Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: host cell endoplasmic reticulum lumen ; host cell endoplasmic reticulum membrane ; membrane ; ATP binding ; cysteine-type endopeptidase activity ; RNA binding ; RNA helicase activity ; RNA-dependent RNA polymerase activity ; DNA-templated transcription ; proteolysis ; RNA-protein covalent cross-linking ; viral RNA genome replication


GO Terms Prediction

Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: membrane ; metal ion binding ; potassium channel activity ; voltage-gated monoatomic ion channel activity ; regulation of monoatomic ion transmembrane transport


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: cytoplasm ; nucleus ; ATP binding ; MAP kinase activity ; protein serine kinase activity ; protein serine/threonine kinase activity ; innate immune response ; intracellular signal transduction ; pattern recognition receptor signaling pathway ; protein phosphorylation


Instruction: Predict the GO term based on the protein sequence.

Output: extracellular space ; hormone activity ; identical protein binding ; hormone biosynthetic process ; thyroid hormone generation


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: cell surface ; cellular bud ; extracellular region ; fungal-type cell wall ; hyphal cell wall ; plasma membrane ; heme binding ; metal ion binding ; intracellular iron ion homeostasis ; single-species biofilm formation on inanimate substrate


Instruction: Predict the GO term based on the protein sequence.

Output: membrane ; NAD binding ; NADH dehydrogenase activity ; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor ; UDP-N-acetylglucosamine 6-dehydrogenase activity ; cell wall organization ; O antigen biosynthetic process ; polysaccharide biosynthetic process


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: plasma membrane ; ABC-type transporter activity ; ATP binding ; ATP hydrolysis activity ; oxidoreductase activity


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: endocytic vesicle ; spherical high-density lipoprotein particle ; very-low-density lipoprotein particle ; amyloid-beta binding ; apolipoprotein A-I receptor binding ; chemorepellent activity ; cholesterol binding ; cholesterol transfer activity ; enzyme binding ; heat shock protein binding ; high-density lipoprotein particle binding ; high-density lipoprotein particle receptor binding ; phosphatidylcholine-sterol O-acyltransferase activator activity ; phospholipid binding ; protein homodimerization activity ; adrenal gland development ; blood vessel endothelial cell migration ; cholesterol biosynthetic process ; cholesterol efflux ; cholesterol homeostasis ; cholesterol import ; endothelial cell proliferation ; G protein-coupled receptor signaling pathway ; glucocorticoid metabolic process ; high-density lipoprotein particle assembly ; high-density lipoprotein particle remodeling ; integrin-mediated signaling pathway ; lipid storage ; lipoprotein biosynthetic process ; negative regulation of cell adhesion molecule production ; negative regulation of cytokine production involved in immune response ; negative regulation of heterotypic cell-cell adhesion ; negative regulation of hydrolase activity ; negative regulation of inflammatory response ; negative regulation of interleukin-1 beta production ; negative regulation of tumor necrosis factor-mediated signaling pathway ; negative regulation of very-low-density lipoprotein particle remodeling ; peptidyl-methionine modification ; phosphatidylcholine biosynthetic process ; phospholipid efflux ; phospholipid homeostasis ; positive regulation of cholesterol efflux ; positive regulation of cholesterol metabolic process ; positive regulation of CoA-transferase activity ; positive regulation of hydrolase activity ; positive regulation of phagocytosis ; positive regulation of phospholipid efflux ; positive regulation of Rho protein signal transduction ; positive regulation of stress fiber assembly ; positive regulation of substrate adhesion-dependent cell spreading ; protein oxidation ; protein stabilization ; regulation of Cdc42 protein signal transduction ; regulation of intestinal cholesterol absorption ; regulation of protein phosphorylation ; reverse cholesterol transport ; triglyceride homeostasis ; vitamin transport


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: endomembrane system ; endoplasmic reticulum ; endoplasmic reticulum membrane ; nuclear membrane ; dolichyl-phosphate-mannose-protein mannosyltransferase activity ; cell wall mannoprotein biosynthetic process ; chain elongation of O-linked mannose residue ; protein O-linked mannosylation


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: cytoplasm ; microtubule organizing center ; mitochondrion ; nuclear speck ; nucleus ; spindle ; DNA-binding transcription factor activity ; nuclear glucocorticoid receptor activity ; nuclear receptor activity ; sequence-specific DNA binding ; steroid binding ; steroid hormone binding ; zinc ion binding ; cellular response to glucocorticoid stimulus ; cellular response to steroid hormone stimulus ; chromatin organization ; positive regulation of transcription by RNA polymerase II


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: extracellular region ; host cell cytoplasm ; host cell nucleus ; T=4 icosahedral viral capsid ; DNA binding ; RNA binding ; structural molecule activity ; microtubule-dependent intracellular transport of viral material towards nucleus ; mitigation of host antiviral defense response ; viral entry into host cell ; viral penetration into host nucleus


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Input: NLWQFEMLIMKIAKTSGFMFYSSYGCYCGWGGHGRPQDASDRCCFVHDCCYGKVTGVVVCGGDDPCKXQICECDRVAATCFRDNKYWFFPAK

Output: extracellular region ; calcium ion binding ; phospholipase A2 activity ; toxin activity ; arachidonic acid secretion ; lipid catabolic process ; phospholipid metabolic process


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: host cell endoplasmic reticulum membrane ; host cell lipid droplet ; host cell mitochondrial membrane ; host cell nucleus ; membrane ; ribonucleoprotein complex ; viral envelope ; viral nucleocapsid ; virion membrane ; RNA binding ; structural molecule activity ; clathrin-dependent endocytosis of virus by host cell ; fusion of virus membrane with host endosome membrane ; mitigation of host antiviral defense response ; virion attachment to host cell


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Input: MASGVMVSDDVVKVFNDMKVRHQLSPEEAKKRKKAVIFCLSDDKKTIILEPGKEILQGDVGCNVEDPYKTFVKMLPRNDCRYALYDALYETKETKKEDLVFVFWAPEEASLKSKMIYASSKDAIRKRFTGIKHEWQTNTYDDINDPCNLADKLGGNTVVSLEGKSLRS

Output: actin cytoskeleton ; cell cortex ; cytoplasm ; membrane ; midbody ; nuclear matrix ; actin filament binding ; actin filament depolymerization ; cytoskeleton organization ; cytoskeleton-dependent cytokinesis ; regulation of cell morphogenesis


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: Cdc42 GTPase complex ; cell cortex ; cell tip ; cytosol ; lateral cortical node ; nucleus ; histone arginine N-methyltransferase activity ; cellular response to osmotic stress ; establishment or maintenance of bipolar cell polarity regulating cell shape ; histone arginine methylation ; lateral cortical node assembly ; peptidyl-arginine N-methylation ; protein localization to lateral cortical node ; regulation of DNA-templated transcription ; regulation of establishment or maintenance of bipolar cell polarity regulating cell shape


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Input: MVKAVAVLRGDSKITGTVTFEQANESAPTTVSWNITGHDPNAERGMHIHQFGDNTNGCTSAGPHYNPFKKTHGAPTDEVRHVGDLGNIKTDAEGNAVGSVQDKLIKVIGAESILGRTIVVHAGTDDLGRGGNEESKKTGNAGPRPACGVIGIA

Output: cytoplasm ; copper ion binding ; superoxide dismutase activity


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: plasma membrane ; ATP binding ; protein serine kinase activity ; protein serine/threonine kinase activity ; protein phosphorylation


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: host cell cytoplasm ; host cell endoplasmic reticulum ; host cell membrane ; host cell nucleus ; host cell perinuclear region of cytoplasm ; membrane ; ATP binding ; ATP hydrolysis activity ; cysteine-type deubiquitinase activity ; cysteine-type endopeptidase activity ; endonuclease activity ; lyase activity ; RNA binding ; RNA endonuclease activity ; RNA helicase activity ; RNA-dependent RNA polymerase activity ; serine-type endopeptidase activity ; zinc ion binding ; DNA-templated transcription ; induction by virus of host autophagy ; modulation by symbiont of host protein ubiquitination ; proteolysis ; suppression by virus of host ISG15-protein conjugation ; suppression by virus of host JAK-STAT cascade ; suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity ; suppression by virus of host mRNA export from nucleus ; suppression by virus of host NF-kappaB cascade ; suppression by virus of host type I interferon-mediated signaling pathway ; suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity ; viral protein processing ; viral RNA genome replication


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: mitochondrial inner membrane ; mitochondrion ; nucleus ; DNA endonuclease activity ; metal ion binding ; nucleic acid binding ; RNA endonuclease activity ; single-stranded DNA endodeoxyribonuclease activity ; mitochondrial DNA catabolic process ; mitochondrial RNA catabolic process


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: identical protein binding ; tyrosine ammonia-lyase activity ; phenylpropanoid biosynthetic process ; protein homotetramerization ; tyrosine catabolic process


Instruction: Predict the GO term based on the protein sequence.

