Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: plasma membrane ; signaling receptor binding ; zinc ion binding ; antibacterial humoral response ; defense response to other organism ; determination of adult lifespan ; innate immune response ; negative regulation of immune response ; negative regulation of peptidoglycan recognition protein signaling pathway ; response to bacterium


GO Terms Prediction

Instruction: Predict the GO term based on the protein sequence.

Output: cell surface ; dendrite ; GABA-ergic synapse ; glutamatergic synapse ; nucleoplasm ; phagocytic vesicle ; plasma membrane ; postsynaptic specialization, intracellular component ; palmitoyltransferase activity ; protein-cysteine S-palmitoyltransferase activity ; innate immune response ; lipid transport ; positive regulation of pattern recognition receptor signaling pathway ; positive regulation of protein localization to phagocytic vesicle ; positive regulation of protein localization to plasma membrane ; protein palmitoylation ; regulation of postsynaptic membrane neurotransmitter receptor levels


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: cell projection ; cytoplasm ; cytosol ; presynapse ; calcium channel regulator activity ; calcium ion binding ; transmembrane transporter binding ; photoreceptor cell morphogenesis ; phototransduction ; regulation of voltage-gated calcium channel activity ; retinal bipolar neuron differentiation ; retinal cone cell development ; visual perception


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: cytoplasm ; nucleus ; metal ion binding ; protein homodimerization activity ; ubiquitin protein ligase activity ; positive regulation of response to water deprivation ; protein ubiquitination ; regulation of autophagosome assembly ; ubiquitin-dependent protein catabolic process


Instruction: Predict the GO term based on the protein sequence.

Output: plasma membrane ; plasmodesma ; sucrose-phosphate synthase activity ; nectar secretion ; sucrose biosynthetic process


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: cytoplasm ; extracellular space ; membrane ; photoreceptor outer segment ; plasma membrane ; stereocilium ; synapse ; calcium ion binding ; actin filament organization ; adult walking behavior ; auditory receptor cell stereocilium organization ; cell adhesion ; detection of mechanical stimulus involved in equilibrioception ; detection of mechanical stimulus involved in sensory perception of sound ; equilibrioception ; homophilic cell adhesion via plasma membrane adhesion molecules ; inner ear auditory receptor cell differentiation ; inner ear development ; inner ear receptor cell stereocilium organization ; locomotory behavior ; morphogenesis of an epithelium ; multicellular organism growth ; non-motile cilium assembly ; photoreceptor cell maintenance ; response to calcium ion ; righting reflex ; sensory perception of light stimulus ; sensory perception of sound ; startle response ; visual perception


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: cytosol ; nucleus ; SCF ubiquitin ligase complex ; photoreceptor activity ; circadian rhythm ; flower development ; negative regulation of cellulose biosynthetic process ; positive regulation of flower development ; protein ubiquitination ; regulation of DNA-templated transcription ; regulation of gene expression ; response to blue light


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: centrosome ; ciliary basal body ; cytosol ; Golgi apparatus ; neuron projection ; nucleoplasm ; nucleus ; perinuclear region of cytoplasm ; plasma membrane ; spindle ; spindle microtubule ; ATP binding ; kinase activity ; protein kinase activity ; protein serine kinase activity ; protein serine/threonine kinase activity ; tau-protein kinase activity ; circadian regulation of gene expression ; endocytosis ; Golgi organization ; microtubule nucleation ; non-motile cilium assembly ; peptidyl-serine phosphorylation ; positive regulation of canonical Wnt signaling pathway ; positive regulation of non-canonical Wnt signaling pathway ; positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; positive regulation of protein phosphorylation ; positive regulation of Wnt signaling pathway ; positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation ; protein localization to centrosome ; protein localization to cilium ; protein localization to Golgi apparatus ; protein phosphorylation ; regulation of circadian rhythm ; signal transduction ; spindle assembly ; Wnt signaling pathway


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: extracellular space ; serine-type carboxypeptidase activity ; brassinosteroid mediated signaling pathway ; proteolysis


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: endoplasmic reticulum lumen ; endoplasmic reticulum membrane ; calcium ion binding ; carbohydrate binding ; unfolded protein binding ; protein folding ; ubiquitin-dependent ERAD pathway


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: B-WICH complex ; condensed chromosome ; nuclear replication fork ; nucleolus ; nucleoplasm ; nucleus ; pericentric heterochromatin ; WICH complex ; ATP binding ; histone binding ; histone H2AY142 kinase activity ; histone kinase activity ; metal ion binding ; protein tyrosine kinase activity ; chromatin organization ; chromatin remodeling ; DNA damage response ; negative regulation of mitotic chromosome condensation ; phosphorylation ; positive regulation of histone acetylation ; positive regulation of transcription by RNA polymerase I ; positive regulation of transcription by RNA polymerase II ; positive regulation of transcription by RNA polymerase III ; post-translational protein modification


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: neuron projection ; plasma membrane ; G protein-coupled receptor activity ; prostaglandin D receptor activity ; prostaglandin F receptor activity ; prostaglandin J receptor activity ; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway ; calcium-mediated signaling ; chemotaxis ; G protein-coupled receptor signaling pathway ; negative regulation of male germ cell proliferation ; neuropeptide signaling pathway ; positive regulation of G protein-coupled receptor signaling pathway


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: chloroplast ; chloroplast stroma ; cytoplasm ; cytosol ; mitochondrion ; plant-type vacuole ; plasma membrane ; glutathione binding ; glutathione transferase activity ; peroxidase activity ; cellular response to water deprivation ; glutathione metabolic process ; response to oxidative stress ; toxin catabolic process


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: Cdc73/Paf1 complex ; nucleolus ; RNA polymerase II C-terminal domain phosphoserine binding ; single-stranded DNA binding ; blastocyst growth ; endodermal cell fate commitment ; negative regulation of transcription by RNA polymerase II ; stem cell population maintenance ; transcription elongation by RNA polymerase II ; Wnt signaling pathway


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: axoneme ; ciliary base ; cilium movement ; determination of left/right symmetry ; heart development ; outer dynein arm assembly ; regulation of cilium beat frequency ; ventricular system development


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: actin cytoskeleton ; cytoplasm ; cytosol ; ATP binding ; calmodulin-dependent protein kinase activity ; myosin light chain kinase activity ; cardiac myofibril assembly ; cellular response to interleukin-1 ; positive regulation of sarcomere organization ; protein phosphorylation ; regulation of vascular permeability involved in acute inflammatory response ; sarcomere organization ; sarcomerogenesis


Instruction: Predict the GO term based on the protein sequence.

Output: Golgi membrane ; acetylglucosaminyltransferase activity ; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity ; inter-male aggressive behavior ; kidney morphogenesis ; neutrophil homeostasis ; protein glycosylation ; thyroid hormone metabolic process ; tissue morphogenesis


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: cytoplasmic vesicle membrane ; Golgi membrane ; plasma membrane ; transport vesicle membrane ; metal ion binding ; metalloendopeptidase activity ; brain development ; cardioblast differentiation ; heart development ; peptide hormone processing ; protein processing


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: chloroplast ; cytoplasm ; cytosol ; indole-3-glycerol-phosphate lyase activity ; tryptophan synthase activity ; auxin biosynthetic process ; tryptophan biosynthetic process


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Input: MPPKTSGKAAKKAGKAQKNITKTDKKKKRKRKESYAIYIYKVLKQVHPDTGISSKAMSIMNSFVNDIFERIAAEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK

Output: nucleosome ; nucleus ; DNA binding ; protein heterodimerization activity ; protein-containing complex binding ; structural constituent of chromatin ; chromatin organization


Instruction: Predict the GO term based on the protein sequence.

Output: mitochondrial inner membrane ; mitochondrial matrix ; mitochondrion ; 5-aminolevulinate synthase activity ; identical protein binding ; pyridoxal phosphate binding ; cellular response to insulin stimulus ; cellular response to organic cyclic compound ; erythrocyte development ; heme biosynthetic process ; hemoglobin biosynthetic process ; protoporphyrinogen IX biosynthetic process ; response to bile acid ; response to cAMP ; response to cobalt ion ; response to ethanol ; response to gonadotropin ; response to herbicide ; response to hypoxia ; response to nickel cation ; response to nutrient levels ; response to organic cyclic compound ; response to organic substance ; response to platinum ion ; response to xenobiotic stimulus


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: cytoplasm ; DNA binding ; phosphorelay signal transduction system ; positive regulation of DNA-templated transcription


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: chromosome, telomeric region ; cytoplasm ; nucleus ; SCF ubiquitin ligase complex ; ATP binding ; ubiquitin conjugating enzyme activity ; ubiquitin-protein transferase activity ; cell division ; cellular response to methylmercury ; DNA replication ; G1/S transition of mitotic cell cycle ; G2/M transition of mitotic cell cycle ; mitochondrial fusion ; mitotic intra-S DNA damage checkpoint signaling ; positive regulation of glucose transmembrane transport ; proteasome-mediated ubiquitin-dependent protein catabolic process ; protein autoubiquitination ; protein polyubiquitination ; regulation of metabolic process ; regulation of mitotic cell cycle ; regulation of sulfur amino acid metabolic process ; regulation of transcription by galactose ; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; silent mating-type cassette heterochromatin formation ; subtelomeric heterochromatin formation ; ubiquitin-dependent protein catabolic process


