EvolutionaryScale
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esmc-600m-2024-12

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 ESM Cambrian is a parallel model family to our flagship ESM3 generative models. While ESM3 focuses on controllable generation of proteins for therapeutic and many other applications, ESM C focuses on creating representations of the underlying biology of proteins. ESM C scales up data and training compute to deliver dramatic performance improvements over ESM2.
-![image/png](https://cdn-uploads.huggingface.co/production/uploads/66ec90313b250e9eca17af5a/7wMGYSibjEuUJjq62gXAg.png)
 ## Usage

 ESM Cambrian is a parallel model family to our flagship ESM3 generative models. While ESM3 focuses on controllable generation of proteins for therapeutic and many other applications, ESM C focuses on creating representations of the underlying biology of proteins. ESM C scales up data and training compute to deliver dramatic performance improvements over ESM2.
+![image/png](https://cdn-uploads.huggingface.co/production/uploads/6306e13e5b87d4feaad68405/F6SS--Yt9bLctcEE-Ydcl.png)
+ESM has consistently set the state of the art for protein language models. Now ESM C unlocks a new frontier of performance with scaling up to 6 billion parameters. The ESM C family delivers significant inference time performance gains, matching and even exceeding the capabilities of far larger previous generation models. Contact precision (P@L) is computed on CASP15.
 ## Usage