Output: external side of plasma membrane ; membrane ; alkaline phosphatase activity ; ATP binding ; ATP hydrolysis activity ; metal ion binding ; P-type calcium transporter activity ; calcium ion transmembrane transport ; calcium ion transport ; cellular response to magnesium ion


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: cytosol ; nucleoplasm ; nucleus ; chromatin binding ; DNA-binding transcription repressor activity, RNA polymerase II-specific ; E-box binding ; metal ion binding ; cartilage development ; cell differentiation ; cellular response to amino acid stimulus ; central nervous system development ; cochlea morphogenesis ; embryonic camera-type eye morphogenesis ; embryonic skeletal system morphogenesis ; keratinocyte proliferation ; negative regulation of DNA-templated transcription ; negative regulation of endothelial cell differentiation ; negative regulation of keratinocyte proliferation ; pattern specification process ; positive regulation of neuron differentiation ; positive regulation of transcription by RNA polymerase II ; regulation of mesenchymal cell proliferation ; regulation of smooth muscle cell differentiation ; regulation of T cell differentiation in thymus ; regulation of transforming growth factor beta receptor signaling pathway ; semicircular canal morphogenesis


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: basolateral plasma membrane ; membrane ; plasma membrane ; protein-containing complex binding ; signaling receptor activity ; thyroid-stimulating hormone receptor activity ; adenylate cyclase-activating G protein-coupled receptor signaling pathway ; cell surface receptor signaling pathway ; cellular response to glycoprotein ; cellular response to thyrotropin-releasing hormone ; gamete generation ; response to human chorionic gonadotropin ; response to thyroid hormone ; skeletal system development ; thyroid-stimulating hormone signaling pathway


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Input: MRTLWIMAVLLVGVEGSLWQFGKMINYVMGESGVLQYLSYGCYCGLGGQGQPTDATDRCCFVHDCCYGKVTGCDPKIDSYTYSKKNGDVVCGGDDPCKKQICECDRVATTCFRDNKDTYDIKYWFYGAKNCQEKSEPC

Output: extracellular region ; calcium ion binding ; phospholipase A2 activity ; toxin activity ; arachidonic acid secretion ; defense response to bacterium ; lipid catabolic process ; phospholipid metabolic process ; regulation of blood pressure


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Input: MTIRFADKADCAAITEIYNHAVLHTAAIWNDRTVDTDNRLAWYEARQLLGYPVLVSEENGVVTGYASFGDWRSFDGFRYTVEHSVYVHPAHQGKGLGRKLLSRLIDEARRCGKHVMVAGIESQNAASIRLHHSLGFTVTAQMPQVGVKFGRWLDLTFMQLQLDEHAAPDAC

Output: acyltransferase activity, transferring groups other than amino-acyl groups


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: cilium ; Golgi apparatus ; plasma membrane ; receptor complex ; ATP binding ; platelet-derived growth factor alpha-receptor activity ; platelet-derived growth factor binding ; chemotaxis ; embryonic cranial skeleton morphogenesis ; embryonic skeletal system morphogenesis ; positive regulation of kinase activity ; protein phosphorylation ; transmembrane receptor protein tyrosine kinase signaling pathway


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: centrosome ; cytoplasm ; endoplasmic reticulum ; mitochondrial matrix ; mitochondrion ; nucleolus ; nucleus ; PML body ; ATP-dependent DNA/DNA annealing activity ; copper ion binding ; DNA binding ; DNA-binding transcription factor activity, RNA polymerase II-specific ; promoter-specific chromatin binding ; RNA polymerase II cis-regulatory region sequence-specific DNA binding ; cell cycle ; cellular senescence ; circadian behavior ; DNA damage response ; entrainment of circadian clock by photoperiod ; negative regulation of cell growth ; negative regulation of DNA-templated transcription ; negative regulation of progesterone secretion ; nucleotide-excision repair ; oligodendrocyte apoptotic process ; positive regulation of apoptotic process ; positive regulation of intrinsic apoptotic signaling pathway ; positive regulation of transcription by RNA polymerase II ; protein tetramerization ; regulation of peptide hormone secretion ; regulation of prostaglandin secretion ; regulation of transcription by RNA polymerase II


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: cytoplasmic vesicle ; microneme membrane ; plasma membrane ; serine-type endopeptidase activity ; proteolysis


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: plasma membrane ; acyltransferase activity ; glycolipid biosynthetic process ; phosphatidylinositol metabolic process ; phospholipid biosynthetic process


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: axon ; cytoplasm ; dendrite ; filopodium ; growth cone ; microtubule ; neuron projection ; nucleus ; plasma membrane ; sarcolemma ; beta-tubulin binding ; growth factor activity ; microtubule binding ; sodium channel regulator activity ; transmembrane transporter binding ; establishment of neuroblast polarity ; head development ; inhibitory synapse assembly ; microtubule polymerization ; negative regulation of collateral sprouting ; negative regulation of microtubule depolymerization ; neuron differentiation ; neuron migration ; protein localization to plasma membrane ; regulation of ERK5 cascade


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: host cell endoplasmic reticulum-Golgi intermediate compartment membrane ; host cell plasma membrane ; membrane ; viral envelope ; virion membrane ; endocytosis involved in viral entry into host cell ; fusion of virus membrane with host endosome membrane ; fusion of virus membrane with host plasma membrane ; membrane fusion ; positive regulation of viral entry into host cell ; receptor-mediated endocytosis of virus by host cell ; receptor-mediated virion attachment to host cell ; viral entry into host cell


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: actin cortical patch ; mating projection tip ; medial cortex ; actin monomer binding ; Arp2/3 complex binding ; actin cortical patch assembly ; actin filament branching ; Arp2/3 complex-mediated actin nucleation ; endocytosis ; establishment or maintenance of cell polarity ; mitotic actomyosin contractile ring assembly ; mitotic cytokinesis


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Input: AAKYCKLPVRYGPCKKKIPSFYYKWKAKQCLPFDYSGCGGNANRFKTIEECRRTCVG

Output: extracellular region ; potassium channel regulator activity ; serine-type endopeptidase inhibitor activity ; toxin activity


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Input: MSWALEMADTFLDTMRVGPRTYADVRDEINKRGREDREAARTAVHDPERPLLRSPGLLPEIAPNASLGVAHRRTGGTVTDSPRNPVTR

Output: endoplasmic reticulum membrane ; host cell cytoplasm ; host cell nucleus ; molecular sequestering activity ; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: actin fusion focus ; Cdc42 GTPase complex ; cell cortex of cell tip ; cell division site ; cortical dynamic polarity patch ; cytoplasm ; cytosol ; division septum ; nucleus ; plasma membrane ; CTP binding ; G protein activity ; GDP binding ; GTP binding ; GTPase activity ; protein serine/threonine kinase activator activity ; UTP binding ; conjugation with cellular fusion ; establishment or maintenance of cell polarity regulating cell shape ; positive regulation of conjugation with cellular fusion ; positive regulation of mating projection assembly ; positive regulation of pheromone response MAPK cascade ; positive regulation of protein import into nucleus ; protein localization to plasma membrane ; regulation of conjugation with cellular fusion ; signal transduction involved in positive regulation of conjugation with cellular fusion


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: cytoplasm ; GTP binding ; mannose-1-phosphate guanylyltransferase (GTP) activity ; cell wall mannoprotein biosynthetic process ; GDP-mannose biosynthetic process ; protein glycosylation


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: host cell membrane ; host cell perinuclear region of cytoplasm ; membrane ; cysteine-type deubiquitinase activity ; cysteine-type endopeptidase activity ; endonuclease activity ; methyltransferase activity ; omega peptidase activity ; RNA-dependent RNA polymerase activity ; single-stranded RNA binding ; zinc ion binding ; induction by virus of catabolism of host mRNA ; induction by virus of host autophagy ; methylation ; modulation by symbiont of host protein ubiquitination ; proteolysis ; suppression by virus of host gene expression ; suppression by virus of host ISG15-protein conjugation ; suppression by virus of host type I interferon-mediated signaling pathway ; suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity ; viral genome replication ; viral protein processing


