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+ fig_num,image_path,image_caption,golden_corpus,positive_corpus
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+ Pelvic Pain Figureure 1,human_repro/images/Pelvic Pain Figureure 1.jpg,"Figure 1. Endometriosis. (Image Source Bruce Blaus via Wikimedia Commons, CC BY 3.0)","Endometriosis is when tissue that normally lines the endometrium grows outside of the uterus, causing pelvic pain (See Figure 1). This can occur at any time throughout female reproductive years.","{'effa30ce-b78b-40c2-a49f-62027347b00c': 'Endometriosis is when tissue that normally lines the endometrium grows outside of the uterus, causing pelvic pain (See Figure 1). This can occur at any time throughout female reproductive years.', '754e94cf-0bf9-4f8f-a604-1038144a7b80': 'Endometriosis can cause cyclic pain, dysmenorrhea, and severe dyspareunia, or painful intercourse. If a female has endometriosis, she has a 30-40% chance of being infertile. Endometriosis can cause a female to become infertile by trapping the ovum, or the cytokine and prostaglandin production that may interrupt the ovulation, tubal function, and luteal phase detection. Management of endometriosis typically involves treatment through hormonal therapies or excision surgery.'}"
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+ Pelvic Pain Figureure 2,human_repro/images/Pelvic Pain Figureure 2.jpg,"Figure 2. Ectopic Pregnancy. (Image Source: Bruce Blaus via Wikimedia Commons, CC BY SA 4.0)","An ectopic pregnancy occurs when the implantation of a zygote takes place outside of the uterus or in an abnormal location within the uterus (See Figure 2). In 95% of ectopic pregnancies occur in the fallopian tubes, but they can also occur in the abdomen or cervix. The pain may be characterized as unilateral or generalized, crampy or sharp. Vaginal bleeding and spotting can also occur. Certain individuals may also encounter nonspecific symptoms, such as an unusual urge to defecate, which can occasionally overlap with common pregnancy signs.","{'096efd0c-fec8-446a-92e5-86f9aa6cbb93': 'An ectopic pregnancy occurs when the implantation of a zygote takes place outside of the uterus or in an abnormal location within the uterus (See Figure 2). In 95% of ectopic pregnancies occur in the fallopian tubes, but they can also occur in the abdomen or cervix. The pain may be characterized as unilateral or generalized, crampy or sharp. Vaginal bleeding and spotting can also occur. Certain individuals may also encounter nonspecific symptoms, such as an unusual urge to defecate, which can occasionally overlap with common pregnancy signs.', 'c281d2eb-14c5-4c78-a63a-0056e316abef': 'The risk of an ectopic pregnancy is elevated in cases of a previous ectopic pregnancy, a history of pelvic infection (e.g., chlamydia and gonorrhea), the use of an intrauterine device (IUD), the presence of endometriosis, or factors that impede ovum transport, including the use of oral contraceptive pills (OCP) or smoking.'}"
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+ Sex Chromosome Number Disorders Figureure 1,human_repro/images/Sex Chromosome Number Disorders Figureure 1.jpg,"Figure 1. The symptoms of Klinefelter’s syndrome in a human male. (Image Source: Wikimedia, CC BY SA)","Klinefelter syndrome affects 1 in 1,000 newborn boys and is most often undiagnosed preceding puberty. Those with Klinefelter syndrome tend to be taller than average with incomplete musculature, enlarged breasts, small testis, decreased testosterone production, male infertility, and decreased motor skills and dexterity (Figure 1). However, those with Klinefelter Syndrome can usually be sexually active without much issue.","{'74466012-6dea-4879-9154-ae1a6dafd81b': 'Klinefelter syndrome is caused by the presence of an additional X sex chromosome. For instance, 47XXY. It is caused by maternal meiotic nondisjunction, the incidence of which increases with maternal age. There is no increased risk of reoccurrence: if it happens once, it is not likely to happen again. Rather, it is the same risk of occurrence as in the general population.', '0809c605-f076-4f11-ba70-9c1a9cb0fe3a': 'Klinefelter syndrome affects 1 in 1,000 newborn boys and is most often undiagnosed preceding puberty. Those with Klinefelter syndrome tend to be taller than average with incomplete musculature, enlarged breasts, small testis, decreased testosterone production, male infertility, and decreased motor skills and dexterity (Figure 1). However, those with Klinefelter Syndrome can usually be sexually active without much issue.'}"