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: nucleus ; RNA polymerase II transcription regulator complex ; DNA-binding transcription activator activity, RNA polymerase II-specific ; DNA-binding transcription factor activity, RNA polymerase II-specific ; RNA polymerase II cis-regulatory region sequence-specific DNA binding ; RNA polymerase II transcription regulatory region sequence-specific DNA binding ; sequence-specific double-stranded DNA binding ; liver development ; positive regulation of transcription by RNA polymerase II ; regulation of transcription by RNA polymerase II ; rhythmic process


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: extracellular region ; extracellular matrix structural constituent ; cell adhesion ; collagen fibril organization ; negative regulation of cell population proliferation


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: cytoplasm ; messenger ribonucleoprotein complex ; muscle cell postsynaptic specialization ; neuromuscular junction ; neuronal ribonucleoprotein granule ; nuclear envelope ; nucleus ; postsynapse ; type Ib terminal bouton ; type Is terminal bouton ; CCR4-NOT complex binding ; mRNA 3'-UTR binding ; mRNA regulatory element binding translation repressor activity ; RNA binding ; sequence-specific mRNA binding ; anterior/posterior axis specification, embryo ; behavioral response to ethanol ; cell migration ; chemical synaptic transmission ; dendrite morphogenesis ; germ cell development ; head involution ; long-term memory ; mitotic cell cycle ; modulation of chemical synaptic transmission ; negative regulation of cell cycle ; negative regulation of DNA-templated transcription ; negative regulation of epidermal growth factor receptor signaling pathway ; negative regulation of translation ; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; oogenesis ; pole cell migration ; positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA ; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; positive regulation of translation ; post-transcriptional gene silencing ; post-transcriptional regulation of gene expression ; regulation of synaptic assembly at neuromuscular junction


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: cytoplasm ; endoplasmic reticulum lumen ; endoplasmic reticulum membrane ; calcium ion binding ; carbohydrate binding ; unfolded protein binding ; defecation ; endoplasmic reticulum unfolded protein response ; hemidesmosome assembly ; multicellular organismal reproductive process ; negative regulation of oxidative stress-induced neuron death ; programmed cell death ; protein folding ; regulation of gene expression ; response to ethanol ; response to heat ; ubiquitin-dependent ERAD pathway


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: endoplasmic reticulum ; mitochondrion ; nucleus ; DNA-binding transcription factor activity ; DNA-binding transcription factor activity, RNA polymerase II-specific ; Hsp70 protein binding ; RNA polymerase II cis-regulatory region sequence-specific DNA binding ; RNA polymerase II transcription regulatory region sequence-specific DNA binding ; sequence-specific DNA binding ; cell fate specification ; defense response to Gram-negative bacterium ; determination of adult lifespan ; digestive tract development ; embryonic digestive tract development ; embryonic pattern specification ; endodermal cell fate specification ; mesendoderm development ; negative regulation of neuron death ; positive regulation of cellular response to manganese ion ; positive regulation of cellular response to oxidative stress ; positive regulation of gene expression ; positive regulation of transcription by RNA polymerase II ; positive regulation of transcription from RNA polymerase II promoter in response to heat stress ; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response ; regulation of gene expression ; regulation of transcription by RNA polymerase II ; regulation of translation ; response to heat ; response to oxidative stress ; response to paraquat ; response to superoxide


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: cell surface ; neuronal cell body ; plasma membrane ; synapse ; identical protein binding ; PDZ domain binding ; cell migration ; dendrite morphogenesis ; regulation of dendrite morphogenesis ; response to caffeine ; response to hypoxia ; wound healing


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: extracellular region ; metal ion binding ; metalloendopeptidase activity ; proteolysis


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: cytoplasm ; cytosol ; neuromuscular junction ; nucleus ; ATP binding ; DNA-binding transcription factor binding ; MAP kinase activity ; protein kinase binding ; protein serine kinase activity ; protein serine/threonine kinase activity ; behavioral response to ethanol ; branching involved in open tracheal system development ; cell surface receptor signaling pathway ; cellular response to arsenic-containing substance ; cellular response to cadmium ion ; cellular response to reactive oxygen species ; cellular response to starvation ; defense response to virus ; determination of adult lifespan ; dorsal appendage formation ; epidermal growth factor receptor signaling pathway ; ERK1 and ERK2 cascade ; fibroblast growth factor receptor signaling pathway ; imaginal disc-derived wing morphogenesis ; imaginal disc-derived wing vein specification ; insulin receptor signaling pathway ; intracellular signal transduction ; leg disc proximal/distal pattern formation ; lymph gland crystal cell differentiation ; lymph gland plasmatocyte differentiation ; MAPK cascade ; metamorphosis ; mitotic cell cycle ; modulation of chemical synaptic transmission ; negative regulation of macroautophagy ; positive regulation of cell population proliferation ; positive regulation of cell size ; positive regulation of DNA-binding transcription factor activity ; positive regulation of photoreceptor cell differentiation ; positive regulation of wound healing ; protein phosphorylation ; R7 cell fate commitment ; regulation of heart morphogenesis ; regulation of response to drug ; sevenless signaling pathway ; terminal branching, open tracheal system ; terminal region determination ; torso signaling pathway ; tracheal pit formation in open tracheal system ; vascular endothelial growth factor receptor signaling pathway


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: malonate-semialdehyde dehydrogenase (acetylating) activity ; malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity ; methylmalonate-semialdehyde dehydrogenase (acylating) activity ; inositol catabolic process ; thymine catabolic process ; valine catabolic process


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: chromosome, telomeric region ; cytoplasm ; cytosol ; EKC/KEOPS complex ; nucleoplasm ; nucleus ; ATP binding ; ATP hydrolysis activity ; protein serine kinase activity ; protein serine/threonine kinase activity ; cellular bud site selection ; maintenance of translational fidelity ; positive regulation of transcription by RNA polymerase II ; protein phosphorylation ; telomere maintenance ; telomere maintenance via recombination ; tRNA threonylcarbamoyladenosine metabolic process ; tRNA threonylcarbamoyladenosine modification


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Input: MSFLPSFILSDESKERISKILTLTHNVAHYGWIPFVLYLGWAHTSNRPNFLNLLSPLPSV

Output: mitochondrial outer membrane ; mitochondrial outer membrane translocase complex ; mitochondrion ; protein import into mitochondrial matrix ; protein insertion into mitochondrial outer membrane


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: chromatin ; nucleosome ; nucleus ; protein-DNA complex ; chromatin DNA binding ; DNA binding ; double-stranded DNA binding ; molecular adaptor activity ; nucleic acid binding ; nucleosomal DNA binding ; phosphate ion binding ; structural constituent of chromatin ; supercoiled DNA binding ; chromosome condensation ; negative regulation of DNA recombination ; nucleosome assembly ; regulation of DNA-templated transcription


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: cytoplasm ; fungal-type vacuole membrane ; membrane ; PAS complex ; vacuolar membrane ; 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process ; positive regulation of kinase activity ; positive regulation of phosphatidylinositol biosynthetic process ; protein localization to vacuolar membrane ; regulation of phosphatidylinositol biosynthetic process ; vacuole inheritance


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: actin filament ; cell body ; cytoplasm ; filopodium ; glutamatergic synapse ; I band ; lamellipodium ; sarcomere ; synapse ; ATP binding ; hydrolase activity ; microfilament motor activity ; myosin binding ; actin filament organization ; actin filament-based movement ; actin-mediated cell contraction ; actin-myosin filament sliding ; actomyosin structure organization ; cardiac muscle contraction ; cardiac muscle tissue morphogenesis ; cardiac myofibril assembly ; heart contraction ; mesenchyme migration ; negative regulation of apoptotic process ; positive regulation of gene expression ; response to ethanol ; response to xenobiotic stimulus ; skeletal muscle thin filament assembly


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: cytoplasm ; cytosol ; adenylate kinase activity ; AMP binding ; ATP binding ; magnesium ion binding ; nucleoside diphosphate kinase activity ; ADP biosynthetic process ; AMP salvage ; nucleoside diphosphate metabolic process ; nucleoside monophosphate metabolic process ; phosphorylation ; purine ribonucleotide interconversion


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: cytosol ; Golgi apparatus ; nucleoplasm ; nucleus ; transcription regulator complex ; DNA binding ; DNA-binding transcription activator activity, RNA polymerase II-specific ; DNA-binding transcription factor activity, RNA polymerase II-specific ; RNA polymerase II cis-regulatory region sequence-specific DNA binding ; sequence-specific DNA binding ; cell population proliferation ; lens development in camera-type eye ; Leydig cell proliferation ; negative regulation of cell population proliferation ; negative regulation of DNA-templated transcription ; negative regulation of skeletal muscle satellite cell proliferation ; positive regulation of transcription by RNA polymerase II ; regulation of transcription by RNA polymerase II ; spermatid development


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: extracellular region ; extracellular space ; chemorepellent activity ; receptor ligand activity ; semaphorin receptor binding ; branching involved in blood vessel morphogenesis ; gonadotrophin-releasing hormone neuronal migration to the hypothalamus ; negative chemotaxis ; negative regulation of angiogenesis ; negative regulation of axon extension involved in axon guidance ; negative regulation of cell-matrix adhesion ; negative regulation of neuron apoptotic process ; neural crest cell migration ; positive regulation of cell migration ; positive regulation of phosphatidylinositol 3-kinase signaling ; regulation of actin cytoskeleton reorganization ; regulation of cell shape ; semaphorin-plexin signaling pathway ; sprouting angiogenesis ; synapse organization