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Input: MAPVVQQPAPSFKKTAVVDGVFEEVTLEQYKGKWVLLAFIPLAFTFVCPSEIIAYSEAVKKFAEKDAQVLFASTDSEYTWLAWTNVARKDGGIGKVDFPVLADTNHSLSRDYGVLIEEEGVALRGIFLIDPKGVLRQITINDLPVGRSVEESLRLLEAFQFTEKYGEVCPANWHPGDETIKPSPEASKEYFNKVNK

Output: cell surface ; cytosol ; nucleus ; thioredoxin peroxidase activity ; cell redox homeostasis ; cellular response to oxidative stress ; hydrogen peroxide catabolic process ; response to oxidative stress


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: cytoplasm ; glyoxysome ; nucleus ; peroxisome ; plasma membrane ; catalase activity ; heme binding ; metal ion binding ; hydrogen peroxide catabolic process ; response to hydrogen peroxide ; seed germination


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: host cell plasma membrane ; membrane ; viral envelope ; virion membrane ; structural molecule activity ; viral entry into host cell ; virion attachment to host cell


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Input: MAAGSITTLPALPEDGGSSAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGPKTGPGQKAILFLPMSAKS

Output: extracellular space ; nucleus ; chemoattractant activity ; chemokine binding ; cytokine activity ; fibroblast growth factor receptor binding ; growth factor activity ; heparin binding ; identical protein binding ; integrin binding ; nuclear receptor coactivator activity ; receptor-receptor interaction ; branching involved in ureteric bud morphogenesis ; canonical Wnt signaling pathway ; cell migration involved in sprouting angiogenesis ; cerebellar granule cell precursor proliferation ; chondroblast differentiation ; corticotropin hormone secreting cell differentiation ; endothelial cell proliferation ; ERK1 and ERK2 cascade ; fibroblast growth factor receptor signaling pathway ; glial cell differentiation ; growth factor dependent regulation of skeletal muscle satellite cell proliferation ; hyaluronan catabolic process ; inner ear auditory receptor cell differentiation ; inositol phosphate biosynthetic process ; lung development ; lymphatic endothelial cell migration ; mammary gland epithelial cell differentiation ; negative regulation of blood vessel endothelial cell migration ; negative regulation of cell death ; negative regulation of fibroblast migration ; negative regulation of stem cell proliferation ; negative regulation of wound healing ; neuroblast proliferation ; organ induction ; osteoblast differentiation ; phosphatidylinositol biosynthetic process ; positive regulation of angiogenesis ; positive regulation of blood vessel endothelial cell migration ; positive regulation of canonical Wnt signaling pathway ; positive regulation of cardiac muscle cell proliferation ; positive regulation of cell division ; positive regulation of cell fate specification ; positive regulation of cell migration involved in sprouting angiogenesis ; positive regulation of cerebellar granule cell precursor proliferation ; positive regulation of DNA biosynthetic process ; positive regulation of endothelial cell chemotaxis to fibroblast growth factor ; positive regulation of epithelial tube formation ; positive regulation of ERK1 and ERK2 cascade ; positive regulation of gene expression ; positive regulation of inner ear auditory receptor cell differentiation ; positive regulation of lens fiber cell differentiation ; positive regulation of MAP kinase activity ; positive regulation of neuroblast proliferation ; positive regulation of neuroepithelial cell differentiation ; positive regulation of osteoblast differentiation ; positive regulation of phosphatidylinositol 3-kinase activity ; positive regulation of phosphatidylinositol 3-kinase signaling ; positive regulation of phospholipase C activity ; positive regulation of protein kinase B signaling ; positive regulation of protein phosphorylation ; positive regulation of sprouting angiogenesis ; positive regulation of stem cell differentiation ; positive regulation of stem cell proliferation ; positive regulation of transcription by RNA polymerase II ; positive regulation of vascular associated smooth muscle cell proliferation ; positive regulation of vascular endothelial cell proliferation ; protein kinase B signaling ; regulation of cell cycle ; regulation of retinal cell programmed cell death ; release of sequestered calcium ion into cytosol ; response to axon injury ; stem cell development ; stem cell proliferation ; substantia nigra development ; thyroid-stimulating hormone-secreting cell differentiation ; transcription by RNA polymerase II ; wound healing


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: host cell cytoplasm ; host cell nucleus ; host cell plasma membrane ; membrane ; viral nucleocapsid ; RNA binding ; structural molecule activity ; zinc ion binding ; viral budding via host ESCRT complex


Instruction: Predict the GO term based on the protein sequence.

Output: cytosol ; alcohol dehydrogenase (NAD+) activity ; alcohol dehydrogenase activity, zinc-dependent ; butanol dehydrogenase activity ; NAD-retinol dehydrogenase activity ; zinc ion binding ; alcohol metabolic process ; ethanol oxidation ; retinoic acid metabolic process ; retinol metabolic process ; secondary alcohol metabolic process


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: host cell endoplasmic reticulum membrane ; host cell Golgi membrane ; host cell plasma membrane ; membrane ; viral envelope ; virion membrane ; metal ion binding ; fusion of virus membrane with host endosome membrane ; receptor-mediated endocytosis of virus by host cell ; virion attachment to host cell


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: collagen-containing extracellular matrix ; egg coat ; extracellular matrix ; extracellular space ; plasma membrane ; acrosin binding ; carbohydrate binding ; receptor ligand activity ; structural constituent of egg coat ; binding of sperm to zona pellucida ; blastocyst formation ; egg coat formation ; humoral immune response mediated by circulating immunoglobulin ; negative regulation of DNA-templated transcription ; oocyte development ; positive regulation of acrosomal vesicle exocytosis ; positive regulation of acrosome reaction ; positive regulation of antral ovarian follicle growth ; positive regulation of DNA-templated transcription ; positive regulation of humoral immune response ; positive regulation of inflammatory response ; positive regulation of interleukin-4 production ; positive regulation of leukocyte migration ; positive regulation of ovarian follicle development ; positive regulation of T cell proliferation ; positive regulation of type II interferon production ; positive regulation of type IV hypersensitivity


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: nucleolus ; nucleoplasm ; nucleus ; DNA binding ; DNA-binding transcription factor activity, RNA polymerase II-specific ; E-box binding ; protein dimerization activity ; protein-containing complex binding ; chromatin remodeling ; chromosome organization ; DNA damage response ; G1/S transition of mitotic cell cycle ; intracellular iron ion homeostasis ; MAPK cascade ; negative regulation of apoptotic process ; negative regulation of cell division ; negative regulation of monocyte differentiation ; negative regulation of stress-activated MAPK cascade ; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process ; positive regulation of DNA-templated transcription ; positive regulation of epithelial cell proliferation ; positive regulation of fibroblast proliferation ; positive regulation of transcription by RNA polymerase II ; regulation of DNA-templated transcription ; regulation of somatic stem cell population maintenance ; regulation of telomere maintenance ; response to gamma radiation ; response to xenobiotic stimulus


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Input: MENRWQVMIVWQVDRMRIRTWKSLVKHHMYVSGKARGWFYRHHYESPHPRISSEVHIPLGDARLVITTYWGLHTGERDWHLGQGVSIEWRKKRYSTQVDPELADQLIHLYYFDCFSDSAIRKALLGHIVSPRCEYQAGHNKVGSLQYLALAALITPKKIKPPLPSVTKLTEDRWNKPQKTKGHRGSHTMNGH

Output: host cell cytoplasm ; host cell plasma membrane ; membrane ; virion component ; identical protein binding ; lipid binding ; RNA binding ; viral genome replication


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: cytoplasm ; cytosol ; fungal-type vacuole membrane ; mitochondrion ; acetyl-CoA carboxylase activity ; ATP binding ; biotin carboxylase activity ; metal ion binding ; fatty acid biosynthetic process ; malonyl-CoA biosynthetic process ; mitotic nuclear membrane biogenesis


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: plasma membrane ; hydro-lyase activity ; carotenoid metabolic process ; chlorophyll biosynthetic process ; photosynthesis ; spheroidene biosynthetic process


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Input: MPKSPPRFLNSPLSDFFIKWMSRINTWMYRRNDGEGLGGTFQKIPVALLTTTGRKTGQPRVNPLYFLRDGGRVIVAASKGGAEKNPMWYLNLKANPKVQVQIKKEVLDLTARDATDEERAEYWPQLVTMYPSYQDYQSWTDRTIPIVVCEP

Output: peptidoglycan-based cell wall ; plasma membrane ; coenzyme F420 binding ; oxidoreductase activity


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: cytosol ; melanosome ; melanosome membrane ; plasma membrane ; dopachrome isomerase activity ; metal ion binding ; oxidoreductase activity ; cell development ; developmental pigmentation ; melanin biosynthetic process from tyrosine ; positive regulation of neuroblast proliferation ; response to blue light ; ventricular zone neuroblast division


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Input: MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFDDENFILKHTGPGILSMANAGPNTNGSQFFICTVKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQL

Output: cytoplasm ; cytosol ; extracellular region ; nucleus ; cyclosporin A binding ; heparan sulfate binding ; integrin binding ; peptidyl-prolyl cis-trans isomerase activity ; activation of protein kinase B activity ; apoptotic process ; cell adhesion molecule production ; cellular response to oxidative stress ; endothelial cell activation ; leukocyte chemotaxis ; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway ; negative regulation of protein K48-linked ubiquitination ; negative regulation of protein kinase activity ; negative regulation of protein phosphorylation ; negative regulation of stress-activated MAPK cascade ; neutrophil chemotaxis ; platelet activation ; platelet aggregation ; positive regulation of MAPK cascade ; positive regulation of NF-kappaB transcription factor activity ; positive regulation of protein dephosphorylation ; positive regulation of protein phosphorylation ; protein folding ; protein peptidyl-prolyl isomerization ; regulation of apoptotic signaling pathway ; regulation of viral genome replication


Instruction: Predict the GO term based on the protein sequence.