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+ Menopause Figureure 1,human_repro/images/Menopause Figureure 1.jpg,Figure 1. Hormones during the menstrual cycle and at menopause,"During the transition from menses to menopause, there are some hormonal changes due to the decrease in ovarian cells’ sensitivity to gonadotropin stimulation, exhaustion of the supply of ovarian follicles, and loss of ovarian cells that secrete estrogen and progesterone. As a result, estrogen and inhibin levels are reduced. Decreased estrogen and inhibin remove the negative feedback on the higher centers. As the negative feedback is removed, gonadotropin, FSH, and LHs level are increased (Figure 1). A state of hypergonadotropic-amenorrhea develops among menopausal women.","{'d9d4434b-bbc9-4f76-9a13-eed4cdae5837': 'During the transition from menses to menopause, there are some hormonal changes due to the decrease in ovarian cells’ sensitivity to gonadotropin stimulation, exhaustion of the supply of ovarian follicles, and loss of ovarian cells that secrete estrogen and progesterone. As a result, estrogen and inhibin levels are reduced. Decreased estrogen and inhibin remove the negative feedback on the higher centers. As the negative feedback is removed, gonadotropin, FSH, and LHs level are increased (Figure 1). A state of hypergonadotropic-amenorrhea develops among menopausal women.'}"
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+ Ejaculate Figureure 1,human_repro/images/Ejaculate Figureure 1.jpg,"Figure 1. The sperm cell consists of a head, mid-piece, and a tail. The acrosome covers the head. (Image Source: OpenStax Anatomy & Physiology 2E, CC BY 4.0. Access for free at OpenStax Anatomy and Physiology 2E online)","Sperm have a distinctive head, mid-piece, and tail region (Figure 1).","{'afab28c5-5def-4ee4-942f-2068456d8bdc': 'Sperm are smaller than most cells in the body; in fact, the volume of a sperm cell is 85,000 times less than that of the female gamete. Approximately 100 to 300 million sperm are produced daily, whereas women typically ovulate only one oocyte per month.', '2ae1fa9d-62f8-4026-b2b8-f1755b2c100a': 'Sperm have a distinctive head, mid-piece, and tail region (Figure 1).', '6ba47cd5-e9db-412d-83e8-550c80fa0951': 'The head of the sperm contains an extremely compact nucleus with a haploid number of chromosomes and very little cytoplasm. These contribute to the overall small size of the sperm (the head is only 5mm long). A structure called the acrosome covers the anterior 2/3 of the nucleus at the head of the sperm cell, the “Acrosomal cap”. This cap is filled with lysosomal and hydrolytic enzymes that participate and initiate acrosomal reactions at the time of fertilization. The acrosomal reaction helps sperm bind and burrow through the Zona Pellucida surrounding the egg and complete the process of fertilization.', '713c4f37-f1e1-4471-8dd1-419008661e06': 'The constriction between the head and the mid-piece called the neck.', '1018b0f2-1c81-4f44-abe8-276b4a53d729': 'The mid-piece of the sperm contains a tightly packed mitochondrion that provides the ATP and energy required for movement. The tail, which extends from the mid-piece, consists of a principal flagella structure around 45µm long that is highly mobile, and an end piece, a 5 µm long fibrous sheath of disorganized flagellum structure. Movement of the entire sperm cell occurs through the tail.'}"