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: cytoplasm ; nucleus ; protein-containing complex ; protein-DNA complex ; transcription regulator complex ; DNA binding ; DNA-binding transcription activator activity, RNA polymerase II-specific ; DNA-binding transcription factor activity ; DNA-binding transcription factor activity, RNA polymerase II-specific ; RNA polymerase II cis-regulatory region sequence-specific DNA binding ; RNA polymerase II transcription regulatory region sequence-specific DNA binding ; RNA polymerase II-specific DNA-binding transcription factor binding ; sequence-specific DNA binding ; animal organ development ; atrial septum development ; atrial septum morphogenesis ; atrioventricular bundle cell differentiation ; atrioventricular node cell development ; atrioventricular node cell fate commitment ; atrioventricular valve morphogenesis ; bundle of His cell to Purkinje myocyte communication by electrical coupling ; bundle of His development ; cardiac left ventricle formation ; cardiac muscle cell differentiation ; cardiac muscle cell proliferation ; cell fate specification ; cell-cell signaling ; cell-cell signaling involved in cardiac conduction ; embryonic forelimb morphogenesis ; embryonic limb morphogenesis ; endocardial cushion development ; forelimb morphogenesis ; heart development ; lung development ; morphogenesis of an epithelium ; negative regulation of cardiac muscle cell proliferation ; negative regulation of cell migration ; negative regulation of cell population proliferation ; pattern specification process ; pericardium development ; positive regulation of cardiac conduction ; positive regulation of cardiac muscle cell proliferation ; positive regulation of cardioblast differentiation ; positive regulation of DNA-templated transcription ; positive regulation of gap junction assembly ; positive regulation of secondary heart field cardioblast proliferation ; positive regulation of transcription by RNA polymerase II ; regulation of atrial cardiac muscle cell membrane depolarization ; regulation of DNA-templated transcription ; regulation of transcription by RNA polymerase II ; sinoatrial node development ; transcription by RNA polymerase II ; transdifferentiation ; ventricular cardiac muscle tissue development ; ventricular septum development


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: axon ; cell junction ; cell projection ; cortical actin cytoskeleton ; fusome ; lateral plasma membrane ; neuromuscular junction ; plasma membrane ; spectrin ; spectrosome ; actin filament binding ; ankyrin binding ; calmodulin binding ; microtubule binding ; phosphatidylinositol-4,5-bisphosphate binding ; structural constituent of cytoskeleton ; actin cytoskeleton organization ; actin filament capping ; axon guidance ; axon midline choice point recognition ; axonogenesis ; long-term strengthening of neuromuscular junction ; maintenance of presynaptic active zone structure ; negative regulation of microtubule depolymerization ; nervous system development ; neuromuscular synaptic transmission ; neuron development ; photoreceptor cell axon guidance ; regulation of plasma membrane organization ; regulation of synapse organization


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: ATP binding ; G protein-coupled receptor binding ; G protein-coupled receptor kinase activity ; chemotaxis ; G protein-coupled receptor signaling pathway ; hyperosmotic response ; multicellular organismal process ; negative regulation of dopamine receptor signaling pathway ; olfactory behavior ; positive regulation of cation channel activity ; positive regulation of chemotaxis ; positive regulation of growth rate ; positive regulation of locomotion ; positive regulation of oviposition ; protein phosphorylation ; regulation of signal transduction ; response to salt ; serotonin catabolic process


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: nucleus ; site of double-strand break ; ubiquitin ligase complex ; chromatin binding ; histone binding ; K63-linked polyubiquitin modification-dependent protein binding ; metal ion binding ; nucleosome binding ; ubiquitin binding ; ubiquitin-protein transferase activity ; chromatin organization ; DNA damage response ; double-strand break repair ; histone H2A K63-linked ubiquitination ; histone H2A monoubiquitination ; histone H2A-K13 ubiquitination ; histone H2A-K15 ubiquitination ; isotype switching ; negative regulation of transcription elongation by RNA polymerase II ; positive regulation of DNA repair ; protein K63-linked ubiquitination ; protein ubiquitination ; response to ionizing radiation ; ubiquitin-dependent protein catabolic process


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: endosome ; plasma membrane ; ATP binding ; identical protein binding ; protein serine kinase activity ; protein serine/threonine kinase activity ; defense response by callose deposition in cell wall ; defense response to bacterium ; detection of bacterium ; protein phosphorylation ; receptor-mediated endocytosis ; regulation of anion channel activity


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Input: MLVLLAFIIVFHITSAALLLVATIDNAWWVGEEFFADIWKVCVNNTNCTELNDSVQDFSTVQAVQATMILSTILCCIAFLIFLLQLFRLKQGERFVLTSIIQLMACLCVMIAASIYTDRRKDIHEKNEELYAQTSGGSFGYSFILAWVAFAFTFISGLMYLILRKRK

Output: apical part of cell ; apical plasma membrane ; cell surface ; cytoplasm ; cytosol ; Golgi apparatus ; Golgi membrane ; membrane raft ; nucleus ; perinuclear region of cytoplasm ; plasma membrane ; protein kinase binding ; actin filament organization ; actin-mediated cell contraction ; activation of protein kinase activity ; bleb assembly ; blood vessel endothelial cell migration ; cell adhesion ; cell death ; cell migration ; cell-matrix adhesion ; early endosome to late endosome transport ; embryo implantation ; embryonic process involved in female pregnancy ; heart formation ; membrane raft assembly ; natural killer cell proliferation ; neutrophil migration ; plasma membrane raft assembly ; positive regulation of angiogenesis ; positive regulation of cardiac epithelial to mesenchymal transition ; positive regulation of cell population proliferation ; protein localization to cell surface ; protein localization to plasma membrane ; regulation of angiogenesis ; regulation of endothelial cell migration ; regulation of glomerular filtration ; regulation of kinase activity ; regulation of vasculogenesis ; T cell mediated cytotoxicity


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: cytoplasm ; cytoskeleton ; membrane raft ; nucleus ; plasma membrane ; protein-containing complex ; receptor complex ; tumor necrosis factor receptor superfamily complex ; death domain binding ; identical protein binding ; kinase binding ; protein-containing complex binding ; transmembrane receptor protein tyrosine kinase adaptor activity ; tumor necrosis factor receptor binding ; cellular response to tumor necrosis factor ; extrinsic apoptotic signaling pathway ; positive regulation of cell migration ; positive regulation of hair follicle development ; positive regulation of I-kappaB kinase/NF-kappaB signaling ; positive regulation of inflammatory response ; positive regulation of interferon-beta production ; positive regulation of NF-kappaB transcription factor activity ; positive regulation of NIK/NF-kappaB signaling ; tumor necrosis factor-mediated signaling pathway


Instruction: Predict the GO term based on the protein sequence.

Input: MSGTNNVAQARKLVEQLRIEAGIERIKVSKASSDLMGYCEQHARNDPLLVGVPASENPFKDKKPCIIL

Output: heterotrimeric G-protein complex ; G-protein beta-subunit binding ; behavioral fear response ; G protein-coupled receptor signaling pathway ; locomotory behavior ; receptor guanylyl cyclase signaling pathway ; regulation of adenylate cyclase activity


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: basolateral plasma membrane ; cell surface ; cytoplasm ; external side of plasma membrane ; extracellular space ; plasma membrane ; collagen binding ; integrin binding ; laminin binding ; metal ion binding ; metalloendopeptidase activity ; metalloendopeptidase activity involved in amyloid precursor protein catabolic process ; metallopeptidase activity ; protein kinase C binding ; SH3 domain binding ; amyloid precursor protein catabolic process ; cell adhesion ; cell adhesion mediated by integrin ; cell migration ; cell-cell adhesion mediated by integrin ; cell-matrix adhesion ; cellular response to lipopolysaccharide ; membrane protein ectodomain proteolysis ; membrane protein intracellular domain proteolysis ; monocyte activation ; positive regulation of cell adhesion mediated by integrin ; positive regulation of cell migration ; positive regulation of keratinocyte migration ; positive regulation of macrophage fusion ; positive regulation of MAP kinase activity ; positive regulation of membrane protein ectodomain proteolysis ; positive regulation of protein secretion ; protein processing ; response to calcium ion ; response to glucocorticoid ; response to hydrogen peroxide ; response to manganese ion ; response to tumor necrosis factor ; transforming growth factor beta receptor signaling pathway


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: apical plasma membrane ; basolateral plasma membrane ; cation-transporting ATPase complex ; cell surface ; cytoplasm ; endoplasmic reticulum ; endoplasmic reticulum membrane ; intercalated disc ; membrane ; membrane raft ; mitochondrion ; nucleoplasm ; perinuclear region of cytoplasm ; plasma membrane ; sarcolemma ; T-tubule ; transporter complex ; calcium-dependent protein binding ; calmodulin binding ; ion binding ; potassium:proton antiporter activity ; protein phosphatase 2B binding ; sodium:proton antiporter activity ; cardiac muscle cell contraction ; cardiac muscle cell differentiation ; cellular response to acidic pH ; cellular response to antibiotic ; cellular response to cold ; cellular response to electrical stimulus ; cellular response to epinephrine stimulus ; cellular response to hypoxia ; cellular response to insulin stimulus ; hyaluronan catabolic process ; intracellular sodium ion homeostasis ; negative regulation of apoptotic process ; neuron death ; positive regulation of action potential ; positive regulation of apoptotic process ; positive regulation of calcineurin-NFAT signaling cascade ; positive regulation of calcium:sodium antiporter activity ; positive regulation of cardiac muscle hypertrophy ; positive regulation of cell growth ; positive regulation of intracellular signal transduction ; positive regulation of mitochondrial membrane permeability ; positive regulation of the force of heart contraction ; positive regulation of transcription by RNA polymerase II ; potassium ion transmembrane transport ; protein complex oligomerization ; proton transmembrane transport ; regulation of cardiac muscle contraction by calcium ion signaling ; regulation of intracellular pH ; regulation of pH ; regulation of sensory perception of pain ; regulation of the force of heart contraction ; regulation of the force of heart contraction by cardiac conduction ; response to acidic pH ; response to muscle stretch ; response to organic cyclic compound ; sodium ion export across plasma membrane ; sodium ion import across plasma membrane ; sodium ion transport ; stem cell differentiation


