[
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH",
    "output": "AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAEMTVELVAVERRLWSGSATLVSAQTTEGEIGVMPGHEPVLGQLVEAGVVAITTADGERIVAAVHGGFLSVTAKTVTILAESADLAEDIDVEAAKAVLAESGDDLEAIAVAKGRIRAVERA",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSLSTSFDSSSDLPRSKSVDNTAASMKTGKYPKLENYRQYSDAQPIRHEALALKVDETKDSRHKFSSSNGENSGVENGGYVEKTNISTSGRMDFEGEAEAEAVKRYQLRSFALLSSNARPSRLAKSETHQKQIHVESIAPSLPKNAALERGHDTALPAGTSSNRCNLEASSSARTFTSARKASLVSAIFETSAESEHGTHPKQAKLKRRTYSTISTHSSVNPTTLLTRTASQKSDMGNDTRRIKPLRMDSRVSFHSEISQASRDSQETEEDVCFPMFRLLHTRVNGVDFDELEEYAQISNAERNLSLANHQRHSERTYNHTDQDTGFTNSASTSGSSAALKYTPEISRTLEKNCSVNEMYVSENNESVREDDKPDLHPDVTFGRNKIEGEKEGNDSSYSRAYYTLQNTEYQIPSRFSFFRSESDETVHASDIPSLISEGQTFYELFKGGDPTWWLDCSCPTDDEMRCIAKTFGIHPLTAEDIRMQETREKVELFKSYYFVCFHTFENDKESENYLEPINVYIVVFRSGVLTFHFDPISHCANVRRRVRQLRDYVSVNSDWLCYALIDDITDSFAPVIQSIEYEADSIDDSVFMTRDMDFAAMLQRIGESRRKTMTLMRLLSGKADVIKMFAKRCQDETNGIGPVLKSQTNMVNLQAEQENVNQNNSNNQISLSNSYMQTTSQPRGDIALYLGDIQDHLLTMFQNLLAYEKIFSRSHANYLAQLQVESFNSNNKVTEMLGKVTMLGTMLVPLNVITGLFGMNVKVPGRNGSIAWWYGILGVLLLLAVISWFLASYWIKKIDPPATLNEAAGSGAKSVISSFLPKRDKRFNDDSKNGNARVGVRRKSTVSLPSRYSRYN",
    "output": "Plasma membrane magnesium transporter."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIRIGQGFDVHQLVPQRPLIIGGVTLPYEKGLLGHSDADVLTHAIIDAILGAAGLGDIGQLFPETDPQFKNANSVNLLKKVNEKVGRSGFTIGNIDCTILAEEPKMSPYLAEMKKNLAASCHLAVTQVNIKATTMETMGFVGKKEGIGAIAVALLEK",
    "output": "Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQDQLICSGCRRVVQYRRGVAGVCCPGCNTLTAVNPSAVADMSELICSGCPTLLFYNRGASNIRCPSCNRLNSTRSANQIAHLTCGQCRTTLMHPPGASTVQCATCRYVNHVRDARPQTVLVENPKTLDDKGKLVSNVVVGVTSWKR",
    "output": "Putative zinc finger that may be involved in programmed cell death and defense response."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MYLDHLTVQNFRNLKKLDVDFDPNVNIFIGKNAQGKTNLLEAIYFLALTRSHRTSSDRDLIGFDGEYTNLAGHVQKSQVTLNLRVLITKKGKKVWINRIEQAKLSKYVGQLNAILFSPEDLELIKGAPSLRRRFMDQEFGQINAEYLYFASKYRQVLIQKNNYLKQLAKGKAKDQVFLDVLSDQLAGIAAELIYRRFKFLTYLSHYASDAYTHISLGSEKLSIAYHPSVSDITADDTTEEIYQKILNSFNRNKASEIRKGTTTSGPHRDDIEFKLDGKNAHLYASQGQQRSIALSIKLAEIQLVHQLTDEYPLLLLDDVMSELDHGRQSALLNYIHGKTQTFITTTDLEGISWDIIKKPRVYHIQSGTISLEKEN",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLTLAHYLVLGAILFAIAIVGIFLNRRNVIIILMSIELMLLAVNTNFVAFSHYLGDVHGQIFVFFVLTVAAAEAAIGLAILVTLFRKLDTINVEDLDQLKG",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD",
    "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAQKENTYPWPYGRQTAQSGLNILPQRVLRKEAVTPSALVLMSRSNTQPTAAPGQKVVENSSGTPNFSTRSFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLQHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKCRTFDEQRTATIMEELADALIYCHGKKVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRTHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIGKVDLKFPPSVPAGAQDLISKLLKHNPSDRLPLAQVSAHPWVRAHSRRVLPPSAPQSVP",
    "output": "Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1, SEPTIN1, VIM/vimentin, HASPIN, and histone H3. A positive feedback loop involving HASPIN and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at 'Ser-10' and 'Ser-28' during mitosis (H3S10ph and H3S28ph, respectively). AURKB is also required for kinetochore localization of BUB1 and SGO1. Phosphorylation of p53/TP53 negatively regulates its transcriptional activity (By similarity). Key regulator of active promoters in resting B- and T-lymphocytes: acts by mediating phosphorylation of H3S28ph at active promoters in resting B-cells, inhibiting RNF2/RING1B-mediated ubiquitination of histone H2A and enhancing binding and activity of the USP16 deubiquitinase at transcribed genes (By similarity). Acts as an inhibitor of CGAS during mitosis: catalyzes phosphorylation of the N-terminus of CGAS during the G2-M transition, blocking CGAS liquid phase separation and activation, and thereby preventing CGAS-induced autoimmunity (By similarity). Phosphorylates KRT5 during anaphase and telophase (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQACEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESASAKIKEEEAAKD",
    "output": "Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Probably forms a corepressor complex required for activated KRAS-mediated promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) or other tumor-related genes in colorectal cancer (CRC) cells . Also required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs) . Associates at promoter regions of tumor suppressor genes (TSGs) leading to their gene silencing . Promotes tumor growth ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIYIVALTGGICSGKTTVSDRFKKIGINVIDTDVIGRKIIEKNKKISDSIKKKFGKKILNKDNSINRFLLRNCIFNEKKSRLWLENILHPEILKKSKKKIKLIQSTWCLWVVPLLFEKKIQKKANRILLIDTPIRIQIRRMIKRDKININEAKKIISYQVRRKKRISLSDDIILNKNKNIEKLSLYIHYLNNFYIYLSKQNNPKNMKKII",
    "output": "Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKVDLNKETGPREVFCGLTSIVWLHRRMPDAFFLVVGSRTCAHLIQSAAGVMIFAEPRFGTAILEEKDLAGLADAHEELDRVVNDLISRRPEIKTLFLVGSCPSEVIKLDLATVAEKLNSRFLGQVRFVNYSGSGIETTFTQGEDGALKALVPLMESTDDEKLLLVGTLANNVEDRFKKIFNNIGITNVESFPPRQSTELPKIGKNTKVLLAQPYLSDTVRDLKHRGCGIIQAPFPLGVEGSTKWVLAAAAAFKIHELKVHEVIAPLANRARQAIEKHKEILRGKKLFLLPESQLEISLARFLHNECEMELIEVGTPYLNRDLMEEELNLLPDDTKIVEGQHVEKQLDRVRASNPDLVVCGMGLANPLEAEGISTKWSIEMVFSPIHGIDQAADLAGLFSRPLTRNQILTSKSLATH",
    "output": "Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE",
    "output": "Major urinary proteins (Mups) bind pheromones, and thus stabilize them to allow slow release into the air from urine marks. May protect pheromones from oxidation. May also act as pheromones themselves. In this context, they play a role in the regulation of social behaviors, such as aggression, mating, pup-suckling, territory establishment and dominance (Probable). Binds the pheromone analog 2-sec-butyl-4,5-dihydrothiazole (SBT) in vitro ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEGISALEKNVAELTVMDVYDIASAVGQEFERVIDQYGCEVIGRLMPKVVRVLEILEVLVSRNHINPEMEELRLELDRLRLERMDRIEKEKKHQKELELVEDVWRGEAQDLLNQIAQLQEENKQLVSNLSQKDINLTEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELVLKNEDVEALQQQQSRLMKINHDLRHRVTVVEAQGKALIEQKVELEAYLQTKEQEAASMRLEIGKLRDKLKGEQHTNGEEIKTETLNEESILETEKLSLDLKDSNRPRFTLQELRDVLHERNELKAKVFMLQEELAYYKSEEADEEHKLPQSSPVIDSKAPIPQESGIKRLFSFFSRDKKRMPMMQKNVHFQESFGQWTEYNRDDVYTEQGQEALQHM",
    "output": "Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDVSILRDVRPPVTSYAPNIWADTFSNISLDEEVQKKYAETIEALKQVVRGMLMAAATPIKQMIFIDTLERLGLAYHFETEIEHKLQKIYDDNVCGDDCDLFTTALRFRLLRQHRHHVSCDVFDKFLYEEGKFKGDAEGLLSLYEASHVRFHNEKILEEAERFTRQELSCWIKLQSPLKDKVKRALERPLHREVPILYARHFISIYEKDESMDEHLLKLAKFNFNFLQNLYKKELYDLSRWWNKFDLKTKLPYIRDRLAEAYLWGVGYHFEPQYSYVRKGVVLSIKIIGILDDTYDNYATVNEAQLFTEILDRWSMDEIDRLPDYMKIVLHFVMSAYEEYERDAKIVYGKKFASPYFKETIQQLARGYNQELKWVMEKQMPPFKDYLKNSEITSCIYIMFASIIPGLKSFTQEAIDWIKNEPNFAVKAGLIGRYWDDIGSHKRESKGGEMLTVMDCYMKQYSVSIQETISEFAKAVEDSWKEVNEGWVYTISMSKEITVQFLNYSRMCDASYNRNNGDGYTDPSFAKSNITALFVDPIII",
    "output": "Sesquiterpene synthase that catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to gamma cadinene."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAPGQNRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRNMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSYFAVIERASIDEAYIDLTSAVQERLQKLQGQPISADLLPSTYIEGLPRGPTVEETVQKEAIRKQGLLQWLDSLQSDDPTSPDLRLTVGAMIVEEMRAAIESKTGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEVLGIEYMGDLTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLALELEERLTKDRNDNDRVATQLVVSIRFQGDRRLSSLRRCCALPRYDAHKMSQDAFAAIRNCNTSGIQTEWSPPLTMLFLCATKFSAAAPPACTDITAFLSSDSSCQPKVPIASSETRTQGSGPAVPTSKEAATSLASFFQKAAKKQRMKETSFVPLNTATEKLSSKPSLVFQSSQTTGSQSFFKQKSLLLQHTQLSNSAAPDPPQASPAAQPSCLPAECVDSGPDDGAVKPVSSKAVSTEMNVAGDSPNVLDSPAYNSQEVTQRATEDQVLCEKCDSLVPVWDMPEHTDYHFALELQKSFLQPCTSKPQAIPAVSPQGKRNPKSPSASSSKRLRPHGMQTLESFFKPLTH",
    "output": "DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS) . Due to low processivity on both damaged and normal DNA, cooperates with the heterotetrameric (REV3L, REV7, POLD2 and POLD3) POLZ complex for complete bypass of DNA lesions. Inserts one or 2 nucleotide(s) opposite the lesion, the primer is further extended by the tetrameric POLZ complex. In the case of 1,2-intrastrand d(GpG)-cisplatin cross-link, inserts dCTP opposite the 3' guanine (By similarity). Particularly important for the repair of UV-induced pyrimidine dimers . Although inserts the correct base, may cause base transitions and transversions depending upon the context. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have any lyase activity, preventing the release of the 5'-deoxyribose phosphate (5'-dRP) residue. This covalent trapping of the enzyme by the 5'-dRP residue inhibits its DNA synthetic activity during base excision repair, thereby avoiding high incidence of mutagenesis. Targets POLI to replication foci (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDVLTLPAYGKINLTLKVLGRRSDGYHNLSTIFQSIALADRLTFSRCREGIRLETSGLPVPQGPENLAYRAAARLQSRYGFPGVRITLKKQIPLAAGLAGGSADAAATLIGVNALFNLGLTPGQLAREGAALGSDVPFCVIGGTALGRGRGEELSLLPPLPTLWLVLVKPSFGVSTAAVYRGWDASPGQTPMEAPDEERALAAIRRGDRAGIMASLGNDLEAVTCRLYPEVMAIKMRLLAEGAERAVMCGSGPAVFGVAADGETARRIASRLQETYPETIVTRTL",
    "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLHRYLPMTEEDKKEMLQTIGVQTIDELFSDIPESVRFKGDLKIKEAKSEPELLKELSQMASKNANLKEYASFLGAGVYDHYAPVIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMICELTGMDVANSSMYDGGTALAEAAMLAAGHTRKKKILVSSAVHPESRAVLETYAKGQHLEVVEINHKDGVTDLDVLQSEVDDTVACVIVQYPNFFGQVEKLADIEKIVHQQKSLFIVSSNPLSLGALTPPGKFGADIVIGDAQPFGIPTQFGGPHCGYFATTKAFMRKIPGRLVGQTVDSDGKRGFVLTLQAREQHIRRDKATSNICSNQALNALAASVAMTALGKQGVKEMARQNISKAQYAKRQFEAKGFTVTFAGPFFNEFVVDCKRPVKEVNDALLQKNIIGGYDLGRDYKEHENHMLVAVTELRTKEEIDTLVNEMGAIQ",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKKQIISLGALAVASSLFTWDNKADAIVTKDYSKESRVNENSKYGTLISDWYLKGRLTSLESQFINALDILETYHYGEKEYKDAKDKLMTRILGEDQYLLERKKVQYEEYKKLYQKYKEENPTSKGLKLKTFDQYTIEDLTMREYNELTESLKSAVKDFEKDVEKIENQHHDLKPFTDEMEEKATSRVDDLANKAYSVYFAFVRDTQHKTEALELKAKVDLVLGDEDKPHRISNERIEKEMIKDLESIIEDFFIETGLNKPGNITSYDSSKHHYKNHSEGFEALVKETREAVANADESWKTKTVKKYGESETKSPVVKEENKVEDPQSPKFDNQQEVKTTAGKAEETTQPVAQPLVKIPQGTITGEIVKGPEYPTMENKTLQGEIVQGPDFPTMEQSGPSLSDNYTQPTTPNPILEGLEGSSSKLEIKPQGTESTLKGIQGESSDIEVKPQATETTEASQYGPRPQFNKTPKYVKYRDAGTGIREYNDGTFGYEARPRFNKPSETNAYNVTTNQDGTVSYGARPTQNKASETNAYNVTTHANGQVSYGARPTQKKPSETNAYNVTTHANGQVSYGARPTYNKPSETNAYNVTTHGNGQVSYGARPTYKKPSKTNAYNVTTHANGQVSYGARPTQNKPSETNAYNVTTHANGQVSYGARPTQNKPSETNAYNVTTHGNGQVSYGARPTYNKPSKTNAYNVTTHADGTATYGPRVTK",
    "output": "Staphylocoagulase is an extracellular protein which specifically forms a complex with human prothrombin. This complex named staphylothrombin can clot fibrinogen without any proteolytic cleavage of prothrombin."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVLIRVLANLLLLQLSYAQKSSELVIGGDECNINEHPFLAFVTSDRRRCAGTLINQEWVLTAAHCNGKYMKIELGVHDKMVRNEDKQTRVPKQKFFCLSSKEYTMWDKDIMLIRLNTPVNNSTHIAPVSLASRPPVVGSVCRIMGWGTISSPKVILPDVPHCANIEIIKYSKCQGVHPELPAKGRVVCAGIWQGGKDSCHGDSGAPLICNGQLQGLLSWGGDPCAQPLQPGLYTDIFDYSDWIQSIIAGNTTATCPP",
    "output": "Snake venom serine protease that may act in the hemostasis system of the prey."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNIITTTTTDTTTALLRLMAWLSPVFPVGSFSYSHGLERAVHDGYVADTATMSDWLRWLVTRGSGWNDAVLCAESWRRAVAKGDLVEVAELAEALAGSRERHMETMLQGEAFLAAARSWPSSVFDRLPADCPYPVAVGAVAGANKVSLGLTLAAFLQAFCINLLQASIRLSVMGQNGVTATMSDLEPVLAETATRIEKTSLSDLGSATYISDIMAMKHETQHSRLFRT",
    "output": "Required for maturation of urease via the functional incorporation of the urease nickel metallocenter."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDKNFYKNSLNIFNSNFSMKANLSEKDKFYADFWEKNQIYQQILRKRRGNPRFILHDGPPYANGDIHIGHALNKILKDIIVRYKTMAGFYSPFVPGWDTHGLPIENKIINQIGSKSTLEIRRKSNDFANSQILAQMKQFKKLNLLTDFKQIYQTNTPNYEAKQLKLFKKMVSRGLVYRALKPVYWSPSSQSALAEAEIEYLEYRSPSLFTSFDIKKGNNFVAENDKLIIWTTTPWTLIANSGVAVGENFDYVRIKNGENFYVLAANLLEKLAVIFDWKHYEIIDNFPGRAILGIKYLHPIFEKICPIVSGNHVSLDVGSGLVHLAPLFGEDDYWIGRENNLEMVMHVNDDGKFNENAGQFSGQFYADSNKLITEFLEKKSKILHLSFIDHSFPHDWRTLKPVIYRGTPQWFVSIEKIKKDLEKAIEEIEFPENWLKKRLTKMVVERKDWLISRQRSWGIPLIIFYDQNKDPVLDKPEIFDYIISLVEKFGSRIWYEKTTDELLPEKYQNLGWTKENDILDVWFDSGVSFFAANISDEKPPFDIYFEGSDQYRGWFNSSLINSVIYFGFSPYKKLLSHGFVVDAKGNKMSKSRGNGVDPLLILSKYGCDIFRLWVANSEYYNDIVYSEAIFEQNVEIYRKIRNTVRFLITNLADFKPTKYELTEVDLYIFNKIQKLKNEIIQNYDQNRFVRVVKIINNFIIEFSNFYLSIVKDILYADKKESLKRRQVQYNLYELLQVLNIAIAPIMPTTAEEIYSFIQKNNKQISVHMEEFFKESHFDEELDAKWNEFFQIKDSVYQLIEQKIKSKEIKRPNEVGVLLKTDSDFIKSIDLKKLLMVAKVEFSNGKTEILQLNWEKCPRCWNHFEKINKVCARCFEVLSEIVPEKNS",
    "output": "Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRRAEVARLIDHTLLAPAATDEEVLALCAEAARLGVGAVCVAPTHVYLAAASTYRSSHEAEPAFAVASVIGFPHGTHLTVIKAEEARRAVADGATEIDMVIDIANALDENWRAIETEISEVRLSVPPHVILKVILETALLPDANIIAACRAAEAGGAEFVKTSTGFHPAGGASVRAVRAMAEAVGGRLGIKASGGIRTAEKAKDMLEAGATRLGLSASADVLAGFPA",
    "output": "Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MREIVHVQGGQCGNQIGAKFWEVISDEHGVDPTGTYHGDSDLQLERINVYYNEATGGRYVPRAVLMDLEPGTMDSVRAGPYGQLFRPDNFIFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAEGCDCLQGFQITHSMGGGTGSGMGTLLIAKVREEYPDRMMCTYSVFPSPKVSDTVVEPYNATLSVHQLVENADEVMVIDNEALYDICFRTLKLTTPTYGDLNHLVSACISGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMIGFVPLTSRGSQQYRALTVPELTQQMFDAKNMMCAADPRHGRYLTASALFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNIKASVCDIPPKGLKMSATFIGNSTAIQEMFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEGDEEEAEGEAAA",
    "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MISSRIGGAGGVELSRVNQQHDTVPAQTAHPNAVTAGMNPPLTPDQSGSHATESSSAGAARLNVAARHTQLLQAFKAEHGTAPVSGAPMISSRAALLIGSLLQAEPLPFEVMAEKLSPERYQLKQFQGSDLQQRLEKFAQPGQIPDKAEVGQLIKGFAQSVADQLEHFQLMHDASPATVGQHAKADKATLAVSQTALGEYAGRASKAIGEGLSNSIASLDEHISALDLTLQDAEQGNKESLHADRQALVDAKTTLVGLHADFVKSPEAKRLASVAAHTQLDNVVSDLVTARNTVGGWKGAGPIVAAAVPQFLSSMTHLGYVRLSTSDKLRDTIPETSSDANMLKASIIGMVAGIAHETVNSVVKPMFQAALQKTGLNERLNMVPMKAVDTNTVIPDPFELKSEHGELVKKTPEEVAQDKAFVKSERALLNQKKVQGSSTHPVGELMAYSAFGGSQAVRQMLNDVHQINGQTLSARALASGFGGAVSASSQTLLQLKSNYVDPQGRKIPVFTPDRAESDLKKDLLKGMDLREPSVRTTFYSKALSGIQSSALTSALPPVTAQAEGASGTLSAGAILRNMALAATGSVSYLSTLYTNQSVTAEAKALKAAGMGGATPMLDRTETALNNIRHPNRESLPHTFQKSTLSGIPRVAENAYHMGRGALQLPTQMAVDTVRVVDEGVLNAVASAREALKQPTKDDDALRALEEGLLDPR",
    "output": "Involved in the suppression of basal resistance and promotion of disease symptoms in plants. Mediates the ubiquitination and degradation, via the host proteasome, of a low-abundance immunity-associated protein in Arabidopsis thaliana. May be involved in the inhibition of a host vesicle trafficking pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAGRKGGRAKRRKVCFFTSNGITRIDYKDVDLLKRFVSERGKILPRRVTGTSAKYQRKLTVAIKRARQMALLPYVGE",
    "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQLRDLAPRSPNVAAPPYNGLPPPHLLLGYQAMHRALNDYLFDNRVFMQIGYDSPPQRPRRLFWTCLTDCSYAVNVGQYMRFLDLDNFHGTFTQMHNAVLMDRVAADMGRAHLRGRGIDVGRHGQVLPQLDAEHHSLLSGNGAGGLQEGVLMRTASAADAELLAAIRQLRVALCHYLFCYAYDLFQTEERYRFLPGSDVFLEPNWLSYFAEAFAELDTQQLVRDAERKFRGRRDVEEPTETMARCFMSTLASDAVSLAGTGLSGGAITLCSRRVTDRTGLRPRDRHGRAITASEARRIRPRAVRAFVDRLPRVTRRRRRPPSPAPPPEEIEEAAMEVEEPEEEEEELLDEVIRTALEAIGALQDELSGAARRHELFRFANDFYRMLLTARDAGLMGESFLRKWVLYFFLAEHIASTLYYLYSHFIANREFRRYVDVLTLQVLVVGWDVNAQQVFKRIWSEQSNPATIFETLWERILRDFLMMVERTGQFEGMDDADQQLFLSDIQYRDRSGDIEEVLKQLNLSEELIDSIDISFRIKFKGIVAIATNEEIKANLRRVLRHRREDIEAAARRGQPL",
    "output": "Protein covalently bound to the viral DNA that acts as a primer for viral genomic replication by DNA strand displacement. Assembles on the viral origin of replication in an initiation complex with viral polymerase, DBP, host NFIA and host POU2F1/OCT1. During initiation, the polymerase covalently couples the first dCTP with Ser-580 of pTP. The terminal protein stimulates the template activity over 20 fold compared to protein-free templates. Neo-synthesized viral genomes are linked to two preterminal proteins, one for each 5' end. These new genomes are encapsidated in the nucleus, and during capsid maturation by viral protease, preterminal protein is first cleaved into intermediary (iTP), then into mature TP. May play a role in host nuclear matrix localization of genomic DNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MREILHIQGGQCGNQIGAKFWEVVCDEHGIDPTGRYTGNSDLQLERVNVYYNEASCGRFVPRAVLMDLEPGTMDSVRTGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPRGLSMASTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEEEYEDEEEVQADDM",
    "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNNAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVAPSTTMQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNLF",
    "output": "Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQVPGTMPAPVLKGQALWLPLLLMLSPQASGGLVITPPGPELVLNISSTFVLTCSGPAPVVWERLSQEPLQKMARTQDGTFSSTLTLTNVTGLDTGEYFCTYKGSHGLEPDGRKRLYIFVPDPTMGFLPVDPEELFIFLTEITEITIPCRVTDPRLVVTLHEKKVDIPLPIPYDHQRGFSGTFEDKTYVCKTTIGDKEVDSEAYYVYSLQVSSINVSVNAVQTVVRQGENITIMCIVTGNEVVNFEWTYPRMESGRLVEPVTDFLFNVPSHIRSILHIPSAELGDSGTYICNVSESVNDHRDEKSINVTVVESGYVRLLGELDAVQFAELHRSRALQVVFEAYPPPTVVWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGYYTMRAFHEDAEAQLSFQLQVNVPVRVLELSESHPASGEQTVRCRGRGMPQPHLTWSTCSDLKRCPRELPPTPLGNSSEEESQLETNVTYWPEDQEFEVVSTLRLRRVDQPLSVRCTLHNLLGHDMQEVTVVPHSLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQLCSDKRRPPSAELYSNALPAGLPLPSHVSLPGESDGGYMDMSKDESVDYVPMLDMKGGVKYADIESSSYMAPYDNYVPTAPERTCRATLINESPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAVLRSQARLPGFPGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADGPLESSPSLASSTLNEVNTSSTISCDSPLEPQEEPEPEPEPQPEPQVVPEPPLDSSCPGPRAEAEDSFL",
    "output": "Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites. Required for normal development of the cardiovascular system. Required for normal recruitment of pericytes (mesangial cells) in the kidney glomerulus, and for normal formation of a branched network of capillaries in kidney glomeruli. Promotes rearrangement of the actin cytoskeleton and the formation of membrane ruffles. Binding of its cognate ligands - homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFD -leads to the activation of several signaling cascades; the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PLCG1, PIK3R1, PTPN11, RASA1/GAP, CBL, SHC1 and NCK1. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, mobilization of cytosolic Ca(2+) and the activation of protein kinase C. Phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leads to the activation of the AKT1 signaling pathway. Phosphorylation of SHC1, or of the C-terminus of PTPN11, creates a binding site for GRB2, resulting in the activation of HRAS, RAF1 and down-stream MAP kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation and activation of SRC family kinases. Promotes phosphorylation of PDCD6IP/ALIX and STAM. Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalization of the activated receptor (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAHMKTRLVYASILMMGALCLYFSMDSFRELPFVFKKSHGKFLQIPDIDCKQKPPFLVLLVTSSHKQLAARMAIRKTWGRETSVQGQQVRTFFLLGTSDSTEEMDATTLESEQHRDIIQKDFKDAYFNLTLKTMMGMEWVYHFCPQTAYVMKTDSDMFVNVGYLTELLLKKNKTTRFFTGYIKPHDFPIRQKFNKWFVSKFEYPWDRYPPFCSGTGYVFSSDVAIQVYNVSESVPFIKLEDVFVGLCLAKLKIRPEELHTKQTFFPGGLRFSVCRFQKIVACHFMKPQDLLTYWQALENSKEQDCPAV",
    "output": "Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor. Also catalyzes the transfer of Gal to the terminal GalNAc unit of the globoside GB4, thereby synthesizing the glycolipid GB5, also known as the stage-specific embryonic antigen-3 (SSEA-3)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGSEQNDSTSFTQSQASEPKLCVKGCGFFGSPSNMDLCSKCYRGICAEEAQTAVAKAAVEKSFKPSPPRSLFIAEPPAVVVEPKPEKAAVVVVSAEPSSSAVPEANEPSRPARTNRCLCCNKKVGIMGFKCKCGSTFCGEHRYPETHDCSFDFKEVGRGEIAKANPVVKADKIQRF",
    "output": "May be involved in environmental stress response."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "AEKIKICLQKQVNSSFSLHNVFGGNLYATEEKRMFELVKPKAGASVLNQSTWICFGDSRTDQSNSAFPRSADVSAKTAEKFRSLSGGSLMLSMFGPPGKVDYLYQGCGKHKVFYEGVNWSPHAAIDCYRKNWTDIKLNFQKSIYELASQSHCMSLVNALDKTIPLQATKGVAKNCNNSFLKNPALYTQEVKPLEQICGEENLAFFTLPTQFGTYECKLHLVASCYFIYDSKEVYNKRGCGNYFQVIYDSSGKVVGGLDNRVSPYTGNSGDTPTMQCDMLQLKPGRYSVRSSPRFLLMPERSYCFDMKEKGLVTAVQSIWGKGRKSDYAVDQACLSTPGCMLIQKQKPYIGEADDHHGDQEMRELLSGLDYEARCISQSGWVNETSPFTEEYLLPPKFGRCPLAAKEESIPKIPDGLLIPTSGTDTTVTKPKSRIFGIDDLIIGLFFVAIVEAGIGGYLLGSRKESGGGVTKESAEKGFEKIGNDIQILRSSTNIAIEKLNDRISHDEQAIRDLTLEIENARSEALLGELGIIRALLVGNISIGLQESLWELASEITNRAGDLAVEVSPGCWIIDNNICDQSCQNFIFKFNETAPVPTIPPLDTKIDLQSDPFYWGSSLGLAITTPISLAALVISGIAICRTK",
    "output": "Binds to the N-acetyl-9-O-acetylneuraminic acid residues on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HEF2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore. Displays a receptor-destroying activity which is a neuraminidate-O-acetyl esterase. This activity cleaves off any receptor on the cell surface, which would otherwise prevent virions release. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASVTDGKTGIKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGRLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSMDTDPSVLGASKTTRLSDTPPLLQQNCSC",
    "output": "Protein transport. Probably involved in vesicular traffic (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAASSISSPWGKHVFKAILMVLVALILLHSALAQSRRDFAPPGQQKREAPVDVLTQIGRSVRGTLDAWIGPETMHLVSESSSQVLWAISSAISVAFFALSGIAAQLLNALGLAGDYLAQGLKLSPGQVQTFLLWGAGALVVYWLLSLLLGLVLALLGRILWGLKLVIFLAGFVALMRSVPDPSTRALLLLALLILYALLSRLTGSRASGAQLEAKVRGLERQVEELRWRQRRAAKGARSVEEE",
    "output": "May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death . Can form voltage-gated calcium and potassium channels in vitro (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNKGRVTQIMGPVVDVKFDGGKLPEIYNALTVKQSNENGTSINLTFEVALHLGDDTVRTVAMSSTDGLVRGTEVEDTGKAISVPVGDATLGRVFNVLGDAIDLDGEVPADVRRDPIHRQAPAFEELSTKVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYHEMSDSGVIKKTAMVFGQMNEPPGARQRVALTGLTMAEHFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNKGSITSIQAVYVPADDYTDPAPATTFAHLDATTNLERRLTQMGIYPAVDPLASTSRALSPEIVGEEHYEVARQVQQTLQRYKELQDIIAILGMDELSEEDKLVVHRARRIQFFLSQNFHVAEQFTGQKGSYVPVKETVRGFKEILEGKYDDLPEDAFRLVGGIEEVIENAKKMMA",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNSKQITTLWCAVIVEELIRQEAGFFCISPGSRSTPLTLAVASNPKARFRMFPDERSAGFYALGYARATGMPAVLVCTSGTAVANYFPAVVEASADAQPMLVLSADRPFELLECGANQAIRQQNIFGSYTRWSFELPEPGIATPLASLLSTVDHAVRKSLSLPAGPVHLNLPFREPLEPEAPDPGHPWAAPLETWQASGEPWSRFARPLHEPSAESIVTLRELLAQAERPLFVAGSMSNAADGEAVAALAESLGVPLFADLTSGIRLSSDCTPWQLAFQNEAFVERFQPDVVIHFGGHVIGKQPAMALRKQPPLHYVVVREHPGRFDPDHNVTLTLEASPAAVASALEGCREPVPGIRCRDAFSAASGIIDKMACVPELAVSEISAPRIVSSLAGDGHALFVANSMPARDMDLYAAPVAQKPLQVALNRGVSGIDGIISTAAGFSAGLGKPTTLLIGDISFLHDLNALCLLNHPWNPLIVIVLNNHGGSIFSFLPIASQTDRLDECFATPQNFSIESAARTFGIDYACPETNGDFTQLYAEALTTKKSLIIEIRSDREKNLLLHRSLKARLDPVFEKADCSR",
    "output": "Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAREYPLERYRNFGIMAHIDAGKTTTTERILFYTGKNHKMGETHEGASTMDWMEQEAERGITITSAATTTFWQRHEDADFTPDDSERCRFNIIDTPGHVDFTIEVERSLAVLDGAICLLDGNAGVEPQTETVWRQADRYKVPRIVFVNKMDKIGADFFKCVAMIKDRTGGTPCPIALPIGAEDKLEGIVDLIKMEEWVWKGEDLGASWVRQPIRDELQDVAEEWRGKMIELAVEQDDEAMEAYLDGNEPDEATLRKLIRKGTLSLSFFPVMAGSAFKNKGVQPLLNAVVDFLPAPTDVPAYLGFAPGDETETRNIERSASDDQPFSALAFKIMNDPFVGSLTFTRIYSGQLKKGDQMLNATKGKRERVGRMMVMHAINREEIEEAFAGEIIALAGLKETTTGDTLCDPAKPVVLETMTFPEPVIEIAVEPKSKADQEKMGLALQRLAAEDPSFRVETDMESGQTIMKGMGELHLDILVDRMKREFKVEANIGAPQVAYRETISQPAEIDYTHKKQTGGTGQFARVKLQIEPTEPGEGYSFESKIVGGAVPKEYIPGVEKGIKSVMDSGPLAGFPVIDFKVALIDGAFHDVDSSVLAFEIAARAGMREGLKKAGAKLLEPIMRVEVVTPEEYTGSIIGDLTSRRGMVRGQDTRGNANVIDAFVPLANMFGYINNLRSMSSGRAVFTMQFDHYEAVPQNISDEIQKKYA",
    "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKVFDYEDVQLIPNKCIVNSRSECDTTVILGKHAFKMPIVPANMQTIINRSIAEFLAENGYFYIMHRFNGSARIPFVKKMKERQWISSISVGVKKEEYLLIEELAKQGLTPDYITIDIAHGHSNSVIEMIQRIKTHLPETFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKSIRFGATMVMIGSLFAGHEESSGETKIENGIAYKEYFGSASEFQKGEKKNVEGKKIWIQHKGSLKDTLIEMHQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI",
    "output": "Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGARASVLSGGKLDKWEKIQLRPGGKKKYRLKHLVWASRELERFALNPNLLETVEGCRQIIRQLQPSLQTGSEELRSLFNTVATLYWVHQSIQVRDTKEALDKLEEEQNRTQQKTQQGKADKGVSQNYPIVQNLQGQMVHQALSPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKDTINEEAAEWDRMHPVQAGPIPPGQIREPRGSDIAGTTSTLQEQITWMTSNPPIPVGEIYKRWIILGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFFRVLRAEQATQEVKNWMTETLLVQNANPDCRTILKALGSGATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSAVMMQRGNFKGQRRIIKCFNCGKEGHLARNCRAPRKKGCWKCGKEGHQMKDCSERQANFLGKFWPLNKERPGNFLQNRPEPTAPPAESFGFGEKITPSLRQEMKDQEQGPPLTSLKSLFGSDPLSQ",
    "output": "[Gag polyprotein]: Mediates, with Gag-Pol polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi).; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEEYSWENFLNDKLLATNQVSAAGLASEEDGVVYECVATPDENNPDFDKWSLFYKEDYDIEIEDENGSKTTKTITEGQSILTMFNEGYASDGIWLGGTKYQFINMDKGLEYEGHSFDVATCAKSKGGMHIIKVGGGHILIVLYDEEKEQDRGNSKNAALAFSKELIESTDTGAA",
    "output": "Essential for the invasive blood stages of the parasite. Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton. Weakly sequesters actin monomers (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSVLTEKDEILADVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYCSVLQAFLDRKDSCYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSALAVHVAMDNTVVMADIRRLCRSSLPCAGAEAFPADSERHCNGFPAGAEGGGRAAPWRPLVLLIPLRLGLADVNAAYAGTLKHCFRMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVAAADRCPVPDESFHCQHPPGRMSIAELDPSIAVGFFCETEDDFNDWCQQVSKLSLLGGALPMFELVEQQPSHLACPDVLNLSLDSSDAERLERFFDSEDEDFEILSL",
    "output": "Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins. Required for canonical autophagy (macroautophagy), non-canonical autophagy as well as for mitophagy. The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Protease activity is also required to counteract formation of high-molecular weight conjugates of ATG8 proteins (ATG8ylation): acts as a deubiquitinating-like enzyme that removes ATG8 conjugated to other proteins, such as ATG3. In addition to the protease activity, also mediates delipidation of ATG8 family proteins. Catalyzes delipidation of PE-conjugated forms of ATG8 proteins during macroautophagy. Also involved in non-canonical autophagy, a parallel pathway involving conjugation of ATG8 proteins to single membranes at endolysosomal compartments, by catalyzing delipidation of ATG8 proteins conjugated to phosphatidylserine (PS). Compared to other members of the family (ATG4A, ATG4C or ATG4C), constitutes the major protein for proteolytic activation of ATG8 proteins, while it displays weaker delipidation activity than other ATG4 paralogs. Involved in phagophore growth during mitophagy independently of its protease activity and of ATG8 proteins: acts by regulating ATG9A trafficking to mitochondria and promoting phagophore-endoplasmic reticulum contacts during the lipid transfer phase of mitophagy.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVAEDAPVRGTCRVLFRTTTLIFLCTLLALSISILYESLIIRKQIMSQAGSTGSNFRLGSITDLLNNILSVANQIIYNSAVALPLQLDTLESTLLTAIKSLQTSDKLEQNCSWGAALINDNRYINGINQFYFSIAEGRNLTLGPLLNIPSFIPTATTPEGCTRIPSFSLTKTHWCYTHNVILNGCQDHVSSNQFVSMGIIEPTSAGFPSFRTLKTLYLSDGVNRKSCSISTVPGGCMMYCFVSTQPERDDYLSTAPPEQRIIIMYYNDTIVERIINPPGVLDVWATLNPGTGSGVYYLGWVLFPTYGGVIKDTSLWNNQANKYFIPQMVAALCSQNQATQVQNAKSSYYSSWFGNRMIQSGILACPLQQDLTNECLILPFSNDQVLMGAEGRLYMYGDSVYYYQRSNSWWPMTMLYKVTITFTNGQPSAISAQNVPTQQVPRPGTGDCSATNRCPGFCLKGVYADAWLLTNPSSTSTFGSEATFTGSYLNAATQRINPTMYIANNTQIISSQQFGSSGQEAAYGHTTCFRDTGSVMVYCIYIIELSSSLLGQFQIVPFIRQVTLS",
    "output": "Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity).; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGQKKKKLAKGRLDKFYYMAKEQGYRSRAAFKLIQLNKKYNFLGTAKACLDLCAAPGGWMQVASKYMPVQSLIVGVDLVPIRQVRNCIGLTEDITTQKCRTEIKKALKTWKVDVCLHDGAPNMGTSWVQDAYQQAELTLHALKLATEFLTTGGWFVTKVFRGSDYNSLIWVFNKLFKKVESTKPPSSRNASAEIFVVCQGFLNPKRIDPKLLDPKFVFKEIQEVKKVDVLSEKKKVNRAGYEDGVTVLYKKGFISDFVNSNEHLQDLANFNAFEFDEAAKIFEQHELTTPEIKELVKDLKVLNKNDFQKIIKWKKAMAAYKEKLDNPDEEETEKPEEKKELTAEEMEENLQEEMKEYLALVEKKKRKEKKRQNELKRKHQRKIELTMHIPGDKIEETTDGDLYSMKGKDEFDEDIVADHSDISSDEFDSDDSDDDDDDDNNGDSKLIDDDEYLEQQLDEQYKLYQQRIRKKAAKLDDVKVKKDKIGQDGYNEDDEEFVEEQEESNPLLVGNKRKEPDAQAVSSLFFDNELFGGVEYRNPGDSESEPEQDGDDDQDDENNKPIDISKLKKQKPQAAQPITKKQKTTNSAEFGKQKSKYQKNPTLDDKDDQDDDDDKGNSIKGFEEVPVQEEVEYESDSDEDIDDKIKTKALGEFLIRKKSRQDLIDDSFNKYAFNDTGLPNWFTDDENRHNKAQTPLTKEMVDEIRRKIKEIDDRPIKKIAEAKARKKYRLGKKMEKTRDKASSIVDNPEMSNREKSKAIEKLYSGTDKKNMKPKKIIMIAKKSKTAGGGTGKYKIVDKRMKKDLRAQKNKLKTVGRSKDSSKKSKPSGGKNKK",
    "output": "RNA 2'-O-methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK",
    "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAEQEFRHMVRITRKDVDGNSTIATALTEIRGIGKAFAIAICKVLDLDQDAQIGYIDDESVKQIEAVLENPQEFGIPEWFLNRRNDYETGETKHLIESDLNMTLRDDLNRMKMIRSYKGKRHEVGLPVRGQRTKSTFRHGSSVGVSRTRPTGN",
    "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKALDQLTFDNRFARLGDAFSTQVLPEPIADPRLVIASKSAMALLDLDPAQADTPVFAELFSGHKLWEGADPRAMVYSGHQFGSYNPRLGDGRGLLLAEVVNDAGEHWDLHLKGAGQTPYSRMGDGRAVLRSSIREFLASEALHALGIATSRALCVIGSSTPVWRETRESAAMLTRLAQSHVRFGHFEYFYYTKQPEQQRVLIDHVLEQHYPECREAEQPYLAMFRTIVERNAELIAHWQAYGFCHGVMNTDNMSILGITFDFGPYAFLDDFDANFICNHSDDRGRYSYANQVPIAHWNLSALAQALTTVIEVEPLKEALGLFLPLYQAHYLDLMRRRLGLTTAEDDDMALVERLLQRMQSGGVDYNLFFRRLGDQPVAEALKGVRDDFIDLAGFDAWGADYLARCEREAGNGDGRRERMHAVNPLYVLRNYLAQKAIEAAEAGDYSEVRRLHQVLSTPFEEQAGMQAYAERPPAWGKHLEISCSS",
    "output": "Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MANNEESRGLKSLFDWFANRRKAGATNPERQEREIADGLWHKCSKCGVLTYTKDLRANQMVCVECGHHNRVDSDERIRQLIDQNTWRPMDENLRATDPLQFRDRKAYSDRLREMEDKLGLLDAVKTGLGQINSSPVALAVMDFRFMGGSMGSVVGEKITRLIEQATQRRYPVVIICTSGGARMQEGMLSLMQMAKISAALERHRDARLLYIPVLTNPTTGGVTASFAMLGDIILAEPKATIGFAGRRVIEQTLREKLPDDFQTAEDLLKHGFVDDIVPRTQLKNTLSQLIALHQPVPTTPPMVLWETMSLSSTAVE",
    "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD",
    "output": "Catalyzes the exchange of L-carnitine for gamma-butyrobetaine . Can also transport D-carnitine and, with lower efficiency, acetyl-L-carnitine and glycine betaine ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSENLPQSPERAESPQAPRRKPRVAVVFGGRSSEHGISVVTAGAVMRAIDRTTYDVLPIGITTDGRWALTADEPERMAITDRKVPDVDRLTESAEGSVVLSVDPGSREVVYTEPGSVPKALGEVDVVFPVLHGPYGEDGTLQGLLELSGVPYVGAGVLASAVGQDKEYMKRVFLSFGLPVGPYEVVRPREWDNDPAAARERIVDFAGEHGWPLFIKPARGGSSMGITKVDSVEGLDAAIEEARRHDPKFLVESLLRGREIECGVLEFEDGPRASVPAEIPPVTSHDFYDFEAKYIDSAAGLVPAPLTEEQTAEVRRLAVAAFDAVSCEGLVRADFFLTEDGTFVINEINTLPGFTPISMYPRMWQESGVDYPELVDRLIQAALSRSTGLR",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLPRKREIVAGEVEDLQKKTRAGEGEATREEGDAAMAGRGNEIDEDLHSRQLAVYGRETMKPLFGSNVLVSGLQGLGAEIAKNLVLAGVKSVTLHDDGNVELWDLSSNFFLSENDVGQNRAQACVQKLQELNNAVLVSALTGDLTKEHLSKFQAVVFTDISLDKAIEFDDYCHSHQPPIAFIKSEVRGLFGSVFCDFGPEFTVLDVDGEEPHTGIVASISNDNPALVSCVDDERLEFQDGDLVVFSEVHGMTELNDGKPRKVKNARPYSFFLEEDTSSFGAYVRGGIVTQVKPPKVIKFKPLKEAMSEPGEFLMSDFSKFERPPLLHLAFQALDKFRTELSRFPVAGSTDDVQRVIEYAISINDTLGDRKLEEIDKKLLHHFASGSRAVLNPMAAMFGGIVGQEVVKACSGKFHPLYQFFYFDSVESLPVDPLEPGDLKPKNSRYDAQISVFGSTLQNKLEEAKIFMVGSGALGCEFLKNLALMGISCSQNGNLTVTDDDVIEKSNLSRQFLFRDWNIGQPKSTVAATAAMVINPKLHVEALQNRASPETENVFNDAFWENLDAVVNALDNVTARMYIDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWARSEFEGLLEKTPTEVNAFLSNPTTYISAARTAGDAQARDQLERVIECLDRDKCETFQDSITWARLKFEDYFSNRVKQLTFTFPEDSMTSSGAPFWSAPKRFPRPVEFSSSDPSQLSFILAAAILRAETFGIPISEWAKTPNKLAAEAVDKVIVPDFQPKQGVKIVTDEKATSLSSASVDDAAVIEELIAKLEEVSKTLPSGFHMNPIQFEKDDDTNFHMDVIAGFANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKALAGGHKVEDYRNTFANLAIPLFSIAEPVPPKTIKHQELSWTVWDRWTVTGNITLRELLEWLKEKGLNAYSISCGTSLLYNSMFPRHKERLDRKVVDVAREVAKMEVPSYRRHLDVVVACEDDDDNDVDIPLVSVYFR",
    "output": "Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTAVHKDNLTSEHFIVCALYKFVALPEFEALRKPLLDVMEANEVRGTLLIASEGINGTVSAKRAGIDNLLKWLEQQPSLNNIVTKESYDDECPFYRTKVKLKKEIVTMGVEGIDPLKVVGSYVKPNEWNALISDPEVILIDTRNDYEIEIGTFQNAVDPNTKTFREFPQWAKENLDPSKHKKVAMFCTGGIRCEKSTAYMKEQGFDEVYHLEGGILKYLEEVPKDETMWEGECFVFDNRVAVNHDLQKGSYDQCHACRMPITEDEKLKAEYMEGVSCHHCIDNVSDEQRERFAERQKQIELAQARGEGHIGNEAQAILQQRKEAKNAKKQAQRSK",
    "output": "Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIRQAIAKVVELRDLSEGEMIEVMNQIMSGECTPAQIGSFITALRMKGETIAEISGAARVMRERATPIRVGRNVLDIDRDDINLDQETILDVVGTGGDGTNTFNISTTVSFIVSACGVKVAKHGNRSVSSACGSADVLEKLGVNLDVTPEQVERCINEIGIGFLFAPALHGAMKHAIGPRREIGIRTIFNILGPLTNPANADCQVMGVYREELVAKMAGVLHHLGCKRGFVVHGRDGMDEITLTGETAAAEVSPEGVRLFTITPEEFGFSRCSMQALKGGDAVANAAIVRAVLGGEPGPRREIVLLNAGFALLAAGRCATVAAGIDLAAQAIDSGAALMQIEKLATLTN",
    "output": "Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQIIEGKLQLQGNEKIAILTSRFNHIITDRLKEGAMDCFKRHGGDEELLDLVLVPGAYELPLILDKLLESGKYDGVCVLGAIIRGGTPHFDYVSAEATKGIASAMLKYSMPVSFGVLTTDNIEQAIERAGSKAGNKGFEAMSTLIELLSLCQTLKD",
    "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEVLRRSSVFAAEVMEVFDRSPTDKELVSQAKALCRDYINSRLIRAGVSWSKPEHNTPVPGGKLAEVSAILLRLGDELEYIRPNVYRNIARQLNISLHSETVVTDAFLAVAAQIFTAGITWGKVVSLYAVAAGLAVDCVRHAQPAMVHTIVDCLGEFVRKTLVTWLKRRGGWADITKCVVSTDPSLRSHWLVAAVCSFGHFLKAIFFVLLPER",
    "output": "May play a role in apoptosis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVAQTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS",
    "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSILKKPDLTDPKLRAKLAKGMGHNYYGEPAWPNDLLYVFPVVILGTIACSIGLAILEPSSLGEKSNPFATPLEILPEWYFFPTFNLLRVIPNKLLGVLSMAAVPAGLLTVPFIENVNKFQNPFRRPIATTIFLISTVITIWLGIGATMPINNAITLGLF",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MELSRRDFMKANAAVAAAAAAGIVLPVKNVQADDSGIKWDKAPCRFCGTGCSVLVGTKDGRVVATQGDPDAEVNRGLNCIKGYFLSKIMYGADRVQTPLLRMKDGKFHKEGDFTPVSWDQAFSIMAEKVKATLKAKGGNAVGMFSSGQTTIFEGYAKVKLWKAGLRSNTIDPNARHCMASAAVAFLRTFGMDEPMGCYNDIEKTDGFVLWGSNMAEMHPILWSRISDRRLSDNNVKVVVMSTFEHRSFELADTPIIFKPHSDLAILNYIANYIIQNDKVNWDFVNKHTKFKRGETDIGYGLRPEHPLQKAAKNVKNAGKMHDSSFEEFKKIVEPYTLEKAHEISGVPKHQLEALAKMYADPAQKLVSFWTMGFNQHTRGVWVNHMIYNVHLLTGKISTPGCGPFSLTGQPSACGTAREVGTFVHRLPADMVVMNPKHVEICEKAWKLPKGTIPTVPGYAAVMQSRMLKDGKLNFLWQMCTNNMQGGPNINEEIFPGWRNPENFIVVSDPYPSVSAVAADLILPTCMWVEKEGAYGNAERRTQFWYQQVKGPAQSKSDLWQIVEFAKYFKAEEVWNEELMAQMPEYRGKTLYEILYLNGEVDKYQVPTNIPGYLNDEADDFGFYIQKGLFEEYAQFGRGHGHDLADFETYHQARGLRWPVVDGKETLWRYREGFDPYVKAGEDFRFYGYPDGKAIILGVPYESPAESPDEEYDLWLSTGRVLEHWHTGTMTRRVPELHRSFPNNLVWMHPSDAKKRGLRHGDKVKVITRRGEMISHLDTRGRNKCPEGLIFTTFFDAGQLANKLTLDATDPISGETDFKKCAAKVVKA",
    "output": "Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDSNPCQDVSGDTSSTPMANNNPTNDSTISSQNHSKIGLRKHQQQHYHQHSHSQMHSHSQQSPYINQLEYFTNNQFSRSFNSLILEDANDANTNNSSTTTLNKKTINKSPPFNIKQDLLNDSIDTFLDNSNTETIEDGDVTTTDDDHDFDDEDIEDPEAVQYTPTLNILKSKKVDSFDIISSKHRKSNSQITYNSHVRKPSEEDTSSSMATIRLSNNSQSSIKRSSKYLNLSIDSNLKTVDGGKIPDEIDDISLNEIDVAVAPNDFSSPLSARKPDIFAAITAANGNSNNQFKRPHKLVSQSPSPSSKNKFRISSSTTSSPQSNLHSPSKLGSKGFKMFKNANRDAIMSSSRVMTPEKPKMVSKIFGKSAKIRRAYTPTHTSTPMAVSSLNPPSSSTSNSTTAAITSTSPPANEHYDIDNDFDSPSKNRKSSNISASSIIIYQDENHIKSNHARKSSNPIPYPPTEPLPTNISASVAETGKGSTTTKSNLSKGCPLFDDKENKASYQFVKPLQTAFNSSGLVKKNSISGSSDRKLPPETPIKRNPLMILNTNKVVPPYSSGFAEGKDVMGDQHDIYSHIPCQNQRFPGSVNPNTTTNNNNTQQHHDSDLSIEVGRNNSYDASSSTINNTSYIKIFPSSELKKEQVLQRPQEDLELVFNSDIELDDNIIPETPTKKSLLPNQHHQHHLPLYTQSKSPLLKFDTEKDGRRNLSIVLDKSNATKREISEPPSTPINMSFAKNSFKKPMNNAERGDDPDSIIAQRIDIMPSLDEADSVSVYPSKIDEHLIEKFGMKNIKYIGSGAFSIAFECLFNNEKFAIKRTKKPLIGKLEKQTIKREIEALRVLTSIKEDEATNMQEQEEGKEYLVYFIEAWDFNNYYYIMTEFCEGGTLFDFLEENKHYKIDEFRIWKILIEILNGLKFIHSKNYLHLDLKPANIFITFEGSLKIGDFGLATKLPILEKDFDLEGDRNYIAPELINDKIYTPFADIFSLGLIILEIAANIILPDNGTPWRKLRSGDLSDAGRLSSDNISMFLQHNPNTNSNISGSGSRSGSGSTGGNGSAGDGSTNSTNFSYNSLSGNSLTLNPPVKAVHGTSDTNNTLASELSKNIEGLIPSWAPDFLVHGDSMNLDKLVNKMLRPNPFDRPSACNILEMPECLIVENRRKCGATIFEGEFGSPPDE",
    "output": "Protein kinase that acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylating and inhibiting the mitosis-promoting cyclin B-bound CDC28 at 'Tyr-18'. SWE1-mediated inhibition of CDC28 acts in a cell size or morphogenesis checkpoint to delay mitosis in response to defects in growth, actin organization or bud formation. Plays an important role in filamentous growth."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "CNQSTLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYKATKSVKTVRKCSNKIYFRNPMTENSKFFMKHGMRNGINSTMYQSPVRL",
    "output": "G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity. May play a role in the perception of pain. Plays a role in the regulation of behavior, including impulsive behavior. Required for normal proliferation of embryonic cardiac myocytes and normal heart development. Protects cardiomyocytes against apoptosis. Plays a role in the adaptation of pulmonary arteries to chronic hypoxia. Plays a role in vasoconstriction. Required for normal osteoblast function and proliferation, and for maintaining normal bone density. Required for normal proliferation of the interstitial cells of Cajal in the intestine (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTDLSDIRREYAKGGLRRADLPQNPMDLFELWMTQARDAELSDPTAMCVATVDEHGQPFQRIVLLKRFDDTGFVFFTNLGSRKAQQIAANNKVSLHFPWHPLERQVSVLGEAQALSTAEVLKYFMTRPKDSQIAAWVSQQSSKLSARQVLEGKFFEMKAKFAKGDVPLPSFWGGYLVRPSSIEFWQGGEHRLHDRFIYTRHDAEWEIDRLAP",
    "output": "Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "ASEDGGRGPYVQADLAYAYEHITHDYPKPTDPSKGKISTVSDYFRNIRTHSIHPRVSVGYDFGGWRIAADYARYRKWSDNKYSVSIKNMRVHKHNSNRKNLKTENQENGSFHAVSSLGLSAIYDFQINDKFKPYIGARVAYGHVRHSIDSTKKITGLLTTSTPGIMSGVYKVLRTPGAHRESDSIRRVGLGVIAGVGFDITPKLTLDAGYRYHNWGRLENTRFKTHEASLGVRYRF",
    "output": "Implicated in a number of adherence functions. OPA proteins are implicated in pathogenesis and are subject to phase variation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKLQVLVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEALTSRSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDASAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDDEDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEVD",
    "output": "Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAYSATQSKSGYQAGVKDYRLTYYTPDYTPKDTDVLACFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDLLTDLDRYKGRCYDIEPVPGEDNQYFCFVAYPLDLFEEGSVTNMLTSIVGNVFGFKALKALRLEDVRIPVAYLKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYEALRGGLDFTKDDENINSQPFQRWRDRYLFVMEAVHKAQAETGEIKGHYLNVTAPTCEEMFKRAEFAKELGAPIIMHDYLTAGFTANTSLAKWCRDNGILLHIHRAMHAVIDRQKNHGIHFRVLAKCLRMSGGDHLHSGTVVGKLEGDRAITMGFVDLMRENYVEADRSRGIFFTQDWASMPGVMPVASGGIHVWHMPALVEIFGDDSVLQFGGGTLGHPWGNAPGATANRVALEACIQARNEGRDLAREGNDIIREAAKWSPELAAACELWKEIKFEFKAVDTL",
    "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAGELNAAPVLSTPEDHLFEYAVVPTDDQTKAKSDDELRDIYEITRTAKEVGEGGWRRIGLQFPDHMLCDAPRVVQLLEAELASLPQPTVPTSTADLQSTATACPEPSTTNNGQCGRNVQQNGTGCGCGKQAPAPVESQPKARRVYVLADTSYSACCVDEIAAEHVNADVVVHYGRSCLSPTSRLPVIYVFTKHILDRDAALVKFEKEYPDKEAKVVLMADVTYQVHVPSLLSELQSGGYVNLLATEIVHNPMGRIPNRKVVDAQGKEVEISHGSETSTGLDLRDYSIFHISQPPTALLLALCSRVKNLYIFQTSSDSSSLYSAQRLLGRRYARLLSLTTAGIIGILVNTLSVSNYLSSIDSIRKQIAAAGKKSYTMVVGKLNPAKLANFAEIDGWVVVGCWESSLIEDDAGFYKPVITPFELELALASDDERVWTGEWWGGIEAVKPPIDEKPGEKKSEENENNEAQDTAGAEQASGDGELDSEEESAPPEFDWRTGKLVSHSRPMRMAASKPKSAKKEDSSDKPDAPPRSSALTLRSKAQELASVNGVVSPGAEYLRTQRTWVGLGTDFDEEASMTIEEGRGGVARGYTVGGEGEKHLMS",
    "output": "Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. Dph-1 and dph-2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph-3 and a NADH-dependent reductase, predominantly cbr-1 (By similarity). Facilitates the reduction of the catalytic iron-sulfur cluster found in the dph-1 subunit (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAAAGQAEECLPLPAAESSKTSLPTPPAVPAGKKPKKCLVYPHPPRSSRLSRSVLRWLQGLDLSFFPRNVTRDFSNGYLVAEIFCIYYPWDLRLSSFENGTSLKVKLDNWAQIEKFLAKKKFKLPKELIHGTIHCKAGVPEILIQEIYTLLTHQEIRSIQDDLANFTDYIYQMRLPLVPRNTVSKSIKNNIRLSELLSNPNVLSNELKIEFLILLQMLQRKLSRKLNPGWFDVKPTVGEITIDRLPAHSYKRRYKSRGSKEKAAQPLSKSDNDGNARKEIHVKQSGNPCENTENL",
    "output": "May play a role in apoptosis regulation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDELKKLAGVTAAKYVKNGMIVGLGTGSTAYFFVEEIGRRVKEEGLQVVGVTTSNRTTEQARGLGIPLKSADDIDVIDVTVDGADEVDPDFNGIKGGGGALLMEKIVATPTKEYIWVVDESKLVETLGAFKLPVEVVRYGSERLFRVFKSKGYCPSFRETEGDRFITDMGNYIIDLDLKKIEDPKQLANELDHTVGVVEHGLFNSMVNKVIVAGKNGLDILEK",
    "output": "Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTQAKDHAMNIGVFIPIGNNGWLLSENAPQYMPSFDLNKQITLKAEQHGLDFVLSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIKLYATAPTLCLPPAIVARMASTIDSISNGRFGLNLVTGWQRPEYAQMGLWPGDEYFGRRYEYLSEYAQVLRELWETGRSDLKGEFFQMEDCRLSPRPQAEMKIICAGQSAAGMAFTATYADYNFCFGKGVNTPTAFAPTVERLEEAKAKTGRDVSSYVLFMVISDETDEAARAKWEHYKAGADAEAIAWLGLQGAADTKSGADTNIRQMADPTSAVNINMGTLVGSHATVAALLDEVVTVPGTGGVLLVFDDFLKGLDDFGTKIQPLMRSRRHVTGEALAEVA",
    "output": "Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLFSFFRNLCRVLYRVRVTGDTKALKGERVLITPNHVSFIDGILLALFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVIFPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQITLHILPPTQVEMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFGAGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNGYLRVEKPGVLEVPTAENIRGEMERDWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPELAVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE",
    "output": "Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEEDRGSALAAESALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLIPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRLERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLSHKDVSFSEEEFQKHEGMSERERQVMKKLKEVVDKQRDEIRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGELNQNGEEEPVAELGGEECVSEAEKVAMDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEIEEENQIPQPPPIAHPRMSPQPESGIKRLFSFFSRDKKRLANTQRNVRIHETFGQWANCHRDDGYTEQGQEALQHL",
    "output": "Plays a role in the regulation of cell shape and polarity (By similarity). Plays a role in cellular protein transport, including protein transport away from primary cilia (By similarity). Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus (By similarity). Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution (By similarity). Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTYHIDIQNATGKLLPLSEDEITKLASLALRDHKQDAELTVRLVDVEEMTYLNHTYRKKNKPTNVLAFPCSLPANIELECPLLGDVVICPEVLLAESAQFNKSLHAHWSLILIHGVLHLLGYDHIKDEEASIMQMLEAKLLAELGYANPYEVEENELE",
    "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAQHTVYFPDAFLTQMREAMPSTPSFDDFLAACQRPLRRSIRVNTLKISVADFLRLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDIAAAPGSKTTQIAARMNNEGTILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRLGGTLVYSTCTLNREENEAVCLWLKETYPDAVEFLPLGDLFPGTNKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPTPKYKVGNFPFSPVKDREAGQIRQAAASVGLNWDENLRPWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIALASPDNENAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKLFTSNA",
    "output": "Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNLSSLKPAEGAVKSRKRIGRGPGSGLGGTSTRGHKGAKSRSGYSKKIGFEGGQMPIQRRLPKFGFKNINRVEYKPINLSVLQTLSEANSLSKISVEDLIAAGLVSRNSLVKILANGTVTTALTVEAHAFSKTAEEAIVRAGGSVVKL",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKDQIIEAIKEMTVLELNDLVKAIEEEFGVTAAAPVAVAGGAAEGGAAEQTEFDVVLESAGSSKIGVIKVVREITGLGLKEAKALVDGAPAPIKEGVAKEEAEEIKGKLEEAGASVELK",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTVLHSIDFFSSSSAPVAIEARAPQSAFPEHHHDFYEIVIVEEGAGVHVFNGNPYTLSRGCVCFVRDHDRHLFESTDDLFLTNVLFRAPDAFRFLSGVGHFLPRECDGVYPSHWRVNGQVLQQIKCLIACLEHAPKSDQVEDIALHESVFMQLLVKLWQGCQTQVGDDQEGRLYQLLDWLQNNYSEAVEWPELADRFALPLRTLHRQLKNKTGMTPQRYLTRLHLLQARHQLCYSDNSVTDIAYLCGFGDSNHFSTLFKREFSQSPRDLRSQL",
    "output": "Activates expression of the rhaBAD and rhaT operons."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSQSPIELKGSSFTLSVIHLHDSRPEVIRQALQEKVDQAPAFLKNAPVVINVATLPNGANWKDLQQAVTSAGLRIVGISGCQDERQKRAIARAGLPLLSEGKGQKMAPEPVVSPPENVPTKTRIINTPVRSGQQIYARNCDLIVISSVSAGAELIADGNIHIYGMMRGRALAGASGDAQCQIFCTHLGAELVSIAGQYWLSDQIPSDYFGQAARLHLLDNALTIQPLN",
    "output": "Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKDILKLSIAEMHENLIKKEFSAVELTQAHIDAINNEQLNAFITKTPEVALNAARKADHILTHEQDKITSLTGIPVGIKDLFCTKNIKTTACSNILRNFTPQYDSTVVKRLIDDGAVMLGKLNMDEFAMGSSNSNSCFGPVENPWTRADGVKVVPGGSSGGSSAAVAGFLCAGALGSDTGGSVRQPAAFCGIVGLKPTYGRCSRSGMIAFASSLDQAGVLTRTVKDAALMLQPICGYDTQDSTSANITTPRFLDSITNIIKGKRIGIPKEYELSNKYKEYEEVSEMWLKGIKYLENEGAEIVNISLPHTSYALPVYYIICSAEASSNLARYDGIKYGTRVNSDNINEMYELTRGNNLGTEVKRRILIGAYALSSGYYDAYYNKAQCIRRLVTNDFVESFKSVDYILTPTAPKEAFAMDEQLDTLTMYLNDVFTVPASLAGLPAISIPIGLSKNKLPLSLQIIGNYYDEGGILNIASVIEKYTGNILK",
    "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKFVEIRDLQVTYMGKDKPSIVVDKLDIEEGESVLITGRSGSGKSTLVSVINGVIPHLINAEIKGEVRVFGFDVKSTPIHEISKYVGTLLQDPDTQAFNYTIIDEVAFGVENYMISRDEMIERVEESMKIYGISHLRDREINTLSGGELQRTILASVLAMRPKALILDEPTSNIDPQGTREILELVKTFRSEGISLVLVEHKIERVLPFVDRIIVVEEGKIAVDVRKDEIVDKADFLYSLGLEIPDYMLFLKKNGFRKIDYEYLRKTYTYRPPSRIGGKGEALYASVKVKTKNGIYLINTKISLKQGTITALMGKNGSGKTTLLKVIVGLIDKKRLIVEEEKVIVNGVDLSKTKLVERGKFIAYLPQFFDVMFIKRTVEDEIKFSMKNRGTYDEKRLGEVLKMFSLDAYRKEDPLVLSMGQRRRVAMASVLAGGAKVILMDEPTSGQDWYHRQILGKELLELRDKGYTILVVTHDSRFVDRFADYLLVMNEGKIVLEGKPEEVFIKSLRHGIEPPLEYELGGLIKNEHFS",
    "output": "Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAVDHDDFLHLSKPLAPSAVGFNANVAPLTVTIQPQAILSILDHAVRRDIRDTQATRVIGALVGVRSEDGTDVEVRSTFAIPHTENEDQVEVDVEYQKNMLALTLKASPRESLLGWYTTSHELNSFSALIQNFFASPETGTFPHPAVHLTMSTDPGADIEPRCYISAPAAVSPDRAAESCFFIQVPHRTPPTNESDRAALEAIAAGKDDEARTAPVLSDVEALARSLEQTIDMLDRTSEYVGAVLDEEREPSHALGQYLMNNLSLAPKVDSVSIEHDFNNHIQDVLMVSYLTNTIRTQVDLAQRLALANLTDKDEKKEGEDGKAERGGGGRGGRGGKRGGGRGGGQQREPREPREPRESREPREPRESGE",
    "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVNIRPDEISNIIRKQIEQYNQEVKVINIGTVLQVGDGIARIYGLDKVMAGELVEFEDGTVGIALNLESDNVGVVLMGDGLSIQEGSSVEATGKIAQIPVSDAYLGRVVNALAQPIDGKGQIPAYEFRLIESPAPGIISRRSVYEPMQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQNVICVYVAIGQKASSVAQVVNTFEERGALEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRKQHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSQLGEGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQSQSAPLAVEEQVATIYTGVNGYLDVLEVEQVKKFLVQLREYLITNKPQFVEIIRSTKVFTEQAEIILKEAIKEHTEFFLLQEQK",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGINMLDELKEDLVGIDIRFDEPLKRYTYTKVGGPADYLAFPRNRYELFRIVKFANKHNIPWMVLGNASNLIVRDGGIRGFVIMFDKLNGIAVNGYQVEAEAGANLIATTKVACFHSLTGFEFAAGIPGSIGGAVFMNAGAYGGEIAHILVSAQVLTKDGDIRTIDARDMRFGYRRSVLQETGEVVISAKFNLKPGDYEQIKHEMNRLNHLRELKQPLEYPSCGSVFKRPPGHFAGQLIMEANLEGHRIGGVEVSTKHAGFMVNVDQGTAKDYEDLIADVIAKVKENSGVTLEPEVRIIGDKLN",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSSLDSPRSKRCGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAPGKKRDMSSDLERDHRPHVSMPQNAN",
    "output": "Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDIKHIEVPVEYIAGKVVSKDYVDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVVDGVVTDEIHYLSAIEEGNYVIAQANSNLDDEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDDEVLRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNLVTRPGRVGIMGGTFDPIHYGHLVTAEAARWEFALQKVIFVPSGRPPHKKDYPVTDAEYRYQMTLLATASNPYFEVSRSEIDREGFSYTVDTVAEFRREYGPEVQLYFITGADAILEILTWKDVDTLLRECHFIAATRPGFQLNRLEESRPQLPVEGRHRIHLIEVPALAISSTDIRWRVKNNKPIKYLLPEAVEEYIRSRGLYRPRLDGVYEKG",
    "output": "Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTSVRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEYLIRTAIDPDAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTTSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKILATVDVLQSLAVVAETNHYIRPQFNDNHVITIQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIMSVPPQVESSSAVRQGQLSLFGDEEKAHEIRQALEAIDVMNMTPLQAMTTLYELKKLL",
    "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPELVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSGIDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGRFTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVISAAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWVAAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN",
    "output": "Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGFSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNDTILPRMKSGERVIIAAHGNSLRALVKYLDNMSEDEILELNIPTGVPLVYEFDENFKPIKHYYLGNADEIAAKAAAVANQGKAK",
    "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE",
    "output": "One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIRVLVIDDSLFIRTVVQDMLSDDPDIQIVGVASDGLEALDKIRELKPDLITLDIEMPRLDGLSMLERKKEIDRFPKTLVLSSLTSEGAEMTKRAIALGADDFMLKPRGIKNIREIGGELKHKIKNICTIAYITAKPVLKDSNARNVVLIGSSAGGPPMLDTIVSKLPSDLNAAVIITQHMPKGGFTAALAARLNRISPLQIRETENGDVLKNGTVLVSRAGFHTIISSVLDKGGSQSGKIILTDSPPVHNVKPAVDKTFISAAQVFGNHCVTAILSGMGNDGGEGTEAIKKAGGVTIVCREEDCLVYGMARSALSRNCVDHVLSLQAIPEKIVETIRAMNG",
    "output": "Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKLNRAIGVIDSGVGGLTVAKELIRQLPKERIIYLGDTARCPYGPRSREEVRQFTWEMTEHLLDLNIKMLVIACNTATAVVLEEMQKQLPIPVVGVIHPGSRTALKVTNTYHVGIIGTIGTVKSGAYEEALKSINNRVMVESLACPPFVELVESGNFESEMAYEVVRETLQPLKSTDIDTLILGCTHYPILGPVIKKVMGDKVQLISSGDETAREVSTILYHSKMLNEGEEQSDHLFLTTGKIGLFKEIASKWFGQPIENVKHIHLEKE",
    "output": "Provides the (R)-glutamate required for cell wall biosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAEHSAPVLEIDPKYGPFDKHTPMMQQYLRLKSGHPNTLVFYRMGDFYELFFEDAEKASRLLDITLTARGSSNGHPIRMAGIPFHAAEQYLAKLVKLGESVAICEQIGDPATAKGPVERKVVRVVTPGTLTDAALLSDKINNHLLAIAHLPAKRGAAPLIGLAWLNLVGGELRVMECSPDQLDRELERIRPAEVLADDATLNTIQVDVARTRLPDWHFDVEAGTRRLREQLGVASLVAFGAETLTAALAAAGALLNYAAATQGQSLRHVIGLTVEHESEFIGLDTATRRNLELTETLRGQESPTLFSLLDTCATSMGSRLLRHWLHHPLRDRAIPQARQQAIEVLLGGDWQTLRSTLRTLSDVERITGRLALLSARPRDLSSLRDTLARLPEIREELPQSDAAPLLIELYAALTLPEDAHALLQRAVMAEPAAMVRDGGVIARGYDADLDELRDISENCGQFLVDLEARERERTGIANLRVEYNRVHGFYIEVTNGQAAKVPDDYRRRQTLKNAERYITPELKAFEDKALSAQDRALSREKLLYEELLQKLLPHLAEFKRIAAALAQADVLATLAERAHALSWSRPTLTDAPGIELTRARHPVVEQQVEQFVANDCMLQEARKLLLITGPNMGGKSTFMRQTALVVLLAYVGAFVPAEAAVIGPIDRIFTRIGAADDLAGGRSTFMVEMTEAAAILHRATPNSLVLMDEIGRGTSTFDGLALAWAIARHLLSHNRSHTLFATHYFELTQLPQEFAQAANVHLSAVEHGDGIVFLHAVQEGPASQSYGLQVAQLAGVPQPVIRAARKRLAWLEQHSADTGATPQLDLFALAADMPIVDEGDADAETPDSALADALAGIDPDDMTPREALDALYRLKALASPAA",
    "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKVIGIDLGTTNSCVAVMEGGEPIVIANPEGNRTTPSVVAFSKTGERMTGQVAKRQAITNPERTIISIKRDMGTDHKVDIDGKKFSPQEISSMILQKLKSDAEAYLGETVTQAVITVPAYFSDAQRQATKDSGKIAGLEVLRIINEPTAAALAYGLDKEHDQKIMVYDLGGGTFDVSILEIGDGVFEVLATNGNNKLGGDDFDQRIIDFLVDTFKKESGIDLKNDKMAMQRLKEAAEKAKVELSGVTSSNINLPFITADASGPKHLDVTLTRAKFDEITADLVENTMVPTRQAMQDAGLTPDKIDKILLVGGSTRIPAVQEAVKKYLGKDPFKGINPDECVAVGAAIQAGVLTGDVTGLLLLDVTPLSLGLETLGGVFTKLIERNTTIPTKKSQVFSTAADGQTSVEIHVLQGEREMAQYNKSLGRFQLTGIPSAPRGVPQIEVTFDIDANGIVHVSAKDLGTGNEQKITITASTNLSDSDIDKAVKEAEKFAAEDKQRKEEIDVRNNADSLIYQSEKSLKDLGDKVSADDKSKIESGVNKVKDALKGTDIEVIKKATEELQQSFYDISSKIYQQTQGAQSDPGAAGFGGQQEAPGAGQDENVVDADYKVVDDDK",
    "output": "Acts as a chaperone."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSWQQRVDDALTARRATDTLRRRYVVSQGAGRWLVANGRQYLNFSSNDYLGLSQHPQIIRAWQQAAIRFGVGSGGSGHISGYSVAHQALEEELAQWLGYPRALLFISGFAANQAVITALMKKNDRIVADRLSHASLLEAANLSPAQLRRFIHNDTQHLSRLLQSPCVGQQLVVTEGVYSMDGDSAPLAEIQHIARRHHAWLLVDDAHGIGVTGDEGRGTCWQRGVKPELLVVTFGKGFGVSGAAVLCSESVADYLLQFARHLVYSTSMPPAQAQALSASLAVIRSDEGRERREKLAALVQRFRAGVNASRFTLLNAHSAIQPLIVGDNSRALRLAEALRQQGCWATAIRPPTVPVGTARLRLTLTQAHEACDIDRLLEVLHGAGE",
    "output": "Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFDQLESIVGRYEELGELLSDPEVVSDTKRFMELSREEADLRDKVATYNEYKKVLETISDSEEMLGEGGLDDEMKEMLKEELSSAKSQKEVLEEEIKILLLPKDPNDGKNIILEIRGAAGGDEAALFAGDLLNMYQHFSESQGWKFEIMEANITGIGGYKEVSALISGPSVYSKLKYESGAHRVQRVPVTETQGRVHTSTATVLVMPEVEEFEMTIEQKDLRVDIYHASGAGGQNVNKVATAVRMVHLPTGIKVEMQEERTQQKNRDKAIKLLNTKVFDYYQQIELDKQNAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDSILSGKMDEVIDALIVYDQTKKLEELNK",
    "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFQNNPLLTQLKKNLHAKSPRVEGIVKSTERGFGFLEVDPQKSYFIPPKNMKNVMHGDKIIALLTTEKDREIVEPEKLIEPFLNRFVGKIEKKDNRLFIVPDYPFLKDLITCQPNKNCINIFQNGDWAVAQLKKHKLKGDHLFYAELTEKITQEDDPLIPWWVTLARHDLDRKEPLAEDDDLILKESDNRKDLTDLDFITIDNTNTKDIDDALFVSEKNNGDISLIVAIADPTAYIKHGSKLDVIASKRIFTNYLPGFNIPMLPRNLSEDICSLNPNKRRPVLACHITVLKNGNISNKIEFFLAWIKSKSKLSYDHVSDWIEKIGSWIPPTKSIANQILILHRLCLLRIKWRKKNAVLFKDSIEYRFHVSEHGKIIDVLIEKRRIAHKIIEESMIVANISAANFLSKNIGFGIYNVHSGFDLVNAENAVSFLRSYNLNFTVKEITTLKGFCNLRRVLNIISNNYIDSRIRRFQSFGDFSTIPGPHFALGFSEYATWTSPIRKYSDMINHRLLKSIIKKEKSIKPGEDIKIKISEQRRRNRMAERDVLDWLYTIFLQKKKYQNQKFNAEITDISRSGIRARLIENGANVFIPGTLIHPIREELNFNQESGKVFINGIMHYKISDLIQVTLSDIRLKTRSIIAKPVFEKFK",
    "output": "Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLKPPLPLRSLLFLQLPLLGVGLNPKFLTPSGNEDIGGKPGTGGDFFLTSTPAGTLDVSTLPLPKVQCFVFNVEYMNCTWNSSSEPQPNNLTLHYGYRNFNGDDKLQECGHYLFSEGITSGCWFGKKEIRLYETFVVQLQDPREHRKQPKQMLKLQDLVIPWAPENLTLRNLSEFQLELSWSNRYLDHCLEHLVQYRSDRDRSWTEQSVDHRHSFSLPSVDAQKLYTFRVRSRYNPLCGSAQHWSDWSYPIHWGSNTSKENIENPENPSLFALEAVLIPLGSMGLIVSLICVYCWLERTMPRIPTLKNLEDLVTEYQGNFSAWSGVSKGLAESLQPDYSERLCHVSEIPPKGGEGPGGSPCSQHSPYWAPPCYTLKPEP",
    "output": "Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKILEDRIRQDGTVLTGNVLKVDNFLNHQVDPQLMNELGQEFARRFQDAHITKILTVESSGIAPAVMAGLHLNVPVIFARKHKSLTLTDNLYTAKVYSYTKQVTNEISIDRRFLAADDRVLIIDDFLANGQAVQGLLDIAKTAQITVAGVGVVIEKRFQKGHQMVTDAGIQLEALASIASFEAGQVIFAQD",
    "output": "Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQISQAGINLIKSFEGLQLKAYKAVPTEKHYTIGYGHYGSDVSPRQVITAKQAEDMLRDDVQAFVDGVNKALKVSVTQNQFDALVSFAYNVGLGAFRSSSLLEYLNEGRTALAAAEFPKWNKSGGKVYQGLINRRAQEQALFNSGTPKNVSRGTSSTKTTPKYKVKSGDNLTKIAKKHNTTVATLLKLNPSIKDPNMIRVGQTINVTGSGGKTHKVKSGDTLSKIAVDNKTTVSRLMSLNPEITNPNHIKVGQTIRLS",
    "output": "Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPREQGVRVVARNRRATHDYTIGDTWEAGLVLQGTEVKSLRAGKATLTDAFAQVDERGEVWMYNLHIPEYAFGTWRNHDVMRKRKLLLNKREIAKLSREADGPGKTIVPLQLYFKDGYAKVEIAVGTGKRDWDKRQAIRERDAKREAQRALANRVRNRKR",
    "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "VDLTAEEKAAVLALWGKVNEDEVGGEALGRLLVVYPWTQRFFDSFGDLSTPAAVLGNAKVKAHGKKVLHSFGDGVHNLDNLKGTYAALSELHCDKLHVDPENFRLLGNVLVVVLAQHFGQEFTPELQAAYQKVVAGVANALAHKYH",
    "output": "Involved in oxygen transport from the lung to the various peripheral tissues."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKRRKTALMMLSVLMVLAIFLSACSGSKSSNSSAKKSAGKPQQGGDLVVGSIGEPTLFNSLYSTDDASTDIENMLYSFLTKTDEKLNVKLSLAESIKELDGGLAYDVKIKKGVKFHDGKELTADDVVFTYSVPLSKDYKGERGSTYEMLKSVEKKGDYEVLFKLKYKDGNFYNNALDSTAILPKHILGNVPIADLEENEFNRKKPIGSGPFKFKEWKQGQYIKLEANDDYFEGRPYLDTVTYKVIPDANAAVAQLQAGDINFFNVPATDYKTAEKFNNLKIVTDLALSYVYIGWNEKNELFKDKKVRQALTTALDRESIVSQVLDGDGEVAYIPESPLSWNYPKDIDVPKFEYNEKKAKQMLAEAGWKDTNGDGILDKDGKKFSFTLKTNQGNKVREDIAVVVQEQLKKIGIEVKTQIVEWSALVEQMNPPNWDFDAMVMGWSLSTFPDQYDIFHSSQIKKGLNYVWYKNAEADKLMKDAKSISDRKQYSKEYEQIYQKIAEDQPYTFLYYPNNHMAMPENLEGYKYHPKRDLYNIEKWWLAK",
    "output": "This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence. AppA can bind and transport tetra- and pentapeptides but not tripeptides."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIWTRLPLYGPSKPSTGGWQPLRFDGGAFHVKGTAELARALLVLRLCAWPPLVTHGLAFQAWSQRLLGSRLSGALLRASIYGQFVAGETAEEVRNCVGQLQALGLQPLLAVPTEEEPDSTAKTSEVWYEENLSAMLRCVDLSRALVDAHGPARNSLMQLKVTALASTRLCKELSAWIQRPRGSSELSPERLAEAMDSGRNLQLSCLSTEQNQHLQASLSRLHRVAQHARAKCVRLLVDAEYTFINPALSLLVAALAVRWNSPEEGGPWVWNTYQAYLKDTHQRLEQDAEAAHKAGLAFGVKLVRGAYLDKERSMTQLQGKEDCTQPDYEATSRSYSRCLELMLRCVSNHGPPCHLMVASHNEESVRQATKRMWELGIPLDGPVCFGQLLGMCDHVSLALGQAGYMVYKSIPYGCLEEVIPYLIRRAQENRSVLQGARREQALLSQELWRRLLGRTA",
    "output": "Dehydrogenase that converts trans-4-L-hydroxyproline to delta-1-pyrroline-3-hydroxy-5-carboxylate (Hyp) using ubiquinone-10 as the terminal electron acceptor. Can also use proline as a substrate but with a very much lower efficiency. Does not react with other diastereomers of Hyp: trans-4-D-hydroxyproline and cis-4-L-hydroxyproline. Ubiquininone analogs such as menadione, duroquinone and ubiquinone-1 react more efficiently than oxygen as the terminal electron acceptor during catalysis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKILISDNISLELFCKNPIKILEKSNKGIIGVLKNKSPIFYVITPYILKKIFDLECNLLDLDKTKQQISKKFSMHPQWTPDKDFIRQAALWGITLTEEILESELASFISYWQAEGCFFHHIQWQQKLARSLQKSRSISYMSQKKRDITYIPTPDQTVPNGFRGK",
    "output": "This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKLTTFAPEFAEALPILEQIEAAGFEAYFVGGSVRDNLLGLPIHDVDIATSAYPAEIKQIFKRTVDTGIQHGTVMILDHGNGYEVTTFRTETGYQDFRRPDSVTFVRSLEEDLKRRDFTINALAMRADGEIIDLFDGIADLKAHKIRAVGVADERFHEDALRMMRAVRFESQLGFSVTETTQAAIEKHAALLEKIAIERIHVEFMKLMQGIERQNGLRTFIDTGLYRYCPDLADQLLALERLTALPTEQLHDESAVWLVVTYLLGQTPAQAGRFLKHWKSANDVIDAVKAGLVLLPKLLTATADQWDLYQAGQAVLVISLQIAQMVTTATIPTADWLERYDRLQIKQKADLAINGQILMQNGFQPGPILGKALAILERKVVLDELPNTTEALLKAAK",
    "output": "Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSNGAFDAIFEYAWGQIDKPISGDFIYGKDLPKLIEIIENIFQKAQKSGSYELRLPLFSEINKDLFRTFSNTKTFFKIHKEEFDDIFFNLVNHPLREILENAFIGVDSIPSDFIVSMNLNSPSKFLVENKNKNTEGAGISTPRKKLTESPIKLLSRXNIGKALEVQVEELKRELTAKQSLLQENERQVSELKIRLETYQEKYASIQQRFSDLQKARQVEDNQNSSRTSDPGSPLVTGIDQKAILEEFRRRLQRQTDTISFLKDQIRRERGLNCSNDKVSHSKRKHATTDGDGTFKNFISAVPSNIWVKATIRIIVCFALLAGVLPYIRKYVYAHDTPSQNSRLQLSWWENSGILSKIVWFFEDQTDLETEYRSNANVDDAYSRVFGI",
    "output": "Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNLIYNFSAGPAMIPRDVLNQAKKELHNWKNLGSSIMEISHRSEEFIQMALEAEKDLRDLLKIPDSFKVLFCQGGARGQFSAIPMNLLNNLQTADYINSGYWSNSAFMEAKKYCTPRSIFIRETNGVKESLLPMHKWNINENSAYIHYCPNETIDGLSIYEEPVFENKIIVGDFSSFILSRSINIKNYDLIYAGAQKNIGPAGITIIIIRKNIIGSSSKMTPSILDYKKISDHHSMFNTPPTFAWYLSGLVFKWLKKQGGLKAIEKLNKKKSDLLYKKIDNSDFYINKINSKHRSQMNVVFHLVNPKLNYIFLKEASKTGLNYLRGHSIVGGMRASLYNAMPLEGVESLVKFMSYFEKRYG",
    "output": "Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MANEFLFTSESVSEGHPDKVADQISDGVLDAILAEDPKARVACETLVSTGLVVISGEITTSAHPNYREIAQDVVRRIGYDNSDIGFDYKSCAVLAAINRQSSDIAQGVNEGEGLDLDQGAGDQGLMFGYATNETPSLMPLPIYYAHRIMQRQAEVRKDGRLPWLRPDAKSQLTVKYVDGKPVAIDTVVVSTQHNPEVSHAQISEAVIEEIIKPVLPKELMQGEVRYLINPTGRFVIGGPHGDCGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSAAYAGRYVAKNVVAAGLADKCEVQVAYAIGVAKPVSLMVNTFGTGKIADDKIVDLIRAHFDLRPKAIIQTLDLLRPIYSRTAAYGHFGRDEPEFTWEQTDKASALRAAAGL",
    "output": "Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLTLDQARSKMLEQLPFPTQTEYLNLQEAANRICAEDIISPINVPSFDNSAMDGYAVRLSDLQQSLTLSVAGKSFAGNPFQEEWPSKSAVRIMTGAMIPEGTDAVIMQEQVTLNEDGTITFSELPKPNQNIRRIGEDVKKGDVVLEQGAQLTPVSLPLLASLGIAEVKCYRQLKVGVLSTGDELVEVGKPLQSGQIYDTNRFTVKLLLEKLHCEVIDLGLLPDNEAEFEKAFIAAQSQADLVITSGGVSVGEADFTKAVLEKVGQVNFWKIAIKPGKPFAFGKLENAWFCGLPGNPVSALVTFYQLVQPLIAKLQGQKQWKKPPHFSAIATMNLKKAVGRLDFQRGFYYINEQGQIEVQSVGFQGSHLFSAFVKSNCFIVLEQERGNVSAGETVTIEPFNHLLG",
    "output": "Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASRAPLELLPLNRSQLSPPNATTCDDAPEAWDLLHRVLPSVIIIICVCGLLGNLLVLAVLLRPRRRLNVAEMYLANLAASDLVFVLGLPFWAANISNQFRWPFGGLLCRLVNGVIKANLFISIFLVVAISRDRYRALVHPMATRRRRQARATCVLIWVAGSLLSVPTFLFRSIEAVPELNNDSACVLLHPPGAWHVARMVELNVLGFLLPLAAIVFFNCHILASLRGRPEVRGARCGGPPDGRTTALILTFVAAFLVCWTPYHFFAFLEFLTQVQVVRGCFWENFKDLGLQYASFFAFINSCLNPVIYVFVGRLFRTRVWDLFKQCAPRRPPAVSWSHRKRVLQLFWQN",
    "output": "This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKMIKVKVIGRNIEKEIEWREGMKVRDILRAVGFNTESAIAKVNGKVVLEDDEVKDGDFVEVIPVVSGG",
    "output": "Functions as a protein modifier covalently attached to lysine residues of substrate proteins, as well as a sulfur carrier in tRNA thiolation. The protein modification process is termed sampylation and involves the formation of an isopeptide bond between the SAMP2 C-terminal glycine carboxylate and the epsilon-amino group of lysine residues on target proteins. Is able to form polymeric chains with itself likely at Lys-55, similar to ubiquitin and other ubiquitin-like proteins. May serve as a proteolytic signal in the cell to target proteins for degradation by proteasomes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQYRDLRDFIRELEKRGELKRIQTPVSPILEMTEICDRTLRKGGPALLFEKPTGFDVPVLGNLFGTPKRVALGMGAEDVAELREIGKLLAFLKEPEPPKGLKDAWSKLPIFKKVISMAPKVVKDAPCHEVIEEGEDVDLNRLPIQHCWPGDVAPLITWGLTITKGPNKERQNLGIYRQQVIGRNKVIMRWLSHRGGALDYREWCQKYPDKPYPVCVALGADPATILGAVTPVPDTLSEYAFAGLLRGHRTELIKAVGSDLQVPASAEIVLEGVIHPGETAPEGPYGDHTGYYNEVDTFPVFTVERITRRREPIYHSTYTGRPPDEPAILGVALNEVFVPILQKQFPEITDFYLPPEGCSYRMAVVTMKKQYPGHAKRVMLGVWSFLRQFMYTKFVIVTDDDINARDWNDVIWAITTRMDPKRDTVMIDNTPIDYLDFASPISGLGSKMGLDATHKWPGETSREWGRAIEKDPAVVARVDALWGELGID",
    "output": "Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTDIIRSDAATLAAKIAIKEVSSTEITRACLDQIEATDETYHAFLHVAADEALAAAAAVDKQVAAGEPLPSALAGVPLALKDVFTTSDMPTTCGSKILEGWRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAYGPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTATVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDSTSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEAAVEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRVGDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKVRTLIARDLDAAYRSVDVLVSPTTPTTAFRLGEKVDDPLAMYLFDLCTLPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPLLSAI",
    "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "RLVLEVXASVEADV",
    "output": "Has kinin-like biological properties. Causes contraction of isolated guinea pig ileum and relaxation of rat duodenum. Has a number of hypotensive properties: decreases arterial blood pressure and increases capillary permeability. Induces edema when injected into hindpaw of rat. May target bradykinin receptors (BDKRB). Does not lyse unfibrinolysed blood."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMTVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR",
    "output": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPKCPIPIRISFFSYFLKESRILSSNPVNFSIHLRFSSSVSVSPNPSMEVVENPLEAPISEKMFKSAPKMGSFKLGDSTLSSMIESYANSGDFDSVEKLLSRIRLENRVIIERSFIVVFRAYGKAHLPDKAVDLFHRMVDEFRCKRSVKSFNSVLNVIINEGLYHRGLEFYDYVVNSNMNMNISPNGLSFNLVIKALCKLRFVDRAIEVFRGMPERKCLPDGYTYCTLMDGLCKEERIDEAVLLLDEMQSEGCSPSPVIYNVLIDGLCKKGDLTRVTKLVDNMFLKGCVPNEVTYNTLIHGLCLKGKLDKAVSLLERMVSSKCIPNDVTYGTLINGLVKQRRATDAVRLLSSMEERGYHLNQHIYSVLISGLFKEGKAEEAMSLWRKMAEKGCKPNIVVYSVLVDGLCREGKPNEAKEILNRMIASGCLPNAYTYSSLMKGFFKTGLCEEAVQVWKEMDKTGCSRNKFCYSVLIDGLCGVGRVKEAMMVWSKMLTIGIKPDTVAYSSIIKGLCGIGSMDAALKLYHEMLCQEEPKSQPDVVTYNILLDGLCMQKDISRAVDLLNSMLDRGCDPDVITCNTFLNTLSEKSNSCDKGRSFLEELVVRLLKRQRVSGACTIVEVMLGKYLAPKTSTWAMIVREICKPKKINAAIDKCWRNLCT",
    "output": "May play a role in embryogenesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MWERLNCAAEDFYSRLLQKFNEEKKGIRKDPFLYEADVQVQLISKGQPNPLKNILNENDIVFIVEKVPLEKEETSHIEELQSEETAISDFSTGENVGPLALPVGKARQLIGLYTMAHNPNMTHLKINLPVTALPPLWVRCDSSDPEGTCWLGAELITTNNSITGIVLYVVSCKADKNYSVNLENLKNLHKKRHHLSTVTSKGFAQYELFKSSALDDTITASQTAIALDISWSPADEILQIPPLSSTATLNIKVESGEPRGPLNHLYRELKFLLVLADGLRTGVTEWLEPLEAKSAVELVQEFLNDLNKLDGFGDSTKKDTEVETLKHDTAAVDRSVKRLFKVRSDLDFAEQLWCKMSSSVISYQDLVKCFTLIIQSLQRGDIQPWLHSGSNSLLSKLIHQSYHGTMDTVSLSGTIPVQMLLEIGLDKLKKDYISFFIGQELASLNHLEYFIAPSVDIQEQVYRVQKLHHILEILVSCMPFIKSQHELLFSLTQICIKYYKQNPLDEQHIFQLPVRPTAVKNLYQSEKPQKWRVEIYSGQKKIKTVWQLSDSSPIDHLNFHKPDFSELTLNGSLEERIFFTNMVTCSQVHFK",
    "output": "Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKVTQASCHQGDIARFGARAGNQCVCNGIMFLHALHLGGTSAVLQTEALDAIMEEGARLDARLERELQKKLPAGGRLPVYRLGDEVPRRLESRFGRTVHALSRPFNGTTETCDLDGYMCPGIFDFLRYAHAKPRPTYVLVTVNSLARAVVFTEDHMLVFDPHSSAECHNAAVYHCEGLHQVLMVLTGFGVQLSPAFYYEALFLYMLDVATVPEAEIAARLVSTYRDRDIDLTGVVRESADTAATTTTAAPSLPPLPDPIVDPGCPPGVAPSIPVYDPSSSPKKTPEKRRKDLSGSKHGGKKKPPSTTSKTLATASSSPSAIAAASSSSAVPPSYSCGEGALPALGRYQQLVDEVEQELKALTLPPLPANTSAWTLHAAGTESGANAATATAPSFDEAFLTDRLQQLIIHAVNQRSCLRRPCGPQSAAQQAVRAYLGLSKKLDAFLLNWLHHGLDLQRMHDYLSHKTTKGTYSTLDRALLEKMQVVFDPYGRQHGPALIAWVEEMLRYVESKPTNELSQRLQRFVTKRPMPVSDSFVCLRPVDFQRLTQVIEQRRRVLQRQREEYHGVYEHLAGLITSIDIHDLDASDLNRREILKALQPLDDNAKQELFRLGNAKMLELQMDLDRLSTQLLTRVHNHILNGFLPVEDLKQMERVVEQVLRLFYDLRDLKLCDGSYEEGFVVIREQLSYLMTGTVRDNVPLLQEILQLRHAYQQATQQNEGRLTQIHDLLHVIETLVRDPGSRGSALTLALVQEQLAQLEALGGLQLPEVQQRLQNAQLALSRLYEEEEETQRFLDGLSYDDPPNEQTIKRHPQLREMLRRDEQTRLRLINAVLSMFHTLVMRLARDESPRPTFFDAVSLLLQQLPPDSHEREDLRAANATYAQMVKKLEQIEKAGTGASEKRFQALRELVYFFRNHEYFFQHMVGRLGVGPQVTELYERYQHEMEEQHLERLEREWQEEAGKLTVTSVEDVQRVLARAPSHRVMHQMQQTLTTKMQDFLDKEKRKQEEQQRQLLDGYQKKVQQDLQRVVDAVKGEMLSTIPHQPLEATLELLLGLDQRAQPLLDKFNQDLLSALQQLSKKLDGRINECLHGVLTGDVERRCHPHREAAMQTQASLNHLDQILGPQLLIHETQQALQHAVHQAQFIEKCQQGDPTTAITGSEFEGDFARYRSSQQKMEEQLQETRQQMTETSERLDRSLRQDPGSSSVTRVPEKPFKGQELAGRITPPPADFQQPVFKTLLDQQADAARKALSDEADLLNQKVQTQLRQRDEQLSTAQNLWTDLVTRHKMSGGLDVTTPDAKALMEKPLETLRELLGKATQQLPYLSAERTVRWMLAFLEEALAQITADPTHPHHGSRTHYRNLQQQAVESAVTLAHQIEQNAACENFIAQHQEATANGASTPRVDMVQAVEAVWQRLEPGRVAGGAARHQKVQELLQRLGQTLGDLELQETLATEYFALLHGIQTFSYGLDFRSQLEKIRDLRTRFAELAKRRGTRLSNEGVLPNPRKPQATTSLGAFTRGLNALERHVQLGHQYLLNKLNGSSLVYRLEDIPSVLPATHETDPALIMRDRLRRLCFARHHDTFLEVVDVFGMRQIVTQAGEPIHLVTDYGNVAFKYLALRDDGRPLAWRRRCSGGGLKNVVTTRYKAITVAVAVCQTLRTFWPQISQYDLRPYLTQHQSHTHPAETHTLHNLKLFCYLVSTAWHQRIDTQQELTAADRVGSGEGGDVGEQRPGRGTVLRLSLQEFCVLIAALYPEYIYTVLKYPVQMSLPSLTAHLHQDVIHAVVNNTHKMPPDHLPEQVKAFCITPTQWPAMQLNKLFWENKLVQQLCQVGPQKSTPPLGKLWLYAMATLVFPQDMLQCLWLELKPQYAETYASVSELVQTLFQIFTQQCEMVTEGYTQPQLPTGEPVLQMIRVPRQDTTTTDTNTTTEPGLLDVFIQTETALDYALGSWLFGIPVCLGVHVADLLKGQRILVARHLEYTSRDRDFLRIQRSRDLNLSQLLQDTWTETPLEHCWLQAQIRRLRDYLRFPTRLEFIPLVIYNAQDHTVVRVLRPPSTFEQDHSRLVLDEAFPTFPLYDQDDNSSADNIAASGAAPTPPVPFNRVPVNIQFLRENPPPIARVQQPPRRHRHRAAAAADDDGQIDHVQDDTSRTADSALVSTAFGGSVFQENRLGETPLCRDELVAVAPGAASTSFASPPITVLTQNVLSALEILRLVRLDLRQLAQSVQDTIQHMRFLYLL",
    "output": "Large tegument protein that plays multiple roles in the viral cycle. During viral entry, remains associated with the capsid while most of the tegument is detached and participates in the capsid transport toward the host nucleus. Plays a role in the routing of the capsid at the nuclear pore complex and subsequent uncoating. Within the host nucleus, acts as a deneddylase and promotes the degradation of nuclear CRLs (cullin-RING ubiquitin ligases) and thereby stabilizes nuclear CRL substrates, while cytoplasmic CRLs remain unaffected. These modifications prevent host cell cycle S-phase progression and create a favorable environment allowing efficient viral genome replication. Participates later in the secondary envelopment of capsids. Indeed, plays a linker role for the association of the outer viral tegument to the capsids together with the inner tegument protein."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVATCLQVVGFVTSFVGWIGIIVTTSTNDWVVTCSYTIPTCRKMDELGSKGLWADCVMATGLHHCKPLVDILILPGYAQACRALMIAASVLGLPGILLLLTVLPCIRMGHEPGVAKYRRAQLAGVLLILLALCAIVATIWFPVCAHREITIVSFGYSLYAGWIGAVMCLVGGCVIVCCSGDAQSFGENRFYYSSGSSSPTHAKSAHV",
    "output": "Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASINDNYLKLKAGYLFPEIARRVNAFTTANPNAQVIKLGIGDVTEPLPLACRQAMAKAIDDMGDRQTFKGYGPEQGYAWLREKIAQHDFQARGCEVNAEEIFISDGSKCDTGNILDIFGKDNTIAVTDPVYPVYVDTNVMAGHTGDANEKGEYGGLVYLPISAENDFVAAIPSKKVDLIYLCFPNNPTGATATKAYLKQWVDYALAHGSIIFFDAAYEAFITDPTLPHSIYEIEGARDCAIEFRSFSKNAGFTGTRCALTVVPKTLTAKAADGSDVELWKLWNRRQSTKFNGVSYIIQRGAEAVYSPEGQAQVQELIAFYLENARIIREKLAAAGLQVYGGINAPYVWVKTPHGLSSWDFFDKLLHTVNVVGTPGSGFGAAGEGYFRISAFNSRANVEEAMERITSTLKLG",
    "output": "Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPKGSGKVLSQNKKANHDYFIEETYETGIVLQGTEIKSIRAGRVNMKDSFAKIERGEVFLHNMHISPYEQGNRYNHDPLRTRKLLMHRKEINKLIGLTKEKGYSLVPLKLYLKNGFAKVLIGLGKGKKTYDKREDLKRKDAKREIERAFRDRQKGF",
    "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNITQAYKRSLWWSMDMVGATGSVERKMLTAVGLQFLAAGGMAFLTVFTAGTVQLIGVGGMLALSVVAFYNTYLIAEADFVEPLVALEDAADDIAAGEFERADIPSSKRDDEIASLVASFDGMQSNLEVASRQADALARQAFDDPALDESVPGAFGESITEMADSLEAYTAELEDKTAELEHQQAELERQSEQLRALVDALSEATDAARAGDLTATVDAAALDVTDDHRAAVEDFNQLLETLADTISDIQSFSDAVLAVSRTTDERVDAVADRSAAVSESVTEIADGANQQTNQLNNIAAEMDTVSATVEEIAASANDVAKTAQAAADRGEDGRGEVEETIEALRALREQSQAVAETVESLAAEVERIDGITALIEDIAEETNMLALNASIEAARTGSDGDGFAVVADEVKDLAEETREQAADISEIVDAVTEKAEDASIAIGEVDAEVERKITKAEGVLRDFEAIVDEVANVNHAVQEISDATDQGAQSVTDVVGMVEEVASVSEETAAESDTVADNAAEQTDATDEVADQMDELAEQTAALAGMLDDFTVPADAGTADQSVADDSPTAQPPAADDEPAAAVVDQPQPASDAEDEEGVPDSGGESVAVSDGGWADDRSSFTWADSQ",
    "output": "Mediates bacteriorhodopsin- and halorhodopsin-dependent photoresponses by detecting membrane potential changes. Probably transduces the signal to the histidine kinase CheA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDSRTGELLTYTQCQTGCYFDDIKNPIYFRLQNTTTMATGNKIITLQIRANHNLRKVLGLQICWLNLVVLSVSPRLSGEALLDRFKFHVMKHLNNLGVISINNVIRSINHFIDLFDQRVFYAPSFYYNIKMRLY",
    "output": "Increases viral DNA accumulation. Enhances infectivity and symptom expression (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRNNNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKAYIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGASAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNEK",
    "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLSKTHIMFIPFPAQGHMSPMMQFAKRLAWKGVRITIVLPAQIRDSMQITNSLINTECISFDFDKDDGMPYSMQAYMGVVKLKVTNKLSDLLEKQKTNGYPVNLLVVDSLYPSRVEMCHQLGVKGAPFFTHSCAVGAIYYNAHLGKLKIPPEEGLTSVSLPSIPLLGRDDLPIIRTGTFPDLFEHLGNQFSDLDKADWIFFNTFDKLENEEAKWLSSQWPITSIGPLIPSMYLDKQLPNDKGNGINLYKADVGSCIKWLDAKDPGSVVYASFGSVKHNFGDDYMDEVAWGLLHSKYNFIWVVIEPERTKLSSDFLAEAEEKGLIVSWCPQLEVLSHKSIGSFMTHCGWNSTVEALSLGVPMVAVPQQFDQPVNAKYIVDVWQIGVRVPIGEDGVVLRGEVANCIKDVMEGEIGDELRGNALKWKGLAVEAMEKGGSSDKNIDEFISKLVSS",
    "output": "Component of the dammarane-type triterpene saponins (e.g. PPD-type ginsenosides or panaxosides) biosynthetic pathway . Glycosyltransferase that catalyzes the biosynthesis of ginsenoside Rh2 from protopanaxadiol (PPD) and the conversion of compound K to ginsenoside F2 ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALALY",
    "output": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKALLDLFKQVQQEEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIEPGMTPLKARQIMTEEDYYNKVEEYGDEFRAEMGAEGVRELLRAINIDEQVETLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPEWMILEVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKEVENQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEARTLMLASNNVLFPANGDPSIVPSQDIVLGLYYATREAVNGKGEGLSFTGVSEVIRAYENKEVELASRVNVRITEMVHNEDKSEGAPPFVPKITLYATTVGRAILSEILPHGLPFSVLNKPLKKKEISRLINTAFRKCGLRATVVFADQLMQSGFRLATRAGISICVDDMLVPPQKETIVGDAAKKVKEYDRQYMSGLVTAQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGNETRQESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVAVADVVNPETQETLYESGTLLDETAVEEIERLGIDEVRVRTPLTCETRYGLCAACYGRDLGRGSLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSNGIVRFTATMRYVTNAKGEQIVISRSGEAMITDDFGRERERHKVPYGATLLQLDGATIKAGTQLATWDPLTRPIITEYGGTVKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKSVRPQVKLLDANGEEVKIPGTEHAVQIGFQVGALITVKDGQQVQVGEVLARIPTEAQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEKQVLVHDAQVVNKGEMIVDGPADPHDILRLQGIEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQITDNGDTRFIPGEQVERSDMLDENDRMIAEGKRPASYDNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAFHKARKAKESSDRERFDQIAAEEAFDFGTPSAPAEEPQHPAAE",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTMPYYASAEQIMRDRSELARKGIARGRSVVVLTYRDGVLFVAENPSRALHKVSELYDRLGFAAVGKYNEFENLRRAGIVHADMRGYSYDRRDVTGRSLANAYAQTLGTIFTEQPKPYEVEICVAEIGRFGSSTPAQLYRITYDGSIADEQEFVVMGGTTEPIVTAMRESYQRDLDLESAVRLAVGALQKGGPAPAGTTEAEPRTLDVSALEVAVLDSNRPRRAFKRIAGSALEEMLPTPAATEDAPANGDAPS",
    "output": "Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPKAQRVIKDLIKVAVKVAVLHRSGCFGPGELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLVECRDILLELVEHHLTPKSHDRIRHVFDHYSDPDLLAALYGPDFTQHLGKICDGLRKLLDEGKL",
    "output": "Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGKEKGHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEATELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYNVTVIDAPGHRDFIKNMITGTSQADCAILIIGGGTGEFEAGISKDGQTREHALLAYTLGVKQLIVAVNKMDTTGWSQARFEEIVKETSNFIKKVGFNPKTVPFVPVSGFQGDNMIEPTTNMPWYQGWQKETKAGVVKGKTLLEAIDSIEPPARPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMIVTFAPAGVTTEVKSVEMHHESLDAGLPGDNVGFNVKNVSVKDIRRGNVCGDSKNDPPMGCASFTAQVIILNHPGQISAGYSPVLDCHTAHIACKFAELIEKIDRRSGKKIEESPKFVKSGDACIAKMVPSKPMCVEAFTDYAPLGRFAVRDMRQTVAVGVIKAVEKVAPGAAKVTKAAVKAGAKK",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MYSLARPLLFSLDAERAHALALRSIDTAYRTGTTSLLSTRPVPLPTPAFGLMFPNPVGLGAGLDKNGEHIDALLALGFGFVEIGTVTPRAQDGNPKPRMFRLPEYQAVINRMGFNNLGVDALVANVQRARRRGGLLGINIGKNKDTPNEEATSDYRYCMERVYPLADYITVNISSPNTAGLRELQEEQSLRRLISDLRETQEALGAQHGKRVPMLVKVAPDLNDRDIDAAARVLADLAVDGVIATNTTVTRPLIANHPLAAEAGGLSGAPLLGQSTLVLRRLRARLPESIPLIGVGGINSGADAVAKMAAGASLVQCYSGLVYRGPQLVGECVNAIRRRREAPSSGAVAPL",
    "output": "Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDLVRGLWRKHRRKILVTTTCLGSGYLLYKLYNAHTRKLADLERELANERENDEIIKTQMKAHFDNIQMIADTTTLPHAIHHLSSRVVEEIDVSSIMDKLSKGKGILIPSEKLQLWNELKILSFTRMVLSLWSVTMLSLYIRVQVNILGRHLYIDTARGLGSSHLLDELDLIERDDEQKFLTSADFLATSGMPSLISNMQNAVKEVLKGKQLKDVLTTSALRETVMRILDVFMSTGSPHHWVDYLMMSQDATTDVSSSDATVTKFHLLITETREVLTSNDFSNVAEISLKCCAVALVEEMETQTGLATGMQLAKLLPQIEKTMPEISAEPEKNRFLQLIRDLPEVKLFFTLLYANMPQ",
    "output": "Involved in morphology determination of peroxisomes, but not in import of peroxisomal matrix proteins. May act as a docking factor for PEX19 and be necessary for the import of peroxisomal membrane proteins in the peroxisomes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEPKRIREGYLVKRGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVFKITTTKQQDHFFQAAFLEERDSWVRDTKKAIKCIEGGQKFARKSTRRSIRLPETVDLGALYLSMKDIEKGIKELNLEKDKKIFNHCFTGNCVIDWLVSNKSVRNRQEGLMIASSLLGEGYLQPAGELSKNAADGMAEHPFLDNPDAFYYFPDSGFFCEENSSDDDVILKEEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAAGGEEPLGAIHLRGCVVTSVESNPDVRKSEEENLFEIITADEVHYFLQAATPKERTEWIKAIQVASRTGK",
    "output": "Major protein kinase C substrate of platelets."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MYLEKLSLTDFRSYAQVDLTLEPGVTVLVGYNGIGKTNLMEAIGYLATLSSHRVSSDAPLLRFGTERALIRAKLVRGGQSTVLELEINGSRANRGRINRSNPVRARDILGICQTVLFAPEDLALVKGDPSNRRRFLDELLVSLMPRHSATRTDYDRVLKQRNALLKSGRSGKFTAGHEATLDVWDQHMARAGAELLYARLELVERIRPHLKAAYAQLTDGSKEADAIYRSTLQGILDDDGAGAGYAAEPAAVERVEDLRALSVEELTQRYVQAFAASRRKELERGISLVGPHRDDVELILGEAPAKGYASHGETWSMCLSLRLASYYVMLDDARTGGSAPILILDDVFAELDVQRRRKLAAIVSGAEQVLVTAAVDADIPDELAGRRVKVVPGGIDESESR",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQIVDRSNLEASLKLALSPENNPKRNFVQSVEIIVTFKEVDMKKGDLKLREIVVLPKPPEKTKKVLVVPTIQQLEYAKKAEPNTILTKEELQKLQGNKRAIKKIARQNDWFLIAPDSMALVGRILGPALGPRGKFPTPLPNTADISEYILRFKRSTLVKTKDQPQTQVFIGTESQQIADLAENALAVLNVIESKGYAQKVRNIYVKTTMGKVVKVELR",
    "output": "Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA (Probable).; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKNKNSEQNTHSTIGEQDIHYFHEGKHIYAYEFMGAHKACEEGIEGIRFTTWAPNAKSICVIGDFNYWQVEDKNYMEPITDAGLWSVFIPNAKNGDKYKFVVTNKDTNNYVYKSDPYAFFSELRPNTASIITTETQYTWSDDKWLEKRAKTNYYDNPMNVYELHLASWKTKNGKFLTYDELNETLPQYIKEMGYTHVEFMPLHEHPLDASWGYQPTGFYSVNSRHGDIIGLKRLVDKLHNNDIGVILDWVPGHFCKDQHGLIYFDGSPCYEYQEPTKAINKGWGTHNFDLGRNEVKCFLISNAMYWINEFHIDGLRVDAVSNILYLNYDREDGQWIPNIYGGHENLEGIAFLKELNGVLKHTCKGVITIAEESSSWPDISTPVEKGGLGFDFKWNMGWMNDTLRYISLDPVYRKYHHNLITFSMVYHYSEKFILSISHDEVVHGKKSLINKMWGDLWNKYAGLRLYMSYMIGHPGKKLIFMGSEFVQFVEWREYEQLQWQVVDQYESHKQTLHFFKKLNDLYHNETALWQCDYDHHGFRWIDADNSQQSILSFIRSSKDNKQKLIFICNFTPVTYYDYHLGVPDAGSYKEVFNSDNLEFGGSGQVMATEIFSSPQSSHGFEQRITIKIPPMATLVLKLIK",
    "output": "Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARIAGVNIPTAKRVPIALTYIHGIGNHVAEQICDAVGIDRARRVNQLSDAEVLAIREYIDANVTVEGDLRRETSMNIKRLMDLGCYRGLRHRRGLPVRGQRTHTNARTRKGPAKAIAGKKK",
    "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVNRLILMVVVVFITDSVMGTAEVMSHVTAHFGKALEECREESGLPVEVMDEFKHFWREDFEVVHRELGCAIICMSNKFELLQDDTRIHHVKMHDYIKSFPNGQVLSEKMVQLIHNCEKQYDDIADDCDRVVKVAACFKKDAKKEGIAPEVAMIEAVIEKY",
    "output": "Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSDSDSEFSIEDSPKKKTAPKKEKASPKKKKDDANESMVMTEEDRNVFTSIDKKGGGSKQMAIEDIYQKKSQLEHILLRPDTYIGSVEHTEKTPMWVYNMEESKLEQRDISYVPGLYKIYDEILVNAADNKQRDPKMNTIKITINKEKNEISVYNNGKGIPVTQHKVEKVYVPELIFGTLLTSSNYNDDEKKVTGGRNGYGAKLCNIFSTKFTLETSSRDYKSAFKQTWIKNMTRDEEPKIVKSTDEDFTKITFSPDLAKFKMKELDDDICHLMARRAYDVAGSSKGVAVFLNGKRIPIKGFEDYVQMYTSQFNNEGEPLKIAYEQVGDRWQVALALSEKGFQQVSFVNSIATTKGGRHVDYVADQMVAKFIDSIKRKLTKTSMNIKPFQIKNHMWVFVNCLIENPTFDSQTKETMTLQQKQFGSTCVLSEKFSKAASSVGITDAVMSWVRFKQMDDLNKKCSKTKTSKLKGIPKLEDANDAGTKNSQQCTLILTEGDSAKTLAVSGLSVVGRDKYGVFPLRGKLLNVREGNMKQIADNAEVNAMIKILGLQYKKKYETEDDFKTLRYGKLMVMADQDQDGSHIKGLVINFIHHFWPSLIQRNFVEEFITPIVKATKGKEEVSFYSLPEYSEWRMNTDNWKSYKIKYYKGLGTSTSKEAKEYFLDMVRHRIRFKYNGADDDNAVDMAFSKKKIEERKDWLSKWMREKKDRKQQGLAEEYLYNKDTRFVTFKDFVNRELVLFSNLDNERSIPCLVDGFKPGQRKVLFACFKRADKREVKVAQLAGAVAEISAYHHGEQSLMGTIVNLAQDYVGSNNINLLLPIGQFGTRLQGGKDSASARYIFTQLSPVTRTLFPAHDDNVLRFLYEENQRIEPEWYCPIIPMVLVNGAQGIGTGWSTNIPNYNPRELVKNIKRLIAGEPQKALAPWYKNFRGKIIQIDPSRFACYGEVAVLDDNTIEITELPIKQWTQDYKEKVLEGLMESSDKKSPVIVDYKEYHTDTTVKFVVKLSPGKLRELERGQDLHQVFKLQAVINTTCMVLFDAAGCLRTYTSPEAITQEFYDSRQEKYVQRKEYLLGVLQAQSKRLTNQARFILAKINNEIVLENKKKAAIVDVLIKMKFDADPVKKWKEEQKLKELRESGEIELDEDDLAAVAVEEDEAISSAAKAVETKLSDYDYLVGMALIKLSEEEKNKLIKESEEKMAEVRVIEKKTWQDLWHEDLDNFVSELDKQEAREKADQDASIKNAAKKLAADAKTGRGPKKNVCTEVLPSKDGQRIEPMLDAATKAKYEKMSQPKKERVKKEPKEPKEPKKVKKEGQDIKKFMSPAAPKTAKKEKSDGFNSDMSEESDVEFDEGIDFDSDDDGVEREDVVSKPKPRTGKGAAKAEVIDLSDDDEVPAKKPAPAKKAAPKKKKSEFSDLSGGDSDEEAEKKPSTSKKPSPKKAAPKTAEPKSKAVTDFFGASKKNGKKAAGSDDEDDESFVVAPREKSGRARKAPPTYDVDSGSDSDQPKKKRGRVVDSDSD",
    "output": "Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (By similarity). Essential during mitosis in the adult germline and during embryogenesis for proper segregation of daughter chromosomes . Required for centromere resolution during mitosis . Required for chromosome segregation in anaphase of meiosis I during spermatogenesis . Promotes cleavage furrow stability during cytokinesis upon the presence of chromatin obstructions . Promotes DNA break formation upon zygotic genome activation in the Z2 and Z3 primordial germ cells in L1 larvae, thereby activating a checkpoint response . Essential for embryogenesis ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAPAVAVVAAAAAFPFRLFSAEARRNTKGSRSKRGSARPLKPSPPPRPSASSSAAGGGGATTFTRLPLRNAPASVEVTLDRFPTANPEPRASTFTRRNGERLGDDEEDEEEEEDEVELGLRGATTFARLPLRDSPDGGDLTIGHFDAGVAPQEGLRSRAISRQLVEHLDDVEEEEEEQVVSRLDIFEGAKGREARAFLPDEDDEDDDVVVFDPEYDGYSDDEEFVATAVEQSPRGDAIAVAELEKLKYDNDDDDDDDDEVVVFHPDDDEEVDVFEDYDDDEEEETKEKGVPAVMRCFDTAKIYAKAGDGGNGVVAFRREKYVPLGGPSGGDGGRGGNVFVEVDGDMNSLLPFRKSVHFRAGRGAHGQGRQQAGAKGDDVVVKVPPGTVVRSAAGDVELLELMRPGQRALLLPGGRGGRGNAAFKSGTNKAPRIAEKGEKGPEMWIDLELKLVADVGIVGAPNAGKSTLLTAISAAKPTIANYPFTTLLPNLGVVSLDFDATMVVADLPGLLEGAHRGYGLGHEFLRHSERCSVLVHVVDGSGEQPEYEFEAVRLELELFSPSLVDKPYIVVYNKMDLPEASERWNKFQEKLQAEGIEPYCISAMNRQGTEDVVLAAYKVLQKDRQRMKDDEEWNGPENLNHVADAIKRERRAPMNEFEIFHDKGTNTWNVVGAGIERFVQMTNWQYSESLKRFQHALEACGVNKTLIKRGVKEGDTVVVGEMEMVWTDEPSKTRSSKTMNSKDDSVRWPEFG",
    "output": "Probable GTP-binding protein that may play a role in chloroplast development."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFAEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMFAKHFGWKIGKFFYFVNNLHIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI",
    "output": "Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MWIQQLLGLSSMSIRWPGRSLGSHAWILIAMLQLAVDFPSCDSLGPGPEFRLLSRPQRPQRLWSLRSGPPTRLPTPAWSPRAARAERAHGPIQMQTPRARRAHRPRDQVATLGPKGGLTKPPAATRSSPSLASATASSSIVTAGAAEHQGLLRRGRRHTHDTEFNDFDFRGGRPTTETEFIAWGPTGDEDALESNTFPGGFGPTTVSILQTRKTTVATTTTTTAASTATAMTLQTKGVTESLDPWKRTPVGVSTTEPSTSPSSNGKDIQPPRILGETSGLAVHQIITITVSLIMVIAALITTLVLKNCCAPSGHTRRNSHQRKMNQQEESCQNLTDFTPARVPSSVDIFTAYNETLQCSHECVRASVPVYADETLHSTGEYKSTFNGNRTSSADRHLIPVAFVSEKWFEISC",
    "output": "Plays a role in cell adhesion and cell migration."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLTVFFIADGVFQLLSGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLEADALRRELANYDVILRF",
    "output": "Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIQFQRLHKSYSVDGRQIVALHPLDLRIGPGEVFGIIGHSGAGKSTLIRLINRLEEPSGGRLLIGDEDVTALDGQGLRALRRRIGMIFQHFNLLSSRTVAGNVAFPLELAGTPRAEIDARVAELLARVGLQEHANKYPAQLSGGQKQRVGIARALATRPQILLCDEATSALDPQTTASVLQLLAQINRELGLTIVLITHEMDVIRRVCDRVAVLDAGKLVETGPVTEVFLHPKHATTRRFVSEAEHVDEAELHRDFAAVGGRIVRLTFLGNGTYEPVLGRIARETGVDYNILSGRVDRIKDTPYGQLIVALTGGDQNAARAGFVAAGVQVEDLRV",
    "output": "Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSGWRLLLTRPDEECAALAASLGEAGVHSSSLPLLAIDPLEETPEQRTLMLDLDRYCAVVVVSKPAARLGLERLDRYWPQPPQQTWCSVGAATAAILEAYGLDVTYPEQGDDSEALLALPAFQDSLRVHDPKVLIMRGEGGREFLAERLRGQGVQVDYLPLYRRRAPDYPAGELLARVRAERLNGLVVSSGQGLQNLYQLAAADWPEIGRLPLFVPSPRVAEMARELGAQRVIDCRGASAPALLAALTSAA",
    "output": "Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNLMLQNLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEELQQRQLAEKQEKINAFLELMKADGINPEELFAMDSAMPRSAKKRQPRPAKYRFTDFNGEEKTWTGQGRTPKPIAQALAAGKSLDDFLI",
    "output": "A DNA-binding protein that acts in a fashion similar to H-NS, repressing gene transcription. A subset of H-NS/StpA-regulated genes require auxillary proteins for repression; these auxillary proteins (Hha and other similar proteins) may also modulate oligomerization of the H-NS/StpA complex (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNLIAKLEQEEIERALAGKTIPEFAPGDTVIVNVNVVEGNRKRVQAYEGVVIAKRNRGLNSSFIVRKISSGEGVERTFQTYSPLLASIVVKRRGDVRRAKLYYLRERSGKSARIKEKLVSKDRAAAAQQ",
    "output": "This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPSQSRSRDRYRGRDTEYTRRRYPDEHDYSHDDHDYDYDDDDDDNDDLEQDVTERRYRRDGYRRPRGESRARAYYERDAAAAAAHDEELLAEERERRRAGASGSPRKSGQHRERDRDRERDREAQSRRRTYEDDGRHRTRDGRRERRREGGGEGGRRERRRGESRRGEAARKHQSSDSTNSASHLLSADALARLGSQYEKEDRRERAHAKDAAKAERKRRKKRAVVGEQERGLRAEKPRDRSRARVASGAYMEEGRGPEMEFRRRGGGGPPMDARWPKGGGWGGSVDGGDAGRPFWKQKKWLIGIGVVILILVIVIPVAVVVSKKHNDKPNATTTQPDGTTPSNSNLDGLSPDSIPGYAKGTFLDPWTWYDTNDFNVTFTNETVGGLSLMGLNSTWDDSARPNDNVPPLNKPFPYGKQPIRGVNLGGWLSLEPFITPSFFQSYSALSGVIDEYTLTQKLGSTAGARLEKHYATFITEQDFADIRDAGLDHVRIQYSYWAVTTYDGDPYVAKTSWRYLLRAIEYCRKYGLRVKLDPHGIPGSQNGWNHSGRQGAIGWLNGTDGELNRKRSLEVHDQVSKFFAQDRYKNVVTIYGLVNEPLMLSLSVEDVLNWTVEATKLVQKNGITAYIALHDGFLNLSKWKSILKTRPDNMLLDTHQYTIFNTGQIVLNHTARVNLICNDWSAMIKEVNSTSGFGPTICGEWSQADTDCAQYLNNVGRGTRWEGTFSLTDSTQYCPTADSGPRCSCANANADPSAYSADYKKFLQTYAEAQMSAFETGQGWFYWTWRTESAAQWSYRTAWKGGFMPQKAYSPSFKCGDTVPDFGSLPEYY",
    "output": "Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSENPVKRPGKDGSRNKFKPVQEEGGTPGWFRSKGESPQGKFPGFLLFLMAGLLMLFVFLRFFSGTDAPEITYNEYKSVLSRALVTEVTVKTYEDKSAILSGKLNAPAQLQLIDKTTLQTNRFAVRVPSFTLEQADMLTEKGVRLKVEKGSSDLNTFLALFAPWIIFAALYFFLFRRMSGQNGAQAKNIFSFGKSRAKMVSEFEVKTTFKDVAGVDEAIEELQETVEFLTNPEKFQKIGGKIPKGVLLLGPPGTGKTLLAKAIAGEAKVPFFSISGADFVEMFVGVGAARVRDLFEQAKKNAPCIIFIDEIDAVGRSRGAGLGGGHDEREQTLNQLLVEMDGFTTNENVILIAATNRPDVLDSALLRPGRFDRQITIDKPDIRGREAILKIHTRNTPLDGDVDITVLAKSSPGFSGADLANLVNEAALLAARHEQVLITAVNFEQARDKILMGPERRSMFISDEQKKLTAYHEAGHVLVSIHTKGSDPIHKVTIIPRGRSLGLTAYLPLEDRYTHNREYLLAMITYALGGRVAEELVFQECSTGAANDIEKATDIARRMVRQWGMSESLGPINYGDSHKEVFLGKDYSHIREYSEETALQIDVEVRNIIMGCMENAKTVLSEQLAVLHRLAGILIEKESLNAREIQEITGPGQGALPNPVTA",
    "output": "Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTEARPIILTCGEPAGVGPELAPKALASGVPFVFLGDPRHLPEGTAWAEVTAPGEPVADGVLAVLRHDFPAPARPGQPDPANAPAVIEVIARAVDLAMSGAAGGICTLPINKEALKRGAGFGFPGHTEYLAHLAGDVPVVMMLASTTVQPPCRVVPVTIHIPLSEVPLALTPLRLEQAIRITDAAMRRDFGLAQPRLAIAGLNPHAGENGVMGDEEARWMAPLIERLRREGFDLRGPLPADTMFHPAARARYDAALCAYHDQALIPIKTLDFAGGVNITLGLPFVRTSPDHGTAFDIAGQGIADAESVIAALRMAHEMAARR",
    "output": "Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNHHEVHAVSAFAMSGFEQSLVFAIDGGGDFLSGLMAVGSGTVIAQLVSFPEHNSLGLFYLETIRYLGCGMFDEYKVMGLAPYGDPDRYRELFAQFYELLDSGGYRVHLDRIGPALLRNIQVRRKGMPFTQQHRDVSASLQEALERIVFHTLRHHRKATGMTRLCLAGGVAHNCTLNGKLLYSGLFDDIFVQPAAHDAGCALGAALMVSSELGRPAPRERLPDVYWGPDLGNEQATELELNAWSGHLDIQRSDDIASSAADWMANGAVIGWVQGRSEFGPRALGNRSILADPRPAENKDRINAVVKKRESYRPFAPSALEEDASEFFELPDGTRQLPFMNFVVRVREAKGNVLGAITHVDGTARLQTVSRKTNPAYWDVINAFKKRTSLPILLNTSFNNNAEPIVQSVSDAITTFLTTDLDGLVVGPFLVRKRPASLQDWSALAASLPPYASLHRVRSHIAPDRQETVCEIRMGHSAHSSMRISPELFEILMRIEGEASLGSLFDTALLDQAKREDLVKELRLVWELRGVRLHPLHAACRHDNVQSGT",
    "output": "Involved in 6-O-carbamoylation of Nod-factors."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSESEVRQTEVIPQWKREEVDELVDFIESYESVGVVGVAGIPSRQLQSMRRELHGSAAVRMSRNTLVNRALDEVNDGFEELKEYIAGQVALIGTNDNPFALFKELEASKTPAPINAGEVAPNDIVIPEGDTGVDPGPFVGELQQVGASARIMDGSIMVTEDSNVLSEGEEVSEELANVLAELGIEPKEVGLDLRGVFSEGVLFEPDELAIDVDEYRADIQSAVSAATNLSVNAVYPTAQTAPTLIAKATSEAKAVGLFANIESPDFMPELISKADAQLRALAANIDDEEALPEELRGVSAADTGAAEEEESTDEEAADADQADAAEDDDAADDDGDDEDAGDALGSLF",
    "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKKKLGLLAMVVALMAIATGCSETGQPITSKSTGIWNEYFVYPLSQLITYFADLFNSNYGLAIVITTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSKDQATQQKLQQEMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMRTAEIKQHSFLWFDLGHADPFYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFGIAQMYFIKGPEIKASKAGKAGGSSK",
    "output": "Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEMSFRWYGEDDPVTLENIGQIPTMKGIVTAIYDVPVGEVWSRERIQQLKEKVEAAGLKISVIESVPVHEDIKLGRPTRDLLIDNYIQTVKNLAAEGIDTICYNFMPVFDWTRTDLAYQYPDGSTALIFDETVSKKMDPVNGELSLPGWDASYSKEEMKAIMDAYAEIDEEKLWENLTYFIKRIIPEAEAVGVKMAIHPDDPPYSIFGLPRIITGLEAIERFVKLYDSKSNGITLCVGSYASDPQNDVLEISRRAFELDRVNFVHARNIKLGDGKSFKESAHPSEYGSIDMYEVIKLCHEFGFEGAIRPDHGRMIWGETGRPGYGLYDRALGATYVSGLYEAVIKGSK",
    "output": "Catalyzes the dehydration of D-mannonate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEEHQALVIDNGSGMCKAGFAGEDAPRAVFPSLIGRPLQRSIMVGMGNKDAYVGDEAMSKKGILALKYPIEHGIITNWDDMEKIWHHTFYNELRVGPEEHGVLLTEAPLNPKANREKMTQIMFETFRVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILMERGYSFNTSAEREIVRDIKEKLCYIAFDFEGEMKKASESTAVDTSYELPDGNIITIGNERFRCPEVLFQPNFIGMEAAGVHETAFNSIGKCDIDIRKDLYSNVVLSGGTTMFEGIAERMTKELTAMAPASMKIRVVAPPERKYSVWIGGSILSSLSTFQSMWITAEEYEDAGCGIVHRKCF",
    "output": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKVSELNLKAKSLLEFHLDDIELSGEISKITIHGSGHWYFDLKDEKSSIACVMFKGFNQFVQTQPKVGDMLDLRGYVSLYEASGRYQFIAKSMQKTSLGDLEAKFLALKEKLEKEGLFDINAKKSIVKFPKKIGIITSFTSAALQDMLKLISQKEYNLCKITIFNALTQGQSAPNSLINALKKANEYDLDAIILARGGGSREDLFCFNDEELARCIFSLKTPVVSAIGHEIDYVISDFVADLRAPTPSAAIDMIFPNKLSLEQGLDELTMRFKSQMLNHLKFYQNKIDHLQNLAKAKSLENAFFLRKQKLDFLQSQLKSVLNLKLLNYENKLNNFEELLAQHKNFFDKSKNLINLQKDGKNISLEKLKKGDIIKLCSINESKEAQIL",
    "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEVILLEQVVNLGKLGDKVAVKSGYARNYLIPQGRAVSATKENEAHFESRKAELEKAAGDKVAVAERCKQALADLGSVTIPAKAGTEGKLFGSVGAADIAEALTKAGVEIGKKEVRLPEGALRQVGEYELVIHLHPTVEAPIKVVVTGEEE",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKSLSILGSTGSIGLSTLDVVRQHPEKFNVTGLAEGHDINLLAEQIKEFRPDIVSVRDKASAGLLREQLGSEKPEILWGIEGAAAVGAAEGSEMVVSAIVGAAGLVPTVSAIKAGKDIALANKETLVVAGQLVSDLVKEHKVTLLPVDSEHSAIFQSLSGHRKEDIERIILTASGGPFRHTSAEDLRHVGPEKALKHPQWTMGAKITIDSATLMNKGLEVIEAHWLFDMPADKIGVVVHPQSIIHSMVEYIDGCVMAQLGAPDMRAPIAYALAWPERCESGIKKLDLTQIGTLTFEQPDMERFPALRLAFDALKAGQTFPAVLNAANEIAVAAFLDKKIGFTDIPAIADRTMQAHDPYTPSGLDEYLAADRWARDTAKTMTN",
    "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRQYHNLMKEVLAKGVQKSDRTGTGTISVFGHQMRFNLADGFPMVTTKKLHMKSIVYELLWFLKGSTDNNWLKERGVSIWNEWAAPDGDLGPIYGYQWRSWPAPNGQHIDQISEVVETIKKNPDSRRIIVSAWNVADIPRMALAPCHAFFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHMVAQQCNLEVGDFIWTGGDCHLYSNHLEQVDLQLSRDFLPLPKLNILRKPDSLFDYEFEDFEIVGYESHPHIKAPVAI",
    "output": "Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNYFPIFANLAGRPVLVVGGGSVAARKISLLLDAGAQVRVVANQLNAELSALAAENKILWLAEEFRAEHIRTVFLIIAASSDQALNRRVFQLAESCQKPVNVVDDRDYCSFIFPSIINRNPIQIAVSSSGSAPVLARLLREKLEALLPHSLGDMAEISGRWRDAVKAKLKSVTERRRFWEKQFNGRFAALVKNQQTAQAEQELAKQLEQNYQGGFVSLVGAGPGDAGLLTLKGLQEIQQADVVLYDALVSDGILSLVRRDAERIFVGKRARGDRTPQEDTNALMVRLAREGRRVVRLKGGDPFVFGRGGEELETLARHQIPFSVVPGITAAVGATAYAGIPLTHRDYAQSAVFVTGHRKADAPDIEWQTLARSRQTLVIYMGALKAALIAERLQQHGRSPDTPAAVISQGTLPAQKTATGTLANLAELAETAPNPALIVIGEVVGLHEKLAWFGENGEGENRVGQAYPALGGLNAGQRAA",
    "output": "Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMTESEFIRASEALFEHIEDQIDENGWDFDCRFAGNVLTIEAGDGAQIIVNRHTPNQELWIAAKSGGYHFAEQNGKWLATRDGRDFYDVLNEALSAASGEAVEIAEL",
    "output": "Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQVEHEVATEGGQAPASSGHRKGIAGLAVAAIGVVYGDIGTSPLYTLKEVFNGPHAVPVNEANVYGILSLVFWALVTVVSAKYVVFITRADNRGEGGIMALTSLALRVVQPGRRAWWLSVLGVFGAALFYGDGMITPAISVLSAVEGLEVATPAFKPFVIPIALVVLVGLFVMQRRGTGSVGAIFGPVMVCWFLVLAVLGINGITLHPEIIGALDPRWAARFFIDQPLIGWLALGAVVLAITGGEALYADMGHFGRRPIKLAWFSLVFPALYLNYLGQGALILDHPDNVRNPFYMLVPDALVYPMVGMATLATIIASQAVISGAFSLTRQAIQLGYAPRMQTLHTSEHEIGQIYVPGVNWMLLGAVVALVVGFQSSSALASAYGIAVTLTMMIDTVLAFVVVRSLWKWGRAKAVLFLVVFLAVDIAFFSATTVKIFAGGWFPLLIGAAIFTLLRTWKRGRSLLNERIRSDTMPLDIFIQSMFQSPPPRVEGTAVFMTTWLDGVPRALLHNLIHNKVLHERVVLLRVDTADVPHVPEGERVEVEEIDYGFYRVRVHYGFKDDPDIPAALGLCAQRGLPFDMMETSFFLGRETLVSRVGSGMPQWREKLFILLFRNAGSAADYFCIPPNRVVELGTQVEL",
    "output": "Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMWHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARHGCAPALPFLPPGAP",
    "output": "Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRSALLLACLLATASAFSVRSWLRRARAGDSEENAVLKSRHRYYLYRYAYPPLHRYKGSDSSEEEGDGSEEEEEGGAPSHAGTQAAGEGLTLGDVGPGGDAASAHQDCKGGQKGTRGDSGDEDSDEEEEEEEEEEEEEEVEEQDVSVNGTSTNTTAETPHGNNTVAAEEEEDDDEEEEEEEEEEEEAEATTAAATTAQDEVTTLGDEQRSEVTTAGEQWEYEVTVGARGDEGPTESSYGDQEEPARGDSYRAYEDEYGYYKGHGYDMYGQDYYYNQ",
    "output": "Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSHRVLVIGSGGREHAICWKLSQSPKVAQIYALPGSHGIQLVEKCRNLDAKTLDPKDFEAIAKWSKENQIALVVVGPEDPLALGLGDVLQSAGIPCFGPGKQGAQIEADKKWAKDFMLRHGIPTARYESFTDTEKAKAFIRSAPYPALVVKAAGLAAGKGVVVAANAKEACQAVDEILGDLKYGQAGATLVVEELLEGEEVSVLAFTDGKSVRAMLPAQDHKRLGNGDTGPNTGGMGAYCPCPLISQPALELVQKAVLERAVQGLIKERINYQGVLYAGLMLTRDGPRVLEFNCRFGDPETQVILPLLESDLFDVMEACCSGKLDKIPLQWRNGVSAVGVILASAGYPETSTKGCIISGLPAANTPTQLVFHSGLAVNAQKEALTNGGRVLIAIALDGSLKEAAAKATKLAGSISFSGSGAQYRTDIAQKAFKIASASTPGLSYKDSGVDIDAGDALVQRIKPLSRGTQRPGVIGGLGGFGGLFRLKELTYKEPVIAEATQGVGAKIHLALTHEFYENVGYDLFALAANDVLEVGAEPVAFLDYIACGKLQVPLAAQLVKGMADGCRDARCALVGGETAEMPSLYAPGQHDMAGYCVGIVEHSRILPRFDLYQPGDLLIGLPSSGLHCAGFNEILTQLAASKVNLRERSPVDGGDDGLTLAHVLATPTQLYVQQLLPHLQKGDEIKSVAHVTHGLLNDILRLLPDGFETTLDFGAVPVPKIFGWLAGKLKLSAQTILERHNCGIGMVLILPQSSQLWRTSLPGAKVLGVLQRRSKVSGSPVQVRNFVEQLEKVASPFGGLGDRELPEELKKLPSNSDLSAPREECFENAAGRRLTRIPTHYKDPILILGTDGVGTKLKIAQQTNRNTSVGIDLVAMCVNDILCNGAEPISFSSYYACGHWQEQLAKGVHSGVQEGARQANSSFIDSHSAALPLLYEPQVYDLAGFALGIAEHTGILPLLAEIQPGDVLIGLPSSGVHSNGFSLVHAVLKRVGLGLHDKAPFSDKTLGEELLVPTKIYVKALSTLLSRGKHGIKALAHITGGGLSENIPRVLRKDLAVRLDANKFQLPPVFAWLAAAGNISSTELQRTYNCGLGMVLVVAPTEVEDVLKELRYPQRAAVVGEVVARKDPKKSQVVVQNFEASLARTQKMLSQRRKRVAVLISGTGSNLQALIDATRDSAQGIHADVVLVISNKPGVLGLQRATQAGIPSLVISHKDFASREVYDAELTRNLKAARVDLICLAGFMRVLSAPFVREWRGRLVNIHPSLLPKYPGLHVQKQALEAGEKESGCTVHFVDEGVDTGAIIVQAAVPILPDDDEDSLTQRIHKAEHWAFPRALAMLVNGTALISPEVSSQ",
    "output": "Trifunctional enzyme that catalyzes three distinct reactions as part of the 'de novo' inosine monophosphate biosynthetic pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRTFNFLSFPQVHRQALVKAVLVAIATVSLLLTSDVINPQSAQAYPFWAQQTAPETPREATGRIVCANCHLAQKPAEIEIPHSVLPDSVFEAVVKIPYDPASQQVLGDGSKGGLNVGAVLMLPDGFKIAPPDRIPEEMQEKLGGVYFQSYKEGQDNVVIVGPLPGDQYKEIVFPVLAPDPSQNKGIHFGKYAVHLGANRGRGQVYPTGEPSNNNAFKASTAGTISQISKTEAGGYEVTITSEAGPVVENIPAGPELIVSEGQAIEVGQFLTSNPNVGGFGQKDTEVVLQNPGRIKGLVLFLGGIMLCQILLVIKKKQVETVQAAEMNF",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASSSSLTRSGSVHLDEKWKLSKKDGGASRITRSSSTSSSSFNGKKQGRCAFTRKCARLVKEQRARFYIMRRCVIMLICWRDNYSDS",
    "output": "Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKSSPAELISEAKSSTQNSKMKRAVSVLDFILRLIAVVATLASAIAMGTTDESLPFFTQFIRFRAEYDDLPTLRLFVVASAFASGYLILSLPLSILHITRSSARRTRVILIILDMVMLTSLTAASSAAAAIVYLAHKGNAKANWFAFCQQYDSFCERISGSLIGSFIAIPLFIMLILFSALVLSKR",
    "output": "Regulates membrane-cell wall junctions and localized cell wall deposition. Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAILGLGTDIVEIARIESVIARSGERLARRVLSDNEWAIWKTHHQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKLGVVNMHVTLADERHYACATVIIES",
    "output": "Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MYKPKIICLLLGMLSGLVFAPTFFIPALLTLSYLCYIVQKSENWQEAAKFGYLFGFGHFLSGIYWISIGVSVYIADFWWAIPFALFGLPIVLAFFISASCTLSFFAKNNKYYQFIFCICWVLFEWVRSWIFTGLPWNLIGYAFSFSDILIQTLSIIGIYGLSFIVIYISTSAYPLFRKQFTQLKILLASSVLILSVIVIYGAVRLSNNPTNFTDIKVRLVQPSIPQTEKWNEEEFWHNLMLHINLSENSEPTDLIIWSEAALIVPDDIPQVKSELLQMLNSTNAILITGGISDNKKQGDEFELYSAMYALDKNDHKLFEYHKSHLVPFGEYMPLKKILPFKKLTHGLIDYKEGDGGLVYLEKYNLKIKPLICYESIFPDFVRTNNEIVDVIINITNDAWYGKSSGPYQHFHISRSRAVENGLPMIRVANNGISAIVDPFGRTIEKLNLNEINYTQGLIPKKLNSPTIFSQFGNFTILLLIVFILLINYLLALILDN",
    "output": "Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTARRLINIVPNTSKLDPLKEEDSTHLKQNQPKKFSTKELMLSEYTERKSCSLPLSKSRSGSSASSSTTGSNGKNIGTRRPSSNLDFNFASQDVVKNVLGNNNPHVPTAKCIRPISDDSIGTSSTEIFSSSHSNTTSDSLCTSDISSEEGEIANSKMEDNCFFKSMREADHRSNITPLKKSRPGSILQKTRTASSADKTICSMSTITTCIPSRQNSVSTPKLSRTVGLPGSSNTTNSIAASQTSFISENDSPLKHHCMSTATIQEPKLMPITKTPYVHSNSTSVILPYKTTQLTPSQRYRLRKEQNDQSLRKAIKMKEKFYEDQDVNLELQEGDVDGSLIWNIPMASLSTSSFLTLSKFNRKEMSLDSARGDEEILIQENNCEGKQHSSSALCVDKTFHQVHSTRKHTSNSSNTLKESCLDYKELPPTCIPGISPVSDSQYIQDTMKNLSQIYLHSSEKISKSILSGRSRSVQSLPLEFKEASSQGMEDLMLVSEDKLKAVSHFRPSWLPPKDFKERKLQDKQIYKNIDLASMEELQKNKERDEKAKKNEQNKVKFQHLLDRGITRNSSLSELKKIIWETPLISKVRLQIYSQLLQSDNCLITKCFIESFEEVMQLLNKMDFPKDKEFEIRQLIEHDVQEKVFYKNGTDKQVVSDLMLLLQLKSISQQGLVTGDEMLFYHFLTDQSFGTLKETWEMVNLIQMTCFSEICKEKYDSRILNPRGIVAHLLRKDEFKNEFNGGCLNSNTWWNILQRMDHKLFMWVMDVIIVHNGQNFANYPVKMEIFKDKVWEYYRSKKVIVNYKILVSLTVNVLLNYHFGYDNLKHLSDLDDKHFCIPLYTEDSIEEENLNNIFTKWWLHYYRKLR",
    "output": "With SBE22, is involved in cell wall integrity and polarity processes like bud growth, through the transport of CHS3 and UTR2 to sites of growth."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTSRTAPASPVVHVIGAGLAGSEAAWQIARAGVRVVLHEMRPVRTTEAHKTDGLAELVCSNSFRSDDAANNAVGLLHAEMRRLGSLIMQAADANQVPAGGALAVDRDGFSAAVTKALAEHPLIEICREEIDGLPPQEWTNVVIATGPLTSAPLADAIRGLTDESALAFFDAIAPIVHRDSIDMSVAWFQSRYDKVGPGGTGADYLNCPMTREQYDAFVDALIEGEKVDFKDWEKDTPYFDGCLPIEVMAERGRETLRHGPMKPVGLTNPHNPTVKPYAIVQLRQDNKLGTLYNMVGFQTKLKHGAQLRVFRTIPGLENAEFARLGGLHRNTFLNSPKLLDESLRLRASPRLRFAGQMTGCEGYVESASIGLFAGLAAAADLVGQSLAPPPPTTALGALLGHITGGHIETIDAGPRSFQPMNINFGLFPPLANPPTKGPDGKRLRGPEKSVAKKQALSARALADIDAWIAAHLKLPKAA",
    "output": "Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVIGLSHYLTVSAILFTLGVFGIFLNRKNVIVILMSVELILLSVNINMVAFSHFLNDIVGQVFALFILTVAAAEAAIGLAILVVFYRNRGSIAVEDVNMMKG",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLMSRIAYCRLDGILLLDKPAGISSNSALQIARRLLRAKKGGHTGSLDPLATGLLPLCFGEATKIAGLLLGSTKAYDADVLLGTTTTTDDAEGAVLLTRPVPTLDAEMVDAVIPQLIGRIRQRAPIYSALKQGGEPLYAKARRGEVVNAPVREVEVHAIELLVLATPRLQLRVTCGSGTYIRSLVRDLGEILGCGAHITALRRRWVAPFQIPKMLTLDALEQALSAGRDPDSLLLPLVEGLAGFPALELDAQRLACFRLGQRLRDHSFQTGRVAVFSRDGIPAGLGEVDSEGLLVPQRLFNL",
    "output": "Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQGAEVVQGDQDDQVIMELALNGAYATFIVTNYWESCSQEQEVKQGKLLADLARRLGLHYVVYSGLENIKKLTAGRLAAAHFDGKGEVEEYFRDIGVPMTSVRLPCYFENLLSHFLPQKAPDGKSYLLSLPTGDVPMDGMSVSDLGPVVLSLLKMPEKYVGQNIGLSTCRHTAEEYAALLTKHTRKVVHDAKMTPEDYEKLGFPGARDLANMFRFYALRPDRDIELTLRLNPKALTLDQWLEQHKGDFNLL",
    "output": "Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTEAEQKAAFLGGLVVSFKEQMHTDVLVKPGEEAPPIPTHKAVLAARSKVFRNMLDSDECKTSPEESITLPDLSHDELKSLLEFLYSGNLKAPYNQYRSLYLAADKYDISYLQDVCRNHFIASLSSRNVLDILELASIPCDTILKDAAINHIVKHMEEVVVPMKYETFVQRNPDLSVEITRAYLRETKAKAKDHGAPLNGNTRPRIW",
    "output": "May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNYTILVTGPPYGTQNSSTAFLFCQSLLKTKHILHSVFFYCDGVLNANNMTTPAIDEFNLINAWQGLNKKHQVKLYVCNSAALRRGVIEDEKLFNMNVKKGNLALSFQLSGLIELAKSIKICDRIIQF",
    "output": "Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKKKSPGTLAENRKARHDYNIEDTIEAGIVLQGTEIKSIRRGSANLKDSYAQVKNGEMYLNNMHIAPYEEGNRFNHDPLRSRKLLLHKREIFKLGEQTREIGYSIVPLKLYLKHGHCKVLLGVARGKKKYDKRQALKEKAVKRDVARDMKARY",
    "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MHQKRTAMFQDPQERPRKLPQLCTELQTTIHDIILECVYCKQQLLRREVYDFAFRDLCIVYRDGNPYAVCDKCLKFYSKISEYRHYCYSLYGTTLEQQYNKPLCDLLIRCINCQKPLCPEEKQRHLDKKQRFHNIRGRWTGRCMSCCRSSRTRRETQL",
    "output": "Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT). The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization. Other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis. E6 also inhibits immune response by interacting with host IRF3 and TYK2. These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MELKCLNWFENRGNDSRFLFLKARRADNAVVYLRFVQHFYYVVRADAVADIAQPLAWTRALGPMSVVSIDEIVARSAKIPERQRSEIELCLVASERKLAPPEVFMSDFLNVSWFFVAHDIDPDGCYRVDPALLRDLGSNCFHCDDPGACFAEKIPRFNVTRSGLFLDIECHFEKKFPSVFKNAVSHISFCVVDKDGAERRFTLTNSDMLSDADLEEAARREIPVCLDPADVKFDAEVTLCPEVTLLRVAKRLLEMPLDFVVTFNGHNFDLRYLDSRLSLLTGEHIRFRLPDGTETVNFCVYERTKSSHKGVGGVSSTTFHINNNNGTIYFDLYAFIQRTEKLDSYKLDAISKNAFHCTAVVEDARPDAVRFRGDRSTDADGNAAVFARVLSTGNYVTVDERVCRVLHKRVDEDGFTVDLADPAARAPGDRVTLAFGKDDVSLADMYANYSLDVCLDMARYCLHDACLCLYLWSHYGVETKIAAAASTYLLPQSVVFEYRASTCIKGPLMKLLLENRTVMVRADTKSKFFYEGGRVMAPKQKMHNKHVLIFDYNSLYPNVCIYANLSPETLVGVVVSDNRLDAEVAAVDVRRMFPAPRYIAVPCEPRSPELVAEVAIFDREAKGIIPMLLRSFLDARAKYKKLMKAAETAVDREIYNSMQYTYKITANSVYGLMGFRNSALFSYASAKSCTAIGRTMIAYLERTLDGASVCGTRLSLAAAPDNPLLRDEAFAGRAAELEIDAAVAGERTERVGFRSVYGDTDSVFLEVGASDIAFSRRVGRCLERVINEHVLFANFKVEFEAVYCNLIMQSKKKYTTIKFAVSDGGGSERVSKGTSETRRDVAPFHKLMIRKYKDMLCRALAEEGSGNVGVEILRSLEDELTFEFEARSMPLDWFLLSRTHHKNFKSPDNPNVALVTRYNAANAEAIEIGERYFFAYVCEEGPWRRRIANVKSYERVVDKTFRLDKNERIMYEVYFKRLCTEIVNLLDNKAMCTLFFERLFGSKPVFTG",
    "output": "Catalyzes DNA synthesis. Acquires processivity by associating with a heterodimeric processivity factor comprised of the viral A20 and D4 proteins, thereby forming the DNA polymerase holoenzyme. Displays 3'- to 5' exonuclease activity. Might participate in viral DNA recombination. Does not perform translesion synthesis across an abasic site (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKESYKRDKPHVNIGTIGHVDHGKTTLTAAITSVLAKSGKAAAREFGDIDKAPEERERGITISTAHVEYQTDKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAGTDGPMPQTREHILLARQVNVPALVVFLNKVDIADPELLELVEMELRELLTEYGFPGDDIPIIKGSALNALNGDPEGEKAIMELMDAVDDYIPEPVRDVDKPFLMPVEDVFSISGRGTVGTGRIERGIIKVGNEVEIVGIKPTTKSVVTGIEMFQKTLDEGQAGDNAGLLLRGVDKEALERGMVIAKPGSITPHTKFKAEVYILKKEEGGRHTPFFNGYRPQFYFRTTDVTGSVTLPEGVEMVMPGDNLSVDVELIAPIAMEESLRFAIREGGRTVGAGSVTKIVE",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEIDLGANAFGIDFHPSTNLVAAGLIDGHLHLYRYDSDSSLVRERKVRAHKESCRAVRFIDDGQRIVTASADCSILATDVETGAQVAHLENAHEDAVNTLINVTETTIASGDDKGCVKIWDTRQRSCSHEFNAHEDYISGMTFASDSMKLVVTSGDGTLSVCNLRTSKVQSQSEFSEDELLSVVIMKNGRKVICGTQNGTLLLYSWGFFKDCSDRFVDLAPNSVDALLKLDEDRLITGCDNGIISLVGILPNRIIQPIGSHDYPIEDLALSHDKKFLGSTAHDSMLKLWNLEEILEGSNVNSGNASGAAEDSDSDNDGMDLDNDPSKSSKGSKRKTKSKANTLNATNNFFADL",
    "output": "Required for male and female gametogenesis, seed development, and embryo and endosperm development at early stages. Involved in the establishment of bilateral symmetry in the transition from the globular to the heart embryo stage. May act in the frame of a CRL4 complex . Required for proper vegetative growth and organization of the adult plant body. May play a role in hormonal control of plant development ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAVNTQPIIRLTNVTKSYGEHQVLKNINLDLEAGKFYTLLGPSGCGKTTILRTIAGFTDATSGQVYFDGQVINTLPANQRQVNTVFQDYALFPHMNVAENVAFGLKLHKVPKDEIETRVQKALAMVQLADLGEREISEISGGQQQRVAIARALVMQPKVLLLDEPLSALDAKLRKDMQYELRDLQQRLGITFLFVTHDQEEALAMSDEIFVMNAGEILQGGSPVDIYDEPINHFVANFIGESNIIPGKMLKDFEVEFVGKQFECADAGMQPNEAVEVVLRPEDLDIVAANQGKLVVTVDSQLFRGNYFEIVAYDTDHNEWLVHSTNPAAEGEPIGLTFDPQDIHVMRLNESEAAFDARLEQYEDD",
    "output": "Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQINPTTSGTAVSQLEEKNLGRVAQIIGPVLDVVFPPGKMPNIYNALVVKGQDADGQEIKVTCEVQQLLGNNRVRAVAMSATDGLTRGMDVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLAIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNITESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPGIVGEDHYETAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLEETIRGFKLILSGELDSLPEQAFYLVGNIDEATAKAINLEVESKLKK",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSFSDQNLIWIDLEMTGLDPEMHKIIEMATIVTDSELNILAEGPVIAIHQPESELAKMDEWCTTTHTASGLVARVRQSQVSEEEAIDQTLAFLKQWVPEGKSPICGNSIGQDRRFLYKHMPRLEAYFHYRYIDVSTIKELTRRWQPEVLKEFSKTGSHLALDDIRESIAELQFYRKAVFKI",
    "output": "3'-to-5' exoribonuclease specific for small oligoribonucleotides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTKEKELHCSFCGKEQKEVDKLIAGTSGYICNECIELCHDMLANADDIEEIDEEFQEEEPKLPTPHEIRAHLDDYVIGQDYAKKVLAVAVYNHYKRLRSEKNTSEVELGKSNILLIGPTGSGKTLLAQTLARMLNVPFAMADATTLTEAGYVGEDVENVLQKLLQNCDYDIEKAQQGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKLVEGTVASIPPQGGRKHPQQEMLRVDTSKILFICGGAFAGLDKIIEKRTNTGGKGIGFGADVRIDEEKVSLTELFKQVEPDDLMKFGLIPEFIGRLPVIAPLSELDEEALVKILTEPKNALTKQYQVLFSLENIELEFTQEALIAMAKKALARKTGARGLRSIVETLLLDTMYDLPSIENLQKVIVEEETVTENKAPVLKFNS",
    "output": "ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSEIIESTVAFLIGLLKASWTRTAWHFAVLSFVYVIARSIYRVWFHPLSSYPGPKLAALTQLWYARHWMGGRYPFAIEEAHRRYGEVVRIAPNELSFNTAQSFNEIYGHTTKDHKPFIKGTFYEHYQPEPGIVAERNPEKHRETRKLLAHGFSARALKAQESIIAQYSDLFLAQVKKLAKSHFWIDTIHDAGILVTLFEIGRRLPLLWPLILFSLPNGIKKKFDLFLKYSRDLVRTRVARQNTLTREDFFARLLADKSHSQSEEWLLAQANVLVIAGSDTTATALTTLIYYLAAHQDKLWHLQQELRETFDEASDMTSEKLQGMLYLNAVIEEGLRICPPTAFGLPRISPGAMVDGRLIPKGTVVSTSSWTTAHREDYFHDARGFHPERWLPAGHALWNAKFQHDHLSASKPFSLGPRGCLGVNLAYMEMRITLAKLAWKFDWELVNADQLDWESELRFEGFWKLPVPRVRFYCIHV",
    "output": "Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of oxaleimides, cytotoxic compounds containing an unusual disubstituted succinimide moiety . The first step of the pathway is provided by the HR-PKS poxF that serves in a new mode of collaborative biosynthesis with the PKS-NRPS poxE, by providing the olefin containing amino acid substrate via the synthesis of an ACP-bound dec-4-enoate . The cytochrome P450 monooxygenase poxM-catalyzed oxidation at the alpha-position creates the enzyme-bound 2-hydroxydec-4-enoyl-ACP thioester, which may be prone to spontaneous hydrolysis to yield 2-hydroxydec-4-enoic acid due to increased electrophilicity of the carbonyl . 2-hydroxydec-4-enoic acid can then be further oxidized by poxM to yield the alpha-ketoacid 2-oxodec-4-enoicacid, which is reductively aminated by the aminotransferase poxL to yield (S,E)-2-aminodec-4-enoic acid . The Hybrid PKS-NRPS synthetase poxE then performs condensation between the octaketide product of its PKS modules and the amino group of (S,E)-2-aminodec-4-enoic acid which is activated and incorporated by the adenylation domain . The resulting aminoacyl product can be cyclized by the Diels-Alderase PoxQ and reductively released by the reductive (R) domain of poxE to yield an aldehyde intermediate  (Probable). The released aldehyde is then substrate for a Knoevenagel condensation by the hydrolyase poxO followed by an oxidation at the 5-position of the pyrrolidone ring . The presence of the olefin from the amino acid building block allows for migration of the substituted allyl group to occur . This allylic transposition reaction takes place in a conjugate addition, semipinacol-like fashion to yield a succinimide intermediate . Iterative two-electron oxidations of the C7 methyl of the succinimide intermediate to the carboxylic acid can be catalyzed by one of two remaining cytochrome P450 monooxygenasess poxC or poxD to yield oxaleimide A . Subsequent oxidation yields the maleimide scaffold oxaleimide I . Both oxaleimide A and oxaleimide I can undergo oxidative modifications in the decalin ring to yield the series of products oxaleimides B to H ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIDDTLLESEERMTQSVEYAREDLTTIRTGRANPSMFNGVQAEYYGVMTPITQMATISVPEPRMLLIKPYEPSIMNAIENAIRNSDLGVNPTNDGQVLRVTVPQLTEERRKEMVRLAKSKGEDARIAIRNIRRKGMDELKRIQKDGEAGEDEVQAAEKELDKTTHEYVSQVDKLIEAKEKELMEV",
    "output": "Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNPAHLLVLPAVCVSFLGASIIPPQSLNLIQFKDMIRCTIPCERTWGEYADYGCYCGKGGSGRPVDALDRCCYVHDNCYGEAQKRNCNPYMKSYSFKCAKRTLFCYDAPGSCARFVCDCDRTAALCFGDSEYIGRHKNIDTKRHCQ",
    "output": "Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTTALDQLKQYTTVVADTGDFQQLAQYKPQDATTNPSLVLKAVQKDEYKPLLEKTVRDHASKPVGSIIDNLLIAFGTEILKIVPGRVSTEVDARLSFDTKASIDKAHELIKMYDAQGIGRERVLIKLASTWEGIRAAEVLQKDGIKCNMTLLFSLAQAVAAAEAGAQLISPFVGRIYDWYKKNAGSNWDEARDGGANDPGVQSVRRIYAYYKKFGYPTEVMGASFRTTSQILELAGCDLLTISPDLLQKLHDSNDRIERKLSPEASRNADIERVPTDEASFRFLVNDDAMATEKLSEGIRVFAADAIKLEKVIEALR",
    "output": "Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVASKPFAERYFPNGVTRSSLLKAPAVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELESGELINLTPGLLQRRMLYWHRFAPESRMMRKVTDALLEYGHKVLRQD",
    "output": "Controls the transcription of genes involved in arginine and lysine metabolism."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MALCNGDSKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHKKSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGTSKVLVLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLKPEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPGNEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE",
    "output": "Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGPSGTAHRMRAPLSWLLLLLLSLQVAVPAGALAETLLDAPGARGASSNPPSPASVVAPGTTPFEESRLPVFTLDYPHVQIPFEITLWILLASLAKIGFHLYHKLPTIVPESCLLIMVGLLLGGIIFGVDEKSPPAMKTDVFFLYLLPPIVLDAGYFMPTRPFFENLGTIFWYAVVGTLWNSIGIGLSLFGICQIEAFGLSDITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYNLFKSFCQMKTIQTVDVFAGIANFFVVGIGGVLIGILLGFIAAFTTRFTHNIRVIEPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFVCFTLAFCLIWRALGVFVLTQVINWFRTIPLTFKDQFIIAYGGLRGAICFALVFLLPATVFPRKKLFITAAIVVIFFTVFILGITIRPLVEFLDVKRSNKKQQAVSEEIHCRFFDHVKTGIEDVCGHWGHNFWRDKFKKFDDKYLRKLLIRENQPKSSIVSLYKKLEIKHAIEMAETGMISTVPSFASLNDCREEKIRKLTPGEMDEIREILSRNLYQIRQRTLSYNRHNLTADTSERQAKEILIRRRHSLRESLRKDNSLNRERRASTSTSRYLSLPKNTKLPEKLQKKNKVSNADGNSSDSDMDGTTVLNLQPRARRFLPDQFSKKASPAYKMEWKNEVDVGSARAPPSVTPAPRSKEGGTQTPGVLRQPLLSKDQRFGRGREDSLTEDVPPKPPPRLVRRASEPGNRKGRLGNEKP",
    "output": "Plasma membrane Na(+)/H(+) antiporter. Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+) . Major apical Na(+)/H(+) exchanger in the base of the colonic crypt. Controls in the colonic crypt intracellular pH (pHi) to direct colonic epithelial cell differentiation into the absorptive enterocyte lineage at the expense of the secretory lineage (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTIVLGRVPKEENDLFDTMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFALIGFMLRQFELARSVQLRPYNAISFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSAIGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL",
    "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSINATARALLLTEFVSAFFLTMRYFFQPKATINYPFEKNPISPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIEAGPRRNDGTRRTVRYDIDMVKCIYCGLCQEACPVDAIVEGPNFEFATETREELYYDKAKLLANGDRWEREIAKAIELDAPYR",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADVPSMDALVALLRRLPGIGPRSAQRISYELLVRKRDLMPQLAAAFQQAHAVVRFCERCNNLSEAPLCAVCRSEHRDRSILCVVESPADLRAIEDTGVFVGEFFVLMGHLSPLDGIGPEALHIDRLSARLGETDLQEVIFATNPTLEGEATAQFLAGLVPDGVTISRIARGVPVGGELEYVDRSTLGRALHGRRLLDE",
    "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKICLLCVGRLSIGYLREGAADFEARLQRYLPVRIVELKEEKSGKNDAEYIRRQEGRRILEKIPAGSFVIALDERGRSVSSEKLAALLERHMMESTPELTLIIGGAYGLCDEVKQRADMLMSLSEMTLTHQMARLVLLEQLYRGFTIVRNEPYHNR",
    "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSKENEVLLNEDIRAREVRCVGDDGTAYGVISRDEALEISNKLGLDLVLIAPDAKPPVCKIMDYGKFRYQQEKKQKEAKKKQKTIEIKEIKLSVKIAQNDINYKVKHASEFLQDGKHVKFRVFLKGREMSTPEAGVAMLEKVWEMIKDEADRDKEPIIEGRYVNMLVTPKKG",
    "output": "IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDQREILQQLLKEAQKKKLNSEEFASEFLKLKRQSTKYKADKIYPTTVAQRPKNIKKNRYKDILPYDHSLVELSLLTSDEDSSYINASFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYRILVIVMACMEFEMGKKKCERYWAEPGETQLQFGPFSISCEAEKKKSDYKIRTLKAKFNNETRIIYQFHYKNWPDHDVPSSIDPILQLIWDMRCYQEDDCVPICIHCSAGCGRTGVICAVDYTWMLLKDGIIPKNFSVFNLIQEMRTQRPSLVQTQEQYELVYSAVLELFKRHMDVISDNHLGREIQAQCSIPEQSLTVEADSCPLDLPKNAMRDVKTTNQHSKQGAEAESTGGSSLGLRTSTMNAEEELVLHSAKSSPSFNCLELNCGCNNKAVITRNGQARASPVVGEPLQKYQSLDFGSMLFGSCPSALPINTADRYHNSKGPVKRTKSTPFELIQQRKTNDLAVGDGFSCLESQLHEHYSLRELQVQRVAHVSSEELNYSLPGACDASCVPRHSPGALRVHLYTSLAEDPYFSSSPPNSADSKMSFDLPEKQDGATSPGALLPASSTTSFFYSNPHDSLVMNTLTSFSPPLNQETAVEAPSRRTDDEIPPPLPERTPESFIVVEEAGEPSPRVTESLPLVVTFGASPECSGTSEMKSHDSVGFTPSKNVKLRSPKSDRHQDGSPPPPLPERTLESFFLADEDCIQAQAVQTSSTSYPETTENSTSSKQTLRTPGKSFTRSKSLKIFRNMKKSVCNSSSPSKPTERVQPKNSSSFLNFGFGNRFSKPKGPRNPPSAWNM",
    "output": "Acts as negative regulator of T-cell receptor (TCR) signaling by direct dephosphorylation of the Src family kinases LCK and FYN, ITAMs of the TCRz/CD3 complex, as well as ZAP70, VAV, VCP and other key signaling molecules (By similarity). Associates with and probably dephosphorylates CBL (By similarity). Dephosphorylates LCK at its activating 'Tyr-394' residue (By similarity). Dephosphorylates ZAP70 at its activating 'Tyr-492' residue (By similarity). Dephosphorylates the immune system activator SKAP2 (By similarity). Positively regulates toll-like receptor (TLR)-induced type 1 interferon production . Promotes host antiviral responses mediated by type 1 interferon . Regulates NOD2-induced pro-inflammatory cytokine secretion and autophagy . Acts as an activator of NLRP3 inflammasome assembly by mediating dephosphorylation of 'Tyr-861' of NLRP3 . Dephosphorylates phospho-anandamide (p-AEA), an endocannabinoid to anandamide (also called N-arachidonoylethanolamide) ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIGRISGLLLEKFPPLVLVDVQGVGYEIDVPMSTFYNLPAVGTQITLHTHFVVREDAHLLFGFATEGERQAFRQLVKISGVGARTALALLSGLSVADLHQTVSNQDPARLIRIPGIGKKTAERLLLELRDKLDLGVSAIPGAAGARRPSTMGSDVLNALLSLGYNDREANWAVSQLSVDLSVSDGIRQALKFLSKEK",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTARKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAHDLKVGLFQDTSAF",
    "output": "Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKSSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRETLLTMAERARAASIPDATERVANEVSRAARA",
    "output": "Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQFTIFTHLTMALSYAVPILIAVAFLTLVERKVLSYMQARKGPNIVGPFGLLQPVADGVKLFIKEPVRPTTSSPILFIATPILALLLAITIWIPLPLPFSLTDLNLGLLFLLSMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVIMLSGNYTLNTLATTQEPLYLIFSTWPLAMMWYISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYANIMLMNTLTAILFLNPSSLNLPSELFPLILATKTLLLSSGFLWVRASYPRFRYDQLMHLLWKNFLPLTLALCLWHTSLPISYAGIPPHL",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA",
    "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate . CoA is not a substrate for the enzyme ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQIPKPNNSTWTDDQWEAIVSEGQDILVAAAAGSGKTAVLVERLIRKMTRPEHPVDVDRLLVVTFTNASAAEMKHRITEALEKELAKNPGSLHMRRQLSLMNRANISTLHSFCLQVLRTFYYEIDLDPGFRLADQTEGELLGDEVLDELFEDEYKAGKPSFFELVDRYTSDRHDLDLQWLVKRIYDFSRSHPSPEQWMRAFLSLYDVDAQTKVEELPFYPYIKEDLSLVLRSCQELLERALSLSKEPGGPAPRAENFIDDLEQVNELIRHQDDFEKLYELLPNVNFKRLKTCKGDEYDPVLLEKATDARNQAKKQLEKLKDEYFMRSPAQHLKSLAEMKPIVETLVELVIQFGERFERAKQEKSIVDFSDLEHYCLRILAEQDAEGHLIETEAAKYYQQQFEEVLVDEYQDTNLVQETILKLVSKGEHSSEGNLFMVGDVKQSIYRFRLAEPMLFLNKYKHFQPDGKETGKRIDLNKNFRSRSDVLDSTNFLFKQLMGETVGEIEYDEQAELKLGASYPESKDTTTEMLLVHLDQQEAETGEEREELETVQFEARIIAKKIKELVEQPFQVYDAKQQMTRNLQYRDIVILLRSMPWAPQMMEELKKQGIPVYANLSSGYFEATEVSVILSLLKVIDNPYQDIPLAAVLRSPLVHLDENELALIRTSDKKGTYYDAVKAFMSVTHSDHPTCKKLERFFQLLRKWRDFSINHSVAELIWEVYRDTQYLDYVGGMPGGKQRQANLRALYDRAKQYEKAAFRGLFRFLRFIERMQERGDDLGAAKTFSETEDVVRMMTIHSSKGLEFPVVFTVGLGRNFNMMDLNQSYLLDKELGFGSKYIHPELRISYATLPLVAMKKKMRKELLSEELRVLYVALTRAKEKLFLVGSVKNQVKALSKWQNAATGEEWLLPDFERYQSKTYLDFIGPALIRHQAMSSVLEETGDVVLSHPSTFTISFTQASDLLKEDMSLEKKEQDEIVQALMDGLPVEGYGDADEKVAERLSWKYPYLAASQVGTKQSVSEIKRMKEIQDEYSVPSSIRKARATLYDRPAFMKKKTLTAAEQGTAMHTVMQHIPLPSEEPYDESRIGHLLDSLQQRDLLTDEQVQSINQEGIAAFFSTSIGQKLLKADWVKREVSFSMVLPVKEVYSHIDTEGEPVLIQGMIDCLFETDGKLYLLDYKTDRVQGRYTGGIDAAVPILKKRYETQIALYAKAVERLTNRTLEEKILYFFDGNVEISL",
    "output": "The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTTESLETLVEQLSGLTVLELSQLKKLLEEKWDVTAAAPVVAVAGAAAAGDAPASAEPTEFAVILEDVPSDKKIGVLKVVREVTGLALKEAKEMTEGLPKTVKEKTSKSDAEDTVKKLQEAGAKAVAKGL",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRELPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGGTLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSHLLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGSTIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD",
    "output": "Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQRVQPSAARVKSQKKEKAPPDVPDVILDGERKTRYEKGKFLGKGGFAHCYELRNKSTGELFAGKVVPKALLIKQYQRDKMAQEVQIHRNLQHRNVVKLYHFFEDKSNVYITLELCPRRSLMELHKRRKAVTEPEARYFTYQIVEGVLYLHNLKIVHRDLKLGNLFLNDELQVKIGDFGLATTCDNDERKKTLCGTPNYIAPEVLNKIGHSFEVDLWAIGCILYILLFGHPPFESKSLEETYSRIKNNNYVIPTSASAAASQLIRVLLDPVPSRRPNARAVCRDHFFKSGFMPARLPVSCLTMVPHLNDDEYAEENVSPSGTIDQRGPHQAGRSGLSAIPAHLVSRNSERQQTHRMEAYRQPTDCYLSNLLAQVNDLLATPTADIDDAEAALDSYQSPEALPVFWISKWVDYSDKYGIGYQLCDNSVGVLFNDNSRIMLDTAGTQLTYIEKTEKEHYFDMESAIPSGLQKKMTLLKYFRSYMNDHLLQAGQQVTRKVGDDLARLPTLRVWFRTKSAIVLHLSNGTVQINFFNDHIKMVLCPLMQAVTFIDENKRMFTYKFSHLAENGCPEKFLHRIQYAKCMIQRLVEEHTKEETKHNAPAANAVRLPSTSSNVRLESAADIQPAYPSSSRR",
    "output": "Serine/threonine-protein kinase which plays a role, during oogenesis, in chromosome pairing and synapsis, by facilitating the recruitment and attachment of meiotic chromosomes to the nuclear envelope during prophase . Promotes the localization of brc-1 to the short arm of homologous chromosomes during meiotic prophase I . Regulates the formation of sun-1 patches along the nuclear envelope . Promotes meiotic nuclei apoptosis in response to chromosomal asynapsis . Plays a redundant role with plk-1 in the establishment of cell polarity downstream of mex-5 and mex-6 during the first embryonic cell divisions . Plays a role in nicotinic acetylcholine receptor-mediated sensitivity to nicotine but not levamisole . Regulates motility ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSQPLFTATVSAVGGREGKVISSDRVLELDVAMPGTPRAKKLEKATNPEQLFAAGYAACFDSALQLVARTERVKVETEVTANVSLLKDEADQGYKLGVTLQVKGEGVSASELEALVKKAHGVCPYSKATSGNIDVTLEVAE",
    "output": "Involved in organic hydroperoxide resistance."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSPIIDALVPMVVEQTSRGERSYDIYSRLLKERVIFLTGQVEDHMANLVVAQLLFLESENPDKDIFLYINSPGGSVTAGMSIYDTMQFIKPNVSTVCMGQACSMGAFLLAGGAPGKRYVLPNSRVMIHQPLGGFQGQASDIQIHAQEILTIKTKLNKLLAEHTGQPLEVIERDTDRDNFMSADQAVEYGLVDAVLTHRSA",
    "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKKGAGATRGISPVRPTRAIPIGAYLTVADNSGAKVIQVIGVVEYHGTRRRLASAGVGDMVVATVKKGRPDMRHQVVRAVIIRQRKEYRRLDGMRVKFEDNAAVIVTPEGVPRGTEIRGPVAREAAEKWVRIGSIASIIV",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH",
    "output": "Could be involved in insertion of integral membrane proteins into the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGDAEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFVLEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDIILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSRCEEGFVTGGHVLRLFHGHMDECLTISPADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRVRHVTTGQYLALTEDQGLVVVDASKAHTKATSFCFRISKEKLDVAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIHSTNGLYNQFIKSLDSFSGKPRGSGPPAGTALPIEGVILSLQDLIIYFEPPSEDLQHEEKQSKLRSLRNRQSLFQEEGMLSMVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYELLASLIRGNRSNCALFSTNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGTTQYSKWYFEVMVDEVTPFLTAQATHLRVGWALTEGYTPYPGAGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVISCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLEPIKEYRREGPRGPHLVGPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVGQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVENQSRCDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQPGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKGLPQFEPVPLEHPHYEVSRVDGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAGATPLAPPGLQPPAEDEARAAEPDPDYENLRRSAGGWSEAENGKEGTAKEGAPGGTPQAGGEAQPARAENEKDATTEKNKKRGFLFKAKKVAMMTQPPATPTLPRLPHDVVPADNRDDPEIILNTTTYYYSVRVFAGQEPSCVWAGWVTPDYHQHDMSFDLSKVRVVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFQSERKNPAPQCPPRLEMQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQEPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRSTENGHPRHGLPGVGVTTSLRPPHHFSPPCFVAALPAAGAAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYGLLIKAFSMTAAETARRTREFRSPPQEQINMLLQFKDGTDEEDCPLPEEIRQDLLDFHQDLLAHCGIQLDGEEEEPEEETTLGSRLMSLLEKVRLVKKKEEKPEEERSAEESKPRSLQELVSHMVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLVAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGIRRDRRREHFGEEPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLEDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMSLCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDPELYRMAMPCLCAIAGALPPDYVDASYSSKAEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEEEKTEKKKTRKISQSAQTYDPREGYNPQPPDLSAVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRGLKDMELDSSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTKNTYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLERLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPSALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLQSHFIPTIGRLRKRAGKVVSEEEQLRLEAKAEAQEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAQWLTEPNPSAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKSKMAKAGDIQSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLITLAKTRYALKDTDEEVREFLHNNLHLQGKVEGSPSLRWQMALYRGVPGREEDADDPEKIVRRVQEVSAVLYYLDQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEEGGENGEAEEEVEVSFEEKQMEKQRLLYQQARLHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFSGPEIQFLLSCSEADENEMINCEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLHNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPEGEPETDEDEGAGAAEAGAEGAEEGAAGLEGTAATAAAGATARVVAAAGRALRGLSYRSLRRRVRRLRRLTAREAATAVAALLWAAVTRAGAAGAGAAAGALGLLWGSLFGGGLVEGAKKVTVTELLAGMPDPTSDEVHGEQPAGPGGDADGEGASEGAGDAAEGAGDEEEAVHEAGPGGADGAVAVTDGGPFRPEGAGGLGDMGDTTPAEPPTPEGSPILKRKLGVDGVEEELPPEPEPEPEPELEPEKADAENGEKEEVPEPTPEPPKKQAPPSPPPKKEEAGGEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDMEGSAAGDVSGAGSGGSSGWGLGAGEEAEGDEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIYGRERIAELLGMDLATLEITAHNERKPNPPPGLLTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS",
    "output": "Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules . Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm . Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSQFNQNNKQIDVMGIRKILPHRYPFALLDKIVDWSVEDRTIVAQKNVTINEDFFNGHFPDFPVMPGVLIVEAMAQATAILGELMAETLFAHVVEKAGGGRRTFMLAGIDKVRVKRPVVPGDVLVIESRMVKQKNIICTAESVAKVDGQIVCSAELMAAYKDY",
    "output": "Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVRILRWFIRLYQIAISPLLGPRCRYIPTCSQYALEALQTHGAIKGVWLSSKRICRCHPWGGSGYDPVPLKAIRFISFHQIDSQTHHVAVPFRDRLMKQNLSNHLG",
    "output": "Could be involved in insertion of integral membrane proteins into the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTTFSSFPSIFVPLVGLVFPAIAMASLSLYVQKTKIF",
    "output": "May help in the organization of the PsaL subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKPTTIASLQKCKQEKKRFATITAYDYSFAKLFAEEGLNVMLVGDSLGMTVQGHESTLPVTVEDIAYHTTAVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVKMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEASDRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH",
    "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLLIVGLGNPGAKYQGNRHNIGFMAVDAIHRRHSFSPWAKKFRAEISEGELGGQKVLLIKPQTFMNLSGESVGEAMRFYKLEPSDLVVIYDELDLPAAKARLKTGGGHGGHNGIKSIDAHCGREYRRLRLGIGHPGVKELVQNHVLGDFAKVDRDWLEPLFDALADNADMLVRGEDSQLMNKIALALGGKTEEPAPKPEKKTVAKSHIHQARNHNQPRMPESGPMAEMLKRMFGKKDD",
    "output": "The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNTEIPDLEKQQIDHNSGSDDPQPIHDDMAPVSRIRSSGPNHEYIHIADQKFHRDDFYRAFGGTLNPGGAPQPSRKFGNPAPLGLSAFALTTLVFSLCTVQARGVPNPSIAVGLALFYGGVCQFAAGMWEFVQENTFGAAALTSYGGFWMSWAAIEMNAFGIKDSYNDPIEVQNAVGIYLFGWFIFTLMLTLCTLKSTVAFFGLFFMLMMTFLVLACANVTQHHGTAIGGGWLGIITAFFGFYNAYAGLANPGNSYIVPVPLDMPFVKKD",
    "output": "Plays a role in the adaptation of cell metabolism to the utilization of acetic acid, possibly by inhibiting an anion-transporting ATPase and affecting the plasma membrane H(+)-ATPase. May be indirectly involved in the repression of genes encoding glyoxylate cycle enzymes."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLDIQLLRKDLDGVAKRLADRGYPLDVAAFSALEAERRAIQTRTEELQARRNSLSKQIGAMKGRGEDTSAVMAEVGGIGDEMKASAVKLDEIQARLSELMLEMPNVPHESVPVGRDETENVEVRRWGAPRQFDFDVKDHVDVGTPLGLDFETGAKLSGARFTVLRGPIARLHRALAQFMLDTHTQQHGYSETYTPYIVNPDVLYGTGQLPKFAEDMFRVEKGGAENTVTQYLISTSEISLTNTVRDSIVEASALPIKLTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVAPEASYAALDEMVGHAEAILQKLELPYRVVALCTGDMGFSAAKTFDLEVWLPAQNTYREISSCSNTESFQARRMQARFRNAQGKPELVHTLNGSGLAVGRTLVAVLENYQNADGSVTVPVALRPYMGGVERIDAPSSAA",
    "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFPGSVIRKLSHSEEVFAQYEVFTSMTIQLRGVIDVDALSDAFDALLETHPVLASHLEQSSDGGWNLVADDLLHSGICVIDGTAATNGSPSGNAELRLDQSVSLLHLQLILREGGAELTLYLHHCMADGHHGAVLVDELFSRYTDAVTTGDPGPITPQPTPLSMEAVLAQRGIRKQGLSGAERFMSVMYAYEIPATETPAVLAHPGLPQAVPVTRLWLSKQQTSDLMAFGREHRLSLNAVVAAAILLTEWQLRNTPHVPIPYVYPVDLRFVLAPPVAPTEATNLLGAASYLAEIGPNTDIVDLASDIVATLRADLANGVIQQSGLHFGTAFEGTPPGLPPLVFCTDATSFPTMRTPPGLEIEDIKGQFYCSISVPLDLYSCAVYAGQLIIEHHGHIAEPGKSLEAIRSLLCTVPSEYGWIME",
    "output": "Catalyzes diesterification of phthiocerol, phthiodiolone, and phenolphthiocerol with mycocerosic acids, the final step in the phthiocerol, phthiodiolone and phenolphthiocerol dimycocerosate esters (PDIM) synthesis. Can directly transfer the mycocerosate bound to the mycocerosic acid synthase (mas) onto the substrate alcohols. Is also able to catalyze acyl transfer using various nucleophiles as acceptors and several acyl-CoA thioesters as donors in vitro; preference is observed for saturated medium chain alcohols and long chain acyl-CoA thioesters."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSFPSSAASPARSEQAVPEGAAKEPMVTFEGVTKTFGGADGKPGFAALAGIDYTVPKGSITCIIGRSGAGKSTLIRLANGLEKPSTGRVVVDGVDVAALDEKSLRTLRRSVGMIFQHFNLLSSRTAFDNVALPLEIAGLGKKEIEARVAPLLDLVGLSDKAKRYPAELSGGQKQRVGIARALATQPKLLLSDEATSALDPETTQSILELLKRINAELGLTVLLITHEMEVVKTIASQVAVIDRGLIVEEGTTFDIFTAPKHETTRSLLSSSVGVKLPHWVTSGLKQEATDGDRVLVRLVFFGETAFQPLTARLVAEIGPDVNILAGTIEEISGQPFGSLVVSYPASAEVTARANRFYAETGLHTEVLGYVA",
    "output": "Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPSPTKAAEAATKATATSDCSCSAASVEQRAPSNAANPSSSLATSGKIGGKTQDQTAAINKQKEFAVPNETSDSGFISGPQSSQIFSEEIVPDSEEQDKDQQESAPQKEQPVVLDSGIIDEEEDQEEQEKEEEHQDTTTATADSMRLKHSADTGIPQWTVESHLVSRGEQLNNLGQSSSTQITGRSKVQSSTASTANANPSGSGATSSAPPSSINIMNAWEQFYQQNDDGDTPLHLACISGSVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPNIMRILLLAGAEPTVRDRHGNTALHLSCIAGEKQCVRALTEKFGATEIHEAHRQYGHRSNDKAVSSLSYACLPADLEIRNYDGERCVHLAAEAGHIDILRILVSHGADINAREGKSGRTPLHIAIEGCNEDLANFLLDECEKLNLETATYAGLTAYQFACIMNKSRMQNILEKRGAETVTPPDSDYDSSDIEDLDDTKMYDRFGDPRYFVSYNGGNPMTVA",
    "output": "Involved in the formation of the dorsoventral pattern. It inhibits nuclear translocation of the dorsal morphogen in the dorsal region of the embryo. Acts as a negative regulator of the NF-kappa-B (rel) signaling pathway. Cact is degraded by IKKbeta, this is essential for NF-kappa-B (rel) activation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEHYISLLVKSIFIENMALSFFLGMCTFLAVSKKVKTSFGLGVAVVVVLTIAVPVNNLVYTYLLKENALVAGVDLTFLSFITFIGVIAALVQILEMILDRFFPPLYNALGIFLPLITVNCAIFGGVSFMVQRDYNFAESVVYGFGSGIGWMLAIVALAGIREKMKYSDVPPGLRGLGITFITVGLMALGFMSFSGVQL",
    "output": "NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGSEAPIAIELDHDQVMNMQAKAEFYSEVLTLVVDGKEVKVKAQAVQRHAYKPKLTHIDFVRA",
    "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDHILALVLALLPLSLCVALPGALDAMDVEKMKSKVTWKAQGLVARIDKHFPDRGLRFDTDKVEGSTSVVASLESYNNLISDRFGGVSQIKTEISSLAGYLNHWREGNCQEQQPKVWPRRNIFNHTVSLEALMRVREFLKLLQKNVDLLERC",
    "output": "May function as part of a signaling pathway that acts to regulate the size of the body fat depot."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "LKCKKLVPLFSKTCPPGKNLCYKMFMVAAPKVPVKRGCINVCPKSSLLVKYVCCNTDKCN",
    "output": "Shows cytolytic activity on many different cells by forming pore in lipid membranes. In vivo, increases heart rate or kills the animal by cardiac arrest. In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEAKAVARTIRIAPRKVRLVLDLIRGKNAAEAIAILKLTNKASSPVIEKVLMSALANAEHNYDMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSDGKEEAKEA",
    "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPVEIDMIVGKDREGFFTNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF",
    "output": "Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MMDKRVVAVAAVLWNVQMLFAAGEVIVPEGYASYYAESFNGRPTASGEIFDMNAYTAAHRTLPFGTVVELTNLDNGKKVIVRINDRGPYAANREIDVSKAAAVALDMLNAGVARVSIHKADPNAHASQQRNDRQTSPGVLPQDSFGVPPTAPTSSAPVMYADPHNPPPAPVGRRAGTPGVPGVANTTDVPASEYGAPPVAYAAPGSTPSRVPYGTAVPGSAAPNSHAQPVPSSSSYAAAAPLPYAAGGGKVSGMKSVYTPTHSGETRGVLWRIQLGAFVREENALRLVVKCARRALILHMSEQSTRCAWCCRGYAPRT",
    "output": "Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFFVTPAYAEEAPAAATGTDAHAAPAAGEVHTETGVAEGEHARGPFPPFDSTTYASQLLWLVITFGVFYLLMQKVIAPRIGAILDQRHKRISQDLEEAGRLKAEADAAVQTYEGELAAARAKSHAIGSAARDAAKVKAEEDRRTVEASLSEKIKAAEARIADIKAKAFADVGTIAEETAAAVVEQLIGSTAAQADVAAAVAAAKKEV",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "RIRARYPIIAAHLAPGSESRFDFQKYVNRSLEDDFKVVVGISPILWFFAVLFLLSNTHGWVAYLWLPFIPLIIILVVGTKLQVIITQLGLSIQDRGDVVKGAPVVQPGDDLFWFGRPRLVLFLIHFCLFQNAFQLAFFIWSVYEFGIKTCFHEKTEDIVRASGLVPNRDTSATQTTELSKGKLMMADTCLPTEDLVGMVVTAAHSGKRFFVDSIRYD",
    "output": "May be involved in modulation of pathogen defense and leaf cell death."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAAVTFASAITNAITSKPALTGMVQFGSFPPMPLRSTTVTTVATSVAQPKLYTVQFGSLDPVVVKSGAGSLAKATRQQPNVEIDVSLSEAAALEVAKPRSNAVLRMHEEANKERALFLDWEASLKRSSYGIAEDEKVVMTTHGVSKIVPRSSRAMKLKRARERRRAQQPIILKWEPKLSGISIGGGLSASVIEAEEVRTKWPLHKTPSMKKRTVHRICKMNDQGVDMLTRSLVKIFKTKSANIEYIGKKSIKVDFIRKERTKFARIQVAHLLGKRAQRDLLTGMEENHFIDILSKYSGNKTTINPGVVCAGWSGIVVGNGILTQKRSRSPSEAFVIRGEHEGKLYDARIKVTRTMSHKIVHFSAAGANFWKGFDRCFLAYRSDNREHTCYSGLDVTECGEVAALMCLAMFPCGKITCPDCVTDSELSQGQASGPSMKHRLTQLRDVIKSSYPRFKHAVQILDRYEQSLSSANENYQDFAEIQSISDGVEKAAFPHVNKLNAILIKGATVTGEEFSQATKHLLEIARYLKNRTENIEKGSLKSFRNKISQKAHINPTLMCDNQLDRNGNFIWGERGYHAKRFFSNYFEIIDPKKGYTQYETRAVPNGSRKLAIGKLIVPTNFEVLREQMKGEPVEPYPVTVECVSKLQGDFVHACCCVTTESGDPVLSEIKMPTKHHLVIGNSGDPKYIDLPEIEENKMYIAKEGYCYINIFLAMLVNVKESQAKEFTKVVRDKLVGELGKWPTLLDVATACYFLKVFYPDVANAELPRMLVDHKTKIIHVVDSYGSLSTGYHVLKTNTVEQLIKFTRCNLESSLKHYRVGGTEWEDTHGSSNIDNPQWCIKRLIKGVYKPKQLKEDMLANPFLPLYALLSPGVILAFYNSGSLEYLMNHYIRVDSNVAVLLVVLKSLAKKVSTSQSVLAQLQIIERSLPELIEAKANVNGPDDAATRACNRFMGMLLHMAEPNWELADGGYTILRDHSISILEKKLSTNLGRSMERVKLVGALCYKILLVKASNLYTERFANEKRSRFRRQIQRVSHVILRTE",
    "output": "[Helper component proteinase]: Cysteine protease that cleaves a Gly-Gly dipeptide at its own C-terminus (By similarity). Required for aphid transmission and also has proteolytic activity (By similarity). Interacts with virions and aphid stylets (By similarity). Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity). May have RNA-binding activity (By similarity).; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MMFRVTSVGCLLLVIVFLNLVVPTSACRAEGTYCENDSQCCLNECCWGGCGHPCRHPGKRSKLQEFFRQR",
    "output": "Modulator of potassium channels, specifically up-modulates the calcium and voltage-gated BK channels, has no effect on single channel conductance, but increases the open probability of BK channels."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTVHLIADSATDLPRSYFEEKGIGFIPLRVSLGDKEFEDAVTIHADQIFEAMQNGETPKTSQASPQTIKNVFLQYAETGDPALYIAFSSGLSGTYQTAVMIANEVKEEFPDFDLRVIDSKCASLGYGLAVRHAADLCINGNTIQEIETSVKNFCSQLEHIFTVDDLTYLARGGRISKTSAFVGGLLNIKPLLQMEDGKLVPLEKIRGQKKLFKRIIELMKERGDDWSNQTVGISYAANKEKATDMKHLIEEAFKPKEIIMHPISSAIGSHAGPGTLAIFFLRK",
    "output": "May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPVLQWGMLCVLSLLLSIGFLAVHLPAALLLGPMIAGIIFSMRGITLQLPRSAFLAAQAILGCMIAQNLTGSILTTLAVNWPIVLAILLVTLLSSAIVGWLLVRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRMMLGDNAEAVNQHIVWFPPVSINLLLTILLAVVAGTVGCLLRLPSGTMLIPMLAGAVLQSGQLITIELPEWLLAMAYMAIGWRIGLGFDKQILLRALRPLPQILLSIFALLAICAGMAWGLTRFMHIDFMTAYLATSPGGLDTVAVIAAGSNADMALIMAMQTLRLFSILLTGPAIARFISTYAPKRSA",
    "output": "Seems to be involved in the regulation of AidB."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAASLSSRLIKGIANLKAVRSSRLTSASVYQNGMMRFSSTVPSDSDTHDDFKPTQKVPPDSTDSLKDIVENDVKDNPVMIYMKGVPESPQCGFSSLAVRVLQQYNVPISSRNILEDQELKNAVKSFSHWPTFPQIFIKGEFIGGSDIILNMHKEGELEQKLKDVSGNQD",
    "output": "May only reduce GSH-thiol disulfides, but not protein disulfides. Participates probably to the maturation of iron-sulfur proteins and to the regulation of the redox state of the BOLA proteins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAAAMVAAVHGVGRQDRSSPGGGGAPQVDTGKYVRYTPEQVEALERVYGECPKPSSLRRQQLIRECPILSNIEPKQIKVWFQNRRCREKQRKEASRLQTVNRKLTAMNKLLMEENDRLQKQVSRLVYENGYMRQQLHNPSVATTDTSCESVVTSGQHHQQQNPAATRPQRDANNPAGLLAIAEETLAEFLSKATGTAVDWVQMVGMKPGPDSIGIIAVSHNCSGVAARACGLVSLEPTKVAEILKDRPSWYRDCRCVDVLHVIPTGNGGTIELIYMQTYAPTTLAAPRDFWILRYTSGLEDGSLVICERSLTQSTGGPSGPNTPNFVRAEVLPSGYLIRPCEGGGSMIHIVDHVDLDAWSVPEVLRPLYESPKILAQKMTIAALRHIRQIAHESSGEMPYGGGRQPAVLRTFSQRLSRGFNDAVNGFPDDGWSLMSSDGAEDVTIAFNSSPNKLVGSHVNSSQLFSAIGGGILCAKASMLLQNVPPALLVRFLREHRSEWADPGVDAYSAAALRASPYAVPGLRAGGFMGSQVILPLAHTLEHEEFLEVIRLEGHSLCHDEVVLSRDMYLLQLCSGVDENAAGACAQLVFAPIDESFADDAPLLPSGFRVIPLDGKTDAPSATRTLDLASTLEVGSGGTTRASSDTSSTCNTRSVLTIAFQFSYENHLRESVAAMARQYVRTVVASVQRVAMAIAPSRLGGQIETKNPPGSPEAHTLARWIGRSYRFHTGADLLRTDSQSTDSSLKAMWQHSDSIMCCSLKAAPVFTFANQAGLDMLETTLIALQDISLEKILDDDGRKALCTEFPKIMQQGFAYLPGGVCVSSMGRPVSYEQAVAWKVLSDDDTPHCLAFMFVNWSFV",
    "output": "Probable transcription factor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR",
    "output": "This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKLLEEFIKEKGTVLPGNVLKVDAFLNHQIDPGLMQEMGKAFAERFQDLGITKIVTIESSGIAPAVFAGLALSVPVVFARKKKSVTLTDNLYTSTVYSYTKKESNDISVSKQFLTDADTILVIDDFLANGQAALGLLEIAELAGAKVAGIGIVIEKSFQQGRELLNKTGIPVYSLARIASLENEGILFLEEE",
    "output": "Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MANYSTNDFKPGLKVMLDSNPCSIMENEYVKPGKGQAFNRVKLRNLKTGKVLEKTFKSGDTLEAADIVEVEMNYLYNDGEMWHFMDPESFEQIAADKTAMGDAAKWLKDDSNETCTIMLFNGVPLNVNAPNFVVLKVVETDPGVRGDTSGGGGKPAKLETGAVVRVPLFVQQEESVRVDTRTGEYLERA",
    "output": "Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKEPPKNSREKTKNLLLKLQDNICKGLENIDGKAKFTEESWLREEGGGGKSRVLKNGSIFEQAGVNFSEVHGKELPQSIISQRPEAKGHKWFATGTSMVLHPKNPFIPTVHLNYRYFEAGPVWWFGGGADLTPYYPYLTDVRNFHKEHCNACEKVNKNLHKVFKPWCDEYFFLKHRNESRGIGGIFYDYQDGSGRIYKGNNKESKAYKESINIGELNLNWNNLFSLAENCGGAFLDSYQPIIEKRVNQNYTKEQREFQLYRRGRYVEFNLVWDRGTIFGLQTNGRTESILMSLPPLARWEYGYKAKKGSREDYLTKIFTKPQDWQNDKILEKFCKENNIFD",
    "output": "Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MADKLTHLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLARKAFFPGKLPFPVMHVDTQWKFQEMYRFRDKMVAEMGLELITHVNPDGVAQGINPFTHGSAKHTDIMKTEGLKQALDKYGFDAAFGGARRDEEKSRAKERVYSFRDSKHRWDPKNQRPELWNVYNGKVKKGESIRVFPLSNWTELDIWQYIYLEQIPIVPLYFAAEREVIEKNGTLIMIDDDRILEHLSAEEKARIQKKMVRFRTLGCYPLTGAVESTAATLPDIIQEMLLTRTSERQGRVIDHDGAGSMEEKKRQGYF",
    "output": "With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNIQIVTVGKLKEKYLVQGIAEYLKRLSAYAKVTIVEVPDEKAPEVLSDAEMKQVKDKEGARILAKIPDDAHVIALAIDGKMKSSEEFAADLDKLATYGKSKVTFVIGGSLGLSEAVLKRSNERISFGRLTLPHQLMRLVLVEQVYRAFRIVRGEPYHK",
    "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPSISININLAFATALLGMLMFRSHMMSSLLCLEGMMLSMFILSTLTILNMQFTMSFTMPILLLVFAACEAAIGLALLVMVSNNYGLDYIQNLNLLQC",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAHILGIDLGTTNSCMAVIEGGQPVVIPNAEGFRTTPSVVAFTKTGERLVGHAAKRQAITNPERTIISIKRDMGTNRRIKIDDKEYSPEEISAMILMKLKADAEAYLGEKITQAVITVPAYFTDSQRQATKNAGRIAGLEVLRIINEPTAAALAYGLDKEGHQKIMVYDLGGGTFDVSILEIGEGVIEVLATSGNNRLGGDDFDQRIIDYIADEFMKEHGIDLRKDKVALQRLKDAAERAKIELSSALQTTINLPFITADANGPKHIDMVLTRAKFEELIKDLVEKTREPVETALSDAKLTPEQIDKVILVGGSTRIPYVQEFVKKLTGKEPFKGINPDECVAIGAAIQAGVLGGQVKDILLLDVTPLSLGIETLGGVFTKIIERNTTIPTRKSQIFTTAADGQTQVEIHVLQGERPLAKDNKTLGRFILDGIPPAPRGVPQIEVTFDIDANGIVHVSAKDLGTGREQKITITSQTHLSEEEIQRAIKEAEMYAEQDRKRKELIETRNKADSIIYQTEKLLRDLGDKMTATEKEQIEAKLKALKDVMNGEDKERIERAIDELTKSFYDVSTRLYQQGYTQAGPQGGTNPGGQGGTDGNVNTDYKVY",
    "output": "Acts as a chaperone."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLGIGAFKQRIPRPGEALPGREQALPLHNTHLINGHPLRGEFTGLAQVQFGLGCFWGAERKFWKVPGVYTTAAGYAGGQTPNATYSEVCSGQTGHTEAVLVVFDEQAVSFEHLLRTFWESHDPTQGMQQGNDVGTQYRSAIYCTTQAQYAAALASRDAYQQQLTAAGYGAITTEIGFPAPTFYYAEDDHQQYLAKHPNGYCGLGGTGVSCPIGLDA",
    "output": "Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSRLARLREQLSTRDHFCDGWLLVATLSLMLIGWVMVTSASTEVATSLTGNPWYFSVRHGVFVLCSMVVALLVLRIPMAWWKANGPLLLLVGLALLALVLVAGREVNGSRRWLSVPGIPLNLQASEIAKLCLIVYLAGYLERFLPQVRRHWGAFLRPLMVMAVMGVLLIFEPDYGAVVVMTGCVMGMLLMAGAPWGRFLLLMGLVAALGAALAIAEPYRMARLTSFVDPWADQFASGYQLTQALIAFGRGEWFGTGLGNSVQKLFYLPEAHTDFVFAVLAEELGMIGAVAVIGLFALLVWRAMAVGRRAELAKRPFAAYLCYGIALVIGAQAFINIAVSTGMLPTKGLTLPLLSYGGSSLVISAVMVGMLLRVDIETRQARRREQPAAPRTGEARS",
    "output": "Peptidoglycan polymerase that is essential for cell division."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLMPYWGI",
    "output": "Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MADQLTDDQIAEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYDEFVKVMMAK",
    "output": "Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSMVYANIFLAFIMSLMGLLMYRSHLMSSLLCLEGMMLSLFVMMTVTILNNHFTLASMAPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDKIIKSISKNGHFRAFALDSTLTVKEAQERHQTWPTSTVALGRTLIAGQILGANEKGDTKITVKVLGDGAMGPIIAVADSRGHVKGYVKNRKLDYKKASTGEVLVAPFVGNGFLVVVKDMGLKQPYSGQVDLITGEIGEDLAWYFLSSEQTPSSVGVNVLLNEDSDTVKIAGGFMLQALPDATDEEITEIEHNIKSMPSIATMLTSEEPLKTMLDNIYGDMEYKNLGEFPLEFKCDCSKERFLEGIKSLGREPIEEMIAEDHGAEIICQFCENKYEYSEDELKALLK",
    "output": "Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNYTLTRILSNSKENRKSLQEDDSATLLIEQHVNSNIYLGKLKHILKSIVKWGRGNSLWPYNFGLSCCYVEMTTSFTAVHDVARFGSEVIRASPRQADFMVIAGTPFIKMAPVIKRLYDQMLEPKWVISMGSCANSGGMYDIYSVVQGVDKFLPVDVYIPGCPPRPEAYIQALLLLKEAIGKEQRPLSWIVGDQGIYRANMESERKRKHNERAKMTYLRSPEEI",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKIHVRKKDTVVVISGKDKSKIGEVLSVLPKKGKVIVKDVNVVTKHQKPNRENMQGGIIHKEAPIFSSKVMLYCDKCKSATRISNKILEDGTKVRVCKKCGETF",
    "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMSGEELGDIEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVAAVNLWFLESGKSGIFNLGTGRAESFQAVADATLAYHKKGSIEYIPFPDKLKGRYQAFTQADLTNLRNAGYDKPFKTVAEGVTEYMAWLNRDA",
    "output": "Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLLHCENSCGSSQSESDCCAAMAASSCGTAAKDDSVSGTASTVTLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEEHQAHCEFALMSCPQCQRPFQKCHLNIHILKECPRRQVPCENCAVSMAFEDKEIHEQNCPLANVICEYCNTMLIREQMPNHYDLDCPTAPVPCTFSAFGCHEKMQRNHLARHLQENTQSHMRMMAQAVQTLSLAVAPVPQCTMPLYDSVPPTRPSSGRHSEVHNFQETIQQLEGRLVRQDHQIRELTAKMETQSMYVNELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPSAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAAVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDSGI",
    "output": "E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN (By similarity). Seems to also play a role in dendritic cells (DCs) maturation and/or activation (By similarity). Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor (By similarity). Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation. Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production (By similarity). Participates also in the TCR signaling by ubiquitinating LAT (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MWIEIPECYEVLRNVFSKFRRHSLTAAMVKLLMRADTHVSFTVPAEEPVAKCTFSQVLAALSVSLGSMVVGFSSAYTSPALVSMKDRNITSFEVTDQSGSWVGGIMPLAGLVGGILGGPLIEYLGRKNTILATATPFIISWLLIACATHVAMVLVGRALSGFSVGVASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGNYMDWSELAFLGATLPVPFLILMFLIPETPRWYVSRGRDDRARKALQWLRGKKADVDPELKGIIKSHQDAERHASQSAMLDLLKKTNLKPLLISLGLMFFQQLSGINAVIFYTVQIFQDAGSTIDENLCTIIVGVVNFIATFIATLLIDRLGRKMLLYISDIAMIITLMTLGGFFYVKNNGGDVSHIGWLPLASFVIFVLGFSLGFGPIPWLMMGEILPGKIRGSAASVATAFNWSCTFVVTKTFADIIASIGTHGAFWMFGSVCVVGLVFVIMYVPETQGKSLEDIERKMCGRVRRMSSVANIKPLSFNM",
    "output": "High-capacity facilitative transporter for trehalose. Does not transport maltose, sucrose or lactose. Mediates the bidirectional transfer of trehalose. Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MARTVNCVYLNKEADGLDFQLYPGDLGKRIFDNVSKEAWGLWQKKQTMLINEKKLNMMNVDDRKFLEEQMTSFLFEGKDVEIEGFVPEKGQE",
    "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQSFAKITAQGTYVPEKVMDNNDFEKIVETSDEWIQQRTGIIERRIADENEYTSDLSYKAVLDLQEKYQVDLTDVDMIINTTLTPDYKTPSVASYVQAQLGLKNAGAIDINAACAGFTYGLNLANGLITSGQNKKILVIGSETLSKITDYNDRSTCILFGDGAGAFLVEYDKEEMSFIASNAGSDGLKGHNLYCTELSEEMFSDDLENHGYIVQNGRGVYKWAVGNVPNIIHEVLNQSNYSIEDLNWFVPHSANARMIESICEKANIETDKALKSLKYYGNTSSATIPLSIDLAIKEGKIKKDDLILLVGFGGGLAYASTLIRWTI",
    "output": "Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEELLIENSQRFTIFPIQHPECWNWYKKLESMTWTAQEVDMCKDIDDWEAMPKPQREFYKQILAFFVVADEIVIENLLTNFMREIKVKEVLYFYTMQAAQECVHSEAYSIQVKTLIPDEKEQQRIFSGIEKHPIIKKMAQWVRQWMDPARNSLGERLVGFAAVEGILFQNHFVAIQFLKEQNIMPGLVSYNEFISRDEGMHCSFACFLISNYVYNIPEEKIIHKILKEAVELVDEFINYAFDKARGRVPGFSKEMLFQYIRYFTDNLCFMMQCKSIYNVGNPFPQMTKFFLNEVEKTNFFELRPTQYQNCVKDDAFAFKLFLDDDDF",
    "output": "Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQKQRFCLDTTAITDSDVRKSLGVSNISESAEKIMDIIAQARVQLDISCHIPYNTVYKELIGFLVREECAPETLIKVNTWLVKKTPNRYEIKIPAEIFYEYIKDLRERINKGMRISENAMYETALEAYILSKPDEKDREDVLNEVLSKTVNSFRDKYRNTLRGGTLDSAPDLDVLLLAKELDAAVVANDEGIEKWAQRLGLRFVNARDFPFIIQEYLDLWDKK",
    "output": "RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "AICSLVLYLLTLMLMEKLSSNSVDAQEVELVWTILPAIVLILLALPSLQILYMMDEIDEPDLTLKAIGHQWYWTYEYTDFKDLSFDSYMIPTSELPLGHFRLLEVDHRVVVPMESPIRVIITAGDVLHSWAVPTLGVKTDAIPGRLNQTSFITTRPGIFYGQCSEICGANHSYMPIVVESTPLPHFENWSSLLSTSSSL",
    "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQDPEQFSIESILQRLKERFPTEADEISSFFDWDLVHKFTVFLKEKNEAGGFFSKRDSEEILDRHVLESIYHVYRITKKIGSWKGTQLGDAGTGPGIPGFFFRCLKEHPIVVLIDSQKRKLSHTENFVRSNQIDGVKFQFIRAEESKLSLNYVTSRGFIPYPYSIEAICNLLKINGTYVPFLGKHDMDTNLEKKVLSYSGFKLEFSEDLVPLEFLGMRHIKFLKKVSSPRHGYPRAWKEISKESKGANGKDRID",
    "output": "Specifically methylates the N7 position of a guanine in 16S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAQSIVEAPIRVDTSRKIIHVDMDAFYASIEEREHPAYKTQPLVIAHDPRQTGGRGVVTTANYVARQFGVHSAMPAAKALELCPTAVFKTPNFPLYREVSAQIHRIFHEYTEMIEPIAFDEAYLDVTTNKKHIHSAVELAHRLQQEIWHQTHLTCSTGISYNKFIAKLASDYRKPAGVTIVLPQDAEPFLLREPIEKFRGVGKKTVPKMHDLGIKTGQDLYAQSELDLIKQFGKLGYILYRRVRGSDDRPVEYLRERKSIGKERTFGPFLQSTTEVNTHLKAIAKLVAASMQSHQRHGKTLVLKLRYGDFVTITKRRTFGEFIPNDAALFEQYAEEIFEEVVDDHFNSGIRLLGITLTGLAPLAFENLTLPLYPNDN",
    "output": "Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGVVVYAPASIGNVSVGFDVLGAAVSPVDGTLLGDRVQVKAGTEPFSLNTAGHFVSKLPTDPKENIVYDCWVVFARELDKKGIELKPLEMTLEKNMPIGSGLGSSACSIVAALDALNRFHDQPLNETELLALMGEMEGKISGGIHYDNVAPCYLGGVQLMLEELGIISQEVPCFDEWYWVMAYPGIKVSTAEAREILPSQYRRQDIIAHGRHLAGFIHACHSGQPELAAKMIKDVIAEPYREKLLPGFANARQYAASAGALATGISGSGPTLFSICKQKDVAERVARWLEQNYVQNEEGFVHVCRLDKQGSKVTGSEL",
    "output": "Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MESPALSEFDLHLFAEGRHWHIYNVLGAHLVNHRGTEGTRFAVWAPNARAVSVIGDFNNWDSGRHAMAVNNGYGVWSLFIPGVKAGHLYKFAITTRNGHHITKTDPYGQAFEHRPSNAAVVTERGHYAWGDGDWLERRNRFDWQQSPISVYEVHPGSWRHHGSGRWLTYRELADQLVPYVLETGFTHIELLPVTEHPLDESWGYQTTGYYAPTSRFGSPDDLRYFVDQCHQNNIGVILDWVPGHFPDDDFALAEFDGTALYEHEDPRRGRHQDWGTLIYNYGRHEVRNFLIGSALFWLDTFHMDGLRVDAVASMLYLNYSRNEGEWLPNEHGGHENLDAIRFLQDLNRVCQSRFPGVLMMAEESTSWPRVTRPPEIGGLGFNLKWNMGWMHDTLHYLQQDPVYRQYHHDKLTFGLLYAFSENFVLPLSHDEVVHGKSSLIQKMPGDDWQQRASLRLLFSYMFSYPGAKLLFMGGEFGQRQEWSERRELDWYLLQYPEHQGLRKLVQDLNGLYRRYPALHRKSFTSEGFEWIDCHDSTQSVISFLRNPGTPEHGPLVIVANFTPIPRHHYRIGVPTGGNWQEIFNSDSTWYGGSNLGNPLLLQAEPTPWMARPCSVELTVPPLGLVMLRPAT",
    "output": "Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGHKAGFVALVGRTNVGKSTLLNAILQEKIAITSPKPQTTRNTIRGILTTDEYQVIFVDTPGIHKPKSKLSEFMIEVAKRTLKEVDLILYMIEPDTEVGPGDRYIIEHLKEVDTPVILVVNKIDLVPEKRVEETIKIFKEQYEFKDVVAISAIENKNIDLLKEKIVSLLPEGPKYYLDDYITDQPEKLIVAEIIREKMLHFLEEEVPHGVYVEVESIKEREDKDIIDIEAYIYCEKESHKGIIIGKNGQMLKKIGQSARLDLEEFYGKQVFLDLWVKTRKGWRDNTTLLKKLGYAIDKKTYE",
    "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRLLIWVLFVTLVTFVSNTTATSTFTDPQVTSGDIEALTHLLDVESNADAKRFLRTESKNDLKSDADTNGIDIEDEERGFIPSSITNAFSKMKTGWSNFKSNQFEKAFQRMNQKGETPTTLAKRLDIGKTAEKRFEKTYEKYTAWWINHHTNAGT",
    "output": "Effector protein that contributes to pathogen virulence . Targets members of the RABA GTPases subfamily to inhibit vesicular secretion, leading to an accumulation of secretory proteins in the endoplasmic reticulum ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKKVVDQFKLQIPAGKANPSPPVGPALGQRGVNIMEFCKAFNEKTKDMMGFNIPVVITVYSDRSFTFVTKQPPATDLIKKAAGIQKGSDNPLKNKVGKITQAQLEEIAKTKMPDLNTTDLEAAKRIIAGSCRSMGVEIVD",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPSNKSVSDAPITQFVNCRILKNHKLQWEDLWVREGKILNPEKLFFDEQGFADHRVDCENKIIAPGFIDVQLNGGYGIDFSQASSDIRGGVALVAKKILEHGVTSFCPTLVTSPPHIYHKVIPELRVQDGGPEGAGVLGIHLEGPFISEEKRGAHPPKFLRTFQSGGVADLMETYGQLENVAMVTLAPELTNSAAAIHELSSRGITVSVGHSMADLSQAEEAVQNGATFITHLFNAMLPFHHRDPGIVGLLTSDRIPPGRTVYYGMIADGIHTHPAALRIAHRAHPAGLVLVTDAVTAMGLPPGRHTLGQQQIDIQGLHAYVAGTTTLSGSIATMDMCVRHFREASGCTVEAALEAASLHPAQLLGISHRKGTLEFGADADFIVLDDMLTVRETYIAGQQVWRK",
    "output": "Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKKLHLISLGCTKNLVDSEVMLGRLKSYEITPLIEKADVIIVNTCGFIEAAKQESLSVLFEALERRKKGAILVASGCLSERYHEELLREIPEIDIITGVGDYDKIDQMVRERQGFHSGEVFLASEEQERVITGSSVHAYVKLSEGCNQTCSFCAIPQFKGKLHSRTLESTLKEVKNLIAKGFTDFSFIAQDTSSYLRDRGEKEGLIQLIGALDSLEGIKSARILYLYPSTASAKLIQAIQKSQVVQNYFDMPLQHIAESMLKRMKRGANQKKHKELLERMRQVPHSFVRTTLILGHPGESEEEFEELCRFLEEFRFDRVNLFAYSDEEGTSAHKMEGKLDKRVINARLKRLDKIIQKQHRALLKEMVGQEIPVILEGGSSEHEFFYSARDARWAPEIDGEILINETLLPQPAPGHYWAKITQVAGKQLLATLTRRWEK",
    "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKIALPRKFFGRRFEVLEPPYLLSIPKNSFENFVQLKVNPYKRKNVGLEHIFRTSFPFKDPDENFILEYLGYEIGDWECNRCGYKPKDDLLGGWDVDCPQCGAKLVYKEKFTPEECKLKGLTYSAPLRVMLQLKAKTKNGYREFPPKKVYFGEIPLMTETGSFIINGTERIIINQLIRSSGVFFDEKEEKQKDATITRILYRGSIIPDKGSRVEFELSGATDLISARIDRKKLSATAVLRAFGLETAYDILKYFYEDVRKFIVKDKYLYDAQTGEEFTPEDLEHHYIFAIIKFRGKLVGFASSKERDFIEERYIEEWEDLVRLLDDDRIEVLSVTAVPRDVVIKSPYGKSLIDTLANDTSPKDVDKRSPVKVPAEYTLRDYGLMEMYKRLRHIEAITMEIDSVIERARIFFNVFFRDLKRYDLSRVGRVKINAKVHRIPKVLKPADVDLLDQLPPLALAEDYGEYKAGTRVTKDLLKELFKQYKEIKVKDYTEDEARFILPIDLVNILKYLIDLRHGRVKKDDIAHLGNRRVRSVGELLENQARLGIAKMEKVFRDRSAVINPEQPDLKPQDFINPRYVTTAITDFLKTGQLSQYLDNTNPLSELTHKRRLSALGPGGLTRESAKFEIRDVHPSHYGRICPIETPEGQNIGLVTSPTVYARVNEYGFLITPYRKVENGKVTDKIEWLAAYEEENYVIAQSTPTDEEGRLKAEFILARHKNDIRLVKPEQVEYIDVSPRQVISPSSSLIPFLEHDDANRALMGSNMQRQAVPLIFTQAPLIGTGMEKKIARDSHAVVVAKRGGVVEEVDSSKIIIRVNPEEINFDDPLDIGIDIYELRKFQRTNQKTCVNQRPIVRKGEKVEKGQIIADGHSTDRGELALGKDVLVAFMPWRGYNFEDAIVISERLVKEDVYTSIHIEELEVEARETKVGEEEITRQIPGVPERALAHLDEHGIVRVGTYVKPGDILVGKVTPKGETRLTPEEKLLQAIFGEKTRDVKDASLRCPPGVEGIVIDVQVFTRKGTGKKDMLAEKVEREELEALEQELEKKKNLIITGRDKVLKGLVLGRKVEKDAKVGRKTVKKGTVIDEKVFEEFVNYILGRPENFFEDEDLIRKIREIAERTRTQIEMLNKVYEEKKETLLKRRDLPPGVITLVKVFIANKRKIKVGDKMAGRHGNKGVISVVLPVEDMPFLPDGTPVDIVLNPLGVPSRMNVGQILETHLGWAAKELGKKIGEMIEKGRDRKAITEYLKEIFAIGDKDGENAKFIEEFLNSLSEEEFWSVVRDYAERGIPMATPAFEGAEEDAIKELLKKAGLPENGKTTLYDGRTGEPFDFEVTVGYMHMLKLIHMVDDKIHARATGPYSLVTQQPLGGRAQFGGQRLGEMEVWALEAHGAAYTLQEMLTVKSDDVEGRTKVYEAIVKGKYTYTPGIPESFKVLVRELKALGLNVKCLNGEEKPCDEVEVKEEEEK",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MYAIIRTGGKQYKVQAGDVVQVDKLEQALGAEFEINEVLMVGGESTAVGQPLVKGAKVTVVVTKQAKTRKEIVFKKKRRQGYRKFATHKQEFTELFVKAISFDGKTAKSDEAATVVDVKAVRAEKAQARVAARKERAANKGPAEVVKKAAKKVAKKKVAKKAVKKTVKKATKTGAKKKAAKKTSKKA",
    "output": "This protein binds to 23S rRNA in the presence of protein L20."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARSKIALIGGGQIGGVLAQLAALRELGDVVLFDIVEGLPQGKTLDIAEAAPVDGFDVSLKGTNTYEDIKGADVVIVTAGLPRKPGMSRDDLIAVNSKIMTTVAEGIKQYAPNAFVIVISNPLDAMVTLCQRITGFPHNRVVGQAGVLDSARFAAFIAWELGVSVKDVTAVTLGGHGDDMVPLVRYTSVCGVPVMELLEQKYGAAKAAEVMAAMVKRTRGAGGEVVALLKTGSAFYSPASSAIAMAESFLKDQKRVLPTCAFLKGEFGVDGLYVGVPVVIGAGGAERVLQLKLNAEEQAMMDKSVKAVKDLVATLK",
    "output": "Catalyzes the reversible oxidation of malate to oxaloacetate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MHASTGKGSKIKYSRVLFKISGEALMGSRPFGHDMELIDQLCKDISDIYKLGVQVCIVVGGGNIFRGASASLSGCERASSDYIGMLATIINALILQNFLEKNSVNSKVLSAIPMVTICEPYIRRKAIHHLEKGRVVIFAAGTGNPFFTTDTAAALRAVETNCDAILKGTQVNGVYSADPKKNEDAVMYDRLSYMDLLTRDLKVVDASAISLARENSIPIIVFSLKEEKIVNIVKGHGTYTIVSDCE",
    "output": "Catalyzes the reversible phosphorylation of UMP to UDP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSASTQQEPSLILITGMSGAGRRATAAALEELGWYVADNLPPELIVRMVELSFSDDSPIEKLAIVTDVRSRDFAGNLTSVLHDLHTGGRRPTVLYLDATDEALIARFDAVRRTHPLQQKGTLQDGIDREREMLTSIRERADIVLDTTNRSIHDLRRELEKFFAAADHSSVRINVQSFGFKHGPPKDIDMLLDARFLPNPYWDPELRPFKGIDAPVSDFVLSQPGAQAFLDHIVGLIHSVLPGYRKEGKFFVSVAIGCTGGHHRSVAIVEELTRRLADDGVLVNLSHRDLER",
    "output": "Displays ATPase and GTPase activities."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKKDGAIEVEGRVVEPLPNAMFRIELENGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLSRGRIVYRYK",
    "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKPLKGCPVAKDVRVAIVGSCFNSPIADRLVAGAQETFFDFGGDPSSLTIVRVPGAFEIPCAIKKLLSTSGQFHAVVACGVLIQGETSHYEHIADSVAAGVSRLSLDFCLPITFSVITAPNMEAAWERAGIKGPNLGASGMKTALEMASLFSLIGKE",
    "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSWSGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVSTGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMKRHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNNL",
    "output": "Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKLLSLHVQDFRNLAAVELAPSPRATVLLGENGQGKTNLLEAIYFLTTLKPLRAVRLAELVRFGAEQGAVAGDFEGPGGVRRVAVQVAAGGRTATLDGKALGSGARLDDYFEGLASVCFSPDDLLLVKAGPDGRRRFLDRAAFNRWPAVLGEAREYVRALRARNAALRAGPAEVEASFREPLVRAGARILVRRRDLVAELAPRLQAAFAEISGPAAPEAHLAYRAAGGVDVEHPEAEVAARLAHALEARLERDREKGFTSAGPHMDDLVLALGGKGARLYGSQGQQRALVLALKIAEIENLRAALGRPPLLLLDDVSSELDPAKNRFLLGYLAALPAQAFLTSTDRRLIEPAAGPDTAFFEVRSGVVSPLVS",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGSSPQSSTRTLLGLLFLLLVQLSSALKFDLHASSGHNERCIRNFVFKDQLVVVTAIVSGQRGDGQVVNMHIKDALGNDHGRPKDIAGETRQAFTSVADTAFDVCFENKLVSHHGVANPYKSVELDVEIGADARDWSSVQAAEKLKPVETDLRRIEEMVAEIVNEMEYLRAREQKLRDTNESTNERVKWFAFGTMGMLVGLGVWQVVYLRAYFRYVDFPVSWRVDGVVANCCSCCEQVEASYLRSSRVVFWSPLVMWTRLSWLILR",
    "output": "Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "EEDRKCPKILMRCKRDSDCLAKCTCQESGYCG",
    "output": "Inhibits trypsin."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTINPVSRKVAWLRVVTLAIAAFIFNTTEFVPVGLLSDIAESFHMQTAQVGIMLTIYAWVVAVMSLPFMLLTSQMERRKLLICLFVLFIASHVLSFLAWNFTVLVISRIGIAFAHAIFWSITASLAIRLAPAGKRAQALSLIATGTALAMVLGLPIGRVVGQYFGWRTTFFAIGMGALITLLCLIKLLPKLPSEHSGSLKSLPLLFRRPALMSLYVLTVVVVTAHYTAYSYIEPFVQNVAGLSANFATVLLLILGGAGIIGSLVFGKLGNRHASSLVSIAIALLVVCLLLLLPAADSEAHLAILSIFWGIAIMVIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSAIGYIGDIPACAALVWAVLIFRKWPVTLEEQPH",
    "output": "Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDDNGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLTLMREMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPAPARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPAGVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQRVEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREELTRRRIAAVASWKEQRCPKPD",
    "output": "Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSNIPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQTSFDVIVIGGGHAGCEAAAAAARLGATTALVTHRFATVGAMSCNPAIGGLGKGHLVREVDALDGLMGRVADQGGIQFRMLNRRKGPAVRGPRAQADRKLYAAAMQALILATPHLSVVEAEADDLLTSDGRITGIRLADGRELGAGAVVITTGTFLRGLIHLGERSWPAGRIDEAPALGLSKSFERLGFALGRLKTGTPPRLDGRSIDWGAVEMQPGDEPPEPFSVLTEKITNPQIECGITRTTPATHAVIRANVHRSPMYSGQIQSSGPRYCPSIEDKIVRFGDRDGHQIFLEPEGLDDPTVYPNGISTSLPEEVQRAILATIPGLQRTTMLRPGYAIEYDHVDPRELEPTLQAKRLRGLFLAGQINGTTGYEEAAAQGLVAGLNAALLASGGGEIAFDRADGYLGVMIDDLVTRGITEPYRMFTSRAEYRLTLRADNADQRLTGQGIALGCVGAERTEFHTAKMAALAQAKALAQSLAITPSQAAKHGLSLNRDGVRRSAFELLAYPEVDWARVEAIWPELAAIEPSIATHLEIDATYDVYLKRQTADVEGFRRDEGLLLTEIDYALVPGLSNEARGRLEKARPRTVGQAGRLDGLTPAALGILAAYLRRDQRRKPAGSAAG",
    "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAINIIAQLEQEESARLLAARAIPDFRPGDTLRVNVKIKEGERERVQAYEGVCIARAGTGVHESFTVRKISFGEGVERLFPLLSPSIESIEVKRRGVVRRAKLYYLRDRRGKSARIAERAGGPKASASTEA",
    "output": "This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKFDLTTAYTLSIPLLASSGTVLATTADTSSKSSTMTAIHTSTGYNNHSDSLWATFNNNVALTWDAPNNEFYLPVITWHNRYTYDKEKTDKYNERPWGFGYGKYRYDKDNDWHSLYAMAFMDSHNRLEPIIGYGFQKMWIPGDLDGFRLGVGFTLSVTARHDYYYVPIPLPLPLFSVEYDQLSFQGTYIPGTYNNGNVFFAWLRWQW",
    "output": "Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MALPRLRVNASNEERLVHPNHMVYRKMEMLVNQMLDAEAGVPIKTVKSFLSKVPSVFTGQDLIGWIMKNLEMTDLSDALHLAHLIASHGYLFQIDDHVLTVKNDGTFYRFQTPYFWPSNCWDPENTDYAVYLCKRTMQNKAHLELEDFEAENLAKLQKMFSRKWEFVFMQAEAQYKVDKKRDRQERQILDSQERAFWDVHRPVPGCVNTTEVDFRKLSRSGRPKYSSGGHAALAASTSGIGCTQYSQSVAAAHASLPSTSNGSATSPRKNDQEPSTSSGGESPSTSSAAAGTATTSAPSTSTPPVTTITATINAGSFRNNYYTRPGLRRCTQVQDTLKLEIVQLNSRLSKNVLRTSKVVENYLAYYEQRRVFDPLLTPPGSQADPFQSQPNPWINDTVDFWQHDKITGDIQTRRLKLWEDSFEELLADSLGRETLQKFLDKEYSGENLRFWWEVQKLRKCSSRMVPVMVTEIYNEFIDTNAATSPVNVDCKVMEVTEDNLKNPNRWSFDEAADHIYCLMKNDSYQRFLRSEIYKDLVLQSRKKVSLNCSFSIFAS",
    "output": "Involved in egg-laying and locomotion. May regulate G protein goa-1 signaling. Plays a role in regulating dopamine-mediated locomotion behavior ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MALSPKRVKYRKVQRGRVKGDATRCNAVDFGAYALVCLEPFWLTSRQIEAARVALNRRIKRGGKLWIRVFPDKPYSKKPAETRMGKGKGSPEYWVAVVKPGTVLFELMGVERALAEQAMLLAGSKLPIKTRFAERVQEI",
    "output": "Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVWRRRWWRRRRRPVWRRRYRRWRRRRRWRRRPRRRRRPYRRRPYRRYGRRRKVRRRRRRTLVVRQFQPPYQRRCRVSGLEPLLYFGKKEEERHFYGNRQIMKDVDQTEGGGVTDGVFSLEELYESYQEGWNHWSASNQMLPLVRYFGCKITLYRSATDSYIFWWTNRPPFQVDRQFWVGMHPYWMLRRGRKVVMLSKQLKPFAKDHVTIKIGPPALMKTKWYFARDFCKTWLLQWRACFFNPIDPYIPRGANNTTVTFYGFPGHSYPSQSLYYTWQEHLAETNVWGITNESEKTKFEALRKAWNEQATKGPVAGYKAVLQAMNAWASVAAPGPEGSNFAKGTNVALGLANLLWLIYSQYYWQNRSPSPWGLPGATLEAMKHPEAWKPYAYKYSWSHDKGKGNRFAICDWPYKDQHGEQTTPLNFDLEIKDAPLWWCVTAAYDWAIRQGKNPANWSFFVRSDYTWPRADNIILAYSSYFADNVVKNKYADPQHATGGYFTLYRAPNLIDGREAIDIIYRNGPFAPKQEESTGNATIKYRFYFKWGGTQRPPRPQPTDPCQQPRWEGPNFPPFDGRARIDNPSDQDPRSYFWPFDTRRGSLTASAVDRVKRSLDAVTEPSETRLREGEETYGLPPPEKRARWGFPSILPTENPTDEDERYLEAEADTSSSDATDGVPETPFELLQHIQRDRDKRRELRGRLARLILRLRRRQDPELQNYYP",
    "output": "Self-assembles to form an icosahedral capsid with a T=1 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins. The capsid encapsulates the genomic DNA. Capsid protein is involved in attachment and entry into the host cell (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MALHTVLIMLSLLPMLEAQNPEHANITIGEPITNETLGWLSDKWFFMGAAFRKLEYRQAIQMMQTEFFYLTTNLINDTIELRESQTIGDQCVYNSTHLGFQRENGTFSKYEGGVETFAHLIVLRKHGAFMLAFDLNDEKKRGLSLYAKRPDMTLELREVFQKAVKHVGMDESEIIFVDWKKDKCGQQEKKQLELGKETKKDPEEGQA",
    "output": "Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain (By similarity). Appears to function in modulating the activity of the immune system during the acute-phase reaction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSASDLHPVQAGAPQGRRQILVTSALPYANGQIHIGHLVEYIQTDIWARTMRMHGHEIYYIGADDTHGTPVMLRAEQEGVSPKQLIERVWREHKRDFDSFGVSFDNFYTTDSDENRVLSEKIYLALKEAGFIAEREIEQAYDPVKQMFLPDRFIKGECPKCHAKDQYGDSCEVCGTTYQPTDLVNPYSVVSGATPVRKTSTHHFFRLSDPRCEAFLREWVSGLAQPEATNKMREWLGDAGEAKLADWDISRDAPYFGFEIPGAPGKYFYVWLDAPVGYYASFKNLCERRGLDFDAWISKDSTTEQYHFIGKDILYFHTLFWPAMLEFSGHRTPTNVFAHGFLTVDGAKMSKSRGTFITAQSYIDAGLNPEWLRYYFAAKLNATMEDIDLNLEDFQARVNSDLVGKYVNIASRAAGFLIKRFDGRVQASATNHPLLVTLRDAIPQIAAHYEAREYGRALRQTMELADAVNGYVDTAKPWELAKDPANAVALHETCTVSLEAFRLLSLALKPVLPRVAEGVEAFLGIAPLTWADANKPLSSEQPIRAYQHLMTRVDPKQIDALLAANRSSLQGAAAADAAGATNGNGAKAAKSAKAANAASADDEASPFISIDDFAKIDLRIAKIVACQAVEGSDKLLQLTLDVGEEKTRNVFSGIKSAYQPEQLVGKLTVMVANLAPRKMKFGLSEGMVLAASAADEKAEPGLYILEPHSGAKPGMRVK",
    "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTNIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNVGVILLFTTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGISSDTDKIPFHPYYTIKDILGALLLILVLMLLVLFTPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILVLVPALHTSKQRSMMFRPISQCIFWILVADLLTLTWIGGQPVEHPYIIIGQLASITYFLLILVLMPVASTIENNLLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKLLALAVLLLAVCSLEGAFVRRQAEEPNLQSLVAQYFQTMTDYGKDLLEKAKGPELQAQAKAYFEKTQEQLTPLVKKAGTDLINFLSNFMDLRTQPATQ",
    "output": "May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSPSPPAPVACAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLKDATSNEQQELFCQKLQQCCVLFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNQTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELQLKKALEKQNNAYNMHSIRSSTSAK",
    "output": "The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPKVRTKDLIEQFQLELISGEEGIHRPIDTSDLSRPGIEMAGFFTYYPADRVQLLGKTELTFFDTLTSDQKQERMKALCTEETPCIIVTRNQDVPDELLQASRESGMPLLRSSQTTTRLSSRLTNYLEGKLAPTTAVHGVLVDIYGVGVLITGQSGVGKSETALELVKRGHRLVADDSVEIRQEDEDMLVGSSPDLIEHLLEIRGLGIINVMTLFGAGAVRNYKRITLVINLEIWDQKKNYDRLGLDEEKMKIIDTELTKITLPVRPGRNLAVIIEVAAMNFRLKRMGVNAAQQFSERLMSAIELGNQE",
    "output": "Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLNINNKIAKGGYVYSKNIRLAKSKIDKQKCYDVREACSIIKEISFAKFNETVDIAIKLGVNPSHSSQVVRGVAAMPSGTGKTVKVAVICQEEKLDEFKTTGADIVGSLDIIEAIKSGNIDYDVYITTPAMMVAVSQVARILGPKGLMPNPKLGTVTNDVAAVVKKVKSGQVEFKVDKAGNIHAGIGKISFSIDEIEANINALVSAIIKSKPSEAKGTYLNGIYLSTTMGPSVRLEISNFTESGNERR",
    "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVMTDPIADFLTRIRNANMVKHDKLELPASKIKKEIAEILKREGFIRDVEYIEDDNAGTIRVFLKYGATGERVITGLKRISKPGLRVYAKSTEVPKVLNGLGIAIVSTSQGVLTDKEARAKQVGGEVLAYVW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFLIITRDTMFFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVIIDTLMNNVFHSNFLTQIERLKPVHVIIFSPFNIKRCLGKVPVTFVPRTITIIDFVALINGSYCSVPEANVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNLKRINELVRHQHIDYLV",
    "output": "May act as a transcriptional regulator of dctA (By similarity). Could be involved in the regulation of the genes coding for the type III secretion system in enterohaemorragic strains."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKVKRYINITKPGIIMGNLISVAGGFLLASRGEVDGLLMLMTVLGLSLVVASGCVLNNCIDTDIDAKMQRTRNRATVTGDVSIARALQFGLALAVLGFGLLIRYTNSIAVGFAVLGYAVYVGVYSLYMKRKSVYGTLVGSLSGAVPPVVGYCAASGQFDAGAAILLLMFSLWQMPHSYAIAIFRFDDYAKANIPVLPVAKGIAKTKLHIVLYIAVFAIVSALLPLSGYTGLTFMAVACVTSLWWLFMALRGYRKNIELVVWARQVFGFSILTITALSIGMAFDFQALPPSLLVMLS",
    "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF",
    "output": "Intercellular signal essential for a variety of patterning events during development."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKKIKVGIVGATGYTGVELLRLLAAHPDVEVAAVTSRSEAGTAVADYFPSLRGVYGLAFQTPDEAGLEQCDIVFFATPNGIAMKDAPRLIEQGVRVIDLSADFRIRDIPTWEHWYGMTHAAPDLVSQAVYGLSELNREAVAQARLVANPGCYPTCVSLPLVPLLRQCRLKPGMPLIADCKSGVSGAGRKGNVGSLLCEAGDNFKAYGIAGHRHLPEIRQTIAGLQDGIAEGFVFTPHLAPMIRGMHATVYLHLSDGSDPETVLRDYYRDSPFVDILPTGSAPETRSVRGANLCRISIQQAAQSDVWVVLSVIDNLVKGAAGQAVQNMNIMFGLEETHGLDAIPLLP",
    "output": "Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSYKKLYQLTAIFSLPLTILLVSLSSLRIVGEGNSYVDVFLSFIIFLGFIELIHGIRKILVWSGWKNGS",
    "output": "Protects a microcin H47-producer cell against microcin H47."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPKVIFLPNEDFCPEGMVVDAATGDNLLEVAHNAGVEIHHACDGSCACTTCHVIVREGFDSLNETSDQEEDMLDKAWGLEMDSRLSCQCVVGNEDLVVEIPKYNLNHANEAAH",
    "output": "Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLDIQFIREHTDIVKESQRKRGESVELVDEVLSSDTARREALKAFEEARAQQKEIGKKVASVPADEKAKLIAETKELSQTVAEYKAKADSAAEEYTTAMWRLSNIVEPEAPEGGEDDYVVVKKVGQIRDFAAEGFEPKDHLTLGAGVAGIDMRRGVKVGGSRFYFLRGQVARMQIAMLTMAVDQAEEHGFTLAITPTLVRPEVMRGTGFLNSHADEIYRLREPDDQYLVGTSEVALAGMHENEILDLGNGPLRYCGWSSCYRREAGAAGKDTSGIIRVHQFDKVEMFVYAKQEDSYKEHEHLLAMEQEMLAKVEVPYRIIDTAAGDLGSSAARKFDCEAWVPTQGRYRELTSTSNCTEYQARRLNIRERMEDGGTRPVSTLNGTLATTRWLVAIMENHQQKDGSIEIPKAMRAYMGGKEVIEPTKWEA",
    "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKTWKDVIGNEKTQPYFQHILAQVHQARASGKVVYPPQADIFNAFKLTEFDQVKVVLLGQDPYHGPNQAHGLAFSVKPPVAPPPSLMNMYKELSNEYPDFHMPNHGSLEQWAQQGVLLLNTVLTVERGQAHSHADFGWETFTDHVIHALNEQREHLVFLLWGSHAQKKGQFIDRSKHCVLTAPHPSPLSAHRGFFGCGHFTQTNDYLRRHHISEINWQLDNI",
    "output": "Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGINFDVSRPKARSSINMITKFHTIGLIGKPHHQGTNQTLKRLHHWLTMQGFEVLVEERVAAELGPNIEAVDLLEIGARCDLAIVVGGDGNMLGAARVLARFDLGVIGVNRGNLGFLTDLPPDAFEEALAKVLDGEFDTEHRFLLEAEVYRHGMLKASNTAVNEAVLHPGKIAHMIEFEVYIDDQFMYSQRADGMIVSTPTGSTAYALSAGGAILTPNLQALILVPMFPHTLSCRPIVVDACSTIKMVVSPDNGENLEVSCDGHVHLAVLPGDEIIVRRSSERLRLIHPKGHNYFHVLRTKLGWGSKLF",
    "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "METLFNGTLALTGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKASYFGGIYDTWAPGGGDVRKITNLTLSPSIIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRALVWSGEAYLSYSLAALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN",
    "output": "One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEFLERTYLVNDKAAKMYAFTLESVELQQKPVNKDQCPRERPEELESGGMYHCHSGSKPTEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTSFLLSLFSLWLSSKPPSKRLTFGWHRAEILGALLSILCIWVVTGVLVYLACERLLYPDYQIQATVMIIVSSCAVAANIVLTVVLHQRCLGHNHKEVQANASVRAAFVHALGDLFQSISVLISALIIYFKPEYKIADPICTFIFSILVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCEDPCD",
    "output": "Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRHVPRKRFGQNFLRDPGVIQEIVAAVGPAPSDRLVEIGPGEGVLTRELLQSGACLEAIELDRDLVAALKRRFAGVGRLRIHEGDAMKFDLRTIATGERLRVVGNLPYNISTPLLFHLFDQIDVIEDMHFMLQKEVVDRLCAGAGDDHYGRLSVMAALYCQAQHLFDVGPECFHPQPKVVSAVVRLVPHAVPPDAGMVKQVSAVVVAAFGQRRKTLRNALKGLLDETAMVRAGIDPGARAEELSLADYVGLSRQLNP",
    "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTSSSSDRSPLASQLGEVPAPLYARVKQMIVSQIQSGAWPPHHRVPSESELVSQLGFSRMTINRALRELTSDGLLVRMQGVGTFVAEPKGQSALFEVHNIADEIAARGHRHRCQVITLGEEVAGPERALALDVREGQRVFHSLIVHYENDIPVQIEDRYVNAAVAPDYLKQDFTRQTPYAYLTQVAPLTEGEHVVEAILAEPAECKLLQIERGEPCLLIRRRTWSGRVAVTAARLLHPGSRHRLEGRFSS",
    "output": "Repressor which binds to the hutP region in the histidine utilization (hut) operon. It blocks the expression of all the hut genes in the absence of inducer (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTTHLVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWATHNMSPRQAELINAQLNGLQIALAEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFYNYQYEVNERARDVEVERALRNVVCEGFDDSVILPPGAVMTGNHEMYKVFTPFKNAWLKRLREGMPECVAAPKVRSSGSIEPSPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQNGAGEYEQQRDFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWLNELIWREFYRHLITYHPSLCKHRPFIAWTDRVQWQSNPAHLQAWQEGKTGYPIVDAAMRQLNSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTDAAPYFRIFNPTTQGEKFDHEGEFIRQWLPELRDVPGKVVHEPWKWAQKAGVTLDYPQPIVEHKEARVQTLAAYEAARKGK",
    "output": "Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPLSYQHFRKLLLLDDEAGPLEEELPRLADEGLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSTVPVFNPEWQTPSFPNIHLQEDIINRCQQYVGPLTVNEKRRLKLIMPARFYPNLTKYLPLDKGIKPYYPEHAVNHYFKTRHYLHTLWKAGILYKRETTRSASFCGSPYSWEQELQHGRLVFQTSTRHGDESFCSQSSGILSRSPVGPCIRSQLKQSRLGLQPQQGSLARGKSGRSGSIWARVHSTTRRSFGVEPSGSGHIDNSASSASSCLYQSAVRKTAYSHLSTSKRQSSSGHAVELHNIPPSCARSQSEGPISSCWWLQFRNSEPCSDYCLTHIVNLLEDWGPCTEHGEHNIRIPRTPARVTGGVFLVDKNPHNTTESRLVVDFSQFSRGSTHVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHIPLHPAAMPHLLVGSSGLPRYVARLSSTSRNINYQHGTMQDLHDSCSRNLYVSLLLLYKTFGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLFTSITNFLLSLGIHLNPHKTKRWGYSLNFMGYVIGSWGTLPQEHIVLKIKQCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQSKQAFTFSPTYKAFLCKQYLHLYPVARQRSGLCQVFADATPTGWGLAIGQSGMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLLHLPFRPTTGRASLYAVSPSVPSHLPVRVHFASPLHVAWRPP",
    "output": "Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids. This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode. Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid. Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein. Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome. After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA). The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF",
    "output": "Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MMNHTPLLLGIRERLIFALDVPSRTQALEWIDQLGDAISFYKIGMELLASGEYFQVLDDLASRGKRVFVDLKFFDIPATVAGVIRRLSQWPISYCTIHGWHAPMMQAATEANTSNMHLLAVTVLTSMTREDLAKMGINREPVDVVVERALAAHMAGMSGVIASGQEAAAIRHAIGSGFSIVCPGIRTNHVPHNDQQRTIGIKAAFANGADAIVVGRPIRMAQDPQAAAEAMQTEIMTALTEPST",
    "output": "Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPNIKSAIKRVRTTENAEARNISQKNAMRTAVKNAKTAINNNADNKAELVNFAIKSVDKASQSNLIHSNKADRIKSQLMSSSK",
    "output": "Binds directly to 16S ribosomal RNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MESLNALLQGMGLMHLGAGQAIMLLVSLLLLWLAIAKKFEPLLLLPIGFGGLLSNIPEAGLALTALESLLAHHDAGQLAVIAAKLHCAPDVHAIKEALALALPSVQNQMENLAVDMGYTPGVLALFYKVAIGSGVAPLVIFMGVGAMTDFGPLLANPRTLLLGAAAQFGIFATVLGALTLNYFGLISFTLPQAAAIGIIGGADGPTAIYLSGKLAPELLGAIAVAAYSYMALVPLIQPPIMKALTSETERKIRMVQLRTVSKREKILFPVVLLMLVALLLPDAAPLLGMFCFGNLMRESGVVERLSDTVQNGLINIVTIFLGLSVGAKLVADKFLQPQTLGILLLGVIAFGIGTAAGVLMAKLLNLCSKNKINPLIGSAGVSAVPMAARVSNKVGLESDAQNFLLMHAMGPNVAGVIGSAIAAGVMLKYVLAM",
    "output": "Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPRYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITGPYSYEQVLQHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGDVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTSMVSLCEQLSKLGVWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGAGANELPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIVDEVDEEGAIGRSMADAPEIDGAVYLNGETNVKPGDIVRVKVENADEYDLWGSRV",
    "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDGGTFDIQPIGRFYGSNTTIRRPREITCFSYDAEHKFHLGDSSLRYYYTPRLPADLNRGFDTFQKLDDTADEHLDALLETIMALEKETGKRCEADIITWRGMMTKILTAPFDNLNGFEMNATCFQVGGENNLYKIQQKQIQENQRMPPGMASQDLMAYWGYKFETLCLLQQPWDPTPRAEIESREDLVVNNNAQYCSVVRTGIGSTRLIIGGEVDAVWDCKPDRKEDPINWVELKTSAEIRNDRDMIKYERKLLKFWAQSFLLGVPKIIVGFRDNHGIVHRLEELETASIPNKVKKLGRGTWDGNICINFAAAFLEWLKSTIKEGGTWRIRKLEKSSLIQVFKIEETGTGDIISRSFLDWRSRS",
    "output": "Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity). The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity). Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (By similarity). Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNINKSNLIWLDLEMTGLEPETDKILEIATVVTDADLNILAEGPTIAIHQSNELLDNMDEWCTTQHGKSGLTARCKASTYDEAYAVEQTIAFLKQWVPAGASPMCGNSIGQDRRFMNKYMRELEDFFHYRNLDVSTIKELARRWKPEVLAQVNKKGSHLALDDIKDSIMELKVYREKFFNL",
    "output": "3'-to-5' exoribonuclease specific for small oligoribonucleotides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAAKDVRFSSDARDRMLRGVEILANAVKVTLGPKGRNVVIEKSFGAPRITKDGVSVAKEIELADKFENLGAQLVREVASKQNDAAGDGTTTATILAASIVKEGTKAVAAGLNPMDLKRGIDHAVEAIVADLKANSKKVTSNDEIAQVGTISANGDKSVGDMISTAMQKVGNEGVITVEEAKSLETELDVVEGMQFDRGYLSPYFITNAEKMIAELEDPYILVHEKKLSSLQAMLPVLEAVVQTGKPLVIIAEDVEGEALATLVVNKLRGGLKVAAVKAPGFGDRRKAMLEDIAILTGGTLISEELGIKLENVTLAMLGRAKRIRIDKEATTIIDGAGNKDDIEGRISQIKAQIAETTSDYDREKMQERLAKLAGGVAVLRVGGSTEVEVKEKKDRVDDALNATRAAVEEGVSPGGGVALLRAIKALENLPTDNSDQKAGIEIVRKAIQTPAKQIVDNSGGDGAVVVGKLLESNEYAFGYNAQTGEYGDMVKLGIIDPTKVVRTALQDAASIAGLLITTEATITEAPKKEAPLPPMGGGGMGGMGGMDF",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSELLSVALFLASVLIYAWKAGRNTWWFAATLTVLGLFVILNITLYASDYFTGDGINDAVLYTLTNSLTGAGVGKYILPGIGIALALVAVFGALGWVLRRRRHHPHHVGYSLLALLLALGSVDASPAFRQITELVKSQMRDGDPDFAVYYKEPAKTIPNPKLNLVYIYGESLERTYFDNDAFPNLTPELGALKNEGLDFSHTMQLPGTDYTIAGMVASQCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKSHGFDHLYGAEELKTVVADPSYRNDWGFYDDTVLDEAWKKFEALSRSGQRFSLFTLTVDTHHPDGFISRTCNRKRYDYDGKPNQSFSAVSCSQENIAEFINKIKASPWFKDTVIVVSSDHLAMNNTAWKYLNKQDRNNLFFILRGDKPQQETLAVKRNTMDNGATVLDILGGDNFIGLGRSSLSGQSLSEVFLNVKEKVLAMKPDIIRLWNFPKEIKDFTVDRDKNMIAFSGSHFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWIDRCYKMAQLWAPALALSTDWCVSQGQLGGQQTVQHVDKAQWQGKTAFKDTMIDMERYKGNVDTLKIVDNDIRYKADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKAPLPKKFDLVITAKAFGDNANRPIPVRVGNEEQTLVLGHDVSTITLHFNNPTDANTLVIAPPAPVSTNEGNILGHSPRKLGIGMVEIKVVNVES",
    "output": "Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARLKDYYQKELVAKLKTELGLDNIMEVPAIKKITLNMGVGDAAKDKKIMTFALNDLTAIAGQKPVVTKSKKSIAGFKIRDGWPIGAKVTLRGDRMYEFLDRLITIAIPRIRDFRGLSAKSFDGRGNYSLGMREQISFPEIDYDKVDSIRGLDISITTTAKNDDQGRALLKAFGFPFKS",
    "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRIIGLTGGIATGKSTVARILERHGIPVADADQMARQALAVGSPIRERVLQRYGRAIQDPSGALDRRQLGRIVFADAAERAWLEAQIHPFVKARLREFLEAHGASAPPEEATEARPSCQCPHGEGHPTVCLMIPLLFEAHMENWASEIWVVTCTPEQQRQRLAQRDLLTAAEIEARLASQWPLEEKARRAHVVLDNSGSLAQLEAQVRQALGAHPREGGAICPTPPSRIE",
    "output": "Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEGIQHPIPRTVEEVFSDFRGRRAGLIKALSTDVQKFYHQCDPEKENLCLYGLPNETWEVNLPVEEVPPELPEPALGINFARDGMQEKDWISLVAVHSDSWLISVAFYFGARFGFGKNERKRLFQMINDLPTIFEVVTGNAKQSKDQSANHNSSRSKSSGGKPRHSESHTKASKMSPPPRKEDESGDEDEDDEQGAVCGACGDNYGGDEFWICCDACEKWFHGKCVKITPAKAEHIKHYKCPSCTTSKKMKA",
    "output": "Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSNNAAYAVTPVKTTSTSSRTTFHFAAGLCSGLTSSILLQPADLLKTRVQQSQKTASLLPTIKTILSSPHPIRGLWRGTLPSALRTGFGSALYFTSLNALRQGLAQTEASMAIAASSSDGKSRTSSSALPKLSNWGNLATGAVARTAAGFVMMPVTVLKVRYESDYYAYRSLYSAGRDIVRTEGVRGLFSGFGATAARDAPYAGLYVLFYEQLKRRLASVASSEQSEQPLKSTSSSSINFVSGGLAAGLATAITNPFDAVKTRLQLMPGKYGNMIRAVRLMIREDGVRSLFGGLGLRITRKALSSALAWTVYEELILRAEAHWAEKDKIDL",
    "output": "Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRAYIYDEESQLSPQDEHESSQSVSKQELEKLGVLYWSIDSIDQVNSIAIQRDYKNRDQIICSPQAMGDIYQQKLDTFFEEHLHEDEEIRWVVEGSGYFDVRDQTDQRWVRIKVEKGDLLVLPPGIFHRFTVDKDNYIKAMRLFKDEPKWVALNRSTESESNPYRKAYIEQVGKAMTMGAF",
    "output": "Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKITNITTYRLPPRWMFLKIETDEGIVGWGEPVIEGRARTVEAAVHEFGDYLIGQDPARINDLWQVMYRGGFYRGGPIMMSAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPAEVIDGIKKLRGIGFDTFKLNGCEEMGIIDNSRAVDAAVNTVAQIREAFGNEIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPRLAAQTHIPIAAGERMFSRFEFKRVLEAGGVAILQPDLSHAGGITECYKIAGMAEAYDVGLAPHCPLGPIALAACLHVDFVSHNAVFQEQSMGIHYNKGAELLDFVKNKEDFNMEGGFFKPLMKPGLGVEIDEARVIELSKNAPDWRNPLWRYEDGSVAEW",
    "output": "Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRQALPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARSEIPADAIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKALARVLVDGNKARTTRQRLTLFSRLRLRDLLPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWAEGKLAEEVMTTYVPPYKNPFAEDNNIRGASTLADYAKLRPAFDRKHGSVTAANSTPLTDGAAAVIMMTESRAKELGLRPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTMADLTLFDMHEAFAAQTLANLQLLGSERFAREVLGRAQATGEVDDAKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE",
    "output": "Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAMTVHCDIVSAERQLFSGLVEIVVASGVEGDLGIMPGHAPLLTRLKPGPVRVKKQNGEEEVFYVSGGFLEVQPKLVTVLADTAERAENMDAAEAERAKARAKEALEGKSSEMDYSRAAATLIEAVAQLRAIQQLKNKR",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSEAPESIETSPVVTPDVAESVQNQGVEVVQTEAPTEAQVVKTKSKKKRTKDPALYHTRKARIQVDPDSVNTDDRPPQTGTVYNIWFNKWSGGDKEDEKFNQKKADGRCSIARDSGYTRADKVPGSYFCLYFARGLCTQGHKCEFLHRLPVLTDMFSPTTDCFGRDRFFDYRDDMGGIGSISRVNRTLYVGRIHVSDAAKAGALDEIVSRHFSEWGDVDRIRVLHDKGVAFVTYATEVNAQFAKEAMAHQSLDSGEVLNVRWATQDPDPLAQAREQRRLEENAAEAIKRLLPQEYVDELEGRAKKSKPLLEGYEEDDSEKLKRIMNNQKEAGAEPAEEVKQIEPAPEPAAPVSTDTGMFNKSSLSALKALKKKKKTKAKVEE",
    "output": "Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLNVMDKFCWLYEKPTCQGQIKALPEHFIVKENLGFEFAGKGEHFMVKIRKVGENTKYVVNELAKACGVKSRDVSWAGLKDRHAVTEQWISVHLPGKADPDLTDFVAEHPGIEVLETTRHDKKLRPGDLVGNWFQIRLLDLTNPEELALKLEQVKMHGVPNYFGQQRFGHGGNNVIKARSWGNDEFRLRDKSKRSFYLSAARSWLFNMVLSTRIEQGSVNSLMVGDCLQNAGEDNCFLAESITEELQASIDKGLVNITAPLVGDNALPTAADAEAFELAIIANEPSLLKLICDNRMRHERRTLLLKPQEMEWQFDGNDVVLSFALPAGCFATSVVRELLVEQEGSTHANIDQ",
    "output": "Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSGGLLLLLGLLTLWEGLTPVSSKDRPDFCELPDDRGPCRGIFHAFYYNPDQRQCLEFIYGGCYGNANNFKTIDECKRTCAA",
    "output": "Serine protease inhibitor."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSGEVPPNINIKEPRWDQSTFIGRASHFFTVTDPRNILLTNEQLENARKVVHDYRQGIVPAGLTENELWRAKYAYDSAFHPDTGEKMTLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKRVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGTRLGESTNAAKQAITQVVISRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVTLVGFCLVFATPLCCALFPQKSSMSVTSLEDELQASIQRTHPEIRRVYFNKGL",
    "output": "Amino acid transporter importing serine, an essential substrate of the mitochondrial branch of the one-carbon pathway, into mitochondria. Mitochondrial serine is then converted to glycine and formate, which exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. May also transport other amino acids including alanine and cysteine."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDITASMVKELREKTGAGMMDCKKALTEAEGNMDRAVEVLRERGLAAVAKKSGRIAAEGLVESYIHGGRIGVIVEVNSETDFVAKNQEFKDFVKDVALHIAASNPQYVRREDVDPALVEKEKEILTKQALNEGKPEKIVEKMVEGRIDKFYKEICLLEQPFVKDPDVTVGDLLTEKISKIGENISIRRFTRYEVGEGIEKKEENFAEEVAKQMAQN",
    "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSELPDLSQIAPTLKAEILAEALPYIRQYHGKTVVIKYGGNAMTEERLKQGFARDVILLKLVGINPVIVHGGGPQIDQALKKIGKQGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVTLINHFGGHAVGLTGKDGGLIHARKMLMPDRDNPGQYVDIGQVGEVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLAVVLNAEKLVMMTNIPGVMDKEGNLLTDLSAREIDGLFADGTISGGMLPKISSALDAAKSGVRSVHIIDGRIEHSVLLEILTEQPFGTMIRSH",
    "output": "Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED",
    "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSRLRIFADTNPATPEFDSRDGDAIAAELVKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYAPKKPHKAS",
    "output": "Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSGTELLWPGAALLVLLGVAASLCVRCSRPGAKRSEKIYQQRSLREDQQSFTGSRTYSLVGQAWPGPLADMAPTRKDKLLQFYPSLEDPASSRYQNFSKGSRHGSEEAYIDPIAMEYYNWGRFSKPPEDDDANSYENVLICKQKTTETGAQQEGIGGLCRGDLSLSLALKTGPTSGLCPSASPEEDEESEDYQNSASIHQWRESRKVMGQLQREASPGPVGSPDEEDGEPDYVNGEVAATEA",
    "output": "Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEKYIKEHTLKPNEIERYGRQLITPDIGVSGQMSLCNSSVLIIGAGGLGCPVALYLSSAGIGTLGLVDYDTVEISNLHRQIGHRESSKGISKAVSLSKTISELNSLIKVNTYETTFTSETAMEIIKNYDIVVDASDNVATRYLVNDACVLTGKPLVSGSALKWEGQITCYNYNNGPCYRCIFPTPPPVETVTKCSDGGVLGPIVGVIGSLQALEVIKILTNNKEGVLSGRLLIYDGMSAVFRTVRIRGKQSGCNVCGDKPTVTQLIDYTQFCQSNYSESAGKVDDRVDKTLIITVEQFNQSIKNNNNNHLLIDVRPKIQFDICSLPNSNNIPIEEIDKKESIEIIEKLIKEKVENNNNNNNNNENRDASDELSVYLVCRRGNKSQDAVKILDEKLKEFRDKFKLLHIKDGLLGWNESIDDSFPIY",
    "output": "Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and mocs2a. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSTESMIRDVELAEEALPKKMGGLQNSRRCLCLSLFSFLLVAGATTLFCLLNFGVIGPNKEEKFPNGLPLISSMAQTLTLRSSSQNSSDKPVAHVVANHQAEEQLEWLSQRANALLANGMDLKDNQLVVPADGLYLIYSQVLFKGQGCPDYVLLTHTVSRFAISYQEKVSLLSAIKSPCPKDTPEGAELKPWYEPMYLGGVFQLEKGDLLSAEVNLPKYLDITESGQVYFGVIAL",
    "output": "Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance (By similarity). Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6 (By similarity).; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKEIIIWSAYLDAEKSRKEGRKIPKELCVNNPKIKDIYNSLRKLGYNAEIVKNKCHPKEWWEIVGYIKVKVNDDIPKLEILKKICENLKK",
    "output": "Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDSYEKEESVASTSGIQDLQTLSELVGPENAGEGELTIAEEPEENPRRPRRYTKREVKCVSYHAYKEIEDKHPQHIKLQDWIPTPEEMIAQKVQNQDLGTILSFDVTCLKSITSLGRNDPGDDPSIMSHVLPVVTPWPMSQDHYAPTLFGILDRYYQGYLKSPATYQTWKFTCQVDPSGKRFMETQFWVPPLGQVNIQFYKNYQILTCCQAVDPFANIFHGTDEEMFDIDSGPDVWCSPSLCFKVIYEGAMGQKQEQKTWLCRLGHGHRMGACDYRKVDLYAMRQGKENPYGDRGDAALQYAYQVKRGCKAGCLASPVLNYKALQFHRTIMADFTNPRIGEGHLAHGYQAAMEAYGPQRGSNEERVWWNVTRNQGKQGGEYYREGGEEPHYPNTPAPHRRTWDERHKVLKLSSFATPSDIQRWTTKALPYGWKVVTESGNDYTSRRKIRTLTEMTQDEIRKRWESGYCDPFIDSGSDSDGPF",
    "output": "Bet counteracts the innate antiretroviral activity of APOBEC3 family defense factors by inhibiting their incorporation into virions. May be implicated in the establishment and/or maintenance of viral persistance. Bet is required for viral replication (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQELEERIQSEGTVKAGNVLKVDAFLNHQCDVRLFDRMGSAWAAHFAGKHITKILTIEASGIGIACVAAQHFGNVPVVFAKKAQSINLDGDQYTTTVYSFTKQKEFPVIVAKKYLNAGDHVLLIDDFLANGKALRGLIDLCEAAGATVEGIGIAVEKGFQGGGDALRAEGYDVDSLAIVESMNPETGEITFRH",
    "output": "Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPNGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK",
    "output": "Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFPMVTEFMNYGQQTIRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVRSPVSDKFCIPDTLASWPYPRILNPHYAEEKAASAAWTKGFGAFGPKAQDAFDRCDFNLLACLAYPIATPERCRSGCDLMNLFFVIDEHSDTHGEETVRKMKDVVMDAIRNPHKPRPNDEWIGGEIARQFWERAMCYASEISQRRFIDTFDEYLESVVDQAADRDSARIRDIESYINIRRNTIGAKPSFVIMEQGMDIPDNVFENEVFQRLRMATIDMLCLGNDIVSYNIEQARGDDSHNIVRIVMNELDTDVPRAMDWVAQRHTQLEREFFTALSELPTWGEPIDGWVKEYVYGLGNWVRANDQWSFESQRYFGTKGMEIMKSRWLSVLPKVRPAEVGPQLVDQSLL",
    "output": "Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to delta(6)-protoilludene . In presence of Ca(2+), a significant switch from 1,11 to a dual 1,11/1,10 cyclization occurs, producing beta-elemene as the major product, with lower levels of delta(6)-protoilludene and (E)-beta-caryophyllene, and traces of beta-selinene and alpha-selinene ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKNVPYLSAVGAIMYLMVVTRPDLAAAVGVLSQFASDPCPTHWQALKRVLRYLQSTQTYGLEFTRAGTAKLVGYSDADWAGDVESRRSTSGYLFKLNGGCVSWRSKKQRTVALSSTEDEYMALSEATQEAVWLTVRTRRTKG",
    "output": "Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSSYSQLFAQHLDTLQQRTRDILQQQGLSGLAIHSGQTHRIFLDDQDYPFKVNPQFKAWLPVLDNPHCWLLVDGVNKPVLLFYRPVDFWHKVAELPNAFWVDFFDIRFLTRPEQVADHLPANKQEWAYLGGHLEVAELLGLGQPNPEAVLNYLHYHRAYKTAYELECLRDANRIGVRGHIAAKDSFMAGASEFEINLAYMKAVGQGANEAPYGNIVAINRNAAILHYTHLSAQRVPDAERYSFLIDAGVDVHGYASDITRTWAWRRGEFADLIAALDAQQQEIIEEIKPGRRYSELHLQMHHRLARLLQATELVDMSVDEMIHTGVTNVFFPHGLGHFLGLQVHDAGGFMQDERGTHLSAPEQFPYLRCTRVMEVGQVFTIEPGLYFIDSLLEPLRLGEQGKRVNWNKVEALRPYGGIRIEDNVVLHANGVENLTRQAGL",
    "output": "Splits dipeptides with a prolyl residue in the C-terminal position."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSGNRGGSYISGIVPSFKERRPFHERQKDVEEIRSQQPNKVPVIIERFDGERSLPLMDRCKFLVPEHITVAELMSIVRRRLQLHPQQAFFLLVNERSMVSNSMSMSNLYSQERDPDGFVYMVYTSQPAFG",
    "output": "Ubiquitin-like modifier involved in the formation of autophagosomal vacuoles (autophagosomes) . When lipidated mediates tethering between adjacent membranes and stimulates membrane fusion . Less effective at promoting membrane fusion than lgg-1 . Acts upstream of the autophagy protein epg-5 in the aggrephagy pathway, which is the macroautophagic degradation of ubiquitinated protein aggregates, and preferentially interacts with autophagy proteins and substrates containing LIR motifs to mediate autophagosome formation and protein aggregate degradation . In particular binds to components of an atg-5-lgg-3-atg-16 complex to regulate autophagosome formation and cargo sequestration . Required for the degradation of specific sqst-1-containing aggregates during embryogenesis and the early stages of larval development . Involved in allophagy, which is an autophagic process in which paternal mitochondria and organelles are degraded during fertilization, and moreover is required for the degradation of lgg-1-positive allophagic autophagosomes in embryos . Involved in xenophagy, the autophagy-mediated degradation of pathogens and pathogen products, such as toxins . Also plays a role in membrane-pore repair . Through HOPS complex subunit vps-39, tethers lysosomes with autophagosomes to form autolysosomes . Plays a role in the distribution and clearance of germ cell specific P-granules from somatic cells to ensure exclusive localization of the P-granules in germ cells . Essential for dauer development and life-span extension ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTRMAEKPISPTKTRTRFEDIQAHYDVSDDFFALFQDPTRTYSCAYFEPPELTLEEAQYAKVDLNLDKLDLKPGMTLLDIGCGWGTTMRRAVERLDVNVIGLTLSKNQHARCEQVLASIDTNRSRQVLLQGWEDFAEPVDRIVSIEAFEHFGHENYDDFFKRCFNIMPADGRMTVQSSVSYHPYEMAARGKKLSFETARFIKFIVTEIFPGGRLPSTEMMVEHGEKAGFTVPEPLSLRPHYIKTLRIWGDTLQSNKDKAIEVTSEEVYNRYMKYLRGCEHYFTDEMLDCSLVTYLKPGAAA",
    "output": "Involved in the biosynthesis of hydroxymycolate, a common precursor of oxygenated mycolic acids (methoxymycolate and ketomycolate). Probably transfers a methyl group from the S-adenosylmethionine (SAM) cofactor and, subsequently or simultaneously, a water molecule onto the double bound of ethylene substrates, leading to the formation of the hydroxylated product at the distal position."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLDFLAITLSGKPPQVIQGETVNLKWQWLGEGILTLVPHRSYTQSVVISAGIHGNETAPIEILNQLVTDLLAGQLPLSVRLLVLLGNPPAIRKGKRYLSNDINRMFGGRYQHYTPSDETRRASTLEQRVMAFFQASHTSERLHYDLHTAIRGSYHPRFGLLPYQQTPYSAAMFRWLRDIELDALVMHTSAGGTFAHFSSERCQAASCTLELGKALPFGENQLSQFSAITQGLRSLVSDSALPARKTENMKYYRVVKSLLRQHPDFKLRVAEDTVNFTRFAQGTLLTEQPNDNYRVEHPYEWILFPNPHVALGLRAGMMLVKMCESELPIT",
    "output": "Transforms N(2)-succinylglutamate into succinate and glutamate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDYQTFEKVNKFINVEAYIFFLTQELKQQYKLSLKELLILAYFYYKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSRNEADERRIFVSVTPIQRKKIACVINELDKIIKGFNKERDYIKYQWAPKYSKEFFILFMNIMYSKDFLKYRFNLTFLDLSILYVISSRKNEILNLKDLFESIRFMYPQIVRSVNRLNNKGMLIKERSLADERIVLIKINKIQYNTIKSIFTDTSKILKPRKFFF",
    "output": "Positive regulator of RNAII and RNAIII in a cell density-dependent manner. It can contribute to the expression of virulence genes controlled by agr. May also regulate target genes via an agr-independent pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASLADRVRGNGRIAAGLLLNLLVSICIVFLNKWIYVHYGFPNMSLTLVHFVVTWLGLYVCQKLDIFAPKSLPPSKLLLLALSFCGFVVFTNLSLQNNTIGTYQLAKAMTTPVIIVIQTLCYKKTFSTKIRLTLIPITLGVILNSYYDVKFNFLGTVFAALGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAMLLVAVPFFEPVFAEGGIFGPWSVSALLMVLLSGVIAFMVNLSIYWIIGNTSPVTYNMFGHFKFCITLFGGYVLFKDPLSINQGLGMLCTLFGILAYTHFKLSEQEGSKSKLVQRP",
    "output": "Putative transporter."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFKENTIKLGIAPIAWTNDDMPELGAENTFEQCISEMALAGFNGSEVGNKYPRNTVVLKKSLELRNLEIASAWFSTFLTTKPIEETVEEFIKHRDFLHDMGAKVIVVSEQGHSIQGLMDVPLFKNKPVFTEEEWDKLADGLHHLGKLAQEKGLHIVYHHHMGTGVQTTAEIEKLMDMTDPELVSLLFDTGHLVFSGEEPLYILKKYLSRIKHVHLKDIRQEVVDIVKENELSFLQAVKNGAFTVPGDGVIGFDKVFTILANSDYKGWFVVEAEQDPALANPFEYALKARKFIQEKAGL",
    "output": "Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTAGLLTAGDPDQVTFEDVVVDFTQEEWGHLEPAQRTLYRDVMLETFGLLVSVGHWLPKPDVISLLEQEAELWAADKGGPRGVCPDLETRPQSKLSTENQGVTEEIPNSALVERFLQESLWHSKDEGAAGHREQGPEKSDSCVVQAACTLVKTLTEEQQQGDGCGENLSLRPDLPTQPMTPERQGAPTWGTHGQRENPDSNAQQKTCAKEKPYGCQECGKAFSHSLALIEHHRTHTGERPYECPECGKGFRNSSALTKHQRIHTGEKPYKCAQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGEKPYTCSQCGKAFRQSIHLTQHLRIHTGEKPYQCGECGKAFSHSSSLTKHQRIHTGEKPYECQACGKAFTQITPLIQHQRIHTGERPYECSECGRAFSQSTLLTEHRRIHTGEKPYGCNECGKAFSHSSSLSQHERTHTGEKPYACSQCGKAFRQSTHLTQHQRTHTGEKPYECSDCGKAFSHSSSLTKHQRIHTGEKPYECNECGKAFSQLAPLIQHQRIHTGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTGEKPYDCQDCGKSFRQRTHLTQHQRIHTGEKPYECRDCGKAFTHSSSFIKHQRTHTG",
    "output": "Plays a role in the regulation of cell morphology and cytoskeletal organization. May be involved in transcriptional regulation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "TNTPEQDRYLQAEKYIEFYVIVDNRMYRYYNYDKPAIKIRVYEMINAVNTKFRPLKIHIALIGLEIWSNEDKFEVKPAASVTLKSFREWRQTVLLPRKRNDNAQLLTGINLNGTAVGIAYPGSLCTQRSVFVVQDYNRRMSLVASTMTHELGHNLGIHHDEASCICIPGPCIMLKKRTAPAFQFSSCSIRDYQEYLLRDRPQCILNKPLSTDIVSPAICGNYFVEEGEECDCGSPAACQSACCDAATCKFNGAGAECRAAKHDCDLPELCTGQSAECPTDSLQRNGHPCQNNQGYCYNGKCPTLTNQCIALLGPHFTVSPKGCFDLNMRGDDGSFCRMEDGTKIPCAAKDVKCGRLYCTEKNTMSCLIPPNPDGIMAEPGTKCGDGMVCSKGQCVDVQTAY",
    "output": "Snake venom zinc protease that inhibits hemostasis by binding and cleaving the vWF in humans. Has also and inhibitory effect on the collagen-induced platelet aggregation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQWSDEGLVLGARRHGETSVVLELMTAGHGRHLGLVHGGRSRRMQPVLQPGNRVRAVWRARLDEGLGHFAVEPIESAAGRLMGSRLALYGLAHAAALLRLLPERDPHPSLYAAAQVLVAHLTDPAIAPALMVRFELAVLADLGFGLDLSACAATGSNAYLAYVSPKSGRAVSAAAGEPWRDRLLALPDFLVAREAGGTGATPTPRDVRQGFTLTGYFLDQHVWHPRGVAPPEARELFVALGTADAG",
    "output": "Involved in DNA repair and RecF pathway recombination."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA",
    "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRVVEGTPFECLKDTFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA",
    "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKKSNNNLTLYKGYINREDRERLHGHKSFVIWFTGLPASGKSTIAHLVEKELYKRGCSTYVLDGDNVRYGLCSDLGFSIEERKENIRRVGELVKLFVDAGIIVITSFISPFKEDREKVRSLFKEEDFIEVYTKCPVETCSLRDQKGIYKKAIKGEIKNFTGISAPYEEPENPEITIFTDIDSPIEACQKILRYIKDKLKL",
    "output": "Catalyzes the synthesis of activated sulfate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGVSIVLGSQWGDEGKGKITDMLAQQATLCCRAAGGHNAGHTIVHGNKTYDFHILPSGLISPSCINLIGAGTVVHVPSFFKELASLEEKGLEGASKRIFISDRAHVCLQLHSVVDGLEEAKLGGRKVGTTGKGIGPCYSDKASRRGIRVGEILDEAVFERKLRSLDAGYRARFGDLEYNVEEELAQFKEYRKLLGPYIVDQLAFLQKYKDSPNTLVEGANALMLDLDHGTYPYVTSSSTGLGGAMQALSLNPTSIKSVIGVVKAYTTRVGSGPFPSEQFNADGDKLQSVGREFGVTTGRRRRCGWLDLVVCRYSQAINHYTALNLTKLDVLDDFDEIKVGVAYILPDGTRTENTIPADAEVLEKVKVEYVTLPGWKSNTMGVKKYEDLPDNARAYIEYIERELGGVPVKWIGTGPARDDMIARE",
    "output": "Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MENNTAVLGAGFSWGFKSDNVMKCQEQEEQQARENEKSLNSMVANLVQAQGMDPKGRKRRLDEPTNPQPQMMVPPRKYNVSKRRPHHSTISGQPLPLHRGLELMSKDQLQYILIEVMKNYPISQQLVQNKLVDFNFSIEKCEILLKEKLQQLHESIPYSRSHDYQRLSDYAFVRMKPHILEFLNCLVDCVLDRIPPRVDNLHESLKILDMTTDMVTKLPRFQLASNNYYYDKCLEQLACLWCTVIEHIARDVIMTVNDAPLLRNWIQKLELYNELCHGILTKPLNQFKSLAVVDAGVTDSNSTKGTNATRNRWSGSTDNYTVGDNQ",
    "output": "Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSITKDQIIEAVASMSVMEVVELIEAMEEKFGVSAAAAVMAGPAAAEAVEEKTEFDVVLTAAGANKVAVIKAVRGATGLGLKEAKDLVEAAPANLKEAVSKDEAEALKKELEAAGASVEIK",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVHLKALASGTLFASLASSAVISRQAAASINDAFVAHGKKYFGTCSDQALLQNSQNEAIVRADFGQLTPENSMKWDALEPSQGSFSFAGADFLADYAKTNNKLVRGHTLVWHSQLPSWVQGITDKDTLTEVIKNHITTIMQRYKGQIYAWDVVNEIFDEDGTLRDSVFSQVLGEDFVRIAFETAREADPNAKLYINDYNLDSADYAKTKGMVSYVKKWLDAGVPIDGIVSLLPPRDEGLTSCTALTALASTGVSEVAVTELDIEGASSESYLEVVNACLDVSSCVGITVWGVSDKDSWRSSTSPLLFDSNYQAKDAYNAIIDAL",
    "output": "Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGIILCEFINKLQPGSVKKVNESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKTKGNKVNVGVKYAEKQERRFEPEKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLNPEYPELSEPTHNHHPHNYYNSA",
    "output": "Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNLQRLSIFGTDNIGVYIYTNNKYTVVPRGLDSETKENIVQILGTELIEAEISRSFLLGIFISGNDNGILLPKSTIDDEFRFLKENLRDCRVEVLNSKVTALGNTILTNNKAALIYPEFNDIEEKIIKETLGVEEIRRGKIAQMITVGSVGVVTNKGGLVHVDTSEKELKELEKLFSVKIDIGTVNFGSVFIRSGLVANDKGTLVGASTTGPEILRIQKALGE",
    "output": "Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEILGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRSEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHYARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR",
    "output": "Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALPLSGTRHLTRALLSNVTLMAPPRIPSSVHYGGSRLGCSTRFFSIRCGANRSGSTYSPLNSGSNFSDRPPTEMAPLFPGCDYEHWLIVMDKPGGEGATKQQMIDCYIQTLAKVVGSEEEAKKRIYNVSCERYLGFGCEIDEETSTKLEGLPGVLFVLPDSYVDPENKDYGAELFVNGEIVQRSPERQRRVEPQPQRAQDRPRYNDRTRYSRRRENTR",
    "output": "Involved in plastid rRNA processing and consequently in translation and early chloroplast differentiation . Involved in organellar RNA editing. Required for the processing of multiple editing sites in plastids ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MARTRNRFDRTPFQTAITDLSHDGRGVARRDGEGGKVTFISGALPGELVRAEPTARSRHFDEAKTVEVLEASPQRVAPRCPHFGVCAGCVLQHLEESQQIVAKQRVLMDNLERIGHVTPQAVLPGLTGDNWGYRRKGRFSVRRVEKKAKTLVGFRELDPRFVADLSVCYTVIPQIGEKIPLLAALVEGMDGKRDIPQIEFIAGDDAVALTIRHMQPLSARDQQAWIAFAQEHGFAIFLQPGGVDSVHPLWPQEVPLSFRLPQWDVDLAFRPLDFIQVNASLNQKMIVHALALLDAKPDDRVLDLFCGLGNFTLPLARVVREVVGVEGDAGLVARAKDNAQRNGLDNAQFYAADLTQDQRNAAWMRQGFDKLLLDPPRSGALEVLQQLPLKTFERIVYVSCHPGSLARDAGYLVNEQGFTLVSAGAMDMFPHTAHVESIAVFERR",
    "output": "Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDTAFVKDFIDNLLENDGLKLKRAIGVGIFLFNKLKEDAPDYILESLKEVDKLPFEKKKAVLREVRKFLSEYEKRKKEGNFLEKTKRKPIDVFFNPIEKVKILTKTQISTLKALGIETVYDALFYFPEKYEDKRLNTSIKTAKVGEKVALKVKVKEVKIKENERYTLEVVCTDGTGYITLKYRYKNPHFALKAFRKGMEIVVYGKLKSFKGEKYMVHPEVKSPSSEELGKIIPVYYVRKRGELQEISSKTKQKRVRTALTALSESLYRYFPEYMPDYLIEKYNFPDIALCIKELHNPKDISVNALNSFTDLYHKRVIYDELFLFQLALLLKKQEIKKEKAPKVNVDEKFLRKAIEKLPFKLTRAQERAIKEILEDLSRDVPMNRLLQGDVGSGKTIVAILTSLAVVKSGYQVAVMVPTEILAHQHYKKFSEMLKDYGVNVALLTGSLTPSQKKSVYKHVKEGNIHVLVGTHALIQDKVEFKNLGYVIIDEQHRFGVMQRKLLLEKGKGLYPHCLVMSATPIPRTLALSIYGDLDISIIDELPPGRKEVITKLYFESQKEEVYKKVEEELKKGNKVYVIYPLIEESEKLNLKAATEEYERWKKLFPDRKVLLLHGKMPDKEKLAVMEEFKREGDILVSTTVIEVGIDVPEATVMVIEDAHRFGLSQLHQLRGRVGRSDKEAYCLLVVPDEIKNEKNESLKRLRVFVKTTDGFKIAEEDLKLRGPGEIIGVSQSGYFGFRVANLARSQDRALLGVARKDAEELLKNNPNLENLQDLKKLLIKKYGDKMELSFVA",
    "output": "Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "DRPRPARLSHARFSKNHSGRTHSMKDKAGRKHRPLDVFDFPDHSQLSSFSRLGENEKDEESYETFDPPLHSTAIYADEEEFSKQCGSHLPSTPQEKEAKRSSDTSEIEASENESVKISAKKPRRKLKPISDESESPEESDVRRKVKPTENISTQHEAVSATALPGLSEKPAEAVTPQKTGPQSAESSAEKATLATEHQLETQKNKMLPGKRKKPRSYTTDTSDCAPVWCLKEKKASEIMELDVFLSAFENILLEYEQKIDSRVCKAAINKFHSNLKEELIKMVQEIQMLKTLKRKNAKIISNIEKKRQRLIEVQDELLQVEPELKQLQIKYEELQERKASLRKAAYFLSNLKQLHQDYSDVQEEEPSVKETYDSSSLPALLFKARPLLGAEHHLQNINYQLENLLDQK",
    "output": "Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKNTTNTKRTKFIFVTGGVLSSLGKGLAAASIGALLESRGLSITFQKLDPYINVDPGTMNPFQHGEVYVTDDGAETDLDMGHYERFTNAVMGQKNNFTSGRIYHTVINKERRGEYLGGTVQVIPHITDEIKKSVRQLDGSVDIAIIEIGGTVGDIEGLPFIEAIRQLRGDLGRDYTLFIHLTLVPYIKTAGEVKTKPTQHSVRELRADGIQPDILVCRTEVPLEENIKAKIALFCDVQQDAVINCVDVDSIYKLPIALHAEGLDSKILELLNIWTANPNIKPWQDLVENIQNPKNEVTIAITGKYVDLTEAYKSLHEALIHGGLANHTKVKLRYVSAEDLESGDPDSYLKGCDGILVPGGFGRRGVEGKIKAITYARENRIPFFGICLGMQLAVVEFARNMAGMSEAHSTELEPNSPDPVIYLTKEWFDYRTNKIQRRDENSDLGGTLRLGAYPCVLQQESHAGDAYGTQEVFERHRHRFEFNNDYRQQLIEKGLVISGTSPDGDLVEIVEIEDHPWFVGCQFHPEFKSKPMQAHPLFRDFISAAVANKKG",
    "output": "Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKSFELEADGLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVEKLDRLNARA",
    "output": "Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTTTLPAYDEVVARYEPVIGLETHVELGTNTKMFCGCPTDFGGAPNTRVCPVCLGLPGSLPVANRAAVEATIRIGLALNCSIAEWCRFARKNYYYPDMPKNYQISQYDEPLCVDGYLDVEVDGEPVRISIERVHMEEDTGKTLHVGGATGRIHGATESLVDYNRAGIPLVEIVTKPIPGAGAMAPEVARAYVTELRDVLRSLGVSDVRMEEGSLRCDVNTSLNLPGEQWGTRTETKNVNSLRSVERAVRSEMIRQASVLEGGGRITQETRHFHEDTGDTTSGRSKETATDYRYFPEPDLVPVAPDPTWVAELKAALPELPRLHRRRLQQEWGLSDLDMQSILNAGAVELIEATIAAGATPTAARKWWLGELSRRANEAGVELADIGATPEQVAELQGLVDAGKLTDKLARTVLEHVVAGEGSPAKIMADRNLEVVSDTGALTAAVDEAIAANPAIADKVRGGKVAAAGALVGAVMKTTRGQADAKTVRELILERLGVQG",
    "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSGSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQQHAKGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHIGQMLLTRADLEDRERFLNARDTMNALLDNRIVPVINENDAVATAEIKVGDNDNLSALAAILASADKLLLLTDQAGLYTADPRNNPEAELIREVHGIDDVLRGMAGDSVSGLGTGGMATKLQAADVACRAGIDVVIAAGSQVGVIADVIDGTPVGTRFHSLETPLENRKRWIFGAPPAGEITVDDGAVFAIMERGSSLLPKGIRSVKGDFSRGEVIRIRNLNGRDLAHGVSRYNSDALRMLAGHHSQQISEILGYEYGPVAVHRDDMIVS",
    "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MESYIQNLFAERIGGKSFGKEDVIYKFEKIKRAKQAAKLKYPDMELIDMGVGEPDEMADESVVEVLCEEAKKHVNRGYSDNGVQALKDEIPIYLEKIFGVKDLDPVNEVVHSIGSKPALAYITSVFINPGDVTLMTVPGYPVTATHTKWYGGSVETLPLLEKNNFLPELDAISKEVRENAKILYLNYPNNPTGAQATKKFYKEAVDFAFENDLIVIQDAAYAALTYGDKPLSFLSVKDAKEVGVEIHSFSKAYNMTGWRLAFVAGNELIVRGFAAVKDNYDSGQFIPIQKAGIHCLRHPEITEKTRAKYERRLSKMVKILKEAGFNAKMPGGTFYLYVKAPIGTKDGAKFANAEEFSQFMIKEKLISTVPWDDAGNFVRMAACFEAFKDGEISIEEEDRILNEVKRRLTEVEFVFE",
    "output": "Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIDTDGYRPNVGIIICNNNAQVLWAKRFGQHSWQFPQGGIKEGETPEQAMYRELYEEVGLKPEHVKLLATSRHWLRYKLPKRLVRWDSPDPVCIGQKQRWFLLQLISDEQQIEFEACGNPEFDAWRWVTYWYPVRQVVSFKCEVYRCALKEFSAVAFSLMKKSSDKKRNKRPRRASFYKKR",
    "output": "Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVVILEHEIPQGSQLYFGKSARLKRRIEERASQILYTAGFEEIITPSFSFLEHQRDTSSREVLRLSNEKNHQIALRNDTTLDVVRIITKRLGRSTEHRRWFYIQPVFSYPTNEIHQIGAESLGEADAKSMLKVAIEIFRSLELEPILQLSNMRIPLLCAEHSRLGLEVFAKMQVEKIMASEEYLGELLQIKNAQDLQRVTSKVPSFLKEELEKLRALAEGIEYPRFVFAPLYYAPMDYYNGIFFRMFEGNSTLLSGGIYEMDELQSCGFGLYTDQLIEKILRHNEG",
    "output": "Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIKNEQPPLSFEEAMEQLEEVVEQLEQGDVPLEEAISMFQKGMNLSKVCHEKLATVEKQMDQILKEDGNFEETVLQEEQE",
    "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKILLIGPPGSGKGSVSELLTKNNTLKHVSTGNLFRAILKEDSELARKIKEINVSGGKLVPDEITNQVAKSAIDELIKNEQSFILDGYPRTINQALALEQYCNLDYIFYLDIDHQELMKRLTGRWMCPKCAGIYNIHFKKPQVHGLCDNDQATLYQRADDHADAVSIRLDEYDKLTLPLIKHYETNPRFIKINANQPIEDVYKNINNYLKQNK",
    "output": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATYVIGDLQGCLTPLVQLLEQINYHPEQDKLWFAGDLINRGEESLETLRFIKSLGNNATVVLGNHDLHLLAVSHGYGKLKRGDTLAEILTAGDRDDLMDWLRHQPLFHYDEQLNTVMTHAGIPPCWDLQKAQTLAKEVEDKLKSDSVDEFFATMYGNKPNTWSDDLTGLDRLRAITNYLTRMRFCDENSKLDLESKEGINTATKGYAPWFNYPTKVPEDCHIVFGHWAALEGKTQKERIHALDTGCVWGGSLTALRLEDQQRFSTPCSINRKNP",
    "output": "Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEKLLHWTIAQQSGDKAALEKIGEPDQKALNQLFGGPDEATLMKESIKVVESTDVSLEDKEIALENFEMLIENLDNANNIGNLKLWNPLIDILAKEDTPVELKVLICGIIGTAVQNNPKSQEDFNETEGLSELIELAQDDKKFELQSKALFAISSFIRNFQPGYAKFEKLQGLKLINFDNKNNKYQLRILSLISSILSNGLDDSLKAQFKEAKLPHYLASVLNEDSNTSLVDKSLNIVSQLNQLNYEFSLEEKYEINRGIQVVEGLSEKLNIDDLNNAKQATSS",
    "output": "Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRLIPLKAAAQVGKWAAAHIVKRINEFQPTAERPFVLGLPTGGTPLATYKALIEMHKAGEVSFKHVVTFNMDEYVGLAADHPESYRSFMYNNFFNHIDIQEENINLLNGNTDDHEAECKRYEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRIKTLTEDTRIANSRFFDGDINQVPKYALTIGVGTLLDAQEIMILVTGHNKALALQAAVEGSVNHLWTVSALQLHPKAVIVCDEPSTQELKVKTVKYFTELEAKNIVGF",
    "output": "Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPQQNYLDELTPGFTPLLAIKEASRCLLCHDAPCSQACPAQTDPGKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQRGCTRSGIDKPIDIARLQRFITDFEQQTAMQIYQPGSKTRGKVAIIGAGPAGLQASVTLTHLGYDVTIYEKQPQPGGWLRHGIPAFRLPQSVLDQEIARIVEMGVNIKCNCDVGGSLSLAQLKAEYRAVLMTVGMSCGSDLPLFEQASHVEIAVDFLQRARQADGDISVPRSALIIGGGDVAMDVASTLKILGCPSVTCVAREELAEFPASEKEFTSTQALGVSIIDGFTPVAVSGNKVTFHHVRHSGELTLEAENIILAVGQHARLDNFAEIKAQHNIIDTHNYQTDDPAIFAAGDIVKGDKTVVYAVKTGKEAAQAIHHYLEEACSC",
    "output": "Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSYLIPYVIEQTNRGERSYDIYSRLLKDRIVFLGTPIDDQVANVVIAQLLFLESEDPDKPVNLYINSPGGSVSAGLGIYDAMQHIKSPVNTTVVGMAASMAALLLAAGTGKRYALPNARVMIHQPHLSGVGGQVTDIEITAREAVKTKQLMAEILAKHSGQSVERILADTERDRWMSAQEAVEYGLVDEVLHPREKASRSAR",
    "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTKEQIIEAVKSMTVLELNDLVKAIEEEFGVTAAAPVAVAGGAGEAAAEKTEFDVELTSAGAQKIKVIKVVREITGLGLKEAKELVDNTPKVIKEAAAKEEAEEIKAKLEEVGAAVEVK",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MELFHHIKSVRDALGKARAAGKTVGFVPTMGNLHNAHLALVQQAKQHCDVVIVSIFVNRLQFGLNEDWDKYPRTLQDDAAKLREIGCDYLFCPEEGEVYPNGMDAQTRVIVPSMANVLCGASRPGHFEGVTTVVTKLFNIVQPDIAVFGIKDYQQLAIIRRMVEDLCIPVEIMAGDIVREADGLAMSSRNGFITAQERPRANQLNQSLNWVKQAILDGRRDFDVLESEAKKQIETAGFRPDYLSISNSKTLEPAANDDTDITVLGAMYTEAARLIDNVSLSVVN",
    "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MWRLIIIAILFQGLVNSAMLERRKRGVDPETAMNISEIILFRGYPSEEYEVVTGDGYILCLNRIPYGKISQKTKEPKPAVFLQHGLLADGSNWVTNLDYNSLGFALADAGFDVWLGNSRGNTWSQKHINYTIKQKEFWMFSFNEMAMYDIPASVNFVLNKTGQEQLFYVGHSQGTTIGFIAFSVLPELAKKIKMFFGLAPVMTVKFSSGGLVKLGELPEFLLKEIFGTKQIFPQNAVIKWLATHVCGQVLIDELCGNFFFLLCGFNEKNLNMSRVEIYSTHCPAGTSVQNMLHWSQAVKSGEVRAFDWGSRKENMAHYKQPTPPPYKMERMLVPTALWTGGHDWLSDRKDIAILLTLIPNLIYHKEIPEWEHLDFIWGLDAPQRMFRDMIQMMHKVQYAH",
    "output": "In physiological conditions, is crucial for intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. In venom, the biological contribution is unknown."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPDRLVPATLARRDDGILVSPEYGELPRDASRARAHANRMLAGTGLLARWQGRRTFTIVETGFGTGGRFLATWAAWRDDPARCERLHFVAIEAHPFTREDLRRAVSHLVADTTISENADALIDAWPMHVPGLHRLEFDAGRVVLTLAFGDARDMLQRLVARADAFYLGNVASAAHGDVLSADVIRALARIAADGATYATHSHDDTVKHALEQTGFTSRDVEDCAGEPALRVGEYAPRWRMRRHEPPRALPVAAREAIVIGAGLAGCAVVERLAARGWNITLIERHERIASEASGNPAGVFHPLMTRDDNVASRLTRSGFLHALARWRALEDAGHAFARSTRGMIHLAESADDFARMRDAFDALGAPSDYVSLLDTDAARAHLNLPVAHGGLLFPHGGAVWPAGVCAAQIAAAGERVTLLAGTEVARLERDRDIWRAVDAAGATLAEAPVVVLANAGDAVRLAGLRHVALQPVRGQLTLLPPGSTAPLPCPTIGDGYAVPLDDGTLLIGATFEPDDVDRTMRTVGHIENLARVRHLLPGLIGELPDVDTLRGRVAFRWVVADRVPVIGPLADEAQAVANARALSGAKARDLPRTAGLYGAFGYGSRGLVWAALGAELIASQLEGEPLPLERELVDAVDPARFLIRALRGRQIG",
    "output": "Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSAFTKIGLLGKADDRGTQLTLETITTALIHRGFALCLEARTAEQLNLPEEVETLSLPDLGEWAEIAIVVGGDGNMLGAARALCEYDIGVIGVNRGNLGFLTDLDPDEVMTPLLSVLNGNYHVEERFLLSAEVINNGSSSGTGRAINEIVLHSDKVAHMIEFELYVNDHFVFSQRSDGLICATPTGSTAYSLSGGGPILHPGLDAMTLVTMFPHTLSSRPIVVDGNSEVRLKAAFDNDLLQISCDGHVRMTVHPGDDVIIKKYPKALRMIHPIDHNYYHVLRNKLGWGSRLF",
    "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVQIVISSTGAEGLAEWVLMELQGEIEARYSTGLAGNLLGDLHYTTEGIPVLIVGHHILYGKTIHLEKPFAVLVKHTPGKQDCDEPGRGTGTQYLVTALIKNKILFKTRPKPIITNVPKKV",
    "output": "Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DSCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates POLH, which is suggestive of a protein network that coordinates DNA repair, recombination and chromosome cohesion reactions with replication fork progression (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTDQPNNDAVANEENGPQFSLQRIYVRDLSFEAPKSPAIFRQEWTPTVSLDLNTRQKQLEGDFYEVVLTLSVTVNNGDEVAFIVEVQQAGIFLIKGLDDGAMSHTLGAFCPNILFPYAREAIDNLVVRGSFPALMLAPVNFDALYAQELQRMQEAGETPTVQ",
    "output": "One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTERVQVGGLQVAKVLFDFVNNEAIPGTGVSADTFWTGAEAVINDLAPKNKALLAKRDELQAKIDGWHQARAGQAHDAVAYKAFLEEIGYLLPEAEDFQAGTQNVDDEIARMAGPQLVVPVMNARFALNASNARWGSLYDALYGTDVISEEGGAEKGKGYNKVRGDKVIAFARAFLDEAAPLESGSHVDATSYSVKNGALVVALKNGSETGLKNAGQFLAFQGDAAKPQAVLLKHNGLHFEIQIDPSSPVGQTDAAGVKDVLMEAALTTIMDCEDSVAAVDADDKVVIYRNWLGLMKGDLAEEVSKGGSTFTRTMNPDRVYTRADGSELTLHGRSLLFVRNVGHLMTNDAILDKDGNEVPEGIQDGLFTSLIAIHDLNGNTSRKNSRTGSVYIVKPKMHGPEEAAFTNELFGRVEDVLGLPRNTLKVGIMDEERRTTVNLKACIKAAKDRVVFINTGFLDRTGDEIHTSMEAGAVVRKGAMKSEKWIGAYENNNVDVGLATGLQGKAQIGKGMWAMPDLMAAMLEQKIGHPLAGANTAWVPSPTAATLHALHYHKVDVFARQAELAKRTPASVDDILTIPLAPNTNWTAEEIKNEVDNNAQGILGYVVRWIDQGVGCSKVPDINDVGLMEDRATLRISSQLLANWLRHGVISQEQVVESLKRMAVVVDRQNASDPSYRPMAPNFDDNVAFQAALELVVEGTRQPNGYTEPVLHRRRREFKAKNGL",
    "output": "Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTGGKWQDRVKSVEQRASSFQSSPLSCPYKPRLSQPWQPSSIWRLFPRQNAAIAFAQHIKQDVHIFSLEKEGSDAGQRIFLVTSYSELWHYYSTHRHSLMHCYEVILEGAVCKLYFDLEFHKASNKNLDGKMMVAKLIQYVCEKLEEVYGLHCSAKDVLDLDSSTSDKFSHHLIFMLPNAAFKDNSHVGRFIHDILHPALTNLKKSNPEAPGENRDDVEGTQAKRRKTEENDLGFLTVKNEKGQEQLFVDLGVYTKNRNFRLYKSSKLGKNAAFIVAEDNKFVPNPSKQITKDERIFLASLITNVSFTGQRILTYDMTQKSTAGSECPTLERESHSSDLLGDQKTSPFKEVDEFVLTLVCKDGIQGSIRRWNYFACEQLLVYDIEKFRWCHNVKRFHKSNNIIIVVDLKEEVWYQKCHDPECRRQNYRSSSFPLPQEVCMSHLLMEDEEDQAYLTDELGNIELAVTAPAESTSTTPSEDTEGWGDWPDDPAYLRALQEVEEEEEDEDEEVPDELLLQAVNECE",
    "output": "DNA primase and DNA polymerase required to tolerate replication-stalling lesions by bypassing them. Required to facilitate mitochondrial and nuclear replication fork progression by initiating de novo DNA synthesis using dNTPs and acting as an error-prone DNA polymerase able to bypass certain DNA lesions (By similarity). Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA (By similarity). Provides different translesion synthesis alternatives when DNA replication is stalled: able to synthesize DNA primers downstream of lesions, such as UV lesions, R-loops and G-quadruplexes, to allow DNA replication to continue (By similarity). Can also realign primers ahead of 'unreadable lesions' such as abasic sites and 6-4 photoproduct (6-4 pyrimidine-pyrimidinone), thereby skipping the lesion. Also able to incorporate nucleotides opposite DNA lesions such as 8oxoG, like a regular translesion synthesis DNA polymerase. Also required for reinitiating stalled forks after ultraviolet (UV) damage during nuclear DNA replication. Required for mitochondrial DNA (mtDNA) synthesis and replication, by reinitiating synthesis after UV damage or in the presence of chain-terminating nucleotides. In addition to its role in DNA damage response, also required to maintain efficient nuclear and mitochondrial DNA replication in unperturbed cells (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKNWIVGMVALVTMVPVMAATPWQKITHPVAGSPQSIGGFANGCVIGAQPLPLESADYQVMRSDQRRYFGHPDLLNFIHRLSAQTHQQQLGTVLIGDMAMPAGGRFSSGHASHQSGLDVDIWLQLPKQRWSQQQLLKPQPIDLVAVDGKRVIPALWQPQIESLIKLAAKDNDVTRIFVNPAIKKQLCLDAGADRQWLHKVRPWFAHRAHMHVRLRCPANSLECVDQDTPPPGDGCGAELESWFQPPPPSAKPGKTLPPPLPPSCQALLDNHFATE",
    "output": "Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSHIPVLLKETINALNIKKNGIYIDGTFGNGGHTKEILKYLGQSGKLYSIDQDIKSVNKGKKIKDKRFSIIFGKFSKKIPYIYKKNKKKKIDGILLDLGISSNQINQNDRGFSFMKNGLLDMRMNNTTGIPAWKWLKKSSQKEIEKVLRKYGEERYSKKISYAIYNRNKKKTITQTLDLVQIIKKAIPKIDKYKHPATRTFQAIRIHINNEIKELKKTLKISIKILKKKRRLVIICFHSLENRIVKNFFKKHGKTFFIPRGLPITEKKIKKIENKKIKIIKKIKPKKTEIQKNKRSRSAILRIAEML",
    "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEKREFKAESKRLLDIVINSIYTNREIFLRELISNASDAIDKVYYKTLGDSSLTFNKDDYYIKIKPNKEERTLTISDKGIGMTEKELDENLGVIAKSGSLQFKKENEIKDGFDIIGQFGVGFYSGFLVADKITVITKAFGADKAYKWESDGVDGYTISEAEKDSFGTDIILHLKANDEDENYDEFLEEYKLKSLIKKYSDFIRYPIKLDVTKSRVKEGTENEHEEYVEEETVNSMVPLWRRNKNELTDDDYNNFYVEKRFGFDKPLRHMHISVDGMISYNSILYIPENIPYDYYTKEYEKGLELYSNGVLIMEKCSELLPDYFGFVKGIVDSQDLSLNISREMLQHDRQLSRIAKNIKTKIKNELESMMKNDRESYEKFYKSFGRQLKYGVYDDFGMNKDELKDLLMFYSSKEKKMVSLAEYVERMAEDQKYIYYAVGESNERIEKMPQTEMVLDKGYEILYFTEDVDEFAIKMLMNYKEKEFKSVSSGDLGIESEEENKKENEENKGIFEAMKEALGEKISAVKASSRLKNYPVCLSSEGEVSIEMEKILSAMPNNQGVKAQKVLEVNTNHEVFNSLKDALENDKDKFNLYTKLLYNQALLVEGLSIENPVDFTNDICKLMK",
    "output": "Molecular chaperone. Has ATPase activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNKLFRSLAFYMLILVISVAIAVQLGGTSQQTTQLVYSDLVRYIQQGEVRSITLSGAYAEGELVSGEKFTVQLPPSSSQAPLVEMLQQHPNIKLDFRQDNTSGIWAMLLQTLVPVVLVLLAFFFIMQQTQGSGNRVMQFGKSRARLVTDDRKRVTFDDVAGIDEVKEELAEIVDFLKHPKRYLELGARIPKGVLLYGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKNSPCIVFIDEIDAVGRQRGAGYGGGHDEREQTLNQLLVEMDGFSANEGIIIIAATNRPDVLDPALLRPGRFDRQIVIDRPDLKGRLAIFQVHAKGKPLEPDVDLEVLAKRTPGFTGADIANLMNEAALLAARRRKKKISMQDVEDAIDRVLAGGPEKKSRVISEKEKRVTAYHEAGHAVVGHMLPHMDPLHKITIIPRGRAMGYTLFLPVEDRYNISKSEILDRMTMALGGRAAEEITFGEITSGAQDDIERTTQWARRMVTEWGMSEKLGPLTYGMKQDEVFLARDMTRLRNYSEEVAGLIDEEVRKFVHMAYQRAIDILTEHRDALEKVSEVLLEKETLEGKELQDLLEQLLPPRPKPEPLKPRMVGGGTSQVAPAF",
    "output": "Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSSYGGGGYSSRGGGGGYSGGYDRNGGGGGGYSGSNGYSGGGGGYGGGGYGGGGGGYGGGGGGYGGGYGGGGGDRMSNLGAGLQKQNWDLDTLPKFEKSFYQEHPNVAARSQAEVDKFRRDHAMTVAGNNVPSPVETFDEAGFPRYVMDEVKAQGFPAPTAIQSQGWPMALSGRDVVGIAETGSGKTLTYCLPAIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQQEITKFGKSSRIRNTCVYGGVPKGPQTRDLSRGVEVCIATPGRLIDMLESGRTNLRRVTYLVLDEADRMLDMGFEPQIRKIIGQIRPDRQTCMWSATWPKEVRALASDFLTDFIQVNIGSMDLAANHRITQVVEVVNESEKRDKMIKHLEKIMEDKESQNKILIFTGTKRVADEITRFLRQDGWPALSIHGDKQQNERDWVLDQFKTGKSPIMVATDVASRGIDVRNITHVLNYDYPNNSEDYIHRIGRTGRAGAKGTAITFFTTDNSKQARDLVGVLQEAKQHIDPRLAEMVRYGGGGGNSRYGGYRGRGGGGFRGGRSQGANGPNAMPMGNRRW",
    "output": "ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHKLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHRDQITALDLAGDELGFPGSLFLSHFNLARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRAGINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK",
    "output": "Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKQPSALSALVEALRVLPGVGPKSAQRMAVHLMQHDREGAERLGRSLLFATEHLQHCEKCNTFTEAQICEVCSDEERDPTLLCVVETPADQIMLEQTMTYRGLYFVLMGRLSPLDGIGPKEIHFDRLVRRASDGVVKEVVLATNFTNEGEATAHYLGQTLKARGLAVTRLARGVPVGGELEYVDAGTIARAMLDRRTM",
    "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTDDMDKVWPTGLTLAEAEEVHKQLIDGTRVFGAIALFAHFLAAIATPWLG",
    "output": "Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGASNNYHHGSNAQGSTAQQDSEETE",
    "output": "RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGYGTRKLSDEYEVSEILGRGGFSVVRKGTKKSSIEEEKSQSQVAIKTLRRLGASNNPSGLPRKKDIGEKSTIGFPTMRQVSVSDTLLTNEILVMRRIVENVSPHPNVIDLYDVYEDTNGVHLVLELCSGGELFDRIVAQDKYSETEAATVVHQIASGLEAVHRANIVHRDLKPENCLFLDVRKDSPLKIMDFGLSSVEEFTDPVVGLFGSIDYVSPEALSQGKITTKSDMWSLGVILYILLSGYPPFIAQNNRQKQQMIMNGNFSFYEKTWKGISQPAKNLISSLLTVDPSKRPSALELLSDPWVKGEKAKDVQMDPEIVSRLQSFNARRKLRAAAIASVWSSTIFLRTKKLKSLVGSYDLKEEEIENLRMHFKKICADRDNATLSEFEEVLKAMNMLSLIPFASRIFDLFDNNRDGTVDMREILCGFSSLKNSKGEDALRLCFQMYDTDRSGCISKEEVASMLRALPYDCLPTDITEPGKLDEIFDLMDANNDGKVTFDEFKAAMQRDSSLQDVVLSSIRP",
    "output": "During nodulation, plays a central role in bacterial infection and contributes to nodule organogenesis . Protein kinase that recognizes the calcium spiking induced by Nod factors and translates this signal to components controlling nodulation and mycorrhizal infection responses. May phosphorylate the NSP1 protein . Required in epidermal and cortical cells to promote infection thread (IT) formation in root hairs ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTGSKMLFACLALIAFLHPLVHVASAQECTTPNNKAGKCLGIRVCKPLLEMLQTQGHAAADFLRQSVCKYENNNPIVCCPNEESREDRGILVGNEYEPLRPPHCGFSNVSHTRVVGGKPAVLGAWPWIAALGFRYPRNPALEPLWKCGGSLISSRHVLTAAHCAEINELYVVRIGDLNLVRNDDGAHPVQIEIESKIIHPDYISGVTKHDIAILKLVEEVPFSEYVYPICLPVEDNLRNNNFERYYPFVAGWGSLAHHGPGSDDLMEVQVPVISNTECKNSYARFAAAHVTDTVLCAGYTQGGKDACQGDSGGPLMLPKKFTFYQIGVVSYGHKCAAAGYPGVYTRVTSYLDDFILPAMQ",
    "output": "Multifunctional venom serine protease. In insects, it acts as an arthropod prophenoloxidase-activating factor, thereby triggering the phenoloxidase cascade. When injected into larvae, it induces a lethal melanization response in target insects by modulating the innate immune response. In mammals, it converts fibrinogen into fibrin, activates prothrombin, and also degrades fibrin. In mammal, it may act in a cooperative manner with the serine protease inhibitor Bi-KTI (AC G3LH89) to promote the spread of bee venom under anti-bleeding conditions."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGQCRSANAEDAQEFSDVERAIETLIKNFHQYSVEGGKETLTPSELRDLVTQQLPHLMPSNCGLEEKIANLGSCNDSKLEFRSFWELIGEAAKSVKLERPVRGH",
    "output": "Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTNYTAINYLLYLLSKRDYSEQDLRRKLVQKEYSQEEIEQAIERAQANNWQSDERYCAGFIRYRSQQGIGPRRLKQELKLKGIKDWLINQELENAEIDWFILAEQVFEKKRPQVWDIKAKQKMWRFMLSRGFYNDHFSHLMDIDYNDTEYE",
    "output": "Modulates RecA activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGSTCSTPESKEQKRINSVIDKQIRKDEDDEIGNQKLLLLGTGECGKSTILKQINILHSSGFSKADLKNVAGTVYSNIIQGVATLLKAKDHFYYELSTPELDADAQHILSLADSSKDAMPFIPLTFNAIKRLWHDPVVQKTFERRAEFQMMDTLVYFMNELDRINNADYIPTVDDMLRIRIPTMGVVQQTIEIKGTKFRIYDVGGQRSERRKWIHLFDNVNATIFISAINEFNQKLNEDGQTNRMKESIKLFETICNSRWFVQAAMILFLNKRDLFEQKLKTTSINVLFSTYQGSNDYAECVAYIQMRFERLNKYSDIKKIYTHVTCATDTNQIQLVIDSVVDMVIGRNLRGTGME",
    "output": "Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDHFLKLLPKLTPQLRKGDCGKIAVIGGSLEYTGAPYYAASSVSRLGADLIHVFCAPDAAPVIKGYSPDLIVHPGMNASSILPKLNRMDAIVVGPGLGRNPTLWPLLQEIFNFVKNEKVPFVIDGDGLWFVSEHIEHFPRQMVTTVLTPNIVEFSRLCKSALGEEDVLNVKSSSQLQHLAAELSRKMDVTIYMKGEVDLVVTPNGEVSKCSTDSSLRRCGGQGDVTAGSLGLFLYWAKKNLGDDWTSAHHEAGISSSWLVRTAGRRAFEKHGRSMNTPLLLDEIPKLVRDVETREMKDTVHSDSSKH",
    "output": "Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRLQRNSIICALVFLVSFVLGDVNIVSPSSKATFSPSGGTVSVPVEWMDNGAYPSLSKISTFTFSLCTGPNNNIDCVAVLASKITPSELTQDDKVYSYTAEFASTLTGNGQYYIQVFAQVDGQGYTIHYTPRFQLTSMGGVTAYTYSATTEPTPQTSIQTTTTNNAQATTIDSRSFTVPYTKQTGTSRFAPMQMQPNTKVTATTWTRKFATSAVTYYSTFGSLPEQATTITPGWSYTISSGVNYATPASMPSDNGGWYKPSKRLSLSARKINMRKV",
    "output": "Involved in cell wall beta(1->6) glucan synthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRLLLTNDDGIMAEGIQVLAKHFEKDNEVIIAAPDVQRSGSGHCITTVPGELIIQEVKLEGINSKAYSITGTPADCARLGVRKLGNNQIDMVISGINNGFNLGIDSLYSGTVSAAIEAAICETPSIAVSLDTKGGNYDYNIAAEYALEVFSIYKDKYKNKDENVVLSLNVPCLPREKIKGLKVCRVGFKYHLQEIYDKGEKTEELSYNYTDIYYVKRGYAALSPLHYDLTNYKILGDINNLFTEK",
    "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAGVEQREGAIQVQGQSLFFREALPGGGQAARFSVLLLHGIRFSSETWQNLGTLHRLAQAGYRAVAIDLPGLGRSKEAKAPAPIGELVPSSFLAAVVDALDLGPPVVISPSLSGMYSLPFLTAPGSQLRGYVPVAPICTDKINAADYARVKASVLIVYGDQDPMGQTSFEHLKQLPNHRVLVMEGAGHPCYLDKPEEWHTGLLDFLQGLA",
    "output": "Acts as an atypical protein-lysine deacetylase in vitro. Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues. Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo. Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate. May activate transcription."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALTADVKDELTKVEVSKTTVRAAELATILRFSGGLHLIGGRIAVESELDTPELARRVRKDLAELYGVRGVVSVISTSGVRRASQYLVRVLDGGETLARQTGLLDAHRRPIRGLPNRLTTGSREELAAVWRGAFLASGSLTDPGRSAALEVTCPGNEAAMALVGAAGRIGVAAKAREVRGVHRVVIRDGEAISAMLVQMGAAQTVSNWEELRQRREVRATANRLVNFDDANLRRSAQAAVAACARVERALEILGDDIPEHLQYAGRLRLAHRDASLDELGHYADPPMTKDAVAGRIRRLLAMADKRASDLGVPSTEASLPADFDEV",
    "output": "Involved in cell division and chromosome segregation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MADDRVAGGATPPPPPPPPPLDASAFTHTPYYCEENVHLLCKELIRSGISDPAGTNLYAVFISNEEKKVPLWYQKASHSGDGFVLWDYHVICIQSRRKNGEVLDLVWDLDSSLPFPCSFIQYVSDAIRPLSFGNSTYRRLFRVIHAPVFLRSFASDRSHMKDHAGNWIQLPPKYESIVAEDGTTNNLNEYITMSMDDVKDLESMADDVYSSKHGVVINETILPEFFSRLPG",
    "output": "Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNLLSLLLILLGIILGVVGGYVVARNLLLQKQSQARQTAEDIVNQAHKEADNIKKEKLLEAKEENQILREQTEAELRERRSELQRQETRLLQKEENLERKSDLLDKKDEILEQKESKIEEKQQQVDAKESSVQTLIMKHEQELERISGLTQEEAINEQLQRVEEELSQDIAVLVKEKEKEAKEKVDKTAKELLATAVQRLAADHTSESTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARTALVNLVSDGRIHPGRIEDMVEKARKEVDYIIREAGEQATFEVNAHNMHPDLVKIVGRLNYRTSYGQNVLKHSIEVAHLASMLAAELGEDETLAKRAGLLHDVGKAIDHEVEGSHVEIGVELAKKYGENETVINAIHSHHGDVEPTSIISILVAAADALSAARPGARKETLENYIRRLERLETLSESYDGVEKAFAIQAGREIRVIVSPEEIDDLKSYRLARDIKNQIEDELQYPGHIKVTVVRETRAVEYAK",
    "output": "Endoribonuclease that initiates mRNA decay."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQNIHFIGIGGIGISALARFLKEKGFKISGSDLKESKITKELEKEGVKVSIPHHKDNILNKDLVIYSAAIKEENPEFKYAKELGIKCLSRKEALPLILEDKRVFAVAGAHGKSTTSSILASLLDDASVIIGAILKEFGSNMIYKESQNLIFEADESDSSFLNSNPYLAIVTNAEAEHLDHYGNEVSKLHHAYAEFLDTAKIRVINAEDEFLKNYKNESIKLYPSKDIKNCTMCIENFKPFTSFELKDLGEFKIFGMGYHLALDASLAILAALNFLDIETIGARLKNYQGIKKRFDILHADENLVLIDDYGHHPTEIKATLSAAQEYAKLGGYKKITAIFEPHRYTRLAVNLKEFAKAFEGVDELVILPVYAAGEEPIEIDLKAVFPKALFVENIQREGKFLVASKGQVFEEGLIIGFGAGDISNKLRQKNE",
    "output": "Cell wall formation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSELKQLVTAPETCGSLMDYLKTFDFIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFAPELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEWANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIKRLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSINTDNRTVSDTNLTKEYELFVKHFETSVSDFLEHNRDAIKASFTSPAEKEALLARLDKAYQSYIKK",
    "output": "Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNVKIDGRRKINSNVIVPPDKSISHRSIMIGSLANGVTEIENFLFSDDCLATINCFKNLSTDIEIRNDKIIVKGNGFALSAPKQILDCQNSGTTTRLLLGILSTQEFESILTGDSSLKKRPMKRVTVPLSQMGAEFEFLEKEDFLPIKVKGSKKLKPIEYTLPIPSAQVKSALIFASLKAEGKSVIKESPKSRDHTELMLKHAGANIKSWEKDGVYTVEILPSQISSIKIKIPSDISSAAFFIVLALICEGSSVVIENCILNPTRTGIIDVLKQMGAEIKIEDVENRNGELVGKIVARSSNLRGVKVEKNDIPRIIDEIPILAVAAAFAEGKTIIDHASELRVKESDRIKTTVEMLKSFGAECYELENGLEIIGSREKLKSAVVNSYKDHRIAMAASIMACAVEGESTILDADCVSISFPNFYDILFSSTKKI",
    "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKVEEILEKALELVIPDEEEVRKGREAEEELRRRLDELGVEYVFVGSYARNTWLKGSLEIDVFLLFPEEFSKEELRERGLEIGKAVLDSYEIRYAEHPYVHGVVKGVEVDVVPCYKLKEPKNIKSAVDRTPFHHKWLEGRIKGKENEVRLLKGFLKANGIYGAEYKVRGFSGYLCELLIVFYGSFLETVKNARRWTRRTVIDVAKGEVRKGEEFFVVDPVDEKRNVAANLSLDNLARFVHLCREFMEAPSLGFFKPKHPLEIEPERLRKIVEERGTAVFAVKFRKPDIVDDNLYPQLERASRKIFEFLERENFMPLRSAFKASEEFCYLLFECQIKEISRVFRRMGPQFEDERNVKKFLSRNRAFRPFIENGRWWAFEMRKFTTPEEGVRSYASTHWHTLGKNVGESIREYFEIISGEKLFKEPVTAELCEMMGVKD",
    "output": "Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNVIEGKMTQDGIKVGIVVARFNEFITSKLLGGAKDGLVRHDVPEENIDVAWVPGAFEIPLIAKKMAKSRKYDAIICLGAVIRGATSHYDYVCNEVSKGIASVSLESEIPVMFGVVTTENIEQAIERAGTKAGNKGYDCALGAIEMINLVRQIG",
    "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTNMWTLLLLPFFAMLQVHYAWCWSPQDRVLLRDIQTITLYADRYTNARRSAPVPQLKCIGGNAGCHAMVPQVVQCHNRGWDGLDVQWECRVDMDNSYRFGKVEVSCEGFDFPEDPYVLRGSCGLEYTLELTEEGRKRTQDGYRSAGFGSGYFQSNSQSWDSKTDGSSAIVLIFIVILAYGVYKLFLSGPSVQQHPRPDEYGYDHQSQTHSSAPPPGFKSDFTGFSSGYGTGHVNQGPGFWTGLGTGGVLGYLFGNRRAQPYQSPYFNTWTGPSHSESMHQNDRPPQSSGVRTASGFGGTKRR",
    "output": "Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (stim1 or stim2)-dependent SOCE activity (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSITLSTLLDLKKKSEKFAVMTAYDATFAYEMDQAGVEVILVGDSLGMVLQGHDSTIPVRLEDMVYHTASVRRGARNAFIIADMPFMSYGTPDQAMAGAKQLMQAGAHMVKLEGGAWLCDAIAHLSRQGVPICAHLGLTPQSVNKFGGYKVQGKEASQAQLMLDDAKALEQAGADILLLECVPTKLAKQLTEEACAPVVGIGAGPYTDGQVLVMHDLLGVGAGKKPKFVKNFLAGSDSIQAAFKGYVEAVKSGAFPAEEHSFNI",
    "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MALAKRIIPCLDVKDGRVVKGVNFIGLRDAGDPVEAAKRYNGEGADELTFLDITASSDNRDTILHIIEEVAGQVFIPLTVGGGVRTVADIRRLLNAGADKVSINTAAVTRPDLIDEAAGFFGSQAIVAAVDAKAANPENTRWEIFTHGGRNPTGLDAVEWAVEMQKRGAGEILLTGMDRDGTKQGFNLPLTRAVAEAVDIPVIASGGVGNVRHLIEGITEGKADAVLAAGIFHFGEIAIREAKRAMREAGIEVRL",
    "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MREIVHIQGGQCGNQIGAKFWEVVSDEHGIDPTGTYHGDSDLQLERINVYFNEATGGRYVPRAILMDLEPGTMDSVRSGPYGQIFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVLDVVRKEAESCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVVPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPTFGDLNHLISAVMSGITCCLRFPGQLNADLRKLAVNLIPFPRLHFFMVGFTPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASALFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNVKSSVCDIPPKGLKMSATFIGNSTAIQEMFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDASAEEEGEFEGEEEEA",
    "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKALANMPGDDYFRHPPVFDTYAEHRAYLKFRHAVALRHFARLGFDQDGLAGLITVADPEHADTYWANPLAHPFSTITPADLIRVDGDSTETVDGQRRVNIAAFNIHAEIHRARPDVQAVIHLHTVYGRAFSAFARKLPPLTQDACPFFEDHEVFDDYTGLVLAKDDGRRIAKQLRGHKAILLKNHGLVTVGETLDAAAWWFTLLDTCCHVQLLADAAGGAEPIPAEVARLTGQQLGSHLLGWNSYQPLHEATLARNPDLAAMAPALPPQTPALAR",
    "output": "Involved in the biosynthesis of ring A of the aminocoumarin antibiotic clorobiocin . Catalyzes two consecutive oxidative decarboxylations of 3-dimethylallyl-4-hydroxyphenylpyruvate (3DMA-4HPP) to yield 3-dimethylallyl-4-hydroxybenzoate (3DMA-4HB) via the 3-dimethylallyl-4-hydroxymandelic acid (3DMA-4HMA) intermediate ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MATTKHLALAILVLLSIGMTTSARTLLGYGPGGGGGGGGGGEGGGGGYGGSGYGSGSGYGEGGGSGGAAGGGYGRGGGGGGGGGEGGGSGSGYGSGQGSGYGAGVGGAGGYGSGGGGGGGQGGGAGGYGQGSGYGSGYGSGAGGAHGGGYGSGGGGGGGGGQGGGSGSGSGSGYGSGSGGGNGHH",
    "output": "Responsible for plasticity of the cell wall."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAPNLQPQPQSQLQRPRLKDHRPWSGLSNISKRSFRSCATSAFEADDERSSSDGDMSPRNSEADLRRPVVPRHFGHDARPTSRRELLGWYAYAFAAETYVICGIASFIPILLETLARENGVLVSDRKTPCGSSDSKNDGDGQCIVWVFGMEINTASFAMYTFSVSVLVQALLVVSISCAADHGNYRKKLLLTFAWIGSFAVMSYIFITKDNYILGALLTVISNTSFGASFVLLNSFLPLLVRYHPDVIEANVATTPDLGSSEFESRPLDQSVGQLESSPVTATSPLLHPEDGGRLKPTASHAEITSKELELSTRISAIGIGTGYIAALFLQCICIGVLISLHNTTWGQRVVLFMVGVWWTVFTIPAAMWLRPRPGPPLADNGRKGIMAGLAYILYAWKSLFKTIQQARRLLDIVLFLAGWFLLSDAIATTSSTAILFAKTQLHMKPWALGMINVISTTAGVFGAFGWSWVSRLFNLKAHQTILVCIALFELIPLYGLLGYLPFVKNWGVFGLQQPWEMYPLAAVYGVVLGGLSGYCRSLYGELIPPGSEAAFYALYAITDKGSSVFGPTIVGAIIDRTGTIRPAFWFLAVLVGFPAPLIWFIDVERGRREGAKLAKSITDSIVQEEDESDDGAERRGMLSDYEREHGQSIDDERAGR",
    "output": "Vacuolar effluxer which mediate the efflux of leucine and other amino acids resulting from autophagic degradation (By similarity). The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity). Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence . Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKNINPTQTSAWQALQKHYDEMKDVTIAELFAKDSDRFAKFSATFDDLMLVDFSKNRITEETLAKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHVALRNRSNTPIIVDDKDVMPEVNAVLEKMKTFSEAIISGQWKGYTGKAITDVVNIGIGGSDLGPFMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKTAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIILSVGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNAVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPAQLEHVVPFKVFEGNRPTNSILLREITPYSLGALIALYEHKIFTQGAILNIFTFDQWGVELGKQLANRILPELGDDKAISSHDSSTNGLINRYKAWRA",
    "output": "Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFKFGKKLMTVVLAASMSFGVFAATTGATDYWQNWTDGGGTVNAVNGSGGNYSVNWQNTGNFVVGKGWTYGTPNRVVNYNAGVFSPSGNGYLTFYGWTRNALIEYYVVDNWGTYRPTGTYKGTVNSDGGTYDIYTTMRYNQPSIDGYSTFPQYWSVRQSKRPIGVNSQITFQNHVNAWASKGMNLGSSWSYQVLATEGYQSSGSSNVTVW",
    "output": "Involved in depolymerization of xylan, a major component of the lignocellulosic substrates. Acts as an endo-xylanase that efficiently hydrolyzes the beta-1,4 glycosidic linkages between the xylopyranosyl residues in the main chain of the polymer, leading to the degradation of xylan into short oligosaccharides. Shows high activity toward branched xylans from both softwoods (arabinoxylans) and hardwoods (glucuronoxylans), showing the highest activity on beechwood xylan. Also hydrolyzes long xylooligosaccharides (with a degree of polymerization of greater than or equal to 5), while oligomers shorter than xylotetraose are not degraded. Is not active on carboxymethyl cellulose (CMC), Avicel, starch, polygalacturonic acid, laminarin, pectin, beta-D-barley glucan, or lichenan."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGLQGPAKVAIIGTGYVGSSTAFALLFSPLVKEMVLVDVNHAKAEGEAMDLAHAATLIRPVEVYAGRPADCAGSRIVIFTAGANQQPGQTRLDLIHRNTAIVRQALPEILHYCPEALVLMVANPVDILTYVAWKISGLPENRVLGSGTVLDSARFRHLLSRHYRVDPRNIHAYVIGEHGDTEVPVWSLANVAGVDLEEFYLMDGMREEEAFRVEISHQVREAAYEIIERKGVTSYGVALALSRIIECILRNEHSVLTISSVIRDLYGIDGEVALSLPCLVGNEGREKVLAIPLVAREKAALKHSATTLQQLIAQLSL",
    "output": "Catalyzes the conversion of lactate to pyruvate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQLNDLRSAPGARREKHRPGRGIGSGLGKTGGRGHKGLTSRSGGKVAPGFEGGQQPLHRRLPKFGFVSLKAMDRAEVRTSELAKVEGDVVSLQTLKDANLINQHVQRVKVMLSGEVGRAVTLKGIAATKGARAAIEAAGGKFED",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSNECFKCGRTGHWARECPTGIGRGRGMRSRGRAGFQFMSSSLPDICYRCGESGHLAKDCDLQEDKACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA",
    "output": "Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (By similarity). Has a role as transactivator of the Myc promoter (By similarity). Binds single-stranded RNA in a sequence-specific manner (By similarity). Binds G-rich elements in target mRNA coding sequences (By similarity). Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIKSKFIVIEGLEGAGKTNACICIKNLLKKNSIKNVLLVRQPGSTPIAEDIRRLIKKKFNDDNLIKETELLLMYAARIQLVEKKIKPALKNGIWVISDRHDLSSLAYQGGGLGIPKKIIYQLQSLFLNNFIPDLTIYLDVSPEIGLARALKRNPLDLIESRSLFFFKKTRRCYLEKSKLDKKTIIINANLNIKKVTQNITKKMLNWLNKQVI",
    "output": "Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDFALPTTASQASAFMNNSSLTFPVLPNANNEATNETADSGDAEVSKNEGVSGIVPTLQNIVATVNLDCRLDLKTIALHARNAEYNPKRFAAVIMRIREPKSTALIFASGKMVVLGGKSEDDSKLASRKYARIIQKLGFNAKFTDFKIQNIVGSCDVKFPIRLEGLAYSHGTFSSYEPELFPGLIYRMVKPKVVLLIFVSGKIVLTGAKVREEIYQAFEAIYPVLSEFRKH",
    "output": "General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGEALDEIQWKSPEFIQERGLHTGNVLEYFSLSPFYDRTSNNQQLMMQFQFQQIQIPVNTTFQQFFQEKLREMTGVVFVIAYNREPDFWIIRKQLQLDPQNAVTLQDYYIIGANVYQAPKVYDVLSSRLLSSVLQLRNSIDLLNKMTQFHVSDGGHSYNNAIHQSTSNPTQGQSSGKSISATVGNTGTTATPMTMQTPQTVGPNGPATVQSGANSAAAISKNGSTSSAESADDRKNIYLDDIPLYGRGSTVEMLGLKVNLES",
    "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIKKRQTRIAMIAGEMSGDLLGAGVIRELKKHLKNVEFIGVGGPQMLEEGFQSLANMSELSVMGISDVLRRYPQLYFIRERLLKEWTINPPDVFIGIDYPDFNLSVETRLKRQNVKTVHLVSPKVWAWRQKRVYLIKKAVDLVLTLFPFEESFYQQYDVPAQFVGHPLADLIEINPNNADLRKKYNYKPDDTILAVLPGSRIGEIKYIGPLFLEVMQRIAVEMPHVHFIVPIACQELYPVFFKQFQARYSHLKIQIIQGNAREAMAISDVVLTKSGTATLEAMLLKRPMVVAFKWSKFTHAIIAPQVKIPYVALPNLLANKKLVPEFVQEKATANSITESVLNLLACPSQSNLNKQFTAIHHTLRQNANEKAALSILKILETSSA",
    "output": "Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAKGGTVKAASGFNAAEDAQTLRKAMKGLGTDEDAIINVLAYRSTAQRQEIRTAYKTTIGRDLMDDLKSELSGNFEQVILGMMTPTVLYDVQELRKAMKGAGTDEGCLIEILASRTPEEIRRINQTYQLQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDESNYLDDALMRQDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRIAQKDIEQSIKSETSGSFEDALLAIVKCMRNKSAYFAERLYKSMKGLGTDDDTLIRVMVSRAEIDMLDIRANFKRLYGKSLYSFIKGDTSGDYRKVLLILCGGDD",
    "output": "May play a role in alveolar type II cells through interaction with the surfactant protein SFTPA1 (SP-A)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MERRSALPQDFREVLHCLKMRSKYAVLLVFVVGLVIIEKENNFISRVSDKLKQSPQVLPEANETEASPVQAENGSLASLRQLDTAFSQLRTRLRNVTLQLAGELGIAAPEPRRHVLLMATTRTGSSFVGEFFNQQGNIFYLFEPLWHIERTVTFEPGGANAVGSALVYRDVLQQLLLCDLYILESFISPAPEEHLTAALFRRGSSHSLCEEPVCTPSLKKVFEKYHCKNRRCGPLNITLAAEACRRKQHMALKTVRIRQLEFLQPLAEDPRLDLRIIQLVRDPRAVLVSRMVAFSGKYESWKKWAAEGEAPLQEDEVQRLRGNCESIRLSAELGLRQPRWLRGRYMLVRYEDVARAPLRKALEMYRFAGIHPTPQVEEWIRANTQAPQDSNGIYSTQKNSSEQFEKWRFSIPFKLAQVVQDACEPAMRLFGYKLASSAQELTNRSLSLLEEGPPTRIT",
    "output": "Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin . Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices . Catalyzes with a lower efficiency the sulfation of Gal residues of keratan sulfate, another glycosaminoglycan . Can also catalyze the sulfation of the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTLNKTDRIVITLGKQIVHGKYVPGSPLPAEAELCEEFATSRNIIREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTDVLQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNPVLQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMIASSTRRLKEIT",
    "output": "Involved in the regulation of D-galactonate metabolism . Represses the expression of the dgoRKADT operon by binding to two closely spaced inverted repeats in the cis-acting element, which overlap with the D-galactonate responsive dgo promoter . Employs a derepression mechanism using D-galactonate as a specific effector molecule ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MENKHIPILLNEAIKSLNIKSDGIYLDLTVGMGGHSSEILKRLKNGLLVGFDKDLFAIEESRKRLSKIGSNFQLIHSDFNNVADELAKLNINAVDGILVDLGISSPQVDNAERGFSYSKDARLDMRMNTNQALDAHFVVNTYSEDELITIFYNYAEVKLAKQVANAIIKNRPINTTLELAEVIKSAYPAKLLSLKNPCKAVFQAIRIEVNNEFSSINSMLVQALNLLKKDSSLAIITFHSLEDSIIKKFFGNLIKSKHPSKMPIKEEKKYIVKVYSPSKAEISENNRSRSAKLRVLTKLI",
    "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATTTLPNTKQQAAQFANSVADRAKENIDAAKEQLQKALDKLGKTGKKLTLYIPKNYKKGNGLTALIKAAQKLGIEVYHEGKDGPALTNGILNTGKKLLGLTERGLTLFAPELDKWIQGNKHLSNSVGSTGNLTKAIDKVQSVLGTLQAFLNTAFSGMDLDALIKARQNGKNVTDVQLAKASLNLINELIGTISSITNNVDTFSKQLNKLGEALGQVKHFGSFGDKLKNLPKLGNLGKGLGALSGVLSAISAALLLANKDADTATKAAAAAELTNKVLGNIGKAITQYLIAQRAAAGLSTTGPVAGLIASVVSLAISPLSFLGIAKQFDRARMLEEYSKRFKKFGYNGDSLLGQFYKNTGIADAAITTINTVLSAIAAGVGAASAGSLVGAPIGLLVSAITSLISGILDASKQAVFEHIANQLADKIKAWENKYGKNYFENGYDARHSAFLEDSLKLFNELREKYKTENILSITQQGWDQRIGELAGITRNGDRIQSGKAYVDYLKKGEELAKHSDKFTKQILDPIKGNIDLSGIKGSTTLTFLNPLLTAGKEERKTRQSGKYEFITELKVKGRTDWKVKGVPNSNGVYDFSNLIQHAVTRDNKVLEARLIANLGAKDDYVFVGSGSTIVNAGDGYDVVDYSKGRTGALTIDGRNATKAGQYKVERDLSGTQVLQETVSKQETKRGKVTDLLEYRNYKLDYYYTNKGFKAHDELNSVEEIIGSTLRDKFYGSKFNDVFHGHDGDDLIYGYDGDDRLYGDNGNDEIHGGQGNDKLYGGAGNDRLFGEYGNNYLDGGEGDDHLEGGNGSDILRGGSGNDKLFGNQGDDLLDGGEGDDQLAGGEGNDIYVYRKEYGHHTITEHSGDKDKLSLANINLKDVSFERNGNDLLLKTNNRTAVTFKGWFSKPNSSAGLDEYQRKLLEYAPEKDRARLKRQFELQRGKVDKSLNNKVEEIIGKDGERITSQDIDNLFDKSGNKKTISPQELAGLIKNKGKSSSLMSSSRSSSMLTQKSGLSNDISRIISATSGFGSSGKALSASPLQTNNNFNSYANSLATTA",
    "output": "Virulence factor that plays an important role in immune evasion. Lyses human lymphocytes and monocytes. Binds to the LFA-1 integrin on the surface of the host cell and to cholesterol-containing membranes, which probably results in large LtxA-LFA-1 clusters in lipid rafts. Shows also beta-hemolytic activity on certain types of growth media."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "RRLSLHEYLSMGLLQEAGISVPHGVVARTPDEAYKIAKEIGSKDLVIKAQVLAGGRGKGTFEGGLKGGVKIVFSPEEAKAVSSRMIGKKLFTKQTGEKGRICNQVFVCERRYPRREYYFAITMERSFQGPVLIGSSQGGVNIEDVAAENPDAIIKEPIDIVEGIKKEQAVRLAQKMGFPSNLVDEAAENMIKLYNLFLKYDATMIEINPMVEDASGVVMCMDAKINFDSNSAYRQKKIFDMQDWTQEDERDRQAAKADLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVVAVKDLDLKIPVVVRLQGTRVDDAKALITASGLKILACDDLDEAAKMVVKLSEIVTLAKQAHLDVKFQLPI",
    "output": "ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSGRIVQIIGAVIDVEFPRDQVPNVYEALKVQGAETTLEVQQQLGDGVVRTIAMGSTEGLKRGLDVNSTGKAISVPVGKATLGRIMDVLGNPIDEAGPIGEEEQWEIHRAAPSYAEQAGGNDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKKGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPNVIGQEHYETARGVQYVLQRYKELKDIIAILGMDELSEDDKLLVARARKIQRFLSQPFFVAEVFTGAPGKYVSLKDTIAGFSGILKGDYDHLPEQAFYMVGGIDEAIEKAKKL",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKKGTVLNSEISSVISRLGHTDTLVVCDAGLPVPHSTTRIDMALTQGVPSFMQVLDVVTAEMQVETAILATEIKQHNPQLHETLLGHIEQLQQHQGNTIEIRYTTHEQFKQQTADSQAVIRSGECSPYANIILCAGVTF",
    "output": "Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIGLENELTAEDVASADMVILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMSKIEAHLAQTA",
    "output": "The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FrwABC PTS system is involved in fructose transport."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSVLNTFLVIVALILCYVNDFPVTGHEVQLPPGTKFFCQECQMTAVIHVLKHRGCKPKAIPSFACIGKCTSYVQVSGSKIWQMERTCNCCQESGEREATVVLFCPDAQNEEKRFRKVSTKAPLQCMCRPCGSIEESSIIPQEVAGYSEEGPLYNHFRKSL",
    "output": "Final heterodimeric neurohormone released at the end of the molting cycle, involved in the sclerotization (tanning) of the insect cuticle, melanization and wing spreading."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDFGIGFLSNNVMLPILDFFYGIVPSYGLAIVALTLVVRFAVYPLSAGSIRNMRRMKVVQPIMQKRMQEIQQKYKDNPAEQQKAMAEVYREFGNPLAGCFPLLLQLPILFALFATLRGSPFADVNYQINLQIVPPDQPVLAQPFATKPQNIYVDEGVHFPIQAVVPSGTRIPVGQMVDLQFQTKEGKPFSELVAAYPNSHLQPKWQIIRGQERATIDREGHLQALQPGEVTVQGTIPGIAADKGFLFISALGHVGVIDQGELFITLPDGARQFNWGAIHWDILVMILGFGVSLYVNQLLSGQGSSNNPQQQTVNQLTPIIFSGMFLFFPLPAGVLLYMLIANIFQTVQTFILQREPLPENLQKLVEEQERAEAIKNRAPLPFEGKGAKGAKATKAKGNPSS",
    "output": "Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity).; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFLPKAAVSAFSMHGSLCFLWTVCLSISPLSQQGVQAFQCSNGVSLPSDYVCDFTDHCGDNSEEQQCWSYGRCNFEDRLCSMTEDQTLQPGWTRRSGIISNSPPFWDHNGNISAHFLALVSRVDSISSNLRSRIFLPTNDQQVCQITFYNFSSNQNGKLIAGLQTLCGDPIEHLWQKTEILQSRWERNVITVQSSQQFQVIFQAQMLATHGQEEVIAIDDISFSSGCLPADVCQTCGFDLDTCGLATEASAGRTSWMCTKVREIPSLDSVPWQDQRGHDEGSFVWMRAGHASVSRLVESSAYLNSSVCHCMDGNCRLQFNYTMENSILRVRLYNDKEEKKTWTFNTSTYSTWMKADVLIPEDLKAFKVVLEGTVLSQKSFIGIDQLLVYNFGQTHSQKLCSVNEYTPASRQCLTHSSVCDSGMDHSNGIDEDSEACASLLTWDFESGFCGWEPFPTEDSHWEVVRGLSNGEHLFLEAGHTVSRNQGSFIYFGPQKSTAVARLGSPILTKSLTTFTPCQVRFWYHLSEHSSLSVFTRTSVDGSLLKQSEVTQFSDSQWSQAKVDLHAKAEESTLPFQLVLEATILSSNATVAVDDISISHECEISYKSLRSTSIQNKVADCDFEANSCGWFEASGGDHFDWVWSSQSNLSADLEQQAPPRDHTHGTAQGHFMFILKTSNSLFQTAKLQSPTFSQTGPGCTMSFWFYNYGLSVGAAELQLHLENSRDTTALWRVLYNQGNQWSEATVQLGRLTQPFYLSLEKVSLAVYSGVSAVDDIHFENCALPPPVESCDEPDHFWCRQTKACIGRHQLCDLVDDCGDYTDETGCAPGLQCNFENGICNWEQSTKDDFNWTRYQGPTSTMNTGPMKDHTLGTAKGHYLYIETSGPQGFQDKAVLLSPILNATEAKVCTFRLYYHMFGKHIYRLAIYQRIWSNTKGQLLWQIFGDQGNRWIRKDLSITSRKPFQILIMASVGDGFTGDIAIDDLSFMDCTLYPDNLPMDIPSPPETSVPVTLPPNNCTDDQFVCRSNGHCVGNIQKCDFRYDCIDKSDESSCVLEVCTFEERKLCKWYQPIPANSLHDSNTFRWGLGNGISIHHGEENHRPSVDHTKNTTDGWYLYADSSNGKFGDLADIVTPVISLMGPRCTLVFWTYMNGATVGSLQVLIKMGNTISKVWAQSGQQGPQWKKAEVFLGIHSHVEIVFRAKRGVSYIGDVAVDDVSFQNCSPLLSTNRKCTTDEFMCANKHCIEKDKLCDFVNDCADNSDETTFICGTSSGRCDFEFDLCTWEQDQDEDIDWNLKASNIPATSTEPAVDHTLGNSSGHYIILKSFFPQQPVKTGRISSPVISKRSKDCKIIFNYHMYGSGIAALLLLQVTVTNHTRVLLNLTKEQGNFWQRKELSLSSDEDFRVKFEGRVGEGIRGNIALDDIVLTKSCLPSHHSTREEPAFPLPTGFCPRGYEECQNGRCYSPEQRCNFVDDCGDNSDENECGGSCTFEKGWCGWKNSLAENSDWVLGIGSYKSQRPPKDHTLGNEHGHFMYLEATPVGLHGDKAHFKSATWQESSAACTMSFWYFISAKATGSIQILIKTDKGLWEVWQQSKPDPGNHWRRATILLGKLRNFEVIFQGIRTRDLGGGAAIDDIEFNNCTTVGETTDICSEETDFLCQDKKCIASHLVCDYKPDCSDTSDEAHCGYYTSTAGSCNFETTSGDWTVECGLTQDPEDDLDWSIGSIIPTEGLSRDSDHTPGSGRHFLYVNTSLAEEGSTARIITSHFFPASLGICTVRFWFYMVDPHIVGILKVYLIEKSGLNILMWSMMRNKNTGWTYAHVPLSSNSPFKVAFEADLGGKEDIFIALDDITFTPTCASGGPALPQPPLCEEGQFACIYALQCVSASEKCDGQEDCIDGSDEMNCSLGPSPQPCSDTEFQCFESQCIPSLLLCDGVADCQFNEDESSCVNQSCPSGALACNSSGLCIPAHQRCDGTAHCKDIQVDESSCSECPIHYCRNGGTCVIENIGPTCRCVQGWTGNRCHIRSNLSTEGSVHTQNYIWTLLGIGLGFLLTHIAVAILCSLGIRRRPMRKSEGVGNHSFINPVYRNCINQEKTQSSIYSFPNPFYGAASGSLETVSHHLKS",
    "output": "Enhances production and/or transport of FGF15 and thus has a role in regulation of bile acid synthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MELDDILDAGRGDRLFLLGNEAAVRAAIESGVGVASTYPGTPSSEIGNVLSKIAKRAGIYFEFSINEKVALEVAAAAAASGVRSFTFMKHVGLNVASDSFMSVAYTGVRAGMVVLSADDPSMFSSQNEQDNRHYARLAWVPLLEPSNPQEILEYMNHAFELSEEYRIPVLLRTTTRVSHMRGVVEAGERRAEPVKGFFRKNPEQFVPVPATARVMRRELVEKMKKLKRVADTSELNRVLNEDSESDLGIIASGGAFNYVYDALQTLGLDVPVLKLGFTYPFPAGLVAEFLSGLEGVLVVEEVDSVMEKEVLAVATSEGLDVGVHGKLDGTLPEIYEYSEDIVRRAISGLTGIKSHEKGIEAPELPERPPALCPGCPHRAMYYSVRRAASELGIEGEDLIFPTDIGCYTLGIEPPYSAADYLLSMGSSVGTACGFSAATSQRIVSFIGDSTFFHAGIPPLINAVHNRQRFVLVILDNRTTAMTGGQPHPGLPVDGMGEEAPAISIEDITRACGVEFVETVNPMNIRRSSETIRRALQHESVAVVISRYPCMLSEGAVRGRPVRVDEEKCDLCLECLNELACPAIVEEDGRVFIDPLYCRGCTICLQICPAGAIKPEGKR",
    "output": "Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MASGTTIQPSRPSLTSNDSAVLQALFDAESSPSSAVAIDPSLSPFPEYLHISASDHESLKARELSIIRSLQSDDVSMDTITSAIRDLDALITEHPTYPSAYVNRAQALRLHIEKTAEASTDPEEAIFTPGNTESASRLFSDLGQAISLCTPRSPADPVSTVQARILADSHTHRGYLLLKAARLKKNANGNEMVGGPDKLRDMGPDQLEEMASRDFFFGGRYGNKVAQQLAVQTNPYAKMCGAIVKEALRKEVEGVI",
    "output": "Part of the L-tyrosine degradation gene cluster that mediates the biosynthesis of the brownish pigment pyomelanin as an alternative melanin . The 4-hydroxyphenylpyruvate dioxygenase hppD catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisic acid (HGA) . The protein hmgX is crucial for this conversion and thus, probably functions as an accessory factor to mediate specific activity of hppD . The homogentisate 1,2-dioxygenase hmgA is then involved in the cleavage of the aromatic ring of HGA and its conversion to 4-maleylacetoacetate . When hmgA activity is lowered by the cell wall integrity (CWI) signaling pathway, HGA accumulates and leads to the production of pyomelanin through benzoquinone acetic acid after oxidation and polymerization . On the opposite, in non-stress conditions, both hppD and hmgA activities are balanced and HGA is degraded into 4-maleylacetoacetate . 4-maleylacetoacetate is further converted to 4-fumarylacetoacetate by the maleylacetoacetate isomerase maiA, which is degraded into fumarate and acetoacetate by the fumarylacetoacetase fahA (Probable)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTRIKRGYIARRRRTKLRLFASSFRGAHSRLTRTMTQQRIRALVSAHRDRGKRKRDFRRLWITRINAVIHEMGVFYSYNEFIHNLYKKQLLLNRKILAQIALLNRSCLYTISNDIKK",
    "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIKVEIKPSQAQFTTRSGVSRQGKPYSLNEQLCYVDLGNEYPVLVKITLDEGQPAYAPGLYTVHLSSFKVGQFGSLMIDRLRLVPAK",
    "output": "Binds to DNA in a highly cooperative manner without pronounced sequence specificity. During synthesis of the single-stranded (progeny) viral DNA, prevents the conversion into the double-stranded replicative form. G5P is displaced by the capsid protein G8P during phage assembly on the inner bacterial membrane."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSRAIAADKREDDSQFDSTLRPKSLDDYIGQEKIKGNLRLFIEAARGRGEALDHVLLYGPPGLGKTTLANIVACEMGVNLKSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARSIKLDLPRFTLVGATTRAGLLSSPLRDRFGVISRMDFYTHDELATIITRSSRILGMEIEPRGADELSRRSRGTPRIANRLLRRVRDFAQVRADGVITRQVVKETLALLEIDEMGFDHMDRMILLTIIDKFSGGPVGLDTIAAAISEESDTIEDVYEPYMIQNGFLNRTPRGRVATLAAYEHFGRSVPAAPQAALL",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKVLGLDVGDKKIGVALSDELGLTAQGLTVIYRTSLKKDLEEIKKIIDLHHVTEVVIGYPRNMNGTAGPRAELVKRFARELYKFTGIKPVFWDERLSTVEAEKLLISGDISRRKRKKVIDKLAATLILSGYLNYKSKN",
    "output": "Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRIKLNTEDIMRISLFEKMTGANVIDSTSDDEKIVFVVKEGDIGAAIGKGGENVKNATDKFGKKIDLIEYSEDLKQFIKNIFAPIELEDVWVKKFGNDLVVYVRVHPRLRRAIIGDKGKNIDRAVDIAGRLAGVKNIKVVAGLRKDADNRPKKDEIPEKAAESSENVQAEENQ",
    "output": "Participates in transcription termination."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSFINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMIEEYLTTRQNLRAVVSLVDFRHEPSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNKHESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL",
    "output": "Necessary for normal cell division and for the maintenance of normal septation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MATLFIADLHLCAEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF",
    "output": "Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTAEDAAAAMSSDSAAGGAASAKAPEGVAGAPNEAALLALLARTGYRMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVTYCHKGEAKRAVRELNNHEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFASREDAVLAMNSLNGTELEGSCLEVTLAKPVDKEQYSRYQKAAKGGGAAEAAAPQPGYVYSCDPYTLAYYGYPYNALIGPNRDYFVKAGSIRGRGRGAAGSRAPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEISAVNPVAIKPGTVAIPAIGAQYSMFQAAPAPKMIEDGKIHTMEHMISPIAVQPDPASAAAAAAAAAAAVIPAVSTPPPFQGRPITPVYTVAPNVQRIPAAGLYGAGYVPFAAPATATLATLQKNAAAAAVYGGYAGYIPQAFPAATIQVPIHDVYPTY",
    "output": "Single-stranded RNA-binding protein that functions in a variety of RNA processes, including alternative splicing, RNA stabilization, and RNA editing. Functions as an enzyme-substrate adapter for the cytidine deaminase APOBEC1. With APOBEC1 forms an mRNA editing complex involved into cytidine to uridine editing of a variety of mRNA molecules. Through the binding of their 3'UTR, also stabilizes a variety of mRNAs and regulates the expression of genes such as the interferon alpha/beta receptor and interleukin-10. Also involved in the alternative splicing of several genes including TJP1. Binds the pre-mRNA (U)GCAUG consensus sequences in downstream intronic regions of alternative exons, regulating their exclusion and inclusion into mRNAs (By similarity). Independently of its RNA-binding activity, could negatively regulate MAVS by promoting its lysosomal degradation (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSEKAILSCRNLGKSYEEGPESVEVLANLQLELHPGERVAIVGKSGSGKSTLLNLLGGLDTPTKGGVWLDGEELSALSEKKRGLLRNRALGFVYQFHHLLPEFTALENVCMPLLIGKTAIPEARQRATALLERVGLGHRLEHKPAELSGGERQRVAIARALVNNPGLVMLDEPTGNLDSHTAEGIQDLMLELSTSMRTAFLVVTHDMNLARQMDRVLQLQEGCLTPI",
    "output": "Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSALCPLLTPPASEALLLAQARQLSGYTLGELAAMAGITTPKDLKRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRVLWVPVEGDRSIPLAERRVGSPLLWSPSEEEDRQLRLDWEELMDMIVLGQVERITARHGEVLQLRPKAANARALTEAIGARGEPILTLPRGFYLKKNFTQALLARHFLLQNP",
    "output": "Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRILKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQLETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIESLITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGSPPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVSGSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGEALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEECFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGASAKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYKAKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTAETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMDSPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLYQAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKEDFYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQLFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDVLLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDALLTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVIENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGILKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKPPTSWGLTAYSEKHHWHLCCDSSRTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIGGLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKDDKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVIEELNVVLQRSRTLPKELQDEQILK",
    "output": "Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQALVNRLWYDRQAGVHWLLVLLLLPLSGLFYLLTSLRRQLFRLGLKASARLDVPVIVVGNITVGGSGKTPTVIYLIELLRRNGYRPGVISRGYGVEFSGCKRVIAGMPANEVGDEPAMIVARTQVPMVIGSDRVAAGKALMDWQAVDVIISDDGLQHYRLKRDIEILVLDGKRRFGNGLLLPAGPLREGRWRQGRVDFTLVNGEGSGPEEFEMALAPGNWRSVADGQVVTANVDKSHESVAIAGIGNPQRFFDTLSEIGVQPSGQHAFDDHQAYSLEAIETVAAGRGVLMTEKDAVKCREFAKSNWWYLPVDAKIAPEFEQQLLTLLKRRENVQQGN",
    "output": "Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIIVTGGAGMIGSNIVKSLNDKGFNDILVVDNLKDGKKFKNLVDLDITDYMDKEDFITQIMAGDDFGPIEAIFHEGACSATTEWDGKYIMMNNYEYSKELLHFCIEREIPFLYASSAATYGETDTFIEEREYEGALNVYGYSKQQFDNYVRRLWADAEEHNETLSQITGFRYFNVYGPREQHKGSMASVAFHLNNQMNAGDNPKLFEGSDEFKRDFVYVGDVAAVNLWFLENGVSGIYNCGTGRAEPFRAVAEAVIKHHGKGEVETIPFPEHLKGAYQEFTQADLTKLRAAGCDVEFKSVADGVAEYMAMINK",
    "output": "Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRVLFAGTPAVAVPSLDALVQAGFDVVAVLTRPDAPVGRKRVLTPSPVAARAAELGIEVIHAAKVDAEVTARIAAAAPDAAAIVAYGGLIPRAALDVPRHGWINLHFSLLPAWRGAAPVQRAVMAGDDITGAVTFLLEEGLDTGPVFGTLTESVRPDDTSGELLERLSHSGAALLAQTLSAIEAGRAVAVPQSGDVSLAPKLGIDDGRIDWHEPALAIGRRARGVTPEPGAWTTLDGQRVKLEPVALRTDAPALQPGQVLLDGKSVLVGTGSHPVELTRIQPSGKKMMAAADWARGQVALEGVVFE",
    "output": "Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQKTISHAFPLGDVTWSNQGRLSIPNAHLESWLLNTGSLTQRLQTRCNDFKVQLVSQRQELATPAEYIQLGVSKMSQQKENWQVREVILHGDNQPWVFARSIIPQALCEADFLELGDKPLGHLIFNDDRFKRQPFQLMCLQPDEAFLHEYGLPPLTEIWGRRSVFCYQQYAMMVAELFLPKAPAYRDSNFDR",
    "output": "Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAGGFVSQTPGVRNYNYKLTPKVFVTCFIGAFGGLIFGYDLGISGGVTSMEPFLEEFFPYVYKKMKSAHENEYCRFDSQLLTLFTSSLYVAALVSSLFASTITRVFGRKWSMFLGGFTFFIGSAFNGFAQNIAMLLIGRILLGFGVGFANQSVPVYLSEMAPPNLRGAFNNGFQVAIIFGIVVATIINYFTAQMKGNIGWRISLGLACVPAVMIMIGALILPDTPNSLIERGYTEEAKEMLQSIRGTNEVDEEFQDLIDASEESKQVKHPWKNIMLPRYRPQLIMTCFIPFFQQLTGINVITFYAPVLFQTLGFGSKASLLSAMVTGIIELLCTFVSVFTVDRFGRRILFLQGGIQMLVSQIAIGAMIGVKFGVAGTGNIGKSDANLIVALICIYVAGFAWSWGPLGWLVPSEISPLEIRSAAQAINVSVNMFFTFLVAQLFLTMLCHMKFGLFFFFAFFVVIMTIFIYLMLPETKNVPIEEMNRVWKAHWFWGKFIPDEAVNMGAAEMQQKSV",
    "output": "Mediates an active uptake of hexoses, probably by sugar/hydrogen symport. Can transport glucose, methylglucose, galactose, xylose and mannose, but not fructose."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MMKTHNLFVSCIESRVQDQGSLYARFHIGTFFRGQALTFGNSIRRALLSEMPGFLMTDVRIQGATHEFAVLPDVEETVLEILLNLKKTVFVPRIPKNQKFETFQGFGFLKNNGPGKVRAADIRLPETVQCVSPEVHIATLTSGAELSLRFNLQFRNFSQLEKREGTFKSKTVAQAKTEDGNVQDTTNELPTLEKNSLFFQQLQNKRNSKDQLFLDTVPMPVQKVNYVIKSLNAKNGSEYIILEIWTDGSLYPQESVEFALRNLTDLFFQFANISKKSN",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREKGMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAEGKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKADEQHFGAYQHNGGRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNESRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFESEVAATMAAALNN",
    "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATDGMVLHKRSLSEGGTSTQAWKVLSQTLPSRGPDVDAWWQLTGRHLAVLLDAAAYPIEKQYECLLYHYHYAAPYLGPAPREGASPPTWKSMLQLDGTPFEFSWKWNNPGGEPDVRFGLEPIGPMAGTSLDPLNHLAMREILYKLSSAVPGSDLTWTHHFLATLFDHDYAKYTQKAATMGSSIGTSLVYSLEFQRKSTGLKTYFHPRKLDQQAFLDIPSWEASFRGLHPNSPSRTAVHEFLSTNPEGKLLKPFCLSVDNCSPAKARIKWYFNSPHTNFRAIREIMTLGGRIADTETRTKQFSELFNLLKTVTEEHADFPETSEFPYVPNNGDSIIPNFADAPDMLKGCVYFFDIAPGRNLPAIKVYFPVRNHCRNDLAVTQNLNRWLESRGRGQYGAAFGRALETIADYRRLEDSGGLLSFLSCQFMEDGELDLTSYFNPQAFHSGRLTHRRATRRRGDDRW",
    "output": "Dehydrogenase involved in the conversion of monodictyphenone to the prenyl xanthones such as emericellin, shamixanthone and epishamixanthone . Monodictyphenone is first converted to variecoxanthone A via a paeciloxanthone intermediate by the consecutive actions of the FAD-dependent monooxygenase mdpD and the xanthone prenyltransferase xptB . XptB catalyzes regular O-prenylation at the hydroxy group of C-7 of the xanthone ring . Variecoxanthone A is further prenylated to emericellin by xptA before being reduced to shamixanthone and epishamixanthone by the dehydrogenase xptC ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAVADIKTAKIVKENARSANDTGSPEVQVSLLTARINELTPHFKANTKDHHSRCGLLKMVSRRRRLLDYLKGKDLDCYRALIEKLGLRK",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDGMIAMLPAPLQKLSSHIDFQGQKVAERTYQVILTIAGIIGFLVGFWTQQLSYAMFTVLGASAFTALIILPPWPFLFRKNPIVWHTPAEPQESGDKKKETKKTK",
    "output": "Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Dispensable for SPC enzymatic activity (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MANALIEDLKWRGLIYQQTDEEGIEELLNKEQVTLYCGADPTADSLHIGHLLPFLTLRRFQEHGHRPIVLIGGGTGMIGDPSGKSEERVLQTESQVEANVKGLSNQMHRLFEFGSDKGAKLVNNKDWLGQISLISFLRDYGKHVGVNYMLGKDSIQTRLEHGISYTEFTYTILQAIDFGYLNRELNCKIQVGGSDQWGNITSGIELMRRMYGQTEAYGLTIPLVTKSDGKKFGKSESGAVWLDPEKTSPYEFYQFWINQSDEDVIKFLKYFTFLEKEEINRLEQSKNEAPHLREAQKALAENVTKFIHGEAALKDAIRISKALFSGDLKSLSAKELKEGFKDVPQVTLSTKTTNIVEALIETGIASSKRQAREDVNNGAIYINGERQQSVDYELSSKDLIEDEITIIRRGKKKYFMVNYQS",
    "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIWHVQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDSTSDQKDMPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMIVGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVLSIYYYLKIIKLLMTGQNQEITPHVRNYRGSPLRSNNSIELSMIVCVIASTIPGISMSPIIEIAQDTLF",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAFALLRPVGAHVLYSDVRLLSEDEENRSESDASDQSFGCCEGLETTRRGPGPGGGRRASSGAGPVVVVRQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLMLGDAADDGQPCFRAAGGGKSAVPAADGRQPRSICTFCLSNQRKGGSRRDLGGSCLKVRGVAPLRGPRR",
    "output": "Early transcription factor that plays a key role in somitogenesis, paraxial mesoderm development and regulation of stem cell pluripotency. Essential for the mesenchymal to epithelial transition associated with somite formation. Required for somite morphogenesis, thereby regulating patterning of the axial skeleton and skeletal muscles. Required for proper localization of somite epithelium markers during the mesenchymal to epithelial transition. Also plays a key role in regulation of stem cell pluripotency. Promotes pluripotency exit of embryonic stem cells (ESCs) by priming ESCs for differentiation. Acts as a key regulator of self-renewal of hematopoietic stem cells (HSCs) by mediating HSCs quiescence and long-term self-renewal. Together with MEOX2, regulates transcription in heart endothelial cells to regulate fatty acid transport across heart endothelial cells. Acts by forming a heterodimer with another helix-loop-helix (bHLH) protein, such as TCF3/E12, that binds DNA on E-box motifs (5'-CANNTG-3') and activates transcription of target genes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLLVIGLGNPGKEYQYTRHNVGFIAIEKIANQYNSSFSTKKKFNCEIAETISDGQKIIFIKPTTYMNLSGKSVISVKTYYNIYPAKIFVIHDDIDLDTGRIKFKTGGGNGGHNGLKSIDGVIGNNYNRIRIGVGRPQNNQDVADYVLNHFSKPEYETVMQAIDRITSNFGLILENKLEEFKNKIA",
    "output": "The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MISKPDKNKLRVKRHKRVRGKISGTAARPRLNVFRSNANIYAQLIDDVAGVTLASASSHDAEVSGTKTEQATKVGELIATRGKAAGFEDVIFDRGGYLYHGRVQALAESARENGLKF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAEFVRAQIFGTTFEITSRYTDLQPVGMGAFGLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAACIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVKSLPKRERQPLASKFKNADPDAVDLLERMLVFDPKKRIRAGEALAHEYLAPYHDPTDEPVAEEKFDWSFNDADLPVDTWKIMYSEILDFHNIDQANDAGQVLVEGAVADGQQAFA",
    "output": "Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNAPLAGIWPWLPLLLTWLAPEVSSSWWYMRATGGSSRVMCDNVPGLVSRQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGTAKDSKGTFDWGGCSDNIDYGIRFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSPGTAGRVCNLTSRGMDSCEVMCCGRGYDTSRITRMTKCECKFHWCCAVRCQDCLEALDVHTCKAPKSADWAAPT",
    "output": "Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIDPKLLRNDLPMVVAALARRGFDFPEAEYQKLEDLRKASQVKSETLQAERNKLSQQIGKAKSKGEDCADLMAQAAQLESEQAAVEASFNETQKQLDTLLSSVPNLPDDSVPTGKDENDNPEIRRWGTPRTFDFTPKEHADLMQIGLDFTNGVKLAGARFTVLRGALSRLHRAIAQFMLDTHTEEHGYQEMSVPYLVNPQTIYGTGQLPKFEQDLFKTRLSDRDFYLIPTAEVSLTNLVAQEILEESVLPLQFVAHTPCFRSEAGSAGRDVRGMIRQHQFDKVELVHITTPEDSHAALERLTAHAERILQKLELPYRVILLCTGDMGFAARKTYDLEVWLPGQGKYREISSCSNCWDFQARRMQARFRAEGEKRPQLVHTLNGSGLAVGRTLVAILENYQQADGNILIPKALQPYMNGLDRITPSA",
    "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MINLGSYNLLRHEKDSFLEIIRRIKDGDNLLRNKFIDDFKPFILKCVSQLVGKKNDLTQSDEYSIALIAFNEAIESYDLDKKTKFVSFSKQVIKRRLIDYLRSTKKNNVAVPFSYFNDCNSSFNDSSTGNFEEKFLYDRNSDYSIDFEAREEIKNLELKICEYKMTIEDLIECSPKHRDTIILCLNVANIIIEDESLYQMFNKRKTLPYKELTERFNLCRRTLEKNRKFITAMVLILKSDLEVLKKYIYDTLGR",
    "output": "Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "ITCCTRGTCAQHC",
    "output": "Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKFIIKLFPEITIKSQSVRLRFIKILTTNIRNVLKHLEDDTLAIVRHWDHIELRTKDDNLGPEICDALTRIPGIHHILEVEDRSYSDMHNIFEQTLEAYRETLVGKTFCVRVKRRGKHEFSSGDVERYVGGGLNQHIESAKVNLTRPQVTVNLEVDQDKLILVKARHEGLGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGSAHEIGVKQVAHYLWNRFGSSHRVRFIAIDFEPVVGEILEKVEDGQMGVVLKRMMVRAASQVAERYGVQALVTGEALGQVSSQTLTNLRLIDNASDTLILRPLISHDKEHIINLARQIGTEDFAKTMPEYCGVISKSPTVKAVKAKIEEEESHFDFSILDRVVSEAKNVDIREIAQQSREQVVEVETVAELADTDVLLDIRAPDEQEEKPLKLDQVEVRSLPFYKLSSQFADLDQSKTYLLYCDRGVMSRLQALYLREQGYTNVKVYRP",
    "output": "Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAGKGNPVPGPHLNGFPVPTYSYFFPHMLGSLSPPALPGLPISGYSTPSPATIETQSTSSEEIVPSPPSPPPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHREKNCIINKVTRNRCQYCRLQKCLEVGMSKESVRNDRNKKKKDEKKPECIENYVLSPDTEQMINRVRKAHQETFPSLCQLGKYTTTNSSERRVALDVDLWDKFSELSTKCIIKTVEFAKQLPGFVTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLLCGDRQDLEQAEKVDILQEPLLEALKIYVRRRRPHKPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLESGATGSRPSGAPPGSCSPSLSPSSAQSSPPTQSP",
    "output": "Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSNASLVTAFILTGLPHAPGLDALLFGIFLVVYVLTVLGNLLILLVIRVDSHLHTPMYYFLTNLSFIDMWFSTVTVPKMLMTLVSPSGRAISFHSCVAQLYFFHFLGSTECFLYTVMSYDRYLAISYPLRYTSMMSGSRCALLATGTWLSGSLHSAVQTILTFHLPYCGPNQIQHYFCDAPPILKLACADTSANVMVIFVDIGIVASGCFVLIVLSYVSIVCSILRIRTSDGRRRAFQTCASHCIVVLCFFVPCVVIYLRPGSMDAMDGVVAIFYTVLTPLLNPVVYTLRNKEVKKAVLKLRDKVAHPQRK",
    "output": "Odorant receptor."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MCFGGRGKDDEAEASRSRELDKQIRADEKRLSKEVKLLLLGAGESGKSTILKQMKLIYAQGFSKNEKLEWRPVIFANILQSFRLIFDAMNEFNIKLEDEDNEKNMVQMMVDYEMRGDEPLPLEYFEPAKKLWQDSGVRQAIEKGNEFALHDNLQYFCSDLDRLWDRNYVPSDQDLLRSRLRTTGITETVFDLGQLTYRMFDVGGQRSERKKWIHCFENVNCLLFLVAISGYDQCLVEDKDGNQMNEALMLWESIANSHWFTKSALILFLNKIDLFKEKLPRSPITNHGFTDYHGPPDDSKQASKYFMDKFRALNRNPDKEIYGHFTNATDTNLLKITMGSVQDMIIQRNLKQLIL",
    "output": "Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MITLRNISFSYNGTKENNLCDISLHIPKGQCVLLCGASGCGKTTLTRLINGLIPHFFEGEFSGEAIINGMNSEEADIAQLSDSVGTVFQNPRTQFFNTDTDSEIVFGLENRGLPPEQLLSRLEKVTEDLQIQNLRERSIFELSGGEKQKIAFASVYAAAPDIFVLDEPSSNMDYHSIKELSELIKKIKLQGKTIIIAEHRIWYLMDIADRVIFMENGKIAHDMDIKTFVDLPEAQIKSMKLRCRNLADVKAETVNVSPDVSVSFGGHTFAVKDITVKLGHTSVLQDISFSTTGGEIIAITGENGAGKTTLARTLCGLTQEAAGSISFDGNPLSRKMRRERSYMVMQDVGHQLFTDSVYAECRLGIKDLPDPAIDEVLTELSLNRLKERHPLSLSGGQKQRLAVAVSVLCGKDILIFDEPTSGLDLKSMQEAGRIIKRLADDKKTVIVITHDIEFIKTICSRVLILSGGKIVKELCGEKKNELEMQLETF",
    "output": "Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDAEPFDEVDEYTTYPSLPASVICPVADTKTRYELSWQPSGHHPQEEGDDCAVVTLVYAAWALMASRMTSSERVVFDTIDGRPDRPAARPLRVLCASSQTVGEYLQALRAHTSSEESYMASPDCKSKRHPTSSTLIATRTSGDAKSSNGTIGNGLPSLAGYPLVLDLQLRGSRLQATAMSDSRCTEPWIVFRLLIRLEYCMKGLHEADSRTRLADIDLMSPDDVEQIWKWNGTLPAAVERCMHDMFEDQVYSQPLALAVDAWDGRLTYKELDELSEKLAGHLIDADVGPEVIVPLCFEKSMWMPIAMLGVLKAGGSFTLLEPSFPEQRLRTIVEKVNASVMISSPSNMSLSSRLLKRVVELDSCSVKSFSAHPSRPRNSQPSSTAMFAVFTSGSTGVPKGAILTHTNYSSALAYQLQPLGFTKDSRVFDFASYAFDVSVHNVFATLTSGACLCIPSDEDRHNDISKVMVDMRVTISHLTPSVTRLIDPDSQPFLKTMVFTGEPLSVDDATRWWGKVDVVNEYGPAECTINTVNSRPISPEAATNIGLPVGVAAWITDPENHQVLVPIGCVGELLVEGPLVGRGYIGDPIKTAASFIQDPKWLLRGVSGHPGRKGRLYKTGDLVRYCADGSLSYLGRKDAQVKIRGQRVHLGDVEHWTQVCMPEAQRVFADVIEPQAISPVPTLAVFVQSPEMGENTATNERPVQIRALRADVQAKLSQHLPSYMVPTVSFWMETLPMTPTGKMDRRMLRRIGSSFSAEQLAQARADRRDGPKRQPTCEMEERMRNIWARVLGMLPQDIHLESNFFHLGGDSIASMRVVAYARRLGIQVMVADVFQHPSLHDLAKNCSQTLARAPEDIPAFSLLGPHFNHALFVQDMSTRYALDPMTIQDAYPCTRLQEGLMFLTSKRPGDYIEQNVLELARDLSLEGLRNAWEQAVKAMPILRTRIAQHNHVGLVQLVLDDTADWDEAKGLEKYLAADRKRSMGLGEPLSRFALVRDEEGTCKWLVWTIHHAIYDGWSIRLVTDAVAEAYGGRSIPQGPQFQAFIKYVQDQDERAAVNYWQRNLQGFDSAPFPPNVPSVDQPVADAAVAHSFATPSGAHGCITTSMLIRAAWALVVGRMANSNDVVFGSTLHGRNAAVNGLDEMVAPTIATIPVRVRFCSTQYVPSYLQAITQEAAEMMPYEQTGLQRIAALSSDAEKACKFQTHVVIQPEDCIPGRSLLGQWRSDSQDQWFSTYALTVEVWLRSDDIFASAMFDSRTIQSWVVTGMLQRLEWTMHQLHHATPSQTLGEINMSSAEDLEQIWQWNERVPEPVNRCIHDLLADQVQARPDSPAICAWDGELTYRKLDELSTRMSHSLLQLGAGFHKGLVPLCFDKSMWTAVAILGVLKAGVGFILLDPHLPEQRMRDIVDQVGSKVIVTCPTREILCSRLAEATVAISWDYFSGQLDWTQQELPSVSPSSTAYVVFTSGSTGTPKGVVVTHANAVSAQHHQLEPMGHTPESRLFDFASYSFDVSISNIVSMLACGGCLCVPSESDRTDDMEKSIVSLRVNALDLTPSTLQLLSPERLPAVRQLTLGGEPLREADVEKWCGKTRICNAYGPSECTPTATINSNAMEPQMATHIGKGAGVVTWIVDADDHDELLPLGCTGELLLEGPLVGRGYFNDSAKTAAAFIEDPKWLLRGSISHPGRQGRLYKTGDLVKYNRDGSLAFVGRKDTQVKVRGQRVEPGEIEAVLRSHESVDGAVVVFHRLTDQELWLAAFVTTREDDGKIPQSQSLAHDETQLKQKRIQAWEEEFEGETYLAIGATEAENIGRDFVGWSSMYDGSEINKVEMNEWLDDTIATMLNGGPAGHVLEIGSGSGMMLFNLANHSLQSYIGVDPAMRAVDFTTKAAKSVPDLADKVNVFKGTAEDIMNLDMPIHSELAVMNSVVQYFPSQDYLFNIIQHLASLGSIKTIFVGDIRSHALHKEFMARRALHIAGKDASREEFSGIMENLLKGEPELLVDPGFFTSLPHRIHGVTHVEILPKRMKATNELSSYRYAAVLHVNSHGEQAKDGRAQDIGADEWIDYVSNGLDRQAVSGLLGTASRVAISNIPYSKTIYEREIVNAVEASKNIPKLERESEWLAAALQASQEHSSLCAFDLAELAQLAGYRVECSWARQYSQRGGLDAVFYCGGSGTDSERRTLFRFPTDHEGRPCHVLSTNPLEQQRKSKLRGDLEQLLRSKLPSYMVPQAIKILDKMPVNHTGKIDRSMLSESLQQKAPPTARKRLPSTAPERAMQQIWSKVLSIESSQIGLDDGFIKLGGNSLSAMKVVSMAREEGIRLEVADMFHHSTTSIAHLLQTAAAGVSESGAALPGVTSDRLLSDLARYDCTIAMAQSEAANKRLSATSHGGIRDTRLTVVLTGANGFIGTQILRQLLDHGRFSRVIAIVRGTSASKARQRAIDAAKNAQWWSEFYSSELEVWRGDLALPRLGLGKENWNTLADGTVDVFIHNGASVHFMKSYSALQAANVESTAQVLRVAAENPSMRVVYVSSARCCDPELEREEDVAKALADRPNGYTTTKFIAEALVKRAAARGLGRRDQFAVVSPGLVVGTPTEGVANADDWLWRMTAACIRVGVVNGEESDNWIPIADAAATATTVIETSLGRSSGIVTQVKGGLTMGEFWETLRAIGYTLRGEDSSTCMAAIRQDVEKNRDTHPLGALSDMLQDLADTARSQWADSWRTGGLSSPARLKLALVKSAGFLSKVGVLPLPDGNDEPAQARENLRAFTRSGG",
    "output": "Nonribosomal peptide synthase; part of the gene cluster that mediates the biosynthesis of peramine, a pyrrolopyrazine synthesized in association with the grass host that protects the plant from insect herbivory . The single multifunctional NRPS perA seems to be responsible for all catalytic steps in the biosynthesis of peramine . The condensation domain of perA is proposed to catalyze formation of a peptide bond between 1-pyrroline-5-carboxylate and arginine . The methylation domain of perA would catalyze the N-methylation of the alpha-amino group of arginine . The reductase domain is proposed to be responsible for reduction of the thioester and the cyclization to form an iminium ion resulting in release from the peptide synthetase . Deprotonation of this intermediate and oxidation of the pyrroline ring would give rise to peramine . This final oxidation to give the pyrrole functionality may be spontaneous ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEILLLAVALSMDCVALSMSNGAKCANYGIFRITKVSFVYGFFQGAMPIIGFFLGALFVGFIEQIDHFVAFAILGFLGVKMIFDSRENSDEITANLGLKELISGAVATSIDALAVGVTFSFTSLNIWFSCAIIAFVCFILSFAATFIGKKLGEIFKDKALILGGLILIFIGFKILITHLGIL",
    "output": "Probably functions as a manganese efflux pump."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNWHLLQARGITCVINATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI",
    "output": "Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVIKMSETGGNYDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDDRLIYTANDLKVGLFQDTSAF",
    "output": "Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRKSAAPKRPVVQDPVYKSELVTQLVNKILIGGKKSTAERIVYGALEICREKTGTDPVGTLEKALGNVRPDLEVRSRRVGGATYQVPVDVRPERANTLALRWLVTFTRQRRENTMIERLANELLDAANGLGASVKRREDTHKMAEANRAFAHYRW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLRVESLRKVYDSGDVALDDVSLTVSGSETVAIIGPSGAGKSTLVRCINRLVEPTSGTVWLDEREVTGLPEKQLPAVRRDMGMIFQEYNLIERLTVMENVLSGRLGYVSSWKGFRRKFPQEDVDRAFEILDRVGLSGLENNRADELSGGQRQRVGIARAVIQQPKIMLVDEPTSSLDPDTSRDVMDLLTEIASDEGVPVLLNIHEVDLAVEYADRIVGLADGRIVYDGSTDGLDEGIENKIYRNGRESARSSPSSEPALSDDTELHR",
    "output": "Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQEFKTDLRFQSSAVMALQEAREAYLVGLFEDTNLCAIHAKRVTIMPKDIQLVSRIRGERA",
    "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGQFISFMQEIPIFLQEALNIALVAVSLICIVKGLVNLYRCGLFQLMVFLVLAGRSCSEETFKIGMHTQFQEVSLSLSALLTNQSHELPMLCLANKTHLYLKSGRSSFKINIDSVTVLTRSADVFVHSPKLGSCFESDEEWVVAWWIEAIGHRWDQDPGLLCRNKTKTEGKLIQINISRADGNVHYGWRLKNGLDHIYRGREEPCFEGKQCLIKIQPEDWPTDCKADHTNTFRFLSRSQKSIAVGRTLKAFFSWSLTDPLGNEAPGGYCLEKWMLVASELKCFGTLQCQVQPKSRLRVCDMLRLFDYNKNAIKTLNEETKTRVNVLSHTINALISDNLLMKNKIRELMSVPYCNYTRFWYVNHTLSGQHSLPRCWMIRNNSYLNSSEFRNEWILESDFLISEMLSKEYSERQGRTPITLVDICFWSTEFFISTLFLHLIGFPTHEHIRGEGCPLPHRLNSMGGCRCGKYLPLKKPTIWHRRH",
    "output": "[Glycoprotein G2]: Class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induced upon acidification in the endosome.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSLAEFDADVVINAQNCIVGRVASEVAQRALGGETVAIVNVEDAVITGSEEDVMSVYETRSELGSDQGPAYPSRPDGIFKRAVRGMLPYKSDRGREALSNVRTYVGNPYDDDGEAIDGTTLDRLSNIKFLSLGEVSANLGATVTW",
    "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRTVVWQSLSEAQQESILERPAITEGANITAAVAQVIAKVRSEGDAALFELTEKFDRVKPASLRVSREEMDAAAARLSETMKQALEQAYNNISKFHKAQKAQPIKVETMPGVVCEQVTRPINKVGLYIPGGSAPLPSTVLMLGVPAQIAGCRKVVLCSPPPIADEILYVAKLCNIDEVYNLGGGQAIAAMAYGTETVTKVDKIFGPGNAYVTEAKRQVSNDFRGAAIDMPAGPSEVLVIADETADANFIAADLLSQAEHGPDSQVVLVTPSPVLADQVTDAVQKQLKVLSRASIAEKALASSLIIIAESLTQAVSISNYYGPEHLIVQTRNPRELVPLLDNAGSIFLGDWSPESVGDYASGTNHVLPTYGYTRTYSSLGLADFSKRMTVQELTADGLQLLAPTVVTMAEAEGLDAHKRAVTIRVEKLQKAQ",
    "output": "Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKTYYEKDANVELLKGKTVAVIGYGSQGHAQAQNLRDSGVEVVVGVRPGKSFEVAKTDGFEVMSVSEAVRTAQVVQMLLPDEQQAHVYKAGVEENLREGQMLLFSHGFNIHFGQINPPSYVDVAMVAPKSPGHLVRRVFQEGNGVPALVAVHQDATGTALHVALAYAKGVGCTRAGVIETTFQEETETDLFGEQTVLCGGVTALVKAGFETLTEGGYRPEIAYFECLHELKLIVDLMYEGGLTNMRHSISDTAEFGDYVTGSRIVTDETKKEMKRVLTEIQQGEFAKKWILENQAGRPTYNAMKKAEQNHQLEKVGAELREMMSWIDAPKELVKK",
    "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIESDSDTSDDAPQEYVSASANIPAQFELATAHMKATPEPQPTQQPDAEALHDDDPLTTTQDHPTGPSATASDTIDSTPQPMAPATLSASAVLPSLPSDTAALLETFSQQLQQSNVKCQLKFRPIGGATPSLKQSVYKIAETQQFGVVVKFLRKQLKIKNSQSSQIFCYISSFAPGLDETVGSLYNRYAIRGELTISYCLNQAFG",
    "output": "Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTLFDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG",
    "output": "Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQDLIKRTLPQDDALNQAIVNDLRSQNWAGFLNYSQVQQLCHNFELTTLKLAMHLLPLAASYSHTAISHFNVGAIAIGEQGDFYFGANQEFANSAIQQTIHAEQSAISHAWLRNERRISDMVVNYTPCGHCRQFMNELHGAEKISIHLPHSQNNPLHSYLPDAFGPKDLDIAAHLLAEENHDLVADHQDDLVNQAILAANQSHCPYSNSPHGIAILFKNSDVVTGRYAENAAFNPSLPALQTALNFAYLNDKKLSDIERIVMAEKALKLSHKTMAETLLSTLTSVELEYYSL",
    "output": "This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGRDTIADIITSIRNVDMDRKVTVRIASTNITENIVKILLREGFIENVRKHQESNKYFLVLTLRHRRNRKGTYRTILNLKRISRPGLRIYSNYQRIPRILGGMGIVILSTSRGIMTDREARLERIGGEILCYIW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MWQAQIFTLYPDFFPGPLNKGLYGKALTNKIWDLKVVNFREAAEDKHKTVDDTPFGGGSGMLLKADILAKSLDENKKEGERIFYLSPKGKKLDQKLALELSKEKSISLICGHFEGVDERLLSTRNIEELSIGDFILSGGETAAFVVLDSVLRLLPGVLGNEQSKNDESFENGLLEYPQYTKPQIWEEKSVPEVLLSGDHNKIKDWRLSQSEAITRVRRPDLWEKYKKN",
    "output": "Specifically methylates guanosine-37 in various tRNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MELTTRTLPTRKHIALVAHDHCKQMLMNWVERHQPLLEKHVLYATGTTGNLIQRATGMDVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVSTADFIIQSPHFNDAVDILIPDYARYLAERLK",
    "output": "Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATVERRVQVDPTDKRIHLQPQYEGDVGYGYGYGGRADYKSSGPSSNQIVALIVGVPVGGSLLALAGLTLAGSVIGLMLSVPLFLLFSPVIVPAAITIGLAVTAILASGLFGLTGLSSVSWVLNYLRGTSDTVPEQLDYAKRRMADAVGYAGQKGKEMGQYVQDKAHEAHDTSLTTETTEPGKTRRHT",
    "output": "May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil. Probably interacts with both lipid and phospholipid moieties of lipid bodies. May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFFEILIGASAKAVKDFISHCYSRLKSIYYSFKRWLMEISGQFKAHDAFVNMCFGHMADIEDFEAELAEEFAEREDEVEEARSLLKLLVAQKSKTGVTEAWTDFFTKSRGGVYAPLSCEPTRQELEAKSEKLEKLLEEQHQFEVRAAKKYIKEKGRGFINCWNDLRSRLRLVKDVKDEAKDNARAAAKIGAEMFAPVDVQDLYSFTEVKKVETGLMKEVVKERNGEEEKHLEPIMEEVRSIKDTAEARDAASTWITETVKLKNSTLNADELSLATIARYVENVGDKFKLDIASKTYLKQVASMSVPIPTNKDIKLKMVLQSPEARARREPLDVLDSVGFLEGLCTASGFESPFPILGLPEIAVTDGARLRKVSSNIRYLSQTHLGLVYKAPNASLHNALVAVERRVFTVGKGDKAIYPPRPEHDIFTDTMDYFQKSIIEEVGYCRTYPAQLLANSYSAGKRAMYHKAIASLRTVPYHQKDANVQAFLKKEKHWMTKDIAPRLICPRSKRYNIILGTRLKFNEKKIMHAIDSVFGSPTVLSGYDNFKQGRIIAKKWQKFACPVAIGVDASRFDQHVSEQALKWEHGIYNGIFGDSELALALEHQITNNIKMFVEDKMLRFKVRGHRMSGDINTSMGNKLIMCGMMHAYFKKLGVEAELCNNGDDCVIITDRANEKLFDGMYDHFLQYGFNMVTEKPVYELEQLEFCQSKPVSINGKYRMVRRPDSIGKDSTTLLSMLNQSDVKSYMSAVAQCGLVLNAGVPILESFYKCLYRSSGYKKVSEEFIKNVISYGTDERLQGRRTYNETPITNHSRMSYWESFGVDPKIQQIVERYYDGLTVSAQLQSVKVTTPHLQSILLSIPENHSQIEY",
    "output": "Probable polymerase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MCRAVAGVTRFVFTLALGVGSAHVTHAMKKKTSVSEQPEQRTYEVRTFGCQMNVHDSERLSGLLEDSGYQPAANGEEPDVLVFNTCAVRENADNRLYGTLAMVKPMKDRNPGMQIAVGGCMAQKDKDAVVDRAPWVDVVFGTHNIGSLPTLLERSAHNQRAEVEILDSLEEFPSVLPAKRESAYSGWVSVSVGCNNTCTFCIVPSLRGKEQDRRPGEILAEVQALVDQGVQEVTLLGQNVNAYGVNFADEDLPRDRGAFAKLLRACGEIEGLERLRFTSPHPAEFTDDVIDAMAETPNVCPQLHMPLQSGSDRILKEMRRSYRSKKFLGILDKVRERIPHAAITTDIIVGFPGETEEDFQATLDVVEKARFSCAFTFQYSPRPGTPAATMPDQIPKAVVQERYERLIALQERIQAEDNKELVGTTQELLVQETGGRKDAQRHRMSGRARDGRLVHFTPSEDVRPGDIVEVTITDARPFFLIADGPLVNHRLTKAGDMSGAGQTPTTAPIGVSLGVPTIGIKPQADATAAPKNVHEGCGCD",
    "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGGLPVSPKYVIKAKMEIKGSVEKHDIIGAIFGQAEGLLGSELDLRELQKTGRVGRIEVNTRSQDGTLVAEIEIPTNLDMAETAIIAATIESIDKVGPYPAKTEVVSIEDVRAEKRQKIIERAVELYKKLLESVPESRELVEEVLRRVRVAEIVEYGEEKLPGGPEVETSDTVILVEGRADVQNLLRHGYKNVIALGGATIPKSIKSLVENKKVILFVDGDRGGELIARNVINALKVDFVARAPPGREVEDLTAKEIARALQNKIPVDEFLQALEREKKQQKEVKAEIVVPPAKLIKSATKKNPEIAQEIVVPAEVYEKLEELKGTLEAVIYDENWQVVEKVPVRDLVNRLKEVERAAHVVLDGIITQRLVDVAYTKGLKSLIGVRIGEIIRKPDNIVLATFSSVKKSEENIQESVSTGESAQTSP",
    "output": "RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDDEESEAQGPK",
    "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (By similarity). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (By similarity). Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (By similarity). TUBB3 plays a critical role in proper axon guidance and maintenance . Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion . Plays a role in dorsal root ganglion axon projection towards the spinal cord (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTLVDRFLKYVSFDTQSDESTGLTPSTPKQMVFAEYLKTELESLGLEDITLDEHGYLFATLPANIDKKVPTIGFIAHMDTSPDMTGKDVTPRIVKGYDGTDIVLCAEENIILSPAQFPELLDHKGEDLIVTNGKTLLGADDKAGIAEIVSAIVYLKEHPEIKHGKIRIGFNPDEEIGEGAHKFDVGKFGCEWAYTMDGGEVGELEFENFNAAAAKITFKGRNVHPGYAKNKMINSIRVANQFIAMLPSTETPEQTEGYEGFYHLISIQGDVEQSTVSYIIRDHDRAKFEKRKEEIKRLVAQVNTEYGEGTATLELRDQYYNMREKIEPVMHIIDTAFAAMEAVGVKPNVKPIRGGTDGAQLSFKGLPCPNIFAGGLNFHGRYEFVPIQNMEKAMNVIVKIAELVASK",
    "output": "Cleaves the N-terminal amino acid of tripeptides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQKEIKPHMRKMLAYWMLEVCEEQRCEEDVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRETTPLTIEKLCIYTDQAVAPWQLREWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVLGLGACSMSADELTELLAGITGTEVDCLRACQEQIEAALRESLREAAQTAPSPVPKAPRGSSSQGPSQTSTPTDVTAIHL",
    "output": "Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Shows transcriptional coactivator activity with ATF5 independently of CDK4."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MHLLTLHLLLLLLGSSTKAGEIIGGTECIPHSRPYMAYLEIVTSENYLSACSGFLIRRNFVLTAAHCAGRSITVLLGAHNKTSKEDTWQKLEVEKQFLHPKYDENLVVHDIMLLKLKEKAKLTLGVGTLPLSANFNFIPPGRMCRAVGWGRTNVNEPASDTLQEVKMRLQEPQACKHFTSFRHNSQLCVGNPKKMQNVYKGDSGGPLLCAGIAQGIASYVHRNAKPPAVFTRISHYRPWINKILREN",
    "output": "Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME",
    "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSVGTVLLTALLALVGYLLMKWRSTMRHWQDLGIPCEEPHILMGSMKGVRTARSFNEIWTSYYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCAFGIECSSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPNLARRLHMKMTAEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKPLMVSQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCEKTTIPMTYNKEMFLIASNSGIYLKAERV",
    "output": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSLLCVRVKRAKFQGSPDKFNTYVTLKVQNVKSTTVAVRGDQPSWEQDFMFEISRLDLGLSVEVWNKGLIWDTMVGTVWIALKTIRQSDEEGPGEWSTLEAETLMKDDEICGTRNPTPHKILLDTRFELPFDIPEEEARYWTYKWEQINALGADNEYSSQEESQRKPLPTAAAQCSFEDPDSAVDDRDSDYRSETSNSFPPPYHTASQPNASVHQFPVPVRSPQQLLLQGSSRDSCNDSMQSYDLDYPERRAISPTSSSRYGSSCNVSQGSSQLSELDQYHEQDDDHRETDSIHSCHSSHSLSRDGQAGFGEQEKPLEVTGQAEKEAACEPKEMKEDATTHPPPDLVLQKDHFLGPQESFPEENASSPFTQARAHWIRAVTKVRLQLQEIPDDGDPSLPQWLPEGPAGGLYGIDSMPDLRRKKPLPLVSDLSLVQSRKAGITSAMATRTSLKDEELKSHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSCKHGAEDRTQNIIMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTKTIFGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQISVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWFEQFVLQWLDENEDVSLEFLRGALERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNVQQLRVQLEKMFEAMGGKELDLEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDARASAAQDADSVLRPLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTDQTGTQLIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVLDLALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQGSGVDDPVGEVSIQVDLFTHPGTGEHKVTVKVVAANDLKWQTAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYELQICVKDYCFAREDRVLGLAVMPLRDVTAKGSCACWCPLGRKIHMDETGLTILRILSQRSNDEVAREFVKLKSESRSTEEGS",
    "output": "Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP) (By similarity). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity). In collaboration with UNC13A, facilitates neuronal dense core vesicles fusion as well as controls the location and efficiency of their synaptic release (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAQPLRHRSRCATPPRGDFCGGTERAIDQASFTTSMEWDTQVVKGSSPLGPAGLGAEEPAAGPQLPSWLQPERCAVFQCAQCHAVLADSVHLAWDLSRSLGAVVFSRVTNNVVLEAPFLVGIEGSLKGSTYNLLFCGSCGIPVGFHLYSTHAALAALRGHFCLSSDKMVCYLLKTKAIVNASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMKILSEVTPDQSKPEN",
    "output": "Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIQEQTYLKVADNSGGKIVKCIKVLNGTNKKYANIGEIIKVVVKTANFKSKIKKSQVLKAMIIRSKTGIKRLDGTIIKFNDNSVILLNNNEQIISTRVFGIILRELKNEKFAKLISLSNEII",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI",
    "output": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MADEESSSSSLLSKDLKLPPKTARDIGSVDIKEDEDPFGEISTDARARQRLVSEGSTTAEAEEKDLKETCRVAFDKITQYLNGELTASLEDYTLLEQLNNLTTDKYKEMSTMTKSLITTMEKLDDKYKSLQPYLEQIDRIEDSVSSLEQAAYRLDAYSKKLENKFKRLERR",
    "output": "Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). May also participate in the coupling of lysosomes to microtubule plus-end-directed kinesin motor. May also play a role in intracellular vesicle trafficking."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTTETLTQLEQHELFLRRHIGPGADQQQEMLNFVGAESLEDLTAQIVPGAILLNRDLAVGDSCGEAEGLAYIRKIADKNKVFKSYIGMGYHGTEVPSVIQRNVLENPGWYTAYTPYQPEIAQGRLEAILNFQQVSMDLTGLDLASSSLLDEATAAAEAMALSKRVSKAKKANIFFVADDVFPQTIDVIKTRAECFGFEVVVGPAEEAVNYELFGALFQYTNRVGQICDHTELFAKLHEKKALVSVAADIMSLVVLKSPGSMGADVVLGNSQRFGVPMGFGGPHAAFFVTRDEYKRSLPGRIIGVSQDTRGNRALRMAMQTREQHIRREKANSNICTAQVLLANMASFYAVFHGPQGLKVIAERIHRLTDIVAAALTAKGVELVNNTWFDTLSIKGLDVTAVQARALATGLNLRIDSDGVIGVSLSETTTRSDVAELFDVLLGEGHGQDAAALDAAIIANGSSSIPSELVRKDAILTHPTFNRYQSETEMMRYIKRLENKDLALNHSMISLGSCTMKLNAATEMAPITWPEFGNMHPFCPQDQAQGYAQLLEELSTWLVDITGYDAVSLQPNSGAQGEYAGLLAIKQYHESRGDAHRNICLIPQSAHGTNPASAQLAGMKIVVTACDKAGNIDMADLKAKAAEVADNLSCIMVTYPSTHGVYEETIGEICEVIHQHGGQVYLDGANMNAQVGLTSPGFIGADVSHLNLHKTFAIPHGGGGPGMGPIGVKKHLAPFLSGHSVVKHGLESDNNGAVSAAPFGSAGILPITWMYIKLLGKKGLRQSTQVALLNANYVMKKLSAHYPVLYTGRNDRVAHECIIDLRPLKEASGVTEMDIAKRLNDYGFHAPTMSFPVAGTLMIEPTESESKVELDRFIEAMVSIRGEIAKVEAGEWPVDNNPLHNAPHTLADIMDPAFDSRPYSREEAVFPTNAVKANKFWPTVNRIDDVYGDRNLMCSCAPVSDYE",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASASTSSSNESESQSVLTWEQVSRLNDVLTEAVPVHGRGNFPTLEVRLKDIVQMVRNRLELRGIMVKDVRLNGSTASHVLVQDIGWSYKDLDVIFRVDLPREEEFQLIKDVVLSTLLDFLPEGVNKEKITPMTLKEAYVQKLVKVYTDQDRWSLISLSNNNGRNVELKFVDSIRRQFEFSVDSFQIILDSVLSYYDLSENPMSQHFHPTVVGESMYGDFVEALGHLTNKTIATKRPEEIRGGGLLKYCNLLVREFKPTDPDEFKALERYMCSRFFIDFPDIVEQQRKLEAYLQSHFIGEERNKYNYLMILRRVVNESTVCLMGHERRQTLNLISLTAFRVLAEQNAIPDVSSVTCYYQPAPYVKDLNFNNYYVASCNQSIPTWLPCN",
    "output": "Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and enhances mRNA stability and gene expression."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFDIQEELKKLPDKPGVYIMKDENGEIIYVGKAVVLKNRVRQYFQSLSNQTPKVRAMVAHIKEFEYIVTDTELEALILECNLIKKHRPKFNILLKDDKNYPYIKVTMNEDFPRILMTRRVEKDGAKYFGPYTSAYAVRETIDLVKKLFPVKTCSKVLPRDIGKGRPCLNYHIYQCLGPCQGNVSKEEYRFMMQDVCNFLGGRQEDIIKKLEKDMKEAADNLEFERAARIRDKINSLKHIAEKQKIISTAMEDQDVIAFAKSETDSCIQVFFIRGGKLIGREHFILEGTSDVSDSELMTAFVKQFYSSAAYVPGQIILQEDIDEMEIIEKWLSGKRGTKTYIKVPRRGEKLKLVEMVSKNALIELNQFKERIKKEAALAKEGMEKLKELLNLDRLPRRIEAYDISNTGSTEIVGSMVVFENGSPKKSDYRRFKIKSINVQNDYQSMQEVIFRRLKRAQKEMTEKDEGGGKDVGEKGAGFGTLPDVLLVDGGTGHVNAVRSVLEELDFNIPVYGMVKDDNHRTRGLVTGEREFDLSKDIVLLRFVTAIQDEAHRFALEYNRKLRAKRYSGSVLDNIEGVGPKRKKELIRHFGSVKAIKEAEPGEIAKVKGISRDLAQKIYDYFRQQE",
    "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLITFEGIDGAGKSTQVAKLVAYLKQQSTPLLSLREPGGTPTAESIRSLLLDNRKSITPIAELLLFSASRAELVETLIRPALAEGKTVILDRFFDSTTAYQGHGRGISLEQLHSIIALSTGDLLPDVTFYLDLEPEEALRRAFSRSGLPLDFAAQSNESDRMEQAGIAFYHKVRNGYLTLMQQHPSRFVALDATQPPDTLHQHIIAEVETRLKLHISPLVAP",
    "output": "Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRILLTNDDGIHAPGIHALWRIFDDWADIFVVAPDTERSATGHGITVHQPLRVEKLSFANPHCHGWAVNGTPADCVKLAMEELLAEPPHIVISGINRGPNLGTDVLYSGTVSAAMEGVIYGVPSIAVSVTGWHTADYTVAAETTRLLCEKLVARGLTPDTFLNVNVPDLPRERIAGIQVTKLGSRRYQNIFDKRTDPRGRTYYWMAGEVHDVDAGEGTDISAVNAGAISVTPIHFDLTNYSLIQEVSDWLGGGSSPFADRNKKDDVETKRKA",
    "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSTEVNANQSPNAESRQEAARSGERDKALNLVLGQIERNFGKGSIMRLGDASRMRVETISTGALTLDLALGGGYPKGRVVEVYGPESSGKTTLTLHAIAEVQRRGGVAAFVDAEHALDPVYAASLGVDVENLLVSQPDTGEMALEIVDQLIRSAAVELVVVDSVAALTPRAEIEGEMGDHVIGSQARLMSQAMRKITGNIGKSGCTVIFLNQLRLKIGVTYGNPETTTGGNALKFYASVRLDIRRIQTLKRGTDEYGIRAKVKVAKNKVAPPFRIAEFDILFGKGISTIGCLLDLAEETNIVARKGAWYSYEGDNIGQGRDNTITWLEQNTEAKEKIEKLVRQKLTEGSEVSSNSMRPLTTANRKAA",
    "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGDGALIVAVAIKGNNSKTKGVVRWALQEFASQEHVVFKLLHVQPRDSNSVSTTRKDLTTSVYKKDVDRKTREMLLPSRDMFVHREVQLDIMVLESDDIADAISKAVQDHGISELVIGASSSIIFSWKLKRSNLSSRIADATPRFCSVHVISKGKLLNVRKSDMDTETSIADDRSESRFSSDSHSGTVSSTSSHQFSSTPLLFQRIQALTTVNQKVGTNIGKQNNEPHHHHHNRAGSLDVDESKLLNQKGFYRTSSSGIGYGGSDISSWRSSQMEEASSSSTYSDPTSSSSQIHKDFELEKLKIELRHIKGMYAVAQSEVIDASKKMQDLNQRRSEEATRLKNLTIREEEADEVVEMERERQEDAENEAELVRECIERETEERLEAEARAEEVRKEKQRLEDALEGGPLQRQQYMKFEWEEIVEATSSFSDELKIGVGGYGSVYRCNLHHTTVAVKVLHSDKSSLTKQFHQELEILSKIRHPHLLLLLGACPERGSLVYEYMHNGSLEERLMKRRPNVDTPQPPPLRWFERFRIAWEIASALYFLHTNEPRPIVHRDLKPANILLDRNNVSKIGDVGLSKMVNLDPSHASTVFNETGPVGTFFYIDPEYQRTGVVTPESDIYAFGIILLQLVTARSAMGLAHSIEKALRDQTGKFTEILDKTAGDWPVKEAKEMVMIGLRCAEMRKRDRPDLGKEILPVLERLKEVASIARNMFADNLIDHHHNAPTHFYCPITKDVMENPCVASDGYTYEKRAIKEWLQKNHKSPMTDLPFPSDSLLPNHSLLSAIKEWRSQLIK",
    "output": "Functions as an E3 ubiquitin ligase."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKLLVEKTNEKAIIPFQAHEGDAGMDLFSVEEITLKPMERKLIHTGIKIQLPKDTEAQIRPRSGLALKHGITVLNTPGTIDEGYRGEIGIILINLGSEEFKVEEGMKIAQMVIKPTLTLKVEEVVELTETTRGENGFGSTGV",
    "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLYNLLLPHIHNSHIANLFHYITFRSGLAIIITLSLSFITGPILIKFLRSLQKNGQPIRSDGPESHQTKVGTPTMGGIMIILSSCLSTLLLADLTNKYTWITLFGFISFGIIGFMDDYAKVTKNNHYGVRGKSKLLLQGIISFIICVLLEYLDKSPSHLLNVPFFKNLSLDLGYFYIVFAIFVIVGSSNAVNLTDGLDGLATVPIAFTAGSFALISYLVGNLIYSNYLQLTYIPNTGELTVLCAGLVGSCLGFLWFNAQPAEVFMGDTGSLSLGGVLGIISVITKHEIVLAIVGGLFVIETASVILQVYYFKATKGKRIFKMAPLHHHFEKHGWAESKVVIRFWIISVIFALIGLSSLKLR",
    "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKKIEAWLSKKGLKNKRTLIVVIAFVLFIIFLFLLLNSNSEDSGNITITENAELRTGPNAAYPVIYKVEKGDHFKKIGKVGKWIEVEDTSSNEKGWIAGWHTNLDIVADNTKEKNPLQGKTIVLDPGHGGSDQGASSNTKYKSLEKDYTLKTAKELQRTLEKEGATVKMTRTDDTYVSLENRDIKGDAYLSIHNDALESSNANGMTVYWYHDNQRALADTLDATIQKKGLLSNRGSRQENYQVLRQTKVPAVLLELGYISNPTDETMIKDQLHRQILEQAIVDGLKIYFSA",
    "output": "Probably involved in cell-wall metabolism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRLEDLQEELKKDVFIDSTKLQYEAANNVMLYSKWLNKHSSIKKEMLRIEAQKKVALKARLDYYSGRGDGDEFSMDRYEKSEMKTVLSADKDVLKVDTSLQYWGILLDFCSGALDAIKSRGFAIKHIQDMRAFEAGK",
    "output": "Plays a role in viral DNA synthesis by promoting enzymatic activities of UvsX recombinase, by promoting UvsX-ssDNA filament assembly, and by helping UvsX to displace bound gp32 from ssDNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "WIMGHMVNAIYQIQEFVALGANSIEFDINFDTDANPIYTYHGVPCDCFRSCLHYEYFSDFLKALREHTLPGNPKYKENLVLFVFDLKTNSLYDSQAYAAGQKLAENIFQYYWANGEGMPVSGYLVLSIPNLQHYDLIKGFRETIKAKGHSELLNRVGYDFSANDNIPDVENAYKKVGIVNHVWQSDGITNCISRGLTRAKEAVSERDGGGVINKVYVWTIDKYQSMRDALDAGVDGIMTNYPDVLVEVLKEDAYKDRFRLARNYDDPFETFKV",
    "output": "Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity). This toxin acts on sphingomyelin (SM) (By similarity). It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity). It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity). Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRANVLKRKLSLRIKRKKRIRAKISGTQALPRISVFKSNRTLYIQAIDDVKAVTLAAVDGRKIGVKANKEGAKKIAAEFAKALKAKNIEEAVFDRNGYLYHGVIAVLAEALRENGIKL",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPITSSPDLFYLNDCDVVYWYDLTRLVCHYVNLTERDLLANEREKFLTSLDLLTAQITYVYMLFRNLRLVEDSFKKTLKKLIYTLSRFSINANIWFHSTLFEEREAIASQKDPERRSPLLQSILGTFQKFHFLLRLLHFLSNPNELTILPQLTPRFFKDSFNTISWNNPFLRKRLNQHMSHDLPRQMIKAVAGASGIVAENIDEIPASKQGTSCSSETSHHSPSAPFQRRRRGTIFSNVSGSSDESDTIWSKRKKPYPLNEETLSLVRARKKQLDGKLKQMIKSANEYLSNTANFSKMLNFEMNFKTYEEVSGTIPIIDILENLDLTIFLNLRELGDENRVFDEDVAIDDEDEEFLKHSLSSLSYILSDYFNMKQYFHDVVVKFIIVAQHLTLEDPFVFSPMQNDLPTGYYEPMKPSSLNLDNAKDKKNGSQNTDIQEEEDEYEPDPDSLILFHNLINQDSDFNDLKFFNLAHVFKKSCDDYFDVLKLAIEFVNQLILERENLLNYAARMMKNNITELLLRGEEGYGSYDGGETAEKSDTNAVYADSDTKDNDEWRDSQVKLPRYLQREYDSELIWGSNNRIKGGSKHALISYLTDNEKKDLFFDITFLITFRSIFTTTEFLSYLISQYNLDPPEDLCFEEYNEWVTKKLIPVKCRVVEIMTTFFKQYWFLGYDEPDLATLNLDYFAQVAIKENITGSVELLKEVNQKFKHGNIQEATAPMKTLDQQICQDHYSGTLYSTTESILAVDPVLFATQLTILEHEIYCEITIFDCLQKIWKNKYTKSYGASPGLNEFISFANKLTNFISYSVVKEADKSKRAKLLSHFIFIAEYCRKFNNFSSMTAIISALYSSPIYRLEKTWQAVIPQTRDLLQSLNKLMDPKKNFINYRNELKSLHSAPCVPFFGVYLSDLTFTDSGNPDYLVLEHGLKGVHDEKKYINFNKRSRLVDILQEIIYFKKTHYDFTKDRTVIECISNSLENIPHIEKQYQLSLIIEPKPRKKVVPNSNSNNKSQEKSRDDQTDEGKTSTKKDRFPKFQLHKTKKKAPKVSK",
    "output": "Promotes the exchange of Ras-bound GDP by GTP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSQITIALTKGRIEKDTVKLLTQAGFDMSFMADKGRSLIFESPDSRFRFLLVKGPDVTTYVRHGVADLGIVGKDILFEHPTGYLELLDLNFGLCKFSLASVPSYDPHDHKRKRIATKYPTVATDYFNQKGEDVEIISIQGSVEISPVLGLADAIVDIVETGHTLSANGLLVFEDICRVSARLIANQASLKNNPDIMPFVAKIESLVGRREVAFK",
    "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSAGGPRVGSVSVDSYLFSLPLVALNVGVRRRLSLFLNPRTTAAADWTSLAEEMGFEYLEIREFETRPDPTRSLLDAWQGRSGSSVGRLLELLALLDREDILYELKDRIEEDCQKYIRNQQKQESEKPLQVARVESSVPQTKELGGITTLDDPLGQTPELFDAFICYCPSDIEFVQEMIRQLEQTDYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGVQQKRLIPIKYKAMKKDFPSILRFITICDYTNPCTKSWFWTRLAKALSLP",
    "output": "Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. Upon TLR8 activation by GU-rich single-stranded RNA (GU-rich RNA) derived from viruses, induces IL1B release through NLRP3 inflammasome activation (By similarity). MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTPLQILISNDDGVLAEGVRCLAAAAASRGHRVTVVCPDHERSATGHGLTIHTPIRAERVDELYGPGVKAWSCSGTPADCVKLALSELLAEKPDLVLSGVNHGPNLGTDVFCSGTVAAAMEGTLEGLPALAVSVACFQWRDFQAAAQLAMDVAENALADHWPNNLLLNLNIPPCHLEQMGSLRWTRLSIRHYEEQFSRRVDPHSRTYFWLAGEVVKDLETAGDGPRDWPSDVAQIETNSPSLTPIQPDLFWRGDLSALPAACVANQPVR",
    "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGKAAAVGTAVVVAAAVGVAVVLARRRRRRDLELVEGAAAERKRKVAAVIEDVEHALSTPTALLRGISDAMVTEMERGLRGDSHAMVKMLITYVDNLPTGNEQGLFYALDLGGTNFRVLRVQLGGKEKRVVQQQYEEVSIPPHLMVGTSMELFDFIASALSKFVDTEGDDFHLPEGRQRELGFTFSFPVSQTSISSGTLIKWTKGFSINDAVGEDVVSELGKAMERQGLDMKIAALVNDTVGTLAGGRYADNSVVAAIILGTGTNAAYVENANAIPKWTGLLPRSGNMVINTEWGSFKSDKLPLSEFDKAMDFESLNPGEQIYEKLISGMYLGEIVRRILLKLAHDAALFGDVVPSKLEQPFVLRTPDMSAMHHDSSHDLKTVGAKLKDIVGVPDTSLEVRYITSHICDIVAERAARLAAAGIYGVLKKLGRDKMPKDGSKMPRTVIALDGGLYEHYKKFSSCLESTLTDLLGDDVSSSVVTKLANDGSGIGAALLAASHSQYAEID",
    "output": "Fructose and glucose phosphorylating enzyme . Functions as glucose sensor for plant growth and photosynthesis . Is essential for pollen development, germination, and tube growth . Its activity is necessary for the starch utilization pathway during pollen germination and tube growth, as well as for starch biosynthesis during pollen maturation ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDEPTILLTNDDGIESAGLRAVYDGLSTVGDVTAVAPAEDQSAVGRAISHEVTVHEHELGYAVEGTPSDCVVAGLEALVTDTDLVVAGCNRGANLGAYVLGRSGTVSAAVEATFFDVPAMAVSMYIPVREDAAFADIEANGDSYREAAKATTYLADHAVDAGVFEQCDYLNINAPVAEWGDAQMTVTRPSHLYEMDAEQDGDAVTLHDRIWEHMADGDIPDPEGTDRRAVVDGKVSVSPLTAPHTTEHHEALDAIAETYEPDDGGEAAD",
    "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPVRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQIVIQNINDLVKEAGKPRWDWQQEAVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSETIAALVAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDSFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPEMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNFVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISQFAPRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRVRLSIKEATEQSQPAAAPEAPAAEQGE",
    "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "STGSLGLDLALGVGGLPRGRVVKIFGPESSGKTTLCLEAIAQCQKNGGICAFIDAEHAFDPVYARKLGIKVEELYLSQPDTGEQALEICDTLVRSGGVDMVVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGHIKRTNTLVVFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGQIKKGDDVIGNETKVKVIKNKVAPPFRQAEFDILYGEGVSWEGELIDL",
    "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSAETAAANTATAPVPEVQEQESSKSKQVNLTPAPLPTSSPWKLAPTEIPVSTISIEDLDATRKKKNRTPTPKSSTATKWVPIKASITVSGTKRSGSKNGASNGNSNKSKNNKTAASSTSSSNANRKKKHHQHNAKKQQQMKKDGFESAVGEEDSKDATSQENGQSTQQQQPPHHRNHHHSHHHNSNGPQRRKFHNSNNAGMPQNQGFPPQFKPYQGRNARNNNNNRSKYHNHFHHNQQHPQQPMVKLQQQFYPVQPVLMAINNIARQIEYYFSEENLTVDNYLRSKLSKDGFAPLSLISKFYRVVNMSFGGDTNLILAALREIVANEAATVNVAEGTLAAKEGDNVTGEAKEPSPLDKYFVRSKSWSNWLPETFETEINIEKELVGDALDQFMISLPPVPQQEEESSTELASQEQETKEDSAPVAAGESESSL",