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+ Accessory Glands Figureure 1,human_repro/images/Accessory Glands Figureure 1.jpg,"Figure 1. Bold labels highlight the placement of seminal vesicles, paired ejaculatory ducts into prostatic urethra, bulbourethral glands. (Image Source: vector by Tsaitgaist, CC BY 3.0).","Paired seminal vesicles are located on the posterior surface of the urinary bladder, lateral to the ampulla of the ductus deferens. As sperm pass through the ampulla of the ductus deferens at ejaculation, they mix with fluid from the associated seminal vesicle (Figure 1).","{'ae618ad4-4619-49ab-b159-16e644f1f7aa': 'Paired seminal vesicles are located on the posterior surface of the urinary bladder, lateral to the ampulla of the ductus deferens. As sperm pass through the ampulla of the ductus deferens at ejaculation, they mix with fluid from the associated seminal vesicle (Figure 1).', '46692f8f-a66c-4590-bf52-6737c116f731': 'The paired seminal vesicles are glands that contribute approximately 75% of semen by volume. Seminal vesicles secrete whitish yellow, thick and viscous fluid. The fluid contains large amounts of fructose for the sperms’ nourishment and prostaglandins, which are used by the sperms’ mitochondria to generate ATP to allow movement through the female reproductive tract. The secretion of seminal vesicles is under the influence of testosterone.', 'c8c93ad9-cc62-4329-8eec-d8fda87f328c': 'The seminal fluid contains both sperm and seminal vesicle secretions. This fluid moves into the associated ejaculatory duct, a short structure formed from the ampulla of the ductus deferens and the duct of the seminal vesicle. The paired ejaculatory ducts transport the seminal fluid into prostatic urethra which runs through the prostate gland.'}"
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+ Scrotum and Testes Figureure 1,human_repro/images/Scrotum and Testes Figureure 1.jpg,"Figure 1. The Scrotum and Testes (Image Source: OpenStax Anatomy & Physiology 2E, CC BY 4.0. Access for free at OpenStax Anatomy and Physiology 2E online)","The scrotum is a skin-covered, highly-pigmented muscular sac containing the testes. The scrotum extends from the body behind the penis (Figure 1). This location is important in sperm production, which occurs within the testes and proceeds more efficiently when the testes are kept 2 to 4°C below core body temperature. The scrotum is homologous to the labia majora in the female during fetal development.","{'4ee86237-8f6b-469c-bd30-027be448ead2': 'The scrotum is a skin-covered, highly-pigmented muscular sac containing the testes. The scrotum extends from the body behind the penis (Figure 1). This location is important in sperm production, which occurs within the testes and proceeds more efficiently when the testes are kept 2 to 4°C below core body temperature. The scrotum is homologous to the labia majora in the female during fetal development.', 'babeea9c-cc00-4ed2-aa3d-ceb6c6af7fb6': 'The scrotum is homologous to the labia majora in the female during fetal development.', '242d4496-11a6-4c48-96e6-be7ad788c0ba': 'The dartos muscle is a\xa0subcutaneous\xa0smooth muscle that makes up the wall of the scrotum. It continues internally to make up the scrotal septum that divides the scrotum into two compartments, each housing one testis. Descending from the internal oblique muscle of the abdominal wall are the two cremaster muscles, which cover each testis like a muscular net. By contracting simultaneously, the dartos and cremaster muscles can elevate the testes in cold weather (or water), moving the testes closer to the body and decreasing the surface area of the scrotum to retain heat. Alternatively, as the environmental temperature increases, the scrotum relaxes, moving the testes farther from the body’s core and increasing the scrotal surface area, which promotes heat loss. Externally, the scrotum has a raised medial thickening on the surface called the raphae defines the separation between the two scrotal sacs.'}"