Input: MRTLWIMAVCLIGVEGNFFQFAEMIVKMTGKEAVHSYAIYGCYCGWGGQGKPQDATDRCCFVHDCCYGTVNDCNPKMATYSYSFENGDIVCGDNNLCLKTVCECDRAAAICLGQNVNTYDKNYENYAISHCTEESEQC

Output: extracellular region ; calcium ion binding ; phospholipase A2 activity ; phospholipase A2 inhibitor activity ; toxin activity ; arachidonic acid secretion ; lipid catabolic process ; phospholipid metabolic process


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: lariciresinol reductase activity ; pinoresinol reductase activity ; (+)-lariciresinol biosynthetic process ; (+)-pinoresinol catabolic process ; (+)-secoisolariciresinol biosynthetic process ; (-)-lariciresinol biosynthetic process ; (-)-lariciresinol catabolic process ; (-)-pinoresinol catabolic process ; lignan biosynthetic process


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: endoplasmic reticulum membrane ; heme binding ; iron ion binding ; monooxygenase activity ; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; secologanin synthase activity ; alkaloid metabolic process ; response to jasmonic acid


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: bicellular tight junction ; plasma membrane ; identical protein binding ; structural molecule activity ; bicellular tight junction assembly ; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules ; cell adhesion


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: plasma membrane ; G protein-coupled receptor activity ; olfactory receptor activity ; detection of chemical stimulus involved in sensory perception of smell ; signal transduction


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: plasma membrane ; calcium ion binding ; cell adhesion ; homophilic cell adhesion via plasma membrane adhesion molecules ; nervous system development


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: plasma membrane ; calcium ion binding ; cell adhesion ; homophilic cell adhesion via plasma membrane adhesion molecules ; nervous system development


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: cytosol ; myosin filament ; actin binding ; structural constituent of muscle ; cell adhesion


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: cytosol ; nucleoplasm ; methylated histone binding ; gamete generation ; regulation of DNA-templated transcription


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: nucleus ; DNA-binding transcription factor activity, RNA polymerase II-specific ; metal ion binding ; RNA polymerase II cis-regulatory region sequence-specific DNA binding ; regulation of transcription by RNA polymerase II


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Input: MLSPEAERVLRYLVEVEELAEEVLADKRQIVDLDTKRNQNREGLRALQKDLSLSEDVMVCFGNMFIKMPHPETKEMIEKDQDHLDKEIEKLRKQLKVKVNRLFEAQGKPELKGFNLNPLNQDELKALKVILKG

Output: cytoplasm ; prefoldin complex ; protein folding chaperone complex ; RPAP3/R2TP/prefoldin-like complex ; unfolded protein binding ; protein folding ; protein stabilization


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: plasma membrane ; membrane assembly ; phospholipid homeostasis ; plasma membrane organization ; regulation of membrane lipid distribution


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: nucleus ; DNA-binding transcription factor activity, RNA polymerase II-specific ; metal ion binding ; RNA polymerase II cis-regulatory region sequence-specific DNA binding ; negative regulation of DNA-templated transcription ; regulation of DNA-templated transcription


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: cytosol ; nucleus ; TTT complex ; positive regulation of DNA damage checkpoint ; protein stabilization


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: axonemal microtubule ; ciliary tip ; cilium ; intraciliary transport particle B ; intraciliary transport particle B binding ; cilium assembly ; intraciliary anterograde transport ; intraciliary transport


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: cytosol ; glutamatergic synapse ; presynapse ; SCF ubiquitin ligase complex ; Schaffer collateral - CA1 synapse ; behavioral fear response ; regulation of protein catabolic process at presynapse, modulating synaptic transmission ; regulation of synaptic vesicle exocytosis ; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: cytoplasm ; nucleus ; DNA binding ; DNA-binding transcription factor activity, RNA polymerase II-specific ; protein heterodimerization activity ; flower development ; negative regulation of long-day photoperiodism, flowering ; regulation of transcription by RNA polymerase II


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: cell division site ; plasma membrane ; lipid-linked peptidoglycan transporter activity ; peptidoglycan glycosyltransferase activity ; cell cycle ; cell division ; cell wall organization ; peptidoglycan biosynthetic process ; regulation of cell shape


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: nucleus ; DNA-binding transcription factor activity ; transcription cis-regulatory region binding ; positive regulation of DNA-templated transcription ; regulation of DNA-templated transcription ; regulation of secondary cell wall biogenesis


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Input: MSAAVLLSVLFALACGQAASFCIPTEYTMYVDRRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPHHVTPYFSFPVAVSCKCGKCNTDNSDCIHEAVRTNYCTKPQSFYLGGFSV

Output: cytoplasm ; extracellular space ; hormone activity ; G protein-coupled receptor signaling pathway


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: EMC complex ; protein-folding chaperone binding ; phospholipid metabolic process ; phospholipid transport ; protein folding in endoplasmic reticulum ; protein insertion into ER membrane by stop-transfer membrane-anchor sequence


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: plasma membrane ; tripartite ATP-independent periplasmic transporter complex ; carbohydrate transmembrane transporter activity ; transmembrane transporter activity ; carbohydrate transmembrane transport ; cellular response to salt ; regulation of single-species biofilm formation


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: cell body ; cytoplasm ; dendrite ; heterotrimeric G-protein complex ; neuron projection ; GTPase binding ; signaling receptor complex adaptor activity ; spectrin binding ; cell volume homeostasis ; G protein-coupled receptor signaling pathway ; regulation of cholesterol metabolic process ; regulation of fat cell differentiation ; regulation of gene expression ; regulation of glucose metabolic process ; regulation of hormone metabolic process ; regulation of phospholipid metabolic process ; regulation of triglyceride metabolic process


Instruction: Predict the GO term based on the protein sequence.

Input: MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG

Output: endoplasmic reticulum membrane ; oligosaccharyltransferase complex ; enzyme activator activity ; apoptotic process ; blastocyst development ; negative regulation of apoptotic process ; protein glycosylation ; protein N-linked glycosylation ; regulation of protein stability ; response to nutrient ; response to xenobiotic stimulus


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: cytoplasm ; glycerophosphocholine phosphodiesterase activity ; glycerophosphoinositol glycerophosphodiesterase activity ; glycerophospholipid catabolic process


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: endoplasmic reticulum ; plasma membrane ; amino acid transmembrane transporter activity ; amino acid transmembrane transport ; response to amino acid


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: cytosol ; mitochondrion ; nucleoplasm ; proteasome core complex ; proteasome core complex, beta-subunit complex ; endopeptidase activity ; threonine-type endopeptidase activity ; proteolysis involved in protein catabolic process


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: cytosol ; early endosome membrane ; endosome ; Golgi membrane ; trans-Golgi network ; cognition ; embryonic pattern specification ; Golgi to endosome transport ; protein transport


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: cytoplasm ; microtubule ; GTP binding ; hydrolase activity ; metal ion binding ; structural constituent of cytoskeleton ; microtubule cytoskeleton organization ; mitotic cell cycle


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: nucleus ; STAT family protein binding ; negative regulation of transcription by RNA polymerase II ; positive regulation of protein binding ; protein dephosphorylation


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: chromatin silencing complex ; chromosome ; nucleoplasm ; chromatin binding ; transcription cis-regulatory region binding ; heterochromatin formation ; negative regulation of DNA-templated transcription


