Update README.md

README.md

@@ -21,6 +21,7 @@ for multi-label classification. In particular, the model is fine-tuned on the CA
 [here](). More precisely, the `train_sequences.fasta` file is the list of protein sequences that were trained on, and the 
 `train_terms.tsv` file contains the gene ontology protein function labels for each protein sequence. For more details on using 
 ESM-2 models for multi-label sequence classification, [see here](https://huggingface.co/docs/transformers/model_doc/esm). 
+Due to the potentially complicated class weighting necessary for the hierarchical ontology, further fine-tuning will be necessary. 
 
 ## Fine-Tuning