    "output": "May overlap in function with tropomyosin and may be involved in organization of actin filaments. Acts as a multicopy suppressor of RHO3 mutation. RNA-binding protein which may modulate mRNA translation. Involved in heme regulation of HAP1, as a component of the high-molecular-weight complex (HMC)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQIQFLGTGAGQPSKARNVSSLALKLLDEINQVWLFDCGEGTQNRILETTIRPRKVAKIFITHLHGDHIFGLPGFLSSRSFQSSEEQTDIDIYGPVGIRSFVLASLKVSGTRLPYRIHFHEFDVDTVGQVLETDKFTVFAEKLDHTIPCVGYRVIQKDLEGTLDAEALRAAGVPFGPLFGKIKNGQNVTLEDGTEIIASDYISPPRPGKVVTILGDTRKCHASVRLAVNADVLVHEATYGKGDEKIARKHGHSTNMEAAQVAKDAGVKQLLLNHISPRFLSKDISQLRKDASTIFEQVHIVKDLEEIEL",
    "output": "Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MALNDFHVSEPYTLGIELEMQVINPPGYDLSQDSSTLIDAVKPQLTAGEIKHDITESMLEMATGVCRDIDQAAAQLSAMQHVILQAASEHHLGICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCANGDDAIYLLHGLSHFVPHFIALSAASPYMQGADTRFACARLNIFSAFPDNGPMPWVSNWQEFAGLFRRLSYTTMIDSIKDLHWDIRPSPAFGTVEVRVMDTPLTLDHAINMAGLIQATAHWLLTERPFKPQEQDYLLYKFNRFQACRYGLEGVLTDAYTGDRRRLADDTLRLLDNVTPSARKLGADSAIDALRLQVKKGGNEAQYMREFIADGGSLIGLVQKHCEIWAGQ",
    "output": "ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLHNIRIVLVETSHTGNMGSTARAMKTMGLTNLYLVNPLVKPDSQAIALSAGASDVIGNATIVDTLDEALAGCSLVVGTSARSRTLPWPMLEPRECGVRSAREAEHAPVALVFGRERVGLTNDELQKCHYHVAIPANPEYSSLNLAMAVQILAYEVRVAFLDRQQAAAPIVEEEEAPYPLVDDLERFYLHLEQVLSHTGFIRQAHPGQIMSKLRRLFTRARPEAQELNILRGMLTSIEKQDKYPQRGADGSEHNGKN",
    "output": "Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDVLFSIAKTVSDLKKKVVVGTIYTNVEDIIQQTNELIRTLNGNTFHTGGIGTQPQKEWNFQLPQLGTTLLNLDDNYVQATRSVIDYLASFIEAVCDDEIVREASRNGMQPQSPTLIALASSKFKTINFNNSSQSIKNWSAQSRRENPVYEYKNPMVFEYRNSYILQRANPQYGNVMGLRYYTASNTCQLAAFDSTLAENAPNNTQRFIYNGRLKRPISNVLMKIEAGAPNINNLTILPDPTNQTTWLYNPDQLMNGTFTIEFYNNGQLVDMVRNMGVVTVRTFDSYRITIDMIRPAAMTQYVQRLFPQGGPYPYQAAYMLTLSILDATTESVLCDSHSVDYSIVANVRRDSAMPAGTVFQPGFPWEQTLSNYTVAQEDNLERLLLVASVKRMVM",
    "output": "Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTASPKNEMSTVFKRLMTYVMPMKGMLTLSILGLIVYGLVDAAFIAFIKPFIDEGFSQNPTVVAGVELPTSGGFSANKDVMLMAPLVVIGMFTLRGVANFVSTYCISYLSAQLIMDMRQQVFEHYLRLPVSYIDRENSGNLISRVTFDTEQIARASGSALISIVRDSITVIGMLALMFFYSWKLSLCILVIGPLMGVVISIVSKRFRKVSVQIQSAMGGVTATTEQMIKGHKNVLSFGGQETESKRFYEVNDRNRYQNMKLAMAQSVSQPVIMIIGSFALAFVLYAASLDSMKLELTAGTFAAILGAMLAMLQPIKNLTRVNAEFQRGIAACTTVFELLDTLPESDTGAHQVERVQGHLRFDNVSFSYPGQAKPALNNIDFDVKPGKTVALVGRSGSGKSTMASLITRFYTGLEQGDIRLDDVSIYDYSLKSLRSQVALVSQQVTLFNDSIANNIAYAYPGEVSREQILKAATLAHAMEFIEQLPEGLDTQVGENGVLLSGGQRQRIAIARAMLRDAPVLILDEATSALDTESEKAIQLGLDNLRHNRTSIVIAHRLSTIESADEILVIDQGKIIERGTHASLIEKKGAYAGLYQMQFGE",
    "output": "Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSIEVRNVSKNFNAFKALNNISLDIQSGELVALLGPSGCGKTTLLRIIAGLETPDDGSIVFHGEDVSGHDVRDRNVGFVFQHYALFRHMTVFDNVAFGLRMKPKSERPNETRIAEKVHELLNMVQLDWLADRYPEQLSGGQRQRIALARALAVEPKVLLLDEPFGALDAKVRKELRRWLARLHEDINLTSVFVTHDQEEAMEVADRIVVMNKGVIEQIGSPGEVYENPSNDFVYHFLGDSNRLSLGDEGHVLFRPHEVSLSRQEIEDHHAAEVRDIRPLGATTRVTLKVEGQNELIEAEVVKDHDSLVGLAKGETLFFKPKVWQKL",
    "output": "Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKALAAVNGPIADALVGKDAKDQATIDQIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGVFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEAVRMGAEVFHNLAKVLKSKGYNTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYKLGTDITLAMDCAASEFYDAEKKEYNLKGEGRIFTSNGFSDFLEELTEKFPIVSIEDGLDESDWEGFAYQTEKLGKKIQIVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGSRAPFNGLKEVKGQA",
    "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPRLERNVYKGLITSLSRKKPSNSLAVKESPLLTKFERWSGKRMKLFFESEDSFEHYGLRDLKLPHNMLANKLASPIRAERNTRYRIPKEFLIKLNLYKDATNNVLQLKANFNGVTGLGTTYIHNNKKCLEMKFCDISRWSSRQPLKVPPLPIVADKSALLKDYENQLIRELNECFSKLKTTSKHDHNTVKLYVSTENNLLMDVDTQGSLCINLQSITDKLPHTMLETVTNAPIHISAYSNMDFLTTLHRLLGYYRHRNR",
    "output": "Required for respiratory activity and maintenance and expression of the mitochondrial genome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDTKTHSLPITHTQLHSNSRPQSRTCSQCTCTHHRQTFSQSCRQSQRGSRSRSSSQSPATHQNPTGAHSSSGLQSQSPNASPPPKRHKKTMNSHHSPTRPTILHSSCPKNRKNLEGKLNKKKMAKRIQQVYKTKKRS",
    "output": "Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKTLSAKPAEVQHDWYVVDASGKTLGRLATEIARRLRGKHKTSYTPHVDTGDYIVVINAEQVQVTGKKSLDKKYYRHTGFPGGIRETNFEKLIAHKPEAVLEKAVKGMLPKGPLGYAMIKKMKVYAGTEHPHAAQQPQVLDI",
    "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPRSTWFKALLLFVALWAPLSQAETGWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDELANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMTPQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPELNPYIPDDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSARNQVMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMINANGYTQRLPQLFQALLEGYFSYTATEEQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSITLKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYAVFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQAVITQMLQAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVVEPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE",
    "output": "Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKRDYYEILGVSRSADKDEIKKAYRKLALKYHPDKNPDNKEAEEKFKEANEAYEVLSNDDKRRRYDQFGHAGVGSSAASGGGPGGFGGGGYADINDIFEMFTGGGRARGGGSPFSGFEDIFGGGFSGGGGRRARSTGIHGTDLKIRLKLTLEEIAKGVEKTLKIKKQVVCSECNGTGSKSGKTETCQTCHGSGEVRQASKTMFGQFVNIVACPTCGGEGQVVKDRCTSCYGEGIKQGEVTVKINVPAGVQDGNYLTLQGQGNAGPRGGAPGDLIVIIEEKPHDQFKRNGDDIIYDLAVGFPDLVLGTKVDVPTLDGHVKLTVPAGTQPNTMLRIGGKGIGHLKGGGSGDLYVRVNVFVPKDVSGKDKEMLKELKKSSHISPNHGEQDHEKSIFEKAKDIFG",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRILKSHPLLKIVNSYIIDSPQPANLSYLWNFGSLLALCLGIQIVTGVTLAMHYTPSVSEAFNSVEHIMRDVNNGWLVRYLHSNTASAFFFLVYLHIGRGLYYGSYKTPRTLTWAIGTVILIVMMATAFLGYVLPYGQMSLWGATVITNLMSAIPWIGQDIVEFIWGGLYTDEPQCGDVLLKILLNAGKSPILGFAYDLFFIIVLLIGVKIAMTRGKSAGVRSLHTSEASQRLHAGDLTYAYLVGLFEGDGYFSITKKGKYLTYELGIELSIKDVQLIYKIKKILGIGIVSFRKINEIEMVALRIRDKNHLKSFILPIFEKYPMFSNKQYDYLRFRNALLSGIISLEDLPDYTRSDEPLNSIESIINTSYFSAWLVGFIEAEGCFSVYKLNKDDDYLIASFDIAQRDGDILISAIRKYLSFTTKVYLDKTNCSKLKVTSVRSVENIIKFLQNAPVKLLGNKKLQYLLWLKQLRKISRYSEKIKIPSNY",
    "output": "Mitochondrial DNA endonuclease and mRNA maturase involved in intron homing and required for splicing of the cytochrome b (cobA) gene intron, containing its own coding sequence. The protein stimulates the intrinsic ribozyme activity of the intron through binding to and stabilizing specific secondary and tertiary structure elements in the RNA. As an endonuclease it introduces a specific double-strand break at the junction of the two exons the cobA gene and thus mediates the insertion of an intron, containing its own coding sequence (group I intron), into an intronless gene. Recognizes with limited specificity and cleaves the sequence 5'-GAGGAGGTTTCTCTGTA-3'. The proteins RNA and DNA recognition and binding surfaces are independent."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDDLLPEAFAVVREAATRVLGMRPYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLAQRDASEMGQLHEFLGLTVGINLNSMSREEKQEAYAADITYSTNNELGFDYLRDNMGLYKEECVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAFVRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQGLRAHVVMHRDTDYVVQEGEIVIVDQFTGRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIRDDRADLIFKSMEGKFNAVVEDIVNRHKKGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGIKGAVTIATNMAGRGTDIKLGDDVKNVGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSMEDELMRRFGSDNMKAMMDRLGMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDDVLRQQREVIYKQRQEVMESDNLRGIIEGMMKSTVERAVALHTQEEIEEDWNIKGLVDYLNTNLLQDGDVKEEELRRLAPEEMSEPIIEKLIERYNEKEKLMPEEQMREFEKVVVFRVVDTKWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMVASIEEEISRYIMKAEIEQNLERQEVVQGEAVHPSSDGEEAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIVQ",
    "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQDFLALTLQGEQPATREGKQANFSWRWLGEGLLECTPHAQYDKAVVLSAGVHGNETAPIELLSHLCTVLFAGRLKLAVRLLLVLGNPYAMRQGKRYVHDDVNRMFCGGYKNLPVTEESKRAEVLEQTVATFFQESSSQAKRYHYDLHTAIRASLLPTFALFPYQTHSYDADLTASLEAADLDALVYHNAVGKTFTHFTSENFKAASATLELGKALPFGQNDLSQFASIDEVIRNVVSEQALPVRNKPKIRVFQVSDSLIKRDEEFHMNLSAEAPNFSTFTKGEIIATQPSGNYVVEQDQVWILFPNPNVKIGLRAGLVLTETI",
    "output": "Transforms N(2)-succinylglutamate into succinate and glutamate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "QGYSTVAFDGPPSYGHAPSHHAAQFSNHSFKHEDPIAQQTSLGDQQYSVPPPVYGCHTPTDSCTGSQALLLRTPYNSDNLYQMTSQLECMTWNQMNLGSTLKGHATGYENENHTAPMLYSCGAQYRIHTHGVFRGIQDVRRVPGVAPTIVRSASETNEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGKTSEKPFSCRWPSCQKKFARSDELVRHHNMHQRNMTKLQLAL",
    "output": "Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKAVGLVVEYNPFHNGHRYHLAQAKRLTGADVVVAVMSGDFTQRGEPTILDKWSRTLAALQNGVDLVVELPVADAVQPAHRFAMGALSLLNDLQVADVVFGAEHPDWDFAAMVKAEQDFNQAAFHQFNNTYATQFNQQLEAVTGHALTDPNDILAFAYHRAKAAGDFGFHLQPIQRVDNHYADQQLTGAISSAGAIRQAVKGHQDVTETVPVQTASALAKLTTIPNWEQLYPLLANHLIQTPAPLLEQTYQVKEGLENRLKEAAERHRDFTSFLKAVKTKRYTYGRLMRVAFYLTLNLSDQDMANYHPYHRVLGFTAAGQAYLHQVKKELSYPLITKVNQRMKNAELALDYRAGKLYQFFGTPEQDLTRGPIRLV",
    "output": "Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTHQTHSYHMVNPSPWPLTGALSALLMTSGLIMWFHFNSMILLTLGLSTNILTMYQWWRDIIRESTFQGHHTPTVQKGLRYGMILFIVSEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRKHMLQALFITIALGLYFTLLQASEYYEAPFTISDGIYGSTFFVATGFHGLHVIIGSTFLIVCFLRQVKFHFTSNHHFGFERAAWYWHFVDVVWLFLYVSIYWWGS",
    "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASFPETDFQICLLCKEMCGSPAPLSSSSSASSSSSQTSTSSAGGGGPGAAARRLHVLPCLHAFCRPCLEAHRLPAPGGAGPAEALKLRCPVCDQKVVLAEAAGMDALPSSAFLLSNLLDAVVATADEPPPKNGRAGGGPGGAGGHSNHRHHAHHPAQRAAAPAPQPPPGPAASPGSLLLRRPHGCSSCDEGNAASSRCLDCQEHLCDNCVRAHQRVRLTKDHYIERGPPGPAAASAAQQLGLGPPFAGAPFSILSVFPERLGFCQHHDDEVLHLYCDTCSVPICRECTLGRHGGHSFAYLQDALQDSRALTIQLLADAQQGRQAIQLSIEQAQTVAEQVEMKAKVVQSEVKAVTARHKKALEERECELLWKVEKIRQVKAKSLYLQVEKLRQNLNKLESTISAVQQVLEEGRALDILLARDRMLAQVQELKTIRGLLQPQEDDRVMFTPPDQALYLALKSFGFVSSGAFAPLTKAAGDGIKRALQGKVASFTVMGYDHNGEPRLSGGDLMSVVVLGPDGNLFGAEVSDQQNGTYVVSYRPQLEGEHLVSVTLYNQHIENSPFKVVVKSGRSYVGIGLPVLSFGSEGDGEGKLCRPWGVSVDKEGYIIVADRSNNRIQVFKPCGSFHHKFGTLGSRPGQFDRPAGVACDASRRIVVADKDNHRIQIFTFEGQFLLKFGEKGTKNGQFNYPWDVAVNSEGKILVSDTRNHRIQLFGPDGVFLNKYGFEGSLWKHFDSPRGVAFNHEGHLVVTDFNNHRLLVIHPDCQSARFLGSEGTGNGQFLRPQGVAVDQEGRIIVADSRNHRVQMFEANGSFLCKFGAQGSGFGQMDRPSGIAVTPEGLIVVVDFGNNRILIF",
    "output": "E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance (By similarity). Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A (By similarity). In addition, participates in post-transcriptional mRNA repression in a miRNA independent mechanism (By similarity). Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1 (By similarity). Specific regulator of miRNA biogenesis. Binds to miRNA MIR29A hairpin and postranscriptionally modulates MIR29A levels, which indirectly regulates TET proteins expression (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSGAVLTSQEYITHHLSNLKVGEGFWAVHLDSLGWSVFLGLVFLTIFRSVAKKATSGVPGKLQCAVEMVVGFVDDSVKSTFHGKNALIAPLSLTIFVWILLMNSMDWVPVDLLPHLIHWVTGMPLGDIYMKPVPTADPNITFGLALGVFILIIYYSIKVKGVGGFMKELTTQPFGHWSLYPVNFILETVTMLARPLSLALRLFGNLYAGELIFLLIATIGVFQLPVHFLWAAFHLLVIPLQAFIFMMLTIVYLSLAHEDH",
    "output": "Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVNNMTDLTAQDAVWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWVKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHRDGLPAADFSVFYHLISIDRNRDIMLKVALSENDLHVPTFTKLFPNANWYERETWEMFGITFDGHPHLTRLLMPPTWEGHPLRKDYPARATEFDPFELTKAKQDLEMEALTFKPEDWGMQRGTENEDFMFLNLGPNHPSSHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDVVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLRDFLDWMPKRLDSYEKAALRNTILKGRSQGVAAYGKKEALDWGCTGAALRATGIDFDVRKSRPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMVEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPVAVRGSLVSDLIVHLGSIDFVMSDVDR",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTTFYTVVSWLVILGYWVLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLSVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAQENSSVASSLFKLCERRQGIAGVKGNQLQLLTDSDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQVAESLMAAARRGIHCRLMLDSAGSVAFFRSPWAAMMRNAGIEVVEALKVNLMRVFLRRMDLRQHRKMVMIDNYIAYTGSMNMVDPRFFKQDAGVGQWVDLMARMEGPVATAMGIVYSCDWEIETGKRILPPSPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTATYAAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSLLVGWASRAFFSELLAAGVKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLVIDDTGFGADLAAVQDDYISRSRLLDARLWVKRPLWQRITERLFYFFSPLL",
    "output": "Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKLILVLLCLISTLFVVKGGLSPTEQQIIVSYHNKWRSSPIGPTPSTTIPALKWNATIAAALQSSLDKCDGKFSTMSQYGTNSEWQSWWTPNTYFNLNATLDNIQKGASFYDWNAKGCNSSANYNCQLWTYAVWSKSTSYGCAKTICPDKSEVSCSYYPAGGFKGVLPYTPKTTTPAPTTPAPTTPKPTTPAPTTPKPTTPAPTTPKPTTPAPTTPKPTTPAPTTPKPTTPAPTTPAPTSTLTVDWTSYQTPIRDQGQCGSCWAFASSAALESRYLIKYGTAQKSTLQLSNQNAVNCIASGCNGGWSGNYFNFFKTPGIAYEKDDPYKAVTGTSCITTSSVARFKYTNYGYTEKTKAALLAELKKGPVTIAVYVDSAFQNYKSGIYNSATKYTGINHLVLLVGYDQATDAYKIKNSWGSWWGESGYMRITASNDNLAIFAYNSYYPTF",
    "output": "Thiol protease that seems to be involved in the sexual development."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPKYKTSEQVLSLMKDRTRVRNIGIIAHVDHGKTTTSDQLLAASGIISPKVAGEALALDYLSVEQQRGITVKAANVSLYHEVEGKGYVINLIDTPGHVDFSGRVTRSLRVLDGSIVVVDSVEGVMTQTETVLRQSLEERVRPILFVNKVDRLVKELKLGPQEMMQKLMDIIKEVNNLINIYAEPELKEKWAINPTLGNVVFGSAKDRWGFSIPMAQKKGINMKHVIDAYSTTDKTKINELASQVPINEALLDAVIKFVPNPVDAQKYRIPKIWKGDLDNELAKSMLNADPNGPVVMMITDMKVDPHAGLVATGRVFSGTIRPGSEVWLVNAKAPQKVLQVSIYMGQFRELADEIPAGNIAAVLGLERARSGETLIDIRYKDLQGSFEKLHYVSEPVVTIAVEPKNPKDLTKMIDALRKLSIEDPNLVVKINEETGEYLLSGMGFLHVEVSLQLLKDNYGVDVVTTPPIVVYRESVRNKSQVFEGKSPNKHNKFYISVEPLNDKTIELISNGTIKEDMDSKEMAKILRDQADWDYDEAKKIIAIDENVNVLIDATSGVQHLREIMDTMLQGYRLAMREGPLAHEPIRGVKVILHDATIHEDPAHRGPAQIYPAVRNAIFAAMLMSKPTLLEPLQKLDIRVPMEFVGNVTAVLSRKRGKVLNMTQSGSVARILAEIPVSESYELASDLRGSTGGRAFWGTEFSKWAPVPDSILTDVILKIRERKGLPKELPKVEDFLS",
    "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARDYYGILGVDRNATDSEIKKAYRKLARKYHPDVNPSEEAAEKFREASVAHEVLTDPDKRRIVDMGGDPMEQGGGAGHPGGFGSGGLGDIFDAFFGGGAGSRGPRSRVQPGSDTLWRTSITLEEAFTGVKKDLTLDTAVLCSKCHGSGSASNAKPKTCGTCHGSGEIQEVQRSFLGNVMTSRPCHTCNGTGEVIPDPCDECAGDGRVRARRDIVADIPAGIQSGMRIRMAGQGEVGAGGGPAGDLYVEVMVRPHAVFTRDGDDLHASIRVPMIDAALGSELEVESLTGEEITVVIPAGTQPNQVITLEGEGMPRLRAEGRGDLMAHVDLFVPTEIDDRTRELLEQIRDYRRDNSSVHREGEEHGGLFDKLKSKFRNR",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MATQAAPASGVRNGAGPEWGGFEENIQGGGSAVIDMENMDDTSGSSFEDMGELHQRLREEEVDADAAAAEEEDGEFLGMKGFKGQLSRQVADQMWQAGKRQASKAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKMVNFPQKVAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHLHALFYLFWLLLGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLEGPNIPPMQRVPRDIPAVLPAAKLPVAVVNATAKAIAVTLQSH",
    "output": "Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGVFTYETEFTSVIPPPRLFKAFILDADNLIPKIAPQAVKCAEIIEGDGGVGTIKKITFGEGSQFGSVTHKIDGIDKDNFVYSYSLVEGDALSDKIEKISYETKLVASSDGGSIIKSTSNYHTKGDVEIKEEHVKAGKEKASHLFKLVEGYLLANPNEYC",
    "output": "Possesses ribonuclease activity in vitro."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGCRACLRPEASGAVQGRWLGAALSGLCLLSALALLEWLGAPTETAWRAAQGNVDAPNVGSSTAQVPRLLTMSVTRRRRYTLTPARLRWDHFNLTYRVLSFPRNLLSPEETRRGLAAAFRMWSDVSPFSFREVAPERPSDLKIGFYPVNHTDCLVSAVHHCFDGPTGELAHAFFPPHGGIHFDDSEYWVLGPTRYSWKKGVWLTNLVHVAAHEIGHALGLMHSQQDQALMHLNATLRGWKALSQDELWGLHRLYGCLDRIFVCASWARKGFCDVRQRLMKRLCPRSCDFCYEFPFPTVATTTSPTRTKTRLVREGRNMTFHCGQKILHKKGKVYWYKDQEPLEFSYPGYLALGEAQLSIIANAVNEGTYTCVVRRHQRVLSTYSWRVRVRN",
    "output": "Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEEQVNIKKKEKWGIAHIYSSFNNTIIHITDITGAETISRWSGGMVVKADRDEPSPYAAMLAARRAAEEALEKGIVGVHIRVRAPGGSKSKTPGPGAQAAIRALARAGLKIGRVEDVTPIPHDGTRPKGGRRGRRV",
    "output": "Located on the platform of the 30S subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPRPTGKKFDKRRQQQNPLFKRKKFCRFTAAGVEQIDYKDIDTLKDFIGENGKITPARLTGTKAHYQRQLDTAIKRARFLALMPYTDQHKA",
    "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEVVEVLHMNGGNGDSSYANNSLVQQKVILMTKPITEQAMIDLYSSLFPETLCIADLGCSLGANTFLVVSQLVKIVEKERKKHGFKSPEFYFHFNDLPGNDFNTLFQSLGAFQEDLRKHIGESFGPCFFSGVPGSFYTRLFPSKSLHFVYSSYSLMWLSQVPNGIENNKGNIYMARTSPLSVIKAYYKQYEIDFSNFLKYRSEELMKGGKMVLTLLGRESEDPTSKECCYIWELLAMALNKLVEEGLIKEEKVDAFNIPQYTPSPAEVKYIVEKEGSFTINRLETSRVHWNASNNEKNGGYNVSRCMRAVAEPLLVSHFDKELMDLVFHKYEEIVSDCMSKENTEFINVIISLTKIN",
    "output": "Converts benzoic acid into the volatile ester methyl benzoates . This scent, mostly produced in a rhythmical, diurnal manner, attracts the pollinators ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIGLGGGYLLLQMINRIALPAGLYPLLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDNQLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLKIGVRVAEEEAES",
    "output": "K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK",
    "output": "Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKFIQHIGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFNDWRFLDDAGKVPNPDFVLNLPRYQGATILLARENFGCGSSREHAPWALTDFGFKVVIAPSFADIFYGNAFNNQLLPVTLSEADIDTLFQLVKENEGIEFVVDLEQQTVNAGGKSYAFEIDPFRRHCMINGLDSIGLTLQHEHNISAYEKQQPEFLR",
    "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI",
    "output": "Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKRNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGINYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYSTENIPGCSSSGSCSQGSGILHYTHGDSQQTHLLKQGRSSMGTGLSGGKRPSQEEDTQSIGPKVQRQSTN",
    "output": "Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers'). The predominant Zeitgeber for the central clock is light, which is sensed by retina and signals directly to the SCN. The central clock entrains the peripheral clocks through neuronal and hormonal signals, body temperature and feeding-related cues, aligning all clocks with the external light/dark cycle. Circadian rhythms allow an organism to achieve temporal homeostasis with its environment at the molecular level by regulating gene expression to create a peak of protein expression once every 24 hours to control when a particular physiological process is most active with respect to the solar day. Transcription and translation of core clock components (CLOCK, NPAS2, BMAL1, BMAL2, PER1, PER2, PER3, CRY1 and CRY2) plays a critical role in rhythm generation, whereas delays imposed by post-translational modifications (PTMs) are important for determining the period (tau) of the rhythms (tau refers to the period of a rhythm and is the length, in time, of one complete cycle). A diurnal rhythm is synchronized with the day/night cycle, while the ultradian and infradian rhythms have a period shorter and longer than 24 hours, respectively. Disruptions in the circadian rhythms contribute to the pathology of cardiovascular diseases, cancer, metabolic syndromes and aging. A transcription/translation feedback loop (TTFL) forms the core of the molecular circadian clock mechanism. Transcription factors, CLOCK or NPAS2 and BMAL1 or BMAL2, form the positive limb of the feedback loop, act in the form of a heterodimer and activate the transcription of core clock genes and clock-controlled genes (involved in key metabolic processes), harboring E-box elements (5'-CACGTG-3') within their promoters. The core clock genes: PER1/2/3 and CRY1/2 which are transcriptional repressors form the negative limb of the feedback loop and interact with the CLOCK|NPAS2-BMAL1|BMAL2 heterodimer inhibiting its activity and thereby negatively regulating their own expression. This heterodimer also activates nuclear receptors NR1D1/2 and RORA/B/G, which form a second feedback loop and which activate and repress BMAL1 transcription, respectively. CRY1 and CRY2 have redundant functions but also differential and selective contributions at least in defining the pace of the SCN circadian clock and its circadian transcriptional outputs. More potent transcriptional repressor in cerebellum and liver than CRY2, though more effective in lengthening the period of the SCN oscillator. On its side, CRY2 seems to play a critical role in tuning SCN circadian period by opposing the action of CRY1. With CRY2, is dispensable for circadian rhythm generation but necessary for the development of intercellular networks for rhythm synchrony. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. Interacts with CLOCK-BMAL1 independently of PER proteins and is found at CLOCK-BMAL1-bound sites, suggesting that CRY may act as a molecular gatekeeper to maintainCLOCK-BMAL1 in a poised and repressed state until the proper time for transcriptional activation. Represses the CLOCK-BMAL1 induced transcription of BHLHE40/DEC1, ATF4, MTA1, KLF10 and NAMPT. May repress circadian target genes expression in collaboration with HDAC1 and HDAC2 through histone deacetylation. Mediates the clock-control activation of ATR and modulates ATR-mediated DNA damage checkpoint. In liver, mediates circadian regulation of cAMP signaling and gluconeogenesis by binding to membrane-coupled G proteins and blocking glucagon-mediated increases in intracellular cAMP concentrations and CREB1 phosphorylation. Inhibits hepatic gluconeogenesis by decreasing nuclear FOXO1 levels that down-regulates gluconeogenic gene expression. Besides its role in the maintenance of the circadian clock, is also involved in the regulation of other processes. Represses glucocorticoid receptor NR3C1/GR-induced transcriptional activity by binding to glucocorticoid response elements (GREs). Plays a key role in glucose and lipid metabolism modulation, in part, through the transcriptional regulation of genes involved in these pathways, such as LEP or ACSL4 (By similarity). Represses PPARD and its target genes in the skeletal muscle and limits exercise capacity (By similarity). Plays an essential role in the generation of circadian rhythms in the retina (By similarity). Represses the transcriptional activity of NR1I2 (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTTQQIVLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCADNMTLTVSRSEQKIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPSTRVITNQYNSPTGLYSSENISNFNNAVESKTSASGEEANSRPVVQPHPSGSLIIDKDSEVYKMLQEKQELNEPPKQSTSFLVLQEILESDGKGDPNKPSGFRSVKAPVTKVAASVGNAQKLPICDKCGTGIVGVFVKLRDHHRHPECYVCTDCGINLKQKGHFFVEDQIYCEKHARERVTPPEGYDVVTVFRE",
    "output": "Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (By similarity). Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY",
    "output": "May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKKITAYIKLQVKAAQANPSPPVGPALGQHGVNIMEFCKAFNARTQGIEPGLPTPVIITVYSDRSFTFETKSTPASVLLKKAAGLTSGSAHPNTVKVGTVTRAQLEDIAKAKNADLTAADMEAAVRTIAGSARSMGLNVEGV",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSYKSGFVSIVGRPNVGKSTLLNQVVGTKIAIMSDKPQTTRNKIRAVLTSEKGQIIFIDTPGVQKPRNKLGEFMLKQALTSLDEVDVLLYVVEANSPIGPQENYLLKTLAEVKTPIILVVNKIDVVKMIEAQTLARQIESRLKVAKTYYISALNGTGVSELVEGIFELLPEGPPYYPEGQVTDYPERFIIAEYIREQILHLTREEIPHSVAVVVEEIKPRENSNTVYVSAVIYVERESQKGIIIGKNGQMLKEIGQRARLEIERLLGSNIYLDLWVKVKEDWRNKDVWIRNFGFTEFE",
    "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "PFNPETVYALLAMLISFFVLLASARKENSDEGISFNFTNFTRGDQGVTLLGQANIMANGILALTNHTNPTWNTGRALYSKPVPIWDSATGNVASFVTSFSFVVQEIKGAIPADGIVFFLAPEARIPDNSAGGQLGIVNANKAYNPFVGVEFDTYSNNWDPKSAHIGIDASSLISLRTVKWNKVSGSLVKVSIIYDSLSKTLSVVVTHENGQISTIAQVVDLKAVLGEKVRVGFTAATTTGRELYDIHAWSFTSTLVTATSSTSKNMNIASYA",
    "output": "Bark lectins are storage proteins that probably maintain stocks of nitrogen during dormant period. Self-aggregatable molecules that can bind their own carbohydrate side chains. They could also play a role in the plant's defense against phytophagous invertebrates or herbivorous higher animals."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVSSRKELRCPECRTLVECGVDELPSNILLVRLLDGIRQRPRKAGDGGSAGNSTNALRAQGSVTTNGGLNDAQNTQSGQQRIQARSPPVRGVPQLPCAKALYNYEGKEPGDLKFNKGDIIVLRRQVDENWYHGEINGIHGFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFLKDDILTVIRRVDENWAEGMLGDKIGIFPISYVEFNSAAKQLIELDKPSGADTGEGSSGTSHSGNSQKQADAKKNTKKRHSFTSLTMSNKSSQSVQNRHSMEISPPVLISSSNPTAAARISELTGLSCSAPSQDMNPPLLPPPPMATPVITSASSGAAAVAQRNIIGPVEQVPHLRTSARPSVFIAIYPYIPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVAPVTRALTTATPAKVAMATATTSNVVNLVTPTPPGAPCQKLPVSGVEFAKTSSTNGVSPAGVPGCHIQTSPQSKVLLHMSGQMTVNQARNAVRTAAAHSQDRPTAAVTPIQAQTPAASALPQQAAASQQVPPPLSAPAAYINAAMNISRPSVPAASAASSALPTAAFEAESSWKSSSGLSGCSFSENVSAPLNSAANKQDKDSKKEKKGLLKLLSGASTKRKPRSSPPHSPTQEVEQTNSEAAAALEGAVGPDIVPVIVNGRAAPCTVDCDSVSASTPAQDNRKPASLDNNIPIAPPPRQPCSSLGSVLNDSRPCERYRVMVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI",
    "output": "Has E3 ubiquitin-protein ligase activity. In the absence of an external substrate, it can catalyze self-ubiquitination. Acts as a scaffold protein that contributes to the effective activation of the JNK signaling pathway (By similarity). Plays an essential role in the anterior neural development."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGGKWSKSSVIGWPTVRERMRRAEPAADGVGAASQDLEKHGAITSSNTAATNADCAWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCYKLVPVEPEKLEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC",
    "output": "Factor of infectivity and pathogenicity, required for optimal virus replication. Alters numerous pathways of T-lymphocyte function and down-regulates immunity surface molecules in order to evade host defense and increase viral infectivity. Alters the functionality of other immunity cells, like dendritic cells, monocytes/macrophages and NK cells.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADQEFDIDAYFASQSEGKSVVASTPENQHCGFVAIVGRPNVGKSTLLNNLLGQKISITSRKPQTTRHRIMGVETDGNYQAIYVDTPGLHIEEKRAINRLMNRAASSSLSDVNLVLFVVEGTHWTADDEMVFTKLQKANFPVVLCVNKVDQVKDRNEVMLHMLELSKRMQFVDIVPISAKQGKNTDVLKKHVRDHLPKAVHHFPEEYVTDRSQRFMASEIVREKLMRFTGEELPYSVTVEIERFDYNPDTDGFHINALILVERIGQKKMVIGKNGEKIKTIGREARLDMEELFGRKVYLETWVKVKSGWADDERALRSLGYIDDL",
    "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKQAIESFIQSKKVSVNSQKSYTYDLQQFVTVTKGEISQQSLLVYQQSLLDLKPAAQKRKMSAVNQFLYFLYENNLLDRFYKLQTTSGPASVKKKLEREDLTLLFQESPWLEGQLIALLIAYLGLTPSEIAELTSQQVNLDFQVLTVEKGGAKRVLTLPKELIPYMESHLSGRYVFDKKGQTYSRQWFFNRLTEFVQSIGKPDWTAQKLREQYILKQIDEGKSLDQIAKQLGLKTSMSLEKFR",
    "output": "Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNPQLHNIILPIYMDYQATTPLDPRVMEAMLPYFTTKFGNPHSRSHSFGWEAENAVEEARSRVAKLIGADAKEIIFTSGATESNNLAIKGIAKFYGNKKNHIITVVSEHKCVLDACRHLEQEGIKITYLPINPNGIIDLEILKESITNQTMLVSVMAVNNEIGVIQPLKEIGKICRERGVFLHSDIAQGFGKIPINVNEFNIDLASISGHKIYGPKGVGALYVRKKPRIRVTPLINGGGQERGMRSGTLPTPLIVGLGMAAEIAYNEMEKDNKHVSYLFDRFLNNIKQKISEVYLNGDKDQRYKGNLNLSFAGVEGESIILAIKDLAVSSGSACTSASLEPSYVLRSMGIGEELAHTSIRFGIGKFTTEQEIDYAVDLICSKIDKLRELSPLWEMMQQGIDLKKIKWASH",
    "output": "Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSLRHFLTLSDFTKQELENLIKRASELRKMQHAGEIYQPFVGRTLGMIFEKSSTRTRISFETGMGQFGGNAIFLSPNDTQLGRGEPLEDSARVISSMVDIIMIRTFGHEKVETFAKYSSVPIINALTDEFHPCQLLADMQTYYEHRGSIENKIVTWVGDGNNMCASFMQAAHQFGFELRVAAPYGFEPDSALMERFSHCVSLVENVQDAAKDSNLIVTDVWASMGQESEQNTRARRFAPYQVTPSLLDKADPEVVFMHCLPAHRGEEISHDMLDDPRSVVWDEAENRLHAQKALMEFLLKDKIKLPA",
    "output": "Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADAETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDGQPELFIHIIPDKTNNTLTIIDSGIGMTKADLVNNLGTIARSGTKEFMEALAAGADVSMIGQFGVGFYSAYLVADKVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGEALGRGTKMVLYLKEDQMEYIEERRLKDLVKKHSEFISYPISLWIEKTIEKEISDDEEEEEKKDEEGKVEEVDEEKEKEEKKKKKIKEVSHEWDLVNKQKPIWMRKPEEINKEEYAAFYKSLSNDWEEHLAVKHFSVEGQLEFKAILFVPKRAPFDLFDTKKKPNNIKLYVRRVFIMDNCEDIIPEYLGFVKGIVDSEDLPLNISRETLQQNKILKVIRKNLVKKCLELFFEIAENKEDYNKFYEAFSKNLKLGIHEDSQNRTKIAELLRYHSTKSGDELTSLKDYVTRMKEGQNDIFYITGESKKAVENSPFLEKLKKKGIEVLYMVDAIDEYAIGQLKEFEGKKLVSATKEGLKLDETEDEKKKKEELKEKFEGLCKVIKDVLGDKVEKVIVSDRVVDSPCCLVTGEYGWTANMERIMKAQALRDSSMGGYMSSKKTMEINPENSIMDELRKRADADKNDKSVKDLVLLLFETALLTSGFSLDEPNTFGSRIHRMLKLGLSIDDDDVVEADADMPPLEDDADAEGSKMEEVD",
    "output": "Functions as a holding molecular chaperone (holdase) which stabilizes unfolding protein intermediates and rapidly releases them in an active form once stress has abated. Functions as a folding molecular chaperone (foldase) that assists the non-covalent folding of proteins in an ATP-dependent manner . Regulates RPP4-mediated temperature-dependent cell death and defense responses . May assist SGT1B in the formation of SCF E3 ubiquitin ligase complexes that target the immune receptors SNC1, RPS2 and RPS4 for degradation, to regulate receptor levels and avoid autoimmunity ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "SCSCKRNFLCC",
    "output": "Potential neurotoxin. No target has been identified for this peptide."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLKRIVQAFFIIFGGVVGIFLIPELFVLLNIQDIPLITNAYTSAAIGAIIFFLISIWGTEYVVNWVKWIEDSLLKAPVPDLLFGSLGLVFGLIIAYLIVNVIPLDNIPYRIFSTIIPVFLAFFLGYLGFQVGFKKKDELISLFSISARMQKKKGTADEEHEVQDKKLKILDTSVIIDGRIADICQTGFLEGVIVIPQFVLEELQHIADSSDVLKRNRGRRGLDILNRIQKELDIEVEIYEGDFEDIQEVDSKLVKLAKLTSGVVVTNDFNLNKVCELQKVAVLNINDLANAVKPVVLPGEEMNVQVIKDGKEHNQGVAYLDDGTMIVVEEGRNYIGKHIDVLVTSVLQTAAGRMIFAKPKLLEKAL",
    "output": "An RNase."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVPQTETKAGAGFKAGVKDYRLTYYTPDYVVRDTDILAAFRMTPQLGVPPEECGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVPGEDNQYIAYVAYPIDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFVGPPHGIQVERDKLNKYGRGLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEAIYKAQAETGEVKGHYLNATAGTCEEMMKRAVCAKELGVPIIMHDYLTGGFTANTSLAIYCRDNGLLLHIHRAMHAVIDRQRNHGIHFRVLAKALRMSGGDHLHSGTVVGKLEGEREVTLGFVDLMRDDYVEKDRSRGIYFTQDWCSMPGVMPVASGGIHVWHMPALVEIFGDDACLQFGGGTLGHPWGNAPGAAANRVALEACTQARNEGRDLAREGGDVIRSACKWSPELAAACEVWKEIKFEFDTIDKL",
    "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNIIIMIIIAYLLGSIQTGLWIGKYFYQVNLRQHGSGNTGTTNTFRILGVKAGIVTLTIDILKGTLATLIPIILGITTVSPFFIGFFAIIGHTFPIFAQFKGGKAVATSAGVLLGFAPSFFLYLLVIFLLTLYLFSMISLSSITVAVVGILSVLIFPLVGFILTDYDWIFTTVVILMALTIIIRHQDNIKRIRKRQENLVPFGLNLSKQKNK",
    "output": "Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLQPKRTKFRKVHKGRNRGLAQGTDVSFGTFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM",
    "output": "Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTCPICGSKTAPSYRPFCSKRCADLDLAKWLNGSYAIPASSEDEEEPLDQEAETPVAPRH",
    "output": "Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MHKLKLHGFNNLTKSLSFCIYDICYTKTADDRDGYIAYIDEQYNANRLTEILTETCSIIGANVLNIARQDYDPQGASVTILVSEEPIDPRDVDTSEHPGPLPNSVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDINGVKHFIDHQINSVQNFMSEDMKSLYHMMDVNVYQENIFHTKMLLKDFDLKHYLFNVNPEELSAAERKRITDLLYHEMQEIYYGRNLPVL",
    "output": "Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVAALLGGGGEARGGTVPGAWLCLMALLQLLGSAPRGSGLAHGRRLICWQALLQCQGEPECSYAYNQYAEACAPVLAQHGGGDAPGAAAAAFPASAASFSSRWRCPSHCISALIQLNHTRRGPALEDCDCAQDENCKSTKRAIEPCLPRTSGGGAGGPGAGGVMGCTEARRRCDRDSRCNLALSRYLTYCGKVFNGLRCTDECRTVIEDMLAMPKAALLNDCVCDGLERPICESVKENMARLCFGAELGNGPGSSGSDGGLDDYYDEDYDDEQRTGGAGGEQPLDDDDGVPHPPRPGSGAAASGGRGDLPYGPGRRSSGGGGRLAPRGAWTPLASILLLLLGPLF",
    "output": "Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLTDTLIQEFQDRNLISQITNEIDLKNILLHNKISLYCGFDITADSLHVGHILPLLCLRRFQNLGHRPVILMGGGTSLIGDPSFKLLERQLNSIELVHTWKQKITKQLSLFLKFNVGKNNALIVDNYEWFKNINVLTFLRDIGKHFSINQMIVRDAIQRRIKRLDQGISFTEFSYNLLQAYDFYFLNKQLDVILQIGGSDQWGNIISGIDLIRRLHKKRAYGITVPLLTKKDGRKFGKTELDTIWLDKMKTSPYKFYQYWMNISDSDIYSFLKMFTFLSLSEIKALKDTTKPTELNSVKKILAEYLTNLVHGSNEVRAIQRITSSLFSGKFSEMKETDFFQLEQDGMPSVQLYNSGNLQQLLVYSRLALSRSHAKSMIVSNSVRINNIIQNNPFYILCNRDKMYHKYTLLSRGKKNFCLLCWTK",
    "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLQPKRTKFRKVHTGRNRGLAKGTEVSFGSFGLKAVGRGRLTARQIEAARRAMTRHIKRQGKIWIRVFPDKPITEKPLEVRQGKGKGNVEYWVAQIQPGKVMYEVDGVPEELAREAFRLAARKLPFKTTFVTKQVM",
    "output": "Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIKLTRRQIIRRTAGTLFALSPIASAVAKTVRAPQFTAARIWPSHTYTRLTLESTAALKYQHFTLDNPGRLVVDIQNANINTVLHGLSQKVMADDPFIRSIRAGQNTPTTVRLVIDLKQPTHAQVFALPPVGGFKNRLVVDLYPHGMDADDPMMALLNGSLNKTLRGSPEADLAQNTTPQPGRGRNGRRPVIMLDPGHGGEDPGAISPGGLQEKHVVLSIARETKNQLEALGYNVFMTRNEDVFIPLGVRVAKGRARRADVFVSIHADAFTSPSARGTGVYMLNTKGATSSAAKFLEQTQNNADAVGGVPTSGNRNVDTALLDMTQTATLRDSRKLGKLVLEELGRLNHLHKGRVDEANFAVLRAPDMPSILVETAFLSNPAEEKLLGSESFRRQCAQSIASGVQRYINTSVLKRG",
    "output": "Cell-wall hydrolase involved in septum cleavage during cell division."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAEGQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVLDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKMHYRKKKQILRLRKQAEKNVEKKICKFTEVLKTNGLLV",
    "output": "Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions . Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes . Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation (By similarity). In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex (By similarity). Involved in methylation of rRNA (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRHSVLSISFAVALFLECYTPSTAIPIGKMDDVALEQDTLDSLLRVEVSENSPDSVRGRSSKIVLLADSGLWMNLNRGLPFYKLRAAAAGPDRALTLDRQEAGQDLSPSISIVRRDTMRCMVGRVYRPCWEV",
    "output": "Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGKDTIADIITSIRNADMNRKGTVRIASTNITENVVKILLREGFIENARKLVENKNKKEFLVLTLRHRRNRKGPYRPILNLKRISRPGLRIYFNYRRIPRILDGMGIVILSTSRGIMTDRAARLERIGGEILCYIW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTASPDYLVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKVGQLHEVLVRPDQLELTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHIRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVAAMTESLNFEKSDSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCKMELIDDSTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYTFPAPTAVIPTEAAIYQPSLLLNPRALQPSTAYYPAGTQLFMNYTAYYPSPPGSPNSLGYFPTAANLSSVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYATEDGLVHTNDQARTLPKEWVCI",
    "output": "mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity). Regulates splicing and expression of genes involved in inner ear development, auditory hair cell differentiation, and cell fate specification in the cochlear epithelium ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSRRYFGTDGIRGRANGLITPELALKVGQAAGLVFQRGDHRHRVVIGKDTRLSGYMIENAMVAGFTSVGMDVLLVGPMPTPAVAMLTKSMRADLGVMISASHNMFEDNGIKLFGPLGFKLSDDVEKQIEQLLDEPMDKKLSESASLGRARRIDGVHDRYIEFAKRTLPRDLSLDGLRVVVDCANGAAYKVVPEALWELGADVISIGVEPDGFNINKECGSTSPEALCRKVREMRADIGIALDGDADRVIMVDERGHVIDGDQLLAVIAQSWKEDGRLARPGIVATVMSNLGLERFLASEGIELVRTSVGDRYVLEAMLRDGYNVGGEASGHIILSDYATTGDGFVAALQILAVVQKLGRPVSEVCHRFDPLPQILKNVRYRAGRPLDDAGVQSAISDAEKRLNGHGRLLIRPSGTEPVIRVMGEGEDRIMVEEVVDTIVDALGNASAAAA",
    "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSRYLFTSESVTEGHPDKICDQISDTIIDAILAQDPQSRVAAEVVVNTGLVLITGEITTKAQVNYIELARKKIADIGYVHAENGFSADSCSVLVALDEQSADIAQGVDKAQETRELLSEEELDAVGAGDQGLMFGFACNETPELMPLPISLAHRVCRQLTAVRKTGQLPYLRPDGKSQVTITYEDGRPVGIDTILISTQHTAKIGEITELSDIQAKIKEDLWKYVVEPIFKDAEIKPNSQTRFLVNPTGKFVIGGPQGDCGLTGRKIIIDTYGGYSRHGGGAFSGKDPTKVDRSAAYACRYIAKNIVAADLAEKCEVQISYAIGVAKPVSMMIETFGTSKVDEDKLLEVVKENFELRPAGIIQNFNLRNLPGERGGRFYQDVAAYGHLGRTDLDLPWEQTDKVELLKQAFSPQLLATAS",
    "output": "Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRHKRSTRRKRASATQLYQTCKASGTCPPDVIPKVEGTTIADQILRYGSLGVFFGGLGIGTGSGTGGRTGYVPLGSTPPSEAIPLQPIRPPVTVDTVGPLDSSIVSLIEESSFIDAGAPAPSIPTPSGFDITTSADTTPAILNVSSIGESSIQTVSTHLNPSFTEPSVLRPPAPAEASGHLIFSSPTVSTHSYENIPMDTFVISTDSGNVTSSTPIPGSRPVARLGLYSRNTQQVKVVDPAFLTSPHRLVTYDNPAFEGFNPEDTLQFQHSDISPAPDPDFLDIVALHRPALTSRRGTVRYSRVGQKATLRTRSGKQIGAKVHYYQDLSPIQPVQEQVQQQQQFELQSLNTSVSPYSINDGLYDIYADDADTIHDFQSPLHSHTSFATTRTSNVSIPLNTGFDTPLVSLEPGPDIASSVTSMSSPFIPISPLTPFNTIIVDGADFMLHPSYFILRRRRKRFPYFFADVRVAA",
    "output": "Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers. Plays a role in capsid stabilization through interaction with the major capsid protein L1. Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network. Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network. Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus. Mediates the viral genome import into the nucleus through binding to host importins. Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection. Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions. During virion assembly, encapsidates the genome by direct interaction with the viral DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVCGIYEEPVTPGQCNMVVERLGDYLLEQGL",
    "output": "Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNNKVNTRDFIVVKGARENNLKNVDIDIPKNKFVVMTGLSGSGKSSLAFDTIYAEGQRRYLESLSSYARQFLGGNEKPDVDSIEGLSPAISIDQKTTSHNPRSTVGTVTEIYDYLRLLFSRIGKPYCPNGHGLISTLSIKQMIDTVYENKEESKIQILSPIISQEKGTFKNKIEELKRQGYLRLRIDGNIYSLDDEIELEKTKKHNIDILIDRIILNNDTVTRSRIYDAIEKSVKEANGKVIVLVDDKELFFSQNHACNECGFSIPELEPRFFSFNSPVGACKSCNGIGFNFLPDTAKIVPDPSLSIKEGAIAYFRSVMMTPTMDLKREMSVWKEHDINLDVPFKELSKKEKNIIFYGDEDIGELKIDVNEQSIYSSSSFLYNNGLVNLIMRRFSETQSERAREYYEKFMSNLSCPSCNGQKLSIEALSVKINNKNIIDLTEKNINDLTNFFIELELNETDRNIAHLALKEIVDRLSFLENVGLNYLTLSRSASTLSGGESQRIRLATQIGSSLTGVLYVLDEPSIGLHQKDNEKLIETLKKMRDLGNTLIVVEHDEDTIRASDYLIDIGPKAGDFGGEVVAAGTVSEVSENKKSITAQYLSGKLKIEVPSKRRHGNGKTIELVGASGNNLKNVTVSFPLNKLIAVTGVSGSGKSTLINETLIKGIEKKLTNPFIVPAPFKDIKGLKNVDKIIKVSQDPIGRTPRSNPATYVSVFDDIRDLFANTKEAKARGFQKGRFSFNVSGGRCENCSGDGLIKIEMHFLPDVFVKCESCNGKKYNQETLQVLYKGKSIYDVLEMSVVEARDFFYEIPEIKRKLDLMVEVGIDYLKLGTSSTHLSGGEAQRIKLAKYLQKRATGKTIYVLDEPTTGLHIHDIAKLITVLNRIVDNGDTVIVVEHNLDLIKCADYVIDLGPDGGINGGQLVAYGTPEEIIEKKAVSYTGLFLEKNMYKDK",
    "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRSPRVIHLACVIAYIVAVEAGDKPVYLPRPTPPRPIHPRLAREVGWELEGQGLSPLSEAELLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSVAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRVASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEEEVLPEVRERGSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSVAEDLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDATLESELSPSSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEVLPEVRERRSPVDKGGYLPRPTPPRPVYRSRRDASLESELSPLSEAEGLPEVRERRSPGGQGGYLPRPTPRTPLCRSRRDANLDAEQSPVSEGVVLPEVR",
    "output": "Has antibacterial activity in vitro."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRSKFKDEHPFEKRKAEAERIRQKYADRIPVICEKVEKSDIATIDKKKYLVPSDLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYITYSGENTFGNFETA",
    "output": "Ubiquitin-like modifier involved in autophagosomes formation. With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIALATGPRYRVPFRRRREGKTNYYKRRELIKADAPRLVARKTLNHNIAQIVDFAPHGDVTLASAHSIELRNKFGWKGHCGNTPAAYLTGYLCGLRALERGIERAVIDIGLHRPVRGSRVFAMLKGALDAGMDIPHGEEVLPPEDRIRGEHIANLARQIKEEDPEEYERRFSKYLERGLKPEELPEHFEEVKSKIEEEFGGA",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTDRNEFLNDINKIVIKIGTSSLTKQNCDSTKENCSIDPTFIENIAAQVSELRKLGKEVIVVSSGAIGVGLYELGIAPKPREIPIRQAAAAVGQSILMQYWSEAFSKHGIKVAQILLTYEFYSDRVSYLNLRNSISTLLEYGVVPIINENDCTCTNEIEAIFGDNDKLSAMVASKIDADLLIILSDIDGLFDKNPKIHEDARLISLVEKITPEIESYGGDPTSFKGVGGMRTKIKAAKICSMAGCYVLIANSEIEDVLLKVLSGKEIGTLFLAERHIQKNRARWIILSRASGTIRVDAGAKAAVLGKNSLLSAGVVDVEGNFDRGDVVRLECEGRVFAKGITDYTSEELMKIKGAHTDEIEGILGYNNYSNVIKKENIGIMEN",
    "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGIEGVLERGVVTTTADKLINWARTGSLWPMTFGLACCAVEMMHAGASRYDMDRFGVIFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMSEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGIIQLQNKIKRNYTIAR",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIKLVLLRHGESQWNRENRFTGWYDIGLSEKGETESRAAGELLKKEGFTFDVAFTSVLKRAIGTLWNVLEGMDLMWIPVFKNWRLNERHYGALQGMNKAETAQQHGDEQVLVWRRSYDTPPPPLEKNDPRFPGNDPRYATLAPEEVPVTECLKDTVDRFLPLWNDEIAPMIRSGKRVIIAAHGNSLRALVKYLDNISEEDIVGLNIPTGVPLVYELDDDLKPLKSYYLGDQEELQKAIDSVANQGKA",
    "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKYNQYAYVETDFQQQVKELIDINFLPKNYQVWDFSSLLAKLVKNAIAEAKTDAAKNAKLAEFAVSDHQTLADFLKEKPTEIGTKQFYNVALQLLGYHVHYDYDFADPTGFMQRNALPFLQDISDNQKLISAFYRLLNTRAKNGQILLDVMAGKGYFTQFWGQNKFKFFNGKSIPVFDTNKVIREVVYVETDLDTDHDGKSDLIQVTVFRPEETNKGLKVPALYTASPYFGGIIANEKRNHNVDENLSDSTEWNDPQYVHSPIVKAEKPDGSSRPATEEAVHKSSYPLNEYMLARGFASVFAGAIGTRGSDGVRITGAPEETESAAAVIEWLHGDRVAYTDRTRTVQTTADWCNGNIGMTGRSYLGTLQIAIATTGVKGLKTVVSEAAISSWYDYYREHGLVIAPEACQGEDLDLLAETCQSNLWDAGSYLKIKPEYDKMQKQLREKEDRNTGQYSDFWEARNYRHHADGIKCSWISVHGLNDWNVKPKNVYKIWQLVKKMPMKHHLFLHQGPHYNMNNLVSIDFTDLMNLWFVHELLGIENNAYNQWPTVMIQDNLQADKWHEEPDWSNDLGQEKIYYPTDEGELFQDGNGKAQKSFTDVGGIEFKKAGISESDWQYKFICGDEKWAKPSLRFETDEFTHPTTIVGRPEVKVRVSASLPKGEISVALVELGERQRLTATPKFLMHGGQELGYRFGTDTLQEFVPDKKTKAKLITKAHMNLQNFKDMKKPEAIDADKFYDLDFLLQPTYYTIPSGSKLALIIYSTDQGMTKRPLEDETYTIDLANTEIKFYEK",
    "output": "Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRLLLLVGVLLAATWQVGYTRAPTFPDKSKSAADAINEPKGEHVCTVKTIVDDYELRKVIHQVVYNDTEQCLNPLTGFQCVVEKRGQKASYQRQLVQKEKYIKQCCEGYYQTKDNQCQPDCNPPCKKGKCVEPGKCECDPGFGGKICSSSCSIGTWGLGCSKKCDCENGANCDPELGDCICPSGFQGKRCEEECPIDKWGPNCVKSCPCQNGGKCNHEGKCVCTDGWGGEYCLNKCEEGKFGADCKFECTCQNGATCDNTNGKCLCKSGFHGALCEKPCSEGFFGAGCTQKCQCLNNQDCDSETGECKCIGWTGKQCDIGCARGRFGLQCKQKCTCPGLEFQDSNASCDAKTGECQCESGYKGANCDERKCSADTYGADCSKQCSCVMSNTVMCAPNTGFCRCKPGFYGDNCELACSKDSYGPNCEKQAMCDWTHASEADPANGKCVCKSGRSGANCSQPCPIDFYGPNCALQCECNGRGIGCHGFDGKCNCAPGYTGHRCEHHCPALTFGANCEKRCQCPAGVGCNPITGECECPAGRQGLKCDISCPEGSYGPECKLHCKCVNGKCDPETGECSCEPGFGGADCSTSCPKGKYGDACELSCDCSDSYCSRQTGKCICPLGKKGTLCDQPCEANTYGPQCQLTTTPSQCASTDPRNGVCLTCPPGSSGHQCEQNCPQGTYGTDCASKCACADGGHGCDPTTGECICEPGYHGATCSEKCPDGKFGYACAQNCPKCAAGSSCDHISGQCVCPAGLEGATCTRPCGVGFWGNGCRQVCRCTSEFKQCNAQTGECSCPAGFQGDRCDKPCEDGYYGPDCIKKCKCQGTATASCNRVTGVCICHPGFTGEFCHALCPESTFGLRCSKECPKDGCGDGYECDAAIGCCHVDQMSCGKAKQEFEALNGGRAKSSGATWLLILFIIGLCGVLGLAALFYRNKYQKEKDPDMPTVSFHKSPNAEDNREFQNPLYNRQSVFPDSGAFSGSSEGGVGAAPDGLLTLEEEDLEDKKIHGGGASRNMRNHDYASLDEVAGGEGGPATSSSSGVQNRRGQNSGDVRRPLLNSEDVDDDDEDEDFEEIPHENRNSTQKLSLERNSKFSEKNFKKKFLSENPYAHIPSPDPNIQNSTNSRRAQENLYT",
    "output": "Involved in programmed cell death/apoptosis. Acts by recruiting ced-6 to phagosomes which enables actin-dependent cytoskeletal reorganization and subsequent engulfment of the apoptotic cell corpse. Has a role in the association of ppk-3 and rab-7 with the phagosomal surface which is necessary for the incorporation of lysosomes to phagosomes during phagosome maturation. Activates the expression of unfolded protein response genes, which are involved in the immune response to live bacteria (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTELARLKFYATQPHSCSYLPEEQATTLFLDPSQPMDVHVYADLSEMGFRRSGDHLYRPHCQNCNACVPARIPVAQFNPNRQQKRIFKRNVDLQVRPVKPAFSEEYFDLYQRYIEQRHADGDMYPPSRDQFSTFLVRDLPFSRFYEFRLDGRLLAVAVTDLLPNGLSAVYTFYEPQEERRSLGRYAILWQIAEAQRLGLEAVYLGYWIKNCKKMNYKTQYRPIELLINQRWVVLN",
    "output": "Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MYLKSLQLRYFRNYREQVIDFAAPKTILVGQNAQGKSNLLEAVELLSTLRSHRSHRDRELVLSGQENGQIIATIERDSGPLDLTLNLRSNGRRTLMVNSEPVRRHLDFLGHLNAVEFSSLDLDLVRGTPAERRNWLDNVLIQLEPFYAHLLQQYNHVLRQRNAFLKSYQREGSLDHTELKLWDQQLASTGTRLTRRRQRLLVRLAPLATHWHQAISGKNEDLQVHYAPNVPLEGDEPEAIYQAFLEKLQQKAIAEQHQGTSLVGPHRDEVELIINQTPARQYGSQGQQRTLVLALKLAELKLIEEVIGEPPLLLLDDVLAELDLQRQNQLLETIQDRFQTLITTTHLGAFDAQWLKSAQILEVAGGVIFNSNHCDRR",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MHLQVYIVNGKRQYTLKKMDPEGKPTLSAHPARFSPDDKYSRHRITIKRRFKALKSEKRPKPL",
    "output": "Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSEMVLVGLLRGSFMFMADLCREVQVPHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILGLREPKSLAICTLLDKPSRREVDVPVEFVGFSIPDEFVVGYGIDYAQRYRHLPYVGKVVLLDE",
    "output": "Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAHCLAAVSSFSPSAVRRRLSSQVANVVSSRSSVSFHSRQMSFVSISSRPSSLRFKICCAAMGEAQAKKETVDKVCMIVKKQLAVPDGTPVTAESKFSELGADSLDTVEIVMGLEEEFNITVDETSAQDIATVQDAANLIEKLVTEKTA",
    "output": "Carrier of the growing fatty acid chain in fatty acid biosynthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNYALETNDKEIFDLIHEELDRQNTHLEMIASENFTFPAVMEAMGSVLTNKYAEGYPYKRYYGGCEFVDRVEEIAIERAKKLFGCGFANVQPHAGSQANVAVYNALLKPYDKILGMDLSHGGHLTHGAKVSVTGQTYQSFFYGVELDGYINYDKVEEIAKIVKPQMIVCGFSAYARELDFKRFREIADSVGALLLGDVAHVAGLIVAGEYPNPFPHCHIVTTTTHKTLRGPRGGMILTNDEEIAKKIDKAVFPGMQGGPLMHVIAAKAVGFGENLKPEWKEYAKQVKANAKVLAKVLMARGYTLVSGGTDNHLILVSLLDKEFSGKDADRALGEAGITVNKNTVPGETRSPFVTSGVRIGSAALTARGMREKEFEFIATKIADVLDDVNNAAKHAEIKKEIAEFAKGFPVYTKAIF",
    "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MINEIRKDAEIRMEKCVDAFKSHISKVRTGRASPSLLDGIQIDYYGLLTPLRQLANIIAEDSRTLAITVFDRTLAPAVEKAIMASDLGLNPSSAGTVIRVPLPPLTEERRRDLIKVVRAEAEQGRVSVRNVRRDANDKVKALLKDKTIGEDEDRRSQDEIQKLTDAWIKKLDSALAEKEAELMEI",
    "output": "Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSDTIRTLQGRVLSDKMDKSITVAIERKVKHPLYGKFIKRTTKIHAHDEQNQCNAGDIVTIRECRPLSKTKSWTLVEVVTKA",
    "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSNAMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV",
    "output": "The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC",
    "output": "Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation . The CRL2(PRAMEF9) complex mediates ubiquitination and degradation of truncated MSRB1/SEPX1 selenoproteins produced by failed UGA/Sec decoding ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVFSYTEKKRIRKDFGKRPQVLDIPYLLSIQLGSFQKFVKKDPEGQNGLESAFRSVFPIKSYNGNAELRYLDYKLGEPVFDVKECQIRGMTFAAPLRVQLCLVIYERDGSAYNTIKRTQQQEVYMGEIPLMTDNGTFIINGIERVVVSQLHRSPGVFFDSDKGKTHSSGKILYTARIIPYRGSWLDFEFDLKDNLFVRIDRRRKLPVTVLLRALDYTNDQILNTFFNTVVYEFKDDLLFMNLVPERLRGETVSFDIKANDIIYVERGRRITSKHINKLKADNIIKVEVPLNYLMGKVIIKDYLDIKNGELIVAANTEISMDILHNLVKSGFNIIETLFSNDLDYGNYISETLRIDSTVTRFDALVEIYRVMRPGEPPTKEAAEYLFESLFFLEERYDLSDVGRMKFNRSLQRDDISGSGVLTKNDIIDVIKKLIDIRNGKGDVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSLGDLDVLTPQDLINAKPISAAVREFFNSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYARTNKYGFLETPYRRVCDGKVSNDIHYLSAIEEGDFIIAQANTNLNKDGQFIDDLITCRNKGESGLFRKDQIDYMDVSTQQIVSVAASLIPFLEHDDANRALMGANMQRQAVPVIRSEKPLVGTGMERSVAVDSGVTVVAKRGGMVKYVDASRIVIHVNVNEISVEEAGIDIYNLKKYVRSNQNTCINQRPCVELGELIKKGDVIADGPSTDLGELALGQNMRIAFMPWNGYNFEDSMLVSERVVQEDRFTSIHIQELSCISRDTKLGPEEITSDIPNIGETALSKLDEVGVVYIGAEVVGGDILVGKITPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGICGTVIDVQIFTRDGIKKDKRALNIELTKLNQIKKDLGEELKIFESALFDRVYALLISSGVKKESLLDMNRCAWLNLKLKDITKQNQLLQLSHQYLDLKRIFEEKISIQYQKITQGDELAPGILKVVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPYDEYGVPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDQINLMLQQHQEINKLRKFIQKAYKLGVGVRQNIDLNTFSDLEVLRLAKNLKSGMPIATPVFDGATEQEIKELLQLSGLPTSGQITLFDGCTGEVFERKVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYTLQEMLTVKSDDVNGRTKMYKNIIDGNHMMEPGMPESFNVLLKEIRSLAINIELDD",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKLNDVTRGTGLEEHGIINANLIYWTPPTAVLYEQIVERGEGLVSHLGALAVKTGHYTGRAANEKFIVDEPTSRDHINWGKVNRPFDPEKFDSLYKRMTAYMHGKDLFIQDCFAGASPKHRLPIRVIAEKAWHSLFARNMFVKATAAELENHKPRFTVIDMPNFHAVPQIDGTNSETFIIINFAKRLVIIGGTSYAGEIKKSIFTVLNYLLPHHSKVMSMHCSANTGEKGDVAVFFGLSGTGKTTLSAAPNRSLIGDDEHGWDDDGVFNFEGGCYAKIINLSKESEPEIYETTRKFGTILENVAIDTISRRIDLNDDSFTENTRASYPITHIPNIVPSGMGGHPTNVIMLTCDAFGVLPPIARLTPEQAMYHFLSGYTAKVAGTEAGITEPQATFSTCFGAPFMALHPSVYAELLKAKIARHKVNCWLVNTGWSGGAYGVGSRMKIGYSRALVNAALDGTLAAGQFEKDSVFGLDIPRACPGVPGEVLNPRNVWADKAAYDATAKDLVEMFRKNFEQFKANVSQEVACVL",
    "output": "Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSATLPDVAVTEAFTLSAPLRWVGMQDIAIPVHLDAASGSGLAARASVQVDLPRAELKGIHMSRLYRLLDLHLQRPLSPAMLPQLLQALIESHADCASRAARLTLSFALMLRMPALRSEGLSGWRAYPVRIAAQCRAGRTTIQLQVEVLYASTCPCSAALSRQLLSDAFVQQHAWCDALPLQDVAQWLQDHGSYATPHSQRSVAQVCVDLPADTQGFAIQELIGLCEQALATPVQAAVRRPDEQAFARLNGANLMYVEDAARRLRKQLAEHYATFHVAVRHLESLHAHDAVAETGSDDETFFPAAL",
    "output": "Converts GTP to 7,8-dihydroneopterin triphosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MANYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQRASLRQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAPQWRGGGIVFGPTPRSYAYKMPKKMRRLALRSALSFKAQENGLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENEDVNVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKKVEEVLG",
    "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEVIQYPNSPFKLHQPFPPAGDQPTAIAGLLEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQLYAEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNLMTRNDVIIVATVSAIYGIGDPTEYQQMVLSVKEGDTIEQRDIIATLVSMQYERGDLDFKRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSLIQRVGRYTVFPSSHYVTPRDTVLRACESIKEELRERIEFFAREQRPVEQQRIEQRTRFDLEMLYEMGFCKGIENYSRHFSGKKEGEPPPTLMDYLPDNAIMFIDESHVTVTQIGGMYKGDASRKQNLVDYGFRLPSARDNRPLKFHEFEKVMPQTIFVSATPAKYEEEHAGQVVEQVVRPTGLVDPQIIIRPVATQVDDLMSEINDRIEKGERVLVTTLTKRMAEQLTDYYSELGIKVRYLHSDIDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQTIGRAARNVNGVAILYADKITDSMKAAIDETERRREKQIKFNEEQGIVPQQIKKQVKDIIDGVYHEEDGSKGRLKGKNKVKVGEIHNEEDAIKEIAKLEKAMQQAARDLQFEEAAVLRDRIRDIKENLLFGAE",
    "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGLHPCSPVDHGVPSWVLVLLLTLGLCSLQATADSVLDPDFRENYFEQYMDHFNFESFSNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSLANNSGFIVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRGYTQLLTVEQALADFAVLLQALRHNLGVQDAPTIAFGGSYGGMLSAYMRMKYPHLVAGALAASAPVIAVAGLGNPDQFFRDVTADFYGQSPKCAQAVRDAFQQIKDLFLQGAYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTNFLGPLPANPVKVGCERLLSEGQRIMGLRALAGLVYNSSGMEPCFDIYQMYQSCADPTGCGTGSNARAWDYQACTEINLTFDSNNVTDMFPEIPFSDELRQQYCLDTWGVWPRPDWLQTSFWGGDLKAASNIIFSNGDLDPWAGGGIQRNLSTSIIAVTIQGGAHHLDLRASNSEDPPSVVEVRKLEATLIREWVAAARLKQPAEAQWPGPK",
    "output": "Plays an important role in the degradation of some oligopeptides."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSAPRKVRLPSVKAVDMSMEDMAARLARLESENKALKQQVLRGGACASSTSVPSAPVPPPEPLTARQREVMITQATGRLASQAMKKIEDKVRKSVDGVTTRNEMENILQNLTLRIQVSMLGAKGQPSPGEGTRPRESNDPNATRRARSRSRGREAKKVQISD",
    "output": "Plays a role in the inhibition of host innate immune system by targeting the CGAS enzymatic activity which is the principal cytosolic DNA sensor that detects invading viral DNA . Acts by inhibiting CGAS-DNA phase separation: directly binds double-stranded DNA (dsDNA) in a length dependent but sequence independent manner and is able to form DNA-induced phase separation in infected cells. DNA phase separation of ORF52 mediates disruption of liquid-like droplets in which CGAS is activated, thereby preventing CGAS activity (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSDAKELKQVLTGPIVNNNPIALQVLGVCSALAVTSKLETALVMALALTAVTAFSNLFISMIRNHIPSSVRIIVQMTIIASLVIVVDQLLQAYAYQISKQLSVFVGLIITNCIVMGRAEAYAMKTPPMMSFMDGIGNGLGYGAILLAVGFVRELFGNGSLFGVEILHKISDGGWYQPNGLLLLPPSAFFLIGVLIWIIRTYKPEQVEAKG",
    "output": "NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAEGGAADLDTQRSDIATLLKTSLRKGDTWYLVDSRWFKQWKKYVGFDSWDKYQMGDQNVYPGPIDNSGLLKDGDAQSLKEHLIDELDYILLPTEGWNKLVSWYTLMEGQEPIARKVVEQGMFVKHCKVEVYLTELKLCENGNMNNVVTRRFSKADTIDTIEKEIRKIFSIPDEKETRLWNKYMSNTFEPLNKPDSTIQDAGLYQGQVLVIEQKNEDGTWPRGPSTPKSPGASNFSTLPKISPSSLSNNYNNMNNRNVKNSNYCLPSYTAYKNYDYSEPGRNNEQPGLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPLPMKKERTLEVYLVRMDPLTKPMQYKVVVPKIGNILDLCTALSALSGIPADKMIVTDIYNHRFHRIFAMDENLSSIMERDDIYVFEININRTEDTEHVIIPVCLREKFRHSSYTHHTGSSLFGQPFLMAVPRNNTEDKLYNLLLLRMCRYVKISTETEETEGSLHCCKDQNINGNGPNGIHEEGSPSEMETDEPDDESSQDQELPSENENSQSEDSVGGDNDSENGLCTEDTCKGQLTGHKKRLFTFQFNNLGNTDINYIKDDTRHIRFDDRQLRLDERSFLALDWDPDLKKRYFDENAAEDFEKHESVEYKPPKKPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYMRDKLDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQDTFSGTGFFPLDRETKGASAATGIPLESDEDSNDNDNDIENENCMHTN",
    "output": "Hydrolase that removes conjugated ubiquitin from target proteins and regulates various pathways such as the TGF-beta receptor signaling, NF-kappa-B and RNF41/NRDP1-PRKN pathways . Acts as a key regulator of TGF-beta receptor signaling pathway, but the precise mechanism is still unclear: according to a report, acts by promoting deubiquitination of monoubiquitinated R-SMADs (SMAD1, SMAD2 and/or SMAD3), thereby alleviating inhibition of R-SMADs and promoting activation of TGF-beta target genes . According to another reports, regulates the TGF-beta receptor signaling pathway by mediating deubiquitination and stabilization of TGFBR1, leading to an enhanced TGF-beta signal . Able to mediate deubiquitination of monoubiquitinated substrates, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains . May also regulate gene expression and/or DNA repair through the deubiquitination of histone H2B . Acts as an inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes cleavage of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains attached by parkin on target proteins such as MFN2, thereby reducing parkin's ability to drive mitophagy . Acts as an associated component of COP9 signalosome complex (CSN) and regulates different pathways via this association: regulates NF-kappa-B by mediating deubiquitination of NFKBIA and deubiquitinates substrates bound to VCP . Involved in endosome organization by mediating deubiquitination of SQSTM1: ubiquitinated SQSTM1 forms a molecular bridge that restrains cognate vesicles in the perinuclear region and its deubiquitination releases target vesicles for fast transport into the cell periphery . Acts as a negative regulator of antifungal immunity by mediating 'Lys-27'-linked deubiquitination of CARD9, thereby inactivating CARD9 .; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MERRKIMKITINYGKRLGKINKFWAKCVGSCHATTALREDWRKQLKKCRDELGFEYIRFHGWLNDDMSVCFRNDDGLLSFSFFNIDSIIDFLLEIGMKPFIELSFMPEALASGTKTVFHYKGNITPPKSYEEWGQLIEELARHLISRYGKNEVREWFFEVWNEPNLKDFFWAGTMEEYFKLYKYAAFAIKKVDSELRVGGPATAIDAWIPELKDFCTKNGVPIDFISTHQYPTDLAFSTSSNMEEAMAKAKRGELAERVKKALEEAYPLPVYYTEWNNSPSPRDPYHDIPYDAAFIVKTIIDIIDLPLGCYSYWTFTDIFEECGQSSLPFHGGFGLLNIHGIPKPSYRAFQILDKLNGERIEIEFEDKSPTIDCIAVQNEREIILVISNHNVPLSPIDTENIKVVLKGIENCREVFVERIDEYNANPKRVWLEMGSPAYLNREQIEELIKASELKKEKVSWGIVNNNEITFDLSVLPHSVVAVTIKNG",
    "output": "Beta-xylosidase is an intracellular xylan-degrading enzyme."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSEKSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGEKI",
    "output": "Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARYVFITGGVVSSLGKGIAAAALAALLQARGYRVRIRKLDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRPANQQDNITTGRIYRNIIEKERRGDYLGATVQVIPHVTDEIKNFVLQGNEDYDFVLCEIGGTVGDIEAMPFLEAIRQLGNELPRGTAVYIHLTLMPYIPAAGELKTKPTQHSVKELRSIGIAPDILLVRADREIPESERRKLSLFCNVRESAVIQALDVATIYDVPIAYHKEGLDSEVLSAFGIDPAPKPRMDRWEEVSHRLHNPEGEVTIAVVGKYTGLKDAYKSLIEALHHGGLANKVKVNLDWIEAEVFESEDPAPYLEKVHGILVPGGFGERGAEGKILAAKFARERKVPYFGICFGMQMACIEAARNLVGIEDASSSEFGPTREPVVGLMTEWLKGNMLEKRAAAGDLGGTMRLGAYEAVLKPDSKIAQIYGSTDIHERHRHRYEVNIDYKDRLEAAGLNFAGMSPDGVLPETVEYADHPWFIGVQYHPELKSRPFEPHPLFASFIEAAIEQSRLV",
    "output": "Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSFKSIFLTGGVVSSLGKGLTAASLALLLERQDLKVAMLKLDPYLNVDPGTMNPYEHGEVYVTDDGVETDLDLGHYHRFSSVQLSKYSIATSGQIYTKVLTKERNGEFLGSTVQVIPHVTNEIINVIQSCADHHKPDILIVEIGGTIGDIESLPFLEAVRQFRCEHPQDCLSIHMTYVPYLRAAKEIKTKPTQHSVQNLRSIGISPDVILCRSEAPLSTEVKRKISLFCNVPEHAVFNAIDLERSIYEMPLLLAKENISDFLLNKLGFSPKPLDLSDWQDLVEALCDKERQHVRIGLVGKYLEHKDAYKSVFEALFHASVPANCSLELVPIAPESEDLLEQLSQCDGCLIPGGFGTRSWEGKISAARYCREQNIPCFGICLGMQALVVEYARNVLDKPLANSMEMNPETPDPVVCMMEGQDSVVKGGTMRLGAYPCRIAPGSLASAAYKTDLVQERHRHRYEVNPSYIERLEEHGLKIAGVCPLGELCEIVEIPNHRWMLGVQFHPEFLSKLAKPHPLFIEFIRAAKAYSLEKANHEHR",
    "output": "Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQAGEIWHISASPADRGVLATCYNRTSDSKVLTCAAVWRMPKELESGSHESPDDSSSTAQTLELLCHLDNTAHSNMACVVWEPMGDGKKIISLADNHILLWDLQESSSQAVLASSASLGGKGQLKFTSGRWSPHHNCTQVATANDTTLRGWDTRTMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWNVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDISDQEDHRSEEKSKEPLQDNVIATYEEHEDSVYAVDWSSADPWLFASLSYDGRLVINRVPRALKYHILL",
    "output": "Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network (By similarity). Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein (By similarity). Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex (By similarity). Controls proper insulin distribution and secretion, and retention of cargo in mature dense core vesicles (By similarity). Required for the stability of the endosome-associated retrograde protein (EARP) complex subunits and for proper localization and association of EARP with membranes (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNETSNRDHQVTSKEILDVAFEKSKSKFTTPRQTIQDTEELQSYQQTKRKEFEQHINKNRLNLGQWTRYAKWEIENNHDFPRARSILERALDVNIQHVPFWIQYIQLELSHKNINHARNLMERAINTLPRVNKLWFLYVQTEEMLKNYPMVRAVFERWLDWHPDTSAWDAYINFEARYEEKENVRTIFKKYVHEFPNAGTWYKWIKYEMENNRDDVNTVRAVFESAVDTLLSNKSEENDDDEEFATIISSWTSWEVSCGEASRANEIFKLLLDNKTNKLEISDQTKSSIYTAFVEFEKNFGNKDSIEQSVLIKRRIKYEQEIQNDPYDYDSWWKYMTLLQNSSNKSDLENAFKKVTGNVVHDKHKSIKWRRYIMFWIWYAFWEEMTNNNPVSAREIWNNCLKVIPHKSFTFAKVWIGYSEFELRNSEDGLAKARKILGRAIGQTSINKPKIKIFKYYIDLEKKLGDWNRVRLLFQKWLEVSLLTTSSSELVIEKYVEFESSIEEYDRCDSILSSARQLSENPEYSSSFNLQRLLEITVEFYKEEMQYDKIREIYRALLDKDPNAHNWISFALFESSIPSAEQLEEYLQGDNEEFEATVDESQIESTRNIFEEAMTYFKDKDDKESRLVIIEAWRDFEEVNGSDESLSKVTKRLPVIVRKRRTVGSIEEEYIDYIFPDDESKKLPGKMSKFLANAKKWAQQN",
    "output": "Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNIFRLTGDLSHLAAIIILLLKIWKSRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLIVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRYYFEGFFDLIAVVAGVVQTVLYCDFFYLYVTKVLKGKKLSLPA",
    "output": "Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi (By similarity). Binding is pH dependent, and is optimal at pH 5-5.4 ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKSTVTKIAEKTYQLPVSYKDCMRVPGNVYLDELLFENLQEDVFEQIANVACLPGIQKYSLAMPDCHYGYGFCIGGVAAFDEVTGVISPGGVGFDINCGVRLVKTNLTKNDVTPKLKELLSEIFKNVPSGLGSKGKIRITKDEIDSVLEEGVSWAVEEEYGWERDIKHIEEHGKMKEADPTLVSDNAKKRGLPQLGSLGSGNHFLEVQYVDEIFDEEAAKTFGVSPDQVVLMIHTGSRGLGHQICADYLRYMENAAKKYNIKLPDRQLACAPINSEEGQKYFKAMSCGANYAWANRQLITHWIRESFESVFKTSAEDLEMDIIYDVAHNIAKKEQHLVDGVLKNVVVHRKGATRAFGPGHAEIPSDYVNIGQPVIIPGDMGTASYLMHGTEKAMEQTFGSTAHGAGRALSRVKALKLYTGNEVQEALQKKGILVMADSKGVIAEECPEAYKDIENVADICHDSGISLKVAKMKPMGVVKG",
    "output": "Essential for tRNA splicing and maturation. Acts by directly joining spliced tRNA halves to mature-sized tRNAs. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREKREKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFSGDDLLPLDHWVFNTEAHPLPVLHLANTTLSGNPAVR",
    "output": "Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTATLDVPEQNPDLVLDQSADDYWNHYQLTFALYSVSDRAIPSAYDGLKPGQRRLLYQMHDSKLLPGNKPQKSSKVCSAVTGNLHPHGGASMYGAAALMAADFQRVKVIDGQGAFPRIQGDIPAADRYTEMRLSAPGAALTAELNDHAVPMVPTFDGEWVEPTVLPAQWPVLLCNGAVGIAEGWATKVPAHNPREVMAACRALLKTPNMTDDRLCKLIPGPDWGSGASVVGTAGLREYITTGRGHFTVRGTISVEGKNCIITELPPGVASNTVQDRIRALVESGEMSGVADMSDLTDRRNGLRIVVTAKRGHNAEQIRDQLLALTPLESTFAASLVALDENRVPRWWSVRDLIMAFLQLRDSVVLHRSEYRLEKVTARRHLVAGLMKIHLDIDAAVAVIRGSETVDEARKGLQERFKIDAEQADYVLSLQLRRLTKLDVIELQAEAEKLDAEFAELNDLVTNPESRRKVIDKELVETAKLFKGPEYDRRTVLDFDATPVSRGDEDGSRERKVNTAWRLDDRGVFSDSHGELLTSGLGWAVWSDGRIKFTTGNGLPFKIRDIPVAPDITGLVRSGVLPEGYHLALVTRRGKILRVDPASVNPQGVAGNGVAGVKLAADGDEVIAALPVSCANGEAILSIAEKSWKVTEVADIPVKGRGGAGVAFHPFVKGEDALLAASISKTGYVRGKRAVRPENRAKASIKGSGADVTPAPAE",
    "output": "Catalyzes the relaxation of negatively supercoiled DNA in the presence of ATP or dATP but not other nucleotides. Individual subunits have no activity. Not able to negatively supercoil DNA, it can however introduce positive supercoils in DNA. Relaxes positive supercoils in an ATP-dependent manner. Catenates and decatenates DNA. Generates dsDNA breaks in the presence of the quinolone antibiotic ciprofloxacin, showing it is a topoisomerase ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGRAPCCEKMGLKRGPWTAEEDRILVAHIERHGHSNWRALPRQAGLLRCGKSCRLRWINYLRPDIKRGNFTREEEDAIIHLHDLLGNRWSAIAARLPGRTDNEIKNVWHTHLKKRLEPKPSSGREAAAPKRKATKKAAAVAVAIDVPTTVPVSPEQSLSTTTTSAATTEEYSYSMASSADHNTTDSFTSEEEFQIDDSFWSETLAMTVDSTDSGMEMSGGDPLGAGGASPSSSNDDDMDDFWLKLFIQAGGMQNLPQI",
    "output": "Acts as negative regulator of cold tolerance. Negatively regulates beta-amylase genes at the transcriptional level in response to cold stress. Suppresses beta-amylase gene expression by interacting with TIFY11A/JAZ9. Maltose produced by beta-amylases has a role in protecting cell membranes under cold stress conditions in rice and may contribute to the cold tolerance as a compatible solute."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "QRYNPYKYIELFLVVDNRMVTKYNGDLDKIKTRIYELVNILNEIYRPLYIRVALVGIEFWCNKDLINVKSASSVTLASFANWRESVLPNRTSHDNAQLLTAIVFNRGVIGSAYPAGMCDPNRSVGTVQDHSEINLQVAITMAHEIGHNLGMGHDNNSCTCGGYSCIMLPALSDQPSKYFSNCSYIQYRDFIMNQDPQCILNEPSGTDIVSPPVCGNDILEVGEECDCGCPRNCQDPCCNAATCKKYSWVQCESGECCDQCRFKGAGTECRRAMGDDPGGRCTGQSADCPRN",
    "output": "This hemorrhagic toxin hydrolyzes the Aalpha-chain (FGA) and more slowly the Bbeta-chain (FGB) of fibrin and fibrinogen. Also hydrolyzes casein. It lacks platelet aggregation inhibitory activity. After intramuscular injection, it acts rapidly to disrupt the capillary endothelium without damaging the intercellular junctions, and also appears to damage skeletal muscle cells. Cleaves insulin B chain at '27-Asn-|-Gln-28', '34-His-|-Leu-35', '38-Ala-|-Leu-39', '40-Tyr-|-Leu-41', '46-Arg-|-Gly-47' and '48-Phe-|-Phe-49' bonds ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSSESGKPIAKPIRKPGYTNPALKALGIPALRLPSRNWMIFWSVLTVSIGGIAYDKYKQRQILSHATDLVKPLAEESMEVDKVPRKITVFIAPPPNDYLESSLKVWRRYVKPVLYYAGLDYELVQEDRQGIIRTNVANRIRELRKEILASTDGQPVKEPNQTVAKPSGSSTSKISSLLPFNKIIQDPAEEDDSFDPEIGKKFKENFDWRNVIGIFYTMPKPKHIISEDALTKDPILSGGVICLGRGAYKEYIAGIHEGLLGPIEKTEKTGSTEPKMTGVVEANQIESKVSESGATELVDAEKETALEEAKVQDDLKVDEENSSEDSQKFLKPFISSDQYPDLQIASELQTPNGEFIRNPNTNIPLLINQPLLVIPIPNLIGFTTIPRRIHRFYQKRFYVEDVCSSVVNCVRQTRIRPFDIAKDIDLAKDEEKDWPQNWVKQGKEKNSEWTQELVCDPRITKHMFVYEKPPKEEPESDI",
    "output": "Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force. Its precise function within the TIM22 complex is unclear."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVKTWEEFLKQEAKQPYFIELMEAVKDARAKGNVYPSEEDMFSCFRLCPYNQVKVVILGQDPYHGPGQAHGLSFSVQKDVRIPPSLRNIYKELKTDLDIEPADHGYLAKWAEQGVLLMNTSWSVEEGKAGSHKKLGWATFTDHVLEELNNYDKPLVFILWGNHAIKAASGITNPQHLIIKGVHPSPLAASRGFFGSKPFSKTNAFLEEHERKPIDWDLNEQ",
    "output": "Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARYIGPSCKLARREGADLSLKSPSRALDSKCKLEQRPGQHGAVRKSKLSDYASQLREKQKVKRIYGVLERQFRNYYKNASTKKGNTGENLLQLLETRLDNVIYRMGFAVTRPAARQLVSHRSVLVNGKMVNLPSYHVKPGDVVALSQRAQKYLCVQESLTIKDQHGSAFSWIEVDSEKFSGVFKALPDRADLPSDINEALIVELYSK",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQTPPVKDGPRINEDIRVPRVLLIDHNGEKQGEMPISAALEAAEEAGLDLVEIVPNANPPVCKILDYGKFKFQEQKKKNEARKRQKIVELKEIKLRPNIDIHDYDVKAKSMHRFFEEGDKVKVTLRFRGREMAHPELGMKLLLKVKADFDEIAKVEYEPRMEGRQMIMILAPR",
    "output": "IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSVTKKPDLSDPVLKAKLAKGMGHNTYGEPAWPNDLLYMFPVVILGTFACVIGLSVLDPAAMGEPANPFATPLEILPEWYFYPVFQILRVVPNKLLGVLLMAAVPAGLITVPFIESINKFQNPYRRPIATILFLLGTLVAVWLGIGSTFPIDISLTLGLF",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRNLAVFGTASDVGKSVVATALCRIFSNAGLDVAPFKAQNMSNNSGVTPDGLEMGRAQIVQAEAARVVPTADMNPVLLKPNTDTGAQVVLQGKAVANRSARDYFGNTEVWAEAAFESLERLTGRHDLVVIEGAGSCAEMNLYDRDFVNFRTAKEADAPVILVADIDRGGVFAQVAGTLSVIPPEDRARVKGVIINRFRGDSVLFDDGIRILEELSGVPVLGVIPYFRGIHIEAEDAVPLQAVVDPAASPDPGKISIAIVYFPHISNFTDFAVFDLLDDAEVHYLHHPKDLADYDAVILPGSKNVRGDLDWMIFMGWKERLAEYRKRGGIIAGICGGYQMLGISVADPHGLEGEPGETSGLGLLPVHTLLKKEKQLFNAKGCLFDDTIPVEGYEIHMGETRLTGKASPLLQLTARNNRHSSDTDGVISHDEKVFGTYFHGIFDGSAFRGWFLGKLRPDSAVNDTITEKDTEYNRLAEHFLSHLNMGKVYEIIGRGK",
    "output": "Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSRDGVPTPQDIIKVLDEYVIGQRQAKKILSVAVHNHYKRLAHASKNGEVELAKSNIMLVGPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDVENIILKLLQSADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDKIISARGEKTSIGFGATVKAQDDRRVGEVLRELEPEDLVKFGLIPEFIGRLPVLATLEDLDEDALIQILSEPKNALIKQYQRLFEMEDVELTFHEDALREIARKAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISEEVVRGSARPLYIYADRQEEKANASA",
    "output": "ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MATKSTSKPLLLSFLMMSYLISTFHVITVAEGRTLQFTKMATDHSGAGNLMDCWNAGLELKSCTDEIVKFFLSQTGTSEPPVKGGIDKDCCGAIGLVVKDCWSVMFTSLGLTTMEGNNLREYCEFQAEKSELSPSPAPETLALSPVEITYPGLDY",
    "output": "Involved in the regulation of gamete interactions during the double fertilization and to prevent multiple-pollen tube attraction; mediates the redistribution of the gamete fusogen HAP2/GCS1 to the cell surface after secretion upon sperm arrival."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSKLDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYIKSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPEHSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSKIQEAFKDRILIPKNNLDYVPKKNKVLHSFEQQKIEFEQRQNTENNQEKTFSSEESNSKPFMEENQNDEIVIKEDSYNPFVTKTSESLIADDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNDGTTVQNYENKASDDYYDVNDIKGTKSKDPKRRIPYMEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIMLEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREAEDPFTCPHGRPIIINFSKYELEKLFKRVM",
    "output": "This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKPYFCRVFVFCFLIRLLTGEINGSADHRMFSFHNGGVQISCKYPETVQQLKMRLFREREVLCELTKTKGSGNAVSIKNPMLCLYHLSNNSVSFFLNNPDSSQGSYYFCSLSIFDPPPFQERNLSGGYLHIYESQLCCQLKLWLPVGCAAFVVVLLFGCILIIWFSKKKYGSSVHDPNSEYMFMAAVNTNKKSRLAGVTS",
    "output": "Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAQQTFTGRKRVRKFFGHIREVAEMPNLIEVQKASYDQFLMVEEPVGGRLDEGLQAVFRSVFPISDFSNTSMLEFVRYEFEPPKYDVDECRQRGMTYAAPLKVTLRLIVFDIDEETGARSVKDIKEQDVYMGDIPLMTMNGTFVVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAARVIPYRGSWLDIEFDAKDIVFARIDRRRKLPVTSLMFALGLDGEEILSTFYKKIIYKRTKEGWRVPFDANRFRGYTTTNDVIDADTGKVVLEAGKKLTVRAARQLQEKGLKALRMTDEDIVGNYLAEDLVNPKTGEIYAEAGEEITEKSLKALNEQGYKDLTLLDIDHVNIGPYIRNTLAADKNMTREDALFDIYRVMRPGEPPTLDSAQNMFQSLFFDSERYDLSAVGRVKMNMRLELDAPDTHRTLRKEDILAVIKTLVGLRDGRGEIDDIDHLGNRRVRSVGELMENQYRIGLLRMERAIKERMSSVDIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFVETPYRRVKDGRVTDEVVYLSAMEEGRYAVAQANVQLDPKGRFVEDLIVCRDGGTRDVVLIPADKVDFMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRAEAPFVGTGMEGVVARDSGAAIAARRTGVVDQIDATRIVIRATEDLDPTKSGVDIYRLMKFQRSNQSTCINQRPLVKVGDQVAKGDIIADGPSTDLGELALGRNVLVAFMPWNGYNFEDSILLSERIVKDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVRAGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVPPGVQGTIVEVRVFNRHGVDKDERALAIEREEIERLAKDRDDEQAILDRNVYGRLADLLDNRQGIAGPKGFKKDTKITRAVLEEYPKSQWWMFASPNDKLMAEIEAMRKQYDESKKGLEQRFLDKVEKLQRGDELPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSKIVPIEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLGWACAGLGKRIGQTIDAYYQKQDLKPMRETLKKIYGDDETIKSLNDAELIELARNLKPGVPIATPVFDGAKEADIEEMLHLAGLDASGQSTVYDGRTGDSFDRKVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVDLHNSKLAGTPSEAAE",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKPDVLLYNSQHLINNITLYQLNHINIASFSFVFFSGLFTSFSPCLISILPICIMYISGEGQKLSQIDKLKNLFFFCLGAISSFTTLGLIATLLAKTYSQLFNGIPVISALVIIYMGFSLLNIVPLSTNNLNTRINNTNQNIKMYLSGVGIGLAISSCSTPIFVTLLIWVTSNHNLFIGLIFILIYSIGYIFPIIIGSLFSSRFLTTASSPFLNNLWAPFSGTILLSAGTFSLFSSILKY",
    "output": "Could be involved in cytochrome c synthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "EVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAEESEIENEPVVGIGAEALKQLLEDLNLEEVAEQLREEINGSKGQKRAKLIKRLRVIDNFVATSAR",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPMRKRHFYRLLPLASLLLAACTIPVSKGPATSPTSPQWRQHEQQLQQLGQFETRGAFAYLSDKQKVYARFFWQQTSPERYRLLLTNPLGSTELELVVQPGVTQLTDNQGKRYVSDDPQEMIQKLTGMSIPLESLRQWILGLPGDTPNFTLDDKYRLKKLTYQQNGVTWVVDYQEYNTQVTPPLPSRLELNQDGQRIKLKMDSWTIK",
    "output": "Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAHYSKVDLDEEFERFMKELSDDSFENSNETPSQPNKDRKKKDTAPWWIAEDGFEDDGLLGTNVSYLKTKKTYQPITDMEEENEKVQFLKSSGTSVLSVDSLEANELVASELHHSTLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSKLNQELDSDDSAQFRVLHRYQGNVEPAEGGRENESEHKELPETYSDDFEDAEDTDEPLITKDEETRPKENPESGKGSFPNQEEEKTGMLANVVLLDSFDSVEDVDLNNHERPTPKAKALPEMAGGELAETGVSYGQSSGDTEALHQAYHHVAHSLGDTGEPRIEASPGHSVRSSAKDGLQENEESSKNISTTESDLPTVEELMKPIRIDSYGIRGFDLQPVSLQKAVGSKEAESVSSLPLTVNTNTMSQDTRHVSPFPHEQDESVVLHRTAGEGVGSSCPATEEHLDKMYLEILRKKTSVNPSLLPQDNKANQTSRSRLSAREEAPVTSKQVPCKKARSAPPLPRRKPQSGLYASARSSGYSKPSSPLQFFSALEKKTSKDNTKTKNVRPIPTSNQFRKREILSGTKLIKPAALNKPSPHREGSPATPKRPEDPSDDSFVQLQTETLGSYGGNREKELLMLKRAQDAEEKWRGAQALIEQIKMTFSEKEKELENTVESLKRQQERELFKLNQENYILQAKLSSFEETSRKQRWLQFGETSDPLTEEKLKQIQKEIQEQETLLQGYQQENERLYSQVKDLQEQNKKNEERMFKENQNLFSELASLKEQMHKNHFLPQAVENIEPTKNQSFTDLLAELRAAQKEKNHLMEDIKRLKQDKQALEVDLERVKRERDQAKDQIAYTTGEKLYEIKILEETHKQEVSRLQKRLQWYAENQELLDKDAARLREANEETERLKLEIEKLKTESGSPANQQRLRSKERALDAKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDSVDRNTVDFMERRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQMLAHRQREAPQNQHNSSSRLKALETELGGIKEAHQITVRKLEAEIDVLKHQNAHLEHKKNDKEDQDLQSIEFQVEQAQARAKLARLNEELAAKGREIQDLTKTVERLQKERRMMLSRQSPRGREEMAAKRLKKEILHPNSGNANAFSETLGAKLYHPHTFTDSHISEVLEENYRLRSELEGLTLEREKLKMESEAAVCQLESSMKRVKDDAAAHIASLKAAHEREIEKLLCQNAVENSSSRVAELNRKIATQEVLLKHFQGQVNELQGKQESLSLSQVREEILQKQITKLLEELKEAKENHTPEMKHFMGLERKIKQMEMRHKQREQELQQIIQQTRQVVETEQNKEVEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPVALADEESTAKEF",
    "output": "Required to promote assembly of the transition zone in primary cilia. Acts by specifically recognizing and binding the axonemal microtubule. Localizes to the distal ends of centrioles before ciliogenesis and directly binds to axonemal microtubule, thereby promoting and restricting transition zone formation specifically at the cilia base. Required to mediate CEP290 association with microtubules (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRTQRLKKLALVCALGFACITTAQAAERIAFIPKLVGVGFFTSGGKGAVDAGKALGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIVVSAVSPDGLCPALKRAMQRGVKILTWDSDTKPECRSVYINQGTPNQLGSMLVDMAANQVKKEQAKVAFFYSSPTVTDQNQWVNEAKKKIQQEHPGWEIVTTQFGYNDATKSLQTAEGILKAYGDLDAIIAPDANALPAAAQAAENLKRANVAIVGFSTPNVMRPYVERGTVKEFGLWDVVNQGKISVYVANEMLKKGDLNVGDKIDIPNIGVVEVSPNRVQGYDYEAKGNGIVLLPQRVIFTKENISKYDF",
    "output": "Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSAKNNIQDQLLNTARKEKIDLTIYLLNGVPLKGKVVSFDNFTIILENENKQNLVYKHAISTIIPAKPIKLHSEETPKEAGGV",
    "output": "RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKLIAFDQDAREGILRGVDALANAVKVTLGPRGRNVVLDKAFGGPLVTNDGVTIARDIDLEDPFENLGAQLVKSVAVKTNDIAGDGTTTATLLAQALIAEGLRNVAAGANPMELNKGIAAAAEKTLEELKARATEVSDTKEIANVATVSSRDEVVGEIVAAAMEKVGKDGVVTVEESQSIETALEVTEGISFDKGYLSPYFINDNDTQQAVLDNPAVLLVRNKISSLPDFLPLLEKVVESNRPLLIIAEDVEGEPLQTLVVNSIRKTIKVVAVKSPYFGDRRKAFMDDLAIVTKATVVDPEVGINLNEAGEEVFGTARRITVSKDETVIVDGAGSAEEVEARRAQIRREIANTDSTWDREKAEERLAKLSGGIAVIRVGAATETEVNDRKLRVEDAINAARAAAQEGVIAGGGSALVQIAETLKAYAEEFEGDQKVGVRALATALGKPAYWIASNAGLDGSVVVARTAALPNGEGFNAATLEYGNLINDGVIDPVKVTHSAVVNATSVARMVLTTEASVVEKPAEEAADAHAGHHHH",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKQFLDFLPLVVFFAFYKLYDIYAATSALIVATAIVLIYSWVRYRKIEKMALITFVLVAVFGGLTLFFHNDEFIKWKVTVIYALFAGALLISQWVMKKPLIQRMLGKELALPQQVWSKLNLAWALFFIACGLANIYIAFWLPQNIWVNFKVFGLTALTLIFTLLSGVYIYRHLPQEDKS",
    "output": "Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MMNISNVSIALYLCTLFAFVSSDSPEAMRDLVTNFPGQPKVSFRHYAGYVTVNIISGRALFYWFFEAMTHPNVKPLVLWLNGGPGCSSVGYGATQEIGPFLVDNKGNSLKFNPYAWNKEANILFLESPAGVGFSYSNTSSDYRKLGDDFTARDSYTFLQKWFLRFPAYKEKDFFIAGESYAGKYVPELAEVIYDKNKDNENLSLHINLKGILLGNPLTSYAEDWTGWVDYAWNHAVVSDETYRVIKQSCNFSSDTTWDVKDCKEGVDEILKQYKEIDQFSLYTPICMHHSSKVDSYANYKTTIPRLFDGFDPCLDDYAKVFYNRADVQKALHATDGVHLKNWTICNDDILNHWNWTDSKRSVLPIYKKLIAGGFRVWVYSGDTDGRVPVLSTRYCINKLELPIKTAWRPWYHETQVSGWFQEYEGLTFATFRGAGHDVPSFKPSESLAFFSAFLNGVPPPLSR",
    "output": "Probable carboxypeptidase."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKSSKRRPAPEKPVKTRKCVFCAKKDQAIDYKDTALLRTYISERGKIRARRVTGNCVQHQRDIALAVKNAREVALLPFTSSVR",
    "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNQKILEQLEFQKVKEQFQPYLQTAQGIQELRLLEPSNHYDKISDYFKEIAEMATIFVENHHFSIGNLRDVSESMRRLELEADLNIQELLDIKKLLLVSGEISRFYQDLENVDLQVLKRIFEKIEVFPQLQGSLQAVNDAAFIENFASPELDRLRRQIAENERYSRQLLQDILKKNADYLSESLIASRNGKSVLPVKNTFRHRVSGVVHDISASGNTVYIEPRALVQVNEEMTQLLADERHEIARILKELSQLLRPHSRALANNAWLLGHLDFVRAKYHYLVNNKATIPKISKDKNIQLLNVRHPLLKNPVANDLHFADDLAVIVITGPNTGGKTIMLKTLGLAQLMGQSGLPILADEGSKIAVFDAIYADIGDEQSIEQSLSTFSSHMTHIVDILEESNSNSLVLFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYGIESDYVENASMEFDSQSLKPTYRFMQGVPGRSNAFEIARRLGLAETIVKEAEQMTDTDSDVNRIIEELERQTLSSRRRLDHIREVEQENIKFNRAVKKLYNEFSLAKDKEIEKASQEAQAIVELALTESEEILSKLHEKAELKPHEIIEAKSKLKSLVPQRDLSKNKVLKKAKKLREPRIGDDIIVSAYGQRGTLIGQVKGNKWEAQVGLIKMTLKEDEFQLVKVEAEAQKPKKQSINMVKKANQNGPRARLDLRGKRYEEAMQELDAFIDQALVNNMSQVDIIHGIGTGVIREAVTKYLRRHKHVKSFAYAPQNAGGSGCTIATLG",
    "output": "Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNTVRVTFLLVFVLAVSLGQADKDENRMEMQEKTEQGESYLDFAENLLLQKLEELEAKLLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK",
    "output": "Probable ion channel inhibitor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTATASHTRARPLGASEIEHATRIAEPDFDLLDALYRTDDPDDQARLLARVVLSAFDNYYAVSRRIPALAQAAFEARDWPVTVRLSKIRIGLYTACIDQLVPLLKAGLPELTTDEQLWPTAEAELLAAIEGRYEADFAFAFWQSLRRKLVSDEWRPVSYDAGSTARRTTSPAAVLKTTTTTLPITAEVIAGILGDAGFRVPWRDRDGDAALAAQAIETALEPLSPRPGEPVKIEIADAGFFRNRGACLVGRIQLRDRGDMPMRNLPLLIALLNEKDGLVVDAVLTDSDELQYAFSSTLANYHATNPRYHELARLLYELMPKRPLGTQYSCIGFHHLGKVAVMSEILAEHRKTKERLATAPGFKGTVAIAFTMPSSAYVLKIIRDHPTDDYKFDYFDGLDEVLRKYNLVHEIDRAGSMLDNIIYSNVKLDRAMFAPELLDELLEAGIGTVTLDRGALVFRHLIVQIKLTPLPLYLANASAAESRAAVINLGDCIKNNAAADIFNKDLDGRNYGVSRIRKVYLFDYDAVEPLTSVTVSRDGAAPGEFDNGMVFRPQEMLEGLRIDDPGLRRAFRDAHPELMQADYWEGMQRALRDGKVPKVMNYPASRRLQR",
    "output": "Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAGAASPCANGCGPSAPSDAEVVHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIRGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRTSDITYGQFAQLYRSLMYSAQKTMDLPFLEASALRAGERPELCRVSLPEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSIWNSQLDEVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASGSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAVRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFLAGGHCGYVLQPSVMRDEAFDPFDKSSLRGLEPCAICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSIKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEGLELASLLVKIDVFPAKQENGDLSPFGGASLRERSCDASGPLFHGRAREGSFEARYQQPFEDFRISQEHLADHFDGRDRRTPRRTRVNGDNRL",
    "output": "Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Plays a role in actin reorganization and cell migration (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNIKTIEGNLSAKDSKFAIVTSRFNDFIGGRLVEGALDCIVRHDGSEENIAIYKCPGAFEVPMVAKKLAQSGKWDAVIAIGVLIRGATAHFDYIAAEATKGIAQASLECGVPISFGVLTTDTIEQAIERAGTKAGNKGWDAASAAIEMVNLYKQM",
    "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MCFWTNLSVWMILLSHSLSLVSSTETGKTLTQNNSRAGSQGLLEVLRVLSAGDHWSLNHPQSLIKILLERTGCPQRTDWTQGDCKLCLEADALLLTAGGNLEDELREEVVQRVSLLLLYYIIHQEEICSSKLNMSNREYEFYLHSLLGLRQDEDSYFLSEKETDDILAFTRKYFGTSSSQCMETKILQRESGIQGSNGADEKTLPQLAATIIALSLQGVCLGRKALPSPDDFTEYIFSFLNSTNTLHLSEIEQLLNMLTTRRTCAKEDKYLHQYQRKQNTEEHSLRDPKTSTAMDKESDDHSPSWDQACFSARQLVEIFLQNHSSLSISKEDFKQLSPGIIQQLLSCSCQMPKDQQAKPPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYSLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAEFGHFHESQSPIWKLLGLLGGIHGFFLIEKCFILLVSPNTKGLPLVNEHVGHTHHLGLNPELNDQSSGGKSISTIQLKGPEDSQTTVLPIGNVPASNRNGKTISLLAIMILVGDSLHNFADGLVIGTAFSSSLESGVTTTIAILCHEIPHEMGDFAVLLSSGLSVRTAILMNFLSALTAFAGLYIGLSVSADPRVQDWILTVTAGMFLYLSLVGMLPEMTHVQTQRPWMTFLLQNVGLVLGWFSLLLLAVYEQNIKI",
    "output": "Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane . The transport activity is temperature dependent . May play a role in neurulation and neurite extension . May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAEDDLCSLFFKLKVEDVTSSDELARHMKNASNERKPLIEPGENQSMDIDEEGGSVGHGLLYLYVDCPTMMLCFYGGSLPYNWMQGALLTNLPPYQHDVTLDEVNRGLRQASGFFGYADPMRSAYFAAFSFPGRVIKLNEQMELTSTKGKCLTFDLYASTQLRFEPGELVRHGECKFAIG",
    "output": "Hydrolyzes cytokinin glucosides thus liberating free cytokinins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIKGTGHMIVNIANDRGMSIDSIRKTIKESVLIAYKKYFGSNENAFIKFDDDTGDLSVYAKKKIVKEVKDSLLEILEKDISKENIVEGDYAYIEINPKVFDRLSIQVAKQRTKNDLQGIEDNEILSEFKSKLNKVVIGYVQQNRNGDLYVNLGNTDGIIPKKYQSPREVYNLNDKIRVLVYNVKKGKNGIEVILSRTHPKFIEELLALEIPEIEEGIIKIHKIVRDPGYRIKVAVYSEKEEIDPVGPCIGQKGVRIQSIIKELEGEKIDIIPYSKDIKEFIKDSLTPSKIEHVYILDEDLHKALVVVSDDQLSLAIGKMGQNVRLANRLLDWAIDVKTSSQFAEMKANSEFKQETLEMFDKVMQDVVEEEQFEEISKISDLKLLDPSVISNLSKEGFDDINNFLQADEGVLFNLGVSYEKQEEINKILKEGMIIIANDNDESMEKVEEDEELLCPECGVVINENMTSCPGCKIGLSFEFEEE",
    "output": "Participates in both transcription termination and antitermination."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSDIIRLLPDNIANQIAAGEVVQRPASVVKELLENSVDAGSTNIQLIVKDAGKQLIQVIDNGKGMSDGDARLCFERHATSKIRSADDLFAIRTFGFRGEAMASIASVAQVEMKTKLPGNELGTLIRIEGSAILVHEQTAHPQGTSISVKNLFYNVPARRNFLKSNSVEMRHIMDEFVRVALAHPEVAFSFYHNDLELFNVPEETLSKRAVSLLGGSYREQLIPCKEETDFVSISGYIGKPESARKTRGDQYFFVNNRYIRSNYLHHAVMHAFEELIPTDAFPFYLLFIEIDPAHIDVNVHPTKTEIKFDDEKTVYAIIKACVKRSLGTHNIMPSLDFDFNVNVSGFTGMGLSDSSGRESNTNFTPKSFSTSDSIQRSNQSNWERMYSGLENNREEVYQESIKMVSAINGTEDLKQLSKEQLYTENTSTFQLHQKYIVTQVKSGVLLVDQQAAHERILFEKYIGMLQNRFGSSQQFLFPQTLELSAADFAMVVEMEEDIRKLGFVFNVFSNTTIVVNGVPSDVKSGNEKNLFEGLIEQFKQNRTDLKIDRQENLARSLAKRSAIRAGNKLSLMEMNSIIDQLFACKSPNYAPDGNLTVVMLDMDKIGRLFM",
    "output": "This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MALHDENVVWHSHPVTPQQREQHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS",
    "output": "Catalyzes the synthesis of activated sulfate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPAQDVLTRKTGVIVGDDVKALFDYAKEHKFAIPAINVTSSSTVVAALEAARDNKSPIILQTSNGGAAYFAGKGVSNEGQNASIRGSIAAAHYIRSIAPAYGIPVVLHTDHCAKKLLPWFDGMLKADEEYFAKHGEPLFSSHMLDLSEETDEENIGLCVKYFTRMAKIHQWLEMEIGITGGEEDGVNNEGTSNDKLYTTPETVFSVHEALSKISPNFSIASAFGNVHGVYKIAAALKPELLGTFQDYAAKQLNKKAEDKPLYLVFHGGSGSSTKDFHTAIDFGVVKVNLDTDCQFAYLSGIRDYVLNKKDYLMTPVGNPTGEDSPNKKYYDPRVWVREGEKTMSKRITQALEIFRTKGALE",
    "output": "Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLKPLGNRVIIERKEQEQTTKSGIVLTDSAKEKSNEGIVVAVGTGRVLDNGEKVAPEVKEGDRVVFQEYAGSEVKRGDKTYLILNVEDLLAIIED",
    "output": "Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MALSVEEKAQIVAEYQQAAGDTGSPEVQVALLTANINKLQGHFKANDKDHHSRRGLIRMVNQRRKLLDYLKGKDTTRYSALIGRLGLRR",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSCRSEHIWIELIVGSRKISNFCWAFILFLGSLGFVLVGSSSYLGKNLISLVPSQQILFFPQGIVMSFYGIAGLFISSYLWCTISWNVGSGYDRFDRKEGIVCIFRWGFPGKNRRIFLRFRMKDIQSIRIEVKEGISARRVLYMEIKGQGAVPLTRTDENLTPREIEQKAAELAYFLRVPIEVF",
    "output": "Seems to be required for the assembly of the photosystem I complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEAKDHIERRPDRVSIRRLKLVNFRNYAELSLPLGPGHVVLTGENGSGKTNLIEAISFLSPGRGLRRAAYDDVARANAEGGFAIHAALDCMIYGDAEIGTGTAGGGEGGRKVRINGIAASADDLLDYARILWVVPSMDGLFTGGASDRRRFLDRMVLAIDTAHGKRVLDYEKAMRSRNRLLNDGSNDDQWLDAIENQMAELGTAIAAARAQAMRLIAAMIERLPAEGPFPKADCFLEGALESRIGVEAALDLEEDFRRTLRDGRARDRAAGRTLDGPHRTDLIVQHRPKSMPAALCSTGEQKALLIGLILAHARLTAELSGMAPILLLDEIAAHLDMGRRAALFGILDELGGQAFMTGTDRALFDALAGDAQFFNVSAGQLTGI",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPMFVVNTNVPRASVPDGLLSELTQQLAQATGKPAQYIAVHVVPDQLMTFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLTERLRISPDRIYINFCDMNAANVGWNGSTFA",
    "output": "Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSVLLFGVSHRSAPVVVLEQLSIDESDQVKIIDRVLASPLVTEAMVLSTCNRVEVYAVVDAFHGGLSVIGQVLAEHSGMSMGELTKYAYVRYSEAAVEHLFAVASGLDSAVIGEQQVLGQVRRAYAVAESNRTVGRVLHELAQRALSVGKRVHSETAIDAAGASVVSVALGMAERKLGSLAGTTAVVIGAGAMGALSAVHLTRAGVGHIQVLNRSLSRAQRLARRIRESGVPAEALALDRLANVLADADVVVSCTGAVRPVVSLADVHHALAAARRDEATRPLVICDLGMPRDVDPAVARLPCVWVVDVDSVQHEPSAHAAAADVEAARHIVAAEVASYLVGQRMAEVTPTVTALRQRAAEVVEAELLRLDNRLPGLQSVQREEVARTVRRVVDKLLHAPTVRIKQLASAPGGDSYAEALRELFELDQTAVDAVATAGELPVVPSGFDAESRRGGGDMQSSPKRSPSN",
    "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTEALVVDDSHFMRTVISDILEDGGVDVVGTAENGARALDAVTDVQPDVITMDVEMPEMDGIEATAEIMREQPTPILMVSALTTEDADATLEAMEKGAIDTFAKPGGTISTELSGHSEELVAAVERVASADPTAGHDVEMEPASPPDATTSEYADNPTLLIGASTGGPNVVESILASLPAEADFRVLIVQHMPDQFTSRFADRLDAASQYDITEAEDGSRIGGGEGLVARGDYHMRVSGYSNGRLRVRLDQSERLHSVRPAIDVTFKSAAERVTDPLVSVVLTGMGSDGADGVRAVKDAGGATLAQNEATSAVFGIPERAIETGCVDDVLPVDQLTEAIADSIRRTT",
    "output": "Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the Htr transducer proteins (methyl-accepting chemotaxis proteins) by CheR. Also required for Htr deamidations, at least at a specific glutamine-glutamate pair in HTR-II and a specific aspartate-glutamine pair in Htr4."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLERIKDSFTESIQTKIDAAEALPESIAKAAEMMVHCLLGGNKILACGNGGSAGDAQHFSAELLNRYEIERPPLPAIALSTDTSTITAIANDYSYDEIFSKQIFALGQPGDILLAISTSGNSGNVIKAMEAALSRDMTIVALTGKDGGAMAGLLSVGDVEIRVPSNVTARIQEVHLLVIHCLCDNIDRTLFPQDEQQ",
    "output": "Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIISIHESPQPLLQDITYLRISVSDTPEVPIKKHFKECVHFIHSCRLNGGNCLVHCFAGISRSTTIVIAYVMTVTGLGWQEVLEAIKASRPIANPNPGFRQQLEEFGWANSQKLRRQLEERFGEIPFRDEEDLRALLPLCRRCRQGSATSAASATTASSAAEGTLQRLVPRSPRDSHQPLPLLARVKQTFFCLPRCLSRKGGK",
    "output": "May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6 (By similarity).; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQTHVLFEHPLNEKMRTWLRIEFLIQQMKALLPVSDHASALHFFRNVGDLLDVFERGDTRTELLKELERQQRKLQSWAEVPGVDNERIESLRHELKARSSMLMAAPRLGQTLREDRLIALVRQRLSIPGGCCSFDLPLLHVWLCSPQEERDVQVNSWLATLQPLTYTLDMILDLIRQSAPFRKQTSLNGFYQDNGDDADLLRLQLPLQEALYPQISGHKSRFAIRFMPLDSEHGRVPERFDFELACC",
    "output": "Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGPFKFGLWGVALYGVLPSQIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNNSTPAVQTLSPGVTNNTDKDVRPAGFTQGGNTRDAVIRFPKDSGHNAVYVSVSDVLSPDQVKQRQDEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNSRKSELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKSDADAALSSAMESRKKKEDKKRSAENNLNDEKNKPRKGFKDYGHDYHPAPKTENIKGLGDLKPGIPKTPKQNGGGKRKRWTGDKGRKIYEWDSQHGELEGYRASDGQHLGSFDPKTGNQLKGPDPKRNIKKYL",
    "output": "Inactivates ribosomes by hydrolyzing 16S RNA in 30S ribosomes at a specific site.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQIINDPAEMQKIAEKLRLQHQYIGVVMTMGALHEGHLSLVKLAKAHAGTVIMTIFVNPTQFGPNEDFYRYPRPFEQDAALARSAGVDYLFAPSTEAMYPDGYSTSIDPGPIATRFEGASRPGHFGGMVTVVVKLLGITRPHLAVFGEKDAQQLAIIRRVVTDLNIGTTILGAPIVRESDGLATSSRNIYLSSNERQQATVLYRAIRYAKMEIDKDRTDLEAIAGEAEALVRSEPDAEPDYLCFVDDATFEPVTQAVTGKAYRLIMAVRIGSTRLIDNWRFDYQ",
    "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGTAEESDKAEAVSVPETVSGSVESQDKEHNSTSSSSDSTDVVGGKKRTIDEVDGSSENNSASVDQLKDAPTDSKPKTEATEDSPIRGNQGNNQENSQENKDDEDDEDDNDDDDNDDDDDEDEDVESYRKKQRRERNRFLDIEAEVSEDEDDEEDEEDSELVREGFITRGDEEDEEDRGGRVDDRLHRELDQNLQKTADEDMHKIAEDFKKRYGRDSSKDYRVQTQGGYVPQRFMLPSVDTAIIWSVRCRPGKEKELVRKLLNKKFNLDKSMGSKKLKILSIFQRDNYTGRIYIEAPKQSVIEKFVNGVPDVYSNQKLLIPVQELPLLLKPTKSDEVRLDVGSYVRIKRGIYKNDLAVIDQISQNNLEALLKIVPRLDYGKNDEIDPDTNQRKAKRATFASRPPPQLFNPTMALRLDQANLFKRDDRHFTYRKEDYVDGYLFKSFKIQYLDTKNIQPTVEELSRFGSKEGDVDLAAIAQTMKKAQASKAMFQPGDRVEVLTGEQRGSRGVVTRSSKDVISVKLSGFSDKSLEFPIASLRKIFELGDHVTVIAGEHEGNAGLVLLVQNGQVTFVSDQTRENLTISANNLSKSMDSTPTSSEYALHDIVELSAKNVACVIQAGHDIFKIIDDSGKVATVTKGSILAKINVARAKVAAVDGNGREIKIGDVVREKIGSRREGQVLYVQNQHIFIRSKTITENAGVFVVNPMNVEAVASKENLMSSALDLSKINPNIASKMGPPQTTQQTRLVGRDVALNKTVRIRSAGYKGQLGIVKDVNGDKATIELHSKNKHITIDKRKLTYFSHEGGEGITYDELVSRRGRTPHTRLGPSYVSAPRHMAAGGAVATNTPQQLPGGMTPGWNAFDGGKTPAVGQNGGTSSWGGASTWGGQGPGGASAWGGAAGNTSTWGGQGATSTWGGASTWGNKSSYGGASSWAASGESGAASAWGGGNKSSYGGTSTWGGNQGGVSAWGGSGNKSQRSKNTGGSSTWGNNQSQHNSGERSAWGNASQHNNSGNRSAWGNQDARGGGSTWGGNN",
    "output": "The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGMVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKSKQTVTE",
    "output": "The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKKTAIAIAVALAGFATVAQAAPKDNTWYAGAKLGWSQYHDTGFIHNDGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKSNVPGGPSTKDHDTGVSPVFAGGIEYAITPEIATRLEYQWTNNIGDANTIGTRPDNGLLSVGVSYRFGQQEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKSTLKPEGQQALDQLYSQLSNLDPKDGSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISKGIPSDKISARGMGESNPVTGNTCDNVKPRAALIDCLAPDRRVEIEVKGVKDVVTQPQA",
    "output": "With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSKLFWAMLAFISRLPVPSRWSQGLDFEQYSRGIVMFPFIGLILGGVSGLIFILLQSWCGIPLAALFCILALALLTGGFHLDGLADTCDGIFSARRRERMLEIMRDSRLGTHGGLALIFVLLAKILVVSELALRGTPMLAALAAACAAGRGSAVLLMYHHRYARDEGLGNVFIGKVSGRQTCITLGLAVIVATVLLPGMQGLAAMVVTLAAIFILGQLLKRTLGGQTGDTLGAAIELGELIFLLALL",
    "output": "Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTGPTKISILGQESIVADFGLWRNYVAKDLISGCPSTTYVLITDTNIGSIYTPGFQKSFEEAAASVSPSPRLLIYNAPPGEVSKSRQTKADIEDWMLSQSPPCGRDTVVIALGGGVIGDLTGFVAATYMRGVRFVQVPTTLLAMVDSSIGGKTAIDTPLGKNLIGAIWQPSRIYIDLEFLETLPVREFINGMAEVIKTAAISSEEEFTALEDNAETILSAVRREVKPGQRRFEGIEEILKARILASARHKAFVVSADEREGGLRNLLNWGHSIGHAIEAILTPQILHGECVAIGMVKEAELARHLGILKGVAVARIVKCIAAYGLPTSLKDSRIRKLTAGKHCSVDQILFNMALDKKNDGPKKKIVLLSAIGRTYEPRASVVPNEDIGVVLAPSIEVHPGVSTTSEVVCAPPGSKSISNRALVLAALGSGTVRIKNLLHSDDTEVMLNALERLGAATFSWEEEGEVLVVNGKGGALQAHPSPLYLGNAGTASRFLTTVATLATASSVDSSVLTGNNRMKQRPIGDLVDALTANGAQIEYVENKGSLPLKIAASGGFTGGQINLAAKVSSQYVSSLLMCAPYAKEPVTLKLVGGKPISQPYIDMTTAMMRSFGIDVKKSTTEEHTYHIPQGRYINPAEYVVESDASSATYPLAIAAVTGTTCTIPNIGSKSLQGDARFAVDVLRPMGCTVEQTDTSTTVTGPADGVLRPLPNVDMEPMTDAFLGASVLAAIARGKDSNHTTRIYGIANQRVKECNRIKAMHDELAKFGVVCREHDDGLEIDGIDRSTLRQPAGGVFCYDDHRVAFSFSVLSLIAPKPTLILEKECVGKTWPGWWDTLRQKFAVKLEGKELKEAESPVLTRAEKASASVFIIGMRGAGKTTSGHWVASTLKRPFIDLDDELERIEGMTIPDIIKQRGWQGFRDAELNLLQRTMKERPTGHVFACGGGVVEIPEARKLLIDWHKTKGNVLLIMRDIKQVMAFLNIDKTRPAYVEDMLGVWLRRKPWFQECSNIQYYSQHASAGLPRASEDFARFIKFVTGLEDSLGTIKKKQHSFFVSLTLPDVRGADQILEQACVGSDAVELRVDLLEDPDSSNGIPTVDFVADQISYLRSRITLPVIFTIRTKGQGGRFPDDAHAEAMQLYRLAVRSGCEFVDLEIAFPDEMLRAVTEMKGYSKIIASHHDPNGELSWANMSWMKYYNRALEYGDVIKLVGVARNLDDNTALRKFKNWAEEAHDVPLIAINMGGNGQLSRILNGFMTPVSHPALPFRAAPGQLSATDIRKGLSLMGEIKKKRFALFGSPISESRSPALHNTLFAEMGLPHEYTRLETANVEDVKDFIRAPDFGGASVTIPLKLDIMPLLDEITAEAEIIGAVNTVVPVSDGEGKPQRLVGHNTDWQGMVQCLRNAGAYGADGSASALVVGGGGTSRAAIYALHQMGFSPIYIVGRNPAKLESMVSTFPTSYNIQIVEGNEKLEHVPHVAIGTIPADRPIDPGMREILCHMFERAQEADADASRTIEGSPRVLLEMAYKPRVTALMQLAVDAGWTTIPGLEALIGQGVHQVGLIDLLQMDITDGVQFQHWTGIRPLYERARVCCDILLSGRTMLTCS",
    "output": "The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MADQRMDISSTISDFMSPGPTDLLSGSLSTSGVDCNRKRKGSATDYQESMDTDKDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTSLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFASTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDSEPDNEGCNLSCLVAIGRLHSHMVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSAGLLPGQAQETPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL",
    "output": "Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers'). The predominant Zeitgeber for the central clock is light, which is sensed by retina and signals directly to the SCN. The central clock entrains the peripheral clocks through neuronal and hormonal signals, body temperature and feeding-related cues, aligning all clocks with the external light/dark cycle. Circadian rhythms allow an organism to achieve temporal homeostasis with its environment at the molecular level by regulating gene expression to create a peak of protein expression once every 24 hours to control when a particular physiological process is most active with respect to the solar day. Transcription and translation of core clock components (CLOCK, NPAS2, BMAL1, BMAL2, PER1, PER2, PER3, CRY1 and CRY2) plays a critical role in rhythm generation, whereas delays imposed by post-translational modifications (PTMs) are important for determining the period (tau) of the rhythms (tau refers to the period of a rhythm and is the length, in time, of one complete cycle). A diurnal rhythm is synchronized with the day/night cycle, while the ultradian and infradian rhythms have a period shorter and longer than 24 hours, respectively. Disruptions in the circadian rhythms contribute to the pathology of cardiovascular diseases, cancer, metabolic syndromes and aging. A transcription/translation feedback loop (TTFL) forms the core of the molecular circadian clock mechanism. Transcription factors, CLOCK or NPAS2 and BMAL1 or BMAL2, form the positive limb of the feedback loop, act in the form of a heterodimer and activate the transcription of core clock genes and clock-controlled genes (involved in key metabolic processes), harboring E-box elements (5'-CACGTG-3') within their promoters. The core clock genes: PER1/2/3 and CRY1/2 which are transcriptional repressors form the negative limb of the feedback loop and interact with the CLOCK|NPAS2-BMAL1|BMAL2 heterodimer inhibiting its activity and thereby negatively regulating their own expression. This heterodimer also activates nuclear receptors NR1D1/2 and RORA/B/G, which form a second feedback loop and which activate and repress BMAL1 transcription, respectively. BMAL1 positively regulates myogenesis and negatively regulates adipogenesis via the transcriptional control of the genes of the canonical Wnt signaling pathway. Plays a role in normal pancreatic beta-cell function; regulates glucose-stimulated insulin secretion via the regulation of antioxidant genes NFE2L2/NRF2 and its targets SESN2, PRDX3, CCLC and CCLM. Negatively regulates the mTORC1 signaling pathway; regulates the expression of MTOR and DEPTOR. Controls diurnal oscillations of Ly6C inflammatory monocytes; rhythmic recruitment of the PRC2 complex imparts diurnal variation to chemokine expression that is necessary to sustain Ly6C monocyte rhythms. Regulates the expression of HSD3B2, STAR, PTGS2, CYP11A1, CYP19A1 and LHCGR in the ovary and also the genes involved in hair growth. Plays an important role in adult hippocampal neurogenesis by regulating the timely entry of neural stem/progenitor cells (NSPCs) into the cell cycle and the number of cell divisions that take place prior to cell-cycle exit. Regulates the circadian expression of CIART and KLF11. The CLOCK-BMAL1 heterodimer regulates the circadian expression of SERPINE1/PAI1, VWF, B3, CCRN4L/NOC, NAMPT, DBP, MYOD1, PPARGC1A, PPARGC1B, SIRT1, GYS2, F7, NGFR, GNRHR, BHLHE40/DEC1, ATF4, MTA1, KLF10 and also genes implicated in glucose and lipid metabolism. Promotes rhythmic chromatin opening, regulating the DNA accessibility of other transcription factors. May play a role in spermatogenesis; contributes to the chromatoid body assembly and physiology. The NPAS2-BMAL1 heterodimer positively regulates the expression of MAOA, F7 and LDHA and modulates the circadian rhythm of daytime contrast sensitivity by regulating the rhythmic expression of adenylate cyclase type 1 (ADCY1) in the retina. The preferred binding motif for the CLOCK-BMAL1 heterodimer is 5'-CACGTGA-3', which contains a flanking Ala residue in addition to the canonical 6-nucleotide E-box sequence (By similarity). CLOCK specifically binds to the half-site 5'-CAC-3', while BMAL1 binds to the half-site 5'-GTGA-3' (By similarity). The CLOCK-BMAL1 heterodimer also recognizes the non-canonical E-box motifs 5'-AACGTGA-3' and 5'-CATGTGA-3'. Essential for the rhythmic interaction of CLOCK with ASS1 and plays a critical role in positively regulating CLOCK-mediated acetylation of ASS1 (By similarity). Plays a role in protecting against lethal sepsis by limiting the expression of immune checkpoint protein CD274 in macrophages in a PKM2-dependent manner (By similarity). Regulates the diurnal rhythms of skeletal muscle metabolism via transcriptional activation of genes promoting triglyceride synthesis (DGAT2) and metabolic efficiency (COQ10B) (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK",
    "output": "Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development . Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation . Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes (By similarity). Required for normal neural stem cell proliferation in the hippocampus dentate gyrus (By similarity). Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation (By similarity). Promotes formation of synapses via its interaction with FZD5 (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MILYEYPFNERIRTLLRLEDLFERFTFFVAQEDAREHHVALTTLFEISEVAGRADLKSDLMKELERQRQTLAPFRGNPGIEQNALEAVLGEIEQTLANLAQMQGKTGQHLIDNEWLASIRSRAVIPGGTCKFDLPSYYAWQQWPAEQRRHDIAKWAMPLLPLRDAAMIVLRLARESGQASKVMAMQGSYQQMLSGRTYQLMQVRVPPELRVIPEASANKYMLWVRFTAQDGDVRPRAVDIDVPFQLTLCNL",
    "output": "Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAGPGEYFAIGAYVSCRTCQETRLQGEVVAFDYPSKMLALKCPSSSGKANHADILLLNLDYVSDVEVINERTQTPPPLASLNITKLASRARLEKEEKLSQAYAISAGVSLDGQQLFQTIHKTIKDCKWQEKNIVVMDEVVISPPYQVENCKGKEGRALTHVCKIVEKHFRDVENQKGVQRNPVAQSQKETSTSS",
    "output": "Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPKRGKRAAAEDGEEPKSEPETKKSKGAAKKTEKEAAGEGPVLYEDPPDQKTSASGKSATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLTHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEFESFILVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKDLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGEMLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL",
    "output": "Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 are DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. Does also incise at AP sites in the DNA strand of DNA/RNA hybrids, single-stranded DNA regions of R-loop structures, and single-stranded RNA molecules. Has a 3'-5' exoribonuclease activity on mismatched deoxyribonucleotides at the 3' termini of nicked or gapped DNA molecules during short-patch BER. Possesses a DNA 3' phosphodiesterase activity capable of removing lesions (such as phosphoglycolate) blocking the 3' side of DNA strand breaks. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Acts as a loading factor for POLB onto non-incised AP sites in DNA and stimulates the 5'-terminal deoxyribose 5'-phosphate (dRp) excision activity of POLB. Plays a role in the protection from granzymes-mediated cellular repair leading to cell death. Also involved in the DNA cleavage step of class switch recombination (CSR). On the other hand, APEX1 also exerts reversible nuclear redox activity to regulate DNA binding affinity and transcriptional activity of transcriptional factors by controlling the redox status of their DNA-binding domain, such as the FOS/JUN AP-1 complex after exposure to IR. Involved in calcium-dependent down-regulation of parathyroid hormone (PTH) expression by binding to negative calcium response elements (nCaREs). Together with HNRNPL or the dimer XRCC5/XRCC6, associates with nCaRE, acting as an activator of transcriptional repression. Stimulates the YBX1-mediated MDR1 promoter activity, when acetylated at Lys-6, leading to drug resistance. Acts also as an endoribonuclease involved in the control of single-stranded RNA metabolism. Plays a role in regulating MYC mRNA turnover by preferentially cleaving in between UA and CA dinucleotides of the MYC coding region determinant (CRD). In association with NMD1, plays a role in the rRNA quality control process during cell cycle progression. Associates, together with YBX1, on the MDR1 promoter. Together with NPM1, associates with rRNA. Binds DNA and RNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAEAQKTVRTLTGRVVSDKMDKTITVLIERRVKHPIYGKYVKRSTKLHAHDETNQCKIGDKVSIRETRPQSKTKSWALVEVVERAVEV",
    "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKPDAHQVKQFLLNLQDTICQQLSAVDGAEFVEDSWQREAGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVYPRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV",
    "output": "Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTAGSDLDDFRGLLAKAFDERVVAWTAEAEAQERFPRQLIEHLGVCGVFDAKWATDARPDVGKLVELAFALGQLASAGIGVGVSLHDSAIAILRRFGKSDYLRDICDQAIRGAAVLCIGASEESGGSDLQIVETEIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNVAVVAVPAAQVSVQTPYRKVGAGPLDTAAVCIDTWVPADALVARAGTGLAAISWGLAHERMSIAGQIAASCQRAIGITLARMMSRRQFGQTLFEHQALRLRMADLQARVDLLRYALHGIAEQGRLELRTAAAVKVTAARLGEEVISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVAAGMTPDHDGYAAVVGASKA",
    "output": "Catalyzes the dehydrogenation at the alpha-beta position of ACP-bound acyl chains. This results in the introduction of a double bond in the lipidic chain, which is further transferred to the epsilon-amino group of lysine residue in the mycobactin core by MbtK (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTEDNKKQRLIWIDLEMTGLEPDENHIIEVATIVTDAQLNTLAEGPVIAVHQPQKHLDRMDDWNVKTHTGSGLVERVKESQHDERKAAAETIEFLRQYIDAGVSPMCGNSICQDRRFLAKHMPELEAFFHYRNLDVSTLKELAKRWNPEVANSFKKSGAHEALADIRESIAELQHYREHFFSK",
    "output": "3'-to-5' exoribonuclease specific for small oligoribonucleotides."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKEHFNRSKPHVNVGTIGHVDHGKTTLTAAITTVLAKRGLSELRSFDSIDNAPEEKERGITINTSHVEYQTANRHYAHVDCPGHADYVKNMVAGAAQMDGAIIVVAATDGPMPQTREHILLARQVNVPRLVVFMNKCDMVDDEEMLELVEMDMRELLSFYDFDGDNTPIIRGSALGALNGEPQWEDKVMELMEAVDNWVPLPERDIDKPFLMPVEDVFSITGRGTVATGRIETGIVKTGDEVQIIGLGAEGMKSVVTGVEMFRKILDEGQAGDNVGLLLRGIDKDQIKRGMVISHPGKITPHKRFKAEVYILKKEEGGRHTPFHNKYRPQFYIRTLDVTGEITLPEGTEMVMPGDNVTITVELIYPVACNVGLRFAIREGGRTVGAGQITELID",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKASVYDFTLKELSQLLKPSFRAKQLYLWLYAKYKTSFKDMQNNFSKDFIAYLEREFTLRTIEIAHVRKSIDGSKKYLFKSLRDNHTFEAVLLKMKDKKIDEETNAILEGEKYTVCVSCQIGCQVGCTFCFTQKGGFVRNLKASEIIQQALLIKEDNNLPIEKALNIVFMGMGEPLNNLDEVCKAIEIFNTGMQISPKRITISTSGVADKIPILAGKNLGVQLAISLHAVDDKTRSSLMPLNKKYNIECVLNEVRKWPLEQRKRVMFEYLLIKDLNDSLDCAKKLLKLLNGIKSKVNLILFNPHEGSKFERPSLESARMFADFLNSKGLLCTIRESKALDIEAACGQLREKKLSQQI",
    "output": "Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATGRRKANRTKKEETNWQERVIQIRRVSKVVKGGKKLSFRAIVVVGNERGQVGVGVGKASDVIGAVKKGVADGKKHLIDIPITKSNSIPHPIDGVGGGAKVMMRPAAPGTGVIAGGAVRTVLELAGVRNVLAKQLGSNNPLNNARAAVNALSTLRTLAEVAEDRGIAIEKLYI",
    "output": "With S4 and S12 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLKEFKTFIARGNVIDMAVGIIVGAAFTSIVKSLVNNLINPLIGLFIGRIDLSNLVLTVGDAQFKYGSFLNAVINFLIISFVVFLMVKAINTFRKKEDKKTEAPSEEVMYLKEITELLKKNKE",
    "output": "Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIIEEIQGNIANLSQDEKQKHVEKVYLENSDLVKRIQRVKTDHGNEIGIRLKQPIDLQYGDILYQDDTNMIIVDVNSEDLLVIKPRNLKEMGDIAHQLGNRHLPAQFTETEMLIQYDYLVEDLLKELGIPYSHEDRKVNQAFRHIGHSHD",
    "output": "Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKTLLLTLVVVTIVCLDLGYTLTCVTTKSIGGVTTEDCPAGQNVCFKRWHYVTPKNYDIIKGCAATCPKVDNNDPIRCCGTDKCND",
    "output": "Binds irreversibly to M1 (CHRM1) muscarinic acetylcholine receptors, and reveals a slightly weaker effect on M3 (CHRM3) receptors. The mechanism of toxin-receptor interaction comprises at least two steps. The first step is fast with no competition between the toxin and the antagonist. The second step is slow with formation of a more stable toxin-receptor complex and inhibition of the antagonist binding."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNNLSYLEPDYSEFVEVDPTGRYGRYNEVLGKGASKTVYRAFDEYEGIEVAWNQVKLYDFLQSPEDLERLYCEIHLLKTLKHKNIMKFYTSWVDTANRNINFVTELFTSGTLRQYRLRHKRVNIRAMKHWCRQILRGLHYLHSHDPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAAILRKSHAAHCVGTPEFMAPEVYEEAYNELVDIYSFGMCILEMVTFDYPYSECTHPAQIYKKVMSGKKPDALYKVKDPEVKCFIEKCLATVSLRVSARELLDDPFLRIDDGEFDLRSVDMEDSVGPLYRQPHHLPDYYNYPSNSSSLNRQYSNGNYPSNSSSLNRQYSNGYNSHHEYQNGWAYNPAETEETHGIELFESRNNDDQEEEKKSGNVDITIKGKRRDDGGLFLRLRIADKEGRVRNIYFPFDIETDTALSVATEMVAELDMDDHGVTKIANMIDGEISSLVPSWRPGPEFEECLAAAAAANAASICNNCVSNRTSMGSVMDFLRTNPGANVIQCCRNGCGETHGRFEEITIRETEVRLRELWKLQQQQESRELSSIDSGHNHSEEEEEEEVLYEDPENMFSCEAGNEINHISGSGSFSFMPSKYCDEPSEKTENQVQQELRWLKAKCQIELRDIQDEQLKTRWPESGEEVEISPKDGFLGSVSGLGREEDTVKEMFGERLVPKCLKRTTSLPVDAIDS",
    "output": "Regulates flowering time by modulating the photoperiod pathway. Phosphorylates APRR3."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTHSNRMLLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVVVLKDVLQTRMNFEMGVTEEMMAFAEKIRPAHICLVPETRQELTTEGGLDVAGQEARIKAAVERLARTGAEVSLFIDADERQIEASRRVGAPAIELHTGRYADAQTPTEVAEELKRIVDGVAFGVGQGLIVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKALIVAASR",
    "output": "Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLWAIPELGSPCPISISYEMSDSQDPTTSPVVTTQVELGGCSRQGGGNGFLRFRQHQEVQAFLSLLEDSFVQEFLSKDPCFQISDKYLLAMVLVYFQRAHLKLSEYTHSSLFLALYLANDMEEDLEGPKCEIFPWALGKDWCLRVGKFLHQRDKLWARMGFRAVVSRQCCEEVMAKEPFHWAWTRDRRPHHGGVQRVCPQVPVRLPRGPGLSPPHCSPCGLPQHCSSHLLKPVSSKCPSLTSECHRPPSQNYLSRVKNAWGGDFLIVLPPQMQLEPGTYSLRIFPKPPARPGH",
    "output": "Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correct localization of the active form of Aurora B in prometaphase."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGKLLLILGSAIALPSFAAAGGDLDISDTVGVSFWLVTAGMLAATVFFFVERDQVSAKWKTSLTVSGLITGIAFWHYLYMRGVWIDTGDTPTVFRYIDWLLTVPLQVVEFYLILAACTSVAASLFKKLLAGSLVMLGAGFAGEAGLAPVLPAFIIGMAGWLYMIYELYMGEGKAAVSTASPAVNSAYNAMMMIIVVGWAIYPAGYAAGYLMGGEGVYASNLNLIYNLADFVNKILFGLIIWNVAVKESSNA",
    "output": "Light-driven proton pump. May have a regulatory rather than energy harvesting function, based on light-induced opening of proton channels, to modulate cell physiology depending on light intensity variations. Could be, therefore, a sensory rhodopsin, potentially associated with a transducer component."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTIALGKFTKDEKDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFAVGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL",
    "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAGNKGRGRAAYTFNIEAVGFSRGEKLPDVVLKPPPLFPDTDYKPVPLKTGEDEDYMLALKQELRETVKRLPYFIEPPEEKQDDIERYSKRYMKVYKEEWVPDWRRLPREMMPRKKCKKGDPKSKPSKAAAKATSLINSADVLKTIEELEKRGEGERSDEENEEKEGSKEKDKDDEEDGEEDAEQEDYDEEEQEEENDYINSYFDNGDDFGVDSDDNMDEATY",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the RPC3/POLR3C-RPC6/POLR3F-RPC7/POLR3G subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMIKQYLQVTKPGIIFGNLISVVGGFLLASKGVIDYPLFLATLFGVSLVVASGCVFNNYIDRDIDRIMERTKNRVLVKGLIDPKVSLIYASILGIAGMLLLYVGANPLAMWLAVIGFVIYVGVYSLYMKRKSVYGTLIGSLSGAAPPVIGYCAVTGQFDMGALILLLIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVIKGISVTKNHITLYILAFMVATLMLTLSGYAGYKYLVVAAAVSVWWLGMALRGYKATNDSVWARKLFVFSIIAITSLSVMMSVDFNVPSSAGLLTYVG",
    "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNATSLLQLMWLASPALPIGGFSYSEGLEAAVDTARVATEEEASEWLLDQLDLSLTRSDLAVLAQSMPAWQCGDTARISQLNAWVLQTRESNELRAQTEQMGRSLLEWLRNHTTATAEQIELLANLQPTYPLAFALAASATQAPLRDCLLAYAFGWAENMVQAAIKSVPLGQSAGQRILQALAAQIPCAVDHALTLPDDARQAFSPMLAILSARHEVQYSRLFRS",
    "output": "Required for maturation of urease via the functional incorporation of the urease nickel metallocenter."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPAARGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA",
    "output": "DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNKKQRDAKNKKRFQQQNPLFKRKKFCRFTVAGVEQIDYKDLDTLKDFIGENGKITPARLTGTRSHYQRQLDTAIKRARFLALMPYTDQHKH",
    "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDNEKVTDTNPKEPSNVESIITTSEVTPSPPPSTTTSTTTNATTTITTSQPQANIIGGKRSRKDDEIISIQEALNDQLEEEKNLLEEAKEQEQEDWGDESICTFDKGYINQSVFACKTCQLSNDKLFGFCYGCSMHCHLYHDVYELFNKRNFRCDCGTKIQEPNNSFKCQLSGILKEDDNNNVNNINNSNNTTTTTTTTTTTTTTTNNNHLNDIDIGSYDKSQILNERNHYNHNFKGKYCYCDSPYDYKEDMIQCIFCEDWFHENCLKLNSNVTDIPSPGEFSDLICADCLSKNQFLLLYPQIRCYIENDHIIIGDNNNNNNNSNNSNSICKVEGGVITPNKKYDLFCKELWKDELCSCLKCKEIYKDKKVEFLFEKDENSLKKKNKTVDENLDNKPVNVFEMGQDVFSKTLPPTQQRALIEGFSDMKEKLKELFSKKLDKNQVITKQDIQSFFVDLNVNKKFKK",
    "output": "Putative E3 ubiquitin-protein ligase."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDKLADLNYTLSVITLMNDTLHSIIQDPGMAYFPYIASVLTVLFTLHKASIPTMKIALKTSKCSYKVIKYCIVTIINTLLKLAGYKEQVTTKDEIEQQMDRIVKEMRRQLEMIDKLTTREIEQVELLKRIHDNLITRPVDVIDMSKEFNQKNIKTLDEWESGKNPYEPSEVTASM",
    "output": "Plays an essential role in the virus replication cycle by acting as a viroporin. Creates a pore in the host reticulum endoplasmic and as a consequence releases Ca(2+) in the cytoplasm of infected cell. In turn, high levels of cytoplasmic calcium trigger membrane trafficking and transport of viral ER-associated proteins to viroplasms, sites of viral genome replication and immature particle assembly.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSVRKILRMGDPILRKISEPVTEDEIQTKEFKKLIRDMFDTMRHAEGVGLAAPQIGILKQIVVVGSEDNERYPGTPDVPERIILNPVITPLTKDTSGFWEGCLSVPGMRGYVERPNQIRMQWMDEKGNQFDETIDGYKAIVYQHECDHLQGILYVDRLKDTKLFGFNETLDSSHNVLD",
    "output": "Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNQKTLEKIEFPDIINKLWQKAESFPGKQLALKVRPLSDSKIIEEKLLEVEEGLSYLRFKTVDLSVLSDFSEIFLKLSKESMLTGQEIYRLGQLLKVSKDTFFEISRGAFPRLKQIVKLLFFDEALVKDIERSFWPEGTVKDEASPELKRIRGQIARLKDKMREAVEKYLKEPELAKYLQEPLISVRGDRFVLPVKASYKSQVPGIIHDRSNTGQTLFIEPYSAVEAGNELKTLELQEKEIIEKILKDFTQRLACNLTEIKRTYELLGEIDLIVAKARLALELDAYKPRISENGVLSFKQARHPLLGKKAVPFDLTLGKEFDLLIITGPNTGGKTVTLKTIGILTIMARAGLFIPASPETEIGLFGEVYVDIGDEQSIVQSLSTFSSHLLNLKFILENAREGDLVLLDELGTGTDPREGAALAKAILEELRGKKVKVVATTHTSELAAYAIETERVENASVEFDPESLKPTYRLHIGKPGRSNALYIAQGLGLKEQIIEKAKSFLKEEELKLDKLIFDVEQEKRQLEKAKEEVANLLISLKEKEAKLNDELENLEKTKEEIIRKYREKYQQKLLEIERKGKLVIEEIKEKIKTYEEKNLAKLLEEARQKTKEFSQNFALPFEPIKPYRPKVGETVELVEVGQKAEVLAVGENYAIVQAGIMKLNVSFDQIRPAQKQEKENEKGQVKKAGLELTKKQNFNLELDIRGMNTLEAEPVVEKYLDNAYLAGVEKVRIIHGKGTGALKKFLWDYLREVPFVKKFNFAPQNQGGDGATEVYLK",
    "output": "Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDDPDCDSTWEEESEEDGEDGQADDTTDEDTGDDDGDAEEARPSLFQSRMTGYRNWRAMQDMQRYRHNYPDLTDQDCNGDMCNLSFYKNEICFQPNGALIEDILQNWKDNYDLLEENHSYIQWLFPLREPGVNWHAKPLTLKEVEAFKSSKEVRERLVRAYELMLGFYGFHLEDRGTGAVCRAQNFQPRFHNLNSHSHNNLRITRILKSLGELGLEHYQAPLVRFFLEETLVQHKLPSVRQSALDYFLFAVRCRHQRRELVYFAWEHFKPRREFVWGPRDKLRRFKPQTIPQPLTGPGQADKDEGSRDPSQEAGTQGRTCGSGRDLSGDSGTAEDPSLLNTKPSDGGTLDGNQRDEAKSLSPKESKKRKLEGNRQEQVPGEADPQGVSEVEKIALNLEECALSPISQEPREAEPPCPVARVANEVRKRRKVEEGAEGDGVVSNTQMQASALPPTPSECPEAQKDGNGPEDSNSQVGAEDSKSQVGPEDPNSQVGLEDPNSQVGPEDPNSQVGPEDPNSQVGPEDPNSQVGPEDPNSQVVGPEQAASKSPVEDPDSDTMGTSVDESEELARIEASAEPPKP",
    "output": "Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MALLDFFLSRKKSTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEESK",
    "output": "Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL",
    "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARPVNFHPDSEQS",
    "output": "RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIVTETIIRFENVTKQFDNDPPVLDNVSFEIEKGKFYTLLGPSGCGKTTILRLIAGFLEASEGQIYLGDKVINQIPANKRPVNTVFQDYALFPHLNVYENVAFGLRIKKLKKDAIDKKVQEALRFVNLKGYEKREISEMSGGQRQRVAIARAIVNEPEVILLDEPLSALDLKLRTEMQYELRDLQKRLGITFIFVTHDQEEALAMSDEIFVLNKGEIQQSGTPIDIYDEPINKFVADFIGESNIVNGKMIQDFEVEFVERRFECVDQGFRPNEVVEVVIRPEDLEITSAEKGKLQVTVDWMLFRGVHYEVGCIDIDGNEWLVHTTRKVRVGDKIGLAFEPEAIHVMRLGETEEEFDKRLDSYDEVQ",
    "output": "Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNKTYMANPQNVERKWYVVDAEGKTLGRLASKVAAILRGKHKPTFTPHVDCGDFVIIVNAEKIQVTGKKVTDKVYYRHSGYPGGQKATTFEQMIARRPERVLELAIKGMLPHNRLGRQMYRKLKVYAGPEHPHAAQKPEPLEV",
    "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "XEIYNKDGNK",
    "output": "This protein is present in the macrocyst primary wall which is produced by amoebae during the onset of sexual reproduction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSVIILQRASR",
    "output": "Multidrug efflux pump that functions probably as a Na(+)/drug antiporter."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MARTVNCVYLNKEADGLDFQLYPGDLGKRIFDNISKEAWGLWQKKQTMLINEKKLNMMNVDDRKFLEEQMTSFLFEGKEVEIEGFVPEKDQD",
    "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDVTVAETPAVKTPTKAPKAPKSKTTKEPKAKVAAAHPPFINMVTAAISSLKERKGSSKIAILKYITANYKVGDQLTKINSRLRAALNKGVASKALVQSVGNGASGRFRVAEKAAATKKPVAKKPVAKKAATGEKKAKKTTVAKKTGDKVKKAKSPKKIAKPAAKKVAKSPAKKAAPKKAPAKKAAAPKA",
    "output": "Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARVTVEDCLEHVKNRFELVMVATKRARQIAVRGDQPMVEWENDKPTVVALREIAEGYVTADILDED",
    "output": "Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQIGKYQLVRKLASGGMAEVFLAKAAGPRGFEKTLVLKRILPHLAEDAAFVEMFLGEARLAAQLEHPNIVQIFDFGEAEGSFFLAMEFIDGPNLRKLVKRAAEEALPPAFCAKVVAAAAEGLAYAHEFRDVETGEPLGLIHRDVSPDNILVSRQGAVKVVDFGIAKVAGQGHRTLTGVVKGKVAYMPPEQLQAKAMDRRVDVYALGVVLYELLTGKRPFDATTDVSVMQAILFESFIPVSARRPDVPVALQQVLDKALAKDRERRYADCRALQDDLERFVLSTGEPVGAYQIAQRIAQWVPEVAAAPAMTPSQGGSKGAVASQAKADARSASMVSPPVDSTSPTTPMPRSLVAPVEVPADSTSPTTPMPVAIGGVVQALEPRSSPQQDTLQSYPVVVKTPALRADASARGASRPRAQSRASGVKVQAPQARDEDVVAMAAASSPPSGGASPAPTTPEDADDAVHTRSTEYAATVPSGRPGGRIAGIVGAVVALLVGGAVTVMRGDDSEVSPVRVNPPPLTHLPREPAVPSQGGRNVPQEKPAANVNAGARDSNDGAQAKPQVSTDVSVVPQEPHVARDATTPEAGLPTVKDAPPENGGAASKEGSAVVAKREPAKASGDPEPNPSRVRERAPTQKVAAVAKGRLEFRIRPYAVVSLDGKVLGQTPFAAVEVPEGRHTVRLVNKELGKDVTRTVDVKAGQATVFKLNLEAE",
    "output": "Pkn5 and pkn6 may have reciprocal roles in growth and development. Pkn6 may be a transmembrane sensor of external signals for development."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTGIVEVIGREILDSRGNPTVEVDVILECGAKGRAAVPSGASTGSHEAVELRDEDKGRYLGKGVLKAVNNVNTEIREALLGMDALNQVEIDKVMLELDRTPNKGRLGANAILGVSLAVAKAAAEALGQPLYKYLGGVNSKELPLPMMNILNGGAHADSAVDLQEFMIQPVGAKSFREAMQMGAEVFHHLGKILKANGDSTNVGNEGGYAPSKIQGTEGALALISEAVKAAGYELGKDITFALDAASSEFCKEVNGKYEYHFKREGGVVRTTDEMIKWYEELINKYPIVSIEDGLGEDDWDGWVKLTKAIGDRVQIVGDDLFVTNTERLKKGIELGAGNSILIKLNQIGSLTETLDAIEMAKRAGYTAVVSHRSGETEDATIADVAVATNAGQIKTGSTSRTDRMAKYNQLLRIEEELGSVAQYNGRDVFYNIKK",
    "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGTVPPACFQQILSFCYTGKLTMAASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAMIEDASSEPQSPCNQLQPATAAYVTSPSVPIPLLTRVKHEAMEMPPASGPGLASKRPLETGPRDGVAVATGAAGTPGTAPLKLPRVSYYGVPSLATLIPSIQQVPYPPGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKATGNYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRSVMGASAASLPLDPEFPSAAPQVFEQRIYAERRSDAATIVALRTDAVNVDLSTSANPAFEANEEVDGGGSVIQEVAAPEQLPADGQSSPQAFEQGNTSSSRPQTPVATATRRPEGTYAGTL",
    "output": "Functions as a transcriptional repressor through its association with the NuRD complex. Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53 (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAIEAPSTNG",
    "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI",
    "output": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSSIKLIVGLANPGAEYAQTRHNAGAWYVDLLAERHNQSLKEESKFFGYTARLNLAGQDIRLLVPATFMNLSGKAVAAMASFYRILPEEILVAHDELDILPGMAKLKLGGGNGGHNGLKDIQNKLGNNPNFYRLRIGIGHPGDKSKVTGFVLGKPPASEQTLIDDAIDESIRCTEVLLNEGMTKAMNRLHAFKASA",
    "output": "The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTKQALDATIADMAGPFLASLGLELWGIELSYGGRTVVRLFVDGPEGVTIDQCAEVSRHVGLALEVEDVISSAYVLEVSSPGLERPFFRAEQMSPYVGRQIELTLIDPTPEWPGRRKFRGELLAVEGDTVVLRPEGAPAPEAEEAVLRTSWQGVRKANLIHVFPEPGHKPRR",
    "output": "Required for maturation of 30S ribosomal subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLTTTIIAGIISFILTILAMPFFIRFYQLKKINGQQMHEDVKQHLAKAGTPTMGGTVFLLVAALVTFICAFVLHITGGPAFGATLAILFIVLIYGTIGFLDDFLKIFKKINQGLTAWQKMALQLIGGLVFYLVHVKPSGTDSLNLFGFPLHLGVFYIIFILFWVVGFSNAVNLTDGIDGLASISVVISLLTYSVIAYVQNQFDVLLIIISMVGALLGFFVYNHKPAKVFMGDVGSLALGAMLAAISITLRQEWTLLIIGIVYVLETASVMLQVSYFKWTKKRKGEGQRIFRMTPFHHHLELGGLRLRESGKKWSEWQVDFFLWSIGLLGSLLILAILYL",
    "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFSLSFIVIAVIIVVALLILFSFVPIGLWISALAAGVHVGIGTLVGMRLRRVSPRKVIAPLIKAHKAGLALTTNQLESHYLAGGNVDRVVDANIAAQRADIDLPFERAAAIDLAGRDVLEAVQMSVNPKVIETPFIAGVAMNGIEVKAKARITVRANIARLVGGAGEETIIARVGEGIVSTIGSSKHHTEVLENPDNISKTVLSKGLDSGTAFEILSIDIADVDISKNIGADLQTEQALADKNIAQAKAEERRAMAVATEQEMKARVQEMHAKVVEAESEVPLAMAEALRSGNISVKDYYNLKNIEADTGMRNAINKRTDQSDDESPEH",
    "output": "Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIQFTKMHGLGNDFMVVDGVTQNVFFSPEQIRRLADRNFGIGFDQLLLVEPPYDPDLDFHYRIFNADGTEVEQCGNGARCFARFVRNKGLTNKSKIRVSTSSGKMTLRLERDGTVTVNMGVPILEPSQIPFKAKKPEKTYLLQTPMQTFLCGAASMGNPHCVLDVEDVASASVAEIGAMLTKHERFPRGVNVGFMQVVDSGHIKLRVYERGAAETLACGTGACAAVVVGQVQGKLGQQVRVDLPGGTLTINWEGEGKPLWMTGPAQHVYDGQIQL",
    "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNMAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEGLKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYISEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFILITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGSGSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKLRIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQIALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVASLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLVWLAEYLVKFYSGFNVFSYLTFRAIVSLLTALFISLWMGPHLIAWLQKLQIGQVVRNDGPESHFSKRGTPTMGGLMILFSITISVLMWAYPSNPYVWCVLFILIGYGIVGFIDDYRKVVRKNTKGLIARWKYFWQSIIALAAAFTMYSIGKDTSATELVVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFAAYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR",
    "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKKSQIVKWLKPKKYKVREYNRCRICGRPRGYIRKFGLCRLCFRELALKGELPGVRKASW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNRNPYSRYYVPGPSPWPFFVAISANGMAVGLILWLHRTPSFLLMGMSLVCMLLSTFSWWRDLIREGDIGFHTRFVIKSFRDCVALFILSEVMFFFTFFWTFFHNALSPSCELGMRWPPPGIRTPNPSSTSLFETGLLISSGLFVTQAHKSMRLKDYDVGPFIGLVVTIVCGTVFFLVQLREYYWNSYTIADSVYGSVFYLLTGFHGMHVVVGTIWLMVSLVRLWRGEFSSQRHFGFEACIWYWHFVDVVWVALWCLVYVWFGGW",
    "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MALFHNPEERPYKLPDLCRTLDTTLHDVTIDCVYCRRQLQRTEVYEFAFSDLCVVYRDGVPFAACQSCIKFYAKIRELRYYSESVYATTLETITNTKLYNLLIRCMSCLKPLCPAEKLRHLTTKRRLHKIAGNFTGQCRHCWTSKREDRRRIRQETQV",
    "output": "Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT). The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization. Other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis. E6 also inhibits immune response by interacting with host IRF3 and TYK2. These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEPRVGNKFRLGRKIGSGSFGEIYLGTNIHTNEELAIKLENVKTKHPQLLYESKLYRILQGGTGVPNVKWFGVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKSVLMLADQMINRVEFFHSKSFLHRDLKPDNFLMGLGRRANQVYIIDFGLAKKYRDSTTHQHIPYRENKNLTGTARYASMNTHLGIEQSRRDDLESLGYILMYFLKGSLPWQGLKAGTKKQKYERISEKKVSTSIEALCRGYPSEFASYFHYCRSLRFDDKPDYAYLKRIFRDLFIREGFQFDYVFDWTILKYQQSQLTAPPSRALNPAVGTSAALPPGISNIDRYTGEEEGRPHMESSRRRVSGALDNSGNISNQPTSSSARDSMIPSSSLFAQSAGSSRRVTAVSGSRDNFPGSEELLQRSRTGDVSRGVIPRNSPGEAGKSTRRHYESVVKGIDNLQVSDEHHPH",
    "output": "Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGVEYAWFNNVETKPGQGFPTDWENQEKYKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYEPFDFDYQNLHTAPEGSKSQPIARPRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKNFDNIQKAMYSQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCRGWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYDADAIERAASTENEKDLYQRQLDVFLDPNDPKVIEQAIKDGIPLSVIEAAQQSPVYKMAMEWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLANLLTAGDTKPVLRALKRMLAMRHYKRAETVDGKVDTRALEEVGLTEAQAQEMYRYLAIANYEDRFVVPSSHRELAREAFPEKNGCGFTFGDGCHGSDTKFNLFNSRRIDAIDVTSKTEPHP",
    "output": "The nitrate reductase enzyme complex allows E.coli to use nitrate as an electron acceptor during anaerobic growth. The beta chain is an electron transfer unit containing four cysteine clusters involved in the formation of iron-sulfur centers. Electrons are transferred from the gamma chain to the molybdenum cofactor of the alpha subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGIDQRPLAIAVMGPTASGKTATAIALARQLDGEIVSVDSALVYRHLDIGSAKPDAAERAQAPHHLLDLRDPWQTYSAAEFAADASRVVVDIVARGKMPILAGGTGLYFRALLQGLSPMPEADPAMRAALAAEAAERGWAALHAELAQIDPAAATRIHATDPQRIQRALEVYRLTGTPITEWQRRPGVAPLPVRTLKLILAPHDRAVLHQRIEARFDAMLAQGFLDEVRALRAMPEMAAVEAPLDLPAVRAVGYRQAWEYLDGEGDAARFRDKAIFATRQLAKRQLTWLRGELDARWFDPHIDQERLAGAVSTFVAR",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSDPVFFPFAGPISLGEVAALAGAALPAGLDGTLAVAGAAPLESAGPDDLAYMDNAKYAEALGRTRARACLVSPRFAARVPEGTAALVTPQPYRGFAQVLARLFPSAARPGSLFGATGVSPGSFVHPEARLEPGVVVDPGVVIGPGAEIGSGTVLAAGAVVGPGTRIGRGCAIGPGASLLHALVGNRVIVHGGARIGQDGFGFAMGAGGHLKVPQVGRVIIQDDVEIGANTTIDRGASRDTIVGEGTKIDNLVQIAHNVVIGRHCVIVAQVGISGSTTLEDYVVLGGQVGVVGHLRIGMGAQIAGSSNINKDVPPGARWGGTPAKPVREWFREMTTLKRLAARERGPEDTDG",
    "output": "Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA",
    "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLTPMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGVMAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFIGTSLSSFILKRSVKLALAGAPLILAVSALVLTLWGSDKIVATGVAIIWGLTFALVPVGWSTWITRSLADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVKMKKS",
    "output": "Involved in the efflux of purine ribonucleosides, such as inosine and guanosine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRFYRTYLLVAGAFCSLCTLAVIFNCGWDDSPPATPSAINGGGSNAPLISSPTNLPETFLYISILTSPNETERRQNVRDTWFRLSTKGPSVFIAKFAVGTMGLAAEDRRLLAEENEKFGDLALLDRHEESYERLAKKTLACFVHAFANFKFKFFLKTDIDSFVRITPLIINLKQIQDPMLYWGFLDGRAKPFRKGKWKEPEWNLCDRYLPYQLGGGYVLSYELIRFLAINAQLFRHYRNEDVSVGAWIGGLDVKYVHDPRFDTEWRSRGCNNEYLITHKHTEQEMQEMFENLKKTGKLCAKEFQKHPSYVYDFSKAPSECCTRVNGSNIP",
    "output": "Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Required for vulval morphogenesis and zygotic cytokinesis, suggesting that glycosaminoglycans play a central role in vulval morphogenesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTDRTQRELGWPEILNALAARCRLPAGRNRALALPFQPTAEAAREALALVGEARRLSELALALPLGGVGDVEGHLERASKGGVLEPLALRECAALARAAARTRGLLEARASETPRLWALAEPLSPSAALADRIERAIEPSGAISDRASAELAQARERSRGLHRALKAQVETLLADADMQRHLRDTYFTIRNERYVLPVLASARRAVPGIVHNASQSGQTLFVEPDSMVELGNELSIANAVAAEEEQRILRELTGALMADSGALARDLGILAALDVLEGSALLASDLDAHAPEVLSPFDGLRVGGAGAGFELLSLRHPLLVLQGKKVVPSHVRLDAPARALIVSGPNGGGKTVAITAVGLSALMLRAGLPVAAAEGSRLPFFLEVKAAVDERGDLAKDLSTFTAHLAAVKEMLAGAVPGSLILVDEIAADTDPREGAALAAAILESLVERGAAVLVTTHLDELKALALTDPRYANARVGFDAERLAPTYQLHLGSPGSSSAIEVAARVGLPAPLVERARAALTGHGGALGQALRALDDERARLAEERRAAESARDAARKAEERARAAEEVARRAQREAAARMGEALADELEAARAEVAELLAGLQARPTVKAATDAARQLDAWRATVAQAAKATQARADAGAEALPGGEVRPGVRVRIVSLGQEGEVVEVDGKDALVRAGPLKVRRPVADLVPLLGKAKDAAKLGRSRSEKLQAASEARPSAPPGLERRLDVRGLRVEELLREVERFLDRLYSDGEADCLILHGHGTGALKQALRDHLSASPYVGAFRAGDRHEGGDAVTVVSLRR",
    "output": "Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKEFIVLSEEVKAGQAKGLPIVALESTIISHGMPYPQNVQTAREVEQIIRDNGAVPATIALIDGKIKIGLSDEELEMFGNAQGVAKASRRDLGYLLATKKLGATTVAATMICAELAGIEIFVTGGIGGVHRGAETTMDVSADLEELAQTNVAVICAGAKSILDIGLTLEYLETKGVPVVGYGTDELPAFYTRQSGFDVNFQLDTPEEIAEMLSAKWQLGLKGGAVIANPIPEAEALEHGFITNIIEKALVEAEENGIQGKNVTPFLLGKVKELTEGKSLDANIALVKNNAVVGAKIAVAFNQLH",
    "output": "Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRSDKIKKGVEQAPARSLLHATGQIKSPGDMDKPFIAICNSYIDIVPGHVHLRELADVAKEAIREAGGIPFEFNTIGVDDGIAMGHIGMRYSLPSREVIADAAETVINAHWFDGVFYIPNCDKITPGMLLASVRTNVPAIFCSGGPMKAGLSAHGKALTLSSVFEAVGAFKDGSMSQEDFLDMEANACPTCGSCAGMFTANSMNCLMEILGMAVPGNGTTLAVSDARRDLIRESAFHLMDLVKKDIRPRDIITKDAIDDAFALDMAMGGSTNTVLHTLALANEAGIEDYDLERINDIAKRVPYLSKIAPSSSYSMHDVHEAGGVSAIVKELVDLGGAIHPDRITVTGKTIRENVADAKINNTDVIHPKENPYSPVGGLSMLFGNIAPKGAAIKVGGVDPSVQVFKGEAICFSSHDEAVEAIDNHTVREGHVVVIRYEGPKGGPGMPEMLAPTSSIVGRGLGKDVALITDGRFSGATRGIAVGHISPEAAAGGPIALVHDGDIITIDLPNRTLNVDVPDEVLEERRKELPKFKAKVKTGYLARYTALVTSAHTGGILQIPEDLID",
    "output": "Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNHIQEAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLQLNTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKSLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVFGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLIVNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET",
    "output": "Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQGNLEVLEGLARRLDISVPVDQLETEVQSRLKRLARSVKMHGFRPGKAPLSAVARQHGAGVRQEVLGETLKTRFGEAVQTHQLRIAGYPRFEPKADASAAAEMTFSASFEVYPEVKIDALDSATLNRPVVELGDADVAKTLEVLQKQRRTFATAARAAAEGDLVKFDYQGTVDGAPFEGGRGEDFAAVIGEGRLLKDFEQALVGLKAGDSKGFDLTFPAEYAARELADKTAHFEVQVKEVQAPVLPPVDAEFAEALGVEDGDVEKLKAEVKSNLEREVKRRVQAKLKEQAMELLLQKSTLDLPRSLVEMEMDRLRRMTEADMQSRGVQSMKLSADMFTGQAERRVRLGLILAEIVQANKLAAQPEQIRSLIQDQAQSYEEPDQVVQWYYQSPERMQEIESLALEENVVAWVADQATVVDVATSFDELMGRA",
    "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIANAQEILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQALQEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIFTELNIQCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVAANFFDQVEKEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMTLQANHELLTLTLPQGWLTQHPLGKEIIAQESQWQSYVHWPLEVH",
    "output": "Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTANDLKVGLFQDTSAF",
    "output": "Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKLIEYDETARRAMEAGVDKLAETVRVTLGPRGRHVVLAKSFGGPTVTNDGVTVARDIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLARALVKTGLRLVAAGINPIALGSGIGKAADAVSEALLASATPVSGKDAIAQVATVSSRDQLIGDLVGEAMSKVGHDGVVSVEESSTLGTELEFTEGVGFDKGYLSAYFVTDFDAQQAVLEDPLILLHQDKISSLPDLLPLLEKVAESGKPLMIIAEDIEGEALATLVVNSIRKTLKAIAVKSPYFGDRRKAFLQDLAAVTGAEVVNPDAGLVLREVGLEVMGSARRVVVSKDDTIIVDGGGAPEAVEARVNLLRSEIDRSDSEWDREKLGERLAKLAGGVAVIKVGAATETELKKRKESVEDAVAAAKAAVEEGIVAGGGSALIQARNALKDLRASLSGDEAVGVDVFSEALAAPLYWIATNAGLDGSVVVNKVSEVPAGHGLNAATLTYGDLAADGIVDPVKVTRSAVLNASSVARMVLTTETAIVDKPAEPEDDGHGHHGHAH",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALTAEEKQDIIAKYATHEGDTGSPEVQIALLTKRIADLTEHLKFHKHDHHSRRGLLLMVGDRRRLLDYLKKVDIERYRSLIERLGLRR",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKVSRHAKILEIINSKDIDTQEELAEELKKMGMNVTQATVSRDIKELKLIKVLGNTGKYKYATINHTESYMSDKLINIFAQTVINVENIDKLIIIKTISGSAPAAAEAIDTLGFDGVAGTIAGDNTIFVMARTNEKAQEITMKLKKIITA",
    "output": "Regulates arginine biosynthesis genes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKKFTCVQDIGDLKSALAESFEIKKDRFKYVELGRNKTLLMIFFNSSLRTRLSTQKAALNLGMNVIVLDINQGAWKLETERGVIMDGDKPEHLLEAIPVMGCYCDIIGVRSFARFENREYDYNEVIINQFIQHSGRPVFSMEAATRHPLQSFADLITIEEYKKTARPKVVMTWAPHPRPLPQAVPNSFAEWMNATDYEFVITHPEGYELDPKFVGNARVEYDQMKAFEGADFIYAKNWAAYTGDNYGQILSTDRNWTVGDRQMAVTNNAYFMHCLPVRRNMIVTDDVIESPQSIVIPEAANREISATVVLKRLLENLP",
    "output": "Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline . Is essential for arginine biosynthesis . Has no activity with either L-ornithine or L-aspartate as substrate . Has also no detectable AOTCase activity, being unable to convert N(2)-acetyl-L-ornithine to N(2)-acetyl-L-citrulline ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH",
    "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMQSFENVTVVKKANRYFDDKVTSRTVIFPDGSKKTLGIMLPGSYEFGTDKAEIMEILEGELEVFLPQESKWRTLRGGESFDVPAHSRFSLKVNETVDYCCSYVG",
    "output": "Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMEEISLQEKIEKLPLGVACIDGLTNGGLEAGIITEIFGEGGSGKSNVCMLAACSALRLGKKVVFIDSEGFSSERFLSICKADNSKLKVIRVFSLDDQEVAITKFSKIIEKDASYGLFILDSFSEFFRLERTGDNQSRVIDFQRQLSLLSSIAAKRKIPVLITNQIYQDIANGDILPFGGYVVDHIMKAIYRLERLPDGRRKMTVMKHRSVKEGNSVEFRIVQDGISCEVKNGN",
    "output": "Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSRAKKQ",
    "output": "This protein specifically catalyzes the removal of signal peptides from prolipoproteins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGSRTVGWWLLAAAVVLAAAAADSGEAERAAEQHSERISGSAGDVLEDNPVGRLKVFIYDLPRKYNKKMVNKDPRCLNHMFAAEIFMHRFLLSSAVRTLNPKEADWFYTPVYTTCDLTPAGLPLPFKSPRVMRSAIQYISHKWPFWNRTDGADHFFVVPHDFGACFHYQEEKAIERGILPLLQRATLVQTFGQENHVCLKEGSITIPPYAPPQKMQAHLIPPDTPRSIFVYFRGLFYDTGNDPEGGYYARGARASLWENFKNNPLFDISTDHPPTYYEDMQRAVFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVEEKDVPKLDTILTSMPIDDILRKQRLLANPSMKQAMLFPQPAQPRDAFHQILNGLARKLPHPEGVYLQPSDKRLNWTAGPVGDLKAW",
    "output": "Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDADELELKGHLKKLKKEELLRRKQLKESNLQKRELEYNNASKNTSIYISGLPTDKTTKEGLTEQFCKYGMIRTNRDGEPLCKLYVNDKGAFKGDALITYSKEESVTLAIEMMNESIFLGKQIRVERAQFQNKEGDNMHGKENDLKEFNGPEPPIKRLKKAKSEGEGEVIDYNDDESLAKADRTVIFANVFNIYKSYTNDDINDIQEDLLEGCEEIGQVDSISVSPNKGEATVVFKNNKVALQCCKIMTGRYFDGQKLLAFISGDENTSSTSDKNEDSEVEDDLI",
    "output": "U2 snRNP protein which helps to refold U2 into a structure favorable for its binding to SF3b and SF3a prior to spliceosome assembly. Mediates functional interactions between U2 RNA and PRP5. Enforces ATP dependence during formation of the prespliceosome by brokering an interaction between PRP5 and the U2 snRNP that depends on correct U2 RNA structure."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDGRFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKFFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADLEAKILEAKQKGYVPLYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGIPDSPERREKLHRVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL",
    "output": "Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTTAVLPRVGIGVDVHPFAAGRPCWVACLEWPGETGLAGHSDGDVAAHATCDALLTASCLGDLGKVFGTDRPEYAGASGAVLLAETARLLAVGGWVIGNVSVQVIGNRPRMAARREQAQAAMSAALGASVSLSATTTDGLGLTGRGEGLAAIATALVVRA",
    "output": "Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "METLYRVPFLVLECPNLKLKKPPWVHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPGYLMG",
    "output": "Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTICDTVDQYTIMSGDRLKIKDLLCNRLTECGWRNEVRLLCRNILLEKSANNSVSVDQLISEVTPKARTLVPDAVKKELLMKIRTILAETDEDN",
    "output": "Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in transcription elongation by recruiting the THO complex onto nascent mRNA. The AMEX complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). AMEX participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLKVAINGFGRIGRNVLRAVYESGKHQQIKVVAVNELAQPEAMAHLLQYDTSHGRFGKKISHDQEHLYVHHDSSEYDPIRILHLAEIELLPWRDLEVDIVLDCTGVFGSQADGQAHIEAGAQKVLFSHPGASDLDNTIIYGVNHETLKDEHRVVSNGSCTTNCIVPIIKVLDEAFGIESGTITTIHSSMNDQQVIDAYHNDLRRTRAASQSIIPVDTKLHKGIERIFPKFSNKFEAISVRVPTVNVTAMDLSVTISTNVKVNDVNQTIVNASQCTLRDIVDYTESPLVSIDFNHDPHSAIVDGTQTRVSNGQLVKMLVWCDNEWGFANRMLDTALAMQASSQVEQ",
    "output": "Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEIISLKRFILLMLATSSLLTSNIFCTDESRMPNLYSKKNYDKYSEPRGDLGWEKERSLTFEEVKDWAPKIKMNKPVVNKMPPSAANLPLRFGRNMEEERSTRAMAHLPLRLGKNREDSLSRWVPNLPQRFGRTTTAKSITKTLSNLLQQSMHSPSTNGLLYSMACQPQEIQNPGQKNLRRRGFQKIDDAELKQEK",
    "output": "Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptide NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide NPVF blocks morphine-induced analgesia (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALDKSVILLPLLVLVLLVLGCLGRESRAKKFQRQHMDSGSSPSSNSTYCNQMMKRRSMTHGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQTNCFKSKSSMHITDCRLTNGSRYPNCAYRTSPKERRIIVACEGSPYVPVHFDASVEDST",
    "output": "Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKSPAPSRPQKMALIPACIFLCFAALSVQAEETPVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFAMMVELLAQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYLWNDQQGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPTVKSATTQPSTKEAQPTP",
    "output": "Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDILTLGWVSVLVLFTWSISMVVWGRNGF",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRITVLSGSDSPEREVSLVSGRAVQAALETLGHEVTMVDPGPDLPVRLLENPPDFVWIALHGDKGENGKLQGLLDWLGLPYNGSGVTASAIAMDKVVSKRLFVAEGIPTPAYRVAEAVPQVSECQAWLAALGSPVVVKPADGGSTVGVTIAREAGHLPEAVRLALQYSPQVLIEQYIPGQEITVALLDGLVLPAIEIVPQGRDFYDYEAKYAPGGSRHLIPPNLAADVLKASVDAAYRACRAVGSTGLVRADVRVDPEGRPWVLEVNTLPGMTATSLAPEAAQAAGIDFEQLIQRIIDRSLD",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVTKEQRRQKIKARVRGKISGTQERPRLTVFRSNKQIYAQLIDDIAGRTLASASSLKLEMTGSKKEIAAKVGDEIAKAATEAGISTVVFDRNGYLFHGRIKELADAARKGGLKF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIFKDYDFLQNYDLKNFGEKVKIYKELLSKFNRIHNLTHLKNIDENIFDSIKILDFYDFSKAKNIADIGSGAGFPAVFLAFLLQSNFHLFEPNPKKTAFLRTLKIECELSNLHIYKEKVQEYKNTFKADIITSRALMDIKPLLEICTNLKDENTVFILWKGSEIYQELENIKDYEIFENNLRKYCIVK",
    "output": "Specifically methylates the N7 position of guanine in position 527 of 16S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLSLDQINTLVTLPGVGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYLPELKALAQQLMQERG",
    "output": "Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMSLAVINGNNKQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGDVDGKPAAGGMLLQIMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEEGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADPQVH",
    "output": "Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTLLNVCGLSHHYAHGGFSGKHQHQAVLNNVSLTLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNISWHGESLAKLNRAQRKAFRRDIQMVFQDSISAVNPRKTVREILREPMRHLLSLKKSEQLARASEMLKAVDLDDSVLDKRPPQLSGGQLQLVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIAETQAVGDKLTFSSDAGRVLQNAVLPAFPVRRRTSEKV",
    "output": "Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MHTTDTETFEEQFAIEQRLVDSVVASFDSTTDPRLKELMQSLTRHLHAFIREVRLSEDEWSNAIAFLTAVGNITDDRRQEFILLSDVLGVSMQTIAVSNPAYEDATESTVFGPFFVEDAPEVTLGGDIAGGATGQPCWIEGTVTDTAGNPVPEARIEVWQNDEDGFYDVQYSDGRVSGRAHLFSDAHGRYRFWGMTPVPYPIPSDGPVGKMLAATNRSPMRVAHLHFMVTADGLRTLVTHIFVAGDPQLERGDSVFGVKDSLIKDFVEQPPGTPTPDGRHIGDRNWARCEFDIVLAPEQI",
    "output": "Involved in the degradation of para-nitrophenol (4-NP). Catalyzes the conversion of hydroxyquinol to malelylacetate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLTLKIAVYIVVAFFVAIFVFGFLSNDPARNPGRRDLE",
    "output": "One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGKNIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD",
    "output": "Plays an important role in the elongation step of protein synthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVKLSKEAKQRLQQLFKGGQFAIRWGFIPLVIYLGFKRGADPGMPEPTVLSLLWG",
    "output": "Required for assembly and stability of the TOM complex (By similarity). Positive regulator of PRKN translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE",
    "output": "Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis, programmed cell death, biofilm formation and cell wall metabolism. Participates also in sensing and responding to host defense cationic antimicrobial peptides (HDPs). Functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to the conserved aspartic acid residue in the regulatory domain of LytR. In turn, LytR binds to the upstream promoter regions of target genes including lrgA and lrgB, to positively regulate their expression. Possesses also a phosphatase activity that dephosphorylates and thus inactivates LytR."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MASLLCCGPKLAACGIVLSAWGVIMLIMLGIFFNVHSAVLIEDVPFTEKDFENGPQNIYNLYEQVSYNCFIAAGLYLLLGGFSFCQVRLNKRKEYMVR",
    "output": "Endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds. Hydrolyzes UpU bonds at a lower rate (By similarity). Regulates the activity of vacuolar (H+)-ATPase (V-ATPase) which is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity). Required at an early stage of receptor-mediated endocytosis (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATDDELMLIHKYDYVEAIKHASHGIISEDEAKKYGLNDEENSQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLAKEYNQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFKLTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIMFGGGGYNIWRVVPRAWSHVFLSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTRQ",
    "output": "Role in growth on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "NLVQFELLIMKVAKRSGLLSYSA",
    "output": "Snake venom phospholipase A2 (PLA2) that significantly inhibits ADP-induced platelet aggregation in platelet-rich plasma of human, rabbit and guinea pig. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKELQATLDKAEKTLVKVMQEDGTESDFE",
    "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSGSSMGRLFTVTSFGESHGPGIGCVVDGCPPGLALSEADIQLELDRRKPGTSRHVTQRREPDTVEILSGVYEGKTTGTPIALLIRNTDQRSKDYGNIADTFRPGHADYCYWHKYGTRDPRGGGRSSARETAVRVAAGAIAKKWLNEKYGIVIRGHMTQIGEVAIPFKSWEHVGGNPFFSADPDIVPRLEEYMDSIRKSLDSIGARLRVVADNVPVGWGEPVFDRLDADIAYAMMSINAVKGVEIGAGFGCVTQKGSEHGDELTPRGFASNHAGGVLGGISTGQQIDVSIAIKPTSSIAQPRRSINKQGEAVTMETHGRHDPCVGIRATPIAEAMLALVLIDHALRHRAQCGDVRVETPRIAGHIG",
    "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGEKATQDFKSVKSTLRALEEIESGNVVIHPDPSAKRASVRARIEAERLAKEEEERKIKEQIAKEKEDGEKI",
    "output": "Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIQQAIAKVLEGEDLTRAEAASVMTEIADGGATPAQSGAFLAALRMKGETVDEIAGAADVMRQRADRVRVDRDVFIDTCGTGGDGRHTFNISTTAAFVAAGAGVCVAKHGNRAVSSRSGSADVLAALGVNVDADKETVERCIEEVGIGFLFAVRLHPAFKAIAGVRRELGVRTIFNLLGPLANPAGARHQVLGVYEARWVPVLGGVLAALGAAHAFVVHGEGLDEIAVTGMTHVCEVRDGQVERYTIRPEDLGLPRRDAAELVGGDAAANARIVTDVLEGQAGGPRDAVLANAAAALVCAGAAKDLRDGVARAARSIDSGAAREKLRQLVAATTVPA",
    "output": "Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQVELYTCCFLCLLPFSLSATRKYYLGAVELSWDYMQSDLLSALHADTSFSSRVPGSLPLTTSVTYRKTVFVEFTDDLFNIAKPRPPWMGLLGPTIQAEVYDTVVIVLKNMASHPVSLHAVGVSYWKASEGAEYEDQTSQKEKEDDNVIPGESHTYVWQVLKENGPMASDPPCLTYSYFSHVDLVKDLNSGLIGALLVCKEGSLAKERTQTLQEFVLLFAVFDEGKSWHSETNASLTQAEAQHELHTINGYVNRSLPGLTVCHKRSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTAQTFLMDLGQFLLFCHIPSHQHDGMEAYVKVDSCPEEPQLRMKNNEDKDYDDGLYDSDMDVVSFDDDSSSPFIQIRSVAKKHPKTWVHYIAAEEEDWDYAPSGPTPNDRSHKNLYLNNGPQRIGKKYKKVRFVAYTDETFKTREAIQYESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGINYVTPLHTGRLPKGVKHLKDMPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFINLERDLASGLIGPLLICYKESVDQRGNQMMSDKRNVILFSVFDENRSWYLTENMQRFLPNADVVQPHDPEFQLSNIMHSINGYVFDNLQLSVCLHEVAYWYILSVGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWVLGCHNSDFRNRGMTALLKVSSCNRNIDDYYEDTYEDIPTPLLNENNVIKPRSFSQNSRHPSTKEKQLKATTTPENDIEKIDLQSGERTQLIKAQSVSSSDLLMLLGQNPTPRGLFLSDLREATDRADDHSRGAIERNKGPPEVASLRPELRHSEDREFTPEPELQLRLNENLGTNTTVELKKLDLKISSSSDSLMTSPTIPSDKLAAATEKTGSLGPPNMSVHFNSHLGTIVFGNNSSHLIQSGVPLELSEEDNDSKLLEAPLMNIQESSLRENVLSMESNRLFKEERIRGPASLIKDNALFKVNISSVKTNRAPVNLTTNRKTRVAIPTLLIENSTSVWQDIMLERNTEFKEVTSLIHNETFMDRNTTALGLNHVSNKTTLSKNVEMAHQKKEDPVPLRAENPDLSSSKIPFLPDWIKTHGKNSLSSEQRPSPKQLTSLGSEKSVKDQNFLSEEKVVVGEDEFTKDTELQEIFPNNKSIFFANLANVQENDTYNQEKKSPEEIERKEKLTQENVALPQAHTMIGTKNFLKNLFLLSTKQNVAGLEEQPYTPILQDTRSLNDSPHSEGIHMANFSKIREEANLEGLGNQTNQMVERFPSTTRMSSNASQHVITQRGKRSLKQPRLSQGEIKFERKVIANDTSTQWSKNMNYLAQGTLTQIEYNEKEKRAITQSPLSDCSMRNHVTIQMNDSALPVAKESASPSVRHTDLTKIPSQHNSSHLPASACNYTFRERTSGVQEGSHFLQEAKRNNLSLAFVTLGITEGQGKFSSLGKSATNQPMYKKLENTVLLQPGLSETSDKVELLSQVHVDQEDSFPTKTSNDSPGHLDLMGKIFLQKTQGPVKMNKTNSPGKVPFLKWATESSEKIPSKLLGVLAWDNHYDTQIPSEEWKSQKKSQTNTAFKRKDTILPLGPCENNDSTAAINEGQDKPQREAMWAKQGEPGRLCSQNPPVSKHHQREITVTTLQPEEDKFEYDDTFSIEMKREDFDIYGDYENQGLRSFQKKTRHYFIAAVERLWDYGMSRSPHILRNRAQSGDVQQFKKVVFQEFTDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIVVTFKNQASRPYSFYSSLISYDEDEGQGAEPRRKFVNPNETKIYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLIGPLLICRSNTLNPAHGRQVTVQEFALVFTIFDETKSWYFTENLERNCRAPCNVQKEDPTLKENFRFHAINGYVKDTLPGLVMAQDQKVRWYLLSMGSNENIHSIHFSGHVFTVRKKEEYKMAVYNLYPGVFETVEMLPSQVGIWRIECLIGEHLQAGMSTLFLVYSKKCQTPLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKDPFSWIKVDLLAPMIIHGIMTQGARQKFSSLYVSQFIIMYSLDGNKWHSYRGNSTGTLMVFFGNVDSSGIKHNIFNPPIIAQYIRLHPTHYSIRSTLRMELLGCDFNSCSMPLGMESKAISDAQITASSYLSSMLATWSPSQARLHLQGRTNAWRPQANNPKEWLQVDFRKTMKVTGITTQGVKSLLISMYVKEFLISSSQDGHNWTLFLQNGKVKVFQGNRDSSTPVRNRLEPPLVARYVRLHPQSWAHHIALRLEVLGCDTQQPA",
    "output": "Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKTLLLTLVVVTIVCLDLGDSLRCYMGPKTPRTCPPGENLCFTKTWCDPRCSLLGKLVKLGCAATCPIPKSYEDVTCCSTDNCNRFPKWERSRPRPRGLLSSIMDHP",
    "output": "Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRVKIVSKPTSQLNNIIEKIKNISTKLGFEVVDKDFDYVIAVGGDGTLLRAVKQNKPVIAVKAGRRGLLMDVPVDKFEEALLRLKKGDYEEEEYMLLEMIYNDKVELGFNEVGILYDRPEAIKVGISFDTERVSVEGDGVLVSTPQGSSGWGMSATNSLLYKDLSAIEIIFVNPIFYYLRSVVIPPKPLTLRLEDKGYPQTARAVVDGEVVTLIKTNQEITVRVSQRKAKILRFFKLDLIGEVLHAYHI",
    "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAGSKSPKGEFAGRKLLLKRKASRWHHYKYVNKALSLKLKADPLEGAPMGRGIVVEKVGLEAKQPNSAIRKCVRVQLIKNGRQVTAFAPGNHAINFIDEHDEVVIEGIGGPSGQAKGDIPGVRYKVVMVGKNSIRELVRGRQEKVKR",
    "output": "With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDSEDDPLLQDVWLEEEQPEDEACRGIPGPGLQSGAQGCWRRWTLPSRPPTLGFWSTLGWAFTNPCCAGLVLFLGCSIPMVLSAFMFLYYPPLDIDISYNAFEIRNHEASQRFDALALALKSQFGSWGRNRRDLADFTSETLQRLISEQLQQLHLGNHSRPASRAPRSAPRDTVATQTSAANSSERRRREAPSPEGQVTNQSRARRGASRWDYSRTYVSANTQTHAHWRIELIFLARGDAERNIFTSERLVTIHEIERKIMDHPGFREFCWKPHEVLKDLPLGSYSYCSPPSSLMTYFFPTERGGKIYYDGMGQDLADIRGSLELAMTHPEFYWYVDEGLSVDNLKSSLLRSEILFGAPLPNYYSVDDRWEEQRAKFQSFVVTYVAMLAKQSTSKVQVLYGGTDLFDYEVRRTFNNDMLLAFISSSCIAALVYILTSCSVFLSFFGIASIGLSCLVALFLYHVVFGIQYLGILNGVAAFVIVGIGVDDVFVFINTYRQATHLEDPQLRMIHTIQTAGKATFFTSLTTAAAYAANVFSQIPAVHDFGLFMSLIVTCCWLAVLFTMPAALGLWSLYMAPLESSCQNSCHQKCGRKSSLHFPGDLFTAPERAGGGPAQGPLPYLDDDIPLLNVEDEPASLELGDVSLVSVHCEGLQPTPDANSRGQLLAQLQELLHHWVLWAAVKSRWVIVGLFASILILSLVFASRLRPASRAPLLFRPDTNIQVLLDLKYNLSAEGISCITCSGLFQEKPHSLQNNVRTSLEKKKRGSGVSWASRTETTAQESMSTVYISKVKSKGHPAVYRLSLNASLPAPWQAVSPGDGEVPSFQVYRAPFGDFTKKLTACMSTVGLLQAASPSRKWMVTALACDARRGWKFDFSFYVATKEQQHTRKLYFAQSHKPPFHGRLCVAPPGCLLSSSPDGPTKGFFYVPSDKVPKARISATFGFNPCVNTGCGKPAVRPLVDTGAMVFVVFGIIGLNRTQQMDNHVIGDPGSVIYDSSFDLFKEIGHLCRLCKAIAGNSELVKPGGAQCLPSGYSISSFLQMLHPECKELPEPNLLPGQLSHGAVGVKEGRVQWISMAFESTTYKGKSSFQTYSDYLRWESFLRQQLQTFPEGSALHRGFQTCEHWKQIFMEIIGVQSALYGLVLSLLICVAAVAVFTTHVLLLLPVLLSILGIVCLVVTIMYWSGWEMGAVEAISLSILVGSSVDYCVHLVEGYLLAGENLPPQLSQDPSSQRQWRTLEAVRHVGVAIVSSALTTVIATVPLFFCIIAPFAKFGKIVALNTGVSILYTLTVSTALLGIMAPGSFTRTRTSFLKALGAVLLAGALGLGACLVLLRSGYKIPLPSGATL",
    "output": "Plays a role in neuronal proliferation and differentiation. Plays a role in the accumulation of cellular cholesterol. Involved in intracellular lipid droplet formation. May contribute to cholesterol homeostasis in neuronal cells."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSFNTFGHLFRVTTFGESHGVAIGCVVDGCPPLIPLTEADIQGDLDRRRPGQSRFTTQRQEADQVKILSGVMVHPETGVQVTTGTPIALLIENTDQRSKDYSDIQNKYRPGHADFTYEAKYGIRDYRGGGRSSARETATRVAAGAIARKVIAGMTVRGALVQIGPHKIDRDKWDWDEIGNNPFFCPDKDKAAFYADYLDGIRKSGSSIGAVVEIVAEGVPAGLGAPIYAKLDGDLAAALMSINAVKGVEIGDGFASAELTGEQNADEMRTGNHGPAFLSNHAGGILGGISTGQPVVARFAVKPTSSILTPRKTVDRTGHDTEILTKGRHDPCVGIRAVPVGEAMVACVLADHLLRHRGQVGG",
    "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTRPLEQAVAAIVCTFQEYAGRCGDKYKICQSELKELLQKELPTWTPSEFRECDYNKFMSVLDTNKDCEVDFGEYVRSLASLCLYCHEYFKECPPEPPCPQ",
    "output": "Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MADLDDIKDGKDFHTDKPQTNTLFSLKGCGALDWGMQSRLARIFNPRTRKTVMLAFDHGYFQGPTTGLERIDINIAPLFEYADVLMCTRGILRSVVPPAINKPVVLRASGANSILTELSNEAVAVAMDDAVRLNSCAAAAQVYIGSEHEHQSIKNIIQLIDAGLRVGMPIMAVTGVGKDMARDQRYFSLATRIAAEMGAQIIKTYYVDKGFERIAAGCPVPIVIAGGKKLPEREALEMCYQAIDQGASGVDMGRNIFQSEDPVAMIKAVHAVVHHNETAERAYELFLSEKG",
    "output": "Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEVMNLIEQPIKVTEWQQTYTYDSGIHSGVNTCVPSVSSKGIMDEDDACGRQYTLKKTTTYTQGVPQNQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQTTNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQGLVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIPINEPYADDMDATYRPMYSSDVPLDPLDMHMDLDGDYPMDTYSDGLRPPYPTADHMLA",
    "output": "Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQAYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLVIKKLLQVSAEVCRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISNKEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTVYIEPRALVSLNEELTQLQADERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRAKYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGKTIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHIVEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYGIETAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATDHDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAALEAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKQAKKWRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQPKKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGTGVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG",
    "output": "Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIVGIGSDLCDIRRIERSLERFGERFTQRVFTPGERARSDRRAARAPSYARRFAAKEACAKALGTGLSQGVFWRDMEVVNLPSGAPTLRLTGGAAARLAALVPPGHRARLHVSLTDDPPLAQAFVVIEALRDESC",
    "output": "Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNISSFSDNLTKILGKYEDLSEKLSSGIGGEEFVKASKEYADLEDIVQKIKEYNKAKAELEEANNFKQEPSLDKATLEMIEEEIRNLEDSLPTLERSVKIALLPKDEADSKSAIIEIRAGTGGEEAALFAAKLFNMYQRYAELKGWRFEILSIDETGIGGYKEVSASIKGKDVFSKLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEVEDVDIKLEEKDLRIDTYRASGAGGQHVNTTDSAVRITHIPTGITVALQDEKSQHKNKAKALKILRARIYEEERRKKDQERANNRRKQIGSGDRSERIRTYNFPQGRVSDHRINLTLYKIDEVINGQLDEFIEALIANDEAKKLSDI",
    "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKRDKRLEIIKEIVTNNKISTQEELQSLLLERGVEVTQATLSRDIRKLNIIKKRDKGESFYSFLTSGNSKINSDLQLYFYNFVISAKSVGALVVIRTKLGEADVLANALDDERDSRTDILGTIAGADTLLVICASEKAANILTAEIKYILLG",
    "output": "Regulates arginine biosynthesis genes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNKTTRVMPAHKHIALVAHDNYKPELLRWVKENKDALQGHFLYATGTTGRILSKETGLAIKSLLSGPMGGDQQLGALISEGKIDMMIFFWDPLNAVPHDPDVKALLRIATVWNVPVAMNRASAKFMISAPQMEEEVSIEIPDYDAYLAERV",
    "output": "Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MYIQSLALTSYRNYEHTELQFDNKVNVMIGENAQGKTNLMEAIYVLSMAKSHRTSNDKELIRWDQDYAKIEGRVIKKNGPLPMQLVISKKGKKGKVNHIEQQKLSHYVGALNTIMFAPEDLSLVKGSPQIRRRFLDMEIGQVSAVYLHDLSLYQKILSQRNHYLKQLQTRKQTDQAMLEVLTEQLIDAAAKVVKRRLTFTKQLEKWAQPLHFGISRELETLTLQYHTAIEVSEASDLSKIKNSYEESFQKLRDREIDRGVTLWGPHRDDLLFFVNGRDVQTYGSQGQQRTTALSLKLAEIDLIHEEIGEYPILLLDDVLSELDDYRQSHLLHTIQGRVQTFVTTTSVEGIDHATLKEAEIFRVASGKVID",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIIHPKVRGFICTTTHPLGCERNVLEQIAATRARGVRNDGPKKVLVIGASSGYGLASRITAAFGFGADTLGVFFEKPGTASKAGTAGWYNSAAFDKHAKAAGLYSKSINGDAFSDAARAQVIELIKTEMGGQVDLVVYSLASPVRKLPGSGEVKRSALKPIGQTYTATAIDTNKDTIIQASIEPASAQEIEETITVMGGQDWELWIDALEGAGVLADGARSVAFSYIGTEITWPIYWHGALGKAKVDLDRTAQRLNARLAKHGGGANVAVLKSVVTQASAAIPVMPLYISMVYKIMKEKGLHEGTIEQLDRLFRERLYRQDGQPAEVDEQNRLRLDDWELRDDVQDACKALWPQVTTENLFELTDYAGYKHEFLKLFGFGRTDVDYDADVATDVAFDCIELA",
    "output": "Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It can also use crotonyl-CoA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPNAIVAAEQYREIFLNQHPIMDVRAPIEFTRGAFPNSTNLPLMLDSEREKVGTCYKQSGQQAAIALGHSLVNGPIKQQRIEAWASYVKANPKAYLYCFRGGLRSQLTQQWLKEAGVEVPYIQGGYKAMRQYLIGVIEAAPAQQPLLSLSGMTGCGKTDFLLLRKEAVDLEGIANHRGSSFGKNIDPQPTQINFENQLAIALLQHQTSGVACLLLEDESFLIGRSALPQTFYNAMQAANVLVLEESDDVRLERLRDEYVHKMYSGFCERLGAEAGFAAFSDYLLQSLVSIRKRLGGKQHQELQDLMQQALDQQINQNDTSLHLVWINLLLHKYYDPMYLYQLQNKSERVLFKGSHQAMHEWLDSYQTR",
    "output": "Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MELNAKPRKSQEKLAEGLIPAVAYNKDNNISFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKTVQMDKRRRTPIHVDFYMVTYGEPIEVSVPVHTTGKSQGEIMGGLVDIVLHNLSIVAPGPRRIPQELTVDVSRLNIGDHITAGDVKLPEGCTLAVAADSVVISVLPPRMTADEAAAETQAAQVAGLVAAGELSEEAAAAVLEGDASIEEIKAEAHAAEGTQAEGSTEEGQQQ",
    "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH",
    "output": "May regulate the activity of kinases."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGEGDGDLK",
    "output": "Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLSLKLPRLFSIDQIPQVFHEQGILFGYRHPQSSATACILSLFQMTNETLNIWTHLLPFWFFAWRFVTALYMTDIKNDSYSWPMLVYMCTSCVYPLVSSCAHTFSSMSKNARHICYFLDYGAVNLFSLGSAIAYSAYTFPDALMCTTFHDYYVALAVLNTILSTGLSCYSRFLEIQKPRLCKVIRVLAFAYPYTWDSLPIFYRLFLFPGESAQNEATSYHQKHMIMTLLASFLYSAHLPERLAPGRFDYIGHSHQLFHVCVILATHMQMEAILLDKTLRKEWLLATSKPFSFSQIAGAILLCIIFSLSNIIYFSAALYRIPKPELHKKET",
    "output": "Plasma membrane progesterone (P4) receptor coupled to G proteins . Seems to act through a G(i) mediated pathway . May be involved in oocyte maturation ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSNLKGALQPFTPLLLRYSGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLNCIQALAGTTGSPEPALRRFELALLGHLGYGVNFTHCAGSGERVDDTMTYRYREEKGFFASVVIDNNTFTGRHLKALEAREFPDVDTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTKKD",
    "output": "Involved in DNA repair and RecF pathway recombination."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSNLRTLVFFATPPHDCSYLPDREATTMFVDPRAHIDKKLYSQLTALGFRRSGSHYYRPHCESCNACVPVRLQVGQFEPDRNQRRVLRKNADLDCKLVPAAFSERYYRLYAHYIEERHRDGDMYPPSREQFTSFLVEGATDSWFLEMSLDGELVGLAAVDLLDDGLSAIYTVFAPELEHRSLGTFAVLWQIEEAKRRELPHLYLGYWIKECRKMNYKTRFQPIEALRDGHWREMSTD",
    "output": "Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIDKSVFIHPTAIVEDGAVIGANAHIGPFCIVGPQVEIGEGTVLKSHVVVNGQTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHVAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREGLVAIRNAYKLLYRSGKTLDEAKLEIAELAEKHPEVKAFTEFFERSTRGPIR",
    "output": "Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNIELALTLVSLVLVVSAGPLVVVLLSARGGNL",
    "output": "A core subunit of photosystem II (PSII)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDSVSVNQILYPEVHLDSPIVTNKLVSILEYARIRHNYQLLDTTLVRNIKERISEGFSNQMIINCIEIGSIINQTLLSYPKHNHVIYPNCNKLLFHAQDRVISLRLRNIFKRGNSIYSKITDGVKKCLNDINLNIGLGGALDKTIGTKIDEAGIIMQSSQWFEPFLLWFTIKTEMRSVIKSSTHNCRKRRQNPVFVKGESLNVLVSRDLVCIIDLTSHIVYYLTFEMVLMYCDVIEGRLMTDTAMAIDQRYSTLHVRIRYLWDLIDGFFPDLGNSTYQLVALLEPLSLAYLQLKDITFSLRGAFLSHCFAEIQEILQDNGFYTEETFQTLTQALDFVFITEDIHITGEIFSFFRSFGHPRLEAITAAENVRKHMNQPKVVSYETMMKGHAIFCGIIINGYRDRHGGTWPPMDLPVHASPIIRNAHASGEGITYSQCIENWKSFAGIRFKCFMPLSLDSDLTMYLKDKALAALRKEWDSVYPKEFLRYNPPRSTESRRLVNVFLEDSQFDPYNMIMYVISGQYLEDPDFNLSYSLKEKEIKEVGRLFAKMTYKMRACQVIAENLISNGIGKYFKDNGMAKDEHDLTKSLHTLAVSGVPKDKKDSHRGLTNQRKSLKPAPYRGTRHSVSSPSSRYIDPNPNFCTSRREDNDIEIYETVSAFITTDLKKYCLNWRYETISIFAQRLNEIYGLPSFFQWLHRRLEQSILYVSDPHCPPDLDRHVDLNTAPNSQIFIKYPMGGVEGYCQKLWTISTIPYLYLAAHESGVRIASLVQGDNQTIAVTKRVPSTWSYALKKSEASRVTTEYFIALRQRLHDVGHHLKANETIISSHFFVYSKGIYYDGMLISQSLKSIARCVFWSETIVDETRAACSNISTTLAKAIEKGFDRYLAYTLNILKIIQQVLISLGFTINSAMTRDVIEPLLQDHCLLTKMAILPAPIGGFNYLNMSRLFVRNIGDPVTSSIADLKRMIRSGLLGVEILHQVMTQYPGDSSYLDWASDPYSANLPCVQSITRLLKNITARHVLINSPNPMLRGLFHDESQDEDEALAAFLMDRKIIIPRAAHEILDNTITGAREAIAGMLDTTKGLIRASMKRGGLTPRIITRLSTYDYEQFRAGIRLFSGKGHDQLIDQDSCSVQLARALRNHMWAKLAKGRPIYGLEVPDILESMKGYMIRRHESCLLCASGSHNYGWFFIPANCQLDSITEGTSALRVPYIGSTTEERTDMKLAFVKSPSRSLKSAVRIATVYSWAYGDDDESWQEAWTLAKQRADISLEELRMITPISTSTNLAHRLRDKSTQVKYSGTSLIRVARYATISNDNLSFIIDDKKVDTNFIYQQGMLLGLGILEHLFRLSSTTGDSNTVLHLHVETDCCVIPMSDHPRVPGLRKVVIPRNICTNPLIYDSNPIIEKDAVRLYNQSHRKHIVEFVTWTTGQLYHVLAKSTAMSMVEMITKFEKDHLNEVTALIGDDDINSFITEFLLVEPRLFTVYLGQCAAINWGFEIHYHRPSGKYQMGELLFSFLSRMSKGVFKILANALSHPKVYRRFWDSGMIEPVHGPSLDSQNLHITVCNLIYNCYMIYLDLLLNDELDDFSFILCESDEDVIPERFDNIQARHLCILSDLYCNPRDCPQIRGLTPTQKCAVLSGYLKSKALESHVGLTWNDKPILIDQYSCSLTYLRRGSIKQIRLRVDPGFITDAVGCLERRPLRNNSTSKASELTSGFDPPKDDLAKLLSQLSTRTHNLPITGLGVRNYEVHSFRRIGINSTACYKAVEIASVIKNEFTSEEHGLFLGEGSGAMLTVYKELLRLSRCYYNSGVSVESRTGQREISPYPSEVSLVEHQLGLDKLVTVLFNGRPEVTWVGSVDCYKYILSQISASSLGLIHSDIESLPDKDIIEKLEELSAILSMTLILGKVGSVLVIKIMPVSGDWVQGFILYALPHFLRSFIVYPRYSNFVSTEAYLVFTGLRAGRLINPEGIKQQILRVGIRTSPGLVGHILSSKQTACVQSLHGPPFHAKSFNPHLQGLTSIEKVLINCGLTINGLKVCKNLLHHDISSGEEGLKGSITILYRELARFKDNHQSSHGMFHAYPVLIASQERELVSIIAKKYCGYILLYSGDLYEITRIVRNLKANHIIFDLHRNLFMDNLSRSDRSLILTTIPKKNWLFQLETKEIKEWFKLLGYSALIRNH",
    "output": "RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymerase binds to the genomic RNA at the 3' leader promoter, and transcribes subsequently all viral mRNAs with a decreasing efficiency. The first gene is the most transcribed, and the last the least transcribed. The viral phosphoprotein acts as a processivity factor. Capping is concommitant with initiation of mRNA transcription. Indeed, a GDP polyribonucleotidyl transferase (PRNTase) adds the cap structure when the nascent RNA chain length has reached few nucleotides. Ribose 2'-O methylation of viral mRNA cap precedes and facilitates subsequent guanine-N-7 methylation, both activities being carried by the viral polymerase. Polyadenylation of mRNAs occur by a stuttering mechanism at a slipery stop site present at the end viral genes. After finishing transcription of a mRNA, the polymerase can resume transcription of the downstream gene.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGIKIYRPKTSSLRYKTTLSFDELSKGNDPLKSLTKGKVSRAGRDSSGRISVRRRGGGHKRRYREIDFARRDKFGIPARVAAIEYDPNRSPNIALLVYRDGDKRYIIAPKGVKVGDILESGPNAPIKIGNALPLENIPVGKMVHNIELNIGKGGQLVRGAGGYAMIIASDGDYVTVKLPSGEMRMIFKKCIATLGEVGNEDYMNVSIGKAGKSRWLGRRPKVRGVAMNPIDHPHGGGEGKTSGGRHPVSPWGQPAKGYKTRKKNKYSDKFIVKRRNN",
    "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKLLVLCVFAMMATLAVSRRYQFVQHQYIRKAFEVALKVEIIAGFDRTLVKWLRNHGRGLNENQRKVLYFVNRRYMQTHWQNYMLWIVKKTNALGRPPVVADYRALGAEIGRRIDMGYFYNFLKNRVMIPKYLPYMRRLNNMRPEDVPVANRNPGK",
    "output": "Creates a 3 um hole in the egg vitelline layer through which the sperm passes. Does not have enzyme activity. Species-specific interaction between the sperm protein lysin and the egg protein VERL exposes a basic surface on lysin that may dissociate the egg vitelline layer via electrostatic repulsion. Plays a role in ensuring species-specific fertilization."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNLNIETTTQDKFYEVKVGGELDVYTVPELEEVLTPMRQDGTRDIYVNLENVSYMDSTGLGLFVGTLKALNQNDKELYILGVSDRIGRLFEITGLKDLMHVNEGTEVE",
    "output": "Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTYNAGNYDVIVVGAGHAGVESAYAAARMGAKTLMLTLNLDMIAFMPCNPSIGGPAKGIVVREIDALGGIMGKVIDKSYIQMRMLNTGKGPAVQALRAQADKPIYMKEMKHLMENEENLTIRQGMVNELIVEDGICKGVITETHAAYYADSVIVTTGTFMRGKVLMGDLEYESGPNNQRVSIKLSEDLEKHGFEITRFKTGTPPRVNSHTIDYSKTEIQPGDDNPKSFSYETTEQITDQIPCWLTYTNEFTHQVINDNLELSSMYSGMKRGTGPRYCPSIEDKIVRFNDKPRHQIFLEPEGRDTEEVYVQGLSTSLPESIQHEMIKSVPGLEKAEIMRAGYAIEYDAVVPTQLWPTLETKRLPGLFTAGQINGTSGYEEAAGQGLMAGMNAAAKSLNKEPIILDRSQAYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDIGYDYGLITEERYQRFTEKKQQIEQEKKRLSKIIIKPTEDIQDIMEKAGASRLKEAIKAYDLMKRPELSYDIVDQMIESNLELSEEVKEQVAIQIKYEGYIKKAKEQVDRMLKMEDKKIPEDIDYDAINGIATEAVEKLKKVRPLSVGQASRISGVNPADVSILLVYIEQGSIAKVAND",
    "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSQKIQQHQFPDFYCCYLLQSINKRQSFYVGSTPNPVRRLRQHNGKLAVGGAYRTKRDGSRPWEMIMIVRGFPSKIAALQFEHAWQHGYQTHYIAEKDRVVKHKAGGRTLHHKVALMKLLLKHEFFQRMNLIVDVFNIKAWEVWKQDKFFIERDRFPINIQINENALEEPKEKTVDVLMDHSDENLKVVEAVYTKVIENERNIFETFEKKLTTGVVRCEICEKEIDYTSEEQNLKPFVALCNNKDCGSVNHLKCLHRYFLDDEQLIVGRRNLIPRGGKCPKCDTFCDWTTLVKFSTRMKLAHGK",
    "output": "Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for simple Y, 5'-flap and replication fork-like structures. It cleaves the strand bearing the 5'-non-homologous arm at the branch site junction and generates ligatable, nicked products from the 5'-flap or replication fork substrates. Plays a critical role in maintaining the integrity of the ribosomal DNA (rDNA) loci, where it has a role in re-starting stalled replication forks. Has Holliday junction resolvase activity in vitro."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNATIFAFLLLLNLAMHNATEQSSETDMDDTLLIPEINRGRCIEEGKWCPKKAPCCGRLECKGPSPKQKKCTRP",
    "output": "Probable ion channel inhibitor."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "LCNERPSQTWSGNCGNTAHCDKQCQDWEKASHGACHKRENHWKCFCYFNC",
    "output": "Possesses antimicrobial activity sensitive to inorganic cations. Binds specifically to the fungal plasma membrane. Has no inhibitory effect on insect gut alpha-amylase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKSLSFSFLVTLFLYLTLSSARTLGKDVNKRVTAGSLQQVTGFGDNASGTLMYIYVPKNLATNPGIVVAIHYCTGTAQAYYTGSPYAQLAEQYGFIVIYPQSPYSGTCWDVSSQAALTHNGGGDSNSIANMVTWTISQYNANTAKVFVTGSSSGAMMTNVMAATYPELFAAATVYSGVGAGCFYSSSNQADAWNSSCATGSVISTPAVWGGIAKNMYSGYSGSRPRMQIYHGSADTTLYPQNYYETCKQWAGVFGYNYDSPQSTLANTPDANYQTTNWGPNLQGIYATGVGHTVPIHGAKDMEWFGFSGSGSSSTTTASATKTSTTSTTSTKTTSSTSSTTTSSTGVAAHWGQCGGSGWTGPTVCESGYTCTYSNAWYSQCL",
    "output": "Acetylxylan esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGKCSYRFISLQTLTPNSLLDHSPNPTIWAKPLQIGSLTLHSRVLQSPLSGVTDLVFRRLVRRYAPQAMLYTEMVSATEIHHLRTLPQVMEIDPRENPISIQLFDCRPDFMAEAAQKAVAQGAQSVDINMGCPVNKITKKGGGSSLLRQPAVAEAIVKTVVAAVDVPVTVKTRLGWDDGEINIVEFAQRLQDAGAQMLTLHGRTRAQGYNGRARWQWIAKVKQALTIPVIANGDIFSVEAAIACLEETGADGVMCSRGSLGYPFLVGEIEHFFKTGEKRKAPTVAEKLTCAQEHLQMLWEYKGQRGLFQARKHLAWYCKDFPGAAALREQLFQINSVQEGKDLLDQAISTAKLCL",
    "output": "Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNVLEQLMTYYAQNGSYVMDEFGRHFLMSAYGVLFAAVVGVPAGILIAHFRRLSAWVFAVTNVIQTIPALAMLAVLMLVMGLGANTVILSLFLYSLLPIIRNTYTGIISIEHAYLESGKAMGMTKFQVLRMVELPLALSVIMAGLRTALVIAIGITAIGTFVGAGGLGDMIVRGSNATNGTAIILAGAIPTAVMAVGADLLMAWLERALSPVKKKRTGAKHVQSAA",
    "output": "Involved in a high affinity multicomponent binding-protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKLVFYGAGNMAQAIFTGIINSSNLDANDIYLTNKSNEQALKAFAEKLGVNYSYDDATLLKDADYVFLGTKPHDFDALATRIKPHITKDNCFISIMAGIPIDYIKQQLECQNPVARIMPNTNAQVGHSVTGISFSNNFDPKSKDEINDLVKAFGSVIEVSEDHLHQVTAITGSGPAFLYHVFEQYVKAGTKLGLEKEQVEESIRNLIIGTSKMIERSDLSMAQLRKNITSKGGTTQAGLDTLSQYDLVSIFEDCLNAAVDRSIELSNVEDQ",
    "output": "Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVLAGVAQRPWIKSCDRAFYGSMALSAATTEAPEQTGFWALTLGGIGVVFGDIGTSPLYAFREAVAGAAGGAPASRVLVLGVLSLILWALLIVVTAKYVLLLLRADNNGEGGTLSLMALGRRALGRRSLFLLVLGVIGASMFIGDSMITPAISVLSAIEGLKIAAPALEHYVVPLTVLVLVLLFGVQSHGTAIVARFFGPVMLVWFATLAAMGAMHIMDDPSVLAAINPWYAAQFLASHGTIGLVTLGAVFLAVTGGEALYADLGHFGRRPIQTAWLGFVLPALLINYFGQGALVLSNPAALENPFYKMVPEALVLPLTLMATAATVIASQAVITGAFSLISQAVQLGLLPRFEVRYTSETNAGQIYLPRVNALLLIGVLLLVLLFQTSSRLASAYGIAVSTTMVVDGIMGFVVIWKLWRWSWPAAALVILPLVLVDAMFFSANLLKLLDGAWVPLLFGLAMAVVIWTWRRGVALLMIKSRRAEVPLDDLIGSLEKHPPHIVKGTAVFLTADAEFVPPALLHNLKHNKVLHEHNVILTIETMHTPRVEAADRIRLVKVSEKFSKVALRFGFMETPNVPKALVLARKLGWEFDIMSTSFFVSRRSLKPAAQSEMWRWQTKLFVALAKSANDATDYFQIPTGRVVEVGAQVTI",
    "output": "Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRAWILLLAVLATSQPIVQVASTEDTSISQRFIAAIAPTRTEPSAASAAAAAATATATATATTALAKAFNPFNELLYKSSDSDSDNNNNNYKNRNNNNNNLNKGPRNNKNKGNKHSKSDANRQFNEVHKPRTDQLENSKNKPKQLVNKTNKMAVKDQKHHQPQQQQQQHHKPATTTALTSTESHQSPIETIFVDDPALALEEEVASINVPANAGAIIEEQEPSTYSKKELIKDKLKPDPSTLVEIENSLLSLFNMKRPPKIDRSKIIIPEAMKKLYAEIMGHELDSVNIPRPGLLTKSANTVRSFTHKDSKIDDRFPHHHRFRLHFDVKSIPAEEKLKAAELQLTRDALAQAAVASTSANRTRYQVLVYDITRVGVRGQREPSYLLLDTKTVRLNSTDTVSLDVQPAVDRWLATPQKNYGLLVEVRTMRSLKPAPHHHVRLRRSADEAHEQWQHKQPLLFAYTDDGRHKARSIRDVSGGGGGGGGAGEGGKGNGGGRNRRHQRRPARRKNHEETCRRHSLYVDFADVGWDDWIVAPPGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNLNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGCR",
    "output": "Acts as an extracellular morphogen to establish at least two cellular response thresholds within the dorsal half of the drosophila embryo. Required for the proper development of the embryonic dorsal hypoderm, for viability of larvae and for cell viability of the epithelial cells in the imaginal disks. Acts together with scw (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKRLLILIARAWQLGPSRVLPPSCRYSPSCSQYAIEALEKHGAIKGGWLAAKRLLRCHPWGGHGYDPVP",
    "output": "Could be involved in insertion of integral membrane proteins into the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGQKVHPIGMRIGVIRDWDSKWYAEKDYADFLHEDLRIRDYVAKRLSDASVSRVEIERAANRVNITIHTAKPGMVIGKGGSEVEALRKNLNELTQKRVHINIVEIKRADLDAKLVAENIARQLEGRVSFRRAQKQAIQRTMRAGAKGIKTQVSGRLGGADIARAEHYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPTKKNNVEGGK",
    "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSRIGKQPVSIPSGVECSIKGQLLSVKGKKGQMTLDLHPFTKITSEDGFLKLNPVVEDRDHWAICGTMRALVHNMVVGVTQGFEKKLLLMGVGYRAQAQGQKLTLVLGFSHPVEYAVPQGITIETPTPTEIIVKGFDKQLVGEVAAKIRAYRPPEPYKGKGVRYAGEYVMIKEAKKK",
    "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDKSESTSAGRNRRRRPRRGSRSASSSADANFRVLSQQLSRLNKTLAAGRPTINHPTFVGSERCRPGYTFTSITLKPPKIDRGSYYGKRLLLPDSVTEYDKKLVSRIQIRVNPLPKFDSTVWVTVRKVLASSDLSVAAISAMFADGASPVLVYQYAASGVQANNKLLYDLSAMRADIGDMRKYAILVYSKDDALETDELVLHVDIEHQRIPTSGVLPV",
    "output": "Capsid protein. Probably binds RNA and plays a role in packaging (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS",
    "output": "Small GTPase which cycles between active GTP-bound and inactive GDP-bound states . In its active state, binds to a variety of effector proteins playing a key role in the regulation of lysosomal positioning which is important for nutrient sensing, natural killer cell-mediated cytotoxicity and antigen presentation. Along with its effectors, orchestrates lysosomal transport and fusion . Localizes specifically to lysosomal membranes and mediates anterograde lysosomal motility by recruiting PLEKHM2, which in turn recruits the motor protein kinesin-1 on lysosomes. Required for lysosomal and cytolytic granule exocytosis . Critical factor involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells . In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). Also acts as a regulator of endosome to lysosome trafficking pathways of special significance for host defense . Regulates cargo trafficking to lysosomes by binding to PLEKHM1 and recruiting the HOPS subunit VPS41, resulting in functional assembly of the HOPS complex on lysosomal membranes . Plays an important role in cargo delivery to lysosomes for antigen presentation and microbial killing. Directs the intersection of CD1d with lipid antigens in lysosomes, and plays a role in intersecting phagosomes with lysosomes to generate phagolysosomes that kill microbes . Involved in the process of MHC II presentation. Regulates the delivery of antigens to lysosomes and the formation of MHC II-peptide complexes through the recruitment of the HOPS complex to lysosomes allowing the fusion of late endosomes to lysosomes (By similarity). May play a role in chromosome segregation .; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MWRRKHPRTSGGTRGVLSGNRGVEYGSGRGHLGTFEGRWRKLPKMPEAVGTDPSTSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPAVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSFKRKISVVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKEPEAEPPVPPQVSVEVALPPPAEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR",
    "output": "Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets; ACIN1 confers RNA-binding to the complex. The ASAP complex can inhibit RNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function. Induces apoptotic chromatin condensation after activation by CASP3. Regulates cyclin A1, but not cyclin A2, expression in leukemia cells."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLRKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSGLDTIRQALVRQGDDFKGRPDLYSSTLITDGQSLTFSPDSGPVWAARRHLAQNALNTFSIASDPASSYSCYLEEHVSKEAEALISRLQELMAGPGHFDPYNQVVVSVVNVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPVDFFPILRYLPNPALQRFKAFNQRFLRFLRKTVQEHYQDFDKNSVQDIMGALFKYSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTMIGRGRRPRLSDRPQLPYLKAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKECCVFVNQWQVNHDPELWEDPSEFWPERFLTTDGTAINKPLSEKVMLFGMGKRRCIGEVLANWEVFLFLAILLQQLEFSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIK",
    "output": "A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2. Metabolizes cholesterol toward 25-hydroxycholesterol, a physiological regulator of cellular cholesterol homeostasis. May act as a major enzyme for all-trans retinoic acid biosynthesis in the liver. Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid. Primarily catalyzes stereoselective epoxidation of the last double bond of polyunsaturated fatty acids (PUFA), displaying a strong preference for the (R,S) stereoisomer. Catalyzes bisallylic hydroxylation and omega-1 hydroxylation of PUFA. May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent). Plays a role in the oxidative metabolism of xenobiotics. Catalyzes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin. Metabolizes caffeine via N3-demethylation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPLKRSLKESIERLSSFQSKYNIFTSINPSPYSITNKKGTKETLTGCVASIKDNIVTKDFPTTCASHILENFKSPFDATVVKLLKQAGVHILGKTNLDEFGMGSGGVHSIRGPVINPLYPHEDKKIMGGSSSGAAASVACDLVDFALGTDTGGSVRLPACYGSVLGFKPSYGRLSRFGVIAYSQSLDTVGILSKKINVLRKVFHTLDKYDMKDPTSLSVELRELIEGNKKVRRPLKVGIVKEFSHESMPIGFHRLYLSLLEKLINLGLEIYPVSIPSVKNCLPIYYTLSPAEAASNLSRYDGIRYGYRDSELDIKDGILFAPTRSKFGTEVKNRIILGNYNLCSDAFKNNFIKAEKLRVNLIDEFDGIFRFPNVLTNSKGNPDGLDLLIVPTSSKLPGSIRDFEEEEAKSPANSYINDVFTVPMSLAGLPSLSMPLKEKTPIGLQVVGQYGDDSTVLDFVESIS",
    "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for HMG2-induced ER-remodeling."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTKTVFVLNGPNLNLLGKREPGIYGVATLDDIEASCKREAGQLELQIDFRQSNHEGDLVSWIQEAGEKNAYVLINPAAYSHTSVAIHDAIRSARVTVVEVHLSNIHAREAFRHHSHVSAVAKGVICGFGAEGYLLGLRALAAIAKEEEKNGQSIKGA",
    "output": "Catalyzes a trans-dehydration via an enolate intermediate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "METLSFPRYNVAELVVHIRNKLLTGADGKNLSKSDFLPNPKSDVLYMIYMKALQLVYGVRLEHFYMMPMNIEVTYPHLMEGFLPVRSLFFYMDSFMPICRVNDFEIVDILNPRTNRTSRFLSGIINFIHFRETCLEKCEEFLLQNKSSMVRMQQLSNVHQEALMKLEKLNTVPAEEREEFKQFMDDIQELQHLLNEEFRQKTTLLQEEYAKMKSDISEKTKHLNEQKLSLVSLKEVEDNLKSKIVDSPEKLKNYKDKMKGTVQKLRSAREKVMEQYDIYRDSVDCLPSCQLEVQLYQKKSQDLADNREKLSSLLKESLNLEDQIESDSSELKKLKTEENSLIRMTTVKKEKLATARFKINKKQEDVKHYKQAMIEDCNKVQEKRDAVCEQVTTVNQEIHKIKSAIQQLRDTKKREILKSQEIFVNLKSALEKYHEGIEKVAEERSAKLEEKTAELKKRMVRMV",
    "output": "Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIPELGRRPMHRGNEDSSFGDDYEKEIGVLLGEQQRRQVEADELERELNLFRSGSAPPTVDGSVSAAGGLFSGGGGAPFLEFGGVNKGNGFGGDDEEFRKDPAYLSYYYANMKLNPRLPPPLMSREDLRVAQRLKGSNNVLGGVGDRRKVNDNRSLFSMPPGFEGEKTGASASEWDANGLIGLPGLGLGGKQKSFADIFQADMGHGHPVAQQPSRPASRNTFDENVDSNNNLSPSASQGIGAPSPYSYAAVLGSSLSRNGTPDPQAIARVPSPCLTPIGSGRMSSNDKRNTSNQSPFNGVTSGLNESSDLVNALSGLNLSCSVGLDDRSQAEQDVEKVRNYMFGLQGGHNEVNQHEFPNKSDQAHKATGSLRNSQLRGPHGSAYNGGVGLANPYQQLDSPNYCLNNYALNPAVASMMANQLGNNNFAPMYDNVSALGFSGMDSRHHGRGFVSSGQNLSESRNLGRFSNRMMGGGAGLQSHMVDPMYNQYADSLDLLNDPSMDRNFMGGSSYMDMLELQRAYLGAQKSQYGVPYKSGSPNSHSYYGSPTFGSNMSYPGSPLAHHGMPNSLMSPYSPMRRDEVNMRFPSATRNYSGGLMGSWHMDASFDEGFGSSMLEEFKSNKTRGFELSEIAGHVVEFSSDQYGSRFIQQKLETATTDEKNMVYEEIMPQALVLMTDVFGNYVIQKFFEHGLPPQRRELAEKLFDHVLPLSLQMYGCRVIQKAIEVVDLDQKIKMVKELDGHVMRCVRDQNGNHVVQKCIECVPEENIEFIISTFFGHVVTLSTHPYGCRVIQRVLEHCHDPDTQSKVMEEILSTVSMLAQDQYGNYVVQHVLEHGKPDERTVIIKELAGKIVQMSQQKFASNVVEKCLTFGGPEERELLVNEMLGTTDENEPLQAMMKDQFANYVVQKVLETCDDQQRELILTRIKVHLTALKKYTYGKHVVARIEKLVAAGERRMALQSLTQPQMA",
    "output": "Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs. Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNIDCLCRWVVLPLLRYPLLVALVLRWSLSDSISICLTIYTLLINAFLIANSYIKRSGQVAWKSLREFKNGIVLITGGSKGLGRAIVSQLLQDYSNLTILNVDICPSSVRNTRVKDLICDLSDDEEVAALLNLLKRKYKNEIRLIVNNAGVRANFTGFNGMERDNLDKIFKINTFAPLQFIQELAPSRHSTRQCYIVNIASILGILTPAKVAAYAASKAALIAFHQSYSFELQNEGVRNIRTLLVTPGQLNTEMFAGFKPPRQFFAPVIDITTLAAKIVRYCELGQRGQLNEPFYCSFAHLLMCVPYSLQRIVRSFSRIDCCLPDE",
    "output": "Involved in the resistance to DNA-damaging agents."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAEPSVESSSPGGSATSEDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYDSTVRLPEEEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVTSQDAQEIIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGVCRYKENEKVYENDDQLLWDPECLPEEKVVVFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCSFDTEEALRRLRFNVKAAREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSNSQSEKEDGAVSSRNQNGVSSNGPGEILNKEEVKVEGLHVNGPTGGNKKPLLTDMDTNGYEANNLTTDPKLAHMTARNENDFDEKNERPAKRRRINSSGKESPGSSEFFQEAVSHGKFEEHENTND",
    "output": "Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEKLLDRIDSPADLKKLQVSELTKLAEEIRQEMITVLSKCGGHLGPNLGVVELTLALHYVFDVPRDHFVFDVSHQAYVHKLITGRKNRFHTIRQHGGISGFMSREESEYDCYGAGHAGTALSAALGMAVARDRRGGKEHVIALCGDAAFTCGITFEALNNVASTTQRLIVILNDNEWSIDKNVGAIASYFNKIVTNPAYSYLRDRVEKVLEKWPGKNVLKVARKAEEAFKSLLWPSVIFEELGLTYHGPIDGHDIARLISTFEFLKNQEYPVLLHVITQKGRGFPPALEKQKKFHGLGPYNPITGETPSSPRKTFSEVFAETMIKLADMNRNVVAITAAMPNGTALDKFQPKFPDRYFDVGIAEEHAVIFAAGMATKGFKPYCAIYSTFLQRAYDPIIHDVCLQKLPVVFCLDRGGLSGDDGPTHHGLFDVAYLRTVPNITIMHPKDEDELADMLFTAMHHPGPVAIRYPRGSGSGVAVKERPELIPIGRAEVIKHGRDVAIFSLGIMVEMGKELAQKLEECGYSAALINPRTVKPFDRGTLEFFARSVDLIVSIEDHVLAGGFGSLILEELQALGLRIPVVRIGWPDKFIEHGKVDILRKKYGITVENALEQSLKILKHPKSDTNLEIA",
    "output": "Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKKVIVGTLFALVLVLAGCSSQNSDTKKTGDKLNVVATYSILADIVKNVGGDKIELHSIVPVGVDPHEYDPLPDNIQSAADADLIFYNGLNLETGNGWFDRMLETADKSRDDKDQVVELSKGVKPKYLTEKGKTSETDPHAWLDLHNGIIYTENVRDALVKADPDNANFYKENAKKYIDKLATLDKEAKQKFADLPENQKTLVTSEGAFKYFAARYGLKAAYIWEINTESQGTPDQMKQIISIVEKERVPNLFVETSVDPRSMESVSKETGVPIFAKIFTDSTAKKGEEGDTYLEMMRYNLDKIHDGLAK",
    "output": "This protein is probably a component of a manganese permease, a binding protein-dependent, ATP-driven transport system."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKKVLLVNGPNLNRLGVREVNVYGKGTLATLEADMKQEAEAMGVELECFQSNHEGAIIDRIHEAEDIYEGIILNPGAFTHYSYAIRDAIASISIPVIEVHISNIHQRESFRHESVTAAVCAGQIVGFGFYGYKLALFALMEKLREA",
    "output": "Catalyzes a trans-dehydration via an enolate intermediate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARYIGPKCKLSRREGTDLFLKSGIRPLESKCKADQAPGQAAGASGRRPARLSDYGVQLREKQKVRRTYGVLEKQFRSYYKKAAASKGATGEVLLQLLEGRLDNVVYRMGFGSTRSEARQLVSHRAILVNGQSVNVASYQVKPGDQINVREKSKNQLRVKNAMELAQQRGFMPWIEVDDKKLEGTYKAKPERIDLPAEINENLIVELYSK",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKLHDYYRDQVVNELKTKFNYASVMQVPRIEKITLNMGVGEALTDKKLLDNAVADLTAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFLERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGQALLAAFNFPFRK",
    "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASRKEALARRANRVRRQLKSVANGRPRLSVHRSSKNIYVQVIDDAAGKTLASASTLDKDLRGSLKTGADTAAAALVGKLVAERATKAGVKEVVFDRGAFIYHGRIKALAEAAREGGLSF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLLVLVVLIPVLVSSGGPDGHYEMLGTCRMVCDPYPARGPGAGARSDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDRGPPGPVGPPGEKGEPGKPGPPGLPGSGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD",
    "output": "May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIIGVLSVQGGFVEHMRSIERLGHEARAVRRAEQLEGLDGLIMPGGESTTMSKLLELGGMLEPLRELIADGLPVFGTCAGLILLADRVLDTRSDAHSLHAMDITVRRNAFGRQVDSFETQLPFGDIDTPVEAVFIRAPKVEEVGDGVEVVSTLPDGTVVGVRQGNVLGCSFHPELSEDDRVHEYFLRMVKQRGVE",
    "output": "Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEISALLTSAGINISICIVLLSLYSILRKQPANYCVYFGRRLVCGGARRYDPFWYERFVPSPSWLVKAWETSEDELLAAAGLDAVVFLRMVIFSIRIFFIVAVICIAFVLPVNYYGQPMVHKEIHLESSEVFTIENLKEGSKWLWVHCLALYIITSAACLLLYFEYSTIAKMRLGHITGCASKPSQFTVLIRAIPWSPEQSYSDTLSKFFTNYYSSSYVSHQMVYHNGIIQRLLRDAERMCQTLKHVSPEINCKPSLRPCTFCGGPTATSSFHILSNEADSVKGMELGELTMTTTTTEQERSAAFVFFKTRYDALVVSEVLQSSNPMLWVTDLAPEPHDVYWKNLNIPYRQLWIRKIATLVGAVAFMFVFLIPVTFIQGLTQLVQLSHAFPFLRGILSKNFINQVITGYLPSVILILFFYAVPPLMMYFSALEGCISRSIRKKSACIKVLYFTIWNVFFVNILSGSVIRQLNVFSSVRDIPAQLARAVPTQAGFFMTYCFTSGWASLACEIMQPMALIWNLVAKVVTKNEDESYETLRFPYHTEIPRLLLFGLLGFTNSVIAPLILPFLLIYFFLAYLIYKNQILNVYITKYESGGQYWPIFHNTTIFSLILTQIIALGFFGLKLSTVASGFTIPLILLTLLFSEYCRQRFAPIFNKNPAQVLIDMDRADEISGKMEELHKKLHNVYSQIPLHSQKSSSKAECSNPFKKQELPDPEKLKPEEGDAIAKELWGFQGNESGQEHDTKS",
    "output": "Acts as an osmosensitive calcium-permeable cation channel."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNVNIKTREYTTVTEVSGPLMIVEGVEGVAYSEIVEIETPTGEKRRGQVLEVREDLAVVQVFEGTSDLNTETTKIRFTGETAKIGVSLDMMGRIFDGTGKPIDGGPEIIPEKELDINGSPMNPAAREFPAEFIQTGISTIDGMNTLVRGQKLPIFSGSGLPHNELAAQIARQAKVLAEESEFAVIFAAMGITHEEANYFMRDFERTGALERVTVFMNLADDPAIERIITPRMALTTAEYFAFEHDMHVLVILTDLTNYCEALREISAAREEVPGRRGYPGYMYTDLASLYERAGRIVGKEGSITQMPILVMPQDDITHPIPDLTGYITEGQIVLSRDLHRKGIYPPVDVLPSLSRLMSGGIGEGRTREDHSGVSDQLYSAYAEGRDLRDLMAVVGEEALTERDRKFLKFADEFEKRFITQARDEDRSIEETLNLGWELLSLLPRSELKRVREEHIPKYLPGAE",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLAIGIIRSMKTDDFDFHLPDELIAQFPLANRSDSRMLYVNGKHADLRDAAFRNLPDYLKRGDVIVLNNTRVVKARLSGVKSTGGKVEVMVERILDTHRARVLIRASHALVIGSTLLLENKITAQVEAREQDIYTLCFMHSLPLIELLDQFGHTPLPPYIGRNATVSDENRYQTVFAQESGAVAAPTAGLHFDETMLQTLRTLGVKIIYVTLHVGAGTFQPVRVQNIDQHVMHTEPYHIPTETVEAIQMCKSAGGSVLAVGTTSLRALESCMLTNDGTLVAGAGETNLFITPGFRFRIVDRLLTNFHLPRSTLLMLVSAFAGMETIRHAYRHAIDNHYRFFSYGDAMLIDSQP",
    "output": "Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKFPMVAAALLLLCAVRAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTSEKDEL",
    "output": "Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to disrupt the dimerization of ERN1/IRE1, thereby inactivating ERN1/IRE1. Accumulation of misfolded protein in the endoplasmic reticulum causes release of HSPA5/BiP from ERN1/IRE1, allowing homodimerization and subsequent activation of ERN1/IRE1 (By similarity). Plays an auxiliary role in post-translational transport of small presecretory proteins across endoplasmic reticulum (ER). May function as an allosteric modulator for SEC61 channel-forming translocon complex, likely cooperating with SEC62 to enable the productive insertion of these precursors into SEC61 channel. Appears to specifically regulate translocation of precursors having inhibitory residues in their mature region that weaken channel gating. May also play a role in apoptosis and cell proliferation (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAEEATEFYLRYYVGHKGKFGHEFLEFEFREDGKLRYANNSNYKNDTIIRKEVFLTPAVLKECKRIVSESEILKEDDNNWPEPDRVGKQELEIVLGNEHISFATSKIGSLVDCQSSNDPEGLRIFYYLVQDLKCLVFSLISLHFKIKPI",
    "output": "Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). The MAGO-Y14 heterodimer inhibits the ATPase activity of EIF4A3, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation. The MAGO-Y14 heterodimer interacts with the EJC key regulator PYM leading to EJC disassembly in the cytoplasm (By similarity). Can increase in vitro the expression from reporter constructs that contain leader introns required for the expression of different genes. In association with MAGO and PYM, participates in intron-mediated enhancement of gene expression . The MAGO-Y14 heterodimer works synergistically with the NMD pathway to regulate male gametophyte development ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTVLLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVRSGQSAAAARDVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSGLAHLHGDVAVLIPTTT",
    "output": "Toxic component of a type II toxin-antitoxin (TA) system. Its cognate antitoxin is VapB29. Has ribonuclease activity (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRADIHPKYEKLVATCSCGNVIETRSALGKETIYLDVCSACHPFYTGKQKNVDTGGRIDKFKQRFAGMSRSIKR",
    "output": "Binds the 23S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "QHSTDYDEEEEDRAKLHLDAR",
    "output": "Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADLKQVYHDKVVPELQAKFGYSNVMQVPRLQKIVVNMGVGEAIADKNFLNNAIGNLEAITGQKAQTTYAKKSIAGFKLREGQAVGCRVTLRRRQMWEFLDRLINAALPRVRDFRGVSEKAFDGRGNYTMGIKEQIIFPEIDYDKVDKVRGMDICIVTSAKTDDEARQLLAGFNMPFRKKEGNNG",
    "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKMEVKSSLLDNMIGVGDMVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLYKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFLDHEAEAVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTSIDQVVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTTLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHSLIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMRNLQTKNPNYIRCIKPNDKKAAHIFNESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEHSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKRSQVVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCKEAATTIAAYWHGTQARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYLLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP",
    "output": "Motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMALGEPYYSSKPDKDFNFGSTMARRQMTPTMVTKLPKFVRNSPQAYDWIVRGLIFPTTGKTYFQRVVVITGGLEDGTYGSYAFNGSEWVEIYPIEHLNLMSSLKLIHKANALQERLRLSQEEKATLALDVQFLQHENVRLKELIPKPEPRKIQMKWIIVGAVLTFLSLIPGGYAQSQTNNTIFTDMIAACKYSTETLTENLDLRIKLALANITINDKLDAVRQILNFAFVPRAHWLRTVFYYIHYYEMWNIFMFVLAIGTVMRSARPGTDLITLATSHLSGFRMAVLPTIPFHTTMTLWVMNTLMVCYYFDNLLAITMAILAPILGIIFLCFMEDSNYVSQIRGLIATAVLIAGGHACLTLTGTTTSLFVVILTCRFIRMATVFIGTRFEIRDANGKVVATVPTRIKNVAFDFFQKLKQSGVRVGVNDFVVIKPGALCIIDTPEGKGTGFFSGNDIVTAAHVVGNNTFVSVCYEGLVYEAKVRYMPEKDIAFITCPGDLHPTARLKLSKNPDYSCVTVMAYVNEDLVVSTATAMVHGNTLSYAVRTQDGMSGAPVCDKYGRVLAVHQTNTGYTGGAVIIDPADFHPVKAPSQVELLKEEIERLKAQLNSAAENPVTVVTQQPIVTLEQKSVSDSDVVDLVRTAMEREMKVLRDEINGILAPFLQKKKGKTKHGRGRVRRNLRKGVKLLTEEEYRELLEKGLDRETFLDLIDRIIGERSGYPDYDDEDYYDEDDDGWGMVGDDVEFDYTEVINFDQAKPTPAPRTTKPKPCPEPKIEAQPLDLSQKKEKQPEHEQQVAKPTKPQKIEPQPYSQTYGKAPIWESYDFDWDEDDAKFILPAPHRLTKADEIVLGSKIVKLRTIIETAIKTQNYSALPEAVFELDKAAYEAGLEGFLQRVKSKKQGPKKLQRAPEDQGAQNYHSLDAWKSLLEPPRERRCVPANFPLLGHLPINRPIFDDKKPRDDLLGLLPEPTWHAFEEYGPTTWGPQAFVKSFDKFFYAEPIDFFSEYPQLCAFADWATYREFRYLEDTRVIHITATEKNTDSTPAYPKMNYFDTEEDYLEAHGWAPYIREFTRVFKGDKPEVLWYLFLKKEIIKEEKIRNSDIRQIVCADPIYTRIGACLEAHQNALMKQHTDTSVGQCGWSPMEGGFKKTMQRLVNKGNKHFIEFDWTRYDGTIPPALFKHIKEIRWNFINKDQREKYRHVHEWYVDNLLNRHVLLPSGEVTLQTRGNPSGQFSTPMDNNMVNFWLQAFEFAYFNGPDKDLWKTYDTVVYGDDRLSTTPSVPDNYEERVITMYRDIFGMWVKPGKVICRDSIVGLSFCGFTVNENLEPVPTSPEKLMASLLKPYKILPDLESLHGKLLCYQLLAAFMAEDHPFKVYVEHCLSRTAKQLRDSGLPARLTEEQLHRIWRGGPKKCDG",
    "output": "[Non-structural polyprotein 1AB]: Contains the viral protease participating in the cleavage of the polyprotein into functional products. It contains also the activities necessary for replication of genomic RNA, as well as transcription of subgenomic mRNA.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAASTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC",
    "output": "Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKLQLVAVGTRMPAWVTTGFEEYQRRFPRDMAFELIEIPAGKRGKNADIARILQKEGEQMLAAIPKGNHIVSLDLPGKNWTTPELATQLNRWQLDGRDVSLLIGGPEGLAPACKQAANQSWCLSALTLPHPLVRVLVAESLYRAWSINNNHPYHRE",
    "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKIVKFGDEARQKMLAGVNVLADAVKTTLGPKGRNVVLDKSFGAPTVTKDGVSVAKEIELEDKFENMGAQMVKEVASKASDDAGDGTTTATVLAQAIVNEGLKSVAAGMNPMDLKRGIDKAVNAAVAHIKSIAQPCEDGKSIAQVGTISANSDSHVGDIIAEAMAKVGKEGVITVEEGSGLENELDVVEGMQFDRGYLSPYFINNQESMSVEIEQPYILLVDKKISNIRELLPVLEAVAKSGKPLVIVAEDVEGEALATLVVNNMRGIVKVTACKAPGFGDRRKAMLQDIAILTGGTVISEEVGLDLESATLEHLGSAKRVTMTKENSTIVDGAGVAADIESRVAQIRAQIEETSSDYDREKLQERVAKLAGGVAVIKVGAMTEVEMKEKKARVEDALHATRAAVEEGVVPGGGTALIRAAAAIADLKGDNEDQNAGIGIAIRALEAPLRQIVSNAGGEASVVADKVKNGEGNFGFNAASGEYGDMLEFGILDPAKVSRTAIQAAGSIAGLMITTEAMIADKPSEGGAAAPDMGGMGGMGGMGGMM",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSGRGKSGKARTKAKTRSSRAGLQFPVGRVHRFLRKGNYAKRVGGGAPVYMAAVLEYLTAEILELAGNAARDNKKSRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTAKSS",
    "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNSFRKTCAGALALIFGATSIVPTVAAPMNMDRPAINQNVIQARAHYRPQNYNRGHRPGYWHGHRGYRHYRHGYRRHNDGWWYPLAAFGAGAIIGGAISQPRPVYRAPAGSPHVQWCYSRYKSYRASDNTFQPYNGPRKQCRSPYSR",
    "output": "Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSRQKKSRNIVDVMPQRKSDKSQISPASYARPSKKLTRYELDAKAREDKKKKKHKGLTSGSRHSRSEQHNNQQMQEKRDPRLGSRKKVPLVVEFVNNPEKGQFIQPVQVQPAEEKVKKLDPMLELEQLENNECLNQLLDALDEGKTISAEDQKFVDECLDRIAQLMDELGIEDEEESEDDLLRTFEKIDINQFK",
    "output": "A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAYQKVECQFNGQTLTLETGKMARQADGAVVVSFGGTKVLCTAVSAKQMREGQSFFPLTVNYQEKFYAGGKIPGSFFRRERGATERETLVCRLIDRPLRPLFPKGYMFETQIMPTVISVDEQNDPDTLAMVGASAAIAVSDIPFDGPVAAVRVGRVEGNLIANPTIEQRAESDMDIIVSGSRDAIIMVEGETRFISEQEMLDALFFAHEAIQPLIDVQLELVKIAGKEKREFSVPEIDPAVVEKVAELAETRLSEAVKIRTKQDRYAAVAEIKTEILETLAADFEDQEDDISEAFGNLQKRLVRQMVARDKVRIDGRDKNTIRPITCEIGLLPRAHGSALFTRGETQALVAAALGTSKDEQRMDNVQSMEFKKFMLHYNFPPFCVGETSMRLFPGRREIGHGMLAERSIAQVLPNHDDFPYTLRVVSDILESNGSSSMASVCGASLALMDAGVPVSEAVAGIAMGLIKEGDDIVVLSDILGDEDHLGDMDFKVTGTREGITALQMDIKIKGVSKEIMQQALEQAREGRLHILDKMAEAITAPRSDLSPYAPRITTIQVKPDQVRTVIGPGGKNVRGIIEATGCAIDIEDDGRINIASADGDACKAAIKMIRNLTQEAVVGKLYMATVKKIMEFGAFVEIFPGTEGLVHISELAKERVKKVTDILQEGDQVLVKCLDIDRQGKIKLSRKEALGQSLPEEG",
    "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRASRFLFATLRETPNDAEVISHQLMLRAGMIRKLASGLYTWLPMGVRVLNKVEAIVREEMNRSGALEVFMPVTQPASLWEESGRYVQYGPELLRFKDRHDNPFVLGPTHEEVITDLARNELKSYKQLPINFYQIQTKFRDEIRPRFGVMRSREFIMKDAYSFHVDQASLQETYDNMYDTYCRIFTRLGLDFRPVQADTGSIGGSGSHEFHVLADSGEDDIVFSTESDYAANVEKAEAVLVGERAAPAQALSIVDTPNQKTIADVCTFLNADPKQSVKALLVQGNADEKGNVPVIALFLRGDHELNEIKAEHHPLIAAPLTFATEAQLQELGLTAGYVGPQGLVEKGLTVIVDRAASVLSDFIAGANEADKHATGVNWERDAKFSEIYDLRNVVDGDPSPDGQGVLQIKRGIEVGHIFQLGQKYSEALNCTVLGDDGKPLVVTMGCYGIGVTRVVASAIEQNYDDKGIIWPSAIAPFEIAIVPMNAHKSPKTLEAAEALYAELQAQGYDVLLDDRNERPGVKFSDLELTGIPHRIVIGEKGLDAGTFEYKGRTDAESVNLTKDELLAKLK",
    "output": "Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKHIPVLEDGPWKTVCVKELNGLKKLKRKGKEPARRANGYKTFRLDLEAPEPRAVATNGLRDRTHRLQPVPVPVPVPVPVAPAVPPRGGTDTAGERGGSRAPEVSDARKRCFALGAVGPGLPTPPPPPPPAPQSQAPGGPEAQPFREPGLRPRILLCAPPARPAPSAPPAPPAPPESTVRPAPPTRPGESSYSSISHVIYNNHQDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLDYSADHSNLSFSECVQRCTRTLQAEGRAKKRKE",
    "output": "Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins . Regulates endothelial cell proliferation, migration and tube-like structures formation . Modulates endothelial cell differentiation through NOS3 . May be implicated in specification and differentiation of neuronal cell lineages in the brain (By similarity). May participate in kidney development and may be involved in podocyte differentiation (By similarity). During early embryonic development is involved in tissue-specific differentiation processes that are dependent on class II bHLH factors and namely modulates the differentiation program initiated by the pro-endocrine factor NEUROG3 (By similarity). During myogenesis, may play a role during the transition of myoblasts from the proliferative phase to the differentiation phase (By similarity). Positively regulates HAMP transcription in two ways, firstly by acting directly on the HAMP promoter via E-boxes binding and indirectly through increased phosphorylation of SMAD protein complex . Repress NEUROG3-dependent gene activation in a gene-specific manner through at least two mechanisms; requires only either the sequestering of a general partner such as TCF3 through heterodimerization, either also requires binding of the bHLH domain to DNA via a basic motif (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKKVYHYIIHYVRTYLLLELLAGLWLTVKYFFRKKITVQFPEEQTPLSPRFRGLLALRRYPNGEERCIACKLCEAVCPALAITIESEQREDGSRRTTRYDIDMFKCINCGLCEESCPVDSIVVTPIHHYHISERGQNIMTKEKLLAVGDLMETQLAADRAADEKYR",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFQIPVQNLDNIRKVRKRVKGILVDIGLDSCKELMKDLKSFDPGEKYFYNTSWGDVSPWEPSGKKARYRTKPYCCSLCRYSTKVLTSLKNHLHRYHEDEADQELMIPCPNCPFSSQPRVVGKHFRMFHAPARKVQSYTVNILGETKTSRSDVISFTCLKCNFSNTLYYSMKKHVLVAHFNYLINSYFGLRTEETGEQPKASDPVSVDKILPFDKYYCKKCSAIASSQDALMYHILTSDAHRDLENKLRSVISEHIKRTGFLKQMHIAPKPVTHLALPPNSSAPSIAAPPPCFQLALPQNSQSSGTVQSVTVTPGTSGSLTHSPPTTAQSHVALVSSSLPVCQSSLSLQQSAPPPVFLSHSVALNQPVNTAVLPLTQPVGPVNKSVGTSILPVNQAMCSVNQAVRPGLLPLTKPMGPMNRPVGPAVLPMGPSVNSGVLQATSPGVISVGRAVPSGVLPAGQVTPAGVIPGQTATSGVLPTGQVVQSSTLPVGQTAPSRGLPPGQTVPLRVLPAGQVVPSGLLSSNQTVPSGVVPVNQGVNSGVLQLGQPVTPGVLPVGPPVRPGVLQLSPSVSTSILPMSQPVRAGTSQNTTFFTSGSILRQLIPTGKQVNGIPTYTLAPVSVTLPVPSGGGLAAVGPPPQVPVQFLPSGSGTQMGSSLPSLPSPQVLVSPAPSVFVQATPPLADANQALKQAKQWKTCPVCNELFPSNVYQVHMEVAHKQSEAQLCQVCNELFPANVYQVHMEVAHKQSESKSSEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSQEELMHHLLMHGLGCLFCPCTFHDVRGLVEHSRTKHLGKKRLSMDYSNRGFQLDLDANGNLLFPHLDFITILPREKLGEREVYLAILAGIHSKSLVPVYVKVRPQPEVAPKIPNKQKLTCPFCLSTFMTADAYELHLKERHHVMPTVHTMLRSPAFKCIHCCGVYTGNMTLGAIAVHLLRCRSAPKDSSSDLQVQPGFIESSELLMVNGDVIPESTFPVKRKLPEGHLGPEDQRDGEEPQLTLDADASSGSEKGLGAVPLKRQKSEIRTEGSGPSEDSLQALALDPSKYEGRSYEEKKQFLRDYFHRRPYPSRKEVELLSSLLWVWKIDVASFFGKRRYICMKAIKTHKPSVLLGFDMSELKNVKHRLNFGECESQKL",
    "output": "May be involved in transcriptional regulation . May play a role in neuronal function; perhaps involved in protection of brain tissues from oxidative stress . May be involved in erythroid differentiation ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MMDFLKRFFGSSQERILKRFQKLVEEVNACDEKFSSLSDDELRKKTPQLKQRYQDGESLDKLLPEAYGVVKNVCRRLAGTPVEVSGYHQQWDMVPYDVQILGAIAMHKGFITEMQTGEGKTLTAVMPLYLNALTGKPVHLVTVNDYLAQRDCEWVGSVLRWLGLTTGVLVSGSPPEKRKAIYQCDVVYGTASEFGFDYLRDNSIATRKEEQVGRGFYFAIIDEIDSVLIDEARTPLIISGPGEKHNPVYFELKDRVAELVYFQREMCNHIAIEARKVLDPFLGTDVLPKDKKVMEAISEACRALWLVSKGMPLNRVLRRVREHPDLRAMIDKWDVFYHAEQNKEQCLEKLSSLYIVVDEHNNDFELTDKGMLQWIEKIGGAAEDFVMMDMGHEYALIEEDATLSPADKLNRKIAVSEKDTQRKARAHGLRQLLRAHLLMEKDIDYIVRDDQIVIIDEHTGRPQSGRRFSEGLHQAIEAKEHVTIRKESQTFATVTLQNFFRLYEKLAGMTGTAITESREFKEIYSLYVLQVPTFKPCLRIDHNDAFYMTEREKYQAIVAEIISAHRSGKPILIGTESVEVSEKLSRILRQNRINHTVLNAKNHAQEAEIIAGAGKVGAVTVATNMAGRGTDIKLDEEAVAAGGLYVIGTSRHQSRRIDRQLRGRCARLGDPGAAKFFLSFEDRLMRLFASPKLNTLIRHFRPPEGEAMSDPMFDRLIETAQKRVEGRNYTIRKHTLEYDDVMNKQRQTIYAFRNDVLHAEDLFVVAKEQIEHVALALAFLILKDAHADHCSLPKIEEWLSYSFPVKLDDQEIRRLGDVDAVADYIGDLLIEAFDVKFSAMLAEFTEIIGSAANAQGICNDILRSVIISHIDEEWKVHLVDMDLLRSEVGLRSVGQKDPLIEFKNESFLLFEGLIRDIRIAIVKHLFALELSLTRSDRPDNAIPTVATAFHNHDNFRPMELTIVGEEEES",
    "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSTISATVAGPSIVQFVQIDSLVVMKIVKHVDSEMYAGLNEVAGEACQGLLTGLVSIDDRRLEITNCFPTARAEPMLDGDEIAQNNAFYEEQKQAEMLDMLRKFRDMNIDYELVGFYQAHPFGACFAQETIDSLIDYQASVPDGVVLIYDPVKTRQGQLSIRAYRLSTKALEMSLDGDWSPESTRTAGLTYENMLEELPVVIKNSHLVNVMLAELALEGDCAIQRSSSHLELGTRRSLEKCLRSLMSDVDDLNRTVMAYTKYVADKQRYDLTVYNAMQKRQAENEQREARGEPPLSFDDIKKMKPPQLTTKCGMLESFLCSSDARAHSDYAAEACLRHFSFSSFCLCFFNENIAKLFLAEAVVDSHGSRDHGGAAASVR",
    "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIVGQYFGWRMTFFAIGIGALVTLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLEEQTQ",
    "output": "Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "RPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREITRQQGEKFAHEITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDILRNELSNSILSLQPEPEIPPELPPPRPHVRCC",
    "output": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQQILEHIVGIANDLLWSKLLIVLLLSFGIYFTFRLKFLQVRMLKEMVRVLREGAASRSKNSISPFQAFCISMAARVGTGNITGIAIAIALGGPGAIFWMWIIAIIGSASSFVESTLAQIYKVKDVNGFRGGPAYYMEKGLNKRWMGALFAVLITLSFGIVFNSVQSNTVSLAFENAFGTNRLTLGLILIAVFGTIIFGGVKRIAKLAESIVVVLAVLYIGVAFFVIFSNITQLPGVLALIVKNAFGFDQAAGGALGAALMQGVRRGIFSNEAGMGSAPNAAATATTSHPVKQGLIQAFGVLTDTLVICTSTAFIILFSDAYHTPGLSGIALTQASLSSHVGSWASGFLAILILLFGFCALIGNYYYGETNIGFLNKSKKLIFVYRIGVLAMIVFGCVAKVQLVWDLADLFMGLMVIVNLIAIFLLSKVVFTALKDYTRQKKAGKDPVFYKDVLKNHNGIECWPVSDTKTDTHNKQIS",
    "output": "Probably functions as a sodium/glutamine symporter for glutamine uptake."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVKQVSDSSEFKSIVCQDKLVVVDFFATWCGPCKAIAPKFEQFSNTYSDATFIKVDVDQLSEIAAEAGVHAMPSFFLYKNGEKIEEIVGANPAKLEASIKANL",
    "output": "Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRLVFAGTPAVALPSLRALLDSPRHQVVAVVTRPDRPAGRGRHQRSSPVRELADERGLEVLAPARASDPDFLARLGEIAPDCCPVVAYGALLPRPALDIPKHGWVNLHFSLLPAYRGAAPVQRAVLAGEDMTGASVFEIEPALDSGPVYGVLTERIRPTDTSGDLLDRLAVAGARLLEAVMDGIEDGTLQARPQPSDGVSLAPKLTVEDVRVDWSAPAAAVDRLVRAATPAPGAWTTFRDRRVKLGPVRPAPAGHPPLPSGRLAAPERGLVLVGTATTPVVLDEVRPEGKAPMPAADWIRGLRPGTDEAFA",
    "output": "Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEKLSEKDKELIRGSWESLGKNKVPHGVVMFSRLFELDPELLTLFHYTTNCGSTQDCLSSPEFLEHVTKVMLVIDAAVSHLDDLPSLEDFLLNLGRKHQAVGVNTQSFAEVGESLLYMLQCSLGQAYTAPLRQAWLNLYSIVVAAMSQGWAKNGEDKAD",
    "output": "Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Capable of penetrating cell membranes (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEQTLAQAVSRRGKTNTPMAEERKPFSPMNFSANFVAPELFYSANVRKIKNIFRERSTTRFLDAISSDFELVAFLTLSPAHLMQLETTLRQEIRSCVVPIVTSDASFETVAVIKTALDGMRFHFGHTTLEKGWMSMMRHAESCLQESSSSAVNDLQMQIKRVGSLLLSGKNRVESCELSVLNLTARRFRIEYGLNGTYFGEHVAMLLDLKRYIYGTVPKEFCWAKTKKHSLFTTPKWIKRTPIDCFLFCLRVIPILHRFGVAISLLYWSCVAALNFPAFMAFLFKRQFAKYLAHSFAKHSIYFIFLTIIAILWSFRTFASQKPKIVLQARSTAEKEKKLMMILASVVGITYLFDYDIAEALGNCLHKISRLSSYLLDDHQGIASRMFGASYGLQAGDSAEDAVTTIISDLLSVTFKIVDEDASQGTVEDASETTFHSWVGVNTLAGRNMSRPLQYDVNKTYALTPQNVQLQARAMADANNCWSMVVGHTGSGKSTYLPVQYSNYLSTKSDRRQQILICEPTQAATENVCAGVAANLGRAVYGRHEGWSRMGDHCIQVMTYGSALQCHAMDPSFISTFDAIFLDEAHDVKEHSLVFESICDTFKSVRKFYVSATPRDGSVCPEAARKYPLHVETSVCDSYRKFIAAQGGGDLLDISKHDTALVFLAGRPECIKAANAWNASVTGEKRAFPLSSDNFATDFSMLTERLKTHKTIIFTTNIIETGVTLSVDCVVDFGHTMRPCLDLNQKSLRLDRRRVTRNERQQRIGRAGRLKDGYAIVCGDVDRAVNVISPDVLYGAALLSFKHNVPFYMNETFESSWLEGVTKAQADTMTIFKLPIFLTRDLINADGSVAREFLDVLKKHQFTTSDIKQAPSVTAKHIFPTWASYFSLHQALHYGDDKDEIPHELRYARVPFSVTTLSKFDWPALALACEKHRASMSNVFAGIEEPARVVTLQTNPANIQASITHLTHMSKNYKTLIENNQHVRQSMMTNVMFKWFSSTRITKDLDRNLRRCTDNLSVVEATLSSLRQILAGNTQVHATPHMQSTLEDIIELQASDTLTEESLANALGIFVPKCNLFLLLATKGFKLVYVVCILLLVNLVYTGLRKWREHLKQKGSNEILTNTMPVSEGGEILAEVMKMEPKMRKNIKRDMDAAVESKLCGFTFVFPDDDKIGLEGKGNKYRPREDARLMYSTREDATFDAWNEKAKERRKKVTDKAEPELRRAYEKRPYFNFYDLQTDSNILEAIFYTTEGDEFFRTADPNRDMNLVADKLRSFLDTKLVVGHHQRKLLEETANVVIKDTKGTAHKMEISQHDPDFLKQNGSGKVGYPEHRGQFRQEGVAVTGDYDLEAEFGTDTDEISFGASTGILLSQVGVDVATRVGRICIGTFNMNCYFYSDWILVPGHLQDRSGNVTIQFPDQTVQTTTDALNANGVKRFYGLDVIAIRRPAILRPRTKLVKAFAIEEPVIAQMVFVDAQGVRKFTQSDWARKEENSGRWSHKISTVLGMCGCPVLDVGKNRLIGIHVATNYTKKRNEFQPFTQEVVDFINGPGTKIPYCPWVFDRPACGYSSHNALFEKPTTLADVIHMQASDGLHNINNAIEGFGSSLKGQLVSPPTESTRQRFDKLFGSGSFELIGQMNKGLIDKHVIVGENDDVYDFMREHPTFTWLKDFMNEYAPSVLSYSAYYKDLCKYNRAKHVLTYNPEELHCATKGLIKMLEDAGLTQGSVRTPQQVVSDIQWNTSAGPSYQGKKRDLCAHLSDDEVLHLAEVCRQQFLEGKSTGVWNGSLKAELRTIEKVEAEKTRVFTASPITSLFAMKFYVDDFNKKFYATNLKAPHTVGINKFGRGWEKLHDKLNRPGWLHGSGDGSRFDSSIDPFFFDVVKTIRKHFLPSEHHKAIDLIYDEILNTTICLANGMVIRKNVGNNSGQPSTVVDNTLVLMTAFLYAYIHKTGDRELALLNERFIFVCNGDDNKFAISPQFDEEFGHDFSPELVELGLTYEFDDITSDICENPYMSLTMVKTPFGVGFSLPVERIIAIMQWSKKGGVLHSYLAGISAIYESFNTPKLFKSIYAYLLWLTEEHEAEILAAMTQSSTALPIPSMLDVYRLHYGDDEIWLQAADPLTDAQKEAAHTAAADRARLDLADADRRRKVEADRVEAARVKKAADAVLKPVTLTATRMPTEDDGKLKTPSGARIPSSAADGNWSVPATKQVNAGLTLKIPLNKLKSVPKSVMEHNNSVALESELKAWTDAVRTSLGITTDEAWIDALIPFIGWCCNNGTSDKHAENQVMQIDSGKGAVTEMSLSPFIVHARMNGGLRRIMRNYSDETVLLITNNKLVAHWSMKHGASANAKYAFDFFVPRSWMNPQDIEVSKQARLAALGTGTYNTMLTSDTTNLRKTTNHRVLDSDGHPELT",
    "output": "[6 kDa protein 1]: Indispensable for virus replication.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVLNLDTENRKMQDGNNDDDFDLEVQIPNSIFEKLKSIEALKARESPMCVSGKDDSIPTCDQNSTPGMITQRSCVYGGARVVLMPITDAVHLVHGPIGCAACTWDIRGSKSTGDKLYKNGFSTDLQEKDIVFGGEKKLYESILEVNKLYHPGAIFVYSTCVVGLIGDDLKAVCRQAQEATGCRVIPVQSEGFKSFNKTAGHKLACDAMLDYVIGTEEPEEEHPYSINIIGEFNVAGDLWGIIPLYEKMGVKVHTAITGDSTVAKVASAHRSKLNIVQCPKSSNYLAAQMDKKYGIPSFKVNFFGLDETTKSLRAVAEFFGDEEMIKRTEELIKSEIKNLRDEISEYQKDLSGRTVAIYSGAHKSWALVSAFGELDMEIIMSGTQNGKPEDYQQIRDHVCEGTLIVDDASSMELVQLLKEYKPDILISGAKEKYLSLKSGIPHCDFNHDRITAFSGYQGFINFARVVHTAVMTPIWRLSRKMMI",
    "output": "This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFIDKGASPLPIREAKMQKTAYYENSGLFGGYTYAKPESYSYGPSQQQYPQSSLDNDYPSTACSVQPAAIRAPNHKTNDISNSCMRTTSSQNSNQTPSISNQQHQAPSLPPSSPSHSNTSAQKKSKSSNSSGSSQSTMNKQIFPWMKESRQNSKQKNSSSTPPAGENCEEKSPTGPSSKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGIMHSPTGQSPDRSPPLSGPNLVGYSSQLPTVNSLSYDAPSPTSFAKSQQNMYGLAAYTAPLSSCLPQQKRYPGAEYEHHTMQGNSGFANPNLQGSPVYVGGNFVDSMPASGPMFNVGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSSHHTTQGRMQEAPKLTHL",
    "output": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVNEIDSESLSQRLADTEDVLLVDIRTPAEIAQGMIPDALQLPMHLIPIRMSEIPKDRDVVIYCRSGARSYQACAYLMQQGYGRVLNLRGGIIAWARHGLPIVAPEG",
    "output": "Sulfur carrier protein involved in sulfur trafficking for oxidative dissimilatory sulfur metabolism. Component of a sulfur relay system that starts with the sulfur-mobilizing rhodanese-like protein Rhd_2599 (Alvin_2599), which transfers the sulfur from a low-molecular-weight thiol, maybe glutathione, to the TusA protein (Alvin_2600); TusA serves as the sulfur donor for DsrEFH, which persulfurates DsrC; persulfurated DsrC very probably serves as a direct substrate for reverse-acting sulfite reductase, DsrAB. Is able to catalyze the sulfur transfer reaction from thiosulfate or glutathione (GSSH) to cyanide in vitro, however, thiosulfate is unlikely an in vivo substrate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDFVIQWSCYLLAFLGGSAVAWVVVTLSIKRASRDEGAAEAPSAAETGAQ",
    "output": "Required for wild-type expression of ArfA and ammonia secretion."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEEGSNKREGLPPQLLDLIPDEKEWKLREALGLGRSRNAGFDGEEDKKLDLKLGLPGFIEDDEAETLRDYRLQQESPSLSLSFFPKHSKTTSSTTTTTGAKRGFIDTVEDKTEGYNDQKQQARAGCGKELAVEEMIAAVSERKKGCCPPPPPPHGAPATPARNRPQTQGRGAAAPVVGWPPIRSFRRNLASSSSSKHSPEPQNDNANAKVTLTCKKNPLVKINMDGIPIGRKIDLAAYNSYDGLSSAVKQLFHGFLQAQKDQTNAQIAQQGADDKIFYQLLDGSGEYTLVYEDSEGDRMLVGDVPWKVFVSTAKRLRVLRSSELSHTLIGATARV",
    "output": "Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATDELASKLSRRLQMEGEGGGEAPEQPGLNGAAAAAAAAGAPDETAEALGSADEELSAKLLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKEYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLHVLARLSEIDVSTEGVKGAKSFFEAKVQAMNVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQSTFK",
    "output": "May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSTNLSNAEILNNLLEGRDLDELTSRALMQRWLNDEISDVETGAFLSALRAKSSTGVELSSMAKELLNVCELPVARPNLYLVDTCGTGGDGANTFNISTAVAFVAASCGVKIAKHGNKSASGKVGSADVLLNLGLNLNCSLEKVINAVSEIGITFLFAPVWHKSLIKLAPLRKTLGIRTVFNQLGPLVNPLRPNAQVLGVASEDLLQPMGSALLNLGMNRAIVVHGSGGLDEASLQGKNKLVFIENGELRFSEINISDFNHENIANENLVVSDLDSNEEILKSVLNGSGQKSHMDVVALNVSLVLWAAGIEDNLNEGFNKALFSINKGDPWKKFLLLKNYLSAN",
    "output": "Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRPSRRAPDELRAVSLERGVVKYAEGSCLVKFGDTHVLVTATLEERLPPWLKGQGRGWVTAEYGMLPRATLERTRREAAAGKQNGRTVEIQRLIGRSLRAIVDLQALGERQITVDCDVLQADGGTRTASITGAWVALADCLGWMKTRNMIKGTVLRDNVAAISCGIYNGTPVLDLDYAEDSEAETDANFVMTGDGRIIEVQGTAEKTPFSQDEFLALMALAQKGVTRLVDLQKMAVA",
    "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISKYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGETKGMIY",
    "output": "Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKKFSSKTIKAKNSVKMTALSTRAIAANLILQVLDEGKSLSALIPEVQLSVKAQDLPLLQEICFGVCRVLPRLEQIIKRLVDKPLKGKTRIVHCLLLVGLYQLLYMRVPAHAAVDEVVNATKSLKSDSFRGLVNAVLRRFLREQDEILAIIDKNWQTLHPEWFVNKLKKAYPNWREIIEANNQKPPMWLRVNSQKNALETYRTLLEEQGVSSKTSHHPNALCLDIPIAVQKLPHFEEGAVTVQDLSAQWAATLLEPKNEEWILDACAAPGGKTTHILELAPQANVIALDVESHRLKRVEENLERLNQQAIVVCGDASKPDEWLAEIGKSAAKFDRILLDAPCSATGVIRRHPDIKWLRKETDIAQLVELQKKILSALWEKLKPNGVLLYATCSVLPEENCEQIQAFLNAHADAELLSLPFSDDKSAVGFQFIPQPNSGDGFYYAKLLKRAS",
    "output": "Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTNIRKSHPLFKIINDSFIDLPAPSSISSWWNFGSLLGVCLAVQILTGLFLAMHYTSDTATAFYSVTHICRDVNYGWVLRYLHANGASMFFICLFLHVGRGIYYGSYTFSETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWVWGGFSVDKATLTRFFALHFLLPFIISAMVMVHLLFLHETGSNNPTGIPSDVDMIPFHPYYTIKDILGLVLMLMALLSLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVVALVLSILVLAVIPLLHTSKQRSMTFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFLIILVLMPLASIAENHLLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSRKGSTPQRTVLPDPKHGSETIARFINMVMQSGKKSVAEKIVYGAMDVIGEKNPNAIELVQKALDNVAPAVEVKSRRVGGATYQVPVEVRSSRRMALAMRWLIDSARKRGENTMPRKLAAELLDAAESRGGAIKKREETHRMAEANKAFAHYRW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDYVNVVDGSKKTMNSPEGAAPGLIGATGITNPTPDNDLPLQASNKLTRLSQSTSNDSKLIAAGEPKACDLERSRVGGSCKMTTPGHSNFVLKRDSVEGCPAKNSSMAESNGQTNPMHCRIVPLQSAEGDTNQGFGKNSLEQNNAKGDWVPISQSTVVLGTDGNTSVFPGTLTGDEEGDENKARGNWSNKLDFILSMVGYAVGLGNVWRFPYLAFKNGGGAFLIPYLTMLALAGLPIFYLEVALGQFASQGPISVWKAIPALQGCGIAMLIISVLIAIYYNIIMCYTIFYLFASLVYVLPWASCNNPWNTPDCKDKDRLLLDSCIISSQPNIQIKNSTFCMTAYPNLTMVNFTSHGNKSFVSGSEEYFKYNMLKISAGIEYPGEIRWPLVFCLFLAWIIVYASLAKGIKTSGKVVYSTATFPYVVLVILLFRGVTLPGAGDGIWWFIMPKWEKLMDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNLYRDTLIVTCINSATSIFAGFVIFSVIGFMAHILNVDIEKVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSVSDEFPKLLRTHKPLFTLVCCVAFFIMGFPMITQGGIYMLQLVDNYAASYSLVIIAIFELVGISYIYGLQRFCEDIEMMIGFQPSRFWKICWAFVTPTILTFILGFSFYQWEPMTYGSYHYPSWSMVMGWLMLACSVIWIPIMFVIKMFLAPGTFIERLKLVCSPQPDWGPFLAKHRGERYKNMIDPLGTSSLGLKLPPKDFELGTQC",
    "output": "Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSDLKKINKVKKNSRRISNTQEPKLVERLIKISRVSKVTKGGKKLSFRAIVVVGDENGKVGVGVAKADDVVNAFKKAKTDGRKNLIELPITKALSIPHNVAGNFGACKVIMRPSIEGSGVIAGGAVRIVLEVAGVKNVIAKQLGSNNLLNNARASVCALQNLTTKAQVAKKRNLD",
    "output": "With S4 and S12 plays an important role in translational accuracy."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPRYKTVEQVLSLMKDRTRVRNIGIIAHVDHGKTTTSDTLLAASGIISPKVAGEALALDYLNVEQQRGITVKAANISLYHEAEGKGYVINLIDTPGHVDFSGRVTRSLRVLDGSIVVVDAVEGIMTQTETVLRQSLEERVRPILFINKVDRLVKELKLSPQEMLNRLLDIIRQVNNLIDMYGEPEFKEKWMINPQAGNVIFGSAKDKWGFSLPMAQKKGINMKNVIDAYTASDKSKLEELAAQAPINEALLDAAIKFVPNPIEAQKYRIPKIWKGDLDNELAKAMLNADPNGPIVFMITDMKVDPHAGLVATGRVFSGTLRSGEELWLVNAKTSQRILQVSLYMGPTRELAEEIPAGNIAAVLGLDRARSGETAISVGFSNVQGSFERLHYISEPVVTIAVEPKNPKDLTKMIDALRKLSIEDPNLVVKINEETGEYLLSGMGFLHLEVSLQLLRENYGIDVVTTPPIVVYRESIRAKSQVFEGKSPNKHNKFYLSVEPLNDKTIELISNGTIREDMDSKEMAKILRDEASWDYDEAKRIIAIDENVNVFVDLTSGVQHLREVMDTVLQGFRLAMKEGPLAHEPIRGVKVILHDAVIHEDPAHRGPAQIYPAVRNSIFAGFLTSRPTLLEPIQKLDIRVPADLIGNVTAVITRKRGKILDVSQIANMSRITAEIPVSESYDMASELRGSTGGRAFWGTEFSRWAPVPDSILLDVVTKIRERKGLPKELPKVEDFLS",
    "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKLLNYAFVYRRFLLVVFTVLVLLPLPLIIRSKEAECAYILFVIATFWITEALPLSITALLPGLMFPMFGIMSSTHVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALRMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIVEAVAQQITSAEAEAEATQMTYFNESAAQGLEVDETIIGQETNERKEKTKPALGSSNDKGKVSSKMETEKNTVTGAKYRSKKDHMMCKLMCLCIAYSSTIGGLTTITGTSTNLIFSEHFNTRYPDCRCLNFGSWFLFSFPVAVILLLLSWIWLQWLFLGFNFKEMFKCGKTKTLKEKACAEVIKQEYEKLGPMRYQEIVTLVIFIVMALLWFSRDPGFVTGWSVLFSEYPGYVTDSTVALVAGILFFLIPAKKLTKMTSTGDIIAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCQVSGLSSWIGSKLSPLGSLPVWLIILISSLIVTSLTEVASNPATITILFPILSPLAEAIHVNPLHILLPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNILGVAVVMLGMFTWIEPMFNLHEYPSWAPDIVNQTMP",
    "output": "Sodium:sulfate symporter that mediates sulfate reabsorption in the kidney and small intestine . Can also mediate the transport of selenate and thiosulfate ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MELLCCEGDTVRRAQPDPALLLDDRVLHNLLTVEERYLPQCSYFKCVQKDIQPFMRRMVATWMLEVCEEQRCEEEVFPMAMNYLDRFLAVIPTRKCHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPLPKDKLLLIRKHAQTFIALCATDFNFAMYPPSMIATGSVGAAICGLQLDVGETSLSGDSLTEHLAKITSTDVDCLKACQEQIESVLVSSLRQTRQQTQQRNSSKSVDELDQASTPTDVQDINL",
    "output": "Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNYRIDFAVLSEHPQFCRFGLTLHNLSDQDLKAWSLHFTIDRYIQPDSISHSQIHQVGSFCSLTPEQDVINSNSHFYCEFSIKTAPFPFHYYTDGIKAAFVQINDVEPRVRHDVIVTPIALASPYRERSEIPATDAATLSLLPKPNHIERLDGEFALTAGSQISLQSSCAETAATWLKQELTHLYQWQPHDIGSADIVLRTNPTLDEGAYLLSVDRKPIRLEASSHIGFVHASATLLQLVRPDGDNLLVPHIVIKDAPRFKYRGMMLDCARHFHPLERVKRLINQLAHYKFNTFHWHLTDDEGWRIEIKSLPQLTDIGAWRGVDEVLEPQYSLLTEKHGGFYTQEEIREVIAYAAERGITVIPEIDIPGHSRAAIKALPEWLFDEDDQSQYRSIQYYNDNVLSPALPGTYRFLDCVLEEVAALFPSHFIHIGADEVPDGVWVNSPKCQALMAEEGYTDAKELQGHLLRYAEKKLKSLGKRMVGWEEAQHGDKVSKDTVIYSWLSEQAALNCARQGFDVILQPGQFTYLDIAQDYAPEEPGVDWAGVTPLERAYRYEPLVEVPEHDPLRKRILGIQCALWCELVNNQDRMDYMIYPRLTALAGSGLDTKIPA",
    "output": "Hydrolyzes aryl-N-acetyl-beta-D-glucosaminide (aryl-beta-GlcNAc), aryl-beta-GalNAc and chitin oligosaccharides. Can hydrolyze rapidly the artificial substrates p-nitrophenyl-N-acetyl-beta-D-glucosaminide (PNP-beta-GlcNAc) and 4-methylumbelliferyl-beta-GlcNAc, and is slightly active on p-nitrophenyl-beta-GalNAc. This enzyme is not processive, i.e. when it hydrolyzes (GlcNAc)n, both products, (Glc-NAc)n-1 and the terminal GlcNAc, are released before the enzyme attacks a second molecule of (GlcNAc)n or (GlcNAc)n-1."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MENNNRFMPHIRRTTHIMMFAHRNSFDFHFFNAR",
    "output": "A small protein (arrest peptide) encoded upstream of inducible ornithine carboxylase gene (speF) that controls expression of downstream genes (speF and potE) by transcriptional and translational attenuation. Its expression controls transcription and translation of downstream SpeF; translation pausing at low Arg levels on this mRNA prevents premature Rho-dependent transcription termination of speF and also enhances SprF translation by preventing sequestration of its ribosome-binding site. In the presence of high Arg levels translation of this protein allows the formation of an speF mRNA structure that is degraded by RNase G."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSTQLRAAEISDIIESRIEKFGIKAEERTEGTILNIKDGIVRVYGLRDVMFGEMVEFPENTYGLAFNLERDSVGAVVMGPYEHLEEGMTARCTGRILEVPVGEALLGRVVDGLGKPIDGKGPIDTSETSPIEKVAPGVITRKSVDTSLPTGLKSIDAMVPIGRGQRELIIGDRQTGKTAIAIDTIINQKHTGVKCIYVAIGQKQSSVAAVVRKLEEHGAMEHTIVVNASASEAAALQYLAPYAGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDIFYLHSRLLERAAHVNEAYVKEFTKGKVTGKTGSLTALPIIETQAGDVSAFIPTNVISITDGQIYLDVNLFNAGIRPAINAGLSVSRVGGAAQTKIIKKLIGGLRIALAQYRELEAFSQFASDLDEATRKQLEHGQRVMEILKQPQYQPLSVGEMAIIWYVVNNNYLDQVELKKVVDFERSLLSFLRDQHQDLLDEINKNPNYSEKIIEKIKAVVEEFVKTQSY",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MARRWSTKESQRRGSAWLLLFLAGVYGNGALAELSENVHISGVSTACGESPEQIRAPSGIITSPGWPSDYPAQVNCSWLIRANPGEIITISFQDFDIQGSRRCTLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSVSRKGFRLAYFSGKSEQPDCACDQFRCGNGKCIPEAWKCNSMDECGDSSDEEVCASDAHPPTTTAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDMPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPRKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPMTGRSSNIWNRIFNFARSRHSGSLALVSGDGDEVVPSQSSSRETERSRPHRSLFSVESDDTDTENERRDTAGASGGVAAPLPQKVPPTTAVEATVGSGGNSSAQSTRGGHADGREVSSVEAPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSTTQNRSPLRQLDTAVSGREDDDDVEMLIPVSDGASDIDANDCSRPLLDLASDQVQGFRQPHSAGNPGVRTSNRDGPCERCGIVHTAQIPDTCLEATVKTETSDDEALLLC",
    "output": "Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIAYIQGSITYKSPTQLIVDVGGIGYELQISLQTYDSLKDIAASCKIFTYLHITQDAHTLYGFSTIEEKQCFLQLLSVNGIGPRVAITILSALTPEALQQAIMTHDTITLQAVKGIGQKAAQRIILELQGKVGKVGNMLSLQPSGQEAIYQEALAALSKLGIHKSTAEKTVAAILKEHQGEITVESLIKLALKG",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "CYFQNCPRGXXXAMSDLELRQCLPCGPGGKGRCFGPSICCGDELGCFMGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGASFPRRA",
    "output": "Neurophysin 2 specifically binds vasopressin.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQATAALETDSDKNYPKNGGHFQNDKLYNPKKENMFFSNGCNGVILAFPDGKEDSLATEERASDKENSIVDQRDLSELSFSENQDSNRGNIFSQSSEFEDSNDYAFLNETYSIHYSESKLKDENLLHLYSGLHPEVHKRVEMIFDTLDNNSIGLGRSAEASGADCGDVQKSDVDEDSQQEYHSAELECISAHLAKTVSRSSLDVSELKTSSYDFKCGGNFEDNHGKLESGPSPSLESLNGFAQECSLQVSTSQSSDMLQEYHEPKYEKCKEQEVDLTYHKAFDGILQRSSSPLNHQKVPETQVYTKEVKSQTTESKDFYGNRIFQNKALQRPENATMFPQDRALETHLKANDAHQPSGPCALDDSVISLCGSSQYKSLPEPGFFSPVIPRVAVTDYQAEVEGSCLHHVQGSATNKACSLMKEVCLTSVPDAAACIAAVQQTLHVSSRVNASSSIVSASSITETKMVRQSQAEEWQSDKRSVACNTAWSCGQQCRDAQRAAPGSDSGRPLSTGCLKPSGNSLNENSLELRKVFDTTDRQKHCNRAFQLCEEKAVPSRCCQKTTERAIKAEMHLLDVCYQMCHRHCHHIYKLVMESRAGLNRNLQTDSAKKELGAALLSVLEDLKLRYMNLKGKVHKGIPLEELPPLSVESKLLSAFSDFVSRLMKDEACSLSGANSELDNQSLPDVDVSPGLLKTLSQMSFIPDSSQPEQGKSPMSDVCKNGDTDIGFNCLKLNDKECKTVQEASEDWFDATERLIGADFSETQDSTAECEEWQPRNPLELKNSELHGKGQGFLIHVGGLCPSVSEADLRSHFQKYQVSEISIYDSTNYRYASLAFAKNSNAKMAVKEMNGVKINGKSVTVRLVKIPGEYTPPPLSTTGNSTSMNHLEKNTNKDATSASSICRLPRAKSRQLESEQDSEFPPLDQGVKKNCNQMKSGQLLPETPFQFIPPNTLNLRSFTKIMKRLAELHPDISRDHIIEALQEVRINHKGFLNGLSINTIVKMASSFLRNSALK",
    "output": "Component of intercellular bridges during meiosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells. Not required for fertility."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGNSSATEDGGLLAGRGPESLGTGAGLGGAGAAALVGGVLLIGLVLAGNSLVCVSVASERTLQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVASPVVCGLNDVPGRDPAVCCLENRDYVVYSSVCSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPFFPDCPPPLPSLRTSPSDSSRPESELSQRPCSPGCLLADAALPQPPEPSSRRRRGAKITGRERKAMRVLPVVVGAFLVCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC",
    "output": "Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs. Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase (By similarity). Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNIAVVGLSHKTAPVEVREKLSIPEAKLEEVLAHLKSYPHIQEVAILSTCNRLEIYAVVTETEQGIIEISQFLSEKGHIPLHHLRRHLFILLHQDAVRHLMRVAAGLESLVLGEGQILAQVKNTHKLAQKYGGIGRLLDRLFKQAMTAGKRVRSETSIGTGAVSISSAAVELAQMKVIDICVCRVTIIGAGKMSRLLVQHLLSKGVSKIAIVNRSLRRAQELAGLFPEAQLQLHPLEEMINAVSVSDIVFTSTGATEPILNRSNLESIIAVNQSLMLVDISVPRNVDADVQQLEQIQSYNVDDLKAVVAANQESRRRLAQEAEGLLEEEVESFELWWRSLDTVPTISCLRDKVETIREQELEKALSRLGTEFAEKHQEVIEALTRGIVNKILHEPMVQLRAQQDIEARKRCLQSLQMLFDLDIEEQYT",
    "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "METKKTLREGYTTGLCAAAATKAALTALITGQVQTDATIRIPIGRVVTFSLASCSFDGETATASVVKDGGDDPDATHGALIVSTVSWASSPGVHIDGGEGVGRVTKPGLPVPVGEAAINPVPRQMIHEAVNEVLAQYGLHRGVNVVISVPGGEEIAKKTLNPRLGIMGGISILGTRGIVVPFSTAAYRASIVQALQVAKANGCRHVVITTGGRSEKYAMQEYPHLPEEAFIEMGDFVGFTLKQCKRLGIKMVSMVGMMGKFSKVAQGVMMVHSKSAPVDFGFLAALAEQAGASSALVAAVRGANTAAQVGDMMQEAGCMKFFELLCEACCQAALHEVGGGLTVATSIYTMNGQQLGKAVQTDGDDEVDRCGC",
    "output": "Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATLQFVLGSASFDHQQVMLDRLAAQYQQAPNDTYLYLVPNHVKFTTEVAVLKGLKKRLKQTGNYAQANVAVLSFSRLGWFLCKDDPDYQKPRLSNVGMAMVVAKIIRELKAESPDLLKMFRGESERQGFATEVTKQLVELQNANIQPADLAPDQETGIIKRALASQAGGGRASQSTVFTDKMTVLYEIYRRFEAAVTTHVTAPDRSAMLLNHLEAADLSTTHVYLDRFAGEFSAQEQLIVDALIQRAADTTVSLILDRDYRGRELPSQNNLYYRSAKQYQDLLNLATQQVGVDVLDPIVLNQPNQRRVSDALVGVEEWMEADARFALPDRLPAPTDQVGFFTAPTRVAELNRVATKIRQLVATGQYRYRDFLVVTRHLDGYQTMLEPIFSRHQIPVFNDNQRPMATSPLATFTAALFKVLKDYYQEADVMELLKTGLLVPETPEELQQEGRAKRNPNTFMTAVYRTENYCLKFGKGGRSWFDERPWRLEGEQPESDALKRQNAQINWVKNYIKDELAPALADLQTATTGRELATKFYQFLLDQGVRHQLYSWAHQAQESGQLTQLRDVQQIWQTFGTLLDEYVTILGDQVAPTEQPGQLVAEFADLMNAGFNAGRYAQIPSTLDQVLVSESGMIQDNQRKVLFIMGATDDVMPEVKASEGLLSDPDRELLKRGLNDDQFLPISGTDQINNEPFLNYLSMLSVTERLYMSAPLMSSDDSELTLSPYLKGLARHFNQWDDQNNAPTTDLPDRPNPRASEDDVWSFVAAPAVTMGNLIEVERLSKDTGRKLTSAWRDVARALTRYDEGLTGRLNDIRDGQYAKNEAVPLQPELAARLYTTNRQGQVTNQLTASISQLEKFYQNPYDYFLRYGLHLKKRDELEVSSDKSGTLNHDALAFFVQSVIDEPDLQLADLVKEEHQGRQAELIDQAFEQAMNQQEELRELAANNSRVNLQLQVAKQLITTMAKTLCLQATQTDAQPVAVEKAFGQADWTGESQAAELPALTFDLTGAGLGEGAKVSLRGRIDRLDELKLGEQTYQLVVDYKSYNKAFDLVDAYAGQALQMLAYLNALQAANPGKQLLGSLYLRLYVPTVDAGKEGTAEELKEHLYQGITINDDAVLAALDHGLGEKGATLLSIKKKSKKDTSRFKVSADDQFSAKAGSNLVSPTDLKRLMDHNAELIKEAAVQILQGQNEIRPYRRQVGTTAETGLAFSDFLDVSRFDQALDDYKEIELTDADVEAKFEQEEE",
    "output": "The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' -> 3' nuclease activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKIALDAMGGDYAPIETVKGALEAIKESNISVVLVGKEEEIKKILQDYHYNESKIEIVHAEEVIEMHEHPAFAVKEKEDSSIVKAIKLLKEKKVDGVVSAGNTGAVMSSALLYLGRIRGIKRPAISTLIPTLTQIPSIILDIGANVDCKKEYLEQFALMGKVYMEEIFNVKNPKIALLNIGEEEGKGNQLVQETYTLLKNNPLFNFIGNVEGKDLFKGTANVIVCDGFVGNVAIKTAEGVAETLFDLLSSEIKSSLWSIILGLLLKPKFKNVKKKLDYSEFGGAPLLGVDGTVIISHGRSKAKAIKNALKVAEKMVKLEVNKKILEGLNKITDRGD",
    "output": "Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKTGGNDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGVPTPKEIRRVLDDYVIGQDFAKKVLSVAVHNHYKRLAHATKHNDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLERIISQRGKGTSIGFGASVQAPDDRRTGEVFRSVEPEDLLKFGLIPEFVGRLPVLATLEDLDEEALKKILQEPKNALVKQYQRLFEMENVELTFQDEALGLVARKAIERKTGARGLRSILETILLDTMYDLPGLDSVEQVVIGPEVVDGKSKPLFIHGDRNKDAPASVSA",
    "output": "ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTEEVSRKQNFRQLGLSKWLVESLDAMRIRTPTAIQSGCIPEILKGRDCIGGAKTGSGKTIAFAGPMLTQWSEDPTGMFGIVLTPTRELAMQIAEQFTALGSYMNIRVALVVGGESIVDQALQLQRKPHFIIATPGRLAHHILNSGDDTVGGLKRVKYLVLDEADILLTETFSNDLKTCVGALPPKEKRQTLLFTATITDQVRALQDAPVQKGKQPLFCYEVENVDNVAIPSTLNTEYVLVPEHVKEAYLYQLLTCESYANSTAIIFVNRTTAAEVLRRTLKALDVRVASLHSQMPQQERTNSMHRFRANAARVLIATDVASRGLDIPTVELVINYDIPSDPDTFIHRSGRTARAGRKGDAISFITQRDVSRIEAIEARINMKMTECDKVHDTAVIRKALTKVSKAKREALMAMEKENFGERRKLQKRKTQKDGKRV",
    "output": "ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRTAEESSGTVLHRLIQEQLRYGNPTDPTLLAIQQQALRGGSSGGGAGSPRSSLESLTQEESLSPQLSARQEPQGQEHQGDFQHSESPVCHLYQLHTEELPTYEEAKAHSQYLAYQRGQIGLHQGSLESPGGVGGAEQDDSMWDAKREHARSLSERLLQLSLERNCAHDNIPMSSSHSYPQLSNNHSDTVVNEQSVHQPDQRGPPPEYPFMVRSPGYMLSHSQEHGHYYNEPPPAFHSQHYRLFPTQPQAPRHNGLPTLTPAGQDVNVGGYSIPANNFQMEQLIKENERLKREVDSYSEKAARLQKLEQEIQRISEAYETLMKGSAKREALEKTMRNKLESEIKRLHDFNRDLRDRLETANKQRAAIEVEDKSRHAFAKLVEQNEDHLRERERLEKETQHLRASGEEWKRRREALEQALITAQTRNRQLEEELRRKRAYVEKVERMQSALAQLQAACEKREALELRLRTRLEQELKSLRAQQWQAQTQHASPGSYLDLNVSSLQQQLREREEQVLALEADITRWEQKYLEESTMRQFAMDAAATAAAQRDTTIINHSPRNSPNSSFNEDLPSPNHRHQEMENRIRALYAQLLEKDAIIKVMQQRSRREQGRPELQGLRPARSVPSINTVATASTTRAKGKSLSDDQTAVASLPPLPHLLAKIQCRDSSTQCDSEEPSCKAEPADVAVSAPEPSTASSSESTSLKTTQISSAVENDMVEILI",
    "output": "Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments and for cell movements during embryogenesis. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSVTVEVADEETHDVPLVEQVRTTPDQNVDVKVQENNVVTTKIGPKLETIPAAKMQDDNGDEEKAENSEGAAAEKVEKQHDDDGVVVHEETDGVASSRSSHHDKQKPGETKKSGDGKMDDDDIITTARSSSRRICGSAASSSDSETADDAPLLPDEGPSHAVRLEMPGDKPASPHDRFPKTPLKTLVAFLMLVVAAAGNTITLSWIHERYPLTPPLPDIVFELIPKIPWGLRLCENLMIGSFVSLLVLILFHRHRWIVLRRLCFIGSILYGMRCITMMVTPVPKADEDFECSPRFGENATFSLIVMRGVWSMFGLGLNLFDNQKVVLCGDYIYSGHTLVLVVSALFIGEYSPRRFYILHWLSWLVCSVGVIFLVLSHGHYTIDVILSYFACTRVFWAYHTQAAHPSIRLSVQNHQAKEFWFPLLRWFEGDIRRPVPRRFDCPISYSQVCNAFRRVRPRGRNGAARPAFE",
    "output": "Sphingomyelin synthases (SM synthase or SMS) synthesize the sphingolipid sphingomyelin (SM) through transfer of the phosphatidyl head group of 1,2-diacyl-sn-glycero-3-phosphocholine (phosphatidylcholine, PC) on to the primary hydroxyl of ceramide (N-acylsphingoid base), yielding 1,2-diacyl-sn-glycerol (diacylglycerol, DAG) as a side product. Functions as a bidirectional lipid cholinephosphotransferases capable of converting PC and ceramide to SM and DAG and vice versa depending on the respective levels of ceramide and DAG as phosphocholine acceptors, respectively."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH",
    "output": "ATP-dependent specificity component of the ClpAP protease. It directs the protease to specific substrates. It has unfoldase activity. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "VLSPADKTNIKSTWDKIGGHAGDYGGEALDRTFQSFPTTKTYFPHFDLSPGSAQVKAHGKKVADALTTAVAHLDDLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLACHHPTEFTPAVHASLDKFFTAVSTVLTSKYR",
    "output": "Involved in oxygen transport from the lung to the various peripheral tissues.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDDHLYRRRAAERALDYVESGMAIGLGTGSTASFMLRGLAARLADGRLQRVVGVPTSEQTAVLARELGIPLTTLDRHPSLDLALDGADEIDPHLRLIKGLGGAMLREKIVAASAARFVVMASVSKRVERLGERSPLPVEVVTFGMPLCIRRLAALGGEPVLRCDHSGAPFVTDEGNLILDCHFGVIADPEALAAAICAIPGVVAHGLFLGMASLAVIAGPDGIVELECPDASRR",
    "output": "Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSEATTTLDGWYCLHDLRSIDWAAWKTLSSDERGQAVSEFLNVVEKWNDVAAAKKGSHAMYTVVGQKADIMLMILRPTMEELNEIETELNKTTLAEYMVPAYSYVSVVELSNYLPADEDPYQNPQILARLYPELPKANHICFYPMDKRRQGDDNWYMLPMEERKKMMYSHSKIGRQYAGKVRQVISGSVGFDDFEWGVTLFADDVLQFKKLIYEMRFDEVSARYGEFGTFFVGNILPDEKVEKFLHI",
    "output": "Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "PLAKKHNVKILPADSEHSAIFQCIQGLPEGALRRIILTASGGAFRDLPVEKLKEVKVADALKHPNWNMGKKITVDSATLFNKGLEVIEAHYLFGAEYDDIEIVIHPQSIIHSMVETQDSSVLAQLGWPDMRLPILYTLSWPERVYCSEITWPRLDLCNVDLTFKKPDHVKYPSMDLAYAAGRAGGTMTGVLSAANEKAVEMFIDEKISYLD",
    "output": "Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). Required for chloroplast development."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTQYTPMIQQYLKVKADYQDAFLFFRLGDFYEMFFEDAVKAAHELEITLTSRDGGSSERIPMCGVPYHAAKNYIEQLVEKGYKVAVCEQVEDPKTAKGVVRREVVQLITPGTMMEGRTIDEKENNFLAALTHFEDGSYALACNDLTTGQNTVTLLTGSVEDILLEVYATGSKEIVVDSSFSKDELNKLTETLKMTISYEDATAIPEGLEHLVKNVSQAKLIKAVGRLFNYVIRTQKRSLDHLQPVEIYYTNQFMKIDVHSKRNLELTETLRTKEKTGSLLWLLDKTKTAMGGRMLKQWMERPLIQKERIEERLEMVETFVNDYFLREDLKEKLKEVYDLERLAGKVAFGNVNARDLLQLRRSLLQVPAILEAISLLDNAYAARLIQGADPCESLTELLGRSIQENPPLSIKDGDIIKDGYNDKLDQYRYVSKNGKTWIAELEKRERDITGIKSLKIGYNRIFGYYIEVTKANLGALPEGRYERKQTLANAERFITDELKEKETLILEAEEKIVQLEYDLFTALREEVKVFIPKLQHLAKVISELDVLQSFATVSEEEQFVKPVLTTKREIFIKDGRHPVVEKVLNGKLYVPNDCIMPENMDVFLITGPNMSGKSTYMRQLALVTVMSQIGCFVPATEAVLPVFDQIFTRIGAADDLISGQSTFMVEMLEAKNAIANASERSLILFDEIGRGTSTYDGMALAQAIIEHIHDQIGAKTLFSTHYHELTVLEDSLDQLKNVHVSAIEENGKVVFLHKIQDGAADKSYGIHVAQLAELPDSLIARAKEVLAQLEGQEEIVIPKRVEVKAQEQEVIPEPIVVKEEPIEIEETKVDNEEESQLSFFGAEQSSKKQDKPALDAKETAVLTQIKKIDLLDMTPLEAMNELYRLQKKLKKG",
    "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKGTQRLSRLFAAMAIAGFASYSMAADTIKIALAGPVTGPVAQYGDMQRAGALMAIEQINKAGGVNGAQLEGVIYDDACDPKQAVAVANKVVNDGVKFVVGHVCSSSTQPATDIYEDEGVLMITPSATAPEITSRGYKLIFRTIGLDNMQGPVAGKFIAERYKDKTIAVLHDKQQYGEGIATEVKKTVEDAGIKVAVFEGLNAGDKDFNALISKLKKAGVQFVYFGGYHPEMGLLLRQAKQAGLDARFMGPEGVGNSEITAIAGDASEGMLATLPRAFEQDPKNKALIDAFKAKNQDPSGIFVLPAYSAVTVIAKGIEKAGEADPEKVAEALRANTFETPTGNLGFDEKGDLKNFDFTVYEWHKDATRTEVK",
    "output": "Component of the high-affinity leucine, isoleucine, valine transport system I (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids . Binds L-leucine, L-isoleucine, L-valine, L-threonine and L-alanine with nanomolar affinities. Can also bind L-homoserine with high affinity ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKVATRFAPSPTGALHIGGVRTALFNWLYSKNKNGTFHLRIEDTDKERSKDEHKIQIIKSLKWIGIDHDGDEYIQSTKINDHVNVANELLKNGHAYKCYCSSAEIEEQKKRARQKKLPYVYNRKCRDLQETNAPTIIKPVIRFKIKIEGTSVLKDLVQGDVEIENTTIEDFIILRNDGTPTYNLSATVDDHQMKMTHIIRGDDHKINTFKQMQIYLAMSWDLPNFAHIPLIHTIEGKKLSKRDNASTLDDYSKIGIMPDALRNYLLRLGWSYQDKEIFTLKESIELFNLEGIGKSPSKLDMSRILSLNEHYIKTINENELYDHLVKYCEIYKEKIKPEKETKIKPSLIFLKNKAKTLEDIFNNAKYIIFDDVKFEDKDLELIDDKAKSIIKEFKEKLISINTLNKETLEPIVNDLIKKYETNFKGVGQPLRIALTGSKFGPGLYDIIISLGNEEVERRLGNKIII",
    "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MANLTTLAVSTRAKAGKGAARATRREGLVPAVIYGGKQEPSIIALDPRVIMKELHRGGWSSRVYNLAAEGAEPVAALIRDVQLHPVTDAPIHVDFQRVAAGTKVHVEVSIAFVGEEKSPGIKRGGVLNVVRHYVDVQADPANIPEHFTAELSGLDIHDNVRWTDLKGTEGVVLGSGQAADMVIASIAAPTIDAEMEAEAAAKAAAEAEAAAKPGAKKK",
    "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGFRKGHLPRPIFDQKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQDWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAAENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVTFPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKELAAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDMYFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYNMEVAQVQNLLSADMLKHDITIKKAVELITSTATVK",
    "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSDKEDEKQSQPVLKDDKQDQTEEPAIDDNVNGDEGPSDEEEGDDVFDSSEEDEDLDNDEEEAQKVREGFIVDDDEEGGEEDEVVKKKSRRKRRAREEENEALDEDDLDLLMENAGFKRPSASEAAKQRSGKLKRLKRVGDDEEESASAEPESEVARTNKLDDFFSEEEEEEELEDDGTGRAPSRKGVEKTVTLADDMDDFIEEDEFSDEDEEARKFRIAEKKRIKEQRLAQPTQITGLSPDKVDEMFEVFGDGHDYDWALELENEEELDRLEESSENEQDENELGIDSKRKKKLTLQDIYDLQDLKKNLLTEEDMNIRKADIPERYQELRTGLKNYGKLSPEDLELEKNWISDKIAVDKNFDADYDTTEFKEAIGNAINFIQQENLEVSFIYAYRRNYISSRSKDGFVLIEDDLWDIVFYDTEFHSIIYKRDYVKTFYEKLDIHDPIVDEYFSNQSMTELNSLQDIYDYVEFKYAQEINDVLLSTQQDATSKKHLKNSSYEKFKASALYQAINDTGITAEQVGENISAEHQLHPVVDHPSLKPTDSVANILEGPEAKDLQIFSQNPKLALETIEKYYALELSKNPKVRQKIRDDFYKYYIVDVALTSKGRKEIQRGSPYEDIKYALGRTPAHFRSEPDVFLRMLEAESLHLMNIQIHVSSQDQYTNHLFQTSLETSNTSEIASEWNSFRRDAFDSALNKVFSDVSQEIKDELKKTCLRLVTKSVRHQFMFKLDQAPFIPNPKDPKIPRVLTITCGQGKFGSDAIIAVYLNRKTEFVRDYKIVENPFDRKEPELFENALDDIIQHCQPNVIGINGPNPSTQRLYKKIQEIVQKKQIVDNRGSHVPVIYVEDEVAVRYQSSERAAQEFPSKPTLVKYCIALGRYIHSPLLEYANLTNEELLSLSIHSHQSLLTRELFLQALETSFVDIVNLVGIEVNKATDNHYYAKALRYIAGFGRRKSADFLESLQRLNEPLLARQQLITHDILTKTIFMNSAAFLYISWNEKNQRYEDLEHDQLDGTRIHPEDYHLATKVAADALEFDPDAIAEKEEQGTMSEFIELLREDPDRRTKLESLNLEAYAEELEKNTGQRKLNNLNTIVLELLEGFEELRNDFHPLHGDEVFKSLTGESEKTFFKGCIIPVRVERFRHNDIYGVTNSGVECVINAQRHIGAQLKRPAEEVYEIGKTYPAKVIYIDYDNISCEVSLLEHDIRRQYVPIHYSKDPSIWNVEQEMKDQEIEKKLALEEARAKRTHRVINHPYYGNFTGPQAEDYLRSRERGDFVIRQSSRGDDHLAITWKLDKDLFQHVDILEKDKENPLALGKTLIVEDQKYHDLDQIIVEYLQNKVRLLNEITSNEKFKKGTKKEVIKFIEDYSKVNPNRSVYYFSFNYEHPGWFYLMFKINAQSQLYVWNVKLTHTGFFLVNYNYPTVIQLCNGFKTLLKSSSRNKTQDNNNNNSGGYYGY",
    "output": "Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDTLGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTAKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTKNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR",
    "output": "ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (By similarity). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (By similarity). Seems to contact the pointed end of the daughter actin filament (By similarity). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLDPNLLRNEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVNTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDTLLAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEIRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNHDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEVPLTNLVRDEIIDEDQLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG",
    "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPQNDYIERHIKQHGKRLDHEERKRKREARESHKISERAQKLTGWKGKQFAKKRYAEKVSMRKKIKAHEQSKVKGSSKPLDTDGDALPTYLLDREQNNTAKAISSSIKQKRLEKADKFSVPLPKVRGISEEEMFKVIKTGKSRSKSWKRMITKHTFVGEGFTRRPVKMERIIRPSALRQKKANVTHPELGVTVFLPILAVKKNPQSPMYTQLGVLTKGTIIEVNVSELGMVTAGGKVVWGKYAQVTNEPDRDGCVNAVLLV",
    "output": "Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles. Under normal, rapid growth conditions, high levels of NSA2 would allow the progression of pre-60S particles through the ITS2 processing."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGNMGIWQLLIIAVIVILLFGTKKLRSLGGDLGGAVKGFKNAMSSEEEKKALEETASEKATPSVEKTAPNAEKKTETKDKEQV",
    "output": "Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "AEKIKICLQKQVNSSFSLHNGFGGNLYATEEKRMFELVKPKAGASVLNQSTWIGFGDSRTDKSNSAFPRSADVSEKTADKFRSLSGGSLMLSMFGPPGKVDYLYQGCGKHKVFYEGVNWSPHAAINCYRKNWTDIKLNFQKNIYELASQSHCMSLVNALDKTIPLQVTAGVAKNCNNSFLKNPALYTQEVNPSKEICGKENLAFFTLPTQFGTYECKLHLVASCYFIYDSKEVYNKRGCDNYFQVIYDSSGKVVGGLDNRVSPYTGNTGDTPTMQCDMLQLKPGRYSVRSSPRFLLMPERSYCFDMKEKGLVTAVQSVWGKGRESDHAVDQAYLSTPGCMLIQKQKPYIGEADDHHGDQEMRELLSGLDYEARCISQSGWVNETSPFTEEYLLPPKFGRCPLAAKEESIPKIPDGLLIPTSGTDTIVTKPKSRIFGIDDLIIGLLFVAIVEAGIGGYLLGSRKESGGGVTKESAEKGFEKIGNDIQILRSSTNIAIEKLNDRITHDEQAIRDLTLEIENARSEALLGELGIIRALLVGNISIGLQESLWELASEITNRAGDLAVEVSPGCWIIDNNICDQSCQNFIFKFNETAPVPTIPPLDTKIDLQSDPFYWGSSLGLAITTPISLAALVISGIAICRTK",
    "output": "Binds to the N-acetyl-9-O-acetylneuraminic acid residues on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HEF2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore. Displays a receptor-destroying activity which is a neuraminidate-O-acetyl esterase. This activity cleaves off any receptor on the cell surface, which would otherwise prevent virions release. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MADAASQVLLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGCPPYSPIYTSWIDCWCMLQKEGNMSRGNSLFFRKVPFGKTYCCDLKMLI",
    "output": "Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane. Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins. Does not mediate insertion of beta-barrel transmembrane proteins (By similarity). Also acts as a receptor for the truncated form of pro-apoptotic BH3-interacting domain death agonist (p15 BID) and has therefore a critical function in apoptosis. Regulates the quiescence/cycling of hematopoietic stem cells (HSCs). Acts as a regulator of mitochondrial fusion, essential for the naive-to-primed interconversion of embryonic stem cells (ESCs). Acts as a regulator of lipid homeostasis and has a regulatory role in adipocyte differentiation and biology (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHSIAIFGGTFDPVHNGHIKTSLAIQANFGFDSYYFLPCKSPAIKPPSFASSEQRVEMLKLALKPYPDFKIDTRELDRDTPSYMVYTLQSFRQEYTDSSLTLIIGYDGLLNLPQWYQWEKIISLANLLVINREEFFQKPVPKSVQTLLNQYRNDDKNILLNHHAGSICLYNAGHYDISSTKIREQLKQHKDVKNNLPDLVYDYIKKQELYQ",
    "output": "Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLTLGELAKKLDAELIGEASHVVDGLGTIQSAGPSQLTFLANPRYRSFLEQTNAGAVLIPESQREFCPVPALIVKDPYLSFAKASAFFEVAPQVQPGVHPAAVVDATAQIHTSASIGPNAVVEAGVIVGEGAVIMANSVVGAGCHIGDQCRIWPNVTIYHGVTLGPRTTIHANCVIGGDGFGFAFNGAGWTKLHQVGGVTIGADVEIGAGTTVDRGAIEDTIIGDGVILDNQIQVAHNVVIGDHTAIAGKAGIAGSAKIGSFCLIGGAAGIAGHIEVCDKVQILAMSLVSSSIKEPGTYGSALPVDSQSRYRRNVARFRNLDDLARRVRKLERLSD",
    "output": "Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSPDQTAVEYTAKDIEVLDDLEAVRKRPGMYIGGVGVRGLHHLLWEVVDNAVDEALAGYCDTIKVSLHKDGSASVEDNGRGIPTEMHELGKSALEIVMTKLHAGGKFSKKVYRVSGGLHGVGVSVVNALSEWLEVWVKRNGKIYYQKYQRGSRSPEAGHRTEVLGETKEHGTTVRFKPDREIFETTEFKYEIVAQRLKELAYLNRGLKIILFDEREGKEETFHFEDGIIGLVRSLNRNRKPLHEPIYIETTKDGVSVEVAIQFTDSDVENIQAFANNINTSEGGSHVVGFRAGLTRAVNEYGKKHLKKFEPVTGVDIREGLTAVISVKVPEPQFEGQTKTKLTNSDVKTVVESAVYSGVLRWLEENPAQAETLLNKFILNKKAREAAKRAKELVKRKNELITTLPGKLADCSSKNPEERELFIVEGESAGGSAKQARDRRFQAILPIKGKIINVEKAGMARVLKNDEIKAIISAIGAGIGKDFDITKARYRRIIIMTDADVDGAHIRTLLLTFFYRYMRPLIESGYLYIAQPPLYQIKKGKKSYYAYSDEELKRTLEQVGGGEVQRYKGLGEMNPQQLWETTMNPENRILIQVTLEDAKRADELFSILMGEDVESRRNFIMAHSKEVKNLDI",
    "output": "A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSNTTRSSRVTIGRIGTTPQITDPWSSGLEKQRPSRCGGPKSLAEPTYRKIGRRKMMLHMRVHDPGTTVTQRAKETATAKLNRIYLCTFNRMAQSCIYFVLFLVILSPNTSCALRSSAGETQNYVGILSNDSATTTYDVSSLHSSRRTNPPSSSSSSSSNVDVDYRNDRELHKVDLVGLGGERAGQAETISGGKYDYNYENTHTNASAKDEIVERQSNSLDFDGVDMFGAFSIPEEAIYTNEFAVNIPAGKQMADVIATKHGFINRGQIGSLDNYYLFQHHHVSKRSLRSSRKHQGALKSENEVKWMQQQHEKVRRKRDGPYQDLPTYSPYNLLRQHGGYVVDPNPHLSFSPESISLASHSQRMEYRDVSSHFIFPDPLFKEQWYLNGGAKDGLDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGNDSDPTPQDNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLDGKVNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSRPAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGCAGTINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSNFDDWPFLSVHFWGEKAEGRWTLQVINGGRRRVNQPGILSKWQLIFYGTSTQPMRLKSELLNSSPQLRSPSSSNPFLFPSASNIGQPANEGGNFNTDSFASYLNYQNIFSSAGSDPEPATATLDGQNVTAAIAGGSSAESLGFTASAAQLVAAPETRDGDKKILHSCDAECDSSGCYGRGPTQCVACSHYRLDNTCVSRCPPRSFPNQVGICWPCHDTCETCAGAGPDSCLTCAPAHLHVIDLAVCLQFCPDGYFENSRNRTCVPCEPNCASCQDHPEYCTSCDHHLVMHEHKCYSACPLDTYETEDNKCAFCHSTCATCNGPTDQDCITCRSSRYAWQNKCLISCPDGFYADKKRLECMPCQEGCKTCTSNGVCSECLQNWTLNKRDKCIVSGSEGCSESEFYSQVEGQCRPCHASCGSCNGPADTSCTSCPPNRLLEQSRCVSGCREGFFVEAGSLCSPCLHTCSQCVSRTNCSNCSKGLELQNGECRTTCADGYYSDRGICAKCYLSCHTCSGPRRNQCVQCPAGWQLAAGECHPECPEGFYKSDFGCQKCHHYCKTCNDAGPLACTSCPPHSMLDGGLCMECLSSQYYDTTSATCKTCHDSCRSCFGPGQFSCKGCVPPLHLDQLNSQCVSCCQNQTLAEKTSSAACCNCDGETGECKATSTGGKRRTVVGSGSAYKSSESKHGSFENDGNAREFVLRLDSPLTAITAIAVAICLLIITIFSIIFAVLQRNSNHVSRNSVRYRKIANTSSGRRKNLSAKPTSDARFIFNIGEDDDTDGDNSDDELDGNVGTDINNRIVYDRKGNDHGHEFYIESTNDIDAIEFHCNGAGAQKAETQLQRCNANGDDDDILHYDRHTNAERKNHPSSTTSRTNIRS",
    "output": "Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKKLLKISAISAALLSAPMMANADVLASVKPLGFIVSSIADGVTGTQVLVPAGASPHDYNLKLSDIQKVKSADLVVWIGEDIDSFLDKPISQIERKKVITIADLADVKPLLSKAHHEHFHEDGDHDHDHKHEHKHDHKHDHDHDHDHKHEHKHDHEHHDHDHHEGLTTNWHVWYSPAISKIVAQKVADKLTAQFPDKKALIAQNLSDFNRTLAEQSEKITAQLANVKDKGFYVFHDAYGYFNDAYGLKQTGYFTINPLVAPGAKTLAHIKEEIDEHKVNCLFAEPQFTPKVIESLAKNTKVNVGQLDPIGDKVTLGKNSYATFLQSTADSYMECLAK",
    "output": "Involved in the high-affinity zinc uptake transport system."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSDIKEFNLIDVRNNSSIVNDLNNVYKLWGYEEISPSFINNLETIKGREVIDGDELIGIVSNSSLCLRPEMTTSIVKLTSTRLLNKKRPIRLFNSGIVFNKKQSYKNTYKFQENLQSGIELISYDTQYPEIEVINILFDAIDNINLIDSCNLTLLVSTTKIMDLILFNYKNNNYEEIKKCMVNLDHESLDKLNIDNNDKAILKELLFTRGEPAIILKKLKNIYGNNNVIEELDCLFNTLSKISKKYNIKIQLDPTYQPHLNLYAGIVFQLICDNKNVKTIIAKGGRYDELVRYFNPNEKIINGIGFTISIDNLRELIVEKSQTKKKVLLLFKNSYLLDKGINEQKALQKKGIITILYLNPCNDNSKANILMKEHNCTEIQWIK",
    "output": "Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKNGAICHPVFCPRRYKQIGTCGLPGTKCCKKP",
    "output": "Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria, with highest activity against Gram-negative bacteria (By similarity). Antimicrobial activity against P.aruginosa seems to be salt-sensitive and is reduced with high salt concentrations greater than 25 mM (By similarity). Also exhibits antimicrobial activity against the yeast C.albicans (By similarity). Permeabilizes C.albicans cell membranes via targeting plasma membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2), thereby leading to cell fragmentation and cell death (By similarity). Acts as a ligand for C-C chemokine receptor CCR6 (By similarity). Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells, such as immature dendritic cells and memory T cells (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAEFPAELYYSKNHEWMRKESDETFTVGITDHAQEQLGDLVFVELPETNIHVDAGDEVAVVESVKTAADVYSPLSGKVIEINNALENEPATVNRDPYGDGWLYRITIDDEKELNDLLDADGYQTLIEAES",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRTLWITAVLLVGVEGHLLQFRKMIKKMTGKEPIVSYAFYGCYCGKGGRGKPKDATDRCCFVHDCCYGKVTGCDPKWDYYTYSSENGDIVCEGDNPCTKEVCECDKAAAICFRDNLKTYKKRYMTFPDIFCTDPTEKC",
    "output": "PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MARFFRRRKFCRFTAEDVKEIDYKDLNTLKAYVSETGKIVPSRITGTKARYQRQLATAIKRARFLALLAYTDSHGR",
    "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSQIHKHTIPANIADRCLINPQQYEAMYQQSINAPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDASQSKHISYKELHRDVCRFANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVVVLKRTGGKIDWQEGRDLWWHDLVEQASAQHQAEEMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMAQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGNEKCPVVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVDNEGNPLEGATEGSLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHNIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTSNLGDTSTLADPGVVEKLLEEKQAIAMPS",
    "output": "Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTSHSAVRIAIFAVIALHSIFECLSKPQILQRTDKSTDSEWDPQTCPETCIPSKNITCSDGCVCVKLGEEEEGTCFNMTGVDWLGSPSDD",
    "output": "Salivary chemokine-binding protein which binds to host chemokines CXCL1, CXCL2, CXCL3, CXCL4, CXCL5, CXCL6, CXCL7, CXCL10 and CXCL11."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY",
    "output": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSVMPDHWIKERALKDGMISPFVDHKEGTGVLSYGLSSYGYDARLDNKFKIFANTHSVVVDPKNFSQDSFVDREGDFCIIPPNSFMLAKTVEYFNIPRDVMVVCVGKSTYARCGIVVNVTPLEPGWSGYVTLEFSNTSPLPVKVYAFEGACQFLFFSGKERCSKSYDEAGGKYMGQSDVTLPIIS",
    "output": "Catalyzes the deamination of dCTP to dUTP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MALRGPAGLGPGSRRPLDEAVAGAEGREAPALVAAGGAPEDDEEDDGRGRGLLRWDSFSAWLHCVCVVGFDLELGQAVEVIYPQHSKLTDREKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDQFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLHLPIMGVVMKVRIPTCHDKPGTTQIVQLTQQVDTNISVILPTVHEVDIFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPTGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEEIIKQLQKGVQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSRIKGDWIGLYRHFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWIQKHTEVETVDLVLKLKNKLLQADREHLPVKPDTMEKLRTHIDAIILALPEDLQGILLKTGMT",
    "output": "Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPEMEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQGGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVANPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALELKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEEAQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMTPVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQTMEKAVDVILGIVQKA",
    "output": "Cleaves the N-terminal amino acid of tripeptides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSTNDNWYIEHFQPTGSAIGFRISGKLDEVQSLFQKIEIYQTTDWGKLMLIDGAVMLTSRDNFFYHEMISHPALFTHPTPKRVVIIGGGDCGTLREVLKHPGVESATQCDIDEQVTRMSEKYFPELCDSNHDARAELLFDDGVAYMANCPAGSVDIVIVDSTDPVGPAEGLFNKAFYESCFKALKDDGLLVQQSESPLALLDLIKEMRTEMGKAGFQSFKTLPFPQPCYPTGWWSVTMASKQAKADFAFRQGAAQAKGFETLYYTAHLHTGVLVAPPFVAKALGE",
    "output": "Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLGLVGRKVGMTRIFAEDGASIPVTVLDVSNNRVTQVKTPEIDGYAAIQVAFGKRRASRVSKPLAGHLAKAGVEAGHVLKEFQIEADQLASFKAGDQVAVTIFAEGQKVDVTGTSIGKGFQGGIKRHNFSSNRASHGNSLSHNAPGSIGMAQDPGRVFPGKRMAGHLGDVQSTMQGLTIVRVDADRQLLLVKGAVPGAKGSDVVVRPAVKA",
    "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSSARPVRAARGTTLTARSWSTEAPLRMLQNNLDPEVAERPDDLVVYGGTGKAARNWASFDAIVRELTTLSDDETLLVQSGKPVGVLRTHEWAPRVLLANSNLVGDWANWPEFRRLDALGLMMYGQMTAGSWIYIGTQGILQGTYETFAAVAERRFGGTLAGTLTITAGLGGMGGAQPLAVTMNEGVALVVECDPERAHRRVKHGYLDEVADGLDQAIEKAEAAKAQRRAYSVAVIGNAAEVLPELLRRGVRADIVTDQTSAHDPLSYLPLGVELEDWEDYASKKPEEFTDRARDSMAKHVEAMVGFMDAGAEVFDYGNSLRGEAQLAGYGRAFDYPGFVPAYIRPLFCEGKGPFRWAALSGDPADIAATDRAILDLFGDDDHLARWIRLAGEKVSFQGLPARICWLGYGERHLAGLRFNEMVASGELKAPLVLGRDHLDCGSVASPYRETEGMADGSDAIADWPLLNALVNTASGATWVSLHHGGGVGMGRSLHAGQVTVADGTALAAQKLERVLTNDPGMGVIRHVDAGYDRAREVATERGVRVPGLA",
    "output": "Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRNKLNFQNIEHSYAFKELSKLPSIVSSKQLRTNSIFEAVKPELKNVQNDIQMFYSVIEREINSEISQIDLVETELKKSLKNVNKSYAKIMKRRTILSSNGKNKNLAIVDDFNKEVDGLESLITGLKETVHDMIDDLVTADSQLKSNNKSVTKEEINSQHYPLLFEILQKDYNHIFKESNNLSVQDADRKSIELDIEDRTEVKSSDDKDSMNKNINIMPIEDNSITHLSFEGEPIYTKVSHENSNQVTDKGINQLDENTLNQEIKNDNLICQRSLPPKNLSNENVVNDNYADSNCLKEEKKNEVDTSKSKMGTINSTPSSTTMGNGFILPNLTKVVKPTISTTFETVVNREF",
    "output": "Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKARVLLKPSSLTTCLTRAKAFFSSVSQSRSISHQMEMGPSDSERYCYDPVLRWNPEVEDYFTKAYGPDHFARISKALTRPSSYSCIRVNTVKTTSDAVIEKLTKILNDSEEGLKLVQPDGSSPVTKCQIPGLDYVVFVNGSGPHKIEYDSGLENPPKEVLVSRKCAEAVLRGAQVYVPGVLACTAHVEKGDAVAVCVAMEQPGDEGDWSVNMTRGTTLQGLPTDPYYRERSGLYIGMGTAMLSRAGMFRVPNGIAVDLNHRVFRLPSLHNILEGEIFLQNLPSIIVAHALDPQKGERILDMCAAPGGKTTAIAILMNDEGEIVAADRSHNKVLVVQNLSAEMGFTCITTCKLDALKSVCLPTTLNESTILINGDNSSSMTSHSELSSNEEMTSVTSRRSEADKSCEKNDSTEQPNGGDNVSQAYIRKNKGRLKNGRGRTQCQGGRAGKSQGFPPNSFDRVLLDAPCSALGLRPRLFAGLETVVSLRNHGWYQRKMLDQAVQLVRVGGILVYSTCTINPSENEAVVRYALDKYRFLSLAPQHPRIGGPGLVGRCEFPDGYIEEWLKPGEEELVQKFDPSSELDTIGFFIAKFSVGPKD",
    "output": "Involved in ribosomal large subunit assembly (By similarity). S-adenosyl-L-methionine-dependent methyltransferase that may methylates the C(5) position of cytosine in rRNA (By similarity). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (By similarity). Seems involved in the regulation of cell proliferation (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MALRVTRNTKLNTENKAKVSMAGAKAVPVTLAAASKPGLRPRTALGDIGNKVSEQAQARLPLKKELKTSVTGKVSAKIPPPKPLEKVPPVSEPEVELAETHEPEPVMDEKLSPEPILVDNPSPSPMETSGCAPAEEYLCQAFSDVILAVSDVDADDGADPNLCSEYVKDIYAYLRQLEEEQSVRPKYLLGREVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQDNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRTSKIGEVDVEQHTLAKYLMELTLLDYDMVDFAPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNHGLTKHMTIKNKYATSKHAKISTLAQLNCTLVQNLSKAVAKA",
    "output": "Essential for the control of the cell cycle at the G2/M (mitosis) transition."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKSIVFVALLGLALLAVVCSASEDAHKELLKEVVRAMVVDKTDAVQAEERECRWYLGGCSQDGDCCKHLQCHSNYEWCVWDGTFSK",
    "output": "Ion channel inhibitor."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKKYDFLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKVKTIEVEGKKVKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSYENIQNWMKSIKENASAGVSRMLLGNKCDIEAKRKVSKETGEKLAKEHGIRFFETSAKSSINVEESFTSLARDILLKSNKKPGPSGREVKLTSTEKKSSSKCLLL",
    "output": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in endocytic recycling and may regulate the transport to the plasma membrane of transmembrane proteins. May regulate the assembly and the activity of tight junctions. May play a role in angiogenesis through regulation of endothelial cells chemotaxis. May be involved in neurite outgrowth. Has also been proposed to play a role in post-Golgi membrane trafficking from the TGN to the recycling endosome. Finally, it has been involved in insulin-induced transport to the plasma membrane of glucose transporters."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKQKKQSPGTIALNKKALHDYFIEQKFEAGLVLAGWEVKSLRAGKAQLVDSYVLLKDGEAWLMGAHITPLTSASTHVIADPTRTRKLLLNKRELGKLFGAVQQKGYACVALSLYWKKHMIKCEIALAKGKKEFDKRHTEKERDSDREIQRAMRTKGKDD",
    "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSLLVVAPEWLTSAAAELQSIESALSAANAAAAVPTTGLAAAAADEVSTAVATLFAGFGQEYQAISTQLSAFQQQFALTLNSSAGSYSAAEAQSVSILDTLGQDVFGAINAPTEALLGRPLIGNGANGTATSPNGGAGGLLFGNGGIGYSQTGAGIVGGAGGSAGLIGNGGAGGTGGAGATGGAGGNGGWLFGSGGIGGTGGANALGTGGTGGLGGSAGLFGGGGNGGAGGLGISGDLGTGGAGGTGGFLLGDYGVSGAGGDGRTVPLEVVNVTEPVVNVNVNGGHSTPVLIDTGSAGLVMQVKDVGGPLGLLRMGLPSGISMSAYSGGLTYLFATYPTTVDFGNGIVTSTTGVDVVLFSIPTSPYALTTWLNALWSNPLTTPFDAYFQSAGVDGVLGVGPNAVGPGPSIPTQALGGGLGQGLLIDMKGGELVFGPNPLTPEFSISGAPIATLWVSVNGGAPVAVPSIIDSGGVMGTIPSSVIGGSTLPANTNITVYTDNTMTTEVYHYSTNDYQPTVISSGLMNTGFLPFWNQPVYIDYSPAGTGTTVFDMP",
    "output": "Aspartic protease that processes the lipase LipY and other PE_PGRS proteins. Can also cleave itself. Cleaves LipY both inside the PE domain, before amino acid 98, and after amino acids 136 and 149. Involved in virulence."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNLIYNFSAGPAMIPKDVLYQAKKELQNWNQIGCSIMEISHRSKEFIQVALEAEQDLRDLLNISNSYEILFCQGGARGQFAAVPMNLLGNFKETDYINSGYWSNCALIEAKKYCIPKNISVRQKKNGKSFLLKPSQWNISDNSAYIHYCPNETIDGMSIYEEPNFKNKIIVGDFSSFILSRRINIENYGLIYAGAQKNIGPSGITIILIRKDLIGYASKISPSIFNYYIISKYNSMFNTPPTFSWYLSGLVFKWLKKQGGIKKIEQLNQKKSNLLYQIIDNSNFYINDIDKRNRSQMNVVFHLYNSKLDNLFLKEAKNAGLNALKGHNVIGGMRASIYNAMPLEGVQSLAKFMLYFEKKYG",
    "output": "Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAVVKEVLEIAEKIKNMEIRGAGKIARSAAYALQLQAEKSKATNVDEFWKEMKQAAKILFETRPTAVSLPNALRYVMHRGKIAYSSGADLEQLRFVIINAAKEFIHNSEKALERIGEFGAKRIEDGDVIMTHCHSKAAISVMKTAWEQGKDIKVIVTETRPKWQGKITAKELASYGIPVIYVVDSAARHYMKMTDKVVMGADSITVNGAVINKIGTALIALTAKEHRVWTMIAAETYKFHPETMLGQLVEIEMRDPTEVIPEDELKTWPKNIEVWNPAFDVTPPEYVDVIITERGIIPPYAAIDILREEFGWALKYTEPWED",
    "output": "Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Only accepts the alpha-anomer of D-ribose 1,5-bisphosphate as substrate, being inactive on the beta-anomer. Displays a strict substrate specificity, since other phosphorylated sugars such as R5P, ribose, G16P, G6P, G1P, FBP, F6P, and PRPP, are not substrates. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTEVELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATDKNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAADFLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE",
    "output": "Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNIPGMTTGMAPAGATAGAGFPGAGAGMQGMSEQEQAMVKAMHAAMESCPVKTVISGTMGFGLGGVFGLFMASMSYDSTFTPQGKAIMDLPWREQVRRGFKDMGSRSWSSAKNFGIVGALYSGTECCVEGLRAKNDLSNSVISGCITGGILGAKAGPQAAAAGCAGFAAFSAAIDAYMRMPSEE",
    "output": "Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTTSTGKINLLGLTQPEMEQFFDSIGEKRFRAGQVMKWIHHFGVSDFAAMTNVGKVLREKLEAVAEIRPPEVVSEDISADGTRKWVIRVASGSCVETVYIPTDDRGTLCVSSQAGCALDCSFCSTGKQGFNSNLTAAEVIGQVWLANKSFGTVPAKVDRAITNVVMMGMGEPLLNFDNVIAAMKIMMDDLGYGISKRRVTLSTSGVVPMIDELAKHIDVSLALSLHAPNDELRNKLVPINKKYPLKVLLESCMGYMSTLGGKRVLTVEYTLLKDVNDQPEHAAQMIELLRDVPCKINLIPFNPFPHSGYERPSNNAIRRFQDLLHHGGFNVTTRTTRGDDIDAACGQLVGQVNDRTRRSERYIAVRQLSADVELPDSAASH",
    "output": "Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKRISPLNTLFYLSLFFSYTFKGLKCTRIYKIGTKALPCSECHDVFDCTGCLFEEKESSHVIPLKLNKKNPNDHKKLQKHHESLKLGDVKYYVNRGEGISGSLGTSSGNTLDDMDLINEEINKKRTNAQLDEKNFLDFTTYNKNKAQDISDHLSDIQKHVYEQDAQKGNKNFTNNENNSDNENNSDNENNSDNENNLDNENNLDNENNSDNSSIEKNFIALENKNATVEQTKENIFLVPLKHLRDSQFVGELLVGTPPQTVYPIFDTGSTNVWVVTTACEEESCKKVRRYDPNKSKTFRRSFIEKNLHIVFGSGSISGSVGTDTFMLGKHLVRNQTFGLVESESNNNKNGGDNIFDYISFEGIVGLGFPGMLSAGNIPFFDNLLKQNPNVDPQFSFYISPYDGKSTLIIGGISKSFYEGDIYMLPVLKESYWEVKLDELYIGKERICCDEESYVIFDTGTSYNTMPSSQMKTFLNLIHSTACTEQNYKDILKSYPIIKYVFGELIIELHPEEYMILNDDVCMPAYMQIDVPSERNHAYLLGSLSFMRNFFTVFVRGTESRPSMVGVARAKSKN",
    "output": "During the asexual blood stage, processes key proteins essential for merozoite egress and invasion of host erythrocytes . Cleaves and activates proteases SUB1 and SUB2 . May process members of the EBL and Rh protein families . Also cleaves apical membrane protein AMA1 . During the mosquito vector stage and probably in ookinetes, cleaves CelTOS ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVCGCSALLPLPNPRPTMPATPNFLANPSSSSRWIPLQPMPVAWAFVQKTSALLWLLLLGTSLSPAWGQAKIPLETVKLWADTFGGDLYNTVTKYSGSLLLQKKYKDVESSLKIEEVDGLELVRKFSEDMENMLRRKVEAVQNLVEAAEEADLNHEFNESLVFDYYNSVLINERDEKGNFVELGAEFLLESNAHFSNLPVNTSISSVQLPTNVYNKDPDILNGVYMSEALNAVFVENFQRDPTLTWQYFGSATGFFRIYPGIKWTPDENGVITFDCRNRGWYIQAATSPKDIVILVDVSGSMKGLRMTIAKHTITTILDTLGENDFINIIAYNDYVHYIEPCFKGILVQADRDNREHFKLLVEELMVKGVGVVDQALREAFQILKQFQEAKQGSLCNQAIMLISDGAVEDYEPVFEKYNWPDCKVRVFTYLIGREVSFADRMKWIACNNKGYYTQISTLADTQENVMEYLHVLSRPMVINHDHDIIWTEAYMDSKLLSSQAQSLTLLTTVAMPVFSKKNETRSHGILLGVVGSDVALRELMKLAPRYKLGVHGYAFLNTNNGYILSHPDLRPLYREGKKLKPKPNYNSVDLSEVEWEDQAESLRTAMINRETGTLSMDVKVPMDKGKRVLFLTNDYFFTDISDTPFSLGVVLSRGHGEYILLGNTSVEEGLHDLLHPDLALAGDWIYCITDIDPDHRKLSQLEAMIRFLTRKDPDLECDEELVREVLFDAVVTAPMEAYWTALALNMSEESEHVVDMAFLGTRAGLLRSSLFVGSEKVSDRKFLTPEDEASVFTLDRFPLWYRQASEHPAGSFVFNLRWAEGPESAGEPMVVTASTAVAVTVDKRTAIAAAAGVQMKLEFLQRKFWAATRQCSTVDGPCTQSCEDSDLDCFVIDNNGFILISKRSRETGRFLGEVDGAVLTQLLSMGVFSQVTMYDYQAMCKPSSHHHSAAQPLVSPISAFLTATRWLLQELVLFLLEWSVWGSWYDRGAEAKSVFHHSHKHKKQDPLQPCDTEYPVFVYQPAIREANGIVECGPCQKVFVVQQIPNSNLLLLVTDPTCDCSIFPPVLQEATEVKYNASVKCDRMRSQKLRRRPDSCHAFHPEENAQDCGGASDTSASPPLLLLPVCAWGLLPQLLR",
    "output": "The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIQMQSRLSVADNSGARELQCIKVLGGSHRRYAGIGDVIKVSVKDAMPRGRVKKGDVYNALIVRTKKGVRRRDGSVLRFDGNAAVLLNSKLEPIGTRVFGPVARELRSEKFMKIISLAPEVL",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDKKAARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNGSEILVAASTVEKAINEQLKYAGNKDAAAAVGKTIAERALEKGITKVSFDRSGFQYHGRVQALADAAREAGLQF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARYRRHSRSRSRSRYRRRRRRRSRGRRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRRY",
    "output": "Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MELLEERIKKDGVVLPGNVLKVNSFLNHQIDPQLMMTLGQEFARLFKDAGVTRVLTAEASGIAPGIMAAYCLGVPMVFARKKKPSTVTDAVYTAEVFSYTKQVTNTISVEAKFLDANDRILVIDDFLANGEAAKGLISLAEQAGAEVVGVGVVVEKAFQGGHDWLVNHGYHLEALASIKEFADGQVIFN",
    "output": "Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIRNSMKSHTELLSWNLLQKEADRVRLNSDSLTCVVPDSNNYESSKQINCIEYDYSRQRVNRTIIDLLIDLANEVKLQEKIDNLINGKKINISENRPALHTALRDLGNKSIMIDGLDIMSAVINTREKIKVISNQIREKKWLGHSGLPITDIVNIGIGGSDLGPRVCINALSNYISKEFNYHFISDVDPASFNDVIAKINPQTTLFIVSSKSFTTKETLLNARKAFALYEDTASIDQHFIAVTAHPERAYQMGIKTVLPIWDWVGGRFSFCSAVNLITAIAIGYEQFVELLAGAHDVDTHVQFTDFKNNIPVLMALIGIWNNNFLNIHNLLILTYSKKLEYFVPYVQQLDMESNGKSIDVNGSMVDYATGPIVWGGLGNQAQHSYFQLLCQGTHRCVGDFITLKTNDEHEINSMCHYKMKVLSEGIQTIENPYGYIPGNMPMNHLILSDCSPYTLGALVALYEHKIFVQSVIWNINPFDQPGIESAKSAHREITLSSES",
    "output": "Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKSAAIITFLFAALVLFAAFEAPIMVEAQKLCEKPSGTWSGVCGNSNACKNQCINLEGAKHGSCNYVFPAHKCICYFPC",
    "output": "Confers broad-spectrum resistance to pathogens. Has antifungal activity in vitro."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRIEKDKELMNILKIMAPGTPLREGLENILRAKTGGLLILGDSDQILKLVDGGFKINSEYSPSYVYELAKMDGSIVLSSDLKKILCANAQLIPDSSIPTFETGTRHRTADRVAKQTGAIVIAISQRRNIITVYKGGIKYVLRDSSIILARANQALQTLEKYVAVLDRVVNNLNILEFKDIATLFDVVTAIQRSEMVMRIVSEIERYICELGNEGRLIDMQLSELIKSVEEDGILLIRDYCRSNMEYEDIYKQIQGLSSEELLNLDGLSKIIGYTGVPLVDTLISPRGYRMINKIPRIPSNVIENLVANFNQLKCVMEASYEQLDNVEGIGEARAKAIKNGLRRLREQIMLDKV",
    "output": "Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEAKVEKIETNVVKLEIKVEAEKFDAALTKAYNKNKGKYNVPGFRKGKVPMAILKKMYGIEIFYDDAVNIAIDESYNEALKAEDIRPVDYPKVDIVEIGEGKELVYTATVTTYPEVEIGEYKGLDIKKPSYEVSEEEVEKQVKEMQSKNARIETKEEGTIADGNIAIIDFKGFVDGEAFEGGEGTDYPLEIGSGTFIDNFEEQLIGLAIGDKKEVNVTFPENYGKEELNAKPAMFEVTVKGIKAKELPELDDEFAKEVSEFDTLAELKENIKKRLEESNDERAEREFEEAVITSIIETSKIDLPEVMLTKEIDSMMKDLESRLQYQGLSLDQYMEFTGNTMEKMREFMKENAERKVKADIILESVAKAEDVKATDEQLNERALELGRMYGPKDPKKMANILLKAQKGMIEKDIIIENTLKLIKESCK",
    "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRASR",
    "output": "Multidrug efflux pump that functions probably as a Na(+)/drug antiporter."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSGFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIEAAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRHTWGRAPQAEVLTPGYKYNLTDINAAIALTQLVKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ",
    "output": "Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MICLKILRFYQKFLSPLKPAACRYYPSCSEYALWQFQKKNFFLAFLSTFFRILRCNPFFKGGFDYPKVSKNFYPMNLCFKPMFLAKKQLCFLYIPYKNKSFYLIKIIFKRTNQ",
    "output": "Could be involved in insertion of integral membrane proteins into the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIPLQHGLILAAILFVLGLTGLLVRRNLLFMLISLEVMINAAALAFIVAGSYWGQPDGQVMYILAISLAAAEASIGLALLLQLYRRRHTLNIDTVSEMRG",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALSPNSSSLDLTISIPSFSPSPSLGDHHGMRDFDINQTPKTEEDREWMIGATPHVNEDDSNSGGRRRKKLRLTKEQSHLLEESFIQNHTLTPKQKKDLATFLKLSQRQVEVWFQNRRARSKLKHTEMECEYLKRWFGSLKEQNRRLQIEVEELRALKPSSTSALTMCPRCERVTDAVDNDSNAVQEGAVLSSRSRMTISSSSSLC",
    "output": "Probable transcription factor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARYRCCRSQSRSRCRRRRRRCRTRRRRCCRRRRRRVCCRRYTVVRCRRR",
    "output": "Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSILKKSLFLVLFLGLVSFSICEEEKREAEEEENEDEIEEESDEKKRESPDRPPGFSPFRIY",
    "output": "Produces in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle (By similarity). May target bradykinin receptors (BDKRB)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MALSAEGSSGGSRGGSPKAEAASVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI",
    "output": "Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGIPFSDPLADGPTIQEANIRALESGITPKDCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCLDAGVDSILIADVPAHESKEFRDIAKKVGIAQIFIAPPDASESTLKQISELGSGYTYLLSRVGVTGTETAANMPVEDVLTKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVKIIQNNISNKQKMLNELTYFVKEMKAATLN",
    "output": "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSASDGNTAELWVPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVVSAPTEV",
    "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEQNNTEMAFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQAGIFSISGIEGTQMAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA",
    "output": "One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRFEDIGISKVDKVCLVDRLGCQENLVGTVHVTTTHIIFRAENGSKELWLATGLISSVEKGTLTAAGCMLVIRCKHFQVITLLISRDKSCQDLYETLQRAAKPVSVNVTELLAFENREPVEDVRGWRRLDWNSEMTRQGITKSQWTESNINEGYTICDTYPNKLWFPTAASTSVLLGSCKFRSRGRLPVLTYFHQQTEAALCRCAQPLTGFSARCVEDEKLMELVGKANTNSDNLFLVDTRPRVNAMVNKVQGKGFEDERNYSNMRFHFFDIENIHVMRASQARLLDAVTKCRDVTEYWKTLEASGWLKHVRSVVECSLFLAESISRGTSCVVHCSDGWDRTSQVVALCQLLLDPYYRTIHGFQVLIEKDWLGFGHKFDDRCGHVGALNDEAGKEVSPIFTQWLDCIWQIMQQKPRAFQFNERYLIEMHEHVYSCQFGTFIGNCDKDRRDLNLSKRTKSLWTWMDARHDDYMNPFYSPTAHVALLDLDTRAARFTVWTAMYNRFDNGLQPRERLEDLTMAAMEHVGVLESHVAQLRTRLAELKTQQNQQITSTNTPTNMVDSGMSSATDDLKNLSLSHPLDPLSSTLPILERATSQESGVMDSSLYYPDEALTKYSLKWQPLRGADRCSNPACRGEFSSTIERRIHCHLCGMIFCRRCLKVSADERERVCDKCKTD",
    "output": "May dephosphorylate phosphatidylinositol-3-phosphate (PI3P) . In association with mtm-9, plays a role in endosome trafficking probably by regulating phosphatidylinositol-3-phosphate levels . Regulates fluid phase endocytosis in coelomocytes . Controls the endosomal localization of sorting nexin snx-3 and the levels of sorting receptor mig-14 . By regulating the retrograde transport of mig-14, may be involved in the secretion of Wnt ligands such as egl-20 . Regulates posterior migration of QL neuroblast descendants and the anterior migration of QR neuroblast descendants and HSN neurons during larval development . Involved in the formation of correct synapse number in DA9 motor neurons probably in part by regulating the secretion of Wnt ligand egl-20 ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTDKTPFYITTAISYPNGKPHIGHAYELIATDAMARFQRLDGMDVFFLTGTDEHGQKMQQTARAEGISPEELAQRNSDQFREMGKLLNASNDDFIRTTEERHHETSRNIWNLMADSGDIYKDSYAGWYSVRDEAYYAEDETEVRADGVRYGPQGTPVEWVEEESYFFKLSEYQEKLLKLYEENPDFIGPAERRNEIISFVKSGLKDLSISRTTFDWGIKVPDDPKHVMYVWVDALTNYITATGYIEDRNGPRAKYWPADVHIIGKDIIRFHAVYWPAFLMSAKLPLPKRVYAHGFLLNKGEKMSKSLGNVVDPANLVAHFGLDPVRYFFMREVSFGQDGSYSEEGIATRINADLANGIGNLASRSLSMIVKNCDGQIPTPGAFNDDDKAMLASADGLLAVCREEMGKQLIHRALAAIIAVVSETDRYFASQEPWALKKTDPERMGTVLYVTAEVVRQIGILLQPFMPQSCEKLLDLVAAPADGRDFTALGEAGRLAPGTPLEAPKPVFPRYVAPEA",
    "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDLLIRLGFLLMCALPTPGERSSRDPKTLLSLSPRQACVPRTKSHRPVCYNDTGDCTDADDSWKQLGEDFAHQCLQAAKKRPKTHKSRPNDRNLEGRLTCQRVRRLLPCDLDIHPSHRLLTLMNNCVCDGAVWNAFRLIERHGFFAVTLYLCCGITLLVVILALLCSITYESTGRGIRRCGS",
    "output": "Inhibits peptide loading of MHC class I molecules by transporters associated with antigen processing (TAP). Does not prevent peptide binding to TAP, but binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1, but not TAP2. Also prevents the conformational rearrangement of TAP induced by peptide binding. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTHLLIVDDEQDIVDICQTYFEYEGYKVTTTTSGKEAISLLSNDIDIMVLDIMMPEVNGYDIVKEMKRQKLDIPFIYLTAKTQEHDTIYALTLGADDYVKKPFSPRELVLRINNLLTRMKKYHHQPVEQLSFDELTLINLSKVVTVNGHEVPMRIKEFELLWYLASRENEVISKSELLEKVWGYDYYEDANTVNVHIHRIREKLEKESFTTYTITTVWGLGYKFERSR",
    "output": "Member of the two-component regulatory system SaeR/SaeS involved in the regulation of staphylococcal virulence factors in a strain-dependent fashion. Probably functions as a transcriptional regulator via a specific DNA-binding domain, recognizing motifs near the promoter sequences of target genes (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAQGSVSFNDVTVDFTQEEWQHLDHAQKTLYMDVMLENYCHLISVGCHMTKPDVILKLERGEEPWTSFAGHTCLEENWKAEDFLVKFKEHQEKYSRSVVSINHKKLVKEKSKIYEKTFTLGKNPVNSKNLPPEYDTHGRILKNVSELIISNLNPARKRLSEYNGYGKSLLSTKQETTHPEVKSHNQSARAFSHNEVLMQYQKTETPAQSFGYNDCEKSFLQRGGLITHSRPYKGENPSVYNKKRRATNIEKKHTCNECGKSFCRKSVLILHQGIHSEEKPYQCHQCGNAFRRKSYLIDHQRTHTGEKPFVCNECGKSFRLKTALTDHQRTHTGEKSYECLQCRNAFRLKSHLIRHQRTHTGEKPYECNDCGKSFRQKTTLSLHQRIHTGEKPYICKECGKSFHQKANLTVHQRTHTGEKPYICNECGKSFSQKTTLALHEKTHNEEKPYICSECGKSFRQKTTLVAHQRTHTGEKSYECPHCGKAFRMKSYLIDHHRTHTGEKPYECNECGKSFSQKTNLNLHQRIHTGEKPYVCNECGKSFRQKATLTVHQKIHTGQKSYECPQCGKAFSRKSYLIHHQRTHTGEKPYKCSECGKCFRQKTNLIVHQRTHTGEKPYVCNECGKSFSYKRNLIVHQRTHKGENIEMQ",
    "output": "May be involved in transcriptional regulation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MERITVTLGERSYPITIAAGLFNDPASFMPLKAGEQVMLVTNQTLAPLYLDHVRKVLEQAGVMVDQVILPDGEQYKSLAVLEQVFSALLEKPHGRDTTLIALGGGVIGDLTGFAAACYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPVSVVVDLDCLKTLPARELSSGLAEVIKYGIILDHDFFVWLENNIDALVALDMQALAYCIRRCCELKAEVVAADERESGLRALLNLGHTYGHAIEAEMGYGVWLHGEAIAAGMVMAAETAHRLGQFSREDIERIKALLLRAGLPVCGPQEMAPGTYLPHMMRDKKVLAGELRLVLPTAIGQAEVRGGVGHDMVLASIAACFPDGMSK",
    "output": "Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDKKLARIRRATRTRQKIKELGTTRLVINRTSRHIYAQIISPTGSEVLVAASSVEKVINQEFKYSGNKEAAAFVGKIIAERALKKGIIKVSFDRSGFQYHGRVQALADNAREAGLNF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTITPQQLIAMLPLLIVGLTVVVVMLSIAWRRDHFINATLTVIGLNLALLSLYFVGQVGPMDVTPLMRVDGYSMFYTGLVIIASLATSTFAYPWLVGYPDNREEFYLLVLIAALGGILLASANHLASLFLGIELLTLPLFGLIGYAYRQKRSLEASIKYMLLSAAASSFLLFGMALLYAESGSLSFVGLGQSLSDSMVHQPLILAGLGMMIVGLGFKLSLVPFQLWTPDVYQGAPAPVSTFLATASKIAIFAVVMRLFMYAPAADSEAVRLVLSIIAVASILFGNLMAISQTNIKRLLGYSSIAHLGYLLIALVAVQTHELALPLETIGVYLAGYLFSSLGAFGVVSLMSSPYKGPDAESLFSYRGLFWHKPILSAVMTVMMLSLAGIPMTLGFIGKFFVVAMGVSANLWWLTGAVVLGSAIGLYYYLRVTVSLFLSPPQSLVRDTPSNWALTAGGVVVLISAILVLVLGIYPQPLITLVQMAQPLM",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDIWRNFAD",
    "output": "Modulates RecA activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSQSYINVVGAGLAGSEAAYQIAKRGIPVKLYEMRGVKRTPQHKTSNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRTGEAHRVPAGGAMAVDRSGYAQAVTAELENNPLIQVIRNEVTEIPDDAITVIATGPLTSDSLAKKIYKLNGGEGFYFYDAAAPIVDQSSIDMDKVYLKSRYDKGEAAYLNCPMTKEEFIRFYEALINAEEAPFNSFEREKYFEGCMPIEVMAKRGIKTLLYGPMKPVGLEYPQDYKGPRDGDYKAPYAVVQLRQDNAAGSLYNIVGFQTHLKWSEQKRVFSMIPGLEQAHFVRYGVMHRNSYIDSPNLLAPTFATCKNPNLFFAGQMTGVEGYVESAASGLVAGINAVRRFKDEEAVIFPQTTAIGALPYYITHTKSKHFQPMNINFGIIKDLGGPRIRDKKKRYEKIAERSLKDLQQFLTV",
    "output": "Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "KVYGRCELAAAMKRLGLDNYRGYSLGNWVCAAKFESNFNTHATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSGGSGMNAWVAWRNRCKGTDVQAWIRGCRL",
    "output": "Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKSTAEIRQAFLDFFHSKGHQVVSSSSLVPNNDPTLLFTNAGMNQFKDVFLGLDKRAYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAINFAWELLTSEQWFNLPKEKLWVTVYETDDEAYNIWANEVGVPHERIIRIGDNKGGAFASDNFWQMGDTGPCGPCSEIFFDHGDHIWGGPPGSAEEDGDRYIEIWNIVFMQFNRQSDGTMLPLPKPSVDTGMGLERIAAVLQHVNSNYEIDLFRDLIAAVADVTGATDLSSKSLRVIADHIRSCAFLISDGVIPSNENRGYVLRRIIRRAIRHGNMLGAKETFFYKLVAPLIAVMGPAAAELKQQQAMVEQVLKTEEEQFARTLERGLALLDDELSKLTGDTLDGETAFRLYDTYGFPVDLTADVCRERNLKVDEAGFEQAMEAQRRRARESSGFGADYNSLIRVDSASQFSGYDHVQQHATVTALFRNGEAVDEIHAGEEAVVVLNRTPFYGESGGQVGDKGELKNATATFSVTDTQKYGQAIGHVGILTTGTLRVNHSVEALVDVVRRNRIRLNHSATHLLHAALRNVLGEHVAQKGSLVNDKYLRFDFSHFEAMKPEQIRLVEDLVNEQIRRNMPVQTEVMELDAAKEKGAMALFGEKYDDQVRVLTMGDFSTELCGGTHASRTGDIGLFRILTESGTAAGIRRIEAVTGEGAIALLHQQSDLLQDVAHLVKGDIHNLADKVRAVLDRSKMLERELQQLKDQQAAQESASLSSSAKLINGVKLLVSQLDNVEPKMLRTMVDDLKNQLGSAIIVLATTADDKVSLIVGVTKDLTGKVKAGELIADIAQQVGGKGGGRPDMAQAGGTDVQALPAALASVEAWVASRM",
    "output": "Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAIQLTRRGALSLLLFLTPAVMPTWYAGSGYYPDESYNEVYAEEVPQTPILDYKVPRWCYTLNIQDGEATCYSPRGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPVVKDSADGTITRLTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPLHGYLTCTSAGDNYGATCEYHCDGGYERQGTSSRVCQSSRQWSGSPPVCVPMKINVNVNSAAGLLDQFYEKRRLLIISAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREHQLSANIIEELRQFQHLTRSYFNMVLIDKQGIDRERYMEPVTPEEIFTFIDDYLLSNEELIQRREQRDICD",
    "output": "Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MYYGFDVGGTKIEFGAFNEKLERVATERIPTQTEDYSLLVNDIASLIAKYDAEFGVEGKVGLGIPGMEDAETGALLTSNVPAAKGQFLRKDLEAKIGRSVKIDNDANCFALSEAWDEELKDSPSVLGLILGTGFGGGLVFDGKVFSGYSHVAGELGHSRLPIDAWFHLGEKAPLLECGCGNKGCIDNYLSGRGFELLYAHYYGQEKKAIDIIKANEAGDADAVEHVDRFMELLAICFANLFTCFDPHVVALGGGLSNFALIYDELPKRLPKHLLSVARVPRIIKAKHGDSGGVRGAAFLNIK",
    "output": "Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKISLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKYDMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE",
    "output": "Required for resistance to DNA-damaging agents."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAQERREGGRGREREERDDGMVDKLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATESAKRDMIFVPLRSGRTLHHDVEGRWGAGRVLLRAAKQGTGIIAGGPMRAVFETLGMHDVVAKSMGSSNPYNMVRATFDALKSQMHPKDVAAARGIKYSTLQARRGTAVAAEE",
    "output": "With S4 and S12 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDKNFYKNSLNIFNSNFSMKANLSEKDKFYADFWEKNQIYQQILRKRRGNPRFILHDGPPYANGDIHIGHALNKILKDIIVRYKTMAGFYSPFVPGWDTHGLPIENKIINQIGSKSTLEIRRKSNDFANSQILAQMAQFKKLNLLTDFKQIYQTNTPNYEAKQLKLFKKMVSRGLVYRALKPVYWSPSSQSALAEAEIEYLEYRSPSLFTSFDIKKGNNFVAENDKLIIWTTTPWTLIANSGVAVGENFDYVRIKNEENFYVLAANLLEKLAAIFDWKHYEIIDNFPGKSILGIKYLHPIFEKICPIVSGNHVSLDVGSGLVHLAPLFGEDDYWIGRENNLEMVMHVNDDGKFNENAGQFSGQFYANSNKLITEFLEKKSKILHLSFIDHSFPHDWRTLKPVIYRGTPQWFVSIEKIKKDLEKAIEEIEFPENWLKKRLTKMVVERKDWLISRQRSWGIPLIIFYDQNKEPVLDKPEIFDYIISLVEKFGSRIWYEKTTDELLPEKYQNLGWTKENDILDVWFDSGVSFFAANISDEKPPFDIYFEGSDQYRGWFNSSLINSVIYFGFSPYKKLLSHGFVVDAKGNKMSKSRGNGVDPLVILSKYGCDIFRLWVANSEYYNDIVYSEAIFEQNVEIYRKIRNTVRFLITNLADFKPKKYELTEVDLYIFNKIQKLKNEIIQNYDQNRFVRVVKIINNFIIEFSNFYLSIVKDILYADKKESLKRRQVQYNLYELLQVLNIAIAPIMPTTAEEIYSFIQKNNKQISVHMEEFFKESHFDEELVAKWDEFFQIKDSVYQLIEQKIKSKEIKRPNEVGVLLKTDSDFIKSIDLEKLLMVAKVEFSNEKTEILQLNWEKCPRCWNHFEKINKVCARCFEVLSEIVPEKNS",
    "output": "Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "VIGGDICNINEHNFLVALYE",
    "output": "Thrombin-like snake venom serine protease that coagulates human plasma and bovine fibrinogen by hydrolysis of the alpha chains (FGA) (minimum coagulation dose is 60 ug on fibrinogen). Has fibrinogenolytic activities, and degrades preferentially the Aalpha chain (FGA). Shows amidolytic activity toward N-benzoyl-L-Arg-p-nitroanilide, has a higher activity than Cdc SI. In vivo, intravenous injection induces defibrin(ogen)ation and a loss of the righting reflex and opisthotoxins, together with a typical gyroxin-like effect (18-20 minutes). Subcutaneous injection into the footpads induces moderate edema. Potentiates local hemorrhagic activity induced by metalloproteinases (BaP1)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPTINQLVRKPRQSKIKKSDSPALNKGFNSKKKKFTDLNSPQKRGVCTRVGTMTPKKPNSALRKYARVRLSNNIEINAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDTSGVDGRRQGRSLYGTKKPKN",
    "output": "With S4 and S5 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLKSVIENVHALEIFDSRGNPTVEVHVTLSNGVVGKAEVPSGASTGENEAVELRDGGSRLGGKGVSKAVNNVNTEINDALKGMDPFDQPKIDQTMIDLDGTPNKGRLGANAILGVSMATAVAAANANRQPLYRYLGGIDLEMPQTFHNVINGGEHADNGIDIQEFMITPIAKTSFRDGFEKIVNVYHTLKKVLEDMGYETGLGDEGGFAPNMKNSEEALKALHESIIKAGYKPGEDIGIACDCAASYFYNKEDGKYHLEGKVLTDDELAAYYDKLLDEFPELMSMEDPYDENDVEGMVKFTATHKDRIQIVLDDFICTNPALLKKAIKEGAGNASLIKLNQIGTVTETLETIRMSRKNGYNTMISHRSGETGDTFIADLAVAINGGQLKTGAPARSERVEKYNRLLEIEEELGKGERLAFFPDDVDHD",
    "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVEDNTYYNVEFIELLSDKHLDYEKETGVFELTEF",
    "output": "A non-essential component of RNA polymerase (RNAP)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIKALFNKNTALAAVAILALSGGAMAESAKTHKTDMAKKKVSELTCEDFNGLEESFKPTVVGWVVGFNKKGKEEDAVIDVDGIETVTPAIIEACKQEPKASFWKKAEAELKKVF",
    "output": "Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA",
    "output": "The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKQYLDLMRHVRDTGTKKEDRTGTGTVSVFGYQMRFDLSEGFPLVTTKKCHLKSIIHELLWFLKGETNTQYLTDNGVRIWNEWATEEGDLGPVYGAQWRSWPTPDGGSLDQFALLVEQIKNKPDSRRHIISAWNPALLPDEGVSPQDNVRNGKMALPPCHTLFQFYVADNKLSCQLYQRSADIFLGVPFNIASYALLTMMVAQVTGLELGDFVHTFGDAHLYLNHLEQVETQLAREPLPLPTMKINPEVKDIFSFKFEDFELVDYQAHPHISAPISI",
    "output": "Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGETTVEVRKVKNYINGKWIESSTSLYEDVVNPATKEVICQVPLSTKADVEYAVEAAKTAFAKWSKVAVPRRARILFNYQQLLQRDKEELARLITIENGKNLTEARGEVQRGIENVEFAAGAPSLMMGDSLPMIATDVEASNYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNAFLLKPSERTPLLTEKLADLLTEAGVPDGVFNVVYGAHDVVNGMLEHPDIKAISFVGSKPVGEYVYKKASENLKRVQALTGAKNHTIVLNDADLDDAVTNIAGAAFGSAGERCMACAVVTVEEGIADAFVAKLKAKAESLVMGNGLDDGVFLGPVIREENKNRTIAYIEKGVEEGATLVCDGRSRVSADGYFIGPTIFENVTTDMTIWKDEIFAPVLSIIRVKNLDEGIQIANRSEFANGACLFTTNAAAVRYFRENIDAGMLGINLGVPAPMAFFPFSGWKSSFYGTLHANGKDSVDFYTRKKVVTARYPKPSFD",
    "output": "Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRILGLDVGTKTVGVAISDEMGWTAQGLETIKINEERGQFGFDRISELVKQYDVDKIVVGLPKNMNGTIGPRGEACQQFAENLRELLQLDVVMWDERLSTMAAERLLISADVSRKKRKQVIDKMAAVVILQGFLDSK",
    "output": "Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVTINISNPVYFSDIKDVESEFLTSIPNGLTHEEAQNRLSEYGENRLEADSGVSAWKVLLRQVLNAMCVVLILAAALSFGTTDWIEGGVISAIIVLNITVGFIQEYKAEKTMDSLRTLASPMAHVTRSSKTDAIDSHLLVPGDVVVLKTGDVVPADLRLVETVNFETDEALLTGESLPVIKDAHATFQMNEDVPIGDRINLAYSSSIVTKGRAKGICYATGMQTQIGAIAAGLRQKGKLFQRPEKDEPNYRRKLNKYYLKVTSYYVQRVLGLNVGTPLQRKLTVLAYILFCIAIILAIIVMAAHSFHVTNEVSIYAISLGISIIPESLIAVLSITMAMGQKNMSKRRVIVRKLEALEALGGVTDICSDKTGTITQGKMITRRVWIPSYGYLSVDTSDANNPTIGTVSGLEAAMQDVLKEKKQEMKNIDPSNQPSDQFIPLLKTCALCNLSTVNQTETGEWVVKGEPTEIALHVFSKRFNYGKEDLLKTNTFVREYPFDSEIKRMAVIYEDQQGQYTVYAKGAVERILERCSTSNGSTLEEPDRELIIAQMETLAAEGLRVLALATKVIDKADNWETLPRDVAESSLEFVSLVGIYDPPRTESKGAVELCHRAGIRVHMLTGDHPETAKAIAREVGIIPPFISDRDPNMSWMVMTGSQFDALSDEEVDSLKALCLVIARCAPQTKVKMIEALHRRKAFVAMTGDGVNDSPSLKQANVGIAMGQNGSDVAKDASDIVLTDDNFSSIVNAIEEGRRMFDNIMRFVLHLLVSNVGEVILLVVGLAFRDEVHLSVFPMSPVEILWCNMITSSFPSMGLGMELAQPDVMERLPHDNKVGIFQKSLIVDMMVYGFFLGVVSLMTWVVIMYGFGTGNLSYDCNAHYHAGCNDVFKARSAVFAVVTFCILIMAVEVKNFDNSLFNLHGIPWGEWNFRYFLHTLVENKFLAWAIALAAVSVFPTIYIPVINRDVFKHTYIGWEWGVVAVAVMFYFFYVEIWKSIRRSLTNPQKKGKFRRTLSNTITTESKLSEKDLEHRLFLQSRRA",
    "output": "Catalyzes the hydrolysis of ATP coupled with the export of sodium and potassium from the cell . May export sodium less efficiently . May transport other cations such as lithium (By similarity). Sodium/potassium efflux ATPases are involved in salt tolerance and maintaining the membrane potential across the plasma membrane in high salinity (Na+) or alkaline (K+) environments ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "ASYKVKLITPDGPIEFDCPDDVYILDQAEEAGHDLPYSCRAGSCSSCAGKIAGGAVDQTDGNFLDDDQLEEGWVLTCVAYPQSDVTIETHKEAELVG",
    "output": "Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPVAYTFPVLPSSCLLCGISNRSTSFVVDRPELQISGLLVVRSESGEFFGSGLSLRRFQREGRRRLNAAGGGIHVVDNAPSRTSSLAASTSTIELPVTCYQLIGVSEQAEKDEVVKSVINLKKTDAEEGYTMEAAAARQDLLMDVRDKLLFESEYAGNLKEKIAPKSPLRIPWAWLPGALCLLQEVGQEKLVLDIGRAALRNLDSKPYIHDIFLSMALAECAIAKAAFEVNKVSQGFEALARAQSFLKSKVTLGKLALLTQIEESLEELAPPCTLDLLGLPRTPENAERRRGAIAALRELLRQGLSVEASCQIQDWPCFLSQAISRLLATEIVDLLPWDDLAITRKNKKSLESHNQRVVIDFNCFYMVLLGHIAVGFSGKQNETINKAKTICECLIASEGVDLKFEEAFCSFLLKQGSEAEALEKLKQLESNSDSAVRNSILGKESRSTSATPSLEAWLMESVLANFPDTRGCSPSLANFFRAEKKYPENKKMGSPSIMNHKTNQRPLSTTQFVNSSQHLYTAVEQLTPTDLQSPVVSAKNNDETSASMPSVQLKRNLGVHKNKIWDEWLSQSSLIGRVSVVALLGCTVFFSLKLSGIRSGRLQSMPISVSARPHSESDSFLWKTESGNFRKNLDSVNRNGIVGNIKVLIDMLKMHCGEHPDALYLKSSGQSATSLSHSASELHKRPMDTEEAEELVRQWENVKAEALGPTHQVYSLSEVLDESMLVQWQTLAQTAEAKSCYWRFVLLHLEVLQAHIFEDGIAGEAAEIEALLEEAAELVDESQPKNAKYYSTYKIRYILKKQEDGLWKFCQSDIQIQK",
    "output": "Component of the plastid division machinery required for PDV1 localization to constriction sites. Involved in chloroplast division site placement . Required for the proper formation of FtsZ rings at the division site in nongreen plastids (e.g. etioplasts) . Inhibits FtsZ assembly, functioning as an antagonistic regulator of FtsZ dynamics against ARC6, by recruiting ARC3 to the middle of the plastid to facilitates its interaction with FtsZ proteins . Required during stromule biogenesis in the leaf epidermis, especially in non-mesophyll cells plastids ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRTPCSQHRRDRPSAIGSQLPDADTLDTRQPPLQEIPISSFADKTFTAPAQIRNFCIIAHIDHGKSTLADRMLQLTGVVDERSMRAQYLDRMDIERERGITIKAQNVRLPWRVDKTDYVLHLIDTPGHVDFTYEVSRALEACEGAVLLVDAAQGIEAQTLANLYLALDRDLHIIPVLNKIDLPAADPDRYAAEMAHIIGCEPAEVLRVSGKTGEGVSDLLDEVVRQVPPPQGDAEAPTRAMIFDSVYDIYRGVVTYVRVVDGKISPRERIMMMSTGATHELLEVGIVSPEPKPCEGLGVGEVGYLITGVKDVRQSKVGDTVTSLSRARGAAAEALTGYREPKPMVYSGLYPVDGSDYPNLRDALDKLQLNDAALTYEPETSVALGFGFRCGFLGLLHMEITRERLEREFGLDLISTSPNVVYRVHKDDGTEIRVTNPSDWPEGKIRTVYEPVVKTTIIAPSEFIGTIMELCQSRRGELGGMDYLSPERVELRYTMPLGEIIFDFFDALKSRTRGYASLDYEEAGEQEAALVKVDILLQGEAVDAFSAIVHKDTAYAYGNKMTTKLKELIPRQQFEVPVQAAIGSKIIARENIRAIRKDVLSKCYGGDITRKRKLLEKQKEGKKRMKTIGRVEVPQEAFVAALSTDAAGDKGKK",
    "output": "Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASSRCPAPRGCRCLPGASLAWLGTVLLLLADWVLLRTALPRIFSLLVPTALPLLRVWAVGLSRWAVLWLGACGVLRATVGSKSENAGAQGWLAALKPLAAALGLALPGLALFRELISWGAPGSADSTRLLHWGSHPTAFVVSYAAALPAAALWHKLGSLWVPGGQGGSGNPVRRLLGCLGSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTLMSILTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTEDTSTLSDSLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLITLPLLFLLPKKVGKWYQLLEVQVRESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQKEAVAYAVNSWTTSISGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLLSIYPRVQKAVGSSEKIFEYLDRTPRCPPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQADHILFLEGGAIREGGTHQQLMEKKGCYWAMVQAPADAPE",
    "output": "ABC transporter associated with antigen processing. In complex with TAP2 mediates unidirectional translocation of peptide antigens from cytosol to endoplasmic reticulum (ER) for loading onto MHC class I (MHCI) molecules . Uses the chemical energy of ATP to export peptides against the concentration gradient . During the transport cycle alternates between 'inward-facing' state with peptide binding site facing the cytosol to 'outward-facing' state with peptide binding site facing the ER lumen. Peptide antigen binding to ATP-loaded TAP1-TAP2 induces a switch to hydrolysis-competent 'outward-facing' conformation ready for peptide loading onto nascent MHCI molecules. Subsequently ATP hydrolysis resets the transporter to the 'inward facing' state for a new cycle . Typically transports intracellular peptide antigens of 8 to 13 amino acids that arise from cytosolic proteolysis via IFNG-induced immunoproteasome. Binds peptides with free N- and C-termini, the first three and the C-terminal residues being critical. Preferentially selects peptides having a highly hydrophobic residue at position 3 and hydrophobic or charged residues at the C-terminal anchor. Proline at position 2 has the most destabilizing effect . As a component of the peptide loading complex (PLC), acts as a molecular scaffold essential for peptide-MHCI assembly and antigen presentation ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEKEAGIEVQGTVEEALAGGMYRVKVDQGPTVLAYASGKMKKFHIRIIPGDRVKLELSPYDLTRGRITYRDK",
    "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDVLKITGGIPLKGQVKAAGAKNAMTKLLVASLLSDKKCTFYNVPNIGDVEVTVSLCQEIGMEVRWDRAAGIMEVITKELKTSYIPQRFSGSNRIPILMIGALLGRTDQDIIVPTAGGCPIGQRPVDFHIQALEQLGAVIEYRGMKREGAYFAHAHNGLKGTLITLPYPSVGATENTILAGITARGVTVIKNAAIEPEIVELILFLQKLGAIITIDVDRTIRIQGTRRFYEVEHTVIPDRIEAASWGMAAISSKGKVFVEGAQHLNMITFLNKLREVGGGFDVRSNGIEFFYDGPLQGGLHLETDVHPGFMTDWQQPFVVLLTQSSGTSVVHETVYENRFGYTDTLKEMGADITPFRQCLGGKSCRFASQSFSHSAIIKGATPLVGKEIRIPDLRAGFAYIMAALIANDTSTISGLPFIQRGYENFIGKLADLGANVSLVEEEKNVKEMPENSSKLPLFAELQVN",
    "output": "Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSTAKLVKTKSSDLLYTRNDLDEKVKLAAIKALNHQVVQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTAIIEHQDTFAERVVQLGGVALGTVQVVNDRTPLKSYPTNIHSVQEHLKALADRYGAVANDIRKAITEVEDEDTADMFTAASRDLDKFLWFIESNIE",
    "output": "During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDGDRSKRDSYWSTSPGGSTTKLVSDSERSGKVDTWLLILAFTQWALSIATVIICIVIAARQGYSMERYSMTVEALNTSNKEVKESLTSLIRQEVITRAVNIQSSVQTGIPVLLNKNSRDVIQLIEKSCNRQELTQLCDSTIAVHHAEGIAPLEPHSFWRCPAGEPYLSSDPEVSLLPGPSLLSGSTTISGCVRLPSLSIGEAIYAYSSNLITQGCADIGKSYQVLQLGYISLNSDMFPDLNPVVSHTYDINDNRKSCSVVATGTRGYQLCSMPTVDERTDYSSDGIEDLVLDILDLKGRTKSHRYSNSEIDLDHPFSALYPSVGSGIATEGSLIFLGYGGLTTPLQGDTKCRIQGCQQVSQDTCNEALKITWLGGKQVVSVLIQVNDYLSERPRIRVTTVPITQNYLGAEGRLLKLGDQVYIYTRSSGWHSQLQIGVLDVSHPLTISWTPHEALSRPGNEDCNWYNTCPKECISGVYTDAYPLSPDAANVATVTLYANTSRVNPTIMYSNTTNIINMLRIKDVKLEAAYTTTSCITHFGKGYCFHIIEINQKSLNTLQPMLFKTSIPKLCKAES",
    "output": "Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity).; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGNCLYPVADDNSTKLAIKEDLLIDFPEDYYPDYNETDVEAAAPCHSCSLLNYSSLPFFILVSILGILASGTILYALLRPLFRWQLYQDRSTLVQLAVGSALFSIVVPILARGLSGALITSLCHLAHLVAYGSAFAQALLIGYHACLGPQLGAGQVPGLRLGVTVGLWGVAALLSLPVVLGSDTSQGLCTVTFSGEWETLRYIHAAACFAIFVLLPLGLLGTKGLKTVLGRAPCPWVDVLWVWFIFWWPQGMTLGLDSLVRSKAIVVSTCPAQQALDMLLDVAEALAILHCVATPLLLAWVCYQATHTSPPSLPLPTTQTSHLDTLGSKS",
    "output": "Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNNYETVFILNPVLSDEQIKETVKKYEDFLVSKGAEMVAKEDWGLRKLAYAIQHKKSGFYHLFEYKAPGDAIEPLELEFRREERMMRYLTVKLDKHAIAWAEKRRKRNKEKA",
    "output": "Binds together with S18 to 16S ribosomal RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAQQYQPGQRWISDSEAELGLGTVLAQDGRLLTVLYPATGETRQYALRNAPLTRVRFSPGDVITHFENWKMTVREVDDVDGLLVYHGLNAQNELVTLPETQLSNFIQFRLATDRLFAGQIDQLSWFSLRYNTLEHTSRQLQSSLWGLGGVRAQPIAHQLHIAREVADRIAPRVLLADEVGLGKTIEAGLVIHRQLLSGRASRVLILVPENLQHQWLVEMRRRFNLQVALFDAERFMESDAGNPFEDTQLALVALEWLVEDEKAQDALFAAGWDLMVVDEAHHLVWHEDKASREYSLVEQLAEVIAGVLLLTATPEQLGQDSHFARLRLLDPNRFHDLKAFRAESENYRPVAQAVQELLDKGKLSAAAQETIHGFLGAEGDSLLAAVNTGDEEAKSRLIRELLDRHGTGRVLFRNTRAAVQGFPERKLHQYPLPCPVEYLELPVGEHADLYPEVSFQSHSDVSEEERWWRFDPRVDWLIDTLKMLKRVKVLVICAHAETAMDLEDALRVRSGIPATVFHEGMNILERDRAAAYFADEEFGAQVLICSEIGSEGRNFQFSHHLVLFDLPSHPDLLEQRIGRLDRIGQKHTIELHVPFLETSPQARLFQWYHEALNAFLNTCPTGNALQHQFGPRLLPLLESGDDDKWQTLINEARSERERLESELHTGRDRLLELNSGGAGEGEALVEAILDQDDQFSLPIYMETLFDAFGIDSEDHSENALILKPSEKMLDASFPLGDDEGVTITYDRNQALSREDMQFITWEHPMVQGGMDLVLSGSMGNTAVALIKNKALKPGTVLLELIYVSEVVAPRSLQLGRYLPPAALRCLLDPNGNDLASRVSFNTLNDQLESVPRASANKFIQAQRDQLTPRINAGEEKIMPKHAERVAEAQRRLAADTEEELARLTALQAVNPTVRDSELVALRTQREQGLAMLEKAALRLEAIRVLVAG",
    "output": "Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLDIGTAKASPEEQAAVLHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTGLYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRALEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHSPNVQAAKGIGYKELFPYFRGEQTFEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIGESGVQDRILSQIEEFLDD",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAEPKYKRVLIKLSGEALAGEKGVGIDLPTVQAIAKEIAEVADSGIQIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTTMNALVMADSLKQLGVDTRVQTAIDMKSVAEPYIRGRALRHFEKGRIVIFAAGIGSPYFSTDTTAALRAAEIESDAILMAKNGVDGVYNDDPRKNADAVKFDKLTHVEVIKRGLKIMDATASTLSMDNDIDLVVFNMNEPGNIKRVIFGEQIGTTVSNKAELRK",
    "output": "Catalyzes the reversible phosphorylation of UMP to UDP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVVLGSTGSIGTNSLEIARKFNIEVEALACAENVKKLNAQIAEFHPKFVYIKDEKLKSKVAHNKIFSGENGICEMLNRCESKTVINALVGFAGLIPSLKIQNSGKILCLSNKESLVVGGKFLDTSKIRAIDSEHFGLKFLLENSAKPAKMIITASGGAFYKTPIKDLSSKKAADALKHPNWNMGAKITIDSATMANKLFEMLEAFWLYGCKNLDALIEPSSSVHALIEFIDGSTAAHLSRTDMKLAIAHAILPNLKSEILKPVDLLSLNLKFEKIDIKKYPIFELKDEVLSNPDLGVIINAANEIAVFAFLQGKCGFLDISSTIFKAVEKFNDLTPENAEDLIKIDKIVRNFARSELRL",
    "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRGALAQEATQEHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED",
    "output": "Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "GIDPNYRTSRPEVGTHEGHKVYGPVENPKVLGIHGAIVGVDFDLCIADGSCINA",
    "output": "Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTALSVNDYLRQHIRTVPDWPAPGVQFRDITPLLQNPKVFRVLIDAFVHRYMDRALRPDVVAGLDARGFILGAVVAYELNVGFVPIRKKGKLPFTTVEETYELEYGSATVELHADAVQPGDRVLLIDDLIATGGTMMAGKKLLEKLGATVMEGAAIVDLPELGGSARLRASGLPLYTLVDFSGH",
    "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGKDTIADLLTSIRNADMNKKGTVRVVSTNITENIVKILLREGFIESVRKHQESNRYFLVSTLRHQKRKTRKGIYRTRTFLKRISRPGLRIYANYQGIPKVLGGMGIAILSTSRGIMTDREARLNRIGGEVLCYIW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTEYKKVIAQNKKALFNYFIEERLEAGIVLKGSEVQSLRQGKASIEESHATDTGHEVFLYNCHIAEYEKANRFNHATRRPRKLLLHTKEIKKIIGRIRIKGYTLVALSMYFNKKNKVKVELGIAKGKKLHDKRESIQEKDWKRDQSRLIRQK",
    "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSSDTMFINSARLLPTENRKVKQLQRPDRKKHTRGSYAAQKQQLPNGEQPNFGHGQKQSRKRGSGRQKGRDGAAGDSANVGLTEDLKQLLSIPSGSAGSESAQKETSAGQPATGAVADRKRSVPAGGPAGKSSSEPASASSAVDGMPGLGFQSAHVPFSSPVVNHPMLAEPAATGPVLSVPFPGHVAGYMPCVNNTRVQYPLQTRNNVPMSQPMSQPMSQPMSQPMSQPMSQPISPYLPQGFQMHPQSFVGLPVAPMYPQYMSAQYQSPKQQSACQMPLRAQPPLIPSITRNALPCVSSANSTAKASVRSKGSPGSEGGSRRSQNWKSSQNVGYAGATFATDQPALSSLPKPSFV",
    "output": "mRNA-binding protein which stimulates mRNA decapping."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTAPPVHDRAHHPVRDVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENYPGFRNGITGPELMDEMREQALRFGADLRMEDVESVSLHGPLKSVVTADGQTHRARAVILAMGAAARYLQVPGEQELLGRGVSSCATCDGFFFRDQDIAVIGGGDSAMEEATFLTRFARSVTLVHRRDEFRASKIMLDRARNNDKIRFLTNHTVVAVDGDTTVTGLRVRDTNTGAETTLPVTGVFVAIGHEPRSGLVREAIDVDPDGYVLVQGRTTSTSLPGVFAAGDLVDRTYRQAVTAAGSGCAAAIDAERWLAEHAATGEADSTDALIGAQR",
    "output": "Essential thiol-reducing enzyme that protects the cell from thiol-specific oxidizing stress. Plays a minor role in defense against oxidative and nitrosative stress. Is essential to establish and maintain infection in mice."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MYCYQCEQTAQGVACVTVGLCGKTAEVAALQDLLIEAAKGLSQYAYRLRQLGIALPEIDAFVLDALFTTVTNVSFDPARLEEQLREAACLRDQLRARYDAACAARHTSPETLSGPALWQPASTRAGLVGTGEAASIAHRLTAQGADLTGLQDLLLYGVKGMAAYACHARILGQTDESVAAFVHEVLTTLAEVPADAEALLGLVLRCGTVSLTVLDLLDRANTGAYGDPQPTPVLMGHRAGKAILVSGHDLKDLAVLLEQTVGLGVDIYTHGEMLPAHGYPELKKYPHLVGHYGGAWQRQRSEFAAFPGPILMTTNCIQNPTAAYRDRLFTCGLVAHPEATALSGRNFAPLIASALAAPGFAEDGPVRHHLAGFGHKAVLGVAPQIIDAVKAGAIRRFVLIGGCDGHESARSYFDDLAGSLPQDAVVLTLGCGKFRVIDHDMGTIAGLPRLLDMGQCNDAYSAIKVAQALAEAFGVGVNDLPLSLVLSWFEQKAVTVLLALLALGVRNIRLGPNLPAFITPPVLKVLVDRFGIMPVGTVAEDLAAMGLAA",
    "output": "Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDLLVDDLFADADGVSPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAALFNRLLDDLGFSAGPALCTMLDTWNEDLFSGFPTNADMYRECKFLSTLPSDVIDWGDAHVPERSPIDIRAHGDVAFPTLPATRDELPSYYEAMAQFFRGELRAREESYRTVLANFCSALYRYLRASVRQLHRQAHMRGRNRDLREMLRTTIADRYYRETARLARVLFLHLYLFLSREILWAAYAEQMMRPDLFDGLCCDLESWRQLACLFQPLMFINGSLTVRGVPVEARRLRELNHIREHLNLPLVRSAAAEEPGAPLTTPPVLQGNQARSSGYFMLLIRAKLDSYSSVATSEGESVMREHAYSRGRTRNNYGSTIEGLLDLPDDDDAPAEAGLVAPRMSFLSAGQRPRRLSTTAPITDVSLGDELRLDGEEVDMTPADALDDFDLEMLGDVESPSPGMTHDPVSYGALDVDDFEFEQMFTDAMGIDDFGG",
    "output": "Transcriptional activator of immediate-early (IE) gene products (alpha genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection (By similarity).; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVFCTYCGQSFTRDEHLERHILTHTNVKPFKCFTCHMSFARRDLLQRHYTVHGRDQNQNEIPAVNGMIPKSAGRTPIACSNCAKTKTKCDKKFPCSRCAGRNLRCTLRPTRRASKNANRVGATLESATDVPTEVTTVNVEATSKDTRAQENSSSPSSQKSGTPISIGPIMEETPDIAPPQPFTEQVNGGPTPPEFSPDLQESFMDHNLMSGFPGLTNPSKDSSDDGSSPRFLLDWSQMQMPLGYDNMIQSDLMLDPELSFDPNSVPLAPHADGILSIMPELANGGMESLITPFETPKMSRSFVELGLGNSNPAFHSHRHQSMPSVQSIPNSGNEMPAMIAAQDGWSAFRCTPTLPSSSCPKTAKLNLEQLEETLRNHEGWVSWSPRWEDNDLAGGGDHLTVMQLHESTRDKLLAIMQSFLHKALETHREGRGTSNGSHSPNPSGASNFVLLPPGRVLEYFLRSYSNSFERYFPLTSRSTLDANELMHCYNDRAASILVLLMIAQGAANIPSPEARMLTGGLTEACRISLFDLIERNIIMSGDPIVLHSALLFTVQAAWSGDKWQMDIAMGQRGMYFAMLRHSGVLDRSSHAASAQPQRTLEQLWTDWIQNESRSRLIYSWVMVDQDLALFHDTAPLFSVTEFGAPMPDADRLWHAKSAEQWSSTFERVHEFSSGFSSVGSGARPLSLRDLFRHFLDDDLIPMGIEMTPLQLRLLLHPLQSMVCQFSQLLSCFAPATYRTSISVHPNQAQPSSRNISQSSTRTRLAEVQALLQRWFDLAERYLKANPLCALMQTNLILFHLISLNAVTNFPEIERLARRENVDGTYHQLLWLHKRCIPDVEEAVFHCGQIFRLVRSMPRGVRPPWWAGAIYRVALILWTDSLTHKDALTSTSPQGNGMFPSPIAGPSFAIDALPPDHALIVRYLTKREGVPCVTKLDGSQMGLERAYPVLRHCVEVIDEGCSTRFSDAIRGKLERLSRG",
    "output": "Transcription factor; part of the gene cluster 29 that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment forming a dark layer in the conidial wall that protects the conidia from UV radiations."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTPVASTSALNLARSLYEAGIRNEAVLQAVANTPREQFLDAALGHKAYENTALPIGQGQTISQPYIVAKMTEIILQTKPTKVLEIGTGSGYQAAILARLVPQLFTVERIKSLQIQARQRLKRLDLHNIAFKYGDGWEGWPSKGPYDAIMVTAAASSIPDALVSQLADGGILVIPVGEIAQQLLKVTRSGDKYRSEVVEDVRFVPLINGELA",
    "output": "Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNATTAPLPYSAARLHELAQLLIGNIRELAQAGWTPATSSNFSHRLDEQHAAITVSGRDKGRLVEEDIMVVDFDGQPVGRPLRPSAETLLHTQLYRRFPEIGCVLHTHSPVQTIASRLYAGSGVIRLEGYELLKAFEGNTTHETAVDVPVFANTQDMQVLAAQVEALLDKQSMWGYLIEGHGLYAWGRNMAEARRHLEAFEFLLHCELELLKLRSPR",
    "output": "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEAIKGSDVNVPDAVFAWLLDGRGGVKPLEDNDVIDSQHPCWLHLNYTHPDSARWLASTPLLPNNVRDALAGESSRPRVSRMGEGTLITLRCINGSTDERPDQLVAMRLYMDERFIVSTRQRKVLALDDVVSDLQEGTGPVDCGGWLVDVCDALTDHASEFIEELHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDHRRRMQDIADRLGRGLDEIDACIARTGIMADEIAQVMQESLARRTYTMSLMAMVFLPSTFFTGLFGVNLGGIPGGGWRFGFSLFCILLVVLIGGVTLWLHRSKWL",
    "output": "Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MWQLLSPTALLLLVSVPGTHAEDPPKSVVILDPPWDRLLEKDSVTLKCQGAYPPRDDSTEWRWNGTLISNKASSYSITDATVGNSGEYTCKTGLSAQSDPLRLEVYKGWLLLQAPRWVVQEGESIRLRCHTWKNITIQKVQYFQNGMGKKFSHQNFEYHIPNATLKDGGSYFCRGIIKNYDLSSEPVKVTVQGSKSPSPILSFFLPWHQIIFCLVMGFLFAVDTGLYFSVRKVLRSSKEDWRNGKVTWSRDPADKGG",
    "output": "Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG) . Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC). Does not bind free monomeric IgG, thus avoiding inappropriate effector cell activation in the absence of antigenic trigger (By similarity). Mediates IgG effector functions on natural killer (NK) cells. Binds antigen-IgG complexes generated upon infection and triggers NK cell-dependent cytokine production and degranulation to limit viral load and propagation (By similarity). Fc-binding subunit that associates with FCER1G adapter to form functional signaling complexes. Following the engagement of antigen-IgG complexes, triggers phosphorylation of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapter with subsequent activation of phosphatidylinositol 3-kinase signaling and sustained elevation of intracellular calcium that ultimately drive NK cell activation (By similarity). Mediates enhanced ADCC in response to afucosylated IgGs ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTQLTENTDELHSIRLAIDPNLITLPIGSKSTSPHSNSTSDGNPESHNTENEEVDNKAGSLPPEQFSNNSAKLIVNPYEKYGRMSLGQLIPLISQQRGPNFKFADINEDILKQELAIENDNGKQESKDDTKAEDGIDTMDIDQNDNSEANTNDIGYNEWSNEPKEDTGILDNTQDTNINGEMESQLTQEEFNKIRKVMLEHINMAMNESSLAMEFVSLLLSPVRESTAVSSMSPFLKKTVNPGSLNSEKVKMPAVSRRDKLSLSILSRGWKLRALNEARAILKKNFTEISSSLKQEHHYWSSIAYNISNKDVLFKIRDKQTTKRSLGLKYGYEDSGSTFRNDRGTAILRGTDEANGLELIPLTLGRTSTVGSVYKGGKFLRVRIFTKIESEGDYILSGESSLDKLFKNHSENSDSKNDDVRLQISKLKFFIFEQELMHQLKKECAYLISYGVTVENEHKIVIELPNEKFEIEYLSLDDDSVVNHEQDAPKANDRRANLMLVTLRMLLIVIYKKNLRQKMVSNTRKHIASTEKDILLIRPLLGKMRHSNHKKLIRKILKECVLEVVPDTELQERSIQSLDKEDFETFDLQDAHIVKLTKDINAFRNVLDVGKTEFTIDMKQSGKLSLILESPNYCNAQVSIKYDNQTSNTHFNTVSTEFKEVEEFLHFLISTYVNPE",
    "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADAFSLQRVLETFRSSLSENKEVYIKYYIAGWQELVSFMNSLGNVFSFISKDVVSKIQILENFLSGENGSNYVTIQSMVKYELENDLVDLTKRGSHPESGCRTLLRLHRALRWLELFLERLRTSTEDSKTSVMCSDAYNESLANHHPWLIRKAVGVAFCALPGRETFFDVMNAGDHTQVVALLGESLPLIAEVYQITEDLYAKNNLLELP",
    "output": "Mediates the intracellular transfer of ceramide-1-phosphate (C1P) between organelle membranes and the cell membrane. Required for normal structure of the Golgi stacks. Can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0). Plays a role in the regulation of the cellular levels of ceramide-1-phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid. Has no activity with galactosylceramide, lactosylceramide, sphingomyelin, phosphatidylcholine, phosphatidic acid and ceramide. C1P transfer is stimulated by phosphatidylserine in C1P source vesicles. Regulates autophagy and pyroptosis, but not apoptosis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEGPEIKAVEAVIDNGSFGKRTLRFETGRLAQQADGAVAAYLDDDSMILSTTTAGSSPKENYDFFPLTVDVEEKMYAAGKIPGSFFRREGRPSSEAILACRIIDRPLRPLFPHTLRNEVQVVETVLAVNPDDAYDVIALNAASASTMISGLPFEGPVSGVRLALIDGQWVAFPRWSERERAVFEIVVAGRVIENGDVAIAMIEAGAGKNAWHLIYDEGQTKPDEEVVAGGLEAAKPFIKVICEAQDELKKIAAKETKEFQLFPEYTDELYARIDEIAHKDLDEALSIAEKLPRQDRIHEIKEHVREVLADEFTDMDDAEKDKELGNAFKELQRQIVRRRILTEDYRIDGRGLRDIRTLSAEVDIVPRVHGSALFQRGETQILGVTTLNMLKMEQQIDALSGPQSKRYMHNYEMPPYSTGETGRVGSPKRREIGHGALAEKALVPVLPSREEFPYAIRQVSEAIGSNGSTSMGSVCASTLSLLAAGVPLKAPVAGIAMGLVSGDVDGKHIFKTLTDILGAEDAFGDMDFKVAGTSEFITALQLDTKLDGIPADILAAALQQAKEARATILEVINECIDGPAEMSEFAPRIITTSVPVEKIGEVIGPKGKMINQIQEDTGAEIAIEDDGTVFISSEGGEAAEKAKAIIDQIANPHVPEAGETYNGKVVKTTSFGAFVNLTPGTDGLLHISQIRNLANGERIDAVEDVLKEGDTVEVIVQGVDDRGKISLAIPGFEDQENNARPSRGDRDDRRGGRGRGDRDDRRGGRGRRSERDDRDFDDRDDRPRRRRSDDFEDDYDDRPRRRRSDDRDFDRDDRDDDRPRRRRSADRDFDDRDDRDARDSRDDDRPRRRRSSDRDDRGDRDDRRGGSRGRGRGSDRNPRYATDDNYDDYRADREERTERPRRRVRRDFDPFED",
    "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKDLTNYRNFGIFAHVDAGKTTTTERILKLTGKIHKIGEVHEGAATTDFMEQEQERGITIQSAATSCFWKDHQLNIIDTPGHVDFTIEVYRSLKVLDGGVGVFCGSGGVEPQSETNWRYANDSKVARIIYVNKLDRTGADFYKVVKQVKDVLAAEPLVMVLPIGIENDFVGVVDLLTRKAWVWDDSGDPTKYEIKDVPENMTDDVEKYREMLVETAIEQDDEVMEKYLEGEEPDLDTLKRCIRKGTKDLVFFPTYCGSSFKNKGVQLVLDAVVDFLPNPTEIKPQPEIDLEGNETGKFAYVDPEKPLRALAFKIMDDKYGALTFTRIYSGTLSKGDTVLNTFTGKTERIGRLVEMHADSREEIESAQAGDIVAIVGMKNVQTGHTLCDPKEPATLEPMVFPDPVISIAVAAKDKGSVEKLGMALSKMVQEDPSFRVETDAESNETIIKGMGELHLDIKVDILKRTYGVDVEVGKPQVAYRESITKRLEDSYTHKKQSGGSGQFAKIDYMIEPGEVGTGFDFQSKVTGGNVPREFWPAVQKGFETSFEKGMLAGYPCVDMKFTLMDGAFHPVDSSAIAFEIAAKAAYRQSFSKAAPQLLEPIMKVDVFTPDDHVGDVIGDLNRRRGMIKSQDSAATGSRIKADVPLSEMFGYIGDLRTMTSGRGQFSMEFSHYAPCPANVAEVVIKEAKERQEAKSK",