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: cytoplasm ; mitochondrion ; cysteine-S-conjugate beta-lyase activity ; glutamine-phenylpyruvate transaminase activity ; kynurenine-oxoglutarate transaminase activity ; pyridoxal phosphate binding ; transaminase activity ; biosynthetic process ; L-kynurenine catabolic process


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: endoplasmic reticulum ; endoplasmic reticulum membrane ; ceramidase activity ; dihydroceramidase activity ; metal ion binding ; ceramide catabolic process ; sphingosine biosynthetic process


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: chloroplast ; 3'-5' exonuclease activity ; DNA binding ; DNA-directed DNA polymerase activity ; DNA-templated DNA replication ; double-strand break repair


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Input: MLAVALLVLLCASASANSIQSRTSSYSGEYGGKGGKRFSHSGNQLDGPITAFRIRVNRYYIVGLQVRYGTVWSDYVGGTQGDLEEIFLHPGESVIQVSGKYKSYVKQMIFVTDKGRYLPFGKASGTSFNAVPLHPNTVLRFISGRSGSAIDSISLHWDTYPSHCNTC

Output: collagen-containing extracellular matrix ; extracellular space ; Golgi lumen ; mucus layer ; zymogen granule membrane ; carbohydrate binding ; peptidoglycan binding ; defense response to Gram-positive bacterium ; protein transport ; suppression of symbiont entry into host


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: anaphase-promoting complex ; anaphase-promoting complex binding ; ubiquitin ligase activator activity ; anaphase-promoting complex-dependent catabolic process ; cell cycle ; cell division ; positive regulation of anaphase-promoting complex-dependent catabolic process ; protein ubiquitination


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: cytosol ; plasma membrane ; protein-containing complex ; ruffle ; ruffle membrane ; actin binding ; actin filament binding ; guanyl-nucleotide exchange factor activity ; T cell receptor binding ; positive regulation of ruffle assembly ; Rac protein signal transduction ; regulation of Rho protein signal transduction ; Rho protein signal transduction


Instruction: Predict the GO term based on the protein sequence.

Input: MEMKKIACGVLFAAASMTAVMAAEEVGAPAPGPASAASAALPALGSLVGASLVSLFSYYLH

Output: plasma membrane


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Input: MMTPGGSGRLRPLPTAMYAGYSGTASSWVAKTSVSASGKRIQREMAELNIDPPPDCSAGPKGDNLYHWIATIIGPSGTPYEGGIFFLDIIFPSDYPFKPPKLVFKTRIYHCNVDTAGDLSVNILRDSWSPALTITKVLQAIRSIFLKPEPYSPALPVIARLYLTDREKHDEVAKEWTLRFAK

Output: nucleus ; ubiquitin conjugating enzyme activity ; ubiquitin-protein transferase activity ; protein polyubiquitination ; red, far-red light phototransduction ; regulation of photomorphogenesis


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: mitochondrial matrix ; mitochondrion ; ATP binding ; ATP hydrolysis activity ; ATP-dependent peptidase activity ; sequence-specific DNA binding ; serine-type endopeptidase activity ; single-stranded DNA binding ; cellular response to oxidative stress ; chaperone-mediated protein complex assembly ; mitochondrion organization ; oxidation-dependent protein catabolic process ; protein quality control for misfolded or incompletely synthesized proteins


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: core mediator complex ; mediator complex ; nucleus ; transcription coregulator activity ; regulation of transcription by RNA polymerase II ; termination of RNA polymerase II transcription


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: cytosol ; GTPase activator activity ; guanyl-nucleotide exchange factor activity ; actin cytoskeleton organization ; positive regulation of stress fiber assembly ; SREBP signaling pathway


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: centrosome ; early endosome ; late endosome ; lysosome ; midbody ; metal ion binding ; phosphatidylinositol-3-phosphate binding ; protein kinase binding ; autophagosome organization ; double-strand break repair via homologous recombination ; lysosome organization ; mitotic cytokinesis ; regulation of cytokinesis


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: basal plasma membrane ; basolateral plasma membrane ; chloride channel complex ; chloride channel activity ; identical protein binding ; chloride transport ; detection of light stimulus involved in visual perception ; regulation of calcium ion transport ; transepithelial chloride transport


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: cytosol ; DNA binding ; identical protein binding ; mRNA 3'-UTR binding ; NADP binding ; NADPH binding ; NADPH:quinone reductase activity ; zinc ion binding ; protein homotetramerization ; xenobiotic catabolic process


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Input: MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESDLQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQSMQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC

Output: cis-regulatory region sequence-specific DNA binding ; DNA-binding transcription activator activity ; DNA-binding transcription factor activity ; zinc ion binding ; positive regulation of DNA-templated transcription


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: cyanamide hydratase activity ; zinc ion binding ; cyanamide metabolic process


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: cytoplasm ; nucleus ; protein phosphatase 4 complex ; protein phosphatase regulator activity ; meiotic recombination checkpoint signaling ; negative regulation of DNA damage checkpoint


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: D-malate dehydrogenase (decarboxylating) activity ; magnesium ion binding ; NAD binding ; tartrate decarboxylase activity ; tartrate dehydrogenase activity


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: 3-beta-hydroxy-delta5-steroid dehydrogenase activity ; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; defense response to bacterium ; lignin biosynthetic process ; steroid biosynthetic process


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: mRNA cleavage and polyadenylation specificity factor complex ; nucleus ; RNA binding ; mRNA cleavage ; mRNA polyadenylation ; pre-mRNA cleavage required for polyadenylation ; termination of RNA polymerase II transcription, poly(A)-coupled


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: MutSgamma complex ; nuclear chromosome ; nucleus ; ATP binding ; ATP-dependent DNA damage sensor activity ; mismatched DNA binding ; chiasma assembly ; mismatch repair ; reciprocal meiotic recombination


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: cytosol ; adenosylhomocysteinase activity ; one-carbon metabolic process ; S-adenosylhomocysteine catabolic process ; S-adenosylmethionine cycle


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: mediator complex ; transcription coregulator activity ; enteric nervous system development ; interstitial cell of Cajal differentiation ; retinal cone cell development ; thymus development


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: chloroplast ; endosome ; plasma membrane ; GTP binding ; GTPase activity ; protein transport ; regulation of endocytosis ; vesicle-mediated transport


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: nucleus ; DNA-binding transcription factor activity ; transcription cis-regulatory region binding


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: nuclear body ; nucleus ; identical protein binding ; cell cycle ; centriole assembly ; cilium assembly ; motile cilium assembly ; multi-ciliated epithelial cell differentiation ; negative regulation of DNA replication ; positive regulation of transcription by RNA polymerase II ; regulation of cilium assembly ; regulation of DNA-templated DNA replication initiation ; regulation of mitotic cell cycle


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: cytosol ; Golgi apparatus ; plasma membrane ; protein kinase binding ; SH2 domain binding ; adaptive immune response ; antigen receptor-mediated signaling pathway ; B cell activation ; immune response ; intracellular signal transduction ; lymphocyte activation ; negative regulation of MAP kinase activity ; negative regulation of T cell activation


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: DNA ligase IV complex ; nonhomologous end joining complex ; nucleus ; site of double-strand break ; DNA end binding ; DNA polymerase binding ; B cell differentiation ; DNA ligation involved in DNA repair ; double-strand break repair via nonhomologous end joining ; immunoglobulin V(D)J recombination ; response to ionizing radiation ; T cell differentiation


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: centriole ; centrosome ; cytoplasm ; centriole replication ; centriole-centriole cohesion ; positive regulation of establishment of protein localization ; positive regulation of non-motile cilium assembly


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: cytoplasm ; ATP binding ; protein serine kinase activity ; protein serine/threonine kinase activity ; protein phosphorylation


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: metal ion binding ; P-element binding ; transferase activity ; transposase activity ; DNA integration ; transposition, DNA-mediated


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: plasma membrane ; receptor complex ; G protein-coupled receptor activity ; phosphatidylcholine binding ; adenylate cyclase-activating G protein-coupled receptor signaling pathway ; insulin secretion ; regulation of metabolic process


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: chloroplast ; plastid ; beta-carotene isomerase activity ; iron ion binding ; secondary shoot formation ; strigolactone biosynthetic process


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: cytoplasm ; nucleolus ; nucleic acid binding ; rRNA (adenine-N6-)-methyltransferase activity ; S-adenosyl-L-methionine binding ; zinc ion binding ; positive regulation of translation ; rRNA methylation