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: mitochondrion ; peroxisomal membrane ; peroxisome ; ABC-type transporter activity ; acyl-CoA hydrolase activity ; ATP binding ; ATP hydrolysis activity ; ATPase-coupled transmembrane transporter activity ; long-chain fatty acid transporter activity ; protein heterodimerization activity ; protein homodimerization activity ; fatty acid beta-oxidation ; long-chain fatty acid import into peroxisome ; myelin maintenance ; negative regulation of cytokine production involved in inflammatory response ; negative regulation of reactive oxygen species biosynthetic process ; neuron projection maintenance ; peroxisome organization ; positive regulation of fatty acid beta-oxidation ; positive regulation of unsaturated fatty acid biosynthetic process ; response to bacterium ; very long-chain fatty acid catabolic process ; very long-chain fatty acid metabolic process


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: cytoplasm ; extracellular region ; glutamatergic synapse ; plasma membrane ; protein-containing complex ; synapse ; coreceptor activity ; interleukin-1 receptor activity ; interleukin-1 receptor binding ; interleukin-33 receptor activity ; NAD(P)+ nucleosidase activity ; NAD+ nucleotidase, cyclic ADP-ribose generating ; cytokine-mediated signaling pathway ; inflammatory response ; innate immune response ; interleukin-1-mediated signaling pathway ; interleukin-33-mediated signaling pathway ; positive regulation of interleukin-13 production ; positive regulation of interleukin-4 production ; positive regulation of interleukin-5 production ; positive regulation of interleukin-6 production ; positive regulation of NF-kappaB transcription factor activity ; positive regulation of synapse assembly ; regulation of postsynaptic density assembly ; regulation of presynapse assembly ; synaptic membrane adhesion ; trans-synaptic signaling by trans-synaptic complex


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Output: acrosomal vesicle ; centriolar satellite ; centriole ; centrosome ; ciliary basal body ; ciliary transition zone ; intercellular bridge ; intracellular membrane-bounded organelle ; manchette ; microtubule cytoskeleton ; nuclear membrane ; nucleoplasm ; sperm head-tail coupling apparatus ; protein homodimerization activity ; protein-containing complex binding ; cell cycle ; cilium assembly ; intraciliary transport ; intraciliary transport involved in cilium assembly ; intramanchette transport ; manchette assembly ; non-motile cilium assembly ; positive regulation of cell population proliferation ; positive regulation of intracellular protein transport ; protein localization to centrosome ; regulation of centrosome duplication ; sperm axoneme assembly ; spermatid development ; spermatogenesis


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: catalytic complex ; endoplasmic reticulum ; rough endoplasmic reticulum membrane ; ferrous iron binding ; L-ascorbic acid binding ; peptide binding ; procollagen-lysine 5-dioxygenase activity ; cellular response to hormone stimulus ; epidermis development ; peptidyl-lysine hydroxylation ; response to hypoxia


Instruction: Predict the GO term based on the protein sequence.

Output: endoplasmic reticulum membrane ; Golgi membrane ; plasma membrane ; monoatomic cation transmembrane transporter activity ; sodium ion transmembrane transporter activity ; potassium ion transport ; sodium ion transmembrane transport


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: nucleus ; DNA binding ; DNA-binding transcription factor activity ; auxin mediated signaling pathway involved in phyllotactic patterning ; callus formation ; ethylene-activated signaling pathway ; lateral root formation ; leaf phyllotactic patterning ; maintenance of shoot apical meristem identity ; phyllotactic patterning


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: nuclear telomere cap complex ; G-rich strand telomeric DNA binding ; RNA binding ; single-stranded telomeric DNA binding ; telomerase inhibitor activity ; negative regulation of telomerase activity ; regulation of telomere maintenance via telomerase ; telomere capping ; telomere maintenance


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: endoplasmic reticulum membrane ; Golgi membrane ; nuclear envelope ; organelle membrane ; plasma membrane ; G protein-coupled receptor activity ; response to N-phenylthiourea ; slug development involved in sorocarp development ; sorocarp development ; sporulation resulting in formation of a cellular spore


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: cytoplasm ; Ino80 complex ; NuA4 histone acetyltransferase complex ; nucleolus ; nucleus ; SWI/SNF complex ; Swr1 complex ; chromatin binding ; structural constituent of cytoskeleton ; chromatin organization ; histone H4 acetylation ; long-day photoperiodism, flowering ; pollen sperm cell differentiation ; regulation of transcription by RNA polymerase II


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: anaphase-promoting complex ; nucleus ; ubiquitin protein ligase binding ; cell differentiation ; cell division ; metaphase/anaphase transition of mitotic cell cycle ; negative regulation of gene expression ; nervous system development ; positive regulation of axon extension ; positive regulation of dendrite morphogenesis ; positive regulation of synapse maturation ; positive regulation of synaptic plasticity ; protein K11-linked ubiquitination ; ubiquitin-dependent protein catabolic process


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: cytoplasm ; external side of plasma membrane ; plasma membrane ; calcium ion binding ; cargo receptor activity ; hyaluronic acid binding ; low-density lipoprotein particle binding ; low-density lipoprotein particle receptor activity ; scavenger receptor activity ; cell adhesion ; defense response to bacterium ; defense response to Gram-positive bacterium ; endocytosis ; hyaluronan catabolic process ; receptor-mediated endocytosis


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Input: MNLEEKPTMTASRASPQAEHLYYVRCSICNTILAVGIPLKRMLDTVTVKCGHCGNLSFLTTTPPLQGHVSLTLQMQSFGGSDYKKGSSSSSSSSTSSDQPPSPSPPFVVKPPEKKQRLPSAYNRFMRDEIQRIKSANPEIPHREAFSAAAKNWAKYIPNSPTSITSGGHNMIHGLGFGEKK

Output: nucleus ; DNA-binding transcription factor activity ; metal ion binding ; sequence-specific DNA binding ; transcription cis-regulatory region binding ; carpel development ; cell fate commitment ; floral meristem determinacy ; leaf development ; nectary development ; polarity specification of adaxial/abaxial axis ; regulation of DNA-templated transcription ; style development


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: cytosol ; extrinsic component of membrane ; nucleus ; phagophore assembly site membrane ; vacuolar membrane ; phosphatidylinositol-3,5-bisphosphate binding ; phosphatidylinositol-3-phosphate binding ; autophagy ; autophagy of mitochondrion ; autophagy of nucleus ; defense response to fungus ; leaf senescence ; positive regulation of autophagy ; protein lipidation ; protein localization to phagophore assembly site ; protein transport ; response to osmotic stress ; response to oxidative stress ; response to salt stress ; response to starvation ; response to water deprivation


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: nucleus ; DNA binding ; DNA-binding transcription factor activity ; metal ion binding ; transcription cis-regulatory region binding ; flower development ; regulation of DNA-templated transcription


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: ciliary membrane ; plasma membrane ; receptor complex ; G protein-coupled peptide receptor activity ; G protein-coupled receptor activity ; peptide binding ; prosaposin receptor activity ; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway ; Bergmann glial cell differentiation ; negative regulation of astrocyte differentiation ; negative regulation of hydrogen peroxide-induced cell death ; negative regulation of neuron differentiation ; negative regulation of smoothened signaling pathway ; negative regulation of systemic arterial blood pressure ; positive regulation of cerebellar granule cell precursor proliferation ; positive regulation of MAPK cascade ; smoothened signaling pathway


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Input: MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSCQLL

Output: cell-cell junction ; cytosol ; glutamatergic synapse ; lipid droplet ; plasma membrane ; G protein activity ; GDP binding ; GTP binding ; GTPase activity ; protein-containing complex binding ; calcium-ion regulated exocytosis ; cell population proliferation ; cellular response to cAMP ; cellular response to organic cyclic compound ; cellular response to xenobiotic stimulus ; establishment of endothelial barrier ; establishment of localization in cell ; modification of postsynaptic structure ; negative regulation of calcium ion-dependent exocytosis ; negative regulation of synaptic vesicle exocytosis ; positive regulation of ERK1 and ERK2 cascade ; positive regulation of integrin activation ; Rap protein signal transduction ; regulation of cell junction assembly ; regulation of establishment of cell polarity ; small GTPase mediated signal transduction


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Output: cytosol ; thiaminase activity ; thiamine biosynthetic process ; thiamine diphosphate biosynthetic process


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: cell plate ; nuclear envelope ; nuclear membrane ; protein heterodimerization activity ; protein homodimerization activity ; nucleus organization


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: mitochondrion ; endonuclease activity ; Group II intron splicing ; intron homing ; mitochondrial mRNA processing ; mitochondrion organization


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: nucleus ; DNA-binding transcription factor activity ; DNA-binding transcription factor activity, RNA polymerase II-specific ; lipid binding ; transcription cis-regulatory region binding ; cell differentiation ; plant-type cell wall loosening ; trichome branching