    "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKTAQELRAGNVFMVGSDPMVVQKAEFSKSGRNASVVKMKMKNLLTGAGSEAVYRADDKFDVVVLDRKDCTYSYFADPMYVFMDTEFNQYEVEADNLGDTINYIVDGMEDVCQVTFYDGKAISVELPTTVIREVEYTEPAVRGDTSGKVLKPARLVGTTFEVQVPAFVNTGEKIEIDTRTNEFKKRA",
    "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFGFLIGVFFDRREESKCEPLVKHAPAIEPEASEAENYPLSSSADDKILAEALDAVETTILGSGSCLHVTDTAAMPPAGDSAAAAVMMGSHSPGDRLMIEALESVEASRGLTHSADTCSQRCSIALSAPQSPQSRVPEGPIMDSGQIFAVSGAGEEENWIDDEDMALCAADLQIDPIGDAQSVGGSTAACLPPSQKEEIRILYATDGYPVVCSLHLLLGQALLQELYVIAYSHVTEPSAHGGGLLRATFYLLAATGCERQRQRVRPVFVCSFTGEAADKTREALREGKPLMVQDVIASLDEAQSLALHEDLIIALGTICSAGKTAAAPGGDERNLSYNYVASTLPGLRRTLASLMLQYETRVVAAFRRKYNASFSCPFWFVSKFGPSETSLVAVLRYYLLGATQDDGIAGSFDLQGVKDLAVTFPKPGANASGLTAARLNTFAEFSRFWCCSELAGPKAEKLFREYLKTRVSSDTLYVQSLDSLIEKYRHALRLPAKDFVRFVYLAYHEGYNRAAVEAHMEEALRNGGRAETAATRAQSEFFKGLREMCSMPEYFARNVDVAVKRLPVRVAEEHARLRSYGEIPRSGFWGFCWPSYDVSLRINKICAGPLCCLGTQLADAMVRAPPDDGDKGTCAETAATIIHHDSDASGEEEATVKVCGAHMPRANKRAGDGTRISPACNEADTRAPLARLTALAYSDQRPRGIMPVTLLLYSLDDTSSGADTAVKSEAKAQDRPVPVYRVAMPGGGQAFAVVARDQWDKTVTVDVFSGFMAPKSPPESNGPLGSDKDAAAVDDAWTRALLARAWGTSYARRCAANVGASQLYLNRNEVLSDSLAVCNLPLDLDITLKPSSVGRPSMLTLHMAMRSVREAIVLLWSLLFADAEIDPDTYPVYFYKTQCDAAAGDEEASPQRRGVGGGDDDVAWGEEDVEIEEMWGGYYSQTAMNDDMIWDDAPDPQMDIDSDHPAHEPMDDGAGAAIEEMKTAAAARFCRCERKIGFRICVPIPKPYALAGLSVAKATSALVQQAIVLQEKFVEALDQFIADYEFVDSGVYSAGRSLRLPFFAKVNARGVMVGRLLPFLVFPPKCRDRSEFVAQHADPNNFHVGAARRDNPAPTLIITSVTVRRDVLAQDNRAHGKPRAGTARLADALAAVGIVPGNQQGTPGDACAVDASWLLDSVAMPALREYIDEHFPRHAAEYRDARTDCIRVYEGRICAALRRGGAGYMSGRRSNFTCLKYQHRGASMQTVIASVVVAVNSQGLPYAALQTRCFATKCGSNELQTQFTVTLSATKDV",
    "output": "Essential component of the helicase/primase complex. Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis. The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLSTPVTSQLRLKEFQDVYEPAEDTFALLDALEKDAKKLRQMAEMKNLLTAEIGCGSGCASSFLKSGILKNKPIVHFMSDISNSACRASKITALNNRELYKDDNGLFITVQTSFLDGIRLGNGVDILIFNPPYVPTEFEEIPSEAATIASAWAGGTDGMDVTSTLLNQLKDILSQDGVFYMVAVARNKLHSICEILQKDGFIVNETLKRKAGRETLSILRIYRIGNTIWDE",
    "output": "Methylates eRF1 on 'Gln-182' using S-adenosyl L-methionine as methyl donor. eRF1 needs to be complexed to eRF3 in its GTP-bound form to be efficiently methylated."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTKSELIERLAGQQSHISAKTVEDAVKEILDHMAITLADGERIEVRGFGSFSLHYRAPRVGRNPKTGDKVELEGKYVPHFKPGKELRDRVNIYD",
    "output": "This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLVLTRKMGEVVTIGDSIRIKVVEMKGNQVRLGIEAPNDMRIYREEIYIKVQRENQIAASWSLADLEKAVTCLGADGKE",
    "output": "A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNDSLSRLPREPADRLTKPFMRFLRIEATAGIILLLSTLLALGLANTAWSSSFLAFWEMPAGVRLGDIGIYRSLKHWINDGLMTFFFFVIALELKRELVLGELRNPRMAALPVAAALGGMAAPAGIYLLLVGGGPGASGWGTVMSTDTAFVIGCLALLGSRVPGSLRLFLLSLAIFDDIGAILIVAVGYGEPLNWVALGTGGLGFAFVAGIALLGIRSIPVYFAMGSAIWLAFDASGVHATLVGVILGLMTPARRWVSEIRLHAILDRVIAHPPGDHRSRDTAARSDLHRAGVATREAVSPIERLEIALHPWVAFAIMPLFAVSNAGIPIEDANFDVPLTIAIVVAFVVGKPAGIVLFSFLAVKLRLASRPEQLSWSLLAAGSLLTGIGFTMALFIAELAFEPELLIPVKLGVLGASVISAALGFMALTLLTSPNRR",
    "output": "Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEHLPMAFNTTNPLIQVEDDRTGLSVETLKRALADNLFYLQGKFPAIATKNDCYMALAYTIRDRLLQRWLNTFQTYLNCDNRVVCYLSAEYLLGPHLGNNLINLGLWEPVQQAVEESGLSLDELIDIEEEPGLGNGGLGRLAACFMDSLATLEIPAIGYGIRYEFGIFDQEIKDGWQVEITDKWLQLGNPWEIARPESAVLVKLGGHTEPYTDDQGNYRVRWIAGSLVKGIPYDTPILGYKVSTANNLRLWKSEAAESFDFQRFNVGDYYGAVQDKMSSENLTKVLYPNDEQIQGKELRLAQQYFFVSCSLQDMIRIHLSDNPTLENFHEHFAVQMNDTHPSIAVAELMRLLVDEHHYEWQRAWAITEATFGFTNHTLLPEALEKWSLPLFGEMLPRHLEIIYEINQRFLDQVRMKYPNDGDRLARLSIIDEAGEKSVRMAYLATVGSHAINGVAALHSQLVKETILKDFYELWPEKFSNKTNGVTPRRWMVLSNPRLSNLISSRIGDGWIKNLDELKQLEPFADLAGFRQDWCKVKREVKQDLARYIHTRTDLVVNPDSLFDVQVKRIHEYKRQHLNILHVIHLYLQIKNNPNLDVTPRTFIYGGKAAPGYFTAKLIIKLINSVADVVNNDPTIGDRLKVIFLPDYNVKFGQRVYPAADLSEQISTAGKEASGTGNMKFSMNGALTIGTLDGANIEIREEVGAENFFLFGLTTPEVEKTLAEGYQPWEYYNNNANLKAVVDLINSGFFSHGDTALFRPLMDSLLGQDPYLVFADFQAYVDCQNQVGEAYKDQENWARMAILNVARMGKFSSDRTIREYAEDIWAIKPVVIELEDLCPDGQCLLISPNK",
    "output": "Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGKFVVLDHPLIQHKLTIIRRKDTGSNEFRRIVGEIGGLMTYEITRDLPLKDVEIETPMGKTVQKEIAGKKLTIVPILRAGIGMLNGVLDMVPSAKIAVIGMYRDEKTLKPHEYFFKAPKDIAERDCLVVDPMLATGGSANDAIAALKKRGVKEINLAVLVAAPEGIKAVQEANPDVDIYAAAEDEKLMDNGYIFPGLGDAGDRLFGTK",
    "output": "Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGKESGWDSGRAAVAAVVGGVVAVGTVLVALSAMGFTSVGIAASSIAAKMMSTAAIANGGGVAAGSLVAILQSVGAAGLSVTSKVIGGFAGTALGAWLGSPPSS",
    "output": "Plays a role in the apoptotic process and has a pro-apoptotic activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVHVVTCTLGEEGEVIGDRWAQLTADHADQLGGYRIGELTAALRALGVSAPIYLGGAGRWRDSGMAGTDQRSQRRFVDADPRQTVGALVAIIRELRPHVVVTYDPNGGYGHPDHVHTHTVTTAAVAAAGVGSGTADHPGDPWTVPKFYWTVLGLSALISGARALVPDDLRPEWVLPRADEIAFGYSDDGIDAVVEADEQARAAKVAALAAHATQVVVGPTGRAAALSNNLALPILADEHYVLAGGSAGARDERGWETDLLAGLGFTASGT",
    "output": "Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFRQWSVQSGPAPRRPESQAASEELWEQEVERLCASRTPVRMLPYAMADKRFIRELREPEGVKTTFWQRWHRPRRVARQHLREAEQRLARGFGLWEGALYEIGGLFGTGIQSYFTFLRFLLLLNLLTMLLTACFVLLPLVWLRPPELGPALKLRLQCSSSPLPQSDIPRFHNPLWNILTGRAFNNTYLFYGAYRAGPESSSEYSIRLAYLLSPMVCLLLCFCGILQRMAEGLPQQTLLGQRYRTPLSAKVFSSWDFCIRVWEAATIKKHEISNELKMELEEGRRVELAQQQTRAQKACRLLTYLRTNILIVLLVVGAISAIFWATKYSQDNKEESLFLVLQYLPPGVISLVNFLGPQLFTVLIQLENYPPGTEVNLTLIWCVVLKLASLGMFSFSLGQTVLCIGRNKTSCESYGYNACDYQCWENSVGEELYKLIIFNFLLTVAFAFLVSLPRRLLVERFSGWFWTWLDREEFLVPKNVLDIVAAQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLRNSRASPRRFRASSSTFFFHLVLLLGLLLAAVPLAYVISSTHSSWDCGLFTNYSAPWQVVPELVALQLPLPSQRALRYLSSHAFSFPLLILLSIVLTVCISQSRANARAIQGLRKQLVWQVQEKWHLVDDLSRLLPELSPEPGSPHSRASRPRSFCPGFPCPGSPGPRTPRLAPSNRLSSSSLGAPSASVPASRFHFPSRTEL",
    "output": "Probable ion channel."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDKFRRNGKEDTFRQRRFLYPLLFQENLYAIAYDHYLSRSSSFESMENSSYNDRFSFLTVKRLISRIRQQNGSIVSFGNYNQNKNKLVGHNRNFYSELVLEGLTVVLEVTFSIQSKHYLEGMNEWNSFRSIHSIFPFMEDKFPHSNFLLDIRIPHSTHPEILVRTFRYWIQDAPSLHSLRSVLHEHRNLILSENLDQLILIASKEKTRLSLSVLWNYYVYECESLLVPLWKRFSYSRSLSYGAFLERTTFYRKIEHIVIFSHKSIKDLKKRIWFLKDPSIHYVKDRERFLIALRGTYLLVKKWRYHLTNFWQCHFHLRSQPYRMSIDELSKNCFSFLGYLFSVQMKTFVVKIKMLDDSFITDPITKEFDPIAPTTLLIGYLAKERFCDISGRPTGRLAWTGLTDDNILHRFDRIWRNILHYYSGSSKKDGLYRMKYILRLPCAKTLACKHKSAIRVVRERFGSELFTKSSPKERELISLSFSKTRSQRERIWHSDILQRNPFVNSWWNKQNLQVETPFDR",
    "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAPSEAPERRRPFGRRFLTDPTRLFQHNAWDNVEWSEEQEATAKSKVQENSSQLLPQDKQEEYEVNAKRYWDDFYKIHENGFFKDRHWLFTEFPELAPNRNPSQNEDSLCEFSCKEVSKNEGLGSCENGHCTLENRAENQLNLLKSSPRFCTEELAPQKLKQSYEDYPGSSASYRILEVGCGAGNTVFPILQTNNDPGLFVYCCDFSTTAVDLVQSNVEYDSSRCFAFVHDLCNDQSPFPMPDESLDIVILIFVLSAILPEKMQCVINKLSRLLKPGGMILLRDYGRYDLAQLRFKKGQCLSANFYVRGDGTRVYFFTQDELDDLFTRAGLQKIQNLVDRRLQVNRGKQMTMYRVWIQCKYQKPAGPQL",
    "output": "S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). N(3)-methylcytidine methylation by METTL2 requires the N6-threonylcarbamoylation of tRNA (t6A37) by the EKC/KEOPS complex as prerequisite."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLELRLVQGSLLKKVLESIKDLVNDANFDCSATGFSLQAMDSSHVALVALLLRSEGFEHYRCDRNISMGMNLANMAKMLKCAGNDDIITLKADDGSDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPEAEYHAIVRMPSAEFSRICKDLSSIGDTVVISVTKEGVKFSTRGDIGTANIVCRQNTTVDKPEEATVIEMNEPVSLTFALRYLNSFTKATPLSNTVTISLSSELPVVVEYKIAEMGYIRFYLAPKIEEDEEETKP",
    "output": "This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSLSDKDKSAVKALWSKINKSADVIGNDAVSRMIVVYPQTKTYFAHWPDLTPGSTHIKAHGKKVMGGIALAVSKIDDLKAGLSNLSEQHAFKLRVDPANFKILNHCIMVVISSMFPKDFTPEAHVSLDKFLSAVALALAEKYR",
    "output": "Involved in oxygen transport from gills to the various peripheral tissues."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGRSISVSFGLLVVFLSLSGTGADQDCLPGWSFYEGHCYKVFNVKKTWEDAEKFCQKQSNGKHLATIEWLGKANFVAELVTLMKLETHVWIGLRVEDKRQQCSSHWTDGSAVSYENVVHNTKCFGLDQKTGYRTWVALRCELAYHFICMSRVPRGA",
    "output": "Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLKGGMLSRWKMWSPQYKILRNHLINFKSVSTYKNISGVNTKQPKSPRQFGCMPHVTKKRKYKYEEGKTYHGFQCERVEHISEFELTSYTFRYERTGTELWHIDRNDSNNVFSINFRTTPFDSTGLPHILEHLSLCGSQKYPVRDPFFKMLNRSVATFMNAMTGPDYTIYPFSTMNEIDFRNLQHIYLDAVFRPNLAYFDFLQEGWRLENKDIFDKQSKLVIKGVVYNEMKGAFSENAQVFSQNLLNNIFPDHTYRHVSGGNPLEIPKLAYNDLVEFHKKYYHPSNARIYSYGLFDASKTLALLDEEYLSDQSWVDNSYSLIRQQERWTQPRLVHISSRLDNMGTTIDRQNQIAIALLMCDATNIQESFELHVLSEVLIRGPNSPFYKNLIEPNFSGGYNQTTGYSSDTKDTTFVVGLQDLRVEDFKKCIEIFDKTIINSMNDGFDSQHVESVLHNLELSLKHQNPNFGNTLLFNSTALWNHDGDVVSNLRVSDMISGLRESISQNKKYFQEKIEKYFANNNHRLTLTMSPDEAYEDKFKQAELELVEQKVKLLDEVKIEKIYERGLILDSYQKAESNTDLLPCLTMNDVRDPPKWPKLFIQNVQNVRTQICKVPTNEITYFKCMFNITGLSHEETQLMPLFCNVISAMGTTNYNYREFDKHILLKTGGFDFKLHLIEDVRDSKSYSLSVMINTHALNNNVPEMFALCQELIKNVRFDDSERLKMLIENYISYISVGVASSGHLYAMLGATSQVCDAGKLKSLLYGVDHIDFMKNFVHSTSTVDICDKLSTIASKVFNKDNMRGAINTTQSYEPSAISNYEKFLESLPTFGKTQTSRNIHYLDPSCQQYVMNIPVNYCAKALFTVPYLHQDHPTLRVLAKLLSAKYLLPVIREKNGAYGAGAKISSDGIFSFYSYRDPNSTKTLNAFDETYKWLRANQNVIDQQSLFESKLGVLQQLDTPIAPGNIGIDYFLYEVSQEDFESYRSRMLSVTIDDLQCAIENYFGKESMHYGKCILGPVNANLELETSHKWIINN",
    "output": "ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFLLNSLSRITRGNRSKRHQNLSDASSSSGSFSKKSSTSQLVRTGSPSVEPTALYLQQPFVRTHLVKGNFSTIVSLPRFVDLDEWVALNVYELFTYLNHFYDVFATFCTVKTCPVMSAAANFDYTWLDNNRKPVHLPAPQYIEYVLAWIENRLHDQNVFPTKAGLPFPSNFLVIVKAIYKQMFRIFAHMYYAHYAEILHLSLEAHWNSFFAHFIAFGKEFQLLDKRDTAPLKDLIVVLENQGNI",
    "output": "Required for coordinating polarized cell growth during interphase with the onset of mitosis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "GTPCKCHGYIGVYWFMLAGCPNGYGYNLSCPYFLGICCVKK",
    "output": "Weakly and reversibly inhibits rat homomeric ASIC1 (isoform ASIC1a) (IC(50)=4.8 uM), and ASIC3 (IC(50)=15.9 uM) . In vivo, induces an antihyperalgesic effect in the acid-induced muscle pain mice model . Molecular modeling interaction with ASIC1a suggests that this peptide hinders the collapse of acidic pockets and stabilizes nonconducting channels state ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRIDILTLFPEMFAPLEHSIVGKARDKGLLEINYHNFRENAEKARHVDDEPYGGGQGMLLLAQPIFDTMDSIEQTKPRVILLDPAGRTFNQAYAEELAQEEQLIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKEVSHTDDSFSSGLLEYPQYTRPYEYRGMVVPDVLMSGHHENIRKWRLEESLRKTYQRRPDLLENYNFTAEELTIFEKIKAEDTVD",
    "output": "Specifically methylates guanosine-37 in various tRNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKAQRMRIKLKSFDYKLLDQSARKIVETAKSTGAEVSGPVPLPTDREVITIIRAPHKYKDSREQFEIKTHKRLIDIIKPTQKTVDALMRVELPAGVDIEIKLKEV",
    "output": "Involved in the binding of tRNA to the ribosomes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARSIWKGPFVDGYLIKKVQKLMESGKSEMIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNEEMVGRKLGEFAPTRTFHGHGADKKIKRK",
    "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGRGKIEIKRIENSTNRQVTFSKRRAGILKKAREIGVLCDAEVGVVIFSSAGKLSDYCTPKTTSVFPPLSRILEKYQTNSGKILWDEKHKSLSAEIDRVKKENDNMQIELRHMKGEDLNSLQPKELIAIEEALNNGQANLRDKMMDHWRMHKRNEKMLEDEHKMLAFRVHQQEVELSGGIRELELGYHHDDRDFAASMPFTFRVQPSHPNLQQEK",
    "output": "Probable transcription factor involved in the development of floral organs. B-class protein required for normal development of lodicules and stamens (whorls 2 and 3). May function as a heterodimer with MADS16."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKICLIDETGTGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV",
    "output": "Specifically methylates the guanosine in position 1516 of 16S rRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSTAKLVKSKATNLLYTRNDVSDSEKKATVELLNRQVIQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKTPLKSYPLDIHNVQDHLKELADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLWFIESNIE",
    "output": "During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects the cell from UV and gamma irradiation, iron and copper toxicity, thermal stress and acid and base shocks. Also shows a weak catalase activity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQQLIAEITKGQLKTDLPSFRPGDTLRVHVKVVEGTRERIQLFEGVVIKRRGGGISETFTVRKISYGVGVERTFPVHTPRIAKIEVLRRGKVRRAKLYYLRNLRGKKARIKEIR",
    "output": "This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKLLSRNDARKAKHLRIRNKIRKTTNLPRVFVYKSLQNFYAQLFDDKLNKTIVSLGTSKNKEYSGNIAAAKKLGHEMGALLKTKKIDKIVFDRSGYIYHGRVKAFAEAMREEGVKF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAITDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDSLNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELTIPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKKKETPNKYPRKAGMPNKRPL",
    "output": "Specifically methylates the N7 position of a guanine in 16S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDLDIKEIVKNMDLKFRNIEGKKLLLAISTDKSGKVLMTAFMSEESLEKSIETGFMHYYSTSRDKLWRKGEESGNVQKIINVFRDCDGDALLFTVEQTGWACHEGYMSCFHNKIDLSTGKSTVVGNKLD",
    "output": "Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADASNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKMDGRQMFMQLAPISDKK",
    "output": "IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MHLFTYDLHHDVGGAENMLRLPLDRHERDYLPWERHIHALVVLLVKQGRMSVDELRRGVEGLPSSLAEQASYYEKWGLSVSRILTEKGTVSGHELEQGFLGVPTTDLPQVPRFQVGQRVMVRPFGTTFAYRQPHLRVPGYVHGAVGTIVELPGLFQDPMTGAYGERGTAQPLYRVAFSHRALWPEGAAHAEPGELEDGVVVDVSQPWLEALSEADYAQRLATLHRVAFTPDSNPPQAHKHHHHRHHHDHHHHHHHHHAMHAEHEAHTHDTRYGTEQAAVAKEAALDFPYQPWCEALVQTLTRRGVVRSDELHATLASLDALQNSGAGPQLVARAWSDAAFAEWLLTDAAAAAESLAIRTTNYDADPASAERVGGHRLFSHNHTELRVVANTDTVHNLVCCTLCSCYPTAILGLSPPWYKSKVFRARAVREPRRLLREEFGLVLPEARGIRVHDSTADLRYMVLPQRPQGTEGWSEEHLRTIVTRDSLLGTAVPRVD",
    "output": "NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQVPSPSAREAASMYGTAVAVFLVLLVAVLQGLAPPESPLPYRIPLDPKGDLELSWDVSYTQKTIYFQLLVQELKAGVLFGMSDRGELENADLVVLWTDGDNAYFGDAWSDQRGQIHLDSQQDYQLLRAQRTPKGLCLLFKRPFGTCDPKDYFIEDGTVHLVYGVLEEPFGSLEAINTSGLQKGLQRVQLLKPKISIPALPEDRRTMDIQAHNVLIPSKTTYWCHLTKLPQDFPRHHIVMYEPIITKGNEALVHHIEIFQCTNQFQNITSFSGSCDSKEKPQELKVCRHVLAAWALGARAFYYPEEAGLAFGGSNSSRFLLLEIHYHNPTNIRGRYDNSGIRLHYTAKLRHFNAGIMELGLVYTPVMAIPPKESAFVLTGYCTAKCTQAALPPLGIRIFASQLHTHLTGTKVVTMLVRDGQEIEIVNRDDHYSPNFQEIRMLKKTVYVYPGDVLITSCTYNTEDKNEATVGGLGTQEEMCVNYIHYYPQTQLELCKSHIDPCFLQKYFHLVNRSNLGEYCTCPQASGTTCPQASGTTCPRASVPEQFASVPWNSFSRVVLKALYDFIPVTVHCNKSSAVRFPGKWDLQPLPEIISKLKEPTPRCPTSRDQSSSSLTVVNIGGGKV",
    "output": "Conversion of dopamine to noradrenaline."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MERSALQWVGAPCGSHGPYVFYRAFRFQRRGGGRARVLSLGDFFFVRCRAEEPACIAELQLLWEERTSRQLLSSAKLYFLPEDTPQGRTSDHGEDEVIAVSEKVTVKLEDLAKWAQSDFSKWKCGFRAEPVKPMDVGKNGQKEALMRYRQSTLNSGLNFKDILKEKADLGEDDEDSNLLILSYPQYCRYRSMLKRIQDKPSSILTDQFVLALGGIAVTSKNPQIFYCRDTFDHPTLIENESICDEFAPNLKGRPRKKKPCPQRRDSLNGIKDSNNNSESKAVAKVKCEAKSALPKPKSNNSNCKKGSSEDKSKIAVGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPVKPRKQDNSSQEGEAKTKVSGTKRIKNENQKSKKEKDNAQKPQDASEVSSEQEKDQESADQKNFTEHPTAGETKQPNQGPPPLLPEAARPLPMEKIDVTENSSSSEKAKEEVPHLSSFPSLSMPPDEDTVLDATVTKRLHSSADTQEDTKPERRIHKAFTESLENEPPEMPFSTFPVQLPTQSDMEDDKLPEMADYIANCTVKVDQLGNEDIHNALKQTPKVLVVQNFDMFKEKELPGSMSDDSTFGYTPLLYSKGNPGIMSPLAKKKLLSQVSGAALSCSYPYGSPPPLISKKKLNSRDELSSSLSQGPHVPNSDPIAINRPSVIQHVQSFKSKEERKSINDVFKHDMLSKVDPQRCDFSQHCLSSLAESYVPKTDIQDCKDKMTEKRALQHSRVPTFLADFYSSPHLHNLFRHTEHHLNNEQTSKYLPRDMFRESENISTFTQHKHQEKLNLNYHPSLHQQEKKATVEASSDDQPTDLSLPKSIHKQTAKAPGPGLSHSSMAQQEGKGVSLFQAASSQAVSLDCNPKACRVSPMAMTAPKKHSELLHRSGKQQAQRLENLRKMEGMVHPIISRRMSPQNIGAARPLKRGLEELDKVISEKKVRAVSPLHLPKETSVKEKVPDAEGEGSKSLHGLHSGSVLESHKFPLSAPIFPGLYPGTLCTGLNNRLPPGYSHPLQYLKNQTVLSPLMQPLALHSLMVQRQFLTSPANSQQLYRHLATATPVGSSYGDLLHNSIYPLAAINPQAAFPPSQLSSVHPSTKL",
    "output": "Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPLTNTFKLGPGVDVNYMLHTQNK",
    "output": "O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKKIGLFYGTQTGKTESVAEIIRDEFGNDVVTLHDVSQAEVTDLNDYQYLIIGCPTWNIGELQSDWEGLYSELDDVDFNGKLVAYFGTGDQIGYADNFQDAIGILEEKISQRGGKTVGYWSTDGYDFNDSKALRNGKFVGLALDEDNQSDLTDDRIKSWVAQLKSEFGL",
    "output": "Low-potential electron donor to a number of redox enzymes."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSRLTKQQILEQLKNGLIASCQPVDDGPMDSPEIVAAMAKASVIGGAAGLRIEGIDNLKAVRKVVDVPIVGIVKRDLPDSPVRITPFLQDIDDLYHAGADIIAFDGTDRVRPTTIEACARRIQELGAMSMADCSNYKEGMYCQELGVDLIGSTMSGYTGGETPDEPDVQLVRDLVASGCRVMAEGRYNTPELAAVAIENGAYAVTVGSALTRLEHIVSWFVTAIDDRKTGA",
    "output": "Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLAKRIIPCLDVTGGRVVKGVNFVELRDAGDPVEIAARYNAQGADELTFLDITATSDGRDLILPIIESVASQVFIPLTVGGGVRTVEDVRRLLNAGADKTSFNSAAIANPEVINAASDKYGAQCIVVAIDAKRRTAEDEQRMGADGRAAGPGWDVYSHGGRKNTGLDAVQWAAEMARRGAGEILLTSMDRDGTKSGFDLKLTRAVSDAVPVPVIASGGVGSLDDLADGVTLGGADAVLAASIFHYGEFTVGQAKQRMAERGVPVRL",
    "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGDEKLSRHTSLKRARSLSESIKGLFKPSGISGSNNAAAPSSRPGQDQAHSHQTARIITSNVSSPSISPVHSPVLQAAPKHHKLGVPNIAKLSLSPSREPSLNSENEMFSQESFISEKDEDEANLLEREDLQNKKEEKARAKHVRSKEAYVPHHRYTGGSDEVERQPRERLKNFPQNAGSSNPANSNANHVLDQENNFSIDAMLDYDEESKLRRRNSLGVRNHSNRTRSRKNSLSTPRSPPMKNGNDGMNSNATNNVGNGTGNRIYMRGRNQSDSISASSLPKFQEIECKCILDLGHFKVFENGYHEHSLRVLPIITNNKNVDSGDEKDADASVNSGDDGDNDSEANMHKQKSVFSLSGLFKSHKDGNQQQQQQQQQEENGEQINLEKAFSIIPSQRFIKSQTVKKSRTSNLKNGNNDELMKNDGKNIPQIVNPNAAVGAEELKLINALSEKIRKGLKSENTKGNNGEGRSNSNKQEDSDDTEGKAGTTNDDTSHKPCSQKYGKYIGVVGAGAYGVVKICARCKTAKDVLPYSTYSNGKKLFFAVKELKPKPGDQIDKFCTRLTSEFIIGHSLSHPHFEANAMIAGNVSRTTPPKHVFNAPNILKILDLMEYSNSFVEVMEFCASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLWKIAIPEKDSLFKSFLSEIKDDGQFYLFEELRHVSSELNRLRKIALYRTFQVDPTKRITIEQLLQSSWMRKTKCCVVYRPLHTKVSK",
    "output": "Protein kinase involved in salt tolerance and pH sensitivity, probably by regulating plasma membrane potential and cation influx. Positively controls the TRK1-TRK2 potassium transport system in response to potassium starvation. Stabilizes TRK1 in the plasma membrane by preventing its vacuolar sorting and degradation. Also stabilizes other plasma membrane nutrient transporters like CAN1, FUR4 and HXT1. May itself be subject to regulation by ARL1 (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSMANLLLLIVPILIAMAFLMLTERKILGYMQLRKGPNVVGPYGLLQPFADAMKLFTKEPLKPSTSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSGWASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMNGSFNLSTLIMTQEHLWLLLPTWPLAMMWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPLALFFMAEYMNIIMMNTLTTMIFLGTTYNAHSPELYTVCFITKTLLLTSLFLWIRTAYPRFRYDQLMHLLWKNFLPLTLALLMWYISMPTTISSIPPQT",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNTYFRFEWINGEENPCEYNLWRMFQIEPKPKSGANFMKPNLPNTENFSTASSSKIRQLSEQPSCSNSYKKLRHEMGSDNSNIDDPLDDYDDRKKKLAKKKAAFKAKKGYTTGQNKSDNSFEFEVEKSMDRKEPENGDEEESTEDDYRHAYSSVEKSLRKISLLPIQRPSHHTFCVFCSESYPPVEFHFCIFMTAAQKEVNQSVNEFLGKADTINKKMLESLKKFIHTSKVDTIAKHSRMENTSMKKNSDSPKKLKRPSTDPNPISKRFRHISDESTSSSSLAKNKSRSVTPDALPFAMIDSQEHRTQSGRVVKRPNLFCHKEVQIRKETVQKEGLKKKRVNKEKEVEQESTILLGISESERKRNRNMIRRLLANGFELPGDDYVLPPLPADKSTWTREQHKMDIYGPIYCALQSFKPAYTTDMTSEFLEDDGDTEFKSENSESDSDSEDEQKVENDVASSADDIEFIEIVEAERKMDQNLAQQVRSSFVTTAENTENNMLMEDDSSEQGSSKFNRNASRRSTENIEFITIDDDDDDDNDIEIIA",
    "output": "May play a role in transgenerational epigenetic inheritance."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGVELAFPKVVGKQVYGSLYDCDENVLKDTKRLEQIIKEAADVGNMNILDIKSWKIGEGVSVVAIILESHITIHTWPEYKFATVDVYSCGPHTSPLKAFNYIVEKLGAKKYTINEADRSSEF",
    "output": "Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MYGRSGLDRFKKSQTSEPFSVSANPPPVVQQHLSPEALSGQKTQIGAGQSNWHPPDWAIEPRAGVYSLEVVKDGQILDRIHLDRRRHIFGRQHQTCDFVLDHQSVSRQHAAVVPHKNGSIFVIDLGSAHGTFVANERLTKDTPVELEVGQSLRFAASTRIYLLRKNSEALFSRPPPPAEIKLPPPPDASDEEAVVAYNTLLNRYGLSNGESGGMLGKRKEKTGSEAGVAKRMKKVRVSFRDQLGGELAEIVGMSDGADVETEPGPINVKEGSLVGKYESLVRVTLIPKGKVKEEKAFTGGTRGGVTDRLQEAMNMLKRGPKTGIYDDLYGGDSLAKAVGTSWASVSQPAAETECGGVGEEDDNDDLFGD",
    "output": "Inhibitor of protein-phosphatase 1 (PP1). Binds to and inhibits PP1 activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSPSVALAVLALLSLSGLEAIQRTPKIQVYSRHPPENGKPNFLNCYVSGFHPSDIEVDLLKNGEKMGKVEHSDLSFSKDWSFYLLYYTEFTPNEKDEYACRVNHVTLSGPRTVKWDRDM",
    "output": "Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKPARRVAVTGAAGQIAYSLLFRIARGDLLGDDQPVILQLLELPHALDALRGVVMELEDCAFPLLQSVEISDDPRVAFRDADYAMLVGSRPRGKGMERRDLLAANAAIFRSQGEALNEVANRQVKVLVVGNPANTNAWVARHYAPDLPADAITAMIRLDHNRAVSKLAARCGVTVDAVSRMAVWGNHSPTMFPDYRHALIDQQPAPMRVGDERWYLDTFIPEVARRGTAIIEARGASSAASAANAAIDQMRDWIRGSGGRWVSMSIVSGGEYGIPRGLMFGMPTICSEGRYRVVPDLEIDALARARIDASVAELVDEMQAVRAILAL",
    "output": "Catalyzes the reversible oxidation of malate to oxaloacetate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSTMLIAVILLTLLALFFGVLLGFAALKFKVEGNPIVDELEAILPQTQCGQCGYPGCRPYAEAIANGDKVNKCPPGGTATMEKLASLMGVEPEPLNAEAQSQVKKVAYIREDECIGCTKCIQACPVDAIIGAGKLMHTVLTADCTGCDLCVEPCPVDCIDMIPVGQNLKNWNWRLNAIPVTLIQETPHEEKRG",
    "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLKFQTVRGGLRLLGVRRSSTAPVASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELGIRTVAVYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENGVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTNSPINSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPATHLDPQLRSRLTSDSVKLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVSEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIPFLQNVLNNQQFLAGIVDTQFIDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKVSPSPVDPIVPVVPIGPPPAGFRDILLREGPEGFARAVRNHQGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFNNLFSIENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVFKFCEVAKENGMDVFRIFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSLEYYMGLAEELVRAGTHILCIKDMAGLLKPAACTMLVSSLRDRFPDLPLHIHTHDTSGSGVAAMLACAQAGADVVDVAVDSMSGMTSQPSMGALVACTKGTPLDTEVPLERVFDYSEYWEGARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQMLGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGIPHGGFPEPFRSKVLKDLPRIEGRPGASLPPLNLKELEKDLIDRHGEEVTPEDVLSAAMYPDVFAQFKDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFELNGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDVKVAAGAKVVKGQPLCVLSAMKMETVVTSPMEGTIRKVHVTKDMTLEGDDLILEIE",
    "output": "Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKCVTQLHYARKGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEV",
    "output": "Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK",
    "output": "Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIENIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLNAVFS",
    "output": "DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQVFREKQLLIQAIQKVKSDGKSIGLVPTMGALHEGHLSLVTNALKDSDQVIVSIFVNPTQFDNPEDLEKYPRNLNKDIELLEKETSDIWVFSPTANELYGDKILSQNFDFEGLESVMEGEFRAGHFNGVGTVVKHLFEVITPDKAFFGEKDFQQLQIIRKLIEKTGLPVEIVGCPILREDSGLARSSRNERLSFQNRKEAAFIYEVLQNANRLFGTESAEHTTNWVENQFKNNQHLKLEYFEIADSETLKKVNKKEKGKQYRAFIAAYSDGIRLIDNIALNN",
    "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKESFYIEGMTCTACSSGIERSLGRKSFVKKIEVNLLNKSANIEFNENETNLDEIFKLIEKLGYSPKKTLAEEKKEFFSPNVKLALAVIFTLFVVYLSMGAMLSPSLLPKSLLAIDNHSNFLNACLQLIGTLIVMHWGRDFYIQGFKALWHRQPNMSSLIAIGTSAALISSLWQLYLVYTDHYTDQWSYGHYYFESVCVILMFVMVGKRIENVSKDKALDAMQALMKNAPKTALKIQNDQQIEVLVDSIVVGDILKVLPGTLIAVDGEIIEGEGELDESMLSGEALPVYKKVGDKVFSGTFNSHTSFLMKATQNNKNSTLSQIVEMIHNAQSSKAEISRLADKVSSVFVPSVIAIAILAFVVWLIIAPKPDFWWNFGIALEVFVSVLVISCPCALGLATLMSILVANQKASSLGLFFKDAKSLEKARLVNTIVFDKTGTLTNGKPVVKSVHSKIELLELLSLANSIEKSSEHVIAKGIVEYAKEHNAPLKEMSEVKVKTGFGISAKTDYQGTKEIIKVGNSEFFNPINTLEIQENGILVLVGRAINEKEDELLGAFVLEDLPKKGVKEHVAQIKNLGINTFLLSGDNRENVKKCALELGIDGYISNAKPQDKLNKIKELKEKGRIVMMVGDGLNDAPSLAMSDVAVVMAKGSDVSVQAADIVSFNNDIKSVYSAIKLSQATIKNIKENLFWAFCYNSVFIPLACGVLYKANIMLSPAIAGLAMSLSSVSVVLNSQRLRNFKIKDH",
    "output": "Probably involved in copper export."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKDSNRCCCGQFTNQHIPPLPSATPSKNEEESKQVETQPEKWSVAKHTQSYPTDSYGVLEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVISHVGDALKDHSSKSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQTMSNPLSKLSVLNNSHTHFILADNGTLGKYGAEVKLRRLLEKHISLQKINTRLGQGVPLVGLVVEGGPNVVSIVLEYLQEEPPIPVVICDGSGRASDILSFAHKYCEEGGIINESLREQLLVTIQKTFNYNKAQSHQLFAIIMECMKKKELVTVFRMGSEGQQDIEMAILTALLKGTNVSAPDQLSLALAWNRVDIARSQIFVFGPHWPPLGSLAPPTDSKATEKEKKPPMATTKGGRGKGKGKKKGKVKEEVEEETDPRKIELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELYNTRLGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYTRKNFRTLYNNLFGPKRPKALKLLGMEDDEPPAKGKKKKKKKKEEEIDIDVDDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEESMAKALVACKLYKAMAHESSESDLVDDISQDLDNNSKDFGQLALELLDQSYKHDEQIAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILLPPTILFLEFRTYDDFSYQTSKENEDGKEKEEENTDANADAGSRKGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQNQPYMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHIYIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETFMKTSLQTVDLRLAQLEELSNRMVNALENLAGIDRSDLIQARSRASSECEATYLLRQSSINSADGYSLYRYHFNGEELLFEDTSLSTSPGTGVRKKTCSFRIKEEKDVKTHLVPECQNSLHLSLGTSTSATPDGSHLAVDDLKNAEESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVIHGQDKSDVQNTQLTVETTNIEGTISYPLEETKITRYFPDETINACKTMKSRSFVYSRGRKLVGGVNQDVEYSSITDQQLTTEWQCQVQKITRSHSTDIPYIVSEAAVQAEHKEQFADMQDEHHVAEAIPRIPRLSLTITDRNGMENLLSVKPDQTLGFPSLRSKSLHGHPRNVKSIQGKLDRSGHASSVSSLVIVSGMTAEEKKVKKEKASTETEC",
    "output": "Forms nonselective divalent cation-conducting channels which mediate the influx of Na(2+), Ca(2+), Mg(2+), Mn(2+), Ba(2+), and Ni(2+) into the cytoplasm, leading to membrane depolarization . Impermeable to zinc ions . In addition, forms heteromultimeric ion channels with TRPM3 which are permeable for calcium and zinc ions . Essential for the depolarizing photoresponse of retinal ON bipolar cells. It is part of the GRM6 signaling cascade. May play a role in metastasis suppression (By similarity). May act as a spontaneously active, calcium-permeable plasma membrane channel."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKPLISREQRFYESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESETVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCLDRRSEMRLKHLDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDFAHSTFKGFRDDPTVHDGPDRGYVFGLENLISIMEQMRDENQ",
    "output": "Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPKYYCEYCDIYLTHSSPVGRRQHVQGRKHISAKIEYFQNLLREEGITPQNFLGFLGPRALNNILGNPMMNNMMPGNFPMHMKHNNMKHHSHYSRRSHRHHMPHGRYGRERHGHYSYSSKYHSHPMHMNSSSMSSMSGFPYNEHSGNFFSLSNSMHGNGKMGNMVIRDLVSNVNIENDLVKDNPNEERNGDSAIANQPSTMHHEEDQDDPANATGGTANNNDNVSINA",
    "output": "Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGKKRINEVSTTEGAPAEKKKKVEKWLNTSSEDGEGTKKKKRPWRNKVRKLAAKKAAAERRVENSEESTILEPVATAEEATKKKKKRGPKKKKYKPEAAEVEKKNEEGDTVKENPIAEAKKRLDAGRFRMLNEKLYTCTGSEAFDFFKEDRTAFDLYHRGFADQVKKWPNHPLREIIRWLQAKPDKQAVFDLGCGEAKIAEAVGEKHTIRSFDLVAVNDRVESCDMSKLPAEDGSADVVIFCLSLMGTNLYDFIKEARRVLRTGGVLKIGEVTSRFVSIKQFCEAINKMGFETTNRRQLTDYFMMFDFRKIDKVEQKRPYGLKLKPCLYKKR",
    "output": "Probable methyltransferase required to silence rDNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFNLLKPKGASKRRKIVGRGPGSGLGKTSGRGQKGQKARNTSPRLGFEGGQTPLYRRLPRKGFSNSDYKLEYAIVNLGDIDKKFKDGQVVNYDTLLENKLIKKKNKKIKILSNGKLTKKVSFEVSKISKSAESLVIKIGCTIQLV",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVAAAPKK",
    "output": "May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. In lens epithelial cells, stabilizes the ATP6V1A protein, preventing its degradation by the proteasome ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKCIVGLGNPGAKYTNTRHNIGFLAIDALAKEHGIKLTESKFKAVFGTGMIKGERVVLVKPLTYMNLSGEAVRPLLDFYKIAVEDVLVIYDDLDLPLEKMRLRSKGSAGGHNGVKSLIQHLGTQDIKRLKLGVGRPPAPIQVIDWVLMPFAKSEQTTLQHVLSDSVNIATDFIDTPFLALMNRYN",
    "output": "The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS",
    "output": "Catalyzes the synthesis of activated sulfate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKKGVTYPLKIDTNLSTVSSSVNYNDIECVDIKSNGHYIVKFMYREWVGPLNLMTTQKTSIKISIDLKEQTVTCTHTDKKKTVYRWGEFPNKKETEQNKKEDNPVQYETFLSSNFNSEKYVNDLFTHKTDQQATVHLQYLENRKLGCIDHLKKDVYKNHLIFIGASKEIANSEVDMLDFRNLISDYGNVMSSLQNISISWDHYKVKKSGKIDFEPLSPATEPIQWLTTAPNELSVSIEQREFEVAVGLVEKINKIYESNPKVEIVMQTHPLKDQIENKVKILTDKLMNELRSPLLKANQIKDTISLLVRLSQNDKAKSIFLESRSHSINQAIKKIVFSGDLNRFIGELARVIFNSINSTCNDFTNSFPSYMNSGLVSWIIEELVLISDIFNRQVFILDNFYSISQAIRIIESHCEMMDQTGLSIGFYWNLLLQPHVEQLIVNYEIKIRDSMLHQLMDEKWNGVSNWDYEVKSQLNSLPSSLKNSGTPNSGGSGISNNNSNNNNNYQSPIINNNFNSGGGNKKIGLTFQQMHQDNLNNMEDIDQGRLKLTSSTIFLNTIIQKFAIDICQIITIDLIPVISQSLGSIFKDYMSYLKNEIQKEYLSDTQCLAIISDSVYIVDDLVSRIATRFEDATGEKLNNLTQLSSLLYSYFESIRDQYSTRKALELVDNSMNWEEQEYQVEEELDPFPKNFIVLSEALDRLAESIQTNVNVESVLPIASRIISEIVNIISNRFESTSNLVFGYGGLQHFILEMKYLATFAGKYPVEDSTFELINTMIRNHKEIYLNNTSDPKPLKTEEYFTSIIDNLVYQKAVYN",
    "output": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRLRTAIATLCLTAFTSATSNNSYIATDQTQNAFNDTHFCKVDRNDHVSPSCNVTFNELNAINENIRDDLSALLKSDFFKYFRLDLYKQCSFWDANDGLCLNRACSVDVVEDWDTLPEYWQPEILGSFNNDTMKEADDSDDECKFLDQLCQTSKKPVDIEDTINYCDVNDFNGKNAVLIDLTANPERFTGYGGKQAGQIWSTIYQDNCFTIGETGESLAKDAFYRLVSGFHASIGTHLSKEYLNTKTGKWEPNLDLFMARIGNFPDRVTNMYFNYAVVAKALWKIQPYLPEFSFCDLVNKEIKNKMDNVISQLDTKIFNEDLVFANDLSLTLKDEFRSRFKNVTKIMDCVQCDRCRLWGKIQTTGYATALKILFEINDADEFTKQHIVGKLTKYELIALLQTFGRLSESIESVNMFEKMYGKRLNGSENRLSSFFQNNFFNILKEAGKSIRYTIENINSTKEGKKKTNNSQSHVFDDLKMPKAEIVPRPSNGTVNKWKKAWNTEVNNVLEAFRFIYRSYLDLPRNIWELSLMKVYKFWNKFIGVADYVSEETREPISYKLDIQ",
    "output": "Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly PDI1 isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on PDI1 to transfer oxidizing equivalent. Also able to oxidize directly the PDI related protein MPD2. Does not oxidize all PDI related proteins, suggesting that it can discriminate between PDI1 and related proteins. Reoxidation of ERO1 probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNCTKGGGFPLLFCAVICLMAQQGACNVVLIANNTTLSFDDVEATFTPEVKDSGVNGAIYAVEPLDACSPLRKKAANGPVSPFALVIRGGCQFDDKVRNAQNAGFKAVIVYDDEDSGVLVSMAGSSSGIYIYAVFLSKASGEVLKKYSGQSDVEVWILPVYENSAWSIMAISFTSLLAMAAVLATCFFVRRHQIRRDRGRIPVTREFHGMSSQLVKAMPSLIFTKVQEDNSTSSSCAICLEDYSFGEKLRVLPCRHKFHATCVDMWLTSWKTFCPVCKRDASAGTSKPPASESTPLLSSVIHLSAESTALSSFRSTVAVSPPRPIRRHPSSQSTSRAYSISSAPRNYNLQRYYTNSPYISTSRSNVDLANMSSQWSHTPHQASMHSLRSGHLSLPINIRYTIPHVSRSDYGSASLGLSHDSCSHHGSPSYYHSSLGQQRSYLMHRTESGPSLSTMVLQSPQ",
    "output": "Involved in the trafficking of vacuolar proteins. May function as a sorting receptor for protein trafficking to the protein storage vacuole (PSV) (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGSGAGELGRAERLPVLFLFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGGGLVAQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPVPSDPQAELQFYLVVALALISVLFLLAVILAVALRLRRSSSPAAWSCFQPGLCVKSGPVVPPNYSQGTLPYSYNLCVAHTGKTEFNFLKCSEQLSSGQDILCGDSSGALFPLCNSSESTSHPELQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK",
    "output": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQFIPSPAMVFDGSLNLDPLVSGKPPEETTVVVAMSGGVDSSVVAALLHERGYKVIGATMQLHSSSPASGAKSCCGSVDIYDAKRVASTLGFPHYVLDYEEVFRREVIDDFINSYKRGETPIPCVKCNQTVKFRDMLKAARAIGGDVVATGHYVRRVEIAGEQQILRGKDPQKDQSYFLFSVTSEQLKFLRFPLGDLAKSNVRLLAQQLNLEVADKPDSQDICFVPENSYREVLRNLDPASVKKGKIVHVDGRLLGEHDGISNFTVGQRRGLNISAPYPLYVVRLDAAQNTVVVGPQSALMKRALFVKNLNWLPDYNIPKRGLAVDARLRSSGATVRATITSDGDGYGTVVLEEDCVVSPGQACVLYDKERLLGGGWIYNKLCHEGA",
    "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSNLFDSDSPTNLAEYSVSELSGSIKRTIETAFDQVRVRGEISGYRGPHSSGHAYFALKDDRARIDAVIWKGTFSRLKFRPEEGMEVIATGKVTTFPGSSKYQIVIETLEPAGAGALMALIEERKRRLGAEGLFDAARKKRLPFMPHVIGVVTSPTGAVIRDILHRISDRFPVHVLVWPVKVQGEGSGEEVANAIRGFNALEPASAISRPDVLIVARGGGSLEDLWSFNDEIVVRAAAESRIPLISAVGHETDWTLIDYAADVRAPTPTGAAEMAVPVKAELEAQAAALAARLQGCMNRQMDQRRQSVRSLMRAFPSLDQLLALPRRRFDEAAAGLGRGLELNTINKRRGFERVIAHLRPDLLSGRISERRQMLNERMVRAERMVERLIDRSASRVERAEAILASLPARLKAQTDRSRERLGNLTRHADTAIRHQLTRARAELSAQDRVLQSLSYKNVLRRGYAVIRDEDNRPVSQAAALSAGMGIAIEFADGRIGAMTTEGGTPPGGAKKRSTKPAEPTKQGSLF",
    "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MARKSLIQRERKRQKLEQKYHLIRRSSKKEISKVSSLSDKWEIHGKLQSPPRNSAPTRLHRRCFSTGRPRANYRDFGLSGHILRERVHACLLPGATRSSW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRPSRRAPDEMRAVSLERGVVKYAEGSCLVKFGDTHVLVTATLEDRLPPWLKGQGRGWITAEYGMLPRATLERTRREASAGKQTGRTVEIQRLIGRSLRTAIDLEALGERQITVDCDVLQADGGTRTASITGAWVALADCIRWMKARNMIKTEVLRTNVAAVSCGIYNGTPVLDLDYAEDSEAETDANFVMTGDGRIIEVQGTAEKTPFSEAEFLALMALARKGVGRLVDLQKMAVA",
    "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPFRSNNPITRDELLSRFFPQFHPVTTFNSGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGAVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRPLRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTEQHLQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ",
    "output": "Catalyzes the phosphorylation of thiamine to thiamine phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQSGDFIKTQEFSQTPGQEDRLMTNETIDWDKKVAPSAIYEERAVVFPVLHGPMGEDGSVQGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEVEEELTYPVFTKPSNMGSSVGISKSENQEELRQALKLAFQYDSRVLVEQGVNAREIEVGLLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFRAIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGITYPDLIERLVELAKESFDKREAHLL",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARQINDTFLRACRGEQTSYVPVWYMRQAGRSQPEYRALKEKYSLFEITHQPELCAYVTRLPVEQYGVDAAILYKDIMTPLPAIGVNVEIQGGIGPVIANPIRSLQDVERLGEIDPEHDVPYVFETIRLLVNEQLDVPLIGFAGAPFTLASYMIEGGPSKNYHKTKAFMYAEPKAWFALMDKLAEMTIRYVRAQIRAGASAVQIFDSWVGAVSADDYRTFIKPAMARIFAALREEGAPLIMFGVGASHLVHEWNDLPLDVIGLDWRLSIREARRQGIAKAIQGNLDPAVLLAPWDVIEERVKRILDEGMERPGYIFNLGHGIFPDVQPATLKRLTAFIHEYTSTN",
    "output": "Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTTALDQLKQYTTVVADTGDFQQLAQYQPQDATTNPSLILKAVQKDAYKPILEKTVRDHRNESTDFIIDRLLIAFGTEILKIIPGRVSTEVDARLSFDAKRSIDKAHELIKLYEAAGIERDRILIKLASTWEGIRAAETLQKEGIKCNMTLLFSLVQAAACAEAGAQLISPFVGRIYDWYKKQAGADWDEAKNGGANDPGVQSVRRIYTYYKTFGYKTEVMGASFRTTSQIVELAGCDLLTISPDLLQKLHDSNETVTRKLSPDALHDKPTERVAIDEASFRFQLNDEAMATEKLAEGIRVFAADAVKLEKLIEALR",
    "output": "Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQVTADVSQMAEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSKEKQVVKEGATTLLWFEHPAERFLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSASRLPEAGEDLELKMGENWRRTGTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLHIEPLPYSLEE",
    "output": "Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV",
    "output": "In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling . Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1 . May also play a role in microtubule-mediated protein transport (By similarity). Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKHFIGNDWDHVLAPVFESGEYHKLHVFLKKEYQTKQIYPDMYHIFTAFKLTPFKDTKVVILGQDPYHNPSQANGMSFSVMPGTPLPPSLRNIYKELYDDVGAQPVNHGYLKRWADQGVLLLNAVLTVPYGQANGHQGKGWEMVTDAAIKALSERGQVVFILWGRFAQNKIPLIDQDKNVIIKSAHPSPFSANRGFFGSRPFSRCNAALKEFGRAPVDWQLPPNTEA",
    "output": "Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MILTRIILHNYRNIEAAELCPEENFNLLCGDNAQGKTNTLEAIYLLGHFKSFRRGRNEELIGSADRHTRVQGEFLRDGLRETVSITITGDKKNIEINGKRPRQSNEMFGRFPSVLFAPEEVSLPKGFPAGRRALLDRALCQTRPSFLDHARAYQRCLRQRNILLKSGAAAPIVLPWTEELIQTGAMVRLARRRYLDRLLPLLRDIYREICSGRESVNLVYPSESDNLSDLKEELRSNLEREQSRETKYGMTMVGPHRDDPVFMVDDRVLGLYGSQGQQRSFILAFKTAQIIDLEKETGYTPLLLLDDMTSELDRKRQDYFFRFLHQRQGQVFITCTELSPLQNAGFNRMRTFRVREGKLCDYQ",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKIYDWFEERLEIQSIADDISSKYVPPHVNIFYCFGGITFTCFLVQVATGFAMTFYYRPTVAEAFTSVQYLMTQVNFGWLIRSIHRWSASMMVLMMILHIFRVYLTGGFKKPRELTWVTGVLMAVCTVSFGVTGYSLPWDQIGYWAVKIVTGVPDAIPVIGQVLLELLRGGVAVGQSTLTRFYSLHTFVLPLFTAVFMLMHFLMIRKQGISGPL",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSWQAYVDEHLMCDVGDGQGHHLTAAAIIGHDGSVWAQSANFPQFKPQEITDIMKDFDEPGHLAPTGMFLAGLKYMVIQGEPNAVIRGKKGAGGITIKKTGQSMVFGLYEEPVTPGQCNMVVERLGDYLIEQGL",
    "output": "Binds to actin monomers and regulates the organization of the actin cytoskeleton . At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations . At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate . Acts redundantly with PRF4 to regulate apical actin polymerization at the tip of pollen tube and control polarized pollen tube growth . Functions probably by favoring formin-mediated actin polymerization at pollen tube tips ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSTMTPAEIVSELDKHIIGQDKAKKAVAVALRNRWRRQQVAEPLRQEITPKNILMIGPTGVGKTEIARRLAKLADAPFIKIEATKFTEVGYVGRDVDSIVRDLIEISVKQTRETEMRKVRSKATDLAEDRILDVLLPQPRAVGFGASVEHANDDNNATRQTFRKRLREGQLDDKEIELDIEQPTVGMDIMAPPGMEEMTEQIRSMFSNLGSGKKQRRKVKIKEALKLLTDEEAAKMLNDEEVKTKAVQNVEQNGIVFLDEIDKITSRNHEGGGGEVSRQGVQRDLLPLVEGTTINTKYGMVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELDSLSVKDFEAILVATDASLVKQYQALLATEDVALEFADDGIRRLAEIAYAVNEKTENIGARRLYTVIEKLLEEVSFAAGNHAGQSVTIDAAYVDRALGEVSKDEDLSRYVL",
    "output": "ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTNIRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGICLVIQIITGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGVLLLILILMMLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMLFPILHMSKQRSMMFRPLSQCVFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFMIILLILPAISLFENTLLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKSVASPLCQFHGVFCLYQCRQCLAYHVCDGGAECVLLHTPESVICELTGNCMLGNIQEGQFLGPVPYRTLDNQVDRDAYHGMLACLKRDIVRYLQTWPDTTVIVQEIALGDGVTDTISAIIDETFGECLPVLGEAQGGYALVCSMYLHVIVSIYSTKTVYNSMLFKCTKNKKYDCIAKRVRTKWMRMLSTKDT",
    "output": "Plays an important role in the expression of late genes . May play a role in viral replication ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDGVSNWPAPSTPTPVHATLTIPGSKSQTNRALVLAALATPQGTSTISGALRSRDTDLMIGALQTLGFDVESAGTDSDLRVGGGLGPAAGARVDCGLAGTVLRFLPPVAALSTETVEFDGDEQARARPIAPLLAGLQALGVRIDGDGLPFRVRGEGSVAGGTVEIDASASSQFVSGLMLSGALFRDGLTIVHTGESVPSAPHVAMTVSMLRDAGVEVDDTKTNRWTVRPGPVAARHWTIEPDLSNAVPFLSAGVVSGGAVRITGWPAVSTQPAGAIMAILEKVGAVVRQTESYLEVQGTRQYQGFDVDLHDVGELTPAVAALAAVATPGAVSRLRGVAHLRGHETDRLAALSAEINGLGGQCEETDDGLVITAAPLHGGVWHSYADHRMAMAGAIVGLRTPGVEIEDIATTAKTLPEFPQMWADMLAGQTATDPEAGA",
    "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKNEKLPQFQPHFLAPKYWLFWLGVAIWRSILCLPYPILRHIGHGFGWLFSHLKVGERRAAIARRNLELCFPDMPENEREVILQENLRSVGMAIIETGMAWFWSDSRIKKWSKVEGLHYLKENQKDGIVLVGVHFLTLELGARIIGLHHPGIGVYRPNDNPLLDWLQTQGRLRSNKDMLDRKDLRGMIKALRHEETIWYAPDHDYGRKNAVFVPFFAVPDTCTTTGSYYLLKSSQNSKVIPFAPLRNKDGSGYTVSISAPVDFTDLQDETAIAARMNQIVEKEIMKDITIYMWLHRRFKTRPDEKTPSLYD",
    "output": "Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MELSPRAAELTNLFESRIRNFYANFQVDEIGRVVSVGDGIAQVYGLNEIQAGEMVLFANGVKGMALNLENENVGIVVFGGDTAIKEGDLVKRTGSIVDVPAGKAMLGRVVDAMGVPIDGRGALSDHEQRRVEVKAPGILERKSVHEPMQTGLKAVDSLVPIGRGQRELLIGDRQTGKTTIAIDTILNQKQINSRATSESETMYCVYVAIGQKRSTVGQLIQTLEEANALEYSILVAATASDPAPLQFLAPYSGCAMGEYFRDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKRSDQTGAGSLTALPVIETQAGDVSAYIPTNVISITDGQICLETELFYRGIRPAINVGLSVSRVGSAAQLKAMKQVCGSSKLELAQYREVAAFAQFGSDLDAATQALLNRGARLTEVPKQPQYAPLPIEKQILVIYAAVNGFCDRMPLDRISQYEKAIPNSVKPELLQALKGGLTNERKMEPDAFLKERALALI",
    "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPGFFAGVCTVVTKLMSCVQPRVAVFGKKDYQQLMIVRRMCQQLALPVDIIAAETVRDEDGLALSSRNRYLTTDERKEAPELAKTLQRVRDGVLGGERDLGKLEQTARAHLAERGWAPDYISIRRRANLIAPSAAELEAGEPLVVLAAAKLGATRLIDNLEI",
    "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSVPSRKIRLIMELRQNGVSATPVLAAIERVPRDAFVSAPFSDQAYENTALPIGCGQTISQPLVVGLMTQALDLNDRHKVLEIGTGSGYQTAVLARLCRRVYTIERHGALLREAEARLTALGLHRTVVTREGDGGRGWPEQAPFERILVTAAALDIPKVLVAQLAIGGVMVLPVGKESGAQEVVRVRRTAEDALVTERLFPVRFVPLVDGLPPRDAPGA",
    "output": "Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSPSQLIGFLLLWVPASRGEIVLTQSPDFQSVTPKEKVTITCRASQSIGSSLHWYQQKPDQSPKLLIKYASQSISGVPSRFSGSGSGTDFTLTINSLEAEDAAAYYCHQSSSLP",
    "output": "V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKTKTGIFSGSFNPIHIGHLALANYLCEFEGLDEVWFMVTPHNPFKNQADLWPDELRLQLVQLAIEGYPRFRVSDFEFHLPRPSYTIHTLNRLKQEYPEREFQLIIGSDNWMVFDRWFESERIVSENKILVYPRPGFSVDKSQLPPNVHVADSPIFEISSTFIREALATGKDIRYFLHPAVYKRIIQQTDSIDSSHSCHT",
    "output": "Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAPGSRGERSSFRSRRGPGVPSPQPDVTMLSRLLKEHQAKQNERKELQEKRRREAITAATCLTEALVDHLNVGVAQAYMNQRKLDHEVKTLQVQAAQFAKQTGQWIGMVENFNQALKEIGDVENWARSIELDMRTIATALEYVYKGQLQSAPS",
    "output": "Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension . As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor .; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTVTGIIAEFNPFHNGHKYLLDHAEGIKIVAMSGNFVQRGEPAIVDKWIRAQMALENGADLVVELPFFTAVQSADYFASGAVDILSRLGIDSLTFGTEEVLDYQTIADVYSEKSEEMEAFVESLPSDLSYPQKTQKMWEKFAGVDFTGNTPNHILGLAYAKACAGKGITLNPIQRQGAGYHSLDKEVSFASATSLRLHKEDSNFVDKFMPNSKLFQTSPQVSWDNYFQLLVYQILTNPDLTSVFQVNEEIASRLKAAVREISSVEELVDKVATKRYTKARVRRILTYILVGAVDNSLPKSIHVLGFSQKGQFHLKSVKKSVDIVARIGRKPWDMLTQQADNVYQLGNPELCEQNFGRVPIRVK",
    "output": "Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDVLEVAARATGTGPVCDACLGRLVADRSFGLSNAERGSALRTSLALRDDEDYEPVETADCWVCEGRCTEFDEWAERAAEAVEDVEFATYNVGTRPPPLIEENEALLREEAGLDDDAGEPFKSEFNREVGKRFGRLTETEVSFDRPDVQFTIDLAEDEIDAKVNSTFVYGRYRKLERDIPQTEWPCRECKGSGRQGADPCDHCGGSGYLYDDSVEEYTAPVVEDVMDGTEATFHGAGREDVDALMLGTGRPFVIEVEEPRRRRVDTDRLQADINAFADGAVEVEGLRLATYDMVERVKEHDAAKRYRAEVAFDADVDADALAAAVEELEGTTVEQYTPNRVDHRRASITRERDVYEATAELDDARHAIVEIHGEGGLYIKELISGDEGRTEPSLAGLLGVGAEVTALDVVAVEGEDEPFEREEFFRE",
    "output": "Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGSTAGDVAAVVDEEACMYAMQLASSSILPMTLKNAIELGLLEVLQKEAGGGKAALAPEEVVARMPAAPGDPAAAAAMVDRMLRLLASYDVVRCQMEDRDGRYERRYSAAPVCKWLTPNEDGVSMAALALMNQDKVLMESWYYLKDAVLDGGIPFNKAYGMTAFEYHGTDSRFNRVFNEGMKNHSVIITKKLLDFYTGFEGVSTLVDVGGGVGATLHAITSRHPHISGVNFDLPHVISEAPPFPGVRHVGGDMFASVPAGDAILMKWILHDWSDAHCATLLKNCYDALPENGKVIVVECVLPVNTEATPKAQGVFHVDMIMLAHNPGGKERYEREFRELAKGAGFSGFKATYIYANAWAIEFIK",
    "output": "Catalyzes the conversion of caffeic acid to ferulic acid and of 5-hydroxyferulic acid to sinapic acid (By similarity). The resulting products may subsequently be converted to the corresponding alcohols that are incorporated into lignins . Can use the flavone tricetin (5,7,3',4',5'-pentahydroxyflavone) as the preferred substrate and give rise to its 3',5'-dimethyl derivative, tricin (3',5'-dimethoxy-5,7,4'-trihydroxyflavone), as the major product, and selgin to a lower extent (Ref.3). Tricin exhibits potential benefits for human health including relaxant effect on smooth muscle of intestinal tissues, antioxidant effect, antihistaminic activity, and growth inhibition of human malignant breast tumor cells and colon cancer cells (Ref.3). Can also use luteolin, quercetin and 5-hydroxyferulic acid (5HF) as substrates (Ref.3)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKHYVAVDIGASSGRLILGKLVNEKLQLEEIHRFKNGFTYRDGHERWEIDQLMQEIFIGLEKVKQLGISECVLGIDTWGVDYVLIGASGEKLADPISYRDKRTLNAVQNLTSEYPREYIYKKTGIQFMELNTLYQLYVEERDLLERAEKILLIPDYIGYVLTGVKVAETTNSSTTQMLNLREQLFDKDLLSHLNIDVEKFAPLTDAGTYLGEVKEDWLKMYDIPNCDVVTVATHDTASAVVGTPAEGENWAFLSSGTWSLIGMELSAPINNEVAFKENYTNEWGAYGTYRFLKNIMGLWIVQEIARMDDYKHSFAEMAEEAGNYPYFKQIINVNDARFNNPENMVDEIRLYCRETGQTVPETIGELTNCVYGSLALYYALELEKMTEITGKKIEKLYIVGGGSNVAMLNQLTAKLAGIEVFAGPSEATAIGNLVVQMINQGEIESMRAGRKIIRNSFEIGEFSCGDVRFEEIKERFTKVLEFN",
    "output": "Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKVLSKLKPAPGLWLHKAPTPKPGRDEVLIKIKKTAICGTDLHIYKWDEWAQKTIPVPMHVGHEFVGEIVEVGEAASALAVGDRVSGEGHITCGDCRNCRAGKRHLCRYTVGVGVNRPGAFAEYLVIPAKNAYKIPAKISDDIAAILDPFGNAAHSALEFDLVGEDVLITGAGPVGLMSAAIARHVGARHVVITDVNDYRLALAEKVGVTAAVNSTKTPLTETMKNLGMTEGFDVGLEMSGNAEAFRSMLTVMNNGGKIAFLGIPPEPFAIDWNQVVFKSLLIKGIYGRRMFETWYKMTNLLLSGLDISPIITHEFPMKDFQQAFDVMLSGKTGKVILNWEQ",
    "output": "Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNEQFIQFPQIDPIIFSIGPIALRWYGLMYLIGFGFAYWLGMRRAKNSNGVWTTEQVDQLIYTCFWGVILGGRIGDVFFYNFDRLLQDPMFLFRIWEGGMSFHGGLIGVIVAMIWVSFRQKRSFWNTADFIAPLIPFGLGMGRIGNFINDELWGRITDVPWAVLFPSGGYLPRHPSQLYEFFLEGVVLFFILNWFIKKPRPAGSVAGLFLIGYGVFRFLVEYVRDIDPNVNTVDDLITRGQLLSLPMIIGGLAIMIWAYSRKKA",
    "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVNVPEQQSPETAAVCKNEKLLNKLESSSYNKSNMDQLAVIVNFLERKNINYILNVVPVMQDERKMSKRKKKVINNNKYILFNSWYTKIKQPEWPSSPAMWDLVKNKPELADFVFIFDHTEKLGKKMADRSTSSSSSENAAIPASKKRQTVVLTNANLAELKESCEMRDKLYSEFYSLLNETFNHNVAPLLSNIYDEVLTRDFITKSMAKFKTVALKLPVAPSTTEYVPTPISGSRKRKSSVPAKQRSSIKTRRNTVAPALLMVSDNTQDTNMSD",
    "output": "Plays a role in both early and late gene expression."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNEEQRLANQQVNQPKKEDKPEKDYSKYFEKVFTAPSLKDAKKRGKEDVKYHKDFSIDEQFAGMGKDRTFYIRTYGCQMNEHDTEVMAGIFMQLGYTPTEIIEEADVVLLNTCAIRENAENKVFGELGFLLKYKRKNPEMLIGVCGCMSQEESVVNKILRSYPHVDMVFGTHNIHRLPNILKEAYMSKEMVVEVWSKEGDVIENLPKKRLGSIKAWVNIMYGCDKFCTYCIVPYTRGKERSRRPEEIIAEVRELAAAGYQEIMLLGQNVNAYGKDFEDIEYRLGDLMDALRKIDIPRIRFTTSHPRDFDDHLIEVLAKRGNLVEHIHLPVQSGSNDILKIMARKYTREHFLTLVEKIKAAIPEVTLTTDIIVGYPNETEEQFEETLSLYREVGFEAAFTYIYSPREGTPAAKMVDNVPEEVKKERLQRLNEVVGEYSRKALERLNGEVVEVLVEGTSKRRDDVLAGYTRKNRLVNFKGPAEVIGQLVKVKIIETTSYSLTGEFLEVVKNEKVEA",
    "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MHALSQEPTVWHGTTILTVRKGGRVVVGGDGQVSIGQTVIKSNARKVRKLGKGDVIGGFAGATADAFTLFERLESKLEQYPGQLTRAAVELAKDWRTDRYLRRLEAMMIVADKEVSLVLTGTGDVLEPEAGVMAIGSGGNYALAAARALIDTDKDAESIVRKSLDIAADICVYTNRNITIEALSAE",
    "output": "Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATILKQKLKTFFVPTAITLLLSACNSTSLFENSVTYLIKQEAYASSEFYINKAEQTLNSQDKITYQLLAVRKLIDENKVVEAQNTLNDLTTRLNIMEQNPLQQLEYQLVTAQLAALKGNNHQAEVTLQHISAANLSHSQLLRFYQTQAKIAENSKNTIEAVRIRSLIATQLVDNKLRQENNDKIWSLLRNANRGMLSSAQAGAGEMELAGWLALIEIYNQSVSTPAQMPQNINYWKRLYPNHSALAVMPTELQRVFNFQQTLLNNVALLLPLSGDAKILGEIIKKGFDDAKEQDPTIVQVFDTDSNSIENILMQAKQQGAQMIIGPLLKSRVNQMLASDQIRDINVLALNATQDVKPIVGVCYYGLSPEAEARSGADRLSRDGYTKAIVVAARDEFGQRSAEAFAQRWRQLTNTDADIRYYNQPLDVITTIQNSANNLQETALYALGNAEQLLEIKQGLENSTIAGQLAIYTASRSNSPNNGIEFRTAMEGVKFSEIPLLADHNSNEYQKAYSLADSDFSMMRLYAMGSDTWALANKFNEFRQIPGYSISGLTGNLNAGPNCNIERNMTWLQYHNGAVETTN",
    "output": "Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRNSTKQEDLVKAFKALLKEEKFSSQSEIVHALQDEGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDVDYNDAVVVIHTSPGAAQLIARLLDSLGKSEGILGTIAGDDTIFTTPARGFSVKQLYEAILVLFEQEL",
    "output": "Regulates arginine biosynthesis genes."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSFDAKAFLATLTELPGVYRMLDIGGNVLYVGKAKNLKKRVASYFRENLSSPRIAHMVSQIASIETTATRTEAEALLLENNLIKSLAPRYNILFRDDKSYPYIVLSKGKFPRLGFFRGNPDRKADYFGPYPSSWAVRDSIHLMQKMFRLRTCEDTVFSNRSRPCLLYQIKRCSGPCVGFISADDYAADIQLAAMFLLGKQQEVTRRLTKSMEEASAKLAFEQAAVFRDQIQSLHQVQEKQFVSSSKGEDVDVLVAIKEAGQLCVNLAMVRGGRHLGDRPFFPTNAADSEPSDACAAFIRQHYAAHPAPARILSYPLPSEDEAGETEVALAELAGRPVPVQEGRGATHKAWVEMAIQNARLAILAKNQATAQQEQRLAALQDALQLPEPIARIECFDISHTMGEATVASCVVYEGNRMKKSDYRRFNIRDIQAGDDYAAMRQAVSRRYDSIAGGEGTAPDLILIDGGKGQVSSAFSALADLGLTHLPMIGVAKGEERKPGLETLIFPEGREPLQLPPQHPALHLIQEIRDEAHRFAITGHRAQRGKARKTSKLESLPGIGPARRKALVARFGGLPGVLAASIDQLAEVPGVSREMAEKIHSALH",
    "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAKIRRNDEVIVLAGKDKGKKGKVTKVLATGKVIVEGINLVKKHQKPVPALGIQGGIVEQEAAIDVSNVAIFNAATGKADRIGFRFEDGKKVRFFKSNGETVSN",
    "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTITPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEVEDNANFVDIVGTGGDGSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPAMRNIAPVRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGELRDGEVREYEIHPEDFGMQMVSNRTLKVESADESRVMLLEALGNKPGVAREIVTLNAGTALYSADVAGSIADGIQLARDAIASGRAREKVDELVRFTQQFKR",
    "output": "Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAIARLIVENFRNISAVDLEFDHGFNFLVGNNGSGKTSLLEALFYLGHGRSFKSSVTTRVIRYDQPHFTLHGRIRELQHEWSVGLQKQRKDGNTIVKINGEDGNKISDLAHLLPMQIITPEGLTLLNGGPSYRRAFLDWGLFHHQPNFHSAWSALHRLLKQRNAALNQTYDYNMLKPWDMELAKLAHQVSQWRADYAEALSPEIEQTCRLFLPELDIHVSFHQGWEKDTDYAQLLTENFERDKAIGYTVSGPQKADFRFKSNGLPVEDVLSRGQLKLLMCALRLAQGEHLMAQKNRHCIFLIDDFASELDETKRALLAQRLQNSNSQVFVTAISPEQLKQMQPEKHRTFQVVNGQIEQLL",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHKRKDRKIVVEIEHNYVPSNHKNLAYRAAQLFIEQYQLKQGVTISIDKEIPVSAGLAGGSADAAATLRGLNRLFDIGASLEELALLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKPPSAWVILAKPNLGISSPDIFKLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEPISVSKHPQIDKLKNNMLKSGADGALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVYLVRLLG",
    "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIYAEILAGGKGTRMGNVNMPKQYLPLKGKPIIVHTIEKFILNDRFEKIIIATPKDWINHTQDIIKKYIFDSRVIVIEGGTDRNETIMNGIRYVEKEFGLNEDDIIVTHDAVRPFITHRIIEENIDMALEFGSVDTVIPAVDTIVESTNHDFITDIPVRGNIYQGQTPQSFNMKTIQKHYNNLTDDEKQILTDACKICLLAGEKVKLVNGGISNIKITTPYDLKVANAIVQERINS",
    "output": "Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "GSSGMIPFPRV",
    "output": "Mediates visceral muscle contractile activity (myotropic activity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKMEDMSLSGLDNTKLEALAHDVYSDLVEDACLGLCFEVHRAVKQGYFFLDETDQESMKDFEIVDQPGVDIFGQVYNQWKNKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRIASSNNTSKSESDQEDNDDINDNDWSYGSEKKAKKRKSEKNPNSPRRSKSLKHKNGELSGSVNPDMYKYNYSSGISYETLGPEELRSILTTQCGVVSEHTKKMCTRSQRCPQHTDEQRRAVRVFLLGPSASTLPDADTMLENEAYEPPDGQLIMSRLHWDASSDISPSDSASSKASTNNSESKRPKKKKPSTLSLTPAGERDKAQERDRIAGSGSSGSSSQNALGLSSRKKRPKLAVPPAPSIYDDLN",
    "output": "Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFNHVTVLLKETVDGLDIKPDGTYVDCTLGGGGHSSYLLSQLTEGGRLIAFDQDEIAIQNAKEKFSSYGEQFITVKSNFRYLSEKLQELGITEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQDAPLTAYDVVNSWSYEQLVRIFFQYGEEKFSKQIARKIEAYRENKAIETTGELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALESAIEMVKPGGRVSVITFHSLEDRICKTTFKRNSTTPQLPPGLPIIPDEFKPKLKLITRKPILPSDIELEENNRARSAKLRIAEKR",
    "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDIAALREEYTRHGLSRDDLNVDPFKQFETWFKQACESQLLEPNAMSLATASDQGEPSLRTVLLKYFDNQGFVFFTNYESNKAKQIEENPYVALLFLWLPLERQVKIRGKAAKISTAESFRYFTTRPRGSQLGAWCSEQSSVISSRQLLEMKFEEIRRKFAQGEIPLPSFWGGYRIVPHYFEFWQGRPNRLHDRFSYTLQEDNTWEIHRLSP",
    "output": "Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAGTDREKALDAALAQIERQFGKGAVMRMGDRTNEPIEVIPTGSTALDVALGVGGIPRGRVVEVYGPESSGKTTLTLHAVANAQKAGGQVAFVDAEHALDPEYAKKLGVDIDNLILSQPDNGEQALEIVDMLVRSGALDLIVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKITSALNQSKTTAIFINQLREKIGVMFGSPETTTGGRALKFYASVRLDIRRIETLKDGTDAVGNRTRVKVVKNKVAPPFKQAEFDILYGQGISREGGLIDMGVENGFVRKAGAWYTYEGDQLGQGKENARNFLKDNPDLANEIEKKIKQKLGVGVHPEESATEPGADAASAAPADAAPAVPAPTTAKATKSKATAAKS",
    "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSWRSEYIWVEFIAGSRKPGNFFWAFILFLGSLGFLVVGISSYLDRNLLSLFPSQQINFFPQGIVMSFYGIAGLFISSYLWCTIIWNVGSGYDRFDTKEGIVCIFRWGFPGKNRRIFLRFLMKDIQSIRIEVKEGIYARRVLYIESRGLGAIPLNRTDENLTPREIEQKAAELAYFLRVPIEGF",
    "output": "Seems to be required for the assembly of the photosystem I complex."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAAWKSWAALRLCATVVLLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNHRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYIGGESPLKEKYIDAASELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDSILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSENENQEQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD",
    "output": "Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAVIGDKGLTQLRIGKNFNYESSFLNESQGFFILAQDCLNKIDKKTNKSKVAKTEETELKLKGVEAEVQDKVCHQVELISNNPNASQQSIVIPLETFALSASVKGNLLAVVLADNSANLYDITSQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSDKFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQMDKSLRELNSVKLPSSLNTIVLNHNKLYSLEKRGYVIEVDLNDFDSYNVYKTPTIGSFKFFSSNRLDKGVFYDKNRVYYDRYYLDYNDFKPKLYPVVEKSASKKSQKGEKGNAPIYLQERHKAKENKQPLEENKVKPRNSGFEEEEVKTRRPEPIRDQNNATQQGETKNNESKNAPVLKENAAKKEVPKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALEMNKK",
    "output": "Binds plasminogen, specifically, and in a concentration and lysine-dependent manner. Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin. Acquisition of plasminogen/plasmin could enable H.pylori to degrade host components."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSLPAGNAVGNWLLILTAIFGFLTLIWIPQASAECQTRSIYCYECDSWTDARCKDPFNYTALPRDQPPLMTCNGCCVKMVRHQRSRYEVVRRMCTSQLQINLFMVDHVCMMESSGNGHMCFCEEDMCNSSKNLYTKNGYQHLINIMIIWLIGILLNQLSNR",
    "output": "Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTGKALLKPHWLRVKAPQQQRIGEVAELLKGLNLKTVCQEASCPNIGECFAGGTATFLIMGPGCTRACPYCDIDFDKSPRSLDPTEPERLSEAVAQMNLRHVVITSVNRDDLSDGGASQFVACIEAIRQRSPLTTIELLIPDFNGNWDALAKVMGAAPEVLNHNIETVPRLYKRARPQADYMRSLELLYQVRQGWPKVYSKSGLMVGLGETDAEVIEVLEDLRRHRVDIVTIGQYLSPSPKHLPVDRFVTPEQFEYFRSMGETELGFLQVVSTPLTRSSYHAGEVQRLMAAHPR",
    "output": "Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFALTAYRLRCAAWLLATGIFLLLAGCSEAKAPTALERVQKEGVLRVVTRNSPATYFQDRNGETGFEYELAKRFAERLGVELKIETADNLDDLYAQLSRAGGPALAAAGLTPGRQDDASVRYSHTYLDVTPQVIYRNGQQRPTRPEDLVGKRIMVLKGSSHAAQLAELKKQYPELKYDESDAVEVVDLLRMVDVGDIDLTLVDSNELAMNQVYFPNVRVAFDFGEARGLAWALPGGDDDSLMNEVNAFLDQAKKEGLLQRLKDRYYGHVDVLGYVGAYTFAQHLQQRLPRYESHFKQSGKQLDTDWRLLAAIGYQESLWQPSATSKTGVRGLMMLTNRTAQAMGVSNRLDPKQSIQGGSKYFVQIRSELPESIREPDRSWFALAAYNIGGAHLEDARKMAEKEGLNPNKWLDVKKMLPRLAQKRWYAKTRYGYARGGETVHFVQNVRRYYDILTWVTQPQMEGSQIAESGLHLPGVNKTRPDDDEGDGKL",
    "output": "Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAVEMFYDADADLSIIQGRKVAVIGYGSQGHAHSLSLRDSGVEVKVGLKEGSKSRDKVTEQGLDVDTPAEVAKWADVIMLLAPDTAQAEIFTKDIEPNLEDGNALFFGHGLNIHFGLIKPPANVTIGMVAPKGPGHLVRRQFVDGKGVPCLIAVDQDPKGEGQALALSYAAAIGGARAGVIKTTFKDETETDLFGEQAVLCGGTEELVKTGFDVMVEAGYEPELAYFEVLHELKLIVDLMYEGGIARMNYSVSDTAEFGGYLSGPRVIDADTKKRMQDILKDIQDGTFVKRLVANVEGGNKELEGLRKQNAEHPIEVTGKKLRDLMSWVDRPITETA",
    "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKAKFERLKPHVNVGTIGHVDHGKTTLTAAIATVAAITSGGEAKDYASIDSAPEEKARGITINTSHVEYDTPSRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSATDGPMPQTREHILLSRQVGVPYIVVFMNKCDVVDDEELLELVEMEVRELLSDYDFPGDDTPIIHGSATEALKGSQEKYGQPAVVELLNVLDTYIPEPERDIDKAFLMPIEDVFSISGRGTVVTGRVESGIVRVGDEIEIVGIRDTQKTTCTGVEMFRKLLDEGRAGENCGVLLRGTKREDVQRGQVLAKPGSITPHTKFDAEVYVLSKEEGGRHTPFLNGYRPQFYFRTTDVTGAIQLQDGTEMVMPGDNVEMGVELIHPIAMDKGLRFAIREGGRTVGAGVVANVLN",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSDINATRLPIWGIGCNPCVGDDVTSVLTRGEA",
    "output": "Major toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "QHWSHGWYPG",
    "output": "Stimulates the secretion of gonadotropins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMLSVFGLSVPISATELLLASFVFCLVFWVVRAWQPRVPKGLKSPPGPWGWPLLGHVLTLGKNPHLVLARLSQHYGDVLQIRIGSTPVLVLSGLDTIRQALVRQGDDFKGRPNLYSFTLISEGQSMSFSPDSGPVWAARRRLAQNALKSFSIASDPASSSSCYLEDHVSKEAEYLIGKFQELMAKVGHFDPYRYVVVSVANVICAMCFGRRYDHDDQELLSIVNLSNEFGDGTASGNPVDFFPILRYLPNPALDFFKDVNEKFSIFIHKMVKEHYKTFEKGHIRDITDSLIEHCQDKRLDENANIQLSDEKIVNVVSDLFGAGFDTVTTAISWCLMYLVTSPNVQEKIQKELDTVIGRERQPRLSDRLQLPYMEAFILEMFRHTSFVPFTIPHSTTKDTSLSGFYIPKERCVFVNQWQINHDQKLWGDPSEFRPERFLTPDGTINKALSEKVILFGLGKRKCIGETIARLEVFLFLAILLQQVEFSVPQGTKVDMTPIYGLTMKHARCEHFQVRMRT",
    "output": "A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2, as well as D-ring hydroxylated E1 and E2 at the C15alpha and C16alpha positions. Displays different regioselectivities for polyunsaturated fatty acids (PUFA) hydroxylation. Catalyzes the epoxidation of double bonds of certain PUFA. Converts arachidonic acid toward epoxyeicosatrienoic acid (EET) regioisomers, 8,9-, 11,12-, and 14,15-EET, that function as lipid mediators in the vascular system. Displays an absolute stereoselectivity in the epoxidation of eicosapentaenoic acid (EPA) producing the 17(R),18(S) enantiomer. May play an important role in all-trans retinoic acid biosynthesis in extrahepatic tissues. Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid. May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSYDAYQMRPGQGRDYARQQRQQRSYQLSDDPLRQPGAPYANPAGGYPSSASMNPENPFYAAENPSFQTLAPATSEGHATYTYEEDKIPLTDSADEKYGFSQNGHSTYNLASQSGFPPSTPCGGPSSYSSALGPEDSASQVAWAKRQQAPKRGLTKKIQLTRGHWIVDHPVPTAVKNSVESRWSQGNRTQEFTHMRYTAATCDPDEFTLENGWSLRTSQQYGRDTELLIAITYYNEDRILLARTLHGVMLNIRDICKSKSSKFWRRSAEEGRPGWQRIVVSLIFDGIDPCDKEVLDLLATVGVYQDGVMKRKVDGKDTVAHLFEYTTQLSVDPTPALIQPHADDASNLVPVQMIFCLKQKNSKKINSHRWLFNALGRHLQPELCVLIDAGTKPGHKSLYYLWEAFYNNANLGGACGEIHAMIKNGRKLINPLVAAQNFEYKMSNILDKPLESTFGYVSVLPGAFSAYRFRAIQGRPLQQYFHGDHTLADRLGKKGLHGMDIFTKNMFLAEDRILCFELVAKAGDKWTLTYVKPSKGETDVPEGAAELISQRRRWLNGSFAASIYSLVHFFRIYKSNHGIIRLFFLHIQALYNAIVLLFSWFALANLWLTFSIIIEFLPDELLKNSSHTTLVVFHWINQAAKWIYVFFLVLQFVLALGNRPKGEKPTYIASFIVFGILGLYLIFVSLWLTLKALLETSVSGNIWHTLFNQTTGVLIAALAATFGIYLIASILYADPWHMVTSFPQYMMIAPSFINILNVYAFCNLHDVSWGTKGSDKADALPTVDTKKDKSTEPGTVEEIERHQDDIDETFKAVVSRAVAPFKPAETVEKPTMDDSNKTFRTRLVAFWLLTNGALTVAIENVNGLNTGLTNKQIEQQQSSKQSTYFRIILWATFGLSAFRFIGCLIYWVKRNSTRCFRKT",
    "output": "Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKKLSKRMAALSTKIEDRIYPPLEALSIIKENANAKFDETIEAHIRLGIDPKYTDQQLRTTVALPHGTGQSIKIAVITSGENVSKAKSAGADLFGEEDLVESINKGNMDFDLLIATPDMMPKVAKLGRVLGPRGLMPNPKAGTVTNDIANAIKEFKAGKLEFRADKAGIVHVRFGKASFTKEALFDNLKTLQESIDKNKPSGSKGKYWKSFYVTSTMGPSVQVDISAVQDYQPEG",
    "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTSTPITYKTLADSIFNDLINNIIKQHTLTSLTNIKDHSSLLNSSNSNTNSNTNGTIASNGGNGTTSDENNEIENSTIQDKSKLKQLETSRYFRCLNCGRNIAGGRFASHISKCLERKRK",
    "output": "Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Involved in transcriptional regulation of a subset of SAGA-regulated genes. Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTPMSENNGSENTRDVSAAMMKSRSNSSEYAGGDGSFHASEVESQSSQGASGGNTSASKRRTKASRACDQCRKRKIRCDYDDDKGVCTSCRKNGESCAFERIQLKRGPSKGAVRGHSVSRSISGENNNTAATAVGSGGEFSSPSSRQGSVLLPPLGQYLPQPAPVPSNLNATQQQQFWKVPYHDFQGQRRGSIDSLSSDMSAKSVNIPQEHLLYASPSAGHPPLHSPVTFGPNNSSTDSGYWPFRNSGGEESDELRRKSGSNPPSLKNVSQPPPPPLQQQQQQQYSYSKFNNSFAQYGANGFPSRHGSIASEGMSPSASVPYQSVPMNQSNSNGLSQQQQQPIQWPKVQPKNLPPPQVQVQAADKEETLGNSFQKTIKKRRTVSASSGENKAEPGEYPLARFSSSGNDSLLGGNLVSPAGFVYGQIPEIQLIDIYYEFIHMVFPIIPLNKETVTNEILLVNTQPISPIHEINNYVILWFRNSLELLIRITLKRRSGHFYDSLTHSKERELSNEIRGNSNGGGSNDSKDDNLEMQGVFVTALNECLQKIVDIHPSFRENKDKISPKVKIIYLSTFVLLNYILAVVGYDNSFVLGMSTTIFKDFKVYELLLYDDEDDDATKSGSNDNDNTNNDNNSNNANNDNNDSRFYDENNAMNWDQAGYSITFKRLYVLLIIFDSLQCCSYGGPKLLNVPIEGASERFFQTKPHSNSKWVVDQSPTRMKFILQSVKFGELLAECSMKRRSICDLSRTQLTWEIPPYFLKGVTDEDDELFSLAQLLAAFILIRKEFVDCLLNLQDLETGELPTVDMELCGELIKLLCQLTSIILQALTVMMRTNPKNHIDYNYRPMKPMEHDDSGNSASRKFTTSQAESGKNSGNDFYHKLLGLQDNAEACLTNLLRGSISPYCISMLREIRNVMELVKKMPASLIGVVMACAGTHHNTANNNNNDPLAITFQSQELVVKLSNCMNDMMQITSLLNMIKPVNLSDQDSDNTSATATITTTETISKSLNRDHSIMRRLYYSKAAKRDKKHIYPSSSSSPQLQETITTLKSFVLIGWKLLDDFELGWS",
    "output": "Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose. In the absence of glucose, it functions as a transcriptional repressor, whereas high concentrations of glucose cause it to function as a transcriptional activator. In cells growing on low levels of glucose, has a neutral role, neither repressing nor activating transcription (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKKAPAGSFPAKPTIAPERPILVFDSGIGGLTVLREARVVMPDRRFVYIADDAGFPYGNWEEEALKRRIIELFGEFIANYDPEIAVIACNTASTLVLEDLRRAYPSVPFVGTVPAIKPAAERTSSGLVSVLATPGTVKRAYTRDLIQSFASRCHVRLVGADGLAAIAEAHIRGESFDEALVMAQIAPCFIEKDGKRTDIVVLACTHYPFLVNVLRRLAPWPVDWLDPAEAIARRMKSLLPARSDDDEFHSQDDLAFFTSRKPDYAIRRLMQGFGLRF",
    "output": "Provides the (R)-glutamate required for cell wall biosynthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKSTKILILGAGPAGFSAAKAALGKCDDITMINSEKYLPYYRPRLNEIIAKNKSIDDILIKKNDWYEKNNIKVITSEFATSIDPNNKLVTLKSGEKIKYEKLIIASGSIANKIKVPHADEIFSLYSYDDALKIKDECKNKGKAFIIGGGILGIELAQAIIDSGTPASIGIILEYPLERQLDRDGGLFLKDKLDRLGIKIYTNSNFEEMGDLIRSSCVITAVGVKPNLDFIKDTEIASKRGILVNDHMETSIKDIYACGDVAEFYGKNPGLINIANKQGEVAGLNACGEDASYSEIIPSPILKVSGISIISCGDIENNKPSKVFRSTQEDKYIVCMLKENKIDAAAVIGDVSLGTKLKKAIDSSKSFDNISSLDAILNNL",
    "output": "Catalyzes the NADH-dependent reduction of rubredoxin (Rd). NADPH is a very poor electron donor compared to NADH. Functions as an intermediate component in the electron transfer chain: NADH->NROR->Rd->FprA1/2. Also functions as an intermediate component in the electron transfer chains from NADH to revRbr and Dfx. Therefore, is a key electron carrier in an efficient multienzyme complex that can scavenge O(2) and reactive oxygen species (ROS), and thus plays an important role in the oxidative stress defense system in C.acetobutylicum, an obligate anaerobic bacterium."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKEDSFEMEGTVVDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVRVELTPYDLSKGRITYRAR",
    "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLMNRFVLKRVRQGKPLNKPRLSIFCSHKHIYAQIIDDMVGRTLVSASTYHYKQGWHSTMKDAQEVGQKLAQQALEKGIQQVVLDRGSYRYHGKIRALAEAARKEGLKI",
    "output": "Binds 5S rRNA, forms part of the central protuberance of the 50S subunit."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRRESEKQNYLSEHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVKVQKSSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES",
    "output": "Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKLRPLHDRVIIKRTEVEAKSAGGIVLTGSAAEKSTRGEIVAVGKGRILDNGEVRALDVKAGDKVLFNEGYGVKTEKIDGEEYLIMSESDILAVEE",
    "output": "Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRKLRQTGTTIAGGQTLFQSPEEGWQLYTSAQAPDGKCVCTAVIPAQSTCARDGRSRELRQLMEKVQNVSQSMEVLELRTFRDLQYVRSMETLMRSLDARLRAADGSVSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGNLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSNPITIRAMGSRFGSWMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHFRSRSVLVQRSLPGAGYNNTFPYSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVVRSWDTGYPKRSAGEAFMICGVLYVTNSHLAGAKVYFAYFTNTSSYEYTDVPFHNQYSHISMLDYNPRERALYTWNNGHQVLYNVTLFHVISTAGDP",
    "output": "Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation (By similarity). TGF-beta induces expression and nuclear translocation of OLFM2 where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes (By similarity). Plays a role in AMPAR complex organization . Is a regulator of vascular smooth-muscle cell (SMC) phenotypic switching, that acts by promoting RUNX2 and inhibiting MYOCD binding to SRF. SMC phenotypic switching is the process through which vascular SMCs undergo transition between a quiescent contractile phenotype and a proliferative synthetic phenotype in response to pathological stimuli. SMC phenotypic plasticity is essential for vascular development and remodeling (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSESQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAMGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNSIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQPGLFTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMGTKLQAADVACRAGIDTIIAAGNRPDVIGHAMEGLPVGTCFHAQESPLENRKRWIFGAPPAGELTVDAGATQAILERGSSLLPKGIKIVSGNFSRGEVIRIRNSEGRDIAHGVSRYNSDALRLIAGQHSQQIDAILGYEYGPVAVHRDDMIIR",
    "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQAGNNGGAKLKNDEFDNLYQKNINRRETETVIRRSIPVQRDLTGKILPNQVAYYEEIEREVTFGATHHILDKDNFDSYIYPTNFEVREYQFNIVQKSLYQNTLCAIPTGMGKTFIASTVMLNFFRWSKNGKIIFTAPTRPLVAQQIKACLGITGIPHDQAAILLDKSRKNREDIWTQKRVFFTTPQVIENDLKRGVLNPKDIICLVFDEAHRATGSYAYTNVVKFIDRFNSSYRILALTATPGTDIASVQEVVNNLNISNIEIRTEESMDIIRYMKKRYKEKIEIGLTTEIEMIIEQLGIAVKPVLQQAVELGIYDECHPSQINSFVAMQKSQQIIANPTIAEGIKWRNFFILQLLNHVGQMLKRIKIYGIRSFYGYFRNKFSEFTTKYNMGKSTNKIAASFYYHPILKILMKNCDVYTSNSSFIGHDKLQKIINELSDFFLNSRLDSRVIIFTELRESALEIVKTIDNMGSSSIRPHIFIGQARGKENFDDEGFIRKNKPKGRKKADRLKRLEEDKQKQLSKAKQKEQEKVERSSRRTGSSEEAQISGMNQKQQKEVISKFKNGDYNVLVCTSIGEEGLDIGEVDMIICFDTTGSPIKNIQRMGRTGRKRDGKILLLFSGNESRKFEKAMEDYYDLQRLIGQNFVEYKKSDRILPSNITPECRKEFIHISAENNELNNMEDSDEVIRYATQCMLGKVPKSKKSKAKAAKEPKGKSKTFFMPDNVETGIVSAIALVNKKKSNSNESETVIKTECFPNLDDIEKDMLASLSSPVKPEVDDYKDGTFQKTDRFEEKITGSNLKDMLMSFSKRDEESKVTSFSSDGNYVNEPFGNISLGEKLDINDDFASTPIVKADMNIGQYDRSLIENNSRGGVLFKNAFEKEEGLLKKSEKVYFRDHYSIDNTVVIEPIPNFKRYNKSCLINHNPQVENILNLFKGINENKTQITIEMNRSRCIARGIEKGSIQLTGSDFSLANVMVAQKNNEADIVWDTSKTNKNSHENLNELLDSDSDF",
    "output": "ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIVAVIHTEKERESAEPEELIEPFLTRFVGKVQGKNDRLSIVPDHPLLKDAIPCRAARGVQHEFKEGDWAVAEMRRHPLKGDRSFYADLTQYITFADDHFVPWWVTLARHNLEKEAPNGVATEMLDEGLERQDLTALNFVTIDSASTEDMDDALYAEELADGRLQLTVAIADPTAWIAEGSKLDNTAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPALACRMIIAADGTIDDDIAFFAATIESKAKLAYDNVSDWLENNGTWQPENEDIAQQIRLLHRICLSRSEWRHHHALVFKDRPDYRFVLGEKGEVLDIVAEPRRIANRIVEESMIAANLCAARVLRDKLGFGIYNVHTGFDPANADALAALLKTHGLHVDAEEVLTLEGFCKLRRELDAQPSGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGEAIARPQEDITQQMAERRRLNRMAERDVGDWLYARFLNDKAGTNTRFAAEIIDVSRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPAA",
    "output": "Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKKVEKVVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTQEQAGLIIPVEISVYEDRSFTFITKTPPAPVLLKKAAGVEKGSGEPNKTKVATVTKDQVREIAQTKMQDLNAADEEAAMRIIEGTARSMGITVQ",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSLLGTINPNINPERTVAGRGTQEEEGEIARVEHNHHNNAASVSTDETVLERSKEIGDEDVAVEEVTRLARQLTRQSTRFSTSGNVENPFLETKEDSTLNPLSPNFKAKNWMKNLLALSSRDPERYPKRVAGVAFKNLSVHGYGSPTDYQKDVFNSVLEVGTLVRRIMGTGKQKIQILRDFDGLVKSGEMLVVLGRPGSGCSTFLKTISGEMNGIYMDEKSYLNYQGISSKQMRKQFRGEAIYTAETDVHFPQLTVGDTLKFAALARAPRNRLPGVSREQYAVHMRDVVMAMLGLTHTMNTRVGNDFVRGVSGGERKRVSIAEATLSGSPLQCWDNSTRGLDSANALEFCKTLNLMTKYAGATVAVAIYQASQSAYDVFDKVTVLYEGRQIYFGRTDEAKEFFTNMGFECPERQTTADFLTSLTSPAERVVKPGFEGKVPQTPDEFVRAWKSSEAYAKLMREIEEYDREFPIGGESLNQFIESRRAMQAKNQRVKSPYTISVWQQIELCMIRGFQRLKGDSSLTMSQLIGNFIMALVIGSVFYNLPDDTSSFYARGALLFFAVLLNAFSSALEILTLYAQRPIVEKQARYAMYHPFAEAIASMLCDMPYKITNAIIFNLTLYFMTNLRREPGAFFVFLLFSFVTTLTMSMLFRTMAASSRTLSQALVPAAILILGLVIYTGFTIPTRNMLGWSRWMNYIDPIAYGFESLMVNEFHNRQFLCPDSAFVPSSGAYDSQPLAYRVCSTVGSVSGSRYVQGDDYLNQSFQYYKSHQWRNLGIMFGFMFFFMFTYLTATEYISESKSKGEVLLFRRGHAQPTGSHDVEKSPEVSSAAKTDEASSKEATGAIQRQEAIFQWKDVCYDIKIKGEPRRILDHVDGWVKPGTCTALMGVSGAGKTTLLDVLATRVTMGVVSGEMLVDGRPRDQSFQRKTGYVQQQDLHLHTTTVREALRFSALLRQPAHVPRQEKIDYVEEVIKLLGMESYADAVVGVPGEGLNVEQRKRLTIGVELAAKPQLLLFLDEPTSGLDSQTSWSILDLIDTLTKHGQAILCTIHQPSAMLFQRFDRLLFLAKGGKTVYFGEIGEKSSTLASYFERNGAPKLPPDANPAEWMLEVIGAAPGSHSDIDWPAVWRDSPERRAVHEHLDELKRTLSQKPIDPSKADPGSYDEFAAPFTIQLWECLLRVFSQYWRTPVYIYSKTALCVLTALYIGFSFFNAQNSAQGLQNQMFSIFMLMTIFGNLVQQIMPNFCTQRSLYEVRERPSKTYSWKAFMAANIIVELPWNTLMAFLIFVCWYYPIGLYRNAEPTDSVHERGALMFLLIWSFLLFTSTFAHMMIAGIELAETGGNLANLLFSLCLIFCGVLAPPQSLPGFWIFMYRVSPFTYLVSAMLSTGVSGTNAVCEPVEFLHFDPPSNMTCKDYMADYISTRGGYLENPSATSDCTFCTISSTDTFLSAVSSHYSDAWRNFGIMWAYIIFNIFAAVFIYWLARVPKGKRTKGST",
    "output": "Pleiotropic ABC efflux transporter that shows a strong substrate specificity for the azole class of drugs such as lotrimazole (CLT), fluconazole (FLC), itraconazole (ITC), ketoconazole (KTC), posaconazole (POS), tebuconazole (TEBZ), and voriconazole (VRC) (Probable) . Is also able to transport rhodamine 6G (R-6G), a known substrate for many ABC transporters . Required for normal pathogenesis in a Galleria mellonella (greater wax moth) infection model ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKAVVFAYHDMGCTGIQALLDAGYDIAAIFTHPDNPGENHFFGSVARLAAEQGIPVWAPEDVNHPLWIERIREMKPDVLFSFYYRNLLGDEILNLAPKGAFNLHGSLLPKYRGRAPLNWVLVNGESETGVTLHRMVNRADAGDIVAQQAVAIGADDAALTLHRKLCAAATELLSRALPAILAGTTDERPQDHSQATYVGRRTPEDGRLDWELPAQTLHNLVRAVSDPWPGAFGYAGANKFIVWKSRVRHDLPAAKPGTVLSIAPLIVACQDGALEIVTGQTERGVYMQGAQLAQALGLVSGAVISSKPVVAIKRRTRVLILGVNGFIGNHLTERLLQDDNYEIYGLDIGSDAISRFLDCPRFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLKIIRDCVKYNKRIIFPSTSEVYGMCTDKNFDEDSSNLVVGPINKQRWIYSVSKQLLDRVIWAYGDKNGLKFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIEGGKQKRCFTDISDGIEALFRIIENKDGRCDGQIINIGNPDNEASIKELAEMLLACFERHPLRDRFPPFAGFREVESSDYYGKGYQDVEHRKPSIRNAKRCLNWEPKVEMEETVEHTLDFFLRTVELVDDKNP",
    "output": "Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSNPTSTPRADGFRMPAEWEPHEQTWMVWPERPDNWRNGGKPAQAAFAAVAKAIARFEPVTVCASAGQYENARARLDDGNIRVVEISSDDAWVRDTGPTFVIDDKGDVRGVDWGFNAWGGFEGGLYFPWQRDDQVARKILEIERRARYRTDDFVLEGGSIHVDGEGTLITTEECLLNHNRNPHLSQVEIERTLRDYLAVDSIIWLPNGLYNDETDGHVDNFCCYVRPGEVLLAWTDDQDDPNYLRCQAALRVLEESRDAKGRKLVVHKMPIPGPLYATQEECDGVDIVEGSQPRDPSIRLAGSYVNFLIVNGGIVAPSFDDPKDAEARAILQRVFPEHEVVMVPGREILLGGGNIHCITQQQPAPRKA",
    "output": "Mediates the hydrolysis of agmatine into N-carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHFSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHANIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAATPQFIIGPGGVVNLTDETGVSAVQFGNSSTSVLATLAALAEASAPLSNSSETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGMGQPIIVTMPDGQQVLTVPATDIAEETVISEEPPAKRQCMEIIESRVECAEIEEREALQKQLDEANREAQKYRQQLLKKEQEAEAYRQKLEAMTRIQTNKEAV",
    "output": "Transcription factor capable of interacting with purine rich repeats (GA repeats) . Acts as a a master regulator of nuclear-encoded mitochondrial genes ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSPSAVDDAPKATGAAISVKPNIGVFTNPKHDLWISEAEPSADAVKSGADLKPGEVTIAVRSTGICGSDVHFWHAGCIGPMIVEGDHILGHESAGEVIAVHPTVSSLQIGDRVAIEPNIICNACEPCLTGRYNGCEKVEFLSTPPVPGLLRRYVNHPAVWCHKIGNMSWENGALLEPLSVALAGMQRAKVQLGDPVLVCGAGPIGLVSMLCAAAAGACPLVITDISESRLAFAKEICPRVTTHRIEIGKSAEETAKSIVSSFGGVEPAVTLECTGVESSIAAAIWASKFGGKVFVIGVGKNEISIPFMRASVREVDIQLQYRYSNTWPRAIRLIESGVIDLSKFVTHRFPLEDAVKAFETSADPKSGAIKVMIQSLD",
    "output": "Catalyzes the NAD-dependent oxidation of L-arabinitol to L-xylulose in the fungal L-arabinose catabolic pathway. L-arabinose catabolism is important for using plant material as a carbon source. Can partially compensate for xylitol dehydrogenase in xdh1 mutants. Also oxidizes galactitol to L-xylo-3-hexulose as an alternative to the standard Leloir pathway for D-galactose metabolism. NADP cannot act as a cosubstrate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEKDTSIPEDLKLAVLEKIKPTEAERKILTAVQEELAAEVKAAAEKLCVADIFVKMVGSAARGTWLSGTHDIDVFISFPEETSREELERRGMEIAREVAKKAEHAEDRHAEHPYLNIVFKGFDVDLVPCFRVESACQLKSAVDRTPFHNEFVKTHIKGREDDVLLMKQFMRGGGVYGSELKTQGFSGYLTELLIIHYGSFENTVKAACLWKPGKKIDIMQHSEMEHTEPLVMVDPTDPKRNVAAALSLDKFCMFMDHCREFMKSPGLNFFFPPPLSPLEDREFLEKLESRKSSQLAIVFKTPDIVDDVLYPQLYKMEQAAAALLHEYDFSVIKTGVWSGKPETVVMLELISGTLPNVKKRIGPPVWVREHAEKFKAKYEGAENVFGGYIEGGKYVFEIQRKYPTAKGLLENQLLNCSLGKQVKSSVSAGFEVIEDAEICRLKDPDFRVFLRKWV",
    "output": "Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASQVMRITLKAYDHELVDSSAKKIIETVKKNGSQVSGPVPLPTKKEVVTILRATHKYKDSREQFEQRTHKRLIDIINPTQKTTESLSRIEMPAGVYIDIKMKQK",
    "output": "Involved in the binding of tRNA to the ribosomes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNNLFPFLALNKIALQLGPLAIHWYAIFIVGGAALAVWLACKEAPKRNIKTDDIIDFVLFAFPLGIVGARLYYVIFQWSYYSQHPSQIIAMWDGGGAIYGSLIAGAIVLFVFSYYRMIHPLDLLDITIPGVFLAQAMGRWGNFVNQEAYGKIVSNLDWLPAFIRNQMFIDGHYRMPTFLFESIGTLSGFILVMVFRHRIKGLKRGDIFSFYLVWYGAVRFIVEGMRTDSLMLGPARVSQWLSVLLVIVGLVLFIYRRMKKN",
    "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADAWEEIRRLAADFQRAQFAEATQRLSERNCIEIVNKLIAQKQLEVVHTLDGKEYITPAQISKEMRDELHVRGGRVNIVDLQQVINVDLIHIENRIGDIIKSEKHVQLVLGQLIDENYLDRLAEEVNDKLQESGQVTISELCKTYDLPGNFLTQALTQRLGRIISGHIDLDNRGVIFTEAFVARHKARIRGLFSAITRPTAVNSLISKYGFQEQLLYSVLEELVNSGRLRGTVVGGRQDKAVFVPDIYSRTQSTWVDSFFRQNGYLEFDALSRLGIPDAVSYIKKRYKTTQLLFLKAACVGQGLVDQVEASVEEAISSGTWVDIAPLLPTSLSVEDAAILLQQVMRAFSKQASTVVFSDTVVVSEKFINDCTELFRELMHQKAEKEMKNNPVHLITEEDLKQISTLESVSTSKKDKKDERRRKATEGSGSMRGGGGGNAREYKIKKVKKKGRKDDDSDDESQSSHTGKKKPEISFMFQDEIEDFLRKHIQDAPEEFISELAEYLIKPLNKTYLEVVRSVFMSSTTSASGTGRKRTIKDLQEEVSNLYNNIRLFEKGMKFFADDTQAALTKHLLKSVCTDITNLIFNFLASDLMMAVDDPAAITSEIRKKILSKLSEETKVALTKLHNSLNEKSIEDFISCLDSAAEACDIMVKRGDKKRERQILFQHRQALAEQLKVTEDPALILHLTSVLLFQFSTHSMLHAPGRCVPQIIAFLNSKIPEDQHALLVKYQGLVVKQLVSQSKKTGQGDYPLNNELDKEQEDVASTTRKELQELSSSIKDLVLKSRKSSVTEE",
    "output": "E3 protein ligase that mediates ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to lysine residues on target proteins, and which plays a key role in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress . In response to endoplasmic reticulum stress, recruited to the endoplasmic reticulum membrane by DDRGK1, and mediates ufmylation of proteins such as RPN1 and RPL26/uL24, thereby promoting reticulophagy of endoplasmic reticulum sheets . Ufmylation-dependent reticulophagy inhibits the unfolded protein response (UPR) via ERN1/IRE1-alpha . Ufmylation in response to endoplasmic reticulum stress is essential for processes such as hematopoiesis, blood vessel morphogenesis or inflammatory response . Regulates inflammation in response to endoplasmic reticulum stress by promoting reticulophagy, leading to inhibit the activity of the NF-kappa-B transcription factor (By similarity). Mediates ufmylation of DDRGK1 and CDK5RAP3; the role of these modifications is however unclear: as both DDRGK1 and CDK5RAP3 act as substrate adapters for ufmylation, it is uncertain whether ufmylation of these proteins is a collateral effect or is required for ufmylation . Catalyzes ufmylation of various subunits of the ribosomal complex or associated components, such as RPS3/uS3, RPS20/uS10, RPL10/uL16, RPL26/uL24 and EIF6 (By similarity). Anchors CDK5RAP3 in the cytoplasm, preventing its translocation to the nucleus which allows expression of the CCND1 cyclin and progression of cells through the G1/S transition . Also involved in the response to DNA damage: recruited to double-strand break sites following DNA damage and mediates monoufmylation of histone H4 . Catalyzes ufmylation of TRIP4, thereby playing a role in nuclear receptor-mediated transcription . Required for hematopoietic stem cell function and hematopoiesis (By similarity). Required for cardiac homeostasis (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEYDLTKQICSFLDAHMMLPLINYLKDTQQYQENEINKAMADILSQTGCCDYAINAYESIGRDTAPLQAKKQELVGELNKLKEQCSFVTQYIESKKQQKEQQKELKEQQKEQQKEKDTDKTTPTTTDETTTTTTTAPTTTTTTTTTTITPITVIPFSQLLEKITPEILDSIYRFSKLLFEIGQYGSAREHLEIFLQLSPTHQNKDKRLSALWGILESDILSLNWGQAVGDISPLQDQIDSNGTPVEQLGQRAWLIHRALFVYFYNPESRSSLVDLLLEDKYLNAIQTTCPHILRYLAVAIIVNKKKQQSNVFQRILNALVRVVEQEAYVYRDPITQFISSLFVKFNFEDAQAQLILCEKVLKNDFFLNTCVDEFMENARVCVFETYCNILESIDIDMLCKNLRIDPESSEKWIVEAIRNTRFSAKIDSANNQIKMFTQHNSYRQVMDKTKALFNRGIEMVVGINESRSQQNRKGGDNRKNQRGQNRNQQNQQNQQSNESNETTTTTTTAAAATTTTTTTATPTSA",
    "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLARSVRTLVVSPKTVFRFRGCLFEKHVSTASADDRAIVSLFDSPHAAFKYPSTISTGLFGHSQLSHPNAFISLAEATLVRAQLLTDRILRARSSRDELLKVVKNLDRLSDMLCSVIDLAELIRNAHPDRNWATAGHHVYEQLCEFMNVLNTHVGLYEVLKLVLADASIVKTLSPEAYQTALIFWRDFEKSAINLPPEERQKFVSLSSDILVLGREFLENANAPRPPASIKPEHMVGIKDKGLGVRLQLQAQFTRRDLLVYPGSLQAQMIMRSAPDEEPRRRMYIAANSSTDQQIXTLERLLKTRAELARLVGRSSFAHMTLDDKMAKTPENVMNFLGALIGQTRPFARRALKTLSARKQAHHGLSSLPTIQAWDRDFYCPPEPPAPPIPLPPLTLGTIFMGLSRLFKYLYGITLRPTEAQTGEVWHSDVHKLEVIDEDKGLIGWIYADLFARHGKSSGAAHYTVRCSRRTDLDDDLGDGGLTGHEELIQQNLEFEKVKRHKIPNQDGVYQLPLVVLLCEFTRPSVLKGATVLEWHDVMTLFHEMGHAMLAMVGRTEYQNVSGTRCATDFVELPSILMEHFLSSPVVLSLFDLDGTHSLRQVGNTHEDPCHSIDTFSQIILASLDQIYHSPAVLDNSTFSTTDELENLTVSKGVIPHVPSTSFQTQFGHLFGYGATYYSYLFDRAIASRVWKKVFEKDPLKREVGEKYKLEVLRWGGGRDPWKMVSKLLDASELEKGDAEAMREVGRWRIEDEVGLPGRH",
    "output": "Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASIDPYQHIIVEHQYSHRFTVTVIKATNVTKGTFGDMLDTPDPYVELYISSAPDSRKRTKHFNNNINPVWNETFEFILDPNQDNVLEITLMDANYVMDESLGTTTFPILSVKPGEKKQVPFTFNKVTEMILEFSLEVCSSTDLRFSMALCDQEKLFRQKRKNKVINGLRKLLGPEKTQDLNSTSRDVPVIAVLGSGGGFRAMIGFSGVMKALYESGVLDCATYVAGLSGSTWYMSTLYSHPDFPTKGPKEINKELMHNVSYNPLLLLTPQKVKRYVEALWKKKSSGQPVTFTDIFAMLIGETLIKDRMNRKLSHMQEKINDGQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMPPGLFGSKFFMGTVIKKYEENPLHFFMGVWGSAFSILINRVLGVSNNSKGSTMEEEIENLKPKHILGNDSSDSDDEMQEPKGTENAKAEEEYLRNNQASWVQRMLMAILGDSAIFNTREGRAGKVHNFMLGLNLNTSYPYSPLSGLCTQQSMEEDELDAAVADPDEFEQIYEPLDVKSKKIHIVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWARMNKLPFPKIDPHVFDREGLKECYIFKPKNTSVEKDCPTVIHFVLANLQFRNFKAPGVPRETTEEKESADFDIFDDPETPFSTFNFQYPNVAFKQLHDLMEFNTLNNINVIKQAMVESIEYRRQHPSRCSVSLNDVESRKLHHKDSQSKFQM",
    "output": "Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "RPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSMRYPLVDGQGNFGSPGNDPPAAMRYCITGDALVALPEGESVRIADIVPGARPNSDNAIDLKVLDRHGNPVLADRLFHSGEHPVYTVRTVEGLRVTGTANHPLLCLVDVAGVPTLLWKLIDEIKPGDYAVIQRSAFSVDCAGFARGKPEFAPTTYTVGVPGLVRFLEAHHRDPDAQAIADELTDGRFYYAKVASVTDAGVQPVYSLRVDTADHAFITNGFVSHNTEAPLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHN",
    "output": "A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVEVGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTDYFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFEYSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF",
    "output": "Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSPSLTWHDVIGQEKEQPYFKDTLAYVAAERRAGKTIYPPQKDIFNAFRLTELDQVKVVILGQDPYHGPNQAHGLSFSVLPGVPAPPSLGNIYKELVTDIPGFQRPNHGFLQSWAEQGVLLLNTVLTVEAGKAHSHANLGWETFTDRVIAALNEHREGVIFMLWGSHAQKKGRIINTERHYILKAPHPSPLSAHRGFLGCKHFSQANQLLQQQNQQPIDWQPKLPAVE",
    "output": "Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAQRNGMSPRPPPLGRGRGAGGPSGVGSSPPSSCVPMGATSTAGTGASAAPTATPGHGVHRVEPRGPPGAPPSSGNNSNFWHGPERLLLSQIPVERQALTELEYQAMGAVWRAAFLANSTGRAMRKWSQRDAGTLLPLGRPYGFYARVTPRSQMNGVGATDLRQLSPRDAWIVLVATVVHEVDPAADPTVGDKAGHPEGLCAQDGLYLALGAGFRVFVYDLANNTLILAARDADEWFRHGAGEVVRLYRCNRLGVGTPRATLLPQPALRQTLLRAEEATALGRELRRRWAGTTVALQTPGRRLQPMVLLGAWQELAQYEPFASAPHPASLLTAVRRHLNQRLCCGWLALGAVLPARWLGCAAGPATGTTSPPAASGTETEAAGGDAPCAMAGAVGSAVTIPPQPYGGAGGSAICVPNADAHAVVGADATAAAAAAAAAPTVMVGPTAMAGPAASGTVPRAMLVVVLDELGAVFGYCPLDGHVYPLAAELSHFLRAGVLGALALGRESAPAAEAARRLLPELDREQWERPRWDALHLHPRAALWAREPHGQLAFLLRPGRGEAEVLTLATKHPVICANVEDYLQDARRRADAQALGLDLATVVMEAGGQMIHKKTKKPKGKEDESVMKGKHSRYTRPTEPPLTPQASLGRALRRDDEDWKPSRVPGEDSWYDLDETFWVLGSNRKNDVYQRRWKKTVLRCGLEIDRPMPTVPKGCRPQTFTHEGIQLMGGATQEPLDTGLYAPSHVTSAFVPSVYMPPTVPYPDPAARLCRDMRRVTFSNVATHYHYNA",
    "output": "Inhibits the establishment of the antiviral state in the infected cell. Prevents the phosphorylation of the host eukaryotic translation initiation factor eIF-2alpha/EIF2S1 and thus the shutoff of viral and cellular protein synthesis by directly interacting with EIF2AK2/PKR. Also inhibits host autophagy by interacting with host Beclin-1/BECN1 (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLDLAFVRANLELVEARLRARGQNPAELLGDFAAVDQHRRERITEAEQLKATRNKLSEEVARLRKAKEDASAVMEETRQLKTKIEDLERAATEAEEQLRERMARIPNLPYEDVPTGASAEDNVEVKRWGTPREFDFAPKPHWELGEQLGILDFERAAKLSGARFAVYWAEGARLERALAAFMLDLHTREHGYTEVLPPLMVNSRSLFGTGQLPKFAEDLFRCEDGEPYQAGKYRENDHWLIPTAEVPLTNLFRDETLDDSQLSTSLVAHTSCFRSEAGSYGKDVRGIIRQHQFQKVELVKFTRPEDSAAEHEALTRHAETVLERLGLPYRRMLLCTGDMGFSSAKTYDLEVWLPGQQVYREISSCSNFDAFQARRAGIRYRPRGQGKSAHVHTLNGSGLAIGRTWLAILENYQQADGSVRIPEALIPYMGTEVIESRNVAQGAK",
    "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDVLFSIAKTVSELKKRVVVGTIYTNVEDIIQQTNELIRTLNGSTFHTGGIGTQPQKDWVVQLPQLGTTLLNLDDNYVQSARGIIDYLASFIEAVCDDEMVREASRNGMQPQSPTLIALASSKFKTINFNNSSQSIKNWSAQSRRENPVYEYKNPMVFEYRNSYILHRADQQFGNAMGLRYYTTSNTCQIAAFDSTMAENAPNNTQRFIYHGRLKRPISNVLMKVERGAPNVNNPTILPDPTNQTTWLFNPVQVMNGTFTIEFYNNGQLVDMVRNMGIATVRTFDSYRITIDMIRPAAMTQYVQQLFPVGGPYSHQAAYMLTLSVLDATTESVLCDSHSVDYSIVANTRRDSAMPAGTVFQPGFPWEQTLSNYTVAQEDNLERLLLVASVKRMVM",
    "output": "Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTTEQTTMNITEIQELLPHRYPFLMVDRVTSFEKEKTLTAIKNVSVNEPQFTGHFPQLPVFPGVLILEAMAQATGLLAFKSFGAPSGNELYYFASVDKAKFRKPVVPGDQLVIEVEFLKERRGIASFNGVAKVDGVVVCSAELKCARREF",
    "output": "Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLFDKYGRSLQKLRYVVNDECNYNCVFCHFEGQSRRQGRYLTAEDYGFVTSVFKSLGVADFKITGGEPLLRGDIDLIVANIAKTGAYVTLTTNGYLLRKWVRKLQAAGLKRANVSIHTTDPEKYSKITGVPPSAFREVLRGLTEARDVGISLKLNAVVLRGINTDRDSVKNLVKLAASLGAALQFIELMPSGWGASVFNELYEPIETLVNIIFELGGRPAGVRKELHNRPLYNIAGVTVELIKNFSNPTFCSGCTTMRLTSDGKLKTCIYADSSVDLMPYIKSRDVEGLLYAVRTALARREPRFKLYSSS",
    "output": "Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSVVGTPKSAEQIQQEWDTNPRWKDVTRTYSAEDVVALQGSVVEEHTLARRGAEVLWEQLHDLEWVNALGALTGNMAVQQVRAGLKAIYLSGWQVAGDANLSGHTYPDQSLYPANSVPQVVRRINNALQRADQIAKIEGDTSVENWLAPIVADGEAGFGGALNVYELQKALIAAGVAGSHWEDQLASEKKCGHLGGKVLIPTQQHIRTLTSARLAADVADVPTVVIARTDAEAATLITSDVDERDQPFITGERTREGFYRTKNGIEPCIARAKAYAPFADLIWMETGTPDLEAARQFSEAVKAEYPDQMLAYNCSPSFNWKKHLDDATIAKFQKELAAMGFKFQFITLAGFHALNYSMFDLAYGYAQNQMSAYVELQEREFAAEERGYTATKHQREVGAGYFDRIATTVDPNSSTTALTGSTEEGQFH",
    "output": "Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates . It could also catalyze the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route) (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTVRVRLAPSPTGNLHIGTARTAVFNWLYARHRGGKFILRIEDTDRERSRPEYTENILEGLQWLGLTWDEGPYFQSDRLDLYRQAIQTLLDKGLAYYCYCTPEELEALRAEQKAKGQAPRYDNRHRHLTPEEQAAFEAAGRTPVIRFKIEDDRQIEWQDLVRGRVSWQGADLGGDMVIARAAPRGEIGYPLYNLVVVVDDIAMGITDVIRGEDHIGNTPKQILLYEALGATPPNFAHTPLILNSTGQKLSKRDGVTSISDFRAMGYLAPALANYMTLLGWSPPEGVGELFTLDLAAKHFSFERINKAGARFDWDKLNWLNRQYIQQLEPEEFLAELIPLWQGAGYAFDEERDRPWLFDLAQLLQPGLNTLREAIDQGAVFFIPSVTFDSEAMAQLGQPQSATILAYLLEHLPAEPALTVAMGQQLIQQAAKAAGVKKGATMRTLRAALTGAVHGPDLMAAWQILHQRGWDEPRLAAALKQAQTTS",
    "output": "Non-discriminating glutamyl-tRNA synthetase. Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). Acylates both tRNA(Glu) and tRNA(Gln) with glutamate, but has 13-fold higher efficiency with tRNA(Glu)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKQVVIASRESPLAMWQAEHIRARLQALYPGLEVSILGITTQGDRILDKTLNKIGGKGLFVKELELAMQEGQADLAVHSIKDVPMDLPEGFALAAICEREDPRDAFVSSRYASLSELPAGAVVGTASLRRESQIRARYPHLLVKPLRGNLQTRLRKLDEGQYDAIILAASGLKRMGLAERIRMELSTADSLPAVGQGALGIEIRADRTDLMALLAPLNHPATYACVTAERAMGRALGASCQIPVGGYAEQHEHMLVMRGFVATPDGTTLLHAEATAPAEYADALGRTIAKKLLDQGADDVIDAVKAAG",
    "output": "Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPNNVTVQELVDKVRLKVLQGEDYLQRKITTSDISRPALEFAGYFKHYPAARIQLLGITETSFAKDLTHEQREEYMTKMCMPQTPCFVISTNLPIPKELKKAAEDAKIPILGTHLTSSQILSNMTSYLLERLAPRKSLHGVLVDISGVGVLITGDSGVGKSETALELVRRGHRLIADDRVEVYARDEQTLVGTAPQILKHLMEIRGIGIIDVSTLYGTGAIMPSDQISLIVHLETWTPDVQFDRLGDRGDTQTIQGVIVPKVSVPVKTGRNLAIIIESAAMNYRAETMGYDATETFDRNLNQLIKQNSERDSKNNKGSAN",
    "output": "Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKSTFEAAGRVAKGMLKDPSKKYKPFKGIQLPNRQWPNKVLTKAPRWLSTDLRDGNQALPDPMNGQEKLRYFKLLCSIGFKEIEVGFPSASQTDFAFVRHLIETPGLIPDDVTISALTPSREPLILRTIEALRGAKNATVHLYNACSPLFREVVFRNSKQETLDLAIKGSKIVTAATKNALESKETNWGFEYSPETFSDTEPDFALEVCEAVKGMWKPSAAQPIIFNLPATVEMSTPNTYADLIEYFSTNISEREKVCVSLHPHNDRGTAVAAAELGQLAGGDRIEGCLFGNGERTGNVDLVTLAFNLYTQGVSPNLDFSKLDEIIRITEDCNKINVHPRHPYAGNLVFTAFSGSHQDAISKGLKAYDERKAVDPVWKVPYLPLDPHDVNSEYAAIIRVNSQSGKGGVAYLLKTNCGLDLPRALQVEFGSIVKDYSDTKGKELSIGEISDLFYTTYYLEFPGRFSVNDYTLSSNGPQSKCIKCVVDIKGEKKDTPSRVVIEGVGNGPLSALVDALRRQFNISFDIGQYSEHAIGSGNGVKAASYVEIIFNNTSFWGVGIDADVTSAGLKAVMSGVSRASRAFAK",
    "output": "Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDTITPLLAKADFEQRSRLQIIPAQSVIASNARPSQAIRASRGSSMRVALELVKEGRAQACVSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQFAIMGSVLAEEVVGIPNPRVALLNIGEEEVKGLDSIRDASAVLKTISSVNYIGYLEANELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKSLTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAARLKSVYPAGFELLEDERGKKPNHR",
    "output": "Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGENMIAADGTLQRRALRERIFANPEEKNWLNDLLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP",
    "output": "Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNKRAMLGAIGLAFGLLAAPIGASAKGESIVWNEQWKTPSFVSGSLLNGGEQALEELVYQYVDRENGTFRLGGRARDRLALIGKQTDELGHTVMRFEQRHHGIPVYGTMLAAHVKDGELIALSGSLIPNLDGQPRLKKAKTVTVQQAEAIAEQDVTETVTKERPTTENGERTRLVIYPTDGTARLAYEVNVRFLTPVPGNWVYIIDATDGAILNKFNQIDSRQPGGGQPVAGASTVGVGRGVLGDQKYINTTYSSYYGYYYLQDNTRGSGIFTYDGRNRTVLPGSLWTDGDNQFTASYDAAAVDAHYYAGVVYDYYKNVHGRLSYDGSNAAIRSTVHYGRGYNNAFWNGSQMVYGDGDGQTFLPFSGGIDVVGHELTHAVTDYTAGLVYQNESGAINEAMSDIFGTLVEFYANRNPDWEIGEDIYTPGVAGDALRSMSDPAKYGDPDHYSKRYTGTQDNGGVHTNSGIINKAAYLLSQGGVHYGVSVNGIGRDKMGKIFYRALVYYLTPTSNFSQLRAACVQAAADLYGSTSQEVNSVKQAFNAVGVY",
    "output": "Extracellular zinc metalloprotease."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTNAIDELQAIIAELKTEVEEQRAVIRQSRDRIEHMSAEVRMNIVKNYERIRDKTVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLFFTPDQAGLSKVEAAARTLTFINPDVRIETHNYNITTIDNFDNFLNTITGDGTVAGEPVDLVLSCVDNFEARMAINAACNEKCLNWFESGVSENAVSGHIQFLRPGDTACFACAPPLVVAENIDEKTLKREGVCAASLPTTMGITAGFLVQNALKYLLNFGEVSDYLGYNALNDFFPKMTLKPNPQCDDRNCLLRQKEFQARPKPVVVQEEAPTDEPLHASNDWGIELVAEDAPSNAPTDLSQSTDVGQGLRLAYEAPEKSSAEATQAATAPVDDTSLEDLMAQMKSM",
    "output": "E1-like enzyme which activates UFM1."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATAPATEKKAPAKKAAAPKAAAPKKAAAPKAAAPVGAATGRIAQVIGAVVDVQFTGELPAILNALETDNNGNRLVLEVAQHLGENTVRTIAMDATDGLTRGQPVRDTGAQISVPVGPQTLGRILNVIGEPIDERGPVNSDMTAPIHAKAPEFVDQSTEASILVTGIKVIDLIAPYAKGGKIGLFGGAGVGKTVLIQELINNIAKGHGGVSVFAGVGERTREGNDLYHEFLDAGVIAKDADGNPTPDGSKVALVFGQMNEPPGARARVALSGLTMAEYFRDQEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLSTDMGALQERITSTTKGSITSVQAIYVPADDLTDPAPATSFAHLDATTTLSRAISELGIYPAVDPLDSTSRVLTPAIVGQEHYETARRVQETLQKYKSLQDIIAILGMDELSEEDKLVVARARKIQRFLSQPFHVAEVFTGIPGKFVPIEETVKSFKAVVDGEYDHLPEAAFYMVGGIDEAVAKAAKLAEEA",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLDIQLLRTQLDTVAARLAARGYTLDTEAFTALENERKALQTRTQDLQARRNSLSKQVGEAKRRGEDASAVLAEVSGLGDELKANEAALEGLQGRLAELLQAIPNLPHESVPVGRDETGNVEIRRVGVPRSFDFQVKDHVDIGTPLGLDAETGAKLSGARFTVLRGQMARLHRALAQFMLNTHADEHGYTEVYTPYMVNATSMYGTGQLPKFEEDLFRVPRGDENFYLVPTAEVPVTNFVRDEIVKAADLPLRYVAHTPCFRSEAGAYGRDTRGMIRQHQFDKVELVQVVRPEESLNALETLTGHAETILKKLGLPYRVIVLCTGDMGFGSQKTYDIEVWLPAQDTYREISSCSSMGDFQARRMQARFKDEAGKNQLVHTLNGSGLAVGRTLVAVLENYQNADGSVTVPEVLRPYMGGLEKLLPQG",
    "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSNKKRSASSSRWLQEHFSDKYVIQAQKKGLRSRAWFKLDEIQQSDKLFKQGMTVVDLGAAPGGWSQYAVTQIGSKGRVIACDLLPMDPIVGVDFLQGDFRDELVLKALLERVGDKKVQVVMCDMAPNMSGTPAVDIPKSMYLVELALDMCRDVLAPGGSFLVKVFQGDGFDEYLREIRSLFTKVKIRKPDASRARSREVYIVATGRKL",
    "output": "Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "METLSFEFAAGQPARGKALVGVVGSGDLEVLLEPGQAGKLAIQVVTSVNGAEQRWQQLFERMFREQTPPALNIDIHDFGATPGVVRLRLEQGLEEVGHD",
    "output": "Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDIILLERIPRLGQMGDIVSVKDGYARNFLLPQGKALRANDANKKHFEKQRAQLKARNLERKSEAQKIAEKLDGKSFIVVRSAGETGQLYGSVSTRDISEIITSAGFSIGRNQIELNHPIKTIGLYLITLSLHPEVQISVVINVARSASEAQRQAEGETLTSAEAIYDIQEKPLAENQEEMNDNDANSINEQA",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPKAPKGKSAGREKKVIHPYSRKAAQITREAHKQEKKEKLKNEKALRLNLVGEKLQWFQNHLDPQKKRYSKKDACELIERYLNRFSSELEQIELHNSIRDRQGRRHCSRETVIKQTMERERQQFEGYGLEIPDILNASNLKTFREWDFDLKKLPNIKMRKICANDAIPKTCKRKTIITVDQDLGELELNDESSDSDEEMTAVA",
    "output": "Involved in the biogenesis of the 60S ribosomal subunit in the nucleus."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKLTCVVIVAVLFLTVWTFATADDSGNGLEKLFSNAHHEMKNPEASKLNERCLDAGEVCDIFFPTCCGYCILLFCA",
    "output": "Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQFSVLAGSLEKMESTAKRLELTGILEELLRETPHEVIAQIVYLIQGKLRPEFEGIELGVAEKLAVRAVSKSSGMPAARIEAAYRRDGDLGRAASSILEQKTQTTFLAEEITVERVYDTLMRIARLEGARSQDMKMRHISSLLNDASPRDACYILKLILGTLRLGIAENTVMDALAAAFTGSKSNRPELERAYNVSSDLGRVAEAVSSGGLEAVRGFAVAVFSPIRPMLADRVRSESEALEKMGAGLAAEYKLDGERVQVHLSGGRVELFSRSLENITAYYPDIVERIPGRLRAREAVLEAEAVAVNEETGEFLPFQELMHRRRKYDIDKAVMRYPITVNFFDILYLDGRDCLGISYSERRALLEGVVDEDSFARCVPVSTIPDESALEDSLENSINAGCEGLMLKLPDAPYRAGSRGGYWLKLKREYRNELGDSLDLVIIGAFFGKGRRTGRYGTLLLATYDDSRDTFPSICKVGTGFTDEDLDQLYQLLSPRVTLKRNPRIDSGMEADVWFDPEVVMEVVASEITLSPVHKTALDSVRKGAGLALRFPKFTGKLRTEKTAEDASTDQEVIALYKSQKKVVPDGQPGV",
    "output": "DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEPSKQEVPKLMETPPNISNDSSATEKGEATRQQQLPNNRYALTVDEVIEQHIGALGFAQILHALLVSIAWIFDAQTTLISIFSDAQPAARLLATGAIVEGASLCGLASGEWEWIGPKSDTVVSEWNLICQHKFLVAVPSTLFFIGSLFGSGVYGYLADSWFGRKKTLLLSCVLTFVTAFAISFSPNVWVYAFLRFANGFFRSGIGSCCIVLATEIVGKKWRGQVGQYGFFFFTLGFLSLPLMAYLERKSWRNLYRIISFLPLGYAVCLLPFAYESPRWLLVKGRNKEAMVVLKKLARLNGKQLPADLSLVDPIPERDDQTSSSEKFWKTKWAVKRIIMVMMAGFGSGFVYYGIQLNAENLNFNLYLTVAVNALMEFPAVFIGSFLLGVMNRRPLFSNSSYLAGFACLLCAVLSIHRVIRAISVAKWLQLAVEAVGFMASSTAYDVLYVYCVELFPTNVRNTAVSLLRQAFMLGASAAPLLVALGRESAMMSFIVFGVASVLSGIVSLWLRETRNAPLYETLAQQGKAEEIENETIMIT",
    "output": "High affinity carnitine transporter involved in the active cellular uptake of carnitine. Also transports organic cations. Regulates lateral root development."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKLKQIELKNFRNYEDLKLDFHPNLNIFLGQNAQGKTNILEAIHFLALTRSHRTSHDKELICWSGQEMKVSGLVEKAHATVPLEVQLSSKGRIAKANHLKENRLADYIGQLKILMFAPENLELVKGSPATRRRFMDIELGQIHAVYLYDSMRYNRALKERNAYLKFDQAKIDKNFLTVLDEQLAEHGNKIMFERKTFIEKLEIHAKKIHEQLTHGLETLKITYNQNVKTDFSKELLSRQDHDIFRHQTTVGPHRDDLQFFINEINVADFGSQGQQRTVALSIKLAEIDLIFEETGEYPILLLDDVMSELDNHRQLDLIETSLGKTQTFITTTTLDHLKNLPENLSIFHVTDGTIEKEKE",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSSSSLPTKSSNALLSVNFNQDHSCIAVGTRDGYSITNCEPFGRVYTNNAGPTSLVEMLFCTSLVALVATSDTDPKSNASPRRLQIVNTKRQSVICELLFPTAILGVKLNRRRLVVVLEQEIYIYDISNMKLLHTIETSPNPMAICALSPSSENCFLAYPSPVASPTSPFSNSGASSSAEANTTAGDVLIFDLLSLSVTNVIQAHKTPISALALNATGTLLATASDKGTVIRVFSIPAAQKLHQFRRGSYAARIYSLNFNAVSTLLAVSSDTETVHIFKLSSGAGAGAKGRSSSNGGESPSLNSFDGSSDSSSPPGSTTNATRGGYEAFMGKHKAAKSNGISGTLRRRSMALGRGITGSVGGYLPNSLTEMWEPSRDFAFLKLPSQGVSSVVALSSTTPHVMVVTSEGYFYSYAIDLEHGGECILMKQYSLIDPDLDTTSTARSDTATPSLAD",
    "output": "The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "NLMQFELLIMKVAGRSGIVWYSD",
    "output": "Snake venom phospholipase A2 (PLA2) that shows a moderate inhibition of ADP-induced human platelet aggregation when tested on platelet rich plasma. Exhibits moderate hydrolytic activities and prefers the anionic micelles (dPPC with deoxycholate) to the zwitterionic micelles (dPPC with Triton X-100). PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEPELDLTLKLGLPNSTVETHLTLSPPTTTTDQGTNVVDGGEVINHRRGLLGDDEVIHNEPTRNNVEFNIRIYNYVFQQFVGAPNTLNFAPYPMPPSPAPAPETPPVSDEYVLIDVPARRARRNNSTVMTNSWKENATPKRIRGCGGFCGGRIEGMKKCTNMNCNALNTPMWRRGPLGPKSLCNACGIKFRKEEERKAKRNVVIVLDD",
    "output": "Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQIQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS",
    "output": "Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFNMSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGTHLLATLDEMFNPGQEVLDAWGKAYGVLANVFIHREAEIYHENASKDGGWEGTRPFRIVAKTPRSALITSFEFEPVDGGTVAEYRPGQYLGVWLKPEGFAHQEIRQYSLTRKPDGKGYRIAVKREDGGQVSNWLHHHASVGDGVHLAAPAGDFFMNVAADTPVSLISAGVGQTPMLAMLDTLAKEQHTAQVNWFHAAENGDVHAFADEVSELGRTLPRFTAHTWYREPTESDRAQRLFDSEGLMDLSKLEAAISDPAMQFYLCGPVGFMQFAAKQLVSLGVNNENIHYECFGPHKVL",
    "output": "Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKKKLFVSELIKHFDLEVLNHDFPEIEDREILTPSIKRLGLELSGHFIYDAISGVIVGWGTNESKFFEKIGSEKAKSSIEEIFSRKIPMLVLSKGFDKNYYSTIIEIANKHKTPVIFYKASLSEINTILGIYLLQYFAKKVQVHGTLVSVFGMGILIVGDSGLGKSEAALELVQKGHVLISDDAVLVSHYGNKYFGKAPYITKNLIEVRGLGLIDILSVHGLKSVLPECEINFVVELKDYEQNKSNFDRLGNKVLKYQIGEWKIPKIEIPIRQGRSVASLIEASANMFLSKLNGHDVLAMIQERSLNDE",
    "output": "Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr) (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "SLLRKNVDSLTEEEILTLQSVMRELQNDSSEHGFQSIASFHGSPPLCPSPEANKKVACCVHGMASFPQWHRIFTKQMEAALMGHGAKVGMPYWDWTTSFTKLPRFIPYDDEQLNPFVRITDLEDHFTTRDPQPELFKDPEGGDESFFFRQVLIALEQRDYCDFEVQFEVIHNSIHYWIGGHQKYGMSTLEYTAYDPLFFIHHSNVDRLWAIWQELQKYRGLPYDESDCGVELMREPLQPFAQTSATNPNNVTRAHSTPKSLFNYRQLAGYTYDTLTLNGMTISQLESSLLRLQKEEDRVFAGFLLRGIGSSADVTFDLCDKDEHCDFAGTFAVLGGPLEMPWSFDRLFKMDVTKVFKQMRLRPDDSEYHFELEVTARAGTDLSPELLKPGSVSFLPGRKIQNTPDVR",
    "output": "Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAASPKINRREHILQCLATMLETSPGQRITTAKLAAEVGVSEAALYRHFPSKARMFEGLIDFIEESLLSRINLIMDEEKDTMRRCQLLLQLLLVFAERNPGISRVLNGDALLGENERLRNRTGQIFSKVETHLKQILREKTLREGKGFNLDEAILANLLLAVAEGRIAQFVRSDFKNKPTEHFAEQWQFIQQQLLQS",
    "output": "Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLKFNEYFTGKVKSIGFDSDSIGQASVGVMEKGEYTFSTAKPEEMTVITGSLKVLIPGSSGWEVFNPGETFYVPANSEFNLQVAEASSYLCKYLS",
    "output": "Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIDRDGFRANVGLILCNQDDRVLWARRAREKAWQFPQGGVKESETTEEAAYRELEEEVGLGVEHVKIIGCTRSWLRYRLPNRYVRYGNKPLCIGQKQIWYLFRFVGEEQDVQLNLTDKPEFDYWCWVNYWYPLREIVYFKRKVYQRALNELAPLIFPDHQSLPPARSNYRKRRRQKTRSRI",
    "output": "Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLTCLSRRVLVGLFSIGILPLNAMASGSWVADDIGITQSVRGVAISAKPLQSPVALAQDNARIVSISWRYQLMSAAPDGLQVKLCTPTRCMPLEGGSGLSRGLAGEAAATQLTFIYFIAGKGRVNPPLQVINHQVIVNYR",
    "output": "Not essential for flagellar formation and function."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLRSHCMEFSEELKTLKDQVRFDGSFRTGTFSNIVIAGMGGSGIAGRIFSEMYSAKPVFVCDDYHIPEFVDGNTEFIAVSYSGNTEETLSAAEEAIKKGAKVHAITSGGRLSEMGVDTIKIPGGLQPRSAVGYLTMPIINTFIRPKHEDIEEAAGLLSDLDKNNTVQENIATEIYAGRRIPVIYGSTPYRSVAYRWKTQFNENAKILAYSNYFSELNHNDTMPLRDTYRKDEFYFMAFDSTDERIRKRIEVTQKITGTSFKKIEARGSSLIARIFYLIHFGDYVTYHLARIRNVDPQDVSAIEDLKKRIS",
    "output": "Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPEFQLQRRLAADIAGVGLNNIKFNPERLEEVEEALTREDIKKLIKERAVIVNPKRGISSGRLKERKHKRRSKGEGRKHGSRKGKSGARTGDKEIWINKIRKIRRYIRWLRDNNVIDKHTYRLLYKRAKGNYFKNLSDVKSYLRQMGHKV",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MHFETVIGLEVHVELKTDSKMFSPSPAHFGAEPNSNTNVIDLAYPGVLPVVNRRAVDWAMRASMALNMEIATESKFDRKNYFYPDNPKAYQISQFDQPIGEHGYIDIEVDGETKRIGITRLHMEEDAGKSTHKDGYSLVDLNRQGTPLIEIVSEPDIRSPQEAYAYLEKLRSIIQYTGVSDCKMEEGSLRCDANISLRPYGQEEFGTKAELKNLNSFNYVRKGLEYEEKRQEEELLNGGEVLQETRRFDESTGKTILMRVKEGSDDYRYFPEPDIVPLYVDEAWKERVRQTIPELPDARKEKYVNEYGLPAYDAHVLTLTKEMSDFFEGAVEAGADVKLTSNWLMGGVNEYLNKNQVELQDTKLTPENLAGMIKLIEDGTMSSKIAKKVFPELAENGGDAKQIMEDKGLVQISDESVLLNFVNEALDNNPQSVEDFKNGKGRAKGFLVGQIMKASKGQANPQMVNKLLQQELDKR",
    "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDSLRLRPSLLAARAPGAASLPPLRRDHFLPPLCSIHRNGKRPVSLSSQRTQGPSFDQCQKFFGWKSSHHRIPHRPTSSSADASGQPLQSSAEAHDSSSIWKPISSSLDAFYRFSRPHTVIGTALSIVSVSLLAVENLSDVSPLFLTGLLEAVVAALFMNIYIVGLNQLFDIEIDKVNKPTLPLASGEYSPATGVALVSAFAAMSFGLGWAVGSQPLFLALFISFILGTAYSINLPFLRWKRSAVVAALCILAVRAVIVQLAFFLHIQTFVFRRPAVFTRPLIFATAFMTFFSVVIALFKDIPDIEGDRIFGIKSFSVRLGQKKVFWICVGLLEMAYCVAILMGATSACLWSKYATVVGHAILAAILWNRSRSIDLTSKTAITSFYMFIWKLFYAEYLLIPLVR",
    "output": "Involved in the synthesis of tocopherol (vitamin E). Catalyzes the condensation of homogentisate and phytyl diphosphate to form dimethylphytylhydroquinone (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTTISSFPSIFVPLVGLVFPAIAMASLSLYVQKTKIF",
    "output": "May help in the organization of the PsaL subunit."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASLKDLKNRIGSVKSTQKITKAMQMVAAAKLRRAQEAAEAARPYAQRMAAVMANLSTAMSGTPGASPLLVGTGKSDAYLLVVMTADRGLCGGFNTNIVKKARERINALKAEGKDVKVICVGKKGADQLKRNFASLIVDKMELSGEKTITGATSVRIGDKIRHMFENGEFDVCELVSAEFVSVISQKPRAKVLIPAIDAIDEGVERPDLGGAVYDAEPDEETILNVLLPRYADTVILSALLENVAGEMGAKMAAMDNATRNAGELIDKLNLVYNRTRQAQITTELTEIISGAEAL",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTQMLTRPDVDLVNGMFYADGGAREAYRWMRANEPVFRDRNGLAAATTYQAVLDAERNPELFSSTGGIRPDQPGMPYMIDMDDPQHLLRRKLVNAGFTRKRVMDKVDSIGRLCDTLIDAVCERGECDFVRDIAAPLPMAVIGDMLGVLPTERDMLLKWSDDLVCGLSSHVDEAAIQKLMDTFAAYTEFTKDVITKRRAEPTDDLFSVLVNSEVEGQRMSDDEIVFETLLILIGGDETTRHTLSGGTEQLLRHRDQWDALVADVDLLPGAIEEMLRWTSPVKNMCRTLTADTVFHGTELRAGEKIMLMFESANFDESVFGDPDNFRIDRNPNSHVAFGFGTHFCLGNQLARLELRLMTERVLRRLPDLRLADDAPVPLRPANFVSGPESMPVVFTPSAPVLA",
    "output": "Involved in the utilization of cholesterol as the sole carbon and energy source by degrading the side chain. Primarily catalyzes the sequential oxidation of the terminal methyl of cholest-4-en-3-one into (25R)-26-hydroxycholest-4-en-3-one (alcohol), (25R)-26-oxocholest-4-en-3-one (aldehyde), to finally yield the carboxylic acid (25R)-3-oxocholest-4-en-26-oate. Also able to sequentially oxidize cholesterol itself, not only cholest-4-en-3-one."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQLIDADVTVIGSGPGGYVAAIKAAQLGFKTVCVEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVIHVNGYGKITGKNQVTATKVDGGTQVVDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGIGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF",
    "output": "Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A. In monomeric form may have additional moonlighting function as serine protease (By similarity). Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEFSLDNNINNGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITANTDVQALKHSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQVISESLQGADMIFITAGMGGGTGTGAAPVVAKIAKELGALTVGVVTRPFSFEGPKRGRFAAEGIALLKENVDTLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTVMENQGTALMGIGVASGEERVIEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEAQDASDIVTNAASGDVNIILGTSINEDLGDEIRVTVIATGIDESKKDRKPHRQTRQAVQPMQQTTQSVEMDQPKSQEEASAFGDWDIRREQNTRPKVDESSLEQVDKKEFDTFHREEPNHNDDELSTPPFFRRKR",
    "output": "Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAYSYTEKKRIRKSFAELPTVMDIPYLLSIQVDSYEQFLQEHKKPKARENTGLQAAYSSIFPIESHSGNAELQFVEYYLGTPEFDERECILRGSTFAAPMRVKIRLIIKDKDSKDKDSKAAIKDIREQSVYMGEMPLMTANGTFIINGTERVIVSQLHRSPGVFFDHDKGKSHSSGKVLYNARIIPYRGSWLDFEFDAKDLVFARIDRRRKLLASIILRALGLSTSEILDLFFDKVKVYKGEEQFEIDLVADRLRGEMAQFDIVTPEGDVVVEQGKRINARRIRQLEEAGMTKISIPDEYLYERILAEDIIVNDEVIARANTLIDHELLVKLSAFEASESIKEFSILFTNDIDQGSYIADTLRADSTSSREEALIEIYKVMRPGEPPTVETAEKLFDSMFFNADRYDLSNVGRMKFNRRLGLDFVDTDDADIQRERSVLTNADIVNVLKELIEIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSSAESDNLSPQDLINSKPVAAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHDTHYGRVCPIETPEGPNIGLINSLATFAKTNSFGFLETPYRRVVDGKVTDVIEYLSAIEEVGTVIAQADSPVTADGALSDEMVSVRSYGEFVRMPPEKVTHMDVSPSQVVSVAAGLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERHVARDSGVCVIAKRGGVIEDVDASRIVVRVNEAEMIAGEAGIDIYNLVKYTRSNQNTCINQRIIVNQGDEIAFGDILADGPSTDLGELALGQNIRIAFMPWNGYNFEDSILLSEKVVKEDRFTTIHIQELTCVARDTKLGTEEITADIPNVGEAALSSLDEAGIVYIGAEVDAGDILVGKVTPKGETQLTPEEKLLRAIFGEKAADVKDTSLRVPTSSKGTVIDVQVFTRDGVEKDARARAIEKSQLDSYRKDLKEELRIFEEAARGRIGNLLDGQKVSGGSGLKAGTIMALADMKDMSLETLLDIQPVEEEISERLTQIAEYLVDKQKDIDVKFAEKKRKLTAGDDLQHGVQKIVKVYLAVKRRIQPGDKMAGRHGNKGVVSRIMPVEDMPYDEHGNTVDIVLNPLGVPSRMNIGQVLETHLGMAAKGLGEKIDGMLKSQAAIKDLREFLDKIYNQVGGEQVDLDSLTDDDIMALADNLRAGVPMGTAVFDGAKESQVKDLLELAGMDRDGQQTLYDGRTGQKFDRKVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGATYTLQEMLTVKSDDVEGRTRMYKNIVDGEQYMDPGMPESFNVLTKEIKSLGINIELKQTH",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKVGVVGLQGDVSEHIEATKMAIEKLELPGEVIWLKRPEQLKGVDAVIIPGGESTTISRLMQRTGLFEPIKKMVEDGLPVMGTCAGLIMLAKEVLGATPEQKFLEVLDVKVNRNAYGRQVDSFEAPVKLAFDDEPFIGVFIRAPRIVELLSEKVKPLAWLEDRVVGVEQENIIGLEFHPELTNDTRIHEYFLRKVI",
    "output": "Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIFDVKAPILGFETIHKMHLQKIDEIFLRLNSAEDNSVVSFTLVNPFALRKYEFEVPTPLKILLELEGAKSVLVANIMVVQTPIELSTVNYLAPLIFNLDKQLMGQVVLDSKKYPHYHLRENILSHTHE",
    "output": "Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRLNTLSPANGARHSRKRLGRGIGSGFGKTSGRGHKGQKSRSGSSIRRGFEGGQMPLYRRLPKFGFNSRKKNITTEVRLSDLSNLSTNIIDLNVLKQENIIKKNIKYAKIILSGKLTVPLIIRGLLVSKGARSEIENTGGKVEG",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSERNQRKVYTGRVVSDKMDKTITVLVETYKTHSLYGKRVKYSKKYKAHDEQNQAKLGDIVKIMETRPLSATKRFRLVEIVEEAVVI",
    "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKIAIYPGSFDPVTNGHIDIIQRGRHLFDKIIVSILLNPGKKALFSLDERLDMLTESLKDIDGVEVDSFAGLLIDYAERKNAKAILRGMRAVSDFEYEFQMALMNRRLNRDIQTVFLMTGMRWIYTSSSIIKEAATFGGDISGMVPAIVEKKLEEKIGYVVNHKKAED",
    "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKIGTQNQAFFPENILEKFRYIKEMGFDGFEIDGKLLVNNIEEVKAAIKETGLPVTTACGGYDGWIGDFIEERRLNGLKQIERILEALAEVGGKGIVVPAAWGMFTFRLPPMTSPRSLDGDRKMVSDSLRVLEQVAARTGTVVYLEPLNRYQDHMINTLADARRYIVENDLKHVQIIGDFYHMNIEEDNLAQALHDNRDLLGHVHIADNHRYQPGSGTLDFHALFEQLRADNYQGYVVYEGRIRAEDPAQAYRDSLAWLRTC",
    "output": "Catalyzes the epimerization at C4 of 3-dehydro-D-gulosides leading to 3-dehydro-D-glucosides. Probably functions in a metabolic pathway that transforms D-gulosides to D-glucosides. Can use methyl alpha-3-dehydro-D-glucoside and methyl beta-3-dehydro-D-glucoside as substrates in vitro. However, the actual specific physiological substrates for this metabolic pathway are unknown. Cannot act on D-psicose, D-fructose, D-tagatose, D-sorbose, L-xylulose, or L-ribulose."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQLKRVAEAKLPTPLGDFLMVGFEELATGHDHAALVFGDISGKTPVLARVHSECLTGDALFSLRCDCGFQLEAALTHIAEEGRGILIYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVDEVRLLTNNPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAAKMGHLLSK",
    "output": "Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADEVILLDFWPSPFGVRARIALREKGVEFEYREENLRDKSPLLLQMNPVHKKIPVLIHNGKPVCESMNVVQYIDEVWSDKNPILPSDPYQRAQARFWVDFVDTKLFEPADKIWQTKGEEQETAKKEYIEALKILETELGDKPYFGGDTFGFVDIAMTGYYSWFEASEKLANFSIEPECPTLMASAKRCLQRESVVQSLHDSEKILAFAYKIRKIYCV",
    "output": "May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGEKDSETAPIWGKTRERERSNNNNIQPMDLESSSSVSGQQRSLTQSRSSYEERGRGVKEFRSWFPWLIPCFVVANVAVFVITMYVNNCPKKSGDCFADFLGRFSFQNTRENPLLGPSSLTLQTMGGLDVKKVVKGDEGWRLLSCNWLHGGVVHLLMNMLTLLFIGIRMEREFGFIRIGLLYLISGFGGSILSALFLRSNISVGASGAVFGLLGGMLSEIFINWTIYSNKVVTIVTLVLIVAVNLGLGVLPGVDNFAHIGGFATGFLLGFVLLIRPHYGWINQRNGPGAKPHRFKIYQGILWTISLLILVAGFIVGLISLFNNVDGNEHCSWCHYLSCVPTSKWSCNREPASCTTTQLGNQLSMTCLRNGKSASYILANPSDSRINSLCVQLCR",
    "output": "Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSTDSIEVAIIGAGITGITLALGLLSRGIPVRVYERARDFHEIGAGIGFTPNAEWAMKVVDPRIQAAFKRVATPNASDWFQWVDGFNESGTDPRETEEQLLFKIYLGERGFEGCHRADFLGELARLLPEGVVTFQKALDTVEPAADNSLGQLLRFQDGTTATAHAVIGCDGIRSRVRQILLGEDHPTASAHYSHKYAARGLIPMDRAREALGEDKVATRFMHLGPDAHALTFPVSHGSLLNVVAFVTDPNPWPYADRWTAQGPKKDVTAAFSRFGPTMRTIIDLLPDPIDQWAVFDTYDHPPNTYSRGAVCIAGDAAHAAAPHHGAGAGCGVEDAAVLCAVLHMAAKKVNTAKTGSEGKAALITAAFETYDSVCRERAQWLVESSRVIGNLCHDEVYWRSHRIWDYDIDAMMRETAEVFEAQVAGVARN",
    "output": "FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of azaphilones, a class of fungal metabolites characterized by a highly oxygenated pyrano-quinone bicyclic core and exhibiting a broad range of bioactivities . In the first step, the non-reducing polyketide synthase azaA forms the hexaketide precursor from successive condensations of five malonyl-CoA units, presumably with a simple acetyl-CoA starter unit . The reactive polyketide chain then undergoes a PT-mediated C2-C7 cyclization to afford the aromatic ring and is eventually released as an aldehyde through the R-domain . The putative ketoreductase azaE is proposed to catalyze the reduction of the terminal ketone resulting in the early culture product FK17-P2a . The monooxygenase azaH was demonstrated to be the only enzyme required to convert FK17-P2a to azanigerone E . AzaH first hydroxylates the benzaldehyde intermediate FK17-P2a at C4, which triggers the formation of the pyran-ring to afford azanigerone E . In parallel, the 2,4-dimethylhexanoyl chain is synthesized by the HR-PKS azaB and is proposed to be transferred to the C4-hydroxyl of azanigerone E by the acyltransferase azaD directly from the ACP domain of azaB . Alternatively, the 2,4-dimethyl-hexanoyl chain may be offloaded from the HR-PKS as a carboxylic acid and converted to an acyl-CoA by azaF . The resulting acyl-CoA molecule could then be taken up as a substrate by AzaD to form azanigerone B . To yield the carboxylic acid substituent in azanigerone A, the hydroxypropyl side chain of azanigerone B would need to undergo a C-C oxidative cleavage catalyzed by cytochrome P450 AzaI . AzaI is proposed to act on a vicinal diol that leads to a C-C bond scission either through an alkoxyradical intermediate or a peroxy complex . In the biosynthesis of azanigerone A, azanigerone B first undergoes hydroxylation at C10, possibly catalyzed by one of the two FAD-dependent monooxygenases encoded in the cluster, azaG or azaL, resulting in the vicinal diol azanigerone C . Oxidative cleavage of azanigerone C by azaI would yield the corresponding aldehyde derivative of azanigerone A . Finally, the dehydrogenase azaJ is proposed to convert the aldehyde functional group into the carboxylic acid, completing the conversion from azanigerone B to azanigerone A . Alternatively, the oxidation of aldehyde to carboxylic acid may be catalyzed by the same P450 enzyme azaI via consecutive oxidation or by endogenous alcohol dehydrogenase ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDAIKCSSSFLHHTKLNTLFSNHTFPKISAPNFKPLFRPISISAKDRRSNEAENIAVVEKPLKSDRFFISDGLPSPFGPTVRDDGVNFSVYSTNSVSATICLISLSDLRQNKVTEEIQLDPSRNRTGHVWHVFLRGDFKDMLYGYRFDGKFSPEEGHYYDSSNILLDPYAKAIISRDEFGVLGPDDNCWPQMACMVPTREEEFDWEGDMHLKLPQKDLVIYEMHVRGFTRHESSKIEFPGTYQGVAEKLDHLKELGINCIELMPCHEFNELEYYSYNTILGDHRVNFWGYSTIGFFSPMIRYASASSNNFAGRAINEFKILVKEAHKRGIEVIMDVVLNHTAEGNEKGPIFSFRGVDNSVYYMLAPKGEFYNYSGCGNTFNCNHPVVRQFILDCLRYWVTEMHVDGFRFDLGSIMSRSSSLWDAANVYGADVEGDLLTTGTPISCPPVIDMISNDPILRGVKLIAEAWDAGGLYQVGMFPHWGIWSEWNGKFRDVVRQFIKGTDGFSGAFAECLCGSPNLYQGGRKPWHSINFICAHDGFTLADLVTYNNKNNLANGEENNDGENHNYSWNCGEEGDFASISVKRLRKRQMRNFFVSLMVSQGVPMIYMGDEYGHTKGGNNNTYCHDNYMNYFRWDKKEEAHSDFFRFCRILIKFRDECESLGLNDFPTAKRLQWHGLAPEIPNWSETSRFVAFSLVDSVKKEIYVAFNTSHLATLVSLPNRPGYRWEPFVDTSKPSPYDCITPDLPERETAMKQYRHFLDANVYPMLSYSSIILLLSPIKDP",
    "output": "Involved in the trimming of pre-amylopectin chains. Accelerates the crystallization of nascent amylopectin molecules during starch synthesis. ISA1 and ISA2 work exclusively together as a multimeric holoenzyme. ISA1-ISA2 removes preferentially branches that are very close to other branches. Promotes negative gravitropic responses in shoots by facilitating starch granules (statoliths) formation in hypocotyls ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQIKRSIEKIPGGMMLVPLFLGALCHTFSPEAGKYFGSFTNGMITGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVEVGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGTAGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTVIAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK",
    "output": "Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAAARCLRWGLSRAEAWLLPPPTSCCHRALHRQVEGTEFRSAYSLDKLYPESRGADTAWRVPGDAKQGNDDIPVDRLTISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKMALTHKNKINRAGELILTSEYSRYQFRNLADCLQKIRDMIAEASQPATEPSKEDAALQKLRIENMNRERLRKKRINSAIKTSRRVGTD",
    "output": "Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTVLAPAWSPNSSLLLLLLLLSPCLRGTPDCYFSHSPISSNFKVKFRELTDHLLKDYPVTVAVNLQDEKHCKALWSLFLAQRWIEQLKTVAGSKMQTLLEDVNTEIHFVTSCTFQPLPECLRFVQTNISHLLKDTCTQLLALKPCIGKACQNFSRCLEVQCQPDSSTLLPPRSPIALEATELPEPRPRQLLLLLLLLLPLTLVLLAAAWGLRWQRARRRGELHPGVPLPSHP",
    "output": "Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAAQRLAALHAAAPSAFSSTSSASHGRPAARSSTTALLPVALPRASATLRAAPSRLLPQEAKAAGSGRSVMCMASASASAASAAVASGAAELKAAREDIRELLKTTHCHPILVRLGWHDSGTYDKNIKEWPQRGGANGSLRFDVELKHGANAGLVNALKLVQPIKDKYPNISYADLFQLASATAIEEAGGPKIPMTYGRIDVTGPEQCPPEGKLPDAGPSAPADHLRKVFYRMGLDDKEIVVLSGAHTLGRSRPERSGWGKPETKYTKNGPGAPGGQSWTAEWLKFDNSYFKEIKEKRDQDLLVLPTDAALFEDPTFKVYAEKYAEDQEAFFKDYAGAHAKLSNLGAKFNPPEGFTLDG",
    "output": "Plays a key role in hydrogen peroxide removal."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRRTLVYGLGESGEAATRALLQRGERPLAADAASGEGPRRVLEELGVEGVLGAGPEVLDGVDRVVVSPGVRPRDAVLREARRRGIPVISEVGLGLELLGPGVRVAAVTGTNGKTTVVDMARHILRVAGVAHAVAGNSWRALTGCLEEVRRAGVLVLEVSSFQLHHLPPPGFEVAALLNVRPDHLNWHSSFEEYARDKLRVFGGQGPGDLALLSADDPICRRAAGGLRAEVVLVGEGETGVRDGRLLLRGEFLAGERELGFAGGHNLKNALFAAAAAARLGAGLEAIREALRGYRLKPHRMQVVAEEGGVTYIDDSKATNPAAVAAALLSLGGRPAVLILGGSEKETDFEEVLPHLGGCRAVVCQGEAGPRLRDFLSERWGGEVVLAGDLASAVEAARRLARPGDAVLLSPGCASFDQFSGYEERGEAFARLAGGRRAVRG",
    "output": "Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVPFVLASASPARRQLLQQIGIDPIIQPSHFDESVIQAATPTELVRLLARCKAETVAQSYSAPALILGCDSVLVLGGEIYGKPASPEMAIARWQQMRGQTADLLTGHALIDLAQGRTCVEVESTQVVFAQVSDAEIAAYVASGEPLACAGCFALDGQGGAFVEKIVGTPSNVIGLSLPLLRRLLLSLGYTLADVQNKK",
    "output": "Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEANHQRNDLGLVALTMLAQYHNISLNPEEIKHKFDLDGKGLSLTSWLLAAKSLALKAKHIKKEISRLHLVNLPALVWQDNGKHFLLVKVDTDNNRYLTYNLEQDAPQILSQDEFEACYQGQLILVTSRASVVGQLAKFDFTWFIPAVIKYRKIFLETLIVSIFLQIFALITPLFFQVVMDKVLVHRGFSTLNIITVALAIVIIFEIVLSGLRTYVFSHSTSRIDVELGAKLFRHLLSLPISYFENRRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILGSLPCYILWSIFISPILRRRLDDKFARSADNQAFLVESVTAINMIKAMAVAPQMTDTWDKQLASYVSSSFRVTVLATIGQQGVQLIQKTVMVINLWLGAHLVISGDLSIGQLIAFNMLSGQVIAPVIRLAQLWQDFQQVGISVTRLGDVLNSPTEQYQGKLSLPEIKGDISFKNIRFRYKPDAPTILNNVNLEIRQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLNRSIRENIALSDPGMPMERVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQNMQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYLHQLQLN",
    "output": "Part of the ABC transporter complex LktBD involved in leukotoxin export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKLRANRVGEQMKKELGDIISRKIKDPRIGFVTVTDVQVSGDLQIAKVYISVLGDEEQKENTLKGLAKAKGFIRSEIGQRIRLRKTPEITFEFDESIGYGHRIDTLLHEINKDGKREE",
    "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MALPSLGQDSWSLLRVFFFQLFLLPSLPPASGTGGQGPMPRVKYHAGDGHRALSFFQQKGLRDFDTLLLSDDGNTLYVGAREAVLALNIQNPGIPRLKNMIPWPASERKKTECAFKKKSNETQCFNFIRVLVSYNATHLYACGTFAFSPACTFIELQDSLLLPILIDKVMDGKGQSPFDPVHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDIFLRWLHADASFVAAIPSTQVVYFFFEETASEFDFFEELYISRVAQVCKNDVGGEKLLQKKWTTFLKAQLLCAQPGQLPFNIIRHAVLLPADSPSVSRIYAVFTSQWQVGGTRSSAVCAFSLTDIERVFKGKYKELNKETSRWTTYRGSEVSPRPGSCSMGPSSDKALTFMKDHFLMDEHVVGTPLLVKSGVEYTRLAVESARGLDGSSHVVMYLGTSTGSLHKAVVPQDSSAYLVEEIQLSPDSEPVRNLQLAPAQGAVFAGFSGGIWRVPRANCSVYESCVDCVLARDPHCAWDPESRLCSLLSGSTKPWKQDMERGNPEWVCTRGPMARSPRRQSPPQLIKEVLTVPNSILELPCPHLSALASYHWSHGRAKISEASATVYNGSLLLLPQDGVGGLYQCVATENGYSYPVVSYWVDSQDQPLALDPELAGVPRERVQVPLTRVGGGASMAAQRSYWPHFLIVTVLLAIVLLGVLTLLLASPLGALRARGKVQGCGMLPPREKAPLSRDQHLQPSKDHRTSASDVDADNNHLGAEVA",
    "output": "Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling . Regulates glutamatergic and GABAergic synapse development . Promotes the development of inhibitory synapses in a PLXNB1-dependent manner and promotes the development of excitatory synapses in a PLXNB2-dependent manner . Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity . Promotes phosphorylation of TIMD2 . Inhibits angiogenesis . Promotes axon growth cone collapse . Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPEQAQQGEQSVKRRRVTRACDECRKKKVKCDGQQPCIHCTVYSYECTYKKPTKRTQNSGNSGVLTLGNVTTGPSSSTVVAAAASNPNKLLSNIKTERAILPGASTIPASNNPSKPRKYKTKSTRLQSKIDRYKQIFDEVFPQLPDIDNLDIPVFLQIFHNFKRDSQSFLDDTVKEYTLIVNDSSSPIQPVLSSNSKNSTPDEFLPNMKSDSNSASSNREQDSVDTYSNIPVGREIKIILPPKAIALQFVKSTWEHCCVLLRFYHRPSFIRQLDELYETDPNNYTSKQMQFLPLCYAAIAVGALFSKSIVSNDSSREKFLQDEGYKYFIAARKLIDITNARDLNSIQAILMLIIFLQCSARLSTCYTYIGVAMRSALRAGFHRKLSPNSGFSPIEIEMRKRLFYTIYKLDVYINAMLGLPRSISPDDFDQTLPLDLSDENITEVAYLPENQHSVLSSTGISNEHTKLFLILNEIISELYPIKKTSNIISHETVTSLELKLRNWLDSLPKELIPNAENIDPEYERANRLLHLSFLHVQIILYRPFIHYLSRNMNAENVDPLCYRRARNSIAVARTVIKLAKEMVSNNLLTGSYWYACYTIFYSVAGLLFYIHEAQLPDKDSAREYYDILKDAETGRSVLIQLKDSSMAASRTYNLLNQIFEKLNSKTIQLTALHSSPSNESAFLVTNNSSALKPHLGDSLQPPVFFSSQDTKNSFSLAKSEESTNDYAMANYLNNTPISENPLNEAQQQDQVSQGTTNMSNERDPNNFLSIDIRLDNNGQSNILDATDDVFIRNDGDIPTNSAFDFSSSKSNASNNSNPDTINNNYNNVSGKNNNNNNITNNSNNNHNNNNNDNNNNNNNNNNNNNNNNNSGNSSNNNNNNNNNKNNNDFGIKIDNNSPSYEGFPQLQIPLSQDNLNIEDKEEMSPNIEIKNEQNMTDSNDILGVFDQLDAQLFGKYLPLNYPSE",
    "output": "Probable transcription factor involved in the stress response."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTNIRKSHPLIKIINESFIDLPAPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGMYYGSHTFSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGLTSDSDKIPFHPYYTIKDILGLLLLILILMLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVTALVLSILILAILPLLNTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFITIGQLASILYFLTILILMPISGMIENQLLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEQAPNMAEPRGPVDHGVQIRFITEPVSGAEMGTLRRGGRRPAKDARASTYGVAVRVQGIAGQPFVVLNSGEKGGDSFGVQIKGANDQEASGALGSDFELPENPYSQVKGFPAPSQSSTSDEEPGAYWNGKLLRSQSQASLAGPGPMDPSNRSTSMLELAPKVASPGSTIDTAPLSSVDSLINKFDSQLGGQSRGRTGRRTRMLPPEQRKRSKSLDSRLPRDTLEERERQSTNHWTPSTKYDNHVGSSKQPSQSQSPSPPSGFSRSRQTQDWVLQSFEEPRGRAQDPTMLQFKSTPDLLRDQQEAAPPGSVDHMKATIYGILREGSSESETSVRRKVSLVLEKMQPLVMISSGSTKAVAGQGELTRKVEELQRKLDEEVKRRQKLEPSRVGLERQLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEGLRHGLEAQVMELQNKLKQVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLQTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEAAVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKHLLDRTVDRLNKELEKIGEDSKQALQQLQAQLDDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLEAELDEEKNTVELLTDRVNRGRDQVDQLRTELLQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEEEIERLDGLRKKAQRELEEQHEVNEQLQARIKSLEKDSWRKASRSAAESALKHEGLSSDEEFDSVYDPSSIASLLTESNLQTSSC",
    "output": "Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "GIPCAESCVYIPCTVTALLGCSCSDKVCYN",
    "output": "Probably participates in a plant defense mechanism (By similarity). Has cytotoxic activity against HUVEC cells (LC(50)= 2.26 uM) and various cancer cells including HeLa (LC(50)= 3.48 uM), MCF-7 and K562 . Displays very weak hemolytic activity . Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE) ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MASNNVAQFAAELKMPAGVLLEQLQAAGVTKASEDDSLSETDKARLLDHLRKSHGSTDADKRKITLTKRHTSEIKQSDATGKARTIQVEVRKKRTFVRRDETSAENGDASNHVAEAEVDDLELQRREEEARHEAELLEKQAQELKARQEQLEREEAERQAREAAAEVERRRAEEEAAKKRAAAAAEAAAREQQTQASKPAQAAQPAAAKAEPVAAKAAEPVVARQSEQDDERAAAERAAQREAAKKAEDAARQAAEKARAEQEEIAKRRAAAEAEARAIREMMNTPRKAQVKAPEPAPKPAEPAKAAEAKGTLHKPARPAGEAPARPAAKKPAAAAPAATTTPSAGDKKKPGGGKGGWQDDAAKRRGIKTRGDTSGGVDRGWRGGPKGRGKHQDQNTTFQAPTEPIVREVHVPETITVADLAHKMAVKASEVIKSMMKLGQMVTINQMLDQETAMIIVEELGHHAVAAKLDDPEAMLVEGEVSDAESLPRPPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETPRGVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAGGVPLVVAINKIDKPDANPERVKQELVAEGVVPEEYGGDSPFVSVSAKTGAGIDDLLENVLLQAEVLELKAPVEAPAKGLVIEAKLDKGKGPVATILVQSGTLNRGDVVLAGSAYGRVRAMLDETGKPTKSAGPSIPVEIQGLSEVPQAGEEVIVMPDERKAREVALFRQGKFRDVKLAKQQAAKLENMLEQMGEGEVQYMPLIVKADVQGSQEALVQSLLKLSTDEVRVQIVHGAVGGISESDVNLATASKAVIIGFNTRADAQARKLAEANGVDIRYYNIIYDAVDDVKAAMSGMLAPEKREVVTGTVEVRQVFKVPKIGAVAGCMVTDGFVKRSSSVRVLRNNVVIFTGELDSLKRFKDDVKEVRQGFECGMSIKNFNDIVEGDQFEVFEVTEVARSL",
    "output": "One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQEHDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNVISHSRVKTDLKGTGDLFCAQLISGLLKGKALNDAVHRAGLRVLEVMRYTQQHESDELILPPLAEA",
    "output": "B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i.e. PNP, PLP and PMP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQFDNIDSALMALKNGETIIVVDDENRENEGDLVAVTEWMNDNTINFMAKEARGLICAPVSKDIAQRLDLVQMVDDNSDIFGTQFTVSIDHVDTTTGISAYERTLTAKKLIDPSSEAKDFNRPGHLFPLVAQDKGVLARNGHTEAAVDLAKLTGAKPAGVICEIMNDDGTMAKGQDLQKFKEKHQLKMITIDDLIEYRKKLEPEIEFKAKVKMPTDFGTFDMYGFKATYTDEEIVVLTKGAIRQHENVRLHSACLTGDIFHSQRCDCGAQLESSMKYINEHGGMIIYLPQEGRGIGLLNKLRAYELIEQGYDTVTANLALGFDEDLRDYHIAAQILKYFNIEHINLLSNNPSKFEGLKQYGIDIAERIEVIVPETVHNHDYMETKKIKMGHLI",
    "output": "Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSLSERQKEEINRAIAEYMQNNGYSESFSVFLKESSLSENDIKPLGGILEKKWTTVLRLQRKVNDLESKLQESQREINHGAPTRDKRQAADWIPRPPETQKLTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHAVECVEWAPDTAYTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQRCMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVWECR",
    "output": "Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as nuclear migration during cell division . Part of a complex with nud-2, which is recruited to the nuclear envelope by unc-83, where, in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells . Plays a role in GABAergic synaptic vesicle localization in the ventral nerve cord . Required for neuronal cell differentiation ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVDQEQFDISNVLIEALPYIKKFHNKKIMIKYGGHAMIDENAMSSTARDTVLLKYVGMQPIVVHGGGPEISRSMDKMGKEPKFIGGLRVTDKETMEIVKMVLVGKINTEIVSKLGFHGGKSVGISGKDSYLVEASRKGLTKVKHENGEVLEVDLGYVGKIDRVNKQLVDDLTNNNYIPVISPLGIDDDGNTLNLNADTVAGSIASEVNAEKLIVLTDVPGILTDPDDPESMIRRIRTDELKELIKDGIITGGMIPKVETCINAVENGVKTAHILDGRLNHSILLEIFTKHGIGTMVRE",
    "output": "Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLLVIGLGNPGKEYQYTRHNVGFIAIEKIANQYNSSFSTKKKFNCEIAETISDRQKIIFIKPTTYMNLSGKSVISVKTYYNIYPAKIFVIHDDIDLETGRIKFKTGGGNGGHNGLKSIDGVIGNNYNRIRIGVGRPQNNQDVADYVLNHFSKPEYKTVMQAIDRITSNFGLILENKLEEFKN",
    "output": "The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSRLFKITALVPSLSRTRTQRELQNTYFTKLVPYENWFREQQRIQKAGGKIIKVELATGKQGTNAGLQ",
    "output": "Rod linker protein, associated with allophycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVVATTIALYASPASTVCSTAHQINAHISCDLDLNSRSSSASSSTSSPTIGGLSLLFSGASVKSSSSSSSSHPSVGEELASIRHDRSEDRTLSGSFCYSPSKFIGSSYLKRDHQSPVSVLHGPISSGNSPPMRISRDRNLDGGSALRVGSSRLFNGFVRKAIGSCVDYDTDSVLVDEQLPFTMDDGFEGERRQPYARDLLRRAQLKHKIFEDESVIKAFYEAEKAHRGQMRATGDPYLQHCVETAMLLADIGANSTVVVAGILHDTLDDSFMSYDYILRTFGSGVADLVEGVSKLSQLSKLARENNTACKTVEADRLHTMFLAMADARAVLIKLADRLHNMMTLYALPPVKRQRFAKETLEIFAPLANRLGISSWKVKLENLCFKHLHPDQHHEMSDMLEDSFDEAMITSAIEKLEQALKKEGISYHVVSGRHKSLYSIYCKMLKKKLTMDEIHDIHGLRLIVDNEKDCYKALGVVHKLWSEVPGKLKDYISHPKFNGYQSLHTVVMGDGTIPLEVQIRTKEMHLQAEFGFAAHWRYKEGDCKHSSFVLQMVEWARWVVTWHFETMSKDGSSICSSEPLCSFPSHAEDCPFSYKPSGNQEGPVYVIVIENEKMTVQEFPENSTVSDLLRRAGPGSSRWSMYSIPAKEELRPRLNQTPVSDLKCKLKMGDVVELTPAIPDKSLTEYREEIQRMYDRGLAFSRPHRAATGTMVGWGS",
    "output": "Possesses ppGpp (guanosine 3'-diphosphate 5'-diphosphate) synthetase activity in vitro and is able to functionally complement E.coli relA mutants. May be involved in a rapid plant ppGpp-mediated response to pathogens and other stresses."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRAELAVYFIAGTQDIVRGTLPSVLEEALKAGITCFQYREKGAGALQTASERKEMALECQQLCAKYQVPFIINDDVALALEIGADGIHVGQNDEEIRQVIASCAGKMKIGLSVHSVSEAEEAERLGSVDYIGVGPIFPTISKADAEPVSGTAILEEIRRAGIKLPIVGIGGINETNSAEVLTAGADGVSVISAITRSEDCQSVIKQLKNPGSPS",
    "output": "Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAPKAEKKPASKAPAEKKPAAKKTATSGTKKRSKTRKETYSSYIYKVLKQTHPDTGISQKAMSIMNSFVNDIFERIAGEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSAAN",
    "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKLIFLLLLFGVSPIVCQDFEDGVFLAKITSIDEHDARKIGRRFGFEAQWKLQSYTDVYVGRRLRRRKRGIEDEIVAEMMLSQQVQFIEKLQGFRRYKRAPMTNKGYPVHVWNLTPSLYIREAWEDGFNASRVTVAVVDDGVDIKHVDLKSAFSPRVSFDFVRFGDLPTPKNSKEFEHGTQCAGLVAMEGQQCGLGVGHGATLGAIKLLGQDFLNDALEGDALAFQKDLIDIYSVSWGPKDDGKSAEKPAKFTEEAIKNGALHGRNGKGNIFVWASGNGGVNGDNCAYDGYVSNEYTLSFGVIDASGAPAAYGEGCSSVLAAVSGGDAMIQTTGLESTCSSISGSSASAAIASGIISLVLDANPTLSQRDIQHLIARTSNASAIRDVELYENSAGLNFHPKVGFGLLNAQKLVVMAATWENVAPQVTCEKMNLANGIIDNSDCDVTKVERVIVSGSIIHPHRGQVQIRLESPRGTISELLPLRPKDTSRDLLDWNFVSVNFFGENSRGIWKLHVTSEEDDVDFRVEMKMFKVVGTMS",
    "output": "Probable serine endoprotease which cleaves preproteins at paired basic amino acids . May process FMRFamide-like (flp) and neuropeptide-like protein (nlp) neuropeptides . In muscles, involved in neuronal retrograde signaling by regulating presynaptic activity and localization of synaptic vesicle fusion protein unc-13 at the neuromuscular junction (NMJ) . Acts in the intestine to regulate anterior body muscle contractions (aBOC) and the expulsion steps during the defecation motor program (DMP) . Probably by regulating DMP, required for fatty acid uptake by intestinal cells and therefore regulates the levels of triglycerides in the intestine . Plays a role in locomotion ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSSKLVLVLNCGSSSLKFAIIDATNGEEHISGLAECFHLPEARIKWKVDGGKQEAALGAGAAHSEALNFIVNTILAQKPALSAQLTAIGHRIVHGGEKFTSSVIVTDDVIQGIKDSIPFAPLHNPAHLIGIAEALKSFPNLADKNVAVFDTAFHQTMPEESYLYALPYSLYKDHGIRRYGAHGTSHFYVSQEAAKVLNKPLEELNVITCHLGNGGSVTAVRNGKCVDTSMGLTPLEGLVMGTRSGDLDPAIIFHLHDAMGMSVDQINTLLTKESGLLGLTEVTSDCRYVEDNYATKADAKRAMDVFCHRLAKYIGSYTALMDGRLDAVVFTGGIGENAAMVRELTLDKLGLLGFEIDHERNMAARFGKSGTITKDSSRLALVIPTNEELVIAQDAARLTA",
    "output": "Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQIPENIALADDSLVPFLAGETVRWSVKK",
    "output": "Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGYIPPPGDNDDNGKKSNKKTQNTSKPISSDSTPDGTTITIINPMSLIPRNPSFGLIWGPLTPASDNRPAMYTMVALQIAIGVRFFRYARTHLRRHPVPQAQFHAPPGLGVNSMISTTANQTYSAPPQQFLRRSKGDVFKSILAITTGSLLIFGSGLEIARMMLPYDPWYDEAQFYRKQAVRNGDKPNFWFGAYQYYQPMTYKEWHSKVSKWIDSVEKEIKVDETTFVIDKDGKARGGIGPAGVGYVNGAGQQSGAASAAAAVAKPLFQIRNRAKYQQIHAKLYNANETRMRELLANELNDTNVNELNKAERLDKILEGKSDLVNPNFNKPSISLGNHPMESDDEFEMVWLNFEPWDELKMETDYDIRLIPRYASVEELEQVDEGELFVVKKEELGETDNVVNESS",
    "output": "Component of the mitochondrial inner membrane i-AAA protease complex required for mitochondrial inner membrane protein turnover."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTAAAESERLRPPRVRAVRIWLTVVAALIAVMVLVGGATRLTESGLSIVEWKPVTGTLPPLTDAQWHAAFEGYKTIPQYRELNAGMTLYEFKTIFWWEWSHRLLGRVIGIAYLLPFLWFLWRGAIGPQWKRALWGIFALGALQGAVGWWMVASGLSQRTEVSQVRLAVHLTLALIIYAAIVWTLRRLADKPPIPAAARLKVTAIALLALTLLQLFLGALVAGLRAGRVFNTWPLIDGALIPSAERLWFEQPWWKNLFDNHLTVQFDHRMMAYALWALAAWHAIDAVRSRAGGAASGALWLFAALSLQAVLGILTVLHATPIGLALAHQAVGIVVLTLAVLQVERLTAPRLKALPRAMPVPVGQPG",
    "output": "Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKVILLFVLAVFTVFVSSRGIPLEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEQACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII",
    "output": "Cysteine proteinases 1 and 2 are believed to participate in the breakdown of protein during differentiation of Dictyostelium as a response to starvation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "SIMKMDGSQQEENLDVISTGSLGVDLALGVGGLPRGRVVEIFGPESSGKTTLCLEAIAQCQKNGGICAFIDAEHAFDPIYARKLGVKVEELYLSQPDTGEQALEICDTLVRSGGIDMVVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGHIKRTNTLVVFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGQIKKGDDVIGNETKVKVIKNKVAPPFRQAEFDILYGEGISWEGELIDLGVKHDIVEKSGAWYSYNGAK",
    "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTNMMKALVKAKPEEGLWMERVPLPEIGPNDVLIKVRKAAICGTDVHIWNWDEWARKTVPVPLVTGHEFVGEVVDVGSAVTEYRIGQRVSGEGHIVCGHCRNCRAGRGHLCRNTLGVGVHRPGAFAEYISLPQHNVVAIPDDVPDEIAAIFDPLGNAVHTALSFDLVGEDVLVTGAGPIGIMGALVAQCVGARKVVITDINPGRLALAKKLGVRHVVNAREEKLTDVMRKLGMTEGFDVGLEMSGSASAFRDMIDVMNNGGKIAILGIAPTGFEIDWNKVIFKMLHLKGIYGREMFETWYKMIALVQGPLDISGLITHRISADDYREGFAAMRSGEAGKVVMDW",
    "output": "Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "GLLDSIKGMAISAGKGALQNLLKVASCKLDKTC",
    "output": "Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C.albicans. Has no hemolytic activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPMERFLKDFTIPEKIEFLKSQDDGSYGKFTIYPFERGFGVTIGNTLRRVLLSSIEGYAITAMRVQSNNKDSSSKVVSSEFDLIPGVSEDTLEVIANIKNIHLKLREGEQRKTISFSVSGKDTNVLKASHFERDGVEVFNKDLVIATLSHDVNLDFEFQINYGRGYVSSEQNSKYLEEVNVIALDSIFSPIEKVSYSVEDTRVGQRSDYDKLVMEIWTTGVISAKDAIKKAASIVREFLFPLVDFEDSVSVSFDKSKSESSNLLDMSIEKLDLSVRSLNCLAKENVRTLGELISKNAEELSKARNFGKKSLEEIIEKLGSYQLFLGMSKEDALSVLSKNVKISE",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVAGMLMPLDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMTSLKARGLVRETFAWCHFYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRKEREEGAPETPVVSATIVGTLARPGPEPTPATDERDRVQKKTSTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFKISDIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPGAQDGVRANELQLRWQEYRELVLLLLQWIRHHTAAFEERKFPSSFEEIEILWCQFLKFKETELPAKEADKNRSKGIYQSLEGAVQAGQLKIPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVSKLQMEAGLCEEQLYQADSLLQSDIRLLASGKAAQRAGEVERDLDKADGMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVGAPVTQVTLQSTQRRPELEDSTLRYLHDLLAWVEENQRRIDGAEWGVDLPSVEAQLGSHRGMHQSIEEFRAKIERARNDESQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHGFVAAATKELMWLNEKEEEEVGFDWSDRNTNMAAKKESYSALMRELEMKEKKIKEIQNTGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENTAYFQFFSDVREAEEQLQKLQETLRRKYSCDRSITVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAIVQLKPRNPAHPVRGHVPLLAVCDYKQVEVTVHKGDQCQLVGPAQPFHWKVLSSSGSEAAVPSVCFLVPPPNQEAQEAVARLEAQHQALVTLWHQLHVDMKSLLAWQSLNRDIQLIRSWSLVTFRTLKPEEQRQALRNLELHYQAFLRDSQDAGGFGPEDRLVAEREYGSCSRHYQQLLQSLEQGEQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKDPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRSTQGAEEVLKTHEEHLKEAQAVPATLQELEVTKASLKKLRAQAEAQQPVFNTLRDELRGAQEVGERLQQRHGERDVEVERWRERVTQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLSSWLQDAKSRQEQIQAVPIANSQAAREQLRQEKALLEEIERHGEKVEECQKFAKQYINAIKDYELQLITYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTRYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAELEARELQRRMQEEVTRREEAAVDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVRLQLETTERQRGGAEDELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEAELALRVKAEAEAAREKQRALQALDELKLQAEEAERWLCQAEAERARQVQVALETAQRSAEVELQSKRPSFAEKTAQLERTLQEEHVTVTQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLTEGTAQQRLAAEQELIRLRAETEQGEHQRQLLEEELARLQHEATAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEARRHRELAEEDAARQRAEADGVLTEKLAAISEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASESELERQKGLVEDTLRQRRQVEEEIMALKASFEKAAAGKAELELELGRIRSNAEDTMRSKELAEQEAARQRQLAAEEEQRRREAEERVQRSLAAEEEAARQRKVALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFVVQQREEELQQTLQQEQNMLERLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRVQMEELGKLKARIEAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQADKEQMAQQLVEETQGFQRTLEAERQRQLEMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDQDAERLREAIAELEREKEKLKQEAKLLQLKSEEMQTVQQEQILQETQALQKSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAKQLQEEQQRQQQQMEQEKQELVASMEEARRRQREAEEGVRRKQEELQRLEQQRQQQEKLLAEENQRLRERLQRLEEEHRAALAHSEEIATSQAAATKALPNGRDALDGPSMEAEPEYTFEGLRQKVPAQQLQEAGILSMEELQRLTQGHTTVAELTQREDVRHYLKGGSSIAGLLLKPTNEKLSVYTALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGEQISLFQAMKKDLIVRDHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLTDKAAKGGELVYTDTEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIVITVVEEHERKGQLCFEGLRALVPAAELLDSGVISHEVYQQLQRGERSVREVAEADEVRQALRGTSVIAGVWLEEAGQKLSIYEALRRDLLQPEVAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEMHEKLLSAEKAVTGYRDPYSGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVAYARGYLDKETNRALTSPRDDARVYLDPSTREPVTYSQLQQRCRSDQLTGLSLLPLSEKAVRARQEEVYSELQARETLEKAKVEVPVGGFKGRALTVWELISSEYFTEEQRQELLRQFRTGKVTVEKVIKILITIVEEVETQRQERLSFSGLRAPVPASELLASKILSRTQFEQLKDGKTSVKDLSEVGSVRTLLQGSGCLAGIYLEDSKEKVTIYEAMRRGLLRASTATLLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEKLLSAEKAVTGYKDPYSGSTISLFQAMKKGLVLRDHAIRLLEAQIATGGIIDPVHSHRLPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLRGAEKTEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSSMSLWEVMQSDMIPEDQRARLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQNLASYDYVRRRLTAEDLYEARIISLETYNLFREGTKSLREVLEMESAWRYLYGTGSVAGVYLPGSRQTLTIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQPISLFQAMKKELIPAEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYVDPSTDERLSYTQLLKRCRRDDNSGQMLLPLSDARKLTFRGLRKQITVEELVRSQVMDEATALQLQEGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIGDAITKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSSYPISSAVPRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTEAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVSLDEALQRGTVDARTAQKLRDVSAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSSKGYYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGPSASLGGPESAVA",
    "output": "Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. May be involved not only in the cross-linking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLYDDKYLAIANDILENGYFDNNRTGVKTYKLPHQIMQFNLEKEFPILTTKFVAFKTAVKELLWIFKDQSNSVKELQSQNVKIWDEWMMEDGTIGTSYGWIVKKFDQIDKLIDALKNNPQDRRMMINLWQIPYLDSAPLYPCCFLTMWDVTDGKLNCMLVQRSGDWGLGVPFNTSQYAVLVHLLAQVTGLKPGLFTHVINNAHIYENQVDGLKLQLTRKNDAYNAPKLWINPEITNFYDFTPDDIKLEDYKHHESIKMDVSV",
    "output": "Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLSVEMISRQNRCHYVYKGGNMMRRILHIVLITALMFLNVMYTFEAVKAAEPQQPISIEKAIQQKEGQALVEGYAVGQAVSPQHYKLTSPFSNDYNVALADRKNKTSPEHILPVQIPSAFRSQFGLQTNPLLLGKKITVQGKLENYFNTTGLKNVQSMNVTDDTKTPPAEQQVTINEARGRLNEEVTIKGIITADQNAIGGGKLSTFLQDETGGINIYSPSPEQFPELKEGMDVTVTGKITSYQGLKEIVPNSSGIKINQSNQSLPAPKHLTINELINGSLGDQYEGRLVKLTAFVSSIPSSPAGGGYNVTMIDDDHHAMTLRVMNETGVINELDEGKWYEFTGVLSRYQTFQLLPRKSADLKLLEEQPAPPSAEGEYEGIVDRVVDGDTIHLKSPVLGTTKIRFVNVDAPETYHTPKNDADENQLRFGKKASDYLKTVLSPGDKITVKVGSEAKDSYGRLLGQVITESGSNVNLELVKNGYAPTYFIWPVDNEEDYQQFQAAVAAAKKDQKGIWNENDPLMEMPFEFRAREQGKGLTRYVGDSSNKTYVQPADWKKIAVENRIFFASASEAESAGYKKRQTAPQEHVPLRILSMNDLHGKIDQQYELDLDGNGTVDGTFGRMDYAAAYLKEKKAEKKNSLIVHAGDMIGGSSPVSSLLQDEPTVELMEDIGFDVGTVGNHEFDEGTDELLRILNGGDHPKGTSGYDGQNFPLVCANCKMKSTGEPFLPAYDIINVEGVPVAFIGVVTQSAAGMVMPEGIKNIEFTDEATAVNKAAEELKKKGVKAIAVLAHMSAEQNGNAITGESADLANKTDSEIDVIFAAHNHQVVNGEVNGKLIVQAFEYGKAIGVVDVEIDKTTKDIVKKSAEIVYVDQSKIEPDVSASAILKKYETIAEPIISEVVGEAAVDMEGGYSNDGDTPLGNLIADGMRAAMKTDFALMNGGGIREALKKGPITWGDLYNIQPFGNVLTKLEIKGKDLREIINAQISPVFGPDYSISGFTYTWDKETGKAVDMKMADGTEIQPDATYTLTVNNFMATATGAKYQPIGLLGKNPVTGPEDLEATVEYVKSFDEPIAYTKEGRIKLAEASDIEDPVTEDPITEEPGDDPGTEDPIKEDPRPGEDLPDIKETPGTAPVHQLPPSAISRFNEIPINNTKTADTANSISTLPLQTETAESGSDHQLPDTSAGYYNFMVIGAAVTLSGTYLYVRRKRSASRT",
    "output": "Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected, using 5'-AMP as the substrate, in the presence of diverse divalent metals and with various pH values."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MANPIKIGIGGPVGAGKTQLIEKVVKRLSKEMSIGVITNDIYTKEDEKILVNSGVLPESRIIGVETGGCPHTAIREDASMNFAAIDELLERHDDIELIFIESGGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSDFFVINKTDLAPYVGASLEQMAEDTKVFRGKRPFTFTNLKTDEGLDEVIDWIERDTLLKGLS",
    "output": "Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPSSGRALLDSPLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF",
    "output": "Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNPIVVVHGGGAGPISKDRKERMHQGIVRAATVGYGILREGGSAVDAVEGAVVALEDDPEFNAGCGSVLNTDGEVEMDASIMDGKDLSVGAVSAVRCIANPIKLARLVMEKTPHCFLTDQGAAQFAAAMGVPEIPGEKLVTEKNKKRLEKEKHEKGAQKTDCEKNLGTVGAVALDFKGNVAYATSTGGIVNKMVGRVGDTPCVGAGGYADNDIGAISTTGHGESILKVNLARLTLFHIEQGKTVEEAADLSLGYMKSRVKGLGGLIVVSKTGDWVAKWTSTSMPWAAAKDGKLHFGIDPDDTAITDLP",
    "output": "Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKTDRHKKILEVIDRYEVGTQEELAKILNDEGYNVTQATVSRDIRELNLSKVSVDGKRTRYATLTKDKPVASDKFLTVLKEGFVSMDMAQNILVIKTAPGMAMAVCAAIDALEWNEIVGSIAGDDTIMCAVRTVNDTLLVMNKIKKLIKNN",
    "output": "Regulates arginine biosynthesis genes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "VSLREQWNEQARERQREISARKTEIEEARSSIQKELQAQYEAALAATQQLQSLXXRFXRFY",
    "output": "May confer stability to the gas vesicle membranes. Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MALTSEQKKEILSSYGLHATDTGSPEAQIALLTKRIADLTEHLKVHKHDHHSRRGLLLLVGRRRRLIKYLSLIDVQRYRSLIERLGLRR",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFSFEKNSLKNTDKEIFDAIELEVKRQHEHVELIASENYASPAVMEAQGSQLTNKYAEGYHGKRYYGGCEFVDIAEKLAIERAQQLFGVDYANVQPHSGSQANAAVYNAVLKPGDTVLGMDLGAGGHLTHGSKVNFSGKIYNSIQYGLDENGDIDYEQVAQLAKEHKPKMIIAGFSAFSGIINWQKFREIADSVDAVLMADIAHVAGLVAAGVYPNPFPYVDVATTTTHKTLRGPRGGLILCNNNPELAKKFQSAIFPGIQGGPLMHVIAAKAVAFKEALEPSFVDYQKQVLKNAKAMEKVLKQRGINIISGGTSNHLLLLDITNTGFSGKEAEAALGRANITVNKNSIPNDPRSPFVTSGLRIGSPAITTRGFKEKECELVANLLADVVFNCGDEKVENETAAKILDLCDKFPVYK",
    "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNQLYQRSFLRLMDFSMNEIMYILRLSHFLKQQKSNHTETQKLHKKNIVLIFENHSTRTRCAFEVAAFDQGARVTCLTPNISQIGHKESIKDTAKILGRMYHGIQYRGYNQDTINIFAQYSNVPVWNGLTEQFHPTQMLADLMTMQEQVPHKSFCKIKLAYVGDARNNIGNSLLEAASIIGFDLRLVSPREFWPQQELLTTCRKLTKLNKVNILLTENIQEGVKDVDFLYTDVWVSMGENEKVWTHRISLLSPYQVNQDMINYTGNSNVKFLHCLPALHNNETTIGKKIAHKHNLFNGLEVTNEIFESKHSIVFDQAENRLHTIKALMISTLLPNLYHKNITFHTKN",
    "output": "Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKKSKIVKNNKRRDIVARYAQRRAELKQIIQSPTSSYEQRLDAQRALSRQPRDASAVRLRNRDAIDGRPRGHLRKFGLSRVRVRELAHAGQLPGVRKASW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLGDGNEGISTIPGFNQIQFEGFCRFIDQGLTEELYKFPKIEDTDQEIEFQLFVETYQLVEPLIKERDAVYESLTYSSELYVSAGLIWKNSRDMQEQTFFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTGTIISDWGGRSELEIDRKARIWARVSRKQKISILVLSSAMGLNLREILENVCYPEIFLSFLSDKERKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGRIGRRNMNRRLNLDIPQNNTFLLPRDILAAADHLIGLKFGMGALDDMNHLKNKRIRSVADLLQDQFGLALVRLENVVRGTICGAIRHKLIPTPQNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHAKIGHWGSLESPFYEISERSTGVRMLYLSPGRDEYYMVAAGNSLALNRDIQEEQVVPARYRQEFLTIAWEQVHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQAALDSGALAIAEREGRVVYTNTDKILLAGNGDILSIPLVIYQRSNKNTCMHQKLQVPRGKCIKKGQILADGAATVGGELALGKNVLVAYMPWEGYNSEDAVLISERLVYEDIYTSFHIRKYEIQTHVTSQGPEKVTNEIPHLEAHLLRNLDKNGIVMLGSWVETGDILVGKLTPQVVKESSYAPEDRLLRAILGIQVSTSKETCLKLLIGGRGRVIDVRWIQKRGGSSYNPETIRVYILQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRSVDMVFNPLGVPSRMNVGQIFECSLGLAGSLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGNPFEQPVIIGKPYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGGTIPNPEDAPESFRLLVRELRSLALELNHFLVSEKNFQINRKEA",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTNELPEIGSPARTKAILNRYRLVAKKSLGQNFLSDLNILRNIVAAGDVNDHDNVIEIGPGIGALTEQIAKRAHKVVAFEIDENLLPVLDETLMDYKNVKIINEDILKANLPAVVADEFEADRPLKLVANLPYYITTPILMGVLQSTVRFEAIVVMMQAEVAERLVAEPGTKAYGSLSVIMQYRAHVEIAFNVPRTAFIPQPNVDSAIIRLTPREALPVNPYEDKALFSFVKGCFAHRRKSLWNNLQGIFGKQPEVRERIETVLNQTGISRQLRPERLTLLNFIELTNAFHNEGLM",
    "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "METQKDEAAQAKGAAASGSTREQTAEKGAKNKAAEATEGPTSEPSSSGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKGSGKGSSKKGLSKSKTHDGLSEAAHGPEDVVSEGTGFSLPLPELPCQFPSSQSAHGALETGSRCKTSVAGATEKAVAEKFPSMPKPKKGLKGFFSSIRRHRKSKVTGAEQSEPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVSPTPEPSPPATEKMACKDPEKPMEACASAHVQPKPAPEASSLEEPHSPETGEKVVAGEVNPPNGPVGDPLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTTSPGHHGYMLLDPVRSYPGLAPGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALGLVRRDCLPRDSYSGDALYEFYEPDDSLENSPPGDDCLYDLHGRSSEMFDPFLNFEPFLSSRPPGAMETEEERLVTIQKQLLYWELRREQLEAQEARAREAHAREAHAREAYTREAYGREAYAREAHTWEAHGREARTREAQAREVRCRETQVRETQARQEKPVLEYQMRPLGPSVMGLAAGVSGTSQISHRGITSAFPTTASSEPDWRDFRPLEKRYEGTCSKKDQSTCLMQLFQSDAMFEPDMQEANFGGSPRRAYPTYSPPEDPEEEEVEKEGNATVSFSQALVEFTSNGNLFSSMSCSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENPEFHNDEDLAASLEAFELGYYHKHAFNNYHSRFYQGLPWGVSSLPRYLGLPGLHPRPPPAAMALNRRSRSLDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLSLYTEPPGAYDWPAWAPCPLPVGPGPAWISPNQLDRPSSQSPYRQATCCIPPMTMSISLSVPESRAPGESGPQLARPSHLHLPMGPCYNLQPQASQSMRARPRDVLLPVDEPSCSSSSGGFSPSPLPQAKPVGITHGIPQLPRVRPEHPQPQPTHYGPSSLDLSKERAEQGASLATSYSSTAMNGNLAK",
    "output": "Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. Acts both as a positive and negative regulator of the Wnt signaling pathway, depending on the context: acts as a positive regulator by promoting LRP6 phosphorylation. Also acts as a negative regulator by acting as a scaffold protein for the beta-catenin destruction complex and promoting stabilization of Axin at the cell membrane. Promotes CTNNB1 ubiquitination and degradation. Involved in kidney development."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSVEAVVKQVDGDALEAAIKGDKLLVCDFFATWCGPCKSLAPKLDAMAKENEKVIFVKLDVDECQDVAEKYRVTAMPTLIVFKNGCEIGHVVGANEAGIRELIQANA",
    "output": "Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPRSQRNDNFIDKTFTVVADILLKVLPTTRREKEAFTYYRDGMSAQAEGEYAEALQNYYEAMRLEVDAYDRSYILYNIGLIHTSNGEHAKALEYYYQALERNPYLPQALNNIAVIYHYRGEQAIESGNSRISNLLFDKAADYWKEAIRLAPTNYIEAQNWLKITNRLEEAI",
    "output": "Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQQFYCVKEVLNERLKRGYEFAVKNEYIEEKVTEKLQGIAATARMDGFRKGKVSPEFVRRMYGESIAGEVVAQVIDDISSKFLKEGDFGGIVTSGVEIKAYPKVCSNSEGDGGLVYELKFEVMPEVPVVDIDGITLKEIEVNISQEDVDEFLEDLKANYPSFVDVDDESRGVSDGDRVTISYRSAFKGKALRGGSAQGFTFVLGKGQLLEQFERQIVGMKKGESKEFKLEFPLDYMAKHFAGKEVDMHVTVERLSVKDEINDRETLASKCGFGSVEDMVKFATDGLNRRFADMGSVVAQRELLEHLDASYSVDVPEYIVAQELGRMRRELEEGDLNDAEALTKEAEQRVKLGMLLMKVATDAGVAVEVNDILSFIRVNYSAYGRSMEDVLKLFKNREDFREHVKGKVLEDKVVRYIISRAKKDRQSMSAGELKSLFESV",
    "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTQDVTSGYSNLDLDLRDNGVCVVTLNRPDKRNALDVATIEELVTFFSTAHRKGVRAVVLTGAGDHFCAGLDLVEHWKADRSADDFMHVCLRWHEAFNKMEYGGVPIIAALRGAVVGGGLELASAAHLRVMDQSTYFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAADLGLAQYITEGSSFDKAMELADKIASNLPLTNFAICSAISHMQNMSGLDAAYAEAFVGGIVNTQPAARERLEAFANKTAARVRPNS",
    "output": "Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by catalyzing both the hydration and the hydrolysis of 3-(methylthio)acryloyl-CoA (MTA-CoA) to acetaldehyde, CO2, MeSH, and CoA ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA",
    "output": "Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNLNDDDDNYNSAIVIDNGSYLCKAGFGGEESPRAIFRSVVGRPNFCTRGVKNGMGQKDCYVGDEAIVKKSILSLKCPNESKSPVNWDDIEKILHHVFYNELRVTIDKGVLLSEIPLNPKENRERITQIMFETFDTPNFYLANQSVLSLYSKGRLNGIVLDSGNNITYTVPIYEGHSIPNSINQLEIAGNSVTEYLMKILNENRGYNFTTSSEKEIVKDIKEKFGFISLNYNNDLYSTKVATNEIEKSYQLPDGQMITIGKERFICGEVLFEPSLVNIESYGVHQLLYNSIINCDFEIRRGLYNNIILSGGTTMLPDFNDRIKNELINLSPSSMKIKVVENNTNENNSHLAWIGGSIFSSLSTFEQQSISKQEYMEYGSKIIQRKCF",
    "output": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVKIGVLGLQGAVREHVKSVEASGAEAVVVKRIEQLEEIDGLILPGGESTTMRRLIDKYAFMEPLRTFAKSGKPMFGTCAGMILLAKTLIGYEEAHIGAMDITVERNAFGRQKDSFEAALSIKGVGEDFVGVFIRAPYVVNVADDVEVLSMHGERMVAVRQGPFLAASFHPELTDDHRVTAYFVEMVKEAKMKKVV",
    "output": "Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHMIYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFISIETKDPLRFPGYQEKLQKAKETTGLHEAVLTGKAMVKGQQIALAIMDSHFIMASMGTVVGEKITRLFELAIEENLPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFAMEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDKIAHLVAFHGGGQ",
    "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEDTLSLAEAMEDLVSAEDFLDYFAVPYDPAVVHVNRLHILQRFHDYLAKQAPNLPPEESQQRGIYRLWLERAYQDFVTSDSLTEKVFAVFQTVSKPDGGMSSFVSLDKVFRQ",
    "output": "May protect the nitrogenase Fe-Mo protein from oxidative damage."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKFNRMHLIVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISKTVGLNVPNMAKLGLGNIPREQPLKTVPAESNPTGYATKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEILTQIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDIIPVEELYRICEFARSITLERPALLGRIIARPYVGEPGNFTRTSNRRDLAISPFAPTVLDKLNEAGIDTYSVGKISDIFNGEGINHDMGHNKSNNHGVDNLIKAMTSEDFKHGFSFTNLVDFDALYGHRRNPQGYRDCLHEFDERLPEIIAAMKEDDLLMITADHGNDPTYAGTDHTREYIPFLAYSPSFKCSGLIPVGHFADISATIADNFGVEKAMIGESFLDKLV",
    "output": "Phosphotransfer between the C1 and C5 carbon atoms of pentose."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNATNNQSTQVSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVSTDTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK",
    "output": "Cell wall-anchored surface receptor that participates in the extraction of heme from oxidized methemoglobin/metHb to enable growth on hemoglobin as a sole iron source (By similarity). Receives heme from IsdB and transfers it to IsdC (By similarity). Also plays a role in the inhibition of host immune response. Protects S.aureus against the bactericidal protease activity of apolactoferrin. Decreases bacterial cellular hydrophobicity, which renders S.aureus resistant to bactericidal human skin fatty acids as well as to beta-defensins and cathelicidin. Also binds fibronectin and chains B-beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTSVHSLGFPRIGHKRELKKALESFWSREIDEQELQSRAAQLRDRHWRIQQTCGMDLVPVGDFSLYDHMLDMSCTLGAIPPRYGFAGGQVGLDTFFAMARGSATQPAMEMTKWFDTNYHFIVPEFHEGMDFRLSSERLFDQVKEVQALGLKAKPVLVGPITYLWLGKEKDLNAEAHHDAQHHHDDSACHGHGAPIGAACFDRLTLLPKVLPVYAEILARLAEMGVEWVQIDEPALALDLPQEWVEALESAYQTLRRDKTPKVLLATYFDSVADHAKALKALPVAGVHLDLRRAPQQLNSFLSDYPADKVLSLGVVDGRNVWRADLDAALELLQPAHKQLGDRLWVAPSCSLLHTPVDLEQETELDAELKSWLSFSVQKLDEVAIIGRALKEGVESVAQELAAARAAVASRKSSPRIHNPAVAQRLEGLGQDDGRRKSPFPIREAAQRARFKLPAFPTTSIGSFPQTPEIRKARLQNRKGELSNADYQKAMEAEIALVVKEQERLGIDVPVHGEPERNDMVEYFGEQLAGFAFTRHGWVQSYGSRYVKPPLIFGDVSRPTPMTVAWSKYAQSLTQRPMKGMLTGPVTILQWSFVRDDQPRERTALQIALAIRDEVRDLIDAGIGIIQIDEPAYREGLPLKRKDWGHYLEWASRAFRISAQIAPDDVQIHTHMCYSEFNDILPAIAAMDADVITIETSRSQMELLDAFATFNYPNEIGPGVYDIHSPRVPSVEEMVGLMEKAVKVVPAERLWINPDCGLKTRKWAEVTPALENMVEAARQVRARHG",
    "output": "Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPPAALQATVSESVKDAIISKLRQPPSAVPSREWSAETRTSLTPADAGIAEARASAEDIELVDLQHHNFSEPRKRIVSPASLSRFEHSQAFAEILAFICVCNTRVVGKTLTEEIQISSACRTILEMLDQVAALRESTPPDASIGSSRFGNPAFRTFYAKIRENTDRLHRMIPGLETDSEWSRAARAELSVYFQECWGNEKRIDYGSGMELNMACWLLCLCKLRILRLPEDGACIVLRIFWTYVQVMRDIQSSYWLEPAGSHGVWGLDDYHFLPFLWGAGQLSSHRHLRPKAIHDAEIVDEFAPKYMYLACIQFINSVKTASLRWHSPMLDDISGAKSWSKVNQGMIKMYRAEVLKKLPIAQHIFFGSLLRFPEPATGELEEEDVEEDAHGHIHPAGKPHAHGTGEGQAAGWGDCCGIPIPSAFAAAEQEKKRQQGNFSSTMLGEKPFGTGVRRIPFD",
    "output": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQPLTKDAGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRNDSSDYVVCPWSALLSAAGSLSFQGRVSHIEAAPFKAPELLQGQSEDEQPDASQMHVYSLGMTLYWSAGFHVPPHQPLQLCEPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAPAGLHIRRLVGLVLGTISEVEKRVVEESSSVQQNRSYLLRKRLRGTSSESPAAQAPECLHPCRVSERSTETQSSPEPHWSTLTHSHCSLLVNRALPGADPQDQQAGRRLSSGSVHSAADSSWPTTPSQRGFLQRRSKFSRPEFILLAGEAPMTLHLPGSVVTKKGKSYLALRDLCVVLLNGQHLEVKCDVESTVGAVFNAVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIAPEGWREQPQKTSMNTFTLFLRIKFFVSHYGLLQHSLTRHQFYLQLRKDILEERLYCNEEILLQLGVLALQAEFGNYPKEQVESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELKFLRVTQQLPEYGVLVHQVFSEKRRPEEEMALGICAKGVIVYEVKNNSRIAMLRFQWRETGKISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMGSGQPSHVLFDHDKFVQMANLSPAHQARSKPLIWIQRLSCSENELFVSRLQGAAGGLLSTSMDNFNVDGSKEAGAEGIGRSPCTGREQLKSACVIQKPMTWDSLSGPPVQSMHAGSKNNRRKSFIAEPGREIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSKGVGGNNPDEEKNSTANSGVSSTDILSFGYQGSLLSHTQDQDRNTEELDMAGVQSLVPRLRHQLSFLPLKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVPRSTQQCPSANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESSQKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCDIMRLGRYSFSSPLTRLSTDIF",
    "output": "May play a role in the regulation of tight junction formation. Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGPQQDRSAAKPYANGSTAAAAAAGRKENNKVVRYRECQRNHAASIGGHAVDGCREFMASGADGTAAALLCAACGCHQSFHRREVEAAAAECDCSSDTSSGTGRR",
    "output": "Inhibits zinc finger homeodomain (ZHD) transcription factors, by interacting with them to prevent both their nuclear localization and their DNA-binding properties."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKGQRIRIKLQGFDYRVIDQSALEIVETAKRSGARVSGPIPLPTRVEKLSVNRSPHVDKKSMEQFETRTHKRLIDIIEPTAQTVDELKKLNLPSGVDITINV",
    "output": "Involved in the binding of tRNA to the ribosomes."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "DILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEFEAMDTL",
    "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSLPQDLLYSKEHEWVKQEDGKLRIGITDFAQDELGDIVFVELPEIGEELKVDDPFGSVESVKTVSELYAPVSGKVVEINDDLEDSPEYVNESPYEKAWMIVIEPSDEKELEELLSAENYEAFIQD",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKKIKSFGGKNLGGGKQEKLLKDFAKMQEELQKKIQELEESFSQIEVEASVGGGAVRIVATCDRRVKDIEIDEDLKEDFDTLKDLLIAGMNEVMEKIEKRREEEMSKITQQFGIPGLM",
    "output": "Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLSAFKLHNNRLSRLELDESDDLASSLWVDLVEPEEGERERVQTELGQSLATRPELDDIEASARFFEDEDGLHIHSFFYYEDADDHAGNSTVAFTIRDGRLYTLRERELPAFRLYRMRARNQTLVDGNAYELLLDLFETKIEQLADEIENIYSDLEALSRVIMEGQQGDEYDAALSTLAEQEDIGWKVRLCLMDTQRALNFLVRKARLPSSQLEQAREVLRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELRWSFGYPGAIALMIIAGLAPYLYFKRKNWL",
    "output": "Mediates influx of magnesium ions (By similarity). Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSTINTDANEAMPHISVNAQYIKDLSLENPDAPSSLAALEHRPQIDLSLDINITNLSEENFYEVELNIEAVARNEKYKLFQVELKYAGVFNLINIAPEQHQILLSVHCPAMIFPFARKIIASCTQDAGFQPLMIDPIDFGALYHKKMSEHQN",
    "output": "One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKTRFDVVLLGIDKAGQWHVNDAENYLQNADDPAHIALRPSAISLAQVPGKHQHQLINAQNGQPLPTVDVIFPIVHGTLGEDGSLQGMLRVANLPFVGSDVLSSAACMDKDVAKRLLRDAGLNIAPFITLTRTNRHAFSFAEVESRLGLPLFVKPANQGSSVGVSKVANEAQYQQAVALAFEFDHKVVVEQGIKGREIECAVLGNDNPQASTCGEIVLNSEFYAYDTKYIDDNGAQVVVPAQIPSEVNDKIRAIAIQAYQTLGCAGMARVDVFLTADNEVVINEINTLPGFTNISMYPKLWQASGLGYTDLISRLIELALERHTANNALKTTM",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSDIEAPTSLTSMRGALPPAVADDVRALHLTTVRHDGVPPLSEQPLLWLSDQEAPVVHVLAWHAVTGGAQELVGYAQVDVGSSTTARAELVVAPGHRRRGTGRSLLAHAAQEAASIPGRRLHVWAHGDLPAARATAAATGLVVVRELWRMAVDVTQHPPGAPQLPPGVAVRAFVPGQDEDAWRRVNARAFAHHPEQGRMTSADLRARESEPWFDPAGFLLAERDGQLLGSVWTKVHPGSEAPDGAPGEEVGEIYVVGVDPDAQGLGMGRALTALGLAHLRDRGLRTVILYTGAENTVAVHTYRRAGFARTAVDVMYGPPPAGSPAHGTPLVRVTDTPSSPGDATMGS",
    "output": "Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFEVKMGSKMCMNASCGTTSTVEWKKGWPLRSGLLADLCYRCGSAYESSLFCEQFHKDQSGWRECYLCSKRLHCGCIASKVTIELMDYGGVGCSTCACCHQLNLNTRGENPGVFSRLPMKTLADRQHVNGESGGRNEGDLFSQPLVMGGDKREEFMPHRGFGKLMSPESTTTGHRLDAAGEMHESSPLQPSLNMGLAVNPFSPSFATEAVEGMKHISPSQSNMVHCSASNILQKPSRPAISTPPVASKSAQARIGRPPVEGRGRGHLLPRYWPKYTDKEVQQISGNLNLNIVPLFEKTLSASDAGRIGRLVLPKACAEAYFPPISQSEGIPLKIQDVRGREWTFQFRYWPNNNSRMYVLEGVTPCIQSMMLQAGDTVTFSRVDPGGKLIMGSRKAANAGDMQGCGLTNGTSTEDTSSSGVTENPPSINGSSCISLIPKELNGMPENLNSETNGGRIGDDPTRVKEKKRTRTIGAKNKRLLLHSEESMELRLTWEEAQDLLRPSPSVKPTIVVIEEQEIEEYDEPPVFGKRTIVTTKPSGEQERWATCDDCSKWRRLPVDALLSFKWTCIDNVWDVSRCSCSAPEESLKELENVLKVGREHKKRRTGESQAAKSQQEPCGLDALASAAVLGDTIGEPEVATTTRHPRHRAGCSCIVCIQPPSGKGRHKPTCGCTVCSTVKRRFKTLMMRRKKKQLERDVTAAEDKKKKDMELAESDKSKEEKEVNTARIDLNSDPYNKEDVEAVAVEKEESRKRAIGQCSGVVAQDASDVLGVTELEGEGKNVREEPRVSS",
    "output": "Transcriptional repressor of gene expression involved in embryonic pathways, such as LEC1, ABI3, and FUS3. Repressor of the sugar-inducible genes involved in the seed maturation program in seedlings. Plays an essential role in regulating the transition from seed maturation to seedling growth. Functionally redundant with VAL2/HSL1."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDKEEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKENGIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFDDLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNEVDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQGLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK",
    "output": "Acts as a chaperone."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEEFQGYLELDRFRQHDFLYPLIFREYIXXXAHDHGLNRVILLENLAYDNKSSLLIVKRLITRMYQQNHLMISANDSNQNRFLGYNKNLYSQMISEGFSIIAEIPYSLRLISSLEGAQIIRSYNLRSIHSIFPFLEDKFPHLNYVADVLIPYPIHLEILVQTLRYRVKDASSLHLLRFFLHEYSNGNILFILNKSISIFSKSNSRLLLFLYNSYICEYESLFLFLRNQSSHLRLTSSGVLFERIYLHRKMGDLAEVFVNDFRGILCFLKDPFIHYVRYQGKSILSSKDTPLLMNKWKYYLVSLWQCHFYVWSHPGRIYINQLSKHSLDFLGYFSNVPLNPSMVPSQMLENSFVINNAPKKLDTIVPIIPLIGSLAKAKFCNALGHPISKPTWADLSDFDIINRFVRICKNLSHYYSGSSKKKGMYRIKYILRLSCVKTLARKHKSTIRAFLKRLGSELFEEFFTEEEEFLSLIFPRTSFTLRRLYRGRVWYLDIICMNGLANHE",
    "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTQPAIYLDNNATTRVFPEVVAAMLPYFTEHFGNASSGHGFGAQAGLGLRKARLAVAALIGAASEQEILFTSGGTEANTTAIRSALAVQDGRREIIISAVEHPAILMLAADLEKTEGVRVHRIPVDHLGRLDLAAYRAALSDRVAVASIMWANNRYDLPVPQLAAEAHAAGALFHTDAVQAVGKLPMSLADTEIDMLSLSGHKFHGPKGVGALYLRKGVAFRPLLRGGKQERGRRAGTENVPALVGMGLAAEIVAARMAADLSRIATLRDWLESGILALGGCQRLGDPANRLANTCTLAFDRIDSEAVLTKLARAGIAISTGSACASGAMEPSHVTRAMAVPFTAAHGVVRFSLSADTTAAELSRVLAILPEILAELRPVPVTA",
    "output": "Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKASRFFIGTLKEAPADAEIVSHKLMVRAGMIRRVAGGIYNYLPVGLRSIRKVEAIVREEMNRAGAIELLMPAVQPAELWQESGRWEQYGPELLRFKDRKQNEFVIGPTHEEVVTDIARNQIKSYRQMPVNFYQIQTKFRDEIRPRFGVMRGREFIMKDAYSFDKDHESLKESYKKMYDAYVRIFTRIGLEFRPVAADNGSIGGSGSHEFHVIADTGEDAIAYCPTSDFAANVEAAEALPLLASRAAPAEAMQKVATPGKAKCEAVAELMGIPLERTIKSIVLATDNEGAEPTIWLLMLRGDHDLNEIKTAKLPGLAGHRFATEAEIVEWFGTPPGYLGPIGTKKPVRVVADRTVANMSDFVVGANEVDYHIAGVNWGRDLPEPVVADIRNVKAGDPSPDGKGALDICRGIEVGHVFQLGTKYSDAMGATFIDESGKAQPMVMGCYGIGITRILGAAIEQNFDDKGIVWPEAIAPFEVVLCPMGYDRSDAVREAADKLYADLAAAGIDVILDDRGERPGVMFADWELIGVPHRLVIGERGLKDGKIEYQGRRDAEATLLPADSAAAAVAEKVRAALAR",
    "output": "Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSGRASLSSLLGGAPPWGSLQDPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVMGSLGKHAAPSAFSSGLPGALSQVAVTTLTRDSGAWVSHVANSVGPGLANNSALLGADPEAPAGRCLPLPPSLPVCGHLGISRFWLPNHLHHESGEQVRAGARAWGGLLQTHCHPFLAWFFCLLLVPPCGSVPPPAPPPCCQFCEALQDACWSRLGGGRLPVACASLPTQEDGYCVLIGPAAERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK",
    "output": "Probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPLQIFNTTRKELHEELLERTVIDVLDSEGFGVESIVAVYCGKKMIRKINREFLQHDYATDTITFRYSDNREIDGEFYISLDVIEENARRFEVDFKLELLRVTIHSALHLIGYDDQTVDGRLQMQQKEEFYLNRYSEANNQTPS",
    "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MYQRPQNDYLRVNKRKSNYDQLNADSNSVPQLAQTQPRVQVYIIDKNDFKSLVQQLTSPQPCDRLPQNIPKHQDIRPEPINWTSSIPPSAMAVQEDPDVSLYMAYLQSLLEESSGSNGDQFEEPFDKYHSHMMAQSQPQDPTQSMPQSNGFEPFPSSWFNGSTQEMHGASSLQSTRVDYEYPLPLTPNFTFSSMTQHEVFGSDLDSIGPDEDLEFSYEIN",
    "output": "May function as negative regulator of plant defense."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKSGIYLGCFILILIQNMVAANPLFNRNNVQELENLKDLIHQLEERVAVNEEPEVYPESEDMKMDAEEEDAGISPGALRQSEENLLMNIVDRIAPESPLRSRFRDLAGLAKTAKSFNSCFGTRMDRIGSWSGLGCNSLKNGTKKKIFGN",
    "output": "Exhibits natriuretic and vasodepressor activity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSDRLTLLRPDDWHIHLRDGAVLPHTVGDVARTFARAIIMPNLVPPVRTANEAGAYRERILAARPAGSRFEPLMVLYLTDNISPEDIRAAKASGFVYAAKLYPAGATTNSDSGVTSIDNIFPAIEAMAEVGMPLLVHGEVTRSEIDVFDREKRFIDEHMRRVVERFPTLKVVFEHITTSDAAQFVTEAPANVGATITAQHLLYNRNHMLVGGIRPHFYCLPILKRNTHQVALLDAATSGNPKFFLGTDSAPHARHAKEAACGCAGCYTAYAAIEMYAEAFEQRNALDKLEGFASLHGPAFYGLPANTDTITLVREEWTAPESLPFGEQTVVPLRAGEKLRWRLLEKNA",
    "output": "Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNHIDFGFKKVDYTKKQGLVNSVFSNVADKYDLMNDLMSFGLHRLWKDEFIRRIPNLNSHILDVASGSGDIALKLAKKARDRGNNIALTLSDINEEMLKNAKKKTIDLNLFQNLKFTVASAEELPYPDNSFDYYTIAFGIRNVPDINKALKEAYRVLKPMGKFICLEFSKVKESYFKDFYKFYSFSIIPTIGQVITGNKEAYEYLVESIELFPSQDEFRIMIKEAGFEEVGYKNLSGGIVAIHSGYKI",
    "output": "Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIRYLRGLVLKKEAGGFVLLAGGVGFFLQAPTPFLQALEEGKEVGVHTHLLLKEEGLSLYGFPDEENLALFELLLSVSGVGPKVALALLSALPPRLLARALLEGDARLLTSASGVGRRLAERIALELKGKVPPHLLAGEKVESEAAEEAVMALAALGFKEAQARAVVLDLLAQNPKARAQDLIKEALKRLR",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEKPIVAIVGRPNVGKSTLFNKLIGERRAIIADEAGTTRDRQYGETIWNGRVFTIVDTAGLLVGDDDPNLPLAEIVRRTHQQAQLAIDEADVIVFMVDVREGLIAADEEVAALLRRSSKPVVLGVNKADTEDRRQNAVEFYNLGLGDPIALSAYHGTGSGDLLDEIVRHLPAGQEEEEDDNSLKIAIVGRPNVGKSSLLNKLVGEERVVVSNIPGTTRDSIDTKLTYKGIPITLIDTAGIRRRGSIEQGIERYSVLRTMKAIERCHIALILVDAQEGPTAQDTHVAGMVLEANKGLAIIVNKWDLIDKAKFSYEDAKTTMSQVFHFAPYAPIEFISAKTGQRATKVLDIAQTIQSERNKRVSTSDINNLLRAAVREHPPTAMHKGAHLRLFYATQAQVEPPVFLFFSNAPEQVHFGYKRYLENRIREQYGFIGTPIILVFKGREEEQTVSVSGKR",
    "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSPITLDLTSDFNPANTTGAGSSSSQPRTLLVAPPSVASHEERISALFSTYPRDTTDLHMLDRLAAGLVTLPTSTYDLILVLTDPDGSRHAEASALLSNRAVWSLLVPALKAGGKLRSEDGTLGRDTTTPEAREAVLAGLVAGADGFTKPDYAEEEAVPLRFGLKRKTNPNPVVAPIQPVAQVVTAAPAGVGFVTLDLNDDLDLDGEDDDDDVIDEDTLLTEADLRRPIQQPPECQPKPGKKRRACKDCTCGLAERLEAEDKARRDKADQALNTLKLKSEDLLELDLTVPGKTGSCGSCALGDAFRCAGCPYLGLPPFKVGEEVSILNNVPQL",
    "output": "Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex cfd1-nbp35. Electrons are transferred to dre2 from NADPH via the FAD- and FMN-containing protein tah18. Tah18-dre2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit rnr2."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNRVLYPGTFDPITKGHGDLVERASRLFDQVVIAVAASPKKNPLFPLEQRVELAREVTKHLPNVEVVGFSTLLAHFAKEQNANVFLRGLRAVSDFEYEFQLANMNRQLAPDVESLFLTPSERYSFISSTLVREIAALGGDITKFVHPAVAQALTERFKR",
    "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPNIKSAAKRVRQNKVRRLRNKSVRTRFRNVTKQLLKAIEINEEPEKVNELLRLSYSVLDKAAKKGVIHKRQASRRKSRLTAKVKAYLEARSAGSAQS",
    "output": "Binds directly to 16S ribosomal RNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKEGDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHISDANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDDYKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVETKPSVYFIKFDDDFHIYVYDLVKKS",
    "output": "May be involved in the regulation of cell cycle progression (By similarity). Exhibits H3K4me3-binding activity ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSIGKNVARLRRAKSTRLHIRKLGVPRLSVLRTGRHLYAQIFTADGSKVIAAANTLQSQVKGGLKNGKNSLAAIKVGKLIAERARAVGVDRIAFDRSGYLYHGRIKILADAARDAGLKF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEAGAYLNAIIFVLVATIIAVISRGLTRTEPCTIRITGESITVHACHIDSETIKALANLKPLSLERLSFQ",
    "output": "Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata. May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATTASNHYNLLGSGSSIVHADPGGMQQAQSYRDAQTLVQSDYTLQSNGHPLSHAHQWITALSHGDGAPWATSPLGQQDIKPTVQSSRDELHVSGTLQHQSRAPHLVHPAHGNHHGPGAWRSTGSTHLSSMASSNGQGLLYSQPSFTVNGMINPGSGQGIHHHGLRDSHDDHHGDHGHQQVSQAQQQHSQLQGGHQDHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAPEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTIPGAEDIYGASRDTPPHLGVQTSVQ",
    "output": "Transcription factor that may be implicated in patterning of the central nervous system during early development."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIRADLTDIPTYVPGKNLGDALKLSSNEVAFPPLPAAVSAITEAATGANRYPDMGAVELRGVLADHLELTPEQITVGCGSSALCQQLVQATCAAGDEVIFPWRSFEAYPIFARVAGATAVPIPLLPDTQGHDLEGMLDAITDRTRLIFLCNPNNPSGTTFTEEQFEAFMQRVPADVVVGLDEAYFEFNRAEDSPVSTEAVQRYPNVIGLRTFSKAYGLAGVRVGYAFGNPELIGAMNKVAIPFAVSSLAQAAAIASLNAADELLERTEEVVTERERVAQVVGAAPSQANFVWLPGEGAAELAGRLAEHGVVIRAFPEGARITVTNAAETDRLIRAWEAVHHG",
    "output": "May catalyze the transamination reaction in phenylalanine biosynthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "AYGEGANVFGKRKETDQFFEISGDGWSGKL",
    "output": "May be involved in the regulation of photosystem II."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRVERVLLKDYTTLGVGGPAELWTVETREELKRATEAPYRVLGNGSNLLVLDEGVPERVIRLAGEFQTYDLKGWVGAGTLLPLLVQEAARAGLSGLEGLLGIPAQVGGAVKMNAGTRFGEMADALEAVEVFHDGAFHVYCPEELGFGYRKSHLPPGGIVTRVRLKLKERPKEEILRRMAEVDRARKGQPKRKSAGCAFKNPPGQSAGRLIDERGLKGLRVGDAMISLEHGNFIVNLGQARAKDVLELVRRVQEELPLELEWEVWP",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSGIFIAIILLTILALLFGILLGFAAEKFKVEGDPLVDQLEALLPQTQCGQCGYPGCRPYAEAIANGEKINLCPPGGSATMEKLAEMAGVEPEPLSATEEVQVKKVAYIREEECIGCTKCIQACPVDAILGSGKLMHTVITDYCTGCDLCVAPCPVDCIDMLPVEQTVKNWDWKLNAIPVKTLDEDCQC",
    "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD",
    "output": "Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEEIVGLREGSPRKPVPLQELWRPCPRIRRNIQGSLEWLKERLFRVGEDWYFLVALGVLMALISYAMNFAIGRVVRAHKWLYREIGDGHLLRYLSWTVYPVALLSFSSGFSQSITPSSGGSGIPEVKTILTGVILEDYLDIKNFGAKVVGLSCTLATGSTIFLGKLGPFVHLSVMIAAYLGRVRTKTVGEPENKTKEMELLAAGAAVGVATVFAAPISGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFHLLAVFNSEQETITSIYKTSFPVDIPFDLPEIFFFVALGAICGILSCGYNYCQRTSLFFLKSNGFTSKLLATSKPLYSALAAVVLASITYPPGVGRFMASRLSMSEYLETLFDNNSWALMTKNSSPPWSAEPDPQNLWLEWCHPQMTVFGTLVFFLVMKFWMLILATTIPIPAGYFLPIFVYGAAIGRLFGEVLSLAFPEGIVAGGKVSPIMPGAYALAGAAAFSGAVTHTLSTALLAFEVSGQIVHALPVLMAVLAANAICQSYQPSFYDGTIIVKKLPYLPWIRGRKIGSHLVTVGHFMNCTLTTLAKDMPLEEVIKVVISTDVTQYPLVETTESQVLVGIVKRTHLVQSLHTDSASWAPGQQPCLQDILANGCPTQPVTLQLSTETSLHETHNLFELLNLQLLFVTSRGRAVGSVSWVELKKAISTLTNPPAPK",
    "output": "Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNDRLAARLEAEVRGEILRDEPMARHTSLRVGGPADFFVTPADPDDMRALLAILAETGTPWLAVGGGYNLLIRDGGFRGVVISSARMTSLERLEGNRAVVGAGVANGRLTAFLRNEGLAGLEFLCGIPGTVGGALAMNAGAHGGAILDRVEEILTIGTAGFECKGRELLDYGYRYLKLQPGEIIIGATFVLDSDDPRRISERIDGCRAHRTASQQVGFPNAGSFFKNPPGQAAWRLIEDAGLRGARVGGAQVSEVHTNFLVNRGGATAADFLALAARIKDAVKLKSGTALEEEVKIFGDE",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRLHLLLLILLLFSILLSPVRGGLGPAEGHCLNLFGVCRTDVCNIVEDQIGACRRRMKCCRAWWILMPIPTPLIMSDYQEPLKPNLK",
    "output": "Has antibacterial activity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MELQRAQRNLKFLQNEDYVNVTDQTNLNGESQNAYSLGMETQVPEMQFSLSSDDDSIGTQVKSVTAQKSPMTQETTKNDTERNKDVDKSCNPVSTSHPDLGGSNIEENIFINTQIQSRLDDAEEETNLKLKLEKFKYSFKSSNADDTHSNANVTAKRRPAIRKANSKLKTKPKTKRDPKIIKNITDFNINNYERSRTASLLKQLSGKHKKVLDIIKTQNEGNSDKPPRARNNKGEKATFDTYSEQEWKDIMKLLLQKFPQSEETDLNEVQKFLYGSEKSSNSLDNQESSQQRLWTASQLPPELPDEAIQPEQEERIRDTQSAVNFLSLSQVMDDKSEIMKDEESIIISRGDSTSSQEYGNGLEPQQPVGNVVGEDIELAVGTRINAFSLTDYKACKPMSVEVSRRCENSTDNDYDNISIVSDTTDETSTLFPLDQYRYVFIENDERPPLATDTIGSTQFFTPNTSPLDGIIDLTQESFKAVRSLISPLKVENNKTGVTSQASNQVQVPATRTPTIIPQKNLTTTLKTEEEKNNIGSSIRVKLLQESVVKLNPKLVKHNFYRVEANDSEEEETEFDDQFCIADIQLVDSSKISTKDSTQNPTTSNDIIDTSAASSIASPEKFCEIMMSQSMKELRQSLKTVGLKPMRTKVEIIQSLQTASQILSTANPDNKGEHGGVANFSKIEIFDHLTELIEAFPDFLERIYTFEPIPLNELIEKLFSAEPFVSQIDEMTIREWADVQGICLRNDKK",
    "output": "Regulatory subunit that interacts with and increases the activity of different structure-specific endonucleases. Has several distinct roles in protecting genome stability by resolving diverse forms of deleterious DNA structures. Component of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for simple Y, 5'-flap and replication fork-like structures. It cleaves the strand bearing the 5'-non-homologous arm at the branch site junction and generates ligatable, nicked products from the 5'-flap or replication fork substrates. Plays a critical role in maintaining the integrity of the ribosomal DNA (rDNA) loci, where it has a role in re-starting stalled replication forks. Has Holliday junction resolvase activity in vitro. Interacts with the structure-specific RAD1-RAD10 endonuclease and promotes RAD1-RAD10-dependent 3'-non-homologous tail removal (NHTR) during repair of double-strand breaks by single-strand annealing. SLX4 also promotes recovery from DNA-alkylation-induced replisome stalling during DNA replication by facilitating the error-free mode of lesion bypass. This does not require SLX1 or RAD1-RAD10, but probably RTT107."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSTSGPAAPGDVPALPPPPPGPGSGPAPPAPAATARDTMDGRAELPIFPRAGVPPLAASDTVPAVPEGAGAARPAAPPRPTSFSVLDILDPNKFNSRRRRCVLLGPVVPATCAPCAPAACVAVPAASGRSPRAELERRALSAATGVAAAAGAEPTSAGDSYRADEAEANGYSSGSGRSPTADSEDEAPEDEDEEEAPEVQDAQGTEEPRGGSGGLGARGSGCPGAAEVEASPVDDTAAPGPRGNSPGAPGPPATATGAGSAGSTPQGAAVTTKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPGAGLPGGLSPLSPSPPMGAPLALHGPAGYPAHSPGGLVCAAQLPFLSSPAVLSPFVLGSQTYGAPAFYAPHL",
    "output": "May be required for the coordinated crosstalk of factors involved in the maintenance of energy homeostasis, possibly by regulating the transcription of specific factors involved in energy balance."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGTFTLHQGQSNLIKSFFRNYYLNAELGLPNDMELREFALQPFGSDMYIRHLSFSSSEELRDYLVNRNLPLHLFYSSARYQLPSARDMEEKAWMGSDLLFDIDADHICKLRSIRFCPVCGNAITSEKCERDNVETLEYVEMTSECIKRGLEEARNLVEILEDDFGLKPKVYFSGNRGFHVQVDCYGDCALLDSDERKEIAEYVMGVGVPSYPGGSESAPGWVGRKNRGINGVTIDGQVTIDVKRLIRIPNSLHGKSGLIVKEVTNLDDFEFNEALSPFTGYTIFLPYISIETEVLSRNIKLNRGVPIKIESSIGIYLHLKNLGEVKAYVR",
    "output": "Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MELRRGGVGSQAAGRRMDGDCRDGGCGSKDAGSEDYENLPTSASVSTHMTAGAMAGILEHSIMYPVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMMMGAGPAHAMYFACYENMKRTLNDVFSHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSALSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRTLY",
    "output": "Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSAFTPASEVLLRHSDDFEQSRILFAGDMQDDLPGRFECAASRAHTQQYHHWQLLSRQMEDRVRFSLVAEQSDVADCDTLIYYWPKNKPEAQFQLMNLLSMMPVGCDIFVVGENRSGVRSAESMLAEYATLNKIDSARRCGLYHGRLDKQPTFDAEKYWGEYQLDGLTIKTLPGVFSRDGLDVGSQLLLSTFTPHTKGKVLDVGCGAGVLSAVLASHSPKVRLTLSDVSAPAVEASRATLAANGLEGDVFASNVFSEVTGRFDIIISNPPFHDGMETSLEAAQTLIRGAVRHLGSGGELRIVANAFLPYPKLLDEIFGFHEVLAQTGRFKVYRTVMTRQAKK",
    "output": "Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTPESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQINEMTLSFIPKIIAVFIAIIIAGPWMLNLLLDYVRTLFTNLPYIIG",
    "output": "Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARNKIALIGSGMIGGTLAHLAGLKELGDIVLFDIADGIPQGKGLDIAQSSPVEGFDASLTGASDYSAIEGADVCIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPNAFVICITNPLDAMVWALQKFSGLPKNKVVGMAGVLDSSRFRLFLAEEFNVSVKDITAFVLGGHGDTMVPLARYSTVAGIPLPDLIQMGWTTKEKLDQIIQRTRDGGAEIVGLLKTGSAYYAPAASAIEMAEAYLKDKKRVLPCAAHLSGQYGVKDMYVGVPTVIGAGGIERIIEIDLNKGEKEAFDKSVAAVAGLCEACINIAPSLK",
    "output": "Catalyzes the reversible oxidation of malate to oxaloacetate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPREKQKRGRRAEDKAKKDAAKRKRDEGPEESAVKRLKPSAETNTSNNEIISGADYIPLGQDDGGNDVPMNDAPANDMPFYGLLDSEEQEYFSKANEVLELNQFHDAEERRLFVDSVYREADGKELKVACSQSCSRLMEKLISLSDMRQIRRLFSKFIGHFLHLVQHRFASHCCETLFINAAPGVTEKISKSKGRKAEVDEEDEPEPELSLAEMFMKVVEELEGNWGYLLTERFASHTIRVLLFVLAGEPVDLSSTDSVVASRKKERLGIVNTEAPEEKAAAEKRKVPEVFEATLKKVMNDMVSGLDNTYLRALATHPVGNPVLQVLVFLELSHFGKASAKDPNSIIRRLIPDDDFGENAESSTFVRGLLYDPVGSRLLETIIKSMPGKLFKSLYKNIIRDRIGSLARNTTAGYVVLRTLERLGKDDLQDAMESIIPEIPGLIERSRLIVPKVLIERCLVRGVDTKPLSDALESAYDKDPAQRLEQMLKLEPAASEDDSEEKRKQTGNNQTAAAEKLHGSLLAQTMLTASGPVSGLIYSSLLAQSPDSLLRLAKDPTASRVLQQALTAPTSTSQFRRQFTTRFSGHLVELALDSSGSHVVDALWPATKDLFFVKERMAQELLNEELSLRDSFVGRAVWRNWSMDLYKRRRGEWASKAKGLDSIENGQRERPKSRIDLARAKFAAKAAEESSKAPVAAKT",
    "output": "RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMNMQSMMKQAQKLQKQMQVSQEEIANTTFVGKSAQDLVTVEFSGDRTLKSLNINPDVIDPEDPETLQDMVTDAVNDALSQIEKVTEQKLGKFTKGLPF",
    "output": "Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEKLTDLNYTLSVITLMNDTLHTIMEDPGMAYFPYIASVLTVLFTLHKASIPTMKIALRTSRCSYKVIKYCIVSIFNTLLKLAGYKEQITTKDEIEKQMDRVVKEMRRQLEMIDKLTTREIEQVELLKRIHDMLIIKPVDKIDMSQEFNQRQFKTLNEWAEGENPYEPKEVTASL",
    "output": "Plays an essential role in the virus replication cycle by acting as a viroporin. Creates a pore in the host reticulum endoplasmic and as a consequence releases Ca(2+) in the cytoplasm of infected cell. In turn, high levels of cytoplasmic calcium trigger membrane trafficking and transport of viral ER-associated proteins to viroplasms, sites of viral genome replication and immature particle assembly.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSIGTDAETKKKIIAEYAKTEGDTGSPEVQIALLSHRISHLTEHLKQHKHDHHSRRGLLLLVGQRRRLLNYLQKTEIERYRSIVERLGLRR",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKLPIYLDYSATTPVDPRVAEKMMQFLTLDGTFGNPASRSHRFGWQAEEAVDIARNQIAELVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQSNGIISLQALEAAMREDTILVSIMHVNNEIGVVQDIEAIGEMCRARGIIYHVDATQSVGKLPIDLSKLKVDLMSFSGHKIYGPKGIGALYVRRKPRIRIEAQIHGGGHERGMRSGTLPVHQIAGMGEAYRIAKEEMASEMARLRTLRDRLWNGVKDMEEVYLNGSLENGVPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGMTDELAHSSIRFSLGRFTTEEEIDYTIQLVRKSIGRLRDLSPLWDMFKQGVDINSIEWAHH",
    "output": "Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKPLASLRDIKTRINATKKTSQITKAMEMVSTSKLNRAAKREIVRSYMEKIQEVVANVASRGRSHPMLVSRPVKKTGYLVITSDRGLAGAYNSNVVRLVYPKRSKNAMLPPDEYAIIVIGRVGLSFFRKRNMPVILDITRLPDQPSFADIKEIARKTVGLFADGTFDELYMYYNHYVSAIQQEVTERKLLPLTDFLAENKQRTVYEFEPSQEEILDVLLPQYAESLIYGALLDAKASEHAARMTAMKNATDNANDVIRTLTLSYNRARQAAITQEITEIVAGRNALQ",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLTVALSKGRLLKDFIKFLERNNNHVWADAIIHRERKLQITADSIKFILVKGSDVPTYVEEGIADIGITGSDILKERPNRNINNYIDLPFGECHFSVAAKPNVTNIQRVATTYVKTTRDYFNQKGTDISIIQLSGSVELAAVVDMVDAIVDIVQTGTTLKSNGLEEREQIGEINARLITNKHSFFSKSKAIENFIQQLGVSIHAQ",
    "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV",
    "output": "Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKHWKRRSSAVFAIVLQVLVLLLPDPAVAMTMEQFLTSLDMIRSGCAPKFKLKTEDLDRLRVGDFNFPPSQDLMCYTKCVSLMAGTVNKKGEFNAPKALAQLPHLVPPEMMEMSRKSVEACRDTHKQFKESCERVYQTAKCFSENADGQFMWP",
    "output": "Odorant-binding protein required for olfactory behavior and for activity of pheromone-sensitive neurons. Binds to alcohols and mediates avoidance behavior to high concentrations of alcohols, the alcohol-binding possibly resulting in activation of receptors on T2B neurons, the activation of these receptors inhibiting these neurons. Acts in concert with Snmp and lush to capture cVA molecules on the surface of Or67d expressing olfactory dendrites and facilitate their transfer to the odorant-receptor Orco complex. Required for cVA response, probably by binding to VA. May act by serving as an adapter that bridges the presence of gaseous pheromone molecules, cVA, to activation of specific neuronal receptors expressed on T1 olfactory neurons, possibly via a specific conformational change induced by cVA that in turn activates T1 receptors. T1 neurons are excited by the pheromone VA, while T2 neurons are inhibited by alcohols. Also binds to phthalates."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPYRKYREKKYETKYREAFKVFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFLGDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVRFANELSFGGLVLLGKGEEMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIVYPKINEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSGKSKKEAEQQAAAEALKKLKEQL",
    "output": "Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MASNSAFSLFLILLIITQCLSVLNAAKDFDFFYFVQQWPGSYCDTKQSCCYPTTGKPAADFGIHGLWPNNNDGTYPSNCDPNSPYDQSQISDLISSMQQNWPTLACPSGSGSTFWSHEWEKHGTCAESVLTNQHAYFKKALDLKNQIDLLSILQGADIHPDGESYDLVNIRNAIKSAIGYTPWIQCNVDQSGNSQLYQVYICVDGSGSSLIECPIFPGGKCGTSIEFPTF",
    "output": "Probably involved in plant phosphate-starvation rescue system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "IIFSMWLLFSFSESTEYIAGDSESSWKVNFPSREALIDWATRHQFTYSDTVVNEDEDHDCNTKIHSKLGDMVVTKRPLVLPPLITLPLSPSPAPAPNTSGAAAGCGFMAFLEVSVAMLMFLIWL",
    "output": "Involved in the infection process during the plant-rhizobium interaction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "VPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGLDFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNMIQISNDLENLRDLLHVLAFSKSCHLPWASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC",
    "output": "Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, is pro-angiogenic for endothelial cell and affects innate and adaptive immunity (By similarity). In the arcuate nucleus of the hypothalamus, activates by depolarization POMC neurons inducing FOS and SOCS3 expression to release anorexigenic peptides and inhibits by hyperpolarization NPY neurons inducing SOCS3 with a consequent reduction on release of orexigenic peptides (By similarity). In addition to its known satiety inducing effect, has a modulatory role in nutrient absorption. In the intestine, reduces glucose absorption by enterocytes by activating PKC and leading to a sequential activation of p38, PI3K and ERK signaling pathways which exerts an inhibitory effect on glucose absorption (By similarity). Acts as a growth factor on certain tissues, through the activation of different signaling pathways increases expression of genes involved in cell cycle regulation such as CCND1, via JAK2-STAT3 pathway, or VEGFA, via MAPK1/3 and PI3K-AKT1 pathways (By similarity). May also play an apoptotic role via JAK2-STAT3 pathway and up-regulation of BIRC5 expression. Pro-angiogenic, has mitogenic activity on vascular endothelial cells and plays a role in matrix remodeling by regulating the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). In innate immunity, modulates the activity and function of neutrophils by increasing chemotaxis and the secretion of oxygen radicals. Increases phagocytosis by macrophages and enhances secretion of pro-inflammatory mediators. Increases cytotoxic ability of NK cells. Plays a pro-inflammatory role, in synergy with IL1B, by inducing NOS2 wich promotes the production of IL6, IL8 and Prostaglandin E2, through a signaling pathway that involves JAK2, PI3K, MAP2K1/MEK1 and MAPK14/p38 (By similarity). In adaptive immunity, promotes the switch of memory T-cells towards T helper-1 cell immune responses (By similarity). Increases CD4(+)CD25(-) T-cell proliferation and reduces autophagy during TCR (T-cell receptor) stimulation, through MTOR signaling pathway activation and BCL2 up-regulation (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTAVIALVGRPNVGKSTFFNRLTRTREALVADLPGLTRDRHYGTAQFEGRQYLVVDTGGFEPEEREGLVAAMAAQTRLAITEADAICFLVDAKEGLSTQDAEIAQELRRGGKPIYLVVNKMDAKGAVSELPEFYRLGLGTPYTISAAHGHGVEPLLEAIFSDLPTSEDDTADAARKGPRIAMLGRPNVGKSTLVNTMLGEKRVLVFDEPGTTRDSIRIPYERQGKPYVMIDTAGMRRRARVGEGLEKLSVLKTLSALREADVVLLVLDARLGIAEQDAHLVGVAVELGRPIVVVVNKWDGMTPEERKAVKQELERRLDFIRYAPVYTISALHGTGVGDLYKSIDQLWIDSRRHFSTAELNRALADVIETHQPPMVGGRRIKLRYCHQGGENPITLVFHGNQLTRLPGTYKRYLESAFRRALHLEAVPLRLVFRQGENPYDPQPKNGRQH",
    "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDDLLPEAFAVVREAATRVLGMRPYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLAQRDASEMGQLHEFLGLTVGINLNSMSREEKQEAYAADITYSTNNELGFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAFVRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVMHRDTDYVVQEGEIVIVDQFTGRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIRDDRADLIFKSMEGKFNAVVEDIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAVTIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSMEDELMRRFGSDNMKAMMDRLGMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDDVLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVALHTQEEIEEDWNIKGLVDYLNTNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDTKWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQNLERQEVVQGEAVHPSSDGEEAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK",
    "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFNTHKVEIEWGGRPLTLETGKIARQADGAVLATYGETAVLATVVSAKEPKPGQDFFPLTVNYQEKTYAAGKIPGGYFKREGRPSENETLVSRLIDRPIRPLFVDGYKNDTQVVITVLQHDLENNPDILSMVAASAALTISGVPFMGPISGARVGYIDGEYVLNPNIDEMPESKLDLVVAGTSEAVLMVESEAQELPEDVMLGAVMFGHKSFQPVIDAIIKLAEVAAKEPRDFQPEDLSELEAKVLAVVENDLREAYKITEKQARYAAVDAAKAKAKEHFFPEGVEETEMSAEQFATIFKHLQAKIVRWNILDTGNRIDGRDLSTVRPIVSEVGILPRTHGSALFTRGETQAIVVATLGTGEDEQMIDALTGTYKESFMLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIHPMLPAAEQFPYTIRAVSEITESNGSSSMATVCGTSLALMDAGVPIVRPVAGIAMGLIKEGERFAVLSDILGDEDHLGDMDFKVAGTEFGITSLQMDIKIDGITEEIMKVALEQAKGGRVHILGEMAKAISSSRAELGEFAPRIEVMNIPTDKIRDVIGSGGKVIREIVEKTGAKINIEDDGTVKIASSNGKEIEAAKKWIHSIVAEPEVGEIYEGTVVKTADFGAFVNFFGPRDGLVHISQLAADRVAKTTDVVKEGQKVWVKLMGFDERGKVRLSMKVVDQETGKEIVAEKKKEEVDAE",
    "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQEHQADQLAALSEQE",
    "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPTLRFPFHLANHNKDAAINILIIFISIGSIIFNVNYFHTTIVKNGQIINQPTNAFQSDFSLAALWRNENHAGVKDANPVAVNQETPKLSIALNGIVLTSNDETSFVLINEGSEQKRYSLNEALESAPGTFIRKINKTSVVFETHGHYEKVTLHPGLPDIIKQPDSESQNVLADYIIATPIRDGEQIYGLRLNPRKGLNAFTTSLLQPGDIALRINNLSLTHPDEVSQALSLLLTQQSAQFTIRRNGVPRLINVSVGELTGMNGLRHERTQ",
    "output": "Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIQQESQLKVADNTGAKKVKCFKVLGGSRRRYATVGDVIVCSVRDVEPNSSIKKGDVIKAVIVRTRRHITRKDGSTLKFDTNSCVIIDDKGNPKGTRIFGPVAREIRDRGFIKISSLAPEVI",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MYYPLLSIALGSVLGAWLRWFLGLKLNPIYPQIPLGTVTVNLVGGFIIGFAMAYFAHSDLSPNYKLFVITGFCGALTTFSTFSIEIVTLLQSGKWGMAMLAISIHLIGSLIFTCLGLATYYWVAGH",
    "output": "Important for reducing fluoride concentration in the cell, thus reducing its toxicity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MYRPEKISIRKVPMQREDLIQSMFAPPDAPPVRWRIAPSLVDYPEAVETMEREAAAIADGTADELVWLVEHPPLYTAGTSANAADLVMPDLLPVFATGRGGEYTYHGPGQRVVYVMLDLKRRRQDVRGFVAALESVIIATLDSMNVKGERREDRVGVWVRRPEKPPLMDGSMAEDKIAAIGIRLRKWVSFHGLSLNVDPDLEHFGGIVPCGIRGYGVTSLVDLGLPVMMADVDIRLREAFERVFGPTRTENE",
    "output": "Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSSRHRLDLDGSGRGDRRRSPNRRSRSRSRSPHRRSSPDRKRQIGAVGNMKIQINPYNNQPFSNRYWAIWEKRSQLPVWEYKEKFMELLRNNQCITLVGETGSGKTTQIPQWAVEFMKQQQQGQPPGQARLVACTQPRRVAAMSVATRVAEEMDVVLGQEVGYSIRFEDCISERTVLKYCTDGMLLREAMNSPLLDKYKVLILDEAHERTLATDILMGLIKEIVRNRADIKVVIMSATLDAGKFQRYFEDCPLLSVPGRTFPVEIFFTPNAEKDYLEAAIRTVIQIHMVEEVEGDILLFLTGQEEIEEACKRIDREIQALGADAGALSCIPLYSTLPPAAQQRIFEPAPPNRPNGAISRKCVISTNIAETSLTIDGVVFVIDPGFSKQKVYNPRIRVESLLVCPISKASAMQRAGRAGRTKPGKCFRLYTETAYGSEMQDQTYPEILRSNLGSVVLQLKKLGTEDLVHFDFMDPPAPETLMRALELLNYLQAINDDGELTELGSLMAEFPLDPQLAKMLITSTELNCSNEILSITAMLSVPQCWVRPNEMRTEADEAKARFAHIDGDHLTLLNVYHSFKQNQEDPQWCYDNFINYRTMKTADTVRTQLSRVMDKYNLRRVSTDFKSRDYYLNIRKALVAGFFMQVAHLERSGHYVTVKDNQLVNLHPSTVLDHKPEWALYNEFVLTTKNFIRTVTDVRPEWLLQIAPQYYDLDNFPDGDTKRKLTTVMQTLQRNAGRGY",
    "output": "Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRILQVSAELFPLLKTGGLADVAGALPLALMAAGQDARVLLPGFPAILAGVRELAPVAEFTAPWGPERFGLRAGRIAIDGAAAPITAYVIDAPVLYDRPGNPYEDATRQPYGDNHRRFALLGWAAAQLAQGLDPAWQPEVVHAHDWHAGLAPAYLHFAREAGLTRTGSVFTVHNLAYQGISAPWNFADLGLPAPAFHMNGLEYHGQVSFMKGGLYFADRLTTVSPTYAREIQTPEQGFGLDGLLRLRGGVLTGILNAVDDEVWNPATDSALVQGYHTPDGRHMAGKARCKAVLQHQLGLAERPDAPLFILVSRLTEQKGLHLVLGGLDTLLAEGGQLALLGSGEAGLEQAFRERAAAAPRAVSVTIGYNETLAHQLFGGGDVTLVPSLFEPCGLTQMYGLKYGSLPLVRRVGGLADTVVDCTLEDMASGHATGFVFDRFDAADYDRALRRAFALYQRAPDWRRVRGNAMRRPADWASAAGQYIEVYRQALESAGT",
    "output": "Synthesizes alpha-1,4-glucan chains using ADP-glucose."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTWFCARYAWYCQQMMQARELELEH",
    "output": "Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAIWSTRKVGLDNLRISQLLNFRGFDPSALVTKLTDPFSLQRLLTLNQSRSPPMVNRLKDSRKRRAAVVCRIRDTRDGWFSSLSSLTSSVIGLFQISVKLPHEPYKIQVMVSSQEQVQDVRQSIVELPSTFQYTCFHLEFNGKRINDFVELSEVEGLKADSEIVLVEDPYTEKEARMHVVRFRDLVGAAGDRSDNLHGLNAGLSLHDAVTAEAATDDVKEHSLSKYDIAASPSLETILPRAEAPLPKTVKSISLSAWNPPPYHLRQKGHLLYLQVTTNEGEQFQITSHVSGFYVNKCSNHKFDPLPRTTPKKVSAHSLLTLISKLSPSFNSAFEALQESNNKKDLLTTFPFQNAIPNSPWLVTPPSSNPNSHQADITRSQESYLVSGVDNAETLRDWNEEFQTTRELPRETVQDRVFRERLTSKLFADYNEAAARGAVLVARGEVAPLNPTEERDAQIFVYNNIFYSFGADGVGTFVSEGGDEAARVAVGKDVLGIKAVNQLDINGLFTPGTVVVDYLGKRIVGQSIVPGIFKQREPGEHQIDYGGVEGKDVVATHPDFVSVFEKMSKALRIKKHPVWDKEGKRHDLEGSVETKGLLGTDGRKYVLDLYRVTPLDVVWQEEPGSEDYPHRMSVLRLELVEAYWRSKMSQYVKAEVERRRAAKAQEDAANKEQPSETTESKEGESEEKAEEALDQERVDISGFQLALNPDVCSGQVPQTEEEKKQWAEDEKEVRDACEFLRSKVIPELIQDLHDGDVGFPMDGRSLSQLLHKRGINIRYLGKLAQLSKEKGSRLEALTTLLVQEMIARAFKHIANRYLRNVPAPFVASCVAHLLNCLLGADVNPKPSAEIDASLREIYPEGDFSFEKVTPETLRAEVEKQVTVRYRYTLETEWFSSLRHLQLLRDIAIKLGLQLGARDYAFTKAQLPAKVPVANGVNGASHDESKKKKKKGGDSKSPSRAVVEEKPVVSIVPDDIVNVVPLVKDASPRSSLAEEALEAGRISLMQNQKQLGQELILESLSLHEQIYGILHPEVAKLYHQLSMLYYQTDEKEAAVELARKAVIVTERTLGVDSADTILAYLNLSLFEHASGNTKTALVYIKHAMDLWKIIYGSNHPDSITTMNNAAVMLQHLKQYSDSRKWFEASLAVCESLFGKQSINTATILFQLAQALALDQDSKGAVGKMRDAYNIFLNQLGPNDRNTKEAETWLEQLTQNAVSIAKHAKDIQARRLRRINMNPRVTTLGTKVQPQVGQTAPEASGAKGAANASMDSRSIDELLKFIEGGDATSSRSKQKKRAAASNPKLRGSKKSSA",
    "output": "mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKTWLLALYDVLSRYKNVWNETWKIRKQLDSPVREKDENEFLPAHLELIETPVSNAPRFVSYSIMLFLTLAIIVSIFSNVEIIATASGKFALSGRSKEIKPIENSLVKHIFVKEGEYVKKGELLLKLTALGAEADTLKTKTSLSQAKLEEFRYKSLLEAVEKDQLPILDFSKIDLPFMTENDQKRVTLLIEEQFSTWQKQRHQKTLNLNKKEAEKLSYLARIKKYEGLINTEQVRLDDFRALYKEHAIAKHTVLDEENKYQDAINELEVYKASLMQVENEVLLAKEEQELVTQLFKNDILDKLKQATDNVNLLTFELDKNNQRQQVSEIRAPVSGTVQQLKVHTIDGVVTTAETLMVVVPEEDSLEVTALIQNKDIGFVKEGQEVVIKVEAFPYTRYGYLTGKVKNITLDAIEHPKLGLVFNTIIELDKKTLSTEEKEIPLSAGMEITAEIKTGMRSVISYLLSPLEESIDKSLRER",
    "output": "Involved in the export of the LtxA leukotoxin."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTSIVLFCRPGFEKECGAEIQEKAAWNEMYGYLELKINQGLVFFHLHESAHGEALMNKLPLKRLIFARQWFVTVTDKIDLPDYNRVEAITEALGNDWQYSDLRMEMADDNDGKSLSKFCRKLSVPLRQALRKNKVLTQKGNNSADDPEGAILHALFLSGQEVILGFSLARNSSPHVMGIPRLKFPSASPSRSTLKLDEAFLHFIPRDEWDERLTSGMNAVDLGSAPGGWTYQLVRRGMMVTAIDNGLMAESLMETGQVKHKMMDGFKYVPLKQNVYWLVCDMIEKPQRVAKLMSEWLLHGHCKEAMFNLKLPMKGRYQQVTNDLQTIKDAFTKHNVKYELYAKHLYYDREEVTVHARLLSPAPLRAKE",
    "output": "Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNTKLTVLCFLGIVTIVSCGWMSEKKVQGILDKKLPEGIIRNAAKAIVHKMAKNQFGCFANVDVKGDCKRHCKAEDKEGICHGTKCKCGVPISYL",
    "output": "[Hge-scorpine]: Has antibacterial activity against B.subtilis, but not against S.aureus. Also has hemolytic and cytolytic activities.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGDTTITNLLDSDDTRVMLDALGKLGVKLARDGDTCVVTGTRGAFTAKTADLFLGNAGTAVRPLTAALAINGGDYRVHGVPRMHERPIGDLVDGLRQIGAQIDYEQNEGFPPLRIRPATISVDAPIRVRGDVSSQFLTALLMTLPLVKAKDGRSIVEIDGELISKPYIDITIRLMARFGVNVEREGWQRFTVPAGVRYRSPGRIMVEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFAHALMQMGANVTMGDDWIEVRGIGHDHGKLEPIDMDFNLIPDAAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELRKVGATVEEGADYLVVTPPAALTPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVGKTFPDYFDRFAALAKA",
    "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAFRKSNVYLSLVNSYLIDSPQPSTINYWWNLGSLLGLCLVIQILTGIFMAMHYSSNIELAFSSVEHIMRDVQYGWLLRYMHANGASFFFICMYMHIAKGLYYGSYRSPRVTVWIVGVIIFVLTMAAAFLGYCCVYGQMSHWGATVITNLFSAIPFVGQDIVQWLWGGFSVSNPTIQRFFALHYLVPFIIAALVVMHFMALHVHGSSNPLGITGNMDRIGMHGYFIFKDLITVFVFLIFFSLFVFFSPNTLGHPDNYIPGNPLVTPASIVPEWYLLPFYAILRSIPDKLLGVITMFAAILVLLVLPITDRSVVRGNTFKVLSKFFFFLFIFNFLLLGQIGQLHIEPPFVLMGQIATFLYFAYFIIIVPIISTIENVLFYIGRVNN",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MADAEASAELPEEARPDGGTLRVLRDMASRLRIHSIRATCSTSSGHPTSCSSSAEIMSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCIDIYQRRCEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHGKPMPRERADAIIKLIESQIETSRNLDPQLPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANDRVIVLDGDTKYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDQIRIGGLSESNINIIGSHCGVSVGEDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVSLAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELLKQDIFIRVIDLFTIKPLDVTTIISSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN",
    "output": "Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDTMQGESNIVEIWTDGGCKPNPGPGGWAAILLYRGTEKELSGFDPETTNNRMELTAAAAALEALTRPCKVVLNTDSEYVRNGITRWKDGWVRRNWRNASGDPVANMDLWRRLLDAAARHEIDWRWVRGHAGNPMNERADQLATKARMEG",
    "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRIFGIILLSFCLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKLKLYINEKDISSLINLPQSSTRGNENVYYQKLNLALPNLLLERFAKNTTNLIKLEFQGCSEQGLCYNPQTWYFDLISKKDAFEISKPYKAQKTDKKTKIESEESSIANFLATDNFFWILLSFFGYGLLLSLTPCILPMIPILSSLIVAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGASIQGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLSALIVGPCVAAPLAGALIYIANTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWMEKVKIFFGFVMLAMAIWILSRIIEENYILIAYGILGVFFSVFMGIFEKSFTIISKIKKSILILILAYSLSIFLGGLFGAKNFLNPLNFNTISASKHALSYDYINNFEQLKQEIQTNTKPIMLDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSENNNEQIKTMKEFNVFGPPVLIFFENGKEKLKITGFISADDLLKKIEP",
    "output": "Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLVERRADAYQDVSIHGTLPRKKKGPPPIRSCDNFSHVGTLPHSRSPRHHSPLIQDVIQEQPLQDWKGEAFTFRDQHLLDPTLEYVKFSKERHVMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLMQRDGDFLVRDSLSSPGDFVLTCQWKNLPQHFKIRRTVVRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPVNRTVPLRCLEERYGASSPDRAHEGSLTEGRPDAAKRLSLTVGGTQAREQGLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGGKLTPQSPSVGTSPCPNSPVFRTGSEPTLSPAVVRRVSSDARPGEALRGSDSQLCPKPPPKPCKAPLLKAPPSPSIWLNSEANYCELNPALAASYDGASRLPFCAQDSYVELLTAKQNGGLGTRNSDTSYLILDDDDRTRPWKPPPAPGDTVGEDQDTFVMPLLETTSSFKPNDFESKLLPPENKPLETSMLKRAKELFTNSDPKVIAQHLLSVDCKVARILEVSEEMRKNMGVNSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGSLEDRAATLNKIIQVAVELKDSMGDLYSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGRESTCVPPNNVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEIMLNHLATARLMAEAADSYRMNAERILAGFQPDEEMSEVFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQMEF",
    "output": "Acts as an adapter protein downstream of several growth factor receptors to promote cell proliferation, migration, and redistribution of actin fibers (By similarity). Specifically involved in INS/insulin signaling pathway by mediating MAPK1/ERK2-MAPK3/ERK1 activation and DNA synthesis (By similarity). Promotes insulin-mediated membrane ruffling (By similarity). In response to vasoconstrictor peptide EDN1, involved in the activation of RAP1 downstream of PTK2B via interaction with phosphorylated BCAR1. Inhibits cell migration and invasion via regulation of TGFB-mediated matrix digestion, actin filament rearrangement, and inhibition of invadopodia activity. May inhibit TGFB-SMAD signaling, via facilitating BCAR1 and SMAD2 and/or SMAD3 interaction (By similarity). Regulates EGF-induced DNA synthesis (By similarity). Required for the maintenance of ocular lens morphology and structural integrity, potentially via regulation of focal adhesion complex signaling. Acts upstream of PTPRA to regulate the localization of BCAR1 and PTPRA to focal adhesions, via regulation of SRC-mediated phosphorylation of PTPRA. Positively regulates integrin-induced tyrosine phosphorylation of BCAR1. Acts as a guanine nucleotide exchange factor (GEF) for small GTPases RALA, RAP1A and RRAS (By similarity). However, in a contrasting study, lacks GEF activity towards RAP1 (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRLSDFDFELPEELIAQHPLAQRQASRLMVLNRVTQQLQLAQFADIADWFRPGDVLVVNDTRVIPARLIGRKQTGGRIEVFLVRRLPGVEEVWACLTKCSKSPRPGTRLILGEGLEGTVVEGGEPPYRHVRFSFQGDFSQVLEQVGRIPLPPYIRREATPDDRSRYQTVFAREAGAVAAPTAGLHFTDEILDVLRAKGVEIQPLTLHVGLGTFLPMRTDDITEHRMHEENYFVPEGTAAAVNRAKDDGRRVIALGTTSTRTLEYAVDEQGRLQAGAGTCDLFIRPGFKFRIVDGLVTNFHLPCSTLLVLVAALAGREFILEAYQRAVAEKFRFFSYGDCMLIL",
    "output": "Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEESQSKQESSTKVAQHEGQEDVDPTFKTKKLMEVELMKHRVQLERNLKLRTFPGARTKQVKEALYPLLTWSSKSKNLFQNFTKLLLFKKLCQRGSENLVRESWYPCVPEEEAHMIDIQDLFGPNLGTQKKPQLVIIEGAAGIGKSTLARLVKRAWKEGKLYRNDFHHVFFFSCRELAQYEQLSLAELIVQGQEVPTAPIRQILSHPEKLLFILDGIDEPAWVLADQNPELCLHWSQTQPVHTLLGSLLGKSILPGASFLLTTRTTALQKFIPSLEQPCQVEVLGFTLFERKNYFYKYFGKKKGGVTTFTLVKSNSALLTLCEVPWVCWLVCTCLKKQMEQGGELSLTSQTTTALCLKYLSLTIPGQHMRTQLRDLCSLAAEGVCQRRTLFSESDLCKQGLDEHAIASFLKIGVLQKQASSLSYSFAHLCLQEFFAAMSYILDDSEERHADMKNDRIVETLVERYGRQNLFEAPTVRFLFGLLSKEELKKIEKLFSCSLHGKTKLKLLWHILGKSQPHQPPCLGLLHCLYENQDMELLTHVMHDLQGTIVPGPDDLAHTVLQTNVKHLVIQTDMDLMVVTFCIKFCCHVRSLQLNRKVQQGHKFTAPGMVLYRWTPITDASWKIFFSNLKLARNLEELDLSGNPLSYYAVHSLCTTLRKRGCQLKTLWLVECGLTSTYCSLLASVLSARSSLTELDLQLNDLGDGGVKMLCEGLRNPACNLSILWLDQASLSDQVIAELRTLEAKNPKLLISSTWKPHVMVPTMNMDKEEVGDSQALLKQQRQQSGDKHMEPLGTEDEFWGPTGPVTTEVVDRERNLYRVQLPMAGSYHCPSTGLHFVVTRAVTIEIEFCAWSQYLDKTPLQQSHMVVGPLFDIKAEQGAVTAVYLPHFVALQEGIVDSSLFHVAHFQEHGMVLETPARVEQHYAVLENPSFSPMGILLRMIPAVGHFIPITSTTLIYYHLYLEDVTFHLYLVPNDCSIRKAIDDEEMKFQFVRINKPPPVDALYLGSRYIVSSSKLVEIIPKELELCYRSPGESQLFSEIDIGHMDSEIKLQIKDKRHMNLKWEALLKPGDLRPALPKIATAPKDAPSLLHFMDQHREQLVARVTSVDPLLDKLHGLVLSEDSYEVVRSETTNQDKMRKLFSLSRSWSWDCKDQFYQALKETHPHLVMDILEKLGGVSVKS",
    "output": "Acts as the sensor component of the Nlrp1a inflammasome, which mediates inflammasome activation in response to various pathogen-associated signals, leading to subsequent pyroptosis . Inflammasomes are supramolecular complexes that assemble in the cytosol in response to pathogens and other damage-associated signals and play critical roles in innate immunity and inflammation (By similarity). Acts as a recognition receptor (PRR): recognizes specific pathogens and other damage-associated signals, and mediates the formation of the inflammasome polymeric complex (By similarity). In response to pathogen-associated signals, the N-terminal part of Nlrp1a is degraded by the proteasome, releasing the cleaved C-terminal part of the protein (NACHT, LRR and PYD domains-containing protein 1a, C-terminus), which polymerizes to initiate the formation of the inflammasome complex: the inflammasome recruits pro-caspase-1 (proCASP1) and promotes caspase-1 (CASP1) activation, which subsequently cleaves and activates inflammatory cytokines IL1B and IL18 and gasdermin-D (GSDMD), leading to pyroptosis (By similarity). In the absence of GSDMD expression, the Nlrp1a inflammasome is able to recruit and activate CASP8, leading to activation of gasdermin-E (GSDME) (By similarity). Activation of Nlrp1a inflammasome is also required for HMGB1 secretion; the active cytokines and HMGB1 stimulate inflammatory responses (By similarity). When activated in the bone marrow, induces the pyroptosis of hematopoietic stem cells and progenitor cells of both myeloid and lymphoid lineages, hence allowing the removal of damaged cells, and the release of IL1B, which induces granulopoiesis .; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNTQLPSFIALYRALIATPSISANDGALDQSNERLITLLAGWLSDLGLRVEMQPVPNTRNKFNLLANYGEGAGGLMLAGHTDTVPFDEGRWTRDPFTLSEQDNRLYGLGTADMKGLFAFIIDTLRDIELHKLNKPLYILATADEETSMAGARYFAASTALRPDCCIIGEPTSLKPIRAHKGHLSEAIRITGQSGHSSDPARGVNAIEIMHNAIGHLLTLRNTLQQRYHNPAFNIPYPTMNLGHIHGGDAANRICACCELHLDMRPLPGMTLNDLNELLNQALTPIAAQWSGRLRIEHLHPPIPGYECPRHAPLVQAIEQLLGERAEAVNYCTEAPFLQEVCPTLVLGPGSIEQAHQPDEYLSTDFIVPTRTLLTQLIHHFCQR",
    "output": "Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGSLLSPEANAEVPREALSFHGNATGAQVHLDDQRSTARRRSTFHDGIVFSQRPVWPGERVALRVLRHEEGWCGGLRVGFTRLDPAQVAASCLPPFVCPDLEEQSPTWAALLPEGFVRAGNVVCFWVNRRGWLFAKVNAGRPLLLRKDVLVQGAPLWAVMDVYGTTKAIELLDPKANAWIRSGEPVPESEVISGEECVICFHNTANTRLMPCGHSHFCGSCAWHIFKDTARCPICRWQIEEVAVVSSLKAEEGS",
    "output": "E3 ubiquitin-protein ligase that plays a role in various biological processes such as lung development or innate immunity . Seems to utilize UBE2E1. Promotes innate antiviral response by catalyzing 'Lys-63'-linked ubiquitination of IRF7 ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSLIEGDSIYNLFQTQDLGIDFASSIVPDSPNKFKKNANVFNNFQQQQQQIQQQNKQSNGLIYNNNNNNNNNNNNNNNNSSSSNNNNNSSSSNNNNNSNNNNQNHNNNNNNQNHNNIQHNNAQSQVYINHNSNGSQQEEQLFSIYLQPEKENELNNSYHDNVNNNNNNNNNNNNNNNNINLNHAQQQQQQHHLPHGQPHNNNNNNQFYQIKNPMEEIYSSNGIVPNQEPNKKVEYMNEPIKQNHYNIVPESIFDVPFGVSSQTMLNVPSTNNANNNNNNNNNNNNNNKNINFKQPIQPNQLIPIPPHSNQNNNISLNNNNSNSNSNPNNNNNNSNNISTQINNLNNNINNQNNQLNGSNNGKKKEEDKSIKKRKFISSTPVKGENGGTTLIPTTDGGFNMDEERHQKRQRRLVKNREAAQLFRQRQKAYIQDLEKKVSDLTGTNSEFRARVELLNSENKLIREQLLYLRNFVTQAVSFSFPKGGSNGTNSPSGVADQFLNSILPPGLNSPLPQGILPAGMNLQNPMIMSAIAEAASKNSTFRQNIQGNLLGTPIPSPQSSLTSNSGNNSPNKPLNNNNNNNNINNNNNNNPSSPNNNLNNNNNISPNSSTSHQVPYLPQNTPPQQSTPNQR",
    "output": "Probable transcriptional regulator."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKPRHKRALMIVAALAVIGIAALLILNALNSNIALYVTPSDVVAGKAPQGQAFRIGGLVKEGSLKRDGLTVHFVITDLVKDIPVSYTGILPDLFKEGKGAVIQGNLNPQGEFIASEVLAKHDENYMPPEAKHALEQAQKNGSAK",
    "output": "Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTNIRKSHPLMKIINNSLIDLPAPSNISSWWNFGSLLGICLALQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWVLRYLHANGASMFFICLYLHIGRGLYYGSYLYMETWNVGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTNLVEWIWGGFSVDKATLTRFFAFHFLFPFIISAMVMGHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGLLVMIMSLLALVLFSPDMLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILIIIPLLHTSKQRSMTFRPLSQCMFWLLVADLLALTWIGGQPVEHPYIIIGQLASILYFLIITTLMPLAGLLENRLLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIKATYSSAKDFYSLLSGLLKVTDEIILNFTEDSIFSRYLTDDKVLMVIFKIPKEYLEDYTIDKPLGIKININDLKKILGKAKSKSATVTLEETEAGLKVTVRDEKTGTRSNIYIKGEKTSIDQLTEPKVNLSVTFTTDGDVLKDIARDLSLVGEEVEISADENTVTLSTEEAGRTYKSLLKQDKPLKSLNVESPSKAVYSIEVLKDVFKVTSISQNVTVGFGNNIPMKIEVPTDSGGQLIFWIAPRL",
    "output": "Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity). Both trimeric complexes inhibit DNA ligase and both 3'-5' and 5'-3' activity of Hel308 (Hjm) helicase, but stimulate Hjc, the Holliday junction cleavage enzyme."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MCLPSHLLSTWVLFMAAQSLGKTWLPNHCRSPIKAVCNFVCDCGDCSDETQCGFHGASTIPSTSFTCNFEQDSCGWQDISTSGYRWLRDRAGAVLHGPGPHSDHTHGTDLGWYMAVGTHSGKEPSTATLRSPVMREAAPTCELRLWYHIASRDVAELRLDLTHGVETLTLWQTSGPWGPGWQELAVNTGRIQGDFKVTFSATRNATHRGAVALDDVEFRDCGLPIPQARCPLGHHHCQNKACVEPHQLCDGEDNCGDRSDEDPLICSHHMATDFETGLGPWNQLEGWTRNHSAGSMVSPAWPHRDHSRNSAYGFFLISVAKPGTTAVLYSPEFQGSVSNNCSFTFYYYLHGSEASHFQLFLQAQGLNTPQVPVLLRSRHGELGTAWVRDRVDIQSAHPFRILLAGETGPGGVVGLDDLIMSSHCMLVPAMSTLQSSLSGPVPLALYPQTSIKLPQQTCEPGHLSCGDLCVPPEQLCDFQKHCAEGEDEHKCGTTDFESASAGGWEDISVGKLQWQWVEAQEKSKPAGDANRDAPGHFLSLQKAWGQLRSEARALTPALGPSGPHCELHMAYYFQSHPQGFLALVVVENGFRELLWQAPGGGSGSWTEEKIILGARRRPFQLEFVSLVDLDGPGQQGAGVDNVTLRDCNPMVTTESDQELSCNFERDSCSWHTGHLTDAHWHRIKSHGSQLDHTTGQGFFMFLDPTDPPARGQGALLLTRPQVPVVPKECLSFWYRLYGPQIGTLCLAMRREREEDILLWSRSGTHGNRWHQAWVTLHHQPEASTKYQLLFEGLRNGYHGTMALDDIAVRPGPCWAPKSCSFEDSDCGFSPGGWGLWTHQSNASGLASWGPWIDHTTGTAQGHYMVVDTSPNVLPKGHVAALTSEEHQPLSQPACLTFWYHMSVPNPGTLRVHVEESTRRQELSISAHGRSAWRLGSVNVQAEQAWKVVFEAVAAGVEYSYMALDDISLQDGPCPQPGSCDFETGLCGWSHLPWPSLGGYSWDWSSGATPSRYPQPSVDHTLGTEAGHFAFFETSVLGPGGQAAWLRSEPLPATTVSCLRFWYYMGFPEHFYKGELRVLLSSARGQLAVWYQGGHLRDQWLQVQIELSNSEEFQIVFEATLGGQPALGPIAIDDVQYLAGQQCKQPSPSQGEVAAPVSVPVAVGGALLFFMFLVLMGLGGWHWLQKQHCPGQRSTDAAASGFANILFNADHVTLPESITSNPQSPPDLA",
    "output": "Probably involved in the sorting and selective transport of receptors and ligands across polarized epithelia."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKVNLESFLRKLFFHYPDSDYPLSHLITKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHILATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSLATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLEIFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEIVNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNVLLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALVDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN",
    "output": "Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTTIRDVAKHAKVSVATVSRVLNKKGYVSKEAEEAVLQAIKELNYQPSSVARSLYHKTSGMIGLLIPDISNPFFPELARAVEDVASTYGYTVVLCNTDEEIEKERKYLQALKQKYVDGVILTTSFLPYKEYEQLNIPMVALDRYVNENIPLVASQNKAGARLATEHLLEQGCQFIAHIRGPKGVTPAEDRYEGFKEVVEEQEVANIVVSADFHIDEAQKVTRALLETHPTIDGIFASSDVVAAGAMKAAHMMGKRIPDDLQIVGFDGIPLGNMLVPSLTTVEQPIYDLGAVSTRLLIKQIEKKPLDTYRYEIPTKLVVRETTKGGENSENA",
    "output": "Transcriptional repressor for the ribose rbsDACBK operon."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGTVNVVNVAKKHQFSWYEKFYFWSIGKGLWITLKHFVKVAFFNKQVTIEYPDKKRQYSTRFRGMHSMKRDEQGRERCTACFCCMWICPANAIHIEAAEVTAERQHLHPEDKYAKKFEINLLRCIFCGLCEEACPKGAIYLDGTGEMAADNREDLFLTKERMMEKTGGPILGQRN",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSAEHDQIRAVAWTGAGVRLLDQRRLPQEEIYWTIACVSDVAQAITKMVVRGAPAIGIAAAYGVVLAARARFSEAGSGWKQLLEADLCDLEAARPTAINLAWALARMQAIIQGLPDHRDPESALLVEARCIHEEDIAANRRMGELGTTLIEGSVGVLTHCNTGSLATGGFGTALGVIRHAYGKGRIEKVFADETRPWLQGARLTTWELLRDGIPVVLIADSVAPYLLGQGEVQWVIVGADRIAANGDTANKIGSYGLAVAARYHNVRFMVVAPTSTIDWNLSDGTRIPIEQRPPEEVLTLGGKAIATVGAEAYNPAFDVIPAHLIDAIVTERGVVRQPTHERMKALFG",
    "output": "Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSAKLTLESIAKTFAETSIFAILFLIIVILNLGLLVFLAYQYRVYKKKQRANLTKQTYNNDYGQIVNLKQQNGAKIKELANLKDQLSELGQKFNTTLSEIINKPLVNVIDEYLDEQFKQAANFREAELNAVLDSNDQKTVFHKRLFNKFHFGVDKLANINVKNPLNLCWVDSASFTVIESDFRKLNGVGGINKKLLIEKLRIEDIIFTNIDKKYYEVQILSDSPVKVQKTVLTIRNILINDYVDNEKIESYAREANGYFNDHCKLIGKQVLERLNIFEISPKLHKFFGLLAFRYSFGQNVLSHCLETGFLTAYLALLVNFKPDVALKCGLYHDIGKADDENGKKNHTVTGAKIGDEFYFENDVKYTIANHHNKNVDNVYCRLTQIGDKLSAGRLGARSDSSVLFSQLKQELKQIVEETLAQFKTTILLGQSGRRLVIWLETNQHNNIIDNQQLTDLATTIKSKIVQNNITNRFPIKVVLRYNFEHSFDTKDKN",
    "output": "Endoribonuclease that initiates mRNA decay."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MITKDKIRVRLFSFDVKILDQSAESIVRAVQKSKAQIKGPIPLPTKIKKYTVLRSPHVNKKSREQFEMRTHKRLIDILEPTSALMDSLMKLELPAGVEVDIKQ",
    "output": "Involved in the binding of tRNA to the ribosomes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNFNVWNVKEMLSIPSGSGITKPSNWNNNQTDCSLSDSQFLFGSQFCPENSETLLPSLDAGACLRHPKQTQQNSVDSEPSIFIKYQAKPQLLGGDTKDESLFSLPLPVGKSKGLSKQFEEKKRRATDQSDSETLHSFVSHFPEVINKLQTSVEKTEENLSSRSQSILDSVETIAKTFQETARVQHDLMVESVRDKGSMEQAILEIQRTCAARQAEFMEMKSTLKNLEVLVVEQTKNLQQFCDNLSQLIVPGILEELKKFTSVPQVAGHLKDSTSQTSPSLTQSLHFTRQEKHPSEEPATWQAQEAPAGNPSTSSQRPGECGVWDEGAESGVFQKAALPTDGLHRGDGHVKNKTVPTYCKNWVMTTRSVSNHFSNLPSQRAGNGQGLMAQGASQRDVSKFEARVKNACPEYGPQSMCSFDSLEQSATEQKGRPCRKRRRGKKQQPQRSKRGGLLDRKQGQTSKAACAFIARHHCPQSPVCDPQGPLICWLTPRSSTKSTCHILGGTGETSQTARAAQGNLVQHSQRSSTDSSSQGDQQINWFSDLSLENLEPPQCKKGGTNLLCDPDFDSSDDNF",
    "output": "Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination . Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis . Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATLEDGTSEDRVANDEYKIWKKNTPFLYDLVMTHALEWPSLSVQWLPDVAKDNSDHTIHRLILGTHTSDEQNHLLISKICMPTDDAQFDASRYDTERSEYGGFGAVNGKVEPDIRINHEGEVNRARYMPQKSNIIATKSPHADVYIFDYLKHSAVPRDNTFNPLIRLKGHTKEGYGLSWNPNKEGLILSASDDQTVCHWDINANQNVAGELQAKDVFKGHESVVEDVAWHVLHDGVFGSVGDDKKLLIWDVRTSTPGHCIDAHSAEVNCLAFNPYSEFILATGSADKTVALWDLRNLRMKLHSFESHRDEIFQVQWSPHNETILASSGTDKRLHVWDLSKIGEDQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVVCSVSEDNILQVWQMADNIYNEVDEETPADVVERQQ",
    "output": "Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation . Synthetic multivulva class B (synMuvB) protein . SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIYKLAARYPIQVIAIVGILVSMAYFSFLEALTQEDFPVLIRALKRFGILDGFPNTRLPNEMILKLSSVQGEDASVWEQIPAAELGGEGFVDFDITQWYYPANAKVDVAQLVEPYRNDCIFHDASGACHFFFKEVGNWTVSSIALPSNLANPPIDYFLDSSSTVIQRILPAIREHGISWSWLLQLIARTWMNTLKIASQASKTELLIVGTAYACMLISIVSLYLKMRRLGSKFWLFFSVLLSTLFSVQFAMTLVRASGVRISLVSLIESLPFLINVVALDKAAELTRQVITRCSVSDSHSPMHEDIAKACRNAAPPILRHFSFGIVVLAIFSYCNFGIKQFFLFAAVMIYDLLLLFSFFVAILTLKLEMRRYNAKDDVRKVLIEEGLSESTARHVADGNDSSATTSAGSRYFKVRYGTKIILFIFIAFNLFELCSIPFKHYAATSAAAARLIPLVRSQYPDFKSQRLLDDGVFDDVLSAISSMSNIESPSVRLLPAVFYGAELSSTSFLSTIHSFINNWSHYISASFLSKWIVCALSLSIAVNVFLLNAARLNSIKEEPEKKVVEKVVEVVKYIPSSNSSSIDDIQKDEIAQESVVRSLEECITLYNNGQISTLNDEEVVQLTLAKKIPLYALERVLKDVTRAVVIRRTVVSRSSRTKTLESSNCPVYHYDYSRVLNACCENVIGYMPLPLGVAGPLIIDGKPFYIPMATTEGALVASTMRGCKAINAGGGAVTVLTRDQMSRGPCVAFPNLTRAGRAKIWLDSPEGQEVMKKAFNSTSRFARLQHIKTALAGTRLFIRFCTSTGDAMGMNMISKGVEHALVVMSNDAGFDDMQVISVSGNYCTDKKPAAINWIDGRGKSVIAEAIIPGDAVKSVLKTTVEDLVKLNVDKNLIGSAMAGSVGGFNAHAANIVTAVYLATGQDPAQNVESSNCITLMDNVDGNLQLSVSMPSIEVGTIGGGTVLEPQGAMLDLLGVRGAHMTSPGDNSRQLARVVAAAVMAGELSLCSALASGHLVKSHIGLNRSALNTPAMDSSAKKPATDALKSVNSRVPGR",
    "output": "Part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) . Hmg1 catalyzes the reduction of hydroxymethylglutaryl-CoA (HMG-CoA) to mevalonate . The first module starts with the action of the cytosolic acetyl-CoA acetyltransferase eg10 that catalyzes the formation of acetoacetyl-CoA. The hydroxymethylglutaryl-CoA synthases erg13 then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The rate-limiting step of the early module is the reduction to mevalonate by the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductases hcs1 (Probable)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MYDIIVAGAGHAGCEAALAAARSGSSCLLISSDLTAVARMSCNPAIGGVAKGQITREIDALGGEMAKAIDATGIQFRMLNLSKGPAMHSPRAQADRTAYTEYMKRVLEAETNLDLLQDTVTGIEVRGGQFFGVELQSGRILRAGAAILTCGTFLNGLIHIGMNHFPGGRTIAEPPVTGLTESLVAAGFTTARLKTGTPPRVDRRSIDYSIVIEQKGDENPPPFSFSSGSIAGKEQISCFLTKTTHKTHEILRTGFDRSPLFSGKVQGVGPRYCPSIEDKIHRFTERDSHHIFLEPEGFHTNEMYVNGFSTSLPEDIQIAGLQSIPGMEEVKMIRPGYAIEYDYFHPSQIRRSLETKAVENLYFAGQINGTSGYEEAAAQGLMAGINASRKLKELPPIHLQRSDAYIGVLIDDLVTKETNEPYRMFTSSAEHRLILRHDNADLRLRKFGHTAGLVDDDTYRETLSKDDEIVRMTAFLRSKTIPTTALYNLLPAESNRPMTGGQKAASALKRPGITLNRLFAALPDFAKEARLISSNPLVHEQVEINLAYEGYLKRELLQTEKVARLESLILPETFNYHSVTGLSSEGREKLLHFRPETLGQASRIMGVSPSDISVLMVRLGR",
    "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKAREIRTKIASIKNTQKITRAMELVAASKMRKAQDRMAMSRPYASKIRKVISHVAASHAEYPHPYLQQRENIKRVGYIIVTTDRGLCGGLNVNLFRTAIADMKKWQADNIGMDLCVIGRKGEAFFRRYGGNVLAVADHLGDAPEVQDIIGIVKVMLDQYDKQQIDAIYIATNEFVNTMVQKPLVRQLLPLKTDEEEVEGGYWDYIYEPDESKDLLEMLLVRYIESQVYQAVIENIACEQSARMVAMKNATENAGQLIDELRLIYNKARQAGITQEIAEIVAGAAAVE",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKTSMQRKLDQLSTRLAELNDLLSRENVTADLDQYRKLTREHAELGPVVEQYALWRQSRSDETAAQELLADPSMRDFAEDEIRSAREGMARLETELQKMLLPKDPNDDRNIFLEIRAGTGGDESALFAGDLLRMYLRFAERQRWQVEMMSESASDLGGYKEVIVRIAGQGAYSRLKFESGGHRVQRVPATETQGRIHTSACTVAVMPEADEIGEVEINPADLRIDTFRASGAGGQHINKTDSAVRVTHIPTGIVVECQDDRSQHKNKDRALKVLAARIKDKQYHEQHAKEAATRKSLIGSGDRSERIRTYNFPQGRMTDHRINLTLYRLEAIMDGDLDELIGALVTEHQAELLASLGEAD",
    "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTNVITRFAPSPTGFLHIGSARTALFNYLFARHHNGKFLLRIEDTDKERSTKEAVEAIFSGLKWLGLDWDGEVIFQSKRNNLYKEAALRLLQEGKAYYCFTSQEEIERQRQKALENKQHFIFNSEWRDKDSSTYPTDIKPVIRLKVPREGSITIHDTLQGDVVIENSHIDDMVLLRADGTATYMLAVVVDDHDMGITHIIRGDDHLTNAARQIAIYHAFGYEVPSMTHIPLIHGADGAKLSKRHGALGVEAYKDMGYLPESLCNYLLRLGWSHGDDEIISMTQAIEWFNLDSLGKSPSKLDFAKMNSLNAHYLRMLDNDSLTSKTVEILKQNYKISEKEVSYIKQAMPSLLVRSETLLDLAKLARIYLINSPIIYEQEAKEIIENCDKDLIKQVIEGLNKIEQFDKESVQNKFKEIATHNGLKLNDIMKPVRALITGMTASPSVFEIAEILGKENILKRLKII",
    "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKIKTVEFARSAFNEEQYPKDNLPQIVIVGRSNVGKSTLINTVLNRKNLAKTSSRPGKTRGINFYLINNKFYLVDLPGYGYAKVSKEMKKQWAHNIETFLNTSQNLRHGLFLIDIRRNPTEDDFLMINWFKHKNLPFTVVLTKADKVNKSESRKAVEDICKIFKINREEVIIFSALEKMGVSQVLSIFEKYA",
    "output": "Necessary for normal cell division and for the maintenance of normal septation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLRLAAAGARAIVDMSYARHFLDFQGSAIPRTMQKLVVTRLSPNFHEAVTLRRDCPVPLPGDGDLLVRNRFVGINASDINYSAGRYDPSLKPPFDIGFEGIGEVVALGLSASARYTVGQAVAYMAPGSFAEYTVVPASIAIPMPSVKPEYLTMLVSGTTAYLSLEELGELSEGKKVLVTAAAGGTGQFAVQLSKIAKCHVIGTCSSDEKAAFLKSIGCDRPINYRTEPVETVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQSPTGLSPIKAGVLPTKLLKKSASLRGFFLNHYFSKYQAAMERLLELYARGDLVCEVDLGHLAPDGRFIGLESVFQAVDYMYTGKNTGKLVVELPHPVSSKL",
    "output": "Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAPSFDTLSEQDLHEEEEEEIDFSDLKEQFEVKLEEGLDTFIVIDGLPIVPEESRQKLIKFLLRKLNAVGHTSEDAVFMPTNDKNMSEGFAFVEYETPEQAIAAVKQLHGTPLDKKHTLAVNKLMDIDRYGREGRIDEEYKPPTVEPFKEKEHLRSWLSDPNARDQFALYRNDKVGVFWNNKNNPPENVVDRAHWTQLFVQWSPKGTYLASVHPQGVQLWGGPAFSKQKQFPHPFVQLVEFSPGESYLTTWSSRPIQVEEGHPVLSFEEDGKNIIVWDIVSGKPLRSFVSHDLAGGPVEGDAAPKKKVQWPAFKWSADEKYVARMLQGQSISIYELPRMNLLGKTSVKIDGVMDFEWSPATVTRDGVKQYEQLLSFWTPEIGSNPARVALMSVPSKEIVRTRNLFNVSDVKLHWQSQGTYVCVKVDRHSKSKKSMATNLEIFRVREKGVPVEVVDSLKDTVINFAWEPNGGRFVLITTGEAPSGAAVLPKTSVSFFAPEKKGPQAGNFKLVRTIEKKTSNAIYWSPKGRFVVVATVHSQSNFDLDFWDMDFEGEKAEGEKDLAANLQLMKTVEHYGVTDIDWDPTGRYVVSSASVWTHSMENGWNIHTFAGQTLAEHPTDKFKQFVWRPRPPTLLSKEEQKQVRKNLREYSKEFDEEDKYAVDIANTAVVETRKRVLNEWVAWLRREKELMAEEKDAYGIPEDADDAKVAKDAPPVSEDQGEAVVEEIVEEIVEENEEVIG",
    "output": "RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASLFIIMDKRFAVFASSDKPNNCSRKNMFFLKNIIVLSNYLYLLYKAWIVCTTISLCCDFPLFNFLFIAIPYFTEILYNDSSLLWFLFVSLCFITLSFQSLEI",
    "output": "Has a role in meiosis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSYQGKKSIPHITSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDVYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG",
    "output": "Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton . Plays a role in axon guidance . During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone . Involved in invasive growth and cell migration . May participate in cytokinesis ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKTIELFKFMISAKSQTPDDGGLLDFIQNYLDDFEAIRVDVEGVKNLFLYKKFSQGDHLCFAGHVDVVPAGDGWDSDPYIATERDGYIYGRGAQDMKSGVAAFVQAIKDTKHFNGTLSLLLTSDEEGEGTYGTIEVLNYLRDKSMLPDFAVVAEPTCEMVFGDAIKVGRRGSINGYITLRGKQGHAAYPEKSINPINLIAPKLANMAGVDLDNGDEFFSPSKFVITDIRAGMQVTNVTPNELKMMFNVRNTTLTSQKEIREFVEKNLEDLDYDLRLTQGSYPFKTDTKTKLVKNIDASIEQISGIKPKHSTAGGTSDARHMAPLGIDVIEFGVINDTIHAINERTTKDEVKKLYEVFKHLIDTWK",
    "output": "Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRTLFLIDGEHYPPVVLDAMRRVREQLGAKGVAAAFLGGTEKIGEGADYGLPLVAAEDPVSAVRQALERYGVEAVVDLSDEPVVGYRERMRIASLALAAGARYVGSDFELRPPEMRRVPGKPSLAVIGTGKRVGKTAVTGYLARLLDREGFRPAVVSMGRGGPPEPEVLEGRRLEVGSDYLLRALERGAHAASDYYETAALSRVTTVGCRRCGGGLAGEPFVSNVLEGARIAAGLDTGITVFDGSGAAIPPVEVDRRVLVAGAHQDPEYVAGYLGAYRLLISDLLVLTMAEEPMAPPGRVEELVRRVREVRPDLPVIPAVFRPRPVGEVRGMRVAYVSTAPPAVLKRLAGHLEEGYGCEVVAVSGNLSNRSKLAEDLEGMPGVDAYLTEIKAAAVDVVTRRGAEEGRRVIYCDNDPVAEGLDGALLRLARAAGRGRSGDRGV",
    "output": "Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MATIRADEISNIIRERIEQYNREVKIVNTGTVLQVGDGIARIYGLDEVMAGELVEFEEGTIGIALNLESKNVGVVLMGDGLMIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEISSSESRLIESPAPGIISRRSVYEPLQTGLIAIDAMIPIGRGQRELIIGDRQTGKTAVATDTILNQQGNNVICVYVAIGQKASSVAQVVNALQERGAMEYTIVVAEAADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDPSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSRLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFSSDLDKATQNQLARGQRLRELLKQSQAKPLTVAEQILTIYTGTNGYLDSFEIAQVRKFLDELRDYVKTRKPQFEEIISSTKIFTEEAQALLKDAIQEQKELFLVQE",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKKLSKNQQKVRALFDANQAYDLHEAIELAKKTSYTKFDASVDLAFKLNLDVRKADQQLRGSVLLPKGTGKDVKVLVVTNNPEKQKLATEAKADFVLDAAAFEQKLKEDDYNFDVIVADPAMMPILGKYGKKLGPKGLMPNPKTGTVTPTPEKAVEELKKGKANYRTDKAGVVHSLIGKVSMPTESLVENAQTLISLIKKLKPAAVKGTYMQNLTVSSSMGPGIKIKLEK",
    "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNELLKSCVNGRTLNEIEAHSIMRDMMTGSLSAAEIGGLLSVLAYRGETAEEITGFVRAMREQAHTIDGPEHVVDTCGTGGDGSSTFNISTAAAIIASSAGAKIAKHGNRSVSSKSGSADVLEYLGVSIQTSPEETIKSIERRNMGFLYAPSYHSSMKHVAGARKDLAFRTVFNLLGPLSNPMKAKRQVIGVYSIEKAKLMARALEAFEPEHVLFVSSRDGLDELSITSPTDVIELKGGKTYEYTVEPGDVGLPLGRLRDIQVATPEESGRLIVDILKNRGPDSAVHIAAFNAGAALYVAEQAADLKEGVALALEAVAGGEALNQLERLKQKEEELYA",
    "output": "Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKATTMSHLRQWKLEKRKFATLTAYDASFAQLFAEQGIEVLLVGDSLGMTLQGFDSTLPVTTADVAYHTRAVRRGAPHCLLLADMPFMSYATPEQTFANAAELMRAGANMVKLEGGSWLCDTVRMLAERAVPVCGHLGLTPQSVNIFGGYKVQGREEVAANQLLKDAQALENAGAQLLVLECVPVELAQRVTEALAIPVIGIGAGNVTDGQILVMHDALGITGGHTPKFSKNFLAQSAGDIRAAIKLYIQEVESGAYPAEEHTFQ",
    "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDKYTNRDHPDYIPGTFNIYSSQNLENGIIYESKLKKTSSGVVLIPQPSYSPNDPLNWSSWRKLAHFGLMAFITAFTAATSNDAGAAQDSLNEIYGISYDSMNTGAGVLFLGIGWSTLFLAPFANLYGRKITYIVCTTLGLFGALWFALAKRTSDTIWSQLFVGISESCAEAQVQLSLSDIFFQHQLGSVLTVYIMCTSIGTFLGPLIAGYISAFTNFRWVGWVAVIISGGLLITIIFGCEETYFDRGQYMTPLTSCQSGYEDGTTLQNSDNTAVSRRKRHLDAKLSTPGAMGEKGVDLSETAEFEVNNEEEVTIPETRELIDGSKEHLKPYPKRVAILTKATNLKGYGFKQYFKYLKINLRMFLFPPVWLSGMFWGIQDVFLTFYLTTQESAYYEPPWNYSDFGVAIMNVPTLIGAVIGCICAGIVSDYFVLWMARHNRGILEAEFRLYFSIATAIIGPAGLLMFGIGTARQWPWQAIYVGLGFVGFAWGCSGDIAMAYLMDCYPDMVLEGMVCTAIINNTISCIFTFTCSDWLAASGTENTYIALAVINFGITAFALPMYYYGKRIRLWTKRWYLQSVNLRDGV",
    "output": "Seems to be involved in the uptake of several cations and of histidinol."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MHNLIKDLKARNLINNITNEEKLKKALAENKGIYVGFDPSADSLHLGNYIMIMLLKRFRLHNIKTFALVGGATGMIGDPSGKSAERNLLDKTILEHNITKIKYQLEKFTNSQVINNYDFYKNMTFLDFLRDVGKLININYLLEKEIISSRLDVGISYTEFSYNLLQGYDFLQLYKNDNIAIQAGGSDQWGNITTGIEIIRKSLGDDNIACGLTINLLTNSEGKKFGKSEKGAIYLDENKSSVYEMYQFLINQTDADVEKLLNFLTLIDVDEINKIMQAHKENPALRIAQKALAQAVVVDVHGQQKYEQALHISQVLFNGNINELNQEEFNIAIKSLPTTKLDKDEIKIIDLLNLANISSSNRVARDFLSTGSILVNDIKVNDENFLVKKQDAINQEFSIIKKGKRNYFLIVWNKD",
    "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDPNTVSSFQVDCFLWHVRKQVADQELGDAPFLDRLRRDQKSLRGRGSTLGLNIETATRVGKQIVERILKEESDEALKMTMASAPASRYLTDMTIEEMSRDWFMLMPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTNEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWRSSNENGRPPLTPKQKRKMARTIRSEVRRNKMAD",
    "output": "Prevents the establishment of the cellular antiviral state by inhibiting TRIM25-mediated RIGI ubiquitination, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors IRF3 and IRF7. Prevents human EIF2AK2/PKR activation, either by binding double-strand RNA, or by interacting directly with EIF2AK2/PKR. This function may be important at the very beginning of the infection, when NS1 is mainly present in the cytoplasm. Also binds poly(A) and U6 snRNA.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MATSISARLIYYAKLSKPRIIWLLDLAALSGAFLSGKLMPLSILAVLVGGTFASAGSMIINEGIEIDKDKVMKRTSKRPTVMGYVSQKEAIYVGIALLTLGTLVGLLDNPLTSFFILLGGLVYVLVYTVWLKPRSPLNIVIGGLAGSAAAWAGYASTTSSFTIPSILLGLLIFMWTPGHFWALALKFKEDYSRAGIPMLPVIMPENFSAKMIALSNALMIPFALALYLYAGVIYGIVAGILSAVQMYFSVRLMRNPTGEEAWRSFKFSSPYLAILLILIILTRLI",
    "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVEALLSGIVLGLIPITLAGLFVTAYLQYRRGDQLDL",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTTPYPRSDERRRMVDLQIAGRGIRDPRVLAAMAEVPRHLFIPPPYDRDAYADTPLPIGNDQTISQPYIVALMTELLHPCPEDRVLEIGAGSGYQAAILARLAAKVVTIERLGAVAAQARANLAAVGAENVEVIEGDGTFGYPLSAPYDGILVTAASPEIPQPLTEQLADKGRLVVPVGGRAMQDIVVLERDGSRYREERIEGVRFVPLIGKYGWEN",
    "output": "Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQEENERKGTARFGHEGRTWGDAGAAGGGGTPSKGVNFAEEPRHSDSENGEEEEEEAADAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA",
    "output": "Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSEKQVFSTEWAGKTLSVEVGQLAKQASGAALIRYGDTVVLTAAVGSKKPRPGDFFPLTVNYEEKMYSVGKVPGGFLKREGRPSDRATLTARLIDRPIRPLFAEGFRNEVQITSTVFSVDQDCSPEMAAMLGSSVALVISDIPFEGPIAGVDVGRIDGKYVINPTIEQAEKSDISLTVAGTYDAINMVEAGAKEVSEEAMLEAIMFGHEEIKRLCEFQQQIIAAVGKEKREIELFVSDPELEAEVKAASEGKMKAAIKTEEKKAREAAIEDVKEEILESYKAKELENEAEILSEVAHILEMIEKDEMRRLISQDKIRPDGRKVNEIRPLSSEVGMLPRVHGSGLFTRGQTQALSVCTLAPLREHQIIDGLGTEEYKRFMHHYNFPQFSVGETGPRRAPGRREIGHGALGERALQYVIPSEEEFPYTIRLVSEVLESNGSSSQASICGSTLAMLDAGVPIKAPVAGIAMGLVKLGDDYTILSDIQGMEDHFGDMDFKVAGTKDGITALQMDIKIDGLSRQILDEALTQAKEGRLHILEHLTSTISAPREELSAYAPKIITLNIKPEKIKDVIGPGGKQINAIIDETGVKIDIEQDGTVYIASQDQAMNRKAIAIIEDIVREVEVGEVYTGKVRRIEKFGAFVELFKGTDGLVHISELAHERVGKVEDILKLGDEVTVKVIEVDQQGRVNLSRKALLEKKEQPEGDKKPQAEKKFYPKTKKPESK",
    "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDELAGGGGGGQGMAAPPRPQQGPGGNLSLPPGANGAPGGGGPPAAEAAGPPAGPELSRPQQYTIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDVEAPPAPQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVEAKNLEQILNGGESPKQKGQEIKRPPGDVLETFNFLENADDSDEEENDMIEGIPEGKDKLRIHKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEARSSGDGTEWDKDDLSPTAEVWDVDQGLISKLKEQYKKERKGKKGVKRVNRTNLCDMITDLGDDELPHIPSGIINQSRSASTRMADHEGARAEEAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNPKYTLRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV",
    "output": "Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPLGLGRRKKAPPLVENEEAEPSRSGLGVGEPGPLGGSGAGESQMGLPPPPASLRPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPAAEVMFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIQLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSSGGHPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY",
    "output": "May be involved in G protein-linked signaling."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNRSQILTDRQQQELNKAILQYLEPMLTESSSDQEVYRSLQQILVPPSSSSSEAIVDNYLEKKWSTVLRLQRKIIDLENEVGTLRSIVDGQQSVSNGAASVISKDRINWLPNRASKSFPTQQNQLVMASVIHPVLPVIFGGCSDGSIIVWNIVNDDTSIPEKIIRAHTRSINKLAFSVEPADLSKDLTKSKTYIFASCSADLSIKIWDSSSYRHIRTLTGHDHTVSSVAFSQSNPDHLYSVSRDKTVKIWDLVNGYCVKSFTGHSEWVRDIDVASVNSQLSLNNMKVSAELGDFVVTCSNDQSVRVSHAESGAGLALLIGHTHVIEKVKFLPAVSNTILDKFLKENHAQFPSIPQELVSDEIFTTTLGYKYCISGGRDNLLKLWLIPPPTLIPHRSPLPAQHNNSQGWAIADLVGHQSWVKAIAIHPNGRFIFSGSDDKTIKVWDLANLNVTGSVKCVRTLSGHDGFINDLDFAAFNRDSGKEDKIKEDATEEESHQQLMKFIEGRMRCLFISGAADNSIKLWS",
    "output": "Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "METLDYRFDGTTHAHFPTNAVLVGVLASGNLEILLEPAALDGAMTVRIITAAQGFGSVWQAVITDFARRHPLRDVRISINDAGATPAVVSLRLDQAVETLLGGGTP",
    "output": "Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKTKEVVDDITMNRAITRITYEIIERNKELNQVVLAGIKTRGVHLAHRIQKRLAQLEQIDIPVAEIDTKPFRDDKKSQEADSTLIPVDITDRQVILIDDVLYTGRTIRAAIDNLVSHGRPSRVSLAVLVDRGHRELPIRTDYIGKNIPTSRTEEIIVEMTETDGQDRILIKGE",
    "output": "Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATTYEEFAAKLDRLDAEFAKKMEEQNKRFFADKPDEATLSPEMKEHYEKFEKMIQEHTDKFNKKMREHSEHFKAKFAELLEQQKNAQFPGK",
    "output": "May be involved in the regulation of the cytoskeleton through interaction with the subpellicular microtubules. May be involved in parasite mobility and attachment to the surface of the host cell. Behaves as a strong immunogen during infection (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDLIETINAVVELQHRVRNLSPNTNIYQDGQTTINDYNAIASRCNGKVYNLRDQIAQLSPFQVHMPVIPISTILSTDDHETMSAGIESLFDVLAAAIRTEGSRQNRAVVTKSIEPEVLKAVLDIGIRSQFSENPYANMLQVDTAKMEQQLEPIDDPLASQRINMLAAGGATNNTGGGYHALVGRATGKTGIITIIQGRPGAVTFNLNMKVPCSGVLSLTLLPAPGVIQLSLGNQPPNNIPVHAECVDVSTVFTEGDIVIRFELAGRVVGNANKLGTLNFPLCDRISITIEPWNANKQNNANANFNNWPAGTAQRQPTISLFVNIINASSLIDYETHSKYLAGATYLMGTTFSEDSFIASPPNVVWTMSSLLSGAPPQYIHWTRKIACMIAAFSCKI",
    "output": "Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAEVPELASEMMAYYSGNEDDLFFEVDGPKQMKCSFQDLDLCPLDGGIQLQISHEHYNKGFRQAVSVVVAMEKLRKMLVPCPQIFQDNDLSTLIPFIFEEEPVFLDTRNNDACVHDAPVRSLHCTLRDAQLKSLVMSGPYELKALHLQGQDLEQQVVFFMSFVQGEESNDKIPVALGLKAKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTRGGQDITDFTMQFVSS",
    "output": "Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKLIVPQWPQPKGVAACSSTRIGGVSLPPYDSLNLGAHCGDNPDHVEENRKRLFAAGNLPSKPVWLEQVHGKDVLKLTGEPYASKRADASYSNTPGTVCAVMTADCLPVLFCNRAGTEVAAAHAGWRGLCAGVLEETVSCFADNPENILAWLGPAIGPRAFEVGGEVREAFMAVDAKASAAFIQHGDKYLADIYQLARQRLANVGVEQIFGGDRCTYTENETFFSYRRDKTTGRMASFIWLI",
    "output": "Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine . Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate . Also has adenosine deaminase activity . May also act as a polyphenol oxidase: able to oxidize syringaldazine and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) in vitro ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRVELARFIENPGDPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVMLACVVVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVASWFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT",
    "output": "Rhomboid-type serine protease that catalyzes intramembrane proteolysis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MENTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIYMRGRIVIGEGERDDAPMLYIGEEVGICTQPNADQLCNPDELVEIDIAVDPCEGTNLVAYGQPGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGKVDINKSATENLKILSECLDRSIDELVVVVMKRDRHQGLIKEIRDAGARVQLISDGDVGAAISCGFAGTNVHALMGIGAAPEGVISAAAMRALGGHFQGQLIYDPEVVKTGLIGESKQANLDRLSSMGINDPDKVYDAHELASGENVLFAGCGITSGNLMQGVRFFHGGARTQSLVISSQSQTARFVDTIHMAGQPKTVQLH",
    "output": "Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEEKYIMAIDQGTTSSRAIIFNKKGEKIASSQKEFPQIFPQAGWVEHNANQIWNSVQSVIAGAFIESSIKPGQIEAIGITNQRETTVIWDKKTGLPIYNAIVWQSRQTAPIADQLKEDGYTDLIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGELLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDEEILKLLNIPKAILPEVKSNSEVYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNTGEDMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMIETSPESEALALASTSDDEIYVVPAFTGLGAPYWNSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDVIDTMQIDSGIDIQQLRVDGGAAMNNLLMQFQADILGIDIARAKNLETTALGAAFLAGLAVGYWEDLDSLKELNETGQLFKASMNESRKEKLYKGWKKAVMATQIFAEE",
    "output": "Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSNESIKAEQDLIQEGVESEVSTAEASLIDELTQANFRIEELEQLLAEALAKVEEQKDSVIRAAAEVDNIRRRAAMDVEKANKFALEKFANELLPVLDNMERALMGTNPEDEATKSIYQGVELTQKSLLTAVAKFGVKQIDPQGQSFNPDQHQAIGMQPSAEFPANTVMLVMQKGYELNSRLLRPAMVMVSQGGPNQESATIDIEA",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKIKIYIYILLACYIASFLRLFINNNFIVSIIGSLLFGFFIDKRLSYSIEKIILSGFFSCFTSFSGFIYFLYKVFNQGDLMKFIIFCNLIIIINLLVMYFGFWISRKIT",
    "output": "Important for reducing fluoride concentration in the cell, thus reducing its toxicity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTIDNPSAFLKTLPTGSGVYQIQDAQGKVIYVGKARNLQKRVSSYFRRQLDSKTQAMMAQVQSIQTTITRNENEALLLEASFIKQFRPRYNVLLRDDKSYPYLYLATHQKFPRLDFYRGAKKAPGRYFGPYPNAGSVRENLALIQKLFKLRQCSESFFKNRTRPCLQYQIKRCTAPCVGYVNEQEYRRQVEDAILFFEGKNDQVIIKLTERMEVASENLVFEEAAHYRDQIRQLRRLQKQQIITGGKGNIDIIGIAESNGAIGFAILFIRSGRMIGHKPFFPNTPLGTTLQTALVEFIPQYYLSPLRNGDIPERIVTSEPLEDRLWIQRALSSGLNRRLAITDQKRAPYKQWQAMAALNAAQALSQHLAQKNTFALKLEAIQKSLALPNPIARIECFDISHTLGEATVASCVVFGEEGLIKKDYRRFNISGVTPGDDYGALRQALTRRYVRLKEGEGILPDVLLIDGGMGQLRQAAEVLEELQVSGVILTAIAKGPGRKAGLEKLFVWGRREEIHLPADNIAFHLIQQIRDEAHRFAITAHCNRRAKRRVESTLQEIEGIGPKRRQKLLKYFGGLQELQRASIEEIARVPGVSETLAKAIYDACHQHKG",
    "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASPISGFDSGFSTFAQGFVALGSFRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGVFYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYARKK",
    "output": "Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Probably responsible for the translocation of the substrate across the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKIGIIMGGISTEREVSLNSGREVIKYLELLEHEIIPIIIDKKEDVMEKAKGIDFAFLALHGEFGEDGTVQSVLQTLDIPYSGCGPLTSAICMDKDMTKKILKYANINTADWVNVSSVENIDYEAIEKIGYPVFVKPNSGGSSVATNLVKDKEGIKEAVELALKYDKEVMIENYTKGEEITCCMLNGKMLPVLAIRPHAEFFDYTAKYADGGSDEVVIELEENLHKKVEEMALACWKELKCEVYVRVDMIVKDGIPYVLELNTLPGMTKNSLFPKSANAVGISFAELLNSIVKYSLEVER",
    "output": "Cell wall formation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDRYAVRTWGIVGILGCAAVGAAPTGPASDTTNATARLPTHPPLIRSGGFAVPLIVGGLCLMILGMACLLEVLRRLGRELARCCPHAGQFAP",
    "output": "Functions as an activator of viral protein expression and virus production. In turn, promotes cell-to-cell spread as well as syncytia formation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAQPQNVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATLGVEVHPLHFHTNFGEICFNVWDTAGQEKLGGLRDGYYIQGQCGIIMFDVTSRITYKNVPHWWRDLVRVCENIPIVLCGNKVDVKERKVKAKAITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGNPNLEFVASPALAPPEVQVDQQLLAQYQQEMNEAAAMPLPDEDDADL",
    "output": "GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MASTFSGDETAPFFGFLGAAAALVFSCMGAAYGTAKSGVGVASMGVMRPELVMKSIVPVVMAGVLGIYGLIIAVIISTGINPKAKSYYLFDGYAHLSSGLACGLAGLSAGMAIGIVGDAGVRANAQQPKLFVGMILILIFAEALALYGLIVGIILSSRAGQSRAE",
    "output": "Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSSRDFSNDLFSINIEENAGCVVSAKVQANPLVTQKCHKEALKTVKKNVVLPGFRKGKAPDNIVESRYSTQVEQELRRLFLRASFEALSQMCDRKPLSPKAVRSSAIDTCNPVNGGSVSFLYEAFPVIPSLPWEQLSLPDPEPVKEISEEDLENGLKNVAYFFATKTPVTRPSQEGDFISLSLYVSKRGDENSTPVAIFENKYFKISEEDMTDSFKARFLNVSTGHRVEEEIGSEDIQSFLNGDLLTFTVNAVIEISSPEMDDEKARQLQAESLEDLKKKLRIQLENQAKEAQHQKRFSDAEDALAQLIDFDLPESLLQEREELLSREKLLNARLVKYCSDSELEEQKQALLEEAKADARKAVKLLFLTQKVFSEKGLSISREELQYMMDVCSRERFGGYPPKDISNEMIQELVLVARDRLTYRKAIEAISSEKKDLEVVPS",
    "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLPVHTEVKPNPLQDANLCSRVFFWWLNPLFKTGHKRRLEEDDMFSVLPEDRSKHLGEELQRYWDKELLRAKKDSRKPSLTKAIIKCYWKSYLILGIFTLIEEGTRVVQPLFLGKIIEYFEKYDPDDSVALHTAYGYAAVLSMCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTVLLWVEIGISCLAGLAVLVILLPLQSCIGKLFSSLRSKTAAFTDARIRTMNEVITGMRIIKMYAWEKSFADLIANLRKKEISKILGSSYLRGMNMASFFIANKVILFVTFTSYVLLGNEITASHVFVAMTLYGAVRLTVTLFFPSAIERGSEAIVSIRRIKNFLLLDELPQRKAHVPSDGKAIVHVQDFTAFWDKALDSPTLQGLSFIARPGELLAVVGPVGAGKSSLLSAVLGELPPASGLVSVHGRIAYVSQQPWVFSGTVRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVGKHLFQLCICQALHEKITILVTHQLQYLKAASHILILKDGEMVQKGTYTEFLKSGVDFGSLLKKENEEAEPSTAPGTPTLRKRTFSEASIWSQQSSRPSLKDGAPEGQDAENTQAVQPEESRSEGRIGFKAYKNYFSAGASWFFIIFLVLLNMVGQVFYVLQDWWLSHWANKQGALNNTRNANGNITETLDLSWYLGIYAGLTAVTVLFGIARSLLVFYILVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTFLDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSVVFLVLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIFVIVVAFGSLVLAKTLNAGQVGLALSYALTLMGMFQWSVRQSAEVENMMISVERVIEYTDLEKEAPWECKKRPPPGWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWRALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKNNRILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNPESLFYKMVQQLGKGEAAALTETAKQVYFRRNYPDITFTSPAVMNTSNGQPSALTIFETAL",
    "output": "ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells. Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates also the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4). The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH). Transports a wide range of drugs and their metabolites, including anticancer, antiviral and antibiotics molecules (Probable). Confers resistance to anticancer agents (Probable)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNKVEAGNELGFRVGFSGHGGHLRVEPFYTAERDDALNSLPDFVSPPAFAKETKESIKKHIEEKYLIPRLEPDQFSAEKAENQWDFDWFSRVKMPLQPSLPRSVVVPTWELPFRRQKEDTENGAWEPKSVEVDLSEQMYGDQDSGFFPRMVGPPKDFLRGSVNNRPFRPGGLEDSQSSERVLPEGVSSGQWVQELLNGGPAQTVPPSFKQSLDLGDLMPYPQTWSVYEDHSSHGNASDENSSKLSIQFDDLFKKAWEEDTFSELEGDDHTAGSESPKAEAEPDAKASISNEVSKGLETDVTVLDEILSSAKTAIMSEEAVTGSSDKQLRKEGWATKGDSQDIADRFYELVPDMAIEFPFELDNFQKEAICCLEKGESVFVAAHTSAGKTVVAEYAFALATKHCTRAVYTAPIKTISNQKYRDFCGKFDVGLLTGDVSIRPEASCLIMTTEILRSMLYRGADIIRDIEWVIFDEVHYVNDVERGVVWEEVIIMLPRHINFVLLSATVPNTFEFADWIGRTKQKEIRVTGTTKRPVPLEHCLFYSGELYKVCENEVFLSKGIKDAKDSQKKKNSNAVSVAPKQQMGSSAHQDGSKSQKHEAHSRGKQNKHSSVKDVGKSSYSGNSQNNGAFRRSAASNWLLLINKLSKMSLLPVVVFCFSKNYCDRCADALTGTDLTSSSEKSEIRVFCDKAFSRLKGSDRNLPQVLRLQSLLHRGIGVHHAGLLPIVKEVVEMLFCRGVIKVLFSTETFAMGVNAPARTVVFDALRKFDGKEFRQLLPGEYTQMAGRAGRRGLDKTGTVVVMCRDEVPDESDLRRVIVGSATRLESQFRLTYIMILHLLRVEELKVEDMLKRSFAEFHAQKKLPEKQQLLMIKRSLPTKHIECIKGEPAIEDYYDMYMEANEYNNKMSEAVMQSPYAQSFLVQGRVVVMKSGMGIDNLLGIVLKGPSNTNRQYVVLVIKSEIPPPEKNMVSIGKKSSDPSQGYFIAPKSKRGFEEEFYTKPSSRKGPVVIKIELPYHGVAAGVGYEVKGFDNKEFLCICDSKIKIDQVRLLEDGNKAAFSQTVQQLLDLKSDGNKFPPALDPVKDLKLKDAELVETYYKWTNLLQKMSMNKCHGCVKLEEHMKLAREIKKHKTDLKDLEFQMSDEALLQMPAFQGRIDVLKNIGCIDDDLVVQIKGRVACEMNSGEELICTVCLFENQFEELEPEEAVAIMSAFVFQQKNTSAPTLTPKLAKAKQRLYDTAIRLGELQAQYNLQIDPEEYAQENLKFGLVEVVYEWAKGTPFAEICELTDVPEGLIVRTIVRLDETCREFKNAAAIMGNSALHKKMDAASNAIKRDIVFAASLYVTGV",
    "output": "Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C) . Involved in the regulation of potassium deprivation stress response ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAASISGYTFSAVCFHSANSNADHEGFLLGEVRQEETFSISDSQISNTEFLQVIEIHNHQPCSKLFSFYDYASKVNEESLDRILKDRRKKVIGWYRFRRNTQQQMSYREQVLHKQLTRILGVPDLVFLLFSFISTANNSTHALEYVLFRPNRRYNQRISLAIPNLGNTSQQEYKVSSVPNTSQSYAKVIKEHGTDFFDKDGVMKDIRAIYQVYNALQEKVQAVCADVEKSERVVESCQAEVNKLRRQITQRKNEKEQERRLQQAVLSRQMPSESLDPAFSPRMPSSGFAAEGRSTLGDAEASDPPPPYSDFHPNNQESTLSHSRMERSVFMPRPQAVGSSNYASTSAGLKYPGSGADLPPPQRAAGDSGEDSDDSDYENLIDPTEPSNSEYSHSKDSRPMAHPDEDPRNTQTSQI",
    "output": "Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked polyubiquitin, leaving the last ubiquitin chain attached to its substrates . May act as a central scaffold protein that assembles the various components of the BRISC complex and retains them in the cytoplasm . Plays a role in regulating the onset of apoptosis via its role in modulating 'Lys-63'-linked ubiquitination of target proteins (By similarity). Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1 . Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activities by enhancing its stability and cell surface expression . Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination . Required for normal induction of p53/TP53 in response to DNA damage . Independent of the BRISC complex, promotes interaction between USP7 and p53/TP53, and thereby promotes deubiquitination of p53/TP53, preventing its degradation and resulting in increased p53/TP53-mediated transcription regulation and p53/TP53-dependent apoptosis in response to DNA damage ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNDLIINHIAELILPRSTDKPLKGKELDELNVVKNGTVVIKDGKIVYAGQHTDDYDATETIDASGKVVSPALVDAHTHLTFGGSREHEMSLKRQGKSYLEILEMGGGILSTVNATRETSEDDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLKVSNRLAEKHDLDMKHTFLGPHAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETGVFTIEQSQHYMQKAKEAGFKVKIHADEIDPLGGLELAIDEQAISADHLVASSDKGKEKLRNSDTVAVLLPATTFYLGKEDYADARGMLDNNGAIALATDYNPGSSVTNNLQLVMAIAALKLKLSPNEVWNAVTVNAAKAIDINAGTINTGDKANLVIWDAPNHEYIPYHFGINHAEKVIKDGKVIVDNTLSFKA",
    "output": "Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKKLHVVSLGCTKNLVDTEVMLARLPEYEITQIPEEADLIIVNTCGFIGPAKEESLQTVFDLHSRRKKDSTLVMAGCLSERYKEELQKEMPEVDIFTGVGDYAKIDELISQKKSSFSDQVYLIRSEERIITGSNYHAYIKLSEGCNQQCSFCAIPSFKGKLQSRPIEDIVQEIKNLVAKGYKDFTFVSQDSSSYLRDFGIQESLVDLIHAVEEIEGIMSARILYLYPSTTTPKMIDAIANSPVFVNYFEMPIQHISDSLLKKMKRGIGAQKTKELLYAMRAVPESFLRTSLIVGHPGESEEDFHELVEFLEDFEFDRINLFAYSDEEGTKAYEMEEKIPQEVIEERLAILDAIVKKQQMKSLEKDLGKTVECYLDGTSEESELLLSGRKKIWAPEVDGEILINDSEIDNLQIGNLYKVHINERLGDKLVGTVRA",
    "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDSRPQKIWMAPSLTESDMDYHKILTAGLSVQQGIVRQRVIPVYQVNNLEEICQLIIQAFEAGVDFQESADSFLLMLCLHHAYQGDYKLFLESGAVKYLEGHGFRFEVKKRDGVKRLEELLPAVSSGKNIKRTLAAMPEEETTEANAGQFLSFASLFLPKLVVGEKACLEKVQRQIQVHAEQGLIQYPTAWQSVGHMMVIFRLMRTNFLIKFLLIHQGMHMVAGHDANDAVISNSVAQARFSGLLIVKTVLDHILQKTERGVRLHPLARTAKVKNEVNSFKAALSSLAKHGEYAPFARLLNLSGVNNLEHGLFPQLSAIALGVATAHGSTLAGVNVGEQYQQLREAATEAEKQLQQYAESRELDHLGLDDQEKKILMNFHQKKNEISFQQTNAMVTLRKERLAKLTEAITAASLPKTSGHYDDDDDIPFPGPINDDDNPGHQDDDPTDSQDTTIPDVVVDPDDGSYGEYQSYSENGMNAPDDLVLFDLDEDDEDTKPVPNRSTKGGQQKNSQKGQHIEGRQTQSRPIQNVPGPHRTIHHASAPLTDNDRRNEPSGSTSPRMLTPINEEADPLDDADDETSSLPPLESDDEEQDRDGTSNRTPTVAPPAPVYRDHSEKKELPQDEQQDQDHTQEARNQDSDNTQSEHSFEEMYRHILRSQGPFDAVLYYHMMKDEPVVFSTSDGKEYTYPDSLEEEYPPWLTEKEAMNEENRFVTLDGQQFYWPVMNHKNKFMAILQHHQ",
    "output": "Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response . VP35 binds to and stabilizes monomeric NP, keeping it soluble . Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released . The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. The nucleocapsid is helical with a pitch of 10.81 NP per turn and a diameter of about 22nm . Each NP binds to six nucleotides of viral genomic RNA, three being exposed to the solvant and three hidden into the nucleocapsid . Recruits also host PPP2R5C phosphatase to dephosphorylate VP30 and thereby promote viral transcription . Upon virion assembly and budding, NP binds to VP24 and possibly host STAU1 ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MENKLSFEEAISQLEHLVSKLEQGDVPLEEAISYFKEGMELSKLCDEKLKDVQEQMAVILGEDGELKPFTALGDEA",
    "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRTLCSLLLICCLLFSYTTPAVGDLKHLILKAQLTRCYKFGGFCHYNICPGNSRFMSNCHPENLRCCKNIKQF",
    "output": "Has antibacterial activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDLRVIENLETELAIEIEGEDHTFMNVLKGALLELDGVTAATYDVNPEQSGGQTEPIVTIKTDGSIDPLDALEQGASRVRDKTDAFEEAFEAAA",
    "output": "DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAADEELSGVWQARVVTLFPDAFPGVLGLSLTGKALQDGRWQLHTHDLRSFGVGKHRNVDDTPAGGGAGMVMRADVVGPAIEAAQRFARGRWPILYMSPRGRPFTQKMAKDLARCDGVTVLCGRFEGVDERVLEHFGVTEVSIGDYVLTGGEIAAQTVLDATVRLLPGVLGNAESTVEESHSNGLLEHPQYTRPAIWEGHAIPEVLMSGNHAEIAKWRAAQSHRLTQSRRPDLWAAKGAKE",
    "output": "Specifically methylates guanosine-37 in various tRNAs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQRTLLLAKIHNCTLTGANINYVGSISIDEILLEKAGILPYEQVQVVNSANGQRFITYAIPAPAHSGVIELNGGAARLGIIGDRLIIMTYGQFTPEELKNYSPTVVIVDEKNRLLEVRRYDDLLVKV",
    "output": "Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKLSLINRDIKRAKLADKYAAKRAELKAIIDDQSKTDEERYQARLKLQQLPRNANPTRQRNRCVVTGRPRGVFRKFGLTRHKLREMAMKGEIPGITKASW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAYIEGNTGKWEYVIGLEIHAQISSKSKLFSGSSTIFAANPNSQVSYVDAAMPGMLPVLNKHCVHQAIKTGLGLKAKINKYSVFDRKNYFYADLPQGYQISQFYYPIVQNGTMEIPTSTGDLKTIRINRLHLEQDAGKSMHDQSPHYSFIDLNRAGIGLMEIVTEPDISSPEEAAEFVKKLRNLLRYIGSCDGDMEKGSMRCDANISVRRSGEPLGTRCEIKNINSIRNIIKAIEFEAKRQVDLLESGEKIIQETRLFNADSGETRTMRLKEEALDYRYFPDPDLLPLVISDELINELKANLPELPDQKIEKYTKEFSLSKYDAEVIVADESVAEYFEKAANECNPKMLTNWLTSELFGQLNKASIGINECKITPSNFAKLVKLIENDTISGKIAKTVFEIMFETGKAPDKIVEEKGLVQVSDNNVLNTVIDEVIAENPESVEGYRSGKDKLFGFFVGQVMKKTGGKANPTLVNQLLKEKLSS",
    "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAAPTTEHAETIVPALCRRFGGETFVQQTTADGISTLWLPARILVETIRYLRSEIDRPYALLFDLTAVDERVRKHRDGMPASAYTVVYHLVSLERNADVRLKIALPETDPALPSIVAVCPAANWYEREVWDMFGIRFDGHPNLRRLIMPPTWQGHPLRKDHPARATEMEPFSLPDDVQQQEQEALRFVPEEWGMQRQSEDTDFLFLNLGPNHPSVHGVFRVALQLDGEEIVDAVPDIGYHHRGAEKMGERQSWHSYIPYTDRIDYLGGSMNNLPYVMAVEKLAGIEVPERARVIRVMISEFYRIASHLLFYGTFAQDVGQMSPIFYMFIDRERVFEIIESFTGARMHSSFFRIGGVAMDLPEGWDRLIREFIAYFPRRLAEYDKAVMANKLIQRRTRGIGAYTTTEAIDWSVTGAGLRATGLPWDYRKARPYSGYENFEFDVPTGTNGDCYDRCAVRVEEMRQSLRIIEQCVEHMPSGPYKAEHPLTTPPPKERTMHDIETLIQHFLSVSWGPVIPPGEVCVTIEATKGLNGYYLTSDGGTMSYRTRIRTPSFPHLQMIPLMSRGMMVADLIAILASIDFVMADVDR",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "EFFHGWYMEPLTKGRYPDIMRQIVGTRLPNFTEDEAELVAGSYDFLGLNYYVTQYAKPKPNPYPSEKHTAMDDAGVDLTFKNSRGEYPGPVFAEDANSYYYPKGIYYVMDYFKTKYGNPLIYITENGISTPGSESRCERIADYKRINYHCSHLCFLSKVIKEKGVNVRGYFAWALGDNYEFGKGFTVRFGLSYVNWDDLNDRNLKESGKWYQRFINGTAKNPVKQNFLRSSLSSQNQKKRLAC",
    "output": "Degradation of glucosinolates (glucose residue linked by a thioglucoside bound to an amino acid derivative) to glucose, sulfate and any of the products: thiocyanates, isothiocyanates, nitriles, epithionitriles or oxazolidine-2-thiones."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTTEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNKIQGIYTIPEAQIVFIDTPGIHKPKHRLGDFMVESAYNAMREVDATLFMVSADQKRGKGDDFIIERLKNNNSPVYLIINKIDKVHPDDLLSIIEDYSKQMDFKEIIPISATEGNNFEHLMDVLVEQMPEGPQYFPDDQITDHPEYFIVSELIREKVLLLTRDEIPHSVAVVVDSMKRDENDKVHVQATIIVERDSQKGIIIGKGGKMLKQIGTKARQDIEYLLDDKVYLELWVKVQKDWRDKKIYLQDFGYRKEEY",
    "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGFFKKKEKKAEFDVFRLYGLHHPEPGKCDEITTRGYSISMSVDKARRVIDQIRGRSYAETLMILELMPYRACYPIFKLIYSAAANASHNKQFNKANLIISKAEVNKGITLKKVKPRARGRSYMIKRPTCHITIVLRDITHFDSYDKFLESLTPKKLIALLGLMSTGRRRELLCGRFRENHKIKSFLYKIALFKRYEVM",
    "output": "Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEQVNELKEKGNKALSAGNIDDALQCYSEAIKLDPQNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNLQLKEGLQNMEARLAERKFMNPFNLPNLYQKLENDPRTRTLLSDPTYRELIEQLRNKPSDLGTKIQDPRIMTTLSVLLGVDLGSMDEEEEAATPPPPPPSKKEAKPEPMEEDLPENKKQALKEKEMGNEAYKKKDFDMALKHYDRAKELDPTNMTYITNQAAVHFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEERYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALELDSSCKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQKLMDVGLIAIR",
    "output": "Acts as a co-chaperone for HSP90AA1. Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MELRHLRYFVAVAQALNFTRAAEKLHTSQPSLSSQIRDLENCVGVPLLVRDKRKVALTAAGECFLQDALAILEQAENAKLRARKIVQEDRQLTIGFVPSAEVNLLPKVLPMFRLRQPDTLIELVSLITTQQEEKIRRGELDVGLMRHPVYSPEIDYLELFDEPLVVVLPVDHPLAHEKEITAAQLDGVNFVSTDPVYSGSLAPIVKAWFAQENSQPNIVQVATNILVTMNLVGMGLGVTLIPGYMNNFNTGQVVFRPIAGNVPSIALLMAWKKGEMKPALRDFIAIVQERLASVTA",
    "output": "Transcriptional activator of the hca operon for 3-phenylpropionic acid catabolism."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPRFVDRVVIHAKAGTGGHGCASVHREKFKPLGGPDGGNGGRGGSVILEVDPQVHTLLDFHFHPHLQAPNGTQGMGGHRNGANGDDLILKVPDGTVVLDDDGRILADLVGAGARFDAAAGGRGGLGNAALASRARKAPGFALLGEAGAEVDLTLELKTVADVGLVGFPSAGKSSLVSVLSAAKPKIADYPFTTLVPNLGVVTTGENSFVMADVPGLIPGAAEGRGLGLEFLRHIERCAVLVHVVDCATLEPGRDPVSDIDALENELARYQPTLQDDSVLGDLADRPRAVVLNKVDVPEADELADFVTEEVSQRGWPVFKVSTLTRDGLRPLTFALWEMIVAARAARPEPVKTRPVIRPIPVDESGFTVSADPQNPGGFVVRGVRPERWIRQTNFENDEAVGYLGDRLARLGVEDELLKLGAEPGCAVTIGDMTFDWEPQTPAGVDVTMSGRGTDARIDKTDRVGAAERRQARRVRRGQVEPE",
    "output": "An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQFYPRMMAQASHKAL",
    "output": "Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDTSHSDTVLIIDFGSQVTQLIARRVRAMGVYSEIVPFQSALGGINRIKPKAVILSGSPYSTLDNGSPRAPIEVFEAGIPVLGICYGQQVMCVQLGGKVEAGHEREFGRAFLEIKEESALFDGVWEKGSSQQVWMSHGDRVTALPEGFCVIGTSKGAPYAAISDEKRNFYAVQFHPEVVHTPDGEKLLQNFVCKISGIKNNWSMAAYRDQAIAAIREKVGKNRVICGLSGGVDSSVTAVLLHEAIGDQLTCIFVDHGLIRKNEAEEVLKLFRDNYNIELIHVNAADMFINALEGETDPEKKRKTIGRLFIEVFEEETKKIGGAKFLAQGTLYPDVIESVSAIGEAITIKSHHNVGGLPERMNMKLVEPLRELFKDDVRSLGRELGLPEEFIKRHPFPGPGLAIRCPGAVTREKIEILREADAIYLDEIRKAGLYDKIWQAFAILLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYPHDMDFLSRTAARIINEVRGINRVVYDITSKPPGTIEWE",
    "output": "Catalyzes the synthesis of GMP from XMP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGPGGRVARLLAPLMWRRAVSSVAGSAVGAEPGLRLLAVQRLPVGAAFCRACQTPNFVRGLHSEPGLEERAEGTVNEGRPESDAADHTGPKFDIDMMVSLLRQENARDICVIQVPPEMRYTDYFVIVSGTSTRHLHAMAFYVVKMYKHLKCKRDPHVKIEGKDTDDWLCVDFGSMVIHLMLPETREIYELEKLWTLRSYDDQLAQIAPETVPEDFILGIEDDTSSVTPVELKCE",
    "output": "Required for normal mitochondrial ribosome function and mitochondrial translation . May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable). May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome . May function as a ribosomal silencing factor (Probable)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTNLQELPSRGHLLTEQINPASQNLDQLTPLELVDLFNQEDAHTLRAIAQAREALAQTISATAARLRQGGRLFYIGAGTSGRLGVLDAAECPPTFCTPPHLVQGILAGGDAALVRSSEGLEDRYEDGAAVVGDRQITAQDVVIGISAGGTTPYVHGALDAAQGVGALTVFMACVPVEQVQRSADIDIRLLVGPELLAGSTRLKAGTATKMALNIISTGVMVQLGKVYGNRMVDVAVSNRKLLDRALRILTDVTGMDRAAAAALLERSGYQVKRALLMHWTGLDAPAAQALLDQQNGQLHAARSAALDP",
    "output": "Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSAEVPEAASAEEQKEMEDKVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPTAAPDKTEVTGDHIPTPQDLPQRKPSLVASKLAG",
    "output": "Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRILLSNDDGYLAPGLAALYEALRPLAEILVMAPEQNCSGASNSLTLSRPLSVSRSAATGFYYVNGTPTDSVHVALTGMLDTKPDLVVSGINNGQNMGDDTLYSGTVAAATEGIMFGVPAIAFSLVHKEWAHLGDAARVAAEIVRHYLDHPLPGQPLLNINIPNLPYEELKGWRVTRLGKRHPSQPVIRQTNPRGEPIYWIGAAGDALDASEGTDFHATASGYVSITPLQLDLTHTQMLAATRDWARAGSGAS",
    "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNPIVKSFEYGQHTVTLETGVIARQADAAVLASMGDTTVLVTVVGKKAEEPGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSESETLIARLIDRPIRPLFPNGFKNEVQVIITVVSVDPEINPDIISMIGTSAALAISGLPFNGPLGVARVGYTNGEYVLNPDVTQLVDSELDLVVAGTEGAVLMVESEAASLPEEVMLGGVVYGHEQQQVVINAISELKAEASKPAWDWTAPVQDQELVAKIKDLAEAGLTEAYQIEVKQDRYTQVGVIKSAAKEALLAENPEADLREIDGLLGSLEKKVVRSRIIAGNPRIDGREPDMVRALNVMAGVLPRTHGSSLFTRGETQALVTCTLGTERDAQKVDSIMGEYTNRFMLHYNFPPYSVGETGFVGSPKRREIGHGKLAWRGINAVMPSAEEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTRDGITALQMDIKIEGITKDIMQIALQQAYGARVHILNVMDQAIGSHREDISDHAPRITTLKINPEKIRDVIGKGGATIRALTEETGTTIELEDDGTVKIASSNGEATKEAIRRIEEITAEVEVGTVYNGKVVRIVDFGAFVTILPGKDGLVHISQIAEERVANVSDYLEVGQEVKVKVMEVDRQGRVRLSMKEAAPKAEAPAAE",
    "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MASSSNWLSGVNVVLVMAYGSLVFVLLFIFVKRQIMRFAMKSRRGPHVPVGHNAPKDLKEEIDIRLSRVQDIKYEPQLLADDDTRLLQLETQGSQKIPFHAEGRHPCSLMGKNFRSYLLDLRNTSTPFKGVRKALIDTLLDGYETARYGTGVFGQSEYLRYQEALSELATVVKARIGSSQRQHQSAAKDLTQSPEMSPTTIQVTYLPSSQKSKRPKHFLELKSFKDNYNTLESTL",
    "output": "General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLVSTLIQDQPDQPVEDPDPEDFADEQSLVGRFIHLLRSEDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAYQLAFRYKENSKVDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLRRESPESEGPIYEGLIL",
    "output": "Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The CSC seems to associate with the cytoplasmic domain of cargo proteins predominantly via VPS35; however, these interactions seem to be of low affinity and retromer SNX proteins may also contribute to cargo selectivity thus questioning the classical function of the CSC. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway . The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5 (Probable). Required for retrograde transport of lysosomal enzyme receptor IGF2R and SLC11A2. Required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA) . Required for endosomal localization of WASHC2C . Mediates the association of the CSC with the WASH complex via WASHC2 . Required for the endosomal localization of TBC1D5 .; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDKDEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKENGIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFDDLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNEVDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQALAVKMYEQAAAAQQAAQGTEGAQANDSANNDDVVDGEFTEK",
    "output": "Acts as a chaperone."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTEKVKKLSPRRRARECAVQTLYSWAISKNAPEEIELNFIVDQDNEMKGVDMPYFRKLFRQTVDHVEIVDSIMAPYLDRDNVELDPIECAILRLAVYELKFELDVPYKVVINEAIEVAKVFGAEESHKYINGVLDKIAPALSRK",
    "output": "Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLKLIIPTIMLLPLTWFSKKRMIWINTTTHSLIISTIPLLFFNQINNNLFSCSLSFSSDPLTTPLLMLTAWLLPLTIMASQRHLSNEPPSRKKLYLSMLISLQISLIMTFSATELIMFYIFFETTLIPTLAIITRWGNQPERLNAGTYFLFYTLVGSLPLLIALIYTHNTLGSLNILLLTLTAQELSNTWANNLMWLAYTMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRLTLILNPLTKHMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVVTAILIQTPWSFTGAVILMIAHGLTSSLLFCLANSNYERTHSRIMILSQGLQTLLPLMAFWWLLASLANLALPPTINLLGELSVLVTSFSWSNTTLLLTGFNMLITALYSLYMFTTTQWGSLTHHINNMKPSFTRENTLMFMHLSPILLLSLNPDIITGFTS",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAYPLQMGLQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETVWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTQELKPGELRLLEVDNRVVLPMEMTIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMTMRPGLYYGQCSEICGSNHSFMPIVLELVPLSHFEKWSTSML",
    "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIEADRLIAPISNHFKDEEVIDRAIRPKKLADYQGQDHVRDQMEIFIQAAQMRQEALDHLLIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPMVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEYYKVADLQHIVQRSAQCLGLSMDSEGALEVARRARGTPRIANRLLRRVRDYAEVKGDGHICAQTADRALNMLDVDHQGFDYMDRKLLLAIMEKFSGGPVGIDNLAAAIGEEKDTIEDVLEPFLIQQGYLQRTPRGRIATDRAYLHFGIEK",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKTLLLTLVVVTIVCLDLGYTLTCLICPEKYCNKVHTCLNGEKICFKKYDQRKLLGKGYIRGCADTCPKLQNRDVIFCCSTDKCNL",
    "output": "Binds with low affinity to muscular (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and very low affinity to neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMKELHPELRENVRLLGELLGQSIRYHLGDEIFNKIEKIRIAAKADRNAEISQRKQLKEVLSGLNDEELAPVARAFNQFLNLTNIAEQYHIVRRRAPASELVDNRLDTIEVVFDRLIGQGVSKDKFFAQLADLNLEFVLTAHPTEITRRTLIQKYDQISECLESLDRSDLLDEEYAKIVERLRRLITEAWHTDEIRYERPTAVDEAKWGFAVIENSLWQAVPDFMRQMDAALLERFGEGLPINVNPVRFASWMGGDRDGNPNVTSEVTREVFLLSRWMAADLYLRDIEALRSELSMTACNGELARASGQSREPYRKILAKLRSRLEATRAWAAEALDSTKKPAAEVLLNNAELIEPLMVCYRSLRDCGMEVIANGPLLDVIRRAQCFGLQLVRLDIRQDSERHSDVMKEICAYLGIGDYSQWTEEEKQAFLIRELEGRRPLLPKEWPASAEAREVLDTCRVVAMQPPEGLASYVISMASDPSDVLTVILLLRESGMRHHIPIAPLFETLSDLQGAADSIGRLLDLPWYREYIGGKQEVMIGYSDSAKDAGQMAAAWAQYQAQEALVKVAAKHDVKLTLFHGRGGTVGRGGGPANRAILSQPPGSVAGNFRITEQGEMIRFKFGQPKVAKQSFNLYLGAVLEASLVPPPEPEPAWREMMDKLSHLAVNSYREVVRERPGFVEYFRSATPEQELGKLALGSRPARRKASGGVESLRAIPWIFAWTQMRLMLPAWLGSDTALQTAVDDGGADTLKAMLTGWPFFETHVDMLEMVLSKVDPEIARFYEERLVKPELHPLGDELRRRAGCAVRLINELKGQDELLLDNPVFMHSLQVRNPYTDPLHFLQVELLVRDRAEGETNKETVEKALKVTMAGVAAGMRNTG",
    "output": "Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNERSLRVLEYNKIIHMLEDKCTSSLGREKLKELKPISNFEQITTWQKETSEAQSILIHRGNIPLGGIHDVSQYLRRTEIGSYLDPGQLLQLKETLAAARRMKTFLKDDKKESTYPIIQELGNNISSLKHIEDKIELCIISETELSDNASPELRNIRRQISSKNDAIRNKLNSIITSASNQKYLQDPIITMRQDRYVVPVKQEHRGNIPGLIHDQSSSGATIFVEPMAVVELNNQLKELRLKEQVEIERILMEIAAMIAERSDDIKSNQIILKELDFIFAKGKLSVEMRAVEPVLNTNKKISIKNGRHPLLPSNKVVPNTMWLGEDFHTLVITGPNTGGKTVTLKTLGLLTLMAQSGLHVPADYGTKLAIFDQVFADIGDEQSIEQSLSTFSSHMTNIVNIMDNVTEQSLVLFDELGAGTDPTEGAALAMAILNSLREMGTVTVATTHYSELKQYALSTEGVENASVEFDVNTLSPTYKLLIGVPGKSNAFEISRKLGLSDFLIQRSKELLTREDIQFEDLLQNIEKNRSTAEKEKDEAARLRMETQKLREEYYEKKQQLQTQKEKLISDAKREAYKIVKQAKLDADEIVENLKTLRAELEEKEMNKKIEEARKNLSDQMGKLAENMGEKLVLKTNKKPPKNLKIGESVNILSLNQIGYVILPEDANGEVQLQVGIMKVNMHVSNLERIKEEKDTKKTGVGKIVKSKAENIKMEIDVRGQNLEEAMLNVDKYLDDAYIAGLTHVTIIHGVGTGVLSAGLKQMLKKHKHTKSFREGEYGEGGMGVTIVHLK",
    "output": "Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEQYTIKFNQINHKLTDLRSLNIDHLYAYQFEKIALIGGNGTGKTTLLNMIAQKTKPESGTVETNGEIQYFEQLNMDVENDFNTLDGSLMSELHIPMHTTDSMSGGEKAKYKLANVISNYSPILLLDEPTNHLDKIGKDYLNNILKYYYGTLIIVSHDRALIDQIADTIWDIQEDGTIRVFKGNYTQYQNQYEQEQLEQQRKYEQYISEKQRLSQASKAKRNQAQQMAQASSKQKNKSIAPDRLSASKEKGTVEKAAQKQAKHIEKRMEHLEEVEKPQSYHEFNFPQNKIYDIHNNYPIIAQNLTLVKGSQKLLTQVRFQIPYGKNIALVGANGVGKTTLLEAIYHQIEGIDCSPKVQMAYYRQLAYEDMRDVSLLQYLMDETDSSESFSRAILNNLGLNEALERSCNVLSGGERTKLSLAVLFSTKANMLILDEPTNFLDIKTLEALEMFMNKYPGIILFTSHDTRFVKHVSDKKWELTGQSIHDIT",
    "output": "Confers resistance to 14-membered ring macrolides (like erythromycin) and to B streptogramins, by acting as an ATP-dependent efflux pump."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MHAFLGNAQLPSTPRGDRLEFSEWYAEVLRSAEIMDVRYPVKGMYVWLPYGFEIRQRVVEKLRRKLRETGHEEVLFPTLIPETQLKKESEHIAGFEDEVYWVTHGGLKELDEKLALRPTSETAIYPMFALWIRSHADLPLKIFQIVNTFRYETKHTRPLIRMREITTFKEAHTAHATEEEAEEQVKEAVEIYSSFFDELGIPYIASVRPEWDKFPGAEYTVAFDTLMPDGRTLQIGTVHMLGQNFARTFEVTYETEEGDQEYVYMTCYGISDRVVASMIAIHGDERGLVLPPDVAPYQVVMVPILKKGVRRKILERAAEVEEMLREEGVRVKVDDRDMSPGRKFHYWELKGVPLRIELGARELEEGTAVVFRRDELERETYAFEELPDVVPELLEDIAMELRKRAREKFEKGIFRTDSPEEARRLVGEGIVETGWCGSERCGVRMEEEFGGDVLGTPYPEEDTEFERCPICGETAEYTVRIAKTY",
    "output": "Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEDPQPLPQSELPLCDSLIIWLQTFKTASPCQDVKQLTNGVTMAQVLHQIDVAWFSESWLSRIKDDVGDNWRIKASNLKKVLHGITSYYHEFLGQQISEELIPDLNQITECADPVELGRLLQLILGCAVNCEKKQEHIKNIMTLEESVQHVVMTAIQELMSKEIVISPASDTVGELEQQLKRALEELQEAIAEKEELKQRCQELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTMVAKKYFHVQLQLEQLQEENYRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEVYRQKLQDLNDLRKQVKSLQETNMMYMHNTVSLEEELKKANAARAQLETYKRQVQDLHTKLSSESKRADTLAFEMKRLEEKHETLLKEKERLIEQRDTLKETNEELRCSKAQQDHLNQADASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGTENERIEQLQEQLEQKHRKMNELETEQRLSKERIGELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDISQNAQKISELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKLRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGASACKDSVAAAPARSFLAQQRHITNTRRNLSVKVPAAASD",
    "output": "Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (By similarity). Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSGPNRTYSFGEGDDSLAHPSSRTHAMHSQYDDVSPISDGARMNPMNGQGMDHGLASVLEDGRQGWGRSPEPSPSLLTGSSATPGMDNLGPGAVGGGISGIALSVANSHDRLSGVEALMGTDGQEANIPAERGLSTTGSDNPYVPEPPEHRYSYGSNIALGAAAAPAGQLTPGQSVSHLSSTNPSQRNLYDIPYQDVGGLNAGPYQRHSAYSSNDLPVDINPDEIVDDGDDGFVPAPNSGSGARKSQAIPAAAGGAAAGGVLGNLGGLFGGKSAADTSYGPVPGAGLEAGEKGRWVKPKPGGGNKKRGWIVGAILAFIIIGAIVGGAVGGTIGHRGNEEPSSASSASSSSTQTATEDTSVNGDLDKNSAEIKALMNNKNLHKVFPGIDYTPWGVQYPLCLKYPPSQNNVTRDMAVLTQLTNNVRLYGTDCNQTEMVLHAIDKLEIKDMKIWLGVWIDSNETTSRRQIDQLYKIIDDAKDISIFNGAIVGNEALYRAGSDKTSAQTTLINYMQEVKDHFKKKNIDLPVATSDLGDNWDATLVQAADVVMANVHPFFGGIPVDQAAAWTWRFWQDHNVALTKGTNKKQIISEVGWPSGGGNDCGQGANCPNDTAGAVAGVDELNKFMEDWVCQALDNGTDYFWFEAFDEPWKIVYNTGKENWEDKWGLMDSARNLKPGLKIPDCGGKTAT",
    "output": "Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGNILLQLLAVVALCIAPARSDWLPGTATFYGGADGSGTMGGACGYGNLYDQRYGINNAALSTPLFNDGASCGQCYLIICDYGKAPDWCKLGKAITVTGTNYGGWCNATRPYFDMSQPAWENIGIYSAGIVPILYQQVKCWRYGGVRFIINGFNYFELVLVTNMAGSGSIVSMSVKGSCTGWIQMTRNWGANWQCLAGLAGQALSFNVTSTGGQTIVFDDAVPAGWSFGQTFSTYHQFDY",
    "output": "May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. May be required for rapid internodal elongation in deepwater rice during submergence (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATNKERLFAPGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSKPGPHPKASSEDEAPGGQGKRGQSPQPDQGP",
    "output": "Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (By similarity). Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADTANYINDRFQTFMNGLGDRYEPYVREHLSKVYMVLGSTAAATAMGAMLQMRDFLDLGVLAAVATLVLVLGLHFYKDDGKNYYTRLGMLYAFGFCSGQTLGPLLGYICSINPAIILSALTGTFVTFISLSLSALLAEQGKYLYLGGMLVSVINTMALLSLFNMVFKSYFVQVTQLYVGVFVMAAFIVYDTQNIVEKCRNGNRDVVQHALDLFFDVLSMFRRLLIILTQKEERKQNERRQNKTK",
    "output": "Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling . Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDPNCSCPTGGSCSCAGSCTCKACRCTSCKKSCCSCCPAGCARCAQGCICKGASDKCSCCA",
    "output": "Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRRTVPRGTLRKIIKKHKPHLRLAANTDLLVHLSFLLFLHRLAEEARTNAFENKSKIIKPEHTIAAAKVILKKSRG",
    "output": "Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPW has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSITLSDSAAARVNIFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPMAEDTVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFSNPNVKDECGCGESFHV",
    "output": "Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPTINQLVRRPRRPRESANKAPALQHNPQKRAVCVKVYTTTPKKPNSALRKVARVRIAGYGSEVIAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDAKGVQGRKKARSKYGVKRGV",
    "output": "With S4 and S5 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEESQGYLELYKSRQHDFLYPLIFQEYIYVLAHDHGLNRSILLENLGSDNKFSSLIVKRLITRMYQQNRLIISANDSNRNPSLGHNKDLYSQIISEGFAVIVEIPFPLRLVSSLERKEIVKSHNLRSIHSVFPFLEDKFLHLNYVSDILIPHPIHLEILVQTLRYWVKDASSLHLLRFFLYEYRNWNSLINPKKSIFVFSKRNQRLFLFLYNSHVYEYESVFVFLRTQSSHLRSTSSGALLERIYFYGKIKHLVEVFANDFQAILWLFKDTFVHYVRYQGKSILASKGTPLLMNKWKYYLVNFWQCNFYVWSQPVRIYINQLSNHSLYFLGYISSVGLNPSVVRNQMLENSFIIDNAIKKFDIIVPIIPLIGSLAKAKFCNVLGHPISKPARADSSDSDIIDRFVRICKNLSHYHSGSSKKKSLYRIKYILRLSCARTLARKHKSPVRAFLKRLGSELLEEFLTEEEQVLSLIVPASSTSRRLYRGRIWYLDIICINDLANHE",
    "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLDKSRLRIAMQKSGRLSKESQKLLEQCGIKINLQQQQLLAFAENMTIDIMRVRDDDIPGLIMDGVVDLGIIGENVLEEALLTRQSQGDNPCYVTLRRLDFGDCRLSMALPMDKPWNGPKCLQGKRIATSYPHLLKQYLDKLGINFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRSGNLSKTKQSLIDKLMIRIQGVIQARESKYIMLHAPAERLEEIINLLPGAESPTVLPLAGNQHRVAIYMVSNEALFWETMENLKNLGASSILVLPIEKMME",
    "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSISKDDILNAVAEMSVMDVVALIEAMEEKFGVSASAAVAAAGPAEAADEQTEFNVVMTSFGEKKVAVIKAVRGATGLGLKEAKDLVESLGVVKEGVEKAEAEELKKTLEEAGASVEIK",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLILVTNDDGINAPGIKALSRSLARVGRVAVVAPEKERSAIGHGITMHKPLRATEVTWEGPVEMALAVNGTPADCVKLALDALLDEEPSLVVSGINMGANLGTDVLYSGTVSGALEGCINGRPSLAVSLAGEGGVDFSFAADFTSRLAGVIIKRGLPAGTLLNLNIPCLPPGEIKGLAITRLGRRRYCNTITRRLDPRGRAYYWLAGEVEDLDQEPDTDIGALGQGRISITPLHLDLTNYSYQQELAAYLSFLWPGQGNR",
    "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQVREQVFDLVLCDVRMAEMDGIATLKEIKALNPAIPVLIMTAYSSVETAVEALKTGALDYLIKPLDFDNLQATLEKALAHTHSIDAETPAVTASQFGMVGKSPAMQHLLSEIALVAPSEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHEKGAFTGADKRREGRFVEADGGTLFLDEIGDISPMMQVRLLRAIQEREVQRVGSNQIISVDVRLIAATHRDLAAEVNAGRFRQDLYYRLNVVAIEVPSLRQRREDIPLLAGHFLQRFAERNRKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISERELPLAIASTPIPLGQSQDIQPLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR",
    "output": "Member of the two-component regulatory system ZraS/ZraR. When activated by ZraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MANRRVGRGCWEVSPTERRPPAALRGPATEEEASSPPVLFLSHFCRSPFLCFGDVLLGDSRTLPLALDNPNEEVAEVKISHFPAADLGFSVSQRCFVLQPKEKIVISVNWTPFKEGRVREIMTFLVNDVLKHQAILLGNAEKQKKKKRSLWDTIKKKKISASTSHNRRVSNIQNVNKTFSVSQKVDRVRSPLQACENLAMNEGGPPTENNSLTLEENKIPISPISPAFNECHGATCLPLSVRRSTTYSSLHASENRELLNVDSANVSKVSFNEKAVTETSFNSINVNDQSGENSKLILTPNYSSTLNITQSQINFLSPDSFVNNSHGANNELELVTCLSSDMFMTDNSKPVHLQSTTAHEIYQKILSPDSFIKDNYGLNQDLESESVNPILSPNQFLKDNMAYMCTSQQTYKVPLSNENSQVPQSPQDWSKSEVSPCIPEYQGSKSPKAIFEELVEMKSNYYSFIKQNNPKFSAVQDISSHSHDKQPKRRPILSATVTKRKPTCTRENQTEINKPKAKRCLNSAVGEHEKVIHNQKEKEDFHSYLPVIDPVLSKSKSYKNQIMPSLTTASVARKRKSDGSMEDANVRVAVTEHTEEREIKRIHFSPSEPKTSAVKKTKNVITPISKCISNREKLNLKKKTDLLIFKTPISKTSKRTKPIIAVAQSNLTFIKPLKTDIPRHPMPFAAKNMFYDERWKEKQEQGFTWWLNFILTPDDFTVKTNISEVNAATLLLGVENQHKISVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVKAIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETIYGELISLEDNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPHLYRDGHEGALSKFTLKKLLLLICFLDYAKISKLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDEFDFAITNLAVDLQCGVRLVRTMELLTQNWNLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTISLLSCHSDALINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSDGRVLCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTSELYKELLENEKKNFQLIRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWKRRKMQSQVKATVILQRAFREWHLRKRAKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKLQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMCKAIMVIQNYYHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHRQHQEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMHREKYLTILKAVKILQASFRGVRVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFKRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKKMREMHRAATFIQATFRMHRVHMRYQALKQASVVIQQQYRANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLQLRKAAITIQSSYCTIRRLMVKKKLQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQTAYKGMKARQHLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLPVQKSVRTIQAAFRGMKVRQKLKIVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASDLACSQEAECHSQSRAAVTIQNAFRRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQKTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQQKKFIQKYSIKKIEHEGQECLSQQNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRLSLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCENMAQSGAISKIFVLIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDTLLELLQIYREKPGNKVADKGGSIFTKTCCLLAVLLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILHKQKKNSSISIPFIPETPVRTRIVSRLKPDWVLRRDNMEEITNPLQAIQMVMDTLGIPY",
    "output": "Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIAKTTNLNLFYGKKQALFDINMQIEQNKITALIGASGCGKSTFLRCFNRMNDKIAKIDGLVEIEGKDVKNQDVVALRKNVGMVFQQPNVFVKSIYENISYAPKLHGMIKNKDEEEALVVDCLQKVGLFEEVKDKLKQNALALSGGQQQRLCIARALAIKPKLLLLDEPTSALDPISSGVIEELLKELSHNLSMIMVTHNMQQGKRVADYTAFFHLGELIEFGESKEFFENPKQEKTKAYLSGAFG",
    "output": "Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVNEEMESSLKVIDVARVTPSNSDSSESLTLPLTFFDLLWYKLHAVERVIFYKLTDASRPFFDSVIVPNLKTSLSSSLSHYLPLAGKLVWEPLDPKPKIVYTPNDAVSFTVAESNADFSRLTGKEPFPTTELYPLVPELHVSDDSASAVSFQVTLFPNQGFCISVNAHHAVLDGKTTTNFLKSWARTCKNQDSFLPQDLIPVYDRTVIKDPMDLDTKILNAWHRVAKVFTGGKEPENPKSLKLLWSPEIGPDVFRYTLNLTREDIQKLRERLKKESSSSSVSSSPKELRLSTFVIVYSYALTCLIKARGGDPSRPVGYGFAVDCRSLMVPPVPSSYFGNCVSACFKMSLTAETFMSEEGFLAAARMVSDSVEALDENVALKIPEILEGFTTLSPGTQVLSVAGSTRFGVYGLDFGWGRPEKVVVVSIDQGEAISFAESRDGSGGVELGFSLKKHEMDVLVDLLHKGLEN",
    "output": "Malonyltransferase acting on xenobiotic glucosides. Has activity toward 2-Naphthol glucoside (2NAG), 1-Naphthol glucoside (1NAG), kaempferol 7-O-glucoside, kaempferol 3-O-glucoside, hydroxycoumarin glucosides, phenol-glucosides and isoflavone glucoside (daidzin), but not toward 4-coumaroyl glucoside, kaempferol 3,7-O-diglucoside, salicylic acid glucoside and phlorizin. In vivo, seems to be involved in the malonylation of 2-Naphthol glucoside while PMAT2 would be involved in the malonylation of 4-methylumbelliferone glucoside or 4-nitrophenyl glucoside."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLILPIVKGEYKKDYNLKHLTWFKVGGNAEIFFKPLDSEDLKSFLIQNKQKLPIKTFGAGSNIIIRDGGIEGVVIKLGQNFSNIEFIDNHLIVGSSCLNYNLAKFCQANAISGFEFLVGIPGTIGGGVAMNAGAYGSEFKDIVVQIEAIDFAGNFLTFTNEEIGFKYRSNNLPKNLIILKVIFKINKGDSENILLRMNEINNARSSTQPIKERTGGSTFANPEGCKSWELIDKAGLRGYRIGGASMSELHCNFMINNGDATAKDLEDLGNFVQQKVCEDSGVKLEWEIKRIGRHP",
    "output": "Cell wall formation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKLQLIAVGTRMPDWVTRGFEEYQRRFPRDMALELIEIPAGKRGKNADIVRILQKEGEQMLAAIPKGNHIVTLDLPGKNWTTPELATAMNKWQLDGRDVSLLVGGPEGLAPACKEAAHQSWCLSALTLPHPLVRIVVAESLYRAWSVNTNHPYHRE",
    "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN",
    "output": "Involved in allosteric regulation of aspartate carbamoyltransferase."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTTPPLAQFSGQQQQQTQAARDVNTASLCRIGQETVQDIVLRTMEIFQLLRNMQLPNGVTYHPNTHQDRLGKLQEHLRTLSVLFRKLRLVYDKCNENCAGLEPIPSEQLIPYVEDDSSKLEDRMANQLRAASEERREVLEVNKKLKQKNQQLKMIMDQLRNLIWEINSMLAVRS",
    "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFPIASRRILLNASVLPLRLCNRNFTTTRISYNVIQDLYLRELKDTKLAPSTLQDAEGNVKPWNPPQKPNLPELELQGPEALKAYTEQNVETAHVAKESEEGESEPIEEDWLVLDDAEETKESH",
    "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MILPSEKSATDVAAQCFLNALIRETKDWQLAEYPPDELIIPLDEQKSLHFRVAYFSPTQHHRFAFPAHLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCETFHQRVLESYAHTQQTIDARHDWAILREKALNFGEAEQALLTGHAFHPAPKSHEPFNRQEAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLRPWQGEYLFQQVWCQALFAKGLIRDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSVRTLSVKEVERGMRLARLAQTDGWQMLQARFPTFRVMQEDDWTGLRDLNGNIMQESLFSPAWKTLLLEQPQSQTNVLVSLTQAGPHGGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATEWLDTIDEAQAENIFTREQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLMARVRTLLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV",
    "output": "Catalyzes the attachment of a first N-acetyl-N-hydroxylysine to a carboxylic group of citric acid to yield N-citryl-N-acetyl-N-hydroxylysine. Involved in the biosynthesis of the siderophore aerobactin which is a chelator that mediates the high-affinity iron transport systems induced under iron-stressed conditions."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "FIGPIISALASLFG",
    "output": "Antimicrobial peptide. Active against the Gram-positive bacterium S.aureus (MIC>60 uM) and the Gram-negative bacterium E.coli (MIC>60 uM)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDLKFATFSSEIELPFYSALFSSKLDHDKLDSSARPVLGLYEPRSQANPEASTRMQILGSALTSDQDESGPLGMTRAEGYIKNVNTIEEFKNTDKNAMIKKAGEQIWDAIQDGTIYSCPSLLASFRILSYADLKKYRFTYWFAFPALHSEPQWKRTEPIGRLNSDESTALVERIGTWRYMVDRREHGFFLAKKVRGEASGPRSSLDDPGVDIGYRWDIGSLRDFETGFFNDAAEEDRYVAFVDPSNYPEYPSWPLRNLLILVRQRYRLNKVQILCYRDTQPRRHEARSIILPLAMDQVGDVELKSMPKVTGWERNGNGDLRPRVANLAEYMDPTRLADQAVDLNLKLMKWRLAPNLDLDTIKNTKCLLLGAGTLGSYVSRNLLGWGVRKITFIDYGSVSFSNPVRQPLFKFEDCHNGGKPKAIQAAEALREIYPGVDVEGYALSVPMLDHPIHNEAKTKAEFDKLKELIDSHDAIFLLMDTRESRWLPTLMGKAANKIVMNAALGFDTYVVMRHGAKPLDDSEDTLGCYFCNDVVVAADSMKDQTLDQQCTVTRPGVAAIASALLVELLTSILQHPLKQHAPAPISAGTGSAVSYERDPHDHPLGLVPHQVRGFLSNFQNMIIRGKSYPQCSACSKPVLDAYREGGWDFVKTALASRDYVAELSGLAEVQRLAEKAAAEMQWSEDEEGMGEEEGEGELI",
    "output": "E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy . Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity). Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity). Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity). Required for normal mycelial growth and conidiogenesis ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEQCVADCLNSDDCVMIVWSGEVQEDVMRGLQVAVSTYVKKLQFENLEKFVDSSAVDSQLHECSVILCGWPNSISVNILKLGLLSNLLSCLRPGGRFFGRDLITGDWDSLKKNLTLSGYINPYQLSCENHLIFSASVPSNYTQGSSVKLPWANSDVEAAWENVDNSSDANGNIINTNTLLQKSDLKTPLSVCGKEAATDSVGKKKRACKNCTCGLAEIEAAEEDKSDVPISSCGNCYLGDAFRCSTCPYRGLPPFKPGERILIPDDVLRADL",
    "output": "Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIMTQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSNSELVAGDSNFKITVKVDKDNGQIIIRDNGIGMNKDDLIENLGTIARSGTANFLKSLSGDSKKDNMLIGQFGVGFYSSFMVADKVTVTSRKAGEDKVHIWESDGLGEYTVSDSDKEFTRGTEIVLHIKKEEDTFLDHFRLKHIVKSYSDHIAVPIYFFDEAGNNEIQLNSASALWTRPKSEITEEQYKEFYKSLSYAVDDPWITMHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKRRVKLYIKRVFISDENIDLIPSYLRFLRGVVDSEDLPLNISRESLQHNSVLEKIKNAITKRVLGELRKKKEESPEEYNKFWANFGGALKEGLCEATTDHEKLLEVCIFRSALHNKMISLDEYIANFKEGQSTIYYLSGDNPDKLLSSPQIEGLLSKEIDVLLFTDTVDDFWVNVNSKYKEHAIKSATRSDIDVEQTTSQSEEKNTDSKKSDDEYKLLTDYFKETLGELVKEVKISKKLTSSPACLAVSDAAMDIRMERFLIEQKQIANASAKNLELNPKNKIIEKIFNDLKANNKNNEELVNLIFDQACILEGEPVADTGAFSKRLNDIVQKAIL",
    "output": "Molecular chaperone. Has ATPase activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MASSISHRKTRDEYKKEKELDEARKAGNAPAELDEEGKEINPHIPEYILKAPWYLNANKPSLKHQRGVTKKEMDKGWYLRGATTGEAATKFRKGACENCGAMTHKTKDCCERPRKLGAKFTNDDIKPDEVIQKLELDYDSKRDPYNGYDPSSYKEVMDIYEKADTERKKKKLQELIKQHGGGGDKKTPDVDETLSKELMDNEEKEGSYDSETVAPIQKLDQKSRTTIRNLRIREDTAKYLYNLDVNSAFYEPKSRSMRDNPLPNANPNDIKFAGDNFARTSGETKEFRDLQRFAWEAQEKGQDVDISSAPSQAALLHADFLRKKEQLKQQTRNQLLTKYGGEEHLLKQEEIDKVPQSEIYTEYSSSGKLIKGEEKIVKSKYEEDVFLNNHKSIWGSYWENGQWGFACCRQLIKNAYCTGEKGKLLREKQLQQQQQHHIQQENQQDDDDNNTTTTTTTTTTSLLEQHLNKSNEDNDKHNKKEGKRKDKKERKEKEEKLKKALKDQDEENKKSVEKDERNIKYNSLSADDYNVSEEQMEAYNLKRKRSDDPMANFKDDSD",
    "output": "Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSIIQEFKEFAIKGNMMDLAIGVIIGGAFGKIVDSLVKDIIMPLITVITGGGVDFSQKFIVLGANPNNLQSLDALQKAGINVLTYGNFLTILINFLILAWVVFLMVKLLNKLRRDKNEPEAPAATPEDIQLLREIRDELKKQA",
    "output": "Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGKSPAQTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDTDENGVCTATEDYKDVAAVADQIGVPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMELGADYVATGHYAQVRTDENGIVHMLRGADNNKDQTYFLSQLTQEQLKKTMFPLGHLEKPEVRKIAEKAGLATAKKKDSTGICFIGEKNFKKFLGEYLPAQPGKMMTLDGIEMGNHAGLMYYTIGQRGGLGIGGQHGQLTSDPWFVVGKDLTTNTLYVGQGFHHEHLYSTSLDASDLSFTREMPETFDLHCTAKFRYRQEDTGVTIHVNGDKVTVDFDEPVRAITPGQAVVFYDGEECLGGAMIDVAYKAQKVMQYQ",
    "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKAKFERSKPHVNVGTIGHVDHGKTTLTAAISHVLAKTYGGEAKDFSQIDNAPEERERGITINTSHIEYDTPSRHYAHVDCPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVPFIIVFMNKCDMVDDAELLELVEMEVRELLSEYDFPGDDLPVIQGSALKALEGEPEWEAKILELAAALDSYIPEPERDIDKPFLMPIEDVFSISGRGTVVTGRVERGIVRVGDEVEIVGIRTTTKTTCTGVEMFRKLLDEGRAGENCGILLRGTKRDDVERGQVLSKPGSINPHTTFESEVYVLSKEEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMKVTLICPIAMDEGLRFAIREGGRTVGAGVVAKIFA",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKNPMLEAVSLVLEKLLFISYFKFFSSGAPGQDKAGNTLYEISSFLRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDKGRTQKVVSNKRLILGVIGRVASIRVDTVEDFAYGAEILVNHLDRSLKKKALLNEEVAQRAEKLLGITPYSLLWNNCEHFVTYCRYGTPISPQADKFCENVKIIIRDQRSVLASAVLGLASIFCLGLTSYTTLPAIFIPFLLWMAG",
    "output": "Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters . Retinyl esters are storage forms of vitamin A (Probable). LRAT plays a critical role in vision (Probable). It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments (Probable). Required for the survival of cone photoreceptors and correct rod photoreceptor cell morphology (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTNALLEDLKWRGLIYQQTDESGIENILNKEQVTLYCGADPTADSLHIGHLLPFLTLRRFQEHGHRPLVLIGGGTGMIGDPSGKSEERTLQTEAQVETNVQGINKQMHKIFEFDTEKGAKLVNNKDWLGQISLIDFLRDYGKHVGVNYMLGKDSIQTRLEHGISYTEFTYTILQAIDFGHLNRTYNCKVQVGGSDQWGNITSGIELMRRMYGQTEAYGLTIPLVVKSDGKKFGKTEGGAVWLDAAKTSPYEFYQFWINTTDDDVIKFLKYFTFLEQEEIEALEKSLNEAPHLREAQKALAENVTRFIHGQDALDDAIRISQALFAGDLQSLSASELKEGFKDVPQVELSSETRNIVEVIVETGISSSKRQAREDVNNGAIYINGIRQQDVNYELTSEDKIENEFTIIRRGKKKYFMVNYK",
    "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVGYDPKPDGRNNTKLQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRRDPNAKYHGIFQASRQILQEEGLTAFWKGHIPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACTATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAMPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFWYEFFCNVFHCMNRTASQR",
    "output": "Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria. It is not clear if the antiporter activity is affected by the membrane potential or by the proton electrochemical gradient."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSRMVQCVKLGHEAEGLDRPPYPGALGARIYQEVSKEAWQGWLKHQTMLINEYRLSPIDPKSRTFLEKQMEAYFFGDGAQSPEGYVPPAPQDS",
    "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIAEAIDAGQRQFGENYVQEGVDKIRHFQELGVTGLEWHFIGPLQSNKSRLVAEHFDWCHTIDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRLRGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTMVRIGTAIFGARDYSKK",
    "output": "Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNIIDTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAAPIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSELKEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDPYVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILESMEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMVSYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLIDVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQVVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE",
    "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSCDLGGLWRFTEHVEEGRASLYNSVVSNSSKEMSCYSDFPFPEDYPNFVPNSLFLEYLQLYATQFNLLRCIYFNTKVCSITKRPDFAVSGQWEVVTVCQGKQSSDTFDAVMVCTGFLTNPHLPLDSFPGIQTFKGQYFHSRQYKHPDVFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTGGAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPVVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVLIKPSIKEVKENSVVFNNTPKEEPIDVIVFATGYSFAFPFLDESIVKVEDGQASLYKYIFPAHLPKPTLAVIGLIKPLGSMIPTGETQARWVVQVLKGATTLPPPSVMMKEVNERKKNKHSGFGLCYCKALQSDYITYIDDLLTSINAKPDLRAMLLTDPRLALSIFFGPCTPYHFRLTGPGKWEGARKAILTQWDRTVNVTKTRTVQETPSTFETLLKLFSFLALLVAVFFIFL",
    "output": "Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics . Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes (By similarity). In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLTLGLESSCDETSCSLVQNGKILANKIASQDIHASYGGVIPELASRAHLQTFPELLTAATQSAGVSLEDIELISVANTPGLIGALSIGVNFAKGLASGLKRPLIGVNHVEAHLYAACMEAPATQFPALGLAISGAHTSLFLMPDATTFLLIGKTRDDAIGETFDKVARFLGLPYPGGQKLEELAREGDADAFAFSPARVSGYDFSFSGLKTAVLYALKGNNSSAKAPFPEVSETQKRNIAASFQKAVFMTIAQKLPDIVKAFSCESLIVGGGVANNSYFRRLLNQICSLPIYFPSSQLCSDNAAMIAGLGERLFCNRTHVSKEVIPCARYQWESACS",
    "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKTFTAKPETVKRDWFVVDAAGQTLGRLATEIASRLRGKHKPEYTPHVDTGDYIVVINAEQIRVTGAKTTDKIYYSHSGFPGGIKSINFEKLIAKAPERVIETAVKGMLPKNPLGRDMYRKLKVYAGAVHPHTAQQPQELKF",
    "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKEEAIEVEGKVVEPLPNAMFRVKLDNGHTILAHISGKMRKFYIRILPGDRVTVELSPYDLTRGRITYREK",
    "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIRAAIKGSGSALPRKVVTNEELAARVDTSDEWIVERTGIRQRYIAGADEFTSTLAMEASRKALEAAGITPETIDLIVLATATPDNTFPATATKVQEALGCNGCIAFDVQAVCSGFLYALATADSLLKTGMAKRALVIGAETFSRILDWEDRTTCVLFGDGAGAVVLEAAEGDTEAPGILASRLHADGAQHDLLYVDGGPSTTQTVGHLRMRGREVFRHAVVNLADVLKEVLDDAGVSASDIDWVVPHQANARILDATARKLGLPMEKIVVTVDRHANTSAASVPLAFDTAVRDGRIKPGDLVMFEAMGGGFTWGASLVRY",
    "output": "Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNGQHSSPGTPVQRPSAGPVNQAQFSQQRTNQLTSLLHTMTMYQQLAQNVGLNTPQGQVYLLQAQTIRRQLQGHAQSGQLPNQQLLQQLQSNGALQQGTPEPSNTRPRPQLNAQEQTMLLVRHRQLQTAQNYLTEMKEALGRIKNELSTNERLDTSAREALVKQESELTVKIAQFTAAISNGIRSIQQLQNRQASSANGNNTGTSTPVNASTDTRKSTASTPQLQQTQAQANAPQQRINPETSSVPETPVGVSAANVSNESTELATSATQQSGLANNVEKSQTPSYMSANHLPKVDSKSPIPFSVPPSRATLTGGYASGSIGLSTPGLSRAPHYELDNGNRLLSKRKLHDLLQQIDSEEKIEPEVEELLLEIADEFVESVTNFACRLAKHRKSDTLDVRDVQLHLERNWNIRLPGFASDDIVKSARKTGPTPSYQQKQNAIGTAKSLNKD",
    "output": "Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation), facilitation of DNA opening and initiation of transcription. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation (gcn5) and deubiquitination (ubp8). SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation. SLIK is proposed to have partly overlapping functions with SAGA. It preferentially acetylates methylated histone H3 (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEVATDQPRWMTHHAVLNGQHPESHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANSAHARARVSYSQAHARLTGSQMCRPHLIHSPGIPWLDSSKAALSAHHHNPWTVNPFTKTPLHPSAAGAPGAISVYPGSSTSSTASVSSLTPASHSGSHLFGFPPTPPKEVSPDPNSTSAASPSSSAGARQEDKDSIKYQVSLSEGMKMESASPLRSSLTSMGAQPSTHHPIPTYPSYVPAAHDYSSSLFHPGSFLGGPASSFTPKPRSKARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGSECFEELSKCMQEKSSPFSAAALASHMAPMGHLPPFSHSGHILPTPTPIHPSSSISFGHPHPSSMVTAMG",
    "output": "Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNPLSALFGAGVATRNAMFDRSLLKQQRLRGPVVSVGNLCVGGTGKTPFTQLLGDLLMQREIDFDVLSRGYGRESTEIKIVELDGSPNEFGDEPLLLAKYFAAKKPENPPRVIVGADRYEAGRFAEQKFGPRLHLLDDGFQHRGLARDFDIVLLAPDDADQVLLPVGRLREPLTALKRAHAVVATDEVKIEAFPVMPPLVWRVERDIALPEQLSRNARVLAFCAIARPHRFFTDLRRHGLEPVAELTFRDHHRYSAADIEKIVREISSSRADCCVTTIKDMMNLGELVHRLAPIYAVRLSLKLRDADAALDEIIKIIERRQG",
    "output": "Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTQTQPVGTLRLTIDDQGPQGQSRAVEQFHQGALRVIRPHYLDDSGQVCYTIIAIGGGYLGGDVYEQQFTIKDNAKALITTQSATKIYRTPQGPATQHTEINVGENAVLEYLADQTIAYREATYHQFTKVALHPSATFVMSEQITPGWHPDGKHFAYDEMRLHTEITDSTTGRLVLLDNLLLRPDSREGSFGWTEQYTHSGQMIVMGEGVDKQLVAELNEQLAAHPDVYGAVNFLSAPGTLLRGFIARTLSNRTEELINLHEHIASLLRGRWRGQEPVNLRKY",
    "output": "Probably acts in the maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity). Required for urease expression."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFMKKSSIIVFFLTYGLFYVSSVLFPIDRTWYDALEKPSWTPPGMTIGMIWAVLFGLIALSVAIIYNNYGFKPKTFWFLFLLNYIFNQAFSYFQFSQKNLFLATVDCLLVAITTLLLIMFSSNLSKVSAWLLIPYFLWSAFATYLSWTIYSIN",
    "output": "Binds tetrapyrroles and promotes the photooxidative degradation of protoporphyrin IX . Can bind the benzodiazepine receptor agonist PK-11195 (in vitro); this interferes with photooxidative tetrapyrrole degradation . May play a role in the transmembrane transport of tetrapyrroles and similar compounds (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTTIDMNQDLGKHIHLIGIGGISMSAIAEILLNQGYRVSGSDMNDSNIINKLRAHGAEIFIGHNEDNVKDPDLVVYTAAIKEHNPERMAAKERNIPQIDRAEMLGIIMKNYKKAIAVSGSHGKTTTTSLISLIMEYSNLDPTIMVGGELDEIGGNIKIGNSEHFITEACEYVESFLKFYPFIGIILNIDEDHLDYFKDLNHIKEAFRKFINLIPQEGFLIANGDDANVQEILHSIECNLITYGLDSSNTFVARNISFTNDGYPIFTVDFKGESMGTFELNIPGKHNIYNALASIATAYLLGVEPSEIQNHIKKFRGIHRRFDILGEVKGCKIVDDYAHHPVEISATLEAAKNYPHNKIWCVFQPHTFSRTKALLEDFSRSFTNADHIIITDIYAAREQDTGEVHSEILANMIQKNNMHSQVRYMKDFEDIAAYIYDHMEPGDLVLTMGAGNVYQIGQKILQRHNE",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLMPKRVKHRKVQRGRMKGRATRGNFLAYGDFGLQATTCGWITSNQIEAARIAINRYIKRGGKLWIKIFPDKPVTEKPAETRMGSGKGSPEYWVAVVKPDRVVFELSGVTEDVAREAMRLASHKLPVRTKFVTRRDFEEMGGEK",
    "output": "Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKPTIALIGRPNVGKSTLFNRLTRTKDALVHDLPGLTRDRHYGHGKVGSKPYFVIDTGGFEPVVDSGILHEMAKQTLQAVDEADAVVFLVDGRTGLTPQDKIIADRLRQSPRPVYLAVNKGEGGDRAVLAAEFYELALGEPHVISGAHGDGVYYLIEEILENFPEPEAEEADAKHPVFAVIGRPNVGKSTLVNAILGEKRVIAFDMAGTTRDSIHIDFEREGKPFTIIDTAGVRRRGKVDEAVEKFSVIKAMQAVEAANVAVLVLDAQQDIADQDATIAGFALEAGRALVVAVNKWDGISEERREQVKRDISRKLYFLDFAKFHFISALKERGIDGLFESIQAAYNAAMIKMPTPKITRVLQTAVERQQPPRAGLVRPKMRYAHQGGMNPPVIVVHGNSLHAISDSYTRYLTQTFRKAFNLQGTPLRIQYNVSENPYENAEDKPKKKPLRRVSLSNRIEKREGRKEEKNRFKKKTKVSVKKQFSK",
    "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRRGVLPTAPPAYNDIAYSMSILPTRPSVIVNETKSDVLAVPGADVPSNSMRPVADDNIDHSSHTPSGVASAFILEAKVNVISGTKVLMKQIPIWLPLGVADQKIYSFDSTTAAIMLASYTVTHFGKISNPLVRVNRLGPGIPDHPLRLLRLGNQAFLQEFVLPPVQLPQYFTFDLTALKLITQPLPAATWTDETPAGAVNALRPGLSLHPKLRPILLPGKIGKKGHASDLTSPDKIQTIMNAIPDLKIVPIDPIKNIVGIEVPELLVQRLTGKKPQPKNGQPIIPVLLPKYVGLDPISPGDLTMVITQDCDSCHSPASHPYHMDKQDSYQ",
    "output": "Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101. The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding. May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKSVITTVISAADAAGRFPSNSDLESIQGNIQRSAARLEAAEKLAGNHEAVVKEAGDACFAKYAYLKNPGEAGENQEKINKCYRDVDHYMRLVNYDLVVGGTGPLDEWGIAGAREVYRTLNLPTSAYVASIAYTRDRLCVPRDMSAQAGVEFSAYLDYLINALS",
    "output": "Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIRQCLSRRAACPCYRIAAGGTELTGCLYPQSSRISRRGRDWSSTSRRAIDTQTSGASNGADYVPLRKQLKEQAREGRAATRKGEVSPPEHEDWELTVGIEIHAQLDTDTKLFSRASAAIDDVPNSNVALFDIALPGSQPLFQPATLIPALRAAIALNCDVQRVSRFDRKHYFYQDQPAGYQITQYYEPYAKNGSIWLGPHDGIAKEDGVGVKIGIKQIQLEQDTAKSQELPSSTYLLDFNRVSRPLIEIITLPQIHSPATAAACVRKIQTILQSVGAVTTGMEMGGLRADVNVSVRKRSEGVGDHQYHGITGLGQRTEIKNLSSFKAVENAIIAERDRQIAVLRAGGAIEGETRGWTLGSTETRKLRGKEGEVDYRYMPDPDLGPVIIGIDVFFELKAKLPVLPDALLQSLVQDPKYGLSTDDAKALIELDDGDRLDYYKDAVDILITLQKDLSDDFSGGGKVVGNWVLHELGGLLTKSNLHWDSERVPAQSLAEIINLLSRNKITGSTAKSLLAMVFDGDKRSISQIVEDENLLLQSLSREEYIALAEEVMRQNPKMVMEICEKRQLGKIGWLVGQIKQIGDRNRVEAQKAEEILRELILK",
    "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEADVIKLLAAGLAMGLGAIGPGIGVGILGFGALQAIGRNPEAKGSIFTNMILLVAFAESIAIFALVISIVLIFVA",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSCFCSVQEEFYCEVLLLDESKLILTTQQQGIKKSTRGSVVLDYVFSHVNLAETEYFGVRYCDRSHQTFWLDPSKTLAEHKDLIATGPPYTLYFGVKFYAEDPGKLKEEITRYQFFLQVKQDVLQGRLPCAFNISAQLAALAIQSELGDYDPYKHTAGYVSEYRFVPDQKEDLEDSIEQIHKTLLGQVPAEAENNYLAIAKTLEMYGVDLHPVFGEKQAEYFLGLTPVGVVVYKNKTQVGKYFWPRITKVYFKETQFELRVLGRDCNETSFFFDAASKTACKNLWKCCVEHHTFFRMPENESNSLTRKLSKFSSLGSKHRYSGKTAMQIGRESTETLPRADLQVIRTRSKTYPKRSTQPAGRNNGGQAVTKMENTSEGQPKTSALTPVKSPRVKAESASVQQEKPSAPWEEDAPQSGLYNSASERNKSPKFPKAHRRSPSGGSENEPRHRRGQTADDAQANKQHRRRSRSRGNTSSGSESENSNREHRKKRNRSRQSNEMVDSAPQWEVVLRRQKEKTPNDPNQRRSRHRSRSRSPDVQAKEQLWKHIQKELVDPSGLSEEQLKEIPYKKVETQGDPIKIRHSHSPRSFGSTGAPTARTERGLCCPKSTLALIWFLLWL",
    "output": "Not known, binds calmodulin."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGRSSKKGPYVDKKLLEKIRKLNETGEKKVIKTWSRASMIIPEMVGHTIAVYNGMKHIPVYITENMIGHRLGEFAPTRRFGGHADKKAKKGELKK",
    "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPPKKKLVKTFTLQLPAGQATPAPPVGPALGQHGVNIMEFCKSYNAQTESQRGDIVPAEISVYEDRTFTFVLKTPPAARLLIKAAGVAKGSGVPHMEKVGQVSRAQLREIAEKKMADLNANDLDQAEKIIAGTARSMGLNVVD",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLDNTRLRIAIQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYLTLRRLDFGGCRLSLATPVDEAWDGPAALDGKRIATSYPHLLKRYLDQKGVSFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMAQSKQQLIDKLLTRIQGVIQARESKYIMMHAPSERLEEVIALLPGAERPTILPLAGEQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME",
    "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTKKKAHKPGSATIALNKRARHEYFIEDEYEAGLALQGWEVKSLRAGKANIGDSYVILKDGEAFLFGANFTPMAVASTHYVCDPTRTRKLLLNQRELDTLYGRINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRTDLKDREWALDKARIMKHAGR",
    "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTVYHFVGIKGTGMSSLAQILHDMKHTVQGSDYEKRFFTQTALEKRNISILPFDKSNVKEGQVIIAGNAFPDTHEEIVAAKELNIPVHRYHHFLGDLMNQYTSVAVTGAHGKTSTTGLLAHVMQGAHPTSYLIGDGTGHGVENSKYFVFEACEYRRHFLSYNPDYAIMTNIDFDHPDYFTDINDVFSAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDGTIFDVFVRNTYYDTFKITGYGNHSVLNALAVIALCHYENVDVEAVKHQLTTFEGVKRRFNEKPMGEQVIIDDYAHHPTEINATIEAARQKHPEREIVAVFQPHTFSRTEKFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTTDVLKKHKNGVLIFMGAGDIQKFEAAYVKEVQVAEK",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKYQVVIGLEVHTQLTTNTKIFCGCSTRFGAEPNSQTCPVCLGLPGALPVLNQQVVEYAIRAGLATNCSITKRNVFARKNYFYPDLPKGYQISQFDLPICQHGHLDIEVEGEKKRIGITRIHMEEDAGKLVHADIPGVDDSCVDLNRACTPLLEIVSEPDMRSPDEAIAYLKKLHQIVMYLGICDGNLEEGSFRCDANVSLMPVGSNVFGTRAELKNINSFKFIKQAIEYEIERQAEILDDGGKVVQETRLFDPNTGTTRSMRGKEEAHDYRYFPDPDLVPVIISDDWIEKVRGGLPELPEAKRARFMSEGGAVFGGSAFGLPEYDAEVLVASRELAQYFEDTVALFPQAKTVSNWVMGEVTRALNDDNNRSIAECPVTPALLADLLKLMEKGTISGKIAKTVFDEMYKTGKASEKIVEEKGLVQVSDTGAIEAMVDEVLEKNPGQVAEYRGGKETLFGFFVGQVMRASKGKANPAVVNELLLKKLNS",
    "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRAGGDAPDQTTTIVRANSTLPAAEPLKMSHVESLLSSNQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRSSFGGAKNTNITGVIINKLNAPVDEQGRTRPDLSEIFDDSSKAQVIKIDPAKLQESSPLPVLGAVPWSFDLIATRAIDMARHLNATIINEGDIKTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYVNAEWIESLTATSERSRRLSPPAFRYQLTELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPDEINRVAASQGVELGAGIEIVDPEVVRESYVARLVELRKSKGMTEPVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQLAEIAIQSADSAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQASQQQQ",
    "output": "Involved in acetate metabolism. Catalyzes the reversible interconversion of acetyl-CoA and acetyl phosphate. The direction of the overall reaction changes depending on growth conditions. Required for acetate recapture but not for acetate excretion when this organism is grown on ethanolamine (EA); is unable to complement an eutD deletion during growth on EA . Works with proprionate kinase PduW to capture exogenous propionate and regenerate propionyl-CoA during degradation of propionate and 1,2-propanediol (1,2-PD) ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRWLPGLLLIASIGFHQSLADRVLVLGETAAVKDTHSVFLNSVKERGHELTVRAADDSQLALFKHGQLIFDHLFILAPGVQVFGGSLSPSEISKFVDAGGNVLVAAGSNIGDALREIAAEHGFEFEEAGTSVIDHHNYDQTLDSGDHTTLVVGKDQLISAELIVGNSAKLHPVLFKGIGLVAGKTNNLALSIVRASGTAYSYDPKAVRATNPSIAGSRTLLVGGLQSRNNARIVFTGSSELFSNTFFSAKTNSVNPSVQGAQSGNADFATAITRWVMKESGVLRVKTVNHHKKGETVPPVEGYFITEDVVYTIEIEELKNGKWVPFQGKDVQLEFVRIDPFVRATLKNSNGRLSVAFKLPDVLGVFKFLVDYRRVGYTHLYDVQQVSVRPLWHTQYERFIRSAYPYYASSFSMMAGLVLFSIVYLYHKDTPVKGAKVLDSEKKKN",
    "output": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity). Required for normal lifespan ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKALIVDDEPLARNELQYLLNLNDAIDEIEEAENIEETLEKLLYNTFDLIFLDINLMDESGIDLAQKINKMKRSPHIIFATAHEKFAVKAFELNATDYILKPFEKERINQAVNKVDMAKDKPKNKDKTITPKYIDYSDDERAQTHVLPIEVDERIHILNFTDIIALSVNNGITTIDTTKQSYETTETLNHYEKKLPSSLFIKIHRATIVNKEHIQTIEHWFNYTYQLTLTHEFKYQVSRSYMKTFKQQLGLQ",
    "output": "Member of the two-component regulatory system LytR/LytS that probably regulates genes involved in cell wall metabolism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEILEAFKVFDKDGNGFISAAELRHIMTNLGEKLTDEEVDEMIREADIDGDGQINYEEFVKMMMSK",
    "output": "Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAETPRLLFVHAHPDDESLGTGATIAHYTAAGADVRVVTCTLGEEGEVIGERWAELAVDRADQLGGYRIGELTAALRELGVGEPCYLGGAGRWRDSGMPGTPKRRRQRFIDADEREAVGALVAVIREQRPHVVVGYDPAGGYGHPDHVHVHTVTTAAVAAAGAGDFPGEPWAVPKFYWSVFATRPFEAAVQALTPEDLRPDWSMPSAEQFTFGYADDHIDAVVAAGPHAWAAKRAALAAHATQVVVGPTGRACALSNNVALPILDEEHYVLVAGAAGARDERGWETDLLAGLEFGAAPRR",
    "output": "Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGPKLFKPSIDWSRAFPDSVYWVGKAWTISAICVLAILVLLRYLTPWGRQFWRITRAYFVGPNSVRVWLMLGVLLLSVVLAVRLNVLFSYQGNDMYTALQKAFEGIASGDGTVKRSGVRGFWMSIGVFSVMAVLHVTRVMADIYLTQRFIIAWRVWLTHHLTQDWLDGRAYYRDLFIDETIDNPDQRIQQDVDIFTAGAGGTPNAPSNGTASTLLFGAVQSIISVISFTAILWNLSGTLNIFGVSIPRAMFWTVLVYVFVATVISFIIGRPLIWLSFRNEKLNAAFRYALVRLRDAAEAVGFYRGERVEGTQLQRRFTPVIDNYRRYVRRSIAFNGWNLSVSQTIVPLPWVIQAPRLFAGQIDFGDVGQTATSFGNIHDSLSFFRNNYDAFASFRAAIIRLHGLVDANEKGRALPAVLTRPSDDESVELNDIEVRTPAGDRLIDPLDVRLDRGGSLVITGRSGAGKTTLLRSLAELWPYASGTLHRPGGENETMFLSQLPYVPLGTLRDVVCYPNSAAAIPDATLRDTLTKVALAPLCDRLDEERDWAKVLSPGEQQRVAFARILLTKPKAVFLDESTSALDTGLEFALYQLLRSELPDCIVISVSHRPALERLHENQLELLGGGQWRLAPVEAAPAEV",
    "output": "Multi-solute ABC transporter that mediates uptake of unrelated hydrophilic compounds . Can transport vitamin B12 and related corrinoids, and antimicrobial peptides such as bleomycin . Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation . Contributes to maintenance of chronic infections ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRIEEGLKLGFKDVLIRPKRSTLKSRSEVALERQFTFKHSGWNWSGVPIIAANMDTVGTFRMAEVLASFDILTAVHKHYTLEQWAEFVKRSPESVLRHVMVSTGTSSADFDKMKQILALSPSLKFICIDVANGYSEHFVSFLQRAREACPDKVICAGNVVTGEMVEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGQIVSDGGCSVPGDVAKAFGGGADFVMLGGMLAGHDECEGRVVEENGEKFMLFYGMSSESAMKRHVGGVAQYRAAEGKTVKLPLRGSVDNTVRDIMGGLRSACTYVGASHLKELTKRTTFIRVAEQENRVFGTD",
    "output": "Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSTIPVTIDFSGGAEFLVKAKAQKVQIPADSTLRDVLKFVRDNLVTDVHRINMLLNDDASEVAHGVITLINDTDTGLLLEYDTVIEAGDTITFVSTLHGG",
    "output": "Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPTQSVDSVKAVRVRPFSQREKNSGSKCVISMHSRTTTTTQDPKNPEHVKTFTFDLAYWSHNGFQRDKDGVLISADPSRKFAGQRDVFHDLGRGILDSAWQGYNATLLAYGQTGSGKSYSMIGFGCKQGIIPTVCEELFRAIENQGRNQEHQVMFSMLEIYKEIIRDLLSRTKKPGGLRIREDQQLGFYVEGLKSVPCENYAQIERLMEQGTKIRTTASTNMNASSSRSHLVITIQFKQVFLDRDLTKQSSINLVDLARSERQKSSGSEGDRLREGSCVNLSLTNLGSVISVLADAAMGKKVLHIPYRDSVLTKLLQSALGGNSRTALVAAVSPADICYEETLSTLRYAERERKIRNRAVANTWTLMRKSRAENSKLLPMMTFPHLLNLSEDPQLTRVLKYFIQAGTQPAPCPRPALSPPHPALRISDKHASFTNADGKVTVTPHSKCKVAVNGVPITTRTKLQHLDRLILGSNSTYLYVGFPSEWGSEDLSRFDYDFFQLERAAAEGASADKLGAADGGDGKAGPSVLAAFQDYIKLMPLVSEANQMSEEPKKGLNMELKVKNLASSDSRGYDLQKEVLVKVTHHGSHEVWIWSKAKFINRKFLMQELYQRFLDGDHGPVARDDDPFWDPVEVVRLGSAHIWLQSLAYCMKLEEQVEFLNCDGLEEAVLHTCIAPCSPTGQTHGEEDVVIDPLELLGKRMDFQIHIVRCLGVNWMKEDAKRGTQIGYRIYDLPNTIYTKPVWKSVNPQIEETVQFAALTASQEFLNYLRTNALIVDLWGLQEGCTELSCSQLGLMVTGEGHILVDTKKISTVKDISQAASNQIPELYLKLLKLEQETEPLRNINRALREENVLLKASLAKTASGQAPKPSNTLKISGMTAQLPSAGEMSQMCTQQAGSDRELAKALKVFYQSMNTARGQLFRLRRHQPPEVDQMLRPFIHQRSQMFKDLGDLRESSLWTLKMTLLL",
    "output": "Microtubule-dependent motor protein required for mitochondrion morphology and transport of mitochondria in neuronal cells."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAQTIDIANPTRTQAILNEYGLRAKKKFGQNFLTDLNVLHNIVEAAEITAEDYVIEIGPGIGALTEQLARSAKKVLAFEIDSQMVEVLADTLKPYDNVKVIENDVLKVDLAKVISEEFGDNAHVKIVANLPYYITTPILIQLLRSNINWDNIVVMMQREVADRLNAAVGTKSYGVLTLTIQYFAQATLAIKVPASSFNPSPNVDSAVVKLTPLKPTTVVENVGKLFGVIKGSFSHRRKSLWNNMLQTYGKDAGTKEQLTVALKSAQIDPAIRAERLNLEQFTQLYLALRDQNLTQ",
    "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTAAITYEHIKTCKQSGARLGRVHTPHGTIETPMFMPVGTLATVKTMSPEDLKAMDAQIILSNTYHLWLRPGEEIIKEAGGLHQFMNWDKPILTDSGGFQVFSLSDLRKITEEGVHFRNHLSGEKLFLSPEKAMQIQHVLGSDIMMAFDECPPYPADHSYMKASVERTSRWAERCLAEHKRSGKDSVQGLFGIIQGGEYEDLRKQSANDLTALDFPGYAVGGLSVGEPKDVMNHVLEFTTPLMPEDKPRYLMGVGSPDSLIDGAIRGIDMFDCVLPTRIARNGTCMTSAGRLVVRNAKYARDFSPLDEKCDCHVCRTYSRAYIRHLIKCEETFGFRLTTYHNLYFLLNLMKQVRQAIMDDCLLDFREQFFEEYGFNKENARNF",
    "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER",
    "output": "Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTIIFVDNEEYNVDKSDNLLQACLSSGINIPYFCWHPVLGSIGSCRQCAVTIYKDLEDKVGQLVMSCMTSVLDGMIVSTSDKISRNFRKGIIELLMLNHPHDCPICEEGGSCHLQDMTVMAGHTVRRYRFTKRTHKNQYLGHFITHEMNRCISCYRCVRYYKDYSGGTDLGVFGISNNVYFGRYNDGCLESEFSGNLVEVCPTGVFTDKTYSKKYSRKWDMQYAPSICQHCCVGCNISVGEKYGKISRIENRYHNAINHYFLCDLGRFSYDYSNVDERLTYSIYRSQNKTKIINDVNKTIDKLAMKFKKSSKIIGIGSCRASVESNFSLQKLVGSENFYLGISQKEYDCLMLIKDILKDNQIHVPTLREIEKSDVIFLLGEDVTKTSPLIALSIRQSIKGQVKTQDVSKNIPIWHADAVKNSFRNNKNKLFITNLMNSSLDDIADESYYASTFDQVLLGAEVYKCISNNCISNVTLLKQDLLSCAKRIATALTLSKCPLIISGSHSYNLDLIKVSFNIAKSLKVIGKNVGLILLSSNVNSIGVSLLEGISIEKVINKVLLKQIDKIIVLENDLYRYLPESIVDTLFKSSSCTVVIDHLNTRTLKQADIAIPTCNSFESSGTVVNYEGRAQRFFKTYHPNSSENKKSILESWKWLHLLYCKLHKISVFWHSLDDVIEEISLKIFSFSKLKDVAPNSSFKIFGQKLARSHHRASGRTALYSNINIHEPRPPQDNDTMFSFSMEGCQNVQNYLPYVPFSWFPGWNSVQSWNTYKKINNENYGKHLFQDTTKFVLTYYKLNCKNVNKIEDLYLIVPCYFLFCNNELAQYSPVIQENVLKNAYGIINTEDAKVLLIESGSKIEFSYLNKNFSIKVQLSKEFKKGQLGLPLGMADFPFFLAEKQVKVFRKISI",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS",