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Input: MTEAMIRNKPGMASVKDMPLLQDGPPPGGFAPVRYARRISNTGPSAMAMFLAVSGAFAWGMYQVGQGNKIRRALKEEKYAARRTILPILQAEEDERFVSEWKKYLEYEADVMKDVPGWKVGENVYNSGRWMPPATGELRPDVW

Output: extracellular region ; mitochondrial membrane ; mitochondrial respiratory chain complex I ; mitochondrion ; respiratory chain complex I ; embryo development ending in seed dormancy ; photorespiration


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: cytoplasm ; peroxisome ; acyl-CoA dehydrogenase activity ; flavin adenine dinucleotide binding ; fatty acid beta-oxidation using acyl-CoA dehydrogenase ; root hair elongation


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: chloroplast thylakoid ; chloroplast thylakoid membrane ; NAD(P)H dehydrogenase complex (plastoquinone) ; carbohydrate binding ; glucose-6-phosphate 1-epimerase activity ; carbohydrate metabolic process ; photosynthetic electron transport in photosystem I


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: extracellular region ; sperm connecting piece ; myosin light chain binding ; cell differentiation ; motile cilium assembly ; spermatogenesis


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Input: MNQEAASNLGLDLKLNISPSLDSSLLTESSSSSLCSEEAEGGGGEAKSMVVVGCPNCIMYIITSLENDPRCPRCNSHVLLDFLTGNHSKKSTS

Output: ethylene-activated signaling pathway ; regulation of reactive oxygen species metabolic process ; response to salt stress


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: cytosol ; nucleus ; regulation of monopolar cell growth ; unidimensional cell growth


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: nucleus ; DNA-binding transcription factor activity ; transcription cis-regulatory region binding ; ethylene-activated signaling pathway ; gibberellic acid mediated signaling pathway ; positive regulation of seed germination ; response to gibberellin


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: cytoplasm ; L-type voltage-gated calcium channel complex ; synapse ; voltage-gated calcium channel complex ; calcium channel regulator activity ; high voltage-gated calcium channel activity ; calcium ion transmembrane transport via high voltage-gated calcium channel ; chemical synaptic transmission ; neuromuscular junction development ; positive regulation of high voltage-gated calcium channel activity ; regulation of voltage-gated calcium channel activity


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: mitochondrion ; acyl--UDP-N-acetylglucosamine O-acyltransferase activity ; lipid A biosynthetic process ; lipid X metabolic process


Instruction: Predict the GO term based on the protein sequence.

Output: cytoplasm ; early endosome ; Golgi apparatus ; late endosome ; recycling endosome ; vesicle tethering complex ; protein-containing complex binding ; cell differentiation ; collagen fibril organization ; collagen metabolic process ; endosome to lysosome transport ; intracellular protein transport ; peptidyl-lysine hydroxylation ; post-translational protein modification ; spermatogenesis ; vacuolar transport


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: nucleus ; ATP binding ; ATP-dependent chromatin remodeler activity ; DNA binding ; helicase activity ; hydrolase activity ; gene silencing by RNA-directed DNA methylation ; positive regulation of post-transcriptional gene silencing by RNA


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: Golgi apparatus ; membrane ; G protein-coupled receptor activity ; G protein-coupled receptor signaling pathway ; response to molecule of bacterial origin ; root morphogenesis


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: extracellular region ; heme binding ; lactoperoxidase activity ; metal ion binding ; hydrogen peroxide catabolic process ; response to oxidative stress


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: cytosol ; fructose-bisphosphate aldolase activity ; mRNA binding ; fructose 1,6-bisphosphate metabolic process ; gluconeogenesis ; glycolytic process


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Input: MDPGTTGIVGGVSEAKPATPEIQEVADKVKRQLEEKTNEKYEKFKVVEYKSQVVAGQILFMKVDVGNGRFLHMKVLRGLSGDDDLKLLDYQTNKTKNDELTDF

Output: cornified envelope ; cytoplasm ; cytosol ; extracellular space ; peptidase inhibitor complex ; cysteine-type endopeptidase inhibitor activity ; protease binding ; cell-cell adhesion ; keratinocyte differentiation ; negative regulation of peptidase activity ; negative regulation of proteolysis ; peptide cross-linking


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: nucleus ; DNA-binding transcription factor activity, RNA polymerase II-specific ; RNA polymerase II cis-regulatory region sequence-specific DNA binding ; sequence-specific DNA binding ; amnioserosa formation ; compound eye development ; positive regulation of transcription by RNA polymerase II ; regulation of transcription by RNA polymerase II


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: cytosol ; nucleoplasm ; nucleus ; proteasome complex ; proteasome core complex ; proteasome core complex, beta-subunit complex ; proteasome-mediated ubiquitin-dependent protein catabolic process


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: plant-type cell wall ; vacuole ; hydrolase activity ; strictosidine synthase activity ; alkaloid metabolic process ; biosynthetic process


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: nucleolus ; nucleus ; RNA polymerase I upstream activating factor complex ; RNA polymerase I general transcription initiation factor activity ; chromatin organization ; nucleolar large rRNA transcription by RNA polymerase I ; positive regulation of transcription by RNA polymerase I


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Input: MIFKRAVSTLIPPKVVSSKNIGSAPNAKRIANVVHFYKSLPQGPAPAIKANTRLARYKAKYFDGDNASGKPLWHFALGIIAFGYSMEYYFHLRHHKGAEEH

Output: mitochondrial inner membrane ; mitochondrial proton-transporting ATP synthase complex ; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; mitochondrion ; proton motive force-driven ATP synthesis ; proton transmembrane transport


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: Atg1/ULK1 kinase complex ; cytosol ; mitochondrion ; phagophore assembly site ; protein kinase binding ; autophagosome assembly ; mitophagy ; negative regulation of cell population proliferation ; piecemeal microautophagy of the nucleus ; positive regulation of autophagy ; protein autophosphorylation ; protein localization to phagophore assembly site ; regulation of protein lipidation ; response to mitochondrial depolarisation


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Input: MSSRRSRSRQSGSSRITDEQISDLVSKLQDLLPEARLRSNDRVPSSRVLQETCNYIRSLHQEVDDLSERLSELLATSDMSSAQAAIIRSLLM

Output: nucleus ; protein dimerization activity ; brassinosteroid mediated signaling pathway ; regulation of DNA-templated transcription ; regulation of seed growth


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Input: MQIITTTFIQKVILGSHQLHEQLSIVEARMIESAIVSMLTESFCENEQTLKYLARLLSPMSYMDVINARRGKKICGYPLCYKSAAENSSDGFFIHSMYCNNYHSKCSLYLMRQLSQTPLHERRGVHLTSYINLEFDDMYSVSLLEELVGSEVPIDTVKSLITSFKDLEFDDTYKNEPLPLDVYFGQLTTDEETCIE

Output: cytoplasm ; nucleus ; metal ion binding ; myosin phosphatase activity ; RNA polymerase core enzyme binding ; RNA polymerase II CTD heptapeptide repeat phosphatase activity


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Input: MMNFEVSTTKQIGVGLTTFGFFFIFLGVLMFLDSALLAIGNLLFIVGITFIIGVQRTLVFFFEFRKLKGSILFFGGILVVLFGYPLFGMIAECWGFIVLFGGFLPGIVNLLRSIPGISTITYLPGIRQVLDRLAPESKYPV

Output: cytosol ; endoplasmic reticulum ; Golgi membrane ; membrane ; endoplasmic reticulum to Golgi vesicle-mediated transport ; protein transport ; retrograde transport, endosome to Golgi


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: nuclear speck ; nucleus ; ribonucleoprotein complex ; mRNA binding ; developmental process ; in utero embryonic development ; mRNA processing ; regulation of alternative mRNA splicing, via spliceosome ; RNA splicing


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: endosome ; Golgi apparatus ; membrane ; trans-Golgi network ; sodium:potassium:chloride symporter activity


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Input: MAAEEGQVIGCHTNDVWTVQLDKAKESNKLIVIDFTASWCPPCRMIAPIFNDLAKKFMSSAIFFKVDVDELQSVAKEFGVEAMPTFVFIKAGEVVDKLVGANKEDLQAKIVKHTGVTTA

Output: cytosol ; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor ; protein-disulfide reductase activity


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: cyclin-dependent protein kinase holoenzyme complex ; mediator complex ; nucleoplasm ; nucleus ; ubiquitin ligase complex ; cyclin-dependent protein serine/threonine kinase regulator activity ; identical protein binding ; ubiquitin protein ligase activity ; G0 to G1 transition ; negative regulation of Notch signaling pathway ; negative regulation of triglyceride metabolic process ; positive regulation of transcription by RNA polymerase II ; protein ubiquitination