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: chloroplast ; chloroplast nucleoid ; chromosome, telomeric region ; DNA repair complex ; extracellular region ; DNA binding ; mRNA binding ; single-stranded DNA binding ; telomeric DNA binding ; defense response ; DNA repair ; negative regulation of telomere maintenance via telomerase ; regulation of DNA-templated transcription ; regulation of telomere maintenance ; salicylic acid mediated signaling pathway ; systemic acquired resistance


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: plasma membrane ; vacuole ; N-acylphosphatidylethanolamine-specific phospholipase D activity ; phospholipase D activity ; cellular response to nitrogen starvation ; cellular response to phosphate starvation ; galactolipid biosynthetic process ; inositol lipid-mediated signaling ; lipid biosynthetic process ; phosphatidic acid biosynthetic process ; phospholipid catabolic process ; regulation of vesicle-mediated transport ; response to auxin ; root development


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: nucleus ; DNA-binding transcription factor activity ; sequence-specific DNA binding ; transcription cis-regulatory region binding ; positive regulation of DNA-templated transcription ; positive regulation of wax biosynthetic process ; regulation of DNA-templated transcription ; response to auxin ; response to water deprivation


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: nucleus ; cis-regulatory region sequence-specific DNA binding ; DNA-binding transcription factor activity ; zinc ion binding ; cellularization ; egg activation ; female meiotic nuclear division ; homologous chromosome segregation ; pole cell formation ; positive regulation of transcription by RNA polymerase II ; regulation of transcription by RNA polymerase II


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: ATAC complex ; MLL1/2 complex ; MLL3/4 complex ; NSL complex ; nucleus ; Set1C/COMPASS complex ; histone binding ; chromatin remodeling ; eye development ; haltere development ; heart development ; histone H3-K4 methylation ; positive regulation of proteasomal ubiquitin-dependent protein catabolic process


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: plasma membrane ; receptor complex ; ATP binding ; protein tyrosine kinase activity ; transmembrane receptor protein tyrosine kinase activity ; Wnt-protein binding ; muscle cell cellular homeostasis ; photoreceptor cell axon guidance ; positive regulation of kinase activity ; positive regulation of neuron projection development ; positive regulation of phosphatidylinositol 3-kinase signaling ; protein phosphorylation ; rhabdomere development ; signal transduction ; transmembrane receptor protein tyrosine kinase signaling pathway


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Input: MAASGEQAPCSVYFCGSIRGGREDQALYARIVSRLRRYGKVLTEHVADAELEPLGEEAAGGDQFIHEQDLNWLQQADVVVAEVTQPSLGVGYELGRAVALGKPILCLFRPQSGRVLSAMIRGAADGSRFQVWDYAEGEVETMLDRYFEAYLPQKTASSSHPSA

Output: cytoplasm ; nucleus ; deoxyribonucleoside 5'-monophosphate N-glycosidase activity ; identical protein binding ; protein homodimerization activity ; allantoin metabolic process ; deoxyribonucleoside monophosphate catabolic process ; dGMP catabolic process ; epithelial cell differentiation ; nucleoside metabolic process ; positive regulation of cell growth


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: BRCA2-MAGE-D1 complex ; centrosome ; chromosome ; chromosome, telomeric region ; cytoplasm ; DNA repair complex ; lateral element ; nuclear ubiquitin ligase complex ; nucleus ; protein-containing complex ; secretory granule ; gamma-tubulin binding ; histone H3 acetyltransferase activity ; histone H4 acetyltransferase activity ; identical protein binding ; protease binding ; single-stranded DNA binding ; brain development ; cell population proliferation ; cellular response to ionizing radiation ; cellular senescence ; centrosome duplication ; chordate embryonic development ; chromosome organization ; DNA damage response ; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator ; DNA recombination ; double-strand break repair ; double-strand break repair via homologous recombination ; establishment of protein localization to telomere ; female gonad development ; hematopoietic stem cell proliferation ; hemopoiesis ; histone H3 acetylation ; histone H4 acetylation ; homologous chromosome orientation involved in meiotic metaphase I plate congression ; inner cell mass cell proliferation ; intrinsic apoptotic signaling pathway in response to DNA damage ; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ; male meiosis I ; mammary gland development ; mitotic recombination-dependent replication fork processing ; multicellular organism growth ; negative regulation of mammary gland epithelial cell proliferation ; nucleotide-excision repair ; oocyte maturation ; positive regulation of DNA-templated transcription ; positive regulation of mitotic cell cycle ; regulation of cytokinesis ; regulation of DNA-templated transcription ; replication fork processing ; response to estradiol ; response to gamma radiation ; response to nutrient ; response to UV-C ; response to X-ray ; spermatogenesis ; stem cell proliferation ; telomere maintenance via recombination


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: endoplasmic reticulum ; extracellular region ; nucleus ; DNA binding ; DNA endonuclease activity ; endonuclease activity ; apoptotic DNA fragmentation ; DNA catabolic process ; DNA catabolic process, endonucleolytic ; neutrophil activation involved in immune response ; programmed cell death involved in cell development ; regulation of acute inflammatory response ; regulation of neutrophil mediated cytotoxicity


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: cytoplasm ; cytoplasmic vesicle ; endosome membrane ; late endosome ; late endosome membrane ; lysosomal membrane ; plasma membrane ; antiporter activity ; metal ion binding ; zinc ion transmembrane transporter activity ; lactation ; regulation of sequestering of zinc ion ; response to toxic substance ; response to vitamin A ; response to zinc ion ; zinc export across plasma membrane ; zinc ion transmembrane transport ; zinc ion transport


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: cytoplasm ; nucleus ; phosphorelay response regulator activity ; protein serine/threonine kinase activity ; circadian rhythm ; cytokinin-activated signaling pathway ; embryo development ending in seed dormancy ; protein autophosphorylation ; red or far-red light signaling pathway ; regulation of DNA-templated transcription ; response to cytokinin ; response to red light


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: AMPA glutamate receptor complex ; cell surface ; cerebellar mossy fiber ; cytosol ; glutamatergic synapse ; hippocampal mossy fiber to CA3 synapse ; plasma membrane ; postsynaptic density ; postsynaptic density membrane ; Schaffer collateral - CA1 synapse ; somatodendritic compartment ; voltage-gated calcium channel complex ; channel regulator activity ; ionotropic glutamate receptor binding ; voltage-gated calcium channel activity ; eye blink reflex ; membrane depolarization ; membrane hyperpolarization ; nervous system process ; neuromuscular junction development ; neurotransmitter receptor internalization ; neurotransmitter receptor localization to postsynaptic specialization membrane ; neurotransmitter receptor transport, postsynaptic endosome to lysosome ; positive regulation of AMPA receptor activity ; positive regulation of protein localization to basolateral plasma membrane ; positive regulation of synaptic transmission, glutamatergic ; postsynaptic neurotransmitter receptor diffusion trapping ; protein targeting to membrane ; regulation of AMPA receptor activity ; regulation of membrane potential ; regulation of postsynaptic membrane neurotransmitter receptor levels ; regulation of postsynaptic neurotransmitter receptor activity ; response to calcium ion ; transmission of nerve impulse


Instruction: For a given protein sequence, identify the appropriate Gene Ontology term that corresponds to its molecular function, biological process, and cellular component.

Input: MKLLAMVALLVTICSLEGALVKRQADGPDMQSLFTQYFQSMTDYGKDLMEKAKTSEIQSQAKAYFEKTHEQLTPLVRSAGTSLVNFFSSLMNLEEKPAPAAK

Output: chylomicron ; cytosol ; extracellular region ; extracellular space ; high-density lipoprotein particle ; spherical high-density lipoprotein particle ; very-low-density lipoprotein particle ; apolipoprotein receptor binding ; cholesterol binding ; cholesterol transfer activity ; enzyme binding ; heat shock protein binding ; high-density lipoprotein particle binding ; high-density lipoprotein particle receptor binding ; lipase inhibitor activity ; lipid binding ; lipid transporter activity ; phosphatidylcholine binding ; phosphatidylcholine-sterol O-acyltransferase activator activity ; phospholipid binding ; protein heterodimerization activity ; protein homodimerization activity ; signaling receptor binding ; animal organ regeneration ; cholesterol efflux ; cholesterol homeostasis ; cholesterol metabolic process ; cholesterol transport ; diacylglycerol catabolic process ; high-density lipoprotein particle assembly ; high-density lipoprotein particle clearance ; high-density lipoprotein particle remodeling ; lipid transport ; lipoprotein metabolic process ; low-density lipoprotein particle remodeling ; negative regulation of cholesterol import ; negative regulation of cholesterol transport ; negative regulation of cholesterol transporter activity ; negative regulation of cytokine production involved in immune response ; negative regulation of lipase activity ; negative regulation of lipid catabolic process ; negative regulation of very-low-density lipoprotein particle remodeling ; peptidyl-methionine modification ; phosphatidylcholine biosynthetic process ; phospholipid catabolic process ; phospholipid efflux ; positive regulation of CoA-transferase activity ; positive regulation of interleukin-8 production ; positive regulation of lipid catabolic process ; positive regulation of phagocytosis ; protein oxidation ; protein stabilization ; regulation of intestinal cholesterol absorption ; regulation of protein stability ; response to glucose ; reverse cholesterol transport ; triglyceride-rich lipoprotein particle remodeling


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: dendrite ; nucleolus ; nucleoplasm ; nucleus ; DNA binding ; RNA binding ; anatomical structure development ; brain development ; extracellular matrix organization ; learning ; lung alveolus development ; memory ; negative regulation of transcription by RNA polymerase II ; positive regulation of hematopoietic stem cell proliferation ; regulation of DNA-templated transcription ; social behavior ; transcription by RNA polymerase II


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: cytosolic small ribosomal subunit ; extrinsic component of mitochondrial outer membrane ; neuron projection ; neuronal cell body ; nucleus ; protein tag ; structural constituent of ribosome ; ubiquitin protein ligase binding ; energy homeostasis ; fat pad development ; female gonad development ; female meiosis I ; hypothalamus gonadotrophin-releasing hormone neuron development ; male meiosis I ; mitochondrion transport along microtubule ; modification-dependent protein catabolic process ; neuron projection morphogenesis ; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator ; positive regulation of protein monoubiquitination ; protein ubiquitination ; regulation of mitochondrial membrane potential ; regulation of neuron death ; regulation of proteasomal protein catabolic process ; seminiferous tubule development


Instruction: Predict the GO term based on the protein sequence.