    "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATRLANVPQREAGTILERKEQALKPPAMFKVVLLNDDYTPMEFVVMILQQYFSRDRETATQIMLTVHREGKGVCGIYTRDIAATKVELVSTHARQAGHPLQCVMEEA",
    "output": "Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIELGVNIDHVATLRQARRTWEPDPAWAAMEAHLGGADGITVHLREDRRHIQDEDVRRLRELTQVKLNLEMAATDEMVGIACALRPEMAMLVPEGRHEVTTEGGLDVLAQEGRLKDVVARLADAGIVTSVFIDAELGQVEAAARIGARVCEIHTGPYAHAFHAAGRDPQSAAVVDEIDKVRRAGEAIRALGMRFNAGHALNYYNVQPIARLPEVRELHIGHAIVSRSVFTGLRDAVREMKRLMREAAGVGR",
    "output": "Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MINKNEWLTVGLITSCHGINGQVKVKSLSDFEERFLKPGMRWLQKENEPPSKIELISGFKQPGKETFIVKLQGINTRNDAEQLKTFKILVRTDKLPKLKKEEFHLLELINLEVKTLENDELKTIGKVINLENEKNNLLIIELFKNQKKVLIPFVKEIVPLVDIKNQFVIINPPNGLLEL",
    "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRRIQSIARSPIAIALFMSLAVAGCASKKNLPNNAGDLGLGAGAATPGSSQDFTVNVGDRIFFDLDSSLIRADAQQTLSKQAQWLQRYPQYSITIEGHADERGTREYNLALGQRRAAATRDFLASRGVPTNRMRTISYGNERPVAVCDADTCWSQNRRAVTVLNGAGR",
    "output": "Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQVTQTLNEGLKRGYTITLTGAELDAKVTEKLIEVQPEVEIKGFRKGKVPMAMLRKNFGDRVLGDVLNESVDGAIKDLLDQSGDRPALQPKVEMENGKDWKPGTDAIFTVSYEALPPIPAFDRATVTLERLVVKADEASVTEALENLAKSAQAFEDRKKGTKAKDGDQVVIDFEGFLGDEPFEGGKGEEYPLVLGSNSFIPGFEDQLVGAKAGEDVEVKVTFPAEYGAAHLAGKEATFKCHVHAVKAPKPAEIDDELAKKFGAADLEALKGQVASRLEAEYKGASRAILKRALLDILDAQVKFDLPPSLVEAEAGQIAHQLWHEENPDHHGHDHGAVEPTEEHKTLAERRVRLGLLLAELGRNEKIEVTDAEMTQAVLAAARQYPGHEREFFEFVKGNAQMQQQIRAPLYEEKVIDFIVAGAAVTEKEVSKEELQKAIEALDEL",
    "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MILHAQAKHGKPGLPWLVFLHGFSGDCLEWQEVGEAFADYSRLYVDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILSFWLVGYSLGGRVAMMAACQGLAGLCGVVVEGGHPGLQNAEQRAERQRSDRQWAQRFRSEPLTAVFADWYQQPVFASLNDDQRRELVVLRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIASLAQILRF",
    "output": "Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSGAAFSRQRGQLLSDTLAAAKAEGRSALIAYLPAGFPTVDGGIAAIKAVFDGGADVVEVGLPHSDPVLDGPVIQTADDIALRGGVRIADVMRTVREAHEATGKPVLVMTYWNPIDRYGVERFTAELAEAGGAGCILPDLPVQESALWREHAEKHGLATVFVVAPSSKDARLAEITAAGSGFVYAASLMGVTGTRASVGEQAQDLVRRTRATTDLPVCVGLGVSNATQAAEVAGFADGVIVGSAFVKLMLDAEDEAAGLEAVRALAGELAKGVRGGD",
    "output": "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTKITVNYTVDVKDIQPKHVRSESNPQNQNKIRRAWVLSLSDNAMEVIQNKIKSAPARHAYYEAIDREVSNKWIELMRKHTTESLNAGAKFIMTSCGERLEDDYCGNADERLIVAAQIVAETIAADFNR",
    "output": "Binds to host RNA polymerase core."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAQTMLLTANAKVDLRSKESLVERLKPKPLSSLFLPSLPLRFSSSSTNASSSKFTSTTVALFKSKAKAPPKKVAPPKEKQKVEDGIFGTSGGIGFTKQNELFVGRVAMIGFAASLLGEAITGKGILAQLNLETGIPIYEAEPLLLFFILFNLLGAIGALGDRGKFVDDPTPPTGLEKAVIPPGKSFKSALGLSEGGPLFGFTKANELFVGRLAQLGIAFSIIGEIITGKGALAQLNFETGVPINEIEPLLLFNIAFFFFAAINPGTGKFITDEEED",
    "output": "Seems to be involved in non-photochemical quenching, a process maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MHLNIILLEASLELVPKEIVNHPAVIKNAKRRNKKPEDTLLDISLHYHAMKYLENSHKRGRPDILHQALLVILTDPVIKGDIFIHTIQSKIIKVNPNMRPPKNYLRFIGLMEQLLKYGKIPINGDETLMEVTNLTLDNIVNRYDLILLSEKGEKINPEEICKLDEKWLLGIGAFPHGDFSDKILNLAKKIYSISGFPLETQQVLCRIFSACNSILGWP",
    "output": "Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLTITSYFGFLLAALTITPALFIGLNKIRLI",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSSSSSRIHNGEDVYEKAEEYWSRASQDVNGMLGGFEALHAPDISASKRFIEGLKKKNLFGYFDYALDCGAGIGRVTKHLLMPFFSKVDMEDVVEELITKSDQYIGKHPRIGDKFVEGLQTFAPPERRYDLIWIQWVSGHLVDEDLVDFFKRCAKGLKPGGCIVLKDNVTNHEKRLFDDDDHSWTRTEPELLKAFADSQLDMVSKALQTGFPKEIYPVKMYALKPQHTGFTNN",
    "output": "Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNFDSIIKNGLVILENGEQEVEVGIKDGKIAAIGQDLGTSAKIIDAKGSIVSPGMIDAHVHITEPGGGYRDEWEGYDTGTRAAAKGGVTTFIEMPLNQVPATVDEESIQEKFKAGKGKLSVDVASYGGLVPFDLDGGIQELDSNGVVAYKCFLATCGDRSIEGDFMNVDDYSLYEGMKQIAKTGKILSIHAENAAITDKLGEIASKNGETSLRAYVDSRPVFTEVEPIRKIILFAKETGCRVHIVHIACEEGVDEIVKAQQEGVDITCETCTHYLYFYKEELDHIGPVVKCSPPIREQSRLEGMWNRVLNGDISFVTSDHSPCTPDLKATDNAFEAWGGIAGLQNNVDVLFDEGVQKRNMPLSKFAAIIATNPAKRFNLASKGSIAVGKDADFVFIKKDAPYELKAEDLAYRHKISPYIGRKIGAQVVKTILRGVEIYDKEKGISNEKVGRFIP",
    "output": "Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MISSLRGTVLSVSGQTLLLEVHGVGYGVSVTPRHALELRHGSEATVLTSLVVREDSLTLFGFPGPDELRAFELLCGVTGVGPKSALAVLEHLDPEAMAQAVAAEDDAAFRRVSGIGPKTAKLIVLQLAGKLFVTQPRTRSASSAASTVTADVVTALIGLGWSERVARTAVDDAAAAAAEQGLPADMPRLLRVALGMLGPQQPAGAPAAAQAADR",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKRLALALKQRKVASWKLEEVKELTELIKNSNTILIGNLEGFPADKLHEIRKKLRGKATIKVTKNTLFKIAAKNAGIDIEKLEQYLTGPNVFIFTKDNPFITNMFFENYKLRRYAMPGDKAEEEVVIPAGDTGMPAGPILSVFGKLKVQTKVQDGKVHVVKDTVVAKPGDVIPAEALPILQKLGIMPVYVKLKIKVAYHEGLVIPAESLKLDLEGYRSNITEAYRNAFTLAVEIAYPTPDVLKFTISKVFKNAIALASEIGYITPESAQAVISKAVAKAYALATAIGGKVDLGVQLPTVQQSQSQQPAAEEKKEEKKEEEKKGPSEEEIASGLASLFG",
    "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRICFLLLAFLVAETFANELTRCCAGGTRHFKNSNTCSSIKSEGTSMTCQRAASICCLRSLLDNACDSGTDIAKEEESCPSNINILGGGLKKECCDCCLLAKDLLNRNEPCVAPVGFSAGCLRSFNKCCNGDIEITHASEIITGRPLNDPHVLHLGDRCASSHCEHLCHDRGGEKVECSCRSGFDLAPDGMACVDRNECLTRQSPCTQSEDCVNTIGGYICQRRISRLVPHRHRANRIGNAPRRMRDDPYSRAGEYREASQANTEFGCPMGWLFQHGHCVDVDECNLGSHDCGPLYQCRNTQGSYRCDAKKCGDGELQNPMTGECTSITCPNGYYPKNGMCNDIDECVTGHNCGAGEECVNTPGSFRCQQKGNLCAHGYEVNGATGFCEDVNECQQGVCGSMECINLPGTYKCKCGPGYEFNDAKKRCEDVDECIKFAGHVCDLSAECINTIGSFECKCKPGFQLASDGRRCEDVNECTTGIAACEQKCVNIPGSYQCICDRGFALGPDGTKCEDIDECSIWAGSGNDLCMGGCINTKGSYLCQCPPGYKIQPDGRTCVDVDECAMGECAGSDKVCVNTLGSFKCHSIDCPTNYIHDSLNKNQIADGYSCIKVCSTEDTECLGNHTREVLYQFRAVPSLKTIISPIEVSRIVTHMGVPFSVDYNLDYVGQRHFRIVQERNIGIVQLVKPISGPTVETIKVNIHTKSRTGVILAFNEAIIEISVSKYPF",
    "output": "Incorporated into fibronectin-containing matrix fibers. Plays a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Important for certain developmental processes and contributes to the supramolecular organization of ECM architecture, in particular to those of basement membranes.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDPNCSCSTGGSCTCSSSCGCKNCKCTSCKKSCCSCCPVGCSKCAQGCVCKGASDKCTCCA",
    "output": "Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKFYKYCASGNDFVIFADSEKKDRSELAKILCNRYEGIGADGLIVIVPHDRYDFEWEFYNCDGSKANMCGNGSRAAAHFAHHHLKKSQYLNFLTGAGLIKSFVDDDIVEIKLSGIKDIKEAFEYKDRIWQGCNTGVPHIVTFVDDLSEFDINLCKEVRKKYNANVNFAKVEDDEFIRVRTYERGVEDETLACGTGMGACFYLAYLNQKVKDDILIKPKSNESLYFRLEEEQIFFRGKVKCCFEADYNFT",
    "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDIVGGQNLRQMWDDLAGVYGDKTALIFESCEGIVRQFSYASLNEEINRTANLFYSLGIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESAWILQNSQVSLLVTSVQFYPMYREIRQDNSTPLNHICLIGEQLPADDGVSHFSQLQARQSATLCYTPALSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQIALRDDDVYMTVMPAFHIDCQCTAAMPAFSAGSTFVLLEKYSARAFWDQVRRYQATVTECIPMMIRTLMVQPAAPTDRQHHLREVMFYLNLSAQEKDAFTERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATAGALEPEGWLHTGDSGYQDEDGYFYFVDRRCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIKDAIRDEAIKAFIVLNEGETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCSGKIIKKNLK",
    "output": "Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "METLSARFTVLQEKLMDIYESGVEDLDTQIQHWQLLRQEQIIYHYARRHGVTRLGYQPVPSLASSEAKAKDAISMVLLLESLKKSKYADEQWTLAQTSLEAVRSPPADCFKKGPKNIEVVFDGDPENLMSYTVWTYIYYLTDEDIWEKVEGHVDYTGAYYYEGKLKVYYLKFENDAKRYGVTGLWEVHVNKDTVFTPVTSSTPPVGDSTDSASRAALPEPSTSVSPERPPSQTARRYGRKASSPSTTSRRQRKGQRETTGTQRRRKSRSRSRSTNRGGRDTRRSSSRGSSVSPTRGRRRGGGDSRRRGPVTRSRSRSLSRASSAGGGISPDKVGTAVRSVGRQSGGRLTRLLADAADPPVILLRGDANTLKCYRYRFRKKHAGGFRFVSTTWSWIGDASNDRIGRSRMLLAFYSESQREKFIQTMKLPTGVEWSLGQFDDL",
    "output": "Plays a role in the initiation of viral DNA replication. A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity. Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA. E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome. Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box. Repression occurs by sterically hindering the assembly of the transcription initiation complex."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MANIKSAIKRAKTSEK",
    "output": "Binds directly to 16S ribosomal RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLKIGIVGGTGYTGVELLRILSQHPEVNIEAITSRKEAGMDVAQLFPSLRGRIELKFSDPAEANLEKCDVVFFATPNGIAMKQVPSLLDAGVRIIDLAADFRIKDIAVWEKWYGMPHACPELVAEAVYGLPEINRDRIKTARLIANPGCYPTAVQLGFLPLVESGAADLDHLVADAKSGVSGAGRNAEIHTLFAEAADNFKAYGVSGHRHLPEIRQGLSQAAKHPVGLTFVPHLTPMIRGIHATLYVKLLKEVDLQALYENRYVNEPFVDVLPAGSHPETRSVRGSNLCRIAVHRPQGGDTAVILSVTDNLVKGAAGQAVQNMNLMFGLPETLAITHLPLFP",
    "output": "Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSLANHTFSNPSRVLQRNESLFTNKNILVAGNIDDEYPLQLQALANSSTFCFSDYRYYSVLKDKLTTSEVHFTDNYQGETKFDLLLIFLPKAKQETLYLLANLTPHLQPGASIILVGEKKCGIKSADSLLASYSNRINMIDSARHCSILHAELNQPVNAFTQSQWIKTYPLNINNTELQICSLPGVFSYGELDKGSELLLQNLPDKMSGRVLDFGCGAGVIACYVLKKHPQLSVDLVDINAFALASAKLSLQSNQLEGNVFPSNVFSDIKEKYNILLSNPPFHSGKNTDYTAAETFINQSTNHLKSKGKLSIVANRFLNYEGLLFKAFSNVKIDQESNKFKVLSCITKT",
    "output": "Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSNRKYFGTDGIRGRVGNAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSASFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKEITCVDSAELGKASRIVDAAGRYIEFCKGTFPNELSLNGLKVVVDCANGATYHIAPNVLRELGATVIAIGCEPNGVNINEEVGATDVRALQARVLAEKADLGIALDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKLQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMVRNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLENEAVKAVTADVEATLGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTAFAHRIADAVKAV",
    "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRLVLLGPPGSGKGTQAAQMKETLQIPHISTGDLLRSEVVAGTPLGLQAKQVMAQGDLVSDAILIGMLESRLSHTDVVKGFILDGYPRNLSQAAALDGLLAKLGHPLNAVVQLEVPTDVLVERIAGRAQAEGREDDTPDAVRKRLQVYNDSTAPVIGFYQQRGILLRVDGVGRLDEVSQRIVVALGC",
    "output": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSYRPYQQIERRKSRQIHVGKVAVGGDAPISVQTMTNTLTTDAEATIAQIRRAELAGVDIVRVSCPDQESTIALKEIVREVNVPIVADIHFHYRRAIEAAEAGAACLRINPGNIGSAERVREVVKAARDHGCAIRIGVNAGSLERHLLEKYGEPNPDALVESALEHAKILQDHDFHEFKISVKASDVFLAVAAYQQLAEVCDHPLHIGITEAGGRRTGTVKSAIGLGNLLWAGVGDTMRVSLSAEPEEEVHVGWEILKGLGLRHRGVKIISCPSCARQGFNVIETVAALEERLAHIQTPLTLSIIGCVVNGPGEALMTDIGLTGGGGGRHMIYNAGKTDHTIAADGMVDHIVTLVEEKAARIVEEEAAAKAAAEQAAQEAALQHETV",
    "output": "Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPRSLKKGPFVDHHLLKKVFEAQESNSKKPIKTWSRRSMIVPDMIGLTIAVHNGQQHVPVLMTEEMVGHKLGEFVVTRNYRGHAADKKAKKK",
    "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQLTELIETTVTGLGYELVDLERTGRGMLCIYIDQPAGISLDDCEKVTRQLQHVLTVENIDYERLEVSSPGLDRPLKKLADFERFAGSEVSVTLKKPLDGRKTYRGILHAPNGETIGLEFERNKGEAAMLDFTLADIDKARLIPQVDFRSRK",
    "output": "Required for maturation of 30S ribosomal subunits."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS",
    "output": "Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSDDRINYLKNKLVQYPDFPKKGILFEDIMPIFQDPRAFGILIDLLLEAVETEFNNIDVIVGLEARGFLFGPTLALRANCAFVPVRKPNKLPGDLVVVSYNKEYSTDSFAIQKGTIKPGQRVLIVDDILATGGTALAADELVTRLGGELVGHLFLLELTFLQGRKRLMAPTYTLLTGQDEAPDGSEFA",
    "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLVLAPKNDK",
    "output": "IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEEFQGYLELDRSQQHDFLYPLIFREYIYALAHDHGLNRSILLDNVGYDNKSSLLIIKRLISRMYQQNHLIISANDSNPPQNWGYNKNLYCQMISEGFAVIVEIPFSLRLVSSLEGTETVKSYNLRSIHSIFPFLEDKFPHLNYGSDVLIPYPIHLEILVQTLRYWAKDPSSLHLLRLFLHDYYNLNSLITPNKSIFSKSNPRLFLLLYNSYVCEYESILLFLRNQSSHLQFTSSWIFFERIHFYEKIKYPVEEVFANDFPAILWFFKDPFMHYVRYQGKSILASKDTPLLMNKWKYYLVNLWQCHFYVWSQPGRIDINQLSKHSLDFLGYLSSIRPNLSVVRSQMLENSFIMDNAMKKFDTLVPIIPLIGSLAKVKFCNALGHPISKSTWADSSDFDIIDRFVRICRNLSHYYSGSSKKKSLYQIKYILRLSCVKTLARKHKSTVRTFLKRLGSKLLEEFFTEEEQILSLIFPRASSTLKRFYRERIWYLDIFCINDLVNHE",
    "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "NTGAKAPRKHLANKAARKTAAPANAGIKKPHRYRPGTVALREIRKYQKSTDLLIRKLPFQRLVREIASEYKNDLRFQSSAVLALQEAAEAYMIGLFEDTNLCAIHGKRVTIMP",
    "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNREGAPGKSPEEMYIQQKVRVLLMLRKMGSNLTASEEEFLRTYAGVVNSQLSQLPPHSIDQGAEDVVMAFSRSETEDRRQ",
    "output": "Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVFGTGVDNVELSRIQKALTRSERFVEQVLTAVELEKYNSFQSTARKTEFLAGRWAAKEAFSKAYGTGFGKALGMHDLEIKNDELGKPFFTKHPFDGQVHLSISHSNLEAVAFVVLEKN",
    "output": "Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MHFEVHGRTDAEAPTILLSSGLGGSSAYWLPQIEALSDHFRIVTYDHRGTGRTGGEVPTEGGISAMADDVLEIVSALNLEKFHFMGHALGGLIGLDIALRQPRLIDRLVLINAWSKADPHSGRCFDVRIELLEKSGVDAFVKAQPLFLYPAAWMSEHQERLARDDAHGVAHFQGKTNVLRRIAALRAFDIDARLGEIGNPVLVVATKDDLLVPYTRSLRLAEGLPQSELCLLDFGAHAVNITEPDLFNTRLLQFLLPADQT",
    "output": "Involved in pyrimidine catabolism. May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFVIPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLPVHAPTSGTVTAIAPHSTAHPSALAELSVIIDADGEDCWIPRDGWADYRTRSREELIERIHQFGVAGLGGAGFPTGVKLQGGGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKPQAISMLRAVLADSNDISLRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNVGTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQMVIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLLPQQLYWFSKGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEEKRAAEAKARFEARQARLEREKAARLERHKSAAVQPAAKDKDAIAAALARVKEKQAQATQPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVADPRKTAVEAAIARAKARKLEQQQANAEPEEQVDPRKAAVEAAIARAKARKLEQQQSNAEPEEQVDPRKAAVEAAIARAKARKLEQQQANAEPEEQVDPRKAAVEAAIARAKARKLEQQQTNAEPEEQVDPRKAAVAAAIARAQAKKAAQQKVVNED",
    "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNTVRVTFLLVFVLAVSLRQADKDENRMEMQEKTEQGKSYLDFAENLLLQKLEELEAKLLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK",
    "output": "Probable ion channel inhibitor."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPTINQLVRKPRKSKVEKSDSPALNIGYNSHKKVHTKLAAPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVTDRKQGRSKYGTKKPKA",
    "output": "With S4 and S5 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFAEGRIPLWLVGLIAGIGAISVLGLFFYGAYAGIGSSM",
    "output": "One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGEVQREKVAVIIGPTAVGKTKLSIDLAKALNGEIISGDSMQIYRTMDIGTAKVTKEEMDGIPHYMVDIKNPEESFSVAEFQERVRKHIREITERGKLPIIVGGTGLYIQSVLFDYQFTDDAGDVIYREHMEKLALERGVEYVHKKLQEVDPESAERIHANNVRRVIRALEIFHTTGEKMSDQLEKQENELLYDVSLIGLTMDREMLYDRINLRVDIMMDQGLLEEVEGLYNRGIRDCQSIQAIGYKEIYDYFEDRVSLEEAVSQLKTNSRRYAKRQLTWFRNKMDVTWFDVTDGEKTSEILRYIEGKLQLKSNNSK",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQVTPTGPTETSLISVLADATATYYNSYSVS",
    "output": "Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'-AACAAT-3'."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRTVIQRVKYAKVSVDGKILGEINKGLLVLLGITHEDSIKEVKWLVNKTKNLRIFEDEEEKMNLSLEDVKGKALIISQFTLYGNSIKGNRPSFIDAAKPDLAKDLYLKFIEELKSFDIETQEGEFGADMKVELLNDGPVTIIIDTKDANIK",
    "output": "An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAGHEVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDAGLKEVFEDVLPISNFTDTMDLEFVGYELKEPKYTLEEARIHDASYSAPIFVTFRLVNKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELETDAKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGDSELVRNTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLVARFFDPRRYDLAAVGRYKINKKLNLKTRLLNQTIAENLVDGETGEILVEAGTVMTRDVIDSIAEHIDGDLNKFVYTPNDYAVVTEPVILQKFKVVAPTDPDRVVTIVGNSNPEDKVRALTPADILAEMSYFLNLAEGIGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRSTGAVTNEIVWLTADEEDEFTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFPSSIVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAKHDGRVIFSDAEKVEVRREDGSLDVYHVQKFRRSNSGTAYNQRTLVKVGDLVEKGDFIADGPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKLGPEEITREIPNVGEDSLRDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGGDGVVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGASSEDLWETVQEAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVELRDLDEGEDDDVMHVDDLEKARVKQEAEEKQAEQVSEVVQED",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSADGRSGRLRFTKMHGAGNDFVVLDLRDGTPPPDAALAAQLADRHFGIGCDQILTIEAPRSEGAAAAYGIWNSDGSAARQCGNGARCVAAWLVRDGTAQGERFIIDSPATAHAVERLDGDRYAVAMGVPQFEPTQIPLAGFAHARDEYALPVHGETVRFGAVSMGNPHAVVEVGRVDAAPVERVGALLQQNAAFPDSVNVGFAQVVDPVHVRLRVFERGVGETLACGSGACAAAAVLMQRGRVERDVQVSLPGGELRIRWPGDQEQVVMSGPAVFVFDGEWNR",
    "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNKDSTQTWGLKRDITPCFGARLVQEGHRLHFLADRAGFTGSFSEVQTLQLDEAFPHFVAHLELMLLSCELNPRYAHCVTLYRNGLTGEADTLGSHGYVYIAILNRHGFNRHLRVI",
    "output": "Putative antitoxin component of a type IV toxin-antitoxin (TA) system; its cognate toxin is unknown."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPAHLLQEEISSSYTTTTTITAPPSRVLQNGGGKLEKTPLYLEEDIRPEMRDDIYDPNYQDKEGPKPKLEYVWRNIILMGLLHLGALYGITLIPTCKIYTFLWVLFYYVISALGITAGVHRLWSHRTYKARLPLRVFLIIANTMAFQNDVFEWSRDHRAHHKFSETDADPHNSRRGFFFSHVGWLLVRKHPAVREKGATLDLSDLRAEKLVMFQRRYYKPGVLLLCFILPTLVPWYLWGESFQNSLFFATFLRYAVVLNATWLVNSAAHMYGYRPYDKTINPRENILVSLGAVGEGFHNYHHTFPYDYSASEYRWHINFTTFFIDCMAAIGLAYDRKKVSKAAVLGRMKRTGEESYKSG",
    "output": "Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAAVSEVEVDGVVFPPVARPPGSGHAHFLAGAGVRGVEIAGNFIKFTAIGVYLEEGAAVPALAKKWAGKSADELAADAAFFRDVVTGDFEKFTRVTMILPLTGEQYSDKVTENCVAAWKAAGVYTDAEGAAADKFKEAFKPHSFPPGASILFTHSPPGVLTVAFSKDSSVPEGAVAAAAIENRALCEAVLDSIIGEHGVSPAAKRSIAARVSQLLKAESTGDVAAAEPAPVSA",
    "output": "Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTLAASSQRSQIIRSKFRSVLQLRIHRRNQDCTSDSDPWISASGPALAPALPTVPASFLVSPGVLSPEPAYCPWRAPKKESPKNSQHWKEPKVRGNLTYHLYMPPEQRQGPRANLQVERSTLGPPDPPLWEKNSQRPHPRMKPSSAGVSSPSPPSHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKAMLLERMRGGTPPRERPKPRREDKEAAAPWPRLKPKALGTTRLPSTVKASATNRRLKFSGATDPLGAAPAPASVPAPTPSPALAPTPTPAPVPAPAPAPFPTPPASLTLEEELQEAIRRAQLLPNRNIDDILEDQVEPDDLLPPVPLDFPGSFDLLSPSPDSEGFSSVFSSSLPSPTSSLSPSPRALTDSLDWLEALSGGPPLGSGPPGPSIFSADLSDPSGSLLWELLPDPW",
    "output": "Transcriptional coactivator. Stimulates the transcriptional activity of MEF2C. Stimulates MYOD1 activity in part via MEF2, resulting in an enhancement of skeletal muscle differentiation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLSADEKQLILHAWEKVHTHQEDFGAEALERMFTVYPQTKTYFHHFDLHHGSEQIRRHGKKVVVALENAVHHMDNLSAALCKLSDLHAYNLRVDPVNFKLLSHCFHVVLAGHLGEEYSPQVHVAYDKFLAAVSDVLAEKYR",
    "output": "Involved in oxygen transport from the lung to the various peripheral tissues."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKPNSHPEYVTTEVACSCGNTFTTRSTAKGGSIHVETCSACHPFYTGKQRVLDTAGRVAKFQQKYAKVQAKKGK",
    "output": "Binds the 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKVGVYGASGRIGKLLLEELKGGYKGLELSSVFVRQKCETDFSSFSHAPLVTNDLKAFVKACECVVDFSLPKGVDHLLDVLLECPKILVSGTTGLEKETLEKMQKLALKAPLLHAHNMSIGIMMLNQLAFLTSLKLKDADIEIVETHHNLKKDAPSGTALSLYETCTKARGYDEKNALITHREGLRSKESIGIATLRGGDVAGKHTIGFYLEGEYIELSHTATNRSIFAKGALEVALWLKDKAAKKYEISEMFG",
    "output": "Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKLSDFDFDLPEDLIATRPAVPRTSARLLVAKGRQISDSIVSDLPNWLSPGDRLVLNDTRVIPARLTGARHRDTAQGPMQARIEVTLLEPDAQGNWSALIKPLKKVKIAEEIIFSDRLRATLRAVKDGQGVLQFNLEGDDFDAALNAAGAMPLPPYIATRRPADERDKSDYQTVFAQNSGAVAAPTASLHFDKALLSELAARGVLFSYVTLHVGAGTFLPVKVEDVTTHKMHAEWGQVSAAAAAEINATKQAGKRVIPVGTTALRLIETAGREGQIKAWEGDTDIFIYPGFRFNVADALMTNFHLPKSTLMMLVSALMGYDEVRAIYDHAVAEKYRFFSYGDASLLIPQRD",
    "output": "Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNLRSLLASTPTQVLQPQHAALDLAITGLQTDSRRCQPGDLFLGMPGTQVDGGQFWPEAIAAGAVAVIVTPTALAQRPLSANPEACLILSDQMPVTAGAIAAAFYNQPAQTLKLIGVTGTNGKTTTTHLVEHFLNAADTKTALLGTLYNRWPGYSEVAQHTTPFATDLQAQLATAVDAGCQAAVMEVSSHALDQGRVNGCGFDVAVFTNLTQDHLDYHGTMEAYFAAKARLFAPPYLRGKAVINADDAYGQRLITMTPPGQCLTYSVVGTADFCTTDLQYGPTGVEGTIKTPDGAFPFRSPLVGQFNLANLLGAIAAGWTLGLPIETMLAVVPDFVGVPGRMERVVGQDSDPTVIVDYAHTPDSLENLLKAARPFIQGELICVFGCGGDRDRTKRPLMGEIAARLADRVIITSDNPRTEDPRQILADIVAGIPAASPVVVEADRAAAIRQAILSAQPGDGVLLAGKGHEDYQILGTTKIHFDDREQARLALAERQSA",
    "output": "Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSHSVEDIKSESRRLRGSLEQSLADAVTGALREDDQTLIKYHGSYQQDDRDIRDERRRQKLEPAYQFMIRTRTPGGVITPTQWLALDGIATRYANHSLRITTRQAFQFHGVIKRELKATMQAINATLIDTLAACGDVNRNVQVAANPLLSQAHATLYADAARVSEHLLPNTRAYYEIWLDEERVSGSGSEDEPIYGERYLPRKFKIGFAAPPLNDVDVFANDLGFIAILRDGQLLGYNVSIGGGMGASHGDAETWPRVANVIGFVTREQLLDIATAVVTTQRDFGNRAVRKRARFKYTIDDHGLDTIVAEIARRAGFALQPAQPFAFDHNGDRYGWVEGEDGLWHLTLSLPAGRIADTDTAAHLSGLRAIAQLNVGEFRMTPNQNLVIAGVLASERARVDALVAHYGLDAGNQSATALARGAMACVALPTCGLAMAEAERYLPDFGAALQPLLQQHGLAETPIVLRLSGCPNGCSRPYLAEIALVGKAPGRYNLMLGGDRRGQRLNTLYRENITEPEILAALEPLLARYAAERDHANDEGFGDFLHRAGVIALPPYPTHRRLDLELLA",
    "output": "Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKGHVARKRFGQNFLVDQGIIAAIISAVDPKRDETVVEIGPGLGAITEPLMARVDHLHVIEIDRDLIARLKKQHTPERMTVHEGDALAFDFASIGKNLRLVGNLPYNISTPLLFHLAEYVDVVHDMHFMLQKEVVERMVAEPGNADFGRMSVMLQYRFYLEWLIDVPPESFDPPPKVQSAVVRLIPKPVSELNAKSQEKLSQVALTAFSQRRKMLRNTMKTLLSDAAFTELGIDPTCRPEDVSVEDYVRIANYLS",
    "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDKWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMHKENITEPEILATLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD",
    "output": "Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MASTGSQASDIDEIFGFFSDGAPPTKKPRKLLPSLKTKKPRELVLVIGTGISAAVAPQVPALKSWKGLIQALLDAAIDFDLLEDEESKKFQKCLHEDKNLVHVAHDLIQKLSPRTSNVRSTFFKDCLYEVFDDLESKMEDSGKQLLQSVLHLMENGALVLTTNFDNLLELYAADQGKQLESLDLTDEKKVLEWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYENKSFLFLGCGWTVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKVISYGNDYADLPEYFKRLTCEISTRGRSGMVREGQLNGSSAAHSEIRGCST",
    "output": "May play a role in Cajal bodies formation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSVKARRISGRLETVVTKVNYAFDPVDDDKIIRNRLLTRTTTTRGEPPLKKLQKKFTSFVLEVDKEEENYNDCGRLAKAFLQELSTFEIPLLKSQAVVEANLREKESFNEVKDETERQIMQAKAEIEDLKKQLEESKIDRQHKEECETIRKLISAQPPRSETEKVIYELNKEIAELEAESTASWRLLELRKKQFALLMHVVDELQNTMEDEQKSLVDEIRSASEDQRNITDAMSVD",
    "output": "Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEENKSVAEGKAATGSLKESEETSAQNGELGEPEVQQTLKRTNSTESGGTGQKPPEEAPRRRFQIPRKSRDKRALQVISSGSREFEEILKILHSSYLDANSKASFSYKCARLVHNEFLEKEFTEKRRQLKFDGRLDKELVESYVFLLVDQEQMHSITEKGLHVGHSRMTTLGKPSMGVYLSRYADLLQANPLETGTTGDIFIFKVIKGKMKFVFDHIRNNQMDSFSGNGGLDPVPKHECHVLKNMNAVTALLGYRAFERTQYYFYEYGFDEVLKRPRHVCPYAVMSFGYKDELATRQPPLPTSGPVSFPTERSFDRSSFTLWRGQLLNKGKLLCYASLKSTSGPFIPYRLPERLDLDIVIKIEVIKKSIPAVLFYKETHNKPNEAKHGGIYSRLYEVVEKTRTGSHLQGLLQKIERENLALVKPLDDRGFMFLYFPSPMTSAYASAKTRLLHALFIYHESRLTQPVANVPVPPSFVPESHEFMPEVLTFVPALHFALHKSQSDTSADFNDVVEKHSRIYLKRRAEKLNKFKEYVLKPYDSRLDYKKSLYVAPRIKGHIESALRSYLFGSEAYTIPVDKAKEMLKENQRFQQFSPVSDYEPVEDDHDSNKYNKKCPVSYVETNSEKSSESTDWDIDKINGLINLIQKKKQSKPETDEPSGVGLKRKLDRQSEKAWKHRKCEENVHHDNEPGESAQSLISSLGGQDTDLRQETESLSSECIKMLLEKLADSCIDPAMAESLKTLKQNSTEELPSQKLKNLSQAHDTEREGAGQDQHIVYNDQTTDNQENTTCLSEEAQQAEGSHSDHSVLMEEKILDPPLESASPCPSNTAGNNCPAQGPNSLDLEMHWKLIPIAEANLTEEQLVYVSTEDALPNDPRAGHKRRGSRYSPLHETERQRPRHDRDYCRSLTTPSRTERNMLQSKHCHNGLIENTVLEVYNTFSEQLHDVLKQRDVPYMVPAAPPLLSSDDRVLKLSDCLCEQVSDICVQQYVDDLHTTLDSVVAAHINSCAVSRTGSPVTEIMAATEVHTFHPKQTVTEYPHVHEHFHVNDLHSDVREANPFSADHVYKVGEENAANGHALSHNSRDLSQETPEISTSGVTDLSEPHLAISNLINQMNPEVFNNLVKIITHVNKNSVKFYVHTEEENAICQNIKEYLLKLGNTECRPEKFLESKTKADKLLIIIQNEDIPNCIHRVPALVLLKRLPSVSFAGVDSLDDLKNHTYNEIFVSGGFIVSDESVLNPETVTIDELKKFLMFLEEINSPDANWQWKIHYKFHKRLKELGRLNTNALNILTLLTTYQKKNLVEILSYHLSCDPQNQQAPQLECLIKLQVQYMKQRHVLFLTEKDAARFPDYCDNGIVVTRMVDFMDNFSNLIGHHSPNNEEQRLSQLTNQGDETAPGEADSKEEEDMSLDSEDDTPPIEVCTDSWKPESQKQNISSLLELVDKDQTESPSTLNQGKTPTLDELQPITPVSVAGSTTGENSVSTGDELGSNTKDYNREVNLSHQFSHFSLLTHQTFLGSMYPTLTNPSQAEICFMNSYSQLTEPETSKNSERKQK",
    "output": "Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting further deposition of H3K9me3."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIISASTDYRAAAQRKLPPFLFHYIDGGAYNEQTLRRNTADLADIALRQRVLKNMSELSLETQLFGETQAMPVVLGPVGLSGMYARRGEVQAARAADKKGIPFTLSTLSVCPIEEVAPAIARPMWFQLYVLKDRGFMRNALTRAQAAGVKTLVFTVDMPVPGARYRDAHSGMSGPNAAARRLLQAIAHPQWAWDVGLNGKPHDLGNISAYLGKPTTLEDYMGWIATNFDPSISWKDLEWVREFWQGPMIIKGILDPEDAKDAVKFGADGIVVSNHGGRQLDGVLSTARALPAIADAVKGDITILADSGIRTGLDVVRMIALGADSVLLGRAFVYALATAGEAGVINLLTLIEQEMRVAMTLTGAKRIADINRDSLAVSERG",
    "output": "Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSQQPIRYEFIKACKQTGARLGRVHTPHGSFETPVFMPVGTLATVKTMSPEELKEMGADIILSNTYHLWLRPGHDIVKEAGGLHQFMNWNRAILTDSGGFQVFSLSEFRKIEEEGVHFRNHLNGDKLFLSPEKAMEIQNALGSDIMMAFDECPPYPAEYDYMKKSVERTSRWAERCLKAHNRPDEQGLFGIVQGGEYENLRKQSAKDLISLDFPGYAIGGLSVGEPKDVMNRVLEFTTPLLPADKPRYLMGVGSPDSLIDGAIRGVDMFDCVLPTRIARNGTLMTSEGRLVVKNAKYERDFRPIDEQCDCYTCRNYSRAYIRHLIRCNETFGIRLTSYHNLYFLLKLMGQVRDAIREDRLGDFREEFFERYGFNKPNAKSF",
    "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYCPNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA",
    "output": "One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNLQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKTGNFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPIFTFINKLDRDGREPLDLLEELEEVLGIASYPMNWPIGMGRSFEGLYDLYNQRLELYKGDERFASIEDGDKLFANNPFYEQAKEDIELLTEAGNEFSEEAILKGELTPVFFGSALTNFGVQTFLDSFLAFAPEPHGHKTTDDKVIDPLDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLARTGKSVKLSNVTQFMAESRENVENAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPELFMKVSAKNVMKQKSFHKGIEQLVQEGAIQLYTNYQTGEYMLGAVGQLQFEVFKHRMENEYNAEVIMTPMGKKTVRWIKEEDLDERMSSSRNILAKDRFNKPVFLFENDFSLHWFADKYPDIVLEEKM",
    "output": "Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGNCCWTQCFGLLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNNGEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKYSNKKTGSNPTSASDDSNGLEWENDFVSAEMDDNGNSEYSGFVNPVLELSDSGIRHSDTDQQTR",
    "output": "Necessary for adaptor protein complex 1 (AP-1)-dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/gamma1-adaptin, one of the subunits of the AP-1 adaptor complex. The direct interaction with AP1G1/gamma1-adaptin attenuates the release of the AP-1 complex from membranes. Regulates endosomal membrane traffic via association with AP-1 and KIF5B thus linking kinesin-based plus-end-directed microtubular transport to AP-1-dependent membrane traffic. May act as effector of AP-1 in calcium-induced endo-lysosome secretion. Inhibits Arp2/3 complex function; negatively regulates cell spreading, size and motility via intracellular sequestration of the Arp2/3 complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKLLKLTLISTALFSTAALAQAQQSVNVYSYDSFTSEWGAGPKVKQDFEKAHPQCAINFTPFESVGVLLNRVRLEGKKTKADIVLGLDNFFLEQAEKTGIFAPNNVDLTQLDLPTKWANKTFLPFDFGNYAFVYDKTKLQNPPKSLKELVERQDLSVIYQDPRTSSVGRGLLVWMNAVYPADKIQSAWKELDKHTVTVGKGWSDTYGAFLKGEADLVLSYSTSPLYHQLFEKKDNYAATDFAEGHITQVELAARVANHPNQCADDFMAFLISPTAQKHIVTANIMLPVIQGEIEPHFDALKVQQKTQTSINPMVNTEQLKNWISTWQTTLTK",
    "output": "Part of the ABC transporter complex ThiBPQ involved in thiamine import."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLSLAELKDKLDEMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRLTLEAIRVTQSDRDLFKHLISEATDYVAADYMRHANERRVHLDQALAFRRELYTSRKQLAAEQYKHVDMARELGEHNGAEGSLEADYQAASDHLNLVQTALRQQEKIERYEADLEELQIRFEEQNEVVAEAAEMQDENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAISALARAKELCHLPDLTPESAAEWLDTFQAKEQEATEKLLSLEQKMSVAQTAHSQFEQAYQLVAAINGPLARSEAWDVARELLRDGVNQRHLAEQVQPLRMRLSELEQRLREQQEAERLLAEFCKRQGKNFDIDELEALHQELEARIASLSESVSSASEQRMALRQEQEQLQSRIQHLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQEVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGAEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQIAEQLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPSLPIFGRAARENRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLSVAFEDDPEAEIRRLNGRRVELERALATHESDNQQQRLQFEQAKEGVSALNRLLPRLNLLADETLADRVDEIQERLDEAQEAARFVQQYGNQLAKLEPMVSVLQSDPEQFEQLKEDYAWSQQMQRDARQQAFALAEVVERRAHFSYSDSAEMLSGNSDLNEKLRQRLEQAEAERTRAREALRSHAAQLSQYSQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARQRRDELHAQLSNNRSRRNQLEKALTFCEAEMENLTRKLRKLERDYHEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQSVSFGQVNSVRLNVNVRETHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDEARRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTQAEDTPSEAS",
    "output": "Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKVLEQKQQVVAEVAAKLRDSKSTVIVDYRGLNVAQVTELRKQLREAGVEYKVYKNTLVRRATAEAGLTGLDEHLVGPTAIAFGVDDVIAPAKVLNEFAKNNEALTIKTGVIEGNISTADEVKALAELPSREGLLSMLANVLQAPVRQFALAAKAVAEQKEEQGA",
    "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPLSSQPSSSNLKRKQPTISSFFTKKPQLSQESISNDVLEKEERDEEREEVAKQEEGLRENGGTRSNNVDDDEDDVVAPASKRARTNGSHSQNTIETPKEKHVERPLPSDSIQKTELSKFASSPATEGETKERTKERERLHQKFVRRLGGPDCLIGIGRNTAPEAVPEEVGEGDEDDEPSPPPAAKGKATAKKGARKLTPMEKQVIDIKRKHMDTVLVVEVGYKFRFFGEDARTAAKELNIVCIPGKFRFDEHPSEAHLDRFASASIPVHRLHVHVKRLVSAGHKVGVVRQMETAALKAAGDNRNAPFGRKLTNLYTKGTYIDDMEGLEGSTASMSATGTSMATGYMLCITETNTKGWGNDEKVLVGIVAVQPATGDIVYDEFEDGFMRSEIETRLLHLAPCEVLIVGDLSKATEKLVQHLSGNKTNAFGDEIRVERAPKAKTAAAESHSHVSSFYAERMKKVNATNDVQASSLLQKVLNLSEQATICLSSMIKHMSEYGLEHVFQLTKYFQHFSSRSHMLLNANTLNSLEIYHNQTDHSTKGSLFWTLDRTQTRFGQRMLRKWVGRPLLNKLGLEERVDAVEELKNLERVALVEQMKCLLGRIKTDLEKSLIRVYYGKCTRPELLTLLQTLQMIAQEFAGVQSPADTGFSSPLISKAVASLPTILEDVVRFLDKINMHAAKNDDKYEFFRESEETDEITEHKLGIGAVEHDLEEHRSTAGEILGKRKVDYVTVAGIEYLIAVENKSPSIKKVPASWVKISGTKAVSRFHTPEVIRLLRQRDQHKEALAAGCDKAYATFLAEISASYQSFRDSVQSLATLDCLISLATIANQPGYVKPEYTNHTCIQVDQGRHPMVEQLLLDSYVPNDIDLDSDKTRALLVTGPNMGGKSSYVRQVALIAIMGQIGSYVPARSAKLGMLDAVFTRMGAFDNMLAGESTFMVELSETADILKQATPRSLVILDELGRGTSTHDGVAIAQAVLDYMIRSIRSLTLFITHYQHLSSMVHSFPDHELRNVHMRFTESGPTEEEITFLYEVREGVAHRSYGLNVARLANLPAPLIELAKQKSAELEQKIHRRRLAGLVRTVGDILADSAKADESLIERLISSAEQL",
    "output": "Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. Msh3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTNIPKSHPLVKIVNESFIDLPAPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGMYYGSYTFLETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAVVHLLFLHETGSNNPSGLTSDSDKIPFHPYYMIKDILGILLLILMLLLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAIIPLLHTSKQRSMMFRPFSQCLFWLLVADLLILTWIGGQPVEYPFITIGQLASILYFSILLILMPISSIIENHFLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMRELGMNAYLAVGHGSQNESLMSVIEYKGNPSEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMSNHNPLAHELIGASEQAGDRAWRLPLGDEFQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLSQFLLNRAGFNGEE",
    "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQRSPIEKANAFSKLFFRWPRPILKKGYRQKLELSDIYQIPSSDSADELSEMLEREWDRELATSKKNPKLVNALRRCFFWRFLFYGILLYFVEFTKAVQPLCLGRIIASYNAKNTYEREIAYYLALGLCLLFVVRTLFLHPAVFGLQHLGMQMRIALFSLIYKKILKMSSRVLDKIDTGQLVSLLSNNLNKFDEGVAVAHFVWIAPVQVVLLMGLIWNELTEFVFCGLGFLIMLALFQAWLGKKMMQYRDKRAGKINERLAITSEIIDNIQSVKVYCWEDAMEKIIDDIRQVELKLTRKVAYCRYFSSSAFFFSGFFVVFLSVVPYAFIHTIKLRRIFTTISYNIVLRMTVTRQFPSAIQTWYDSLGAIRKIQDFLHKDEHKTVEYNLTTKEVEMVNVTASWDEGIGELFEKVKQNDSERKMANGDDGLFFSNFSLHVTPVLKNISFKLEKGELLAIAGSTGSGKSSLLMMIMGELEPSDGKIKHSGRISYSPQVPWIMPGTIKDNIIFGLSYDEYRYTSVVNACQLEEDITVFPNKDKTVLGDGGITLSGGQRARISLARALYKDADLYLLDSPFSHLDVTTEKDIFESCLCKLMVNKTRILVTSKLEHLKKADKILLLHEGHCYFYGTFSELQGEKPDFSSQLLGSVHFDSFSAERRNSILTETFRRCSVSSGDGAGLGSYSETRKASFKQPPPEFNEKRKSSLIVNPITSNKKFSLVQTAMSYPQTNGMEDATSEPGERHFSLIPENELGEPTKPRSNIFKSELPFQAHRRQSVLALMTHSSTSPNKIHARRSAVRKMSMLSQTNFASSEIDIYSRRLSEDGSFEISEEINEEDLKECFADEEEIQNVTTTWSTYLRYVTTNRNLVFVLILCLVIFLAEVAASLAGLWIISGLAINTGSQTNDTSTDLSHLSVFSKFITNGSHYYIFYIYVGLADSFLALGVIRGLPLVHTLVTVSKDLHKQMLHSVLQGPMTAFNKMKAGRILNRFIKDTAIIDDMLPLTVFDFVQLILIVVGAICVVSVLQPYTLLAAIPVAVIFIMLRAYFLRTSQQLKQLESEARSPIFSHLITSLRGLWTVRAFGRQSYFETLFHKALNLHTANWFLYLSTLRWFQMRIDIVFVLFFIAVTFIAIATHDVGEGQVGIILTLAMNITSTLQWAVNSSIDVDGLMRSVSRVFKYIDIPPEGSETKNRHNANNPSDVLVIENKHLTKEWPSGGQMMVNNLTAKYTSDGRAVLQDLSFSVNAGQRVGLLGRTGAGKSTLLSALLRLLSTEGEIQIDGISWNSVSLQKWRKAFGVIPQKVFVFSGTFRKNLDPYEQWSDEEIWKVTEEVGLKSMIEQFPDKLNFVLVDGGYILSNGHKQLMCLARSILSKAKILLLDEPTAHLDPVTFQIIRKTLKHTFSNCTVILSEHRVEALLECQQFLVIEGCSVKQFDALQKLLTEASLFKQVFGHLDRAKLFTAHRRNSSKRKTRPKISALQEEAEEDLQETRL",
    "output": "Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3)(-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDKLTPSQWKVINKSYEPASTIKVIAGPGSGKTLTLLYKVLHLITVENIKPEEILIFSLTNKAVDSIIENLLSIFENSHTNKEIVHQIGCYTVHGLANRIVVENEGMINIIEEIGWRGLMKLLPPSKRTPHHFRSYKELEKVVKDYKLNNAKNNNPVIEKLVELMDNCKVMTNDDLIIRAKKYLELDSSDSDASSFTQDLRNKYKVVLIDEFQDLYPSLAPLITMICKGKQLIMFGDTNQSIYGFLGSNNEIMSQLDNLHPKNSTTVLKLFDNFRSTPEIISLASKIINRPLAEKQIIDDTDETPSELVRKLPSGVSPQIMTFDDLAAESEFIIDKITQLICSSAKFSDIAILSRTNSHLTAIASILKKYGIPYQKLKSQPDWMDDLRIQFLLDILKVCSLASDEKHNREFNTGDKWQSNFSILVTMSALKGIGDASIQALYKACSLKNLSIWKYLTMVPNFEWPLGLSIKKKMENYTSNLYEMIENDQVHQLDDPMELLEKVASITNNLNLNPTYFQSLSDAQSSLEFKTHLQEMAQVMKVSKSNKPPGISFVKWFLETYFDQTMVFHQSQQALQTTGPGTVKLSTIHSAKGLEFPIVFLTNGSMSNFPMDTNALYVGITRARNLLYMCNMKHERLVSKSSPYSRNIMSNNLFWTYYNKDLKRSVCDVKVTHGYNVQRYNQLRKNFGFYRAYSSLRGCKSVFRRI",
    "output": "Required for mitochondrial genome maintenance and mitochondrial DNA inheritance."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIVGLGIDLAEIDRFEKAQEKNSRFAEKVLTATEFELFSHYTGRRALEFLAGRFAVKEAFSKAYGTGIGQVKLQAVETLNDPQGKPYIKQDLFDGVVHVSLSHTATLVIAEVILERG",
    "output": "Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKGFKLKELLSHQKEIEKAEKLENDLKKKKSQELKKEEPTIVTASNLKKLEKKEKKADVKKEVAADTEEYQSQALSKKEKRKLKKELKKMQEQDATEAQKHMSGDEDESGDDREEEEEEEEEEEGRLDLEKLAKSDSESEDDSESENDSEEDEDVVAKEESEEKEEQEEEQDVPLSDVEFDSDADVVPHHKLTVNNTKAMKHALERVQLPWKKHSFQEHQSVTSETNTDEHIKDIYDDTERELAFYKQSLDAVLVARDELKRLKVPFKRPLDYFAEMVKSDEHMDKIKGKLIEEASDKKAREEARRQRQLKKFGKQVQNATLQKRQLEKRETLEKIKSLKNKRKHNEIDHSEFNVGVEEEVEGKRFDRGRPNGKRAAKNAKYGQGGMKRFKRKNDATSSADVSGFSSRKMKGKTNRPGKSRRARRF",
    "output": "Required for the processing of the 27S pre-rRNA. Probably involved in the step of the processing of the 27 SA precursor into the 27 SB intermediate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRYITAGESHGPQLTTILEGIPAGLPLVADDINAELARRQKGYGRGRRMQIEKDQVQIVSGVRHGQTIGAPIALIVENKDFAHWTKIMGAAPLTEQEKKEMKRQITRPRPGHADLNGAIKYGHRDMRNVLERSSARETTVRVAAGAVAKKVLAELGIKVAGHVIEIGGVRAEQTTYETIEQLQEITEASPVRCLDGEAGKKMMQAIDDAKASGDSIGGIVEVIVEGMPIGVGSYVHYDRKLDAKLAAAVMSINAFKGVEIGIGFEAAHRPGSQVHDEILWNEEEGYTRRTNHAGGLEGGMTTGMPVVVRGVMKPIPTLYKPLQSVDIETKESFSASIERSDSCAVPAASVVAEAVVAWELATALVEQFGADRMDCIRENIERHNEYAREF",
    "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEEGERSPLLSQETAGQKPLSVHRPPTSGCLGPVPREDQAEAWGCSCCPPETKHQALSGTPKKGPAPSLSPGSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPTDPMLGLALGGLVVSAASLAGCLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLLAARLLGALAARSGAAYGPGAHGEDRAGPQSPSPGAPPAAKPARG",
    "output": "Regulates maturation of the transmembrane metalloprotease ADAM10."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARIAGVDIPRDKRVVISLTYVFGIGRTTAQQVLKEAGVSEDTRVRDLTEEELGKIRDVIDKLKVEGDLRREVSLNIKRLIEIGSYRGIRHRRGLPVRGQNSKNNARTRKGPRRTVANKKK",
    "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTLSGSGSASDMSGQTVLSADDADIDVVGEGDEALDKDSECESTAGHTDEVGELGGKEIPRSPSGSGTEAEGKGESQQQQQEGIQNKPKNSLVKPPYSYIALITMSILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRQQQDSLREQTALMMQSFGAYSLASPYGRHYGLHPAAYTHPAALQYPYIPPVGHMLPPAVPLLPSSELTRKAFSSQLSPSLQLQLSSLSSTAASIIKSEPSSRPSFSIENIIGVSAASSAAPHTFLRPPVTVQSALMSHQPLALSRSTAAIGPILSVPTNLISGQFLPTAAAAVAKWPAQ",
    "output": "Transcriptional repressor that is an essential upstream regulator of neural crest determination and mesoderm induction. Functions by recruiting the transcriptional corepressor tle4. Also acts in a negative auto-regulator loop by inhibiting the transcription of its own gene."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPLYEFTFIAQQGLTQYELEGLVKGLSSLLTKNGAELLKYEYWGLLDFAYTIDKMNKGHYCMIYIKATPSSMDEFKRKVRLNEDILRFLCLKKDKLPKGDSLMIQASQV",
    "output": "Binds together with S18 to 16S ribosomal RNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MASKESKPSRTTRRGMEPPLRETWNQVLQELVKRQQQEEEEQQGLVSGKKKSWVSIDLLGTEGKDIKKVNIWEPCEKWFAQVVWGVLWVLQIVLWGCLMWEVRKGNQCQAEEVIALVSDPGGFQRVQHVETVPVTCVTKNFTQWGCQPEGAYPDPELEYRNISREILEEVYKQDWPWNTYHWPLWQMENMRQWMKENEKEYKERTNKTKEDIDDLVAGRIRGRFCVPYPYALLRCEEWCWYPESINQETGHAEKIKINCTKAKAVSCTEKMSLAAVQRVYWEKEDEESMKFLNIKACNISLRCQDEGKSPGGCVQGYPIPKGAEIIPEAMKYLRGKKSRYGGIKDKNGELKLPLSVRVWVRMANLSGWVNGTPPYWSARINGSTGINGTRWYGIGTLHHLGCNISSNPERGICNFTGELWIGGDKFPYYYTPSWNCSQNWTGHPVWHVFRYLDMTEHMTSRCIQRPKRHNITVGNGTITGNCSVTNWDGCNCTRSGNHLYNSTSGGLLVIICRQNSTITGIMGTNTNWTTMWNIYQNCSRCNNSSLDRTGSGTLGTVNNLKCSLPHRNESNKWTCKSQRDSYIAGRDFWGKVKAKYSCESNLGGLDSMMHQQMLLQRYQVIRVRAYTYGVVEMPQSYMEAQGENKRSRRNLQRKKRGIGLVIVLAIMAIIAAAGAGLGVANAVQQSYTRTAVQSLANATAAQQEVLEASYAMVQHIAKGIRILEARVARVEALVDRMMVYQELDCWHYQHYCVTSTRSEVANYVNWTRFKDNCTWQQWEEEIEQHEGNLSLLLREAALQVHIAQRDARRIPDAWKAIQEAFNWSSWFSWLKYIPWIIMGIVGLMCFRILMCVISMCLQAYKQVKQIRYTQVTVVIEAPVELEEKQKRNGDGTNGCASLERERRTSHRSFIQIWRATWWAWKTSPWRHNWRTMPYITLLPILVIWQWMEENGWNGENQHKKKKERVDCQDREQMPTLENDYVEL",
    "output": "The surface protein (SU) attaches the virus to the host cell by binding to its receptor. This interaction triggers the refolding of the transmembrane protein (TM) and is thought to activate its fusogenic potential by unmasking its fusion peptide. Fusion occurs at the host cell plasma membrane (By similarity).; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIKAFLIERRSWIAAFLFQQALMLFIAFVDPSISFGNVLYMVYLCILFFIIFLWFRYRKETAFYKSLKTWENNLDVTAINEPETPFEAMVERSIAGQTEHLKQTAARHRLALENEKDELMAWIHEVKTPLTAMHLIIDRMEEKALKSQLSYEWLRIHLLLDQQLHQKRISFIENDLSVEFIQLQPLIFKEIKDLQSWCIQKGIGFDIQLEAKEVLSDAKWLAFIIRQLLTNAVKYSEASEIEIKSFQKGEQTQLQVKDCGRGIDPKDVPRIFDKGFTSTTDHHDQASTGMGLYLAKKAAAPLLIHIDVESEFGAGTVFTLTFPIRNQFEHVISV",
    "output": "Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAPLKMLALVILLLGASLQHIHAARGTNVGRECCLKYFKGAIPLRKLKTWYQTSEDCSRDAIVFVTVQNKAICSDPNDKKVKKALKYLQSLERS",
    "output": "Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation (By similarity). In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MATSAIEQSAFAGQTALKSQNELVRKIGSFNGGRATMRRTVKSAPQSIWYGEDRPKYLGPFSEQTPSYLTGEFPGDYGWDTAGLSADPETFARNRELEVIHCRWAMLGALGCVFPEILSKNGVKFGEAVWFKAGSQIFSEGGLDYLGNPNLIHAQSILAVWASQVVLMGLIEGYRVGGGPLGEGLDKIYPGGAFDPLGLADDPEAFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPIENLFDHVADPVANNAWAYATNFVPGK",
    "output": "The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRLSRYFLPVLKENPSEAQIVSHRYMLRAGMIKQQAAGIYSWLPLGFKVLKRIEQIVHEEQIRAGHIPLLMPTLQPADLWRESGRYDDYGEEMLRITDRHKRDMLYGPTNEEMITDIFRSHVSSYKDLPLTLYHIQWKFRDEIRPRFGVMRGREFLMKDGYNFDLDYESAIHAYNRHMVSYLRTYERMGLQAIPMRAASGPIGGDNTHEFLVLASTGESEVFYDAAITDLKFGDRVVNYDDRAECEAIVKEWTAPYARTDETHDEAVFGQIPEERRRSSRGIEVGQIFYFGTKYSEPMGATVVTADGSRVPVHMGSHGIGVSRLLGAIIEASHDDKGIIWPEGVTPFHAGIVNLKQGDSSTDLACEALYRDLSARGLEPLYDDRDERAGAKFATMDLIGLPWRITVGPRGISAGKVELTNRRTGESEEMSSGAAVDRLAQIYAGI",
    "output": "Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDKKTARLSRSKRTRIKLRELGHTRLCVYRTPRHVYAQVISGDGSTVLVAASTVEKDVKAKCKYTGNVESAAIVGEIIADRCKEKGISQVAFDRSGYKYHGRVKALVEAAREHGLQF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED",
    "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFTPVEAKKSNLITVGRITGVFGIKGWVKLKSFTDPQDNVLEYSPLLLKTKHGVKECEIAEYQFRPQGLVVRLKGVDDRNAAEALAPVDVAIDKSLLPELDDDDFYWHQLEGLRVVTIYEGNTQDLGVVSKVMATGANDVLEVKPDAQSIDDRDRLVPYVLDLYVKKVDLSAECITVDWDPEF",
    "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MHWGMEMNVEQAIEYVKKNNVKFIRFQFVDILGFPKNVAYPVKAGEKGIEELREIFENGVWFDGSSITGFVGIEESDMLLKPDLSTLSVLPWRPEEKSVARVICDVYKDEKTPFEGDPRSRLKAILEELKKEMNGEYFVGPEPEFFLLKRDPHNPHRWVPADDGGYFDVEPLDDAPDIRRDIVLALENLGFHVEASHHEVAPGQHEVDFKFDNALKTADSVITFKMTIKNIAKKHGLKATFMPKPFFGMNGNGMHCHQSVWFNGEPSFYDPEGPYNGLSETCLSYIAGILSHAKALVAITNPTVNSYKRLVPGYEAPVNIAWANKNRSAIIRVPAARGKATRIEFRAPDPTCNPYLAFACMLAAGLDGIKKKMTAPEPVERNIFKMSEEEKKQLGIESVPANLAAALDELECDEVLQKALGKHIYENYMEIKRAEWDDFRTAVTDWETGKYLIY",
    "output": "Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Beta-glutamate is a much poorer substrate than alpha-glutamate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSRVFKKTCSNGKLSIYLGKRDFVDHVDMVEPIDGVVLVDPEYLKGRKMFVMLTCAFRYGHDDLDVIGLTFRKDLYVQVQQVVPAESSSPRGSLTVLQERLLHKLGDNAYPFTLQMVVNLPCSVTLQPGPDDTGKACGVDFEVKSFCAENLEEKVSKRDSVRLVIRKIQFAPLEPGPGPWARLCRRFLLSAQPLLLQAWMDKEVNYHGQPISVNVSINNSTNKVIKKIKISVDQITDVVLYSLDKYTKTVFVQEFTETIAANSTFSKSFAVTPLLADNCHKQGLALDGKLKQGDTNLASSTILRPGVDKELLGILVSYKVRVNLMVSCEGILGDLTASEVGVELPLILMHPKPSNEAASSEDIVIEEFAQQEPSGESQEALAAEGNEGS",
    "output": "May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENDLGVGYYQP",
    "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLSSGDLTSASWELVVRVDHANGEQQTEITLRVSGDLHIGGVMLKLVEQMNIAQDWSDYALWWEQKRCWLLKTHWTLDKCGVQADANLLFTPQHKMLRLRLPNAKTVRLRVSFSAVVFKAVADICKVLNIRRPEELSLLKPSSDYCKKKKKKEKNSKEPVIEDILNLESSSTSSGSPVSPGLYSKTMTPTYDPINGTPALSTMTWFGDSPLTEQNCSVLAFSQPPPSPDVLADMFQPRSLVDKAKMNAGWLDSSRSLMEQSIQEDEQLQLRFKYYTFFDLNPKYDAVRINQLYEQARWAVLLEEIDCTEEEMLIFAALQYHISKLSQCAEIQDFATKSEVDEVEAALSSLEVTLEGGKADNTLEDITDIPKLADYLKLFRPKKLMLKACKQYWFVFKDTSIAYFKNKELEQGEPIEKLNLRGCEIVPDVNVSGRKFGIKLLIPVADGMNEVYLRCDHEDQYARWMAACILASKGKTMADSSYQPEVISILSFLKMKNRNSSPLVASSLENMDMNPECLVSPCCAKKHKSKQLAARILEAHHNVAQMPLVEAKLQFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVAYNRLIRIDAVTGIPVTTWRFANMKQWNVNWEIRQVAIEFDQNVSIAFTCLSADCKIVHEYIGGYIFLSTRSKDQNETLDEDLFHKLTGGQD",
    "output": "Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAVAAAAAAAGPAGAGGGRAQRSGLLEVLVRDRWHKVLVNLSEDALVLSSEEGAAAYNGIGTATNGSFCRGAGAGHPGAGGAQPPDSPAGVRTAFTDLPEQVPESISNQKRGVKVLKQELGGLGISIKGGKENKMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREATPYVKKGSPVSEIGWETPPPESPRLGGSTSDPPSSQSFSFHRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDSATAQAWFSAIHSNVNDLLTRVIAEVREQLGKTGIAGSREIRHLGWLAEKVPGESKKQWKPALVVLTEKDLLIYDSMPRRKEAWFSPVHTYPLLATRLVHSGPGKGSPQAGVDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELIAEISTACTYKNQECRLTIHYENGFSITTEPQEGAFPKTIIQSPYEKLKMSSDDGIRMLYLDFGGKDGEIQLDLHSCPKPIVFIIHSFLSAKITRLGLVA",
    "output": "Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATATDRAPHQVQVHTPTTQRVDVQRRGYDVSGGGVKTFLPDRGPSTSQIIAVLVGVPTGGTLLLLSGLSLLGTIIGLAIATPVFTFFSPVIVPAVVTIGLAVIGILTAGACGLTGLMSLSWMINFIRQVHGTTVPDQLDSAKRRMADMADYVGQKTKDAGQEIQTKAQDVKRSSS",
    "output": "May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil. Probably interacts with both lipid and phospholipid moieties of lipid bodies. May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVKISDNSEIYDLIKDVTYLLGISIIEINTFRRRDEFKIQIVLYKSDNFSVDMLCDLHKMILLKLEAVLKYNVSLEISTPGINRKIKSDREFKIFEGKKIKLMLNNDFEEGFILRAERDGFIFKTEYKEVKILYSNVKKAKLS",
    "output": "Required for maturation of 30S ribosomal subunits."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVKIYPQVLSIAGSDSGGGSGIQADLKAFQTLGVFGTSVITCITAQNTQGVHGVYPLSVESVKAQILAIRDDFSIKAFKMGALCNAQIIECVADTLETCDFGLCVLDPVMVAKNGALLLEEEAILSLKKRLLPTTHLLTPNLPEVYALTGVQVRDDKSASKAMGVLRDLGVKNAVIKGGHTEHFQGEYSNDWVFLEDAEFILNAKRFNTKNTHGTGCTLSSLIVGLLAQGLDLKNAISKAKELLTIIIQNPLNIGHGHGPLNLWSIKELV",
    "output": "Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTHIVTDTPLWKKLSDHHWEVVGTHLRELFDTDPDRGVDLIVTAADLYIDYSKHRVTRETMGLLVDLARAAGVERHREAMFTGAHINTSEDRAVLHTALRANPERELIVDGQDVVGDVHTVLRRMGEFTDRVRSGAWRGATGERIRTVVNIGIGGSDLGPAMAYRALRHYVDGPEVRFVSNIDPADLLSNLTDLDPRTTLFVVVSKTFSTLETMTNASAARRWITEALGEHAVPRHFVAVSTDEERVTAFGITARNIFGFWEWVGGRYSVGSAAGLSVMIAIGRERFTEFLGGMRAIDEHFRTTPLESNAPVILGMLGVWYSSFFGADARAVLPYAHDLARFPAYLQQLTMESNGKSVRTDGTPVGTFTGEIFWGEPGTNGQHAFHQLLHQGTHLIPVDFLGFAEPIEDLPTLDGIGSVHDVLTANLFAQSKVLAFGKNADEVAADGTPSALVPHKVMSGNRPSTTILGAKLTPSTLGQLIALYEHQVFVQGIVWGIDSFDQWGVELGKTSALELGPALWDLDGAAYVGDSSTTGLIRTYRLARGERRCLP",
    "output": "Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNSAEIMADLSNHTPMMQQYLKVKKDYQHALLFYRMGDFYELFFEDAHLAAKLLGITLTHRGKANGNPIPMAGVPYHSAEGYLARLVKAGRTVAICEQVGEVTGKGPVERKVVRILTPGTLTDDALLTSYQSSNLVALCIHQNQIGFALLDLSAGIFKVQQQDYKPEQLPIELARLMPSEILIDEDLVDPNIIEQIKKHLDCPVTKRPNVDFNLNNAQKTLCDQFSVSTLSGFGLDPLPLAKAAAAALIHYAKETQKTALPHIRSILLEQSSDFIALDPITRRNLEIIEPLFEHGTSLFQLVNDCQTAMGGRLLSRTLMQPVRDTALLDARLDAIEQLIQGYHESPVRLVLKEIGDIERVLSRVALGSARPRDLVQLRHACAQIPFLRNALAPVVQAKKSKLLGQLDQELGDFKSLHQHLMAAIVENPPVLLRDGNVIAEGYDAELDELRQIRDHAGQFLIDLEIKERERTGISTLKIGYNRVSGYYIELTRAQAEQAPADYIRRQTLKNAERYITPELKSFEDKVLSSESRALAREKALFEALLENLRENIAHLQMMSSAIAQIDVIANFAHQARLNNWARPEFTPETGIKIQGGRHPVVEALSKAPFTPNDTFLDVQHRMAIITGPNMGGKSTFMRQTALISLLAYCGSYVPARAAKLGPIDRIFTRIGSADDLSTGKSTFMVEMTETSQILHHATNQSLVLMDEVGRGTSTYDGLSLAWACVVDLTKRVKCLCLFATHYFELTELGSEPGIDNYHVTAQELNGNLILLHKVQQGPASQSHGLQVAKLAGIPANVIKEAQKRLRILEKQQQQHLQTSVQSDLFATLDSEVTPSTQVIEKVIEVEVSSPALDLLKQIEVDNLTPRQALEQLYELKAALNS",
    "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSNVPADLKYTDEHEWIRTEADGTLTVGITDHAQSTLGDIVFLELPAVGKSVSAGDAVGVVESVKAASDIYSPVSGEIIAINEEAADSPEEVNSDAYGVWLFKIKLADGASTDKLIDADAYGKLID",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDLLAPLSAVVLTYREVSAEALGKVGQEMKRCIERRARAFPMYVLHTCSRVEAYLYGAPPEEVQEVAEAYRRYVDSVRVITGAEAARHLFRVAAGLDSILIGETDVLGQVEEAFDRQVRAGYTRGLLKTVVERAVRVGKRVRTETAISRGPRGLGSLSIIYVSRLLDLRQAKAAVLGAGAVGSGLAMELASRGVGKLYILNRTFEKAREVAAKTGGEARPLTREEVERCLRECDVVFSSVHSMEYVIDRVPEGASVKIVVDLGVPQTVAPGLPVKVVRIEDLRQVAEQYNAERAAEVAKAEAIVEEELAALPRLLARRYVEETVAALLETAMTAAEEEGARAGCDAAALAAKTTVKRVLLPLVEKMKKMAEDGQMEEAVRLANVLTQAVGRKT",
    "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSEVNRESLEAILPQLKCHFTWNLFREGSMSSHMEDRVCNQVEHLNSEEKATMYDLLAYIKHLDGESKAALECLGQAEDLRKSEHNDQSEIRRLVTWGNYAWIYYHMGRLSEAQAYVDKVRQVCQKFANPYSMECPELECEEGWTRLKCGRNERAKMCFEKALEEKPKDPECSSGMAIAMFRLEEKPEKQFSVDALKQAMELNPQNQYLKVLLALKLLRMGEEAEGERLIKDALGKAPNQTDVLQKAAQFYKKKGNLDRAIELLGKALRSTVNNSPLYSLVMCRYREILEQLQNKGDADSSERRQRMAELRRLTMEFMQKTLQRRRSPLNSYSDLIDFPEVERCYQMVISKESPDVEEEDLYERYCNLQEYHRKSEDLAALECLLQFPRNERSIEKEEVKEQT",
    "output": "IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication. Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription. Exhibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27. Normally, CDKN1B/p27 turnover is regulated by COPS5, which binds CDKN1B/p27 in the nucleus and exports it to the cytoplasm for ubiquitin-dependent degradation. IFIT3 sequesters COPS5 in the cytoplasm, thereby increasing nuclear CDKN1B/p27 protein levels. Up-regulates CDKN1A/p21 by down-regulating MYC, a repressor of CDKN1A/p21. Can negatively regulate the apoptotic effects of IFIT2 (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVKVYAPASSANMSVGFDVLGAAVTPVDGTLLGDVVSVEAADHFRLHNLGRFADKLPPEPRENIVYQCWERFCQALGKTIPVAMTLEKNMPIGSGLGSSACSVAAALVAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENGIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPQLAAALMKDVIAEPYRARLLPGFSQARQAVSEIGALASGISGSGPTLFALCDKPETAQRVADWLSKHYLQNQEGFVHICRLDTAGARVVG",
    "output": "Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIRASDISVRLAGRQVLHGISLDAAPGAMTAIVGPNGSGKTTTLKAISGELTPSAGKVTINGRDIASLKPWELALKRGVLPQSTVISFPFTVREIVRLGLMANGGEASAHGRIADQALEAVDLAGFSGRFYQELSGGEQQRVQLARVLCQISAPVAAGEPRYLLLDEPVSSLDIRHQLTIMRLARQFCADGGGVVAVMHDLNLTSMFADQIVMMKAGRIRARGAPKDVLTDETMEAVFGCRMRVSVAPAHDIPFVLPQSATM",
    "output": "Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPLRLIFMGTPDFAVPTLLELAGHGHEIVAVYTRAPKPGGRRGLALVPTPIESEARRLGIPVLTPKTLKTEEALAEFRAHEADAAVVVAYGMILPQAILDAPKLGCYNLHASLLPRWRGAAPINRAIMAGDAESGVMVMKMDVGLDTGDVAMAELLAITDAMTASDLHDKLSRIGADLMVRAMAALERGGLTLTKQAEDGVTYAAKIEKAEARIDWTKPAHAVLRHIHGLSPFPGAWSEITIDGEAVRLKILRCALARGTGEPGTVVDDELTIACADSAIRITELQRAGKSPMKAADFLRGTRVAPGLRFG",
    "output": "Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIMSLGPYASFIVTSYAAAALVVAILIGWIATDYRSQTRRLRDLDRSGITRRSGRSAMDRP",
    "output": "Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIRTDAKDGALVLFSGGQDSATCVAWALERYQTVETLGFDYGQRHRVELECREGVRDALKRRFPQWSHKLGDDHLIDLSVLGSISDTAMTRAIEIETASNGLPNTFVPGRNLLFMTIAAAIAYRRGLRALVGGMCETDFSGYPDCRDDTMKALQVALNLGMDTRFVLETPLMWLDKADTWRLAEQLGGAPLVELIRVETHTCYVGERSELHDWGFGCGECPACKLRKRGYDAYLRGESVTEAPA",
    "output": "Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAAKLSFSDLWSDVCAVRDRSPLVHSITNLVVINFNANVLLAAGASPVMAHAHEEVADMVGIAQALVLNIGTLDPYWIESMQLALRAAAKRGIPVVLDPVGAGATKYRNEAIEQLLMTSLPTVVRGNGSEIMSVAGSAAQTRGVDSSAAATDALGAAQSLVQRTQGVVCVSGQIDHILDASHRWAQLSNGHAWMTRITGVGCSATALIGAFCAVQPDAWRATVAAMALLGVVGEVAAEKVIARGKGVGSLQMALLDELQLLDQGTFEQRLKLEVAQW",
    "output": "Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGVVTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIVK",
    "output": "Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDATDVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETASLICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLTFGILYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPYGFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTDSMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE",
    "output": "Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MASHNENDDIPMLPISDPSSRTRARAFTSRSRSVSLSNPTSSIEGFDTSTVVLGYTGPLRTQRRPPLVQMSGPLTSTRKHEPLFLPHPSSDSVGVSSQPERYPSFAALEHKNSSEDEFVLKHANLLRSGQLGMCNDPYCTTCPSYYNRKAAQIPTSRVSALFDSTFHNALYDDAKGWARRFASSVNRYLPGIMNPHAKEVQTWTKFFALSCLLAIFIDPLFFFLIKVQEQNKCIMIDWPMTKAFVAVRSVTDVIFTMNILLQFRLAYVARESTVVGAGQLVSHPKKIALHYLKGKFFLDLFIVMPLPQILILWIIPAHLGASGANYAKNLLRAAVLFQYIPKLYRLLPFLAGQTPTGFIFESAWANFVINLLTFMLAGHVVGSCWYLFGLQRVNQCLRNACGNFGRECQDLIDCGNGNSSVLVRATWKDNASANACFQEDGFPYGIYLKAVNLTNHSNLFTRYSYSLFWGFQQISTLAGNQVPSYFLGEVFFTMGIIGLGLLLFALLIGNMQNFLQALGKRNLEMTLRRRDVEQWMSHRRLPDGIRRRVREAERFNWAATRGVNEELLFENMPDDLQRDIRRHLFKFLKKVRIFSLMDEPILDAIRERLKQRTYIGSSTVLHRGGLVEKMVFIVRGEMESIGEDGSVLPLYEGDVCGEELLTWCLERSSVNPDGTRIRMPSKGLLSSRNVRCVTNVEAFSLSVADLEDVTSLFSRFLRSHRVQGAIRYDSPYWRLRAARQIQVAWRYRRRRLHRLCTPQSSYSL",
    "output": "Probable cyclic nucleotide-gated ion channel."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MHAYRTHTCGQLREQNAGETVRLSGWIHRKRDHGNLLFIDLRDHYGLTQCVIDTSNPNFGTVEGLRVESVITVTGKVVARTTETVNDKLPTGRIEVQVKELEVQSAADQVPLQVNSEQDAGEELRLRYRFLDLRREKMQRNMVLRSNVIASVRRRMIEQGFTEFQTPILTASSPEGARDFLVPARNHPGKFYALPQAPQQFKQLLMVSGFDRYFQIAPCFRDEDSRADRSPGEFYQLDFEMSFVTQDDVFAAIEPVIHGIFEEFSGFTGVKKSVSPYPFVRIPFDEAMLKYGSDKPDLRNPLVIVDVTDVFRRPDVEFKAFKGVIEKGGVVRTIRVPGVADRPRSFYDKLNDWARGLGAPGLGYIVFEGGAGKGPIAKFVPEAAQAALRQATGAVDGDAVFFVCDQPGPAAKLAGQARTEIATQLDLIAKDRFEFCWIVDFPMYEYDEERKKIDFSHNPFSMPQGGLEALETQDPLTIKAFQYDIVCNGVELSSGAIRNHRPEIMYKAFEIAGYAAEDLEAKFGGMLSAFKLGAPPHGGSAPGIDRMVMLLADEPNIREVILFPLNQRAEDLLMQAPNGVAPERLKELHLKLDLPKPKIAG",
    "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAWIPLLLPLLTLCTGSEASYELTQPPSVSVSLGQMARITCSGEALPKKYAYWYQQKPGQFPVLVIYKDSERPSGIPERFSGSSSGTIVTLTISGVQAEDEADYYCLSADSSGTY",
    "output": "V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVFDSFDIKSLIRPVIDFPKPGVIFRDITPLFQSPKALRLVMDSFAHRYVEADFTHIGAMDARGFLIGSVLAYQLNKPLVLFRKQGKLPADVLAEGYATEYGEAFLEVHADSLCEGDSVVMFDDLIATGGTLIAAANLIRRMGARVHEAAAIIDLPELGGSQRLEDMGIPTFCLTQFALTDK",
    "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKTWSHVALLACLSIKWLTCVMADSIYCDDPDMCSMTKRFLRFGRALDTTDPFIRLRRQFYRIGRGGYQPYQDKRFLRFGRSEQPDVDDYLRDVVLQSEEPLYRKRRSTEAGGQSEEMTHRTARSAPEPAAENREIMKRETGAEDLDEEKRFMRFGRGDEEAEKRFMRFGKSFMRFGRDMSDVDKRFMRFGKRFMRFGREPGTDKRFMRFGREPGADKRFMRFGKSFDGEEENDDDLYYNESDADSNDDVDKRFMRFGKSAEEKRFMRFGKSEDASRDKKEFLRIGKRESRSAEVENNIQIAAKQS",
    "output": "FMRFamide induces contractions in visceral and somatic musculature as well as in the heart. May play a role as cotransmitters or modulators in a number of significant neuronal systems."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSTENPDSVAAAEELHALRVEAQVLRRQLAQSPEQVRELESKVDSLSIRNSKLMDTLKEARQQLIALREEVDRLGQPPSGYGVLLSVHEDKTVDVFTSGRKMRLTCSPNIDTDTLALGQTVRLNEALTIVEAGTYEQVGEISTLREVLDDGLRALVVGHADEERIVWLAAPLAAVFADPEADIIAYDADSPTRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVHYDDIGGLGRQIEQIRDAVELPFLHKDLFHEYSLRPPKGVLLYGPPGCGKTLIAKAVANSLAKKIAEARGQDSKDAKSYFLNIKGPELLNKFVGETERHIRMIFQRAREKASEGTPVIVFFDEMDSIFRTRGSGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAESAQDIFSKYLVDGLPINADDLAEFGGDRTACLKAMIVRVVDRMYAESEENRFLEVTYANGDKEVLFFKDFNSGAMIQNIVDRAKKYAIKSVLDTGAPGLRVQHLFDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKNASASRAIDTESNTGQYL",
    "output": "ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNKPQSFFHLHLISDATGETLLAAGRAASAQYKDARAIEHIYPLIRTEKQVAKVFEDIEEEPGIILYTVVDQKLARGIDERCATMGLPCVSVLEPVLTVFQSYLGTPAGRRVGAQHVLDAEYFRRIDALNFTMDHDDGQLPANMDDADVVLIGISRTSKTPTSIYLANRGIKTANIPIVLGVPVPESLVSASKPLIVGLIATAERISHVRQNRILGNSSSYVPTDYVDRAAINEELAYARQICTRHGWPMIDVSRRSIEETAAAIVALRGKNR",
    "output": "Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSHTVKIYDTCIGCTQCVRACPTDVLEMVPWDGCKAAQVASSPRTEDCVGCKRCETACPTDFLSIRVYLGAETTRSMGLAY",
    "output": "Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNAIVALCHFCELHGPRTLFCTEVLHAPLPQGDGNEDSPGQGEQAEEEEGGIQMNSRMRAHSPAEGASVESSSPGPKKSDMCEGCRSLAAGHPGYISHDKETSIKYVSHQHPSHPQLFSIVRQACVRSLSCEVCPGREGPIFFGDEQHGFVFSHTFFIKDSLARGFQRWYSIITIMMDRIYLINSWPFLLGKVRGIIDELQGKALKVFEAEQFGCPQRAQRMNTAFTPFLHQRNGNAARSLTSLTSDDNLWACLHTSFAWLLKACGSRLTEKLLEGAPTEDTLVQMEKLADLEEESESWDNSEAEEEEKAPVLPESTEGRELTQGPAESSSLSGCGSWQPRKLPVFKSLRHMRQVLGAPSFRMLAWHVLMGNQVIWKSRDVDLVQSAFEVLRTMLPVGCVRIIPYSSQYEEAYRCNFLGLSPHVQIPPHVLSSEFAVIVEVHAAARSTLHPVGCEDDQSLSKYEFVVTSGSPVAADRVGPTILNKIEAALTNQNLSVDVVDQCLVCLKEEWMNKVKVLFKFTKVDSRPKEDTQKLLSILGASEEDNVKLLKFWMTGLSKTYKSHLMSTVRSPTASESRN",
    "output": "Multi-functional protein, involved in both the cellular response to amino acid availability and in the regulation of glycolysis . GTPase-activating protein that plays a key role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade controlling the MiT/TFE factors TFEB and TFE3 . Regulates glycolysis by binding to lactate dehydrogenase LDHA, acting as an uncompetitive inhibitor . Activates mTORC1 by acting as a GTPase-activating protein: specifically stimulates GTP hydrolysis by RRAGC/RagC or RRAGD/RagD, promoting the conversion to the GDP-bound state of RRAGC/RagC or RRAGD/RagD, and thereby activating the kinase activity of mTORC1 . The GTPase-activating activity is inhibited during starvation and activated in presence of nutrients . Acts as a key component for mTORC1-dependent control of the MiT/TFE factors TFEB and TFE3, while it is not involved in mTORC1-dependent phosphorylation of canonical RPS6KB1/S6K1 and EIF4EBP1/4E-BP1 . In low-amino acid conditions, the lysosomal folliculin complex (LFC) is formed on the membrane of lysosomes, which inhibits the GTPase-activating activity of FLCN, inactivates mTORC1 and maximizes nuclear translocation of TFEB and TFE3 . Upon amino acid restimulation, RRAGA/RagA (or RRAGB/RagB) nucleotide exchange promotes disassembly of the LFC complex and liberates the GTPase-activating activity of FLCN, leading to activation of mTORC1 and subsequent cytoplasmic retention of TFEB and TFE3 . Indirectly acts as a positive regulator of Wnt signaling by promoting mTOR-dependent cytoplasmic retention of MiT/TFE factor TFE3 . Required for the exit of hematopoietic stem cell from pluripotency by promoting mTOR-dependent cytoplasmic retention of TFE3, thereby increasing Wnt signaling . Acts as an inhibitor of browning of adipose tissue by regulating mTOR-dependent cytoplasmic retention of TFE3 (By similarity). Involved in the control of embryonic stem cells differentiation; together with LAMTOR1 it is necessary to recruit and activate RRAGC/RagC and RRAGD/RagD at the lysosomes, and to induce exit of embryonic stem cells from pluripotency via non-canonical, mTOR-independent TFE3 inactivation (By similarity). In response to flow stress, regulates STK11/LKB1 accumulation and mTORC1 activation through primary cilia: may act by recruiting STK11/LKB1 to primary cilia for activation of AMPK resided at basal bodies, causing mTORC1 down-regulation . Together with FNIP1 and/or FNIP2, regulates autophagy: following phosphorylation by ULK1, interacts with GABARAP and promotes autophagy . Required for starvation-induced perinuclear clustering of lysosomes by promoting association of RILP with its effector RAB34 ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEKTCIDALPLTMNSSEKQETVCIFGTGDFGRSLGLKMLQCGYSVVFGSRNPQKTTLLPSGAEVLSYSEAAKKSGIIIIAIHREHYDFLTELTEVLNGKILVDISNNLKINQYPESNAEYLAHLVPGAHVVKAFNTISAWALQSGALDASRQVFVCGNDSKAKQRVMDIVRNLGLTPMDQGSLMAAKEIEKYPLQLFPMWRFPFYLSAVLCVFLFFYCVIRDVIYPYVYEKKDNTFRMAISIPNRIFPITALTLLALVYLPGVIAAILQLYRGTKYRRFPDWLDHWMLCRKQLGLVALGFAFLHVLYTLVIPIRYYVRWRLGNLTVTQAILKKENPFSTSSAWLSDSYVALGILGFFLFVLLGITSLPSVSNAVNWREFRFVQSKLGYLTLILCTAHTLVYGGKRFLSPSNLRWYLPAAYVLGLIIPCTVLVIKFVLIMPCVDNTLTRIRQGWERNSKH",
    "output": "Integral membrane protein that functions as NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate . Can also reduce Cu(2+) to Cu(1+) (By similarity). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance . Involved in inflammatory arthritis, through the regulation of inflammatory cytokines . Inhibits anchorage-independent cell proliferation ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNKALLPLLLCCFIFPASGKDAGWQWYNEKINPKEKENKPVPAAPRQEPDIMQKLAALQTATKRALYEAILYPGVDNFVKYFRLQNYWAQQAGLFTMSARKAMLAHPELDYNLQYSHYNGTVRNQLAADQAQQRQAIAKLAEHYGIMFFYRGQDPIDGQLAQVINGFRDTYGLSVIPVSVDGVINPLLPDSRTDQGQAQRLGVKYFPAMMLVDPKQGSVRPLSYGFISQDDLAKQFLNVSEDFKPNF",
    "output": "Involved in F pilus assembly."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLPGLELSQQPIEARRAPPQPTQISLPKGSEWRFEVAFGNTTRVKLLAGTAELFGTELATSQTYTFSGTKAAIYTWHGCTLEVGAGDPVPIGPVGSAPVPPGPGNGGCQVEYIAEETPMAEYANVHFALETMRHDAKAAGRDGPRVLILGPEDAGKTSLAKILTGYATKMGRQPLVVNLDPSEGMLSVPGALTATAFRSMIDVEEGWGSSPMSGPSPIPVKLPLVYFYGLPACLDGDGSYYKAIVSRLALAVTGRMAEDSDAREAGVIIDTPGIIGQGKGASEDVIHHIVTEFSISTILVIGSERLYSTMVKNYDNKPIATSATAAASDERISVVKLTKSGGCVDRDATFMKYVRESQIRSYFFGSPVPSTASSALSLSSTTTGTTMTLSPHTSQVDFNSLSIYSITIATEGEEDEYDPSKFDSFLPGGHEENDHNTSLTGTTSLQPPSGLLPGLRSELPSATTGFPSASTSSTTPFTNLPSPAPMSLANTLLAITNAAPNASLDEVRDASIMGFIYIADVDEKKGQGGKLRLLAPVGGRVPNRAMIWGRKWPGEVVGLIG",
    "output": "Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDLAESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE",
    "output": "Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKQFLDFLPLVVFFAFYKIYDIYAATAALIVATAIVLIYSWVRFRKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQRMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLIFTLLSGIYIYRHMPQEDKS",
    "output": "Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLPPPKSAAVQIVRPPSPSSEKAKEKEKKHSPEKRETAQRICRNVMIYGYCKYQDQGCIYYHPPAGADPSTPQNSSPVAHAPTPSAPTPLAGTPAREKPTLSIEHLAAPVFVPKGLDSSPRASTPSVPTPSAPTPPVWPSLPSTGLLPRQDVQVSAQPSHAQLSATASPMAYDDPSHIALSAAHAHAQAQALTHGILDPHAHAPPVDQSMYLPPRQPLDYNLYAAPLPSIGGNPLYPTHPHAFFVSDDLRRAIQAKQEAVYAGANGASAPGLPQELGVYHSLIPLPLPAPTAQCPPTQSQPSKVYGLPSPVYRATSEVDGNTYCLRRVEGFKLVNQLAFASMDTWRRMRHPNIVGLKEAFTTKTFGDNSLIMVYDYHPLSTTLYDEYLSPNPPEPSPASALANQPPKRRSSPPERILWSYVTQIANALKAIHSSGLAVRNLDASKILLTGKNRIRLNGCGVWDVLAFDNKTPVQAFQQEDLLSFGKLIISLTCDFFQPTLPFSLPLEHISRHYSSDLSNLILYLISKPAQGQIKSIDEVVKMMGPRILNELDAVQSYADVLENELGAEVENGRIVRLLTKLGFINERAEFELDPRWSDTGDRYILKLFRDYVFHSVGVDGKPILDLSHVLVCLNKLDAGLDERVMLVSRDDQSCLVVSYREIKHCIEAAFNELKNAGNNHRVHR",
    "output": "Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLVKPMACYFEIWTRKVTTIEDFSLAIANRFKQMGSHSDSEVDWDNEEEVWEDEVHEFCCLFCDSTFTCLKDLWSHCKEAHNFDFYQVKQQNNLDFYACIKLVNYIRSQVKEGKTPDLDKLSDILRSDEYMISVLPDDSVLFSLGDELDSDFEDDNTLEIEVENPADVSKDAEIKKLKLQNQLLISQLEEIRKDKMNELTSQTTDQLSVTPKKADNDSYYFESYAGNDIHFLMLNDSVRTEGYRDFVYHNKHIFAGKTVLDVGCGTGILSMFCAKAGAKKVYAVDNSDIIQMAISNAFENGLADQITFIRGKIEDISLPVGKVDIIISEWMGYALTFESMIDSVLVARDRFLAPSGIMAPSETRLVLTATTNTELLEEPIDFWSDVYGFKMNGMKDASYKGVSVQVVPQTYVNAKPVVFARFNMHTCKVQDVSFTSPFSLIIDNEGPLCAFTLWFDTYFTTKRTQPIPEAIDEACGFTTGPQGTPTHWKQCVLLLRNRPFLQKGTRVEGTISFSKNKKNNRDLDISVHWNVNGKADSQSYVLN",
    "output": "Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in ribosomal protein rps2."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLDKTRLRIAMQKSGRLSEDSQALLARCGIKINLHQQRLIAFAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLTRRAQGDDPRYTLLRRLDFGACRLSLAMPIDAAYDGARGLQDCRIATSYPHLLKRYLDGQGVRFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMPPAKQALIERLMTRIQGVIQARESKYIMLHAPSDRLEEIMALLPGAERPTLLPLAGDKRRVAMHMVSSETLFWETMEQLKALGASSILVLPIEKMME",
    "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPTITLPDGSQRSFDHPVTVAEVAQSIGAGLAKATLAGKVDGKLVDACDLIERDASLQIITPKDEEGLEIIRHSCAHLVGHAVKQLYPNAKMVIGPVIDEGFYYDIAIDRPFTPEDMAAIEKRMAELIDKDYDVIKKVTPRAEVIEVFTSRGEDYKLRLVDDMPDEQAMGLYYHEEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDSKNEQLQRIYGTAWADKKQLAAYIQRIEEAEKRDHRRIGKQLDLFHTQEEAPGMVFWHPAGWTLYQNLEQYMRQVQRENGYQEVRTPQVVDRILWEKSGHWSNYAENMFTTSSENRDYAVKPMNCPCHVQIFNQGLKSYRDLPLRMAEFGACHRNEPSGALHGIMRVRGFTQDDAHIFCTEEQVKKEAADFIKLTLKVYADFGFSDIAMKLSTRPAKRVGSDELWDRAEGALAEALNESGLAWEYQPGEGAFYGPKIEFTLRDCLGRNWQCGTLQYDPNLPERLDASYVAEDNSRQRPVMLHRAILGSFERFIGMLIEHYAGAFPAWLAPTQAVIMNITDKQAAFAIEVEKTLVQSGFRAKCDLRNEKIGFKIREHTLLKTPYLLVIGDREVETRSVAVRSREGVDMGSMPLEQFAQLLAQAVSRRGRQESE",
    "output": "Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPKILVSAGEASGDLYASLVVQELRRIMPDAEFFGCTGPRLRAAGVRTIVDSADLAVVGLIEVVAHIPRIYGEFRKLLRAAREERPLLAILTDSPDFHLRVARKLHRQEVPVVYLVAPQAWAWRRGRVREMRRTIRRLLCIFPFEEEFFRRYGVPATYIGHPLAGLVHPALSREEFFKKHRLAAERPLVSVLPGSRRGEAARHIPALLDAVDRIYREQAVNVVLPASATTGVAFFQERMGNSPIRVIEGESWDAMAHSDLALAASGTVTVEAALLGTPMVTFYKVTGVSWLAGKFLVDIPFYSMVNLIAGRAVVPELMQSQMTGENLAREALRLLQGGRDREEMKAGLAQVKEKLAGRTGAPGRAALAIQEILEGQVTHVS",
    "output": "Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMNPLIIKLGGVLLDSEEALERLFTALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKDGLRVTPADQIGIITGALAGTANKTLLAWAKKHHIASVGLFLGDGDSVNVTQLDEALGHVGLAQPGSPKLINMLLENGFLPVVSSIGVTDDGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTASKAEQLIDQGIITDGMIVKVNAALDAARALGRPVDIASWRHAEQLPALFNGTPIGTRILA",
    "output": "Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKQYRNFVDGKWVESSKTFQDVTPIDGSVVAVVHEADRDLVDAAVKAGHRALEGEWGRTTAAQRVDWLRRIANEMERRQQDFLDAEMADTGKPLSMAATIDIPRGIANFRNFADILATAPVDSHRLDLPDGAYALNYAARKPLGVVGVISPWNLPLLLLTWKVAPALACGNAVVVKPSEDTPGTATLLAEVMEAVGIPPGVFNLVHGFGPNSAGEFISQHPDISAITFTGESKTGSTIMRAAAEGVKPVSFELGGKNAAVIFADCDFEKMLDGMMRALFLNSGQVCLCSERVYVERPIFDRFCVALAERIKALKVDWPHETDTQMGPLISSKHRDKVLSYFELARQEGATFLAGGGVPRFGDERDNGAWVEPTVIAGLSDDARVVREEIFGPICHVTPFDSESEVIRRANDTRYGLAATIWTTNLSRAHRVSELMRVGISWVNTWFLRDLRTPFGGAGLSGIGREGGMHSLNFYSELTNVCVRIDKESPDV",
    "output": "Involved in the modified meta-cleavage pathway for 2-aminophenol catabolism. The enzyme is also active toward 2-hydroxymuconic 6-semialdehyde, acetaldehyde, propionaldehyde, and butyraldehyde."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVVAVYPGTFDPLTRGHEDLVRRASSIFDTLVVGVADSRAKKPFFSLEERLKIANEVLGHYPNVKVMGFTGLLKDFVRANDARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVEKWLTEKVAAMAQGPSA",
    "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKYENLVTRFLKYVKTETRSNEDSTTIPSTQTQVEFIKGLANELKGLGLQNVHISDESGYVFATLPSNLEDDANTKVVGFISHVDTADFNAHNVQPQIVENYDGESDIKLDEAGNFVLTTAEFPNLRNYKGHDLITTDGSTLLGADDKSGVAEIMSAMEYLQAHPEIKHGEIKVGFGPDEEIGTGADNFNVEDFGADIAYTVDGGPLGELEYETFNAAQAKLTFKGKDVHTGTAKNVMVNAIQLAINYQNSLPADEVPEKTEGREGFFHLFKFDGSVEEAHTTYIIRDHDRKHFEERKQLMLDIAERMNTELGEERVVIDLQDQYYNMREVLEKDMTAVDIAKEAMEDLGITPEIYPVRGGTDGSKISFMGLPTPNLFAGGENMHGRYEYVSTQVMEKATDVILEIVKLLAK",
    "output": "Cleaves the N-terminal amino acid of tripeptides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLSVYEKGNALDKRVLEEWLLSEDILMENAAMALERAVLQNASLGAKVIILCGSGDNGGDGYTLARRLVGRFKTLVFEMKLAKSPMCQLQKERAKKVGVVIKAWEEKNEDLECDVLVDCVVGSAFKGGLEPFLDFESLSQKARFKIACDIPSGIDSKGRVDKRAFKADTTISMGAIKSCLLSDKAKDYIGELKVGHLGVFNQIYEIPTDTFLLEKSDLKLPLRDRKNAHKGDYGHAHVLLGKHSGAGLLSALSALSFGSGVVSIQALECEITSNNKPLELVFCENFPKKLSAFALGMGLENIPKDFKKWLELAPCVLDAGVFYHKEVLQALEKEVILTPHPKEFLSLLKSVGINISMLELLDNKLEIARDFSQKYPKVVLLLKGANTLIAHQGRVFINNLGSVALAKAGSGDVLAGLIVSLLSQNYTPLDAAINASLAHALAGLEFKNHYALTPLDLIEKIKRL",
    "output": "Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKDYVVKATAYDGEVRAIALRATEMVKEACKRQGTWPTASAALGRTMMGGALMASMLKGKDKLTVRIQGNGPIGEIIVDAHASGATRGTVTNPHVSPELNSKGKLDVARVVGTEGTLSVVKDLGMKEPFTGSVPIVSGEIGDDFTYYFANSEQTPSSVGVGVLVNPDESVLAAGGFVIQLLPGAKEATITEIEKRIGETPPISKLVEQGKTPEEIINGLLGEENVKFLETKPVFFECSCSKERIGNAIISLGTKEIEAMITEDGGAETVCHFCNESYSFTEAELKALLEEAESKR",
    "output": "Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTLAGQTIAVIDYGMGNLRSVSKALEHVAGGKQVIVTADPAVVAAAERVVFPGQGAMPDCMRELDARGLRTAVLAAAKDKPFLGICVGEQMLFEHSDEGNVPALGVFAGNVKRFPDEKMHLPTGERLKVPHMGWNEVRQKPHALWSGIADGSRFYFVHSYFVEPADLALVTGICEYGVPFTCAVGRDNIFAVQFHPEKSARDGLQLLKNFVEWQP",
    "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDSITSAASVVAAGLAVGLAAIGPGIGQGTASGGAVEGIARQPEAEGKIRGTLLLSLAFMESLTIYGLVVALVLLFANPFA",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASLKDIRAQIESTKNTQQITKAMKLVSAAKLRKAQNNIVNMRPYALALRQVIADIAVTNKVSHPLMEKKEQVKNVLLVVITSDRGLCGAFNSNINKFAEAYYNSNKASLEKIDFLFVGRRGHDYFARRGIKAVDYITKLDKDISYELASKVANRVMNDYLEGSYDEVRIVHNEFKSAISQVVTAETLLPIDLGMTTFKKEADTASNFAVDMIFEPAPEQIIKELLEKHFELQVYRCMSESVAGEHGARMSAMENATNNAKEMINKLTLTYNKLRQEKITTELIEIVSGAEALKG",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPNIDFVGKRSFFIYLSIALILFSVIVIFVKGFNLGVDFSGGSEIIVSFDKSYTIDELRNGLQTINQEYATAKIIQTNPGGGASDQFFYIITVRDSFPTLEEKQMFINSLEESFSDSSLNIEQFNDVSGYAAREIRSYAWYAVIISLIVLLAYITIRFQFSYGVGAILALAHDVIITLGFYSLFGIEMNLTAIAAFLTLAGYSLNDTIVVYDRIRENRSKNRGMDIESITNKSINEVIVRSLNTSLTTFLVVFMMFLLGGRSIASFAFGLTVGVIIGTYSSLYIASPIVIGMVKRRKKTQKA",
    "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKIRSPIVSVLGHVDHGKTTLLDYIRGSTIAAKEAGGITQHIGATEIPNDTIENICGDFISKLAIKDLIPGLFFIDTPGHAAFTSLRKRGGALADLAVLILDVNDGFKPQTYEALNILKMYKTPFIVVANKIDRLFGWEVHEGASFRETFSNQAKSVQQDLDNKIYEIVGELHKEGFQSERFDRVSNFASQISIIPISAKTGEGVIEVLAMLLGLAQEYLTEQLEIDENAPAKGTVLEIKEETGLGVTLDAIIYDGVLRTNDEIALMLSSEDVLVTKIRSILRPLPLEEMRDSKKKFRKLDEVVAAAGIKVAAPHLDDVVSGSPLRVLSEDTDVEQEILNEIDNITIDTEDEGILVKADTIGSLEAVVKLLREMDIPIRAADIGDVNRRDIINSSIAYDENELHGAIIAFNVDVHPNSEEDLNNSEVKLFSGDVIYQILEEYEEWVKQKQEDKKKSFYDAIIKPAKFVSLPKLVFRQSKPAIIGIESLSGTLKQGQQLINKDGHVVGSIASMEDKGETLPDISRGQRVAMAIKDAIVGKDFEEGDELYVDIPEKHYKYIEREFKDKLTEDEFETLYEFLEIKRKQDSDWGSFGLFE",
    "output": "Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLCCMRRTKQVEKNDDDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKESARQDEGKEEEPEADQEHA",
    "output": "This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQISKFFKFVFISVSLCGSLLFPQMANAYPVFAQQAYDNPREATGRIVCANCHLAQKPTEVEVPQAVLPDTVFEAVVNIPYDTKVQQVTASGTPGPLNVGAVVILPEGFKLAPKGRMSDELKAKTKGVFVQPYSKTRPNILVVGPILGEKNREVTFPILAPDPAQDKSVHYLNYPIYVGANRGRGQVYPSGEKSNNNTFTSTAAGKVTAIEAGDKGTTRVTIQTAAGEAKEQTVPAGLKVSVKTGDVIQADQALSYNPNVGGFGQAETEVILQSPNRVKGMIAFFFTVTVAQILLVLKKKQFEKVQAAEMNF",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALQRTFSIIKPDAVAKNVIGEITTRFEKAGLRVVASKMVQLSEREAAGFYAEHSERGFFKDLVAFMTSGPVIVQVLEGENAVAKNRELMGATNPKEAAPGTIRADFAVSIDENAVHGSDSEASAAREIAYFFAATEVCARIR",
    "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSVIDTNQIDLVAPRISEAGVADYIALLKPRVMSLVVFTALVGMLLAPGDFHPVLAITAMLCIAVGGGAAGALNMWYEDDIDGQMTRTANRPIPRGRVTRPEALTFGITLSFFSVMTLGILVNWVAGALLAFTIFFYVVIYTMWLKRSTAQNIVIGGAAGALPPVVAWAAVTGSLAVEPLLLFAIIFFWTPPHFWALALFRNDDYARAGVPMLPVVAGQDHTRLQILLYTIVLVAVAAAPWPLGYFSAIYGVASLALGGWMLVLALRVYRHRTGSAALRATRNLFKFSILYLFALFSILLLEVVAKAVWRLFA",
    "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPVEEPLATLSSIPDSSADQAPPLIADEFTLDLPRIPSLELPLNVSTKHSSIQKAIKMCGGIEKVKEAFKEHGPIESQHGLQLYLNDDTDSDGSKSYFNEHPVIGKRVPFRDESVILKVTMPKGTLSKNNNSVKDSIKSLKDSNKLRVTPVSIVDNTIKFREMSDFQIKLDNVPSAREFKSSFGSLEWNNFKSFVNSVPDNDSQPQENIGNLILDRSVKIPSTDFQLPPPPKLSMVGFPLLYKYKANPFAKKKKNGVTEVKGTYIKNYQLFVHDLSDKTVIPSQAHEQVLYDFEVAKKTKVYPGTKSDSKFYESLEECLKILRELFARRPIWVKRHLDGIVPKKIHHTMKIALALISYRFTMGPWRNTYIKFGIDPRSSVEYAQYQTEYFKIERKLLSSPIVKKNVPKPPPLVFESDTPGGIDSRFKFDGKRIPWYLMLQIDLLIGEPNIAEVFHNVEYLDKANELTGWFKELDLVKIRRIVKYELGCMVQGNYEYNKYKLKYFKTMLFVKESMVPENKNSEEGMGVNTNKDADGDINMDAGSQMSSNAIEEDKGIAAGDDFDDNGAITEEPDDAALENEEMDTDQNLKVPASIDDDVDDVDADEEEQESFDVKTASFQDIINKIAKLDPKTAETMKSELKGFVDEVDL",
    "output": "TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauA domain of TFIIIC that binds boxA DNA promoter sites of tRNA and similar genes. Participates in the interconnection of tauA with tauB via its contacts with TFC3 and TFC6. Serves as a scaffold critical for tauA-DNA spatial configuration and tauB-DNA stability."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEAPICLVENWKNQLTVNLEAIRILEQIAQPLVVVAIVGLYRTGKSYLMNRLAGRNHGFSLGSTVQSETKGIWMWCVPHPTKPTHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLSSTFVYNSMSTINQQALEQLHFVTELTQLIRAKSSPREDKVKDSSEFVGFFPDFIWAVRDFALELKLNGRPITEDEYLENALKLIQGDNLKVQQSNMTRECIRYFFPVRKCFVFDRPTSDKRLLLQIENVPENQLERNFQVESEKFCSYIFTNGKTKTLRGGVIVTGNRLGTLVQTYVNAINSGTVPCLENAVTTLAQRENSIAVQKAADHYSEQMAQRMRLPTDTLQELLTVHAACEKEAIAVFMEHSFKDDEQEFQKKLVVTIEERKEEFIRQNEAASIRHCQAELERLSESLRKSISCGAFSVPGGHSLYLEARKKIELGYQQVLRKGVKAKEVLKSFLQSQAIMEDSILQSDKALTDGERAIAAERTKKEVAEKELELLRQRQKEQEQVMEAQERSFRENIAKLQEKMESEKEMLLREQEKMLEHKLKVQEELLIEGFREKSDMLKNEISHLREEMERTRRKPSLFGQILDTIGNAFIMILPGAGKLFGVGLKFLGSLSS",
    "output": "Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens . Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product . Following infection, recruited to the pathogen-containing vacuoles or vacuole-escaped bacteria and acts as a positive regulator of inflammasome assembly by promoting the release of inflammasome ligands from bacteria . Acts by promoting lysis of pathogen-containing vacuoles, releasing pathogens into the cytosol . Following pathogen release in the cytosol, promotes recruitment of proteins that mediate bacterial cytolysis, such as Gm12250/Irgb10: this liberates ligands that are detected by inflammasomes, such as lipopolysaccharide (LPS) that activates the non-canonical CASP4/CASP11 inflammasome or double-stranded DNA (dsDNA) that activates the AIM2 inflammasome . May play a role in erythroid differentiation ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTQRVFQVWKGSNKFILGGRLIFGPDARSLPLTLLLIIVPVVLFCVFVARHLRHEFSPYNAGYAIMVVAILFTIYVLILLFFTSARDPGIVPRNSHPPEEDLRYETTVSADGRQTPSVQIPRTKEVIVNGVSVRVKYCDTCMLYRPPRCSHCSICNNCVERFDHHCPWVGQCIGLRNYRYFFMFVSSSTLLCIYIFSMSAVYIKILMDHQQATVWRAMKESPWAVVLMIYCFIALWFVGGLTAFHLYLISTNQTTYEKLRYRSSHSRSIVYNRGCPNNFLEVFCSKVKPSRNNFRAFIEEEPPRVITLPSTTRESGEAEDENVTRRQKVEDDLDIGDDLMNLSRRCNAEDANNNQPHHTLDIDHERAGSIRTEARHESWGRRSGSWDVAATDVRESRSYATAKDGRG",
    "output": "S-acyltransferase involved in protein lipid modification."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRLWKSMAWGILLWHSQSGALCPAWPPARAAEEITRLQQQLADWNDIYWKQGVSAVDDSVYDQLSARLVQWQRCVGQDVSSTPVSPPLNGTTMHPVAHTGVRKLADRQAVEQWMRGRSELWVQPKVDGVAVTLVYQNGKLTRAISRGNGLQGEDWTPKIRLIPSIPQTTQGALANAVLQGEIFLQREGHIQQRMGGMNARSKVAGMLMRQDNASALNSLGIFIWAWPDGPANMPERLSQLAKAGFSLTNKYTLAVKDASEVERARQSWLTSALPFVTDGVVIRMAKEPASQHWRPGQGDWLAAWKYPPVAQVAQVSAIQFSVGKSGKITVVASLVPVILDDKRVQRVNIDSVKRWEAWDIAPGDQILVSLAGQGIPRLDEVVWRSRERSKPVPPDSHFNSLTCFYASETCQEQFISRLVWLGSRSALGLDGMGEASWRALHQTHRFKHIFSWLALTSAQIANTPGFAKGKSEQIWRQFNLARRQSFTRWIMAMDIPLTQAALQASGDRSWEQLLMRTEQHWWQLPATGERRAGRVIDWRNNPQIKTLSRWLAAQHIPGFGS",
    "output": "Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFARTFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIKDTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKIL",
    "output": "Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDIRAAEISAILKEQIKNFGKEAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFPGGIRGMALNLESDNVGVVIFGADRDIKEGDVVKRTGAIVDVPVGPELLGRVVDALGNPIDGKGPIKAKERRRVDVKAPGIIPRKSVHEPMSTGLKAIDALIPVGRGQRELVIGDRQTGKTAIILDTFLNQKPIHDNGPDKDKLYCVYVAVGQKRSTVAQFVKVLEERGALEYSIVVAATASDPAPMQYLAPFAGCAMGEYFRDNGQHALIGYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDENGAGSLTALPVIETQGNDVSAFIPTNVISITDGQIFLETNLFYQGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKGELAQYREMAAFAQFGSDLDAATQRLLNRGARLTELLKQPQFSPLKTEEQVAVIYAGVNGYLDKLAVNQVGKFEEGLLASLRTEHKDVLEGIRNEKALTDDLKAKLKAAIDAFAKSFA",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTVGLLGGSFDPPHEGHVQISRAALKRFDLDQLWWLVTPGNPLKENPPASMTRRIKAAREIMDHPRVRISDIEARLNTRYTAQTLRELRKLYPQVRFVWLMGADNLAHFHRWKNWRGIMESVPVGVLARPGDRISARLSRAARIYSQHRIPAGQSHLLARASSPAWCFLNVPMTKASSTEIRKRGAWTG",
    "output": "Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLTLTPVLTVSYEAKISFLFLSVVEFAVGIMANAFIVLVNFWDMVKKQPLNNCDIALLCLSITRLFLQGLLLLDAIQLACFQQMKDPLSHNYQAILTLWMSANQVSLWLAACLSLLYCAKIVRFSHTFPLHLASWVSRRFLQMLLVALLFSGVCTALCLWDFFSRSHTVVTSMLHMNNTEFNLQIEKLNFFYSFVFCNVGSVPPSLVFLISSGVLVISLGNHMRTMKSQTRGSRDPSLEAHVRAIIFLVSFLCFYVVSFCAALISIPLLVLWHNKGGVMVCIGMMAACPSGHAAILISGNAKLKKVIVTILFWFQSRQKVRRVHKVLPRIL",
    "output": "Putative taste receptor which may play a role in the perception of bitterness."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNLTHINEEGRARMVDVSEKAETKREAVAIGSIYMKNETLRRIHEGTIKKGDVLAVAQVAGIMAAKNTSHMIPMCHPIMITGCDISFNLDFENSKIDIKAVVKTVGQTGVEMEALTAVTVAALTIYDMCKAIDRDMVISEIMLVKKSGGKSGLYEREV",
    "output": "Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPDLKRAIGLMSGTSMDGIDIALLATDGENWIERRASASMDYSDGFRARLKAGLVDARAIKDRAERPGLLRQLEHDLTLLHAVAVHDFLHEQGLQPHEIDVIGFHGQTVLHRPNESLTVQIGDGALLARETGIPVVYDMRAEDMRHGGQGAPLIPAYHAALAANLPLGLKGPVVFVNIGGISNLTYVGEDGALIAYDSGPGNMLIDQWMELHGHGRFDPGGATAMSGSVDRNTAHRYLEHEFFKGNHRRSLDRGDFAIPAKGELNLADGARTLAFVSAAAILKSASHLPARPRTYVVSGGGRKNGALMDELTALAEREGAHVIDADNAGFDGDAMEAEAWAYLAVRSLCGLPLTYPSTTGCDKPVSGGVPVRP",
    "output": "Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSYAIIETGGKQVRVEPGRFYDIERLDVDVDGNHTIEKVLLISDDNGVTVGQPYIDGATVEGTVVDQRRAKKVLVYKMLPKKKTRKKRGHRQYFTRFMIDSIKVGGNVVAAKADA",
    "output": "This protein binds to 23S rRNA in the presence of protein L20."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGRGRVELKRIENKINRQVTFSKRRNGLLKKAYELSVLCDAEVALIIFSSRGKLYEFGSAGINKTLEKYNSCCYNAQGSNSALAGGEHQSWYQEMSRLKTKLECLQRSQRHMLGEDLGPLSIKELQQLEKQLEYSLSQARQRKTQIMMEQVDDLRRKERQLGELNKQLKNKLEAEADSSNCRSAIQDSWVHGTVVSGGRVLNAQPPPDIDCEPTLQIGYYQFVRPEAANPRSNGGGGDQNNNFVMGWPL",
    "output": "Probable transcription factor. Plays minor but redundant roles with MADS6 in floral development."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQDVINSEKLKFDAEVGKVLKLVIHSLYTNKDIFLRELVSNASDACDKLRYESLSNQDLIDQDSDFKIVISVDQDKNRLYISDNGIGMNRQDLIDNLGTIAHSGTQRFLDEINNGTSSQGVVELIGKFGVGFYSAFMVASEVIVESRKAGESIGYQWKSHGDGEFTISQLEDNQISRGTKITLILKPEESEFTDRFRIEHIITTYSYHINYPVYFLNDKGEEEKLNSDAAIWTKSKGEISAEEHQNFFRTVAHVGGEPWMILHNKNEGVVEYTNLLYIPSIKPFDLFHPDRKCSVKLYVNKVFITEDNVQIIPQYLRFLKGIIDSSDLPLNISRETLQNNKIIEKIKQSIVNRVLSELKKKAESDIKDYKKFWENFGSVLKEGLCESMNTEFREELMSACRFYSTYSDDSLISLEDYIERMKAGQDNIYYLTGNDLDSVKKSPQLEGFISRGIEVILLVDPVDDFWTNVVTDYQKVPLKSVIRADEDLEKLAHLDKSEEIKENEDESVDSKEKVDTFVKYAAQVLDKLVSSVRVSKKLTNSPVCLAVADGSMDIRMERFLREQKQLNYKSTKILEINPKHPIVTKMIDEHANAGESVTLENMLHLLLNQACILEGEELQDVSDFAERMNNILAKVYQ",
    "output": "Molecular chaperone. Has ATPase activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MALQGWVQRGWRCGPAWAPPLGGGYRELSATQAPRLLGRRFNLFVQQKCGFRKAPRKVEPRRSDTGSSGEAYKRSALIPPLEETVFYPSPYPIRTLVKPFFFTIGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGNLRKEINKWWNSLSDGQRTVTGIIAANALVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFVAVYLSAGVISNFVSYVCKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPVFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYITYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK",
    "output": "Required for the control of apoptosis during postnatal growth . Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptotic signals . Required for the maturation of PINK1 into its 52kDa mature form after its cleavage by mitochondrial-processing peptidase (MPP) (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain (By similarity). Required for processing of CLPB into a form with higher protein disaggregase activity by removing an autoinhibitory N-terminal peptide."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQKIRRDDEIIVIAGKDKGKRGKVLKVLADDRLVIGGVNLVKRHTKPNPMAGVQGGIVEKEAPLHASNVAIFNGETNKADRVGFKVEDGKKIRVFKSTQKAVDA",
    "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "WYSSMFAANIKQEPISHHHHHHHAHHSHHAHDSNSNSNASSPHQSPLPSPNPPSHTNLQLEQYLKQQQQQQQQHQHQQQQQPMDTLCAAAMTPSPSNNDQNSLGWLVGLPNPMQTIMPANMRPSPTATTATAAAAAPTTTAAAIALQANDKLQALTPPMDVTPPKSPAKSQQSCAEPEKEHDLMSNSSEDMKYMA",
    "output": "Gap class segmentation protein that controls development of head structures."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAAVSVYERPVGGFSFDNCRRNAILEADFAKKGYKLPTARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPEMEEEEAKQLVSEAIAAGIFNDLGSGSNIDLCVISKSKLDFLRPYSVPNKKGTRFGRYRCEKGTTAVLTEKVTALDIEVLEETVQTMDTS",
    "output": "Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAFPGPRVLVVGSGIAGLGAAQKLCSHRAAPHLRVLEATASAGGRIRSERCFGGVVELGAHWIHGPSQDNPVFQLAAEFGLLGEKELSEENQLVDTGGHVALPSMIWSSSGTSVSLELMTEMARLFYGLIERTREFLNESETPMASVGEFLKKEISQQVASWTEDDEDTRKRKLAILNTFFNIECCVSGTHSMDLVALAPFGEYTVLPGLDCILAGGYQGLTDRILASLPKDTVAFDKPVKTIHWNGSFQEAAFPGETFPVLVECEDGARLPAHHVIVTVPLGFLKEHQDTFFEPPLPAKKAEAIKKLGFGTNNKIFLEFEEPFWEPDCQFIQVVWEDTSPLQDTALSLQDTWFKKLIGFLVQPSFESSHVLCGFIAGLESEFMETLSDEEVLLSLTQVLRRVTGNPQLPAAKSVRRSQWHSAPYTRGSYSYVAVGSTGDDLDLMAQPLPEDGTGTQLQVLFAGEATHRTFYSTTHGALLSGWREADRLVSLWDSQVEQSRPRL",
    "output": "Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion . Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDLISFKEKDISKKECLELFLDTENFFDILKVADDIRKESVGDTVTYVLNANINFTNVCSGTCKFCAFKTEKEDPNSFFLNPDKVAEKALLARKTGATEVCIQGGLLPEIDTYFQAEILQKVKKITEKYGGIDIHAFSPMEVKSAAENCGLNVKEALKILKDSGLKTMPGTAAEILNDEIRNEICPTKLTTSEWIDVVKTAHKNGIKTTCTMMYGHIEENVHLVEHLSILKEIQKETSGFTEFVPLTFLHENAPLHHIGKVKSGASGILDLKVYAISRIFFKNYLKNIQTSWVKLGIKLSQISLNCGANDVGGTLMEESISKAAGGSFGTCMSEEKLKNMILNVNKIPKKRNTLYELIN",
    "output": "Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLTFIELLIGVVVIVGVARYIIKGYSATGVLFVGGLLLLIISAIMGHKVLPSSQASTGYSATDIVEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAICASPAAIILAPTSGDVVLAAQASEMSLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKEHISHEMLDVSEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVICMLIASILEFLRSFNTQKVFSGLEVAYRGMADAFANVVMLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAVTTGSGNAPFYAFVEMIPKLAHSSGINPAYLTIPMLQASNLGRTLSPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLVIVIVATELMVPGTAAAVTGK",
    "output": "Responsible for the transport of C4-dicarboxylates during anaerobic growth. Catalyzes the uptake of fumarate coupled to the export of succinate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNLGTLVSETRNPQTMDLDALPTPELVKRFNEQDTLVAEAVKATLPDVARAVDAAAAALKSGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDCQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCTTVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACRMVVEATGIGREEAEALLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH",
    "output": "Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTEKKNRREKKNPREAKITFEGLVMEALPNGMFRVRLENDTIILGYISGKIRSSSIRILMGDRVKIEVSRYDSSKGRIIYRLPHKDSKRTEDSKDTEDLKDTKDSKG",
    "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MASVSELACIYSALILHDDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANIDIGSLICNVGAGGGAPAAAAPAGGAAPAGGGAAPAEEKKEEEKKEESEESDDDMGFGLFD",
    "output": "Plays an important role in the elongation step of protein synthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFSKSGMSDLMKHAQRMQEQMQQMQGEIAKLEVNGESGAGLVKVTINGVYHCRRVEIDSSLLQDDKDMLEDLITAAFNDAVRRITEIKKDKMTSLSSSLQMPLGFNWNMPFL",
    "output": "Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTNSSLRPSGRRADQLRDVRITRHYTKHAEGAVLVEFGDTKVICTASVAERVPEFLRERGQGWLTAEYGMLPRATHTRSDREAARGKQTGRTQEIQRLIGRALRAVFDLNALGPRTLHLDCDVIQADGGTRTASITGAFVAAHDAVTKLVAAGRIARSPITDYVAAISVGVFGGTPVLDLDYDEDSACDTDMNVVMTGAGGFVEVQGTAEGAPFSRTEMNALLDLAQAGIGELVRLQRAALEA",
    "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAAAGDVILEDVPGSVNLFNTLQDQITKVTAHVQDLTQKVRSGIYNTDKGLSFLELKDQLLLFYLQDLTHLMLEKTNGKSIKGNPGILRLVELRTVLEKMRPIDQKLKYQIDKLVKAAVTGSLGENDPLRFKPNPQNLMSKLSEPDERESDSGEEGAEGGVAKKPQSKVKRYIPPRLAPVHYDDTEAEREHRIVERAKKLALSSSTIRELKEQYSDAPEEIREGRAYHMMRHDKEEQHRINHEESMMVRLNMTRKEKARKKRVLSMTSQLNSLTHFSDISALTGGEGRAEDMVPSMKKSKKGPKKSKKKKGFSRRRH",
    "output": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Its dissociation from the complex determines the transition from state pre-A1 to state pre-A1* (By similarity). May inhibit mRNA translation (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSGAASGTGRGRPRGGGPGPGDPPPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLESQRQVPRSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVRAVRKYQEQELPPSPPSAPRKKGGGCPCVLL",
    "output": "Regulates the organization of the actin cytoskeleton . With OSPBL3, modulates integrin beta-1 (ITGB1) activity ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGRMTATPARRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPIYVRHEIVHNKYVVQTLEKKGAIFVDVTAEVPEGSIVMFSAHGVAPTVHAEAAERKLATIDATCPLVTKVHKEAVRYAKDDYDILLIGHEGHEEVIGTSGEAPDHIQLVDGPEDVANVEVRDESKVVWLSQTTLSVDETMETVDALKSKFPNLLSPPSDDICYATQNRQIAVKKLAEDAELVIVVGSKNSSNSIRMVEVALDAGAPAAHLVDFASEIDEAWLEGVTTVGLTSGASVPDVLVDGVLEWLGERGYADVETVKTADESITFSLPKELRRDLRAEAAALSAE",
    "output": "Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPGFTCCVPGCYSNSHRDKGLHFYTFPKDPELRCLWLKNVSRGGVSGCFSTFQPTNGHRVCSLHFQGGRKSYSIKVPTIFPLRGVNEKRTRRSSTKKRQQPNYTPAATTVLVTGLPGQEEQEVLELTAGGAEMMLLGTTAGMGAAIADVEGSSAVMGATIDAMATAAEGGSAAASNIAVKLDVGETHAVNTHFSTDASHGSHQQLQVVVVGDEPYPSADCWPSPLCSDHSYSMSSGTTTEELLRKLNEQRDIIALMEVKMKEMKSSIKHLKVTEVKLREELRQKDKDKVSPMIKSN",
    "output": "Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKTELKAVLKRPKISEKFDELREKKEGALIGYVMAGDPTFEASSEVVKALAKGGADIIELGFPFSDPVADGPTIQVAGQRALAEGMDIERYFAFARALEVDVPLVCMTYYNPVFRYGVEKFVENAAEAGISGLIIPDIPVEEAADLKTGCDAHGLDLIFLVAPTTTEARIRKILQRGSGFIYLVSRLGVTGARDDVAGSTKELLSRVNTDIPKAVGFGISTGEQAAEVRKAGADGVIVGSAFVRIIEEGTDVNERLETLARELKSGMLEAN",
    "output": "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTDAKMKKKRTTPFLYLASIVFLPWWISLFFKKSLESWVTNWLNISQSEPFLNDIQEKSLIEKFIELEELLLLDEMIKECPKLDLQKFRIGIHKETIQLMNMYNDDRIHTILHFSTNIISFVILSVCSILGNEELVILNSWIKEFLYNLSDTLKAFCLLALTDFLFGFHTISAWELLIGSVVHNDQMRSLLVCLFPSVLHTIYYFWTFNYLNCVSPSLVVLYDSLVDVD",
    "output": "May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake into chloroplasts."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTRNYENKEGQRVYVTEVVADSIQFLEPKNSNDTQQDLYQQQVQQTRGQSQYSNNKPVKDNPFANANGPIELNDDDLPF",
    "output": "Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MADINAYEGPAEAGFGDYVALLKPRVMSLVVFTAFVGLWIAPQPVNPFVAFCAVLFIALGGGASGALNMWYDADIDAVMRRTAGRPVPSGRVTSQEALAVGIALSGLSVMMLGLAANWFAAGFLAFTIFFYAVVYTIWLKRSTPQNIVIGGAAGAFPPMIGWACATGGIGIESLLMFALIFFWTPPHFWALALFMKDDYSKAGVPMLTVTHGRKVTRCHIFAYTLVLAPFALWLGFTSVGGPLYLAVSVVLNALFIAGGWQILRRSEDQAQADGYRVEKRYFRLSLYYTFLHFLALLVQHWVGGW",
    "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVEYYEVLGVQRNASADDIKKAYRRLALKWHPDKNPDNKDEAERRFKEVAEAYEVLSDSKKRDIYDKYGKEGLTNRGGGSHFDEAPFQFGFTFRSPDDVFRDFFGGRDPFSFDLFADDPFDDFFGRSRHRANRSRPAGGGGGPFLSTFGGFPAFGPSFSPFDSGFSSSFGSFGGHGGHGGFTSFSSSSFGGSEMGNFRSVSTSTKVVNGRRVTTKRIVENGQERVEVEEDGQLKSLTVNGKEQLLRLDNK",
    "output": "Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Also reduces cellular toxicity and caspase-3 activity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDDLANLVFPGQQVAVTWDGSSSTEALKEFVSKLQEVVAPRGKVSVENIERLLLSAHADSSFDAILLGMVQGTQCIHSSEVLAEVARILKPGGALIIQEPVAAGAGAQLRTPEHLSSVLKLSGLTEVTQLLQEPLNPEQKQGVVELLGYNGNDVSTIRIRAKKPNYEVGSSRQLSLPKRKTAEKPSVDPAAAKLWTLSASDMNDDDVDILDSDELLDQEDLKKPAPSSLLASGCGEGSEKKRKACKNCTCGLAEELEAEKTPSTVPKAAPSACGNCYLGDAFRCASCPYLGMPAFKPGEKVLLNPTKLQDA",
    "output": "Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATSQRKILVTSALPYANGPIHLGHMLEYIQTDIWSRYQKLRGHECHYICADDAHGTPIMLKAQQLGLAPEEMIAQVNKEHQQDFADFNIAFDNYHSTHSDENRVLASDIYLKLRTNGYIKSKSISQLFDPEKSMFLPDRFVKGTCPKCKSPDQYGDNCDACGATYSPTELINPKSAVSGATPVMKDTEHFFFDLPAFEGMLKEWTRSGALQTEMANKLDEWFEQGLQQWDITRDAPYFGFEIPDAPGKYFYVWLDAPIGYMGSFKNLCDKRPELSFDEFWAKDSKAEVYHFIGKDIVYFHSLFWPAMLHGSGYRQPNSVYAHGYVTVNGAKMSKSKGTFIKARTYLDHLDPEYLRYYYAAKLSSRIDDLDLNLEDFAQRVNSDLVGKLVNLASRTAGFITKRFDGKLAKIADTTLTEAFLAKQEQIAEFYETREYGKAMREIMALADIANGFVADAAPWQMVKQDDQQEAAHQVCSNALNLFRILVTYLKPVLPRLAQDVEAFFQQTLTWDGLAQDMAGHEISPFKAMMQRVELDKVNAMVADSKENLQVTADVPKTAKPEKTVESSNVSSEPLVDDPISETINFDDFAKIDLRIARIVKAEHVAEADKLLKLQLDIGGETRQVFAGIKSAYSPEDLEGKLTVMVANLAPRKMRFGMSEGMVLAAGPGGSDLWILEPHEGAQPGMRVK",
    "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIWHVQNENLILDSTRIFMKAFHLPLFDGSFIFPEGILIFGLILLLMIDSTSDQTDIPWFYFISSISLVMSITALLFRWREEPRILFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHPLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDANGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLFTSVVSIYYYLKIIKLLMTGRKQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGGHLSPWPTYTSGQTILQNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGSGLLREKDFFPGLGYGEAIPAFLRFDGLVENKKPSKKDVVNLLKDAWKERLAEEQKETFPDFFFNFLEHRFGPSDAMAWAYTIFENIKIFHSNEVMSQFYAVLMGKRSENVYVTQKETVAQLLKEMTNADSQNEGLLTMEQFNTVLKSTFPLKTEEQIQELMEAGGWHPSSSNADLLNYRSLFMEDEEGQSEPFVQKLWEQYMDEKDEYLQQLKQELGIELHEEVTLPKLRGGLMTIDPSLDKQTVNTYMSQAFQLPESEMPEEGDEKEEAVVEILQTALERLQVIDIRRVGPREPEPAS",
    "output": "Possible role in spermatogenesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MWGAFLLYVSMKMGGTAGQSLEQPSEVTAVEGAIVQINCTYQTSGFYGLSWYQQHDGGAPTFLSYNALDGLEETGRFSSFLSRSDSYGYLLLQELQMKDSASYFCAVR",
    "output": "V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens . Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation . The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKPQSDADRRKQISVRGIAEVGNVTEVKKNFNRHLHYTLVKDRNVSTLRDYYFALANTVKDNMVGRWIRTQQHYYEKDPKRVYYLSLEYYMGRSLTNTMINLGIQSECEEAMYQLGLDIENLEEMEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFAQKIKNGEQVEEPDDWLRYGNPWEKARPEFMLPVNFYGRVIDTPEGKKWVDTQRVFAMPYDNPIPGYNNNHVNTLRLWSAKSPIDFNLKFFNDGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFMCAATLQDIIRRYKASKFGSREAVRNTFDHFPDKVAIQLNDTHPSLAIPELMRILVDEEHLTWEKAWDITVRSCAYTNHTVLPEALERWPVSLLESILPRHLQIIYHINFLHMENVKKKFPDDLDRMRRMSMVEEDGEKRINMAHLSIVGSHAVNGVAAIHSQILKDSLFHDFYEMEPQKFQNKTNGITPRRWLLLCNPGLSDLIAEKIGDEWPVHLDQLVALKKWAKDPNFQRNVARVKQENKLKLAAILEKDYGVKINPSSMFDIQVKRIHEYKRQLLNCLHIITLYNRIKKDPTANFTPRTIMIGGKAAPGYYVAKQIIKLICAVGNVVNNDPIVGDKLKVIFLENYRVTLAEKIMPAADLSEQISTAGTEASGTGNMKFQLNGALTIGTLDGANVEMAEEMGLDNIFIFGMTVDEVEALKKKGYNAYDYYNANPEVKQVIDQIQGGFFSPGNPNEFKNIADILLKYDHYYLLADYDAYIKAQDLVSKTYQNQAKWLEMSINNIASSGKFSSDRTIAEYAREIWGVEPTWEKLPAPEDQPQN",
    "output": "Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). Required for glycogen breakdown in skeletal muscle."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASYVAAIDQGTTSTRCMIFNHSGRVVAVDQVEHRQIFPRAGWVEHDPEEIWSNTRQVCAGALAKADLVTSEIAAVGITNQRETTVVWDRKTGKPVYNAIVWQDTRTDSIVNELAADGGQNRYHRKTGLPLATYFSGTKIRWILDNVDGVRARAEKGELLFGNMDTWVLWNSTGGPDGGLHVTDPTNASRTLLMDLETLDWDTDICAEFGIPTSMLPEIRSSSEVYGHFRERGVFGGLPIAGILGDQQAATFGQACLSPGEAKNTYGTGNFLLLNTGTERVLSENGLLTTVGYKIGGNDTVYCLEGSIAVTGSLVQWLRDNLGLIASAPEIEQLARTVDDNGGAYFVPAFSGLFAPHWRSDARGAIVGLTRFVDRGHLARAVLEATAFQTREVIEAMNADSGVPLKSLKVDGGMVGNELLMQFQADILGVPVIRPVVSETTALGAAYAAGLAVGFWGSEEDIRSNWAKDKQWDPLMPEEKREAEYRQWQKAVTKTFDWVE",
    "output": "Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSEELQPVFSIERLYVKDLSLEVPHAPQIFLEQGDPEVDMRVSTGSQKLEDGYYDVDVTVTVTAKLDNERTMFLNEVTQSGIFRLENIPEEDVQLLLGVACPNILFPYAREAVSGTVTRAGFPPVLLAPINFEAIYQQQQEAEAAGA",
    "output": "One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTHVEIRHAMDPVSARQLDTAGLREAFHMGDLFRSGEIRLVYTHYDRMIVGGAVPAGEPLVLDEVKPTGTASILDRREMGVVNVGAAGTVSAGGESWEMGRGDVLYLPMGAGPVTFAGEGRFYILSAPAHTAHPARLVKLEDAKKVKLGSPETANERTINQFIHPEVMQSCQLVVGYTQFHGGSVWNTMPAHVHDRRMEAYLYFDLAEEARVFHFMGEPSETRHLVMRNEEAVVSPPWSIHCGCGTGSYTFVWAMAGDNVDYRDVEMVAMEDLR",
    "output": "Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHIKKGDKVIVITGKDKGKTGTVIEALPKRDRVVVEGVNIVKKHQKPTQMNPEGGITEFEAAIHVSNVMLLDPKTNKPTRVGTKIEDGKKVRVAKKSGEIIK",
    "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFNNNSNNGNSNGNRGYNNNNRNNERSQGYNQNIEQQLASQEKKTAYRRTVDHGNNMGRWYINRSLGIDDQPIGKIRPESSYLIDLLPSPAYASNSVRENKNNMSIMDIQTKFVHLSSNKAKHSINTVKWTPEGRRLLVASHSGEFTVWNGMTFNFETIMQAHDSAILSLKYSHNDEWLLSGDQSGVIKYWQTNFNNVNIINGHSDGIRDIAFSPNDSKFLTCSDDSTMKIWNFNNGQEERSLVGHHWDVKSADWHPNLGLIVSGSKDNLIKLWDPRASSCVSTLHGFKHTITKTKFQPTGTKRLLASVSRDKSCRIFDLRTMKDILVIRDHETDLSCVEWHPVHPSMITTAAYDGSMNHYIMDSYISDNNIKNDSNNNSTSPIEASHKIPYAHEKAIHALEYHPLGHLLCSAGADRSARFWSRARPNDPMSFQDALYTNDKVGAWYYGVNNNINAVIEPSTASVNKDDPSSAQAINLPGLNNLPNGNESTTNGWGNIPGLRGH",
    "output": "Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLPSDLVKYKKNSQKIIALTAWDSISGSIAEQANVDLVLVGDSLAMVCLGYKSTLPLTLGNIIYHTNAVSRGFKKNIEEQPLVIADMPFLTYQCGEDKAVEYAGKIIQSTYAKAVKIEGAEPEIQKVISRLIRMGIPVMGHIGLTPQSYLNLGLKKQGESLESQEKIKKEASILEKLGCFSIVLEHIPDLLAKEIQNTLTIPTIGIGAGNYCDGQVRVTADLLGLNDDQPPFCQPIIQGKELFMKKLKEWVESERLN",
    "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFDTVLVANRGEIAVRVIRTLRRLGIRSVAVYSDPDVDARHVLEADAAVRLGPAPARESYLDIGKVLDAAARTGAQAIHPGYGFLAENADFAAACERARVVFLGPPARAIEVMGDKIAAKNAVAAFDVPVVPGVARAGLTDDALVTAAAEVGYPVLIKPSAGGGGKGMRLVQDPARLPEALVSARREAMSSFGDDTLFLERFVLRPRHIEVQVLADAHGNVVHLGERECSLQRRHQKVIEEAPSPLLDPQTRERIGVAACNTARCVDYVGAGTVEFIVSAQRPDEFFFMEMNTRLQVEHPVTEAITGLDLVEWQLRVGAGEKLGFAQNDIELRGHAIEARVYAEDPAREFLPTGGRVLAVFEPAGPGVRVDSSLLGGTVVGSDYDPLLTKVIAHGADREEALDRLDQALARTAVLGVQTNVEFLRFLLADERVRVGDLDTAVLDERSADFTARPAPDDVLAAGGLYRQWALARRAQGDLWAAPSGWRGGGHMAPVRTAMRTPLRSETVSVWGPPESAQVQVGDGEIDCASVQVTREQMSVTISGLRRDYRWAEADRHLWIADERGTWHLREAEEHKIHRAVGARPAEVVSPMPGSVIAVQVESGSQISAGDVVVVVEAMKMEHSLEAPVSGRVQVLVSVGDQVKVEQVLARIKD",
    "output": "Component of a biotin-dependent acyl-CoA carboxylase complex. This subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, resulting in the formation of carboxyl biotin. When associated with the beta1 subunit AccD1, is involved in branched amino-acid catabolism with methylcrotonyl coenzyme A as the substrate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTSRKYFGTDGIRGRVGQFPITPEFMLKLGWAAGMAFRKMGACRILVGKDTRISGYMFESALEAGLSAAGADVLLLGPMPTPAIAYLTRTFHAEAGIVISASHNPHYDNGIKFFSGQGTKLPDEIEMMIEELLDAPMTVAESENLGKVSRINDAAGRYIEFCKSSVPTSTDFAGLKVVIDCAHGATYKVAPNVFRELGAQVVVLSAQPDGLNINKDCGSTHMEALQAAVLAEHADMGIGFDGDGDRVLMVDHTGTIVDGDELLYIIARDLHERGRLQGGVVGTLMSNLGLELALAEQGIPFVRANVGDRYVIAELLERNWQIGGENSGHIVCFQHATTGDAIIASLQVILALRRSGVSLAEARLKLRKCPQILINVRFAGSGVDPVSHPSVKEACARVTEQMAGRGRVLLRKSGTEPLVRVMVEGEDETQVRAYAEELAKLVTEVCA",
    "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNDSEFHRLADQLWLTIEERLDYWDGDSDIDCEINGGVLTITFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGETVSFR",
    "output": "Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKIRLDKSLPGGEIAVPSSKSYTIRGLIAAAQANGQSRIISPLAADDTLASRQVLSGLGIDINTDAEAESWQLTGNTFKKPAGNLFCRESAATLRFMSAVCARLPFECRLLAGHSLMRRPMLPLIQALHQLGIEIETRGNTTVIKGGEITRSKVSLPGNISSQYVSALMLMAPACKSGLEIHLATPPASLPYLKMTKQTLESFGIKAYTSIDWQEISIPPQPYLPARYRVEGDWSSASSFLALGAIAAPLFISNLDTESFQADRIMIKFLSEMGAEVESGQNWVKVSPKPLTAIQADLTHSIDLLPALAITAACAKGQSILSGVRQARIKESNRIRAVSQGLSAMGINVTEEDDRLIIEGGMPRGAEIDSLGDHRIAMAFGALGAVTGETCISEAECVSKTYPDFWQKLESLGGKVIKDV",
    "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTVKLDFEECLKDSPRFRASVELVEAEVSELETRLEKLLKLGNGLLESGRHYLAASRAFIVGICDLAHLGPPEPMMAECLDKFTQSLSHKLDSHAELLDATQHTLQRQIQTLVKEGLRSFREAGRDFWRGAESLEAALTHNAEVPRRRAQEAEEAGAALKVARAGYRGRALDYALQINVIEDKRKFDIMEFVLRLVEAQATHFQQGHEELSQLAQYRKELGGQLHQLVLNSAREKRDMEQRHVLLKQKELGGEEPEPSLKEGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQKRYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSPSKSCLLQSDSERLMQLWVSAVQSSIATAFSQARLDDSPRGLGQGSGHLAISSAATLGPGGLTRGREPGGVGHVAAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVVINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGPPRGHPPVPPKPGLIRPKPGSFRSKPEPPSEDLQSLHPGALLFRAAGHPPSLPTMADALAHGADVNWVNGGQENATPLIQATAAVRVLNSLLACEFLLQNGANVNQVDNQGRGPLHHATILGHTGLACLFLKRGADLGVRDSEGRDPLTIAVETANADIVTLLRLAKMREADAAQGQAGDETYLDIFRDFSLMASDDPEKLSRRSHDLHTL",
    "output": "GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTIPATILDTARTQVLEQGIGLNQQQLMEVLTLPEEQIPDLMELAHQVRLKWCGEEIEVEGIISLKTGGCPEDCHFCSQSGLFESPVRSVWLDIPNLVEAAKQTAKTGATEFCIVAAVKGPDERLMTQLEEAVLAIHSEVEIEVAASIGTLNKEQVDRLAAAGVHRYNHNLETARSYFPEVVTTHTWEERRETLRLVAEAGMEVCSGGILGMGETLEQRAEFAVQLAELDPHEVPMNFLDPRPGTPFADRELMDSRDALRSIGAFRLAMPHTMLRFAGGRELTLGDKGSEQALLGGINAMIVGNYLTTLGRPMEDDLDMMDRLQLPIKVLNKVI",
    "output": "Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "GPNGKSQSIIVGPWGDRVTN",
    "output": "D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSSDQEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVADPKESFVKATVQSREGGKVTAKTEAGATVTVKEDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPELIEMLLITTNPYDYAYVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQGLNSADLLKALCYPRVKVGNEFVTKGQTVEQVYNAVGALAKAVYDKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDMSFKNKLYEQHLGKSNNFQKPKPAKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSSVKTLALLFSGPASGEAEGGPKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVTLTQEKNDLQLQVQSEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSELKTKEDEQQRLINDLTTQRARLQTESGEFSRQLDEKDALVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSARHDCDLLREQYEEEQEGKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILSEWKQKYEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKVKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALKNYRSTQAILKDTQIHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDITQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE",
    "output": "Muscle contraction."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "LSAMLEDTENWLYEELSLTQDPVV",
    "output": "Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEPLKTHNGIAAVLNRINVDTDQIIPKQFLKRIERTGYGRFAFFDWRYLDNGDPNPDFELNRPEYKGASILIAGENFGCGSSREHAPWALDDYGFKIIIAPSFADIFHQNCFKNGMLPIRLPYEAWKELAEQYEYQSLTMTVDLEKQTITDHAGRQIAFEVDPHWKEMLLNGYDEISLTLLLEEEIEQFEKQRSSWLQA",
    "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLVNFVLVGFGAALGAMLRYGISVLVKSKWKTNFPFATFFINITGSFLLGFLVSSALGPVWQLFLGTGFMGGYTTFSTFKVESMELKWKTNYRVLFSYLGCTYVFGLIAAFLGLMLGV",
    "output": "Important for reducing fluoride concentration in the cell, thus reducing its toxicity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDKRALKERLSRVGRVAVLAGGRSAERAVSLKSGAAVHAGLRNLGLLAELVDPADKSVDTLRGFDAAFIALHGRGGEDGVIQGVLEHLEIPYTGSGVMASAIGMDKVRTKQLWKGAGLPTPAFYVAGREEAELGFPVIVKPAHEGSSIGMAKADNTEELGEALVAAEKFDQDVLVEAWVNGPEYTVAVLGDEALPAIRLQTPHVFYDFEAKYQSDSTEYLCPAGLDDADEQALRTLALTAFRVAGCRGWGRVDVMRDEQGQWQLLEVNTVPGMTDHSLVPMAAKATGRDFDVLVGEILLDALERGRG",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKGLIGRKIGMTRIFTDEGISIPITIIQVEPNIITQVKSIQTDGYYAYQVTTGTKKPNLVIKPEAGHFAKAGTKAGRSLWEFRLKHEEKPINIGEILTLEYFTNIKKVDITGTSKGKGFSGTVKRWNFHMQDASHGNSLSHRVTGSIGQNQTPGKVFKGKKMAGHMGNKRVTIQNLDIIRIDLRKNLLLIKGAIPGAPGNDLIIKPAIKLSH",
    "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTLEEVRGQDTVPESTARMQGAGKALHELLLSAHGQGCLTAGVYESAKVLNVDPDNVTFCVLAADEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGADEEGGAPGDLHCILISNPNEDTWKDPALEKLSLFCEESRSFNDWVPSITLPE",
    "output": "Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPKHGKRYRALLEKVDPNKVYTIDEAARLVKELATAKFDETVEVHAKLGIDPRRSDQNVRGTVSLPHGLGKQVRVLAIAKGEKIKEAEEAGADYVGGEEIIQKILDGWMDFDAVVATPDVMGAVGSKLGRILGPRGLLPNPKAGTVGFNIGEIIREIKAGRIEFRNDKTGAIHAPVGKASFPPEKLADNIRAFIRALEAHKPEGAKGTFLRSVYVTTTMGPSVRINPHS",
    "output": "Directly binds to 23S rRNA. Forms what is known as the L1 stalk, which protrudes beyond the 70S ribosome surface. The stalk is preferentially stabilized in 70S versus 50S crystals. Interacts with the E site tRNA, blocking the exit path. This blockage implies that this section of the ribosome must be able to move to release the deacetylated tRNA.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKILSLRLKNFRNYKEAEVSLSPDMNYIFGENAQGKTNLLEALYVLSLGRSFRTTHLTEAIFFGSSHFFLEMTFEKDGFCHTLSTYVDKQGKKILCDHSPIKTLSQLIGMVPIVLFSSKDRSLISGAPADRRLFLNLLLSQCDPQYKHTLSYYHRALLQRNTLLKTKQTSTLSVWDEQLATLGAYLTVSRYFCCEQLNQLVQELWSNSLSEQLRIKFKSSLIKQGNLSQEAIIEELRKQLTTALHRDLELGTTSVGPHREDFTLMINDLSVAQFSSEGQKHSLLAILRLAECLYIKNIYNACPLFCMDDIHAGLDNHRISQLLDLAPTLGQTLMTSTNIPHQSLSETSKIFSVNQAQISIHSHLIVN",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKKMKLSEITNMFAGMNVEALEGVTIEGDIEIDLGGLGGFDPMLAAALGQESAVLAQHFARIAGMFGYPVSVGAPAAAPAAVSPALAAPKLKDLIPAKFEFSNIEEWTTQVEEVPIGNTSADGGSRGKRILLGGEKALPFFPDAPMPNRNQVTIDVFDMRLGLAKAVKENYDDVMDNPGEWAKKNVEKFNADMITIHLISTDPLIKDTSPKDAAKTVEEVLQAVDVPIAIGGSGNPQKDPLVLAKAAEVAEGERCLLASASLNLDYAAIAEAALKYDHDVLSWTQLDMNAQKELNRKLMKQCNVPRDRIIMDPTTAALGYGLDYAYTNMERIRLAALMGDDELTFPMSSGTTNAWGARESWMVSSPLKEDSDWGPREYRGPIWEIITGLSLAIAGNDLFMMMHPTSVAVLKHMTQTLFGSIEAEPVDIANWIGAEV",
    "output": "Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKSLLFTLAVFMLLAQLVSGNWYVKKCLNDVGICKKKCKPGEMHIKNGWATCGKQRDCCVPADRRANYPAFCVQTKTTRTSTVTAKTTLMVTTASMSSMAPTPVSPTG",
    "output": "Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other surface components and allows sperm to penetrate the cumulus matrix and bind to the zona pellucida of the oocyte. In vitro has antimicrobial activity and may inhibit LPS-mediated inflammation (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSQISMFVRKLHKFSYNPNYKFKCGLEIHTQLKTKYKLFSLSPTSYNEPPNTKLSYFDVGLPGTQPLLNPEALLLALKASVALNCDIQSYSSFDRKHYFYADQPLGYQITQHYYPLAKNGYVQLNKFDDMPDKVISLEQVQLEQDTGKTVNYDDRINVDLNRANTPLIEVVTKPDFENIDQVQAFVRKYQLLVSHLDICTGDLETGAIRVDANISVNNNPRVEIKNLGSSGEIVDALKYEYNRQVTLLQNNGKIIQETRGWNGIATESLRKKENAVDYRYVPDSELPVIRLDKNIQAQLQNTLDELPDSVLDRLTKEPYNLQLAHARNLLFQPEILDYYENIFGRIRDANKWFFHELLAAFAKSDVEFQVDIVLPDMLVDIVSSVEKNEISLTGARIILKHIIRNKSTKTLPQLIKELDIGKPEASAELEEAINEICQQIINTNADVVEKIARGHTNALQVLIGQAMKATKGKVHAKEFRSKFMELLK",
    "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRNLGLLEITLLCSLFVYFRIDSVSSLNSDGLALLSLLKHFDKVPLEVASTWKENTSETTPCNNNWFGVICDLSGNVVETLNLSASGLSGQLGSEIGELKSLVTLDLSLNSFSGLLPSTLGNCTSLEYLDLSNNDFSGEVPDIFGSLQNLTFLYLDRNNLSGLIPASVGGLIELVDLRMSYNNLSGTIPELLGNCSKLEYLALNNNKLNGSLPASLYLLENLGELFVSNNSLGGRLHFGSSNCKKLVSLDLSFNDFQGGVPPEIGNCSSLHSLVMVKCNLTGTIPSSMGMLRKVSVIDLSDNRLSGNIPQELGNCSSLETLKLNDNQLQGEIPPALSKLKKLQSLELFFNKLSGEIPIGIWKIQSLTQMLVYNNTLTGELPVEVTQLKHLKKLTLFNNGFYGDIPMSLGLNRSLEEVDLLGNRFTGEIPPHLCHGQKLRLFILGSNQLHGKIPASIRQCKTLERVRLEDNKLSGVLPEFPESLSLSYVNLGSNSFEGSIPRSLGSCKNLLTIDLSQNKLTGLIPPELGNLQSLGLLNLSHNYLEGPLPSQLSGCARLLYFDVGSNSLNGSIPSSFRSWKSLSTLVLSDNNFLGAIPQFLAELDRLSDLRIARNAFGGKIPSSVGLLKSLRYGLDLSANVFTGEIPTTLGALINLERLNISNNKLTGPLSVLQSLKSLNQVDVSYNQFTGPIPVNLLSNSSKFSGNPDLCIQASYSVSAIIRKEFKSCKGQVKLSTWKIALIAAGSSLSVLALLFALFLVLCRCKRGTKTEDANILAEEGLSLLLNKVLAATDNLDDKYIIGRGAHGVVYRASLGSGEEYAVKKLIFAEHIRANQNMKREIETIGLVRHRNLIRLERFWMRKEDGLMLYQYMPNGSLHDVLHRGNQGEAVLDWSARFNIALGISHGLAYLHHDCHPPIIHRDIKPENILMDSDMEPHIGDFGLARILDDSTVSTATVTGTTGYIAPENAYKTVRSKESDVYSYGVVLLELVTGKRALDRSFPEDINIVSWVRSVLSSYEDEDDTAGPIVDPKLVDELLDTKLREQAIQVTDLALRCTDKRPENRPSMRDVVKDLTDLESFVRSTSGSVH",
    "output": "Acts as a receptor for PEP defense peptides. Unlike typical immune receptors, senses an endogenous elicitor that potentiates PAMP-inducible plant responses (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGILLGLFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVIFPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQITLHILPPTQVAMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFGAGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNGYLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPELAVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE",
    "output": "Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPHSHPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATVTALRRTVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFISNHAY",
    "output": "Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPLFFSDNLRAALECLLFVAGGPVSVDSLAACLGVKPGDVDELAAELQELYAREERGLQIRAVAGGYQMCTRPEFASYCEALLRPELPALSRAALETLAIIAYRQPVTRTEMEYIRGVKVDGVLNTLISRGLVQEVGRKEAPGRPILYGTTPKFLEFFGLKDLKELPPLEDVAASQENSREAGGRGSIPGHPGEE",
    "output": "Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEKQAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDSINDEAVIERIKGKVLDICARYPVYA",
    "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKSEYDVIVVGAGPGGSLAAKTAAEQGLDVLLIEKRQEIGDPVRCAEGVGKAGLQEFVEPDPKWISADIKCARIFSPDGTMVELSEKMAGNEVGFVLERKIFDRELAKMAAKAGAEVQVKTQATGLIIENGQVCGITGKRHGDEFTARAKVVVAADGVESKVGRWAGINTTLKMKDIETCAQFLMTDINIKPNSCDFYLGSKYAPGGYVWVFPKGDREANVGLGMLASHYKGKHPIEYLREFVADKFPEGKILETVVGAVPVSGMLPKLSTGGLVLVGDAGHVSDPITGGGIINAMSSGRIAGNIIANCIRAGDVSAKALSRYDAEVREALGKSLDKNYKIKEVVTKVSDNTMNVAAHSLQGVDFENVTVTKLVKEIVTRNPALLKELVGLI",
    "output": "Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA",
    "output": "Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEMSFRWYGEDDPVTLENIGQIPTMKGIVTAIYDVPVGEVWSRERIQQLKEKVEAAGLKISVIESVPVHEDIKLGRPTRDLLIDNYIQTVKNLAAEGIDTICYNFMPVFDWTRTDLAYQYPDGSTALIFDETVSKKMDPVNGELSLPGWDASYSKEEMKAIMDAYAEIDEEKLWENLTYFIKRIIPEAEAVGVKMAIHPDDPPYSIFGLPRIITGLEAIERFVKLYDSKSNGITLCVGSYASDPQNDVLEISRRAFELDRVNFVHARNIKLGDGKSFKESAHPSEYGSIDMYEVIKLCHEFGFEGAIRPDHGRMIWGETGRPGYGLYDRALGATYLSGLYEAVIKGSK",
    "output": "Catalyzes the dehydration of D-mannonate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLNKELLDALNEQMNHEFYAAHAYMAMAAFCDDNSYEGFANFYIQQAKEERFHGKKIYDYINDRGEHALFTAIPAPKTEFSSILETFEDGLAQEQDVTHRFYNLSDLANKDKDYATISFLNWFLDEQVEEEAMFETHIDYLNRIGDDSNTLYLYEKELAARSFDESE",
    "output": "Iron-storage protein."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEEIKETVEKKNKEKKYLNDYKIISEGNNIKVLQKKDFKPKFSLVSYKNYEQNFDFENAKIVSTNFAIDRHIKMKNPPDPFVFIKMPSSKLVQSQLKLYYENEGYKDIPVWITPCSAFMRYIKSYPIVGTVTETMEKKKGFTNRFLSTSETKASVSVGFFGCESSMEVTSGYEYEDTVTSEETRSWSQTLNEGSYIVYQNVLVYAYIIYGGSYKPYIDQMNKFNPGLNIKFFREDKCIFFVPINRDDAFTLRYQDNTWDPVEYDVLIDYLGQNQDKWFSGGLP",
    "output": "Knockout of the gene for this protein causes small aggregate formation. May regulate the secretion or processing of a secreted factor that regulates aggregate size."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSATANLKKDYQERIVPALMKQFGYTSVMQVPVLKKIVINQGLGMATGDKKIIDVAVSELTAITGQKAVPTVSKKDISNFKLRKKMPIGVMVTLRREQMYEFLERLVRIALPRIRDFKGIESKLDGRGNYTLGINEQIIFPEINIDAITKILGMNITFVTSAQSDEEGYALLKEFGLPFKNAKKQN",
    "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGPVTRELRTEKFMKIISLAPEVL",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSPRSNKPKIVNGPGGYILQDVPHLIDYLPDLPTYPNPLQDNPAYSVVKQYFVHADDSVPEKVVVHKDGPRGVHFRRAGPRQKVYFESDEVHACIVTCGGLCPGLNTVIREVVSSLSYMYGVKRILGIDGGYRGFYAKNTIPLNSKVVNDIHKRGGTIIGTSRGGHDTNKIVDSIQDRGINQVYIIGGDGTQRGASVIFEEIRRRRLKVAVVGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHVEAESNENGIGFVKLMGRYSGYIAMYATLASRDVDCCLIPESPFYLEGEGGLFEFIERRLKDHGHMVIVLAEGAGQDLMCKSMESTPMDASGNKLLKDVGLWLSQSIKDHFKKNKMVMNLKYIDPTYMIRAVPSNASDNVYCTLLAQSAVHGAMAGYTGYTSGLVNGRQTYIPFYRITETQNNVVITDRMWARLLSSTNQPSFLGPKDTSEEKKELPETPLLDDGAVDIPPVTKEVTK",
    "output": "Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKRRNFIQLSSLATIGMSLPSAGIVNACSSFPEQSLEFKNLTSELLKEWCDGMLKVQINNPSNLEEHGALRCPSCSHIHGRCMDAVYPFLYMADVSGDEKYIEAAKLVMIWAENNVSQENGAWTVIPNPKSWKGITIFGAIALAESLHYHSHILDDKTLKAWTNRLARAGQYIYDTFTIDFTNINYGGTAIYGLDIIGDVLGNGNFKEKSKKMAEEVQAFFTKNDYLLYGECKPEADKLSAKGLHGVDLGYNVEETLNSLVMYALKNDDQALLQIVTKSLNSHLEFMLPDGGWDNSWGNRMYKWTYWGSRTCDGSQPAFAMMAHINPAFGTAAVKNTELLKQCTANGLLHGGPHYISAGIPPCVHHTFTHAKPLAALLDHWKHLPEINKTTALPRVTANGIKHFKDLDVLLFSRGDWRGTVSAYDAEYHYKKDYRQATGGSLGILYHNKVGLLCAASMAVYNMVEPYNQQPQPGKDIALTPRIETFKEDQWYTNLYDLTANLEAIDTKEVINLASVVKLKNESRKMVSGTASEFHLTYSCAKEGLTIKVSTQQDILEPTAFVLPIASPEKEKVEFVNEHEIKISKPGGVVTIKANVPLKLKEYSGTRTFNMVPGLEALPIELFFETHIKELVLIVSVV",
    "output": "Broad-specificity lyase involved in ulvan degradation . Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl)  (Probable). Ulvan lyase catalyzes the endolytic cleavage of the glycosidic bond between Rha3S and the uronic acids GlcA or IduA, producing oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) at the non-reducing end. This results eventually in the degradation of the ulvan polysaccharide into deltaUA-Rha3S disaccharides and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides. It is also able to degrade the glycosaminoglycans heparan sulfate and chondroitin sulfate. Not active against pectin, xanthan or alginate ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDCNCFDPQWPADELLMKYQYISDFFIAVAYFSIPIELVYFVQKSAVFPYRWVLVQFGAFIVLCGATHLINLWTSTAHTRTLAIVMTTAKVLTAVVSCATALMLVHIIPDLLSVKTRELFLKNKAAELDREMGLIRTQEETGRYVRMLTHEIRSTLDRHTILKTTLVELGRTLALEECALWMPTPPGLELQLSYTLRHQNPIGFTVPIQLPVINQVFGTNRAVKISPNSPVARLRPAGKYMPGEVVAVRVPLLHLSNFQINDWPELSTKRYALMVLMLPSGSARQWHVHELELVEVVADQVAVALSHAAILEESMRARDLLMEQNVALDLARREAEMAVRARNDFLAVMNHEMRTPMHAIIALSSLLQETELTPEQRLMVETILKSSNLLATLINDVLDLSRLEDGSLQLDVGTFNLHVLFRKVLNLIKPIASVKNCLSRLTCLQICPEFAIGDEKRLMQILLNVVGNAVKFSKEGSVSISAVAAKSESLSDPRAPEFFPVQSENHFYLRVQVKDTGSGINPQDIPKLFCKFAQNQALATKSSGGTGLGLAISKRFVNLMEGHIWIESEGLGKGSTAIFIVKLGIPGRSNEPKLPFMPRLPANHMQMTFQGLKVLIMDDNGFSRMVTKGLLVHLGCDVTTVSSGDECLRVLTQEHKVVFMDVSIPGIDCYEVAVQIHEKFGKHHNRPLIVALTGNTDRVTKENCMRVGMDGVILKPVSVDKMRSVLSELLEHGVILQS",
    "output": "May act early in the ethylene signal transduction pathway, possibly as an ethylene receptor, or as a regulator of the pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTQNIGKITQVISAVVDVKFTNNSKLPEILNALECYNAKQRIVLEVAQHIGDDTVRCISMGSTEGLIRGLEVIDTGNPIHIPVGIATLGRIMNVVGEPIDGKGEIKSSTISSIYKPAPDFINQSTERDILVTGIKVVDLLAPYTKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYTVFAGVGERTREGNDLYHEMIASGVINLEAPEKSKVALVYGQMNEPPGARARVALSGLTIAESFRDMNAGQDVLFFVDNIFRFTQAGAEVSALLGRIPSAVGYQPTLATDMGELQERITSTKHGSITSVQAIYVPADDLTDPAPSTSFAHLDATTVLSRQIAELGIYPAVDPLDSNSQVLDPMIVGEEHYSVARQVQQVLQTYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFHVAEVFTGVEGKFVNLDDTIAGFKGLVEGKYDDLPEAAFYMVGTIDEAVEKAKILKI",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDYAVRKISHMRIFSDSEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDKASQLYNSFNDHLEELVPVKRGVFGADMQVSLINDGPVTIILDTKNR",
    "output": "An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRSIASKKLVIATHNTGKLHEITTLVAPFGLEIQSAKELDLPEPKETGVTFEENAYIKAFAAAKNTGLPALSDDSGLEVDALGGAPGVYTADWALQSDGTRNFSKAMQKIEDELQKIGAHEKSQRKARFISVICIAWSDAYADYFRGSVEGTFIWPPRGDKGFGFDPIFLPDGYENTFGEMSTEQKHGWKLNDKTPLSHRARAFKLLAENLLTLS",
    "output": "Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MHRYRTHTCGAIRPSDVGQTVRLSGWCHRIRDHGGVLFIDLRDHYGLTQCVIDSDSKAFKAAETARSEWVIRIDGRVRTRPAGTENAELPTGSVEVYIDDLEVLGPAGELPLPVFGDQEYPEETRLKYRFLDLRREKLHANIMKRGAIVDSLRRRMREGGFFEFQTPILTASSPEGARDYLVPSRVHPGKFYALPQAPQQFKQLTMIAGFDRYFQIAPCFRDEDARADRSPGEFYQLDIEMSFVTQEDVFQAVEPVLRGVFEEFAGGKRVTKEFPRITYADAMLKYGVDKPDLRNPLIIADVTDEFADDAVEFKAFKGVIKSGGVVRAIPATGAAGQPRSFFDKLNDWARSEGAPGLGYIVFEEEGGALTGKGPIAKFIPAAIQARIAEKAGAKAGDAVFFAAGTEAKAAGLAGKARIRIGDELKLSDTDQFAFCWVVDFPMYEWNEEDKKIDFSHNPFSMPNFDRDEFLALGEADSEKILGIKAFQYDIVCNGIELSSGAIRNHRPDVMEKAFAIAGYGRDVLEEKFGGMLNALRLGAPPHGGIAPGVDRIVMLLCEEPNIREVVLFPMNQRAEDLMMGAPAEATPKQLRELHIRLNLPEKKA",
    "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRRRRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQEASFLQVHDFFQQDLKEGFHVSMLNRRTTPV",
    "output": "Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit . Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MWSYVWLPLVALSLFKDSIIMAKAATILLPSQTGFDISRSPVCSAPDPNLNYRPVIGILSHPGDGASGRLSNATDASSIAASYVKLAESGGARVIPLIFNEPEEILFQKLELVNGVILTGGWAKEGLYFEIVKKIFNKVLERNDAGEHFPIYAICLGFELLTMIISQNRDIFEKMDARNSASSLQFVENVNIQGTIFQRFPPELLKKLGTDCLVMQNHRFGISPQSFEGNIALSNFFKIVTTCVDDNGKVYVSTVQSTKYPVTGFQWHPEKNAFEWGSSKIPHSEDAIQVTQHAANHLVSEARKSLNRPESKKVLSNLIYNYKPTYCGYAGIGYDEVYIFTQQRSLL",
    "output": "Cleaves the polyglutamate sidechains of folate polyglutamates in the vacuole. Is important for polyglutamyl tail length determination before vacuolar exit. Plays a role on folate stability and intracellular folate content. Has endopeptidase activity against 4-amino-10-methylpteroyl penta-, tetra-, tri- and di-gamma-L-glutamate substrates and is responsible for the production of folic acid, also called pteroylglutamic acid (PteGlu) from teroylpolyglutamates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAETVEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQWQSIVEANNQRPPMWLRINRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVHALPGFEDGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKTGGTLVYATCSVLPEENSLQIKAFLQRTADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK",
    "output": "Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNAGQLPPELQRVHMVGIGGSGMSGIARILLDRGGLVSGSDAKESRVVHALRARGALIRIGHDASLLDLLPGGATAVITIRTAIPKTNPELVEARRRGIPVLLRSAVLARLMDGCTTLMVAGTHGKTTTTSMLVVALQHCGCDPSFVVGGELAVVGTNAHHGLGACFVAEADESDGSLLEYTPNVAVVTNIDSDHLDFYGSVDAYIRVFDSFVERFALGGALVVCNDDPGAAALARRTAELGIRVLRYGSDDRIGETLAARLLSWEQQGTGAVAHIQLAGQPNSRVMRLPVPGRHMALNALGALLAAIEIGASTDEVLDGLAGFRGVRRRFELVGTSGVGQASNSLVRVFDDYAHHPTEISATLAAFRIMLEQSGGGRCIVVFQPHLYSRTKALSREFGRALSAADEVFIVGVNGAREQPLAGVSGASVAKHVSVPVRYIPDYSAVVIEVAAAAGPGDVIVTMGIGDVGLLGPEIVAALRVRANCNTPGCSGVLQ",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIKLVLLRHGESQWNRENRFTGWHDIDLTENGRNEAFQAGRLMKEAGLVFDMAYTSVLKRAIRTLWNAMDSMDLMWISVFKSWRLNERHYGALQGLNKSETSRKYGEEQVLVWRRSYDTPPPLLEKSDARYPGTDPRYGDLSEAEIPLSECLKDTVERFLPIWHETIAPQLRKGKRVIIVAHGNSLRALVKYLDNISEEDIVGLNIPTGIPLVYELDDDLKPLKNYYLGDQEALKKAVDAVAGQSKA",
    "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTAPRLTLPSPAKLNLMLHILGRREDGYHELQTLFQFLDYGDEITFAVRDDGVIRLHTEFDGVPHDSNLIVRAAKKLQEQSACSLGIDIWIDKILPMGGGIGGGSSNAATTLLGLNHLWRLGWDEDRLAALGLTLGADVPVFVRGHAAFAEGVGEKLTPVEPAEPWYVVLVPQVSVSTAEIFSDPLLTRNTPPIKVRPVPEGNSRNDCLPVVSRRYPEVRNALNLLGNFTEAKLTGTGSCVFGGFPSKAEADKVSALLTETLTGFVAKGSNVSMLHRKLQSLL",
    "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK",
    "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPIIKSAIERAKTNVKANERNSAQLSTMRTAVKRFEQAKTAGADNAEELYRKASAAVDKAASKGLIKRNKASRDKSRMAARLAK",
    "output": "Binds directly to 16S ribosomal RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA",
    "output": "Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis . Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion. Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm . Also plays an important role in the exocytosis of hormones such as insulin or glucagon-like peptide 1 (GLP-1) (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVKVGVIGLQGDVSEHIEAAQRALENLGVSGEVIWLKKPEQLEGISAIIIPGGESTTISRLMQKNGLLEPVRKLGEEGLPIMGTCAGLIMLSKEVIGATPEQRFLELLDVKVNRNAYGRQVDSFEAPVKLAFSDEPFPGVFIRAPRIVELLSDKVKPIAWLGDRVVGVEQDNLIGLEFHPELTEDTRVHEYFLRKAL",
    "output": "Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSKQFKILVNEDYQVNVPSLPIRDVLQEIKYCYRNGFEGYVFVPEYCRDLVDCDRKDHYVIGVLGNGVSDLKPVLLTEPSVMLQGFIVRANCNGVLEDFDLKIARTGRGAIYVDQYMCGADGKPVIEGDFKDYFGDEDIIEFEGEEYHCAWTTVRDEKPLNQQTLFTIQEIQYNLDIPHKLPNCATRHVAPPVKKNSKIVLSEDYKKLYDIFGSPFMGNGDCLSKCFDTLHFIAATLRCPCGSESSGVGDWTGFKTACCGLSGKVKGVTLGDIKPGDAVVTSMSAGKGVKFFANCVLQYAGDVEGVSIWKVIKTFTVDETVCTPGFEGELNDFIKPESKSLVACSVKRAFITGDIDDAVHDCIITGKLDLSTNLFGNVGLLFKKTPWFVQKCGALFVDAWKVVEELCGSLTLTYKQIYEVVASLCTSAFTIVNYKPTFVVPDNRVKDLVDKCVKVLVKAFDVFTQIITIAGIEAKCFVLGAKYLLFNNALVKLVSVKILGKKQKGLECAFFATSLVGATVNVTPKRTETATISLNKVDDVVAPGEGYIVIVGDMAFYKSGEYYFMMSSPNFVLTNNVFKAVKVPSYDIVYDVDNDTKSKMIAKLGSSFEYDGDIDAAIVKVNELLIEFRQQSLCFRAFKDDKSIFVEAYFKKYKMPACLAKHIGLWNIIKKDSCKRGFLNLFNHLNELEDIKETNIQAIKNILCPDPLLDLDYGAIWYNCMPGCSDPSVLGSVQLLIGNGVKVVCDGCKGFANQLSKGYNKLCNAARNDIEIGGIPFSTFKTPTNTFIEMTDAIYSVIEQGKALSFRDADVPVVDNGTISTADWSEPILLEPAEYVKPKNNGNVIVIAGYTFYKDEDEHFYPYGFGKIVQRMYNKMGGGDKTVSFSEEVDVQEIAPVTRVKLEFEFDNEIVTGVLERAIGTRYKFTGTTWEEFEESISEELDAIFDTLANQGVELEGYFIYDTCGGFDIKNPDGIMISQYDINITADEKSEVSASSEEEEVESVEEDPENEIVEASEGAEGTSSQEEVETVEVADITSTEEDVDIVEVSAKDDPWAAAVDVQEAEQFNPSLPPFKTTNLNGKIILKQGDNNCWINACCYQLQAFDFFNNEAWEKFKKGDVMDFVNLCYAATTLARGHSGDAEYLLELMLNDYSTAKIVLAAKCGCGEKEIVLERAVFKLTPLKESFNYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHAVYTGTTQNGHYMVDDIEHGYCVDGMGIKPLKKRCYTSTLFINANVMTRAEKPKQEFKVEKVEQQPIVEENKSSIEKEEIQSPKNDDLILPFYKAGKLSFYQGALDVLINFLEPDVIVNAANGDLKHMGGVARAIDVFTGGKLTERSKDYLKKNKSIAPGNAVFFENVIEHLSVLNAVGPRNGDSRVEAKLCNVYKAIAKCEGKILTPLISVGIFNVRLETSLQCLLKTVNDRGLNVFVYTDQERQTIENFFSCSIPVNVTEDNVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQKVIKAIDIDWQAHYGFRDAAAFSASSHDAYKFEVVTHSNFIVHKQTDNNCWINAICLALQRLKPQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDAELMLHKLGDLMDNDCEIIVTHTTACDKCAKVEKFVGPVVAAPLAIHGTDETCVHGVSVNVKVTQIKGTVAITSLIGPIIGEVLEATGYICYSGSNRNGHYTYYDNRNGLVVDAEKAYHFNRDLLQVTTAIASNFVVKKPQAEERPKNCAFNKVAASPKIVQEQKLLAIESGANYALTEFGRYADMFFMAGDKILRLLLEVFKYLLVLFMCLRSTKMPKVKVKPPLAFKDFGAKVRTLNYMRQLNKPSVWRYAKLVLLLIAIYNFFYLFVSIPVVHKLTCNGAVQAYKNSSFIKSAVCGNSILCKACLASYDELADFQHLQVTWDFKSDPLWNRLVQLSYFAFLAVFGNNYVRCFLMYFVSQYLNLWLSYFGYVEYSWFLHVVNFESISAEFVIVVIVVKAVLALKHIVFACSNPSCKTCSRTARQTRIPIQVVVNGSMKTVYVHANGTGKFCKKHNFYCKNCDSYGFENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVECSDGFYRFYVGDEFTSYDYDVKHKKYSSQEVLKSMLLLDDFIVYSPSGSALANVRNACVYFSQLIGKPIKIVNSDLLEDLSVDFKGALFNAKKNVIKNSFNVDVSECKNLDECYRACNLNVSFSTFEMAVNNAHRFGILITDRSFNNFWPSKVKPGSSGVSAMDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSSTAQKVLVKTFVEEGVNFSLTFNAVGSDDDLPYERFTESVSPKSGSGFFDVITQLKQIVILVFVFIFICGLCSVYSVATQSYIESAEGYDYMVIKNGIVQPFDDTISCVHNTYKGFGDWFKAKYGFIPTFGKSCPIVVGTVFDLENMRPIPDVPAYVSIVGRSLVFAINAAFGVTNMCYDHTGNAVSKDSYFDTCVFNTACTTLTGLGGTIVYCAKQGLVEGAKLYSDLMPDYYYEHASGNMVKLPAIIRGLGLRFVKTQATTYCRVGECIDSKAGFCFGGDNWFVYDNEFGNGYICGNSVLGFFKNVFKLFNSNMSVVATSGAMLVNIIIACLAIAMCYGVLKFKKIFGDCTFLIVMIIVTLVVNNVSYFVTQNTFFMIIYAIVYYFITRKLAYPGILDAGFIIAYINMAPWYVITAYILVFLYDSLPSLFKLKVSTNLFEGDKFVGNFESAAMGTFVIDMRSYETIVNSTSIARIKSYANSFNKYKYYTGSMGEADYRMACYAHLGKALMDYSVNRTDMLYTPPTVSVNSTLQSGLRKMAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVIASDTTRVINYENEMSSVRLHNFSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIKAGESFNILACYEGCPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLELGNGSHVGSNFEGEMYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSLESYNTWAKTNSFTELSSTDAFSMLAAKTGQSVEKLLDSIVRLNKGFGGRTILSYGSLCDEFTPTEVIRQMYGVNLQAGKVKSFFYPIMTAMTILFAFWLEFFMYTPFTWINPTFVSIVLAVTTLISTVFVSGIKHKMLFFMSFVLPSVILVTAHNLFWDFSYYESLQSIVENTNTMFLPVDMQGVMLTVFCFIVFVTYSVRFFTCKQSWFSLAVTTILVIFNMVKIFGTSDEPWTENQIAFCFVNMLTMIVSLTTKDWMVVIASYRIAYYIVVCVMPSAFVSDFGFMKCISIVYMACGYLFCCYYGILYWVNRFTCMTCGVYQFTVSAAELKYMTANNLSAPKNAYDAMILSAKLIGVGGKRNIKISTVQSKLTEMKCTNVVLLGLLSKMHVESNSKEWNYCVGLHNEINLCDDPEIVLEKLLALIAFFLSKHNTCDLSELIESYFENTTILQSVASAYAALPSWIALEKARADLEEAKKNDVSPQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVVITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAANELNLTWPLSITCERTTKLQNNEIMPGKLKERAVRASATLDGEAFGSGKALMASESGKSFMYAFIASDNNLKYVKWESNNDIIPIELEAPLRFYVDGANGPEVKYLYFVKNLNTLRRGAVLGYIGATVRLQAGKPTEHPSNSSLLTLCAFSPDPAKAYVDAVKRGMQPVNNCVKMLSNGAGNGMAVTNGVEANTQQDSYGGASVCIYCRCHVEHPAIDGLCRYKGKFVQIPTGTQDPIRFCIENEVCVVCGCWLNNGCMCDRTSMQSFTVDQSYLNECGVLVQLD",
    "output": "The papain-like proteinase 1 (PLP1) and papain-like proteinase 2 (PLP2) are responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PLP2 possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. PLP2 also antagonizes innate immune induction of type I interferon by blocking the nuclear translocation of host IRF-3 (By similarity).; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRKSYRIKKEAEFQQVFETRNSVANRQFVVYSMEKPQQPHFRVGISVGKKIGNAVHRNWVKRRIRQSLLELKPHLKQDVDFLVIARPRADGISMTDAKRSLVHVLKLAKLLDSDYSEE",
    "output": "RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSNNALQTIINARLPGEEGLWQIHLQDGKISAIDAQSGVMPITENSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVKQRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGILSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHHEGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQVPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR",
    "output": "Catalyzes the hydrolytic deamination of cytosine to uracil. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis. Is also able to catalyze deamination of isoguanine, a mutagenic oxidation product of adenine in DNA, and of isocytosine. To a lesser extent, also catalyzes the conversion of 5-fluorocytosine (5FC) to 5-fluorouracil (5FU); this activity allows the formation of a cytotoxic chemotherapeutic agent from a non-cytotoxic precursor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPVFTASFQCVTLFGQPASAADAQPLLQGQRPFLHLHARRRRPCGPMLISKSPPYPASEETREWEADGQHEHTDELRETTTTMIDGIRTALRSIGEGEISISAYDTSLVALLKRLDGGDGPQFPSTIDWIVQNQLPDGSWGDASFFMMGDRIMSTLACVVALKSWNIHTDKCERGLLFIQENMWRLAHEEEDWMLVGFEIALPSLLDMAKDLDLDIPYDEPALKAIYAERERKLAKIPRDVLHSMPTTLLHSLEGMVDLDWEKLLKLRCLDGSFHCSPASTATAFQQTGDQKCFEYLDGIVKKFNGGVPCIYPLDVYERLWAVDRLTRLGISRHFTSEIEDCLDYIFRNWTPDGLAHTKNCPVKDIDDTAMGFRLLRLYGYQVDPCVLKKFEKDGKFFCLHGESNPSSVTPMYNTYRASQLKFPGDDGVLGRAEVFCRSFLQDRRGSNRMKDKWAIAKDIPGEVEYAMDYPWKASLPRIETRLYLDQYGGSGDVWIGKVLHRMTLFCNDLYLKAAKADFSNFQKECRVELNGLRRWYLRSNLEKFGGTDPQTTLMTSYFLASANIFEANRAAERLGWARVALLADAVSSHFRRIGGPKNSTSNLEELISLVPFDDAYSGSLREAWKQWLMAWTAKESSQESIEGDTAILLVRAIEIFGGRHVLTGQRPDLWEYSQLEQLTSSICCKLSRRVLAQENGESTEKVEEIDQQVDLEMQELTRRVLQGCSAINRLTRETFLHVVKSFCYVAYCSPETIDSHIDKVIFQDVI",
    "output": "Catalyzes the conversion of geranylgeranyl diphosphate to the phytoalexin precursor syn-copalyl diphosphate . Required for the biosynthesis of momilactones that exude from roots and act as allelochemicals against lowland weeds in paddy soil ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDKINQTFVREFILLGLSGYPKLEIIFFALILVMYVVILIGNGVLIIASILDSRLHMPMYFFLGNLSFLDICYTTSSIPSTLVSLISKKRNISFSGCAVQMFFGFAMGSTECFLLGMMAFDRYVAICNPLRYPIIMNKVVYVLLTSVSWLSGGINSTVQTSLAMRWPFCGNNIINHFLCEILAVLKLACSDISVNIVTLAVSNIAFLVLPLLVIFFSYMFILYTILRTNSATGRHKAFSTCSAHLTVVIIFYGTIFFMYAKPKSQDLLGKDNLQATEGLVSMFYGVVTPMLNPIIYSLRNKDVKAAIKYLLSRKAINQ",
    "output": "Odorant receptor."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLGLLKKVVGDPSQRQLKKNQKIADQVEALSDEMKSLSDDGLRQKTEEFKKRYKNGESLDDLLPEAYAVVREAATRVLNMTPYPVQILGAIALHQGNIAEMKTGEGKTLVGTMPVYLNALAGKGVHVVTVNDYLARRDSEQMGAMFEFLGLTVGLNVPGLSKEEKKEAYQADITYGTNNEFGFDYLRDNMVLYKEQMVQRSLNFALVDEVDSILIDEARTPLIISGSVERSTKLYSQANSFVRVLKNEEDYTLDEKTKSVQLTEEGVNKAERAFNIDNLFDQRHVQLLHHINQAMKAHVVMHRDADYVVENGEIVIVDQFTGRLMKGRRYSDGLHQAIEAKEGLQIQRESMTLASITFQNYFRMYQKLAGMTGTAKTEEEEFRNIYGMDVMVIPTNKPVIRDDRPDLIFKTMDAKFKAVVNEIEELYKKGQPVLVGTVSVETSELVSTLLKKRRIPHHVLNAKNHEKEAEIIENAGHRGAVTIATNMAGRGTDIKLGEGVRELGGLHVLGTERHESRRIDNQLRGRSGRQGDPGSSQFYLSMEDELMRRFGSDNMRAMMDKLGMEEDQPIESKLVSRAVETAQKRVEGNNFDARKQILQYDDVMREQREIIYKQRMEVLESDNLREIVEKMILSVIERNVQLHTPESEVPEDWDYGAIVNFMKANLLNEDDLTEKDIWGKDPEEIVEIIYDKVIERYNKKEEEFTPEHMREFEKVIMLRTVDRKWMNHIDQMDQLRQGIHLRAYGQNDPLREYRFEGFEMFEAMVASIEEEVAMYVMKAQVQQNLQREKVAEGQAVQPKPTDGDSKAKRQPVRKKETVGRNEPCPCGSGKKYKNCCGQ",
    "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGTLHGEKTMFASPNTFYIDESKLCFNKTHFNREDFNVERFMNLARQKSDLKTIQQDLRLYLKSVQNSMIELINDDYADFVHLSSNLVSLQDSLNKIEQDINRIWDEFKESTRESVGMAERIEQKCDELCSNREKQIEIRDRIYFLVAIEKLSEMLLHPPRKCSALWLQKAASFASELKGSTFPHSEEENAAEKIILSQLEAVLCAEGVRSAAGDCQNLPLIYSILSLTESTHSLTALLVSDLLYAEFVNEKHDESNQLKLLKQVFESVKKMRETWAEKMGTEHFRGNIRRFLDETLLTFILTFIDKCMGAVAVPSDTRLFHECFLLTQEFIDNWPSSHTCRAMLKSIRDKFNLLVYFKLETHRFGKQCDQLMSPEMFAEPETSENRENTPQLHCGVSRAIITAIEHVWSDDVYLPPIVDKLWDFTLKLLLKHFSWSQTMKNYFMEEKRDWTSMVTLRSDTGNLHQLVFDFALESIWGKFHDITVDTAPFGQCLTKHGRSIDSLCVQIDDSIIEMFSEVLHQEIAQVSDVPKQYRWTKKSPPTTHSKYVVTAIEMVENLKEKLCCEEHPHTDEIVRKVNLSAFNYFVGKGNEVLDSVEATGSSLSRFKRKTTTDSGSTVTDDDKIKQQIYHDAKYFLSYAENLVFSQADLTGLQEVVNRFDKDARSAIVQEKNQNEEAGNA",
    "output": "Required for normal Golgi morphology and function."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVALNIWLLVGTALGL",
    "output": "H(+)-stimulated, divalent metal cation uptake system."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTGILAVQGAFAEHAAMLDHLGAPWKLLRAAEDFDDSIDRVILPGGESTTQGKLLRSTGLFEPIAEHIAAGKPVFGTCAGMILLARKLDNDDNVYFGALDAVVRRNAYGRQLGSFAATADFGSSSGDSAVVVAPGEHVPQDAPADIVLKDFPLVFIRGPFVAEVGPAATVETSVDGNVVGLRQGKILATAFHPELTDDTRIHELFLSL",
    "output": "Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQKDYPYALIQFYATAPYTCSYLSDRVARSQVATPGHLIDTPVYSELVRNGFRRSGMFTYRPYCDHCRACVPVRIPVKRFEPDRSQRRAWKMHHELRANEQPLAYSEEHYALYQRYQGSRHAGGGMDQDNREQYAHFLLQSHVDTRLVEFREGDVLRMVSVIDRLSDGLSSVYTFYDPDQTHASYGTYGILWQIEVCRRLKLPYLYLGYWIKESRKMTYKVRFHPLEGRLRGEWRDIDPLRDRASE",
    "output": "Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFFVDVM",
    "output": "Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGQKIHPVGFRLGITQEHQSRWFAEPSRYPELLQEDHKLRQYIEQKLGRLAQNNAGISEVRIERKADQIDLEVRTARPGVVVGRGGQGIEALRTGLQTLLGGNRQIRINVVEVQRVDADAYLIAEFIAQQLERRVSFRRVVRQAIQRAQKAGIQGIKVQVSGRLNGAEIARTEWTREGRVPLHTLRADIDYSYCTAKTVYGILGIKVWVFKGEIIPGQEVATPPPSPRDRDRDRGDRDREPRRRQQQRRRQQFEDRSNEG",
    "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNVSAYLPTCLPTYLPTCLPTYLPTYLPTYLPICLSEENNGIGIIGIGFRLPGGGSGKSLGNPSELWKELVNGYDGIIETNERWSDNFNKLGEINNRYGGLLPMDEVKSFDPLFFGISPPEATAIDPQQRLLLKCTWEAIEDAMIDPINLRGSNTSVFIGNTTHEYRDLNRTIDSIQTNIFSSSSHSSSNRVSNIFDFHGPSITIDTACSSSSNAVVLGCKSIIEGNSKMSIVGGTSLIFDANTPKSFSYMNMLSKDGRCKSFDANADGYVKSECIGVLLLKDLNQAIIDGDRVYCVIKGTSSNVDGNGYSDKSNFYSPSAQSQAENIKMALSSGNINAKDVDYVEAHGTGTPVGDPIEVEGISSIFKDNHSKENPLLIGSFKSMIGHCEASSGIASLVKCCLMFKNRYFIPNLHFKTPNPLIKFNEWNLKVVVEPTPFPKKEITMAVNNFGVTGSNVCIILKDFNYNHNSSSDNNNTINLKQQQHQNNIEYLIPFSANSTKSLEQYQSLISNFNQETMEFNDFVKEQIMSKSNSLYQRSVILGSNWNDFKDNLISTNNNIKTIKTTSSNISIKSKNPIIIMVFCGQGSQYNTMALELYKNEPIFRKTMDMLDNKLSKYYGFSILEKLRSIPVDDMKSIHNPALAQPAICMVQISLFELYKHWGIKPTFIVGHSLGEVTAAYCSGMIDLETECYLIYHRSIAQSTTTGCGRMLSINISPEKFIEQFSSRYPDVEISCYNSPTSIVIGGKEDQLNKISEELKSKGEFTSMLGSLSSFHTSSQKAIKEYILSLDYKSKESEIPIFSTVTTNLFDYKTTPYSPKYTYENILKSVNFTQTIENLYKHIENNQLGTDIVFIELAPHPTLQFYLKQMIPKDSSYFGKGDSISIYSPLHKKKNDVKEIRQTISQLYCQNGYNINFKCQFENINRSIVPTHKLPLYQWDEKQFWKINSLYENYYLTGPPIDILGNSITDSPFVKSYQTFINIKRKPFQYLKGHVVKGKFYFPGCGYIDNLLKIYPSQDITISTLEFSTPFIFTDDSVNHCLQTNIYPTGKTEYKVLFHFKDQKKNEWIQSSFGNFQLFKHNGEKSLKIFNQKYNIKDLIEKRCNLTKLTKEDLYDHIKLKTGLTYSGMFQAVSMCYLGDNCSLSVVSLELPKHLPDQKSFFNSSILDCCLHGMIGLVDEHCQLVFDRIEGFNLYSSNIPSARDQHTNVYVYSSLNAKMGDSYFASIVVMLEDGTVLIEIDNAACTSLTPIQDSLKIEAPTNELYSTYLQSKDSLILPPQTFESLYQQEKGQNDILVGTIIKQSLVPFVNEKMVFRILDFSSGFADYNGTTFHSSNNVLEKFNQLLKEFPLCEIDIEYTFGSVPQSLTSSIKDKLSHINERVSILYRDYSINDPLLLEDNQLKPSQYDIVLINDLEKETNDIKATLYMIYNLMVPNGQLILINNDGNNLIEIKELLDQCNFKDTIISNDKKSIIQTRKPQLLSELSPNPNIDSYDQIIIYSNDDSEICNKFLKSLESTDDKILSIISTISKFNEFVEKQSITDKSVIYFIKTMEQLTLDNFKSITFEYIEINRKLLKLNSMCKHVLITSDSRKDNYLASSVIGAARYFDEFQQLQLFTLDFDKESIIEYTHNNNEKNLVSLIELLTDKKISIQKEYLIRNGKVYFERIKKEQNLRKKFKSESYQDLVENDLVAVLSPNLEYELKPMTKDLEPFEVQVEIKSFALNYKDYLTYIGSVPPEMVNHKTGDINDPEFGSDFSGVITRVSKNNCSEFKVGDQVYGTAYNTASSKSIIDSGSIYFKPNNLSHEQASTIPVVYSTSLHSIYNIGNLKNYESILIHSASGGVGLSSLNILKWKGHCSYIFLTVGSPEKEKYLRDTYGSLITGIYSTRDKSYVQKIKDKLKELGSDKTGVDLILNTLSSDYMDSNFNCLSKSGRIVDLSITHLNSNEYIDNKKFKFNYGYHNVELLFIAAPILKKLLKSISKAIENNELINNLPITQYSNVNIKNAFEYINQRKHIGKIVVNHDTDLVGNLIKEKINSTSNLDFTLLKSNYQININNLGKNIIVTGQSGIVFEIIKWIVKFAPLVENIIILSKSSMKWQLELLVNRNKHIKFHFKSVDVGDINSMGKAIDEVSNDIDNIDSIFHYAFHQITKNVEAINMDTLDISFGAKTIGAIILHDQSIKRGWKLKNFIIASSVTSSLGSESQCSYVCANNVLESFSQYRKSLGLPSICTSYGLIKSTGFVSRNENVSVMFENLGFNPLSINTILGSLDLQIQNQELSTNLIVSSFNFSNITKYNPQKNNFSKIDYQVSLEEKNKVNQLGHDGNQDNKNSVNQMFLEKVSEVLSIEISKINIDIKLSAYGADSLSIVQLKNWVDKELSGNIITIQQLQTNTISSSIKIITNSLDKKKEGKNKSSTVVNNTNEITTTTKTFEYWKNEAKLDETIIASSIKSDLIIDNKMDKVILLSGSTGFLGGYLLLNLVKMKNCSKIYCLTRSGHLSDQIDLMNKIIDNLKHHKLFEMFEQSELEKIFPVRGDLRKSKLGLSDKMYLEISNQVNLILSCGADINLNANYDEIKPTNVDSTKEFIKLSVSKGTNKPMIPIVNLSSFSIFFGQKLNDEIEFDEYQVGIPSLSNLNNLPGGYIQSKLICEHLLLEASSRGIPAMTIRLPSIFSNPHTGIGHSGDLLQLIIKSISVTKYFPIEPTSLFISPVTWVAQNIINLIFNEGCWSKTKINTLNIISLNGELQTTNEIFLMIKKNFNYKETTLINWKKMISESNDKTCIRLRTFHPLDFTPTKYHMSKEFKISKNTKSLLISFGSYDGWNITEQMVLNLLKQ",
    "output": "Probable polyketide synthase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEVKGKETASVLCLSKYVDLSSEESHRYYLARRNGLQMLRDRGYEVSDEDINLSLHDFRTVYGERPDVDRLRISALHRSDSTKKVKIVFFGTSMVKVNAIRSVVADILSQETITGLILVLQNHVTNQALKAIELFSFKVEIFQITDLLVNITKHSLKPQHQVLNDEEKTTLLKKFSIEEKQLPRISKKDAIVRYYGLEKGQVVKVNYRGELTESHVAFRCVW",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase V involved in RNA-directed DNA methylation-dependent (RdDM) silencing of endogenous repeated sequences, including transposable elements. Required for establishment of DNA methylation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKSAEWFEASTEEERVEIQRKVARKVRLEPLDDVDAVAGVDVSYRGEEYRAAAVVLDPETYEVLDRRVVHGTTDVPYEPGFLAFREGPPALEALEGLDFDLLFVHGHGVAHPRRAGLASHLGVALDVPTIGVARRPLVGRSKEEPSRIGDTTPLVHRGEVVGYLVRTDAEARPVVVSPGHRCNLEDAVRWTLRLVRVGKWPEPLRLADLLSRRGASRVEGESRGAGVRR",
    "output": "DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNSFGKRLIMTTFGESHGKAIGCVLDGVPAGLDIDETFIQNELDRRRPGKSKFATARKELDEVQILSGVFEGRSTGTPIAMVIFNKDQKSRDYSNIKDIFRPGHADFTYWHKYGIRDYRGGGRSSARETAARVAAGAVAKLLLKEFGIEVEAGVCEVAGIEAKEFDFDYAKTSEIFALDPYVETLQKEAILKAKEAHDSVGGAVLVRATNLPVGLGEPIYYKLDAVLAEALMSINAAKAVDIGLGREASRLYGSQNNDQITKEGFISNNAGGILGGISNGEDVIAKVWFKPTPSIFQKQRSIDVNGNEVEVELKGRHDPFVAARGSVVAEAMMALVIADMLLLNATSQLSHLKKVYL",
    "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAPFLRISFNSYELGSLQVEDEASQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKTTFDAHIYEGRVIQIVLMRAAEDPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMCVQYFLEDGDCKQSMRSEEEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKEFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTATNSRDTIFQKERFNIDMPHRFKVYNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRSSRKLDTTESVGIYQGFEKKPEVSGSDILDNNGTYGKIWEGSTRCTLENFTFQKVLGKGSFGKVLLAELKGKDKYFAIKCLKKDVVLIDDDVECTMVEKRVLALAWESPFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHSKGIIYRDLKLDNVMLDRDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFERDPDKRLGVTGNIRIHPFFKTINWSLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDKNLIDSMDQEAFHGFSFVNPKFEQFLDI",
    "output": "Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Negatively regulates B cell proliferation and also has an important function in self-antigen induced B cell tolerance induction . Upon DNA damage, activates the promoter of the death-promoting transcription factor BCLAF1/Btf to trigger BCLAF1-mediated p53/TP53 gene transcription and apoptosis. In response to oxidative stress, interact with and activate CHUK/IKKA in the nucleus, causing the phosphorylation of p53/TP53. In the case of ER stress or DNA damage-induced apoptosis, can form a complex with the tyrosine-protein kinase ABL1 which trigger apoptosis independently of p53/TP53. In cytosol can trigger apoptosis by activating MAPK11 or MAPK14, inhibiting AKT1 and decreasing the level of X-linked inhibitor of apoptosis protein (XIAP), whereas in nucleus induces apoptosis via the activation of MAPK8 or MAPK9. Upon ionizing radiation treatment, is required for the activation of the apoptosis regulators BAX and BAK, which trigger the mitochondrial cell death pathway. Can phosphorylate MCL1 and target it for degradation which is sufficient to trigger for BAX activation and apoptosis. Is required for the control of cell cycle progression both at G1/S and G2/M phases. Mediates phorbol 12-myristate 13-acetate (PMA)-induced inhibition of cell cycle progression at G1/S phase by up-regulating the CDK inhibitor CDKN1A/p21 and inhibiting the cyclin CCNA2 promoter activity. In response to UV irradiation can phosphorylate CDK1, which is important for the G2/M DNA damage checkpoint activation . Can protect glioma cells from the apoptosis induced by TNFSF10/TRAIL, probably by inducing increased phosphorylation and subsequent activation of AKT1. Can also act as tumor suppressor upon mitogenic stimulation with PMA or TPA (By similarity). In N-formyl-methionyl-leucyl-phenylalanine (fMLP)-treated cells, is required for NCF1 (p47-phox) phosphorylation and activation of NADPH oxidase activity, and regulates TNF-elicited superoxide anion production in neutrophils, by direct phosphorylation and activation of NCF1 or indirectly through MAPK1/3 (ERK1/2) signaling pathways . Involved in antifungal immunity by mediating phosphorylation and activation of CARD9 downstream of C-type lectin receptors activation, promoting interaction between CARD9 and BCL10, followed by activation of NF-kappa-B and MAP kinase p38 pathways . May also play a role in the regulation of NADPH oxidase activity in eosinophil after stimulation with IL5, leukotriene B4 or PMA. In collagen-induced platelet aggregation, acts a negative regulator of filopodia formation and actin polymerization by interacting with and negatively regulating VASP phosphorylation. Downstream of PAR1, PAR4 and CD36/GP4 receptors, regulates differentially platelet dense granule secretion; acts as a positive regulator in PAR-mediated granule secretion, whereas it negatively regulates CD36/GP4-mediated granule release. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin. The catalytic subunit phosphorylates 14-3-3 proteins (YWHAB, YWHAZ and YWHAH) in a sphingosine-dependent fashion . Phosphorylates ELAVL1 in response to angiotensin-2 treatment (By similarity). Phosphorylates mitochondrial phospholipid scramblase 3 (PLSCR3), resulting in increased cardiolipin expression on the mitochondrial outer membrane which facilitates apoptosis (By similarity). Phosphorylates SMPD1 which induces SMPD1 secretion (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQEKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDLPDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHIYSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNGNGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVKFIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAGPSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQQNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLDLIKEYYVPYMSNVNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWDDYKKELEKYGLSDYLAIKQKYYDQYQANKN",
    "output": "Part of the ABC transporter complex FusABC-MsmK involved in short- and long-chain fructooligosaccharide (FOS) import. Required for the utilization of long-chain FOSs . Binds kestose, nystose, fructofuranosyl-nystose and inulin, but not sucrose. Has a preference for long-chain FOSs (tetrasaccharides and larger) ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQFPHGQKGQHYFGQKDQQHTKSKGSFSIQHTYHVDINDHDRTRKSQQYDLNALHKATKSKQHLGGSQQLLNYKQEGRDHDKSKGHFHMIVIHHKGGQAHRGTQNPSQDQGNSPSGKGLSSQYSNTEKRLWVHGLSKEQASASGAQKGRTQGGSQSSYVLQTEELVVNKQQRETKNSHQNKGHYQNAVDVREEHSSKLQTSLHPAHQDRLQHGSKDIFTTQDELLVYNKNQHQTKNLNQDQEHGQKAHKISYQSSRTEERQLNHGEKSVQKDVSKGSISIQTEKKIHGKSQNQVTIHSQDQEHGHKENKMSHQSSSTEERHLNCGEKGIQKGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYRSSSTEERRLNSGEKDVQKGVSKGSISIQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTE",
    "output": "Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARRLSLLAVVLAMVAAVSASTAAAQSCGCASDQCCSKWGFCGTGSDYCGTGCQAGPCDVPATNDVSVASIVTPEFFAALVAQADDGCAAKGFYTRDAFLTAAGGYPSFGRTGSVDDSKREIAAFFAHANHETIKFCYIEEIDGPSKNYCDETSTQWPCMAGKGYYGRGPLQISWNFNYGPAGQSIGFDGLGDPDAVARSPVLAFQTALWYWTNNVHDAFVSGQGFGATIRAINGALECDGKNPTAVSNRVAYYQQFCQQFGVDPGSNLTC",
    "output": "May function in reproductive organs during embryogenesis and seed maturation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMAKKPPKPAPRRIFQERLKITALPLYFEGFLLVKRSDHQEYKHYWTELRGTTLFFYTDKKSTIYVGKLDIIDLVCLTGQHSTEKNCAKFTLVLPKEEVHVKTENTESGEEWRGFILTVTELTVPQHVSLLPGQVIRLHEVLEREKKRRIETDQLPLMPPEKEKEPVQDYADVLNPLPECFYAVSRKEATAMLEKNPSWGNMILRPGSDSKNYSITIRQEIEMPRIKHFKVTRTGNNYTIELEKPVTLPNLFSVIDYFVKETRGNLRPFIHSADDNFGQDPNIEDRSEKFKKNPHNA",
    "output": "May function as an adapter molecule downstream of KIT in the proliferation or differentiation of hematopoietic stem cells."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSILVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRSEIDLADIDYIIINHAEEDHAGALTELMAQIPDTPIYCTANAIDSINGHHHHPEWNFKVVKTGDTLDIGDGKQLIFVETPMLHWPDSMMTYMTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGINEVDPNVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDLDALELCRQHGRDIARQWALAPLPETTQKTAPVEETTTCTAADLGPKMQCSVCQWIYDPALGEPLQDVAPGTPWSDVPDNFLCPECSLGKDVFDVLATEAK",
    "output": "Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAEIMADSELAPKFAPFIGMAGIAAAMIFGSAGAAYGTAKSGIGIAGVGTFRPDLIMKCLIPVVMSGIIAVYALVVAVLIAQDLGPPGSGQHYSLFNGFMHLACGLSVGLTGLAAGYCIGIVGDKGVRSFMLQSRIFVGMVLILIFGEVLGLYGLIVALILNTKSKG",
    "output": "Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKYLLPVLVLCLGYYYSTNEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTMEDMAFAERFVVEAGKLLGGLDMLILNHITQTTMSLFHDDIHSVRRSMEVNFLSYVVLSTAALPMLKQSNGSIAIISSMAGKMTQPLIASYSASKFALDGFFSTIRKEHLMTKVNVSITLCVLGFIDTETALKETSGIILSQAAPKEECALEIIKGTVLRKDEVYYDKSSWTPLLLGNPGRRIMEFLSLRSYNRDLFVSN",
    "output": "Controls the reversible conversion of biologically active glucocorticoids such as 11-dehydrocorticosterone to corticosterone using NADP(H) . Participates in the corticosteroid receptor-mediated anti-inflammatory response, as well as metabolic and homeostatic processes (By similarity). Bidirectional in vitro, predominantly functions as a reductase in vivo, thereby increasing the concentration of active glucocorticoids . It has broad substrate specificity, besides glucocorticoids, it accepts other steroid and sterol substrates . Interconverts 7-oxo- and 7-hydroxy-neurosteroids such as 7-oxopregnenolone and 7beta-hydroxypregnenolone, 7-oxodehydroepiandrosterone (3beta-hydroxy-5-androstene-7,17-dione) and 7beta-hydroxydehydroepiandrosterone (3beta,7beta-dihydroxyandrost-5-en-17-one), among others (By similarity). Catalyzes the stereo-specific conversion of the major dietary oxysterol, 7-ketocholesterol (7-oxocholesterol), into the more polar 7-beta-hydroxycholesterol metabolite . 7-oxocholesterol is one of the most important oxysterols, it participates in several events such as induction of apoptosis, accumulation in atherosclerotic lesions, lipid peroxidation, and induction of foam cell formation (By similarity). Mediates the 7-oxo reduction of 7-oxolithocholate mainly to chenodeoxycholate, and to a lesser extent to ursodeoxycholate, both in its free form and when conjugated to glycine or taurine, providing a link between glucocorticoid activation and bile acid metabolism (By similarity). Catalyzes the synthesis of 7-beta-25-dihydroxycholesterol from 7-oxo-25-hydroxycholesterol in vitro, which acts as ligand for the G-protein-coupled receptor (GPCR) Epstein-Barr virus-induced gene 2 (EBI2) and may thereby regulate immune cell migration (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKTFVAETVKRDWYVVDAAGKTLGRLATELASRLRGKHKAEYTPHVDTGDYIIVINAEKVVVTGKKETDKIYYWHTGYVGGIKDATFKEMISRRPEAVIEIAVKGMLPKGPLGRDMFRKLKVYAGNTHNHAAQQPQVLDI",
    "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVSTTLATITIMSTLVGYTTGPLTDYMWLLIVGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETLGSVLLGAKVSETIRKGIIDVTMYKDIEHVLMAGSVSAMFGSAVWQLAASFLKLPISGTHCIVGATIGFSLVAKGQQGVKWLELLRIVASWFLSPLLSGVMSAVLFYFVRMFILQKKDPVPNGLRALPFFYAVTMGINLFSIMFTGAPMLGFDKLPWWGVLLISIGFGIITALIVWFAVCPRLKKKIECEVKSSSPSESPLMEKRELHEAHSPILKPVPEESSVLSSSTPTTPPLPPPEERRVTFDIGDSDDADQKDCKESDLGGAPKTAHVHFTNGPAHIPSNGYSQYHTVHKDSGLYKDLLHKLHLAKVGDCMGEGGDRPIRRNNSYTSYTMAIIGMHGDFKPKESEFRASEDGDKEKAGAQERKRIRMDSYTSYCNAVAENGTPEDLGEGEVTLEMVDEDAGSSRSSLEEDRTDADKPEVSMLFQFLQILTACFGSFAHGGNDVSNAIGPLVALWLVYESGSVISSAPTPIWLLLYGGVGICVGLWVWGRRVIQTMGRDLTPITPSSGFSIELASAVTVVVASNIGLPVSTTHCKVGSVVAVGWLRSRKAVDWRLFRNIFMAWFVTVPISGLISAAIMALFNYVIL",
    "output": "Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE",
    "output": "RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQGRLSSWLVKHGLIHRSLGFDYQGIETLQIKPEDWHSIAVILYVYGYNYLRSQCAYDVAPGGLLASVYHLTRLEYGIDQPEEVCIKIFVARKNPRIPSIFWVWKSADFQEKESYDMLGISYDNHPRLRRILMPESWIGWPLRKDYIAPNFYEIQDAH",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQFAPLLLGVFLLCGSARGSDSSASNAITCFTRGLDLRKETEDVLCPANCPLWQFYVFGDGIYASLSSVCGAAIHRGVITNAGGAVRVQTLPGQENYPAVHANGIQSQVLSRWASSFSVTPGTNNLALEAVGRSVATARPATGKRPKKTLEKKAGNKDCKADIAFLIDGSYNIGQRRFNLQKNFVGKVAVMLGIGTEGPHVGVVQASEHPKIEFYLKNFTAAKEVLFAIKELGFRGGNSNTGKALKHAAQKFFSMENGARKGIPKIIVVFLDGWPSDDLEEAGIVAREFGVNVFIVSVAKPTTEELGMVQDIGFIDKAVCRNNGFFSYQMPSWFGTTKYVKPLVQKLCSHEQMLCSKTCYNSVNIGFLIDGSSSVGESNFRLMLEFISNVAKAFEISDIGSKIATVQFTYDQRTEFSFTDYTTKEKVLSAIRNIRYMSGGTATGDAISFTTRNVFGPVKDGANKNFLVILTDGQSYDDVRGPAVAAQKAGITVFSVGVAWAPLDDLKDMASEPRESHTFFTREFTGLEQMVPDVIRGICKDFLDSKQ",
    "output": "Plays a role in the control of cell shape and motility in the trabecular meshwork."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTENNDIKMVIITGMSGAGKTVALQSFEDLGYFCVDNLPPMLLPKFVELMADSKSKMNKVALGIDLRGREFFEHLWGALDDLSERTWIIPHILFLDAKDSTLVTRYKETRRSHPLAPTGLPLKGIEAERGLLTDMKARANIVLDTSDLKPKELREKIVQLFSTETEQAFRVNVMSFGFKYGIPIDADLVFDVRFLPNPYYIPHMKPLTGLDEEVSSYVLKFNETHKFLEKLTDLITFMLPHYKREGKSQLVIAIGCTGGQHRSVTLAEYLGKHLKPDYSVHVSHRDVEKRKGH",
    "output": "Displays ATPase and GTPase activities."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASAVRGSRPWPRLGLQLQFAALLLGTLSPQVHTLRPENLLLVSTLDGSLHALSKQTGDLKWTLRDDPVIEGPMYVTEMAFLSDPADGSLYILGTQKQQGLMKLPFTIPELVHASPCRSSDGVFYTGRKQDAWFVVDPESGETQMTLTTEGPSTPRLYIGRTQYTVTMHDPRAPALRWNTTYRRYSAPPMDGSPGKYMSHLASCGMGLLLTVDPGSGTVLWTQDLGVPVMGVYTWHQDGLRQLPHLTLARDTLHFLALRWGHIRLPASGPRDTATLFSTLDTQLLMTLYVGKDETGFYVSKALVHTGVALVPRGLTLAPADGPTTDEVTLQVSGEREGSPSTAVRYPSGSVALPSQWLLIGHHELPPVLHTTMLRVHPTLGSGTAETRPPENTQAPAFFLELLSLSREKLWDSELHPEEKTPDSYLGLGPQDLLAASLTAVLLGGWILFVMRQQQPQVVEKQQETPLAPADFAHISQDAQSLHSGASRRSQKRLQSPSKQAQPLDDPEAEQLTVVGKISFNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNVLRYFCTERGPQFHYIALELCRASLQEYVENPDLDRGGLEPEVVLQQLMSGLAHLHSLHIVHRDLKPGNILITGPDSQGLGRVVLSDFGLCKKLPAGRCSFSLHSGIPGTEGWMAPELLQLLPPDSPTSAVDIFSAGCVFYYVLSGGSHPFGDSLYRQANILTGAPCLAHLEEEVHDKVVARDLVGAMLSPLPQPRPSAPQVLAHPFFWSRAKQLQFFQDVSDWLEKESEQEPLVRALEAGGCAVVRDNWHEHISMPLQTDLRKFRSYKGTSVRDLLRAVRNKKHHYRELPVEVRQALGQVPDGFVQYFTNRFPRLLLHTHRAMRSCASESLFLPYYPPDSEARRPCPGATGR",
    "output": "Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVIDRAGYRLNVGIILVNDSDRVFWGRRSGHDAWQFPQGGLAPGETAMQAMYRELHEEVGLDKGDVEILGSTRRWLKYRLPKQYLRHGSEPLVIGQKQKWYLLKLVTSEQKVRLDLSDSPEFDSWRWVDFHEPEQQVIFFKRQVYIQALKELEPLLKKERRTPYGLKRKRGNQRA",
    "output": "Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVAITSLAQSLEHLKRKDYSCLELVETLIARCEAAKSLNALLATDWDGLRRSAKKIDRHGNAGVGLCGIPLCFKANIATGVFPTSAATPALINHLPKIPSRVAERLFSAGALPGASGNMHELSFGITSNNYATGAVRNPWNPDLIPGGSSGGVAAAVASRLMLGGIGTDTGASVRLPAALCGVVGFRPTLGRYPGDRIIPVSPTRDTPGIIAQCVADVVILDRIISGTPERIPPVPLKGLRIGLPTTYFYDDLDADVALAAETTIRLLANKGVTFVEANIPHLDELNKGASFPVALYEFPHALKQYLDDFVKTVSFSDVIKGIRSPDVANIANAQIDGHQISKAEYELARHSFRPRLQATYRNYFKLNRLDAILFPTAPLVARPIGQDSSVIHNGTMLDTFKIYVRNVDPSSNAGLPGLSIPVCLTPDRLPVGMEIDGLADSDQRLLAIGGALEEAIGFRYFAGLPN",
    "output": "Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNRKETRKVKVGNIYVGGDFRVSIQSMTNTDTKDVESTVKQIKELQEAGCDIVRCAVLDMDAACAIKDIVAKINIPLVADIHFDYRLALKAIENGVSAIRINPGNIGSREKVEAVVKACKEKNIPIRIGVNSGSLSKELLTKYGKPTPDALVESALEHVKILEELDFHDIVISMKSSNVETMIESYRIASQKTNYPLHLGVTEAGTPWRGTIKSAIGIGTLLAEGIGDTIRVSLTGDPVEEIKVGKEILKNFGYVKEGIEFISCPTCGRTQIDLINIAKEVEERLSSCKKNIKVAVMGCVVNGPGEAREADIGIAGGKGEGLIFRKGEIIKKVKEEDLVEELIKIIETI",
    "output": "Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKNEYLLLTPGPLSTSETVREAMLKDWCTWDDEYNKDIVEVIRTKLVKLATQQDGYTSVLMQGSGTASVEATIGSAIAKEGKLLVVDNGAYGARIAQIADYLNIPCHVVSPGETSQPHLNEVETALASDPAITHVAIVHCETTTGMLNPIEAFASVAKAHGKVVILDAMSSFGGIPIDIAELGIDFMISSANKCIQGVPGFGFVIAKQTELEKCQGQARSLSLDLYDQWHCMEVNHGKWRFTSPTHTVRAFYQALLELEQEGGIEARHNRYQTNQKTLVAGMRSLGFEPLLNDELHSPIITSFYSPTHSDYQFKAFYTRLKEQGFVIYPGKVSNADCFRIGNIGEVYPADIERLIGAIEKAMYWQVA",
    "output": "Involved in phosphonate degradation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGHGSQNESLMSVIEYKGNPSEDARPVVLVGKGLTFDSGGISIKPAEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMSNHNPLAHELISASEQAGDRAWRLPLGDEFQEQLESNFADIANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLSQFLLNRAGFNGEE",
    "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNTLFIADLHLSAQEPAITAGFLRFLRQDAIHADALYILGDLFEAWIGDDDPEPLHGEIAAALKALQQAGVPCYFIHGNRDFLVGKRFARTSGMQLLPEEQVLDLYGRKILILHGDTLCTDDQAYQQFRRKVHNPLIQKLFLAMPLRWRLKIAAKMRARSQQSNQYKSDSIMDVNPQAVEQAMLRHKVHWMIHGHTHRPAVHELALSNGKAHRVVLGAWHVEGSMIKVSADAVELIQFPF",
    "output": "Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMGRVPDGPTGLAALVPSVEEAQAMLPPRRLRLLLSIAAVVLTLDIVTKVLAVKFLLPGKSVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIATGVVIGIFWMGRRLVSSWWALGLGMILGGAMGNLVDRFFRAPAPLRGHVVDFLSIGWWPVFNVADPSVVVGAILLVVLSIFGFDFDTVGRRKAEFDIAGQRKAEQR",
    "output": "This protein specifically catalyzes the removal of signal peptides from prolipoproteins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEAVPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDGRAATPHLLHHRLPLPDDREDGELEEGELEDDGAEEVQDPPGGQERSRKEKGEKHHSDSEEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKSHRKYRDYSPPYAPSHQQYSSSHNAPLPKKSYSKMDSKGYSMYEDYENEQYGEYEGDEEEDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGEHPEDEEDLYEEEIEYGESEEPMGDDDYDDYSKELNQYRRSKDSRGRGLSRGRGRGSRGGRGKGMGRGRGRGGRGGMSKGGMNDDEDFYDDDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHGDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMSLPTHEPLSPQQLQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPSGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYPQQEGMEMEPGLVGDAEDYGHYEELPGQPGEPLFPEHPLEPDSFPEGGPPGRPKAGAGVPDFLPSAQRALYLRIQQKQQEEERARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASVGEPSSSGLGDPRLQKGHPTGSRLSDPRLSRDPRLSRHAETSGGSGPGDSGPSDPRLARALPTSKAEGSLHSSPAGPSSSKGQPPAEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDVPPVPAALQSLPALDPRLHRSTPPGPPNTRQRPGSTDPSTSGSNLPDFELLSRILKTVNVNTPGQSEKPSDPRVRKTPTDPRLQKPADPVAASRAAKPCPTEASPPAASPSGDSSPPATAPYDPRVLAAGGLGQGSSSGQSSVLSGISLYDPRTPNAGGKTAEPASDTSAQPKGPEGNGKGSASKAKEPPFVRKSALEQPETGKASTDGATATDRYNSYNRPRPKATAAPTAASSTPPPEGATPQPGVHNLPVPTLFGTVKPAPKTGTGSPFAGNSPAREGEQDAGSLKDVFKGFDPTASPFCQ",
    "output": "RNA-binding protein that suppresses transcription of long non-coding RNAs (lncRNAs) . LncRNAs are defined as transcripts more than 200 nucleotides that are not translated into protein . Together with WDR82, part of a transcription termination checkpoint that promotes transcription termination of lncRNAs and their subsequent degradation by the exosome . The transcription termination checkpoint is activated by the inefficiently spliced first exon of lncRNAs ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKPTVVSADVLFEDHRAALKWQWVAGLGASERRFDEVAVRAARSGADLVGYLNYIHPYRVQILGEREVAYLTNESPDDCARRISRIITLEPPVLVVADDQTAPDTLLSMCERAQLPMFATPESAAFVIDVLRAYLSKHFADRTSMHGVFMDILGMGVMITGESGLGKSELGLELISRGHGLVADDAVDLYRINQTTIEGRCPELLQNLLEVRGIGLLDIKAIFGETAVRRKMRLKMIVHLVRRETLERDYERIPYEPLTQDVLGIPVRKVIIQVEAGRNIAVLVEAAVRNAILQLRGINTYQEFVERHRKAMEQDD",
    "output": "Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNSVSAAERLKSFGDAGPVCNKSIIFPSRVVTLANSFEKKDRSWYVKSQIPTDLSIQVNDITFKAHKFPLISKCGYISSIELKPSTSENGYHLKLENFPGGADTFETILKFCYNLPLDLNPLNVAPLRCASEYLYMTEEFEAGNLISKTEAFITFVVLASWRDTLTVLRSCTNLSPWAENLQIVRRCCDLLAWKACNDNNIPEDVVDRNERCLYNDIATLDIDHFMRVITTMKARRAKPQITGKIIMKYADNFLPVINDDLEGIKGYGLGKNELQFSVNRGRMEESNSLGCQEHKETIESLVSVLPPQSGAVSCHFLLRMLKTSIVYSASPALISDLEKRVGMALEDANVCDLLIPNFKNEEQQERVRIFEFFLMHEQQQVLGKPSISKLLDNYLAEIAKDPYLPITKFQVLAEMLPENAWKCHDGLYRAIDMFLKTHPSLSDHDRRRLCKTMNCEKLSLDACLHAAQNDRLPLRTIVQINTQVLFSEQVKMRMMMQDKLPEKEEENSGGREDKRMSRDNEIIKTLKEELENVKKKMSELQSDYNELQQEYERLSSKQKSSHNWGLRWQKVKKSFQTKREDEETRERTRRRSSTGQRTSFRRRMSMS",
    "output": "May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in leaf vasculature patterning ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAAAGQEKGYLTQTAAALDKSPSLSPQLAAPIRGRPKKCLVYPHAPKSSRLSRSVLRWLQGLDLSFFPRNINRDFSNGFLIAEIFCIYYPWELELSSFENGTSLKVKLDNWAQLEKFLARKKFKLPKELIHGTIHCKAGVPEILIEEVYTLLTHREIKSIQDDFVNFTDYSYQMRLPLVSRSTVSKSIKDNIRLSELLSNPNMLTNELKAEFLILLHMLQRKLGRKLNPEWFDVKPTVGEVTLNHLPAQASGRRYNLKVKRGRVVPVLPNIGSGGSSHREIHVKQAGQHSYYSAMKPIRNMDKKP",
    "output": "May play a role in apoptosis regulation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMKAEAAGSLPKTNAEAVRKKPGRKRYGWMKGLLLPAVIIAIWQVIGGLGVVSATVLPTPVTIVLTFKELILSGELFGHLQISIYRAALGFLLGAGLGLMIGILAGFSKRTELYLDPSLQMLRTVPHLAVTPLFILWFGFDEVSKILLIALGAFFPVYINTFNGIRGVDAKLFEVARVLEFKWHQQISKVILPAALPNILLGIRLSLGIAWLGLVVAELMGSSSGVGYMIMDARQFSQTNKVFAGIIIFAVVGKLTDSFVRLLERKLLKWRNSYEG",
    "output": "Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKVKTLSGNRIKSNQISKLQKEFRRHNSDAHSTTSSASPAQSPCYSNQSDDGSDTEMASGSNRTPVFSFLDLTYWKRQKICCGIIYKGRFGEVLIDTHLFKPCCSNKKAAAEKPEEQGPEPLPISTQEW",
    "output": "Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway. Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is crucial for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMNFSDPCLLGPSACNEDFFEELAREILPTPEAKALAARLLRRLGWHPSEGQCSWCPEAYEYLYDLQFRYTGPVPLVRKHPGSALIVRWMLDGLGHFLFCRPRVQGNPLTYHLSCMGSAIRTLELFREQAHSHLWEQGNLVDCYWSCSSDYGYEGKWGQQAVVRGALSGPWPRPDPPSLQLQCLCAIWRTCLLRGQSQAQKYTNWICARHLQLRPDTSTRDSDLLLQRC",
    "output": "Inhibits host NF-kappa-B activation stimulated by IL-1 and multiple PRR viral detection pathways. Targets host NF-kappa-B component RELA/p65 for ubiquitin-dependent proteasomal degradation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKGKFIVIEGLEGAGKSTAVNTVQQFLRHFKIQDVICTREPGGTALSEEIRHLIKKKSQNEEILTDKAELLLLYAARVQLLENIIKPALSSGTWVIGDRHDLSSQAYQGGGRGIKSEFIKSLADFTLGSSFRPDLTLYLDLPPELGLQRARKRGHLDRIEQQSLVFFERIRARYLELTYDDPRIKMIDASKPIKKVTVDIQNALLSLLEK",
    "output": "Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSINKTLKIATRQSPLALWQANYVKNRLQQRYSHLSVELVPIITKGDVILDTPLAKIGGKGLFVKELENALLNGEADIAVHSMKDVPMQFPKGLELSVICPREDPRDAFVSNKYRTLDELPQGAIVGTSSLRRQCQLKNWRADLDIRSLRGNVGTRLNKLDQGDYDAIILASAGLIRLGLTERIRSFIEIDTILPACGQGAVGIECRVDDRDVQSLLMPLADQTTTYCVLAERAMNFHLQGGCQVPIGAYAILENNQLYLRGLVGDVHGSQILSAEGQFELSLDFESSQSAVQKAEELGVSIAEQLLQQGADKILQAVYQS",
    "output": "Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEVVQSVDPINFTEAASLKVKELIEEEGDNSLSLRVYITGGGCSGFQYAFAFDNEVKEDDMVITKNGVRLLVDSMSFQYLVGADVDYKDDVEGAYFVIRNPNAKTTCGCGSSFSV",
    "output": "Required for insertion of 4Fe-4S clusters for at least IspG."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MCAKSLLLVFGILLGLSHLSLSQNWATFQQKHIINTPIINCNTIMDNNIYIVGGQCKRVNTFIISSATTVKAICTGVINMNVLSTTRFQLNTCTRTSITPRPCPYSSRTETNYICVKCENQYPVHFAGIGRCP",
    "output": "Preferentially cleaves single-stranded RNA at pyrimidine residues with a 3'flanking guanine. Hydrolyzes poly(U) and poly(C) as substrates, and prefers the former. The S-lectins in frog eggs may be involved in the fertilization and development of the frog embryo. This lectin agglutinates various animal cells, including normal lymphocytes, erythrocytes, and fibroblasts of animal and human origin. It is cytotoxic against several tumor cells."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "DSTDGLLVKDKYLCGDLYGEEYGVIFPYLGLKTECLWTIKMDPLYRILLTVRDVHENCNKESLEIIEGPPESSNSRKICDTSHAEYTSCTNTMTVKYTRKPNHPAPDFFLIFRRVL",
    "output": "May be involved in the fertilization process."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQIHRLPAFSDNYIFVLHDPGQNIAAVVDPADPQPVLKKLAELGAELVAIFNTHHHSDHVGGNRTLLQAFPNTVVYGGEQDRGRIPGQQHFLKEGDQVSFAHRRAEVYFVPGHTRAHIAYYFPPTTGEEWGELFCGDTLFAGGCGRLFEGTPAQMVDSLSKLRNLPETTRVWCAHEYTLKNLQFALTVDSDNSHLKNRFKQVQNARNLSQPTVPSDIGLEKQTNPFLRWDQPHLIIHTKSNTPVQCFARLRGMKDQF",
    "output": "Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQQGLFTADPRNNPQAELIKDVHGIDDALRAIAGDSVSGLGTGGMGTKLQAADVACRAGIDTIIAAGSRPGVIGDVMEGISVGTLFHAEATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVTRYNSDALRRIAGHHSQQIDAILGYEYGPVAVHRDDMIIR",
    "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQIRTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLLFASQHQGRMHACGHDFHMTIALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPDQFYGLHVRPDLKVGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVVASYFVTQVQSVVSRNVNPIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFDMEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDGVMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE",
    "output": "Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVTGLSPLLFRKLSNPDIFAPTGKVKLQRQLSQDDCKLRRGSLASSLSGKQLLPLSSSVHSSVGQVTWQSTGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKSLIVTSSTSPTLPRPHSPLHGHTGNSPLDSPRNFSPNAPAHFSFVPARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADELHFLTKHFSTENVPDEEGRRSPRMRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKATAQMEERPSLTFISSNTPDSVLPLADGALSFIHHQVIEMARDCLDKSRSGLITSHYFYELQENLEKLLQDAHERSESSDVAFVIQLVKKLMIIIARPARLLECLEFDPEEFYHLLEAAEGHAKEGHGIKCDIPRYIVSQLGLTRDPLEEMAQLSSYDSPDTPETDDSVEGRGVSQPSQKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDDALPPDAQDLTSKLLHQNPLERLGTSSAYEVKQHPFFMGLDWTGLLRQKAEFIPQLESEDDTSYFDTRSERYHHVDSEDEEEVSEDGCLEIRQFSSCSPRFSKVYSSMERLSLLEERRTPPPTKRSLSEEKEDHSDGLAGLKGRDRSWVIGSPEILRKRLSVSESSHTESDSSPPMTVRHRCSGLPDGPHCPEETSSTPRKQQQEGIWVLIPPSGEGSSRPVPERPLERQLKLDEEPPGQSSRCCPALETRGRGTPQLAEEATAKAISDLAVRRARHRLLSGDSIEKRTTRPVNKVIKSASATALSLLIPSEHHACSPLASPMSPHSQSSNPSSRDSSPSRDFLPALGSLRPPIIIHRAGKKYGFTLRAIRVYMGDTDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELVLKSGNKVSISTTPLENTSIKVGPARKGSYKAKMARRSKRSKGKDGQESRKRSSLFRKITKQASLLHTSRSLSSLNRSLSSGESGPGSPTHSHSLSPRSPPQGYRVAPDAVHSVGGNSSQSSSPSSSVPSSPAGSGHTRPSSLHGLAPKLQRQYRSPRRKSAGSIPLSPLAHTPSPPATAASPQRSPSPLSGHGSQSFPTKLHLSPPLGRQLSRPKSAEPPRSPLLKRVQSAEKLAAALAAAEKKLAPSRKHSLDLPHGELKKELTPREASPLEVVGTRSVLSGKGPLPGKGVLQPAPSRALGTLRQDRAERRESLQKQEAIREVDSSEDDTDEEPENSQATQEPRLSPHPEASHNLLPKGSGEGTEEDTFLHRDLKKQGPVLSGLVTGATLGSPRVDVPGLSPRKVSRPQAFEEATNPLQVPSLSRSGPTSPTPSEGCWKAQHLHTQALTALCPSFSELTPTGCSAATSTSGKPGTWSWKFLIEGPDRASTNKTITRKGEPANSQDTNTTVPNLLKNLSPEEEKPQPPSVPGLTHPLLEVPSQNWPWESECEQMEKEEPSLSITEVPDSSGDRRQDIPCRAHPLSPETRPSLLWKSQELGGQQDHQDLALTSDELLKQT",
    "output": "Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAERTHACGKVTVEAVGQTVQLKGWVQKRRDLGGLIFIDLRDRTGIVQVVFNPETSKEALEVAETIRSEYVLHVEGTVVERGEGAINDNMATGRIEVQATKVNVLNAAKTTPIIIADDTDASEDVRLKYRYLDLRRPVMFNTFKMRHDVTKTIRNFLDTEEFLEVETPILTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMVGGFERYYQVARCFRDEDLRADRQPEFTQIDIEASFLTQDEILDMMERMMTKVMKDAKGVEVSAPFPRMKYADAMARYGSDKPDTCFEMELTDLSEFAADCGFKVFTSAVESGGQVKAINAKGAASKYSRKDIDALTEFVKVYGAKGLAWLKVEEDGLKGPIAKFFGEEDANVLMSTLEATAGDLLLFVADKKSVVADSLGALRLRLGKELELIDESKFNFLWVTDWPLLEYDEDADRYFAAHHPFTMPFREDVELLETAPEKARAQAYDLVLNGYELGGGSLRIYERDVQEKMFKALGFSQEEAQEQFGFLLEAFEYGTPPHGGIALGLDRLVMLLAGRTNLRDTIAFPKTASASCLLTEAPSPVAEAQLEELNLKLSLKEEK",
    "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMRQSLQAVLPEISGNKTSLLRKSVCSDLLTLFNSPHSALPSLLVSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIMLYHDDEPLTFDLVWDNGGWRSATLENVS",
    "output": "Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLDREGFRPNVGIVLLNQRNQVFWGKRIRTHSWQFPQGGIKYGETPEQAMYRELHEEVGLQPEHVRILARTRDWLRYEVPDHYIRREARGHYRGQKQIWFLLQLTGRDNDMNLRACDHPEFDAWRWNEYWVPLEVVIDFKRDVYQMALTELARFLPRANHHNRYLRSGMRAHRREDEERSNGEAPMEAADGETTPEGPR",
    "output": "Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKILSVLLLALIICSIVGWSEAQFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS",
    "output": "This toxin inhibits numerous potassium channels: shaker (Ki=227 nM), Kv1.2/KCNA2 (nanomolar range), Kv1.3/KCNA3 (nanomolar range), Kv1.5/KCNA5 (Kd>100 nM), Kv1.6/KCNA6 (Ki=22 nM), KCa1.1/KCNMA1 (IC(50)=5.9 nM). It blocks channel activity by a simple bimolecular inhibition process. It also shows a weak interaction with nicotinic acetylcholine receptors (nAChR), suggesting it may weakly inhibit it . It also exhibits pH-specific antimicrobial activities against bacteria (B.subtilis, E.coli and S.aureus) and the fungus C.albicans ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MASTWAIQAHMDQDERLEVKIEEKKYTTRQDWDLHKNNTHSREVFRQYFRQFCYQETSGPREALSRLRELCHQWLRPETHTKEQILELLVLEQFLTILPEELQAWVQEQHPESGEEVVTVLEDLERELDEPGEQVSAHTGEHEMFLQKMVPLGKEGEPSMPLQSMKAQLKYESPELESQQEQVLDVETGNEYGNLKQEVSEEMKPHGNTSSKFENDMSQSARCGETHEPEEITEEPSACSREDKQPTCDENGVSLTENSDHTEHQRICPGEKSYGCDDCGKTFSQHSHLTEHQRIHTGDRPYKCEECGKAFRGRTVLIRHKIIHTGEKPYKCNECGKAFGRWSALNQHQRLHTGEKHYHCNDCGKAFSQKAGLFHHIKIHTRDKPYQCTQCNKSFSRRSILTQHQGVHTGAKPYECNECGKAFVYNSSLVSHQEIHHKEKCYQCKECGKSFSQSGLIQHQRIHTGEKPYKCEVCEKAFIQRTSLTEHQRIHTGERPYKCDKCGKAFTQRSVLTEHQRIHTGERPYKCDECGNAFRGITSLIQHQRIHTGEKPYQCDECGKAFRQRRKTSYKEILLKNHSEPQAGVNLLLSSLIPEWQSCCRKDL",
    "output": "May be involved in transcriptional regulation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME",
    "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGIARILSAVLFLSVLFVVTFPALLSADHHDGRIDTCRLPSDRGRCKASFECWYFNGRTCAKFIYGGCGGNGNKFPTQEACMKRCAKA",
    "output": "Toxin with inhibitory activity on serine proteases, but not on potassium channels . Is active against trypsin (Ki=0.281 nM), kallikrein (Ki=337 nM), and chymotrypsin ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPLMNPLNPWPLESSNPLIAVLVSGGIDSLVAAHLLKQSGADVTAIHFLTGYEPEDRAGRLEKLFTQMDIPVFIFDCRTVFQSNVVDYFTAAYLRGETPNPCMVCNSRIKFGACMDYARSLGADAVATGHYCRTTKDPDGVRLWKGADPAKEQSYFLAFLSQDQLGRARFPLERMTKDQVRAHAARHGLVPIESKESQDVCFIRGEECADFIEAQVPAIPGPGPIEDMTGRLIGTHSGLHRFTVGQRRGINCPAEQPYYVAALDMARNCLKVGFRQDLFVPVCRVAQVNWIPDRPKGSMNVSVKIRYNQTEVPARLTALGETDAVVEFVTPQFAVAPGQGAVFYDGDAVLGGGIIRAE",
    "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTDMYSLFVAFILGVVEGLTEFLPVSSTGHMIIVGELLGFTGDKAKTFEVIIQLGSILAVVVVFWRRLFGLIGIHFGAVPHEGKTNGHLTLGHILLAMIPAVILGLAFHDVIKALFDPKSVMYALVAGGVLLLAAEWLKPKNPKAVGLDDITYRQAFAIGCFQCLALWPGFSRSGATISGGMLVGVNRYAASEFSFILAVPMMIGASGLDLYKSLHFLTLGDLPMFAVGFITAFIVALIAIKTFLSLIKRISFVPFAIYRFIVAAVVYWVFM",
    "output": "Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLGVSGMQPRQLAAQILNFALVLSTAFMMWKGLSVVSDSSSPIVVVLSGSMEPAFQRGDLLFLWNRGLDTQVGEIVVYNVKGKDIPIVHRVVRRYGGGKTPLRLLTKGDNNIADDTELYATSQSFLTRKEDVVGSVVGFIPFVGYVTILLSENPWMKQVMLGLMGVMVVLQRE",
    "output": "Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MASERHHSIDAQLRALAPGKVSEELIQYDALLVDRFLDILQDLHGPSLREFVQECYEVSADYEGKKDTSKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVELAHRRRNSKLKHGDFSDEGSATTESDIEETLKRLVSLGKTPAEVFEALKNQSVDLVFTAHPTQSARRSLLQKNARIRNCLTQLSAKDVTVEDKKELDEALHREIQAAFRTDEIRRAQPTPQDEMRYGMSYIHETVWNGVPKFLRRVDTALKNIGINERLPYDVPLIKFCSWMGGDRDGNPRVTPEVTRDVCLLSRMMAANLYINQVEDLMFELSMWRCNDELRARAEEVQSTPASKKVTKYYIEFWKQIPPNEPYRVILGAVRDKLYNTRERARHLLATGFSEISEDAVFTKIEEFLEPLELCYKSLCECGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERQTDVIDAITTHLGIGSYRSWPEDKRMEWLVSELKGKRPLLPPDLPMTEEIADVIGAMRVLAELPIDSFGPYIISMCTAPSDVLAVELLQRECGIRQTLPVVPLFERLADLQAAPASVEKLFSTDWYINHINGKQQVMVGYSDSGKDAGRLSAAWQLYVAQEEMAKVAKKYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFMFGEENLCFQSLQRFTAATLEHGMHPPVSPKPEWRKLMEEMAVVATEEYRSVVVKEPRFVEYFRSATPETEYGKMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKWAIDKDIKNFQKLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPYLKQGLRLRNPYITTLNVFQAYTLKRIRDPSFKVTPQPPLSKEFADENKPAGLVKLNGERVPPGLEDTLILTMKGIAAGMQNTG",
    "output": "Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVVDDSAVVRQVVAGLLADDPAIEVIAAVADPILAIARMKVQWPDVFVLDIEMPRMDGITFLKKIMAERPTPVVICSTLTEKGAQTSMAALSAGAVAIITKPKLGLKQFLVDASDDLISAVKAAARANVKRLQVVEKLTADAILPASDRHDAMLQTTERVVALGTSTGGTQALEVVLTALPRVTPGIVIVQHMPEKFTAEFANRLNGLCQITVREAKNNDRVVPGRALIAPGGKHMLLRRNGAQYSVEVLDGPLVNRHRPSVDVLFRSVARCAGANALGVIMTGMGDDGAAGLAEMRKAGARTLAQDEESCVVYGMPKEAVKRGGVERSVPLGAIAREIMAQMAG",
    "output": "Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQETSLTKAVSPRQSLGQILLNYYQLTKPRLIVLFLITTAAGMWVAARGEVDPVLALITLLTGAMAAGSANTINCLYDRDIDYIMERTRHRPLPSGRVQPWEALVFAIALAVGAFSLQTLCANLLSACLEMAGIAVYVGVYTHWLKRSSTQNIVIGGAAGAIPPLVGWAAVTGELSWAAWVLFAIIFIWTPPHFWPLAMLIQEDYAKVNVPMMPVVDGDRPTAWQIFGYTLVLLPTTLLLVYPLHACGLIYGAIALVLGVVFIRKAWELVQTPEDKDQARAVFKFSILYMMILCAAMGIDSLPLTHAVVSQVTANLQTLVGTIL",
    "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKVGVALSGGVDSAVALYLLLKEGHEVKAFHMKTKEDEFFLKKEIKKKVCCSPSDTADAIRIARSLGVEIEIVDVREVFREKVIEPFKRDLLRGLTPNPCVHCNRYVKFGYFMDYVLSQGFDAFASGHYARVEFSGKYGKKVIKKGVDGKKDQSYFLARIEPWRIEKLLFPNGIYTKEEIRRIAEEAGIHVAKKQESQDVCFIPDGSIENFLKDEGITLSEGKVITEKGEVVGHHRGYPLYTVGQRKGLKIEKFGERLYVREKIPESNVVVVSGLEDVFFSGLIAEDPVWHVEVPEEFRCVCRVRKKSEEAPAVVRVRDNEVEVRFEKKVFAVTPGQIAAFYDEDTLLGGAIIKEGIR",
    "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDAVIDTSVIIEIFRGNKDTLYQICDYNCKITSITVFELYCGNLKENEMIMIDSLPKLNFDDKSSKIAGNIFKKLKKEGKIPSVKDLLIASIFY",
    "output": "Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB3 (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKFRSLADIRRDYGELQLSEESAENDPISQFKLWFDDVLLNEKNDPTAMVLSTVDEKGYPDSRVVLLKGLENGNFIFYTNYQSAKAMQIQKNPYAALNFYWPQMARQVRVRGRVKKISSEQSDAYFSSRPLKSQFSAIVSPQSQEILDRISLEDALNQLIEEYGQKPVVRPENWGGYMIIPDEIEFWQGRDNRLHDRIHYYRHGHEWTHRRLAP",
    "output": "Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL",
    "output": "Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTKHIKILVIGVGVAGPAVAYWLKRFGFSPVLIEKSAAVRKGGQALDIRGIATHIAKEMGIYDQICNMRTQIKCGRYVDVKGNVLHEEQGETFGFRQDDEVEILRGDLVEILMKAIADIPCEFKQSVIKIEQNEDSVTVTYKDGRVENYDLVIAADGIHSATRGMVFSKNEYQLINLGSYVSAFTIPNYLGLDHMELLCESNHKLVTLQSDSQADKAMAGFMFRSKHVLEDIRDEQEQKHFLHASFQNFGWETQNILNRMPESDDFYFDAITQIKMKSWTKGRIALIGDAAYCPSPLSGQGNNLAFVGAYILAGELKKADGDYIQAFTRYNELLHPFVEANQQFGVWVSESFLLKDDEVSKEIAEARSNKILAMIKSVSNSINLPQYE",
    "output": "An FAD-requiring monooxygenase active on tetracycline antibiotic and some of its derivatives, which leads to their inactivation . Expression in E.coli confers high resistance to tetracycline and oxytetracycline, does not confer resistance to minocycline or tigecycline. Degrades tetracycline and oxytetracycline; the reaction requires NADPH . Degrades and confers resistance to chlortetracycline ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYILIVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCGVPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA",
    "output": "Probably involved in ribonucleotide reductase function."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCVVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIRATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEAAEMEIDRILFEITAGALGKAPSKVTDALPEPEPSGAMAASDEEEEEEEALEAMQSRLATLRS",
    "output": "Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Selectively binds to phosphatidylinositol 3,5-bisphosphate PtdIns(3,5)P2 and PtdIns(3,4)P2 in preference to other phosphoinositides tested. Involved in late stages of cytokinesis. Plays a role in endosomal sorting/trafficking of EGF receptor (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR",
    "output": "Involved in resistance toward heavy metals."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTQLTHINTAGEAHMVDVSAKNETVREARAEAFVDMQAATLAMIIDGSHHKGDVFATARIAGIQAAKKTWELIPLCHPLLLTKVEVKLEAQPEHNRVRIETCCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMIIGPVRLLTKSGGKSGDFKVDI",
    "output": "Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVQKEMINKKISQDNSFIQNNNLADFDFLDAKKNSEIKTVSTGSLHLDEALGTGGLPLGRIVELYGNESSGKTTVALHAVASFQKAGKVACYIDAEGALDLSYAKAIGIDLGKLLVAHPKHGENAFALMESLIKTNKVALIVVDSVAALIPKQELEGNMDDQTIGLHARMMSKGLRRVQSLLPESDTCLLFINQLREKPGVMFGNGEVTTGGRALKFYASMRMEAKRSELLKDRFGNYVGIKSKLTVSKNKVARPFGVAFLEIMFNRGIVYEHEVIELALKHNVVVRSDNAYSFKSQNIAIGKEKLFSVLAEKPELFEQIKQLTIKQIHSPPPPAS",
    "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSAPTTSSSTDEDFAKPVKNGKTFANPKSFTNWGGIPGISDGFKFAFTETNHENVPCDKKILDVEIPVHNITADDFHSESDLFATWLGHATVLVDLEGVKFVTDPVWADRASFTSFAGPKRYRPPPMKLEDLPDLDFAVVSHDHYDHLDADAVKKITDRNPQIKWFVPLGMKKWMEGQGIGVDGSSTAVTELNWGESSEFVKNGKTYTIWCLPAQHWGQRGLFDRNHRLWSGWAVIGENRRFYYSGDTGHCDGEFKKFGEKLGPFDLAAIPIGAYEPRWFMKSQHINPEEAIEVHKLIRAKNSIGIHWGTYHMGSTEYYLEPRDKLKELMDAREDLKNTSFVTIEMGRIWEASDQ",
    "output": "D-type phospholipase that hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce bioactive N-acylethanolamines/fatty acid ethanolamides (NAEs/FAEs) and phosphatidic acid. NAEs are bioactive lipids that are involved in diverse physiological processes such as growth and lifespan."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRLDVVSKAARAAQRFSAQCHGQKFRTAHASATLRAALAVEASEANQKGRSAGLLAAMALMGVAGVASMDDNAAAKCEGAAKPVSREAVTQAMLKEVVTKLNRIESAVANPHRHTDGLNVGVDVVLGAQWGDEGKGKLVDSLSQSYDVIVRVAGGSNAGHTIVHEGKKYKFHLVPSGILNPNAICIIGNGVVVHLPSFLEELEELKRMGVDYEGRILISDRAHMVLDLHQEVDGINELRRGRNKIGTTKKGIGPAYSSKMLRNGVRVGDLRYFDDFTEKMVDLVKFYKDNYPELEADAEAEIKVYSDMKDKILDMTVDTVSYLNNAYVAGKKILVEGANATMLDIDFGTYPYVTSSNPSIGSVCTGGGISPNRLNGIIGIVKAYCTRVGEGPFPTELHDDVGEHLGTVGAEFGTTTGRARRCGWLDIPQMRYSNMVNGFTELNLTKLDVLTGLKKVKIGVAYWHEGKKLDGMPSNLQLLQDSVVEYEEMEGWSEDISKCKTFEELPVAAQKYVLRVEELLGTHIKWIGVGPDRFDVITRTHPLEKAYISGN",
    "output": "Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLYSLARPMLFSLAPERAHELTLSMLDKAHKLGMMRQTVEAKPTTCMGIEFPNPVGLAAGLDKNGAHIDALAGLGFGFIEIGTITPRPQSGNPKPRLFRIPEAKAIINRMGFNNDGVDKLIENVKASKFRGILGINIGKNADTPVEKAVDDYLICLEKVYNYASYITVNISSPNTKNLRSLQSGDALTELLQTLKARQLELAEQYNHYVPLVLKVAPDLTAEDVEFISAQLLDFKIDGLIVTNTTLSREGVENLPYGNESGGLSGAPVFEKSTECLRLFAQTLKGQIPLIGVGGILSGEQAAAKQQAGATLVQIYSGLIYTGPTLVKQCVEAMT",
    "output": "Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKTKTDFLKMKEQGEPITMLTAYDYPSAKLAEEAEVDMILVGDSLGMVVLGYDSTVPVTVEDMIHHTKAVRRGAKETFIVTDMPFMSYHVSLQETMMNARRIVQESGAHALKVEGAGEVISTIQYLTNAGIPVVAHLGLTPQSVGVLGGYKVQGKDAESAKKLIEDAKKCEEAGAIALVLECVPMQLAELISEQLTIPTIGIGAGQKVDGQVLVYHDLISYGVNRVPKFVKQYTSVQEEIVRGISQYVTEVKTRQFPEEKHSFTMKEEDRLALYGGKQ",
    "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKQRIHLYDHHVGLVVEQLRCITEGKSTDVDFLLRVKQQYTQLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERPFRTLPRPLAKDFFPERGWSHLLGKVLSDLPLRLPWQNKARDIGYIIASLQEALGEELLATCHLQVANELFYRNKAAWLVGKLVMPMATLPFLLPIHRSEEGELFVDTCLTTHAEASIVFGFARSYFMVYAPLPGALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLHYITRCDEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDRFAPQKEMTAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIAPALLALLQAEAGNKLTDLGDRIVISHLYIERRMVPLNLWLEQVNGQALRDAVEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFREIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLLRADYWRALQMRIKNGHVEDVYAYRRKQRFSVRYGADSRPDKAFTPPSGKVRRSA",
    "output": "Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSERSYYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKGNKESEEKFKEATEAYEILRDPKKRQAYDQFGKAGVGAGAGGFGQGAYTDFSDIFGDFGDIFGDFFGGGRGGFGGGRRSGSQRGSDLRYNLEVSLEDAALGREYKIEIPRLESCGDCNGSGAAKGSSPTTCPDCGGSGQIRRTQGFFSVATTCPTCRGKGTTISNPCKTCGGQGLQEKRRTINIKIPPGVETGSRLKVSGEGEAGPNGGSHGDLYVVTHIKRHELFERQGNDLILVRKITLAQAILGAEIEVPTIDGKKAKMKIPEGTESGQVFRLKGHGMPYLGAYGKGDQHVVVKIEIPKKITRRQRELIEAFARESGENIPGSKGKIFTK",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSRISDAFQKRKSLIAYITVGYPDIETTLRLVPLLEENGVDIIELGIPFSDPLADGVTIQNASYQALQNGVTPEVCLSVAALLKEKISIPMVFMGYYNPIYNYGLTKFCQKCATAGVSGFIIPDLPPGEAQDIDFAATEAGLDIIFLLAPTSTDERIKLVAAKSRGFIYLVSHSGVTGATANLPADLSSFVNRVRKTARQPLAVGFGISTPEQAQNIAKFSDGIIVGSRILQLVQTDPSLEKVATFIRQLRQSLD",
    "output": "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGKRERSEVYSEAVKRIL",
    "output": "Toxic component of a type II toxin-antitoxin (TA) system . A sequence-specific, ribosome-dependent mRNA endoribonuclease that inhibits translation during amino acid starvation (the stringent response). In vitro acts by cleaving mRNA with high codon specificity in the ribosomal A site between positions 2 and 3. The stop codon UAG is cleaved at a fast rate while UAA and UGA are cleaved with intermediate and slow rates. In vitro mRNA cleavage can also occur in the ribosomal E site after peptide release from peptidyl-tRNA in the P site as well as on free 30S subunits . In vivo cuts frequently in the first 100 codons, most frequently after the second and third base and rarely near the stop codon . Overexpression of RelE results in the inhibition of bacterial growth and a sharp decrease in colony-forming ability which is neutralized by the labile cognate antitoxin RelB. Overexpression also sharply increases persisters (cells that neither grow nor die in the presence of bactericidal agents and are largely responsible for high levels of biofilm tolerance to antimicrobials) . Plays a role in dormancy when expressed in high-density cells in the absence of antitoxin RelB; amino acid starvation and an unidentified extracellular factor promote dormancy, while expression of antitoxin RelB restores cell culturability . Acts with RelB as a corepressor of relBE transcription, considerably increasing the repression of RelB alone. 2 RelB dimers bind to 2 operator sequences; DNA-binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity .; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MILPDRKQILDRELIRRIADTTISGSGHSDGLSEYASIRKAAFAFVESAVLGDQAYSPIENAELAFIVWILAALDENIITARTIIKARDTVEKQLRLVEHYEDLEEFGSRLGIEISVFGEQIGKDHLYRIGVADFATYASRVTGSKYRLSNQIVREGYVYVDEDVMAKVLREAFVSFMFDTLDQIRKEDAIETIKSVLDDLEKIRESYRKAHNVRMIAGKGDASMFPPCMKEIIKNLESGVNVSHMGRLALASFLHKAGYSEDEIVPYFRNAPDFDENITRYQIKHISGEISGTEYTPPKCETMRSNHLCYMDDDPLCHREWMKHPLTYYEVKRRNRKIR",
    "output": "Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKLTNPGPVPVYTVAGPSTARPLPDWLLRRRKRSAKYDPENLNNFELIQEFEFEEASNCVRVSEDGNWIMSTGTYKPQFHVHNTRELSLSFSRHTNSENVTFLLLSQDYSKSVHLQCDRTLEFHTPMGCHYSIRIPRFGRDLAYLRQSCEVLVPAVGLSSDGSGYGEVFRLDLERGQFLRPWQVDVGEDEPGSGLQGSIHAGAVNVAAVAENTHGLCAFGTSIGTVEFYDPRSKSRVAVLGNQDGEITALDYSRDGLSLALGTSTGQIRIFDLRNPRPLLKKDQGMGLPIKNLIHLTTPTEERKLLSADKRIIKIWDEQSGDLWTSVEPLVDLNFVTHVPDSGMILTANEGKQMHCFFIPNLGLAPRWCHFLDNLVHEMESEKRTETYDNYKFLTKPELKSLSLDHLIGKTNLLRPYMHGFFVHAKLYDQARLITNPYIWEEERAKRIKEKIEKERSSRIRGIKKVKVNQKLVEKIAERQEKKGKPDVAAAMLQDPRFGKLFEDEEFAVDETSREFRALNPSTKIPGAQGDQDGDVKMGDFSSEEESSEGSGSEDEREPRRENKKPEKPKEKPKKVEEPKKHEASKPKDEVVMQIRSSKEQGGKLGDTAFGEREQKDTRASRIRTGEVVGEQVLTFIPESKKKKPQPAPETKPRTDRRSASNNALRKL",
    "output": "May be involved in rRNA-processing and ribosome biosynthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEIEEIKVQTEVNGAPFIIETGYFAKQANGAVIVRQGDTAVLVAAVMSEEPQADIDFLPLTVEYREKYYAYGKIPGGFVKREGKPTDREILVARNIDRPIRPLFPKGFYNDIVITAYTLSADDKYDPDVLGIVGASAALHISDIPFEGPIAGVRVCRVNGEFIVNPTYQQKAQADIEIVVAGSKDAIVMVEGGAKEVPEEDILEAMMFGHQEIKKLIELQEELRLKCGKEKIQVAIDEEEIILKDKLKEFSYEKIKEAFKITDKKQRNKTINAIFEEAFKTLEIPEEKIKKASFIYKDIVSNVMRDNILNEGIRIDGRKPEEIRPIWIKVGVFPRNHGSAIFTRGQTQAFVTVTLGSLSEGQIEESIEAGEVMKRFMLHYNFPPFSTGEAKPPRATSRREIGHGNLAERALEPLIPPEEEFPYAIRVVSDILESNGSTSMATVCGGSLALFDAGVPMKKHVAGIAMGLIKAEDKFVILSDILGDEDHLGDMDFKVAGTRDGVTSIQMDIKVKGLTKEILEKALQQARDGRNYILDLMYQAIPEPRKEVSPYAPTVTTLRVLPDKIPIIIGPAGKNIKKIIEETKVKIDLDPEGLVKIYATSKEAAEKAVSMINELILDVEVGEVYMGKVTRVEDYGAFVELLPGRLSLLHVSQITGERLKSAKEKIKVGDVLKVKVSEIDDQGRIKVSLKDVPENVEPKNKFLFKEE",
    "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPRRREVPKREVLPDPKYGNVDVAKFMNMLMLSGKKSVAERIVYGAFEQIQTKGGKDPLEVFTVALNNVKPVVEVKSRRVGGANYQVPVEVRPSRRMALAMRWLREAAKKRSEKSMALRLAGELSEAAEGRGGAMKKRDEVHRMAEANRAFSHFRF",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MADQIRSATEGGDPTSDPKGFRRALGTFPTGVTIVTAPGVDGPAGVTANSFASVSLDPPLVLWSIGHTSRSHSKFQQSATFAINILADDQVGVSQVFAGGSADKFSLVDWHTGRTGAPLIDNALAYFDCVCEARHEGGDHTIMIGRVVDFGRAEGSPLAFSQGRYGVTLDHPEAAKARDHKSEEYGLDDLPFLSLIAKAHYKEDADLEEQRSAAGCTPVGSKILAGLYGSAPLTADELARRMYLDRREVVDSLNEFVADGHVESCDSGRFALTESGKQRRRRMIEYVSRYQDEQLASISRSDLGVATRVLQAFLAGPGRGSS",
    "output": "Catalyzes the NADH-dependent reduction of the FMN cofactor of the nitrilotriacetate monooxygenase subunit A."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSGELPPNINIKEPRWDQSTFIGRANHFFTVTDPRNILLTNEQLESARKIVHDYRQGIVPPGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKHVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESANAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVGLVGFCLVFATPLCCALFPQKSSMSVTSLEAELQAKIQESHPELRRVYFNKGL",
    "output": "Amino acid transporter importing serine, an essential substrate of the mitochondrial branch of the one-carbon pathway, into mitochondria. Mitochondrial serine is then converted to glycine and formate, which exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors . May also transport other amino acids including alanine and cysteine ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSDDSSDVKPGPKGPEQPAVEQSPENVPAPTGEVHQVGARHGMFGVRGTGDTSGYGGLNQAIVLPGDAQRPYGGWFDEVADGLAAATREAGLEIAAPRVVIHRGEITFHLRREDLLPVAQVLRDDERLRFEFCAGVSGVHYPDETGRELHAVYHLLSMTHNRRIRLEVAVPDADPHIPSIVPVYPTNDWHERETYDMFGIIFDGHPALTRILMPDDWPGHPQRKDYPLGGVPVEYKGGTVPPPDQRRSYN",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVIGAAARVAIGGCRKLISSHTSLLLVSSQCRQMSMDAQSVSEKLRSSGLLRTQGLIGGKWLDSYDNKTIKVNNPATGEIIADVACMGTKETNDAIASSYEAFTSWSRLTAGERSKVLRRWYDLLIAHKEELGQLITLEQGKPLKEAIGEVAYGASFIEYYAEEAKRVYGDIIPPNLSDRRLLVLKQPVGVVGAITPWNFPLAMITRKVGPALASGCTVVVKPSELTPLTALAAAELALQAGVPPGALNVVMGNAPEIGDALLTSPQVRKITFTGSTAVGKKLMAAAAPTVKKVSLELGGNAPSIVFDDADLDVAVKGTLAAKFRNSGQTCVCANRVLVQDGIYDKFAEAFSEAVQKLEVGDGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAKIIIGGKRHSLGMTFYEPTVIRDVSDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTIAGLAAYIFTNSVQRSWRVFEALEYGLVGVNEGLISTEVAPFGGVKQSGLGREGSKYGMDEYLEIKYVCLGDMNRH",
    "output": "Oxidizes specifically succinate semialdehyde. Involved in plant response to environmental stress by preventing the accumulation of reactive oxygen species, probably by regulating proline, gamma-hydroxybutyrate (GHB) and gamma-aminobutyrate (GABA) levels . Required for the maintenance of the shoot apical meristem (SAM) structure and subsequent adaxial-abaxial axis-dependent development of cotyledons and leaves ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSWLLGYVDPTEPSFVAAVLTIVFNPLFWNVVARWEQRTRKLSRAFGSPYLACYSLGSIILLLNILRSHCFTQAMMSQPKMEGLDSHTIYFLGLALLGWGLVFVLSSFYALGFTGTFLGDYFGILKESRVTTFPFSVLDNPMYWGSTANYLGWALMHASPTGLLLTVLVALVYVVALLFEEPFTAEIYRRKATRLHKRS",
    "output": "Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure (Probable) . Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step (Probable) ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSLQTNHRPVLVVDFGAQYAQLIARRVREAGIYSEVIPHTATADDVRAKNAAALVLSGGPSSVYAEGAPSLDAEILDLGLPVFGICYGFQAMTHALGGTVANTGKREYGRTDINVAGGVLHEGLEACHKVWMSHGDAVSEAPEGFVVTASSEGAPVAAFENKERKMAGVQYHPEVLHSPHGQAVLTRFLTEIAGLEQNWTAANIAEELIEKVREQIGEDGRAICGLSGGVDSAVAGALVQRAIGDRLTCVFVDHGLLRAGEREQVEKDFVAATGAKLVTVDERQAFLSKLAGVTEPEAKRKAIGAEFIRSFERAVAGVLEEAPEGSTVDFLVQGTLYPDVVESGGGSGTANIKSHHNVGGLPDDVEFKLVEPLRDLFKDEVRAVGRELGLPEEIVGRQPFPGPGLGIRIIGEVTEDRLETLRHADLIARTELTEAGLDGVIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRLPYEVLEKISTRITNEVPDVNRVVLDVTSKPPGTIEWE",
    "output": "Catalyzes the synthesis of GMP from XMP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MYEYIRGQFQGISKDYVVIELNNIGYRIFTSGNTMSNMPKVGDEVLLYLEQIVREDFIGLYGFTTKEELEMFKLLLSINGVGAKAALSLLSISTVNNLKYAIMMGDEKHITRAPGIGKKTAQRIILELKDKLKPDELTSEEEQLIEGINDNSDYSFNINETLSALMALGYTEKEAQKALEKVDKTLSIENMIKESLKLLMR",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGSIDEVKKESAGETLGRLLKGEIKDEELKKLIKFQFEKRLQWGYKSSHQEQLSFNLDFIKSLKKMEMSGEIETMNKETYELPSEFLEAVFGKTVKQSMCYFKHESATIDEAEEAAHELYCERAQIKDGQTVLDIGCGQGGLVLYIARKYKKCHVTGLTNSKAQVNYLLKQAEKLGLTNVDAILADVTQYESDKTYDRLLMIEAIEHMKNLQLFMKKLSTWMTEESLLFVDHVCHKTFAHFFEAVDEDDWYSGFIFPPGCATILAANSLLYFQDDVSVVDHWVVNGMHMARSVDIWRKALDKNMEAAKEILLPGLGGSHEAVNGVVTHIRTFCMGGYEQFSMNDGDEWMVAQLLFKKK",
    "output": "N-methyltransferase with a strict substrate specificity for (R,S)-tetrahydropalmatine or (R,S)-stylopine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLIFERSRPGRGATAQAPLREATVSGLPERFRRGTRAPLPELSELDVVRHYTRLSQKNFSIDTQFYPLGSCTMKYNPRACNSLAMLPGFLGRHPHAPDTHSQGFLACMFELQEMLRDVTGMKGGVSLTPMAGAQGEFAGVAMIRAYHDARKDTARTEILVPDAAHGTNPATATMCGYTVKEIPTDDSGDVDMEALKAALGPHTAGIMLTNPSTLGVFERRIKEIADLVHQAGGLLYYDGANLNAILGKVRPGDMGFDVIHMNLHKTFSTPHGGGGPGAGAVGVSERLRPFMPIPVVAKEGERYRFMTEKDLPQSIGRLSAFAGNAGVLLRAYVYMRMLGRAGMPRVAEFSTLNANYVMARLREKGFELAFPGRRATHEFIVTLKRLAKDTEVTAMDVAKRLLDFNYHAPTTYFPLLVPECLLIEPTETESKETLDGFVEAMAEILEEARTSPDKVKGAPYTQPNRRFDEVRAARELDVAWRPGAALDEVAEQGRTD",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATLTIDEIVDAISGMTVLEVAELVKKLEEKFGVSAAAMVAASPAAGGAAASPAAEEKTEFDVILQDAGANKLNVIKVVRELTGLGLKEAKDLVDGAPKPIKQGVSKEEAENIKKKLEEAGAKVEVK",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSGNTYGKLFTVTTAGESHGPALVAIVDGCPPGLELSARDLQRDLDRRKPGTSRHTTQRQEADEVEILSGVFEGKTTGTPIGLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLAGLGIQVRGYMSQLGPIEIPFRSWDSVEQNAFFSPDPDKVPELEAYMDQLRRDQDSVGAKITVVAEGVPPGLGEPIFDRLDAELAHALMSINAVKGVEIGAGFASIAQRGTEHRDELTPQGFLSNNAGGILGGISSGQPIVAHLALKPTSSITTPGRSIDTAGEPVDMITKGRHDPCVGIRATPIAEAMMAIVLLDQLLRQRGQNADVRVDTPVLPQL",
    "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGELADPVVIGTITAPHGVRGTVRVRPAGEGRHLREGLSPLVGGRRRRILRARRTPKGFLVDLEGVPDRFRAAELRGEDLLLDRSELDAPEEDEFYVADLVGLEAVDERGGALGEVIETFPTPAHEVLVVRGEGGLLYVPFTREHVPEVDPRAGRAVVRPPEE",
    "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVAAPCARRLARRSHSALLAALTVLLLQTLVVWNFSSLDSGAGERRGGAAVGGGEQPPPAPAPRRERRDLPAEPAAARGGGGGGGGGGGGRGPQARARGGGPGEPRGQQPASRGALPARALDPHPSPLITLETQDGYFSHRPKEKVRTDSNNENSVPKDFENVDNSNFAPRTQKQKHQPELAKKPPSRQKELLKRKLEQQEKGKGHTFPGKGPGEVLPPGDRAAANSSHGKDVSRPPHARKTGGSSPETKYDQPPKCDISGKEAISALSRAKSKHCRQEIGETYCRHKLGLLMPEKVTRFCPLEGKANKNVQWDEDSVEYMPANPVRIAFVLVVHGRASRQLQRMFKAIYHKDHFYYIHVDKRSNYLHRQVLQVSRQYSNVRVTPWRMATIWGGASLLSTYLQSMRDLLEMTDWPWDFFINLSAADYPIRTNDQLVAFLSRYRDMNFLKSHGRDNARFIRKQGLDRLFLECDAHMWRLGDRRIPEGIAVDGGSDWFLLNRRFVEYVTFSTDDLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRITNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFHRFQQTARPTFFARKFEAVVNQEIIGQLDYYLYGNYPAGTPGLRSYWENVYDEPDGIHSLSDVTLTLYHSFARLGLRRAETSLHTDGENSCRYYPMGHPASVHLYFLADRFQGFLIKHHATNLAVSKLETLETWVMPKKVFKIASPPSDFGRLQFSEVGTDWDAKERLFRNFGGLLGPMDEPVGMQKWGKGPNVTVTVIWVDPVNVIAATYDILIESTAEFTHYKPPLNLPLRPGVWTVKILHHWVPVAETKFLVAPLTFSNRQPIKPEEALKLHNGPLRNAYMEQSFQSLNPVLSLPINPAQVEQARRNAASTGTALEGWLDSLVGGMWTAMDICATGPTACPVMQTCSQTAWSSFSPDPKSELGAVKPDGRLR",
    "output": "Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein . Required for normal embryonic and postnatal skeleton development, especially of the long bones . Required for normal maturation of chondrocytes during bone development, and normal onset of ossification (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLILAIYGKGGIGKSTTSANLSAAMALKGAKVLQIGCDPKHDSTFPLTGHLQPTVIDVLDSVNFHLEDVSKEDVIRTGFAGVDTLESGGPPAGSGCGGYVVGETVKLLKEFGLYDKYDVIVFDVLGDVVCGGFSAPLNYADYGLIIACNDFDSIFAANRLCLAISQKSQRHKVKLAGIIANRVDYEYGGGTNLLDQFAEKVGTKVIGRVPYHDLIRRSRLAGKTLFEMEGPGKEECTRPFEEMAEYLLAQPQATVPQPYHDRAIFEAIGGWR",
    "output": "Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRIEVVNVSHIFHRGTPLEKKALENVSLVINEGECLLVAGNTGSGKSTLLQIVAGLIEPTSGDVLYDGERKKGYEIRRNIGIAFQYPEDQFFAERVFDEVAFAVKNFYPDRDPVPLVKKAMEFVGLDFDSFKDRVPFFLSGGEKRRVAIASVIVHEPDILILDEPLVGLDREGKTDLLRIVEKWKTLGKTVILISHDIETVINHVDRVVVLEKGKKVFDGTRMEFLEKYDPRFFTSKMLVMRRLVLKGEDPFSMSDDELLERVCNS",
    "output": "ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (Probable). Expression of the complex plus RibU in E.coli allows riboflavin uptake; uptake does not occur in the absence of RibU or the EcfA1A2T complex."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNLIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVEARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY",
    "output": "Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MWKLLPAAGAAPGEPYRLLAGVEYVVGRKNCGILIENDQSISRNHAVLTVNFPVTSLSQTDEIPTLTIKDNSKYGTFVNEEKMQTGLSCTLKTGDRVTFGVFESKFRVEYEPLVVCSSCLDVSGKTVLNQAILQLGGLTANNWTEECTHLVMSAVKVTIKTICALICGRPIIKPEYFSEFLKAVESKKQPPDIESFYPPIDEPAIGSKSVDLSGRHERKQIFKGKTFVFLNAKQHKKLSSAVAFGGGEARLMAEDDEEEQSFFSAPGTCVVDVGITNTQLIISHSQKKWIHLIMDTLQRNGLRPIPEAEIGLAVIFMTTENYCNPQGQPCTELKTTTPGPSLSQVLSANGKIIPSAPVNMTTYVADTESEPADTCMPLSERPEEVKIPGLEQSSRKLSQETFNIKEAPKPSSKANNVASDTLVRGKTPSYQLSPMKFPVANKNKDWTSQQQQNSIKNYFQPCTRKRERDEDNPELSSCKSSRMELSCSLLEQTQPAGPSLWKSKEHQSQNATLDREADTSSVGGMDIELNRKSPDRKPLPTETLRPRKRKDVDLATEEEVLEELLRSTKPELAVQVKVEKQEADDTIRKKPRMDAERNRPLNGGSEPESNSALQEDEREKKDELQTESWSTKHEIANSDGLQDSSEELPRKLLLTEFRSLVVSNHNSTSRNLCVNECGPLKNFKKFKKATFPGAGKLPHIIGGSDLVGHHARKNTELEEWLKQEMEVQKQQAKEESLADDLFRYNPNVKRR",
    "output": "Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTDYTPQQIVARGARADAEAAADAIDNHPGLEGATYSILEEDEDKGLWRIDAFPTTDEEDAGLLEVLAGYPLKVVRETLADADWLAMALSGLPPVRAGRFFVYGMHDRGRLPASTVNLRIEAGAAFGTGHHGTTVGCLMAYDKLIKARKFKKVLDVGAGTGLLAIAAARTGSRIAVGTDIDRPSVRISKENAKVNRANAKFVHASGLGHRLVTDNAPYDLVFANILARPLISLAQDIKTALVPGGTVILSGLLRTQERMVKAAYVSRGFKVVNRIHRDAWAALVLQRP",
    "output": "Methylates ribosomal protein L11."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLSTVNNNIVIALDAMGGDFAPLSVIHGAGFFLDNLVDPGIKVFFHIYGDKEEVSPLLLKYKKVSNNSEFTHCSDNVLANDKPSFALRHRKDSSMKAAIVAVKEGKAFGVVSSGNTGALMAISRFVLGTLPNIYRPAIASICPTKTKSFALLDLGANVDCNADSLFQFALMGSIFAKIALKIDNPEVALLNIGTEEVKGNDSVRGAFELLKNAPGINFKGYIEASEFLEGNIDVIVADGFVGNVMLKTAEATASTFINLIKQEVFNSWIAKMLVGILLKSKLNKALTRFNPKIRSGAMFLGLNGIIIKSHGNSDAISFAHAIKFAVNAISENLNQKIINGVSHIE",
    "output": "Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDFSIKGCDWSKGTANGFLTGKSDCIVLGVFEAQTLSGAALDIDEATKGLVSRVIKAGDIDGKLGKTLFLHEVSGIGASRVLLVGLGRQDAFSQKAYGDAAKAAWRALLGTKVVQVTFTLAQLPVPERASDWGVRAAILALRNETYKFTQMKSKPDAGAPALKRVVFSVDPADDKAAKVAAKQAVALANGMDLTRDLGNLPGNVCTPTYLANTAKKIAKDWGLKVDVLGLKQIQALKMGSFLSVAKGSVEPPQFIVLQYRGAAAKAAPVVLVGKGITFDSGGISLKPGEGMDEMKYDMCGAGSVLGTMRAVAEMGLKVNVVAIVPTCENMPAGNANKPGDIVTSMKGLTIEVLNTDAEGRLILCDALTYAERFKPAAVIDVATLTGACIIALGHHNTGLFSKDDALAGELLDASREAGDPAWRLPLDDEYQDQLKSNFADLANIGGRPAGSVTAACFLSRFAENYPWAHLDIAGTAWKSGAAKGATGRPVPLLAQFLIDRAGA",
    "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKEKEKIIVAMSGGVDSAVAAGLLMEAGYDVIGVNLRTWEYEAPACDTTKKSCCSPEDIRDARDVGLSLNIPFYVIKMEKVFGERVIDRFISDYKDGRTPNPCVECNTFVKFGALFEQAKKLGIDKIATGHYARVIEVDGRYAIRNAVDMKKNQTYYLYGLSQDNIKNTVFPLGEMDKSEVREIAKRMGLPVAEKPESQEICFIPENDYRSFLKKKGMEFTPGFFKLASGQIIGKHQGKEGFTIGQRKGLGIAWKNPLYVLSIEDDGTVVLGEEEETVSESFVLEEITYQALAPLALGQSMEMKVQIRYRSAPVHCKVTSLGETWKVNFLEDVKSVTPGQSATFYPTNGDYLFAGGIIQKGSITRKIKSNVEVQRESVPI",
    "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLSKELLAALNEQMNQEYFAAHAYMAMAAYCDKESYDGFANFYIEQAKEERFHGKKIYDYINDRGEHAIFDTIKAPKVEFSSILETFKDSLAQERDVTQRFYNLSELARNDKDYATISFLNWFLDEQVEEESTFETHIDYLTRIGDDCNTLYLYEKELAARSFNEQ",
    "output": "Iron-storage protein."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDVTAEAKQIMVQALGKMYSSRSQRGGLRLHRSLLLTLVMKSARDIYHSARLMSEKSGQSVTEECTSHTQEPMDTSSSTATPLRETSGQSSEDGQRSGLEGHPHPLNPAADKENCGPSRPDRHSRKRRSKTATDSDFIPCKKAKLECAEVRGVLQNSSANCGRALDSLSLVPMPRTIVTF",
    "output": "DNA-binding protein that seems to act as a transcription factor (By similarity). Mediates with FIBPB FGF-signaling in Kupffer's vesicle ciliogenesis and in the establishment of laterality in the embryo ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNRDTSPDLHYLSGFGNEFASEALPGALPVGQNSPQKAPYGLYAELLSGTAFTMARSELRRTWLYRIRPSALHPRFERLARQPLGGPLGGINPNRLRWSPQPIPAEPTDFIEGWLPMAANAAAEKPAGVSIYIYCANRSMERVFFNADGELLLVPEQGRLRIATELGVMEVEPLEIAVIPRGMKFRVELLDGQARGYIAENHGAPLRLPDLGPIGSNGLANPRDFLTPVAHYEEAEGPVQLVQKFLGEHWACELQHSPLDVVAWHGSNVPYKYDLRRFNTIGTVSFDHPDPSIFTVLTSPTSVHGMANMDFVIFPPRWMVAENTFRPPWFHRNLMNEFMGLINGAYDAKAEGFLPGGASLHGVMSAHGPDAETCEKAIAADLAPHKIDNTMAFMFETSQVLRPSLQALECPQLQADYDSCWATLPSTFNPNRR",
    "output": "Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSTSTTFQIHYFASASTYTGKQTERLPAPLPLPQLFDTLESMYPGIKEKVLTSCGVSLGDEYVDVEADIQVMIHPGDEVAVIPPVSSG",
    "output": "Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by uba4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSYSGERDNLAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGISIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMAHHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN",
    "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGVLKRRVSSSRGLGGVLREQRAKLYIIKRCVVMLLCWQD",
    "output": "Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLGDSVNALTLEHYPGMTEKALAEIVDEARNRWPLGRVTVIHRIGELWPGDEIVFVGVTSAHRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW",
    "output": "Converts molybdopterin precursor Z to molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATNIRKTHPLLKIINHALVDLPAPSNISAWWNFGSLLVLCLAVQILTGLFLAMHYTADISLAFSSVIHICRDVNYGWLIRNIHANGASLFFICIYLHIARGLYYGSYLLKETWNIGVILLFLLMATAFVGYVLPWGQMSFWGATVITNLLSAFPYIGDTLVQWIWGGFSIDNATLTRFFAFHFLLPFLIIALTMLHFLFLHETGSNNPLGLNSDMDKIPFHPYFTYKDILGFFTMTLFLGALVLFLPNLLGDAENFIPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILMLLLVPFLHTSKQRTNTFRPLTQLLFWTLVANTIILTWIGGQPVEQPFIFIGQIASITYFSLFLIITPFISWCENKILSLN",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSGFGGRGVDEKGFLRWLLGELGVEEDDVAYVDGLVVKVDGAAASTSRLPFQTWADFGWRNVAAAYSDVRVKFAEARLLLASVTAPDLGTAAEVVQGVREASQFFSLAYVGGDLNEGRDVVVDVVLVGWARARVGRAPRPGDVLVTIPQFGYTSLAYRFWQMGGAVVERGVEALKRPKPLWPLPPAECVTAAMDSSDGLGDVLWSMARGVDIVVKELPAPREVLEFAAERGLDVGEIVFNGGEEFLPVFAVRRDCPVESPYVSFAEVVPGEGRVWWRGEELKWRGWAYFRGWG",
    "output": "Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVFEKVKDIIADQLGIDATEIKMESSFIDDLGADSLDIVELIMALEEEFDIEMPDEEAEKVSSVGDVVNYIKAHTEE",
    "output": "Carrier of the growing fatty acid chain in fatty acid biosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKNSHIYILYGSETGTAEGLAESLFRSLTRMGYDVLVNSMDDFNLENLLRPLQCVFICSTTGQGEMPLNMRKFWRFLLRKKLPNTFLNDMQYAVFGCGDTSYTRFNWASKKLDSRLRQLGAQSFSSRGEGDEQHPDGVEGVFAYWCNHLYSQLAAIKTPSRPAFGEFDLLPPSFQIIIDESLGCKVKGFEDNNIVRHSRGKIEATLVHNKRISNIKHWQDVRHLAFKIPNFERWKPGDVAVLYPWNDDMSVNSFIECMGWESIKYSPLIISSNVAERKLPWFPNILNVFNLVKYVLSIHSVPSRTFFEMASHFSNNKMHKERLQEFSSYKNIDDYYDYTTRPRRTVLETLQEFKSVQIPIEYALDAFPVIRGRQYSIANRCDNSTGILELAVALVKYQTILKSPRQGICSRWICDLHENTSFNIDILPGFLNLSYQSNKPLIMVGPGTGVAPLRALIQERIYNGLKENLLFFGCRNKSMDFLFEKDWEKYTEEGTLKLFCAFSRDQEKKKYVQHSIQENGELVYNLLNEKDGMFFVSGSSGKMPSSVKDAIAGIVSKYSGCSISDGYSFVTSLEKKNRYYQETW",
    "output": "NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of dre2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAEIKAAQVMQLRKKSGAGIMDAKKALVASDGDMDKAMDYLREKGIAKAAKKSDRVAAEGLADIAVNGNTAAIVELNSETDFVAASEPFKDLLKKVTKLISENKPANVEEALEIKTENGTLNDDIISTTQKTGEKVSLRRFTVVEKDDGDSFGAYLHQGGQIAALVVLEGADDATAKDVAMHVAAINPEFMTRDDVSQERLDHERAIFKEETLNEGKPEKIVDKIVEGRLNKFLSQICLADQDFVKDSDQTVEQYVSSKNGKLKSFIRYEVGEGIEKKQDDFAQEVKDQMN",
    "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEGAELIIQEINREAEQKIQYILSEAQKEAEKIREEARKRAQARAEWILRKAQTQAEIEKQRIIANAKLEIRKKRLEVQEALIQEVITALRERLAELPEEEYFPMLVDLTGKAVEELGSGSVVVKSNERTLKLLEGRLDEFKKALTEKLGRDVEVTLGEPITTIGGILVETPDRTVRVDNTFESRIERFEGELRAAIAKALFG",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNRLAVEIPGLSLKNPIMPASGCFGFGQEYSKYYDLNELGAIMAKAVTPEPRLGNPTPRVAETASGMLNAIGLQNPGLEHVLAHELPFLEQFETPIIANVAGATEDDYVQVCARIGESKAVKAIELNISCPNVKHGGIAFGTDPDVAHRLTKAVKNVATVPVYVKLSPNVADIVSIAQAIEAAGADGLTMINTLLGMRIDLKTRKPIIANGTGGLSGPAIKPVAIRMIHQVREVSNIPIIGMGGVQTVDDVLEFLIAGADAVAVGTMNFTDPFICPKLISELPKRMDELGISSLQELKKERTNQ",
    "output": "Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRLDILLFTLSSSTSLALSYSLPMDPAHSSVHTLSAADRHIGERVTRQRHLREEPANEARNYSDLAVEIKRLVEELDSRVLEQADISLLDRHYAGDYKAFRSDLMTYGYQTRFAEQYKLFKKLGIDFKHNY",
    "output": "Secreted effector that suppresses callose deposition, a hallmark of pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) and renders host plants more susceptible to bacterial infection . Reduces host plant responsiveness to salicylic acid (SA) in haustoriated cells into which host-translocated effectors are delivered ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRDYSKEIKSWAAELGFDFCGISAADFLEEEAPRLERWLNRNYHGKMAYMANHFDKRLDPRKLVDGAKSVVSLLLNYYPEEPLDASPYKISKYAYGKDYHYVIKDKLKLLFERIQKEIGEVGGRIFVDSAPVMDKIWAKKAGLGWVGKNSNLINRKMGSFFFIAELILDLPLQADGPIRDYCGTCTACIDACPTDAITPYEVDGSKCISYLTIELKDQIPNEFKGKMENWIFGCDICQDVCPWNSFARPHSTEEFYPNENLKTFQDWDEITSEIFSHLFKKSAVERTKLEGLKRNIAFVKEV",
    "output": "Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "NLFQFGEMIFEKTGKEAVHSYAIYGCYCGWGGQGRAMDATDRCCFVHDCCYGRVNGCNPKMATYSTSFQNGDIVCGDNDLCLRAVCECDRAAAICLGQNVNTYNKNYEHYSISHCMEESEQC",
    "output": "Heterodimer: presynaptic neurotoxin.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSVVNRRIAVYPGTFDPITNGHIDLVSRAAPLFESIVVGVAQSPSKGPSLPLQQRVALAREALCQHENVQVIGFDTLLAHFVRHVGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQHSFISSSLVREIARLGGDVSGFAPAAVVAALRQNL",
    "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNPITYELIKTDKQTGARLGRVHTPHGSFDTPTFMPVGTLATVKTMSPEDLQSMQANIILSNTYHLWLRPGEDIIREAGGLHKFMNWDGAILTDSGGFQVFSLSDMREIKEEGVHFRNHLNGEKLFLSPEKAMDIQNALGSDIMMAFDECPPYPAEYDYMKASVERTSRWAERCLQAHNRPHDQGLFGIVQGGEYEALRKQSAEDLVSLDFPGYAIGGLSVGEPKHVMNKVLEFTTPFLPSNKPRYLMGVGSPDALIDGAIRGVDMFDCVLPTRIARNGTCMTSNGRLVVRNAKYARDFNPIDEHCSCHVCKNYSRAYIRHLIKCNETFGFRLTTYHNLHFLLKLMEQVRTAIKEDRLGDFKESFFEQYGLNKANPKNF",
    "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASVIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP",
    "output": "Probably mediates the hydrolysis of some nucleoside diphosphate derivatives."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "PTMPVDSRIIEDAIRNHSESASPSASSGSPNNMSPTGWSQPKTPVPAQRERAPGTNTQEKNKIRPRGQRDSSYYWEIEASEVLLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHGGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIALLQHSLPKINRSASEPSLHRASHTEDINSCTLTSTRLPVF",
    "output": "By itself the v-Mil oncogene has only weak transforming capacity but it abolishes the growth factor requirements of avian macrophages transformed by other oncogenes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARKSLIQREKKRQVLEQKYHSIRQSLEREISEVSSLDDKWEIHRKLQSSPRNSTPTRLHRRCFLTGRSRANYRDFGLSGHVLREMTHACLLPGMKKSSW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "PMGMTQPLSHSNQMPSPNAMGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGNFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFAVLG",
    "output": "Involved in signal transduction through the Wnt pathway. Promotes beta-catenin's transcriptional activity (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQQGWLSNWLVKHDVVHRSLGFDHRGVETLQIKAGDWDSIAVILYVYGYNYLRSQCAYDVAPGGSLASVYHLTRIQYGIDNPEEVCIKVFAQKDNPRIPSVFWVWRSADFQERESYDMVGISYDNHPRLKRILMPESWIGWPLRKDYITPNFYEIQDAH",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSMSIMDFINDLKKKNITLYHNKGKIKIIGPQELLTADLKQQIKRYKEDIIAALEAGETDIERSFPKAAPSKSGTYPLSREQKRMFILNQLDDSKTAYNMPLAVKINGEVQISRLEQAWKALIKRHESLRTSFVMLDGEPVQKIEQEAEFRLEYSELGDQSIQEKISRFIKPFELEKAPLLRAEIVKVDEAEHMMMVDMHHIISDGVSIGILMKEFADCCEGKELSPLAVQYKDYSEWQRDIEQQSRLKKQEAYWLNTFRGDIPVLNMPLDFPRPKIRSFQGNRTVVELDQDTTKKLKTIAAKNGVTMYMLLLAGYTILLSKYTGQEDIIVGSPIAGRPHADLNGTIGMFVGTLALRNRPKGNMTFSEYVQTVKNNTLKAYENQDYQFDALIEHLGLTHDMSRNPLFDTMFDLQHADDFASEAGGGHFETYDIPFHVAKFDVSLTAFLHGDNLKFDFQYCTDLYKKETVERMAGHFLNVLKDAAHHPELALSEIRMMSEEEKDIILHTFNHEKTDGPKNKTLSRLFEERAEKTPDHTAVIFEDQQLTYRELNEKANQLAWLLREKGVKPDTIVAIMTDRSLEMIIGIIGILKAGGAYLPIDPDYPEDRVKYMLEDSGADMVVIQEPFKSKIDGRQLITAEDTRSFSKENLPNVNKASDLAYVIYTSGSSGRPKGVMTTHRNVVHYVDAFTKRIPLSEHDTVLQVVSFSFDAFSEEVYPILACSGRLVISRKVSDLNIDELVKTIGKYRVTLVSCSPLLLNEIDKNQHLTFHPQMKFISGGDVLKFEYVENIIKGADVYNSYGPTEATVCATYYQLSSADRKKTSIPIGKPLSNYKVYIADQYGRPQPVGVPGELLIGGEGVARGYLNHETLTKAAFVVDESGERVYRTGDLARWLSDGNIEFLGRIDSQVKIRGYRIELEEIEHRLLMNDNINEAIVVAKEDQENSKYLCAYIAFNNKNADIEQVQERLAKDLPEYMIPSCFIKLDQIPRTINGKADLKALPEPDRRAFAQARYEAPRNQTEALLLSIWQDILPAEQIGINDHFFDIGGHSLKAFSMAAKIQSALKVEVTLKEIFNHSTIQDLAAYIAQKQKQVQSDIQKAEKKEYYPLSSAQKRLYILNQIEEGQTAYNMPFAMKIKGELQTDKAEKAFRTLIKRHESSRTSFVTINGEPVQNINEEVTFEMKYRELDNCSLRERMNQFIRPFELEKAPLLRAELVRVNAAEHILLLDMHHIISDGVSIGILMKEWAALYEEKELAPLKIQYKDYSEWQRDPWQKDRLKKQEESWLSVFQNDIPVLNMPTDFPRPQMQSYEGDRIAFAIERELTDKLKKTAKENGVTMYMLLLAGYTILLSKYTGQEDIIVGSPIAGRTREELEQTVGMFVGTLAMRNHPKGGRTFIEYLQDVKENTFNAYENQDYPFDELVDKLDLERDISRNALFDTMFDMQALDDAEPDIEGLHVEPVDLEFQISKFDLSLTAAESAGVITFHLEFCTRLYKKETAETLAQHFVNILRDISDHPQKTLNDISMLSEEERHTVLYQFNDTNTEHPSGIFSELFEEQAEKSPNHPAAVFKDQMLTYRELNEKANQLARTLRQKGVQRESVVGIMAERSLEMLTGILAVLKAGGAYMPIDPGLPKERIQYLITDSGADLLLTQHQLIGSISFAGEIIQIDQADAYDTDGSNLEHLNSPGDLAYVIYTSGTTGNPKGVMVEHRNIIHAHYTWRKHYELASFSVNLLQLASMSFDVFAGDLCRSLLNGGTMYIVPDDVKLEMNLLYDMINKYGIHMLESTPSLIIPLMKYIDHHKLDFSSMKLLIMGSDTCTIKDYKWLVERFGQRMRIINSYGVTEASVDSGYYEEALDRIPEIANTPIGKPLDNTAFYILDPSLNPQPVGVYGELYIGGEGIARGYLNKPELTKERFVPNRFAAGGNMYKTGDLARWLPDGNVEFLGRIDHQVKIRGFRIETGEIETKLLENQNISEAVVIDREDKKGHKYLCAYIVARAKTNTNELREYLSDHLPDYMLPSYFIQINKMPLTPNGKIDRKALPEPAGDVIAASGYEAPRNETEEKLAAVWQEVLDRDKIGINDNFFEIGGDSIKALQIVSKLSRADLKLQVKDLFTNPFIRHLSKYVKKETKARTSEIVQGQVPLTPVQRSFFEANQREQNHYNQAFMLYRENGFAERIVEKVFRKLTEHHDALRMVYWEKNGDIIQHNRGLEDSVFDLYVYDLKTEKNLEKTVYQIATNIQKDISISEGKMIKLCVFKTTEGDHLLIAIHHLLVDGVSWRILFEDFEAAYGQALQGKPIELGYKTDSYKTFSEKLAEYANSKKLLKEQEYWREISKGKMAFLPKHRQAAHDNYENSRTLRISLSQTETEQLLKEAHKAYNTQINDLLLTALLIASRQLTGENRLKILMEGHGRDDILQDVDITRTVGWFTAMYPVFIDLEDEADLSVMIKIVKETLRKIPNNGIGYGILKYLRKDEGLLKDEKPPILFNYLGELDHDLTTEQFSSSKLSAGQSIGEKSARDASVEIDSVVAGRQLMISTTFNEYEYSPDTISELNQAFKESLQMVISHCTGKHETEKTSSDYGYDKLSLEDLEELLNEYESVDS",
    "output": "Activates two amino acids and incorporate a D-ornithine from its second active site into bacitracin."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALKIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYKYNLTDINAAIALTQLVKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPDMTTADADHVITALQQLAGQ",
    "output": "Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSGDGSCSYSAEEGIRELLQSAKAKFRESVDVAIKLSVADSKSGESIRGAVVLPKGLGREVRVAVFAKGEHAKQASSAGADVVGDEELIEEIKKGRRLDVDWCIATPDFMPQISAIAKILGPRGLMPNPKFGTVTLELAEMVGIIKSGQVKFKSDRYGIVHVKIGDIGFTPEDLLENFNAVVAAVQGLRPTTIKGSYVRGVFVNSTMGRSFRIAGTG",
    "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKKIECIIMDWAGTAVDYGCFAPVAAFIKAFAGKGLTIDVEQTRKPMGLPKIQHIRELLTMPEVNEQFINRYRRAWTEEDVVELNHLFEKYLFASLKEYTDPIPGVIPTLEKLRAEGLKIGSTTGYTREMMDVVLPEAQAKGYRVDYCATPNLLPAGRPAPYMIFENLTKLAVPDPDTVVKVGDTIADIQEGVHAKVWSVGVVLGSNEMALTEEETHALPAAELENRIAEVKQRMLAAGASYVIRSIEELPALIQLINSKLNH",
    "output": "Involved in phosphonate degradation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPEVKRLSDGIFEVIKDKKQLATKNLDPGKTVYGEKLIAVEGVEYRTWDPRRSKLGAMVLKKFNIPLTKNSKVLYLGAASGTTVSHVSDIVSEGAVYAVEFAPRSMRDLIGLASRRKNIHPILADAGKPDSYSHLVEPVDLIFQDVAQPNQAEIAARNAVRFLKREGYLLLSIKARSIDTVAKPKEVFKAEVKKLEQAFEPRFEILNAKDLMPYHEDHLGVLAKLK",
    "output": "Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPIATINPATGETVKTFTAATDDEVDAAIARAHRRFADYRQTSFAQRARWANATADLLEAEADQAAAMMTLEMGKTLAAAKAEALKCAKGFRYYAENAEALLADEPADAAKVGASAAYGRYQPLGVILAVMPWNFPLWQAVRFAAPALMAGNVGLLKHASNVPQCALYLADVIARGGFPDGCFQTLLVSSGAVEAILRDPRVAAATLTGSEPAGQSVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVSTAVTGRVQNNGQSCIAAKRFIVHADIYDDFVDKFVARMAALRVGDPTDPDTDVGPLATEQGRNEVAKQVEDAAAAGAVIRCGGKRLDRPGWFYPPTVITDISKDMALYTEEVFGPVASVFRAANIDEAVEIANATTFGLGSNAWTRDETEQRRFIDDIVAGQVFINGMTVSYPELPFGGVKRSGYGRELSAHGIREFCNIKTVWIA",
    "output": "Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate. It is believed to be the main source of succinate semialdehyde dehydrogenase activity in Mycobacterium. NAD(+) can substitute for NADP(+), but enzymatic activity is three times reduced."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIQGTTSDAGKSTLVAGLCRLARRTGARVAPFKPQNMALNSAVTANGGEIGRAQALQALAAGIEAHTDLNPVLLKPTGDRGAQVIIHGKARANLDARAYHDYKPTAMRAVLESYGRLRGAYDAVIVEGAGSPAEINLREGDIANMGFAEAVDCPVVLVADIDRGGVFAHLVGTLACLSDSERARVRGFVINRFRGDPALLEPGLRWLEARTGKPVLGVLPYLHGLTLDAEDMLPASARTSAARRDAGVLRIVVPALPRISNHTDFDALRAHPRVDFTYWRRGPVPDADLLILPGSKNVLADLAWLRDAGWDALIKRHLRYGGKVIGICGGMQMLGRTLADPHGVEGAAGATSAGLGLLDYATTLTPEKTLVNAAGRLAFGGDARVAGYEIHMGRTEGPALASPALMLAGRGGERPDGALSADGQILATYLHGLFDTPHACAALLEWAGLDGAEALDYPALREASLERLADTFAEHLDLDRVFAAFA",
    "output": "Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSKRDYYEVLGVARTANDEELKKAYRRCAMKFHPDRNPGDAAAEASFKECKEAYEVLSDGNKRRMYDSHGHAAFEHGMGGGGGPGGPDMNDIFGDIFGNIFGGAGGGGPRQARRGADIGYVMELDLEEAVRGVERRIEIPTLAECGDCDGSGSEDGKVETCNVCHGRGQVRIQRGIFAMQQACHNCGGRGQIIAKPCKTCHGNGRVEEDKVLSVKVPAGVDTGDRIRLSGEGEAGPAGTPPGDLYVEVRVREHAIFQRDGDDLHCEVPIRISQAALGDTVRVATLGGEAEIRIPAETQTGKLFRLRGKGVRSVRSRSEGDLYCRVVVETPVNLTNDQRKLLEQFEATFNGEDARKHSPKSATFIDGVKGFWDRMTS",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTIRYPNGKRYNQASQPHKTPIKKHTYSNRGMSLEEELNETNEYYLTHNIACVHKKPTPLQIVKVDYPARSAAVVKEAYFKQPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQIEHMKQVIAHNGIAFVIIKFTLFDELYLLDAKHIITFWNRQNTGGRKSITKEEIVEHGSLLSCGYHPRIDYIRVLDTVYFS",
    "output": "Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVPPPSNPQQVQQFLSSALSQRGPSSVPYEESNKWLIRQHLLNLISSYPSLEPKTASFMHNDGRSVNLLQADGTIPMPFHGVTYNIPVIIWLLESYPRHPPCVYVNPTADMIIKRPHAHVTPSGLVSLPYLQNWVYPSSNLVDLVSDLSAAFARDPPLYSRRRPQPPPPSPPTVYDSSLSRPPSADQSLPRPFPPSPYGGGVSRVQVQHVHHQQQSDDAAEVFKRNAINKMVEMVHSDLVSMRRAREAEAEELLSLQAGLKRREDELNIGLKEMVEEKETLEQQLQIISMNTDILDSWVRENQGKTKNLVDLDVDNAFECGDTLSKQMLECTALDLAIEDAIYSLDKSFQDGVVPFDQYLRNVRLLSREQFFHRATGSKVRAAQMEVQVAAIAGRLHS",
    "output": "Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process . Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) . May control nuclear division through the microtubule cytoskeleton ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNQTLLSDFGTPVERVERAIDALRNGRGVMVLDDESRENEGDMVFAAEAMTVEQMALTIRHGSGIVCLCITDERRQQLDLPMMVANNSSQFQTAFTVTIEAAKGVTTGVSAADRLTTIRAAIADNAKPTDLNRPGHVFPLRGQPGGVLSRRGHTEASIDLATLAGYKPAGVLCELTNDDGSMAHAPEVIEFAKLHDMPVVTIDDLAEYRQSQEKKAS",
    "output": "Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAENVTSAKATAFQVRIAPRKARLVLDTVRGKSVNEAYAILKFLPNTGTEPVYKVLNSAVANAENNFALDRADLVIKEAYANEGPTMKRFRPRAKGTASKINKRTSHITIVVSENDKKGA",
    "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKPEFHIFICAQNRPAGHPRGSCGAKGAEGVYNAFAQVLIQKNLTNRIALTTTGCLGPCQAGANVLIYPGAVMYSWVEPADAAIIVEQHLLGGEPYADKLTPAEIW",
    "output": "Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Might be involved in nitrogen fixation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIQPQTYLNVADNSGARKLMCIRVLGGGNRRYGFIGDKIIAVVKDATPNMAVKKSDVVEAVIVRTRKAVSRDSGMSIRFDDNAAVIINKDGNPRGTRVFGPVARELRDKNFTKIVSLAPEVL",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLRILLSNDDGITAPGIQTLAAALREFAQVQIVAPDRNRSGSSNALTLDSALRITTLSNGDIAVQQGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGQQHYATAAAVTCRILRALQHKPLRTGKILNINIPDLPLSEIKGIRVTRCGSRHPAEQVFCQQDPRGQDLYWIGPPGEKFDVAEDTDFAAVEQGYVSITPLQVDLTAYGAQDVVENWLASMAD",
    "output": "Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPFRVEVLNETSGGARLTPERATELCRRAFVERGLDPERMGELSVALVEPEVIHDLNLKFRNKDAPTDVLSFEVDGPYGEMVGEIVICPGCAEMDLEELVVHGALHLSGMDHGENFEASEMARVQKRVMEAVRGR",
    "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MANTASAEKRNRQAQKRRARNVQVRTGVKSAVKKLREAIAKGDPAATQVALKSAEKTIGKAASKGVLHKNAASRKISRLAKAAAKPAAAAK",
    "output": "Binds directly to 16S ribosomal RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDSQCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEEVNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH",
    "output": "Receptor for ATP that acts as a ligand-gated cation channel . Plays a role in sensory perception. Required for normal perception of pain. Required for normal taste perception (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEPRAVAEAVETGEEDVIMEALRSYNQEHSQSFTFDDAQQEDRKRLAELLVSVLEQGLPPSHRVIWLQSVRILSRDRNCLDPFTSRQSLQALACYADISVSEGSVPESADMDVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLLTALRTDVRQQLFQELKGVRLLTDTLELTLGVTPEGNPPPTLLPSQETERAMEILKVLFNITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTEEFHGHAVNLLGNLPLKCLDVLLTLEPHGDSTEFMGVNMDVIRALLIFLEKRLHKTHRLKESVAPVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQDAMCETMEQQLSSDPDSDPD",
    "output": "Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDMSERIIVTYQVAAAPAEIAARAEALAIEQSVECPLAAVTEQQIRDEIVGRVEAIAPIGETRFSVRVSLASATAPAEPGQLLNMLFGNSSIQPDVTLADVELPPAYPAAFGGPKLGISGLRAKLGAPRRALTGSALKPQGLAPEALAGLAHRLALGGVDLIKDDHGIADQAFSPFAARVPAVARAMREACAVRGAAMLYAPHVSGSLDDMRRQLDIVRREGLSVVMLMPMIVGLANFHLIAKEAEGLIVLAHPSLAGAQRIAPDLLLGKLFRLLGADATIFPHYGGRFAYTPETCRALADAARRDWHDLKPCLPVPAGGIAIDRIKELLAFYGTDVMLLIGGSLLAAGEQLTEHAARFTAEVASHGQ",
    "output": "Unknown. Probably does not have RuBisCO activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKWSEISIHTKEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAEGVLIKAYFPQTDSLHETIAGVKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHPVQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHPTTTMCIRALEKTVQQGDTIIDVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDIVSVGQNSLLEGIEGPVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLRMEDWVAIIARNA",
    "output": "Methylates ribosomal protein L11."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKVLLRLPALLASLTLLQMAASTRNATRTATIRETVDEVKVQVNKAFLDSRDRLKTDMSNLAPTVRHLSGYLKQAKGRTRTAIRVGQVWEQSLKRLRRMVPLTNVTGQGLDLTSLSWEVGCGHPAPTVTCNISNPYRTITGDCNNRKNPELGSANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPQPRDVSNQVLDYLNEEEILDQNRSLLFMQWGQIVDHDLDFAPETEMGSDNYSKAQCDELCIQGDNCFPIMFPKGDPKLKTQGKCLPFFRAGFVCPTSPYQSLAREQINALTSFMDASMVYGSEPSLANRLRNLSSPLGLMAVNEEVSDHGRPLLPFVNVKPSPCEVINRTAGVPCFLAGDSRASEQILLATSHTLFLREHNRLARELSRLNPQWDGEKLYQEARRIMGALIQIITFRDYLPILLGDELQKWIPPYQGYKETVDPRISNVFTFAFRFGHLEVPSTVSRLDENYQPWGSEPELPLHKLFFNTWRVVKDGGIDPLVRGLLAKKAKLAHQDKMMTGELRNMLFQPNHTVHGFDLAAINIQRCRDHGQPGYNSWRAFCGLSQPKTLEELSAVLRNEVLAKKLMDLYGTPDNIDIWLGAIAEPLVRRGRVGPLLTCLLGQQFQRIRDGDRFWWENPGVFTEKQRDSLQKMSFSRLVCDNTGINKVPLNPFQPNSYPHSFVDCSAIEKLDLTPWASVKK",
    "output": "Heme-containing oxidoreductase which catalyzes the conversion of thiocyanate (SCN(-)) into antimicrobial agent hypothiocyanous acid (OSCN(-)) in the presence of hydrogen peroxide (H2O2). Also involved in the conversion of iodide (I(-)) into hypoiodite (IO(-)) in the presence of H2O2 (By similarity). Responsible for the inactivation of a wide range of micro-organisms and hence, important component of defense mechanism. May be implicated in airway host defense against infection (By similarity). May contribute to maintaining an appropriate H2O2 cellular level, therefore protecting cells from H2O2-caused injuries and inflammation (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKTSQKVRNHRPAKFSSREYTRCERCGRPHSVYRKFGLCRICLKELGHKGQIPGLKKASW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLAKRIIPCLDTIGKKVVKGTSFINVRVVGDAKELARRYEKEGADEIVLLDITASEEGRSTFVDVVTDVASELFVPLTVGGGIKNIEDVRRLLKAGADKVSINTSAVENPDLINQIASEFGSQCLVVAIDVKRRGKKSWEVYIKGGKVPTGIDFKDWVIEVEKRGAGEILLTSIDADGHLSGYDYELLEYALSYSNLPLIASGGAGSLEDLYKALKIGVDAVLAASIFHFGTYSIPEVKRYLREKGIWVRLD",
    "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFMNLLSQVSNAIFPQVEAAQKMSNRAVAVLRGDVVSGTIWITQNSESDPAVIEGEIKGLTPGLHGFHVHQYGDSTNGCLSAGPHFNPFGKTHGGPNSETRHVGDLGNVEAGADGVAKVHITDKLITLYGANTVIGRSMVVHAGQDDLGQGVGDKAEESAKTGNAGARAACGVIALAAPQ",
    "output": "Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Required for normal brood size. May be involved in regulating mpk-1 phosphorylation downstream of phosphatase ptp-2 during oocyte maturation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSPVPLKNAERAHSGVRTVSVLGATGSIGDSTMDLIRAEPERYRVEALTGNANVAGLAKLAKEFNARFVAVADPARLGELRAALAGTDVACGAGESAVIEAAARPADWVMAAISGAAGLKPALAAVDRGTTVALANKECLVCAGDFFMSRATAAGAQILPADSEHNALFQALASGNRHELTRVIITASGGPFRTWAAADIEQATLAQALKHPNWSMGQKITIDSASMMNKGLEVIEASYLFALSPDEIDVLVHPQSIVHGLVEFADRSVVAQLGAPDMRIPIAHCLGFPDRITGRAAKLDLAKIGQLTFEAPDFTRFPGLRLAYDALRTGNGATTVYNAANEVAVAAFIAQKIRFGAIARLVEDTLNSWVRAGNQAPLGSADDAIALDQQARNLAATLLPQIAAKAS",
    "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MYNGKDRAQNSYQPMYQRPMQVQGQQQAQSFVGKKNTIGSVHGKAPMLMANNDVFTIGPYRARKDRMRVSVLEKYEVIGYIAAGTYGKVYKAKRQINSGTNSANGSSLNGTNAKIPQFDSTQPKSSSSMDMQANTNALRRNLLKDEGVTPGRIRTTREDVSPHYNSQKQTLIKKPLTVFYAIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKYRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIPVSENVFEGLTYKYPARRIHTNDNDIMNLGSRTKNNTQASGITAGAAANALGGLGVNRRILAAAAAAAAAVSGNNASDEPSRKKNRR",
    "output": "Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II RPB1 at serines 2 and 5. The SSN3/SRB10 and SSN8/SRB11 kinase-cyclin pair may also positively and negatively regulate numerous transcriptional activators in response to changes in nutritional and physiological conditions. Phosphorylates GCN4, promoting its ubiquitin-mediated degradation, and MSN2, promoting its nuclear exclusion. Phosphorylates STE12, thereby promoting its degradation and inhibition of filamentous growth. Phosphorylates GAL4, and this phosphorylation is required for efficient galactose-inducible transcription. Also phosphorylates BDF1 and the TAF2 subunit of the TFIID complex."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF",
    "output": "Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLSNSVNNNNNNNNINNSNSNNNDSNIHKNVKKLMVASIFGGIMSSLIVTPLDVVKTRLQTQNTGSHINQKHVFKGTLDAFKKIYKNEGPLTFWRGVTPSLLMTIPSATIYFTSYEYLKEYLYQFNDTEAYNIYTVPLVAGTLARIFSASVTSPFELLRTNSQGIVLQNAYKNTVAMAASSSTATIGTIPLSSEQRFNSFKLYRDIVNNVGIKGLWRGLGPTLVRDVPFSAIYWAGYEVLKNKLMKSQIDPNFSRNSKSPFFINFIAGATSGTLAAVLTTPIDVIKTRIQMSAQQTLSPSLTPQQQLDFIKKNNSSIYHLKQILSQEGWKGLTKGLVPRVAKVSPACAIMISTFEYIKQSHIADDN",
    "output": "Mitochondrial transporter required for glutathione import into mitochondria."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSHLTGTRVSTFNESFLNENEHDSNAVLMELDKGLRSTKQGIQCEAVVRFPRLFEKYPFPILINSSFIKLADYFVSGSNLLRFWVLRVCQQSENHLDKILNIDSFVRCIFVVMHSNDPVARALLLRTLGAVSRVIPEKQQVHHAIRRALDSHDTVEVEAAIYASSCFAAQSSSFAISMCAKISDMIESLQVPVPMKLLLIPVLRHMHHEATTASLVSRLCMDLLPKYPAQSFVVAIIDTLTQLSSRTLVGVPGQLDVLLDFMQDLRTPVRIQVLRSFNELAGRQSVHAWPKPAIKALIDRFELCTNSKEQFLFLSILLKLSECPLTCQQLLREHRVALLRLCIQCISKLDDYTTATQAMAVLSVLVAFGLKKKGSGEQVDDILHMVNLHMEGLLLCTAKRSECTRDLRRVLTYGIRITKANAEFGTSFIGIVTNSLGDKGAYPPANAELMCEALAGLCEHFQLRKYAFSTAEDLIVDENAMDTDELPPPKINPMLARLPLILHKLNTIIDQENCDQQLRSVEILSSLVLQTTMGCYLPQKVVQCFEKCLGRLNCWTLYRIARTASRYGHHYVAAHIYTKVSQIVISDHMHYFLVALSQISQAECILNYGLEYAYMRDNYAPKVAPEPLIPLMKRLEMASNLYQQALASLRAGSSPQHPCTFQLEYLKIRAQFLQTLHLAVTVKNAQVIVPPPAIAGSLAQNSRDYLQKFGHVTNQLRKLVKALKACEETYARLYKSSFDADHVTLEFLEVAEFQCALFAHIIESICYATPPEPPVFLTTGDHPETRYFAASCQRMEQMQKNLPQEPANAKTISNRHLDVIIAQIEIITKTPLCLPRYFFQILQSTQIKLSVSPQPRSATEPVNVQSGSNLVIKVEGVLQHFSKQKKHFRRVESVQLSLTSQLITPPPRSSQELPKQGANDTVTLNQIVKPQRDFLSGSFLLPISNGGHFQVTLETFVVDENGITWCTGPKSSMVVRVLEDPSKQGAPAPSTSQAVGQTRRF",
    "output": "Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box-dependent processing . Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5 . Essential for development . Required for cell signaling and/or cell proliferation ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAEGSEKVPIARAGPEDVEQGLPPAYTAAVPPPGPGRLLKAGATVLIAGALLLLAGAIGAFYFWKATERQVYNVHYTMSINGKVQDGSMEIDAGNNLETFKTGSGSEEAVEVHDFQIGITGIRFAGGEKCYIKAQPKARVPEVDAMTKASLSSDLEDEIMPVRFDENSLIWVAADEPIKHNGFLSPKILELCGDLPIFWLRPTYPKDKQRERREMKRNKRQSESNFDAEHRAAAAEEVNTRSTPTQLTQDLGPQSNETRPMQQESDQTLNPDNPYNQLEGEGMAFDPMLDHLGVCCIECRRSYTQCQRICEPLLGYYPWPYNYQGCRTACRIIMPCSWWVARIMGVV",
    "output": "Bifunctional growth regulator. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTTEKRQILVTAALPYANGPIHLGHMVEHIQADIWVRFQRLKGNDCLFICGEDAHGTAIMITAQKQGLPPEALVAKMHKEHARDLGGFLIEYDNFYTTHSPENRELAELIYTRLKDKGDIFAKTISQAYDPVKEIFLPDRFIRGTCPRCGAKDQYGDVCEVCGATYSPTELIDPVSALSGAKPIEKNSEHFFFSLNRYTQLLKKWIDAGHLQPQVANKLKEWFSEDLKPWDISRDAPYFGFEIPHAANKYFYVWLDAPIGYMASLKNLSKQRPSVNFDAYWKEGSQTELYHFVGKDIVYFHALFWPAMLSSAGFRLPTAIYVHGYLTVNGQKMSKSRGTFITAHHYLDHLSPEYLRYYYAAKLSAQVEDIDLNLDDFIQRVNADLIGKYVNLASRCAGFITKNFGGKLANELPEPDLYESFLQTEQTITDYYESLNYSKAVRVIMSLADRANQYIDAKKPWALAKEINQEAQVQAVCTQGLNLFKILTTYLKPILPVTAKKVEQFLNCDELNFANLKTPLLDHSVNPFEPLMQRLLPETAAQLTHE",
    "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLQFVLASASPARRQLLQSIGINPLVYQSNFDESSVAIADHHELVQTLARCKAEVVANQLAAPALVLGCDSVLVLQGKIYGKPKDPADAIARWQSMRGQSGELLTGHTLIDLYQNKTLVRLEITQVDFAWISDRQIAAYVATGEPLNCAGAFALDGRGGLFVDRIVGCPSNVIGLSLPLLRKMLTALGYSPADCW",
    "output": "Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAAKPFFRRRKVCPFSGDNAPKIDYKDTKLLQRYISERGKIVPSRITAVSAKKQRELARAIKRARFLALLPYAVK",
    "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQSLEQCVNSLEAIVHQLDGSVSRLARNGEASNELCEGILKIKRVFELVPEYDVESARLALFEEVDPMVKTLGDKIEKALIRKRRELENLRQTSELNSLRLSGDLYFSETGIDNQDMDVSTDAIAIASATDAELDELRALKARRAELQELLDGR",
    "output": "Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKELQATLDKAEKTLVKVMQEDGTESDFE",
    "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIFATLEHILTHISFSIISIVITTHLMTFAREIAGLSDLSEKGMIAVFLRITGLLVTRWIYSGHLPLSNLYESLIFLSWGFSLIHMISKIQNHKNFLSSITAPSAILTQGFVTSGLLTEMHQSAILVPALQSHWLIMHVSMMLLSYAALLCGSLLSIALLVITFRKKLDIIFLLIRLFSFGEIQYLNEKRSILQNTSFSFRNYHKYQLTQQLDHWSYRVIGIGFTLLTLGILSGAVWANEAWGSYWNWDPKETWAFITWTISAIYLHTRTNKNLQSANSAIVASIGFLIIWICYFGVNLLGIGLHSYGSFALR",
    "output": "Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSIIHGAGAATTTLSTFNSVDSKKLFVAPSRTNLSVRSQRYIVAGSDASKKSFGSGLRVRHSQKLIPNAVATKEADTSASTGHELLLFEALQEGLEEEMDRDPHVCVMGEDVGHYGGSYKVTKGLADKFGDLRVLDTPICENAFTGMGIGAAMTGLRPVIEGMNMGFLLLAFNQISNNCGMLHYTSGGQFTIPVVIRGPGGVGRQLGAEHSQRLESYFQSIPGIQMVACSTPYNAKGLMKAAIRSENPVILFEHVLLYNLKEKIPDEDYVCNLEEAEMVRPGEHITILTYSRMRYHVMQAAKTLVNKGYDPEVIDIRSLKPFDLHTIGNSVKKTHRVLIVEECMRTGGIGASLTAAINENFHDYLDAPVMCLSSQDVPTPYAGTLEEWTVVQPAQIVTAVEQLCQ",
    "output": "The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGYKSDQLLIVVSILEGRHFPKRSRHMLVIDAKFDGEQLSTDPVPHLEQPQFATELAWELDRKTLHQHRLQRTPIKLQCFALDTLTSAKESVGYVVLDLRAAQEKKQAPKWYSLLSSKYTKFKPEIQLNISLETDNKPAVDTFKAKEAPPRRSKVPGDLAGLEPKSLVPILNEAEGYHQIGPAEYCKDYFVLSVTIAFATQLEQLIPSTLRLPEPQPEFFFYYSLLGNDVTNEPFTDLINPEFEPERASVRIRSSKEVLCMYLSVQPKLQIHLCCGDQSLGSTDIALTGLLNKASVEIEHHPVVVEGAFILTPPNRAKQNLSAVPLEMSPTIGVSIALQKEIGLQSVHHPKEQPQSVAAEEVPTTPLKKSANLKEGARSPPPPKPLMFSDSPPTKDEATESEAESIKSDFQAEPPLSKPLTRSKSPPLSEPPLSGSHCPTPIQGVSAIAKNTSESSSAQKITVPPAAHHFCFTIDLRSIRNVDVGFPVNCILRYSYPFFGSAAPIMTNPPVEVQKNMEVFLPQSYCAFDFATLPHQIQDTFLRLPLLVELWHKDKMTKDLLIGVTKIQLSNVLSSEKTRFLGPHGDQCWRQTFSERITVTAVEGSKNKVAELSYIITLEDYGLVKVREVVVSESSQSTGQEKGSLPAQTLQSTAPLPEPRETLEYKAALELEMWKEMQEDLFVNQLKKKELVHMQALAEEWKRRDKEREALVKKKVAEYTVLEEQLQKALADLEKRERQLANDEMELKKLKAQMQLDCERSIQERQDSIRRVREDCMHQIELERSKAKQLEEDKLRLQQQVELERKLESTTKSKLHYKQQWGRALKELARLKQREQENAMARLKKQQQELEHMRLRYLAAEEKDVVKTERQELEEIRNELNR",
    "output": "Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTIHHETRPTLNLIRLANGEGLELPAYESQGAAGMDLRAAVDGDAPLTLPPGKRALVPTGFIFEIPEGFEGQVRPRSGLAFKHGITCLNSPGTVDSDYRGEVKVLLANLGEEAFVIERGMRIAQMVIAPVTQARVAEITAASETARGAGGFGSTGV",
    "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAIANNKKAFHDFFIEDRIEAGLVLEGWEVKAIRAARVQLKESYIYWKKDAFYLVGCHITALPTASTHIKPDAVRPRKLLLNQSEINKLIGKTERAGYTIVPLDLHFSRGKIKMEIGLAKGKKQHDKRQSMKEADWKREKQRLIKHTR",
    "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIVAFCLYKYFPFGGLQRDFMRIASTVAARGHHVRVYTQSWEGDCPKAFELIQVPVKSHTNHGRNAEYYAWVQNHLKEHPADRVVGFNKMPGLDVYFAADVCYAEKVAQEKGFLYRLTSRYRHYAAFERATFEQGKSTKLMMLTDKQIADFQKHYQTEPERFQILPPGIYPDRKYSEQIPNSREIYRQKNGIKEQQNLLLQVGSDFGRKGVDRSIEALASLPESLRHNTLLFVVGQDKPRKFEALAEKLGVRSNVHFFSGRNDVSELMAAADLLLHPAYQEAAGIVLLEAITAGLPVLTTAVCGYAHYIADANCGTVIAEPFSQEQLNEVLRKALTQSPLRMAWAENARHYADTQDLYSLPEKAADIITGGLDG",
    "output": "Involved in the addition of the first glucose residue to the lipopolysaccharide core."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKKVAAQIKLQLPAGKATPAPPVGPALGQHGVNIMEFCKRFNAETADKAGMILPVVITVYEDKSFTFIIKTPPASFLLKKAAGIEKGSSEPKRKIVGKVTRKQIEEIAKTKMPDLNANSLEAAMKIIEGTAKSMGIEVVD",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRAVVQRVTNARVTVSGRTVGQITRPGLVVLVGVTHTDTVRQAHALAVKVHELRILRGELSCAQTGAPILVVSQFTLYGDTRKGRRPSWDAAAPAATAEPLIEAFVAELRRRGAEVATGVFGADMLVELANDGPVTLVLDVD",
    "output": "An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSVMFDPQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGTKHAASTLLVAGVRFMGETAKILSPEKTILMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGNYVQKQTGADVLCWQGACIVHDEFKTQALTRLKKIYPDAALLVHPESPQSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPEKELLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAHEIQVDAALREGALLPLNRMLDFAATLRA",
    "output": "Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKKIRKGDRVVILSGNDKGRSGEVIKVNPGESKALVRGINMVKRHQRQTQKQEAGIISKEAPIHLSNLAIADPKDGKPTRVGFRMNADGGKVRFAKRSGELIDG",
    "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTATLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF",
    "output": "Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) . The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility . In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (Probable). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNKRHSGQRVVVGLSGGVDSAVTAWLLKQQGYEVIGIFMKNWEDDDDSEYCSSNVDFIDAAAVADVIGIEIEHVNFAAEYKDRVFAEFLREYQAGRTPNPDILCNAEIKFKAFLDHALRLGAQKIATGHYARVRCVAADGRVLDAAQAQMSDGRFELLKGLDPSKDQSYFLHRLNQAQLSKTLFPVGELLKTEVRRLALEIGLPNAKKKDSTGICFIGERPFRDFLNRYIAREPGPIKDDKGRTIGQHVGLSFYTLGQRQGLGIGGLKAKGAQRGGGEHAPWFVARKDLATNTLWVVQGHEHPWLQSHGLSAQDASWVAGTAPQAGRFSAKTRYRQLDAPCTLAAGAGAAFHLSFPEPQWAVTPGQSAVLYDDEVCLGGGVIAA",
    "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNITKIKERQKRIRNFSIIAHIDHGKSTLADRILEITGTIDKRVMQTQILDSMDLERERGITIKLNAVQILYQAQNKQQYIMHLIDTPGHVDFSYEVSRSLAACEGAILVIDAAQGIQSQTLANVYLAIENNLTIIPVLNKVDLPSADVPRVKGEIKDILNIDPEMAISASGKTGAGVIDILERIVTQISPPKGDPEAPLQALIFDSYFDPYKGVVPSIRIINGTVKKGDQILFMAGKHVYEVVEVGVYNPKQISKDYLAPGDVGYLTAAIKSINHVSVGDTITSNHKPAIQPLPGYKKMNSVVFCGLYPIEINKYEALKEALEKLKLSDSSLVFEPESSSALGLGFRTGFLGLLHMEIIQERISREFGVEVITTAPSVIYHVYNLKGEKILVDNPSKLPSPQMIERIEEPFIKATIICPEIYIGKVMELSQNKRGSLQNIEYIDQQRTKINYLLPFSETIYNYFDKLKSLTKGYASFDYEMENYRVSKLQKMDILLNGEVVDALSLIVHKDFAYSRGKTICETLKSFIPKQMFEIPIQAALGKKIIARETIKAMRKDVTAKLYGGDVTRKKKLLEKQKKGKKKMKTLGKVDLPQKAFLAILSAK",
    "output": "Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSRILLTGFEPFGGEKVNPSELAVKQLEGKTIAGLEVVAGVLPVVTVKCIDEAVKLIEKYEPVAVLNVGQAGGRVELSIEKVAINVKDYRIPDNEGNQIRYAPVVEGGPDAYFATIPVEKIADSLVEKVIPASVSYTAGTYCCNEVFYGVSHYLRNNKPGVLNGFIHIPFILEQAAGAKPPRASMPLEVIVKGLEIAVEVVAEGLEK",
    "output": "Removes 5-oxoproline from various penultimate amino acid residues except L-proline."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKSAVETLNPTRVRLSIEVPFEELKDSLDAAYKKINQQVTVKGFRKGKIPARVIDQRFGRGAVLEEAVNDALPKFYTEAVNEGELNVLGQPEVDITELKDGELLAFTAEVDVRPEIEIPDYSGIEVTVDALEVTDEEVEKAVEQLRERFAATNPVERAAADGDVVTIDLQAKVDGEVLEDGVADGVSYTIGSGELLDGIDEAVTGLEAGGEATFTSQLKGGSAEGKDAEVTVKVTAVAARELPELDDDFAQMASEFDTLEELKADSRKRLETTKQYDQATQAQERVLEELLKLAEVPIPEKLLADEVQTRKHNLEHHQLGQMGLDLEKYLEIQGKTLEEFENETSEQAIKGIKTQFILDELVNKEKLNVNQEELTEHLMRRAASSGMSPDQFAQAVVEGGQVPMLVGEVARGKALAVVVEAAKVVDTNGEVVDLEDDEEAAEAAAETTEAPAEAAAEDKAEDKKAEEKNEA",
    "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKVTRAALYQLFTALNVFGRVYLAHEGMNAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDDGKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYEYEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGFNKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDSHTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNKSRGRLNTTLGIPEPTE",
    "output": "Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARIAGVDLPKKKRIEYGLTYIYGIGLFTSRKILDKVGISYDKRVHELSEDEAAAIRKEIQENYMVEGDLRKQVAMDIKALMDLGSFRGLRHRKGLPVRGQKTKTNARTRKGKRKTVGAKS",
    "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTNIRKSHPLFKIINDSLIDLPAPSSISSWWNFGSLLGICLAIQILTGLFLAMHYTSDTTTAFQSVTHICRDVNYGWILRYLHANGASMFFICLFLHVGRGLYYGSYIYKETWNVGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIISALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDMLGALAMILVLMTLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILIVMPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVLMPITSIVENHLLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNAPDRFELFLLGEGESKLKIDPDTKAPNAVVITFEKEDHTLGNLIRAELLNDRKVLFAAYKVEHPFFARFKLRIQTTEGYDPKDALKNACNSIINKLGALKTNFETEWNLQTLAADDAF",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft. Seems to be involved transcript termination."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTIEDRGDAHVITHSLAKHTLSRLRDTTTEQVSFRKGLVKLGRISGYEIIDGAMETEFTAFETPLTETTGERVTGLDDVVIINVLRAATPFVEGLLKAFPRAKQGVISAGRDEDAGMDADGEFPITVDYVKLPDISEGDTVIVADPMLATGSTMCTVLDHVTDEMPAAGVEDLFVLSAVSAPDGLLRVGDQFPDADLLTVAIDDTLTDDGYIVPGLGDAGDRAFRTT",
    "output": "Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIPFSLKNGTLCVEDIPLPEIAAQYGTPCYVYSHSYLTERARRFTKALDGAGKGKSLVAFAVKANPSQAILASFAKEGLGADVVSAGEIRRAVHAGIPPERIVFSGVGKTAEEMRYALEIGIGQFNIESVSEIEMLAEVATSLGKKAAVALRINPDVDPHTHAKIATGKADTKFGIAAEDALSAYEKLASYPSLKIQGIASHIGSQITDLAPFEAAAERIYEIITALEKAGHAIETADLGGGLGVRYKDDQPEPPSVEAYGEMIKRVTKGWNCRLIFEPGRSLIANAGVLLSKVIRIKESKTARFVILDAAMNDLVRPTLYDAYHEIKAVTPSAQTYQADIVGPVCETGDIFARNRSISAVKADDLMAIMSAGAYGATMASAYNSRPLVAEVMVSGNKSALIRKRQSVEDLMRDEQKVEWL",
    "output": "Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKSWDVIVIGGGHAGCEAAAASARAGARTLLLTHKLETIGEMSCNPAIGGLGKGHLVREIDALDGVMGRMADKAGIQFRMLNRSKGPAVRGPRSQIDRRLYREAMQAELFSTGNLDIIAAAAEDLIVEDGKVAGAVDAAGQAYRAPRVILTTGTFLKGVIHRGEDRIPAGRVGDQPAIGLSDRLYGLGFQMGRLKTGTPARLDGKTIAWDRLESQAADDTPVPFSYLNHRIDVPQIACGVTYTTEETHRIIAERIGESLVYSGRATGVGPRYCPSIEDKVVRFADKTSHQIFLEPEGLDDDTVYPNGISTSVSEETQLLFLRTIPGLEQVEVIRYGYAIEYDYVDPRELYPTLETKRLPGLYLAGQINGTTGYEEAGAQGLVAGLNAALAVQGREPAIFARDEAYIGVMIDDLVTRGVTEPYRMFTSRAEFRLTLRADNADQRLSDRGISLGVVGPVRAAAWTEKKARLDAARAFARSVTLTPNEAVKAGFKVNSDGVRRDVFAMLAYPDVTLDDLGRIWPEVFTWNTDVREQIEIEAAYAGYLDRQRADAESLRKDEDLRLPADLDYAEIGSLSNEVRGKLARVRPLTLGQAARIEGVTPGALTALLAHVRRGRAA",
    "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAITAAASRLGTSAFSDAPPVELRANWSEEDLETVIRAVYRQVLGNDYVMASERLVSAESLLRNGKITVREFVRAVAKSELYKEKFLYGNFQTRVIELNYKHLLGRAPYDESEVIFHLDLYENEGFDADIDSYIDSPEYTNSFGDWVVPYYRGFNTQPGQKTVGFNRIFRLYRGYANSDRAQAEGSMSRLARDLATNRANTVVPPSNSDTAFAYYTPSADVPPRACLGGSFGESGRVYRIEVAGIRQPGYPGVRRSSTAFLVPYEQLSAKMQQLQRTGARIISVNPA",
    "output": "Rod linker protein, associated with phycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALAVLHVLEPFPTETPPLAVLLPPGGPWPVTGVGLVLALRPASESPAGPALLVAAVEGSGAQCEQRGPGPPPLLVSRTLLRVLALSPGARVRARPVRRPPALGWALLGTSPGPGLGPRVGPLLVRRGETLPVPGSRVLETRPALQGLLGPGTRLAVTELQGRTKLDPESRDHNHPPPPPVVSSFAVSHSIRQLRGVLGGTGDALGVSRSCLRSLGLFQGEWVWVARVGELPNTSQPHLAQVQVLEPRWDLSARLGPNSGQPGEPLADGLVFVPATLAFNLGCDPLEVGELRIQRYLEDSTAAEDKGSCSLLPGPPFARELHIEVLPSPHCGVNGKYDHVLYQHFHTPRVVQEGDVLCVSTAGQVEILEGSLERLPRWREVFFKVKKTVGEAPDGPASAFLADTTHTSLYLAGTTLSRVPPLPSGRSPPWDSLSPPGLEALVNELCAVLKPHLQPGGTLLTGTSCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVVLLLTALDLLGRDRDGLGEDARVVATLRHLLLDEDPLSRCPPLMVVATTSRVQDLPTDVRTAFPHELEVPVLSESQRLSVLQALTAHLPLGQEVNLSQLARRCAGFVVGDLYALLTHASRAACTRIKAAGLAMSEEDEGELCAAGFPLLAEDFGQALDQLQTAHSQAVGAPKIPSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGASEDRASQLRVLSAITRKFKLEASVSLMNVLDCCPPQLTGADLYSLCSDAMMTALKRRVRDLEEGLEPRSSALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKFAAC",
    "output": "Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSYIVRFTGLLLLNAFIVRGRPVGGIQH",
    "output": "Involved in control of the biosynthesis of leucine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGRLPVLLLWLAWWLSQAGIACGAGSVRLAGGLTLGGLFPVHARGAAGRACGALKKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGRGDGDEASVRCPGGVPPLRSAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIAQSIKIPREPKPGEFHKVIRRLMETPNARGIIIFANEDDIRRVLEATRQANLTGHFLWVGSDSWGSKISPILNLEEEAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEFWEENFNCKLTSSGGQSDDSTRKCTGEERIGQDSAYEQEGKVQFVIDAVYAIAHALHSMHQALCPGHTGLCPAMEPTDGRTLLHYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGGYQAVGQWAEALRLDMEVLRWSGDPHEVPPSQCSLPCGPGERKKMVKGVPCCWHCEACDGYRFQVDEFTCEACPGDMRPTPNHTGCRPTPVVRLTWSSPWAALPLLLAVLGIMATTTIMATFMRHNDTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPCAAICAARRLLLGLGTTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFGLTSLQVVGVIAWLGAQPPHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFNEAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVILFHPEQNVQKRKRSLKKTSTMAAPPQNENAEDAK",
    "output": "G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSENVPSFRWTQSLRRGLSNWTHAVKGDVLADARAIVSALDFHQVAQVQRMMRKDKRSEADLTRLRDMNKEVDALMMMRSAQKDNILKVGGLSKDELMELASDLDKLRKKVQRTEGGGQPGVYAGNLTSSQLNQRSEILKMMGMGTGPRGPVGGVVKVWDIKDSSLLVNQFGSMPALTIACMTQQGGEQMNDVVQALTSLGLVYTVKYPNLSDLEKLTEKHPCLKLITQEPAQINISGYNLSLSAAVKADACMIDGGNMLETLQVKPSMFSTLIKTILEVKNREGMFVSPSPGQRNPYENILYKVCLSGDGWPYIGSRSQIKGRAWENTTVDLEGKPSVNHPPVRNGGSPDLKQIPKTKEDEVIRAIEQLDPRGTTWVDIEGPPGDPVELALFQPETGNYLHCYRRPHNENAFKDQSKFSHGLLLKDLADTQPGLISCIIRHLPNNMVLTAQGNDDIIKLLEMHGRRDIKVLDVKLSSDQARLMEDVVWERYNMLCVKHTGLVIKKKKKGAAPGSANPHCALLDCIMFDATVTGYLRDQKPKRLLPLDTLYRDNANLINL",
    "output": "Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MATIHVDGKTLEVDGADNLLQACLSLGLDIPYFCWHPALGSVGACRQCAVKQYTDENDKRGRLVMSCMTPATDNTWISIEDEEAKQFRASVVEWLMTNHPHDCPVCEEGGHCHLQDMTVMTGHNERRYRFTKRTHQNQELGPFIAHEMNRCIACYRCVRYYKDYAGGTDLGVYGAHDNVYFGRVEDGVLESEFSGNLTEVCPTGVFTDKTHSERYNRKWDMQFAPSICHGCSSGCNISPGERYGEIRRIENRYNGSVNHYFLCDRGRFGYGYVNREDRPRQPLLVLSKQKLSLDGALDQAAALLKERKVVGIGSPRASLESNFALRELVGEGNFYSGINEGELDRLRLILQVMQEGPLPVPSIRDIEDHDAVFVLGEDLTQTAARIALALRQSVKGKAVEMAADMKVQPWLDAAVKNIAQHAQNPLFIASVSATRLDDVAEETVHAAPDDLARLGFAVAHAIDPSAPSVADLDPQAQAFAQRITDALLAAKRPLVVSGNSLGNKALIEAAANIAKALKQREKNGSISLVVGEANSLGLALFGGDSVEAALERLTSGQADAVVVLENDLYRRTDAARVDAALAAAKVVIVADHQQTATTAKAHLVLPAASFAEGDGTLVSQEGRAQRFFQVFDPTYYDARNMVREGWRWLHAIHSTLQGKRVDWTQLDHVTEAVAEAKPILAGIRDAAPAASFRIKGLKLAREPHRYSGRTAMRANISVHEPRTPQDIDSAFAFSMEGYSGSQEDRQQIPFAWSPGWNSPQAWNKFQDEVGGHLRAGDPGVRLIEPKGEGLDWFQAVPVPFSAKADSWKVVPLYHLFGSEENSSRAAPIQQRIPETYVALSKEDADRLGVNDGATLGFQLKGQALRLPLRIDEQLGAGLIGLPVGFAGIPAAIAGCSVEGLQEAAQ",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFFNKKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKIKTVVSSSEDSTRKLKALGFDVVDLNYAGEIDLYIDGADECNNHKELIKGGGAALTREKICVAAAKKFICIIDESKKVNTLGNFPLPIEVIPMARSYIARQIVKLGGQPVYREQTITDNGNVILDVYNLKIDNPLKLETELNQITGVVTNGIFALKPADTVIMATKDSNIVVL",
    "output": "Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "QEGDPEAGAKAFNQCQTCHVIVDDSGTTIAGRNAKTGPNLYGVVGRTAGTQADFKGYGEGMKEAGAKGLAWDEEHFVQYVQDPTKFLKEYTGDAKAKGKMTFKLKKEADAHNIWAYLQQVAVRP",
    "output": "Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "VFCRFNGQQCTSDGQCCYGKCRTAFLRMICMGG",
    "output": "Acts as a neurotoxin."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGVAFDKCETRPANIDAILSGLDRYNPETTTIFQDYVVQQCEDRTFDCYANLALLKLYQFNPHLLQAETVTNILAKALTVFPSPAFSLCLSLLPAHTQPFPSNTEAQAASQTSDFVESVQKLARLSTLLESAQYAQFWSTLNSDDLYADLTADVAGFEELVRIRIAVEVGKAFREINAEVLEQWLDLRSREALEKFVAEVCSWEVDKSGPNGTVVKVPTNKENEVRSEVKSERVGVEMFGRVIRRGFEQAA",
    "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEQVIPKVPERPRRRITRSEEPEQLRSESEFEREKSGSKDSELDLPPVPKTRPNRKPLASSSAHASSDDVSVKPEPQIQAQLQPEAVIETEPTVEHPIVDELEAKLPVEQPVLDEVELDEPVTQEVEPSGELLPEESTIKESLEEQIIDDFADEPVEEECKEVASPELIGDEAIQDEELEKPVKEEPIIQTDDKTLAEAIVPSVCEESEADIAEEPKETPEDASEAVVEAAREESSEVSPEASPEVPPEKTQVSVDQLSSTANLTEGAKEAPKEEQKETSEATSEETPEDSSVNAKPLFKEVTPGNVSSKEAIPSNTSPKEGSPATQKKKQGKSPPVPKKPSSKIAAFQQMFQNQQLQPEHTPSPKEPAAPKTGGFSGNRAQFAQNLNGMIALPGMAQLTPALAKRLGVSTSSDDAETGAEVETKNTKDEAELPKVPARSKKTRGPHKRLPKTVASIEKVETKSTSNISVVKAWTISFKPDLPERADDQPMEAELTAGEAIAPSEPAGLEDVEAEDLNEASPEEPLQIISESGNSDESEIQHTSDPSIAQNVEHEEEVHEEAEAAPEAEPEAEEIALDTEESNPTAFIAETYDEDTEVETPTA",
    "output": "Involved in mitochondrial migration along actin filaments."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNKEEILEAIKNMTVLELAELVKALEEEFGVSAAAPVAVAAAPAAGAPAAAPAEEKTEFDVILQEVGSDKIKVIKVVREVTGLGLKEAKDLVESAPKPVKEGVSKDEANQIKAKFEEVGAKVEIK",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTHSLRVIFAGTPEFAAAALAAIHEAGFPVPLVLTQPDRPAGRGMKLQASAVKRYALERGMAVAQPPSLRRAGKYPAEAVAALDLLHATPHDVMVVAAYGLLLPQEVLELPRHGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDAGLDTGAMLHEARVAIAPDDTTATLHDKLAAAGARLVVDALVELERTGALAATPQPADGVTYAEKIGKHEAALDWRKPAAALARQVRAFDPFPGGAGTLDGATLKLWAADAVPGRDDAAPGTIVDIGPDGVVIACGEGALRVTQLQKPGGKRLPAREFLAGAPLAVGQRFAPADAA",
    "output": "Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNPGRLGLAPLLQENPLWISWHDSNWIPVLNPGNVMDYFSEKSNPFYDRTCNNEIVRMQRQSLELLNNMTGVEYIPLHVQDPILYVIRKQHRHSPTEATPMADYYIIAGTVYQAPDLASVFNSRILSTVHHLQTAFDEASSYSRYHPSKGYSWDFSSNKAIAEKTKTQTKKEAPVKEEPSSIFQRQRVDMLLGDLLRKFPLPLPQMTNNPTGGNPSDTANASNNHGGAAGDSDHVGADATLIKQEPTEGGVGRAGNNDVPPEKKMKL",
    "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIGGKKKCIGLIFGGNSNEHEVSISSAKTVFQAFKSEINKERFTIRAFYINKYGDWLDSDSSEKILIDESKNKNTTKKQIFNQEKINFLDGVDFQNVDVWFPLLHGINGEDGSIHGLLRFTKKPLVGCGIIGSALGMDKILMKIIFSNLKIPQVNYLVFQNQDLNDEEVKNKLIHEILKKLNFPVFVKPSNSGSSLGISKVINKSEIIPALEKARGIDPSILIEEGLEVREIECGIIGNSKLLTSEIGEVNYKSDWYDYNSKYHSNNKIIIPAEIDSKISKEIKEIAIKSCRALNIFGFARVDFFLEKSSNKIFLNEINTIPGFTKNSMFPMLWKASGLKIEQLVAKLVDISLDL",
    "output": "Cell wall formation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAVTMADITKLRKMTGAGMMDCKNALTDAEGDFDKAMKIIREKGQAVAAKRSDREASEGCVLVKVEEGFGAIIALKCETDFVAQNADFVKLTQDILDAAVANKCKTLEEVLALPMGDATVAQAVTDRTGITGEKMELDGYMVLEGATIAAYNHMNRNGLCTMVAFNKKVDEQLAKQVAMQVAAMNPIAVDEDGVSEEVKQKEIEVAVEKTKVEQVQKAVEAALKKANINPAHVDSEDHMESNMAKGWITAEDVAKAKEIIATVSAEKAANMPEQMIQNIAKGRLAKFLKEVCLLNQEDIMDAKKTVREVLKEADPELKVVDFKRFTLRAE",
    "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSDNSQKKVIVGMSGGVDSSVSAYLLQQQGYHVEGLFMKNWEEDDDTEYCSAATDLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLEEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRHDVDGKSRLLRGMDGNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEELELATAKKKDSTGICFIGERKFTDFLARYLPAQPGPILSVDDNKPMGQHQGLMYHTLGQRKGLGIGGVKDGGEDPWYVVDKDVANNILYVAQGHEHPRLMSHGLIAQQLHWVDRQPLTAELRCTVKTRYRQADIPCTVTPLGDDRITVRFDEPVAAVTPGQSAVFYLDDVCLGGGIIEERLQE",
    "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPLPQPLLGGASPAPARAASSFLHPLLHTRHRVSTAPAAASSFVPASHSSHANDAMLLRRAADVADRSAGLTSPHPNFGCVIARPQLNTDSADSWVVGEGFLYAQGTPCAELLASQEAGEHARGGTAYLNLEPGDCFGDNTAVGSLVQAGITRVVVGLRHPLKHLRGKAIQALRNEGIQVDVVGEDLQSKLFKEALKSCLTVNAPLLYRAAFHVPFSVLKYAMTADGKIAASSGHASWISGKASRGRVFELRGRSDAVIVGGNTVRFDDPRLTARHVKGHVPVRIVMSQSLNLPEEANLWNLNDAYTIVATQRGARRDFQRKLAMKGVEVVEFDMLNPRAVMSYCYDRGYLAVLWECGGTLAASAISASVIHKVYAFWAPKIIGGLNAPTPVGELGMSQMTQAINLIDVSYEQIDRDMLMSGFIEPIPDLSPVIPSVEEIPSIDPEVSPYETNIISFYKTWDIFGAFSNFSPHSIQMPDENGDYFTWPTVEHYYQAHKFVGVDNPQARDIVQEIKLAKSPEEAARIGRTRQKGFPELVRTDWESTKIDVMYRAIKCKFSTYPHLTNMLLSTAGSVLVEASPHDLFWGGGREGEGLNYLGRLLMQLRSEILGTVPASAEVGEAD",
    "output": "Pyrimidine reductase involved in the riboflavin biosynthesis pathway. Has also a non-functional N-terminal deaminase domain that lacks the catalytically essential zinc-binding residues. 39% activity when NADH replaces NADPH. No evidence for a phosphatase activity conferred by the N-terminal domain.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNAPLKADDTDLAALMADLATKARAAARVLALAPAEQKNTGLAAMAAALRASAPKLLAANAEDVAEARASGATPAFVDRLALNDARIETMAAGLDVVRGLDDPVGKVTERWTRPNGMTIERVRVPLGVAAVIFESRPNVLADAGALCLKSGNAVILRGGSDSFRSCQAIHACLTQGLREAGLPEAAISLVPTRDRAAVGLLLSGLDGRIDVIVPRGGKSLVARVEAEARVPVFAHLDGNNHVFVDKAASLDMAKTIVLNAKMRRPGICGAAETLLVDKAAAPAQLKPLVGMLIDAGCEVRGDTDVQKADARVTPVTEDDWATEFEAPIIAAKVVGGLDEAIAHIERYGSHHTDAIVTDDATAATRFLNEVDSAIVLHNASTQFADGGEFGFGAEIGIATGKFHARGPVGVEQLTSFKYRVHGTGQTRP",
    "output": "Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDKAFDEIIGNSHTDSSSNHKVTRYRRRDLRNELGPRLGFAPSDAASRSKDRLYREREEPPLPKRIRISKIPLDVSDYTLDDMIKEFGSPIFSKIFDNKEDRTCIYEFEDPEVLEKIVERYNGHELHNAKIEVEIYQPQRKHSRMNAHNRRKQTAQEHGRDRPGSHYRQKPNRVSKKNKGREKNNTPTSVEALDAELDAYMKG",
    "output": "Involved in export of poly(A) mRNAs from the nucleus. Recruited to the coding sequences as well as poly-A sites of active genes (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAAKDVKFGDDARQKMLVGVNVLADAVKTTLGPKGRNVVLDKAFGAPTVTKDGVSVAKEIELKDKFENMGAQMVKEVASKASDDAGDGTTTATVLAQAIVNEGLKSVAAGMNPMDLKRGIDKAVAAAVEFVKSSAQPCEDSKSIAQVGTISANSDSHIGDIIAEAMEKVGKEGVITVEEGSGLENELDVVEGMQFDRGYLSPYFITNQDNMSVEHESPFILLVDKKISNIRELLPVLEAVAKAGKPLVIVAEDVEGEALATLVVNNMRGIVKVAACKAPGFGDRRKAMLQDIAILTGGTVISEEVGLDLESATLEHLGQAKRFTMSKENSVIVDGAGSADDIKARVNQIRKQIEETSSEYDAEKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVSLMRAVAAIADLQGENEDQTAGVAIARRAMEAPLRQIVTNAGEEASVVAEKVRGGEGNFGYNAGSGVYGDMLEMGILDPAKVTRTALQAAGSIAGLMITTEAMVADKPEDKAGPAVPDMGGMGGMGGMM",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI",
    "output": "Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSIEHTSHDPSKPDPAKARTLAAALPWLKRYHGKIVVVKYGGNAMTDETLKRAFAEDIAFLRFAGFKPVVVHGGGPQISTMLDRLGIRSEFRGGLRVTTPEAMDVVRMVLVGQVQRELVGLINEHGPLAVGCSGEDAGLFTAEPANTVIDGEEVDLGLVGEVARVRPESVLDLIEAGRIPVVSSVAPDADGQVHNVNADSAAAALAVALGAEKLLVLTDVEGLYLDWPSSDDVIGEISPEALEEILPTLASGMVPKMGACLQAVRNGVPRATVVDGREPHAVLLELFTNEGVGTQVLPGVETKTRKARDTQS",
    "output": "Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF",
    "output": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLNTPRICVVVIGKTLEEFLSQLEAAQTAVDFVELRIDYLEQINPNWVRIIKNHTHKKAILCCRARADGGKFLGTPEAQQEILQAGNDLGFDYLDIDLPVANKISIHEKKAKIIISYHNFLHTPPITELNFLLENMRLFNPDVFKFATKSEQYEDVKTLFKLLINKKNNENMIVLGMGEQGKIIRLLSPLLGGYLTFSSINGAISAPGQIDFKTMQDFYQRFYKISSPLKGED",
    "output": "Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKILIINTGSSSLKFAIYQYENSKKIISGIVEKIKSQKSIIKIVNTDGSTTERFEKGIENHQKAIEKMFKILTNSDLKILKTLSEIKIIGHRVVHGGSSLKNSVILNNSILNKLKQISELAPLHNPNAITAIEAVLKILPHAKQVLCFDTSWHQTIKEHAFLYAIPYSWYKNHNIRKYGFHGLSYSYITKRSSEILNKKIDSLNLIILHLGNGASINAVKNGKSYDTSMGITPLEGLAMGTRSGDIDPSIINLMSTILNKTTKQIEEILNKESGILGISEKSNDMRDIWNKIEEGEYQSKLAVEIMTYRIKKYIGSYIAALDFNVDAIVFTGGIGVTDYGIRALALKGFEKIGIELDLEKNEMAQSKYLESEISTINSKLKILAIPTNEESTILEDIYNLIPKNL",
    "output": "Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSGPFPAEPTKGPLAMQPAPKVNLKRTSSLVGPTQSFFMRESKALGAVQIMNGLFHITLGGLLMIPTGVFAPICLSVWYPLWGGIMYIISGSLLAAAAEKTSRKSLVKAKVIMSSLSLFAAISGIILSIMDILNMTLSHFLKMRRLELIQTSKPYVDIYDCEPSNSSEKNSPSTQYCNSIQSVFLGILSAMLISAFFQKLVTAGIVENEWKRMCTRSKSNVVLLSAGEKNEQTIKMKEEIIELSGVSSQPKNEEEIEIIPVQEEEEEEAEINFPAPPQEQESLPVENEIAP",
    "output": "B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTAVASTSGKQDADHNQSIECPRFSRGQKEILLDHEDAKGKDSIINSPVSGRQSISPTLSNATTTTTKSIMNATGTSGAVVSNTPEPGLKRVPAVTFSDLKQQQKQDSLTQLKNDSERTKSPNSNPAPVSNSIPGNHAVIPNHTNTSRTTQLSGSPLVNEMKDYDPKKKDSALKIVDTMKPDKIMATSTPISRENNKVTAKAPTSITLRKEDAQDQANNVSGQINVRSTPEETPVKQSVIPSIIPKRENSKNLDPRLPQDDGKLHVLFGATGSLSVFKIKPMIKKLEEIYGRDRISIQVILTQSATQFFEQRYTKKIIKSSEKLNKMSQYESTPATPVTPTPGQCNMAQVVELPPHIQLWTDQDEWDAWKQRTDPVLHIELRRWADILVVAPLTANTLSKIALGLCDNLLTSVIRAWNPSYPILLAPSMVSSTFNSMMTKKQLQTIKEEMSWVTVFKPSEKVMDINGDIGLGGMMDWNEIVNKIVMKLGGYPKNNEEEDDDEDEEEDDDEEEDTEDKNENNNDDDDDDDDDDDDDDDDDDDDDDDDEDEDEAETPGIIDKHQ",
    "output": "Component of the phosphopantothenoylcysteine decarboxylase (PPCDC) involved in the coenzyme A synthesis. Acts as an inhibitory subunit of protein phosphatase PPZ1, which is involved in many cellular processes such as G1-S transition or salt tolerance. Also modulates the expression of the ENA1 ATPase."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSGETTRLTEPQLRELAARGAAELDGATATDMLRWTDETFGDIGGAGGGVSGHRGWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIGTRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPLGKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDVQEYIADNDVLVNPLVREGYPSIGCAPCTAKPAEGADPRSGRWQGLAKTECGLHAS",
    "output": "Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSTSLAVVRLDRELPMPTRAHDGDAGVDLYSAENVELAPGQRALVSTGIAVAIPHGMVGLVHPRSGLAARVGLSIVNSPGTIDAGYRGEIKVSLINLDPQTPVVISRGDRIAQLLVQRVELPELVEVTSFDEAGLADTTRGDGGHGSSGGHASL",
    "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVLLAAAVCTKAGKAIVSRQFVEMTRTRIEGLLAAFPKLMNTGKQHTFVETESVRYVYQPMEKLYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALGYRENVNLAQIRTFTEMDSHEEKVFRAVRETQEREAKAEMRRKAKELQQARRDAERQGKKAPGFGGFGSSAVSGGSTAAMITETIIETDKPKVAPAPARPSGPSKALKLGAKGKEVDNFVDKLKSEGETIMSSSMGKRTSEASKMHAPPINMESVHMKIEEKITLTCGRDGGLQNMELHGMIMLRISDDKYGRIRLHVENEDKKGVQLQTHPNVDKKLFTAESLIGLKNPEKSFPVNSDVGVLKWRLQTTEESFIPLTINCWPSESGNGCDVNIEYELQEDNLELNDVVITIPLPSGVGAPVIGEIDGEYRHDSRRNTLEWCLPVIDAKNKSGSLEFSIAGQPNDFFPVQVSFVSKKNYCNIQVTKVTQVDGNSPVRFSTETTFLVDKYEIL",
    "output": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTHRTKTRPVKVGNLTIGGNNELIIQSMTTTKTHDVEATVAEIKRLEEAGCQVVRVAVPDERAANAIADIKKQINIPLVADIHFDYRLALKAIEGGIDKVRINPGNIGRRHKVEAVVNAAKERGIPIRIGVNAGSLERHILEKYGYPTADGMVESALHHIKILEDLDFHDIIVSMKASDVNLAIEAYEKAARAFDYPLHLGITESGTLFAGTVKSAAGLGAILSKGIGNTLRISLSADPVEEVKVARELLKSFGLASNAATLISCPTCGRIEIDLISIANEVEEYISTLQVPIKVAVLGCAVNGPGEAREADIGIAGARGEGLLFRKGQVVRKVPEEIMVEELKKEIDVIAAEMAAEREKEKETQEQ",
    "output": "Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSGPRSASPPGCAATRGGPEHRAAWGEAEARANGHPHAAGGATRGCSKKPGGAVTPQLQQQQQQQQHEQQHEQQQHEQQQHVQQQQRLAKRWRGDDDPPLGGDDPLAGGFGFSFRSRSAWQERGGDDCGRGSRRRRRGAAGGGSSRAPPAGGGGGPAAAGGAEVRPRSVELGLDERRGRGRAEPEPEAEAGAPGGDRGARDGDGPAGPGACCRALLQIFRSKKFPSDKLERLYQRYFFRLNQSSLTMLMAVLVLVCLVMLAFHAARPPLRLPHLAVLAAAVGVILVMAVLCNRAAFHQDHMGLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHLAIALRANAQDRFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLSYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITIVPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPGPLQSLSRKIVRSKTNSTLVGVFTITLVFLSAFVNMFMCNSEDLLGCLADEHNISTSRVNACHVAASAANLSLGDEQGFCGTPWPSCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPRVTLFDNADLLVTANAIDFNNNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRVLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS",
    "output": "[Isoform 1]: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling . Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion (By similarity).; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKIEEKLFQDRYRVDSGRPHIRIKDPDHCTELSEKQCTVCCPAGCYTRETNGKVTLVTDGCLECGTCRIICQDSGNLEWEWPRGGFGILFKFG",
    "output": "Could be a 3Fe-4S cluster-containing protein."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSEMTPREIVHELNRHIIGQDNAKRSVAIALRNRWRRMQLEESLRVEVSPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVETIIRDLTDVAIKMTHQQAMEKVQYRAEEQAEERILDALLPPARDAWGQNEQSTEDTTSSNTRQIFRKKLREGKLDDKEIEVDVAAPQMGVEIMSPPGMEEMTNQLQGMFQNLAGDTKKKRKMKIKDAFKALTEEEAAKLVNQEELKESAIFNAENNGIVFIDEIDKICKRGDSSGPDVSREGVQRDLLPLIEGSTVSTKHGMVKTDHILFITSGAFQVAKPSDLIPELQGRLPIRVELEALSAHDFKRILTEPKASLTEQYIALMKTEDVGIEFTEDGINQIADAAWRVNETTENIGARRLHTVMERLMDEISFDATDRAGSKLVIDEAYVISKLGELVEDEDLSRFIL",
    "output": "ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPAVDPYDMPGTSYSTPGLSAYSTGGASGSGGPSTSTTTSGPVSARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSTSAKEDGFGWLLPPPPPPPLPFQSSRDAPPNLTASLFTHSEVQVLGDPFPVVSPSYTSSFVLTCPEVSAFAGAQRTSGSEQPSDPLNSPSLLAL",
    "output": "Heterodimerizes with proteins of the JUN family to form an AP-1 transcription factor complex, thereby enhancing their DNA binding activity to gene promoters containing an AP-1 consensus sequence 5'-TGA[GC]TCA-3' and enhancing their transcriptional activity . As part of the AP-1 complex, facilitates enhancer selection together with cell-type-specific transcription factors by collaboratively binding to nucleosomal enhancers and recruiting the SWI/SNF (BAF) chromatin remodeling complex to establish accessible chromatin . Together with JUN, plays a role in activation-induced cell death of T cells by binding to the AP-1 promoter site of FASLG/CD95L, and inducing its transcription in response to activation of the TCR/CD3 signaling pathway (By similarity). Exhibits transactivation activity in vitro . Involved in the display of nurturing behavior towards newborns . May play a role in neurogenesis in the hippocampus and in learning and memory-related tasks by regulating the expression of various genes involved in neurogenesis, depression and epilepsy . Implicated in behavioral responses related to morphine reward and spatial memory .; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSEKENNFPPLPKFIPVKPCFYQNFSDEIPVEHQVLVKRIYRLWMFYCATLGVNLIACLAWWIGGGSGTNFGLAFVWLLLFTPCGYVCWFRPVYKAFRADSSFNFMAFFFIFGAQFVLTVIQAIGFSGWGACGWLSAIGFFQYSPGAAVVMLLPAIMFSVSAAMMAIAIMKVHRIYRGAGGSFQKAQTEWNTGTWRNPPSREAQYNNFSGNSLPEYPTVPSYPGSGQWP",
    "output": "Probably involved in membrane protein trafficking."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEPMSVKEDLRLFQSTLLQDGLKELLKENKFVDCILKVGDRSLPCHRLIMAACSPYFRELYFTEDGTEKKDANKEVVLENVDPNIMDMIVNYLYSADIDITDDNVQDVFAVANKFQIPSVFTVCVNYLQNKLSLGNCLAIFRMGLVLNCPRLAVSARDFIAEHFETLSKDEEFLEFNAPEFFAIIGCDALNVEKEELVFELLMKWVRKNKENRAKALGDAFEHIRFRLLPEKYLKEKVEKDDIIKADPELIKKLKVIKDAFAGKLPQIKEGEKEGEGENELPGFLNDSQRLGMFNRDLILMINDTAAVAYDANENECFLAAMAEQIPRNHVSITSKKNLLYVAGGLFVDEENKDSPLQCYFYQMDPHSPNWIALPPMPSPRCLFAMGEFENLLFAVAGKDLQSNESLDSVLCYDVDKMKWLETKKLPLRIHGHSVISQNGLVYCIGGKTDENKTINKMFAYNHKKSEWKELAAMKTPRSMFGATVHKGKIVVVGGVNEDGLLSSCEAYDFGTNKWEVFAEFAQERSSVNVLSVDGVLYAVAGFTIKENEDKQCVPSEITDIWQYEEDKKQWSGMIGEMRYASGASCVSMRLNVAKMPKL",
    "output": "Involved in skeletal muscle development and differentiation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVNVFVDGLSVEVKKGATILQACAQVGIEIPRFCYHERLSIAGNCRMCLVEVEKSPKPVASCAMPVMDNMKIFTNTPLVKKAREGVLEFLLVNHPLDCPICDQGGECDLQDLTMVYGSDRGRFHEYKRGVEDKNIGPLVKTVMTRCIHCTRCVRFATEVAGVPDLGTVGRGRDTEISTYIQKVFNSELSGNVIDLCPVGALTSKPYAFTARSWELQSTESIDVSDAIGSNIRIDVRGSEIMRILPRLNEDVNEEWISDKARFCYDGLKRQRLNNPIIKENGQYKTVTWEKAFNFILKNLQEIQNSNRIVGVVGNLMDVESILLFKELLNKLGSSKIYLESSTPILQLNDDEKEDQILNNADFRNNYISNTPLAKIEESDLCLLIGTNIRLEAPLLNTRIRKRYLQGNYSVYSVGPTNNLTYNTENLGNDISTLLEISEGRHPFCKKLMKSKKPLIIIGTHVLQRTDGTSIIELVKTLFKYTQIKTSNWNGFNILHTSASSVGALDLGIGSTKRYSEKISNSKIEKHFIYLLGADEIRIENSKEHFIVYQGHHGDYGANIADVILPGSAYTEKTATYVNVEGRVQNTKSAFYAPGNAREDWKIIRALSEVLNKKLPYDSFEDIHTRFMSIAPHLLKVNAIEKNKIVIENSLPFKGLIKNIGFKPLFNNFYLTNAICRSSQTMAKCSSIYKLN",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNSTWDGNQSSHPFCLLALGYLETVRFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHSTSYFIQTMAYADLLVGVSCLVPSLSLLYYPLPIEEAMTCQVFGFVVSVLKSISMASLACISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCAESWHTNSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTKEISERQARFSSQNGETGEPQTCPDKRYAMVLFRITSVFYVLWLPYIIYFLLESSTGCSSRLASFLTTWLAISNSFCNCIIYSLSNSVFQRGLKGLSGSLCTSCASHTTAKDPYTVRCKGPPNGSHI",
    "output": "Orphan receptor."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPQSPEQPDVSSTVSYNRVMLKISGEALMGTQGFGLHPPTVRRIAEEVKSVHDLGVEICMVIGGGNIFRGLSGSAQGMERTTADYMGMLATVMNALGMQSALEDLGVFTRVISAIRMDEVAEPYIRRRAVRHLEKKRVCIFAAGTGNPYFTTDTAATLRANEMNCEAIFMGKNGVDGVYDKDPKTNEDAKRYDSVSYDDVLAKRLKVMDASAIALARDNNLPLIVFGLDEPGGFRGVLAGEGTYTKVHG",
    "output": "Catalyzes the reversible phosphorylation of UMP to UDP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTQKTILNDTHRALGAKMVDFGGWDMPIHYGSQIDEHHQVRRDAGMFDVSHMTVVDLHGVRVREFLRYLLANSVDKLKVSGKALYTCMLNPQGGVIDDLIVYFMQEEFFRLVVNAATRDKDLQWIGEQAARFEVRVKERADFAMIAVQGPNARSKVIDLLDPADASAASKLGRFAALQTRTRDGVALFLARTGYTGEDGFEIVLPQADAVAFWNALLAHGVAPAGLGARDTLRLEAGMNLYGQDMDDNVTPYEAALAWTITLDEGRDFIGRSVLESQKAQGAPRQMIGVVMDEKGVLRHGQKVLSAGGEGEILSGTFSPTLGKAIAFARVPAGSIDDLRVDIRGKQVPLRAVKFPFVRDGQAQPGVLGA",
    "output": "The glycine cleavage system catalyzes the degradation of glycine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPADHIPALALAGPTASGKTAAAFAIADALAPRLPVEIISVDSALVYSGMDIGTAKPTPAEQARVPHHLIDIRDPLQAYSAAEFVQDATRLIGEIRARGALPLLVGGTMLYFKALFDGIDDMPPADAAVRARLEAQAAAIGWSGMHAELARVDPPTAARLAPGDSQRIQRALEVWHVSGRPLSSFHTTKTVAASARPMSAASLFSLEPHDRAWLHGRIAERFHAMLAAGFLDEVLRLRARGDLHADLPSMRCVGYRQAWESLDGLYPMSSLPERGIAATRQLAKRQITWLRSMPERHSIACDAPDATAQLVQAVRARVWGGGA",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTFPVEKVRADFPILQREVNGLPLAYLDSAASAQKPNQVIDAESAFYRHGYAAVHRGIHTLSAQATESMENVRKQASRFINARSAEELVFVRGTTEGINLVANSWGTENIRAGDNIIISEMEHHANIVPWQMLCERKGAELRVIPLHPDGTLRLETLAALFDDRTRLLAITHVSNVLGTENPLPDMIALARQHGAKVLVDGAQAVMHHAVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMISTVSLTQGTTWAKAPWRFEAGTPNTGGIIGLGAAIDYVTSLGLDKIGDYEQMLMRYALEQLAQVPDITLYGPAQRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAWYGVPAMCRASLAMYNTHEEVDRLVAGLTRIHRLLG",
    "output": "Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKIGIIGAMEPEVAHLVESMENPSSTTIAGIEFVAGQLAGKDVVVTRSGIGKVTASIATTLLIEKYAPDAIINTGSAGGFADELAIGDIVISSEVRHHDVDVTAFGYEIGQMAQQPAAFIPDTALVTAAQKAVASLGEVKAIEGLICTGDSFICDPVRTKTMLEHFPTMAACEMEGAAIAQVCHQFDVPFVVIRSLSDNANNDSPVDFDEYLVKAGHHSALMVIALLEQL",
    "output": "Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKRKVKKMAAMATSIIMAIMIILHSIPVLAGRIIYDNETGTHGGYDYELWKDYGNTIMELNDGGTFSCQWSNIGNALFRKGRKFNSDKTYQELGDIVVEYGCDYNPNGNSYLCVYGWTRNPLVEYYIVESWGSWRPPGATPKGTITVDGGTYEIYETTRVNQPSIDGTATFQQYWSVRTSKRTSGTISVTEHFKQWERMGMRMGKMYEVALTVEGYQSSGYANVYKNEIRIGANPTPAPSQSPIRRDAFSIIEAEEYNSTNSSTLQVIGTPNNGRGIGYIENGNTVTYSNIDFGSGATGFSATVATEVNTSIQIRSDSPTGTLLGTLYVSSTGSWNTYQTVSTNISKITGVHDIVLVFSGPVNVDNFIFSRSSPVPAPGDNTRDAYSIIQAEDYDSSYGPNLQIFSLPGGGSAIGYIENGYSTTYNNVNFANGLSSITARVATQISTSIQVRAGGATGTLLGTIYVPSTNSWDSYQNVTANLSNITGVHDITLVFSGPVNVDYFVFTPANVNSGPTSPVGGTRSAFSNIQAEDYDSSYGPNLQIFSLPGGGSAIGYIENGYSTTYKNIDFGDGATSVTARVATQNATTIQVRLGSPSGTLLGTIYVGSTGSFDTYRDVSATISNTAGVKDIVLVFSGPVNVDWFVFSKSGT",
    "output": "Endoxylanase that degrades arabinoxylan and glucuronoxylan to xylobiose and xylotriose (in vitro)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAAITAGLVKELRDKTGAGMMDCKAALTENNGDIEAAIDWLRKKGLAKAAKKAGRVAAEGLVAVESSGHYAAAIEVNAETDFVARNADFQAFVREAAKVALNTDGSIEAVAAAHFPGESVTVADKLATLIATIGENMTLRRSVRLTVSAGVIATYVHGAVSEGQGRIGVLVALESQGDVEKLSTLGRQIAMHVAALNPLALDASGIDEATIAREKAILLEKHQGKPANVQEKIAESGMKTYFKEVTLLEQPFVHDGSKSVAQVLKENEGSVGAPITLKGFVRYALGEGIEKEESDFAAEVAAAAGQS",
    "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPITRAEKEAIIQELKEKFKEARVAVLADYRGLNVAEATRLRRRLREAGCEFKVAKNTLTGLAARQAGLEGLDPYLEGPIAIAFGVDPVAPAKVLSDFIRETRKMEIKAGVLEGTIIDARRVRDLADLPPREVLLARVLGGMQAPLYGFAGALQGTLRKFIYALEAIRKQKAGEA",
    "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAPKGSQRVVKKIVAENRKARFNYEIIDTYEAGIVLMGTEVKSLREGKANIAESYASDEDGEIWLINSYLPEYLQANRFNHEPRRRRKLLLSGREIGRLRSGINREGMTLIPLKIYFNDNGRAKLELALAKGKKLHDKRQSEKERDWNRQKGRILKDNR",
    "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA",
    "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKFKLSLVQFLVSPVKSDNLNRACKLIKEAAQKGAQIVALPECFNSPYGTTYFPEYAEKIPGESTELLSQVAKECGIYLIGGSIPEEDCGKLYNTCAVFGPDGTLLVKHRKIHLFDIDVPGKIRFQESETLSPGDSFSVFDTPYCKVGVGICYDIRFAELAQIYANKGCQLLVYPGAFNMTTGPAHWELLQRARALDNQVYVATASPARDEKASYVAWGHSTIVSPWGEVVAKAGSEETVLSAEIDLQYLAEIREQIPIRRQRRRDLYNVEEKRN",
    "output": "Has omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MMKRKILAAVIPALLAAATANAAEIYNKDGNKLDLYGKAVGRHVWTTTGDSKNADQTYAQIGFKGETQINTDLTGFGQWEYRTKADRAEGEQQNSNLVRLAFAGLKYAEVGSIDYGRNYGIVYDVESYTDMAPYFSGETWGGAYTDNYMTSRAGGLLTYRNSDFFGLVDGLSFGIQYQGKNQDNHSINSQNGDGVGYTMAYEFDGFGVTAAYSNSKRTNDQQDRDGNGDRAESWAVGAKYDANNVYLAAVYAETRNMSIVENTVTDTVEMANKTQNLEVVAQYQFDFGLRPAISYVQSKGKQLNGADGSADLAKYIQAGATYYFNKNMNVWVDYRFNLLDENDYSSSYVGTDDQAAVGITYQF",
    "output": "Forms pores that allow passive diffusion of small molecules across the outer membrane."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAASAVSVLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEIACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE",
    "output": "Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSARIVVSGTDTGVGKTVFSAALAGALDGYYWKPVQSGLDEETDSQTVMRLSGLGAERVWPEAYRLRTPVSPHLAAELDGVTIDHRALEAPHTDRPLVIEGAGGLLVPLTRDVTYLDLMARWRLPVVLCARTALGTINHSLLSIEALRARDVAILGVSFIGEENVETEGIIIDMGRVKRLGRLSYVTPLTRATLRQAFADGFDIGDFVKERAR",
    "output": "Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSFGTLYTHNPTPRSTTLIALAKLHNLDVKIIHAEKKNKEAFEELCRYNPLGQVPTFVGADGFVLSECIPLTLYCNDERSSLRILQWMSFANSDLFPAVGGVFLPRIGQRQIIQQDDGDSLRAMLQRCKYLDEHLKRSRYLVGESITIADFFAASLLMGAFAAFRRSMQERFGALCSWYDGVLEIGWFKKVAGGVPDLGLELEIPEDIKW",
    "output": "Glutathione S-transferase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative . The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG . The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG . The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone . The next step is performed by the anthrone oxygenase mdpH that catalyzes the oxidation of emodinanthrone to emodin (By similarity). Emodin is further modified to yield monodictyphenone via several steps involving mdpB, mdpC mdpJ, mdpK and mdpL . These enzymes with xptA, xptB and xptC are also proposed to be involved in the synthesis of shamixanthone from emodin . Especially, direct reduction of emodin by the short chain dehydrogenase mdpC followed by dehydration catalyzed by the scytalone dehydratase-like protein mdpB gives loss of oxygen and formation of chrysophanol intermediate in two simple steps ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIKLAIDGMGGDNAPKEIVEGSILALKQFDDIELTIFGDVDKMKPYLIEHPRLKVVHTPKYFEMGVKDIGRHTLRDDKDTSMLMAINHVKEGLADGVVSSGPTQALIFASFFMIRPMKEMKRVAIAPMVPTVIGKPTILLDAGGNIDAKAEHLLDFAIFSTIALKEVYGVKSPKVGLINIGTEPGKGRDIDKETFELLSKHPLIDFYGNLEPKEILTSDAQILLSDGFTANIVMKTMEGTASALGKILKREIKASFWGKLAAVLFLKKPLKRFKQSMSADEVGGALIAGLDKVVVKAHGSSEAYAFMNAIRQAKTMVSHDVIGKVKNVLRGQDE",
    "output": "Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MWRVCARRARSAVPRDGFRARWAALKEGPGAPCGSPRIGPAAVRCGSGIPRYGVRSLCGWSSGSGTVPRNRLLRQLLGSPSRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNYTLDLAAAAAPQAAPAAAPAPAAAPAAPSASAPGSSYPTHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGAPLCIIVEKQEDIAAFADYRPTEVTSLKPQAAPPAPPPVAAVPPTPQPVAPTPSAAPAGPKGRVFVSPLAKKLAAEKGIDLTQVKGTGPEGRIIKKDIDSFVPSKAAPAAAAAMAPPGPRVAPAPAGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSVDVNMGEVLLVRKELNKMLEGKGKISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGLETIASDVVSLASKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLIPADNEKGFDVASVMSVTLSCDHRVVDGAVGAQWLAEFKKYLEKPITMLL",
    "output": "The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPLLSQMQDQSGTTFAQLEALRQKLREYEYYYHVLDNPLVPDAEYDRLMNELKNLEWQHPEWITADSPTQRVGAKPLDGFAQVTHEIPMLSLDNAFSDEELDGFLRRMESYITEDPHTLAFCCEPKLDGLAVSILYVDGVLSQAATRGDGTTGEDITSNIRTVRNIPLKLNMDNPPARLEVRGEVFMPQKGFETLNERALEKGEKTFANPRNAAAGSLRQLDPKITRQRPLVLNAYGIGVYESDDELPATHFERLQWLKSIGIPVNNEIRLATGREQLLAFYADIQAKRPTLGYDIDGTVLKVNDIGLQEQLGFISRSPRWAIAYKFPAQEEMTVLNDVEFQVGRTGAITPVAKLEPVFVAGVTVSNATLHNGDEIERLGIVIGDTVIIRRAGDVIPQIVGVVMERRPENAKKIEFPTACPVCESAVVRVEGEAVARCTGGLFCGAQRKEALKHFVSRKAMDIDGVGEKLIEQLMERELVHTPADLFKLEHTTLMRLERMGGKSAQNALNSIEKAKNTTLARFLFALGIRDVGEATAQNLANHFHNLDAIRAATFEQLQEVQDVGEVVANRIVRFWQEPHNVTVVEDLISQGIHWQDVVQVEIADNPLKGKSVVLTGTLTQLTRDQAKALLQSFGCKVSGSVSSKTDYLIAGEKAGSKLAKAQELGVKVLTEQEFIALTGEN",
    "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTMITIDYIKDIIKRSDKLSEEIDPDQTPYKSKYEAIELLVKELKKEINENEKELNQQQQQDILDYLVVIDSKLGELFIATEEITLGLNICRDCLKSLESIKNKFPLETISTFQSIAIIDINKNHFENGKQLLIKSENLINQTIEKQQEQEQEQEQQFKDKLESLQLQNYFYFAQLYGLLKDSELSSKYCELTLRKQLKRNNFDRLEWCKNSLMLAEYYLSELNFDYAKQCFLVSNYICKGIENEDDREETQANIYLVMAKFYLEFLHFFRDIENLNHCHRVNNNNKNNNNENDIDFVQGGLSSISLSDKQKEKEKEDKLFNENQIKKEKMLDLISFNKRSLNIDKPLFTELGSELLDKIYNHSTFTSPIDLIVVKDQPSARDIFLKSQHFFNKSKKYYKLDGFVSQHIKILFDQINLFEYLNMFESNAGRKIGIHKKKIELIQPLLKELNPTYFLSSIRSIYFKIAEIYSEISKIYQCVCTNLREIQTYNECLFKSMEYYNLFLNSYNDGEVPNSPKITEEEKMKSIIEDFEVYINAKLELAVCHKNVKGVNKLVLEHLEKSLNLFRSIITLLDSVPKDISSRHTQEYHLCSQMSSLLPQKIQFLSSNKTPNPGQWYGK",
    "output": "Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPIDQEKLAKLQKLSANNKVGGTRRKLNKKAGSSAGANKDDTKLQSQLAKLHAVTIDNVAEANFFKDDGKVMHFNKVGVQVAAQHNTSVFYGLPQEKNLQDLFPGIISQLGPEAIQALSQLAAQMEKHEAKAPADAEKKDEAIPELVEGQTFDADVE",
    "output": "Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum EGD1 may act as a transcription factor that exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II. Can enhance DNA binding of the GAL4 protein activator."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSDIRLDSATFFKRAAKIFDSWEKPSGDTQALEDINSIAIILGDPNDEVASYTKTTALQLWLLGYEFPSTLMVFEKSPRKVTFVCGSSKAKLIRQLQPSDGIEIDVKVRSKDATAAKETMEEVVASLNGKFGSLPKDRPIGKLVDEWNSAVESKGDLEVVDVAIPISAVLAEKDGEELKTIITSAKLTSTVMINYFKSKMESIIDRGTKMSHEALAQLVEEKIGNEEKGPDMKLWNKNPSLGEIDFASSEFVYSPVIQSGGKYDLKVTAASNNDNLKPGIILANMGIRYKNYCSNMGRTFLISPSKKQETQYTTLLEVRKEALALLKTGAVASDVYNSVHQSLETKNATLADSFLKNLGFATGMEYRDSSFLLNAKNNRELKENMVLVLTIGVADLPDAKNKGKTYSLLLSDTVKIGQNGAVVLTEGCTRLSDVVMDMEEEEEEDVKPQIDKKPKINNSPKKPRSSTVGGRVLNAKTRGANREQATQTTAEKIKTNQQRLHAQLNADGVKRWEADAGGKNGAQQKVVKRYESYRREEQLPRAVEDRRIYVDEQRQSVVLPINGYAVPYHISTIKNVTKTEESNHMVLRINFQSPGQIAGKKEDMPFEDPDANFIRSVSFRSQDQRHMLKVYEAITALKKAAVKRETERKELADVIEQEKLIEVKGRHPYVLKNVFPRPGPEGKKTDGNVEIHQNGIRFRPDGPASKIDILFSNIKHLFFQPSEKELIVIIHVHLKAPIMLGKKKTSDVQFYREVADMSFDETGGKKRRARYGDEDEIEQEQEDRKRRAELDKLFHDFARRIETAAQAQQFELEVDVPFRELGFNGVPHKSIVALLPTTNCLIHISELPFTVITLSEVEIVHLERVQFGLKNFDMVFVLQDLKKPPVHINSIPVAHLDNVKEWLDSCDVPISEGPVNLSWPAIMKTVNEDPHAFYAEGGWNFLTGSGSDDGSEESEEGSEFEGDSDVFDESSGSDEDSESAFEGDSDSASAESLSDEGEDWDELERKAKRADEKHRTDRGGDSDDDGKKKKKGSRR",
    "output": "Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVHHGQMHAQPGVGLRPDTPVASGQLPSTSIRSRRSGISKAQRETWERLWPELGLLALPQSPRGTPVDTRAWFGRDAPVVLEIGSGSGTSTLAMAKAEPHVDVIAVDVYRRGLAQLLCAIDKVGSDGINIRLILGNAVDVLQHLIAPDSLCGVRVFFPDPWPKARHHKRRLLQPATMALIADRLVPSGVLHAATDHPGYAEHIAAAGDAEPRLVRVDPDTELLPISVVRPATKYERKAQLGGGAVIELLWKKHGCSERDLKIR",
    "output": "Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWNCGYLLASSFVFLNLLGQLTGCILVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRNLALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFFSILQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFFQTMSVIGGLLLVVALGPGGVSMDEKKKEW",
    "output": "Endoplasmic reticulum cargo receptor that mediates the export of lipoproteins by recruiting cargos into COPII vesicles to facilitate their secretion. Acts as a cargo receptor for lipoproteins bearing both APOB and APOA1, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis. Synergizes with the GTPase SAR1B to mediate transport of circulating lipoproteins. Promotes the secretion of PCSK9. Also mediates the efficient secretion of erythropoietin (EPO). May also play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAISWAAATTSKLAYPPHVHFSPSPSSNYLFLKTHKPSATHLSSSFIHPTTILHLAAANTTTRRRSFTVRAARGKFERKKPHVNIGTIGHVDHGKTTLTAALTMALASLGNSAPKKYDEIDAAPEERARGITINTATVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSGADGPMPQTKEHILLAKQVGVPNIVVFLNKQDQVDDEELLQLVELEVRELLSKYEFPGDDVPIISGSALLSLEALMANPSIKRGENQWVDKIYELMEAVDDYIPIPQRQTELPFLLAIEDVFTITGRGTVATGRVERGTIRVGETVDIVGVKDTRNTTVTGVEMFQKILDEALAGDNVGLLLRGIQKTDIQRGMVLAKPGTITPHTKFSAIVYVLKKEEGGRHSPFFSGYRPQFYMRTTDVTGKVTEIMNDKDEESKMVMPGDRVKLVVELIVPVACEQGMRFAIREGGKTVGAGVIQSIIE",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTTLACRKLAPHPESPRHQHAGPWLVWLHGLLGSGQDWLPVAQLCGDYPSLLIDLPGHGQSVSLSADGFADISRQLSQTLQANGIREYWLAGYSLGGRIAIYHACYGRHHGLQGLLVEGGNLGLENAELRQARLQQDRQWAQRFRQEPLPQVLDDWYQQAVFADLDPQQREQLVLLRADNHGPAVAEMLEATSLGHQPWLLPALQRLNVPYTYLCGDRDHKFLQLAQQYRLPLHTLARAGHNAHRANPGAFAAQVLAFLSQSSCLPPSSLSR",
    "output": "Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAHQAHAYHMVDPSPWPLTGAIGALFLTSGLAIWFHFQSVTLLTLGLILLLLTMYQWWRDIIREGTFQGHHTPPVQKGLRYGMILFITSEVFFFLGFFWAFYHSSLAPTPELGGCWPPTGITPLDPFEVPLLNTAVLLASGVTVTWAHHSLMEGARKQAIQALALTIILGVYFTALQAMEYYEAPFTIADGVYGSTFFVATGFHGLHVIIGSSFLAVCLLRQIQYHFTSEHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS",
    "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKNVNPTHTLAWKALEDHFAVMKDTEMKTLFSQDPSRFNTFSRTFSDQILVDFSKNRITQETLDKLQALAKECDVAGAIKSMFSGEKINCTEDRAVLHTALRNRSNTPVMVDGKDVMPEVNAVLHKMKVFSERVISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLTMHFVSNVDGTHIAETLKKCDPETTLFLIASKTFTTQETMTNAHSARDWFLSAAKESAFVAKHFVALSTNSAEVEKFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGYDNFEQLLSGAHAMDNHFRTTEAENNIPMILALIGIWYNNFFGTETEAILPYDQYMHRFAAYFQQGNMESNGKYIDRDGNKVSYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAISHNPLSDHHAKLMSNFFAQTEALAFGKTREQVDAEFASAGKDPATMGYVAPFKVFEGNRPTNSILLKEITPYSLGALIAMYEHKIFVQGVIFNIFTFDQWGVELGKQLANRILPELKGKESVNSHDSSTNNLINRYKAWR",
    "output": "Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFPDPNVKYVFRTENGGQVMYRVIQVSEGQLDGQTEGTGAISGYPATQSMTQAVIQGAFTSDDAVDTEGTAAETHYTYFPSTAVGDGAGGTTSGSTAAVVTTQGSEALLGQATPPGTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKNDSN",
    "output": "Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSSVIQVNLPQTSYNIIISPNSLGSVGRHLTSLNLEQKILVISNPEIFDYYGEIVINSLKQAGFKVFSHVIPAGETYKTLDSISKIYDTALKHRLERASTLLALGGGVIGDMTGFAAATWLRGINFIQVPTSLLAMVDASIGGKTGVNHPQGKNLIGAFYQPRLVLIDPIVLKTLPVREFRAGMAEVIKYGVIWNQGLFNQLERQKKLDSLDSINLETIQTIITQSCQAKVDVVSQDEKEAGLRAILNYGHTIGHALESLTGYREINHGEAVALGMVAAGKIAVKLGMWKEEMSQRQKNIIQKAALPVIVDYPLKSQAILESLQLDKKVKAGKVRFILPTDIGQVEIREGVPSEVITRVLEEIKM",
    "output": "Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRQAWRWFGPEAGVPLDAVRQAGATDIVSALHEVPIGQEWTSAQIVERKNLIESTPTGRHPLTWSVVESIPVSDDIKRSGKAARHDIGAWIASMEALARNDIKVICYNFMPVVDWCRTDLDYITSTGATAMRFDQDRFAAFDLHILQRKGAEKDYSEEDRIAARAIFEAMDETEIEQLIVNIASALPGSTTEPLTIPAFREKLETYASIDAAHLRRNLVEFLEAVTPVADSLGVKLTLHPDDPPRSLFGLPRIASTEADYAAIFAAVPAQSNGMCFCTGSLGVRADNDLPAIARRFASRIHFSHLRATTREGDGRTFHEAAHLEGDVDMVGILRILLEEDRKRDAGQTIIFRSDHGHRMMDDLEKKVTPGYPVIGRMRGLAELRGIITALDACALEYDPNV",
    "output": "Catalyzes the dehydration of D-mannonate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKEIKHFISGELVGSASGKLFDNVSPANGQVIGRVHEAGRAEVDAAVRAARAALKGPWGKMTVAERAEILHRVADGITARFGEFLEARMPGHRQAEVAGQPHRHSARRANFKVFADLLKNVANEAFEMATPDGAGALNYGVRRPKGVIGVISPWNLPLLLMTWKVGPALACGNCVVVKPSEETPLTATLLGEVMQAAGVPAGVYNVVHGFGGDSAGAFLTEHPDVDAYTFTGETGTGETIMRAAAKGVRQVSLELGGKNAGIVFADCDMDKAIEGTLRSAFANCGQVCLGTERVYVERPIFDAFVARLKAGAEALKIGEPNDPEANFGPLISHKPREKVPSYYQQAVDDGATVVTGGGVPEMPAHLAGGAWVQPTIWTGLADDSAVVTEEIFGPCCHIRPFDSEEEAIELANSLPYGLASAIWTENVRRAHRVAGQIEAGIVWVNSWFLRDLRTAFGGSKQSGIGREGGVHSLEFYTELKNICVKL",
    "output": "2-hydroxymuconic acid semialdehyde can be converted to 2-hydroxypent-2,4-dienoate either directly by the action of 2-hydroxymuconic semialdehyde hydrolase (HMSH) or by the action of three sequential enzymes, the first of which is HMSD. Can oxidize not only 2-hydroxymuconic semialdehyde and its analogs but also benzaldehyde and its analogs."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKQLSFSNESRDALEKGVNFVANAVKVTIGPKAKNVVIERKFGSPDVVRDGSTVAKEIEIENPISNLGAKLIEQVASKTKESAGDGTTTATILTQKMVQEGLKNIASGASPMELKKGMEVGLAFVLEKLSSKSISLSGSDIQKVATVSAGGDQEIGSIISKAMDIVTSDGVITVEESQSLDTELDITEGMSFDRGYSSPYFVTDQERQVCELENPKILITDQKISTLANLVPILEEIQKSGSPFLILAEDIEGEALTTLVLNKNSGVLNVASVRAPLFGERRKAALEDIAILTGAKLISEDKSMTLDQVSINDLGKAKKITITKDKTTIVAFEDTKDLVKARVEKLKREVEMTESEYDQDKINERIAKLAGGVALIKVGAATETEMKYKKLRIEDSLNATKAAIEEGVVSGGGQTLIEISDELLNLSQKSSDDLRTGINIVKEALLEPTKQIAKNAGFNGDVVVAEIKRLNKGFNANSGKYENLKESGILDPTKVIRLALQDSVSIAAMLLTTEVAIADIPEPEAAAPGGPGGDPMGGMGGMGGMGMPGMGGMGMPGMGGMGMPGMGGMGMPGMGGMGMPGMM",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPSFHNTITIGHRPNGDSKRTTYLVTGASRGIGKGLVASFLARPDSTVIACVRNVASQSKALSDLPCAEGSSLIVVKLDCAVETDPASAVEELQSAHNIRHIDVVVANAAIAGAYGPTSTLPLDAVKEHMQINCYSVLLLFQATRPLLEQAAPGKAKFVFIGAPISTITQMEECARAPLGAYGLTKLAANYLVRKFHFENKWLMSFVIDPGHVQTDMGDSGARLMGRKEAPTTLQQSVDGICARIDEATKEESSGQFLLHEDGSRLPW",
    "output": "Norsolorinic acid ketoreductase; part of the fragmented gene cluster that mediates the biosynthesis of dothistromin (DOTH), a polyketide toxin very similar in structure to the aflatoxin precursor, versicolorin B . The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits hexA and hexB, as well as the polyketide synthase pksA . PksA combines a hexanoyl starter unit and 7 malonyl-CoA extender units to synthesize the precursor NOR (By similarity). The hexanoyl starter unit is provided to the acyl-carrier protein (ACP) domain by the fungal fatty acid synthase hexA/hexB (By similarity). The second step is the conversion of NOR to averantin (AVN) and requires the norsolorinic acid ketoreductase nor1, which catalyzes the dehydration of norsolorinic acid to form (1'S)-averantin . The cytochrome P450 monooxygenase avnA then catalyzes the hydroxylation of AVN to 5'hydroxyaverantin (HAVN) . The next step is performed by adhA that transforms HAVN to averufin (AVF) . Averufin might then be converted to hydroxyversicolorone by cypX and avfA . Hydroxyversicolorone is further converted versiconal hemiacetal acetate (VHA) by moxY . VHA is then the substrate for the versiconal hemiacetal acetate esterase est1 to yield versiconal (VAL) . Versicolorin B synthase vbsA then converts VAL to versicolorin B (VERB) by closing the bisfuran ring . Then, the activity of the versicolorin B desaturase verB leads to versicolorin A (VERA) . DotB, a predicted chloroperoxidase, may perform epoxidation of the A-ring of VERA . Alternatively, a cytochrome P450, such as cypX or avnA could catalyze this step . It is also possible that another, uncharacterized, cytochrome P450 enzyme is responsible for this step . Opening of the epoxide could potentially be achieved by the epoxide hydrolase epoA . However, epoA seems not to be required for DOTH biosynthesis, but other epoxide hydrolases may have the ability to complement this hydrolysis . Alternatively, opening of the epoxide ring could be achieved non-enzymatically . The next step is the deoxygenation of ring A to yield the 5,8-dihydroxyanthraquinone which is most likely catalyzed by the NADPH dehydrogenase encoded by ver1 . The last stages of DOTH biosynthesis are proposed to involve hydroxylation of the bisfuran . OrdB and norB might have oxidative roles here . An alternative possibility is that cytochrome P450 monoogenases such as avnA and cypX might perform these steps in addition to previously proposed steps ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIFKVFYQEKMTEVPVRENTKVLYLEATSEKDVRTKLNKFAYNIEFVQSVTGNHLEYEKANADLTLAEIV",
    "output": "A non-essential component of RNA polymerase (RNAP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAAASTTSRTNSRVNYSNEIHDLSTVQSGSVVPTLFYPDKSIADIFPPHLGKKVISEVVATFLLVFVTCGAASIYGEDNRRISQLGQSVAGGLIVTVMIYATGHISGAHMNPAVTLSFACFRHFPWIQVPFYWAAQFTGAMCAAFVLKAVLHPIAVIGTTTPSGPHWHALLIEIVVTFNMMFVTCAVATDSRAVGELAGLAVGSAVCITSIFAGPVSGGSMNPARTLAPAVASNVFTGLWIYFLGPVIGTLSGAWVYTYIRFEEAPAAKDTQRLSSFKLRRMQSQLAADEFDTV",
    "output": "Aquaporins facilitate the transport of water and small neutral solutes across cell membranes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEVLIRTSLIVREDAQLLYGFSSEEEKDMFLSLIKVTGIGPKSALAILATSTPNEVKRAIENENDTYLTKFPGIGKKTARQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAMLALEALGYSKRELAKVEKTLNKNKYDSVDEAVKAGLQLVVS",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGKRILVQRRGRGGSQFRSPSWKRDGPVRYPPNISGRGIVVEILHEPGLNAPVAKIRMENGVEFFNYAAEGLYVGQVIQVGPDAPPAVGNVLPLGKIPEGTMVFNVEKRFGDGGKFARSGGTYALVIGQRPEENKTIVRLPSGRVIEVDARGRATIGIVAGGGRVEKPFVKAGKKYHRARAKSWKYPTVRGKAMSPYAHPHGGGSHQKGGTPVPKTAPPGQKVGFIGSRCTGRGCVRARAQQKQ",
    "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINCLVITAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQGLCDLWLSVDIICCTCSILHLSAIALDRYRAITDAVEYARKRTPRHAGITITTVWVISVFISVPPLFWRHQGNSRDDQCIIKHDHIVSTIYSTFGAFYIPLVLILILYYKIYRAARTLYHKRQASRMIKEELNGQVLLESGEKSIKLVSTSYMLEKSLSDPSTDFDRIHSTVKSPRSELKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNICEKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRN",
    "output": "G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSKFVFVTGGVVSSIGKGIVAASLGRLLKSRGYSVSILKLDPYLNVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDTAMTRLNSVTTGSIYQAVINKERRGSYNGGTVQVIPHITGEIRERIHRVAANSNADIIITEIGGTVGDIESLPFLEAIREFKNDVNRNDVAYIHVTLLPYIKTSGEIKTKPTQHSVKELRSIGIQPDLLVCRSDKSINEALKKKLSGFCGVSINSVIEALDADSIYSVPLSLKKEGLCKETLNYLELEDKKCDLKNWEQLIHNLRNPGGPIKVALVGKYIELGDAYLSVVEALRHACIEQKALLDLHWVSAEMIEKNSAETYLNEVDAIVVPGGFGNRGVNGKIAAIKFARENKIPFLGLCLGMQCAVIEWARNVAHLPDASSSELDPNTPNPVIHLLPEQQDVVDLGGTMRLGVYPCRLTKNTTGKNLYDEDVIYERHRHRYEFNNYYKQSFLDSGYKISGTSPDGRLVELIELENHPYFLACQYHPEFLSRPGKPHPLFKGLIKASQDKLTQSN",
    "output": "Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPVKKKRKSPGVAAAVAEDGGLKKCKISSYCRSQPPARLISGEEHFSSKKCLAWFYEYAGPDEVVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQNKFDFLRSQLNDISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLLGRTWPLFSVFYQYPEQSKYRVMNKDQWYNVLEFSRAVHADLSNYDEDGAWPVLLDEFVEWQKVRQTS",
    "output": "Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKKRKQYCGYIAIVGKPNVGKSTLINEIIENEISITSKKKNTTQKNILGIKTKQLHQFIYVDTPGIYLNNEKDDSFKIIKSSILILFIVDRTVWKTDDEIVLNKIKKNKIPIICVINKIDKILDKSIILPHINFLLKKINPIEIIPISAKKRENIVLLENLIYPYLPNNNHIFPKKYITTHSLSFSISEIIRQKLIFFLRDELPSIITVKIESIEEKFKKKLYIRAAIYVKHERQKKIIIGKKAEGIKKISIASRLDIEKKINMKIYLIIWVKVKIKK",
    "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MYEAVHAHPDGDATVARHAATAERYGYEGIVVRTREALDPASKSSEHADEATALRDEYGIDVVDAVEIDADNATSASGAVGNYRSDRTVVCVVGGDDGLNRFAVEEPRVDVLVRPMGGGDFNHVLAKAARDNGVHVEFDLGPLFRATGGKRVRALADLRKLREIVTYYDTPHVVSANPRSHLDLRAPREVVAAAEAVGFDAEWVREGLRAWGEIATRNRERRSEAFIEPGVRRGRYEEDG",
    "output": "Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMDPNSTSEDVKFTPDPYQVPFVQAFDQATRVYQDLGGPSQAPLPCVLWPVLPEPLPQGQLTAYHVSTAPTGSWFSAPQPAPENAYQAYAAPQLFPVSDITQNQQTNQAGGEAPQPGDNSTVQTAAAVVFACPGANQGQQLADIGVPQPAPVAAPARRTRKPQQPESLEECDSELEIKRYKNRVASRKCRAKFKQLLQHYREVAAAKSSENDRLRLLLKQMCPSLDVDSIIPRTPDVLHEDLLNF",
    "output": "Transcription factor that acts as a molecular switch to induce the transition from the latent to the lytic or productive phase of the virus cycle  (Probable). Mediates the switch from the latent to the lytic cycle of infection in cells containing a highly methylated viral genome . Probably binds to silenced chromatin and recruits host chromatin-remodeling enzymes . Regulates this switch by binding to 2 types of ZEBRA response elements (ZREs): the CpG-free AP-1 like elements (latency) and the methylated CpG-containing elements (lytic replication)  (Probable). Activates preferentially the methylated forms of the viral lytic R (BRLF1) and Na (BRRF1) gene promoters, the latters being the first genes activated during Z-mediated reactivation in latently infected cells . BZLF1 and BRLF1 act together to trigger lytic replication . Also binds the lytic origin of replication, oriLyt . Induces G1 cell cycle arrest by stabilizing the host CCAAT/enhancer binding protein CEBPA . This function is important because the lytic cycle preferentially takes place in host cells arrested in G1 ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQQTCIRLVKLDMLSTLTRFRTHSAIRCCAQRLFHCRPSLFISARTYFIKIDSSSLPKLKGSVSFSASCVSLGSSRLGLCSSSFKTGAPAALRAPVVFQRTRGFHTSGRRRALPALPLLWMVLKPLQKIMAIILGRSIRKWWVALPANKKQLFREWSWRRRWHFLGAGTGLLFIASLFFFTHLDESPITGRTRLLVFSRKNFRELAQFNADAFMEEFKDSLIASSDPRHKVVEQVVQILAQRNQDIAEISAVPWTVHVVDSPTMNAFVLPNGEIFVFTGMLNAVTDIHQLTFILGHEMAHALIGHAAEQASLSHVVELLSLVLLTAIWAVCPRDSLAALGHWIQGKLVQFLFDRPFSRKLEAEADQVGLQMAAKACADVRAGPVFWEQMEIFDQLSGQPTMPEWLSTHPSHQNRVRQLDRLIPEALELRARCNCPELPKTDPRVVFNEAVRLVLEGKKEQMLEKEEKNGKTQTGDMFP",
    "output": "Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as opa1 and dele1. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of opa1 at S1 position, leading to opa1 inactivation and negative regulation of mitochondrial fusion (By similarity). Also acts as an activator of the integrated stress response (ISR): in response to mitochondrial stress, mediates cleavage of dele1 to generate the processed form of dele1 (S-DELE1), which translocates to the cytosol and activates eif2ak1/hri to trigger the ISR (By similarity). Required for the stability of the respiratory supercomplexes ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHESEVPRVFVGRDTRISGEMLESALVAGLLSVGIHVYKLGVIATPGVAYLVKSEKASAGVMISASHNPALDNGIKFFGGDGYKLDDERELEIEALLDAAEDTLPRPSAEGLGDLVDYPEGLRKYQQYLVSTGLELEGMHVALDTANGAASTSARQIFADLGAQLTIIGENPDGLNINLNVGSTHPEALQEVVRESGAAIGLAFDGDSDRLIAVDENGELVDGDKIMYIIGKYLSEKGELAQNTIVTTVMSNLGFHKALDREGIQKAVTAVGDRYVVEEMRKNGYNLGGEQSGHVIIMDYNTTGDGQLSAVQLTKVMQETGKKLSELAAEVTIYPQKLVNIRVENSMKDKAMEVPAIKTVIERMEAEMAGNGRILVRPSGTEPLLRVMAEAPTDEEVNYYVDTIANVVRDEIGID",
    "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MALSTIVSQRKQIKRKAPRGFLKRVFKRKKPQLRLEKSGDLLVHLNCLLFVHRLAEESRTNACASKCRVINKEHVLAAAKVILKKSRG",
    "output": "Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPW has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKKKALLPLFLGIMVFLAGCDYSKPEKRSGFFYNTFVDPMKNVLDWLGNNLLNDNYGLAIIILVLVIRIILLPFMLSNYKNSHMMRQKMKVAKPEVEKIQEKVKRARTQEEKMAANQELMQVYKKYDMNPIKSMLGCLPMLIQLPIIMGLYFVLKDQLVDGLFKYPHFLWFDLGRPDIWITIIAGVLYFIQAYVSSKTMPDEQRQMGYMMMVISPIMIIWISLSSASALGLYWSVSAAFLVVQTHFANIYYEKVAKKEVQPFIEAYEREHNGGSNKKGKNTQVVSKKKKK",
    "output": "Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMNHDTESHVKISRTIYRGVSPSTTRLESRVRELEDLLDLERDARVRAERHAADLGFQVDALSERLDEAGGSTTQTQELLKRREMEINKLRKDLENANASLELAETSMRRRHQTALNELALEVENLQKQKGKAEKDKSHLIMEVDNVLGQLDGALKAKQSAESKLEGLDSQLNRLKSLTDDLQRQLTELNNAKSRLTSENFELLHINQDYEAQILNYSKAKSSLESQVDDLKRSLDDEAKNRFNLQAQLTSLQMDYDNLQAKYDEESEEASNLRSQVSKFNADIAALKSKFERELMSKTEEFEEMKRKFTMRITELEDTAERERLKAVSLEKLKTKLTLEIKDLQSEIESLSLENSELIRRAKAAESLASDLQRRVDELTIEVNTLTSQNSQLESENLRLKSLVNDLTDKNNLLERENRQMNDQVKELKSSLRDANRRLTDLEALRSQLEAERDNLASALHDAEEALHDMDQKYQASQAALNHLKSEMEQRLRERDEELESLRKSTTRTIEELTVTITEMEVKYKSELSRLKKRYESNIADLEIQLDTANKANANLMKENKNLSQRVKDLETFLDEERRLREAAENNLQITEHKRLQLANEIEEIRSTLENLERLRKHAETELEEAQSRVSELTIQVNTLTNDKRRLEGDIGVMQADMDDAINAKQASEDRAIRLNNEVLRLADELRQEQGNYKHAEALRKQLEIEIREITVKLEEAEASATREGRRMVQKLQARVRELESEFDGESRRCKDALAQARKFERQYKELQTQAEDDRRMVLELQDLLDKTQMKMKAYKRQLEEMEEVSQITMNKYRKAQQQIEEAEHRADMAERTVTVRRVGPGGRAVSVARELSVTSNRGMRATSMM",
    "output": "Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVLTITAPNEFARDWLESHYSELISETLYDLTGAKLAIRFIIPQSQAEEEIDLPPAKPNAAQDDSNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTKSVAFPRQIAMYLSRELTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKQVEEINDILK",
    "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTQHFIVIGNPIAHSKSPEIHTLFGTQAGLDICYQRQYCPDDAASFTAVIEAFFHGGGVGANVTVPFKQIAYECCAARGGLSEHAKVAGAVNTLLLNKALLAKGVPPVEALFGDNTDGQGLVNHMQRLGWPLNGARVAIIGAGGAARGVVLPLIEAGIETLSIANRTVSKAEILVDELSTASEKINQHTIQTYATADLSGDFDIIINATSIGLSGETLPLTDKLNCQYAYDMMYGRELPFLQHFSIRGAQTSDGYGMLIGQAALSFERWTGRAIDVAQATTALENVST",
    "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPAWPRFMSLRRQYLYKALDKNHQKHPIKHPHTRFLSRLFCALAVLFSYSIYQSFRTDLKQSGSWGCEMSWMSPSYRRLEWTEFISTRYALYLYREQGLDSEDTLSGHPVLFVPGNAGSYQQVRSIASSASKQYYEQVKARERNVVTGKKIDFFTADLKEEFSAFHARTVREQAVFIQHCIKGILQEYTHLPQEKRPTQVTLLAHSMGGVVARLAMDPITSISVDIIVTLSTPHILPPLALERDMDSIYSLIRWRRQHISTHPPLISICGGISDTQIVSDSCALPFFQAGNNSDIAVFTTGIPGVWTAVEHQAIIWCHQIRWRIARMLLDMSSRANTTAKLVTAKEWLLDYQEDETLKEPRSERQHDYSVSSRNMTFIGLHQPSKAFVAQQCNGLERCRTVPSVMSLLPFPNNPSDPFPLPGEGIKPSEVMLVAEISLSSTNTVVKINASQYGQTIAGSREHHLVKGNSWSEFTITMRYRYIRIQLLFCIRPTHTSTFSFYCGTLLTLPRQSWHLSGDISIALMSCTTGVAQKKLLQRTGQICDSVPYGRSCMASRVGYCGSSVSIIRFYQHRSVRTCKGFKLILVGEILPWNSALERIARRRMPICIVLLLLGATIQSQLPDFPMLHTFFLGVNQLEMVPLVGILGVWTFGLLCVVSFHLISTCAIFTTLLIPFKILHVAIWSRNIWTGSAALVSTDNNFYYAIPPVLLVKCASCGGTIQKRHVCLKACRIALIILIMSSFSVGARWTWILSPIANAVLILFVASII",
    "output": "Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHKVLAIETSCDETSVSIVSNIGDTFRIHSNIIASQIEDHSKWGGVVPELAARKHLELLPFVLEKALEQAKIKIEEVDYIASTVAPGLVGCLRVGSITARSLCMLHSKPFLGIHHLEGHLSSILFSENYPKKSFLTLLVSGGHTELIKVDDNRGMQRLGKSFDDAAGEAFDKVGRLLGLGYPGGPAIEKIAKNGDPMKFNLPKCRISDKKGGFLKYDFSFSGLKTAVLRLVERINLAGKTVPIPDIAASFERVVAEVLVERTIKCAEDHRLDNVVVVGGVAANNTLRKMMISEASKKSIKVHLAPLDLCTDNAAMIGAAALFRIKFKDHLSNLKLGVAGRLSIEQANTLYEENPPF",
    "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRPLSELDPEELIRYISESPKRTIAKFYVKTDDPEGLAERLEERLEDAKVFTGVDHVIVIGEHDDVVEVLESEDSVEYYHKELDHRNRAVPLADYSEFEDVRIEPGAIIREKVKLGKGVVVMMGAVINIGAKIGDGTMVDMNAVVGSRAEVGKNVHIGAGAVIAGVLEPPSAKPVVIEDDVVIGANAVILEGVRVGKGAVVAAGAVVTEDVPPSKVVAGVPARVVKDVDKKTEAKTQIVDALRCL",
    "output": "Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPWIQLRIDTDGPNADAISDQLMEEGSLSITFEDGKDNPIYEPTLGETPLWSHTVIVALFEANFDLTPVVERLKLLPCLGDNFSHKVEQVEDKDWEREWMDNFHPIKFGDRLWICPSWREIPDPTAVNVILDPGLAFGTGTHPTTALCLEWLDGLDYSNKDVIDFGCGSGILAVAALKLGAERVTGIDIDYQAIEASKANAERNGVEDKLALYLPEDQPADLLADILVANILAGPLRELAPLIAEKVKPGGLLALSGLLQEQAEEISAFYSEWFNMDEPAHKDDWSRLTGIRK",
    "output": "Methylates ribosomal protein L11."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEQSNRQTAEPAIRSAETVDSTINSFQETDLKVQEKEDVAAAVQTESASIDSNEQGQSVSANTNTQSQAKKLSNNSHQEPMQMVSAANKERAVLETAQNQKNGNMINLTTDKAVYQAGEAVHLNLTLNNTTSLAQNITATAEVYSLENKLKTLQYTKYLLPNESYTTQKGEFVIPANSLANNRGYLLKVNISDSQNNILEQGNRAIAVEDDWRTFPRYAAIGGSQKDNNSVLTKNLPDYYRELEQMKNMNINSYFFYDVYKSATNPFPNVPKFDQSWNWWSHSQVETDAVKALVNRVHQTGAVAMLYNMILAQNANETAVLPDTEYIYNYETGGYGQNGQVMTYSIDDKPLQYYYNPLSKSWQNYISNAMAQAMKNGGFDGWQGDTIGDNRVLSHNQKDSRDIAHSFMLSDVYAEFLNKMKEKLPQYYLTLNDVNGENISKLANSKQDVIYNELWPFGTSALGNRPQESYGDLKARVDQVRQATGKSLIVGAYMEEPKFDDNRVPLNGAARDVLASATYQTDAVLLTTAAIAAAGGYHMSLAALANPNDGGGVGVLETAYYPTQSLKVSKELNRKNYHYQQFITAYENLLRDKVENDSAEPQTFTANGRQLSQDALGINGDQVWTYAKKGNDFRTIQLLNLMGITSDWKNEDGYENNKTPDEQTNLLVTYPLTGVSMAEADRIAKQVYLTSPDDWLQSSMISLATQIKTNENGDPVLYIQVPRLTLWDMIYINETIKPETPKVPEQPQHPARTLEPAIPQTPEAVSPLPVANKQAVDENKNEIVSALTGEENDLQLPTLSKRSLSISQAELPQTGDNNETRSNLLKVIGAGALLIGAAGLLSLIKGRKKD",
    "output": "May play a role in sucrose-independent adherence to the pellicle-coated tooth surface."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGCSVVGNCKSVMLMSRMSWSKLALLISVAMAAAMTDSPPTLICMGILVSVVLNWIVCAVCEEASELILGVSLETTRPSPARVIGEPVFDPRYGYVAPAIYDGKSFDVILPISALSSASTRKETVEMAVENSRLQPLESSQTPKSLVALYSQDLLSGWGSRIKGPDGQEYLLTALHVWETNISHLCKDGKKVPISGCPIVASSADSDLDFVLVSVPKNAWSVLGVGVARLELLKRRTVVTVYGGLDSKTTYCATGVAELENPFRIVTKVTTTGGWSGSPLYHKDAIVGLHLGARPSAGVNRACNVAMAFRVVRKFVTVENSELYPDQSSGPARELDAETYTERLEQGIAFTEYNISGITVKTSDREWTTAEALRVARYKPLGGGKAWGDSDDEDTQETAIRPLNLPAGGLPTGQSALGQLIEYAGYVWRDEGIINSNGMPFRSAGKSSCRFREAVCRAVHRDVRAAETEFPELKELAWPSRGSKAEIGSLLFQAGRFERVEAPANLQLAITNLQAQYPRSRPRSCFRREPWCREDFVAEIEKIAHSGEINLKASPGVPLAEIGVSNQQVIDVAWPLVCEAVVERLHALASVDPRQHDWSPEELVKRGLCDPVRLFVKQEPHSRQKIEQGRFRLISSVSLVDQLVERMLFGPQNTTEIALWHSNPSKPGMGLSKASQVALLWEDLARKHQTHPGAMADISGFDWSVQDWELWADVSMRIELGSFPALMAKAAISRFYCLMNATFQLTNGELLTQELPGLMKSGSYCTSSSNSRIRCLMAELIGSPWCIAMGDDSVEGWVDDAPRKYSALGHLCKEYEACPVLPNGDLKEVSFCSHLISKGRAELETWPKCLFRYLSGPHDVESLEMELSSSRRWGQIVRYLRRIGRVSGNDGEERSSNESPATTKTQGSAAAWGPPQEAWPVDGASLSTFEPSSSGWFHLEGW",
    "output": "[Serine protease]: Responsible for cleavage of polyprotein P2A and replicase polyprotein P2AB.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MHLHLLLILALFRAGCVVAGPSYSLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWSSPKPLCSLVNSSIVVKAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFSPTNYHFLSSLKDAKGLLEANITVNISQKGNVFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMIRKKLSVLFYPWKPTSKSELQQAFSVTSLTDTY",
    "output": "Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSSKNEIWKNEALISALKTIEKNYGKEALVVYNEGDDIDHDVISSGSFLIDQAIGIGGYPKGRVVEIFGPESSGKTTLALHAIAEAQKQGEIAAFIDAEHSLDLNYAKKIGVDINSLLVSQPSYGEEALDILETLVKSNSISLIVVDSVAALVPKTELEGEMSDQSIGLQARMMSKALRKLNGVISKSKTTVIFINQLREKIGIMFGNPETTTGGRALKFFSTLRIEVRKGESLIENGIVVANKVKVKVVKNKVAVPFKQTLITIGYDKGIERINEIIELATLYNILDKSGVWYSYEKEKIGQGKNAVKEWLNKNPDKLSKIEFELKEFIEKS",
    "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKNFVAGAQSGRKIQSGGCAIHCQDCSISQLCIPFTLNEQELDQLDNIIERKKPIQKSQVLFKAGDSLNSIYAIRSGTIKSYTISESGEEQITSFHLPGDLVGFDAITQMQHPSFAQALETAMVCEIPFDILDDLAGKMPKLRQQILRLMSSEIKSDQEMILLLSKMNAEERLAAFIHNLSKRYSARGFSAREFRLTMTRGDIGNYLGLTVETISRLLGRFQKLGVISVQGKYITINDLNGLIELTGTNKTKITLVK",
    "output": "It is involved in the activation of genes necessary for anaerobic respiration."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MALRGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV",
    "output": "Mediates export of organic anions and drugs from the cytoplasm . Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics . Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export . Hydrolyzes ATP with low efficiency . Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation . Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity). Mediates ATP-dependent, GSH-independent cyclic GMP-AMP (cGAMP) export . Thus, by limiting intracellular cGAMP concentrations negatively regulates the cGAS-STING pathway ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTKTFSAKAADVVHEWFVIDATDKVLGRVASEVALRLRGKHKAIYTPHVDTGDFIVIINAAQLRVTGAKSTDKIYYSHSGYPGGISSVNFRDMQAKFPGRALEKAVKGMLPKGPLGYAMIKKLKVYGGAEHPHTAQQPKVLEL",
    "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLLQGTHRIGRMAMLLALADQNESPVLSIPKGWKYCTGKVGSMNSQKVVAAMETAAKSNQVIETDVYRETHALYHAIMEALYGVTRGQIQLADVLRTVGLRFAIVRGTPYDGKKEGEWVAVALYGTIGAPVKGSEHEAIGLGINHI",
    "output": "Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTASQRTLMVMAGGTGGHVFPGLAVAHRMEAAGWRVVWLGNPAGMEATLVPKHGIPMEYVRFGGLRGKGLKTKLTLPVNLLRACWQSLGALRRVRPDVVLGMGGYITFPAGVMTALSGRPLVLHEQNSIAGLTNKVLAKLAKRVLVAFPGALPHAEWTGNPIRAELAHTEPPHARYASRSGPLNVLVVGGSLGAAALNEVVPRALALLAPGERPRVVHQAGVKHIEALKANYEAAGFAAGEDVRLVPFIDDMAAAYAAADLVICRSGAMTVSEIAAVGVAALFVPFPYAVDDHQTTNAAFLAEAGAAVLVQQRDLSAELLADWLRGQSRASLADMAERSRALAKPEATDEVARVCAKAAGANLETLQ",
    "output": "Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMKMMIMSSSNLMNINFMKMNHPMSIMMTIIIQTLFISMMTGTMMESFWLSYILLLTFLGGMMVLFIYITSIASNEMFKIKINSIIIIVYMMIILSTLMYKLDKTISTEMIKNSEIMNLNYSINFKEMSTSLVKLYNNPTVIITIMMMIYLFITLLAVVKITNINQGPMRKMS",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAVFPNSCLAGCLLIFILLQLPKLDSAPFDVIGPQEPILAVVGEDAELPCRLSPNVSAKGMELRWFREKVSPAVFVSREGQEQEGEEMAEYRGRVSLVEDHIAEGSVAVRIQEVKASDDGEYRCFFRQDENYEEAIVHLKVAALGSDPHISMKVQESGEIQLECTSVGWYPEPQVQWRTHRGEEFPSMSESRNPDEEGLFTVRASVIIRDSSMKNVSCCIRNLLLGQEKEVEVSIPASFFPRLTPWMVAVAVILVVLGLLTIGSIFFTWRLYKERSRQRRNEFSSKEKLLEELKWKRATLHAVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKPERFDSWPCVMGREAFTSGRHYWEVEVGDRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYGNGYWALTPLRTPLPLAGPPRRVGVFLDYESGDIFFYNMTDGSHIYTFSKASFSGPLRPFFCLWSCGKKPLTICPVTDGLEGVMVVADAKDISKEIPLSPMGEDSASGDIETLHSKLIPLQPSQGVP",
    "output": "May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVLRQLSRQASVKVGKTWTGTKKRAQRIFIFILELLLEFCRGEDSVDGKNKSTTALPAVKDSVKDS",
    "output": "Alters the structure of the nuclear envelope by interacting with host CBX5 and disrupting CBX5 association with LBR. Involved in the perinuclear-nuclear localization of the capsid protein VP1 during virion assembly and maturation. Plays an important role in the release of progeny virions from infected cells and in viral propagation, probably by acting as a viral ionic channel in the host plasma membrane. Allows influx of extracellular calcium ions in the host cell. May contribute to viral genome transcription and translation of viral late proteins (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKFLDEAKVYIRSGDGGNGCVAFRREKFIEFGGPSGGNGGRGGNVIIEVADGLNTLIDYRYQQHFKAQKGENGAGSDRHGANGKNIVLKVPMGTQIFDEDRETLIHDFTNVGEKFVLAEGGNGGFGNAHFKSSTNRAPRNANPGQPGEERWIWLRLKLIADAGLVGLPNAGKSTFLSKVSAAKPKIADYPFTTLHPQLGVVNADGREFVLADIPGLIEGAHEGAGLGDRFLGHVERCRVLLHLVDATCEHAGKAYKTVRTELDAYGGLLTDKIEIVALNKIDAVEPDELKKQKDRLKRAAKKTPLLLSAATGEGVKEALRALVAVIGEAPVSAKAKSAAEAEPWSA",
    "output": "An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MENLISLVNKIQRACTALGDHGENSALPTLWDSLPAIAVVGGQSSGKSSVLESVVGKDFLPRGSGIVTRRPLVLQLHKIEEGSREYAEFLHLPRKRFTDFVAVRKEIQDETDRETGRTKQISTVPIHLSIYSPNVVNLTLVDLPGLTKVAVEGQPDSIVKDIEDMVRSYIEKPNCIILAISPANQDLATSDAIKISREVDPTGDRTIGVLTKIDLMDKGTDAVDILEGRAYRLKFPWIGVVNRSQQDINKNVDMIAARRREREYFNSTPEYKHLANRMGSEHLAKMLSKHLETVIKSKIPGIQSLINKTIAELEAELTRLGKPVAADAGGKLYAIMEICRSFDQIFKDHLDGVRPGGDKIYNVFDNQLPAALKRLQFDKQLSMENIRKLITEADGYQPHLIAPEQGYRRLIESSLITIRGPAEAAVDAVHSLLKDLVHKAISETLDLKQYPGLRVEVGAAAVDSLERMRDESKRATLQLVDMECGYLTVDFFRKLPQDVDKGGNPTHSIFDRYNDSYLRRIGTTILSYVNMVCATLRNSIPKSIVYCQVREAKRSLLDHFFTELGKMETKRLSSLLNEDPAIMERRSALAKRLELYRSAQAEIDAVAWSK",