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: nucleus ; DNA binding ; DNA-binding transcription factor activity ; positive regulation of DNA-templated transcription ; response to auxin ; response to ethylene ; response to gibberellin ; response to sucrose


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: cytoplasm ; cytosol ; nucleus ; ubiquitin conjugating enzyme binding ; ubiquitin protein ligase activity ; ubiquitin-protein transferase activity ; zinc ion binding ; neuron apoptotic process ; proteasome-mediated ubiquitin-dependent protein catabolic process ; protein ubiquitination ; ubiquitin-dependent protein catabolic process


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: nucleus ; mRNA binding ; erythrocyte maturation ; mRNA processing ; negative regulation of mRNA splicing, via spliceosome ; negative regulation of RNA splicing ; regulation of cell differentiation ; regulation of RNA splicing ; RNA splicing


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: COPII-coated ER to Golgi transport vesicle ; endoplasmic reticulum membrane ; endoplasmic reticulum-Golgi intermediate compartment ; endoplasmic reticulum-Golgi intermediate compartment membrane ; Golgi apparatus ; Golgi membrane ; intracellular membrane-bounded organelle ; endoplasmic reticulum to Golgi vesicle-mediated transport ; protein transport


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: nucleus ; myosin phosphatase activity ; RNA polymerase II CTD heptapeptide repeat phosphatase activity ; negative regulation of transcription by RNA polymerase II ; oogenesis


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: cytoplasm ; nucleus ; stigma papilla ; ATP binding ; protein serine kinase activity ; protein serine/threonine kinase activity ; endocytosis ; peptidyl-serine phosphorylation ; signal transduction


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: cytosol ; nucleoplasm ; nucleus ; transcription coactivator activity ; negative regulation of cell growth ; positive regulation of DNA-templated transcription


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: cytoplasm ; ATP binding ; GTP binding ; uracil phosphoribosyltransferase activity ; uridine kinase activity ; CTP salvage ; phosphorylation ; UMP salvage


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Input: MESIWRIATGQDPSREDYEGIEFWSNPERSGWLTKQGDYIKTWRRRWFVLKRGKLLWFKDQAAAGIRGSTPRGVISVGDCLTVKGAEDVVNKPFAFELSSGSYTMFFIADNEKEKEEWINSIGRSIVQHSRSVTDSEVLDYDHRR

Output: cytosol ; early endosome ; peroxisome ; recycling endosome ; trans-Golgi network ; phosphatidylinositol-3-phosphate binding ; endosome organization ; receptor recycling ; retrograde transport, endosome to Golgi


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Input: MASKNSASLALFFALNILFFTLTAGTNCRCNPSPKPRPLPNPKVPSPKVPTPSVPSPYVPTPSVPSPSVPTPSVPSPSVPSPNPTPVIPPRTPGSSGNCPIDALRLGVCANVLSGLLNVQLGQPSPQPCCSLIQGLVDLDAAVCLCTALRANVLGINLNVPISLSVLLNVCNRRLPSNFQCA

Output: chloroplast outer membrane ; endoplasmic reticulum ; extracellular region ; plasmodesma ; defense response to fungus


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: cytoplasm ; meiotic spindle ; microtubule ; protein-containing complex ; spindle ; spindle pole ; microtubule binding ; cell cycle ; cell division


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: endosome ; endosome membrane ; lysosomal membrane ; lysosome ; arachidonic acid binding ; potassium channel activity ; potassium ion leak channel activity ; proton channel activity ; lysosomal lumen pH elevation ; neuron cellular homeostasis ; phagosome-lysosome fusion ; potassium ion transmembrane transport ; proton transmembrane transport ; regulation of lysosomal lumen pH


Instruction: Predict the GO term based on the protein sequence.

Output: plasma membrane ; positive regulation of adenylate cyclase activity


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: nucleus ; DNA-binding transcription factor activity ; transcription cis-regulatory region binding ; cell division ; ethylene-activated signaling pathway ; induced systemic resistance, jasmonic acid mediated signaling pathway ; phloem or xylem histogenesis ; positive regulation of DNA-templated transcription


Instruction: Predict the GO term based on the protein sequence.

Output: adherens junction ; membrane ; identical protein binding ; metal ion binding ; protein-glutamine gamma-glutamyltransferase activity ; animal organ morphogenesis ; keratinization ; keratinocyte differentiation ; peptide cross-linking ; positive regulation of cell cycle ; positive regulation of keratinocyte proliferation


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: cytoplasm ; cytosol ; ATP binding ; xylulokinase activity ; D-xylose metabolic process ; phosphorylation ; xylulose catabolic process ; xylulose metabolic process


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: DNA binding ; DNA-binding transcription factor activity ; sequence-specific DNA binding ; DNA damage response ; DNA-templated transcription ; regulation of DNA-templated transcription


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Input: MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRNRERGPVAI

Output: cytoplasm ; protein flavinylation ; respiratory chain complex II assembly ; succinate metabolic process


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: cytoplasm ; eukaryotic translation initiation factor 2 complex ; synapse ; GTP binding ; GTPase activity ; translation factor activity, RNA binding ; translation initiation factor activity ; tRNA binding ; formation of translation preinitiation complex ; translational initiation


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: nucleus ; metal ion binding ; abaxial cell fate specification ; cell fate commitment ; fruit development ; polarity specification of adaxial/abaxial axis ; regulation of leaf development ; regulation of shoot apical meristem development


Instruction: Predict the GO term based on the protein sequence.

Output: cytoplasm ; cytosol ; mitochondrial inner membrane ; mitochondrial matrix ; mitochondrion ; nucleus ; thymidylate synthase activity ; dTMP biosynthetic process ; dTTP biosynthetic process ; methylation


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Input: MSFCSFFGGEVFQNHFEPGVYVCAKCGYELFSSRSKYAHSSPWPAFTETIHEDSVAKCPEKNRPEALKVSCGKCGNGLGHEFLNDGPKRGQSRFUIFSSSLKFIPKGKEAPASQGD

Output: actin cytoskeleton ; cytoplasm ; nucleus ; actin binding ; L-methionine-(R)-S-oxide reductase activity ; methionine-R-sulfoxide reductase activity ; peptide-methionine (R)-S-oxide reductase activity ; zinc ion binding ; actin filament polymerization ; innate immune response ; protein repair


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: cytoplasm ; extracellular region ; serine-type endopeptidase activity ; proteolysis


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: anchoring junction ; apical plasma membrane ; basolateral plasma membrane ; endoplasmic reticulum membrane ; neuromuscular junction ; neuron projection ; postsynaptic density membrane ; phosphatase binding ; actin filament organization ; cell-cell adhesion ; chemical synaptic transmission ; cortical actin cytoskeleton organization ; endothelial cell proliferation ; negative regulation of G1/S transition of mitotic cell cycle ; neurotransmitter receptor localization to postsynaptic specialization membrane ; synapse organization


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: cytosol ; mitochondrial membrane ; plasma membrane ; ATP binding ; kinase activity ; cerebellar Purkinje cell layer morphogenesis ; phosphorylation ; ubiquinone biosynthetic process


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: cytoplasm ; mitochondrial intermembrane space ; nucleus ; 2 iron, 2 sulfur cluster binding ; 4 iron, 4 sulfur cluster binding ; electron transfer activity ; metal ion binding ; apoptotic process ; hemopoiesis ; iron-sulfur cluster assembly ; negative regulation of apoptotic process


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: cytoplasm ; cytoskeleton ; plasma membrane ; voltage-gated potassium channel complex ; potassium channel activator activity ; potassium channel regulator activity ; transmembrane transporter binding ; voltage-gated potassium channel activity ; positive regulation of voltage-gated potassium channel activity ; potassium ion transmembrane transport


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: plasma membrane ; G protein-coupled receptor activity ; response to amino acid


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: nuclear envelope ; nuclear membrane


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: nuclear exosome (RNase complex) ; nucleolus ; nucleoplasm ; nucleus ; preribosome, large subunit precursor ; blastocyst formation ; ribosomal large subunit biogenesis ; RNA metabolic process ; rRNA processing


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Input: MAGSGRDDPLVVGRIVGDVLDPFVRITNLSVSYGARIVSNGCELKPSMVTQQPRVVVGGNDMRTFYTLVMVDPDAPSPSNPNLREYLHWLVTDIPGTTGATFGQEVMCYESPRPTMGIHRLVFVLFQQLGRQTVYAPGWRQNFSTRNFAELYNLGSPVATVYFNCQREAGSGGRRVYP

Output: endoplasmic reticulum ; nucleus ; cell differentiation ; flower development ; inflorescence development ; photoperiodism, flowering ; regulation of flower development ; regulation of timing of transition from vegetative to reproductive phase ; vegetative to reproductive phase transition of meristem


Instruction: Predict the GO term based on the protein sequence.