Output: cytosol ; Golgi-associated vesicle ; late endosome ; trans-Golgi network ; guanyl-nucleotide exchange factor activity ; autophagosome assembly ; endoplasmic reticulum to Golgi vesicle-mediated transport ; intra-Golgi vesicle-mediated transport ; protein transport ; regulation of ARF protein signal transduction


Instruction: Predict the GO term based on the protein sequence.

Output: axon ; axon terminus ; cell cortex ; cytoplasm ; GABA-ergic synapse ; inhibitory synapse ; neuron projection terminus ; presynapse ; presynaptic active zone ; synapse ; glutamate binding ; glutamate decarboxylase activity ; identical protein binding ; protein-containing complex binding ; pyridoxal phosphate binding ; gamma-aminobutyric acid biosynthetic process ; glutamate catabolic process ; locomotory exploration behavior ; neurotransmitter biosynthetic process ; protein-pyridoxal-5-phosphate linkage ; response to xenobiotic stimulus ; social behavior


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: axon terminus ; cytoplasm ; dopaminergic synapse ; GABA-ergic synapse ; glutamatergic synapse ; neuronal cell body ; plasma membrane ; postsynaptic density membrane ; postsynaptic membrane ; presynapse ; presynaptic active zone membrane ; receptor complex ; synapse ; adenylate cyclase inhibitor activity ; adrenergic receptor activity ; alpha-2C adrenergic receptor binding ; alpha2-adrenergic receptor activity ; enzyme regulator activity ; epinephrine binding ; heterotrimeric G-protein binding ; molecular function activator activity ; norepinephrine binding ; potassium channel activator activity ; protein heterodimerization activity ; protein homodimerization activity ; protein kinase binding ; thioesterase binding ; activation of protein kinase activity ; activation of protein kinase B activity ; acute inflammatory response ; adenylate cyclase-activating adrenergic receptor signaling pathway ; adenylate cyclase-inhibiting adrenergic receptor signaling pathway ; adrenergic receptor signaling pathway ; cellular response to hormone stimulus ; DNA replication ; fear response ; female pregnancy ; G protein-coupled receptor signaling pathway ; glucose homeostasis ; negative regulation of calcium ion-dependent exocytosis ; negative regulation of insulin secretion ; negative regulation of insulin secretion involved in cellular response to glucose stimulus ; negative regulation of lipid catabolic process ; negative regulation of uterine smooth muscle contraction ; phospholipase C-activating adrenergic receptor signaling pathway ; platelet activation ; positive regulation of cell migration ; positive regulation of cytokine production ; positive regulation of epidermal growth factor-activated receptor activity ; positive regulation of MAP kinase activity ; positive regulation of MAPK cascade ; positive regulation of membrane protein ectodomain proteolysis ; positive regulation of wound healing ; presynaptic modulation of chemical synaptic transmission ; receptor transactivation ; regulation of synaptic vesicle exocytosis ; regulation of vasoconstriction ; signal transduction ; thermoception ; vasodilation


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: cytoplasm ; mitochondrion ; glycogen (starch) synthase activity ; glycogen biosynthetic process


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: cell periphery ; extracellular region ; fungal-type cell wall ; mating projection ; membrane ; cell adhesion ; cell morphogenesis involved in conjugation with cellular fusion ; cell wall organization ; cytogamy ; filamentous growth of a population of unicellular organisms ; invasive growth in response to glucose limitation ; regulation of cell shape ; response to pheromone


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Input: MGKKTFREWQYFKLSITSFDQDVDDAHAIDQMTWRQWLNNALKRSYGIFGEGVEYSFLHVDDKLAYIRVNHADKDTFSSSISTYISTDELVGSPLTVSILQESSSLRLLEVTDDDRLWLKKVMEEEEQDCKCI

Output: cytosol ; nucleolar ribonuclease P complex ; nucleus ; ribonuclease MRP complex ; ribonuclease P activity ; intronic box C/D RNA processing ; maturation of 5.8S rRNA ; mRNA cleavage ; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay ; tRNA 5'-leader removal ; tRNA processing


Instruction: Predict the GO term based on the protein sequence.

Output: fungal-type vacuole ; nuclear envelope ; nucleus ; metal ion binding ; metalloendopeptidase activity ; metallopeptidase activity ; SUMO binding ; SUMO ligase activity ; DNA repair ; histone catabolic process ; protein autosumoylation ; protein sumoylation ; protein-DNA covalent cross-linking repair ; proteolysis ; replication-born double-strand break repair via sister chromatid exchange ; translesion synthesis


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: acetoin dehydrogenase activity ; acetyl-CoA synthetase acetyltransferase activity ; acetoin catabolic process ; butanediol catabolic process ; carbon catabolite repression of transcription by glucose ; cellular response to acetate ; spore germination ; sporulation resulting in formation of a cellular spore


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: cytoplasm ; IMP dehydrogenase activity ; metal ion binding ; mRNA binding ; nucleotide binding ; GMP biosynthetic process ; GTP biosynthetic process


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: cytoplasm ; nucleolus ; small-subunit processome ; ATPase activator activity ; RNA binding ; endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; maturation of SSU-rRNA ; small-subunit processome assembly


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: NuA4 histone acetyltransferase complex ; nuclear speck ; nucleosome ; Sin3 complex ; chromatin binding ; cell population proliferation ; chromatin remodeling ; double-strand break repair via homologous recombination ; fibroblast proliferation ; histone acetylation ; histone deacetylation ; histone H2A acetylation ; histone H4 acetylation ; positive regulation of DNA-templated transcription ; positive regulation of double-strand break repair via homologous recombination ; regulation of apoptotic process ; regulation of cell cycle ; regulation of double-strand break repair


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: cytoplasm ; cytosol ; cytosolic large ribosomal subunit ; cytosolic ribosome ; polysomal ribosome ; postsynapse ; postsynaptic density ; presynapse ; ribosome ; synapse ; 5.8S rRNA binding ; RNA binding ; structural constituent of ribosome ; cellular response to nerve growth factor stimulus ; cytoplasmic translation ; translation at postsynapse ; translation at presynapse


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: membrane ; plasma membrane ; potassium ion transmembrane transporter activity ; potassium:proton symporter activity ; cellular response to cesium ion ; potassium ion transmembrane transport ; potassium ion transport


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: cell body ; cytoplasm ; cytoplasmic ribonucleoprotein granule ; intercellular bridge ; membrane raft ; microtubule ; mitotic spindle ; nuclear envelope lumen ; nucleus ; protein-containing complex ; GTP binding ; GTPase activating protein binding ; GTPase activity ; metal ion binding ; MHC class I protein binding ; protein domain specific binding ; protein-containing complex binding ; structural constituent of cytoskeleton ; ubiquitin protein ligase binding ; microtubule cytoskeleton organization ; microtubule-based process ; mitotic cell cycle ; odontoblast differentiation ; regulation of synapse organization ; spindle assembly


Instruction: Determine the Gene Ontology term that best describes the attributes of a given protein sequence.

Output: acrosomal vesicle ; membrane ; mitochondrial membrane ; mitochondrial nucleoid ; mitochondrial outer membrane ; mitochondrion ; pore complex ; sperm midpiece ; synaptic vesicle ; ceramide binding ; cholesterol binding ; nucleotide binding ; phosphatidylcholine binding ; porin activity ; voltage-gated monoatomic anion channel activity ; binding of sperm to zona pellucida ; mitochondrial outer membrane permeabilization ; monoatomic anion transport ; negative regulation of intrinsic apoptotic signaling pathway ; negative regulation of protein polymerization


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: chromatin ; cytoplasm ; nucleus ; pseudopodium ; metal ion binding ; myosin phosphatase activity ; protein serine/threonine phosphatase activity ; amoeboid sperm motility ; cell differentiation ; male meiosis chromosome segregation ; oviposition ; regulation of pseudopodium assembly ; reproduction ; spermatogenesis


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Input: MPPKGWRKDAQGNYPTTSYIKEQENITIQDLLFPKSTIVNLAREVPQQSGKKLLINKDASLALQRGATVFVNHLLLFAREIAKSQDKKSCSVDDVLSALDHIGHSALKGPVRDKLDEYQAAVEQRKKEKLDSGEVDADGDIDMGEDKENVPVEKVKEHDEIEEQGDALQDVEESSEKKQKTESQDVETRVQNLEQT

Output: CHRAC ; epsilon DNA polymerase complex ; nuclear replication fork ; nucleus ; chromatin DNA binding ; nucleosomal DNA binding ; protein heterodimerization activity ; chromatin remodeling ; DNA damage response ; DNA-templated DNA replication ; error-prone translesion synthesis ; heterochromatin formation ; leading strand elongation ; regulation of DNA-templated transcription


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: plasma membrane ; ATP binding ; calcium ion binding ; polysaccharide binding ; protein serine kinase activity ; protein serine/threonine kinase activity ; cell surface receptor signaling pathway ; protein phosphorylation


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: cytoplasm ; intracellular cyclic nucleotide activated cation channel complex ; photoreceptor outer segment ; photoreceptor outer segment membrane ; plasma membrane ; protein-containing complex ; cAMP binding ; cGMP binding ; identical protein binding ; intracellular cAMP-activated cation channel activity ; intracellular cGMP-activated cation channel activity ; molecular adaptor activity ; molecular sequestering activity ; protein homodimerization activity ; protein-containing complex binding ; monoatomic cation transmembrane transport ; positive regulation of gene expression ; response to stimulus ; retina homeostasis ; sensory perception of smell ; visual perception


Instruction: Given a protein sequence, predict the Gene Ontology term that describes its attributes in terms of molecular function, biological process, and cellular component.