    "output": "Microtubule-associated force-producing protein."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSTTDDTHNTLSTGKCPFHQGGHDRSAGAGTASRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYSALKGDLKALLTDSQPWWPADWGSYVGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAAAASHVGADPEAAPIEAQGLGWASSYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPDIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKARYIGPEVPKEDLIWQDPLPQPLYQPTQEDIINLKAAIAASGLSISEMVSVAWASASTFRGGDKRGGANGARLALAPQRDWDVNAVAARVLPVLEEIQKTTNKASLADIIVLAGVVGIEQAAAAAGVSISVPFAPGRVDARQDQTDIEMFSLLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTVLVGGMRVLGTNFDGSQNGVFTDRPGVLSTDFFANLLDMSYEWKPTDESNELFEGRDRLTGEVKYTATRADLVFGSNSVLRALAEVYACSDAHEKFVKDFVAAWVKVMNLDRFDLQ",
    "output": "Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "SVNPCCDPVICKPRDGEHCISGPCCNNCKFLNSGTICQRARGDGNHDYCTGITTDCPRNRYN",
    "output": "May bind to both alpha-IIb/beta-3 (ITGA2B/ITGB3) and alpha-V/beta-3 (ITGAV/ITGB3) integrins, and may inhibit platelet aggregation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPEPAKSAPAPKKGSKKAVTKTQKKGDKKRRKTRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK",
    "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSDISVEKLTELEAAAELERLARAIAHHDELYHAKDRPEISDAAYDALKRRNEAIEAHFPALVRDDSPSRRVGAAPALATFAPVVHARPMLSLDNAFSDEDVRDFVGSVYRFLGQLPDDSIAFTAEPKIDGLSMSIRYENGILVSGATRGDGTTGENVTANIRTIAEIPNRLPAGAPAVVEVRGEVYMAKSDFLTLNAQMEAEGKQTYVNPRNTAAGSLRQLDAKVTASRKLRFFAYAWGEMSDMPADTQLGMVEVFRQWGFPVNPLMKRFNSVDGLLAHYRAIGMERPTLDYDIDGVVYKVDRLDLQTRLGFRSRSPRWAIAHKFPAEQALTILRGIDIQVGRTGALTPVARLEPITVGGVVVTNATLHNEDYIKGIGQKGEPIREGRDIRIGDSVIVQRAGDVIPQIVDVVLEEGKKRGEPYQFPHVCPACGSHAVREEGEAVRRCTGGLICPAQAVERIRHFVSRNAFDIEGLGEKQVEFFFNAEDPALCIRSPADIFTLKKRQENSLTKLQNIEGFGATSVKKLYDAIDARREIALHRFLFGLGIRHVGEVNAKRLARAYLSYAAFEKAALEAVPPKEGDRTDKGSEAWQDMLAVEGIGSIVAEAVVDFYGEPHNREVLAALLAEVTPLDEEARVATGSPVEGKTVVFTGSLERMSRDEAKAMAERHGAKTAGSVSKKTDLVVAGPGAGSKLAKATELGIEVINEDDWFKLVGED",
    "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDQKQIEEIVRSVMASMGQAAPAPSEAKCATTTCTTPVTSESCALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRIATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR",
    "output": "Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKFLFDLFPVILFFITFKIYGIYAATAVAIGATFAQIGWVWFRHGKVDTMLWVSLVLIVVFGSATLILQDETFIKWKPSVLYWLFAAALLIAQAIFKKNFIRTMMKEQLTLPEPVWARVNASWAAFFAFMGAANLYVAFNYSTETWVNFKLFGFMGLMLVFVVLQGLMLSKYMATDEDKEA",
    "output": "Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTYFMFLLLMALVVGLVAVASNPTPYFAALGLVVAAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPEAWGSRSVLGYVLVYLLGVGLVAGFFWGGWYEGSWVVVDGLKEFSVLRGDVSGVAVMYSSGGGMLVICAWVLLLTLLVVLELTRGLSRGALRAV",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKSTSKIYTDKDSNLDVIKGKRIAVLGYGSQGRAWAQNLRDSGLNVVVGLEREGKSWELAKSDGIIPLHTKDAVKDADIIVFLVPDMVQRTLWLESVQPYMKKGADLVFAHGFNIHYKLIEPPKDSDVYMIAPKGPGPTVREYYKAGGGVPALVAIQQDVSGTALQKALAIAKGIGATRAGVIPTTFKEETETDLFGEQVILVGGIMELMKAAFETLVEEGYQPEVAYFETINELKMLVDLVYEKGITGMVKAVSDTAKYGGMTVGKFVINEDVRKRMKEALQRIKSGKFAEEWVEEYGRGMPTVVNGLSQVQNSLEEKIGNQLKDLIQKGKPKKS",
    "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDYQTIPSQGLSGEICVPGDKSISHRAVLLVAIAEGQTQVDGFLMGADNLAMVSALQQMGASIQVIEDENILVVEGVGMTGLQAPPEALDCGNSGTAIRLLSGLLAGQPFNTVLTGDSSLQRRPMKRIIDPLTLMGAKIDSTGNVPPLKIYGNPRLTGIHYQLPMASAQVKSCLLLAGLYARGKTCITEPAPSRDHTERLLKHFHYTLQKDKQSICVSGGGKLKANDISIPGDISSAAFFIVAATITPGSAIRLCRVGVNPTRLGVINLLKMMGADIEVTHYTEKNEEPTADITVRHARLKGIDIPPDQVLLTIDEFPVLLIAAAVAQGKTVLRDAAELRVKETDRIAAMVDGLQKLGIAAESLPDGVIIQGGTLEGGEVNSYDDHRIAMAFAVAGTLAKGPVRIRNCDNVKTSFPNFVELANEVGMNVKGVRGRGGF",
    "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRLILSLPVLVVVLSMVLEGPAPAQAAGEISSTFERIPDKLKEFGNTLEDKARAAIESIKKSDIPAKTRNWFSEAFKKVKEHLKTAFS",
    "output": "Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIVAVIHTEKERESAEPEELIEPFLTRFVGKVQGKNDRLSIVPDHPLLKDAIPCRAARGVQHEFKEGDWAVAEMRRHPLKGDRSFYADLTQYITFADDHFVPWWVTLARHNLEKEAPNGVATEMLDEGLERQDLTALNFVTIDSASTEDMDDALYAEELADGRLQLTVAIADPTAWIAEGSKLDNTAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPALACRMIIAADGTIDDDIAFFAATIESKAKLAYDNVSDWLENNGTWQPDNEGIAQQIRLLHRICLSRSEWRHHHALVFKDRPDYRFVLGEKGEVLDIVAEPRRIANRIVEESMIAANLCAARVLRDKLGFGIYNVHTGFDPANADALAALLKTHGLHVDAEEVLTLEGFCKLRRELDAQPSGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGEAIARPQEDITQQMAERRRLNRMAERDVGDWLYARFLNDKAGTNTRFAAEIIDVSRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPAA",
    "output": "Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQSTTLYLKTAAFLGGCSLFAATALAATSTATRPQLSNADARAYTIASYMASFGTIGSLTTDNWDPTGGVGAVSGFRANYAVAADGSAQYKTVQAAIDAAVADGGVARKYISVKAGTYNELVCVPESAPPITLYSLDANANNTVIVYNNANPTPASGAKTNPCMGTSSNATVGTVRSATAMVRASNFNARNLTFKNSYVEGTFADNNQSAVALAVRGDKAILENVSVIGNQDTLYLGATNNTMVIRAYFKNSFIQGDTDFIFGAGTAVFHGCTIQYTAARLGARATSYVFAPSTAPDNPHGFLAINSTFNATGNASNNSTHLGRAWDQGVSGTSAYINGSSPNGQVVIRDSSLGAHIRLADPWGPSTAGRPYCSSKCAYSANRFFEYNNTGAGSGN",
    "output": "Involved in maceration and soft-rotting of plant tissue."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEFLMSKHEADAPHLLIVEARFYDDLADALLDGAKAALDEAGATYDVVTVPGALEIPATISFALDGADNGGTEYDGFVALGTVIRGETYHFDIVSNESCRALTDLSVEESIAIGNGILTVENEEQAWVRARREDKDKGGFAARAALTMIGLRKKFGA",
    "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDTIWDISPPIAPATPVWPGDTPVGIERVWRIEAGSPVNVARITLSPHTGAHADAPLHYDAHGAPIGAVPLDAYLGRCRVIHCIGAHPVVSPDDVRAALADAPPRVLLRTYGQAPQRAWDSAFCAVAPQTIDLLAAHGVRLVGIDTPSLDPQESKTMDAHRRIRAHGMAILEGLVLDEIAAGDYELIALPLKFATLDASPVRAVLRALPDAPR",
    "output": "Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVAQSYDMIDNAPEEKERGITINTSHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVIAGSALKALEGDAQYEEKILELMEAVDTYIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEVEIIGLHDTSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDVQRGQVLAAPGSITPHTEFKAEVYVLSKDEGGRHTPFFSNYRPQFYFRTTDVTGVVHLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEIIK",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MREEDLDWEEIGLRVGLEIHRQLDTSRKLFCRCTPELVEEVPKEPKVRRKLRPVQSEMGEFDPAALEEFKRDRTFYYLADGSFSCLVELDEEPPHEPCSEALDVAIKVTLLLGGSVVDEVHVMRKMVIDGSNTTGFQRTMLVGFGGEVPTSEGPVRISTVCLEEDAARKVKGRDQDLEVDYCLDRLGIPLIEVSTEPDIRTPEQAREAAERIGEAIKAVGGVKSGIGTVRQDVNVSIEGGAVQEIKGVQDLNLIPKVVKYEALRQANLLRIRDELRERGVSETDLIDCEPMDVTDVFEDTDSEVIRRELERGGVVYALLLPGFEGILGWELCPGRRFGTELADYARRRGVSGLFHSDELPKYGISEEEVEAVRQRLGAEDGDGFVLIAGPEDRVKSAMEAVKDRAIMALKGVPAETRRARKDGTTEYMRPRPGAARMYPETDIPPVVIDEDRVKELAEELPEKPWERKERLAEEYGLGEELVEQMFEHGVVDEFEEIVEETGVEPKVAAATLVNTIPRLEKDGYPVDNLTIDHVKEVLRLYAEGAIAKSGIEELLGALAADPDSDPEELAEELGIVMASEEEIEEVVEEAIRRYEDKIRERGMAVMGKIMGEVMEVLRGRADGKRVSELVRERIREISGE",
    "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLVNEGIRAREVRLVGANGDQIGVKSKHEALEMAQRVNLDLVCVAPNAKPPVCRIMDYGKYRYEQQKKEKEARKNQKVITIKEVRLSPTIEANDFNTKLRNARKFLEKGDKVKASIRFRGRAITHSQIGRDVLERLAKECEDIATIEARPKMEGRSMFLVMAPKTEK",
    "output": "IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPEAVAAAVSPAAAAATAMCAEHREKLEHIERVTRNAGQEQRRVLEEILAQNAQAEYLRRLGVPGDAPGADEAFRRLAPLVTYEDILPDVLRIANGDTSPILSGKPVSEFLTSSGTSGGERKLMPTIEEEMERRSGLYSLLMPVMSRQVPGLDKGKAMYLYFVKSEWRTPGGLPARPVLTSFYRSRYFLERPHDPYTVYTSPDEAVLCEDAYQSMYAQLICGLVHRADVLRVGAVFASGFLRAIRFLEKHWPSLCRDIRAGELDGGVTDPAVRGAVGRVLRGADPALADAIEAECARPSWQGIIRRVWPSTKYIDVIVTGAMAQYIPTLEFYGGGLPLACTMYASSECYFGLNLNPMCKPSEVAYTLIPTMCYFEFLPVNSGANDVAAPEPDHRGLVDLVDVKLGHEYELVVTTYSGLYRYRVGDVLRVAGFKNAAPMFAFVRRKNVALSIDSDKTDEAELHAAVTEAVQHLAPFGASLVEYTSYADTATTIPGHYVLFWELRSPAGGTPVPASVFEDCCLAVEEGLNSVYRQCRAADRSIGPLEIRVVADGTFDKLMDYALSRGASINQYKAPRCVRPGPVVELLDGRVQATYFSPKCPKWCAGGNKQWISSGAAAKKTTTTCDSLAV",
    "output": "May catalyze the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNLHEYQAKQLFARYGMPAPTGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKLVNSKEDIRAFAEQWLGKKLVTYQTDANGQPVHQILVEAATDIDKELYLGAVIDRSSRRVVFMASTEGGVEIEKVAEETPELIHKIALDPLTGPQPYQGRELAFKLGLTGKQVGQFTKIFMGLATLFLERDLAMVEINPLVVTKQGDLICLDGKLGADGNALFRQPELREMRDPSQEDAREAHAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVFVNIFGGIVRCDLIADGIIGAVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAATSLTDAAQQVVAAVGAK",
    "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSRYRGPRVRIIRRLGALPGLTSKTPQLKSSSINQSTSNKKISQYRIRLEEKQKLRFHYGITERQLLNYVRIARKAKGSTGEVLLQLLEMRLDNVIFRLGMAPTIPGARQLVNHRHILVNDYVVDIPSYRCKPQDFITIKNQQKSETIISKNIEFYQKYKIPNHLTYSSLEKKGLINQILDRESIGLKINELLVVEYYSRQA",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLSFHQLKFNIYQKQLFDNLSITFLDSAITYIKGANGCGKTSLLRMIAGIMQPSNGNIFYKNLNINNIAKPYCTYIGHNLGLKLEMTVFENLKFWSEIYNSVETLDAAIHYFKLYDLLDEKCYTLSSGLQKVVALARLIACQSDLWLLDEVETNLSKENRDLLNNLIVMKANSGGIVLLSSHTENHIKSAQILQLT",
    "output": "Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATKTLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSIHLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAGTLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTANGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDRGYVDLHGKLKQLGADIERIND",
    "output": "Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATAQSNSPRVFCIGTADTKFDELRFLSEHVRSSLNSFSNKSSFKVGVTVVDVSTSRKETNSCADFDFVPSKDVLSCYARGEGTVGRFPDIRGQAIAIMNKALETFLSKANGEQNLAGVIGLGGSGGTSLLSSAFRSLPIGIPKVIISTVASGQTESYIGTSDLVLFPSVVDICGINNVSKVVLSNAGAAFAGMVIGRLESSKEHSITNGKFTVGVTMFGVTTPCVNAVKERLVKEGYETLVFHATGVGGRAMEDLVRGGFIQGVLDITTTEVADYVVGGVMACDSSRFDAILEKKIPLVLSVGALDMVNFGPKTTIPPEFQQRKIHQHNEQVSLMHTTVGENKKFAAFIAEKLNKASSSVCVCLPEKGVSALDAPGKDFYDPEATSCLTHELQMLLENNERCQVKVYPYHINDVEFANALVDSFLEMSPKSGHVECQTAESKSIQGIQNVNAVLEKYPSCNGKNFSRLNDFPNAKPETLQKRIVILQKLKDQISKGKPIIGAGAGTGISAKFEEAGGVDLIVLYNSGRFRMAGRGSLAGLLPFADANAIVLEMANEVLPVVKEVAVLAGVCATDPFRRMDNFLKQLESVGFCGVQNFPTVGLFDGNFRQNLEETGMGYGLEVEMIATAHRMGLLTTPYAFCPDEAVAMAEAGADIIVAHMGLTTSGSIGAKTAVSLEESVTCVQAIADATHRINPDAIVLCHGGPISSPEEAAYVLKRTTGVHGFYGASSMERLPVEQAITATVQQYKSISME",
    "output": "Inhibitor of viral RNA replication which confers resistance to some tobamoviruses including tobacco mild green mosaic virus (TMGMV) and pepper mild mottle virus (PMMoV), but not to tomato mosaic virus (ToMV strains L, ToMV0 and ToMV1-2) and tobacco mosaic virus (TMV) . Prevents tobamoviruses RNA replication by affecting the association of tobamoviruses replication proteins (large and small subunits) with host membrane-associated proteins (e.g. TOM1, TOM2A and ARL8), thus inhibiting the replication complex formation on the membranes and avoiding viral negative-strand RNA synthesis ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEIAPWLKNDIIVMISSVMEAAGQVVFDNLPLLFAVGTALGLAGGDGVAALAALVGYLIMNATMGKVLHITIDDIFSYAKGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAWCYNKFYNITLPPFLGFFAGKRFVPIVTSVVAIATGVLLSFAWPPIQDGLNSLSNFLLNKNLTLTTFIFGIIERSLIPFGLHHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLKDGVPFTAGAFTTGKYPFMMFGLPAAAFAIYKNARPERKKVVGGLMLSAGLTAFLTGITEPLEFSFLFVAPVLYGIHVLLAGTSFLVMHLLGVKIGMTFSGGFIDYILYGLLNWDRSHALLVIPVGIVYAIVYYFLFDFAIRKFKLKTPGREDEETEIRNSSVAKLPFDVLDAMGGKENIKHLDACITRLRVEVVDKSKVDVAGIKALGASGVLEVGNNMQAIFGPKSDQIKHDMAKIMSGEITKPSETTVTEEMSDEPVHVEALGTTDIYAPGVGQIIPLSEVPDQVFAGKMMGDGIGFIPEKGEIVAPFDGTVKTIFPTKHAIGLESESGVEVLIHIGIDTVKLNGEGFESLINVDEKVTQAQPLMKVNLAYLKAHAPSIVTPMIITNLENKELVIEDVQDADPGKLIMTVK",
    "output": "The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in alpha- and beta-glucoside transport (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHVLEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLDRVTKICFCGDHDDLTRLQIQLHEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDNPHLPYSPE",
    "output": "Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTDPAKTHTPMMQQYLAIKAEYPDTLVFYRMGDFYEVFFADAEKAARLLDITLTRRGQSGGEPVVMAGVPFHSLEGYLAKLIKLGESVAICEQVGDVATSKGPVERKVVRVVTPGTLTDTELLNDKAESILLAVHQGARNTCGLAWLSVTQGEIHLAHCANDELETWLARVNPSELLYNVDVTPAFEQRLKTQRCAASARPAWQFDGALGARRLLEQLKVASLASWNAEALNEAHAAASALLGYAEHTQGRALPHVQGLQVVRSGELIELPQSTRRNLELTQTLRGEDSPTLFSLLDTCSTGMGSRALKSWLLSPRRDRAQAQARLEAIAHLRSGPQQTLRARLKGCSDVERITARLALRQVRPRELVALRQTLDKLQQQSERAAGESIGLPELLTRIFEDLQPPPGCTELLGRYVLDEPAALIRDGGVINHGCDADLDELRAIQTNCDGFLLELEGRERARTGIANLRVQFNKVHGFYIEVTQGQLDKVPDDYRRRQTLKNAERYITPELKAFEDKALSAQERALAREKWLYEQLLDQLQAFIPALSRLARALASLDALCALAERSLTLNWAAPVFVKEPCIDITQGRHPVVEARLAETGGGSFIANDCSLSGKHRMQVITGPNMGGKSTYMRQVALIVLLASVGSYVPAARCRLGPIDAIHTRIGAADDVANAQSTFMLEMTEAAQILHTATPHSLVLMDEIGRGTSTFDGLALAGGIAAYLHNKTQAFTLFATHYFELTEFPAQHHGAINVHVSAVESGANIVFLHHIEPGPASKSYGIAVAKLAGVPSAVVTHARHALSALETQQTETRAQVDLFAAPPEAAAPVQTALDRALDTIDPDTLSPREALDALYQLKKLSALA",
    "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MANTYKSIAVSIIFLLYFSCVSSQQQTKFLNHGFLEANLLKSGSSKIHPSGHLELTNTSMRQIGQAFHGFPIPFLNPNSSNLVSFPTSFVFAITPGPGAPGHGLAFVISPSLDFSGALPSNYLGLFNTSNNGNSLNCILAVEFDTVQAVELNDIDDNHVGIDLNGVISIESTSAEYFDDREAKNISLRLASGKPIRVWIEYNATETMLNVTLAPLDRPKPKLPLLSRKLNLSGIISEENYVGFSAATGTVTSSHFVLGWSFSIEGKASDFDITKLPSLPDPLPPLSPSPSPPVSVMKNSSNTMLIIIIAASAIFGILILSFLAVCFFRRTENFTGGARKFSHQTISSATGGFDNSKLLGEGNSGSFYKGQLAPTEIIAVKRITCNTRQEKTALIAEIDAISKVKQRNLVDLHGYCSKGNEIYLVYEYVINRSLDRFLFSNDLPVLKWVHRFCIIKGIASALQHLHAEVQKPLIHGNVKASNVLLDGELNARLGDYGHGSRHSTTGHVAPELVNTGKATCATDVFEFGVLIMEIVCGRRAIEPTKEPVEISLVNWVLRGVKSGNLLRRCDKRIKKKNLVSEEVLLVLKTGLLCVRRSPEDRPMMKKVLEYLNGTEHLPHDDYVV",
    "output": "Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTSPKQSDLLILGLETSCDETAASVVRRAADGTVTVLSSVIGTQFEKHAPFGGVVPEIAARAHVESIDAIAAEAVRAAGVGFGDLDGVAATAGPGLVGGVMVGLAFGKAVALARGAPLVAVNHLEGHAVSARLGADIAYPFLLLLVSGGHCQLLEVSGVGACKRLGTTIDDAAGEAFDKIAKSLGLPYPGGPALEKLAVGGDPTRYALPRALLGRKDCDFSFSGLKTAAARIAETLTTDDARRDLAAGVQAAIARQLSERVDRAMKLYKDSHDPEDLRFVVAGGVAANGAVRAALLADCEKNGFSFAAPPLAYCTDNAAMIALAGAERLALGIFDDLDAIARPRWPLDEAAALANPANAYGRKGAKA",
    "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTSVVYHAFSQKEAKELDVQHSGAQRAEAFVRAFLKRSMPRMSQQALEDHLQRKAVVLEYFTHRKQKEKRKKSKGLSAKQRRELRLFDIKPEQQRYSLFLPLHELWKQYIRDLCNGLKPDTQPQMIQAKLLKADLHGAIVSVTKSKCPSYVGVTGILLQETKHVFKIITKEDRLKVIPKLNCVFTVEIDGFISYIYGSKFQLRSSERSAKKFKAKGTIDL",
    "output": "Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPFRSNNPITRDELLSRFFPQFHPVTTFNSGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPASIAPKPHLYLRDWMVVDYLPGAVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRPLRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTEQHRQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQIGDQQFIRLADDTWRQLLIKQ",
    "output": "Catalyzes the phosphorylation of thiamine to thiamine phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALSEALEKLWRRHCRLARGS",
    "output": "RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTILLTGGSGKTAGHIANLLKEAKLPFIVGSRSSNPHTVERHRTFDWLDEATFNNVLSVDEGMEPVSVVWLVSPPILDLAPPVIRFIDFASSRGVKRFVLLSASTVEKGGPAMGLIHAHLDTIEGVSYTVLRPSWFMENFSTRGEFPCDTIREEDTIYSAAKDGKIPFISVADIARVALRALTAPALHNKDHVLLGPELLTYDDVAEILTRVVGRNIHHVRLTESELAAKLQERGMPADEAAMHASLDSIVEAGAEEKLNTEVKDLTGEEPRHFADFVSDNKNVWLMRD",
    "output": "Agroclavine dehydrogenase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid ergovaline, the predominant ergopeptine product in E.festucae var. lolii . DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (By similarity). The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (By similarity). The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by easD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (By similarity). Agroclavine dehydrogenase easG then mediates the conversion of chanoclavine-I aldehyde to agroclavine via a non-enzymatic adduct reaction: the substrate is an iminium intermediate that is formed spontaneously from chanoclavine-I aldehyde in the presence of glutathione (By similarity). Further conversion of agroclavine to paspalic acid is a two-step process involving oxidation of agroclavine to elymoclavine and of elymoclavine to paspalic acid, the second step being performed by the elymoclavine oxidase cloA . However, cloA does not encode a functional enzyme indicating that C.fusiformis terminates its ergot alkaloid pathway at elymoclavine ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTYPARAVVDLGAIAGNVARLREVAGPAEVMAVVKGDAYGHGLVPVARAALGAGATWLGVAQLGEALTLRAAGVDARTLTWLYAPGAPLAEALRADLDLSVAAPWALDEVVGAARESGVVARVHLKVDTGMGRSGLFLDEWGGLLDAAVRAQAAGEIDVVGVWSHLASADDAESGLTAEQTRVFAEAVRRAEDAGAHLEVRHLANSAGTLAHAATHFDLVRPGIAVVGLSPFGDRTADELGLTPAMRLEAELTIVKHAPAGQGVSYGHEYTTSEATSLAVVPLGYADGIPRHAGGAGPVQVGDTWSRIAGRVCMDQFVLDLGAGANAHAGDVAVLFGSGADGEPTAADWARAADTITYEIVTRLGPRVPRVHVGGRDA",
    "output": "Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRVVILGSGVVGVASAYYLARAGHEVTVIDREAGPALETSFANAGQISPGYAAPWAAPGVPLKAVKWMFEKHAPLAIRLDGTRFQLQWMVQMLRNCTAERYAVNKGRMVRLAEYSRDCLQALRADTGIQYEGRTGGTLQLFRTQQQLDGAAKDIAVLQEANVPFELLSPAELKHAEPALAAVSHKLTGGLRLPGDETGDCQLFTTRLAALAESLGVKFRYNTPIDALAIAGGKIAGVQCGSETVRADAYVVALGSYSTNFISNLMKIPVYPLKGYSITAPIVDAAAAPVSTVLDETYKIAITRFDQRIRVGGMAEIVGFDKTLRAARRETLEMCVNDLFPGGGDTSKATFWTGLRPMTPDGTPIVGRTPVSNLFLNTGHGTLGWTMSCGSGQLLADLISGKKPAIQADDLSVHRYLKDAPGQTRPAYA",
    "output": "Oxidative deamination of D-amino acids."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTDAYVGAIDQGTTGTRFIVFDQHGDVVANTYEKHEQHYPEPGWVEHDPLEIWENTKSVVTAGLSAAGLDADDLAAIGITNQRETTVVWDAASGRPIHNALVWQDRRTTSRVESLEENGKIERIREKTGLEADAYFSATKTEWLLDEAEPLKLSSARASSLRDRARDGELLMGTIDSWLIYNLTGEHITDVSNASRTMLYNITDLEWDDWLLEEFDIPREMLPEVRPSSDEAVYGHTDPDGFLGAAVPVTAALGDQQAALFGQTCFDAGDAKNTYGTGSFYLMNTGEDAVSSEHGLLTTIGFQLSGEPVQYALEGSIFVTGAAIEWLEDVDLINNAAQTAELASSVDTTDGVYMVPAFTGLGAPHWDGRARGTLVGMTRGTRKAHIVRATLESIAYQTRDIAAAMEADSGVSTTTLRVDGGAVKNNFLCQLQSDIIQTDLARPEVDETTALGAAYAAGLAVGYWDSLDDLRENWRVDRSFEPEMDPSEADSKYGRWEDAVDRSLAWATED",
    "output": "Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTTISDIYAREILDSRGNPTVEVEVFLESGGWGRAAVPSGASTGAYEAVELRDKDPKRYGGKGVLDAVNNINAIIAPELVGSDALDQREIDRQLIEMDGTPNKGKLGANAILGVSLAVAKAAADALGLPLYRYLGGVNAHTLPVPMMNILNGGKHADNNVDIQEFMVMPAGASDFASALRMGAEVFHSLKAVLQSKGLNTAVGDEGGFAPNLRSNVEAIEVLLEAIAKAGYEPGKDCFIALDPASTELYKDGKYVFAGEGVTRTSDEMVEFWASLVDKYPIISIEDGLAEDDWEGWQNLTKRLGHKVQLVGDDLFVTNTERLSRGIEMGAANAILIKVNQIGTLTETLEAIEMAKKAGYTAVVSHRSGETEDTTIADIVVAVNAGQIKTGAPSRTERVAKYNQLLRIEEELDAAALYPGLKAFYNLKK",
    "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIIDRVQVEAINSFSNLELLKEVYGLIWILPILTLLLGITIEVLVIVWLEREISASIQQRIGPEYAGPLGLLQAIADGTKLLFKEDILPSRGDIPLFSIGPSIAVISILLSFLVIPLGYRFVLADLSIGVFLWIAISSIAPIGLLMAGYSSNNKYSFLGGLRAAAQSISYEIPLTFCVLAISLLSNSLSTVDIVEAQSKYGFFGWNLWRQPIGFLVFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKYGLFYLVSYLNLLVSSLFVTVLYLGGWNLSIPYISFFGFFQMNKMVGILEMTMSIFITLTKAYLFLFISITIRWTLPRMRMDQLLNLGWKFLLPISLGNLLLTTSFQLVSL",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGCNFSSQSKLQVPEIRASRSITPASQKSEDPYSHIRLLLLGSAESGKTTVLEQVRLLYKQHFTESEYFHRRAFIYHNIFKSIKALCRAMRMSDIQFADPINMGRAQSIIADEHGHYGLFSKDLAEKIKHIWNDKSMQKLYARRSQFNLNDSASYFLNNIDKINMVDYKPSERDLIMAYVPTCGVQNVIFTACNQSFQLFDIGGQKIDRRKWALQYEGIDAIFFCIAISEYDQVMSEDMVTNRLDDALNLLQSISEDPAFATTPIYLFLNEIDVFCEKLSVIPLSKYKPDFKGGDQDDAIDFMENLACEALGKRDRSLYRVYRCIAIDTQMMAELLSTVFKDIAKRKK",
    "output": "Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES",
    "output": "Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are activated through phosphorylation and further phosphorylate additional targets. RPS6KA5/MSK1 and RPS6KA4/MSK2 can directly phosphorylate and activate transcription factors such as CREB1, ATF1, the NF-kappa-B isoform RELA/NFKB3, STAT1 and STAT3, but can also phosphorylate histone H3 and the nucleosomal protein HMGN1 . RPS6KA5/MSK1 and RPS6KA4/MSK2 play important roles in the rapid induction of immediate-early genes in response to stress or mitogenic stimuli, either by inducing chromatin remodeling or by recruiting the transcription machinery . On the other hand, two other kinase targets, MAPKAPK2/MK2 and MAPKAPK3/MK3, participate in the control of gene expression mostly at the post-transcriptional level, by phosphorylating ZFP36 (tristetraprolin) and ELAVL1, and by regulating EEF2K, which is important for the elongation of mRNA during translation. MKNK1/MNK1 and MKNK2/MNK2, two other kinases activated by p38 MAPKs, regulate protein synthesis by phosphorylating the initiation factor EIF4E2 . MAPK14 interacts also with casein kinase II, leading to its activation through autophosphorylation and further phosphorylation of TP53/p53 . In the cytoplasm, the p38 MAPK pathway is an important regulator of protein turnover. For example, CFLAR is an inhibitor of TNF-induced apoptosis whose proteasome-mediated degradation is regulated by p38 MAPK phosphorylation. In a similar way, MAPK14 phosphorylates the ubiquitin ligase SIAH2, regulating its activity towards EGLN3 . MAPK14 may also inhibit the lysosomal degradation pathway of autophagy by interfering with the intracellular trafficking of the transmembrane protein ATG9 . Another function of MAPK14 is to regulate the endocytosis of membrane receptors by different mechanisms that impinge on the small GTPase RAB5A. In addition, clathrin-mediated EGFR internalization induced by inflammatory cytokines and UV irradiation depends on MAPK14-mediated phosphorylation of EGFR itself as well as of RAB5A effectors . Ectodomain shedding of transmembrane proteins is regulated by p38 MAPKs as well. In response to inflammatory stimuli, p38 MAPKs phosphorylate the membrane-associated metalloprotease ADAM17 . Such phosphorylation is required for ADAM17-mediated ectodomain shedding of TGF-alpha family ligands, which results in the activation of EGFR signaling and cell proliferation. Another p38 MAPK substrate is FGFR1. FGFR1 can be translocated from the extracellular space into the cytosol and nucleus of target cells, and regulates processes such as rRNA synthesis and cell growth. FGFR1 translocation requires p38 MAPK activation. In the nucleus, many transcription factors are phosphorylated and activated by p38 MAPKs in response to different stimuli. Classical examples include ATF1, ATF2, ATF6, ELK1, PTPRH, DDIT3, TP53/p53 and MEF2C and MEF2A . The p38 MAPKs are emerging as important modulators of gene expression by regulating chromatin modifiers and remodelers. The promoters of several genes involved in the inflammatory response, such as IL6, IL8 and IL12B, display a p38 MAPK-dependent enrichment of histone H3 phosphorylation on 'Ser-10' (H3S10ph) in LPS-stimulated myeloid cells. This phosphorylation enhances the accessibility of the cryptic NF-kappa-B-binding sites marking promoters for increased NF-kappa-B recruitment. Phosphorylates CDC25B and CDC25C which is required for binding to 14-3-3 proteins and leads to initiation of a G2 delay after ultraviolet radiation . Phosphorylates TIAR following DNA damage, releasing TIAR from GADD45A mRNA and preventing mRNA degradation . The p38 MAPKs may also have kinase-independent roles, which are thought to be due to the binding to targets in the absence of phosphorylation. Protein O-Glc-N-acylation catalyzed by the OGT is regulated by MAPK14, and, although OGT does not seem to be phosphorylated by MAPK14, their interaction increases upon MAPK14 activation induced by glucose deprivation. This interaction may regulate OGT activity by recruiting it to specific targets such as neurofilament H, stimulating its O-Glc-N-acylation. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrinth layer of the placenta. Also plays an essential role in developmental and stress-induced erythropoiesis, through regulation of EPO gene expression . Isoform MXI2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform EXIP may play a role in the early onset of apoptosis. Phosphorylates S100A9 at 'Thr-113' . Phosphorylates NLRP1 downstream of MAP3K20/ZAK in response to UV-B irradiation and ribosome collisions, promoting activation of the NLRP1 inflammasome and pyroptosis .; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSVIGLWLVTVTATLSLFVWQLIFLLSIPKSIVVCLIAESLFFVAWFFYWTVIYPRYLTPFRHLPTPASRSILTGNQNGLFTENSWDVARRVSQTVPNSGLIRYYVALSNERILVTNTRALSDVLTNHSHDFGKSNLAKFALKRLTGNGLGFLEGNEHKVHRKNLMPAFTRKHVKELTPIFWDKAMEMVKGMEAEVRCGKDTSTQGTGIVEIHDWATRATLDIIGTAGFGYDFGTLHNPSNEIGQQYKKMFLEPSTAFNWLELLGNYIDFRFLMTLPVKKNRDLTAGSNFMREIAKKVIRERRHELFQRMTSQAGNMKNTKKDIITTALASDCFTDDQLVDHVMAFLVAGHESTATAFEWAMYELGHRPEMQKRVRDEVRTYLPSPSAGGVKNITFESVPYLQAICNEVLRLYPFLPFATRVAEKDTWVADQFVPKGTIVAYAAHISNRDSELWSGPALDAFDPERWMEPGKESSGGANSNYAMLTFSAGPKSCIGEAWTRAELPCLVGAMVGSFEIELVEGKQADGTVYPTVDFKMGKVLKSRDGVFVRLRRLEDW",
    "output": "Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of fusarielins F, G and H, decaketide compounds with 5 methylations and a decaline core that act as mycoestrogens as they stimulate growth of MCF-7 breast cancer cells . The initial compound in the pathway is produced by the reducing polyketide synthase FSL1. FSL1 lacks an active enoyl reductase (ER) domain and biosynthesis of fusarielins relies on the trans-acting enoyl reductase FSL5, before it is released through hydrolysis catalyzed by the thioesterase FSL2 . Fusarielins F, G, and H have a C11=C12 cis double bond and is fully reduced between C10 and C11 and between C12 and C13. FSL3 can be involved in the formation of the C11=C12 cis double bond by moving a hypothetical C10=C11 or C12=C13 trans double bond to form prefusarielin . Prefusarielin is oxygenated at C15 and C16 by FSL4, resulting in fusarielin F, which subsequently is epoxidized into fusarielin G by the same enzyme . The final step in the pathway is a reduction of the carboxylic acid moiety to yield fusarielin H via a still undetermined mechanism ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTDVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAGSGQNPARQAAIKAGLPAMVPAMTINKVCGSGLKAVMLAANAIMAGDAEIVVAGGQENMSAAPHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEFAVGSQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKPAFDKAGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPVPASKRALSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILVTLLHEMKRRDAKKGLASLCIGGGMGVALAVERK",
    "output": "Catalyzes the condensation of two acetyl-coA units to form acetoacetyl-CoA . Is involved in the biosynthesis of polyhydroxybutyrate (PHB), which is accumulated as an intracellular energy reserve material when cells grow under conditions of nutrient limitation . Also catalyzes the reverse reaction, i.e. the cleavage of acetoacetyl-CoA, and is therefore also involved in the reutilization of PHB ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWKGMGNNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLKLRLKANPVPVVVPIGAEENFKGVVDLLKMKAIIWDEASQGTKFDYVDIPAELADTCQEWREKMVEAAAEASEDLMNKYLEEGDLPEADIVKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELESGEAAERQASDEEKFSSLAFKIMTDPFVGQLIFFRVYSGVVNSGDTLLNSTKGKKERLGRILQMHANQREEIKEVRAGDIAAAVGLKEATTGDTLCDPAHPIVLERMVFPEPVISQAVEPKTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEATVGKPQVAYRETIRSTAKDVDGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVIPREYIPAVDKGIQDTLKSGVLAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAMRRANPVVLEPMMAVEVETPEDYMGNVMGDLSGRRGIVQGMEDMVGGGKIVRAEVPLSEMFGYSTSLRSLTQGRATYTMEFKHYAEAPKNVADAIISAKSK",
    "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTVGSGHRWPEPSMHPTEIAYAKINLALHVRRRRADGYHDIETIFAFAEHGDIVAAEPGPARLMLAGPFAPALAGEDPEDNLVMRAADGLCALAGEAARPAIRLDKRLPVAAGIGGGSADAAAVLRLLGRAYGIAADDPRVMTLAATLGADVPACVRSATVRGGERGDRLESIAADGLHGLPLLLVNPRVALPTGPVFAAWDRVDRGPLAPGDPLAAALAGRNDLEAPATLLHPVIGEVVTLLAAQPGAILARMSGSGATCFALFGSEADRDAADRALAHRRPDWWRLTSRLR",
    "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQPPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGANLLQLLEGRLDNVVYRMGFGATRAESRQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAVKMEGVFKRIPERTDLSADINEHLIVELYSK",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNLHEYQSKKLFADYGLPVTKGYVCENVEQALSAIEKLSGSQWIAKCQIHAGGRGKAGGVKVVKSAQEVRSFFTKFLGQRLVTVQTNEQGQPIHQIYLEPCAEIQKELYLSAIIDRSSQRIVFMASSEGGMDIEEVAEKTPHLLHRVTIDPLVGAMPYQGRELAFKLGLSGKQIQQFSQIFCQLAKLFVEKDLSLLEINPLVILKNDELFCLDAKVVVDDNALYRHPDLFSMRDLTQEDPREAEAEKWNLNYVALDGNIGCMVNGAGLAMGTMDIIKLHGGRPANFLDVGGGATKERVMEAFKIILTDSAVKAVLVNIFGGIVRCDLIAKGIVSAINEIGVSVPVIVRLEGTNADLGCEILAQSNLNLIAVNSLTEAAEQAVNAAKESE",
    "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQYSSKKNSYEDQNFQNRFFNSLNGQNKSSLNQNSSFSESSKQQVVSITYEEIGLFPRSFNRVFDRFFKQLFFDVENLVIQEYRFYRYLFLTTVKCLFILLFVPLGINFLSKNYLIRPVTEYYWNTHNHEIFLNSYQQKRAFTELKNFEEKIYFESLLLSENQIFFGLSEKNSTFPSSEKSQKSEHFSNQDEHTNDFYGKPKKFQTDSSLQQKNEEKVFLFENSKSLAFEPNLNQIHSSGFLIASADFSKNEVQNFQNLNLSNNTSQSKTDFASVFRTSVQKRLQVKILELAKHYNEESIEAITNFFADVLSFITLCYLLVRLEIQINITKSFLLEVFFGLDDSKKSLLILFITDLLVGYHSPNIWELFFQTLFDHYGLPESQTTIFLLVATLPVLLDVLFKYLIFRHLNRASPATVATYHAMIE",
    "output": "May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake into chloroplasts."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATNNGDVLMLEATPEAARPWASAANAEVIDALPYIDDDYGNPLIKSEVDRLVEEEMRRSSKKPADFLKDLPPLPKFDFKNCPVLGKEYERVRAGKPPVRIDFESRYKLEMPPANKRNDDAAWKQYLQKNQRSLQQKLIELENLELMSKLGPELWRQNNHRLEVFLTRMQRLAQEQNEEIEKVNRERKYHQQTTSYELNALSQEWRQLCVKNMEIQSACAMLETQIDSFKKEAAERGWNLEEKLENVEPLQMQ",
    "output": "Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. Involved in mRNA splicing."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTTLTTLLALADSRLPIGGHVHSGGVEEAVTSGLVTNLETLHAYLVRRVRTQGLVAASIAAAVHAGTLTVAAADRETDARTPAPAARTASRAQGRGLARLARRVWPGHDWTALGRAPHLPVASGAVGAVAGLTPGQTALSVVYTTMTGSATAAQRLLALDPGDVAALTFGLAPLCDDVAAAAAEEPADLSDPLLDVLAQRHSERERPLFAS",
    "output": "Required for maturation of urease via the functional incorporation of the urease nickel metallocenter."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVNMKASMFLTFAGLVLLFVVCYASESEEKEFPKEMLSSIFAVDNDFKQEERDCAGYMRECKEKLCCSGYVCSSRWKWCVLPAPWRC",
    "output": "Ion channel inhibitor."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEARAILRHTPTSPRKMRLVADLVRGKQVDAAKAMLAHSTKHAARTVLQTLSSAVANYSQANPEKRLDESELIVKRIYVDQGVTLKRILPAPMGRAYRVRKRANHLTIIVDEANPTDEQN",
    "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSRIALGLAYDGSAWQGWQTQPHGVTVQDQVEAALASFAGGGGPVATVCAGRTDTGVHAAMQVIHLDTDLQRRDESWVRGVNAFLPPSIVVQWARPVSEAFHARFSARSRTYVYLLWRGRVRPALWAGRAGWAFQPLDVPAMRAAARALLGEHDFSSFRSSQCQARHPVRTLHRLDIDERGAFLVFTLRANAFLHHMVRNLIGALLQVGQGREPVAWMDALLCARDRRLGAPTFMPDGLYLSAIEYPAEFGFDELDGGITLLSPFTGALG",
    "output": "Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAAATGTRKKKTPRPGQWKLWLLYTAGFVPAVWTFYLGATGQLGADPVKTFEHLLGLWALRFLILTLLVTPIRDLTGITLLRYRRALGLLAFYYALMHFTTYMVLDQGLNLSAIITDIVRRPFITIGMISLALLVPLALTSNNWSIRKLGRRWSSLHKLVYIAIAGSAVHFLMSVKSWPAEPVIYAAIVAALLLWRLARPYLRTRKPALRPRGEAIALRK",
    "output": "Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MHLEAARVIFFLWIFLQVQGIKDLSIKIYGSEIKDIDNAPRTEATKNTAKTYKVSTMRRIFDLAKHRTKRSAFFPTGVKVCPQESMEQILASLQAYYRLRVCQEAVWEAYRIFLDRLPEPGEYQDWVSVCQQETFCLFDIGKNFSNSQEHLDLLQQRMKQRNFLERKDEVVTKETLGELGQTPGLQQTLPVSHPGPCLSLPMTTAQRNPQLHPSRTPRVPTRERKIEFTDAAEDALEQKVELSISLANQKFKSELDNSQSPYYLEVAAKSQLQMQKIFKKLPGFKEIHVSGFRPKKERDGTSSTEMQLTAIFKKGKAEAKSPASDPLSLDSNKIESEGDPRGTTEEEKQRELYPTASELRKLISRALEEDQSLDVGTIQFTDEIVGSLPSLDPDTQLVLPTLLTDITKDATLSPELPLGQPRLETVDRAGHSPPGASPTDGWSPPAMTSTSLSETLPFFTASSVFPQTDQSATDIMSIDQTVLIPRLTVPTDDYSAISPLVPEISHLPTSSEDWLSTSSQDTMEYLDGVDLTKTPTSSEGPRNSVGMFPAWIIFLENITPDPGLRYITTSAMTVAARGRELVVFFSLRVANVPFSTDLFNKSSLEYQALEQRFTQLLVPNLRSNLTGFKQLEILNFRNGSVIVNSKVRFAKSVPYNLTKAVRGVLEDFRSTAAQQLDLEIDSYSLDVEPADQADPCKFLACGEFAQCVRNEWTEEAECRCRSGTQALVLPIEDCEDIPGKGTPCRSLDQSKNQVYEPGVKKFQRQQDNKVTMKRKFELLTIGYEEFNYQDWEGN",
    "output": "Chondroitin sulfate-, heparin- and hyaluronan-binding protein (By similarity). May serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKGCIFNIDAGYLEGLCRGFKCGILKQSDYLNLVQCETLEDLKLHLQGTDYGTFLANEPSPLSVSTIDDKLREKLVIEFQHLRNHSVEPLSTFLDFITYSYMIDNIILLITGTLHQRPISELIPKCHPLGSFEQMEAIHVAATPAELYNAVLVDTPLAPFFVDCISEQDLDEMNIEIIRNTLYKAYLEAFYDFCKQIGGTTADVMCEILAFEADRRAIIITINSFGTELSKDDRAKLYPRCGKLNPDGLAALARADDYEQVKAVAEYYAEYSALFEGAGNNVGDKTLEDKFFEHEVNLNVHAFLQQFHFGVFYSYLKLKEQECRNIVWISECVAQKHRAKIDNYIPIF",
    "output": "Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). May play a role in coupling of proton transport and ATP hydrolysis (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLKPLGDRVIISFVETEEKSVGGFVLAGASHDATKTAKVLAVGDGIRTLTGELVAPSVAEGDTVLVENDAGLEVKDGNEKVTVVRESDIVAVVK",
    "output": "Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGRVQKVMIPPINFIFKLLQQHTPVSIWLFEQTDIRLQGQIRGFDEFMNIVLDDAVQVDAKNNKRELGRILLKGDNITLIQAI",
    "output": "Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPDYAIGDVQGCYDPLQRLLELIDFNEKEDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPKITLGNHDLHLLGLLFGGQPWKGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMCHAGIAPLWDLSKAVGLANELEAVLSGDSYHEFFAQMYGNKPDIWSDDLVGLDRLRVITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGRSSHPRIHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE",
    "output": "Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAQKAPMTVTFVTGNQNKLKEVRAILGEEHADKFTLEARKVDLPELQGEPEDIAKEKVMLAARQIDGPTLVEDTSLCYNALQGLPGPYVKWFLDKLGHEGLNKMLAGYDDKSAYAQCVFAYVDGPNGEPKVFVGTTDGKIVPARGPTDFGWDPVFQPDGFEETYAEMDKAVKNGISHRYRALDKFREFILAEAAGR",
    "output": "Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGRITEDLIRRNAEHNDCVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIERIENLEGCEWLTKLDLTVNFIGELSSVKTLTHNIHLKELFLMGNPCADFDGYRQFVVVTLQQLKWLDGKEIERSERIQALQNYTSVEQQIREQEKAYCLRRAKEKEEAQRKLEEENESEDKKKSSTGFDGHWYTDIHTACPSATENQDYPQVPETQEEQHNTKESDDIEDDLAFWNKPSLFTPESRLETLRHMEKQRKAQDKLSEKKKKAKPPRTLITEDGKVLNVNEAKLDFSLKDDEKHNQIILDLAVYRYMDTSLIEVDVQPTYVRVMVKGKPFQLALSTEVQPDRSSAKRSQTTGHLLICMPKVGEMITGGQRTPTSVKTTSTSSREQTNPRKKQIERLEVDPSKHSCPDVSTIVQEKRHRPKRMESQPRDEPSEEDPDFEDNPEVPPLI",
    "output": "Involved in dynein arm assembly, is important for expression and transporting outer dynein arm (ODA) proteins from the cytoplasm to the cilia . Acts as a crucial component in the formation and motility of spermatozoal flagella (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKVAASSLRKGSVVDMDGKLYVVLSAENIHPGKGTPVTQLNMRRISDGVKVSERYRTTEQVERAFVDDRNHTFLYSDGDGYHFMNPESYDQLVATEDVIGDAAPYLQEGMTVILSTHNDVPIAIDLPRTVVLEIVDTEPSVKGQTASSSYKPAVLSNGVKTTVPPYITAGTKVVILTEDGSYVERAKD",
    "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVAALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLVMLTALSALVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVASILILAIIPILHTSKQRSMMFRPLSQYLFWLLVATLFTLTWIGGQPVEHPYIIIGQTASILYFLIILVFMPTISIMENYLLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPIFPKPKVTVILANLGTPDVPTASAVRAFLKQFLSDQRVIEIPKLLWKIILYSFVLPFRPKRVAHAYASVWGQDSPMREILFAQTDALKRQLISHYPQLDLNIVPAMTYGNPGVQHILKDLAASPQEHVILLPLFPQYSATSTAPLYDAFANWIPKQRHLPGLTIIKDYYRHPVFIQALVSSVQRFQQQHGKPQKLLMSFHGIPQPYADKGDPYADRCRETARLVAKQLGLTPDDWAISFQSRFGKQEWVKPYTDELLTTWAANGIKSVQILSPAFSADCLETLEELEIQNAELFLEAGGTSYQYIPALNTSVEHLELLRQLLQAHLDALNYSLAYSAH",
    "output": "Catalyzes the ferrous insertion into protoporphyrin IX."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKYIEIEGVLHEFSAVDNVVEDVSTIIMNIKQLALKIYSEEDKTLEIDVRDEGEVTASDITHDSDVEILNPELKIATVSKGGHLKIRLVANKGRGYALAEQNNTSDLPIGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKIMTEHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSLVHMNIGLAFTVAFLGLLMYRSHLMSSLLCLEGMMLTLFIMSSIMVLNMHFTLASMLPIILLVFAACEAAVGLSLLVMVSNTYGVDYVQNLNLLQC",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGKAKFPRQLKDNEAKAVARTIRVSPQKLNLVAAMIRGKKVGAALADLTFSRKRIAGTVKKTLESAVANAENNHDLDIDSLVVAEAYVGKSIVMKRFHVRGRGRASRIERPFSHLTIIVREVIEKVEVA",
    "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVSLQFITHQTDRYTYFESALMALEGGCKWIQLRMKEAPCEEVEAVALQLKPLCKEKEAILLLDDHVELAKKLEVDGVHLGKKDMPIDQARQLLGEAFIIGGTANTFEDVVQHYRAGADYLGIGPFRFTTTKKNLSPVLGLEGYTAILSQMKEANIELPVVAIGGITREDIPAILETGVNGIALSGTILRAEDPAAETRKILNMKRIIK",
    "output": "Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTVRDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSLGKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELSSNSEQGQSVPLNTSTTTDPATTSTPPASVDTTATNTQTPAVTAPAPAVDPQQNAVVSPSQANVDTAATPVPTAATTPDGAAPLPTDQAGVTTPAADPNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQSPAQ",
    "output": "Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYLLDEKDVSPYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADRIGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKEATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHVDEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTIFLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIREIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLSYLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSKKVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENIDEFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIVFIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQSNMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVSSSDWNVGDKVMHKAWGEGMVSNVNEKNGSIELDIIFKSQGPKRLLAQFAPIEKKED",
    "output": "Essential helicase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAGGGKHTPTPKAIIHQKFGAKASYTVEEVHDSSQSGCLGLAIPQKGPCLYRCHLQLPEFSVVSNVFKKKKDSEQSAAELALDKLGIRPQNDDLTVDEARDEIVGRIKYIFSDEFLSAEHPLGAHLRAALRRDGERCGSVPVSVIATVDAKINSRCKIINPSVESDPFLAISYVMKAAAKLADYIVASPHGLRRKNAYPSEIVEALATHVSDSLHSREVAAVYIPCIDEEVVELDTLYISSNRHYLDSIAERLGLKDGNQVMISRMFGKASCGSECRLYSEIPKKYLDNSSDASGTSNEDSSHIVKSRNARASYICGQDIHGDAILASVGYRWKSDDLDYDDVTVNSFYRICCGMSPNGIYKISRQAVIAAQLPFAFTTKSNWRGPLPREILGLFCHQHRLAEPILSSSTAPVKSLSDIFRSHKKLKVSGVDDANENLSRQKEDTPGLGHGFRCEVKIFTKSQDLVLECSPRKFYEKENDAIQNASLKALLWFSKFFADLDVDGEQSCDTDDDQDTKSSSPNVFAAPPILQKEHSSESKNTNVLSAEKRVQSITNGSVVSICYSLSLAVDPEYSSDGESPREDNESNEEMESEYSANCESSVELIESNEEIEFEVGTGSMNPHIESEVTQMTVGEYASFRMTPPDAAEALILAVGSDTVRIRSLLSERPCLNYNILLLGVKGPSEERMEAAFFKPPLSKQRVEYALKHIRESSASTLVDFGCGSGSLLDSLLDYPTSLQTIIGVDISPKGLARAAKMLHVKLNKEACNVKSATLYDGSILEFDSRLHDVDIGTCLEVIEHMEEDQACEFGEKVLSLFHPKLLIVSTPNYEFNTILQRSTPETQEENNSEPQLPKFRNHDHKFEWTREQFNQWASKLGKRHNYSVEFSGVGGSGEVEPGFASQIAIFRREASSVENVAESSMQPYKVIWEWKKEDVEKKKTDL",
    "output": "Methyltransferase that adds a methyl group to the ribose of the last nucleotide of small RNAs (sRNAs). This protects the 3'-end of sRNAs from uridylation activity and subsequent degradation. Can methylate 3'-end of microRNAs (miRNAs), small interfering RNAs (siRNas) and trans-acting small interfering RNAs (ta-siRNAs). Involved in plant development through its role in small RNAs processing. Required for the specification of reproductive organ identities and the probable repression of A class genes. May control floral determinacy possibly by regulating the expression of the C class floral homeotic gene AGAMOUS (AG)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATFNLTIVSAEQKIFEGEVKQIQVTGVEGELGILPGHTPLLTAIKPGIVKFTLKDGNEEVIYVSGGFLEVQPNIVTVLADIAIRGSELDADRIHEAKRKAEENIVSRGSDADHDLLVAKLSKELAKLRAYELTEKLLKTRR",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAVSEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVIDGSVRGRLERLADVLQS",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEIALSYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVATTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRAIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK",
    "output": "Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFKSGFVTIIGRPNVGKSTLLNHIMGEKLSIVSSKPQTTRNNIQTILTGEEYQIVFVDTPGMHNPRHKLGEYMVKVAKESMNEVDVALFVTTPDVEVKRGDLHILEQLKSAKVPVFLVVNKIDETTEERLAATLKNYSEAFEFQEIIPISAQKGKNVDKLIELMVKHLNEGPKYYPDDMIIDKQERFIIAEIIREKALRFLSQEVPHGIAVEILQMKEENEKYKIEATIMCEKDSHKGIIIGKGGEMLKKISQSARKSAEKFLDKRVNMKIWVKVKKDWRDSPFVLGELGYKAPKK",
    "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALSGILSKRVIAHRADENELEDDFSSSEELNTLGSEDDEDEDEDEDEGEGEGDESENEEAPDNASSEDDGDNDIKSSLSQISFGALAKAQQSLGPLKKGAKRKHGSEEEEEEDNKNTKYKKSKSDALNELRERIRRAKEEKASKSEGSRDNELLDKKHKEARSSKHAPAVQSSKYAVSRRRVVVDGENVAQVKSRDPRFDSAVQSYSHNAKSSSYATSHSDLAAAKNYAFLNEYRDAELKELEEKLRRSKKDDEKARLKKMITSMKDRKRAMENRERERQVLAKHRKKERELIKEGKKEKAWFLKKADLKKEALKEKYESMGAKERQKGIERRRKKVASKEKKEMPRSRRMVEG",
    "output": "Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARVTVEDCLEKVDNRFLLVMLASKRVKQLFKGARPLIDNRGANKNVVVSLREIAAGKIGCEIGKKGR",
    "output": "Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNFKLRTLLAFSLVLFLGIVSSSPIVPHYLRAIDVSKAVTPKQVENDLGKVLSKGTLIFGPSNPAFADATERWSTHSMPADIQVVIEVAQESDVAKVVKYCHQNNINFLAYTRGHGSTNTVSKFKGIEINLSKLTGIAIQPDKKSALFQGGVYADLIINKLWSQGYIVPTGSNGCVGLFGPALGGGLGRYQGQYGLISDNFVSLNVVLANGTSTTVNAISNSDLFWAMKGAGHNFGIVTSAYIKIYPRKAKTWHYHNYVWSQDKLEKVFEALNRFQGKGQIPALMGVNFGQFSIEPRISETEAVIIWSFAYDGPAAAAEKLLAPFNAIFAISSTKGDVSYSELLVAQQTDINSSSCSSQPYVGSTTWLQTYNVTSQRAIYDLFNKQIAQNPGLAPGARVFFEGYSTKATQTIDPNSSSYPHRDEYLLVFFAVVTPPSLESVGRAWADKTLAIWHASQPGRRPATYVNYAVGNEPLESIYGYNGQLTKLRALKSKYDPLNKFRWYNPIVAY",
    "output": "FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of virensols and trichoxide, fungal natural products that contain or are derived from a salicylaldehyde core . The pathway begins with the synthesis of the reduced chain in virensol C by the highly reducing polyketide synthase virA via condensation of one acetate and 8 malonate units . VirA has interesting programming rules since the first 2 ketides are fully reduced, the 3 following ketides undergo beta-dehydration, and the last 3 ketides are only reduced to beta-hydroxys to yield the trihydroxy portion . The production of aldehyde virensol C by virA alone is surprising, since virA does not contain a reductase (R) domain that is typically associated with reductive product release in HRPKS . The cupin-domain enzyme virC is involved in enhancing virA product turnover . The short-chain dehydrogenase virB then oxidizes the C-7 alcohol of virensol C to a ketone, yielding virensol D . Virensol D is further transformed to salicylaldehyde 5-deoxyaurocitrin by the short-chain dehydrogenase virD . VirD catalyzes the dehydrogenation of C-3 to form the beta-ketone aldehyde, which is followed by the generation of the nucleophilic C-2 that is required for the intramolecular aldol condensation between C-2 and C-7, itself followed by dehydration and aromatization which leads to salicylaldehyde 5-deoxyaurocitrin . While the dehydrogenation of virensol D is definitely catalyzed by virD, the aldol condensation and dehydration may be uncatalyzed or assisted by virD . The short chain dehydrogenase virG then converts salicylaldehyde 5-deoxyaurocitrin into virensol B which is further hydroxylated by the cytochrome P450 monooxygenase virE to yield the hydroquinone virensol A . VirI then may oxidize virensol A to form the quinone, while virH performs the epoxidation . Finally, the two remaining short-chain dehydrogenases, virK and virL, are probably responsible for reducing the ketones to the corresponding alcohols to furnish the epoxycyclohexanol structure in trichoxide ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDGTTTTLPLAGIRVIDAATVIAAPFCATLLGEFGADVLKVEHPIGGDALRRFGTPTARGDTLTWLSESRNKRSVTLNLQHPEGARVFKELIAHSDVLCENFRPGTLEKWGLGWDVLSKINPRLIMLRVTGYGQTGPYRDRPGFARIAHAVGGIAYLAGMPKGTPVTPGSTTLADYMTGLYGCIGVLLALRHREQTGRGQYIDAALYESVFRCSDELVPAYGMYRKVRERHGSHYNEFACPHGHFQTKDGKWVAISCATDKLFARLANAMGRPELASSSVYGDQKVRLAHASDVNEIVRDWCSSLTRAEVLERCYATATPAAPLNDIADFFGDRHVHARRNLVAIDAEDLGETLIMPNVVPKLSETPGSIRSLGPKLGEHTEEVLKEILGMCDEQINDLRSKRVI",
    "output": "Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation. Catalyzes the transfer of CoA moiety from succinyl-CoA to L-malate to yield L-malyl-CoA. It is highly specific for succinyl-CoA as the CoA donor, however it can accept L-citramalate instead of L-malate as the CoA acceptor."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRVKGIRKNYQHLWKGGILLLGTLMICSAVEKLWVTVYYGVPVWKETTTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLENVTEDFNMWKNNMVEQMQEDVINLWDQSLKPCVKLTPLCVTLNCKDVNATNTTSSSEGMMERGEIKNCSFNITKSIRDKVQKEYALFYKLDVVPIDNKNNTKYRLISCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGKGQCKNVSTVQCTHGIRPVVSTQLLLNGSLAEEKVVIRSDNFTDNAKTIIVQLNESVKINCTRPSNNTRKSIHIGPGRAFYTTGEIIGDIRQAHCNISRAQWNNTLKQIVEKLREQFNNKTIVFTHSSGGDPEIVMHSFNCGGEFFYCNSTQLFNSTWNDTEKSSGTEGNDTIILPCRIKQIINMWQEVGKAMYAPPIKGQIRCSSNITGLLLTRDGGKNESEIEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGIGALFLGFLGAAGSTMGARSMTLTVQARQLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLAVERYLKDQQLMGIWGCSGKLICTTAVPWNTSWSNKSLDSIWNNMTWMEWEKEIENYTNTIYTLIEESQIQQEKNEQELLELDKWASLWNWFGITKWLWYIKIFIMIVGGLIGLRIVFSVLSIVNRVRQGYSPLSFQTLLPATRGPDRPEGIEEEGGERDRDRSGQLVNGFLALIWVDLRSLFLFSYHRLRDLLLTVTRIVELLGRRGWEILKYWWNLLQYWSQELKNSAVSLLNATAIAVAEGTDRIIEVVQRVYRAILHIPTRIRQGLERALL",
    "output": "[Envelope glycoprotein gp160]: Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MELELLFQNVVNSSAFYNNQVAVAVSGGVDSIVLLHLMTNWAKKNKLSLPIALTVNHGLRPESQKEADFVVSYAKELGAKESFILNWEKQNIKGNIQLQARKARYKLLAEWCKNNNVKYLLVAHHKDDQAETFLLRLERGSGVDGLSSMDYKSFLNGIDIFRPLLNFSRSEIEKYAKLHRLKWIEDRSNHDLKYRRTLYRNLLKASDNQEILTERICLTALHMKRAAKALMHYTRLAFNDCVNVHDLGYIEIKLSEFYQLPEEIALRLLLYSIMAIASKHYKPRYSSLIAIFNRILQKDSNVNCTLSGCKIRKYGENILIIRESSRIQEITVNLPLNEPTQWDNRFSCTILGNQGCSVIIAPLKKTQKVPEFLKDYNCCPEVFYSLPTVQKDSKVLAYPDVNYNGKNTNDDKVQCIINSTIKQNLVSLISI",
    "output": "Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGKIPKYFITELLSRTNIIELINTRLELKKYGKNYQTNCPFHHDKTPSFTVSNEKQFYYCFGCNAHGNAIDFLIQYEHLSFIESIEELALIHGVKIPFENTVQNSIYVKKQKLYLLMEKICKLYKKNINVTHLANKYLARRGINQNMIDFFLIGFSSLKWNEFYKKINISKEFEQELLINNIIATDKNGYIYDRFQGRIIFPIQDNHGRIIGFGGRSLNDMSPKYLNSPETDIFYKRKQIYGLYQVIKKCSKPVYLLVVEGYIDVITLTQYNIDYAVSILGTSTTTEHIQLLFKNTDIIICCYDGDDAGKNAAWKTLKKALPYISDKKTLKFILLPNQEDPDTIIRKEGREKFQKRIDNAITMSKFFFKNILKNINLSSDDDKFHLSVHALPLINTISSDTIRIYLRQILARMIGILDDNQFEKFLYEKETKNTQKTYFQIKRTPMRTLIGLLVQNPSLAKLVPVTMKFKNLQIKGLSIFLEILQTCRDNPNIHTGQLLELYRNTTIINVLKILARWDHMIIQKETQNMFLDLLMNIHDKILEKRREYLIAKERKKGLQMNEKKEIWSINKKLSKR",
    "output": "RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKRKTSPILSWLLTIGFAFIAFIAVFPLLNLILASFRPSTELMRNGITLIFDPSTLTLDNFIYIFTEAGLYWTWFGNSVWISIVIVVLSLLFSSMVGYALAVYDFKGRNFFFLLVLIILMIPFEILMLPLFQLMIKLQLVNTYTAVILPAIVAPIAVFFFRQYALGLPKELMDAARIDGCTEYGIFFKIMLPLMGPSLAAMAILQGLNSWNNFLWPLVVLRSNDMFTLPIGLATLLTPYGNNYDILLAGSVMTIVPIVILFIFFQRYFIAGLTVGGVKG",
    "output": "Part of the ABC transporter complex AraNPQ involved in the uptake of arabinooligosaccharides (By similarity). Responsible for the translocation of the substrate across the membrane (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVELESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA",
    "output": "Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MANKREFPLERTRNIGIMAHIDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMAQEQERGITITSAATTAAWKNHRINIIDTPGHVDFTIEVERSLRVLDGAVAVLDAQAGVEPQTETVWRQASDYDVPRIVFANKMDKLGADFDFSVQSIHDRLQANALPIQMPIGAEDDFQGIIDLVEMKADLYDVDELGTEWETVDVPDEYKEEAEKRRNEMIEQLADIDENIMEKYLGGEDISVAEIKAAIRKGTLALELFPVLAGSAFKNKGVQMMLDAVVDYLPSPLDVKPYSATDPETGDQVELIAGDDKSFAALAFKVATDPFVGRLTFIRVYQGTLESGSYVLNATKGKRERVGRLLQMHSNQRQEIPEVFSGDIAAAIGLKNTTTGDSLTDPAHPLQLESMVFPDPVIEVAVEPKSKADQDKMDIALQKLAEEDPSFRAETNPETGETVIAGMGELHLDIIVDRMKREFNVEATIGAPQVSYREAFTKKTSAQGKFVRQSGGKGQYGDVWVEFEPNEEGKGFEFEDAIVGGVVPREYIPSVEEGLREAMNNGVLAGYPLVDVKAKLYDGSYHDVDSSEAAFKVAASLALRAAAKTAAPVILEPIMKVEIRVPEEYMGDIMGQVTARRGRVDGMEAIAGAEEIHAFVPLSEMFGYATTLRSASQGRGTFTMTFDHYEAVPKSIQEEIIKKNGGHAE",
    "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDLISHQPNKNPNSSTQLTPPSSSRYENQKRRDWNTFCQYLRNHRPPLSLPSCSGAHVLEFLRYLDQFGKTKVHHQNCAFFGLPNPPAPCPCPLRQAWGSLDALIGRLRAAYEENGGPPEANPFGSRAVRLFLREVRDFQAKARGVSYEKKRKRVNRQKPQTQPPLQLQQQQQQPQQGQSMMANYSGATV",
    "output": "Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to continuous red (cR), far-red (cFR) and blue (cB) light in a phytochrome-dependent manner, at least during seedling development."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSETIPKKPLKKGSLVFVDKNIYDKSIEALASDSDLPAYIFEGPGEILGIKEEYAQVRWRRPVPDVWFKLDQLKEYLASE",
    "output": "NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSYAVIVTGGKQYKVAEGEFLKIEKLEVATGESVTFDRVLLVANGEEVTIGAPVVAGAKVVAEVVSQGRHDKVRIIKFRRRKHHMKRMGHRQWFTEIKITGIQA",
    "output": "This protein binds to 23S rRNA in the presence of protein L20."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "METAEGPHLVRLYVYDMSRGLARRLSPVMLGKQLEGIWHTSIIVFDEEFFYGREGITSCLPGRTMLGEPDSVMELGITEVTEEIFLEYLSSLGESGFSGESYHLFDHNCNTFSNEVAQFLTGKKIPSYITELPSEVLSTPLGQALRPLLDSVQIQPAGGNIFNRQSGPS",
    "output": "Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins (By similarity). Has isopeptidase but not SUMO-processing activity (By similarity). Collaborates with ubqln4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAAEKCAEEFGDSSAASLKIVPKDYAYPLLEDPQGALTTPTEGGRTLVTRGGFNYFHYGCDGHQDAGWGCGYRTLQSAISWIQRRQGSSGHVPSIREIQQILVAIGDKGPEFVGSRDWIGTLEEFYVIDVLHQVPCKILHAKELSSDEILGELRSYFEKYQGFVAMGGLSDTASKAITGYHCSARGRIFLQVVDPHFVGVPSSRQHLIDLGYVRWVPVDEFAGSTYNLCLILQP",
    "output": "Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MADGAGIDRKADEKIQFSTSKEVTVHPTFESMSLKESLLRGIYAYGYESPSAVQSRAIVQICKGRDTIAQAQSGTGKTATFSISMLQVIDTAVRETQALVLSPTRELATQIQSVVMALGDYMNVQCHACIGGTNVGEDIRKLDYGQHIVSGTPGRVADMIRRRHLRTRHIKMLVLDEADELLNQGFREQIYDVYRYLPPATQVVVVSATLPYDVLDMTTKFMTDPVRILVKRDELTLEGLKQYFIAVEKEDWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMREANFTVSSMHGDMPQKERDSIMQDFRQGNSRVLISTDVWARGIDVQQVSLVINYDLPSNRENYIHRIGRSGRFGRKGVAINFVTSEDVRILRDIECMWLPSPCFSCG",
    "output": "ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTATLERRSSQGLWDRFADWVTSTNNRFYVGWFGVLMIPTLLSATICFVVAFVAAPPVDMDGIREPISGSLLYGNNIITGAVIPSSNAIGLHFYPIWEAASMDEWLYNGGPYQLVVFHFLIGVFCYLGREWELSYRLGLRPWICIAYSAPVAAAAAVFLIYPIGQGSFSDGMPLGISGTFNFMFVFQAEHNILNHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETSMEESQNYGYKFGQEEETYNIIAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGISVMAFNLNGFNFNSSIVDSQGRAIYTWADIVNRANLGMEVMHERNAHNFPLDLAGTESAPVAVGNADLNG",
    "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFDAAPIKKVSVVIPVYNEQESLPELIRRTTAACESLGKAWEILLIDDGSSDSSAELMVKASQEADSHIISILLNRNYGQHAAIMAGFSHVSGDLIITLDADLQNPPEEIPRLVAKADEGFDVVGTVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYGCMLRAYRRPIIDTMLRCHERSTFIPILANIFARRATEIPVHHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSLLGSVIAIGGFSLSVLLIVLRLALGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQQVIYPESTPFTEESHQ",
    "output": "Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKTSMVAKQQKKQKYAVREYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVRKASW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQEHQADQLAALSEQE",
    "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIGTILAVGFGGFLGAISRMLTSSFFNKIIPHDFPYGTLLVNIIGSFLMGLFFSYASSKGVHIFTKSLISTGFLSAFTTFSTFSYENLLFLQSGDYFHFFLNIILNVILCLLAVWIGFLIFK",
    "output": "Important for reducing fluoride concentration in the cell, thus reducing its toxicity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRTNPTTSRPGVSTIEEKSTGRIDQIIGPVLDVTFPPGKLPYIYNALVVKSRDTDGKQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTSATFPIHRSAPAFIELDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNLEESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKKGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLASKGIYPAVDPLDSTSTMLQPRIVGNEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEASTKAINLEEENKLKK",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGDVLVVFRVLPEDVDNDLSRLESKIREKLNGVCKINDIKTEEIGFGLKALNVQAIMPDEEGMADRVESILAGIEGVSQVDTKDISLI",
    "output": "Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEEFQVYLELNRSRRHDFLYPLIFREYIYALAHEHGLNKSMIFFENQGYGNKFSSPIVKRLILRMDQQNRLISSANDSNQNPVFGHNNNLYSQMIAAGFAVIVEIPFSLRLISYSQGAEAAKSHNFQSIHSIFPFLEDKFSHLNYVLEALIPHPIHLEILVQALRYWVKDACSLHLLRFSLYEYCNLKSFITPKKSISIFNPRLFLFLYNSHTCEYESIFLFLRNQSSHLRSTSSGVFLERIFFYGKIKYLGEVFYNDFQNNLWLFKDPFIHFIRYQGKSILASKDTSLLINKWKYYFVDLWQYYFYLWSQSGRVRINQLSKYSLDFLGYLSSVRLNPSVVRSQMLENSFLIDNAVKTLDTRIPIISLIGSLSKAKFCNTLGHPISKPTWADSPDSDIIDRFVRISRNLSHYHSGSSKKKSLYRIKYILRFSCVKTLARKHKSTVRAFLKKLGSEFLEEFFTETEEEHVFSLIFPRGFFALRKVYRGRIWYLDIICINALVNHS",
    "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEAGCEGSSPQTLGERTMGEEGERVKPFTPEKAKEVIMSLQQPAIFCNMVFDWPSRHWTAKHLSKVLEGKQIRFRMGLRSTGTVPQFETECSYVDATLEEFLAWNCDQSRISGPFKKYDHSKFWAYADYKYFVTLFEDKTDVFQEVMWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFQKARRHMVTLSPGQVLFVPRHWWHYVESLDPVTVSINSWIELEEDHLARVEEAVTRMLVCTLKTAEDPHHPRTWLNPTEVEETSHEVNSCYLNSAVCAFFDHCERAKEVEMQAPRANGEEPGVQEHMEVEQARDPSSDVGAGKQEAASPFGPDLVPVTPASEERGGALEGDSQECTSRNGEHCAELPCARRQQASKGARAEAGQSAPRYPVAPSRVFVSTDDLLDCLVNPQVTRMVAQLLIQGKSL",
    "output": "May play a role in cellular stress response."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTIMRKNHPLLKLVNSSFIDLPTPSNISSWWNFGSLLGVCLIMQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICMFIHVGRGIYYGSYMLSETWNIGIILLLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAFVLVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTIKDLLGVLLLLMVLMILVLFFPDVLGDPDNYTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALILSILVLALFPLINSSKQHGLVYRPITQTIYWIFIANLLILTWIGGQPVEYPFTTIGQIASIMYFSIIIIFMPMASMIENDILKLHY",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKFTKMHGLGNDYIYVDATSQKIENPNEISRFVSDRHFGIGSDGLVLILPSEIADFKMRMFNSDGSEAEMCGNAIRCVGKFVYDKKMTDKSTITIETLAGIKVLEMTVENDKVVLVKVDMGEPILKAETIPVLSEKHPVIDEEITAKDYCYNFTCVSMGNPHAITYIENVSEFPLEKIGPLFEFHEKFPRKTNVEFVELIDDSTIKMRVWERGAGETLACGTGACAVLVASVLKGYVGRKATVKLLGGDLTIEWNESDNHIYMTGPATTVFEGEIDI",
    "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGKVRHSPKEGYFGEFGGRYSPEILHDALAELETTYKKLKKNKHFKKELEYYRKNYIGRPSPLTYAERLTKVWDGARIWLKREDLNHTGAHKINNTIGQVLIAKAMGKTRIIAETGAGQHGVATATVGAMFQMETVVYMGEEDLRRQELNAIRMRMMGAKVVGVSSGTATLKDATSEAMRDWALNVSNTHYIVGSSIGPHPFPTIVRDFQSVIGIESRKQFKKVNGKLPNAVIACVGGGSNSIGMFYGFLRDKKVKLFGVEAGGYSTEPGHHSATIQFGRTGFLHGTKTLVIQDEFGQIVPAHSVSAGLDYPGVGPEHAYFHKSGRVTYVNVDDDGALDAFLEICQIEGIIPALETAHAFRFAKDLAKSMGKKEDILICLSGRGDKDVAEVARLRKGEFS",
    "output": "The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPRAPKRQRCMPEEDLQSQSETQGLEGAQAPLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPSTPEEVSADDETPNPPQSAQIACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIRNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIVFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE",
    "output": "Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKLVLATNNKGKVKELAELLKPCGYQVVSIGEFPGFTEVEEDGNTFADNAIKKALAAAEFTGELALADDSGLEVDALKGAPGVYSARFAGEPKDDTANNAKLLSLLEGVPQDHRTARFRCVIAIAEPNGRIHTAEGSCEGVILRELKGEGGFGYDPLFYVPEYKQTFAELDMEKKNSISHRGKALKKAMEILNRLYIHQEV",
    "output": "Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTGSIEKPRLIVVMGPTAVGKTAAAIRLAKQWGGEIISADSMQVYRHMDIGTAKPTPDQQCRVPHHLIDIVNPDESFNAACFMERARAVIAELHKRGKKIIVVGGTGLYIRAVLGGLFDGPAADEALRRHYFTILEREGKAGLYGMLKARDRRAAAIIHPNDTTRMIRALEVLDLTGVSIVEQQQEHRFAQRPYRVLKIGLRCSRSVLYERIEARTEEMLAQGFLDEVRQLLDMGFHEGLRPMQALGYRQMVGFLKGELDLDEAVDQLKRETRRYAKRQLTWFGADPEIRWFEPGNEEEILRYAGRFLRGE",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIFSILEHILTHISFSVVSIVLTIYFLTLLVNLDEIIGFFDSLDKGIIITFFGITGLLFTRWIYSGHFPLSNLYESLIFLSWAFSIIHMVSYFNKKQQNHLNAITAPSAIFIQGFATSGLLNKMPQSAILVPALQSQWLMMHVSLMILGYGALLCGSLLSIALLVITFRKVGPTFWKKNIKKNFLLNELFSFDVLYYINERNSILLQQNITFSFSKNYYRYQLIQQLDYWSFRIISLGFIFLTVGILSGAVWANETWGSYWNWDPKETWAFITWTIFAIYLHIKTNRNVRGINSAIVASIGFLLIWICYFGVILLGIGLHSYGSFTSN",
    "output": "Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQAPPPEHCPGVESEQAGQVSACAGCPNQSICSDPNKKREDPGKALVAAALKDVKHKLLILSGKGGVGKSTVTTLLTRYLARSYPDSNFGVLDIDICGPSQPRLMGALGENVHQSGSGWSPVGIDDNVCLMSIGFLLGSVDDAIIWRGPKKNGMIRQFLSEVDWGNLDLLLLDTPPGTSDEHLSVVSYLKDDSSPDSVHAIIVTTPQEVALLDVRKEINFCKKQQIPIVGVIENMSGFQCGHCGHSSEIFPAKTGGAAAMCAEMEVPLLGSLPLDPAIAKACDAGEDITSVKNPTTEALEGICSKIMSSFN",
    "output": "Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSSDSLKKRKPKVNRNEDGKRGRHDEQEGRYYSEEAEVDVRDPREDYQLYKDTCLDLQRLMSEIQDLKNKGGKDSAMEIEEKKVQSCVHFMTLKKLNRLAHIRLKKARDQTHEAKQKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIELVSVEEFYSEAPATISKPEITSTDSHQQTLSRLDWELEQRKRLAEKYKECLASKEKILKEIEIKKEYLNSLQPQLNSIMQASLPVQEYLSMPFDCMHKQYETARHLPPPLYVLFVQASAYSQACDRKLVVTIEGNVEEARALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLCVTLTLKCKEGSTLNLTFYFLMNLNILTVKVKIQPALELSTAISAGDLLNPDLILSCLYQGDDGKTTPNPANRYQFDKIGILSLNDYISELGHPYIWVQTMGGLHFPTDQPQPAVIADNALSASHMEKTINLLRARLLSRLSLHRQFASLEHGSIPVSLECQTLFPAKVISRLTKWNVITYEDYLALPYTKDVIECGLAKETDQYFYLLIERGTAKLNGVVVLNPGYCAVPPVFSLCLNWKGERSSSNDDNIRVMESEVNVYFKELCGPPPGFQLLTNQIQRLCMLLDVYLETERHDNSVEGPHEFPPEKICLRLLRGPSRTKPFKYNYPQGFFSHR",
    "output": "Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway (By similarity).; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAFNMHNRNLLSLMHHSTRELRYLLDLSRDLKRAKYTGTEQQHLKRKNIALIFEKTSTRTRCAFEVAAYDQGANVTYIDPNSSQIGHKESMKDTARVLGRMYDAIEYRGFKQEIVEELAKFAGVPVFNGLTDEYHPTQMLADVLTMREHSDKPLHDISYAYLGDARNNMGNSLLLIGAKLGMDVRIAAPKALWPHDEFVAQCKKFAEESGAKLTLTEDPKEAVKGVDFVHTDVWVSMGEPVEAWGERIKELLPYQVNMEIMKATGNPRAKFMHCLPAFHNSETKVGKQIAEQYPNLANGIEVTEDVFESPYNIAFEQAENRMHTIKAILVSTLADI",
    "output": "Involved in the catabolism of arginine. Catalyzes the phosphorolysis of citrulline, the reverse reaction of the biosynthetic one, yielding ornithine and carbamoyl phosphate which serve to generate ATP from ADP . This catabolic OTCase does not carry out the biosynthetic reaction because of a poor affinity and a marked cooperativity for carbamoyl phosphate ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLMITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ",
    "output": "Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system . UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the effects of CsrA on csrB RNA by BarA-dependent and BarA-independent mechanisms ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIVSFRPTADLVDSIGVDVRSCDLQFRQFGGCSEFAGPISTVRCFQDNALLKSVLSQTSAGGVLVVDGAGSLHTALVGDVIAELAHSNGWAGLIVNGAVRDAAALRGIDIGIKALGTNPRKSTKIGTGERHVEVNLGGVTFVPGEVVYSDDDGIVVV",
    "output": "Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "CEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILLLSKKNAEERLDVFIYNLSRRFGQRGFSPREFRLTMTRGDIGNYLGLTVETISR",
    "output": "It is involved in the activation of genes necessary for anaerobic respiration."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAGQGLPLHVATLLTGLLECLGFAGVLFGWPSLVFVFKNEDYFKDLCGPDAGPIGNATGQADCKAQDERFSLIFTLGSFMNNFMTFPTGYIFDRFKTTVARLIAIFFYTTATLIIAFTSAGSAVLLFLAMPMLTIGGILFLITNLQIGNLFGQHRSTIITLYNGAFDSSSAVFLIIKLLYEKGISLRASFIFISVCSTWHVARTFLLMPRGHIPYPLPPNYSYGLCPGNGTTKEEKETAEHENRELQSKEFLSAKEETPGAGQKQELRSFWSYAFSRRFAWHLVWLSVIQLWHYLFIGTLNSLLTNMAGGDMARVSTYTNAFAFTQFGVLCAPWNGLLMDRLKQKYQKEARKTGSSTLAVALCSTVPSLALTSLLCLGFALCASVPILPLQYLTFILQVISRSFLYGSNAAFLTLAFPSEHFGKLFGLVMALSAVVSLLQFPIFTLIKGSLQNDPFYVNVMFMLAILLTFFHPFLVYRECRTWKESPSAIA",
    "output": "Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine . May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity).; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKKPYQIEIIQKKAPYHPDPTMIFNHLCESRSATLLLETAEVNKKKDLESIMIIDSAIRISSKKNLVKLKPLSINGEEILLALKKRIPKKIEIYEKNKNIILVFPKIEKNLDEDKKLFSLSVFDAFRFMIKIFENKEKKSKAMFFGGLFSYDLSQFFESLPKLKGNQKCSNFCFYLAETLLVLDHQKKTCLIQNSLFTKNANEKKRIKERSIEIEKKLNEKLKSIPKVKITDINLTSNMNNFEYGSIIKKLQKLIQKGEIFQVVPSRKFYLPCPNPLSAYQKLKKSNPSPYMFFMQDKDFTLFGASPESSLKYDEKTRKIELYPIAGTRPRGRTEDGNLDLDLDSRIELEMRTNHKELAEHLMLVDLARNDLARICKPGSRYVSDLVKVDKYSHVMHLVSKVIGELKEGLDALHAYASCMNMGTLTGAPKVRAMQLIAEYEKEKRGSYGGAIGYFTDLGNLDTCITIRSAYVENIATIQAGAGIVYNSIPEDEVNESLNKAQAVINAIKNAHY",
    "output": "Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKQYLDFLRLVKNTGTNKTDRTGIGTTSLFGYQMRFDLSDGFPLITTKRVHLPSVVHELLWFLSGATNIKYLQENGVRIWNEWADKNGDLGPIYGVQWRNWQNVRGESIDQIMQVIEQIKNTPDSRRIIVSAWNVGELENMALPPCHAFFQFYVALGKLSCQLYQRSADVFLGVPFNIASYALLTHMMAQQCDLEVGDFIWSGGDCHIYSNHTKQVEIQLARTPKTLATLKINNKPDSIFDYNFEDFEFINYVFDAYIKATVAI",
    "output": "Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEVAYNLNIDVKKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKEAGADFVGEDDLVQKINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADKAGNVQTIIGKVSFDADKLVENFKAFNDVIAKAKPATAKGTYITNLVLTTTQGPGIKVDANSF",
    "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKRPKEPSGSDGESDGPIDVGQEGQLSQMARPLSTPSSSQMQARKKHRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSSSPGPAGRPAGAMLYHSWVSEITEIGAF",
    "output": "Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPTINQLVRKGRRDKVAKTKTAALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSQVEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKS",
    "output": "With S4 and S5 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAVYNYDVVVLGSGPAGEGAAMNAVKAGRKVAVVDNRPLVGGNCTHLGTIPSKALRHSVRQIMQYNTNPLFRQIGEPRWFSFPDVLKSAEKVISKQVTSRTSYYARNRIDTFFGTASFSDEQSVEVVCLNGMVEKLVANQFVIATGSRPYRPADIDFNHPRIYDSDTILTLSHTPRRMIIYGAGVIGCEYASIFSGLGVLVDLIDNREQLLSFLDDEISDALSYHLRNNNVLIRHNEEYERVEGLENGVILHLKSGKKIKADAFLWSNGRTGNTDKLGLENIGLKANSRGQVQVDEHYRTEIGNIYAAGDVIGWPSLASAAYDQGRSAAGSIVENDSWRFVDDVPTGIYTIPEISSIGKNERELTQAKIPYEVGKAFFKSMARAQISFEPVGMLKILFHRETLEVLGVHCFGYQASEIVHIGQAIMNQKGPANSIKYFVNTTFNYPTMAEAYRVAAFDGLNRLF",
    "output": "Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "METLTSRHEKRALHSQASAISQDREEKIMSQEPLSFKDVAVVFTEEELELLDSTQRQLYQDVMQENFRNLLSVGERNPLGDKNGKDTEYIQDEELRFFSHKELSSCKIWEEVAGELPGSQDCRVNLQGKDFQFSEDAAPHQGWEGASTPCFPIENFLDSLQGDGLIGLENQQFPAWRAIRPIPIQGSWAKAFVNQLGDVQERCKNLDTEDTVYKCNWDDDSFCWISCHVDHRFPEIDKPCGCNKCRKDCIKNSVLHRINPGENGLKSNEYRNGFRDDADLPPHPRVPLKEKLCQYDEFSEGLRHSAHLNRHQRVPTGEKSVKSLERGRGVRQNTHIRNHPRAPVGDMPYRCDVCGKGFRYKSVLLIHQGVHTGRRPYKCEECGKAFGRSSNLLVHQRVHTGEKPYKCSECGKGFSYSSVLQVHQRLHTGEKPYTCSECGKGFCAKSALHKHQHIHPGEKPYSCGECGKGFSCSSHLSSHQKTHTGERPYQCDKCGKGFSHNSYLQAHQRVHMGQHLYKCNVCGKSFSYSSGLLMHQRLHTGEKPYKCECGKSFGRSSDLHIHQRVHTGEKPYKCSECGKGFRRNSDLHSHQRVHTGERPYVCDVCGKGFIYSSDLLIHQRVHTGEKPYKCAECGKGFSYSSGLLIHQRVHTGEKPYRCQECGKGFRCTSSLHKHQRVHTGKKPYTCDQCGKGFSYGSNLRTHQRLHTGEKPYTCCECGKGFRYGSGLLSHKRVHTGEKPYRCHVCGKGYSQSSHLQGHQRVHTGEKPYKCEECGKGFGRNSCLHVHQRVHTGEKPYTCGVCGKGFSYTSGLRNHQRVHLGENPYK",
    "output": "May be involved in transcriptional regulation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQQLELYHIAFLGLAIVLEIIANIFLKMSDGFRKVWLGLLSLLSVLGAFSALAQAVKGIDLSVAYALWGGFGIAATIAAGWILFGQRLNAKGWIGLVLLLAGMVIIKLA",
    "output": "Catalyzes the excretion of spermidine."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNHSEQPFDVKEALLFSQRMAQLSKALWKSIEKDWQQWIKPYNLNINEHHILWIAYQLKGASISEIAKFGVMHVSTAFNFSKKLEERGFLKFSKKLNDKRNTYIELTPKGEETFHKLLEDYDPARTGIVKGAQPLHDIYGKFPEILEMMCIIRNIYGEDFMEIFEKSFSNIEKDFLNERGRVTKKSEELEDSADAAEKAAKANQIV",
    "output": "Negative regulator of protease production and sporulation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAAPESLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVHRIKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAHRGLPPAHNPWEPKPDWACSGSLGSDTGHKDVNGPPRELRPRLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASLSGLRAQDRLIEVNGQNVEGLRHAEVVARIKAQEDEARLLVVDPETDEHFKRLRVVPTEDHVEGPLPSPVTNGTSLAQLNGGSVCSSRSDLPGSEKDNEDGSAWKRDPFQESGLHLSPTAAEAKEKARATRVNKRAPQMDWNRKREIFSNF",
    "output": "Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGHTKRNKTGVLLMNLGTPDAPTTSAVRRYLAEFLSDPRVVEIPRLLWLLILHGIILRIRPAKSAALYKGIWTEAGSPLLAISERQQAKLQGYLDEQQLTDKNGQAVSVHLAMRYGSPSVQQTMLQMHQAGIDNLVVLPLYPQYAAPTTASAFDAIAKTLSQWRYLPSLHFIHTYHDNDDYISALFASIKADFDTNGMPERLLLSYHGMPERNLHLGDPYYCFCMKTTRLVIEKMQQQGLVFDSDFVVTSFQSRFGKAKWLQPYTDVTLEALASEGVRKIAVACPAFSADCLETLEEIEQENREVFIHAGGESFRYISALNDNDDHIVMMANLVKPYL",
    "output": "Catalyzes the ferrous insertion into protoporphyrin IX."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSALTGKHVLVLGLGESGLAMARWCALRGARLRVADSRQTPPGLDTLRADAPLAEIVVGNFGAEVLSGIDLVALSPGVDPRIGIAAEARHRGLPLTGEMSLLAQALDELGVRAQTRILAITGTNGKTTTTALTAALAQAAGLDAVAAGNISPAALDVLMDRLAQGAPLPECWVLELSSFQIETMHALDPEAATVLNVTDDHLDRYAGLDEYAATKAAIFEGRGVQVLNRDDARVAAMALPGRSLIRFGASAPAATDDYGLVEVAGAAWLVRGRERLLALADLPLAGRHNAANTLAALALCEGGLGIAPQRLTGAVVAFRGLPHRVELVAERSDGVRFYDDSKGTNVGATVAALDGMDCPVVLIAGGDGKGQDFSPLREAVVRRARAVVLIGRDAPRIESALQGSAVALEHAPDLDAAVVRASEQAQPGDAVLLSPACASLDMFRNYAHRAEVFIAAARRLPEVRAS",
    "output": "Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSFPGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYNGWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMRSPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNSFSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPDLPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKVLSDFFETAVSLGGDAKQVSNWLQGEIAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVFVHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFTGFLMKATKGQANPQVAQQLLAQELQKLRD",
    "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDAECELYVLELSSFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALTMPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGLQVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETMEQAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG",
    "output": "Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDVLSCSNNTLKGLYDISGVEVGQHFYWQIGGFQVHGQVLITSWVVIAILLGSASIAVRNPQTIPNDSQNFFEYILEFIRDVSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKLVELPHGELAAPTNDINTTVALALLTSVAYFYAGLSKKGLGYFSKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPSVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH",
    "output": "Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQHPHRCPECDGTIRETDTEHVCADCGLVVTDAPIDHGPEWRTFSDDPDHAPERTGAPLTRSRHDRGLSTEIGYSARLTGRKRRKFARLRRQHKRATIPSKADYNRIYGFTEIRRLIGTFGIGTGLRDQACTLFASAQTAGLLHGRTIEGFAAAGVYATCRTNGVTRTLDEIAAAARATRPELTTAYDAMNRDLGLPTGPIDPREYLPRYADALSLPARIERQARELVAALETDGLVAGRNPSGVAAGCLYTAATETDHAVTQSAAAAVADVTPVTLRATYQNLTDA",
    "output": "Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNGNCYKRIVIKLGTSLLTGGTGKLDHERMADLCRQIADLTRLGTEVIIVSSGAIAAGRAKMGLRHIPKDVPFKQVLAAIGQSQLMNYYDQLFSPHGLTVAQGLLTKSDLSDRSGYLNARNTLLALMELGVITIVNENDVVAVDEIQQAKFGDNDNLSAMVANLIEADLLLILTNIRGLYTADPTLHPDARLITEVKEITEELEKLAAGSSNKLGTGGMVTKLEAARLATSSGVNVIIADGHIPDIILKLASGETEGTRFMPSLHKPDSRQRWMMSGLCTRGNICIDDGAVKAIRENQKSLLAAGVQQSEGKFGRGDIVKLSDSRGKRLGYGITNYSSDDVSKIKGLHTDEINTVLAGNQGPEIIHRNNLVVI",
    "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNRRNFIKAASCGALLTGALPSVSHAAAENRPPIPGSLGMLYDSTLCVGCQACVTKCQDINFPERNPQGEQTWSNNDKLSPYTNNIIQVWTSGTGVNKDQEENGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVPKYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRLALKPGSEYHYPRQTLKSGDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYENLDLPKLDDLSTGARSENIQHTLYKGMMLPLAVLAGLTVLVRRNTKNDHHDGGDDHES",
    "output": "Participates in the periplasmic electron-transferring activity of hydrogenase 2 during its catalytic turnover."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQPSTATAAPKEKTSSEKKDNYIIKGVFWDPACVIA",
    "output": "The active factor is excreted into the culture medium by haploid cells of the A mating type and acts on cells of the opposite mating type (type alpha). It mediates the conjugation process between the two types by inhibiting the initiation of DNA synthesis in type alpha cells and synchronizing them with type A."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIRLSKRSVSTLLRSGNQSFRIAAAASTSRSSPSATDVKRSDTESRWYSSLTNGQSKNSGSFAQLNMKTNWFMGYRNESSAAASDSSSQAPPPAEKFEYQAEVSRLMDLIVNSLYSNKEVFLRELISNASDALDKLRYLSVTNPELSKDAPDLDIRIYADKENGIITLTDSGIGMTRQELVDCLGTIAQSGTAKFMKALKDSKDAGGDNNLIGQFGVGFYSAFLVADRVIVSTKSPKSDKQYVWEGEANSSSFTIQEDTDPQSLIPRGTRITLHLKQEAKNFADPERIQKLVKNYSQFVSFPIYTWQEKGYTKEVEVEDDPTETKKDDQDDQTEKKKKTKKVVERYWDWELTNETQPIWLRNPKEVTTAEYNEFYRKAFNEYLDPLASSHFTTEGEVEFRSILYVPPVSPSGKDDIVNQKTKNIRLYVKRVFISDDFDGELFPRYLSFVKGVVDSHDLPLNVSREILQESRIVRIMKKRLVRKAFDMILGISLSENREDYEKFWDNFGKHLKLGCIEDRENHKRIAPLLRFFSSQSENDMISLDEYVENMKPEQKAIYFIASDSITSAKNAPFLEKMLEKGLEVLYLVEPIDEVAVQSLKAYKEKDFVDISKEDLDLGDKNEEKEAAVKKEFGQTCDWIKKRLGDKVASVQISNRLSSSPCVLVSGKFGWSANMERLMKAQSTGDTISLDYMKGRRVFEINPDHSIIKNINAAYNSNPNDEDAMRAIDLMYDAALVSSGFTPDNPAELGGKIYEMMDVALSGKWSSPEVQPQQQQMAHSHDAETFEAEVVEPVEVDGKK",
    "output": "Molecular chaperone which stabilizes unfolding protein intermediates and functions as a folding molecular chaperone that assists the non-covalent folding of proteins in an ATP-dependent manner."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRLLQCGNEIYSAIKDLQSKAPDKNIVIFTHNHCLTYIAKNKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH",
    "output": "Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVNAAVRAADAAFAEWGQTTPKARAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINVLFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISHTAPSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGSPDDESTELGPLSSLAHLERVSKAVEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTLFDNEEQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVKH",
    "output": "Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNHFPKLLSSQIGFDVAQTMLENFDRHYRIFREAAVEAKTLYEHGDWHGLQRLARERITSYDDRVKECVEVLEDEYDAENIDDEVWQQIKLHYIGLLTSHRQPECAETFFNSVCCKILHRSYFSNDFIFVRPAISTEYLENDEPAAKPTYRAYYPGTDGLATTLERIVTNFQLEPAFDDLPRDIGCVMQAIHDEFGHFDEAPNFQIHVLSSLFFRNKSAYIVGRIINADRVLPFAVPIRHVRPGVLSLDTVLLRRDQLMIIFGFSHSYFLVDMGVPSAYVDFLCTIMPGKPKAEIYTSVGLQKQGKNLFYRDLLHHLSHSSDRFIIAPGIKGLVMLVFTLPSFPYVFKIIKDHFPPPKETTRAQIMEKYQLVKRHDRLGRMADTLEYSSVALPIARLDHALVRELEKEVPSLLEYEDGNLVIEHLYIERRMTPLNLYLQNGSDSDVEHGVKEYGNAVKELMKANIFPGDMLYKNFGVTRHGRVVFYDYDEIEYLTDCNVRRVPPPRNEEDELSGEPWYTVGPHDIFPETYGPFLLGDPRVRDVFMKHHADFFDPALWQASKDKLIQGELPDFYPYDTALRFCTRYPARFGATDQNDGAGDAQRAA",
    "output": "Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVSTTLSVSRMTFVWRAARPSLLNHSLRKMSYQEGKPEPAKQALKKSKLPLGRFDSLEDSPEEREPLQKFPDDVNPVTKEKGGPKGPEPTRYGDWERKGRCIDF",
    "output": "Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol . Binds to the flavoprotein subunit Sdha in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit Sdhb into the SDH catalytic dimer (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAAKIIDGKTIAQQVRSEVAQKVQARVAAGLRAPGLAVVLVGSNPASQIYVASKRKACDEVGFVSRSYDLPETTSEAELLALIDTLNADNTIDGILVQLPLPAGIDNVKVLERIAPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTYGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKDLRHHVEHADLLIVAVGKPGFIPGEWIKEGAIVIDVGINRLENGKVVGDVVFDEAAARASYITPVPGGVGPMTVATLIENTLQACIEYHDPQGK",
    "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN",
    "output": "One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization (By similarity). Probably involved in PSII assembly . May be involved in PSII dimerization ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTQKLQKIVLPPVYGPADFEARVYACWEQRQAFSPRARGSGTSDSEGCDGHSRQIEGGARTFVIAIPPPNITGVLHMGHCLNTVLQDIVIRYQRMAGACTLWIPGTDHAGIATQHVVERALRKEGIHKREVTREQFVARTQQIKDSHQDTIRMQLRKMGASCDWTCERFTLDAGMSASVREAFVTLYERGLLYRSMYLVNWCPRCGTALSDDEVFHQEKDGALYYVRYPLLPRTEEEGNGVPPPLGTAQVGETIIIATTRPETILADVAVAVHPDDARYQSLIGRKVCVPMVNRIVPIIADSYVAQDFGTGMVKITPAHDPNDWDIGTRHSLEAINMLNPDGSLNDQVPAAYRGLSCAQARIQIVADLQAHGLLSREERIVHSVGVCYRCEAVIEPYLSLQWFVKMKPLASQALAAWKRADVQFHPKKWENTYVRWLEHIRDWCISRQLWWGHRIPVWYCAQCAQQTVSRVDVQRCAHCGSADITQDPDVLDTWFSSWLWPFSTLGWPQETQKLRAFYPTSAVITAYDIIFFWVARMIMAGLEFTQTVPFRDVYLHGLVRDKQGRKMSKSLNNGVDPLHIIRTYGADALRFTLAFMCAQGQDVLIEMDSFKMGSRFANKVWNASRYILGNLEGRRVYAIAHVSLTELDRWIFHTFNETVQQVRTALEAYRFNDAAQAVYEFFWNSFCDWYVEASKCSFQKPDEQEKDRAASVLCTLLEETLRLLHPFLPFVTEEIYRSLSPSVHDTTQAIPSGAHALLMCAPYPVYVPSRVDARACAHIGAVQEIVRAVRTLRAACGIDPQKAVSVRLRPSSPAQDANAAAQVSCVHDPGAVARTYEELICVLAGISSLVYLESDAPKPQVAVATAGTGFELFLVTTEGIDRTMLCARLQKAWQKARQKVQQVERKLADAQFCTHAPEEVVTAERKKLAEARATCHTLAGYLADMNGKPGPLSDSD",
    "output": "Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEEIKVNVELREKAGVKGVLSAIRAEKKVPAVIYGGQKEPISVSITEKDLKAILKAGSNSVVTLSTPAGKETAIIKEVQYHVVKDTPNHVDFQRISLKEKIDVVVPLKLTGESADVKIYGALINQVLREVAIRALPTAIPHEIAVDISALTIHKAIHISDLSLSKDIEVLGDPERAIVHLMVPREEETVAAPADTAVQPESSSTKGKKDEDGALAKDKK",
    "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKPPGICMDESVSLSHSGSAPDVPAVSVIVKNTSRQESFEAEKDHITPSLLHNGFRGSDLPPDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIKPKHSDSYFPPPLGCGAVGGPVLEALAKFPVPELHMFDHFCKKEPKPEPLPLGSQQEHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPPRQRLKPAHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPLEATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGARKGDESMTKASDSSSPSCSSGPRVPKGAAPGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPHSVAASVTAKSSVQRRSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSPKHGLTSGSASPPPPALPLYPDPVRLIRYSIKCLECHKQMRDYMVLAAHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKVGYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQPHRPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLLFVQKPELMQHVKSTHGVPRNVDELSSLQSSADTSSSRPGSRVPTEPPATSVAARSSSLPSGRWGRPEAHRRVEARPRLRNTGWTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLSQTSKVKPPGGHSPQVNHLKRPVSGVGDAPGTSNGATVSSTKRHKSLFQCAKCSFATDSGLEFQSHIPQHQVDSSTAQCLLCGLCYTSASSLSRHLFIVHKVRDQEEEEEEEAAAAEMAVEVAEPEEGSGEEVPMETRENGLEECAGEPLSADPEARRLLGPAPEDDGGHNDHSQPQASQDQDSHTLSPQV",
    "output": "May be involved in transcriptional regulation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLERLNFIENKYEELSNKISDPSVMANQKEWQKLCKEHADLEIIVNTYREYKKAQEDLESDKEMLKEESDKELREMAQEEIKELTLKLEDLERELTILLLPKDPNDDKDVFIEIRAGAGGEEAALFASNLLRMYTRYAERKNWKVETISLNATDIGGFKEVTVAVKGKGAYSRLKYESGVHRVQRVPDTESSGRIHTSTATVAVLPEVDDVDININANDLRIDVYRASGHGGQCVNTTDSAVRITHLPTGLVVTCQDEKSQLKNKEKAMKVLKARLFEAAEAERAASIAEDRKSQVGTGDRSERIRTYNYPQGRITDHRIGLTLYKLETFLDGDIDEAIEALVTEDQAEKMKDLGRVN",
    "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKDIKFSEEARRSMLRGVDTLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPMGLRKGIEKAVVAAVEELKTISKPIEGKSSIAQVAAISAADEEVGQLIAEAMERVGNDGVITLEESKGFTTELDVVEGMQFDRGYASPYMITDSDKMEAVLDNPYILITDKKISNIQEILPVLEQVVQQGKPLLIIAEDVEGEALATLVVNKLRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGEVITEELGRDLKSATVESLGRAGKVVVTKENTTVVEGVGSTEQIEARIGQIRAQLEETTSEFDREKLQERLAKLVGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTSLMNVYTKVASIVAEGDEATGINIVLRALEEPVRQIAINAGLEGSVVVERLKGEKVGVGFNAATGEWVNMLETGIVDPAKVTRSALQNAASVAAMFLTTEAVVADKPEPNAPAMPDMGGMGMGGMGGMM",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPHHDQLHRYLFDNLAVRGELVNASATYARILENHDYPAAVRALLGELLVATTLLTATLKFDGDITVQLQGDGPLKLAVINGNHRQEMRGVARLQGDIADGSSLKHMLGNGIMVITITPKEGERYQGVVALEGDTLSNCLEAYFMQSEQLPTRLFMFTGEQDGQPAAAGMLLQILPTQPNNVDDLTHLSHLTTTVTPQELFTLPANEVLYRLYNQEQVTLFEPQPIAFLCGCSRGRSASALMSLPPQQLEELLAERGSIDIHCDYCGSHYLFDRVDIDALRAGAQPDEAGQLH",
    "output": "Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSEDFYDVLGVSRNADGDDIKQAYRKKAAKYHPDVSDDPNAEEKFKKIKKAKEVLTDGEKRQMYDQLGHDRFQQAEKRGGVGGGGNSSGGSARGDPFGGMGGQGSPFGDIFEQFFGGGQGQRRQGNRPRQGQNLQTRVQLDLEEVYTGVEKQFTVRRPEKCPDCNGRGHPSDADVRTCPQCNGQGQTTTVRETALGRVQQTQTCPRCDGSGEMYTQTCSTCNGDGVTRQEATLSVDIPAGIRDGQTLRMEREGAPGDNGGPRGDLLIDVSVRDHPDFERDGDDLYYRLAISFPQAVFGSTVEVPTVNGETTLDISAGTQSGEEFRIRNEGIPHLRGRGTGDLYVQVQIVTPENLSQKQREALEAFAEAGGESVDVSQGFFEKIKSSF",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIAETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE",
    "output": "Muscle contraction."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVIKSNDVREPFNEDKLRSGMLRALEKRPVSADDVEMALNHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKDFGEEIARLQD",
    "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKYKRIVFKVGTSSITHSDGSLSRGKIQTITCQLAALHHAGHELVLVSSGAVAAGFGALGFKKRPVKIADKQASAAVGQGLLMEEYTANLSSDGIVSAQILLSRADFADKRRYQNAGGALSVLLQRRAVPIINENDTVSVEELKIGDNDTLSAQVAAMIQADLLVLLTDIDGLYTGNPNSNPDAVRLDKIEHINHEIIEMAGGSGSANGTGGMLTKIKAATIAAESGVPVYICSSLKPDALAEAAEHQADGSFFVPRAKGLRTQKQWLAFYSESRGSVYVDEGAEHALSEQGKSLLMSGIAGIEGHFSRMDTVTVYSKATKQPLGKGRVLFGSAAAEDLLKSRKAKGVFIHRDDWISITPEIRLLLTEF",
    "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "METATLVAIFISCSLVSFTGYALYTAFGQPSKELRDPFEEHED",
    "output": "May play a role in photosystem I and II biogenesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG",
    "output": "Involved in the binding of tRNA to the ribosomes."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV",
    "output": "Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSMFCFQCQETAKGTGCILSGVCGKTPEVANMQDLLLFVVRGIAVYNQALRKDGRSSARADKFIFDALFTTITNANFDKHSIIEKIKKGLELKKDLSNQVTIEHAPDECTWYGDETEFEEKAQTVGVLRTSDEDIRSLKELVHYGIKGMAAYVEHAYNLGYENPEIFAFMQYALAELTREDITVDELITLTLATGNHGVQAMAQLDTANTSHYGNPEISEVNIGVRNNPGILVSGHDLKDIEELLQQTEGTGIDIYTHSEMLPAHYYPQLKKYKHLAGNYGNAWWKQKEEFESFNGPILFTTNCIVPPRPNATYKDRIYTTGATGLEGATYIPERKDGKQKDFSVIIEHARRCQPPVAIESGKIVGGFAHAQVIALADKVVEAVKSGAIRKFFVMAGCDGRMKSRSYYTEFAEKLPADTVILTAGCAKYRYNKLPLGDINGIPRVLDAGQCNDSYSLAIIAMKLQEVFGLKDINDLPIVYNIAWYEQKAVIVLLALLALGVKKIHLGPTLPAFLSPNVKQVLIDNFGIGGISTADEDIAKFLA",
    "output": "Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSRIGKRPIPIPNKVTVDIDGATVTVKGPKGTLQRTLPTAVAINKDGETLLVTRQDDSRTARERHGLCRTLVANMVEGVATGFQKRLDIQGVGYRAQAQGSKLVLNVGYSKPVEMEMPDGVSVAVENSTQVIVSGIDKEAVGNTAAKIREVRPPEPYKGKGIRYLGEVVRRKVGKAGGKGAKGGKGGKK",
    "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKYQQLENLESGWKWKYLVKKHREGELITRYVEASAAQEAVNLLLALENEPVRVNVWIDRHMNPALLNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFMVWQRLAGLAQRRGKTLSETIVQLIEDAEHKEKYATQMTTLKQDLQALLGKK",
    "output": "Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "ASFDEAPPGNSKAGEKIFKTKCAQCHTVDKGAGHKQGPNLNGLFGRQSGTTAGYSYSAANKNKAVEWEEKTLYDYLLNPKKYIPGTKMVFPGLKKPQDRADLIAYLKEATA",
    "output": "Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALNLQDKQAIVAEVSEVAK",
    "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKKGTVLNSEISSVISRLGHTDTLVVCDAGLPIPNSTARIDMALTQGVPSFMQVVDVVTREMQVEAAILATEIKQQNPQLHETLLTHLEQLQQHQGNTIKISYTTHEQFKKLTADSQAVIRSGECSPYANVILCAGVTF",
    "output": "Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQIQLPMFQNSRVVVVGDVMLDRYWYGATSRISPEAPVPVVKVEQLEDRPGGAANVALNIAALGSAAVILGVTGKDEAAQSLAARMESAGILADFQEHETLPTITKLRVISRHQQLIRMDFEESFAGVPQEQLEKKVAGQLAGAGALVLSDYGKGALRDPQAFIQLARSKQIPVLVDPKGSDFEKYRGATLITPNLSEFEAVVGHCTSEAELVQRGLKLVEELELEALLVTRSEQGMTLLRAGRSELHLPAQAKEVFDVTGAGDTVISVLAAALAAGSEMGQAVALANIAAGIVVGKLGTASVSAPELRRAVQQEQGAGRGAMTVEQLKVALDDARAHGEKIVFTNGCFDIIHAGHVGYLDQARKLGDRLVVAINSDASVSRLKGPARPINPLERRMAVLAGLEAVDWVTWYEDDTPERLLEILKPDILVKGGDYSKEQVVGWEIVEGYGGEVRALDFLDNCSTTAIVEKIRKDQVK",
    "output": "Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "XFEGRGGFGGRGGGDRGGRGXGGFGGG",
    "output": "S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSFKFEAEVRSAQGKGASRRLRHNGQVPAIIYGGKAEAVSIILDHDKVNNAQAHDAFYNEVLTIVVAGKEEQVKVQAIQRHPTKPKLVHLDFKRI",
    "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAEFKLYLPVQNKAKQ",
    "output": "Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility (By similarity). Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIHCKVQQWSPQYLRLPATGYEELTLTLNTSMLARMPEEEDQLFLVVGDSPSSTYVDWGEDCNSTRYPSYDHCTHKILYLGASAGTTRSKRLSATIGIRLSKGTGSNNVLGTPMYLLYNEMKTRIIESSK",
    "output": "S-adenosyl-L-methionine-dependent protein-cysteine S-methyltransferase with broad substrate specificity. Methylates trehalose-6-phosphate synthase (TPS), enhancing its enzymatic activity and promoting trehalose synthesis upon entry of cells into stationary phase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEPPAIPHITEGFYPLPEIVETFSHHVLQELVSLAEVLPSMSNVEKKKKILDWLLRSRAFTMRLLVLARWVHLSPSVHRCIDVVAFLQGQKFCFQNLVHVLQDIRYQLSFARLRNSDLVTALDILSTGTSLRLANAPTSKLYMLSESPLSTKQILQTLHALNMLIRIRLSLYEIIPTPFQHFTIANGRCTFTVPNEFSVSLTTNSQDPKSTGISFQWIVVDFQFHLPDFSSTPAKYRVFIELHLNEEIAAAFVLQKPILPLIYNILHKFCLYQRLNLLSQQTFQLSRESWLGHLRGVYDEKPPRLRLYYWPQLNVKKEGKPGKIGHYIHIFVNTQPISAFERTLSSKRSSCEYDHFLLLVEWHHDGIVEHVPLDDHMDAQHLLLLITQKHAQLILEQIRKELHPNIFSEHVGGGLKIHVFDNEIIVKVNSVTGRLVLSSSASPLSPPRHLRAAEKNIALNTQPPAQILNRLYFFCIQTQLLEVAQCAELHAVQGYYSFPYLTFSKGKWRKDGDSLWVLAYNVESNSWSVRLLNAAGQTLYTQDVHTTKGTLSIESFSRLSYLLEVQILLFNVQTACQARGMPFEYLPIPPKALIEDDFTTYVQTGCLCIMMPSSNEDMLPVVFVRAHDGQLIFDSRIKGKLPYQSETETEKNCYIDWRTGRITIRVQNFSSFEKTWIGLLKLVALSKTSAFNVDCITLKHVDFTYLDDEKFRATIHDDNTFTLHFFNRHSPFHLISQFLQDTFSDGPSAIQPLRVIMDRTRGVLVAQELGYVVLARSLRQYRIILSKNHGIQVLLNRHGCILQDLSYLSADSRYLEGTQTLTSQWEPCSWLNTVWEGDLGDDELNGQIEAAPEMHLIKMNKTADLTAILKRILAISRKK",
    "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVSSILKFVILIHSTFHSTFAQNLPDTTVAPKTKRTIKIGIAAAQRTQTSSIGWSVCGGAVPMAIERLREFGYVKDFDFEFIVDYTECDQGSVVRAGIEFIKTHKVDVIIGPPCAQALRVMSFLAENYKKPVLGWGFVSDTDLSDVIRFPYLTTVIPNSLMLGYAASKMLTVYNWGRVAMLYYYSDIKYCSGVMNDVEATFNNPSTPNVNIVIKAEIYLNDNETTDIVFQSVKSRARIIFWCTQTAIEKRDYLIKIATHDMIGDEYVHIMLSMRNIAFGAQTSLGKPTFSQSGLTPIWESFTEGTDDFEKMVKQAATRMFVLDVNSEVADKKYLDYLQKNIMKAVQSPPMNCSTVECMTANTTIMGGYARQLFDVVYLYGVALTNTNSTDPAVYDDVDVIVPQFVTSFQGMTGKVVISPNLTRMPIFQLYGLNSDYEQVALAEFTYIDPIMNVTLSYKEEGGAVWYFYGNSRPLDIPICGFLGKFCPISFWEQYMILAIVSISVIVLMVIIMIIGCLCVISAKHAEQARTNAEWQVPFVNLMESEKQIRSNATSRRSLQSAPSISTGHSGVTTVSDFCENYTMMMYEKEMVLTAKYQYTHLTKADKERFVKMRKLDHENINRFIGLSIDSAHFIAVTKLCSRGSLQDILSRGNFSMDYFFMFCIIRDVAKGLEYLHKTFLRLHGNLRSATCLVNDSWQVKLAEYGMDNLVEEQTPPKKRLLWVAPEVLRGSLSVSQMEPSADIYSFAIIASEILTKKEAWDILDRKEDCEALIALVKDCWAEVPEDRPTAENICSQMKGLVSKQKTNLMDHVFNMLEEYTSTLEEEIEERTKELTLEKKKADILLSRMLPKQVAERLKAGQTVEPEGFDSVTVFFSDVVKFTILASKCSPFQTVNLLNDLYSNFDTIIEQHGVYKVESIGDGYLCVSGLPTRNGYAHIKQIVDMSLKFMEYCRSFKIPHLPRENVELRIGVNSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGKPSLIHLTSDAHLLLLTHYPNHYDTSSRGEVIIKGKGVMETFWVHGRIDDIAEPTELRSICKPSTVANERWITPPAPKPEIRSVSSHGSRPPSVYDPLQDHRKFKMDTLKVAN",
    "output": "Guanylate cyclase involved in the production of the second messenger cGMP (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKLHELKPAEGSRKVRNRVGRGIGSGNGKTAGKGHKGQNARSGGGVRLGFEGGQTPLFRRLPKRGFTNINRKEFAIVNLSTLNRFEDGTEVTPELLLETGVISKLNDGVKILASGAVEKKLTVKAHKFSSSAKEAIEAAGGSVEVI",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRVLTGLQPSGDLHIGNYFGAIKQMVDAQEKSQMFMFIANYHAMTSSQDGEKLKQNSLKAAAAFLSLGIDPQKSVFWLQSDVKEVMELYWILSQFTPMGLLERAHSYKDKVAKGLSASHGLFSYPVLMAADILLFDTRIVPVGKDQIQHVEIARDIALKVNNEWGEIFTLPEARVNEEVAVVVGTDGAKMSKSYQNTIDIFSSEKTLKKQISSIVTDSTALEDPKDHENCNIFKIAKLFLDESGQKELQIRYEKGGEGYGHFKIYLNELVNAYFKEAREKYNELLEKPSHLKEILDFGATKARKIAQEKMQKIYEKIGL",
    "output": "Catalyzes the attachment of tryptophan to tRNA(Trp)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPSQLEALRRHTVVVADTGDFEAMRALRPTDATTNPSLILKAVQQEAYRPLLVQTARAHQGASPAEITDRLLVAFGRQILDIVPGRVSTEVDARLSFDTRATVERARGLIALYQAAGVPRERVLIKIASTWEGIQAARVLQAEGIRCNLTLLFCLPQAAACADAGVQLISPFVGRIYDWHKKNAGAEWVEDARRGANDPGVQSVSRIYRYYKRFGIETEIMGASFRNVDQILALAGCDLLTISPELLTRLSQTEGEVPAALSPQAGHDDADAVRLDGGEVAFRTQLNEDAMASEKLSEGIRLFVADARKLDALIESHGAA",
    "output": "Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGEEQSTVSGSGGARASGGGSAGQPESPRPRGDRVRTAGPRAAASSSRPNGGGGGRDPGCVDASVQEPASNRAPAGQPARLPLSGPLDPQSLELQLEREAEGAGPREAPPGQQPPDGLLLDVLAQRHPPPAKPQVLCSVYCVESDLPEAPSAESPSPSESPPQAPLGPIPASPPPSFPSSPLSLPADPLSPDGGSIELEFYLAPEPFSVPGLLGAPPYSGLGGVGDPYAPLMVLMCRVCLEDKPIKPLPCCKKAVCEECLKIYLSSQVQLGQVEIKCPVTECFEFLEETTVVYNLTHEDSIKYKYFLELGRIDSSTKPCPQCKHFTTFKKKGHIPTPSRSESRYKIQCPTCQLIWCFKCHSPWHEGVNCKEYKKGDKLLRHWASEIEHGQRNAQKCPKCKIHIQRTEGCDHMTCSQCNTNFCYRCGERYRQLRFFGDHTSNLSIFGCKYRYLPERPHLRRLVRGSVCAGKLFIAPLILVLGLALGAIAVVIGLFVFPIYCLCKKQRKRSRTGMHW",
    "output": "E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MERQNIRIRLKAFDHRALDMSAKEIVNTAKRTGAEVRGPVPLPTRIERFTVNRSPHIDKKSREQFEIRTHTRILDIVDPTPQTVDALMKLDLSSGVGIEIKLEGAR",
    "output": "Involved in the binding of tRNA to the ribosomes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAIKKITIVGAGRVGEATAQFLVKNELCRELVLLDAQEGVAQGAALDIQQSAPLFDFDARVTGSTNYELIADSDLVVITAGKPRKPGMSRSDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPVDVLTYHAWRHCGWDRARVFGQAGVLDSARMASFIAGETGLSVKDISAMVLGGHGDTMLPLIRYTTISGIPLTHFLDQQVIEKIIERTRHGGFEILRLRQTSSAYDAPAAAIAGMVDAIRHNRKRILPCVAILQGEYGENEVAMGVPSVLGGDGLERIVELPLTEEEQEQFKHSVEAIRTDLAHLARA",
    "output": "Catalyzes the reversible oxidation of malate to oxaloacetate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGNCNGASKSNQPDSSRVTQPAAEFRRVAHSSLYGRYNCKCCWFADTNLITCNDHYLCLRCHQVMLRNSDLCNICWKPLPTTITVPVEPTAPPP",
    "output": "Plays a crucial role in virion assembly and budding. Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L. Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z. Also selectively represses protein production by associating with host eIF4E."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAWSQVEISKPHLAYAIIGGFTSLFMLCSLIIKEKLFLGEATMATATGLIFGPYVAKLFVPTSWGNTDYITEELARVLLVVEVFAAGAELPRAYMLRHWRSMFVMLLPVMIFGWLVSTGFMYALIPRLSFLESLAIAACITATDPVLASSIVGKGKFARRVPGHLRNMLLAESGCNDGMAIPFLYLAIYLIIEKPARHAGRDWVCIIILYECTFGCVLGAIIGVIARKMIKFSERRGLMDRESFLVFYFVLALFCGGIGTIIGVDDLLVSFCAGAAFSWDSWFSKKTEESHVSNVIDLLLNLSFFVYVGAIMPWPQFHMPHMDLSVWRLVVLAICILIARRIPAVLLFKSFVPDIINWREALFAGHFGPIGVGALYTCLVARAELEVHSTVPEPNDAIENPEIPNWYCIQVMWPVVCFLVLSSIIVHGSSIAFFMLGKRINTLALSFTRTRDSHFAFNLPRVRQGQSLPIKRVDALRSSANSIASSIRRRHPVNIQEDEDADISTVSLPEAAHLREERAESPRGGHYDAEEFPSEDYESRQPRRSNEEDREEEMNPGDETYLIGEDLVVEDSQGNIISHTSSRDANGPSIDEKLAQGDPKAKSFGRKFRSFLRRSYDTFQRNLHEPDDERQREPTLGHIESSIENHRPRYSRQNSESHLRENSVERRRREQVLTNIGDSESEDDNIPRPGIVPFYNENNESSSDTRNGLLSDNVSESRSRRPSRAPSAAVSSEGSPVEEDNEAQHRPNIRFLELTRAWE",
    "output": "Sodium export from cell, takes up external protons in exchange for internal sodium ions."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "METQNTGTEDGFTPVTHRGGRRAKKRQAEQSSAAGQDGDAGRMDTEEARPAKRPVFPPLSGDQLLTGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKDTKDVSALTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF",
    "output": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDKVSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYERIEDKLRALGANIERVKGE",
    "output": "Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFDKTQTIADFDPDVWQAIVDEGVRQEEHIELIASENYTSPLVMVAQGSKLTNKYAEGYPSKRYYGGCEYVDKVEELAIERAKALFGADYANVQPHSGSQANSAVYAALCAPGDTVLGMSLDHGGHLTHGAKVNFSGKMYNAVQYGLNPETGLVDYEEIAALAREHKPKMIVAGFSAYSQVLDWQKFRDIADEVGAYLMVDMAHVAGLVAAGVYPSPVQIADVTTTTTHKTLRGPRGGIILAKANPEIEKKLNSAVFPGGQGGPLMHVIAGKAISFKEAMSDEYKAYQQRVVDNAKTMAATFIKRGFKIVSGGTENHLMLVDLIGKDYSGKDADAALGAANITVNKNAVPNDPRSPFVTSGLRVGTPAITTRGFGETEVVDLTNWMCDVLESLEAGNSEAVIADVKAKVLDVCGKFPVYGSN",
    "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTQPNEFKHISVLLDECIEALAIKPNGIYIDATFGRGGHSAHILDALGEKGRLIAFDRDPQAIKAAERFADDKRFSIIHSPFGDMAEEIEALGLTGKIDGVLMDLGVSSPQLDDAERGFSFLRDGPLDMRMDTSRGQSAADWLASAEEQDITQVIKEFGEEKFGKRIAHAIVNTRKDTPITRTAQLAKIIDEAVPVKDKFKHPATRAFQGIRIYINAELEQLRVGLKAATQVLAKEGRLAVISFHSLEDRLVKRFIKDQSKGKVVPHNLPITQAEIDADKVLKALGKAIKPSEQEIANNVRSRSSVLRVAEKL",
    "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNSGYNPGNANHITSHSNRTKNGVPTIPQPALMASNAILTIGPYKHRKDLIRESVLTKYQIIGYIAAGTYGKVYKAKSKTNGNSNSNSALMNDNVISIGNGQKEAGLQKTNNESMEDKNQLFAIKKFKSDNHSNKNNHDINGNEVIHYTGISQSAIREMSLCRELSNKNITKVVDILLENKSIYMVFEYCEHDLLQIIQYHSHPDVKPIPDFTIKSITWQILNGVTFLHKNWIFHRDLKPANIMVSSSGVVKIGDLGLARKFNNPLQSLYTGDKVVVTIWYRAPELLLGARHYTPSIDLWAVGCILAELLSLRPIFKGEEAKIDMNNKKSVPFQKNQLQKIVEVLGTPTTKNWPTITKYPEYSAFQQHFSNTYPPNLISWYKLIGRTSKQCLNLLRCLLEYDPTIRITADDALTHAFFLELPKMSENSFEGLSQKYPKRRIYTHENDIVSNSQHVNNKRHGYDDNMTRKRQR",
    "output": "Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE",
    "output": "Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTSPSPTARRTRLRRRTALALAAAATAALTLSACGTDTKANTPATRAGSGNAAAAKADTVALLDDTTLAVPGDKPSALFFFSVGCGECAGGAKSLDKAAQAFDKAGKKANFLAVDMDPNESKQTIMQFLDYIKAPALPATIDKGAALSQRYQVAALSTLIVVAPQGKVTYRATDPSADQIQDALKKAGA",
    "output": "Probable mercury binding protein."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKIINILFCLFLLMLNGCNSNDTNNSQTKSRQKRDLTQKEATQEKPKSKEELLREKLNDNQKTHLDWLKEALGNDGEFNKFLGYDESKIKSALDHIKSELDSCTGDKVENKNTFKQVVQEALKGGIDGFENTASSTCKNS",
    "output": "An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein . The Mlp proteins probably undergo intragenic recombination, generating new alleles (Probable)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEKKVQKLHDKKNIALVAHDNMKDPLCKWAKKHSFKLSAHQLYATGTTGHKLEEATGLSIRKCVSGPLGGDQQIGAKISEGEIDILIFFWDPFEPMPHDPDVKALLRIAAVWNIPVACNPASADFIISSQYINEEYERLVPDYDAYIAKRLG",
    "output": "Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTALPATSIAAPSLDDLDALNAHLETLRADERVAWALQHGPQQAALSSSFGAQSAVTLHLLTQQRPDIPVILIDTGYLFPETYRFADALTERLSLNLQVYRPLVSRAWMEARHGRLWEQGMVGIDQYNNLRKVEPMRRALDELNVGTWFTGLRRSQSGGRAQTPIVQKRGDRYKISPIADWTDRDVWQYLQAHALPYHPLWEQGYVSIGDFHTTRRWEPGMREEDTRFFGLKRECGIHEDI",
    "output": "Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSDVDADEARKMAERERKKEEVRKRLEEASRMKKAKKGFLTPERKKKLRKLLMMKAAEDLKQQQMLKEQERQRILQERIIPLPDLDNEDDLEAVYDEIRERLIDLESENYDVSYIVRQKDFEINELTIAVNDLRGKFVKPTLKKVSKTEGKFDKLKKKEATKVDFRAQLKVVDKNEFALDEEDTEKKEKAAWAK",
    "output": "Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to muscle actomyosin ATPase activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIGLADYLILGALLFSLGVAGIFINRKNLLVLLMCIELILLAVNMNFIAFSAYLQDLAGQVFVFFILTVAAAEAAIGLAIVVALFRNRGSINVGDLDSMKG",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTASPSKLAQLRDLSVVVADTGDYDAIKRLKPVDCTTNPTLVKKALDLPVYADLIERELAWGRAHGGEDRNSTINEVADRLTVGVGTMLSELVPGRVSTEVDADLAHDTQATIAKARKFIAMYAERGVSKDKILIKIAATWEGIEAARQLQQEGIDCNLTLIFNRSQALACAEAGVFLISPFVGRILDFFVAKGQTPASIDEDPGVVFVRGVYDEFKRRGSSTVVMGASFRSTAQIEALAGCDRLTISPDLLEKLDADHGDLPRKLSPLNADNAAITPINSDSFATDLAADDMATEKLASGIDTFAKDLEALRKTIADKLAG",
    "output": "Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTMGDMKTPDFDDLLAAFDIPDMVDPKAAIESGHDDHESHIKQNAHVDDDSHTPSSSDVGVSVIVKNVRNIDSSEGVEKDGHNPTGNGLHNGFLTASSLDSYGKDGAKSLKGDTPASEVTLKDPAFSQFSPISSAEEFEDDEKIEVDDPPDKEEARAGFRSNVLTGSAPQQDFDKLKALGGENSSKTGVSTSGHTDKNKVKREAESNSITLSVYEPFKVRKAEDKLKENSEKMLESRVLDGKPSSEKSDSGIAAAASSKTKPSSKLSSCIAAIAALSAKKAASDSCKEPVANSREASPLPKEVNDSPKAADKSPESQNLIDGTKKASLKPSDSPRSVSSENSSKGSPSSPVGSTPAIPKVRIKTIKTSSGEIKRTVTRVLPEVDLDSGKKPSEQAASVMASVTSLLSSSASATVLSSPPRAPLQTAMVTSAVSSAELTPKQVTIKPVATAFLPVSAVKTAGSQVINLKLANNTTVKATVISAASVQSASSAIIKAANAIQQQTVVVPASSLANAKLVPKTVHLANLNLLPQGAQATSELRQVLTKPQQQIKQAIINAAASQPPKKVSRVQVVSSLQSSVVEAFNKVLSSVNPVPVYTPNLSPPANAGITLPMRGYKCLECGDAFALEKSLSQHYDRRSVRIEVTCNHCTKNLVFYNKCSLLSHARGHKEKGVVMQCSHLILKPVPADQMIVPPSSNTAASTLQSSVGAATHTVPKVQPGIAGAVISAPASTPMSPAMPLDEDPSKLCRHSLKCLECNEVFQDEPSLATHFQHAADTSGQQMKKHPCRQCDKSFSSSHSLCRHNRIKHKGIRKVYACSHCPDSRRTFTKRLMLERHIQLMHGIKDPDVKELSDDAGDVTNDEEEEAEIKEDAKVPSPKRKLEEPVLEFRPPRGAITQPLKKLKINVFKVHKCAVCGFTTENLLQFHEHIPQHRSDGSSHQCRECGLCYTSHGSLARHLFIVHKLKEPQPVSKQNGAGEDSQQENKPSPEDEAAEGAASDRKCKVCAKTFETEAALNTHMRTHGMAFIKSKRMSSAEK",
    "output": "May be involved in transcriptional regulation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MWQIRASAGCHSSPGKDKEVTLENTMNFSDIYHSDEEYFRKLKDLRAAHAEAMVKLEKMYQDKLTMKDIQAALVGDDSSSSASEKSCSHPALSATSLSEPDLDRSSSLSTTTDELPDLEKKTPGEIGTRSYAKELINNMWNDFSVEDYTQYDSDLQTAKKNRKKPKAWTPRITVPVPFEMTVREQKRREKASDAQETREKMLKRNEDDAECKKKFRANPVPSRLLLPLYEDLVKQNEERRKKTRERSKAALLASQKPFKFIAREEQKQAIREKKLRELCRAKKKPKQFKARPVPRFIYRPPANVKPKREELYGDSRTQPKARDVLQSSPWPSHSTYRAFRDPRSPAMPRGKHRHRRLSPSDQGLEKWKEPFSEQSFRNCPVLCDQCCLYESLCDSNKRQKILADIRMGEEILKETRRPNPSPRHKSPRRSAHASARPCEYSPPMPTASSRGREQAIRRSEKARMKELARIGGAR",
    "output": "Involved in ciliogenesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MITIKCKDTNLDPLPVKIGIIGGSGLDDPDILEQRQERVVETPYGEPSDALIEGEINGVQCVLLARHGRKHDIMPSNVNYRANIWALRDVGCTHLIVSTACGSLREEIKPGNLVVPHDFIDRTTKRLQTFYDGKAQSPRGVCHLPMFPAFSERTRNILLQAAKELEIPAHDKATIVTIEGPRFSSRSESHMFRQWGGDLINMTTCPEVVLAKEAGLLYGSVAIATDYDCWRMGCEGVNVQDVLRTFAENVIKVKKILVNAVGRIAKEDWSEDILNAKQCVCNNTMSGAM",
    "output": "Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTARIIDGAALSQRIREEVAQRVQALTAKGVRPGLAVVLVGDDPASQVYVRNKVAACEKAGLHSVKEQYPADLTEAQLLERIDALNRDPSIHGILVQLPLPRHMDAHKVIEAIAAEKDVDGFHISNAGLLMTGQPLFRPCTPYGVMKMLESEGVALRGAEAVIVGASNIVGKPMAMLLLQAGATITICNSKTRDLGAQTRRADVLVVATGKPGMIDGSMIKPGAVVIDVGINRGADGKLCGDVDMASAREVAGAISPVPGGVGPMTIAMLLVNTVEAAERAAA",
    "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY",
    "output": "This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKYKSIMLLGTASSVGKSTVAAAFCRYFKKKGYRVAPYKALNISLNSFVTKDGDEIGRAQVVQAEACEIDPKEYMNPILMKPSAGFKTQVIVRGKVHCTMDAYKYKELNKYLKEKAKEAYDDISNDYDLIVLEGSGSCAEINLRETDIANMHTAKMADADVILVSDINRGGVFASIVGTIMLLTEEERKRVKGVIINKFRGKREFFEPAMRQIEEIIKIPVLGVMPYFDLDIEEEDSASIKLRKGNGKGIDIAIVRLPHMSNFTDFNSLGRIKDVCIRYAENPKDLENANMIIIPGSKNTIDDLIYLKESGFKEALINESSKGKLIFGICGGYQILGEKIIDSLGVEGDIREEEGLGLLNIVTSFNKEKTTKQVVAFDLEGNEVSGYEIHNGESVPTAKENIWIKEQNGNVLGMKNKEQNVFGTYIHGIFDEGDFGEKLINKLKKELNIEESNDVNYKDYKMSQYDKLCELLEENIDMAYVENLIRY",
    "output": "Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSFITLNNFFNTNTFFGLLPEQYAPFDPLIDVLPIIPVLFFLLAFVWQASVKFR",
    "output": "One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDPSLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL",
    "output": "Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKLNELYNNIGAKKNKKRIARGVGSGKGKTGGRGIKGQKSRSGVAIKGFEGGQTPMIKRLPKRGFNCISTKEYNIINIYNIEKALIDGRLSAADTITKEKLVEVGLINNKNNKNLVKLLSICSDDFSSPLSLKLDAYSSKAKDLIKKAGGKLL",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLVGAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWLSLMVIFLKDKQMGNSHEG",
    "output": "Efflux pump driven by the proton motive force. Confers resistance to a broad spectrum of chemically unrelated drugs (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV",
    "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. RNase H participates in DNA replication; it helps to specify the origin of genomic replication by suppressing initiation at origins other than the oriC locus; along with the 5'-3' exonuclease of pol1, it removes RNA primers from the Okazaki fragments of lagging strand synthesis; and it defines the origin of replication for ColE1-type plasmids by specific cleavage of an RNA preprimer. Involved in production of retron derived msDNA (a branched RNA linked by a 2',5'-phosphodiester bond to a single-stranded DNA). Strain K12 / MG1655 does not have retrons, however they can be expressed in this strain which requires this enzyme (tested with retron Ec86) ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSFLPLRSRSRSGAPHWVYIILYHIFTIPKIYSLPLLSGSHVLNSRDVADSGHSVGDEASVTTYYIISIILVLLGGVFAGLTLGLMGQDEVYLKVISTSGSNSEKKLAKRVLDLISRGKHWVLVTLLLSNVITNETLPIVLDRCLGGGWQAVVSSTILIVIFGEIIPQSVCVKYGLQVGAFFCPFVLVLMYLMYPVAYPIATLLDYMLGEDHGTMYKKSGLKTLVTLHRTMGVERLTKDEVTIISAVLDLKAKRVEEIMTPIENVFTMSADTILDDKTVEKIFNSGFSRIPIFLPNEPNNFIGMLLVRVLISYDPDDCLPISHFPLATLPETSPNTSCLNILNYFQEGKAHMCVVSKEPGSSHGAIGVLTLEDVIEELIGEEIVDESDVFVDMHQHIMRQQPGPLSKRHITSYLHHLYTSSHKEHKAADQADESSPLLSPSNSNHPSEHPQQDLNNKSWKQKSNDGYDRSNAVLSPTPQVTEHGTIIPSNLASNPLNVNKSFVTIKKPANVPKIITTHTPHSSKEPSPAPHSNDKSLSAEEQQLLSDHAELSRQAVLHTQRSGQPTQVTTSTKTTRNSPDSISIPNSGANHGNENQNVTISTSYQNTKNGIVESVITVKGVPKTIIGPAKDWDESKSEYGNENINQENSNRSDDRESSSSNASLFSSIKNKFKNENANNNDRSNFTDSLSRTSNYDANGSSSTIKR",
    "output": "Involved in metal homeostasis and more specially in manganese sensitivity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKALFSVLCLVLLVSILRAAVTKPDSGIFTGCLRNRTSLENPITDAIFTSRNTTTFLSSYVSYTKNKRYSSLNYQKLVAIVAAKHVSHVQATVVCAKANGIQLRIRSGGHDYEGLSYTSSVPFVILDMYNLRSITVDVSSKKAWVQAGATLGELYTKINEASQTLAFPAGVCPTVGVGGHITGGGFGNLMRKFGITVDHVIDAQLIGVNGKLLDRATMGEDLFWAIRGGGGASFGVILSWKINLVEVPKILTVFKVSKTLEQGGTDVLYKWQLVATKVPEDLFIRAWPQIVKGTKLGERTIGVVFFAQFLGPTDKLMEIMSQSLPELGLRREDCHEMSWFNTTLFWANYPVGTPTRVLLDRPSTPGEFFKSKSDNIKKPIPKEGLEKIWKTMLKFNFVWIEFNPYGGVMDRIPATATAFPHRKGNLFNLQYSTIWLDAKETENKLTMMKELYEVAGPYVSSNPREALFNFRDFDIGINPSGLNVDEAKIYGYKYFLGNLKRLMDVKAKCDPDNFFKNEQSILPARVM",
    "output": "Probable flavin-dependent oxidoreductase."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAAPQPQAAAVSSASGVSGPGSAGGPGPQQQPQPTQLVGSAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDNGQKSSDAPLQRFDKCLEEFYALCDQLELCLRLAHECLSQSCDSAKHSPTLVPTATKPDAVQPDSLPYPQYLAVIKAQITCAKDIHTALLDCANKVTGKTTAPSTGPGGSL",
    "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARYLGPKLKLSRREGTDLFLKSGVRAIESKCKIDNAPGVHGARKPRLSDYGLQLREKQKVRRMYGVLEKQFRNYYKESARLQGNTGENLLQLLEGRLDNVVYRMGFGATRAESRQLVSHKAVLVNGKVVNIPSFNVKASDVIAIREKAKKQSRIGAALEIAGQREVPTWVSVDATKMEGVFTRQPERSDLSAEINEQLIIELYSK",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNALAWSSAGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTSIRDVTPVPHNGARPPKRRRV",
    "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "NLYQFKNMIHCTVPNRSWWHFANYGCYCGRGGSGTPVDDLDRCCQIHDNCYGEAEKISGCWPYIKTYTYDSCQGTLTSCGAANNCAASVCDCDRVAANCFARAPYIDKNYNIDFNARCQ",
    "output": "PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGTVNEIHTSPYSKDAPLAASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPTNPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY",
    "output": "Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEPHLLMLGFLSFTIVPGCWAELCLYDPPEVPNATFKALSYKNGTILNCECKRGFRRLNELVYMACLGNSWSNNCQCTSNSHDNSREQVTPQPEGQKEQQTTDTQKSTQSVYQENLAGHCREPPPWRHEDTKRIYHFVEGQIVLYTCIQGYKALQRGPAISICKTVCGEIRWTHPQLTCVDEKEHHQFLASEESQGSRNSFPESEASCPTPNTDFSQLTEATTTMETFVFTKEYQVAVASCIFLLLSILLLSGFTWQHRWRKSRRTI",
    "output": "Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLREYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGSIQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEGNEETTEVVVDTAVETVEETVE",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPLMKFKPTSPGRRSAVRVVTPDLHKGAPHAALLDSQSKSGGRNHHGRITVRHVGGGHKQHYRIIDFKRNKEGIPARVERIEYDPNRTAHIALLCYVDGERCYIIAPKGLKAGDQVIAGANAPIKTGNTLPLRNIPVGTTVHGIELKPGKGAQIARAAGAAVQLVAREGIYATLRLRSGEMRKVPVECRATIGEVGNDEHNLEKLGKAGAKRWRGVRPTVRGAAMNPVDHPHGGGEAKAGQGNPHPVTPWGVPTKGYKTRKNKRTQQFIVRDRRG",
    "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTSVTDHSAHSMERAAEHTINIHTTAGKLAELHKRTEEALHPVGAAAFEKVHAKGKFTARERIYALLDDDSFVELDALARHRSTNFGLGENRPVGDGVVTGYGTIDGRDVCIFSQDVTVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHYVASGEQDAFDWVRDVLSYLPSNNFTDAPRYSKPVPHGSIEDNLTAKDLELDTLIPDSPNQPYDMHEVVTRLLDEEEFLEVQAGYATNIVVGLGRIDDRPVGIVANQPIQFAGCLDINASEKAARFVRVCDCFNIPIVMLVDVPGFLPGTEQEYDGIIRRGAKLLFAYGEATVPKITVITRKAYGGAYCVMGSKNMGCDVNLAWPTAQIAVMGASGAVGFVYRKELAQAAKNGANVDELRLQLQQEYEDTLVNPYIAAERGYVDAVIPPSHTRGYIATALHLLERKIAHLPPKKHGNIPL",
    "output": "Component of a biotin-dependent acyl-CoA carboxylase complex. This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate. When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKEKFERTKPHVNVGTIGHIDHGKTTLTAAITRVLSTKGQASFTDFSDIDKAPEEKERGITIATAHVEYETVNRHYAHVDCPGHADYIKNMITGAAQMDGAILVVAATDGAMPQTREHILLARQVGVPAMVVFLNKCDMVDDDELIELVEMELRELLDDYEFPGDDVPFIHGSALLALENPEDEDKAACIWELMDQIDSYIPEPERDVDQPFLMPVEDVFSISGRGTVATGRVERGIIKVGEEVAIVGVRDTVKTTCTGVEMFRKLLDEGRAGDNIGALLRGVKREDIERGQVLAKPGTITPHTKFKAECYILGKDEGGRHTPFFNGYRPQFYFRTTDVTGIVTLPEGIEMVMPGDNVAVEAELITPIAMDAGLRFAIREGGRTVGAGVISEIIA",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLNLVLMMIERVGLIVILGFLLSHIKTFRRLLHKQDGYVDKLKLICIFSVFTIVSNYTGIEIAGNTIMNENWLQGVSSSSTIANTRIMGVGISGLLGGPIVGIGVGSIAGIHRYMLGGTTALSCAISSILAGVITGYIGYIFKKYNRTITPKFSAVLSVFIVSLEMIMILLIVEDGISIVKTIAIPMILVNSFGSFILLSMIQAILRQEENAKALQTHKVLRIADKTLPYFRQGLTEESCKHVAQIIHRFTGTDAVSLTDTEKILAHVGLASDHHIPSHSLITGLSKEVLHTGKIMKAKSREVINCQHEGCPLQAAIVIPLTSHGNTIGTLKLYFKNPNQLSRVEEELAEGLAKIFSTQLELGEAELQSKLLQDAEIKALQAQINPHFLFNAINTVSALCRTDVEKARKLLLQLSVYFRCNLQGARQLLIPLEQELNHVQAYLSLEQARFPNKYEVKMYIEDELKTTLVPPFVLQLLVENALRHAFPKKQPVCEVEVHVFEKEGMVHFEVKDNGQGIEEERLEQLGKMVVSSKKGTGTALYNINERLIGLFGKETMLHIESEVNEGTEITFVIPKKVGEEEQIVKSISS",
    "output": "Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRSGVIAQKVGMTRVFTEAGEHIPVTVLKLGNCQVVAHRTTEKNGYVALQLGSGARKTVYMPKAERGQFAVAKVEPKRKVAEFRVSEDALIPVGAEIQADHFVVGQFVDVTGTSTGKGFAGGMKRWNFGGLRATHGVSVSHRSIGSTGGRQDPGKTFKNKKMPGHMGVDRITTLNLRVVQTDVERGLILVEGAVPGSKGGWISVRDAVKKALPADAPKPGKFRLANGGDEVAAPAAEQEGA",
    "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEILKNDVDPIETQDWLQSLDSLIREEGVERAQYIVEQVIGQARTSGVSLPTGVTTDYVNTIPVAEQPAYPGDHAIERRIRSAVRWNAIAMVLRSQKKDLDLGGHISTFQSAATMYEVCYNHFFKAATEKNGGDLIFFQGHAAPGMYARAFLEGRLTEEQMDNFRQEAFTDGLSSYPHPKLMPEFWQFSTVSMGLGPVNAIYQARFLKYLDNRGLKDTKDQKVYAFLGDGEMDEIESKGALTFAAREHLDNLIFTISCNLQRLDGPVNGNGKIVQELEGLFTGAGWEVIKVLWGSDWDKLFAKDTSGKLTQLMMEVVDGDYLTFKSKDGAYIREHFFGRYPETAALVADMTDDEIWALRRGAHDSEKLYAAYAKAQNATKPVVILAHQVKGYKIPEAESKNTAHQSKKMSYESLKGFRDFFELPLTDEQVEKLEYIKFAEGTPEYEYLHGHRKALNGYVPARRTKFDVEYKVPALEEFKALLEEQPRGISTTMAFTRALNILLKDKNIGKTIVPMIADEARTFGMEGLFRQVGIYNPHGQNYIPSDRDLVAYYREAKDGQVLQEGINELGATASWLAAANSYSVNNQPMIPFFIYYSMFGFQRVGDMMWAAGDQLARGFMVGGTSGRTTLNGEGLQHEDGHSHIQAGIIPNCITYDPSFAFEVAVIMQDGINRMYGEKQEDVFYYMTTLNEVMDQPAMPAGAEEGIRKGLYKFETVEGKKGKGHVQLLGSGAIMRHVREAAQILANDYGVTSDVFSAPSFNELAREGHDAARWNLLHPTETQRVPYVAQVLADLPTVASTDYVKGYADQIRAFVPSKHYHVLGTDGFGRSDSRANLREHFEVDARYVVVAALSQLAKEGTVSNQVVADAIAKFGLNVDRINPLYA",
    "output": "Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDPVVRKPDPGGVQHRVTKALRAIVGHACRHPIHTLLVTALTAATTHLHVLEGTYQATHRGLAPWAKETPLNVQSFLWGSRTVSLGEASAWKWQIDDRPKVPEDGQSDFHWALVTLDLPGASVDASIPFLSNTLSGFLGAEQTTPTPDSSPSPDHSALTFRVPYSQLDGFLQAVEIIPSEKEDDSWRLRSPREEGSPRSLGHWLGSSWLSFLHRVHHAETVDLVIIGLSYLAMNMTVVSLFRVMRHLGSRFWLAASVLLSGAFAFVLGLGITTTCDVPVDMLLLFEGIPYLVLTVGFEKPIQLTRAVLCVSEELWGGGQRQVPNGASSDDSRQNQLIPNIIQLAVDREGWYIVRSYLLEIGALALGAVLRPKDSLGHFCFLAAWTLLIDAVLLFTFYATILCVKLEITRIRSPGGLGQVNAKHPSGIFGHKVKSTNITWWKLLTVGGFVLCHFLQLSPFFYRVMGEYMANGTLPPTAVSPFKEAANGLNEIYLTARVEGFETRVTVLPPLQYVLESAGFNISATKRSTFDGVLDGLESPLGRLCLMGALVVSLVLNNHLIHAARWHAWPQARESAVPDGSYLSVPCSATAPEVCTRPPEETEALLKSNQAESLTDDELVELCLRGKIAGYSLEKTLERIAAGSSRSVTRLEAFTRAVRIRRAAVSKTPSTQNLCSGLAESLLPYRDYNYELVHGACCENVVGYLPLPLGVAGPMVIDGQALFIPMATTEGVLVASASRGCKAINAGGGATTMLKGDGMTRGPCLRFPSAQRAAEAQRWVESPLGHEVLAAAFNATSRFARLQTLTVAQAGIYLYIRFRTTTGDAMGMNMISKGVEKALEAMAAEGGFPDMHTVTLSGNFCSDKKSAAINWIGGRGKSVIAEATIPAETVRQVLKTDVDALVELNTAKNLVGSAMAGSLGGFNAHASNLVQAVFLATGQDPAQNVESSSCITTMKNIDGNLHIAVSMPSMEVGTIGGGTILEAQGAMLDLLGVRGAHSTEPGANARRLARIVAAAVLAGELSTCAALAAGHLVNAHMQHNRSAGATVKK",
    "output": "HMG-CoA reductase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) (By similarity). In this module, the cytosolic acetyl-CoA acetyltransferase catalyzes the formation of acetoacetyl-CoA (By similarity). The hydroxymethylglutaryl-CoA synthase then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA (By similarity). The rate-limiting step of the early module is the reduction to mevalonate by the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIKSLNERDNFLNRLREMEHKREKDEKQEKAARKVQKFWRGHRVQHNQRLLFRAEFDAVSDRQRGLEETIKMAQLLVNFYETNKDEERLVMTLSELVKLKTSDKEFEKRIRETQRLLLARCCIKFLKNATENTIFFHIFRYLEDYVTCHSKLFEASSKLGLFNAEFHLLEALIGKPTGKTVERASLNPRILQLLTRIFETFVNPSRSTSVSVNVANRLLKTICVNITDLNFSNYILYYIKDHIKPTSPNFTNLFEAMKSVDILNNWKVRPEIAETASLRLQSIFVSQIVHVSNTQSEDVKQYFNSLAVFLEHHSKIMRSLNVKEDLSEFGRLRTSVNNHLKQYCEEMLISNEFRRAACIYANLPGVQVETIISLRKYFSQFLDLLAASNTFVEALYAFIARLCPNGEFDPIDAKSPKVNALELFCNCLNKRVSSVADSDFVPTDIFVDFDHTVEFLRDVSIKLIHLMFPTMARGDLYSGNLKEKMYKAETDWKDVTESVFSILGAIYQKDIRLKYFPEEFWTNHGREVLSGIGEHRRMPRRRMPNGRLQIERTMDTEFVERLAAIYEMDSDSENDDEDEDNNLPAVLRRAICVMKHIPFIVPFMDRVKLFTRLLNQDKEKHYTSTFGMGFNGPSVTVRRDQVYMDAFETFAPKMQGDKVNDLKSMVRVKMVNWAGMNESGIDGGGIFREFLSELLKTAFNVERGFFTFTESKLLYPNPTAPFLLGVDCLAHFQFIGRMIGKLIYERQLQEVRFAEFFIAQIFETDKNKDVDLQHMKSFDPIIFKHLKALQKMNNRELDELQLDFSVVTSDMGLVRNVNLKPNGSKFRVTVENVHEYVRLYVNYHLKQRIASMVDAVRKGISEIISIEWMRMFAPHELQIMIAGYEEVFTAKELRKFCELRFAAGTQDINYEEMFWDVIDKLSNDDKKALLKFVTGCSRAPVDGFKSIQPRMGVLVIPSSDDELPTSATCMNMLRIPKYSNRTKLEEKLRYAINSGAGFELA",
    "output": "E3 ubiquitin-protein ligase that accepts ubiquitin from E2 ubiquitin-conjugating enzymes, such as ubc-18, in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ify-1 and cyb-1 targeting them for degradation in post-meiotic embryos."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPRKGHIAKRDVLPDPVYNSKVVTKFINSIMEDGKKGVAQKICYEAFGLIAKRSGKEALEVFEEAMNNVMPLLEVKARRIGGATYQVPIEVRPERRQTLGIRWMLIAARKRGEKLMSERVAGELLDASNNTGAAVKKREDTHKMAEANKAFAHYRY",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTNRWSFDVKKNLVTLILTWLCLSISTAQAARIKDVSEVAGVRSNQLIGYGLVSGLPGTGESTPFTDQSFNAMLQNFGIQLPPGTKPKTKNVAAVMVTTTLPAFAKQGQVVDITVSSVGSAKSLRGGTLLQTFLKGLDGKTYAIAQGNLIVSGFSATGADGSKIVGNNPTVGRISGGAMVEREVPSPFGRGDFITFNLLDSDFTTAQRMADAVNNFLGPNMASAVDATSVRVRAPRDISQRVAFLSAVENVNFDPADGSAKIIVNSRTGTIVVGKHVRLRAAAVTHGGMTVAIKENQQVSQPGPFGNGKTVVTQDSDIEVTEKQGKMFKFEPGLTLDDLVRAVNEVGAAPSDLMAILQALKQAGAIEGQLIII",
    "output": "Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDVTRLLLATLLVFLCFFTAYSHPPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKNSKQISRKEAEKKRSSKKEASMKKVARPRTPLSAPCVATRDSCKSPAPACCDPCASCQCRFFRSACSCRVLSLNC",
    "output": "Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALVDSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGIQHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMMNGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFPGSDVIIHQDPCSVVPREGKRSMLS",
    "output": "Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAFLLHQARFFTTVNHLRDLPPTVQPEVAFAGRSNAGKSTAINVLCNQKRLAFASKTPGRTQHINYFSVGPAAEPVAHLVDLPGYGYAEVPGAAKAHWEQLLSSYLQTRPQLCGMILMMDARRPLTELDRRMIEWFAPTGKPIHSLLTKCDKLTRQESINALRATQKSLDAYRDAGYAGKLTVQLFSALKRTGLDDAHALIESWVRPAAADEDRAAVAE",
    "output": "Necessary for normal cell division and for the maintenance of normal septation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQINDGDMTIEKQGVSLVVDPMSLQYLVGGAVDYTEGLEGSRFVVNNPNATSTCGCGSSFSI",
    "output": "Required for insertion of 4Fe-4S clusters for at least IspG."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKKVLALVVAAAMGLSSAAFAAETATPAKTAAPAKTTQTTQHHKKQHKKTVEQKAQAAKKHQKKDGKKAPAKSTSKTTSQPAA",
    "output": "Required for growth and/or survival at acidic conditions."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDSASLAVVVWAILLVLWLRRIFGQRSSLPLPPAPPGYPVIGNLLDLANNDVHIRARHWSRNFDDDVISLKVLGKTMIILNSPTAVSDLFDKRASNYSDRPDMPMIVDFIGWDWTFALMRYGPRWKEHRRVFNNHFNIGTSGASEDRHIQLRICRELLSLMFQSPSKYLENLRHYTGHIILKRTYGHTVVDEEDPYIRLVEAASQSTSEAAVPGAFLVDLFPSMKYIPEWFPGAQFKRKAREWRKLSEAMINAPYDMAKGKFDEGNAEACFVSACLEQNKTASGQGLSEELIKDTAAVAYAAGADTSVSTLTTFILAMTLYPDVQKAAQAELDALLGGERLPDFGDKTRLPYVTAILKEVLRWIPVLPMAVPHRAVNADTYKGYYIPAGAFVYGNAWAILHNPDIFADPETFRPDRFIENPTLLNPIDNGVFGFGRRACAGRVMALDTMWIAMASILAVFDISKAVDERGNEITPPVKLSPGTISHPAPFPCIIKPRSKAALELITQDD",
    "output": "Cytochrome P450 monooxygenase, part of the gene cluster that mediates the biosynthesis of melleolides, a range of antifungal and phytotoxic polyketide derivatives composed of an orsellinic acid (OA) moiety esterified to various sesquiterpene alcohols (Probable). The first step in melleolides biosynthesis is performed by the delta(6)-protoilludene synthase PRO1 which catalyzes the cyclization of farnesyl diphosphate to protoilludene . The orsellinic acid synthase armB produces OA by condensing acetyl-CoA with 3 malonyl-CoA units in a three-round chain elongation reaction folowed by a C2-C7 ring closure (By similarity). ArmB further catalyzes the trans-esterification of OA to the various sesquiterpene alcohols resulting from the hydroxylation of protoilludene (By similarity). The melleolides cluster also includes 5 cytochrome P450 monooxygenases, 4 NAD(+)-dependent oxidoreductases, one flavin-dependent oxidoreductase, and one O-methyltransferase (By similarity). The cytochrome P450 monooxygenases may be involved in protoilludene hydroxylation to elaborate melleolides with multiple alcohol groups, such as melleolide D, which carries alcohol functionalities at C-4, C-5, C-10, and C-13 (By similarity). The role of the NAD(+)-dependent enzymes remains unknown (By similarity). Numerous melleolides, including arnamial, show 5'-O-methylation of the aromatic moiety which may be catalyzed by the methyltransferase encoded in the cluster (By similarity). The flavin-dependent oxidoreductase might represent the dehydrogenase yielding the aldehyde in position 1 of arnamial and other melleolides (By similarity). Finally, several halogenase localized outside of the cluster, are able to catalyze the transfer of a single chlorine atom to the melleolide backbone, resulting in a 6'-chloromelleolide product (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNTNKIGVLLANLGTPDEPTTPAVKRYLKQFLSDPRVIDLPKFKWQFILNYMILPKRSPKVAKLYREIWTEQGSPLLAISRQQQQALQDYFNRQNQNVLVELGMSYGNPSIESATDRLIKAGVSKIIVLPLYPQYSSTTTASVLDAFARGLTQQRNIVPFEFIHSYHNDPLYIQALANTIRLADDEKLLFSFHGIPKRYQTEGDFYPEHCQKTAQLVADKLSLSNEQWLVTYQSRFGDEEWLQPYTDETLEKLPSQGVKKIAVICAGFSADCLETLEEIAEENKENFLNAGGQSYRYIPALNANTDHINALAKLIEAKI",
    "output": "Catalyzes the ferrous insertion into protoporphyrin IX."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRRTVKDFRNAKGQRLVYLTAYDYPTARLAEAAGVDAILVGDSLGMVVLGYPSTVPVTLEEMLHHTKAARRGAPETFLVADLPYLAYATLDRALLAAERLLKEGGADAVKLEGGEEVAEIVRGLVRAGVPVLGHVGLTPQTASQLGGYKLQGRRPEEAERILKGALALEEAGAYGVVLEMVPARLAKEVTERLSVHTVGIGAGPHTDAQVLVFHDVVGLYGDFKPRFVKRYLEAGRLIQEALSRYAQEVREGVFPGEEHSF",
    "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGATNFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRTGKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFMVVLPWAIAIARREADFWHYFFWVEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFAPIAILMARFVLHNVKEGVAALRVNGGINLVFGLVGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLCHSQKYLLPAFCPLGLALLFGFSIPDRVMESKQPQFFVEMTQAPLASSRYILADNVGVAAGLAWSLKRDDIMLYGHAGELRYGLSYPDVQDKFVKADDFNAWLNQHRQEGIITLVLSIAKDEDISALSLPPADNIDYQGRLVLIQYRPK",
    "output": "Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSLQNLTRFPRLELIGAPTPLEYLPRLSDHLGREIFIKRDDTTPLAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTGAENYLSNGNRLLLDLFNTQVEMCDALTNPAEQLDELATRIEAQGYRPYVIPVGGSNALGALGYVESALEIAQQCEGAVEISSVVVASGSAGTHAGLAVGLEQLMPQAELIGVTVSRSVADQLPKVVALQQAVANSLELQAKADITLWDDYFAPGYGTPNEEGMAAVKLLAQLEGILLDPVYTGKAMAGLIDGITQKRFKDEGPILFVHTGGAPALFAYHPHL",
    "output": "Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNSLVATPPVPPHFYEYSRLSSSRPMSTPTYTPNSRKRKADDDGNDHDGRMSASPTSSPAFTPRSLPSRNMKRARPNVSGRPLSLPRLLETLDTDALRGVLRSMCERHPGLVDEVVHTAPRPSVSSALQVLRNYQSTLQSSFPLGGNPASDYAYNRVRQPLSNLLDALSDFTPHFLPPNEIQPSLSLNYLDGATEIIHALPRWHTPQNNIERDSAYDEICKAWILVIREAAKRGGGIQLQYGGWDQKLAKHNQNSGGKLQAAVNELGASLGWMHGPETQSHASPGGNDFGSIREQLLSGTYGLGTPVKVGPW",
    "output": "Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSRFFIDRPIFAWVLAIIAMLAGALSLTKMPISQYPNIAAPAVSIQVVYPGASAKTVQDTVVQVIEQQLNGLDGFRYMAAESASDGSMNIIVTFEQGTNPDIAQVQVQNKLQLATPRLPEEVQRQGLRVVKYQMNFFMVVGLVDKTGKMTNFDLGNLIASQLQDPISRINGVGDFLLFGSPYAMRIWLDPGKLNSYQLTPGDVAQAIREQNVQVSSGQLGGLPTRSGVQLNATVVGKTRMTTPAEFEEILVKVKADGSQVRVKDLGRVVLASENFAISAKYRGQDSAGLGLRLASGGNLLETVKAVKAELEKQKAYLPEGVEVIYPYDTSPVVEASIDSVVHTILEAVVLVFLVMFLFLQSLRATIIPTLAVPVVLLAAFALLPYFGISINVLTMYAMVLAIGLLVDDAIVVVENVERLMHDEGLSPLEATRKSMGQISGALVGIGMVLSAVFVPMAFFGGSAGIIYKQFAVTIVICMSLSVLVALIFTPALCATILKAPENDAHHEKKGFFGWFNRSFDRNSARFERGVGGILKHRGRYLLIFALITAGTGYLFTQIPKAFLPSEDQGLMMTEVRMPLNASAERTEVVLQEVKDYLLKEEGQLVDHVMTVNGFNFAGRGQNSGLVLVVLKDWAARQAAGEDVLSVAERANARFARIKDATVMAFVPPAVLEMGNAMGFDLYLQDNLGLGHESLMAARNQFLELAAENPSLRAVRPNGKDDEPQFQVKIDDEKARALQVSIASINDTMSAAWGSMYVNDFIDLGRVKRVYIQGVDSSRIAPEDFDKWYVRNALGEMVPFSAFATGEWIHGSPKLERYGGISAVNILGEPAPGFSTGDAMIAIAQIMQQLPSGIGLSYNGLSYEEIRTGDQAPMLYALTVLIVFLCLAALYESWSVPMSVILVVPLGIFGAVLATLWRGLEADVYFQVGLMTTVGLSAKNAILIIEFAKELYEKEGVPLVKAAIEAARLRLRPIIMTSLAFTFGVLPMARATGAGAGSQHSIATGVVGGMITATVLAVFFVPLFYVVVVKVFERNKKPAALAEEELA",
    "output": "The inner membrane transporter component of an inducible organic solvent efflux pump. Involved in export of toluene and styrene but not of m-xylene, propylbenzene or ethylbenzene. Is not involved in antibiotic or AMP efflux."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPINVPDGLPAAEILTKEDVFIMEEKRAEHQDIRPLSIVILNLMPNKIITETQILRLLGNSPLQVDITLLYPETHRSKNTPEEYLIKYYQTFDSIKDQKFDGMIITGAPIEQMPFEEVDFWPELQKIMDWSKANVFSTLFICWGAQAGLYHFFGVPKYPLPAKMFGVFPHTLNRRDIRLLRGFDDIFYVPHSRHTEVRKEDIVKVPELEILSESEESGVYLVGTKGGRQIFVTGHSEYDPYTLKAEYDRDISYELPINVPQNYYPGDDPRQTPVVRWRGHSNLLFANWLNYYVYQETPYNLEELGNR",
    "output": "Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHHDFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH",
    "output": "Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTLKPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTIDGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEEFTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQAYVFTLLTSVYLGNKINIEEE",
    "output": "Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MYAVIVTGGKQYKVTEGEFLKIEKLELATGEAVTFDRVLLIGNGDDVKIGAPVVDGAKVVAEVVSQGRHDKVRIIKFRRRKHHMKRQGHRQWFTEIKITGIQA",
    "output": "This protein binds to 23S rRNA in the presence of protein L20."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPVNDNNLIWIDLEMTGLDPERDRIIEIATLVTDANLAILAEGPVLAIYQSDAQLALMNDWNVRTHTASGLVDRVRQSALDEEAAVAQTLAFLADWVPAGKSPICGNSIGQDRRFLFRYMPALEAYFHYRYLDVSTLKELARRWKPEILSGLKKNNTHQALDDIRESVAELAYYREHFIRL",
    "output": "3'-to-5' exoribonuclease specific for small oligoribonucleotides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSRVGKKIIDIPSDVTVTFDGSHVTVKGPKGELERTLNERMTFKQEENTVEVVRPSDSKEDRTDHGTTRALLNNMVLGVSQGYEKTLELVGVGYRAQMQGKDLVLNVGYSHPVEIKAEEGITFAVEKNTTVKVSGVSKEQVGAIASNIRSVRPPEPYKGKGIRYQGEYVRRKEGKTGK",
    "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDYNVKDFGALGDGVSDDTAAIQAAIDAAYAAGGGTVYLPAGEYRVSGGEEPSDGCLTIKSNVHIVGAGMGETVIKLVDGWDQDVTGIVRSAYGEETSNFGMSDLTLDGNRDNTSGKVDGWFNGYIPGEDGADRDVTLERVEIREMSGYGFDPHEQTINLTIRDSVAHDNGLDGFVADFQIGGVFENNVSYNNDRHGFNIVTSTNDFVLSNNVAYGNGGAGLVVQRGSSDVAHPYDILIDGGAYYDNGLEGVQIKMAHDVTLQNAEIYGNGLYGVRVYGAEDVQILDNYIHDNSQNGSYAEILLQSYDDTAGVSGNFYTTTGTWIEGNTIVGSANSTYGIQERDDGTDYSSLYANSVSNVQNGSVRLYGANSVVSDLPGTGQQATLEGTAGNDTLGGSDAHETLLGLDGNDRLNGGAGNDILDGGAGRDNLTGGAGADLFRVSARTDSYRTDSASFNDLITDFDASQDRIDLSALGFTGLGDGYNGTLLLQVSADGSRTYLKSLEADAEGRRFEIALDGNFAGLLGAGNLLFERTAIEGDAGDNALLGTSAAETLLGHAGNDTLDGGAGDDILVGGAGRDSLTGGAGADVFRFDALSDSQRNYDIGDNQGDRIADFAVGEDKLDVSALGFTGLGDGYNGTLALVLNSAGDRTYVKSYENGADGYRFEFSLDGNYLELLGNEDFIFATPSGQQLLEGSAGNDSLQGTAADEVIHGGGGRDTLAGGAGADVFRFSELTDSYRDSASYADLITDFDASEDRIDLSGLGFSGLGNGYGGTLALQVNSAGTRTYLKSFETNAAGERFEIALDGDLSALGGANLILDARTVLAGGDGNDTLSGSSAAEELLGGVGNDSLDGGAGNDILDGGAGRDTLSGGSGSDIFRFGGALDSFRNYASGTNGTDSITDFTPGEDLIDLSVLGYTGLGDGYNGTLAIVLNDAGTKTYLKNRESDAEGNQFEIALEGNHADQLDASDFIFATAAATTGIEVVGGSGTQTDQLA",
    "output": "Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G), producing a polymer with gel-forming capacity, required for the formation of the cyst coat."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSSNQNLAIAANAIDITAPESTIPNKSKVPNKSAESSQSTVPKAPSRREIRAQAQAFIDTLAPLQHTNSQKVYLEGSSADIRVGMRQILQTDTLVGGTDDAPIMEKNPPIRVYDCAGPYSDPEADINVRLGLVKLRQNWILARKDTEQLPCATSDFTQQRLADDGLDHLRFEAGSSAIVRPRRALQGKRVSQLHYARQGIITPEMEYVAIRENMALAEVQDEILNRKAKGEAFGALVGEPITAEFVRAEVARGRAIIPLNINHPEAEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWEVFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAKWCLSHHKENFLYSHFREICELCVAYDVSLSLGDGMRPGSIADANDAAQFAELETLGELVKIAWEYDVQTIIEGPGHIPMQLIKENMDKQLAHCGEAPFYTLGPQITDIAPGYDHFTSGIGAAMIAWYGCAMLCYVTPKEHLGLPNKQDVKQGLIAYKIAAHAADVAKGHPSAQIRDNALAKARFEFRWEDQYNLGLDPETARAYHDESLPQESAKVAHFCSMCGPKFCSMKITQDVRAYAAGLEAAQTKAEQVEAAAQAMQVTIKTPQELEAAMALKSAQFAASGAEIYQVIDKHVKDKLVAEAEEA",
    "output": "Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKLAQDMNVDEIFLKQAAEAIAVISSSPTHTDPIIRELLHRIRQSSPLSAVIPAPENVLKAGEPENMARGLIRIPETQTKRTGGNNHSKEGAQLYSCAKCQLKFSRSSDLRRHEKVHSLVLPHICSNCGKGFARKDALKRHSNTLTCQRNRKKLSEGSDVDVDELIKDAIKNGTGLL",
    "output": "Auxiliary transcriptional regulator of sulfur amino acid metabolism. Involved in the transcriptional activation of MET28."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARITILPDILCNQIAAGEVVERPAAVAKELLENSIDAGARRISLSIADGGRKEIRVVDNGSGMHPDDALLALERHATSKIRSIEDLQAIGSLGFRGEALPSIAAVSRFELVTREPDAVAGTFIRVEGGVVREVRETGSPAGTRITVRDLFYNVPARRKFLRAADTETAYICDQFQRLAMAHHAVHFQLINRERTQYDFPGAASPEERAGQVLGAETLKRAIPFCVENASARLRGMVGTPDLQRANSHSLFVFVNGRPVWDRAVNRAILAAFESLIPRGKFPVAVLFLELDPLHVDVNVHPTKREVRFKHPGGVIDTVRGAIRDALCHLRPLHGSAAAAPRPFSETADQRAFRDSLVREGQLSFDRGRPLSRPPGFPSERWRERHRPDAEPPYPLLREPAPTENPRREAGSPPAAPADSLFDEGAAPQPDNPDTDFFAEPKRAAGGPASTHAPVTVDTAAFADAFQAFEAATHLHAGDVPALAELPVIGQLANTYILLEAPDGLILIDQHAAHERIIFDALSFPAGGPARQRLIRPAVIDLPPRDAAMLRRWLPLLEEIGVEIESFGGDSFVVHAVPAPLGECPPEGLVRELLASAIEGDDAPRWNVLGRLAKTAACHRAVRAGQRLRPEEIRLLLEGLDRTRFASTCPHGRPVWYKMTLSDVARLFQRT",
    "output": "This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGSPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK",
    "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKKKTIFQCVILFFSILNIHVGMAGPEQVSMHIYGNVVDQGCDVATKSALQNIHIGDFNISDFQAANTVSTAADLNIDITGCAAGITGADVLFSGEADTLAPTLLKLTDTGGSGGMATGIAVQILDAQSQQEIPLNQVQPLTPLKAGDNTLKYQLRYKSTKAGATGGNATAVLYFDLVYQ",
    "output": "Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTTSTLQAPTRGWFDVLDDWLKRDRFVFVGWSGLLLFPTAYLAIGGWLTGTTFVTSWYTHGLASSYLEGANFLTAAVSTPADAMGHSLLLLWGPESQGDFIRWCQLGGLWAFVALHGAFALIGFMLRQFEISRLVGIRPYNAIAFSGPIAVFVSVFLIYPLGQSSWFFAPSFGVAAIFRFLLFLQGFHNWTLNPFHMMGVAGILGGALLSAIHGVTVENTLYEDGEQANTFKAFDTTQEEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVMGLWTSSIGIIGLALNLRAYDFVSQEVRAAEDPEFETFYTKNILLNEGLRAWMAPVDQPHENFVFPEEVLPRGNAL",
    "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MCNHHPKHSHGNDTIRIRGARTHNLKNVDLDIPRHKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQMMDKPDVDLIEGLSPAISIEQKSTSHNPRSTVGTVTEIHDYLRLLYARVGTPYCPEHKLPLSSQTVSQMVDAVLKLPEDTRVMILAPAVRERKGEFVDFFADLQAQGFARVRVDGEVYQLDEVPKLEKNIKHNIDVVIDRVKVKADIKQRLAESFETALRHGNERALAMEMDSGEEHWFSARFACPVCSYSLPELEPRLFSFNNPMGSCPTCDGLGNTNFFDPEKVVAHPELSLASGAIDGWDKRNQFYFQMIQSLARHYGFDVQAAWETLPAKIKKVVLHGSGKEVIDFTYLSERGTTFNRSHAFEGIIPNLERRYRETDSETVREKLREYQNHRACPSCGGARLRKEARYVYVSGEPLHEVSAWPLTKTHRFFETLDLDGNKKQIAEKILKEITERLGFLINVGLDYLNLSRSAETLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLLATLKRLRDLGNSVIVVEHDEDAIREADFVVDMGPGAGEHGGNVLIADTPENVAKCENSVTGQYLSGKKSIAVPSERTPVNPGRMLVLKGARGNNLKNVTLELPLGLITCITGVSGSGKSTLINDTLAKITARELNRAQEEPAPYDDIRGLEHLDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFASVPLSRERGYNVGRFSFNVKGGRCEACQGDGVIKVEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLDMTVEEACEFFDAVPTVSRKLQTLMDVGLGYIRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTGLHFADIALLLEVIGRLKGKGNSIVIIEHNLDVIKTADWIVDLGPEGGDGGGRIIASGSPEEVAKVKGSYTGKYLKNIL",
    "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNEVLAKGKKAKEIARELVLKSTEQKNEALSAIADQLILETAYILEENKKDIEEGKAKGFSDSLLDRLMLNEQRIVDMTEGIKQLIELRDPVGECVSAWERPNGLSIQEMRVPLGVVGMIYEARPNVTVDAATICLKTGNAVILRGSSSAIHSNKAIVAVIHRALKQTSLPQESVQLIEDTTRDSAKQLFTMNDYLDVLIPRGGKQLIDTVVREASVPVLETGAGNCHVFIDETADKQMAFDIINAKTQRPSVCNAIETIVLHEKWAEQYGSELFSSLKKRGVELRGDQKALAMDSTIVLASEEDWGTEFLSLTPAVKLVSSIEEAIHHINTYGSMHSEAIISENEEKVSKFFVSVDAAALYHNASTRFTDGSEFGSGAEIGISTQKLHVRGPMGLPALTSTKYVIRGNGQIRK",
    "output": "Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSNEPTSSFYELRLPPSDGISSVNFCPNSVNLLVTSWDSTVRCYDTQNNVQKWQYNHKGPVMDGCFPEKNKVFSGDVFGSVKHYDPVAGVEKEVGSHEDGVRSVVYNSDTQQLFTGGWDQQLKLWDIRSDKMEISNHDLQSKIFTMDVSPISNMLVIGTADKYVTIYDTRQMETHLQKRESSIKYQTRCIRTFTDGKGYALASVEGRIAMEYFDPSPAVQSKKYAFKCHRLTESGVDVVYPVNCIAFNPHYGTFATGGCDKNVFFWDGANRKRLHALKTYPTSISSMSFNTDGNILAVASSYTFEEGEKDHPPDQIFIHNILSEKIIKPIK",
    "output": "Involved in cell cycle checkpoint enforcement."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPVVKTKPTSPGRRHVVAVTNPSLHKGAPLASLTEKKRKNGGRNNAGRITVRHQGGGHKQLYRVIDFKRTKDGIPAVVERLEYDPNRTAHIALLKYADGERRYIIAPKGVSVGDAIASGQEAPIRVGSCLPLRNIPVGSVVHCIEMKPGKGAQIARSAGASAQVVAREGAYATIRLRSGEMRKVLVECRATLGEVSNSENNLRVYGKAGAKRWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVPTKGYKTRKNKRTDKMIVRRRKAK",
    "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRLFLLALLATLAVTQALVKEEIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWLDEYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSNKCVSS",
    "output": "May be involved in the specific maturation or degradation of a number of bioactive peptides. May play a role in the contractions of the heart, gut and testes, and in spermatid differentiation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKFSTAIIVSFLFIADFCAAQSGVLDISKFGGKPNSDIGQALTSAWNEACASTTAAKIVIPAGTYQLNGIELKGPCKAPIELQVDGTIQAPADPSVIKGTEQWFKFLYMDHLTLSGKGVFDGQGATVYKKAAPASAWSGKNSNSKVFMNFGFNFVNNSIVRGVTSKDSKNFHVMVFGCKNITFDGFTITAPGDSPNTDGIHMGKSTDVKILNTNIGTGDDCVSIGDGSKQITVQGVNCGPGHGLSVGSLGKFTTEENVEGITVKNCTLTATDNGVRIKTWPDAPGTITVSDIHFEDITMTNVKNPVIIDQEYYPWNQCSKKNPSKIKLSKISFKNVKGTSGTAEGVVLICSSAVPCDGVELNNVDLKFNGAPTTAKCTNVKPLVTGTAPVCQAPGAPAASTTATPAASKTATPAAGKSPAK",
    "output": "May function in the depolymerization of the pectin in its walls during pollen tube elongation, or in that of the pistil during pollination."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYCSICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVANKLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELASGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDILQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSLASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP",
    "output": "Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRIRVSYLLVLCFTLIWFRWTVVYSSFSDLDALLKLKESMKGAKAKHHALEDWKFSTSLSAHCSFSGVTCDQNLRVVALNVTLVPLFGHLPPEIGLLEKLENLTISMNNLTDQLPSDLASLTSLKVLNISHNLFSGQFPGNITVGMTELEALDAYDNSFSGPLPEEIVKLEKLKYLHLAGNYFSGTIPESYSEFQSLEFLGLNANSLTGRVPESLAKLKTLKELHLGYSNAYEGGIPPAFGSMENLRLLEMANCNLTGEIPPSLGNLTKLHSLFVQMNNLTGTIPPELSSMMSLMSLDLSINDLTGEIPESFSKLKNLTLMNFFQNKFRGSLPSFIGDLPNLETLQVWENNFSFVLPHNLGGNGRFLYFDVTKNHLTGLIPPDLCKSGRLKTFIITDNFFRGPIPKGIGECRSLTKIRVANNFLDGPVPPGVFQLPSVTITELSNNRLNGELPSVISGESLGTLTLSNNLFTGKIPAAMKNLRALQSLSLDANEFIGEIPGGVFEIPMLTKVNISGNNLTGPIPTTITHRASLTAVDLSRNNLAGEVPKGMKNLMDLSILNLSRNEISGPVPDEIRFMTSLTTLDLSSNNFTGTVPTGGQFLVFNYDKTFAGNPNLCFPHRASCPSVLYDSLRKTRAKTARVRAIVIGIALATAVLLVAVTVHVVRKRRLHRAQAWKLTAFQRLEIKAEDVVECLKEENIIGKGGAGIVYRGSMPNGTDVAIKRLVGQGSGRNDYGFRAEIETLGKIRHRNIMRLLGYVSNKDTNLLLYEYMPNGSLGEWLHGAKGGHLRWEMRYKIAVEAARGLCYMHHDCSPLIIHRDVKSNNILLDADFEAHVADFGLAKFLYDPGASQSMSSIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELIIGRKPVGEFGDGVDIVGWVNKTMSELSQPSDTALVLAVVDPRLSGYPLTSVIHMFNIAMMCVKEMGPARPTMREVVHMLTNPPQSNTSTQDLINL",
    "output": "LRR receptor kinase involved in the regulation of root and shoot growth, and root nodule organogenesis . Involved in long distance nodulation signaling events . Involved in the autoregulation of nodulation (AON), a long distance systemic signaling from root to shoot and back again, which allows legumes to limit the number of root nodules formed based on available nitrogen and previous rhizobial colonization . Acts from shoot to root to control AON . Involved in the regulation of root colonization by arbuscular mycorrhizal (AM) fungi ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAGVLGMILAGGEGSRLRPLTESRSKPSVPFGGSYRLIDFALNNFVNADLMRIYVLTQFKSQSLFHHLKKGWNINGITDRFIDPIPAQMRTGKRWYEGTADAIYQNLRFMELEEPDQVCIFGSDHIYKMDIKQMLNFHTEKKASLTVSALRMPLKEASQFGVIEVDAEGRMIGFEEKPANPKSIPGEPDFALVSMGNYVFEAQVLFSELVEDADNEASSHDFGKDIIPKMFPRGDVFVYDFSTNRISGEKEEVYWRDVGTIDAYWQAHMDLLEKDAPFSLYNRKWPLHTYYPPLPPATFTDSDNGRVQIIDSLVCNGSYVRGSRIEKSVLGFRSNIASACDISECILLGDVKIGEGCVLRRVIVDKDADIAPGTQIGVNLQEDKKHFHVSEEGIVVIPKGARVGY",
    "output": "Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MALTNEDIINAVSEMSVMQVVELIKAMEEKFGVTAAAATVAAAGPAAAAAEEQTEFTIVLAEAGDKKVNVIKVVRELTGLGLKEAKAVVDGAPGVVKEGASKEEAEAAKKALEEAGAKVELK",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLYFLLQPLARDVRLFNLLNYITFRAAAAFVTALLVSFILGPAIIRRLRAMAVHQVVREGTPDTHAGKGTTPTMGGLIILAATFAPVLLWSRLSNRYVLLAMAVTAWMGVIGFLDDYLKLKQKREGKKNEGLVERYKLAGQVLCGLGLGAYLLLSPISTLPGASTTLPFFKYVLVVPAVAWAAWLYIPWVTFILTGVSNAVNLTDGLDGLSSGLVAIAVLTLGLFAYVLGRVDTSAYLQVFYLRGAGELTVFCAAVVGACIGFLWYNAHPAQVFMGDTGSLALGGAVGAIAILLKSEFLLLFVGAVFFAETVSVILQRTVFKYRLRRYGREYAQKHRVFRRAPLHHHFEMMGWPETQVVVRFWIIGILCAILALSTLKLR",
    "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFFRNLTLFRFPTTLDFSQIDTLLPPVQLKPVGPLEMSSRGFISPFGRDEQGVLSHRLEDFLWLTVGGEDKILPGAVVNDLLERKVAEIEEKEGRRPGGKARKRLKDDLIHELLPRAFVKSSRTDAILDLQHGYIAVNSSSRKSGENVMSEIRGALGSFPALPLNAEVAPRAILTGWIAGEPLPEGLSLGEECEMKDPIEGGAVVKCQHQELRGDEIDKHLEAGKQVTKLALVLDDNLSFVLGDDLVIRKLKFLDGALDQLEHSEDDGARAELDARFTLMSAEIRRLFLLLETALKLSKAE",
    "output": "May be involved in recombination."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSDGGKSSSSYFHFFAGLNSGILSAVLLQPADLLKTRVQQSRSSTLFGTIQSIASGPNPVRQFWRGTLPSTLRTGFGSAIYFSSLNALRHRASLGAAGRADAAAKGAEHSSSLPKLSNTANLATGAFARTWAGFIMMPITVLKVRYESNLYAYNSLFTASRDIFRTEGLKGFFAGFGATAVRDAPYAGLYVLFYEQSKRKLSSLATKIEQTSGASTKLSTSTSAGINFVSGVAAAGLGTTITNPFDAIKTRIQLMPERYGNMVQATKKMYMEEGLRCFFDGLGIRIARKAVSSALAWTLYEELIRRAETLKEVVEDKI",
    "output": "Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMSVADIVEKEGWGGFRARETAALEAVSAPSTVVATGGGIILTEYNRRYMHRVGVVIYLCAPVSTLVNRLEAEPEADLRPTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKAPAQVVSEIIAALPPSTQRLQGDVYT",
    "output": "Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTRTGPPINPISWDTKTIVPDDGSRIDSVACQDARPKGRIRRSMTACHTCRKLKTRCDVDPRGHSCRRCLSLRLDCELPETTERFQDNASTWSDATAVPSIEERLVSLERGMGEMIHLMRQIVKSSPSMPCSPTFQTRNHSIDGTSSSDSMSSSFYPLKPAQLIRDLQAECFGERAHFSDADILGDIVTQGIVDSKLSVKLIELFVEHFGHWVSINHSSSLQRSNTLLFNTACLLASRYMPGLPQHTVRDISLYVQHAVAKVLWKPPPMTSDMLQALTLLCLYSTSIHKEGLMDDWLLSGISINHALISFNFLNTLPGDNLSPDELLAQLRLWNTLCATQLHSALANGRTVNIQQQYINQCPRILEHAGATPEDGRIVAEIQLYRIALRLQHSQSRLQFAESEYEELERWRMEWAHLLTTNGDSTLNLNLWFCQLLLHRTAARLQPDSERLLPEICGTARLIITQFLQTRFTSAPALIDHVYFIVGYAALTLCDYTLTDPLINQVRGFLLHLAPGGDNLSYRIACIVGEVQRRYSEATAVVAAGSHSSSPVAEVKGAQMFGSSHHHRTGMELSQLMSSPEGLDSLVEGYNCLEQMMPGYAASQPAFEAPDLFHHSPTTGVTGGAMPIGLVPRALHDW",
    "output": "Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRSKLGTHFKKASVISGSVTQSKVNQSTFSRSIIGTSSRKSLNLHAESKMGERNLSMVSKQSIKIFDDDGKDVSPQPLFQAEPGTVPQKQNKLFTPPDASGIGASDIFSSISLQHTAFNASFVGPFTRSTFGASTVSRSSKETESMTEDIEETGFKREIASLSEIQGKQHEMQPTEEDLDKIINIFLTDTETLWLLDMPPALTATDSENADLVRVRNQAYEDLCKDKVGNDKYIERMMQTFSGAPKNKEVQCDRIILEDTGVMASVWDLYDSYLSPESLPMKEAVDRAIETKNISSSRLSESRGTQSMNSLGRGDSFSSSIADIERLALTRIPDEVEPDSEEILKSEKFLQDLFFMERVVVENTFQSRLAAYRQLPVIADPDEDEDKISAMPSNIVSPSLNRLWSFACDVTKGHNVSSMSWNKKNSDLLAVGYGQFGFAEQKGGMACCWSLKNIMWPERIFHCECGVTAVDFSAVHPNLLAVGMYNGTVAIYNVQNNEDFPVLDSSDNPNKHTSPVWQLKWIEHDRGNLGDDKGEILVSVCADGRITRWHIRKGLDCNDLMKLKRTGSGKSKKSSNEKERKGEAFISRQAPGMCFDFLPKDSNIYLAGTEEGHIHKCSCSYNEQFLDTYRGHKGPVYKIVWSPFCPDVFLSCSADWCIHLWQQDVLLPILTFSNTTNAVYDIMWSPSSALMFGAVSENRVEIWDLGVSIIDPVIVNEANPGVKLTSILFAKNTDCVLIGDSD",
    "output": "Plays a critical role in the assembly of axonemal dynein complex, thereby playing a role in ciliary motility."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPPKTRSTARRSGRRVVKKNVAQGHAYIKSTFNNTIVSITDPSGAVIAWASSGHVGFKGSRKSTPFAAQLAAENAARKAMDHGMKKVDVFVKGPGSGRETAIRSLQAAGLEVTSISDVTPQPFNGCRPPKRRRV",
    "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFGDSDGSKDANPGAPPSTTDPPFPNRELTLSSYLCEKPTLASAAAGGGGGAGPSSPPNPAAAAAGDDGKHCVERDFLHLSAPKRGDPPGDDSSVVGGKKPRLDSLQLSLSLNSDGPAAPPSSQPPLASLLQPVPATDGDLRGAAAAAAVPAAPARRTYSATTARTRSINSDDMSYSYSIFSHNPSCSLTHNSTDIYAAGEGTNGSVHSRFNFRPMGDGSVAFATPPLKEGTSSFFPTELPARMAAAAAAAAASAGGSFDGGRGGLHASRPDKILRDIVSDSVTAMAQVLQDFPSERLELLREAVRGMIDSHEKRDELASLQRKLERRSDLTTETLGRANRTQLEILVAIKTGIATFVTGKGRVPSSELVEMFLMTRCRNLNCKSTLPVDDCDCKICSTKKGFCSACTCSVCHKFDCAANTCTWVGCDVCGHWCHVACALERNLIRPGPTLKGPIGTTEMQFQCLACNHSSEMFGFVKEVFNCCAENWNAETLMKELDFVRKIFAGCEDFEGKGLHAKAEEVLSLLGKKIISPLDATNSILQFFKYGVTDYSVTGSTSKGILAAQASQSTDMRSLQTPTITPPKSSFNFKTTTSILDTDALKPSPKPLSIEPHFSTASKEDDSSLETIVKCKEAEAKLFQKLADDARKEVDSYRQIVRSRTQKLEEEYAAKLAKVCFQETEEKRRKKLEELKMLENSHYDYLKMKMRMQTDIQGLLERMEATKKMWV",
    "output": "Probable transcription factor that functions as regulator of metal transporter genes responsible for essential metals delivery to shoots and normal plant growth . Required for the maintenance of metal transporter gene expression, such as IRT1, IRT2, ZIP1, ZIP9, NRAMP1 and NRAMP5 ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MELAKSFEPGNIENRWYDRWEAAGYFKPSMDTDRPSFCIQLPPPNVTGTLHMGHAFNQTIMDGLTRYYRMKGDNTLWVPGADHAGIATQIVVERQLAEQGVSRHDLGRDTFIGKVWEWKEKSGGTITSQMRRVGCSVDWDKEYFTMDDKMSTAVTEVFVRLYEQGLIYRGKRLVNWDPKLGTAVSDLEVISEEEDGKMWHIRYPVVGSDDVVVVATTRPETLLGDVAVAVNPDDERYRHLVGKQLELPLTGRTIPVIADDYVDAAFGTGFVKITPAHDFNDYQVGKRHNTALINVMSLDATMLAKAQVFGFDGSAQGSIDLPAAYAGLSTADARKAMLADLDAAGLLVDTKPHKLMVPRGDRTGSVIEPLLTDQWFVAMTKVGEGDATGKSITQKAIDAVESGEVRFVPENWVNTYNQWMNNIQDWCISRQLWWGHQIPAWYDEDGKAYVGRTLEEVQAKAPGKTLRRDEDVLDTWFSSALVPFSSLGWPNETPELKAFVPSQVLVTGYEIIFFWVARMIMMTTHFLGKVPFKDVYIHGIVRDHEGKKMSKSEGNVIDPVDLIDGIALPELITKRTTGLRRPEKAPQIVKATEKLFPEGIPAYGTDALRFTMASYASLGRSVNFDFKRAEGYRNFCNKLWNATRFVMMNVEGKDCGQDESLPLEYSFVDKWIISRLQELEAAVTEALDTYRFDMASQLIYEFVWNEYCDWYVELAKVQLANGNEAQQRATRRTLVRVLEVALRLTHPLMPFITEELWQTVAPLANAKKTDSIMVAAWPVADMSKVDAEACGRMTVFKELVNAIRNLRGEMNLGPSVKAPLFVEGPAAYADFLPYARLLGRLSDAAVVEKLPDADAPVAIAGEARLMLKVEIDKAAETARLTKEIGKAESDVEKLTAKLEKPGYVDKAPAQLVERDRAQLADLTDKLAKLKAQLLKLA",
    "output": "Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKKSLSLVLASGSPRRKELLAQLGYDFDIVLPDIEEAKQADEQAQDYVLRLSLEKAQAGLALAKPDSVVLGSDTVVVCDDRVLEKPKSFEDSKRMLTDLSGRRHQVMTAVSVVSSEQQHSVVVTTDVWFKPLTHEEIEQYWQSGEPCDKAGSYGIQGLGGRFVTRIEGSYHAVVGLPLFETDQLIQEFL",
    "output": "Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLAKGLPPRSVLVKGCQTFLSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVSVLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRGILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFNQEATQQ",
    "output": "A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones . Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal . Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin) ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSSAGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV",
    "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLNKLSRLLADAGISLTDHQKTLLVAYVDMLHKWNKAYNLTSVRDPNEMLVRHILDSIVVAPYLQGQRFIDVGTGPGLPGIPLAIVLPDAHFTLLDSLGKRVRFLRQVQHELKLENITPVQSRVEAYPSEPPFDGVISRAFASLNDMVSWCHQLPGEKGRFYALKGHLPGDEIASLPDDFSVESVEKLRVPQLEGERHLVIIKSNKV",
    "output": "Specifically methylates the N7 position of guanine in position 527 of 16S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLIFEGKEISTDSEGYLKETTQWSEALAVAIAANEGIELSAEHWEVVRFVREFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGLPKPVKCI",
    "output": "Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MWIESDAGVAIDRHARGACSLGEAGCATYCFYQGKHHGGCCGENYTKCLGTCYCNGSGYEYRCHSCDL",
    "output": "Shows antibacterial activity against numerous Gram-positive bacteria (Probable). It selectively inhibits peptidoglycan biosynthesis through complex formation with the cell wall precursor lipid II (1:1 molar ratio) thus inhibiting cell wall synthesis ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLSIILLLMQLVAADIAVVGPSLDQSFDASGGTAKIPIQWLFTPNTPSQDDFTSLTFSLCSGPNYKIEAFKVIGKLSDIGTTDFEAEVSQSVGANGYYYVQIYAATTDGYTIHYSPRFKLTGMTGSKLPDTLLITAPPTPETRVTTGDLGATIDSKSFDIPYGEQNGKAKFAPMQTQPGTKITATTWSRRYATSAVSFFTSLTATPVQHTTLTPGWSYYISSDYNYAPPAPFPSDNGGWYDPKKRQSFTTRKLNMDKLRKRRQTS",
    "output": "Involved in cell wall beta(1->6) glucan synthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAEEMRQELSALAAIFCGPHEWEMLSCSETDGAVFRIHTTAEGLAGEDVPLELAFHLPAGYPSCLPGISVNSERLTRAQCVTVKEKLLGEARRLLSEPMVHELVLWTQQNLRHILSQTETESSNGTCTLPESSTVDGGLWMTLLRLDHMRARTKYVKVVEKWASELRLTGRLMFMGKMILILLQGDRSNIKEYLILQKTSKVDVDSSGKKCKEKMISVLSETKVQTEHKRFLAFEVKEYSTLEELQKEFETAGLQELFSECVLGLVK",
    "output": "Enhancer of SUMO conjugation. Via its interaction with UBE2I/UBC9, increases SUMO conjugation to proteins by promoting the binding of E1 and E2 enzymes, thioester linkage between SUMO and UBE2I/UBC9 and transfer of SUMO to specific target proteins which include HIF1A, PIAS, NFKBIA, NR3C1 and TOP1. Positively regulates the NF-kappa-B signaling pathway by enhancing the sumoylation of NF-kappa-B inhibitor alpha (NFKBIA), promoting its stabilization which consequently leads to an increased inhibition of NF-kappa-B transcriptional activity. Negatively regulates the hypoxia-inducible factor-1 alpha (HIF1A) signaling pathway by increasing the sumoylation of HIF1A, promoting its stabilization, transcriptional activity and the expression of its target gene VEGFA during hypoxia. Has no effect on ubiquitination."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSPTPIKHYLQFSDLSADEYEYLLDRARILKAKFKNYETWHPLHDRTLAMIFEKNSTRTRLSFEAGIHQLGGHAVFLNTRDSQLGRGEPIEDAAQVISRMVDIIMIRTFGQEIIDRFAKHSRVPVINGLTNEYHPCQVLADVFTYIEQRGTIAGKTVAWIGDANNMAYTWIQAAERLDFTFHFSAPPGYQLDPAMVPDWAASRVKVFDNPLDACQGAHLVTTDVWTSMGFEAENDARKRAFKDWMVTTAMMDRAADDALFMHCLPAHRGEEVEAAVIDGPRSVVWEEAENRLHVQKALMEYLLCGRY",
    "output": "Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRTNPTTSRPGISTIEEKSVGRIDQIIGPVLDITFPPGKLPYIYNALIVKSRDTADKQINVTCEVQQLLGNNRVRAVAMSATEGLMRGMEVIDTGTPLSVPVGGATLGRIFNVLGEPIDNLGPVDTSATFPIHRSAPAFIELDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIEESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKKGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLASKGIYPAVDPLDSTSTMLQPRIVGNEHYETAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEASTKAINLEEESKLKK",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSNDIEFRKLEHLFVCNYCDVEYKKGTLLEDVELIHSGISNCDLEDIDTSINLFGKNLGAPIIVAAITGGHSKAKEINKNIAIAIDELNLGMGVGSQRAALINEELMETYSVVRDYTSSLVLGNLGAVNFIEDGWDEETIHKAVEMIDADGMAIHFNPLQEAIQPEGDYNFKGIEILKDIMENYNKTYNNKSNKKIPFIAKQVGEGFSKEDALLLNGLGFDSIDVGGSGGTSWAAVEYYRIKDEESKKFSKKYLEWGIPTAASILEVKQNFDKPIIATGGIRSGMDIAKSMAIGAQCCGVALPVLKAALRGSEDVIKLIENYIEELKTTMFLMGCDNVNELMNSRYIIKNELKEWI",
    "output": "Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSEVEKTYCGFIAIVGRPNVGKSTLLNELLGQKISITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMNRAASSSLGDVELVIFVVEGTHWTADDEMVVNKLRSLQCPVLLAINKVDNVTDKTKLLPHMQFLSQQMNFLDVVPISAEKGMNVDTIASIVRKHMPEAEHHFPEDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNIHGLILVEREGQKKMVIGNKGSKIKVIGTEARQDMERMFEAKVHLELWVKVKSGWADDERALRSLGYTDDLK",
    "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNISNIKIMLLGSGELGKEFIIAAQRLGIHTIAVDRYKNAPAMQVAHESYVIDMLNSDALEQLILAKNPTYIVPEIEAINTDSLVKLEAHNFNIIPCAKATKLTMDRQGIRALAVQQLNLQTSKFAFANSEQEYLDVIQSIGLPFVIKPVMSSSGKGQSIVKEHNEIKKAWDYAQNGSRGHAKGVIVEQFIDFDYEITLLTVRHKDGTSFCDPIGHIQKDGDYRFSWQPHTMPDTALAKSQEIAKEITDALGGYGVFGVELFIKGDEVFFNEVSPRPHDTGMVTLISQNINEFELHLRAIVGLPIPDIQTLQPSASAAILLEGDTANASICGIDKALADANVDIRIFSKKEIHGKRRMGVVLAKAQNTHIALETSKQALAHIHLTK",
    "output": "Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MADQAKLGGKPSDDSNFAMIRDGVASYLNDSDPEETNEWMDSLDGLLQESSPERARYLMLRLLERASAKRVSLPPMTSTDYVNTIPTSMEPEFPGDEEMEKRYRRWIRWNAAIMVHRAQRPGIGVGGHISTYAGAAPLYEVGFNHFFRGKDHPGGGDQIFFQGHASPGMYARAFMEGRLSEDDLDGFRQEVSREQGGIPSYPHPHGMKDFWEFPTVSMGLGPMDAIYQARFNRYLENRGIKDTSDQHVWAFLGDGEMDEPESRGLIQQAALNNLDNLTFVVNCNLQRLDGPVRGNTKIIQELESFFRGAGWSVIKVVWGREWDELLEKDQDGALVEIMNNTSDGDYQTFKANDGAYVREHFFGRDPRTAKLVENMTDEEIWKLPRGGHDYRKVYAAYKRALETKDRPTVILAHTIKGYGLGHNFEGRNATHQMKKLTLDDLKLFRDKQGIPITDEQLEKDPYLPPYYHPGEDAPEIKYMKERRAALGGYLPERRENYDPIQVPPLDKLRSVRKGSGKQQIATTMATVRTFKELMRDKGLADRLVPIIPDEARTFGLDSWFPTLKIYNPHGQNYVPVDHDLMLSYREAPEGQILHEGINEAGSVASFIAAGTSYATHGKAMIPLYIFYSMFGFQRTGDSIWAAADQMARGFLLGATAGRTTLTGEGLQHMDGHSPVLASTNEGVETYDPSFAYEIAHLVHRGIDRMYGPGKGEDVIYYITIYNEPTPQPAEPEGLDVEGLHKGIYLYSRGEGTGHEANILASGVGMQWALKAASILEADYGVRANIYSATSWVNLARDGAARNKAQLRNPGADAGEAFVTTQLKQTSGPYVAVSDFSTDLPNQIREWVPGDYTVLGADGFGFSDTRPAARRFFNIDAESIVVAVLNSLAREGKIDVSVAAQAAEKFKLDDPTSVSVDPNAPEE",
    "output": "Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGHSGHDVKYGRHRTRRSFARISEVLELPNLIEIQTASYQWFLDEGLREMFRDISPIEDFAGNLSLEFIDYDLGEPKYSVEESKNRDANYAAPLRVKLRLINKETGEVKDQEVFMGDFPLMTEMGTFIINGAERVIVSQLVRSPGVYFNGKLDKNGKKGFGSTVIPNRGAWLEYETDAKDVVHVRIDRTRKLPVTVLLRALGFGSDQEIIDLIGDNDYLRNTLEKDNTDNAEKALLEIYERLRPGEPPTVDNARSLLVSRFFDPKRYDLASVGRYKINKKLHLKNRLFNQTLAETLVDPETGEIIASKGDILDRRNLDQIIPNLENGVGFRTLRPTDGVMEDSVLVQSIKIYAPNDEEKEINIIGNAYIEENVKHITPSDIISSISYFFNLLHGVGDTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDMTTITPQQLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRERAGYEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSFAKVNKFGFIETPYRRVDPETNRVTDKIDYLTADEEDNYVVAQANSKLDEQGTFTEEEVMARFRSENLAVEKERIDYMDVSPKQVVSVATACIPFLENDDSNRALMGANMQRQAVPLMHPEAPFVGTGMEHVSAKDSGAAVTAKHDGIVEHVEAREIWVRRVSLVDGKEVTGGIDKYTLRKFVRSNQGTCYNQRPNVAEGDRVVKGEILGNGPSMDSGELALGRNVLVAFMTWDGYNYEDAIIMSERLVKDDVYTSIHIEEFESEARDTKLGPEEMTRDIPNVGEDALRDLDERGIIRVGAEVKDNDLLVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGGGGIVLDVKIFTREAGDELPPGVNQLVRVYIVQKRKIHEGDKMAGRHGNKGVISRILPEEDMPFMPDGTPVDIMLNPLGVPSRMNIGQVLELHLGMAARALGIHVATPVFDGANEEDVWSTVEEAGMARDAKTILYDGRSGEAFDNRISVGVMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTIKSDDVVGRVKTYEAIVKGESVPEPGVPESFKVLIKELQSLGMDVKMLSADEEEIEMRDMDDDDFTNQNDAFNIVQPENAAAEKTE",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLSDIPRDALLRPLTRNEVVGMLVRLTVFGAATYYSIKWVVDALDPTQKQKSQAKKRAEQLMKQIGVEGVSLTEYEMNIATLLVDPRSIKVTWRDVAGLDEIISEMQDTVILPFQKRHLFSGSKLLQPPKGVLLYGPPGCGKTLIAKATAKASGCRFINLQASTLTDKWYGESQKLTAAVFSLAVKIQPCIIFLDEIDSFLRNRSSMDHEATAMMKAQFMSLWDGLDTGENSQVMVMGATNRPQDVDAAILRRMPTAFHVGLPNAAQREEILRLILSGENLSNAINLKEIASQSEGYSGSDLKELCRDAAMYRVRDYVRKQQMKQIAQQFQLDEEEEHVDSRQLRPVTQLDLLFGLDKMRESKQATATTDPANLREVPLD",
    "output": "Outer mitochondrial translocase required to remove mislocalized tail-anchored transmembrane proteins on mitochondria (By similarity). Specifically recognizes and binds tail-anchored transmembrane proteins: acts as a dislocase that mediates the ATP-dependent extraction of mistargeted tail-anchored transmembrane proteins from the mitochondrion outer membrane (By similarity). Also plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNTKTVKSMAGIVLSQISLVALFPLCICYQTHQSTSSVASLSPQFYENSCPNAQAIVQSYVANAYFNDPRMAASILRLHFHDCFVNGCDASVLLDSSGTMESEKRSNANRDSARGFEVIDEIKSALENECPETVSCADLLALVARDSIVICGGPSWEVYLGRRDAREASLIGSMENIPSPESTLQTILTMFNFQGLDLTDLVALLGSHTIGNSRCIGFRQRLYNHTGNNDPDQTLNQDYASMLQQGCPISGNDQNLFNLDYVTPTKFDNYYYKNLVNFRGLLSSDEILFTQSIETMEMVKYYAENEGAFFEQFAKSMVKMGNISPLTGTDGEIRRICRRVNHDV",
    "output": "Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAVWQAASGKVYLPPSTPVARVQSTDEYVQRTNIYYHAYSDRLLTVGHPYFNVYNVQGSKLQIPKVSGNQHRVFRLKLPDPNRFALADMSVYNPDKERLVWACRGIEIGRGQPLGVGSVGHPLFNKVGDTENPNSYKASSTDDRQNVSFDPKQLQMFIIGCAPCIGEHWDKALPCDDGNIQQGSCPPIELINSVIEDGDMADIGYGNLNFKALQQNRADVSLDIVNETCKYPDFLKMQNDVYGDSCFFYARREQCYARHFFVRGGKTGDDIPAGQIDEGSMKNAFYIPPNSSQAQYNNLGNSMYFPTVSGSLVSSDAQLFNRPFWLQRAQGHNNGICWFNQLFVTVVDNTRNTNFSISINSDGTDVSKITDYNSQKFTEYLRHVEEYELSLILQLCKVPLKAEILAQINAMNSNILEEWQLGFVPAPDNSIQDTYRYIDSLATRCPDKNPPKEKVDPYKNLHFWDVDLTERLSLDLDQYSLGRKFLFQAGLQQTTVNGTKTVSSRISTRGIKRKRKN",
    "output": "Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAITAQMVKELREKTGAGMMDCKKALTETNGDMEKAIDFLREKGIAKAAKKADRIAAEGLTFIETNGNDALILELNSETDFVAKNEGFQTLIKELAAHLLTNKPANVEEAMAQTMENGKKVEEHINEAIAKIGEKLTLRRFEIVSKTDADAFGAYLHMGGRIGVLTVLEGSTDEAAAKDVAMHIAAVNPKYIDRDAVTAEEVEHERQVLTQQALNEGKPEKIVAKMVEGRLGKFFEEICLLDQAFVKNPDMKVRQFVESKGGTLKGFVRYAVGEGIEKREDNFAEEVMNQVKGSN",
    "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIQMQSILQVADNTGARSLMCIKVLGGSKRRYAGIGDIIKVSVKDVAPRGRVKKGEVYNAVVVRTSKGVRRADGSLIKFDGNAAVLLNAKLEPIGTRIFGPVTRELRTARFMKIVSLAPEVL",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNNRDNLHRFLFEEAKIRGELVQLDASWRAVLACHDYPAVVQSQLGQALAATILLSATIKFKGSLILQTQSEGPLQTLVAQATHHRTLRGLARWDGDVPHGSLSETYGSGRLALTIQTEGKNPYQGIVSLEGVNLAEALQTYFSRSEQLRTRLWLVADEQQAVGLFLQELPSQQGHKTDWERIALLASTVTTQEMLSLPSTELLYRLFNEEQVRLFEPEPVSFRCGCSRGRIEQTLAALGREEMESILKEQGIIEVDCEFCNRHYNFDRVDMEQLFTEQVKAPVTSTRH",
    "output": "Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNLHEYQAKQLFASYGLPVPRGEVAYNVEDALLVASQLSTSRWVVKAQVHAGGRGKAGGVKLVSSKDELAAVAKSMLGTRLVTYQTDARGQPVNAILVEETCEIDKELYLGAVVDRSTRRVVIMASTEGGVEIEKVAHETPEKIFKVVVDPLVGVMPFQCRETAFKLGLKDDQIKQFTHLMMGLGKMFVDCDLSLLEINPLVITKSGQLICLDGKINIDGNALFRQPKLKNMRDVSQEDDRENRASDWELNYIPLDGTIGCMVNGAGLAMATMDVIKLHGGEPANFLDVGGGATKERVSEALKIIVSDEKVKGILVNIFGGIVRCDLIADGILAAVKEVDVKIPVVVRLEGNNAQLGAEILNKSNLNVIAATSLTDAAKKIVAAVSE",
    "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPSLKDVKVKIAGVKKTKQITKAMNMVASAKLRGAQQRIERFRPYAEKFYGMLGDLASKADGSAHPLLEVRDEIKTCGIVLATSDRGLCGSFNANLISTALKLAKQKAAEGKTVKFYCVGKKGRDTIRKADFEVVTAIADQMGSFDFQLANKLGLEVINHYLTGELDEVVLVYGEFVSTAKQLPITLPILPIASEKKDEAEAAPSKEYIYEPAVEGLLAELLPRFIKVQIYRGLLDTSASEHAARMAAMDNATRSCDDMIGALTLLFNKTRQASITRDLMDIVGGAEALKG",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPKDKAVGIQVSQVSKQFGSFQAVKDVDLTVETGSLVALLGPSGSGKSTLLRLIAGLEQPDSGRIFLTGRDATNESVRDRQIGFVFQHYALFKHLTVRKNIAFGLELRKHTKEKVRARVEELLELVQLTGLGDRYPSQLSGGQRQRVALARALAVQPQVLLLDEPFGALDAKVRKDLRSWLRKLHDEVHVTTVFVTHDQEEAMEVADQIVVMNHGKVEQIGSPAEIYDNPATPFVMSFIGPVNVLPNSSHIFQAGGLDTPHPEVFLRPHDIEIAIDPIPETVPARIDRIVHLGWEVQAEVRLEDGQVLVAHLPRDRYRDLQLEPEQQVFVRPKQARSFPLNYSI",
    "output": "Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPLMLTKVEVELEAQPEHNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKAE",
    "output": "Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSELSIYSEQGGEPVFSTLDSARIQHELSLRGIAFDRCASKAEIALDADQADILSTYAEEIHRIQALGDYPTVDAIRMKPDHPDRQALRQKFLSEHTHAEDEVRLFVEGRGLFCLHIKSEVLQVTCETNDWISVPAGTRHWFDMGEKPYFCAIRFFNNPNGWVANFTNDPIAERFSKLRD",
    "output": "Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGKTPEDFERHTMRSLIFVLALSVFTCSGFPVYDYELPVTEEALNASIARINSQTWGPNLYGVVRSHVRHVDMWNSNDYRLELQLSIRETECTKASGRDPFTCGFKVGPFVPTAVCKSVVEVSSEQIVNVIVRCHQSTFSSESMSSEEMTYMLMTDPRKRGSSRSEAFSSRGRGHSNGDWRKPDYTSPGKVE",
    "output": "Could coordinate an aspect of bone turnover."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTATAPVKTEYEAVIGLETHVQLGTATKIFSNASTEFGADPNTHIDPVVLGLPGTLPVLNQKVLEYAVKAGLALNCQIAPYSKFDRKQYFYPDLPKNYQISQYDLPIAEHGWIEIEVAEKGKEPYTKKIGVTRLHMEEDAGKLVHAGSDRLAGSTHSLVDYNRAGVALAEIVSEPDLRTGKEAAEYAQELRRIMRYLGVSDGNMAEGSLRCDVNISIRPKGTEKFGTKVEIKYMNSFNAIQRAIEFEIERQIRCLETGEPIVQETRLWDEGKQVTKSMRSKEGSSDYRYFPEPDLGPIEVSETQRETWRSELPELPAQKRHRYAEQYGLSAYDARVLTDEKSTADYYEATVAAGADAKQAANWLMGDIAAYVNANKLLVSDLPLQPQDLAELVNLIEAGTISGKIAKEILPELLEKGGSPKAIVEAKGLTQISDPAQIEALVDELLAAHPTELEQFRAGKTKLQGFFVGQLMKKTGGRVDPKLSNQILNQKLKG",
    "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAEGKGFLRLEWARDHMPVIAEIRKRFLDEKPFKGINIAMALHVEAKTGIFSLLLKEGGANVRMASCNPLSSDDSVVESLKTDYGMPVFARKGETQEEYYENLQRTLEKPPDIIIDDGGDLTKLVHTERKDLSKNIMGGNEETTTGVVRLKAMEKAGVLLFPMFDVNDANMKHLFDNRYGTGQSTLDGIMNSTNLLIAGRNVVVAGYGYCGRGIAMRLKGMGANVIVTEIDPIKANEAIMDGFQVRRMNDAIRYADMVITATGMKDVVKYEDALVAKKNIVLANAGHFDNEVAVKEIEKHSLEKREVREFVKRYRLENGNTVDVIADGRLVNLAAGQGHPVEIMDLSFALQALTAEYLVKNHQNLEKKVYPVPPEIDRYVAEIRLKQFGGELDTLTEDQIKYLNSWDEGT",
    "output": "May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARKSLMVKAERQPKFKVRKYTRCQICGRVHAVLRKYKICRICFRELAHEGKIPGVKKASW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAGNAVDNANHLTYFFGNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHNRKAHHYTIERELNGTYAISGGRAHASPADLCHYHSQEPEGLVCLLKKPFNRPPGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGNISRDESEQTVLIGSKTNGKFLIRARDNNGSFALCLLHEGKVLHYRIDRDKTGKLSIPEGKKFDTLWQLVEHYSYKPDGLLRVLTVPCQKIGVQMGHPGSSNAHPVTWSPGGIISRIKSYSFPKPGHKKPPPPQGSRPESTVSFNPYEPTGGAWGPDRGLQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAAWGPLNKYLQQNRHIKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYFKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPPGCPREMYDLMFLCWTYDVENRPGFAAVELRLRNYYYDVVN",
    "output": "Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can also be indirect and mediated by adapter proteins containing ITAM or partial hemITAM domains. The phosphorylation of the ITAM domains is generally mediated by SRC subfamily kinases upon engagement of the receptor. More rarely signal transduction via SYK could be ITAM-independent. Direct downstream effectors phosphorylated by SYK include VAV1, PLCG1, PI-3-kinase, LCP2 and BLNK. Initially identified as essential in B-cell receptor (BCR) signaling, it is necessary for the maturation of B-cells most probably at the pro-B to pre-B transition. Activated upon BCR engagement, it phosphorylates and activates BLNK an adapter linking the activated BCR to downstream signaling adapters and effectors. It also phosphorylates and activates PLCG1 and the PKC signaling pathway. It also phosphorylates BTK and regulates its activity in B-cell antigen receptor (BCR)-coupled signaling. In addition to its function downstream of BCR also plays a role in T-cell receptor signaling. Plays also a crucial role in the innate immune response to fungal, bacterial and viral pathogens. It is for instance activated by the membrane lectin CLEC7A. Upon stimulation by fungal proteins, CLEC7A together with SYK activates immune cells inducing the production of ROS. Also activates the inflammasome and NF-kappa-B-mediated transcription of chemokines and cytokines in presence of pathogens. Regulates neutrophil degranulation and phagocytosis through activation of the MAPK signaling cascade. Required for the stimulation of neutrophil phagocytosis by IL15 (By similarity). Also mediates the activation of dendritic cells by cell necrosis stimuli. Also involved in mast cells activation. Involved in interleukin-3/IL3-mediated signaling pathway in basophils (By similarity). Also functions downstream of receptors mediating cell adhesion. Relays for instance, integrin-mediated neutrophils and macrophages activation and P-selectin receptor/SELPG-mediated recruitment of leukocytes to inflammatory loci. Also plays a role in non-immune processes. It is for instance involved in vascular development where it may regulate blood and lymphatic vascular separation. It is also required for osteoclast development and function. Functions in the activation of platelets by collagen, mediating PLCG2 phosphorylation and activation. May be coupled to the collagen receptor by the ITAM domain-containing FCER1G. Also activated by the membrane lectin CLEC1B that is required for activation of platelets by PDPN/podoplanin. Involved in platelet adhesion being activated by ITGB3 engaged by fibrinogen. Together with CEACAM20, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTASELVAGDLAGGRAPGALPLDTTWHRPGWTIGELEAAKAGRTISVVLPALNEEATIESVIDSISPLVDGLVDELIVLDSGSTDDTEIRAIASGARVVSREQALPEVPVRPGKGEALWRSLAATSGDIVVFIDSDLINPHPLFVPWLVGPLLTGEGIQLVKSFYRRPLQVSDVTSGVCATGGGRVTELVARPLLAALRPELGCVLQPLSGEYAASRELLTSLPFAPGYGVEIGLLIDTFDRLGLDAIAQVNLGVRAHRNRPLDELGAMSRQVIATLLSRCGIPDSGVGLTQFLPGGPDDSDYTRHTWPVSLVDRPPMKVMRPR",
    "output": "Involved in the biosynthesis of 6-O-methylglucose lipopolysaccarides (MGLPs). Catalyzes the transfer of the glucose moiety from UDP-alpha-D-glucose (UDP-Glc) to the position 2 of 3-phospho-D-glycerate (3-PGA) to form glucosyl-3-phosphoglycerate (GPG)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSFTPGKQSSSRASSGNRSGNGILKWADQSDQSRNVQTRGRRAQPKQTATSQQPSAGNVVPYYSWFSGITQFQKGKEFEFAEGQGVPIAPGVPATEAKGYWYRHNRRSFKTADGNQRQLLPRWYFYYLGTGPHAKDQYGTDIDGVFWVASNQADVNTPADILDRDPSSDEAIPTRFPPGTVLPQGYYIEGSGRSAPNSRSTSRTSSRASSAGSRSRANSGNRTPTSGVTPDMADQIASLVLAKLGKDATKPQQVTKQTAKEIRQKILNKPRQKRSPNKQCTVQQCFGKRGPNQNFGGGEMLKLGTSDPQFPILAELAPTAGAFFFGSRLELAKVQNLSGNLDEPQKDVYELRYNGAIRFDSTLSGFETIMKVLNENLNAYQQQDGMMNMSPKPQRQRGQKNGQGENDNISVAAPKSRVQQNKSRELTAEDISLLKKMDEPFTEDTSEI",
    "output": "Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVQLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMMNTDLSRILKSPEIQRALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVKKLEAAATALATKSEKVVPEKGTADKKPAVGKKGKKVDAKKQKPAGKKVVAKKPAEKKPTTEEKKPAA",
    "output": "Component of the large ribosomal subunit . The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDRLTLLRPDDWHIHLRDGAVLQHTVGDVARTFARAIIMPNLVPPVRNALEAGGYRERILAARPAGSRFEPLMVLYLTDRTSPEDIRAAKASGFVYAAKLYPAGATTNSDSGVTSIDNIFPAIEALAETGMPLLVHGEVTRSEIDVFDREKRFIDEHMRRLVERFPTLKVVFEHITTADAAQFVTEAPANVGATITAQHLLYNRNHMLVGGIRPHFYCLPILKRNTHQVALLDAATSGNPKFFLGTDSAPHAKHAKEAACGCAGCYTAYAAIELYAEAFEQRNALDKLEGFASKHGPDFYGLPRNTDTITLVRDEWTAPDSLPFGDNTVIPLRAGEKLRWRLLEDNA",
    "output": "Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPTVLIVGKSNVGKSTLFNKLIGYKKSIVDDKEGVTRDAVSGRVSYYSKTFNIVDTGGIFENPEDDIINKSKDLTLKMLNEADLILFVIDAKNGITSEDYYLADIIRKSNNDVILVSNKSESERRVQNNLPDIYKLGFGDPIFVSAEQGKNIDTLIERIVNVLESKGLSLEENLKEESQSIIRVSFIGRPNAGKSTLFNSILNKERVLVTPIPGTTRDSVDELVTINGRKYLFVDTAGLRRKSKVDYKSLDMYSNVRSIKSIENSDVVVILIDAIEGITHQDQRIAGIAENRGKATIVAFNKIDLIKNFKYKKEEFIDQFNEKLYFINYSPLIFLSAINKKGIDNLINAIDEAYKSLHYRVQTSAVNSAIQRMMAFTPPPKGLKILYGTQVDIRPPTFLFFTNGKKVPEFYQNHIRKTIRENIYPFVGAPIFLKFKSRH",
    "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAQIRIHEVNTRIENEVEVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVFSKEIADVSVRRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY",
    "output": "Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEWETVIGLEIHAQLNTKSKIFSAASTQYGQKPNSQACAVDLGLPGVLPVLNVEVINKAIKFGVAINAHINQRSIFDRKNYFYPDLPKGYQISQMDRPIVGEGKIEITFDDQTKIVGITRAHLEEDAGKSMHDMFDDDTAIDFNRAGIPLLEIVSEPDMRSAKEAVIYAKKIHALVQYIDICDGNMQEGSFRFDANVSIRPKGEKELGTRTELKNINSFKFLERAINLEVERQQDILEESGSIVQETRLYDSVKHETRSMRSKEETNNYRYFPDPDLLSVEISNELLEKIRQTLPELPTQKKARFVSELGLSDYDADVLTLQKPLADYFETMLEHHASNAKLCANWIMGELSASLNKHKIDIQNSPITAQALSLLISRISDDTISGKAAKDVFKAMWNSEGNADEIIQAKGLKQMIGMGEIEAIVEQVIANNARQAVQFKLGNDKIFGFFVGQIMKLTAGKANPKQVNELLRNKLF",
    "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTYSTESLAQSDIWPATADVSTLRRKLLDLLCQLAYKEGDFVLSSGQPSSYYINGKQVTLHPQGALAIGRILLSLLPSDTQAVAGLTLGADPIVTAVSVVSAYENRPIPALIIRKEAKGHGTKAYIEGPNLPEGAKVVVLEDVVTTGQSAMKAVDRLRAAGYVVDEVISLVDRQQGGAEFYQSVGLKFEAVFTIMDLQQRYQELGN",
    "output": "Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSGGLLKALRSDSYVELSEYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYREDYDAGRGGYGKLAQKQ",
    "output": "Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC) via its interaction with UPF1, promoting the interaction between UPF1 and UPF2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with SRRT/ARS2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of PARN, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, NCBP2/CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires NCBP1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAFENLKISRHISSSTKNLLKAKKIMAALASNPQMLTRQAHGNKKEQLWRKESLNLEKKCGFCVSVYSNEKLGRSHMEKEWRLKAFWSNIAQPTTLEMEPINNVEELDAVLSHARQLSQPIIIEWMASWCRKCIYLKPKLEKLAAEYNNRAKFYYVDVNKVPQTLVKRGNISKMPTIQLWKEDEMKEEVIGGHKGWLVIEEVRELINKFV",
    "output": "Probable thiol-disulfide oxidoreductase that may participate in various redox reactions."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSGNNHPGDASAEIDVVLVTGLSGAGRGTAAKVLEDLGWYVADNLPPQLITWMVDFGLAAGSRITQLAVVMDVRSRGFTGDLDSVRRELATRNIIPRVVFMEASDDMLVRRYEQNRRSHPLQGEQTLAEGIAAERRMLAPVRATADLIIDTSALSVPGLRESIERAFGGDASATTSVTVESFGFKYGLPMDADIVMDVRFLPNPHWVDELRSLTGQHSAVRDYVLGQPGAAEFLRTYRRLLSLVVDGYRREGKRYMTVAIGCTGGKHRSVAIAEALMGLLQSDLQLSVRVLHRDLGRE",
    "output": "Displays ATPase and GTPase activities."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDSTFSAKNLACVRGGRVVFAGLGFSLSAGGALVLLGPNGSGKSSLLRVLAGLLKPAHGLLAWNGEALAEDPEAHAARTHYLGHHDAVKPVLSVAENLRFWAHLHDPHAERAGRAVDAALSRFGLARLATIPGKMLSAGQKRRTNLARLLAAPSPLWLLDEPTTALDKASIKVLEDVLAEHRAAGGMVVLSTHADINMPGAQELHLDQFAVAEELP",
    "output": "Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAISSTERRAKNVQIFVEKDAVETSFAKWAQPGHFSRTLAKGPKTTTWIWNLHADAHDFDSQTSSLEEVSRKIFSAHFGQLAVIFLWISGMHFHGAYFSNYSAWLSDPISIKQSSQVVWPIVGQEILNADVGGNFQGVQTTSGWFQMWRAEGITSEVELYWIAIGGLIMSALMLFAGWFHYHKAAPKLEWFQNAESMMNHHLAGLLGLGCLSWSGHQIHIALPINKLLDAGVAPQEIPLPHEFLINRELMAQLYPSFNKGLAPFFSGQWGEYSDFLTFKGGLNPVTGGLWLSDIAHHHLALSVLFIFAGHMYRTNWGIGHSMKEILEAHKGPFTGEGHKGLYEILTTSWHAQLAINLAMMGSLSIIVAHHMYAMPPYPYIATDYATQLSLFTHHMWIGGFCVVGGAAHGAIFMVRDYTPANNYNNLLDRVLRHRDAIISHLNWVCIFLGCHSFGLYIHNDTMRALGRPQDMFSDKAIQLQPIFAQWVQNIHLLAPGTTAPNALATTSYAFGGDVVEVGGKIAMMPIKLGTADFMVHHIHAFTIHVTVLILLKGVLYARSSKLIPDKANLGFRFPCDGPGRGGTCQSSSWDHVFLGLFWMYNSISVVIFHFSWKMQSDVWGTITPDGNISHITGGNFAQSSITINGWLRDFLWSQASQVIQSYGSASSAYGLIFLGAHFIWAFSLMFLFSGRGYWQELIESIVWAHNKLNFAPAIQPRALSITQGRAVGLAHYLLGGIGTTWSFFLARAISIT",
    "output": "PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVHFTAEEKAVITSLWGKVNVEEAGGEALGRLLVVYPWTQRFFDNFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKNMDDLKGTFAHLSELHCDRLHVDPENFKLLGNELVIVLAKYFGKEFTPQVQAAWQKMVAGVAIALAHKYH",
    "output": "Gamma chains make up the fetal hemoglobin F, in combination with alpha chains."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTYTISIRVYQTTPKGFFRPVERTNWKYANGGTWDEVRGEYVLTMGGSGTSGSLRFVSSDTDESFVATFGVHNYKRWCDIVTNLTNEQTALVINQEYYGVPIRDQARENQLTSYNVANAKGRRFAIEYTVTEGDNLKANLIIG",
    "output": "Lectin that recognizes O-linked galactose-beta-1,3-N-acetylgalactosamine, a disaccharide (Thomsen-Friedenreich antigen or T-disaccharide), present on cell surface glycoproteins. Can also bind galactose-beta-1,3-N-acetylglucosamine. Does not bind monosaccharides. Can be internalized by clathrin-coated vesicles after binding to surface glycoproteins. After internalization it inhibits nuclear import of nuclear localization signal dependent proteins. Inhibits proliferation of malignant cells without cytotoxicity for normal cells."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKTLYLRNVPDDVVERLERLAELAKTSVSAVAVRELTEASRRADNPALLGDLPDIGIDTTELIGGIDAERAGR",
    "output": "Antitoxin component of a possible type II toxin-antitoxin (TA) system. The cognate toxin is VapC9 (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVKSQRNGKKGAKVLSRKEKRQSEKEEMDSLRQRIEEYNPEVDEASIKHFSDLPITQNTLRGLKECSFVSLTDIQKKSIPVALKGEDLMGTARTGSGKTLAFLIPVIEILLRNDITEYDGLAALIVSPTRELAVQIFEVLAKIGKYNSFSAGLVTGGKDVQYEKERISRMNILVGTPGRISQHLNESVGMETSNLQVLVLDEADRCLDMGFRKQIDNILNHLPRTRQTLLFSATHTDSVQDLARLSLTNPKRIGTSSDQDISAIPESLDQYYVKVPLNEKLDVLWSFIKSHLKSKILVFFSSSKQVQYAYETFRTLQPGIPLMKLYGRHKQTSRLETTVKFSQAQHACLFATDIVARGLDFPAIDWVIQVDCPEDVATYVHRVGRSARFGRQGKSLLMLLPTEEDGMLKRMKVHKIEPKMMNIKEKSKKSIRPQLQSLCFKDPVIKNLGQRAFIAYFRSVYIQKDKDIFKVDELPVEEYAASLGLPGAPKIKIKGGEINKEKKNQSRKLLQLSKADENGELKEDDDKPAKVRTKYDRIFDRKNQTILSEHYLNMTKSAHGGKDDDEDEDFMTVKRQDHELVDDELPDLLLPVSKRQAKKALSRKATLASKGNPTKLKFDDDGVPHAIYELEGEEDFEKAGDAKQQKMEFVQKEQEAMKITDLADREVERQKRQEKKRKRKEIERRIREEEWDDGSGMDGEDLPDLERDMEPTEAKPKRTSNWFDDDDDDNDGGDEKHGNGKPPVKKAKSDSKYVEFEEPETLEDLESLAATLIGN",
    "output": "ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSNPPQGSSLASPIQAAAVTGDKTTLLRLIASSPQVIDQEDQLGRTPLMYSVLGDRRSCAEALLKHGAKVNRPDRSGRTALHLAAQTGNHRLLKLLLSRKADCTHRDLCDITALHLSTRHQDTQCLVLLLKYTPPGQVDAQDQRKQTALHWSAYYNRPQHVRLLVRHGSNIGIPDTEGKIPLHWAAGHKDPEAALTVRCLFEAAPTESLLNWQDYEGRTPLHLAVGDGNQEVVRLLTSYRGCNVAPYDNLFRTPLHWAALLGHTPIAHLLLERNNSPNIPSDSQGATPLHYAAQGNCPDTVRVLLSHPSVRDEADLEGRTALMWAAGKGSDEVVRTMLELNPKLEVNRTDKYGGTALHAASLSGQITTVRILLENRAQADAVDVMKHTPLFRACEMGHREVIATLIKGGAKVHLVDKDGRSPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKADPNIQDKNGRTALHWSCNNGYLDAVKLLLGYNAFPNQMENTEERYTPLDYALLGGHQEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGHKVRRAFQERKNLLMKHEQLRKGAAAKKREGENRQKVKVGQTKGKQKDADSMERQNKSNEQIIKNEVVHEWQGEASGNAEDRKGKHREENLETNHLQHSKHMAKNQRITAQIQSSPSEHEHTNSIQIRTSPSGTSNTQSSPLGNEIPKNMYWDDNPSQKHTQTRRTSRHQMESPDVVVHRIEDLIQKESRRKSHREERKGSHRQRQSSDYRLHTSEKEASDSAIHREEEGKKKETKKGRRTVAVTPKIEACCKGGCGKLSQSEKVSLGIGIQGRVDCITSPEPCETPSRVCRERKTISAKTGQRPLTETHKPPGKACRSSSALKSSLPSHIKQTAIDSKCLDSTLSYIGFGEAIKPLFPMGILREGSFFSKWQNIDIELIPVQARLQLVEREKARKQLFQRKNHAATVIQKAWRTYWVRKSSCKTRHSRSQNNPPAMV",
    "output": "Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Plays a central role in convergent extension movements in gastrulating embryos, a processus regulated by Wnt signaling (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDLSNLTLTKIQELVLTRKCKIYDILLAYKNNYELNKDINGYIEFFDDSLEIAKRYDDCLKNCELEDLPLIGMLIAVKDNISIQDKSLTCASEILKGYISPYDATVIKRLKNKGAILIGRTNMDEFAMGSTCEFSYYGATLNPLNREYVIGGSSGGSAAVVAAFQAPFSLGSDTGGSVRLPASFSGILGFKPSYGGLSRYGLASYASSFDQIGFFSHSIEDIALILKHTCGSDKMDSTSVDIFDDFYPLKIESLQGKNLAVIKELSEDLMDKNVANSFAKFKLDLLSKGINIKEVSIEEINFILSIYYIISPVEASSNLARYTGLCYGKRISEGLSLNDFYFKHRSNFLSEEVKRRIVLGNYLLSERYDSKYYAKACEILQNLIIPKFNKLFESCDFIITPTSFVKPFRLGLDFDDPVKMYYSDICTVIANLIGAPAISLPYSKDEEGLSIGMQIIGRSKKDFELLSFSKNVIRELGLNGI",
    "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLKKCVWLAVALCLCLWQFTMGTALAAELTPEVLTVPLNSEGKTITLTEKQYLEGKRLFQYACASCHVGGITKTNPSLDLRTETLALATPPRDNIEGLVDYMKNPTTYDGEQEIAEVHPSLRSADIFPKMRNLTEKDLVAIAGHILVEPKILGDKWGGGKVYY",
    "output": "Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II. It is not essential for growth under normal conditions but is required under low CO(2) concentrations. PSII is a light-driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating a proton gradient subsequently used for ATP formation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATLMDKLITSVAPPSTKPNNKVTVVGVGQVGMACAISILEKGLCDELALVDVVEDKLKGEMMDLQHGSLFLNTHKIVADKDYSVTANSKVVVVTAGVRQQEGESRLDLVQRNVNVFKFIIPQVVKHSPDCIILVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRFLMAEKLGVHPTSCHGWILGEHGDSSVAVWSGVNVAGVSLQEMNPAMGSDQDPESWKQVHKQVVDSAYEVIKLKGYTNWAIGMSVADLLETILKNLCRVHPVSTMVKGMYGIENEVFLSLPCVLGSAGLTSVINQKLKDNEVAQLQNSATTLWNVQKDIKDLKS",
    "output": "Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFITRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSTVEAGAGTGWTVYPPLAGNLAHAGASVDLAIFSLHLAGVSSILGAINFITTIINMKPPALTQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPALLWALGFIFLFTIGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFTGYTLNDLWAKIHFSIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTTWNIISSIGSFISLTAVILMVFIIWEAFASKREVATVELTTTNIEWLYGCPPPYHTFEQPVFVKV",
    "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIQTQSMLDVADNSGARRVMCIKVLGGSHRRYAGIGDIIKVTVKEAIPRGKVKKGQVMTAVVVRTRHGVRRADGSIIRFDGNAAVLLNNKQEPIGTRIFGPVTRELRTEKFMKIVSLAPEVL",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRVYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRIRLSIKEATEQSQPAAAPEAPAAEQGE",
    "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MALVEGNNGVSGGAVSFSEEQEALVLKSWAIMKKDSANIGLRFFLKIFEVAPSASQMFSFLRNSDVPLEKNPKLKTHAMSVFVMTCEAAAQLRKAGKVTVRDTTLKRLGATHFKYGVGDAHFEVTRFALLETIKEAVPVDMWSPAMKSAWSEAYNQLVAAIKQEMKPAE",
    "output": "May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDSLNVQKAYDVKDTAVTTKAYANNGTTLDVSGLDDAAIKAATGGTNGTASVTGGAVKFDADNNKYFVTIGGFTGADAAKNGDYEVNVATDGTVTLAAGATKTTMPAGATTKTEVQELKDTPAVVSADAKNALIAGGVDATDANGAELVKMSYTDKNGKTIEGGYALKAGDKYYAADYDEATGAIKAKTTSYTAADGTTKTAANQLGGVDGKTEVVTIDGKTYNASKAAGHDFKAQPELAEAAAKTTENPLQKIDAALAQVDALRSDLGAVQNRFNSAITNLGNTVNNLSEARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR",
    "output": "Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFGSEQSKVIFCEADDWKPFYEAYGSQFEDIEIEMDRRNSAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIEPPSASPVIIEDDVLIGANAVILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQASEVQDTKKEIVAALRKLND",
    "output": "Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MILKSFILGNLVSLCMKIINSVVVVGLYYGFLTTFSMGPSYLFLLRARVIEEGEEGTEKKVSATTGFITGQLMMFISIYYAPLHLALGRPHTITVLALPYLLFHFFWNNHKHFFDYGSTTRNSMRNLSIQCVFLNNLIFQLFNHFILPSSMLVRLVNIYMFRCNNKMLFVTSSFVGWLIGHILFMKWVGLILVWIQQNNSLRSNKYIRSNKYLVSELRNSMARIFSILLFITCVYSLGRIPSPIFTKKLKETSETEEREEETDVEIETTPETKGTKQEQEGSTEEDPSSSLFSEEKENPDKIDETEEIRVNGKEKTKDEFHFHFKETCYKNRPVYETFYLDGNQENSKLEIFLDKKDKDLVWFEKPRVTILFDYKRWNRPFRYIKNDQFKNAVRKEMSQYFFSTCRSDGKERISFTYPPSLSTFLEMIQRKMSLFTTEKLSSDELYNHWNYNNEQKKKNLSNEFINRVEVLDKGFRVLNILEKKTRLCNDETKKEYLPKIYDPFLSGLYRGKVNFFFSPSIINEISIKNYIEMLWINKIYLILLISNYQEFEPKMEDRIRILKFLFDAIIVDSKNKKIVKKSTEIKKEISKQIPRWSYKLIDDLEQQEGENEENAAEDHEIRSRKAKRVVIFTDNQENPDSNTYNNSKTKDTTNFDQTGEVALIRYSQQSDFRRDIIKGSMRTQRRKIAILKLFQANLHSPLFLDRIDKFLFFAFDTSELMKIMFINWMCKNAEFTISDSTSTYTEEKTKESDKKEKEEIKNRREEDKREEKVRIEIAETWDSIIFAQAIRGCVLVIQSILRKYILLPSLIIAKNIIRMLLFQIPEWSEDLKDWNREMHVKCTYNGVQLSETEFPKNWLTDGIQIKILFPFRLQPWHRSKFKFLSKDPIKKKRQKNDFCFLTVWGMEAELPFGSPRKELSLFEPIFKKLKKKIRKLKKNGFLTLTILKEKRKLFLHLPKETKNWFIKGILFLKEIINKFSKSKRNPILLFGFREVYELNETKNEKNSPINNRTIHKFSTSIRSMDWINYSLTEKKMKDLNARTKTIRNQIEKITKEKKKRFLISERNISPNKLSYNAKRLKLKSSKNILQILKRNNAQLVRKSYFFIKILIEKIYIDILLAIINIPRINVQFFLESPRKMINKYIYMYNKKENHKRIEKTNQNTLIHFISIIKKALNYSNFNKNSKIFYNITSLSQAYVFYKLSQVQVINLYKLRSVFQYHGASLFLKNEIKDYFGVQGRFQFKLKDTNFRNSVMNEWKNWVRSTYQYKYDLSQIRWSSLISQKWRNRMNQQHMIQNKDLNKWNLYDKDQLIHYEKQNNFEVDSLSNQKDNFKKYYRYNILLYKSINYEDKKDSSIYELPFQLNNKQELFYNYKIDKRKLFDMSGGIPVNKHLTEDDIIDTEKSSHRKYLDWRILHFGLRKKVDIESWIDTGTKQKKNLFDWMGMNEEILDRPTSNLEFWFFPKFVILCNAYKIKSWVIPIKLLFLNFNGTKNVSENKKINKKKNNDPFISISSNETKSIQLKNQNHEEKESEDQVDLESVLVNQEKDVEEDYVRSDRKERRKKKQYKSNTEAELDFLLKRYLCFQLRWDDSLNQKIINNIKIYCLLLRLTNPREIIISSIQRGELSLDILMIQKDLTLTELMKKGILIIESTRLSVKNDGKFIMYQTINILLVHKRKQQINQRYRKKNYIDKKNFNESIVINQSLTRNKDKNNYDLPVPENLLSSKHRRELRILISFNSKNGNDINTEIINNNNIKNHAHIIDKRKHFDRDKNKLIKLKLFLWPNYRLEDLACINRYWFDTNNASRFSMIRIHICPRLKSR",
    "output": "Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVYPRYKKWCDDYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV",
    "output": "Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKDQLLVPLRRRPWTCRKCLQRLQLLPQHQTRRSFETAASPFPRQLDSLPADYSRTKTVDDDTLRRVFDSQQFWREFSQQRSAQPKPTGLVQNQYLTSPDGFRTFANVSLQKCQAIVSKVLAASTLEEYRTMARDLDRLSDLLCRVIDLSDFIRVIHPDPQVQEAATQAYALMFEYMNVLNTTTGLNDQLKKAAANPEVTSQWSDEEKIVAQILIKDFSNSAIHMPPHERQRFVNLSNDISQLGSSFVNGAEPAKSHVSVATNNLRGLDPILVQQIKRWNRTAAVPTTGMIPRLALRSVHDENVRREVYLASRTSSKRQLHRLEELLLKRAELAKLSGYESFAHMTLSDKMAKSPEAVSNFLTALVDSNRKLVREELSQLQAMKGAPLQPWDHAYYVHQRVMQYSQARRSRELSAVPEFFSLGTVMQGLSRLFDRLYGVRLVPQEPAPGETWNPDVRRLDVVDESGRHIAVIYCDLFSRPNKHPNPAHFTLRCSREISTEEVAECASLDQSSHPNDGMATAVDPVTKTLRQLPTIALVCDFSEPGTNGGGRPSLLSEHSVRTLFHEMGHAVHSILGQTRLQSISGTRCATDFAELPSVLMEHFATAPSVLALYARHWRTDEPLSEGMIRSMERDRTAHGSIYGAVENEAQILMALVDQAYHSRPADGGRIDSTALYQQVSQQHSSLPEPADVTPPTSWQGFFGHLYGYGATYYSYIFDRAIANKLWVDVFGAGRQAVDRAAGERYKNEVLRWGGGRSGWECVAGALGSANESNADGRLVEGGDEAMREVGRWGLGRDGVSG",
    "output": "Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRTPCSQHRRDRPSAIGSQLPDADTLDTRQPPLQEIPISSFADKTFTAPAQIRNFCIIAHIDHGKSTLADRMLQLTGVVDERSMRAQYLDRMDIERERGITIKAQNVRLPWRVDKTDYVLHLIDTPGHVDFTYEVSRALEACEGAVLLVDAAQGIEAQTLANLYLALDRDLHIIPVLNKIDLPAADPDRYAAEMAHIIGCEPAEVLRVSGKTGEGVSDLLDEVVRQVPPPQGDAEAPTRAMIFDSVYDIYRGVVTYVRVVDGKISPRERIMMMSTGATHELLEVGIVSPEPKPCEGLGVGEVGYLITGVKDVRQSKVGDTVTSLSRARGAAAEALTGYREPKPMVYSGLYPVDGSDYPNLRDALDKLQLNDAALTYEPETSVALGFGFRCGFLGLLHMEITRERLEREFGLDLISTSPNVVYRVHKDDGTEIRVTNPSDWPEGKIRTVYEPVVKTTIIAPSEFIGTIMELCQSRRGELGGMDYLSPERVELRYTMPLGEIIFDFFDALKSRTRGYASLDYEEAGEQEAALVKVDILLQGEAVDAFSAIVHKDTAYAYGNKMTTKLKELIPRQQFEVPVQAAIGSKIIARENIRAIRKDVLSKCYGGDITRKRKLLEKQKEGKKRMKTIGRVEVPQEAFVAALSTDAAGDKGKK",
    "output": "Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKTKDQRTAKTLEKTWDTLNHLLFISSCLYKLNLKSIAQITLSILAMIISTSLIIAAIIFIASANNKVTLTTAIIQDATSQIKNTTPTYLTQNPQLGISFFNLSGTTSQTTAILALTTPSVESILQSTTVKTKNTTTTQIQPSKPTTKQRQNKPPNKPNNDFHFEVFNFVPCSICSNNPTCWAICKRIPSKKPGKKTTTKPTKKPTIKTTKKDHKPQTTKPKEAPSTKPTEKPTINITKPNIRTTLLTNSTTGNLEHTSQEETLHSTSSEGNTSPSQVYTTSEYLSQPTSPSNITNQ",
    "output": "[Isoform Membrane-bound glycoprotein G]: Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMGRDYALYFFAALGSFLVVYIVLPIVTIFAKQALDFEMLVKTVHDPLVLEALRNSLLTATATALISLFFGVPLGYILARKDFRGKNFVQAIIDVPVVIPHSVVGIMLLVTFSNAILDSYKGIIAAMLFVSAPFAINSARDGFLAVDEKLEHVARTLGASRIRTFFSISLPMALPSIASGGIMAWARSMSEVGAILIVAYYPKTAQILVMEYFNNYGLRASRPISVMLMLISLSIFVFLRWLIGRVRE",
    "output": "Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEKFEGYSEKLKFPRQYFVYPLLFQEYIYVFAHDYGLNGSELVEIIGSNNKKFSSLLVKRLMIRMYQQNFWINLVNHPNQDRLLDYNNFFYSEFYSQILSEGFAIVVEIPFSLREQSCPEEKEIPKFQNLRSIHSIFPFLEDKFLHLHYLAHIEIPYPIHLDILLQLLQYRIQDVPSLHLLRFFLNYYSNWNSFITSMKSIFILKKENKRLFRFLYNSYVSEYEFFLLFLRKQSSCLRLTSSGTFLERIIFSRKMEHFGLMYPAFFRKTIWFVMDPLMHYVRYQGKAILASKGTLLLKKKWKCYLVRLWQYSFSFWTQPQRIHLNQLENSCFDFLGYFSSVPINSLLVRNQMLENSFLIDTQMKKFDTKVPVTPLIGSLAKAQFCTGSGHPISKPIWTDLSDWDILDRFGRICRNLFHYYSGSSKKKTLYRLKYILRLSCARTLARKHKSTVRAFMQWLGSVFLEEFFTEEEQVFSLMFAKTTYFSFRGSHSERIWYLDILRINDLVNPLN",
    "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPIITQILARQILDSRGNPTVEVDVYTESSFGRAAVPSGASTGVHEAVELRDGDAAVYLGKGVLKAVENVNTVINDALTGMLVTEQEEIDQALLDLDGTPNKSKLGANALLGVSMACAKAGAEYSGLPLYRYIGGTMASTLPVPMMNVLNGGAHADNTVDFQEFMIMPAGFDTFSDALRCGAEIFHALKALLKSKGLSTAVGDEGGFAPNLSSNEEAIELVIEAIGKAGYKVGSPTDKGGLGDAQVMIALDPASSEFYDSAKKRYVFKKSSKRELTSLEMAEYWEKWASDYPIISIEDGMAEDDWEGWKVLTEKIGSRVQLVGDDLFVTNSKRLAEGIERGVANSILVKVNQIGTLTETLDAIDLAKRNGYTSVISHRSGETEDSTIAQIAVATNAGQIKTGSLSRSDRMAKYNELLRIEEELGDQARYPGRKAFRV",
    "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSEILNLKDLKVYYPIRSGFFNRVTDNVLAVDGVDLTIHEGETVGLVGESGSGKSTIGKTIVGLEQMTSGQLIYKGQDVSKKKIRNQLKYNKDVQMIFQDAFSSLNPRKTIYDIIAEPIRNFEKIDANTENKRIHELLDIVGLPKQALEQYPFQFSGGQQQRIGIARAVATNPKLIVADEPVSALDLSVQAQVLNFMKLIQKDLGIAFLFISHDLGVVRHMTDNIAVMHNGRIVEKGTRRDIFDEPQHIYTKRLLSAIPSIDVTRRAENRKNRLKVEQDFEDKKANFYDKDGHALPLKKLSESHWAALPKGGENVESNY",
    "output": "Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSWLEKILEKSNIVSSRKASIPEGVWTKCTSCEQVLYYAELERNLEVCPKCDHHMRMKARRRLETFLDQGERVELGEELEPQDKLKFKDSKRYKERLAAAQKASGEKDALVVMKGAVLGVPVVACAFEFSFMGGSMGSVVGARFVRAVEAAIEHNCGLICFSASGGARMQEALMSLMQMAKTSAALERLSDKGLPFISVMTDPTMGGVSASLAMLGDINIGEPKALIGFAGRRVIEQTVREELPEGFQRSEFLLEHGAIDMIVDRRDMRQRVASLLAKMTGQASPLVVSVNDAPNEVPYAVPEANKKG",
    "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MMKPKYERILIKLSGEALAGERGVGIDLKTVQEMAKEIQEVAESGIQIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLKQLGVDTRVQTAIAMQSVAEPYIRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILMAKNGVDGVYNADPKKDANAVKFNELTHREVISRGLKIMDATASTLSMDNDIDLVVFNMNEPGNIKRVVFGEPIGTTVSNSSEEK",
    "output": "Catalyzes the reversible phosphorylation of UMP to UDP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKLSAPLLVSLAAFSQAVTALVAFPGAEGFGANAIGGRNGQVYVVTNLNDSGTGSLRDAVSATDRIVVFAVGGVIKISDRIVVSKRVTILGQTAPGDGITVYGNGWSFSNADDAIVRYIRIRMGKGGSSGKDALGIAEGNRMIFDHVSVSWGRDETFSINGDASNITVQNSIIAQGLETHSCGGLMQTDGGVSLFRNLYIDNKTRNPKVKGVNEFTNNVVYNWGGGGGYIAGDSAGQSYANIIGNYFISGPSTSVTAFTRGNANFHGYVQNNYYDPDKDGQLDGFELGVSSSNYGGVAIMSSKYNYPAVAYTMSPAEAVTYVTKYAGASKVRDSVDTQLIAQVQSWGTEGGLISDEATMGGPGTLNGGTPAKDTDGDGIPDEAEKQLGTDPNTNDSMKLHSSGYTYLEVWANSLVPSTYH",
    "output": "Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAVDAKLIKELREITQAGMMDCKKALEASDNNIDNAIVWLRENGLAKAAKKTDRVAAEGIVLAKENDQKIVILEVNSETDFVAKNEKFLSLVDEIANALLNSNASSLEEGLQVKTDSGLTIEQSLISATATIGEKIALRRFELVNKTSGSSVIYNHANKRVSTLLVFDNKLDPTDAYNVAMHVAAMAPKYINMDQIPEDFKNAEMHIIKEQAKDDAKLQAKPANVLENILKGKLSKRLAEVSLLDQLFVIDESFKVGDFLKSKHVSLVKMIRYEVGEGIEKVVTNFADEVAAQLK",
    "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSQNVIRIATRKSPLALWQAEFVKAELEKFHPDLTVELLPMSTKGDIILDTPLAKVGGKGLFVKELEVAMLENRADIAVHSMKDVPVDFPEGLGLEIICEREDPRDAFVSNNYKSISELPKGAVVGTSSLRRQCQIRAARPDLQIRDLRGNVGTRLGKLDAGTYDAIILAAAGLKRLKLEERITSFISAEESLPANGQGAVGIECRTDDERVKALLAPLEHAETRFRVIAERAMNTHLEGGCQVPIGAYAEIVDDTLTLRGLVGNPDGTQIIASTKVGPKTDAKALGISLAEELLSKGAKTILDAVYIK",
    "output": "Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEKYILEGATGSWEIVVGLEVHAQVISKSKLFSGAATAFGAEPNSQVSLIDAAMPGMLPVVNRECIRQAVRTGLAIGAVINRVSKFDRKNYFYADLPQGYQISQLYHPIVGEGSLLIDVDGEEREIGIERIHVEQDAGKLMHDQHPDKSYVDLNRAGIALMEIVSKPDIRSPAEAGAYIRKLRAILRYVGSCDGNMEEGSMRADVNVSVRKAGEPFGTRCEIKNVNSVRFVQAAIEYEARRQIEVIEDGGEIIQETRLFDHDKGETRSLRSKEDAHDYRYFPDPDLLPLELPESFIDECRESLPELPDTKRQRYITQLNLTPYTASVITADHETAAWFEAMLEYFKAPDAKIATAAANWLTSDLFGALKKLGRDITDSPVSPKQGAELVGLVADGTLSGSLAKQVFEIMLESGQDPAVIVEERGLKQTSDTGAIEEVINKILADNQDKVEQYRSGKDKLFGFFVGQTMRAMGGKANPAVVNEILKKLLSA",
    "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLQQKIKAYLKLGKLGVVSLLDLAAVAGAFLAYKHGISLLPIIPMFIGGTLASMGAMIINSGIEIDRDKVMSRTSKRPTVVGYVNRKEAIIVGSLLAILGTALGFIDNILTAFFIALGVVIYIFVYTILLKPRTWLNIVIGGFAGSAAAWAGYTSLTNSLTLEGFLLGFLIFMWTPGHFWSLALKYREDYVNAHYPMLPAVVGITTSARAIAISNALMIPIVLLLGYYINLIALIAFSILSLFLMFLSYRLILNPTKEEAIKSFIFSNIYLMLILLIMIIVKLI",
    "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASLLKSLTLFKRTRDQPPLASGSGGAIRGIKHVIIVLIPGDSSIVTRSRLLDRLVRLVGDPKINGPKLTGILISILSLFVESPGQLIQRIIDDPDVSIKLVEVIPSINSACGLTFASRGASLDSEADEFFKIVDEGSKAQGQLGWLENKDIVDIEVDNAEQFNILLASILAQIWILLAKAVTAPDTAADSEMRRWIKYTQQRRVVGEFRMNKIWLDIVRNRIAEDLSLRRFMVALILDIKRSPGNKPRIAEMICDIDNYIVEAGLASFILTIKFGIETMYPALGLHEFSGELTTIESLMMLYQQMGETAPYMVILENSVQNKFSAGSYPLLWSYAMGVGVELENSMGGLNFGRSYFDPAYFRLGQEMVRRSAGKVSSALAAELGITKEEAQLVSEIASKTTEDRTIRATGPKQSQITFLHSERSEVANQQPPTINKRSENQGGDKYPIHFSDERLPGYTPDVNSSEWSESRYDTQIIQDDGNDDDRKSMEAIAKMRMLTKMLSQPGTSEDNSPVYSDKELLN",
    "output": "Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPRSLKKGPFLDLHLLKKVEKAVESGDKKPIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSDEMIGHKLGEFAPTRTYRGHAADKKAKK",
    "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLRTMLKSKIHRATVTQAYLHYVGSVTIDADLMGAADLLEGEQVTIVDINNGARLVTYAIAGERGTGVIGINGAAAHLVHPGDLVILISYGTMEDAEAHAYQPRIVFVDADNKPIDLGHDPGSVPLDISVAAELFDPRIGAR",
    "output": "Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSGALLVAGTSSDAGKSVVVAGLCRLLARRGVRVAPFKAQNMSNNSAVTVEGGEIGRAQAIQARAAGLEPSVRFNPILLKPGSDRTSQLVIKGQVAESVTATSYVQHRDRLAALVLNELTCLRDEFDAVICEGAGSPAEINLRATDLANMGLARAADLAVILVGDIDRGGLLAHLFGTVAVLDPQDQALIAGFVVNKFRGDPALLQPGLRRLHDITGRPTYGVLPYADRLWLDAEDSLSVLAHRVVGAPDPPLGDDWLRVAAVRLPRISNSTDVEALACEPGVLVRWVSEPSDVADADLVVIPGSKATVADLSWLRERGLAAAITAHAAAGRPVLGICGGFQMLCRRIDDRVESGAGEVAGLGLLDADIAFHPAKTLRRWQRPLAGYEIHHGRVSRCAEHSWFDSDAEPQGLVRGAVFGTHWHGLLDNDDFRRAWLVRVADAAGRRFVPGDTDVAARRDAQLDLAADLLAAHLDVDAVLGLLDGPPPRPRLATRLCR",
    "output": "Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRNILPFLTRIPVKGDFEKARNELWAFPLVALVSSALPTLILYLGLPLSNLLAVLALYWTIGLLHLDGLADWADGIMAKGDRERKIEVMKDVNTGIAGLFAVVIVLLLQVYSLQLLPFYALFLAELNSKYAMLLALATKRPLGKGLGAYFMEGMNGRQLALGTLLYVLLGLSVVLFEPRALAGILGLLFGVHIIRISLKNFDGLNGDCLGATAEITRAGTLVVMALVWWYL",
    "output": "Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTDSNDPVVRGYLLQLIGEEGIEMIENMPEGEVTDEQIAEASGVMLNIVRRTLFIMNENNLAVCRRERDSSSGWLTYLWQLDLSDIESHLVKEKKRITKNLEIRYNFEVDSVFYTCPEGCVRFEFKEASKCEFMCPACGEDMMFEDNSVMVKKLRDRLDALEASS",
    "output": "Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEHFLLEVAAAPLRLIAAKNEKSRSELGRFLAKQVWTPQDRQCVLSTLAQLLLDKDCTVLVGRQLRPLLLDLLERNAEAIKAGGQINHDLHERLCVSMSKLIGNHPDVLPFALRYFKDTSPVFQRLFLESSDANPVRYGRRRMKLRDLMEAAFKFLQQEQSVFRELWDWSVCVPLLRSHDTLVRWYTANCLALVTCMNEEHKLSFLKKIFNSDELIHFRLRLLEEAQLQDLEKALVLANPEVSLWRKQKELQYLQGHLVSSDLSPRVTAVCGVVLPGQLPAPGELGGNRSSSREQELALRSYVLVESVCKSLQTLAMAVASQNAVLLEGPIGCGKTSLVEYLAAVTGRTKPPQLLKVQLGDQTDSKMLLGMYRCTDVPGEFVWQPGTLTQAATMGHWILLEDIDYAPLDVVSVLIPLLENGELLIPGRGDCLKVAPGFQFFATRRLLSCGGNWYRPLNSHATLLDKYWTKIHLDNLDKRELNEVLQSRYPSLLAVVDHLLDIYIQLTGEKHHSWSDSSVGCEQAPEEVSEARRENKRPTLEGRELSLRDLLNWCNRIAHSFDSSSLSASLNIFQEALDCFTAMLSEHTSKLKMAEVIGSKLNISRKKAEFFCQLYKPEIVINELDLQVGRVRLLRKQSEAVHLQREKFTFAATRPSSVLIEQLAVCVSKGEPVLLVGETGTGKTSTIQYLAHITGHRLRVVNMNQQSDTADLLGGYKPVDHKLIWLPLREAFEELFAQTFSKKQNFTFLGHIQTCYRQKRWHDLLRLMQHVHKSAVNKDGKDSETGLLIKEKWEAFGLRLNHAQQQMKMTENTLLFAFVEGTLAQAVKKGEWILLDEINLAAPEILECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPPGIRNRFTELYVEELESKEDLQVLIVDYLKGLSVNKNTVQGIINFYTALRKESGTKLVDGTGHRPHYSLRTLCRALRFAASNPCGNIQRSLYEGFCLGFLTQLDRASHPIVQKLICQHIVPGNVKSLLKQPIPEPKGGRLIQVEGYWIAVGDKEPTIDETYILTSSVKLNLRDIVRVVSAGTYPVLIQGETSVGKTSLIQWLAAATGNHCVRINNHEHTDIQEYIGCYTSDSSGKLVFKEGVLIDAMRKGYWIILDELNLAPTDVLEALNRLLDDNRELLVTETQEVVKAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVMLDLQSYRRSSSVFAGKQGFITLRDLFRWAERYRLAEPTEKEYDWLQHLANDGYMLLAGRVRKQEEIDVIQEVLEKHFKKKLCPQSLFSKENVLKLLGKLSTQISTLECNFGHIVWTEGMRRLAMLVGRALEFGEPVLLVGDTGCGKTTICQVFAALANQKLYSVSCHLHMETSDFLGGLRPVRQKPNDKEEIDTSRLFEWHDGPLVQAMKEDGFFLLDEISLADDSVLERLNSVLEVEKSLVLAEKGSPEDKDSEIELLTAGKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTSREDLIQIISHNLRPGLCLGRIDPKGSDIPEVMLDFIDWLTHQEFGRKCVVSIRDILSWVNFMNKMGEEAALKRPEIISTVTSFVHAACLVYIDGIGSGVTSSGFGTALLARKECLKFLIKRLAKIVRLTEYQKNELKIYDRMKAKEFTGIDNLWGIHPFFIPRGPVLHRNNIADYALSAGTTAMNAQRLLRATKLKKPILLEGSPGVGKTSLVGALAKASGNTLVRINLSEQTDITDLFGADLPVEGGKGGEFAWRDGPLLAALKAGHWVVLDELNLASQSVLEGLNACFDHRGEIYVPELGMSFQVQHEKTKIFGCQNPFRQGGGRKGLPRSFLNRFTQVFVDPLTVIDMEFIASTLFPAIEKNIVKKMVAFNNQIDHEVTVEKKWGQKGGPWEFNLRDLFRWCQLMLVDQSPGCYDPGQHVFLVYGERMRTEEDKKKVIAVFKDVFGSNSNPYMGTRLFRITPYDVQLGYSVLSRGSCVPHPSRHPLLLLHQSFQPLESIMKCVQMSWMVILVGPASVGKTSLVQLLAHLTGHTLKIMAMNSAMDTTELLGGFEQVDLIRPWRRLLEKVEGTVRALLRDSLLISADDAEVVLRAWSHFLLTYKPKCLGEGGKAITMEIVNKLEAVLLLMQRLNNKINSYCKAEFAKLVEEFRSFGVKLTQLASGHSHGTFEWVDSMLVQALKSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTISERGMIDGSTPTITPNPNFRLFLSMDPVHGDISRAMRNRGLEIYISGEGDASTPDNLDLKVLLHSLGLVGNSVCDILLALHTETRSTVVGSPTSSVSTLIQTAILIVQYLQRGLSLDRAFSEACWEVYVCSQHSPANRKLVQALLEKHVSSLRAHETWGDSILGMGLWPDSVPSALFATEDSHLSTVRRDGQILVYCLNRMSMKTSSWTRSQPFTLQDLEKIMQSPSPENLKFNAVEVNTYWIDEPDVLVMAVKLLIERATNQDWMLRVKWLYHLAKNIPQGLESIQIHLEASAASLRNFYSHSLSGAVSNVFKILQPNTTDEFVIPLDPRWNMQALDMIRNLMDFDPQTDQPDQLFALLESAANKTIIYLDREKRVFTEANLVSVGSKKLRESVLRMSFEFHQDPESYHTLPHEIVVNLAAFFELCDALVLLWVQSSQGMVSDASANEILGSLRWRDRFWTVADTVKVDAPGLALLALHWHWVLKHLVHQIPRLLMNYEDKYYKEVQTVSEHIQNCLGSQTGGFAGIKKLQKFLGRPFPFKDKLVVECFSQLKVLNKVLAIREQMSALGESGWQEDINRLQVVASQWTLKKSLLQAWGLILRANILEDVSLDELKNFVHAQCLELKAKGLSLGFLEKKHDEASSLSHPDLTSVIHLTRSVQLWPAMEYLAMLWRYKVTADFMAQACLRRCSKNQQPQINEEISHLISFCLYHTPVTPQELRDLWSLLHHQKVSPEEITSLWSELFNSMFMSFWSSTVTTNPEYWLMWNPLPGMQQREAPKSVLDSTLKGPGNLNRPIFSKCCFEVLTSSWRASPWDVSGLPILSSSHVTLGEWVERTQQLQDISSMLWTNMAISSVAEFRRTDSQLQGQVLFRHLAGLAELLPESRRQEYMQNCEQLLLGSSQAFQHVGQTLGDMAGQEVLPKELLCQLLTSLHHFVGEGESKRSLPEPAQRGSLWVSLGLLQIQTWLPQARFDPAVKREYKLNYVKEELHQLQCEWKTRNLSSQLQTGRDLEDEVVVSYSHPHVRLLRQRMDRLDNLTCHLLKKQAFRPQLPAYESLVQEIHHYVTSIAKAPAVQDLLTRLLQALHIDGPRSAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFYPDAVSPLQASILQLQHGMRLVASELHTSLHSSMVGADRLGTLATALLAFPSVGPTFPTYYAHADTLCSVKSEEVLRGLGKLILKRSGGKELEGKGQKACPTREQLLMNALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQERIAQEKAEQESGLYRYRSRNSRTALSEEEEEEREFRKQFPLHEKDFADILVQPTLEENKGTSDGQEEEAGTNPALLSQNSMQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELNDRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPNVPEARQCQPVLQGFSEAVSHLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEILLAKAQDWEENASRALSLRKHLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTKHWFSIYQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVFHCHVLLMPQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKWNDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLPRPTDGAASELSSIQNLNRALRETLLAQPAAGQATIPEWCQGAAPSGLEGELLRRLPKLRKRMRKMCLTFMKESPLPRLVEGLDQFTGEVISSVSELQSLKVEPSAEKEKQRSEAKHILMQKQRALSDLFKHLAKIGLSYRKGLAWARSKNPQEMLHLHPLDLQSALSIVSSTQEADSRLLTEISSSWDGCQKYFYRSLARHARLNAALATPAKEMGMGNVERCRGFSAHLMKMLVRQRRSLTTLSEQWIILRNLLSCVQEIHSRLMGPQAYPVAFPPQDGVQQWTERLQHLAMQCQILLEQLSWLLQCCPSVGPAPGHGNVQVLGQPPGPCLEGPELSKGQLCGVVLDLIPSNLSYPSPIPGSQLPSGCRMRKQDHLWQQSTTRLTEMLKTIKTVKADVDKIRQQSCETLFHSWKDFEVCSSALSCLSQVSVHLQGLESLFILPGMEVEQRDSQMALVESLEYVRGEISKAMADFTTWKTHLLTSDSQGGNQMLDEGFVEDFSEQMEIAIRAILCAIQNLEERKNEKAEENTDQASPQEDYAGFERLQSGHLTKLLEDDFWADVSTLHVQKIISAISELLERLKSYGEDGTAAKHLFFSQSCSLLVRLVPVLSSYSDLVLFFLTMSLATHRSTAKLLSVLAQVFTELAQKGFCLPKEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILEPTQAAKLKGDYRTGKRLNIRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLLEVGQIAVCSFGESVKLLHPFHEQFSDYSGSQILRLCKFQQKKTKIAQFLESVANMFAAAQQLSQNISSETAQLLLVVSDGRGLFLEGKERVLAAVQAARNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPYYIILRDVNALPETLSDALRQWFELVTASDHP",
    "output": "Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits . Functions at successive maturation steps to remove ribosomal factors at critical transition points, first driving the exit of early pre-60S particles from the nucleolus and then driving late pre-60S particles from the nucleus (By similarity). At an early stage in 60S maturation, mediates the dissociation of the PeBoW complex (PES1-BOP1-WDR12) from early pre-60S particles, rendering them competent for export from the nucleolus to the nucleoplasm (By similarity). Subsequently recruited to the nucleoplasmic particles through interaction with SUMO-conjugated PELP1 complex . This binding is only possible if the 5S RNP at the central protuberance has undergone the rotation to complete its maturation (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSWQQRVDDALTARRATDTLRRRYVVSQGAGRWLVANGRQYLNFSSNDYLGLSQHPQIIRAWQQAAIRFGVGSGGSGHISGYSVAHQALEEELAQWLGYPRALLFISGFAANQAVITALMKKNDRIVADRLSHASLLEAANLSPAQLRRFIHNDTQHLSRLLQSPCVGQQLVVTEGVYSMDGDSAPLAEIQHIARRHHAWLLVDDAHGIGVTGDEGRGTCWQRGVKPELLVVTFGKGFGVSGAAVLCSESVADYLLQFARHLVYSTSMPPAQAQALSASLAVIRSDEGRERREKLAALVQRFRAGVNASRFTLLNAHSAIQPLIVGDNSRALRLAEALRQQGCWATAIRPPTVPVGTARLRLTLTQAHEACDIDRLLEVLHGAGE",
    "output": "Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTATLIDGNALSKTLRAQAAERAAALAARGHRPGLAVILVGDNPASEVYVRNKIKACEDNGFFSLKDRYPATLSEPELLARIDELNRDPKIHGILVQLPLPAHIDSHKVIEAIAPEKDVDGFHVANAGALLTGKPLFRPCTPYGVMKMFEAYKIPLQGANAVVIGRSNIVGKPMALLLLEAGATVTICHSKTRELAAHTRAADIVVAAVGKRNVLTADMVKPGATVIDVGMNRNDEGKLCGDVDFAGVSQVAGHITPVPGGVGPMTITMLLVNTIEAAERAAAAA",
    "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRDLVDTTEMYLRTIYELEEEGIPPLRARIAERLDQSGPTVSQTVARMERDELLTVEKDRSLKLSAQGRALATAVMRKHRLAERLLTDVIGLPWEKVHDEACRWEHVMGDEVEVQLVKVLSEYATSPFGNPIPGLDELMEGIPDSERAELQQKIDNLQVVTSQRASDIEPPEPIQVKILSINEIIQVEHKLMAKFHALGMRPGSVVDLVATEDGLEFSNDNGAMVVPEELGHAVRVEKVN",
    "output": "Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAATKHSLADSEDRPTKKTKVDSEEKARLKAEKRERKEKKKSQESEPSAENSDADRAAEKERKKAKKAKKLEKKQKLAEAEASAEPAAEVSDEAPKKSKKEKKTTTTEASSNSEAPSSGSYIQTIALSNVPQAEIDEFLSKNEIHITDPKTENVTLRPVLEFHQLPATNLLEKKPSPFANYKAPTPIQSASWPFTLSGRDVIGVAETGSGKTMAFALPCVEAISALKHKHTKAVVVSPTRELAMQTYEQMASVAALNRMKCVCLYGGASKDDQRNLLNRGADIIVATPGRLKDFMSDGTVDLSHSAFAVLDEADRMLDKGFEEDIKMILSSCPPREKRQTLMFTATWPQSVQTLAATFMVSPVKIAIGSGGKETAGGAVELQANARISQSVEVLEPRGKEFRLLEVLKEHQQGSKKNDRILVFCLYKKEATRIENFLSRKGIRVGGIHGDLRQEQRTRSLEAFKSGQTPVLVATDVAARGLDIPEVKLVINVTFPLTIEDYVHRIGRTGRAGKTGQAITFFTVEDKSHSGSLVNILRGANQPVPEDLLKFGTTVKKKAHDMYGAFFKDVDMNAKSTKITFD",
    "output": "ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSSHHQILQIRSDPFVLSHCCRHTRLTSSLTLQSPLKQPFSCLPFRWRRSYRGGVRSSTTETHGSKKEALVSETATTSIELKRVYPFHEIEPKWQRYWEDNRIFRTPDDVDTSKPKFYVLDMFPYPSGAGLHVGHPLGYTATDILARLRRMQGYNVLHPMGWDAFGLPAEQYAIETGTHPKTTTLKNIDRFRLQLKSLGFSYDWDRELSTTEPDYYKWTQWIFLQLYKKGLAYQAEVPVNWCPALGTVLANEEVVDGVSERGGHPVIRKPMRQWMLKITAYADRLLEDLDELEWPESIKEMQRNWIGRSEGAELNFSILDGEGRETDKEITVYTTRPDTLFGATYMVVAPEHQLLSYFVTAEQKQQVEEYKDFASRKSDLERTELQKDKTGVFTGCYAKNPANGDAIPIWVADYVLASYGTGAIMAVPAHDTRDNEFALKYNIPIKWVVRNEANSSDDAKQVYPGLGIIENSSTLETGLDINQLSSKEAALKVIEWAERTGNGKKKVNYKLRDWLFARQRYWGEPIPILILDESGETIAISESELPLTLPELNDFTPTGTGEPPLSKAVSWVNTVDPSTGKPAKRETSTMPQWAGSCWYYLRFMDPKNPEALVDKEKEKYWSPVDVYVGGAEHAVLHLLYSRFWHKVLYDIGVVSTKEPFKCVINQGIILGEVQYTAWKDQEGNYVSADTEERLNEHQQVTIPEEKVIKSGDHFVLKEDPSIRLIPRVYKMSKSRGNVVNPDDVVLEYGADSLRLYEMFMGPFRDSKTWNTSGIEGVHRFLARTWRLVIGLPQSDGSFKDGTLVTDDEPTLEQLRTLHKCIAKVTEEIESTRFNTGISGMMEFVNAAYKWNNQPRGIIEPFVLLLSPYAPHMAEELWSRLGHPNSLAYESFPKANPDYLKNTTIVLPVQINGKTRGTIEVEEGCSEDDAFVLASQDDKLRKYLDGQSIKKRIYVPGKILNVILDRTNVKVTTK",
    "output": "Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPRRRVVAAREILPDPKFSSQTIAKFMNHVMQDGKKSIAESIVYGALERVQEKNKVDPVEFFETTLEKVRPMVEVKARRVGGATYQVPMEVRPSRRTALAMRWLVDAAAKRSEKTMALRLAGELLDAAEGKGAAIKKREDVHRMAEANKAFSHYRF",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSAIPQEILHEAVTAKKASIQPFAASEKVYLQGSRPDLRVPMRKISQSDTPTNTGREKNPPVYVYDTSGPYTDPTVSVDLRLGLPPLREPWIEERGDTELLKGPSSSYGLQRQRDPALASLRFEHIRAPRRAKGGANVTQMHYARQGIITPEMEFVAIRENQKLEALAETYKFQHPGEAFGAAIPQVITPEFVRDEVARGRAIIPSNINHPESEPMIIGRNFLVKINCNLGNSAVSSSIEEEVEKMLWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGIRLPFIPLTAKRTTGIVSRGGSIMAKWCLAHHKESFLYTHFEDICEIMKAYDVAFSLGDGLRPGSIADANDEAQFAELRTLGELTRIAWKHDVQVMIEGPGHVPMHMIKANMEEQLKHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKQDVRDGIIAYKIAAHAADLAKGHPGAQARDNALSKARFEFRWQDQFNLSLDPEKALEFHDETLPQEGAKQAHFCSMCGPHFCSMKITQDVRDYAREHGLDEAQALAKGMEEKSDEFVRSGAEVYQRT",
    "output": "Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRRFALTVALPKGRMFREAYEVLKRAGLDLPEVEGERTLLHGKEGGVALLELRNKDVPIYVDLGIAEIGVVGKDVLLDSGRDLFEPVDLGFGACRLSLIRRPGDTGPIRRVATKYPNFTARLLKERGWAADVVELSGNIELAAVTGLADAVVDVVQTGATLRAAGLVEVEVLAHSTARLVVNRQALKLKRAVLKPLIQRLRELSGS",
    "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIDKSAFIHPTAIVEDGAVIGANAHIGPFCIVGPQVEIGEGTVLKSHVVVNGQTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHVAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREGLVAIRNAYKLLYRSGKTLDEAKLEIAELAEKHPEVKAFTEFFERSTRGPIR",
    "output": "Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MACSTHLLSQSLYPLNRANPAAARGHLRFQASPSVRLGSGTSRRRALGLRVAASAEQGRRQVEVEYDLQAKFNKLADQIDQNAGITRLNLFSPCKINVFLRITGKRPDGFHDLASLFHVISLGDTIKFSLSPSKSKDRLSTNVAGVPVDESNLIIKALNLYRKKTGTDNFFWIHLDKKVPTGAGLGGGSSNAATALWAANQFSGCIASEKELQEWSGEIGSDIPFFFSQGAAYCTGRGEIVEDIRNPLPANLPMVLVKPPEACSTAEVYKRLRLEHTSQTDPLVLLKEITENGISQDACVNDLEPPAFEVLPSLKRLKKRIIAANRGDYDAVFMSGSGSTIVGIGSPDPPAFVYDDDDYKDTFVSEACFLTRNENEWYREPISSKITSEEDLPPEVASVSD",
    "output": "Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. Is essential for chloroplast development (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPLLDSFTVDHTRMNAPAVRIAKSMVTPKGDTITVFDLRFCVPNKEILSERGIHTLEHLFAGFMREHLNGDSVEIIDISPMGCRTGFYMSLIGAPTESIVADSWLAAMQDVLKVAVQSDIPELNEYQCGTFEMHSLEQAQEIARNIIASGINVNRNDDLSLSEEILKGL",
    "output": "Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPPVTPLLDTVSSPADTRGLSIAQLRQLADEVRAETIDAVSQTGGHLGAGLGVVELTVALHHVYETPKDILIWDVGHQAYPHKILTGRRDRIRTLRQGGGLSGFTKRAESDYDPFGAAHAATSISAALGFCAARDREGRDNKVVAVIGDGSMSAGMAYEAMNNAYETTKQLTVILNDNDMSIAPPVGGMSAYMARLVSGGGYQSLRNLGKAVSRAFPRPLQEAARKAEEYARGMVTGGTFFEELGFYYVGPIDGHDMDALVHVLQNARKIDDKPVLVHVVTQKGKGYAPAEKAADKYHGVVKFDVVTGAQAKSQAAAPSYTKVFAQELVKHAERDERVVAITAAMPSGTGLDLFGQRFPERTFDVGIAEQHAVTFAAGLAADGMKPFAAIYSTFLQRGYDQVVHDVAIQSLPVRFAIDRAGLVGADGPTHAGSFDVGFMGQLPGMVVMGPADEAELARAIATAVAIDDRPSAFRYPRGEGVGVEIPALADPLEIGRGRIVREGTAVAILSFGTRLGESLKAADMLAARGLSATVADARFAKPLDVDLLLRLAREHEALITVEEGAVGGFGGFVLHALAEHGALDRGLKIRTLTLPDIFQDQDKPEAMYAQAGLDAEGIVRAALAALGIDNASVKGRRA",
    "output": "Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSVSQVTDASFKQEVINNNLPVLVDFWAPWCGPCRMVSPVVDEIAEEYESSIKVVKINTDDNPTIAAEYGIRSIPTLMIFKAGERVDTVIGAVPKSTLASTLNKYIS",
    "output": "Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKRVVLTGTGSGVGKTTIATGIMKALSDEHKIQPFKVGPDYIDPSYHNCATGVSSRNLDSFFMSDGQIRQSFKNGMTSSHADYGIIEGVRGLYEGISPTNDIGSTSSIAKALNSPVILIINSRSLVRSAAAMTLGFKALDSRIDIEGVILNNVKSQKHYLKTKEAVEKLANTRVLGGIERDNSISMEQRHLGLIPAVEQERISGLVEKWGELIRENIDLDALMEIMDNSNPIINEYEPIWSPNKTKHKTRIAVPFDEAFNFYYKENLEALEYNNAKIEYFSPIHDEQLPSVDALYIGGGYPEIFKKELSKNTTMLESIKEFSQDNHPIYAECGGLMYLCKTIDSLPMVDVFPYHSMLTKRVQGLSYTIAHVQRDNPILKKNTTYHGHEFHYSKVEYTGSNSNDFAFSMRRGVGITGKYDGLLKNNTLASYIHTHTACLPDFGYNFTQSAYENK",
    "output": "Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGNNFWSTWSPSQRIFSLIWPATILYLIMKLLIEKMWGKNRGAVERFQTRREALFDDFKSRSAPASLVNNPRIVKGNETAEQIETTFNEILKLDLIALKSALQTDKYNAYTVLCAFVWRAIDVNSEINCITEVIREAFNTAEALDDNYAQTGEKGQLFGLPFSVKSNFYMENYDVTVGLAKLLEQPKTTTCPMVQFLSDQGAVPFCLTNVPQGLLSYVSSNPIYGTTKNPWDFSRTPGGSSGGEAALLAAGGAAFGIGSDLAGSLRIPAAFCGLVTLKPTQDRLCVTDTHGGLPGRGRLGLSFGFYTRSVKEQEFLLGLIVGRSEYLELCPMSSPAKLEKHIEKDQKLVIGWFVDDGFNPVVPSNRRAVEETVKSLQAKGHQVVELKLADVSEEFPPFAVADMLFRNVMPDNGAYMSEMYAGEQYDEHMKLFIRLVCLKQNFLVSFLLRYGVMPFAKLALSKRLACIGSAYNSDLAACRQNQENTDSYKLQWIRYWKSKKIDALICPSFITPAQPFEYPAQLSNGAFITGLFNMLDVPAGVVPVSPVNQKDVDQLIDGFSTEGDLLLKKQREAARGTTGLPNAVQVVTLPNCEEMCLRVMRLVEESAEGVQRLQWRVGASAAPIDVENTPAGVVSSLEHFERVNLLH",
    "output": "Converts monoacylglycerides to free fatty acids and glycerol . Hydrolyzes the endocannabinoid 2-arachidonoylglycerol (2-AG), and thereby regulates the degradation of endocannabinoid-related monoacylglycerides . Also hydrolyzes arachidonoyl ethanolamide (anandamide, or AEA), but with low efficiency . Plays a role in the regulation of longevity and resistance to oxidative stress ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNKIRFLDKYLVQKIAAGESIDRPCSILRELLDNSIDSGATKIEVFLEEGGIHKILIIDNGIGIGKEDLKICYLPHTTSKISSEEDLRKIETLGFRGEALSSIAICSNISITSSTTGNESYQIEVENGIEKCFKKQPAINGTIVNVTKIFHNFPARKRFLKQEPIETKMCLKVLEEKIITHPEINFEINLNQKLRKIYFKESLIDRVQNVYGNVIENNKFKVLKKEHENIKIELFLAPANFSKKSKRHIKTFVNRRPIDQKDLLEAITNGHSRIISPGNFPICYLFLEINPEYIDFNVHPQKKEVRFFNLPFLFKLISDNINNFFDKDINSYNEIVIKRQLTDDDNLIEMINQPKNLNKTNTYDIIQNKNLETEHTVNDLSKNIIQNDIGLRRYNSIIQNRPSFKENITNIFSDKFLEFEEPPNKNEKEEIKFNYIGQIFSEFLIVEKVNEIYFIDQHAVHEKIIYEKLRNSKKTVQKLLIPIEFTIVDKNIEEIIDSEIEEYKKMDIIISKIGPKKYQLESIPNICNQYENTLINFFQSRKSRTINSLESDLYANIACRKAVKTNDILSLEFSKFLIDEFFKLEIKHCPHGRKIYYKISKFELEKKVARA",
    "output": "This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLLRKGTVYVLVIRADLVNAMVAHARRDHPDEACGVLAGPEGSDRPERHIPMTNAERSPTFYRLDSGEQLKVWRAMEDADEVPVVIYHSHTATEAYPSRTDVKLATEPDAHYVLVSTRDPHRHELRSYRIVDGAVTEEPVNVVEQY",
    "output": "Protease that hydrolyzes the covalent CysO-cysteine adduct synthesized by CysM to release L-cysteine and regenerate CysO."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAPAAASGGSTLPSGFSVFVTFPDLLFIFEFIFGGLVWILIASSLVPMPLVQGWVMFVSVFCFLATTSLMVMYIIGTHGGETSWITLDAAYHCVAALFYLSASVLEALATITMFDGFTYRHYHENIAAVVFAYVATLLYVIHAVFSLIRWKSS",
    "output": "Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSTQFRKSNHNSHSSKKLNPALKSKIDTLTELFPDWTSDDLIDIVQEYDDLETIIDKITSGAVTRWDEVKKPAKKEKYEKKEQQHSYVPQQHLPNPEDDITYKSSNNSNSFTSTKHNSSNNYTQARNKKKVQTPRAHTTGKHVNLDKGKHVPSKPVSNTTSWAAAVSVDTKHDVPQDSNDNNNEELEAQGQQAQENQEKEQEEQQQQEGHNNKEEHKQIEQPSLSSKKTTSKTSAPQPKKMSWAAIATPKPKAVKKTESPLENVAELKKEISDIKKDDQKSEASEEKVNEQETSAQEQEEETAEPSEENEDRVPEVDGEEVQEEAEEKEQVKEEEQTAEELEQEQDNVAAPEEEVTVVEEKVEISAVISEPPEDQANTVPQPQQQQQQQQQQPQQPQQQQQQPQQQQQPQQPQQQLQQQQQQQQQPVQAQAQAQEEQLSQNYYTQQQQQQFAQQQHQFQQQYLSQQQQYAQQQQQHPQPQSQQPQSQQSPQSQKQGNNVAAQQYYMYQNQFPGYSYPGMFDSQGYAYGQQYQQLAQNNAQTSGNANQYNFQQGYGQAGANTAAANLTSAAAAAAASPATAHAQPQQQQPYGGSFMPYYAHFYQQSFPYGQPQYGVAGQYPYQLPKNNYNYYQTQNGQEQQSPNQGVAQHSEDSQQKQSQQQQQQQPQGQPQPEVQMQNGQSVNPQQQMQFQQYYQFQQQQQQAAAAAAAAAQQGVPYGYNGYDYNSKNSRGFY",
    "output": "Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled repair (TCR) factor RAD26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation. Binds DNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARKPASSQDFETTLAKLENIVAHLENGDLPLEEALKEFEQGVQLAKLGQERLQQAEQRIQILLQKTEDAPLNDYKGNA",
    "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQKLQLCVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS",
    "output": "Acts specifically as a negative regulator of skeletal muscle growth."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTDVSRVLKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYKMGIVDRIIPEHGYFSSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY",
    "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLFATLEHILTHISFSTISIVITIHLITLLVRELRGLRDSSEKGMIATFFSITGFLVSRWVSSGHFPLSNLYESLIFLSWTLYILHTIPKIQNSKNDLSTITTPSTILTQGFATSGLLTEMHQSTILVPALQSQWLMMHVSMMLLSYATLLCGSLLSAALLIIRFRNSFDFFSLKKNVFLKTFFFSEIEYLYAKRSALKNTSFPVFPNYYKYQLTERLDSWSYRVISLGFTLLTVGILCGAVWANEAWGSYWNWDPKETWAFITWTIFAIYLHSRTNPNWKGTNSALVASIGFLIIWICYFGINLLGIGLHSYGSFTLPSK",
    "output": "Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYKKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFTYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTANILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEAPAAPQVTAEDASASLAELLNAGLGGSDNE",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MCPYRLDPEGADTHGETARLREQGPIARVELQDGVLAWSVHDYAVAKQIMADERFSKNPRKNWPAYINGEISNGWPLITWVAMDTMATQDGADHARLRKLLLKAFTERRVESMRPHIEKTVKELLDNMAAKADDEIVDIKEMFHAELPTRLMCDLFGVPEERRAEVLAGGHKNIDTRISSEAAEANLGQWQEAISDLVEYKRHHPGDDLTSALIEARDEGSRLSDSELIGTLHLLLGAGSETLVNALAHSSLALLVDADLRKKVTSGEIPWVNVWEETLRVESPVAHLPFRYATEDFEIGGVKISKGDPLLVDFAGIGRDPAVHSDAPDEFDALRPDKTHLSFGHGVHYCLGARLAKHAWMIGIPALFERFPDMELAVRRDELKGQGSFVVNGHASLPVHLKGRAAALAR",
    "output": "Involved in the biosynthesis of the naphthoic acid (NA) moiety in the chromophore of the enedyine antitumor antibiotic neocarzinostatin (NCS). Catalyzes the hydroxylation at C-7 position of 2-hydroxy-5-methyl-1-naphthoate to yield 2,7-dihydroxy-5-methyl-1-naphthoate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKKPRQIAFYGKGGIGKSTTSQNTLAQLATTFGQKIMIVGCDPKADSTRLILNTKAQQTVLHLAAELGSVEDLELEDVVATGFGGILCVESGGPEPGVGCAGRGIITSINFLEEQGAYDGMDFISYDVLGDVVCGGFAMPIRENKAQEIYIVCSGEMMAMYAANNIARGILKYAQSGSVRLGGLICNSRKTDREDELITELARRLNTQMIHFVPRDNVVQHAELRRMTVTQYNPEHPQANEYKQLADKILHNEKLTIPTPIEMDELEQLLIDFGVVEDEETAIKKLEAAGH",
    "output": "The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPSSQAHSAVDTPIENHFPGSLFMVVAPSGAGKSTLVNALLAQDPSIRLSVSATTRKPRPGEQHGREYNFMTVDEFKACRDRGEFLEWAEVHGNYYATSRVWIEEQMRAGTDVLLEIDWQGAQQVHRRFANAVEIFILPPSLTALEDRLKKRGQDEPNVIVRRLLAAGSEMAHAPEADYVIINEVFEAALAELRTVVQAARLRYMAQKARHAELFVELGIH",
    "output": "Essential for recycling GMP and indirectly, cGMP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSVQRPIRVLVVDDSPTMANMLTALLTEEPRIEVVGRAGDGNRAVQLARLLRPDVITMDLLLPGLDGPGAIAAIMSQSPARILVVSAVAEQRGVDLGFQAMSAGALELIGKPNVTNAEELRRWGKELAHSVCLMAEVPVISRRPRAATAPPPPTGARVDIFGVVASTGGPPALADVLSKLPRSLPVPLLIAQHITVGFTQGMVRWLSQVTPLPVSIAKDGERLEPGRVYFPLDGHDLLVDAAGLARLQPSQGGPCPSGDVMLTSLAAAFGRRSGGVVLTGMGEDGARGLLAIRRAGGVTFSQDEASSVVFGMPRAALDVKATDQGVPLASMPELILQSCTFAPFRGGRPEGGPTR",
    "output": "Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAAKDVKFGNEARIKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPSITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATLLAQSIVNEGLKAVAAGMNPMDLKRGIDKAVISAVEELKNLSVTCSDSKAITQVGTISANADEKVGSLIAEAMEKVGNDGVITVEEGTGLQDELEVVKGMQFDRGYLSPYFINKSETGIVELENPYILMADKKISNIREMLPILESVAKSGKPLLIISEDLEGEALATLVVNSMRGIVKVAAVKAPGFGDCRKAMLQDISILTNGTVISEELAMELEKSTLEDLGQAKRVVISKDTTTIIGGVGEKHAIQARINQIRQEIQDASSDYDKEKLNERLAKLAGGVAVLKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALVRVAGKLSNLRGQNEDQNVGIRVALRAMEAPLRQIVSNSGEEPSAVTNNVKDGKGNYGYNAATDEYGDMIDFGILDPTKVTRSALQYAGSVAGLMITTECMVTDLPKEDKSSDLGSAPAGGMGGMGGMM",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPGSEDLRKGKDQMHSHRKRTMFTKKQLEDLNILFNENPYPNPSLQKEMASKIDIHPTVLQVWFKNHRAKLKKAKCKHIHQKQETPQPPIPEGGVSTSVGLRNADTLPRLPNAAHPIGLVYTGHRVPSFQLILYPNLKVPANDFIGHRIVHFGCCRDPNIYCLYPILESQVCAPSFHSGSPACSSNQSRER",
    "output": "Transcription factor that acts as repressor."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "AVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQTFTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLITESVFARYISSLKDQRVAASKVLSGPQAQSAGDKAEFIEKVRRALYLGKIVSYAQGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPYFKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRI",
    "output": "Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKRLKKIDLNQKYDHKTVSEGVVDFWLTTDYANQDSDFCDPNAKPFSIIMPPPNLTGILHIGHAWNLSIQDLIVRYQKLVMGKINWIPGTDHAGIATQTKFESIQRTKEINYKKDDRTTHFNNIYQWSQESSQTIKNQAKSLGLALNWKKEKFTLSQESNKYVLDVFVKLYQQGYIVKKYTLVNWDTKLNTAISNIEVINKETTQKLHYIKYYLKDSNDYLVIATTRPETIYADVAVFVNPNDQRYLKYHNQMVINPLNNKLIPILVDEYIDMEFGSAVMKCTPGHDHNDYALSKKYQLEELSCINFDGTLNELALEFSGLDLYEARELIVKKLISEDKYVKFEEITSNVGYSDRSNVIVQPLLSKQWFLITTKFVDEIKKLVNNEDQIKIYPKRFLDTINNWLDHNQDWCISRQLVWGHQIPAWYHKDHPDEVIVSINSPGDDYYRDSDVLDTWFSSALWPLICFDDGLDQKEFNANFPNSLLVTAYDIVFFWVLRMIFMSWLLKKSIPFHDLLLHGLILDEHNRKMSKSLNNGVDPIQIIDQYGADALRLFLTSNTSPGEDVSYNVEKINAAASFLNKLWNLARYLKLIDQSKLTDQPLDSLDHWIIHRFNEVNAGIQDKLKEYRFALSNKQLSDFIWDDFANVYIELNKKAQWSKAKFELANDIFRKFLIMLHPSVPFITEQIYNTFEFSDSKPSIILEKWPGLIKIENALDHFDQIFNLIIKIRNFKQSFDLKNKDTLDLLYKNEVSYIKDLTKYLKTENVNLIKISDQKLNDLFLIATEDNEFYVVYTQDKTKIVDKLVVEIAKLEKEVERSSNIVNNKNFKKKAPKEKYEAELKKLSNYQEELKLKQDKLNSLK",
    "output": "Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTHPLVPPITDLAIPVAEQLGLEVVGIVFHTNQRPPVLRVDIRNPQQDTGLDDCERMSRALEAALDATEIIPDAYVLEVSSPGISRQLVTDREFISFKGFPVIVSTSPPHEGQQEWIGQLIRRDETKVYINQKGRVIEIPRSLITRVLLHDGE",
    "output": "Required for maturation of 30S ribosomal subunits."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTDKKLVKELAIEFGGSEKNVGAIEVQIAILTHDIERLKIHFETNKKDKHSKRGFIAKINKRKKLLAYLKDVNFESYQTTIQKLKIRK",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPELPEVETSRRGIEPHLVGATILHAHIRNGRLRWPVSDEIYRLSDTPVLSVQRRAKYLLLELPDGWIIIHLGMSGSLRILSEALPAEKHDHVDLVMSNGKILRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSTEECDLLARVIKAVLLRSIEQGGTTLKDFLQGDGKPGYFAQELQVYGRKGEPCRVCGTPIAATKHAQRATFYCRHCQK",
    "output": "Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHRGIPKSSKTQTHTQQDRPPQPSTELEETRTSRARHSTTSAQRSTHYDPRTSDRPVSYTMNRTRSRKQTSHRLKNIPVHGNHEATIQHIPESVSKGARSQIERRQPNAINSGSHCTWLVLWCLGMASLFLCSKAQIHWDNLSTIGIIGTDNVHYKIMTRPSHQYLVIKLIPNASLIENCTKAELGEYEKLLNSVLEPINQALTLMTKNVKPLQSLGSGRRQRRFAGVVLAGVALGVATAAQITAGIALHQSNLNAQAIQSLRTSLEQSNKAIEEIREATQETVIAVQGVQDYVNNELVPAMQHMSCELVGQRLGLRLLRYYTELLSIFGPSLRDPISAEISIQALIYALGGEIHKILEKLGYSGSDMIAILESRGIKTKITHVDLPGKFIILSISYPTLSEVKGVIVHRLEAVSYNIGSQEWYTTVPRYIATNGYLISNFDESSCVFVSESAICSQNSLYPMSPLLQQCIRGDTSSCARTLVSGTMGNKFILSKGNIVANCASILCKCYSTSTIINQSPDKLLTFIASDTCPLVEIDGATIQVGGRQYPDMVYEGKVALGPAISLDRLDVGTNLGNALKKLDDAKVLIDSSNQILETVRRSSFNFGSLLSVPILSCTALALLLLIYCCKRRYQQTLKQHTKVDPAFKPDLTGTSKSYVRSL",
    "output": "Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADKKSSPKKENPQDKTYAIVEASGKQFWLQPNRYYDFDRCQAEVDDVLTLENVLLLNDGKDLKLGKPYVKDAKVEIKVLEHRRGPKIIVYKMRPKKKTRRKNGHRQELTRVLVQSISIGSNTKKSKAVKTTASKVESD",
    "output": "This protein binds to 23S rRNA in the presence of protein L20."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEKMLLKSTTRHVRIFTAEVVNNDLKYHPNKLTLDLDPDNEFIWNEESLKKVNQKFTELVEERAGKSLDDYELRKIGSEVEGLIKYLLQNSLLSYNPECRVMNYSMGLPKTKEVL",
    "output": "NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDFLHLGSFVFSSRLILGTGKFSNADLMIEAIKASGAQLVTVALRRFNREQIADDLFGPLSALQGITLMPNTSGASTAREAIHAAHIARELSGSPFIKVEIHPNPQHLMPDALETWEASRILAKEGFLVMPYIPADPVLAKRLEEVGCASVMPLGSAIGSGQGLANAGMIELIIRESGIPVIVDAGLRAPSEAAAAMEMGCGAVLVNSAVAVAGNPPEMANAFAEAVRAGRRAFKAELMPKSSFALSTSPLTTFLGKKS",
    "output": "Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLNKRVIPCLDVNNGRVVKGTSFVNLRDAGDPVELAARYYREGADELVFLDISATTEERKTMAEVVEKVSKEVFIPLCVGGGLRSIADMTTLLRAGADKVSVNSAAVSDPDLISRGAEKFGRQCIVVAIDAKREGNSWQVYTHSGKKPTGLDAVEWAMKAEQLGAGEILLTSIDADGKNTGYDNELNREVGSRLNIPVIASGGAGSPEDLYNALDKGQADAVLAASIFHYGRYSIAEVKKYLKSKGLPVRLEN",
    "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDIERVEQVRAVERLAHRRGLALMPRAGLAAADFVAARLPAGAQVLALAGPGNNGGDALVAATLLQARGYRVAVVMPAGPARLPDDARRAWQDWCAAGGQASADLPAHAPALVIDGLFGIGLARPLDGAWQGLIDQVNAWRVPVLALDVPSGLSAASGQPLGDPPGRPVRATWTLSFIGVPAALRAPGAAAWCGEQYLSLLGLTPAFLAEAVGPCGQATATAARRSGP",
    "output": "Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDSITSAASVVAAGLAVGLGAIGPGLGQGNAAQGAVEGIARQPEAEGKIRGTLLLSFAFMESLTIYGLVVALVLLFANPFS",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKNPKKKSGGFRIVNMLKRGVARVSPFGGLKRLPAGLLLGHGPIRMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKKDLAAMLRIINARKEKKRRGADTSVGIVGLLLTTAMAAEVTRRGSAYYMYLDRNDAGEAISFPTTLGMNKCYIQIMDLGHMCDATMSYECPMLDEGVEPDDVDCWCNTTSTWVVYGTCHHKKGEARRSRRAVTLPSHSTRKLQTRSQTWLESREYTKHLIRVENWIFRNPGFALAAAAIAWLLGSSTSQKVIYLVMILLIAPAYSIRCIGVSNRDFVEGMSGGTWVDVVLEHGGCVTVMAQDKPTVDIELVTTTVSNMAEVRSYCYEASISDMASDSRCPTQGEAYLDKQSDTQYVCKRTLVDRGWGNGCGLFGKGSLVTCAKFACSKKMTGKSIQPENLEYRIMLSVHGSQHSGMIVNDTGHETDENRAKVEITPNSPRAEATLGGFGSLGLDCEPRTGLDFSDLYYLTMNNKHWLVHKEWFHDIPLPWHAGADTGTPHWNNKEALVEFKDAHAKRQTVVVLGSQEGAVHTALAGALEAEMDGAKGRLSSGHLKCRLKMDKLRLKGVSYSLCTAAFTFTKIPAETLHGTVTVEVQYAGTDGPCKVPAQMAVDMQTLTPVGRLITANPVITESTENSKMMLELDPPFGDSYIVIGVGEKKITHHWHRSGSTIGKAFEATVRGAKRMAVLGDTAWDFGSVGGALNSLGKGIHQIFGAAFKSLFGGMSWFSQILIGTLLMWLGLNTKNGSISLMCLALGGVLIFLSTAVSADVGCSVDFSKKETRCGTGVFVYNDVEAWRDRYKYHPDSPRRLAAAVKQAWEDGICGISSVSRMENIMWRSVEGELNAILEENGVQLTVVVGSVKNPMWRGPQRLPVPVNELPHGWKAWGKSYFVRAAKTNNSFVVDGDTLKECPLKHRAWNSFLVEDHGFGVFHTSVWLKVREDYSLECDPAVIGTAVKGKEAVHSDLGYWIESEKNDTWRLKRAHLIEMKTCEWPKSHTLWTDGIEESDLIIPKSLAGPLSHHNTREGYRTQMKGPWHSEELEIRFEECPGTKVHVEETCGTRGPSLRSTTASGRVIEEWCCRECTMPPLSFRAKDGCWYGMEIRPRKEPESNLVRSMVTAGSTDHMDHFSLGVLVILLMVQEGLKKRMTTKIIISTSMAVLVAMILGGFSMSDLAKLAILMGATFAEMNTGGDVAHLALIAAFKVRPALLVSFIFRANWTPRESMLLALASCLLQTAISALEGDLMVLINGFALAWLAIRAMVVPRTDNITLAILAALTPLARGTLLVAWRAGLATCGGFMLLSLKGKGSVKKNLPFVMALGLTAVRLVDPINVVGLLLLTRSGKRSWPPSEVLTAVGLICALAGGFAKADIEMAGPMAAVGLLIVSYVVSGKSVDMYIERAGDITWEKDAEVTGNSPRLDVALDESGDFSLVEDDGPPMREIILKVVLMTICGMNPIAIPFAAGAWYVYVKTGKRSGALWDVPAPKEVKKGETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMWHVTKGSALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGHSEVQLLAVPPGERARNIQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAITQGRREEETPVECFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAPTRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLYIMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEVPERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKTKHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQRRGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADKVAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIMEDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKRGAAFGVMEALGTLPGHMTERFQEAIDNLAVLMRAETGSRPYKAAAAQLPETLETIMLLGLLGTVSLGIFFVLMRNKGIGKMGFGMVTLGASAWLMWLSEIEPARIACVLIVVFLLLVVLIPEPEKQRSPQDNQMAIIIMVAVGLLGLITANELGWLERTKSDLSHLMGRREEGATIGFSMDIDLRPASAWAIYAALTTFITPAVQHAVTTSYNNYSLMAMATQAGVLFGMGKGMPFYAWDFGVPLLMIGCYSQLTPLTLIVAIILLVAHYMYLIPGLQAAAARAAQKRTAAGIMKNPVVDGIVVTDIDTMTIDPQVEKKMGQVLLIAVAVSSAILSRTAWGWGEAGALITAATSTLWEGSPNKYWNSSTATSLCNIFRGSYLAGASLIYTVTRNAGLVKRRGGGTGETLGEKWKARLNQMSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGKVIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPMLVQSYGWNIVRLKSGVDVFHMAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMMETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRPVKYEEDVNLGSGTRAVVSCAEAPNMKIIGNRIERIRSEHAETWFFDENHPYRTWAYHGSYEAPTQGSASSLINGVVRLLSKPWDVVTGVTGIAMTDTTPYGQQRVFKEKVDTRVPDPQEGTRQVMSMVSSWLWKELGKHKRPRVCTKEEFINKVRSNAALGAIFEEEKEWKTAVEAVNDPRFWALVDKEREHHLRGECQSCVYNMMGKREKKQGEFGKAKGSRAIWYMWLGARFLEFEALGFLNEDHWMGRENSGGGVEGLGLQRLGYVLEEMSRIPGGRMYADDTAGWDTRISRFDLENEALITNQMEKGHRALALAIIKYTYQNKVVKVLRPAEKGKTVMDIISRQDQRGSGQVVTYALNTFTNLVVQLIRNMEAEEVLEMQDLWLLRRSEKVTNWLQSNGWDRLKRMAVSGDDCVVKPIDDRFAHALRFLNDMGKVRKDTQEWKPSTGWDNWEEVPFCSHHFNKLHLKDGRSIVVPCRHQDELIGRARVSPGAGWSIRETACLAKSYAQMWQLLYFHRRDLRLMANAICSSVPVDWVPTGRTTWSIHGKGEWMTTEDMLVVWNRVWIEENDHMEDKTPVTKWTDIPYLGKREDLWCGSLIGHRPRTTWAENIKNTVNMVRRIIGDEEKYMDYLSTQVRYLGEEGSTPGVL",
    "output": "[Capsid protein C]: Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of the mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIENQSDNIDNKENDLSDQDNALENVSSAQELTTENNELSSQKTEEINTEELKNSISNNDARLEQLEKEHETLKNQYVRISADFDNFRKRQSRDQDDLKIQLVSKTLTAILPIVDNFERARQQLKPESEEAQSLHRSYQGLYKQLVEVLKQQGVSPMRVVGQQFDPSLHEAVLREPSEKFEEDFIIEELQRGYHLEGKVLRHALVKVSMGPGKQNSQEEVEKDKVEGDIDSEENTSEDV",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQKAGLLLRGWTRAWKSVRMASSGLTRQNPLANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTGVVCHVGKAEDREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMMIKAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAPGLIKTHFSSVLWKEKAREEMIKETMQIRRLGKPEDCVGIVSFLCSEDASYINGETVVVGGGTPSRL",
    "output": "NADPH-dependent oxidoreductase which catalyzes the reduction of a variety of compounds bearing carbonyl groups including ketosteroids, alpha-dicarbonyl compounds, aldehydes, aromatic ketones and quinones. Reduces all-trans-retinal and 9-cis retinal. Reduces 3-ketosteroids and benzil into 3alpha-hydroxysteroids and S-benzoin, respectively, in contrast to the stereoselectivity of primates DHRS4s which produce 3beta-hydroxysteroids and R-benzoin. In the reverse reaction, catalyzes the NADP-dependent oxidation of 3alpha-hydroxysteroids and alcohol, but with much lower efficiency. Involved in the metabolism of 3alpha-hydroxysteroids, retinoid, isatin and xenobiotic carbonyl compounds."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIPYATIEEASIALSRNLTWLETLWFDYSATKSDYYLYCHNILFLFLIFSLVPLPLVFIESSQSTSDLFNRYKIQPKVKNSFSSMFKCYKDVMKMFILVVGPLQLVSYPSIQMIEIRSGLPLPSCMEIVAQLVVYFLVEDYTNYWVHRFFHCKWGYEKFHHIHHEYTAPIGYAAPYAHWAEVLLLGIPTFLGPAIAPGHMITFWLWIALRQIEAIETHSGYDFPWSLTKYIPFYGGAEYHDYHHYVGGQSQSNFASVFTYCDYIYGTDKGYRFQKKLLQQMKEKSKKSNKLVNGGEKFD",
    "output": "Non-heme iron oxygenase involved in sterols biosynthesis by catalyzing the removal of the first methyl group at the C-4 position (By similarity). 4,4-dimethyl-9-beta,19-cyclopropylsterols such as 24-methylenecycloartanol are the preferred substrates (By similarity). Acts as a rate-limiting enzyme in the sterol pathway via interaction with ACBP1; sterols serve as lipid modulators for gene expression of homeodomain-leucine zipper IV transcription factors . Together with SMO1-1, involved in the maintenance of sterol composition to balance auxin and cytokinin activities during embryogenesis ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDLPEPIRRRLGDFSRTVFVDQSRTQPSFEEHANFLDQNKDVVSSLPLQMSLYFNMWFFPFWWISEVVMLDLKYSALADYYKFILITILIVMTLIEAIRLYLGNAGNLQEKVPELAGFWLLTFLLQFPLILFQLFNEAVLVQPLERGVHIILALFIFAEVLFGFVALRTMVRHTESRFHLRQFHGIQELRT",
    "output": "Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSWLSKLMPSGIRTENTPAKKRSVPEGLWEKCSNCGSALYGPELEENLEVCPKCDHHMAIRARARLAALFDLDSPTTEIAAQLGPVDVLKFKDQKKYGERIKASQKSSGEYDALIAMRGMLKGNPLVAAAFDFAFMGGSMGSVVGERFARAAEVALEVGCPFVCFSASGGARMQEGLFSLMQMAKTSAALGRLREAGLPYISVLTHPTTGGVSASFAMLGDINIAEPHALIGFAGPRVIEQTVRETLPEGFQRSEFLLDHGAIDQICDRRDMRDRIAELTTMMMRQPHPQDADAA",
    "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDRTEQKSIIEGLLFVSGDEGIYPEQIAKVLEIEGNEVIDILEEMQKECEGAHRGLQIVQYAKVYRFATKKEHASYYQKLIEIPTAASLSQAALETLAIVAYRQPITRTEMEEIRGVKTDKALQTLVSHLLIKEMGRAEGPGRPILYGTTKEFLDTFGLKTLDDLPPLSEENEQMNEADLFFGSLQEISK",
    "output": "Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKVLAINAGSSSLKFQLFEMPAETVLTKGVVERIGFDDAIFTIVVNGEKHQEVTAIPDHAAAVKMLLDKLIRYGIIRSFDEIDGIGHRVVHGGEKFSDSVLITEDVIKQIEEVSELAPLHNPANLVGIRAFQEVLPDVPAVAVFDTAFHQTMPEQSFLYSLPYEYYTKFGIRKYGFHGTSHKYVTQRAAELLGRPIEQLRLISCHLGNGASIAAVEGGKSIDTSMGFTPLAGVAMGTRSGNIDPALIPYIMEKTGMTADEVIEVLNKKSGMLGLSGISSDLRDLEKAAAEGNERAELALEVFANRIHKYIGSYAARMCGVDAIIFTAGIGENSEVVRAKVLRGLEFMGVYWDPILNKVRGKEAFISYPHSPVKVLVIPTNEELMIARDVMRLANL",
    "output": "Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFEYVTGYVEYVGPEYIVLDHNGIGYQIFTPNPYVFQRSKQEIRVYTYHYVREDIMALYGFKTREERLLFTKLLGVSGIGPKGALAILASGQTGQVVQAIENEDERFLVKFPGVGKKTARQMILDLKGKLADVVPDVFVDLFSDEERFDEKKGSSTELDEALEALRALGYAEREINRVLPELLKESLTTDQYIKKALSLLLNGKR",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHPVLRQMRPQPRATTASAAVALSGSGEQEEPQCPTLELEEGEGIARLGAHSPERHPRVQLARDSRVAFVPRQNMFRDNSGEEAEEMRDCRFRAGRELRRGFNRERLLREEDFEPDEHSGISSARAHVSAANLVTAYEQTVTEERNFQKSFNNHVRTLIAREEVAIGLMHLWDFVEAYVHNPASKPLTAQLFLIVQHSRDNETFRDAMLNIAEPQGRWLLDLINILQSIVVQERSLSLADKVAAINYSMLSLGKFYARKIYKSPYVPIDKEVKIDSFYMRMALKVLTLSDDLGVYRNDRIHKAVSASRRRELSDKELMHSLQRALTGAGTEDESFFDMGADLRWQPSARALEAAGVASADVTGDDDDEDQYED",
    "output": "Involved in viral genome packaging through its interaction with packaging proteins 1 and 2. After proteolytic cleavage by adenovirus protease, L1 52/55k protein is removed from the capsid during viral maturation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEQRIKFPRSEKVYLSGKLFPEIRVGMRKVEQVPSTTFEGEKKVITPNPHVYIYDTSGPFSDPDIEIDLKKGLPRLREEWILNRGDVEQLPEISSEYGRMRRDDGSLDHLRFEHIALPYRAKAGRHITQMAYAKQGIVTPEMEYVAIRENMNCEELGIETHITPEFVRQEIAEGRAVLPANINHPEAEPMIIGRNFLVKINTNIGNSATTSSIDEEVEKAMWSCKWGGDTLMDLSTGENIHETREWIIRNCPVPVGTVPIYQALEKVNGKVEDLTWELYRDTLIEQCEQGVDYFTIHAGIRRHNVHLAEKRLCGIVSRGGSIMSKWCLVHDRESFLYEHFDDICDILAQYDVAVSLGDGLRPGSTHDANDEAQFAELDTMGELVVRAWEKNVQAFIEGPGHVPMHKIRENMERQIEKCHNAPFYTLGPLVTDIAPGYDHITSAIGAAQIGWLGTAMLCYVTPKEHLALPDKEDVRVGVITYKIAAHAADLAKGHPGAQVRDNALSKARYEFRWKDQFDLSLDPERAFSYFHAGRHTDGEYCTMCGPNFCAMRLSRDLKKTQKQK",
    "output": "Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDKTLTRADLAESVYREVGLSRQESADLVQSVLAMVSDNLAAGQSVKLSSFGSFLLRDKRGRVGRNPKTGVEVPIDARRVLVFKPSQVLKERVDSALSKD",
    "output": "This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQYSTLAGQTDNSLVSNNFGFLRLPLNFMPYESHADWVITGVPYDMAVSGRSGARFGPEAIRRASVNLAWEHRRFPWTFDVRERLNIIDCGDLVFSFGDSRDFVEKMEAHAGKLLSSGKRCLSLGGDHFITLPLLRAHARYFGKLALIHFDAHTDTYDNGSEYDHGTMFYTAPKEGLIDPSRSVQIGIRTEHSKKLPFTVLSAPKVNEDSVEETVRKIKETVGNMPVYLTFDIDCLDPSFAPGTGTPVCGGLSSDRALKILRGLTDLDIVGMDVVEVAPSYDQSDITALAGATIALEMLYLQGAKKD",
    "output": "Catalyzes the formation of putrescine from agmatine."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSTVKQRTRTEGKPQYPLMQSIKDTLKLKTTKRTNSEKKVSTLNDKSGSPIKSNSERRNGITRKVNGSKRLSAQRVALFKYNNVQVFNYVRNGNNSRKSSMSSLNSSGTVVMCNEYDSEVTNLKPQMLIGKGVLELYQIKTPAALDRKEQTMNYISLGRGGQIVHPILPKLKITKLRNENFKYLITFSNPERYWQIEFLQINGQLHDELLKITDEFESIISSVCIFIDENITKLASLKSNKTPPNNVNTLDQIKEKVQTATENDDDEAEELDYLLEDPIEQEPTSSFEYDVPTDLTEVFQRTMGRINSNGSRRYSSVPQFSHRRSMIRRSMSLFPEHEGRFS",
    "output": "Required for peroxisome inheritance."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSPTAEIPKPVAVVGISAEFPSGTLSDANFDHQSFFDFLLSGKDAVERIPKDRFNIDGWQGSHLGQILPEDACFLKNVHLFDHFEFGISSKDALTMGAGTRKLVEHSFLALLDSGINCRSQNVAAFSSAVAFDLLSAADADEFEPRDGFGGGAAAVANRISYQLDLLGPSIPVDTACSSSLMALHLGVQSLRAGECEAAVIGGSQINHRFLDWIFYSQLSILSPGGKSIPFDSSADGFGRGEAVVVLVVKLLEDAIRDGDKIYATVLNTAVNSTGSAGPVKTPIAESQAAAMLTAYKGIGRSPSEADFIECHATGTSVGDPVEANWVGNHFKRDSELLIGSVKGNVGHTEITSFLTSFSKVISMFDTNRIPPQANFKEPNPAIHWEEYNMRTPTQIEGFTTRNPSGKRLASINASGLLGANGHVIAESPPPKAAKPSALPTGMPVLLMAAGLSPRSTTAIAADLSKLASEIPDELPILSNIFGRRARQLTWRAAAISTSDGPFVFPAPRFVPRGTPQLVFVFSGQGPQHIEMGRQLFKYYPVFRDSILKMDKVHVELTGKSIVKDLGFFGETRSSTALPDVWPVGLTVPSIAMIQMALVDLLAAFGIRPNLVFGHSAGEAAMSYTSGALPQELAMEIAVRRSQAMSIVEGSGGMAAVSCAPSVAREIVQEVLDEAGPDSGVLEIGCFNAPEAFTISGTHALLDKAVAIASGRGLFARKIKARVPGHCTLMEPCKERYVEQMEVAFSRYPGAHVPVVPTFSTQTGARWESEFTPEYMWNNGRVPVQFEQTVTAVVQEMPEAIFVEIGPHPALSSYISGMGAKPDKVVCPMRRVKNVTGFNEIFELLTAVGNLSTLGVNTINFHAVNATDCLEISKPIPAYPFAPKTMPFYSESSELAVKMKRSRKGPLNYDTLAVNALTHPDLAEHVIKGEPILPATGFFEMIFEEGARTIWDIELRSLLPLLPEKVLNVNVKSDGHAWSIVSSSGGRNPRLHATGFMTTEVMDKDAGPIDLAAIRARTTPADISNLYAILNNTAAFGPLYRRIEACYEGDHEILYQVRGNAPELTAHYNYVFHPSLLDSCIHGLLHPVFTGNADKSVFYLPSHIGRVTLYDRAIEEAVPETLYSYVVPHDWTPDSIACDAFIVNERGERLVTLIDCVLSKHWTGAVPTRPDTSYEYIYQPLGLPAAELVKSEAQQQDYAFLDAIVAHADEKVAPPSANGHANGHANGSANGSAVGTVGEDRKVFEEIVQSIASDELELKASSILGLFSASLDAPVAAVRQILDHAAKSGKQVVRILDIGDATASLYKQINAFASEYPSLRVDYTACGHEHATLDLRLASYNVDNVSKQAGLSPSTYDVIIETHTLGFAAELDRSLEYLHGLLLPGGFLVALEANGSAQASGGKWIDQVFSPQGRWSGLRSGKQHHRLSQSEWSGQLQKAKFQVVDGAQDAENTLFLTLLAQKHSLSTVSASSAASSAKVEEPAVFSFDHSRVLDLQKTVLASMSSGASNTKLWIESTTGTFDGAVATGFARSLMRELVAVDVRLVLFDPAWKAESRIPAIRQLSTLPSLESEIVLDASGVVMVPRLRSYAPRAPDSLDTTKYWVVDETKTVVQPAQPLPGPHQVLVKISSLSEAEGGLRGIVGTVARSGSSQWPVGAHVVTVAPSALSNFTLVHEGQLAQAPQTADEHSTAKVALLLVFAALGLRLDSRPLQSLQQIKVVVIHTGTVASSLARLLEYLGVKPVLVAPSLPLLLPRLSPGDVIIGGLSAAFARTVPRINGVSVFNWEDPEQGALAAVAQNPWLVGTTVDAHLARALPQVSVEGSSLTPDQLLPSDFSVSQSLALADDKTYLVLGGIGSLGLQIAIWMYQKGARHIVLTSRTGVSRLAGTKNRSLRGAVEYLKTLPDLELRLEPCDASSEESLSKLISSLDRPLAGAMLTAAVMADGLFLKQSADTYPIPFKPKTDAYFAFEKVVDIKKLDFLLAVSSVAGFGAAGQTNYASANTGIEYLTARYPNAWSFVAPGIADSNVGFDLFTSTNSHLEQWESSTMNSYEICLCLEDGLLRMANNERISIYVPNLNWDAISQSVSESVLYNHLVKLDAATDELEVEDPYEVLQEIVLKFVDASEEEFERNVPLTSYGLDSLSAARMSTALKPYLAITQIQLLGDLSLDDLVEKMQATKHVAVEETAVSTAEKPFAWDAMHQPGQTILKFNIGSGTPLIILHGGAGDTAAFRAIQEQFSTPLWAIQPTPEAPLDTVDTLAQFYFEKIKEARPAGPYRIAGFSASSMVTLRLAQLLEANEDEIAQLTFVDHFPLFFTSAIHGFTEDHKTFEDLTAYGRKASVALVAECCRRDTATARRLYGENLVAASNGQPSATNAMESWEWIQKTTRMNLKQVVDFGGGWEAWASSDATTRMEAARRRMVEEIAKVKAPMNVMIANWGIRALINSEWTDLGISRGGREVRTQYYDAGHFDIFEKPDFSRNLEFDWVDPHPVHQLATMIHNPAMNDLRALFKILDTKALQVMADTISQNPVVGSEISRQRLFEVCKEFVRTQKHSTWTDEEYEHSKALFPTYFETTERISKVHPSIMESPAAAVGALYSDDMIDGFYRQNKVFTSMNQEAAKTFKALVSSPDFGKQRPIRVLEVGAGVGGLTKFLVEALCDMPNADVEYTVTDLSYTLASSLAESFSYKNMVAKMYDLSKKPSEQGLQLGHYDVITGLNVIHAVPDLNATLTDLHSLLAPGGRILIVDTDGTARTSNPPRPGAIWNDFIWGSFQGWFGYTDDRTHCTIDEDEWRKRLTATGYSNVQVCHEDAGTCILFEAEKV",
    "output": "Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of strobilurin A, an antifungal polyketide that contains a key beta-methoxyacrylate toxophore that targets the complex III of the mitochondrial electron transport chain . Strobilurin biosynthesis begins with construction of benzoyl CoA by step-wise elimination of ammonia from phenylalanine by the phenylalanine ammonia-lyase str11, oxygenation by str8 and retro-Claisen reaction to form benzoic acid, which is activated to its CoA thiolester benzoyl CoA by the dedicated CoA ligase str10 . Benzoyl CoA forms the starter unit for the highly reducing polyketide synthase stpks1 that produces the polyketide prestrobilutin A . The FAD-dependent oxygenase str9 then catalyzes the key oxidative rearrangement responsible for the creation of the beta-methoxyacrylate toxophore . Str9 performs epoxidation of the 2,3 olefin of prestrobilutin A, followed by Meinwald rearrangement to furnish the aldehyde intermediate (Probable). Rapid enolization of the aldehyde intermediate would give the beta-methoxyacrylate skeleton and methylations catalyzed by str2 and str3 complete the synthesis and lead to the production of strobilurin A (Probable). The short-chain dehydrogenase stl2 and the dehydrogenase str4 play a role in the shunt pathway leading to the production of bolineol . The cluster encodes no obvious halogenase gene that could be involved in production of strobilurin B, nor any obvious dimethylallyl-transferase that could be involved in the production of strobilurin G (Probable). It is possible that unknown proteins encoded in, or near, the cluster (such as str1 or stl1) may form new classes of halogenases or dimethylally-transferases, or that the responsible genes are located elsewhere on the genome (Probable). Similarly, proteins encoded by str5/str6 hydrolases appear to have no chemical role in the biosynthesis of strobilurin A (Probable). Finally, no obvious self-resistance gene is found within the cluster (Probable)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFEQRVNSDVLTVSTVNSQAQVTQKPLRDSVKQALKNYFAQLNGQDVSDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN",
    "output": "Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNREEQLGILESLLFAAGDAGLSTEQLTEVMEITHIEALNLLELLSERYNGSADRGLILLELAGTFQLATKKAHADYLRKLVEVPSNTVLSQASLETLAIIAYRQPVTRMEVDEVRGVQTDGPIRTLVAKGLVTDKGRVDGAGRAKLYVTTSEFLDAFGLNSLEDLPKLADPAAEEPDQNEMDLFFDRFNQSKEQEEE",
    "output": "Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSDRHLYGSDHSYLSSKPSCSSCRRQSSTSQKNECMTNPGSIVLTQRWTVCNFESLLKLSRPGSCLRSTVFKDDAVPDACWQLCLYPGGKREENANNVSLFLKMSATSPSKEVVLKAEYRFYFLDDNDEPKFSNVNVGEFHAKPPKGGHSWGLRNIPTQKVQNSIRQDKSLVISCHIELIPDASKVPCKRVPITPSIEMPFAQIPRAHVESELEMLASGDGTDMTIVAGPLDGEREQFRVHAYKLRAHSDVFQMMLSHTEMRENQEKRIEILDFSPTSVRAMVEFIYAGVIKSDIDVYQAVDVMQIAEKYQILALKMTCEQHLLDRLNVNNVLECITHAERYNTDVLYDACVDFAIHNRQHVMALTSWRNFISDEPVLASNLLEKMVKSNDNSSPPVKKPRV",
    "output": "Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR",
    "output": "Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNPKCSLILLSGGKGERFGANQPKQYLPFQGQPLILHALNSALLIPEINEIIVVCDASYEHIFEGYSVKFAPAGMRRQDSVFSGLHHVTNPWVLVHDGVRPFIYPDEVSELIVIAQQTGAATLVSNVPYTIKQRNPVKTLDRDSLSIVHTPQCIKTEILLEGLELADREQITLVDDTQAAELLGIPVSLVSNKHPQIKITYPEDLTIAHALL",
    "output": "Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSDSRLLPTGSSPLEVAAAKACAEIEKTPVSIRELWNPDTCPANLLPWLAWAFSVDRWDEKWPEATKRAVIRDAYFIHCHKGTIGAIRRVVEPLGYLINVTEWWENSDPPGTFRLDIGVLESGITEAMYQEMERLIADAKPASRHLIGLNITRDIPGYLFAGGVAYDGDVITVYPG",
    "output": "Baseplate protein that may be part of the wedges of the baseplate. Plays a role in tail assembly."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLKRKLGPEDLRRLETPAIERESHGQTSAKSSVPDSASTVAVDFAGVTKSYGNKIVVDELSFSVASGECFGLLGPNGAGKSTIARMLLGMTCPDAGTITVLGVPVPARARLARRGIGVVPQFDNLDQEFTVRENLLVFGRYFGMSTRQSEAVIPSLLEFARLERKADARVSELSGGMKRCLTMARALINDPQLIVMDEPTTGLDPHARHLIWERLRALLARGKTIILTTHFMEEAERLCDRLCVLEKGRNIAEGGPQALIDEHIGCQVMEIYGGDPHELLSLVKPHSQRIEVSGETLYCYAPDPDQVRTQLQGRAGLRLLLRPANLEDVFLRLTGREMEE",
    "output": "Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MATNVGGAVDNSRRSISDNRHDPEKPAELPDTLSGSETERPQDANPEAALDQQASDAAKAHDEGPPDGGTAAWMVVLGAWCCSFCSPGWINSMGSFQEYYQREPLKDYSSSEIAWIPSLEIFFLFGLGPIVGIIFDRYGPRPLIIGGTIFHVFGLMMASLAKTYYQFLLSQGVCSAIGVACLYSPALACISTWFLKRRGAAMGIMATGSSVGGVIFPIMITRMIERNGYPWALRTAAFLILGLQVIACLTVRPRQKPVPKKLPAGRLAAPFTEPAFALLLAGIFILTYGMYIPIDYLPLSGLQEAHMSVNMSQYLVAIMNAASLFGRLGAGYGADIIGRWNMFIIACGVTGISNLAVWIPATKSSITIGYAIMFGFASGAFVSLVGALPVSVSPIPELGYRMGIVFLVISIPALTMAPIGGAILQHASNGWVSLKVFAGVMCLVGSAIILGSRMLYTEKRLIKAF",
    "output": "Efflux pump that may be involved in the secretion of fujikurins ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTRMRVHELAKELNMDNKDLIDRILKLGIQVKNHMSTLTDSAVLKIRQQFSEAKTETVEEKRIGRAVIRRRKKLTEGESAAAPAEGEERVASEALPVEAEMPAQPVEAPELIAEPISKLPPEVGVAQPQLPEEPEPAPEPLIPAVKPEEAAASELAVEPQTVVPPVAAPAAEVKPARPPMEAPAPARKPPEEKETKVKHAEPESLAEPLPSPAPVELTLVPAESAAGQVAERTDEEEEEDDKARPKKAKKRRRKKVRKDEPARIIKLPEIIPEEPEEEAVLPAHLATRIQVKTEEVEVKEAPRKKRPRPEEFEKEAAERKAKGTRRKEVFEREDLYSKQEIAAQDDRGRLKGDKRRPFAKEPARPEIAVVKPGKRKIRVDEAITVANLAKQMGIKATELIKKLLLLGLPANINQAVDFDTAALLASEFEFEVEKTGFEEEELLQVREDRVEDLIRRPPVITVMGHVDHGKTSLLDAIRDTNVIGGEAGGITQHIGAYYVMLPNGNVVFLDTPGHEAFTSMRARGAKVTDIVILVVAADDGVMQQTIEAINHAKAAEVPIIVAINKVDKPNANIDRVKRELAEHGLIPEEWGGNVTMVGISAKKRTGIEELLEMVLLQAELLELKANPAKPARGRVIEAKLDKGRGPVATILIQEGTLRTGDVYLCGVNSGRVRNMFSDRGQRLDEAGPSMPVEVLGLSGVPNAGDDFITLPDERQAKMIAEHRLVKLREKELSRTSKVTLESLFEQIQEGEIKELNLILKADVHGSLEAITDSLLKLSTPEVKVSLIHFGTGAVIETDVMLASASNAIVIGFNVRSETKVQELADQENVDVRYYDVIYQLLSDVKDAMVGMLEPVFKENVIGRAEVRQTFQVPKIGMIAGSFVLEGRVERNAKCRVLRDHVVTYDGKISSLRRFKDDAKEVKAGFECGIGVENFNDIKVGDILEVYELQEMKPVLESPPGDK",
    "output": "One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEMKPKYDPREVEAGRYEEWVKNGYFKPSEDKSKETYTIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEQGITRYDLGREKFLEQAWDWKEEYASFIRAQWAKLGLGLDYSRERFTLDEGLSKAVKKVFVDLYNKGIIYRGERIINWDPKARTALSDIEVIHEDVQGAFYHFKYPYADGEGFIEIATTRPETMLGDTAIVVNPNDERYKDVIGKTVILPIVGRELPILADEYVDIDFGSGAMKVTPAHDPNDFEIGQRHQLENIIVMDENGKMNDKAGKYEGMDRFDCRKQLVKDLKEQDLVIKIEDHVHSVGHSERSGAVVEPYLSTQWFVRMEDLAKRSLDNQKTDDRIDFYPQRFEHTFNQWMENIRDWTISRQLWWGHQIPAWYHKETGEIYVGEEAPTDIENWQQDEDVLDTWFSSALWPFSTLGWPDLESEDFKRYYPTNALVTGYDIIFFWVARMIFQGLEFTDRRPFNDVLLHGLVRAEDGRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVESVWNFINKIWNGARFSLMNIGEDFKVEDIDLSGNLSLADKWILTRLNETIATVTDLSDKYEFGEVGRALYNFIWDDFCDWYIEMSKIPMNSNDEEQKQVTRSVLSYTLDNIMRMLHPFMPFVTEKIWQSLPHEGDTIVKASWPEVRESLIFEESKQTMQQLVEIIKSVRQSRVEVNTPLSKEIPILIQAKDKEIETTLSQNKDYLIKFCNPSTLNISTDVEIPEKAMTSVVIAGKVVLPLEGLIDMDKEISRLEKELAKLQSELDRVDKKLSNENFVSKAPEKVINEEKRKKQDYQEKYDGVKARIEQLKA",
    "output": "Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQIVRNVPDLRAARAALTDGGRARLALVPTMGALHEGHLSLVRAAREAGHVVAASIFVNPTQFGPNEDFTRYPRDPERDCALLAEAGCALAWLPEVSTMYPPGDATSVEVAGLSVVLEGAVRPGHYRGVATVVVKLLGQVRPDAAYFGEKDWQQVQVIRRVAADLFLPVEIVVGPTLREKDGLAMSSRNRYLDPADRARAPLLHQVLRRVRAALRDGEPAAAALAAGRRALAEGGFIVDYLELVDAGTLAPLTAPDDGARLLAAARLGTTRLLDTVAV",
    "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVEKKPAVRSQDPGQRRVLDRAARQRRINRQLEALENDNFQDDPHAGLPQLGKRLPQFDDDADTGKKKKKTRGDHFKLRFRKNFQALLEEQNLSASEGPNYLTACAGPPSRPQRPFCAVCGFPSPYTCVSCGARYCTVRCLGTHQETRCLKWTV",
    "output": "Plays a role in chromatin remodeling by promoting the incorporation of histone variant H2AZ1/H2A.Z into the genome to regulate gene expression . Promotes SRCAP complex-mediated deposition of histone variant H2AZ1 to lymphoid fate regulator genes, enhancing lymphoid lineage commitment . Recruited to the promoter of the transcriptional activator MYOG at the early stages of muscle differentiation where it mediates binding of histone variant H2AZ1 to chromatin and induces muscle-specific gene expression (By similarity). Maintains hematopoietic stem cell (HSC) quiescence by determining the chromatin accessibility at distal enhancers of HSC quiescence genes such as PTEN, FSTL1 and KLF4, enhancing deposition of H2AZ1 to promote their sustained transcription and restricting PI3K-AKT signaling inhibition . Plays a role in intestinal stem cell maintenance by promoting H2AZ1 deposition at the transcription start sites of genes involved in intestinal stem cell fate determination including LGR5, TGFB1 and TGFBR2, thereby contributing to gene transcription . Promotes phosphorylation of the H2AZ1 chaperone VPS72/YL1 which enhances the interaction between HZAZ1 and VPS72 . Regulates the entry of male germ cells into meiosis by controlling histone H2AZ1 deposition which facilitates the expression of meiotic genes such as MEIOSIN, leading to the initiation of meiosis . Required for postnatal heart function through its role in maintenance of cardiac Ca(2+) homeostasis by modulating the expression of Ca(2+)-regulating proteins CASQ1 and ATP2A2/SERCA2A via deposition of histone H2AZ1 at their promoters . During embryonic heart development, required for mitochondrial maturation and oxidative metabolism by functioning through H2AZ1 deposition to activate transcription of metabolic genes and is also required to maintain the stability of the respiratory complex . In neural cells, increases deposition of the H2AZ1 histone variant and promotes neurite growth (By similarity). Plays a role in TP53/p53-mediated apoptosis induction by stimulating the transcriptional activation of several proapoptotic p53 target genes such as PMAIP1/NOXA and BBC3/PUMA (By similarity). Mediates cell cycle arrest induced in response to gamma-irradiation by enhancing recruitment of TP53/p53 to the promoter of the cell cycle inhibitor CDKN1A, leading to its transcriptional activation (By similarity). Recruited to the promoter of cyclin-dependent kinase CDK6 and inhibits its transcription, possibly by decreasing the acetylation level of histone H4, leading to cell cycle arrest at the G1 phase . Plays a role in lens fiber cell differentiation by regulating the expression of cell cycle regulator CDKN1A/p21Cip1 . Binds to transcriptional repressor NR1D2 and relieves it of its inhibitory effect on the transcription of apolipoprotein APOC3 without affecting its DNA-binding activity (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEVPTLSKTRKPPDLNEESLDLGIMIALFEIGSIPPVSCSSLPSLKSSDHEATEQRIAKKFESLLKEIKDIVKHVTSYEQKVTETKEPFKETNMFEVSELREKIIELDEINKELVKKLLASLDLGKKENAKKQEMRLDNQNSEDTVQDCSGDLVNCSKGQKALPETQLSKEKAKHGFPHIQEENIRLRNNMERLLQEAEHWSVEHTELSKLIKSYQKSQNDIKTLKNNGTHSPTQTNNESAKQELEEQVKRLKEDTYSLHLIATLLENECQILEQRVELLDELHHQKEEPLQGEPMQINHEQSDKEQKLPEAEKVKIHEKNMPEVEGTFHKRDQFFTSLDICHNKKAHNNQFNTRIAKRALVVKRPASSLS",
    "output": "Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAAQAAAAAQAAAAAQAAAAQAAQAEAAESWYLALLGFAEHFRTSSPPKIRLCVHCLQAVFPFKPPQRIEARTHLQLGSVLYHHTKNSEQARSHLEKAWLISQQIPQFEDVKFEAASLLSELYCQENSVDAAKPLLRKAIQISQQTPYWHCRLLFQLAQLHTLEKDLVSACDLLGVGAEYARVVGSEYTRALFLLSKGMLLLMERKLQEVHPLLTLCGQIVENWQGNPIQKESLRVFFLVLQVTHYLDAGQVKSVKPCLKQLQQCIQTISTLHDDEILPSNPADLFHWLPKEHMCVLVYLVTVMHSMQAGYLEKAQKYTDKALMQLEKLKMLDCSPILSSFQVILLEHIIMCRLVTGHKATALQEISQVCQLCQQSPRLFSNHAAQLHTLLGLYCVSVNCMDNAEAQFTTALRLTNHQELWAFIVTNLASVYIREGNRHQEVLYSLLERINPDHSFPVSSHCLRAAAFYVRGLFSFFQGRYNEAKRFLRETLKMSNAEDLNRLTACSLVLLGHIFYVLGNHRESNNMVVPAMQLASKIPDMSVQLWSSALLRDLNKACGNAMDAHEAAQMHQNFSQQLLQDHIEACSLPEHNLITWTDGPPPVQFQAQNGPNTSLASLL",
    "output": "Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodim. eric complex (also known as cohesin loading complex) with NIPBL/SCC2 which mediates the loading of the cohesin complex onto chromatin Plays a role in sister chromatid cohesion and normal progression through prometaphase."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRYLPLTPEDRAQMLGVIGAPDVDALFADVPAAARNPAIGLAPHAGELEVERELSGLAALNRAAGAGPFFCGAGAYRHHVPATVDHIIQRSEFLTSYTPYQPEIAQGTLQVLFEFQTQVARLTGLDVANASMYDGSTACAEAVMMAQRVTRREKAILSGGLHPHYAATTQTIAHAEGMEIVRQPAAIDAEAAVIEAIDAETACVVVQTPNVFGVVTDVSKIAEAAHAKGALLIVVTTEAVAYGLLKSPGEMGADIAVAEGQSIGNALNYGGPYVGLFACREKFVRNMPGRLCGETVDAEGRRGYVLTLSTREQHIRREKATSNICTNSGLCALAFSIHLSLLGGKGLSQLARVNHARARELKAAVEAAGLEVLTPRFFNEIAVRTKGPAADLVERLLADGVVAGVPFSRLDPGAGLDDVLLLCATETTTSDDIAALKDALAR",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MELKEYLDYLVEFIKETVKKANAKGVVIGISGGIDSAVVACLAKKAFPNDYTAVWMPIESSDEDYKCKQELIDQCGIKAIDVELKETFLSFKKAIKDSTTPEHKLAIANAKARLRMTTLYTVAQTNSYLVLGTDNLDEWHIGYFTKFGDGGVDMVPLVHLLKREVREAARILGVPTSIINRAPTASLWEDQTDESELGITYDQIDAYLAGEINDENVKSRVDHLHKISEHKRNGAVAPKEFKRK",
    "output": "Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTQIGTPLSPTATRVLFCGSGELGKEVVIELQRLGVEVIAVDRYENAPAMQVAHRSHVINMLDGAALRAVIEAEKPHFIVPEIEAIATATLVELEAEGFTVIPTARAAQLTMNREGIRRLAAEELKLPTSPYHFADTFEAYSKAVEDLGFPCVVKPVMSSSGKGQSLLKSTDDVQKAWDYAQEGGRAGKGRVIVEGFIDFDYEITLLTVRHIGGTTFCAPVGHRQEKGDYQESWQPQAMSPVALAESERVAKAVTEALGGRGMFGVELFIKGDQVWFSEVSPRPHDTGLVTLISQDLSQFALHARAILGLPIPLIRQFGPSASAVILVEGQSTQTAFANLGAALAEPDTALRLFGKPEVNGQRRMGVALARDESIEAARAKATRASQAVNVEL",
    "output": "Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLRFAVIGHKAVSTPDFSLNDMPGGAGRMDVLCRCINASFFLSHDLRRDTECFLILKGGEQADPANTVTLRFSGEKIKSLNPDERSAGALIKKALVTIPEEEYQRAAPGISIRKSGLAKLLEEHPFAVLDENGEDIRTAETLPENFILSDHQNFTEEEMELIKDLPKYSVGPRVLHADHTIIIILNEFDRRGEQA",
    "output": "Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSASAAVSSTCAAASSTTSRRSSSSPASRVQATPRRSLPSRLVASRTSPRSPVVPPVYATASPGGAGGTTAAAARKKLLIFDAEEYLAESLAKYTARLSGEAVAERGAFTVALSGGSLIKALRKLTESPYLEAVEWSKWHVFWVDERVVPKDHADSNYKLAMDGLLSKVPIPASQIYAINDTLSAEGAADEYETCLKQLVNDGVVAISEVTGFPKLDLMLLGMGPDGHVASLFPGHPVVNENLKWVSYIKDSPKPPPERITFTFPLVNSSAHIALVVTGAGKAGAVHKAFSDKQSSSDLLPVEMVSQQEGVLTWFTDKPAVSMLSSI",
    "output": "Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "GSSGLISMPRV",
    "output": "Mediates visceral muscle contractile activity (myotropic activity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAGAIENARKEIKRISLEDHAESEYGAIYSVSGPVVIAENMIGCAMYELVKVGHDNLVGEVIRIDGDKATIQVYEETAGLTVGDPVLRTGKPLSVELGPGLMETIYDGIQRPLKAIKEESQSIYIPRGIDTPALDRTIKWQFTPGKFQVGDHISGGDIYGSVFENSLISSHKILLPPRSRGTITWIAPAGEYTLDEKILEVEFDGKKSDFTLYHTWPVRVPRPVTEKLSADYPLLTGQRVLDALFPCVQGGTTCIPGAFGCGKTVISQSLSKYSNSDAIIYVGCFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRETMYSVVQKSQHRAHKSDSSREVPELLKFTCNATHELVVRTPRSVRRLSRTIKGVEYFEVITFEMGQKKAPDGRIVELVKEVSKSYPISEGPERANELVESYRKASNKAYFEWTIEARDLSLLGSHVRKATYQTYAPILYENDHFFDYMQKSKFHLTIEGPKVLAYLLGLWIGDGLSDRATFSVDSRDTSLMERVTEYAEKLNLCAEYKDRKEPQVAKTVNLYSKVVRGNGIRNNLNTENPLWDAIVGLGFLKDGVKNIPSFLSTDNIGTRETFLAGLIDSDGYVTDEHGIKATIKTIHTSVRDGLVSLARSLGLVVSVNAEPAKVDMNGTKHKISYAIYMSGGDVLLNVLSKCAGSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITLSDDSDHQFLLANQVVVHNCGERGNEMAEVLMEFPELYTEMSGTKEPIMKRTTLVANTSNMPVAAREASIYTGITLAEYFRDQGKNVSMIADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGKAVALGSPDRTGSVSIVAAVSPAGGDFSDPVTTATLGITQVFWGLDKKLAQRKHFPSINTSVSYSKYTNVLNKFYDSNYPEFPVLRDRMKEILSNAEELEQVVQLVGKSALSDSDKITLDVATLIKEDFLQQNGYSTYDAFCPIWKTFDMMRAFISYHDEAQKAVANGANWSKLADSTGDVKHAVSSSKFFEPSRGEKEVHGEFEKLLSTMQERFAESTD",
    "output": "Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments .; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAMFSHRLRRIVVAAPSYFQRFSTLSRPSDFTPVPSLLPRSVVKQSTAINRSPARLFSTTQYQYDPYTGEDSFMPDNEGCDFNHWLITMNFPKDNLPSREEMISIFEQTCAKGLAISLEEAKKKIYAICTTSYQGFQATMTIGEVEKFRDLPGVQYIIPDSYIDVENKVYGGDKYENGVITPGPVPVPTKEGFDSLKKESKPEQEEAEIILTPPDEGKTSGQVQGQGSLTLPDQRSVKERQGTLALVQGQGQRSGMSILGQGQGEGRRMSIPGQWQSRGQGNSFQGSFKQSQGTLPVRKGQTQISDEIPSFQGNVKQRQEMPIHGQGQAQRSQMPSSQGTLRQGQAQGSQRPSNQVGYNQGQGAQTPPYHQGQGAQTPPYQESPNNYGQGAFVQYNQGPPQGNVVQTTQEKYNQMGQGNYAPQSGGNYSPAQGAGSPRFGYGQGQGGQLLSPYRGNYNQGQGTPLPGQGQEGQPSYQMGFSQGLGAPVPPNQVIPGNYGQWAFVNYNQGPPQGNFLQGPQQNHNQGGQWNYSPQNGGHYGPAQFGQWYPGPPQGQGIQWPQYQLSYNQGQGTPFSGQCRCPNCGMTSYQGYNNQGQGTHIPEQWEGQDYAVLSYQASYNQAHGAQAPPYHGNYNQATPGGYGQGTSANFNQRFPVNPANYNMQNGGNYGPPHGLAGNPGFRQGFSGQGQNQTFQQDDQRNVAGDLRNNNPVDPTETRKPNSRI",
    "output": "Involved in organellar RNA editing. Required for the processing of few RNA editing site in mitochondria."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKILLAIALMLSTVMWVSTQQPQRVHTYCGRHLARTLADLCWEAGVDKRSGAQFASYGSAWLMPYSEGRGKRGIVDECCLRPCSVDVLLSYC",
    "output": "Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAHPSGSGGTSFAPTPTHPHHLSRETSRDELEMAESLRLLNQTHDHQKPRAEATSQEQQQQQQQQQQQQQQQQQQQQQQHAQEDPRSEIYHSLEDAVPIADGPPTPSTAASLQIPNMNYETPNASITGQVCSNCKTTQTPLWRRSPAGETVCNACGLYMKARNQSRPVNLKRNTQTQPTMSVQQSPTPGSTDGSRTCAGNVAGSPRVATYVAADQMAAGTCPGGGRCNGTGGQQGCSGCPAFNNRVSKTAKFALAQANAAPGENRGGSDAASSTSAASASTSAIPACQNCGTTITPLWRRDDAGHIICNACGLYYKLHGTHRPVAMKKQEIKRRKRIVPAADTSSQAPSSVANYSPPQRPSQTPAFEHSVSPDPSTALESREAYTPEPPRGPIAVDFTHYYSNSSVTSNPVALTPTVQPSAPSPRKRSRSATLDPEEPVNPLPHRPNAISAILNPSQTEVDANIDPSLSVPLRTSGGTSPNFTLSPEEKAAKRERLKREAEAMRLELERRQKELEELEND",
    "output": "GATA-type transcription repressor that regulates iron- acquisition genes through specific binding the GATA sequence elements of target promoters . SRE1 targets repressed under iron-replete conditions include genes encoding a number of key iron-regulated factors such as those involved in siderophore biosynthesis NPS6, SIDA2 and ABC6, as well as the high-affinity iron permease FTR1, the catalase CAT1, and the superoxide dismutase SOD1 encoding genes ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDGIKYAVFTDKSIRLLGKNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKGRRMGPIMGQTMHYRRMIITLQPGYSIPPLRKKRT",
    "output": "Binds to 23S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDTFESVKAVVVEQLSVDANEVKPESRFIEDLNADSLDVVELVMALEEKFSIEIPDEEAEKIKTVKDVVAYIEANK",
    "output": "Carrier of the growing fatty acid chain in fatty acid biosynthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKRDYYEILGVSKNATKEEIKKAYRKLSKKYHPDINKEPDAAEKFKEIKEAYEVLSDDQKRAHYDQFGHADPNQGFGGFRSDDFDFGGFSGFSGFDDIFSTFFGGGRRRDPNAPRAGADLQYTMTLTFEEAVFGKETDIEIPREETCNTCHGTGAKPGTKKETCSYCHGTGQISTEQSTPFGRIVNRRTCPYCGGTGQYIKERCTTCGGTGRVKRRKKIHVKIPAGIDDGQQLRVAGQGEPGINGGPPGDLYIVFHVEPHEFFERDGDDIYCEIPLTFAQAALGDEIEVPTLHGKVRLKIPAGTQTGTKFRLKGKGVPNVRGYGYGDQHVIVRVVTPTKLTEKQKQLLREFDQLGGSSMHQGPHGRFFEKVKKAFKGES",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNPTFILAALCLGIASATLTFNHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHSFTMAMNTFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVADNGGLDSEESYPYEATEESCKYNPEYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFMFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNSKYWLVKNSWGEEWGMGGYIKMAKDRRNHCGIASAASYPTV",
    "output": "Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Plays a critical for normal cellular functions such as general protein turnover, antigen processing and bone remodeling. Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). In neuroendocrine chromaffin cells secretory vesicles, catalyzes the prohormone proenkephalin processing to the active enkephalin peptide neurotransmitter (By similarity). In thymus, regulates CD4(+) T cell positive selection by generating the major histocompatibility complex class II (MHCII) bound peptide ligands presented by cortical thymic epithelial cells. Also mediates invariant chain processing in cortical thymic epithelial cells. Major elastin-degrading enzyme at neutral pH. Accumulates as a mature and active enzyme in the extracellular space of antigen presenting cells (APCs) to regulate degradation of the extracellular matrix in the course of inflammation (By similarity). Secreted form generates endostatin from COL18A1 (By similarity). Critical for cardiac morphology and function. Plays an important role in hair follicle morphogenesis and cycling, as well as epidermal differentiation (By similarity). Required for maximal stimulation of steroidogenesis by TIMP1 (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNNYETVFILTPVLSDAQMKEAVDKFTGLLKQEGAVIVNEENWGLRKLAYPIQKKSTGFYQLVEFQANPDVIAKLETNFRRDERVIRFLTFRQDKFAAEYAAKRRSLKAKTEEVKEA",
    "output": "Binds together with S18 to 16S ribosomal RNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKPMSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVFEPINKRIKQANSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYTKGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMMIFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSSRKDVTPSQNMEQANLPKKIKSNRNAGKQRKR",
    "output": "Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDSLRIIFAGTPDFAARHLDALLTSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVADLHADVMVVVAYGLILPKAVLDMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLACPITAEDTSGSLYNKLAELGPQGLITTLKQLADGTAAPEAQNEALVTHAEKLSKEEARIDWSLSAVQLERCIRAFNPWPMSWLEIDGQPVKVWQASVIEDATQSLPGTILAATKQGIQVATGKGILNLLSLQPAGKKAMSAQDLLNSRREWFIPGNRLA",
    "output": "Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYFDYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLSGKLSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA",
    "output": "Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIAIIDYGMGNIRSVEQALKYIGAEYIVTSNKKEILRSDGVILPGVGAFPKAMDVLEERDLVCVLKEVCDIGKPLLGICLGMQLLFERSEELKDCSGLGLLPGEIRKLKVSYKIPHMGWNELRKEREFPLWNGLVDGSFVYYVHSYYADCPDEIVCGVSDYGMQVPGFVAKGNVFGAQFHPEKSGEIGMQILKNFQGVVEAWKSSQLSI",
    "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEDEISSFFESSPPQKNMEEILENLNEFIKLNSSSQGGRRIVCVTSGGTTVPLEQRCVRYIDNFSSGNRGAASTENFVKAGYAVIFLYRRGTCQPYCRSLPDDPFLECFEFSDKTNIQVHTSHLEAVKMAVMDQQTAVAEGSLLKLPFSTIYEYLQMLRLIAEALKDVGPCSMFYLAAAVSDFYVPWKSMTEHKIESGSGPLDIRLAQVPKMLSVLRSNWAPKAFCISFKLETDSKILMEKATKALRKYKVHAVVANELSTRKEEVVVVSSSGNVVVRRECDKPESFVEDNLIRLIVDRHSTYIKESHN",
    "output": "Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MYAIVRSGGRQHKVAVGDIVEVDKISTAQVGDTVELSTLLVVDGDAVTSDPWVLAGIKVQAEVVDHHKGAKIDILRYKNKTGYRRRQGHRQQYTAIKVTEIPTAAK",
    "output": "This protein binds to 23S rRNA in the presence of protein L20."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTVHIGAAPGDIAETVLMPGDPLRAKWAAERFLENPVCVNEVRGMLGFTGMWRGNRVTIHGSGMGMPSLSIYANELLRDYGAKTLIRIGSCGAMQADVKLRDVILAMTASTLSTPSSGIFRELNYAPCADYGLLQAAYKAAEGKGSPIHVGGIYSSDVFYDERPDLNEQMVRHGVLAVEMEAAELYTLAARHKARALAVLTVSDHLLTEEALPSEERQSSFSDMVEIALEAAFS",
    "output": "Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNIVNVSLVKPTVYVYSRVKNLNSSEGVPDLLV",
    "output": "Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis (By similarity). Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVIGYVLLFGINMMSTSPLDSIHTITDNYARNQRQKKYQEEAIPALRDISISEVNQMFFLAAKELYTEN",
    "output": "Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARYDLVDRLNTTFRQMEQELAAFAAHLEQHKLLVARVFSLPEVKKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQVDNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRTLTVLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQDIAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGARVPDVGELLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD",
    "output": "Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFMVNLLMLVIPVMLAMAFLTLLERKTLGYMQFRKGPNVVGPNGLLQPFADAMKLFIKEPLQPLTSSTSLYIIAPTLALSIALIMWTPLPIPYPLVNINLGVLFILATSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLCILLMSGSFTLSTLIKTQEHTWLLLPSWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIIMMNALTATIFMSAIHSMNFPEFFSINFTLKTLLLTTIFLWVRASYPRFRYDQLMHLLWKNFLPLTLAMCMWHTALPIFLANIPPQT",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTLKVPCPQCQKTVVWQASSEFRPFCSKRCQLIDLGEWAEESHKISQNIQVDTVLSEEMLDAMEDEFLLNNKFFVEPE",
    "output": "Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVLEYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQAATPAKQTNIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTLKNHTLPTALQRSLDVADFKTPVQKVTLKRLNNDTQLIITTTGNWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVSGKMTLSLKDVPWDQALDLVMQARNLDMRQQGNIVNMAPRRAACQRQSLLTSGKRHCRSGRAVFPKLPIEIQKCGRIPQHPALDNADTTGNRNTLVSGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGRKKLKNETSAFGWGVNSGFGGGDKWEAKPKSTCRLPCRKQHFAGARDFSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTTRSGGGNSTNTELKKAVLGLTVTANITPDGQIIMTVKINKDSPRQCASGNNTILCISTKSLNTQAMVENGGTLIVGGIYEENNGNTLTKVPLLATSPLSATSLKHSGKNRPPRTADFQLPPREL",
    "output": "Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "GGCCSHPACAANNQDYC",
    "output": "[Alpha-conotoxin AnIB]: Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This synthetic toxin blocks rat alpha-3beta-2/CHRNA3-CHRNB2 nAChRs (IC(50)=0.3 nM) and alpha-7/CHRNA7 nAChRs (IC(50)=76 nM).; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARVTVQDAVEKIGNRFDLILTAARRARQLQLNQSAPLVPEDNDKPTVIALREIEKGLINQDIMDAQEFQKMAKVQETEEAAVALITE",
    "output": "Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDPGIANHTLPEEFEEVVVPEMLEKEVGAKVDVKPTLTTSSPAPSYIELIDPGVHNIEIYAEMYNRPIYRVALFFSLFLIAYAYGLDGNIRYTFQAYATSSYSQHSLLSTVNCIKTVIAAVGQIFFARLSDIFGRFSIMIVSIIFYSMGTIIESQAVNITRFAVGGCFYQLGLTGIILILEVIASDFSNLNWRLLALFIPALPFIINTWISGNVTSAIDANWKWGIGMWAFILPLACIPLGICMLHMRYLARKHAKDRLKPEFEALNKLKWKSFCIDIAFWKLDIIGMLLITVFFGCVLVPFTLAGGLKEEWKTAHIIVPEVIGWVVVLPLYMLWEIKYSRHPLTPWDLIQDRGIFFALLIAFFINFNWYMQGDYMYTVLVVAVHESIKSATRITSLYSFVSVIVGTILGFILIKVRRTKPFIIFGISCWIVSFGLLVHYRGDSGAHSGIIGSLCLLGFGAGSFTYVTQASIQASAKTHARMAVVTSLYLATYNIGSAFGSSVSGAVWTNILPKEISKRISDPTLAAQAYGSPFTFITTYTWGTPERIALVMSYRYVQKILCIIGLVFCFPLLGCAFMLRNHKLTDSIALEGNDHLESKNTFEIEEKEESFLKNKFFTHFTSSKDRKD",
    "output": "Involved in the transport of siderophore ferrioxamine B and so has a role in iron homeostasis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSILFNAYPLARPALFAMDAETAHEVTLASLQRAYDCGTTRRWLHDQPQLPTTLMGMTLRNPVGLAAGLDKNGAFIDALGNLGFGFVEVGTVTPRAQSGNPKPRMFRLPKANALINRLGFNNQGLDAFLANVTRSRFRSQGGILGLNIGKNADTPIERAADDYLIGLAGVYPHADYVTVNISSPNTKNLRALQGGDELSQLLAALRDKRAELAQQHARQVPLVVKIAPDLSQEQIDIIADTLLSNGVDGVIATNTTLSREAVQGMPHAAETGGLSGAPVHELSLAVIERLRQRVGSALAIIGVGGILSGQQAREKIAAGADAVQLYTGLIYRGPALVGECVGTLKNTAR",
    "output": "Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGLSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLVLRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF",
    "output": "Required for maturation of 30S ribosomal subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNNYETVFILTPVLSDAQMKEAVEKFTNLLKAQGAEIVNEENWGLRKLAYPIDKKTTGFYQLVEFKADPSVIATLELNFRRDERVIRFLTFRQDKYAAEYAAKRRNLKSSKETVKENN",
    "output": "Binds together with S18 to 16S ribosomal RNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLLQKTLCIVKPDGVRRGLIGDVVSRFERVGLKMVAAKMLIVDESLAKKHYLYDDIVFRHSEAVWNSLIKFISNSPVFTFVVEGVESIEVVRKLCGATEPKLAIPGTIRGDFSYHSFKYSNEKGFSIYNVIHASANEADAMREIPIWFKDNEILNYKRDDECEHYYC",
    "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVKAKKQYGQNFLIDKSVLAKIIQAIPKEMNNIIEIGPGLGDLTQELLKISQVKAYEIDNDLIPILKKKFQKELECGKFNLIHQDASEAFNPSLDEKPYFLVANLPYYVASHIILKALEDKNCLGLIVMAQREMAEKFCAKEGNSEFSSLGVLSAMICERKILFDVDPQCFNPPPKVMSAVMSLIKTKDFDELCEIENFKNFLKDCFKAPRKQLLGNLKTYKAKVLEVLSTLGLKENIRPHEICVDLYLKIYDKLKDEYGRKQRDK",
    "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSFSFGFTSNDFDDDELVAQPETFVESSKENENTTAYINPLDSDFLSQAGVVQPNVEDLGTILESLKDVRLTFEEFQSPIYRKPLIKRELFDVKHQLMLETDAQSNNNSTELDILLGDTSEDLRKNIYEGGLKSWECSYDLVDLLSENVDRISNDIDAVVEIGCGTALPSEFLFRSALLRNDRSKGLKFVLTDYNASVLRLVTIPNLVITWAKTVLTKEQWYALQKDECEDIPINNEELLLTSKLLAAFYDDVQSRNISVTLISGSWGRKFSNLIHEVLSGSQKVLSLSSETIYQPDNLPVIAETILDIHNLPQTDVKTYVAAKDIYFGVGGSITEFEAYLDDKINSEHLPIHSERFKVNSGLKRSIICIETNKAIR",
    "output": "Protein-histidine N-methyltransferase that mediates methylation of RPL3 at 'His-243' . Methylates ribosome-associated RPL3, but not free RPL3, thereby regulating 60S subunit assembly . In addition to RPL3, mediates His methylation of other proteins ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKIRILTIGQKMPAWVLTGFEDYFKRIQPFVQTQVIKLPMAKRGKNDSEADILKYCQIEGESILNALKPNETLIALEVGGRELSTEKLADTMKQWMLEGNDVALAIGGPDGLSDQVRKAAAWHWSLSKLTMPHPLVRILLIEQLYRAMSINHNHPYHRA",
    "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDGEFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALHEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGSLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR",
    "output": "Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDRQTQIPAGGGREDDHDDQVQSAGQVQVNTEGVDDLLDEIDGLLENNAEEFVRSYVQKGGE",
    "output": "Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLNPYLLRNELHLTAKKLLKKGYKLNISKISSMEEKRKTLQIQTENLQFKHNALSNLFKENKNIKNKNELLRHQVIQSSKDLNASKIELNSLKEKIHHFSMCIPNIPSDDVPEGNTSINNKEIKYWGQKKKYDFEIQDHIELGKKFNELDWKSSAQMSGSRFVIMKGKIALLHRALSQFMLDLHTLKHGYIESYVPYLVHSEALYGTGQLPKFSDDLFHINLTDKKKYILIPTGEVPLTNLVYDQIIDEKDLPIMLTAHTPCFRSEASSYGRDTKGLIRLHQFDKVELVQIVKPEKSYEALEKLTNHAEKVLQLLNLPYRKMLLCTGDTGFAAVKTYDLEVWFPSEKKYREVSSCSNMSDFQARRIKARYRKKSEQKNFFVHTLNGSGLAIGRTLAAILENYQHSNGRIEIPKVLQKKYMQGLEFIN",
    "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTAITASMVKELRDRTGLAMMECKKALTEANGDIELAIDNLRKSGQAKAAKKAGNIAADGAITIVQDGNKAVLVEVNCQTDFVAKDENFSNFSNAVAKAILASGETDAEKVAELKLEDGQSVEEARIALVQKIGENIQVRRAKIVEGENLAVYKHGLRIGVVVSYTGSAETGKGIAMHVAAFNPVAVSAEAVPADLVAKEKEIAEAKAIESGKPANIVEKMVSGSVEKYLNEVALDRQMYVIDNDKKVADVLKATATNIVEFVRFEVGEGIEKKAEMSFAEEVAAAQAAAK",
    "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSTILIAIIALAALAAVFGAILGFASIRFKVEADPIVDQIDSILPQTQCGQCGYPGCRPYAEAIANGDQINKCPPGGQATIEKLADLMGVEAEESAHDLDSKVKTVAFIHEDMCIGCTKCIQACPVDAIVGGTKALHTVIKDECTGCDLCVAPCPTDCIEMIPVETTTESWKWKLNAIPVVNITDAANAANVTDSIK",
    "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGITKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPAGLLTVPFLENVNKFQNPFRRPVATTVFLVGTVVALWLGIGATLPIDKSLTLGL",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRIVLITGISGSGKSVALNALEDAGYYCVDNLPPHVLPELARYLAEEGQHRLAVAIDARSSASLDEMPGLIRALSLEHDVRVLFLNASTQSLIQRFSETRRRHPLSGSPSHDANVGLLSSLEEAIERERELVAPLAEFGHQIDTSTLRANVLRTWVKRFIEQKNNDLMVMFESFGFKRGVPLDADLMFDVRALPNPYYDHELRPLTGLDQPVIAFLDALPIVHQMIDDIHAFLMKWLPHFREDNRSYLTVAIGCTGGQHRSVFIAETLAARLAHDANVIVRHRDAPVDVDASSRLVADVHRP",
    "output": "Displays ATPase and GTPase activities."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLKEFQEFALKGNMVDLAIGVIIGGAFGGLVNSIVNDIIMPIIGLITGGIDFSNMFIQLAGDPKTTLAAAREAGATIAYGNFITLLINFLIIAWVLFLVVKLMNRLKKREEAKPAPAAPSEEVLLTEIRDILAKQQKA",
    "output": "Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVLSSADKNNVKACWGKIGSHAGEYGAEALERTFCSFPTTKTYFPHFDLSHGSAQVQAHGQKVADALTKAVAHINDLPNALSDLSDLHAYKLRVDPVNFKFLSHCLLVTLACHHPEEFTPAVHASLDKFFSAVSTVLTSKYR",
    "output": "Involved in oxygen transport from the lung to the various peripheral tissues.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRIKNKIKKRIIELIDLAYITARKGDLELAREYIKLAEMYSRKGRVKIPLKYKRMFCRKCYTPLITGVTERRRIRSKILIRTCLICNWQRRYVLSRNKGSNKEN",
    "output": "Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVALKGIPKVLSPELLFALARMGHGDEIVLADANFPTSSICQCGPVEIRADGLDIPQLLEAVLRLLPLDTYVESPAAVMDLVPSDKEKGLQTPIWKRYESLLLEADCKKTLMKLERFEFYERAKKAFAVVATGEMALYGNIILKKGTLDLGPS",
    "output": "Involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSIGGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSEGRLVIKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIRLTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF",
    "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MYPAHLLVLLAVCVSLLGASDIPPQPLNLVQFSNMIQCANHGRRPTSNYMDYGCYCGKGGSGTPVDELDRCCKIHDDCYGEAEKSQKCAPYWTWYTWKCGSDGPQCDDSKTGCQRFVCDCDATAAKCFAKAPYNKENYNIKTRCQ",
    "output": "Snake venom phospholipase A2 (PLA2) that inhibits collagen-induced platelet aggregation. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MANNRVKSTNDLELKDRLVAINRVTKVTKGGRTFSFAAIVVVGNEDGIVGWGLGKAGEVTTAIAKGVEAAKKNLIKVPVHKGTIPHEQLAKFGGAQVLIRPASHGTGVKAGGAMRAVLESVGITDVLAKSKGSSNPHNLVKATIAALGELRSPFDVAQNRGVAVEKVFRG",
    "output": "With S4 and S12 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSEFSNVTVIKKANIYFEGKVASHTVLFPDGTKKTLGIMQAGDYEFSTANAEVMEILSGTLEWQMKGECCWKTIGAGESFQIPADSVFLMKVPAVADYCCSYIQ",
    "output": "Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEPLFPASPLTTWNTSSVVPSGSGDENGTLAGLGPSPGARAVVVPVLYLLVCAVGLGGNTLVIYVVLRHAKMKTVTNIYILNLAVADVLLMLGLPFVATQNAISYWPFGPVLCRLVMTLDGINQFTSIFCLTVMSVDRYLAVVHPIRSARWRRPRVAKLASAAVWAFSLVMSLPLVVFADIQEGWNTCNLSWPEPVGLWGAVFIIYTSVLGFFGPLLVICLCYLLIVVKLKASGVRVGSTRRRSERKVTRMVVVVVLVFAGCWLPFFIVNIVNLAFALPEEPASAGAYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKVLCLRKGYGAGAEDADATEPQPGPSSRLQEAMMPVRSCKANGLMQTSKL",
    "output": "Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEIAANWEGQAFSRFEEQFQQLSPKVEKFAQLLEEIKQQLNSTADAVQEQDQQLSNNFGLQ",
    "output": "Virulence factor that is important for the establishment of infection in the host. EsxA is required for EsxB synthesis as well as secretion (By similarity). Modulates host cell apoptotic pathways and mediates together with EsxB the release of S.aureus from the host cell. By acting on apoptosis, plays a role in the modulation of dendritic cell-mediated immunity (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPATQLVVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWATGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR",
    "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEAVRPDSCERGTAAARAEERPAPEARAHFRVTRFIMEAGVKLGMQSIPIATACTIYHKFFCEINLDAYDLYLVAMSSLYLAGKVEEQHLRTRDIINVSHRYFNPGSEPLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYLISLKNWLNRYSWQRTPISVTAWALLRDSYHGGLCLRFQAQHLAVAVLYLALQVYGVEVPAEGEAEKPWWQVFSDDLTKPIIDNIVSDLIQIYTMDTEIP",
    "output": "Activating cyclin for the cyclin-associated kinase CDK10."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVAIDLGASSGRVMLASYYPGQQQLTLREVCRFTNQIKSIDGSDVWDIDAIEQSIREGLSQLDSEGIALDSIGIDSWGVDFVLLDKQGKRIGQPVSYRDSRTQGVMARAQQTLGSNAIYRRTGIQFLPFNTLYQLRALSEQQPHLLADVAHLLLIPDYLHYRLTGQLNWEYTNASTTQLLNIETGDWDSDLLAYAGVPAHWFAKPGKPGNTIGYWHSANGQQVPVVAVATHDTASAVLAAPLIDADAAYLSSGTWSLMGFESGTPLTHQQAQCSNITNEGGAEGRYRVLKNIMGLWLLQRATDELQIDDLPQLIEQAARQPACRSLINPNDSRFINPPNMCREIQNACREHQFPVPNTAAQLARCIFDSLAMLYRQVAQELATLRGRPISHLHIVGGGCQNQFLNQLCADACGLNVSMGPVEASTLGNIGSQLISLGEVADVTHYRRIVANNFPLHHLSPHDNSDFAAHWLQFQSLSQLPKELCI",
    "output": "Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTSATKTNNSGSISSPIVVALDYANKDAALAFADQVSPQDCRLKVGKEMFTLYGPELIRDLHQRGFDVFLDLKFHDIPNTTARAVAAAAELGVWMVNVHASGGARMMSAAKEALLPYGAQAPLLIAVTVLTSMDGEDLRDIGITISPAEQAERLAKLTWDCGLDGVVCSAHEAVRLKQVCGEDFSLVTPGIRPQGSEAGDQRRIMTPEQAVAVGVDYMVIGRPITQSPDPEKTLREILASLTKVA",
    "output": "Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSGGTTKAAENAKADLPRLMKALRDQGVTDPQVLKAIETTPRDLFTPDLFKDRSWEDSALPIACGQTISQPYIVGLMTQALTVEPRSRVLEIGTGSGYQTTILSKVSRLVYTIERYRTLMKEAEARFNTLGLTNVITKFGDGGEGWAEQAPFDRIMVTAAAEDDPKRLLSQLKPNGVLVAPVGKGPVQSLRRYAGDGKGGFRVEILCDVRFVPLLAGVAKDQ",
    "output": "Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MWTKPKFEEMRLGFEVTLYISNR",
    "output": "Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPALSRWASLPGPSMREAAFMYSTAVAIFLVILVAALQGSAPRESPLPYHIPLDPEGSLELSWNVSYTQEAIHFQLLVRRLKAGVLFGMSDRGELENADLVVLWTDGDTAYFADAWSDQKGQIHLDPQQDYQLLQVQRTPEGLTLLFKRPFGTCDPKDYLIEDGTVHLVYGILEEPFRSLEAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQETTYWCYIKELPKGFSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTEDRELATVGGFGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFNNEDVCTCPQASVSQQFTSVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLPKVISTLEEPTPQCPTSQGRSPAGPTVVSIGGGKG",
    "output": "Conversion of dopamine to noradrenaline."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKFSLACLLALAGLQAALADPATCEKEAQFVKQELIGQPYTDAVANALQSNPIRVLHPGDMITMEYIASRLNIQVNENNEIISAHCA",
    "output": "Elastase inhibitor."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQLVVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWATGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR",
    "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTEYKKVIAQNNKAIFNYFIEERLEAGIVLNGSEVQSLRQGKASIEESHAADTGHEVFLYNCHIAEYEKANRFNHSTRRPRKLLLHTKEIKKIIGRIRIKGYTLVALSMYFNKQNKVKVELGIAKGKKLHDKRESIKEKDWKRDQSRLIRQK",
    "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSTQIAPARISDPAAFGRVAVLLGGTSSEREVSLNSGSNVLDALRARGVDAQPVDGIPALAQALVAQRFDRVFNVLHGHNGGGEDGIVQGLMEAFGVPYTGSNVLGSALSMDKIRTKQVWLSLGLSTPRYARLAAGASAQQIHAAAEQIGLPVIVKPANEGSSVGVSRVFDQAQLDEAVTLAARYDGALLMEQLIEGDELTVAVLGDVALPSIRIVPKGQWYDYNAKYIAEDTQYLCPGLDGDAEAQIGQLALDAFRAAGCSGWGRVDVMRDGSTGQLYLLEVNTAPGMTSHSLVPKAARQLGIDFEALVWRVLEQTL",
    "output": "Cell wall formation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFAEQDINDLKEISATLERVLNHPDETQARRLMTLEDIVSGYSNVLISLADSHGKTVYHSPGAPDIREFARDAIPDKDARGGEVFLLSGPTMMMPGHGHGHMEHSNWRMISLPVGPLVDGKPIYTLYIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSRQIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKKMLNLADEVGKVFDFFEALAEDRGVELQFVGDECQVAGDPLMLRRALSNLLSNALRYTPPGEAIVVRCQTVDHLVQVIVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSNARGTRFVIVLPERG",
    "output": "Member of the two-component regulatory system CusS/CusR involved in response to copper and silver. Acts as a copper/silver ion sensor. Activates CusR by phosphorylation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MADKEKDAVIVDETEHVDVDSKESKKEKKTKQQQKIEFLEAEVKELNDKYLRTLAEAENFKKRIQAEKIMDRKYAASSFATELLVPYEQFSKIVDFPSDNELLNNFLIGFKMIRDQFKSVLENEGVVEIKALGEVFDAKVHHAIEKESNKDKPNGTVLEVLQNGYLFKDRILRPAMVKINEWSEDNGEDK",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAATEDERPTGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAINYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSENVHIST",
    "output": "Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include RAC1, RAC2, RAP1A and RAP1B (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLQGSLVALITPMNQDGSIHYEQLRDLIDWHIENGTDGIVAVGTTGESATLSVEEHTAVIEAVVKHVAKRVPVIAGTGANNTVEAIALSQAAEKAGADYTLSVVPYYNKPSQEGMYRHFKAVAEAAAIPMILYNVPGRTVVSMNNETILRLAEIPNIVGVKEASGNIGSNIELINRAPEGFVVLSGDDHTALPFMLCGGHGVITVAANAAPKLFADMCRAALQGDIALARELNDRLIPIYDTMFCEPSPAAPKWAVSALGRCEPHVRLPLVPLTEGGQAKVRAALKASGQL",
    "output": "Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLERLSGHTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAFEVDNSGLAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNTDGKGHLVGHITDGTGAIRSLAEEGVAIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNRKTATFKQAKQVLKGINAKTSALASLQDLADDRAFRRSIAESSIYIDATGVGMKPLEEHSLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMTGEDMPVAYIRELLCRNKE",
    "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVMFKSYAYNLKFALENGMDVVALGNVSVYEKEGSYQLYVKDMKREGIGDLYVAFEKLKEKLKEEGLFDDAHKKEIPKFSKKIGVITSPTGAAIKDIINVTKRRNKGIELLIYPALVQGTDASKTLIEGIKTLNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDFTIIDFVSDRRAPTPSAAAEIAAFDREVLINEILNYKYNIKNSMENIIKEKRNYLNLYKQKIEANSPTNIIANEYRNIDNLKELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYTLIEDEGNNLITEKEALKELNKINIIFKDGRAKLSIKYIEEF",
    "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKAVVLVVVSLLALSSINCDVFFEEKFPDDSWESNWVYSEHPGKEFGKFKLTAGKFFSDPEDDKGLKTSEDARFYALSRKFKPFSNEGKPLVVQFTVKHEQDIDCGGGYLKVFDCKLEQKDMHGETPYEIMFGPDICGPGTKKVHVIFSYKGKNHLIKKDIRCKDDVYTHLYTLIVKPDNTYEVLIDNEKVESGDLEADWDFLPNKKIKDPEAKKPEDWDDKPTIPDPEDKKPEDWDKPEHIPDPDATKPEDWDDEMDGEWEPPMIDNPDYKGVWAPKQIDNPAYKGPWVHPEIDNPEYTPDSNLYKRDEICAVGLDLWQVKSGTIFDDFLITDDPAAAKERGEVIKKRQEGEKKMKSEQDEAEREKEKAEKPDDEEDDEDLDDETGDAAPVEEHDEL",
    "output": "Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRMVDIIEKKRDGKSLSKEEIEFFIKGYTNGDIPDYQASSLAMAIFFQDMNDEERAALTMAMVNSGDVIDLSKINGIKVDKHSTGGVGDTTTLVLAPLVAAVGVPVAKMSGRGLGHTGGTIDKLESIKGFHVEISEEDFIKLVNENQVAVIGQSGNLTPADKKLYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGNGAFMKTLEDAEALAHAMVSIGNNVGRNTMAIISDMSQPLGRAIGNALELKEAIDTLNGKGPEDLTELVLTLGSQMVVLANRANTLEEARQLLNEAIENGSALEKFKTFLENQGGDVSVVDAPELLPTATYQIEYKAQSSGVVSELIANEIGVASMMLGAGRQTKEDEIDLSVGIVLNKKVGDVVKEGESLLTIHSNRENVDDVIKKLDESIEIQAQATTPTLIHKIITE",
    "output": "Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTVYHFVGIKGTGMSSLAQILHDMKHTVQGSDYEKRFFTQTALEKRSISILPFDKNNVEEGQVIIAGNAFPDTHEEIVAAKELNIPVHRYHHFLGDLMSQYTSVAVTGAHGKTSTTGLLAHVMQGAHPTSYLIGDGTGHGVENSKYFVFEACEYRRHFLSYNPDYAIMTNIDFDHPDYFADINDVFSAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDGTIFDVFVRNTYYDTFKITGYGNHSVLNALAVIALCHYENVDVEAVKHQLTTFEGVKRRFNEKPMGEQVIIDDYAHHPTEINATIEAARQKHPEREVVAVFQPHTFSRTEKFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTTDVLKKHKNGVLIFMGAGDIQKFEAAYVKEVQVAEK",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MADSYLHAPTLVRATTPLVQCLTNAVVMQFTANALLAIGASPAMVDTPAESFDFAGVADGVLINAGTPSAEQYAGMERAIEGATAAGTPWVLDPVGVGGLAERSAFLRRAVDKHPAAIRGNASEIVALAGLGAGGRGVDATDDVADAVEAAQVLARRTGGVVAVTGAEDLIVSRGRVSWLKSGDPMLQLVIGTGCALGAVTAAYLGATQDTDIDPHDAVVAAHAHLGAAGRIAATRATAPGSYAVALIDALHQLDRNQLANLTHLREENR",
    "output": "Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFKNLCDKIMTQKILITSALPYANGPLHFGHIAGAYLPADCYARFQRLMKKDVLYICGSDEYGIAITLSADLAGRTPQEHVDLFHHINQSFFEQLQISFDHYSRTTWKGHVEPTHQFFNDLLQNGYIEERTTDQLYSEKDQKFLADRYVVGTCPRCGFENARGDECPCCGASYEATELKNPRSKLTDASLILRPTKHWFLLLEKFKKPLMEWLETKNWKPNVINFIRGYIDHLHARAITRDMKWGISVPLPDSEGKVLYVWFDAPIGYISATKEWALLRGEEKLWEKYWLDPETKLVNFIGKDNIPFHASIFPAMIMGQNQPYKLVDELPANEFYNLEGKQFSKSDGWYIDLEDFFKHYTSDQIRYAIASNAPETSDSEFTWKDFQLRCNSDLLGKYGNLVNRVLVFIHNQCQGKVPESGVLEEQDRKFLKNIQDLVDQAAASYSTFKVRKASQIMMELSQLGNVYFDSKKPWQDAKNDYTKGRMHTTLNCCMECLKALALISFPIIPTAASKVWQFLGFQTPLEQEDWNRVKIEKLPLNQKILTPQILFQRVENEAVEREILKLQQLSLTKEKKSTPQSTQISISENILLKPLVDIEDFRKLDLRVGKIIQANPVPKSKKLFQLLVDIGIEKRIVVAGVAEFYKVEDLIGKNVVVVANLKPANLMGVTSQGMLLAAKGEGNLKLISIEDVAPGSLVS",
    "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNRIALGLHYDGAAFSGWQSQPHRNTVQDHLEDAIERFAGVRLLTTVAGRTDAGVHALGQVIHLDTELVREPFSWVRGVNAFLPPSIALQWALPVDVGFHARFLAYERMYYYALYTGPHRVPMVHGRAGYQMLPPGQRLDVEAMRAAAAHLIGEHDFSAFRAAECQAKSPVKTMYDVTIRDDGNWVFLRFRASAFLHHMVRNLMGCLVAVGRRRYPPDWMAQVLAGRDRKLAAPTFMPDGLYLVGVKYPDAYPIPAADPSASLFHGVFDDAA",
    "output": "Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MACLLETPIRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTDATVIPHLMALLSRSRYTQEYICQIFSHCCKGPDHQTILFNHGAVQNIAHLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDKAKMALQQYLA",
    "output": "Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSDPDRARVLAAAGVSRETAERLDLYVAQLRRWQPIKNLVGPATLTEVWSRHIDDALQLLDLAPEARTWLDLGSGAGIPGLILAIAGRERGVRVDLVESNARKCAFLTETARLTEAPARVRNARIEAVIGEYGGTDVVCARALAPMTQLLAWTEPLLKTGTTGLFPKGRDVQAELTQAGAQWRVVNDLVPSRTDSEARIVRVTALAAPSHR",
    "output": "Specifically methylates the N7 position of guanine in position 527 of 16S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MASLKDMRVRIASTKATQKITKAMQMVAASKLRRAQMAAEAARPYAEKMDSVISNIAGAAAGSPGAPVLLAGTGKDQVHLLLVCTGERGLSGAFNSSIVRLARERAYALMNQGKEVKFFCVGRKGYEQLRRTFDKQIIENLELRSVRQLGFVNAEDIAKKVIARFNAGEFDVCTLFYSRFKSVISQIPTAQQLIPLVVEAPAAGSVATSYEYEPEEDEILSTLLPRNLAVQIFRALLENNASFYGAQMSAMDNATRNAGDMIRKQTLIYNRTRQAMITKELIEIISGAEAI",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNRLGFVFQSAPHSTSKGREGLDAILAASAYSEDIQIFFIGDGVLQLLKNQEPEKILSRDYISGFKMLELYDLEEIFVCQNAMGNRGIKEEYLLIDVDSISNKDINEKLSQCDQIMVF",
    "output": "Could be part of a sulfur-relay system."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEYRKIKDEDDHDVASDIESVKGKSHTVASSNIAMATLGVGSSERINWKRKGVVTCALTILTSSQAILIVWSKRAGKYEYSVTTANFLVGTLKCALSLLALTRIWKNEGVTDDNRLSTTFDEVKVFPIPAALYLFKNLLQYYIFAYVDAPGYQILKNLNIISTGVLYRIILKRKLSEIQWAGFILLCCGCTTAQLNSNSDRVLQTSLPGWTMAIVMALLSGFAGVYTEAIIKKRPSRNINVQNFWLYVFGMAFNAVAIVIQDFDAVANKGFFHGYSFITLLMILNHALSGIAVSMVMKYADNIVKVYSTSVAMLLTAVVSVFLFNFHLSLAFFLGSTVVSVSVYLHSAGKLR",
    "output": "Sugar transporter involved in the transport of CMP-sialic acid from the cytoplasm into the Golgi (By similarity). Essential protein."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQVCAKTTGHTEAVEIIFDPEEISYKELVELYWVQTDPTDAFGQFEDRGDNYRPVIYYTTERQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIRHQFLEENWS",
    "output": "Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDKFTTHTGVGIPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAAWRNDPSFVLNNEGYAGASVLVAGPDFGTGSSREHAVWALQNYGFKVVISPRFADIFRGNSGKAGLLAAQVDESVVQKIWDLLDEHPGTAVTVDLESRTVRAGEGVDAIEASFDIDDYTRWRLLEGLDDIGITLGHADAIASYEATRPSWRPATIHAH",
    "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVLTSKQKEELNGSILDYFESSQYKSSFEEFKKETGTELDVKKKGLLEKKWTSVIRLQKKVLDLEAKVAQLEEELNSGGGRGGGRGRGKEDALPRPPEKHILTGHRNCINSVKFHPSFSLMVSASEDATIKVWDFESGEFERTLKGHTNAVQDIDFDKTGNLLASCSADLTIKLWDFQTYDCVKTLHGHDHNVSCVRFTPSGDQLISSSRDKTIKVWEAATGYCIKTLVGHEDWVRKITVSEDGSCIASCSNDQTIKTWNIVKGECLATYREHSHVVECLAFSTANIIDIPGSLLSTPEGKSKVKQGPGGNLVGQCGYLATGSRDKTIKIWELATGRCLATYIGHDNWVRAVRFHPCGKFLLSVGDDKTIRVWDIAQGRCIKTINEAHTHFISCLDFCLHNPHIATGGVDDVIKVWKLQ",
    "output": "Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the coupling of the nucleus and centrosome and dynein/dynactin-mediated interactions of microtubule tips with the cell cortex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAEITVTIDTDQQKQAISDSFAKLDPQYLVKNPVLFVVELGTIIGLVMTIAPGLFGATGSRVYYAVITVLLGFTVIFANYAEAYAELEGEAQADSLRALQTEAEGKLLQNDDVDIEDISEDDYEVVASTEIEQDAVVFVDEGDIIPRDGTVVEGSASVDESAITGESEPVIRQSGGDRTSVVGGTEVLSDRIKVEVTSEEGESFLDQMIGLVEDAQRQKTPNEIAMTILLSGLTLVFVVAVATMFFFGEYLASFVGGFAGLDVAELVALLVALMPTTIGALLAAIRVAGMTRVTRRNVIAKSGRAVEAAGDLDALILDKTGTITTGERVAQDFHPLGDADDADVVRASYQSSLYDETTEGRSIVKLAEKMNGKVQTDGGQSASEELDEPGDSVDAPRDVSVTLDAEGLSESNFVPFSAETRMSGIDLSDGTEIRKGAVDAVEEYATTVPGKLRQKSNAISESGGTPLAIAVDGQVVGIIELQDELKPGIADRIAEIQKMGVETIMATGDNQRTARWVADQVGIDEFHAEFDPEEKIELVEDIQDDGKLVGMTGDGTNDAPALAKADVGLAMNAGTNAAKEAGNMVDLDSNPSKIIEVVGIGKQLLMTRGSLTTFSVANDVAKYFVLLPAILAAAIPGLGAMDILNLSTPASAVTATLMYNAFIIPLLIPLALRGVDYKAQSGAQLLRKNLIVYGGGGLIAPFIFIKAIDMLFVALGVFQ",
    "output": "Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSEQPTEPLSIKEEYQLWRKNCRYMYEFVSETALMWPSLTIQWLPNYTTTNGLIDAKLLLGTHTSNQSANQLKVASTQLSADPNVKANSKIKTVQKLENNAEICRARYMPQDANIVATINGLGEVDLYNLDTETRYSHFAPHTKNGYGLSWNPKQKGLLVTGADDNFVCVTDTTTNKTTFKSDIQKDIVNDVKWHQFNGNLFASVSEDSHVYLFDARDNKVVSQYYAESSNGINSLAFSPFAENLVAIGNTSSNINLLDLRKLGENSGLLHTMMGHSEGITCMEFSPHHDGILATGSQDRRIIIWDLFKVGEEQQQEDAEDGCPELFMMHAGHTAGVSDLSWCPFKDWMIGSVADDNIVHLWEISKKLITNEEAEVDVSILE",
    "output": "Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-14' of histone H4 which is required for telomeric silencing."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MASPEGTDGEGMGCCGWFQVEAIVERKTGDTISDDESEEENETDTDVDGFIDNTLINNTQEDRETAQQLLQVQTAHADAQTLQKLKRKYIGSPLSDISNQQTVYREEVKRRLILSEDSGYGNTLETLETSQQVEYEKGNGCGSSQNGGSQNSNCSEHSVSNMDIDTNMETPTHQLQELFKSSNVQGRLHFKFKEVYGVPYTELVRTFKSDSTCCNDWICAIFGVNETLAEALKTILKPQCVYYHMQCLTCSWGVIVMMLIRYICGKNRKTITKSLSSILNVPQEQMLIQPPKLRSPAVALYFYKTAMSNISEVYGETPEWIQRQTQLQHSLQDNQFELSKMVQWAFDNEVTDDSQIAFLYAQLADIDSNAQAFLKSNMQAKYVKDCGIMCRHYKRAQQQQMNMCQWIKHICSKVDEGGDWKPIVQFLRYQGVDFISFLSYFKLFLQGTPKHNCLVLCGPPNTGKSCFAMSLINFFQGSVISFVNSQSHFWLQPLDNAKLGLLDDATDTCWRYIDDYLRNLLDGNPISLDRKHKQLVQIKCPPVIITTNVNPMQDAKLRYLHSRISVFKFENPFPLDNNGNPVYELSNVNWKCFFERTWSRLNLDNDEDKENNGDSIPTFRCVPEQNTRLL",
    "output": "ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins. During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity. Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer. Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori. Subsequently, two hexamers will be created. The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTATASDDEAVTALALSAAKGNGRALEAFIKATQQDVWRFVAYLSDVGSADDLTQETFLRAIGAIPRFSARSSARTWLLAIARHVVADHIRHVRSRPRTTRGARPEHLIDGDRHARGFEDLVEVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVARARDALLADAEPDDLTG",
    "output": "Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are usually held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; this sigma factor does not seem to have a cognate anti-sigma factor however. It has been suggested that the sigma domains 2 and 4 may interact via polar residues in this protein to autoregulate. Positively regulates expression of a small regulon of genes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVLSDKKFVLVTGGSSGLGFETIKALIQTNQPYHVFLGCLFPDEGQSAVLSLQRDVPETPSTLESILVDVTDDESIDRCFHTVQSKIGHLDVLVNNAGISLQASEIGMREAWNRCYDVNVTGAQIMTHTFVPLLLRSNDPRLIFITSGLSSLTPMSNVYTPTRMTVPAGWPKPEVHPYRAYRATKTALNMVMLEWHWQLREDGVKTWGVSPGFLATNLGASFAGMDGAPPVLPASVGGRLVASVVEGDRDTDVGKIVLKDGEVQPF",
    "output": "Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of the tropolone class of fungal maleic anhydrides . The pathway begins with the synthesis of 3-methylorcinaldehyde by the non-reducing polyketide synthase (PKS) tropA . 3-methylorcinaldehyde is the substrate for the FAD-dependent monooxygenase tropB to yield a dearomatized hydroxycyclohexadione . The 2-oxoglutarate-dependent dioxygenase tropC then performs the oxidative ring expansion to provide the first tropolone metabolite stipitaldehyde . Trop D converts stipitaldehyde into stipitacetal which is in turn converted to stipitalide by the short-chain dehydrogenase/reductase tropE . The next steps involve tropF, tropG, tropH, tropI and tropJ to form successive tropolone maleic anhydrides including stipitaldehydic, stipitatonic and stipitatic acids ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MILEHVLVLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNINFVTFSDFFDNRQLKGDIFSIFVIAIAAAEAAIGLAIVSSIYRNRKSTRINQSNLLNN",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSAAVVTVRGLRRAFGAQQVLDALDLDIADGEFVAMLGLSGSGKSTLLRILAGLDHQADGSVVVPRSRAVVFQNPRLLPWRRALANVTFALADAGPDAPSRTARGRAALDEVGLADKADAWPLSLSGGEAQRVSLARALVREPDLLLLDEPFGALDALTRLKMYRLLHDLWARRHMAVLHVTHDVDEAILLADRVVVLSDGRVSLDRRVDLPFPRSRGDEGFDDLRRVLLAELGVREEVGHDRGR",
    "output": "Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAFDVVGAGLDRLNQ",
    "output": "May regulate a gene cluster involved in mycofactocin expression. Mycofactocin is a conserved polypeptide that might serve as an electron carrier (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGFHQIDERNQALLSKIALDDGHGENSPYFDGWKAYDNDPFHPENNPLGVIQMGLAENQLSFDMIVDWIRKHPEASICTPEGLERFKSIANFQDYHGLPEFRNAIANFMGKVRGGRVKFDPSRIVMGGGATGASETVIFCLADPGDAFLVPSPYYAGFDRDLKWRTRAQIIRVHCNGSNNFQVTKAALEIAYKKAQEANMKVKGVIITNPSNPLGTTYDRDTLKTLVTFVNQHDIHLICDEIYSATVFKAPTFTSIAEIVEQMEHCKKELIHILYSLSKDMGLPGFRVGIIYSYNDVVVRRARQMSSFGLVSSQTQHLLAAMLSDEDFVDKFLAENSKRVGERHARFTKELDKMGITCLNSNAGVFVWMDLRRLLKDQTFKAEMELWRVIINEVKLNVSPGSSFHVTEPGWFRVCFANMDDNTVDVALNRIHSFVENIDKKEDNTVAMPSKTRHRDNKLRLSFSFSGRRYDEGNVLNSPHTMSPHSPLVIAKN",
    "output": "Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ",
    "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNIYMTDEGKLLTEEQLKLVEAILVYTATEEKIEANSELSVTFVTNDEIQQINREWRGKDQATDVISFAMDELGEDEIDFELLEDEPVVLGDLIISVERCREQAAEYGNHFERELGFLAVHGFLHLLGYDHIEKADEDIMTKRQEEILHHFELYRGKL",
    "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRDPVSSQYSSFLFWRMPIPELDLSELEGLGLSDTSTYKIQDSSAAKMTGKAPGAEQEKNPEGDALLEYSTFNFWRAPIASIHSFELDLL",
    "output": "Cofactor for the transcription factor TCF7. Involved in regulation of lymphoid development by driving multipotent hematopoietic progenitor cells towards a T-cell fate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTYLLALDQGTSSSRSIVFDELGHIVAQAQQELPQIYPKPGWVEHDPMEIWRTQLATAREALGKAGLKASDIRALGITNQRETTVVWHRATGQPIHNAIVWQDRRAEATCAQLREQGKEALIQSKTGLLIDAYFSGTKLKWLLDNVPGVRAQAERGELAFGTIDSWLMWQLTGGALHATDVSNASRTMLFNVRTNQWDAELLDLLGIPASLMPQVLPSSAHYGETRPELLGHAIAIGGVAGDQQSALFGQACFKAGMAKNTYGTGCFMLMHTGTQFQTSHNGLLTTSAAQTTAHPEFAMEGSVFVGGAVVQWLRDGLHAIQGSGEVQALAQSVPDSGGVMMVPAFTGLGAPYWKPDARGTITGLTRGTTVAHIARAALESIAYQSAALLQAMSRDAVSSGAAPLAELRVDGGACANDLLMQFQADLLGIPVLRPAVIETTALGAAYLAGLSSGVYRSTDELSGMWRAERTFLPTLGADSAAALMNRWEHAVRQTVLP",
    "output": "Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTKLFTPLHVGRMELANRIAMAPMTRYRASDNHVPLPIMKDYYAQRASVPGTLLITEATTISARAGGYANAPGIYNDAQIAAWKEVTDAVHAKGSYIYVQLWAVGRPANPQLLQAEGGYDLVSSSATAVSADAPTPRALSETEIYAWIADYAQAARNAVAAGFDGVEIHAANGYLIDQFTQDICNTRTDAWGGSVQGRARFALEVSRAVVEAVGADRTGIRFSPWSTFQGMRMKDPKPQFEYLAVQTAKLGLAYVHLVESRIAGGADVDATDRLDFFLRAYGKASPVIFAGGYDAESAVRAVDVEYADYDAIVGIGRPFISNPDLPFRVQNGIPFVPYDRATFYVPKDPKGYTDYAFSAEFQKAIEAAA",
    "output": "Chanoclavine-I aldehyde reductase; part of the gene cluster that mediates the biosynthesis of isofumigaclavines, fungal ergot alkaloids . The tryptophan dimethylallyltransferase ifgA catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan . The second step is catalyzed by the methyltransferase ifgB that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of N-methyl-dimethylallyl-L-tryptophan . The catalase ifgD and the FAD-dependent oxidoreductase ifgC then transform N-methyl-dimethylallyl-L-tryptophan to chanoclavine-I which is further oxidized by ifgE in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde . The chanoclavine-I aldehyde reductases ifgG and/or fgaOx3 reduce chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6,8-dimethyl-6,7-didehydroergoline . The festuclavine dehydrogenases ifgF1 and/or ifgF2 then catalyze the reduction of 6,8-dimethyl-6,7-didehydroergoline to form festuclavine . Hydrolysis of festuclavine by a yet undetermined cytochrome P450 monooxygenase (called ifgH) then leads to the formation of isofumigaclavine B which is in turn acetylated by ifgI to isofumigaclavine A . Penicillium roqueforti has interestingly at least two sets of genes for the consumption of chanoclavine-I aldehyde on three different loci, the OYEs ifgG/fgaOx3 and the festuclavine synthase homologs ifgF1/ifgF2 . The reason for the duplication of these genes is unclear, probably to ensure the conversion of chanoclavine-I aldehyde by differential gene expression under various environmental conditions ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQKKDILFSIGWPLSSLYAGIMKLRCLLYRRGLFRQHHFPVPVISVGNLTMGGTGKTPVTHYIAKLLLEHGLQPAIISRGYSGKSGGEVNIVSDGQRILLSAEQAGDEPYMLASMLAGVIVITGKKRYLSCKYAVEKMQAEVIILDDGFQHLAVARNLDLVLFDAQTGMGNNRVFPGGDLREARFALDRADAFLITGKCPREEEELLAIELELQHELPQCPLFSVYRTEGVFYSAKQEKVVTHLPKKVFAFCGIANPERFHHDLEKQGFSLVGFKAFSDHQQYTGQCIEEIVKEAKKGGAQAIITTDKDLVKIDSFATELPLYSARPRTTISTDFDELILKTCASFGE",
    "output": "Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPVGVPKVPFRSPGEEDATWVDIYNRLHRERLLFLGQEVEGEISNQIVGLMVYLSIEDDTRDLYLFINSPGGWVIPGIAIYDAMQFVPPDVHTICMGLAASMGSFVLAGGEITKRLAFPHARVMIHQPASSFYEAPAGEFILEAGELLKLRETITSVYVQRTGNPLWVVSEDMERDVFMSATEAQAHGIVDLIAVENTWDFP",
    "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MADSKEIKRVLLSPLFDNNPIALQILGVCSALAVTTKLETALVMTLAVTLVTAFSSFFISLIRNHIPNSVRIIVQMVIIASLVIVVDQVLRAYAYEISKQLSVFVGLIITNCIVMGRAEAYAMKSPPIESFMDGIGNGLGYGVILVLVGFVRELVGSGKLFGVTVLETVQNGGWYLPNGLFLLAPSAFFIIGLLIWGLRTLKPAQIEKE",
    "output": "NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MALKRIHKELNDLAQDPPAQCSAGPVGEDMFHWQATIMGPNDSPYQGGAFFLTIDFPTEYPFKPPKVEFTTRIYHPNVNSNGSICLDILRSQWSPALTISKVLLSISSLLCDPNPDDPLVPEIAQIYKTDRDKYNRTAREWTQKYAM",
    "output": "Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by RIGI in response to viral infection Plays a role in early maturation of the testis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKVFYDKDCDLSLVKGKTVAIIGYGSQGHAHALNLHDSGVKVVVGLRKGGASWNKAANAGLEVAEVAEAVKRADIVMMLLPDENIAAVYRDEVHANIKAGAALAFAHGFNVHYGQVVPREDIDVIMAAPKAPGHTVRSTYSQGGGVPHLIAVYQDKSGSARDVALSYASANGGGRAGIIETNFREETETDLFGEQAVLCGGTVELIKAGFDTLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEFGEYETGPKVVTDATRQAMRECLTAIQTGEYAKKFILENAAGAPTLTSRRRINAESQIEQVGGKLRAMMPWIAANKLVDKAKN",
    "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFGHFKLVYPAPISEPIQSRDSNAYMMETLRNSGLNLKNDFGIGRKIWRVFSFTYNMVILPVSFPINYVIHLAEFPPELLLQSLQLCLNTWCFALKFFTLIVYTHRLELANKHFDELDKYCVKPAEKRKVRDMVATITRLYLTFVVVYVLYATSTLLDGLLHHRVPYNTYYPFINWRVDRTQMYIQSFLEYFTVGYAIYVATATDSYPVIYVAALRTHILLLKDRIIYLGDPSNEGSSDPSYMFKSLVDCIKAHRTMLNFCDAIQPIISGTIFAQFIICGSILGIIMINMVLFADQSTRFGIVIYVMAVLLQTFPLCFYCNAIVDDCKELAHALFHSAWWVQDKRYQRTVIQFLQKLQQPMTFTAMNIFNINLATNINVAKFAFTVYAIASGMNLDQKLSIKE",
    "output": "Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSGLILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGTMDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVAAQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS",
    "output": "Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTTPHSIAESTDPEVFPANNRHLTVSYASRYPEYTRIPAITLKGQWLEDAGFTTGTQVDVRVMNGCIVLTAQQPQPEESELMQSLRQVSKLSARKQKQVQAFIDVMAGSK",
    "output": "Involved in the degradation and recycling of damaged RNA. It is itself a target for degradation by the ATP-dependent protease Lon."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRDLKTYLSVAPVLSTLWFGSLAGLLIEINRLFPDALTFPFF",
    "output": "May help in the organization of the PsaE and PsaF subunits."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSFSCPLCHQPLSREKNSYICPQRHQFDMAKEGYVNLLPVQHKRSRDPGDSAEMMQARRAFLDAGHYQPLRDAIVAQLRERLDDKATAVLDIGCGEGYYTHAFADALPEITTFGLDVSKVAIKAAAKRYPQVTFCVASSHRLPFSDTSMDAIIRIYAPCKAEELARVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPHAEQLEGFTLQQSAELCYPMRLRGDEAVALLQMTPFAWRAKPEVWQTLAAKEVFDCQTDFNIHLWQRSY",
    "output": "Specifically methylates the guanosine in position 745 of 23S rRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSPQTETKTSVGFKAGVKDYKLTYYTPYYETKATDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIERVFGEKDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYTKTFKGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMLRRAYFAKELGVPIIMHDYLTGGFTANTSLAHFCRENGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDNFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTDIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGLDLAQDGNSIIRQASNWSPELAAACEVWKEIQFNFKSVDTLDLNEIK",
    "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEMLYGIMPEISLLLSALIFQLIGAYSNNTLTHVIAKMAIGFAAILIAILVFHPSWFNGIYWNNTFIVNQSKIYLKIIILIFYIFLTLIYSGYIKVANLKGHSEYIVLMQLGALGGLILVSANDFMVMYLGIEMQGIIGYILTTFNYNNSRSSEAGLKYFILGTVFSAIMLFGISLVYGTTQSIRYDIALHALQNPSSDMAVLVAAILMILVGVLFKLSIAPFHMWTPDIYDGAPLVVVALFSSLPKISVLALLGNLLSELKFASDAFFYIKTIIMVLACLSLIVGAFGALLQQSIQRFIAYSAILNLGYAVLALVANSSNVIRAEISYFYIIIYAASMLGFIAIIINNFTNRANYLKISHLSGLSNVKKLSSILIAIQMFSLVGIPPFAGFISKYIIFTSILKSGMYELIIMGIAAVVIGSYCYLNIVKVMYFLPATVRFQNSSVNFELSLVSIASTIIVISLMIICMLFGEGLNVIV",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MADATHAAADGGVATILASADGRDFLLRNSADKVKISSIKASTVALYFSASWCPPCRRFTPKLIEAYNELVSQGKSFEVVFVSGDSDQDAFNAYFAKMPWLAVPFSDSEALAKLNERYKVMGIPHLVILDAKSGEIYTEDGVELVHEYGTEAYPFTTERINELKEQEKAAKDNQTIHSLFGTPTRDYLITNKGDKVPISDLEGKYVGLCFVVNGYGPVVQFTSVLAKIYEKLKAVGEKFEVVMVSLDGDEESFNESFADMPWLAIPQGDKMCEKLARYFELSGLPMLVLIGPDGKTLNDDIADIIDEHGPDAWEGFPFSAEKLEILAEKAKAKAESQTLESLLVTGDLDFVLGKDGAKVPVSELVGKTVLLYFSAKWCPPCRAFLPKLVNEYNKIKEKHNDFEIVFISSDREQSSYDEFFSGMPWLALPLGDERKQQLSKIFKITGIPSLVAIGPDGKTVTKDAKTPLVAHGADAFPFTEEKLQELEKEKEKKINDMAKGWPEKLKHDLHDHELVLTRCTTYGCDGCDEMGDSWSYRCKECDFDLHPKCALEEKGDVEMGEENAEAAPAGYVCEGDVCRKV",
    "output": "Probable thiol-disulfide oxidoreductase that may participate in various redox reactions."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "QLTFTPGW",
    "output": "This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPTIQQLIRHGRSMKASKTASPALEKCPQKRGVCTRVYTTTPKKPNSALRKVARVRLSNKIEVTAYIPGEGHNLQEHSIVLIRGGRVKDLPGVRYHIVRGSLDTSGVADRKQSRSKYGAKQPKAGAAKK",
    "output": "With S4 and S5 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAGAAALRRSARRVVLPGAYALSRALQHPERLLSSQASPDRGGVLGSELGLYPPERVRNFSIIAHVDHGKSTLADRLLELTGTIKKGHGQPQYLDKLQVERERGITVKAQTATMFYRHANNQLPASDQPDAPSYLLNLIDTPGHVDFSYEVSRSLAACQGALLVVDAAQGVQAQTIANFYLAFESNLSIIPVINKIDQPTADPDNVKAQLKRLFDIDPSEALLTSAKTGQGLSQVLPAVIERIPSPPGKCDSPVRMLLLDSYYDEYKGVICHVAVVDGALHKGDKIASAATGRTYEVLDVGIMHPELTPTGVLYTGQVGYVISGMRSTKEARIGDTLHQAKSIVEPLPGFKPARHMVFSGLYPADGSDFDALSHAIEKLTCNDASVSVTKETSTALGMGFRCGFLGLLHMDVFHQRLEQEHGAQVISTIPTVPYIFEYGDGSKVQVENPAALASNPGKRIAACWEPTVIATIIIPSEYVGPVIMLCSERRGEQQEYTFIDAQRALLKYRLPLREIIVDFYNELKSITSGYATFDYEDSEYQQSDLVKMDILLNGQPVDAMATIVHNQKAQRVGRELVDKLKKFIERQMFEITIQAAVGSKVIARETLSAMRKNVLAKCYGGDITRKKKLLEKQKEGKKRMKRVGSVDIPQEAFHELLKVSNSK",
    "output": "Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMRSHYCGQLNETLEGQEITLCGWVHRRRDHGGVIFLDIRDRDGLAQVVFDPDRAESFAAADRVRSEYVVKITGKVRLRPAGAVNKNMASGGIEVLGYELEVLNESETPPFPLNEYSDVGEETRLRYRFLDLRRPEMAEKLRLRSRMTTSIRRFLDENGFLDVETPILTRATPEGARDYLVPSRTHAGSFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQIDIETSFLDEKEIMGLTEQMIRNLFKEVLDLEFGDFPHMTFEEAMRRYGSDKPDLRNPLELVDVADQLKDVDFKVFSGPANDPKCRIAALRVPGGASMPRKQIDDYTKFVGIYGAKGLAYIKVNERANGVDGLQSPIVKNIPLDNLNAILDRVGAVDGDIVFFGADKAKIVSEALGALRIKLGHDLNLLTCEWAPMWVVDFPMFEENDDGSFSALHHPFTAPKCSPAELEANPAGALSRAYDMVLNGTELGGGSIRIHRKEMQQAVFRLLGINEAEQEEKFGFLLDALKYGAPPHGGLAFGLDRLVMLMTGAQSIREVIAFPKTQSAADVMTQAPGVVDAKALRELHIRLRETPKAE",
    "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAPGAPSSSPSPILAALLFSSLVLSPALAIVVYTDREIYGAVGSQVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGAFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGILGVVLLLLLLFYLIRYCWLRRQAALQRRLSAMEKGRFHKSSKDSSKRGRQTPVLYAMLDHSRSTKAASEKKSKGLGESRKDKK",
    "output": "Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAPGSTMWLLGYIFLCFPVSFALIKQPKPETPTDPGVLHCRPWNFKFTINFQNQETGSSPVLVTWDNQGRLHRLQNDTDCGTRVGEGPGPSVVLEANYSSCYVTESEPYYVMLVGVEEVDAAGQNLVTKQQLLKCPMHLPAPDAGLCDSVPVQDRLPCATAPISQEDCEELGCCHSSEEVNACYYGNTVTSHCTQEGHFSIAVSRNVSSPPLHLDSVHLVFGNDSECQPVVATRAFVLFLFPFTACGTTRQITGDRAIYENELLATREVRTWSRGSITRDSIFRLRVSCSYSISSSALPVDMHVLTLPPPLPETQPGPLTVVLQIAKDKDYHSYYTMDDYPVVKLLRDPIYVDVSILYRTDPYLGLRLHQCWATPRTNPLYQPQWPILVKGCPYTGDNYQTQLIPVQEAFDLPFPSHHQRFSISTFSFLDSSVAKEALKGPIYLHCSVSVCQPTGTQSCTVTCPIDSRRRNSDINFQNSTANISSKGPMILLQATEDPSEKLHKHSGVPVHPGALWVAGLSGIFIIGALLVSYVAIRTRR",
    "output": "Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDFKRLTAFFAIALVIMIGWEKMFPTPKPVPAPQQAAQQQAVTASAEAALAPATPITVTTDTVQAVIDEKSGDLRRLTLLKYKATGDENKPFILFGDGKEYTYVAQSELLDAQGNNILKGIGFSAPKKQYSLEGDKVEVRLSAPETRGLKIDKVYTFTKGSYLVNVRFDIANGSGQTANLSADYRIVRDHSEPEGQGYFTHSYVGPVVYTPEGNFQKVSFSDLDDDAKSGKSEAEYIRKTPTGWLGMIEHHFMSTWILQPKGRQSVCAAGECNIDIKRRNDKLYSTSVSVPLAAIQNGAKAEASINLYAGPQTTSVIANIADNLQLAKDYGKVHWFASPLFWLLNQLHNIIGNWGWAIIVLTIIVKAVLYPLTNASYRSMAKMRAAAPKLQAIKEKYGDDRMAQQQAMMQLYTDEKINPLGGCLPMLLQIPVFIGLYWALFASVELRQAPWLGWITDLSRADPYYILPIIMAATMFAQTYLNPPPTDPMQAKMMKIMPLVFSVMFFFFPAGLVLYWVVNNLLTIAQQWHINRSIEKQRAQGEVVS",
    "output": "Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEYVPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDDDEGDDEEWKPTKLVKVSRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCCCDPTKCRNRQQGKDSLGTVERTQDSEGSFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDVEQVLSKKTPPAPSPFDLPELKHVATEYQENKAPGKKKKRALASNTSFFSGCSPIEEEAH",
    "output": "Iron-sulfur (Fe-S) cluster binding motor protein that has a role in chromosome segregation during mitosis . Translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis . May play a role in mitotic chromosomal positioning and bipolar spindle stabilization (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRILLTNDDGIFAPGLEALRNALSDLAETIYIIAPDRERSATGHSITVHRPIRVREACHADGNCCGWIVDGTPADCVKLALESLLPETPDLVISGINLGPNLGTDVLYSGTVSAAMEGLINGVPSLAISLASHREAEFEEAAAFARRLLPLVFEYREIFTANTLLNINVPPGKPVGVRLTRLGNLRYADAVDRRVDPRGRYYYWMAGKPFSPDGHDPDTDIGAVKDRHISITPVKIDLTDYEALDALKKWPVDWKGS",
    "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPHNFRPGDLVFAKMKGYPHWPARIEDVADGAVKPPPNKIPIFFFGTHETAFLAPKDLFAYEKNQERFGKPNKRKGFNEGLWEIQNNPHASYNTPAAASSSDSEDNQPAAASDAEEEEEAVVPRKAETGSDDSDSGSEDQKKPAVKRKAPALKRPPVKKARASSSDRDGEESGSPSEPEPSPSSDSDSGKNSDQDFTPQKESGGRGGKKPAGRGRRKKASSGSDSDSGSQSDQKAARSDSEDEKPRPAASGSESQSGSKSDSDSEPPPPPPPTRKAPQGRKKAEKPPPKPRARKPKPAPERAPSSSSDSDSDSDTDRVSEWKKRDEERRKELEERRKREEAEELRRLREREKEEEEKRKKDKETKVRRGSSSSGSSSSDDEVDDHPLKKSKKPPPPPIPAPSDSDSPPPSELKKKKESQKGRQKKEKEVKEKKERPVKEKKPQRSEEKHKAKPKAEKPKRKPVRPPEKKVEKKKEPSPEEKLQKLHTDIKFALKVDNPDIEKCLQALDELSSVQVTTHILQKNADVIATLKKIRRYKASNAVMEKATAVYNKLKLQFIGKIETGKPKPNEKNQEEQDAQNTDDSKPVNGESEGERKDVSESESNSKPTDQDNPDENKSPNGIRPDPDEPADQLNDSTEADPTADADVKEDSREQDEQMSSES",
    "output": "May act as a regulator of myogenesis (By similarity). Promotes the repair of DNA double-strand breaks (DSBs) through the homologous recombination pathway by facilitating the recruitment of the DNA endonuclease RBBP8 to the DSBs (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKRKVARKRDKKNIPSGVAHIQATFNNTIVTITDPSGAVVSWSSAGVVGFKGSRKSTPFAAQLAAEDAAKKAMEHGMRNVEVYVKGPGSGRESALRALQGAGLNVVMLRDVTPVPHNGCRPRKRRRV",