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+ Scrotum and Testes Figureure 2,human_repro/images/Scrotum and Testes Figureure 2.jpg,"Figure 2. (Image Source: OpenStax Anatomy & Physiology 2E, CC BY 4.0. Access for free at OpenStax Anatomy and Physiology 2E online)","During their migration to the scrotum, the testes are enclosed in part by the peritoneum membrane. As they descend into the scrotum, the anterior and lateral surfaces of each testis remain covered by the peritoneal membrane, the tunica vaginalis layer, a serous membrane that has both a parietal and a thin visceral layer of the peritoneum (Figure 2).","{'bf908a3f-4ff8-47ec-a1c6-92e814414ccd': 'The\xa0testes\xa0(singular = testis) are the male\xa0gonads, the primary sex organ in the male reproductive system. They produce both sperms, in addition to the production and secretion of androgens and the male sex hormone, testosterone. Testes are active throughout the reproductive lifespan of the male.', '59de643b-bdb7-4580-a98a-daf329a4496e': 'The testes are paired oval structures, each approximately 4 to 5 cm in length and housed within the scrotum. During fetal development, the testes develop as abdominal organs. In the seventh month of the developmental period, each testis moves to descend into the scrotal cavity.\xa0 At birth, testes reach their final destination in the scrotal sacs. This process is called the “descent of the testis.”', '48c611a0-f890-49d9-a058-2c6806ac3d20': 'During their migration to the scrotum, the testes are enclosed in part by the peritoneum membrane. As they descend into the scrotum, the anterior and lateral surfaces of each testis remain covered by the peritoneal membrane, the tunica vaginalis layer, a serous membrane that has both a parietal and a thin visceral layer of the peritoneum (Figure 2).'}"
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+ Scrotum and Testes Figureure 4,human_repro/images/Scrotum and Testes Figureure 4.jpg,Figure 4. Testicular veins,"The testes get nourishment and oxygenated blood through the testicular artery, a direct branch of the abdominal aorta, as they develop as abdominal organs. In the spermatic cord, the testicular artery is surrounded by a group of veins, Pampiniform plexus, that drain waste and return deoxygenated blood back to the testicular vein in the abdomen (Figure 4). This pampiniform plexus reduces the temperature around the testes and works as a countercurrent heat-exchange system to cool down the arterial blood before it enters the testis.","{'7f94154c-a73f-49d0-872a-d5c989ded6ae': 'The testes get nourishment and oxygenated blood through the testicular artery, a direct branch of the abdominal aorta, as they develop as abdominal organs. In the spermatic cord, the testicular artery is surrounded by a group of veins, Pampiniform plexus, that drain waste and return deoxygenated blood back to the testicular vein in the abdomen (Figure 4). This pampiniform plexus reduces the temperature around the testes and works as a countercurrent heat-exchange system to cool down the arterial blood before it enters the testis.'}"
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+ Scrotum and Testes Figureure 5,human_repro/images/Scrotum and Testes Figureure 5.jpg,Figure 5. Varicocele (Image Source: (c) Mayo Foundation. Used here for educational purposes under fair use),"Varococoele are enlarged dilated pampiniform plexus veins that surround the testes. The veins feel like cords or worms within the scrotal sac and may be visible on the surface of scrotum. This may be caused by an upper venous drainage obstruction in the pelvis or abdomen, which leads to the stagnation of blood around the testes, impeding their heat-regulatory system and leaving the testes in a hot environment.  Varicoceles cause low sperm production and decreased sperm quality, and are a common cause of male infertility (Figure 5).","{'a582c35b-6a25-4017-8f31-9ce73499e06d': 'Varococoele are enlarged dilated pampiniform plexus veins that surround the testes. The veins feel like cords or worms within the scrotal sac and may be visible on the surface of scrotum. This may be caused by an upper venous drainage obstruction in the pelvis or abdomen, which leads to the stagnation of blood around the testes, impeding their heat-regulatory system and leaving the testes in a hot environment.\xa0 Varicoceles cause low sperm production and decreased sperm quality, and are a common cause of male infertility (Figure 5).'}"