Output: membrane ; plasma membrane ; G protein-coupled receptor activity ; lipid binding ; molecular function activator activity ; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway ; cellular response to fatty acid ; G protein-coupled receptor signaling pathway ; glucose homeostasis ; inflammatory response ; mucosal immune response ; negative regulation of blood pressure ; negative regulation of insulin secretion ; neuronal action potential ; positive regulation of acute inflammatory response to non-antigenic stimulus ; positive regulation of chemokine production ; positive regulation of cytokine production involved in immune response ; positive regulation of neuronal action potential ; regulation of heart rate by chemical signal ; regulation of hormone biosynthetic process ; regulation of insulin receptor signaling pathway ; regulation of norepinephrine secretion ; regulation of peptide hormone secretion


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: membrane ; plasma membrane ; synapse ; ATP binding ; potassium:chloride symporter activity ; protein kinase binding ; cell volume homeostasis ; chemical synaptic transmission ; chloride ion homeostasis ; chloride transmembrane transport ; potassium ion homeostasis ; potassium ion import across plasma membrane ; potassium ion transmembrane transport


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: cytoplasm ; cytosol ; ATP binding ; identical protein binding ; magnesium ion binding ; protein kinase binding ; protein serine kinase activity ; protein serine/threonine kinase activity ; cellular hypotonic response ; cellular response to chemokine ; chemokine (C-C motif) ligand 21 signaling pathway ; chemokine (C-X-C motif) ligand 12 signaling pathway ; intracellular signal transduction ; negative regulation of potassium ion transmembrane transport ; negative regulation of potassium ion transmembrane transporter activity ; osmosensory signaling pathway ; peptidyl-threonine phosphorylation ; positive regulation of T cell chemotaxis ; protein autophosphorylation ; protein phosphorylation ; response to oxidative stress ; response to xenobiotic stimulus ; signal transduction


Instruction: Provide the Gene Ontology term that matches the characteristics of a given protein sequence.

Output: apical plasma membrane ; cell surface ; cytoplasm ; early endosome membrane ; glial cell projection ; Golgi membrane ; intracellular membrane-bounded organelle ; membrane ; phagocytic cup ; plasma membrane ; ruffle membrane ; ABC-type transporter activity ; apolipoprotein A-I receptor activity ; ATP binding ; ATP hydrolysis activity ; ATPase-coupled transmembrane transporter activity ; floppase activity ; phosphatidylcholine floppase activity ; phosphatidylserine floppase activity ; phospholipid transporter activity ; amyloid-beta clearance by cellular catabolic process ; amyloid-beta formation ; apolipoprotein A-I-mediated signaling pathway ; cholesterol efflux ; high-density lipoprotein particle assembly ; memory ; negative regulation of amyloid precursor protein biosynthetic process ; negative regulation of amyloid-beta formation ; negative regulation of endocytosis ; negative regulation of MAPK cascade ; negative regulation of PERK-mediated unfolded protein response ; peptide cross-linking ; phagocytosis ; phospholipid efflux ; phospholipid translocation ; phospholipid transport ; plasma membrane raft organization ; positive regulation of amyloid-beta clearance ; positive regulation of cholesterol efflux ; positive regulation of engulfment of apoptotic cell ; positive regulation of ERK1 and ERK2 cascade ; positive regulation of phagocytosis ; positive regulation of phospholipid efflux ; positive regulation of protein localization to cell surface ; protein localization to nucleus ; regulation of amyloid precursor protein catabolic process ; regulation of lipid metabolic process ; visual learning


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: CA3 pyramidal cell dendrite ; cell surface ; collagen-containing extracellular matrix ; extracellular matrix ; extracellular space ; hippocampal mossy fiber expansion ; neuron projection ; neuronal cell body ; tenascin complex ; identical protein binding ; integrin binding ; axonogenesis ; cell-matrix adhesion ; dendrite self-avoidance ; negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation ; negative regulation of neuron migration ; negative regulation of osteoblast differentiation ; negative regulation of osteoblast proliferation ; neuron migration ; neuron projection extension ; osteoblast development ; positive regulation of neuron projection development ; positive regulation of sprouting angiogenesis ; regulation of bone development ; regulation of cell adhesion ; regulation of cell migration ; regulation of smooth muscle tissue development


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: nucleus ; regulation of defense response ; regulation of jasmonic acid mediated signaling pathway ; response to wounding


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: external side of plasma membrane ; plasma membrane ; identical protein binding ; adaptive immune response ; innate immune response ; regulation of natural killer cell activation ; T cell activation


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: endoplasmic reticulum ; endoplasmic reticulum membrane ; Golgi apparatus ; Golgi membrane ; GTP binding ; palmitoyltransferase activity ; N-terminal peptidyl-L-cysteine N-palmitoylation ; protein palmitoylation ; smoothened signaling pathway


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: cytoplasm ; cytosol ; endoplasmic reticulum ; membrane ; neuron projection ; nucleus ; perinuclear region of cytoplasm ; plasma membrane ; ruffle ; ruffle membrane ; trans-Golgi network ; inositol bisphosphate phosphatase activity ; inositol trisphosphate phosphatase activity ; inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity ; inositol-1,4,5-trisphosphate 5-phosphatase activity ; inositol-polyphosphate 5-phosphatase activity ; phosphatidylinositol phosphate 5-phosphatase activity ; phosphatidylinositol trisphosphate phosphatase activity ; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity ; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity ; vasopressin receptor activity ; cellular response to cAMP ; cellular response to epidermal growth factor stimulus ; cellular response to hormone stimulus ; cellular response to insulin stimulus ; cellular response to tumor necrosis factor ; dephosphorylation ; G protein-coupled receptor signaling pathway ; glucose homeostasis ; in utero embryonic development ; negative regulation by host of viral transcription ; negative regulation of calcium ion transport ; negative regulation of dephosphorylation ; negative regulation of DNA-templated transcription ; negative regulation of glucose transmembrane transport ; negative regulation of glycogen (starch) synthase activity ; negative regulation of glycogen biosynthetic process ; negative regulation of insulin receptor signaling pathway ; negative regulation of MAP kinase activity ; negative regulation of peptidyl-serine phosphorylation ; negative regulation of peptidyl-threonine phosphorylation ; negative regulation of protein kinase activity ; negative regulation of protein kinase B signaling ; negative regulation of protein phosphorylation ; negative regulation of protein targeting to membrane ; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate ; negative regulation of stress fiber assembly ; phosphatidylinositol dephosphorylation ; positive regulation of DNA-templated transcription ; positive regulation of renal water transport ; positive regulation of urine volume ; protein localization to plasma membrane ; regulation of glycogen biosynthetic process ; response to insulin ; ruffle assembly


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: endoplasmic reticulum membrane ; membrane ; 1-acylglycerophosphocholine O-acyltransferase activity ; 1-acylglycerophosphoethanolamine O-acyltransferase activity ; 1-acylglycerophosphoserine O-acyltransferase activity ; acyltransferase activity ; lipid modification ; phosphatidylcholine acyl-chain remodeling ; phosphatidylethanolamine acyl-chain remodeling ; phosphatidylserine acyl-chain remodeling ; phospholipid biosynthetic process ; regulation of chondrocyte differentiation


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: calcium channel complex ; mitochondrial inner membrane ; mitochondrial intermembrane space ; mitochondrial membrane ; mitochondrion ; uniplex complex ; calcium ion binding ; identical protein binding ; protein heterodimerization activity ; calcium import into the mitochondrion ; calcium ion import ; mitochondrial calcium ion homeostasis ; mitochondrial calcium ion transmembrane transport ; positive regulation of mitochondrial calcium ion concentration ; protein homooligomerization ; regulation of cellular hyperosmotic salinity response


Instruction: Analyze a protein sequence and provide the corresponding Gene Ontology term that best represents its properties.