    "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAELAKSAVLVSSCTDDLLGDAKQVVVGPNQEDLHSAEAVLNRYSTVGFQASNLARAFSICEMMLTPQSPSPSLMPTEGDQASESPVMVQPTLFVGVTANLFGTGCREAIRFLCTECVPLPNGVEPATPLDDMAGISCDGTGALKPSPCDSRALIHVLVVSGGAMEHDIRRACESYKLSRDGAEEEGEQFHHPVERDRSRSKGTDCHFGNVRYNSSGVASRNLFSCVMRCLVKRLAEAQRKEKANREAAPIPEAYYDVCSWAITPSTLWYMAGLWMADIFTEALQETGEVTDEKVASEEGLKRAKSTVLYWAARNGVPIFSPSLTDGDIMEFILTAGDTGVPLLQLDLVADIHRLNRLAMRSRRTGMMILGGGVVKHHVCNANLMRNGADYAVFLNNAQEFDGSDAGARPGEAVSWGKLRLDSTAVKVYSEVTIVFPLIVVHVFVAWVRMMRSKGKENIRS",
    "output": "In association with the non-catalytic regulatory subunit DHSp, catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF5A precursor protein to form the intermediate deoxyhypusine residue. Regulates protein levels of its regulatory subunit DHSp. Required for cell growth and survival."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRTDLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLSWQAVWEMYCQRHDTPTGSEWLESVRAYEKAILSQRG",
    "output": "Catalyzes the interconversion of L-rhamnose and L-rhamnulose."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENKYLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWIGGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEIQNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDETVLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLALKNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENFDKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGSYLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIAPYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLSQLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKIPSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLSDDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLDTIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIGANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPGLASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDDLIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVETEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLIDYSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEGIPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIGAEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKILVPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSIYSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPGKFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGAGGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDINKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNYLISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILEFYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKVNGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTLVGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDISTSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKVNINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKDIKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFYFDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPDGFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNNSKAVTGWRIINNEKYYFNPNNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKHFYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNSKAVTGLQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILYQNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYDGILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQNKFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAVTGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPANTDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGYKTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIYYFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG",
    "output": "[Toxin A]: Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis . TcdA and TcdB constitute the main toxins that mediate the pathology of C.difficile infection, an opportunistic pathogen that colonizes the colon when the normal gut microbiome is disrupted . Compared to TcdB, TcdA is less virulent and less important for inducing the host inflammatory and innate immune responses . This form constitutes the precursor of the toxin: it enters into host cells and mediates autoprocessing to release the active toxin (Glucosyltransferase TcdA) into the host cytosol (By similarity). Targets colonic epithelia by binding to some receptor, and enters host cells via clathrin-mediated endocytosis (By similarity). Binding to LDLR, as well as carbohydrates and sulfated glycosaminoglycans on host cell surface contribute to entry into cells . In contrast to TcdB, Frizzled receptors FZD1, FZD2 and FZD7 do not act as host receptors in the colonic epithelium for TcdA . Once entered into host cells, acidification in the endosome promotes the membrane insertion of the translocation region and formation of a pore, leading to translocation of the GT44 and peptidase C80 domains across the endosomal membrane (By similarity). This activates the peptidase C80 domain and autocatalytic processing, releasing the N-terminal part (Glucosyltransferase TcdA), which constitutes the active part of the toxin, in the cytosol .; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRSISVLGATGSVGESAFDLLMGAGGPERFRTVALTGGANVARLAQMARALRAELAVTAWPERLADLRAALAGSGIEAAAGPQAVAEAAARPADWTLSAIVGAAGLPPGLEVLNRGGTLALANKETLVAAGPLVMARARETGARILPVDSEHSAIFQALHGENLDSVEHVTITASGGAFRDWPLERLARATVAEASRHPNWDMGQRITIDSASMFNKALEVIEAHEFFGLGVDRLRVLVHPQSIIHAMVTHRDGGSIAHLGAPDMRHAIGYALNWPARAALPVPALDLAALGSLTFAQPDEVRWPALRLAREAIGAGGAAGAVLNAAKEQALDDFIAGRIRFTDMAPAVEHALALAAREAGFAQSPRDLGEVLHWDDFARRAAAQWQGAA",
    "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEQEVNRGLPSTFLTFHSSSFVELLKEYDPTLLPAKRAAETFGEAPHGTTIVAATFAGGVLLAGDRRTTMGNLIAGRDVDKLTITDDYSAVGFAGTVGISIDMTRLFVVELEHYEKIEGVPLSLEGKSNRLAAIVKGNLPMANAGMVSIPLFIGYDLEASDPARAGRIVSFDAIGARYEEKSGYQSIGSGSPFAKSSLKKLHDPGSDDAATLSALIEALYDAADDDSATGGPDMVRRIFPTAIRITAEGAYRYTEEELAAVADAVVARRSADEPGVRSFTAS",
    "output": "Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKKSQLVFAMVAGELSGDILGAGLMAALQKSHPDARFVGIGGPRMEALGFESLFAMEELAVMGIVEVLSRLPRLLKVRASLIKDITALKPDCFIGIDAPDFNIGLELKLKARGIKTVHYVSPSVWAWRPKRIFKIAKATHMVLSLLPFEKAFYDKHQVPCTFVGHTLADDIPLRSDKAAARQLLELDADAEYLAILPGSRGGELKQLAEPFVKAALLIKENFPDIRFVTPLVNQKRRDQFEQALKDHAPDLEIHMVEGKSREVMTAADGILLASGTATLEAMLVKRPMVVAYRVSPLTYRIAKSMMQVNRFSLPNLLAGKDVVPELIQDDCTPEKIAAAVTVELNRDFAPLNAEFERLHQMLRCDASQKAADAVMRLVETKEG",
    "output": "Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALYSISKPVGSKINKHSYQDENTLVGKQALSKGTEKTKLSTNFEINLPRRTVLSDVSNVGKNNADEKDTKKAKRSFDESNLSTNEEADKPVESKFVKKLKVYSKNADPSVETLQKDRVSNVDDHLSSNPLMAEEYAPEIFEYIRKLDLKCLPNPKYMDQQKELTWKMREILNEWLVEIHSNFCLMPETLYLAVNIIDRFLSRRSCSLSKFQLTGITALLIASKYEEVMCPSIQNFVYMTDGAFTVEDVCVAERYMLNVLNFDLSYPSPLNFLRKISQAEGYDAQTRTLGKYLTEIYLFDHDLLRYPMSKIAAAAMYLSRRLLRRGPWTPKLVESSGGYEEHELKEIAYIMLHYHNKPLEHKAFFQKYSSKRFLKASIFVHQLVRQRYSVNRTDDDDLQSEPSSSLTNDGH",
    "output": "Essential for the control of the cell cycle at the G2/M and G1/S (mitosis) transition. Interacts with the cdc2 protein kinase to form MPF. Interaction with res2 promotes the phosphorylation of res1 and inhibits MBF-dependent gene transcription. Forms an autoregulating feedback-inhibition loop with MBF which is important for normal regulation of the cell cycle. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis. Negatively regulates conjugation via interacting with cell cycle 'start' genes. Degraded by skp1, pop1 and pop2 in the G2 and M phases of the cell cycle."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSIHSASPIIRRKSRKIWVGNVPVGGDAPIAVQSMTNTETCDVAATVAQIRRLEDAGADIVRVSVPDMDAAEAFGKIKQQVNVPLVADIHFDYRIALRVAELGVDCLRINPGNIGREDRVKAVVDAARERNIPIRIGVNAGSLEKDLQKKYGEPTPEALLESAMRHVDHLDKLDFQNFKVSVKASDVFMAVAAYRLLARQIEQPLHLGITEAGGLRSGTVKSAVGLGMLLAEGIGDTIRISLAADPVEEIKVGFDILKSLHLRSRGINFIACPSCSRQNFDVVKTMNELEGRLEDLLVPMDVAVIGCVVNGPGEAKEAHVGLTGGTPNLVYIDGKPSQKLTNDNLVDELERLIRQKAAEKAEADASLIARG",
    "output": "Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGDRLTGLHAPTTEAGAASADHTAVVRPGFRDTAKAYVEVTKPISVGLLAFTAAAMMVVAGATHPVSGWLFVQALLAVVLACAGANAVSCYVDRDMDAQMGRTRRRPVPSGRISPPARALYWGLFLFVASLGLAWNLNPIAWITLWGGMLGYVVVYSLWLKRRSVWNIVIGGVSGGMPALFGWAAVTGEISLLPVLIAALVVLWIPNHIWSLAIFYREEYARVKVPMLPVVYELRRALNWLLLTVVLMVVFSVLIYFVGDWGLVYLATALVMGAAALALSVHIYRNPERRKAWVLFKFSSPYLAVLFLSMMVDVWLR",
    "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIDYVSGTLVDKTTDSALVDVNGLGYRVHVPTSTYKRLPDTDEEVTLHTYHYLREDDESLYGFATKAERTVFETMTGVSRVGPKLALSALSAMTPTELRDHVMEGDKSRLTQISGVGTKTADRLIVELRDRLADLDVLEDTSPLSGGSDARAEARADALEALTELGLSKADAERSIRQVLRDNAGIQSADELVRRALKADQE",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEARTTDLSDLYPEGEALPMVFKSFGGRARFAGRVRTLRVFEDNALVRKVLEEEGAGQVLFVDGGGSLRTALLGGNLARLAWERGWAGVVVHGAVRDTEELRGVPIGLLALAATPKKSAKEGKGEVDVPLKVLGVEVLPGSFLLADEDGLLLLPEPPSGVRSGG",
    "output": "Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARNAPAFWQTRSLAARLLLPLSGLFLLLAAVRRQLFRLGIRRAVRLPVPVVVVGNIAVGGSGKTPVVEWLVARLRDAGFTPGIVSRGYGGKAPGAVIVPPHGDVRLFGDEPVLLARLTACPVAVGADRPAAARALLQAYPGCDVIVADDGLQHYPLARDVEIAVVDERTLGNRWLLPAGPLREGPGRLRDVDIIIAHGALSPALSSLLDGRPVFAMHLEGSEFRRLDGAGCRNAEAFRGVRVHAVAGIGRPERFFAQLTRMGLEVVPHPFPDHHPFTAADLDFAPGEPKILTSKDAVKCASFASADTWEFPVKAHIAAGAAERILEKLTHGRPTA",
    "output": "Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFELNNFDALQIGLASPEKIREWSRGEVKKPETINYRTLKPERDGLFCERIFGPTKDWECHCGKYKRVRYKGIVCDRCGVEVTKSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLMLDMSPRSLEKVLYFASYIVIDPKETPLLKKQLLNEKEYREAIENYGEEGFVAGMGAESVQKLLEEIDLNQVSKELKEALKTSTGQKKIRLIRRLEAVESFRKSSNRPDWMIIDVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKKLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKMYQCGLPKEMALELFKPFVMKKLVQGGLSHNIKSAKRMVERVQSEVWDVLEEVISDHPVLLNRAPTLHRLGIQAFQPVLVEGRAIKLHPLVCTAYNADFDGDQMAVHLPLSVEAQAEARFLMLAAHNILKPSDGKPVCVPTQDMVLGSYYLTLDKENAIGEGRIFSSPEEAIMAYQIGDIDIHAHIKVRISKEVDGEEVCGIIDCTPGKLIFNESIPQDLGFVDRSVPGNEVKLEVDFLINKSSLGKLINKCYMKHGPTKTSIMLDKIKEKGYHYSTIGAITVSTSDMVVPEAKKRLLAETDVEVNKIDKMYRRGFISEDERYERVIEKWTKTTDLVADELMKNLDRFNPIFMMADSGARGSKSQIKQLAGMRGLMANPSGKIIELPIRASFREGLDVSEYFISTHGARKGNADTALKTADSGYLTRRLVDVSQDVIVREEDCGSKEGFEISEIREGNEIIEPLSERLTGRYSAEDIIDPNTGEILVKKEEYIDGEKAEEVEKSGVKKIKIRSVFTCKSKHGVCAKCYGMNMATAEKINIGESVGIIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRVEELFEARKPKGLAIVSEINGTIRIDETKKKRTVVVIGETEEISYDIPFGSRLKVSNGDVISAGDEITEGSVNPHDVLRIKGPNGVKNYLLSEVQKVYRLQGVDINDKHLEVVVRQMTRKIKIEESGDTEFLPGTMVDIFDFQEENAKAEEEGKETAKGRITLLGITKAALATDSFLSSASFQETTRVLTDAAIKGKVDPLLG",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MWVSWAPGLWLLGLWATFGHGANTGAQCPPSQQEGLKLEHSSSLPANVTGFNLIHRLSLMKTSAIKKIRNPKGPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQVTDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPLGPRRPMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEILPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSEVDAQLTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPFG",
    "output": "Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSSARKLAPLPRVFVVGVGMTKFVKPGTEDARDYPDMAKEAGQKALADAQIPYSAVEQACIGYVYGDSTCGQRAVYHSLGLTGIPIINVNNNCSTGSTALFMGRQLIQGGMAECVLALGFEKMERGSLGAKFPDRTNPMDKHLDVLINKYGLSAHPVAPQMFGSAGKEHMEKYGTKIEHFAKIGWKNHKHSVNNPYSQFQKEYSLDEVMSSRPIFDFLTVLQCCPTSDGAAAAILASEEFVKKYGLQSKAVEILAQEMVTDFPSSFEEKSIIKMVGFDMSKEAARRCYEKSGLRPSDIDVIELHDCFSANELLTYEALGLCPEGKGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGLGGAAVVTLYKMGFPEAASSFRTHQIEAAPTSSAGDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITIADSDLLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQNLQLQPGKAKL",
    "output": "[Isoform SCPx]: Plays a crucial role in the peroxisomal oxidation of branched-chain fatty acids. Catalyzes the last step of the peroxisomal beta-oxidation of branched chain fatty acids and the side chain of the bile acid intermediates di- and trihydroxycoprostanic acids (DHCA and THCA) (By similarity). Also active with medium and long straight chain 3-oxoacyl-CoAs. Stimulates the microsomal conversion of 7-dehydrocholesterol to cholesterol and transfers phosphatidylcholine and 7-dehydrocholesterol between membrances, in vitro (By similarity). Isoforms SCP2 and SCPx cooperate in peroxisomal oxidation of certain naturally occurring tetramethyl-branched fatty acyl-CoAs (By similarity).; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPATILIGAQWGDEGKGKATDLLAKDIDYVVKFNGGNNAGHTVVIGGDKYVLHLLPSGILNENVVPVIANGVVINPEVLFDEIATLNSRGVNTDKLVISANAHIIAPFHRTIDLVTERFLGKRQLGTTGRGIGPTYADKINRIGIRVQDLFDKSVLRQKIEGSLSNKNHMLVKVFNRRSVSVTEMLDYLLSFAERMRPMIADTSLLLNNALDCGKHVLFEGGQATMLDVDHGSYPFVTSSNATVGGAITGAGIGPTRVNKVIGVAKSYTTRVGAGPFPTELHDEYGEWLQKRGYEVGATTGRKRRCGWFDGVVARYATRINGITDYVLTKLDVLTGLDRIPICVGYKVGDSVFREMPVSQSDFHHAVPIYEDLPGWQCNISECESFDSLPPEARGYVLALEDLIKARISVIGTGPERENIIIRHPLGIF",
    "output": "Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSGTLVLVRHGQSEWNLKNLFTGWRDPDLTELGVEEAKAGGAALAEYGIKFDIAFTSVLVRAQRTCQMVLDAVGQSSLETICDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDVPPPGGESLRDTGARVWPYYLTEILPRVLAGEKVLVAAHGNSLRSLVMVLDRLTKEQVLNLNLATGVPMVYKLKADSTVASKEVLGDMSAAH",
    "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGQKVNPIGLRLGINRTWDSRWFANKGEYSKLLHEDMRIREVLMKNLKQAAVSKIIIERPHKKCRVTIHSARPGVVIGKKGADIDKIRKLVSKLTDSEVVINIVEVRKPEIDATLVADSIAQQLERRVAFRRAMKRAVQSAIRLGAEGIRINCSGRLGGAEIARLEWYREGRVPLHTLRADVDYGVATAHTAYGTCGIKVWIFKGEILEHDPMAQDRKMAELDHAGGGGGGERRRRERDAA",
    "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKVIGIDMGTTNSCVAVMDGKNAKVIENAEGARTTPSIIAFTDGDERLAGQPAKRQAVTNPEGTLFAVKRLIGRRYDDPMVTKDKDLVPYKIVKGDNGDAWVEVHGKKYSPSQISAMILQKMKETAESYLGETVTQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKSEGKTIAVYDLGGGTFDVSVLEIGDGVFEVKSTNGDTFLGGEDFDIRLVEYLVAEFKKESGIDLKNDKLALQRLKEAAEKAKIELSSSQQTEINLPFITADQTGPKHLAIKLSRAKFESLVDDLVQRTVEPCKAALKDAGLKAGEIDEVVLVGGMTRMPKIQEVVKAFFGKEPHKGVNPDEVVAMGAAIQGGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIERNTTIPTKKSQTFSTAEDNQSAVTIRVFQGEREMAADNKLLGQFDLVGIPPAPRGVPQIEVTFDIDANGIVNVSAKDKGTGKEHQIRIQASGGLSDADIEKMVKDAEANAEADKKRRESVEAKNQAESLVHSTEKSLAEYGDKVSADDKKAIEDAIAALKTSLEGEDAEDIKAKTQALAEVSMKLGQAMYEAAQAAEGAGAEGGEQASSSKDDVVDADYEEIDDNKKSS",
    "output": "Acts as a chaperone."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMAAKREHADCGAEPARKRVKENYKRVTGKLLSKMTISLENHLYYTFTFRLLNENKTEAYYGNLQCFKDLVEQECYDVSLNFVKTKYNERIEINEYSKCDAAIDENVAVKLCLTRADFENEEIVNVLAKLKCVFKRLGANNYKMVFDINMQDAGGAVFVQQVECFANLKVLASAAKAFVKSPDNFNSLMDFYYKNTNTLFYVHGVRCQHTSKGQNEFLNWTAGPSTSLETPSNTDNEDYINLVHSHSTNNISRANKHLKSMQLSLFKAEQKINDNGKHSFSVQFKTLDSMDDDDDTKWHKCVYYVDSNGNKEDPNDTNAVQKLAMDFDQLATCLADKLTKATIFVTADNADASTMNLLGLLKHDDEECEYQFL",
    "output": "Required for late and very late gene expression. Lef-3 could be a single-stranded DNA-binding protein."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETDGYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAAGDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAGRMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK",
    "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQSKFLWIAAASAATAAAQVPARLCGTAQPTMDDLVIAAGLAAEGKDNRRGLHPEDPIVVPTLFHVLAINETVAGGYLTEKSLQDQLDVMNADFGPSNVIFNLTATTRTVNRRWAQDLDEIPMRRALRQGGQETLNIYFMPYVSGYLGYCTFPNFWDAGSDEFIYDGCAVLSDSLPGGSLARYNLGRTATHEIGHWFDLFHTFSGGCGCVGDMIHDTPAMLNATGGCPVGKDTCPDRPGLDPIHNYMDYSDDACMNEFTPGQNFRMRSAWYNIRTK",
    "output": "Secreted metalloproteinase that allows assimilation of proteinaceous substrates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIPNHILILGSPNSGKLRVSKLISNDKDFPEIKENESHSGIIIKTSLSTKYYHIKLNILIDEYPEERNKSVTDEEKLLELEKWFNEFKSEEFGELREVLDGLVFTVNMKADSLEFIEKALETVSEIRTSLGDEESQWDGFISIIGSTTQGESVDDDTVEEIEDLVITHGFEFINLNTQGINEFKEKQGKDRVVELIESHEWTNMELLKVNPDQYEKNKMNKVEQMKQNLLEEKESMDLDVVFSKLSVAKERAEDMTQEQKEKYANEIIEEIIDFI",
    "output": "Involved in gross chromosomal rearrangements (GCRs) and telomere healing."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPNKEVLDNASLQRALTRITYEIIERNKGGKNLVLVGIKTRGEYLARRIADRLEQLEGVQIPVMAIDITNFRDDKPDQHNDLGLNSEERLNISEQNIVLIDDVLFTGRTIRAALDALIHIGRPKTISLAVLVDRGHRELPIRADFVGKNIPTAQNEKIKVFVQEIDGKDAVEIVH",
    "output": "Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAQEGGAVEQFGQWLWSNPIEQDPDDEMVDAREEEGQILYLDQQAGLRYSYSQSTTLKPTPPGQSNSAPVYRNAQRFQTEYLSPTTVTRSQVSVLSLSHTRPQLRPALSLLNSTPRANNQPWVATLIPSQSAGPPQRSSEPKRLTGRNSRNQR",
    "output": "Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSAIETKKVVVEEITSKLKESKSTIIVDYRGLNVAEVTELRKQLREANVEFKVYKNTMTRRAVEQAELDGLNDFLTGPNAIAFSTEDVVAPAKVLNEFAKKHEALEIKAGVIEGKVSTVEEVKALAELPSREGLLSMLLSVLQAPVRNLALATKAVAEQKEEQGA",
    "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVAQTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS",
    "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKRKICKALICAALATSLWAGASTKVYAWDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDNSWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTAGCKTNEAFYTDILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFSDAYKPENIKIIANGKVVVDKDINEWISGNSTYNIK",
    "output": "Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Constitutes an essential virulence factor in gas gangrene. Binds to eukaryotic membranes where it hydrolyzes both phosphatidylcholine and sphingomyelin. The diacylglycerol produced can activate both the arachidonic acid pathway, leading to modulation of the inflammatory response cascade and thrombosis, and protein kinase C, leading to activation of eukaryotic phospholipases and further membrane damage. Acts on human and mouse erythrocytes, but not on rabbit or horse erythrocytes."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA",
    "output": "Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MYEYLDRRYALALYEVAEENNKVDEYLRDLKEVVNIIKNSEDICKILKHPEINTSRKKEIFTELFKDKVDNKILSFLLVLIEKDRILYLEEKLKEMEKIYLEKNNMILANIKTVIPLLKEEREELIEKLGNKYNKKIILEEEIDKSIIGGVYVRVGDDVLDGTLSTRLKDIKKMMLKRE",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEEKKVVRALSEHLSLPPPPSPSVAVAINGKKKSKYVVFWALEKFIPEGFTDFKLLYVRPPVSYIPTPMGIAVAVSELREDVVSAYKQELDWSANEMLRPYKKMFERRKVQVEVLLLDSLEPAAAIAEEIAGTGVTKLVIGMSLRGFFSRKIDMSSLIATAVPRFCTVYVISKGKLASVRPSESDASGSIRFERSSSTSGSTDSPRLPPEYQDFLSAVSEAQSRVSPFSPALKHSMGSNAVAQMDTSSSGTDQEEVSTGRGMEIVHSGIEGKKNKDESFSASFPMGTEAYNSMSWTSKWRDHEDRREMRSSSSSNNHDLVNMDWGAVVPENYSWVSHTASHMSDGLLSVHSITDNQVNLNFEIEKLRAELKHVQEMYAMAQTETVGASKKLTELNQRRFEESEKLVELKEKEEVAKDTASKEKQRYEEAMKEAEKVKELMMKEALHRREAEFKAERDAREKDKLQASLVSPGVQYQHYTWEEIAAATSDFAENLKIGIGAYGSVYKCNLHHTTGAVKVLHAGETQLSKQFDQELEILSKIRHPHLVLLLGACPERGCLVYEYMDNGSLDDRLMLVNDTPPIPWFERFRIALEVASALVFLHKSKPRPIIHRDLKPGNILLDHNFVSKLGDVGLSTMVNQDDVSSRTIFKQTSPVGTLCYIDPEYQRTGIISPKSDVYSLGVVILQLITAKPAIAITHMVEEAIGDDAEFMAILDKKAGSWPISDTRELAALGLCCTEMRRRDRPDLKDQIIPALERLRKVADKAQNLLSRTPSGPPSHFICPLLKGVMNEPCVAADGYTYDREAIEEWLRQKDTSPVTNLPLPNKNLIANYTLYSAIMEWKSNKR",
    "output": "Functions as an E3 ubiquitin ligase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITITQGLAVSTISSFFPPGYQVSFCLVMVLLFAVDTGLYFSVKTNIRSSTRDWKDHKFKWRKDPQDK",
    "output": "Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG). Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC). Does not bind free monomeric IgG, thus avoiding inappropriate effector cell activation in the absence of antigenic trigger . Mediates IgG effector functions on natural killer (NK) cells. Binds antigen-IgG complexes generated upon infection and triggers NK cell-dependent cytokine production and degranulation to limit viral load and propagation. Involved in the generation of memory-like adaptive NK cells capable to produce high amounts of IFNG and to efficiently eliminate virus-infected cells via ADCC . Regulates NK cell survival and proliferation, in particular by preventing NK cell progenitor apoptosis . Fc-binding subunit that associates with CD247 and/or FCER1G adapters to form functional signaling complexes. Following the engagement of antigen-IgG complexes, triggers phosphorylation of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapters with subsequent activation of phosphatidylinositol 3-kinase signaling and sustained elevation of intracellular calcium that ultimately drive NK cell activation. The ITAM-dependent signaling coupled to receptor phosphorylation by PKC mediates robust intracellular calcium flux that leads to production of pro-inflammatory cytokines, whereas in the absence of receptor phosphorylation it mainly activates phosphatidylinositol 3-kinase signaling leading to cell degranulation . Costimulates NK cells and trigger lysis of target cells independently of IgG binding . Mediates the antitumor activities of therapeutic antibodies. Upon ligation on monocytes triggers TNFA-dependent ADCC of IgG-coated tumor cells . Mediates enhanced ADCC in response to afucosylated IgGs .; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGDVILSPVSTEKTALLAEKENKLTLIVDRKATKEDIKREVESRFSVKVEGINILITKKGKKAIVKLAKEYSAEEIAERIGVF",
    "output": "Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGQKVNPIGLRLGINRNWESRWFPTKANLVENIGEDYKIRAFLKRKLYYAGISQILVERTAKKLRVTVVAARPGIIIGKKGSDVDNLRKELQDLIGKDVNINIKEERKAGASAQLAAESVATQLEKRIAFRRAMKKVIQGAQKAGAKGIKVSVSGRLGGAEMARTEWYLEGRVPLHTLRAKIDYGFAEARTTYGNIGVKVWIFKGEVLHKGMQPEKTEESAPAKKPRRTRRGK",
    "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNLLDKVDAASLRDDIPAFRPGDTLNVHVKVIEGSKSRIQVFKGVVIRRQGAGVRETFTIRKVSFGIGVERTFPVHTPNIDKIEVVTRGDVRRAKLYYLRDLRGKAAKIKEKR",
    "output": "This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKSYLSNDTEAKLKKTKDLPPHIHFIGIGGIGMSALAMILAQKGYSISGSDQKKNLTLKKLEENKVHIFPTQVESNIDEILKVHGKNILVVKSSAIHQDNFELCKAKKYNLKIKHRSEILAFLIEQKKSIIVSGSHGKTTTSTYITTLFSYANKSPTAIIGGIVPLYKSNYSCGNSEFLIAEADESDGSLVKFNPNIGLITNLELEHVDHYLDLEDLIETMKQFAQKCECLITNFDCDNLRDNIHGSKWFSIQKIINIDFALIPKESNGCEIIAEYYEKEKFIDVIKIPVPGIHNLSNAAAAIAACRVAGILFKDIKKGIEKLKLPSRRFEFKGLWRNRLIVEDYAHHPSEIDAAISIASTIIETKHKLSKILPRRIVTIFQPHRYSRTKKFQKEFAKSLSKSDLVFITPIYSAGEDKIEGINNKSIGHELKKINPNLEIYTPDNNQNLIKLIKEQTIENDLILIMGAGDINLISENLFLELINNKLISNDIAA",
    "output": "Cell wall formation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPDMPLRILVETIERLELVTARTQLVAFLVNLFKQTPPEIIDKVVYLVQGILWPDWKGMPELGVGEKMLIKAISLACNISEREVEKTAKEIGDIGKATEKLKQTAQSKQTGLTIFAFTQQPTGLTVTNTYNTLVKIAMAQGEGSKDLKIRLLAGLLKDASPKEAKFIVKFVEGKLRVGIGDATIMDALAVTFGGGVANRPVIERAYNLRSDLGEVAKILASKGIEELKKIKPEVGVPIRPMLAERLSDPREILVKTGGEAFVEYKYDGERAQIHKKGDKIWIYSRRLENITSQYPDVVERALEKIKADEAIVEGEIVVYDPDTGELKPFQELMHRKRKHDIRQAIKEYPVKVFLFDLLYLNGEDYTLKPLPVRREALEKIIDKTEDFTIAEYIKTSNPEELEKFFLEAIGNGVEGVMAKAIHKDSIYQAGVRGWLWIKYKRDYKSEMADTVDLVVVGAFYGKGRRGGKYGALLMAAYNKEKDVFETVCKVGSGFKDEDLDKLPDMLKPYIRDRKHPRVVAEIEPDVWVDPVLVAEIIGAELTLSPIHTCAKGVIKPDAGISIRFPRFIRWRPDKRPEDATTSSELVEMYQRQLKKITTEQATQEQL",
    "output": "DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Can use ATP, ADP and GTP, but not CTP, TTP or NAD(+)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAAVGSGGSTATAGPGAVSAGALEPGTSSAAHRRLKYISLAVLVVQNASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYMDTLKLAVPSLIYTLQNNLQYIAISNLPAATFQVTYQLKILTTALFSVLMLNRSLSRLQWASLLLLFTGVAIVQAQQAGGGGPRPLDQNPGVGLAAVVASCLSSGFAGVYFEKILKGSSGSVWLRNLQLGLFGTALGLVGLWWAEGTAVTHRGFFFGYTPAVWGVVLNQAFGGLLVAVVVKYADNILKGFATSLSIVLSTVASIRLFGFHVDPLFALGAGLVIGAVYLYSLPRGAAKAIASASAPTSGPCTHQQPPGQPPPPQLSSHHGDLSTEPFLPKSVLVK",
    "output": "Transports uridine diphosphate galactose (UDP-galactose) from the cytosol into the Golgi apparatus, functioning as an antiporter that exchanges UDP-galactose for UMP. It is also able to exchange UDP-galactose for AMP and CMP, and to transport UDP-N-acetylgalactosamine (UDP-GalNAc) and other nucleotide sugars. As a provider of UDP-galactose to galactosyltransferases present in the Golgi apparatus, it is necessary for globotriaosylceramide/globoside (Gb3Cer) synthesis from lactosylceramide."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEKEVIVVGAGLAGSEAAYQLAKRGIKVKLYEMKAKKKTPAHSKDYFSELVCSNSLGSDSLENASGLMKEELRILGSLLIEVADKNRVPAGQALAVDRDGFSEEVTKILKNTKNIEIIEEEFTEFPNDKIVIIASGPLTSDKLFQKISEITGEESLYFYDAAAPIVTFESIDMNKAYFQSRYGKGDGEYINCPMNKEEYYNFYNELIKAERAELKNFEKEKLFDACMPIEKIAMSGEKTMTFGPLKPKGLINPKTEKMDYAVVQLRQDDKEGKLYNIVGFQTNLKFGEQKRVFSMIPGLENAEFIRYGVMHRNTFINSTKLLDKTLKLKNKDNIYFAGQITGGEGYVTAIATGMYVAMNVANRLENKEEFILEDISEIGAIVNYITEEKKKFQPMGANFGIIRSLDENIRDKKEKYRKLSERAIEYLKNSIKGV",
    "output": "Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKLHELKAAEGANKASKRVGRGTGSGLGKTSGRGQNGQNSRSGGGVRPGFEGGQMPLYRRLPKRGFKNIFAKEYAAINLDRLNCFEDGTVVTPELLVEKRVVKKVKDGVKILGNGNIEKKLTVKAAKFSKSAIEKIEAAGGKVEVI",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MYFFIKTINKYLYKLIYSFIVFYQKIISPILPARCRYYPTCSNYGKQALAWYGVWNGSLLLLKRIGRCHPLGGHGIDFVPLPLASYHYQHVSLIMSACMKAQGLYVYRDNNGYVARLNHMMKLT",
    "output": "Could be involved in insertion of integral membrane proteins into the membrane."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MITKIDKNKVRMKRHARVRSKLAGTTERPRLNVYRSNKHIYAQVIDDVKGVTLAQASTQDKNLGLETTSNVEAAAKVGEAVAKLAVEKGVKAVVFDRGGYLFHGRVKALADAARENGLEF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLKPRAAEGAAVALLRLLLLLLLLPPELRDRGLGVAGAAGAGLPESVIWAVNAGGEAHVDVHGIHFRKDPLEGRVGRASDYGMKLPILRSTPEDQILYQTERYNEETFGYEVPVKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNGHVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSVQGEVSTFTGKLYIEFVKGYYDNPKVCALYIMAGTVDDVPKLQPHPGLEKKEEEEEEEEYDEGSNLKRQTNKNRVQSGPRTPNPYASDNSSLMFPILVAFGVFIPTLFCLCRL",
    "output": "Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNSLEAGRVLSVLDEALEGIRLISYVTQDVLDTAEQLRDMLGEDLANALIKHRQLIQSAKSTLNNDQVQASTLELVRLLKKSPSAQRLQVLPYERTYGILQTLQYFEQLRQFAQKRLTTTVEEDSSNREFFEEVRDREERAVAEQEQLKQKLKLQRVELQKAAGTIQVSEDRARGEVSEVQSSTQQSRAAIEGSARAQSEADKSSFQSDLDQVTKELAAARAELARLRQEHKDNEALLRKARKRAEQDVEVQIGEYDADVGAKEEELGKARAEYEEVLRQLQEYNSGWSEMYQERLEYEERERRLADQRFQAALLAVRQNHAARVIQSYWRGFKKAREAAKKKAKKLEKAKAAKKK",
    "output": "Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLEFMDYVQFAFYNATKWNYENSYSQLTATAKGLLDFETPGGLRFNLSSLSSPNFATSYALGSVGLVDGSLSYLYSSLPLRTTAQSAKIDLHEIIRGYRQIQELRRVDEPWMLEQWHGGRRIDKRDTLLYGRLYLPQSTLEALYLRRITPTQQVRITAVSDSRLRNGGTILALHQYDTGKYSTETLYSTDGGLLGLRGLYNFGPDPRKEVTEPPKQMPRIDDKFYGRFSAGAELYYGTLNKSGGVSVGGRFATLPAHRGIPLTATLTLNPLMGNISSTYAVRAGKNLSLCSRLDFNVYSYESDLVLGCELWKMRAPVEERRERSMEAKLAWRLDEVDLEKEKKPEEVAGVLKARVDQNLKVGLVWEGRVKELLFTLGTSIDMKRRDQPFRALGLELQYSS",
    "output": "Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins. Can associate with the SAM(core) complex as well as the mdm12-mmm1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKQARAVQTWRSIVDAAASVFDDYGYERAAISEILRRAKVTKGALYFHFASKEAIAQAIMDEQTSTVEFEQEGSPLQSLVDGGQQFAFALRHNSMARAGTRLSIEGVFLGGPHPWGDWIDATARMLELGQERGEVFPQIDPMVSAKIIVASFTGIQLVSEADSGRADLRGQVAEMWRHILPSIAHPGVIAHIKPEGRVDLAAQAREKAEREEQEARIAAEAKGAGSDAATDSGSRSGGSGLRGGGSGRGPRAGGAGDEGDEEPAGAGVAAGGVVA",
    "output": "Represses adpA expression by binding to the promoter region in the absence of A-factor, causing repression of streptomycin production and of sporulation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSLYYANALFSKYPASSSVFATGAFPEQTSCAFASNPQRQGYGAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTAGPGTTAQDRAEAEEEEEE",
    "output": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVPPPPSRGGAARGQLGRSLGPLLLLLALGHTWTYREEPEDGDREICSESKIATTKYPCLKSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTDNFGRVLCTCYPGYRYDRERHRKREKPYCLDIDECASSNGTLCAHICINTLGSYRCECREGYIREDDGKTCTRGDKYPNDTGHEKSENMVKAGTCCATCKEFYQMKQTVLQLKQKIALLPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHRTHSSAEEFPLPQEFPSYPEAMDLGSGDDHPRRTETRDLRAPRDFYP",
    "output": "Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTPAVSPAHTVLFEAKARKGISFEQIGKAIGRDEVWVASAFYGQAKFNEEELKKLSEVLEISSAQIVKELGDQWFPNRGLGPVPPSDPVIYRLFEGVLVYGHPIKAIIHEKFGDGIMSMIDCNINVERKPDPKGDRVVVTFDGKFLPYSKW",
    "output": "Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKPSSSRASFAQRHWQHDGWLATLLRPLSALTAWHVARRRAQYQTGRRPVYRAPVPVMVIGNIYVGGTGKTPVVIATVQALRERGWTPGVISRGYGARIGPQPRVGQGRELTPASHGDEPALIAHATGAPVAVHPRRALAAQALLSQYPQVDVIVSDDGLQHLAIARDIEIAVQDDRGIGNGRLLPAGPLREPAARLDTVDAIITNRAPQSSATPTAASGQGPRRADMRLEPEAARHLQSGARRPLADFADARAFPAVAAAAGIGNPERYFATLRAAGLHPEPCLALPDHYDYRRSPFEAIVADAILVTSKDAIKCRGLDDPRLWEVPVQARLSDPGLFDWLEARLRQAAAAIAR",
    "output": "Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTHQTHAYHMVNPSPWPLTGALSALLMTSGLTMWFHFNSTILLMLGLTTNMLTMYQWWRDIIRESTFQGHHTPVVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGHRNHMLQALFITIALGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSSHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS",
    "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSNGAFDAIFEYAWGQIDKPISGDFIYGKDLPKLIEIIENIFQKAQKSGSYELRLPLFSEINKDLFRTFSNTKTFFKIHKEEFDDIFFNLVNHPLREILENAFIGVDSIPSDFIVSMNLNSPSKFLVENKSKNTEGAGISTPRKKLTESPIKLLSRNNIGKALEVQVEELKRELTAKQSLLQENERQVSELKIRLETYQEKYASIQQRFSDLQKARQVEDNQNSSRTSDPGSPLVTGIDQKAILEEFRRRLQRQTDTISFLKDQIRRERGLNCSNDKVSHSKRKHATTDGDGTFKNFISAVPSNIWVKATIRIIVCFALLAGVLPYIRKYVYAHDTPSQNSRLQLSWWENSGILSKIVWFFEDQTDLETEYRSNANVDDAYSRVFGI",
    "output": "Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTSQVVPLSTFVQHLESCEGYEFRTMIKMLASPAYAKQQLLKDELSVFMAKVLKLLRSKDDYQVWKGCHIATVFCTYNPVVLCSFGGELMGILYRALEDATKYYGDSVQTEQRKVMVRALVKTLDTLMDLIRGKPSLTREALTPHLSAIIPMLISFGRCEPNLSLPVIKKLLSKHSTTFRPHVGKLKQLLTELYGHYQSLDPVTRKVVCDTAAYLHLTQKPGNNANEHQAHHKSFPDEHWRAGLFSVLSQFGPVVRLWGEILDIGSDENLARLLETLPRDTANDTSPLLPALTVDINKPVTLWHISARLEQLTDMVESFIRLPTLFPTRIPLGELVKVSEILLSLTTNYLPLKRGLRRDAALTGSIRSALPETQLQGIRLLRCLSDHIGKNLITYMPAILSSMELFIPLKDKKTSIDYQKCVDLQNGLLQLTALMNSIAQHLGHKVEEMSLAIKLVDICAYIIEHKQNLDSAFSSTSGTAKAAGGAKKKEYKAKTGSMSDLFSHPHKFLHPVPLENYTVVNTYYNMALTHWKLPSTQQAKITKYCIYYSLSFKEKLGYIPQTFIELLNTIVLFPGKDRFSILPIAVHLLKETGDPVFDVLCNPKLPLEMIQIRRQPTSSEDDTATSEAEEYAAPADQDDEHLSDDEHTTVDDGVATNAVMGLNNLVSSETLRSEQDSALETQHPEQARTSNLVPDEASEGREDARIFKKRSSSDEQDPPSKRTRAVAAQTPVPAAVPVDNGEPESDDGSDFEIPEIELSDADEE",
    "output": "Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTPEEQLRIIKEGTVEIIEEEELLKKLKEGRPLRVKAGFDPTAPDLHLGHVVLLQKLRQFQQLGHEVFFIIGDFTAMIGDPTGRSQTRPPLSREQVLENAKTYEHQVFKVLIPEKTTVVFNSTWLEELGTKGLIELCAKYTVARMLEREDFSKRFKEGIPIYIHEFIYPLLQAYDSVAIKADVEIGGTDQKFNLLIGRDIQREYGQEPQVCITLPLLVGTDGVRKMSKSYGNYVGITEDPKTMFAKIMSIPDEIMWDWFLLLTDYNKEEIEKMRREMHPMEAKKLLAFTIVKRFHSEEEARKAKEWWEKTFSQREFPEDAPLVKLNEKKLRAVDFLVKIGAVKSKNEARRVIQGGGLKINGEKVTDPNTEIEINGELKVKVGKKKFYRVVSG",
    "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MENKKTIYFLCTGNSCRSQMAEAWGKKYLGDKWNVLSAGIEAHGVNPNAIKAMKEVDIDITDQTSDIIDRDILDKADLVVTLCGHANDVCPTTPPHVKRVHWGFDDPAGQEWSVFQRVRDEIGARIKKYAETGE",
    "output": "Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEDFVRQCFNPIIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFVEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCFQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFEDCKDVSDLKQYDSDEPEPRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPEGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALK",
    "output": "Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKEKSKNAARTRREKENSEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRVVFPEGLGEAWGHSSWTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIYEYIHPADHDEMTAVLTAHQPYHSHFVQEYEIERSFFLRMKCVLAKRNAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDTFHLRCAHHLLLVKGQVTTKYYRFLAKHGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQISASKPAFSYTSSSTPTMTDNRKGAKSRLSSSKSKSRTSPYPQYSGFHTERSESDHDSQWGGSPLTDTASPQLLDPADRPGSQHDASCAYRQFSDRSSLCYGFALDHSRLVEERHFHTQACEGGRCEAGRYFLGTPQAGREPWWGSRAALPLTKASPESREAYENSMPHIASVHRIHGRGHWDEDSVVSSPDPGSASESGDRYRTEQYQSSPHEPSKIETLIRATQQMIKEEENRLQLRKAPSDQLASINGAGKKHSLCFANYQQPPPTGEICHGSALANTSPCDHIQQREGKMLSPHENDYDNSPTALSRISSPNSDRISKSSLILAKDYLHSDISSHQTAGDHPTVSPNCFGSHRQYLDKHAYTLTGYALEHLYDSETIRNYSLGCNGSHFDVTSHLRMQPDPAQGHKGTSVIITNGS",
    "output": "Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEQLLRAELRTATLRAFGGPGAGCISEGRAYDTDAGPVFVKVNRRTQARQMFEGEVASLEALRSTGLVRVPRPMKVIDLPGGGAAFVMEHLKMKSLSSQASKLGEQMADLHLYNQKLREKLKEEENTVGRRGEGAEPQYVDKFGFHTVTCCGFIPQVNEWQDDWPTFFARHRLQAQLDLIEKDYADREARELWSRLQVKIPDLFCGLEIVPALLHGDLWSGNVAEDDVGPIIYDPASFYGHSEFELAIALMFGGFPRSFFTAYHRKIPKAPGFDQRLLLYQLFNYLNHWNHFGREYRSPSLGTMRRLLK",
    "output": "Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate . Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions . Involved in intracellular deglycation in erythrocytes . Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function (By similarity). Also able to phosphorylate psicosamines and ribulosamines ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKQNIKRNWIWILIVMIVIGIILYFSIRNLFSTKVAEWSISELLNNIERAKENTTDALYFKEITVNPFTNSITGVFNNTDNTSTSFVTYTNLDLLRLSGVASDQGVISKIFTPEVFLTANNVSGSLKSVATPQPNPFLGILISSVPVLILIFVMVWIYRSQVKMMNGQGGAFGGDKGTAQIIKSDKKFTDIAGNKEPIEEISEVVDYLKNPGKYQQSGARMPHGILLGGPPGTGKTLLAKATAGEANVPFYFVSASSFVELFVGMGAKRVRQVISEARKNSPAIIFIDELDAIGRTRGSGIGGGHDEREQTLNQLLVEMDGMKENSGLLFIAATNRTDVLDPALIRPGRFDRIITVGLPDVKEREEILKLHAKGKRFESNVDFANIAKRTPGFSGAQLENVINEAVLLSIREDTKVINLYQIDEAIDRVMSGPAKKSRTITKEELTMVAYHEAGHAVVGIKVPGGNKVQKITIIPRGNAGGYNLMMPENEKYNYSKADLYATIASFMGGRAAEEIIYGDNKISTGAADDIKKATSIARRMVTQFGMSDLGPIEYQSDEGSPFLGKALASNSSLSNQVNHEIELEIRKIIFTAKEQATKIIKQNIELLELIKESLLKKETIVGEEIEYIAKHMKLPPEKIEEKDLSKNSEDNNLDSLIEKTSKKE",
    "output": "Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTSVYESLLSDYPDKGVIGKPEIRDTETEIIEKLRTLYNHFVQAKQTGKPIFVLIGAGVSTGSKLPDFRGKQGVWTLQAEGKHAEGVDFQVARPGVSHKSILALHKAGYIKTIITQNVDGLDRKVGIPVEDLIEVHGNLFLEVCQSCFSEYVREEIVMSVGLCPTGRNCEGNKRTGRSCRGKLRDATLDWDTEISLNHLDRIRKAWKQTSHLLCIGTSLEIIPMGSLPLDAKSKGIKTTTINYQETAHEKIVETAIHADVKLILYSLCNALGVNVDLGDDLPDEVPIPLKIS",
    "output": "NAD-dependent protein deacetylase."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDKQAERGQSAGPVKTPQGTQPPAHNYTYHTNAAQRAVYDYLKNVKPIPELAEPKTYKTYEEASVEAVLYPIIEKHQVIMVAGAFFGDEGKGKTVNAVANHPGCTFIARVNSGENAGHTVYDDAGRKFVFNLAPSGLLSKGKRNYVGPECVMDPISFMENEVKQLIEANVPYKEQLFIGNVSIVTPYHKLLDLLASAPNSSTLKGMAPIHASKVTKRGIRLDHIFNDQSVLRSRLRKDIDTYFGFLKVKGLSDADVLRRCEKENGDGVVRVPPYVVEFVQAEDKVEYLVKLYMDRVRNNKNFPARCDVAHELRSALSRGEKVMLEGPQSYWLSNAREKFWESTTSADTTASGLLATAQYNFQLYSSVVINVHKAPGSSRVGVGANPSSFVAQDYFSATGVKTLRDLPENMCVDFDSIQKLFFTKAFHPETKEYNGIWEPLEFEDSTGKYNIGVAMAVASSRQHGECGAVTKKPRVCGFFDCVLQYEVNAVQGPYLSISALDRGDDYDKLGVTIAYVYYNGKNDEVLNINGREYKNGDIIKAGEAVPGEVALYYCHPIVKLINGWKQTPIAASKRKPGDPLPRGVCEFLSTVEYFTKAKIISIGNGPRGKDIIYIKQ",
    "output": "Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEVGIDFGTTFSTICFSPSGVSGCTPVAGSVYVETQIFIPEGSSTYLIGKAAGKAYRDGVEGRLYVNPKRWAGVTRDNVERYVEKLKPTYTVKIDSGGALLIGGLGSGPDTLLRVVDVICLFLRALILECERYTSTTVTAAVVTVPADYNSFKRSFVVEALKGLGIPVRGVVNEPTAAALYSLAKSRVEDLLLAVFDFGGGTFDVSFVKKKGNILCVIFSVGDNFLGGRDIDRAIVEVIKQKIKGKASDAKLGIFVSSMKEDLSNNNAITQHLIPVEGGVEVVDLTSDELDAIVAPFSARAVEVFKTGLDNFYPDPVIAVMTGGSSALVKVRSDVANLPQISKVVFDSTDFRCSVACGAKVYCDTLAGNSGLRLVDTLTNTLTDEVVGLQPVVIFPKGSPIPCSYTHRYTVGGGDVVYGIFEGENNRAFLNEPTFRGVSKRRGDPVETDVAQFNLSTDGTVSVIVNGEEVKNEYLVPGTTNVLDSLVYKSGREDLEAKAIPEYLTTLNILHDKAFTRRNLGNKDKGFSDLRIEENFLKSAVDTDTILNG",
    "output": "Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Two movement proteins, p6, Hsp70h and three structural proteins, CP, CPm, and P64 are essential for cell-cell movement. Also plays a role in virion formation. Together with CPm and p64, encapsidates the 5'-terminal portion of the viral genome (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTNIGSLLVDAAALMVTGMGVVFIFLTILIFLVRLMSKLVPQEVPPPITAPKAVKNQANHTSTVSPQVVAAISAAIHQHRASVAK",
    "output": "Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAVSQTTLWNLISGILGVICLLLMTTMGILLKNLLLTESIQPTLSPGPITELQKGSDCCSCPKRWIGHQCNCYLFFDELKSWTESRDFCASQNSSLLHIQNRDELRFVSSSKYFYWIGVYYSKENGTWLWENGLALPQDLLQTIQTFDTKKCVIYSSSHSVLDVSCEDKSRFICKQELM",
    "output": "Immune receptor involved in self-nonself discrimination. In complex with KLRC1 or KLRC2 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule MHC-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia and non-classical MHC class Ib molecules. Enables cytotoxic cells to monitor the expression of MHC class I molecules in healthy cells and to tolerate self. Primarily functions as a ligand binding subunit as it lacks the capacity to signal.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSANQEEDKKPGDGGAHINLKVKGQDGNEVFFRIKRSTQLKKLMNAYCDRQSVDMNSIAFLFDGRRLRAEQTPDELDMEDGDEIDAMLHQTGGSGGGATA",
    "output": "Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Required for the massive protein sumoylation in the nucleus induced by heat shock and controlled by SIZ1. Involved in the regulation of the heat stress transcription factor HSFA2 in acquired thermotolerance."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MHIYILGSAAGGGFPQWNCNCPNCHGVRTGTINAKVRTQSSIAISENGVDWILLNASPDIRQQLFDFKAAQPARKLRDTGITNVILMDSQLDHTTGLLTLREGCPINVWCTEMVYQDLTTGFPVFNMLKHWNGGLLYHQIDPKQAFKIDGFENLEFLPLIIQSAAPPYSPHRHDPHEGDNIALIIKDHKTQKQLFYAPGLGKIDDQIMQIMQDSDCVMIDGTLWTDDEMQQTGVGKKTGREMGHLYISGEGGSLSYLNQLSTPKKVLIHINNTNPILNEDSAQFAELKANDVEVAFDGMQIEL",
    "output": "May be involved in the transport of PQQ or its precursor to the periplasm."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTRSLLWQMVIVLGAILMVNYVLTTLTPQTQEPVVDVSYSRFKTELAADNVAAITFEGNNVVGNLRERTILNRVEGTEEVQSFLRFRTTMPPVTDTRLLDDLEQRKVDVKVRPESKPSPWATAMIYMLPWLLIVGVWWFVIKGMRTRQGPGGGMMGGFSKSGAKMYTKERSRVTFADVAGLDEAKQELMEIIEFLRNPKKFMRLGAKAPRGVLLVGPPGTGKTLMARAVAGEAEVPFFTISASQFIEMFVGVGASRVRDLFNNAKKNAPSIIFIDELDAVGRSRGTGLGGGNDEREQTLNQLLSEMDGFEAHDEVIVMSATNRPDVLDPALLRPGRFDRQVTVERPDWRAREEILKVHTRQVPIDEDVDLQIIARSTPGMCGADLENLVNEAALIAARENAQKVTMQHFEQAKDRVLMGTERKLVMSQQEKRITAYHEAGHTLLARLSPGADPIHKVSIIPRGQALGVTQQLPVDDRYHYSRSYLMTRIAVSLGGRAAEKAIFEEYSTGAQNDLKQATDLAEKMVCQWGMSERVGPMSINRGEEHPFLGRKLASDNAFSQHMAWIIDQEIEKVVKAGEQAADEIIANHLPVLKKLADALLEEEVLDRTRVDEVLRETGIEVQDDPAAHPDGDHVLQGELAGGAVEG",
    "output": "Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MYRSHTCGELRAEHIGQEVLLAGWVHRRRDHGPLIFIDLRDRYGITQIVFDSADSPVAHAVASDARVEYVLQVRGRVVQRPEEAYNPDIATGMIEVHATEATVLNPAKTPPLYINKEGGEEETLRLKYRYLDLRRERMQRNIMLRHRIVKFIRDFLDREGFVEIETPILIKSTPEGARDYLVPSRLHPGKFYALPQSPQQLKQLLMVAGFDRYFQIARCFRDEDQRADRQPEFTQLDMEMSFVDQGDVLDIIERLFTALCREIVPHKRLVTPFPRLTYAEAMERFGSDKPDLRYGLELVDVSDVVAASSFGVFRAALDTGGQVKGLRIPGAGSYSRKQIDEVVELAKQAGARGLLWAVVPGEGGEVRSSFGRQVSPDEMAAIIRRMEGAPGDLLLIVADPPKIVAQTLDRLRREFGARLNLADPNVLAWAWVIDFPLVEWNEEEQRWDAVHHPFTAPKDEDLHLMDTDPGRVRAKAYDLILNGYEAGGGSIRIHRRDVQQRLFDLLGIDRETAMRQFGHMLEAFEYGAPPHGGIAPGIDRICMILADEVTIREVMAFPKTQQAVDLMTNAPSPVDERQLRELHIALRLD",
    "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MISDRKLEHLILCASCDVEYRKKTGFEDIEIVHRAIPEINKEKIDISLDFLGRELSSPVMISAITGGHPASMKINRELARAAEKLGIALGLGSQRAGVEHPELEGTYTIAREEAPSAMLIGNIGSSHIEYAERAVEMIDADALAVHLNPLQESIQPGGDVDSSGALESISAIVESVDVPVMVKETGAGICSEDAIELESCGVSAIDVAGAGGTSWAAVETYRADDRYLGELFWDWGIPTAASTVEVVESVSIPVIASGGIRSGIDAAKAISLGAEMVGIALPVLEAAGHGYREVIKVIEGFNEALRTAMYLAGAETLDDLKKSPVIITGHTGEWLNQRGFETKKYARRS",
    "output": "Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MWLQILSLVLSVGRIDAAPPGQSRIVGGYKCEKNSQPWQVAVINEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTKEPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP",
    "output": "This protein has both trypsin- and chymotrypsin-like activities, being able to release angiotensin II from angiotensin I or angiotensinogen."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAETQAPAGYLFSEKHEWVKVEGDTALIGISDFAQSALGDIVFVDLPKSGKTVKQFETFGTIESVKAAEDLYAPVGGEVIESNSALSKNPGDVNSKPFDSWMIKVKGFSTSELEKLLSPEKYKALVAKLE",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MYPSNKKKKVWREEKERLLKMTLEERRKEYIRDYVSLSTILSWKEEMKSKGQNDEENTQEAPQMKKSLSEKVSLYRGDITLLEVDAIVNAANASLLGGGGVDGCIHRAAGPCLLAECRNLNGCETGHAKITCGYDLPAKYVIHTVGPIARGHINGSHKEDLANCYQSSLKLVKENNLRSVAFPCISTGIYGFPNEPAAVIALGTIKEWLAKNHQEVDRIIFCVFLEVDFKIYKKKMNEFFPVDDNNEGTDADMKEDSEGPEPKGLSPPHKKSKAKKPESSKDSSEDESGPEEKQTAEEMEGQSQEAGGLRFLLRNLLGLIHRDGVNTTPVPSPASEDKAEVHKDEDSAKDDNTVKDSDMTNHSVCDQELPNGQENDSAKSEGKTEAESPSSSMETEDLSPNQEDAAIVEQPEVIPLIDDQEAQEGGEAQGKDAPAVFAESQGSSEAENTSGPDVDMNSQVDGVNEPTESLQEDLQ",
    "output": "Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNNQIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTDAIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRIDSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVKGQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLYLGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFNKQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNNYMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNYKTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLEKKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDPQLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSRLFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYLHNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSIGAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFIRESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESSSQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNYHPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQELQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVLASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDLSVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFRNYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLMLQQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTSIAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPVDNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSISSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVPLDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELSFDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNFLIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEASMEDLHPEIHALLQSAELLEEEAPDIPLRRVHSTSSLDSQKFVTVPSSNEVVTNLEVLTSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAAQDGEAMLRKILASQQPDRCKRAQAFISTQGLKPDTVAELVAEEVTRELLTSSQGTGHKQMFNPTEESQTFLQLTTLCQDRTLVGMKLLDKISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLQAAHMLTDNHLAPSEEYGLVVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAARIQLKLIESQPWEDSLKDGHQLKQLLLKALTLMLDAAESYAKDSCVRQAQHCQRLTKLITLQIHFLNTGQNTMLINLGRHKLMDCILALPRFYQASIVAEAYDFVPDWAEILYQQVILKGDFNYLEEFKQQRLLKSSIFEEISKKYKQHQPTDMVMENLKKLLTYCEDVYLYYKLAYEHKFYEIVNVLLKDPQTGCCLKDMLAG",
    "output": "May play a role in neurite plasticity by maintaining cytoskeleton stability and regulating synaptic vesicle transport."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNLKSPLFLRLSDRLDVYIRLMRADKPIGTLLLLWPTYWALWLASDGIPDLAVLAAFTIGTFLMRSAGCVINDFADRDFDGAVERTKNRPFAQGRVKKKEALLLTAFLCLLAALCLIPLNHLTWLMSLPALFLALTYPFTKRFFPIPQFYLGFAFSFGIPMAFAAVGNSVPVEAWILFAANVLWTLAYDTVYAMADKEDDLKIGIKTSAVTFGRYDIAAVMLCHGGFTLLMAVLGAVIGAAWAYWTAIPIVLLLQYRQYAAIKSRVRQICFETFLANNRIGWVWFAAIFAHTFFAK",
    "output": "Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVDYFDYNSLLTRAREQLPEEVFKDVRFEIPSADSFVEGNRTIIKNFKDIAKFMERDPQEFAKYVMKELGTAGDMEGVRLILQGKFGWRMVNEKIQNYVNEYVLCPECGKPDTKIVKEGRIHFLKCTACGAMKPVKTL",
    "output": "eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "SSTETPPSYNQLNYNENLLRFFNSKPVTAPVELDPPKVESSYVSSARGEDARSTLSPVQGFEGSGGSGSSGNFTTGSNLHMSSVTNTSNAGTGTSGTGNSGDGGGGGGADGPGSGAAPPVTLTESLLNKHNDEMEKFMLKKHRESRGRSGEKNKKSANDAMKMLEYSGPGPGHGHGIKRGGSHSWEGEANKPKQQLTLNTGGGGGGMPPFLDIQHTSSSTQNKGLAGVGVGGAGGGVVGVGSSAGGNGSGTGNNNGNGNNNQPTTNQFTQSGLSCTQNINLWPPFSVGITTPTSVLSSHTAVAQSSFSPQHSLFPTFYYIPASIAASSPSGTSPNPNRPHKHAHVHSSSEKPSTSQAAAATMPLQYMTGVMYPHPSLFYTHPAAAAATAMV",
    "output": "Essential for biological clock functions. Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms. Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system. The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex. Light induces the degradation of TIM, which promotes elimination of PER. Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop. Behaves as a negative element in circadian transcriptional loop. Does not appear to bind DNA, suggesting indirect transcriptional inhibition (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPRFVDRVVIHARAGSGGNGCASVHREKFKPLGGPDGGNGGRGGSIVFVVDPQVHTLLDFHFHPHISAPSGKQGMGNNRDGAAGADLEVKVPDGTVVLDENGRLLADLVGAGTRFEAAAGGRGGLGNAALASRARKAPGFALLGEPGETRELTLELKTVADVGLIGFPSAGKSSLVSAISAAKPKIADYPFTTLVPNLGVVSAGEHTFTVADVPGLIPGASAGRGLGLDFLRHIERCAVLVHVIDCATADPGRDPISDIDALEAELAAYTPTLQGDVTLGDLTERPRAVVLNKIDVPEARELAEFVRDEIAERGWPVFLVSTVAREGLQPLIFGLWQMISEYQSAQPEIVPRRPVIRPVPVDDSGFRVEPDPRQPGAFVVSGARPERWVRQTNFDNDEAVGYLADRLARLGVEEELLRLGARPGCAVTIGDMTFDWEPQTPAGQQVVLSGRGTDARLERTERVGAAERKAARRQRRTGDDAERGTTERGENT",
    "output": "An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDTEYEQVNKPWNELYQETTLGNQLMVNVGMEDPEVPLLPSNFLTKVRVGLSGGYITMRRIRIKIIPLVSRKAGVSGKLYLRDISDTTGRKLHCTESLDLGREIRLTMQHLDFSVSTRSDVPIVFGFEELVSPFLEGRELFSISVRWQFGLSKNCYSLPQSKWKVMYQEDALNVKPSKKKASKTDSSV",
    "output": "Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMETLPYLQCRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP",
    "output": "ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins . Functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which maintains these client proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation . The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum . Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated by RNF126, an E3 ubiquitin-protein ligase associated with BAG6 and are sorted to the proteasome . SGTA which prevents the recruitment of RNF126 to BAG6 may negatively regulate the ubiquitination and the proteasomal degradation of client proteins . Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum . The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome . BAG6 is also required for selective ubiquitin-mediated degradation of defective nascent chain polypeptides by the proteasome. In this context, it may participate in the production of antigenic peptides and play a role in antigen presentation in immune response (By similarity). BAG6 is also involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation. BAG6 may ensure the proper degradation of these proteins and thereby protects the endoplasmic reticulum from protein overload upon stress . By inhibiting the polyubiquitination and subsequent proteasomal degradation of HSPA2 it may also play a role in the assembly of the synaptonemal complex during spermatogenesis (By similarity). Also positively regulates apoptosis by interacting with and stabilizing the proapoptotic factor AIFM1 (By similarity). By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway .; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIDKYSSNLVPVNIEDEMKVSYLDYAMSVIVSRAIPDVRDGLKPVHRRIIYSMYEAGNHASKPYRKSARIVGDVMGKYHPHGDSAIYDSLVRMAQDFSLRLPLVDGQGNFGSMDGDAAAAMRYTESRMAKVAHKLVEDIDKGTVSFNINYDGSEEEPSVLPAMFPNLLVNGSGGIAVGMATNIPPHNLGEIIDACCLYIDNHDIEILDLLEVVKGPDFPTGSMILGISGIRSAYLTGRGSIIMRGKAEIENVGNSRQAIIITEIPYMVNKARLVEKIAEMVKEKRIEGISDLRDESNKNGIRIFIELKKDVVAEVVLNQIYACTQLQTNFGVIMLALKDGLPKVMNLKEVIAAFVSFREVVITNRTIYLLNKARDRAHILLGLTIAISNIDEIIYIIKASNDTNLAKQELMARQWEVLDILPLIKLVDDKVILNERGTLSFTEVQAKAILEMKLQRLTAMEKEKLEQDLKHLATDIAEYLNILASRTRLLEILKEELIKVKEEFASPRLTSIEFGEFDQDIEDLIQREEMVVTVTLGGYIKRVPLSSYRSQKRGGKGRSGLSMRDEDITTQVFVGSTHTPMLFFSNIGKVYSLKLYKLPLSNPQGKGRPMVNILSLQENEHITNIMPLPENQDEWDHLNIMFATAKGNIRRSDLLDFKKIQSNGKIAIRLDEDDKLIDVKPCKEDEHILLATKAGKALRFPVESLRIIKSRISDGVRGMKLAKEDSVISMTVLKGINSTKEDRDAYLTVPWEKRLEIAKGEEFNLEELGVNLNADSILEMANSEEFILTVTENGFGKRSSAYGYRITDRGGSGIINMDINDKTGLVVGVMPVKMDDELMLITNSGKLIRCKLESVRITGRNTSGVILFKLDDDEKVVSVSLIAETSESEEASELAEEGLENDVKV",
    "output": "A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTDLIAKTAIDRRLAEIISPVIEDLGFELVRIRLQGGKTATLQIMADRPEGGINVDDCADISTAVSAILDVEDPLEDAYHLEVSSPGIDRPLTRLKDFETFEGYEARLETNQPIDGRKRFKGVLAGVEKGEGGDEVLLNIEEGGETQTIGLNFDWLSDAKLVLTDELIAEMLRQKKDAGVQIENLDEAAFDEIETEAGEDNAAAKE",
    "output": "Required for maturation of 30S ribosomal subunits."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKELTAKKRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHNHLETCFSTAVLDGHGQAAIEELIDAVKFTPALTGPHARLGGAAVGESATEEPMPDASNM",
    "output": "Copper-sensitive repressor that has a key role in copper homeostasis. It is part of the cso operon involved in the cellular response to increasing concentrations of copper inside the bacterium, which can be highly toxic. In the presence of copper, CsoR fully dissociates from the promoter in the cso operon, leading to the transcription of its genes. Binds to a GC-rich pseudopallindromic sequence, 5'-GTAGCCCACCCCCAGTGGGGTGGGA-3', in the cso promoter region."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAEPGFFNAMLIGALIFGYVLGSIPFGLILTRLAGLGDVRAIGSGNIGATNVLRTGNKKLAAATLILDALKGTAAALIAAHFGQNAAIAAGFGAFIGHLFPVWIGFKGGKGVATYLGVLIGLAWAGALVFAAAWIVTALLTRYSSLSALVASLVVPIALYSRGNQALAALFAIMTVIVFIKHRANISRLLNGTESKIGAKG",
    "output": "Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFRIVNGEDYSPAVQQRNILDFGKAPSLLWTDNGSSNDRCDTGGNCRESGQDRVKRPMNAFIVWSRDQRRKVALENPQMQNSEISKRLGYDWKMLTEAEKQPFFEEAQRLRAMHRDKYPGYKYRPRRKAKEATEIASRRLFSTVQPNAHRGDLVPLHIQGHTFTNGKPVKPLTAHEHKQLTPATGASQQSDKPAPQ",
    "output": "Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIRIAIDVMGGDFGPDVAIPGAAKALERHNDVTFLLYGQKSKCDPILAQYPALREKSVFHDCEVSVSMDEKPSQALRRGRYVSSMWRAIEAVKLGEADVAVSAGNTGALMAMAKFCLRTMARVERPAIAGIWPTLKGESIVLDVGATIGADSQQLLDFALMGGAMARALFDIDRPTVGLLNVGVEEVKGQEEVREAGRLIREADLGTIDYRGFVEGDDIGKGTVDVVVTEGFTGNIALKAAEGTARQITTLLREAISRSFFAKIGYILAKSAFDVLREKMDPRKVNGGVFLGLNGIVIKSHGGTDAIGFASAVDVGYDMVHNGLTAKIENDLKIYHARRLPPPAPEALVADEE",
    "output": "Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTIAVDLQGRPFHFIGIGGIGMSALAQVVTERQLPVSGSDIRRSHITDRLAQLGAQIFDRQAATNLEFFQEAVSAGQSPQVICSTAIHAHNEEYQAAIDLGCPVFHRSDLLAALLRVYESIAVAGTHGKTTTSGLIAYLLYQAGLDPTVVIGGEVNALGGNARLGQGRHLVAEADESDGSLVKLQAAIGIITNIELDHPDHYCDLEAVISTFKTFSDNCSQLIANWDCPTVRDRLPGTISYSLDPARGADYTVDQVSFRGSGTQARIWERGELLGRIHLPLLEAHNLSNALAAIAACRHLGMDFASIREGLAGFEGARRRFEFRGSAQGIQFVDDYAHHPSELAATLAAARLQIDSGCSRLPEVPKRLVAIFQPHRYSRTQAFLAEFAQSFGPADLVLISDIYAAGERNPGQLSGQTLADAIAQYQANVHYAPDLEAVEQRLHQLLQPGDLALFLGAGNLNQVIPRLLDHYACDRSAA",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDIGAEQRRQLEERLVLQLRMIAKGAYYWYRREQEKIAHHSE",
    "output": "Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEKFMAEFGQGYVQTPFLSESNSVRYKISIAGSCPLSTAGPSYVKFQDNPVGSQTFSAGLHLRVFDPSTGALVDSKSYAFSTSNDTTSAAFVSFMNSLTNNRIVAILTSGKVNFPPEVVSWLRTAGTSAFPSDSILSRFDVSYAAFYTSSKRAIALEHVKLSNRKSTDDYQTILDVVFDSLEDVGATGFPRGTYESVEQFMSAVGGTNDEIARLPTSAAISKLSDYNLIPGDVLYLKAQLYADADLLALGTTNISIRFYNASNGYISSTQAEFTGQAGSWELKEDYVVVPENAVGFTIYAQRTAQAGQGGMRNLSFSEVSRNGGISKPAEFGVNGIRVNYICESASPPDIMVLPTQASSKTGKVFGQEFREV",
    "output": "Structural component of the distal-half of the long-tail fiber. The long-tail fiber of T4 is about 1600 Angstroms long with a kink in the middle that divides the fiber into proximal and distal halves. The latter hinge is probably composed of gp35 protein."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTQKNGPLRVGIGGPVGSGKTTLTEKLCKAMRDKYSVAVITNDIYTQEDALILARRQALSEDRIIGVETGGCPHTAIREDASINLQAVVEMTRRFPDLDVVFIESGGDNLAATFSPDLADLTLYVISVCQGEEIPRKGGPGITRSDFLVINKSDLAPYVHVDLEVMEADAMRMRAKRPFGFTDLHRGKGVQEIIDFIVENGGLEPRSN",
    "output": "Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK",
    "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAHLLLLHGPNLNLLGTREPEVYGRTTLAQIDAALVDRAQAAGHALDCLQSNAEHVLVERIHAAREDGTAYILINPAAFTHTSLALRDALLGVGLPFVEIHLSNPHAREPFRHHSYLSDKADGVICGFGADSYRLALEAVIARLECDA",
    "output": "Catalyzes a trans-dehydration via an enolate intermediate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSYRRELEKYRDLDEDEILGGLTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFRREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPMDPVLESVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKEGLNSVIKPTQYKPVPDEEPNATDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILRLVEALPYNTSLVELKIDNQSQPLGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGV",
    "output": "Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKSLDDLDFDNRFARLGDAFSTEVLPDPIAEPRLVVASPAALALLDLPAETSDEALFAELFGGHKLWSEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVINQAGEHWDLHLKGAGQTPYSRMGDGRAVLRSSIREFLASEALPALGIPSSRALCVIGSSTPVWREKKESAATLLRLAPSHVRFGHFEYFYYTRQHDQLKQLAAFVQEHHFADCNAAERPYAAMFRQVVERNAELIARWQAYGFCHGVMNTDNMSILGITFDYGPYAFLDDFDANHICNHSDDAGRYSFSNQVPIAHWNLAALAQALTPLVEVDELRASLDLFLPLYQAHYLDLMRRRLGLGVAAENDQALVQELLQRMQGSAVDYSLFFRRLGEETPERALASLRDDFVDREAFDRWAEAYRRRVEEEGGDQESRRRRMHAVNPLYVLRNYLAQQAIEAAEQGDYTEVRLLHQVLSRPFEEQPGMERFTRRPPDWGRHLEISCSS",
    "output": "Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGGKTVTRADLAEAVYRKVGLSRTESAALVEMILDEVCDAIVNGETVKLSSFATFQVRDKNERIGRNPKTGEEVPILPRRVMTFKASNVLKQRILQEHQKRQGKTSK",
    "output": "This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLTERQLLIFRAIIDHFTWTIQPVGSKNLLKEKSLPYSSATIRNEMGVLEEYGFIEKTHSSSGRVPSEKGYRFYVDYLLQPKKLDKSDRQMIRSFFSENYYEMEGLIQNSALMLSDLTNYTSILLGPEATKNHLSGFRFVPINNFQAMLILITDQGHVDNHLVTIPEGTTLSDIERMVNILNERLVGLSLDDLKVQIPMEVKELLGKHVRNYESFMHVFSDSFAQASQQKVYFGGKTNILNQPEFHDINKVREMLHLMEEEQDVYELFRDIPDGLQVKIGRENNNSLMEDCSIITATYNIAGERVGGIVLLGPTRMEYSRMMGLVDVMSRDLTDVLTKLYRDNQN",
    "output": "Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPTVFPDDSVGLVSPQTLHFNEPLELTSGKSLAEYDLVIETYGELNATQSNAVLICHALSGHHHAAGYHSVDERKPGWWDSCIGPGKPIDTRKFFVVALNNLGGCNGSSGPASINPATGKVYGADFPMVTVEDWVHSQARLADRLGIRQWAAVVGGSLGGMQALQWTISYPERVRHCLCIASAPKLSAQNIAFNEVARQATLSDPEFLGGYFQEQGVIPKRGLKLARMVGHITYLSDDAMGAKFGRVLKTEKLNYDLHSVEFQVESYLRYQGEEFSTRFDANTYLLMTKALDYFDPAAAHGDDLVRTLEGVEADFCLMSFTTDWRFSPARSREIVDALIAAKKNVSYLEIDAPQGHDAFLMPIPRYLQAFSGYMNRISV",
    "output": "Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNEFDRVRDYLTDLQDRICAAVEAADGKARFAEDLWKREEGGGGRTRILRDGAVFEQAGIGFSDVSGTRLPPSASAHRPELAGATWRACGVSLVFHPHNPYIPTTHMNVRYFRAERDGEVVAAWFGGGFDLTPFYPFDEDVQHWHRVAQALCVPFGQERYAAHKRWCDEYFFLRHRNETRGVGGLFFDDLGQDFERDFAYQRAVGDGFLDAYIPIVQRRKDTPYGEREREFQLYRRGRYVEFNLVYDRGTLFGLQSGGRAESILMSLPPRVRWEYGFTPEPGSAEARLADYLIPRDWLG",
    "output": "Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATASQGKVTQVIGAVVDVQFDGGLPPILNALETENNGKRLVLEVAQHLGESTVRTIAMDATEGLVRGARVTDTGSPISVPVGDATLGRILNVIGEPIDEKGDLGEASTRAIHQPAPTFAEQSTTSEILVTGIKVIDLLAPYSKGGKIGLFGGAGVGKTVLIMELINNIAKVHSGYSVFAGVGERTREGNDLYHEMIESGVIKIDNLSESKVALVYGQMNEPPGARARVALTGLTLAEQFRDQSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITSTKAGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRAISELGIYPAVDPLDSTSRILDPQIVGEEHYNVARAVQGILQRYKSLQDIIAILGMDELSEEDKLSVARARKIQRFLSQPFDVAKVFTGSDGVQVPLEKTIASFKAVVNGEYDHLPEAAFYMVGDIEDVIAKAQRLAAQAA",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKHTAEFLDTHQTQISSILSGGYNHPLLREWQNERQLAKNMFIFPLFVSDMPDEDQPIESLPNIRRFGVNKLAGYLKPLVAKGLRAVLLFGVPMKPNSKDEFGSAADDPEGPVIQAIKLLRAEFPELYILCDVCLCEYTSHGHCGVLYDDGSINREQSVRRLAAVAVNYAKAGAHSVAPSDMIDGRIRDIKLGLLAAGLAHKTFVMSYAAKFSGNLYGPFRDAACSAPSQGDRKCYQLPSGGRGLARRALRRDLDEGADGIIVKPSTFYLDIMADASEIAKDVPICAYHVSGEYAMLHAAAKAGVVDFKSIAFESHQGFLRAGARLIISYMTPEFLDWLS",
    "output": "Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAIPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAAVGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTKRKNLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD",
    "output": "Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAATLRELRGRIRSAGSIKKITKAQELIATSRIAKAQARVEAARPYSTEITSMLTELASASALDHPLLVARENPRRAAVLVVSSDRGLCGAYNANVLRQSEELFALLREEGKEPVVYTVGRKAQGYFNFRQREVTESWSGFSERPTYENAKEIADTLVASFMSGADDEGDDAGADGVLGVDELHIVFTEFRSMLSQSAAARRIAPMVVEYVGDEQPEDGPQTLFSFEPDPETLFDALLPRYVATRVYAALLEAAASESASRRRAMKSATDNADDLIKALKLSANRERQAQITQEISEIVGGANALADSR",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MINIPTSILCRLGARSAISRSFGTSVVTKSEAKTPIQKFGWEYLKKQRDMKRPIAPHLTIYQPQLTWMLSGFHRISGCVMAGTLLVGGLGFAVLPLDFTTFVEYIRGWNLPCAVTAVFKYIIAFPIIFHTLNGIRFLGFDLAKGVDNIGQVYKSGWLVFGVSAVIALAIVINSCQNKSKAVKTA",
    "output": "Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Mediates resistance to enteropathogenic E.coli infection (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTKTKQEIYNKRPTSPHLSIYKLQISSTLSILHRMTGVALFFAVSILAWWLILSKYDNNYLQFANCCIIKICLVAVSYAWFYHLCNGIRHLFWDIGYGFSIKAVNITGWCVVVCSILLTMLLWV",
    "output": "Membrane-anchoring subunit of succinate dehydrogenase (SDH)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MALPLDFEKPLFELETKIDELRTFSQEKDLDFSSEIATLEQKAEELRKKIYRDLTPWQQAQLARHPDRPNTIEYIRLLFEEFYEMKGDRLYGDDPAIVGGIARFQGRPVTVIGHVKGKDTKENIYRNFGMPHPEGYRKALRLMRQAAKFSRPIICFIDTPGAYCGIGAEERGQAEAIARNLLEMAALPVPIISVIIGEGGSGGALALGVADRLLMLEHAVYSVASPESAASILFKDASLAPQAAAAMGITAERLKDLKLIDRIVPEPSGGAHRNPIGTAKELATALSEEIENLLALSAQELVDSRYAKYRNLGLHCIEDASCGTFEAEATDASGT",
    "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSIRIKLKPGREKSLDRRHPWVFSSGVHNIKGKPLRGETVDVVAHDGRWLGRGAWSDASQIQVRVWTFDKEEAIDRDFFARRIARAQAGREALIREKGLTGYRLVGAESDGLPGITIDRYANVLVCQLLSAGADYWRETLVSVLAEQFPECAIYERSDVDSRKKEGLPLVTGLLHGELPAMPLIIEENGIKIAVDVEKGHKTGFYLDQRDNRAMAGRFVEGKSVLNCFCYTGTFGLYAAKAGAASIENVDVSTLALDTARHNMAINGLNDDHVTYSEADVFKLLRQYRDEGKTFDVIVLDPPKFADNKAQLNGACRGYKDINMIAMQLLKPGGTLLTFSCSGLMPADLFQKIVADAALDAGRDAQFIERLSQASDHPIGAAFPEGFYLKGLVARVW",
    "output": "Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSEDLSKLHTSRMNKLQRKLRGEVGKAIGDYNMIEEGDRVMCCLSGGKDSYAMLDILLNLQQRAPIKFEIVAVNLDQKQPGFPEEVLPAYLDTLNVPYHIIEKDTYSVVREKIPEGQKTCSLCSRLRRGTLYGFAQKIGATKIALGHHRDDIIETLFLNMFFAGKQKAMPPKLLSDDGANMVIRPLAYSREKDIAEYAELKAFPIIPCNLCGSQENLKRAEVKDMLNLWDEHHPGRIESIFTAMQNTSPSQGVDREQFDFNSLQRDADAPLRGDVAESDLPAFDFVDVANNGHIDLDAAAKSRSENKIDIVSTYTP",
    "output": "Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAANMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYKDEHPNDDSSRRWLFYWQHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRGRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKPNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL",
    "output": "Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSTTPVVNFITGNANKLREVKAILEPGITVQSKTVNLEEVQGTVEEVTLAKCRKAAEIIQGPVLVEDTCLCFKALNDLPGPYIKWFMESIGHQGLNNLLVAYEDKSADAVCTFAYSPGPGHEPILFQGRTRGKIVPPRGPADFGWDAIFEYDGQTYAEMDKTAKNNISHRGLALRKLQDWFAQQ",
    "output": "Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIHFTKMHGLGNDFMVVDGVTQNVFFSPEQIRRLADRNFGIGFDQLLLVEPPYDPDLDFHYRIFNADGSEVEQCGNGARCFARFVRNKGLTQKNKIRVSTNSGKITLRIERDGNVTVNMGVPVIEPSQIPFKAKKSEKTYLLQTPMQTYLCGAISMGNPHCVIQVEDVQTVNVDEIGSSLTRHERFPKGVNVGFMQVINPGHIKLRVYERGAAETLACGTGACAAAAVGQLQDKLDKQVRVDLPGGSLIINWEGEGKPLWMTGPAEHVYDGQIQL",
    "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDSPCQPQALNQALPQLPGSVSESLESSRARMGVESYLPCPLLPAYHRPGASGEASAGNGTPRTTATATTTTASPLREGFGGQDGGELWPLQSEGAAALVTKECQRLAAQGARPEAPKRKWAKDGGDAPSPSKRPWARQENQEAKGESGMGCDSGASNSSSSSSNTTSSSGEASARLREEVQPSAPERLALDYIVPCMRYYGICVKDNFLGAVLGGRVLAEVEALKWGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGNYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAARDKYQLASGQKGVQVPVSQPTTPT",
    "output": "Prolyl hydroxylase that mediates hydroxylation of proline residues in target proteins, such as ATF4, IKBKB, CEP192 and HIF1A . Target proteins are preferentially recognized via a LXXLAP motif (By similarity). Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins . Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A . Also hydroxylates HIF2A . Has a preference for the CODD site for both HIF1A and HIF2A . Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex . Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes . EGLN2 is involved in regulating hypoxia tolerance and apoptosis in cardiac and skeletal muscle . Also regulates susceptibility to normoxic oxidative neuronal death . Links oxygen sensing to cell cycle and primary cilia formation by hydroxylating the critical centrosome component CEP192 which promotes its ubiquitination and subsequent proteasomal degradation (By similarity). Hydroxylates IKBKB, mediating NF-kappa-B activation in hypoxic conditions (By similarity). Also mediates hydroxylation of ATF4, leading to decreased protein stability of ATF4 ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNLLEHMGKAAKQASWQLAMLSTAKKNQALAVIANLLESESQTILQANERDMAAARESGMSEALLDRLLLTPARLAAIANDVRQVCRLNDPVGRVIDGSLLDSGLKLERRRVPLGVIGVIYEARPNVTIDVASLCLKTGNAVILRGGKETHHTNQATVNVIQRALEQCGLPAAAVQAIESPDRQLVNELLRLDRYVDMLIPRGGASLHKLCREQSTIPVITGGIGVCHTFVDENADFEKALLVIENAKIQRPSACNSLETLLVHQAVAKTFLPLLSARMHAFGVTLHASPLAMPYLADGKAKVVAVEAADYDDEWLSLDLNVDIVTDIDAAIDHIREHGTSHSDAILTRSLSHAEYFVRAVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLDALTTYKWIGYGDDLVRS",
    "output": "Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTKQSIRAREFKRIILAKKFFAKRIKLKQIISNIHSSSEERWNAIIKLQQLPRDSSRSRQRNRCSQTGRPHAFLRKFGLSRIKVREAAMRGEIPGLRKASW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSTGNVYQELIRRYLVVVKKLYEEPIPQTARQRRRRKQQLRTRRAQLRELEGRILKQILDRGPDQLCQGVTNLALAEKSESSN",
    "output": "Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts). This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MALETNTHRSYSIIPCFIFVELVIMAGTVLLSYYFECTDTFQVHIQGFFCQDGNLMKPYPGTEDESFISPLVLYCVLAATPTAIIFIGEVTTYFIKSTRENLIVQEKMILTGECCYLNPLFRRIIRFIGVFAFGLFATDIFVNAGQVVTGNLTPYFLTVCKPNYTASDCLIYHQFINSANICTGDPEVIEKARRSFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPVLCLGTLCCAFLTGLNRVSEYRNHCVDVIGGFILGTAIALFLGLCVVHNFKGLYGAQCKPKPEDPRGVPLMAFPRVESPLETLSAQNHSSSMTEVT",
    "output": "May play a role in neurite outgrowth and neurogenesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKNKILVKNNELTVDISAFDDKDEVLSLQRKNFNLILGKDSFLRGFDANLIGQKSLPLYEFSMVIPSDFKDEKLRGKTLDFKVHNKAKIKVNSETNLDKEKIKSLEKELANQKEKNALLLLDNVKLKSEKEKIIKDFKDEIKTFENRAREKIAEKLNLEKQLLENKFEDFKKYGSQKIFESIMPIIQNLLVAIE",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDPAPTLAAELWRTPYLGGGGGGGGGGRGLEAAASGVTEQSNGSRGGGGGGGAGRRRQREAPALEDDSSRIVSTSGGGGGGQDLTDSEAKRFKASKSSGDNSSLRTEAETDSRNASKSGDQNPPPPEPPKQDYIHVRARRGQATDSHSLAERARREKISERMKILQDLVPGCNKVIGKASVLDEIINYIQALQRQVEFLSMKLEAVNAHVNNGIEAFPPKDFGAQVYNTAPGLTFDPQTPREYAQGSTPSEWLHMQIGGTYERVT",
    "output": "Transcription factor that may regulate jasmonate-regulated genes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPDLNESRAFDQIDNAPEERQRGITINISHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDEELLELVEMEVRELLAAQEFDEDAPVVRVSALKALEGDAKWVESVEQLMEAVDESIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGIRPSSTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVTKPGTTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNTNISVKLIQPVAMDEGLRFAIREGGRTVGAGRVVKIIK",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSNKKRSASSSRWLQEHFSDKYVIQAQKKGLRSRAWFKLDEIQQSDKLFKQGMTVVDLGAAPGGWSQYAVTQIGSKGRVIACDLLPMDPIVGVDFLQGDFRDELVLKALLERVGDKKVQVVMCDMAPNMSGTPAVDIPKSMYLVELALDMCRDVLAPGGSFLVKVFQGDGFDEYLREIRSLFTKVKIRKPDASRARSREVYIVATGRKL",
    "output": "Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAITKEDILEAVGSLTVMELNDLVKAFEEKFGVSAAAVAVAGPAGAGAADAEEKTEFDVVLASAGDQKVGVIKVVRAITGLGLKEAKDIVDGAPKTIKEGVSKAEAEDIQKQLEEAGAKVEIK",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPMTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIQAVAIGMTSASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFAFTKMITKVRSKILVSLMFCLASAFLSAFLDALTVIAVIITVAVGFYSIYHKVASGKDFSADHDHTSEGKNEDGENQLNEEELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQFGEFAIRMSPVTVPVLFAGILTCFLVEKLRWFGYGAQLPEAVHKILCDYAAYEDARRTNKDKMKLVIQAFVGVWLIAGLALHLASVGLIGLSVIILTTAFNGITDEHALGKAFEEALPFTALLAVFFAVVAVIIDQQLFGPVIQWALNHEGNTQLVIFYIANGLLSMVSDNVFVGTVYINEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTIVLSIVGVMAIESGFLEQMTQYFYDSHAIIHHSVKEALAPAAAH",
    "output": "Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAPSSAHNNGFYVLMLVGIVVSTMVATCAGSFYQDFDLTWGGDRAKIFNGGQLLSLSLDKVSGSGFKSKKEYLFGRIDMQLKLVAGNSAGTVTAYYLSSQGPTHDEIDFEFLGNLSGDPYILHTNIFTQGKGNREQQFYLWFDPTRNFHTYSIIWKPQHIIFLVDNTPIRVFKNAEPLGVPFPKNQPMRIYSSLWNADDWATRGGLVKTDWSKAPFTAYYRNFKAIEFSSKSSISNSGAEYEANELDAYSRRRLRWVQKYFMIYNYCSDLKRFPQGLPAECKR",
    "output": "Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLSKRILPCLDVKAGRVVKGVNFVDLKDAGDPVELAKVYNDAGADELVFLDITATHEDRDTIIDVVYRTAEQVFIPLTVGGGIQSLENVKALLRAGADKVSINSAAVRDPELIDRASDRFGNQCIVVAIDARRRVDPSNPGWDVYVRGGRENTGLDALSWAKEVEKRGAGELLVTSMDADGTQAGYDLELTRAIAESVEIPVIASGGAGNCEHIYTALTEGKAEAALLASLLHYGQLSVAEIKNYLRDCQVPVRLYA",
    "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKLRPYYEESQSAYDISDDFFALFLDPTWVYTCAYFERDDMTLEEAQLAKVDLALDKLNLEPGMTLLDVGCGWGGALVRAVEKYDVNVIGLTLSRNHYERSKDRLAAIGTQRRAEARLQGWEEFEENVDRIVSFEAFDAFKKERYLTFFERSYDILPDDGRMLLHSLFTYDRRWLHEQGIALTMSDLRFLKFLRESIFPGGELPSEPDIVDNAQAAGFTIEHVQLLQQHYARTLDAWAANLQAARERAIAVQSEEVYNNFMHYLTGCAERFRRGLINVAQFTMTK",
    "output": "Involved in the conversion of a cis-olefin into a trans-olefin with concomitant introduction of an allylic methyl branch at the proximal position of the precursor to both the methoxy and ketomycolic acids. It directly affects the cis- to trans ratio and indirectly affects the keto to methoxy ratio."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGKSLADKQELVAEIKDLLKDAQLTFVIDYKGLTVAEITDLRNRLRPAGAYCKIAKNTLMHIAVDGDETWQPVQSLLKDSSAFLIAGEDVASAVKAYKEFRKATKKTELRGGVMEGQALTSDQIEALGDLPTKDQLYGQIAGAINAVTAKIAIGINEVPGSLARAIKAVSEKEAA",
    "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTELVLIMVSAILVNNFVLVQFLGLCPFMGVSKKIETAIGLSLATTFVLTLAAMCSYLVQQYVLKPLDLEFLRTISFILVIAVTVQFTEMVVNKTSPLLYRVLGIFLPLITTNCIVLGVALLNANKAEFTFITATVNGFAAGLGFSLVLVLFAAMRERIAIADVPKSFQGAAIGMITAGLMSLAFMGFAGLIKL",
    "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKVSIFKTLYFQVLTAITIGVLLGHFYPEIGAQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAIALLYFEIVSTLALLIGLVVVNVAQPGVGMNIDPATLDAKAVALYAEQASQQGIIPFLLDIIPGSVVGAFASGNILQVLLFAVLFGFALHRLGEKGQLIFNVIESFSRVIFGVINMIMRLAPLGAFGAMAFTIGKYGVGSLVQLGQLILCFYLTCILFVVLVLGTIAKFNGFNIFKFIRYIKEELLIVLGTSSSESVLPRMLDKMENAGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTHMDIMHQVTLLVVLLLSSKGAAGVTGSGFIVLAATISAVGHLPLAGLALILGIDRFMSEARALTNLVGNGVATIVVAKWCKQLDNDQLQAVLSNKVLPNVKSSVSVS",
    "output": "Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARKPGRPGGNRVVNMLKRTAANAASPLGLAKRLLGDAFAGRGPLRVILAVVAFFRFTAIKMSPALLKKWGTVEKGAAIAIMKSFKKEIGSMLDVVARRKTKNKGKRSVESSALLVLLTACLALGFKVVTGPEGPIMDVTKKDVGKALEIPFQNFNNTCWVMAMDVGHPCEDTIEYECPSLDIGAEPNDIDCWCDTMPMRVRYGRCTKGSIPKRSRRNAVFPQHTENVLATRQETWMNTDVIMKHLIKVETWALRNPGFALVAITLGWMLGSNRSQKIIFTILLLLVAPAYNMRCIGVENRDFVEGLSGGTWVDVVLEHGGCVTVRVEGKPTLDFELVQTKATGLAAVRAYCYQAKVSDIQISAACPAVQLTENSKATDSNYLCRRGVTNRGWNNGCGLFGKGDIHTCVKFKCEKKAAGFSIGKENLEYEVRASVHNSIGADKFSNELADGEPHTQKMKFSPLSPSAEKSFGDYGTLGMDCEPQSGLDFGQLYLMTIESKSWLVNRDWYHDLHLPYTVGSGSQWNNREALVEFQEPHATKQEVLALGSQEGALHSALAGAIMANRETSSPHALLLTAGHLKCRIKMDKMVIKGITYGQCSGTFKMEKHPADTGHGTVVLDVSYQGDDAPCKIPIVITSNLAEVEPVGRLVSAHPVITAKNVRTMLEVEPPYGDSYIVIGVGDGRLKQHWFKKGSVIGGAFSTTMKGAKRLAVLGDAAWDFGSVGGVFNSLGKAVHQLFGGIFRTLFGGMSWLSRLMIGALCLWIGINARDHSIAVTMLSVGGILIFLSINVSADTGCVVDIERKELKCGSGIFIMNDIEAWRDEYAFHPSGPKALAASVVEAFSQGVCGVRSVNRLEHKMWESIADELNAILEENEREITIVVKDMENPAQKGKMRLRPVEKELKYGWKKWGASFFKRASRKNATFLVDGPSGEECPNSNRAWNSFFIEDFGFGVFKTSVWLGLNEQMTEVCDTKMIGTGVKNDRAVHSDLGYWIESRKNLTWEISRARLIETKACIWPRSHTLWSDGIEETQLIIPKSLGGPRSRHNMRSGYKTQINGPWDQIPLDIKFEECPGTSVTVTPNCGGRGPSARSTTASGKVIADWCCRDCILPPLTFRSGETCWYAMEIRPVSEREETLIRSKVSAGDGNEIDTFSLGLLVAMLVTQEGLRKRWATRHIMVASLTMLAAMVTGHITYRDLLRYVVLLGATFAQINDGGDVMHLALVAVFKVQPGFLLGFLLRRRWTPRESMLLAISACFLHLVFSELSTDITTLAHNFSLALLILRAIIQTDVSSVTLPVLSMMAPSFQLSVLGTFRMAVAVYVIVNLMMSKRNDAVKKAAPSVVAAALGQFGMVNATAALGTLYVLEKHGKRSWPPSEIFSAVGVLCALVGALGNVQSTPLAGPMAACGLLIAAYVVTGKSTDIEIERAGLISWSEDAEVSGSSPRVDVALDENGDFSLIDGQGPSLESVILKTALVAFSGLFPVSIPFCAAAWYLHGKSGRRAGALWDIPAPREVKKGSTENGVYRILANRLFGKTQVGVGVMHEGVFHTMWHVTRGAALKSGEGRLDPYWGDVKKDLISYGGPWKLEGRWDGVSEVQLIAVPPKEKAKNVQTTPGVFKTPHGEIGAIVLDFPAGSSGSPIINKLGEVIGLYGNGLMMGDAYASSIAQAEVEDEPDTPNCLPPDVTHKKKLTVLDLHPGAGKTRKVLPKLLQEALEKRLRTVVLAPTRVVAAEMAEALKGMPIRYQTAAVTSSHSGNEIIDLMCHATFTSRLMQPHRVPNYNLYIMDEAHFTDPASIAARGFIATKVSLGEAAAVFMTATPPGSDNPFPASNAPITDTEAQIPDKAWSTGFDWITEYGGKTVWFVPSVRMGNEIAACLTKAKKKVIQLSRRTFNTEYPKCKQGDWDFVVTTDISEMGANFKATRVIDSRRAIKPSIMQDQEERVVLSGPTPISPASAAQRRGRVGRNPNQLGDEYVFSGLTQANDEGNACWTEARMLLDNIHMQNGLIAQLYGPEQDKCFATDGEFKLREKERATFLEFLKADLPVWLSFKAASSGVQYHDRKWCFDGPDNNLVLEDNVPVEIWTKSGERKKLKPRWSDARTYCDHGALTAFKEFAGGRRSVTTGLLEGVGRLPEHLGQRLKESIDTLYLAFTAEVGSRPHREAMQEMPAALETVLVFFLLMIMTGCTFFLLMRHKGINKMGYGMVVMSAVGGLLWYGNVPAPKIAGILLLTFLLMVVLIPNPEKQRSIQDNQLALVVLGCLMFLGGIAANEMGMLERTKQDLAGVFHKTERKSTEFTLLTPPDLRPATAWSIYAIGTTLITPLIHHMITTHYANFSLMAMANQAGSLFGMQTGAPFSKMDWAVPAIVVGCWQQLTPATLMTALVLLAVHYIYMIPGWQAGAARAAQRRTAAGIMKNPVVDGLVVTDIPTLEEVDPLVEKKLGQYILLAVAIAAAVLRQDLQSWSECATLSAAAAATLWEGSPGKIWNASTACSLVNIFRGHTLAAVPFMFTILRNTGNTGKRGGVEGETLGEKWKHLLNAMDKYEFSRYKVNGIFEVDREPARMALANGLVTSGHAVSRGSAKLRWMVERAAVRPTGRVIDLGCGRGGWSYYCATLKQVQEVRGYTKGGPGHEEPRMVQSYGWNIVTLKSGVDVFHRPAEVGDTILCDIGESSATPEVEEARTLKVLEMVEPWLKNKPEFCIKVLCPYRPKVIERLSALQRTYGGGLVRVPLSRNSTHEMYWTSGTAGNIINAVNLTSKVLLHRMEKKWIGPRYEKDVNLGSGTRAVIVKRKAPDMDKIGNRVKRLKEEHIATWCYDDMNPYRTWNYHGSYEVKPTGSASSMINHVVKMLSKPWDTLNSVTSISMTDTTPFGQQRVFKEKVDTKAPEPPTGVAEVMDIISDWTWRLLSRQKKPRLCTRDEFKAKVNNHAAMGSIFEEEHQWQTAKEAVEDPGFWALVDREREAHLAGRCETCVYNMMGKREKKLGEFGKAKGSRAIWYMWLGARFLEFEALGFLNEDHWLSRENSYAGVEGLGLQRLGYVLRDISRRPGGKMYADDTAGWDTRITEKDLDNEAKIIDQMEGEHKQLAKAIMELTYRHKVVKVMRPGPGGKTYMDIISREDQRGSGQVVTYALNTFTNMIVQLTRCAEAEGVLIPSMRERKLTPAEHRALLLWLDTEGVKRLKKMAISGDDCVVKGEDERFATALYFLNAMAKVRKDIQEWKPSSGWADWQEVPFCSHHFKELQLKDGRTIVVPCRHQDELVGRARVSPGAAWTVRESAGLAKAYAQMWKLMYFHRRDLRLMANAICSAVPKDWVPTGRTTWSIHGKGEWMTNEDMLEVWNRVWIRENPHVEDKTEVADWKDVPYLGKREDQWCGSLIGSRTRATWAENIWVAVNQVRAKIGKEEYSDHLSSQQRFENWGEVRFSGVL",
    "output": "[Capsid protein C]: Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKTLVSYDIVEDKVRRKVFEACKDYGLTNVQYSLFFGDMTHNRREELFQRLRRIIGRQEGKVLICPVCDKDLRLSKAIEVSAGMPEEAAEAAVSYPGRSRKKARAG",
    "output": "CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "GLFTLIKGAAKLIGKTVAKEAGKTGLELMACKITNQC",
    "output": "Antimicrobial peptide active against the Gram-positive bacterium S.aureus (MIC=50 uM) and against the Gram-negative bacteria E.coli (MIC=12.5 uM). Has no antifungal activity against C.albicans. Shows hemolytic activity against human erythrocytes only at high concentrations (LC(50)=100 uM)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSSQSLYKVSGNIAANALVNNDKYKTMYQESIVNPEGFWREHGKRIDWIKPYTKIKKTSFDDHNLSINWFYDGTLNASANCLDRHLAEHSDRVAIIWEGDNASEQRKITYGELHADVCKFANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHSVVFGGFSPDSIASRVIDGKSKVIITSDEGMRGGRAIPLKRNIDDALKNPDVTTVEKVIVLKRTGGKVDWVEGRDVWWHSLMETASEYCQPEEMDAEAPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFDYKAGEVYWCTADVGWITGHSYMVYGPLANGATVLIHEGVPNHPSPARLGEMIDRHKVSILYTAPTLIRALMAEGKQHFDKFDGSSLRIMGSVGEPINPEAWRWYHEVIGHEHCPIVDTWWQTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGENEGNLVLLDSWPGQMRTVYGDHERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVESALVSHELVAEAAVVGYPHDIKGQGIYAYVTLTRGTEETEELRQELRQWVRKEIGALATPDLIQWATGLPKTRSGKIMRRFLRKIAANEVTNLGDASTLADPAVIETLIESRLNRTE",
    "output": "Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFTSAHANRSAQASASAGHYAHRSGEQTANGLISEIVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQSAGLPLSKVMQISQLSPCHTVDSMIRALRTGNYSVVICWLTEELTAEEHERLVNAAQEGCAMGFIMRPVRNQGTLGRQLSGLKIHSNLYH",
    "output": "Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLTFARQQQRRNVRWLLSLSLLVLLATLLSLCAGEQWIAPGDWLSARGELFVWQIRLPRTLAVLLVGAALALSGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLAGWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSFDLRQLMYWMMGGFGGVDWQQSWLMIALIPVLIWICCQSQPLNMLALGETSARQLGLPLWFWRNLLVVATGWMVGVSVAMAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGAIALLLADVVARLALASAELPIGVVTATLGAPVFIWLLLKSAR",
    "output": "Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTKSPLTLYLAAPRGFCAGVDRAIKIVEMAIEKWGAPVYVRHEIVHNKFVVDGLRAKGAVFVEELDECPDDRPVIFSAHGVPKAIPAEAERRQMVYVDATCPLVSKVHIEAERHAEHGLQIIMIGHRGHPETIGTMGQLPEGEVLLVETVADVARIAVRDPARLAFVTQTTLSVDDTRDIVAALQARFPQIVGPHKEDICYATTNRQEAVKAVAPKSDALLVVGAPNSSNSRRLVEVAAKAGCSYAQLVQRADDIDWRALDGIATIAVSAGASAPELLVNEVIDAFRARFDVTVEVVETAVEHVEFKVPRVLRQPA",
    "output": "Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFAKQIDIHWQKMKGIKFLHWLLGTVLLWVSLSTPALAIPALDYNPWEAIQLPTTATILDMSFIDRHHGWLVGVNATLMETRDGGQTWEPRTLVLDHSDYRFNSVSFQGNEGWIVGEPPIMLHTTDGGQSWSQIPLDPKLPGSPRLIKALGNGSAEMITNVGAIYRTKDSGKNWQALVQEAIGVMRNLNRSPSGEYVAVSSRGSFYSTWEPGQTAWEPHNRTTSRRLHNMGFTPDGRLWMIVNGGKIAFSDPDNSENWGELLSPLRRNSVGFLDLAYRTPNEVWLAGGAGALLCSQDGGQTWQQDVDVKKVPSNFYKILFFSPDQGFILGQKGILLRYVTDLTAAPA",
    "output": "A factor required for optimal assembly of photosystem II (PSII), acting in the early stages of PSII assembly. Also plays a role in replacement of photodamaged D1 (psbA). Assists YidC in synthesis of chlorophyll-binding proteins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVKVYAPASSANMSVGFDVLGAAVTPVDGTLLGDVVSVEAADHFRLHNLGRFADKLPPEPRENIVYQCWERFCQALGKTIPVAMTLEKNMPIGSGLGSSACSVVAALVAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENGIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPQLAAALMKDVIAEPYRARLLPGFSQARQAVSEIGALASGISGSGPTLFALCDKPETAQRVADWLSKHYLQNQEGFVHICRLDTAGARVVG",
    "output": "Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPLFARLCQPQSRRMFSSISSFSALSVLRPQTGMLLNSSPLKTPSFTPLGFGLIGQRRWKSRGNTYQPSTLKRKRTFGFLARAKSKQGSKILKRRKLKGRWFLSH",
    "output": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "KEGYLVNHSTGCKYECFKLGDNDYCLRECKQQYGKGAGGYCYAFGCWCNHLYEQAVVWPLPKKTCN",
    "output": "Beta toxin that binds site-4 of sodium channels (Nav), reduces peak current (observed on Nav1.6/SCN8A (IC(50)=172 nM), Nav1.1/SCN1A, Nav1.4/SCN4A (weak) and Nav1.5/SCN5A (weak)), shifts the voltage of activation toward more negative potentials (observed on Nav1.6 and Nav1.2 (weak)), and induces resurgent currents at negative voltages following brief and strong depolarizations (observed on Nav1.6, Nav1.1 (weak), Nav1.2 (weak), and Nav1.4 (weak)) ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKYINSLEK",
    "output": "Carrier of the growing fatty acid chain in fatty acid biosynthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSGFVLAIDQGTTSTRAILFDGQMKVAGSGQKEFAQHYPASGWVEHDPEEIWASVVTTVKAALKNAGKAASDVAAIGITNQRETVVVWDRATGKPIHNAIVWQDRRTAPLCQKLKKQGLEKKFTRKTGLLLDPYFSGTKIAWILDKVKGGRKRAEKGELLAGTIDSFLIWRLTGGKVHATDATNASRTLVYNIAENAWDDELLAILNIPAKLLPQVKDCADDYGVTERDLFGAEIRILGVAGDQHAATIGQACFEPGMMKSTYGTGCFALLNTGSDLVRSKNRLLTTIAYRLNGKTTYALEGSIFIAGAAVQWLRDGIKVIGKAEQSGKLADEADPTQNVYLVPAFVGLGAPHWDAEARGAIFGLTRNSGPAEFARAALEAVAYQTRDLLDAMRKDWKGTSAKTVLRVDGGMVASDWTMQRLADILDAPVDRPTILETTALGAAWLAGSKAGVWPKAKEFAKSWALERRFKPEMDIATRSAKLAGWRDAVRRTLSA",
    "output": "Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MITGKELRIISLLTLDTVFFLLEITIGYMSHSLALIADSFHMLNDIISLLVALWAVDVAKNRGPDAKYTYGWKRAEILGALINAVFLIALCFSIMIEALQRLIEPQEIQNPRLVLYVGVAGLISNVVGLFLFHDHGSDSLHSHSHGSVESGNNDLDIESNATHSHSHASLPNDNLAIDEDAISSPGPSGQIGEVLPQSVVNRLSNESQPLLNHDDHDHSHESKKPGHRSLNMHGVFLHVLGDALGNIGVIAAALFIWKTEYSWRYYSDPIVSLIITIIIFSSALPLSRRASRILLQATPSTISADQIQREILAVPGVIAVHDFHVWNLTESIYIASIHVQIDCAPDKFMSSAKLIRKIFHQHGIHSATVQPEFVSGDVNEDIRRRFSIIAGGSPSSSQEAFDSHGNTEHGRKKRSPTAYGATTASSNCIVDDAVNCNTSNCL",
    "output": "Vacuolar transporter that regulates zinc homeostasis by mediating zinc transport and storage into the vacuole . ZRC1 senses zinc availability in the cytosol, which might be performed through the histidine repeat motifs, and transports zinc from the cytosol to the vacuole if zinc in cytosol is abundant, confering resistance to zinc toxicity . Plays a role in resistance to zinc shock resulting from sudden influx of zinc into cytoplasm when ZRT1 and ZRT2 are induced in response to zinc depletion ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDYTLTRIDPNGENDRYPLQTQETVSGDPLEQHVHRSVYMGKLENAMHDMVNWGRKNSLWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADFMVVAGTCFTKMAPVIQRLYEQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFLPVDVYIPGCPPRPEAYMQALLLLQESIGKERRPLSWVVGDQGVYRANMQPERERKHAERIAVTNLRTPDEI",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDYLPLFHKLQGGRVLVVGGGEIALRKARLLADAGGVLRVVAPDVDGQLAALAREGGGEVLVRGYQAADLVGCRLVIAATDDPGLNAQVSADAQALSLPVNVVDAPALCTVIFPAIVDRSPLVIAVSSGGDAPVLARLIRAKLEAWIPSAYGELAGLAARFRHKVKSLYPDVNQRRGFWETVFQGPIAERQLAGQGAEAERLLQAMVDGAPVQQGGEVYLVGAGPGDPDLLTFRALRLMQQADVVLYDRLVAPAIIDMCRRDAERIYVGKRRADHSVPQDQINRLLVDLARQGKRVLRLKGGDPFIFGRGGEEIEELAEHGIPFQVVPGITAASGCSAYGGIPLTHRDYAQSVRFVTGHLKDGTSNLPWNDLVAPAQTLVFYMGLVGLPTICAELIRHGRAASTPAALVQQGTTRNQRVFTGTLADLPDLVAQHEVHAPTLVIVGEVVQLRDKLAWFEGSQNS",
    "output": "Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPDATGVIARNPFEEAPSRLNQYTPEEAAALQARLEKKLGPEYISSRPGAAGLKVHYLAADKCINLANEVFGFNGWSSSIQNIQIDFVDESPNTGKVSLGLSVIVRVTLKDGAYHEDLGYGHIENCKGKAAAFEKAKKEATTDALKRALRNFGNVLGNCIYDKDYISKVSKLKTVPSKLDVGDLHRHPDFAPIKKEPMRVKPSLEDDDLPPNPSIAGRNTSTNSAADMDAEFGSDVFDEADFNVGEGEYPDGIVAEDTQKRHQPPTPVGRPNAHLNLPKHALGAQASGNQHVVTPSKPERPMNLAPAGRQIPNQALNNRPFPPPAQNQYTNQRQSVPLPGSNGGLQNGRSIPLGQRASNGMATGSDAGAQVPIKQEHGAKQPNPAPQNTAVPATPGINGQGPPVVGFLSARGADMLRENPHSAATVAPAFNPHAESPSIRKTAGVDHTKSIPISKPMLAGSASPLSNQTRDFINPSAEMHRKIGAPSGSVVGGPMNRGPSVSSYRPLTRPNVDPKAAAQNNTAAANRMAPNMNGKRPPLNDVTNETLPGGNGCTPAPGLNDPKRAKYDESMSAQQHQQQHQH",
    "output": "Involved in DNA double-strand break (DSB) repair and recombination. Promotes the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVIKSNDVREPFNEDKLRSGMLRALEKRPVSADDVEMALNHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKDFGEEIARLQD",
    "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKADLMDRLQAALDNEAGGRPAMEPGNGSLDLGGDAAGRSGAGLEQEAAAGAEDDEEEEGIAALDGDQMELGEENGAAGAADAGAMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQSQPPAAAQQASQQRGPGKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKAGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFETDEVELSYAKNGQDLGVAFKISKEVLADRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEDCTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGSGGIGYPYPRGPVFPGRGGYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY",
    "output": "DNA- and RNA-binding protein involved in several cellular processes such as nuclear chromatin organization, telomere-length regulation, transcription, mRNA alternative splicing and stability, Xist-mediated transcriptional silencing and mitotic cell progression. Plays a role in the regulation of interphase large-scale gene-rich chromatin organization through chromatin-associated RNAs (caRNAs) in a transcription-dependent manner, and thereby maintains genomic stability. Required for the localization of the long non-coding Xist RNA on the inactive chromosome X (Xi) and the subsequent initiation and maintenance of X-linked transcriptional gene silencing during X-inactivation (By similarity). Required for the topoisomerase TOP2A protein stability and activity in a RNA-dependent manner . Plays a role as a RNA polymerase II (Pol II) holoenzyme transcription regulator. Promotes transcription initiation by direct association with the core-TFIIH basal transcription factor complex for the assembly of a functional pre-initiation complex with Pol II in a actin-dependent manner. Blocks Pol II transcription elongation activity by inhibiting the C-terminal domain (CTD) phosphorylation of Pol II and dissociates from Pol II pre-initiation complex prior to productive transcription elongation. Positively regulates CBX5-induced transcriptional gene silencing and retention of CBX5 in the nucleus. Negatively regulates glucocorticoid-mediated transcriptional activation. Key regulator of transcription initiation and elongation in embryonic stem cells upon leukemia inhibitory factor (LIF) signaling. Involved in the long non-coding RNA H19-mediated Pol II transcriptional repression. Participates in the circadian regulation of the core clock component BMAL1 transcription. Plays a role in the regulation of telomere length. Plays a role as a global pre-mRNA alternative splicing modulator by regulating U2 small nuclear ribonucleoprotein (snRNP) biogenesis. Plays a role in mRNA stability. Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Enhances the expression of specific genes, such as tumor necrosis factor TNFA, by regulating mRNA stability, possibly through binding to the 3'-untranslated region (UTR). Plays a role in mitotic cell cycle regulation. Involved in the formation of stable mitotic spindle microtubules (MTs) attachment to kinetochore, spindle organization and chromosome congression. Phosphorylation at Ser-58 by PLK1 is required for chromosome alignement and segregation and progression through mitosis. Contributes also to the targeting of AURKA to mitotic spindle MTs (By similarity). Binds to double- and single-stranded DNA and RNA, poly(A), poly(C) and poly(G) oligoribonucleotides . Binds to chromatin-associated RNAs (caRNAs) (By similarity). Associates with chromatin to scaffold/matrix attachment region (S/MAR) elements in DNA . Associates with chromatin in a chromatin-associated RNAs (caRNAs)-dependent manner. Binds to the Xist RNA. Binds the long non-coding H19 RNA. Binds to SMN1/2 pre-mRNAs at G/U-rich regions. Binds to small nuclear RNAs (snRNAs). Binds to the 3'-UTR of TNFA mRNA. Binds (via RNA-binding RGG-box region) to the long non-coding Xist RNA; this binding is direct and bridges the Xist RNA and the inactive chromosome X (Xi). Also negatively regulates embryonic stem cell differentiation upon LIF signaling. Required for embryonic development (By similarity). Binds to brown fat long non-coding RNA 1 (Blnc1); facilitates the recruitment of Blnc1 by ZBTB7B required to drive brown and beige fat development and thermogenesis (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MHRYRSHTCAALRKTDVGSNVRLSGWVHRVRDHGGILFIDLRDHYGITQIVADPDSPAFKVAETVRGEWVIRVDGEVKARADDAVNTNLPTGEVEIFATEIEVLSPAKELPLPVFGEPDYPEDIRLKYRFLDLRRETLHKNIMSRTKIIAAMRRRMTEIGFNEFSTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMVAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLEMSFVTQEEVWETMEPVMRGIFEEFAEGKPVTKVFRRIAYDDAIRTYGSDKPDLRNPIEMQAVTDHFAGSGFKVFANMIANDAKVEVWAIPAKTGGSRAFCDRMNSWAQSEGQPGLGYIFWRKEGDKLEGAGPIAKNIGEERTEAIRKQMGLEDGDACFFVAGLPSKFYKFAGDARTRAGEELNLVDRDRFELAWIIDFPFYEWDEDNKKIDFAHNPFSLPQGGMDALENMDPLEIKAYQYDLVCNGFEIASGSIRNQLPEVMVKAFEKVGLSQQDVEERFGGLYRAFQYGAPPHGGMAAGIDRVIMLLVGAKNLREISLFPMNQQALDLLMGAPSEVSPAQLRDLHVRLAPVQKS",
    "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLLFQKTLSRVAAPISVAANLILILLIIFKSPAQMGNYKYLLIGLSIFEMSYAVLDVVSETTVLSIKKSFVVVVPYKDRSFGQETAMDINLIYCGFFGFSMGMFVVIFAYRSFLTTGNTILRKFEGFKIISWFAYPLFYAIVWILVAWGPLASFPEMDIVVRPFLLDELNMTVDEVAYTGRLFYSTIDNSLRYSAILTGVLQWVLTASSLFLVIFFGLRCYFHYGKLVQLTDVQSIRLRQLQNQLFLALVCQATVPLILMHIPVTILYTCCVLNIVFNPFSVATTIALFPAIDPLPTIFIVKNYRVALFEFVCPSCLCWSETLKHMGSNRITSYRSNTVNALSM",
    "output": "Probable G-protein coupled receptor."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSFLTVPYKLPVSLSVGSCVIIKGTLIDSSINEPQLQVDFYTEMNEDSEIAFHLRVHLGRRVVMNSREFGIWMLEENLHYVPFEDGKPFDLRIYVCHNEYEVKVNGEYIYAFVHRIPPSYVKMIQVWRDVSLDSVLVNNGRR",
    "output": "Binds lactose with high affinity. Strong inducer of T-cell apoptosis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGIFTLCSCGVPCPTRSFYRRHMASGCDLLPTRQQLADVGYTEPTVIAEVVTPPTQAPLELFVEISPPVLAPFEPSVEISLPIQAPAEPIVEASPPAATQFVGIEALIASGPCFFGSFGPFEEYYSSPVGPLTRFDTLRREGHCAARARVAAVAAKAVIVQQTLSETAAAMRATLPLWMKGQVAPPVKSKRALKREAKAKAKADYLASDEAYYKATDGLTALPPGVSRDVHMRQLDAMEVAYLAHVGDVAARGFQRRQVLRAAYKARCEKRAFKRFLEEVDFLCLPVHIVDKIQTPFDGEQAAAPEMQKGMVYATSRRQVKTRRSFSSFLPKEDFSFTLGVCPARSPTVTPSSTPSTSRSSSPEPRVSSPSGVLPEKAACIGFCSHGSECTEHFCFGYLNLKSEALASQYLAWLLQTKLPGGISCFELEVSSYLEQCQDTMEAIDLWWHAMDRYCFNFKSSKYVILDNFLCKHSIAKDQTPREFLAKHRIAKAKALHRVPSRKEKMQALCEQRADKAWDAYIELNKNCKVGEGPLEYLKAAKDRCVEFFSPFTKYCNEAIRSLNPLVAILGPFKDGFWTCFNNLREKCLKMVNDHWLAFAAGTTLVLSLIFLLCIICLVKIFSILIANLGLGVVAITTLVTALVVGFFLFNGMLEQAADLQLCSLVASDFLNFLAQNQGSALVAGTMASVQDDLRGQGVSWCFSALYKLISRVVPVGIKETSILFNSIGNVSRSANHSKDFFLNMKEMACSWMDALSDAMALISDDSVSAMQVLKHLCEHDFLDWAKKVERYAGETYDSLIISPAERLKILRILADQQESFQKAFYNPRIASKAPRLMLTEFNRLSTLLRDAHNALSRASLFDRQRTPPFWVHLYSENGGTGKSMAMMPLGNHMLDAIGEPKTCRFVTRNVASKFLNGYQHQPCFLMDEFGAAPKQDYSDEVTMLDLVSPNALTLNMAAIGEKNTMFTSKLIISTANRRLAHPDVKLGANLDGFLRRRNILAEVVLVSGKPHFHEFNLLAPRTEQKVYLNRAMQESQVPDPLTPQEFYSLCTENFVNFLNQQSSTVAMSAGLNYVRSSDFSHLKDFLLFKIGLDFEENEVERIVTDYGNSLKNETIFPPEHEQIFQKWKDALDSLTLPELVSLLDKSVSETFVYTLISENHPNVVMSSLTPYECMIYAICKKKYREGTEAKLPFPEGETTSYGASFLSFVAQVALCIPKWALFCVALCAVLLVGYLIIKFAIFLFSGVVTLLGALAFSNLSGDGAEDSPSFDTNRKRGGVKFEYSTKWDASSTNRFAESYSENGTIPAGTSWADFFGEGPEEEPSQSLLNLLKHQVVLIAEPTKVVYNCIALGGRNFLITKHVWDLMPACNYGLYGYAVAKDRIFISPRIRPCAQLKGRDLVIVQLPDSVPPFTSLPRDIFLENMAKAPKTANACLVVAKPLFERRSVAKLEQTIYPFKQLPQVHSKDTYSCGSLGSKQMPACYSYVFETYAGLCTSPLIAQEGGRCIILGLHVVGDRSKMGYAQIVTLDDFSDVALSDKVGQGPEEMYIPTKNSECFGSVTKLGAWTGPKPYFLEKTSLIPSLISTSIDVERTTEPAILSQRDKRLKDSINPEFDVFLEGMKKYAVEAHSLDEDLEVFEDALDRVFLEIPEHACEDLTNDQVCNGIEDDPYAEGIVMQTAEGFPFCTQRPAGASGKSWLFAGAPGDWHIVPGSLLANEMHKKEVAPSRGLFEPLIGIDFPKDEKVDSSKVYIKPKTRLFTILPVDYNILVRKYFLSSVSHIMTQHNTIPVKVGIDCLSNEWSILYHQLRSKGTNWFNGDYSRFDGITPRNVLQGIVKRINKFYNNKNSLAITDSNLSINSDLARSLLTDMASTRYGLTNGDLWYVTSGIPSGFPLTVIVNSLVNNFFIHFSYIKLMKREELNSLYPLHSFRQMVAYATYGDDNLVSVNDVITEKFNLVKIADLLAEHGVTLKNGADKNEEILSPFYPLEKVDFLKRKFVHYQGHVVAPLNPVNITERLHWIRKGLGEADATLENCSSAAFEALFHGRCYYDTLVAKIYKACAASKLSIQLPTYNDALAIFLSNDSFAKAIQTISLDLPKAIFVNKSNYFVSEIFPDVFFCSNERNVTLHKLLEITTTRNICYISRNYESRNSSRGLFSLKGEGWALAPVSARLVVYKNMQKPVYFVDEANDGLALAYCLDYMLRIKGVSRSRLAQVLYNIFGHDETLCSRIASNFSLLDSNKYMPPHKK",
    "output": "Picornain 3C-like protease is a thiol protease that probably cleaves the B and M polyproteins.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNIQNDKERLLNGSIDEIEIITTDNNENDTIRNDDILKNSQLREQQQHQQIQQQIQQQKKESSLSTIASVIAFYFFISISLVFLNKILLSDFKFEYPLFITWYQQIISFVSIYIMTSISKSVPALSFLPEFEFKSATASKVLPVTAVLTGMVIFNNLCLEYVEVSFYQVARSLTICFSLILTYIVLKSKTSYRATMACLVVFLGFVLGSAGEVNFSWLGIIFGLLSSFFVALYSIAVKRVLPAVDGNEWRLSIYNTAISIGLIFPLILVSGEANTILDEPLLYSGTFWFYMTVAGLMGYLISISVFMQIKHTSPLTNTISGTVKACVQTILAVVFWGNPISTQNAVGILLVIGGSFWYSMQRFFEMKK",
    "output": "Antiporter specific for GDP-l-fucose and depending on the concomitant reverse transport of GMP. Involved in GDP-fucose import from the cytoplasm into the Golgi lumen."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNQNIIYTVYGDLKLTLKNMRPDVLLHNPVMFLTEVSLFVSIFIYIFPSFFGVPYTGTYRSFYVAVVVLLFLTVFFSSISTALSEGKSKAITDSLKKFKTDVIAHVQKDGNIVDVRSNELKKNDIIIIYKDEIVPIDGEVIEGSGYVDESNVTGESRAVMKVIGDTVTGSTRLVTDKLKIRATADPGSTFIDKMIELVEKSTREKTPNEISLTVFLSGLTLIFLVITASIFAISHYFGRTANIVMLIVLLIALIPTTIGALLPAIGIAAINKVSEYNIIAKSGRAIENAGDIDTIILDKTGTITIGERKAVKFYPNKGISDVEFAKLAAMSSYYDQTKEGLSIFELAKKQGAEISKDDLKGYEFIPFSSETKFSGIQSPSDTVIKGSLKALKEKFQVADEFIEALCKEISMRGGTAIPVVHNGKFAGVIELQDLIKPGIKERISEIKNMDIKTVMCTGDDEVTAQYISAQAGIDEYIANSKPVDKYNVVIREKEGQRMVAMVGDGTNDAPALAKADVGLAMNNGTQAAKEAANMIDLDSNPTKLMDVIFLGKQILITRGSLTTFSIANDISKYFVIIPAIFYMFPSLSLVNILDLTDPIVAVTSALIFNTIIIVFLIPLALGGVHYKPTSISEMLKRNLMIYGIGGVITPFIAIKLIYMLLIAWGVTW",
    "output": "Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI",
    "output": "Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAWVSFYLLPFIFSTGLCALPVLTQPPSASALLGASIKLTCTLSSEHSTYTIEWYQQRPGRSPQYIMKVKSDGSHSKGDGIPDRFMGSSSGADRYLTFSNLQSDDEAEYHCGESHTIDGQVG",
    "output": "V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSY",
    "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATISPGGAYIGTPSPFLGKKLKPFSLTSPILSFKPTVKLNSSCRAQLIDTVHNLFIGVGVGLPCTVMECGDMIYRSTLPKSNGLTITAPGVALALTALSYLWATPGVAPGFFDMFVLAFVERLFRPTFRKDDFVVGKKLGEGSFGVVYKVSLSKKRSNEEGEYVLKKATEYGAVEIWMNERVRRACGNSCADFVYGFLDKSSKKGPEYWLLWKYEGESTLAGLMQSKEFPYNVETIILGKVQDLPKGLERENKIIQTIMRQLLFALDGLHSTGIIHRDVKPQNIIFSEGSRSFKIIDLGAAADLRVGINYIPKEFLLDPRYAAPEQYIMSTQTPSAPSAPVAAALSPVLWQMNLPDRFDIYSIGLIFLQMAFPSLRSDSNLIQFNRQLKRCDYDLTAWRKLVEPRASADLRRGFELVDLDGGIGWELLTSMVRYKARQRISAKAALAHPYFDRQGLLALSVMQNLRMQYFRATQQDYSEAANWVIQLMAKNGTEKDGGFTETQLQELREKEPRKKANAQRNALASALRLQRKLVKTVTETIDEISDGRKTVWWNRWIPREE",
    "output": "Serine/threonine protein kinase required for state transition by phosphorylating light-harvesting complex II outer antennae (LCHII). State transition plays a central role in response to environmental changes and allows to adjust to changing light conditions via the redistribution of light excitation energy between photosystem II (PSII) and photosystem I (PSI). Phosphorylates the minor light harvesting protein LHCB4.2/CP29 and is involved in the light-dependent phosphorylation of TSP9. Acts as a key component of the long-term response (LTR) signaling pathway. Mediates phosphorylation-dependent PTAC16 subcellular localization to regulate plastid gene expression ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MYFIDEAINEIKAGNGGNGVVSFRKEKYVPLGGPDGGNGGKGGSIFFIGEQSENNLLKLKYQKHLKAKNGENGKNKNKHGANAENIYIKVPLGTIIYNLQNEITGEILKHGEILTIAKGGRGGKGNKSLATFKNPVPKYAEKGGIGESFKIKTELKILADVGLIGYPSVGKSTLISIISDAKPKIADYPFTTLKPYLGMVYVDNESFIVADLPGLIPNAHLGKGMGIKFLKHIERCRILIHMCDMSKSNPLQDIENLNQELKIYNKNLLKKPQIIIANKMDIIGAKTKLIELQKKILNKNIIPTSLLKNQNLKILKYKMLEMIKKNVVNLPLCENSSFKTYTLEEEKPDFVIKKDNQGFFVVKGEKIEKFFYKTDFNNEEATKKFAIFLKKIGVEEELIKKGVYFSKNKIKICDRVFEFIT",
    "output": "An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPRYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLQHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGDVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTSMVSLCEQLSKLGVWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGAGANELPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIVDEVDEEGAIGRSMADAPEIDGAVYLNGETNVKPGDIVRVKVENADEYDLWGSRV",
    "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVQVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR",
    "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMCISKLPAVLLILSVALNHLRATPVRSGSNPQMDKRKCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTYGKRNAAGDPNRESLDFLLV",
    "output": "Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAEGRVQRVASEFQKVISLLLRTRIKDAKLASATITEVDLSKDLSYAKIYYTCLAIEDAEYIDKAFEKSKGFFRSSIAKSLSLRIVPNLKFIYDTSLDYGMQMEEKIQQALEADSKIIKQDDKSLQENYKQNDKETKAEKLR",
    "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDLLNTTFLSIGLAIDAFAVSLSSGFIIKHIKFNKALKIALFFGIFQGVMPLIGWLTGLTFRDALANFDHWIAFILLAAIGGKMIYEACQDEEENKKFNPLDNYTLFALAIATSIDALAAGLGLSVLRVSILLACTLIASITFSLSFIGVFIGHKFGSIFNQKLEILGGITLIGIGTKILVEGLIIH",
    "output": "Probably functions as a manganese efflux pump."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MENLPNHEENDDVGYHQSPGPIDPNDHSASETPVYSTMSTDSFAYHRTCSETSGGGFSDQIDETSSFCTEASPSDWPVLTESNNSASSNFPTVFDLKHNQIETDEHLAVQEISEPELETMKERFSKLLLGEDMSGSGKGVCTAVTISNAITNLYATVFGQNLRLEPLEIEQKTTWKREMNCLLSVCDYIFEFIPKSQNLSNGATVEVMESRPRADIYINLPALRKLDSMLMEALDSFQKTEFWYAEEGSLSMKSTRSATGSFRKVIVQRKEEKWWLPIPLVPLQGLSEKARKQLKSKRESTNQIHKAAMAINSSILGEMDIPDSYMATLPKSGKASTGDAIYRHMTSSGRFSPEKLLDRLKIVSEHEALQLADRVEASMYTWRRKACLNNSKSSWNMVKDLMSITERSDKNYVLAERAESLLFCLKQRYPELSQTSLDICKIHCNKDVGKAVLESYSRVLEGLAFNIVAWIDDVLYVDKTMRGEE",
    "output": "Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSQNSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFKFEDAAKAYDYNIAHGGEVVKTIIFGPE",
    "output": "Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) and xylitol as substrates, leading to the C2-oxidized product D-fructose and D-xylulose, respectively."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDDAVELAPGATTLVPTGLAIHIADPSLAAVMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSIWNRGQDSFTIEPGERIAQMVFVPVVQAEFNLVEAFDATERGEGGFGHSGRK",
    "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKSLLDLFKQFTPDEHFDAIKIGMASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIDLAAPCAHIWFLKSLPSRLGLVLDMTLRDIERVLYFEAYVVTDPGMTPLKKFGIMSEDDYDAKRKEYGDEFVAKMGAEGIKELLEGIDIEIEIEKLRGDLTGSEVKVKKNAKRLKVLEAFKKSGIKPEWMILEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNSRLRRLLELKAPEIIARNEKRMLQEAVDSLLDNGRRGKAMTGANKRALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVITVGPTLKLHQCGLPKLMALELFKPFIFSRLEAMGIATTIKAAKKEVEAGTPVVWDILEEVIKEHPVMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSVEAQLEARTLMLASNNVLFPASGEPSIVPSQDVVLGLYHATREKINGKGEGLVFADTGEVQRALDAGEAELHAKISVRLTEWTKDKATGEFVPETKLVDTTVGRALLSEILPKGLPFSNLNKALKKKEISKLINASFRKCGLKDTVVFADKLLQNGFRLATHAGFSVAIDDMLVPPQKAEILARAEAEVKEIEQQYVSGLVTAGERYNKVVDIWGKAGDDVSKVMMDQLKVQKTIDRNGKEVNEESFNAIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVTEDDCGTSNGSLMRAIVEGGEVIESLRDRILGRTAAEEVLHPETRAVLAQPGRMLDEDLIEELEAAGVDEVKVRTALTCETRYGLCAKCYGRDLGRGGLINLGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSNGIIGFNATMRYVTNTKGELVVIARSGEIIIQDEHGRERERHKVPYGATLTVKADQNIKAGTILANWDPLTRPIITEYAGTVKFENVEEGLTVAKQVDEVTGLSTLVVIDPKRRGSAKVVRPQVKLVDADGKEVKIPGTDHSVTIGFQVGALIQVRDGQEVGPGEVLARIPMEGQKTRDITGGLPRVAELFEARSPKDKGMLAEMTGTISFGKETKGKVRLQITDPDGKVWDELVPKEKNVLVHEGQVVNKGELIVDGPADPQDILRLLGIEELSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVENPGESTYIAGEQVERSEILNTNEALQAEGKLPATYSNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGLAYHQARKAKDAMDEAERRAIADAEAAELASAGTHDAAAEIDGSADTAD",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIRLEQVIEILKKDNNFREISSAGEYYFNWPKEVNFDQLSYDSRKSTENTLFFAKGLNFKKEYLTDLEAAFYVSEFDYEVALPAIIVTDVKRAMALIAASFYDFPQNKLKTLALTGTKGKTTSAYFAKAILDKMNGGKTALLSTAQTTLDGKNYFKSELTTPESLDLLEMMAKALTNGMTHLVMEVSSQAYKTERVYGLTFDVGVFLNISPDHIGPVEHPTLEDYFYCKRQLLKNSRYFVANSEMNHFAIIKEELKERKIPHAFYGADSENKIIESKGLHFVTDGSVSGAFDIRLLGRFNQENALATALATKALGASLENIHDGLALAVVPGRMELLTAKNGAHIYIDYAHNGLSLENLVEVVEEHHAGQLVLVLGSTGNKGESRRKDFGQVIEKHPRLDVILTTDDSNREDPKIIADEIASFVSRTLDFELDRELAIKKAVSKTKSTDDAVIIAGKGTDMFQLKDGKRQPYIGDTAAAQKYL",
    "output": "Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "LGKEAAVKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPSDTHLDSLVGQALFGDGAAALIVGSDPIPEIEKPIFEMVWTAQTIAPDSEGAIDGHLREAGLTFHLLKDVPGIVSKNIDKALVEAFQPLNISDYNSIFWIAHPGGPAILDQVEQKLGLKPEKMKATREVLSEYGNMSSACVLFILDEMRKKSAQQGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAL",
    "output": "The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKMSEEEEFLLFKNISLVGPWDGPQYHLAPVWAFHLQAVFMGFVFFVGTPLNATVLVATLRYRKLRQPLNYILVNVSLGGFIYCIFSVFIVFITSCYGYFVFGRHVCALEAFLGCTAGLVTGWSLAFLAFERYIIICKPFGNFRFSSKHALMVVVATWTIGIGVSIPPFFGWSRFVPEGLQCSCGPDWYTVGTKYYSEYYTWFLFIFCYIVPLSLICFSYSQLLGALRAVAAQQQESASTQKAEREVSHMVVVMVGSFCLCYTPYAALAMYIVNNRNHGVDLRLVTIPAFFSKSACVYNPIIYCFMNKQFRACIMEMVCGKPMTDESELSSSQKTEVSTVSSSQVGPN",
    "output": "Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal (By similarity). Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors (By similarity). Involved in ensuring correct abundance and localization of retinal membrane proteins (By similarity). May increase spectral sensitivity in dim light (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLPRIANQRAIVDRRALADAVSAAFAEQGDRSRPAVVELLRGALDSGRAELARRLEARPSAGTECAHGQAFLVDQLVRVIHDHVVGKVYRASNRSTGERIAIIAVGGYGRGEMAPHSDVDIAFVTPIKPTSWCEQVIEAILYFLWDLGLKVGHSSRSLDEVVRMAKSDLTIRTALLEGRYVWGDRDLFDAASARFWNEVVNGTEKQFVAEKLQERNERHKRLGDSRYVVEPNVKEGKGGLRDLHTLYWIGKYIHKVRDASELVDVGLLTAEEYRAFRRAENFFWAVRCHLHAITRRAEDRLTFDLQREVAMRMNFADRPGKSAVERFMQYFFLQAKQVGSLTGVFLAQLDGQFARQKRSFFASLRSRRKKVGPFFIEGGKLGVPAEDTFQQDPVRLVELFAVAASEKVEIHPEAMRLARRDAGLIDAAVRKDQRANALFLDVLTSRNDPETVLRWMNEAGVFGRFVPDFGRVVAQMQFDMYHHYTVDEHTIRAIGLLASIEKGEAKADHPLASEVVGKVASRRVLYVATLLHDIAKGRRGDHSVLGAEVAMKLCPRLGLSAAETELVAWLVRWHLLMSATAFKRDLADYKTIADFVNTVQSQERLRLLLLLTIVDIRAVGPGVWNSWKRQLLGDLFVSAEEVLRLGHKQHGRAERIIAKKKAVGAILKERDNLIGTVGRQLGDAYWIAEPEDIIALNLQQMDQALGELLSVEAHWYPARGATLVTVLAADHPGLFYRIAGGIHLAGGNIIDARIHTARNGTAVDNFLVQDPLGRPLNEASQIERLKNAIADALANRVKLVPQLAARPLARPRADAFDVRPIVIFDNKASNRFTVIEVGARDRPALLNRLARALFEARLIVHSAHIATYGERAVDTFYVTDVLGEKVDSEARMKAVEKRLLEAAEDRKVKDAA",
    "output": "Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSTTAYPDTILIIDFGSQVTQLIARRVREANVYCEIVPFQSADEAFKRLQPKGVILSGSPHSTTDIGSPRAPQAIFDAGIPVLGICYGEQTMCAQLGGNVESGHDREFGRAFLDVQEDSPLFAGIWAKGTRHQVWMSHGDRVTSLPDGFTIIGTSPNAPYAVIADEKRKYYGVQFHPEVVHTPDGAKLLQNFVHRIVGVKPGWTMGAYREQAVEAIRKQVGSGKVICALSGGVDSSVAALLAHEAVGDQLTCILVDHGLMRKDEAQQVVEMFREHYNLPLILVDASDRFIGALEGESDPEKKRKTIGRLFIEVFEEEARKLGGADFLVQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRLLGKELGLPDSFIGRHPFPGPGLAIRCPGGVTRGKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYHYDMNFLGNAATRIINEVRGINRVVYDVTSKPPGTIEWE",
    "output": "Catalyzes the synthesis of GMP from XMP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLTRKQHELLMFIHERIKETGVSPSFDEMKEALDLASKSGIHRLITALEERGFLRRLPHRARALEVVRLPQQATAAAPPKGRAPFKPQLVEAGQAMPVAANDTRELPILGKIAAGTPIEAIQQERDRLPVPEAMLGAGEHFVLEIQGDSMINAGILDGDFVVIRRTDSANSGDIVVALVDGEEATLKRLRKKGASIALEAANPAYETRIFGPDRVAVQGRLVGLIRRYH",
    "output": "Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEELSKKHTTRLNKLQKRLRREVGSAIADYNMIEDGDRVMCCLSGGKDSYAMLDILMNLQQRAPIQFEIIAVNLDQKQPGFPEDILPAYLDKLKVPYHILEKDTYSIVKDKIPEGKTTCSLCSRLRRGTLYGFAQRIGATKIALGHHRDDIIETLFLNMFFGGKMKAMPPKLLSDDGANIVIRPLAYCREKDLEEYAQLKQFPIIPCNLCGSQENLKRAAVKDMLNQWDRQYPGRIETIFTAMQNTAPSQGVDREQFDFISLKRDPDVPMTGDVAEADLPAFDFLDIANSGHIDLDAAQRIDVVSFYEA",
    "output": "Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPVIYINLIAAFFMAFMGLLIYRSHLMSSLLCLEGMMLSLFILNSTLALSMHFTLYSMMPIILLVFAACEAALGLSLLVMVSNTYGLDYVQNLNLLQC",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTTSLALYLALGCGLAAVLYGFIQRGWILAQDAGNARMQEIAGAIQQGAAAYLARQYKTIAIVGAVLAILIFFFLGGLTAAGFVLGAVLSGACGFIGMNVSVRANVRTAQAATKGIGPALDVAFKGGAITGMLVVGLGLLGVSLFFWFLSGGIHADPATLKPLLGLAFGSSLISIFARLGGGIFTKGADVGADLVGKVEASIPEDDPRNPAVIADNVGDNVGDCAGMAADLFETYAVTLIAAMALGALLLPNAALAAAVYPLVLGGVSIIASIIGCAFVKASPGMKNVMPALYKGLIVAGAISLVFFFFVTRMVMPDDALGAGTQMRLFGACVVGLVLTAAMVWVTEYYTGTQFKPVQHVAQASTTGHGTNIIAGLGVSMKSTAWPVIFVCLAIYGAYALAGLYGIAIAATSMLSMAGIVVARDAYGPITDNAGGIAEMSGLPDSVRDITDPLDAVGNTTKAVTKGYAIGSAGLAALVLFADYTHALEARGMSLSFDLSDHRVIVGLFIGGLIPYLFASMAMEAVGRAAGSVVVEVRRQFRDIKGIMEGTAKPEYGTAVDMLTTAAIKEMIVPSLLPVVAPILVGMLLGPAALGGLLMGTIVTGIFVGISMCTGGGAWDNAKKLIEEGFTDANGVLHKKGSEAHKAAVTGDTVGDPYKDTAGPAVNPLIKIINIVALLIVPLLPLASNPVKASHAEPAPMVQPAETAPAMPAAPMAEPSAPAASQ",
    "output": "Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSYPQAPSKFVNPDEIIPLSPPTKPPFAQYAASPLPATPHTPYSPPSPSRLSETIPLRPYLSLLPRILLTFFSPCLLPMILTIAHLIQNRSSTASLATSLKSSVLSACSGLAKAAASIKTLPRYLAMQTNQEAIRATQASILAIGTMLMDAITIIEAVVNFIVDTYRSLLLCTIELAVRGTLEILISAVQTISDAVTDTLNSVRSNIQDDIGDANDIIQTAVSAINRVTTLVNLNISVPEFSIPALSFLQNVTIPTTFEDGLITLNSSLPTLTDLKKKMDEIIDTPFEALISEINSTRLEMAASFNSSILSVPSLSSLSANSANDLSNDLCSDLDTSLIDDTAKALHKLSSIAIGLMFLLLFLIWAALAVWEWRKWKLMKDTVDAVNEEWDRDGKSDAWRMVAIVEHPVLERYSGTFLGKIAKMPRTRTNLRWFLSYLAHPTCLALLFISLFGFLSIQFQLVALNALKAHAQSSANSTVTASTNSLVTKLNAAALNSSQEYADSYNEAIAGYQDRINNELFGSWVNTTAVTLNSTLVEFYDEVEKALNASFGGTILYNPINTFMYCILGSKITNLEKGLTWISEHAFVDLPTFPSDILLLSNDSMNEIATPIAAAAVGSGDGGDDDDGVVGTLISHFESALKVERTFYGIMLGVWLALFLIGLAVVIWNSGGREKFMALRGVPSSSSPPGYGPPESKHPRWKAWLTNNHPIYDSYAEKQFRGTTPTNCLESYTHADVPNVNNGNDDHEKSFFKMRDSHAAGPFGSHATSAVRSTIASLAAPGQSFLKLSGRKLTDTTTPYDDKVPLAPVQTSEKYSRDHANSPFPRPSSESSESSAAQPFWVDKFYGAFEGVKSFFPTRSQRLGAALARKASQRTEGSFGASQVPTARTPGHDWIGGHQCLPEKKAEPEWSMVDPRMLGRALEDDKGRYPRVLPPSEMAAANYNPHPVYPRPMSRASTLGEGMVIPSTTSHPDPFQDMPPLPPKHKRASMDYVEEYESSHSRSSREDSRHGGVTSPASSSVSYFAAEPQLVSASKVQVGVAQKGGQATRALAEIVKELQEKRERKDPFGDDYERGL",
    "output": "Involved in cell fusion during mating by stabilizing the plasma membrane fusion event."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEPFRIHKGTAAVLMNDNIDTDQIIPKQYLKRIERTGFGKYLFDEWRYDNERHENPNFPLNAPDRKGASILITGDNFGCGSSREHAPWALADYGFRVIIAGGFADIFYMNCMKNGMLPIVMDKEMREKLAKTDAREQIEVNLENEVITTSTHRFHFTIEKMWKEKLLNGLDEISITMQYEQEIKEYERMVAVY",
    "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLYLTKIRNAESEFTENEQKIADFLRANVSELKSVSSRKMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATAQHLHSSITSDDSLEVIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGCDLSFKLMKIGYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLAHFTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIQRSSELTQRLK",
    "output": "Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARDKFERSKPHVNIGTIGHVDHGKTTLTAAISATLSQYTGKSKKFDEIDSAPEERARGITINTAHVEYETDKWYYAHVDCPGHADYVKNMITGAAQMDGAILVCSAANGPMPQTREHILLAKQVGVPYIVVFLNKADMVDDEELLELVQLEVQELLEKYDFPGSEIPFVAGSALLALEAVANNPTIKRGEDKWVDTIYQLMDKVDEYIPTPERETDKAFLMAVEDVFSITGRGTVATGRIERGKVKVGDTIEIVGLRETRNTTITGLEMFQKSLDEALAGDNVGILVRGIQKTDIERGMVLAAPGSITPHTKFEGEVYVLTKEEGGRHTPFFSGYRPQFYVRTTDVTGTIAQFTSDDGSTAEMVMPGDRIKMTAQLIHPIAIEKGMRFAIREGGRTVGAGVVSKIIE",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEAQNIFLYLLIVFLSLHFVFTTLKGRLSPANTRRLIRLLHIPIKSPVAAAIFARKDTREFLDSSIKLVNEEDDFGFSFDFKPYMISKAETINRALDEAIPLIEPLNIHKAMRYAILAGGKRVRPILCLAACELVGGEERLAIQAACAVEMIHTMSLIKDDLPCMDNDDLRRGKPTTHKVFGESVAILSGGALLALAFEHLTEADVSSKKMVRAVKELAKSIGTKGLVAGQAKDLSSEGLEQNDVGLEDLEYIHVHKTGSLLEASAVIGAVIGGGTEKEIEKVRNFARCIGLLFQVVDDILDETKSSEELGKTAGKDKVAGKLTYPKVIGVEKSKEFVEKLKRDAREHLQGFDSDKVKPLIALTNFIANRNH",
    "output": "Catalyzes the trans-addition of the three molecules of isopentenyl diphosphate (IPP) onto dimethylallyl diphosphate (DMAPP) to form geranylgeranyl diphosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAAPSPSGGGGSGGGGGTPGPIGPPASGHPAVSSMQGKRKALKLNFANPPVKSTARFTLNPNTTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERTVEVACYVCKILDQMPATPSSPMYVD",
    "output": "Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The phosphorylation of the Thr residue by MAP2K7/MKK7 seems to be the prerequisite for JNK activation at least in response to pro-inflammatory cytokines, while other stimuli activate both MAP2K4/MKK4 and MAP2K7/MKK7 which synergistically phosphorylate JNKs. MAP2K4 is required for maintaining peripheral lymphoid homeostasis. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. Whereas MAP2K7/MKK7 exclusively activates JNKs, MAP2K4/MKK4 additionally activates the p38 MAPKs MAPK11, MAPK12, MAPK13 and MAPK14."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNKRFNSEDKIILAIDGLDLSQAKLLLEKCPHVKWVKVGLELFVREGPRVIEILKGLNKKIFLDLKFHDIPNTMSAACFQVSKLGVDIISIHASAGLKALKDSKKASLEGATSVSVKPPFVVGITVLTSFSLKDFQTDLDRNNSIEENVLRLAKLSFDAGLDGCVCSPWEVKMLRSNYKNNFELITPGIRLNIDSKDDQNRIMTPHEAIDNGASKLVIGRSISKAIDPNMALIEIFKSIDSD",
    "output": "Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKSSVEQLNPTRVRINVEVPFTELEPDFQRAYKELARHVQLPGFRPGKVPARLLEARFGRETLLDQVVNEAMPSRYGQALAESEVQPIGQPEIEVIRKEYGQDLAFTVEVEVRPKIALPDFSTLKVVVDPVEVSTDDVEAELRSLRARFGTLIGVDRPVALGDFVSIDLSATINGEKVPNADAEGLSHEVGYGRLIAGLDDALVGLSAGESRVFTTQLATSKHAGQDAEVIVTVKSVKERELPEPDDEFAQLVSEFDTMAELRANLGDQVRKAKYAQQAEKIRDAAVDALLERVDVPLPEGIVQAQFNNALHDALSGLGHDEAKFAEVLAERGSSREEFEAEARSAAERDVTRQLLLDVVADDQKIQVGQDDLNERLLATSQQYGVDAQQLFGFLRENNRLSSLVTDARRRLAVAAVVEAATFTDSDGNTIDTSEFFGKHAQSDKADQKTEEADPNSDAIDEEVDEAAE",
    "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFNTYTNSLQWPIRSRNQQDYCSLLPERSESYKLSKAYTSSRCYCVSSRSSCCCCCSTPSSSSFVKPKVLINPGFVLYGVRQSTLIQWPSFQRRLLVGGGRLMGCEVYSSCDGIRRKNRSFKLRCLEESDECCGGRSCSDDVEAMISFLSEELIDEERKWNLVSRVKEKKKVGNVRKVSVEGSNSYGNGRVSQRVKKPEGFGRRKEIKEDVKLNERYDCEHCGRRKKSSELESESRRGSKLVTGEYIGKSYRGDEEREVRPRRRKSSSCSSYYSLASSGEFESDTEDQEEDVEIYRENVRSSEKKVVDQSAKRLKSRKEASQMHSRKKRDESSTGVDSRYQKQIFEEGENSNQAVTLNQRRRKKFSQTENRVSESTGNYEEDMEIHEVHVNDAETSSQNQKLFNEREDYRVHSIRNDSGNENIESSQHQLKERLETRYSSEDRVSEMRRRTKYSSSQEEGINVLQNFPEVTNNQQPLVEERISKQAGTRRTTEHISESSEIHDIDIRNTYVSQREDQIRNQEVHAGLVSGLQSERKQQDYHIEHNPLQTTQSDRTSVSVSHTSDAVRYTEIQRKSEKRLIGQGSTTAVQSDSKVEKNGAQKEDSRLDHANSKKDGQTTLGLQSYQSKLSEEASSSQSSLMASRTKLQLVDLVSEEMQGSETTLIPPSSQLVSRRSGQSYRTGGVSIQEISHGTSESGYTTAFEHPRAGASVNSQSAGELMGFTSHEDAMGSAHRLEQASEKYVGEFVKKAKHGVINPETEEQRAESNQLKRRDSRRSSGGSGAKGPSDEMWVTDSAQGTPHPGATEGNAAVGNAIFKRNGRSLWNVIADIARLRWGSRAGSPDSSAKPAGRSSPNESVSSATWFSGREHDGSSDDNTKGDKVLPQEAPSLHQVEVGQTSPRSQSEYPGTTKLKQRSERHEGVVSSPSSTILEGGSVSNRMSSTSGNQIVGVDEEEGGNFEFRLPETALTEVPMKLPSRNLIRSPPIKESSESSLTEASSDQNFTVGEGRRYPRMDAGQNPLLFPGRNLRSPAVMEPPVPRPRMVSGSSSLREQVEQQQPLSAKSQEETGSVSADSALIQRKLQRNKQVVRDSFEEWEEAYKVEAERRTVDEIFMREALVEAKKAADTWEVPVGAVLVHDGKIIARGYNLVEELRDSTAHAEMICIREGSKALRSWRLADTTLYVTLEPCPMCAGAILQARVNTLVWGAPNKLLGADGSWIRLFPGGEGNGSEASEKPPPPVHPFHPKMTIRRGVLESECAQTMQQFFQLRRKKKDKNSDPPTPTDHHHHHLPKLLNKMHQVLPFFCL",
    "output": "Deaminates adenosines to inosines in tRNA-Arg(ACG). Exclusively involved in A-to-I editing of the prokaryote-type chloroplast-tRNA and not involved in C-to-U editing."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAMTAEVKDELSRLVVNSVSARRAEVASLLRFAGGLHIVSGRVVVEAEVDLGIIARRLRKDIYDLYGYNAVVHMLSASGIRKGTRYVVRVAKDGEALARQTGLLDLRGRPVRGLPAQVVGGSVADAEAAWRGAFLAHGSLTEPGRSSALEVSCPGPEAALALVGAARRLGVSAKAREVRGSDRVVVRDGEAIGALLTRMGAQDTRLTWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERALEILGDTVPDHLASAGKLRVEHRQASLEELGRLADPPMTKDAVAGRIRRLLSMADRKAKQDGIPDTESAVTPDLLEDA",
    "output": "Involved in cell division and chromosome segregation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVLEYQQREGKGSSSKSMPPDSSSTTIHTCSEAQTGEDKGLLDPHLSVLELLSKTGHSPSPMGQNLVTSIDISGNHNVNDSISGSWQAIQPLDLGASFIPERCSSQTTNGSILSSSDTSEEEQELLQAPAADIINIIKQGQEGANVVSPSHPFKQLQKIISLPLPGKEKTPFNEQDDDGDEDEAFEEDSVTITKSLTSSTNSFVMPKLSLTQKNPVFRLLILGRTGSSFYQSIPKEYQSLFELPKYHDSATFPQYTGIVIIFQELREMVSLLNRIVQYSQGKPVIPICQPGQVIQVKNVLKSFLRNKLVKLLFPPVVVTNKRDLKKMFQRLQDLSLEYGEDVNEEDNDDEAIHTKSRSYCRNKKAENSKKKSPKSNKKPKRKKQKFFTSWFTWGISITIGISFGCCVTYFVTAAYEHQTVKSLSLRPSILASLLSLDSSSDTINTPATASPSSTEQFLWFDKGTLQINFHSDGFIMKSLTIIKETWGKMNTFVLHALSKPLKFLENLNKSSEFSIDESNRILALGYILL",
    "output": "Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Promotes also autophagy-dependent peroxisome degradation (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKIIIFRVLTFFFVIFSVNVVAKEFTLDFSTAKTYVDSLNVIRSAIGTPLQTISSGGTSLLMIDSGTGDNLFAVDVRGIDPEEGRFNNLRLIVERNNLYVTGFVNRTNNVFYRFADFSHVTFPGTTAVTLSGDSSYTTLQRVAGISRTGMQINRHSLTTSYLDLMSHSGTSLTQSVARAMLRFVTVTAEALRFRQIQRGFRTTLDDLSGRSYVMTAEDVDLTLNWGRLSSVLPDYHGQDSVRVGRISFGSINAILGSVALILNCHHHASRVARMASDEFPSMCPADGRVRGITHNKILWDSSTLGAILMRRTISS",
    "output": "The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEMATIARPYAKAAFDFAVEKGELSQWAQMLTFCSEVAKNEDVAQLLDGAIASEQLAEIFISICGEQLNEFGQNFINVMAENGRLKVLPGVLEQFILLQHEFEKVIDADVTSAIELTEQQKADIGAKLEARLERKVKLNCSVDETLLAGVIIRAGDLVIDNSARGRLGRLSETLQS",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAVPASDGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVAGGMAGGSADAAGVLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTPKVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVVPAPSAS",
    "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKKHRIKKNDEFQTVFQKGKSTANRQFVVYQLDKEEQPNFRIGLSVSKKIGNAVVRNRIKRMIRQSITELKDEIDSGKDFVIIARKPCAEMTYEELKKSLIHVFKRSGMKRIKK",
    "output": "RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA",
    "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKCGSCGPGYKTPLDAMKGPREEILYLPCIYRNTGINKPDYLATVDVNPKSPKYSQVIHRLPMPNTNDELHHSGWNTCSSCYGDASKVRNKLILPCLISSRIYVVDVGTDPRAPRIHKTVEPYEVFWKCGLANLHTSHCLGCGEIMISSIGDPYGNGKGGFVLLDGETFEVKGNWEAEGEAAPFGYDFWYQPRHNVMISTEWGAPKAFALGFKMEEVQAGMYGHSLNVWDWTEHRRIQTIDLGEDGLIPLEIRFLHDPDAAQGLVGCALSSTVFRFYKEKDGKWAAEKVIKVPSKKVEGWALPEMPGLITDILISLDDRFLYFSNWLHGDIRQYDITDPRNPKLVGQIFLGGSILRGGPVTVLEDKDLECQPDPVIVKGKKVPGGPQMIQLSLDGKRLYVTNSLYSKWDKQFYPDMIKEGSVMLQIDVDTEKGGLKLNPNFLVDFGKEPGGPVLAHELRYPGGDCSSDIWV",
    "output": "Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria (By similarity). Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSVKVAINGFGRIGRNVLRAIIESGRTDIEVVAINDLGPVETNAHLFRFDSVHGRFPGEVKVAGDTIDVGRGPIKVTAVRNPAELPHKELGVDIALECTGIFTSRDKAAAHLAAGAKRVLVSAPADGADLTVVYGVNHEKLTNEHLVVSNASCTTNCLAPVAKVLNDAVGIEKGFMTTIHAYTGDQPTLDTMHKDLYRARAAAMSMIPTSTGAAKAVGLVLPELAGKLDGTSIRVPTPNVSVIDLKFVAKRATSKEEINEAIIAAASQQLKGILGFTDQPNVSIDFNHNPNSSTFHLDQTKVMEGTLVRVLSWYDNEWGFSNRMSDTAVAMGKLG",
    "output": "Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKVGMRERELKREKTVAKYAEKRAALKAIIANPNVSDEERWEAQMKLQKLPRDASPSRLRNRCQVTGRPHAVLRKFRLSRIKLREAAMRGDVPGLKKASW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF",
    "output": "Lipoamide dehydrogenase is an essential component of the alpha-ketoacid dehydrogenase complexes, namely the pyruvate dehydrogenase (PDH) complex, the branched-chain alpha-ketoacid dehydrogenase (BCKADH) complex, and likely also the 2-oxoglutarate dehydrogenase (ODH) complex. Catalyzes the reoxidation of dihydrolipoyl groups which are covalently attached to the lipoate acyltransferase components (E2) of the complexes (By similarity).; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MADHALNLDDFLSRFQLLRPQPSRHALNQRQAAVLVPIVRRPQPGLLLTQRSPLLRKHAGQVAFPGGAVDNTDATLIAAALREAQEEVAIPPEAVEVIGVLPPVDSVTGFQVTPVVGIIPPNLHYHASQDEVSAVFEMPLAEALRLGRYHPLDIHRRGNDHRVWLSWYQHYFVWGMTAGIIRELALQIGARP",
    "output": "Probably mediates the hydrolysis of some nucleoside diphosphate derivatives."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSHNTFGHLFRVTTWGESHGPALGCVVDGAPPRLPLKAEDIQQWLDRRKPGQSRFTTQRREPDAVKILSGTFVEDGIEMTTGTPISLMIENVDQRSKDYGDIVEKFRPGHADLTYFLKYGIRDYRGGGRSSARETAARVAAGAVARAMLPEMMIRGALVQMGPHKIDRANWDWNEVGNNPFWCPDAKAAAEWEIYLDSVRKAGSSCGAVIEIVASGVPAGLGSPIYGKLDAELASALMSINAVKGVEIGDGFGAAALSGEENADEMQSGPHGIEFSSNHAGGVLGGISTGQDVVARFAVKPTSSILSPRKTVTKGGDDTEIVTKGRHDPCVGIRAVPVGEAMMACVLADQLLRHRAQMGGSGRNE",
    "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSSCGACTCGAAAARLLTTSLTSAQRGISCGRIHVPVLGRLGTTLDAQALRRAPLRTFSETPAYFASKDGANKDGSGDGNKKSVTEGSSKKSGSGNSGKGGNQLRCPKCGDLCTHVETFVSSTRFVKCEKCHHFFVVLSEADSKKSIIKEPESAAEAVKLAFQQKPPPPPKKIYNYLDKYVVGQSFAKKVLSVAVYNHYKRIYNNIPANLRQQAEAEKQTSLTPRELEIRRREDEYRFTKLLQIAGISPHGNALGASMQQQVNQQMPQEKRGGEVLDSSQDDIKLEKSNILLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNVEKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLEGTIVNVPEKNSRKLRGETVQVDTTNVLFVASGAFNGLDRIISRRKNEKYLGFGTPSNLGKGRRAAAAADLANRSGESNTHQDIEEKDRLLRHVEARDLIEFGMIPEFVGRLPVVVPLHSLDEKTLVQILTEPRNAVIPQYQALFSMDKCELNVTEDALKAIARLALERKTGARGLRSIMEKLLLEPMFEVPNSDIVCVEVDKEVVEGKKEPGYIRAPSKESSEEEYDSGVEEDGWPRQADAANS",
    "output": "ATP-dependent specificity component of the Clp protease complex. Hydrolyzes ATP. Targets specific substrates for degradation by the Clp complex. Can perform chaperone functions in the absence of CLPP. Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure . ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis. Important for efficient erythropoiesis through up-regulation of heme biosynthesis (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSQQYEKKVERTEVVYGGDRRVEGSASASAEKTTNYTHTEIRAPMVNPLPPIISTGAAGLAQEIVGEGFTASATRISGAAATTQVLESQASREQAFKDQEKYSREQAAIARAHDKDLEKKTEEYRKTAEAEAEKIRKELEKQHARDVEFRKDLVESAIDRQKREVDLEAKYAKKELEHERELAMNALEQSKMATNVQVQMDTAAGTTVSGGTTVSEHTEVHDGKEKKSLGEKIKSLF",
    "output": "CAHS proteins are cytosolic heat soluble proteins that seem to contribute to the anhydrobiosis in tardigrades, but their specific mechanisms are yet to be identified . It is possible that protection during anhydrobiosis might occur via the stabilization of vitrifying small molecules such as sugars, but not via the direct glass transition of CAHS proteins themselves (Probable)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAPRGRPKKDLTMEDLTAKISQLTVENRELRKALGSTADPRDRPLTATEKEAQLTATVGALSAAAAKKIEARVRTIFSKVVTQKQVDDALKGLSLRIDVCMSDGGTAKPPPGANNRRRRGASTTRAGVDD",
    "output": "Plays a role in the inhibition of host innate immune system by targeting the CGAS enzymatic activity which is the principal cytosolic DNA sensor that detects invading viral DNA . Acts by inhibiting CGAS-DNA phase separation: directly binds double-stranded DNA (dsDNA) in a length dependent but sequence independent manner and is able to form DNA-induced phase separation in infected cells . DNA phase separation of ORF52 mediates disruption of liquid-like droplets in which CGAS is activated, thereby preventing CGAS activity . Targets also the HDP-RNP complex composed of DNA-PK subunits and paraspeckle proteins . This complex is a key nuclear regulator of DNA-mediated activation of innate immune response through the cGAS-STING pathway ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFGRRRRDLQA",
    "output": "CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MCEPGFARRREEVTGLNRITEKGLKDICKRDKLYQTPRLNDVLYLHFQGYQCIENLDEYTELKSLWLESNAISEIQNLTKLTKLKCLYLQNNLITKMENLEFNRELDTLNLSQNHIRKIENIGTDILPVLNTLNITSNYLTDSASLAALVECKTLSVLDLSNNRIDDILIVKIFEQMPSLKVLVLQGNPVVSRLPQYRKTLILACKELTYLDSRPVFPRDRACAEAWKREGYEGERKEVQRWNRAERRKTRESVNSTIRMRNRHLKPENQVPLLTSSDSEEEQKGISSAEKAQKRAEMEYGSVDTMWDEVSGESQASEHSTTSSTSAEDNESAGSQADHIAERISNRRVKPLEGRPKVLYDEAASGDVDSIVKLVTNKEENEQKDQNISEIEEQHKGKIVFIEEMNENQNASMGNQKAVSEAVETIGKPVAVDVNNTLSNSIVEPVNEQNNLASDQMEHLKGKRILIEKVDDIDPIKKELKYFDEAMQNKELKQTSELEELRDFTENLSSDVQEQAKDPSESDEEPTEEEMEVKSQLLKEQFQDRKQRLKEAIEERKTMQKNLEARKEDLNKSYNLFAKIMDDATDNVPKRVFGAGCDMPSKDWDKEECMQQLPLTSMEDSINGRPSSNDEDILTRPLTELTSAEAAEEICSQLDRKLAGEEAALRQLLCDLENENEILYSIETQIKYAESISVEDSQSQMVCASLLNDLISDVIYKDITEMGPNSYPLGPIESDEEYTYSEEPKLEKMVPPHLENPAGGKSLRECVDTFKEFFASKGNDKPRQESHTHLEKIRAAKALLKSKSLAEFSKDTPESLDAQLAKDEDRRKRHVAASAGRCFAKREKYDDTLEVVDNRLMVVKKDTGELEELPPPPELISDSESEKEVEEDDDAYDTAEETLQEYPRVPWTTPYKPKPRKAAEHLVNEAMQRILAEQFSELPDDTKENEPQEDEFFSLEAKETFGNLDSEFFQKLDLDKVTTANNAEAATECMRSYNELKACMKSGSTELQLTSEENEMLQEMLSSNEDLEAKHKSNDDPLVERDNELLNKMMQRMKEHEERARELQEQLEKEKEEENSGPIKLSMGEGSMLYQRWSPLSLTEIIDPQAEEGGRQAEEGGAQQEEGGAQSEERDDQAEGVPQAEEGVTQGEESVLQEEETHAENGVAQAEGRVLQSPEIYPIIGYEDIDDDDAASDFTTDYSSDDEVAVVVPPKISPAMLKAYYYDGFEEDMRMVRENEARTRRGLRAIMQKEKQMWKDNEEMAADMAPSPSPKEEHIPEVKTETETAKPTVETAKDKWAKIASRLNEFLDPEAMEQLESHEFGESDGEDDVDLTGLQNYDEESETECESALKETAEIGDSEKQENKTQDETLDPKDTEAITDVTLGIQRLKRQKLICQWEKIIPEDSKIGDGPTEKFLDQKAQDNPETTDERPENPKNFITLDYFVDTEPSESLEDTEATETPEVSTEQTLKTEQMEFNLDVLNDDGDVVIKEVTVEAQVTYQ",
    "output": "Cilium-specific protein required for cilia structures."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVEGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQSRLSSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELEPLDLEEDEAELGEQSGSAKTSVSSVTTPPPHGTRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHLFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQVQVLTSLRRNLSFWGGLETSQRGGGAVPQQQEHAM",
    "output": "Regulatory subunit of L-type calcium channels . Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit . Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKHPYPFGGQFMPEILMAPVQDLSNSWKSLQNHSDFKNELDSVLKNYAGRPTPLTEIKNFAKAIHGPRIFLKREDLLHTGAHKINNALGQCLLAKHLGKTRIIAETGAGQHGVATATACGCLGLECVIYMGAKDIERQKPNVDKMNLLGAEVISVNQGAQTLKDAVNEALRDWSKNYESTHYCLGSALGPSPYPEMVRNFQSVISLEVKSQLQEIGFSPDLLIACVGGGSNAIGFFHHFIPDTRVKLVGVEAGGLGIESGHHAARFATGRPGVLHGFYSYLLQDNEGQVLPTHSISAGLDYPAVGPDHAVLYESGRASYTVATDKAALEAFFLLSRLEGIIPALESSHALAELINIAPTLPKESVVVVNLSGRGDKDLEQITNLIKAGNNE",
    "output": "The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSKDEELLQNYCSILFTYKTIGISNLHLYYFRETEIKSLKQLINAEFAILQTCNRVEIYLYSDTNTLKEVNKIIQYLNNIHNEPIGNQARVLCGKDAAKHLFLVASGADSLSIGEYEILSQIRSTIDMFKKLGFSGKYLQIFFERAIKVGRKVREETSISKGKVGIYSLAIDEAKKRFNDFYDRRILVIGAGEMAQKITSMLHNEGAKDVTIMNRTIEKAKQLALKFGYNYEKLDLDKLGNFDVAFISIYHENLRLENKWNTLIVDITVPPLFTGNNVITLEELERISNLNFKAREEELAKINKLVEDGINELLYDYKKEIYTEFMSKIMKRIETIRENEILRAYKELEKLGINDQQAKEILDLMTRSIIKKSFQPLFDNIRSLIFNGENSINYINFLIDIFKDGNISGFETEKIKEKQVSERSSI",
    "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNHSPQSARPVSIMRRFLDSEAAGGITLMAAAALALIVANSPFAQTYFDALHLYIGPLSLAHWINDALMAKFFLLVGLEIKREMLDGQLASWPNRMLPGIAAAGGVILPAIIFAVLNHDNPAKLRGWAVPSATDIAFALGVLSLLGSRAPSSLKVFLATLAILDDLAAVVIIAIFYTAEISMPYLGAAFITAAVLFVMNRMGVVKLLPYLISAVILWFFVFNSGVHATVAGVVAALMIPLKPAPGRPDDMTSPLHKLEHTLAKPVAFIVVPIFGFANAGISFKGLEASVLGDTLTLGILLGLFLGKQFGVFGAAWLAIKTGLAEKPMGASWVQLYGVAILCGIGFTMSIFIGLLSFPSDLMQTETKIGVLSGSALSAICGYLLLRAAARPKRG",
    "output": "Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTSVRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEYLIRTAIDPDAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKILATVDVLQSLAVVAETNHYIRPQFNDNHVITIQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIISVPSQVESSSAVRQGQLSLFGDEEKAHEIRQALEAIDVMNMTPLQAMTTLYELKKLL",
    "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPRGSRSAASRPASRPAAPSAHPPAHPPPSAAAPAPAPSGQPGLMAQMATTAAGVAVGSAVGHVMGSALTGAFSGGSSEPSQPAVQQAPTPAAPQPLQMGPCAYEIRQFLDCSTTQSDLSLCEGFSEALKQCKYYHGLSSLP",
    "output": "May be involved in the maintenance of mitochondrial organization and mitochondrial cristae structure."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDNIQTFIKESDDFKSIINGLHEGLKEQLLAGLSGSARSVFTSALANETNKPIFLITHNLYQAQKVTDDLTSLLEDRSVLLYPVNELISSEIAVASPELRAQRLDVINRLTNGEAPIVVAPVAAIRRMLPPVEVWKSSQMLIQVGHDIEPDQLASRLVEVGYERSDMVSAPGEFSIRGGIIDIYPLTSENPVRIELFDTEVDSIRSFNSDDQRSIETLTSINIGPAKELIIRPEEKARAMEKIDSGLAASLKKLKADKQKEILHANISHDKERLSEGQTDQELVKYLSYFYEKPASLLDYTPDNTLLILDEVSRIHEMEEQLQKEEAEFITNLLEEGKILHDIRLSFSFQKIVAEQKRPLLYYSLFLRHVHHTSPQNIVNVSGRQMQSFHGQMNVLAGEMERFKKSNFTVVFLGANKERTQKLSSVLADYDIEAAMTDSKKALVQGQVYIMEGELQSGFELPLMKLAVITEEELFKNRVKKKPRKQKLTNAERIKSYSELQIGDYVVHINHGIGKYLGIETLEINGIHKDYLNIHYQGSDKLYVPVEQIDQVQKYVGSEGKEPKLYKLGGSEWKRVKKKVETSVQDIADDLIKLYAEREASKGYAFSPDHEMQREFESAFPYQETEDQLRSIHEIKKDMERERPMDRLLCGDVGYGKTEVAIRAAFKAIGDGKQVALLVPTTILAQQHYETIKERFQDYPINIGLLSRFRTRKEANETIKGLKNGTVDIVIGTHRLLSKDVVYKDLGLLIIDEEQRFGVTHKEKIKQIKANVDVLTLTATPIPRTLHMSMLGVRDLSVIETPPENRFPVQTYVVEYNGALVREAIERELARGGQVYFLYNRVEDIERKADEISMLVPDAKVAYAHGKMTENELETVMLSFLEGESDVLVSTTIIETGVDIPNVNTLIVFDADKMGLSQLYQLRGRVGRSNRVAYAYFTYRRDKVLTEVAEKRLQAIKEFTELGSGFKIAMRDLTIRGAGNLLGAQQHGFIDSVGFDLYSQMLKEAIEERKGDTAKTEQFETEIDVELDAYIPETYIQDGKQKIDMYKRFRSVATIEEKNELQDEMIDRFGNYPKEVEYLFTVAEMKVYARQERVELIKQDKDAVRLTISEEASAEIDGQKLFELGNQYGRQIGLGMEGKKLKISIQTKGRSADEWLDTVLGMLKGLKDVKKQTISST",
    "output": "Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTLRLLEDWCRGMDMNPRKALLVAGIPPTCGVADIEEALQAGLAPLGEHRLLGRMFRRDENKNVALIGLTVETGSALVPKEIPAKGGVWRVIFKPPDTDSDFLCRLNEFLKGEGMTMGELTRVLGNRNDPLGLDPGIMIPEIRAPMLAQALNEALKPTLQYLRYKKLSVFSGRDPPGPGEEEFESWMFHTSQVMKTWQVSDVEKRRRLIESLRGPAFEIIRVLKINNPFITVAECLKTLETIFGIIDNPRALQVKYLTTYQKTDEKLSAYVLRLEPLLQKLVQKGAIEKEVVNQARLDQVIAGAVHKSVRRELGLPEGSPAPGLLQLLTLIKDKEAEEEEVLLQAELEGYCT",
    "output": "Retrotransposon-derived protein that forms virion-like capsids . Acts as an effector of BAX during apoptosis: enriched at outer mitochondria membrane and associates with BAX upon induction of apoptosis, facilitating BAX-dependent mitochondrial outer membrane permeabilization and apoptosis (By similarity). Required for death receptor-dependent apoptosis (By similarity). When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation (By similarity). Also promotes autophagy: promotes phagophore closure via association with ATG8 proteins . Acts as an inhibitor of the NFE2L2/NRF2 pathway via interaction with SQSTM1: interaction promotes dissociation of SQSTM1 inclusion bodies that sequester KEAP1, relieving inactivation of the BCR(KEAP1) complex (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNQDQLKQMVGEAARDEVLKLPAGQVLGVGTGSTANYFIDALALHKGHFAGTVSSSNATTERLLKHGFKVLDPNDVQGLPAYVDGADEIDPAGHMIKGGGGVLTGEKIIASMAKQFICICDSSKQVPVLGNFALPVEIIPLSQGVVSRELEKFGGRVTLRLAKHTRADLNQTPSEPFVTDNGGWILDVAGLRIASPAQMEAQINQIAGVITVGLFAKEKANILLVSNAAGVERIQF",
    "output": "Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQRQILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYVTNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLEGTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTRKTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVSARFLGRDCRQMEKDAATIFENVKVVRDLEEVII",
    "output": "Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKLSSACAIALLAAQAAGASIKHRINGFTLTEHSDPAKRELLQKYVTWDDKSLFINGERIMIFSGEFHPFRLPVKELQLDIFQKVKALGFNCVSFYVDWALVEGKPGEYRADGIFDLEPFFDAASEAGIYLLARPGPYINAESSGGGFPGWLQRVNGTLRSSDKAYLDATDNYVSHVAATIAKYQITNGGPIILYQPENEYTSGCSGVEFPDPVYMQYVEDQARNAGVVIPLINNDASASGNNAPGTGKGAVDIYGHDSYPLGFDCANPTVWPSGDLPTNFRTLHLEQSPTTPYAIVEFQGGSYDPWGGPGFAACSELLNNEFERVFYKNDFSFQIAIMNLYMIFGGTNWGNLGYPNGYTSYDYGSAVTESRNITREKYSELKLLGNFAKVSPGYLTASPGNLTTSGYADTTDLTVTPLLGNSTGSFFVVRHSDYSSEESTSYKLRLPTSAGSVTIPQLGGTLTLNGRDSKIHVTDHNVSGTNIIYSTAEVFTWKKFADGKVLVLYGGAGEHHELAISTKSNVTVIEGSESGISSKQTSSSVVVGWDVSTTRRIIQVGDLKILLLDRNSAYNYWVPQLATDGTSPGFSTPEKVASSIIVKAGYLVRTAYLKGSGLYLTADFNATTSVEVIGVPSTAKNLFINGDKTSHTVDKNGIWSATVDYNAPDISLPSLKDLDWKYVDTLPEIQSSYDDSLWPAADLKQTKNTLRSLTTPTSLYSSDYGFHTGYLLYRGHFTATGNESTFAIDTQGGSAFGSSVWLNGTYLGSWTGLYANSDYNATYNLPQLQAGKTYVITVVIDNMGLEENWTVGEDLMKSPRGISTSCLPDGQAAPISWKLTGNLGGEDYEDKVRGPLNEGGLYAERQGFHQPEPPSQNWKSSSPLEGLSEAGIGFYSASFDLDLPKDGMSHCSSTSVTALRHPRTACRSTSTDIVCEIHKQHRTSDQLPCPRGNPELSRNELVGGDPVALDSAGGKLESLELSYTTPVLTALGEVESVDQPKYKKRKGAY",
    "output": "Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEFDTIAAISTPPGEGAIAIIRLSGPEAIQIADRIFYAKNSLSEAESHTIHYGHIKEDGEVIEEVMVTVMRAPRTFTREDVVEINAHGGIVSVNRVLQLLLRNGANLAEPGEFTKRAFLNGRIDLSQAEAVMDLIRAKTDRAMGVAIRQMDGNLSRLIRNLRQEILDALAQVEVNIDYPEYDDVEEMTQRMLLEKTELVRASVEQLLQTASQGKILREGLATAIIGRPNVGKSSLLNQLIQEEKAIVTDIAGTTRDIIEEYVNVRGVPLRLIDTAGIRETEDIVEKIGVERSRKALADADFILLVLNQNEELTVEDEALFEAAAGHNYVVVLNKTDLETKLDIDRVRELAGENPIVSTSLVNDEGLEALEEAIKTLFFAGDIDAGDATYVSNVRHIALLHQALEALNGVTTGIQLGMPVDIVQIDMTRAWDLLGEITGDSVQDELLDQLFNQFCLGK",
    "output": "Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTEEPLSAAWLTERTIYLLTLLREKRPLVHNITNLVVTNTTANALLALGASPAMVEGVEEVDSFARMADSLVINLGTMSSPRAAAMRLAMAAARQAGKPVVLDPVAVGALRYRTELARDLLEAKPHIVRGNASEIIALAGDGGGGRGVDSLVSSTAALEAASILARRTGGAVAVTGATDYVTDGTRLIGIANGHPMMTRVTGLGCTATALIGAFAAVEPDPLVAACAGLCATGLAGELAAIRADGPGSLQVEFLDALYALDSAILRDAARWVLP",
    "output": "Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPLSLWRLAIGSSRRHSLLKITSTRVLPVPRPYSTYSNNKKVIMPGEDQPAAAPAAAPAAQDAPGAPAPKKNDKKEKAKADKAAKFAAKQAAAKAKQPAAQSAPKEKKEKTPALPPYEDSTPAGEKKVIQSFEHPHFSAYNPSAVEAAWYQWWEKAGYFKPESCRKPSAGKFVIPLPPPNVTGALHCGHALANSLQDTLIRWYRMKGYETLWVPGCDHAGISTQSVVEKMLWKKEKKIRQELGREKFTDLVWEWKGEYHQRINNAQKLMGGSMDWSREAFTMDKNLTAATMETFCRLHDEGLIYRSNRLVNWCTHLNTALSGLEVETKEITGRTLLDVPGYDKKVEFGVLTHFKYQIDGSEETIEVATTRPETMLGDTGIAVNPEDPRYTHLVGKFARHPFVDRLLPIVTDNYVDKEFGTGAVKLTPAHDFNDYQLGQRHNLEFINILNENGTLNDNAGPFKGQKRFDARYTVVEELTKLGLFVKKEPNPMKIPLCEKSKDVIEPMMTEQWWVRMKEMGEAALQVVEEGKVKISPESATKSYKRWLADIQDWCISRQLWWGHRIPAYRVIFEGEEGQRENEKSEWVVGRTQEEAQAKAEAKFAGRKFTLEQDPDCLDTWFSSGLWPMAILGWPNTENLDFKKFFPTSMLETGWDILFFWVSRMIMLSLKMTGEVPFTEVYCHSLIRDSEGRKMSKSLGNVIDPLDIIRGIELEDLHAKLLVGNLKEEEVARATKYQKTAFPGGIPECGADAMRFTLLSYTTGGGDINFDIRVMHAYRRFCNKIWQASKYVLGKLPQDFMPKGELDTANFSVPEKWILHRMNVAVKGMNEALEAREFSRATKVAYQFFYDELCDVFIENSKGILSDGTPEEQQSVQQTLYHALDVALRLLHPIMPYITEELWQRLPRKQGDGETIMLAPYPAFESQLEFATEAEDYELGLKCAGGIRSLAADYNIKSDGRAFIKATTADSLATVSAQLAAIRTLCGKGVKEVNVLGADEELPRGCAVYVINAEITVLLQVGGSISDIDAEIKKITTKLQKTDLTIKKQQELLSKDGFEKVSEAVQESEKQKLADAQAAKENYQRTLEEFSKLKI",
    "output": "May have a second function in addition to protein synthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MELLNLKKQGIDIKEQIPLSRYTFTKTGGEAEYLAFPKTTDEVEKLVKVTQENKIPLTIIGNASNLIIRDGGIDGLVIILTELKNIEVNGNEVTADAGATIVDTAFTAANHGLSGMEFAAGIPGSIGGGVFMNAGAYGGEMQEAVKSVNVLTRAGEYKTYSNQEMDFSYRHSIIQENGDIVLSATFSLKPGNKLQILDHMDYLNALRRYKQPLEYPSCGSVFKRPKGHFVGPMIIKAGLQGKQIGGAQDSTKHAGFIVNKGGATATDYLDLIHLIQKVIKEKYDIDLHTEVRIIGKEN",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MERKFLTDLGLNPDQVNSIMAQYGKDMQEYEGLEAERDALKKTSSELSSKIEDLKANSANVEELTKQIEKLKSDNENATKQLNAQKLDFAVTSTIKDFGAKNAKAVKALLNHDDIRFDSKGNLIGLEDQLKSLKDSDSYLFAEDKPAGKPIQAFPTGNPVAGGKDVSLHQKIAQRLKG",
    "output": "Scaffolding protein involved in the icosahedric procapsid assembly. Coassembles with the capsid proteins to form the procapsid, in which the scaffolding protein is found within the external shell of icosahedrally arranged capsid protein subunits. In a subsequent step the scaffolding protein molecules are released from the procapsid."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSRPEELAPPEIFYNDSEAHKYTGSTRVQHIQAKMTLRALELLNLQPCSFILDIGCGSGLSGEILTQEGDHVWCGLDISPSMLATGLSRELEGDLMLQDMGTGIPFRAGSFDAAISISAIQWLCNADTSYNDPKQRLMRFFNTLYAALKKGGKFVAQFYPKNDDQVDDILQSAKVAGFSGGLVVDDPESKKNKKYYLVLSSGAPPQGEEQVNLDGVTMDEENVNLKKQLRQRLKGGKDKESAKSFILRKKELMKRRGRKVAKDSKFTGRKRRHRF",
    "output": "S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of guanine 1575 (m7G1575) in 18S rRNA. Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity. Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity. Required for efficient cleavage of the primary 35S precursor rRNA at site A2. Involved in positioning the proximal bud pole signal."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPLSYQHFRKLLLLDDEAGPLEEELPRLADEGLNRRVAEDLNLQLPNVSIPWTHKVGNFTGLYSSTLPVFNPNWQTPSFPDIHLHQDIINKCEQFVGPLTVNEKRRLKLSMPARFYPNSTKYLPLEKGIKPYYPDNVVNHYFQTRHYLHTLWQAGILYKRETTRSASFCGSPYSWEQELQHGAESFHQQSAGIFSRAPVGSSIQSKHQQSRLGLQPQKGLLARGNEGRSWSVRSRVHPTTWRSFGVEPSSSGHTNNFASKSASCLHQSAVRKAAYPTFSTTKRHSSSGHAVELHNISSSSAGSQSKGPVFSCWWLQFRNIEPCSEYCLSHLVSLLDDWGPCTEHGEHHIRIPRTPARVTGGVFLVDKNPHNTAESRLVVDFSQFSRGSTRVPWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARLSSNSRILDHQHGTMQNLHDSCSRNLFDSLMLLYKTFGRKLHLYSHPIIMGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLYTAVTNFLLSLGIHLNPNKTKRWGYSLHFMGYVIGSWGTLPQEHIVQKIKNCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQAKQAFTFSPTYKAFLSQQYSTLYPVARQRSGLCQVFADATPTGWGLVMGHQRMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLIRLLFQPTTGRTSLYAVSPSVPSHLPVRVHFASPLHVAWRPP",
    "output": "Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids. This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode. Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid. Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein. Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome. After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA). The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSLQSIKYSRGSLEILDQLLLPGQSKYVVVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVEINPEDFENKKSLRQEIEGKLNYLVSARPTAVNMKIAADELITLANELYKDEATDVTQMKHRFLDATEAMLKKDIADNRAIGANGAQAILQRVAKAGKTPAGSTGSVRVLTHCNTGSLATAGYGTALGVVRQLAELGKLEHVYCTETRPYNQGARLTAYELVHEKFPATLVLDSMVAALLRAKNVAAVVVGADRVASNGDTANKIGTYQIAVVAKHHDVPFYVAAPLTSIDLAIPGGDHIIIEERPDREMTHVGEHRIAAPGINCWNPAFDVTPASLITGIITERGVFKPAELKEAITKLLES",
    "output": "Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNRVAVVVLGDIGRSPRMQYHSMSLSKLENTKVTLIGYRESEPHPQIVNNDSITIEPLKPFPISMSNSFKKIPLISIFMWPLLAICKVLFQIIQLMYVLLVKVPSPLNTILVQSPPAIPTIFVMQIVCWIRGVHLVIDWHNLGYTLLKLSLSKSDNHPIIRLAKFIERYFAKNAYAHLFVTNEMKIQLVRDWNLKGKTFVFHDKASPIFKSLTDREQEEFLKTFINKYSIKGEDKVYIESVISKKSIRNPKQQTSIIISSTSWTQDEDFSILLDAIVKYDIEHAINNNNNKVEEAQDESVVLAENLLFIITGKGPQKEYYQEKINSLSLKKSRIITVWLDSEDYPKLLACCDLGVSLHNSSSGIDLPMKVVDMFGCCLPVLAIDFKCIGELVKVNYNGFLFKDSDQLHQLLNQLFTHPTNNNTITNTNNNKNLILEKMRKNLTKDRETDTWESNWLTIKPLFIPSSSSSSSSSSSSSSSSSSSSSSNSKSKKD",
    "output": "Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVQLNQNFINTIAQELPAHLSMDDFIAACSRPLRRSIRVNTLKISSEDFKQLMLPKGWTFEPIPWCEDGFWISYDEEEQLGNALEHIQGLFYIQEASSMLPPTALFTPNADWQCVLDLASAPGSKTTQMAALMNNQGLLVANEYSASRVKVLHANVLRMGASHCALTHFDGRVFGEYLYESFDAVLIDAPCGGEGTVRKDADALKSWSLDEVLEISETQKALIESAFLALKPGGSLVYSTCTLNRHENQGVCEYLQQTYGDAVQFESLSQLFDGAEKATTPEGFLHVWPQIYDSEGFFVAKLTKTRSVPRLQPEPKLQKNFPFTEASAKQAKAIQAYFADDLGIKLPDDLIMVRDDEFWLFPHEFRDFIGKMRFQRIGVKLADHSKHGFKVRHEAIIALAGKALTAGAANGAKVVDVSDEQAKEYLMGRDIPLDTAGKAQGEVIVCYGGAPLGMAKHLGNKLKNSLPRDLVKDKVLLLPPQA",
    "output": "Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPDLQELWNYLQEKFQTDLTTVGFNAWIKTAKPLAFRANELLIEVPSVLHKEYWENNLATKVVEGAYEFAEIELTPIFVLPGESDNLTPLEPEEEHVLTKAETPTFLRETHLNSKYTFDTFVTGKGNQMAHAAALVVSEEPGVLYNPLFLYGGVGLGKTHLMQAIGHQLLESKPETNVKYVTSEAFANDFINSIQTKNQEKFRQEYRNVDLLLVDDIQFFADKEGTQEEFFHTFNDLYNDKKQIVLTSDRLPNEIPKLQERLVSRFKWGLPVDITPPDLETRIAILRNKADAEHLEIPEDTLSYIAGQIDSNVRELEGALVRVQAYATMQNAEITTSLAADALKGLKLNGKSSQLSIAKIQSVVAKYYSLTVADLKGRKRVKEIVLPRQIAMYLAREMTDSSLPKIGQEFGGKDHTTVMHAHERISQSLTTDQNLKDAILDLKNTMKS",
    "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKCPRCGKQEIRVLESRSAEGGQSVRRRRECMSCGYRFTTYERIEFMPIMVIKRDGSRESFNRNKILQGVMRACQKTQVSVKQMEELVNEIEEKLQLEDVQEVTTLRIGEMVLERLQRLSEVAYVRFASVYRKFQGIKDFVTELEQLERLETHLRRDLERPLRNSPPSESESTASPDWVGGIPQLLDQNDTSSNLSEIPK",
    "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQELILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRMVKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRGATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSDTDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRGPGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLKESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRALVRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIIHIKKHQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQLPAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQPQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLSPPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFGFSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST",
    "output": "Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSRGNELVFKAKKTSEKISENIHIFANDPSLAFFRVQEHVRKVTPAIFEKRDEVFQLQNNLQGHCYDMEYGIQALRTIEKSESIFENIQEMIKASIFLKQQLKYEESRKKVKKDSTKSSVYKRFSAHLALDLPDLPDFGGVMRETSQRMENMIGPGTATGRTEAQAATSSNPGELQRSYTTLH",
    "output": "May participate in the coupling of lysosomes to microtubule plus-end-directed kinesin motor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKMVKSIAAGLTAAAAIGAAAAGVTSIMAGGPVVYQMQPVVFGAPLPLDPASAPDVPTAAQLTSLLNSLADPNVSFANKGSLVEGGIGGTEARIADHKLKKAAEHGDLPLSFSVTNIQPAAAGSATADVSVSGPKLSSPVTRNVTFVNQGGWMLSRASAMELLQAAGN",
    "output": "May play a role in the development of protective immune responses."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPTAANLLAIMPFPDIDPIAFSIGPLAIHWYGLAYVAGILLGWAYARRLAANESLWPGNASPMTRTQLDDFIVWAALGVVLGGRLGYIFFYDLPAVLRSPVRALEIWNGGMSFHGGLTGTTIAMIIFARRNGIPIWSLFDIVATVVPFGLFFGRIANFINGELWGRLTDVPWAVVFPTGGPFARHPSQLYEAGLEGIVLLLVLAALVYGMRALKSPGFITGVFVCGYALSRIFVEFFREPDAQLGYLLGTNWLTMGMVLSSPMILLGLWAMLRARRQAALQL",
    "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEIDVRVQIDRKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIESVTFDRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNISLDLGNNAEAVILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRSKPEMLIELFRIEVPEIGEEVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERIDIVLWDDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGWELNVMTVDDLQAKHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKELLEIEGLDEPTVEALRERAKNALATIAQAQEESLGDNKPADDLLNLEGVDRDLAFKLAARGVCTLEDLAEQGIDDLADIEGLTDEKAGALIMAARNICWFGDEA",
    "output": "Participates in both transcription termination and antitermination."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MANPKPQAKKKIKKNIPKGIAHIHSTFNNTIVTVSDEKGNVLSWSSAGAIGFKGSKKSTPYAAQLISEAAAKGAMDNGVKTVSVEVKGPGPGRDAAIRALQMAGLEITSIKDTTPIPHNGVRPRKRPRG",
    "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEAQNQEVAALVEKIAGLHAAISKLPSLSPSAEVDALFTDLVTACVPASPVDVAKLGPEAQAMREELIRLCSAAEGHLEAHYADMLAAFDNPLDHLARFPYYGNYVNLSKLEYDLLVRYVPGIAPTRVAFVGSGPLPFSSLVLAAHHLPDAVFDNYDRCGAANERARRLFRGADEGLGARMAFHTADVATLTGELGAYDVVFLAALVGMAAEEKAGVIAHLGAHMADGAALVVSARHGARGFLYPIVDLEDIRRGGFDVLAVYHPDDEVINSVIVARKADPRRGGGLAGARGAVPVVSPPCKCCKMEAAAGAFQKAEEFAAKRLSV",
    "output": "Synthesizes nicotianamine, a polyamine that is the first intermediate in the synthesis of the phytosiderophores of the mugineic acid type found in gramineae which serve as a sensor for the physiological iron status within the plant, and/or might be involved in the transport of iron."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRPSNRTPEQNREIKITRHYTDYAEGSVLIEMGNTKVLCNASVSGSVPRFLKGKGKGWVTAEYAMLPRATHIRNMREAAKGKQGGRTLEIQRLIARSLRAAVDLNALGENMITVDCDVIQADGGTRTAAITGGCIALADALNWMVKKGKLKKSPLKQMIAAVSVGIYQGTPVCDLDYAEDSNAETDTNVVMTESGGLIEIQATAEDGAFSHEQLLSMLSLAKGGIEALVVEQKKALNAE",
    "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHIGQMLLTRADMEDRERFLNARDTLRALLDNHIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQQGLFTADPRSNPQAELIKDVYGVDDALRSIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIASGSKPGVIGDVMEGISVGTRFHAQASPLENRKRWIFGAPPAGEITVDEGATAAMLERGSSLLPKGIKSVTGNFSRGEVIRICNLQGRDIAHGVSRYNSDALRRIAGHHSQQIDAILGYEYGPVAVHRDDMITR",
    "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPRYRLLVEYDGRPYAGFQAQATLPSVQGAIEAAVKAFCGQEVRIAAAGRTDTGVHATGQVVHVDLDKDWPAQTVFNALNAHLTREAVSILSAEVAEEGWHARFSANERRYLYRILNRRAPPALDKGRVWHMKKDLDHEAMHAAAQHLIGLHDFTTFRDMHCQSKSPVKTLDVARVRRVGEEIHLDFEARSFLHRQVRSMTGTLVEVGAGRWTVDDVKAALEARDRRECGPVAPADGLYLVGVGYGD",
    "output": "Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKTLLLTLVVVTIVCLDLGNSLKCYVSREGKTQTCPEGEKLCEKYAVSYFHDGRWRYRYECTSACHRGPYNVCCSTDLCNK",
    "output": "Snake venom neurotoxin that blocks neuromuscular transmission on both avian and mouse nerve-muscle preparations, presenting a postsynaptic action through the nicotinic acetylcholine receptor (nAChR). Reversibly inhibits twitches in mouse phrenic nerve diaphragm and irreversibly in chick biventer cervicis muscle. Has no cytotoxic activity towards C2C12 cells up to 180 ug/ml."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVGRRALIVLAHSERTSFNYAMKEAAVAALKKKGWEVVESDLYAMNFNPIISRKDITGKLKDPENFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERVFVGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK",
    "output": "Flavin-containing quinone reductase that catalyzes two-electron reduction of quinones to hydroquinones using either NADH or NADPH as electron donors. In a ping-pong kinetic mechanism, the electrons are sequentially transferred from NAD(P)H to flavin cofactor and then from reduced flavin to the quinone, bypassing the formation of semiquinone and reactive oxygen species (By similarity). Regulates cellular redox state primarily through quinone detoxification. Reduces components of plasma membrane redox system such as coenzyme Q and vitamin quinones, producing antioxidant hydroquinone forms. In the process may function as superoxide scavenger to prevent hydroquinone oxidation and facilitate excretion (By similarity). Alternatively, can activate quinones and their derivatives by generating redox reactive hydroquinones with DNA cross-linking antitumor potential (By similarity). Acts as a gatekeeper of the core 20S proteasome known to degrade proteins with unstructured regions. Upon oxidative stress, interacts with tumor suppressors TP53 and TP73 in a NADH-dependent way and inhibits their ubiquitin-independent degradation by the 20S proteasome (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAATAMRMIISIIFISTYMTHITLCQNITEEFYQSTCSAVSRGYLSALRTGWYTSVVTIELSKIQKNVCKSTDSKVKLIKQELERYNNAVIELQSLMQNEPASFSRAKRGIPELIHYTRNSTKRFYGLMGKKRKRRFLGFLLGIGSAIASGVAVSKVLHLEGEVNKIKNALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKELLPKVNNHDCRISNIETVIEFQQKNNRLLEIAREFSVNAGITTPLSTYMLTNSELLSLINDMPITNDQKKLMSSNVQIVRQQSYSIMSVVKEEVIAYVVQLPIYGVIDTPCWKLHTSPLCTTDNKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPTDVNLCNTDIFNTKYDCKIMTSKTDISSSVITSIGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKLEGKALYIKGEPIINYYDPLVFPSDEFDASIAQVNAKINQSLAFIRRSDELLHSVDVGKSTTNVVITTIIIVIVVVILMLIAVGLLFYCKTRSTPIMLGKDQLSGINNLSFSK",
    "output": "[Fusion glycoprotein F0]: Inactive precursor that is cleaved at two sites by a furin-like protease to give rise to the mature F1 and F2 fusion glycoproteins.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNRAFCLLARSRRFPRVPSAGAVLSGEAATLPRCAPNVVRMASQNSFRIEYDTFGELKVPTDKYYGAQTVRSTMNFKIGGATERMPIPVIKAFGILKRAAAEVNQEYGLDPKIASAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVNKSQSSNDTFPTAMHIAAALEVHQVLLPGLQKLHDALSAKSKEFAQVIKIGRTHTQDAVPLTLGQEFSGYVQQVQYAMERIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK",
    "output": "Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (By similarity). Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable).; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPELYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKATTAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK",
    "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDFGSVMNQAATPCSPAVNYELPSPGQSITKQVDTPDATRSPRGGQAHRKASRSMSVTAAMESSCELDLVYITERIIAVSYPSTAEEQSFRSNLREVAHMLKSKHGDNYVLFNLSERRHDISKLHPKVLDFGWPDLHTPALEKICSICKAMDTWLNAAAHNVVVLHNKGNRGRLGVVVAAYMHYSNISASADQALDRFAMKRFYEDKVVPVGQPSQKRYIHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLKIYQAMQPVYTSGIYNVQGDSQTGICITIEPGLLLKGDILLKCYHKKFRSPTRDVIFRVQFHTCAVHDLDIVFGKEDLDEAFRDERFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYENFNIQREDSTEGTWAEPALPGKHLEKEVGHTQGPLDGSLYAKVKKKDSLHGSIGAVNAARLPLSAAPNHVEHTLSVSSDSGNSTASTKTDRTDEPGAPGAPTGHAVLSPEEKRELDRLLVGFGLESAPPMHNHAPGPAPARLPAGPGRHVVPAQVHVNGAGTPLLAERETDILDDELPNQDGHSVGSLGTLSSLDGTTTASEAGFHEAPRVGSLSSLPNGPASYNGAEKMLKEGLYEAEPLSNGAYPYSNQNTLMGHHLRDPLAHLRPSASAQEHLAGYPQRQPASTSPAWLQPPVPQPYLYGYDLPSAHRSQSFPAVGTAKYEANLALPQAPARSTSSREAVQRGLNSWQQQGGSRPPSQLHDGGLESHSPSLSSCSPQPSPLQPMPPHSHSMPEFPRAPSRREIEQSIEALDVLMLDLAPSVHKSQSVPSAATRQDKPAAMLSSLSAQPLSGHYAQPTPQVVQPRSFGTSVGTDPLAKAYSPGPLVPAARSTAEPDYTVHEYRETYTPYSYQPVPEPRSYGSAPASILPLSASYSPAGSQQLLVSSPPSPTAPAQSQLPHKGLESYEDLSRSGEEPLNLEGLVAHRVAGVQSREKSPEESTVPARRRTPSDSHYEKSSPEPGSPRSPTVLSPEVVSTIAANPGGRPKEPHLHSYKEAFEEMESASPSSLTSGGVRSPPGLAKTPLSALGLKPHNPADILLHPVGELEGEAGADSEEEPRSYVESVARTATTGRAGNLPAAQPVGLEVPARNGAFGNSFTVPSPVSTSSPIHSVDGASLRSYPSEGSPHGTVTPPHAVAETAYRSPMVSQTPSAHSSYQTSSPSSFQAGTLGSPYASPDYPDGRAGFQPDPQARQQPQVSVVGVHALPGSPRTLHRTVATNTPPSPGFGRRAANPAVASVPGSPGLGRHTVSPHAPPGSPSLARHQMAAVPPGSPMYGYSSPEERRPTLSRQSSASGYQPPSTPSFPVSPAYYPGTSTPHSSSPDSAAYRQGSPTPQPALPEKRRMSAGERSNSLPNYATVNGKASSPLSSGMSSPSSGSAVAFSHTLPDFSKFSMPDISPETRANVKFVQDTSKYWYKPDISREQAIALLKDREPGAFIIRDSHSFRGAYGLAMKVASPPPTVMQQNKKGDITNELVRHFLIETSPRGVKLKGCPNEPNFGCLSALVYQHSIMPLALPCKLVIPDRDPMEEKKDAASTTNSATDLLKQGAACNVLFINSVEMESLTGPQAISKAVAETLVADPTPTATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWTKTDGSGPAKLFGFVARKQGSTTDNVCHLFAELDPDQPAAAIVNFVSRVMLGSGQKR",
    "output": "May act as a protein phosphatase and/or a lipid phosphatase. Involved in fibrillar adhesion formation. Plays a role in cell polarization and migration. May be involved in cartilage development and in linking signal transduction pathways to the cytoskeleton."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNKKKKYVHTKQFNSHDCGLACISSILKFHNLNYGIDFLLDLIGDKEGYSLRDLIVIFKKMGIKTRPLELQENKTFEALKQIKLPCIALLEGEEYGHYITIYEIRNNYLLVSDPDKDKITKIKKEDFESKFTNFILEIDKESIPEKEKDQKKHSYFFKDILFRNKLIVFVILLTSLFVVGLAVAGSFYIKFLVDLIIPRSLRESLITITLIFISMVLIRCIFDFVRSYLIIKLSYKVDKEMSNVYFNKVTKLPINFFENREDGEVISRFNDGIYIKDFFSANFVTAIIDIILILGLGVILYRTNNILFLTIILPILLLSCLAILFFDHLKKKNQKLMEDKAKSTSLLINFLKNMTTVYSLNKTSFFLEKFHLTYDKQLNSTFSVAKAVISNEILKGLIQNSFTIIILWVGTRQVLNDSMSLGTLLFINTLAAFLLSSLDRILSMQSDLQQAHVASIRFFDVVNYPVQQDSNENLTELDFIQNIKTVNLNIGADPMRYIVEDINLILDRKDKVLIIGESGTGKSTFAKSLSKLYKVPDKSIYLNGLDINRYDHLSIRKRIVYIDENPFLFKGTIKENLCMGEIFDQNEIENACIMSQCHEFICNLDKQYSYKLSENGSNLSTGQKQRLALARAILHQPQVLILDESLSNIDPDNTKLIYETLHRMDCLIILITHNDPSNFKYNKKLVFRNNRIIESSYSENKEYSI",
    "output": "SunT (TC 3.A.1.112.4) is required for production of the lantibiotic sublancin-168, probably by both processing the signal peptide and exporting the resulting mature lantibiotic."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKNRTLGSVFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLWALMCYTALLLLEVYQHVPADTGLGTLAKRYLGRYGQWLTGFSMMFLMYALTAAYISGAGELLASSISDWTGISMSATAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVVMLVLLLPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMDGNIRKLRWVFIIGSAIPLVAYIFWQVATLGSIDSTTFMGLLANHAGLNGLLQALREMVASPHVELAVHLFADLALATSFLGVALGLFDYLADLFQRSNTVGGRLQTGAITFLPPLAFALFYPRGFVMALGYAGVALAVLALIIPSLLTWQSRKHNPQAGYRVKGGRPALVVVFLCGIAVIGVQFLIAAGLLPEVG",
    "output": "Transports tyrosine across the cytoplasmic membrane. The transport system is energized by the proton motive force."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGSLSIWHWLIVLLIVALVFGTKKLRNIGSDLGGAVKGFKEGMKDGETPEGQQRDQLSRTNTVDVDAKEKAPHSGDSR",
    "output": "Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAPKAAEKKPAGKKPAEKAPAEKLPKAEKKITKEGGSEKKKKKSKKNIETYKIYIFKVLKQVHPDIGISGKAMGIMNSFINDIFEKLAQESSRLARYNKKPTITSREIQTAVRLVLPGELSKHAVSEGTKAVTKFTSS",
    "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "METIAKHLDVCQEQLLELYEENSNNLTKHIQHWKCIRYECVLLHKAKQMGLNHIGMQVVPALTVSQTKGHQAIEMQMTLETLLNSDYGMEPWTLQDTSREMWLTAPKYCFKKQGQTVEVKYDCNADNIMEYVSWKYIYVHDTDKWVKVTGHIDYKGLYYVHGGHKTYYTNFEKEAKKYGNSLQWEVCIGSSVICSPASISSTVQDVSIAGPASHTSSSTTTTLAQASPALPTCTSEERVDPPPCKRPRGPTTNTNNARDTVSVRHSDSVDSTNNNIYPNSYNSNKGRDNNFCTATPVVQLQGDPNCLKCLRYRLHAKHKTLFVAASSTWRWTCSDTSSKHALVTLTYVNEEQREQFLNTVRLPPTVTYKVGYMSLQLL",
    "output": "Plays a role in the initiation of viral DNA replication. A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity. Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA. E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome. Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box. Repression occurs by sterically hindering the assembly of the transcription initiation complex."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTQYIPDTQRPIGLFDSGEGGLTVARAVADLLPQENLIYACDTAHFPYGPRPLAEVRAFFRRFMEFFVEQNCKLVIVACNTATAAAIDLLLADAFPIPALGVVQPGAAMAAEASVTGRIGVAATQGTCDSGIYPQTIRLFRPDAYVVQQACPILVIRAEEGVISGPEVRREVERCLAPILAERVDTLVLGCTHFPHMAKVIQDVVGPAVRLVDPGKATAVQVADLLRRRGLLNPGPGPGQRRAFTTGDPQRFLEVACRLWPGGVDAAAHIHLWSQQE",
    "output": "Provides the (R)-glutamate required for cell wall biosynthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSIIINNVSKQFGDFTALKDINLEVPDGKLVALLGPSGSGKSTLLRAIAGLEEPDQGQIIINGQDATHVDIRKRNIGFVFQHYALFKHLTIRQNIAFGLEIRKHPPAKTKERVEELLSLIQLEGLGNRYPSQLSGGQRQRVALARALAVQPQVLLLDEPFGALDAKVRKELRAWLRKLHDEVHLTSVFVTHDQEEAMEVADEIVVMSNGKIEQVGTAEEIYEHPASPFVMGFIGEVNVLPRNASLFNYHAFEPHSSNNGHQEPVFVRPHDFELLTEADDASVAGTIKRVIHLGSEIQVEVLLMDNTAVLAYLNREQGQQLNPKAGKKVFIKPRVAKVFAGASSAASTHFIYGTGI",
    "output": "Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MACSTLSKSPKDKIDPRDLLIPLILFLSLKGARSAAPGSSPHQVYNITWEVTNGDRETVWAISGNHPLWTWWPVLTPDLCMLALSGPPHWGLEYQAPYSSPPGPPCCSGSSGNVAGCARDCNEPLTSLTPRCNTAWNRLKLDQVTHKSSEGFYVCPGSHRPREAKSCGGPDSFYCASWGCETTGRVYWKPSSSWDYITVDNNLTSNQAVQVCKDNKWCNPLAIRFTNAGKQVTSWTTGHYWGLRLYVSGQDPGLTFGIRLSYQNLGPRIPIGPNPVLADQLSFPLPNPLPKPAKSPPASSSTPTLISPSPTPTQPPPAGTGDRLLNLVQGAYQALNLTNPDKTQECWLCLVSGPPYYEGVAVLGTYSNHTSAPANCSVASQHKLTLSEVTGRGLCIGTVPKTHQALCNTTLKAGKGSYYLVAPTGTMWACNTGLTPCLSATVLNRTTDYCVLVELWPRVTYHPPSYVYSQFEKSHRHKREPVSLTLALLLGGLTMGGIAAGVGTGTTALVATQQFQQLHAAVQDDLKEVEKSITNLEKSLTSLSEVVLQNRRGLDLLFLKEGGLCAALKEECCFYADHTGLVRDSMAKLRERLSQRQKLFESSQGWFEGWFNRSPWFTTLISTIMGPLIILLLILLFGPCILNRLVQFVKDRISVVQALVLTQQYHQLKPLEYEPQ",
    "output": "The surface protein (SU) attaches the virus to the host cell by binding to its receptor. This interaction triggers the refolding of the transmembrane protein (TM) and is thought to activate its fusogenic potential by unmasking its fusion peptide. Fusion occurs at the host cell plasma membrane (By similarity).; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSETSPHRSGSVAVIGRPNVGKSTLTNALVGAKVSIVSNRPQTTRHRLLGIATFPEGQLMLVDTPGLHREQKRAMNRVMNRAARGSLEGVDAAVLVIEAGRWDEEDTLAFRVLSDADVPVVLVVNKVDRLKDKTALFPFLAQVSEGRTFAAVHPVSALKRKGLEALVSDLLKLVPEAEAMYGEDEITDRSQRFLAGELVREQLMRQLGEELPYATTVEIERFAEDGALLRIGAVIWVEREGQKAIVIGKGGTRLKDIGGKARLQMERLFGAKVFLETWVRVREGWSDDEAALKAFGYD",
    "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDYLVKSIDKTKNLRLLTITAKDVVGEAQKRHDLWSASAAVLGRTLVGSLLLAGAELTDKEELTVRLLGNGPVGPTIVTAMSDLKVKGYVKNPHIALSPKKNGHIDVKKAVGQGMLEVTKDLGLKEPYTGQVPIVSGEIAEDFAYYLTKSEQIPSAVGLSVFVNPNNSIGEAGGFMLQALPGASDALITETIKRIKALPALSTEFLDGMTPEDLARKILGTDCKILEKDDVAFSCDCSKEKYAGILETLKSSQLKAMINEDHGAELTCNFCGNKYHYTENELKDILAKKKEEKDY",
    "output": "Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLTGQHHIPGIESPLMVVLWRVAAGVFLPLVPTMAVFGNVLVILSVYRERNLQTVTNMLIVSLAVSDLFVAIGVMSFGVYYEWNGFKWGLGSFFCHVYQALDVACSTASILNLLAISLDRYIAIGHPISYAQYGARGGRAMISITIVWGVSCAVALPLLLGVNPMENDQCELANPWFNMISSIFSFFIPCIAMIILYTIIFRRLRQRERARSLRQAQRSETDKISSALLGGAQIARQMGKHFKNRTDQILLEISFQTSSFPTISESSDDGSTISPMINSFNNFLPKKSQYPSTLIPAIPECGSMPNLTIIERPAPPEKEKDIELSIMDLHDTVEMLDDKYTSAMITRSFGEELEEILPFIDGSTSVKNSREQLHATRSNTSTTRLLDVKPELRSISVPSIQDEKKMNSRPPENPFAHQNGTNKQRLLPNPGILMKSKSTTLLKTNGYLDTDSLNNNRNSHKKSTADLLPNDDYSFTDSMRVYKNRLFKSLSRATSGWNKPRPSRHMVKKATKQMRREHKATVTLAVVLAVFLFCWLPFFILHLSNSICLVIDSNSDCIGFLPLYLATWLGYLNSSLNPLIYTVFDQRFRNAFRNILSCGFFKKR",
    "output": "Receptor for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. In terms of antagonist responses, would be classed with the D2-like dopamine receptor group. Mediates the effect of dopamine on the inhibition of locomotion. Acts as an antagonist of dop-1 (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTAHIGLSAQHVVDSLGHPDGASRPPVSAESLSRASELLQSNHDTWHIFFREATGHNHMAHSILTALALGASPSELERAYTDTEAIQRPIPAVDPMILTRLDADPQALESLLGWSDLYSTFLTYFQSQIDRHGWQSVVTTYVFSETPLAEKLLIKLYEGMYHSLIHLGLGIEFGQPGIIAEALAQAAAHEDGHIDKLLLGVEAAIAAKDDTRTETTVPKSLVQLVDEVRSHPRIWADLRFGDRWNRMRDSIMDRAADELIPIAAQFRIPASGMMMMAGEHADLLTIRTAEMASTAAYLAGASQSARRPRKIDFFLMHTVTASLFFSVFNAQEWIPRAMRVRLVEWKGRLDLAFYAFCKSPELDACVISDYSDDFTRDMDWAALYAAVNQEHDDGHVAKFMRALRHAERLSRPYEQHPVWAEHFPVKGNMWIKLARMALETTRHSPPDFKWIMGTGFDEAWERPDLKLAENRGQQGQSVP",
    "output": "Baeyer-Villiger monooxygenase; part of the gene cluster that mediates the biosynthesis of the tetrahydroxanthone dimer secalonic acid D . The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase AacuL (Probable). The atrochrysone carboxyl ACP thioesterase AacuM then breaks the thioester bond and releases the atrochrysone carboxylic acid from AacuL (Probable). Atrochrysone carboxylic acid is decarboxylated by the decarboxylase AacuI, and oxidized by the anthrone oxygenase AacuG to yield emodin (Probable). Emodin is then reduced to emodin hydroquinone by a yet unidentified oxidoreductase (Probable). A-ring reduction by the short chain dehydrogenase AacuN, dehydration by the scytalone dehydratase-like protein AacuK and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol . Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) AacuH then yields monodictyphenone . Monodictyphenone is transformed into compounds with the tetrahydroxanthone skeleton via methylesterification by the methyltransferase AacuQ, followed by the action of the flavin-dependent monooxygenase AacuC, the isomerase AacuP, and the short chain dehydrogenase/reductase AacuF or AacuD . AacuF and AacuD should accept the same compound as a substrate but perform the ketoreduction with a different stereoselectivity, thus yielding blennolides B and A, respectively . In the final step of the biosynthesis, the cytochrome P450 monooxygenase AacuE accepts blennolide B and/or blennolide A to conduct the dimerization reaction to furnish the tetrahydroxanthone dimers, secalonic acids D, B, and F ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSGQTTSEYIGHHLQFLKTGDSFWNVHIDTLFFSVLAAIIFLAVFRSVAKKATSGVPGKLQCMVEILVEWINGIVKENFHGPRNVVAPLALTIFCWVFIMNAIDLIPVDFLPQLAGLFGIHYLRAVPTADISATLGMSLCVFALILFYTVKSKGFGGLVKEYTLHPFNHWSLIPVNFVLESVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANAAIAALGIPLHLAWAIFHILIVTLQAFIFMMLTVVYLSIAYNKAEH",
    "output": "Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARVKGGTVTRKRRKKVLKLAKGYYGSKHTLFKSAKEQVMNSYYYAFRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKLAEIDINRKMLADLAVNDAAAFTALAEQAKDALSK",
    "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MILTVKPLQGKECNVQVTENEKVSTVKELVSERLNIPASQQRLLYKGKALADEHRLSDYSIGPEAKLNLVVRPAGERSSGAVGTSSANNDKGGSGVWQLLSTVLAKHFSPADAAKVQEQLIKDYERSLRQLSLDDIERLASRLLHPETEVMDTSYMD",
    "output": "As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Similarly, the bag6/bat3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The bag6/bat3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMSRDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTSVVKHDEERRVNPDDSKED",
    "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MELQVVGANALTVSETTFGREFNEALIHQVVVAYAAGARQGSRAQKTRAEVSGSGKKPWRQKGTGRARSGDIKSPIWRSGGVTFAAKPQDHSQKVNKKMYRGAIKSILSELVRQDRLVVVEKFEIDVPKTKVLVQKLKDMALTDALIITASLDENLFLAARNLYKVDVRDVQAIDPVSLIAFDKVVVTVDAVKQIEEMFA",
    "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKEILITNDDGFEAKGLHELADALRQIPDVNVTIVAPSSEKSACAHSLTLTKPLRFIKIDDNFFKLDDATPSDCVYLALHALYQKKPDLVISGINHGANLGEDITYSGTCGAAMEGVLQGIKSIAFSQFYKNNSIEELGFSLACQIVKFIVPRVLEGEICLPQRQFLNVNIPAVAARDFKGYKVAPAGRRCYATHATLNRNPRGVEYYWLGNAALDYEEGQISDISVINDGFASLTPIQLDMTAHASLENLKKSFQ",
    "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSASRFIKCVTVGDGAVGKTCMLISYTSNTFPTDYVPTVFDNFSANVVVDGSTVNLGLWDTAGQEDYNRLRPLSYRGADVFLLAFSLISKASYENVSKKWIPELRHYAPGVPIILVGTKLDLRDDKQFFVDHPGAVPISTAQGEELRKLIGAAAYIECSSKTQQNIKAVFDAAIKVVLQPPKQKKKKKKAQKGCAIL",
    "output": "Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSDENRELSELIYTRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSADQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDTTSFDEYWKKDSDAELYHFIGKDIVYFHSLFWPAMLEGSHFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLKHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLAAELADPQLYKTFTDAAAVIGEAWESREFGKAIREIMALADVANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPTLSERVEAFLNSELNWDAIEQPLLGHKVNTFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADFPIQETITFDDFAKIDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRQTVMVANLAPRKMRFGVSEGMVMAAGPGGKDIFLLSPDDGAKPGQQVK",
    "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKKQELNQAFTHVFGREADATFFSPGRINLIGEHTDYNGGRVFPAAITLGTYGAARKRDDKLLRFYSANFEELGIIEISLDHLIFNKKDSWTNYPKGVIKYLQEAGHSIDTGMDVYVFGNIPNGSGLSSSSSLELLIGIMAEELFDLKLDRLDLVKIGKRTENDFIGVNSGIMDQFAIGMGAEKKAIYLDTKTLEYDLVPLDLGDNVIVIMNTNKRRELADSKYNERRTECEKAVEELNVLLDIKSLGELDEETFDEYAYLIKDAKRIKRARHAVSENQRTLKAKKALAAGDLEKFGRLVNASHVSLEHDYEVTGIELDTLAHTAWEQEGVLGARMTGAGFGGCGIAIVAKDKVAALKENVGRIYTETVGYAPAFYIAEIAGGSRVLSRK",
    "output": "Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNNYIFIISAPSGAGKSSLLKAFLATDIGKDNYAVAISHTTREPRVGEINSREYYFVTVAEFEQLLSQDGFIEYAKVFKNYYGTSKAELDRLLALGKNIILEIDWQGAQQTRAIYGDRAKSIFILPPSLDELRKRLEKRNTDSKETIDYRMEQVQSEISHADEYDYLLVNDDFSQSLEQLCKYFEQNIQS",
    "output": "Essential for recycling GMP and indirectly, cGMP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRIVVSGGGTGGHIYPALAMIREIERRTPCEVLYIGTENGLEADIVRRAGIPFESIEISGIRRSLSFENVKTGFRFLKSVVRVRKLLRDFQPDIVVGTGGFVCGPVLYTAAKMGYKTLVHEQNSLPGITNKFLARYVDRVALSFKGSGHHFGKNKGKTILIGNPRASEVAMLQIDPVEEKRKYGFEQDRPLIVVYGGSRGAPAINKAVVDMIPKLTETDWSLLFVTGQVHYEDIQAQLGTLPDRIQLRPFIYDLPLILKASQLVISRSGASTLAELTTLGLPSILIPSPYVTENHQEVNASSLVETGASLLIRESELTGDRLFDACTKAIADQADMSKASLALGMPNAASDLVDELLRLIQRKN",
    "output": "Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGSFSMWHWLIVLVIVLLLFGRGKIPELMGDVAKGIKSFKKGMTDEDAPDTAKTVDHKADETK",
    "output": "Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSNEKMDTSPPSYDSHFTLETSMHRQLKDKRIILASGSPRRKQLFEQMGFPNVETCVSGFPEDLNKSMYITPWEYAADTSVQKAIAVYEKLAAEEDSPDIVVSADTILILDSEIMEKPNDPKHHLAMLKKLRNSKTPHKVFTAVSVIVPMEVPIHPGYVMKTHLEETQVKFDPSITDEFLEAYVRCGEGSDKAGGYAIQGHGALLIESIIGDFSNVVGLPIRATFKLMEEALEQGDADNYD",
    "output": "Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKMKSLREVDAEIYSLILQEKKRETNKILMIASENYASRAVMEAQGSLFTNKYAEGYPGRRYYGGCEYADEVERLAQERAKQLFNVEHVNVQPHSGTQANMAVYFAMLQPGDTIMGMSLTHGGHLSHGSPVNFTGKLYKTVFYGVNKETGYIDMDEVRRLAQEHKPKIIITGASAYPRTIDFKAFSEIAKEVGAYLMADIAHIAGLIATSMHPSPVPYSDFITTTTHKTLRGPRGGVVMCKAQYAKAIDKTVFPGIQGGPLVHVIAAKAVAFKEALSEDFKEYQKKVIKNAKTLAEALKKKGFKLVSDGTDNHLMLVDLTNFNITGKEAEEALDKAGITVNKNTIPFDTKPPTVTSGIRIGTPSVTTRGMGEEEMEKIAEIIERVIKNISNDSVIKDMQKKVQELCKKFPIY",
    "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATSKSQQFQLIEGMELQITVTGLPNGSSVRAEFHLKNCTRAWILHWGCIYQGNNHWYIPSEHSSKQGALQTTFVKSGDAYVVILELRDPRVRAIEFVLKDGSHNRWLRQHNGNFRVEIPWNDLHAHHRIPKTLIERRAHKIWDRKGRPQSSAREQQIDYDNAVRELHAELARGISLDELQANSTVPVEKEETSEPHHTMIQSYRRKHDVQKWLQKYTEPINRSGSVKSSALAELSKRSVGQENLVSQKSFHVRNYEITVLQRDVKGDCRLWIATNMAGPTVLHWGVAKSSAGEWLIPPPDVLPEKSKFVHGACQTQFTDMSSREHSYQFIDINLKRGGFVGIQFVIWSGGYWVNNNGANFVVNLKSADSTSGKLDVDEKYVLKWLLDEISEREKEAERSLMHRFNIATELTERCKDEGEGGCIGIMVWMRFMATRHLTWNKNYNVKPREISEALERFTNLMEKIYLQQPNKREIVRLTMALVGRGGQGDVGQRIRDEILVIQRNNHCKSGMMEEWHQKLHNNSSADDVIICEALLNYVRSDFRIDAYWQTLQTNGLTKERLASYDRPIVSEPRFRSDSKEGLIRDLTMYLKTLKAVHSGADLESAIDTFLSPSKGHHVFAVNGLSPKLQDLLNLVKRLVREENTEPLIEKLVDARIQLHPALRAPRTRAKDLLFLDIALESCFKTTIEKRLISLNFNNPPEIIYVICVVLENLCLSIVNNEEIIFCTKDWYRVSEAYRPHDVQWALQTKAVLDRLQLVLADRCQHYFTIIQPTAKYLGQLLRVDKHGIDVFTEEVIRAGPGAVLSTLVNRFDPSLRKIANLGCWQVISSADAYGFVVCVNELIVVQNKFYSKPTVIIASKVTGEEEIPAGVVAVLTPSMIDVLSHVSIRARNSKICFATCFDQNVLSNLKSKEGRAISIHTKSTGLVISDGNNSDVSVRHIFISSVPRGVISKGKKFCGHYVISSKEFTDERVGSKSYNIKFLRERVPSWIKIPTSAALPFGTFENILSDDSNKDVARRISVLKDSLNRGDLTKLKSIQEAILQMSAPMALRNELITKLRSERMPYLGDESGWNRSWVAIKKVWASKWNERAYVSCKKNKLDHDAVCMAVLIQEVICGDYAFVIHTNNPVSGDSSEIYTEIVKGLGETLVGAYPGRAMSFITKKTNLKSPTVISYPSKRIGLYSKPSIIFRSDSNNEDLEGNAGAGLYDSVIMDEAEEVVVDYSREPLIMDKSFRVRLFSAIAEAGNVIESIYGCPQDIEGVVKGGHIYIVQARPQV",
    "output": "Mediates the incorporation of phosphate into alpha-glucan, mostly at the C-6 position of glucose units."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLATTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGTGATCAMFVLGSLREIIGNGTLFDGADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDERMKKRRAEAAAERALPNGETGNV",
    "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MISFLLLIFLIQLAIYIVNTIGSSTIDDLLWILYLRLPMPISKDTRKHGELKHDVVQLKREMNATSSQDEFAKWAKLRRRHDKAMEEYEAMNRSMGSRKTSFQFSIKIARWLTLNGPRLFIQFYYTKTPVFDLPAGWFPYPVEWILSFPRAPLGSVSIQVWSSACATAISLAGDVVIAVVQRRQASNRQAQAVPAGKSEAATK",
    "output": "Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAPSNLPPIFNATSQDIEMLLAAQCHLGSKNLQVHMDPYLWKTRPDGINVINIGKTWEKIVLAARIIAAIDNPADVCVISARPYGQRAVLKFAAHTGAAAIAGRFTPGNFTNYITRSFKEPRLIIVTDPRTDHQAIKEASYVNIPVIALCDTDSPTEFVDVAIPTNNKGRHAIGLIWWMLAREVLRLRGTIASRETEWDVVVDLYFYRDPEAEENKEIEEAKVPGAEEVGAAAIESGLVGDSWEAQVAPAFAATGAAVPAGAAPGWEAEAAGEWAASSGAAAGAAETWATDTAAPDAGVKW",
    "output": "Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTDDVALPLQFTDAAASKVKNLISDENNPDLKLRVYITGGGCSGFQYGFTFDDKVNEGDMTIEKSGVALVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKTTCGCGSSFSI",
    "output": "Required for insertion of 4Fe-4S clusters for at least IspG."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPPTMLASVPTRPRSHPFRRRRGAAAAAPPLLPDQIAAAAAAAAKRPAESSTSASSCFHSEVISATSTTCPTSLAAAQRPEKRPRYQDVDEEQPAASECSEIIGGARPRAAEVEVSESSCLASVLESYLACPEQLANDAETTAYSSAREDLTLSETEEEEEEEEVRSGPCICTDCSFSPLHESSSSSDDDNAVPSPTFSLFLALAEQFVPFTHPKTPTATDVALQAGEGKRFEDLDNEVSYERFRRRERRGVVARDYIEVYSSMLGSYGRAVVEQRVVMVNWIMEHSQAMKLQPETVFMGIGLMDRFLTRGYVKGSRNLQLLGIACTTLATRIEENQPYNCILQKAFKVGINTYSRSEVVAMEWLVQEVLDFQCFVTTTHHFLWFYLKAANADDRVEDLAKYLALLSLLDHKHLSFWPSTVAAAVVALACLATNNESSCHLVMETHMRTKNDDLPECLMSLEWLTNYAS",
    "output": "Meiosis-specific cyclin. Required for normal homolog synapsis and recombination in early to mid-prophase 1."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKYLIGIIGLIVFLGLAWIASSGKKRIKIRPIVVMLILQFILGYILLNTGIGNFLVGGFAKGFGYLLEYAAEGINFVFGGLVNADQTTFFMNVLLPIVFISALIGILQKWKVLPFIIRYIGLALSKVNGMGRLESYNAVASAILGQSEVFISLKKELGLLNQQRLYTLCASAMSTVSMSIVGAYMTMLKPEYVVTALVLNLFGGFIIASIINPYEVAKEEDMLRVEEEEKQSFFEVLGEYILDGFKVAVVVAAMLIGFVAIIALINGIFNAVFGISFQGILGYVFAPFAFLVGIPWNEAVNAGSIMATKMVSNEFVAMTSLTQNGFHFSGRTTAIVSVFLVSFANFSSIGIIAGAVKGLNEKQGNVVARFGLKLLYGATLVSFLSAAIVGLIY",
    "output": "Transport of the pyrimidine nucleoside uridine."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVSSMKVEWYLDFVDLNYEPGRDELIVEYYFEPNGVSPEEAAGRIASESSIGTWTTLWKLPEMAKRSMAKVFYLEKHGEGYIAKIAYPLTLFEEGSLVQLFSAIAGNVFGMKALKNLRLLDFHPPYEYLRHFKGPQFGVKGIREFMGIKDRPLTATVPKPKMGWSVEEYAEIAYELWSGGIDLLKDDENFTSFPFNRFEERVKKLYRVRDRVEAETGETKEYLINITGPVNVMEKRAELVANEGGQYVMIDIVVAGWSALQYMREVTEDLGLAIHAHRAMHAAFTRNPKHGITMFALAKAARMIGVDQIHTGTAVGKMAGDYEEIKKINDFLLSKWEHIRPVFPVASGGLHPGLMPELIRLFGKDLVIQAGGGVMGHPDGPRAGAKALRDAIDAAIEGLDLEEKAKSSPELKKALDKWGYLKPK",
    "output": "Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAIDVFYDDDADLSIIQGRKVAIIGYGSQGHAHAQNLRESGVEVVIGLREGSKSRAKAEEAGFTVKTNAEAAEWADVIMLLAPDTSQAKIFAEDIEPNLNDGDALFFGHGLNIHFKLIEPADNIIIGMVAPKGPGHLVRRQFVDGKGVPCLIAVEQDPKNNGRDLALSYAAAIGGARAGVIPTTFEAETVTDLFGEQAVLCGGTEELIKTGFEVLVEAGYEPEMAYFECLHEMKLIVDLMFEGGIANMNYSVSDTAEFGGYLSGPRVIDADTKKRMKDILTDIQDGTFTKRLVANVEGGNKELEELRASYNDHQIEKTGAKLRDLMSWVKVDARAETA",
    "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MYPAHLLVLLAVCVSLLGASDMPPQPLNLVQFSNMIQCANHGRRPTSNYMDYGCYCGKGGSGTPVDELDRCCKIHDDCYGEAEKSQKCAPYWTWYTWKCGSDGPQCDDSETGSRRFVCGYDATAAKCFAKAPYNKENYNIETRCQ",
    "output": "Snake venom phospholipase A2 (PLA2) that inhibits collagen-induced platelet aggregation. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MADEQNLDAQAQDQAAEAGAGDELTTRVQVLEEQLAAAQDQSLRVAADLQNVRRRAEQDVEKAHKFALEKFAGDLLPIIDSLERGLDLSNPDDESIRPMREGIELTLKMFQDTLKRYQLEAIDPHGQPFSADQHQAMAMQESADVEPNTVLKVFQKGYQLNGRLLRPAMVVVSKAPSPATPSINEQA",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSTPSQRRSGRGGGPSGTPLSPTRITRLQEKEDLQELNDRLAVYIDKVRSLELENAGLRLRITESEEVVSREVSGIKAAYEAELADARKTLDSVAKERARLQLELSKVREEHKELKARNAKKEADLLAAQARLKDLEALLNSKEAALSTALGEKRNLENEVRDLRAQVAKLEGALSEAKKQLQDEMLRRVDAENRLQTLKEELEFQKNIYSEELRETKRRHETRLVEIDNGRQQEFESKLAEALQDLRRQHEDQIRHYRDELEKTYGAKLENAKQSAERNSSMAGAAHEELQQTHIRIDSLSAELSQLQKQLAAKEAKLREVEEALSREREGGRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEINAYRKLLEGEEERLRLSPSPSSQRGARSSGLQHSGAGSAKKRRLEDGEGREGREGRTSFSHHARTSGRVGVEEVDLEGRFVRLRNKSNEDQALGNWQVKRQNGDDPPLTYRFPPKFTLKAGQAVTIWASGAGATHSPPSDVVWKAQSSWGSGDSLRTALINSNGEEVAMRKLVRTVIINDDDEDEEDDEVSIHHRHHHSGCSGSADPAEYNLRSRTVLCGTCGQPADKGSAAAASSASSASTVTVSRGYRSSGGGIGEGLLGRSYVLGGAGPRRQAPAPQGCSIM",
    "output": "Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADASNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKMDGRQMFMQLAPISDKK",
    "output": "IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKIALFGGSFDPPHNGHNSVVLEALEKLDIDKLIIMPTYINPFKQSFSADEKQRFLWVKKLWGHLPKVEICDFEIRQKRPVPSIESVKYLYKLYNPSKFYLLIGADHLEKLHLWHDFEKLNSLVEFVIANRNDIGIPKNFKDLKTNKKIASSFIRDTLNTNEVCEEIKDEVKKYYEKLQKN",
    "output": "Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTEPLILQPAKPADACVIWLHGLGADRYDFMPVAEALQESLLTTRFVLPQAPTRPVTINGGYEMPSWYDIKAMSPARSISLEELEVSAKMVTDLIEAQKRTGIDASRIFLAGFSQGGAVVFHTAFINWQGPLGGVIALSTYAPTFGDELELSASQQRIPALCLHGQYDDVVQNAMGRSAFEHLKSRGVTVTWQEYPMGHEVLPQEIHDIGAWLAARLG",
    "output": "Hydrolyzes carboxylic ester bonds with relatively broad substrate specificity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSCLPALDKFLQNYHQSYLSTLGELPRYYPRGESSLCIQGEFVEASTEAVGWLPVKREQPGSFTNVEHALELKLWPDIHSFYGQYFAAPVLFDSTWGTGELLQVWNEADFDALQQNIIGHLMMKQKLKQPPTWFIGLLDEGDKMLTVDNADGSVWIEIPGELPSVQLATSLAEFIAALSPRIAPPVKHEELPMPAQDHPGIFASFKRMWHNLTGKR",
    "output": "Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MYGIEYTTILTILISIILLNYILKTITNTMDYIIFRFLLLIALISPFVRTQNYGMYLPITGSLDAVYTNSTSGEPFLTSTLCLYYPAEAKNEISDDEWENTLSQLFLTKGWPIGSVYFKDYNDINTFSVNPQLYCDYNVVLMRYDNTSELDASELADLILNEWLCNPMDISLYYYQQSSESNKWISMGTDCTVKVCPLNTQTLGIGCKTTDVNTFEIVASSEKLVITDVVNGVNHNINISINTCTIRNCNKLGPRENVAIIQVGGPNALDITADPTTVPQVQRIMRINWKKWWQVFYTVVDYINQVIQVMSKRSRSLDAAAFYYRI",
    "output": "Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion. This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSAQPVDIQIFGRSLRVNCPPEQQDALNMAAVDLNERLQDLKVRTRVTNTEQLVFIAALNVCHELAQERLKTRDYASNMEQRIRMLQQTIEQALLEQGRISERQDAQFE",
    "output": "Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKTLIIAEAGVNHNGDLNLAKKLIEIAADSGADFVKFQSFKAKNCISTKAKKAPYQLKTTANDESQLQMVQKLELDLKAHKELILHAKKCNIAFLSTPFDLESVDLLNELGLKIFKIPSGEITNLPYLKKIAKLNKKIILSTGMANLGEIEEALNVLCKNGAKRQNITLLHCTTEYPAPFNEVNLKAMQSLKDAFKLDVGYSDHTRGIHISLAAVALGACVIEKHFTLDKNMSGPDHKASLEPQELKMLCTQIRQIQKAMGDGIKKASKSEQKNINIVRKSLVAKKDIKKGEIFSEGNLTTKRPANGISAMRYEEFLGKIATKNYKEDELIRE",
    "output": "Involved in biosynthesis of legionaminic acid (5,7-diamino-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into flagellin via O-linkage to Ser/Thr. Catalyzes the condensation of 2,4-diacetamido-2,4,6-trideoxymannose with phosphoenolpyruvate (PEP) to give N,N'-diacetyllegionaminic acid."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MILVFDVGNTNIVLGVYRGKELIENWRIATDKDKSSDEYAMVIHQFFHYNGLNIHDVDDVIISSVVPNIMYSLENASRKLFKREPLIVGSGIKTGMNIKYDDPKQVGADRIVNAIAAYEKYGGPLIIVDFGTATTFCAVSEDGEYLGGAISPGIKISSEALFEKAAKLPRVELINPKKVICKNTVSSMQAGIVYGYIGLVENIVRNMKKELKSSSCKVIATGGLSTLIAGGTDSIDVVDKFLSLDGLNIIYERNRKDRILSNKKS",
    "output": "Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNKNVVIKSLAALTILTSVTGIGTTLVEEVQQTAKAENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK",
    "output": "Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEPCLLMWGILTFITVSGYTTDLCDDDPPNLKHATFKALTYKTGTVLNCDCERGFRRISSYMHCTGNSSHASWENKCRCKSVSPENRKGKVTTKPEEQKGENPTEMQSQTPPMDEVDLVGHCREPPPWEHENSKRIYHFVVGQTLHYQCMQGFTALHRGPAKSICKTIFGKTRWTQPPLKCISESQFPDDEELQASTDAPAGRDTSSPFITTSTPDFHKHTEVATTMESFIFTTEYQIAVASCVLLLISIVLLSGLTWQRRRRKSRTI",
    "output": "Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSRVAKAPVVLLAGVEVKLNGQEITVKGPKGELALVAHNAVVLTQEENTITFGPREGFDKAWAQAGTVRALVNNMVVGVTEGFTKKLTLKGVGYRANVAGNTVNLTLGFSHPVAHELPTGVKAECPSQTEIVLTGTDKQVIGQVAADIRAYRSPEPYKGKGVRYADEVVRTKEAKKK",
    "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSPQTETKASVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEEDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAAFARELGVPIVMHDYLTGGFTANTSLSMYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHVHSGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGVFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIKAACKWSPELAAACEVWKAIKFEFEPVDTVDKV",
    "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSDTNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSWILERGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVDPEFVRKEIAEGRAILPANINHPEAELMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAKEFKETGSHLYQ",
    "output": "Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTNLRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGVCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFLKTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLPFLHETGSNNPSGLSSDADKIPFHPYYTIKDILGVLLLILALTSLVLFSPDLLGDPDKYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAEVPFLHTSKQRSMMFRPFSQCLFWILVADLLTLTWMGGQPVEHPFIIMGQLASILYFLLILVMMPITSLFENNLLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKIAIFDSGIGGLSLLNEALKRFRGVEFIYFADNKNAPYGTKSKDEIIRLCLNCVQFLTNLSVDMIVIACNTATSAAITELRSSFSVPIIGMEPAVKLGVNAGGDILVVATPATISGNKLSDLIHKVNLESKTHLLALPKLVEFAQNMEFDSLEVLKYLKDEISKFDLSNISLLVLGCTHFNYFKDSFRAILPNKTGIIDGVNGTINQMIRRLGGVSEFGDKNSIRYISSTENLNVKKIEPYLKRLDIMREIN",
    "output": "Provides the (R)-glutamate required for cell wall biosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKKAIIGRKVGMTQIFDEKGKVIPVTVVEAGPCVVVQKKTLENDGYEAIQVGFDEIREKLANKPRKGHFAKAGATLRRTLKEFRLDDISQYEVGNEIKADVFGAGDKVDVSAVSKGKGFQGSIKRWNQQRGPMTHGSKFHRAPGSMGASSDPSRTFKNKRMPGHMGSVNTTVLNLEVVKVIAEKNLILIKGGIPGPNKGTVVIKDTVRA",
    "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSENIGKIVQVIGAVVDVSFPNGKLPPILTALEIHNPNSIDAPKLICEVAQHLGDDIVRTIAMDATEGLKRGMDVLDTGHPIMAPVGKASLGRIMNVVGQPIDGLGVIDTKTYLPIHRKPPSFLDQNTSVEPLETGIKVIDLLVPFPKGGKMGLFGGAGVGKTVILMEMINNIARQHGGISVFAGVGERTREGNDLYHEMKEAGVLEKAILVYGQMNEPPGARSRVALTALTCAEYFRDEEHQDVLLFIDNIFRFIQAGSEVSALLGRMPSAVGYQPTLGTDLGSLEERITSTHNGSITSVQAVYVPADDLTDPAPATTFSHLDGTLVLSRQIAELGIYPAVDPLDSTSRILEPNFVGEEHYTVARGVQKILQKYKELQDIIAILGMDELSDEDKLVVSRARRIQRFLSQPFHVAETFTGTAGEYVKLEDTIKGFKGILAGEYDHLSESDFYMVGNIDSAVAKYEKRKESK",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTHQAAEVAKRRTFAIISHPDAGKTTITEKLLLMGKAIAVAGTVKSRKSDRHATSDWMEMEKQRGISITTSVMQFPYRDHMVNLLDTPGHEDFSEDTYRTLTAVDSALMVLDGGKGVEPRTIALMDVCRLRDTPIVSFINKLDRDIRDPIELLDEIEAVLKIKAAPITWPIGCYRDFKGVYHLADDYIIVYTAGHGHERTDVKIIEKLDSDEARAHLGDEYDRFVDQLELVQGACHAFNQQEFLDGQLTPVFFGTALGNFGVDHVLDAVVDWAPRPLPRVANERTVEPVEEKFSGFVFKIQANMDPKHRDRIAFMRICSGKYDKGMKMRHVRTGKDVRIGDALTFFSSEREQLEEAFAGDIIGLHNHGTIQIGDTFTEGESLSFTGIPHFAPELFRRVRLRDPLKSKQLRQGLQQLAEEGATQVFFPERSNDIILGAVGVLQFDVVASRLKEEYKVECSYEPITVYSARWIDCSDKKKLEEFSNKAVENLAVDGGGHLTYLAPTRVNLALMEERWPDVKFRATREHH",
    "output": "Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSLMVISMACVAFFLLQGAWPHEGFRRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGTFNHTLRLIGEHIDGVSKGNFSIGRMTQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNRTFQADFPLDPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNSSNSWPSPTEPSSETGNPRHLHVLIGTSVVKLPFTILLFFLLHRWCSNKKNASVMDQGPAGNRTVNREDSDEQDHQEVSYA",
    "output": "Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity . Able to activate NK cells citotoxicity and cytokine production such as IFNG . Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 reprensented in this entry ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIQHMTRLKVADNTGAKEVGVIKVLGGSKKRYASVGDIVVVSVKKATPAGLIAKGQMAKAVIVRTKKSIRRESGLLIRFDENACVLIKEDKTPRGSRIFGPVAREIRDRGYTKIASLAPEVL",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVMGFSDLMANFARIQQANILIRGLRAVADFEYEMQLAHMNRHLMPQLESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMDKLK",
    "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKLPEALGSIHFVGIGGIGMSGIAEVLNNLGYTVQGSDVAENANVKRLRENGIAVTVGHKAENIDGAEVVVVSSAIKRDNPELLAARAKRLPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSLVATLLDKGGFDPTVINGGIINAYGTNARLGAGDWMVVEADESDGTFLKLPAEVAIITNIDPEHLDHFKTFDKVQEAFRTFVENVPFYGFAVMCIDHPVVQALVGRIEDRRIITYGENPQADVRLVDVDLRGGITRFGVVFRDRAGTAEHRIDGLKLPMPGKHNALNATAAIAVARELRVPDDRIIEAIGGFGGVKRRFTRTGEWKGATIFDDYGHHPVEISAVLRAARAATEGQVIAVVQPHRYTRLASLFDEFCTCFNDADHVIVAPVYAAGESPVPGADSEHLVQGLRARGHRSVTALKGPEELAGLVAGLAKPGDFVICLGAGTITQWAYALPGELEKLG",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLKQRTIKQIVKTVGIGLHSGRKVELTLRPAAPDTGIVFSRVDLATPVDIPASAMAIGDTRMASVLQKDGARVSTIEHLMSACAGLGIDNLYIDVTAEEIPIMDGSAGSFVFLIQSAGIEEQNAAKKFIKVTKPVEIRDGDKFARLDPYFGFKLKFTIDFRHPAVDKTGQALEVDFANTSYVREIARARTFGFAHEVEMMRELGLARGGSMDNAIVLDEYRILNNDGLRYDDEFVKHKMLDAIGDLYVIGHPLLAAYDAYKSGHGLNNALLRELLAHEDSYEIVTFDDTQKAPRGFAYETQTAFA",
    "output": "Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE",
    "output": "Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQAKVHVKKGDTVLVASGKYKGRVGKVKAVLPRKMAVIVEGVNLVKKAVRPSPKHPQGGFVEQEAPLHASKVRPICPACGKPTRVRKKFLEDGRKIRACAKCGGSLDVEE",
    "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTKSYNYKLTHFVTSAPDIRHLPVDSGIEIAFAGRSNAGKSSALNTLTNQKSLARTSKTPGRTRLINLFEVESGIRLVDLPGYGYAEVPEELKRKWQRALGEYLQMRDSLKGLVVLMDIRHPMKDLDQQMVQWAVDVNIPVLVLLTKADKLASGSRKEQLNQVREAALAFMGDVQVETFSSLKKQGVDKLRQKLDDWFAAIPPAQGSPETE",
    "output": "Necessary for normal cell division and for the maintenance of normal septation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGRFSNADGPGDDADEREVTPALTVGEGDIDASLRPRSLGEFIGQPRVREQLQLVLEGAKNRGGTPDHILLSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLIEGDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTAHMDFYEPAELERVLARSAGILGIELGAEAGAEIARRSRGTPRIANRLLRRVRDYAEVRADGVITRDIAKYALEVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEATTVEEVCEPFLVRAGMIARTPRGRVATAQAWKHLGMTPPAGAGGLGQVGLFE",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSDRPIVLAAIIGAHGLQGEVRLKLFTEDMGAYRTLDGAGRSFTLKTIRPGPNGAVARFAEIGDRNAAEALRGTELSVPRSALPPLAPGEYYHVDLIGLPCLVDGAPVGVAAMVEDFGAGDVLEIEKPDGKRFMVPVAKAVTIEPDRLLIDPEFVE",
    "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKTANHPDTVLIVDFGSQFTQLIARRIREAGVFSEIVPFQSAEAAFKRINPKAVILSGGPASTSDIGSPRAPQIVFDAGVPVLGICYGQMAMCVQMGGVAESSNHREFGRAFVEIEKDSPLFEGLWATGQRHQVWMSHGDRVIALPPGFQVFGKSESSPFAIFGNVERKMYGIMFHPEVVHTPDGARLLRNFVHNIAGIEGDWTMRAYREHAVEAIRKQVGKGKVICALSGGVDSSVAALLIHEAVGDQLTCILVDHGLMRKDEAAGVVAMFRQHYNLPLILVDASEKFISALEGEVDPEKKRKTIGRLFIEVFEEEAKKLGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMQLVEPLRELFKDEVRALGKELGLPESFIGRHPFPGPGLAIRCPGGITREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYHYDMAFLGAAATRIINEVRGINRVVYDVTSKPPGTIEWE",
    "output": "Catalyzes the synthesis of GMP from XMP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQLIDGKSLAHKVQENVAKEVEELKQVKNIVPGLAVLLIGDDPASHAYVNMKAKACERVGFYSITHNMPDTISQDEIIATIEMMNANPRIDGILVQLPLPKHIDTNKILEVIDPKKDVDGFHAYNVGRLVTGLDSFVACTPLGVMKMFEEYEIDLEGKDVCVVGASNIVGKPMASLLLNANATVTITHIFTKDLKAHTSQADIVVVGVGVPGLIKEDMVKEGAIVIDIGINRIEDGSLVGDVDFKNVAPKCSYITPVPGGVGPMTIAMLLSNTLKSAKQRA",
    "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEEKYLPELMAEKDSLDPSFTHALRLVNREIEKFQKGEAKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEDIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRTRGVTTPAITRGRGGVTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYSTAYDDQSYDSYDNSYSTPAQSGADYYDYGHGLGEEAYDSYGQEDWTNSRHKAPSARTAKGVYREQPYGRY",
    "output": "RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion . Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6 (By similarity). Involved in splice site selection of vascular endothelial growth factor. In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer . Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members. Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity. May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing. Can bind FABP9 mRNA (By similarity). May play a role as a negative regulator of cell growth. Inhibits cell proliferation (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MILEHVLVLSSFLFSIGIYGLITSRNMIRALMSLELMLNGVNLNFVTFSDFFDSRQLKGDIFSIFVIAIAAAEAAIGPAILSSIYRNKKSIRINQSNLLNK",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGITVLKNEGLDFHARISTPLSEIDDDIQKELLDLTKKVKIAGFRAGKVPVSIVKKKYGTSVRNDIIERRINHSVNHVIKEHNLNIIGRPKIEELQNESDKALEFTVKIELLPKITIPDLKKISLDRPKLEVNSKDVEEQLEKLAALTKNYTKESKAKIKDGDQVTIDAIGYIKEKAFEDGKLNDFKVIIGSNALIPGFEKQLIGSKTGSEVDVNVTFPENYHAKDLAGKDARFVVQIKAVHTAEPTVIDDEFAKKFQSNSLEELRTHFTKQIENESEEAINTIMKMNLFDKLEKLLDFDVPESLLEQEKNILKSGTDKNEQDESLLKDKSSKEITAYYNKLALRRVRIGLLLAEYAKSKNLQLEPDDLRKVIMQQARNFPGQENMIFDFYKNNPRAIEGLKGPALEDKAVQYIFNHEIKLKEKKYTKEELEKYLEAEEQRITLV",
    "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGLARATAGLGPCCPPAPALLGAGLRWGGFLFAWILVSFSCHLASTQGAPEDVDVLQRLGLSWTKAGGGRSPAPPGVIPFPSGFIFTQRAKLQAPTTNVLPTTLGRELALVLSLCSHRVNHAFLFAIRSRKHRLQLGLQFLPGRTLVHLGPRQSVAFDLDVHDGRWHHLALELRGRTVTLVTACGQHRVPVPLPSRRDSMLDPQGSFLLGKMNPRAVQFEGALCQFSIHPVAQVAHNYCAHLRERCRQVDTYGPQVGALFPWDSGPAFALHPEPALLGLGNLTRNPATLGSRPISRGLMVTMAPAVPTKPLRMVHQDVSKLGSSQTPLVPAKQSARKTPSPFPSAALANSTRVFHSAPAQPRQITATSPTKRPPTKPSVSSLSVTPMKSPQAIQKAGTPSFSRPIPTTQKPTPLTSHPSPSKVSSATVRPVQKTFMTPQPPTLSPQALHPITGLPKKFTIPTVAKPQSKMTSWASKPVLARTNVPKALEQTVVAQSSVSYLGSQTLATALPPLGVGNSRMMPSTRDSTSTPAGSKKITGLEASKKTRHKSSPRKPIPLSSGKTARDASPRDLTTKPSQLSTPALVLAPAHLLSSSPQPTSSSFSFFHLPEPTPFLMLMGPPGSKGDCGLPGPPGLPGLPGSPGPRGPRGPPGPFGNPGLPGPPGAKGQKGDPGLSPGQAHDGAKGNMGLPGLAGNPGPMGRKGHKGHPGAAGHPGEQGQPGPEGSPGAKGYPGRQGFPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGIPGKRGEMGRPGFPGDFGERGPPGLDGNPGEIGLPGPPGVLGLLGDMGALGPVGYPGPKGMKGLMGGVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSHGLPGFPGARGKPGPMGKAGDKGSLGLPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPPGQLGPEGDEGPMGPPGVPGLEGQPGRKGFPGRPGLDGSKGEPGDPGRPGPVGEQGLMGFVGLVGEPGIVGEKGDRGVMGPPGAPGPKGSMGHPGTPGGVGDPGEPGPWGPPGSRGLPGMRGAKGHRGPRGPDGPAGEQGSKGLKGRVGPRGRPGQPGQQGAAGERGHSGAKGFLGIPGPSGPPGAKGLPGEPGSQGPQGPVGPPGEMGPKGPPGAVGEPGLPGDSGMKGDLGPLGPPGEQGLIGQRGEPGLEGDLGPVGPDGLKGDRGDPGPDGEHGEKGQEGLKGEEGLPGPPGITGVRGREGKPGSQGEKGQRGAKGAKGYQGQLGEMGIPGDPGPPGTPGPKGSRGTLGPMGAPGRMGAQGEPGLAGYNGHKGITGPLGPPGPKGEKGEQGEDGKTEGAPGPPGERGPVGDRGDRGEPGDPGYPGQEGVQGLRGEPGQQGQPGHPGPRGRPGPKGSKGEEGPKGKPGKAGASGRRGTQGLQGLPGPRGVVGRQGPEGMAGQDGNPGRDGRPGYQGEQGNDGDPGPVGPAGRRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGGTGLPGNQGEPGSKGQPGDSGEMGFPGVAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIIGPPGMLGPSGLPGPKGDRGSRGDWGLQGPRGPPGPRGRPGPPGPPWHPVQFQQDDLEAAFQTWMDAHGAVRLEQGYSYPDQLMLDQGGEIFKTLHYLSNLIQSIKTPLGTKENPARVCRDLMDCEQKMADGIYWVDPNLGCSSDTIEVSCNFTHGGQTCLKPITASKAEFAVSRVQMNFLHLLSSEGTQHITIHCLNMTVWQEGPARPSARQAVRFRAWNGQVFEAGGQFRPEVSMDGCKVHDGRWHQTLFTFRTQDPQQLPIVSVDNLPPVSSGKQYRLEVGPACFL",
    "output": "Plays a role during the calcification of cartilage and the transition of cartilage to bone."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGKGSMTAHATPNEPDYPPPPGGPPPPADIGRLLLRCHDRPGIIAAVSTFLARAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAVDELQRDFGSTVADKFGIDYRFAEAAKPKRVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIANHPDLAAHVRPFGVPFIHIPATRDTRTEAEQRQLQLLSGNVDLVVLARYMQILSPGFLEAIGCPLINIHHSFLPAFTGAAPYQRARERGVKLIGATAHYVTEVLDEGPIIEQDVVRVDHTHTVDDLVRVGADVERAVLSRAVLWHCQDRVIVHHNQTIVF",
    "output": "Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEQKQMQENSYDESQIQVLEGLEAVRKRPGMYIGSTSGKGLHHLVWEIVDNSIDEALAGYCDEINVSIEEDNSIRVTDNGRGIPVGIQEKMGRPAVEVIMTVLHAGGKFGGGGYKVSGGLHGVGASVVNALSTELEVFVHREGKIHYQKYERGIPVADLKVIGDTDQTGTITRFKPDPEIFQETTVYEFDTLATRMRELAFLNRNIKLTIEDKREHKQKKEFHYEGGIKSYVEHLNRSKQPIHEEPVYVEGSKDGIQVEVSLQYNEGYTNNIYSFTNNIHTYEGGTHEVGFKTALTRVINDYGRKNSILKDADSNLTGEDVREGLTAIVSIKHPNPQFEGQTKTKLGNSEARTITESVFSEAFEKFLLENPNVARKIVEKGTMAARARVAAKKARELTRRKSALEVSSLPGKLADCSSKDPAISEIYIVEGDSAGGSAKQGRDRHFQAILPLKGKIINVEKARLDKILSNDEVRTIITAIGTNIGGDFDIEKARYHKVIIMTDADVDGAHIRTLLLTFFYRYMRQIIEHGYIYIAQPPLFKVQQGKKIQYAYNEKELEKILAELPAQPKPGIQRYKGLGEMNPTQLWETTMDPEVRSLLQVSLQDAIEADETFEILMGDKVEPRRNFIQENAKYVKNLDI",
    "output": "A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKYNAGTFDVIVVGAGHAGCEAALAAARMGAKTLMLTMTLDSIAMMPCNPSIGGTGKGHLVREIDAIGGEMGINTDKTFIQSRMLNTGKGPAVHSLRAQADKNKYHTEMKKTIENEPNLLLKQAEVVDLIIEDNTVKGVVTRSGASFYSHSVILATGVYLRGKIYIGEVNYESGPNGLFPSMHLSEKLTKLGCNMRRFKTGTPARIHQDSVDFSKMEEHLGDEEIVPFSFMNDGIEKKQVPCWLTRTTGETHRVIMENLNRSAMYRGDMESVGPRYCPSIEDKVVRFSDKPSHQIFIEPEGLDTKEMYVQGMSTSLPEEVQDAMLKTVIGLESAVIMRPAYAIEYDCIDPTQLKPTLEVKHIENLFSGGQFNGTSGYEEAAAQGLMAGINAVLKTKGEEPFVLDRSEAYIGVLIDDLVTKGTNEPYRMMTSRAEYRLILRQDNADMRLTEKSYKIGLASKERLERYLLKKSHIEEEITRLKKTNVSPEKANPILEENKSSLIKAGMSLYDLLKRPEVTYKVLKKIDENRNVDIVRDAQEQCEIIIKYEGYIEKQLRQIDQFKKLENKILPQEIDYHGIDGLRLEARQKLSDIQPMSVGQASRISGVSPSDISVLMIYLEQRRRQKNGGGT",
    "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLNDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE",
    "output": "Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEPLSLTVYDRNIWHLFKKEEGAPQAMFPTNIKYIFEDDDDVADVDDLVFQQQQPDSELENVIIVEIDGAGQLENVELISDQYEMLSYRRERPVSLASQRSLSWLTSGNDTGGDAGKKSGDISDPAAGPDVPREAPLSIELELVSEFKDYRNLNLEDLKLDELTRIFCIQNKQLQMISDALN",
    "output": "Plays a role in starvation-induced autophagy. Involved in mitophagy. Functions with ATG17 and ATG29 at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions. May be involved in microtubule function, such as chromosome segregation and karyogamy (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRVINLGRQDYLNIWDKMKTFTNTRDKNTKDELWIVEHNPVFTQGVSSKPEHILSNTDIPIVQTDRGGQVTYHGPGQVIIYCLFDLKRLGMGVKRIIEIIENSIIDLLRTYTIKAHLKSGAPGVYIDNAKIAALGLRIKQSRIYHGLSLNIDMDLSPFIQINPCGYQNLKVTQLCDLTDSRDTLNIIAKKLSQILINYVSRNRH",
    "output": "Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGIATFAVVDLETTGNQLDYDEIIQIGITFVRQNQVIDTYHSMIRTDLEIPPFIQALTSIEEEMLVQAPYFNEVADDIYQLIKDCVFVAHNISFDLNFIKKAFEKCNIQFKPKRVMDTLELFKIAFPTDKSYQLSALAESHHIPLNNAHRADEDATTTAKLMIKAFEKFEQLHLDTQKQLYYLSKNLKYDLYHILFEMVRNYQTKPPNNQFEQFEQIIYRKQIDLKKPAVNFDGTLKDLYKNVTQSLNLTYRPQQLYLAEIILDQLMHSDKAMIEAPLGSGKSLAYLLAATMYNIETGRHVMISTNTKLLQSQLLEKDIPLLNDVLDFKINASLIKSKNDYISLGLISQILKDDTNNYEVSILKMQLLIWITETNTGDIQELNLKGGQKMYVDQKIETYVPVRHDIHYYNYIKRNAQNIQIGITNHAHLIHSDSENTIYQLFDDCIIDEAHRLPDYALNQVTNDLNYSDVKYQLGLIGKNENEKLLKAVDKLEQQRILEKLDIAPIDVFGLKININELHDLNEQLFTTIYNIIQTSDVYDDDIHKYHYVYDFETGEILKDLRAIIDKLNKTIEIFNGMNHKTIKSVRKQLLYLHDKFKLIEQSIKDHHTSFISIKNLAQKSTIRLLVKDYDVKDILTKQVLEKFKSLTFISGTLTFNHSFKAFQNWFNEDIDFNTFEISTPLTSSNHTNVFVPNDVETYNYKNLDDYVASIVDYIVEYITVTQSKCLVLFTSYKMMHMVQDLLNELPELEDYVILTQQQNQNYKIVQQFNNFDKSILLGTSTFFEGFDFQANGLKCVMIAKLPFMNKHNIKYWLMDSEFTSTFKDYVLPDAVTRFRQGLGRLIRHEDDKGLIVSFDDRLVNSTYKSFFAQSLEHFKQRKGNIKQFNKLLNQIQRSIDNESKS",
    "output": "3'-5' exonuclease."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKEFIIKANKAVTNGEINLKDLPGSSGRLDLLCRCVNSAFFLSHDMRRDTIFYSVNYGSPNPPVALKFVGSELKRVSPDERSIALFIKKALEKDASDLWKESTSGIYSSKREFRDIISEKKSEGKRIFYLHLNGKPLEDFEFKDDEDFLFVLGDHIGIGDEDEEFLEELGAEKISLSPLELHADHCIILVHNILDRLK",
    "output": "Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNNAFKDALKAGRPQIGLWLGLCSSYSAELLAGAGFDWLLIDGEHAPNNVPTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGAQTLLVPMVQNAEEARLAVRATRYPPAGIRGVGSALARASRWNRVPDYIHQANDAMCVLVQIETREALKNLPQILDVDGVDGVFIGPADLSADMGHGGNPQHPEVQAAIEDAIQQIRQAGKAPGILMANEQLAKRYLELGALFVAVGVDTTLLARGAEALAARFTHNATTTTDNNKSVY",
    "output": "Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPTINQLIAQPRKAQKARNKVPALNACPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVIGYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHILRGVLDTQGVKNRKQRRSKYGAKRPK",
    "output": "With S4 and S5 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "IGMVVECKDGYLMGPDGCKRGCLTRPARYCPNECSRLKGKDGYCYLWLACYCYNMPESAPVWERATNRCGKGK",
    "output": "Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPDIAPSSQPEGDLRYRRVILKLSGESLAESGKRGISDNELLAIAKQIKSAHESGCQIAIVNGGGNILRGASFSGANASVQEATAHYMGMLATVINSLALQDALDSIGLQTRVMSALPVDRVAEQFIRRRAIRHLEKGRVIILSGGIGSPFVTTDTAAAQRALEIEADVILKATRVDGVYSDDPEKNPHAVLYEQLSYNEVIQKKLRVMDATAIALCNEHRKPILVFNFKQDGNIVRAVRGESVGTWIGDPQDTQTNQR",
    "output": "Catalyzes the reversible phosphorylation of UMP to UDP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEAVTGILNTTIAVVFTWVGYKTARIIWKYTPYSYPNARIKAMEAKLLTEQKFNELAESRTLQNFVVNLEDTDYKDYLADVSSYTVEEVEKALERALAGTYELMFKILPKRSKGFFELLLEGWDVRNIANVVKAKLANEPASDYVVELGTMLPKVKAMAEAKTLEEILVILEGTPYEEVYQKLLLGEIDVTRFETELYRMHYGKLLSYALSRKDDERIILEEFVRLSIDRVNILTALRAKKAGLSAEEIKPMLIPGGTVKLDPLLHVDSFDMALAELDSTKYGQVIRDVREEIEKDLSVLEKALNDHIIERISELERFYPLSIATPLSYVLRREREIRKLRAIAKLIENGVEPERIKELAGEVA",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MELWFTEKQTKHFGITARINRTLHTEQTEFQKLDMVETEEFGNMLILDGMVMTTEKDEFVYHEMVAHVPLFTHPNPENVLVVGGGDGGVIREVLKHPSVKKATLVEIDGKVIEYSKQYLPSIAGALDNERVEVKVGDGFLHIAESENEYDVIMVDSTEPVGPAVNLFTKGFYAGISKALKEDGIFVAQTDNPWFTPELITTVFKDVKEIFPITRLYTANIPTYPSGLWTFTIGSKKHDPLEVSEERFHEIETKYYTKELHNAAFALPKFVGDLIK",
    "output": "Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSTPVSAEQQAREQDLVERVLRSFDATADPRLKQVMQALTRHLHAFLREVRLTEAEWETGIGFLTDAGHVTNERRQEFILLSDVLGASMQTIAMNNEAHGDATEATVFGPFFVEGSPRIESGGDIAGGAAGEPCWVEGTVTDTDGNPVPDARIEVWEADDDGFYDVQYDDDRTAARAHLLSGPDGGYAFWAITPTPYPIPHDGPVGRMLAATGRSPMRASHLHFMVTAPGRRTLVTHIFVEGDELLDRDSVFGVKDSLVKSFERQPAGAPTPGGREIDGPWSRVRFDIVLAPA",
    "output": "Catalyzes the ortho-cleavage of the aromatic ring of hydroxyquinol."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ",
    "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSSAIELKKQVVAEIADKFRASKATVIVDYRGLNVAEMTELRKQLREAGIEFKVYKNTMTRRALAEIGLEGLDEVFTGPNAIAFSNEDVVAPAKILSEFAKTHEALEIKGGVIEGSVASKEEIDALAKLPSREGLLSMLLSVLQAPIRNFALAVKAVADKQEEQGA",
    "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDARQLKVEAARAALAHVSDGMRLGIGTGTTAEEFVRLLADKVATGMTVIGVPTSERTAALCRELGVPLSTLEETPELDLTVDGADEVDPELTLIKGGGGALLREKIVAAASQRMIVIADRSKMVETLGRFPLPIEVNQFGLRATEIAIAKTAADLGLSGPITLRMTGGQAFVTDGGHFILDASFGRIPDTRALSNALHAIPGVVEHGLFIGLASTAIIAGGDGIQTVHAARKPGSSTNHDVA",
    "output": "Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLLSDRDLAAEIKAGTLALEPFDPALVQPSSIDVRLDKLFRVFNNHLYTHIDPSRQQDDLTSAVEVPDGEPFVLHPGEFVLASTLEVISLGDQLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHVTLELSNVANLPIMLWPGMKIGQLCIFRLCSPAEHPYGSAVYGSRYQGQRGPTPSRSWQSWRTWPTR",
    "output": "Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSNTLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFEQDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQVK",
    "output": "Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDSWLEYDDIINQDIDIPSNDLSGSGTLCVGVHSSLLENSLNSIDSFISSKEEISWCGNQSTPIATKSHLSCINPQYVNPFDTSPVSVDTEFQDTYLLDAPSFAQPHFSERQSVDKTRSRCLSRNRRRKRHPNLHKNHQRLLGMSFPQDGFRRMPAESVNFSYFRDTGFNEPTIFPSSDTQNTRQLNLSKIATLIGYDCPLALVDVVTQKQIPNKMDMESWVKYMSLEPSKRGRIYDVLSLEVSTTKLAYYVRKPNIVRDLDLVNTVWPPGSFALGEYPHVDTYCLMSAENSYTEFHIEFGGSSAYYNILDGCKIFYLIPGTSKNWEAYTAWLTSSNDSDKKFLPNMVDVCYCVEVHSQQTILVPSGWIYAVVTPCDTISIAGNFLTFLHIYPQLSIYNLELQLGIEKEYQYPYFESIMWYTAIHFYLAFPDNSSRDGIDDIIAEYETGRLFDINAFTEQELDGFEELLNYLYIRAQILRDCDIIIDIYNEPVKISKNNGYNSAYTMVPPDLDEICVDFVQKFGAWITYHHRRSAKHPSCNCFSHLQTKLIDSGPKPANNSYQHQSNFIGVVISTNHNIIKKCQESQIQTGKNNCSFQLVKKRIKSTKKAPSWRSIIKAFKKRENTRCNFLSSLHATTFREDIVVRPKIKSFVLEQLIFQALFSFAINWTPSFFLNHSNFENIALSKETFNFGGEANCENTDTTLFTTWGDQGFRPSDSICYNDFNLLETANSDAEASIHELELQPLNAVNEREVDISQTDMTPSTALDTRVDTRVDSLPEFSNLILSPSSNDDSFQLDDLLSPSSSNLKQQIQKVVPQNSLEFSVGEKEKKAAEYSLLHTFSYKRLSMENEKPDTTKVPLKYNIQHEEMKAYRRKNDLEYIDQHFASSKSGISNGRNNNKEVNLTKAENVGIKKRRIMKNENNIYDFEDHSPVREKWGHRLRSRGAS",
    "output": "May be a histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code (By similarity). Represses transcriptional silencing by negatively affecting heterochromatin stability."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRVKILPLVFMTLLLIVPSQMLLPSGQANASTPGFIERVYTDKARYEPGELVTVTAQINNSGGTNWSGDVTMTIFHLENAVYSSVQHASIASGQTTDVTFSWTSDTTDFKGYFVSVDAGSLGQGYSSIDVSSDFAKYPRYGYISEFSSNETAAESAAKVNELAQDYKINAWQFYDWMWRHETMIKRTGGTIDPTWIDLFNRQISWPTINNQIAAIHNQNGAAMAYAMIYAARENYSGFGVNPEWGMYMDPAHTKQLDVDFGNNSTYMYLFDPANAGWQQFIHEQYLDAIQTANFDGIHIDQMGQRNNIYDYSGNSIDLATRFTPFIKAAKTKLTAANSNQDFMTFNIVDGTVNGWAANDVSKNANVDFLYSEIWHLSNSYMQLKDYIDSLRANSGNKAVVLAAYMNYGENIGDRYEAEDAALQHTAVNTDHAGYTGSGFVDQFADVNDSVTFTITAPEEGYYSLVFRFANHSGYTATRNLYVDSNFEIELPFQNQPNWDTWSHETWHQVYLTPGTHTIKLSYDSSNTGAINLDSLTLGTFDEHSIRLADAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSTLKSAMKDHYNFITAYENLLFDADVIDNDAGKQFINIAGVNTSPDGAANTVWHMSKRTPEYNILHLINLVNNDQNWRNSGNQPTAQTNLATKVYIGAEETITGVYAASPDHNQGATQSLPFTTGTDSSGSYISFTVPSLEYWSMIYMKRSTAAPVDNMYEAETAIKSNVSVNTNHAGYTGSGFVDQFATVNDGVSFIVHASSKDDYVLRFRYSNGGSDANRDVFLNGKYAGTVQLKHTGGWNQWAYGELTVPLAQGSHSVVLWYNSSNSGAVNLDHLKLDKTYIWQFDRQIASVPAGYRITFKAGLPGWVHFGTDNWKNVMDIPLASNGSSDSSLNYEASIGPFPSATTVDVTFLWDDNNNGILEDMIDRWEGTDFQIAIP",
    "output": "Produces cycloisomaltooligosaccharide from dextran."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTLQQKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGNKLRKLEFLAADALRQGADTLVTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTEQANYLTNGNRLLLDLFNVDVVMCEALNDPNQQLAELATRVEAQGFRPYVVPIGGSNALGALGYVQCSLEIAAQAAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPKVAQIQQALATSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTGKAMAGLLDGIEQQKFCDKGPILFIHTGGAPALFAYHPQV",
    "output": "Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAAARMLVLLASLCALLLTASAAKWTPAFATFYGGSDASGTMGGACGYGDLYGAGYGTRTAALSTALFNGGASCGACFTIACDTRKTQWCKPGTSITVTATNFCPPNYALSGDAGGWCNPPRRHFDMSQPAWETIAVYRAGIVPVNYRRVPCQRSGGIRFAVNGHSYFELVLVTNVGGSGAVAQMWIKGSGTGWMAMSRNWGANWQSNARLDGQALSFRVQADDGRVVTAADVAPAGWSFGATYTSSAQFY",
    "output": "May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. May be required for rapid internodal elongation in deepwater rice during submergence (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRHYEIVFMVHPDQSEQVPGMIERYTGAITGAEGKIHRLEDWGRRQLAYSINKLHKAHYVLMNVEASQEVIDELETNFRYNDAVIRSMVMRTKHAVTEASPMVKAKDERRERREDFANETSEETEAGDSEE",
    "output": "Binds together with S18 to 16S ribosomal RNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVDITAAELRAAEKIFGDRLDLAKRYVEHLATSGTERGLIGPREIPRLWSRHVLNCAVIESEIPQGSRVADVGSGAGLPGLCLAIARPDLELTLIEPLERRVIWLQEVVDDLGLDNVTVMRSRAELAVGHVEADVVTARAVSALTNLAGLTIPLLGGTGEVIAIKGRSAGEEIEKAAKAIRKLGGVETSVLTVGDNLLEEPTTVVRIVVNKPQKKS",
    "output": "Specifically methylates the N7 position of guanine in position 518 of 16S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASLLYFILFLLFVCISYYFTYYPTNKLQAAVMETDRENAIIIQRNDEIPTRTLDTAIFTDASTVASAQIYLYYNSNIGKIIMSLNGKKHTFNLYDDNDIRTLLPILLLSK",
    "output": "Component of the entry fusion complex (EFC), which consists of 11 proteins. During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MHLQTRAAVVTGAASGIGLALSARFARAGAGVVMADVDGDALHRRAAELTARGAQVTAVTADLTDPEVVERLADTAFDQLGDIDVVCNNAGVLGPVGQPLWEVPLERMRQVFEVNHWAHVLVARAFVPRLLERGRPAHLIHTASMSAFVVGAGSAAYAASKHADLAVARSLRADLRGTGVRVSVLCPGRVDTPMVQGLTAPRGAGGDTSVSAEDVAGLVWEALGSDRFYLFSNSDARIRLRDQFDDVWRHVSLPPPSPEEELWPAPKATTVTMNH",
    "output": "Catalyzes the oxidation of 1-deoxy-11-beta-hydroxypentalenic acid to 1-deoxy-11-oxopentalenic acid in the biosynthesis of pentalenolactone antibiotic."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEKQYRVLLYYKYVKIDEPEEFTAQHLKFCKELGLLGRILISEEGINGTVSGTVEQTEQYMNALKADPRFADMPIKIDEADGHAFRKMFVRHKKELVTLRLEDDVDPNVTTGKHLKPKDFYEQMQDPDTIVIDARNDYEYDLGHFRGAVRPDIEAFRELPDWIEEHKDMLEGKKILTYCTGGVRCEKFSGWLLKKGFEDVSQLDGGIVTYGKDPEVKGQMWDGQCYVFDERISVPVNRVEHVIIGKDYFTGEPCERYVNCANPACNKKMICTPENEYKYMRSCSHECRTNERNMYVKEHDMTQEEINERLALIEKEDHAAID",
    "output": "Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKLDLKILDARMRDYLPKYATTGSAGLDLRACLDAPVTLKPGDTALVPTGLAIHLADPGYAALILPRSGLGHKHGIVLGNLVGLIDSDYQGELMISTWNRGQTEFALNPFERLAQLVIVPVVQARFNLVDDFAQSERGAGGFGSTGRG",
    "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEPAIKYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTQASVKSLAPEELDAMGAGVILSNTYHLWLRPGEQIVKEAGGLHQFMNWKKGILTDSGGFQVFSLAKNRDITEEGVHFKNHLNGSKMFLSPEKAIQIENDLGPDIMMSLDECPPFFESYDYVSKSVARTSRWAERGLKVHQHPDYQGLFGIVQGAGFKDLREQSAKDLVSLDFPGYSIGGLSVGESKAEMNHVLDFTTPLLPENKPRYLMGVGSADALIDGAIRGVDMFDCVLPTRIARNGTCMTSHGRLVVKNAAYAHDFTPLDDNCDCYTCRNFTRAYIRHLIKADETFGLRLTSYHNLYFLLHLMKQVRQAIMDDNLLEFRQNFFEMYGFNDKNPKNF",
    "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKRDYYQVLGVAKNASDDEIKKAYRKLAMKHHPDRNPGNKDAEEHFKEAKEAYEMLSDSQKRAAYDQYGHAGVDPNMAGAGAQGFGGFADAFGDIFGDIFGQAAAGGRGGRSGPQVYRGADLRYSMEITLEQAAHGYDTQIRVPSWVSCEICHGSGAKPGTKPETCPTCNGSGAVRMSQGFFSIQQTCPKCHGTGTYIPEPCTHCHGAGKTKETKTLEVKIPAGIDDGMRIRSAGNGEPGINGGPSGDLYVEIHIKAHAVFERDGDDLHCQMPIPFTKAALGGEIEVPTLAGRATFTVPEGTQSGKTFRLRGKGIKGLRSSIAGDLYVHVQVETPVKLTDAQRDLLQQFEKSLVEGGARHSPQSKSWFDRVKSFFD",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MYTRNLLWLVSLVSAAPLYAADVPANTPLAPQQVFRYNNHSDPGTLDPQKVEENTAAQIVLDLFEGLVWMDGEGQVQPAQAERWEILDGGKRYIFHLRSGLQWSDGQPLTAEDFVLGWQRAVDPKTASPFAGYLAQAHINNAAAIVAGKADVTSLGVKATDDRTLEVTLEQPVPWFTTMLAWPTLFPVPHHVIAKHGDSWSKPENMVYNGAFVLDQWVVNEKITARKNPKYRDAQHTVLQQVEYLALDNSVTGYNRYRAGEVDLTWVPAQQIPAIEKSLPGELRIIPRLNSEYYNFNLEKPPFNDVRVRRALYLTVDRQLIAQKVLGLRTPATTLTPPEVKGFSATTFDELQKPMSERVAMAKALLKQAGYDASHPLRFELFYNKYDLHEKTAIALSSEWKKWLGAQVTLRTMEWKTYLDARRAGDFMLSRQSWDATYNDASSFLNTLKSDSEENVGHWKNAQYDALLNQATQITDATKRNALYQQAEVIINQQAPLIPIYYQPLIKLLKPYVGGFPLHNPQDYVYSKELYIKAH",
    "output": "Probably part of a deoxycholate transport system. Its expression in the presence of deoxycholate in a ygiS deletion mutant increases intracellular deoxycholate levels and decreases cell growth; higher expression in the presence of deoxycholate inhibits cell growth completely. Bile acid detergents such as deoxycholate are important for host defense against bacterial growth in the gall bladder and duodenum."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFEVNPVLNKLKELSERTELLRGYLDYDAKKERLEEVSAELEQPEVWNEPERAQALGKERSALESVVATIDVLTQGAEDVEMLVSLAVEGEDEETFHEAETEADALEKKLVDLEFRRMFSGQHDASDCYMDIQSGSGGTEAQDWADMVLRMYLRWGEAHGYKPELIECSDGDVAGIKSATIKFTGEYAFGWLRTETGVHRLVRKSPFDSGGRRHTSFCSAFVYPEIDEDVEIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTNTVTQCQNDRSQHKNKDQAMKQLKAKLYELEMMKQNAEKQALEETKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQSVLDGDLDKFIEASLKSGL",
    "output": "Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAVVLRGGITGGFLHHRRDASSVITRRISSVKAAGGGINPTVAVERATWLPGLNPPPYLDGNLAGDYGFDPLGLGEDPESLKWYVQAELVHSRFAMLGVAGILFTDLLRTTGIRNLPVWYEAGAVKFDFASTKTLIVVQFLLMGFAETKRYMDFVSPGSQAKEGSFFFGLEAALEGLEPGYPGGPLLNPLGLAKDVQNAHDWKLKEIKNGRLAMMAMLGFFVQASVTHTGPIDNLVEHLSNPWHKTIIQTLFTSTS",
    "output": "The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated . Seems involved in the function of the photosystem I in low light conditions, when other LHCA proteins are less abundant . Required, together with LHCA6, for the formation of a full-size NAD(P)H dehydrogenase-photosystem I supercomplex (NDH-PSI) that triggers cyclic and chlororespiratory electron transport in chloroplast thylakoids, especially under stress conditions (e.g. increased light intensity) (Probable) ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLMAGQRGAWTMGDVVEKSLEGPLAPSTDEPSQKTGDLVEILNGEKVKFDDAGLSLILQNGLETLRMENALTDVILCVDIQEFSCHRVVLAAASNYFRAMFCNDLKEKYEKRIIIKGVDAETMHTLLDYTYTSKALITKQNVQRVLEAANLFQFLRMVDACASFLTEALNPENCVGILRLADTHSLDSLKKQVQSYIIQNFVQILNSEEFLDLPVDTLHHILKSDDLYVTEEAQVFETVMSWVRHKPSERLCLLPYVLENVRLPLLDPWYFVETVEADPLIRQCPEVFPLLQEARMYHLSGNEIISERTKPRMHEFQSEVFMIIGGCTKDERFVAEVTCLDPLRRSRLEVAKLPLTEHELESENKKWVEFACVTLKNEVYISGGKETQHDVWKYNSSINKWIQIEYLNIGRWRHKMVVLGGKVYVIGGFDGLQRINNVETYDPFHNCWSEAAPLLVHVSSFAATSHKKKLYVIGGGPNGKLATDKTQCYDPSTNKWSLKAAMPVEAKCINAVSFRDRIYVVGGAMRALYAYSPLEDSWCLVTQLSHERASCGIAPCNNRLYITGGRDEKNEVIATVLCWDPEAQKLTEECVLPRGVSHHGSVTIRKSYTHIRRIVPGAVSV",
    "output": "Involved in B-lymphocyte antigen receptor signaling and germinal center formation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASRGITITTNKAITTSKSTLILKHDKFLPPRNMINEFPHDDVLRMCYRRHMRLKPFISQRSMIQTTYVDYVRYKYKNEDYPKKCRASGIAHKTPVQSVLQQAELSLRFCLQAVMQVKKGVSDERSVSNEIRLSRNMLKNILAIEHEKAKLIAQNPRQNYPILREAFSYISPTAHKSSLLLRFNALREFDRCLIRFNMCMGTKL",
    "output": "Involved in sporulation and maintenance of the mitochondrial DNA. Is probably involved in a pathway contributing to genomic integrity (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSPAPPPCGFAEAESTNTKSAPKFRSACNACHEVKLKCLGGQPCARCRNKQVECVYSHAARIGKPKGSRNKKTLERLRQAKAMSRPEETQGEETTSLTAVDASQAINCRALSGSTRRDSSPLPPPHSDTDSAEGGAEEELLDQEERDEAEKPPLVENPPNLNPLEQISPPREDFLDLLAHSSLLNNTQHDLQHPTADMVPDGLAGFPHASTSAADDLSWMTSPTKSLLSTTFPAIEDDLQDLQDPFLCSSWRSACLPPSSSRSSFHFPRFNHFAEDTMGLEYASGMDATRSLGDPPHAMARAGSFSTSGPGSSQEGSHFLSSRHSQSSGMYQPVPKRPSCSCLKLQASALCRIHLVDRSHADMRGDTVLATASTILDSCNALILCPSCATDYKFLLLAIMTVRILLCWLRGLSATRTQNDNANMKLTLGEYEISGEEEAIIKNMLVSRALEKVKIAVRRLRERVNSITIQEVGNCSESTQRWDLTYIRMCLDHMEKQVGC",
    "output": "Transcription factor that regulates sirodesmin production and contributes to virulence . Probably binds to the consensus motif TCGGN(3)CCGA found in the promoters of sirT, sirP, sirO, sirN, sirP, sirB, sirR, sirJ and sirQ ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKYAVIGDPVSHSLSPVMHQVNFKSLNMEDTYEALHIPTQDFHDIRHIIEDNHINGFNVTIPHKERIIPYLDEINDQAKAVGAVNTVKIINNKWIGYNTDGIGYVMGLKQVYPDLENAYVLILGAGGASKGIANELSKIVQPKLTIANRTMSRFETWDMDINAISLEQSEQYLDEFDIIINTTSAGLNNNDDIVISLDNLSSSTLVSDIIYIPYKTKFLKEAEFKGNTVYNGLDMFINQGAESFKIWTGKQPNILEMKYAVLNKLKGV",
    "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKLLWQVTVHHTWNAVLLPVVYLTAQVWILCAAIAAAASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDILWLAWWLREYIPTNSTCCGRCHAPMHMRGRYLVEVDQAAFQCSAPFIMDAPRDLNISEDRMAELKCRTPPMSSVKWLLPNGTVLSHASRHPRISVLNDGTLNFSRVLLIDTGVYTCMVTNVAGNSNASAYLNVSSAELNTPNFSFFTTVTVETTEISPEDITRKYKPVPTTSTGYQPAYTTSTTVLIQTTRVPKQVPVPSTDTTDKMQTSLDEVMKTTKIIIGCFVAVTLLAAAMLIVFYKLRKRHQQRSTVTAARTVEIIQVDEDIPAAAPAAATAAPSGVSGEGAVVLPTIHDHINYNTYKPAHGAHWTENSLGNSLHPTVTTISEPYIIQTHTKDKVQETQI",
    "output": "Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays an important role for auditory synaptic responses. Involved in the suppression of glioma."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKAIVKRRVEDKLYQNRYLVDPGRPHISVRKHLFPTPNLIALTQVCPAKCYQLNDRRQVIIVSDGCLECGTCNVLCGPDGDIEWTYPRGGFGVLFKFG",
    "output": "Could be a 3Fe-4S cluster-containing protein."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIKTLLRRMSSNTTIPTPNGSNHWTASKVRSTFLDYFKKQQHTYVPSSSVVPHNDPTLLFANAGMNQYKPIFLGTVDPASDFASLKRAANSQKCIRAGGKHNDLEDVGRDSYHHTFFEMLGNWSFGDYFKKEAIDYSWELLTKVYGLQEDRLYVTYFGGDEKQGLEPDLEAKNFWLKVGVPEDHILPGSVEDNFWEMGDQGPCGPCSEIHYDRIGGRNASALVNMDDPNVLEVWNVVFIQYNREADGNLRTLPNKHIDTGMGFERLVSILQNKYSNYDTDVFLPIFDKIREITGVRPYTGKFGNEDKDGIDTAYRVIADHVRTLTFAICDGGVPNNEGRGYVLRRILRRGSRYVRKYMNYPIGGFFQQLVDVVIEQNKEIFPEISSGAQDLKEILNEEELSFAKTLDRGEKLFEQYAIIASKTPEQTLSGKDVWRLYDTYGFPVDLTRLMAEEAGLKIDEEGFERAKEESREASKGSGTKDGKTLVKLDVHALSELDQNDAIPKTNDEFKYGLENVKAKVVGIYDGSKFVDSIEDPSIQYGILLDKTPFYAEQGGQEYDTGKLVIDGKSEFNVANVQVYAGYVLHTGNIVDGKLNVGDEIIATYDELRRWPIRNNHTGTHILNFALREVLGDGVDQKGSLVAPEKLRFDFSHKQAVTAKELEKIEAISNKYIKNNDKVYYKDVSLTKAKEINGLRAVFGETYPDPVRVVSIGVSVDDLLADPTNTKWHEISIEFCGGTHVAKTGDIKDLVIIEESGIAKGIRRIVAVTGHDAHHVQKVANEFEQEIDNASSLPFGVAKESKSKELGVALKKLSISVLDKQRLTEKFNKLDKSIKDNLKAKQKEETKKTLDVVNNWLNDKENASSFLVAHVPITANAKAITEAINLIKKQDKTKSIYLLTGETDKVAHGCYVSDEAIAKGINANELAKAVSENIGGKAGGKGNIVQGMGDKPQGINTAIEEVTKLFKEKL",
    "output": "Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTGKKRSASSSRWLHEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRK",
    "output": "Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTDTIFALATAAGRSAVAVVRVSGPRSSEIAAALCGRLPSPRLASVRTLKHNGVALDAALVLRFEKPASYTGEDSVEFHVHGGRAVVEALLAALSELGARLAEAGEFTRRAFENGKLDLAQAEGVADLIDAETEAQRRQALGQVGGALSQRYDRWRDLLVQALAMLEAAVDFPDEDLPEEVAERARPGLRQLSAELNAALADVSRGRRVRDGFRIALIGAPNAGKSTLLNGLAERDAAIVTDVAGTTRDVIEVPLVLGGYKVLVADTAGIRETADVIEAEGVRRAKAWAEAADLRLWVVDGFHVKQADARPEAIRVGDWLILNKTDIADADASAHVAERWAGEGLTVLHIAGTSAEGPEALRAALASHVADALSGAEFPAATRLRHAERLSEARSYLERALSDVGLEVELAAEDVRLAARALERISGRIDPEDVLGRVFSTFCIGK",
    "output": "Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MCPQPHADHAITRGDTGAAGGRNWSGPFRKTPGRLVGMTLIRAYQLTLSSFIGNSCRHLPTCSEYGFEAIARYGLWAGGWLTLFRVVRCGPGGTHGFDPVPDSLAPRQRWYTPWRYWQPRRKDA",
    "output": "Could be involved in insertion of integral membrane proteins into the membrane."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDMTPSEIVKKLDDYIIGQDDAKRAVAIALRNRWRRMQLDTELRQEITPKNILMIGPTGVGKTEIARRLAKLAEAPFIKVEATKFTEVGYVGKEVESIIRDLTDTAVKMVRHQAIEKMRDKAKELAQERILDILVSPARNSSGQVEGSQNTSTARQFFLEPLIKGELNEQEIEIDLAVTPVDIEIMSPPGMEEMTNQLQSMFQHMSSQKHKIRKMKIGDALKLLIDEEASKLVNPEELKQVAIHSVEQNGIVFIDEVDKICRHGSKSTSDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRFPIRVELKSLTPKDFERILTEPSASLTYQYKSLMKTEGIKIEFTKDGITSIAGAAGQVNENTENIGARRLHTILERVMEDISYNADKIKKKSITIDSKYVDTHLSKLINNEDLSRFIL",
    "output": "ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPYLVVDTGGFEPVAKDGILHQMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEALEVAYAGQPEEADDDDPSRGIKIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRRGKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKWDGLDDHARDRAKADLTRKLKFLDFAKSHYISAAKKTGIGALMRSVDDAYAAAMAKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPLIVIHGNALDAVTDTYKRYLENRFRETFSLTGTPLRIEFRSSNNPYADKG",
    "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGLGSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLGRTSGVAELLPGFQAGPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV",
    "output": "Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity). Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFILTMGLNHHTAPIDIREKLVFKESEEEMALVTLQQEKSILENVIISTCNRTEIIAVVDQIHTGRYYLKRFMANWFQMDMEKIEPYLFFHEESDAVNHLYKVTAGLDSLVLGETQILGQVKHAFEIAKQTATTGTLLNKLFREVVTFAKKVHHHTKINENAVSVSYAAVEVAKKLYGSLDNKKIVLVGAGEMSELALQNLAGSGIADITIINRTKSNAELLANQFQAKVGAYENMNEHLMLADIVLVSTSAAEPIIKQAAMQDLMEQKASSMLVIDIGLPRNVEHDCSYIPNFHLYDIDDLAGVVSANSLERQRIVLELEKTIEAEVRNFFEWEKQLGVVPVIRALREKALDMQEVTMTSLENKLPGLTEREYIQIGKHMKSIINQMLKQPISELKEMSVEEDATTSIEHFKRIFGLSETDVTVIEKEQAETRS",
    "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTLDPKIAARLKRNADGLVTAVVQERGSGDVLMVAWMNDEALARTLQTREATYYSRSRAEQWVKGATSGHTQHVHSVRLDCDGDAVLLTVDQVGGACHTGDHSCFDAAVLLEPDD",
    "output": "Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGTGYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVLYHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQQICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLCDAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGEHGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL",
    "output": "Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism (By similarity). May play a role in EPS8 signaling. Binds glutathione ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSNAKTLYEKVYDAHVAVAAKGETPILYIDRHLVHEVTSPQAFDGLREKGRNVRQVGKTFATMDHNVSTQTKDINASGEMARIQMETLSKNCEEFGVTLYDLNHKYQGIVHVMGPELGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQARAKTMKIEVKGKVTEGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLTMEGRMTVCNMAIELGAKAGLIAPDATTFDYITGRKFSPQGEDLTAAIEYWSSLKTDDDAKFDAVVSLDASEIKPQVTWGTNPGQVIAIDQPIPAPESFSDPVEKVSAEKALAYMGLEAGKSLTDYNVDKVFVGSCTNSRIEDIRAAAAVAKGNKVAAHVQALIVPGSEQVKAQAEKEGLDIIFKEAGFEWRLPGCSMCLAMNNDRLGPQERCASTSNRNFEGRQGRDGRTHLVSPAMAAAAAIAGHFVDIRTITEKA",
    "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTDDLNKVWPSGLTVAEAEEVHKQLILGTRVFGGMALIAHFLAAAATPWLG",
    "output": "Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDGEFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWDSTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGSLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR",
    "output": "Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVPEDVYQSKKSELLYLQKVTGLTDTLKAQLDELSKQVHQMHDNAECVSSVLKNWDSILNSISQATLSLLQYTENDYEVGAWSNGSRPEADKEPPLPETLVRVNVANESQE",
    "output": "Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPKITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEIFTELYREQQELDDIIQIAEKISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQRDLEKIYNKNRKKYTQQKLISKTIEGLMRKGYKYDKIKAKLEESGIADGTEEIE",
    "output": "Modulates RecA activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MANTKSALKQIRKNNLKRLQNKFVLKTTKTAIKKLKLESKKNLNAFPKISSLIDKLAKKKIIHKNKSNRIKSKLVKLIN",
    "output": "Binds directly to 16S ribosomal RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKIQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLSAATHGLDEEAESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGSIASKGKGGALAADIDIDTVGTEGWGEDAELQLDEDGFVEAPEGLGEDVLGKGQEEGGGWDVEEDLELPPELDVPSGVSGSAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGPYKQLFLQTYARGRTTYQALPCLPSMYSYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLCMEIERKKLPKETLDQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDACQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVTTVTEIGKDVIGLRISPLQFR",
    "output": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MCKQMNLEGLTTEARNEATKKIDQVSTLEMVTLINQEDQKVAQAIEKVLPQIAAAIDAAAERFKKGGRLIYCGAGTSGRLGALDAIELTPTYSVSPERAFGILAGGEKAMYQAIEGAEDSKELAIEDLTQHQLTARDVVIAIAASGRTPYAVSAIEYGKKVGALTISVTCNNQSPMNQLAEIGIAPIVGPEVITGSTRMKAGSAQKMVLNMFSTGIMVKVGNIYQNLMVNVQPTNEKLIQRATNIIKEAAEIEESQAKEYLEAAQLEVAPAIVMAKAHVDFQKAKQLLAEHDGRISEVLA",
    "output": "Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MENLKHIITLGQVIHKRCEEMKYCKKQCRRLGHRVLGLIKPLEMLQDQGKRSVPSEKLTTAMNRFKAALEEANGEIEKFSNRSNICRFLTASQDKILFKDVNRKLSDVWKELSLLLQVEQRMPVSPISQGASWAQEDQQDADEDRRAFQMLRRDNEKIEASLRRLEINMKEIKETLRQYLPPKCMQEIPQEQIKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKLQAGSIAIVRQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKDLTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGYQVKLAGFELRKTQTSMSLGTTREKTDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATGDIPFQGCNSEKIRKLVAVKRQQEPLGEDCPSELREIIDECRAHDPSVRPSVDEILKKLSTFSK",
    "output": "Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process . Does not have protein kinase activity . Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage . In addition to TNF-induced necroptosis, necroptosis can also take place in the nucleus in response to orthomyxoviruses infection: following activation by ZBP1, MLKL is phosphorylated by RIPK3 in the nucleus, triggering disruption of the nuclear envelope and leakage of cellular DNA into the cytosol.following ZBP1 activation, which senses double-stranded Z-RNA structures, nuclear RIPK3 catalyzes phosphorylation and activation of MLKL, promoting disruption of the nuclear envelope and leakage of cellular DNA into the cytosol (By similarity). Binds to highly phosphorylated inositol phosphates such as inositolhexakisphosphate (InsP6) which is essential for its necroptotic function ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALGDYEYEEIENRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILDADDEEDQNLKLLGEDEMDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDELDEDEEVFEDEEDFND",
    "output": "Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKPLIAIVGRPNVGKSMLFNRILREKSAIVDSTPGVTRDRHISPGEWQGKQFLLMDTGGYCPEGDVISMAMLEQTLMAIRDADIILFLADVRSGLTYDDLEISKLLQRTFQHKQIFFAVNKVETPQLSIDAESFVSTGFTKPYFVSARDGSGVAELLDDMLDSLPVQEKQLVEKDLPTNLAVVGRPNVGKSSFVNALLGANRLIVSDIPGTTRDAIDSRFTRKKQDFVLIDTAGLRKRTKIDAGIEYYSSLRTDKAIERCDVALVMIDARTGIENQDMKIINMAVERKRGVLLLINKWDLVEKDSKTSAHYEKEVRSHMGNLAYIPLLFISALTKKNLYRAIDTAQEISENRSRKITTSALNRFLEVALAEKHPSTKSGKELKIKYMTQIEAPWPVFAFFCNDPELLQTNFRKFLENKLREHFKLEGVTVSLRFFKK",
    "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MISQIDKAELLERFLHYVSFHTQSKPNAKHSPSSVGQMKLAMQLQKELIQLGLENVEVSKYAVVTAFLPANDPNLTKTIGLVAHLDTSPQCSGKNVRPEVIEEYRGGDIALGIGEEFISPVYYSFMQKLVGQTLIVTDGTTLLGADNKAGIAEIMTALSILQKENIPHCNIRVAFTPDEEIGLGIHYFPMEKFSCDWAYTIDGGEVGELEYENFNAATAKVRFFGRNIHTGYAKGKMLNALTLACEFQQVFPVDEVPEKTDGKAGFYHLEDFSGDIEQVELTYLIRDFDEQNFAQRKAFIKNQVEKFNAKKGLKKPIELEIQDSYQNMYDVVKNVPQSIELADRAMKAVGIKPNHKPIRGGTDGAFLASKGLACPNIFTGGYNFHSKHELVSLQGMENTVQVIIEMLKCKDL",
    "output": "Cleaves the N-terminal amino acid of tripeptides."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MADVLSVLRQYNTQKKEIVVKGDEVIFGEFSWPKNVKTNYVIWGTGKEGQPREYYTLDSILFLLNNVHLSHPVYVRRAATENIPVVRRPDRKDLLAYLNGETSTSSSIDRSAPLEIGLQRSTQVKRAADEILAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTILQSTGKNFAKNIFAILQSVKAREEGRAPEQRPAPNTAPTDPTLRNKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTLKSVTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTPIIIIPAATTSLITMLNAKDLLQDLKFVPSDEKKKQGCQRENETLIQRRKDQMQPGGTTVSVTVPYRVVDQPLKLMPQDWDRVVAVFVQGPAWQFKGWPWLLPDGSPVDIFAKIKAFHLKYDEVRLDPNVQKWDVTVLELSYHKRHLDRPVFLRFWETLDRYMVKHKSHLRF",
    "output": "Tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. May be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression. Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEQLPSNLQVLLQAAEYVERREREAEHGYASILPCDPATPGRRKRQRTNSNPDNVRSVHNELEKHRRAQLRRCLEQLKQQVPLSMENSRHTTLSLLHRAKQHIKKLEDQELRAKSLKEKLRADQQKLRQRLKRLLPPNTERIRTDSLDSSNLSSERSDSDQEDLEVDVEGIILSGNEGELFVSFSAGLEHSYSTPAHAWL",
    "output": "Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3' (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAGSPSRAAGRRLQLPLLSFLQGATAVLFAVFVRYNHKTDAALWHRGNHSNADNEFYFRYPSFQDVHAMVFVGFGFLMVFLQRYGFSSVGFTFLLAAFALQWSTLVQGFLHSFHGGHIHVGVESMINADFCAGAVLISFGAVLGKTGPAQLLLMALLEVVLFGINEFVLLHLLGVRDAGGSMTIHTFGAYFGLVLSQVLYRPQLEKSKHRQGLYHSDLFAMIGTIFLWIFWPSFNAALTSLGAGQHRTALNTYYSLAASTLGTFALSALVGEDGRLDMVHIQNAALAGRVVVGTSSEMMLTPFGALAAGFLAGTVSTLGYKFFTPILESKFKVQDTCGVHNLHGMPGVLGVLLGVLVAGLATHEAYGDGLESVFPLIAEGQRSATSQAMYQLFGLFVTLMFASVGGGLGGLLLKLPFLDSPPDSQCYEDQVHWQAPGATLSPLPTPAFQVPGEHEDKAQRPLRVEEADTQA",
    "output": "Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related derivative methylammonium across the basolateral plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism. May transport either NH4(+) or NH3 ammonia species predominantly mediating an electrogenic NH4(+) transport (By similarity). May act as a CO2 channel providing for renal acid secretion (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MHLLIPAAGMGRRMGSDRNKLRLMLHGKPLLAWTLLAAESSISISWIGIIGQLEDEPTWETLLNTLSLNKPVVFIEGGQTRQESVYNGLQALPPEAEQVLIHDGARCLATPELLDRCAHALHKYQGFVAAVPVKDTIKVVDTTHQIQGTPDRSQLWAAQTPQGFQVVPLKKCHEQGRQQGWEVTDDAALFEKLDLPVHIVVGEETNLKVTTPADLAIAELILEQRLQKNSQTDGFGS",
    "output": "Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGESTVLTAAVMSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFAEGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFIINPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQEQIVAVVGKEKAEVELLQVDADLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVKAEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVVDFLPKVHGSGLFTRGQTQALSILTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGETGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGTLALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITALQMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVDKIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAINRTKEIIAGLVREAKVGEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKIDEKGRVDASMKALIPRPPKPEKKEEKHD",
    "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKPSDGLEALQNLLGYRFGDEGLLHRALVHRSYLHENPHLDEKDNETLEFLGDAVLGLAISHFLLEQFPDYNEGELSRLRSAIVNERELTRIAVELNLGEYLLLGKGEEMTGGRRKASLLADSLEALLASIYLDGGLDAVLGVIKKLFDVYLRFEKREHVLKALDKDYKTQLQELTQARYKLTPVYVLDREEGPDHDKTFHMNVVLEGQVLAGGSGKSKKDAQQAAAEKALQIIAADSWSLD",
    "output": "Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVDIIKTNATFKAGKGNKGTLSFEIPAKQISSGIDQAFNKQKDKINIPGFRKGHVSKELFLARFGEEALYEDALNAILPDIYDQAVNEADITVVGQPQIIPDDLKHGGPSKIHAEVTLAPTVELGDYKGVEVEKESDEVSDKELNAELERLQKGEAELVPAKEDQVSEKGDTVVIDFDGSVDGKQFDGGKAQNFSLSLGSGQFIPGFEDQLVGHKAGDDVDVKVTFPKDYQAKNLAGKEAVFAVTIHELKKLETPALDNEFAKDVDDSVLVLEELKAKTKEKLAKDKAEKNKDAFEDAAIQKVVDGAKINPEKLPEEMINDDVSRQMQTFFNNLAGQGVKPEMYFQIPNQPGAVKATNDRRRTNRVKTNLVLEEIARVEKINPSNEEIDKEIKSLASEYNIKESEVEKSVSAGMLSHDLKVQQAVELIVNSAQAVEKK",
    "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MYAVIKTGGKQYRVATGEKLKVEQIPADIGQEITLDQVLSVGEGDQLKVGTPLVSGAVVKATVLAHGRHDKIKIFKMRRRKHYQKHQGHRQNYTEIRIEAITA",
    "output": "This protein binds to 23S rRNA in the presence of protein L20."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKNYKFTISFVGTNYSGWQYQPNVPTIQNEVEEKLYYIVNKKKPIKQKIRAIGCSRTDKGVHAIEFVFNVKMEFDKDLNFLRKALNSALPKDIKIHNIEEVPLEFNSRFDALKKTYIYKLFFDEKNSPFFQDRAMLVYKPTDLGKMMEISHLFLGYKDFRGFTKELEDENGYCSVENITFKVDYPLVEISITANRFLRYMVRRMVGTMLSYAQGLISIDDVNDFLKAKRVSNHTAKAHGLYLKKVYY",
    "output": "Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQDSLTLNPIARVDGTLNLPGSKSVSNRALLLAAQANGTTRLTNLLDSDDVRHMLTALGQLGVNYRLSADRRSCEIDGLGGPLRADEALTLFLGNAGTAMRPLAAALCLQAQDVTLTGEPRMKERPIGHLVDALRQGGAQIDYLEHEHYPPLRLRGGYQGGDITVDGSVSSQFLTALLMMAPLAPQNSCIRIKGELVSRPYIDITLALMKSFGIEVRHDNYQVFYLTGGSVYRSPGEYLVEGDASSASYFLAAAAIRGGTVRVTGIGRHSVQGDIRFADVLESMGATIRWGNDYIECSRASLHTIDMDMNHIPDAAMTIATTALFASGGTTTLRNIANWRVKETDRLTAMATELRKVGATVIEGEDYLTVTPSARLSAARIGTYNDHRMAMCFALVALSDTPVTILDPQCTHKTFPDFFARLSALSTPASPHSAP",
    "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSTAVQVDDVMRYRDSRFQTIAAKLLPTQYLVVDDDTALTTTLGSCVAACLRDPVLKIGGMNHFLLPEGQVGDGAPARYGSYAMELLINDMLKRGAHRKRIEAKVFGGANVLKGFTSNPVGTRNAEFVRQYLQAEHIPIIAEDLCGIHPRKVWFFPTTGRVVVQRLPHAHEAEVAAAESAVRARLSKAPVTGGVELFE",
    "output": "Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLGALLLSGAVHAAVQPLDSVVAIVDNDVIMKSQMDQRVREVQQTIAKRGSGVPPAEALQPQVLDRLILENLQLQMGERSGIRVSDEELNQAIGTIAQRNNMSVEQFRAALAHDGLSYNDAREQVRREMIISRVRQRRVAERIQVSQQEVKNFLASDMGKAQLSEEFHLANILIATPDSASSDAIQAAAVKAKGIYDQLKKGADFTRLAATSSSSENALEGGDMGWRKAAQLPPPFGDMLSSMPVGDVTPPARTPGGFIILKLLEKRGGQGQAQMRDEVHVRHILIKPSEIRNEEETKRLAQKIYDRIENGEDFAELAKSFSEDPGSALNGGDLNWVDPNSLVPEFRQVMSETPQGVLSKPFQTQYGWHVLEVLGRRSTDATDQAREQQALNVLRNRKYDEELQTWLRQIRDEAYVEIKLPGATQAAQ",
    "output": "Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRNSFKIMTALALGLFAMQANAKFKVVTTFTVIQDIAQNVAGNAATVESITKPGAEIHEYEPTPKDIVKAQSADLILWNGLNLERWFERFFQNVKDKPAVVVTEGIQPLSIYEGPYKDAPNPHAWMSPSNALIYIENIKNALVKYDPQNAAVYEKNAADYAQKIKQLDEPLRAKLAQIPEAQRWLVTSEGAFSYLAKDYNLKEGYLWPINAEQQGTPQQVRKVIDLVRKNNIPVVFSESTISAKPAQQVAKESGAKYGGVLYVDSLSAKNGPVPTYIDLLNVTVSTIVKGFGK",
    "output": "Part of an ATP-driven transport system for iron. Metal-binding component (Potential). Acts as an adhesin that promotes binding of H.influenzae to host laminin and vitronectin. In addition, interaction with serum vitronectin plays an important role in bacterial serum resistance."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAPQTSNLWILLLLVVVMMMSQGCCQHWSYGLSPGGKRDLDSLSDTLGNIIERFPHVDSPCSVLGCVEEPHVPRMYRMKGFIGSERDIGHRMYKK",
    "output": "Stimulates the secretion of gonadotropins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGEPQQVSALPIPPMQYIKEYTDENIRKSLAPKPPVPIKDSYMMFGNQFQCDDLIIRPLETQGIERLHPVQFDHKKELRKLLMSILVNFLDMLDILIRSPGSIRREEKLEDLKLLFVHMHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVVEMIQNCLASLPDDLPLPDGTVSVKTEPMDVQEPCTDHHEGPQGAAASVKEATIDKDAAMCGIIDEMT",
    "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAANAEPRRRPGVGVGVVVLSCEHPRCVLLGKRKGSFGAGSFQLPGGHLEFGETWEECAQRETWEEAGLHLKNVCFASVVNSFVEKENYHYVTILMKGEVDMTHDSEPRNMEPEKNESWEWVPWEEFPPLDQLFWALRCLKEQGYDPFKEDLNHLEGYRGEHLERTTKTP",
    "output": "May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine derivatives 6-thio-dGTP and 6-thio-GTP . Could also catalyze the hydrolysis of some nucleoside diphosphate derivatives (By similarity). Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low. Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides to prevent their incorporation into DNA, is unclear . Through the hydrolysis of thioguanosine triphosphates may participate in the catabolism of thiopurine drugs (By similarity). May also have a role in DNA synthesis and cell cycle progression by stabilizing PCNA (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKIDLNADLGEGCTSDAELLTLVSSANIACGFHAGDAQTMQACVREAIKNGVAIGAHPSFPDRKNFGRSAMQLPPETVYAQTLYQIGALATITRAQGGVMRHVKPHGMLYNQAAKEAQLADAIARAVYACDPALVLVGLAGSELIRAGKQYGLTTREEVFADRGYQADGSLVPRSQSGALIEDEEQALAQTLEMVQHGRVKSITGEWATVTAQTVCLHGDGEHALAFARRLRSAFAEKGIVVAA",
    "output": "Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVMSDPIADLLTRIRNANVVRHEVVEVPSSNIKKAIANIMLTEGYIRDLEEYRDGSVDMLRITMKYGQNKERIITGLKRISKPGLRVYCRKDETPKVLNGLGVAVVSTSKGIVTDREARKLGVGGEVLCYIW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSKASYVKFEVPQDLADKVLEAVRKAKESGKIKKGTNETTKAVERGQAKLVVIAEDVQPEEIVAHLPLLCDEKKIPYVYVSSKKALGEACGLQVATASAAILEPGEAKDLVDEIVKRVNEIKGKTSS",
    "output": "Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIQMQSTLEVACNSGARRVQCIKVLGGSHRRYAGIGDVIKVSVKEAIPRGKAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLNANLAPIGTRIFGPVTRELRTEQFMKIVSLAPEVL",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKSTPQHKTADFAELVCSNSLRGDALTNAVGLLKEEMRRLDSVILKSAEATRVPAGGALAVDREGFSQMVTELVTNHPLIEVIREEITEIPNDDITVIATGPLTSDALAEKIHALNGGNGFYFYDAAAPIIDVNTIDMTKIYLKSRYDKGEAAYLNAPMTKQEFMDFHDALVNAEEAPLNSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYQGPRDGEYKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQTFRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEEALVFPETTAIGSLPHYVTHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEKIAERALQDLAPYLDK",
    "output": "Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSGKIIDKVKVFMGFDVFEDEEVEEEETVEIEDELVPVMNSKRNKVVNIHTTTQMKVVLYEPTNFEEAPNIVDNLKNRKPVIINLENIEPDLAKKFFDFLNGAIYALDGNIQKVSSGIFILAPNNVDISGNIKEELKNKGVFPWQK",
    "output": "Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTSSSESTRKGLTKIATNRLQKEFMEWQTNPPSGFKHRVSDNLQRWIIEVHGVPGTLYANETYQLQVEFPEHYPMEAPQVIFQHPAPLHPHIYSNGHICLDVLYDSWSPAMRLSSICLSILSMLSSSSVKQKPKDNDHYLKNCKHGRSPKETRWRFHDDKV",
    "output": "Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPTINQLVRKGRASETTKSKSPALQDCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHMVRGSLDTQGVKDRRQARSKYGAKRAKAAK",
    "output": "With S4 and S5 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKQYAIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLGGNQLEERFPLHPRPLFVVAESGFGTGLNFLTLWQAFSQFRDAHPEATLQRLHFISFEKFPLTQADLALAHQHWPELAPWAQQLHAQWPLPLAGCHRLILDDGRVTLDLWFGDINELTGKLDESLNQKVDAWFLDGFAPAKNPDMWTQNLFSTMARLARPGGTLATFTSAGFVRRGLQEAGFTMQKRKGFGRKREMLCGVMAHALTFPSPTPWFTRSGSAKRDVAIIGGGIASALLSLALLRRGWQVTLYCSDEQPAQGASGNRQGALYPLLSKHDAAINLFFPSAFTFARRLYDALPVTFDHDWCGVTQLGWDEKSQHKIDQMLSLALPDALAVAVDPDQAQQETGVATHCRGITYPAGGWLCPAQLTAALLALAATQGLRRHYTHTLTALSRQATGWQLQFAEGKAVEHEVVVLANGHQINHVDQTRPLPVYSVAGQVSHIPTTPALSALRQVLCYDGYLTPQNPATHQHCIGASYHRGSEETAYREDDQQQNRQRLIDCFPDAAWAKEVDISEKAARCGVRCATRDHLPMVGNVPDYDATLAQYAALARQKDAAERAPVYPDLFMLGALGSRGLCSAPLCAEILAAQMSEEPIPMDADTLAALNPNRLWVRKLLKGKAVK",
    "output": "Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFTVVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPARDLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRRCLLCEQSAAVCARGKTHQLTDLLNRMEALLNDVDACNVN",
    "output": "Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "KGSSGMMSMVAAAIAANRTKKGASAQAIRKYVAAHSSLKGAVLNFRLRRALAAGLKSGALAHPKGSAGWVLVPKK",
    "output": "Linker histones are implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRIMEMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWNRNGPTTSTVHYPKVYKTYFEKIERLKHGTFGPVRFRNQVKIRRRVDINPGHADLSSKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKIAPLMVAYMFERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGIRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMVGILPDMTPNTEMSLRGVRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQDPTMLYNKMEFEPFQSLVLKAARGQYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPNEGTAGVESAVLRGFLILAKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN",
    "output": "Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription. Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA. Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVKSKEEIRAFAEHWLGKRLVTYQTDANGQPVNQILVEAATDIDKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKIAIDPLAGPMPYQGRELAFKLGLEGKQVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK",
    "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTTYSLRLKAKNELTPHPTAQYWRKCQVEELFDLPFMDLVFRAAEIHRQHFDPNAIQLSTLLSIKTGGCAEDCEYCPQSARYDTGVEKQSMLDVNYIVEKAQIAKARGASRFCMGAAWRGPKPKDIETVSAIIKAVKSLGLETCGTFGMLEEGMAEDLKEAGLDYYNHNLDTDPERYHQVIHTRSHDDRMDTLGKVRSAGLKICCGGIVGMNETRAERAGLIASLANLDPQPESVPINQLVKVAGTPLENAEDLDWTEFVRTIAVARITMPKSYVRLSAGRSNMPEAMQALCFMAGANSIFYGDKLLTTENPEEDGDRVLMEKLNLYPLSCSNVE",
    "output": "Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNPEEAMRPLLMASEMMMFGAGLVALIAGSFLRRQRQWWVGVMAAAAQVGVIGVAVVQMVGPDQMAFEGAFSVDTATGVARIACAAGLLLIWAVAGAEMRASPREAETYALLMFSATGVLVLAGAEDLLLLVAGYFLASIPLYGLVGLARSAAAAEAAMKAYLMGALFGILLMLGVTILYGLTGATRYPQLAMTLSGAPAVAVAAGVVGVLAGLMFEAGGVPAHFWVPDAAQGANATAATFLTTVPKIGALVALYRLTTVLPDTLAWPVLIAVFAVISMTLGNLAAYWQQDPRRLLGWSTVSQVGYLLVPITVAGASELALPSLLFYLGGYTVTNIAAFAVTAALPGRRDLDSYRGLARTRPWLAAALVVALLGLVGTPPTAVFIGKVTTAAAAWDGRYAWLAVVVFVNTLVSLFYYLRWIIPAFGRPHETGDADQSAVQHWPARVAVLAAALSLLLGIIAGPVWQLVT",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKVGFVGWRGMVGSVLMQRMKEENDFAHIPEAFFFTTSNVGGAAPDFGQAAKTLLDANDVAELAKMDIIVTCQGGDYTKSVFQPLRDSGWNGYWVDAASSLRMKDDAIIVLDPVNRNVIDNGLKNGVKNYIGGNCTVSLMLMALGGLFQNDLVEWATSMTYQAASGAGAKNMRELISGMGAIHAKVADELADPSSAILDIDRKVSDFLRSEDYPKANFGVPLAGSLIPWIDVDLGNGQSKEEWKGGVETNKILGRSDNPTVIDGLCVRIGSMRCHSQALTLKLKKDLPVSEIEAILAGANDWVKVIPNEKEASIHELTPAKVTGTLSVPVGRIRKLEMGGEYISAFTVGDQLLWGAAEPLRRVLRIVLGSL",
    "output": "Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAARAQAWLFAAALVIFHGSEYVLAAAFHGRRNVTATSLLISKQYVLAMSFAMLEHLTEALLFPELKEYWFVSYVGLVMVIIGEVIRKLAVVTAGRSFTHVIRIHYEDQHKLITHGVYRLMRHPGYSGFLIWAVGTQVMLCNPLSTVAFTLVLWRFFSKRIPYEEFFLRQFFGREYEEYAQKVHSGLPFIE",
    "output": "Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. Carboxyl methylation is a reversible and potentially regulated step in the post-translational modification of prenylated proteins (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRVLLQLGLLALGAVCVCAIPKQSATLRALVRETLTLLSTHRTLLKGNETLRISVPAHKNHQLCIEEIFQGIDTLKNQTTQGEALATLFQNLSLIKKHIDLQKQKCGEERRRVKQFLDYLQEFLAVINTEWTIEG",
    "output": "Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity). Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MHPRFQTAFAQLADNLQSALAPILADHHFPAMLTAEQVSTLKNTAGLDEDALAFALLPLAAACARTDLSHFNVGAIARGVSGNWYFGANMEFLGATMQQTVHAEQSAISHAWLRGEKGLAAVTVNYTPCGHCRQFMNELNSGLDLRIHLPGRAPHTLRDYLPDAFGPKDLEIKTLLMDEQDHGFTLTGDTLTQAAITAANKSHMPYSHSPSGVALECKDGRIFTGSYAENAAFNPTLPPLQGALNLLSLNGYDYADIQRAILAEKGDAALIQWDATAATLKALGCHNIDRVLLG",
    "output": "This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQRCSVVAALAGVVFLAQACSLSTPSRITHTDKLPVVVTFNALKELTQMVGGEKIHLVSIVPDGVDSHDFEPKAKHMAFISDAKVIVYNGLGMEPWIHSVLHAARNSGSIRVEAAQGIVPLKAHTRGHTAHHVHAHASHGSAYDPHVWLSVCNAQTMLRTIGKALCKADPQHTRFYKRNARNAAARLEALYKEYRSKFAALSHRYFVTTHAAFGYLCRDFDLQQKSIKDVFNTEEPSIKRLVELVEFSKKHSVRTIFSERGPSEKVARVLAQEIGASVETIYTMEKNEENLSYYERMKHNINRIYRACSKQVTPSQ",
    "output": "Part of an ATP-driven transport system TP_0034/TP_0035/TP_0036 for a metal. Metal-binding component."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MADTVLNSAPSKAAPRISFVSLGCPKALVDSERIVTRLRAEGYELTKTHQGADLVVVNTCGFLDSAKAESLNAIGEALAENGKVVVTGCMGAEPEQIREVHPSVLAITGPQQYESVLAAVHEAVPPAHDPFLDLVPAEGVKLTPRHYAYLKISEGCSNRCTFCIIPKLRGDLVSRPAGDVLREAERLVKAGVKELLVISQDTSAYGVDLRYATSPWGDKEVAARFLDLAGALGDLGAWVRLHYVYPYPHVDAVMELMAAGKVLPYLDIPFQHASPTVLKRMKRPASQEKTLARIQAWRAAVPDLTLRSTFIVGFPGETEAEFEELLGFLEEAEIDRAGCFKFEPVRGADANALENPVPDAVKAERYDRFMRTQQKVSARRLKRKVGTRQSVIIDTVTPDGGIGRTKGDAPEIDGTVKVFARRPLRVGEIATVKIEAAGPYDLSGTAVGF",
    "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSYNFTDPYEIARFIKEVKKSTPVKVYLKGNLEGVELGSIECYGNNDFYVLFGESDEVATFLTENKDKIVSFRLENDRRNSAIPMLELLNINARIEPGAIIRDRVSIGDNAVIMMGAVINIGAEIGESTMVDMNAVIGARGKLGKRVHLGAGAVVAGVLEPPSKTPCIIEDDVLIGANAVILEGVKIGKGSVVAAGSVVVEDVPAGVVVAGTPAKIIKSVDEKTKDKTEILDDLRK",
    "output": "Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFLLDANVLLAAHRGDHPNHRTVRPWFDRLLAADDPFTVPNLVWASFLRLATNRRIFEIPSPRAEAFAFVEAVTAQPHHLPTNPGPRHLMLLRKLCDEADASGDLIPDAVLAAIAVGHHCAVVSLDRDFARFASVRHIRPPL",
    "output": "Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB31 (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARKPDISAVPVESAACQGPDPRRWWGLVVILAAQLLVVLDGTVVNIALPSVQRDLGMSDTSRQWVITAYTLAFGGLLLLGGRVADAFGRRRIFAVGILGFGLASLLGGAAPDPGTLFLARALQGVFAAALAPAALALINTLFTEPGERGKAFGVYGAVSGGGAAVGLLAGGLLTEYLDWRWCLYVNAPVALLALLGCRLLPRDRRTGRAVRLDLPGTLLGCGGLVAIVYAFAEAESGWGDPLVVRLLVLGVLMLVAFALVERRVQDPLLPPGVVAHRVRGGSFLVVGLPQIGLFGLFLFLTYYLQGILDYSPVLTGVAFLPLGLGIAVGSSLIAARLLPRTRPRTLIVGALLAAAAGMALLTRLEPDTPQVYLTHLLPAQILIGLGIGCMMMPAMHTATARVAPHEAGAAAAVVNSAQQVGGALGVALLNTVSTGATAAYLADHGTSPAATVDGTVHGYTVAIAFAVGVLLLTAVLAWVLIDSRTEAADETGSASVTPARPR",
    "output": "May be involved in active puromycin efflux energized by a proton-dependent electrochemical gradient. In addition, it could be implicated in secreting N-acetylpuromycin, the last intermediate of the puromycin biosynthesis pathway, to the environment."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQTVLIALLRFYKLAVSPLLGSRCRFYPSCSDYAREAIQYHGAARGTYLAARRLCRCHPFSAGGVDLVPPPNSDARNAPHEAEASSHRL",
    "output": "Could be involved in insertion of integral membrane proteins into the membrane."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNNPSTPKAPLADYLAHLPLAEEERARLGESASFSELHARLAGEGAASEAGGDPALASVRARLQLGSPELDDAEMFGVDAQGRTFLKISPPIRRTKVIPEPWRTNILVRGWRRLTGRSNPPKPKRALPRARWQRVGSLRRFILLLLMLAQTSVATYYMKGILPYQGWAFVDLEELTRQSLLDTVQQVLPYVIQFGILALFAILFCWVSAGFWTALMGFWELLTGRDRYRISGSSAGSEPIAADARTAIVMPICNEDVPRVFAGLRATVESMAATGEMERFDFFVLSDTNDPDIAVAEQQAWLELCRETRGFGKIFYRRRRRRVKRKSGNIDDFCRRWGGDYRYMVVMDADSVMSGDCLAKLVRLMEANPEAGIIQTAPKASGMDTLYARMQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRMQPFIDHCALAPLPGKGSFAGAILSHDFVEAALMRRAGWGVWIAYDLDGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFFFLVLSTALLAVHQLMEPQYFLEPRQLFPIWPQWHPEKAIALFSTTLTLLFLPKLLSVMLIWAKGAKGFGGVIRVTLSMLLEMFFSVLLAPVRMLFHTRFVLAAFLGWSVQWNSPQRDDDATPWSEAIRRHGMQTLLGLAWTLLVAWLNPRFLWWLSPIVGSLMLSIPVSVISSRVKLGLRARDEKLFLIPEEYDTPRELRATDEYTYENRWHALKDGFLKAAVDPLLNALACAMGTARHNRAQAIETVRGERIGKAIEKGPEQLDGATRLALLSDPVALSRLHAQVWEENRDDWLGRWRKAEADDPHAASVPLAQVVPGDAGLLPAAQS",
    "output": "Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGEDDFYLFQNISSVGPWDGPQYHLAPVWAFRLQAAFMGFVFFVGTPLNAIVLVATLHYKKLRQPLNYILVNVSLGGFLFCIFSVFTVFIASCHGYFLFGRHVCALEAFLGSVAGLVTGWSLAFLAFERYVVICKPFGSIRFNSKHALMVVLATWIIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSEYYTWFLFIFCFIIPLSLICFSYSQLLRTLRAVAAQQQESATTQKAEREVSHMVVVMVGSFCLCYVPYAALAMYMVNNRNHGLDLRLVTIPAFFSKSSCVYNPIIYCFMNKQFRACILEMVCRKPMADESDVSGSQKTEVSTVSSSKVGPH",
    "output": "Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal (By similarity). Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors . Involved in ensuring correct abundance and localization of retinal membrane proteins . May increase spectral sensitivity in dim light ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKYVGAHVSAAGGVENAPLAAARIRARAFALFTKNQRQWRAAPLKEESITAFKRNCADHGYRPDHILPHDSYLINLGHPEADNLKKSRTAFFDEMKRCEQLGLKFLNFHPGSHLGKISEDACLSRIAESVNMALDRTASVCAVIENTAGQGTNLGHRFEHLARVIDQVEDKTRVGVCLDTCHTFAAGYDLRTASTYEATLKAFDRVVGLKYLRAVHLNDSIKGLASRVDRHQSLGQGALGLDVFRRIMNDRRFENMPLILETKDATIWEQEIKLLYGMIKGAK",
    "output": "Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKPAARETRTPPRSPGLRWALLPLLLLLRQGQVLCAGAAPNPIFDIEAVVSPTSVLLTWKHNDSGASECRIENKMESNLTFPVKNQTSCNITGLSPGTSYTFSIISVTTNETLNKTITTEPWPVSDLHVTSVGVTQARLTWSNANGTASYRMLIEELTTHSSVNISGLKPGTNNSFAFPESNETQADFAVAEEVPDANGTKRIPVTNLSQLHKNSLVSVDPPSGQDPSLTEILLTDLKPDTQYNATIYSQAANGTEGQPRNKVFKTNSTQVSDVRAMNISASSMTLTWKSNYDGSRTSIVYKIHVAGGTHSVNQTVNKTEAIILGLSSSTLYNITVHPFLGQTEGTPGFLQVYTSPDQVSDFRVTNVSTRAIGLAWRSNDSKSFEIFIKQDGGEKHRNASTGNQSYMVEDLKPGTSYHFEIIPRGPDGTEGLSSTVNGSTDPSAVTDIRVVNISTTEMQLEWQNTDDASGYTYHLVLESKSGSIIRTNSSQKWITVGSLTPGTLYNVTIFPEVDQIQGISNSITQYTRPSSVSHIEVNTTTTTAAIRWKNEDAASASYAYSVLILKTGDGSNVTSNFTKDPSILIPELIPGVSYTVKILTQVGDGTTSLVPGWNLFCTEPEPVTSFHCEVVPKEPALVLKWACPFGMYTGFELGVRSDSWDNMTRLENCTSDDDTECRTEVAYLNFSTSYNISIATLSCGKMALPAQNICTTGITDPPTPDGSPNITSVSHNSVKVKFSGFEASHGPIKAYAVILTTGEAAQPSADVLKYTYEDFKRGASDTYVTYLIRIEEKGQSQGLSEVLNYEIDVGNQSTTLGYYNGRLEPLGSYRACVAGFTNITYNLQNDGLINGDESYVSFSPYSEAVFLPQDPGVICGAVFGCIFGALAITAVGGFIFWRKKRTDAKNNEVSFSQIKPKKSKLIRVENFEAYFKKQQADSNCGFAEEYEDLKLIGISLPKYTAEIAENRGKNRYNNVLPYDISRVKLSVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQGRTKCEEYWPSKQAQDYGDITVAMTSEVVLPEWTIRDFVVKNMQNSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIRAQKDSKVDLIYQNTTAMTIYENLEPVSMFGKTNGYIA",
    "output": "Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2 (By similarity). Plays a role in cell adhesion, migration, proliferation and differentiation . Involved in vascular development . May be involved in the mechanism of contact inhibition of cell growth . Regulator of macrophage adhesion and spreading . Positively affects cell-matrix adhesion . Positive regulator of platelet activation and thrombosis . Negative regulator of cell proliferation (By similarity). Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR . Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation (By similarity). Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation (By similarity). Enhances the barrier function of epithelial junctions during reassembly (By similarity). Negatively regulates T-cell receptor (TCR) signaling (By similarity). Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEEEERPRKIQKLGSSEAHESEPLITGAIKGSQDDTSPAEQTNSQKAIPGATTDNSKESEEPASSTATDGPETTEQKISKRQLRRQAKLEQWEAKREERKIIRKQKTAARKERRRELWEEAKREGKDPNEELNKLFPMTTRTRHRKSTRLPLTLIIDCGFDDLMQDKERVSLGQQLTRSYSENNKSAFNGHLIISSFNKKLKERFETVLHKTHEGWKGVRFTGEDWLQAAKEASEVMQGPNGGKLVGPFEDKTDAKPEDGEIVYLTSDSSETLTELKPYSTYIIGGLVDKNRHKGICHKRATELGIRTAKLPIGQYIQMNSRPVLATNHVVEIMVRWLQLRDWAEAFMQTLPPRKGGALKDSVKGQRDSTPRDDVESNTEKGTVSETVEDTEATEPAEAVTPKDIDAVQENKQDE",
    "output": "S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ",
    "output": "Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRLLDDLQAGLAAIDAAHLRRVRRTAYSPTDRSQRISVPGEAPRDILGFCGNDYLGLAAHPALVEAMTQGTQQYGFGSGASHLVSGHSIAHARLEARMAALQGEHIPEADALFFCTGYMANLAVVSAMAQAGGIRPAEECTIFSDALNHASLIDGARLSRAPIKVYPHVDLAALEALLAASTSRNKLIVTDGVFSMDGDIAPLPELLALAERYDAWLIVDDAHGLGVLGENGAGVLSHFGLHSQRIIYVGTFGKAAGGSGAAIVGHRLVIDWLVQRARTYIFTTATPPGIACAVEAALDLIASEEGDERRARLDRHIAVWSAHAQRLAARFGWQWMPSPTAIQPIVIGENAPALALAAALEHEGIRIAAIRPPTVPAGTARLRITLSAAHTDADIERLAQALEAAGQSLQPAKAA",
    "output": "Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQPPPMRERQRWRPEEDAILLAYVRQYGPREWSLVSQRMNRPLHRDAKSCLERWKNYLRPGIKKGSLTDDEQRLVIRLQAKHGNKWKKIAAEVPGRTAKRLGKWWEVFKEKQQRELRDRDRRRLPPPLDGDERGCAGGRYDWLLEDFADKLVNDHHRRMMAAPILPPWMSSSPSSSSSPSVTLSLASAAVAPAPAAPPPTWGGGGGGEVVVAELMECCREMEEGQRAWAAHRKEAAWRMKRVEMQLETERACRRREATEEFEAKMRALREEQAAAVERVEAEYREKMAGLRRDAEAKEQKMAEQWAAKHARLAKFLDQVAACRRWPPVEINGGGGGGPGGGR",
    "output": "Transcription factor required for normal cell differentiation. May interact with other proteins to repress the knox homeobox genes (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTTYGSFPGARPRRLRTTPVMRRMVAETRLHPADFILPAFVREGVSEPVPIAAMPGVVQHTRDTLKKAAAEAVEAGVSGIMLFGVPEDGKKDAAGTAGTDPDGILQVALRDVRAEVGDELLVMSDLCLDEFTDHGHCGVLDGQGRVDNDATLERYAEMAQVQADAGAHVVGPSGMMDGQIGVIRDALDQIGREDVAILAYTAKYASAFYGPFREAVGSSLKGDRKTYQQDSANARESLRELALDLEEGADMVMVKPAGPYLDILAKVAEASDVPVAAYQISGEYSMIEAAAEKGWIDRDRAILESLTGIKRAGARNILTYWATEVARTLR",
    "output": "Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDASKSKALEAALSQIDRQFGKGTVMRLGDKGREKMPAISTGSLGLDVALGIGGLPKGRIVEIYGPESSGKTTLTLQVIAEAQRQGGTCAFVDAEHALDPVYAEKLGVNVDDLIISQPDNGEQALEVADMLVRSGAVDVLVVDSVAALTPKAEIEGDMGDHHVGLQARLMSQALRKITGNIKNANCLAIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRIGSVKEGDEVVGSDTRVKVVKNKVAPPFKQAEFQILYGQGINRLGEIVDFGVKLGLIDKAGAWYSYNGDKIGQGKANAMQYLRDNKEVAEFLEQKIKAELLGDIKPVAKEGAEVEEESAEQE",
    "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSTEYRTGREGEFTYRGHDLDELQEMSLEDVAELLPARQRRTITRGLSEEHHKVLAEARESGTEETANNPIRTHLRDMPVLPEFVGLTFAVYTGQEFERVEVQPEMIGHYLGEFQLTRSSVEHGQAGIGATRSSKFVPLK",
    "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKFELDTTDGRARRGRLVFERGTVETPAFMPVGTYGTVKGMTPEEVRATGADILLGNTFHLWLRPGEEIMRKHGDLHDFMNWQRPILTDSGGFQVFSLGDIRKITEEGVHFRSPINGEKIFMDAEKSMQIQYSLGSDVVMIFDECTPYPATHDEARKSMQMSLRWAQRSRDEFDRLENPNSLFGIIQGSVYEDLRDESLKGLLEIGYDGYAVGGLAVGEPKEDMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGVDMFDCVMPTRNARNGHLFTSEGVIKIRNARHRDDTSPLDAKCDCYTCKNYSRAYLYHLDRCNEILGARLNTIHNLRYYQMLMEGLRGAIETGTLDAFVEEFYTSQGREVPKLSD",
    "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLTHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK",
    "output": "Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQTNNAASASASNST",
    "output": "Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1 . Requires primed phosphorylation of the majority of its substrates . In skeletal muscle, contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis . May also mediate the development of insulin resistance by regulating activation of transcription factors . Regulates protein synthesis by controlling the activity of initiation factor 2B (EIF2BE/EIF2B5) in the same manner as glycogen synthase . In Wnt signaling, GSK3B forms a multimeric complex with APC, AXIN1 and CTNNB1/beta-catenin and phosphorylates the N-terminus of CTNNB1 leading to its degradation mediated by ubiquitin/proteasomes . Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA . Phosphorylates NFATC1/NFATC on conserved serine residues promoting NFATC1/NFATC nuclear export, shutting off NFATC1/NFATC gene regulation, and thereby opposing the action of calcineurin . Phosphorylates MAPT/TAU on 'Thr-548', decreasing significantly MAPT/TAU ability to bind and stabilize microtubules . MAPT/TAU is the principal component of neurofibrillary tangles in Alzheimer disease . Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex . Phosphorylates MACF1, inhibiting its binding to microtubules which is critical for its role in bulge stem cell migration and skin wound repair (By similarity). Probably regulates NF-kappa-B (NFKB1) at the transcriptional level and is required for the NF-kappa-B-mediated anti-apoptotic response to TNF-alpha (TNF/TNFA) (By similarity). Negatively regulates replication in pancreatic beta-cells, resulting in apoptosis, loss of beta-cells and diabetes (By similarity). Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation (By similarity). Phosphorylates MUC1 in breast cancer cells, decreasing the interaction of MUC1 with CTNNB1/beta-catenin . Is necessary for the establishment of neuronal polarity and axon outgrowth . Phosphorylates MARK2, leading to inhibition of its activity (By similarity). Phosphorylates SIK1 at 'Thr-182', leading to sustainment of its activity . Phosphorylates ZC3HAV1 which enhances its antiviral activity . Phosphorylates SNAI1, leading to its BTRC-triggered ubiquitination and proteasomal degradation . Phosphorylates SFPQ at 'Thr-687' upon T-cell activation . Phosphorylates NR1D1 st 'Ser-55' and 'Ser-59' and stabilizes it by protecting it from proteasomal degradation. Regulates the circadian clock via phosphorylation of the major clock components including BMAL1, CLOCK and PER2 . Phosphorylates FBXL2 at 'Thr-404' and primes it for ubiquitination by the SCF(FBXO3) complex and proteasomal degradation (By similarity). Phosphorylates CLOCK AT 'Ser-427' and targets it for proteasomal degradation . Phosphorylates BMAL1 at 'Ser-17' and 'Ser-21' and primes it for ubiquitination and proteasomal degradation . Phosphorylates OGT at 'Ser-3' or 'Ser-4' which positively regulates its activity. Phosphorylates MYCN in neuroblastoma cells which may promote its degradation . Regulates the circadian rhythmicity of hippocampal long-term potentiation and BMAL1 and PER2 expression (By similarity). Acts as a regulator of autophagy by mediating phosphorylation of KAT5/TIP60 under starvation conditions, activating KAT5/TIP60 acetyltransferase activity and promoting acetylation of key autophagy regulators, such as ULK1 and RUBCNL/Pacer . Negatively regulates extrinsic apoptotic signaling pathway via death domain receptors. Promotes the formation of an anti-apoptotic complex, made of DDX3X, BRIC2 and GSK3B, at death receptors, including TNFRSF10B. The anti-apoptotic function is most effective with weak apoptotic signals and can be overcome by stronger stimulation . Phosphorylates E2F1, promoting the interaction between E2F1 and USP11, stabilizing E2F1 and promoting its activity . Phosphorylates mTORC2 complex component RICTOR at 'Thr-1695' which facilitates FBXW7-mediated ubiquitination and subsequent degradation of RICTOR . Phosphorylates FXR1, promoting FXR1 ubiquitination by the SCF(FBXO4) complex and FXR1 degradation by the proteasome (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPVNNKDINILGIETSCDETSAAVLRNGCELLSHIISSQIKTHQKYGGVVPEVASREHILHLQSVVEQALQEAKMGFGDLAGIAVTYGPGLVGSLLVGVAGAKAMAYGAGIPLLGVNHLEGHIYANFLHNPGLKFPLLALLVSGGHSHLVYFEGHGKYQVLGQTRDDAAGEALDKVARTLGLGYPGGPYIQKAALEGNPHAYEFPRAMLEPGSLDFSFSGVKSAVLNTLNSARMKGETVNVADVAASFQEAIVDVLVRKTLLALARTKAPTLVLAGGVAANTLLRERLTEATQKRGIAFSYPPPILCTDNGAMIATAGYYRYLDKDYAPWNLNAIPGLNLA",
    "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATLIPVNGGHPAASGQSSNVEATYEDMFKEITRKLYGEETGNGLHTLGTPVAQVATSGPTAVPEGEQRSFTNLQQLDRSAAPSIEYESSAAGASGNNVATTQANVIQQQQQQQQQAESGNSVVVTASSGATVVPAPSVAAVGGFKSEDHLSTAFGLAALMQNGFAAGQAGLLKAGEQQQRWAQDGSGLVAAAAAEPQLVQWTSGGKLQSYAHVNQQQQQQQQPHQSTPKSKKHRQEHAAELIYASPSTSANAAQNLAQSTPTSAPSNSSGGSTSSSGGGGGRKKAAQAAAAAAAANGVHIQKRYACTHCPYSTDRRDLYTRHENIHKDEKPFQCYACLKQFNRADHVKKHFLRMHRELQYDINKTRRHVSAGSGSSGSGSSGSGSHHSGGRGNVTINSAGVNIDNAFLEAQRHPTSSSMSIVETIEAVASATDMPLAQLKQEKMDDGAGVVLPLHVGVMQQPVASSSSGSSGSHGGNGNGGSGSGLLKPKREKRFTCCYCPWSGADKWGLKRHLNTHTKPFVCLLCDYKAARSERLATHVLKVHNKRACSKCSYLADTQEEYQAHMSDVHGNVGNANGGGGAVTIYTTTTNEGVAGGGGGGGGGISGNISGGGPLQEIIVNPSSMVGWRLSANGSLIPPHDLLTGGLPNAATQKRGSERLFQYLEAEGSDPEDYARLLKMDAISRNTASVAQDFHKAGGVHELKIPANHQLLFNNKLPSQWTTREAAALLYSLSNMGGGSASSVSGSQRQKFGMRARQHSTGEDDENTPSSASSSSFSGDEFNMSATSPLKLSRHAIKLEKMDEMDAKDMGPTKAMMATAFLEAANYEQTAIELLASKRKIKVENDNDEDQENQQHQPHQQHHSQQQQQQRLQLIKSSPAYKLNNNNNNNSNNNNYYKDKTSHRNAVHHHRQDDKENNKTKSPGTAAVSVAAAAATSPPSISGPSNQTPFLTQMEYQNLNRIGTQFQNYVKDIINKYYAAETPLMLAAAAAALPTATTTGQQQQPELDIENLSPSKRRRLLSETEEYIEYLRNKEDITLTIAPKVQPPAPVTSLLKRQLDLSTPRRSPKKAAPAHSNSASNASRKSLNQLATLLPLLADAASQQEYLAAPLDFSKKSSSRKQAQPKKIRLTPEAVVTLLRDKYLNRMVRQRLGCLKCNQLRKNSSISFNYHTLGSLALHKYWRHGRLGSSSTRREKLQAALQKRISRGQADKC",
    "output": "Probable transcription factor involved in the development of the adult pattern of macrochaetae. Required for accumulation of achaete (ac) and scute (sc) in proneural clusters. Probably acts by binding to the proneural cluster-specific enhancers of the ac/sc complex and increasing enhancer efficiency, thereby acting as a stimulator of ac/sc expression in proneural clusters. Also required for correct development of the embryonic/larval peripheral nervous system (PNS)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSIVKVRNIFLIGPMGAGKSTIGRALAKELKLEFYDSDEVIEERAGADISWIFDIEGEEGFRRREQKVIDELTQKTNIVLATGGGVVITPENRNALAGRGTVIYLKTSLQQQFERTKRDTKRPLLQTEDLEGRLESLRDEREPFYDELADVSFETDKLTVKAVANNIIKYLYGEV",
    "output": "Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSNNSRHYSAIDEAILQGQAMLETLFGKPVAQRENPAKGLSQPALTSAEKKQSIGFMRVNHSGEVCAQALYHGQMATAKNPAVRALFTTAAKEETDHLAWCQERLEELGGHTSYLNAFWYTNSFLIGLLAGLSGDPLSLGFVEETEKQVEIHLADHLRKIPSSDLKSRKIVEYMQQDEIQHGLNARSSGAKELPYLVKKLMAFHAKVMTTLAYWI",
    "output": "Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKTVIASSLAVALGVTGYALTTDNSAHASESTTNYAQLANLAQNNPSELNAHPVQAGAYNITFVKDGFKYNFTSDGQSWSWNYTYVGGADTVATTQAAPAAQSTDYSASYSNEASTQSVSSNQQSSNTNVEAVSAPKTTSYSASTSSSSSASTGGSVKEQFLANGGTEAAWNAIVMPESGGNPNAVNPAGYRGLGQTKESWGTGSVASQTKGMINYANSRYGSLDAAIAFRDNHGWW",
    "output": "Is able to cleave peptidoglycan."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKMMNGEDANDQMIKESFFITHGNPILTVEDTHPLRPFFETWREKIFSKKPKAILIISGHWETVKPTVNAVHINDTIHDFDDYPAAMYQFKYPAPGEPELARKVEEILKKSGFETAETDQKRGLDHGAWVPLMLMYPEADIPVCQLSVQPHLDGTYHYNLGRALAPLKNDGVLIIGSGSATHPLDETPHYFDGVAPWAAAFDSWLRKALINGRFEEVNIYESKAPNWKLAHPFPEHFYPLHVVLGAAGEKWKAELIHSSWDHGTLCHGSYKFTSA",
    "output": "Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLGDDEWRETAWGASHHSMSQPIMVQRRSGQGFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGNFGTRDAETDGPEKGDQKGKASPFEEDQNRDLKQGDDDDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPNTNPSEGLGPLPNPTANKPLVEEFSNPETQNLDAMEQVGLESLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTASQQAASQAQPGQQQVLRAGAGQRPLTPNQGQQGQQAESLAAAAAANPTLAFGQGLATGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTASSLTGSTNGLFRPIGTQPPQQQQQQPSTNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSTSLGFGSGNSLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLIGHIVEFSQDQHGSRFIQQKLERATPAERQMVFNEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML",
    "output": "Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE) (, PubMed:21397187). Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation . Also mediates deadenylation-independent repression by promoting accessibility of miRNAs . Acts as a post-transcriptional repressor of E2F3 mRNAs by binding to its 3'-UTR and facilitating miRNA regulation . Plays a role in cytoplasmic sensing of viral infection . Represses a program of genes necessary to maintain genomic stability such as key mitotic, DNA repair and DNA replication factors. Its ability to repress those target mRNAs is regulated by the lncRNA NORAD (non-coding RNA activated by DNA damage) which, due to its high abundance and multitude of PUMILIO binding sites, is able to sequester a significant fraction of PUM1 and PUM2 in the cytoplasm . May regulate DCUN1D3 mRNA levels . May support proliferation and self-renewal of stem cells. Binds specifically to miRNA MIR199A precursor, with PUM1, regulates miRNA MIR199A expression at a postranscriptional level ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPRALWTAWVWAVISLSTEGASDQASSLSCDPTGVCDGHSRSLNSIPSGLTAGVKSLDLSNNEITHVGNRDLQSCVNLKTLRLGANEIHTVEEDSFFHLRSLEYLDLSYNRLSNLSSSWFRSLYVLKFLNLLGNLYRTLGETSLFSHLSNLRTLKVGNSNSFTEIHEKDFTGLTFLEELEISARNLQIYAPKSLKSIQNISHLILHLKQPVLLLDILVDIVSSLDYLELRDTNLHTFHFSEASISEMNTSVKKLIFRNVQFTDESFVEVVKLFNYVSGISEVEFDDCTHDGIGDFRALALERTRYLGNVETLTIRKLHIPQFFLFQDLSSIYSLTGKVKRVTIENSKVFLVPCLLSQHLKSLEYLDLSENLMSEETLKNSACEHAWPFLQTLVLRQNRLKSLEKTGELLLTLKNLTNLDISKNNFLSMPETCQWPGKMKQLNLSSTRIHSLTHCLPQTLEILDVSSNNLDSFSLILPQLKELYISRNKLKTLPDASFLPVLSVMRISRNIINTFSKEQLDSFQQLKTLEAGGNNFICSCDFLSFMQGQQALARVLADWPDDYWCDSPSHVRGQRVRDARLTLSECHRTAVVSAVCCALFLLLLLTGVLCHRLHGLWYMKMMWAWLQAKRKPRKAPRRDICYDAFVSYSERDSYWVENLMVRELEHFDPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTIFVLSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIDKKAIPQRFCKLRKVMNTKTYLEWPMDETQQEGFWLNLRAAVRS",
    "output": "Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATRGANVIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMRFLLDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERDESIRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADARLEDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQEQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSLITPPPHCRPSNEEEVRQFFWLADVVV",
    "output": "Blue light-dependent regulator that is the input of the circadian feedback loop. Has no photolyase activity for cyclobutane pyrimidine dimers or 6-4 photoproducts. Regulation of expression by light suggests a role in photoreception for locomotor activity rhythms. Functions, together with per, as a transcriptional repressor required for the oscillation of peripheral circadian clocks and for the correct specification of clock cells. Genes directly activated by the transcription factors Clock (Clk) and cycle (cyc) are repressed by cry. Necessary for light-dependent magnetosensitivity, an intact circadian system is not required for the magnetoreception mechanism to operate. Required for both the naive and trained responses to magnetic field, consistent with the notion that cry is in the input pathway of magnetic sensing."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI",
    "output": "Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLKVGLTGGIGAGKSEVSRLLVEHGAVLIDADRIAREVVAPGTPGLAAVVEAFGTDVLAPDGSLDRPKLGSIVFADPDKLAVLNAIVHPLVGARSRELETAAAADAVVIHDVPLLAENGLAPLYDLVVVVDASPETQLDRLVRLRGMTEQDARARMAAQATREKRLAIADIVMDNDVPLEELERRVGDVWADLVHRAHQPGESQE",
    "output": "Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSHPALTQLRALRYFKEIPALEPQLLDWLLLEDSMTKRFEQQGKTVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSGPELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLPASPLY",
    "output": "Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MANSAQARKRARQAAKANSHNSALRSKFRTAIKAVRKAIDAGDQAKAAELFKAATKTIDTIADKKIVHKNKAARHKSRLSAAVKGLQAQAAQ",
    "output": "Binds directly to 16S ribosomal RNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVNKRMQTLLMQLRQQGIQDERLLQALEAVPRERFVDEALSHKAYENTALPIGSGQTISQPYMVARMTELLQLTPTSRVLEIGTGSGYQTAILAHLVEHVCSVERIKGLQWQAKRRLKQLDLHNVSTRHGDGWLGWASRGPFDAIIVTAAPPEIPNALLEQLDEGGILVLPVGEQAQTLKCVQRRNNEFKVETVEAVRFVPLVKGELA",
    "output": "Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMLFDGVKRLFHIRGKLRKKVWINTSDIILVGLREYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDIDDI",
    "output": "Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKVGTGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPKEICKVLDDYVIGQGHAKKVLSVAVHNHYKRLNHQTKHNDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQSADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFSGLEKIISARGRTTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPEFVGRLPVVATLEDLDEASLKKILTDPKNALVKQYQRLFEMENIELTFADEALGAVARKAIERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVVEGTARPLYIYADRADRASETSASA",
    "output": "ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFAGKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNNVITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYEAALAVLKA",
    "output": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MHRKVILLLTVSLLLRIGFFSYGIFQDSHFDVKYTDIDYFVFHDAAGYVNNGQSPYLRDTYRYTPLLSFLLLPNYYLKWIHMGKVFFVLFDLITGVMIIKLLQGSCQLTKQLILASIWLLNPIVITISTRGNAESVLCFLIICALYFLKRDRLLISGLFYGLSIHFKIYPIIYALPIGIYLLLSSHNRNCIWRLFMIGISTLIGITAPTYFMYKLYGSEFIEHSYMYHLTRTDHRHNFSIWNLVLLLESAGIHLSQSIELSKLAFVPQLTLCAVLPYLLWKSQTFENLMNVLFVQTYAFVTFNKVCTSQYFIWYLVLSPFYFANTTITWRKGVVCIFLWILSQAVWLSQAYLLEFKGQNVFFPNLFFGNIVFFLINVYLLGVFITDIKSRTSFQDNQHKKNI",
    "output": "Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKYQQLENLESGWKWAYLVKKHREGEAITRHIENSAAQDAVEQLMKLENEPVKVQEWIDAHMNVNLATRMKQTIRARRKRHFNAEHQHTRKKSIDLEFLVWQRLAVLARRRGNTLSDTVVQLIEDAERKEKYASQMSSLKQDLKDILDKEV",
    "output": "Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNKILLKRQILYNLPKYFKNNIPYTITINKSNQFINNNCKNNNNNFRKLNFTTTTTTTTTAPITNNKPKSNMLYSPKDRSYEEAVNALLTLQSNQTVIISWTKERRDNKEESAKFLMEEMRNYCKTLSIDLERESIIHVAGTKGKGSTCAITESIIREQGFSTGLFTSPHLISPRERIRINGEMISKEMFSQYFWNCWDLLIKDYQTQLPNFFRYLTLMALKIFQDEAIQCTILEVGIGGRMDSTNVFPKPMVTGISALGYDHQNLLGNTLAEIALEKAGIMKVGIPIFTVSSQLPEAINVLIDHSNKVKSPLSIVPSIDQYTISSGGGNNNNNKIESIGLKGTHQLENASLAIALANCWFKKQTFKDVNEIFNSENHKQYNYETNNYNVTQFTPLLKSIELGLKNCEWAGRAQHFTNPSHFPNMDFYLDGAHTVESSIVMLNWWKSIVNTTTTTTTTTTTTTTNNNDDDTIHILIFNSTGGRNPTSFLTPIIQSIDNKEIPIFNKSIIPNIIIEKPIDKKYYINEIIQSNQSSTATTTPIPDNAAVKQTTEIKESSTWEDFVVECYDKLSKKSHPCITADSIESSIEIAKELSENGTKNVKVLITGSLYLVGGVLKVLLKEKSFN",
    "output": "Conversion of folates to polyglutamate derivatives."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRVVVAITGASGTIYGIKLYETLRDLGHEVILLASKTGIKVAKYETGIEVKPDFSEDELFAPIASGSYPFDAMVIAPCSMKTLSAIANGFSNNLITRAADVALKERRKLVLLIRETPLNLIHIQNMLKITQAGGIIMPASPAFYHKPGTIDDMIKFIIGKILDVLGINHNLYKRWGMDYND",
    "output": "Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLRFVIGRAGSGKSTLCLHEVQEELKQRPRGETILYLVPEQMTFQTQQALIGSEDVRGSIRAQVFSFSRLAWKVLQEVGGASRLHIDEAGVHMLLRKIVESRKDGLSVFQKAAEQNGFFEHLGSMIAEFKRYNVTPSNVYEMWQQLDAHSSSAEQKLLANKVYDLQLLYDDFERALIGKYLDSEDYLQLLVEKLPQSEYVKGAEVYIDGFHSFSPQELEIVRQLMICGARVTITLTIDEKTLAQPVNELDLFYETTLTYEKIKQVAREEKIEIEKTIPLMEQPRFHSPALAHLEMHYEARPNEKFHGEASVTIHTAANLRAEVEGVAREIRRLVAEENYRYRDIAVLLRNGESYYDVMRTLFTDYNIPHFIDEKRPMSHHPLVECIRSALEIISGNWRYDAVFRCVKTELLYPLDVRKETMREEMDEFENYCLAYGVQGKRWTSEDPWMYRRYRSLDDTNGMITDSEREMEEKINRLRDVVRTPVIRMQKRLKRAGTVMQMCEAVYLFLEELDVPKKLEALRIRAEENGDFLFATDHEQVWEEVMSLLDTFVEMLGEEKMSLSMFTDVMSTGLEALQFANIPPSLDQVLIANIDRSRLSNVKATFVIGVNEGVIPAAPMDEGMLSDEERDVLSAAGIELAPTTRQTLLEEQFVMYQMVTRATEKLYISCPLADEEGKTLLASSFIKKIKRMFPDVKDTFITNDVNDLSRLEQISYVATPEVTLSYVMQQLQTWKRYGFEGNLDFWWDVYNFYVTSDEWKQKSSRVLSSLFYRNRAQKLSTAVSRDLYGDKIKGSVSRMELFNRCAYAHFAQHGLSLRERDIFKLDAPDIGELFHAALKRIADRLLRENRTWADLSIKECEHLSAVVIEEIAPLLQRQILLSSNRHFYLKQKLQQIIFRTSIILREHAKSSGFVPVDLEVPFGMGGTGSLPPMEFSLPNGVKMEVVGRIDRVDKAEDENGTFLRIIDYKSSSKALDLTEVYYGLALQMLTYLDVVTSNAQTWMKKGGTASPAGVLYFHIHNPIVEVKGDASEAEIEKEILKKFKMKGLVLGDADVVRLMDNKLSTGSSDIISAGLKKDGSFSARSSIASEQEFNVLQKYVHHTFENIGKDITEGVIDIAPYKKGNKAACTFCNFKSVCQFDESLEDNQFRTLKDMKDSEAMEKIREEVGGE",
    "output": "The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "METRYNLKSPAVKRLMKEAAELKDPTDHYHAQPLEDNLFEWHFTVRGPPDSDFDGGVYHGRIVLPPEYPMKPPSIILLTANGRFEVGKKICLSISGHHPETWQPSWSIRTALLAIIGFMPTKGEGAIGSLDYTPEERRALAKKSQDFCCEGCGSAMKDVLLPLKSGSGSSQADQEAKELARQISFKAEVNSSGKTIAESDLNQCFSLNDSQDDLPTTFQGATASTSYGAQNPSGAPLPQPTQPAPKNTSMSPRQRRAQQQSQRRPSTSPDVLQGQPPRAHHTEHGGSAMLIIILTLALAALIFRRIYLANEYIFDFEL",
    "output": "Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) and is essential for cells to recover from ER stress. Plays a role in MAPKAPK2-dependent translational control of TNF-alpha synthesis. Acts also as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1 through interaction with the E3 ubiquitin-protein ligase RNF26."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR",
    "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLSPVSRDASDALQGRKCLRPRSRRLPLPAAVRAHGPMAELTDSARGCVVFEDVFVYFSREEWELLDDAQRLLYHDVMLENFALLASLGIAFSRSRAVMKLERGEEPWVYDQVDMTSATEREAQRGLRPGCWHGVEDEEVSSEQSIFVAGVSEVRTLMAELESHPCDICGPILKDTLHLAKYHGGKARQKPYLCGACGKQFWFSTDFDQHQNQPNGGKLFPRKEGRDSVKSCRVHVPEKTLTCGKGRRDFSATSGLLQHQASLSSMKPHKSTKLVSGFLMGQRYHRCGECGKAFTRKDTLARHQRIHTGERPYECNECGKFFSQSYDLFKHQTVHTGERPYECSECGKFFRQISGLIEHRRVHTGERLYQCGKCGKFFSSKSNLIRHQEVHTGARPYVCSECGKEFSRKHTLVLHQRTHTGERPYECSECGKAFSQSSHLNVHWRIHSSDYECSRCGKAFSCISKLIQHQKVHSGEKPYECSKCGKAFTQRPNLIRHWKVHTGERPYVCSECGREFIRKQTLVLHQRVHAGEKL",
    "output": "May be involved in transcriptional regulation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRNPNIFLALYVTGSWIWRQRMPMAQCLKSCVCSDYEPLVKDAVQLPVVDEGRVTAAVNVVKLFLPDCLSVDDVLKSRDELKKLAQARNISKILAKSATAIHIARGIKCPKGTENVLRQTLVDNCTVFKSMYSVLAYLYLSPGADTDGMIDQVVAQTADRTIMLGDMTVLSHAMRVDGVDIPHSSQDLAKMGLSAADSDTLDPIQLVGVMEPPSPPPHTADAREDAPHVSPPERRPQSSATLTSLDAKSRRGLAGQVPAS",
    "output": "Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKLNNLPSEFQEALPILEKIKAAGFEAYFVGGSVRDAILGRPIHDVDIATSSYPQETKQIFSRTIDVGIEHGTVLVLEGKKEYEITTFRTEEEYVDFRRPSQVSFVRSLEEDLKRRDFTVNAFALDEEAQIVDLFDGMTDLENRTLRAVGIPAERFNEDALRIMRGFRFAATLDFEIEPTTFEAMVQTAPLLEKISVERSFIEFDKLLMADFWRKGLRAMIDSKAYNFLPDLAGKSDELEAMLTSLTEEFRFSTSEQAWALLFVCLGIDNIKSFLKKWKTSNDFQRSVVKLVEIYQLRQAGPVTKQICFKYGKEFLYLVEELHQAQGFVTDFAAIDKIDQALTIHDKHEIVVNGGHLMKAFDLKPGPVLGELLKEVEFQIVEGQLENEEQAIMTFVKGILENE",
    "output": "Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAVNQEKEKAIELAMSAVERQFGKGSIMRLGNDEPMMRDVQAIPTGSISLDIALGVGGVPKGRIIEIFGPESSGKTTLCLHIVAEAQKRGGICGYVDAEHALDVGYARKLGVRTDDLLLSQPDTGEQALEIAEMLVRSGAIDVLVVDSVAALVPKAELEGEMGDAHMGVQARLMSQALRKLTGTIAKSQTCVIFINQIRMKIGVMFGNPETTTGGNALKFYASQRLDIRRIGAIKNGDNVVGSRTRVKVVKNKVAPPFKEVEFDIMYGTGISREGDLIDLASNENIVEKSGSWFSFNGERIGQGRENVKEYLREHPEIAKDIEGRVLEKYGIGKSGAPSPRRRTSPRRPKVAARSAAV",
    "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKRLVLFAAVVIALVALTTAEGEASRQLQCERELQESSLEACRQVVDQQLAGRLPWSTGLQMRCCQQLRDVSAKCRSVAVSQVARQYEQTVVPPKGGSFYPGETTPLQQLQQGIFWGTSSQTVQGYYPSVTSPRQGSYYPGQASPQQPGQGQQPGKWQEPGQGQQWYYPTSLQQPGQGQQIGKGKQGYYPTSLQQPGQGQQIGQGQQGYYPTSPQHTGQRQQPVQGQQIGQGQQPEQGQQPGQWQQGYYPTSPQQLGQGQQPGQWQQSGQGQQGHYPTSLQQPGQGQQGHYLASQQQPAQGQQGHYPASQQQPGQGQQGHYPASQQQPGQGQQGHYPASQQEPGQGQQGQIPASQQQPGQGQQGHYPASLQQPGQQGHYPTSLQQLGQGQQIGQPGQKQQPGQGQQTGQGQQPEQEQQPGQGQQGYYPTSLQQPGQGQQQGQGQQGYYPTSLQQPGQGQQGHYPASLQQPGQGQGQPGQRQQPGQGQHPEQGQQPGQGQQGYYPTSPQQPGQGQQLGQGQQGYYPTSPQQPGQGQQPGQGQQGHCPMSPQQTGQAQQLGQGQQIGQVQQPGQGQQGYYPTSLQQPGQGQQSGQGQQSGQGHQPGQGQQSGQEKQGYDSPYHVSAEQQAASPMVAKAQQPATQLPTVCRMEGGDALSASQ",
    "output": "Glutenins are high-molecular weight seed storage proteins of wheat endosperm. Thought to be responsible for the visco-elastic property of wheat dough."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLSAKGVSLGLGLGLGAWGPVLLGVVGVAGALALYGYYKNRNAEPAAAEAV",
    "output": "Might be involved in magnetite crystal growth."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSLMDPLANALNHVSNCEGVGKNVAYLKPASKLIGRVLKVMQDQGYIGNFEYIEDGKAGVYKVDLIGQINKCGAVKPRYAVKYQEFEKFEKRYLPAKGFGLLIVSTPKGLMTHDEARTAGVGGRLISYVY",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKGLFVTIEGPEGSGKTTLIKSLLPYFEQKAQKVMATREPGGIAISEDIRTILHKQEYTMMEARTEALLYAAARRQHLVEKVMPALNEDYLVLCDRFIDSSLAYQGYARGLGMDKIFEINRFATEDCMPSLTIYLDIEPEVGLARIEKDAGREVNRLDMEDISFHKRVREGYLQVVERFSDRIVLVNADQPMEKLIEEVVQIIEDKLL",
    "output": "Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKRLDLNDVNIYYGDFHAVQDVNLHIPPKAVTAFIGPSGCGKSTVLRTLNRMHEVIPGAYVKGEILLDGEDIYGPKIDPVAVRNTIGMVFQKANPFPTMSIEENVVAGLKLSGEKNKKKLREVAERALRGANLWDEVKDRLDKPGGGLSGGQQQRLCIARAIAVEPEVLLMDEPCSALDPISTLAVEDLIHELKEDFTIVIVTHNMQQAARVSDQTAFYSLEATGKPGQLVEVGPTKQIFENPTKKETEDYISGRFG",
    "output": "Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKNLGNMMKQAQQMQARMQEMQSKLAEVEVNGVSAGGMVSILLNGKGELKQIKLDKSVVDPEDVEVLEDLIVAAFNDAKNKVEAHMAEETAKLMGGLKLPPGFKLPF",
    "output": "Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAAESGKVDPMKQFSIEPMLGSEGWEIAGYNIAFTNSAAWMALTTVLLAVFVWGGMKGQLVPGRWQMMVESFTSFIDDMLEVNIGKAGRKYVPYVFSLFMFILFGNLLGLLPLGVLGIHPFTFTSHFTITGVLAIISFSIVLIVGFWKHGFHFFSLFVPSGTPLPMIPIIFPIELISFLVRPFSLALRLFVAMMAGHVLLKVLSSFVIDGINAGAGFGLLVGAPSFILMIGISALEILVAGIQAYVFALLTSLYINDAENLH",
    "output": "Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFINRWLFSTNHKDIGTLYMIFGAWAGMVGTGLSILIRAELGQPGSLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAITQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTIGGLTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFTGYTLNDTWAKIHFTIMFVGVNMTFFPQHFLGLAGMPRRYSDYPDAYTTWNTISSMGSFISLTAVILMVYMIWEALASKRLVKSVPLTTTNLEWMHGCPPPFHTFEEPVFIKSPQL",
    "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGESERSEAFGIPRDSPLSSGDAAELEQLRREAAVLREQLENAVGSHAPTRSARDIHQLEARIDSLAARNSKLMETLKEARQQLLALREEVDRLGQPPSGYGVLLATHDDDTVDVFTSGRKMRLTCSPNIDAASLKKGQTVRLNEALTVVEAGTFEAVGEISTLREILADGHRALVVGHADEERVVWLADPLIAEDLPDGLPEALNDDTRPRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVSYADIGGLSRQIEQIRDAVELPFLHKELYREYSLRPPKGVLLYGPPGCGKTLIAKAVANSLAKKMAEVRGDDAHEAKSYFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGTGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAQDIYSKYLTEFLPVHADDLAEFDGDRSACIKAMIEKVVDRMYAEIDDNRFLEVTYANGDKEVMYFKDFNSGAMIQNVVDRAKKNAIKSVLETGQPGLRIQHLLDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKSSSASRAIDTESNLGQYL",
    "output": "ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIWNNDDTEHSTGGLYRWTMDALFGRQISPSRKFKEVSQDDTNYNMKSHKDKQWDGHGFQPRTRSSSASFDRSFLQRYELLQDEEEQDIMRPVRSPARPYLSAGHAAGQDAALANDESTDTFSNKRQRFKGKFSGPKYHDESLKFRAPAKNDPFISKLFQRESPEHPSNLPGKFPSPFKQALGLPAGVQVQLDPEEQIPQKMFTDEYLQLLAELDQNGQKLKQLQQGLHQKQQDHILQETSYREKYHVMRQELITELKQSKKLYDNYYRLYEKHKKMRALDTDASRLRQRISDLEAQVVDASIEKAEEVRKLNETIFQLEFREQETQSKHERERIRYQSRIAELESIVESRLSISNGVQNPPLRERIKPVNSSARI",
    "output": "Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication. Connects the central plaque of the SPB with the half-bridge. Required for proper localization of CDC5 at the SPB and for proper M-phase progression (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDVLINKLASCNFSRTRNQVGKPCIINCVPGAGKSTLIRELLNSDSRFRAYTFGEADPKNLSGRRILPASELQNAPQGALIIIDEYTEGSWEPGKICAAFGDPIQSRGPGIVADFVCNKTKRFGSSTCELLNGFGFEIHSEKEDICLVRDFFEVEPEGTVIAFESEVKDILARHFVEFEDICSIRGKTFEEVTFFTASNSIPEHLRADFFQCLTRHKNKLTIACPDATFAPS",
    "output": "Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Increases plasmodesma size exclusion limit. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSQVNTSQGPVAQGRQRRLSSLSEFNDPFSNAEVYYGPPTDPRKQKQAKPAKINRTRTMSVFDNVSPFKKTGFGKLQQTRRGSEDDTYSSSQGNRRFFIEDVDKTLNELLAAEDTDKNYQITIEDTGPKVLKVGTANSYGYKHINIRGTYMLSNLLQELTIAKSFGRHQIFLDEARINENPVNRLSRLINTQFWNSLTRRVDLNNVGEIAKDTKIDTPGAKNPRIYVPYDCPEQYEFYVQASQMHPSLKLEVEYLPKKITAEYVKSVNDTPGLLALAMEEHFNPSTGEKTLIGYPYAVPGGRFNELYGWDSYMMALGLLEANKTDVARGMVEHFIFEINHYGKILNANRSYYLCRSQPPFLTEMALVVFKKLGGRSNPDAVDLLKRAFQASIKEYKTVWTASPRLDPETGLSRYHPNGLGIPPETESDHFDTVLLPYASKHGVTLDEFKQLYNDGKIKEPKLDEFFLHDRGVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEIDIADFIKEFCDDKYEDPLDHSITTSAMWKEMAKIRQEKITKYMWDDESGFFFDYNTKIKHRTSYESATTFWALWAGLATKEQAQKMVEKALPKLEMLGGLAACTERSRGPISISRPIRQWDYPFGWAPHQILAWEGLRSYGYLTVTNRLAYRWLFMMTKAFVDYNGIVVEKYDVTRGTDPHRVEAEYGNQGADFKGAATEGFGWVNASYILGLKYMNSHARRALGACIPPISFFSSLRPQERNLYGL",
    "output": "Hydrolyzes intracellular trehalose to glucose  (Probable). The disaccharide trehalose serves as a storage carbohydrate that is mobilized during nutrient stress (Probable). Regulates the level of trehalose as a protectant for cell integrity during heat stress ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKIRIGHGFDVHKFGEPRPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDAAYKGADSRVLLRHCYALAKAKGFELGNLDVTIIAQAPKMAPHIEDMRQVLAADLNADVADINVKATTTEKLGFTGRKEGIAVEAVVLLSRQ",
    "output": "Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEEKQPAFMR",
    "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAATQAQENINQSPWAERINIYPADIQQWITQQTARFDLIISNPPYYQQGVECATPQREQARYTTTLDHQSLLTCAAECITEEGFFCVVLPEQIGNGFTELALRMGWHLRLRTDVAENETRQPHRVLLAFSPQAGECYSDRLVIRGPDQSYSEAYTALTQAFYLFM",
    "output": "Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQPWYHKLGRQGRQLAEQWQTDAEPWGVATPTPLDYLFDELTAPKPSTTPDKVLSYLAYYYPKLKNENNVELLTLCFLRCPLFFNDAQLVSFSDNYRVIECFKYIMDKKFQISQPTLPFYRFYNALFGALAKVVADSACAWKVVPVAVGCLLSVDSRNDYDRYPEHFQLIATVDAKLVDMAAHTLERSMDGPLSNDLLCLNVVALSCVQDKLVDSQLLRILRVRSDILKILTELTFNSPYGLDNGRLLTKSNANTPIVVRHLNRISFLFTKLTSIHPKIVLLADDLDLILNRIQTFSESVLSIPNPSETQWSTLRVVLFAQVMMFEGIMARFFQINNHSLNSTVLPTLCRKILTTLFNFNFVVDRIGTGGFESYNFVYASCLSTLTSYDIPTAETLIKCWTSSVAFKKVDNSATERGKLLFDLQFIENVVNLVSDSLKFEFIIPIVQDLIGNAQDQAVLESAHSVMLKYFTSVDTYNEAQLVDYTNNVKHVGAQLIDYLTLSLDQFPARLSLSQVGIIVETLAKITFPDTAVHECDPELYRELLLLVYNRCLVATSEELPNVQAPPKTRHGAFTSLLIRILPLIPFDEYQSWLERTLSLAFRTVGDERTYLLDLLWDSILGTNRHYPQKGYVGIQWWYEHVNESQEKAKL",
    "output": "Essential for peroxisome biogenesis. May play a role in triggering the protein import competence of individual peroxisomes. It may interact with PEX10."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMVPEELQDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAKTRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL",
    "output": "Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSSSPSRNPTNAEAPPPPPTSTDAVAEGSSKKVRKPYTITKSRESWTEEEHDKFLEALQLFDRDWKKIEDFVGSKTVIQIRSHAQKYFLKVQKNGTLAHVPPPRPKRKAAHPYPQKASKNAQMPLQVSTSFTTTRNGDMPGYASWDDASMLLNRVISPQHELATLRGAEADIGSKGLLNVSSPSTSGMGSSSRTVSGSEIVRKAKQPPVLHGVPDFAEVYNFIGSVFDPETRGHVEKLKEMDPINFETVLLLMRNLTVNLSNPDLESTRKVLLSYDNVTTELPSVVSLVKNSTSDKSA",
    "output": "Transcriptional activator of evening element (EE)-containing clock-controlled genes. Forms a negative feedback loop with APRR5. Regulates the pattern of histone H3 acetylation of the TOC1 promoter."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRTVKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSVHSILFSSEHVTEGHPDKLCDQVSDAVLDACLAGDPFSKVACESCAKTGMVMVFGEITTKAVLDYQKIVRNTIKDIGFDSADKGLDYESCNVLVAIEQQSPDICQGLGNFDSEDLGAGDQGMMFGYATDETETLMPLTYELARGLAKKYSELRRSGSLEWARPDAKTQVTVEYDYDTREGKQVLTPKRVAVVLISAQHDEHVTNDKISVDLMEKVIKAVIPANMLDAETKYWLNPSGRFVRGGPHGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPSKVDRSAAYAARWIAKSIVAGGLARRCLVQLAYAIGVAEPLSMHVETYGTGKYDDAKLLEIVKQNFKLRPYDIIQELNLRRPIYYDTSRFGHFGRKDELGTGGFTWEVPKKMVE",
    "output": "Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDQYPDLNESRAFDQIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDEELIELVEMEVRELLAAQDFDEDAPVVKVSALKALEGDEKWVKSVQELMAAVDESIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGIRPTVTKTTVTGVEMFRKLLDQGQAGDNVGLLVRGIKREDVERGQVVVKPGTTTPHTEFEGSVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNTDIAVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAELTTLARPYAKAAFEHAQAHQQLANWSAMLGLAAAVSQDDTMQRLLKAPRLTSAEKAATFIDVCGDKFNAQAQNFIHVAAENDRLLLLPEIAALFDLYKAEQEKSVDVEVTSAFALNQEQQDKLAKVLSARLGQEVRLHASEDASLIGGVVIRAGDLVIDGSVRGKIAKLAEALKS",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSPIAVTSQTPATEVPSVKEIPQVITKSSPVENLILTTYPEDSSPIPLQWGAPSTDSRGPIIATRYKEGLAKHNAIGAHSGSYCVYHALAVGTKQLDPEHVADYTNSQPAFAVPEQKTWYNDEDIVAMDPFGHLTPYLFDEVSTKENVEIRPTIAVTKATMQLFEMKDAVEKGRLEVDGEVVINKNGDLNVSKVAVEPVWYLPGVAKRFGVTEEELRKALFEDTNGMYPELVTRPDIKVFLPPIGGLTVYIFGNPDFVSDPSKKLALRVHDECNGSDVFGSDICTCRPYLMFGIEEAVKEAQNGGSGVVVYFRKEGRALGEVTKYLVYNARKRGGDTADEYFHRTECIAGVRDMRFQQLMPDVLKWLGISKIDRMLSMSNMKHDAIVDQGIPIIERIPIPDELVPPDSRVEIDAKINSGYFTNGKVMDKNELKSVQGRTWNDVK",
    "output": "Involved in uracil catabolism."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNKGRVTQIMGPVVDVKFDGGKLPEIYNALTVKQSNENGTSINLTFEVALHLGDDTVRTVAMSSTDGLVRGTEVEDTGKAISVPVGDATLGRVFNVLGDAIDLDGEVPADVRRDPIHRQAPAFEELSTKVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYHEMSDSGVIKKTAMVFGQMNEPPGARQRVALTGLTMAEHFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNKGSITSIQAVYVPADDYTDPAPATTFAHLDATTNLERRLTQMGIYPAVDPLASTSRALSPEIVGEEHYEVARQVQQTLQRYKELQDIIAILGMDELSEEDKLVVHRARRIQFFLSQNFHVAEQFTGQKGSYVPVKETVRGFKEILEGKYDDLPEDAFRLVGGIEEVIENAKKMMA",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MERSLALANMTRVQQFILLGLSTRLDIRDALFAVFLTLYLLTLLENTLIIYLICSHKELHKPMYFFLGNLSCLEMCYVSVTMPTLLMGLWNGLYHIPFIACMTQLFFFIVLVGTECILLASMAYDRYVAICRPLHYPVLMRPQVCLGLAMISWLGGLLVSMIKTTCIATLSYCGPNVLNHFFCDVSPLLNLSCTHVALTELVDFISAIVILWGCFLTTMASYVAIGRAVLRMPSTTARYKAFSTCASHLVVVGIFYSVTIFIYARPKRIEAMDLNKVLSVIYTVVTPMCNPVIYCLRNKEVQVALHRTMHWS",
    "output": "Odorant receptor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSYQEQQCKQVCQPPLVCPPRSAQSPVLCQSAPSLVLLQSAQSPIHCQSALSHAHLSHASRNALLCNLLHHASKSAHPRANKGFSSLQNQKKRTESILHKSIATPPSSI",
    "output": "Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGVSLRHLSPSSFWVSRRPRVSSSILSFLVPRRRILCTRKVAIIKGNAGYSTATDCGGSHGFHHSGHQRSSSVEFSGEWKLNLGSKTARMVPPTVKQAGAVSAWREEVNNKLRGRNREYANNQDDAFGNGSYILKGFVPKIDDVHSYGNGQNFDYNLKPGTDITTLGRELNGFMQTNSIRGSVVALPSKDIEVGETTDVTLKPLNSDTTLDNASYKKTATISKVEKCTNLSQVRANLKKIYNRVRVVDNVSSAKETVALLMNQYRNLVHACDTEVSRIDVKTETPVDHGEMICFSIYCGSEADFGDGKSCIWVDVLGENGRDILAEFKPFFEDSSIKKVWHNYSFDNHIIRNYGIKLSGFHGDTMHMARLWDSSRRISGGYSLEALTSDPKVLGGTETKEEAELFGKISMKKIFGKGKLKKDGSEGKLVIIPPVKELQMEDREAWISYSALDSISTLKLYESMKKQLQAKKWFLDGKLISKKNMFDFYQEYWQPFGELLAKMESEGMLVDRDYLAQIEIVAKAEQEIAVSRFRNWASKHCPDAKHMNVGSDTQLRQLFFGGISNSCNDEDLPYEKLFKVPNVDKVIEEGKKRATKFRNIKLHRISDRPLPTEKFTASGWPSVSGDTLKALAGKVSAEYDYMEGVLDTCLEENIGDDDCISLPDEVVETQHVNTSVESDTSAYGTAFDAFGGGESGKEACHAIAALCEVCSIDSLISNFILPLQGSNVSGKDGRVHCSLNINTETGRLSARRPNLQNQPALEKDRYKIRQAFIASPGNSLIVADYGQLELRILAHLASCESMKEAFIAGGDFHSRTAMNMYPHIREAVENGEVLLEWHPQPGQEKPPVPLLKDAFASERRKAKMLNFSIAYGKTAIGLSRDWKVSREEAQDTVNLWYNDRQEVRKWQELRKKEAIQKGYVLTLLGRARKFPEYRSRAQKNHIERAAINTPVQGSAADVAMCAMLEISNNQRLKELGWKLLLQVHDEVILEGPSESAENAKDIVVNCMSEPFNGKNILSVDLSVDAKCAQNWYAGK",
    "output": "In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity (By similarity). Required for DNA replication and accumulation in plastids and mitochondria."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTYALLKKIDAPADLRKLDRRELRTLADELRAYVLESVSQTGGHLSSNLGTVELTIALHYVFHTPDDRVVWDVGHQSYPHKILTGRRERMNTLRQFGGISGFPRRSESQYDTFGTAHSSTSISAALGMALGARTLGEQRVSIAVIGDGAMTAGMAFEALNNAGVYKDLPLVVVLNDNDMSISPPVGALNKHLARLLSGQFYAATKKGIEKVLSVAPPVLEFAKRFEEHAKGMMVPATLFEEFGFNYIGPIDGHDLDSLVPTLQNIRKRALEGAGPQFLHVVTKKGQGYKLAEADPILYHGPGKFNPAEGIRPAAKPARKTYTQVFGEWLCDMAAADKRLIGITPAMREGSGMVEFEKRFPERYYDVGIAEQHAVTFAGGMACEGLKPIVAIYSTFLQRGYDQLIHDVALQNLPVVFALDRAGLVGADGATHAGAYDIAYLRCIPNMMVMTPSDENECRQLLTTAFHQNCPTAVRYPRGAGQGVATEAVLKDVPVGKGVMRRTGGARSGQRVAFLGFGSMVHPALGAAQALDASVADMRFVKPLDVELVKRLAEEHNYLVTVEEGSVMGGAGSAVLEALAEAGIDIPVLVLGLPDRFIDHGDPALLLSQCGLDAAGIERSVRERFGIGQAPVAVASRVA",
    "output": "Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPVPGDDMGETPLTRTPIPMPAYFSQAEQSFSLKKRGRSLCYTLPPRPPVKSALPVSRIFPNKQRSWSQPRPQSVSFRSPQNKTPASKLYDQSKGDTFFKQCFKSICKLGRGSFGEVYKVQSLEDGCFYAVKRSVSPFRGESDRQRKLQEVRKHERVGEHPNCLRFVRAWEEKRMLYLQTELCAGSLQQHSEEFAGSLPPRRVWNITCDLLHGLKHLHDRNLLHLDIKPANVFISFSGVCKLGDFGLMVELDGTEGSGEAQEGDPRYMAPELLDGIFSKAADVFSLGMSLLEVACNMELPKGGDGWQQLRQGHLPTEFTSDLPPDFLKVLSAMLEPDYRRRATVDWLLSLPAIRNAERWRMVTLAQERTLGKIIAVYQFIVWLLSFVFQWLNRPVIGFLHYCGLRALPRSPPCSPFPNHLGESSFSSDWDDESLGDDVFEVPPSPLATHRNLTYHGQELIGRHSPDLLSRPSLGSTSTPRNLSPEFSMRKRSALPLTPNVSRISQDSTGKSRSPSTSHSSSGFVDAEVQRTLFLPRNLLGMFDDATEQ",
    "output": "Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTAIVDVHARQIIDSRGNPTVEVDITLEDGSFGRAAVPSGASTGAYEAVEKRDGDKSRWLGKGVQDAVDAVNDEIADAIIGMEAEDQSEIDARLIELDGTPNKGRLGANAILGASLSVARAAAEARALPLYRYVGGVSAQVLPVPMMNIINGGAHADNPIDFQEFMIMPVGAPTLFDAVRAGSEIFHTLKKALHDKGLATAVGDEGGFAPNLASAPDALDFIMQSIEKAGYKPGDDVVLALDCAATEFFKDGVYDFHGEGVKRSPAEMADYLADLCARYPIVSVEDGMGEDDFEGWKILTDKIGHKVQLVGDDLFVTNPKRLAQGIKDGLANSLLVKVNQIGTLSETLEAVNMAQRAGYTAVMSHRSGETEDSTIADLAVATNCGQIKTGSLARSDRLAKYNQLIRIEEELGPVAVYAGRSAIKALG",
    "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEKQVEIPEVELNSGHKMPIVGYGTCVPEPMPPLEELTAIFLDAIKVGYRHFDTASSYGTEEALGKAIAEAINSGLVKSREEFFISCKLWIEDADHDLILPALNQSLQILGVDYLDLYMIHMPVRVRKGAPMFNYSKEDFLPFDIQGTWKAMEECSKQGLAKSIGVSNYSVEKLTKLLETSTIPPAVNQVEMNVAWQQRKLLPFCKEKNIHITSWSPLLSYGVAWGSNAVMENPVLQQIAASKGKTVAQVALRWIYEQGASLITRTSNKDRMFENVQIFDWELSKEELDQIHEIPQRRGTLGEEFMHPEGPIKSPEELWDGDL",
    "output": "Component of iboga and aspidosperma monoterpenoid indole alkaloids (MIAs, e.g. tabersonine and catharanthine) biosynthesis pathway from 19E-geissoschizine. Catalyzes the second oxidation step of the unstable intermediate product resulting from the reaction triggered by the geissoschizine oxidase (GO) in the stemmadenine biosynthesis process from 19E-geissoschizine."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMETQLYIGIMSGTSMDGADAVLIRMDGGKWLGAEGHAFTPYPGRLRRQLLDLQDTGADELHRSRILSQELSRLYAQTAAELLCSQNLAPSDITALGCHGQTVRHAPEHGYSIQLADLPLLAERTRIFTVGDFRSRDLAAGGQGAPLVPAFHEALFRDNRETRAVLNIGGIANISVLPPDAPAFGFDTGPGNMLMDAWTQAHWQLPYDKNGAKAAQGNILPQLLDRLLAHPYFAQPHPKSTGRELFALNWLETYLDGGENRYDVLRTLSRFTAQTVCDAVSHAAADARQMYICGGGIRNPVLMADLAECFGTRVSLHSTADLNLDPQWVEAAAFAWLAACWINRIPGSPHKATGASKPCILGAGYYY",
    "output": "Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAPTTPATHDPALSHGAPPTQGSQAPANAAPNLTPADISGMQLNGLDQSQIMNLLRSLPGMFTGAKIPDQGQGNPKEDAAQTLSNLAQASSPFGGQHLPIHYQTGAAGGLPGINDPGPSTHPRGPPNLGQLSAVAMQAAPATIQHQDQQQSGRQEDGEQAGNTSIDSPSAKDGENGTGEFNQTSTSTPSGGRRGGRSATMGSDEWSRQRKDNHKEVERRRRGNINEGINELGRIVPSGSGEKAKGAILSRAVQYIHHLKENEARNIEKWTLEKLLMDQAMGDLQAQLEEIKRLWEEERMARTRLEAELEVLRNMNGVSTAGAGSGAAKDESAAGTKRRSTDGADAAGTNVEGGNNDNAEGERDGKRQRTE",
    "output": "Transcription factor that may regulate the expression of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHKTDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGFSQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGAGFYFYDAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLSSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQTYRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAHYITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV",
    "output": "Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPINLYSKAVFLKSAARVNQLPEDSGYEVAFAGRSNAGKSSALNCLTNNKNLARTSKTPGRTQLINLFSLDEQRRLVDLPGYGYAKVAMEVKLEWQKNLAHYLEARQCLRGLILLMDVRHPLKDLDQILVNWALHRELPVHILLTKADKLSRSEVKNAVLKVRQYYELAEHLVSVQAFSSVKKDGVEELISVLDRWYEWN",
    "output": "Necessary for normal cell division and for the maintenance of normal septation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNEQSPALRNFTINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLIETKTYLQAMPYFDRLDYVAPMNQEHAFCLAAERLLGIEVPRRGQLIRVLYSEIGRLLSHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERASGSRMHANYFRIGGVHQDLPPKLVDDIDAFCDPFLKVVDDLDQLLTGNRIFKQRNVDIGVVTLKQAWEWGFSGVMVRGSGAAWDLRKSQPYDVYAEMEFDIPIGKNGDCYDRYLIRMEEMRQSVRIMKQCIAKLRAPDGQGPVLITDNKIAPPRRGEMKRSMEALIHHFKLYTEGVHVPAGEIYAAVEAPKGEFGVYLVADGTNKPYKCKIRAPGFAHLQAMDFLCRGHLLADVSAILGSLDIVFGEVDR",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKDIATPNRTKDIVEKYGFSFKKSLGQNFLIDTNVLNRIVDYAEIGPKGGAIEIGPGIGALTEQLAKRAKKVVAFEIDQRLLPILDETLAPYDNVTIINKDVLKANVHEVFQEQFEEGQDVMVVANLPYYVTTPILFKLLEEKLPVRGFVVMMQKEVGDRLAAKPGTKDYGSLSIAIQYYTEVETVMTVPRTVFVPQPNVDSSVIRLLKRPKPIVEVIDEKFFFEVVRASFAQRRKTLMNNLSNNLNDFPKDKELLERILTEIGIDPKRRGETLSIEEFAMLSNALVPHKMK",
    "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIWLTLVFASLLSVAGQLCQKQATCFAAVNKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSLRHWCGLAFIIGGIVILGSTV",
    "output": "Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKTYTAKPETVQRDWFVVDAAGQTLGRLATEIARRLRGKHKPEYTPHVDTGDYIVVINAEQVRVTGAKTTDKMYYHHSGFPGGIKSINFEKLIAKAPERVIETAVKGMLPKNPLGRDMYRKLKVYKGASHPHTAQQPQELKI",
    "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKDILILGIETSCDETSASVVKNGRQVLSNVISSQVALHQKYGGVVPEIASRKHVELIMPVIHQSLEEAGIKIEQVDAIGVTYGPGLVGALLVGLSAAKALAFALDKPLIGVHHIEGHIAANYIEHSLLEPPFVCLVASGGHSHIVYVQDYDKFEIMGKTRDDAAGEAFDKVARAVGLGYPGGPIIDKTAKLGNSKAIDFPRVHFGDQSLDFSFSGLKTAVLNYINSMEQKGEKYSVEDVCASFQAAVVDVLTDNLISAARIKGVKKVALAGGVAANSLLRSELVEKAKGLGLEVFYPKPVLCTDNAAMIACAAYYEFLRGHTSDVYLNAIPGLKLGER",
    "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLARRIIAALDIKDGRVVKGIKFKNIRDAGDPIELAKRYESEGIDEIVFLDITASYEKRKILLDLVERVAEEIYVPFTVGGGIRTVEEAREIIRRGADKIFINTAAVENPSLIKEIADLIGSANLVVAIDAKWNGKFWEVYTHGGRKPRGMDAVEWAKRVEELGAGEILLTSMDTDGTKQGFDIPLTKAVVDAVNIPVIASGGAGKPEHFLEVFRIGSDAALAASIFHYGEYTVRELKMFLAKNGIPVRLD",
    "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASANPETAKPTPATVDMANPEELKKVFDQFDSNGDGKISVLELGGVFKAMGTSYTETELNRVLEEVDTDRDGYINLDEFSTLCRSSSSAAEIRDAFDLYDQDKNGLISASELHQVLNRLGMSCSVEDCTRMIGPVDADGDGNVNFEEFQKMMTSSSLLNSNGSAAPPST",
    "output": "Potential calcium sensor."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MWIALLGIPILLAVLTLLLKHINKTYFILSLTKRVRTEDGSPLESKVAIMPGKTRFGNNLDILNFTPASVFNFVRESTAKAKGQNYLWYFLYAPMYNVVRPEEAEEVFQSTKLITKNVVYELIRPFLGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEKNLDAELELNQVIPPFTLNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYFFVYGDYRKHLQNLRIVHDFSSRIIERKRQQFQQKQLGEVDEFGRKQRYAMLDTLLAAEADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENLPEDSDDISMFQFNKLVYLECVIKESLRMFPSVPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPENTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQLEDLTFENGIVLRTQENIKVKLSKRVK",
    "output": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAIVSSTTSIIPMSNQVNNNEKGIEDNDHRGGQESHVQNEDEADDHDHDMVMPGFRFHPTEEELIEFYLRRKVEGKRFNVELITFLDLYRYDPWELPAMAAIGEKEWYFYVPRDRKYRNGDRPNRVTTSGYWKATGADRMIRSETSRPIGLKKTLVFYSGKAPKGTRTSWIMNEYRLPHHETEKYQKAEISLCRVYKRPGVEDHPSVPRSLSTRHHNHNSSTSSRLALRQQQHHSSSSNHSDNNLNNNNNINNLEKLSTEYSGDGSTTTTTTNSNSDVTIALANQNIYRPMPYDTSNNTLIVSTRNHQDDDETAIVDDLQRLVNYQISDGGNINHQYFQIAQQFHHTQQQNANANALQLVAAATTATTLMPQTQAALAMNMIPAGTIPNNALWDMWNPIVPDGNRDHYTNIPFK",
    "output": "Transcription factor that acts as a floral repressor. Controls flowering time by negatively regulating CONSTANS (CO) expression in a GIGANTEA (GI)-independent manner. Regulates the plant cold response by positive regulation of the cold response genes COR15A and KIN1. May coordinate cold response and flowering time."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MANQKIRIRLKAYDYALIDRSAQEIVETAKRTGAVVKGPIPLPTKIERFNILRSPHVNKTSREQLEIRTHLRLMDIVDWTDKTTDALMKLDLPAGVDVEIKVQ",
    "output": "Involved in the binding of tRNA to the ribosomes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIVIDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRAHVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERLRINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGPFPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVLSGLDTVKICVAYDLDGKRIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPENARNYVRRVGELVGVRISTFSVGPGREQTNILESVWASI",
    "output": "Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRIAMISMHTSPLEQPGSGDAGGMNVYVLNTARQLARLGVEVDIFTRATRPSQGEVVDVEERLRVINIVAGPYEGLSKEELPTQLAAFTGGIFNFARCFEVDYDVIHSHYWLSGQVGWLLRDLWDIPLVHTAHTLAAVKNVHRTLDDTPETEARRICEQQLVDNADILVVNTAQETRDLIEHYDASPDNIVVVSPGADTDLYTPGTDRMTERARRQLGIPLHTKVVAFVGRLQKFKGPDVLIRATAELMERDPDRRLRVVICGGASGANSSPDTYHNLARELGVERVVRFLSPRPPQELVAIYQAADIVAVPSYNESFGLVAMEAQASGTPVVAAAVGGLPIAVADGDTGLLVHSHSAQDWADALEQLLDDDPRRISMGEAAVDHAQQFSWAAAATQLENIYADAMSIEIPDCHARRAIGY",
    "output": "Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNPLIFTTIVLTIIMGTMIVMTSSHWLTVWIGFEMNMLAVIPILMKNYNPRSMEASTKYFLTQATASMLLMLAIIINLLYSGQWSITKPLNQTASIIMTLAMAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQIFPTINLNLMLLMSVLSVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMAYNPTMTLLNLVIYILLTTTTFMMFMLNSSTTTLSLSHTWNKAPLLTMTILTIMLSMGGLPPLSGFLPKWMIIQEMVKNDNIITPTIMAVTALLNLYFYMRLTYSTSLTMFPSTNNMKMKWQLNNTKSTAHVSPLIILSTLALPLSPILMLLE",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEVRVQNIRKEFGRFPALEDVSLDIRSGELIALLGPSGSGKTTLLRLVAGLESPTEGTIFFGDEDASKKTVQQRNIGFVFQHYALFRHMTVLDNVAFGLKVRPAKRRPSAADIRRRAVDLLELVQLSGLERRYPAQLSGGQRQRVALARAMAVEPNVLLLDEPFGALDAQVRKELRRWLREIHDRTGHTTIFVTHDQEEALELADRVVVMSKGAIEQVGTPDEIYDHPVSPFVYGFIGQSNCLDVTLANGEIWHEDRPIGLRAGNEPDGAATLYFRPHDVELIDGCGGCLAGLVTASRRVAGTRHLELDLGRKHPPVEIELPPERAASTDHTRIAFRPTRWKLFRKGGQKEAPLIEAEAPVLAATGT",
    "output": "Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MYLLIDVGNSRIKWLYGNKVPSTIEAVSYKQDWQMKLIRAWHLLPEPEAIALSSVNKAEITTTIEEIVRQLWHKTVKIFVSQKQTNHTLTVVYQKPEKLGSDRYLAMLGARSLCHDPLCVVGCGTAITLDAVDGDGRHLGGFILPGMRLAENALLQNTQKLVPMRWTPHLLGNDTASCISAGIHHALPAGVDHIIDELEGQCGYYFKRFAFGGDAQILFGNRPTYRIEPDLIFGGMFAHLSPPKQV",
    "output": "Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "METATIIVIFVSSLLLGITTYSVYTAFGPASKNLRDPFEEHED",
    "output": "May play a role in photosystem I and II biogenesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSSAGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV",
    "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEEVPRRQPGGLVEVEGVFQFYEDWECWDYVSQRVPGERLQRWLAMLTNNQLRRQVIREAQIWMWKHKGAAVRRNCGCRLCNPGWGSQVRNVEL",
    "output": "Seems to function as a Vpr-like protein, since it mediates host cell cycle arrest in G2 phase. Cell cycle arrest creates a favorable environment for maximizing viral expression and production."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKPLIIIVGPTAVGKTALGVALAQALQGEIISGDSVQVYRKLDIGSAKPTLAEQGNVPHYLLDALDPAEPFTVAQFQTLANQSIQNIQSRGKVPIVVGGTGLYIRSLIDPFQFAEHGSESIRSFWTAFLSEQGKEALHRELAKRDPLSAQRLHPNDTVRIIRALEMCQLTGKPFSEIRGNQDMNYPPLPPSLLYVGLTAPREIIYERINRRCEQMVAAGLIEETHNLIKEGYSPKLKPLQSIGYRHALLYLYGKVTLPEMMRIFQRDTRHFAKRQLTWFRRDPRVVWYDTYSGNLTNILESLIGTCSGMESRVE",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEARRSGNFKASIWDDDFLQSLTSPYTAKEYLKQADKLKWQVKVIIKETKQRLDQLDLIDNIQRLGISHHFRDEIQRVLQNIYEKMRVECPDRMLMEKDLYSTSLQFRLLRQHGYHVSQDVFCSFMDGAGNFQAVDDLKGILALYEASFLSREGENILGSARDFSTRHLKQKLEEITDPILAEKIRRALELPLHWRLQKLEAIWFINIYESRFDANLILLQLAKLEFNMVQAQYQEDLKWLSRWYKETGLPEKMNFARDRLAECFLWALGFIPEAHLGQARKILTKIAVLIVIMDDFYDIYGTLDEIKVFTEELQRWDINALDNLPEYMRICFLAIFNTANEIAYDILRDQGINIISNLRRLWAELGRVYYTEAKWYHSGYFPSTEEYLNVAWISITGPVLLFHAYFSIMNPIDMKELQYLEQYPGIIRWPSTVLRLADDLGTASDEIKRGDVPKSIQCYMHETGCSEEEAREYVKQLIDTTLKKMNKEILMEKPTNDFGATAMNLARISLFFYQYGDGFGVPHNQTKENLVSLIVKPICLT",
    "output": "Sesquiterpene synthase converting farnesyl diphosphate to trans-alpha-bergamotene as the major product."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITKAFFAHYGERVEAEIISPDKTPDLPNFAEIFARQSSWEWNFGQAPAFSHLLDERFSWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGGLYRADMLQQECEALLVDFPDQEKELRELSTWIAGAVR",
    "output": "Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MHLPRRRRLQRNRIFFFLAVVSLLSVYQLQFSPSAIPALLTAHQHEDPVKVTSREPFRNKTSKTGNVTAAPKIRHCVYIDPEPTVPITASEDTTQRENVNESYPDEKPVYESKGEYPQDLFSVEERRQGWVVLHIFGMMYVFVALAIVCDEYFVPALGVITEKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILHLTWWPLFRDISFYIVDLLMLILFFLDSVIDWWESLLLLTAYATYVFTMKHNVSLEQWVKEELSKKLNAVQAASAEHMRKKSSVAVAEDGTKPADGKKLQPTTALQRGTSSASLHNSQMRSTIFQLMIHTLDPLAGAKFKDRVDILSNIAKVKADSLTGQGTKPEAEEEKQASQNTVQVTPASDSEPSKDKQKEDTPQDGQPPSDSDNSEDSSSDSEDDSDDDSTDDEENDEPLSLEWPETRKKQAIYLFLFPIVFPLWSTIPDVRNPDSKKFFVITFFGSIIWIAAFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWFLYSVFNGFSPVAVSSNGLFCAIVLLFLMLLFVIISIALCKWKMNKILGVTMFALYFVFLIISVMLEDRIISCPVSV",
    "output": "Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) . Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFKVLIITLLVNKIHLEKIYNVPVNCGELHPVKAHEIKCPQRLNELSLQAHHNLAKDEHYNKICRPQLKDDAHLEGFICRKQRWITKCSETWYFSTSIEYQILEVIPEYSGCTDAVKKLDQGALIPPYYPPAGCFWNTEMNQEIEFYVLIQHKPFLNPYDNLIYDSRFLTPCTINDSKTKGCPLKDITGTWIPDVRVEEISEHCNNKHWECITVKSFRSELNDKERLWEAPDIGLVHVNKGCLSTFCGKNGIIFEDGEWWSIENQTESDFQNFKIEKCKGKKPGFRMHTDRTEFEELDIKAELEHERCLNTISKILNKENINTLDMSYLAPTRPGRDYAYLFEQTSWQEKLCLSLPDSGRVSKDCNIDWRTSTRGGMVKKNHYGIGSYKRAWCEYRPFVDKNEDGYIDIQELNGHNMSGNHAILETAPAGGSSGNRLNVTLNGMIFVEPTKLYLHTKSLYEGIEDYQKLIKFEVMEYDNVEENLIRYEEDEKFKPVNLNPHEKSQINRTDIVREIQKGGKKVLSAVVGWFTSTAKAVRWTIWAVGAIVTTYAIYKLYKMVKSNSSHSKHREADLEGLQSTTKENMRVEKNDKNYQDLELGLYEEIRSIKGGSKQTGDDRFFDH",