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+ Hormones of the Menstrual Cycle Figureure 1,human_repro/images/Hormones of the Menstrual Cycle Figureure 1.jpg,"Figure 1. Hormone Levels in Ovarian and Menstrual Cycles. The correlation of the hormone levels and their effects on the female reproductive system is shown in this timeline of the ovarian and menstrual cycles. (Image Source: OpenStax Anatomy & Physiology 2E, CC BY 4.0. Access for free at OpenStax Anatomy and Physiology 2E online)","The cycle consists of two parts, the ovarian and uterine cycles. The ovarian cycle governs the preparation of endocrine gonads and the release of eggs, while the uterine cycle governs the preparation and maintenance of the uterine lining. These two cycles occur concurrently and are coordinated over a 22–32-day cycle, with an average length of 28 days (Figure 1).","{'6abb7fbf-ae8f-4611-8f10-b90802348b77': 'The cycle consists of two parts, the ovarian and uterine cycles. The\xa0ovarian cycle governs the preparation of endocrine gonads and the release of eggs, while the uterine cycle governs the preparation and maintenance of the uterine lining. These two cycles occur concurrently and are coordinated over a 22–32-day cycle, with an average length of 28 days (Figure 1).'}"
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+ Hormones of the Menstrual Cycle Figureure 2,human_repro/images/Hormones of the Menstrual Cycle Figureure 2.jpg,"Figure 2. Hormonal action during ovarian and Uterine cycles. (Image Source: OpenStax Anatomy & Physiology 2E, CC BY 4.0. Access for free at OpenStax Anatomy and Physiology 2E online)","The uterine cycle consists of the menstrual, proliferative, and secretory phases. Figure 2 visually compares the ovarian and uterine cycles and Figure 1 shows the commensurate hormone levels in each.","{'5531c552-cd65-4b45-a953-29a8515040ec': 'The uterine cycle consists of the menstrual, proliferative, and secretory phases. Figure 2 visually compares the ovarian and uterine cycles and Figure 1 shows the commensurate hormone levels in each.'}"
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+ Female External Genitalia Figureure 5,human_repro/images/Female External Genitalia Figureure 5.jpg,,"Figure 5. Batholin’s cyst. Source: Ernest, Diseases of Women",{}
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+ fig_num,sub_section_headings,images-src,image_caption
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+ Pelvic Pain Figureure 1,Endometriosis,https://iastate.pressbooks.pub/app/uploads/sites/43/2023/10/Blausen_0349_Endometriosis.png,"Figure 1. Endometriosis. (Image Source Bruce Blaus via Wikimedia Commons, CC BY 3.0)"
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+ Pelvic Pain Figureure 2,Ectopic Pregnancy,https://iastate.pressbooks.pub/app/uploads/sites/43/2023/10/640px-Ectopic_Pregnancy.png,"Figure 2. Ectopic Pregnancy. (Image Source: Bruce Blaus via Wikimedia Commons, CC BY SA 4.0)"
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+ Sex Chromosome Number Disorders Figureure 1,Sex Chromosome Number Disorders,https://iastate.pressbooks.pub/app/uploads/sites/43/2023/03/Klinefelters-Wikimedia.png,"Figure 1. The symptoms of Klinefelter’s syndrome in a human male. (Image Source: Wikimedia, CC BY SA)"
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+ Menopause Figureure 1,Hormonal changes at menopause,https://iastate.pressbooks.pub/app/uploads/sites/43/2022/02/Menopause-hormones-1024x480.png,Figure 1. Hormones during the menstrual cycle and at menopause
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+ Ejaculate Figureure 1,Normal Structure of Sperm,https://openstax.org/apps/archive/20220118.185250/resources/63e4c7b77be4e97c88b4c649fbd6c6472cf58466,"Figure 1. The sperm cell consists of a head, mid-piece, and a tail. The acrosome covers the head. (Image Source: OpenStax Anatomy & Physiology 2E, CC BY 4.0. Access for free at OpenStax Anatomy and Physiology 2E online)"
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+ Accessory Glands Figureure 1,Seminal Vesicles,https://iastate.pressbooks.pub/app/uploads/sites/43/2022/02/male-reproductive-system.png,"Figure 1. Bold labels highlight the placement of seminal vesicles, paired ejaculatory ducts into prostatic urethra, bulbourethral glands. (Image Source: vector by Tsaitgaist, CC BY 3.0)."