Input: MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERDRASGYRKRGPKPRRLLLQESAAPDVVQTPGDWEPMEQAPEEEAEADLTNGPPPWTPTLPSSEVTVTDITANSVTVTFREAQAAEGFFRDRNEKL

Output: chromatin ; cytosol ; heterochromatin ; nucleoplasm ; nucleus ; PcG protein complex ; PRC1 complex ; chromatin binding ; methylated histone binding ; single-stranded RNA binding ; chromatin organization ; negative regulation of transcription by RNA polymerase II ; positive regulation of transcription elongation by RNA polymerase II ; sebaceous gland development


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: cytoplasm ; nucleus ; identical protein binding ; metal ion binding ; spermatid development


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Input: MNHTSQAFITAASGGQPPNYERIKEEYEVAEMGAPHGSASVRTTVINMPREVSVPDHVVWSLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDVTGAQAYASTAKCLNISTLVLSILMVVITIVSVIIIVLNAQNLHT

Output: apical part of cell ; cell surface ; cytoplasm ; cytoplasmic vesicle ; early endosome membrane ; endoplasmic reticulum ; late endosome membrane ; lysosomal membrane ; nucleus ; perinuclear region of cytoplasm ; plasma membrane ; protein-containing complex ; defense response to virus ; negative regulation of cell population proliferation ; negative regulation of viral entry into host cell ; negative regulation of viral genome replication ; negative regulation of viral transcription ; receptor-mediated endocytosis ; response to interferon-alpha ; response to interferon-beta ; response to type II interferon ; response to virus ; type I interferon-mediated signaling pathway


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: cilium ; cytoplasm ; protein-containing complex binding ; cell projection organization ; heterotrimeric G-protein complex assembly ; negative regulation of protein refolding ; positive regulation of smoothened signaling pathway ; protein folding ; regulation of G protein-coupled receptor signaling pathway ; response to stimulus ; visual perception


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: axon ; cytoplasm ; cytosol ; dendrite ; mitochondrion ; neuronal cell body ; flavin adenine dinucleotide binding ; protein homodimerization activity ; protein-containing complex binding ; thioredoxin-disulfide reductase activity ; cell redox homeostasis ; heart development ; hemopoiesis ; response to oxygen radical


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: chloroplast ; chloroplast outer membrane ; cytosol ; chloroplast organization ; chloroplast relocation


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Output: cytosol ; phosphatidic acid binding ; phosphatidylinositol phosphate phosphatase activity ; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity ; protein tyrosine phosphatase activity ; dephosphorylation ; peptidyl-tyrosine dephosphorylation ; phosphatidylinositol dephosphorylation ; response to osmotic stress ; response to salt stress


Instruction: Use the Gene Ontology project to assign the appropriate term for the cellular component, molecular function, and biological process of a given protein sequence.

Output: chloroplast ; chloroplast envelope ; chloroplast thylakoid ; chloroplast thylakoid membrane ; chloroplast thylakoid membrane protein complex ; cytosol ; photosynthetic electron transport in photosystem II


Instruction: Use the Gene Ontology project to assign the appropriate category for the molecular function, biological process, and cellular component of a given protein sequence.

Output: membrane ; plasmodesma ; ATP binding ; protein serine kinase activity ; protein serine/threonine kinase activity ; protein phosphorylation ; regulation of pollen tube growth


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: cytosolic ribosome ; endoplasmic reticulum ; endoplasmic reticulum membrane ; membrane ; fatty acid elongase activity ; very-long-chain 3-ketoacyl-CoA synthase activity ; cellular response to cold ; response to cold ; response to light stimulus ; very long-chain fatty acid biosynthetic process ; wax biosynthetic process


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: cation channel complex ; dendrite membrane ; endomembrane system ; endoplasmic reticulum membrane ; Golgi membrane ; nuclear envelope ; plasma membrane ; damaged DNA binding ; diacylglycerol binding ; inositol 1,4,5 trisphosphate binding ; store-operated calcium channel activity ; acrosome reaction ; calcium ion transmembrane transport ; calcium ion transport ; female courtship behavior ; inter-male aggressive behavior ; mating behavior, sex discrimination ; negative regulation of male mating behavior ; positive regulation of cytosolic calcium ion concentration ; regulation of cytosolic calcium ion concentration ; regulation of gene expression ; response to pheromone ; single fertilization ; single strand break repair ; territorial aggressive behavior


Instruction: Determine the GO term that accurately describes the attributes of a given protein sequence.

Output: chloroplast ; chloroplast stroma ; cytosol ; aspartate kinase activity ; ATP binding ; homoserine dehydrogenase activity ; NADP binding ; aspartate family amino acid biosynthetic process ; homoserine biosynthetic process ; lysine biosynthetic process via diaminopimelate ; methionine biosynthetic process ; phosphorylation ; threonine biosynthetic process


Instruction: Find the Gene Ontology term that matches the attributes of a given protein sequence.

Input: MNSLHAHLLLLAVCCVGYIASSPVIGQDQRSGDSDADVLLAADEMADNGGDNIDKRVERYAFGLGRRAYMYTNGGPGMKRLPVYNFGLGKRSRPYSFGLGKRSDYDYDQDNEIDYRVPPANYLAAERAVRPGRQNKRTTRPQPFNFGLGRR

Output: extracellular space ; hormone activity ; neuropeptide hormone activity ; neuropeptide receptor binding ; signaling receptor binding ; negative regulation of juvenile hormone biosynthetic process ; neuropeptide signaling pathway


Instruction: Predict the specific  Gene Ontology term that represents the characteristics of a given protein sequence.

Output: apical dendrite ; calyx of Held ; clathrin-coated pit ; cytoplasm ; dendritic spine ; endocytic vesicle ; glutamatergic synapse ; intracellular vesicle ; lamellipodium ; neuronal cell body ; nuclear envelope ; plasma membrane ; postsynaptic actin cytoskeleton ; presynaptic endocytic zone ; presynaptic membrane ; recycling endosome ; synapse ; terminal bouton ; calcium ion binding ; guanyl-nucleotide exchange factor activity ; kinase activator activity ; molecular adaptor activity ; proline-rich region binding ; brain development ; clathrin-dependent synaptic vesicle endocytosis ; endosomal transport ; exocytosis ; negative regulation of neuron apoptotic process ; neuron apoptotic process ; positive regulation of caveolin-mediated endocytosis ; positive regulation of dendritic spine development ; positive regulation of growth hormone secretion ; positive regulation of protein kinase B signaling ; protein localization ; protein transport ; regulation of modification of postsynaptic actin cytoskeleton ; regulation of postsynapse organization ; small GTPase mediated signal transduction ; synaptic vesicle endocytosis


Instruction: The Gene Ontology project (GO) provides a controlled vocabulary to describe gene and gene product attributes in any organism. There are 3 disjoint categories: cellular component, molecular function and biological process. Predict the GO term for a given protein sequence.

Output: centrosome ; cytoplasm ; intracellular vesicle ; plasma membrane ; presynaptic membrane ; calcium ion binding ; guanyl-nucleotide exchange factor activity ; molecular adaptor activity ; cell differentiation ; clathrin-dependent synaptic vesicle endocytosis ; endosomal transport ; positive regulation of dendrite extension


Instruction: Given a protein sequence, predict the corresponding Gene Ontology term that describes its molecular function, biological process, and cellular component.

Output: chloroplast stroma ; cytosol ; mitochondrion ; agmatinase activity ; arginase activity ; cobalt ion binding ; defense response to fungus ; ornithine metabolic process ; proline metabolic process ; putrescine biosynthetic process ; putrescine biosynthetic process from arginine, using agmatinase ; putrescine metabolic process ; tyrosine metabolic process ; urea cycle


Instruction: Determine the GO term that accurately describes the gene and gene product attributes of a given protein sequence.

Output: dendritic spine ; glutamatergic synapse ; postsynaptic density ; ATP binding ; calcium ion binding ; calmodulin binding ; elongation factor-2 kinase activity ; translation factor activity, RNA binding ; translation regulator activity ; cellular response to anoxia ; cellular response to brain-derived neurotrophic factor stimulus ; cellular response to calcium ion ; cellular response to cAMP ; cellular response to insulin stimulus ; myosin II filament disassembly ; negative regulation of apoptotic process ; positive regulation of dendritic spine morphogenesis ; positive regulation of endocytosis ; positive regulation of synapse assembly ; protein autophosphorylation ; regulation of protein autophosphorylation ; regulation of translation at postsynapse ; response to ischemia ; response to prolactin ; translational elongation


Instruction: Identify the appropriate Gene Ontology term that corresponds to the molecular function, biological process, and cellular component of a given protein sequence.

Output: membrane ; alkane 1-monooxygenase activity ; aromatase activity ; heme binding ; iron ion binding ; defense response ; fatty acid metabolic process


Instruction: Analyze a protein sequence and predict the Gene Ontology category that best represents its attributes.

Output: cytoplasm ; 4 iron, 4 sulfur cluster binding ; lipoate synthase activity ; metal ion binding ; lipoate biosynthetic process ; protein lipoylation


Instruction: Predict the specific Gene Ontology term that best represents the properties of a given protein sequence.

Output: nucleoplasm ; nucleus ; DNA-binding transcription factor activity ; DNA-binding transcription factor activity, RNA polymerase II-specific ; DNA-binding transcription factor binding ; DNA-binding transcription repressor activity, RNA polymerase II-specific ; double-stranded DNA binding ; double-stranded telomeric DNA binding ; mRNA binding ; mRNA regulatory element binding translation repressor activity ; purine-rich negative regulatory element binding ; RNA binding ; RNA polymerase II transcription regulatory region sequence-specific DNA binding ; single-stranded DNA binding ; SMAD binding ; DNA unwinding involved in DNA replication ; negative regulation of DNA-templated transcription ; negative regulation of transcription by RNA polymerase II ; regulation of transcription by RNA polymerase II


Instruction: The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function, Biological process, Cellular component. Predict the GO term for a given protein sequence.

Output: cytoplasm ; nucleoplasm ; nucleus ; poly(ADP-ribose) glycohydrolase activity ; ATP generation from poly-ADP-D-ribose ; Cajal body organization ; carbohydrate metabolic process ; female germ-line stem cell population maintenance ; heterochromatin formation ; maintenance of protein location in nucleus ; nucleotide-sugar metabolic process ; regulation of DNA repair ; regulation of RNA splicing ; response to heat