    "output": "Attaches the virus to host cellular receptors, inducing endocytosis of the virion. The acidic pH of the endosome induces conformational changes in the glycoprotein trimer which trigger fusion between the virus and the cell membrane (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKVRILTVGNKMPKWVQTGFDEYHKRIQPMLTTEVVEIAAAKRAKNPSDANLAQYREQEGQAILAAHAVAGREQLWVLDVKGKMLSTENLADKLSDGMQQGDDIALVIGGADGVSPEVLAKADVKWSLSALTLPHPLVRVVLMEQLYRAMSINHNHPYHRGN",
    "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKGQQKTAETEEGTVQIQEGAVATGEDPTSVAIASIQSAATFPDPNVKYVFRTENGGQVMYRVIQVSEGQLDGQTEGSGAISGYPATQSMTQAVIQGAFTSDDAVDTEGAAAETHYTYFPSTAVGDGSGGTTSGSTTAVVTTQGSEALLGQATPPSTGQFFVMMSPQEVLQGGSQRSIAPRTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKNDSN",
    "output": "Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDGVGKSVKLCGGPIGYIYATPKCSVPVDELAILAAKSNDCDDAVLPLVAGLTVESDFVWNVAAVAGTKTTGLGSGGTTLKLVPTHYHPCVFVFYGGDCIKPCTKAPNLTKACDLARERFGYSAYSSPAPTAFETTGQQICEALEMDAQNVMLYLVVTELFKEVIYLCNSFLHFGGSDVVTINNADVRRIPIYPLHLVLPDFNRITNEPFSEKPRALGEGAIMPKAFYNDSLCRLLHGYVLSTTAVGLRVRNIDAIARGAAHLCFDENHEGTLLPADTTFTAFTPAAETTKGQSKMGKREGSDVSGGGYERRTASLMASDATLAIENVISASVYEDPIPDVNKWPIYCNPVGYADRIEALSAYMARVAGLVGAMVFSSNSVIYMTEVGEAGSTEGKETSTTAPSFYRFFQIAAPHLSANPLVDRDGKPVSGENLSKSTSASQSEYSLDYLILACGFCPQLLARFLFYLERCDGGAKACHHDLDTVKFVSSAIDADMPCELCDKTSRIYCAHTTIKRLVYRLPKFGYQMRGAMGLFGAMTNNYCDVNALGSYAQFSTLKRSEGEASRSVMQDTYRLTVERMMKALEKEGLLTCDDPTNMASADANIRDGNSFIRAISTMKNIIESEASQLMRNLTEIREYNIREGLGDANHTLSLAVEPYASGICPVLAFLSRRTIIAVVQDMALSQCSIVMQGQQVEARNFRTQFQAVLKRRVLELQNAGFITSKTITVTLEDQQICVPDPSKSQYDSVISNMEGDLVKVTVEIFRELKVKNKVLFGGGIAGAASEATKSRLAGMVEAYQRPTKTMHVLNGPLGFAVKRYHTLLFPDVKMPNGATPNALWFWILLLRNQLPAGILSKEEEDKSLFIKKFTKSYADMNYINISPTCFGDLAQFYLANTILKYCSHKHFFINTISALVAVSRRPRDPAIVLPWIERPITKGQDVAPAAQQLIASMSDHKDIWCATFSSTNLVGSIMTTKPFVVIGISISKYHGMAGSTKVFQSGNWGNIMGGRNVCSLMSFDRTHRYVMTCPRVGFVAEQPIFSSGIKETTLIDRVRMVLSEESAAPHAAVYMLALKMVGDRVRQMELEDWMEITNDEYISSLIDELNKQVEEAEGGWNADAAMTLAKEMVNMAMSIPTDGPTFDFDACDENLEGHADGQTISETNLKRPNMNVFDLEPIPEKRVPVLSVDML",
    "output": "Plays several crucial roles in viral infection. Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein. May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation. Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle. Can also catalyze the renaturation of complementary single strands. Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments. This process is driven by the protein which can form double-helical filaments in the absence of DNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNHIHEHLKLVPVDKIDLHETFEPLRLEKTKSSIEADDFIRHPILVTAMQHGRYMVIDGVHRYTSLKALGCKKVPVQEIHETQYSISTWQHKVPFGVWWETLQQEHRLPWTTETRQEAPFITMCHGDTEQYLYTKDLGEAHFQVWEKVVASYSGCCSVERIAQGTYPCLSQQDVLMKYQPLSYKEIEAVVHKGETVPAGVTRFNISGRCLNLQVPLALLKQDDDVEQLRNWKQFLADKFANMRCYTEKVYLVEQ",
    "output": "Free serine kinase that uses ATP to phosphorylate L-serine to yield O-phospho-L-serine and ADP. O-phospho-L-serine serves as a substrate for SbnA and is a precursor for staphyloferrin B biosynthesis . Is also a DNA-binding regulatory protein that senses heme to control gene expression for siderophore biosynthesis. Binds to DNA within the sbnC coding region and is required for expression of genes in the sbn operon from sbnD onward ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDSNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI",
    "output": "Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs). Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell. Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain. This domain is believed to allow recognition of RNPs bound to the protein M1. Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized. Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane. May down-regulate viral RNA synthesis when overproduced."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSRKGSTPQRTVLPDPKHGSETIARFINMVMQSGKKSVAEKIVYGAMDVIGEKNPNAIELVQKALDNVAPAVEVKSRRVGGATYQVPVEVRSSRRMALAMRWLIDSARKRGENTMPRKLAAELLDAAESRGGAIKKREETHRMAEANKAFAHYRW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MESAITISNHVNLAFSLSRNPSLSTKNSAGISCIKWQRPCLRNLGHVRLNQQRKGTRRKSTLVQAVAVPVAQPSAFPPTDNTEHLKQLAERYGFQQIGEPLPDDVTMRDIITSLPKQVFEINDTKAWGTVLISVTSYALGIFMIAKAPWYLLPLAWAWTGTAITGFFVIGHDCAHKSFSKNKLVEDIVGTLAFMPLIYPYEPWRFKHDQHHTKTNMLREDTAWLPIMKEDIESSPGLRKALIYAYGPLRTWMSIAHWLKVHFNLKDFRQSEVKRATISLAAVFAFMVIGWPLIIYKTGIVGWIKFWLMPWLGYHFWMSTFTIVHHTAPHIPFKSSKEWNAAQAQLSGTVHCDYPRWIEILCHDISVHIPHHISPKIPSYNLRAANQSLNENWGEYLNKPKSNWRLMRTIMTTCHIYDKDGNYVSFEKAVPEESQPISIPKRVMPDYA",
    "output": "Chloroplast omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTITQVKIKKLENFSGSLPEYATEHSAGMDLIAANEQPITIKAAAIQLIPTGIAIALPDSFEAQIRPRSGLAVKHGITVANSPGTIDADYRGEIKVILINLGKEDFIIEKGMRIAQMIIAKYERILWEESISLMETMRGSGGFGSTSV",
    "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSESPKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLEEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVNGKSRLLRGLDGNKDQSYFLYTLGHEQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFRDFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKDGSEDPWYVVDKDVENNVLIVAQGHEHPRLMSVGLIAQQLHWVDREPFTGTLRCTVKTRYRQTDIPCTINALDDDRIEVIFDEPVAAVTPGQSAVFYSGEVCLGGGIIEQRLPLTV",
    "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQFHSSSALITPFKKDLSVDEAAYESLIKRQIFQGMDACVPVGTTGESATLTHKEHMRCIEIAIETCKNTKTLSNSRMKVLAGVGSNATSESLSLAKFAQKIGADAILCVSPYYNRPTQQGLFEHYKTIAQSVEIPVMLYDVPSRTGVSIEISTALKLFREVPNIKAIKEASGSLKRVTELHYHEKDFKIFSGEDSLNHSIMFSGGCGVISVTGNLMPNLISQMVNCALKLEYQQALEIQNKLFHLHQALFVETNPIPIKMAMHLAGLIENPSYRLPLVAPSKETIQLLEKTLQQYEVIA",
    "output": "Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDLARSDIIPHLLCLFQEIIQANIQKVSEAYDLELKIMNILTLWRNGSDNLISDNDDYMKKGLFFSRSNDPLALQARYARMYDDLFKLNNYEVPDDVVRRHDNKILDIILKESSVPFWYDISDDEAHESMLPEFRLQDIHEFRLNLKRVRVVPDESEEIQMDESQSDKRRRKKRMEKSRPVWLSGSESDRRIELNDSLKPSQKFETKLSSYLLNRLMNEMNPHYCGHPLPALFVTLIMLKAYSIKNKFFSYGIRYMELVCNEIAGPDLNTRTFPVLFGSDGSFVGTRVYSHYPIKLRMILNDLTYLLTYSDLHKFQEFELDVNDEVLLHMLRTPNDGRQLKKAVTRLNHYYGLKFNPKTTDCGVVNGMDFTHKHPITKTADFTSPVLPMTNSFNKAEICYGHNSKILNRAVFTDTVRGHIREDLKNVADLDLPKLYEHVSKLVDMRVNYTIIYDLMFLRVMLNLGGYSRSNQITDFRKTIDEITKMNEGFLSGADPEKNIDTLNAWMAPTMEDCGYRLTKSILFGKFRKAKYPSDLEAKSNIDYYVTARSAGIGNLRISIETDKRKYKVRTTSKSAFVNAMGSGILDVNPVSNEPMMLTDYLLTQTPETRANLEAAIDSGSKSDSELMRILGQNSIGSRSTTAWRPVRPIYINVLQAHLAQAFIIGPHINATVNQHEYQPTSLWFTGDDLGVGFATLYQSGTADIIVPAIEASSTGKALSVLADCSSWDQTYLTATMIPYYNGIKRALLEYQQADMRNFYMIDSGRTGVPGMKLSEIVDWFNSFQTKRIFNASYLKERHSFVVKYMWSGRLDTFFMNSVQNALITRRIAEEVSLRVSNTGLSWFQVAGDDAIMVYDGSSISTTEQVTRINEITVRNYEESNHIINPQKTVISHISGEYAKIYYYAGMHFRDPSIQLHESEKDSGASDVTESLREFGQVIYEYNKRAIGTLRVNALYGRLIAGLAYSVNCPQYDASKRTYANMKYYPPPTSVIAPAAFKGGLGLSFTGLSLNEVLFIKLHLHEAVSQGLHVISMISFEANEVVSNSLSAYYLKDQKDLLRDMKLGKHLEKVKGISFKSSDLAFSGSDFSQGLNLKRESIDKVKLEVSRKSIRDLRSSGISVPSTHAYENLPYASLHQSFKSLKVDRDTSKFTNERLLVSLLEYKSDIPRVSVTSQYPVYDLINISKVDELNVRSGGPVRFISAPIEGKLLEENIGTRQGVQFKNRGYGGSQEVLHFIRSNGLVITEQALIDLIIKSGVLLMINPQRGLIDLFQSLSGDTASSMHLANFFMAEKPHWEDNAISLTIAGSLLENCDSRIENVKNFVSVLATGMQKDLQRMFYYVGFVYYAQRLIWSGGHSSKIFVSIDEDKLADFLRGSKPITRRRKAMAGTKREPINLSANFSYEISEPDREISEYDPLILCHPLSMPFFGNWQEKYSVMQSDEQM",
    "output": "RNA-directed RNA polymerase that is involved in both transcription and genome replication. Together with the capping enzyme P5 and protein P7, forms an enzyme complex positioned near the channels situated at each of the five-fold vertices of the core."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "LKCHQLIPPFWKTCPEGKNLCYKMYMVATPMIPVKRGCIDVCPKNSALVKYMCCNTDKCN",
    "output": "Shows cytolytic activity on many different cells by forming pore in lipid membranes. In vivo, increases heart rate or kills the animal by cardiac arrest. In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSTPARRRLMRDFKRMQQDPPSGVSASPLPDNVMKWNAVIIGPSDTPFEDGTFRLLLSFDEQYPNKPPQVKFISEMFHPNVYASGELCLDILQNRWSPTYDVSSILTSVQSLLNDPNISSPANVEAANLYKDHRSLYVKRVRETVENSWNDDDDEEEEEEDEDEAEDEDDDDDDNIDED",
    "output": "Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNQLEFVKLHGNGNDFILIDELNGERIPEDEKSEASRILCHRNFGIGGDGVLFLVPSERADIGMRLFQPDGSEAEMCGNGIRCLAKHAWESGYVGERFSVETLAGVIPIQVRRDRKGFWARVEMGIPRFERSEIPADGEGTFLKVPLHGFEVSAVNTGVPHAVIFVENLDIPVEQIAPKIRHSSCFPEGANVNFVRLGNHLEVRTFERGVEAETLSCGTGSVAAAAVARRLGLVGETVEVMTKGGPLRISFAGEKAFMEGPAVTVCRGVVSDEILQTLQ",
    "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRKLALAAIQFYRYAISPLMANHCRFHPSCSCYAHEAISTHGLLRGGWLSLRRLGRCHPWNPGGYDPVPPIKTSRSSSMAE",
    "output": "Could be involved in insertion of integral membrane proteins into the membrane."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MASSSCFLRSILFSSPTNLRSNHHLPTFFPKNYLICSHSTSSRFESLSVSSIGTGSTKKSSDTRRKVKSMATTNIGKEEKKRVEIYDLEENLVIDLAKFTADLSDKFCKERGAFTVVVSGGSLIKSLRKLVESPYVDSIDWARWHFFWVDERVVPKNHDDSNYKLAYDSFLSKVPIPPGNVYAINEALSAEAAADDYETCLKHLVNTNILRVSESTGFPKFDLMLLGMGPDGHVASLFPGHGLCNESKKWVVSISDSPKPPSERITFTFPVINSSAHVALVVCGSGKAEAVEAALKKTGNVPPAGSVSAEDELVWFLDKPASSKL",
    "output": "Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate . Involved in the regulation of cellular redox state; enzymatic activity is required for this function . Required for sugar-dependent expression of nitrate assimilation genes in the nucleus of root cells ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEIKNKTRIGHVISDKMEKTIVVGIDVVKRHPLYKKTYRRTMKYLVHDEKNEAKIGDMIEIVECRPISKGKYWRLSKIITKGHIVAAQEA",
    "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MREILHIQGGQCGNQIGAKFWEVICDEHGIDQTGKYAGDSDLQLERINVYYNEASGGRFVPRAVLMDLEPGTMDSLRSGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLATPTFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDSKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMLNVQNKNSSYFVEWIPNNVKSSVCDIPPTGLSMSSTFVGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVAEYQQYQDATADEEEEYDEEEEEEAA",
    "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDYIVGFVSISLVALLYFLLFKPKHTNLPPSPPAWPIVGHLPDLISKNSPPFLDYMSNIAQKYGPLIHLKFGLHSSIFASTKEAAMEVLQTNDKVLSGRQPLPCFRIKPHIDYSILWSDSNSYWKKGRKILHTEIFSQKMLQAQEKNRERVAGNLVNFIMTKVGDVVELRSWLFGCALNVLGHVVFSKDVFEYSDQSDEVGMDKLIHGMLMTGGDFDVASYFPVLARFDLHGLKRKMDEQFKLLIKIWEGEVLARRANRNPEPKDMLDVLIANDFNEHQINAMFMETFGPGSDTNSNIIEWALAQLIKNPDKLAKLREELDRVVGRSSTVKESHFSELPYLQACVKETMRLYPPISIMIPHRCMETCQVMGYTIPKGMDVHVNAHAIGRDPKDWKDPLKFQPERFLDSDIEYNGKQFQFIPFGSGRRICPGRPLAVRIIPLVLASLVHAFGWELPDGVPNEKLDMEELFTLSLCMAKPLRVIPKVRI",
    "output": "Forms the bisbenzylisoquinoline alkaloid berbamunine by phenol oxidation of N-methylcoclaurine without the incorporation of oxygen into the product. Oxidatively couples either two molecules of (R)-N-methylcoclaurine to form the (R,R) dimer guattegaumerine or one molecule each of (R)- and (S)-N-methylcoclaurine to form the (R,S) dimer berbamunine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKVMDALQSGRRKPLPVALLCILVTVFCVLECHGADLTSPTKKSAPLRITKPQPTSQQAKPISITTRAPTTVASTTDDEVSSSVDGQLAPLISSTTEGPSSGTTASLVPEICLNGLQLTVNSADEGTVIRKQEEFVKILEGDVVLSVLTKDPDSALFVINRVNQANLIMADFEIGIRAISIDNASLAENLLIQEVQFLQQCTTYSMGIFVDWELYKQLESVIKDLEYNIWPIPGTRAHLFPKVAHLLHQMPWGEKIASVEIATETLEMYNEFMEAARQEHMCLMHFKSDDNVYIMFGNKLASHFKENGTLFSVPTDRTDDEFLADLPNRAFVLMENEIDLSTAVELDATPTALDEILIGKSVLPSRVLSFAGSIIDLMNWLRGSLSKHCKRGEEHDLYVLESCFNFLNFIEDWRTSEYRQAHDTAEILSLLLMRKLGTAMNFQMYQKKVLTLDKITGESRTELREIASQNFVTNVTTYYHYNRDNHTSLELKTKFGQVFNCQYSAGDNRRYPFLFDGESVMFWRIKMDTWVATGLTAAILGLIATLAILVFIVVRISLGDVFEGNPTTSILLLLSLILVFCSFVPYSIEYVGEQRNSHVTFEDAQTLNTLCAVRVFIMTLVYCFVFSLLLCRAVMLASIGSEGGFLSHVNGYIQAVICAFSVVAQVGMSVQLLVVMHVASETVSCENIYYGRWLWGLLAYDFALLCCVGALIPSIYRSQRNYREGILIVIGSVLIMVIWVAWIALSLFGDEWRDAAIPLGLQASGWAVLVGILIPRTFLIVRGIERSDIAQALPSLTSLAFAQNNQYSSEQSVYECVNPAMRHCSQDEVNHQSPSEIPTLPLRGGGPRRQQFFANLRQANANINPQRPPPRPQQSPSRSSVSSLPPSPDHNKITRF",
    "output": "Acts as a ligand for sevenless tyrosine-kinase receptor during eye development."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKVNLYISNDAYEKINAIIEKRRQEGAREKDVSFSATASMLLELGLRVYEAQMERKESAFNQAEFNKLLLECVVKTQSTVAKILGIESLSPHVSGNPKFEYSNMVEDIREKVSVEMERFFPKNDDE",
    "output": "Conjugative DNA transfer (CDT) is the unidirectional transfer of ssDNA plasmid from a donor to a recipient cell. It is the central mechanism by which antibiotic resistance and virulence factors are propagated in bacterial populations. Part of the relaxosome, which facilitates a site- and strand-specific cut in the origin of transfer by TraI, at the nic site. Probably autoregulates its own expression. Plasmid specificity is conferred by the TraD-TraM pair (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MADKEATVYIVDLGESMADCHNGRDESDLDFGMRYVWDKISTTVAASRKTWTLGVVGLNTEETNNAQDSEGLEGYEHISVLQDIGPMTMTQLRELRSSIQTSHTYGGDAISGIVVALAMIELFTKKLKYNRRIILVTNGESPIDDESSEDVANRLNYSNIELIVIGVDFDDADYGFKEEDKSKGKARNEKTLRKLVEQCNNGVFGTMQQAVEELAIPRIKPVRPFKAYDGALTLGDPEKYKSALSIHVERYFKTKRAPAPPASTVVVNSEPGGASQSETLNEDTEMGDAEFSGVKHMRTYRVNDPDAPGGKRDVEFEDLAKGYQYGRTVVPFSESDFSITKLETKKSFTILGFIPFSSYNPFLNLGETGIVVAQKHNEEAELGLSALIHALHELESYAVARYVQKDGAQPQLVLLKPNPAIEDDFECLYDVPLPFAEDLRSYQFPPLDKVLTVTGNIIKEHRLLPSEDLKQAMSDFVDAMDLSGFDVDEDGKPTEYAPIDETYNPTIHRMNQAIRARAVDPDAPIKPPAEILLRFSKPPEKLIEKAKPEIEALIDAAEIKKVPAKAQGRGSRKEPVKPLSGLDIDSLLGESKRTTISLDNAVPEFKQILATAADDATIESAAKQMGQIVRKLIQDSFADLFYARAAENLRVMREELISLEVPGLYNKFLTGLKKSILSGELDGDRREMWFKHIVGGHLSLITQDESEVSEVTAEEAKALCAWSRPNITYRYFRDTA",
    "output": "Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTTEPGYLSPSVAVATSMPKRGVGAAVLIVPVVSTGEEDRPGAVVASAEPFLRADTVAEIEAGLRALDATGASDQVHRLAVPSLPVGSVLTVGLGKPRREWPADTIRCAAGVAARALNSSEAVITTLAELPGDGICSATVEGLILGSYRFSAFRSDKTAPKDAGLRKITVLCCAKDAKKRALHGAAVATAVATARDLVNTPPSHLFPAELAKRAKTLSESVGLDVEVIDEKALKKAGYGGVIGVGQGSSRPPRLVRLIHRGSRLAKNPQKAKKVALVGKGITFDTGGISIKPAASMHHMTSDMGGAAAVIATVTLAARLRLPIDVIATVPMAENMPSATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDKPDYLIETSTLTGAQTVALGTRIPGVMGSDEFRDRVAAISQRVGENGWPMPLPDDLKDDLKSTVADLANVSGQRFAGMLVAGVFLREFVAESVDWAHIDVAGPAYNTGSAWGYTPKGATGVPTRTMFAVLEDIAKNG",
    "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTIAFQLAVFALIATSSVLVISVPLVFASPDGWSNNKNVVFSGTSLWIGLVFLVAILNSLIS",
    "output": "Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAIQTQLPCDGDGVCMRCQVNPPSEETLTCGTCVTPWHVSCLLPESLASSTGDWECPDCSGVVVPSAAPGTGISGPESSGSVLVTAIRAIQADVTLTEAEKAKKRQRLMSGGGDDGVDDEEKKKLEIFCSICIQLPERPVTTPCGHNFCLKCFEKWAVGQGKLTCMICRSKIPRHVAKNPRINLALVSAIRLANVTKCSGEATAAKVHHIIRNQDRPDKAFTTERAVKTGKANAASGKFFVTIPRDHFGPIPAANDVTRNQGVLVGESWEDRQECRQWGVHFPHVAGIAGQAAVGAQSVALSGGYDDDEDHGEWFLYTGSGGRDLSGNKRVNKIQSSDQAFKNMNEALRLSCKMGYPVRVVRSWKEKRSAYAPAEGVRYDGVYRIEKCWSNVGVQGLHKMCRYLFVRCDNEPAPWTSDEHGDRPRPLPDVPELENATDLFVRKESPSWGFDEAEGRWKWMKSPPVSRMALDTEERKKNKRAKKGNNAMKARLLKEFSCQICRKVLSLPVTTPCAHNFCKACLEAKFAGITQLRDRSNGVRKLRAKKNIMTCPCCTTDLSEFLQNPQVNREMMEIIENFKKSEEEAEVAESSNISEEEGEEESEPPTKKIKMDKNSVGGTSLSA",
    "output": "E3 ubiquitin-protein ligase. Participates in CpG methylation-dependent transcriptional regulation and epigenetic transcriptional silencing. Mediates ubiquitination with the E2 ubiquitin-conjugating enzyme UBC11."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFAIFQTGGKQYKVQQGEKIYVEKLDLEVGSKISFDQVIMVEGSVGTPFVKNAVVNATVIKQGKQKKINIIKFKSKKHHLKRQGHRQPYTQLVIDSISVK",
    "output": "This protein binds to 23S rRNA in the presence of protein L20."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAGTGHTPEEALALLKRGAEEIVPEEELLAKLKEGRPLTVKLGADPTRPDLHLGHAVVLRKMRQFQELGHKVVLIIGDFTGMIGDPSGRSKTRPPLTLEETRENAKTYVAQAGKILRQEPHLFELRYNSEWLEGLTFKEVVRLTSLMTVAQMLEREDFKKRYEAGIPISLHELLYPFAQAYDSVAIRADVEMGGTDQRFNLLVGREVQRAYGQSPQVCFLMPLLVGLDGREKMSKSLDNYIGLTEPPEAMFKKLMRVPDPLLPSYFRLLTDLEEEEIEALLKAGPVPAHRVLARLLTAAYALPQIPPRIDRAFYESLGYAWEAFGRDKEAGPEEVRRAEARYDEVAKGGIPEEIPEVTIPASELKEGRIWVARLFTLAGLTPSNAEARRLIQNRGLRLDGEVLTDPMLQVDLSRPRILQRGKDRFVRVRLSD",
    "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAEAAPQDAQQNFAIQRIFLKDVSFEAPNSPVMFQKEWNPDVKLDLDTQSRELGEGVYEIVLRLTVTVKNEEETAFLCEVQQGGIFTAEKMEAGQLAHCLGAFCPNILFPYARETISSLVVKGTFPQLNLAPVNFDALFMNYLQQQAQQGEAEA",
    "output": "One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTDMNKWRHIFKLDPAKPISDEDLMKICTSDTDAIMIGGTDDITEENVAHLMHKVKCYSLPIVLEISNLESVVPGFDLYFIPTVLNSRDVKYHNGLLLEALKSYGTLIDFNEVVFEGYVVLNPDCKVAKLTQADTMIDDEDIEAYAQMINDMYQLPVMYIEYSGVYGETNLVKAAADMLTETQLFYGGGISNYEEAEMMASIADTIIVGNIIYEDINKALKTVKVKETH",
    "output": "Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MMRGGMGNMNNMMKQMQKMQKEMAKAQEELGEKTVEGTAGGGMITVIANGHKQILEVKVKEEVVDPEDIEMLQDLVLAATNDALKKADELSNSTMGKFTKGLNLPGGMF",
    "output": "Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKRVAILGSTGSIGVQALDVVGRFPDRFEVVGLAAGRNAPRLLEQIRRFRPRVVSVCDEAAARAVRAEAPPGTEVLSGDAGAVAVASHPDAAFVLAAISGGAGLRSTAAAIEAGKPVGLANKESMVLAGELLMARAAAKGVPILPVDSEHSAIHQSLVGHNRGEVRRLILTASGGPLRCTPEAELATVTPERALKHPNWSMGDKITIDSATLMNKGLEVIEARWLFGVEQQRIDIVVHPESVVHSMVEYVDGSIVAQLGISDMRGPISYAMGHPERMPLDLPPLDLGRLGKLTFEPPDPARFPAYTLAYRALELGGTAPAVLSGADEAAVAAFLARRCSFTGIAEVCADVLEAHVVEPVRSVEQALAASEHGRREAEKRVGARAHAPAGR",
    "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSGVNEIRSTFLNFFAANGHEIVPSSPLVPRNDPTLMFTNAGMVQFKNVFTGVEKRPYHRATTSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKENAIELAWKLVTKEFGLPKDKLTATVYIDDDEAFGLWKKIAGLPESRIIRIAGSDNFWQMGDTGPCGPCSEIFYDHGDKVWGGPPGSPEADGDRFIEIWNLVFMQYEQLEGGVRNPLPKPSIDTGAGLERVAAVLQGKHDNYDIDLFVALIRAIADLTNADPQGPQKASLRVIADHLRASSFLISDGVLPSNEGRGYVLRRIMRRAMRHAQLLGAREPLMHKLVGALTREMGQAYPELIRAEALIKETLRLEETRFRKTLERGLAILDEKSSTLKKGDMFDGDVAFTLYDTYGFPLDLTQDALKSRGISVDQASFTDAMERQRAKARAAWAGSGEAATENVWFPLREKLGATEFLGYETETAEGAVTALVKDGAEVEGLKAGESGAIVLNQTPFYGESGGQVGDTGVMSGDGVRVRITDTQKKAGDLFVHIGTVEQGTLKLGAALQLEVDHGRRSAIRANHSATHILHEALRQVLGDHIAQRGSLVSPDRLRFDFAHPKPISAEELARVEDIANDVVLENAEVTTRLMALDDAREAGARALFGEKYGDEVRVVSMGNAARDQASNAQASNAMGWSVELCGGTHVKRTGDIGLIAVTSESAVSSGVRRIEALTARGARAHANHNLSLAKAAAAELRTTVDEVPARIAALMEERKKLERELSDARKKLAMGGGAAAGGSASGIREVAGVKLMARAVEGVEMKDLKSLVDEAKKQLGSGVVAIVGRAEDGKAGVVVGVTADLTARFNAVELVRAASEALGGKGGGGRPDMAQAGGPDGSKAEAALAAIESAISRAG",
    "output": "Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTVSENSVLETEVLVGGSAMPNERPGAMEPQNLSKMPEGFPRRSTVANGVRSRASRRFLVVGGALLLSLFAIYEMGAVFSIGGITPLEYLVLALFAVNFCWIALAFCSGIAGFLILLRKPRAKDLQVTELHTRTAILMPTYNESPDRVFSAVSVMAETLSQTGHGHAFDWFILSDTTDPDIALLEEQAFLVLRQETHKHSRVYYRRRRKNVARKAGNVADFCRRWGSRYDHLLVLDADSLMESSTITGLAQRMQADPDAGLIQTIPSLINGTTLMARLQQFAARIYGPVIGTGLGWWVQKEGNFWGHNAIIRTEAFMTAAGLPNLKGKPPFGGHIMSHDFVEAALIRRAGWSVVIAYDLPGSYEECPPSIIDLAVRDRRWCQGNLQHSRILPTKGLHWVSRLHLLTGIMAYLSSPFWLMLILTGLMLALQAHFIRPEYFTDQFSLFPTWPIMDSDRALRLFYITMGVLFGPKVFGVLLLLKDGEFARSVGGRIKAIFSVIFEVILSALIAPIMMFIHCGAVMSILMGRDSGWSPQRRDDGSMPWMTLIYRHRWHMLAGVMLGYAAILDSLTLLAWMSPALIGLWIAVPISAWTGSVKIGEVFKRAGILATPEERNPAQICLQAHEARAAYQKHIAEPWTLAQVLKDPALMELHLAMVDKQPLRAAGTPIEAMEAIVHVKVHEARCQQSALAVLNRQEMAMVLANPLMLRSLQKLPEQFVEEDLVSFC",
    "output": "Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTEPVTQPALVIPQLIVGLGNPEPKYDQTRHNIGFAAVDALARAWNISLAENRKFQGQYGEGTAPGGVKIRLLKPLTYMNRSGQAIQAVTSWYKLSGESVLVIYDDLDLPLGKTRLRLSGSAGGHNGMKSAIAHLSTQNFPRLRIGIGKPKNAVNGDNSETVSHVLGKFSATETQLMSLVLQFVVECVELSLKQGVEKAMNRCNSYTVEAPKS",
    "output": "The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MWFKNLTLYRFNKPFAVETEALETALADFTFSPCSSQDVSKFGFSNALGKKGSSLVHSADNRHLICVTKEEKILPGQVIKEALEEKVALIEDEENRKMAKKEKDALKDEIITSLLPRAFSRRSQTHALILPELEMILVDSSSATKAEELLALLRKALGSLPVIPLSFKAPVESNLTEWLKLGSAPLPFEMQDEAELKSEADEGGIVRFKQQDLKEDEVLAHLATGKQVHKLALHFGQSIALLLQSDASVKRLKFSEEFRAGNDEVGTDDPMARLDADFALMGSELVALMHALVAALGGLEEAQV",
    "output": "May be involved in recombination."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKYPTLLDRFLVYVKENTRSDENSTTTPSTQNQVEFAQNILLPEMERIGLQNVHYLPNGFAVGTLPANDPSLTRKIGFIAHMDTADFNAEGVNPQIIENYDGNPIALGTSGYELHPKDFPQLANYHGQILITTDGTTLLGSDDKSGIAEIMTAIEFLIQNPDIKHCEIRVGFGPDEEIGVGADKFDVKDFDVDFAYTMDGGPLGELQYETFSAAGAKIDFLGRNVHPGSAKDQMINAFQMAIDFHNALPETDRPEKTEGYEGFFHLMNMEGSVDTASTTYIIRDFEEEDFQARKQLMLDIAEKMNANFDTPRVIVNLHDQYYNMKKIIEKDMTPINIAKDVMENLGIKPLIEPVRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLETMEKAVDVILGIVAYK",
    "output": "Cleaves the N-terminal amino acid of tripeptides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSGNIGANPIGKKVNISCSLDEAIDELLMESALKSGWSKKREAELRLEDHLRRFSLVPAEEQYIEKKVD",
    "output": "Conjugative DNA transfer (CDT) is the unidirectional transfer of ssDNA plasmid from a donor to a recipient cell. It is the central mechanism by which antibiotic resistance and virulence factors are propagated in bacterial populations. Part of the relaxosome, which facilitates a site- and strand-specific cut in the origin of transfer by TraI, at the nic site. Relaxosome formation requires binding of IHF and TraY to the oriT region, which then facilitates binding of TraI (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSTPRIALIAHDAKKDDIVALAGAYRATLAQCRLVATGTTGGRIAQAHGLDVERKLSGPLGGDLQIGAELADGRVDIVIFLRDPMTAQPHDPDITALVRACDVHDVPVATNVATARVLLDDLARRLTANA",
    "output": "Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "KKGVTLREDDRFPCNAGNCACLPLDSYSYTCQSPTSSTANCEGNECRSEADW",
    "output": "Probable neurotoxin with unknown target. Possibly targets ion channels."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIADGVTETEVLLPDGASEHDYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPGAKQVTIAQLEDVKPLLMKSIHGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHGKLVELMPQSRAKLDANLKDFEAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLGTNIKLGKTSYSEFLSQLANQYASCLKGD",
    "output": "Involved in the high-affinity zinc uptake transport system."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCCQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQENFSQMDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA",
    "output": "Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart. Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein. In brain, involved in cognitive function, such as learning and long-term memory."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQLTVTNDVNGEVYGPLELSGDMMLMDLVALLEVDCAFESGKQQLYFNGKELKPDVEKTLEELGIGNDDLIVIRGQPVSSNSIANSTSAIELDDDAYVEQFRLQLLSNSALRNSLRMPFADIDSLVNDPQQFKTHMGPVIIQRRRMQSAMPTNPYGIPDEEYKKLMTNPEDPEHKKRLQELQDKQLIDEQLRNALEYTPEVFAQVSMLYINMEINGHPVKAFVDSGAQMTIISPRLAEKTELKRFIDNRFIGEARGVGTGKILGRVHQVQVKIETQFIPCSFVVLDSNVDLLLGLDMLKRHQACIDLEKNVLRIAGTETKFLGEAEIPKGTSFDAVGNPQPPVEIKESADHSKKKMKTSFTITPKVKPVKADNLLNNSSPMGNTGRTFPEKTIKQLMDLGFSRQEVIQALVSTNGNAEFAASLLFQ",
    "output": "Probable aspartic protease. May be involved in the regulation of exocytosis. Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MADGTHSTHRNPSTAQLIELALSRGEGELTANGALVAKTGERTGRSPNDRFIVKEPGSEADIDWGTVNKPFEQTVFTALWNRVESYLGDKELFVSDLEVGADPEHYQPVRVTTETAWHQLFARNLFIVPEQFNAADKPIWQIMNAPGFECIPERDGTHSDATVIINFAERKVLLAGLKYAGEMKKSMFSVQNFLLPAKGVLPMHCSANVGIKGDTTLFFGLSGTGKTTLSADPKRFLIGDDEHGWAPGGVFNIEGGCYAKCIDLSQKNEPVIWNAIRFGTVLENVTMDENRVPDYTDSTLTENSRAAYPLEHIELRKEENLGAEPHAVVFLTCDVSGVLPPVSILTKEQAAYHFLSGYTAKVGSTEMGSSSAIQSTFSTCFGAPFFPRPAGVYAELLMKRIESFGSQVYLVNTGWTGGPHGIGKRFDIPTTRAIVDAIVNDDLKGVETEHLAKLNLNVPLAIPGVETKLLNPVNTWEDKAKYAEYAQQLAESFTENFAKYQVPDSIKNAGPNA",
    "output": "Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTGGQSCSSNMIVWIPDEKEVFVKGELMSTDINKNKFTGQEEQIGIVHPLDSTEVSNLVQVRISDVFPVNPSTFDKVENMSELTHLNEPSVLYNLEKRYDCDLIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPSNIAPVSGSSIVESFEMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGLDDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVENFKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVSDRAEQASFKNDVSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYIVDMINKNLDHGSATLNYIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNSSKFKRSRLKNGFILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQPEGEKSSSAGVEANISNQEVKKSARTSTFKTTSSRHREQQITLLNQLASTHPHFVRCIIPNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIMIKLTATIRGYTVRKEITYHLQKLKKTRVIGNTFRLYNRLVKEDPWFNLFIRIKPLLTSSNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDLLNQEKENLRKNESLLNRVKTSSETLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGLQETIREREATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEEIKSFNDKLSSSEEDLDIKLVTLEKNCNIAMSRLQSLVTENSDLRSKNENFKKEKAALNNQLKNKESELLKMKEKIDNHKKELATFSKQRDDAVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSNFQRETKEQEQKKRNSLVESLNDSKIKELEARLSQEISLNQYLNKRISGNSVETNISSTRRSTSYSDDPLDKEDIIKKYYDLQLAFTEITRNLENEIEEKKNLISRLRFTETRLASSSFEDQKIKAQMKKLKKLIQDMDPSIPLDSILNEPLDNCPDKESDINKLMLEVDYLKRQLDIETRAHYDAENAISALHSKFRKIQGESSLSSSDIYKLKFEASEERVKSLEDKLKTMPLRDRTNLPVGDIIKNRDSISKYEEEIRYYKLENYKLQEILNESNGKLSQLTLDLRQSKSKEALLSEQLDRLQKDLESTERQKELLSSTIKQQKQQFENCMDDLQGNELRLREHIHALKQAEEDVKNMASIIEKLKTQNKQKEKLIWEREMERNDSDMQLQETLLELKRVQDVKKILSDDLAHLKERLSAVEDRSQYTDEINRLKEELNCSLKAETNLKKEFATLKYKLETSTNDSEAKISDLLKQLDHYTKVVEMLNNEKDAISLAEKELYQKYEALNTECESLKGKIVSLTKIKQELESDLNQKTDALQISNAALSSSTQKNKEITEKIKYLEETLQLQMEQNSRNGELVKTLQASCNGYKDKFDDEKQKNIDLYEENQTLQKLNTDLQLQLKNLHERLSDTTEKNAWLSKIHELENMVSLETDLKYEEMKKNKSLERAVEELQTKNSQQTDVIELANKNRSEFEEATLKYEAQISDLEKYISQQELEMKKSIRDNSSYRDKVQEMAQEIEFWKSRYESTMIGSKNIDSNNAQSKIFS",
    "output": "Required for cell division."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEQQNKRGLKRKALLGGVLGLGGLAMAGCEVAPPGGVLGDFLRMGWPDGITPEAVAMGNFWSWVWVAAWIIGIIMWGLFLTAIFAWGAKRAEKRGEGEFPKQLQYNVPLELVLTIVPIIIVMVLFFFTVQTQDKVTALDKNPEVTVDVTAYQWNWKFGYSEIDGSLAPGGQDYQGSDPERQAAAEASKKDPSGDNPIHGNSKSDVSYLEFNRIETLGTTDEIPVMVLPVNTPIEFNLASADVAHSFWVPEFLFKRDAYAHPEANKSQRVFQIEEITEEGAFVGRCAEMCGTYHAMMNFELRVVDRDSFAEYISFRDSNPDATNAQALEHIGQAPYATSTSPFVSDRTATRDGENTQSNA",
    "output": "Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQVTETTSEGLKREFQVLLPANELEDRLNTELSNIKGKVQIKGFRPGKVPVAHLRKVYGKSVMADVLQNAVNEANQQIVSDKGLRLALEPQIEFPKDEEQTIIERALDAKGDLAFKVKLEVLPSFELADLSDVSIKKLVLKPSDEEVNETLERMAKDSRSFEPREEGAEAQSGDRVTIDFVGRIDGTEFEGGKGEDVDLELGSNTFIPGFEDQLVGAKVGDARLVKVAFPADYQAEQLAGKDAEFDVTVKAVAAPGETKIDDELAKRFGMDDLEKLKEAVSKAVGADYEAQSRRKLKKELLDALDGKYAFDLPPSLVHQEFAAVWAQVEQDLKNRGKTFEDEGTTEEASQAEYRKIAERRVRLGLVLAQVGETADIKVSDDEVNQALFARIRQFPGQEKQVYDFYRNNPQALAELRAPLFEEKVVDHVLGQVQVVEEPVSKEALFAEDDEADAVTGAAATDEKPSESSNEAAADKAAG",
    "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDMKKRIHLELRNRTPSDVKELVLDNCRSNEGKIEGLTDEFEELEFLSTINVGLTSVTNLPKLNKLKKLELSDNRISGGLEVLAGKCPNLTHLNLSGNKIKDLSTIEPLKKLESLKSLDLFNCEVTNLNDYRENVFKLLPQLTYLDGYDKEDKEAPDSDAEAYVEGLDDEDDEEDEGEEEDYDEDAAPGEEDEEEGEEDDEEEGEEEEEEDISGEEEEEEELNDGEVDDEEDFEEERGLKRKRELDEEGEEDDD",
    "output": "Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNPLLELLDVHRTYQIGETTVNALRGVSLTIDRGEFVAIMGASGSGKSSLLQILGLLDNPDKGEFKILGNNVNTLSEDEQAGVRNNVAGFVFQQFHLLKRMTIVDNVRLPHIYSGLKGDFRQEAIARLKLVGLEERIDHTPNQLSGGEQQRVAIARALVRDPLIIFADEPTGNLDSKNSAEIMKIFTALHEEGKTIIMVTHENDIAAYACRVIIMKDGLIVSDERKAEMQPSRAVTGESAFDISGSGKGSIWQDGRFTGFMAQAFQSILANKMRTFLSVLGIFVGVASVIAMMALGEGAKSAMQEQLKSMGSNMLSIRGGSAKIRGAAQGAGAVARFSFNDVNDIASLGKLVKNASGVVNGSARIVYGNKNWSSTLTGVGFDYGTMRASIPAIGRWFTREEIQIREKSAIIGVTVVKEIFGSSNPIGKTIKINRINFKVIGIAPAKGFSGPQDEDDVVIIPVTTAMYRVLGKDYLSSIFVEVASPGLMGQAKTAITELIRKKHRLEEGDDSFNIRDMTEIQKMLSSTTQTMSLLLGSIAAISLLVGGIGIMNIMLVSVTERTREIGLRKAIGARKNDIMLQFLIESVGMTISGGLIGVFAGVGISLILAFFAGWAVKTSLLSVVLATTFSALIGVFFGLWPARKAAALKPVEALRYE",
    "output": "Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIKVAVNGAAGRMGGRLITAIKETEGLQLTGALEHAESPMLGQDAGLTAGCGPLDVLISSDLDEVLKATDVLIDFTFPEVSLRNLEACVRHDKSIVIGSTGFTPEQRARVDEMAQNIPVVLAPNMSVGVNACFKLLKEAAQILGDGFDVEIVELHHNKKKDSPSGTAVRMGEIVADALGRDYNKSAVYHREGMCGARTPEEIGMQTVRGGDIVGEHTVYFIGMGERIEITHRAMSRDMFARGAVRAASWLAGKAPGLYDMQDILGLK",
    "output": "Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLNPPLNQLTSQIKSKYLIATTAAKRAREIDEQPETELLSEYHSFKPVGRALEEIADGKIRPVISSDYYGKE",
    "output": "Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIVEPTVATYNTSDFRKGLKVQIDGEPYLITEMNFVKPGKGNAMYKCKMKNLIRGTTLDRTYKGGDSLEAADVETTTVQFLYRQGQDYVFMDGTTFEQYEVPNEVAGDIWKYLKDGTECSMTLYNGAAIIVEPPQHVQLEVTECGPGTKGDTATNVTKPAMVETGAEFNVPGFIKEGNIIKINTLNNEYVERVNN",
    "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRMLDDARDVIRNTQTLPDWYADWAQEAKLRLENAAQSALRPVINLTGTVLHTNLGRALQAQEAIEAVTQAMRAPVTLEYDLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNENTGLLMKVHTSNYSIEGFTKTVEEAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEPMPQQLIAAGVSLVSFSGDKLLGGPQAGIIVGKKAMIAQLQSHPLKRALRADKMTLAALEATLRLYLHPEALAEKLPTLRLLTRSEASIREQAQRLQARLAARYGDEFALEVKPCLSQIGSGSLPVDRLPSAAMTFTPHDGRGSRLEALAARWRTLPVPVIGRIYDGRLWLDMRCLEDESRFMEMMLK",
    "output": "Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGSLSSSDYSKKPHAVCIPYPAQGHINPMLKLAKLLHYKGFHITFVNTEFNHKRLLKSRGSDSLKGLHSFQFKTIPDGLPPSDVDATQDIPSLCESTTTHCLVPFKQLLQKLNDTSSSEVPPVSCVVSDAVMSFTISAAQELDIPEVLFWTPSACGVLGYMHYAQLIDKGLTPLKDASYFSNGFLDQVLDWIPGMEGIRLRDLPTFLRTTNPDEYMIKFILQETERSKKASAIVLNTFQELESEVIDSLSTLLPPIYPIGPLQILQNQVDDESLKVLGSNLWKEEPECLEWLDTKDPNSVVYVNFGSITVMTNDQLIEFAWGLANSKQNFLWIIRPDLISGESSILGEEFVEETKERGLIASWCHQEQVINHPAIGGFLTHNGWNSTIESISSGVPMICWPFFAEQQTNCRFCCNKWGIGMEINSDVKRDEVESLVKELMVGEKGKEMKKKALEWKNIAEVTTTKPDGSSYSNLEKLIKVLKSKPSH",
    "output": "Iridoid glucosyltransferase acting exclusively on 7-deoxyloganetin. No activity with 7-deoxyloganetic acid."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "VAVGNNVLDTLGRSRQSFGGKVRQAMNVPKGKGSRGVVKAMFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGIAAKVLKSMGINLKDARVEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGSEHLLLGLLREGEGVAARVLENLGADPSNIRTQVIRMVGENNEVTANVGGGSGTNKMPTLEEYGTNLTKLAEEGKLDPVVGRHPQIERVVQILGRRTKNNPCLIGEPGVGKTAIAEGLAQRIASGVVRETSEGKKVITLDMGLLAAGTKYRGEFEERVKKLMEEIKQSDEIILFIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYRKHIEKDPALERRFQPVKVPEPTVDETIQILKGLRERYEIHHKLRYTDESLVAAAQLSYQYISDRFLPDRAIDLMDEAGSRVRLRHAQVPEEARELEKELRQITKENEAVRGQDFEKAGTLRDREIELRAEVSAIQAKGKEMSKAESETGDEGPMVTESDIQHIVSSWTGILVEKVSTDESDLLLKMEETLHKRVIGQDEAVKAISRAIRRARVGLKNPNRPIASFIFFGPTGVGKSELAKALAAYYFGCEEAMIRLDMSEFMERHTVSKLIGSPPGYVGYTEPPQLTEAVRRRPYTVVLFDEIEKAHPDVFNMMLQILEDGRLTNSKGRTVDFKNTLLIMTSNVGSSVIEKGGRRIGFDLDYEKDSSYNRIKSLVTQELKQYFRPEFLNRLDEMILFRQLTKLEVKEIADILLQELFERLKKKEVELQVTERFKERVVDEGYNPSYGARPLRRAIMRLLEDSMEEKMLAREIKEGDSVIVDVDSEGKVTVLNGGSGTPTTSLEEQEDSLPVA",
    "output": "May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSIRVTQKSYKMSTSGPRAFSSRSFTSGPGARISSSSFSRVGSSSSSFRGSMGTGVGLGGFGGAGVGGITAVTVNQSLLSPLKLEVDPNIQAVRTQEKEQIKSLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTSRSNMDNMFESYINNLRRQLEALGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQIHEEEIRELQSQISDTSVVLSMDNSRSLDMDGIIAEVRAQYEDIANRSRAEAETMYQIKYEELQTLAGKHGDDLRRTKTEISEMNRNINRLQAEIEALKGQRASLEAAIADAEQRGEMAIKDAQTKLAELEAALQRAKQDMARQLREYQELMNVKLALDIEITTYRKLLEGEESRLESGMQNMSIHTKTTSGYSGGLSSSYGGLTSPGFSYGMSSFQPGFGSAGGSNTFSRTTKAVVVKKIETRDGKLVSESSDVVSK",
    "output": "Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDPNQTNVVPPALHLVDPQIQLTITRMEDAMGQGQNSADPKVYPIILRLGSQLSLSMARRNLDSLEARAFQSTPIVVQMTKLATTEELPDEFVVVTAK",
    "output": "Plays a role in the inhibition of host innate immune response by targeting the mitochondrial-associated adapter MAVS. Mechanistically, usurps the E3 ligase ITCH to trigger the degradation of MAVS, TRAF3, and TRAF6. In addition, causes mitochondrial elongation by triggering ubiquitination and proteasomal degradation of dynamin-like protein 1/DNM1L."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "ALWKNMLKGIGKLAGQAALGAVKTLVGA",
    "output": "Has antimicrobial activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MHNESPIIRRKSTRIYVGDVPIGDGAPIAVQSMTNTRTTDVAATVAQIKALENVGADIVRVSVPTMDAAEAFKLIKQQVSIPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVDCARDKNIPIRIGVNGGSLEKDLQMKYGEPTPEALVESAMRHVDILDRLNFDQFKVSVKASDVFLAVDSYRLLAKKIDQPLHLGITEAGGARAGAVKSAVGLGMLLAEGIGDTLRISLAANPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVISTVNALEERLEDIITPMDVSIIGCVVNGPGEAEVSHLGLAGSNKKSAFYEDGKRQKERFDNEDLVNQLEAKIRAKAARMDESNRIDIKVQN",
    "output": "Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPRRRVAAKREILDDPKYGSQILAKFMNHVMESGKKAVAERIVYGALDTVKARKNSDPLEIFEKALDAIAPLVEVKSRRVGGATYQVPVEVRPSRRNALAMRWLVDYARKRGEKSMALRLAGELLDAAEGKGAAVKKREDVHRMAEANKAFSHYRF",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGVGSSLRMQLTAQKPRVDRFVVPRYSLPEIHRRMTWSDRCEKYNGEIWSSKYLQQKRYINFLDEAFGLAPLKAQQRNSDTFDDWCWPCAPRKKSYLSTADNVLDLPSYSITSFPDVLDWSHDDILVAALGKKYHKWSWRTQSPVDQGQTMFDIRCCKFDPKGKRLLLGTDMRVEVHNELSKCQFVQYCKCNIQICTITAIDWSPTGNSFVTGCSRGRICAMNEKDFPIKSLVLIEGAMLVVKISPNARYVAVAGVHKHRVWILSWPDLIRFRFMKTNEIVKDLNWHPWQTALLGVATLSSDRHASMIIWEPHATDKLRQQDVGRGRYSIDAMRFNNKTGELLLSLWSLDVNVPYPKSSELVVMSNFDTVVDHWGESHTGLNRIRTMVFSPDGTKLATATADEDLIIWNFLPNDYKKILARKKFTAFPQFLDICSYGYTIR",
    "output": "Controls wing pigmentation patterning, possibly by regulating scale cell development . Probably acts as an activator of the anaphase promoting complex/cyclosome (APC/C) that promotes the ubiquitin ligase activity and substrate specificity of the APC/C (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIGTATRAGKQIVERILEEESDEALKMTIASVPASRYLTDMTLEEMSRDWFMLMPKQTVAGSLCIRMDQAIMDKNIILKANFSVTFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGGLIGGLEWNDNTVRVSETLQRFAWRSSNEDGRPPLPPKQKRKMARTIESEV",
    "output": "Prevents the establishment of the cellular antiviral state by inhibiting TRIM25-mediated RIGI ubiquitination, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors IRF3 and IRF7. Prevents human EIF2AK2/PKR activation, either by binding double-strand RNA, or by interacting directly with EIF2AK2/PKR. This function may be important at the very beginning of the infection, when NS1 is mainly present in the cytoplasm. Also binds poly(A) and U6 snRNA.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAFTLPELPYAPNALEPFFDEATMRLHHGKHHQTYVNNLNAAIEKHNELDDLSLEELLTDLSAIPEDIRTAVRNNGGGHLNHSQFWLWLRPNTDGSENHADGEIGDAIAKEFGSFETFKTEFKAAATGRFGSGWAWLVVDEAGKLKVVSTANQDNPISEGLTPVLGLDVWEHAYYLKYHNVRPDYIEAFFNLVNWDKVNELYAKAK",
    "output": "Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLQALQKLLGDPNERKIRKYLPVVKLINSLEIEIASLSDAELRAKTTEFRQRLDRGESLDDLLPEAFAVVREAAKRVLNLRHYDVQLIGGMVLHEGQIAEMKTGEGKTLVATLPAYLNGLTGKGVHIVTVNGYLARRDSEWMGQVHRFLGLTVGLVQEGMSTDEKRRSYHCDITYCTNSELGFDYLRDNMATDIKEVMQRPFNYCIIDEVDSILIDEARTPLIISGQMARPSEKYLKAAQVARELIRDEHYEVDEKARNVILTDEGFEAAERLLGVSDLFDPKDPWAHFVFNAVKAKELFIRDVHYIVRNQEVVIVDEFTGRVLPGRRWSDGLHQAVEAKEGVPIQNESQTLATITYQNLFLLYPKLSGMTGTARTEEAEFSKTYNLEVTVIPTNRPIRRKDAPDLVYKTENAKWKAVAEEIAHMHAQGRPVLVGTTSVEKSERLSAMLKEMGIPHNLLNAKPENVEREAEIIAQAGRKGAVTIATNMAGRGTDIILGGNAEYMARLKLRERLMPKLVQLDPDNPLGSASTTSRGGGQGFGPASPKPKKSWTVVSPNFYPCELSARTSQALDEVVAAAVAKYGLNRLPELVVEDLIAVASEKAPVQDPLILQLREVYNSIKAEYEKVTEAEHEEVVRLGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSSRFFLSLEDNLLKIFGGERVAKLMDMFRVDEDMPIEHPLLSSSLENAQRKVEVYYFDLRKQVFEYDEVMNNQRRAIYSERRRILEGENLKPKILDYMRKTVEEIVRAHVNPELPPEEWEIDKLTAKMQEFVPLLKENLKADDLRDLSYQEILDHLIKQAELAYEAKEAFLDTFEPGLMRKAERFFLLQQVDTLWREHLQQMEALREAVGLRGYGQRDPLIEYKNEGYELFLEMMDNIRRNTVYNLFVFTPQLVQVPQVAQAVPAQAVAASPETGGVVEADFAED",
    "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPLTWKDSGLRWYWVVVLVFLADQLSKQWVLANFDLFESVQLLPFFNFTYVRNYGAAFSFLSEAGGWQRWLFTIVAVGFSSLLTVWLRKQSASLLKLNLAYTLVIGGALGNLVDRLMHGFVVDFIDFYWGKSHYPAFNIADSAIFIGAVLIIWDSFFNSQSEQDKTEEVK",
    "output": "This protein specifically catalyzes the removal of signal peptides from prolipoproteins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNIHEYQAKAIFADNGILTLKGKVAFSVDEAVSNAKELGGSVWAVKAQIHAGGRGLGGGVKIAKNLDEVKDYASKILGMNLVTHQTGPEGKLVQKLYIESGANIVKEYYLAILFNRMAEQITIIASSEGGMDIEKVAKESPGKIAKVGIDPQIGFKMFHGLEVARVLGLDKDEGKKLISMIAKLYKLYMDKDMNMLEINPLIKTAEGDFYALDAKCSFDDSALYRHPEIAELRDITEENPAEREAAEFGLSYVKLDGDVACMVNGAGLAMATMDIINYSGAKPANFLDVGGGASPETVAKAFEIILRDKNVKVIFINIFGGIVRCDRIANGILEATKNVEVNIPIVVRLDGTNAAEAKTILDNSNLKNIKAATNLKNGAELVKSLVG",
    "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKAPCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPMLRMKDGSYHKDGEFTPVSWEQAFDVMEEKFKTSLKEKGPEAIGMFGSGQWTIWEGYAAAKLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAEMHPILWSRITNRRLSDPNVKVAVLSTFQHRSFELADNGIVFTPQSDLVILNYIANYIIQNNAVNQDFFTKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFDEYKAFVAEYTLDKTAEMTGVPKDQLEQLAQLYADPNKRVISYWTMGFNQHTRGVWANNLVYNLHLLTGKISQPGCGPFSLTGQPSACGTAREVGTFSHRLPADMVVTNEKHRDICEKHWQIPAGTIPAKVGLHAVAQDRALKDGKLNVYWVMCNNNMQAGPNINEDRMPGWRDPRNFIIVSDPYPTVSALSADLILPTAMWVEKEGAYGNAERRTQFWRQQIKAPGEAKSDLWQLVQFSRRFKTEEVWPEALLAQKPELRGKTLYDVLFATPAVSKFPLSELKEDQLNDESRELGFYLQKGLFEEYAWFGRGHGHDLAPFDDYHNARGLRWPVVEGKETQWRYSEGNDPYVKAGEGYKFYGKPDGKAVIFALPFEPAAESPDNEYDLWLSTGRVLEHWHTGSMTRRVLELHRAFPEAVVFIHPLDAKARDLRRGDKVKVSSRRGEVISIVETRGRNRPPQGLVYMPFFDAAQLVNNLTLDATDPLSKETDFKKCAVKLAKV",
    "output": "Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTRSLKKNPFVANHLLRKINKLNTKAEKNLIVTWSRASTIIPTMIGHTIAIHNGKEHLPIYITDRMVGHKLGEFAPTLNFRGHAKNDNKSRR",
    "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLKAIATTLGISVTTVSRALGGFSDVAASTRERVEAEARRRGYRPNTQARRLKTGKTDAIGLVYPENDVPFNSGVFMDMVSCISRELAYHDIDLLLIADDEHADCHSYMRLVESRRIDALIIAHTLDDDPRITHLHKAGIPFLALGRVPQGLPCAWFDFDNHAGTWQATQKLIALGHKSIALLSENTSHSYVIARRQGWLDALHEHGLKDPLLRLVSPTRRAGYLAVMELMSLPAPPTAIITDNDLSGDGAAMALQLRGRLSGKEAVSLVVYDGLPQDSIIELDVAAVIQSTRSLVGRQISDMVYQIINGASPESLQITWTPIFYPGSTVHSPSF",
    "output": "The raffinose (raf) operon is negatively controlled by the specific binding of raf repressor to raf operator (rafO) DNA. Binds raffinose as an inducer."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKMKAYAKINIALDAIGKREDNYHLLRMIMQTVDLYDVIDIEKSNDSNISISCNKHYVSTDERNLAYKAAVLFRDEFNIKDGVKINIKKNIPVAAGMAGGSTNAAAVLVIMNKLFNVNASLEVLKEIGLKIGADVPYCIEGGTALCEGIGEIITPLKPFENKILVVLKPNFGVSTKEVYTNLDINKIRKHVNIEGLIQAMENDDLDYVSKNMKNVLENVTLKKHTILKNIKEDMRKSGALGAMMSGSGPTVFAFFDDMLTAQRAFEFLKGKYKYSDVYITRTINSNNL",
    "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "ATVPAGTSVYQQPAVQYQQYQPYQTVVQSQPQQVVAGRVVPAVYPATVGSQVYPSGVVPATVYNSGIVRNVYPAGVVPAVAGAYQYFPTD",
    "output": "Component of the cuticle of migratory locust which contains more than 100 different structural proteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNILVIKSSVNEKKGSYSSHLSDLFIKFYLEIHPEDQIEVYDLNQFGLANTNLTMKNFEDKTFYQKAESDFWINKLRNADKIVFSTSMTNFNYSATTKNFFDAITVPNKTFLLDKNTGKYTGLLKNIQNVQILTAQGAPLGWYPFGNHSALIKQIFEFLGAKVRSDFFVLDGTKVAPNNQKPIADFVAQRQNQIKILAENF",
    "output": "Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNKKELFDAFDGFSQNLMVTLADIEAMKKQVQGLVEENTILRLENTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRELLDRK",
    "output": "Involved in initiation control of chromosome replication."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRTIKEIALESGYSPATVSRLLNNDPNLSITADTKNKILEIANKLGYWEDHQEKKIKPTIALLYRVNHNEQLQDEYFTSLKQALVSTVERDALKMKTFYDIEDLIKNASLFQGFIGVGAEPIENAQLVKLHKVLPNGVFVDTNPAPELFDSIRPNLPFTVKNAIDLFIKNGINKIGFIGGVGPKHDHIQENDLRSITFVEYMKTRGMDTKWTCVEGPVSVENGYKLGKMVLAKYKNDLPEAFLIASDTLAVGVLQAFNEENVNVPKDTKILSINNSNVVKYVSPPLSSFNINQQEMIDMALDTLTHLIIRPDRPNIDIRMNTNLVVRKSFVPQEK",
    "output": "Negatively regulates the transcription of the lactose utilization genes lacL and lacM."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MISLNSIFLLSLVGLSRAAPSRSETSPDRTIKPRAACTPTAGGSSSTDDVPAIQEAITSCGDGGTIVIPADTTYYLNSVLDFKGCSNCDFQVEGLLQFTSSTDYWNGKTAMISVSDIDGLKLRSVTGSGVIDGNGQESWDKFAEDSSYKRPTLLYITGGSNIEVSGLRQKNPPNVFISVKGDTSNAQFTSLTMDATSNSDNLPKNTDAFDIGASTYVTISSVAITNDDDCVAFKPGANYVTVENVSCTGSHGISVGSLGKSSDDTVQNVYARNITMINSSKAAGIKTYPSGGDHGLSTVKNATFEDFIVDGCDYAFQIQSCYGEDDTYCEENPGDAVLEGIVVKGFTGTTSDKEDPVVANLNCGSKGTCDVTISGFEVKAPSGDAKILCGNTPSDLGVTCSSGASG",
    "output": "Pectinolytic enzyme involved in the degradation of xylogalacturonan (xga), a galacturonan backbone heavily substituted with xylose, and which is one important component of the hairy regions of pectin. Activity requires a galacturonic acid backbone substituted with xylose (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAPKRKLSDSDAPEVVHPSRQVQVYGDEPKPAKKRKSEPAFNKKQAHASSVNTIKKKIRDITRKLERAQDLPADVRVEDERALAAYQQELASAEAEKIRQKMIKKYHMVRFFERQKATRQLKKLRKRLLDSESTEEVEQLKDEMHILEVDLNYTQYHPLSETYISLYPPKGSGEDAEVKATKEKPPMWKEVEKCMEEGTLDRLRNRKPEATVSTTKPVRLPERKLVKPKSIPKPKPVEQAPAIDTTGMNRRQRRAQRGVKDSRATKIAKNKSTGFSKNQAFGAVEGARADEAQDGNVSDGGFFEE",
    "output": "Involved in rRNA processing."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVLSNVKIFRLKSHRAFRIGPMIKAVAGNLLVKRFYQPKLERIPPASLLLKQKIRLAQNGSTTSTENPISFSQTMSEIFSVLQPSAPDLDEDKTSGLKRDHLLTERLNNGELGVIMNKFFNPSSTHNNQLIDTNILLQNFPKLSGNDLDLLDFAINEKMRGNWNDLKQDFIQLWYYKSFGFLGPRTQFVLTNSSPSLRSQFLKLPFTEYNWFLLQNNKNANILPADVQNVVKVFHLDDKRFTWKSIDPFSKAIISFVVFVSIYVWLDESAKQKTKELPAQKSTVISE",
    "output": "Involved in respiratory growth and required for cell survival in the absence of prohibitins or GEM1."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MWQFRIFLLFASTWGISGVSAHPDPVFSSSEGAHQVLRVRRANSFLEEVRAGSLERECMEEICDFEEAQEIFQNVEDTLAFWIKYFDGDQCSTPPLDHQCDSPCCGHGTCIDGLGGFSCSCDKGWEGRFCQQEMGFQDCRVKNGGCYHYCLEETRGRRCRCAPGYELADDHMHCRPTVNFPCGKLWKRTDKKRKNFKRDIDPEDEELELGPRIVNGTLTKQGDSPWQAILLDSKKKLACGGVLIHTSWVLTAAHCLESSKKLTVRLGEYDLRRRDPWELDLDIKEVLVHPNYTRSNSDNDIALLRLSQPATLSKTIVPICLPNSGLAQELSQAGQETVVTGWGYQSDKVKDGRRNRTFILTFIRIPLAARNDCMQVMNNVVSENMLCAGIIGDTRDACDGDSGGPMVVFFRGTWFLVGLVSWGEGCGHLNNYGVYTKVGSYLKWIHSYIGERDVSLKSPKL",
    "output": "Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKISANSIRTGNILVYNNDLWVVSKQPEHTQPGKGGAYVQVEMKNLKTGTKRNERFSSSDHLEKAELEQKDYQFLYFEDNNIVLMDNQTFEQISVNKEILDEKLPFLTENMIVKVEFYNEKPLSIELPATVILEIIETDPVIKGATATASYKPATLANGVKVKVPQYLEIGEKIVVKTEDLTYVERSK",
    "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNIALIAHDEKKEDMIQFTTAYTHVLSKHRLFATGTTGMKISNATGLQIHRFQSGPLGGDQQIGAMIANGEMDMIIFFRDPLTAQPHEPDVSALMRLCDVHQIPLVTNIAGAEIFIHGLSRGDLKWREIIKERQEKEGTP",
    "output": "Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGEQLKKQPVLRGGGFTFKQFFVAHDRCAMKVGTDGVLLGAWVPVLHARRVLDIGCGSGLIALMIAQRSLPQVQIDGVELEPAAAQQASSNVELSPWAERIHIHQQDIHQFAENHPHQYDLIVSNPPYFAPAIACRDEARDTARYTGSLTHDALLNCAEKLITEDGMFCVVLPHELGIEFARLAGQQGWFVRCQVDIRDRPGKPLHRMLLTLSRQAGETVYQHLALRQSEGVYSPEFCQLISDFYLNY",
    "output": "Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE",
    "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDTAGIRLTPKEIVSKLNEYIVGQNDAKRKVAIALRNRYRRSLLDEESKQEISPKNILMIGPTGVGKTEIARRMAKVVGAPFIKVEATKFTEVGYVGRDVESMVRDLVDVSVRLVKAQKKSLVQDEATAKANEKLVKLLVPSMKKKASQTNNPLESLFGGAIPNFGQNNEDEEEPPTEEIKTKRSEIKRQLEEGKLEKEKVRIKVEQDPGALGMLGTNQNQQMQEMMNQLMPKKKVEREVAVETARKILADSYADELIDQESANQEALELAEQMGIIFIDEIDKVATNNHNSGQDVSRQGVQRDILPILEGSVIQTKYGTVNTEHMLFIGAGAFHVSKPSDLIPELQGRFPIRVELDSLSVEDFVRILTEPKLSLIKQYEALLQTEEVTVNFTDEAITRLAEIAYQVNQDTDNIGARRLHTILEKMLEDLSFEAPSMPNAVVDITPQYVDDKLKSISTNKDLSAFIL",
    "output": "ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRARNQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVTLLTPEQVQSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRQDELQQEASRRQQALQQALAEEEKAQPQLAALSLAQPARNLRPHWERIAEHSAALAHIRQQIEEVNTRLQSTMALRASIRHHAAKQSAELQQQQQSLNTWLQEHDRFRQWNNEPAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLNALAAITLTLTADEVATALAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGATLRGQLDAITKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITLQPLDDIQPWLDAQDEHERQLRLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLPQEDEEESWLATRQQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWRQVHEQCLALHSQQQTLQQQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDADNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQLTRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVKKINGLGYSKLESTFAVK",
    "output": "SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTTTLTTDLNADAGESFGHWPLGDDARLFPLLTSVNLALGFHAGDPVTLHSAVRLARQHGLGIGAHPGYPDLVGFGRRELALTPLEIQAATLYQIGALQAFLTVEGGTLQHVKAHGALYMRIHEDRAAGEAFCHAVQQLVPQAYLIVLAGAAGSDLALTAAAHGLRVRREAFPERAYTGDGRLASRQLPGSSIHDPAEAARRAVGMAQGWVQTLGGERLALEMDTLCIHGDNPQAVAIAGAIRAALAENGVTLARLHD",
    "output": "Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEPRQILVTSALPYANGSIHLGHMLEYIQTDMWVRFQKLRGNQCIYVCADDAHGSAIMLRAEKEGITPEQLIANVQAEHSSDFADFLVDFDNFHSTHSDENRELSSLIYSRLREAGHIATRSVTQYFDPEKGMFLADRFIKGTCPKCAAEDQYGDNCEKCGATYAPTELKNPKSAISGATPVLRDSQHFFFKLPDFQAMLQQWTRSGTLQDAVANKLAEWLDSGLQEWDISRDAPYFGFEIPGEPGKYFYVWLDAPIGYMASFKNLCARRPELDFDAFWHEGSKAELYHFIGKDIVNFHALFWPAMLEGAGFRKPTAVNVHGYLTVNGAKMSKSRGTFIKARTYLDHLQPEYLRYYYAAKLGRGVDDLDLNLEDFVQKVNSDLVGKVVNIASRCAGFIHKGNEGVMVGGDAAPELTEAFLAAAPSIAEAYEARDFGRAMREIMALADRANAWIADKAPWSLAKQEGKQDEVQAICAQGINLFRQLVIFLKPVLPVLAADAEAFLNVAPLTWNDHLTRLENHQLNPFKALMSRIEPAKVEAMVAASKEDLLAAEAKAPAGNGELAKDPLSAEIEFDTFAAVDLRVALIVKAEAVAGADKLLQLTLDIGDERRNVFSGIKSAYPDPSKLEGRLTMMVANLKPRKMRFGVSEGMVMAAGPGGEEIYLLSPDSGAKPGQRIK",
    "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKNIRNFSIIAHIDHGKSTLSDRLIQTCGGLSDREMEAQVLDSMDLERERGITIKAQSVTLNYKAKNGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMNLEVVPILNKIDLPAADPERVAEEIEDIVGIDAMEAVRCSAKTGVGIEDVLEEIVAKIPAPKGDPNAPLQALIIDSWFDNYLGVVSLVRVKNGVLRKGDKIKVMSTGQTYNVDRLGIFTPKQVDKNELECGEVGWVVCAIKDILGAPVGDTLTSQHNPASSVLPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPETSTALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVELTNGDVIYVDSPSKLPPLNNISEIREPIAECNMLVPQEYLGNVITLCVEKRGVQTNMVYHGNQIALTYEIPMGEVVLDFFDRLKSTSRGYASLDYSFKRFQAADMVRVDIMINGERVDALALIVHKDNAPYRGRELVEKMKELIPRQQFDIAIQAAIGNHIIARSTVKQLRKNVLAKCYGGDVSRKKKLLQKQKEGKKRMKQLGNVEVPQEAFLAILHVGKDSK",
    "output": "Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQAINPIWAEVQKSLQKTLSKPSFETWIRPAKFNCFENGLLTLIAPNTFSSDWLRKNYCETIEKTAKEICGYDVKVIFKSETNINSYLTNKENLDEKKVDHKTKSFSNNSQDISSKNRSKKPNGLNLRYVFKRFVVGPNSRLAHAAALAVAESPGREFNPLFICGGVGLGKTHLMQAIGHYRVEIDPEAKVKYVSTETFTNDVISGIRRDGMTAIRDKYRNVDLILIDDIQFLEGKEYTQEEFFHTFNALHESGSQIVIASDRPPNQLSGIQERLISRFSMGMTADIQPPDLETRTAILQKKAEQERMNLPRDLIQFIAGRFTSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNSVGVVVTPKQVINKVSDFFKVSTDELISSSRRKPVSQARQIGMYLMRQGTDLSLPRIGDEFGGKDHTTVMYAIEQVEKKLSIDPNIASQVQKIRDLLQIDSRKNL",
    "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQLPISQYNELLQKKLEKLTALLRPFNAPDIQVFDSPTSHYRMRAEFRIWHEQDDFYHIMFDQATLQRYRVDEFPIASTQINRMMQTLLPLLKQQEVLHKKLFQIDYLSTLSNKIIVSLLYHKTLTEEWESAAKNLKDLLEKQGFNVQIIGRASKQKICFEQDYVDEVLPVNGRNYVYRQVENSFTQPNATVNCKMLEWAIDCTQNSEGDLLELYCGNGNFSIALAQNFRKVLATEIAKPSVAAAQFNIAENKVDNLQIIRMSAEEFTQAMNGVRAFNRLKGIDLKSYECNTIFVDPPRAGLDPDTVKLVQNYDRILYISCNPHTLCDNLVELSKTHRIEKAALFDQFPYTDHMESGVWLIRK",
    "output": "Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKVQAYVSDEIVYKINKIVERRRAEGAKSTDVSFSSISTMLLELGLRVYEAQMERKESAFNQAEFNKVLLECAVKTQSTVAKILGIESLSPHVSGNPKFEYANMVEDIRDKVSSEMERFFPENDEE",
    "output": "Conjugative DNA transfer (CDT) is the unidirectional transfer of ssDNA plasmid from a donor to a recipient cell. It is the central mechanism by which antibiotic resistance and virulence factors are propagated in bacterial populations. Part of the relaxosome, which facilitates a site- and strand-specific cut in the origin of transfer by TraI, at the nic site. Probably autoregulates its own expression. Plasmid specificity is conferred by the TraD-TraM pair (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQVILLDKVANLGSLGDQVNVKAGYARNFLVPKGKAVPATKKNVEYFEARRAELEAKLADVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVDVAKSEVRLPNGVLRTTGEHEVNFQVHSEVFAKVIINVVAE",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAESVERLLQRVEELEQELARERSRRIAGDGHCGRTRIQKMSDEVVDSNPYSRLMALKRMGVVSDYEKIRTYAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQPYQAGMSKVQAAEHTLRSINPDVLFEVHNYNITTVEHFEHFMNRISNGGLEEGQPVDLVLSCVDNFEARMAINTACNELGQTWMESGVSENAVSGHIQLMVPGESACFACAPPLVVASNIDEKTLKREGVCAASLPTTMGVVAGILVQNVLKFLLKFGTVSFYLGYNAMQDFFPTMFMKPNPQCDDKNCRKQQEEYKKRAPAQPTQETAPQEEEEVVHEDNEWGIELVSEVSEEELKNSSGPVPTLPEGITVAYTVPKKREDSVSEVTVEDSGESLEDLMARMKKM",
    "output": "E1-like enzyme which specifically catalyzes the first step in ufmylation. Activates UFM1 by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a UFM1-E1 thioester and free AMP. Activates UFM1 via a trans-binding mechanism, in which UFM1 interacts with distinct sites in both subunits of the UBA5 homodimer. Trans-binding also promotes stabilization of the UBA5 homodimer, and enhances ATP-binding. Transfer of UFM1 from UBA5 to the E2-like enzyme UFC1 also takes place using a trans mechanism. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress (By similarity). Ufmylation is essential for erythroid differentiation of both megakaryocytes and erythrocytes (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSALQALSTSRLDGKVALVTGSGRGIGAAIATELANRGASVVVNYANSPDAAQTVVDAIKKNGGDAIALQADVSDVKQTIKLFDDAVAHYGQLDIAVSNSGVVSFGHLKDVTEEEFDRVFAINTRGQFFVAREAYKHLSVGGRIILMGSITGQAKGVPKHTVYSGTKGAIETFVRCMAIDCGDKRITVNCVAPGGIKTDMYHAVCKEYIPNGENLTNEQVDEYAATWSPLNRVGQPIDVARVCGFLASQDGEWINGKVLGIDGAACM",
    "output": "Reductase; part of the gene cluster that mediates the biosynthesis of elsinochromes, pigments consisting of at least four interconvertible tautomers (A, B, C and D) that have a core phenolic quinone to which various side chains are attached and which play an important role in fungal pathogenesis . The non-reducing polyketide synthase PKS1 was proposed to iteratively catalyze decarboxylation between acetyl-CoA and malonyl-CoA subunits for polyketide chain elongation. The released polyketide undergoes cyclization to form an aromatic ring, and proceeds via serial modification steps to produce the heptaketide back- bone of elsinochrome. As elsinochrome has a symmetrical structure, two identical heptaketides are fused to form a core 1,2-dihydrobenzo-perylene ring structure, which can then be successively modified to produce the various derivatives of elsinochrome. Some of these reactions may be cooperatively carried out, at least in part, by the products of RDT1, OXR1 and PKS1. PRF1, embedded within the elsinochrome cluster possibly functions to stabilize some of the biosynthetic enzymes required for elsinochrome production. As prefoldin is a hexamer containing 2 a and 4 b subunits, additional prefoldin subunits, whose coding genes may not immediately link to the elsinochrome biosynthetic gene cluster, are required to fulfill the chaperone function. In addition, no methyltransferase-coding gene exists within the biosynthetic gene cluster, even though elsinochrome has four methyl groups at positions C3, C7, C8 and C12. Apparently, the identified gene cluster does not contain the entire entourage of genes responsible for elsinochrome biosynthesis. Once elsinochrome is synthesized, it must be exported outside the fungal cells, which is probably accomplished by the ECT1 transporter, to avoid toxicity ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIRWNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK",
    "output": "Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLLPRDLLLLPWRRATAAGEAIARRLNHHRAPPFSDPDDDPPFTRLAERPPRAPSKKKKKEEEDQGGRIRPPEPASSDLPFDFRYSYSETDPAWRPIGFREPTRFSPFGPGRLDRPWDGVAAAAARGEGAGAAATSREEVLGEPLAEEEVAQLVERYRHSDCSRQINLGKGGVTHNMIDDIHNHWKRAEAVRIKCLGVPTLDMDNICFHLEDKTGGKVIYRNINILILYRGRNYDPKQRPQIPLMLWKPLAPIYPRLVQNVADGLTFEKTKELRNTGLNSSPLMKLTRNGVYVNVVDRVREAFKTVEVVRLDCSHVGSSDCKKIGVKLRDLVPCVPLLFKDEQIILWRGKVKQENSVSLQFSPEPS",
    "output": "May be involved in the splicing of group IIB introns in mitochondria."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVPYEYYVVLSGLLMVLGLIGIIIRKNLIAMLLSTELMLNAVNIAFVAFDMKLYDVSGQVFVFFILTIAAAEAAVGLGLIMAIYRLRKDVDVNTLTELKL",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNWITNYVRPKINSMLGRRTDMPENLWIKDPETGEMVFHKDLESNQFVIPSSGHHMKISAKERLKYFLDDGRYEQLENPKVVLDPLKFRDEKRYTDRLKDAKAKTGLEDAIVNALGTIEGLPVVVTVQDFAFMGGSLGMAAGDAIVHAFEVALQRKRPLILFAASGGARMQEGILSLMQLPRTTVGVDRLKEAGLPYIVVLTNPTTGGVTASYAMLGDVHIAEPGALIGFAGPRVIEQTIREKLPDGFQRSEYLMEHGMVDMVVSRLEMRQTIARLLKMLLKMPGEQKPLEPEILPPAVVAAEARPQA",
    "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAIMSDKWIKEAVINHSMIRPFAEKQVRVHNKEKIISYGLSSYGYDARVSNEFKIFTNINSTTVDPKNFSEYNLVDREVDVCIIPPNSFALGRTIEYFKIPRDVLVICVGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGACQFLFLKSDQICDTSYADRQGKYMKQVGVTLPLT",
    "output": "Catalyzes the deamination of dCTP to dUTP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRIVFMGTPSFAEVILRALVENEDKKIEVVGLFTQRDKPFGRKKELKAPETKTYILENHLNIPIFQPQSLKEPEVQILKGLKPDFIVVVAYGKILPKEVLTIAPCINLHASLLPKYRGASPIHEMILNDDRIYGISTMLMDLELDSGDILESASFLREDYLDLDALSLKLARMGATLLLSTLKNFHSITRKPQDHMQASFCKKIAKADGLVGFKDAKNLFLKSLAFKSWPEIFLENSLKLLEVELVENEKSHKEGEILAIDERGVLVGCLKGSVRIARLQAVGKKPLKAKDYLNGRRLKVGGILT",
    "output": "Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVPVSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEDDAPVIYGLEFQARALTAQTAETDAIRFLVGTQSLKFDNQIHIIDFDDENNMINKSVLLHDAGEIWHISGSPADKAVLTTCYNKTSESRVLTCAAVWRMPPEWESGNHESPDDSSNNPQTLELLCHLDNSAHGSMACVLWEPMGDGKRVISLAENHVLLWDLQESSAKATISSSATLEGKGQLKFTAGKWSPHHNCTQLATANDTAIRGWDLRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDVRHISEPVKCLEEHSHWVWSVRYNHSHDQLLLTASSDSRVILSNMVSISSEPFGHLVDDDDLSDPEENQQEDKGKEPLQDSIISTYEEHEDSVYAVEWSAADPWLFASLSYDGRLVINRVPRALKYRILL",
    "output": "May act as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIRVILTDIEGTTSSISFVHDVLFPYASEHLPEFIRANHHTLPAVAEQLVRVAEISGTDRKDIDGLINVLQEWIAEDRKEGALKALQGMVWEQGYHSGELKGHIYPDAADYLKRWHDRGLRLFVYSSGSVKAQKLIFGHSNEGDFTVFFSGYFDTAVGGKKESQSYRNILAELGVDAGTVLFLSDVEEELRAAEEAGLKTAWLVREGELPDTARVVARDFSEVDALLRKR",
    "output": "Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKTISVVTLLCVLPAVVYSTCTVPTMNNAKLTSTETSFNDKQKVTFTCDQGYHSSDPNAVCETDKWKYENPCKKMCTVSDYISELYNKPLYEVNSTMTLSCNGETKYFRCEEKNGNTSWNDTVTCPNAECQPLQLEHGSCQPVKEKYSFGEYMTINCDVGYEVIGASYISCTANSWNVIPSCQQKCDMPSLSNGLISGSTFSIGGVIHLSCKSGFILTGSPSSTCIDGKWNPVLPICVRTNEEFDPVDDGPDDETDLSKLSKDVVQYEQEIESLEATYHIIMVALTIMGVIFLISVIVLVCSCDKNNDQYKFHKLLP",
    "output": "Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells. Participates also in wrapping mature virions (MV) to form enveloped virions (EV)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKYNIVFLFAIIASLACLQLTFAAPAASPLANPGASPDAAPNADPLADPFLPIIGKLLSGLLGKK",
    "output": "Induces chemotaxis. Shows antimicrobial activity against the Gram-negative bacteria E.coli ATCC 25922 (MIC=30 ug/ml), the Gram-positive bacteria S.aureus ATCC 2592 (MIC=5 ug/ml) and the fungus C.albicans ATCC 2002 (MIC=25 ug/ml)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MASEAPHASAPDCAPASSDIPQQDGGSTNGHGHDLKGHGFFALALGSVGVVFGDIGTSPLYAFKEALAAASHDGVTRSEIFGVVSLALWALILIVTIKYVVFIMRADNKGEGGVLSLMALAQHAMGKRTTLVFVLGVAGAALFYGDAVITPAMSVLSAVEGLRTIPALEHGVTNEVVLLIATVMLLGLFFIQSRGTASVGKLFGPVCAVWFGVMFSLGLMNLAANPGILMAISPYYAVEFLAEHGLTGFIVLGAVFLTVTGVEALTADMGHFGRWPIQAAWLFFVLPCLAMNYLGQGAFALTTLETAQAAGKAMPELNWFFEMAPEALRLPLVLLAGAATVIASQAVITGAFSLTQQAIQLGLLPRLDVRRTSETQSGQIFVPQLNTMLLLGVLAIMFTFQTSSALAHAYGLAVTGTMIVTTCMAFIVMRKLWKWSMPMALLFLVPFLALDITFLSANALRFFSGGWLPVLIGAALFTIMATWVRGSQILTDKTRRDSLPVADLMDILRARAPHRAPGTAIFLTSDPDMTPVALMHNLKHNKVLHERNVILTVRTAETPRVSEEERVKIEKVNDDFKKVVVNYGFMESPNIPKALAVCRKQGLKFDIMATSFFLGRRSIVPSANSGMPLWQDRLFIYLMRNAANPTDFFKIPPGRVVELGAQVTV",
    "output": "Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSRLQTRFAQLKQENRAALVTFVTAGDPDYASSLEILKGLPAAGADVIELGMPFTDPMADGPAIQLANIRALDGGQTLARTLQMVREFRSGDSETPLVLMGYFNPIHHYGVERFIAEAKEVGVDGLIVVDLPPEHNEDLCHPAQAAGIDFIRLTTPTTGDQRLPTVLEGSSGFVYYVSVAGVTGANAATLEHVEEAVARLRRHTDLPIGIGFGIRSAEHAAAVARLADGVVVGSALIDRIAKARDNAQAVKDVLALCGELAEGVRNAR",
    "output": "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPVITLPNGSKREFSNPITVLDVAADIGPGLAKATLAGIVDGKEVDAGFTIEQDAALSIVTEKSPEGLEVIRHSTAHLLAQAVKSLFPEAQVTIGPVIDDGFYYDFAYSRAFTPEDLAAIEKKMTELSEQDIPVSRRVLPRDEAVAFFRGIGEDYKAEIIESIPANEDLSLYKQGDFEDLCRGPHVPSTGKLKYFKLMKVAGAYWRGDAKNEMLQRIYGTAWANKKDLKAYLHRLEEAEKRDHRKLGKKFDLFHLQEEAPGMVFWHPKGWSVYTAIEQYMRKVQRENGYKEIKTPQVVDRSLWERSGHWDKFRDGMFTVESESRDYAVKPMNCPCHIQVFNQGLKSYRDLPLRFAEFGSCHRNEASGTLQGIMRVRAFTQDDGHIFCAEDAIQSEVSIFTDLLYEVYRDFGFEDVIIRLSTRPEQRVGSEEVWDKSEKALADALNAKGLAFEYLPGEGAFYGPKIEFSLKDCIGRVWQCGTIQVDFSMPARLDAQFVAEDGSRQVPVMLHRAILGSFERFIGILIENYEGAFPPWLAPEQVVVMNITDNQAEYAEKVRNSLQNEGFRVVSDLRNEKIGFKIREHTIQKVPYLLVVGDQEMENNSVAVRTREGKDLGTYSVDDFATLLADSVAKRGRA",
    "output": "Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVHFSDSLSRLLAELQKLPGVGEKTALRLAFHLLKSPDNAAALADSLRDVMSRVRFCSVCFGITEDDPCRFCSDARDDGAICVVEEPQDLLAVERTRAFRGRYHVLQGALSPLNGVTPDRLRVAELMKRLEGGGVREVVIATNFTVEGEATALYLARMIKPLGVRVTRLAHGIPLGSDLEFVDAATVQRALEGRSEL",
    "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNIKIVCVGKLKEKYFKDGIAEYVKRMGRFAKVKIIQVPDEKAPEKLSPAEMEQVKEIEGKRILDKIKDKEYVYVTAIKGKERTSEDFAKELADLTTYGHSDITFVIGGSLGTSNAVNKRADDLISFGKFTMPHQLMRLVLVEQIYRAFMINSGSPYHK",
    "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSASVAAPPPALSRKAEFKAAKAELLARFQTATNVTPLMHALSRATDDALRRLWHECGLPATLALVAVGGFGRGELSPHSDVDILVLLPDAHARELDERIERFIGMAWDLGLEIGSSVRTVDQCIEEASQDVTVQTSLLEARRIVGSTALFERFMLRYREALDARAFFQAKVLEMRQRHAKFQDTPYSLEPNVKESPGGLRDLQTILWIARAAGFGSSWRELDTRGLITDREARELRRNEGFLKTLRARLHVIAGRRQDILVFDLQTQAAESFGYRPTPAKRASEQLMRRYYWAAKAVTQLATILIQNIEAQLFPATSGVTRVLSPGRFVEKQGMLEIAADDVFERHPDAILEAFLLYEATRGVKGLSARTLRALYNSRDVMNNAWRRDPRNRHTFMQILQQPEGITHAFRLMNQTSVLGRYLLNFRRIVGQMQHDLYHVYTVDQHILMVLRNIRRFAVAEHAHEYPFCSQLIVNFERPWVLYVAALFHDIAKGRGGDHSALGMTDARRFCREHGIEGGDAALVVWLVQHHLTMSQVAQKQDTSDPEVIKRFADLVGNERRLTALYLLTVADIRGTSPKVWNTWKGKLLEDLYRATLAVLGGAQPDAHSELKTRQEEALALLRLETVPPDAHRALWDQLDVGYFLRHDAADIAWQTRVLYRHVAADTAIVRARPSPVGDALQVLVYVKDRSDLFAGICAYFDRNGLSVLDARVNTTRHGYALDNFIVTQTERDVQYRDIANLVEQQLAARLAESAPLPEPSKGRLSRLSRTFPITPRVDLRADERGQYYILSVSANDRPGLLYSIARVLAEHRVGVHAARINTLGERVEDVFMLDGTGLSDNRLQIQVETELLRAIAV",
    "output": "Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQVIKKVEELMGDAKWLVFQEEYNNKLNGKYETLFTLTNGYMGIRGTFEEGSEGERPGSFIAGIFNRGEAQVRELVNVQNWMRLKIYIEGEEIRLDRCELLEFQRILDMKKGVLFRKTVVKDDKGRVTKIEGYRFVSRSNRHRSAIRFFITPLNYEGVIGVENLIEGTVLNSATHPKYRVKHLKVVKNESICKSGIYLETATTDENKRIAVGSTLRIYNLEDINRENIAFFRRFIPLGENSAEYLEFKGEREKTVVVDKFAVTYTSRDVEKDLLKNAVENDLFDFVSRGFDEELEKHIAEYDKLWSVADITIEGDEEADIALRFNIFHLMSSVNEKDPWVSIGAKGLHGEGYKGHVFWDTEIFMLPFFIYVYPEAARTLLMYRYNMLDAARRNAALNGYKGAQYPWESADTGMEETPKWGFDYKGNPVRIWTGDLEHHITADVAFAVWEYFRATNDIDFMLNFGAEIILETARFWASRCEYVEELDRYEINNVIGPDEFHEHVNNNAYTNYFAKWNIKKGLEIIGELKENYPDYYYAITHKISLTPEEVEKWKEVEKKIYIPYDKDKKLIEQFEGYFEKKDYVIEKFDENNMPVWPEGVDVTKLGDTQLIKQADVVMLMLLMPEEFDEETKRINYEYYEKRTMHKSSLSPSMYAIMGLKVGDHRNAYQSFIRSAKVDLADNQGNAVEGIHAASCGGTWQVAVFGFGGLEIDREGVLNINPWLPEKWEKLSYKIFWKGSLLEVTVAKEEVSVKKLKGRETVKIKVKGKEMAL",
    "output": "Hydrolyzes kojibiose in the presence of an inorganic phosphoric acid to form D-glucose and beta-D-glucose-1-phosphoric acid."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEHYISLFVKSVFIENMALSFFLGMCTFLAVSKKVSTSFGLGIAVIVVLGIAVPVNQLVYTHILKENALVDGVDLSFLNFITFIGVIAALVQILEMFLDKFVPSLYSALGIFLPLITVNCAIFGGVSFMVQREYNFTESVVYGIGAGTGWMLAIVALAGLTEKMKYADVPAGLRGLGITFITVGLMALGFMSFSGIQL",
    "output": "NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKHRPVHERQCSTETKNWKENTQLIMQSSSGHTHHQPGSNDSPSVCMSLPVPQLSAEGSCTAGDVTIDLSSPESHHGARSSSRRVRPGNGRSLSRHGHTHSHDANGPEDANDADSREQSNSISEVFHFYKWLEKSFPYILIFSAKLVVQHITGISVGIGLLTTFLYANKCIVNQVFLRDKCSKLQCLWILVFLLFSSLLLYYTFSSQALYYSLVFMNPSLGPLHFFDALWVVGITDFIGKFFFMGLKCIILLVPSFVMSHKSKGYWYMALEEVAQCYCMLVSTPVWFRYLIDYGNQNSGAEWHFGILLALLYLILKLLIIFGQRKTSSNSLRLFLTQPNYGAAATKSQCSEVDGMCAICQAEFIKPIVLVCQHVFCEECISLWFNKEKTCPLCRTVISNQSHKWKDGATSLQLRIF",
    "output": "E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAQETLVDTSIQGKIVQCIGAVVDVEFARNQMPKIYDALKMEGSSLTLEVQQQLGDGIVRTIALGTSDGLRRGNIVYNTGANITVPVGKATLGRIMDVLGAPIDERGPVDQTLTAPIHRKAPAYDELSPSQELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMADSGVVNLDKLEDSKVAMVYGQMNEPPGNRLRVALTGLTIAESFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGSITSIQAVYVPADDLTDPSPATTFAHLDSTVVLSRDIASLGIYPAVDPLDSTSRQLSPAVVGEDHYNTARAVQGTLQRYKELRDIIAILGMDELAPEDKLAVARARKIQRFLSQPFHVAEVFTGSPGKYVSLAETIRGFKMIVAGECDHLPEQAFYMVGTIDEAFEKAKKM",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "VRDGYIADDKDCAYFCGRNAYCDEECKKGAESGKCWYAGQYGNACWCYKLPDWVPIKQKVSGKCN",
    "output": "Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. Has paralytic activity in mice."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIEVGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFEYSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF",
    "output": "Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSCLPALDKFLQNYHQSYLSTLGELPRYYPQGEPSLCIQGEFDESSDEAVSWLPVKREQLGSFANVEHALELTLWPDINHFYGEYFAAPVLFDSPWGTGELLQVWNEADFDALQQNIIGHLMMKQKLKQPATWFIGLLDEGDKMLTVDNADGSVWVEIPGELPSTQLAPSLAEFIEALSPRIAPPVKHEELPMPALEHPGIFASFKRMWHNLIGKR",
    "output": "Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKDPIETYMNLVPMVVEQTSRGERAYDIFSRLLKERIIFLNGPVHDGMSSLIVAQLLHLEAENPAKEISMYINSPGGVVTSGLSIYDTMQYIKPKVSTLVIGQAASMGSLLLTAGEAGMRFSLPNSRVMVHQPSGGYQGQATDIMIHAAETQKLKDRLNEIYVKHTGQTMKKVVDALERDNFMSPEEAKEFGLIDEIVENRSKDDAET",
    "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIVAVPNSGASRINQSGVEALREFPNFPIGGILFKDIAPMLAGRGALGEVVSTVASQVSGTEIDAILAVDARGFILGASLADRLGCGFIMVRKPGKLPGDVLSFEYSCEYCSGTLEVTAGLIGDGLRCLIADDLLATGGTARATGNFVKSQGGEIAGYAFILEIEVLKGRRQLDDAPVISAMTC",
    "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKKADNEHLARMRVEYGSVEKDGSADLDVDWLADGWVALLRRWLADAEAAGIAEPNAIVLGTVDAGGRPVTRTVLCKSVDDTGITFFTNYGSAKGEDLASTPYASATFPWFALGRQVHVRGPVTKVSAEETADYWSKRPRGSQLGAWASQQSRPIASRAELLDQLAEVTERFADHDTVPVPPDWGGYRITAEVVEFWQGRESRVHNRIRVHDGRIERLQP",
    "output": "Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLSAASQVLLRSEELLEQGKWLLVNPTDGHVFSALSNPEVYGFHQFFDIYEQSIASAKAQGRDTQHQFVAAYDTDASFDGAVLYLPKAKAHGQMLLANIVACLKPGGTLLVVGENKGGIKSAAKLLTPYSDNVNKIDSARHCAMFAAVVDKPVASFDITKWQDVSEHQVADISFKVCSLPGVFSHGELDTGTQLLLDNIDRVVSGRILDFACGAGIIGCFAGLKNPQAQVVMSDVSALAIYCSQKSAELNGVKAQVIPSNGLGALTGKFAQVFTNPPFHTGIKTDYSVTEGFMQQLKNHLQDRGSLILVANKFLRYADELDKQFKSVQTLTETTKFSVYCCRR",
    "output": "Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVDKIERIKELVEILNKYSYDYYVLDNPSVSDKDYDKKYDELKLLEKETGVVLPYSPTLRIGDIVLDGFNKYTHKGKLWSLDKAQSLDEIKDWHNRNIKFVNDMRAQGEDLPDLKYIATKKFDGLTVNLTYNEEGMLEVSATRGNGEIGENVTAQVKTIKSIPLKLQENHDLFEVHGEAIMTQEAFEKYNSSADSPLKNLRNGAAGALRNLNVKETARRDLSAFFYDVGYKEGYQFKTYLEMMDFIKEKGLPVDDYLKVCVSIEDIKNEIDYIEKIRFDLNYDIDGLVIAIDDIRTRELLGYTVKFPKWAIAYKFEAQEATTKLVDVEWNVGRSGRIGPTAILEPVELAGVTVKRATLNNMDDIKRKGVRIGADVFIRRSNDVIPEIMGTLENTLENSEEIFPPTECPACGSHVVLNGAHYFCENTLSCKPQLVKTIVHYASRDAMNIAGFSEKTAEQLFEKLNIKSISDLYKLKKEDLINLEKFGDKKAENLLNAVEGSKECKLYSFIYALGIPNVGVKTAKDIVNKFKSIDGLKNATFEELVSVQDVGDIVAQDIIEFFKEEKVISTIDELLSLGVNPIFDEVKIVESIFKDKTVVATGTLQNYSRTEIKTKLESLGAKVSGSVSKKTDYVIAGESAGSKLTKAEELGVEVISEEEFEKMLGRES",
    "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSDNLKIGLQYLTPKHALTRLAGKLASAKMGWLTTAVIKWFIKQYNVNMDEAKNPDPEAYSTFNNFFVRELEDGARPINEDDSVISHPADACVSQFGPIMDGKLVQAKGHVYSAQELLGGDEALAAEFMGGEFATLYLSPSDYHRVHMPCDATLRKMIYVPGDLFSVNPLTAENVPNLFARNERVVCIFDTEFGPMAQILVGATIVGSIETTWAETVTPPTGPAVKTWHYPLSGDDMICFKKGEEMGRFKLGSTVINLFAPNSIKFDDSMENGTPTRMGTPFAHIVK",
    "output": "Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGSGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI",
    "output": "Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQGSVTEFLKPRLVDIEQVNSTRAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSSKEGVQEDILEILLNLKGLAVTIEGKDEAMLTLSKSGAGPVIAADITHDGDVTIVNPDHVICHLTGNNDISMRIRVERGRGYVPASARAQTEDDDRPIGRLLVDASFSPVARIAYNVEAARVEQRTDLDKLVIDMTTNGTIDPEEAIRRSATILAEQLDAFVELRDVTEPELKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASLADDL",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MWLERLELQHFRNYNQLDIEFHKGLNVFLGENAQGKTNILESIYVLALTRSHRTRTDKDLLQFQEKELSISGLLHRTSGKVPLDIHLTDKGRVTKVNHLKQAKLSNYIGHMNVVLFAPEDLQLIKGAPALRRKFIDVELGQIKPLYLSDLSNYNHVLKQRNTYLKSTDKIDENFLSVLDQQLAEYGSRVIQHRIDFLKKLEEFGNRKVQEISGNREELTIEYQTSIELTDDVNLIDKFLTELEKSRKRDLFKKNTGVGPHRDDVAFFINGMNAHYASQGQHRSLVLSLKLAEIELMKEVTREYPILLLDDVMSELDNNRQIKLLETITDTIQTFITTTSLDHLHKLPDSLKIFHIESGKVTESE",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSAALVPADDILEPTLQSILDQKSLRWIFVGGKGGVGKTTTSCSLAIQLAKVRKSVLLISTDPAHNLSDAFGQKFGKEARLVDGFDNLSAMEIDPSASMQDLLAAGGEQGEDMGFGLGGMMQDLAFSIPGVDEAMSFAEVLKQVKSLSYEVIVFDTAPTGHTLRFLQFPTVLEKGLAKLSQLSNQFGPMLNSVLGARGGLPGGQNLDEVLSKMESLRETISEVNAQFKDADLTTFVCVCIAEFLSLYETERMIQELTSYQIDTHAIVVNQLLFPGKDSTCEQCKARRKMQKKYLDEIAELYEDFNVVRMPLLVEEVRGKEKLERFSDMLVHPYQPPQE",
    "output": "ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEMASAFTLNVRLDNIAVITIDVPGEKMNTLKAEFASQVRAIIKQLRENKELRGVVFVSAKPDNFIAGADINMIGNCKTAQEAEALARQGQQLMAEIHALPVPVIAAIHGACLGGGLELALACHGRMCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALEMILTGKQLRAKQALKLGLVDDVVPQSILLEAAVELAKQDRPSSRPLPVRERILAGPLGRALLFKMVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGELAMTPQSQALRSIFFASTEVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGLPVRIKDINPQGINHALKYSWDQLEGKVRRRHLKASERDRQLALISGTTDYRGFAHRDLIIEAVFENLELKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSPVEKMPLVEIIPHAGTSAQTIATTVKLAKKQGKTPIVVRDKAGFYVNRILAPYINEAIRMLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVVSSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGTQGQGRLSAPQVAERCVMLMLNEAVRCLDEQVIRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLATQYGSRFTPCERLVEMSKRGESFWKTTATDLQ",
    "output": "Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSIDDLKSKIPDFAKDVRLNLSSMASDETLTPQQKYGLFVACGIASRNADVRKALVAEAAGKVDASVIQAAKAAASIMGMNNVYYRFVHLASNKDYRTMPARLRMNVISNPGVDKIDFELWSLAVSAINGCGMCIDAHEDVLRKANVTAEAIQAAVRFASIIQSAAIALEAADTE",
    "output": "Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNAMSRISRRIFLALALSLAGLAQAQLSIEITGAGANRIPVTIVDFPGDPTAARVVTATVRADLERSGLFKLVDNGTAAFDENAPVNHAEWKGKGADALAAGSIARSTDGRMEARFRLYDTQKGVSLGGAAYVTNNSQLRAAGHRIADFIYEKLTGEKGVFSTRIAYVVKARGQFLLQIADSDGQNAATALSSTEPIISPVWSPDGGRLAYVSFEKKKPVIYVHTLASGQRHIVANFKGSNSAPAWSPDGRKLAVVLSKDGNSQIYSVNADGSGLQRITQSSGIDTEPRYSADGGTIYFTSDRGGSPQVYQVGASGGDAKRVTFEGSYNVSPRPAPDGKSLAFISRREGRFQLAVMDLASRQVQVVSDSNKDESPSFAPNSRMILIATEIGGRGVLSAVSSDGRIKQRLSVAAGDVREPAWGPYYQ",
    "output": "Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSDERYAASDGGGTEVGSGTRGRTTVVTKPATRPQRPTGKRSRQRAANASNTGANVEVEESSTQAAIAKEGKVKKPKKSADRSANPIVFIYNYLKQVVGEMRKVIWPNRKQMLTYTSVVLAFLAFMVALVGLADFGLAKLVLLVFG",
    "output": "Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSDLSHIRNFSIIAHIDHGKSTLADRFIQMCGGLTAREMEAQVLDSMDLERERGITIKAHSVTLHYKAQDGKTYQLNFIDTPGHVDFTYEVSRSLAACEGALLVVDAGQGVEAQSVANCYTAIEQGLEVMPVLNKMDLPQADPDRVKDEIEKIIGIDATDAVACSAKSGMGVDEVLERLVQSIPAPEGEIDAPLQALIIDSWFDNYLGVVSLVRVRQGRVKKGDKILVKSTGKVHLVDSVGVFTPKHTQTADLKAGEVGFIIASIKDIHGAPVGDTLTLSNTPEVEVLPGFKKIQPQVYAGLFPVSSDDFEDFRDALQKLTLNDSSLQYMPESSDALGFGFRCGFLGMLHMEIIQERLEREYDLDLITTAPSVIYELELKTGETITVDNPSKLPDVSAVNDFREPIVTATILVPQEHLGNVITLCIEKRGVQRDMQFLGSQVQVRYDLPMNEVVLDFFDRLKSTSRGYASLDYHFDRYQSANLVKLDVLINGDKVDALALIVHRDNAAYKGRALTEKMKELIPRQMFDVAIQAAIGGQIIARTTVKALRKNVLAKCYGGDVSRKKKLLEKQKAGKKRMKQVGNVEIPQEAFLAVLRLDS",
    "output": "Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "HSEGTFTSDYSKYLDNRRAKDFVQWLMNT",
    "output": "Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIAKGSEPWLFTAASVTALFAILSRATDGLPFLNYIANVGMALTFVMVIFFRDPERKVETSDTYMISPADGTVIDIRDRKICIFMFLQNVHVNRAPISGKISEIIYKKGGYLPAFCKDSERNERNEFIIHSKYGDVRVTQIAGIIARRIVTYSNVNDTVEQGQRIGMIRFGSRVDVTIPHDFDITVEKGERVLAGKTIIATIKNDRDF",
    "output": "Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTHFSELLDEFSQNVLGQLLNDPFLSEKSVSTEVEPSPMSPAPLIQAEHSYSLCEEPRAQSPFTHITTSDSFNDDEVESEKWYLSTDFPSTTIKTEPITDEPPPGLVPSVTLTITAISTPFEKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSDSEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRTLIAEGYPIPTKLPLTKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEEPSSPGSAGELGGWDRGSSLLRVSGLESRPDVDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELDRRVNTTF",
    "output": "Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (By similarity). In a neuroblastoma cell line, protects cells from ER stress-induced death. In vitro activates transcription of target genes via direct binding to the CRE site (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MALRSAQGDGPTSGHWDGGAEKADFNAKRKKKVAEIHQALNSDPTDVAALRRMAISEGGLLTDEIRRKVWPKLLNVNANDPPPISGKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQREGLQEELIDIILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDPTMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHVVRLYDFFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFVQFPPSELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLTKPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP",
    "output": "GTPase-activating protein specific for Rab1 and Rab2 small GTPase families for which it can accelerate the intrinsic GTP hydrolysis rate by more than five orders of magnitude . Involved in maintaining endoplasmic reticulum structure ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRCDATQEKRAHSESGESVFFQKFLETRQILLSGEISKDLAEGIVRQLFVLESLSVSKPIYMYVDSPGGDVDAGYAIFDVIRFVKTPVYTIGMGLVASAGVLVLLAAKKDCRFGLRNSRYLIHQPLSGMRGVATDIEIHARELEKTRSKLNALIASETGVSLDKVAQDTNRDYWLDASQALEYGLISNLIEKRADLPKK",
    "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNSGPLEFTVSANTNPATDAVRESILANPGFGKYYTDHMVSIDYTVDEGWHNAQVIPYGPIQLDPSAIVLHYGQEIFEGLKAYRWADGSIVSFRPEANAARLQSSARRLAIPELPEEVFIESLRQLIAVDEKWVPPAGGEESLYLRPFVIATEPGLGVRPSNEYRYLLIASPAGAYFKGGIKPVSVWLSHEYVRASPGGTGAAKFGGNYAASLLAQAQAAEMGCDQVVWLDAIERRYVEEMGGMNLFFVFGSGGSARLVTPELSGSLLPGITRDSLLQLATDAGFAVEERKIDVDEWQKKAGAGEITEVFACGTAAVITPVSHVKHHDGEFTIADGQPGEITMALRDTLTGIQRGTFADTHGWMARLN",
    "output": "Catalyzes the reversible transfers of an amino group from glutamate to the alpha-ketoacid of the respective amino acid in the final step in the biosynthesis of branchedchain amino acids. The amino acids can be ranked in the following order with respect to their efficiency as amino donor: Leu > Ile > Val."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAITKYKAAAVTSEPGWFDLEGGVRKTIDFINEAGQAGCKFVAFPEVWIPGYPYWMWKVTYLQSLPMLKRYRENSMAVDSEEMRRIRRAARDNQIFVSLGFSEIDHATLYLSQVLIGPDGAVINHRRKIKPTHVEKLVYGDGAGDTFMSVSETEIGRVGQLNCWENMNPFLKSLNVSAGEQVHVAAWPVYPGKERQVYPDPATNYADPASDLVTPEYAIETGTWTLAPFQRLSVEGLKINTPEGVEPETDPSVYNGHARIYRPDGSLVVKPEKDFDGLLFVDIDLNECHLTKVLADFAGHYMRPDLIRLLVDTRRKELITEADPNGSIATYSTRQRLGLDKPLEKKEGEDTPDVL",
    "output": "Catalyzes the hydration of cyanide to formamide. Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASSGPERAEHQIILPESHLSSPLVKHKLLYYWKLTGLPLPDECDFDHLILSRQWKKILESASPDTERMIKLGRAVHQTLNHNSRITGVLHPRCLEELASIEVPDSTNKFRKIEKKIQIHNTRYGELFTRLCTHIEKKLLGSSWSNNVPRSEEFNSIRTDPAFWFHSKWSTAKFAWLHIKQIQRHLIVAARTRSAANKLVMLTHKVGQVFVTPELVIVTHTNENKFTCLTQELVLMYADMMEGRDMVNIISTTAVHLRSLSEKIDDILQLIDALAKDLGNQVYDVVSLMEGFAYGAVQLLEPSGRFAGHFFAFNLQELKDILIGLLPNDIAESVTHAIATVFSGLEQNQAAEMLCLLRLWGHPLLESRIAAKAVRSQMCAPKMVDFDMILQVLSFFKGTIINGYRKKNAGVWPRVKVDTIYGKIIGQLHADSAEISHDIMLREYKSLSALEFEPCIEYDPVTNLSMFLKDKAIAHPNDNWLASFRRNLLSEDQKKHVKEATSTNRLLIEFLESNDFDPYKEMEYLTTLEYLRDDDVAVSYSLKEKEVKVNGRIFAKLTKKLRNCQVMAEGILADQIAPFFQGNGVIQDSISLTKSTLAMSQLSFNSNKKRITDCKERVSSNRNHDPKSKNRRRVATFITTDLQKYCLNWRYQTIKLFAHAINQLMGLPHFFEWIHLRLMDTTMFVGDPFNPPSDPTDCDLSRVPNDDIYIVSARGGIEGLCQKLWTMISIAAIQLAAARSHCRVACMVQGDNQVIAVTREVRSDDSPEMVLTQLHQASDNFFKELIHVNHLIGHNLKDRETIRSDTFFIYSKRIFKDGAILSQVLKNSSKLVMVSGDLSENTVMSCANIASTVARLCENGLPKDFCYYLNYIMSCVQTYFDSEFSYNNNSHPDLNQSWIEDISFVHSYVLTPAQLGGLSNLQYSRLYTRNIGDPGTTAFAEIKRLEAVGLLSPNIMTNILTRPPGNGDWASLCNDPYSFNFETVASPNIVLKKHTQRVLFETCSNPLLSGVHTEDNEAEEKALAEFLLNQEVIHPRVAHAIMEASSVGRRKQIQGLVDTTNTVIKIALTRRPLGIKRLMRIVNYSSMHAMLFRDDVFSSNRSNHPLVSSNMCSLTLADYARNRSWSPLTGGRKILGVSNPDTIELVEGEILSVSGGCTRCDSGDEQFTWFHLPSNIELTDDTSKNPPMRVPYLGSKTQERRAASLAKIAHMSPHVKAALRASSVLIWAYGDNEVNWTAALTIAKSRCNINLEYLRLLSPLPTAGNLQHRLDDGITQMTFTPASLYRCHLTFTYPMILKGYSLKKESKRGMWFINRVMLLGLSLIESIFPMTTTRTYDEITLHLHSKFSCCIREAPVAVPFELLGVAPELRTVTSNKFMYDPSPVSEGDFARLDLAIFKSYELNLESYPTIELMNILSISSGKLIGQSVVSYDEDTSIKNDAIIVYDNTRNWISEAQNSDVVRLFEYAALEVLLDCSYQLYYLRVRGLDNIVLYMGDLYKNMPGILLSNIAATISHPVIHSRLHAVGLVNHNGSHQLADTDFIEMSAKLLVSCTRRVISGLYSGNKYDLLFPSVLDDNLNEKMLQLISRLCCLYTVLFATTREIPKIRGLSAEEKCSVLTEYLLSDAVKPLLSPDQVSSIMSPNIITFPANLYYMSRKSLNLIREREDKDSILALLFPQEPLLEFPSVQDIGARVKDPFTRQPAAFLQELDLSAPARYDAFTLSQIHPELTSPNPEEDYLVRYLFRGIGTASSSWYKASHLLSVPEVRCARHGNSLYLAEGSGAIMSLLELHVPHETIYYNTLFSNEMNPPQRHFGPTPTQFLNSVVYRNLQAEVTCKDGFVQEFRPLWRENTEESDLTSDKAVGYITSAVPYRSVSLLHCDIEIPPGSNQSLLDQLAINLSLIAMHSVREGGVVIIKVLYAMGYYFHLLMNLFAPCSTKGYILSNGYACRGDMECYLVFVMGYLGGPTFVHEVVRMAKTLVQRHGTLLSKSDEITLTRLFTSQRQRVTDILSSPLPRLIKYLRKNIDTALIEAGGQPVRPFCAESLVSTLADITQITQIIASHIDTVIRSVIYMEAEGDLADTVFLFTPYNLSTDGKKRTSLKQCTRQILEVTILGLRVEDLNKIGDVISLVLKGMISMEDLIPLRTYLKHSTCPKYLKAVLGITKLKEMFTDTSVLYLTRAQQKFYMKTIGNAVKGYYSNCDS",
    "output": "RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymerase binds to the genomic RNA at the 3' leader promoter, and transcribes subsequently all viral mRNAs with a decreasing efficiency. The first gene is the most transcribed, and the last the least transcribed. The viral phosphoprotein acts as a processivity factor. Capping is concommitant with initiation of mRNA transcription. Indeed, a GDP polyribonucleotidyl transferase (PRNTase) adds the cap structure when the nascent RNA chain length has reached few nucleotides. Ribose 2'-O methylation of viral mRNA cap precedes and facilitates subsequent guanine-N-7 methylation, both activities being carried by the viral polymerase. Polyadenylation of mRNAs occur by a stuttering mechanism at a slipery stop site present at the end viral genes. After finishing transcription of a mRNA, the polymerase can resume transcription of the downstream gene.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSRRRVIGQAEILREPKFGNLDVAKFMNVVMLSGKKSIAESIVYGAFEAIQNKTGKDPIEIFSQALSNVKPMVEVKSRRVGGANYQVPVEVRPQRRAALAMRWIREAAKKRGEKSMAQRLANELVEASEGRGAAMKRRDEVHRMAEAHKAFSHFRF",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTSFMSRVWCKVESTGRQLPIVLNAVLVFSITAEVSYLVLVEAPFEPEQKKTDWSTIWTGLHLFAQYFMLGNITWNASLFVKTNPSIRGVFLGGDTLGQGWRYCYNCETHTPPRCSHCYDCNVCVLRRDHHCVFFGQCVGFHNYRYFLTCLLFMWAGLLYAVVMNAEVFIFILKEGVTFHSVMLLLVPWIMLVSGQVTTRAFAFAFIADTCVVGFLLVAAFLFFHVALMLRGQTTREWYSTRRPYSLGTMANIRECLGKNWYFCWLCPLIPSPLPGDGINFKVTASLEPKKQAVH",
    "output": "Probable palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVEAEELAQLRLLNLELLRQLWVGQDAVRRSVARAASESSLESSSSYNSETPSTPETSSTSLSTSCPRGRSSVWGPPDACRGDLRDVARSGVASLPPAKCQHQESLGRPRPHSAPSLGTSSLRDPEPSGRLGDPGPQEAQTPRSILAQQSKLSKPRVTFSEESAVPKRSWRLRPYLGYDWIAGSLDTSSSITSQPEAFFSKLQEFRETNKEECICSHPEPQLPGLRESSGSGVEEDHECVYCYRVNRRLFPVPVDPGTPCRLCRTPRDQQGPGTLAQPAHVRVSIPLSILEPPHRYHIHRRKSFDASDTLALPRHCLLGWDIFPPKSEKSSAPRNLDLWSSVSAEAQHQKLSGTSSPFHPASPMQMLPPTPTWSVPQVPRPHVPRQKP",
    "output": "Inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1. Exhibits opposing effects to IGFBP2 on cell invasion."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTMKLIWDKFYVSIIFVLTCIILGIILMCTVVGGGNDYSEVNVSEGDSLWALADQYAGKSDMAKADFVSWVEKENNLADGHVEAGDSVVIPVHKTKLIKSDSTIQLANQ",
    "output": "Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and/or DivIC to the division machinery."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MHEVKQPRRIMVVTGEASGDLHGAHLIEAAGKVDPGLSFFGVGGACMAKAGCEILIPGEDLAVMGLVEVLGHFPTIWRAFRKLKKILHGPQRPDALVLIDFAEFNLLLAAQAKKAGVPVLYYVSPQVWAWRRGRVRRIASVVDRLAAIFPFEPELYQGLDIDVEYVGHPLLDEFAITCERDAFLRRLGLDPARQVIGLFPGSRKNELKYIAETILQSAVKLREKHPDAQFLLPVASSFRRQDIEALVAPYGLPVTVVDEPIYDVINACDAVISVSGTVTLQVALVGTPMAIVYKMAPLSFAIGKRLIRVPHIGLANIVAGRGVVKEFIQEDATPAMISREIDAILTDAEYNRSIRGGLATVQQRMGEGGCAARVARMVSELCREIPGKERMV",
    "output": "Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRHYEIVFIVHPDQSEQVPAMIERYKTTITSHGGQIHRIEDWGRRQLAYMIEKLAKAHYVCMNIECDQATLDELEHAFKFNDAVLRHLIVKMKKAETGPSPMMKEVQREEAKKAAAAQPTEAQA",
    "output": "Binds together with S18 to 16S ribosomal RNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSANMHIFENPSALAEALADDVGARLAAAIAARGTASLAVSGGSTPKAFFRSLSRRELDWSKVTVTLVDERFVPPENDRSNHRLVADNLLKDGAAEARFVPLYQAAETAEAAAAIASGRTASLGAPLDVVVLGMGTDGHTASFFPGGTRLEEALDPTTPRGVITMEAEGAGEPRLTFTFSSLQDAGYLVLHIEGSGKKEVLAQAEASGDEAEMPIRAMLRRAASPLQIYWAP",
    "output": "Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKVAKQYAGAQVYGRLLSYLKPLWKVFALAVLGNVIYALASAAMADATKYIVAAIETPSPEGRLLVPMLIIGIFALRGLGSFCGGYFMARVARGIVHRMRLELFRHLTVLPCRFFDSNSTGHLVSRITYNVDQVTGAATNAITVVLREGFTVIGLMGYMIYVSWKLTLLFLVLGPIIGVLIGYVSKRFRRISRRIQSSMGDVTHVASESIGGYRVMRTFGGEEYEFNRFMKASEYNITQALKMSLTQALSTPIIQLVISVFIALLVWLALSPEVRGNMSTGEFLAYITAATTCAKPIRQLTEVNAVIQRGISAAQDVFMQLDEPVEKDEGSYVADRVQGRLEFKSLGFAYSDEGKPALQEINLVIEPGETVALVGRSGSGKSTLVNLLPRFYDYEQGEILLDGKPLKDFALTSLRRQISIVTQQVVLFNDTVTNNIAYGALADATPEQVREAAKSADALGFIEQLEQGFDTLLGENGTRLSGGQRQRMVIARALLKDSPILILDEATSALDTHAERNIQSALETLMKGRTTLVVAHRLSTIENADKIVVMDQGRIVEVGSHRELIEKDGAYAALHKLQFSEADA",
    "output": "Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEWWASSPLRLWLLLFLLPSAQGRQKESGSKWKVFIDQINRSLENYEPCSSQNCSCYHGVIEEDLTPFRGGISRKMMAEVVRRKLGTHYQITKNRLYRENDCMFPSRCSGVEHFILEVIGRLPDMEMVINVRDYPQVPKWMEPAIPVFSFSKTSEYHDIMYPAWTFWEGGPAVWPIYPTGLGRWDLFREDLVRSAAQWPWKKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAASFRFKHLFLCGSLVFHVGDEWLEFFYPQLKPWVHYIPVKTDLSNVQELLQFVKANDDVAQEIAERGSQFIRNHLQMDDITCYWENLLSEYSKFLSYNVTRRKGYDQIIPKMLKTEL",
    "output": "Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C . Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2 . Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development . Notch glucosylation does not affect Notch ligand binding . Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSLKQHTQTIFRQQFDRESDITIKAPGRVNLIGEHTDYNDGFVLPCAINYETVISCGKRGDRQIRVIAADYENQQDIFSLDAPIVPHPEYRWADYVRGVVKHLQMRNADFGGADLVICGNVPQGAGLSSSASLEVAVGQALQSLYQLPLSGVELALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRTLETRAVPMPENMAVVIINSNIQRGLVDSEYNTRRQQCEAAARFFGVKALRDVEPSLFFSIQDELDPVVAKRARHVISENARTLAAADALAAGNLKLMGQLMQESHISMRDDFEITVPPIDRLVEIVKSVIGDQGGVRMTGGGFGGCIVALMPLELVEQVRTTVAQEYPAHSGGKKETFYVCQASQGAGLC",
    "output": "Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAVVAAAAATGSTTRSGGGGGEGTRSGRKKPPPPPLQERVPLGRRAAWAWRLAGLAVLLLLLALLALRLLRHHGGAGGDGGVWRVALVCEAWFAALCALNVSAKWSPVRFVTRPENLVAEGRTPSTTAAEYGELPAVDMLVTTADPALEPPLVTVNTVLSLLALDYPRAGERLACYVSDDGCSPLTCHALREAAGFAAAWVPFCRRYGVAVRAPFRYFSSSSSPESGGPADRKFLDDWTFMKDEYDKLVRRIKNTDERSLLRHGGGEFFAEFLNVERRNHPTIVKTRVSAVMTNAPIMLNMDCDMFVNNPQAVLHAMCLLLGFDDEASSGFVQAPQRFYDALKDDPFGNQMECFFKRFISGVQGVQGAFYAGTGCFHRRKAVYGVPPNFNGAEREDTIGSSSYKELHTRFGNSEELNESARNIIWDLSSKPMVDISSRIEVAKAVSACNYDIGTCWGQEVGWVYGSLTEDILTGQRIHAMGWRSVLMVTEPPAFMGSAPIGGPACLTQFKRWATGQSEIIISRNNPILATMFKRLKFRQCLAYLIVLGWPLRAPFELCYGLLGPYCILTNQSFLPKASEDGFSVPLALFISYNTYNFMEYMACGLSARAWWNNHRMQRIISVSAWTLAFLTVLLKSLGLSETVFEVTGKDKSMSDDDDNTDGADPGRFTFDSLPVFIPVTALAMLNIVAVTVGACRVAFGTAEGVPCAPGIGEFMCCGWLVLCFFPFVRGIVWGKGSYGIPWSVKLKASLLVAMFVTFCKRN",
    "output": "Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLQPARTKYRKMQKGRMRGKAYRGSDLAQGEYGLQATECGRLTSRQIEAARVAITRYVKRGGKLWIRVFPDKPITKKPAETRMGTGKGNVEFYVAVIKPGRVLYELAGVDDASAKKAFHLAAHKLPVATKMVKRGETL",
    "output": "Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPKYYCEYCDIYLTHSSPVGRRQHNQGRKHISAKIEYFQNLLREEGITPQNFLGFLGNQGYNNTLANPMMNNFMPGNYNAYMKYNPMRNYHHSNRNSNYQHSIGMHNNKYSRAGYVPPGSNKYPNNHFHNNKRINNIPKPYNNYTNKPITNSSYKNDKQDYRNNNESNDNMNSNNFSNYQVNKENANFVNKNNEQPN",
    "output": "Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTAHWDDEDISLLLAEAYRLKFAFADAPNHYKK",
    "output": "May act as a GTPase-activating protein for Rab family protein(s)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEVDINGESRSTLTTLPFPGAEANSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEESKAEAMPSLRSKQLDAGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPYEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMIKEPADTEVLQYQLQHLTLRGDRVFARNNT",
    "output": "Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages . The regulation of macrophage function is, due at least in part, to its ability to inhibit glycolysis . May also play a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B . May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAAAMMNKSVLLNKQCGKPAAVPKVVMSKGGFARTSAVNKNRDMMVWQPFNNKMFETFSFLPPLTDEQISKQVDYILANSWTPCLEFAASDQAYAGNENCIRMGPVASTYQDNRYWTMWKLPMFGCTDGSQVLSEIQACTNAFPDAYIRLVCFDANRQVQISGFLVHRPPSATDYRLPADRQV",
    "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "YYTPDYDTKDTDILAAFRMTPQPGVPPEEAGAAGAAESSTGTWTTVWTDGLTSLDRYKGRCHDIEPVAGEVNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFIGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEALFKAQAETGEIKGHYLNATAGTCEEMLKRAIFARELGAPIVMHDYLTGGFTANTSLAFYCRDNGLLLHIHRAMHAVIDRQRNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGEREVTLGFVDLLRDDYIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNE",
    "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA",
    "output": "Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSRSFFATVLGLALAAMTVMAAPADAKSRIKDIVAFEGVRDNQLIGYGIVVGLNGSGDSLRNAPMTKQSLEAMLERQGVNVRDGNLNTKNTAAVMVTANLPPFSAAGARMDVTVSTLGDAKSLLGGTLLVTALQGADGQTYAVAQGSVQTGSVSAGGASGSSVTKGVPTAGRIAAGGIIEKETGFQMVSMDVLRMTLRNPDFTTSRRIADVINGRFPGCAQAQNPTIVAVRPPAGMDMISFVTAIENLEVEPDAPAKVIIDEVAGVIVMGDDVRISQVAIAQGNLTISVQENPAVSQPTPFSRGGQTVVVPQSAVSIEEEKGKKLLTLGGGASLKSLIGGLNALGVTPRDMISILQAIKASGALQAEIEVM",
    "output": "Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MYPRGVKRSQHDRHKQTAFRTIKRSITHRPTSKFISHFAKNFRGKLAPLKQLDESRLDALSLTELEQLKTIIEEKQQEKRAQNNAITFLPNLPTVPFADTNFSIKSLGLRPYNGDARDPKQRIRDRFPQTHERICLLTNDILETDLLLRYRQCLDSLTREENQQLMGDRIFSLTNSPCLAFTVATVEEACSYFKFHDLHNLPVNPQDLFMYTITVMKFEFFNKLNMAKLTCVFNDNGHGDIEYRKLRQLCGKPVLDREMPNSEFEVQQQTPDSFRHPIQQAMSIVVTFARILRQIKEHIIRTKKPQFIRDFDTERVAERYECGLISRLIGKQFSNHKCDDVSCQNRIERIMAPWKPSLFFCTYFAKDAPKFKLFPNLPHEYRNLSFTCPKVDMEPSCSYSTSRDLPQTSHRSHKNQGTPKVKSKVCVEKPDTSNLTTTKTTTEILIEESMETDNKIPDPRELNFNQAKQDEIVIININENVNSKHESESSVEMDLDLDYEADTCETNLNTYSSDSE",
    "output": "Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPKQKIRIRLKAFDHAILDQSAQKIVETAKRTGAEVSGPIPLPTEKDIITILRAPHKYKDSREQFEIRTHKRLIDILNPTPKTVDALMRLDLPSGVDIEIKL",
    "output": "Involved in the binding of tRNA to the ribosomes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKTRVYELAKELKVTNKDLIDTMARLGIYTRSHMSVLENGEVIKVRNHYRQQWRAAKLARMHREQATLKGEGPVPTRGVPDAPRAEEVPSRQVPAPETGAPAQATGATRQPATGSARPANTDETRVQEHKPATAARQAGDAPAAEGTAAAGQPLDGKELRQAVANGQGTEEPRQQPAATGQRAQGGEAGRGQQSRQKKKRRGEGRSRQDENKGSAREDQANRFATRDKEAAPSAGQQSPAEKGQRRPAHSKPLRIPKPPEAVTKDLPEKRRDRSNARPGAKPAESGRSRKREMENQLEERLMRRDKNKGKAQKHKETPKVVFKITLTGSITVQELAKRIGKTAAEVIKYLMGQGIMATINQELDLETAALVAQDLGAIVEIKAEKPITELEDLVDPPETLRERPPVVTVMGHVDHGKTSLLDAIRRTNVTASEAGGITQHIGAYQVRLKNRKITFLDTPGHAAFTAMRARGAQATDIAILVVAADDGVMPQTIEAINHAKAAGVPIVVAINKIDRPEANPERVKQQLTEYGLVPEEWGGDTIMVPVSAVTKEGINDLLEMVLLTADVAELKANPDRPARGIVIEAKLDRGRGPVATMLVQKGTLKIGDNLVAGSVYGRVRAMIDDRGERVNSAPPSTPVEVLGLSELPEAGDIFQVVEDEKLARQIASSRQEEKRQEELKAASKTTLDDLFKQMEAGEVKELNLVIKGDVQGSVEALRGALEQLSTSEVKVNLLHGGVGAITETDVMLAAASKAIIIGFNVRPEANVRKAAEEAGVEIRLYRVIYEVIDDVKAAMSGLLEPEEREVILGRAEVRATFKVPKAGTVAGCFVTEGKIQNRALARVIRDGVVVFEGRIESLKRFKDDVREVAQGYECGVGLEKFNDIKEGDVIEAYTIEEIQREL",
    "output": "One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "METQLSNGPTCNNTANGPTTVNNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKSRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA",
    "output": "RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs . Seems to recognize a GAAA motif . Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'UTR ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSWHQAVWNEPLIFEYKGKGRIGFKIPEEEELKKEISINIPEKLRRKEIDLPELSELEVIRHFIRLSQMSFGVDNGMVPLGSCTMKYNPKIEEEAELLTQNLHPLQDDSTVQGILEVLYYMQKWLAEITGMDLCSLQVPAGAAGELAGVLMIKKYHETKGRGNRDEMLVADTAHGTNPASASMENFKVIYIKSNSEGLVDVDILKEIVSERTAGFMLTNPNTLGLFEENILDIAKYIHSVDAKLYYDGANLNGILGVVRPGDMGFDIVHLNLHKTFAVPHGGGGPGAGAICAKGEMVNFLPYPLVEKKDGKYSLSYIPKYSIGKIATFYGNVGNVVRAYTYILGLGAEGISMIGKMSTLATNYLISQLKNVRGLELIAPYRPRKHEVVFSAKTLAKETGVTANDVAKALLDRGFYAPTIYFPPNVEEALMIEPTETEPKEVLDSFAIAIKEIINTAYSNPKEILDTPKNTSVKRLDQVIANHPSSVTPTYRVKRLREEGKIGSLK",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEVVIVPDAADAAALVADTIGALLEREPEPVLGLATGSSPLAVYDELAARYERGEVSFANARAFMLDEYVGLPADHPERYRTVIEREFAGRVDFAPGAVQGPDGTAEDVAAACAAYEQAITASGGVDLQILGIGTDGHIAFNEPGSSLASRTRIKTLTEQTRRDNARFFGGDVDAVPTHCLTQGLATIMAAKHIVLLASGRGKAEAIHHLVEGAVSAMWPATILQHHPHVSVLVDPAAASRLQLADYYRQTYAAKPDWQGL",
    "output": "Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MELKEKRVFVAGLGVSGVALCRVLVNLGANVIAYDRKNEIALKEALEELKDLPVEIKLGEFKEEFLKGIELVVLSPGISLESEIVKKAKDMGLEILGEVELAYRLSKAPIYAITGTNGKTTTTSLLGEMFRNAGRKVYVAGNIGYPLIYAALEAGPNDHIVAEISSFQLETVKEFRPKISCIINITPDHLDRHKTFENYANIKGRIFENQREEEYVVLNYDDPVTWGLKERAKAKVFPFSRKKVLENGAYVKEGFLYLQNKKVIKVEDIYIPGEHNLENALAASSVAYLSGIEVDAIETTLRTFKGVEHRIEFVAEIEGIKFYNDSKGTNPDASIKAIQALKTPIVLIAGGYDKGSEFDEFVKTFDKKVRKLILIGQTAQKIKKTALKYSYPEEDIFLVDSLEEAVRKAYEVAEKGDSVLLSPACASWDMFKNFEERGKAFKKAVMDLRR",
    "output": "Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDNFLKQISSNVKKPIAELEDPDAVIKFHYMNISFNFPDLYYCNNNLFDKPENNLLDISKSLLMLNSFSHECFILQDILRVIRRYGHVYDVYFLPIGWLVGHGEAPKYHASIKLIRSNTQEIIDGIIRRQLSQYGIQGDNLSIFVDSSNEVAINRHSIIGARQLNPICVVSFYPFDPEHKVFFVIYVGRYKDKYCGISYVADREDMYKVINRIYPYVSCFYLVSDGIINFHTTPVANHTRNIKPLPVNYCNTLCEIVYDFEYLKFEQGVMSIPVFMPFVPKQFVSIINLPDDILITCTASSNIEYITHIDNKKLKRILIIIKDKFLKGTIMQGTFKKVNIIRHKKYTYTITYSSFDCPKLEDTKSSLPSTCNKAILDGRRYVTKTFNDTI",
    "output": "Binds to the hairpin form of the viral telomeric sequence. Might direct genome encapsidation into the virus particle (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMSNDRKVTEIENSPVTEVRPEEHAWYPDDSALAAPPAATPAAISDQLPSDRYLNRELSWLDFNARVLALAADKSMPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPREQLGRIGEQTQQLASRHARVFLDSVLPALGEEGIYIVTWADLDQAERDRLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGTQHFARVKVPDNVDRFVELAAREASEEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAFRITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDMTESMLELLLRELDVHPGDVIEVPGLLDLSSLWQIYAVDRPTLKDRTFVPATHPAFAERETPKSIFATLREGDVLVHHPYDSFSTSVQRFIEQAAADPNVLAIKQTLYRTSGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIAWARALEQAGVHVAYGLVGLKTHCKTALVVRREGPTIRRYCHVGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLSYRNLLVAPHGIRAGIIDRVEREVAAHRAEGAHNGKGRIRLKMNALVDEQVIDALYRASRAGVRIEVVVRGICALRPGAQGISENIIVRSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEVMAQVKNPRLTAQLDELFESALDPCTRCWELGPDGQWTASPQEGHSVRDHQESLMERHRSP",
    "output": "Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKILYSLRRFYHVETLFNGTFVLAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVLDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGLGAFLLVLKALYFGGVYDTWAPGGGDVRKITNLTLSPGVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICVLGGIWHILTKPFAWARRAFVWSGEAYLSYSLAALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDLEPVLYMTPLN",
    "output": "One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADAEDIQPLVCDNGTGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVSNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDMKEKLAYIALDYDQEMETAKTSSSVEKSYELPDGQVITIAADRFRCPEVLFQPSFIGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGTTMFPGIADRMRQGNHCLAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWIAKAEYDESGPSIVHRKCF",
    "output": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNLFEKLTNQMKETLDSAASLALHSSNQEISLAHIYWALLSNHQSVLNQALNKMNIDKTALELQARSEVDKLPKSSQVQKENLSISKELSSALNLAQGEAIKNGDSFIAVDMFLIANLKESTFVAIFKPLVDIAEFKKTLLSLRGESKIESQSGDDNLESLSKFGIDLTQKALENTLDPVIGRDDEINAMMQILIRKSKNNPILLGEPGVGKTAVVEGLAQRIVAKAVPTSLQNKKLIALDMSALIAGAKYRGEFEERLKNVVDEVKKAGNIILFIDEIHTIVGAGASEGSMDAANILKPALARGELHTIGATTLKEYRKYFEKDAALTRRFQPINVNEPSINEALQILRGIKPNLEAHHNVNITDAALVAAAKLSSRYITDRFLPDKAIDLIDEAAAELKMQIESEPLELSKIKKHIANLEVEKQALNMEKTNVNEARVLEIDKELENLREEKMSLEGKFEQEKSVFTRIATIKAELDSLKRESELAKRSGDYNKAAEIDYGKIPDIQAQEAALHKQWEEMQQNGTLLKNAVTQESIAGVVSRWSGIPIKKMLQSQKERILGIESELAKSVVGQDDAIKAIARAIKRNKAGLNDASRPIGSFLFLGPTGVGKTQCAKTLAEFLFDNAKSLVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGVLTEAIRRKPYSIVLFDEVEKAHPDVFNILLQVLDDGRLTDSKGVSVDFSNTIIILTSNIASDKIMEIGDKQERQKAVKEALKMYFKPEFLNRLDDVVVFNPLGLADITQIVDIMFKSLAKRALEKGINVTLSQEAREHIAQVGFDSVYGARPLKRALYEEVEDRLADLILRDEIKEGDRVNFALKNGEICTHIEKE",
    "output": "Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGLAQNLEENNVGIIILGPYTEIREGDEVRRTGRIMQVPVGKELIGRVVNPLGQPVDGLGPINTTNTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTAVALDTIINQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPYAGVTMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFIETQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAGTSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGSDLDKATQAKLNRGARTVEVLKQGLHKPLRVEKQVIILYALTRGFLDDIPVVDITRFEEEFHAWLDSNATDLLEEIRTTKKLADDDKFAAAINGFKKVFVASE",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKFIVIEGLEGAGKSTAIKNVLATLAKHGITAPVTTREPGGTPLAEKMRELVKQGHPDEPLTDMAELLLLYAARAQLVGNVIKPALAAGNWVVGDRHDLSSQAYQGGGRGFDRELMATMKRTVLGDFTPDLTIYMDIDPKLGLQRASARGELDRIEQMKLDFFERSRERYLEFANNDESIITIDAGQDLDTVTASIIAALEIWLATNGN",
    "output": "Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKGLVIKNTGSWYQVKTDNGQLVECKIKGNFRLKGIRSTNPVAVGDRVQIILNQEGTAFISEIEDRKNYIIRRSSNLSKQSHILAANLDQCMLVVTVNYPETSTTFIDRFLASAEAYRVPVKILFNKVDAYDEDELHYLDSLITLYTQIGYPCFKISALTGEGVDTIREELKGRVTLFSGHSGVGKSTLINALVPGLEVKTAEISAYHNKGMHTTTFSEMFPVPGDGYIIDTPGIKGFGTFDMEEEEIGHYFPEIFKTSANCKYGNCTHRQEPGCAVRKAVEEHYISESRYTSYLSMLEDKEEGKYRAAY",
    "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVLSAADKGNVKTVFGKIGGHAEEYGAETLQRMFQTFPQTKTYFPHFDLQPGSAQIKAHGKKVAAALVEAANHIDDIAGALSKLSDLHAQKLRVDPVNFKFLGHCFLVVLAIHHPSLLTPEVHASMDKFLCAVATVLTAKYR",
    "output": "Involved in oxygen transport from the lung to the various peripheral tissues."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGTDNHSVRVSVRGIYATALTKRLLDADYEIVQASPVIRERFDIDFDTVYNTVTVTTTDDHQGVGIHGTESAVRSVADVLTSCGRDTLAWDDLTPPGVIFTAQITETQGSGAICALIPAENPDTESKTEPDLNDVHIPDESVATGYLPYDSTDKHIEQGDIMTVQSHRSMPPWDNTDQRADAVVGTTLRANGGLATLIQGHEGVTVDTYDDEDARELAGMIELIDIDLPTGWGIEVNHAATQASLTALKSGLERAIDRAEDISDGAVAEEVTSTGRWLWFGRESRFALDEIRRSVITTIHGHHRIKAAGETASAGVDLAEALCGDIGDGNVQIQHNEFPFEVVTQQFGPTEGERVELYHGKPEGHAFSLGQGEVTDWDANGTIEVTRRISGHGSGTYDELGTPRESGDTAVTRVREGRWWYPTVYRSRDGEHKGTYVNICTPIECFPKSIRYVDLHVDVVKYPDGTVERVDDDELNTAVTAGHIPPALAEKAQSVASSLERALDK",
    "output": "Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFTDMVSKLTSLQQELLSALLDSGVTKDVLVQALEDLCPCPAEFGIKIEKPLSPSSANGGSDCGDSKPVFLTLTGAQGKGGKLSGDEGSEDGDDFDTPPILRELQSLNTEEAAEQRAEVDRMLSEDPWRVARTIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTAKRAALYTWYVQKQREIDRQFDRVQGSDPSDSASQDQVLFFFPEFNHGGHSSGAAGGSGAAVGDEGEPGSKRMRRNRFKWGPASQEILYQAYERQKNPSKEEREALVEECNRAECVQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDTYTPHMNPLLSHTASLSHHHSSESKLRYSQQAASEVTSSTTISHPSVLQQVSPGGLDHCHGLLSTDAKMISVSGGVLPPVSTLTNIHSLSQSSHHHHHHHHQQAQSLIMSLAAQSLTSPQSQSVPVINSVSGLTTLQPMQFPQSSSLTQLTTAHISQQPFAQSHMYSPKQEAGQFSHPSRYSTMDSSTITHLGSSKQCPLQAW",
    "output": "Transcription factor that binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (By similarity). Acts downstream of hnf1ba but is not required for induction of rhombomere r5/r6 gene expression in the hindbrain."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAATMMNKTVVLSKGCTKPSAVPKVSINRKGFLNTAMNKKREMMVWQPFNNKMFETFSYLPPLTDEQISKQVDYILANSWTPCLEFAASDQAYAGNENCIRMGPVASTYQDNRYWTMWKLPMFGCTDGSQVLSEIQACTKAFPDAYIRLVCFDANRQVQISGFLVHRPPSATDYRLPADRQV",
    "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQETFKFLRCNSQGEAVEDKYSLKTLKNHFVVRDEYNNLFRVFSSRDDFWEWEADQPFEQKCFHEVVFGFFPQRLKFDIDFPVNKSYSEEDNDDNVYNILDIIINVIMDVFYETYSLPYNINLTREQILLTDSIGLNKKRELKYSFHIILYTYSVLNNNEAKAFTSKVLENLPKHVYPFVDPQVNKSIQNFRIIGSHKKGSMRVKMFNEELADVFETSMTTKKSDTLITTPFETTCLPCILTHVKEMTNSCDSIQQNELEEVLKFAGVLCKNHCFLRVHKNLVLFKRTSPSYCEICKRMHDKDNTLILRVAGNKVYQHCRHDNKHSLLMGSLSGTTNFVEIYVDQVMTKSIEVHESILFEELPDTQKHIYDESSMREYERVPTLVVKAQMKIGKTIQLRNYLQKYYGNDSISKQQTIRFVTFRQIFSKNIQTRLPNFTLYSEVTGDLDSYERVIIQVESLFRLTSTAEPVDLLILDEVESIFNQFNSGLHKYFAPSFAIFMWMLETANHVICLDANLGNRTYNILQRFRGDVPIFFHWNQYQKAQNDMYYFTSSREIWLNNLLKDLLEDKKIVIPTNSLMEARLLQTFIQKKFPEKKIGFYSSKSTAHERESHFNNVSYYWGLIDILIYTPTISAGVSYEDKRFDVLYGFFNNMSCDVETCCQMLGRVRELKSKTYKICLQGKQNYFPETIEDIETFTLQKRDTLFQTINNHQLSFTYSKETGRPIYYKTPYYHLWLETMRIQHLSKNHFITRFINQVADTGAKVFILTGEKLETVKQYTSIKMEIKHQDYVNIASAETIDANKALLIKQNLKEGITVDQQDLFAYEKYKLLEFYAWHGNKITPKFVEQYNSFMTKQNYTGRVQISRGKTVHESLTMLQTQELNFHQWAMQHAEHHDLQFNYSFQSHMYAIMLLTKCGFKCVQDPNILTNEQLMTKLVDEFVQYDLSAVSFEFKLKKPNKMDPQTILKFINKVLGIRYGLKIHHNKGNYYIKNTKAGSLIPFVRQQIKQSPCVVSNLLPITETFSTKEESSPTREETSSIKEKTFTET",
    "output": "May be involved in DNA replication."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTKFVFVTGGVVSSLGKGIASASLAAILESRGLKVTLIKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFIETRMKQANNFTTGRIYQSVLEKERRGDYLGKTVQVIPHVTNEIQEFIKRGAGIGTPDAVDVAICEVGGTVGDIESLPFLEAVRQLSLKLGPNNSAFVHLTYLPWIAAAGELKTKPTQHTVQKLREIGIQPDALLCRALHAVPEEEKEKISLFTNVAEWGVISMWDVDTIYKVPRMLHEQGLDGLICDKLRLNTPPANLKRWDDLVYETEHPRGEVQIAMVGKYVELSDAYKSVNEALKHAGMQSHVRVKITHLDSETITDDNAAQQLAQYDAILVPGGFGSRGVEGKISTARYAREHKVPYLGICLGMQVATIEYARHVAGLAGANSTEFDAHCKHPVIALITEWKDEDGTIKTRDANSDLGGTMRLGAQSSDVQPGTLAHSIYGDVVTERHRHRYEANVQYLDKLRTAGLVISALTQREHLTEIVELPKSVHPWYIGVQFHPEFKSTPWSGHPLFNAFIKAAVEHQKPAAKA",
    "output": "Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MESQQLSNYSPISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVQYGDFYWVSKRYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSASQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKPISEINLRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSNNETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDPPPEPPTELSDSFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDRYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDTGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSHYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSHLVQELNKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTFKLLTNKWIH",
    "output": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDIFITTSQDSGAFTCIAANAAGEATATVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSEVTTTSALAKWSVSKSTPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHEAPSKMAAAVSNVYSQTNGAQPPPPSSAPAGAPPQGPPKVVVRNELLDFTASLARASDSSSSSSLGSGEAAGLGRAPWRLPPSAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAAAGGVVPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV",
    "output": "Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSRKVLLVGDGAVGSNFANDLLQTTQVDELVICDLNKDRAAGDCLDLEDMTYFTGQTKLRAGDYSDAADADVVVITAGVPRKPGESRLDLIKKNEAILRSIVDPVVASGFSGIFVVSANPVDILTTLTQKLSGFPKKRVIGTGTSLDSARLRVELAKRLQVPIESVNAWVLGEHGDSSFENFSSAVVNGKPLLDYPGMTEAALDEIEAHVREKGSEIIVKKGATYYGVAMMLAKIVTAILENNDLALPLSAPLHGEYGIKDEIYLGTLAIINGQGISHVLELPLNDSELAKMRASAATIKATLDSLG",
    "output": "Catalyzes the conversion of lactate to pyruvate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLNAAGGAGCDPSSPTATSPMRILILLLAAALAGAFTLFAFAPYRLFWLMPLCLAALVELLQREPRRAFWLGYAWGLGAYVSNFRWIYDSLHDVAGLPAWIAAPLVLLLPAYLALYPGLASWLACRIDPRPGVRWLLAFPAAWELGEWLRGWVMTGFPWGAAGYSQITESPLAGYAPLGGIHLVNYLVALSAAALAMLARAGMRQRIGILIAAALAWGSGVWLRDIEWTTPAGKPITVALAQGNIAQELKWSPENLENSLLTYYRQVAMTRADLMILPETALPLFLDDLPSGYLSMMRGEASRAGMALASGIPRRTDDGRGYLNSVVALSDPKMPYYAKDHLVPFGEFVPLPGLIGWIYQHMDMPLSGFTRGGADQPPLTLAGQKVAFNVCYEDSFGEELIGPASRAGMLANVSNLAWFGKSEAMSQHLQLSQARSLETGRYMLRATNNGMTAIIRPDGEISAVAAPFTAQVLTGFAQSRQGLTPYMRFGNLPVVLGCGALLLLALLLGWRRRGQH",
    "output": "Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLDFEKPLFEIKNKIESLKESQEKNDVDLQEEIDMLEASLARETEKVYTNLKPWDRVQLARLQERPTSLDYIPHIFDSFIELHGDRNYRDDPAMIGGIGYLNGQAVTVVGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFSFIDTKGAYPGKAAEERGQSESIARNLVEMASLTVPVISIVIGEGGSGGALGLGITNRILMLENSTYSVISPEGASALLWKDSNLAKIAAETMKITAEDLYELNIADEVIKEPLGGAHHDVETQAQSIKRTFESHLSELNQLTQEELVEDRYQKFRTIGSYTE",
    "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKKIGLFGGTFDPIHNGHLHIARAFADEIGLDAVVFLPTGGPYHKDAASASAADRLAMVELATAEDARFAVSDCDIVREGATYTFDTVQIFRQQFPSAQLWWLMGSDSLMKLHTWKKWQMLVRETNIAVAMRQGDSLHQTPRELHAWLGKSLQDGSVRILSAPMHNVSSTEIRRNLAGQGVSDGIPPAAARYIREHGLYEK",
    "output": "Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLILTRRVGETLMIGDEVSVTVLGVKGNQVRIGVDAPKDIAVHREEIYQRIQHERTIQSQMQHLEQGSFAPSFDDEDYFNR",
    "output": "A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSAVPHATPSPTTIACLLGPTASGKTAAALALAARRPIEIVSVDSALVYRDMDIGTAKPSRDERASVPHHLIDIIDPADAYSAASFRADTLRLIGEIAARGRTPLLAGGTMLYYKALTQGLNDLPGADPDVRATLDAEAERDGWPALHARLAQVDPDTAARLAPNDSQRIQRALEVFMLSGQPMSVLLAAPRRTDDAAAAYRFVPVALEPSDRAVLHKRIAQRFDAMLDAGFIDEVERLRRREDLHPDLPSMRCVGYRQAWEFLDGDTDYRTMRDKGIFATRQLCKRQITWLRAMPERIVVDCIAPDSTARALDALERVLDGRTPG",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDVLYFRELLSGVATNSAYLDGLMKPYLSRLLEELGQVEKAVLRIALFELSKRSDVPYKVAINEAIELAKTFGAEDSHKFVNGVLDKAAPVIRPNKK",
    "output": "Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSAHQKYVRQAWQKADINTKWAATRWAKKIEARERKAKMTDFDRFKVMKAKKMRNRIIKNEVKKLQKAALLKASPKKAPGTKGTAAAAAAAAAAKVPAKKITAASKKAPAQKVPAQKATGQKAAPAPKAQKGQKAPAQKAPAPKASGKKA",
    "output": "Component of the large ribosomal subunit . The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEEVLLKSD",
    "output": "This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTEPTFPRRPQAIFLMGPTASGKTVLAMALHQHLPVEIISVDSALIYRGMDIGTAKPGADELARAPHRLIDIRDPAEAYSAADFRRDALKEMAEITEAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEREAETVGWQALHRQLQQIDPIAANRIHPNDPQRLLRALEVFFVSGNTLTELTKISGEALAYRVHQFAIVPLDRALLHQRIAQRFHQMLAAGFEHEVSTLFARGDLHREMPSIRCVGYRQMWSYLADETDYDDMVFRGICATRQLAKRQMTWLRGWHDVHWLDSDEPAALDRVLQVVSA",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MERDNGTIQAPGLPPTTCVYREDFKRLLLPPVYSVVLVVGLPLNVCVIAQICASRRTLTRSAVYTLNLALADLLYACSLPLLIYNYARGDHWPFGDLACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWVVCGVVWLVVTAQCLPTAVFAATGIQRNRTVCYDLSPPILSTRYLPYGMALTVIGFLLPFTALLACYCRMARRLCRQDGPAGPVAQERRSKAARMAVVVAAVFVISFLPFHITKTAYLAVRSTPGVSCPVLETFAAAYKGTRPFASANSVLDPILFYFTQQKFRRQPHDLLQKLTAKWQRQRV",
    "output": "Receptor for extracellular UTP > ADP = 2-methylthio-ATP > ADP-beta-S > ATP = ATP-gamma-S. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Functionally coupled to phospholipase C."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MECKLVNLSNNDVGTTQLNPLIFSVEQKLSILHDIVRWQLAKRRAGTHKVKGISDVSGTTAKPYSQKRTGRARQGSLRSPQFRGGGVIFGPIVRSHAYSLNKKVRKFGLKVALSLKYLNNQVIILNNLNINVKKTSEMCKYIQNFKFSSFLIVGDYEDSLLRAARNLHYVNLIKPIGLNVFDILNHECIMLTSDALRYLEGRLL",
    "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKGLFIRIVLAICLSLWAIDMVFPWQQIVRSKQNYHTTIQERQKLIVGTINNPVSYFIGTNGETGLEYELSKAFANYLNVDLEMFPLNSADALFQALAQGKIDIAAASLFYQQDRSEKFKLGPAYHAASWQLTYRKGERRPITLENLSGKLVIPANSALNNILLAKKEKYPSLTWETSELSQEELLFQVAEGKIDYTIATSTEVSVNQQIKPQIAIAFNVTDEFTVHWYLSDKGSSELQAALLDFMNSAIENGLIARIEEKYFNHLNQFDYVDTRSYLNAIETVLPKYAPLFEKYKGDLDWRLLAAISYQESHWNPEATSPTGVRGMMMLTKATADRMNITNRLDPEQSIKAGSEYLHLLLKQMPDTILKEDRIWFALAAYNMGLGHLLDVRRLTKQLGGNPDNWLEVKKNLPLLAQKRYFTHLKYGYARGYEAFQYVENIRRYMNSIMNYYRLQQNQQDRQDRYENENNDVISTQTQQEQR",
    "output": "Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPDLPSAFLPLLLLSKFVTPVTFRHHRYDDLVRTLYKVHNQCPDITRLYNIGRSVKGRYLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQGPNMSGYLVGRNNANGVDLNRNFPDLNTYFYYNSKNGGPNHHLPLPDNWKSQVEPETRAVIQWIRSLNFVLSANMHGGAVVANYPYDKSLEHRFRGPHRTSNSPTPDDELFQTLAKVYSYAHGWMHQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPRQEELQREWLGNREALIQFLEQVHQGIKGMVLDENSNNLTGAVISVTGINHDVTSGEHGDYFRLLLPGTYSVTAKAPGYDPKTVTVTVGPAGPTVVDFQLKRSSSQVYPVQRAPGRGQGGRAKQPRTSRKKDPATKRHRGPA",
    "output": "Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSTPTTPPRDAWARLRALTPARIALGRAGTSLPTASHLEFQLAHAQARDAVHLAFDPAPLQAVLQQRGRRSVLLHSAASDRHLYLQRPDLGRRLSDEAAEQLRGTTAVHGGGADLAVVVADGLSALAVHRHAGAMLEQIDALAAHEGWSLAPVTLIAQGRVAIGDEVGELLQARAVIVLIGERPGLSSPDSLGLYLTYAPRVGHTDAARNCISNIRGEGLSYAEAGHKLGYLLREAFRRKLSGVQLKDEADRPLLGTDTASQAAPRNFLLPE",
    "output": "Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRVVFFGTPEFALPSLQILLQPQSPFEVVGLVCQPDRPQGRGQKVLPPPTKILAQAHGIPVWQPGRLRRDPEVLAALEALAADVFVVVAYGQILPPAVLQMPKLGCINVHASLLPAYRGAAPIQWAIANGETETGVTTMLMDEGMDTGAILLQAKLPIEPEQTGLELASQLAQRGAELLVETLVKLEKGELTPIPQDDSRATYAPLLKKQDFQLDWQRPAQALHNQIRAFSPDCFTGLQGQRIKIVRSAAPQLHPPPAELPPGSPGEVVGLARGEGVYVATGEGSLLIRRAQLPGRKEQSACDLVNGGQLRVGMRFEVLPDP",
    "output": "Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDSSVPGGQRTLQKRRNAQLQKEKKANQTPASPRQAGFGGSSSSILKLYTDEANGLRVDPLVVLFLAVAFVFSVVALHVVAKVSGKIF",
    "output": "Necessary for protein translocation in the endoplasmic reticulum."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPQQNLLILYGSQTGTAEDLAGRLSREAKRHHFNCRTEALDEYRVANLINEHLVIFVCATTGQGDPPDNMKNFWRFIFRRNLPHNALCQMDYAVLGLGDSSYPKFNFIAKKLHKRLNQLGACPLLPAALGDDQHELGPDAVVDPWLKDLWSKVLSMFPLRPGLEIISEDVLLPPKYSLRLLEEKVGQSELSGDAYERDFISNNTTPPSEIHPFLAPVLSNERVSAHDHFQDVRLIEFNITGSAIQFYPGDVVMVQPRNSLLHVEQFCSLLHLDPLNKVVVEPSDPESPVPMHLAALCSVQQLVERYLDICSIPRRSFFQLFCHFSPDEMEREKLKEFSCAAGQEELYSYCNRPRRTILEVLVDFPHTTRCIPATFLLELIPQIRPRAFSIASSMEALPNTIQILMAVVQYKTKLIEPRRGLCSTWLASLPPHGTERVPIWVKKGSMKFPCDPDTPVVMVGPGTGVAPFRAAIQERVANGRPGNCLFFGCRGKSKDFYFEKEWEDLGNRGYLTLFTAFSRDQEDKIYVQHRIKENSKLLWDLIGTKQGYVYIAGNAKLMPNEVTDALKWVLQLEGGMSAPDAEQYLASMEKSCRFQSETWS",
    "output": "NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of ciapin1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of cisd1 and activate this protein implicated in Fe/S cluster repair."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSAKIIDGKAIALSVRQRVAARVAERKAKGLRAPGLAVVLVGEDAASQVYVGSKRRACEEVGFISKSYDLAPTITQDELLALIDQLNADPTIDGVLVQLPLPAHLDSTQVIERILPNKDVDGFHPYNVGRLAQRIPALRPCTPKGMMTLLENTGVKIKGMHAVVVGASNIVGRPMTLELLLAGCTTTTCHRFTKGLEQFVRQADILVVAVGKAEFIPGEWIKPGAIVLDVGINRLSNGKLVGDVEYPTAAQHASFITPVPGGVGPMTVATLIENTLQACEQYHS",
    "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDLASLRAQQIELASSVCREDRLDKDPPAFIGGADVGFEQGGEVTRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEQLSQKPDLLFVDGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSAEPGALSPLMDKGEQLAWVWRSKARCNPLFIATGHRVSTDSALAWVQRCMKGYRLPEPTRWADAVASGRPAFVRWQEIQR",
    "output": "DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYFDYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAAKEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGASAVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIEAAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ",
    "output": "Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPKPIFISFEGPEGAGKTSVLEALISELKTKLGDDLVTTREPGGNPISEAIRSILQPEEDNGMDKRTEALLYTAARRQHLVENIKPALDQNKIVISDRYVDSSLAYQGGGRGLGIDNIWEINQFAIDGLLPDMTIYLDVPVEIGLARVNENRQGKIDRLDKESISFHQKVRETYLKLQSEFSDRIKIVDATQPLNKVIDDTRILINQILEDKS",
    "output": "Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLDNTRLRIAIQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYLTLRRLDFGGCRLSLATPVDEAWDGPAALDGKRIATSYPHLLKRYLDQKGVSFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMAQSKQELIDKLLTRIQGVIQARESKYIMMHAPSERLEEVIALLPGAERPTILPLAGEQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME",
    "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTNGKYAARKLKKDRQQRRWSDSEYARRERGLGKKSDPLEGAPQGRGIVLEKVGIEAKQPNSAIRKCVRVQLIKNGKQVTAFCPGDGAISFIDEHDEVTIAGIGGAKGRAMGDLSGVNYKVEKVNGVSLIELVRGNAEKPVR",
    "output": "With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDTSVIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP",
    "output": "Probably mediates the hydrolysis of some nucleoside diphosphate derivatives."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL",
    "output": "Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVRKKIALIGSGMIGGTLAHIIGLKELGDVVLFDISEGMPQGKALDIAESSPIDGFDVHLKGANAYEAIEGADVVIVTAGVARKPGMSRDDLLGINLKVMEQVGAGIKKYAPSAFVICITNPLDAMVWALQKFSGLPVHKVVGMAGILDSARFRYFLSEEFKVSVKDVTAFVLGGHGDSMVPLVRYSTVGGISLPDLVKMGWTTQERIDQIIQRTRDGGAEVISLLKTGSAYYAPAASAVSMAEAYLKGTKRVVPVAAYLSGEYGVNDTYVGVPVVLGSGGVERVIEIDLDKEERDAFDYSVNAVKKLCEACIALVPSLK",
    "output": "Catalyzes the reversible oxidation of malate to oxaloacetate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MANSAQAKKRARQNVKARKHNASLRSMVRTYIKRTLSAIAGGDYAVATEAYKKAVPVIDRMADKGIIHKNKAARHKSRLNAQVKALAN",
    "output": "Binds directly to 16S ribosomal RNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "METIDKIKQQINENPILLYMKGSPKFPSCGFSARAVEAIIQCQVPFGYVDILTNPDIRSELPKFANWPTFPQLWVEGELIGGCDIILEMFQKGELHTLLKETATKHG",
    "output": "Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDYRPSDSSGTDDDLPPSHQGRYQRNARPTGNGRPSVLNSAPLSRVHNEMETQIHLIEQEAYSSILRAFKAQSDAITWEKESLITELRKELRVSDEEHRELLSRVNADEMIRRIREWRKANSLQSSVPQLVHDAPSPAVSGSRKKQKTSQSIASLAMGPPSPSLHPSMQPSSSALRRGGPPPGPKTKKPKTSMQYPSTGIAGRPQAGALTNEPGESGSYDPLVGRKVWTKWPDDNQYYEAVITDYNPVEGRHALVYDINSANETWEWVNLKEISPGDIRWEGEDPGISRKGGHPGQGRGTKTMARGGPASNAGGRGRGSMRMQQPKTQNGIGKKALGEIEILHTETLLKEVEKVFGSVNPNPAEVEKAKRVLRDHELALMDAIAKLEEISDGESGNI",
    "output": "Probably involved in the regulation of chromatin states (Probable). Contributes to basal immunity ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRETSVHIVSLGCPKNLIDSEVMAALLEQAGCRIVSGPEEADILLLNTCAFILPAREESIDEIFRLAEWKKAGKCRHLIVTGCLPQRYGAELAAELPEVDLFLGISEVPNIADHLRVLMEGKHSEKNRVIVTNPLFLMDAGHPRLLSTPPYSAYLKIAEGCSNRCSYCIIPRLRGKARSRPIEDILREAEDLVDRGVRELILVAQDTTAYGRDLEGKPTLALLLRELAGLNTLAWIRILYTYPTGLTDELLNVIANQDRICSYLDVPIQHIDDDILAAMKRRGDSHLIRNSLERARAVIPDLALRTSLITGFPGETPAKFHRLIAFVQETRFDHLGVFPYSPEEGTPAEKLPRQVSQRTKETRRNLLMEEQAVISHEINQTLVGSLQEVLIEGPSSSPDYPMIGRCRRQAPDIDGLTYVKGGKQPFLPGSLVQCRIVAADDYDLFAEVISSPD",
    "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIITLARVDDRLIHGQVTTVWSKESNADRIIIVSSEVYKDDIRKTLLKQAAPPGMKVNIVDVPKAIAVYNNPKYQNEKVFYLFTNPREVVDLVKGGIPLEKLNIGGMQFKQGKTQISKAVSLDADDVAAFRELHQLGVKLDLRVVKTDPSSDILAKIDEVFGKE",
    "output": "The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. The enzyme II SorABCD PTS system is involved in L-sorbose transport."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNVIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEALRWGAEVFHALKKILKERGLETAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENGIMIGFDCASSEFYDAERKVYDYSKFEGEGGAVRTAAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGGRVQLVGDDFFVTNTDYLARGIKEEAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK",
    "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASNLPLQLPAGVSDLLPPEAAALRQLEQRLLNCFRSWGYQEVMTPTFEFATTFQAGSPAGEEGALYKFIDRQGRVLALRPEMTAPIARLVATSLRRRELPLRLGYSARVFRYEEPQAGRRREFHQAGVELIGAGGVAGDVEIIALAVESLAQAGLEDFRLGLGQVAVTKGVLQDLALPPEAVAGIKSALASKDLVALERIYDEYHLEGERRRRLELLATIHGGREALEEARACFGRTAAAASLAELSRVWEALGAAGLEKWLFIDLGILRDFDYYTGIVFEGYVPGLGAPVCGGGRYDGLLAQFGYPCPATGFALGLERLLLARGETAPASLAGGYLVAGRDLAALLKRARELRSKGTAVVLDGESRSRQEAAARAAARGLNLEWIGE",
    "output": "Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MITKQSSNVLRKKRHLRLRKIVSGTSQRPRLNVFRSNKFLYVQIIDDTQQTTLCSANSKESNVLGSNIKAAEAVGALIAKKALAQGIKNVVFDRSGYLYHGKIKALADACRKSGLQF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEVSNSCSSFSSSSVDSTKPSPSESSVNLSLSLTFPSTSPQREARQDWPPIKSRLRDTLKGRRLLRRGDDTSLFVKVYMEGVPIGRKLDLCVFSGYESLLENLSHMFDTSIICGNRDRKHHVLTYEDKDGDWMMVGDIPWDMFLETVRRLKITRPERY",
    "output": "Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSADGRSGRLRFTKMHGAGNDFVVLDLRDGTPPPDAALAAQLADRHFGVGCDQILTIEAPRSEGAVAAYGIWNSDGSAARQCGNGARCVAAWLVRDGTAQGERFIIDSPMSAHAVERLDGDRYAVAMGVPQFEPAQIPLAGFAHARDEYALPVHGETVRFGAVSMGNPHAVVEVGRVDAAPVERVGALLQQNAAFPDSVNVGFVQVVDPAHVRLRVFERGVGETLACGSGACAAAVVLMQRGRVERDVQVSLPGGELRIRWPGDQEQVVMSGPAVFVFDGEWNR",
    "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIDITLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLIPHVQVTSTEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHQLPIAGVVEAVIDGVRDGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHREKITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRALMDFLAQQRIGIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLNTDDPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSDDEKRALREKVAAA",
    "output": "Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAALRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTALHTKLEGFHTQISKYFSERGDAVAKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGETKGMIY",
    "output": "Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTRFQRVAVLGSTGSIGDSTLDVIARHPDRLGVYALSAYSRMDKLAAQAAACGAAVVVVPDDAAAARFRAAWRGKAAMPEVRVGPRALAETAAAPECTTVMAAIVGAAGLPAALAAAQAGKRVLLANKEALVAAGSLFMAAVRENGAELLPIDSEHNAIFQCMPQGARAAAPTAPAPGVRRLLLTASGGPFRRQDPADLHEVTPAQACAHPNWSMGRKISVDSATMLNKGLEVIEAHWLFAMPSERIDVLIHPQSVVHSMVEYDDGSVLAQLGQPDMRTPIAYGLGFPERLASGVGLLDLTRWGRLDFEQPDLQRFPCLALSFAALRAGQPACVALNAANEVAVAAFLEGRLRYTWIARVIEAVLEWQAKQASVTLTSLDDVLDLDARARSFAGNLGLA",
    "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSTAALLTLVRSGGNQVRRRVLLRARGLQDDRWVMPTCHSSTSEPKWSRFDPDGSGRPATWDNFGIWDNRLEEPILLPPSIKYGKPIPKVSLQNVGSASQIGKRKENEDRFGFAQLTNEVLYFAVYDGHGGPAAADFCHTHMEKCILDLLPKEENLETVLTLAFLEIDKTFARHAHLSADATLLTSGTTATVALLRDGIELVIASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSLGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNTTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA",
    "output": "Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDKKQARLRRARKTRARIAELKMARLSVHRTNCHIYAQIIDETGSRVLAQASTLEAEVKKELANGGNAGAAALIGKRIAEKAKAAGVEKVAFDRSGFQYHGRIKALADAARENGLAF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIAGSMVALVTPMDAQGRLDWDSLSKLVDFHLQEGTNAIVAVGTTGESATLDVSEHIEVIRRVVAQVAGRIPVIAGTGANSTREAVELTTNAKTAGADACLLVTPYYNKPTQEGLFQHFSHIANAVDIPQILYNVPGRTACDMLPETVARLSTVKNIIGIKEATGNLQRAKDILASVSSDFLVYSGDDATAVELMLLGGKGNISVTANVAPRLMSDLCAAAMRGDAETARAIHEKLMPLNNTLFIESNPIPVKWALHEMGKMPAGIRLPLTWLSEACHEPLRQALRQSGVLV",
    "output": "Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSEKLLYEALNEGIHEEIERDPKVFVIGEDIGHYGGSYKVTKGLFEKYGNLRILDTPIAENSFTGIAIGAAMTGLRPIIEGMNMGFLLLAFNQIANNAGMLHYTSGGNFTTPLVVRGPGGVGRQLGAEHSQRLESYFQSVPGLQMVACSTPYNAKGLIKSAIRSQNPIIFFEHVLLYNIKENIPQKEYLVPLEKAELVRSGNQITILTYSRMRYHVLQAAKTLIEKGYDPEIIDIISLKPLDMGTISTSLRKTHKVLIVEECMKTGGIGTTLKSAILESLFDFLDTPIMSLSSQDVPTPYNGFLEDLTVIQPSQIVEAAEKIILYS",
    "output": "The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MCRRPDCGFSFSPGPVILLWCCLLLSIVSSAAVNVAPTAAEKVPAECPELTRRCLLGEVFQGDEYESWLRPLVNVTGRDGPLSQLIRYRPVTPEAANSVLLDEAFLDTLALLYNNPDQLRALLTLLSSDTAPRWMTVMRGYSECGDGSPAVYTCVDDLCRGYDLTRLSYGRSIFTEHVLGFELVPPSLFNVVVAIRNEATRTNRAVRLPVSTAAAPEGITLFYGLYNAVKEFCLRHQLDPPLLRHLDKYYAGLPPELKQTRVNLPAHSRYGPQAVDAR",
    "output": "The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH (By similarity). In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA. The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MREILHIQGGQCGNQIGAKFWEVVCAEHGIDSTGRYEGDNVLQLERVNVYYNEASCGRFVPRAVLMDLEPGTMDSLRSGTYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSTVCDIPPTGLKMASTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEDGYEYEDEEEVGEEDA",
    "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD",
    "output": "Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSAFEKPQIISHIQKSLSYTVFDCKWMPCSAKFVTMGNFARGTGVIQLYEIQQGDLKLLREIEKAKPIKCGTFGATSLQQRYLATGDFAGNLHIWNLEAPEVPVYSVKGHKEIINTIDGVGGLGIGEGAPEIVTGSRDGTVKVWDPRQKDDPVANMEPVQGENKRDCWTVAFGNAYNQEERVVCAGYDNGDIKLFDLRNMSLRWETNIKNGVCSLEFDRKDISMNKLVATSLEGKFHVFDMRTQHPTKGFASVSEKAHKSTVWQVRHLPQNREVFLTAGGAGSLHLWKYEYPIQRSKKDSEGVEMGVAGSVSLLQNVTLSTQPVSSLDWSPDKRGLCICSSFDQMVRVLIVTKLHKI",
    "output": "Key assembly factor specifically required for the stability of axonemal dynein heavy chains in cytoplasm."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MISINMTIENAEWGDEKILYTITEKALIATIDRLSLTQVTSELSLLFTNNMRMAQINTQWRNKNKPTNVLSFPAFPLKAGQNPGPMLGDIVLARETIVYEAEEEGKSFHDHLTHMIVHGILHLLGYDHETDDEAYQMEELEKEILQKIAIKNPYTELL",
    "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDAYELVTRNTAEIVTEDELRALLNKPTKRVYTGYEPSGEIHLGHLVTINKLMDMKAAGFDVVVLIANLHAYLNRKGTFEQIKELADYNKACIEAVGLKGAEFVLGTDVQLTPKYQTEVLTLCQQITLNRATRSMDEVGRAMDNPMVSQMVYPVMQVVDIPTLNVDAAVGGIDQRKIHMLAREHLPTLGYKPPVCIHTPIVNGLDGEKMSSSKGNVVSVADSPEEIKKKMKKAFCPPETEGNPILQIFRYNVFPRMDTIAIRRPEKFGGDLEFHSYAELEAAYAGGKIHPMDLKAACGDALTELLADAYAYVQSYKN",
    "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGSEEEVEFKDVPKPKEIREILDEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGSDNKHEDLEKEALLSKVLPEDLLRFGLIPEFIGRLPIIASLEPLDEKALVEILTKPKNALVKQYRKMLELDDVELVFEDEALTEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSREDIEKCVITGKTVTDGEPPRLIMKDGTVVNKDKKTSA",
    "output": "ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLHSSIYWKNLINTFESGCFSIAEVKFIFSNIHIYKNICNPYKNYQLPELARNLQSSKKLDNAILKQDKKNIIDILSPISGIFYSSSKPGASPFVAVGSVVSKGQTLCIIEAMKTMNEIESDSIGKIHQICARNGDFVTKNQVLMKIILEQS",
    "output": "This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRKPCYAVYHPALRLKCLVRKGLGKIKGDTDMCDKQQLKKKEKEKQRAQKVACGPRDPPCTFSRSYTDQKRKEIHLGSTEWGLKESFTLTRGPNRRGNVGKGVKRPMVNKKLGQLELTSLDLRWQKEGKGN",
    "output": "Has a role in meiosis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTEAKPVRVAVVYGGRSSEHSVSCISAGAIMEHLDPEKYEVVPIGITREGTWTQGNRAGLNIVDGRLPEVELHDELALSLNPATRGRIHNVTRHEHYTEVDVIVPVLHGPYGEDGTVQGLFELSGIPYVGAGVLASAVGMDKEFTKKLLVAEGLPVAPQEVLTGEATLDDLQKERLGLPVFVKPARGGSSIGVSKVSAWEDLEAALTLAYESDDKVLIEPEISGAEVEVGVLERPDGSLQASVPAKILGTTESEEGFYDFDAKYIDEGVSAAIPAPLSEELTAELRQRAIEAFRALGASGLSRVDFFVSDYSYCINEVNTFPGFTPISMYPQVFAAVGVGYAELLDTLIQTALARS",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "FNALGLSTRDLVALSGAHTIGQAR",
    "output": "Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRKPVRIGVLGCASFAWRRMLPAMCDVAETEVVAVASRDPAKAERFAARFECEAVLGYQRLLERPDIDAVYVPLPPGMHAEWIGKALEADKHVLAEKPLTTTASDTARLVGLARRKNLLLRENYLFLHHGRHDVVRDLLQSGEIGELREFTAVFGIPPLPDTDIRYRTELGGGALLDIGVYPARAARHFLLGPLTVLGASSHEAQESGVDLSGSVLLQSEGGTVAHLGYGFVHHYRSAYELWGSRGRIVVDRAFTPPAEWQAVIRIERKGVVDELSLPAEDQVRKAVTAFARDIRAGTGVDDPAVAGDSGESMIQQAALVEAIGQARRCGST",
    "output": "Involved in the biosynthesis of forosamine ((4-dimethylamino)-2,3,4,6-tetradeoxy-alpha-D-threo-hexopyranose), a highly deoxygenated sugar component of several bioactive natural products such as the insecticidal spinosyns A and D . Catalyzes the reduction of the C-3 keto moiety of dTDP-3,4-diketo-2,6-dideoxy-alpha-D-glucose to yield dTDP-4-keto-2,6-dideoxy-alpha-D-glucose . NADPH is the better reductant, however NADH can also be used ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARVKRAKNARKNHKKVLKLAKGYYGGKSKLFKTANESVIRALRNSYVGRKNKKRDYRRLWIARINAATRINGLSYSKFMNGIKLAGIDINRKMLSEIAINDAKAFADLVEVAKKQLNA",
    "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKTFTPKPADLTHDWYVIDATDVVLGRLATQAAILLRGKNKPTYAPHADSGNHVIIINADKIALTGNKMGKELYSHSGRPGGLRRDSYAELLEKNPERIIKNAVKGMLPKNRLAKVQLDRLRIFRGAEHPHTPQKPQVFEIAQVSQQAK",
    "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPKTMHFLFRFIVFFYLWGLFTAQRQKKEERTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKGPRSTETFKQIDMDSDRQLSKAEINLYLQREFEKDEKPRDKSYQDAVLEDIFKKNDHDGDGFISPKEYNVYQHDEL",
    "output": "PPIases accelerate the folding of proteins during protein synthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MYEGVQVSSKLEQLQGLLAPVVVALGYQCWGIDFSSQGKHSVLRIYIDKEGGVLVDDCAIVSRQISGVLDVEDPISTEYTLEVSSPGMERPLFTIEQFALYAGEQVRIKLRSPFEGRRNFQGLLRGVEEQDVVVQVEDHEFLLPIDLIDKANIIPTFD",
    "output": "Required for maturation of 30S ribosomal subunits."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "METNLLLVKCVLLASCLIHPRACSPSCNFPAIFNFGDSNSDTGGLSASFGQAPYPNGQTFFHSPSGRFSDGRLIIDFIAEELGLPYLNAFLDSIGSNFSHGANFATAGSTVRPPNATIAQSGVSPISLDVQLVQFSDFITRSQLIRNRGGVFKKLLPKKEYFSQALYTFDIGQNDLTAGLKLNMTSDQIKAYIPDVHDQLSNVIRKVYSKGGRRFWIHNTAPLGCLPYVLDRFPVPASQIDNHGCAIPRNEIARYYNSELKRRVIELRKELSEAAFTYVDIYSIKLTLITQAKKLGFRYPLVACCGHGGKYNFNKLIKCGAKVMIKGKEIVLAKSCNDVSFRVSWDGIHFTETTNSWIFQQINDGAFSDPPLPVKSACTR",
    "output": "Lipase that can hydrolyze p-nitrophenyl butyrate and p-nitrophenyl palmitate in vitro . Possesses low activity against p-nitrophenyl acetate . Substrate preference is p-nitrophenyl palmitate > p-nitrophenyl butyrate >> p-nitrophenyl acetate . Lacks cholinesterase activity ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKRILIVTGQSGSGKSSALQVLEDLGYYCIDNLPLALLPEIVAKLDHENNLEQLALGVDVRSTRADMQEFDLVFEQLQKHGTVDVIYLTTQDQELIARFSASRRPHPLASRFKSLNECIQEEKQLLLPIQFRSTVHIDTTDKSVHDLKHTLLSKLGQSDKLILILQSFGYKHGIPLDADYVFDVRHLPNPHWDLELRRFSGLDEPVRRFLESSDQTNEMFDDIFHFLDKWLPVFAEGHRHYMTVSIGCTGGQHRSVYIVDRLKKALEAKWSIQVLHREMKHWS",
    "output": "Displays ATPase and GTPase activities."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY",
    "output": "Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "WIMGHMVNKIEQINEFLDLGANSIEVDITFDNLGYAEYTYHGFPCDCKRWCTNQENVKEYLNALSDITTPGNPKFRKELTLVVFDLKTGGIDANRMYEGGKDFAGKILFDYWKGSENAGRAYIIISVPSIDHYKFMKGFRERFDGSAFKDLLLEKDGWDFSGNDDLDATRTAYQNAGIEALNHIWQSDGITNCIPRGLGRVNKAVSNRDSPDAFINKVYVWTVEKYSSVKDALNADVDGIMTNHPNVINGVLKEDEFKDRFKLATYGDNPWTKFKR",
    "output": "Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity). This toxin acts on sphingomyelin (SM) (By similarity). It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity). It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity). Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MYAIIETGGKQLKVEEGQEIYIEKLDANEGDTVTFDKVLFVGGETVKIGNPTVEGATVTARVQKHGRQKKIIVFKYKAKKNYRRKQGHRQPYTKVVIEKINA",
    "output": "This protein binds to 23S rRNA in the presence of protein L20."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAVPNRVEAKQMRDHPHRIHEFRLANLVTDPFAISSLSLALIAWIIAFAGSVVAASNSKKYPAFSWWGIVYQILLMVLVLILYCYDLIDYYKSFLSGALAVAFVYTTNSAAEMLYQDGSRMGAASAGVILLSMINIIWMFYFGSDNASPSNRWIDSYSLRGIRHSVLESSIAMSSRPPLVSRNVSKYSASPQMDLYNATPAPHSQGFYPDTHSQHYVSSTALNGFENAGPPTAPALHGNMGHGNNTSTFVTDTTNGNTETTMGDTLGLYSDAGDELTSFPYVAKALYTYTADSNDAYEVSFEQGEMLRVGDIEGRWWKAKRANGETGIIPSNYVELVGENSI",
    "output": "Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIGRIAGTLLEKNPPHILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLLYGFLTPPERSTFRELLKITGVGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKTAERLLLELKGKLGADLGPLAGAASPSDHATDILNALVALGYSEKEALAAIKNVPAGTGVSEGIKLSLKALSKA",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLLVDVATASVDVGAMSSRLAKTARIADLLSRAGTEQDARLVAVTVAWLSGELPQRQIGVGWAALRSLPAPAAAPTLTVTAVDAVFSEIGAVAGKGSQARRAGLIAELFAAATDVEQTFLRRLLTGELRQGALIGVMADAVAKAADVPAARVRRAAMLAGDLPAVAAAVLAGGDAALARFTLQVGRPVGPMLAQTATGVADALDRLGGTAVFEAKLDGARVQIHRRGSDVSVYTRSLDDVTARLPEVVEAALALPVTDLIADAEAIALRPDGRPHRFQVTASRFGRAAARATQPLSVFMFDLLHVDGADLLDQPTSDRVRVLDDLVPAAHRVDRLVTDDGAAAQRFLEATLAAGHEGVMAKSPNAPYEAGRRGAGWLKVKPVHTLDLVVLAVEWGSGRRTGKLSNIHLGARDPATGGFVMLGKTFKGMTDAMLDWQTARFLELADPAAQPATSGRDPTDGHTVKVRPEQVVEIAFDGVQGSTRYPGGMALRFARVLRYRDDKSPAEADTVDTVRAFYEHG",
    "output": "DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK",
    "output": "Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATETERVGAKGGMEHSFGFTRVDETQKQSMVDSVFHSVAENYDKMNDILSLGLHRVWKNSMVAWLSPPALSHWKVLDVAGGTGDIAFRILKASRQKAHATVLDINGSMLSVGKQRAQKNGLAPLIDFVEANAEHLPFEDQSFDAYTIAFGIRNVPHIDQALREAFRVLKPGGRFLCLEFSNVEMPWLDKIYDLWSFHAIPKLGQFIANDGDAYRYLVESIRKFPKQNDFAHMIKQAGFSRVSYRNLTGAIAALHSGWKI",
    "output": "Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKVLIVAKGMGLKSTPSKLNLVADLIRGKDVSVAMMYLKFCRKKSAGYISKVLKSAVANAQANYNIDLDNLYVKEVLVGKSFSLRRIHARARGKACRVYKHYGNVIIKLFERI",
    "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKGYLVAIFLSSIFLYYVLYCILWGTNGYWFPAEEMRTRNNVNNCFKKPAFANLLRFPQLYPFLCRADFIKVAAMSGTNNFPLPYGIKTFETYFSSALSKLQSCDLFDEFDRVPCKRCVVVGNGGVLKNKTLGATIDSYDVIIRMNNGPVLGHEEEVGTRTTFRLFYPESVFSDSSHYDPNTTAVLVVFKPQDLRWLVEILLGKKINTQGFWKTPALKLIYKQYQIRILDPYITSEAAFQMLRFPRVFPKDQKPKHPTTGIIAITMAFHICSEVHLAGFKYNFYSPNSPLHYYGNATMSLMKQNAYHNLTAEQLFLNDIIKKKMVINLT",
    "output": "Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKNFNLLAVSSILLVDLFRTHWGHNVDFSKAINLNGVSFSNVDASSLGAAQVRQSASRGRGLGENPKEEDGADKKKKKDEKQVEPKKPRENKLKQPVENADGNAGGNAGGNAGGNAGGNAGGNADGNAGGNAGGNAGGNAGGNAGGNADGNAGGNADGNAGGNADGNAGGNAGGNAGGNADGNAGGNAGGNAGGNAGGNAGGNAGGNAGGNADGNAGGNAGGNAGGNADGNAGGNAGGNAGGNAGGNAGGTAGGNADGNAGGNAGGNAGGNAGGNAGGNAGGNAGGNAGGNAGGNAGGNAGGNAGGNAGANAGNKKAGDAGAGQGQNNEAANMPNVKLVKEYLDKIRSTISTEWSPCSVTCGKGVRMRKKVSAANKKPEELDVNDLETEVCTMDKCAGIFNVVSNSLRLVILLVLALFN",
    "output": "Essential sporozoite protein (By similarity). In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands (By similarity). In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes (By similarity). Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes (By similarity).; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKPIKIALIGAGNVGNSFLYAAMNQGLASEYGIIDINPDFADGNAFDFEDASASLPFPISVSRYEYKDLKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVDIITRAYRDASGFSDQKVIGSGTVLDTARLQFAIAKRAKVSPNSVQAYVMGEHGDSSFVAYSNIKIAGECFCAYSKLTGIDSSNYEKELEYPVSRRAYEIINRKRATFYGIGAAIAKIVSNIIKDTKNIMIAGANLRGEYGFHGVNIGVPVVLGANGIEKIIEISLNDKEKEKFAKSVAIIDKIYQDAIKNI",
    "output": "Catalyzes the conversion of lactate to pyruvate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPRFVNNDHFRNNHLPNLVKQFEAFGFGTLTIDMVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHDRKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHNLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF",
    "output": "Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLSGILIAALLMTLWGGWQPDIAHASDEFDALRIKWATLLTGGPALDPADSDIAARTDKLAQDANDYWEDMDLSSSRTYIWYALRGNGTSDNVNAVYERLRTMALAATTVGSSLYGNADLKEDILDALDWLYVNSYNSTRSRSAYNWWHWQLGIPMSLNDIAVLLYDDISAARMATYMDTIDYFTPSIGLTGANRAWQAIVVGVRAVIVKDAVKLAAARNGLSGTGIFPYATGGDGFYADGSFVQHTTFAYTGGYGSSVLETTANLMYLLSGSTWSVSDPNQSNVWQWIYEAYRPLLYKGAMMDMVRGREISRSYAQDHAVGHGIVASIVRLAQFAPAPHAAAFKQIAKRVIQEDTFSSFYGDVSTDTIRLAKAIVDDPSIAPAAAPNLYKQYAAMDRAVLQRPGFALGLALYSTRISSYESINSENGRGWYTGAGATYLYNQDLAQYSEDYWPTVDAYRIPGTTVASGTPIASGTGTSSWTGGVSLAGQYGASGMDLSYGAYNLSARKSWFMFDDEIVALGSGISSTAGIPIETVVDNRKLNGAGDNAWTANGAALSTGLGVAQTLTGVNWVHLAGNTADGSDIGYYFPGGATLQTKREARTGTWKQINNRPATPSTAVTRNYETMWIDHGTNPSGASYGYVLLPNKTSAQVGAYAADPAIEIVVNTSGVQSVKEKTLGLVGANFWTDTTQTADLITSNKKASVMTREIADERLEASVSDPTQANNGTIAIELARSAEGYSADPGITVTQLAPTIKFTVNVNGAKGKSFHASFQLGEDTSGPVDPGEPELPSVIVDNADSAGVTRTGTWKTASTQTDRYGANYLHDDNAGKGTKSVTFTPNLPIAGSYEVYLMWPAHFNREDAVQVDVGHASGTTRTAVDQRSGGGVWHSIGTYEFLAGSGGSVTIRNDALGSPDGYVVADAVKFVAVG",
    "output": "Plays a role in xanthan depolymerization pathway by cleaving the linkage between the terminal mannosyl and glucuronyl residues of the side chain of xanthan to liberate pyruvylated mannose. Is highly specific for pyruvylated side-chains of xanthan and is not effective with hyaluronate, chondroitin A, gellan, heparin or pectin."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEFVAKLFKFFKDLLGKFLGNN",
    "output": "Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEIIQDLSLEDVIGDRFGRYSKYIIQERALPDVRDGLKPVQRRILFAMYSSGNTYDKNFRKSAKTVGDVIGQYHPHGDSSVYDAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSQLSEELLRDINKETVSFIPNYDDTTLEPMVLPARFPNLLINGSTGISSGYATDIPPHNLAEVIQGTLKYIDQPDITINQLMKYIKGPDFPTGGIIQGIEGIKKAYETGKGKVVVRSRVDEEPLRSGRKQLIVTEIPYEVNKSSLVKKIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDANSESIKNYLYKNSDLQISYNFNMVAISEGRPKLMGLREIIESYLNHQIEVVTNRTRYDLEQAEKRMHIVEGLMKALSILDEVIALIRNSKNKKDAKDNLVAEYDFTEAQAEAIVMLQLYRLTNTDIEALKKEHEELEALIKELRNILDNHEALLAVIKDELNEIKKKFKVDRLSTIEAEISEIKIDKEVMVPSEEVILSLTQHGYIKRTSTRSFNASGVTEIGLKDGDRLLKHESVNTQDTVLVFTNKGRYLFIPVHKLADIRWKELGQHISQIVPIDEDEEVVNVYNEKDFKNEAFYIMATKNGMIKKSSASQFKTTRFNKPLINMKVKDKDELINVVRLESDQLITVLTHKGMSLTYSTNELSDTGLRAAGVKSINLKDEDYVVMTEDVNDSDSIIMVTQRGAMKRIDFNVLQEAKRAQRGITLLKELKKKPHRIVAGAVVKENHTKYIVFSQHHEEYGNIDDVHLSEQYTNGSFIIDTDDFGEVESMILE",
    "output": "Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTCSQTLGNNNTNKYQICEEIGRGRFGTVSRVYAPATGDFFACKTIDKASLSDDLDRACLDNEPKLMALLSYHPNIVQIHDLIDTDSTLSIFMELVHPSVSIYDRLVSSGTFFEPQTASFAKQILQALSHCHRYGVVHRDIKPENILVDLRNDTVKICDFGSGIWLGEGETTEGVVGTPYYVAPEVLMGYSYGEKVDLWSAGVVLYTMLAGTPPFYGETAEEIFEAVLRGNLRFPTKIFRGVSSMAKDFLRKLICKDASRRFSAEQALRHPWIQRAGETEERFI",
    "output": "Calcium-independent kinase involved in light-dependent phosphoenolpyruvate carboxylase phosphorylation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATKFPSFSQGLAQDPTTRRIWYGIATAHDFESHDGMTEEQLYQKLFSTHFGHLAIIGLWVAGNLFHIAWQGNFEQWVLDPLHTRPIAHAIWDPHFGQGLTDALTQAGATSPVNIAYSGLYHWWYTIGMRTNEQLFQGAIFINILVCWLLFAGWLHLQPKYRPSLAWFKNAESQLNHHLAVLFGFSSIAWTGHLIHVAIPESRGIHVGWENWLTVMPHPEGLTPFFSGNWGAYAQNPDSIDAVFGTSQGAGTAIFTFLGGLHPQSESLWLTDIAHHHLAIGVVFIIAGHMYRTNFGIGHSLKEIIEAHNTSHPKDPHRGYFGIKHNGLFETVNNSLHFQLGLALASLGVACSLVAQHMGALPSYAFIARDYTTQSALYTHHQYIAMFLMVGAFSHGAIFFVRDYDPELNKDNVLARILSTKEALISHLSWVTMLLGFHTLGIYVHNDVVVAFGTPEKQILIEPVFAQFAQAASGKMMYGFNALLANASSSASIAANSMPGNHYWMDMINRPDALTNFLPIGPADFLVHHAIALGLHTTALILIKGALDARGTKLIPDKKDLGFAFPCDGPGRGGTCDSSSWDATYLAMFWALNTIAWITFYWHWKHLAIWMGNTAQFNESGTYLMGWFRDYLWLNSSQLINGYNPFGVNALSPWAWMFLFGHLIWATGFMFLISWRGYWQELIETLVWAHQRTPIANLVGWRDKPVALSIVQARLVGLTHFTVGNFVTFGAFVIASTSGKFG",
    "output": "PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGRGKGGKGLGKGGAKR",
    "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLLTKRFSKLFKLTFIVLILCGLFVITNKYMDENTSVKEYKEYLDRYVQSYSNKYSSSSDAASADDSTPLRDNDEAGNEKLKSFYNNVFNFLMVDSPKGSTAKQYNEACLLKGDIGDRPDHYKDLYKLSAKELSKCLELSPDEVASLTKSHKDYVEHIATLVSPKGTYKGSGIATVGGGKFSLMAFLIIKTLRNMGTTLPVEVLIPPGDEGETEFCNKILPKYNSKCIYVSDILPRETIEKFVFKGYQFKSLALIASSFENLLLLDADNFPIKPLDNIFNEEPYVSTGLVMWPDFWRRTTHPLYYDIAGIAVDKKKRVRNSRDDITPPAVYTKDLKDLSDVPLSDLDGTIPDVSTESGQLMINKTKHLATALLSLFYNVNGPTWYYPIFSQKAAGEGDKETFIAAANFYGLSFYQVRTRTGVEGYHDEDGFHGVAMLQHDFVQDYGRYLNAMESIGNKYGGTKSADAIKFDKNYSLEKYTEEFFDNEDLNAKNHVDVMFIHSNFPKFDPYDLSKSNFLTTNGKPARSYTALKKVKNYDIELENFKVLNEYVCVNKNPFKYLDDLLGQDKTEWKRVCGYITDRLAFLESTHDKAIAGK",
    "output": "Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLMNKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTNVSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDRLSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVAVVTQEIIASAGGAGSKFGTGGMLSKIQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVTHD",
    "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MWGRKRPNSSGETRGILSGNRGVDYGSGRGQSGPFEGRWRKLPKMPEAVGTDPSTSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMTHPEGVASLLPPDFQSSLNRPELELSTHSPRKSSSFSEEKGESDDEKPRKGERRSSRVRQAKSKLPEYSQTAEEEEDQETPSRNLRVRADRNLKIEEEEEEEEEEEDDDDEEEEEVDEAQKSREAEAPTLKQFEDEEGEERTRAKPEKVVDEKPLNIRSQEKGELEKGGRVTRSQEEARRSHLARQQQEKETQIVSLPQEENEVKSSQSLEEKSQSPSPPPLPEDLEKAPVVLQPEQIVSEEETPPPLLTKEASSPPTHIQLQEEMEPVEGPAPPVLIQLSPPNTDAGAREPLASPHPAQLLRSLSPLSGTTDTKAESPAGRVSDESVLPLAQKSSLPECSTQKGVESEREKSAPLPLTVEEFAPAKGITEEPMKKQSLEQKEGRRASHALFPEHSGKQSADSSSSRSSSPSSSSSPSRSPSPDSVASRPQSSPGSKQRDGAQARVHANPHERPKMGSRSTSESRSRSRSRSRSASSSSRKSLSPGVSRDSNTSYTETKDPSCGQEAAAPSGPQLQVLEPKEKAPTFSASVRGRHLSHPEPEQQHVIQRLQPEQGSPKKCEAEEAEPPAATQPQTSETQISHLLESERTHHTVEEKEEVTMDTSENRPENEVPEPPLPVADQVSNDERPEGGAEEEEKKESSMPKSFKRKISVVSATKGVQAGNSDTEGGQPGRKRRWGASTAATQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEKEPEAELPAPPQVSVEVALPPPVEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKAEEQGAPRPLHPPPPPPVQPPPHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTESQIVQKEAEQAERAKEREKRRKEREEEEQKEREKEAERERNRQLEREKRREHSRERERDRERERDRGDRERERERDRDRGRERDRRDTKRHSRSRSRSTPVRDRGGRR",
    "output": "Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets; ACIN1 confers RNA-binding to the complex. The ASAP complex can inhibit RNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function. Induces apoptotic chromatin condensation after activation by CASP3. Regulates cyclin A1, but not cyclin A2, expression in leukemia cells (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDNTSKINKITKIEVQKRNKKRVNLYINDEYAMAFSTELAFKHNLKIGQEVDYKELKVIAEEDNYIKCKGDALKFIEKSYKTERQVYDKLLSKGYDNKTIERVIDFLTEYKFIDDWRFGELYIEERLKREGRNKIKYSLMQKGISESIIDEKLNCVDRDKEKDALNKIAEKKYKSILKNEEDKTKIYNKLGRFLMSKGYLWEDVKSVLNKLLYSDG",
    "output": "Modulates RecA activity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATTNSQSHYSYADNMNMYNMYHPHSLPPTYYDNSGSNAYYQNTSNYQGYYPQESYSESCYYYNNQEQVTTQTVPPVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPVPMYHHHQTTAAYPAYSHSHSHGYGLLNDYPQQQTHQQYDAYPQQYQHQCSYQQHPQDLYHLS",
    "output": "May play a role in determining neuronal identity, may be directly involved in specifying identity of individual neurons. Required during embryogenesis for the process of body segmentation. Homeotic protein, required in alternating segment primordia, it specifies the correct number of segments."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAPARQELQHESRCRPSRTVDAWRAAVATRGRHMETPGYRRRTRCGGWGLPRSVSSLAAVGLLCTALTTFICWGQLPPLPWASPAPQRLVGVLLWWEPFRGRGGYPKSPPDCSLRFNISGCRLLTDRAAYGEAQAVLFHHRDLVKELHDWPPPWGARERTDKALVLRVFDDQEGAVTLTGKALETVGSRPPGQRWVWMNFESPSHTPGLRGLAKDLFNWTLSYRTDSDVFVPYGFLYSRSDPTEQPSGLGPQLARKRGLVAWVVSNWNEHQARVRYYHQLSRHVSVDVFGRTGPGRPVPAIGLLHTVARYKFYLAFENSRHVDYITEKLWRNAFLAGAVPVVLGPDRANYERFVPRGAFIHVDDFPNAASLAAYLLFLDRNVAVYRRYFRWRRSFAVHITSFWDEQWCRTCQAVQTSGDQPKSIHNLADWFQR",
    "output": "Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins . Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity. Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins . Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis . In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEGTGLLTAVLVFLFAAVVAVPIAQRLGIGAVLGYLIAGIAIGPWGLGFIRDVDEILHFSELGVVFLMFIIGLELNPAKLWQLRRSIFGVGAGQVVITAAVLGALLYFTQFAWQAAVIGGVGLAMSSTAMALQLMREKGMNRNEGGQLGFSVLLFQDMAVIPALALIPILAGNEGGANDWVKIGLKIAAFAGMLIGGRYLLRPLFRYIVASGVREVFTAAALLVVLGSALFMDALGLSMALGTFIAGILLAESEFQHELEIAIEPFKGLLLGLFFISVGMALDLGVLFTHLLDVLLGVLALVFIKSAILYGLARVFGLRRSVRLQFAGVLSQGGEFAFVLFSAAFSQRVLNAEQLALLLVVVTLSMMTTPLLMQVIDRILVRRYNAQEESDEKPFVEDNDPQVIIVGFGRFGQVIGRLLMANKMRITVLERDVSAVSMMRKYGYKVYYGDATELELLRAAGAEKAKAIVITCNEPEDTMALVHLCQQHFPNLHILARARGRVEAHELLQNGVKDFTRETFSSALELGRKTLLELGMHPHQAYRAQQHFRRLDMRMLRELMPQHHGDVAQISRIKEARRELEDIFQREMLHESRQLDGWDEYE",
    "output": "Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEAQYSGVGSIPENSRSSHELGIQDQGSPQLRIVLLGKTGAGKSSTGNSILGRKAFLSGICAKSITKVCEKGVSIWDGKELVVVDTPGIFDTEVPDADTQKEITRCVALTSPGPHALLLVIPLGCYTVEEHKATRKLLSMFEKKARRFMILLLTRKDDLEDTDIHEYLETAPEVLQELIYEFRNRYCLFNNKASGAEQEEQKRQLLTLVQSMVRENGGKYFTNKMYESAEGVIQKQTWKKKEFYREELERERARIRREYEAEIQDLRDELERERRRARMEREFNENELIFAERQQNARREVENTSMIYLN",
    "output": "During thymocyte development, may play a role in the regulation of apoptosis (By similarity). GTPase which exhibits a higher affinity for GDP than for GTP (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPGIPQKALKWMLEKHAPLKIQPSLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECLKALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQSGVRFELLNVAQCLTHEPGLAPVQEKLVGGLWLPDDETGDYYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQTDLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYKVALTRFSDRIRVAGTAELAGFDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMTPDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVLTHGESPLSRLGLDLFRYPKAS",
    "output": "Oxidative deamination of D-amino acids."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTNIRKSHPLMKIINNSLIDLPAPSNISSWWNFGSLLGICLALQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWVLRYLHANGASMFFICLYLHVGRGLYYGSYMHTETWNVGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGKDLVEWIWGGFSVDKATLTRFFAFHFLLPFIISALVMVHLLFLHETGSNNPTGIPSDMDMIPFHPYYTIKDVLGLLLMIMILLTLVLFSPDMLGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILIIIPLLHTSKQRSMTFRPLSQCLFWLLAADLLALTWIGGQPVEHPYIIIGQFASILYFSIIIILMPLTSLVENHLXKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVEADHPGKLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDRTSKSRGFAFITFENPADAKNAAKDMNGKSLHGKAIKVEQAKKPSFQSGGRRRPPASSRNRSPSGSLRSARGSRGGTRGWLPSQEGHLDDGGYTPDLKMSYSRGLIPVKRGPSSRSGGPPPKKSAPSAVARSNSWMGSQGPMSQRRENYGVPPRRATISSWRNDRMSTRHDGYATNDGNHPSCQETRDYAPPSRGYAYRDNGHSNRDEHSSRGYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESYSRGYRNRRSSRETREYAPPSRGHGYRDYGHSRRHESYSRGYRNHPSSRETRDYAPPHRDYAYRDYGHSSWDEHSSRGYSYHDGYGEALGRDHSEHLSGSSYRDALQRYGTAHGAPPARGPRMSYGGSTCHAYSNTRDRYGRSWESYSSCGDFHYCDREHVCRKDQRNPPSLGRVLPDPREACGSSSYVASIVDGGESRSEKGDSSRY",
    "output": "RNA-binding protein which may be involved in spermatogenesis. Required for sperm development, possibly by participating in pre-mRNA splicing in the testis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSAPTHQQDLIALLEERGFVHQCTDREGLAAHLAAGPVTAYLGFDATADSLHVGHLQGLMLMRWLQKAGHRPLLLIGGATTRIGDPSFRDSSRPILGEAQIQANIDGIVRVFSRYVALDEGSLVNNAEWLDGVGYLEFLDQVGRHFSINRLLTFDAIRQRLDREHSLSFLEFGYTLLQAYDFVELSRRRGCTLQLGGADQWANIINGVELSRRQGGAQLFGLTMPLLATRDGRKMGKSAQGAVWLNAERLAPFDFWQFWRNCDDRDVARFLALFSELPMDEVRRLGALQGAELNEAKVVLANAATALAHGADAARAAADAARGVFADGARDAGLPLVRISRERLAQGLSLTELLVDNALQASRGAVRRLAAGGGLRLDGMPVADPDAPLTGEVDGRRLSLGKKQHLQLRLDD",
    "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTTDFLFPKIADCSYVSCYCEENVWKLCEQVKRTRPEELSKCYAVFVSNEGRTVPLWRQKAGRGDDQVVIWDYHVFFIHNPLLNRCLVFDLDTTLPFPTYFHKYVTETFRSDLALRPEHHRFFRVIPADTYLIEFSSDRRHMRRPDGSWIKPPPSYPPILSNSNMHCLGDFICMSAGKGPGAVYSLSEFVQNFYKSPHVMAQNNK",
    "output": "Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAAATAAASPVEGLTGGGGGGGGGVDGLFVELWRACAGPLVTVPAVGERVFYLPQGHIEQVEASTNQVAEQQGAPLYNLPWKIPCKVMNVELKAEPDTDEVYAQLTLLPEKQQDGNGSGNGNVSKDKVEEEEVVPPAATERPRVHSFCKTLTASDTSTHGGFSVLRRHADECLPPLDMSQHPPTQELVAKDLHGVEWRFRHIFRGQPRRHLLQSGWSVFVSAKRLVAGDAFIFLRGENGELRVGVRRAMRQQANIPSSVISSHSMHLGVLATAWHAVNTGTMFTVYYKPRTSPSEFVVPRDLYKESLKRNHSIGMRFKMTFEGEEAAEQRFTGTIVGVGDSDPSGWADSKWRSLKVRWDEAASVPRPDRVSPWQIEPANSPSPVNPLPAPRTKRARPNVLASSPDLSAVNKEVASKVMANSQQNGLPRAFHSQENMNLRSRFGDSNELNTSQKLTMWSSGSNQEKNNVSVQRELGSQSWMQMRRPDGSSEILSGFQPLKDTRNPLSSFPSQISGNRSNTWNTINVHYPDQNANHNMYPGTWSLMPPNTGFGVNQQNYLMTPDITLPQRSLNAKFGGNGAFTSLRAHGIDQRSSGWLGHIEPSSHIDDASSSLIKPQPLVIDHNVQKAKGSSCMLFGISLDSPAKPELLISPPSVAFDGKLQQDALEEDECSDPSKTVKPLDGAQHDSAREKHQSCPDGTKNIQSKQQNGSSRSCKKVHKQGIALGRSIDLTKFTCYDELIAELDQMFDFNGELNSSSKNWMVVYTDNEGDMMLVGDDPWNEFCNMVHKIFIYTREEVQKMNPGALNSRSEDSRSTSVERGLVGEGLQGGLSTPSLNSENC",
    "output": "Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNPNFLDFEQPIADLQAKIEGLRLVGNDNSLNISDEIARLQDKSNTLTESIFGNLTSWQIARLARHPRRPYTLDYLEHIFTEFEELHGDRHFSDDAAIVGGTARLDGKPVMVIGHQKGREVREKVRRNFGMPRPEGYRKACRLMEMAERFKMPILTFIDTPGAYPGIDAEERNQSEAIAWNLRVMARLKTPIIATVIGEGGSGGALAIGVCDQLNMLQYSTYSVISPEGCASILWKTADKAADAAEAMGITAERLKSLNIVDKVIQEPLGGAHRDPAKMSESIRADLVQQLDMLGKFDNDALLARRYERLMSYGL",
    "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK",
    "output": "Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer-membrane proteins including the iron transport operon (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARKTLTTALVKKFIPSRKSKSRKGENGIVLVVGGSYIYHGAPILSSIAALRSGTDLVYTSVPKINVASTRSVSPNLIVIPLVDQKLTRGAVNKLLGALPRKLDSATIGMGLAIQEKNALLHLVKSLLDRDVRLSLDASALIPEVLPLLANKNVVVTPHAGEFKRLFGQVPSNSKNERIKLVEEKAKEFGITVLLKGSTDIISNGSTTYLYEKKIPAMTVGGTGDVLSGLVAGLLSKNRKPLESAAAAAFINGLAGKVVQKKLGLHMTSMDLLPEISTVMKPFDKIM",
    "output": "Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKQRGVTVWLTGLSGAGKSTITEALQAKLIAEGYSIEVLDGDIVRTNLTKGLGFSKEDRDENIRRIGFVSNLLTRHGVIVLVSAISPYREIREEVRGKIGNFVEVFVNAPLSVCEDRDVKGLYKRARAGEIKSFTGIDDPYEPPFNPEVECRTDLETLEESVAKVWNKLTELGYIHQAVAV",
    "output": "Catalyzes the synthesis of activated sulfate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEEFQGYLELYRSWQDNFLYPLILQESIYALVHNQDLGLNGSILLSKKKGYDTKYSLLVVKRLVIRMYQQNFVILSLNDSNKNEFFVPNKNLYSQRISEGFAVLAEIPFSMRVMSSLKGKERKQYQNLRSIHSIFPFLEDKFSRLNHVLDILIPHPVHTKILVQTIRYCVKDISCLHLLQLLLYEYCNNGITLKGSVSNLSKNKNQRFLLFLYNSYVCECESIFVFLRNQSSHLRSTSYGAFLARVYFYLKLEHFLKVFTKHFRVILQFFKDPFMHYVRYQGKWILASRGTFLLMTKLKYYFVNFWQCNFYLWLQTRRIYINKSLNQPIDFIGFLLSVRLNPSVVRSQMLENSFLIYNGIKKFETLVPTMSLIGSLAKAKFCNVLGHPISKPAWADLSDSDIIRRFGRMCRNLSHYYSGSSKKGGLYRIKYILRLSCARTLARKHKSTVRAFMKRLGSEFFEEFFFKEEKVISLILSRDSSISRRLYRGPIWYFDIFCIHDLASHND",
    "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAISAWMPLLVALIVVWISAAEVDAQVPGPRTRYQPNWASLDQRPLPQWYDDAKVGIFLHYGVYSVPSFGSEWFWTNWKNLRNPEYVQFMQRNYKPDFTYQEFASQFTAELFNATKWALLFKDSGARYVVLTSKHHDGFTLWPSKNSYGWNSMDVGPKRDIVKELAAAIRKESDLRFGLYYSLFEWFNPLWTDDKLHLLMQQHFVERKVRPEQMELVQQYLPEIIWSDGDWEAPAKYWRSEEFIAWLYNDSPVRDTVVTNDRWGFGTACMHGDFYNCADRFNPGVLQAHKWENAFTLDRTSWGQRFDVSLSDFMTSKEVIKEIITTVSCNGNVLINVGPTKFGTILPIFEERLRDMGRWLKFNGEGIYGSVPWIYQNDTINGNVWYTRQKEASNGKITIYAFVLEYPYDTNELDIYPLGKDINIFRNVMLTGIDMGTGGDILNEQSTEVVMLGMEDTKIKWNADHNRLHIVFPPKNHIDKRGLDYAWTFKITIT",
    "output": "Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKIPLGILLSENQADKENILKHLEENSYIITVGDRTTEKMIDFDLIPSLQIVDGIEKREKREPPKLVNTTEITVDNPPAEITSQSIDVIKKAFSMESPVRILVTGEEDLLVLPVCIHAPENSVVMYGQPNEGLVIVKITSEIRNKVQSLLDLME",
    "output": "Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKRHLTRRQSWRIEKIQEERAARAARRESRAVEELEGGDLGPEQTGQVIAHFGVQVEVESADGQVSRCHLRANLPALVTGDQVVWRAGNQGIGVIVAQLPRRSELCRPDMRGLLKPVAANVDRIVIVFAPRPEPHANLIDRYLIAAEHAGIQPLLLLNKADLVDESNAEGIDALLNVYRTLGYPLIEVSAFNGLAMDELRGALDGHVSVFVGQSGVGKSSLVNALLPGVDTRVGDLSTVTGKGTHTTTTARLFHFPGGGDLIDSPGIREFGLGHVSRDDVEAGFIEFRDLLGHCRFRDCKHDREPGCALLQALEDGRIMPQRMASYRHILASMPETDY",
    "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNKIPIKDLLNPQITDEFKSSILDINKKLFSICCNLPKLPESVTTEEEVELRDILGFLSRANKNRKISDEEKKLLQTTSQLTTTITVLLKEMRSIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHRFTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLSGEPLAKKKE",
    "output": "Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Silenced copy of ALPHA2 at HML."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MISEENFQQHTPMMQQYLKLKAENPDILLFYRMGDFYELFYDDAKKAAALLDISLTKRGQSAGQPIPMAGMPYHAVEGYLAKLVQLGESVAICEQIGDPTTSKGPVERQIVRIVTPGTVSDEALLPERQDNLIAAVYQEKEKFGLATLDMTSGRFQLCEPADKETLRAELQRIAPVELLYCEEFNEMAAIEHCKGLRRRPIWEFELSTAITLLNRQFGTKDLRAFGVEKSPLGLSAAGCLLQYAKETQRTALPHIQSISLIQNQDCIQLDAATRRNLELTQNLAGGTENTLASVLDKCVTPMGSRLLKRWIHQPVRDVEKLKQRQQSIAEILNFDLVDELQPYLQLVGDMERILARVALRSARPRDLTRLRTALEQIPALRAIVQQKTPPFLTALFSQIADFSEQCDLLQRALIETPPLLIRDGGVIAEGYNAELDEWRMLSDGATQYLENLEKRERESTGIDTLKIGFNAVHGYYIQISQGQAHKAPIHYVRRQTLKNAERYIIPELKEYEDKVLKSKGAALALEKQLYDELFDLLLPHLGSLQLASLALSELDVLVNLAERADTLNYVMPTFCDEVSVKIKNGRHPVVEQVLKDPFIANPVELNHNRHLLVITGPNMGGKSTYMRQTALITLLAYIGSFVPADSARIGPIDRIFTRIGASDDLASGRSTFMVEMTEMANILHQATAQSLVLIDEIGRGTSTYDGLSLAWACAEWLSKKIRSLTLFATHYFELTALPEQLEGIANIHLDALEHNNTIAFMHAVQNGAASKSYGLAVAALAGVPQSVIKLAKQKLTQLEKNSSYSAEQQIQALREANHNQGELFFEQETDALREAIEKLDPDDLSPKQALAYLYQLKKMVG",
    "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTENKCPVTGKMSKATAGSGTTNKDWWPNQLNLNILHQNSQLSNPMSKDFNYAEEFKKLDFQALKVDLYMLMTDSQIWWPADYGNYGPFFIRMAWHSAGTYRVGDGRGGGSFGLQRFAPLNSWPDNINLDKARRLLWPIKKKYGNKISWADLMILTGNCALESMGLKTLGFGGGRVDVWEPQEDIYWGSEKEWLGDEREKDDEELENPLAAVQMGLIYVNPEGPNGNPDPLGSAHDVRETFARMAMNDEETVALVAGGHTFGKCHGAASPSYVGPAPEAAPIEEQGLGWKNTYGSGNGDDTIGSGLEGAWKANPTKWTMGYLKTLFKYDWELVKSPAGAYQWLAKNVDEEDMVIDAEDSTKKHRPMMTTADLGLRYDPIYEPIARNYLKNPEKFAHDFAAAWFKLTHRDMGPISRYLGPEVPKESFIWQDPIPLVKHKLITKKDITHIKKKILDSGLSISDLVATAWASASTFRGSDKRGGANGARIRLEPQKNWEVNEPKKLNNVLNTLKQIKENFNSYHSKDKKVSLADIIILGGCVGIEQAAKRAGYNINVPFIPGRTDATQKQTDVKSFAVLEPKGDGFRNYLKTKYVVKPEDMLIDRAQLLTLTAPEMTVLIGGMRVLNCNYNKSKDGVFTNRPECLTNDFFVNLLDMNTVWKPKSEGKDRFEGFDRETGELKWTATRVDLIFGSNSQLRAIAEVYACDDNKEKFIQDFIFAWNKIMNADRFEIK",
    "output": "Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKKSMIERDKKRARMVAKYAAKRAALKEAFNNAADPLEKLEIHRKIQNLPRNSSPTRMRNRCQITGRPRSYYRDFGLCRNVLRDWAHQGLLPGVVKSSW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSGLLQLDEESLYDHIFERYTLLTSNNDSLKQDLGIVDRTVSKITIDIDQFDFNNKKSNNDFYSIEINQPITSLNSSSVNNNSTTGYVVWSTTPFFTRWLIFHSNASIFRNGGSIELIDQDDELKLPPMFSNSVGLLELGSGIAGILPVTLGNFVGSFIATDQIGILSTLKTNILENLSQLNRKIVTSRSLNLNLDVDESTLLKRSLLSLECLPLDWELFDIKDTTKLDPALLSLFKEKETIYVLAMDVIYNEYLIESFLSTIQNLKSLAFKFNVNLNCLIGIQLRSEEVTTLFLEKAIIDYEMKVYYIQDNILESSRFSIYMI",
    "output": "S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates 60S ribosomal protein L1."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSEAAHSGAAPADLVELGRIASAYGVKGWVKVQPHSAQAEVLRTVSHWWLTRPAPQAARDVVASVPRAYQVLQARVHGGAVVAQLAGIDDRDQAEALRGCFVQAARSAFPAPADDEYYWVDLIGCALYSDADGEPRLLGVVDEVFDNGAHAVLKVLRQQIQPGQPGPVPLLDPKGRPLEELVPFVRAHIRHVDLAARRIDSDWPLDY",
    "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFAKNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHGYYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVLKPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL",
    "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTSALENYINRTVAVITSDGRMIVGTLKGFDQTINLILDESHERVFSSSQGVEQVVLGLYIVRGDNVAVIGEIDEETDSALDLGNIRAEPLNSVAH",
    "output": "Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "REKIGVMFGCFSYGTRVQLADGSTEKIGKIVNQKMDVEVMSYDPVTDQIVPRKVVNWFNNGPAEQFLQFTVEKSGGNGRSQFAATPNHLIRTPAGWTEAGDLIAGDRVLAAERHLLSDQQFQVILGSLMGGGNLSPNLHDRNGVRFRMGHGARQADYLEWKTALLGNIGHSVRENDQGARFVDFTPLPELGELRRAVYLGDGKKFLSEDYLKALTPLALAVWYMDDGSFTVRSKGVQQRTQGGSGRIEICVEAMAEGTRERLRDYLRDTHGLDVRLRSAGSGKSMLTFSTEATAKFQELVAPHMAPSMEHKLLPRFRGLGTVEPRFVEPAQRLVPARVLDVQVKPRTRSMNRFDIEVEGNHNYFVDGVMVHNSPETTTGGKALKFYASVRMDVRRIETLKDGSDAVGNRTRVKVVKNKVSPP",
    "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFITDPISDMIVRIKNANQRKFKTVLIPYSNKKAKILEILLNEGYISSFVTKGEGKDKTLEVALKYKGNQSAIIDFKRISKPGLRVYAAANNLSSVLSGYGTVIISTSKGVMTEKQARKENVGGEVLAYIW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKLPIYLDYAATTPVDPRVAEKMFQYMTMDGIFGNPASRSHRYGWQAEEAVDIARNQVADLINADHREIVFTSGATESNNLAIKGVAHFYNKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLEPASNGIIPMERLEAAMRDDTILVSIMHVNNEIGVIHDIDAIGELCRSKGIIFHMDAAQSAGKLPIDVQATKVDLISISGHKMYGPKGIGALYVRRKPRIRLEAQMHGGGHERGMRSGTLPTHQIVGLGEAAAIAKAEMATDNERIGRLRDKLWNGIKHIEETYINGDLTQRFCGSLNVSFNYVEGESLMMALKDLAVSSGSACTSASLEPSYVLRALGLNDEMAHSSIRFSIGRFTTEEEIDHAIETITQSIDKLREMSPLWEMFKDGIDLNQVQWAHH",
    "output": "Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARMIQCAKLGKEAEGLDFPPLPGELGKRIYESVSKEAWQGWLKQQTMLINENRLNMADPRARQYLMKQTEKYFFGDGADQASGYVPPTEG",
    "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEIITSLQTELSNRHANMVSEAVLAFSEHHDSALHSYFLNARVKDVILESLRTTEEKLRALDKLQLDASKNLSNLLVEYNSINAELESVNSKISSISSQEYALEEFQALSQNFEKNLVQHRRNSQNKLKCAMEKLKMIETSTHKAILDNF",
    "output": "During meiotic DNA recombination, binds to and may help activate DNA double-strand break (DSB) hotspot sites."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRSPGIVLLLLLLLLLPPGAAPCPADLCPAPPRVNVSLDAAPAARWLPVLRLFDPGLLRAAVARIVGDRVPKWRDVIGKLVAEMESFLPQPYTKEIRGISDFLNLSLADGFIVNLAYEASAFCTSVVAQDSRGHIYHGRNLDYPFGDLLRKMTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPYKFTVSGDERDKGWWWENMIAALFQGHSPVSWLIRTTLSESEDFEASVYKLAKTPLIADVYYIVGGTAPGEGVVVTRNRGGPADIWPLDPLNGAWFRVETNYDHWKPVPKSDDRRTPAIKALNATGQANLSLEALFQVLSVVPVCNKITVYTTVMSAATPDKYMTRIRNLS",
    "output": "Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N-myristoylethanolamine > N-stearoylethanolamine > N-oleoylethanolamine > N-linoleoylethanolamine > N-arachidonoylethanolamine."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMTNLFSVFDPSAIFNLSLNWLSTFLGLLMIPSIYWLMPSRYNIFWNSILLTLHKEFKTLLGPSGHNGSTFIFISLFSLILFNNFMGLFPYIFTSTSHLTLTLSLALPLWLCFMLYGWINHTQHMFAHLVPQGTPAILMPFMVCIETISNIIRPGTLAVRLTANMIAGHLLLTLLGNTGPSMSYLLVTFLLVAQIALLVLESAVTMIQSYVFAVLSTLYSSEVN",
    "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFKVNEYFDGTVKSIGFAMAEGPATIGVMAPGEYEFGTSQLEVMHVVAGALTVKLPGSDSWSTFEAGSNFTVPANSKFQLKVAVDTAYLCEYR",
    "output": "Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNNDDISKFNALFEDVEQFLNI",
    "output": "Involved in the regulation of virulence genes. Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb. Binds directly to the agr promoter region."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVQISEVKGNSRDNRTAAHTHIKGLGLRPDGTAEVSGDGWVGQAAAREACGVVVDLIKAKKMAGRAVLLAGGPGTGKTALALAVSQELGTKVPFCPIVGSEIYSAEVKKTEALMENFRRAIGLRVRETKEVYEGEVTELTPQEAENPLGGYGRTISHLIIGLKSAKGTKKLRLDPSIYEAIQKERVTVGDVIYIEANTGACKRVGRSDAYATEFDLEAEEYVPVPKGEVHKKKEIVQDVTLHDLDIANARPQGGQDVMSMMGQLMKPKKTEITDKLRQEINKVVNRYIDQGVAELVPGVLFIDEVHMLDIECFTYLNRALESSISPIVILASNRGHTVIRGTDDISAAHGIPPDLLARLLIIPTHPYSPDEIKTIIRLRAKTEGLNITDPALDKVAEHGSKVSLRYALQLLTPASILARVNGRPGGIEEADVTECEDLFLDSKRSAAIVNQDSEKFLY",
    "output": "DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSEVINVNCPTCGKAVVWGEISPFRPFCCKRCQLIDLGEWAAEEKRIPSEGGLSDSDDWSEELK",
    "output": "Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKKKVVTQIKLQCPAGKATPAPPIGPALGPHGVSAPQFVQQFNDRTKSMEPGLVIPVVITVYADKSFTFILKTPPASVLIKKACKIEKGSATSVTAKVGKLSKAALEEIAKTKMPDINANDIEAAKKIIAGTARSMGVEVER",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MHALPRYAVFGNPAAHSKSPQIHQQFALQEGVDIEYGRICADIGGFAQAVSTFFETGGCGANVTVPFKQEAFHLADEHSDRALAAGAVNTLVWLEDGRIRGDNTDGIGLANDITQVKNIAIEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELARLFGIEAVPMADVNGGFDIIINGTSGGLSGQLPAVSPKIFRDCRLAYDMVYREAAKPFLDFARQSGAKKTADGLGMLVGQAAASYALWRGFKPDIRPVIEHMKAL",
    "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKTLVLLSALVLLAFQVQADPIQNTDEETKTEEQPGEEDQAVSISFGGQEGSALHEKSLRGLLCYCRKGHCKRGERVRGTCGIRFLYCCPRR",
    "output": "Host-defense peptide that has antimicrobial activity . Exhibits activity against Gram-negative E.coli (in vitro) . Probably contributes to the antimicrobial barrier function of the small bowel mucosa ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARAFLFVLDSFGVGGAPDAAAYGDEGADTLGHIAEFCAAGAGDRAGLRDGPLSLPNLSELGLMQIARSASGRFPAGMPIPEKVYGIYGAATEISRGKDTPSGHWEIAGTPVSFDWGYFPTEGDAFPEELIEALCRDAGVSGILGNCHASGTEIIARLGEEHIRTGKPICYTSSDSVFQVAAHEVHFGLDRLLAFCQVARGLLDRYNIGRVIARPFIGHSSSTFQRTGNRRDFSVLPPEPTLLDRLIEHGRHVHAVGKIGDIFAHQGISRLIKANGNEALMDATLATIDEAEDGDLVFTNFVDFDMVYGHRRDVPGYAAALEAFDARLAEVHKKLKPGDLVVLTADHGCDPTWRGTDHTRERVPVIAYGPGIRSRSIGVRRSYADIGESIARHLGIPAGPHGRSFL",
    "output": "Phosphotransfer between the C1 and C5 carbon atoms of pentose."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKVLGRSFFWVLFPVLPWAVQAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDDLGLSMLIDSQNNQYILTKPRDSTIPRADHHFIKDIVTIGMLSLPCGWLCTAIGLPTMFGYIICGVLLGPSGLNSIKSIVQVETLGEFGVFFTLFLVGLEFSPEKLRKVWKISLQGPCYMTLLMIAFGLLWGHLLRIKPTQSVFISTCLSLSSTPLVSRFLMGSARGDKEGDIDYSTVLLGMLVTQDVQLGLFMAVMPTLIQAGASASSSIVVEVLRILVLIGQILFSLAAVFLLCLVIKKYLIGPYYRKLHMESKGNKEILILGISAFIFLMLTVTELLDVSMELGCFLAGALVSSQGPVVTEEIATSIEPIRDFLAIVFFASIGLHVFPTFVAYELTVLVFLTLSVVVMKFLLAALVLSLILPRSSQYIKWIVSAGLAQVSEFSFVLGSRARRAGVISREVYLLILSVTTLSLLLAPVLWRAAITRCVPRPERRSSL",
    "output": "Probable Na(+)/H(+) antiporter."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMSTSRAVKSPACAARRRQWSADAPNRTATFLACRHGRRLGGGGGAPCSVRAEGSNTIGCLEAEAWGGAPALPGLRVAAPSPGDAFVVPSEQRVHEVVLRQAALAAAAPRTARIEPVPLDGGLKAAFHRCGEVCREYAKTFYLATQLMTPERRMAIWAIYVWCRRTDELVDGPNASHISALALDRWESRLEDIFAGRPYDMLDAALSDTVARFPVDIQPFRDMIEGMRMDLKKSRYRSFDELYLYCYYVAGTVGLMSVPVMGISPASRAATETVYKGALALGLANQLTNILRDVGEDARRGRIYLPQDELEMAGLSDADVLDGRVTDEWRGFMRGQIARARAFFRQAEEGATELNQESRWPVWSSLLLYRQILDEIEANDYDNFTRRAYVPKTKKLMALPKAYLRSLVVPSSSSQAESRRRYSTLT",
    "output": "Catalyzes the conversion of geranylgeranyl diphosphate to phytoene. Mediates the first committed step in carotenoid biosynthesis. May play a role in regulating carotenoid flux in response to abiotic stress in roots. May control flux to carotenoid precursors that are required for abiotic stress-induced abscisic acid (ABA) formation in roots."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDDISPSELKTILHSKRANLYYLQHCRVLVNGGRVEYVTDEGRHSHYWNIPIANTTSLLLGTGTSITQAAMRELARAGVLVGFCGGGGTPLFSANEVDVEVSWLTPQSEYRPTEYLQRWVGFWFDEEKRLVAARHFQRARLERIRHSWLEDRVLRDAGFAVDATALAVAVEDSARALEQAPNHEHLLTEEARLSKRLFKLAAQATRYGEFVRAKRGSGGDPANRFLDHGNYLAYGLAATATWVLGIPHGLAVLHGKTRRGGLVFDVADLIKDSLILPQAFLSAMRGDEEQDFRQACLDNLSRAQALDFMIDTLKDVAQRSTVSA",
    "output": "CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Involved in the integration of spacer DNA into the CRISPR cassette (By similarity). Acts as a ss- and dsDNA-specific endonuclease ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSNLNLATLDISEHANLPTSSEVLFKAKADKKLSFESIAAAIGRNEVATAAIFYGQAKASEEDIAKLAQVLEIDHAHLESLLSGFPDRGKSVSFPPKDPLIYRLYEIVQNYGYAYKAVMNEKFGDGIMSAISFSTTVEKETDKDGNNWAVVTWRGKWYV",
    "output": "Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEQTQTAEGTDLLIGDEKTNDLPFVQLFLEEIGCTQYLDSFIQCNLVTEEEIKYLDKDILIALGVNKIGDRLKILRKSKSFQRDKRIEQVNRLKNLMEKVSSLSTATLSMNSELIPEKHCVIFILNDGSAKKVNVNGCFNADSIKKRLIRRLPHELLATNSNGEVTKMVQDYDVFVLDYTKNVLHLLYDVELVTICHANDRVEKNRLIFVSKDQTPSDKAISTSKKLYLRTLSALSQVGPSSSNLLAQNKGISHNNAEGKLRIDNTEKDRIRQIFNQRPPSEFISTNLAGYFPHTDMKRLQKTMRESFRHSARLSIAQRRPLSAESNNIGDILLKHSNAVDMALLQGLDQTRLSSKLDTTKIPKLAHKRPEDNDAISNQLELLSVESGEEEDHDFFGEDSDIVSLPTKIATPKNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVSTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKKIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQSATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPGALELLQHPWLDAHII",
    "output": "Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast. It is thought that it phosphorylates the STE7 protein kinase which itself, phosphorylates the FUS3 and or KSS1 kinases (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNQSYFPHHQSDLSLQRVEAALDALRAGQGVLVTDDEQRENEGDLIFAAQSLTREQVAMLIRECSGIVCLCLTDEAVRRLDLPLMVSDNSSRYQTAFTVSIEAAEGVTTGVSAADRLTTIRAAIADDAGPLCLSRPGHVFPLRARPGGVLERRGHTEATVDLMRLAGLKPCGVLCELTNPDGSMARMPEIVAFSRKHGFPLITVEELVQYRIVREQPAALLQAEAESAGALCSA",
    "output": "Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHTQVHTARLVHTADLDSETRQDIRQMVTGAFAGDFTETDWEHTLGGMHALIWHHGAIIAHAAVIQRRLIYRGNALRCGYVEGVAVRADWRGQRLVSALLDAVEQVMRGAYQLGALSSSARARRLYASRGWLPWHGPTSVLAPTGPVRTPDDDGTVFVLPIDISLDTSAELMCDWRAGDVW",
    "output": "Catalyzes the coenzyme A-dependent acetylation of the 2' hydroxyl or amino group of a broad spectrum of aminoglycosides. It confers resistance to aminoglycosides (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSFPVEVLAGIAIELQRGIGHQDRFQRLITTLRQVLACDASALLRYESRQFIPLAIDGLAQDVLGRRFTLEGHPRLEAIARAGDVVRFPADSDLPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDAMTPEQFEVFSDEELRLVAALAAGALSNALLIEQLESQNMLPGSSGVFEPIKETHMIGLSPAMTQLKKEIEIVAGSDLNVLIGGETGTGKELVAKAIHQGSPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLFVPPLRERGDDVVLLAGYFCEQCRLRLGLSRVVLSPGARRHLLNYGWPGNVRELEHAIHRAVVLARATRAGDEVVLEEQHFALSEDVLPAPSAESFLALPACRNLRESTENFQREMIRQALAQNNHNWAASARALETDVANLHRLAKRLGLKD",
    "output": "Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL",
    "output": "Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGKVELHGKIMEVDYSVSKKLRSRRIQIRNIPPHLQWEVLDGLLAEYGTVENVEQVNTDTETAVVNVTYMTREEAKLAIEKLSGHQFEDYSFKISYIPDEEVSSPSPPHRAREQGHGPGSSSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEVPLKILAHNGFVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVRGTIEACANAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLPPPAGPRGVPPSPPYHPFATHSGYFSSLYPHHHFGPFPHHHSYPEQETVSLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQRYPQGVAPQRSK",
    "output": "RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta-actin/ACTB and MYC transcripts (By similarity). Increases MYC mRNA stability by binding to the coding region instability determinant (CRD) and binding is enhanced by m6A-modification of the CRD (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVTRRRLHHPEVEQVSKRQKVDKAESKNKKHADVAAERGEQSTEDHEDESQDKKDKKVVGDNRDEDEEVSPNGQEAAEDNDDRKDKDAKEKDTETNDEGTEKSHTDVNDDDDDVDESKEEDAAAAVDITKEKKDEQESDNKTEEKKVQENEEEEEEDENKNDEDVEELGSTEPVDDEKKGLVKFEFDGVEYKFKERASVIEENEGKIEFRVVSNDNTRENMMVLTGLKNIFQKQLPKMPKEYIARLVYDRSHLSMAVIRKPLTVVGGITYKPFNKRQFAEIVFCAISSTEQVRGYGAHLMNHLKDYVRNTSDIRYFLTYADNYAIGYFKKQGFTKDITLDKKVWMGYIKDYEGGTLMQCSMLPRIRYLDAAKILLLQEAALRRKIRTISKSHVVHPGLECFNDIENIKPIDPMSIPGLKEAGWTPEMDELAQRPKRGPHYAAIQNILVELQNHAAAWPFLRPVNKEEVPDYYEFIKEPMDLSTMELKLENNKYEKMEEFIYDARLVCNNCRLYNGENTSYYKYANRLEKFFNNKVKEIPEYSHLID",
    "output": "Histone acetyltransferase that acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H3 to form H3K14ac, with a lower preference histone H4 to form H4K8ac and H4K16ac, and contributes to H2A.Z acetylation. Acetylation of histones gives a specific tag for epigenetic transcription activation. In addition to histone acetyltransferase, can use different acyl-CoA substrates, such as (2E)-butenoyl-CoA (crotonyl-CoA) and is able to mediate histone crotonylation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKAKLLILFCAFTATDADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPLQLGNCSIAGWILGNPECESLFSQKSWSYIAETPNSENGTCYPGYFADYEELREQLSSVSSFERFEIFPKESSWPNHTVTKGVTASCSHKGRSSFYRNLLWLTEKNGLYPNLSKSYVNNKEKEVLVLWGVHHPSNIGDQRAIYHTENAYVSVVSSHYNRRFIPEIAKRPKVRGQEGRINYYWTLLEPRDTIIFEANGNLIAPWYAFALSRGFGSGIITSNASMDECDAKCQTPQGAINSSLPFQNVHPVTIGECPKYVRSTKLRMATGLRNIPSIQSR",
    "output": "Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENINNDEDPEGSVDPEGQGS",
    "output": "Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTYSRNIFIPLTRACRNRCGYCTFRSDTPEPPLLEPEDVMGEVRRALSLGCTEALFTFGEDAHEFPGVRDKLESLGFGDMTDYTYHLCELTLDAGLLPHTNMGVIGYRELRMLKEVNASMGLMLESASPRLMETEAHRESPGKNPRLRIKMIEDAGRLRIPFTTGLLIGIGETIEERAESLLELRRIQDRYGHIQEIIIQNFRSKPGIPMENQREPSLLEMVKMVAAAKIMFPDVSIQVPPNLNRETGEIFLLAGADDWGGVSPISRDYVNPEAPWPEIDELKRITESAGFALEERLPVYRKFISREFLSPRVMERIEELYPRFIETL",
    "output": "Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MMKMRWLGAAIMLTLYASSSWAFSIDDVAKQAQSLAGKGYEAPKSNLPSVFRDMKYADYQQIQFNSDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATTVKRIKYSPDYFNFGNVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFREFWIERPKPTDKRLTVYALLDSPRATGAYRFVIIPGRDTVVDVQSKVYLRDKVGKLGVAPLTSMFLFGPNQPSPTTNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSYAMENPQGFGLLQRGREFSRFEDLDDRYDLRPSAWITPKGDWGKGKVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTLTFSRDEDKLHAPDNAWVLQTRRSTGDVKQSNLIRQPDGTIAFVVDFVGADMKKLPPDTPVAAQTSIGDNGEIVDSNVRYNPVTKGWRLMLRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE",
    "output": "Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAIFTPELWLICFAVTVYIFDYIYTKYLMYKLGAKPITHVIDDGFFGFRLPFLITLANNQGRLIEFSVKRFLSSPHQTFMNRAFGIPIILTRDPVNIKAMLAVQFDEFSLGLRYNQFEPLLGNGIFTSDGEPWKHSRIMLRPQFIKSQVSHVNRLEPHFNLLQKNITAQTDNYFDIQTLFFRFTLDTATEFLFGQSVHSLNDGENSLQFLEAFTKSQAILATRANLHELYFLADGIKFRQYNKMVQDFSQRCVDKVLNMSNSEIDKLDRYFFLYEMVKITRNPQVLRDQCLNILLAGRDTTASLLSFAFFELALNEPIWIKLRTEVLHVFQTSLELITFDLLKTKCPYLQAILHETLRLYPSVPRNARFSKKNTTLPHGGGVDGMSPILIKKGQPVAYFICATHVDEKFYTKDALIFRPERWCEEPLIKKNLAWSYLPFNGGPRICLGQQFALTEASYVLTRLAQCYTKISLQPNSFEYPPKKQVHLTMSLLDGVHVKISNLSIS",
    "output": "Together with an NADPH cytochrome P450 the enzyme system catalyzes the terminal hydroxylation as the first step in the assimilation of alkanes and fatty acids."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGFGFIISDWNMPNMDGLELLKTIRADSAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM",
    "output": "Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Shows autophosphatase activity which is enhanced by CheZ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR",
    "output": "This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGKLMVPKILVTNDDGVYSTGLKAAFDSVSDLGEVTISAPAVQQSGVGRSISIFEPLRITKTDVGGIPAYAVGGTPTDSVILGVFTILKAMPDLVLSGFNIGENISTDTITTSGTIGGALEAASYGVPAIAASMQVLDEGQKFDDPRDYQRERFEAGIKVVNRIARNVLKRGMPENVDLLNINIPFHAEEDTPIEITRLARKIFKTDVEERRDPRGRPYYWIAGDLIREEEEGTDVHAIMQKGHVSITPISLDSTARIDFSEIERYL",
    "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLGFFAVYGNPITHSKSPFLHNYAFTKLGLSGYYSRILLDKGANLRQNFLSNGLSGANITLPFKEEAFNQCDEVRGVAQNIGACNTWVLEDKNHLVGYNTDAQGFYECIKEYKIKNALIIGAGGSAKAVAMILQSHNIPTTLINRSVQNLSFFVHKGFECYVNSEFKPTCSYDILINTTSAGLNDNLLPCDESQLKELCSCGKYAFDLIYGKCTPFLALAQSFHLSCSDGKEMLINQAALSFELFCKQKYNKGNLEIQRIASFMNEIL",
    "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMGLAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNPKLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAPRLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAVYSWNSLRRRRIPQISN",
    "output": "Confers resistance to fosfomycin and deoxycholate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKNNIVIITGITASGKSELCDNLREKYGNISIINCDSKQVYKEIPIITAQPLKQEEFYKLYGYVSAKENYSVGLWLEDLEKEVNHALENAQIPIITGGSGLYISSFIKGLSSMPQISQEVRKNVSELRKNLSKEEFYKLVLSKDSKVQDKICINDSHRLSRALEVITETGKTIFVWQENRQPPLFDNFKIYTILPKREDVYQKINSRFIKMIENGAIDEVKKLLSMNLAPNLPAMKAHGVPEIVKYLKGEITLDEAIQIAQTNTRHYAKRQYTWFKNQFPSSEVIDCANELTALEIF",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPIYDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQRVHLADGLGADNKLSEEAMERGLSCLSLFAERLQGFSPSSVCIVGTHTLRQAQNAADFLKRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPRLVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQYRIQGWNVAMGASGTIKAAHEVLLALGEKDGFITPERLDKLKSEVLKHRSFNALSLPGLSEERKAVFVPGLAILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTAKSLANQYNIDREQARRVLETTMQMYEQWQAQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQHSDLPGFNQEQQMMMATLVRYHRKAIKLDDMPRFTLFKKKQYLPLIQLLRLGVLLNNQRQATTTPPTLRLTTDDSHWTLCFPHDWFSQNALVLLDLEKEQQYWEAVTGWRLNIEEESSPEIAA",
    "output": "Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKVVKFPWLAHREESRKYEIYTVDVSHDGKRLATGGLDGKIRIWSIDSILRCMELESLTPEIPLPQDLQMPLCSMSRHTGSITCVKFSPDGKYLASGSDDRILLIWALDEEQSSQPAFGSEHEREHWTVRKRLVAHDNDIQDICWAPDSSILVTVGLDRSVIVWNGSTFEKLKRFDVHQSLVKGVVFDPANKYFATTSDDRTMKIFRYHKTGDISFTIEHIITEPFKESPLTTYFRRPSWSPDGQHIAVPNATNGPVSSVAIVNRGTWDTNVSLIGHDAPTEVARFNPRLFERNAGVKQKKDDDPENALVGQNDDKVHHFDKNIDSVVATAGQDKSLAVWSTSRPRPILVAFDIANKSITDMSWNPDGSLLFVASLDSSITLFKFENNELGKPIPLEKNMEQLYRYGVDKDSLDFPESINQLLLEDQTKSFKHTKISTSKLGENHPTLATNSASNQKDNNDASVSRSEHINILIPKRKKDAILNKAVTLKSGKKRVAPTLISTSSSSPFSNGIKKPTLDSKRIENNVKSSTKTINSKNTLLNVPEGVEKKISISSFPLPRLGIHSLIMGTKERSAWKISNSELENDDADNAGGKGSDGTSNSIDDIAVLSEEENDFHRMTLNAKLTQEKIWSEEPTTRCLLQSDVIPDTDVVVLEGGSLDDIAVLEIRNGVERSIQFDSEALLDNPTRILGYQGGKRTIETFIPEVIICAIGSKDCKCWCLASANGSIYILSYNGQQRIPKICLGHKVIKMVTSSKYLLVLTERGLFFAWDLLDLKLVLRNVPILPILNGQPIHGNKVRINKVIKCFRLDGSSCDLLLEVGDPKNVYKWTKDLGCWSLYK",
    "output": "Component of the HIR complex, which cooperates with ASF1 to promote replication-independent chromatin assembly. The HIR complex is also required for the periodic repression of three of the four histone gene loci during cell cycle as well as for autogenous regulation of the HTA1-HTB1 locus by H2A and H2B. DNA-binding by the HIR complex may repress transcription by inhibiting nucleosome remodeling by the SWI/SNF complex. The HIR complex may also be required for transcriptional silencing of centromeric, telomeric and mating-type loci in the absence of CAF-1."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQMMSLEKEAAMETKTAEQRSLDYRNAMARLGAAVNIVTTDGAAGRAGFAATAVCSVSDNPPTLLVCLNRNASAYKVVKANGVICINTLAAHHEVLSTLFGGKTPAEERFAAGSWGVLETGAPVLEDALVSFDCRIREAHDGGTHDILICTVVDMKINAGDEALMYFNRRYRVL",
    "output": "Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ",
    "output": "Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKTVKVAVTGAAGQIGYSLLFRIASGQMFGADTAVEIQMLELEAAIPAAKGVIMELEDCAFPLLQKVTVSSDLDTAFKEINWALLVGSVPRKAGMERGDLLKINGGIFVNQGKAIEKNAASDVRILVVGNPCNTNCLIAMNNAKGISQDRWFAMTKLDENRAKSQLASKAGVPVKEVTHLGIWGNHSATQYPDFYNTKISGKPVTDVISDHEWLKGDFIKNVQQRGAEIIKARGASSAASAANGVVDTVRGIITPTAPGDCFSAAVVSDGSYGAEKGLIFGFPLKSDGKKVEIIQGISLNDFAKEKFKITHEELVSERNEVKEML",
    "output": "Catalyzes the reversible oxidation of malate to oxaloacetate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPVAPHELRDTIKSRDLGLFQCIDLLKQHNDNIGVHHQLVQKLYSYSYDELEFFIPQFIQLLVNFETDSMALEDFLLHYCNQFPHFSLIVFWYLQAFLFELRNEPKSYSFQTVRKFINKLQNILFNVETSFHIRGPEFRENMQPALILCGSVASAFSSPLVNEYALPIVRSQGKQQKSFVFKLASFQKSLTRNLTMKNQRLSADAITPVISDDDSKVSNRIQESQRLKTKYSKKKISAALQLDDSENYTTDEEELGYVQTLSRPKIREMKYTEVEENLKINTIIRSKKNRSKTTVNSISFFSDTDQSASMEEYNRSAQSLPELVRTRSRLDLYSSESEAALGTSRNSAELIISKKKFMGSEVKTRPYKELLKILQVNYSKKETSFIMSLQNISLRLSSVPKVARLSALRAELSIINESILPSEIDIPQLLPVTSNKNKKFHKILKLNINEACVLNSAERVPYLLLIEYLSDEIDFNPFSDQNQKIINDCVRKPEVKPNDQISGDDDTSVVSSIQEEMFLDNNASENYNEDGDLGEISLLHSRSSSRDWAKSTPGSPVARSSQEDEKFYGNVSSTTGGTIESSVLADQMRIASLMLQQLESSGQSNTQQFVSIRNRIIESMISLQDQFDFIDYETLKELKTDEQDAGKRKLENDFKLAEDWNEKKHRIRKSSIYGHLENWDLCSVIVKNGDDLPQEAFACQLISLISNIWKKHKVDFWTKRMKILITSANAGLVETITNAMSIHSIKKSLTELSIENGENAKGRIFTLKDYFQKLYGSVDSSKYVKAQENFAISLASYSIICYVLQIKDRHNGNIMLDHEGHIIHIDFGFLLSNSPGSVGFEAAPFKLTSEYVEVLGGLESKAYLKFVDTCKNCFKALRKEWGQIVSIVELMQKGSSLPCFNNGDNTSVLLQQRLQLHLSDEEIDSFIEVYLIEKSVGSMYTRLYDQFQMITQGIYS",
    "output": "Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,-trisphosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNITLFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRRRHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSRTIPDPKLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTNYTIAGMVASQCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKSHGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVDTHHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIATFINKIKASPWFKDTVIVVSSDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNYLGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGSHFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELALSTDWCVSQGQLGGQQIVQHVDKAIWKGKTAFKDTVIDMARYKGNVDTLKIVDNDIRYKADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITAKAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGNILGHSPRKLGIGMVEIKVVEREG",
    "output": "Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVAAAVEELKTLSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKGLIAKKLGMTQIFAEDGKRIPVTVVQAGPCVVLQKKTSATDGYDAIQVGFLSQEARKVTKPMLGHIKAAGQGAFAHIREFRLDDVDRYNVGDVISADAFEVGEYIDVTGTSIGKGFQGVIKRWGFRGGRSSHGSCFHRAPGSIGSSAYPSRVFKNKKMPGQLGNERVTVQRLQVVRVDAADNILLIKGAIPGAKNGIVLVKDTVKPR",
    "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNDREPNQKESKESVNDAVPRARKVDDQQLRVSKIRDGTVIDHLTAGEALNVLAILGIDGSSGEGVSVGMNVISDRLGRKDIVKVEDRELSQSEVDVLAVIAPEATINIIRDYAVVDKKRIERPTAVTGLLFCPNRNCITNANEPINTRFIVLDEGLQCDYCGSIVRESEVPTYLDVA",
    "output": "Involved in allosteric regulation of aspartate carbamoyltransferase."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVSVINTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHSGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWREEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNMWSPKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASITEGQQNEQ",
    "output": "Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSRVIVKGLPIYLKEDRLRDLIEKRLTQKHQSTDVQSYLSDVKLMKNRDGESRRFAFIGFRDEEDAFDCVNYFNGTFVDTSKIEVSMAKSFADPRVPQPMREKRREALKRLREREELLLADKKDSQKKQKSDSNNDGGKKHDIDAEIAKNKQLQEFINTMKPSSQVTSWETVQSSKTQGEDEEAADDEVGEMSSNPLLSQALALKGNSRDADEDTDMFKLPGNESDDEYVSLNGGSNNANTDEPEPQMMSLDTFDTAGPTSTDDMAKDEAVSDLDWLKNRRVRIKDGADTPVSKQQQQPDTEQQQPEETEVETSQESEEEKSLKKIRETGRLFLRNILYTATEDDFRKLFSPYGELEEVHIAVDTRTGQSKGFAYVLFKNADNAATAFVELDKQIFQGRLLHILPADAKKSHKLDEFDLKNLPLKKQRELKRKANSAQQTFSWNSLYMNQDAVLSSVADKLGMKKSELIDAENSSSAVKQALAEASVIGDVRKFFETRGVDLTKFAQLKNSERDDRVILVKNFPYGTTREEIAELFLPFGKLQRLLLPPSGTIAILQFRDVPAARAAFSKISYKRFKDGIIYLEKGPSDCFTRDAQGDELVESETDIQKATAKEAKISGADLLEAQSLPAADKDDHDDDDDDDDVQAGPTVSIFIKNLNFSTTSQQLTEKFKPFNGFVVAQVKTKPDPKQPGKTLSMGFGFAEFKTKEQANAVISAMEGTILDGHKLQLKLSHRQGTSTTNASSKKKKKNQGKIIVKNLPFEATRKDVFELFSSFGQLKSVRVPKKFDKSARGFAFVEFLLPKEAENAMDQLQGVHLLGRRLVMEFVEQDPEDVEQQIEKMTRKVKKQVNTTKIANMRNSGKRKIDLDEDDENDGLQG",
    "output": "Involved in pre-rRNA processing."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFAVIKTGGRQYRVVPDDVLEVGKIEGEVGTIVQLGEVLMLGGDTPQLGLPTIAGASVAAEVLDHKRGPKVISFKKRRRKNSKRKRGYRDEITVLRITEILADGKKPSVGPRPKRVKAEPAPAADAAE",
    "output": "This protein binds to 23S rRNA in the presence of protein L20."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGSLGAILKHPDDFYPLLKLKIAARHAEKQIPSEPHWAFCYSMLHKVSRSFGLVIQQLGPQLRDAVCIFYLVLRALDTVEDDTSISTEVKVPIVMAFHCHIYDNDWHFSCGTKEYKVLMDEFHHVSNAFLDLGSSYKEAIEDITMRMGAGMAKFICKEVETIDDYDEYCHYVAGLVGLGLSKLFHASGAEDLATDSLSNSMGLFLQKTNIIRDYLEDINEIPKSRMFWPRQIWSKYVDKLEDLKYEENSGKAVQCLNDMVTNALLHVEDCLKYMSDLRDPAIFRFCAIPQIMAIGTLALCYNNIQVFRGVVKMRRGLTAKVIDRTNTMSDVYGTFFDFSCMLKSKVDNNDPNATKTLSRLEAIQKICKNSGALTTKRKSYIIENESGYNSTLIIILFIILAILYAYLSSNLPNSL",
    "output": "Component of the triterpene saponins (e.g. ginsenosides or panaxosides) and phytosterols biosynthetic pathways . Catalyzes the biosynthesis of squalene (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHDKILILDFGSQVTQLIARRVREAHVYCEIHPNDVSDDFVREFAPKAVILSGSHASTYEDHQLRAPQAVWDLGVPVLGICYGMQTMAVQLGGKVEWSDHREFGYAEMRAHGHTRLLDGIEDFTTAEGHGMLKVWMSHGDKVAELPPGFALMASTPSCPIAGMADEARGYYAVQFHPEVTHTVKGRQIIERFVLQIAGAKPDWIMKNHIEEAVAKIREQVGDEEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRLNEGKMVLDMFEGRLHAKVVHVDASDQFLGHLAGVTDPEAKRKIIGREFVEVFQAEAKKLSKAKWLAQGTIYPDVVESGGTKTKKATTIKSHHNVGGLPETLGLKLLEPLRDLFKDEVRELGVALGLPPEMVYRHPFPGPGLGVRILGEVKREYAELLRRADAIFIEELRNTTATAQDAAAGLCGEADVGKSWYDLTSQAFAVFLPVKSVGVMGDGRTYDYVTSLRAVQTTDFMTAHWAHLPYALLGRASNRIINEVRGINRVVYDISGKPPATIEWE",
    "output": "Catalyzes the synthesis of GMP from XMP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQVILLQRVAKLGQMGEVVNVKDGYARNYLLPQGKALRANESNIKSFEARKAQLEAQNLETKKEAAAVAEKLDGQSFVVIRSASDAGALYGSVTTRDAADAATEAGFTVDRGQVVLDRPIKELGLHTVTVTLHPEVAVKITLNVARSPEEAELQASGKSIQELAAEAEAAADFEIAELFDEIGAASQDE",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSRLRIFADTNPATPEFDSRDGDAIASELKKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDSTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYAPEKPHKAS",
    "output": "Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "GVDSSFLRL",
    "output": "FMRFamides and FMRFamide-like peptides are neuropeptides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARIGESVDLLKCSFCGKSQKQVRKLIAGPRVYICDECIELCNEIIEEELTEVTEADQTELPRPKQVYDHLQEYVIGQEPAKRSLAVAVYNHYKRIRAGVSGHTLSLAGAEGDEEAIEVAKSNILLVGPTGSGKTYLAQSLAKKLDVPFAVADATSLTEAGYVGEDVENILLKLIQAADFDLKKAEQGIIYIDEIDKISRKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPQQEFLHIDTTNVLFIVAGAFAGLEEIVQQRTGKKGIGFGAPIRDTADVDIAGQVQPEDLLKFGLIPEFIGRLPVVATLSKLSVADMVRILTEPRNALVKQYRKLFQLDGVELTFDPQALEAIAELALERGTGARGLRAILEDILMPVMFDLPGREDVAAVLVTEDAVAKLADPEIFTHEMIEAERRRHKSA",
    "output": "ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDPPSVRSKITEIEGDLFHAPDGAALIHACNCQGSWGKGIAKAFKDKYPAAFAIYRSHCQNLLSSPRYMFEPDLQSEESHARSSRDVRLPEGTALIIPPQKRDSEANGKKHWIICLFTSRGFGRAVSPPDVIVRNTELAVADMTRQLAELQTDQSSREESVGELWSCRFNAGLFGVPWERSRRVLEDAGLEVTVVRPHGG",
    "output": "Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKKEVSASKPGNTKKDNVLLKKRKQQAVEKEEAEKEKEEGVSEDEFNVQGLIDPESDSDDEGAAAAEEEEEEEEQQQDVKELDLDKGEVISSDSDAEDFDSEEELNKLLGEEDDPSDYSSVGFSDEPKEDGDEQDEQDAFAAADAATDDDAFGDVKLKNLSITDPSKLEVRTKFSDGTPRIIKPEIEPVYDSDDSDAENFNTIGNIPISAYEEMPHIGYDINGKRIMRPAKGSALDQLLESIDLPQGWTGLLDQNTGAPLKITDEELELIRKIQQQENTDENINPYEPLNDWFTKNQEVMPLTAVPEPKRRFVPSKHEAKRVMKIVKAIREGRILTPEKAKELKEKETEEMNYDLWQNESEVPDHIMNLRAPKLPPPTNEESYNPPEEYLLNEEEKQKWLEQDPVDRERNFIPQKYSSLRLVPGYQDSVRERFERSLDLYLAPRLRKNKLNIDPESLIPELPSPKDLRPFPIKCSTVYEGHTGKIRTLSIDPQGLWLATGSDDGSVRIWEVLTGRQVFKAQLVNKEHNGEDHIESLEWNPNAQTGILAVCAGENIYLLVPPIFGFEIENTGKLRIESGWGYDTFGNTKQDLKVKGEDTKGDLDDDEEEEEEEEDDDDDEGQGKVKAHNSTAPAKKDVAKWINPNSSQQAMGISAIIQCRRTVKKISWHRKGDYFVTVSPDSKNTAVLIHQLSKHLSQSPFRKSKGVIMDAKFHPFKPQLFVASQRQIKIYDLAQQTLLKKLLPGVRLLSTIDLHPRGDNLLAASYDKRVLWHDLDLAATPYKTLRYHEKAVRQIKYHKGSLPLFASASDDGIIHVFHGTVYDDLMTNPLLVPLKKLSGHKVINQIGVLDIVWHPKEAWLFSAGADGTARLWTT",
    "output": "Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPDAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA",
    "output": "Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKNFDKFSTNEEFSSVYKVGKKWHCEGVIIFYLNSYEKKIAVVASKKVGKAVVRNRSKRILRALFAKFERYLQDGKYIFVAKNEITELSFSRLEKNLKWGLKKLECFK",
    "output": "RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKFVDEATIEVIAGKGGNGVASFRREKFIPKGGPDGGDGGRGGSIYAVADRNINTLIDFRYARLHRAKNGENGRGSDQYGAAAPDITLRVPVGTVVHDADTGEVLFDLDRHDQKVTLAAGGAGGMGNIHFKSSTNRAPRQWTPGKEGEQRRLRMELKVLADVGLLGLPNAGKSTLISRISNARPKIADYPFTTLHPNLGVVRTSPSRSFVVADIPGLIEGASEGAGLGHLFLRHLARTRVLLHLVDISSPDPEADPIEQAVVDANAIVEELRRYDPELAAKPRWLVLNKLDMVPDAQDAQQRFCAEFGWTGPVFAISGLNGEGTQDLIWALQDYLDAEKRKDQDAQDQADGTYVFEDPRFDASRGGAAPATPPGGDE",
    "output": "An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKVGVVGASGYVGGETLRLLVNHPNVEITMVTSRQHVGEYLHRVQPSLKGFTDLTFSELDYDKLTDKCDLVFTAVPHGTATEIVKALYDRGIKIIDLSADYRLHDQDAYDKWYGWEHPHPDYLNKSVFGVPELHREEIKKAQLVSCPGCMAVTSMLALAPLIRNNIIDTDHIVVDSKIGSSGAGSGSGTAHAMRAGVIRPYKPAKHRHTGEIEQELSEIAGKKIHVSMSPHAVDVVRGILCTNHTFMQKDMEEKELWKLYRQTYGEEKFVRLIRDKKGLYKFPDPKFLVGSNFCDIGFDLDEDNNRLIALSASDNLMKGAAGSAIQNMNVMCGFDEMDGLRYTPLTPV",
    "output": "Involved in both the arginine and lysine biosynthetic pathways."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MWLKPEEVLLKNALKLWLMERSNEYFVLQRRRGYGEEGGGGLTGLLVGTLDSVLDSTAKVAPFRILHQTPDSQVYLSIACGANREEITKHWDWLEQNIMKTLSVFDSNEDITNFVQGKIRGLIAEEGKQSFAKEDDPEKFREALLKFEKSFGLPEQEKLVTYYSCSYWRGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDAISKLEKTSTVILTESIHVCSQGENHYFSMFLHINETYLLMEQLANYAIKRLFDKETFDNDPVLDDPLQITKRGLEYRAHSEQFKAFFRLPKEETLKEVHECFLWVPFSHFSSHGKMCISENYICFASQDGNLCSVIIPLREVLAIDKTDDSNRSVIISIKGKTAFRFSELKDFEQLVAKLRLKCRAASTQDDVSTEVAVSSDSTGPSENFEEQPLTCPKECSKTVNTEALMTVFHPQNLENLDSKMLKEKMKEQSWNILFSECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPGYYAEVVEQSLGTSNLATEEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQAVFEELIRDHLPQLTDHMTDMTFFSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLTCKDDAEAVTALNRFFDNVINKDSPLPSNVQQGSNISNEKSDHTKVDITDLIKESNEKYGSIRYEDIHSMRCRNRLYVIQTLEETTKQNVLRVVSQDVKMSLQELDELYVIFKKELFISCYWYLSCPGLKHHDPSLPYLEQYQIDCQQFRVLYHLLSPWAHSANRDSLALWTFRLLDENSDCLINFKEFSSAIDIMYNGSFTDKLKLLFKLHIPPAYTEVMSKTSSKGDELSTEELLYFSQLQVSKPADEKETESGRNSPEKGKGKIDIQAYLSQWQDELLKKEETIKDLPRMNQSQFIQFSKTLYNLFHEDPEEESLYQAIAIVTNLLLRMEEVGRKLHSPASSASTARDSGPSEGNAESSVKKDLPSPREEHQWSFAFEQILASLLNEPALVRFFERPLDLKAKLENAKSSQLRSRTKM",
    "output": "Involved in vesicular recycling, probably as a RAB11B GTPase-activating protein."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSFLKTSDPAVYNAIMQETTRLKETIDLIASENYTSKAVLEAQGSVFTNKYAEGYPGKRYYAGCEYADAVEELAIDRAKTLFHAEHANVQPHSGAQANMAAYFAMVKPGDTIMGLTLSHGGHLTHGSKVNFTGKLYHVIEYGLNAETERIDYDNLEKLAMEHRPRMIVTGASAYPRILDFERFRAICDKVDAKLMVDIAHIAGLVAAGLHPSPVPYADVVTSTSHKTLRGPRGGFILCKEQYAKAIDQAVFPVMQGGPLMQVVAAKAVAFQEAMQPGFVTYQKKTLENTQVMAEELRKLGLRLVSGGTDNHLVLVDLSPIGVNGYDAQLALRRAGIVINRNTVPFAENQTANVPAGIRLGCPAATSRGFGPAEIRQTVGWIGKVLKNIGNEDVEKQVLAEVIHLCRKFPVPGIDI",
    "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSMRSQYCGLVTEELLGQSVSLCGWVSRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFKAAEGVRNEFCLQIKGVVRGRPEGTTNAALKSGKIEVLCHELIVLNPSITPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDSLGFIDIETPMLTKSTPEGARDYLVPSRTNPGQFFALPQSPQLFKQLLMVANFDRYYQIVKCFRDEDLRADRQPEFTQIDCETSFLSEQEIRDLFEDMIRHVFKETIGVTLDEKFPVMLYSEAMRRFGSDKPDLRVKLEFTDLTDAVRDVDFKVFSTPANTKDGRVAAIRVPKGGELSRGDIDSYTEFVRIYGAKGLAWIKVNEVAKGRDGLQSPIVKNLHDEAVKAIIERTGAQDGDIIFFAADRAKVVNDSLGALRLKIGHSEFGKANGLVETGWKPLWVVDFPMFEYDEEDNRYVAAHHPFTSPKDEHLEYLETDPARCLAKAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKINAEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIVTMMAGADSIRDVIAFPKTQRAQCLLTQAPSEVDERQLRELHIRLRQPEPKV",
    "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSALTESFGPVPSAKSKPPAARKPWYKLLYLQVLVAIVLGVLLGWLSPHIATNEWVKALGDGFVKLIKMVIAPIIFCTVVSGIAHIQDARKVGRVGVKALLYFEVVSSFALLIGLVVGNVVQIGHGLGATGDAAAVSKYVKQAEAQHSVDFVLNIIPDSVVGAFAKGDILQVLLFAILFGFALMTLGERGHRLRDVIDDASHAVFGVIAIVMKAAPVGAFGAMAFTIGKFGPAALGNLIGLIAVFYITAALFVVLVLGLIAKIVGFNIFKFLKYIKDELLIVLGTSSSESALPQLMEKLERLGCSKSVVGLVVPTGYSFNLDGTNIYMTLATLFIAQALGVDLTWTEQLTILLVAMLTSKGASGVSGAGFITLAATLSVVNPALVPGMAIVFSVDKFMSEVRALTNITGNGVATVFVSWWENELDHDKLAAALNKTIDPSDIETAVTTG",
    "output": "Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPKKAVVLLSGGLDSSTVLAYALNKGFEVYAISFDYGQRHLKEMKSSEAISKFYNVDRKIVKVDLRSIGKSALTDNIEVPSRDISTIEEEIPVTYVPARNTIFLSIAAAYAESLGTNEVFIGANAIDYSGYPDCRPEYFNAMENALSLGTKIGLKEKFHINVPLQYLSKADIVKLGVKLNVPYELTWSCYKGEEEACGECDSCQLRLKGFMEAGFADPLKYSKYPEFYSKNLVKLRPLKRR",
    "output": "Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGEVKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFFRQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGSLGINQEEQ",
    "output": "May play a role as a negative regulatory factor in CD4-dependent T-cell activation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "EVKYDPCFGHKIDRINHVSNLGCPSLRDPRPNAPSTSA",
    "output": "Exhibits vasodilator, natriuretic and diuretic properties in animal models and human tissues. Acts by stimulating cGMP via the natriuretic peptide receptor A (NPR1). Is a poor agonist of the atrial natriuretic peptide receptor B (NPR2). Is not degraded by neutral endopeptidase (NEP/MME). Binds to atrial natriuretic peptide clearance receptor (NPR-C/NPR3), which may be responsible of the removal of DNP from the circulation. Increases calcium uptake and induces histamine release from rat peritoneal mast cells. Increases calcium-activated potassium (KCa) current in gastric antral circular smooth muscle cells by increasing cGMP production and activating inositol trisphosphate receptors (IP3Rs)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFETVIGLEVHCQLNTKTKIFCSCSTSFGDEPNTHVCPTCLALPGALPVLNKEAVKKAISFGKAINATVNKKSVFDRKNYFYPDLPKAYQISQFTIPIVEKGELFIKVGGEIKRIGITRAHLEEDAGKNNHETNKSLVDLNRAGTPLLEIVSEPDLRNSDEAVAYLKKLHSILRFLNISDANMQEGSFRCDVNVSIRPKGDEKLYTRVEIKNLNSFKFIQKAIEYEVERQILSWEDGKYDEEVYQETRLFDTNKLVTKSMRSKEDSAEYRYFPDPDLLPVIIPDKMMEEASVLPELPDEKKARYVKDLGIKESDAEVIISSYEMARYFEDLIEAKNSPKLAVTWLCVELLGRLKNGVTIETSPVDSKKLSNLINRIEDGTISQKAAKDVLDYVMEHDEDVSSVIEKLGLKQVSDDSAILAIIDSVLSANSDKVAEFKSGKDKLFGFFVGQVMKEGKGAFNPSKVNDLLKSKL",
    "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSSGGLLLLLGLLTLWAELTPVSGQDRPVKPGLCPPRPQKPPCVKECKNDWSCRGEQKCCHYGCIYECRDPIFVK",
    "output": "Damages membranes of susceptible bacteria. Has no hemolytic activity. Not toxic to mice. Does not inhibit the proteinases elastase and cathepsin G."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAFHCQRDCYATELLTEVVSCHPAQLKLENGGKKNTVSGFNVLLKDTVLFPEGGGQPDDRGFIGEVPVLRVIRQGPDAVHFVASPLDPATEVLVKIDWNRRFDHMQQHSGQHLVTAIADSLYGFKTTSWDLGRQRSVIELDTPLVTTEQLEAIEKIANQKIREHVPVHVRLITVDDPEFDMVRSRGLPDDHAGPVRIIDIEGVDANMCCGTHVRNLSDLQMIKILGTEKGKKNKTNLIFLSGERVLKYVSRSYNTEKTLTSLLKNGPEEHIEAVDKLQKSVKALQKNNLTLLRDLAVLTAENFKSKADRGKFFSLHRKEGDNEFMNIIANVIGTEDTLLFLTIGDEKTSGLFLLAGPPGIVEKFGPRVCEILDGKGAGKCGRFQGKANKMSQRAEVEVLLQKVISSVEITQE",
    "output": "Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "ERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRIIEMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWNRNGPTTSAVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKIAPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGIRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKKEEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTPSTEMSLRGVRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQDPTMLYNKMEFEPFQSLVPKAARGQYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAI",
    "output": "Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription. Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA. Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPRLSRRQLLKTAAISTALSTVPAPLLAASREKLVVPPLIEVRRGRPIVLTMQETNYPLDGSHNVTVWGFNGNYLGPTIKIKSGSFAKLNYHNNLPQSVALSIQGLQASGELFGGAARVLKKGESWAPIVPIEQPAASCWYRSATLANSAYQTYRGLAGMWLIEDEQSLKANLPNKYGVDDIPLILQDMEFNNDGLQLFKQNQPHFVGNRLLVNGIEAPYLDVARGWIRLRLLNASLARAYDLRLDNDQEMLLIAQDLSFLPKAKSVKSLVLSPGERAEILVNMNEIDNVSLISGSKRSLYEKIKNMLFSGDELANNTVLELRAQGQLSAFNKQPNLTFETDAPAILQQAVAQTREFNIDVTNGLINQRRFDPRKVDVMARKGTIERWILNASLPVGFTIQGAKFVVESQGEHQLQAEELAWKDTVWVKNKTQILVKFDQASSGNFPFLFGVSNLMLEDMGCLGVLMVQ",
    "output": "Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKIIKISPRGYCYGVVDAMVIARNAALDKSLPRPIYILGMIVHNKHVTDAFEEDGIITLDGPSRLEILDQIDSGTVIFTAHGVSPEVKQRAKEKGLTTIDATCPDVTKTHDLIEAKKSEGYHVIYIGKKGHPEPEGAVGIAPDIVHLIEKADDLKTLEIPTDKILVTNQTTMSQWDVQHLMEDIKKKFPTAEFHKEICLATQVRQEAVAKQADVADLTIVVGDPKSNNSNRLAQVSQEIAGTKAYRVADVSEIQLEWLQGVEAVAVTAGASTPTPITKEVIAFLEQYDPTNPATWERKRNVPLQKILPRVKVKKQ",
    "output": "Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQLVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKVLAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRFTEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTLLGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMVPPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTEIDKGSAYGNSGSKQKLND",
    "output": "Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDKEEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKENGIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFDDLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNEVDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQGLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK",
    "output": "Acts as a chaperone."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVVIGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVALAQDWRKDPTLQKLEAMMIVMDEHDLLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNIDIFTNHNVIVESF",
    "output": "Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEAVPSSDSYPAVENEHLQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKP",
    "output": "AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEATSVFRPKLGSQFSLPSTTNLFPLRKLYGFPLTSFPGKPIKRIRLKATNTLTFDDKERTRKFKKLPLSEWTHYFHSIPLDISEMDALKEEIDELKPKVKNTFMSSQGSDSTKTKILMIYLFVSLGLAYHFEEEIYETLKEGFENIEKIMAGEEDLYTVSIIFWVFRRYGHYISSDVFQRFKGSNGSFKESLIGDAKGMLSLYEAAHLATTKDYILDEALIFTSSHLETLVATGTCPPHLLARIRNALSICQHWNFEVLVPLDFIPFYEQEKDHDEMLLKFAKLSFKYLKLIYLQDLKILTKWYKKLDFPSKFPPYFKDRCVENYFFVLPVFFEPQLSSARMLLTKGFILLGIQDDTFDRYASISEAESLGNSLKRWAPDHSMDKQPEYLKSVLKVILDTFQEFEKELSPEGRSYSVKYTIEEFQASSKANVELAKWAQVSHVPSFEKYMEVGQMEITACVTVAYILMSMGKTGTKEAFEWLKSRPKLVQSLCTKGRLMNDIAGFEDDMSRGYVVNAVNCYMKQYGVTEKEAFKELRKMVVNTHKTLNEEFLTTTCVSHYVLRETMDFARMIIVTYNGYEGFTRPDEGKIEEYMTSLFVDHTLKML",
    "output": "Involved in terpene biosynthesis in roots. Possesses diterpene (C20) synthase activity in vitro. Does not seem to be involved in sesquiterpene (C15) biosynthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPITFKKIDKEDFLEIRKNFLENYKNLDDFDLNTAIRFHKSLPDHKNFQKKIEQSVQDNKIMTQAHSKETLLEDLIKNLNTFYRVGQADFLSIIIDSHTRENHYDNAKVILEDSIKSNKSLLNGFPLINYGTKLARKIINDVEVPLQIKHGSPDARLLVEVALLSGFSAFDGGGISHNIPFSKSISLKDSLENWKYVDRLVGIYEENGIKINREIFSPLTATLVPPAISNSIQILETLLAVEQGVKNISIGVAQYGNITQDIASLLALKEHIQFYLDTFSFKDINISTVFNQWIGGFPEEELKAYSLISYSTTIALFSKTNRIFVKNIDEYAKNSLGNTMINSLLLTKTILDIGNNQKINNYEEIIFEKEQIKKETAQIIAKIFSRCDGDLRKAIIEAFEYGVLDVPFAPSKYNLGKMMPARDSEGMIRYLDIGNLPFCPLIEEFHNKKIKERSMKENREINFQMTIDDIFAMSQGKLINKKSRE",
    "output": "Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MYKQIFLCLIIAALCATIMAEASALADADDDDDKRYVRGMASKAGAIAGKIAKVALKALGRRDS",
    "output": "PGLa and PGLa-H display a broad-spectrum of antibacterial activity against a range of Gram-positive and Gram-negative bacteria. PGLa also displays antifungal activity against C.albicans ATCC 14053. PGLa-H shows moderate antibacterial activity against the multidrug-resistant methicillin-resistant S.aureus (MRSA) but exhibits very little hemolytic activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKLSTVLCCYLLLLGLFAPEIISDSPPLQDVCPMAPQGERKLFMNGFFCKSPSTIMASDFKTLLLNHAGDLDNMVRSSANIITATEFPGLNTLGISMARTDIAVSGAVLPHSHPRASEMMFVHSGSVVAGFFDTKGKLFQKTLAEGDVFIFPRGLVHFIMNYGFGLATTFSVLNSQNPGVVGITHAMFAPDSEVAEGLMARMLSFRDMGMDDSSSVDSPWFY",
    "output": "May play a role in plant defense. Probably has no oxalate oxidase activity even if the active site is conserved."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKARYRGAVSSSLATTERLKSHGIKVFDLNEIESLQVYVDGADEIDASGAMIKGGGGALTREKIVASVADTFVCIADASKRVPVLGAFPLPIEVVPMARTAIGRRVTALGGVPVLRVTKDGAPYITDNGNEIIDVKGLQIADPRGFEAQVNAWPGVVTVGLFAERGANLCLLGTPNGVETIVYPA",
    "output": "Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRTGIIAQKIGMTSVFNDKGERIPLTLVKVDDCQVVGHKTLEKHGYNALVIGIKDKKISRVTKPMKQVFANAKISPKTKLKEFRISEGNFIDIAANLEVDHFMAGQFVDITATTIGKGFAGSMKRHNFRGLEASHGVSISHRSHGSTGQRQDPGKVFKGKKMAGHMGCNQVTIQNLKIFAVDRERKLIMIRGSIPGHKNSYLSIKDAVKKNSITV",
    "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYQSLSKRGGKA",
    "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKVALVYNEKVETLAVVKALEKLLDSRKIEIDPENPDVVITIGGDGTLISGFHKYQNLVDQIRFIGVHTGHLGFYTDWRNFEIGKMVDNLTKKQPSSASYPLLELIITTGSGEKKKLLALNEATIKRVSKTLKADVYIRDQFFESFKGDGLCVSTPTGSTAYSKSLGGAVIHPRLKALQMTEIASINNRVFRTLSSPIVIAPDEWITIKPESDDHYVVTYDGYEFNHKHIKKIEYRISQHVIRFDKYQHTHFWNRVEDAFIGQPKNK",
    "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNLSQFEQFDLSPELLKALEKKGYSRPTAIQMEAIPAAMEESDVLGSAPTGTGKTAAFLLPALQHLLDYPRRKPGPPRILVLTPTRELAMQVAEQAEELAQFTHLNIATITGGVAYQNHGDVFNTNQDLVVATPGRLLQYIKEENFDCRSVEMLIFDEADRMLQMGFGQDAEKIAAETRWRKQTLLFSATLEGELLVDFAERLLNDPVKVDAEPSRRERKKINQWYYHADSNEHKIKLLARFIETEEVTRGIVFIRRREDARELSETLRKRGIRSAYLEGEMAQTQRNNAIDKLKSGIVTVLVATDVAARGIDIDDVSHVMNFDLPYSADTYLHRIGRTARAGKKGTAVSFVEAHDYKLLGKIKRYTEEILKARILAGLEPRTKPPKDGEVKSVSKKQKARIKEKREEKKKTEAKKKVKLRHKDTKNIGKRRKPSNSNV",
    "output": "DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSTIRCDIVSAEQEIFHGEATFVVATGELGELGIAPKHAPLITRLKPGKVVITTVNGEQLDFAISGGILEVQPQVVTILADSAIRADTIDEVAVRKAKEEAERILANRGETIDVAKAQQQLVEAVVQMQALERLRRTVKH",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRLDENEGAFTIPEFGKIQFEGFCRFIDQGLMEELHNFPKIEDTDKEIEFSLFGNEYELAEPFIKERDAVYQSLTYYSELYVPARSIRRNSRKIQKQTVFLGNIPLMNSHGTFVVNGIYRIVVNQILISPGIYYRSELDHNRINYIYTGTLISDWGRRSKLEIDVGERIWARVSRKRKISIPVLLSAMGLNLEEILDNTHYPKRFLFLLKKKERWEREEYLWSREKAILEFYKKLYCVSGDLVFSESLCKELQEKFFRQRCELGKIGRRNLNQKLNLDIPENEIFSLPQDVLAAVDYLIGVKFGMGTLDDIDHLRNRRIRSVADLLQNQFRLTLGHLEDTVRRTIHGATKRRSTPQNLVTSTLFKNTFQDFFGSHPLSQFLDQTNPLTEIAHGRKLSHLGPGGLTGRTASFRTRDIHPSYYGRICPIDTSEGMNAGLVSSLSIHAKIGDCGSLQSPFYKISERSREEHMVYLLPGEDEDEYYRIATGNSLALNQGIQEEQITPARYRQEFIVIAWEQIHFRSIFPFQYFSVGVSLIPFLEHNDANRALMGSNMQRQAVPLFRPEKCIAGTGLEGQAALDSGSVAIATQEGRIEYIDAVNITSSINGDTVRTESVIYQRSNTNTCTHQKPQVRQGECVKKGQILADGATTVGGELSLGKNVLVAYMPWEGYNFEDAILISERLVYEDIYTSFHIVRYRIEICMTSQGPERITREIPHLDAHSLRHLDENGLVMLGSWIETGDVLVGKLTPQTTEESLCTPEGRLLQTIFGIEVSTARESCLRAPIGGKGRVIDVRWINRVDDSGDNAETVHVYISQKRKIQVGDKVAGRHGNKGIISIILPRQDMPYLQNGIPVDMVLNPLGVPSRMNVGQIFECLPGLAGNLMNKHYRITPFDEKYEREASRKLVFPELYKASEQTANPWVFEPDHPGKHRLIDGRTGAVFEQPVTIGKAYMSKLSHQVDEKIHARSSGPYARVTQQPLRGKSKRGGQRIGEMEVWALEGFGVAYILQEMLTLKSDHIRTRNEVLGAIITGGPIPKPDTAPESFRLLIRELRSLALELNHAIISEKDFQIDREEV",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MYVFPKISLRPEVENYLKESFLNEEAVSASSRQEAERKFETLLLRLSHPPSMTTVRVNTHLGSVQHVRGLLLEELQKQFGESSIPVVQHPALPDVLLIPMTGPRKNIERQQGEVIVGAQCGNAVLRGAHVYVPGIVSASKFMKAGDVISVYSDINGKCKKGAKEFDGTKVFLGNGISELSRKDIFNGLPDLKGIGIRMTEPIYLSPSFDNVLPSYIFLQNLPSTVVAHVLDPQPGEKILDMCAAPGGKTTHTAALMQDKGEVIALDKILTKVNKLKQNASLLGLHSIRAFCFDATKALKLDTTDGIEGGPPFLPESFDRIILDAPCSGMGQRPNMACTWTLKEVTSYQPLQRKLLHVAVQLLKPGGVLVYSTCTITLAENEEQVAWALRTFPCLQLQPQEPQIGGEGMVGAGLTLEQLKQLQRFDPSVVPLQNMDTDSLGEARREDMIWLANKDCIGFFIAKFLKCQSTKAKVSQK",
    "output": "S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in tRNA(Thr)(TGT) and tRNA(Cys)(GCA). In vitro also methylates tRNA(Thr)(AGT). Methylation requires, in the acceptor stem region, the presence of the 3'-CCA terminus, the target site C72, the discriminator base U73, and the second and third base pairs (2:71 and 3:70) in the tRNA substrates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTVPAPSQLDLRQEVHDAARRARVAARRLASLPTTVKDRALHAAADELLAHRDQILAANAEDLNAAREADTPAAMLDRLSLNPQRVDGIAAGLRQVAGLRDPVGEVLRGYTLPNGLQLRQQRVPLGVVGMIYEGRPNVTVDAFGLTLKSGNAALLRGSSSAAKSNEALVAVLRTALVGLELPADAVQLLSAADRATVTHLIQARGLVDVVIPRGGAGLIEAVVRDAQVPTIETGVGNCHVYVHQAADLDVAERILLNSKTRRPSVCNAAETLLVDAAIAETALPRLLAALQHAGVTVHLDPDEADLRREYLSLDIAVAVVDGVDAAIAHINEYGTGHTEAIVTTNLDAAQRFTEQIDAAAVMVNASTAFTDGEQFGFGAEIGISTQKLHARGPMGLPELTSTKWIAWGAGHTRPA",
    "output": "Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNRLTHCFNELKQRNTKALVTFITAGDPDLATTQAMIPLLQQAGADIIELGMPFSDPMADGPTIQLSSERALAASTTLERILAMVRAVRRSCQVPIVLMGYLNPIHAYGYERFANDAAEAGVDGVLVVDMPPEEAESFLNHANARDLQVAFLLTPTSTDSRIATVGRLGRGFVYYVTVTGVTGARQQVSTTLGGELAKVRAKISVPIVAGFGISTPQQAADVAAMADGVVVGSALVKLFQLHSGEELRQEVTRFVASLRQAIPGGAA",
    "output": "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASLKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSDGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKIKDDDTIVLVGFGGGLTWGAMTIKWGK",
    "output": "Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTSIPISVQGYKALEEELARLKSERPEIIQAIKEAREEGDLRENAGYDAARERQGMAEARIKYIESRMALYQVIDLDTLSGDKVIFGATVDLEDVDSGEAKTYTILGPDEADPSKGSISFLSPVGQALLGREEGDEVSVEIPRGRVTYEIIGVSFKGSKNLG",
    "output": "Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKNKTKKGGDSTIALNKKARHDYFIEDKYEAGLALQGWEVKSLRAGKAHIGDSYVLLQNGEAFLFGATITPLNVASTHVVCDPTRIRKLLLKKSELERLIGLVERQSYTLIPLSMYWSRAWVKVEIGLAKGKKEHDKREDLKEREWQRDKERMMKNKGR",
    "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFHSLLVKNFILIDELEIEFNKGLCVITGETGAGKSILLDAILFCLGYKTSNNIIKRGKDYAVVNIIFSLNEEIKNFLIQNFIEPEELLLVKCLQKAEGRKNFFINNQVVNKAIMQQLATYLFELHGQNNNISLLEANTQRDILDSYGNLLDFRAELSKCYQTWQNTRKEIAEITLKQNSIDQEIDYLSFATEELTKLNIQIGEEEKLANIRKDLQNKDKDLQLIKDVLEQINNPEINTSINRAEKLLARQGDNERFEAIATSLEEAYNNLEEARQGLSNLLDSFNYEEYNLEETEERLFLIKAISRKYNVPADELGIFLDKSLEQLGILKNKIANSNELKAQEMLLQKKYYELASDLSVKRLIAAKHLEESLHQELKQLKMAKAIFEIEIIAGKEPTASGNDDIVFKASTNPGMATEAINKIASGGELSRFMLALKTSLFDKMVKPSIIFDEIDVGIGGEVADKVGERLKKLSSVTQVIVITHQPQVAGKADLHIKIEKTQLEKETKVTVKALNLAERQEELARMISGKTITEASLKAAKELLHL",
    "output": "May be involved in recombinational repair of damaged DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPSIKLLVWCCLCVISPRLCHSEKLFHSRDRSDLQPSAIEQAELVKDMLSAQQFLAKYGWTQPVIWDPSSTNENEPLKDFSLMQEGVCNPRQEVAEPTKSPQFIDALKKFQKLNNLPVTGTLDDATINAMNKPRCGVPDNQMAKKETEKPTAAQSLENKTKDSENVTQQNPDPPKIRRKRFLDMLMYSNKYREEQEALQKSTGKVFTKKLLKWRMIGEGYSNQLSINEQRYVFRLAFRMWSEVMPLDFEEDNTSPLSQIDIKLGFGRGRHLGCSRAFDGSGQEFAHAWFLGDIHFDDDEHFTAPSSEHGISLLKVAAHEIGHVLGLSHIHRVGSIMQPNYIPQDSGFELDLSDRRAIQNLYGSCEGPFDTAFDWIYKEKNQYGELVVRYNTYFFRNSWYWMYENRSNRTRYGDPLAIANGWHGIPVQNIDAFVHVWTWTRDASYFFKGTQYWRYDSENDKAYAEDAQGKSYPRLISEGFPGIPSPINAAYFDRRRQYIYFFRDSQVFAFDINRNRVAPDFPKRILDFFPAVAANNHPKGNIDVAYYSYTYSSLFLFKGKEFWKVVSDKDRRQNPSLPYNGLFPRRAISQQWFDICNVHPSLLKI",
    "output": "Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLLEEDPSTLIAHTTQNFNITPDRHAVSRVAESLSTLQQARDLRLRESETNLKKLARTLNTLQSQHQEVTSSHSSAEHASLISRLDTQKFRVAKNVSDLEMETERLQTQLAELQARLQELELQGVDGGDASAAGGATSTGENNGNGSAGNGGQVRSVEDEVLLRLKVYRSLGIEIEREEQDGGEFTRAVVRNDRRGDVCVVNVDRHRFSRFFYANYFWQTL",
    "output": "Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRIGMICPYSFDVPGGVQSHVLQLAEVMRTRGHLVSVLAPASPHAALPDYFVSGGRAVPIPYNGSVARLRFGPATHRKVKKWLAHGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKSLTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVDSFASAARLDGYPRQGKTVLFLGRYDEPRKGMAVLLDALPKVVQRFPDVQLLIVGHGDADQLRGQAGRLAAHLRFLGQVDDAGKASAMRSADVYCAPNTGGESFGIVLVEAMAAGTAVVASDLDAFRRVLRDGEVGHLVPVDPPDLQAAALADGLIAVLENDVLRERYVAAGNAAVRRYDWSVVASQIMRVYETVAGSGAKVQVAS",
    "output": "Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM). Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEAIKKKMQAMKLEKDNAIDRAEIAEQKARDANLRAEKSEEEVRGLQKKIQQIENELDQVQEQLSAANTKLEEKKKALQTAEGDVAALNRRIQLIEEDLERSEERLKIATAKLEEASQSADESERMRKMLEHRSITDEERMDGLENQLKEARMMAEDADRKYDEVARKLAMVEADLERAEERAETGESKIVELEEELRVVGNNLKSLEVSEEKAQQREEAHEQQIRIMTAKLKEAEARAEFAERSVQKLQKEVDRLEDELVHEKEKYKSISDELDQTFAELTGY",
    "output": "Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSKFKSLLLLFGTLILLSGCSNIEIFNAKGPVASSQKFLILYSIVFMLVICFVVLGMFAIFIYKYSYNKNAESGKMHHNAIIETIWFVIPIIIVAALAIPTVKTLYDYEKPPKSEKDPMVVYAVSAGYKWFFAYPDEHIETVNTLTIPKDRPVVFKLQAMDTMTSFWIPQLGGQKYAMTGMTMNWTLEASQTGTFRGRNSNFNGEGFSRQTFKVNAVSQKDYDKWVKEVKGKKTLDQDTFDKQLLPSTPNKALEFNGTHMAFVDPAADPEYIFYAYKRFNFELKDPNFTSEENMFKDVSDKPLIPARKAQITNANYKRHGMKLMILGNDEPYNNEFKKDESKNAKEMKKISKDAQDQDNDDHGGGH",
    "output": "Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPLSYQHFRRLLLLDDEAGPLEEELPRLADEGLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSTVPVFNPHWKTPSFPNIHLHQDIIKKCEQFVGPLTVNEKRRLQLIMPARFYPKVTKYLPLDKGIKPYYPEHLVNHYFQTRHYLHTLWKAGILYKRETTHSASFCGSPYSWEQDLQHGAESFHQQSSGILSRPPVGSSLQSKHRKSRLGLQSQQGHLARRQQGRSWSIRAGFHPTARRPFGVEPSGSGHTTNFASKSASCLHQSPVRKAAYPAVSTFEKHSSSGHAVEFHNLPPNSARSQSERPVFPCWWLQFRNSKPCSDYCLSLIVNLLEDWGPCAEHGEHHIRIPRTPSRVTGGVFLVDKNPHNTAESRLVVDFSQFSRGNYRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARLSSNSRILNNQHGTMPDLHDYCSRNLYVSLLLLYQTFGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLFTAVTNFLLSLGIHLNPNKTKRWGYSLNFMGYVIGCYGSLPQEHIIQKIKECFRKLPINRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQSKQAFTFSPTYKAFLCKQYLNLYPVARQRPGLCQVFADATPTGWGLVMGHQRMRGTFSAPLPIHTAELLAACFARSRSGANIIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLSRPLLRLPFRPTTGRTSLYADSPSVPSHLPDRVHFASPLHVAWRPP",
    "output": "Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids. This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode. Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid. Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein. Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome. After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA). The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIVFYLSGDRVFSTDQNAINGLYNKRHFGKLVEGKLFLSLLEATYLVERGKIEVREGKRKLTVEELMNLGRERDELFDAKYLVYKDLRDRGYTVKSGLKFGSHFRVYRRGMDEHSQWLVWVLPENSRLSPNDITARVRVAHGVRKNMIMAIVDEDADVTYYKVEWVRF",
    "output": "Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRAVVQRVKRSKVEVDGKIIGEIGKGLNVLLGISVEDKKEDISYMKDKILNLRIFEDEEGKLNKSLLDVQGELLIISQFTLYGDCRKGRRPSFIKALGGEKARSVYNEFIDQCKDSVHNVQTGEFGADMLVSIENDGPVTIMVDSEKIF",
    "output": "An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MMGIEDIVLGLNVDRESAKRLYEIISKEDCSDVCRAAVLTAFHFKGVTREEFMGFLDAIYKPTVSVDATDIVGTGGDKKNTINVSTASAIVAASLGIPVAKFGNRSSTGAYGSADFMADAGYSFPRDVEAALHRLKSNNFVFMLAPTFIPEFKIFSTVRKRLGFPTLFNYLGPVLNPLAPKKRVIGSASTEMMDVYSYILNELGYQAIIIRGQDGMDEITPFNFTDVIYVDGSVEKYVVDGRSISNDVRYDKISSQDPSLIRKFNFMGLKGENEDAAKFIALNTAPVLILNKKAGNYEDAYRLALEAIKSGQAYEKLEAIMHENKGLRHN",
    "output": "Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRIALVVEYDGSQYHGWQAQTGLHTIQQAVEFALSKVADSSISVVCAGRTDTGVHATNQVIHFDCEKDRSIRAWIHGANTFLPKDICVKWGKEMPENFHARYSAVSRRYRYVIYNGAIRPGLLRGNVTWQYRQLDHRLMQQGGQCLLGENDFTSFRSVECQSNTPMRNIHQLQVTRHGDLVVLDITANAFLHHMVRNIAGVLIAVGSGKHPVGWVKDVLNAKDRKLGAETAPSYGLYLVQVTYPKEFGLLQNNPGPLFLWEK",
    "output": "Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGKKQVALPRALPPMPSTSIDEIPHSRPKKKKTKSNNNTPDDVLQNAGFTTSENNDPLSPERRKRKKKRFSIDAETSLTQNNPSIPVVLNGKDTDNQTTEEGATRKPRRRTKKTRLAEEEFPNELGVEDEDIIPDGHTKIPTQNPAFLASSLTSQPVGKLFVEKNRRFQAADRSEIIKTTEQMDVFLDVKPTWSSMDVSLTAHHIFRMVGLFCCGFLAGYAVWNIVVIYVLAGSQLTNLPNLLQTYKILAYPSQCFLYFLLVLSTVTAFDRIDLERAADALRGLLKLDPAAVASFFYFVALFLVLSQQMTSDRMNFYTPPTQNGSLWQTDTEGQILQPWIVINLVVAILVGLAWLFLSCRPDIDHSEEAMFIPEEEDYPDMEKGMKIQG",
    "output": "Component of the transition zone in primary cilia. Required for ciliogenesis (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MILLEVNNRIIEEILTLKFENAAAGNKPEAVEVTFADFDGVLYHVSNPNGDKAKVLISISLKFYKELQEHGTDEVLKKVYGNFLVAPESGYNVSLLYDLESLPSNKDSVIHQAGMLKRNCFASVFEKYFKFQEEGKDGEKRAVIHYRDDETMYVEAKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNANARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFAAR",
    "output": "Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) . The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility . In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKPDKEKPEKDKDISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF",
    "output": "Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1-like complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility . Component of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females . May stimulate ubiquitination of histone H2A 'Lys-119' by recruiting the complex to target sites . Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes (By similarity). May also regulate the ubiquitin-mediated proteasomal degradation of other proteins like FANK1 to regulate apoptosis . May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1 (By similarity). May bind to DNA . May play a role in the repression of tumor growth and metastasis in breast cancer by down-regulating SRRM3 ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKQVENNNNDHLVQSTDPEHPSNLIPELCRKFYNWGWVTGTGGGTSIRRDDHIFIAPSGVQKELMKPENIFVLQFPTPKYPPSERKYIRKPLDLKPSACTPLFLAAFERGAGCCIHTHSQWAVLVTLLVEREKGPGGYFEISNIEQIKGIPRGKGKGMLGFFDTLRIPIIENTAFEEDLTGSLEKAMEENPDTCAVLVRRHGIYVWGDNVAKAKTQCESLDYLFQLAVEMHKLGIPWVKE",
    "output": "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAHDLKVGLFQDTSAF",
    "output": "Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAPSLASGPADRIIVALDGMAPEQALRFAAQLDGLRWVKVGLELFVQAGPEVVAQLREQGLRVFLDLKFHDIPATMAGACRRAAALGAELITVHACAGSEALKAAQAAAVEGAQQAGLNPPTLLAVTVLTSWEEQRLQRELAIQQSIGERVPALAQLSATAGIGGCVCSPLEAAALRAQHPEPFALVTPGIRPKGSAVGDQARVMGPAEAIAAGASQLVIGRPITKADDPSAAFAACCTQLLGSID",
    "output": "Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAGESFPFTSSTLRALRLQREWLDWEDRRRAAAQQCRRHRDLPCPQAQLLRPRRSCRDPAVHNALFSGDLQQLQILFQDEDAANMIVETVSNQLAWSAEQGFWVLTPKTKQTAPLTIAVARGYTDCARHLILQGAELDARIGGRAALHEACAQAHPDCVRLLLTFGAKANVSSEEGMTPLHLCTSPESLQCAKLLLEAGASVNVASQESEVTPLHVAAARGLEQHVALYLQNGADVALRTSQGETALNAACAGAEGPGSSRQHEAAARQLLEAGADPQAAGRKRHTPLHNACANGCGGLAELLLRHGASPGVTNGAGHTPMDCALQAVQDAPNWEPEVLFAALLDYGAQPVHPEMLKHCANFPRALEVLLNAYPCVPSCDPWVEAVLPELWQEHEAFYSSALSMENQPRQLQHLARLAVRAQLGSHCRQAAAQLPLPPLLRDYLLLGVEGRIQ",
    "output": "May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNISIISIGKLKEKYLKQGIAEYLKRLSSYAKVEVIELPDEKAPENLSEAEMLIVKEKEGVRILDKISDDTHVIALAIEGKQKSSEQFAESLDCLATYGKSKIAFVIGGSLGLSTEVMKRSNESLSFSKMTLPHQLMRLVLLEQIYRAFRINRGEPYHK",
    "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGQANYDGYQFIVIDTGGIHGDEEGIDEEMAKQSLLAVDEADVVLFMVDARDGVTVGDQAIADHLRKQNKKVYLVCNKIDGIDAHSAMADFYSLSLGELYGIAAAHGRGVEQLLEICFKPIAEEYPDVIVPKDVASEELEHDEIDYDKLPLKLAIVGRPNVGKSTLINRILGEERVVVYDMPGTTRDSVYIPMQRNEREYVLIDTAGVRRRGRIGEAIEKFSVVKTLQAIEDANVVLIVVDARETISDQDLNLIGFALNAGRSIVIAVNKWDGLQNDHKEEIKRELDRRLGFVDFARLHFISALHGTGVGHLFESVEEAYASATQRISTSKLTKIMEMAQEEHQPPLVSGRRVKLKYAHAGGYNPPRIIIHGNQVKDLPGAYQRYLINYFRKSLGVMGTPIKVEFREPVNPYEGKKNQLTLSQQRKRRRLMKFLKKKK",
    "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIPANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLRRQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVAFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR",
    "output": "Specifically methylates the adenine in position 1618 of 23S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MWIKELQLRNFRNYGTVDTEFSPGLNVFIGNNAQGKTNFLEAIYFLALTRSHRTRTDKELIQFSKNNLQLIGKLNRISGALSLELQLSDKGRITKINALKQARLSDYIGTMMVVLFAPEDLQLIKGAPSLRRKFIDIDLGQIKPIYLSDLSNYNYVLKQRNTYLKTISTINSDFLSVLDEQLADYGSKVIKHRIDFIGELTREANKHHEAISNGLESLIITYESSVTQQDHQTIKEAFLLNLQKNRQRDIFKKNTSIGPHRDDIHFFINDMNANFASQGQHRSLILSLKMAEVSLMKEMTGDNPILLLDDVMSELDNTRQIKLLETVINENVQTFITTTSLDHLLHLPDKIKTFHVNQGTLKAD",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIPSVLLVTLLLLSWTSAEKDLKVRVARSTNDETNLHWVKCGGSVPDGAVSIQNTYVSPARTEYVCKSNCEAGYYSTKDSKCHYPFGRVEQTTSVCEILVNRDNFELLEWKEGYAGSLPANAVSTCKTNRIYVGKGAYGLGKIEPAHHCLYYGWNGAETWTKTYQALTVNKDVIEQTMKDVKYQTEGVTVIQGKPEVMRKSTVNNKQCKEVTKTVTLSKDISTEERWDVTNSVTFGVTTTVTAGIPDVASASLAVSMEARRDFAHGASKTESQSYMVTVSVPVPPKQSCTVSMVAQVNKADVPFTATLIRTYRGGKKTQTTTKGVYRTTQVAETHADVEQCTIIGDEKDCPKASK",
    "output": "Shows nociceptive, edema-inducing and kininogenase activity with release of kallidin from low molecular weight kininogen. The cleavage occurs at Met-Lys bonds."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSETAPAAPAAPAPAEKTPVKKKARKAAGGAKRKTSGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKRAGAAKAKKPAGAAKKPKKAAGTATAKKSTKKTPKKAKKPAAAAGAKKAKSPKKAKATKAKKAPKSPAKAKTVKPKAAKPKTSKPKAAKPKKTAAKKK",
    "output": "Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPASAQAPAQTPAPALPGPALPGPFPGGRVVRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEVAVDMEFAKNMYELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPNPIHLTVDTSLQNGRMSIKAYVSTLMGVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMKTCFSPNRVIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVNL",
    "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis . The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation . The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression .; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTAIVLNALNALGVTAEASGRNDLVVKTPEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLQAKGIASVRGRVANLVELLPGITHEHICDAITEAFFSHYGERVEAEIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFTHLLDERFIWGGVELHFDVEKGHITRTQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECDALLVDFPEQEKELRELSAWIARAVR",
    "output": "Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLTLAHYLVLGAILFAIAIVGIFLNRRNIIIILMAIELMLLAVNTNFVAFSHYLGDVHGQIFVFFVLTVAAAEAAIGLAILVTLFRKLDTINVEDLDQLKG",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLVLTRRVGEKIVIGEDIVITVLKIEGNSVKIGIEAPRHVKILREELYEELKSENIKASEVSKDDLKGVLKNDKGYKGPGTSS",
    "output": "A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEVREIPLPAATKLAADYITGAFPAESGFAYAQADDEAFCRRLAYLQGRTYDREGLADYLRAYHRRFSASVATMANIEKLRNERSVVIVGGQQAGLLTGPLYTIYKIITIIQLAKEQERKLGVPVVPLFWIAGEDHDIAEIDHVYVVEEGEVKKAAYPHKTNEKRMAADVLLDRMAAKEWIERVVKTYGETDVTNELLFFLSSCLDEARTFVDFFAAIVLRLFADHGLVVLNAGDAAVRPLERRFFAALIERHRDVTAAVLAQQEALRTLGYAPLIEIGRDAANLFYYDGRERSLLQYDEERGLFHNKAGTLVWTREELLELAETNPARLSNNVVTRPLMQEHLLPTLAFVAGPGEIAYWAELKEAFPLFDLEMPPVVPRLQATIVSRSLQTDLSDIGLEVADVLTGRLDEAKREWREATAQAPLASAFAKAKADIDAAHRPLRELGVAIDRGLEGLVAKNAAILQAQIEFLQHALERALLRKHETEWRKFWRIETSLRPNGALQERVWNVFYYINRYGFDFVEKLLAIRSPGNGMHKIVYM",
    "output": "Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKSTAESKETPSQDESTTSVPCTEAPLVEEGEEASFGAYKRIFTFAGRTELILQAVAILAACASGAGIALQNLIFGQFVTVITDFTNGISTPADFRDNAAELALYFVYLGIARLVLSYTYNTLLTYAAYRIVRNIRHAYLKAALSQEVAYYDFGSGGSIAAQATSNGKLIQAGASDKIGLLFQGLAAFVTLSLSRLWCKWKLTLICICIPVATIGTTGVVAAVEAGHETRILQIHAQANSFAEGILAGVKAVHAFGMRDSLVRKFDEYLVEAHKVGKKISPLLGLLFSAEYTIIYLGYGLAFWQGIHMFGRGEIGTAGDIFTVLLSVVIASINLTLLAPYSIEFSRAASAAAQLFRLIDRESEINPYGKEGLEPERVLGDVELENVTFSYPTRPGITVLDNFSLKVPAGKVTALVGQSGSGKSTIVGLLERWYNPTSGAIRLDGNLISELNVGWLRRNVRLVQQEPVLFQGSVFDNIRYGLVGTPWENASREEQMERVQEAAKLAYAHEFISELTDGYDTLIGERGGLLSGGQKQRVAIARSVVSQPKVLLLDEATSALDPHAETIVQKALDKAAEGRTTIVIAHKLATIRKADNIVVMSKGHIVEQGTHESLIAKDGVYAGLVKIQNLAVNASAHDNVNEEGEGEDVALLEVTETAVTRYPTSIRGRMNSIKDRDDYENHKHMDMLAALAYLVRECPELKWAYLVVLLGCLGGCAMYPGQAILMSRVVEVFTLSGDAMLDKGDFYASMLIVLAAGCLICYLAVGYATNTIAQHLSHWFRRLILHDMLRQDIQFFDREENTTGALVSRIDSYPHAILELMGYNIALVVIAVLQVVTCGILAIAFSWKLGLVVVFGGIPPLVGAGMVRIRVDSRLDRQTSKKYGTSSSIASEAVNAIRTVSSLAIEETVLRRYTEELDHAVSSSVKPMAATMICFGLTQCIEYWFQALGFWYGCRLVSLGETSMYSFFVAFLSVFFAGQASAQLFQWSTSITKGINATNYIAWLHQLQPTVRETPENHDKGPGSGAPIAMDNVRFSYPLRPDAPILKGVNLKINKGQFIAFVGSSGCGKSTMIAMLERFYDPTTGSITIDASTLTDINPISYRNIVALVQQEPTLFQGTIRDNISLGVFNPNTQPFFSDKDAVKSVSDEQIESALRAANAWDFVSSLPQGIYTPAGSGGSQLSGGQRQRIAIARALIRDPKILLLDEATSALDTESEKIVQKALEGAARDGDRLTVAVAHRLSTIKDANVICVFFGGKIAEMGTHQELIVRGGLYRRMCEAQALD",
    "output": "Pleiotropic ABC efflux transporter involved in the protection of the cells against a wide range of toxic compounds."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNSDDDSVFNDDLNDSEITNLIHNIPSSSSSCSSSKNKLQRNLYGEIIPEQYVEIDSSKGYTELPPTHHALNYENLSSYIYPTNFEVRDYQFNIVQRAFYDNLLVALPTGLGKTFIASTVMLNFTRWFPRGKIIFMAPTKPLVAQQIKACCGITGIPTSEVAILLDKSRRNRADIWDSKTVFFTTPQVVENDLTAGIIDPKEVVLLVIDEAHKSKGNYAYNNVVKFITRFNISFRILALTATPASDVEGVQEIIDNLSISKVEVRTEQSIDITKYMKQKKIERVTVSPSVEICELVDMLCTAIQPVLSMANERRIYDMSDPSKINAFQVIDASQRLLKNPTIPEGLKWQNYFILQILNVVGQALRRLNIYGIKSFYNYFDQKHKEFTIKFKNKKSNNQTAARFYFHDNIKLILDKCKELIADDNFLGHPKLEILINELDEFFKENEANDSRVIIFTEFRESALDIVSSIERIGSNLRPHIFIGQSKEKEKFDEEAYLSKGKKGRTKGKATKGKQNSETPERSTSRTSSEDAQIKGMNQKLQKDLIKKFKKGEYNILVATSIGEEGLDIGEVDLIVCYDSTSSPIKNIQRMGRTGRKRDGKVLLLFAGNEESKFDKAMAGYEFIQQHIMNGRLITLAQSNRIIPKSYKPIVEKKFIEIPEENTEIKAEEDEDEIIRIATSYMNNKGKKVTKSKSKSKSNSKSKKIEKRFFMPDNVTTGFQNVTSMVRKADSDKSVADKRREKDLLDKLLDSDTEDELLIQSKKSPVKENQSKRPNSEHICEEDSRQETENNSNESNGSFENENDQNKESGVSYPLSYRQTPPKLGIRRLSPQVSMNINLDAPVATEEAAPLVTGKSTSPPENVAEKRNSPILNSSNRECAPKQKTLGLKRRKANSITDQLKRHYSRVIKPNTAYRTITVSDDEKSVEDSINNQQLHKNKNLGSTSDDDDAFDEGDVFDDGMDDELALIANDKLSSFERSLSPNLPAQNNASDEVYKHEFSPGEGVLNQEQMLELYTSYFSLLDPADRVDFYDPLNFNQKPNTSINHRGRIGHSQVSRRLLQSSKFIGSVSTTTAKNIVKRYAQTYNTTNHQHNMHIVQEITNSSSK",
    "output": "ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNTDDVLAVFREAGAILEGHFILTSGLRSPVFLQKARVFMHADKTEKLCKALAEKIRAADLGPIDYVVGPAIGGLIPSYETSRHLGVPSVWVERENGVFRLRRFDVPKGARVVIVEDIVTTGLSIRETIDCMKDLGIEVVAAACIVDRSAGKADVGTRLISLAAYEVPAYPADKLPPELAAIPAVKPGSRNI",
    "output": "Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFLGDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIVYPKINEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSGKSKKEAEQQAAAEALKKLKEQL",
    "output": "Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLTLYGETFPSRLLLGTAAYPTPEILKQSVRTARPAMITVSLRRTGCGGEAHGQGFWSLLQETGVPVLPNTAGCQSVQEAVTTAQMAREVFETDWIKLELIGDDDTLQPDVFQLVEAAEILIKDGFKVLPYCTEDLIACRRLLDAGCQALMPWAAPIGTGLGAVHAYALKILRERLPDTPLIIDAGLGLPSQAAQVMEWGFDGVLLNTAVSRSGDPVNMARAFALAVESGRLAFEAGPVEARTKAQASTPTVGQPFWHSAEY",
    "output": "Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGVIHEETAYRKPVPGGDPGAGSGAADHRDSAGRLSRWEATGDVRNVAGTDQGRSVASGASRVGRVRGQELARGVRAGNGGSAGTSGVHRPEVGSGRQEKTGNQTMKTLVTANQKGGVGKTSTLVHLAFDFFERGLRVAVIDLDPQGNASYTLKDFATGLHASKLFGAVPAGGWTETAPAAGDGQAARLALIESNPVLANAERLSLDDARELFGANIKALANQGFDVCLIDTAPTLGVGLAAALFAADYVLSPIELEAYSIQGIKKMVTTIANVRQKNAKLQFLGMVPSKVDARNPRHARHQAELLAAYPKMMIPATVGLRSSIADALASGVPVWKIKKTAARKASKEVRALADYVFTKMEISQ",
    "output": "This is one of the proteins encoded by the trfB operon; it is involved in plasmid maintenance and replication."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPSARGKSKSKAPITFGDLAIYFSQEEWEWLSPIQKDLYEDVMLENYRNLVSLGLSFRRPNVITLLEKGKAPWMVEPVRRRRAPDSGSKCETKKLPPNQCNKSGQSICQKLVSAQQKAPTRKSGCNKNSVLVKPKKGHSGKKPLKCNDCGKTFSRSFSLKLHQNIHTGEKPFECSNCRKAFRQISSILLHQRIHSGKKSHECNKCGESFNQRTTLILHMRIHDGKEILDCGKALSQCQSFNIHQKIHVVGNVCQCRKCGKAFNQMSSLLLHKKIHNGKKTHKYNKCGRGFKKKSVFVVHKRIHAGEKIPENAKALSQSLQQRSHHLENPFKCRKCGKLFNRISPLMLHQRIHTSEKPYKCDKCDKFFRRLSTLILHLRIHNGEKLYRCNKCEKVCNRHSSLIQHQKVHTKKKKLFECKECGKMFSGTANLKIHQNIHSEEKPFKCNKCSKVFGRQSFLIEHQRIHTGEKPYQCEECGKAFSHRISLTRHKRIHTEDRPYECDQCGKAFSQSAHLAQHERIHTGEKPYTCKTCGKAFSQRTSLILHERSHTGEKPYECNECGKAFSSGSDLIRHQRSHSSEKPYECSKCGKAYSRSSSLIRHQNTHSEEKA",
    "output": "May be involved in transcriptional regulation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNPSEVASAGIHPIELCVHSILSSNLEGIYQAITELRESQALLVMKFNQVKKSFMDEQELLQEEGSLKEELARVNQLKKRLDKLTELYAELARKCGAL",
    "output": "Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MADAAMSGEEKEEDGGKRTTAATPAETLGFYEPSDGSRVETKKRSLSDLSLLRFISAELTRGYFLENNEAKYKERREKVYTCLRIPRELEKLMVFGFFLCLDAFLYVFTLLPLRVLLALIRFLTLPCCGLSDGRVLQPAQVCDVLKGVILVICYFIMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHLGVIPHFFMAVLYVILHAILILVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFSWNPDHLWVLFPDVCMVIASEIAVDVVKHAFITKFNDITADVYSEYRASLAFELVSSRQKNACTDYSDSVSRRMGFIPLPLAVLLIRVVTSSVKVQGILAYSCVVLFYFGLITLKVLNSIVLLGKSCQYIKDANMEEKLFQPPTCQPGKTPKKAQNKSKPNQGHPPDETANTSVTSQPTKAASTAQLLVESNSDKLLTTPDAEEKDISGDNSELKQKQADKDLLDIDRFTICGNRID",
    "output": "Plays a role in primary cilia formation. Involved in cartilage and bone development. May play a role in the differentiation of cranial neural crest cells. May act as a downstream effector of hoxc8 during development."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKRFWAMVCALFLSVSLLLTSCANVPTGLTGNFREDTLALISSLREAIALPENDPNKKAAQAEARKKLNDFFALYRRDDSLRSLSSFMTMQTALNSLAGHYSSYPNRPLPEKLKARLEQEFKQVELALDREAKS",
    "output": "Plays a role in the repair and/or biogenesis of the calcium-manganese-oxide cluster on the lumenal face of the thylakoid membrane. Its presence in a photosystem II (PSII) preparation prevents binding of other extrinsic subunits PsbO, PsbU and PsbV, and thus assembly of calcium-manganese-oxide cluster. Psb27-containing complexes lack oxygen evolving activity and an oxidizable calcium-manganese-oxide cluster, but have a normal reaction center."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDRGAAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLVQGQKLYFAHHPAFAHFETIDLSQATVAESSCRNLCHSFCVITPQRKITLAAPNRKDMEEWINIIKTIQQGEIYKIPAAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSDFWNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRETPRQTPLLKGQVEMDVPRFEAAAIQHLESAATELNKILKAKYPTEMIIATRFLCSAVEDFVVDIVKAWGQIKQNNTAIVSVILKSDLMYDRLSVLIDVLAEEAAATSAEKSATEYADSSKADRKPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQVEQALDEESRQTISVKNFSSTFFLEDDPEDINQTSPRRRSRRGTLSSISSLKSEDLDNLNLDHLHFTPESIRFKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQMLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEEYAQMQHLARLAENLISKLNDLSKIHQHVSVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETLSRNDAVDVTFSLKGLYDDTTAFLDEKLLRSAEDETALQSALDAMNKEFKKLSEIDWMNPIFVPEEKSSDTDSRSLRLKIKFPKLGKKKVEEERKPKSGQSVQSFIGNLWHRRHREDEAEGDDPLTPSRSQL",
    "output": "Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids . Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKFAVSSKGDQVSDTLKSKIQAYLLDFDMELDENEPEIVISVGGDGTLLYAFHRYSDRLDKTAFVGVHTGHLGFYADWVPHEIEKLVLAIAKTPYHTVEYPLLEVIVTYHENEREERYLALNECTIKSIEGSLVADVEIKGQLFETFRGDGLCLSTPSGSTAYNKALGGAIIHPSIRAIQLAEMASINNRVFRTVGSPLLLPSHHDCMIKPRNEVDFQVTIDHLTLLHKDVKSIRCQVASEKVRFARFRPFPFWKRVQDSFIGKGE",
    "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. It can use ATP and other nucleoside triphosphates (GTP, UTP) as well as inorganic polyphosphate (poly(P)) as a source of phosphorus."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIEITLLGTGSPIPDPDRAGPSTLVRAGGQVFLVDCGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAADPAPLQVIGPPGTAETVDAMLKAFGRDIGYRIAHHADLNAPPPIEVHEYTDGTVWDRDGVAIRVAPTDHRPVAPTIGFRVEFDGASAVLAGDTVPCPSLDELAAGAGALVHTVIRKDIITNFPQQRVKDICDYHSSVQEAAATAARAGVGTLVMTHYVPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR",
    "output": "Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSQAYSSSQRVSSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGTTRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTYSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL",
    "output": "Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity . In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures . May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction. Contributes to the transcriptional regulation of the NKX2-5 gene in cardiac progenitor cells during a short period of cardiomyogenesis and in cardiac side population stem cells in the adult. Plays a role in maintaining an optimal conformation of nebulette (NEB) on heart muscle sarcomeres to bind and recruit cardiac alpha-actin (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKRSLDPSDDFKGQKRLAIDPESTALEQDRQMLQQLSEQNSELEPQNVAPNAEIPLGFDLSGIQFNMTPDFYLRMNQGMDYAFNQPNPIATPQQLLRTSLIPTLGNLSNIILSILGKPVQEASAIVTNPASEMGMAFTKVMNMFRMVKDIYTEESFIYSSAIGMRTPSQRSTTRRANLAIFLAAVYGALQIGFFHLNENFLEVFAPDESNILTNQGTLYMELKTQAYISAMAQAERPKGDILNDLFPSDMAHRFLIRRNAKLDDKLTYVEKQIIEKCTARKERLANFSPQEALNEVYPWGKFLSEIACYIHNNYSSISAIPIPANSFKRRSKKNGLRFKAGEAESSPSESGSDLTDSLAFGIPSSTFDGSSETQNVSSVVLYDQVRHMTNNNLNNKRTRRVANRRSWTKEEEEALLDGLDLVKGPRWSQILELYGPGGKKSEVLKYRNQVQLKDKARNMKLFFLKSGQVVPAALQCVTGDLRRD",
    "output": "Binds the telomeric double-stranded TTACAGG repeat and regulates telomere length."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKVLFLTIALSLFSILQAQDSSSSEEQFEGTYFVKAIVTDSEFFEKNKPKALSPLTVTHLSNGDLEAKFTTNMNGICEEIKMKFEKTDKPGIFSTNDGSRQVLIEKTSVRDHWILFCEGELHGMQVRIAKLLGPHTDENPKAFQEFKKFVSLKRFNEEKINIPRQTETCIPEHV",
    "output": "Probably serves a role in the transport of a small ligand released during the hydrolysis of milk fat."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "SGLQFAVLDGQGFLPFSRV",
    "output": "Mediates visceral muscle contractile activity (myotropic activity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVAINSITLPFVENESRAKAVKEQIDAIFQQTGTRPLVFYSIVIPEIRDIILQSEGFCQDIVQALVAPLQGELKLDPTPIAHRTHGLNPGNLIKYDARIAAIDYTLAHDDGISMRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPPALKPLQHKLFGLTINPERLAAIREERRENSRYASMRQCRMEVSEVEALYRKNQIPWLNSTNYSVEEIATKILDIMGLNRRMY",
    "output": "Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAVIKMKPTSPGQRGAVKISRDHLFKGAPHAPLLEPQFQKAGRNNNGHITIRHRGGGAKHHYRVVDFVRNKDGIPAKVERIEYDPNRTAHIALVCYADGERRYIIAPRGLEAGATLLSGSEAPIRAGNTLPIRNIPVGSTIHCIELQPGKGAQIARSAGTSATLLAREGVYAQVRMRSGEVRRIHIECRATIGEVANEEHSLRQLGKAGVKRHMGIRPTVRGVVMNPVDHPHGGGEGKTGEGRHPVDPWGNLTKGYRTRNNKRTQVFIVSRRKK",
    "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MQKIKSLMTRQGLKSPQESLSDLGAIESLRVPGKEEFRELREQPSDPQAEQELINSIEQVYFSVDSFDIVKYELEKLPPVLNLQELEAYRDKLKQQQAAVSKKVADLILEKQPAYVKELERVTSLQTGLQLAAVICTNGRRHLNIAKEGFTQASLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNTDTKFQKLQYKDLCTHVTPDSYIPCLADLCKALWEVMLSYYRTMEWHEKHDNEDTASASEGSNMIGTEETNFDRGYIKKKLEHGLTRIWQDVQLKVKTYLLGTDLSIFKYDDFIFVLDIISRLMQVGEEFCGSKSEVLQESIRKQSVNYFKNYHRTRLDELRMFLENETWELCPVKSNFSILQLHEFKFMEQSRSPSVSPSKQPVSTSSKTVTLFEQYCSGGNPFEIQANHKDEETEDVLASNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDGPVKSVSRETLKSRKKSDYSLNKVNAPILTNTTLNVIRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAIYTFFGRNDSLESTGLGLSSSRLRTTLNRIQESLIDLEVSADPTATLTAAEERKEKVPSPHLSHLVVLTSGDTLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAVKKPFLQQFYSQTVSTASELRKPIYWIVAGKALDYEQMLLLMANVKWDVKEIMSQHNIYVDALLKEFEQFNRRLNEVSKRVRIPLPVSNILWEHCIRLANRTIVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDKEFVETYIKAYYLTENDMERWIKEHREYSTKQLTNLVNVCLGSHINKKARQKLLAAIDDIDRPKR",
    "output": "Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSDSLRIIFAGTPDFAARHLDALLTSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQHLVADLHADVMVVVAYGLILPKAVLDMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLACPITAEDTSGSLYNKLAELGPQGLITTLKQLADGTATPEAQNEALVTHAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIDGQPVKVWQASVIEDATQSLPGTILAATKQGIQVATGKGILNLLSLQPAGKKAMSAQDLLNSRREWFIPGNRLA",
    "output": "Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARHKNVPFESGIDSVGTARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLARIGALDWTPARSRRERMNPETNSIANRQR",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "HEPCGESCVFIPCITTVVGCSCKNKVCYD",
    "output": "Probably participates in a plant defense mechanism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAVEKTNSSSSLAEVIDRILDKGIVIDAWARVSLVGIELLAIEARVVIASVETYLKYAEAVGLTQXAXXAX",
    "output": "Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDVRRRSEEAVYSSKVFAADEKPLKPHKQQQEEDNTLLIDASDALPLPLYFTNGLFFTMFFSVMYFLLSRWREKIRNSTPLHVVTLSELGAIVSLIASVIYLLGFFGIGFVQTFVARGNNDSWDEEDENDEQFILEEDSRRGPCAAATTLGCAVPTPPAKHIAPIVPQQPAVSIAEKPAPLVTPAASEEDEEIIKSVVQGKIPSYSLESKLGDCKRAASIRKEVLQRITGKSLEGLPLDGFNYESILGQCCEMTIGYVQIPVGIAGPLLLNGREYSVPMATTEGCLVASTNRGCKAIYASGGATSILLRDGMTRAPCVRFGTAKRAAELKFFVEDPINFETLANVFNQSSRFARLQRIQCAIAGKNLHMRFVCSTGDAMGMNMVSKGVQNVLDYLQNEYADMDVIGISANFCSDKKPAAVNWIEGRGKSVVCEAIITEEVVKKVLKTEVAALVELNMLKNLTGSALAGALGGFNAHASNIVSAVYIATGQDPAQNIESSHCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQSACLNLLGVKGANREAPGSNARLLATIVAGSVLAGELSLMSAISAGQLVNSHMKYNRSTKDVTKASS",
    "output": "Catalyzes the synthesis of mevalonate. The specific precursor of all isoprenoid compounds present in plants."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAEVEHQDTVNHRVLVSLKEAARIIGAQGMTIQKIRESSKVKIGISPHERGCSDRILSCSGSAQGVANAIGDVVEVLNQDDSEPETHSYKPLNFILPAPSATEIQDPESVKRIGNLRLIVSNSQVSSIIGTQGSRIKSLIEKHGVKVVASKNFLPDSQDRVVEIQGFPGAIASCLVDISEILAAEPKPSHEKQYYPHTKSQEEGSVTKDVAIPVEYVGALLGRGGNRVSSLRKYTKTKVIVSDEPDEENNRVFTITGNNQNSVKLAETMLLKNLETEKQRREDKV",
    "output": "RNA-binding protein involved in the correct localization of transcripts in the cell. RNA localization is a widespread mechanism for achieving localized protein synthesis. Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MARNIKMATDAQNWLQARGSHVNESYLGVARPILEITYPPVELVKNAVRIMEHKSGVARSVWTARLNGCQIIWR",
    "output": "Expression of the kil gene induces dramatic morphological changes in the host cell, which becomes enlarged and predominantly spherical and possibly dies. These changes might involved a direct or indirect interaction with host actin-like protein MreB."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MADRPLTQQRLRKSFGKIAKIVDIPNLIEMQRISYQRFLQMDVPPEKRETIGLQAVFHSVFPIRDFSGTASLEFVSYRFGEIKYSVEDCVHRGMTYEVPIRITVRLVVFDVDKEKGIQNIRDIKEQEIYFGTIPLMTEQGTFVINGTERVVVSQLHRSSGVFFDHDKGKSHASGKVIYTARIIPVRGSWIDMEIDPKDVLYIRIDRRRKFPATLLFKAFGYSTEDLLNYFYQTEKLTLTPKTLFKEFDAKTLRGQRASITVKMPDSDEVIVKKGRLFTQRAVKTMAQAGIEKVAILQEDLEDKVLARRVLDPKTGEVLYPANHEIDEATLEAMRDAGVQKFEILYSAPGTGGDSVRKALLLDKVESREEALVEIYRRLRPSNPSTVEVAKDFIDQLFFRPSHYDLSAVGRMKLNMRLGLDTPVEVKTLRREDILLTAKTLVDLKDSQGAVDDIDHLGNRRVRAVGELLENQYRIGLVRMERAIKERMSLQEIDALMPNDLINPKPVSAVVKEFFGTSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPSHYGRICPIETPEGPNIGLIVSLSTYARVNEFGFVETPYRVVTEGQATKEIKYLSAMEEKDLPIAQANAPLDEEGFFINPTVSSRVEGELTIVKKEDVKLMDISPNQLVSVSSSMIPFLENDDANRALMGSNMQRQAVPLLATEAPLIGTGLERVVARDSGVTLVAKRDGKVVAVDASRIVLQHEDERKDRMDKQVTIYNLSKFTRSNQNTCFNQRPIVKLGQEVKAGDIIADGPATENGELALGRNVTVAFLPWGGYNFEDSILVSERLVRDGVFTSVHIEEFEVVSRDTKLGKEEITRDIPNVGEEALKNLDDSGIVRLGAEVRPGDILVGKITPKGETQLSPEEKLLRAIFGEKAGDVKDTSLRVPPGVEGVVVDAKVFARRGVEKDDRTRLIEDEEIAALEKDRDDELKIMEDTVRSKLITIVLGQEATAPVKKGKAVLIPKGQPITAEMLEDCPLAPLEALVLKDEDHSERVHELLEIYREQRESVQMSFEEQVNRYQKGDDLPPGVIKMVKIYVAMKRRLSVGDKMAGRHGNKGVVSCILPQEDLPYFENGTPVDMVLNPLGVPSRMNVGQILEIHLGRAAKSLGDQIEALLEEQKLDGLRQKMQEIFSSDADEVAGLTEQELLEVAGQYKRGVHMATPVFDGAKEDEITDLLSSAGVSPSGQAVLYDGRTGERFKGEITVGTMYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEFLTVKSDDMVGRTRMYEKIVKGQNVLEPGMPESFNVLVKELQSLGLEMSLIEEAK",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRLFIALPVLIVVVAMTLEGPAPAQAAPDLSGTLESIPDKLKEFGNTLEDKARAAIEHIKQKEILTKTRAWFSEAFGKVKEKLKTTFS",
    "output": "Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein (By similarity). Binds free fatty acids and reduces their intracellular esterification."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTNTPQSHPLIKIVNHSFIDLPAPSNISAWSNFGSLLGVCLGLQLLTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGILFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVTYFFIILILMPSTALMENKLLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MYSSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKAEVKQKWASRLLAKLRKDIRPECREDFVLAITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAEQSGSPRAGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHMAYDLNPASTGMRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSNRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMSSHCLSAQMLAPPPPGLPRLALPPATKPTSEGGSSSPTSPSYSTPGTSPANRSFVGLGPRDPTGIYQAQSWYLG",
    "output": "Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKAFSCLLAVIATAASLFQHVDASHARDKLNNISRVERPVIHTPSRRVHAHSHFDLTFDLYPRRNRIKLQLEPNHDVLSHNARVTFLDTEGNVDRIERIERRDHSVFKGWAWTQAKSGVWERVGWARIIMHRDGEDPLFEGVFTVMHDHHQVIAKSKYVRKRHQQDPPLDNTPGEYMLLFRGSDIAQTQSTGNVERSIMSSPSCDADTLAYDSNSNFMFPPLPEENNTSIWNYFMTSIGKRQMTDTGGVVPGSRDLKETIGSTSGCPNTRKVALIGVVADCTYTNTFASEMDARADIISVVNAASVVYEHSFNISLTLGEINILPKNCPATASSATPFNQQCDDRAGGGSFTLADRLNTFSAWRGKKTDDFAFWTLMTDCTTENQVGLAWAAQLCVKGVQGNPDSRNSSSQAVAGANVVSKTDNTWQVFAHEAGHIFGAVHDCDSMLCQNPANPDNSRCCPATASTCDARGRFMMNPTSGSQITNFSPCSIGQICSRMARRTILTNCLTTNRGVDTISGQQCGNGIVEDGEDCDCGDEESCKGNTCCDPKTCKYTSGSQCDDANEECCKGCKFASSSTICRTSSGPCDPEEKCSGNSGDCPHDIHSKDGGTCGTDLQCASGQCTSRDLQCQMHLGNQVAGSRTVAFDSYGCEVACKDPDRPNVRYEGSLTFLDGTPCGGGGTCKNGQCSGSTFGNEVSDWVSRHKPIVIGVAVGAGCLLLLAIASCICGRSRRQRPRNRKMPPINMRPMAPAYNGWNGAPPNAQQSSPGGHPPYNNIPPPINAPPPAYPGHMPPTRYA",
    "output": "Probable zinc protease."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAADKRDYYEVLGVHKNASDTEIKKAFRKLAIQYHPDKNPDDKEAEEKFKEITEAYEVLSDPQKRAQYDQFGHAGVGAGGFSGGGFGGFGAGTPFGDIFGDIFGDIFGGRPRGSRGRRGDDLQYNMELSFEEAAFGAEKEIQVPYGKRCGDCGGSGAKPGTEPKVCPTCRGAGQVRFQQGFFSVSKTCNHCNGEGRVVENPCTSCRGSGMIRDTKTLSVKVPAGVETGTRLKLSGEGGQGIKGGGNGDLYVAIAVREHPIFTREDNDVLCEIPVSFVQAALGCEIEVPTLDGKVSMKIPEGTQSGRIFRLRGKGVPQLQGYGRGDQLVIIKVETPSNLNKRQRELLEEFARISGEDVHPMKKSFFDKVMDFIS",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRHHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIEGQSKPLLIYGKPEAQQASGE",
    "output": "ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKTYVGSRVRQLRNERGFSQAALAQMLEISPSYLNQIEHDVRPLTVAVLLRITEVFGVDATFFASQDDTRLVAELREVTLDRDLDIAIDPHEVAEMVSAHPGLACAVVNLHRRYRITTAQLAAATEERFSDGSGRGSITMPHEEVRDYFYQRQNYLHALDTAAEDLTAQMRMHHGDLARELTRRLTEVHGVRINKRIDLGDTVLHRYDPATNTLEISSHLSPGQQVFKMAAELAYLEFGDLIDAMVTDGKFTSAESRTLARLGLANYFAAATVLPYRQFHDVAENFRYDVERLSAFYSVSYETIAHRLSTLQRPSMRGVPFTFVRVDRAGNMSKRQSATGFHFSSSGGTCPLWNVYETFANPGKILVQIAQMPDGRNYLWVARTVELRAARYGQPGKTFAIGLGCELRHAHRLVYSEGLDLSGDPNTAATPIGAGCRVCERDNCPQRAFPALGRALDLDEHRSTVSPYLVKQL",
    "output": "Involved in the control of the glyoxylate cycle. RamB negatively controls the expression of icl expression during growth on acetate as the sole carbon source. Does not regulate the expression of other genes involved in acetate metabolism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLIDPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQLQAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL",
    "output": "Transcriptional corepressor. Recruits NR2E1 to repress transcription. Promotes vascular smooth cell (VSMC) migration and orientation (By similarity). Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of poly-Gln (polyQ) repeats."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAYGVKIAKGDAYKRAAIKRRHIRIRKHISGTAERPRLVVTRSNRHIVAQVIDDVKGHTLASASTLDTTIRGGESDKSAQAKSVGALVAERAKAAGVEAVVFDRGGNQYAGRIAALADAAREAGLKF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKPSKHLIFALFALAISQPTMAAPQPIDRVAVQINDGIVLESEITNMIDTVKANARAANQSLPSDSALRTQVIERLILTRLQLQMADRIGLHIGDLQLDQAIENIAREQKMTVAQMQQKIESEGLSFGQYREQLREEITLGEIQRIQVQRRIQVSPQEITGLVKLIQEQGMKDVEYQIGHILIDVPNNPNSEQLEASSKRANAVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINEMPTLFAEVINGAKKGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILSEDRAKAMLEQFLKQIRSGEAKFEDLARQYSEDPGSATKGGELGWAEPSIYVPEFAQTLNSLSPDQISEPFRTTHGWHITQLEERRKTDATDQFNTNRAHQLIFRRKFNEELQNWLDEMRADAYIEVFQPESNRG",
    "output": "Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKRIPRKTKGKSSGKGNDSTERADDGSSQLRDKQNNKAGPATTEPGTSNREQYKARPGIASVQRATESAEMPMKNNDEGTPDKKGNTKGDLVNEHSEAKDEADEATKKQAKDTDKSKAQVTYSDTGINNANELSRSGNVDNEGGSNQKPMSTRIAEATSAIVSKHPARVGLPPTASSGHGYQCHVCSAVLFSPLDLDAHVASHGLHGNMTLTSSDIQRHITEFISSWQNHPIVQVSADVENKKTAQLLHADTPRLVTWDAGLCTSFKIVPIVPAQVPQDVLAYTFFTSSYAIQSPFPEAAVSRIVVHTRWASNVDFDRDSSVIMAPPTENNIHLFKQLLNTETLSVRGANPLMFRANVLHMLLEFVLDNLYLNRHTGFSQDHTPFTEGANLRSLPGPDAEKWYSIMYPTRMGTPNVSKICNFVASCVRNRVGRFDRAQMMNGAMSEWVDVFETSDALTVSIRGRWMARLARMNINPTEIEWALTECAQGYVTVTSPYAPIVNRLMPYRISNAERQISQIIRIMNIGNNATVIQPVLQDISVLLQRISPLQIDPTIISNTMSTVSESTTQTLSPASSILGKLRPSNSDFSSFRVALAGWLYNGVVTTVIDDSSYPKDGGSVTSLENLWDFFILALALPLTTDPCAPVKAFMTLANMMVGFETIPMDNQIYTQSRRASAFSTPHTWPRCFMNIQLISPIDAPILRQWAEIIHRYWPNPSQIRYGAPNVFGSANLFTPPEVLLLPIDHQPANVTTPTLDFTNELTNWRARVCELMKNLVDNQRYQPGWTQSLVSSMRGTLDKLKLIKSMTPMYLQQLAPVELAVIAPMLPFPPFQVPYVRLDRDRVPTMVGVTRQSRDTITQPALSLSTTNTTVGVPLALDARAITVALLSGKYPPDLVTNVWYADAIYPMYADTEVFSNLQRDMITCEAVQTLVTLVAQISETQYPVDRYLDWIPSLRASAATAATFAEWVNTSMKTAFDLSDMLLEPLLSGDPRMTQLAIQYQQYNGRTFNIIPEMPGSVIADCVQLTAEVFNHEYNLFGIARGDIIIGRVQSTHLWSPLAPPPDLVFDRDTPGVHIFGRDCRISFGMNGAAPMIRDETGLMVPFEGNWIFPLALWQMNTRYFNQQFDAWIKTGELRIRIEMGAYPYMLHYYDPRQYANAWNLTSAWLEEITPTSIPSVPFMVPISSDHDISSAPAVQYIISTEYNDRSLFCTNSSSPQTIAGPDKHIPVERYNILTNPDAPPTQIQLPEVVDLYNVVTRYAYETPPITAVVMGVP",
    "output": "Inner capsid (core) component. Displays NTPase, RNA 5'-triphosphatase (RTPase) and RNA helicase activities and probably participates in transcription of the viral genome. Helicase activity might be involved in unwinding or reannealing dsRNA during RNA synthesis. RTPase enzymatic activity represents the first step in RNA capping, which yields a 5'-diphosphorylated plus-strand RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTWDGLPTQPLLMLLMLLFAAGSGSALAGCPGCGAGMQTGCRGGCVEEEDAGSPADGCTEAGGCLRREGQPCGVYSPKCAPGLQCQPRENEEAPLRALLIGQGRCQRARGPSEETTKESKPQGGASRSRDTNHRDRQKNPRTSAAPIRPNPVQDSEMGPCRRHLDSVLQQLQTEVFRGGARGLYVPNCDLRGFYRKQQCRSSQGNRRGPCWCVDPMGQPLPVSPDGQGSTQCSARSSG",
    "output": "IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNFLIFIAVASSLALGALCKKEGYPYDGNNCRYICFRNQYCDDLCKKLKGESGYCYGWNQSCYCYGLPDTEKTKPDKRCHSKG",
    "output": "Binds voltage-independently at site-3 of voltage-gated sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDMASLISSLLVLFLIFQNSCYCFRSPLSVFKRYEESTRSLSNDCLGTTRPVMSPGSSDYTLDIRMPGVTPTESDTYLCKSYRLPVDDEAYVVDYRPHANMDTAHHMLLFGCNVPSSTDDYWDCSAGTCNDKSSIMYAWAKNAPPTKLPEGVGFQVGGKSGSRYFVLQVHYGDVKAFQDKHKDCTGVTVRITPEKQPLIAGIYLSMSLNTVVPPGQEVVNSDIACLYNRPTIHPFAYRVHTHQLGQVVSGFRVRHGKWTLIGRQSPQLPQAFYPVEHPLEISPGDIIATRCLFTGKGRMSATYIGGTAKDEMCNLYIMYYMDAAHATSYMTCVQTGNPKLFENIPEIANVPIPVSPDMMMMMMMGHGHHHTEAEAETNTALQQPKREEEEVLNQDVHLEEDTDWPGVNLKVGQVSGLALDPKNNLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQESTILVVDPNTSKVLKSTGQNLFFLPHGLTIDRDGNYWVTDVALHQVFKVGAEKETPLLVLGRAFQPGSDRKHFCQPTDVAVDPITGNFFVADGYCNSRIMQFSPNGMFIMQWGEETSSNLPRPGQFRIPHSLTMISDQGQLCVADRENGRIQCFHAKTGEFVKQIKHQEFGREVFAVSYAPGGVLYAVNGKPYYGDSTPVQGFMLNFSNGDILDTFIPARKNFEMPHDIAAGDDGTVYVGDAHANAVWKFSPSKAEHRSVKKAGIEVEEITETEIFETHMRSRPKTNESVGQQTQEKPSVVQESSAGVSFVLIITLLIIPVVVLIAIAIFIRWRKVRMYGGDIGHKSESSSGGILGKLRGKGSGGLNLGTFFATHKGYSRKGFDRLSTEGSDQEKDDDDDGSDSEEEYSAPPIPPVSSS",
    "output": "Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MADPSEQKEKVVKEKKEKVKKEKVVKEKVAKASSSGQKKKDVKKETGLGLSVKKDENFGEWYSEVCKQDMIEYYDISGCYILRPWSMAIWEIMQIFFDAEIKKMKVKNCYFPLFVSPGVLEKEKDHIEGFAPEVAWVTKSGKSDLEVPIAIRPTSETVMYPYYSKWIRGHRDLPLKLNQWCNVVRWEFSNPTPFIRSREFLWQEGHTAFATKAEADEEVLQILELYRRIYEEYLAVPVVKGMKSENEKFAGGLYTTSVEAFIPNTGRGVQGATSHCLGQNFAKMFEINFENEKAETEMVWQNSWAYSTRTIGVMIMTHGDDKGLVLPPKVASVQVVVIPVPYKDANTQGIYDACTATASALCEAGIRAEEDLRDNYSPGWKYSDWEMKGVPLRIEIGPRDLENDQVRTVRRDNGVKEDIPRGSLVEHVKELLEKIQQNMYEVAKQKREACVQEVKTWDEFIKALNEKKLILAPWCDEEEVERDVKARTKGETGAAKTLCSPFDQPELPEGTLCFASGKPAKKWTYWGRSY",
    "output": "Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFRGGTHRLRGQPGLSLPHGPRCYGSAPPELQEKTLVLVKPDAVQRRLVGNVIQRFERRGFKLVAMKLLQADQGLLDKHYQQLRQKPFYPALLAYMTSGPLVAMVWEGYNVVRSTRAMVGDTDSAVAAAGTIRGDFSMHVSRNVVHASDSVETAQREIGFWFQRNELVAWESGDRDYTWGP",
    "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Through the catalyzed exchange of gamma-phosphate between di- and triphosphonucleosides participates in regulation of intracellular nucleotide homeostasis. Binds to anionic phospholipids, predominantly to cardiolipin; the binding inhibits its phosphotransfer activity. Acts as mitochondria-specific NDK coupled to respiration. Promotes the redistribution of cardiolipin between the mitochondrial inner membrane and outer membrane which is implicated in pro-apoptotic signaling (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTATILMIAMTLSTILAILSFWLPQMTPDMEKLSPYECGFDPLGSMRLPFSMRFFLIAILFLLFDLEIALLLPFPWAAQLNTPSIVILWAALILTLLTLGLIYEWLQGGLEWAE",
    "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIVIDGSIGEGGGQILRTTLALAALLGKPVRIVNIRAKRPRPGLQRQHLTSVKAVAELASARVEGLELGSTTLVFIPRGLRSGRFYFNIGTAGSITLVLQALLPVTAFAPGPVEVEIVGGTDVPWSPPIDYVRFVLRKLLAMFGFEFEIIVKRRGHYPRGGGRVVLRVTQPPHVLKPVKLEERGKVLRVEGLSHAVRLPRHVAERQARSAEAVLRSKLPGVPISIDLEWYEPSRDPHLGPGSGVVVWAVAEHSVLGSDSLGAKGKPAEAVGREAAEKLLEDLATGTALDRHASDMLIPYAALACGESILGGARLTMHAWTNIEVVKMLVPGAEMEFIEGGKLNEKFKLRVKGICYKPSS",
    "output": "Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAGEFYDSARIFVQAGDGGDGAATFRREKYVPRGGPDGGDGGRGGHVYLVADPGLNTLLPFRERTRFIAERGGNGGRSRKHGRNGRDVFIRVPVGTVARTVIDGETYSVDLDAPGLRLLAARGGRGGLGNVHFATSSYQVPRIAELGEPGERREIELELKLLADVGLIGFPNAGKSTLLSVISAARPKIAPYPFTTLQPNLGVVEVGEYSFVVADIPGLIEGAHRGVGLGFSFLRHIERTRLLIHIIDAAGVDGRDPVNDFSAINEELRLYQPALAQRPQVVALNKADLPEAQANLKRLRAAIPVSEQDLFVISAATREGVDALLQRVAERLREMPAPHRAPRDETLTWPVPEVDERLYTIERTGDGWRVRGRRIERLISMTNFAQPDAIMRIQRVLEASGIGAALQEAGIQNGDVLYIEQAAFDWEDGAITYRMPGVS",
    "output": "An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNRSSFDLLSTVEYGGCSAKLDPAKLSELLHDIPLPVDSRIMVDVSTHDDAGVYRLNDDTALIVTTDFFPPVCSDPYTFGRIAAANALSDVYAMGGRPLLVLNLTMFPSEGIPVEVLADILRGGQQTIDESGAFTMGGHTIDDPIPKYGLAVTGIVHPEHLVTNAGVRAGQCLVLTKPLGIGVAMAAHRLGLIGSEVYEAAIGQMCLLNRAGAELMQKYGIRGATDITGFGLLGHAKGLAEASDVCLHIDSRSVPVLPECLSLLRDGCIPGAAFRNLRFVGDMLRADCPTEYKMLLADAQTSGGLLMAVDADRAEDLVADLHRTGLHPFAAIIGYATDAEDAAKLIVT",
    "output": "Synthesizes selenophosphate from selenide and ATP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTEYTPDEKLRLHQLRKLRRRWLKDQELSHREPVLPPQKMGPMEKFWNTFLENKSPWRKMVHGVYQKSIFVFTHILVPAWIIHYYMKYHVSEKPYGIVETKPRIFPGDTILETGEVIPPMKEFPDQHH",
    "output": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MALPPNFMPLFRASLIGLGLGCSALALAASAQDAPEAETQAQETQGQAAARAAAADLAAGQDDEPRILEAPAPDARRVYVNDPAHFAAVTQQFVIDGEAGRVIGMIDGGFLPNPVVADDGSFIAHASTVFSRIARGERTDYVEVFDPVTLLPTADIELPDAPRFLVGTYPWMTSLTPDGKTLLFYQFSPAPAVGVVDLEGKAFKRMLDVPDCYHIFPTAPDTFFMHCRDGSLAKVAFGTEGTPEITHTEVFHPEDEFLINHPAYSQKAGRLVWPTYTGKIHQIDLSSGDAKFLPAVEALTEAERADGWRPGGWQQVAYHRALDRIYLLVDQRDEWRHKTASRLLVVLDAKTGERLAKFEMGHEIDSINVSQDEKPLLYALSTGDKTLYIHDAESGEELRSVNQLGHGPQVITTADMG",
    "output": "Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDNVDSDQTKPIPAYYCCYLLRSTVNKRAGLYVGSTPNPPRRLPQHNGLSKGGAKKTATKNRPWEMVLLVEGFMSRTAALQFEWAWQHEDSRHMSKGEPGNTKRRQRPRRSLTANLEKLHSLLQSPCFSRWPLNIRIFASDVYQLWRVWCDRANGTIPEHIRTIPDGNCPHNSPEPETDHPRVGSIDGIQTDYSKIQDYLEKAVFLLDDPNELHCKVCEAQAKPEKELVIVCPQASCFGISHLLCLSARFLKSSNDPNQLVPRSGTCPACSKLVQWPLMMQELSFRTRGGKEVQVILRKKARSDKRKAAAARPAEIDANTASNEPLESTAQAFDRLNENVHQDVLDEDWAEELDCASEDDTNERLKTGSKDQQRVEIVIEDSDEDDLEFL",
    "output": "Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGASVDEDGAELDLNLTRSHSGDELESLSRGRRSLGSPTVAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPTFKKATVTLEDHLACKCETVVAARPVTRTPGSSQDLRAAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKKALKETLGA",
    "output": "Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVDVIEQYLAYIETLQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKALSQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHTVIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVGIEQTSHFGQIVLRKEIQ",
    "output": "Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV",
    "output": "An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHKLAHTSFGIVGMFVNTCMVAKYVIINWEMFSMKKVNNDTVFGILQLETLLGDINSIFSEIESEYKMSREEILILLTLWQKGSMTLKEMDRFVEVKPYKRTRTYNNLVELEWIYKERPVDDERTVIIHFNEKLQQEKVELLNFISDAIASRATAMQNSLNAIIAV",
    "output": "Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence. Also, modulates the expression of genes not previously implicated in pathogenesis (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAKEVVFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLEKSFGAPLITKDGVSVAKEIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKAVAAAVVELKALSQECADSKAIAQVGTISANSDESIGDIIATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGAVELDNPFVLLVDKKISNIRELLPILEGLAKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVIAEEIGLELEKATLEDLGTAKRVVITKDNTTIIDGNGAEEQIKARVGQIKQQIEETTSDYDREKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRVASKIANVDVANEDQKHGVVIALRAMEAPLRQIATNAGEEASVVANTVKNGSGNFGYNAGNDSYGDMLEMGILDPTKVTRSALQFAASVAGLMITTEAMVAELPKADAPDMGGMGGGMGGMGMM",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKNNNFRLSAAGKLAAALAIILAASAGAYAAEIVAANGANGPGVSTAATGAQVVDIVAPNGNGLSHNQYQDFNVNQPGAVLNNSREAGLSQLAGQLGANPNLGGREASVILNEVIGRNPSLLHGQQEIFGMAADYVLANPNGISCQSCGFINTSHSSLVVGNPLVENGVLQGYSTFGNRNTLSLNGTLNAGGVLDLIAPKIDSRGEVIVQDFKQSNGKVTSAAINAISGLNRVARDGTVQASQQMPTALDSYYLGSMQAGRINIINTAQGSGVKLAGSLNAGDELKVKAYDIRSESRVDDASSNKNGGDNYQNYRGGIYVNDRSSSQTLTRTELKGKNISLVADNHAHLTATDIRGEDITLQGGKLTLDGQQLKQTQGHTDDRWFYSWQYDVTREREQLQQAGSTVAASGSAKLISTQEDVKLLGANVSADRALSVKAARDVHLAGLVEKDKSSERGYQRNHTSSLRTGRWSNSDESESLKASELRSEGELTLKAGRNVSTQGAKVHAQRDLTIDADNQIQVGVQKTANAKAVRDDKTSWGGIGGGDNKNNSNRREISHASELTSGGTLRLNGQQGVTITGSKARGQKGGEVTATHGGLRIDNALSTTVDKIDARTGTAFNITSSSHKADNSYQSSTASELKSDTNLTLVSHKDADVIGSQVASGGELSVESKTGNINVKAAERQQNIDEQKTALTVNGYAKEAGDKQYRAGLRIEHTRDSEKTTRTENSASSLSGGSVKLKAEKDVTFSGSKLVADKGDASVSGNKVSFLAADDKTASNTEQTKIGGGFYYTGGIDKLGSGVEAGYENNKTQAQSSKAITSGSDVKGNLTINARDKLTQQGAQHSVGGAYQENAAGVDHLAAADTASTTTTKTDVGVNIGANVDYSAVTRPVERAVGKAAKLDATGVINDIGGIGAPNVGLDIGAQGGSSEKRSSSSQAVVSSVQAGSIDINAKGEVRDQGTQYQASKGAVNLTADSHRSEAAANRQDEQSRDTRGSAGVRVYTTTGSDLTVDAKGEGGTQRSNSSASQAVTGSIDAANGINVNVKKDAIYQGTALNGGRGKTAVNAGGDIRLDQASDKQSESRSGFNVKASAKGGFTADSKNFGAGFGGGTHNGESSSSTAQVGNISGQQGVELKAGRDLTLQGTDVKSQGDVSLSAGNKVALQAAESTQTRKESKLSGNIDLGAGSSDSKEKTGGNLSAGGAFDIAKVNESATERQGATIASDGKVTLSANGKGDDALHLQGAKVSGGSAALEAKNGGILLESAKNEQHKDNWSLGIKANAKGGQTFNKDAGGKVDPNTGKDTHTLGAGLKVGVEQQDKTTHANTGITAGDVTLNSGKDTRLAGARVDADSVQGKVGGDLHVESRKDVENGVKVDVDAGLSHSNDPGSSITSKLSKVGTPRYAGKVKEKLEAGVNKVADATTDKYNSVARRLDPQQDTTGAVSFSKAEGKVTLPATPAGEKPQGPLWDRGARTVGGAVKDSITGPAGRQGHLKVNADVVNNNAVGEQSAIAGKNGVALQVGGQTQLTGGEIRSQQGKVELGGSQVSQQDVNGQRYQGGGRVDAAATVGGLLGGAAKQSVAGNVPFASGHASTQQADAKAGVFSGK",
    "output": "Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQDPGISPSQSLCAESSRGLSAGSLSESAVGPVEACCLVILAAESKVAAEELCCLLGQVFQVVYTESTIDFLDRAIFDGASTPTHHLSLHSDDSSTKVDIKETYEVEASTFCFPESVDVGGASPHSKTISESELSASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRHRRALSTTSSSTTNGNRATGSSDDRSAPSEGDEWDRMISDISSDIEALGCSMDQDSA",
    "output": "Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLTTVILAAGKGTRMRSALPKVLHKVAGKTMVQHVIDNAKALGATTTNLVYGHGGELLQQQLANNNVNWVLQAEQLGTGHAVAQANSHVNDDDTVLILYGDVPLTKQSTLERLLAATPKHGLAVLTVNLANPNGYGRMLRVDGKLVGIVEQKDASPEQLLISEVNTGIMAVNGRLLKSWLGNLSNNNAQGEYYLTDIVAMAHSEGVEITSAQPDHPMEVEGANNRIQLAGLERAYQAWQAQELMLNGATLADPARIDVRGTVTTGEDVLIDINVIFEGKVTIGHNVEIGPNCVLKNCSIGDNVIIKANTLIEDATVAAKCTLGPYARLRPGAIMEEDSHVGNFVEMKKTRLGKGSKANHLSYLGDAEIGEKVNIGAGTITCNYDGVNKAKTIIGNNAFIGSNSSLVAPVNIGAMATIGAGSVITNTVADEQLAIARGKQRNLDGWKRPVKK",
    "output": "Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKFASIITLIFAALVLFAAFDAPAMVEAQKLCEKPSGTWSGVCGNSNACKNQCINLEGAKHGSCNYVFPAHKCICYVPC",
    "output": "Confers broad-spectrum resistance to pathogens. Has antifungal activity in vitro."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MYQRVLVKLSGEVMCGEGSRGFDQSNINYLVQQIAQIVDYGVNVGIVIGAGNIFRGEELSEIPHSLADQIGMLGTVINALYLKGSLQKVGIKCVVVSQVTSLPSIRPIHYDDINLYFDAGYVVIFAGGTSNPFFTTDTAAALRAVEMGANLLIKATKVDGIYDSDPKKNKSARKLDKISYYDAISRGLKVMDMEAFSICGRYKLPIVILNFFEDGSLLRAVRGEDVGSIIMPD",
    "output": "Catalyzes the reversible phosphorylation of UMP to UDP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPTFSREEIVHLGDLARIALTDEEITRLQGELNVIADSINKVQEVASDDVPPTANPVPLEAYLRPDVAETPLTQEEALAGGPKTEAGMFVAPRILGSEE",
    "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPTVGSLVYIMVELAIALLAILGNMLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGVIAVCWVLSFAIGLTPMLGWNNCHHWGEGENQSQGCGEGQVACLFEDVVPMNYMVYYNFFACVLVPLLLMLGVYLRIFLAARRQLKQMETQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPECPHAPLWLMYPAIILSHFNSVVNPFIYAYRIREFRHTFHKIIRSHILRRQEPFKAGGTSARALAAHGSDAEQVSLRLNGHPSGVCPNGSAPHPERRPNGYALGLVSRASARESPGDTGLPDVELLSHELHGASPESPGLEGPLAQDGAGVS",
    "output": "Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSDKFHILLLNGPNLNLLGTREPEKYGYTTLAEIVSQLEIQAQGMDVALSHLQSNAEHALIDSIHQARGNTDFILINPAAFTHTSVALRDALLGVQIPFIEIHLSNVHAREPFRHHSYLSDIAVGVICGLGADGYNFALQAAVNRLSKSN",
    "output": "Catalyzes a trans-dehydration via an enolate intermediate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTIGLVGRKVGMTRVFTEDGVSTPVTVIEVEANRVAQVKTVDNDGYSALQVTTGKRKASRVTKPAAGHFAKAGIEAGRGLWEFRLNENEGSDIEAGSEITVEVFNDTKLVDVTGTSKGKGFQGGIKRWNFTMQHATHGVSLSHRSNGSLGQCQTPGRVFKGKKMSGHMGAVRCTTQNLELVRVDAERNLLLIKGAVPGAINGNVIIKPAVKA",
    "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSTQPIKVLIVDDSALIRSLLTDIINSQTDMEVVGVAPDPLVAREKIKALNPDVLTLDVEMPRMDGLVFLEKLMRLRPMPVLMVSSLTEKSSFLTLRALELGAVDFVTKPKIDISRGMQEYAREITDKLRVAAKARVRQPPHVHLSVERKNTADAVLPMEHRTFSSTEKIIVIGASTGGTEALKSFLVAMPADSPGILITQHMPEAFTRTFAQRLNSLCRISVKEAEHGERILPGHAYVAPGNRHLLLARSGANYVVELSDGPPVSRHRPSVDVLFRSAANRAGRNAVGIIMTGMGDDGAAGMLEMREAGAYTFAQDEKSCVVFGMPKEAIARGGVDEVAPLGEMPRRLFGWLESQGNRAFRV",
    "output": "Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVYSVGLTGNIASGKSTVAEFFSELGINVIYADKIAKELTSKNTPCYQDIISHFGSSVVLNNGELDRKRIRDIIFSNSNERLWLESLLHPVIRKKIEEQLIVCTSPYCLIEIPLLFNKHHYPYLQKVLLVIAPLESQLDRIVKRDHCTKKQALAILATQPNLEQRLEAADDVLINESGLSELKAKVNKLHQKYLREAKIKQ",
    "output": "Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKNVVIIGTQWGDEGKGKVVDLITDKVASVVRFQGGHNAGHTLVINGKTTILHLIPSGILRNHVECLIGHGVVLSMSALLKEIAELEVADIDTTKRLKISPGCPLILPYHIELDNAREIKRGKAAIGTTGNGIGPAYEDKVARRGLRVSDLLDPNLFASKLKEVMEYHNFFLTHYYNANPVDYQTTLDEVLSQVEQTKHMIVDVTEQIHQHIANDENILFEGAQGALLDIDQGTYPFVTSSNTTSGAAVTGSGIGVTDIDYVLGIVKAYTTRVGGGPFPTELIYDVALDKGDEIGKVLGTVGHEFGATTGRQRRCGWLDMVTLKRSFNLNAVTGICLTKLDVMDTLETIKICTSYEIDGVETTIPPFSAEDYAKAKPIYIKIPGWKTSTIGTDSFDSLPVEAQSYIRKIEQLANLPVDILSTGPDRLQTLILKHPFE",
    "output": "Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRVGCCLLLKPLRQRLCTASISSRHIMRWCATSSSNINSTETAAKMPDDDVSGSLSAPSLLKYKIEPSTATMGAPRPPHDDDRAFCTLASFPPSHIRNVAVVAHVDHGKTTLSDAILRRTGVLSGSQVGTYTDRLLVERERGITIKAQTCSIFVVWDGEEFLLNLIDTPGHVDFQYEVSRSLSASDAALLLVDAAQGIEAQTMAHFHMALDRGLTILPVLTKMDAVLSDAPVDRALQDLEDSTGLLRREVLFTSAKEQLGIEALLHAIIERVPPPTGLLGLSDLQQLPPLLPGSAERVAMEEKMVPLRALLFDSWTSECGGGLRRPAPRGGEKVNSGNDNDRNLICLVRIIDGTLTAKTVVTFYQSQRRCEALEVGIIHPELRPTAALTAGMVGYVVFSQVRGEEFLVGETLYTLPTRKFARENIVPVPGFRRVQPVVFAGFYPDEGEYITQLREAVEKLRVNEPAVTMEPLDCPALGSGLQLGFLGMLHMQVFQERLLAEFGQRVLVTPPLVQYKYREAGSDEEEPLKPLTVHTWKWIHEGAACYLEPYVTATIITRREHFQAIDGEALRRFRGEQLDMRVLDDARVLVRYKMPLADLARGFFAVVKSLSHGYASLDYGDPVYEEADLVKVDVLVQKSRISALSVICLRSEAPSIGKRIVSSLKSNLTRTAVDIPLQAMVGSKIVARETVKAYRKDVTAKIHAGDISRKQKKWNDQKKGKERMARRTVGAVTLDQSILAAAMGAISL",
    "output": "Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSRILLRGIQCHACRQNVIRSFVSASGVTITPPAIGSVSPSKAHPPHLSGSFPTRHVKLFSSQAKDDPSLAADAVSENSAAQEGSYPQENSEQHVPWYLQEEVQEMALHPMRQQQELPPLPENPPPILKVLLEYISFDIGLDNLNLLDLRTLDPPPALGANLIMIFGTARSVKHLNVSADKFCRWLRTTYKLRPDADGLLGRNELKIKLRRKARRARLVKRAGSTLKQPDDGITTGWICVDVGIVEGGQLSKPEGVQKAGFVGFGTVIQGTRIVVQMMTEEKREEIDLESLWRQTLEKNSMDNPGLPKPQAEEPPQVVGFTHESSTVTAADFSHRVSQTPPIRANYEQLRSISTSLHRLRDKRGSATDFVPTDTTVATKSAKSISSQESLPSLFNYLSNLEPDKAIDELGQGMDDRTSTSFLQRFYEELARTAPQIASAQKLELMCTGILLQHSGYRKEDLFQAFKEHIVSNYPLPRALVLRLLDALLAFKPDPNSNPPRLRLPGADMELALRLIENAALRGTNILHADFLIRVFLAVSYRTRVYAVKPENLHSAAITGNRIPVSIDEFESVQRIQTRLASIIRAAKVALGEKEYLDILRVHSDQGEYAKFWNAWGEVALAGIHRGKSFYLFLFNLHAELGDWQQSRTTLLNCIPMMWREDPPVFFDAELAEVVSKCIALAYPDIDDTVQHNLPALIVKTWHHCRTAIQNQKMNERKERLIQTELGTLPEN",
    "output": "Probable mitochondrial mRNA stabilization factor."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAFHWCDNNLHTTVFTPRDFQVELLATAYERNTIICLGHRSSKEFIALKLLQELSRRARRHGRVSVYLSCEVGTSTEPCSIYTMLTHLTDLRVWQEQPDMQIPFDHCWTDYHVSILRPEGFLYLLETRELLLSSVELIVLEDCHDSAVYQRIRPLFENHIMPAPPADRPRILGLAGPLHSAGCELQQLSAMLATLEQSVLCQIETASDIVTVLRYCSRPHEYIVQCAPFEMDELSLVLADVLNTHKSFLLDHRYDPYEIYGTDQFMDELKDIPDPKVDPLNVINSLLVVLHEMGPWCTQRAAHHFYQCNEKLKVKTPHERHYLLYCLVSTALIQLYSLCEHAFHRHLGSGSDSRQTIERYSSPKVRRLLQTLRCFKPEEVHTQADGLRRMRHQVDQADFNRLSHTLESKCRMVDQMDQPPTETRALVATLEQILHTTEDRQTNRSAARVTPTPTPAHAKPKPSSGANTAQPRTRRRVYTRRHHRDHNDGSDTLCALIYCNQNHTARVLFELLAEISRRDPDLKFLRCQYTTDRVADPTTEPKEAELEHRRQEEVLKRFRMHDCNVLIGTSVLEEGIDVPKCNLVVRWDPPTTYRSYVQCKGRARAAPAYHVILVAPSYKSPTVGSVQLTDRSHRYICATGDTTEADSDSDDSAMPNSSGSDPYTFGTARGTVKILNPEVFSKQPPTACDIKLQEIQDELPAAAQLDTSNSSDEAVSMSNTSPSESSTEQKSRRFQCELSSLTEPEDTSDTTAEIDTAHSLASTTKDLVHQMAQYREIEQMLLSKCANTEPPEQEQSEAERFSACLAAYRPKPHLLTGASVDLGSAIALVNKYCARLPSDTFTKLTALWRCTRNERAGVTLFQYTLRLPINSPLKHDIVGLPMPTQTLARRLAALQACVELHRIGELDDQLQPIGKEGFRALEPDWECFELEPEDEQIVQLSDEPRPGTTKRRQYYYKRIASEFCDCRPVAGAPCYLYFIQLTLQCPIPEEQNTRGRKIYPPEDAQQGFGILTTKRIPKLSAFSIFTRSGEVKVSLELAKERVILTSEQIVCINGFLNYTFTNVLRLQKFLMLFDPDSTENCVFIVPTVKAPAGGKHIDWQFLELIQANGNTMPRAVPDEERQAQPFDPQRFQDAVVMPWYRNQDQPQYFYVAEICPHLSPLSCFPGDNYRTFKHYYLVKYGLTIQNTSQPLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVPELCTVHPFPASLWRTAVCLPCILYRINGLLLADDIRKQVSADLGLGRQQIEDEDFEWPMLDFGWSLSEVLKKSRESKQKESLKDDTINGKDLADVEKKPTSEETQLDKDSKDDKVEKSAIELIIEGEEKLQEADDFIEIGTWSNDMADDIASFNQEDDDEDDAFHLPVLPANVKFCDQQTRYGSPTFWDVSNGESGFKGPKSSQNKQGGKGKAKGPAKPTFNYYDSDNSLGSSYDDDDNAGPLNYMHHNYSSDDDDVADDIDAGRIAFTSKNEAETIETAQEVEKRQKQLSIIQATNANERQYQQTKNLLIGFNFKHEDQKEPATIRYEESIAKLKTEIESGGMLVPHDQQLVLKRSDAAEAQVAKVSMMELLKQLLPYVNEDVLAKKLGDRRELLLSDLVELNADWVARHEQETYNVMGCGDSFDNYNDHHRLNLDEKQLKLQYERIEIEPPTSTKAITSAILPAGFSFDRQPDLVGHPGPSPSIILQALTMSNANDGINLERLETIGDSFLKYAITTYLYITYENVHEGKLSHLRSKQVANLNLYRLGRRKRLGEYMIATKFEPHDNWLPPCYYVPKELEKALIEAKIPTHHWKLADLLDIKNLSSVQICEMVREKADALGLEQNGGAQNGQLDDSNDSCNDFSCFIPYNLVSQHSIPDKSIADCVEALIGAYLIECGPRGALLFMAWLGVRVLPITRQLDGGNQEQRIPGSTKPNAENVVTVYGAWPTPRSPLLHFAPNATEELDQLLSGFEEFEESLGYKFRDRSYLLQAMTHASYTPNRLTDCYQRLEFLGDAVLDYLITRHLYEDPRQHSPGALTDLRSALVNNTIFASLAVRHGFHKFFRHLSPGLNDVIDRFVRIQQENGHCISEEYYLLSEEECDDAEDVEVPKALGDVFESIAGAIFLDSNMSLDVVWHVYSNMMSPEIEQFSNSVPKSPIRELLELEPETAKFGKPEKLADGRRVRVTVDVFCKGTFRGIGRNYRIAKCTAAKCALRQLKKQGLIAKKD",
    "output": "Essential for RNA interference (RNAi); double-stranded RNA (dsRNA) induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger. May carry out the initiation step of RNAi by cleaving dsRNA to produce 22 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs. During embryogenesis, involved in germline fate determination."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MYADRDLPGAGGLAVRVIPCLDVDDGRVVKGVNFENLRDAGDPVELAAVYDAEGADELTFLDVTASSSGRATMLEVVRRTAEQVFIPLTVGGGVRTVADVDSLLRAGADKVAVNTAAIACPDLLADMARQFGSQCIVLSVDARTVPVGSAPTPSGWEVTTHGGRRGTGMDAVQWAARGADLGVGEILLNSMDADGTKAGFDLALLRAVRAAVTVPVIASGGAGAVEHFAPAVAAGADAVLAASVFHFRELTIGQVKAALAAEGITVR",
    "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MINLKKYIPEGSRDILFEECTIKNNIENILRNSYINVGYEEVRSPTLEFYDVYNLENQPISQEKMYKLFDNTGRILVLRPDMTTPIARICATKLKNRVYPLKLSYTGNIYRMNKALNGKISEITQSGIEILGFSSLKADAEVIITAIKAILKTGLKNFKIEIGQVEFFKSIISDTALKEQDTEKLRNFIENKNFSKVEEFILRNSDLIGETSSKVLMNLPNLFGGKEVIEKAEQLTSNKQAIEALKKVRDLYDIVKRAGFGEYILIDLGMVQHINYYTGLIFRGYAHGIGDDLLSGGRYDKLLGQFGYDIPATGLAINVDNLVAALDDCVRENLYSRDRYVVFASSCNIEKAYEAVSKLNSEGKRAEVSLFDNIEETKKYCIENKISKIFNADTGKTIVEENYYGQK",
    "output": "Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSTLRLLLSDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDHVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTVSTAIVLAALNSLGVTAEASGRNDLVVKTDSGDRKVSGSAYRETMDRGFHHGTLLLNADLSRLANYLNPDQKKLQAKGITSVRGRVANLVELLPGITHQQVCEAIQEAFFSHYGERVDAEVISPDNTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFRWGGVELHFDVEKGHITRAQAFTDSLNPAPLEALAARLVGCQYRAEVLQQQCEALVGDFPEQEAELKELSAWIAGAVR",
    "output": "Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNHIQDAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLELNTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLIVNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET",
    "output": "Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEKITASVRLKKTRGERNRLLKEGKVPGVMYGKNIEPVAVAVNARELESLVERGLKLFELSVEGKTQRVLVKELQHHPVTGKLIHVDFQVVESGRKIRQLVPVELYGEPAGVKAGGILEHGLSEVTVECLPEDLPEFIEADVSKLEVGDCLRVKDLELPPGVRVIEDPESIIALISAPRDYVEEEEETTTSAPEATA",
    "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKVRKNEEALSEVLVDVNRVTKVVKGGRRFAFSAYVVVGDKAGRVGAGHGKAKEVNEAREKAKQAAKKKMMKVSLYQNRTIHHDVIGRSGAAKVVLRRAKAGTGVIAGGSMRAIFDSLGVHDIVAKSIGSTNVYTMIAATFDALKKLSSPKSIAARRDKKMNEIFIKSSDIQVNE",
    "output": "With S4 and S12 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAGLSRILLSCTLACLLAGQAAQASVDDPTRAGGDNRVRALRADQARRDVLLTACRDDPGHRRGEPDCVNAERAQALQQWQAAAMTSVDAAFSDLAGALRNAAPRRMEAAIVRLTRQLQPLVYSMMTLLVLLTGYALLARRDRPFEWHIRHALLVAVVTSLALSPDRYLSTVVAGVQDVAGWLSGPWTAPDGAAGRGGLAQLDQFAAQAQAWVAQLAGQAANDANPGSAVNWLLCAMIVAASAGGWLCLAASLLIVPGLIVTLLLSLGPLFLVLLLFPALQRWTNAWLGALVRALVFMALGTPAVGLLSDVLAGALPAGLPQRFATDPLRSTMLAATLCATATLMLLTLVPLASSVNAGLRRRLWPNAAHPGLAQAHRQAAARQYAPRPAAAAAAAGPHQAGTYAASATPAPAPARPAPSFPAHAYRQYALGGARRPPPRVRRDDRPAPAPDRRVLPRKPNLP",
    "output": "Component of the type IV secretion system ptl required for secretion of assembled pertussis toxin (PTX) through the outer membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKRSLRRVLRPEERKEVQGVVYRGVGKDMDCSKESFKVDIEGDMCRLEAFIKNRRKLSKYEDENLCLLHHAAAEGQVELMQLIINGSSCEALNVMDDYGNTPLHWAAEKNQVESVKFLLSQGANPNLRNRNMMAPLHIAVQGMYNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKRCMELILAYGEKTGYSREAHINFVNHKKASPLHLAVQSGDLDMIKMCLDSGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVDGNQETLLHRASLFDHHDLADYLISVGADINSTDSEGRSPLILATASASWNIVNLLLSKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFLQMQHIKELVMDEDNDGCTPLHYACRQGAPVSVNNLLRFNVSVHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTTIRSKRWDECLQVFTHDSPSNRCPIMEMVEYLPECMKVLLDFCMIPSTEDKSCQDYHIEYNFKYLQCPLSMTKKVTPTQDVIYEPLTILNVMVQHNRIELLNHPVCREYLLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMAFNSTGIINETISTHEERINTLNSFPLKICMILVFLSSIFGYCKEVVQIFQQKRNYFLDYNNALEWVIYTTSMIFVLPLFLDIPAYMQWQCGAIAIFFYWMNFLLYLQRFENCGIFIVMLEVIFKTLLRSTGVFIFLLLAFGLSFYVLLNFQDAFSTPLLSLIQTFSMMLGDINYRDAFLEPLFRNELAYPVLTFGQLIAFTMFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTNLEKKLPFWYLRKVDQRSTIVYPNRPRHGRMLRFFHYFLSMQETRQEAPNIDTCLEMEILKQKYRLKDLTSLLEKQHELIKLIIQKMEIISETEDEDNHCSFQDRFKKERLEQMHSKWNFVLNAVKTKTHCSISHPDI",
    "output": "Receptor-activated non-selective cation channel involved in pain detection and possibly also in cold perception, oxygen concentration perception, cough, itch, and inner ear function. Shows 8-fold preference for divalent over monovalent cations. Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of irritants, such as allylthiocyanate (AITC) found in mustard oil or wasabi, cinnamaldehyde, diallyl disulfide (DADS) from garlic, and acrolein, an irritant from tears gas and vehicle exhaust fumes (By similarity). Acts also as an ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana (By similarity). Is activated by a large variety of structurally unrelated electrophilic and non-electrophilic chemical compounds. Electrophilic ligands activate TRPA1 by interacting with critical N-terminal Cys residues in a covalent manner, whereas mechanisms of non-electrophilic ligands are not well determined. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLTIAIVGRPNVGKSTLFNRLVGQKLALVDDKPGVTRDRRIHAAKLQDLRFDVIDTAGLEEAGDHTLEGRMRSQTKAAIDEADLILFVFDAKSGITPSDLNFASLVRKSGKPIVLVANKSESKAATGGEYEAWSLGLGEPCPISAEHGLGLSDLRDAIIDAVGSERAFSNNKEEDMTIQPASVGDDIEDLQEEGLIYDESKPIRIAIAGRPNTGKSTLINSMLKQDRLLTGPEAGLTRDSISVDWEWRGRHIKLFDTAGLRRKSKIQEKLEKLSVADTLRAIRFAEVVVIVFDATMPFEKQDLQIADLVIREGRVPVIAFNKWDLIENSQATLIDLHEKCARFLPQVRGLRAVPLSGQYGQGIDKLMENIMMMHRVWNRRISTAKLNQWLEIVVAHHPPPAISGRRLKVKYITQVKTRPPGFMISCSRPKVMPQSYLRYLVNGLRETFDMSGIPVRLSLRASDNPFATRAKKK",
    "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNSLVATPVPPHFYEYSRLSSPHPMSTPTHTPINRKRKADDDGNDHDGRMSASPTNSPAFTPRSLPAPRSFKRSRPNVSGRPLSLPRLLETLDTDALRGILRSMCERHPALADEVIHTSPRPSVSSALQVLRNYQSTLQNSFPLGGNPESDYAYNRVRQPLGNLLDALSDFTPHFLPPHETQASVSLSYLDGATDIIHALPRWHSPQNNIERDSAYDEICKAWILVIREAAKRGGGIQLQYGGWDQKLAKHNQNAGGRLQAAVNELGNSLGWMHGPDSQGYGSSTGGDLVSVREQLLSGTYGLGTPVKVGPW",
    "output": "Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIQIFFLGTGAGSPSKKRKLPAFLVRREGVNILLDCGEGTQYTLMNYKLGINSIKIIGISHMHGDHVFGLLGVIASMGLLDRKETLYILGPRKLKDFLYTSFEYSKFNPSFKIEFIDNYNDENITISTFKTCHTIESQGYLIMEKDRVKIDEEKLEKEKIRDWRVIRKLKEGKTVEYNGKLLKPEDYLVIKRGSKVAYTGDTMPCQSVVDSVKGVDILIHDSTFLDEPSAYTYGHSNVTDAAKIALEASVKLLALTHISPRYEDVSEHLKMARRIFPKSILPDDLSYITIK",
    "output": "Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEESILRMHDKTTLKNMAFNRGLSRRGHNGRNASRMRKQDFIDFIMVQNHRDQSAVLGSDFLGDDMIRIFQEFIMDETFTFNPFIHLMGTIKNSTSKSPVSNQPSPEEDEPIPDLTLKPLEPCTKCECTTCMKNSIKQEENLKVHQNILNLESKIMCVVCQANVRNVVFVPCNHLATCISCSANPLMPKKCPMCRKGCKTTIKIFF",
    "output": "Plays a role early in infection by preventing host cell apoptosis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "SCMKAAPMKEVSIRGQGSLAYPGLWTQGNLETLSGPNDATRGLTSLADTFEHVIEELLDEQQVVQPSKENKDADLYSSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAAEKKTAVDMSGATVTVLEKVPVPKGQLKQYFYETKCSSKGYAKEGCRGIDKRYWNSQCRTTQSYVRALTMDNKKRVGWRFIRIDTSC",
    "output": "Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGTLLALVVGAALVSSAWGGCVEVDSETEAVYGMTFKILCISCKRRSETTAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMVYCYKKIAAATEAAAQENASEYLAITSESKENCTGVQVAE",
    "output": "Regulatory subunit of multiple voltage-gated sodium channel complexes that play important roles in excitable membranes in brain, heart and skeletal muscle. Enhances the presence of the pore-forming alpha subunit at the cell surface and modulates channel gating characteristics and the rate of channel inactivation. Modulates the activity of a variety of pore-forming alpha subunits, such as SCN1A, SCN2A, SCN3A, SCN4A, SCN5A and SCN10A."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQKDALNNVRITDEQVLMTPEQLKAAFPLSLAQEAQIAQSRGIISDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTTVGWKGLINDPHMDGSFDVEAGLKIARQLLVELVNMGLPLATEALDPNSPQYLGDLFSWSAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQVALLQTQGNPHGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDYRRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWEMTDALLREIHKDLSGQLAVRVA",
    "output": "Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIDTVEYAATTPDQPQPFAELGLREDEYQRVREILGRRPTDTELAMYSVMWSEHCSYKSSKVHLRYFGETTTEEMRTGMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADALDTRRVLDGVVRGIGGYGNSLGLPNIGGETVFDSCYDGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGACTGLDGIGGVSVLASDTFDAEGARKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAGLSCATSELASAGDVGMAIQLDTVPRRAKDMTPAEVFCSESQERMCAVVAPENVDAFLAVCRKWEVLATVIGEVTDGDRLRITWHGETVVDVPPRTVAHEGPVYQRPVSRPESQEALNADSSKGLPRPVSGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADAGVLRIDESTGRGIALSTDASGRYTRLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGVMWQFAQAVRGLADGCAALKIPVTGGNVSFYNQTGAVAILPTPVVGVLGVLDNVARRIHTSLGTEPGEILMLLGDTYDEFDGSVWAQVMAGHLGGLPPMVDLAREKLLAEVLSSASRDELVSAAHDLSEGGLAQAIVESALAGETGCRIALPEDADPFVMLFSESAGRVLVAVPRPEESRFRSMCEARGLPAMRIGVVDQGSDSIEVRGQFTVSLAELRMTFEAVLPRFFG",
    "output": "Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTMTDPIADFLTRLRNANSAYHDQVKAPHSKLKANIAEILKREGYIADYRTEDAQVGKTLVVDLKYGPSRERSLAGVRRVSKPGLRVYAKSTNLPKVLGGLGVAIISTSQGLLTDKQAAKQGVGGEVLAYVW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSRGSGGGYDRHITIFSPEGRLFQVEYAFKAVKAAGITSIGVRGKDSVCVVTQKKVPDKLLDQTSVSHLFPITKYLGLLATGMTADARTLVQQARNEAAEFRFKYGYEMPVDVLSKWIADKSQVYTQHAYMRPLGVVAMILGIDEEKGPQLFKCDPAGHFFGHKATSAGSKEQEAINFLEKKMKNDPAFSYEETVQTAISALQSVLQEDFKASEIEVGVVKKEDPIFRVLTTEEIDEHLTAISERD",
    "output": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTREVVVVSGVRTAIGTFGGSLKDVAPAELGALVVREALARAQVSGDDVGHVVFGNVIQTEPRDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGAESMSRAPYLAPAARWGARMGDAGLVDMMLGALHDPFHRIHMGVTAENVAKEYDISRAQQDEAALESHRRASAAIKAGYFKDQIVPVVSKGRKGDVTFDTDEHVRHDATIDDMTKLRPVFVKENGTVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGVDPKAMGIGPVPATKIALERAGLQVSDLDVIEANEAFAAQACAVTKALGLDPAKVNPNGSGISLGHPIGATGALITVKALHELNRVQGRYALVTMCIGGGQGIAAIFERI",
    "output": "Required for efficient production of poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) (PHBV). Catalyzes the condensation of acetyl-CoA and propionyl-CoA to form beta-ketovaleryl-CoA, and the condensation of two acetyl-CoA molecules to form acetoacetyl-CoA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEIENIVANTVYIKARESGGQKKGKSKKWKNYLQFPHYTECIPQKKENGEPYAFVVEKQPIGKLLFHEFCQATNPQYHQCCQFQTKVEEYETSDDDGQSRRDLASAIVALLSSKNDQDLSSSIDEEVWCAFLSDEVISTCISTADSATHDSEPRSDIFSEPYRLTREYLKQKPFAEFIQTMYFHRFLQWKWLEKRPVDKHTFRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLNEKQILQKVNSPFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGGFDEKRVQFYAAEITLGLQHLHLEHILYRDLKPENILLDDFGHVRISDLGLAVELKDNEPIKGRVGTVGYMAPEIVKNERYTYGVDWWGVGCLIYEMIEGKAPFRQRKEKVKREEVERRVREDQEKYSEKFSEAARTLCRGLLHKEPGFRLGCRRVGKPEDGAEEIRAHPFFNTADTATGREPVPWKKMEAGKVTPPFCPDPRAVYAKDVLDIEQFSTVKGVRLDATDTQFYGKFNTGCVSIPWQSEMIETECFAELNTFYEEDGSLVWNLRPDGINMEERRNGTSKPGFFSRLFRKKNIEVTKSLHDLSRLGVDQQQPSTSAKPAAVRSSRAASASGRTSMI",
    "output": "Specifically phosphorylates the activated forms of G protein-coupled receptors."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLDIQQLRSNLQNIITRLAQRGYDFPVADFESLESQRKSVQTLTQTLQAKRNSASKQIGIARQRGEDVSLIMAEVANMGDELKQAENQLEAVQTRLQQLLLEIPNLPHDSVPAGKDENDNLEMRRWGTPKTFDFPVQDHASIGEHLKLIDFETAAKLSGARFSLLKGGLARLHRALAQFMLDTHTQENGYNEIYVPYLVNADCLRGTGQLPKFEQDLFAVRSGAQEEADNPDKTGPAGLHLIPTAEVPLTNIVRNTIVPLENLPLQFVAHTPCFRSEAGSYGRDTRGLIRQHQFDKVELVQITHPEKSHEALESLVGHAEKILQKLELPYRVMLLCTGDMGFSAAKTYDIEVWLPAQQAYREISSCSNCEAFQARRMQARFRKGQEKPELLHTLNGSGLAVGRTLVAILENYQNEDGSITIPEILRAYMGGIERIGL",
    "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSSVVNAAYAEYNGKEKGDQEDPRVLIPQLCRLFYELGWVTGTGGGISLRHGEHIYIAPSGVQKERIQPEDLFVCDIDEKDISCPPPQKKLKKSQCTPPFMNAYTMRGAQAVIHTHSKSAVMATLLFPGKEFRITHQEMIKGIRKGNSGTNFRYDDTLVVPIIENTPEEKDLKERMARAMDMYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVQMKQSGLDPSAFPTEEKGIV",
    "output": "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARTTPISRYRNIGIVAHVDAGKTTTTERVLFYTGKSHKMGEVHDGAATTDWMVQEQERGITITSAAITAFWKGSEKQYKDEHRFNVIDTPGHVDFTIEVERSLRVLDGAVVVFCGTSGVEPQSETVWRQANKYGVPRLVYVNKMDRAGANFLRVIGQIKQRLGHTPVPIQLAIGSEDNFQGQIDLLTMEAVYWNDADKGMVPVRKPIPAELQELADEWRNNMVEAAAEANEELMNKYLEGEELTNVEIKAALRQRTIAGEIVLAVCGSSFKNKGVPLVLDAVIDYLPAPVDIPAIKGTDPDDETIELERHADDAEPFSALAFKIATDPFVGTLTFVRVYSGVLNSGDGVINSVKGKKERVGRMVQMHANAREEIKEVRAGDIAALIGMKDVTTGETLCNADKPIILVRMDFPEPVISVAVEPKTKDDQEKMGIALGKLAQEDPSFRVKTDEETGQTIISGMGELHLDILVDRMRREFNVEANIGKPQVSYRERITKNCEIEGKFVRQSGGRGQFGHCWIRFAPADEGQEGLQFVNEVVGGVVPKEYIPAIQKGIEEQMKNGVVAGYPLIGLKATVFDGSYHDVDSNEMAFKVAASMATKQLAQKGGGELLEPIMAVEVVTPEDYMGDVMGDLNRRRGMILGMEDTVSGKVIRAEVPLGEMFGYATDVRSMSQGRASYSMEFKKYNTAPAHIAETVSKKQG",
    "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLDMGDRKEVKMIPKSSFSINSLVPEAVQNDNHHASHGHHNSHHPQHHHHHHHHHHPPPPAPQPPPPPPQQQQQPPPAPQPPQARGAPAADDDKGPQPLLLPPSAALDGAKADALGAKGEPGGGPAELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGDKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQTSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSDYFTHQNQGSSSNPLIH",
    "output": "Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKKVAVIGAGVSGLTSIKCCLDEDLEPTCFERSNDIGGLWKYTETSKDGMTRIYWSLVTNVCKEMSCYSDFPFQEDYPNFMSHSKFWNYLQEFAEHFDLLKYIQFKTTVCSVTKRPDFSKTGQWDVVTETEGKQHRAVFDAVMVCTGKFLNPRLPLESFPGILKFRGQILHCQEYKIPEGFRGQRVLVIGLGNSGGDVAVELSRVAAQVLLSTRTGTWVISRSSNGGYPFNMMITRRCLNVIEQVLPSCFLRWINERQMNKRFNHENYGLSITKGKNPKFIVNDELPTCILCGTVTVKTSVKEFTETSAIFEDGTVEENIDSVIFTTGYVFSFPFLEEPLRSLCMKKMFLYKHVFPSNLERASMAIIGLISLKGSILTGTELQARWATRVFKGLCKIPPPQQLMAEVTKKEELIKRGVIKDTSEEKLSYIPYMDDLAACIGTKPNIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWDGARNAILTQWDRTLKPLKTRTVSSDSSKSASLSHYLKVWGAPLLLASVLLICKSSHFLKSVRDKLQNRIFPYLVL",
    "output": "This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKEILITNDDGFEATGLLALKEALSELDGVNVTIVAPSSEKSACAHSLTLTRPLRFIKLDDNFFKLDDATPSDCVYLALHALYNKKPDLVISGINHGANLGEDITYSGTCGAAMEGVLQGIRSIAFSQFYENNSLNELGFELAKEVVKFITPKVLNDEISLNPREFLNVNIPATTSKNFKGYAVVPAGRRTYATHATLNRNPRGIEYYWLGNAALEYEKGEPSDISKVNEGFATITPIKLNMTSYESLESLKGKFDAK",
    "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAAKDVKFGDSARKKMLVGVNVLADAVKATLGPKGRNVVLAKSFGAPTITKDGVSVAKEIELKDAFENMGAQLVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKATAAIVAELKNLSKPCADSKAIAQVGTISANSDNSIGEIIAEAMEKVGKEGVITVEEGSGLENELSVVEGMQFDRGYLSPYFVNKPDTMVAELEGPLLLLVDKKISNIRELLPVLEAVAKAGRPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGQVISEEIGLSLETATLEHLGNAKRVILSKENTTIIDGAGADGDIEARVKQIRAQIEETSSDYDREKLQERLAKLAGGVAVIKVGAGTEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRALAAIADLKGDNEEQNVGIALLRRAVEAPLRQITANAGDEPSVVADKVKQGSGNFGYNAATGEYGDMIEMGILDPAKVTRSALQAAASIGGLMITTEAMVADLPEDKPAAGMPDMGGMGGMGGMM",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATYHHWTVGQALALFDKPLLELLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLESERLMQVEQVLESAKKAKAAGSTRFCMGAAWKNPHERDMPYLAKMVEGVKALGMETCMTLGSLSKQQAHRLADAGLDYYNHNLDTSPEFYGSIITTRSYQERLDTLNEVRDAGIKVCSGGIVGLGETVRDRAGLLVQLANLPKPPESVPINMLVKVKGTPLENNAEVDAFEFIRTIAVARIMMPSSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPDEDKDLQLFRKLGLNPQQTATSHGDREQQQALTEQLLHGDTAQFYNAAV",
    "output": "Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSAATPLIVQQAEAEQLLARIDVLQAMRQLFLDLAAGQALQPAQQLVEFPAGRGDFINYLGVLAQEQVYGVKTSPYIVREQGPLVTAWTLLMSMQTGQPLLLCDAARLTTARTAATTAVAVDALAPAEACRLALIGSGPVAHAHLQYVKGLRDWQGVRVHSPCLDERRLQSLRAIDPRAEAAGSLEEALDEADVILLCTSSARAVIDPRQLKRPALVTSISTNAPRAHEVPAESLAAMDVYCDYRHTTPGSAGEMLIAAEQHGWSPEAIRGDLAELLSAQAPRPEYRRPAFFRSIGLGLEDVALANALYRLRQAG",
    "output": "Involved in the anabolism of D-lysine and D-arginine. Under aerobic conditions, the arginine succinyltransferase (AST) and arginine transaminase (ATA) pathways are 2 major routes for L-arginine utilization as the sole source of carbon and nitrogen. The D-to-L racemization of arginine by DauA and DauB is necessary, before to be channeled into the AST and/or ATA pathways. DauB catalyzes the synthesis of L-arginine from 2-ketoarginine (2-KA) and ammonium."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVEDKKTDDYTIEMDKMDQGSKNFEAAAPPPQPRTPPAGSISNNPILPVLAYCGSSILMTVMNKYVLSGLDFNLNFFLLCVQSIVCIVAIQTCKSCGLITYRDFSADEARKWFPITLLLIGMIYTGSKALQFLSIPVYTIFKNLTIILIAYGEVLWFGGSVTGLTLFSFGLMVLSSIIAAWADIKHAVESTGDATAKVSTLNAGYIWMLVNCLCTSSYVLGMRKRIKLTNFKDFDTLAMFYNNLLSIPVLIVLTGLMEDWSSANITRNFPPADRNNIIFAMILSGLSSVFISYTSAWCVRVTSSTTYSMVGALNKLPIALSGLIFFDAPVTFPSVSAIVVGFVSGIVYAVAKIKQNAKPKTGVLPMSNPPVSASSQSMRDSLRS",
    "output": "Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKQLTSSQVRQMFLDFFKEHGHMVMPSASLIPQDDPTLLWINSGVATMKKYFDGSVVPKNHRITSSQKSIRTNDIENVGKTARHQTFFEMLGNFSVGDYFKKEVIPWAWEFLTSPKWLGLDPDKLYVTVYPKDTEAYHMWHDVVGLPEDHIVKLEDNFWDIGEGPCGPDSEIFYDRGQENNDVAEDDPENFPGGENARYLEIWNIVFSQFNHLPNGKYVDQPHKNIDTGMGLERVVSIIQDAPTNFETDLFMPIIKETEKLSDGKKYAANKEDDVAFKIIADHVRAVSFAIADGALPSNSGRGYVLRRLIRRADLNGQRLGIKGAFLYKLVPVVGEIMKSHYPEVVDQQAFIQKVIKNEEERFQVTLSSGLNLLDNIIAEAKKSDDKTVSGKDAFKLFDTYGFPYELTFEAAQDAGLKVDKKGFDEEMKAQKERARKARGNLQSMGSQDVTLMNIKDKSEFEYGTLEEKHAKLIDIVVNDKLVDKADGEHATLIFDKTPFYAERGGQVADHGEILNQNGELVARVTDVQHAPNDQNLHFVDIILPLEKGQEYILKVDQKRRRGLKHNHTATHLLHAALREVLGTHTHQAGSLVEPDYLRFDFTSLEPMTKKEIANVEKIVNEKIWEEIPVKTTVTDPDTGLKMGALALFGEKYGDTVRVVQIDDFSTEFCGGTHCENTDQIGMLKIVSESAVGAGTRRIIAVTGPEAYKYVTDRDEILKEVQDEVKATKAEDVTNKISSLEEDLRASQKEAEQLKAQINKAKAGDLFNDVKQVKGLTVIAAQADVEGMNDLRELADNWKSSDKSDVLVLAAEVNGKANMVISLNDKAIKAGLKAGDLIKTAAPIFGGGGGGRPNMAQAGGKNPAGLKDAIAKVLQEVEEKQN",
    "output": "Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAHVITRINAREILDSRGNPTVEVDLETNLGIFRAAVPSGASTGIYEALELRDNDKSRYLGKGVQKAIKNINEIIAPKLIGMNCTEQKKIDNLMVEELDGSKNEWGWSKSKLGANAILAISMAVCRAGAAPNKVSLYKYLAQLAGKKSDQMVLPVPCLNVINGGSHAGNKLSFQEFMIVPVGAPSFKEALRYGAEVYHTLKSEIKKKYGIDATNVGDEGGFAPNILNANEALDLLVTAIKSAGYEGKVKIAMDVAASEFYNSENKTYDLDFKTPNNDKSLVKTGAQLVDLYIDLVKKYPIVSIEDPFDQDDWENYAKLTAAIGKDVQIVGDDLLVTNPTRITKALEKNACNALLLKVNQIGSITEAIEACLLSQKNNWGVMVSHRSGETEDVFIADLVVALRTGQIKTGAPCRSERNAKYNQLLRIEESLGNNAVFAGEKFRLQLN",
    "output": "Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as parasite development and invasion (By similarity). Plays an essential role during ookinete invasion of the mosquito vector midgut by mediating the interaction of the ookinete with the midgut epithelium and, further, by binding to mammalian host plasminogen in the blood meal, whose conversion to active plasmin promotes the invasion process (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAFALPSSLVSVCDKSFIKPSSLTPSTLRFHKLSFIDQSLSNMYIPCAFFYPKVQQRLEDSKNSDELSHIAHLLQTSLSQTLVSYYPYAGKLKDNATVDCNDMGAEFLSVRIKCSMSEILDHPHASLAESIVLPKDLPWANNCEGGNLLVVQVSKFDCGGIAISVCFSHKIGDGCSLLNFLNDWSSVTRDHTTTTLVPSPRFVGDSVFSTKTYGSLTTPQILSDLNECVQKRLIFPTDKLDALRAKVAEESGVKNPTRAEVVSALLFKCATKASSSMLPSKLVHFLNIRTMIKPRLPRNTIGNLSSIFSIEATNMQDMELPTLVRNLRKEVEVAYKKDQVEQNELILEVVESMREGKLPFENMDGYENVYTCSNLCKYPYYTVDFGWGRPERVCLGNGPSKNAFFLKDYKAGQGVEARVMLHKQQMSEFERNEELLEFIA",
    "output": "Participates in the biosynthesis of capsaicinoids in pungent cultivars of Capsicum chinense. Capsaicinoids, the alkaloids responsible for the heat or pungency of chili pepper, are synthesized from phenylpropanoid intermediates in the placental tissue of chili peper fruit. Can transfer an acyl from 8-methylnon-6-enoyl-CoA to vanillylamine forming capsaicin and CoA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKIIGIDLGTTNSCVAVMEGDKPKVIENSEGHRTTPSIVAFTDDNEILVGQSAKRQSVTNPEKTLFAIKRLIGRRFDDPIVQKDIKMVPYKIMKADNGDAWVRVKDQDKAPPQISAEVLRKMKKTAEDYLGEEVKEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAYGMDKKRGDSVIAVYDLGGGTFDISIIEIAEVDGEHQFEVLATNGDTFLGGEDFDLALIEYLASEFKKDTGIDLHNDPLALQRLKEAAEKAKIELSSAQQTDVNLPYITADASGPKHLNIKLTRAKLESLVEKLVERTIEPCKTALKDAGLTVSQINEVILVGGQTRMPLVQKTVEEFFGKEPRKDVNPDEAVAVGAAIQAAVLSGEVKDILLLDVTPLSLGIETMGGVMTKLIEKNTTIPTKATQVFSTADDNQTAVTVHVLQGEREQASANKSLGRFDLRDIPPAPRGVPQIEVTFDIDANGILNVSAKDKATGKAQSIVIKASSGLSEEEVAAMVKDAQSHAEEDKKFKEMAELRNQADSLIHSCEKSMKDLADELSEDEKRGIETAISELKEAVQGTDKARIEDKLKVLTDASAKMAERIYAKKSSEGQAAQGQTQSQESTKPAEEGVVDAEFEEVKEEDKK",
    "output": "Acts as a chaperone."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVIQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMDFAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDEDNVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTNRQLFNQIRGMNPWPVAHAFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD",
    "output": "Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLVLGIESSCDETGVALVDAGGSEVPRLLSHALFSQIQMHQAYGGVVPELASRDHIRRVLPLTRQVMAQAGRSLAQVDVVAYTRGPGLAGALLVGAGVACALAAALGKPVMGVHHLEGHLLSPFLSADPPVFPFVALLVSGGHTQLMRVDRVGSYELLGETIDDAAGEAFDKSAKLMGLPYPGGPHLADLARQGDGTAFKLPRPLLHSGDLDFSFAGLKTAVLTQAKKLGPELENRKADLAAATQAAIVDVLVKKSLAAMAQTGLKRLVVAGGVGANALLRSQLNAACQQRGIRVHYPELHLCTDNGAMIALAAGMRLQAGLETLQRGYTFDVKPRWSLTPTVARSA",
    "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSASRFVKCVTVGDGAVGKTCLLISYTSNTFPTDYVPTVFDNFSANVVVNGSTVNLGLWDTAGQEDYNRLRPLSYRGADVFILAFSLISKASYENVSKKWIPELKHYAPGVPIVLVGTKLDLRDDKQFFIDHPGAVPITTAQGEELRKQIGAPTYIECSSKTQENVKAVFDAAIRVVLQPPKQKKKKSKAQKACSIL",
    "output": "May be involved in cell polarity control during the actin-dependent tip growth of pollen tubes. May regulate callose synthase 1 (CALS1) activity through the interaction with UGT1.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATAASNPYSILSSSSLVHADSAVMQQGSPFRNPQKLLQSDYLQGIPSNGHPLGHHWVTSLSDANPWSSLASSPLDQQDIKPGREDLQLGAIIHHRSPHVSHHSPHNNHPNTWGASPVHNSSGQPINVYSQPGFTVSGMLDHGGLTPPPPSGTTQSLHPVLREATDHGDLGSHHCHDHSDEETPTSDELEQFAKLFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAALEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDPQQHEIYSHSVKTDTSCNEL",
    "output": "Transcriptional activator. Induces neural-specific gene expression to act as a key regulator of neural differentiation (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTRVKRGYVARKRRRSILCQRAGSRGAHSILFRNAQQQNMKAMIYSHEHRKKRKRDFRSLWVTRINAAVREQGLSYNKFIFLLKTHKVLLNRKMLAQIAILDITSFKKLLLVIN",
    "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSAAQGWDRNRRRGGGAAGGGGGGSGAGGGSGGNGGRGTGQLNRFVQLSGRPHLPGKKKIRWDPVRRRFIQSCPIIRIPNRFLRGHRPPPARSGHRCVADNTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGVWHQMGTDGYMPRELASMSLVLHGNNLLVFGGTGIPFGESNGNDVHVCNVKYKRWALLSCRGKKPSRIYGQAMAIINGSLYVFGGTTGYIYSTDLHKLDLNTREWTQLKPNNLSCDLPEERYRHEIAHDGQRIYILGGGTSWTAYSLNKIHAYNLETNAWEEIATKPHEKIGFPAARRCHSCVQIKNDVFICGGYNGEVILGDIWKLNLQTFQWVKLPATMPEPVYFHCAAVTPAGCMYIHGGVVNIHENKRTGSLFKIWLVVPSLLELAWEKLLAAFPNLANLSRTQLLHLGLTQGLIERLK",
    "output": "Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation. The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms. The CRL2(KLHDC10) complex specifically recognizes proteins with a proline-glycine (Pro-Gly) at the C-terminus, leading to their ubiquitination and degradation (By similarity). Participates in the oxidative stress-induced cell death through MAP3K5 activation. Inhibits PPP5C phosphatase activity on MAP3K5. Acts as a regulator of necroptosis (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSMSGSDFGAPCDDPKIFRNICRDRILKDLLQPDKDKETKSSWKVLIMDKFTVRIMAYACKMAEITDAGISLVEDLFKRREPMPSMDAIYFLQPLKENVIMLLSDMSGRCPLYRKAYIFFSSPIPKELVSYIKNDSSVIPRIGALREMNLEFFAIDMQGFTTDHDMAFTDLYSAQHNSKKFNDTISTMATRIATTFASLKEFPCVRYRAPKGTDPMTTPKFDMVPKWLATAVWDIVSKYKSTIPEFPQKETCELLIVDRPIDQIAPVIHEWTYDAMCHDLLEMDGQKYIYEVSKAGSEPERKEALLEDHDPLWVELRHIHIADASERLYDKMNNFVSKNKAAQLHSRDGGEISTKDLQKIVQALPQYGEQVEKLTLHIEIAGKINKFIREYGLRDIGQVEQDLVFGDAAAKEVISILRSKQDMSPENKLRLLIIYAIVYPEKFEGDKGEKLMQLAKLPHDEMDAINSLRYLVGSDTKKASRPGGFSLKFDAQKKKNAARTERQDGDETWALSRFFPLIEELIEKLSKGALPLNEYPSMSEPSSTEQGSTQSAAATKPAQAQPMSRRSRRTPTWAKSRNSDDSQSSDSSVLRHGSNDFKRLGNRIFVFMIGGATRSELRTVHKLTMKLKREIVLGSSSIDDPPQFISKLKMLTAGGANDV",
    "output": "Involved in the vesicle trafficking. Binds syntaxins (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MYPSNKKKKVWREEKERLLKMTLEERRKEYLRDYIPLNSILSWKEEMKGKGQNDEENTQETSQVKKSLTEKVSLYRGDITLLEVDAIVNAANASLLGGGGVDGCIHRAAGPCLLAECRNLNGCDTGHAKITCGYDLPAKYVIHTVGPIARGHINGSHKEDLANCYKSSLKLVKENNIRSVAFPCISTGIYGFPNEPAAVIALNTIKEWLAKNHHEVDRIIFCVFLEVDFKIYKKKMNEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDAGAQDEAKEQRNGTK",
    "output": "Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety . Inactive towards proteins bearing poly-ADP-ribose . Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTTDKDKMAVGRLKSRPQFLAVRAGESRRGPLFLLEVLDRNDPEGEARVGFTVTKKHGNAVERNRMRRRLKEAVRLSAGFAMKPGHDYVIVARRDLLNAPFDALTRALRDRIENKPKQKRPPAGSRKS",
    "output": "RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQTWSGVPIIAANMDTVGTFEMAQALAGFDILTAVHKHYTVEEWAAFINTASADVLKHVMVSTGTSDADFEKTVQILALNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTMPGDVAKAFGGGADFVMLGGMLAGHEESGGSVVEENGEKFMLFYGMSSESAMNRHVGGVAKYRAAEGKTVKLPLRGPVGNTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNSL",
    "output": "Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEKSSSSLIDPPSLSGDEIRDAFINFFVQHNHKKLASSSLIPDDPTVLLTIAGMLPFKPIFLGLKESSTPRATSSQKCIRTNDIENVGRTARHHTFFEMLGNFSFGDYFKKEAIQWAWELSTEVFRLNPQNIVISVFKEDLEAEQIWKEVVGVDANRIIRMGAADNFWSSGATGPCGPCSELYFDFKPELGSDEIDLEDDSRFIEFYNLVFMQYNRDLKGNLEPLANCHIDTGMGLERMAQILQKKSNNYETDLIFPLINAAALLAQIKYETTNKKNKTSLKIIGDHCRAVTHLICDGVSASNLGRGYILRRLIRRMIRHGRLVGIIQPFLPQLAEIAIELMKNAYPQLLEKKKIILNELKIEESRFLETLERGEKLLAEITSHECDLISGAQAFELYDTYGFPLELTEEIANEKGISVDINGFENEMAKQRKRAKEASVSIDLTEEGSIEREISLFDDTRFEGYEKLETTSTVIGIFKNNESVKQAVQGDLVKIIVNRTPFYAESGGQIGDKGLITSQDLEVSVENVRKKKNIFIHSGIVNTGVLEINSSVQMNVTPSFRQRTTSNHTATHLLQSALKLSIDSSVSQRGSLVSNHRLRFDFNAPKPLTIKELEDMEARINQWINEDHLIQIKTMPIKEAMAAGALAMFGEKYGDVVRVVDVPGISMELCGGTHVTRTSQLGTFKIINETGIASGIRRIEAIAGPSVLDYFNERDLVVKELSKSFKVQSYEIVERVSSLQLELKDKTKELIKVKNELALAKALGLATYAKSVGKSKLLIRRLDGVDGSGLQSAASSLIDHLGKYSAVIFGGIPNQEIDNKLVFVAAFSPDLVSDGLHAGKFISGVAKMCGGGGGGRPNLAQAGGSQPQSLDLALEKANENLTQQLS",
    "output": "Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDDNKPKSNTFTDEGRLPQVEFAIKNVSRAGTIIGYVCSDGVVLMGVNKEPTNGPMEKIYQLSDSIYCVLCGLFGDAMELKRYARIKAQEVLERFGVECPLTTLCKFVGQRKQAFTQYAGTRPFGVSFLYAGVIDGKYALMSTDPSGTSNRWKGMCYGENEEAINRGLKNDFPEDEMDMKTATVEILRLLGKARELGPKEADRLEILHFSKDCKKYLPCDEVLKLLEEIHAK",
    "output": "The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQKRLTLLGSTGSIGDSTLDVVARHPERFSVYALTAHRNGDKLVEQCLRFAPEVAVVGDAATAAHVDAKLRAAGSKTVVLHGPQALVDVSKSDGCDTVVAAIVGAAGLAPSLAAARAGKRILLANKEALVMSGAIFMDAVRDHGAILLPVDSEHNAIFQCMPRDAAEHGGISKIILTASGGPFRTREPATLVDVTPDEACKHPNWVMGRKISVDSATMMNKGLEVIEAHWIFGLPGDRIDVLIHPQSVIHSLVSYRDGSVLAQLGNPDMRTPIAHALAFPERVDAGVDQLDLAQIAQLSFEKPDYARFPCLALALKALEEGGIASAALNAANEVAVEAFLERRIGFMAIAATVDAVLNTLPNRAPDGLDDVLAADAEARRLAAAIIAKAPAPRVERTV",
    "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATARPSIVGPDSGPESPFPYKMEGKVISGFGRGSKELGIPTANLPVDATISPWISSISSGVYYGWASLQLPPSHPESPSSSSCSPYVVFPMVMSIGYNPFYNNTERSAEVHILHKFTADFYDAPMRLLILGFIRDEKNYDSLEALVKDINTDCDVARTSLDRKAWVPQGGLLHPAVDVREKQGDLDGSWLVRPNDSPSA",
    "output": "Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVAVLQSTLPIIFSMEFIMGTLGNGFIFLIVCIDWVQRRKISLVDQIRTALAISRIALIWLIFLDWWVSVHYPALHETGKMLSTYLISWTVINHCNFWLTANLSILYFLKIANFSNIIFLYLKFRSKNVVLVTLLVSLFFLFLNTVIIKIFSDVCFDSVQRNVSQIFIMYNHEQICKFLSFTNPMFTFIPFVMSTVMFSLLIFSLWRHLKNMQHTAKGCRDISTTVHIRALQTIIVSVVLYTIFFLSFFVKVWSFVSPERYLIFLFVWALGNAVFSAHPFVMILVNRRLRLASLSLIFWLWYRFKNIEV",
    "output": "Putative taste receptor which may play a role in the perception of bitterness."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAYPFQMGLQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLSFDSYMIPTQELKPGELRLLEVDNRVVLPMELTIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMAMRPGLYYGQCSEICGSNHSFMPIVLELVPLSHFEKWSASLL",
    "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMLRSQAKNVDLTSQADSRHQQKRKQAEQLDALKNPSEPAAKKQHSKGLTELRAHISGFKIDSAKRDPLGKSRTSRRDVENLPPQKSRYVDPCPHYDYDLEEAGNPDSISDYAQGIFDYYRHREVHFRVRKYLHKHPEVDVKTRAILIDWMVEIQETFELNHETLYNAVKLTDMYLCKTKNVDKNTIQKLACVAIFIAAKYDERSPPLVDDLIYLSGDRFSRDELLAMERELFATVGYDLGSPLSYRYLRRFGRVCRVDMKTLTMGRFILETSLMVYEYAMVSQSRLAAAAFVLAMRMLDKNNEYEWNPVLEKYSGFTGEEVMPLVEHMNHILHFSKDKWAQLTSVRQKYSHEVFFHVASIPMLPDTLKVVDSHTYAPVPMLSYP",
    "output": "Could be involved at the G2/M (mitosis) transition (Probable). Interacts with the CDK1 and CDK2 protein kinases (Probable). G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis (Probable). Plays a role during oocyte meiosis II ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKQFVRSAKNMMKGYSSTQVLVRDATANDSRTPSIDTLDDLAQRSYDSVDFFEIMDMLDKRLNDKGKYWRHVAKSLTVLDYLVRFGSENCVLWCRENFYVIKTLREFRHENESGFDEGQIIRVKAKELVSLLNDEERLREERSMNTRNRRANRAARPRPRRQRTRSNPHDSSPSYQDDLEKALEESRITAQEDEQRRRELAQYDDEDPDFQAALQLSKEEEELKQLQELQRLQKQQQSLSQFQAPLQQQQPQQQPAYYDIFGNPISQDEYLQYQYQQDQEQAMAQQRWLDQQQEQQQLAEQQYFQQQQQAAAAASALQQQQTAANMQQQQQQPADFQQPLPTGSNNPFSMDNLERQKQEQQHAQLQRQQEEARQQQEQLKLQQLQRQQQEEAQLHQKRQEEAQLQQQQAQLLQQQAQFQQQQPLKQTRTGNQSISDKYSDLNTLLATGTGIDTFGNTGEARIPAQHTKTGTFINSQGTGYKQVTNEPKNNPFLSNQYTGLPSTNIVPTQTGYGFGNQPQSPPTNSPQQNPTGISYSQPQQQQQPQQQPQYMQNFQQQQPQYAQNFQQQPQYTQNYQQQPQYIQPHQQQQQQQQQQQQQQGYTPDQGVSLIDL",
    "output": "Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSVVTQDDYFKDKRVHHFRRSRAMLKSV",
    "output": "RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MITAVNRPAALHINLAAIKENTRQAKAHLKPGQKLFCVVKANAYGHGAARLAPVMEEAGADGFCVAMLDEGLELRRAQIVKPILVLGLQPAEESALAAANDISLPVSSLDWLKKAEKVLRKEGLQLKIHLAIDSGMGRIGFSEDEDFKAVNEYLQGNDAFFVEGMFTHFASADSADASYFDYQVKRFKHMESLLTVKPKWIHVDNTAAILFDKDVASDIVRFGIGLYGLNPSSAPGSRDLEPAFALEPAMSFVSELTYVKQIHKGYGVGYGSTHIAEEDEWIGTVPVGYADGWIRKFQGFKVKVGDTYCPIVGRVCMDQFMVLLPKEVPAGTPVELISADPAAPNSLRRAADWLDTIHYEVACQFNDRLDRIYDNE",
    "output": "Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MANIQGGQQIGTNQGKGQSAADKLALFLKVFGGEVLTAFARTSVTMPRHMLRSIASGKSAQFPVIGRTKAAYLKPGENLDDKRKDIKHTEKVIHIDGLLTADVLIYDIEDAMNHYDVRAEYTAQLGESLAMAADGAVLAELAGLVNLPDGSNENIEGLGKPTVLTLVKPTTGSLTDPVELGKAIIAQLTIARASLTKNYVPAADRTFYTTPDNYSAILAALMPNAANYQALLDPERGTIRNVMGFEVVEVPHLTAGGAGDTREDAPADQKHAFPATSSTTVKVALDNVVGLFQHRSAVGTVKLKDLALERARRANYQADQIIAKYAMGHGGLRPEAAGAIVLPKGVGVIPDPTGVTLSQKTMTLVEGASRALTGTVQPSDANQSLSWSSSAEDVAVWEAGKVVAKGVGTADITATTSNGLIASCKVIVNAATS",
    "output": "Assembles with the major capsid protein to form an icosahedral capsid with a T=7 symmetry, about 60 nm in diameter, and consisting of 415 capsid proteins. The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively. Once the capsid is formed, encapsidates one single copy of the viral genome."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEKTQDRDTLSGRMEAEGSLNSEELPPHPQSPPPPPSPRSPTSPVTPELPQPNAPTEVEARQLLVEEWGPLSGKLELPPRISWQLLFLERPLYRNLLSSPNPEGINIYQPAPPTGPTRKPLKELGNFRGWYITTQNLQGPLSWTVKEQCVNLLAKKLWEELLDDEQPDITIMDWFEDSRLDQCVYELHVWLLAADRRTVIAQHHVAPRTNGRGPPGRWIQVSHVFRQYGPGVRFVYFQHKAKNRMEPGGLRRTRVTDSSVSVQLRE",
    "output": "Promotes cell proliferation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNDVVKVGMADLNVVTPPHTIRTAGLGSCVGVVLYDDVKKVAGMAHIMLPDSALGKKQEFNRAKYADTALDLLLSKLEAIGAKRYSLKAKMAGGAQMFSFASNNDMMRIGQRNVEAVKKKLRELSIPILAEDVGGSNGRTIEFNPETKRLSIRTVHQGEKEI",
    "output": "Deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTQAITVEESRELDDKTINKIGIPSLVLMERAGLKIYENMLDNKDLDLSNVLILAGTGNNGGDGLVVARLLATHGYQVSILTVGNPDHASEDHLAQARICNYYQIPKVFMNADFNKFTTLVDALFGSGLSRNVGGDFATIIDKANASTAKIHAIDIPSGLNGDTGDVMGTAIKAISTSTVAYPKVGMLKDQAKPYTGKIYVDDIGIYRGNAFENE",
    "output": "Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKEKFERTKPHCNIGTIGHVDHGKTTLTAAITKVLSETGGAVFTDYDQIDKAPEEKKRGITISTSHVEYETTKRHYAHIDCPGHEDYVKNMITGAAQMDGAILVVSAVDGPMPQTREHILLSRQVGVPSLVVFLNKVDMVNDPEMLDLVEMEVRELLLSYKYPGDEIPIIRGSALKALQGEIEYKKSILKLMEAVDNYIPQPERSFDRPFLMPVEDVFSIAGRGTVVTGRVEQGQIKIGDAVEIIGLGSTVKTTCTGIEMFHKLLDYGQAGDNLGMLIRGIQRDAVQRGQVICAPGSVKPHTKYEAQVYILTKEEGGRHKPFFNNYRPQFFFRTADVTGTIQLPKDVEMVNPGDNVKLIIELITPIAMEEGIRFAMREGGRTIGAGVVSKIIE",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MHINIAWQDVDTVLLDMDGTLLDLAFDNYFWQKLVPETWGAKNGVTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLDICAMTTEMGPRAVLREDTIPFLEALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAEATGLKAERTLFIDDSEAILDAAAQFGIRYCLGVTNPDSGIAEKQYQRHPSLNDYRRLIPSLM",
    "output": "Catalyzes the dephosphorylation of different purine nucleotides (GMP and IMP)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKPLRLSSLDPVRMPEWRWAPFLSHAINALIPLKPEPYPVAPEFLQREGKTGSKSQPIKVTTCTWACRTKKFRQVRAACVEAGSSASVLNFVINPYHTFDLPFFGADLVTLPSGHLLALDLQPAITSDERHTKQVWERLMPIFEQWRVRLPEGGPIPEEAKPYFSPGFLWTRLHLGSEGNQLIDEVIMPAFRDYLNLYLDLVEMAEEVSPQRAFKLLEGQKRYLSYRGKKDPARAMLARFHGHQWTESYIHNVLFDL",
    "output": "Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEAVSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTTANTDEESRALLTGLGMPFAK",
    "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSERKYFGTDGVRAVAGEFPLTSAWVMSLGAAAGEVLRRVNPHARVVIGKDTRQSGDMLEAALAAGLTSRGVTVIHVGVLPTPGVSYLTRHLKADAGVVISASHNPYEDNGIKFFGADGQKLSDATELQIEAAIDEVPGFAPLTGTAMGSVTNYTEAEHLYTDFLKSHAPDLSGLKIALDCANGAAYRVAPKVFQAAGADVFAIYTTPDGRNINRGCGSTHMDHLRQIVREGEYDLGVAFDGDADRALFVDSRGQVVHGDHMLLLNARARGEQAVVATIMTNMALEAKLQDAGIPLERTAVGDRYVHERLHEKGLSLGGEQSGHVLFLDISPTGDGVLTALLTLASMKKLGTTLDALHDDLVMYPQTLVNVRVQDKKAIAVDQQVQQAVRQAEEQLLGRGRVNLRPSGTENLIRVMVEGQDAAEIHEVARVLAGVVEARGQA",
    "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSQDKKTPLYETHRTLGAKMIPFGGWDMPVQYSGIIAEHNATREAAGLFDVSHMGEIFITGNPKSILLFLESITCNSVASLSDFQVQYNAILNQNGGLVDDVTIYKFSSEKYMICSNASNYEAVTEHLLEHLPISGVKVDNQSLQWHQIALQGPKANEIFSKFLKRDLDSIQYYRFMLLPYQGEEIIVSRTGYTGEDGFEIYSSIPIGLKLWNELLEFGKPYGLLPCGLGARDTLRIEAKYPLYGHELNDQWTPIESGIGWIVKEKENPYFSSEKILFQKKNGVPSKIVSFALTEAGVPRENFRVLDSQGNEIGKTTSGTFSPSLKKGIGLALIQSEKIKDGEPIQIEIREQPKQAIITMKPFIPGSIRKN",
    "output": "The glycine cleavage system catalyzes the degradation of glycine."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "GIPCAESCVYIPCITAALGCSCKNKVCYRN",