Output: chloroplast ; chloroplast stroma


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: mitochondrial inner membrane ; mitochondrial large ribosomal subunit ; mitochondrion ; nuclear body ; nucleoplasm ; plasma membrane ; double-stranded RNA binding ; ribonuclease III activity ; structural constituent of ribosome ; mitochondrial translation ; mitochondrial translational elongation ; rRNA processing


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: nucleus ; methyl-CpG binding


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: chloroplast ; arogenate dehydrogenase (NADP+) activity ; NAD+ binding ; prephenate dehydrogenase (NAD+) activity ; prephenate dehydrogenase (NADP+) activity ; tyrosine biosynthetic process


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: cytoplasm ; nucleus ; DNA-binding transcription factor activity ; RNA polymerase II cis-regulatory region sequence-specific DNA binding ; regulation of transcription by RNA polymerase II


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: synaptic vesicle membrane ; heart development ; intracellular calcium ion homeostasis ; T-tubule organization


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: cytosol ; pyridoxal phosphate binding ; threonine synthase activity ; threonine biosynthetic process


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Input: MTYRCLLPMVLLLCFSTTALSRSYSLLRFQQRRSAEVCQKLLGQLHSTPQHCLEAKMDFQVPEEMNQAQQFRKEDAILVIYEMLQQIFNILTRDFSSTGWSETIIEDLLVELYGQMNRLQPIQKEIMQEQNFTMGDTTVLHLKKYYFNLVQYLESKEYNRCAWTVVRVQILTNFSFLMRLTASLRD

Output: extracellular space ; cytokine activity ; type I interferon receptor binding ; adaptive immune response ; B cell differentiation ; B cell proliferation ; cytokine-mediated signaling pathway ; defense response to virus ; humoral immune response ; natural killer cell activation involved in immune response ; positive regulation of peptidyl-serine phosphorylation of STAT protein ; response to exogenous dsRNA ; T cell activation involved in immune response


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: cytoplasm ; nucleus ; ATP binding ; chromatin binding ; regulation of transcription by RNA polymerase II ; tRNA modification ; tRNA wobble uridine modification


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: plasma membrane ; transmembrane transporter activity ; aldonate transmembrane transport ; carbohydrate transport


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: cytoplasm ; cytosol ; 3'-phosphoadenosine 5'-phosphosulfate binding ; alcohol sulfotransferase activity ; bile-salt sulfotransferase activity ; steroid sulfotransferase activity ; sulfotransferase activity ; 3'-phosphoadenosine 5'-phosphosulfate metabolic process ; cholesterol metabolic process ; ethanol catabolic process ; steroid metabolic process ; sulfation ; thyroid hormone metabolic process ; xenobiotic metabolic process


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: aminopeptidase activity ; metal ion binding ; metalloaminopeptidase activity ; metallopeptidase activity ; proteolysis


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Input: MPMFVVNTNVPRASVPDGLLSELTQQLAQATGKPAQYIAVHVVPDQLMTFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLTERLRISPDRIYINFCDMNAANVGWNGSTFA

Output: cytoplasm ; extracellular space ; cytokine activity ; dopachrome isomerase activity ; phenylpyruvate tautomerase activity ; inflammatory response ; innate immune response


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: cytoplasm ; nucleus ; ubiquitin protein ligase activity ; zinc ion binding ; protein ubiquitination ; ubiquitin-dependent protein catabolic process


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: cell periphery ; extracellular region ; fungal-type cell wall ; fungal-type vacuole ; membrane ; structural constituent of cell wall ; fungal-type cell wall organization


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: early endosome ; extracellular space ; plasma membrane ; recycling endosome ; ferric iron binding ; antibacterial humoral response ; intracellular iron ion homeostasis ; iron ion transmembrane transport ; iron ion transport


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: membrane ; fatty acid alpha-hydroxylase activity ; heme binding ; iron ion binding ; monooxygenase activity ; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; brassinosteroid biosynthetic process ; brassinosteroid homeostasis ; sterol metabolic process


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: cytoplasm ; nucleus ; ATP binding ; MAP kinase activity ; protein serine kinase activity ; protein serine/threonine kinase activity ; cell cycle ; intracellular signal transduction ; protein phosphorylation


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: mitochondrion ; alcohol dehydrogenase (NAD+) activity ; hydroxyacid-oxoacid transhydrogenase activity ; metal ion binding ; glutamate catabolic process via 2-oxoglutarate ; lipid metabolic process


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: endosome ; endosome membrane ; pathogen-containing vacuole ; ATP binding ; ATP hydrolysis activity ; endosomal transport ; protein transport ; response to bacterium ; response to wounding ; vacuole organization


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: cytosol ; nuclear replication fork ; nucleoplasm ; protein serine/threonine kinase activator activity ; DNA damage response ; DNA repair ; positive regulation of protein serine/threonine kinase activity ; regulation of DNA damage checkpoint ; replication fork processing


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: identical protein binding ; isotype switching


Instruction: Predict the GO term based on the protein sequence.

Input: MAAAAEDVEFVDYDRDEEEEEDAMDEDDRGGGRGGRALPVPHIVSQGVMRSRGRLLGRSTSVLASNRDRFDSLADAGNPGHGPQRSIEGWILLVSGVKEDAEEDDLYNTFSDFGHVKDLHLNLERRTGYAKGYALVEYESFEEAQTAIKAMNGTQLLTRTVYVDWAFSRGPIQKLTSTRPLHRRSRTPPRRLAALTC

Output: cytoplasm ; exon-exon junction complex ; mRNA binding ; mRNA processing ; mRNA transport ; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; regulation of translation ; RNA splicing


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: cytosol ; extracellular region ; Golgi apparatus ; heparin binding ; angiogenesis ; hematopoietic stem cell differentiation ; positive regulation of canonical Wnt signaling pathway ; positive regulation of Wnt signaling pathway ; vascular endothelial growth factor receptor signaling pathway ; Wnt signaling pathway


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: cytosol ; nucleolus ; small-subunit processome ; cell differentiation ; meiotic cell cycle ; rRNA processing ; spermatogenesis


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: extracellular space ; calcium ion binding ; peptidase activity ; serine-type endopeptidase activity ; proteolysis ; response to bleomycin


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: cytoplasm ; Atg8-specific peptidase activity ; cysteine-type peptidase activity ; autophagy ; lipid metabolic process ; protein delipidation ; protein transport ; proteolysis


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: plasma membrane ; aminoacetone:oxygen oxidoreductase(deaminating) activity ; copper ion binding ; phenethylamine:oxygen oxidoreductase (deaminating) activity ; primary amine oxidase activity ; quinone binding ; tryptamine:oxygen oxidoreductase (deaminating) activity ; amine metabolic process ; catecholamine metabolic process


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: nucleus ; DNA-binding transcription factor activity ; minor groove of adenine-thymine-rich DNA binding ; protein self-association ; defense response to bacterium ; innate immune response ; negative regulation of defense response to bacterium ; negative regulation of innate immune response ; regulation of photoperiodism, flowering


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: mitochondrion ; succinate-CoA ligase complex (ADP-forming) ; copper ion binding ; nucleotide binding ; succinate-CoA ligase (ADP-forming) activity ; succinate-CoA ligase (GDP-forming) activity ; tricarboxylic acid cycle


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: mitochondrion ; ATP binding ; tetraacyldisaccharide 4'-kinase activity ; lipid A biosynthetic process ; lipid X metabolic process ; phosphorylation


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: chloroplast ; chloroplast envelope ; chloroplast stroma ; plastid ; mRNA binding ; peptidyl-prolyl cis-trans isomerase activity ; protein folding chaperone ; ribosome binding ; 'de novo' cotranslational protein folding ; chaperone-mediated protein folding ; protein transport ; protein unfolding


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: motile cilium ; outer dense fiber ; plasma membrane ; cell differentiation ; spermatogenesis


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: cytoplasm ; membrane ; metal ion binding ; olfactory receptor binding ; defense response to virus ; detection of chemical stimulus involved in sensory perception of bitter taste ; protein insertion into membrane ; protein targeting to membrane


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: mitochondrial membrane ; mitochondrion ; abscisic acid-activated signaling pathway ; mitochondria-nucleus signaling pathway ; mitochondrion organization


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: cytoplasm ; cytosol ; glutathione transferase activity ; glutathione metabolic process ; toxin catabolic process