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+ Scrotum and Testes Figureure 1,Scrotum,https://iastate.pressbooks.pub/app/uploads/sites/43/2022/02/testes.jpg,"Figure 1. The Scrotum and Testes (Image Source: OpenStax Anatomy & Physiology 2E, CC BY 4.0. Access for free at OpenStax Anatomy and Physiology 2E online)"
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+ Scrotum and Testes Figureure 2,Testes,https://bio.libretexts.org/@api/deki/files/49002/clipboard_e7a63781fd41dc35da466c3b6d0b5e1a5.png?revision=1,"Figure 2. (Image Source: OpenStax Anatomy & Physiology 2E, CC BY 4.0. Access for free at OpenStax Anatomy and Physiology 2E online)"
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+ Scrotum and Testes Figureure 4,Blood Vessels Around Testes,https://upload.wikimedia.org/wikipedia/commons/1/1b/Gray590.png,Figure 4. Testicular veins
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+ Scrotum and Testes Figureure 5,Varicocele,https://www.drugs.com/mayo/media/039DE1C2-DE86-4301-8695-63AA2E166DE2.jpg,Figure 5. Varicocele (Image Source: (c) Mayo Foundation. Used here for educational purposes under fair use)
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+ Hormones of the Menstrual Cycle Figureure 1,Menstrual Cycle,https://iastate.pressbooks.pub/app/uploads/sites/43/2021/02/ovarian-uterine-cycles.jpg,"Figure 1. Hormone Levels in Ovarian and Menstrual Cycles. The correlation of the hormone levels and their effects on the female reproductive system is shown in this timeline of the ovarian and menstrual cycles. (Image Source: OpenStax Anatomy & Physiology 2E, CC BY 4.0. Access for free at OpenStax Anatomy and Physiology 2E online)"
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+ Hormones of the Menstrual Cycle Figureure 2,The Uterine Cycle,https://iastate.pressbooks.pub/app/uploads/sites/43/2021/02/follicular-ovarian-uterine.jpg,"Figure 2. Hormonal action during ovarian and Uterine cycles. (Image Source: OpenStax Anatomy & Physiology 2E, CC BY 4.0. Access for free at OpenStax Anatomy and Physiology 2E online)"
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+ Female External Genitalia Figureure 5,Bartholin’s cyst/abscess (Figure 5),https://iastate.pressbooks.pub/app/uploads/sites/43/2020/10/Abscessvagina-1024x803.png,"Figure 5. Batholin’s cyst. Source: Ernest, Diseases of Women"
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+ Scrotum and Testes Figureure 1,3c3b3827-4ebf-43f4-baa4-d6bc6064fb25,1
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+ Scrotum and Testes Figureure 1,4ee86237-8f6b-469c-bd30-027be448ead2,2
25
+ Scrotum and Testes Figureure 1,babeea9c-cc00-4ed2-aa3d-ceb6c6af7fb6,1
26
+ Scrotum and Testes Figureure 1,242d4496-11a6-4c48-96e6-be7ad788c0ba,1
27
+ Scrotum and Testes Figureure 2,6a379d18-0398-45b7-b0bc-53520fa468b7,1
28
+ Scrotum and Testes Figureure 2,7ed3b7c1-8af3-4872-98bf-83f8368fd808,1
29
+ Scrotum and Testes Figureure 2,bf908a3f-4ff8-47ec-a1c6-92e814414ccd,1
30
+ Scrotum and Testes Figureure 2,59de643b-bdb7-4580-a98a-daf329a4496e,1
31
+ Scrotum and Testes Figureure 2,48c611a0-f890-49d9-a058-2c6806ac3d20,2
32
+ Scrotum and Testes Figureure 4,011c3e1f-94bf-4f77-8063-7708df45f2f3,1
33
+ Scrotum and Testes Figureure 4,7f94154c-a73f-49d0-872a-d5c989ded6ae,2
34
+ Scrotum and Testes Figureure 5,5bf15f9a-b38e-47e2-8b51-d90448577c37,1
35
+ Scrotum and Testes Figureure 5,a582c35b-6a25-4017-8f31-9ce73499e06d,2
36
+ Hormones of the Menstrual Cycle Figureure 1,87ec6ddd-a3cd-453c-996e-ffb6b485a587,1
37
+ Hormones of the Menstrual Cycle Figureure 1,6abb7fbf-ae8f-4611-8f10-b90802348b77,2
38
+ Hormones of the Menstrual Cycle Figureure 2,191c34e4-7ef9-4b65-9500-18d080311c5f,1
39
+ Hormones of the Menstrual Cycle Figureure 2,16455b30-e6f7-4e07-b4a4-5fbff6cfa1c4,1
40
+ Hormones of the Menstrual Cycle Figureure 2,5531c552-cd65-4b45-a953-29a8515040ec,2
41
+ Female External Genitalia Figureure 5,3a5a92db-c247-4f1b-bcc6-193933bce2f4,2