    "output": "Probably participates in a plant defense mechanism."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEVPMDCPGCENKVRKALEKMNGVHDVQIDIKQQRVTVTGSAEQKKVLKVARNVTKRDICLWSYPYHPESNGYNDRYFKKKFRKRINMSVNGEKVSSYNYHKHGYHGHEHGYYQERPYSGLINPSASSMFSEENPHFCSIM",
    "output": "Heavy-metal-binding protein."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTRLTLALDVMGGDFGPSVTVPAALQALNANSQLTLLLVGNPDIITPLLAKADFEQRSRLQIIPAQSVVASDARPSQAIRASRGTSMRVALELVKEGRAEACVSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQFAVMGAVLAEEVVGIKNPRVALLNIGEEETKGLDSIREASLMLKTVPTINYIGYLEANELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKSLTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAARLESVYPAGFEPLDDGKGVNLRAHR",
    "output": "Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "STHGKIRIHDYVANGYVILFSHPGDFTPVCTTELAAMANYAKEFEKRGVKLLGISCDDVQSHKEWTKDIEAYKPGSKVTYPIMADPDRSAIKQLNMVDPDEKDAEGQLPSRTLHIVGPDKKVKLSFLYPSCTGRNMDEVVRAVDSLLTAAKHKVATPANWKPGECVVIAPGVSDEEAKKLFPQGFETKDLPSKKGYLRFTKV",
    "output": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (By similarity). Seems to contribute to the inhibition of germination during stress (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDQNGMEIPVTLIIKAPNQKYSDQTISCFLNWTVGKLKTHLSNVYPSKPLTKDQRLVYSGRLLPDHLQLKDILRKQDEYHMVHLVCTSRTPPSSPKSSTNRESHEALASNSNSSSDQSGSSTPSSSQETLTLATSSSSEGLRQRTLPQAQTDPAQSHQVPYVMQGNVDNQLPGQAVPAGFPVYPAFNPLQMLWWQQMYAHQYYMQYQAAVSAQATSNANPAQPAATQPLNLAHVPGEEPPPAPNLVAQENRPMNENVQMNAQGGPVLNEEDFNRDWLDWMYTFSRAAILLSIVYFYSSFSRFIMVMGAMLLVYLHQAGWFPFRQEGVQHQAPNNNAEVNNDVQNANNLELEEMERLMDDGLEDESGEDAGEDASAIQRPGLMASAWSFITTFFTSLIPEGPPQVAN",
    "output": "Could be involved in the unfolded protein response (UPR) pathway."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKVVRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLPAAEEV",
    "output": "Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRKYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVTVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVIGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEIDAINGNEITFKSGKVEHYDMIIEGVGTHPNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK",
    "output": "Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIQYLQVGKIVNTHGIKGEVKAIPLTDNPRRFNKLKWAYVSKEISNEMPKFDIVSVKHHKNFVILKFSGIDDMNAAEKLKEHFVIIDRKDAVKLPKDTFFICDLIGMNVFDTEEKKLGVLTDVLSTGSNDVYVVKSDNNKEILIPALKSVVKKVCFEDNKMVVDLPQGLIDDEV",
    "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLHIDELTFENEVLQSEKLVLVDFWAPWCGPCRMIGPILEEIAKEFNLKVVQVNTDENPNLATFYGIRSIPTLMLFKKGQRVDTVIGAVPKSILIHTINKYL",
    "output": "Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLRRGVKIGVLTNNENKFIELKEIAKNFNIELEHLRGEKIEIQSDDLEEISRTAANLAYLIFRRPLIVDDSGLFVQALQNFPGPYTNFVKNTIGLKGILKLLEGIKDRSAYFMTALTFTDGKIIKTFIGIVKGAISEEIRGNLGFGFDPIFIPEGEKRTFAEMSLEEKNRYSHRARAFAKFAEFLESYTEKE",
    "output": "Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLSSALKLTKKVCSTKSNGLIRSFSTQTQSRDYAVVDHTYDAIVVGAGGAGLRAALGLTEKGYKTACITKLFPTRSHTVAAQGGINAALGNADQDDWRWHAYDTVKGSDFLGDQDAIHYMCKEAVPTVLELEQYGVPFSRMDDGRIYQRAFGGQSKNFGKGGQATRCCAAADRTGHALLHTLYGQAVKHNTKFFIEYFVTDLIMENGDCRGVVAINLEDGTIHRFRSHATVIATGGYGRAYFSATSAHTCTGDGNAMVIRAGLPCQDLEFVQFHPTGIYGSGCLITEGARGEGGYLLNSSGERFMPRYAPSVADLASRDVVSRSETMEIREGRGVGPEKDHCLLNLTHLSPEIIDERLPGIRETAMIFAGVDVTKEPIPVIPTVHYNMGGIPTNYKGQVITQVDGKDKLVKGLYAAGESACVSVHGANRLGANSLLDIVVFGRAVANEIENTLAKDTPHKPLPPNAGEESIANIDAIRFSNGTRSTAEIRLEMQKIMQRNAAVFRDGQVLKEGVELIDKCARSLINDLKTTDRTMIWNTDLIESLELQNLMTQAVLTMHSAEARKESRGAHAREDYKERDDANWMKHTLSYLDVNTGKVTLNYRPVVSETLDQSEMETIKPFKRVY",
    "output": "Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKNIEKSEIIISLVDVDKEFGDKKVLDQINLDIKRGDFVTLLGPSGSGKTTILRLIGGFEWTTRGEIKFNGIDIKDVPAHKRDTATIFQDYALFPHLSVRGNIEFGLKLKRIKKKAEEIPDVVWKKFEHLKKKWQDKQKRKIKELKILQAHLEKLLENPQLDIKKRKKLQDKLDDSDFRYSNWENYLTSKSESFKKKYLTRKITKQEINKEITDIIDLVGLTGNENRAISELSGGMKQRVALARSLVIEPEIVLLDEPLSALDTKIRQKMQVFLKKIQQKLGLTFIFVTHDQDEALQLSDKIAIIRNGKIAQYDEPKQIYDYPVNKWVANFIGDSNFFQAKYIKKNQVEILGLKLYTIHDEFIPGQKLDCLIRPEDIDIDLNSGYFKGKVIQNIYKGSYYSLDIKVENTIINVETNDFYDLETQVFLKWDDDAIHLMEMENAEI",
    "output": "Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTNIRKSHPLAKMINKSFIDLPAPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGMYYGSYTFSETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGVVSDSDKIPFHPYYTIKDILGLLLLILTLMLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAIIPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFITIGQLASIFYFSILLILMPIFSTIENHLLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMPTQRLAEADPQIAKLIREETRRQAEGLELIASENFVSPAVLEALGSTLTNKYAEGYPGKRYYGGCEVVDQVEQLAIDRAKQLFGADHANVQPHAGSQANMAAYFALAKPGDTVLAMSLNFGGHLTHGSPVNFSGKLFKIVPYGLRQSDETIDMDEVARLAREHRPRILMVGASAYSRTLHFDRFAEIANEVGAAMVVDMAHIAGLVAAGLHPSPVPHSEIVTTTTHKTLRGPRGGMILCREAHAKTLNSQIFPGIQGGPLEHVIAAKAVAFGEALRPEFKAYQRRIVENAQVLAEGLKSAGLRLVSGGTDNHLMLVDLRPKKLTGKIAEEALGRAGITVNKNMIPWDPEKPMTTSGIRVGTPALTTRGMGSREMTLVAALIGRVLDAPADEQVLARVRGEVKDLCAHFPMYADRV",
    "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIQKSKIKDLVVFTDENNSKYLNVLNDFLSYNINIIKVFRSIDDTKVMLIDTDYGKLILKVFSPKVKRNERFFKSLLKGDYYERLFEQTQKVRNEGLNTLNDFYLLAERKTLRFVHTYIMIIEYIDGIELCDMPDIDDALKNKIQQSINALHQHGMVSGDPHRGNFIIKNGEVRIIDLSGKRASAQRKAKDRIDLERHYGIKNEIRDLGYYLLVYRKKMRNFMRRLKGKPAR",
    "output": "Catalyzes the phosphorylation of heptose(II) of the outer membrane lipopolysaccharide core."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPSTPSLKVVHELPACTLCVGPLEDAVTAPCGHTFCRLCLPTLSQMGAQSSGKILLCPLCQEEEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSMERDEIEDVKCREDQKLQVLLTQIENKKHQVEAAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVSRLGAQVKELEEKCQQPASELLQDIRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKNLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRYVGVALDYEAGQVTLFNAQTQEPIFTFAASFSGKVFPFFAVWKKGSCLTLKG",
    "output": "E3 ubiquitin ligase that plays a role in several processes including innate antiviral immnity, cell migration and chemotaxis. Acts as a 'Lys-63'-specific ubiquitin ligase for MAPK1/ERK2 and MAPK3/ERK1, promoting their activation by facilitating their interaction with MAP2K1 and MAP2K2. Plays also a role in cell migration and chemotaxis by acting as a stable focal adhesion component upon recruitment by multi-adapter protein paxillin/PXN. Functions in the RIGI-mediated interferon induction pathway upstream or at the level of MAVS. Inhibits NF-kappa-B activation by turnover of 'Lys-63'-linked ubiquitination of MAP3K7/TAK1. Mechanistically, prevents TRIM8 cytoplasmic translocation and thus inhibits TRIM8-mediated 'Lys-63'-linked polyubiquitination of MAP3K7/TAK1 in the cytoplasm. Plays also an important regulatory effect on the activation of hepatic stellate cells (HSCs)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAAERTQNLQDTFLNHVRKSKTPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKHAISTIMPGHPVQLFDPTDEVASEKA",
    "output": "RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Seems to be involved in the regulation of NifA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREGFVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLGIAIISTSEGLLTDKEARQKNVGGEVVAYVW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLEKVKNIIVVLSGKGGVGKSTVSTQLSLALRKNGFKVGLLDIDLCGPSVPYLLGLEGRDIFQCDEGWVPVYTDESQTLAVMSIGFLLKNREDPVIWRGPKKTMMIRQFLTDVRWDELDYLIIDTPPGTSDEHITVMECLKEVGCHGAIIVTTPQEVALDDVRKEITFCKKTGINILGIVENMSGFVCPHCTSCTNIFSSNGGASLANYAQVPHLGTLPIDPRVGVLAGSTTSVLDELPDSTTAEVLTHIVEKLKTIFVS",
    "output": "Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASSSASATVAVDKATSDLLLGPDWTTNMEICDSVNSLHWQAKDVVKAVKKRLQHKSSRVQLLALTLLETLVKNCGDYLHHQVAEKNILGEMVKIVKKKADMQVRDKILVMVDSWQQAFGGPEGKYPQYYWAYDELRRSGVEFPRRSPDASPIITPPVSHPPLRQPQGGYGVPPAGYGVHQAGYGVPQAGYGIPQAGYGVPQAGYGIPQVGYGMPSGSSRRLDEAMATEVEGLSLSSIESMRDVMDLLGDMLQAVDPSDREAVKDEVIVDLVERCRSNQKKLMQMLTSTGDDELLGRGLDLNDSLQILLAKHDAIASGSPLPVQASGSPLSVQASKPADSSPKSSEAKDSSSIAGSSSPIPATVSTGKSPIDEEYEEEEDEFAQLARRHSKPPASVTTDPTSLESHNAASNALALALPDPPPPVNTTKEQDMIDLLSITLCTPSTPPAPSSQPSPPPPAGSDQNTHIYPQPQPRFDSYVAPWAQQQQPQQPQAQQGYSQHQQHQQQQGYSQPQHSQQQQGYSQLQQPQPQQGYSQSQPQAQVQMQPSTRPQNPYEYPPPPWASTSANAYYTPRANASASYTDTSALAGRSLQQSNSFPTRAGDPQATSTASNSGVSVGQKPFVPSYRLFEDLDVFGSADGKHNKPANSSNGSQNLSGSQTQQSMIGGRKMI",
    "output": "Acts as a gatekeeper for degradative protein sorting to the vacuole. Plays a role in recognition of ubiquitinated PIN2 auxin carrier at the plasma membrane and further to its endocytic sorting. Binds ubiquitin in vitro . Might contribute to the loading of the ESCRT machinery (Probable)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSNPQFRAGFVAIVGRPNVGKSTLTNALIGTKISIVSRKAQTTRHRIHGVLTREHEQFVFVDTPGFQTRHGGAMNRMMNRVVTQALADVDVVVHVVEAGKWSEGDAKLLPLLPKSRRSILVVSKIDALKNRDELFPFVSKLMALHAYDAVVPVSATKGQQLDQLLDEIAAGLPQGDPMFEEDTLTDRPVRFIAAELVREKIFRLVGDELPYGCTVVIEQWEETERGVRIAACVVVERESHRPILLGAGGMHMKRIATEARQDIAKLLDMPVHLEIYIKVRKGWSDREGALRDLGYE",
    "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTWQAYVDNNLLGAGFASAALLGAADGSVWAHSAGFNVAEGKAITALFQKDGAAFATGIHVAGKKYMAIKSDTRSAYGKLGAGGVVCVKTLTCIIVAVYDDKLQPGAAANIAEKLADYLIDNNC",
    "output": "Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTDTVVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMETMEQERIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETSNNRPHPVWLCKICLEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPAGEPATQEQPTPESRHPARAPARGDMEDRRAPGQKPGPDLTSAPGRGSHGPPTRRASEARMSTTTRDSEGWDHGHGGGAGDTSRSPGGEQGLRRANSVQASRPAPASMPSPAPPQPVQPGPPGGSRAAPGPGRFPEQSTEAPPSDPGYPGAVAPAREERTGPTGGFQAAPHTAGPYSQAAPARQPPPAEEEEEEANSYDSDQATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD",
    "output": "Plays an essential role in docking and fusion steps of regulated exocytosis . At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP-dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release . In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability . Also plays a role in the exocytosis of arginine vasopressin hormone ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKLLRRAWRRRAALGLGTLALCGAALLYLARCAAEPGDPRAMSGRSPPPPAPARAAAFLAVLVASAPRAAERRSVIRSTWLARRGAPGDVWARFAVGTAGLGAEERRALEREQARHGDLLLLPALRDAYENLTAKVLAMLAWLDEHVAFEFVLKADDDSFARLDALLAELRAREPARRRRLYWGFFSGRGRVKPGGRWREAAWQLCDYYLPYALGGGYVLSADLVHYLRLSRDYLRAWHSEDVSLGAWLAPVDVQREHDPRFDTEYRSRGCSNQYLVTHKQSLEDMLEKHATLAREGRLCKREVQLRLSYVYDWSAPPSQCCQRREGIP",
    "output": "Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate. Has no activity towards substrates with terminal glucosamine or galactosamine residues."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRPTGRSAQQVRPLKLTRHYTKHAEGSVLVEFGDTKVLCNATVEEGVPRFLKGQGQGWVTAEYGMLPRATHSRNAREAAKGKQGGRTLEIQRLIARSLRAAIDLKVLGEYTITLDCDVLQADGGTRTASITGACVALADALNQMVANGKLKKNPMKGMVAAVSVGIVNGEALCDLEYVEDSAAETDMNVVMTEDGRMIEVQGTAEGEPFSHEELLSLLALARGGIETIVQAQKAALID",
    "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDLLKIKDPSFMKQLDIKELEALAADIRAFLITSTSKSGGHIGPNLGVVELTIALHYTFNSPKDKFIWDVGHQSYVHKILTGRANQFDTLRKHGGLDGFPKRKESIHDVFETGHSSTSLSAACGMVIARDIKKEDFYVIPIIGDGALTGGMAFEALNHIGDMGKDMIVILNDNDMSIAPNVGALHNVLGKLRTSDKFQQTKTNIDKLIRKIPTAGEKLADTAEKTKDSLKHLLVNGTFFEELGFMYLGPIDGHNLEDILTNLEIAKRARGPVILHVVTKKGKGYQPAELDSRGTWHGTGPYKVETGSFIKSVKTAPSWSSVISNELMRLATADERIVAITPAMPVGSKLEKFAKAFPERFFDVGIAEQHATTMAAGLATQGMKPFLAIYSTFLQRAYDQLVHDVCRQKLNVVIGIDRAGLVGADGETHQGIFDISFLNSIPNMIITMPKDEVEARQLMVTAFDYDAGPFAIRYPRGNGLGVELTESNTLIPIGEWETIIQPIDAVIVTFGPTIQLALKAADQLETEGYRVGVINARFIKPLDETLLHQMIKQKIPILTVEESLLKGGFGASVLEFIETNNYTDVAIHRIGLPDEFISHGSVPVILESYGISEAGIELKIKEMLAQSEKLRAKRL",
    "output": "Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSLASLSVSPGKGRRVVVGMSGGVDSSVTAWLLKQQGYEVIGLFMKNWEDDDDSEYCSTRQDLLDAASVADLVGVDFEYVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMTLGAEHIATGHYARVRAIAGAHGREYQLLKALDGSKDQSYFLHRLNQAQLSRTLFPLGEIHKTEVRRIAHDIGLHNAAKKDSTGICFIGERPFREFLNRYLPTEPGDILTPQGQRVGRHHGLSFYTLGQRKGLGVGGVKGSQRDDGTADAWYVARKDLQHNILYVVQGHDHPWLLSNRLQALDASWVAGRAPELRGYGAKTRYRQADAACVLEQASQGAFELSFSQPQWAVTPGQSAVLYDGDVCLGGGIIA",
    "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNINVDVKQNENDIQVNIAGEIDVYSAPVLREKLVPLAEQGADLRICLKDVSYMDSTGLGVFVGTFKMVKKQGGSLKLENLSERLIRLFDITGLKDIIDISAKSEGGVQ",
    "output": "Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEESKTPHVAIIPSPGMGHLIPLVEFAKRLVHLHGLTVTFVIAGEGPPSKAQRTVLDSLPSSISSVFLPPVDLTDLSSSTRIESRISLTVTRSNPELRKVFDSFVEGGRLPTALVVDLFGTDAFDVAVEFHVPPYIFYPTTANVLSFFLHLPKLDETVSCEFRELTEPLMLPGCVPVAGKDFLDPAQDRKDDAYKWLLHNTKRYKEAEGILVNTFFELEPNAIKALQEPGLDKPPVYPVGPLVNIGKQEAKQTEESECLKWLDNQPLGSVLYVSFGSGGTLTCEQLNELALGLADSEQRFLWVIRSPSGIANSSYFDSHSQTDPLTFLPPGFLERTKKRGFVIPFWAPQAQVLAHPSTGGFLTHCGWNSTLESVVSGIPLIAWPLYAEQKMNAVLLSEDIRAALRPRAGDDGLVRREEVARVVKGLMEGEEGKGVRNKMKELKEAACRVLKDDGTSTKALSLVALKWKAHKKELEQNGNH",
    "output": "Bifunctional O-glycosyltransferase and N-glycosyltransferase that can detoxify xenobiotics. Possesses high activity to metabolize the persistent pollutants 2,4,5-trichlorophenol (TCP) and 3,4-dichloroaniline (DCA). Also active on benzoates and benzoate derivatives in vitro."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKSALLFTLVVAAVHAQSPQVISPAPRRESNEIDCPEYCLDVYDPVGDGEGNTYSNECYMKRAKCHNETTPPAWKDLVLITGSSTGEQPPSKKCSTVCPDVELPVCGSNRVRYGNPCELRIAACEHPELNIVEDSGKACVGSKVTPQEG",
    "output": "Secreted effector that interacts with and inhibits the pathogenesis-related P69B subtilisin-like serine protease of host tomato . Inhibition of host proteases by a pathogen extracellular protease inhibitor forms a specific type of defense-counterdefense mechanism between plants and microbial pathogens ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARDKNKENDGSWKKFLWDPEKKEFMGRTGSSWFKILLFYLVFYGCLAGIFIGTIQVLLLTLSIYEPKYQDRVAPPGLTQVPRAVKAEISFTVGNPSTYEDYVTSLSNFLNQYNSSKQDNLALFEDCGDKPKGYIDRGAISPDHGTKRSCQFKREWLGECSGLNDTTFGFNEGKPCLIVKLNRIVGFKPRPTNVDVPAAVANLTENIIPLHCKGKRPEDDNNLLDIQYYGMGGYPGFPLNYYPYYGRLLQPNYLQPLIAVQFTNITLDTEVRIECRAYGENLLLSEKDRFQGRFDIKIEMKSS",
    "output": "This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of this glycoprotein is not known. Some specific sequence of the beta subunit can modulate the activation of the Na,K-pump by extracellular potassium ions."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIASVRGEVLEIALDHAVIESAGVGYRVNATPATLGGLQRGTEARLVTAMIVREDSMTLYGFPDSESKELFGLLQTVSGVGPRLAMATLAVLEPEALRSALAEGNVTALTRVPGIGKRGAERMVVELRDKVDAVGSTSGAVPLGAGGGGSVRDQIVEALVGLGFPAKQAEQATDSVLAEAPESTTSSALRSALSLLGKTR",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPHVEAITLTRDRRGPGLGAVRLWLYAVAALIIAMVVVGGATRLTESGLSITEWKPVTGALPPLSQADWQAEFDKYQAIPQYEILNKGMGLEAFKRIYWWEWGHRLLGRLIGFAFLLPFLWFAWRGVLRGRLLAKCLVLFLLGGLQGAVGWWMVASGLTARVSVSQYRLAIHLTLACIILSAIVAVARSLSPEPRQVVGGRLRATAWALVALVLVQIFAGGLVAGLDAGMAFNTWPLMDGHLIPPAAQLAAADPFWRNLFENALTVQFNHRMIAYALWTLTLLHALDARRAGGAVAQRAWVLFALVTAQASLGILTLIHQVPIDLALAHQFGATLVLVVATLHLGGLSGQVEPATPKLRLVKG",
    "output": "Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKPVKIGPWGGNGGSERDVQPKPIRMVSMTVSSGAIVDAIAFTYVGTDNVQHSSGIKWGGTGGTEDTINLDATNYVTEISGTVGKFGTDDIVTSLKIITSKGVTRTYGSGTGIPFRVPVLDGGKIAGFFGRAGAFLDAIGFYITP",
    "output": "Mannose-specific lectin. Has a weak agglutinating activity against rabbit erythrocytes (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNIEALKVFKESGEKITCLTAYDASFASVFDACGIDIILVGDSLGNVIQGDKNTLDVSMSDMIYHMQAVAKGTQNALRIADMPYQSYTYAEQTLTNAKRLIMAGAQMVKLEGGCEHEASFRILQGNDISVCGHLGLQPQSVVEIDGYRVQGRGKQGANKIIKNALALASWGVKVIVLECVPAELAKQVSQSVSIPIIGIGAGLDCDGQVLVSYDMLGVHVRHVPRFVKNFLTDNGDVKSAVNAFIKAVKDKSFPSKKYSY",
    "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRRIGAHVSIAGGIENAPMRAREIGATAFAMFTKNQRQWNAPPLTTQSIDAFKNNCAECGYHARHILPHDSYLINLGSPDPAKLERSRKAFTDEMQRVEALGLSLLNFHPGSHLNETGIDNCLNTIAESVNIALDNSSGVTAVLENTAGQGSNLGHTFEQLAAIIDQIEDKTRVGVCLDTCHLFAAGYDLRTSEAVEATFNEFDSIVSLSYLRGMHLNDAKLDLGSKRDRHESIGSGFIGNDGFAAIIQHPACDEIPLILETPNPDIWNREIEMLYQMEGDKR",
    "output": "Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKEKFERVKPHVNVGTIGHVDHGKTTLTAAICTTLAKVYGGAARDFASIDNAPEERERGITISTSHVEYDTPARHYAHVDCPGHADYVKNMITGAAQMDGGILVVAATDGPMPQTREHILLGRQVGIPYIIVFMNKCDMVDDEELLELVEMEVRELLSEYDFPGDDLPVIQGSALGALNGEEQWEAKIIELAEALDTYIPEPERAIDLPFLMPIEDVFSIQGRGTVVTGRIERGILKVGDEVAIVGIKDTTTTTCTGVEMFRKLLDEGRAGENVGALLRGTKRDEVERGQVLAKPGSITPHTKFESEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGDISLPEGVEMVMPGDNIQMVVELISPIAMDEGLRFAIREGGRTVGAGVVAKIFA",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMSYYMDTTIGSTGPYPLARPGVMQGASSCCEDPWMPCRLQSACCPPRSCCPPWDEAAIQEVPTGLEHYSTDMECADVPLLTPSSKEMMSQALKATFSGFAKEQQRLGIPKDPQQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKECFLELAPDFVGDILWEHLEILQKEEAKPYPANGVNAAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPVQTDSLQTDYFTIKQEVVTPDNMCMGRASRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFQSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADMNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE",
    "output": "Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MARNIKVEELLQTPIEKQQIELVERKGIGHPDSISDGLAEAVSRALCREYITKCGAVLHHNTDETQIVAGRSSPKFGGGEVLQPIYMLLVGRATKEFEGAELATESVALKAARNYLRNTMVNMDLERDVIIDCKLGTGSSDLRDVFKRDRVPMANDTSFGVGHAPFSELENIVYNTERQLLTDLKSRMPAIGEDMKIMGLRDGDDISLTICSGMIGRYVDDLDSYINMTQEMKTYTEELAARYTERNVNVFVNTADNLKASCVFLTVTGTSAEMGDDGSVGRGNRCNGLITPNRPMSMEATSGKNPINHIGKIYNLLSTQMARDIVKQVPDVQDVYIRLLSQIGKPIDQPLVASAQIIPKEGTSFANVKSEAEVVIDDWLSNVTKITEMVIRGELNTF",
    "output": "Catalyzes the formation of S-adenosylmethionine from methionine and ATP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MITELAAMLKERFGIVFNDPDLLAEAFTQASYVNEHQDQQLKYYERVEFLGDAVLELVVSEYLYKRYKDMPQGKLTRLRAAMVCEESFASFARECDFPQYIRLGKGEQKAHAWERDSLLCDIFESFVGALYLDQGREPVLKFVHQVIFPKLDEGRFDGVFDYKTTLQEYLQRDGDVAIDYQLIEQDGPANERSYEIAVLADGQKIGEGWGHSKKEAEQSAARQAYSQLQQK",
    "output": "Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQSPDGQETGRPAAILIAGPTASGKSALGLRIARAFGGTVINTDSMQVYADLRVLSARPTAEEEGLAPHRLYGSIDGAVNFSVGHFQRQAAALLSEMDAGSLPVFVGGTGLYFRSLDEGISDLPEVPDAVRQRIRIEADGQPTETLHAALALRDPESAERLRPSDRMRVMRALEIHAATGRSIGSFHEARVPGPLAGKPLLKLFLATEREALRQRIDARFVTMMEQGALDEVAALRERRLDPLLPVMRAHGVPGLIAHLDGTISRQEAIQRGQGDTRRYAKRQFTWFRHQMGEAWHWTTPEAAWSLVQARLSAPAGR",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPHYRRILLKLSGEALLGDGQYGIAANTLDRIADELAEINAMGVEVAVVIGGGNIFRGAGLAASGMDRVTADHMGMLATVMNALAIQDALERRSVFCRVMSAIKINQVCEDYIRRRAVRHLEKGRVVIFAAGTGNPFFTTDSAASLRAVEVGAELLLKGTKVDGVYSSDPVRDPEAKRYQQLTYDEVLSKRLEVMDATAIVLCRDQAMRIMVFDITSPGTMVAAARGEPVGTVVDPGLPSAQEESS",
    "output": "Catalyzes the reversible phosphorylation of UMP to UDP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLAGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLDVTTSHSPAAPGEQGFGECLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRGLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKPHVTEAFQFHF",
    "output": "Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAIISSNIGDNDFSLRKKELRLVDSKIIPEEKRKNNLNLARPITFQEFIGQEKLKSSLRIAIDASIYRKEPLEHTLLYGQPGLGKTTLAFLIAKEMNTKCRIATAPAIERPRDIVGLLLGLKEGEVLFIDEIHRLNRLTEELLYSAMEDFRLDLTMGANRGARCRTINLPRFTLVGATTKLASISAPLRDRFGISQKIEFYTCDELKQIIDNFSRLISFNVDDEASSHLAKISRGTPRIALRLLRRVRDYAQVVKKTNVISVNLIKKALNSYQIDEKGLDYVDRQYLSFLNQNKNIPTGLDSIAAGLGDDSSMLEFVVEPYLIQIGFLTRTPRGRLLTALGKKYIDSKNDNF",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNIEQIFKKPLKRNINGVVKAEQTDDASAYIELDEYVITRELENHLRHFFESYVPATGPERIRMENKIGVWVSGFFGSGKSHFIKILSYLLSNRKVTHNGTERNAYSFFEEKIKDALFLADINKAVHYPTEVILFNIDSRANVDDKEDAILKVFLKVFNERIGYCADFPHIAHLERELDKRGQYETFKAAFADINGSRWEDERDAYYFISDDMAQALSQATQQSLEASRQWVEQLDKNFPLDINNFCQWVKEWLDDNGKNILFMVDEVGQFIGKNTQMMLKLQTITENLGVICGGRAWVIVTSQADINAAIGGMSSRDGQDFSKIQGRFSTRLQLSSSNTSEVIQKRLLVKTDEAKAALAKVWQEKGDILRNQLAFDTTTTTALRPFTSEEEFVDNYPFVPWHYQILQKVFESIRTKGAAGKQLAMGERSQLEAFQTAAQQISAQGLDSLVPFWRFYAAIESFLEPAVSRTITQACQNGILDEFDGNLLKTLFLIRYVETLKSTLDNLVTLSIDRIDADKVELRRRVEKSLNTLERLMLIARVEDKYVFLTNEEKEIENEIRNVDVDFSAINKKLASIIFDDILKSRKYRYPANKQDFDISRFLNGHPLDGAVLNDLVVKILTPKDPTYSFYNSDATCRPYTSEGDGCILIRLPEEGRTWSDIDLVVQTEKFLKDNAGQRPEQATLLSEKARENSNREKLLRVQLESLLAEADVWAIGERLPKKSSTPSNIVDEACRYVIENTFGKLKMLRPFNGDISREIHALLTVENDTELDLGNLEESNPDAMREVETWISMNIEYNKPVYLRDILNHFARRPYGWPEDEVKLLVARLACKGKFSFSQQNNNVERKQAWELFNNSRRHSELRLHKVRRHDEAQVRKAAQTMADIAQQPFNEREEPALVEHIRQVFEEWKQELNVFRAKAEGGNNPGKNEIESGLRLLNAILNEKEDFALIEKVSSLKDELLDFSEDREDLVDFYRKQFATWQKLGAALNGSFKSNRSALEKDAAAVKALGELESIWQMPEPYKHLNRITLLIEQVQNVNHQLVEQHRQHALERIDARIEESRQRLLEAHATSELQNSVLLPMQKARKRAEVSQSIPEILAEQQETKALQMDADKKINLWIDELRKKQEAQLRAANEAKRAAESEQTYVVVEKPVIQPVPKKTHLVNVASEMRNATGGEVLETTEQVEKALDTLRTTLLAAIKAGDRIRLQ",
    "output": "BREX systems (bacteriophage exclusion) provide immunity against bacteriophage. Part of a type 1 BREX system which protects against dsDNA phage. This system allows phage adsorption but prevents phage DNA replication, without degradation of the phage DNA. Methylation of bacterial DNA by PglX guides self/non-self discrimination. When the brxA-brxB-brxC-pglX-pglZ-brxL genes are transformed into a susceptible E.coli strain (BW25113) they confer very high resistance to infection by bacteriophage VR7 and VpaE1, about 100-fold protection against lambda, T5 and T7 and no protection against RNA phage Qbeta, ssDNA phage M13 or dSDNA phage T4 and VR5. Glycosylated phage DNA is not susceptible to BREX. The BREX system does not confer resistance to lysogenic lambda phage, i.e. prophage that are integrated into the chromosomal DNA and then induced to form phage."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTDASHPTAADDLGALSTLFRSEQGGHERVLLCQDRESGLKAVIALHSTALGPALGGTRFHAYASDEEAVLDALNLARGMSYKNALAGLPHGGGKAVIIGSPAPVSEGGLKSEALLRAYGRFVASLDGRYVTACDVGTYVADMDVVARECRWTTGRSPENGGAGDSSVLTAFGVFQGMRASAQALWGEPTLRGRTVGVAGVGKVGHHLVDHLVEDGARVVVTDVRPESVERVRARHPRVVAVPDTESLIRADLDVYAPCALGGALNDDTVPALTARVVCGAANNQLAHPGVEKDLAGRGILYAPDYVVNAGGVIQVADELLGFDFDRAKAKAAQIFDTTLAIFDRARTDGVPPAVAADRIAEQRMAEARTV",
    "output": "Oxidative deamination of branched-chain amino acids. The catabolism of valine is the major source of fatty acid precursors for macrolide biosynthesis and a vital source of antibiotic precursors."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKFVDEAFVRVEAGNGGHGCLSFRREKFIPRGGPDGGDGGDGGSVYFVADKSVNTLVEFRYQRLLRAQNGQPGMGRLRSGKKGEDLIVPVPLGTTVYDKETSELIGDLIEAGDKLCVARGGRHGLGNTHFKSSTNRAPRRTTSGEEGEARELKLELKLLADVGLLGLPNAGKSTFIHAVSKATPKIADYPFTTLYPHLGVVRVEEYRSFVIADIPGLIEGASEGAGLGVQFLKHLERTQLLLHIVDIAPLDGSDPVQSIQAIISELEQFSQNLSQKPRWLVFNKIDLLAPDVAQARCQEIINRLNWKGPVYKISAIKRQGTELLCYDLMSFLETNQRSI",
    "output": "An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ",
    "output": "Involved in the binding of tRNA to the ribosomes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKIGSHVSLSGKKMLLGASEEAASYGATTMMVYTGAPQNTRRKPISDLRIPEALLHMEENGIEEIVVHAPYIINLGNTTKPETFELAVSFLGEEIRRAEALEKAKHIVLHPGAHVGAGEEVGIKRIIEGLNEVLTGDEKVKIALETMAGKGSEIGKTFEEIAAIIAGVTHNDRLSVCLDTCHVHDAGYDLIHDLDGVLESFDRIVGINRLGVIHVNDSKNIRGAKKDRHENIGFGEIGFDPLHRIVHHRDLAHLPKILETPYIGLDPRKKVAPYREEIAMLRSGNFDAEWRLPLIGTSI",
    "output": "Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS",
    "output": "Functions as a stress-inducible and DNA-binding transcription factor that plays a central role in the transcriptional activation of the heat shock response (HSR), leading to the expression of a large class of molecular chaperones, heat shock proteins (HSPs), that protect cells from cellular insult damage. In unstressed cells, is present in a HSP90-containing multichaperone complex that maintains it in a non-DNA-binding inactivated monomeric form. Upon exposure to heat and other stress stimuli, undergoes homotrimerization and activates HSP gene transcription through binding to site-specific heat shock elements (HSEs) present in the promoter regions of HSP genes. Upon heat shock stress, forms a chromatin-associated complex with TTC5/STRAP and p300/EP300 to stimulate HSR transcription, therefore increasing cell survival. Activation is reversible, and during the attenuation and recovery phase period of the HSR, returns to its unactivated form. Binds to inverted 5'-NGAAN-3' pentamer DNA sequences. Binds to chromatin at heat shock gene promoters. Activates transcription of transcription factor FOXR1 which in turn activates transcription of the heat shock chaperones HSPA1A and HSPA6 and the antioxidant NADPH-dependent reductase DHRS2. Also serves several other functions independently of its transcriptional activity. Involved in the repression of Ras-induced transcriptional activation of the c-fos gene in heat-stressed cells. Positively regulates pre-mRNA 3'-end processing and polyadenylation of HSP70 mRNA upon heat-stressed cells in a symplekin (SYMPK)-dependent manner. Plays a role in nuclear export of stress-induced HSP70 mRNA. Plays a role in the regulation of mitotic progression. Also plays a role as a negative regulator of non-homologous end joining (NHEJ) repair activity in a DNA damage-dependent manner. Involved in stress-induced cancer cell proliferation in a IER5-dependent manner."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPRSLKKGPFIDLHLLKKVEKAVESGDKKPIR",
    "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSDVAVAETPAVKTPTKAPKANATKVPKVKTAAAHPPFINMVTAAISSLKERKGSSKIAILKYITANYKLGDQVKKINSNLRSALKKGVASKALVQTVGTGATGRFRVAEKTAATAKKPTVKKAATGEKVKKTVVKKTVAKKTGDKVKKAKSPKKIAKPAAKKATKSPSKKVAPKKAAAKPAKKTAALKA",
    "output": "Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKLIHDVQEMQQTVLGLKRQGKRIAFVPTMGFLHEGHASLMREGRTRGDVLVLSIFVNPTQFGINEDLASYPRNLEGDCALAESCGVDLVFAPTAAGMYPPGFQTTVALGPLTKPLCGASRPGHFDGVAVVVTKLFGIVQPDCALFGKKDFQQLAIIRQMTLDLNLPVEIIGMPIVREPDGLAMSSRNSYLSVEQRQQALCLHRAILKVRELFKGGETSVDRLLGEARMIITAVPEASVDYLELRDSTTLEPVATAAADSLFALAVKIGSTRLIDNTVLGDTP",
    "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRSKNDTILKAIKGESTSHTPVWFMRQAGRSQPEYRKLKEKYSLFEITHQPELCAYVTHLPVDNYQTDAAVLYKDIMTPLKPIGVDVEIKSGIGPVISNPIQTVKDVERLSQIDPKRDVPYVLDTIKLLTEEKLNVPLIGFTGAPFTLASYMIEGGPSKNYNFTKAMMYRDEETWFALMNHLVDISIDYVVAQVEAGAEIIQIFDSWVGALNVKDYRYYIKPAMNKLISGIKAYYDVPIILFGVGASHLINEWNDLPIDVLGLDWRTTIKQADKMGVNKAIQGNLDPSVLLAPWDVIESRLKDILNQGLNRGKHIFNLGHGVFPEVKPETLRKVTEFVHNYTAK",
    "output": "Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTTNDLFSIYAFSNMYDIFPRKYSQKELEEYHRKNPLFFSYTIFPVIKHRWSKAYICFQNNVYMLNIELDTSKPYDRVPIQHLIDIRPISTDIKKEIYKISDKTFITFECYSYLKCKGYNSIYDITLDDKRGLLSAGNILSIFSSNKQMPEKSSIGILKNPKPFTVIKFKSLSLITQLQIFELLRKRKQIVVTGSTGIGKTSQLPKVIMWYNYLFGGWDNLDRVRFDYISRPIVLSLPRVALVKSNGINFLQSLGFSDFEGSPVELRYGGKTEHTTRQHDGIVLSTNKLTSYSLSNYNIIIVDEIHEHDRIADIIISVLRKNIDTIHSLVLMSATLEDDRDRLQEFLPDVEFYHIEGPVLYSIKEIYVKNKYSYDSKAYTEEEKKNISTTLNWCRPRNGMCGILFLASVSQCISYKKYLEKSNSDMDFIIIHGKIPDITEVLNAVQRPGRERPCILVSTPYLESSITIRTATHVYDTGRVYVPKPFGGDQLFISKSMMTQRKGRVGRVSKGIYVYFYDMCLLKPIKSIDHEFLYEYIVYAKKFKLSLPNDLLVIPSDKDMLKKSEEYIKSFNISFDRLFEIYVNYFVNMVEYVKIYNKGGKKAENLDMFERNDILTGETLKDIKNLQLLVKINTTTRRKKMYCYKGEILFGPYMNTVIRLSSKQLYRNYVYMLTERSFTLYR",
    "output": "NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRGELNIPALSRFGKSISASLHHQNGSSRDDNDSNPYENRSSNSGLNRRNSVFGLPSSGLSSRLSKPSLSSINNSNNSSSNTGGNVLPNPALTPVRNMSNKPPLTWSPSSANLFGTSKVTSIIGNNVSDVVPPVIKKALASSHGGGMSLSIVLLEPVLYLAGFDLNECQIENPALLRGALVLRVAKPANIRGISLSFTGRSRTEWPEGIPVKGHDTYEDKVIISHNWKFYEPTMKDADAPQHGADVARLVGEQLPLPSSAAASLRGYSVFAPGEYTYNFDLAIPNCFPESVEAKMGWVRYFLEATVERFGTFKSNLNGRTPVQLVRTPSPASLSSSELINISRDWDERLHYELQVSGKSFRLGEVVPITFRFLLLDKVRLYKLSISVVESSEYWCRSRKFHRVDPKRRVLLAERSAKHQNTDNLFETPDEGDGLSSAVFNFNVALPTCLVKERDRLTFDTTYKYIKVRHRLKALLVLSIENTENPEKRKYFEINIETPVRILSCRCVKDSTLLPPYESSSQGDNQVLLPCPCRLATTHVEPTEVTAFTTQSVLASSAPSAGRPAAAQISRPAQLFRIPSTNPPPFDGDVCPPACNTPPPNYDELFDVLSSISIQDCETDRANDDTILNNRVRRSGTIREEAPHRSLSRTVSRSFEIPR",
    "output": "May regulate endocytosis in response to extracellular stimuli."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAEENQTPATATEEQQAVLQIQRIYVKDISFEAPNLPHVFQQEWKPKLNFDLSTEAKQLGEDLYEVVLNISVETTLEDSGDLAFLCEVKQAGVFTISGLEDMQMAHCLTSQCPNMLFPYARELVSNLVNRGTFPALNLSPVNFDALFMEFLQRQEQESQNAESSTEVQH",
    "output": "One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFRYEAKVFKELVDSVSKILDEGLFIITGEGLRLRGMDPARVALVDIEIPSSSFFDFYMAGDVERVELGVNMETLKGVVARAKKGDQLEVRVREDKVLFIVESVVLRRYLLPNLEVIVDVPEDISLEFDATATVIADVVKKTLRDVELVGDIVEFDAGEDYLSIRSVGPERRRVETRLTRESPALIDLEVKEPATSRYDVGYLKRMLGVAKIAESIELSFSTDKPLKMVFKSPDGSRVTYLLAPSTG",
    "output": "Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MHDTEFETRAAELIEAGRFIDGRGWVPATSGNFSARLGDGRIAITVSGRHKGRLRPEDIMLVDAAGRSLDGRKPSAETLLHTGIYRRYPEAHAVLHPHSPASTLLSRLVSGAVILEDYELLKALAGIDTHATRIVVPVFPNDQDIPRLALKIEEYLVRHDGVHAYIIAGHGFYTWGKSVADALRHVEALEYLFDLETRMHGVKR",
    "output": "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTDLTEKNTALEEEKIESAVENQQKSIWKEIFAQGIWKNNPAVVQLLGLCPLLAVSSTATNALGLGLATMLVLTCTNTVISLFRQYIPKEIRIPIYVMIIATTVTAVQLLMNAYTYTLYQSLGIFIPLIVTNCIIIGRAEAFASKNSLLHSIWDGFSMGLGMALSLTILGALREIIGQGTIFEGIENLFGEQAKFLTHHIYHTDSSFLLFILPPGAFIGLGLLLAIKNRIDNVKK",
    "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPIGVPKVPFRSPGEEDASWVDVYNRLYRERLLFLGQEVDSEISNQLIGLMVYLSIEDETKDLYLFINSPGGWVIPGVAIYDTMQFVRPDVHTICMGLAASMGSFILVGGEITKRLAFPHARVMIHQPASSFYEAQTGEFVLEAEELLKLRETLTRVYVQRTGKPLWVVSEDMERDVFMSATEAQAYGIVDLVAVE",
    "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQVRTPAIICAMRAHGEHGAIVRALTPDHGLLAGYVRGGRSRRLRPVLVAGNLVEAEFRARTAEQLPGLTVELSHSRAGLLAEPLAAAAIDWLSSLTAASLAEGQPHARLYEALDAVLAAIEYAPSARGWAAAAVRYELMLMADLGYALDLSACAATGARDDLAYVSPKSGGAVSRAAGEPYAARLLPLPAFLVDPSADSDWSDIVDGMRLTGHFLARDILVDRRADALDARQRLVDRIGRLA",
    "output": "Involved in DNA repair and RecF pathway recombination."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MARFRGSITKVSRRLGIALAPKAEKYLERRPFPPGQHGQGRKGKISEYALQLREKQKMKYLYGILEKQFRNYYKKAVAQRGVTGDNLVKLLERRLDNIVFRAGFSPSRAGARQLVSHGHVTVNGKKVDIPSYLVSPADVMEFRQKSKNMSAVTDSLNKTPESRIPAWIQVDKAHQKAVFLSVPERADIQEEFNEQLVVELYSK",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNSGIDLEMSFTQGVQNLGLSHELAHLLWIPLPMLLVLVSAVIGVLVTVWLERKISAAAQQRIGPEYAGALGILQPMADGLKLLVKEDIIPARADSVLFTVGPILVLVPVILSWLIVPFGQNLLISNVGIGIFLWIALSSIQPIGLLMSGYSSNNKYSLLGGLRAAAQSISYEIPLALAVLAIVMMSNSLSTVDIVEQQNTAGLLSWNIWRQPVGFIIFWICALAECERLPFDLPEAEEELVAGYQTEYSGMKFALFYLAGYINLVLSALLVSVLYLGGWGFPISIDWFSSLIGLSIDNPLVQIIAASLGIVMTILKAYLLVFLAILLRWTTPRVRIDQLLDLGWKFLLPISLVNLLVTASLKLAFPITFGG",
    "output": "NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MASVNVDFEQAGELKIGQVGIANLRVRTLDVPRLVQEMRERVSRAPKLFGRAAVILDFGGLSQVPDLATAKALLDGLRDAGVLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYEPTAVSPPPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAENCDLTVLSTVGAGAEVIADGSIHIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGHYKVLDDVPMDLRGKAVQVWLEQDQIKIAALD",
    "output": "Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSWIEKILPKAKTTQKSSIPEGVWSKCSSCNAVLYKAELERQISVCPKCDHHMRISARKRIDSFLDHDNRMELGEEFEAQDILKFKDSKRYKDRLSAAQKNTGEKDALVVMKGELHGMPVVVAAFEFAFLGGSMASVVGARFVKGVEYCLEHNLPFICFSASGGARMQEALFSLMQMAKTSAALAKMSEKGLPYVSVLTDPTMGGVSASLAMLGDINVAEPKALIGFAGPRVIEQTVREKLPEGFQRSEFLLEKGAIDMIIDRREMKITLARMLGKFMGQTSVVS",
    "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFDFQHQLKILPDKPGVYIMKNSLGEVIYVGKAKVLKNRVRQYFQNSKNHSEKVRAMVKNIAEFEYIVTDSEMEALILECNLIKKYSPRYNIALKDDKFYPFIKITTNEDFPRVYVTRNFAKDGNRYFGPYTNGTAVYEVMGLIKKLFPLRTCKKAIVEGGEPTRACLNYHINLCKAPCAGYISKAEYWEMIDEIINILNGTDTSIIKKLKLEMEKAAEELEFEKAAKIRDRILAIELISEKQKMFTVKEGDEDFIDLYTDEKDGCAQVFFVREGKVTGREHFMIENIGDDPVKEVISSFIASFYGGTAQIPKTIYVPEEIEDQELIEKFLTEKRGSKVWIKVPKKGDKKNLLDMVRNNAKIMLDQFKEKMVEEKELNKSALTELADVLGLDSLPVRIEAYDISNIQGVDSVGTMVVFENGKAKNSDYRRFKIKSVKGPNDYESMREILSRRFSHGLEEVNKIKERNLEYSNGKFCIFPDLIMMDGGKGQVNIALEVLKGFGIEIPVCGLVKDHKHRTRGIILNNEEILIRRGSGLMNLITRVQDEVHRYAITYHRSLRDKRTLHSILEDIPRIGEKRRRNLLMKFGSIDNIKKASMEELLDTPGIDKRAAESIKQYFSS",
    "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKPYQRQFIEFALNKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDKDLPYCFNRKEAKDHGEGGSLVGSALQGRVMLVDDVITAGTAIRESMEIIQAHGATLAGVLISLDRQERGRGEISAIQEVERDYGCKVISIITLKDLIAYLEEKPDMAEHLAAVRAYREEFGV",
    "output": "Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLKPSDTWSWYYDNKAQSLMLDLGMDMVFCVNLSPKVLINSAFDDCKFSVDDASAYQMFVEHISYLPLSEPRKVELALNCVAARRFHKPMLPKSWFFETQGAGYYPEEGEIVSLKNDLGEGHFIIVENYECASMCMLVDMDAFALNPTKYMAFCEPIKVMNDRMAKMQVVNSSYYALVG",
    "output": "Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADKKNLAVRSSYDDYIETVNKITPQLKNLLAQIGGDAAVKGGNNNLNSQTDVTAGACDTKSKSSKCITCKSKSSSSSTSTSKSSKNTSGAPRRRTTATTSFNAMDGQIVQAVTNAGKIVYGTVRDGQLEVRGMVGEINHDLLGIESVNAGKKKPSKKMPTNKKINMSSGMRRQEQINPNDCCLDMGMY",
    "output": "Component of the virion core that undergoes proteolytic processing during the immature virion (IV) to mature virion (MV) transition. Essential for the formation of a structurally normal core."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDSNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRVGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI",
    "output": "Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs). Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell. Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain. This domain is believed to allow recognition of RNPs bound to the protein M1. Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized. Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane. May down-regulate viral RNA synthesis when overproduced."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "SVTIDYDKCKGPECAECVNACPMEVFEIQGDKVVVAKEDDCTFCMVCVDVCPTDAITVKE",
    "output": "Ferredoxins are iron-sulfur proteins that transfer electrons probably in the CO-dehydrogenase complex."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKFAPVQYKYIIKAEFEIDGIVDREDIIGAIFGQTEGLLGMELDLRELQKQGKLGRIEVEYKRVGNKTIGTITIPTSLKAVETSLIAAAIETVDRVGPAKARFRVKEIVDVRSSKREYIRNRAKELFVQLLSKTAPDIEELRRELEEAYYSKQLIEYGEEKLPAGPLVEKSDEIILVEGRADVVNLVKHGILNVLGMNGINIPKSVVELSKRKKVTLFIDGDRGGELVLRNLLAAGADIDYVAVAPPGREVEELTNKEILKALKSKIPLEQYIKNLRISINNDENKEKYKELLSKVFDTKKAIVFDEQFNIIDEKPLEEIDKLPSAYGIAIDKILDNETYAKIKGKYQLILALDSNVNAQERVITLKDIQ",
    "output": "RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEKLLDEVLAPGGPYNLTVGSWVRDHVRSIVEGAWEVRDVVTAAQKRAIVAVIPRPVFTQMQVSDHPALHAISRYTRRHWIEWGPKEALHVLIDPSPGLLREVARVERRWVALCLHRTARKLATALAETAGEAWHADYVCALRGAPSGPFYVHPEDVPRGGRAVADRCLLYYTPMQMCELMRTIDATLLVAVDLWPVALAAHVGDDWDDLGIAWHLDHDGGCPADCRGAGAGPTPGYTRPCTTRIYQVLPDTAHPGRLYRCGPRLWTRDCAVAELSWEVAQHCGHQARVRAVRCTLPIRHVRSLQPSARVRLPDLVHLAEVGRWRWFSLPRPVFQRMLSYCKTLSPDAYYSERVFKFKNALSHSITLAGNVLQEGWKGTCAEEDALCAYVAFRAWQSNARLAGIMKGAKRCAADSLSVAGWLDTIWDAIKRFFGSVPLAERMEEWEQDAAVAAFDRGPLEDGGHHLDTVQPPKPLPRPEIAATWIVHAASADRHCACAPRCDVPRERPSAPAGPPDDEALIPPWLFAERRTLRCREWDFEALRARADTAATPAPLAPRPARYPTVLYRHPAHHGPWLTLDEPGEADAALVLCDPLGQPLRGPERHFAAGAHMCAQARGLQAFVRVVPPPERPWADGGARTWAKFFRGCAWAQRLLGEPAVMHLPYTDGDVPQLIALALRTLAQQGAALALSVRDLPGGAAFDANAVTAAVRADPGQLALTSPPPDNPPPPRRARRSQRHADARGPPPPAPVRDPPPLPPSPPAPRRAGDPASPISAEPADRARDAEPEVACEPGGPATPTRADPDSDIVESYARAAGPVHLRVRNIMDPPPGCKVVVNAANEGLLAGSGVCGAIFASAAATLAEDCRRLAPCPTGEAVATPGHGCGYTHIIHAVAPRRPQDPAALEQSEALLERAYRSVVALAAARRWACVACPLLGAGIYGWSAAESLRAALAAARTEPAERVSLHICHPDRATLMHASVLVGAGLAARRVSPPPTEPLASCPADDPGRSTQRTASPPAAPPGDAAAPESRGCQGCELCRYTRVTNDRAYVNLWLERDRGATGWAMRIPEVVVYGPEHLAAHFPLNHYSVLKPAEVRPPRGMCGSDMWRCRGWQGMPQVRCTPSNAHAALCRIGIPPRVSTRGDERDPNTCWLRAAANVAQAARACGAYTSAGCPKCAYGRALSEARTHEAFAALSQRWIASHADASLDGTGDPLDPLMETVGCACSRVWVGSEHEAPPDHLLVSLHRAPNGPWGVVLEVRARPEGGNPTGHFVCAVGGGPRRVSDRPHLWLAVPLSRGGGTCAATDEGLAQAYYDDLEVRRLGDDAMARAALASVQRPRKGPYNIKVWNMAAGAGKTTRILAAFTREDLYVCPTNALLHEIQAKLRARDIDIKNAATYERALTKPLAAYRRIYIDEAFTLGGEYCAFVASQTTAEVICVGDRDQCGPHYANNCRTPVPDRWPTERSRHTWRFPDCWAARLRAGLDYDVEGEHAGTFACNLWDGRQVDLHLAFSRETVRRLHEAGIRAYTVREAQGMSVGTACIHVGRDGTDVALALTRDLAIVSLTRASDALYLHELEDGSLRAAGLSAFLDAGALAELKEVPAGIDRVVAVEQAPPPLPPADGIPEAQDVPPFCPRTLEELVFGRAGHPHYADLNRVTEGEREVRYMRISRHLLNKNHTEMPGTERVLSAVCAVRRYRAGEDGSTLRTAVARQHPRPFRQIPPPRVTAGVAQEWRMTYLRERIDLTDVYTQMGVAARELTDRYARRYPEIFAGMCTAQSLSVPAFLKATLKCVDAALGPRDTEDCHAAQGKAGLEIRAWAKEWVQVMSPHFRAIQKIIMRALRPQFLVAAGHTEPEVDAWWQAHYTTNAIEVDFTEFDMNQTLATRDVELEISAALLGLPCAEDYRALRAGSYCTLRELGSTETGCERTSGEPATLLHNTTVAMCMAMRMVPKGVRWAGIFQGDDMVIFLPEGARSAALKWTPSEVGLFGFHIPVKHVSTPTPSFCGHVGTAAGLFHDVMHQAIKVLCRRFDPDVLEEQQVALLDRLRGVYAALPDTVAANAAYYDYSAERVLAIVRELTAYARGRGLDHPATIGALEEIQTPYARANLHDAD",
    "output": "[Non-structural polyprotein p200]: Probable principal replicase for the negative-strand DNA, which replicates the 40S (+) genomic RNA into (-) antigenomic RNA. It cannot replicate the (-) into (+) until cleaved into p150 and p90 mature proteins.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "GFLTAEEKGLVNGLWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSSADAIMSNAKVKAHGKKVLNSFSDGLKNIDDLKGAFAKLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGHDFNPQVQAAFQKVVAGVANALAHKYH",
    "output": "Involved in oxygen transport from the lung to the various peripheral tissues."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MATERRVARVAELIKREVSQLLMYEIRDERVGAGMVSVTDVEVSGDLQHAKIFVSIYSTEEVRRSTMAGLKAASGFVRRELGQRIRLRRTPEVVFIEDRSLERGSRVLALLNQIGQQQSTSEVLES",
    "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVSKISKRMQQISQGIDRSALYGLSDAVVMLKERATARFDETVEIAMNLGIDPRHANQMVRGVVTMPNGTGVNVRVAVFATSSKADEAREAGADIVGGEDLFEIVKGGQIDFDRCIATPDMMPLVGRLGRILGPRGIMPNLRVGTVTTDVATAVRESKSGAVDFRSEKAGIIHAGIGKVSFENKKIEENVLAFVSAVVKAKPSVAKGDYVKRVTLSSTMGCGIKVDLSSFSV",
    "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGDSQYSFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKAANGVVIATEKKLPSILVDETSVQKIQSLTPNIGVVYSGMGPDFRVLVRKSRKQAQQYYRLYKETIPVTQLVRETAAVMQEFTQSGGVRPFGVSLLIAGYDDNGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMELDDAIHTAILTLKEGYEGQISANNIEIGIIRSDREFKVLSPAEIKDFLEEVE",
    "output": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKSTAEIRQAFLDFFHSKGHQVVDSSSLVPNNDPTLLFTNAGMNQFKDVFLGLDKRSYVRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIRYAWELLTSPQWFNLPKEKLWVTVYATDDEAYGIWADEVGVPRERIIRIGDNKGGPYASDNFWQMGETGPCGPCTEIFFDHGEHIAGGPPGSPDEDGDRYIEIWNLVFMQFNRQVDGTMLPLPKPSVDTGMGLERVSAVLQHVNSNYDIDLFKTLIDAVAKAVGTTDLTNKSLRVIADHIRSCAFLISDGVMPSNENRGYVLRRIIRRAARHGNMLGATDAFFYKLVAPLIEVMGPAAEELKKQQSVVEQALKMEEEQFARTLERGLSLLDEEIKNLKGDTLDGETAFRLYDTYGFPVDLTADVCRERGLKVDEEGFEAAMTAQRQRARDASGFGVDYNSLIRVDENTPFCGYEKTQQQAKVIALYHNGNAVDQIAAGDEAVVILNETPFYGESGGQVGDQGELKNAGVSFAVQDTQKYGQAIGHVGKLTQGMLRVNDSVDANVDSQRRDRIRLNHSATHLLHAALRQVLGVHVAQKGSLVNDSYLRFDFSHTEAMKPEQIRQVEDIVNAQIRRNLTVQTDVMALDDARAKGAMALFGEKYDDHVRVLSMGDFSIELCGGTHASRTGDIGLFQIISESGTAAGVRRIEATTGENALSALHRQSDVLQDIAQLLKGDSHNLTDKVRSVLDRSRALEKELQQLKAQQAAQESSSLSGKATEINGVKLLVTQLDNVDPKLLRTMVDDLKNQLGSAVIVLGTAAEGRVSLISGVTKDLTDRVKAGELVGFVAQQVGGKGGGRPDMAQAGGSDVSALPAALASVESWVAAKL",
    "output": "Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIKQRTLKTPVKATGVGLHSGVKVEMTLRPAAPDSGIVFRRVDLEPPAELKADPYLVTDTRLCSMLESGAAKVSTVEHLMSALAGLGIDNLLVDLTGPEIPIMDGSSAPFVFLLQSAGIVEQNAAKRYVRITRPIEVRDGDKWARFVPHHGFKIEFTIDFKHPVFDKSGKTVTIDFADTAYTKEVARARTFGFMHEVEYLRNQGLALGGSLDNAIVMDEYRVLNQDGLRYDDEFVKHKVLDAIGDLYLLGHPIIGAFEAYKSGHALNNALLRELLQHREAWEFVSFEHDEDVPSAFLRLHPLAA",
    "output": "Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPRKGHVQKREILPDPMYNSKLVTSLIDHLMIDGKRGTATKILYAAFDEIKNETGNDPVEVFQQAMENVMPVLEVKARRVGGSNYQVPIEVRPDRRTTLGLRWIVQYARLRGEHTMVERLAREIIDASNNTGASVKKREDTHRMAEANRAFAHYRW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "VPTQRLCGSHLVDALYFVCGERGFFYSPKQIRDVGPLSAFRDLEPPLDTEMEDRFPYRQQLAGSKMKRGIVEQCCHNTCSLVNLEGYCN",
    "output": "Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNETAKKLLVTGATELGLHLTSAQLGNFYTYASELTKWSKKINLTAIKTDEEIALKHFVDSLTLAKVVKNKGRLLDIGSGGGFPAIPLKIVLHDLHVMSVDAVEKKVIFQRHVARLLHLHDFEAVHVRGEELAKSHAGQFDWIVSRAFSDIPTFAAMTLPLLKSDGRLIAMKGRGGRDEAEAAKGALDDLGARIAELLEFRLPVSGDSRYLVVMEKVAD",
    "output": "Specifically methylates the N7 position of guanine in position 527 of 16S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSVSFAPAHSASPPNTSYIALAGPTASGKTAAALAIAEHVPVEIISVDSALVYRGMDIGTAKPSAEELAAVPHHLIDIRDPLHAYSAAEFVLDAQRLIAQISARGRLALLVGGTMLYFKALFDGLDEMPKADAAVRAVLAIEAAEKGWPALHAELAQVDPVTAARLAPNDSQRISRALEVFRVSGQPLSFFQQRNASKNIADNAGGTSAATLISLEPTDRAWLHGRIAQRFDAMLASGFVDEVRALRARGDLTPDLPAMRCVGYRQAWEALDGTSPMSELRDKGVFATRQLAKRQITWLRSMPQRRVVACDDPTALEQVLDLVKARTDAFQ",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTRRLFILITIMLCLIPALLHSQEGYREVTAAGTHKLTLTVDSPRRLGGSDAPQVARETAEALQFDMVLAGPFTVTAPSAAAASAGIRPGEFDFAPWRGAGVDLLVKSGYTVTGNAMTMEFRLYNVTQGKEILAKRYTGRPGDVRRIAHTFSDDIMAALTGERGPFTGKIAFVSTRAGAKAIFLMDYDGHNVQQLTKNRSINLNPDFSPSGKEIIFTSYRQGNPDLFRRELFTGAEARISSYRGINATGAWSPDGKTIALTLSKDGNSEIYTISRDGKNPHRLTNTSAIEVSPAWSPDVRKIVFVSDRLGKPQIFIMNADGTGVRRLTTSGNYNVSPRWSPKGDRIVYSRQEGGFQIYAINPDGTNDTRLTSEGSNEHPRWSPDGRFITFSSTRGGGEGIYVMRADGSGQTRVSGGKGRDSHPTWSPRW",
    "output": "Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEILGFTVMGGGSPAWIEVPEKSKSAFWELMRRKVHRYVIFKIDDRREEIVVEKTGAPWESYDDFTASLPADAVYDLDFVSDDNCRKSKIFFISWSPSLSCIRAKTIYAVWRNQFRHELDGVHFEIQATDPDDMDLEVLRGRANRT",
    "output": "Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQIFVKTLTGKTITLEVEFSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGL",
    "output": "Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, and DNA-damage responses. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKEVAGKLRLQIRGGAANPSPPVGPALGSKGVNIMEFCKQFNAKTQDRIGKLLPVVVTYYVDKSFDFVIKNPPVAVQLLEIVKLKSGSAEPNRKKIAEITWEQVKAIAEYKMADLNCFSVEKAIQMVIGTAKSMGIHVKRDFSEKQLNS",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPSALSYTNPGSSLVSPSLAASSALADTSMLSPPQATLHRNVSPGAPQRPPSTGSAGGMLSTSDLTVPNGAGSSPVGNGFVNSRASPNLIGTTGANSLGKVMPTKSPPPPGGGSLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQHHLGQAALNSLVAGGQLSQGSNLSINTNQNINIKSEPISPPRDRMTPSGFQQQQQPQPPPPPPQAPQPQPRQEVGRSPVDSLSSSSSSYDGSDREDPRGDFHSPVVLGRPPNSEDRESPSVKRMRMDAWVT",
    "output": "Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTAELKASDTEMTKPEERHLLQLLAQLEKVPHHQLEQKFVAYFKKVGKGDNQSNCTLEDFATYFLGALRQSTKRYYYSQNSETPVFPLTPIHQLKPPVADVVKEEEQQQLNESSILSRSSCSMSSTSNTTPAPQQPQGRRSTPGSGAQFCSTPNRSGGGGAGGGHSICLGNFLVNTPIQSHQRSKKKITPQKQQQNQHASLGSGTGAGATPQSKPRRRVLPMTISKNVSASSSFGDTSSFSNENNFWRISQSSEIFDRSQEAALEMEARKFLLLKKQEIKSEAPVNVSQQERTPEDEVFPEEAISLEGVANANHLQLLSTIYSLLMDLNLVPNVLRELSFVVHLLNVRDFGQSPVKSYVPSALEGLTQHKSCVYFAAKLLENQKKLLLQLDKRTLSVLLQNERLSLLPQGVVQELETHCQRRQDSTTPFAMDTSSSSQQNVYYHVENDSRDNFPSQNEFGAFKSQRDLFYKALKRWEVSHLNRGFNFPSELGPRIMDIYKKSEHPVNMTHLAKLFVNQLLISATETTESPEELGLKLDPLRHNKLAQRLVTSSSSVEGQFPRSQAFFRDFIAVCSSVAFLVHLKLELFVQLMRNNDSTFDLLQLTDDVAVEEQSAQQGPYIVRVQTMANMLILAKFLGYVTVMPFSGTTQHGNPTPPYLCPQQLQLRNHFRPDFNLREILERSMRQGKLLITLPWLVQYLAMLDLVSLHLPDAVATLELLYGLYADIRMAKLQPAAVFIARSCIGWLLDAQPQLVNGYYNYRAQEAGVGSISAIVDICLKDLSCHDKSHAPLLDELLPVACPFLQEFRVSITPSRQAKSGRFRYITTRLEQLQQNSSSISKDAIVASELSPAEQQQRKLVDAYLQSQNASTRRLIEFVTERTFKCVVKDAQQEILLPSKASADAKVNEIKSTMLEEVFQELHEIFQDARENACQRWKEHVHQMLDRRIEHSLDGLLPSSTNAVLRSTYAHLIRVQAQTQLQQWLQSSVLQSTFYHGDLQELATKVCNCNRNKADAAAAGGGGSSELQLSPDIGFSLSEFLYQLQQWLHCLSLRPEYVGSQEDLAELLRKAQKAVLLPKMPTVFYHLIGSGLVHLLQLLITRKPNFLDKDIISASCSVWRSQQLMDSKASPGIFDGLISISFVQEMANSADSFRMLETILRSMLQSGAIRADHLNELFMPLFAENWSPKVWCMLSELLQQLSLSGKDSEAHYASGDSPEDEAKSHLFMEMLADLSRDLDNF",
    "output": "Regulator of cell proliferation and cell survival of differentiated cells independent of cell division. Essential for imaginal disks formation. Not involved in cell polarity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFVSRLAASGLLLLALLALSLDGKPVQEKPGRSPPISPLLVPPPPPPPHWPPPHHIPPLSVQKFPPGWKPTHPHHIPPLEVQQWSQGGPRSELVQPHESPAGGTTAFREELSLGPEAASGPAAPQRLPKRKGASATSAASRSMRDLRADGKQARQKWGRMVQPDHHAAPGGGGGGGGGARRLKGLAKKAVGKGCFGLPLDRIGSMSGMGC",
    "output": "Bradykinin-potentiating peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it. It acts as an indirect hypotensive agent (By similarity). Tg1 does not show bradykinin-potentiating effects.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRAIIIGIGQCGGKIADIFSLVDFEAIAINTSRGDLEYLKHIPQDKRILIGESIVGGKGVNANPVLGREAMKRDLPMVMKKINSMVGYEDVDIFFLTFGFGGGTGAGGTPVLAEALKEEYPDSLVVAIGALPLKEEGIRPTINAAITIDKLSKVVDSIIAIDNNKLKESDEDISQAYERINYTIVERIASLLALIDVPGEQTLDASDLKFVLRAMGSFATVGYAKADAEKVKSLSRLIIRSFENEGLYLDVSLESALYGLVAIHGPPEVLKAKDIFEALNELTQRIRGKQIFRGFYPDPRERSVEVVTLLSGIYESKSIEDIILTAKKYAREFMKAKEEGEAKKRELLSGLPDFDDVYSGEESEG",
    "output": "Involved in cell shape control."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAAKPENLSLVVHGPGDLRLENYPIPEPGPNXVLLKMHSVGICGSDVHYWQHGRIGNFVVKKPMVLGHEASGTXVKVGSLVTHLKPGDRXAXEPGA",
    "output": "Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with xylitol, L-iditol and D-sorbitol (D-glucitol) as substrates, leading to the C2-oxidized products D-xylulose, L-sorbose and D-fructose, respectively (By similarity). Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPSRNILVINCGSSSIKFALVNEAHSLFPLHGLAERLGSRDAVLRWKRGGDSDSLMIPNADHRAALAQLLPMVQNAAGGKLHGIGHRVVHGGELFTHATRIDDRVVEAIRATAPLAPLHNPANLQGIEAAMTLFPKLPHVAVFDTAFHQSLPEHAYRYALPEALYREHGVRRYGFHGTSHRYVSHRAAEMAGLAVGDSSWLSAHLGNGSSTCAIVNGQSLDTSMGLTPLEGLVMGTRSGDVDPNLHSHLARTLGWSLERIDSMLNNESGLLGLSDLSNDMRTLEQEREQGHPGAALAIEVFCYRLAKSLAAMSCALPQLDGVIFTGGIGENSPLVRAKTAAHLRLFDLRLDQEANARCVRGVAGPIQAAGHPRVLVIPTNEERQIALDTLALLD",
    "output": "Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNQADLTERSDALQEQILNLYEQDSKDIQAQIQYWDLNRKLYVTYYYARKEGYSHLGLQPLPALQVSEYKAKQAIEMGLLLTSLSKSQYASELWGLTDTSAELLLTPPRNTFKKKGYTVNVWFDNNENNTFPYTNWEYIYYQDDIEQWHRTRGEVDYNGLYFTENNGNRAYFLLFDSDAQTYSQTGTWTVHYKNQIISAPVTSSSKQSSDDYTSKAGQQPHFFASSSSPTTTDGGQTSQEGVSSSTTSPSAVRLRRRRSNEQQRELSSRESPRTKRRRVPDEVDRQSAVGSAPTAEEVGSRHRSLPRSGISRLARLQGEARDPPILLIKGLANSLKCWRYRLKKYTRYFKCMSTVFRWVDIDVPESSRHKLLVVFNDTTQRDVFMKLVTLPRGCTYTFGTLNSL",
    "output": "Plays a role in the initiation of viral DNA replication. A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity. Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA. E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome. Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box. Repression occurs by sterically hindering the assembly of the transcription initiation complex."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MISSNDFRTGTTIELDGAVWRVIEFLHVKPGKGSAFVRTKLKAVQSGSVVEKTFRAGEMVPQALLEKTTLQHTYMDSGDYVFMDMSSYEETRLTAAQIGESRKYLTEGMEVNVVSWNERPLEVELPNSVVLTVKETDPGVKGDTATGGTKPAILETGAQVMVPLFISVGEKIKVDTRNDSYLGREN",
    "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSDNSPTTPSAPAPEEVEAAMAAHADDELARLQGELAELKAKSAELADQFLRAKAEAENARRRAEDEVAKARKFGIESFAESLLPVADSLDAALAIKEATPQQLREGADATLRQLTSTLERNKVLAINPAAGTKFDPHQHQAISVVPAEQEANTVVAVLQKGYVIAERVLRPALVTVSASK",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKFAVLVFPGSNCDRDMYNAAIKSGVDAAYVDYRETTLDGFDGVLIPGGFSFGDYLRSGAMASVAPIIKEVKRFAKEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNETLKITNNQTPFTHLYVKNENVVYPVAHGEGHYYCTDEIYRELNDNNQIILKYTNNPNGSYEDIAGIVNKEGNVCGMMPHPERALETLLGTNSGVKLFESMVKSWREQNV",
    "output": "Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MMHIPNRSIQAANIFFSSGAILLLIVGLIMEDWVELIPKVRKDKTTHSPWLGCCPPFWPEESLEVVRRIMRMTLNISIYLNLIIGLQFSYMISQNKCVHLLVGFLSFFAGCLLFYAIIVYHHKLNKGQYVYFVNYKTKWIAFTVYLTIALFLTCGIFCFIQSTNRCECMKFCIPHTESKSQEMIPSTIEVVSLPPRCAMPRSIVHVHSVTSKDGSLNRPHTQARRVTWAL",
    "output": "Probably inhibits protein phosphatase 1 (PP1) in sperm via binding to catalytic subunit PPP1CC."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP",
    "output": "Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4-hydroxynonenal (4-HNE)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKKNLTFFMVIALLFTITPNVYAMHIAEGFLPPMWSGVYFVISAPFIIIGLKQIRERAKDNKDIKMLLGLVAAYAFILSAMKIPSVTGSCSHPTGTGLSAIIFGPFISAIVGLIVLIFQAILLAHGGITTLGANTLSMGIMGPIVSYLIYRGFKNKNQKVAVFLAATLGDLFTYFITSVQLALAFPAQQGGIAASFAKFFSIFSITQIPLAIMEGILTVIIFEFVMKYASKEIEVLGGVRK",
    "output": "Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLPVHTEVKPNPLQDANLCSRLFFWWLNPLFKAGHKRRLEEDDMFSVLPEDRSKHLGEELQGYWDKEVLRAKKDARKPSLTKAIVKCYWKSYLILGIFTLIEETTRVVQPIFLGKIIDYFEKYDSDDSAALHTAYGYAAVLSLCTLILAILHHLYFYHVQCAGMRIRVAMCHMIYRKALRLSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIGVTILLWVEIGISCLAGLAILVILLPLQSCIGKLFSSLRSKTAAFTDARIRTMNEVITGMRIIKMYAWEKSFADLITNLRKKEISKILGSSYLRGMNMASFFIANKVILFVTFTTYVLLGNKITASHVFVAMTLYGAVRLTVTLFFPSAIERVSEAVVSVRRIKNFLLLDELPERKAQEPSDGKAIVHVQDFTAFWDKALDTPTLQGLSFTARPGELLAVVGPVGAGKSSLLSAVLGELPPTSGLVSVHGRIAYVSQQPWVFSGTVRSNILFGRKYEKERYEKVIKACALKKDFQLLEDGDRLVIGDRGARLSGGQKARVNLATAVYQDADIYLLDDPLSAVDAEVGKHLFQLCICQTLHEKITILVTHQLQYLKAASHILILKDGEMVQKGTYTEFLKSGVDFGSLLKKENEEAEPSPVPGTPTLRNRTFSEASIWSQQSSRPSLKDGVPDAQDAENTQAAQPEESRSEGRIGFKAYKNYFSAGASWFFIIFLVLLNLMGQVFYVLQDWWLSHWANRQGALNDTKNANGNVTGTLDLSWYLGIYTGLTAVTVLFGIARSLLVFYVLVNASQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTFLDFIQTLLLVVSVIAVAAAVIPWILIPLVPLSIIFVVLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAVFVIVVAFGSLVLAKTLDAGQVGLALSYSLTLMGMFQWSVRQSAEVENMMISVERVIEYTDLEKEAPWECRKRPPPGWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHSDEELWKALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKKNRILIIDEATANVDPRTDELIQQKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLREYDEPYVLLQNPESLFYKMVQQLGKGEAAALTETAKQVYFRRNYPDIAFSSPAVMSTSNGQPSALTIFETAL",
    "output": "ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells. Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates also the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4). The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH). Transports a wide range of drugs and their metabolites, including anticancer, antiviral and antibiotics molecules."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAHACVSTSASSLRFTAGFVSASPNGSSFDSPKLSLPFEPLRSRKTNKLVSDRKNWKNSTPKAVYSGNLWTPEIPSPQGVWSIRDDLQVPSSPYFPAYAQGQGPPPMVQERFQSIISQLFQYRIIRCGGAVDDDMANIIVAQLLYLDAVDPTKDIVMYVNSPGGSVTAGMAIFDTMRHIRPDVSTVCVGLAASMGAFLLSAGTKGKRYSLPNSRIMIHQPLGGAQGGQTDIDIQANEMLHHKANLNGYLAYHTGQSLEKINQDTDRDFFMSAKEAKEYGLIDGVIMNPLKALQPLAAA",
    "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKKKGGATTRSGKKKVCVFCKENIEYVDYKDYNMLRRFTSERGKIRARRVTGLCPQHQRETARAIKRAREMALLPYIAGR",
    "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKLHELKPAEGSRKVRNRVGRGIGSGNGKTAGKGHKGQNARSGGGVRLGFEGGQTPLFRRLPKRGFTNINRKEFAIVNLSTLNRFEDGTEVTPELLLETGVISKLNDGVKILASGAVEKKLTVKAHKFSSSAKEAIEAAGGSVEVI",
    "output": "Binds to the 23S rRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNVSAIVVEYNPMHNGHLYHIKKTKKLTNCDALVCIMSGNFVQRGFPSILDKWTKANIAISNGVDLVIELPTLYSLSSAEFFSFGAVSILDSLNIINSICFGSEIGNINALQDIATTLLEEPLEYKILLKNYLDKGISFAKARNLALVELNRDNKIMSENISKILSLSNNILGIEYLKSLLLLNSSIKPFTITREGADYKDENLHEEYSSASSIRKYLKENKNINILKDFLPLEGFLEFKRLITKGYNFSMEDSMINYIRYKYISGYKNLHNLIDVSEGLDNRIYKSLEKNFTYDSLVGEIKSKRYAYSRIGRILCQYFIGFENYDLNSLLKSTPNYMRVLASNEMGLKVLKKIKKHSSINIYTKLPKNTNTLLSLDIKATNAYSLLNNNIRFNEDYFRSPTIIKNTIY",
    "output": "Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MALDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMDDEAIREFNPRGIILAGGPESVHEANSPRAPQAVFDLNVPLLGICYGMQTMAEQLGGKVEGSDLREFGYARVDVVGKSRLLDGIEDHVDGDGVLGLDVWMSHGDKVTQMPGNFNILASTPSCPIAGMFDDARGYYGVQFHPEVTHTKQGGRILSRFVQDICGCEALWTPSNIVEDAIAQVRQQVGSANVLLGLSGGVDSSVVAALLHRAIGDQLTCVFVDNGLLRLHEGDQVMAMFKENMGVKVIRADAEKQFLDNLEGEADPEKKRKIIGRTFIDVFDAEASKLDNIQFLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRKIGLELGLPYDMVYRHPFPGPGLGVRILGEVKKEYADILRRADHIFIEELRKADWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETVDFMTARWAHLPYDLLETVSGRIINEIDGISRVTYDVSSKPPATIEWE",
    "output": "Catalyzes the synthesis of GMP from XMP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "GGSCGQCRVHIKEGGGDILPTELDHISKGEAREGCRLACQVNVKNDMEIELEESIFGVKKWDCEVISNDNKATFIKELKLQIPDGESVPFRAGGYIQIEAPAHHVKYADFDIPEEYRGDWNHFGFFDLESKVDEETIRAYSMANYPEEEGIIMLNVRIATPPPRNLSLPCGKMSSYIWSLKEGDKVTISGPFGEFFAKDTDAEMVFVGGGAGMAPMRSHIFDQLKRLNSKRKISFWYGARSKREMFYVEDFDGLAEQNENFVWHTALSDPQPEDNWEGYTGFIHNVLFENYLKDHEAPEDCEY",
    "output": "NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPKANNAVASKARRKRVLKKAKGYWGSRGNILTVVKHAVDKGEQYAYRDRRAKKRSFRSLWIIRINAAARLNGTTYSRLMDAMIKKNVEIDRKTMAEIAVRDPEAFTQLVKTIID",
    "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST",
    "output": "Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVMTDPIADFLTRIRNANMVKHDKLELPASKIKKEIAEILKREGFIRDVEYIEDDNAGTIRVFLKYGATGERVITGLKRISKPGLRVYAKSTEVPKVLNGLGIAIVSTSQGVLTDKEARAKQVGGEVLAYVW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQSPEKITPYDTECPKNEQVEAMFNHIAGHYDRLNHLFSWGMDRVWRQKAIRMIEPFAPHTVLDVATGTGDLAIEICRHIPSVKQVTGVDLSLEMMRIGEQKVRSENLDNRITFMQKDCLDLPFADHSFDAVTVAFGLRNFQNIKLGLEEMYRVLNEGAPLMILELSRPVSFPWKQGYNFYASHVIPVVGRFLSQDAEAYTYLPESIAAMPQREELADLMLSVGFREAYYRSLSLEVATVYMGLK",
    "output": "Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKSKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLSSKFGGEAKAYDQIDAAPEEKARGITINTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYIIVFLNKCDMVDDAELLELVEMEVRELLSKYDFPGDDTPIIKGSAKLALEGDKGELGEGAILKLAEALDTYIPTPERAVDGAFLMPVEDVFSISGRGTVVTGRVERGIIKVGEEIEIVGLKPTLKTTCTGVEMFRKLLDQGQAGDNVGILLRGTKREEVERGQVLCKPGSIKPHTHFTAEVYVLSKDEGGRHTPFFNNYRPQFYFRTTDVTGAIELPKDKEMVMPGDNVSITVKLIAPIAMEEGLRFAIREGGRTVGAGVVAKIIE",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSLNPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWGCVNQTLEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHMGHVSMMHGVDPNPHMSLYAAKASGMMGLTAEMLGKMHGISREQQDAFAVRSHQLAHKATVEGKFKDEIIPMQGYDENGFLKIFDYDETIRPDTTLESLAALKPAFNPKGGTVTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPATQKALKRAGLNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGARISGTLLNVMKQNGGTFGLSTMCIGLGQGIATVFERV",
    "output": "Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLPLLGLCFALPLCAGLLEEARSWEDTSDQVGLRIPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVACRMLNRGSEDQEVTFQMQIPAAAFITNFTALIGDKVYQGEITEREKRNGDKVKEKRNKTIEDNGEKGTETFRASAVLPSKDKAAFLLSYEELLQRRLGKYEHVVSVRPQQLVGRLTVEVTVLERPGIAELEVLGLQNSRQRGSGRGPDDSGPPPSTVINQNETFAKVVFKPSVVQQAKIAQNGILGDFIVRYDVNREQSIGDIQVLDGYFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDHFNIVGFSNRIKVWKDHLVSVTPNSIRDGKVYIHHMSPSGGTDINGALQRGIQLLNDYVAHNDIEDRSVSLVVFLTDGKPTVGETHTFKILNNTREATRGRVCIFTVGIGADVDFKLLEKLSLENCGLTRRVHEDHDARAQLIGFYDEIRTPLLSDIRVDYPPSLVERATRTLFPNYFNGSEIVIAGKLVDRAMDRLHVEVTASNSKKFVVLKKDVPVEPRKVGIDVSQSPRPRGRGQEEPNHLERLWSYLTLKELLSAWLQSIEEPERERLRQEAQALAVNHHFLIPFTSMTLKSAPRTEAPEAAYGMSSTSMATGPETVMQSLRGTHLQPGPAVKKPYNPRIKISKTSADGDPHFVVDFPLSNLTVCFNIDGEPGHILRLVSDHADSGVTVNGELIGAPAPPNGHKKQRTYFRTITILVNKPERSYLEITPSRVIVDGGDRLVLPCNQSAVVGRRGLEVSVSANASVTISIQGTVAFVVLLHLYKKPAPYQRNHLGFYIANGQGLSSNCHGLLGQFLNQEARLIGLSKSPAHPPVPEAGERSEAVLEVKGRQVPVVWKQRRIYNGEEQVDCWFARNNAAGLIDGEYKGYLAAHPFDSETAFGPGLSQGL",
    "output": "May act as a tumor suppressor."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATIHFTKVHGSQNDFFLVDEEGNQIMDWSDAKRADFAIKLCDREHSLGGADGILYVTKSSEAGPIGQMRVVNSDGSIASMCGNGLRTVARYLLEKHALTEAKVETMKAILDVKKATSLGFDIPTYQVEISPVKFNAESLPMNVGVEKLFNQVVPELDAELAFSAVSVPNPHLITFVDQTVLDSDRQETLASYLNSENPYFPDGVNVSFVKRLSDDAIYVRTFERGVGFTNACGTAMSACSLIKKMLDKDTFETPLNVYNDGGRVQVTAKKDEAGDISLQLIGNATFVSTGSVSYESDTVTELTNEATPEQAQYQELVKEVKEFLKTTE",
    "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAVQAFHLTNDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPAEVAYGA",
    "output": "Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVKDILAPGLRVVFCGINPGLSSANTGFPFAHPANRFWKVIHLAGFTDRQLKPEEAEKLLDFRCGVTKLVDRPTVQATEVKLHELRSGGRNLIEKIEDYQPAALAVLGKQAFEQGFSQRGIAWGKQKIAIGATMVWVLPNPSGLNRIKTEKLVEAYRELDQALIMRGL",
    "output": "Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNIAEFHQNIEHVWQKIEEELENQGADVDCETQGSVFTITFDNRTQIVINKQEPLLELWIASKLGGFHFAFKNGEWVSNDGQRFWDCFVEACAAHGENVQF",
    "output": "Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIKEHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAFRENVLEILEEITETEEVVQNTNIKLFDEGLLDSMATVQLLIEIEEKLDITVPVSEFDRDEWATPEMIITQLEALK",
    "output": "Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLG",
    "output": "Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISLIRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVTVPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIEKTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFLLSGYEYFLGFLLIAAAVPILALVTNLIVAPKGRNGERKLTYESGMEPIGGAWIQFNIRYYMFALVFVIFDVETVFLYPWAVAFNRLGLLAFIEALIFIAILVIALAYAWRKGALEWS",
    "output": "NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGLTGTNTTLVAPQPKGILDPRTGKPVGSDDAFFNDLNGELSDKGFIVTSADALITWARTGSLMWMTFGLACCAVEMMHISMPRYDAERFGIAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRVVPVDIYVPGCPPTAEALLYGILLLQKKIRRTGTIER",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVKVGINGFGRIGRLVTRAAFLTKKVEIVAINDPFIDLDYMVYMFQYDSTHGKYKGEVKAEGGKLVIDGHAITVYSERDPANIKWGDAGATYVVESTGVFTTIEKASAHIKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLTVVSNASCTTNCLAPLAKVINDNFVIVEGLMSTVHAITATQKTVDGPSGKLWRDGRGASQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTVRLEKPAKYDEIKKVVKAAADGPMKGILGYTEHQVVSTDFNGDCRSSIFDAGAGIALNDHFVKLVTWYDNEFGYSNRVCDLMAHMASKE",
    "output": "Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity). Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFCYQCEQTDRTGARPGCASAKGNCGKDSTTADLQDLLVHAVKGIAQYGAIARTMGVPDREAERFVLYAMFTTLTNVNFHAARFVALLREAAQTRDRVKAACEAHARAAGTAVPVLHGPAEWQPADDLAGLLKQAASVGIDAGLDTVGADIVGLRALVLYGLKGVCAYAHHAQVLGYERDDIYEGVDAALAFLAGNPADVDALLAHALDLGRLNLTVMELLDNANTGRFGVQQPSAVRVSPVAGKAILVSGHDLGDLHALLEQTAGTGIQVYTHGEMLPAHAYPSLKAFPHLAGNYGGAWQDQQSDFARFPGPILMTSNCIIEPLPQYRQRIFTTGPVGWPGVRHLEHHDFPTLIRAAQALPGFQATAPEQTITVGFGRHAVLGVADKVIDAVKAGQIRHFFLIGGCDGAAPGRNYYTEFAEQAPDDTVVMTLGCNKYRFNRHAFGDIGGIPRLLDIGQCNDSYSAIRIATALADAFECGVNDLPLSLVISWFEQKAAAVLLTLLALGIRNIRLGPTLPAFVTPGVLAVLVDQFGIQPIGDAGADLAAALARRAA",
    "output": "Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRLRNKPWAEDYLRKHNTVVDLDGTHAGKMSEWFEKDQPIYIEVGSGMGQFITELAAQHPEVNFVSLERDKNVMIRVLDKVLEKDLQNIKLICNDAMELTDYFKDGEVDRVYLNFSDPWPKKRHAKRRLTYHSFLALYKAILKDEGEIHFKTDNRGLFAYSLESMSQFGMYFTKINLNLHDEDDEDNIETEYELKFADKGSRIYRMEAKFH",
    "output": "Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPPQIPNENDDLFTRWLKSRAIIQRAVSTRECFDSEVFLASGGWNITNEIITLKKYYQLKWPNSSCNSFHPKTVEFIKERLHNLEEHDSSWKIPNPAYSFKKAFLEDTKSAFSNLEPVWGPSRLLNPAELLLPQDEKLLVQEIPLEFAPFQYTNRFAYGGLQFKNNLFVTYGSYSFLAAGQCVEVHNFDILLNVSSLEICHALLPVIIPDDGDVRNFRNSSYVKFKDTQFNSIPELCSINFMKICNFMHQDFLLACGDNGIVYIWEINKVIKIFNKFTSDILGGKDNSRERYINVDPYMVLRVEESCWSVDVIDINGIIYIAVGHNKPGVTVFAFDKDVKKERRYIRPLDLPSSHNVPCVNFVPNSKDSVGYITLSYCSIFGNVVTVKLKEHDCTILTSFLDTQFFGDDLWTITPLTKKDFAKVDNFELLNLNYQDGFKESMLYSICRDDFLLGYYCDNAYLSGNFGIGTLLNQFQVPVTDLRLTSSAGIPDEVIPLRFTSFDRNYTTTGSIKYEYSREDFALILHAGDLDDMNDAVTKNTSCEQHLHQWTFWEDSGYKHYRATERGFSKYKDIINTFPQLITPSGRNKTSQYQNTSGRKICEPSTYKLTDLENDIEDISREFNRSIRNLKMDKQRQLRTSKEFKSLSSVNHIPNIESGNFLWYNTDAAADWRTLFGKDLNTVLKDPEICSLQLNSTEEDDVNSDPENEESGSSLTSFQRRYRDTEQRAHLKSESQKSWGFHNYVRNVKRLLESAVPGSEDSPLGYQLSEMHDEFFFLTTAHRLVLMKANPLIIISATHHEIFPLDGVVTCASKSLLQALNRINFVCHIKELNCIAVASQLGLISLLRLTEYRGIYSFRQEYILGWEVQDPVNPSPECRCNRNLFDAPMYGADGESSDTYCGVCDVYFPMGDICGLDYTYASDSEELKRKGYATLYVASRGSLRAFKITTEHGTTQQ",
    "output": "Substrate targeting component of a cullin-RING-based E3 ubiquitin-protein ligase complex RTT101(MMS1-CRT10). RTT101(MMS1-CRT10) may regulate nucleotide synthesis through transcriptional regulation of RNR genes encoding ribonucleotide reductases."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH",
    "output": "Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAIVGTIIKIIKAIIDIFAK",
    "output": "Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKEGIHPEYHEITVTCSCGNEFKTRSVLSKPLHIEVCSSCHPFYTGKQKIVDTAGRVEKFNQKYGRHLQKQAQT",
    "output": "Binds the 23S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKVLFVIGSGAKHLEEEISRHGNLINVEIKKFPDGEKYVRVLERGKEAIVIQSTYHPQDENLIEALLLGDALSEAGFKKLKIVIPYLAYSRQDRVTKEGEPISVRAIMKMLGLYYDELYVFDIHNPKTLEHFPGIAKNIYPAEAIANYFKDKLGEGLILAPDKGALERAKRVAEVLGLEYSHFEKERISPTEVRMKPVDVDVNGKNVLIVDDIISTGGTMIKAANILRELGAKEIFVVATHGVFAEGAIERVSKAVNELAVTNTIPTEVSKISIVDYIVKLGEKE",
    "output": "Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATGVFAGLIVGGYGMLAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPAGARTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGPVVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPVLFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVRQTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFLLSAASAFVAGVAVNWRGTLDGAGYVELPTYAFDKRRFWLSAEGSGADVSGLGLGASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVLFPGTGFVELAIRAGDEVGCSVLDELTLAAPLLLPATGSVAVQVVVDAGRDSNSRGVSIFSRADAQAGWLLHAEGILRPGSVEPGADLSVWPPAGAVTVDVADGYERLATRGYRYGPAFRGLTAMWARGEEIFAEVRLPEAAGGVGGFGVHPALLDAVLHAVVIAGDPDELALPFAWQGVSLHATGASAVRARIAPAGPSAVSVELADGLGLPVLSVASMVARPVTERQLLAAVSGSGPDRLFEVIWSPASAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALAAVQSWLTDHESGVLVVATRGAMALPREDVADLAGAAVWGLVRSAQTEHPGRIVLVDSDAATDDAAIAMALATGEPQVVLRGGQVYTARVRGSRAADAILVPPGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFRDIMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTLVAGDVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHAGTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEFEDKFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGVIAQQYPGVRYRAFDLFEPGRPRMHQYMLELATLFGDGVLRPLPVTTFDVRRAPAALRYLSQARHTGKVVMLMPGSWAAGTVLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRAALAKVIADIPVQHPLSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGLDAADLARLGREGVLALSTAEALELFDTAMIVDEPFLAPARIDLTALRAHAVAVPPMFSDLASAPTRRQVDDSVAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAGLPQEIKHTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMFAAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPAGARTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGPVVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWGHDENLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAEVDIAAVNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTIGVISNVTGQLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVTTMSALRKDRPEPATLTNAVAQGFVTGMDLDWRAVVGEAQFVELPTYAFQRRRFWLSGDGVAADAAGLGLAASEHALLGAVIDLPASGGVVLTGRLSPSVQGWLADHSVAGVTIFPGAGFVELAIRAGDEVGCGVVDELTLAAPLVLPASGSVAVQVVVNGPDESGVRGVSVYSRGDVGTGWVLHAEGALRAGSAEPTADLAMWPPAGAVPVEVADGYQQLAERGYGYGPAFRGLTAMWRRGDEVFAEVALPADAGVSVTGFGVHPVLLDAALHAVVLSAESAERGQGSVLVPFSWQGVSLHAAGASAVRARIAPVGPSAVSIELADGLGLPVLSVASMLARPVTDQQLRAAVSSSGPDRLFEVTWSPQPSAAVEPLPVCAWGTTEDSAAVVFESVPLAGDVVAGVYAATSSVLDVLQSWLTRDGAGVLVVMTRGAVALPGEDVTDLAGAAVWGLVRSAQTEHPGRIVLVDSDAPLDDSALAAVVTTGEPQVLWRRGEVYTARVHGSRAVGGLLVPPSDRPWRLAMSTAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANFRDVMIALGLYPDPDAVMGVEACGVVIETSLNKGSFAVGDRVMGLFPEGTGTVASTDQRLLVKVPAGWSHTAAATTSVVFATAHYALVDLAAARSGQRVLIHAGTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEFEDKFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGVIAQQYPGVRYRAFDLFEPGPDRIAQILAELATLFGDGVLRPLPVTTFDVRCAPAALRYLSQARHTGKVVMLMPGSWAAGTVLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRAALAKVIADIPVQHPLSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGLATVDFKRFARDGIVAMSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSATGLALSPTLIFDYPNSAALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPVKRLRQAGVLDLLLALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE",
    "output": "Involved in the synthesis of beta-D-mannosyl phosphomycoketide (MPM), an antigenic mycobacterial polyketide . Binds a fatty acyl-CoA as a starter unit, and extends it by five rounds of alternative additions of malonyl-CoA and methylmalonyl-CoA extender units. Depending on the starter unit, the enzyme forms mycoketide-CoAs of different lengths . Shows preference for small-/medium-chain starter fatty acyl substrates . Uses a hybrid modularly iterative mechanism, by forming a supramolecular assembly to perform repetitive cycles of iterations ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPADLSGTWNLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIQTCSSLRNYLVKFKVGEEFEEDNKGLDNRKCTSLVTWENDKLTCVQRGEKKNRGWSHWIEGDQLHLEMFCEGQVCKQTFQRA",
    "output": "Intracellular transport of retinol."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNATTINSLFLIGALLVSASILVSSLSSRLGIPILVIILAVGMVAGVDGGGIIFDNYPTAYLVGNLALAVILLDGGLRTRVASFRVALWPALSLATVGVLITTGLTGMAAAWLFDLNIIQGLLIGAIVGSTDAAAVFSLLGGKGLNERVTASLEIESGSNDPMAVFLTVTLIDMLASGQTGLHWSLLTHLVREFGIGGVVGLGGGWLMLQMVNRINLATGLYPILVIAGGLFVFAVTNALHGSGFLAVYLCGLVIGNRPVRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLLPIALPALGLALWMILFARPLSVMVGLLPFKAFHGREKAFIAWVGLRGAVPIILAVFPLMAGLPHAQLYFNLAFFIVLVSLLVQGTSLPWVAKLLKVTVPPDPAPISRAALEVHVTSEWELFVYRLGAEKWCIGAALRELKMPEGTRIAALFRGQQLLHPSGSTVLEVGDLLCVIGHEHNLPALGKLFSQAPQRGLDLRFFGDFVLEGDAQLGAVSALYGLKLEGIDPDMPLSRFITQKVGGAPVVGDQVEWNNTIWTVAVMDGNKIGKVGVRFPEGSRPGPGLFL",
    "output": "K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNIKLIAIGKTDNKSLQTLIDDYTKRLSFYIKFDLEIIPDIKNVKNLSESQQKEKEGELILSKLSATDQLILLDENGKTFSSVGFSEELQKKMNSGVKTLVFVIGGPYGFSETIYKKAQGKVSLSLMTFSHQMVRLFFIEQLYRGFTILRNEPYHHQ",
    "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACATLLPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALIDCLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR",
    "output": "Involved in resistance toward heavy metals."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQYYKELARRLHTLQSKNEKEALEKQIDFLDKLVVEVDSLVHEQDLRPLLEFISPTESWFLLGTATIFYIKLLTHPDPESIDVVIKEAYVVRAHRILSIFQEQFIENVVKEINWEILAILISLSGIENGLVRNLSEFLSTSILSAVPRQKFLLYLLEKYQINLFHREERLTDQGRPVAFELPPDKFHSDQSKALLEPKWKTKNYLISHLIFWIIDQQSSSSIEVCWHRIIPSVLRILNDLSPNIKLQGIELVNRLLKITEREFLLYTGILKILKDDLLVFYTFIPPRFTIQTSVTLINASFATLVSLYPEENENLNSIMLNGINSVFQFAFDYPLILQAAFSQIMVLTDKMNVSYLPYLTLTLDELCRIIQNPQIIQIPSTLSFFLEILTKLLEIYSYRISAHHVELLMALVVCSRNYMRCNLQEHHNAIVQALQNLFTLIKLNITVEQLGDYNVILPLLEPLQIPL",
    "output": "Component of the tel2-tti1-tti2 (TTT) complex that stabilizes protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins . The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC) (By similarity). Component of the ASTRA complex involved in chromatin remodeling (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MILEHVLVLSAYLFFIGLYGLITSRNMVRALMCLELILNAVNMNFVTFSDFFDNSQLKGDIFCIFVIAIAAAEAAIGLAIVSSIYRNRKSTRINQSTLLNK",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADEEAGGTERMEISAELPQTPQRLASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSIFTPLEWYLFGEDPDICLEKLKHSGAFQLCGRVFKSGETTYSCRDCAIDPTCVLCMDCFQDSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCVNHEPGRAGTIKENSRCPLNEEVIVQARKIFPSVIKYVVEMTIWEEEKELPPELQIREKNERYYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAGAYAACQEAKEDIKSHSENVSQHPLHVEVLHSEIMAHQKFALRLGSWMNKIMSYSSDFRQIFCQACLREEPDSENPCLISRLMLWDAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQKEYISDDHDRSISITALSVQMFTVPTLARHLIEEQNVISVITETLLEVLPEYLDRNNKFNFQGYSQDKLGRVYAVICDLKYILISKPTIWTERLRMQFLEGFRSFLKILTCMQGMEEIRRQVGQHIEVDPDWEAAIAIQMQLKNILLMFQEWCACDEELLLVAYKECHKAVMRCSTSFISSSKTVVQSCGHSLETKSYRVSEDLVSIHLPLSRTLAGLHVRLSRLGAVSRLHEFVSFEDFQVEVLVEYPLRCLVLVAQVVAEMWRRNGLSLISQVFYYQDVKCREEMYDKDIIMLQIGASLMDPNKFLLLVLQRYELAEAFNKTISTKDQDLIKQYNTLIEEMLQVLIYIVGERYVPGVGNVTKEEVTMREIIHLLCIEPMPHSAIAKNLPENENNETGLENVINKVATFKKPGVSGHGVYELKDESLKDFNMYFYHYSKTQHSKAEHMQKKRRKQENKDEALPPPPPPEFCPAFSKVINLLNCDIMMYILRTVFERAIDTDSNLWTEGMLQMAFHILALGLLEEKQQLQKAPEEEVTFDFYHKASRLGSSAMNIQMLLEKLKGIPQLEGQKDMITWILQMFDTVKRLREKSCLIVATTSGSESIKNDEITHDKEKAERKRKAEAARLHRQKIMAQMSALQKNFIETHKLMYDNTSEMPGKEDSIMEEESTPAVSDYSRIALGPKRGPSVTEKEVLTCILCQEEQEVKIENNAMVLSACVQKSTALTQHRGKPIELSGEALDPLFMDPDLAYGTYTGSCGHVMHAVCWQKYFEAVQLSSQQRIHVDLFDLESGEYLCPLCKSLCNTVIPIIPLQPQKINSENADALAQLLTLARWIQTVLARISGYNIRHAKGENPIPIFFNQGMGDSTLEFHSILSFGVESSIKYSNSIKEMVILFATTIYRIGLKVPPDERDPRVPMLTWSTCAFTIQAIENLLGDEGKPLFGALQNRQHNGLKALMQFAVAQRITCPQVLIQKHLVRLLSVVLPNIKSEDTPCLLSIDLFHVLVGAVLAFPSLYWDDPVDLQPSSVSSSYNHLYLFHLITMAHMLQILLTVDTGLPLAQVQEDSEEAHSASSFFAEISQYTSGSIGCDIPGWYLWVSLKNGITPYLRCAALFFHYLLGVTPPEELHTNSAEGEYSALCSYLSLPTNLFLLFQEYWDTVRPLLQRWCADPALLNCLKQKNTVVRYPRKRNSLIELPDDYSCLLNQASHFRCPRSADDERKHPVLCLFCGAILCSQNICCQEIVNGEEVGACIFHALHCGAGVCIFLKIRECRVVLVEGKARGCAYPAPYLDEYGETDPGLKRGNPLHLSRERYRKLHLVWQQHCIIEEIARSQETNQMLFGFNWQLL",
    "output": "E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPRRREVAKRVILPDPKFNDRVVAKLVSVIMLDGKKSTAERALYGALDIVSQKAGEEPVKVLKKCLDNIKPMLGVKSRRVGGSTYQVPVEVRADRRVSLAMRWLVRYANERSEKTITDKLAGEILDAYNNRGAAVKKREDTHRMAEANRAFAHYRW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAGPVSLRELLMGASAWLGSESPGGPSAEGGGNAAGTPEPPWREDEICVVGIFGKTALRLNSEKFSLVNTVCDRQVFPLFHHQDPGDPGTGIKTKAVSVGEAGGAGDPGAAAGDSLRGGMATAEGNRAEPGPQDFSLLQAYYNQESKVLYLILTSICDNSQLLRACRALQSGEAGGGLSLPHAETHEFWKHQEKLQCLSLLYLFSVCHILLLVHPTCSFDITYDRVFRALDGLRQKVLPLLKTAIKDCPVGKDWKLNCRPCPPRLLFLFQLNGALKVEPPRSQDTAHPDKPKKHSPKRRLQHALEDQIYRIFRKSRVLTNQSINCLFTVPANQAFVYIVPGSQEEDPIGMLLDQLRSHCTVKDPESLLVPAPLSGPRRYQAMRQHSRQQLSFHIDSSTSSSSGQLVDFTLREFLWQHVELVLSKKGFDDSVGRNPQPSHFELPTYQKWISAAAKLYEVAIDGKEEDLGSPTGELTSKILSSIKVLEGFLDIDTKFSENRCQKALPMAHSAYQSNLPHNYTMTVHKNQLAQALRVYSQHARGPAFHKYAMQLHEDCYKFWSNGHQLCEERSLTDQHCVHKFHSLPKSGEKPEADRNPPVLYHNSRARSTGACNCGRKQAPRDDPFDIKAANYDFYQLLEEKCCGKLDHINFPVFEPSTPDPAPAKNEPSPAPPDSDAEKLKEKEPQTQGESTSLSLALSLGQSTDSLGTYPADPQAGGDNPEVHGQGEGKSEKRPNLVDRQASTVEYLPGMLHSNCPKGLLPKFSSWSLVKLGPAKSYNFHTGLDQQGFVPGTNYLMPWDIVIRTRAEDEGDLDTNSWPAPNKAIPGKRSAVVMGRGRRRDDIARAFVGFEYEDSRGRRFMCSGPDKVMKVMGSGPKESALKALNSDMPLYILSSSQGRGLKPHYAQLMRLFVVVPDAPLQIILMPQVQPGPPPCPVFYPEKQEITLPPDGLWVLRFPYAYVTERGPCFPPKENVQLMSYKVLRGVLKAVTQ",
    "output": "Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLYLSEENKSVSTPCPPDKIIFDAERGEYICSETGEVLEDKIIDQGPEWRAFTPEEKEKRSRVGGPLNNTIHDRGLSTLIDWKDKDAMGRTLDPKRRLEALRWRKWQIRARIQSSIDRNLAQAMNELERIGNLLNLPKSVKDEAALIYRKAVEKGLVRGRSIESVVAAAIYAACRRMKLARTLDEIAQYTKANRKEVARCYRLLLRELDVSVPVSDPKDYVTRIANLLGLSGRVMKTAAEIIDKAKGSGLTAGKDPAGLAAAAIYIASLLHDERRTQKEIAQVAGVTEVTVRNRYKELTQELKISIPTQ",
    "output": "Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRPIPSILGALGAFATLSAAAPLESTLYGPGASHARSMLGSSFGVPGNQTFDYVVIGGGTAGLAIASRLAEQGAGTVAVIEAGGFYELNNGNLSQIPANDAYYVGKDLDDWQPGVDWGFHTVPQAGAYGRASHYARGKCLGGSSARNYMAYQRGTKSSYQRWADMVGDQSYAWENFLPFFEKSLHFTPANDALRGANATVQYDPAVLGNGQGPLSVTYSHYVQSFATWAQKAFLEMGLAVRNCFQSGELLGQSFGMYTINATTMHRESSETSFLRRALAYPNFMVFQSTLAKRILFDGKKRAVAVQLDTQGYRYTLTARKEVVLSAGAFQSPQLLMVSGVGPAATLQQHGIPLVADRPGVGQNLQDHIIYAPSYRVDLITQSALLNATFEAQANRDYHERAAGIYANPTSDILAWEKIPEPKRSAWLSNTTRRALAQYPADWPEIEFLTMGGFFGYQNNYVRDNPSDGYNYASLAVSLCTPRSRGNVSIASADAAVPPLINPNWLTDPVDVELAVAAFKRARDFFGTSALKPVLIGDEYFPGERVATDAQIEDHVRKSFDTIFHASCTCAMGKREDQMAVVDSKARVIGVDALRVVDASAFPMLPPGHPQSTIYALAEKIACDISGAC",
    "output": "Patulin synthase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria (By similarity). PatE catalyzes the last step of the pathway which is the conversion of E-ascladiol to patulin (By similarity). The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units. The 6-methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (also known as 3-methylphenol). These first reactions occur in the cytosol. The intermediate m-cresol is then transported into the endoplasmic reticulum where the cytochrome P450 monooxygenase patH converts it to m-hydroxybenzyl alcohol, which is further converted to gentisyl alcohol by the cytochrome P450 monooxygenase patI. The oxidoreductases patJ and patO further convert gentisyl alcohol to isoepoxydon in the vacuole. PatN catalyzes then the transformation of isoepoxydon into phyllostine. The cluster protein patF is responsible for the conversion from phyllostine to neopatulin whereas the alcohol dehydrogenase patD converts neopatulin to E-ascladiol. The steps between isoepoxydon and E-ascladiol occur in the cytosol, and E-ascladiol is probably secreted to the extracellular space by one of the cluster-specific transporters patC or patM. Finally, the secreted patulin synthase patE catalyzes the conversion of E-ascladiol to patulin  (Probable)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFNPHALDVPAVIFDNGSGLCKAGLSGEIGPRHVISSVLGHCKFNVPLARLNQKYFVGQEALYKYEALHLHYPIERGLVTGWDDMEKLWKHLFERELGVKPSQQPVLMTEPSLNPREIREKLAEMMFETFSVPGFYLSNHAVAALYASACVTGLVVDSGDGVTCTVPIFEGYSLPHAVTKLCMAGRDITEHLTRLLFASGFNFPCILNKAVVNNIKEKLCYIALEPEKELRKSRGEVLGAYRLPDGHVIHFGDELYQVPEVLFAPDQLGIHSPGLSKMVSSSIMKCDTDIQNKLYADIVLSGGTTLLPGLEERLMKEVEQLASKGTPIKITASPDRCFSAWIGASIMTSMSSFKQMWVTSADFKEYGTSVVQRRCF",
    "output": "Negatively regulates the Hedgehog (SHH) signaling. Binds to the promoter of the SHH signaling mediator, GLI1, and inhibits its expression."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEMTPREIVSELDSYIIGQHKAKRAVSIALRNRWRRMQLDEALRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDSAIKMVRHQSIEKNRFRAEEMAEDRILDVLIPPAKNNWGQAEGTQEPSATRQAFRKKLREGQLDDKEIEIDLAASPVGVEIMAPPGMEEMTNQLQSMFQNLAGQKQKAHKVKIKDAFKLLIEEEAAKLVNPEELKQQAIEAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVASPSDLIPELQGRLPIRVELQALTTEDFERILTEPSASLTEQYKALMATEGVDISFTADGIRRIAEAAWQVNESTENIGARRLHTVMERLIEDVSYDASEMNGQSVIIDADYVRSHLDELVADEDLSRFIL",
    "output": "ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRVLLACLLVCALVVSDSDGSNEVHKESGESNCGCLNGGKCVTYKYFSNIQRCSCPKKFQGEHCEIDTSKTCYQGNGHSYRGKANRDLSGRPCLAWDSPTVLLKMYHAHRSDAIQLGLGKHNYCRNPDNQRRPWCYVQIGLKQFVQFCMVQDCSVGKSPSSPREKEEFQCGQKALRPRFKIVGGQVTNAENQPWFAAIYRRHRGGSITYLCGGSLISPCWVVSATHCFIDHPKKENYIVYLGQSRLNSDTRGEMQFEVEKLILHEDYSAESLAHHNDIALLKIRTSRGQCAQPSRSIQTICLPPEHEDAHSRTRCEITGFGKENPSDYRYSDELKMTFVSLVSHEVCQQPHYYGAEVTDKMLCAADPQWETDSCQGDSGGPLVCTIQGRLTLTGIVSWGRDCAMKYKPGVYTRVSKFLPWINTHTRGEINLVL",
    "output": "Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFNEITKSVTWNGQVLELSTGKIARQADGAVTVKMGNSVLLCTAVVANKAKEGIGFLPLTINYREMAYAAGKIPGGFFKHEGKASDREVLVSRLIDRPIRPLFHPAFVNETHVTCSVLSYDPETPVDILAIIGASAALSLSPAPYLEIVAASKVGLINGEFVLNPTLALLKTSQLDLVVAGTSDSVMMVESEAHLLSEEQMLEAVKFGFESFQPVIKIIKELAEEAKKPKLEMQALYPASLKKEIEKLFVKEIEQAFAIKSKQERSTNLDLIPEKVLTHFVSDIENKKYSNYQIESALKAIESDILRNEILEKNRRIDGRSTTDIRQIACEIGLLPSAHGSALFTRGETQSLVSTTFGTSLDEQIVDSLEGEYKERFMLNYIFPPYSVNEAMPMKAPSRREVGHGKLAWRAINPILPNKVQFPYSIRVVAETTESNGSSSMATVCGSSLALMYAGVPIKAPVAGIAMGLVKEGKNFAVLSDILGDEDYFGDMDFKVAGTSEGITALQMDIKISGVDFKIMKVALEQARLGRLHILEQMNKVISKPNNELSKNAPSTTTIKIDKDKIRDIIGPGGKIIKEICETSGAKIDISDDGTVSVYASDRDKLKVALDKIKAIVVEPEIGEIFNGTVVKVLDSGAFINYVGNKDGFVHISEVSGERIETVSSVLKQGDIVKVKLIGFDNKGKAKLTIKNADKDKSSNNTKPKTNVNNTNKDNSEPEQRRDSSKKRAWNEDNNAETAEVITERKYFN",
    "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAQKEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCVEMGFLRALTHSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLATICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLAVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQL",
    "output": "Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2 (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAKEVKFGDSARKKMLVGVNVLADAVKATLGPKGRNVVLEKSFGAPTITKDGVSVAKEIELKDRFENMGAQLVKDVASKANDEAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKATIAIVAELKNLAKPCTDSKAIAQVGTISANSDSSIGDIIAEAMERVGKEGVITVEEGSGLENELSVVEGMQFDRGYLSPYFINKPDTMVAELDSPLLLLVDKKISNIRELLPVLEAVAKAGRPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVISEEVGLSLETATLEHLGNAKRVVLNKENTTIIDGAGQQADIEARVAQIRKQVEDTTSDYDKEKLQERLAKLAGGVAVIKVGAGTEVEMKEKKARVEDALHATRAAVEEGVVPGGGVAWVRALQAISELKGENEDQNVGIALLRRAVEAPLRQIVTNAGGEPSVVVDKVKQGEGNYGFNAASDTYGDMIEMGILDPAKVTRSALQAAASIGSLMITTEAMIAEVAEDKAAGGMPDMGGMGGMGGMGGMGGMM",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSLAKSAANKLDWAKVISSLRITGSTATQLSSFKKRNDEARRQLLELQSQPTEVDFSHYRSVLKNTSVIDKIESYVKQYKPVKIDASKQLQVIESFEKHAMTNAKETESLVSKELKDLQSTLDNIQSARPFDELTVDDLTKIKPEIDAKVEEMVKKGKWDVPGYKDRFGNLNVM",
    "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFLLYEYDIFWAFLIISSVIPIFAFIISGVLAPISKGPEKLSSYESGIEPMGDAWLQFRICYYMFALVFVVFDVETVFLYPWAMSFDILGVSVFIEALIFVLILIVGSIYAWRKGALEWS",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSVDLATVKRVARLARIAVSDEEAERMTGELNGILGFVEQLSEVDVDGVEPMTSVMPMKMKKRDDIVADGDKADDIVANAPNSDRNFFLVPKVVE",
    "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLAAKSIAGPRAFKASAVRAAPKAGRRTVVVMARKNEVSESYAKALVELADEKGKLEAVHADVDAVAGLMKENAKLSALIMNPVVESDKKRAVLAKIAKEAGFQQYTINWLNLLVEKDRLSLVPEICECFEDLYCQMTDTQVATLRSAVKLEQEQQFLIAKKLQELTGSKNIKLKPVIDSSLIAGFVVEYGSSQIDLSVRGQIERVADQLTKEMTAKLS",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTYKRVLLKLSGEALMGEKPYGIDPAIVQSIAEDVSKVVGNNIQLAIVVGGGNIFRGLKGSADGMDRATADYVGMLATVMNAISLQDGLERVGVATRVQTAIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATKVDGVYNCDPNKFQDAKKYTNLSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISKAVAGEAIGSLIS",
    "output": "Catalyzes the reversible phosphorylation of UMP to UDP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKLIIGVITLFPQMFDALKSGVIGRALKQDRLTLSFWNPRDYATDPHRTVDDRPYGGGPGMVMKFEPLALALKAAKAQLGENTKVIHLTPQGKLLTQAIVREKIHASPLILLAGRYEGIDERLIEAEVDEEWSIGDYILSGGELPAMVLIDAMTRLLPGVLGHKDSASQDSFTAGLLDYLHYTRPEKIADRPVPSVLLSGDHEAISRWRLKQSLGRTWQRRQDLIKRRSLSENEQRLLDEFFEESS",
    "output": "Specifically methylates guanosine-37 in various tRNAs."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTQMTTADVPSMGRRQFMNLLTFGTVTGVALGALYPVAQYFTPYRAGGGGGGTNAKDELGNNVSASGWLSTHPVGDRSLVQGLKGDPTYLIVEGEDAITSYGINAICTHLGCVVPWNSGANKYMCPCHGSQYDSTGKVVRGPAPLSLAIAHVSIEDDQVLVSQWTETDFRTGTDPWWG",
    "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTAQIIDGKALAEELRQGFKARVEALTAKGHKPGLVVILVGADPASEVYVRNKVNGCLAIGMHSEKITYDATIDQATVLNKIAELNADPNIHGILVQLPLPKHFDEEAVLEAISAEKDVDGFHAENVGALAQGNPRFIPCTPYGVMKMFEKGNVDLTGKEAVVIGRSNIVGKPMALLLINAGATVTVCNSRTKDLKFHTSRADILVAAVGKPKFVTGDMVKPGAVVIDVGINRLPDGKLCGDVDFASCLEVAGQITPVPGGVGPMTITMLLANTIEAAERKAGL",
    "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTSMTPQEIVSELDKHIVGQSSAKRAVAIALRNRWRRQQVQGSLRQEITPKNILMIGPTGVGKTEIARRLAKLADAPFIKVEATKFTEVGYVGKDVDSIIRDLADMAVKQTRESEMKKVRARAEDAAEDRILDVLIPPPRGADGAEPAADGTTRQMFRKKLREGLLDDKDIEIDVTESRPHLEIMGPQGMEEMTEQLRSMFSQFGQDKRRTRKLKIAEAMKLLTDEEAGKLVNEEEIKTRALANAEQNGIVFIDEIDKVATRQETSGADVSRQGVQRDLLPLVEGTTVSTKYGMIKTDHILFIASGAFHLSRPSDLIPELQGRFPIRVELESLSVQDFEAILTQTHASLVKQYQALLATEDVTLAFVPQGITRLACIAFEVNERTENIGARRLSTVMERLLDEVSFDATRLSGQTVTIDEGYVDQRLQQLSLNEDLSRYIL",
    "output": "ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPVYEHLLPVNGAWRQDVTNWLSEDVPSFDFGGYVVGSDLKEANLYCKQDGMLCGVPFAQEVFNQCELQVEWLFKEGSFLEPSKNDSGKIVVAKITGPAKNILLAERTALNILSRSSGIATASHKIISLARSTGYKGTIAGTRKTTPGLRRLEKYSMLVGGCDTHRYDLSSMVMLKDNHIWATGSITNAVKNARAVCGFAVKIEVECLSEDEATEAIEAGADVIMLDNFKGDGLKMCAQSLKNKWNGKKHFLLECSGGLNLDNLEEYLCDDIDIYSTSSIHQGTPVIDFSLKLAH",
    "output": "Involved in the catabolism of quinolinic acid (QA)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSHAVKIYDTCIGCTQCVRACPLDVLEMVPWDGCKAGQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGDETSRSMGLSY",
    "output": "Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKKSKIVKNQRRAATVARYASRRTALKDIIRSPSSAPEQRSTAQRALARQPRDASPVRLRNRDAIDGRPRGHLRKFGLSRVRVRQLAHDGHLPGVRKASW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSVRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDALVLDVMMPRLDGLEVCRQLRGTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTKPEDAAESMAMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKTEADGEPRLIHTVRGVGYVLRETPP",
    "output": "Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region. MprB/MprA is involved in regulation of numerous stress-responsive genes, including up-regulation of two sigma factors, sigE and sigB as well as pepD and mprA, and repression of multiple genes from regulons associated with hypoxia, starvation and iron metabolism. The majority of genes regulated by MprB/MprA under a particular stress condition are different from those induced during normal growth, but several genes are commonly regulated under more than one condition."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKKVEYWVKIPFGPIHPGLEEPEKFIITLDGERIVNVDVKLGYNLRGVQWIGMRRNYVQIMYLAERMCGICSFSHNHTYVRAVEEMAGIEVPERAEYIRVIVGELERIHSHLLNLGVVGHDIGYDTVLHLTWLARERVMDVLEAVSGNRVNYSMVTIGGVRRDIGEKQKRLILDMIKYYREVLPQIEDVFLHDSTIEARLRDVAVVPKKLAIEMGAVGPTARGSGIKEDSRWSEQLGVYPDLGIKPVTPEDVTGEKARGDVYDRMAVRIGELWMSLDLLEHALDQMPEGKIKTFPKDNILVAKLKLLGDGEGIGRYEAPRGELVHYVRGQKGRDGPVRWKPREPTFPNLFTIAKALEGNELADLVVAIASIDPCLSCTDRVAIVKEGKKVVLTEKDLLKLSIEKTKEINPNVKGDPTPTGIGCSRGV",
    "output": "Alpha subunit of a hydrogen-evolving hydrogenase that utilizes protons both as a substrate for hydrogen production and proton translocation. Acts by coupling the redox reaction via ferredoxin and iron-sulfur (Fe-S) clusters to proton translocation across the membrane thereby conserving the redox energy in a proton gradient."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLNMVQSNPKGVEKTASKSEQDAWTLASARLLYDLPFNDLLFEAQNVHRANFDPNRVQLSKLLNIKTGGCPEDCGYCSQSAHHASGLKASKLMSLDTVLEEAQKAKDSGATRYCMGAAWRSPKPRDEPAIAEMVKQVKALGLETCMTLGMLSPDQAQTFAEAGLDYYNHNIDTSERFYPQVITTRSFDDRLETLAHVREAGIKVCSGGILGLGETEDDRIDMLVTLANLPTPPESVPINMLIPMPGSRLEKASPVDPIAFVRIIALARLMMPQSHVRLTAGRNSMSDEMQALCFFAGANSIFIGDTLLTAANPGEDRDTSLMRRLGLTADTLDNHA",
    "output": "Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MENRLINPVERVDDSVDNNIRPSTLAEYIGQPVVREQMEVFIEAARRRNEALDHTLIFGPPGLGKTTLANIIAREMGGNLRSTSGPVLERAGDLAAMLTNLEEGDVLFIDEIHRLSPVIEEILYPAMEDFQLDIMIGEGPAARSIKLDLPPFTLVAATTRAGLLTSPLRDRFGIVQRLEFYNIEDLTTIVSRSARLMNVVMTPEGAVEVARRSRGTPRIANRLLRRVRDYAQVKSNGEVTGEIADSALDMLAVDRRGLDHLDRRYIEMVHARFDNGPAGVEAIAAAMAEDRGTLEDVIEPYLIQQGYVLRTARGRVLTQMAIDQL",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTERKGMEEINREEFQEVVVNVGRVTKVVKGGRRFRFNALVVVGNKNGLVGFGLGKAKEVPDAIKKAVDDAFKNLIHVTIKGTTIAHDIEHKYNASRILLKPASEGTGVIAGGSTRPIVELAGIKDILTKSLGSNNPYNVVHATFDALAKIKA",
    "output": "With S4 and S12 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLQPARRKYRKEQKGRNTGISHSRGTAVSFGEFGLKAIGRGRITARQIEAARRAMTRHIKRGGRIWIRIFPDKPISQKPAEVRMGNGKGNPEYYVAEIQPGKMLYEMDGVDEALAREAFRLAAAKLPLLTTFVVRQVGQ",
    "output": "Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSKLSRKQQTQKRHKRLRRNLSGTESRPRLAVFRSNNHIYAQIIDDDAQNTICAASTLDKDLKASLKVNAGSCDASTAVGELVAKKALSKGIKQVIFDRGGNIYHGRVKALAEAARVAGLNF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPLLDSFTVDHTRMNAPAVRVAKHMSTPSGDAITVFDLRFCAPNKDILSERGIHTLEHLFAGFMREHLNGDGIEIIDISPMGCRTGFYMSLIGQPTESKVADSWLAAMVDVTNVIDQKDIPELNEYQCGTYEMHSLEQAQDIARMIIAAGVSVNQNDDLKLSDEILGNL",
    "output": "Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKIVKISPRGYCYGVVDAMVIARNAALDTSLPRPIYILGMIVHNKHVTDAFEEDGIITLDGPSRLDILDKIDSGTVIFTAHGVSPEVKQRAKEKGLTTIDATCPDVTKTHDLIEAKKAEGYHVIYIGKKNHPEPEGAVGIAPDIVHLIEKADDLKTLEIPTDKILVTNQTTMSQWDVQHLMEDIQKKFPTAEFHKEICLATQVRQEAVAKQADVADLTIVVGDPKSNNSNRLAQVSQEIAGTKAYRVADVSEIKLEWLQGVENVAVTAGASTPTPITKEVIAFLEQYDPMNPATWERVRKVPLQKILPRVKVKKEQ",
    "output": "Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MARIAYSTKIEGDNLARGKANELSISPKHSIEIADFIRHQRVNDALAYLADVVALKKAIPFRHFNRNVAHKRGLPGNWDAGRYPVKASKAYIRILESIKKNAEYTGLDTENLEIIHASANRGRAQKAYFPRAMGRASPKVRETVNIEIVVREVA",
    "output": "This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGFWLSLCGAVVLVAYLLGSFPTGYIAVKQLKGIDIREVGSGSTGATNVLRTLGKGPGAFVLGLDCLKGVLAIALVYYLFTFASNQNLIPTTVNIELWQPWLVTLAGIAAILGHSKSIFLGFTGGKSVATSLGILLAMNWQVGLATFGVFAVVVAISRIVSLSSIMGAIAVSIVMVFLQQPLPYILFGIAGGLYVILRHRSNIERLLAGTEPKIGQKLVTETEQSA",
    "output": "Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MPTVEVFNKEGKKVEDIELSEKVFGAKISESALHQVVVAQLANKRQGTQSAKTRTEVSGGGIKPWRQKGTGRARQGSIRAPQWIHGGVVFAPKPRDYRISIPKSMRRTAMLSALTSKVNDKEMIVLDELKIDAPKTKEIVKMLNAFEAKKALIVVAESDQNVYKSVRNIQGAAVIPANNLNVYDILKYDKFIVTKEAVSKIEEVYA",
    "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSRHVFLTGPPGVGKTTLIQKAIEVLQSSGLPVDGFYTQEVRQEGKRIGFDVVTLSGAQGPLSRVGSQPLPGKPECRVGQYVVNLDSFEQLALPVLRNAGSSCGPKHRVCIIDEIGKMELFSQPFIQAVRQMLSTPGIIVVGTIPVPKGKPLALVEEIRKRRDVKVFNVTRDNRNSLLPDIVAVVQSSRT",
    "output": "Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGGASACIPLCLLLATARMARPQTPERPVFTCGGILTGESGFIGSEGFPGMYPPNSKCTWKITVPEGKVVVLNFRFIDLENDNLCRYDFVDVYNGHANGQRIGRFCGTFRPGSLVASGNKMTVQMISDANTAGSGFMATYSAAAPDGKGDRYCGGRLEKPSGTFKTPNWPDRDYPVGVTCVWHIIAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDAKRIGKYCGDSPPVPIVSERNELLIQFLSDLSLTADGFIGHYKFRPKKFPTTTTTPVTTTLPVTTGLKPTVALCQQKCRRMGTLESNYCSSNFVLAGTVITTVTRGGSLHATVSIISIYREGNLAIQQAGKNMSVKLTVVCRQCPLLRRGLNYIIMGQVGEDGRGKIMPNSFVKMFKNKNQKPMNALKNKQC",
    "output": "Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLVPQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYASQETFGCLESAAPRDGSSLEDRPCNPL",
    "output": "Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2 . Recruits all ATG8 family members to infecting bacteria such as S.typhimurium . May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFLLHEYDIFWAFLIISSVIPILAFLISGVLAPISEGPEKLSSYESGIEPMGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSVFIEALIFVLILIVGLVYAWRKGALEWS",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLEEINYDTKLFGLIGKNIKYTLSPYIHNFSFTTLGINAVYLVFDLDEMKFNRIINGLLEIAEGLNVTIPYKEEVMKYLDNTDTYSTRIQAVNTIYKKSGYNTDYLAIKNLVRKKIGNMSGYECYVYGAGGAAKAAAFALSELGCSSISIVNRTNLRANELVELLNKNGYNASIKENCNSTSNIVVVNSTPNPSVVPENCIQKSELVIEFVYKPVETELIKNAKKYGIKYIDGLEILVNQAVEAEKIWFNKSVSDEKIIEYLYARKLVW",
    "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIVYSLLLLILYDFLPKVVTFDTVCIGLCHCVGNVVDCSSLDLSEIPTTIPNNTRILLLSDNEIESIDKSRLKGFYFLQTLDISNNIIRHIDFEFFYNLPNLKILNIRKNRLARIPRGSHELGHLEKLDLRSNLISTVTSEELSYLAAVRSVDLSRNLISYLPKPTTSAKVNIEKLDLASNSITDIGTDHFSSFNTLVTLKLARNHITTLNQFSFSRLRKLESLDLTRNMIREVRFLAFNQLPSLQNVSLARNDVYRLDDGMFYACEGLKHLNLSTNRVQAVTEGWMFGLTSLEVLDLSYNQIQSFHISSWSHTPKLKWLSLHSNRIQSLPSGSFRVLRQLEELILSANSIDSLHKFALVGMSSLHKLDLSSNTLAVCVEDGAVLYNTSMPFLRSLRFTNNQLRVIPKRAFERFPALEELDLTDNPIATIHPEAFEPLELKRLVMNSSSILCDCQISWLASWIYRLKLDKSSIIAKCSYPPPLADLYVVAIDTANLTCHNDSPRAKIVRQPVEVSTLIGEKARFTCNVYGASPLSIEWRVMENGQPRVLVQDSATFLSINRTAVVNGTFDERELAAAELLLDNVAMTDNSEYQCVARNRFGSDFSTHVKLQVYQAPKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPFPAAEARRLYVTPNDDHIYIMNVTKEDQGAYTCHATNVAGQTQASANLIVFENFFHYPESPDLSPMLIKKRDALKIDCSCDLISSRQRMVWKRQQQVILFLKKAKFSDNDQILTLTQTTFSDSGEYSCELWVDDTILMRKITMVKVVNEDEFVSSEATLTQRVQRIRAMASKLVDNIKSTGNGIYLMASCSAFGLMILGVITSICICIAKCSCNQNHVFNVLPVQV",
    "output": "Binds to the TGF-beta receptors sma-6 and daf-4, and enhances TGF-beta signaling activity in vitro. Has a role in regulation of body size."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSTNSFHDYVDLKSRTNTRQFSDDEEFTTPPKLSNFGSALLSHTEKTSASEILSSHNNDKIANRLEEMDRSSSRSHPPPSMGNLTSGHTSTSSHSTLFGRYLRNNHQTSMTTMNTSDIEINVGNSLDKSFERIRNLRQNMKEDITAKYAERRSKRFLISNRTTKLGPAKRAMTLTNIFDEDVPNSPNQPINARETVELPLEDSHQTNFKETKRNTDYDSIDFGDLNPIQYIKKHNLPTSDLPLISQIYFDKQREENRQAALRKHSSRELLYKSRSSSSSLSSNNLLANKDNSITSNNGSQPRRKVSTGSSSSKSSIEIRRALKENIDTSNNSNFNSPIHKIYKGISRNKDSDSEKREVLRNISINANHADNLLQQENKRLKRSLDDAITNENINSKNLEVFYHRPAPKPPVTKKVEIVEPAKSASLSNNRNIITVNDSQYEKIELLGRGGSSRVYKVKGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKRVIQLLDYEMGDGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIPFPEHTSNNEKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQPFMISGSIMEDLIRNAVRYGSEKPHISQDDLNDVVDTVLRKFADYKI",
    "output": "Involved in the regulation of the onset of mitosis. Involved in a pathway that coordinates cell proliferation and differentiation. Implicated in spindle pole body (SPD) duplication. Dual specificity kinase that can phosphorylate serine, threonine and tyrosine residues. Phosphorylates the SPC29 and SPC110 spindle pole body components."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQEKLKNDKLKIGKYEFDSRFILGSGKYSLELIKSAIEEAKAQIITLALRRANTGEIANILDYIPKNITLLPNTSGARNAEEALRIARLSRELGCGELIKIEVISDSRYLLPDNYETIKACELLAKEGFTPLPYMHADLYAARAMRDAGAAAIMPLAAPIGSNKGLCAKEFIQILLNEIDLPIIVDAGIGSPSQACEAMQMGVSAVMVNTAIAEAKDIALMARAFSLAVNAGRAAFLAGLASVSEAKASSPLTGFLRD",
    "output": "Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSDLTSTILFEHPLNEKMRTWLRMEFLLQQLESHRSLDNIANALTFFRSASDLIDVLERGEVRTDLLKELERQQQKLQQWADIPGVDVSLVDSLRNQLKSRAAVLMSAPRIGQSLKEDRLISVVRQRLSIPGGCCSFDLPTLHVWLHQPSEQRDQHINKLLASLAPLHQSLTIILDLIRQSCPLRSQISLNGFFQDNAGGADLLRLRLPLDPQLYPQISGHKTRYAIRFLALDSENGTVPARLSFELACC",
    "output": "Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAREYKIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTTYWKGRDGKTRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQAEKYNVPRMIFCNKMDKTGADFYRSVEMIKTRLGATAVVMQLPIGAETEFKGVIDLIEMNALIWRDESLGAQWDVVEIPEDMKAKAEEYREKLIETVVEIDEAATEAYLEGNLPDNDQIRALVRRGTIDVKFHPMFCGTAFKNKGVQPLLDAVVDYLPSPLDIPAIKGIDFKTDAEIERHADDSEPLSMLAFKIMNDPFVGSLTFARIYSGKLEKGASVMNTVKDKRERVGRMLQMHSNSREDIEEAFAGDIVALAGLKETTTGDTLCDPLKPVILERMEFPEPVIQIAIEPKTKGDQEKMGLALNRLAAEDPSFRVKTDQESGQTIIAGMGELHLDIIVDRMRREFKVEATVGAPQVAYRETITRLTEKDYTHKKQSGGTGQFARVKIVFEPNPEGDDFKFESKIVGGSVPKEYIPGVQKGIESVLSSGPLAGFPMLGVKATLIDGAFHDVDSSVLAFEIASRACFREAAREAGAQLLEPMMKVEVVTPEDYVGDVIGDLNSRRGQIQGQEARGIAVVINANVPLANMFKYVDNLRSMSQGRAQYTMTFDHYAPVPSNVAQEIQAKYSGQK",
    "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFHSLSVKNFILIDELEIEFTNGLCVITGETGAGKSILLDAILFCLGYKTSSAGIIKHGKDYAAVNIVFSLNDEIKNFLTQNFIELEESLLIKCVQKAEGRKNFFINNQVVNKAIMQQLATYLFELHGQNNNISLLEINTQRDILDSFGDLLELRMQLAKCYQAWQNIRNEIAEIALKQNSIEQEIDYLNFVTEELIKLNVQTGEEEQLTNIRKDLQNKDKDLQLIKDIFEQVNNPEINSSISKAEKLLAKQSQNEEFANISTNLEEAYNNLEEARQNLSNLLENFNKLDYNLEEIEERLFAIKAISRKYNVSADALKTFLEESLNRLNSLKGKIANQAELQVQEAKLSTEYYKLGKDLSGKRLAAAKRLEEVLHHELKQLKMEKATFHVNIAERKEAAAYGIDDIVFKASTNPGMSPEAINKIASGGELSRFMLALKTSLFNKMVKPAIIFDEIDVGIGGEVADKVGERLKKLSSATQVIVITHQPQVAGKADLHIKIEKTQLEKETKVTVKALNLAERQQELARMISGKAITEASLKAAKELLCHPVA",
    "output": "May be involved in recombinational repair of damaged DNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPRSLKKGPFIDDHLLKKVETQNDKGTKNVIKTWSRRSTIIPEMLGHTIAVHDGRKHVPVFVTEAMVGHKLGEFALTRTFKGHEKDDRKSRRR",
    "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAVCPHEWLLYCRPGFEKDLSAELADKTAHAGQGGYPIAARDSGHVRFVLDPETPANEVHRALPLEALVFARQSLVAFPPLEALPRDDRLSAIVDLVVASGWSFESIWQETPDTNEEKALAGLMKALRKPLESTLKKRGALRRKAGGRRLHLFWTAGDRVQLAMSFPGNRAEHLGGIPRLKFPREAPSRSTLKLEEAWHVFVPREAWPTRLSDSMQAADLGAAPGGWTYQLVRKGMYVYAIDNGPMDDALMASGQVEHLCEDGFVWQPPMRLDWLVCDIVDKPMRVIDMVERWLVAPWCHEAIFNLKLPMKKRWDEVSRCLERLASSLDQAGIRARIRCRHLYHDREEVTVHVCLLD",
    "output": "Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKEEEEIGKPAKPKAKKDVAPGRLIDTYAAQCDNCHKWRVIDSQEEYEDIRSKMLEDPFNCQKKQGMSCEEPADIDYDSSRTWVIDKPGLPKTPKGFKRSLVLRKDYSKMDTYYFTPTGKKLRSRNEIAAFVEANPEFRNAPLGDFNFTVPKVMEDTVPPDPKLGSPFPSTTTTTSEKSSVKQSHN",
    "output": "Transcriptional regulator that binds CpG, CpNpN and CpNpG (N is A, T, or C) islands in promoters regardless the DNA methylation status. Plays probably a role in gene silencing."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRIAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF",
    "output": "Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQADVPGTQRKPEGLQAAFTSVFPIVSHNGFARLEFVSYALSSPAFNIKECQQRGLTYCSALRAKVRLVILDKESPNKPVVKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMDEGAQLEFVPERLRGEVARFDITDRDGKVIVQKDKRINAKHIRDLEAAKTKFISVPEDYLLGRVLAKNVVDGDTGEVIASANDEVTESVLEKLREAGIKEIQTLYTNDLDQGPYISSTLRVDETTDKTAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEEAYDLSKVGRMKFNRRVGRDEITGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKVVDSKVTDQIDYLSAIEEGRYMIAQANAAIDENGQLVDELVSSREAGETMMVTPDRIQYMDVAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPVVGTGIERTCAVDSGTTVQAFRGGVVDYVDAGRIVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPIVKMGDKVSRGDVLADGASTDLGELALGQNMLIAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGDAFQRLARMLVGKVANGGPKKLAKGTKIDQAYLEDLDHYHWFDIRLADDEAAAQLEAIKNSIEEKRHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPLGVPSRMNVGQVLEVHLGWAAKGLGWRIGEMLQRQAKIEEMRSFLTKIYNDSGRKEDLESFTDDEILELAKNLREGVPFATPVFDGATEEEMGKMLDLAFPDDIAEQLGMNPSKNQVRLYDGRTGEMFERRVTLGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLDRN",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKRKMLKRLLTSAFACMFIANGLITTTVRAVGPKTGEENQVLVPNLNPTPENLEVVGDGFKITSSINLVGEEEADENAVNALREFLTANNIEINSENDPNSTTLIIGEVDDDIPELDEALNGTTAENLKEEGYALVSNDGKIAIEGKDGDGTFYGVQTFKQLVKESNIPEVNITDYPTVSARGIVEGFYGTPWTHQDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPESEMQRMQELINASAENKVDFVFGISPGIDIRFDGDAGEEDFNHLITKAESLYDMGVRSFAIYWDDIQDKSAAKHAQVLNRFNEEFVKAKGDVKPLITVPTEYDTGAMVSNGQPRAYTRIFAETVDPSIEVMWTGPGVVTNEIPLSDAQLISGIYNRNMAVWWNYPVTDYFKGKLALGPMHGLDKGLNQYVDFFTVNPMEHAELSKISIHTAADYSWNMDNYDYDKAWNRAIDMLYGDLAEDMKVFANHSTRMDNKTWAKSGREDAPELRAKMDELWNKLSSKEDASALIEELYGEFARMEEACNNLKANLPEVALEECSRQLDELITLAQGDKASLDMIVAQLNEDTEAYESAKEIAQNKLNTALSSFAVISEKVAQSFIQEALSFDLTLINPRTVKITASSEETSGENAPASFASDGDMNTFWHSKWSSPAHEGPHHLTLELDNVYEINKVKYAPRQDSKNGRITGYKVSVSLDGENFTEVKTGTLEDNAAIKFIEFDSVDAKYVRLDVTDSVSDQANGRGKFATAAEVNVHGKLKENAEVTGSVSLEALEEVQVGENLEVGVGIDELVNAEAFAYDFTLNYDENAFEYVEAISDDGVFVNAKKIEDGKVRVLVSSLTGEPLPAKEVLAKVVLRAEAKAEGSNLSVTNSSVGDGEGLVHEIAGTEKTVNIIEGTSPEIVVNPVRDFKASEINKKNVTVTWTEPETTEGLEGYILYKDGKKVAEIGKDETSYTFKKLNRHTIYNFKIAAKYSNGEVSSKESLTLRTAR",
    "output": "Binds carbohydrates . Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins. Can bind and deglycosylate O-glycosylated peptides from mammals."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIIKIHNQTSFCITPFKSLLIKMFLPIKEKKLMHLIFVTNEKIQELNSFYRQKNYPTDVLSFPNDLTFFAGLEDNSLGDVFISFSKAQVQAQTAKHSLEREIAFLAVHGFLHLKGYQHRTEEEFQIMLALQEKILQNVGLNLDKTT",
    "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARRPEADAPPKKQAGPRINEEIRAAKVLLIDENGEKQGVMPLAAALDAAREASMDLVEVSAGQETPVVKILDYGKLRFEERKKKAAARKKQKSSELKEIKIRPNIDTHDYEVKARAIARFFEEGDKVKITLRFRGREMAHQHLGMELLEKVKKDFEETAKVELEPKLEGKQMTMVLAPR",
    "output": "IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHLLIPAAGSGRRFGADRNKLLLPLLGQPVLAWTLQAADQAQSITWIGIIGQPGDRADIEALVDQLQLATPVSWIQGGRERQESVFNGLRSLPSGAQQVLIHDGARCLATPTLFDRCSAALQTCPAFVAAVPVKDTIKQVAADGTIAATPDRSTLWAAQTPQGFTVESLLRCHRQGLEQQLAVTDDAALLEAFGLPVQIVEGEETNLKVTTPADLAIAELILKQRQFTAAIA",
    "output": "Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNANWNFDNSYARLPERFFTRIYPTPVSDPKLVVLNHSLAKELGLNAEVLASEEGVAVFAGNRVPEGAEPLAQAYAGHQFGYFNMLGDGRAILLGEHVTPSGERVDIQLKGSGRTPYSRGGDGRAALGPMLREYIISEAMHALGIPTTRSLAVVTTGEVVMRETELPGAILTRVAASHLRVGTFQYAGRFLSKEELQALADYAIKRHYPNGEHASNRYVFLLEEVMKKQAALVAKWQLVGFIHGVMNTDNMTISGETIDYGPCAFMDVYDPETVFSSIDTQGRYAYGNQPYIAGWNIARFAESLLPLLHDEEEKAIEIAQKVIEQFPALYETYWLQGMRAKLGLWTEEAEDKKLIGELLHLMYTHRLDYTNTFRSLTLEEWHFCEQELRDWYTRWQQRIARQDMTKEEVYECMRQNNPAIIPRNYRVEEALAAAVEHGDDTVMERLLHVLSDPYAYMEEQEEYAKTPEPSDRPYRTFCGT",
    "output": "Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAARNATPTPQNGRDASRLSFAKITDTLTVPDLLALQTESFDWLVGSDAWKRRVEEGTAQGRTDLALNSGLEEIFEEISPIEDLGETMQLGFTNPYLEEQKYSIDECKERGKTYSAPLYVEAEFMNHLTGEIKTQTVFMGDFPLMTEKGTFIINGTERVVVSQLVRSPGVYFERQQEKTSDKDIYSARVIPSRGAWLEFEIDKRDQVGVRIDRKRKQSVTVFLKALGLTSEQILEEFKGVASIELTLEKDSILTKEEALKDIYRKLRPGEQVAAEAARALLDNFYFNPKRYDLAKVGRYKINRKLGIDKQLTDSVLTVEDILATIKYLVSLHANETKMNGTRDGKPVELRLDVDDIDHFGNRRIRAVGELIQNQVRTGLSRMERVVRERMTTQDIEAITPQTLINVRPVVAAIKEFFGTSQLSQFMDQNNPLAGLTHKRRLSALGPGGLSRERAGVEVRDVHPSHYGRMCPIETPEGPNIGLIGSLASFARINSFGFIETPYRRVVDGVVTDTIDYLTASEEDEFLVAQANAPLTKDFRFAEDRVLVRPKGGEVELVAKENVHYMDVSPRQMVSVATSLIPFLEHDDANRALMGANMQRQAVPLLRSESPLVGTGMEGYAAIDAGDVLTADASGVVQEVSAEVVTIQLDEGGTQTYYLRKFDRSNQGTSYNHRVLVSAGDRIEAGEVIADGPATENGELALGKNLLVAFMPWEGHNFEDAIILSQNLVKDDTLSSIHIEEYEVDARDTKLGKEEITRDLPNVSPELLADLDERGIIRIGAEVRPGDILVGKVTPKGETELSAEERLLRAIFNEKSREVRDTSLKVPHGEQGTIIGVKVFDSQDGDDELGSGVNQRVVVFIAQKRKITEGDKLAGRHGNKGVISKILPVEDMPFLADGTPVDVILNPLGIPGRMNFGQVLETHLGWIAKQGWEVEGKPKWAERLPDHARQAPAGTKVATPVFDGALEEEIAGLLDSTTVTRDGDRLIGSSGKTRLFDGRSGEPFPEPVSVGYMYILKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWALEAYGAAYALQELLTIKSDDILGRVKVYEAIVKGENIQEPGIPESFKVLIKEMQSLCLNVEVLSADGQAVSLRDTDDEVFRAAEELGINISTRFESSSIDDI",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNKDHEEQLEINEVSQKNKYKSIIESLLFMSGEPINIKDLATILNCKQDKVSSLLNEMNNSYVGKDRGIKILIHNRAVQLVTKPENSIYVEKLLKTNVRQSLSQAALETLSIIAYKQPITRVAIDEIRGVKSDRAIYTLLEKNIIKECGRLDVPGKPILYGTTEEFLKFFGLDSIEAIPNLEDLLKEFSKEEN",
    "output": "Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNINLDTAKDTLCKNILIYGYCKYENKGCAFSHNRQQPAQQQQATNTSNNSTSVITPNSANSTASSADLSSKKKFNLNTPSFQPSVSNLSNKFSTLSPKLKEIPVFKPENGVSEPDTVDSPTTQRPFTSKRFNVSTPSFTPTNFDFANNSNADGNRGGASTPIGISSAPLVQNQQQQQQQQQQQQKQPLAVPSPLASGAQPPTMQHRILSMGVSQSSPSTNPYFANNLDMSAPTPGSETPGPVLPGSAGAAAAAANQPMYPLQYHLYAPAPPPRLTIPLQPYETNSQAMFIPNDLREYLHKKNEASLQSLSHSNLPEHVNQYHSLVPIDKSYEPVSKLWLGKNSLIFKCLDNIDGNLYVMRKIEPCNEIINEKPFKTIKRWKSIKNANIVGLQDAFTTMAFNGNQSGNTSLCIIYDYYPNSISLLEHHKKGLRVEPVNEALLWNYLIQLINAIMAIHEKGLSASSTIDLSKIIVTNKNRIKLSSVGISDILEFKDDETNQDIKIRQLQDIQKVGKVLMELAILLLPVNMRQSNNIYNSLKASTNLSEEIINNLQELNDLDTASGEFDLNEFSQRLTPKMFNIIDSLQNSSDFIEGQLTSELENARLFRLMTKLNYLIHDNSNSENDKIIKLFLNYVYNCYDSNNKKVINLNKVLINLNKLDCGIDEKILLVNNDECIIISYKELKEIIDTKFRLMRE",
    "output": "Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLDREGFRPNVGIILLNARNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLLPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMLGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRADKPRGPRLPRYPRVIAAQPAETLTIVDTSVVCSEVEVEASTLDEMPPRVIVGK",
    "output": "Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "WCSTCLDLACGASRECYDPCFKAFGRAHGKCMNNKCRCYT",
    "output": "Inhibits high conductance calcium-activated potassium channels (By similarity). Reversibly inhibits Shaker B potassium channels."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNLQDVILTPIVTEKSQDLETIGANSKKGTRMVKYTVKVHIDANKTLIKEAFKKIFKVTPSSVNVQVYRGKIKRFRNMPAARPHWKKAIVTFRDGASIDFAKEA",
    "output": "One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MENKNQKHNNEFHEKNQQSQKDNNNVKKENLHEDQSDLNDANFDDGGKKNKLKNDIKKLNHLVDSLKNENNNKQAKIESLERQINLLNENFKSEVIKKASEAQTKLDEKIKEFQAKYETELKHAKKYALKSSAIELIDIVSNFELAVNSKVTNPEIANYLKGFQMFANMFKNYFQQNGITEIPVNLNDDFNAEVMQAFETQKAPNTQPNKVIKIIKKGYKLHDIVLVPATVIVSE",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTSTFRHVALIGKYHAPSASAPSENASNALERIADFLRRQGCEVVLDTQSALHAGLTDYPTLDVDGLGRHCDLGLVVGGDGTMLGVSRHLAQYGTPLIGVNQGRLGFVTDIALEDFEATLTPMLQGEYEEDLRPLMCARVIRDGQCVFEALAMNDVVVNRGGTSGMVELRIEVGGRFVSNQRADGLIVATPTGSTAYALSAGGPMMHPSIPAWVMAPIAPHNLSNRPIVLSDANEVTIEVVAGRDVSANFDMQSLASLQHGDRILVSRAHHSVRFLHPKGWNYFATLRKKLGWNEGGA",
    "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLSHAELKQGFHYFMMGWHLITQKGLRRFVIMPILLNIVLLSGLFWLFITQIEKMIGMLMLSIPDWLSWLSSILLIFAILMILVLFYFVFTTLSGFIAAPFNGLLAEKVEKMLTGENLVEGSVWDFMKDIPRMLGREWQKLVYSLPKLIILFLLGFVPVLGQSVIPIIVTLFTAWMMAIQYCDYPFDNHKVPFFVMKAELAEKRALSLSFGGLVMLCTFIPLVNLVVIPVAVCGATAMWVTHFRDHLAMKPLNQEGVSRVSTVSIVK",
    "output": "High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSLTRHEIREKAFQALFALNANPDADENQLFQQLLNPEETDAVEIPAYLSTLVTGVREHQVELDAQIQPYLSQKWSLDRLAKTDLIILRIAFFELQFVDDVPTKVAVNEAIELTKAFSDDRSRKFVSGVLGKVVKNQAN",
    "output": "Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTSFKLVKYIPRIKKKKSGLRKLARKVPTDRLLKFERIFKAQKRINMSVFKAQRVLDEIRWRYYEETVMILNLMPYRASYPILKLVYSASANATHYRNFDKANLFITKAEVSRSTIMKKFRPRARGRSFPIKKNMCHITIILNIVKK",
    "output": "This protein binds specifically to 23S rRNA.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPSSLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAKWFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGVKALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFLMKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFPNSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNKNFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYGKEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGVSSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPSTYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYADIQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDEYAKAREKWLKEKEESNKKAQEELAKHVK",
    "output": "Part of the binding-protein-dependent transport system for oligopeptides; probably an oligopeptide binding protein."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDKQLNDAPCGFLALSEEGSIIAANRTLIKILDYEPEQVIGQHMNMMLTIPAQLFCQLYFFPLLKLEHHIEEIYISLKARDGEEIPVLINAIARHDSGASVFDCVLIPMRKRNEYENELLIARNEAQEALLAKQKANAELEIALETLKAKQEELLEINKQNQQFKLNTKRELELARKIQKNSLTEPIVNDQVQIDSYYNASSELSGDLYGYYQIDEHRYGIIILDVMGHGISSALITMSLHPLFQRQITQGLSPVKVMKELDRHLHSLFQNDEEARHYCTAIYLEIDIARQRIDYVNAGHPPALWQDDSGTQHLLHATSPPIGMFEDLEFQSSSLSYTEDGRLLLYTDGVMDPTASCYLFDLLKDHPDSPIADLKEKILTSLQHQKEAHHKSDDECFILVDVK",
    "output": "Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to energy stress."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSEDYLDRDVSPALTVGEADIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGATPDHILLSGPPGLGKTSLAMIIAAELGSSLRMTSGPALERAGDLAVMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVIVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTAHMDFYEPTELEGVLARAAGILGIELGVEAGAEIARRSRGTPRIANRLLRRVRDFAEVRADGVITRDVAKAALAVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEATTVEEVCEPFLVRAGMVARTPRGRVATAQAWTYLCMTPPVGVTGLSQPGLFES",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKRDYYEVLGVAKNASDEDLKKAYRKLAMKYHPDRNPDSKEAEEKFKEAKEAYEVLGDEQKRAAYDRYGHAGVDPNAAGMGGGMGGGMGGGFADAFGDIFGEIFGAGRRGGGGPQVYRGADLKYALEITLEQAASGFDTEIRVPSWENCDTCHGSGAKAGTSPKTCRTCGGSGAVRMQQGFFSVQQTCPTCHGTGKEITDPCPSCDGVGRTRRNKTLQVKIPAGIDDGMRIRSSGNGEPGINGGPPGDLYVEIHIKQHKIFQRDGDDLHCELTIPFTTAALGGELQVPTLGGKAEISIPEGTQSGKTFRLRAKGIRGVRGSYPGDLYCHVVVETPVRLSDEQKAILRQFEASLNDGGDRHSPQSKSWTDRVKEFFS",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPIKSRIRAIPDYPKKGIMFRDITTLIKDPVGFRLVIDGLTQRYLENGVDFDVVVGVEARGFILGSALAYTLGKGFVPVRKPGKLPADVVSQEYELEYGTDKVEIHLDAILPGTRVLLVDDLLATGGTALAAAALVEKVGGVVAEMAFIVNLPDIGGERKILDKGYRVFSLTEFEGE",
    "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAREREQRHEREDRDNTFVDKLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATESAKRALIRVPLREGRTLHHDVHGHHGAGKVILRAAPAGTGIIAGGPMRAVFETLGMHDVVAKSFGSSNPYNMVRATFDALKNQDSPRSVAARRGIKVSQLQSRRRVEDAEATD",
    "output": "With S4 and S12 plays an important role in translational accuracy.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPEGPEIRRAADNLEAAIKGKPLTDVWFAFAQLKPYESQLTGQIITRIETRGKALLTHFSNGLTLYSHNQLYGVWRVIDTGEIPQTTRILRVRLQTADKTILLYSASDIEMLTAEQLTTHPFLQRVGPDVLDARLTPEEVKARLLSPRFRNRQFSGLLLDQAFLAGLGNYLRVEILWQVGLTGQHKAKDLNEAQLNALSHALLDIPRLSYTTRGQADENKHHGALFRFKVFHRDGEACERCGGIIEKTTLSSRPFYWCPHCQK",
    "output": "Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVTIWLGSGRMLVLASASPRRAMLLEAEGFSFIRVEADVSEVLPQGISPESAVKGLALRKAQAGLNRWLNHGGSREDIILGADTIVVLNQQILGKPRDEEEAEAMLTALSGQTHYVYTGVALVNGAGRQECGAVCTAVFFRSLTHEEILEYIATGEPVDKAGAYGIQGLGGHLVDHYEGSLSNVIGLPMEYVKERLSVWGMGLGDIALHEVKDGLPSVKGST",
    "output": "Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGDAGGHSHHHQHGFQPQLLSFGGVGHHHHLHQFTAQPQPPAASHTRGRGGGGEIVPATTTPRSRGGGGGGGGEIVAVQGGHIVRSTGRKDRHSKVCTARGPRDRRVRLSAHTAIQFYDVQDRLGYDRPSKAVDWLIKNAKDAIDKLDVLPAWQPTAGGAGAGNAAAPPSSSTHPDSAENSDDQAQAITVAHTAFDFAGGGSGGTSFLPPSLDSDAIADTIKSFFPMGGTAGGEASSSTTAAQSSAMGFQSYTPDLLSRTGSQSQELRLSLQSLPDPMFHHQQHRHGGGGGGGNGTTQQALFSGAANYSFGGGAMWATEQQAQNQRMLPWNVPDPGGGGGAAYLFNVSQQAAHMQAAAAALGGHQSQFFFQRGPLQSSNQPSERGWPETVEADNQMSHHQGGLSPSVSAAIGFAAPGIGFSGFRLPARIQGDEEHNGGGGGNGDKPPPPSSVSSASHH",
    "output": "Transcription activator. Binds the promoter core sequence 5'-GGNCC-3'."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLAFIQGELAEVKENYVVVDNNGMGYEIFIPHTVHSYLPAIGDKVKFHTYLQVREDGMALFGFLNREDLAMFKLLITVNGIGPKGAIGILSAISTDDLRFAVLAEDVKAISKAPGIGTKTASKLILELKDKFKLEDAFEATFQSNQVISTGGKGNNDGIREEAIQALVALGYSATDALKAVKAVEITSNMTSEDVLKFSLRNF",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPFLGQDWRSPGWSWIKTEDGWKRCESCSQKLERENNRCNISHSIILNSEDGEIFNNEEHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFALQKHYPAKEQYGDTLHFCRHCSILFWKDYHLALLFKDSGHPCTAADPDSCFTPVSPQHFIDLFKF",
    "output": "Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSITKEQILDAISEMSVMNIVELISDMEKKFGVSSIIPSSSTSTQNIETAEAKTEFDVLLKSIGGNKVSVIKAVRSATGLGLKEAKDLVESAPTIIKERITQDAAESLKKILNETGAEVEIK",
    "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSRFISTFRSSSAQLSIVLAVILATGCSQPTTLQEIREEGVLHVITRVAPSIYYQDREQDTGYDYELARLFANELGVELRVRVADDNSEILSVLSRNYAHVGLAGLTQRPDFDNQYRSVPIGVSAQSVIVYHKEVPAPESLEDLASETIHMLADSNHEHLIADPANEAGPIIQKHPGLDAAGLLARVESGEFGYAAVASNELDLNHVFFPKVYEAFALNEPSDLVWLFPAAQDDTLVNAAEAFMERVNNNGTMAQLAERFYGHLDRLNYVGARTFMHHVENRLPRYQSLFKDYAQESGMDWRLLAAIGYQESHWRPNAVSPTGVRGLMMLTRTTANYIGINNRLDAEESIEGGARYFRMVHGRIPDRIPEPDRTWFALASYNVGFGHLEDARRLAESAGKDPDRWMDVKEFLPLLAQKEWYTKTRFGYARGHEPVVYVQNIRRYYDVLVRITEPDAPSASGLEDQLAWLGDNEAGPEAPAKESQPDLRADLPPELRLIPPTL",
    "output": "Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGQDQTKQQIEKGLQLYQSNQTEKALQVWMKVLEKGSDLVGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARGLEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSLFQKALESFEKALRYAHNNDDTMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNDYGKGWSLKYRAMSQYHMAVAYRLLGHLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVHVLLGVAKCWMARKVQDKALDAIEKAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRTHVVRFHECVEETELYCGLCGESIGERNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV",
    "output": "Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIALIQRVSEAAVRVDGEVVGQIDKGLLVLLGVEKDDDEAKAKRLMERVTTYRVFEDSEGKMNLNVQQVDGKVLVVSQFTLPADTKKGTRAGFSRGAHPADAERLYDYFSDLCQQVLPTERGRFAADMKVSLINDGPVTFWLQV",
    "output": "An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLTHTLGFPRMGAHRELKKNLESYWKGAIGQEKLMASGRELRLRHWRLQQQAGIDLVPVGDFSYYDHMLDMVAMLGAVPPRFGWQGESVDLDTYFYMARGSSGHRTTTAMEMTKWFDTNYHYIVPEFYPGQRFRLARNRLFEELAEACIEGIQAKPVLPGPMTFIALGKEMVAGFDRWSHLDAVVEVYEEIVSRVAAKCSWIQLDEPILATDVPGPIRLRVRDVYRRLAAVAGPCRLMVATYFGALQENLDLALSLPVDGLHVDLVRAPGQLEKVLPCLPENMVLSLGLIDGRNVWRSNLRQAISTAQDAVVARGSDRVMIAPSCSLLHVPVDLAGEAVLDPRIRSWLAFARQKCQEVNVVRLALDGEDVTEVLQANDTAMENRRKSALVHRDAVRRRMADISPDMYCRRSSFEERKKQQAWLRLPTLPTTTIGSFPQVAGVRSARRSFKQGRISEEQYRAEMQRYIREAIAQQEALGLDVLVHGEPERNDMVEYFGEQLAGFCFTENGWVQGYGSRCVKPPIIYGDVERLKPMTMEWTTYAQQQTNRPLKGMLTGPVTMLCWSFVRDDQPRSATCKQIALAIRDEVQDLEQAGIKIIQVDEAALREGLPLRKSAWREYLGWAVDAFRLTASGVADSTQIHTHMCYSEFNHIAEWIAKMDADVISIEASRSNMELLGVLESFTYPNDIGPGVYDIHSPRVPSVAEMVELLRKASEVIPLERLWVNPDCGLKTRAWPETLASLRNMVAAAQKLRFFARG",
    "output": "Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNPVYSPGSSGVPYANAKGIGYPAGFPMGYAAAAPAYSPNMYAGPNPAFQPGYTPGTPYKVSCSPTSGTVPPYSSSPNPYQTAVYPVRSAYPQQNPYAQQGAYYTQPLYAAPPHVIHHTTVVQPNGMPATMYPAPIPQPRGNGVAMGMVAGTTMAMSAGTLLTSHYPTPVAPHQVTMPTYRPPGTPTYSYVPPQW",
    "output": "Inhibitor of neuronal axonal outgrowth."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MIEAITHGAEWFIGLFQKGGEVFVGMVTGILPLLISLLVIMNALIVFVGQRRIEKLAQKCAGNPVTRYLVLPFIGTFVFCNPMTHSLGKFLPEKYKPSYYAAASYSCHSMNGLFPHINPGELFVYLGIANGLTTLGVPLGPLAVSYLLVGLITNFFRGWVTDLTTSVFEKKMGIKLDKSVHL",
    "output": "The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. The enzyme II complex composed of SrlA, SrlB and SrlE is involved in glucitol/sorbitol transport."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGGYKGIKADGGKVDQAKQLAAKTAKDIEACQKQTQQLAEYIEGSDWEGQFANKVKDVLLIMAKFQEELVQPIADHQKAIDNLSQNLAKYDTLSIKQGLDRVNP",
    "output": "Virulence factor that is important for the establishment of infection in the host. EsxB is required for EsxA synthesis as well as secretion (By similarity). Mediates together with EsxA the release of S.aureus from the host cell. Inhibits also host cytokine production and thus modulates dendritic cell-mediated immunity (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVKKVLLINGPNLNLLGTREPEKYGTTTLKDIEMEAHQQVAKHQDAELFTYQNNTEGFIIDRIQEAKQQGVGFIIINAGAYTHTSVGIRDALLGTAIPFIEVHITNVHQREPFRHHSYLSDKAIAVIAGLGVYGYTAAIEYALNY",
    "output": "Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTQMTDAKNNIITKEMEFVAKEENIAVEKIRKWVAKGFVVIPKNIHRNTKPVGIGDNLKTKVNVNLGTSTDCIDIDMEIRKAIISEEYGADAIMDLSTGGELPEIRKQILKNTTLPVGTVPMYEIGIESKNKYGRVIDFDEDIIFNTIERQAKEGVDFMTLHCGITKHTIDTLNNDDRIMGVVSRGGAYITAYIMHHQKENPLYSQFDYLLEMLKEHDVTLSLGDGMRPGCLCDHTDRPQIQELIVLGELVDRCREAGVQVMVEGPGHVPLNNVETNMKIQKTLCKNAPFYVLGPLPTDLAMGYDHITSAIGGALAAYSGANFLCYVTPAEHVRLMNEDDVREGLIASKIAAQVADVAKGNKQAWAKEKEMAIARKNHDWEKQFELSIDSDKPKKMREELPPKEEDACSVCGEYCALLMVEEAGKR",
    "output": "Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTETINTAAQFPSFEKPTVQFNEKGWGPCELPDTFKDVPYQPFSKNDRLGKICDWTNTSNNDKKYQNKYASSFGTGNQYSYYHEEDETTFHLVDTARVQKPPHQRGRFRNMRNSRSGRGRNARGGLNTHGMTTLSGKNVKARDPRHGRGMGKKFGHRGPPPKMRESSVAVRADWASIEEMDFPRLIKLSLPNIKEGVDIVTCGTLEYYDKTYDRINVKNEKPLQKIDRIVHTVTTTDDPVIRRLSKTVGNVFATDAILATIMCSTRSNYSWDIVIEKVGDKIFMDKRDHTEFDLLTVNESSVEPPTDDDSSCNSPRNLAIEATFINHNFSQQVLKTGDQEPKFKFEESNPFISEDEDIQVASVGYRYKKWELGSDIVLVARCEHDGVLQTPSGEAQFMTIKALNEWDSKLANGVEWRQKLDTQRGAVLANELRNNACKLAKWTVQAVLAGSDQLKLGYVSRINPRDHSRHVILGTQQFKPHEFATQINLSMDNAWGILRCIIDLVMKQKDGKYLIMKDPNKPIIRLYDIPDNTFDSDDSDDGEGDDEGFQQVYNYAHNKI",
    "output": "mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MASPAPPEHAEEGCPAPAAEEQAPPSPPPPQASPAERQQQEEEAQEAGAAEGAGLQVEEAAGRAAAAVTWLLGEPVLWLGCRADELLSWKRPLRSLLGFVAANLLFWFLALTPWRVYHLISVMILGRVIMQIIKDMVLSRTRGAQLWRSLSESWEVINSKPDERPRLSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGSYIPGVILSYLLLLCAFLCPLFKCNDIGQKIYSKIKSVLLKLDFGIGEYINQKKRERSEADKEKSHKDDSELDFSALCPKISLTVAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSDDLDRPSEEVFSRDLSDFPSLENGMGTNDEDELSLGLPTELKRKKEQLDSGHRPSKETQSAAGLTLPLNSDQTFHLMSNLAGDVITAAVTAAIKDQLEGVQQALSQAAPIPEEDTDTEEGDDFELLDQSELDQIESELGLTQDQEAEAQQNKKSSGFLSNLLGGH",
    "output": "Endoplasmic reticulum (ER)-anchored autophagy regulator which mediates ER delivery into lysosomes through sequestration into autophagosomes . Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins . Active under basal conditions . Required for collagen quality control in a LIR motif-dependent manner (By similarity). Required for long-term survival of nociceptive and autonomic ganglion neurons .; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "ADVPGNYPLDTRGYSYYCTILGENEFCKKICKVHGVSYGYCYNSGCWCEYLEAKDVSVWNAAKNYCKNPVGK",
    "output": "Binds to sodium channels (Nav) and affects the channel activation process."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDMQGDGEDNHMDGDKGARRGRKPGSGGRKNGGMGTKSKDKKLSGTDSEQEDESEDTDTDGEEETSQPPPQASHPSAHFQSPPTPFLPFASTLPLPPAPPGPSAPDEEDEEDYDS",
    "output": "The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MATSQRKILVTSALPYANGPIHLGHMLEYIQTDIWSRYQKLRGHECHYICADDAHGTPIMLKAQQLGMAPEEMIAQVNKEHQQDFADFNIAFDNYHSTHSEENRVLASDIYLKLRANGYIKSKSISQLFDPEKSMFLPDRFVKGTCPKCKSPDQYGDNCDACGATYSPTELINPKSAVSGATPVMKDTEHFFFDLPAFEDMLKEWTRSGALQTEMANKLDEWFEQGLQQWDITRDAPYFGFEIPDAPGKYFYVWLDAPIGYMGSFKNLCDKRPELSFDEFWAKDSKAEVYHFIGKDIVYFHSLFWPAMLHGSGYRQPNSVYAHGYVTVNGAKMSKSKGTFIKARTYLDHLDPEYLRYYYAAKLSSRIDDLDLNLEDFAQRVNSDLVGKLVNLASRTAGFITKRFDGKLAKIADTTLTDAFLAKQEQIAEFYETREYGKAMREIMALADIANGFVADAAPWQLVKQDDQQEVAHQVCSNALNLFRILVTYLKPVLPRLAQDVEAFFQQTLTWDGLGQDMAGHEIAPFKAMMQRVEFDKVEAMVADSKENLQATSEPEAPKGPLATDPISDTINFDDFAKIDLRIARIVKAEHVAEADKLLKLQLDIGGETRQVFAGIKSAYSPEDLEGKLTVMVANLAPRKMRFGMSEGMVLAAGPGGSDLWILEPHEGAQPGMRVK",
    "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFAKNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYRGYYHVLHGLISPMNGMGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVLKPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL",
    "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLEKYKNSKKLSRDLPQINDRIKFPKVRVIDDEGEQLGIFAPEAAIQLATKQGLDLVLVSDKSDPPVCRILDYGKYKFTQEKRAREAKKKQHNSSIKEVKMRYKIEEHDYKVRINQASKFLQSGDKVKATITFRGREIQHSNLAINLLNKMAADLVTIAEIQQAPSRDGRNVIMLLSPKKVN",
    "output": "IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTASYSPSISVPLVGLVFPAITMVLSFIYIERDEIV",
    "output": "May help in the organization of the PsaL subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAAPVKKTGSKKSKKNVPNGVVHIQSTFNNTIVSITDTSGHVISWSSAGASGFKGARKGTPFAAQTAAEAAAKRALDQGMRQIKVLVRGPGSGRETAIRALQVAGLEITLIRDVTPLPHNGCRRPKRRRV",
    "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSSVKTPALEELVPGSEEKPKGRSPLSWGSLFGHRSEKIVFAKSDGGTDENVLTVTITETTVIESDLGVWSSRALLYLTLWFFFSFCTLFLNKYILSLLGGEPSMLGAVQMLSTTVIGCVKTLVPCCLYQHKARLSYPPNFLMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNVLGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVAMLVPARVFFTDVPVIGRSGKSFSYNQDVVLLLLTDGVLFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSVIVFGNKITSLSAVGTALVTVGVLLYNKARQHQQEALQSLAAATGRAPDDTVEPLLPQDPRQHP",
    "output": "Putative transporter."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAYSACFLHQSALASSAARSSSSSSSQRHVSLSKPVQIICKAQQSHEDDNSAVSRRLALTLLVGAAAVGSKVSPADAAYGEAANVFGKPKTNTDFLPYNGDGFKVQVPAKWNPSKEIEYPGQVLRFEDNFDATSNLNVMVTPTDKKSITDYGSPEEFLSQVNYLLGKQAYFGETASEGGFDNNAVATANILESSSQEVGGKPYYYLSVLTRTADGDEGGKHQLITATVNGGKLYICKAQAGDKRWFKGARKFVESAATSFSVA",
    "output": "May be involved in the regulation of photosystem II."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MISNAIARRYAKALVQLGAEEDAVDRFGAELGQFAALLEGNADIDSVLKSPAYRIEAKREILKDVLAKLSLSGTVSNFLQVLLDRGRISFLPQIAHSYAAFADELSGVIRPVLTSAFPLEDAQVESMKGALVKATGKKVQLSVQVEPSLIGGVITKIGDKVFDGSVRTQLNRIQDILQKG",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVHLPLSRSRSGRRAVPDLSRYQQFYEADAADGYSTGSGLSSAAASVASLRRPGVGMGRTQSLTGYGRTRSLGAARPSYLGAPPRTYSMSSQRRANSLRSNNGFGPPAVAAGNTITVKTTETKDLQGRTRTVTRQTVKHINGVRYVETTTTMTMPDGEYPDDFYGFEGDFTAKQTSSGHVYQNARGAPDISDIAEEESLEEYLDARDTAPALRIQLRAPPRVQQQRQLQRQRRLSDTNFPARRSAKSSPARQSSEEPPATTKPHRIRFDETPQIVGIDPPTQKKAPKKQMTEQEMYMHALDAARKKVYGEISQPALEAKQPHRSTMSKRMTLRDEATLAANTPPERSRPAKREVRKKEGHSHHNFLSVLRRDSSPKRHAVQPSERVHNKEKTLEMTPDSSSASSYEEARFEHSDEMYNKALEVAKKKYHLTQENSTRDNGTTECPRTPMTSLMSTNVSSDTAESTLLGTPVYSSNAPFDRSPQPSSGCETGNTTPKSIPRRPSFLDKLVRFSQEKYGYRPRRSISSQGHKAEHEHVFTDDIPPLPDIPLVDPMQVKPKDVPLPTVEPALGPTDVSPARVADPESNIETPRTLAPARSSISSSPRRSSPPQAFQELVPLQSTQSETTGDLADALALGDNSLDLLPGRVSEISPKTSFEHFVLAPEVPETDEKPAAAPAVAAEAPLSNPPSVVVVPSATSSVPAAQGAAPGVAVTEGPSLGGPAAPVRALHATKTAAAPAKKRSFFHKLFKKY",
    "output": "May be involved in the control of meiotic sister-chromatid recombination."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALPDGKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSTDGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRIAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETAYKVTDVIDVTIAEVRMETRSIIARPVA",
    "output": "Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKTFGKKVVLIGDGSVGSSYAFAMVTQGVADEFVIIDIAKDKVKADVQDLNHGTVHSPSPVDVKAGEYEDCKDADLVVITAGAPQKPGETRLQLVEKNTKIMKSIVKSVMDSGFDGYFLIAANPVDILTRFVKEYTGLPAERVIGSGTVLDSARLQYLISQELGVAPSSVDASIIGEHGDTELAVWSQANVAGISVYDTLKEQTGSEAKAEEIYVNTRDAAYEIIQAKGSTYYGIALALMRISKAILNNENNVLNVSIQLDGQYGGHKGVYLGVPTLVNQHGAVKIYEMPLSAEEQALFDKSVKTLEDTFDSIKYLLED",
    "output": "Catalyzes the conversion of lactate to pyruvate (Potential). Contributes to S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells, despite playing a secondary role in this resistance mechanism (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MQALMEDSKIKEEIWIEKYRPVRLNQVAGQDETIERLKSYVATKNLPHLLFSGPPGVGKTASAVSIAREIFGEDLWRENFTELNASDERGIDIVRNKIKNFAKTAPIGGAPFKIIFLDEADALTADAQSALRRTMERFSSNCRFILSCNYSSKIIEPIQSRCAVYRFRRLSDEAIKERLEYIAGDQGLSITEGGYEALIYVAQGDMRKAVNSLQAAAFIDTDKSISRETIYRTTATANPEEIKNLIETALRGNFRIARKELNRLLYEEGLSGEDIVGQIYRVVSEMDNLMVLDLGLTERDIVALVDVIGETDFRLTEGASEKIQLEALLAHFALSREN",
    "output": "Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "AIDYDEDEDGRPKVHVDAR",
    "output": "Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTKQVEIFTDGSCLGNPGPGGYGAILRYKQHEKTFSAGYYLTTNNRMELMAAIVALEALTSPCEVTLSTDSQYVRQGITQWIHNWKKRGWKTADRKPVRNVDLWQRLDLAIQSHTIQWEWVKGHAGHPENERCDELARQGANSPTLDDTGYNPD",
    "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAILGALGLGDIGKHFLDTDNQFKNIDSKFFLAEIKKMLDKKQYSISNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR",
    "output": "Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVMMIIIYTEPEISLFPLQDRSEELSSNVENGSCNSNEGINPETSSHWIENVVKVRKPYTVTKQREKWSEEEHDRFLEAIKLYGRGWRQIQEHIGTKTAVQIRSHAQKFFSKMAQEADSRSEGSVKAIVIPPPRPKRKPAHPYPRKSPVPYTQSPPPNLSAMEKGTKSPTSVLSSFGSEDQNNYTTSKQPFKDDSDIGSTPISSITLFGKIVLVAEESHKPSSYNDDDLKQMTCQENHYSGMLVDTNLSLGVWETFCTGSNAFGSVTEASENLEKSAEPISSSWKRLSSLEKQGSCNPVNASGFRPYKRCLSEREVTSSLTLVASDEKKSQRARIC",
    "output": "Probable transcription factor."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHTTLLSNSMRGAALCTRVSSTTLNPVTLQTSAIYQTISLKNQTRPSSTSTVRFLKASPTLRTSSARPQAQIATSCINAKNTISVRSNSTTSTSAREEAAKLDWNSYFKLRASRRRYTLASSIVSSAVSTVVGVQVLSSQNLENLGAQVMGLDPFVVLGMATAACGAVGWLVGPFLGNAVWGLVNRSYKKAFLVKEKEFFDRIKRYRVDPSSNSMTNPVPDYYGEKIGSVQGYRQWLKDQRAYNRKRRSFIK",
    "output": "Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLVNFKLMLQKAKLGKYAIPHININNYEWAKAVLTAANQANSPIIVSVSEGALKYMSGYSVVIPLVKGLIESLSVKVPVTLHLDHGSYDACIQALQAGFSSVMFDGSHLPFEENFNKSKKLIEIAQKTNASVELEVGTIGGEEDGVIGQGELANVDECKQIASLKPDALAAGIGNIHGIYPKNWKGLNFPLIETISKITNLPLVLHGGSGILENDVKKAISLGICKLNINTECQLAFAHEIRKYIESNKDLDLNKKGYDPRKLLKEPTQAIVDTCLEKIDLCGSRNKA",
    "output": "Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MASLKRFQTLVPLDHKQGTLFEIIGEPKLPKWFHVECLEDPKRLYVEPRLLEIMFGKDGEHIPHLESMLHTLIHVNVWGPERRAEIWIFGPPPFRRDVDRMLTDLAHYCRMKLMEIEALEAGVERRRMAAHKAATQPAPVKVREAAPRPASVKVPETATQPAPVKVREAAPQPAPVQEVREAAPQQASVQEEVREAATEQAPVQEVREAATEQAPVQEVSEAATEQAPVQEVNEAATEQASVQAVREAATRPAPGKVRKAATQPAPVQVCQEATQLAPVKVREAATQPASGKVREAATQLAPVKVRKAATQLAPVKVHEAATQPAPGKVSDAATQSASVQVREAATQLSPVEATDTSQLAQVKADEAFAQHTSGEAHQVANGQSPIEVCETATGQHSLDVSRALSQKCPEVFEWETQSCLDGSYVIVQPPRDAWESFIIL",
    "output": "As part of the OOEP-KHDC3 scaffold, recruits BLM and TRIM25 to DNA replication forks, thereby promoting the ubiquitination of BLM by TRIM25, enhancing BLM retainment at replication forks and therefore promoting stalled replication fork restart . Regulates homologous recombination-mediated DNA repair via recruitment of RAD51 to sites of DNA double-strand breaks, and sustainment of PARP1 activity, which in turn modulates downstream ATM or ATR activation . Activation of ATM or ATR in response to DNA double-strand breaks may be cell-type specific . Its role in DNA double-strand break repair is independent of its role in restarting stalled replication forks . As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics . Required for maintenance of euploidy during cleavage-stage embryogenesis . Required for the formation of F-actin cytoplasmic lattices in oocytes which in turn are responsible for symmetric division of zygotes via the regulation of mitotic spindle formation and positioning . Ensures proper spindle assembly by regulating the localization of AURKA via RHOA signaling and of PLK1 via a RHOA-independent process . Required for the localization of MAD2L1 to kinetochores to enable spindle assembly checkpoint function . Promotes neural stem cell neurogenesis and neuronal differentiation in the hippocampus . May regulate normal development of learning, memory and anxiety . Capable of binding RNA ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSQTHLSTKKFADFPLKPEILAALNENGFEFCTPIQALSLPILLNAKDIAGQAQTGTGKTMAFLVATFNHLLNVAAPESRKATEPRAIIMAPTRELAIQIAKDAKLLAAHTGLKVGIVYGGESYETQRAVLDKGVDILIGTTGRIIDYVRQGVISLSHIQAVVLDEADRMFDLGFIKDIRFLFRRMPDAKSRLNMLFSATLSMKVQELAYDHMNDPEKVEIEPLEKTSKNIKEEIFYPSMEDKMRLLLSLIEEDWPDKAIVFSNTKHSCEKLWSYLEGDGHRVGLLTGDVPQKKRIRILEQFTSGEIDVLVATDVAARGLHISDVSHVYNYDLPDDCEDYVHRIGRTGRAGQKGISISFACEEYALNLPEIETYINHSIPVSNYDKDALLDDIPPPARIHRKPPTSRTRDGGSKGAHRSGGNTSRPPRHRTRRP",
    "output": "DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNYLPAPPPGTTPLRVLSIAGSDSGGGAGIQADMRTMTVLGVHACTAVTAVTIQNTLGVEGFHEIPAEIVASQIKAVVTDIGIQSAKTGMLASSSIIAAVAETWLRLELTTPLVVDPVCASMHGDPLLTGEAMDSLRDRLFPLATVVTPNLDEVRLLVGIDVVDTESQRAAAMALHALGPQWALVKGGHLRSSDRSCDLLYGGSSAGVAFHEFDAPRVQTGNDHGGGDTLAAAVSCALAHGYTVPDAVGFGKRWVTECLRDAYPLGRGHGPVSPLFQRT",
    "output": "Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSIEVANESGIDVSEAELVSVARFVIAKMDVNPCAELSMLLLDTAAMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPSMLGDIVLCPEFAAEQAAAAGHSLGHELALLTIHGVLHLLGYDHAEPDEEKEMFALQDRLLEEWVADQVEAYQHDRQDEKDRRLLDKSRYFDL",
    "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLKPISALNDNYIWVYGRENCPVIVVDITEIEPLLPFLRENKFAVEAVLLTHKHDDHVGGVAAFKRYFPDVPVYGPQECADKGATRIVNEGEIVTANYRIRVIPTGGHTAQHVSYVTDGCLFCGDTLFSAGCGRVFTGNYGQMYDSVQRLKTLPDDTLVCPAHEYTLANLAFAESVMKDKSAVKNQRVLVEKKRAENRPSVPTTLGLEKQINPFLIAENPAQFETWRKAKDQF",
    "output": "Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNKDINIAAIIKNEIENFEGKIQNHDIGKVIIVGDGVALVSGIEKVKFGELVEFENNVLGIALNLEQDLIGVVIMASENSVFQGSIVRRTKSVISITVGDQLLGRVVNALGIPIDGKAELDNSLKSAIFTNAPSIMDRKSVDRGLKTGILAIDSLVPIGKGQRELIIGDRQTGKTTIAIDAILNQKGKNVYCVYVAIGQKNSSVAQIVSLLEKKGAFEYTTVILAGASELSPLQYLAPYSGAAIAEYWMNKKKDVLIIYDDLSKHAIAYRTLSLLLRRPPGREAFPGDIFYQHSYLLERSAQLSNDKGGGSITALPIIETQAGDISAYIPTNVISITDGQIFLRDSLFNSGQKPAIDIGLSVSRVGSAAQTNLMKWASSSLKLNLAQYNELKAFAQFGSDLGPSSQLILDRGNKIYEILKQENQYPLTERQQIMLLILIRENLIDSLEQKSIPLFKSAFLKYCDSEPKFRDKIEKMDYNRVLEPNNLAGILKDITDFIEKFNLGNVF",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MHLNPSEISELIKSRIEGLEATAEVRTQGTVVSVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVVLGEYEHITEGDTVKCTGRILEVPVGEELIGRVVNALGQPIDGKGPITTKHSEPIEKIAPGVVWRQSVNQPVQTGLKAIDAMVPIGRGQRELIIGDRQTGKTAVAVDAIINQKGENMICIYVAIGQKASSISNVVRKLEEHGAMEYTIVVAATASESAAMQFIAPYSGCTMGEYFRDTGRDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSAAYVEKETNGAVKGKTGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLESDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLGGGVRLALAQYRELAAFAQFASDLDEATRKQLERGKMVTELMKQPQYSTLSVSEMALTLFAVNKGYLDDVEVSRALAFESALRGFIRSKYGAILDKIETTKDLDAETEKELDAAIQDFKKNGTY",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLVKADMTKDIAQVMAEVGRKAKAAAAPLSIATSEQKNKALNAAADAILEARADILEANRLDLANAEKNGMAASFVDRLTLNEARIDAIAEGIRAIATLPDPVGEVIAEWDRPNGLHIERVRTPLGVIGVIYESRPNVTADAGALCLKAGNAVILRGGSDSAHSSAAIHKALEAANLPADAIQIVPVTDRAAVGEMLKGLGGAIDVIVPRGGKSLVARVQSEARVPVFAHLEGICHLYIDKSADLDMARRIALDAKMRRTGICGAAETLLVDRAVASTHLAPILGDLAAGGCEIRGSAEVLALYPAAKPATEEDWSTEYLDAIISVALVDGISGAIDHINRYSSHHTEAIVAEDAQTVARFFNEIDSAILLHNASTQFADGGEFGMGAEIGIATGKMHARGPVGVEQLTSFKYRVRGSGQVRG",
    "output": "Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSLTRLHIETFRNISSAQLHPSDGLNLIYGQNGSGKTSVLEAIYFLGMGRSFRSHLSQRVIQHQDDKLTLFANLSLGEQESKIGLRRFRSGETEVKINGDKIKRLSTLAETLPIQVITPESFSLLFEGPKSRRQFIDWGAFHSDKSFHSAWANVKRILKQRNQLLKNQVSYSQIQFWDKELVRYSELVTLIRKEYVDSLNEQLKGIIVEFLPQVEVKVSFTRGWDSKTDFGQLLETQYLRDVAAGNTGSGPHKADLRLRVGTLPVQDALSRGQLKLLVCALRIAQGKLLKQQTDKNSIYLVDDLPSELDAKHRQLLLQQLMDTGAQIFVTAIDPAAIVDSLTTPPSKMFHVEQGCVTVIDKPTRE",
    "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNERVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEVDGDDDAEEMEAKAED",
    "output": "Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. EIF2S1/eIF-2-alpha is a key component of the integrated stress response (ISR), required for adaptation to various stress: phosphorylation by metabolic-stress sensing protein kinases (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2) in response to stress converts EIF2S1/eIF-2-alpha in a global protein synthesis inhibitor, leading to a attenuation of cap-dependent translation, while concomitantly initiating the preferential translation of ISR-specific mRNAs, such as the transcriptional activators ATF4 and QRICH1, and hence allowing ATF4- and QRICH1-mediated reprogramming."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSNVDRAEIAKFEALAHRWWDRESEFKPLHDINPLRVNWIDERANLAGKKVLDVGCGGGILSEAMALRGATVTGIDMGEAPLAVAQLHQLESGVSVEYRQITAEDLAEEMPEQFDVVTCLEMLEHVPDPSSVIRACHRMVKPGGQVFFSTINRNPKAYLFAVVGAEYILNLLPRGTHDFKKFIRPSELGAWSRDAGLQVKDIIGLTYNPLTKHYKLASDVDVNYMIQTLREA",
    "output": "O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MARIAGVDLPREKRIEVSLQYIYGIGKTSAKLILERANVSPVTRTKDLTDDEVRRIRETIEQNVKVEGDLRREISLNVKRLMDLGCYRGLRHRKGLPVRGQRTHTNARTRKGPKKGLVRKAAAPAPKA",
    "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAMNFVTFNQDYSYLAVATSKGFRIFTTDPFAKSYETKEGHIAIIEMLFSTSLVALILSPRRLQITNTKRQSTICELTFPTTVLAVKLNRKRLVIVLEDQIYLYDIQTMKLLYTIQTSPNPNAICALSPSSDNCYLAYPLPQKAPPSSFTPPSHAPPGNTHVSPTSGEVLIFDSLKLEAINVIEAHRSPLACITLNSDGTLLATASDKGTIIRVFSVPDGHKLYQFRRGSMPSRIFSMSFNTTSTLLCVSSSTETIHLFKLSQQTSSSRDTSPSSSTPAGRDRAFSQSSLGHSPDRSDVSGEPDSSEFPARKHNGTLMGIIRRTSQNVGSTVAAKVGGYLPKGVSEMWEPARDFAWIKLPKPSQNAGGSGNNGPLRSVVAMSNNTPQVMVITSDGNFYVFSIDLSKGGEGTLTKQYS",
    "output": "The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct atg9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKILVDENMPYVEPLFGDLGDIIPVNGRTLTAEQVRDADVLLVRSVTKVNAELLSGNNKLKFVGSATIGTDHVDLAYLAERNIPFSNAPGCNATAVGEFAFIAMLELAQRFNSPLKGKVVGIVGAGNTGTATAKCLQAYGIKVLLNDPIKAAEGDPRSFVSLDTITAQADIISLHVPITRTGEHKTKHLFDEARLKALKPNTWLVNCCRGDVIDNQALIKVKRQRDDLKLVLDVWEGEPTPLPELVPLAEFATPHIAGYSLEGKARGTFMLYQKLCQLLNITADKSLLDLLPTFNIKAVELATAPNEKALLQLARFVYDLRDDDKMFRNTFLNENGFDTMRKNHQHRREFSALALAYDGQSEVDWLSNLGFSGVGQ",
    "output": "Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAGWELLKLLLDDVQEHSTLIGKVWLTVLFIFRIFILSVAGESVWTDEQSDFICNTQQPGCTNVCYDQAFPISHVRYWVLQFLFVSTPTLIYLGHMVYLSKKEEKERQKENESRILVANEAQTEVHSSATKKIRIQGPLMCTYTTSVVFKSIFEAGFLLGQWYIYGFVMSPIFVCERIPCKHKVECFVSRPMEKTIFIIFMLVVSLISLLLNLMELIHLSFKCFQHGIKEGATCSPTGIPFNGAGNRMPPQEYTNPPSSNQDIDLPSYNKMSGGHNWSRIQMEQQVNGLVKPKCQCDCWSQSAISVVVSGAPGIISNMDAVKSNHQTSSKQQYV",
    "output": "One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALGDYEYEEIENRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILDADDEEDQNLKLLGEDEMDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDELDEDEEVFEDEEDFND",
    "output": "Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGNKRIKAMMILVVMIMMVFSWRICEADSLRRYSSSSRPQRFFKVRRPNPRNHHHQNQGFNGDDYPPESFSGFLPKTLPIPHSAPSRKHNVYGLQRTNSRSSYFWTHAHLS",
    "output": "May be involved in floral abscission."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAYNQEDSKRLSDKYKKEGHFDKLKREILSNPWNNTEENSESFEQALRKRVASTVKEMVNEDEELIFKNRGLTSALIESQLVKDNYLKLGSKMEGDNGDGEKKFDLDVYVRSKLQDPKLLEMIKGQLQETLNSYEEEANGST",
    "output": "The COMPASS (Set1C) complex specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKHVTTREKRRARIRRKISGTELRPRLTIYKSLKHMYAQLVDDVAGKTLVSVATTSKSLKGELGDEDKTAAAKKVGEALAKAAKAKGIEQVVFDRNGFDYHGRVEAVAAAAREAGLKF",
    "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MITIKKGLDLPIAGTPAQVIHNGNTVNEVATLGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVVFTAPASGTVVTINRGEKRVLQSVVIKVEGDEQITFTRYEAAQLASLSAEQVKQNLIESGLWTAFRTRPFSKVPALDAIPSSIFVNAMDTNPLAADPEVVLKEYETDFKDGLTVLTRLFNGQKPVYLCKDADSNIPLSPAIEGITIKSFSGVHPAGLVGTHIHFVDPVGATKQVWHLNYQDVIAIGKLFTTGELFTDRIISLAGPQVKNPRLVRTRLGANLSQLTANELNAGENRVISGSVLSGATAAGPVDYLGRYALQVSVLAEGREKELFGWIMPGSDKFSITRTVLGHFGKKLFNFTTAVHGGERAMVPIGAYERVMPLDIIPTLLLRDLAAGDTDSAQNLGCLELDEEDLALCTYVCPGKNNYGPMLRAALEKIEKEG",
    "output": "NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEAHGVNPNAIKAMNEVNIDITNQTSDIIDANILNRADLVVTLCSHADAVCPSTPPHVNRVHWGFDDPAGKEWPEFQRVRDEIGERIKRFSETGE",
    "output": "Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKKIKILLDTMGYENTLEHVIKAAKDFYYQHEDDLEIILVGNEQLIKPLLDNDWRLFPIVHTEVSIEQNDTILSARKKQNSSMHLALRYLKDKQANGMLTAGNSAVFVYNAYATIGLLEHIKKPAFMPFVPTIDGGVTNLLDVGASIDLDGRDLFNFAIMANTIAKMRTPNPRVGVLNIGTEDHKGLPYHQEANELLKTSNLNYVGFVEPKTILEREVDVLVADGFSGNIALKTMEGVGKTISNFLKNEYKKPKNLFAALLSKPIFKKMKKAFDYKEHAGAFVLGLDGILVKTHGSADYQQFMSALKILYETIKADVLNEIKKDLNNYYGQ",
    "output": "Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEASEDLEPEQDYDEALGRLEPPRRIGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAQEQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVLGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRKSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKDAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLRIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSMKKPPSITPIFLESPPKEEGGPGAAEQT",
    "output": "Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDIEETIYKYALTNAIEHGNKCQVGSVIGMVMSKNPEMRKDPKTVSQLAGKLVAKVNNLTPEEQQKEVESLGGLEQHTKKEEKPKGLPELKNTEDKKVTLRFAPNPSGPLHIGHARAAILNKLYQEKYNGKLILRIEDTDPKRVEPDAYDAIPQDIKWLGIEPDEIYTQSDRLEIYYEYAQKAIEIGAAYMCKCDGGEFKKLKDNCQPCPCRSHTIEENMELWNNFENMEEGEAVLRIKTDINHKNPAIRDWVAMRIVNQEHPRLGNKYKIYPMMNFSVTVDDHLMGMTHVLRGKDHLANSEKQTYLYKHFGWDVPEFIHYGRLKMDDVELSTSKAREGIENKTYTGWDDPRLGTIRAIARRGIKKEVLYDLIEEIGTKQADATISWKKIYGLNRNIIEENTNRYFFIPNAVKVDVENLPSSKTNMTVERELHYNKPEKGFRNLTFNGSVYIPEDDYKHAQDKNIPLRLMDLINIKIEEDKVIYDSETLEDAQAQHARIIQWAPVETSISATVVMPDNTHVTGYIECDASNLEVDDMVQLERFGFARVDKINDNEITFYYTHN",
    "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEDETVALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPINPKSNREKMTQIFFETFNAPAFYVSIQAVLSLYASGRVTGIVLDSGDGVTHVVPIYSGFSLPHAIMRLDMAGRDLTDYLMKILSERGYSFTNSAEREIVRDIKEKLCYVALDFEQELQTASQSSSLEKSYELPDGRVITIGNERFRAPEALFHPSMLGLEAAGIHETTFNSIMKCDVDVRKDLYGNIVMSGGTTMYPGIAERMHKEISALAPTSIKVKITAPLERKYSVWIGGSILASLGTFQQMWISKQEYDEAGPTIVHRKCY",
    "output": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTIAFQLAVFASIAIPFILVIGVPVVLASPDGWSSSRNVVFSGASSWIGLVFLVGILNSLIS",
    "output": "Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSMKGKETMSEQNERIVMGKLGSTYGIRGWLKVFSYTDNAESIFDYSPWYLKLKGEWVEYKVESWKRHGQGYVCKLAGLDVREDAQLMTNFEIAIDPASLPELSEDEFYWRELFGMQVFTTKGYNLGEVTDLLETGSNDVLVIKANLKDAFGQKERLIPYLEEQVIKKVDREARRIEVDWDPGF",
    "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "LQDIINEFGGAMPQTFGVPVEEIVRGIKMGVRKVNIDTDCRMRMTGQFRRIAEQNKAEFDPRKFLKPAMDAMRDLCKARLEAFGTAGHASKIKVIPMDDMAKRYASGSLAPKTN",
    "output": "Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MYRTHTCGELNIKDVGKKVVLSGWVDRIRDLGGIKFIILRDRYGVTQVVVNPESPAYEISQKIGREWVIQIEGTVSERPESTKTETQTGEIEVIVEKINVLSKAELPPFYPGDKVSEDLRLKYRYLDLRDKNMNKNLIIRHKMAQAAREFLNKHGFLEIETPYLTKSTPEGARDFLVPSRLQKGKFYALPQSPQLFKQLLMVSGFDKYYQFARCFRDEDLRADRQPEFTQIDIEMSFVEMEDVINLMENFVRYVYSSVGIKLPEKFDRITYDEAMEIYGSDKPDRRFGMELKDLTNYFKDTDFKIIKNVINNGGSIKGFITQIPISRKIASELESYVKEFGLGGLLWFKLENGEISSPTNKFLGGSYENISKDYNLKDGDVVLLAAHTNREQLNTALGALRLRIAKEHFKNLEEGFDALWVVDFPFLEWNEEEKRYVARHHPFTMPKNIDSKPEDIKAYAYDMILNGNEIGGGSIRIHNSEIQRKVFEIIGLTNKEAEEKFGFLLEALKYGAPPHGGIAFGFDRMVSIALRTSSIRDVIAFPKTTSGTCQLTGAPSSVDKSQLEELSIKLFDIKEGGDENE",
    "output": "Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MMEETTKIPQATAKRLPLYHRYLKYLDESGKERVSSAELSEAVKVDSATIRRDFSYFGALGKKGYGYNVSYILDFFSKTLSQDKQTNVALIGVGNLGTALLHYNFMKNNNIKIVAAFDVDPAKVGSVQQDIPIYHLNDMEEIVRENGVEVVILTVPADEAQVTVDRLIEADVKGILNFTPARISVPKQVRVHHIDLTTELQTLIYFLENYPAKTE",
    "output": "Modulates transcription in response to changes in cellular NADH/NAD(+) redox state."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRLVVCLVFLASFALVCQGQVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGCPISCRGISFSQARSYCSRLGRCCHVGKGYSG",
    "output": "Antibacterial and antifungal activity. Presents chitin-binding activity (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKLALIEREKKRAKLAAKFAPKRAALKAIIDDQEKSEEERYMARLELQQLPRNANPTRQRNRCAITGRPRGTFRKFGLARNKIREIAFKGEIPGLTKASW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPKSKRDKKVSLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFSVANMRNSKLKDIRNAWKHSRMFFGKNKVMMVALGRSPSDEYKDNLHQVSKRLRGEVGLLFTNRTKEEVNEWFTKYTEMDYARAGNKAAFTVSLDPGPLEQFPHSMEPQLRQLGLPTALKRGVVTLLSDYEVCKEGDVLTPEQARVLKLFGYEMAEFKVTIKYMWDSQSGRFQQMGDDLPESASESTEESDSEDDD",
    "output": "Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKEVSLRGISKTFGQLTVLDRIDLEIHSGEFLVLVGPSGCGKSTLLRMVAGLEPISGGDLVIGGERANELPPQKRNIAMVFQSYALFPHMTARENIGFGPRIRGEKAAETAAKVDHAASILNLHSYLDRYPRQLSGGQRQRVAMGRAIVREPSVFLFDEPLSNLDAQLRVQMRTEIKALHQRLKSTVIYVTHDQIEAMTMADRIVVMNQGKIQQIGAPLDLYDRPANKFVAGFIGSPSMSFIPGTVADGFFCTGEGEKIAVSAAAKGARAAEAGIRPENFVIAREGAGLTLVVEVIEPTGPETHIYGRIAGEPVRAVFRERIQLAPGEQVPVTAGSEHIHLFDKESGLPL",
    "output": "Probably part of an ABC transporter complex. Probably responsible for energy coupling to the transport system (Probable)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MANTLVGRKRIRKFFGKIREVAEMPNLIEVQKASYDQFLMVDEPEGGRPDEGLQSVFKSVFPISDFSSTALLEFVKYTFEAPKYDVDECRQRGITFAAPLKVTLRLIVFDVDPDTGAKSVKDIKEQDVYMGDMPLMTENGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAARIIPYRGSWLDVEFDAKDIVYARIDRKRKIPVTSLLFALGLDGEEILSTFYNRITYARDGRDWRVPYDAERLKGFKATTDLIDADSGEVVLEAGKKLTARAARQIAEKGTKALRATDEDLVGQYIAEDMVNYKTGEIYAEAGDEISEKLLKGLSDVGIEEIPVLDIDHVNVGPYIRNTLAVDKNSAREGALFDIYRVMRPGEPPTLDTAEAMFHSLFFDAERYDLSAVGRVKMNMRLDLDAPDTMRTLRREDMLAVVKALVDLRDGKGEIDDIDHLGNRRVRSVGELMENQYRLGLLRMERAIKERMSSVDIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIETPFRRVRGGVVTDEVVYLSAMEEAKYYVAQASAAMDAERRLTEDLVVCRRAGEVIVVAPDRVDLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRADAPFVGTGMEAVVARDSGAAIAARRAGVIDQVDATRIVIRATEETDPTKPGVDIYRLQKFQRSNQSTCITQKPLVRVGEVVKKGDIIADGPSTEFGELALGRNVLVAFMPWNGYNFEDSILLSERIVKDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVHAGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVPPGVTGTIVEVRVFNRHGVDKDERAQAIEREEIERLAKDRDDEQAILDRNTYARLADVLVGQSPVAGPKGFKKDTLLTREVLADYPRSQWWQFAVVDDRMMTEIEAMQKQYDESKKRLEQRFLDKVEKLQRGDELPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLGWAAAGLGRQVAQAVDAYLRNQDAQPLREQMSRIYSPSELEGLSDRELAEVGNNLRRGVPMATPVFNGAKEADIEAMLEMAGLDRSGQSTLYDGRTGEPFDRKVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELISSKRAANDQLEAPPEAAE",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTNIAILGTASDVGKSIVATALCRIFSNAGVDVAPYKAQNMSNNSGVTPDGFEMGRAQIVQAQAARVAPHADMNPVLLKPNTDTGAQVVLQGKVCADKSAREYFGDTQRWAEAAFESLDRLMVRHELLVIEGAGSCAEMNLYQRDFVNFKTARRAGAAVILVADIDRGGVFAQVVGTLAVIPPEDRALVKGVIINRFRGDKSLFEGGVKMLESMTGVPVLGVIPYFRGFTIDAEDAVPLSSVVDPKQEPSGDKIGVAAIYFPHISNFTDLAPLERDPSVELHYLHRPKSLDGYKALILPGSKNVRGDLAWLETMGWRDEIEKFRKRGGIIVGLCGGYQMLGASIADPYGVEGAPGASAGLAMLPVETVLEREKALCNSVGKIAGTPFFVSGYEIHMGRTALEPGASPLLEVTERNGVATDDFDGAKSADGQVTGTYFHGFFDRPEVRTWFLRLLDGGYESPRGASVADPFELLAKHFSENLDLEKLFAIAGLSVKGEKES",
    "output": "Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEIKGINHLLFSVSHLDTSIDFYQKVFGAKLLVKGRTTAYFDMNGIWLALNEEPDIPRNDIKLSYTHIAFTIEDHEFEEMSAKLKRLHVNILPGRERDERDRKSIYFTDPDGHKFEFHTGTLQDRLRYYKQEKTHMHFYDETAF",
    "output": "Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSPPISPTPPPLQPPFPPTAIARGPDRPDPPPQHQQAAESLVNAAAQHVAPTCPPTSDELPQMEDQATNSSNDSLIPSRQAPDQEETENAITAGTPPDEMEPTKDAQTVRFSSSSPASYSTHEYPTEGINEPRTSSRAPNTASSQMAESSCDFRSSRDIGSIRMGASALVSALNALPWEEDDDSDDGEDDDEFIEPARGSSSTIYERKQRPQTPSTSHGFHPTHTLHFPFRQNAIARRACQPGTTELDYQYATPETSSRRTSAAGSESSSEGEVPLPKGFVSHPNLIVPSGEGEAAAHPDPKLISDRITKEQQIADVEEQAEILRSAEEQEMRLGKEFVPPKSRDSADLNVDAALREGGSEREDVIEEQMQTNEAEKRLTRNEKLAERLMEVFGLEEREEVLEEMKCWLLRSVMLKGYMYLTKRHICFFANMPNENNLLVKSGPLHKKASRSKLNTKFWVVLKNDVLSWYESTSDPYFPKGNISLQYCHSCDAVSGTRFKVRTSERNYTFTADTESSRDEWVKAIQKVMFKTQHEGETIKLIIPLEAIVDVEKSPTLEFTETIEVKCIDAEDQMSVDSYFFASFPDNDYAFSAIQKLVRERPSPPELPRISSVTTIHANQEPLDTSHATIKRHGTDSSAEKLGMASHRPFRKISSVLKPLILKSSDGEPLEEHSQGPHHNDEDASHLPHIEAISNRRRSEEESDNDYFDGYPPRQVGPPPPSMNDDARNWRPSWIRKPASKLFGSSPSGSFVSHPGRLPTDSSTTVTESGPSLRSRTGRTKQASVTEVMEPPIQYEEEVSEDEMSNKPSVVDSNSAETARKRAARLSWTSETSSGSQMVKSKSDFSMLGSESGHSESAETVRKFRTFFALSDKEELIDHFPGYLYRVLPVSGRFFISTNYFCFRSSQLLYKTKESFRLMIIPIRDLYGLKAQKAFRFGHSGLTVVIKGHEEIFIEFRSASRRKACIALLEERMEAVRLSGENTIVDSHKIEARIMEDLDESTPVEPKSPWPVSPSPLFGSTTSTSFLEFKPEPMKITCLTIGSRGDVQPYIALCKGLQAEGHITKIATHGEYKAWVEGHGIAFESVGGDPAELMQMCVDNGMFTVSFLKEGLQKFRGWLDDLLNSSWEACQGSDLLIESPSAMSGIHVAEALRIPYYRAFTMPWTRTRAYPHAFAVPEHGRGGPYNYMTYTMFDQVFWRAISGQVNRWRRNVLGLDATTFDKMEQHKVPFLYNFSPTVVPPPLDWTEWIHVTGYWFLDKADEKQGEKSWTPPQGLVDFIDKAHGEEKKVVYIGFGSIVVSDPEEMTRCVVEAVVNSGVCAILSKGWSDRGSKKGEPKGDSEGADGVKYPPEIFAIDSIDHGWLFPRIDAACHHGGAGTTGASLRAGIPTIIKPFFGDQAFWAERVESLNVGSSIRRLTSHQLASALIKATTDEKQISKARVVGEMIRKENGITRAIEAIYRDLEYAKSIIKSLPSTDDRTPERISSHLHPLTTADLSFNRVRSRSRSRSRSSQGRFSPRRHTVDDDGWSVVSGGSRSRSGSASAVTSPERRPLNIGSALGSHVFKTALLPNTFGKWRNLEEGDDR",
    "output": "Probable sterol 3-beta-glucosyltransferase that is not involved in cytoplasm to vacuole transport (Cvt), pexophagy or nonselective autophagy (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRSHYCGDVNKSHVGQEVTLVGWVNRSRDLGGVVFLDLRDREGLVQVVYDPDLPEVFNVASTLRAEFCVQVKGVVRARPDSQVNAQMKTGEIEVLGKELTIINSSEPLPLSLDNYQNNSEEQRLKYRYLDLRRPEMAQRLMFRAKVTSAVRRFLDSNGFLDIETPILTKATPEGARDYLVPSRTYKGQFFALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMTSEQVMAKTEEMMRGLFLEMLNVDLGEFPRMTYNEAMRRFGSDKPDLRNPLELVDVADLLKEVEFAVFSGPANDEEGRVAALRIPGGASLSRKQIDDYTKFVGIYGAKGLAWMKLNDLTQGLEGIQSPVLKFLNEGIVNEIISRTGAQTGDIILFGADNATVVAESMGALRLKAGEDFNLLEGQWRPLWVVDFPMFEKINGSFHAVHHPFTAPRGVTPQELEANPANRVSDAYDMVLNGCELGGGSVRIHNQEMQSAVFRILGITDEEAKEKFGFLLEALRYGTPPHAGLAFGLDRIIMLMTGASSIRDVMAFPKTTTAACPLTNAPGFANPQQLAELGISVVKAAKTED",
    "output": "Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDALLIQGGNPLAGEVRISGAKNAALPILTASLLTAEPLRLGNVPHLKDISTMLALLGHMGVRVTLDDKNHVTLSGDSIPHKEAPYEMVKTMRAAILVLGPTLARFGEARVSLPGGCAIGSRPVDLHIKGLQAMGADISIEHGYIHARCKRLQGARIVMDMVTVTGTENLMMAAALAEGTTVLENAAREPEVVDLARCLIAMGAKIEGAGTDVITVHGVEALHGAEYSVMADRIETGTFLVAAAMTGGRVRATHTSPDTLEAVISKLREAGAKVSVGDDWIEVESTGKLDSVDVRTAPHPAFPTDMQAQFMAMNTIAVGAASVTETIFENRFMHVQELRRLGANIEVSGHTALVRGVARLDGATVMATDLRASACLVLAGLVAAGETTIERIYHLDRGYERIEEKLTQLGGRIKRVH",
    "output": "Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQIASSPFTHNQRSTRRIMLLVILACIPGIIAQTYFFGYGSLIQVMLAMITALLAEGAVLQLRKQPVMARLQDNSALLTALLLGISLPPLAPWWMIVLGTLFAIVIAKQLYGGLGQNPFNPAMVGYVVLLISFPVQMTSWLPPLPLQGTSVGFYDSLLTIFTGYTHSGENIHQLQVGYDGISQATPLDTFKTSLRSQPADQILQQPIFGGVLAGLGWQWVNIGFLVGGLLLLWRKAIHWHIPVSFLLALGGCAAVSWMIAPQSFASPMLHLFSGATMLGAFFIATDPVSASTTPRGRLIFGALIGILVWLIRVYGGYPDGVAFAVLLANITVPLIDHYTQPRVYGHKSGHK",
    "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKSKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNSYDARDSETNVMVHVYGPHIFHTDNETVWNYVNKHAEMMPYVNRVKATVNGQVFSLPINLHTINQFFSKTCSPDEARALIAEKGDSTIADPQTFEEQALRFIGKELYEAFFKGYTIKQWGMQPSELPASILKRLPVRFNYDDNYFNHKFQGMPKCGYTQMIKSILNHENIKVDLQREFIVEERTHYDHVFYSGPLDAFYGYQYGRLGYRTLDFKKFTYQGDYQGCAVMNYCSVDVPYTRITEHKYFSPWEQHDGSVCYKEYSRACEENDIPYYPIRQMGEMALLEKYLSLAENETNITFVGRLGTYRYLDMDVTIAEALKTAEVYLNSLTENQPMPVFTVSVR",
    "output": "Involved in the biosynthesis of the galactose-containing O-side-chain polysaccharide backbone structure of D-galactan I which is a key component of lipopolysaccharide (LPS). Catalyzes the interconversion through a 2-keto intermediate of uridine diphosphogalactopyranose (UDP-GalP) into uridine diphosphogalactofuranose (UDP-GalF) which is the biosynthetic precursor of galactofuranosyl residues."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAEKKGSSSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEATASEKDAAAATRSDLPTPHEIRESLDQYVIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQVDTTNILFICGGAFDGLEKVIMQRSDKTGIGFAAQVQSKEEREVSEVLPQTEPEDLIKFGLIPELIGRLPVVATLAKLDETALVQILIEPKNALVKQYQKLLAMEGVELEIRPAALSAIARKAIRRKTGARGLRSILEQSLMDVMYDLPNYKGVQKVVIDESTINGDAPPLLMYEEQQPKVSGSN",
    "output": "ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARFMGPRFKLARHLGVNVFGHPKALNRGVKQHKLSEYGEQLLEKQKLRAYYGVLEKQFKKIVFNALKSKEKSEDILVQSLERRLDNLVYRLGFGSTLREARQMVSHGHILVNGQKVDIPSYKVNIGDEVSLRSKSRKIQTYASNFTTIIPAVTYIEKDTESFSGRLIRLPKSVEVPVMVKYSKVLEFYSKN",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAERKPNGGSGGASTSSSGTNLLFSSSATEFSFNVPFIPVTQASASPASLLLPGEDSTDVGEEDSFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQPHWFYCKEVEYKQLWMPFSVFDSLNLEEIYNSVQPDPESVVLGTDGGRYDVYLYDRIRKAAYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFVVHGIGPVCDLRFRSIIECVDDFRVVSLKLLRTHFKKSLDDGKVSRVEFLPVHWHSSLGGDATGVDRNIKKITLPSIGRFRHFTNETLLDILFYNSPTYCQTIVEKVGMEINHLHALFMSRNPDFKGGVSVAGHSLGSLILFDILSNQKDLNLSKCPGPLAVANGVVKQLHFQEKQMPEEPKLTLDESYDLVVENKEVLTLQETLEALSLSEYFSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVEHKAAKLKKAASEKKAVAATSTKGQEQSAQKTKDMASLPSESNEPKRKLPVGACVSSVCVNYESFEVGAGQVSVAYNSLDFEPEIFFALGSPIAMFLTIRGVDRIDENYSLPTCKGFFNIYHPLDPVAYRLEPMIVPDLDLKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEEEKQVVEAEKVVESPDFSKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPQH",
    "output": "Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTDDGYTVGDYLLDRLAELGVTEVFGVPGDYQLEFLDHVVAHPRITWVGGANELNAGYAADGYGRLRGMAALVTTFGVGELSAANAIAGSYAEHVPVVHIVGAPSKDSQAARRIVHHTLGDGDFEHFLRMSREITCAQANLVPATATREIDRVLSEVHEQKRPGYLLIATDVARFPTEPPTAPLPRHSGGTSPRALSLFTEAATQLIGEHRLTVLADFLVHRMGCVEALNKLLTADTVPHATLMWGKSLVDESSPNFLGIYAGAASEGSVREVIEDAPVLVTAGVLFTDMVSGFFSQRIDPARTIDIGVNQSVVAGQVFAPLDMAAALDALASILAERGIESPALPPAPAPQRPAAPPRDAVLTQEALWDRLAEALTPGNVVLADQGTSFYGLAGHRLASGVTFIGQPLWASIGYTLPAALGAGLADRDRRTVLLIGDGAAQLTVQELGAFGREGLTPVVVVVNNNGYTVERAIHGVTARYNDITAWRWTELPAALGVPDALTFRCATYGELDDALTVAAETQDRMVFVEVMLERMDIPPLLGELAQSASAANAK",
    "output": "Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICAWCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH",
    "output": "Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSATTAAVPFWRAAGMTYIGYSNICAALVRNCLKEPFKSEAASREKVHFSISKWTDGKQEKPTVRTESDD",
    "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKFLVSSDDTGVVKEVICNRGTDTSKQDATQPISVKNFCTEPNCSRKNRIIHMINYQEKYLVAIRIGGELSVYEIADDEYEIEDEYKYNLLHNYKLEVSSSDKPISLFTVDILEAVAVAFSSGKVFFVNFNDDKFDKEPVLVQLPGGKEIAEFSKNPSVEGIFGYGGEENDVRIVKLYESDITSEIFDTENVENNFKSEVVFTAKNVKNDHLDLRVPVWITKIRFFTEQPEKGYKFITATHYGQIRVYDTNHGRRPVRDFTVCQKPILTLTFANEEESEVIISDSHNLIAKHSLIQVDDKASKTHSASAGDIIKPVAKLLGRFVDQFGATYGVEVGEGLLVTGGLDRYLRVFDLASREIVAKVYVGVEVSSVVVLDYEEEESQEEIVGDVELLKKSEKRKRTLPVVEREESDEEDLWNQLEEKDIKRKKS",
    "output": "Involved in the biogenesis of the 60S ribosomal subunit."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "METPFYGEEALSGLAAGASSVAGAAGAPGGGGFAPPGRAFPGAPPTSSMLKKDALTLSLAEQGAAGLKPGSATAPSALRPDGAPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSTQFLYPKVAASEEQEFAEGFVKALEDLHKQSQLGAATAATSGAPAPPAPADLAATPGATETPVYANLSSFAGGAGPPGGAATVAFAAEPVPFPPPPGALGPPPPPHPPRLAALKDEPQTVPDVPSFGDSPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY",
    "output": "Transcription factor binding AP-1 sites (By similarity). Heterodimerizes with proteins of the FOS family to form an AP-1 transcription factor complex, thereby enhancing their DNA binding activity to an AP-1 consensus sequence 3'-TGA[GC]TCA-5' and enhancing their transcriptional activity (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAPQPLALQLEQLLNPRPREADPEADPEEATRARVIDRFDEGEEEKDDLAVSSIRKLAPVSLLDTDKRYSGKTTSRKAWKEDHWEQALPSSSDNEASDEGGSEDGDSEGLGLEEISEDVDEDLEDNKISDEGGSEDGDSEGLGLEEFSEDVEEDLEGEDEEDREEDRNSEDDGVVAAFSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRHIVNGAKPNTESEEISSEDDELVGEKKKQRKAPPKRKLEMEDYPSFMAKRFADFTIYRNHTLQKWHDKTKLASGKLGKGFGAFERSILTQIDHIMMDKERLLRRTQTKRSAYRVLGKPEPVPEPVAETLPGEPETLPQGPANAHLRDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIRKKVDRKASKGRKLRFHVLSKLLSFMAPIDHTAMSDDARTELFRSLFGQLNPPDADRGK",
    "output": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKGVFERTKPHINVGTIGHVDHGKTTLTAAITKVLAKHVPDDPANKEVAFEQIDNAPEERQRGITIATSHQEYATKNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYIVVYLNKADMVDDPELLELVEMEVRELLSEYEFPGDEVPVVVGSALKALEGDEGELGEQSILKLLEALDEYIPEPKRDIDKPFLLAVEDVFSIQGRGTVATGRVEQGKLRLNEEVEIVGIRPTRKTVVTGIEMFNKSMQEAQAGDNIGVLLRGIKRDEIERGQVLAAPGSITPHTRFKAEVYVLSKEEGGRHTPFFSHYRPQFYFRTTDVTGEIFLEEGVEMVMPGDNTVMEVQLISPIAMDEGLNFAIREGGRTVGAGVVTQIIE",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNEFINIFSSSDPENVSSTVKLLLLLTVFSVAPGILILMTCFTRIVIVLSFVRTSLATQSMPPNQVLIGLALFLTFFIMAPTFSEINKEALTPLMDNKISLDEAYTKAEEPIKEFMSKHTRQKDLALFMNYAKMDKPESLKDIPLTTMVPAFAISELKTAFQIGFMIFIPFLIIDMVVASVLMSMGMMMLPPVMISLPFKILLFVLVDGWYLIVKSLLQSF",
    "output": "Plays a role in the flagellum-specific transport system."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MCGPAMFPAGPPWPRVRVVQVLWALLAVLLASWRLWAIKDFQECTWQVVLNEFKRVGESGVSDSFFEQEPVDTVSSLFHMLVDSPIDPSEKYLGFPYYLKINYSCEEKPSEDLVRMGHLTGLKPLVLVTFQSPVNFYRWKIEQLQIQMEAAPFRSKEPCMAEEVCSMSWYTPMPIKKGSVVMRVDISSNGLGTFIPDKRFQMNINGFLKRDRDNNIQFTVGEELFNLMPQYFVGVSSRPLWHTVDQSPVLILGGIPNEKYVLMTDTSFKDFSLVELSIDSCWVGSFYCPHSGFTATIYDTIATESTLFIRQNQLVYYFTGTYTTLYERNRGSGSWIRVLASECIKKLCPVYFHSNGSEYIMALTTGKHEGYVHFGTIRDGQVSFEMLPRQWSVCEQIGVTTCSIIWSEYIAGEYTLLLLVESGYGNASKRFQVVSYNTASDDLELLYHIPEFIPEARGLEFLMILGTESYTSTAMAPKGIFCNPYNNLIFIWGNFLLQSSNKENFIYLADFPKELSIKYMARSFRGAVAIVTETEEIWYLLEGSYRVYQLFPSKGWQVHISLKLMQQSSLYASNETMLTLFYEDSKLYQLVYLMNNQKGQLVKRLVPVEQLLMYQQHTSHYDLERKGGYLMLSFIDFCPFSVMRLRSLPSPQRYTRQERYRARPPRVLERSGFHNENSLAIYQGLVYYLLWLHSVYDKPYADPVHDPTWRWWANNKQDQDYYFFLASNWRSAGGVSIEMDSYEKIYNLESAYELPERIFLDKGTEYSFAIFLSAQGHSFRTQSELGTAFQLHSQVDVGVVLADPGCIEASVKQEVLINRNSVLFSITLKDKKLCYDQGISGHHLMETSMTVNVVGSSGLCFQETHLGPHMQGNLMVPVFIGCPPGKRLAFDITYTLEYSRLKNKHYFDCVNVNPEMPCFLFRDIFYPFFLIQDLVTGDSGSFQGSYVLLVVGGGPTLDSLKDYSEDEIYRFNSPLDKTNSLIWTTRTTRTTKDSAFHIMSHESPGIEWLCLENAPCYDNVPQGIFAPEFFFKVLVSNRGVDTSTYCNYQLTFLLHIHGLPLSPKRALFIIMVSASVFVGLVIFYIAFCLLWPLVVKGCTMIRWKINNLIASESYYTYASISGISSMPSLRHSRMGSMFSSRMTEDRAEPKEAVERQLMT",
    "output": "Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAEKRNIFLVGPMGAGKSTIGRQLAQQLGMEFFDSDSVIEERAGAEISWIFDIEGENGFRKREERIINELTQKQGIVLSTGGGVVLSKENRNHLSARGIVVYLQTTVAKQFERTQRDKKRPLLQGVEDARQVLENLAVIRNPLYEEVADITLPTDEQSAKVMANQIIDLIDNFHG",
    "output": "Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSNVLELTIPASTANLGVGFDSIGMALDKFLHLSVKETSGTKWEYIFHDDASKQLPTDETNFIYHVAQQVASKYSVDLPNLCIEMRSDIPLARGLGSSASALVGAIYIANYFGDIQLSKHEVLQLATEIEGHPDNVAPTIYGGLIAGYYNDVSKETSVAHIDIPDVDVIVTIPTYELKTEASRRALPQKLTHSEAVKSSAISNTMICALAQHNYELAGKLMQQDGFHEPYRQHLIAEFDEVKTIAIQHNAYATVISGAGPTILIFSRKENSGELVRSLNSQVVSCHSELVDINISGVKERIVYQ",
    "output": "Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MEMEHINENTIRVLIGNEDLADRGITFLDLLGNHKDVENFFYSILEEVDVEDEFQGSEAVTFQVLPKNDGLELFISKNVAMDDLSSLEGLSEVNADVSELIRKQIEADKAAADELDEMEATDETNRNVIFELDNFEAMIQLSKEVFMQSVLTNLYTYNDRYYLQVLFLTDELEKTNVDNEIAQILEFAHKTTVTQDTLVEYGTCIMERSALELTRYYFND",
    "output": "Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNNWVTTYENHNYGLVISSRIRLARNLAKIPFSHKLNIEESKKVIKNVENAFYTFSNTEEKFKSNYLWDKNDNEKNIYLEKHLISKNLIDNSSKAAFILDDKETISIMINEEDHVRIQCITGGLNLEEVYDVSEKIDDLLEENLEYAFDEKLGYLTACPTNVGTGLRASVMLHLPSLSLNNQINGFLNALAQVGMTIRGLYGEGSKAIGNIYQISNQVTLGRSEEEILSNLKALVLQIINQEIISRENLMKKYKYELEDKIYRALGVLKSAVLLNSSECLKLLSDVRLGVEMGIIKDVNGITLNKLLVESQPATIQKIYGESLSNKDRDFNRAKFVREKLAVNTA",
    "output": "Catalyzes the specific phosphorylation of arginine residues in proteins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTRLAEILDQMSAVLNDLKTVMDQEQQHLSMGQINGSQLQWITEQKSSLLATLDYLEQLRRKEPNTANSVDISQRWQEITVKTQQLRQMNQHNGWLLEGQIERNQQALEMLKPHQEPTLYGANGQTSTTHRGGKKISI",
    "output": "Required for the efficient initiation of filament assembly."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVFEGHLVGTELKVGVVVGRFNEFITSKLLGGALDGLKRHGVEEADIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTVIRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKQWA",
    "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNRRLLVRSISCFQPLSRITFGRPNTPFLRKYADTSTAANTNSTILRKQLLSLKPISASDSLFISCTVFNSKGNIISMSEKFPKWSFLTEHSLFPRDLRKIDNSSIDIIPTIMCKPNCIVINLLHIKALIERDKVYVFDTTNPSAAAKLSVLMYDLESKLSSTKNNSQFYEHRALESIFINVMSALETDFKLHSQICIQILNDLENEVNRLKLRHLLIKSKDLTLFYQKTLLIRDLLDELLENDDDLANMYLTVKKSPKDNFSDLEMLIETYYTQCDEYVQQSESLIQDIKSTEEIVNIILDANRNSLMLLELKVTIYTLGFTVASVLPAFYGMNLKNFIEESEWGFTSVAVFSIVSALYITKKNFNSLRSVTKMTMYPNSPANSSVYPKTSASIALTNKLKRRRKWWKSTKQRLGVLLYGSSYTNKANLSNNKINKGFSKVKKFNMENDIKNKQNRDMIWKWLIEDKKN",
    "output": "High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix . Essential for the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing. It also suppresses a variety of mitochondrial intron mutations and its absence may disturb the assembly of mitochondrial membrane complexes ."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFGKLLTKVFGSRNDRTLKGLQKVVNKINALEADYEKLTDEQLKAKTAEFRERLAAGASLDSIMAEAFATVREASKRVFEMRHFDVQLLGGMVLDSNRIAEMRTGEGKTLTATLPAYLNALTGKGVHVITVNDYLARRDAENNRPLFEFLGLTVGINVAGLSQQAKKDAYNADITYGTNNEFGFDYLRDNMAFSPQERVQRPLHYALIDEVDSILIDEARTPLIISGAAEDSSELYIKINTLIPNLIRQDKEDSEEYVGEGDYSIDEKAKQVHFTERGQEKVENLLIERGMLAEGDSLYSAANISLLHHVNAALRAHTLFERDVDYIVQDGEVIIVDEHTGRTMPGRRWSEGLHQAVEAKEGVRIQNENQTLASITFQNYFRQYEKLAGMTGTADTEAFEFQHIYGLDTVVVPTNRPMVRKDMADLVYLTANEKYQAIIKDIKDCRERGQPVLVGTVSIEQSELLARLMVKEKIPHQVLNAKFHEKEAEIVAQAGRTGAVTIATNMAGRGTDIVLGGNWNMEIEALENPTAEQKAKIKADWQERHDAVVAAGGLHILGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDSLMRIFASDRVSGMMKKLGMEEGEAIEHPWVSRAIENAQRKVEARNFDIRKQLLEFDDVANDQRQVVYAQRNELMDAESIEDTIKNIQDDVISAVIDQYIPPQSVEELWDVPGLEQRLQQEFMLKLPIQEWLDKEDDLHEETLRERIITSWSDAYKAKEEMVGAPVLRQFEKAVMLQTLDGLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFQQLLSTLKHDVISVLSKVQVQAQSDVEEMEARRREEDAKIQRDYQHAAAEALVGGDDGSDEMMAHTPMIRDGDKVGRNDPCPCGSGRKYKQCHGKLS",
    "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAARHHAFILAGTGSGCGKTTVTLGLLRLLQKRALRVQPFKVGPDYLDTGWHTAICGVASRNLDSFMLPPPVLNALFCEQMRQADIAVIEGVMGLYDGYGVDPNYCSTAAMAKQLGCPVILLVDGKAVSTSLAATVMGFQHFDPTLNLAGVIVNRVTSDAHYQLLKNAIEHYCSLPVLGYVPPCDGVALPERHLGLITARESLVNQQSWHDFAATLEQTVDVDALLSLSVLSALPAGMWPERPDNTAGAGLTLALADDEAFNFYYPDNIDLLERAGVNIVRFSPLHDRALPDCQMIWLGGGYPELYAADLAANTVMLKHLRAAHQRGVAIYAECGGLMYLGSTLEDSGGEIHQMANIIPGHSKMGKRLTRFGYCEAQAMQPTLLAAPGEIVRGHEFHYSDFIPETPAVMACRKVRDGRVLQEWTGGWQTGNTFASYLHVHFAQRPEMLQHWLAAARRVL",
    "output": "Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Is able to use other nucleotide triphosphates as substrate, such as GTP or UTP, although less efficiently than ATP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAELTISANDIQSAIEEYVGSFTSDTSREEVGTVVDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDEHSVGAVILGNSENIEEGQQVKRTGEVLSVPVGDAFLGRVINPLGQPIDGRGDIKAETRRALELQAPSVVQRQSVKEPLQTGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWETGDPKKQVRCVYVAVGQKGTTIASVRRALEEGGAMDYTTIVAAPASDSAGFKWLAPYTGSAVAQHWMYDGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDELGGGSLTGLPIIETKANDISAYIPTNVISITDGQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAIKEVAGSLRLDLSQYRELEAFAAFASDLDATSKAQLDRGARLVELLKQPQYQPMPVEEQVISIFLGTGGHLDSVPVEDVRRFETELLDHIRASEENLLSTIRDTQKLTEETEEALTKVINHFKKGFASSTGESVVPDEHVEAMDEEDLGKESVKVKKPAPQKKK",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYIGDVNPPGRSSLDSIEMAYARQIYIYNEKIVSGHLQPNLVDLCASVAELDDKSISDMWAMVKQMTDVVLTPATDALKSRSSVEVRMDFVKQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPSPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVSRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDITDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSATRPQRVIEDRDSQLRSQARALITFAGMIPYRTSGDTNARLVQMEVLMN",
    "output": "Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC (By similarity). During renal development, regulates podocyte migration and proliferation through SMAD4 signaling (By similarity) ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIKKSAAILAGGKSSRMNYINKAFLKYEENYFIERIIKALEDYEEIIIISNNPEEYTEFGLKVFKDIYPSQGPLSGIHSALNYIKNDYCLVVACDMPFINKEVVNYLGNIKEDYEILIPKFQERLQPLCAIYKKSCKDIMEKELINNSNKLIKTCFKFSMKVVEEFPFIEKIHKKEIKNFYNINTVHEYEDLIRKKEI",
    "output": "Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEKMYNVGKIVNTHGLIGEIRVIATTDFPEERFQVGNTVYLFEKNSKKPEKLIIRSHRKHKNFDLLMFEGFTGIHQVERMKEGVLKIKEAQLTDLEENEFYFHEIIGCIVVTTDGKELGEITEILTPGANDVWVVKGSDKKEKLIPYIADVVKEININDKKITIEVMEGLLD",
    "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKNLTGIFSALLVAFNEDGSINEQGLRQIIRHNIDKMKVDGLYVGGSTGENFMLSTAEKKEIFRIAKDEAKDQIALIAQVGSVNLQEAVELGKYATELGYDCLSAVTPFYYKFSFAEIKHYYDTIIAETGNNMIVYSIPFLTGVNIGVEQFGELYKNPKILGVKFTAGDFYLLERLKKAYPNHLIWAGFDEMMLPAVALGVDGAIGSTFNVNAPRARQIFELTKQGKLAEALAVQHVTNDLIEGILANGLYLTIKELLKLQGVEAGYCREPMTAKATDKQLEVAKALYAKFL",
    "output": "Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MNKLALYCRSGFEKELAAEITEKATALGVFGFARVVENSGYVIFECYQIGEADLLARKITFSQLIFARQLIVVSDLISNLSVQDRISPIIEYYRQQEKILNLKQSSDIWVETADTNEAKTLAAFCRKFTVPLRQALRKQGWLQAKNKKSGITLHIFFTQSNSCYIGYSYNNNHAEHIMGIPRLKFPAEAPSRSTLKLEEAILYFIPPNQEATRFNENKYAVDLGACPGGWTYQLVRRGVFVYAVDHGKMATSLHETGRIEHCAEDGFKFRPPKHCKIDWLVCDMVEQPRRIADLISQWLVKGWCKETIFNLKLPMKKRYFEVQQCLRQIEDKLNKQNISFQLQAKHLYHDREEITVYIRLM",
    "output": "Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSKETFQRNKPHINIGTIGHVDHGKTTLTAAITRTLSGDGLADFRDYSSIDNTPEEKARGITINASHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSATDGAMPQTKEHILLARQVGVPYIVVFLNKIDMISEEDAELVDLVEMELAELLEEKGYKGCPIIRGSALKALEGDAAYIEKVRELMQAVDDNIPTPEREIDKPFLMPIEDVFSISGRGTVVTGRIERGIVKVSDKVQLVGLRDTKETIVTGVEMFRKELPEGRAGENVGLLLRGIGKNDVERGMVVCLPNSVKPHTRFKCAVYVLQKEEGGRHKPFFTGYRPQFFFRTTDVTGVVTLPEGVEMVMPGDNVEFEVQLISPVALEEGMRFAIREGGRTIGAGTISKIIA",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATKPQDANTTSREAITSKADSPPRPTALIFDSGVGGLSVYQEIRQLLPNLHYIYAFDNVAFPYGEKSGEFIVERVLEIVTAVQQSHPLAIVVIACNTASTVSLPALRERFAFPVVGVVPAIKPAVRLTRNGVVGLLATRATVHASYTLDLIARFATDCKIELLGSSELVEAAETKLHGGVVPLEVLKKILHPWLSMREPPDTIVLGCTHFPLLTEELAQVLPEGTRMVDSGAAIARRTAWLISSQENVISSQDENIAYCMALDEDTDALLPVLQSYGFPKLQKLPI",
    "output": "Provides the (R)-glutamate required for cell wall biosynthesis."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSEDPQPESSALSDLKIASHAPLDDAQRAGRMKCTRCGCSRMFFCYSCGALVGLQPGDVPRVTLPVKIDIIKHPNETDGKSTAVQAKLLAPQDVTIYTYPCIPELDQSAENIVLVFPGPDAMSVEELWEYFCADGRPRVKRVKAEAESLRCPIQRVVFIDSTWNQTSRIITDERLQALPNVELKSRKTCFWRRQKGSPDTYLATIEAIYYFLKDLHCHYFCEYTGEYDNLLFFFSFLHKLINKAKQAAGKA",
    "output": "Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 20 in the D-loop of several cytoplasmic tRNAs (acp3U(20))."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTELELLGPRASGQPLGTAILKAVAEDFQVDEVLDIPLSGQGEHLWLWVEKRDLNTEEAARRLARAAGVPVRSISYAGLKDRQALTRQWFSLHLPGKADPDLSRAEDATLRVLKQVRHQRKLQRGAHSANGFTLRLTALAADHAALDARLQTLKQQGVPNYFGGQRFGHGGGNVQDAQHWAARKALPEQRNVRSRLLSAARSYLFNQVLAARVADGSWQRAQVGDLLAFTDSRSFFSAGEQECSDPRLAILDLHPTGPMWGEGPSPAAGAALTLETAIGQQHALLCQWLANAGMSHERRILRLPIGGLTWHYPEPDILQLEFVLPAGCFATVVVRELVDLVPAGQTDSPCVF",
    "output": "Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTRPIQASLDLQALKQNLSIVRQAAPHARVWSVVKANAYGHGIERIWSALGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEMYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRVPVVTV",
    "output": "Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATYSFRQTTSSVAGGPCGRSLRLGGGSFRAPSIHGGSGGRGVSVSSARFVSSGLGSGLGGGYGGAFSSSFSAGFGGGYGGGLGSGDGLLSGNEKTTMQNLNDRLASYLDKVRALEEANSDLETKIREWYLKQGPGPARDYSPYYKAIEDLRDQILAATIDNSKVVLQIDNARLAADDFKTKFETEQALRMSVEADINGLRRVLDELTLARTDLELQIENLKEELAYLKKNHEEEMSALGGQVASQVSVEVDSAPGIDLSKILADMRDQYEHMAEKNRKDAEAWFHSKTEELNRELAVNTEQLQSSKSEVTDLRRTLQGLEIELQSQLSMKGALESTLADTEGRYGAQLAQIQDMIGSIEAQLAELRADMERQNSEYKMLMDIKTRLEQEIATYRQLLEGQESQLFGSLSGSPDKRDKPADGK",
    "output": "Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAIFEGSFTTASNLKVGIVVARFNDLITNKILSGCLDCLKRHGLDTSETSETLDIVWVPGSFELPIAAKTLLKKSNYDVLISLGAVIRGETSHYDVVISEASKGIAQVSYDYDVPIIFGVLTTDSMQQALERAGIKNNLGWNYALQAIEMGSLIKNLN",
    "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPIREIRHPLIRHKLGLMRRADISTKNFRELAQEVGALLTYEATKDLPLESYEIPGWCGPVQVEKIAGKKITVVPILRAGIGMLEGVLSLIPGAKVSAVGVARNEETLQAHTYLEKLVPEIDERLAMIIDPMLATGSSMVATIDLLKKAGCRDIRAMVLVAAPEGIAAVEQAHPDVTIYTASIDQKLNEHGYIIPGLGDAGDKIFGTKQKDS",
    "output": "Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKKNYIIGIDAGTTGIRTFCFNDKGKVISSAYQEFKQYYPKPGWVEHDPEEIWVKTQKLITLAIKNGKLNPKDAVAIGITNQRETSVVWDKKTGKPVYNAIVWQCRRTSDICKDLKKQSLDSNFRNKTGLVLDAYFSGTKIQWILDNVKGARDRAERGDLLFGTIDTWLLYKLTGHKEHKTDHTNASRTLLFNIQTKEWDEELCKILRVPMSMLPKAFNSKNLFGFTSNVKSIPDGIPISSLVGDQQGALFGQLCTEPGEAKNTYGTGCFLLFNVGDEFRISNQGLITTLALGPEGKTVYCLEGSVFIGGAVVQFLRDNLEFFKYSKDSEKLVKSIKTKDDIVFVPAFAGLGAPHWDQEARGAIFGLSRDTTPAQITRAALKAIALQSYELANAMEKETGKPLKFLRVDGGATSNAWLMQFQADILGTKVIRPQNVDTTVLGAAYLAGLERGFFKSVAHLRKEETKTTQFTPKMKESERKEEIDKWNLAISRVKTET",
    "output": "Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSATQDYIVADIGLADFGRKEIAIAETEMPGLMACREEFGASKPLKGARITGSLHMTIQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAIAASGVPVFAVKGETLEEYWTYTDKIFQWADGGVSNMILDDGGDATMYILLGARAEAGENILTNPGSEEEEILFAQIKKRLAATPGWFTRQRDAIKGVTEETTTGVNRLYQLQAKGLLPFPAINVNDSVTKSKFDNKYGCKESLVDGIRRGTDVMMAGKVAVVCGYGDVGKGSAASLSGAGARVKVTEVDPICALQAAMDGYEVVQLEDVVSSADIFITTTGNKDVIRIEHMRAMKDMAIVGNIGHFDNEIQVSALRNLKWTNVKPQVDLIEFPKGNRIILLSEGRLLNLGNATGHPSFVMSASFSNQVLAQIELFTKGEQYKNEVYVLPKQLDEKVARLHLAKLGAKLTELSEEQASYIGVKQQGPFKAEHYRY",
    "output": "May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MARTVHCIKLNKEAEGLDFPPLPGELGKKIWQSVSKEAWAGWLKHQTMLINENRLNMADARARQYLLKQTEKYFFGEGADQAQGYVPPQS",
    "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIRTLVHAKIHRATVTGADLNYVGSITIDEDLLEAAGIWPFERVQVVDVNNGARLETYAIVGERGSGTIQLNGAAAHLVNVGDLVIIMAYAQVDAKPEEWEPTVVFVNEQNAITEVKALLPVGGR",
    "output": "Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAARATTPADGEEPAPEAEALAAARERSSRFLSGLELVKQGAEARVFRGRFQGRAAVIKHRFPKGYRHPALEARLGRRRTVQEARALLRCRRAGISAPVVFFVDYASNCLYMEEIEGSVTVRDYIQSTMETEKTPQGLSNLAKTIGQVLARMHDEDLIHGDLTTSNMLLKPPLEQLNIVLIDFGLSFISALPEDKGVDLYVLEKAFLSTHPNTETVFEAFLKSYSTSSKKARPVLKKLDEVRLRGRKRSMVG",
    "output": "Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine . The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 . TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity). Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKDVRLGLDAREKMVEGINVLADAVKVTLGPKGRNVVLEKSFGAPTVTKDGVSVAREIELEDKFMNMGAQMVKEVSSQTNDVAGDGTTTATVLAQSIVREGMKSVAAGMNPMDLNRGIHKAVEAVVKEIQKMSVPCTTTESIAQVGTISANSDSAVGKMIAEAMEKVSTEGVITVEEGSSLHDELVVVEGMEFDRGYLSPYFVTNQEKMVAELDNPYILLHDKKISNIRDLLPTLEAVSKAGRPLLIIAEDVDGEALATLVINNMRGIVKATAIKAPGFGERRKAMLQDMAVLTGGTVISEEVGLTLENVTLDMLGETKSAVVGKDSTKLIDGAGAKADIEARCAQIRSQAENTTSEYDSEKLQERLAKLAGGVAVIKLGAATEVEMKEKKDRVDDALHATRAAVQEGIVAGGGVALVRARSKVKVKGDNDEQQLGIEIALRAMEEPMRQIAANCGLEGSVIVNKVMESKDNMGFDAASETYVDMIKAGIIDPAKVTRSALQNAASVAGLVLTTGAAIADLPSKDGASADAAAGGMGGMGGMM",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTVLHSIDFFSSSSAPVAIEARAPQSAFPEHHHDFYEIVIVEEGAGVHVFNGNPYTLSRGCVCFVRDHDRHLFESTDDLFLTNVLFRAPDAFRFLSGVGHFLPRECDGVYPSHWRVNGQVLQQIKCLIACLEHAPKSDQVEDIALHESVFMQLLVKLWQGCQTQAGDDQEGRLYQLLDWLQNNYSEAVEWPELADRFALPLRTLHRQLKNKTGMTPQRYLTRLRLLQARHQLCYSDNSVTDIAYLCGFGDSNHFSTLFKREFSQSPRDLRSQL",
    "output": "Activates expression of the rhaBAD and rhaT operons."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNATGAPGRNRGVDLQENNPASRSQCCSN",
    "output": "Protein transport. Probably involved in vesicular traffic."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTAGSDLDDFRGLLAKAFDERVVAWTAEAEAQERFPRQLIEHLGVCGVFDAKWATDARPDVGKLVELAFALGQLASAGIGVGVSLHDSAIAILRRFGKSDYLRDICDQAIRGAAVLCIGASEESGGSDLQIVETEIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNVAVVAVPAAQVSVQTPYRKVGAGPLDTAAVCIDTWVPADALVARAGTGLAAISWGLAHERMSIAGQIAASCQRAIGITLARMMSRRQFGQTLFEHQALRLRMADLQARVDLLRYALHGIAEQGRLELRTAAAVKVTAARLGEEVISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVAAGMTPDHDGYAAVVGASKA",
    "output": "Catalyzes the dehydrogenation at the alpha-beta position of ACP-bound acyl chains. This results in the introduction of a double bond in the lipidic chain, which is further transferred to the epsilon-amino group of lysine residue in the mycobactin core by MbtK."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPNVTLIGIDLGKNSFHIHCQEKHGNTLLRKRFSRIQLTQFLATCPPCIVAMESCAGAHFMARHISQLGHQVKLISPQFVRPFVKSNKNDFIDAEAICEATSRPSMHFVTPRTEDQQAMSALHRVRDALVRERVKATNQMHAFLLEFGISMPRGIAVIKRLATVPEEHELPPYLVRLLTRLHQHYGYLCEQIEEIERELKNHLADDETAQRLLTIPGIGTITASLLATKLGDGKNYLSSRDFGASTGLVPRQYSTGGKSTLMGISKRGDKNLRRLLVQCARVYMQRLEYQSGRLAEWVNGQLTRHHSNVVACALANKLARIAWVVTTQGTVFSK",
    "output": "Required for the transposition of the insertion element."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MILRRLVLAGSLLLATAFTSAKKADSPIITATRFDHEPINLFYFGDSDVVMLQDIKNGDVYVSRDAGVKWDMVNLDGLKGQALSLWSHPTDRTKAYILGKAGKHWVTNDQAKSWHEFSADVEFFQSLYPLVFHGKDSDRVLLQGQKCFGRDCKEVTYYTTDGFKTVDILMENARGCNWAVSTPIFGDGLNLSKEVNDRIFCIVPGLQSPWSDYNRLLYSDRFFKQDPGTEAPLDSGRAVSGVVRTASVKKYLLAAAKSARTSELALYVTDDGSQWHRAEFDGHRVEEDAYTVLESTNYSIQIDVVAETPSAPMGRLFTSNSNGTYFTRNIDHTNRNSLGFVDFEKIANIQGIILVNTVKNWEDVEMSALVEKKIISQISFDDGRTFQPLKAGKHDLHLHSVTHLSNSGRVFSSPAPGLVMGVGNTGGHLKDYYDGDLYVSDDAGITWRKALDEAHKYEFGDQGSVIVAIFDEGRTGKISYSLNHGKDWKEASLPDGIKIRARILTTMPDSTGLKFLLVGSAKKDSEVEHYVISISFTDMEERTCGKDDFETWPARLNEKNEPDCLMGHKQFYQRRKADVDCFIKKKFQEPVPQFEPCKCTVEDFECDFNFIRSTDGKSCVPARNLPVPEGACKKPDDKYMGSSGFRLIPGNACIREGGVELDKQIERVCTDTLTVPVSGEIAVQKTFFTADNYKGYFYLERKDSSKGDDETVIMITSELQIYITRDHGKIWKEIFPGESITRIVPHQYFDDVAYFLTNSGDGWYTLDRGENFRTFKVPIPPNQDKLPVLSFHPERRDWLIWTGAVECKTRGPQCHSVAYYSTNHGSEWHFLMQYVRRCEFIKREARGSSNNLVFCEQFENENPLNHHLQLLSTDDWFSEKKVHYNNILDFATMQEFIIVAVRGEKPQDSLSVGVSVDGETFAYADLPANVQIPVQRAYTVLESRTHAAFLHVTVNNIEDHEYGSILKSNSNGTSYVLSLSAVNRNTYGYADFEKMQGMEGVAMANVVGNVADVEKGAAKKYRTMITHNDGAEWTLLSPPSKDSEGRDYSCSTKGGKPTDKCALHLHSYTERVDPRDTYSSPAAIGVMLGTGNVGEYLTLKSEADTFITRDGGITWEEVKKDKYQWEFGDSGSIIVIVPESRPTKTLFYSLDEGKSWKEFQFSEVEMLIRDISTVPSDTSRNFLLWGNEVGNGKKPGIATVNVDFSNLKERHKQCVLNEEKPEADDYYLWEPIHPFQPNGCLFGHRAKYHRKRPDRDCFIGRELQHLDSIGDICECTRSDYECDYNYEPQIDGTCAPVPGLQPLDPKLICMEDPKAVEWYEPTGYRRIPLTKCEGGKQLHHIIPHACPNKEEEFLKKHPGLRGVGLFFVVMGPIGLAAAIGYYVYTRWDGKFGRIRLGDTGSGGFFASDSLFISIPVAIVAGVVAVATALPLLASSLWRSVKGYARVPGGSSSQRVYSSRAAFAAQRADYVGVVDDEDELLGAEDFDEEENDDRGQV",
    "output": "Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLRERIKKFHFIGIGGIGMSGIAQILLEMGYKVSGSDISENKNTKLLKQKGAKIYIGHRPENLGDAQVVVYSSAVKPDNPEIQEAKRRNIPVIPRGEMLAELFKLKEGIAVSGSHGKTTTTSMIAEILINAGLEPTVIIGGRLKRLGTNAKLGRGELLVSEADESDGSFLKLQPAVAVITNVDKEHLDFYENFERVKEAFEQFMNSVPFYGFAVVNLDDPTLAQLVKKSHERVITYGINSPALVRAKNLYLKEGRYEFGVEFKGKELGRIHLGIAGIHNVYNALAATGVALELGVSFEVIKKSLEEFRNAERRLELKGYYKNSPVYDDYGHHPTEIKAVINSLRDMYPDKNLLVVFQPHRYSRTYYLFEDFVKVLKDIDKLIVTDIYPASENNVYGVSAEELARKSGAVFAKDKEEVFEKVREVHDEGDVILFLGAGSISKWCEEFLKEVNLEK",
    "output": "Cell wall formation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSYNLTDPYEIARYIKEAKKSTPIKAYIEGDLSNCDFTNIEKFNSGDLYILFGESEEILVIIEKNKDKIKNCRIEQDRRKSAIPLLDMLKINARIEPGATIRDKVIIGENAVIMMGAVVNIGAEIGEGTMVDMNAVVGARGKLGKNVHLGAGAVVAGVLEPPSSDPCTIEDNVLIGANAVILEGVKIGKGSVVAAGSIVTTDVPENVVVAGAPAKIIKEVDVKTKDKTKLLDDLRK",
    "output": "Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDNKIVYVVSDSVGETADLVVRAAMGQFPFAPDIRRVPYVEDTGTLKEVISIAKSNQALICFTLVKPDMRQYLVTEAAKEGVEAYDIIGPLIDQIEEITGQVPRYEPGVVRRLDEEYFKKIEAIEFAVKYDDGRDARGILKADIVLIGISRTSKTPLSQYLAHNKRLKVANVPLVPEVDPPEELYQVAKEKCFGLKITPEKLNHIRKERLKSLGLSDGATYANINRIKEEIDHFENVVSKINCQVIDVSNKAIEETANIIVNAVQNQKMF",
    "output": "Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQSLSKEKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDALKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSTRGSPTRPNPPVRNLHQSGFSLSGTQVDEGVRSASKRIVAPPGGRSNITSLS",
    "output": "Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAQRRAAAESARHQRLLEGKAQAEGGSARTSLLILVSIFTIAAFLMFLVYKNFPQLSEEEGKCIKIPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYVFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSEQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSLFVLMILAILSILPALFQKKLKQKFE",
    "output": "Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes. Has phospholipid scramblase activity toward cholesterol and phosphatidylserine, as well as phosphatidylethanolamine and phosphatidylcholine. Required for autophagosome formation: participates in early stages of autophagosome biogenesis at the endoplasmic reticulum (ER) membrane by reequilibrating the leaflets of the ER as lipids are extracted by ATG2 (ATG2A or ATG2B) to mediate autophagosome assembly. In addition to autophagy, involved in other processes in which phospholipid scramblase activity is required (By similarity). Required for normal motor neuron development (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLSRRQLIPIATKSVSPFLRSSITCRRISMGRKELSEKDSNILDSVIRVDQAGELGANQIYKGQHFILQFTDPKVAPTIQHMWDQEKYHLATFDNYVLKNRVRPTFLRPFWDIAGFALGAGTALLGTKAAMACTEAVETVIGGHYNDQLRETAHLENKAPEFKEIRSHLAEFRDDELEHLNTAVEGWNAKEAPAHALLTNAIQMGCKAAIWMCKRF",
    "output": "Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSGEGDTTLKAICYKPGSLQLLDQRKLPLETIYLEIRDASDGWSAIQEMVVRGAPAIAIAAALSLAVEVFNFHGFDGSASDAVAFLENKLDYLVSSRPTAVNLADAALKLKHVIAKALATATEAKSIFKAYIEASEDMLEDDVVSNKAIGNFGLSLLRQQAKNPDKLSVLTHCNTGSLATAGYGTALGVIRALHTQGILERAYCTETRPFNQGSRLTAFELVHEKIPATLIADSAAAALMKDGRVDGVIVGADRVASNGDTANKIGTYSLALCAKHHGIPFYVAAPLTSVDLSLSSGKEIVIEERSPKELMHTHGGLGERIAAPGISVWNPAFDMTPAELIAGIITEKGVITKNGNDTFDISSFAKKITGNSSR",
    "output": "Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKIITQNKKAHFEYFIEQKFVAGIKLQGSEVKSIRAGKCSINEAYITFRNGEVFILNMHIAKFDASSIFNHEETRTRKLLLNRSEIDKLMGAQTRDGMTIIPLTVELHEGLIKVVIALAKGKKLFDKRETIKERDIKREQQQSLKGKMR",
    "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "VGFKAGVKDYKLTYYTPSYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEETQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLPGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIFKSQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKKHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGLFFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNDIIREASKWSPELAAACEVWKEIKFEFEAMDTL",
    "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKMAIACALLSSVVASSVWADAASSLKSRLDKVSSFHATFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQASDWQQYNIKQDGDNFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSAYQLKSQQNGAVDPSKFTFTPPQGVTIDDQRK",
    "output": "Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MASKLLLEIVTPDRKVLSQEVDYVGAPGIEGEFGIMANHIPFLSALGVGNLYFKEGNRTHYIFVSGGFAEVGNNKVTILAEVAEKAVEIDIARAQKAQEKAKARLAKAQDRIESARAQAALQRALARLTCKDAAQKAGTTTH",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKAPCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPMLRMKDGSYHKDGEFTPVSWEQAFDVMEEKFKTALKEKGPEAIGMFGSGQWTIWEGYAAAKLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAEMHPILWSRITNRRLSDPNVKVAVLSTFQHRSFELADNGIVFTPQSDLVILNYIANYIIQNNAVNQDFFTKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFDEYKAFVAEYTLDKTAEMTGVPKDQLEQLAQLYADPNKRVISYWTMGFNQHTRGVWANNLVYNLHLLTGKISQPGCGPFSLTGQPSACGTAREVGTFSHRLPADMVVTNEKHRDICEKHWQIPAGTIPAKVGLHAVAQDRALKDGKLNVYWVMCNNNMQAGPNINEDRMPGWRDPRNFIIVSDPYPTVSALSADLILPTAMWVEKEGAYGNAERRTQFWRQQIKAPGEAKSDLWQLVQFSRRFKTEEVWPEALLAQKPELRGKTLYDVLFATPAVSKFPLSELKEDQLNDESRELGFYLQKGLFEEYAWFGRGHGHDLAPFDDYHNARGLRWPVVEGKETQWRYSEGNDPYVKAGEGYKFYGKPDGKAVIFALPFEPAAESPDNEYDLWLSTGRVLEHWHTGSMTRRVPELHRAFPEAVVFIHPLDAKARDLRRGDKVKVSSRRGEVISIVETRGRNRPPQGLVYMPFFDAAQLVNNLTLDATDPLSKETDFKKCAVKLAKV",
    "output": "Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSATYAPDRILLEKAETLSEALPYIQRYAGKIFVVKYGGHAMGNPDAAQDFAEDIVLLKAIGIHPVVVHGGGPQIGKMLKALGVESQFIDGLRVTDNETAKIAEMVLSGAINKDIVSWIGRAGGRAVGISGKDAKLVEVEKVKKIRKNSTDGQDENIDLGFVGRPVSVDRRLIDTLTQSGMIPVVAPIGVGADGETYNINADTMAGALAAGLEAARLFLLTDVAGVLDADKKLLRTLTPSQIDSLTKADVISGGMIPKLETCIESVKSGVDAAVILDGRVPHSILIELFTEQGAGTLVKLD",
    "output": "Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSTLLEKTRKVNRILQKTGIQPVDFNEMASILKDVIEANVYILSRKGKVLGYSILKDYGNDIFAQSKIIPEEYNDKLLRVTETLANDKGNLFKEDKILSDLILTIVPVNGGGDRLGTLVLSRGVKEFTDDDLILAEYGATVVGLEILRSKNEEIEDEARKRAVVQMALGTLSYSELEAIKNIFEELNGKEGLLVASKIADKVGITRSVIVNALRKFESAGIIESRSLGMKGTHIRVLNDKLLEELEKMKR",
    "output": "DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAFMGRELKWGVAHIYSSLNNTIIHITDLTGAETVSRWSGGMVVKADREKPSPYAAMIAASRAAAEAMDKGITALHIKVRAPGGHGPKTPGPGAQAAIRALARAGFIIGRIEDVTPIPHDTTRRPGGRRGRRV",
    "output": "Located on the platform of the 30S subunit."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI",
    "output": "Required for insertion of 4Fe-4S clusters for at least IspG."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTTSVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSTSESVDAILEGMAWLGLDFDEGPFYQMQRMDRYREVLKQMQDAGLVYPCYMSTEELDALRERQREAGEKPRYDGTWRPEPGKVLPEPPAGVQPVLRFRNPLTGVVAWDDAVKGRIEISNEELDDLVIARPDGTPTYNFCVVVDDLDMRITHVIRGDDHVNNTPRQINILRALGGEPPVYAHLPTVLNEQGEKMSKRHGAMSVVGYRDAGFLPEAVVNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKSPAQYDHDKLAWLNAHYIKEADNARLAELAKPFFAELGIDEAALAQGADLAAVVGLLKDRASTVKEIAENAAMFYRTPAPDAESLAQHVTDVVRPALADLAAALKTVEWTKEAIAAALKATLGAHKLKMPQLAMPVRLLVAGTTHTPSIDSVLMLFGRDVVVGRIEKALV",
    "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTTILQINSAARSQGAQSTLLANELTAKLQQSNPGAKVVVRDLLADALPHLDESVLGAFFTPADKRTAEQNAIVAKSDALIAELQAADVIVIGAPMYNFGISSQLKTYFDWIARAGVTFRYTENGPEGLIKGKKVHVVTARGGKYAGTPNDSQTPYLRTFLGFVGMTDVNFIFAEGLNLGPDAQSAALAGAREAIAAA",
    "output": "Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVSVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGAYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPVAVEALSLIYNKDLVPNPPKTWEEIPALDKALKAKGKSALMFNLQEPYFTWPLIAADGGYAFKFENGKYDVKNVGVDSAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDKSKVNYGVTLLPTFKGKPSKPFVGVLSAGINAASPNKELAKEFLENYLMTDPGLEAVNNDKPLGAVAVKSFQEKLEKDPRIAATMANAQKGEIMPNIPQMSAFWYAVRTAVINAASARQTVDAALKDAQGRITK",
    "output": "Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLEIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTHIPRW",
    "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MISYPFFSLSPPGLVPPPMAVPPVEMYSGSFWNRMRKPLPLRTQVIRFTVVFVIVSFILAVALQITHERMPDPKVTKPLPDLGFELLTKVPGMYVLADCCIGFLNILSVFTAFKLYLLHRHCVGSGEPELPCNIPGVSRFFLSVWLCKENCRIELRNIHTIAWIRFITSYALLLLFRSAVIVMTSLPAPDDLCQDPPKIENPVKNVILTVLTAGGGSIHCGDLMYSGHTVILTLHLMFHWIYGAMVHWSFRPVVTVVAIFGYYCIVASRFHYTDDVLVAIYLTIATFIAVGHNADGAPWQLQLFIRWWPCCGANSREVTEDSQPVMVAFKSEELDEMNGVLEGRQKKHGGVGDGESLMFKCGAYV",
    "output": "Bifunctional sphingomyelin (SM)/ethanolamine phosphorylceramide (EPC) synthase with minimal inositol phosphorylceramide (IPC) synthase activity . Specificity is likely to be defined by residues in the lumenal catalytic domain that interact with the polar head groups of the phospholipid donors . SM is synthesized by both stages of the parasite life cycle, bloodstream forms (BSF) and procyclic forms (PCF), by transferring the phosphoryl headgroup from a 1,2-diacyl-sn-glycero-3-phosphocholine to an N-acylsphing-4-enine (ceramide) or an N-acylsphinganine (dihydroceramide) with release of 1,2-diacyl-sn-glycerol . Also catalyzes the reverse reaction, production of ceramide from sphingomyelin . EPC is synthesized by transferring phosphoethanolamine from a 1,2-diacyl-sn-glycero-3-phosphoethanolamine to ceramide or dihydroceramide by BSF and PCF, while IPC is confined to PCF . The ceramide/dihydroceramide ratios are skewed towards dihydroceramide in PCF parasites and ceramide in BSF parasites, this is likely due to differential expression and/or regulation of dihydroceramide desaturase, the enzyme responsible for converting dihydroceramide to ceramide ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEELQGYLEKDGSRQQHFLYPLLFQEYIYALAHNHGLNGSIFYEPVEVFGYDNKSSLVLVKRLITRIYQQNFLISLVNDSNQNRFVGYNHNNFFFSHFHSQMISESFAIIVEIPFSLRLVSYFEEKEIPKYHNLRSIHSIFTFLEDKLSHLNYVSDILIPHPIHMEILVQILQCWIQDVPFLHLLRFFLHEYHNLNSLLITQKKSIYVFSKENKRLFRFLYNSYVFEWEFLFVFIRKQSSYLRLTSSGTFLGRTHFYEKIEHLQIKHFVVVCRNYFHRTLWFCKDPFMHYVRYQGKAILASKGTHLLMKKWKYHFFNFWQYYFHVWTQPYRIHINQLSNYSFYFLGYLSSLLLNFSAVRNQMLENSFLIDTITKKFDTXVPVIFLIGSLAKAKFCTVSGHPISEPIWTDLSDSDILDRFGRICRNLSHYHSGSSKKQGLYRIKYILRLSCARTLARKHKSTVRTFLRRLGSGLLEEFFTEEEQVLSLIFPKTTPFILHGSHRERIWYLDIIRINDLVNHS",
    "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKIGIINTKIRTVFSAFACMIAASLVCTMPARAVVEININKGVIEPLPIAITDFLSADQLGSNITSVIAADLERSGLFAPIDKGAFIEKISNPDAAPRFEDWKVINAQALVTGRITKQPDGRLKAEFRLWDTFGGQQMIGQQFFTTPDNWRRVAHIIADAIYERLTGDKGYFDTRVVFVDESGPAQKRVKRLAIMDQDGANVRFISDGRALSLTPRFSPNRQEVTYMSFEGGSPKVYLLQLETGQRELVGNFPGMTIAPRFSPDGQKVVMSLLQDDGSANIYTMDLRNRTTTRLTSSQAIDTGASYSPDGSQIVFTSDRGGRPQLYVMGADGSNPRRISMGDGSYSTPVWSPRGDLIAFTKQSQGQFSIGVMKTDGSGERLLTSGFHNEGPTWAPNGRVLMFFRKAAGAGGPKLFTIDLTGRNERQIQTPNFASDPAWSPLLE",
    "output": "Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKTSMKAREAKRAQLVAKYAEKRLALKAIISSPATSEEDRWDAVLKLQALPRDSSAARQRNRCNQTGRPHGFLRKFGLSRIKLREATMRGEVPGLRKASW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSETHLSTQRFADLPLHPEVKQALAENGFEFCTPIQALSLPVLLQSKDIAGQAQTGTGKTMAFLVATFNHLLSTPVPEGRLINQPRAIIMAPTRELAIQIAKDAILLAKHTHLKVGIVYGGESYDVQRKVLDQGVDILIGTTGRIIDYVRQGIIGLNSIQAVVLDEADRMFDLGFIKDIRFLFRRMPEANQRLNMLFSATLSMKVQELAYDHMNEPVKVEIAPEEKTSKNIKEEIFYPSQEEKMRLLLTLIEEDWPEKAIVFSNTKHSCETLWSWLEGDGHRVGLLTGDVPQKKRIRILEQFTSGQLDILVATDVAARGLHISDVSHVYNYDLPDDCEDYVHRIGRTGRAGNKGMSISFACEEYALNLPAIESYINHSIPVSNYDSEALLADIPTPAKIHRKHPSGTRNLRDRSGTSRPGAQRSGARPPRHDRTRRHS",
    "output": "DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEDFVRQCFNPMIVELAERAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGYIEGKLSQMSKEVNAKIEPFLKTTPRPIRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYVVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDDCRNISDLKQYDSDEPELRSLSSWIQNEFNKACELTNSIWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRPCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR",
    "output": "Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MANPIRKLVDNSKKQLKKLNHIADKVEDYADEMAALSDEALQAKTPVFKEKIADALRDVTETDKQNKVLAKTLDALLPEAFAVAREAAKRVLGLYPFRVQIMGAAVLNDGNLAEMRTGEGKTLTATMAVYLNALTDRGVHVVTVNDYLSARDAEQMGQLYNWLGLSVGVNVGDAPAEEKRAAYDADITYSTNFNIGFDYLRDNMVRRAEERVMQRGLNFALIDEADSILIDTARTPLIISGPGSGVSQLYGRADRFVKTLQQDEDYKIDEEAKTTMLTNDGIHKGEIFFNLDNLYDAGDTALTHHIDQALRANFNYINDKDYVVQDGEVKLIDQSTGRISEGTRLSDGLHQAIEAKEGVEIQEENKSMAQITYQNLFRMYKKLSGMTGTAKTEEEELREIYNMEVITIPTNRPIKRVDYPDLLYPSIRAKYNAVVKLIQELHEKGQPILIGTGSVESSELLSKILMAQNVPHNVLNAKNNAKEAEIIANAGQRGAVTVATNMAGRGTDIKLGPGVADLGGLAVIATERHESRRIDNQLRGRAGRQGDDGFSQFFLSLEDDLMIRFGAERIRAVWERMNLDEEETVIKNRLITRSVESAQKRVEGNNYDTRKNVLQYDDVVREQRELIYHQRDIIIDESQSLDWVLMPMVSRTINRVVTVQTKSKKPSEWQLQQIIVFAENVLVNEGALTENDLSGLSREDIEAKLYALAKENYANKKRQLYEPEQMLEFEKVVILRAVDQHWTDHIDALDRLRQGVGLRGYGQLNPLIEYQNEAFENFNKMIADVEYDATRTFMKAEIRQNLKA",
    "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSQGKIVQIIGAVVDVEFQRNEVPKVYHALKVEGTAITLEVQQQLGDGVVRTIALGSTDGLKRNLLATNTERAISVPVGAGTLGRIMDVLGRPIDEAGDVQASDHWEIHRAAPSYEDQSSSTELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEYFRDEKDASGKGKDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKSGSITSIQAVYVPADDLTDPSPATTFAHLDSTVTLSRNIASLGIYPAVDPLDSTSRQMDPLVIGHEHYDTAQRVQQTLQKYKELKDIIAILGMDELSEEDKQSVSRARKIERFFSQPFHVAEVFTGSPGKYVSLKDTIRGFKAICDGEYDHLPEQAFYMVGSIEEAVEKANKMSAKA",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MINFSSFYQQIADSNLQHWLETLPAILGKWQREHKHGNLPKWEKVLNKLHYPSPDSVDLVDSVTIGTGEQLTPGEKEKLENLLRLFMPWRKGPFHIHGIHIDTEWRSDWKWDRVKPHISPLQNRTVLDVGCGSGYHMWRMLGAGAKRVVGIDPSPLFLCQFEAVKRLSGENHPVHLLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRMGGELVLETLVIDGDENAVLVPQDRYGKMNNVWFIPSVAALMLWLKKCDFTDIRCVDTDVTALAEQRRTDWMPNESLVEYLDPKDITKTVEGYPAPKRATIIAVKNQPNQDLS",
    "output": "Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTQETLKSDIKALLKERNAVLLAHNYMRDEVQEIADITGDSLALSIEAAKTDADVIVFCGVHFMAESASILAPEKTVLLPRLDAGCPMADMVSVEALREMKAKLPGVPVVTYVNSSAAVKAESDICCTSANAVKVVQSMSEKEIIFAPDRNLGSYIARFTDKKFHLWEGYCPTHERLRPEVVKELKQANPDAPFVCHPECNPKVVELADHVCSTTGMYDYCKKSGAKRFIIGTEAGILWRLKRESPDKEFILASPALICPNMKLTSLEDVFEALQQMTPVVKVTEEIRIPAKRALDRMLAIPRD",
    "output": "Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFAITGGGTGGHLAIAKALAQEAQKNNQQSIYIGSQIGQDKTWFEGSSLFTHCYFLDSTGVVNKKGLGKIKAIFKQLKAAWEARNILKKHKIEYVISVGGFSAGGASIGAILSNTPLFIHEQNAIKGKLNEILTPFAKAIFGSFEGKSKNFIHTSYPVRDEFFTHSRVREKLHHLLFLGGSQGAKGINDFALQIVPELLKRGITIAHQCGERDFERIKKAYEHIGILDKVDVFAFDKEIVLRLQKADLCIARSGASSLWEMSANGLIGIFVPYPYAAKDHQYYNALHFTKQGLGLLLRESQLDMLRVFTFIESLQKQEDSLSEKSHLLMSKIQPNGAKEILEHITSLMSH",
    "output": "Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKFGKDFRSHLEETLPAWRDKYLAYKSLKKLIKNLPPDGDPPPVAAAAEVPAGDGDGDGGIALGNWFARVLDMELQKLNDFYIEREEWYVIRLQVLKERIERVKAKKNGAFTSKSEFTEEMLEIRKAFVIIHGEMILLQTYSSLNFAGLVKILKKYDKRTGGLLSLPFTQRARHQPFFTTEPLTRLVRECEANLELLFPIEAEVLESASSSAKLQPQNDDAASHDPASSVDVETSDVYRSTLAAMKAIQGLRKASSTYNPLSLARFFHGEDGEACSGAITSESDSYSDSQIEDAEDDDKEVQSREQNTAQNAAEGQPRDE",
    "output": "Inositol polyphosphate sensor that associates with transcription factors to regulate Pi starvation responses (By similarity). The SPX domain provides a basic binding surface for inositol polyphosphate signaling molecules (By similarity). Interacts with PHR2 to inhibits its translocation to the nucleus and repress its DNA-binding activity, and then negatively regulate Pi signaling (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MHLITQKALKDAAEKYPQHKTELVALGNTIAKGYFKKPESLKAVFPSLDNFKYLDKHYVFNVGGNELRVVAMVFFESQKCYIREVMTHKEYDFFTAVHRTKGKK",
    "output": "Toxic component of a type II toxin-antitoxin (TA) system. A probable translation-dependent mRNA interferase."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDLSNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNLPIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAITTVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLGSTIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVKGWVSAKLQ",
    "output": "Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAKIRQNDEVIVLTGKDKGKRGKVTKVLPNGKVFVEGINIITKHEKPVPALGKAGGLVKKEAAIDASNVAIFNPKTNKADRVGFRFEDGKKVRFFKSNNEII",
    "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVKVTDIVLWDKPGEKVLLLGNQAIVRGALEGNIGVYAAYPGTPSSEITDTMAMVAKKAGVYMEYSTNEKVAFETALSASWAGLRAMTAMKHVGLNVAMDSFMTVSYMGINGGLIVVVADDPSMWSSQNEQDTRAIAKFANIPVLEPSSVQEAKDMVKYAFEISEKYGQMVILRTTTRSSHMRGDVVLGELPQEIKEGKRKFGNFKKNPEKYVDIPAFQRPKHPWLLETIEKFREEFNTSPFNWIEGPEDAKVGIIAPGLSYAYVKEALAWLGIDNVKILKLGTPFPVPYGLLEKFFNGLERVLIVEELEPVVEEQVKVWAFDNNINIEIHGKDLVPRVYEMTTRRAVEAVAKFLGVETPINFQEIDEKYKKVQEMVPPRPPSLCPACPHRNTFFAIRKAATPRAIFPSDIGCYTLGVLPPLKTVDTTIAMGGSIGVAHGLSIALNGALGEEQRKTGKEKKIIVATIGDSTFFHTGLPALANAIYNRSNVLIVVMDNMVTAMTGDQPNPGTGETPHGPGKRILIEEVARAMGADFVAVVDPYDIKETYETIKKALEVEGVSVVVSRRACALYRIGQLRREGKQWPIYQVNEEKCTGCKICINAYGCPAIYWDAEKKKARVDPLMCWGCGGCAQVCPFGAFEKVREGEL",
    "output": "Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRVDGREVRELRHVHIHTNYLKHPEGSVLIEVGDTKVICSATVEERVPPFMRGEGKGWVTAEYAMIPRATEQRTIRESSKGKVTGRTMEIQRLIGRALRAVVDLEVLGERTVWIDCDVIQADGGTRTASITGAYVAMVLAFEKLLQAEKVTKIPVKDYLAATSVGILEEQGVVLDLNYAEDSKADVDMNVIMTGKGHFVEVQGTGEEATFSRAQLNELLDAAEHGILQLIEKQKEALGDIVSHIE",
    "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTTSPVKVLIHGASGRMGKALLRLAAEDDALHVVGAVVGRSPSQRVVDGVPYFAANELGGAPAFDVAIDFSLPQGFAPILALCVQRGKPLVSGTTGLDEAQRAGLLQAAGQIPLVWASNFSLGVAVLTELVERAAGSLPGWDCDIIEAHHVHKQDAPSGTALTLGEAATGSGAQPRFASVRAGDIVGEHSVQFTGLGERVELIHRATNRDIFARGALHAAKRLLGKPPGSYRVRDLVL",
    "output": "Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSNSRMNGVEKLSSKSTRRVANAGKATLLALGKAFPSQVVPQENLVEGFLRDTKCDDAFIKEKLEHLCKTTTVKTRYTVLTREILAKYPELTTEGSPTIKQRLEIANEAVVEMALEASLGCIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGADPRECEAPFMELHYAVQQFLPGTQNVIEGRLTEEGINFKLGRDLPQKIEENIEEFCKKLMGKAGDESMEFNDMFWAVHPGGPAILNRLETKLKLEKEKLESSRRALVDYGNVSSNTILYVMEYMRDELKKKGDAAQEWGLGLAFGPGITFEGLLIRSLTSS",
    "output": "Plant type III polyketide synthases (PKSs) that catalyzes the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array of natural products including long-chain alkyl alpha-pyrones. Accepts up to C(20) chain-length fatty acyl CoAs as starter substrates, and carries out sequential condensations with malonyl-CoA to produce triketide and tetraketide alpha-pyrones, potential sporopollenin precursors . Favorite substrates for are midchain- and v-hydroxylated fatty acyl-CoAs (e.g. 12-hydroxyoctadecanoyl-CoA and 16-hydroxyhexadecanoyl-CoA). Required for pollen development and sporopollenin biosynthesis, the major constituent of exine in the outer pollen wall . In vitro, can use 4-coumaroyl-coenzyme A as substrate to produce bis-noryangonin and fatty acyl-coenzyme A as substrate to produce medium-chain alkyl pyrones. May play a role in both the synthesis of pollen fatty acids and phenolics found in exine ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTPGCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDEDHQVCEQFGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFDDFKTSNHHDVVLNWLKEHA",
    "output": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKLAVIAGDGIGPEVIGEALRVLDAVVPGVEKTEYDLGARLYHRTGEVLPDSVLDELKGHDAILLGAIGDPSMPSGVLERGLLLRIRFELDHHINLRPGRLYPGVQSPLAGNPEIDFVVVREGTEGPYTGNGGAIRVGTPHEIATEVSVNTAYGVRRVVQDAFKRAQQRRKHLTLVHKNNVLTNAGSLWWRTVQAVAAEYPEVEVAYQHVDAATIHMVTDPGRFDVIVTDNLFGDIITDLAAAVCGGIGLAASGNIDATLTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAHMAEIDAAARVDKAVAEHLATRGDEKLSTTQVGDRILGKL",
    "output": "Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSDILNVSQQREAITKAAAYISAILEPHFKNTTNFEPPRTLIICGSGLGGISTKLSRDNPPPVTVPYQDIPGFKKSTVPGHSGTLMFGSMNGSPVVLMNGRLHGYEGNTLFETTFPIRVLNHMGHVRNLIVTNAAGGINAKYQACDLMCIYDHLNIPGLAGQHPLRGPNLDEDGPRFLALSDAYDLELRKLLFKKWKELKIQRPLHEGTYTFVSGPTFETRAESKMIRMLGGDAVGMSTVPEVIVARHCGWRVLALSLITNTCVVDSPASALDESPVPLEKGKATHAEVLENGKIASNDVQNLIAAVMGEL",
    "output": "The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine and inosine (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVSTISRQDQNNNDDLNQPSKEGRFGKYGGQYVPETLMPALFELEEAASDAWKDKQFVNELNHLLKTYVGRETPLYEAKRLTEHYQTKTSTSRIWLKREDLNHTGAHKINNALGQALLAIRMGKQRIIAETGAGQHGVATATVCARFGLQCIIYMGAEDIKRQSLNVFRMKLLGAEVKVVTSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPMIVRDFHAVIGEEAKKQCLESFGSLPDILLACVGGGSNAMGLFHPFVKEKSVRLIGVEAAGSGVNTEKHAATITKGSVGILHGSMSLLLQDKDGQVQEAHSISAGLDYPGVGPEHSYLKDIGRAEYGSVTDAEALDALKLVSELEGIIPALETAHAFAWLEKLCPTLDKDTEIVINCSGRGDKDVNTVASSLNID",
    "output": "The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MARTTSQLYDAVPIQSSVVLCSCPSPSMVRSQTEPGSSPGIPSGVSRQGSTMDGTTAEARPSTNPLQQHPAQLPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYHFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFETITWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGFMQVSSSSSSHSLSTVETSLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQQYQSNPDAAVQ",
    "output": "Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2 and RPS6KA3), cyclic AMP-dependent protein kinase (PRKACA), protein kinase C (PRKCD and PRKCZ), serum and glucocorticoid-inducible kinase (SGK1, SGK2 and SGK3), p21-activated kinase-1 (PAK1), protein kinase PKN (PKN1 and PKN2). Plays a central role in the transduction of signals from insulin by providing the activating phosphorylation to PKB/AKT1, thus propagating the signal to downstream targets controlling cell proliferation and survival, as well as glucose and amino acid uptake and storage. Negatively regulates the TGF-beta-induced signaling by: modulating the association of SMAD3 and SMAD7 with TGF-beta receptor, phosphorylating SMAD2, SMAD3, SMAD4 and SMAD7, preventing the nuclear translocation of SMAD3 and SMAD4 and the translocation of SMAD7 from the nucleus to the cytoplasm in response to TGF-beta. Activates PPARG transcriptional activity and promotes adipocyte differentiation. Activates the NF-kappa-B pathway via phosphorylation of IKKB. The tyrosine phosphorylated form is crucial for the regulation of focal adhesions by angiotensin II. Controls proliferation, survival, and growth of developing pancreatic cells. Participates in the regulation of Ca(2+) entry and Ca(2+)-activated K(+) channels of mast cells. Essential for the motility of vascular endothelial cells (ECs) and is involved in the regulation of their chemotaxis. Plays a critical role in cardiac homeostasis by serving as a dual effector for cell survival and beta-adrenergic response. Plays an important role during thymocyte development by regulating the expression of key nutrient receptors on the surface of pre-T cells and mediating Notch-induced cell growth and proliferative responses. Provides negative feedback inhibition to toll-like receptor-mediated NF-kappa-B activation in macrophages."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVSTATQIAGFNFDNCLMNAAGVYCMSKEELLEIETSAAGSFVTKTGTLEAREGNPEPRYAPTPLGSINSMGLPNMGYDYYLDVVLDLEKEENSKNHFISVVGLSPEDTHTILKTLHSSAYQGLVELNLSCPNVPGKPQIAYDFETTEQLLTEIFSYYTKPLGVKLPPYFDIVHFDQAAAIFNKFPLAFVNSVNSIGNGLVIDDETVIIKPKNGFGGIGGDYIKPTALANVHAFYQRLNPSIQIIGTGGVKSGRDAFEHILCGASMVQIGTALQEEGPEIFTRITEELKQIMVEKGYQRLDDFRGKLHYLD",
    "output": "Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTFLSTSAFSPLAFSLGLLLVVATAFPTPGPLGGDATSNRLPLTSADKMEELIKYILGKISALKKEMCDNYNKCEDSKEALAENNLNLPKLAEKDGCFQSGFNQETCLTRITTGLQEFQIYLKFLQDKYEGDEENAKSVYTSTNVLLQMLKRKGKNQDEVTIPVPTVEVGLQAKLQSQEEWLRHTTIHLTLRRLEDFLQFSLRAVRIM",
    "output": "Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSAPDSHAPLSRPAVAKSWRGRLELGFERHGARTTLAHRLHDGPLRVQRPLYPEGDAICHAVIVHPPGGVAGGDRLDIDIALGDGTHAVLTTPGATKWYKSNGLDATQRIGIAVGPHAKLDWLPQNNLFFDAAHAALDFTVTLGEGASAIGWDATQIGRQAAGETWAAGRIASTSALVAADGRPLWTERALLDARDPLRGALQGLAGFPAYGTPWAAGAACDAALAEALAARMPFDDTLRAAATCVTPGVVLVRAISTSMEALQRHFTDCWLRLRPIVHDVDARPLRLWQT",
    "output": "Required for maturation of urease via the functional incorporation of the urease nickel metallocenter."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLPHGLIVSCQALADEPLHSSFIMSKMALAAYEGGAVGIRANTKEDILAIKETVDLPVIGIVKRDYDHSDVFITATSKEVDELIESQCEVIALDATLQQRPKETLDELVSYIRTHAPNVEIMADIATVEEAKNAARLGFDYIGTTLHGYTSYTQGQLLYQNDFQFLKDVLQSVDAKVIAEGNVITPDMYKRVMDLGVHCSVVGGAITRPKEITKRFVQVMED",
    "output": "Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKILVGNDDGIFAPGVRALANTLAPDHEVTVVCPDRERSATGHGLTIHQPIRAEQVQSMFVDQVTAWACSGTPADCIKLALGALLDSPPDFVLSGINQGPNLGTDVLYSGTVSAAMEGVIEGITSIAFSYSSFTDQQFQPAANFGQQLLEHLIQHPLSEPMLLNVNVPAVPADQIQGVALTRQGIRRYHDLFEKRIDPRGKTYYWLAGEVMEDLEDDRMADPFVLTDVQAIRQRCIAITPLQYNLTANNSLNPLLAWLTPLQKRQSVI",
    "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MESPRGRPGPETDLLALGEQQAAIFGDGPGQTPSERPSDLRLSEDEEAENVGGASCHPKASLKTSSCSFVHPPEWEAPEDKPGRGGTFSGAGSRLGAPDPEFDLHGSSRRKDPEPPEAKPESERVCRRGSPVGGGMDVEQKEDDNEAAEAGRGGRSFSSRLQDSRSLDGLSGACGGPASSGGAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPQPPPPAPTRPCSAPTPTPAIPPIDPDVLRDLERLSRELGGRVDRLLRGLGGAVQELTALSVGCIQTYRDAVDSLGEAVDMSIKGMYTLLARCEELERALQPVQGLARQVRDIRRTLEVLEALCK",
    "output": "As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMSERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH",
    "output": "Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFSSESVTEGHPDKICDQISDAIVDALLTADPLSRVAAEVVVNTGMVILTGEITSQAHVNFTRLVRDKVAEIGYTDAKNGFSAESCAVLVAFDEQSPDIAQGVNLALESRTSQEDEFDLIGAGDQGLMFGFACDETPELMPLPISLAHRLSRQLAAVRKNGTLPYLRPDGKTQVTVAYEEGRPVGIHTLLISTQHTPTIGAITEEAAVQERIRADLWEAVVQPVFAELPIKPDGNTRFLTNPTGKFVIGGPQGDAGLTGRKIIVDTYGGYSRHGGGAFSGKDPTKVDRSAAYAARYVAKNIVAAGLAQKCEVQVSYAIGVARPINLLVETFGTGRIPDEALLRLVQRHFDLRPAAILAQFQLRELPRQRGGRFYQNVAVYGHFGQTHLDLPWERTDKAALLREEAFAGATAILG",
    "output": "Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG",
    "output": "Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVTQLTKNAIDSLINSTNPDEQYVIQVLKAPQSVAENLFKICISDGFCKFKKGYFVSDAATKCQDLKDLCIIKCKKYIDDSNHDKERIIISNYELIYSNIQEQIGKPIEYKQYKSSGFSNPEGSTVIPSQYLSRNAQILQQNQVSQPKQMVTPPVSNINKPTPAVNNTFAQKPAVTNQNIQRVNQNPQQMNKTAPVKQNNNNNNNNNGNNKNNSSLQISTDGDEQNLEYIRNLQPNGQPQTIKVRITKKGDLKSFKEKQGKLFSIDVIDKFGDECSISFFNEIAEQYDGLFKVGQVIVLKQFSVKVNNNHQYNKGDHTVTVNKESKILICQEDPSIPMIKLNRQFIQDMQNKQKGDLIDLIVVVKADTEVKTMILKKDNQQQSKRDIISFDESLIETEITLWGETAKDYDAKQGDIIVFKDAKIGEFKDKKQINIGYGTQIFMNPDEQLFPQIHDVKKWYLSLNSDQLSTIQKAQGNDTGPREVTSFESSLNILKEEIKNLQTDPEMKIWKEIRGQIMYIKDTPLYYNACFSCKKKIARNNEVWTCINCNKDFNEPDSRYILSLNISDSTDTIWVSAFDEVGQKILGVKGDVFRYADEDTEHGTETKKKLLMAAQNKEYRFLLLTKQERDQNGNARDKTVIHAIKDFQPAYEAKKIINSLEKFMVIEENNP",
    "output": "As part of the heterotrimeric replication protein A (RPA) complex, binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress (By similarity). It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism (By similarity). Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage (By similarity). In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MFTGSIVALVTPMDEKGNVSRSCLKKLIDYHVANGTSAIVSVGTTGESATLSHDEHGDVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPTQEGLFQHFKAIAEHTDLPQILYNVPSRTGCDMLPETVGRLAEIKNIIAIKEATGNLTRVHQIKELVSDDFILLSGDDASALDFMQLGGHGVISVTANVAARDMADMCKLAAEGQFAEARAINQRLMPLHNKLFVEPNPIPVKWACKALGLVATDTLRLPMTPITDHGRDIVKAALQHAGLL",
    "output": "Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIESKNQSFFPNRFDCVVVGAGHAGSEAAYIASKGGAKTLLITMNLDTIGQMSCNPAIGGIAKGHMVREVDALGGIMGKVIDNTGIQFKMLNTSKGPSVWAPRAQAEKKEYQLKVKHTLEAEKNLSMRQDTVEELLIENDQVIGVKTGRGFEIYTNHVILTTGTFLSSLVHIGTYQNENGRMCEPTVKGLSKSLAKYNLKLGRLKTGTPPRIHKNSVDLSVLAIQDGDANPSPFSFSTEKITRRQIPCYITYTNVETHKLIHENLSLSPMYSGQIQSTGPRYCPSIEDKVVRFADRERHQVFLEPEGYETTEIYLNGVSTSLPEEVQWKLVRSLKGLENAEIVRPGYAIEYDYVDPTELKPTLETKKIKGLYHAGQINGTTGYEEAAAQGLVAAYSVLHSLKNLDPLLFKRSESYIGVLIDDLVYKGVEDPYRMFTSRAEHRLLLRQDNADQRLMKYGYELGLVDQESYDRMKDKYERVNSVREKIYQIPLKPSDEFQNLLDQKGITNYKFGMKLDSFLKRPEIKIEDVEFMLPEVSSWSESEKNILEMEIKYEGYIKRELETIQWKNKYLDLAIPEDINYESIAGLKKEAIQKLKTHKPMTLEKAGQISGVDPSDVDLLLYHIKGKRKQEAEAS",
    "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLIEHERGFVLHVRAWRETSLLVEVLTEQHGRVGLLARGVHGPRKQALRAALQPLQLIQFSAVQRGELAQLRQAEALDTAPRLVGDTMLAGFYISELLLRLAPRNDPVPELYACYTQARTHLAADLPLAWGLRRFERDVLEGLGFAFDLQHDSDGQPIDPAARYRLDPEEGALRVLSERLAQDRRETVTGAALLALGEDVMPAAEDMPGLRRSMRSVLLHHLGGRGLKSWEMLEDLARRR",
    "output": "Involved in DNA repair and RecF pathway recombination."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNIDNELSKCRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHEGAASMDWMEQEKERGITITSAATTCFWNGHRINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRICFMNKMDRMGADFYRCVDMLVDRLGATPLVLQLPIGSEKDFVGVVDLLEMRSIIWDEDSLGASFHYGEIPKDMIDKAQEYRNKLLESAVELNDEAMNLYFEGKEISVSLLKSCIRTGVIQSKFVPVLCGSAFKNRGVQPLLDAVVDFLPAPNDIPVIEALDVKTSNTINVKTSAGGKFVALAFKVMTDKFVGSLTFIRIYSGKLSSKTTVLNAVKDSTESIGRILLMHANNREDITEAQAGDIVALAGLKKTVTGDTLCALDYPVILERMEFPEPVMEIAVEPKSTADQEKMGIALSRLVAEDPSLGMYVNPESGQTILKGMGELHLEVIVDRMRREFNVEANIGAPQVAYRETITKSVEIEYIHKKQTGGAGQFAKVNILFEPLPPGSGFQFESKITGGAIPKEYIPGVQSGLENIRGSGMLAGFPVIDFKATLFDGAFHEVDSSPLAFELAAKGAFRDMVNKAGAILLEPIMKVEIITPDEYMGDVIGDINSRRGRVAEMQDRHNTKVILAFIPLAKMFGYVKDLRSMSQGRAQYSMYFSCYEQVPDNIVANEIKTK",
    "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFQSSIYNKNYKKFLKNLKYQGEYAVTLGILAISILLLTGFNQFLNTKPTLKKNYFLNQKSIKNTLKNWNDIIATTANKYKVDEKLIKSIVYVESSGNPYAKSQSNAIGLMQIKPSSAGAEVYRLNGKKGRPSIQELYDPKTNIDIGTSYISFLQKKFISIKNKDVMRYAIIVAYVNGTSALLKTFSKSRKEAINIINTMTKKSFCTHIKKNTRQCKHFVI",
    "output": "Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDSSTVLFIGAVAVAFIFLKWMVSPIPPQNEFTIDHLSQDQSTGSTTSSNAHQNRDTHSISTQSHRNSRRAVSESMIEVVQSIAPMLTVEQIRYDLETTGNVEATVNRFMELGDLPFPPGYVRPQQPPTPSEEPKKQEVIGKRSVNLLEKYNIDAKNPKSDHNSLLHQRRQEMILGARKRLAAQLSNEL",
    "output": "Component of the endoplasmic reticulum-associated protein degradation (ERAD) pathway. Recruits the soluble ubiquitin-conjugating enzyme UBC7 to the cytoplasmic face of the endoplasmic reticulum membrane where it functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system. Targets the E2 conjugating enzyme UBC7 to the DOA10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains, and to the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M) (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAILKDTIIRYANARYATASGTSTATAASVSAASCPNLPLLLQKRRAIASAKSKNPNLVKRELQAHHSAISEYNNDQLDHYFRLSHTERPLYNLTNFNSQPQVNPKMRFLIFDFIMYCHTRLNLSTSTLFLTFTILDKYSSRFIIKSYNYQLLSLTALWISSKFWDSKNRMATLKVLQNLCCNQYSIKQFTTMEMHLFKSLDWSICQSATFDSYIDIFLFQSTSPLSPGVVLSAPLEAFIQQKLALLNNAAGTAINKSSSSQGPSLNINEIKLGAIMLCELASFNLELSFKYDRSLIALGAINLIKLSLNYYNSNLWENINLALEENCQDLDIKLSEISNTLLDIAMDQNSFPSSFKSKYLNSNKTSLAKSLLDALQNYCIQLKLEEFYRSQELETMYNTIFAQSFDSDSLTCVYSNATTPKSATVSSAATDYFSDHTHLRRLTKDSISPPFAFTPTSSSSSPSPFNSPYKTSSSMTTPDSASHHSHSGSFSSTQNSFKRSLSIPQNSSIFWPSPLTPTTPSLMSNRKLLQNLSVRSKRLFPVRPMATAHPCSAPTQLKKRSTSSVDCDFNDSSNLKKTR",
    "output": "Essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAEEEVAKLEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSESFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLAVQHITVSSDQSVNPFEDVPVVNGTSFDENSFAARLIQRGSHTDAPDTATGNCLLQRAAGAGNEAAALFLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPGYPLDKPDADGSTVLLLAYMKGNANLCRAIVRSGARLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLGGVS",
    "output": "Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSFLSGFFGPICEIEVVLNDAETRKVSEIKTEEGKVEKHFLFYDGESVAGKVNIVFKQPGKRLEHHGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRNYDFEFMQVEKPYESYIGSNVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETVAKYEIMDGAPVKGESIPIRLFIAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIVLWRKAPEKIKKRTNFHQRFEPQEPQASAEEPEI",
    "output": "Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIGKLTGTLLEKNPPEVLVDCHGVGYEVQVPMSTFYNLPAVGERVQLLTQFIVREDAQLLYGFGSAPERQAFRELIKISGVGPRTALSILSGMGVDDLAQAVSLQEAGRLVKVPGIGKKTAERLLLELKGKLGVDIGARPEAANDAQADILQALLALGYNDKEGTAALKALPKDVGVSEGIKLALKALAK",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAPRIERHTGPEEDREEEIHSHQSPSVSGDDDGVEISERPPKRRRLSDSESSEDDPFVPQQPLPTLSRIKKKSDLSAAKGPDRNADQPDPVTAKDAFAMGLQSMDSSFSSLGLAPWLVGSLSAMAIRRPTAIQRACIPEILKGRDCIGGSRTGSGKTVAFAAPILHRWSEDPFGIFAVVLTPTRELALQIFEQFKAISAPQSLKPVLITGGSEMRPQAIALSTRPHVVIATPGRLADHIKTSGQDTIYGLNRVRMVVLDEADRLLASGPGSMLPDVETCLSALPPSTSRQTLLFTATVTQEVRALKSMPRPKDRLPIFVTEISTENNTTIPPTLKQCYLQVPMTHREAFLHVLLSTDANSSKPAIIFCNRTKTADLLDRLLRRLGHRVTSLHSLLPQSERTSNLARFRASAARLLVATDVAARGLDIPSVGLVVNFDVPRNPDDYIHRVGRTARAGREGEAITLVGQRDVQLVLAIEERVGRQMVAWEEEGVSIEGRIVRGGLLKDVGGAKREALGEIEEGRDVLGRRVRKLKKTR",
    "output": "ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLLFLVCFVCNIWSVFGVQAASNVSDVVNTIVVASRTQRDISMLVPIGQTNNMGVSLNTVLFEKVGYNSSSLDYIRQLLDGGLQTWMLDLYYNNATSNWQLCPAPFPQNSSTNAYETRTVRWNNRDYHCQPSFTLDSVMQEFRSYFMSTNTNIAVNLIQIMFNLYDFDFSESKNKTIASKELKNYATFSNYGNSTLNSSLSSVSDMLYTPQDLTTYQKTQSGTGISAFYNTSAFDFPSSQTFLLNDYKRLITYVAENKVPKSALGSNDENTIFFNEDFADISYTSDESLLERCGSRTLSDFNQLSLNSNFRTVVDNENVPFTPSSFRKYVTCGYSPILNASRYSIPNKPATTDISDILTYYFPRSYWSWAPGQPHDRQHTANTSSFDKRDYKSSDNQMARKCVTLQESGFVLSNCYEEHKFACQKFNSPNEWKISVSSDTYFSDDYGDCPEGYSFNVPQSSIEVDSLRQEVANSGEKYPIWVDLNDITVANCFVTGGPYAQCPYQRTVSGRRLVELIAPSFVVASVIVVLIFIEKIFRVNPVQTNRKRYWRRAINEYNKQHGYEGVPS",
    "output": "May be involved in telomere capping."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRRKIIAANWKMYKTCAETESFIKEFKELSKGYEEKEIVICPPFTSLYVANKLLEDTPIKLGAQNMFWEKEGAYTGEISPIMLKDLNCSYVIIGHSERRQYFSETNDMINKKLKSAFEYELIPIFCVGEKWEEREKGKTEEVITEQVKKGLQGLEKEKVEKIVIAYEPVWAIGTGHSAKGEDANEVAKLIRRIISEIYDEEVSQKVRIQYGGSVNPQNIKEFLAQSEIDGALVGGASLKPQSFWDIVRS",
    "output": "Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKELTFEQQARAKLLEGINKLAKAVKITAGPKGRNALIEKKYGAPLIVNDGVTIAREIELKDPVENMGAKLIAEAAISTNDIAGDGTTTATILTHEIVNKAIEAINNGTNPVNLRIGIENAAKLVSEYLTSVSKPIKSIDEITQVGAISSGSKFIGELIAKAMDIVGPSGVISIDDAKSFDTTLDTTDGLEFKGGYSSPYMVTDSEKMLSELANPKILVSLNKINTVKEILPLLEASVESSAPLLIVASDIAEDVVTALAINKLRGTLNVVSVKCAEFGEAQKNTLEDLAISVNTILVDSAAGIEFKDLELNKLGSAEKVIISKDKTTVINGACHKDVLAKYLNNLKAKSANLTSKYDKERITKRIANLSNGVAVIHVGGATEVAQKELKLRIEDALNSTKAAVEEGIVAGGGIALMNAIEVLKQVKESNPEIALGYEIVRSSLTAPARQIIENAGQNSSKIINNIINSKQLGYGYNAETNEFVNMINNGIIDPTKVTKTALEKACSVAALLITTEVAINDELKEEKPSLNHL",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MGGISVWQLLIIAVIVVLLFGTKKLRGIGGDLGSAVKGFKKAMSDEDSAKNEKDADFEPKSLEKQQQKEAAPETKKDKEQA",
    "output": "Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MASSIICQEHCQISGQAKIDILLVGDVTVGYLADTVQKLFANIAEVTITISDTKEAAALLDDCIFNMVLLKVPSSLSAEELEAIKLIRFGKKKNTHSLFVFIIPENFKGCISGHGMDIALTEPLTMEKMSNVVKYWTTCPSNTVKTENATGPEELGLPLQRSYSEHLGYFPTDLFACSESLRNGNGLELNASLSEFEKNKKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGRKNDAASVLEATVDYVKYIREKISPAVMAQITEALQSNMRFCKKQQTPIELSLPGTVMAQRENSVMSTYSPERGLQFLTNTCWNGCSTPDAESSLDEAVRVPSSSASENAIGDPYKTHISSAALSLNSLHTVRYYSKVTPSYDATAVTNQNISIHLPSAMPPVSKLLPRHCTSGLGQTCTTHPNCLQQFWAY",
    "output": "Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTSLTLALDAMGGDHGPHVTVPAALRALKSHSSLKIILVGDKTEIDVYLRQAEQPLLSRIEVIHTDEVVSMSDRPVHALRTRKNSSMRLSIELVRDGRAAACVSAGNTGALMAMAKVLLKTLPGVDRPALVSCLPSVTQKPVYLLDLGANISCDSETLFQFAVMGSVLCEAVDKKSRPKVALLNVGTEEIKGNDQVQQAAQILQNTDQINYTGFIEGDEIYLGNVDVIVCDGFVGNITLKTSEGIAKLLVHQLKRGLTQGFFVRFLAKLIAPRIQAVLSQMNPDHYNGASLIGLRGIVVKSHGNADETAYLQAISLAVTEAQRRLPEMIKDRLESILLDINN",
    "output": "Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEIETRPHISGDEKEEEQPLSPAARLFHAPEFNCNIISVIGFKSKLDPCVFIRGFKESFIRHPRFSSKLVTDENGQNQRWVRTNVVVEDHFIVPKIKPQNIENSNAFLEDYVSDLMKIPLDTSRPLWELHLLDLKTSDAENVAVLKIHHSVGDGMSIMSLVLACMRKTSNPDELPSLPYQYRSSSRSSLLTTGSRSDSRLLWLVKVIWTAVILGLNTVCDALEFIVTTLFVKDTETPIKGDFLSTKSKQLRLVHRTVSLDDIKLTKNAMNMTINDVVLGVTQAGLSRYLARRYGEEETKNRKQKKLPKRIRLRSALLVNLRPTTGIQDLADMMEKGSKCRWGNWFGYVVFPFSIALRDDPLEHLEIAQKTISRKKNSYGAMLTYIFCRIIVKLLGIKVAASIINRMVSNTTMTFSNMVGPVEEVSFYGHPITYFASSAYGHPHALTIHCQSYMNKMTITLIVDPTVISDPHRLCDDWEESLRSIKAAVTKRESLRLWDYLRILHNRVAWLLYQIAGLLYRML",
    "output": "Bifunctional wax ester synthase/diacylglycerol acyltransferase (By similarity). Involved in cuticular wax biosynthesis (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTASPKQRIVVGLSGGVDSAVTAHLLKQQGHEVVGIFMKNWEDDDDSEYCSSNVDFVDAAAVADVIGIEIEHVNFAAEYKDRVFAEFLREYEAGRTPNPDVLCNAEIKFKAFLDHAMRVGAEKIATGHYARVRHNPATGLHELLKGLDPAKDQSYFLHRLNQSQLSRTLFPVGELRKTEVRRIAEEIGLPNAKKKDSTGICFIGERPFREFLNRYIQHAPGPILDDRGRRLGQHVGLSFYTLGQRQGLGIGGVKDKGAQRGGGEHAPWFVARKEVERNVLRVVQGHDHPWLLSHTLQATDANWVAGRPPAAGACAAKTRYRQQDAACTVTQAEGGDFALSFPEAQWAVTPGQSAVLYDGEVCLGGGVITAAGPVNSAA",
    "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIEQADEESVFRNRNLVEPDTIIDRDRIVGRDDQLRTVVSNLRKVLNENRPPNLLLYGPAGTGKSLIFDAVARQIRDISKNRGYEFGTLRINCQNLRSLDEAVYALVREAAHDLNEEIGVARHGVSTSTKYDRLYDLLDEGYDSVVFVLDEIDLLLGRRSSSSEPAYSDLIYQLSRASIESIDIQVSVAALTNDPEFMNNLDARAESSFNPRDIPFSDYDANQLQEILRNREDAFIQDALSEDVIPLTSAFAAQSHGDARKAIDLLRKAGDVANENGDLTVTENHVREAQEDVETDRSLKLVEGLTTQKKISLYATAAVAEFGKSGSTTASSRVAFPVYQFLTDVLDADGRTRETFNNYVREVGTYGQLDHERKSLGGKQGGGMYLMYEFKRDPGEIKKRLEQDERIADLSHHEDGLNRVIQAQKRNFAED",
    "output": "Involved in regulation of DNA replication."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MADEKPSNGVLVHMVKLLIKTFLDGIFDDLMENNVLNTDEIHLIGKCLKFVVSNAENLVDDITETAQIAGKIFREHLWNSKKQLSSDISSDGEREANMPGLNIRNKEFNYLHNRNGSELDLLGMRDLLENLGYSVVIKENLTAQEMETALRQFAAHPEHQSSDSTFLVFMSHSILNGICGTKHWDQEPDVLHDDTIFEIFNNRNCQSLKDKPKVIIMQACRGNGAGIVWFTTDSGKASADTHGRLLQGNICNDAVTKAHVEKDFIAFKSSTPHNVSWRHETNGSVFISQIIYYFREYSWSHHLEEIFQKVQHSFETPNILTQLPTIERLSMTRYFYLFPGN",
    "output": "Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTEAMKITLSTQPADARWGDKATYSINNDGITLHLNGKDDLGLIQRAARKIDGLGIKQVALTGEGWDTERCWAFWAGYKGPKGVRTVMWPDLDDAQRQELDNRLTIIDWVRDTINAPAEELGPEQLAQRAVDLLCSVACDSVTYRITKGEDLREQNYMGLHTVGRGSERPPVLLALDYNPTGDKDAPVYACLVGKGITFDSGGYSIKQSAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIIRYRNGKNAEVMNTDAEGRLVLADGLIDASAQHPQLIIDMATLTGAAKTALGNDYHALFSFDDTLAGRLLTSAAQENEPFWRLPLAEFHRNQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYREGWLHIDCSATYRKAPVEQWAAGATGLGVRTIANLLTA",
    "output": "Probably plays an important role in intracellular peptide degradation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MHNQYGSIFSITTWGESHGPAIGVVIDGCPAGLSLSPEDFLPAMARRRPGQLHTSPRQEPDLVTILSGVYQNKTTGTPISLLIENKDVSSSSYEQLQHCYRPGHAQFAYEGKYGFADNRGGGRASARETASRVAAGVIAKKILLSQRIETLAFLSGFGTLESKNYPKLSDSLIQQVHTSPFYTLLPQEEIQNLLLLNPDDSFGGVVSFITSPLPIGLGEPVFGKLPALLAAAMMSIPAAKGFEIGAGFSSSQMTGSAYLDAFIADESGVSLQSNRCGGALGGISIGQPLEGRVAFKPTSSIKKPCSSVLKDGTLIAYRTPNQGRHDPCVAIRAVAVVEAMLDLTLVDLLLQHRCTQL",
    "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRLETLPSEFQEALPVLEKIKAAGFEAYFVGGSVRDALLQRPIHDVDIASSSYPEETKRIFDRTVDVGIEHGTVLVLENNREYEVTTFRTEDVYVDYRRPSKVSFVRSLEEDLKRRDFTINALALDENGQLIDLFQGLDDLENRILRAVGTPAERFNEDALRIMRGFRFQATLNFDLEQDTLSAMTDCAPLLEKISVERIFIEFDKLLLAPFWRKGLEALLTSGAIEFLPDLKGSRAKLEQLFELDSDFCFSASEQAWAALLLALKTQEVQRFLRIWKTSREFAKRVADIVEIVTIRSERDLTKRDCYDYDIDLLLQAEELRQAQGLAVDFSAIHNLDASLTIHSKQEMVVNGGMLMRDFGFEPGPKLGQILKELEYAIVDGHLPNDLEAIYAYIKEKK",
    "output": "Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAVRIEVLKEDNRTRARLGKLHTPHGVIETPVFMPVGTQATVKTMTPEELKDLGAGIILSNTYHLFLRPGHELIREAGGLHAFMHWDGAILTDSGGFQVFSLGDLRKITEEGVEFRSHLDGSKKFLSPEIATQVQMALGSDIVMAFDECTPYPATRDYAKASLERTTRWLKRCQETLTTTDRQALFGIVQGSMYEDLRKQSAAEITELDLPGYAVGGLSVGEPKELMYEVLDYTVPLLPKDKPRYLMGVGSPDALIEGVMRGIDMFDCVLPTRIARNGTALTRYGKLVVRNAESAHDFSPIDPTCDCYTCKNYSRAYLRHLIKADEILGLRLMTIHNLRFLTNLMSEIRAAIKENRLPEYREKFFYEYGYLK",
    "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRESLKLSLFYFNKKERNKMNYTTQMDAAKRGIVTKEMETIAKKEGIDVKKIIECVAKGSVAIPANKNHKSLSAEGVGQGLRTKINVNLGISKDCCNVDRELEKVKKAIDMKAEAIMDLSCFGKTQEFRKRLIEMSPAMIGTVPMYDAIGFYDKELKDITAEELLDVIETHAKDGVDFMTIHAGLNREAVEIFKRNERLTNIVSRGGSLLYAWMELNNKENPFYEHFDKVLDICEKYDVTISLGDACRPGSIHDSTDASQIKELMTLGELTKRAWERNVQIIIEGPGHMSLDEIETNMKLEKKLCYNAPFYVLGPIVTDIAPGYDHITSAIGGAIAATYGADFLCYVTPAEHLRLPDLDDMKEGIIATKIAAHAADIAKGIKGAREWDNKMSVARKELDWEKMFDLAIDNEKARKYRKNSTPEVNDSCTMCGKMCAVRNMNKVMQGKDINILRNEDK",
    "output": "Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGIALILNAASDTFMLSLLKPLLDDGFGKTDRSVLLWMPLVVIGLMILRGITSYISSYCISWVSGKVVMTMRRRLFGHMMGMPVAFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMMFYYSWQLSIILVVLAPIVSIAIRVVSKRFRSISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNKMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFAILDSEQEKDEGKRVIDRATGDLEFRNVTFTYPGREVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRFYDIDEGHILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEEYSREQIEEAARMAYAMDFINKMDNGLDTIIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEQADEIVVVEDGIIVERGTHSELLAQHGVYAQLHKMQFGQ",
    "output": "Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MVKNHNPKNEMQDMLTPLDAEEAAKTKLRLDMREIPKSSIKPEHFHLMYLLEQHSPYFIDAELTELRDSFQIHYDINDNHTPFDNIKSFTKNEKLRYLLNIKNLEEVNRTRYTFVLAPDELFFTRDGLPIAKTRGLQNVVDPLPVSEAEFLTRYKALVICAFNEKQSFDALVEGNLELHKGTPFETKVIEAATLDLLTAFLDEQYQKQEQDYSQNYAYVRKVGHTVFKWVAIGMTTLSVLLIAFLAFLYFSVMKHNERIEKGYQAFVKDDYTQVLNTYDDLDGKKLDKEALYIYAKSYIQTNKQGLEKDKKENLLNNVTPNSNKDYLLYWMELGQGHLDEAINIATYLDDNDITKLALINKLNEIKNNGDLSNDKRSEETKKYNDKLQDILDKEKQVKDEKAKSEEEKAKAKDEKLKQQEENEKKQKEQAQKDKEKRQEAERKK",
    "output": "Component of the type VII secretion system (Ess). Required for the secretion of EsxA and EsxB."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIARLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLIGYGIIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPATQLVVPFFKDVMPQLGLFYILLSYFVIVGTGNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNMNFANYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR",
    "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAFDETYNEPESTEVLVKSLDPEHPAQLHYAHAGDAGADLITTVDVTLKPFERALVPTGVAIALPAGYVALVHPRSGLAAKQGVTVLNAPGTVDAGYRGEIKVPLINLDPKHTAVFHPGDRIAQLVIQRYVEARFIPAETLPGSDRAERGFGSTGVAS",
    "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATTSYRLVVAPAGSQRSSTGNVVVTTTSSGSHSSNGANGGTGGTSAGSSTLGSGLNVTTITATSGGQLQSAGNTSQSNGTTYKIEMLEEDIQSLGSDDDDEDLISSDGSLYEGDLGSMPVNDDVAHQLAAAGPVGVAAAAAIASSKKRKRPHCFETNPSVRKRQQNRLLRKLRAIIYEFTGRVGKQAVVLVATPGKPNTSYKVFGAKPLEDVLRNLKNIVMDELDNALAQQAPPPPQDDPSLFELPGLVIDGIPTPVEKMTQAQLRAFIPLMLKYSTGRGKPGWGRESTRPPWWPKELPWANVRMDARSEDDKQKISWTHALRKIVINCYKYHGREDLLPTFADDEDKVNALISQSGDEDEDMELSNPPTIHTVTTMTPPTGNSNQPQQVNVVKINSAGTVITTHTAQSNTPAPTIIQSTNNQHVTTTATLPASTKIEICQAPAQNQQHHQHHQTHLPNAVHIQPVAGGQPQTIQLTTASGTATATAVQTTAAAVSAAQAHAHSQSQAHSQSSANQTVTAQQIANAQVCIEPITLSDVDYTTQTVLSQNADGTVSLIQVDPNNPIITLPDGTTAQVQGVATLHQGEGGATIQTVQSLTDVNGHENMTVDLTETQDGQIYITTEDGQGYPVSVSNVISVPVSMYQSVMANVQQIQTNSDGTVCLAPMQVENGDQLETITMSPGMHQMMIQGGPGQEPQLVQVVSLKDATLLSKAMEAINSGNVKSEDTIIMEQ",
    "output": "May function as a positive regulator of transcription in developing and differentiated neurons, regulating common aspects of neuronal differentiation and maintenance. Requirement in the CNS may be higher than in the peripheral system. Vital for development of the indirect flight muscles."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTLENRSTCLMTCQSSLLPKKPRFLSQKMWAPHLVVAYLIFVTLALALPGTQTRFSQEPADQTVVAGHRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIQPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQTVLEGERVIFTCQATANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPVGIIAGATIGAGILLVFSFAALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTTSISTATRVMKAIYSSFKDDVDLKQDLHCDTIETREEYEMKDPTNGYYNVRAHEDRPSSRAVLYADYRAPGPTRFDGRPSSRLSHSSGYAQLNTYSRAPASDYGTEPTPSGPSAPGGTDTTSQLSYENYEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTPYEAYDPIGKYATATRFSYTSQHSDYGQRFQQRMQTHV",
    "output": "Required for proper function of the glomerular filtration barrier. It is involved in the maintenance of a stable podocyte architecture with interdigitating foot processes connected by specialized cell-cell junctions, known as the slit diaphragm (By similarity). It is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLKMESTQQMVSSIINTSFEAAVVAATSTLELMGIQYDYNEVFTRVKSKFDYVMDDSGVKNNLLGKAITIAQALNGKFGSAIRNRNWMSDSKTVAKLDEDVNKLRMTLSSKGIDQKMRVLNACFSVKRIPGKSSSIIKCTRLMKDKIERGEVEVDDSYVDEKMEIDTIDWKSRYDQLEKRFESLKQRVNEKYNTWVQKAKKVNENMYSLQNVISQQQNQIADLQQYCNKLEADLQGKFSSLVSSVEWYLRSMELPDDVKTDIEQQLNSIDLINPINAIDDIESLIRNLIQDYDRTFLMLKGLLKQCNYEYAYE",
    "output": "Plays an important role in stimulating the translation of viral mRNAs. These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding. The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKIGIIGATGYGGAEIMRIMRTHPYADECILYSSSDEGARYDAAYPHLVKLTDQHLQPIEVKRIANEIDFLFMAAPPGISSRLTPQFDAYDIPIIDLSGDLRIQNPSVYEKWYKREAAPEHVLQKAVYGLSELNREDIKTAQYIANPGCFPTAVLLGLAPLVKSGSINESFVIIDAKTGVSGAGRKPSMGTHFSEVNDNFKIYKVNEHQHTPEIEQTVKQWNSAFKPITFSTHLVPMTRGIMATIYTELKDSMDAEQLQLIFSKFYKDSYFVRVRETGSFPATKEVYGSNFCDIGVTVDERTNRVTIVSVIDNLMKGAAGQAVQNFNIMNGLSETAGLEFTPIYP",
    "output": "Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTDEKVINKKLVGDNKLFRHQAKFVAGAMDIKQLPNFALPQIAFVGKSNVGKSSLINTICNNKKLAKVSNTPGRTRQINFFNLVDKLIIVDLPGYGFAQVPNQVKDQWEILINHYLRKSDNLKLVNLLIDSRRGIKENDKKVAELLLANKRDFQIIFTKSDKVTDRKNLNLEAQNFLATLNYSCNLIYVSSRSKEGARELKTSLAKCIKLEK",
    "output": "Necessary for normal cell division and for the maintenance of normal septation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MLNSFKLSLQYILPKLWLTRLAGWGARKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNDFFVRPLRDDVRPVNTDPNVLVMPADGVISQSGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGSFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGVIKRWTWPEGESEGSVALLKGQEMGRFKLGSTVINLFAPGKVTLAEQLQSLSVTKIGQPLAVSTELFVTPEAEPAPLPEEEINAEHDASPLVDDKKDES",
    "output": "Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQQVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAGVLTRAEAAEINLRSDILNAVGITLDETTTRENVMQLFNVLLGDNHGLDIDTLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ",
    "output": "The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTERLEALGARVSIGHDAANIEGANAVVVSTAVRSDNPEVLAARRLRVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLTSAGANARLGTGDFIVAEADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCIDDANVRQIVPLISKPVVRYGFAADAQVRAENVEARDGRMHFTVRREGREPLPVVLNLPGLHNVQNALAAIAIATDLDVADAAIQQALAEFNGVGRRFQRYGEIAAAGGGAYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAPISTANGDALSRALRAAGKVEPVFVATVDEVPDALAKLARDGDVVITMGAGSIGGVPGKLAQDTQQKG",
    "output": "Cell wall formation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSTYSKKTSYTVKSSSSGSIPRNFSSLSYSGPSMSRQSYSARSSYGGVNRGMGAGMGGGSGFISSSSAYGLGMGMGTGMGAGVVAPIQAVTVNKSLLAPLNLEIDPNIQIVRTQEKEQIKTLNNRFASFIDKVRFLEQQNKMLETKWSLLQNQTATRSNIDAMFEAYIANLRRQLDSLGNDKMKLEADLHNMQGLVEDFKNKYEDEINKRTECENEFVLIKKDVDEAYMNKVELEAKLESLTDEINFLRQIFEEEIRELQSQIKDTSVVVEMDNSRNLDMDAIVAEVRAQYEDIANRSRAEAEMWYKSKYEEMQTSANKYGDDLRSTKTEIADLNRMIQRLQSEIDAVKGQRANLENQIAEAEERGEMAVRDAKGRIKDLEDALQRAKQDMARQIREYQDLMNVKLALDIEIATYRKLLEGEEDRLATGIKAINISKQSTSYGGYPMESAGSSYSTYSSGYSSGLSGGYGGGYSGGYSGGYSSGSGYSDTVSQTKKSVVIKMIETKDGRVVSESSEVVQD",
    "output": "Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MICPDCGKGIEATFKFCPYCGKPLPAEKHEGSQSFVKPFTSSSQGSRRKTNTSSETSSKKVKWCSYAASPSLPLPSEGKSSGSEDTLSTSGKPKGHLSRSPTPRSSPQTTRQSPQTLKRSRMTASLEALPVGTVLTDKSGQHWKLRCLQTRDDQGILYEAESDSTTGSESSPQKQRFSLKLDAKDGRLFNEQNFFQRAAKPLQVNKWKKLYSIPQLAIPTCIGFGVHQDKYRFLVFPTLGRSLQSILDDFPKHVMSVRSVFQMACRLLDALEFLHENEYVHGNVTAENIFVNPENLCQVTLAGYGFTFRYSPGGRHVAYTEGSRSPHEGHLEFISMDLHKGCGPSRRSDLQTLGYCLLKWLYGTLPWTNCLPNTEEIVKLKQKFLDNPEGLVGQCSRWITPSETLQEYLKVVMALQYEEKPPYSTLRNELEALLQDLRASAYDPLDLQVVP",
    "output": "Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in the nucleus."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTRPSLVRCYSLFFTALIVMAIICPAWSEEIPKSRKKRAIPIAYVGMAVAPQVFRWLVRAYGAAAVTAAGVTLRRVINRSRSNDNHSCYGNRGWCRSSCRSYEREYRGGNLGVCGSYKCCVT",
    "output": "Significantly inhibits the growth of Gram-negative and Gram-positive bacteria and fungi in vitro."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MANLKAIRDRIQSVKNTKKITEAMRLVAAARVRRAQEQVLATRPFADRLAQVLYGLQSRLRFEEANLPLLRKREVKSVGLLVISGDRGLCGGYNNNVIRRAENRAKEIKAEGLNYQFVLVGRKSTQYFQRRDQPIDATYSGLEQIPTAAEANQIADQLLSLFLSEEVDRIELIYTRFLSLVSSRPVVQTLLPLDPQGLEAADDEIFRLTTRGGKFEVEREKVASQVRPLAPDMIFEQDPVQILDSLLPLYLSNQLLRALQESAASELAARMTAMSNASENAGELINTLTLSYNKARQAAITQELLEVVGGAEALT",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSRKYFGTDGVRGKVGTFPITPDFAMRLGWAAGTVLASTGTKEVLIGKDTRISGYMLESAMEAGFSAAGVNVALIGPMPTPAVAYLASTFRADAGVVISASHNPFYDNGIKFFSNTGTKLNDAQELEIEALLEQALEHNALQCVASEKLGKVRRIDDAAGRYIEFCKGTFPNHLSLAGLKIVVDSAHGAAYHIAPNVYRELGAEVISINDKPNGVNINDHCGATHLDSLQSAVMIHEADLGIALDGDADRVMFVDHNGHVVDGDEILFILAQAAYQKGEMQGGVVGTLMSNLGLELALKGMDIPFVRAKVGDRYVVEQLKETGWQLGGEGSGHILSLKHASTGDGIVASLQVLKAVLESGKRLAELKAEMTKLPQVLINVRLTSGCADSILSKDSVKQAVIAAEEVLGNQGRVLLRKSGTEPLIRVMVESTDISLTQQQAEYIAQAVKVA",
    "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MWLGLRLFHRPFSSLAARGLVYEKHGEPLQVLRLKNVNITHPADNEVRVKMLAAPINPSDINMVQGTYALLPQLPAVGGNEGVGVVVEIGRHVSSMRPGDWVVPVDAGLGTWCTEAVFSEDSLVRVPSDIPVAGAATVSVNPCTAYRLLSDFETLRPGDTIIQNASNSGVGQAVIQIATSLGITTINVVRDREDLSSLIQRLRDLGADHVITEEQLRKPEMKDLFKNCPRPRLALNCVGGKSTTEMLRHLDYGGTMVTYGGMSKQPVTVPVSALIFKNVKLCGFWVTQWKKERAQTDREEIVKMIRDLCDLIRRGKLVPPPSTQRPLEDFSRALQDSQTPFLSRKQILIM",
    "output": "Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro (By similarity). Functions in pronephros development, regulating late differentiation of all pronephric tubule segments ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDEPPIVLPTEEDGPFSNCVSIAFVNDKSIPVELRIRKAIRGKVTFTQELVVAARRLYLDGELERPDLNYHVAADFYDPFMIPVPDHRNWEYNPLYPREWPRLIDRDLVQKIKMSNTYKKNQARRKRRRLLRIFHRKRGGEFLNYLWHSKENDVHYKRYMAAYQFPLPFEKCIRDVVREELKDPETSFSKPPSVVHHSKIRPATPDLLKLAKYLGKDRFCFIVTPFKFRSQFRLRYYKKSPFKRSNILEKWLKFKKVRDQGVFNIRDAAREVKKLLQRKNVYHMTDPQCEQEFWDVYRLQMQWLEEDNIEENITMLRENLSKVTDEEFNRSVYIMRPENRASIHDDVTFTTDAEINLKPIVLELFRNNMPLEDIRQVKECIDDMINLTVCQELIPQVATIETVRDYSGVEQHRLKYIRPENELEIMFQLATVLVKNENTHDQEITSPMFALLRTEQYLWSIPLRPFLRMYTDWRKTKLNFKKFRKFSPELVSKAPIDLFKVFLTTNMDKKGVATKDTDCFDYRTASEIKKLYHEEFIRVRPIIEHQRFHRCYTSVITEEPLPNPFYWVHRGQWEKVYECNWKQRVKPLAGRFSWKTKHPNICDLPRLEKDDKQEMEMLAKMREKIREYNKEKEKHPFYVSSSLPEFASTSDFVKFPISNTGIKYTAPRRNQPKVQRSLVTYTRFRLAELEDKDFSFPEEKMLEKNRLLEKLNFEERLQLDALMSKDVKYKPRMIPEKGFLQLQDEKLILKRLCEKEDEWSGKQKRRFPDLYEQATQEAERLGDPDASTSGTSNKELGLLPVWKHDDFRDLKKINVLGSKEYPISSPYLIKRLHYDIHLEIVRDKLKSWIYRTELWEKMKPVYERLKRDKEKREKEWHEMRAAQRAQKEKEEEDQRRMDMGIEHGQESLLKSITPEVEQQILLPISRENSFEEMLPAPQEAYDEDLDQDIDIHFDGAESVCTGIRLDSEDRELVDSPDQVENEEPERVEAVTENIRQEMSDAEMRDLMRKKREQYSMLFPNVPQPFQPLNRFDVTAPGAGIVPPYDEAPDFDLSAYLEEDHVRIPTLSTVEINSLLKDQDLVEEQEIVEEEETPLVVEEPDIPAAPVLSAEEKASRISREMSALRKLPDAAFNYASDRDGVVVEEVETIEEIQEIYNDKLEKMIAARLGSIAQGANIERLSEDQLLGDQGSEDISFEEIQVDLLLESGVEVQVNQSVTISRSSTSFESLLVEDPEEHPEQLPVSASEKANNQIVPEVEVEGSVVPVTNQQEENVTSEGPTLQEGSSIPSSSHIYTVDELLGTESPGPEATETPVAEESPKKKSGKTTRGRPKKVKENLKKRIQPRRGQKEEAAHEPEVVEEQEQVEPEVGPEVVHEPVPAPAAQLETEPIEQQIEEPDKVFEPIIEALPLFETSPVPAPEGNIPSRAHSSDDDVQVISSETDPNGPINLVEQVQNDKLTAYQYSTEELLGEYGELDEAGAPSPSEIVVHDEVLQDEVLQPNPKSSKKRGRRRKKTPPHIAKARKVFTSISKTEEIELAPTPTQQSRKRMANVSSEEATATRRQKRAKVEEPNDSDVSRVLTPEPEDLHETERPGHVGEEGFETPSLRTGRESTASSVKTSRSKRLFLSKNNPVPRMRIQSQAGTNASPTPARRTGVARDSVSPDGASEKLKQLPKSVQDIFEVFDVERSAERGESATVTNLEGPVKIEIEDENWMAPPAITETSRKSKKRLRAEKQQQILDDIKLELNGEPPQKRECEILMERVQVKIEEGVENADCRIVQANFNCKSVEEHETLPLKIIRVFEENEKPVHKFFMTQIIWKEINEAFMTDPEKFMLLVRILFSDRNISGQIYKISMTVTDRIKGFDDDFIKLLTQFPKKLSQEHKPLVDYNKLAHALREKASLHLNNHKITPFTFHGVISNITEMKEKIIGRCEIGMLTDGDRDVLNSTENMLLGAYMKSVLRMTAQSQVSWAHPEYIKRRLEMIYYGWRMFLGSGGFFRVALAINRKDVKPMSQQFRDFFIEYLKDVNENYAKAVELVQMDEDKLMEAMIEKAGLSSIDLLALDEDVQGQVSESHKHKCVQCSIRNQSVYFSSYSLLELHGKLHQNLHELAPEDADDCQDCYETLTSSFEVIVHRINHHHSRRCFFADD",
    "output": "Component of the SDC complex that functions in sex determination and in X chromosome dosage compensation specifically in hermaphrodite (XX) animals . Plays a central role in the recruitment of the condensin I-like dosage compensation complex to the male sex-determining autosomal gene her-1, thereby contributing to its repression and initiating hermaphrodite sexual development . Involved in the recruitment and assembly of the dosage compensation complex and the dosage compensation protein dpy-21 onto the X chromosomes in hermaphrodites, which leads to a reduction of X-linked gene transcription and an equalization of X-linked gene expression between the sexes ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "RTCESQSHKFKGPCFSDSNCATVCRTENFPRGQCNQHHVERKCYCERSC",
    "output": "Plant defense peptide."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREKGMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAEGKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHLGAYQHNGGRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNESRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFESEVAATMAAALNN",
    "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSWWQVISLAVVQGLTEFLPVSSSGHLAVVSRVFFSDDAGASFTAVTQLGTEAAVLVYFARDIVRILRAWFDGLVVKSHRNADYRLGWYVIIGTIPICVLGLLFKDEIRSGVRNLWVVATALVVFSGVIALAEYLGRQSRHVEQLTWRDGLVVGVAQTLALVPGVSRSGSTISAGLFLGLDRELAARFGFLLAIPAVFASGLFSLPDAFHPVTEGMSATGPQLLVATLIAFVVGLAAVSWFLRFLLRHSMYWFVGYRVVVGVVVLILLATGTVAAT",
    "output": "Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQIFLVLALCGLAAAVPSEDRKLSDKATTLADRSTTLAFNLYHAMAKDKNMENILLSPVVVASSLGLVSLGGKATTASQAKAVLSADKLNDDYVHSGLSELLNEVSNSTARNVTWKIGNRLYGPASINFADDFVKNSKKHYNYEHSKINFRDKRSALKSINEWAAQTTDGKLPEVTKDVEKTDGALIVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVPMMHRTGLYNYYDDEAEKLQVVEMPLAHKLSSMIFIMPNHVEPLERVEKLLNREQLKTWASKMKKRSVAISLPKVVLEVSHDLQKHLADLGLTEAIDKTKADLSKISGKKDLYLSNVFHAAALEWDTDGNPYDADIYGREEMRNPKLFYADHPFIFMIKDSKTNSILFIGRLVRPKGDKMRDEL",
    "output": "Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRSLQAPVVCPSVRPRQLGVSALLVNCSVSKTRSLRKQFWGNQTKNDKSQAATVNLRLHLRRYKSIKCLFSSHSDGTGSTAENFNENDEDYVKSSVLEAVEVKSGPDGFMVKMKDGRQLRCVHNNPQGGNLPNYAPHSAIVLKMEDGTGLLLPIIVLEMPSVLLMAAMTNVQIARPTMYQVVKDMVDKMGYEVRLVRVTTRVHEAYFAELYLSKVGDKSDCVSFDLRPSDAINIAVRCKVPIQVNKYLAYSDGMRVIDSGKLSKQTPASDGLLFTELDRPNGQPCFDTKEFDLVRNMMQAVDEERYDEAAEWRDKLGKFQAKRKLRKYT",
    "output": "Bifunctional nuclease with both RNase and DNase activities. Involved in basal defense response. Participates in abscisic acid-derived callose deposition following infection by a necrotrophic pathogen (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MPIEFIATSKLPTAFGEFNISVFQDPVTGEEHVALSKGLENPPTDPVLVRVHSECLTGDAFASLKCDCGPQLQATQKLINEAGQGVILYLRQEGRGIGLTNKIRAYALQDQGHDTVDANLLLNLPADARRYDMCSIMLDHLKVKEVKLITNNPLKIQALKDQGINVVDRVPLTVGRNPFNEQYLKTKRERMAHLYQKDDF",
    "output": "Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKIKVRYAPSPTGFLHIGNARTALFNYLFAKHNQGEFIIRIEDTDFSRNVKGGEASQLKNLRWLGIDWSEGPDIQGPFGPYRQSERLAIYQKYAQKLLDQGLAYKEFQENTTTFAIRFRVPTNQTFSFDDLIRGKLTFQSQEIEDWVIIKSNGYPSYNFAVVIDDHLMQISHIFRGEEHITNTPKQIMIYQTFQWHLPQFAHMTLILNDNKKKLSKRDANIMQFIEQYEKLGYLPQALFNFLSLLGFSPLSQTEILSPQELINLFDVARLNKAPAMFDTVKLDYLNNQHLRKLTPEVIASFIVQKKYLTLTTAPTNDKEWMTKFVSLFQDRMNYIQQIADFYQLFFQTKPSLSQEATIFLQTNPQTTLILKTFYNVFDVIVFKKDVIFNAIKQVANQNDFSKKTLFMALRIGTTCKMHGPSIALLLELLGKKQVLKNLSYVLKQAQKF",
    "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTVSFRPTADLVDDIGPDVRSCDLQFRQLGGRTEFAGPISTVRCFQDNALLKSVLSEPGGGGVLVVDGGGSLHTALVGDVIAELARANGWAGLIVNGAVRDSAALRGMDIGVKALGTNPRKSTKTGAGERDVDITLGGVTFTPGDIAYSDDDGIVVAVGD",
    "output": "Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTCGFSRADRSPYHGPVTSTVARDVSGVRTYQVRTYGCQMNVHDSERLAGLLEAAGYRRAAEGAEVADVVVFNTCAVRENADNKLYGNLSHLAPRKRSNPQMQIAVGGCLAQKDREAVLRRAPWVDVVFGTHNIGSLPTLLERARHNKAAQVEIAEALQQFPSSLPSARESAYAAWVSISVGCNNSCTFCIVPSLRGKEVDRSPDDILAEVRSLVADGVLEVTLLGQNVNAYGVSFADPALPRDRGAFARLLRACGEIDGLERVRFTSPHPAEFTDDVIEAMAQTPNVCPALHMPLQSGSDRVLRAMRRSYRAERYLGIIDRVRAAMPHAAITTDLIVGFPGETEEDFAATLDVVRRARFAAAFTFQYSKRPGTPAAELDGQIPKAVVQERYERLVELQESISLQGNQALVGQTVELLVATGEGRKDSATARMSGRARDGRLVHFAADDRVRPGDLVTTVITGAAPHHLIADAGILSHRRTRAGDAHAPAGARAASVSACPPSGRRRPGPTRWMCLMNDDRNHDDPRLGALRTEIEAAERRVAGGIDPGARGFVVSILVFVLLGSFILPHTGDVRGWDVLFGTHDAGAAAVALPSRVFGWLALVFGVGFSTLALVTRRWALAWIALAGTAIAGAAGMLAIWSRQTVPAGHPGPGWGLIVAWITVLVLIYQWARVVWSRTIVQLAAEEQRRRVAAQQQSTTLLDDLPKPEDPAAGT",
    "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSLLEQVSVSKKANIYFDGKVASRSVFLADGSKQTLGVVLPGEYEFSTSQGEVMEVTSGRFEVLLPESTVWQEFSEGTQFELAANVSFKIRNTAIAEYCCSYL",
    "output": "Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "DECFSPGTFCGIKPGLCCSARCLSFFCISLEF",
    "output": "Delta-conotoxins bind to site 6 of voltage-gated sodium channels (Nav) and inhibit the inactivation process. This toxin acts on Nav1.2/SCN2A, Nav1.4/SCN4A, Nav1.5/SCN5A (weak activity), Nav1.6/SCN8A (EC(50)=2.5 uM)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDSSTPQNYLAVIKVVGIGGGGVNAVNRMIEEGLRGVEFIAINTDAQALLMSDADVKLDVGRELTRGLGAGANPDVGRQAAEDHEEEIQEVLKGADMVFVTAGEGGGTGTGGAPVVARIARSLGALTIGVVTRPFTFEGRRRSNQAENGIETLRDEVDTLIVIPNDRLLSISDRNVSMLDAFKSADQVLLSGVSGITDLITTPGLINLDFADVKSVMQGAGSALMGIGSAQGEDRAVKAAELAIASPLLEASIDGAHGVLLSIQGGSDLGLFEINEAARLVQEVAHPEANIIFGAVIDDALGDQARVTVIAAGFDSVSQETNANNSSPAQRQAESTRAAFGGDASRPSGLGRSPQRGGNSYGAPAAGFGSRQGQGQDDDIPDDAGFDVDLPAEADAPSSSNTSARKDSLDFPDFLK",
    "output": "Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIDRYKHQQLRIGSVSPQQISAWAKKILPNGEMVGEVTKPYTFHYKTNKPEKDGLFCERIFGPIKSGICACGNYRVIGDKKEDPKFCEQCGVEFVDSRVRRYQMGYIKLACPVTHVWYLKRLPSYIANLLDKPLKELEGLVYCDFLFARPVAKKPTFLRLRGSFEYEIQSWKYSIPLFFTTQGFDTFRNREISTGAGAIREQLADLDLRLITDSSLVEWKELGEEGATGNEWEDRKIGRRKDFLVRRMELAKHFIRTNVEPERMVLCLLPVLPPELRPIIQIDGGKPMSSDINELYRRVIYRNNTLTDLLTTSRSTPGELVMCQEKLVQEAVDTLLDNGIRGQPMRDSHNKVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPREIAIELFQTFVIRGLIRQHAASNIGVAKSKIREKEPIVWEILQEVMQGHPVLLNRAPTLHRLGIQAFQPILVEGRAIFLHPLVCKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHMNLLSPAIGDPISVPTQDMLMGLYVLTTGNHRGICANRYNPSNHRNYQNEKIDDNNYKYTKEPYFCSSYDALGAYRQKRIYLDSPLWLRWRLDQRVIASREVPIEVQYESLGTYHEIYGHYLIVRNVKKEILCIDIRTTVGHISFYREIEEAIQGFCRACSYGT",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDFELKLLPLARICSEKCDALLVLIPQDLSAGGDDPLSALAALALKAGDLEAKPGKLLSAYRTPGIAATRVVLAGVGDASPRNVRTAVNAAMANLKNGNTQRVVVSLAAMNNAQPEIVRAAVVACSEAAYVYSTTKSKVSPVKLQRVVIGVNELSVARPGFDKALALVKGIEFAKEWANRPANHATPTLLAGAARELARLRNIKVEVLGPKEVAKLGMGSFMAVAQGTSEPLRFIVLRYEGAAKSVAPVVLIGKGITFDTGGISIKPAAEMDEMKFDMCGAASVLGTFRALAELQPALNVVGLIPASENMPGGRALKPGDVVTSMSGQTIEILNTDAEGRLVLCDALTYAERFKPRAVVDIATLTGACVIALGGVRSGLFSNNDELAQSLAAAGESSLDPCWRMPLDDDYAEGLKTNFADVANVAGRAGGAVTAAKFLHRFAGSFPWAHLDIAGTAWKGGAAKGATGRPVPLLLDYLLGQVTAAAPRKAQPKARSAKRSKPVSRTRA",
    "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRNSNRGPAFLILFATLMAAAGDGVSIVAFPWLVLQREGSAGQASIVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSGAAVAGVPLVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGWSLDRINGAYEAILNLAFIVGPAIGGLMIATVGGITTMWITATAFGLSILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLRFVWNLRVLRTLGMIDLTVTALYLPMESVLFPKYFTDHQQPVQLGWALMAIAGGGLVGALGYAVLAIRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLVYGPIQPIYNYVIQTRAAQHLRGRVVGVMTSLAYAAGPLGLLLAGPLTDAAGLHATFLALALPIVCTGLVAIRLPALRELDLAPQADIDRPVGSAQ",
    "output": "Efflux pump that contributes to intrinsic antibiotic resistance. The pump uses the electrochemical gradient as a source of energy. Confers resistance to various antibiotics, including tetracycline, acriflavine, spectinomycin and p-aminosalicylate. May be involved in export of toxic by-products that accumulate during stationary phase when nutrients are limited."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSSKVGGGKGGKSKTSSEAKVLTTRSSKAGLQFPVGRIHRFLRNKNANNVRIGAKAAVYVASIMEYLTAEVLELAGNAAKDLRVKRITPRHLQLAIRGDEELDLLIRATIAGGGVLPHIHKSLVAKNAPLKKPKALDA",
    "output": "Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received. Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins. Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes. Involved in chromosome stability (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTTNDAGRIPSAAGGAELAALYRLLTWLSPAFPIGGFSYSSGLEWAVEAGDICDAAALRGWLATMLTDGSGFCDAAFLVHAHRATELDDIKRLSEVAELAAAFVPSRERQLETAAQGRAFIEIARSAWSCAGLDEAVAQCDVVVYPVAVGMVGALHGVPLEPLLHGFLHALVSNWISAGSRLVPLGQTDSQRVLAALEPVVVATADRSLHASLDDIGSATFRADLASLRHETQYTRLFRS",
    "output": "Required for maturation of urease via the functional incorporation of the urease nickel metallocenter."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAKEKFEEAMAKLEALVRKMETGDMTLEESLKAFEEGIRLSRLCASRLDDAERRVEMLIAENSNVTVQPLRENGEKNES",
    "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSKVHNSEYIKELVVDNTSYKIYDINKAASDIGLPLKKLPYSLRVLLENVLRTNGNKENLLVFKEWLKTKKSNTEIDFMPARVLMQDFTGVPAIVDLAAMRDAMQKIGCNPLKINPLIPVDLVIDHSVSVDSYGNKESFDQNVHMEMKRNIERYQFLKWGQQAFNNFKVVPPGTGICHQVNLEFLSQVVWHNDGTAYPDSLVGTDSHTTMVNGLSVLGWGVGGIEAESAMLGQPITMIIPEVIGVKLIGKLAGMATATDLVLTITEILRRKKVVGKFVEFFGNGLRNLTISDRATISNMSPEYGATCGFFPIDQETLKYLEVTGREITQIKLVEKYAIEQNLWYNCEDTQEYTEVLELDLSTVYSSLAGPKRPQDRVNLNCVASNFQNELPYFALANKDIDKKYAVANQNYAIGNGDVVIAAITSCTNTSNPSVMIGAALLAKKALEHGLNVKPWVKTSLAPGSKVVTEYLKLSGLDKYLDALGFNLVGYGCTTCIGNSGSLNPEIENTINKNRLVVASVLSGNRNFEGRINPLTKASYLASPILVVAYALSGTLNIDLTNTPIGANIYLKDIWPSQKEIDEVIANSINSSMFIEKYADVFNGTKEWRDLQITTGTNYNWDKNSTYINNPPYFDNIGSEHSIKDIKSARILAIFGDSITTDHISPAGSISKNSPAAKYLIKHHIEPLDFNSYGSRRGNHEVMMRGTFANIRIKNEMCNGVEGGFTINQLSGVQQTIYDTAMDYKAHDIPLVIFAGKEYGSGSSRDWAAKGPGLLGIKAVIAESFERIHRSNLVGMGILPLTFTGKNTRLNLKLDGSEIIDLIGLSENIKPYNLVKCVIKKQTNEISTIDLILQIFTENEINYIKHGSIMQFVVESLKG",
    "output": "Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFEGEEA",
    "output": "RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRVYNCHFCSSPVYPGKGIMFVRNDSKEFRFCRSKCHKNFKMKRNPRKLRWTKAFRKAAGKEMVVDSTLAFSARRDVPVRYNRDLVEKTLEAMEKVEEIRLKRERAFYKNRMRGNKAAQLEEDRKLVEAHPELLREREVELRRMQEAGEDDDDEDMSEMEVSEEEESEEEREKVEIALKSKSKRKMRA",
    "output": "Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of YALI0_B00990g/NOG1 to pre-60S particles. Activates and recruits ATPase AFG2 to cytoplasmic pre-60S ribosomal particles."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSQFSFTKMHGLGNSYIYVNMFEEQIPEEDLALVAEKVSNINTGIGADGMILICPSDVAPVKMRMFNNDGSEGKSCGNGLRCVAKYAYEHKLVEDTVFTIETLAGIVTAEVTVEEGKVTLAKIDMGAPRLTRAEIPMLGEGETPFIRENFLYNNHRYAFTAVSMGNPHAVIFVDDVEQAPLTTLGPVLETHEMFPERVNVEFIEILNEEEMNFRVWERGSGVTQACGTGACAAVVASILNGKMERGKEITVHLAGGDLMIAWTEEGNVLMKGPAEVICHGVYEYKIEA",
    "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKSTFGLLALAAAAKLVSAHATVHAVWINDVDQGAGNSADGYIRTPPNNSPITDVTSADMTCNVNGKNSVAKTLSVKAGDKVTFEWHHDSRSASDDIIASSHMGPVMVYMAPTEKGTAGNGWVKIAEEGYSNGKWAVANLIANKGKHSITVPDVPAGEYLLRPEIIALHEGNRQGGAQFYMECVQVKVTSAGTKTLPAGVSIPGAYKATDPGVLFDMYNSFTSYPIPGPAVWDGSSSGSSGSSDSSPATTAPEASVTSAPTKQGSADTSASPTTFVTATKPTTTAAPAAPPASTGSNSGSGSSGSGSASGSVKIYQQCGGKNYSGATSCEAGLTCKEWNPYYHQCLKA",
    "output": "Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVPEPGPSANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPPRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATRDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN",
    "output": "This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKSITINGSKRESVGKKATKALRNAGQVPCVLYGVEGDPLHFAAEEISFKNLVYTPDVHTVKIKLKSGESYDAILQDIQFHPLTDAILHIDFYQIFGEKPITMEIPIHTEGVARGVKNGGVLRYNLRRLKVRGLPADLPDYIVANVSKLKIGQKLYVTGVDSKDFVIQHPDNTVICQVRTSRNLVELEDEDEDEDEVAADEVPATEVDDQAAVKEGEGKE",
    "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATAALRQIWIPRFLPVPWFLCGSRRYASSSFKAADLQLEMTQEPHKKPDPSQPLLFGKTFTDHMLMVEWNQEKGWGQPRIQPFQNLTLHPACSALHYSLQLFEGMKAFKGGDQRVRLFRPWLNMERMLRSALRLCLPSFDKIELLECIRRLVEVDQDWVPGSMGTSLYVRPVLIGNEPSLGVGHPTRALLFVILSPVGAYFPGDALKPVSLLADPSFIRAWVGGVGNYKLGGNYGPTVLVQQEAQKKGCEQVLWLYGPDHELTEVGTMNIFVFWTYEDGVLELVTPPLDGIILPGIVRQSLLDLARTWGEFRVVERKITMKEFLRALKDGRVREVFGSGTACQVCPVHQILYQGKHFHIPTMENGPQLILRFHKELKAIQYGSKAHEWMLPV",
    "output": "Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine (By similarity). May also function as a transporter of branched chain alpha-keto acids (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKFLLLNGPNLNLLGTREPQIYGSQTLAQICDTLREQAKAHGHVLEDFQSNAEHELVERVHRASREGIDFILINPGAFTHTSIALRDALLGVAIPFIEVHLSNVHAREPFRHKSYLSDVARGVIMGLGPKGYALALDAAIHLTQKN",
    "output": "Catalyzes a trans-dehydration via an enolate intermediate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKSWSVNKIIMLISLFLLEVIDSQIISNNIINNFNTKQNSNNIKMTYGRFLEYLDMGWIKKVDFYDNGRIAIIEASSPELGDRLQKIRVEIPVGDSPLIVKLRTAKVDFTAHSTINSKGIFTQLSNIFIPLIIIIGLIFLFRRSTNFMSGPGQLMSFRKARAKVQTEINTDVVFDDVAGIDEVKEEFEEVVTFLRKPQRFLSVGAKIPKGVILIGPPGTGKTLLAKAIAGEAGVPFISISGSEFVEMFVGIGASRVRDLFKTAQQNAPCIVFIDEIDAVGRQRGAGIGGGNDEREQTLNQILTEMDGFKENTGIIVIAATNRVDVLDGALLRPGRFDRQVSINLPDIKGRLEILKVHAKNKKLDSNISLGLIAQRTPGFSGADLANLLNESAILTARRNKFAITMSEVNTAIDRLLAGLEGTSLTDTKNKRLIAYHEIGHAVIGTLLKYHDEVQKVTLIPRGQARGLTWFIPNDEQALISRGQLVARIIGTLGGRAAEEVVFGSSEITTGASNDLQQITNLTRQMVTRLGMSTVGPISLDANVEQVFIGRGIKNNNEFSASVANKIDDQVKIIIKHCYDQAVNIIKQNRFLIDQLVNTLIQEETISGNDFREQINNYTKLPKKLSTLSEKNNVNPKITESFVVF",
    "output": "Acts as a processive, ATP-dependent zinc metallopeptidase."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTLGPLMIDLKGVTLDSEERAWLGHSWVGGVILFSRNYESPEQIAALIKAVHALKEPRLLVAVDHEGGRVQRFRDGFTLLPPASLLGKLYDRDQRQAQRLAMITGWLMAVELRAVGVDFSFSPVLDLDRGVSAVIGDRAFHGEPDAVIALARAYIRGMAWAGMAAVGKHFPGHGSVVADSHTALPVDKRSWRQIREGDLLPFEHLARAGLPAVMPAHVRYASVDSRPVGFSPFWLETVLRGQLGFQGAIISDDLSMAGAAEVGDMSARMQAALSAGCDMALVCNDPDGYALLLDELKGDPYPQTSPRLLRLYGRYPLTRSQLYHNPAWQRAVQMLAAYGEF",
    "output": "Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKQQKKEVEQRRCFGIISHPDAGKTTLTEKFLLFGGAIQLAGAVKARKAARHATSDWMSIERDRGISVTTSVMTFSYRDFFINLLDTPGHQDFSEDTYRVLTAVDSALMVIDSAKGVEAQTEKLMEVCRMRNTPIITFINKMDRDGMAPLDLLSDIEEKLQIECAPLTWPIGAGKGFAGVYNLYKKELQLFTAGGKTRQKDGIVIQDLDDPKLAELIGESKAEELREDIELLEGAANPFEMEHYLSGSQTPVFFGSAINNFGITELLDALVEMAPAPGLRPAESRDVSPLEEDFSGFTFKIQANMDPAHRDRIAFVRICSGKFNRGMKVMHHRIGKEMIISNATMFMAQDRANVEEAWPGDIIGVHNHGTIKIGDTFTIKEPLKFTGIPNFAPEHFRRVMLKDPMKAKQLNKGLTQLAEEGAVQVFRPLTSADNILGAVGVLQFDVTMARLKAEYNVDCIYEAIDYNTARWVECPDNKMLDEFRKANQANLALDGEGQLAYLAPSQWRLGFVQENWPDVVFHKTREYN",
    "output": "Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "METIARHSQARSSAQKLRLVADLIRGKNIEHALNILTFCNKKASILVKKVLKSAISNAEHNHGSDINNLQVKKILIDEGPTMKRMMPRAKGRSDRILKRTSHITIVVSDSKVKDKKGRG",
    "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTAHKPFSAVILAAGKGTRMRSDTHKILHALAGRPLLGWVLDSLAPLSPDHTVVVTGSGREQVENYLKQVDLPVTSVTQEEQLGTAHAVAQAKSALKDFKGDIVVLYGDVPLVQPKTIKALLERLHHEDKPTVAVLAFRPDDPRQYGRIVTDKTAHIQKMVEYKDASEEERAITLCNSGLLAIRAHDLWPLLSRVQNNNASGEYYLPDIVMLALSEGRQAVTVDAEAWEVSGVNNRAELASLESLWQNRKRQDVMKDGASLIAPETVWFSYDTEIGRDVIIEPQVYFGRNVKVANGVTIHSFSHIEGADIKENVEIGPFARLRPGAEIAEKAKIGNFVEIKKSKIEKGAKVNHLTYIGDATIGAGSNIGGGTITCNYDGFNKSRTEIGEKAFIGSNSALVAPVRIGAGAIIAAGSTITHNVPDDSLAIARSEQENKALWAKKFRQRKKKK",
    "output": "Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPTIKQLIRNTRQPIRNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK",
    "output": "With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "DTTPCGESCVWIPCVSSIVGCSCQNKVCYQN",
    "output": "Probably participates in a plant defense mechanism. Not active against Gram-negative bacterium E.coli ATCC 700926 or Gram-positive bacterium S.aureus ATCC 12600 up to a concentration of 100 uM under low-salt conditions ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDTIFALATAQGKAGVAVIRLSGPRAYHTACLLAGPDLPSRGLSVRQLKDSQGARLDDGVVLTFAAPASFTGEDVAEFQIHGSLATTEAVLRCLGDLDGLRLAEPGEFTRRALENGKMSLPQVEGLADLIDAETEAQRKQAQAVLNGALGQLAEGWRAKLIRAAALLEAVIDFADEEVPTDVSPEVRALLAEVRADLEHEIAGVRIAERIRTGFEVAIIGPPNAGKSTLLNMLAGREAALTSEVAGTTRDVIEVRMDLGGLPVTLLDTAGLRETGDLVEGMGIALARRRADQADLRVFLTEDVDAMGVELQPDDLHVLPKADQRPDTANAISGVTGQGVDQLVQRISDVLKTRSSSAGIATRERHRVAMKTALDALDRTGTVLESGPDLYDIAAEELRTAIRALESLVGRIGVETLLDEIFASFCLGK",
    "output": "Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSASAPGPAPACLTLWDEEDFQGRRCRLLSDCANVGERGGLRRVRSVKVENGAWVAFEYPDFQGQQFILEKGDYPRWSAWSGSSGHHSNQLLSFRPVLCANHSDSRVTLFEGENFQGCKFELSDDYPSLPSMGWASKEVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFRNYSEFGTQAHTGQLQSIRRVQH",
    "output": "Crystallins are the dominant structural components of the vertebrate eye lens."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTAQFPPPVPDTEQRLLSHEELEAALRDIGARRYHNLHPFHRLLHDGKLSKDQVRAWALNRYYYQAMIPVKDAALLARLPDAQLRRIWRQRIVDHDGDHEGDGGIERWLKLAEGVGFTRDYVLSTKGILSATRFSVDAYVHFVSERSLLEAIASSLTEMFSPTIISERVAGMLKNYDFITKDTLAYFDKRLTQAPRDADFALDYVKRHATTPEMQRAAIDALTFKCNVLWTQLDALYFAYVAPGMVPPDAWQPGEGLVAETNSAEDSPAAAASPAATTAEPTAFSGSDVPRLPRGVRLRFDEVRNKHVLLAPERTFDLDDNAVAVLKLVDGRNTVSQIAQILGQTYDADPAIIEADILPMLAGLAQKRVLER",
    "output": "The PqqC region is involved in ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKFTKMHGLGNSYIYVDCFKELLKEEELPALAVAVADKNKGIGSDGMILICPSDRAPVKMRVFNNDGSEAKNCGNGLRCVAKFAFEHGYVKETSFDVETLGGLVKATVHPNDNGLVDTVTVNMGEPRLGRAQIPMLGEEAAEVVAEPFTIGEKEYRLTAVSMGNPHAIMFIDTIEDAPVEQVGPLLEKHEAFPDWVNVEFVQVVSPTEIHFRVWERGSGITQACGTGACAAVVASVLNGFTQKGQEVTVHLLGGDLTISWLENGDVLMTGAAETICEGTYVKGLSY",
    "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFKKFSKEDIHTRTKVKTSVQRSLKSKLVEQFPKLEEVIDELLPKKTELQIIKCSDKIQLYAVGDEVLFFQKFEELIPTLRFVHKYPEAFPTIQIDRGAIKFVLSGANIMCPGLTSSGAALPEAPGLAQDSIVVVNAENKENALAIGKLLMSTEDIKSINKGHGVETIHHLGDCLWNFSLV",
    "output": "Involved in translation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQPPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGANLLQLLEGRLDNVVYRMGFGATRAESRQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAVKMEGVFKRIPERTDLSADINEHLIVELYSK",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNTLNAPRNPTRHPAMTADTLVDAPALPHQNGSTEEKLKERGSFGKLYTYKRSPRALGIQAVAKSIGLELEQVELQPANGVPDFYWNLNPLGKTPTFVGADGLVLTECMAIALHVTNEDSTTTLLGSSSLDFVQIIRWISFTNTDVVTRMASWVRPLIGYTPYSKEEVLKAQQQTTQAIGVFEDSLRDRKYLVGDRLTLADIMCVSLVSFGFAQIFDKEWREAFPYFSGWYMMVMHLPIMKAVVEEVPFVEEGLPNAPPTEPFRAP",
    "output": "Glutathione S-transferase; part of the gene cluster that mediates the biosynthesis of the diterpene ent-pimara-8(14),15-diene (PD) . Within the cluster, the HMG-CoA reductase AN1593 functions in the mevalonate pathway, which produces isoprenoid precursors . The geranylgeranyl pyrophosphate (GGPP) synthase AN1592 is needed in the formation of GGPP, the precursor for diterpenes . Lastly, the pimaradiene synthase pbcA performs the 2 cyclization steps that convert GGPP to ent-pimara-8(14),15-diene . The putative roles of the remaining cluster enzymes in ent-pimara-8(14),15-diene biosynthesis is unclear (Probable). The cytochrome P450 monooxygenase AN1598, the glutathione S-transferase AN1595, the oxidoreductases AN1596 and AN1597 probably function as decorative enzymes (Probable). It is possible that in biological conditions the compound is oxidized to ent-pimara-8(14),15-dien-19-oic acid, which is a bioactive diterpene compound predominant in many plant extracts (Probable)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSEAKRRAAEKAIEYVENDMIIGVGTGSTVAYFIDALGHTPKRIKGAVSSSEQSTAHLKQHGIEVLELNHTGTLPLYVDGADECDPYKRLIKGGGASLTREKIIAEASKQFICIIDPNKQVATLGKFPLPIEVIPMARSLVARQIMARTDGQPVWREGVITDNGNVILDVHHLCITDPVKLEQELNQIPGVVCVGLFARRCADLVIIGSEPPHIL",
    "output": "Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAVERTFVAIKPDGVQRGLVGEILGRFERKGFKLVGLKQLAPSRELAGEHYGVHRERPFFAGLVDFITSGPVVAMVWEGDGVIASARKLIGATKPLEAEPGTIRGDLAVNIGRNVIHGSDGPDTAQFEINLWFSPEELNAWTPSDQSWRVES",
    "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGELLSFQIFINEPVELLNLSLNAKAVLPEAAVLMAMLGTLLVDLAGEKISARWSPPICYAGLGSALILLAMQWDGEIQESFLGAFIADNLAIAFRGVIVLSTLISLLISWRYADQNGSPIGEFAAILLAATLGAMLLCGSTDLVSVFVSLETLSVASYLLSGYLKRDSRSSEAALKYLLVGSAAAAVFLYGASLLYGISGSTNLKEIGTTLLSAPTPLSALALVFVLSTVAFKIAAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRILVGCFSAFDTQWKLLFTVLAVLSMSLGNVVALAQKSMKRMLAYSSIGQAGFVMIGLVCGTEDGFAAMVLYMAAYLFMNLGAFACIILFSIRTGSDQISDYAGLYQKDPLITLGLSLCLLSLGGIPPMLGFFGKIYLFFAGWADGQYLLVTVGLVTSVISIYYYISVIKMMVVTEPKEASDVVKAYPSIEWSIPGMSSLKVALIFCVLVTAIGGIISNPLFNFADSAVNGTPLLREAITLASKSSIG",
    "output": "NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTKDLNTLVSELPEIYQTIFGHPEWDGDAARDCNQRLDLITEQYDNLSRALGRPLNVLDLGCAQGFFSLSLASKGATIVGIDFQQENINVCRALAEENPDFAAEFRVGRIEEVIAALEEGEFDLAIGLSVFHHIVHLHGIDEVKRLLSRLADVTQAVILELAVKEEPLYWGVSQPDDPRELIEQCAFYRLIGEFDTHLSPVPRPMYLVSNHRVLINDFNQPFQHWQNQPYAGAGLAHKRSRRYFFGEDYVCKFFYYDMPHGILTAEESQRNKHELHNEIKFLTQPPAGFDAPAVLAHGENAQSGWLVMEKLPGRLLSDMLAAGEEIDREKILGSLLRSLAALEKQGFWHDDVRPWNVMVDARQHARLIDFGSIVTTPQDCSWPTNLVQSFFVFVNELFAENKSWNGFWRSAPVHPFNLPQPWSNWLYAVWQEPVERWNFALLLALFEKKAKLPSAEQQRGATEQWIIAQETVLLELQSRGRNESAGSEALRGQIHTLEQQMAQLQSAQDAFVEKAQQPVEVSHELTWLGENMEQLAALLQTAQAHAQADVQPELPPETAELLQRLEAANREIHHLSNENQQLRQEIEKIHRSRSWRMTKGYRYLGLQIHLLRQYGFVQRCKHFIKRVLRFVFSFMRKHPQVKHTAVNGLHKLGLYQPAYRLYRRMNPLPHSQYQADAQILSQTELQVMHPELLPPEVYEIYLKLTKNK",
    "output": "Regulates the length of the LPS O-antigen polysaccharide chain. Stops the polymerization of the chain by phosphorylating and then methylating the phosphate on the terminal sugar. This terminal modification is essential for export of the O-antigen across the inner membrane. WbdD is also required for correct localization of the WbdA mannosyltransferase."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAEDMETKIKNYKTAPFDSRFPNQNQTRNCWQNYLDFHRCQKAMTAKGGDISVCEWYQRVYQSLCPTSWVTDWDEQRAEGTFPGKI",
    "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANPSEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG",
    "output": "Binds directly to 16S ribosomal RNA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MEWIIAGLLAVIAFVGGIFYRKSIAEGKIGSAEDRARQIVDDAVKEAEAKRREAVLAAKDEVHQMRIEAERENRERRNELQRLERRLLQKEESLDRKMESMERKEDNLQRREDEIEKLRAGLAETLQKQVAELERLSGLTSEEARTLLLSNIEDEVKHEAAMMIKTIENQAKEEAEKRAREIISLAIQRCAADHVAESTVSVVALPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREVARIALEKLILDGRIHPARIEEMVEKAQKEVETRIREEGEQATFETGIHGLHPELIKLLGRLRWRTSYGQNVLKHSIEVAHLAGLMAAELGADPILARRAGLLHDIGKAVDHEMEGNHVSIGIDLAKKYRESREVIHCIAAHHGDEEPRTIEAVLVAAADAVSAARPGARRETLESYIKRLQKLEEIADSFEGVEKAFAIQAGREIRIMVKPDKVDDAESLRVAREIVKRIESELEYPGQIKVVVIRETRAVDYAK",
    "output": "Endoribonuclease that initiates mRNA decay."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAGATSSIIRENDFEDELAESMQSYNRETADKLALTRTESVKPEPEITAPPHSRFSRSFKTVLIAQCAFTGFFSTIAGAIYYPVLSVIERKFDIDEELVNVTVVVYFVFQGLAPTFMGGFADSLGRRPVVLVAIVIYFGACIGLACAQTYAQIIVLRCLQAAGISPVIAINSGIMGDVTTRAERGGYVGYVAGFQVLGSAFGALIGAGLSSRWGWRAIFWFLAIGSGICFLASFLILPETKRNISGNGSVTPKSYLNRAPILVLPTVRKSLHLDNPDYETLELPTQLNLLAPFKILKAYEICILMLVAGLQFAMYTTHLTALSTALSKQYHLTVAKVGLCYLPSGICTLCSIVIAGRYLNWNYRRRLKYYQNWLGKKRSKLLEEHDNDLNLVQRIIENDPKYTFNIFKARLQPAFVTLLLSSSGFCAYGWCITVKAPLAAVLCMSGFASLFSNCILTFSTTLIVDLFPTKTSTATGCLNLFRCILSAVFIAALSKMVEKMKFGGVFTFLGALTSSSSILLFILLRKGKELAFKRKKQELGVN",
    "output": "Multidrug resistance transporter involved in resistance and adaptation to quinidine and to the herbicide barban (4-chloro-2-butynyl [3-chlorophenyl] carbamate). Implicated in potassium uptake."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVRRRGLSGLLEADIYGITAWEYSLGRSNIEVVAQMIEAGIKVIQYREKERPARQKYEECLKIREMTREAGVTFIVNDHVDLALLVDADGVHLGQDDLPADRVRELVGDKMIIGLSTHSPAQARAAEKMGVDYIGVGPIFATKTKKDVCDPVGLEYLEFVVKNISLPFVAIGGIKEHNIAEVSSRGAKCIALVTEIVGAEDIKAKVRALRAIISRKED",
    "output": "Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPPKEAQASQKLFGTDGVRGKANVYPMTAEVAMQLGRALAFLIRNGPHRHRVIVGKDTRLSGYMLEQALASGLTSMGVDVELVGPLPTPGISNITTSMRADAGAVISASHNPYEDNGIKFFWRDGFKLPDETEGKIEELVSSGSIDSIRPTATKIGRAFRMEDARGRYIVFLKATFPRELTLEGMTIVVDCANGAAYKTAPAVLEELGAKVIALGVSPDGKNINHKCGALYPENLAKTVVKHGAHLGIALDGDADRLIVVDEKGKVVDGDAIMAICTGELVARKQLKKKMLVSTVMSNIGLERAVARWGVKVARTRVGDRYVVDEMRRNGYNLGGEQSGHLIFLDHTTTGDGTLAALQLLAVMCRAGKPLSELASIFEPVPQTLVNVVVKQKKELGELPTVMKVIKSVEQRLGNTGRVLVRFSGTEPKARVLIEGEDAARNQAYAKEIADALSKALSV",
    "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MENRWQVMVVWQVDRMKIRKWNSLVKHHMYVSKKAKGWYYRHHYETHHPKISSEVHIPVGQARLVTVTYWGLTTGEQSWHLGHGVSIEWRLRKYKTQVDPEMADKLIHLHYFDCFTASAIRQAVLGRPVLPRCEYPAGHKQVGTLQYLALTAWVGAKKRKPPLPSVTKLTEDRWNEHQKMQGHRGNPIMNGH",
    "output": "Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G. Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions. Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F. In turn, they are directed to the 26S proteasome for degradation. Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism. May interact directly with APOBEC3G mRNA in order to inhibit its translation. Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core. Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTKITLFPHNFRIQKQETTPLKEKSTEKNSLAKSILAVKNHFIKLNSKLSERFISHKNTESSATHFHRGSASEGRAVLTNKVVKNFMLQTLHDIDIRGSASKDPAYASQTREAILSAVYSKYKDQYCNLLISKGIDIAPFLKEIGEAAQNAGLPGATKNDVFTPSGAGANPFITPLITSAYSKYPHMFTSQHQKASFNIYAEKIIMTEVVPLFNECAMPTPQQFQQILENIANKYIPNTP",
    "output": "Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKN",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVAEIFNHDICENNVVISPRSETAQDNEGLFGRIGTLETRLARNEREIDAAQSVRYRVFVEEMKARLPAEAMRRKRDFDAWDSVCDHLLVLDKSIEGDSEDQIVGTYRLLRQETALANNGFYSASEFDIAGLVARHPGKRFMELGRSCVLPEYRTKRTVELLWQGNWAYAVKHRMDAMIGCASFPGVQPEAHALALSFLHHNCLAKGEWEAVALPELYHEMDLVPVEALNTRKALNAMPPLIKGYMRLGAMFGSGAVVDHAFNTTDVLVVLPVSSIAGRYISYYGGEAERING",
    "output": "Catalyzes the first step in the biosynthesis of ornithine lipids, which are phosphorus-free membrane lipids. Catalyzes the 3-hydroxyacyl-acyl carrier protein-dependent acylation of ornithine to form lyso-ornithine lipid (LOL)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVANGHFAGVGDVLDAKNYEHGVQVIDEEKEFNPNLSNYLSYENVTPAGFNYHLISVFGSQSTGKSTLLNSLFGTHFSVMSETERRQTTKGIWLSKNKRLKSDKGQDNQTKMADNILVMDVEGTDGRERGEDQDFERKSALFALATSEVLIVNIWEHQVGLYQGANMGLLKTVFEVNLELFLKDKRSNPRSLLFFVIRDFLGTTPLQNLQNTLLQDLNRIWNSLSKPAGLENSSITDYFDFAFAGLPHKNFQPEKFVDEVRKLSTRFCDGHRDPNKTDAKGTSSIEGGIFLPEYHRRIPADGFAVYAEGIWDQIVNNKDLDLPTQQELLAQFRCDEISREVLVAFDEAISPFEAKQAEAVQAGNPQVLGGLGSAMCNARMKSVKNFDTEASRYHKRVYQMKKSELQDKIDSRLKALFLGQLSAAHRSGIQEFTESVTAAVKAGQKRGASYDFAEIVTKERKLAIEKFEKEARAAVVEDTQWSNYQQELSLYQKDLENIGGQLRRDEMRRLATRVGRWVRSRLGESIDLEFNAIGSGRGGSGAPEFGDKPSEKSLWDRVWTLFVDTVLDAERRFTERASSFDASIDEVDVGLWRLRRKSWGVLRAKIEEEMMEGNILLKLRENFEDKFRYDDAGVPRIWRPNDDIESIYTRARESTLTLIPLLSRFRLAETNAPPPLDKWIGHTPSSATPADEEDLTPIGGVDEDEGKSLEEEMTMIGEAKKQDLTVRFKKTADGVYVEAKRSAIGGITQVPLYFYGLLLALGWNEIVAVLRNPAYFLLLFVCAVTAYVTYQLNLWGPIIKMTEAASQQALMEGKRRLREFLEASDTGLQAMAMSEGRNAEEYDMSNMKNRKSAGGFQNNRSHIDDADDDDDF",
    "output": "Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSDIDFGYTKDHARKGANAKLPEIQCWENQYKRDYDIRIELPEFTSVCPKTGLPDFGVITIDYIPDRLCLELKSLKYYLLEYRDMGIFMENIANKILDDVVKACKPKKAVVTGDFTPRGGLRSVIVAKYEKK",
    "output": "Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKFIDEAKIEVAAGKGGNGATSFRREKFVPRGGPDGGDGGKGGSVWAEADENTNTLVEYRFVKRYQAKNGEKGHGSDRYGAGADDIVLKMPVGTLIRDLDTGETVADLTYHGQRVCLAKGGKGGLGNIHFKSSVNRAPKQSTPGEEGEARSLQLELKVLADVGLLGMPNAGKSTLITAVSAARPKIANYPFTTLHPNLGVVRIDENHSFVMADIPGLIEGAAEGAGLGHRFLKHLSRTGLLLHVVDLAPFDETVNPAEEALAIINELRKYDEELYGKPRWLVLNKLDMLDEEEAQTRTAAFLEAVGWDYPKPDDRFQFDMETPRLFQISALTHQGTQELVHQINQYLTEKKRIEAEKAEAEKAAANVEIIEQQPKTDTGVFKPE",
    "output": "An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPRNPNSFRLTARNIFLTYPRCDVPKEEVLEMLLHLSWSVVKPNYVRVAREEHSDGSPHLHCLIQLSGKSNIKDAGFFDLTHPRRSARFHPNIQAAKDTNAVKNYITKEGDYCESGQYKVSGGSKSNKDDVYHNAVNAGSAGEALDIIKAGDPKTFIVNYHNLLANVERLFQKPPEPWVPPFELSSFTSVPEELQDWADDYFNECSAAARPTSIIIEGGSRTGKTMWARSLGPHNYLSGHLDFNSRVFSNDVKYNVIDDVAPHYLKLKHWKELIGAQRDWQSNCKYGKPVQIKGGIPSIVLCNPGEGSSYKDFLDKAENSALREWTEKNAKFIFLEGPLYQSTAQDC",
    "output": "Essential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNYIRILVGDRVTVEMSPYDLTRGRITYRFK",
    "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRGFRPLLSLLLPLSACFPLLDRRGPTDIGDIGARMNWAQLAEGHPPNSVQNPQPQALLVVAREQQASHREHTGFRLGRQDGSSEAAGFLPADSEKASGPLGTLAEELSSYSRRKGGFSFRFGR",
    "output": "Stimulates feeding and grooming behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDASTAHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNPEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLNINGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTNGERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGSEIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQRSSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPYPAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDALGLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVPTDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKPSVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPFLEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPSKLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAMMRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERCEYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSGDSSHTETTAEEVPEDPLLKAKRRRVSKDDWPEREMTNSSSNHLEDPHYSELTNLKVCIELTGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW",
    "output": "Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKSFSLLASAGLATLASLPLTMAGVITPSYFDKHPLSRRQLSDAQVQRELGPQLSRGATIIGPGGPGWDDAIERFDNESRPTIRLVVVPAVESDIATVVKLANRFGIPFLVKNRGHALTNTIGRFRGIQIDMSRLTTITIQPGEPAESAWFQGGAWDKQAIEYLWDRGYVTVTGSCDCVGMMGPGLGGGHGRYQGLYGLISDNLINMNVVLADGSAVRVNATSNPDLWWGMQGAGHNLGIVTSFQSKIYPRKIDTWHYHSYTYTQDKLEAVFGALNTFHGNGDGSTPVLMGLNTGGFYIDPSVSQTEPVVSWVFGYAGPASEAEALLEPFSRLGPAAEQSGDVPYPGVATAMGTGQDQPLCQPGDAHVQVTSQFNVYNATAERALYQLFNRTIAAHPQLADSVAFHEGYSTAAVDRADPSASAVAFRDRKLLMFFDARLKPADAADPEVLGMAREFGRQVRRIWNEGAPDLKPATYVNYAAGDEPLESMYGYDAARLRRLRNIKRKYDPHGRFVYYNPIA",
    "output": "FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of pyriculol and pyriculariol, two heptaketides that induce lesion formation upon application on rice leaves but are dispensable for pathogenicity . The highly reducing polyketide synthase synthesizes the heptaketide backbone of pyriculol and pyriculariol . Pyriculol and pyriculariol contain several hydroxyl moieties and double bonds, so it can be assumed that several reduction steps occur during biosynthesis. These reactions could be executed by PKS19 itself or partly by the tailoring enzymes OXR1, OXR2, RED1, RED2 or RED3, identified within the cluster (Probable). The FAD-linked oxidoreductase OXR1 is the only tailoring enzyme for which the function has been determined yet, and is involved in the oxidation of dihydropyriculol and dihydropyriculariol into pyriculol and pyriculariol, respectively ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEKSITNSPVLSILSYCAASILMTVTNKYVLSGTSFNLNLALLAVQSIVCLTAISIGKSFGLCKFRSFNADEAKKWFPIALLLVVMIYTSSKALQFLSIPVYTIFKNLTIILIAYGEVLWFGGSVTSMALASFVLMVLSSVIAAWSDISGAIAVSGSATTTVTALNIGYFWMMSNCFASAAFVLYMRKRIKLTNFGDFDTTFYNNLLSIPVLLIASLLFEDWSPANLAVNFPPESRNLIFFSMVVSGLMSIGISYCSAWCVRVTSSTTYSMVGALNKLPLALSGIVFFGTPATFSSVSAIFVGFVAGIVYAVAQIQKKKAEAALPK",
    "output": "Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRKVIICSPRGFCAGVIRAVQTVERALEKWGAPIYVKHEIVHNRHVVDKLRAKGAIFIEDLQEVPCNSRVIYSAHGVPPSVREEAKERGLITIDATCGLVTKIHSAVKMYARRGYLIILIGKRKHVEVIGICGEAPDKITVVENIAEVEALTFSTKDLLFYVTQTTLSMDDSADMIAALKARYPQIITLPSSSICYATQNRQSALRNILPKVEFVYVIGDPKSSNSNQLKAVAARRGVVARLVNNPEEITDEILQYSGNIGVTAGASTPEDVVQACLTKLQKLIPTLVVETDLFVEEDTIFQLPKELQ",
    "output": "Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLLYRGAPAGPGTPGGGLARAGSVPQAFRIRLSTMSPRYLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVFIDVEEVKKKPCLTFTDDGCGMTPHKLHRMLSFGFTDKVIKKSQRPIGVFGNGFKSGSMRLGKDALVFTKNGNTLAVGLLSQTYLECIQAQAVIVPIVPFSQQNKKMIVTEDSLPSLEAILNYSIFNCEKDLLSQFDAIPGKKGTRVLIWNIRRNKDGKSELDFDTDQYDILVSDFDAEEKEIGGVTSELPETEYSLRAFCSILYMKPRMKIFLRQKKVTTQMIAKSLANVEYDIYKPTSTNKQVRITFGFSCKYHNQFGVMMYHNNRLIKAFEKAGCQLKPTCGEGVGVIGVIECNFLKPAYNKQDFEYTKEYRLTINALARKLNAYWKEKISQENFEPLPTSRRIPDQTWVQCDECLKWRRLPGMVDPSTLPARWFCYYNPHPKFKRCSVPEEQERIDEDLHRSKAKQQVEAAEKKQKPMESDKYQVFSNPPKTPPLQDMAELNDKTIGYEQINSPSLLPSVREESRSPPRLKSLDSSAFQISRKYKLILGEEPVEKRRKIQTEMPLSPIDYSMSGFYRRVEAATAYPEGENSPDKCSSERSTPPHLIPEYPESNKHTEENREAPALCPGSQDQDQGFLLPEELEDQMPKLVAEESNRSSENIDKDMNKGPFVAVVGVAKGVADSGAPIQLVPFNREEFVGKRKRAESWKRANPYSSAAPAATAGKGKDCQDSRSRNMPKIKTPKESEELKRTTEKLERVLAERNLFQQKVEELEQEKNHWHSEYKKAQHELVTYSTQETEGIYWSKKHMGYRQAEFQILKAELERTKEEKQELKEKLKETESHLEVLQKAQVSFRNPEGDDLERALARLTRLRVHVSYLLTSVLPHLELREIGYDSEQVDGILYTVLEANHILD",
    "output": "Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3 (By similarity). The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0 (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSSYSYTVAETQTFSVTHARHMAAKVATDLRRMQRFYGYPSDADIEAYEEELVVFLKAGYLGEVSYGFQKNNNWIEPTLRYTAGDLLGSGTDDDPGKIRPGKDVSGASFYSFMTYSSKYLNATQSEKDTALKDLPFKRVGAQSPGINGYLENDKTYSAGGRSLTRTSVRNFV",
    "output": "CBASS (cyclic oligonucleotide-based antiphage signaling system) provides immunity against bacteriophage. The CD-NTase protein synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals. The signals activate a diverse range of effectors, leading to bacterial cell death and thus abortive phage infection. A type III-C(AAA) CBASS system .; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAETGKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKILADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGLIEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLMERPQIIVANKMDMPEAQDNLKAFKKKLATQYDEFNDLPMIFSISSLAHQGLENLLEATAELLAKTDEFLLYDESDLVDEEAYYGFAEAEKEFEITRDDDATWVLSGEKLERLFVMTNMERDESIMKFARQLRGMGVDEALRERGAKDGDLVRIGKFEFEFVD",
    "output": "An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRDLKTYLSVAPVLSTLWFGALAGLLIEINRFFPDALTFPFF",
    "output": "May help in the organization of the PsaE and PsaF subunits."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRARRGLLRLPRRSLLAALFFFSLSSSLLYFVYVAPGIVNTYLFMMQAQGILIRDNVRTIGAQVYEQVLRSAYAKRNSSVNDSDYPLDLNHSETFLQTTTFLPEDFTYFANHTCPERLPSMKGPIDINMSEIGMDYIHELFSKDPTIKLGGHWKPSDCMPRWKVAILIPFRNRHEHLPVLFRHLLPMLQRQRLQFAFYVVEQVGTQPFNRAMLFNVGFQEAMKDLDWDCLIFHDVDHIPESDRNYYGCGQMPRHFATKLDKYMYLLPYTEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVQNAGYSVSRPEGDTGKYKSIPHHHRGEVQFLGRYALLRKSKERQGLDGLNNLNYFANITYDALYKNITVNLTPELAQVNEY",
    "output": "Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) . LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). Plays a role in the glycosylation of BMPR1A and regulation of its protein stability (By similarity). Essential for extraembryonic development during early embryogenesis (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTRTASITGACMALADALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLLALARGGIESIVATQKAALAN",
    "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MALSDSIGDFLARIRNAQLAMHKTTRVLFSKVNSSILKILKDEGYILDYQKEVVGNIPSFVVKLKYYERSPVISDIVRVSKPGCRCYSKYKDISKAYNGLGIFIISTSKGVMTDYDAHKLKFGGEILCRVF",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ",
    "output": "dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MMKGGMAGLMKQAQQMQEKMAKMQEELANAEVTGKAGGDLVTVVMTGRHDVKKVSIDPSVLPGLDEDDREVVEDLVAAAVNAAVRQIEANSQAKMGSMTAGMNLPAGMKLPF",
    "output": "Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQIIEIREPEQADFKQERQIAVGIDFGTTNSLIAIAANRQVKVIKSIDDKELIPTTIDFTSNNFTIGNNKGLRSIKRLFGKTLKEILNTPALFSLVKDYLDVNSSELKLNFANKQLRVPEIAAEIFIYLKNQAEEQLKTNLTKAVITVPAHFNDAARGEVMLAAKIAGFEVLRLIAEPTAAAYAYGLNKNQKGCYLVYDLGGGTFDVSILNIQEGIFQVIATNGDNMLGGNDIDVVITQYLCNKFDLPNSIDTLQLAKKAKETLTYKDSFNNDNVSINKQILEQLILPLVERTINIAQECLEQAGNPNIDGVILVGGATRIPLIKDELYKAFKIDILSDIDPDKAVVWGAALQAENLIAPHTNSLLIDVAPLSLGMELYGGIVEKIIMHNTPIPISVVKEFTTYVDNQTGIQFHILQGEREMAADCRSLARFELKGLPPMKAGYIRAEVTFSIDADGILSVSAYEKISNTSHAIEVKPNHGIDKTEIDIMLENAYKNAKIDYTTRLLQEAVIEAEALIFSIERAIAELTILSSESEISIINSLLDNIKEAVHARDWILINNSIKEFKSKIKKSIDTKFNIIINDLLKGKNINQIK",
    "output": "Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEKVKFEKRESLKEKPDTANLGFGQYFTDYMLSVDYDADQGWHDMKIVPYAPFEISPAAQGLHYGQAVFEGLKAYKHNGEVVLFRPDQNFKRINNSLARLEMPEVDEEALLEGLKQLIDVERDWVPEGEGQSLYIRPFVFATEGVLGVRSSHQYKLLIILSPSGAYYGGDTLKSTKIYVEDEYVRAVRGGVGFAKVAGNYAASLLAQTNANKLGYDQVLWLDGVEQKYVEEVGSMNIFFVENGKVVTPALNGSILPGITRKSIIQLAEDLGYEVEERRVSIEELFNAYDKGELTEVFGSGTAAVISPVGTLRYEDREIVINNNEPGKITQKLYDTYTGIQSGKLEDKYGWRVEVPKY",
    "output": "Acts on leucine, isoleucine and valine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSRKESRTQAFQTLFQLEMKNSDLTIEEAISFIKDDNPDLEFEFISWLVTGVKDHEVVLDEKIQPHLKDWTLARLLKSDRIILRMSTFEMLHSSTPQKVIINEAVELAKQFSDDDHYKFINGVLSNIE",
    "output": "Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAPSAVGLLVFLLQAALALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCADILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYENGDFCIPLCTEECMHGRCVSPDTCHCEPGWGGPDCSSGCDSEHWGPHCSNRCQCQNGALCNPITGACVCAPGFRGWRCEELCAPGTHGKGCQLLCQCHHGASCDPRTGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGTFGFLCSQRCDCHNGGQCSPATGACECEPGYKGPSCQERLCPEGLHGPGCTLPCPCDTENTISCHPVTGACTCQPGWSGHYCNESCPAGYYGNGCQLPCTCQNGADCHSITGSCTCAPGFMGEVCAVPCAAGTYGPNCSSVCSCSNGGTCSPVDGSCTCREGWQGLDCSLPCPSGTWGLNCNETCICANGAACSPFDGSCACTPGWLGDSCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSRGPCHHISGICECLPGFSGALCNQVCAGGHFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPSGFWGSACFHTCSCHNGASCSAEDGACHCTPGWTGLFCTQRCPSAFFGKDCGHICQCQNGASCDHITGKCTCRTGFSGRHCEQRCAPGTFGYGCQQLCECMNNATCDHVTGTCYCSPGFKGIRCDQAALMMDELNPYTKISPALGAERHSVGAVTGIVLLLFLVVVLLGLFAWRRRRQKEKGRDLAPRVSYTPAMRMTSTDYSLSDLSQSSSHAQCFSNASYHTLACGGPATSQASTLDRNSPTKLSNKSLDRDTAGWTPYSYVNVLDSHFQISALEARYPPEDFYIELRHLSRHAEPHSPGTCGMDRRQNTYIMDKGFKDYMKESVCSSSTCSLNSSENPYATIKDPPILTCKLPESSYVEMKSPVHLGSPYTDVPSLSTSNKNIYEVGRCLT",
    "output": "May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MESSIFKPSSMDLIRAGLQDLDKARALFDQLKADDIPDERCAELLSALAHACDPDMALSNFVDIVNAMQSSQRDLEHVIPDNDALKRLVTVLGVSDAMGKFMRFKPQLVEAAAVDNCNSHLFNHAQRRARLLKAVGADPDEPAMPVASKDLAEAATALRSSYRNQLAAIIAQDAVADDPTSIQPTISRELSDLADAALEGALAIARHETEGSEHVRFTIIGMGKLGAQELNYVSDVDLIYVVEPADKDVDHQTLIRVGTKMGTMLQRVCQSAIMGVAEQPLWQIDGGLRPEGKDGALVRVLSSHKNYYEQWAENWEFQALLKARPVAGDPDLGQAYMDMTRPFVWSASKRKNFVYDCQKMRKRVEDLIPAPLKDREIKLGRGGLRDVEFTVQMLQLVHGRTDESLRTSNTLDSLQRLSEGGYVSRKQAVRMSQDYRFERVMEHRQQIWSLKRTHLFPDLGRASVGGLEKKRDIDVDELNQNQELRRLARAFGLHPEELVDKYDDTRREVRHLHLDIYYRPMLPVNAQMENDQIVLSVEAAQERFESIGFGDPDAAIRHVQALTAGVGRAAKINRIILPAVLQWLGEGQNPDMGLLNWRKLEENFGTESGYLGFLRDSTSAAQRLCHILSNSRFLGDALNKSVESISWLGDDDNLQARTREALDVQTGSALERFGSNINEFATSMRAMRRHEIERIGLSWMSGVISDSDSLKAMTDVYDAIIDASLTWAVRHQIAEFGVETAPAGITVIAMGRYGGREVNFSSDADAILIYRPADDADDGQANAFAKKVVEDLRNILQGPTTLEPKIELDLDLRPEGKNGPLVRSYASCEEYYESWASTWERQALLRARYAAGDAELARDFLINIADPLRYPTTELTEAELQNIRKLKARMEAERLPRGVRRERHLKLGKGGLSDVEWTVQLMQLQHAGDIKDLRVNGTLEALDVLEAKKLISAIDAIQLRKAWTLCTAARNGSYLWSGRANQADILPDDIYSLGGIAVYLGYGAHRGQHFENDLLAVMRKCRDVCQRLFYGKTEGEAAAATTATASAATQQPQTAPRPRMHVIAPRLERNRRRAQR",
    "output": "Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITHISEEGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFFLGWQGLPGRGRALGSGEVKFFGQVLPEAKKVTYNIHIKRVLKGKLNMAIADGSVSVDGREIYTAEGLRVGVFTSTDNF",
    "output": "Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MANRVVLDFEKPLFELEAKLEEMRVYLRNSSRDQDSSDQDVLNREIEALEVKVETLRRSIYKNLTRWQKVQLARHAERPFTLDYIYMMTRDFVEMAGDRYFSDDKAIVGGFAILEDIPSGFSQPVMIIGHQKGRDTKSNLYRNFGMAQPEGYRKALRLMKLAEKFNKPVITLIDTPGAFPGIEAEERGQAEAIARNLFEMARLTVPVICVIVGEGASGGAIGLGVGNRILMAENSWYSVISPESCSSILWRSWNYKEQAAEALQPTAEDLLAQGIIDRIIPEPMGGAHTDPEAMAGTLKEMLIEELRILMSKESDVLVRERVEKFSGMGVWDE",
    "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MLIPSKLSRPVRLEHTVVRERLLAKLSGANNYRLVLITSPAGYGKTTLISQWAAGKNDLGWFSLDEGDNQQERFASYLIAAIQQATGNHCAASEAMVQKRQYASLSSLFAQLFIELADWQRPLYLVIDDYHLINNPVIHDAMRFFLRHQPENMTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLTSPIEADDSSRLCDDVAGWATALQLIALSARQNNSSAQHSARRFAGINASHLSDYLVDEVLDNVDARTRNFLLKSSLLRSMNDALIVRVTGEENGQMQLEEIERQGLFLQRMDDSGEWFRYHPLFGSFLRQRCQWELAVELPEIHRAAAESWMAQGFPSEAIHHALAAGDAKMLRDILLNHAWGMFNHSELGLLEQSLAALPWSNLLENPRLILLQAWLMQSQHRYSEVNTLLARAEQEMSVEMDTAMHGDFNALRAQVAINDGDQDEAERLSMVALEELPLANYYSRIVATSVHGEVLHCKGKLTKSLAVMQQTEQMARRHDVWHYALWSIIQQSEILFAQGFLQAAWESQEKAFQLVREQHLEQLPMHEFLLRIRSQLLWAWARLDEAEACARQGMDVLSTYQPQQQLQCLALMVQCSLARGDLDNARSHLNRLENLLGNGHYHSDWVSNADKVRVIYWQMTGDKTAAANWLRQTPKPEFANNHFLQSQWRNIARAQILLGDFEPAEMVLEELNENARSLRLMSDLNRNLLLLNQLYWQSGRKSEAQKALLEALTLANRTGFINHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILRDINQHHRHKFAHFDEGFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV",
    "output": "Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKIIELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG",
    "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTQAEKGDAENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQSNFIVVIHPGSTTLRIGRATDTLPASIPHVIARRHKQQGQPLYKDNWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNKWTNTSHHPEFLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATFGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHAQEVDLGSSQGDCLMAGNESEEALTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW",
    "output": "Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize (By similarity).; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRSNLPLNALRAFEASARHLSFTRAALELCVTQAAVSQQVRILEDRLNRVLFKRLPRGLEMTDEAQALFAVLTDAFGQIDTIFRQFEGGEYREVLTVAAVGTFAVGWLLPRIEQFRQAHPFVELRLRTNNNVVNLAAEGLDFAIRFGNGLWPATHNEMLFEAPLTVLCTPETAQRLRRPADLLQENLLRSYRVDEWDNWFAAAGVTAERINGAVFDSSRLMVETVIHTGGAALVPAVMFARELAAGQLVRPFDIEIQMGYWLTHLKSKPMTPAMEIFRDWIVKMA",
    "output": "This protein is a positive regulator of gene expression of beta-lactamase (AmpC)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAGPFSRLLSARPGLRLLALAGAGSLAAGFLLRPEPVRAASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQDIRIPTPVIHTKH",
    "output": "Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRKRGLQVHARVRPVLNIGIVVGVLLGGVVLLQPFYLIQEGQVALITQFGEIIKTNNTAGLYVRAPFLHHVHKYTAKLLRVDGDPQKIPTKEKQFIEVDTTSRWRIEDVKKFYQSLGTYEAAYSRISDIIDSSVRDIITVNGLDDVVRSTNAINESNHSEQFDVPVSQLAFDRGAEKTAHMTIEKGRESLAREISQAANDQLKDFGIVVVDVIFKGIKYSDELQASVFNRMVKERNQIAQMFRSTGEGKKAEWLGKLDNEKRSLLSKAYEEAERIKGEADARAAAVYAQSYGKSPEFYGFWKSLEVYKKSLPDTEKILSTDLEYFKHLYQH",
    "output": "HflC and HflK could regulate a protease."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQKDYMKLHSNSDFDADQLDEHDDNVFQDVYDTGFDDGYIKANQENLIANQYKKLDKNSYQNGNNSFYTKDELEKLKKQSFQVNQDIDYYQQAQTEISSERQRLLQAIDDLEANQDQFHPEDFQAERQYLINELDRLDSELYHIEQYKNDSIDFVNELNQRLSAEQAKIDSYNSSLDKNIRKDYIQIDQLKNKLAEETTEYNDLLNRSTDEISEIDRQSERLQNLIDERIAKLNNDSYGVSSLDSSTRERLKKEIHDLSEQRKKLQSAKKLHLYNLNLKKESIRRYRSQLEQYLESLKQMRNEHNKKLKGYAQNLDNIKNEVEKAKQNFNDQQLKILQSKANADQYFALRKIELENSYKKAKNAILEANKAHAKNVQEEQALANKNNKTQRLLNKLKEDYDRLKIASLSFESMRKQSLAALNNLQDELKQKHNLLERKKHEQDGIVNEKISELEGYRSDLVDQKLKIEREKENQERRYKAAEASLNKKRQEIDELFLEANTKLNEASLKENDLNNQKREILAKLRNLEHLKSEIDQRRRDLDQRELIDQQTIRKIQLDVESERADLQRILLIERKKNDERQQELLQYERDIKRQQTDFENTVNWEQKKLSQREKELKDGYEQLQLKQSEVQEKIDELNEEINRAQKSKQNSLVLEQKLKSDLEHLNLSKNYLDKQQEELNQKSDKMIEDLKVFERDLKRQKEDLSIYEKSLQQKEASLINFQNDVTVQKNEAYHKAQAIHQELELKKAAIENELRKLTAERKAVDADKEENTKLKKFIDEEIRSLANERKELEIYQNNIENFKNNAVDRLNVLESDLVKKRNELEQLKKEQQTHYNELNSNLTNELQELEEQKKKFAHQKQQKFEELLQAKNNLSIKENELVLYAQKVNDRYNELKAIEKSNTAKSEMINAKLEEFKHAEIDYLNYQNKIKQEQIKFDNQVKILESQYNQRNEILLIREEQIKQKKAEQQAQEKQIQKDFKRLQEEKNNFDDQKRNKFNKISNLYLEIKKQRDEVDLAQRQIEDQKEELLIKAREGRLQKQEIEDRLAVLEKSEKRFRQEDELLAKKRIDLIERIGVLKADINKKHEILSLRSVQLTEKAKKQQEKDADLQRKFDLLESEVERFNEEKKSEFQKLKVERDKLAHREKNVSKNMNEINLALAKLDLIRKNNKVDKAKINEKLALLNDQKEKIDRENDLLDAKKTEVITRLRKMENDLEFEKQKVLLDRSNIERISSDQQALARELETKYQTLEREKRSFSQRKENELKEIDDFYQQVQHKERTLNLKIEDLKQLRYLLEKESYNVNVNKKDLKVRIEHYQRLERAIKNEQHKLNNQKNNFFNKVELLNDQLNKKSSKIALLRSKIYNTYKQQQQQKQILLEEKHKNSQLRKSLLKTQEELHQQKAQFSIAKKQEEKKLKNQKDLIQNTLSEVIKQKDQITNIKQEVDLKQTQLNNLEKLIIKQRADLQKELEKNSENTYRLQKAERLLEEKKTKLRLEYDKAKKVLSTAKATDQALKTKQAKVQDQFKKLVLINKKIIEARNNLLKQRNIIQKEINNRNMANFQNPYPNFLNLAPNTQVVPAQTIMPVQTPQLVGVNYPNQPAFDFNNPLMQMQQLINQQQMLMMQKEHQWALEEANKKNSRLAKQLKQLKHHKQALTESTSEHLNYHNLLNADNSYKINSLQNLLSKVAYNTKRRINQLEHNLDPETADLNQLHELNANSQLLDEIRTVLSNTTTNTNAVVPANSYSKELRMLFDEIKADFKKQAVLFNTQKEVFTNQINQLAQAVEQGPIEVRKTLESQDQKYQQMFDNFRDAYEQNISLLRNENNEVQKKLTDLYDEIAAIKTNTEKIKKTTLRPEVRNNANEGLASFNSVNRDKKDYLDQTLPVHQNLRIDLNQNRDLSHAKKERINQLANEIKTIKELIEKRKQTSL",
    "output": "Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEKTQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRINKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQALAAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFISVRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQPAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFSKEEFASAAKN",
    "output": "Catalyzes the conversion of lactate to pyruvate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAYGTRYPTLAFHTGGIGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELFGNIVPVDTCVKSFKHGAVLEVIMAGRGAALSDGTHAIATGIGICWGKDKNGELIGGWAAEYVEFFPTWINDEIAETHAKMWLKKSLQHELDLRSIAKHSEFQFFHNYINIKQKFGFCLTALGFLNFENAEPAKVN",
    "output": "Part of the AaxABC system, catalyzes the decarboxylation of L-arginine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPIGVPRVRFQYRRDRSRVWIDIYNRLYRERCLFLAHVVESQIANQLVGLFIYLGVQDETKDIFLFINSPGGGIISGFAIYDTMQFVRPDIQTICVGLAASMGSFLLVGGAITKRLAFPHARVMIHQPMSAFFETQTVEAILEAEELLKLRESLAKVYVQRTGKPDWVIAEDMERDVFLSATEAQSYGIVDVVGVALASKG",
    "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAVTSFPADSLASMESVKQTVRSTSTCSAATVLSLQTLFRSAGEMETTLRRTARGTKATATNATASSRAKTTRTKSTSTSTTRTKTPAQDVSTFTSTSASLADTRLSNQEKLVLATEVFNSTLKTLSDAVKTVMSISKEKKDASPTKRGTTTKGRVKTSQPDLTDNENGVSAVAECARLSLSCLRMLRTDAMVDGGLPNLQLEQGACVLAGRLLALGLNDAAYKELRGLKRRIQSYLEELPSGRKRTGRKDAEDGEETAKERMSDLLSFSDIANARSIHGLLVSFQSNALRLIAAEKRPATVQKLVPSLQLTDESSPANVIMASIDSGALTKDKAAVQLQLLSSTVLSLSASGASTGKERLRPSIVLSLQLLALEIRCMSWKLSGHACEDNKEMWDPLARYIGAFAQATKSIEKAEFAVIYKNIVRLQSAFSKTQNCATRSTDNLSVARIATILGQLAQDAGCFDEALQLFTESLNPLSSSQCLGMATVRCKIAALHFQAFKSSVKLPGDVSDAVSQATAALSISLKGSSHDLDELLVQAAKLKKLAMGWFGDLISKGQGSQCENVVFPRICEFLSSFVRFLRRYIGRRPENDELNDREIFQKRIDAAQNIVLAAVDSTIAIGKLSVMSQRPAWEETVSTLLDCQRLLATIEPFDEVDVATADSIDQALVKLSNLFWSRYLKEKEAGKNARELLPLLKQSAYLLSGCSPSQRATGFAPLKYERLAHTYIEGNMVSEAEVAFRQSITDHIAAGALDKIASSTDGCFPHQMNQDPKRSGFTLGRVLSAYLKVKLRNKRSAVNEIFDDETLPSVQRGHVLEWQLGILTEIHGTSNNDNVFRSVFAEVATRLFKVYPAEQHPVRRLRVLLSGLRFALEQPGFLDSSLLQRFADEGRKGLDDDDYQDDDDIKSLAVYLKNSVRLTLGLQQGSLGPEELELIVSTWTSILRFCHDLKSLVACVGNVEYFLLQMKAVVDYTEIHGLWKFQLSTLELVLRVTELHGAGTFSEAIIVLSRLVLQYCRMGFCIKAHSLLSRADGYIANHEVSCLARLSYELARVGFLLETGDNQKAATVLSTARMIYEKHQATEDLDACSVLTKISWERLVADAAFMSSRLSFAQGSIKDALYFAKLSVRLNCRIWAKVEKLAQKKQEKAVVGDSSELEIVVEGMAKLEVSQTSSTYSQGAPFWPHIGSHHSSLLHLANLSAHHGLFQDAIYYGEQALKINKSLNANVRLIASQAHLGSHWILGGHISEGQQLLASAKALSDKLGSSIELVSLRLSLAALHRVEGDYRNEYRTLREAEKLLGGLFESQADSADIPDLEEKMDKLRVRPKSRSTRQPATTATRRTRSATTSARSTPKPPQSVEATNASNTLLQMKSEILLQQAASLRAQREFEAASTLLSDARKFAVTRNSRISVHLGESEHLLADAIRNFANHAVYCVLPESTISLPSLEPKAASESSSKSATRKTRAPTRGTRTKAQAATEDFSVMLSKAGDCLNGIFDTATQLGSTLDSHSASRLMSRISMLSHVTASPNHILWPHSPANMNEVGRIGAFARERAAIRIDKRLADYCDPLLWPRSELESEGVSPDFTKEYVDILPDNWNVLSLSLSADRAEFVVSRLHRGCSPFLLRLPLRRGNSEDEEEQFTFEDGRDEMKELIRLANESAHAAKLQVDRQMKKEWWKNREALDRRMENLLQNIENVWFGGFRGIFSPIPLCEKSLARFASAFENILENHLPSRRKGSRAQGPKLTLHPNVLELFVGVKGLDDQEDPEDTLMDLLYFVVDILQFQGERNAYDEVDFDMMVVETLDAVRAYHEAAKDQATQRPNNTVLVLDKSLHLFPWESLPCLQGLPVCRVPSLECLRDRVLHLRSGKQSALSIDRRNGTYILNPTGDLKTTQETFEKDLSSLKGWTGMVNRQPTEDEFKDSLQSKSLFLYFGHGSGAQYIRGRTVKRLDRCAVAFLMGCSSGTLTEAGEYEPYGTPMNYLQAGSPALVATLWDVTDKDIDRFAKATFEHWGLIGNGHRGNEGIGEAGVALDAAVSQSRGACVLKYLNGAAPVVYGVPGVFLH",
    "output": "Required for nuclear division. Could function in the mitotic spindle."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSWQTYVDEHLMCEIEGLHLASTAIIGHAGTVWAQSTAFPQFKPEEITGIMKDFDEPGHLAPTGMFVAGAKYMVIQGEPGAVIRGKKGAGGITIKKTGQALVVGIYDEPMTPGQCNMVVERLGDYLLEQGL",
    "output": "Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKKVFKRLEKLFSKIQNDKAYGVEQGVEVVKSLASAKFDETVEVALRLGVDPRHADQMVRGAVVLPHGTGKKVRVAVFAKDIKQDEAKNAGADVVGGDDLAEEIKNGRIDFDMVIATPDMMAVVGKVGRILGPKGLMPNPKTGTVTMDIAKAVTNAKSGQVNFRVDKKGNVHAPIGKASFPEEKIKENMLELVKTINRLKPSSAKGKYIRNAALSLTMSPSVSLDAQELMDIK",
    "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSEIKLNYHKTHFLTSAPNIRSIPEDTGIEIAFAGRSNAGKSTALNALTNQKNLARTSKTPGRTQLINLFEVEPNYKLVDLPGYGYAAVPEQMKIQWQKSLGEYLQKRECLSGLVVLMDIRHPLKDLDQQMIEWAVSADLPILLLLTKADKLSQSARSKQVKMVREAILPFQGDIQVEAFSAQNKIGIDKLAAKLDFWFSPLFAK",
    "output": "Necessary for normal cell division and for the maintenance of normal septation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAFPDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTVHNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAENKRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK",
    "output": "Synthesizes alpha-1,4-glucan chains using ADP-glucose."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQAFRVHTGIGVPLRRSNVDTDQIIPAVFLKRVTRNGFEDGLFATWRVDPSFVLNLSPFDRGSVLVVGPDFGIGSSREHAVWALMDYGFRVVISSRFGDIFHGNAGKAGLLAAQVAQDDVEFLWKLIEQKPGLEITVNLQDRNINAATVVLPFKIDDYTAWRLLEGLDDIALNLRKLDEIEAFESARPAWKPRTLPTT",
    "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSVISTLRDRATTTPSDEAFVFMDYDTKTGDQIDRMTWSQLYSRVTAVSAYLISYGRHADRRRTAAISAPQGLDYVAGFLGALCAGWTPVPLPEPLGSLRDKRTGLAVLDCAADVVLTTSQAETRVRATIATHGASVTTPVIALDTLDEPSGDNCDLDSQLSDWSSYLQYTSGSTANPRGVVLSMRNVTENVDQIIRNYFRHEGGAPRLPSSVVSWLPLYHDMGLMVGLFIPLFVGCPVILTSPEAFIRKPARWMQLLAKHQAPFSAAPNFAFDLAVAKTSEEDMAGLDLGHVNTIINGAEQVQPNTITKFLRRFRPYNLMPAAVKPSYGMAEAVVYLATTKAGSPPTSTEFDADSLARGHAELSTFETERATRLIRYHSDDKEPLLRIVDPDSNIELGPGRIGEIWIHGKNVSTGYHNADDALNRDKFQASIREASAGTPRSPWLRTGDLGFIVGDEFYIVGRMKDLIIQDGVNHYPDDIETTVKEFTGGRVAAFSVSDDGVEHLVIAAEVRTEHGPDKVTIMDFSTIKRLVVSALSKLHGLHVTDFLLVPPGALPKTTSGKISRAACAKQYGANKLQRVATFP",
    "output": "Catalyzes the activation of long-chain fatty acids as acyl-adenylates (acyl-AMP), which are then transferred to a multifunctional polyketide synthase (PKS) for further chain extension."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTLSDSDLELITTELGRELTPAEAALFENLWSEHCAYRSSRPLLQSFTTGDDSANDEGAEHVVIGPGDDAAVVRLPRVDEASETPIYITMGIESHNHPSYVDPYDGAATGVGGIVRDTLSMGAYPIALADSLYFGSFDRERTQYLLDGVVEGIADYGNAIGVPTVAGSVEFHNKYTGNPLVNVACIGLLTDERLVTAEAQSPGNKLVLVGNATGRDGLGGASFASEDLSEDAETEDRPAVQVGDPYTEKRLIEANEELITAELIQSARDLGAAGLGGASSELVAKGGLGARINLERVHQREPAMNAMEILLAESQERMCYEVHPDDVETVGDIAAKYDLGYAVIGEIRDGNYVCTFGDETVVDVPAGFLADGAPMNDLSATEPPTPEESTFPAIDAATAFNTIISTPNTASKRWIYRQYDHEVGLRTAMRPGDDAALIAIREAGVGLALSSGAVPAWTESNPYKGAQAVALENATNVAAKGATPIAAVDCLNGGNPEKPAVYGAFKDIVQGLADMCHTLSIPVVGGNVSLYNDSTSGPIPPTPTLALVGTKKTFDAPPAALTGDGTLLLVGHQSNNLGGSELLAQIGGTDKFPALPSNPTAVVDSLARVANHPSTLATHDVSTGGLAVTLAELITSDAGARVTVQNKTSLFTETPGRAVIETTDPDAVRHIFEGVAPVVSLGDTTTDGTLTINIDDEDTANESPAVTTDAATVAKQRRILEDALE",
    "output": "Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "AEQLQRLKAEFQANRYITEQRRQSLAQELSLNESQIKIWFQNKRAKIKKASGMKNGLALH",
    "output": "Required for proper formation of the apical ectodermal ridge and correct dorsal-ventral patterning in the limb."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MLERIKGCFTESIQTQIAAAEALPDAISCAAMALVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNADNVVLTAITNDRLHDEVYAKQVRALGQAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGQLDVEIRIPSHRGARVQELHMLTVNCLCDLIDNTLFPHQDD",
    "output": "Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDRLRIVGGRRLEGAVTISGAKNAALPQIAAALLSPYPLELTNLPDVTDVENMLGVVRLHGAEVTRSAHAATIDTSAAVSKETSYDTVRKMRATVLVLAPLLARFGHARVSLPGGCAIGARPVDMHVAALAALGAKIAIENGLIVASAPNGLTGTRIVLSSPSVGATETAMMAATTAKGETEILNAAREPEVADLAACLNAMGARIEGAGTHRILIAGDTGWHAARHDIIPDRIEAGTYAIAAAITGGQLELTHARLEHMASVVQLLEATGVSVWPGDRGLIVSRERPLKAADLTTEPYPGFPTDLQAQFMALMCCAEGASLLRETIFENRFMHVPELMRLGANIKLQGTMALVRGGEKLHGAQVMATDLRASVSLVLAALVSEGETIINRVYHLDRGYEQLDRKLRLCGADIERLSA",
    "output": "Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKLLVKAPAKINLSLDVLGKRQDGYHEVKMIMTTIDLADRLELTELAEDRIEILSHNRYVPDDQRNLAYQAAKLLKEKFNVKKGVSITIEKTIPVAAGLAGGSSDAAATLRGLNKLWNLGLTIDELAELGAEIGSDVSFCVYGGTAIATGRGEKIEHIKTPPSCWVILAKPHIGVSTADVYGNLKLNRVTHPNVDKMVDVINSGDYKGICDTVGNVLEDVTFGMHPEVARIKSQMKRFGADAVLMSGSGPTVFGLVHHDSRMHRIYNGLKGFCEQVYAVRLLGERETLE",
    "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MATPWRRALLMILASQVVTLVKCLEDDDVPEEWLLLHVVQGQIGAGNYSYLRLNHEGKIILRMQSLRGDADLYVSDSTPHPSFDDYELQSVTCGQDVVSIPAHFQRPVGIGIYGHPSHHESDFEMRVYYDRTVDQYPFGEAAYFTDPTGASQQQAYAPEEAAQEEESVLWTILISILKLVLEILF",
    "output": "May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEQRNNVFQAKYNEYKQILEELQTKIIELGHDKDEHTIVIKTLKDAEPTRKCYRMIGGALVESDVQTSLPILETKKENIEGTISKMKETLIQTAKEFEKWKKDNKIQVVKN",
    "output": "Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRFQGFWLCLGLLFISVNAEFMDDSVEMEDFDENSEETDELSSEIKYKTPQPVGEVYFTETFDSGRLAGWVLSKAKKDDIDAEISIYDGRWEIEELKENRIPGDRGLVLKSRAKHHAISAVLAKPFIFADKPLVVQYEVNFQDGIDCGGAYIKLLADTDGLNLENFYDKTSYTIMFGPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKRFFTDRKTHLYTLVMNPDDTFEVLIDQIVVNKGSLLEDVVPPINPPKEIEDPTDEKPDDWDERAKIPDASAVKPEDWDESEPPQIVDSSAVKPDGWLDNEPEFIPDPNAEKPFDWNEDMDGEWEAPHISNPACRIGCGEWSPPMIDNPKYKGIWRPPMIDNPNYQGIWSPRKIPNPDYFEDNHPFLLTSFRALGLELWSMTSDIYFDNFIICSEKEVADRWAADGWGMKILIENANEPSIFKQLMSATEQRPWLWFIYLLTAALPIALIGSFCWPRKVKKKYEDVAFEKLDICKPQTKGALEQEVKEEKAALEKPVDLEEEKKQSDGEIVEKEEEGEPEEKSEEEIEIIEGQEEGNKSNKSGSEDEMKEADESTGSGDGPIKSVRKRRVRKE",
    "output": "Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAAAAVGGRGERLSSSSPTAAAPQVDAGKYVRYTPEQVEALERVYTECPKPSSLRRQQLIRECPILSNIEPKQIKVWFQNRRCREKQRKEASRLQTVNRKLNAMNKLLMEENDRLQKQVSRLVYENGYMRTQLHNPSAATTDTSCESVVTSGQHHQQQNPAVLHPQRDANNPAGLLAIAEETLAEFMSKATGTAVEWVQMVGMKPGPDSIGIIAVSHNCSGVAARACGLVSLEPTKVAEILKDRPSWYRDCRCVDIIHVIPTGNGGTIELIYMQTYAPTTLAAPRDFWTLRYTSGLEDGSLVICERSLTQSTGGPSGPNTPNFIRAEVLPSGYLIRPCEGGGSMIYIVDHVDLDAWSVPEVLRPLYESPKILAQKMTIAALRHIRQIAHESSGEIPYGAGRQPAVFRTFSQRLSRGFNDAVSGFPDDGWSLLSSDGSEDITISVNSSPNKLVGSHVSPNPLFSTVGGGILCAKASMLLQNVPPALLVRFLREHRSEWADPGVDAYSAASLRASPYAVPGLRTSGFMGSQVILPLAHTLEHEEFLEVIRLEGHGFSHDEVLLSRDMYLLQLCSGVDENATSASAQLVFAPIDESFADDAPLLPSGFRVIPLDTKMDGPSATRTLDLASALEVGPGGASRASVEASGTCNRSVLTIAFQFSYENHLRESVAAMARSYVRAVMASVQRVAVAIAPSRLGPQIGMKHPPASPEALTLASWIGRSYRAHTGADIRWSDTEDADSPLALLWKHSDAILCCSLKPAPMFTFANNAGLDILETTLVNLQDISLEMILDDEGRKALCSEFPKIMQQGFTYLPGGVCKSSMGRQASYEQAVAWKVLSDDDAPHCLAFMLVNWTFM",
    "output": "Probable transcription factor."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAAAPARGGGGGGGGGGGCSGSGSSASRGFYFNTVLSLARSLAVQRPASLEKVQKLLCMCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDCVVPYLLRLLKGLPKVYWVEESTARKGRGALPVAESFSFCLVTLLSDVAYRDPSLRDEILEVLLQVLHVLLGMCQALEIQDKEYLCKYAIPCLIGISRAFGRYSNMEESLLSKLFPKIPPHSLRVLEELEGVRRRSFNDFRSILPSNLLTVCQEGTLKRKTSSVSSISQVSPERGMPPPSSPGGSAFHYFEASCLPDGTALEPEYYFSTISSSFSVSPLFNGVTYKEFNIPLEMLRELLNLVKKIVEEAVLKSLDAIVASVMEANPSADLYYTSFSDPLYLTMFKMLRDTLYYMKDLPTSFVKEIHDFVLEQFNTSQGELQKILHDADRIHNELSPLKLRCQANAACVDLMVWAVKDEQGAENLCIKLSEKLQSKTSSKVIIAHLPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVIPSPVLVKLYKYHSQYHTVAGNDIKISVTNEHSESTLNVMSGKKSQPSMYEQLRDIAIDNICRCLKAGLTVDPVIVEAFLASLSNRLYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIIDQLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAANIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTRRLPPIKEAKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSKEPLRSVLQYNSAMKNDTVTPAELSELRSTIINLLDPPPEVSALINKLDFAMSTYLLSVYRLEYMRVLRSTDPDRFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMADKAKTKENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLSADIHKDQPYYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGATQLSERPACVKKDYSNFMASLNLRNRYAGEVYGMIRFSGTTGQMSDLNKMMVQDLHSALDRSHPQHYTQAMFKLTAMLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKDGVEVPFMREMAGAWHMTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNLDITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSRTYDMIQYYQNDIPY",
    "output": "Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRNSIFEQEETFQDLSLRPKSIEKFVGQQRVVENLQVFIDSAQKRNDSLDHVLFCGPPGLGKTTLAHIISNELESRIHTTAGPLLSKAGDIAAILTNLHKNDILFIDEIHRLPSAVEEVLYPAMEDYHLDLIVGDGPAAKSIRINLAKFTLVAATTRIGMLSNPLRDRFGITLRLDFYTVSELLQLLQQAAERLSVNIENGAMIELAKRSRGTPRIALRLLKRVRDFLEVSDSDVITREFADLALNKMEVDQFGLDKLDYTYMDFIAKNYSDNPVGIKTIAAAISEKEDSIEELIEPYLIKIGFLSRTQRGRRLTGKALDYLSTINSARLP",
    "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNLNLAGADAGTVEVSDATFGKEFNESLVHQVVTAYFAAGRQGTRAQKTRSEVRGGGKKPWRQKGTGRARAGTIRSPLWRSGGVTFAARPQDYTQKVNRKMYRAAMRSILSELVRQERLVVVDSFEVDAPKTKQLVAKLKDLDLEKALIVTEDIDEKLFLAARNIPYVDVVDVAAADPVSLVAFDKVLVTVSALRKFEEKLG",
    "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQLVERFLCEPFPPLAQRIIQEGVVVNDRILKIDHFLNHRIDTDLMSAIGVELATRLQPFAAELILTAEASGIPPALATALAARLPLVYAKKYDPDVPVPALTRHIHSPTRDRQVQLAISARFIPAGSRVAIVDDFLANGRTALALADMVYEAGATVVAAAFVVEKQFQEGRLLLQKLGVPIISLAQITRFVDGRPLIYGWPSSVPGQSDG",
    "output": "Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MKLHIVAVGHKMPGWIASGFDEYAKRMPPELRIELREVKPELRSGSRTADSVMAAEQQRIEAALPKNARVVALDERGRDWTTMQLAQALPAWQQDGRDVAFVIGGADGLAPALKSRAELLLRVSSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA",
    "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKQLLFNEEARKSLLAGVEQISNAVKVTLGPKGRNVLIDKSFGAPTVTKDGVSVAREVELENKFENMGAQLLKEVATKTNDVAGDGTTTATVLAYSMVKEGLKAVAAGMTPLELKRGIDKAVAIAVEDIQKNSKEIKGSEEVAHVASVSANNDAEIGKIIADAIAKVGKDGVIDVGEAQTMETVTDYVEGMQFDRGYISSYFVTDRDRMETVFENPYILIYDKSISTMKDLLPLLEQVAQSGRPLLIIAEDVEGEALATLVVNSLRGALKTCAVKAPGFGDRRKEMLEDIAVLTGGQVVSEELGFKLEAAQISMLGQAKSIKIDKDNTMIIDGAGKSKDIKDRVTQIKAQLDATDSEYDSEKLRERLAKLSGGVAVIKIGAVTEVEMKEKKHRVEDALSATRAAIEEGIVAGGGLAMIQAIAALEKADMSSLTEDEKVGFKIVKRALEEPIRQIAENAGLDGAVIAEKAKEKKGVGFDAAKMEWTDMVKAGIIDPAKVTRSALQNAASIASLLLTTECAITDIPEKQAGPAMPSPDMGGMGMY",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTQSNPNEQSVELNRTSLYWGLLLIFVLAVLFSNYFFN",
    "output": "One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMTTLRRRLPDIVQYSVLSLAAFLSIFPFIWMVIGTTNTTSQIIRGKVTFGTALFDNIASFFAQVDVPLVFWNSVKIALVGTALTLLVSSLAGYGFEMFRSKLRERVYTVILLTLMVPFAALMIPLFMLMGQAGLLNTHIAIMLPMIASAFIIFYFRQASKAFPTELRDAAKVDGLKEWQIFFYIYVPVMRSTYAAAFVIVFMLNWNNYLWPLIVLQSNDTKTITLVVSSLASAYSPEYGTVMIGTILATLPTLLVFFAMQRQFVQGMLGSVK",
    "output": "Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEHADQYSWIIPFVPLPIPILIGMGLLLFPTATKRLLLFPTATKNLRRMWAFPNILLLSIVMIFSLDLSIQQINGSSIYQYVWSWTINNDFSFEFGYFIDSLTSIMSILITTVGIFVLIYSDNYMSHDEGYLRFFAYMSLFNTSMLGLVTSCNLIQIYIFWELVGMCSYLLIGFWFTRPAAANACQKAFVTNRIGDFGLLLGILGFYWITGSFEFQDLFEIFNNLIYNNEVHFLFVTLCASLLFAGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLFPLFIVIPYIMNLISLIGIITVLLGATLALAQNDIKRGLAYSTMSQLGYMMLALGMGSYRAALFHLITHAYSKALLFLASGSIIHSMEAIVGYSPEKSQNMVFMGGLRKHVPVTQIAFLVGTLSLCGIPPLACFWSKDEILSDSWLYSPIFAIIAWSTAGLTAFYMFRIYLLTFEGHLNVHFQKYSGKKSSSFYSIKLWGKEEQKIINRNFRLFPLLTLTMNNNEQPYTIGGKKEARITITNFGYKKAFSYPHESDNTMLFPMLILLLFTLFVGAIAIPFNQEGMHLDILSKLLTPSINLLHQNSNDFEDSYQFFKNATFSVSIACFGIFTAFLLYKPFYSSVQNLNLLNSFVKRGPKRILLDKMIYLIYDWSYNRGYIDMFYSISLTKGIRGLAELTHFFDRRVIDGITNGVGITSFFVGESVKYLGGSRISFYLLLYLVYVFIFLVISYFILF",
    "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSQNKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDTEPYSVHLAGELKNFNIEDHIDKKEARRMDRFTQYAIVAAREAVKDAQLDINENTADRIGVWIGSGIGGMETFEIAHKQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGATVTACATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGAGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPKDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATGGIEAIFSALSIKDSKVAPTIHAVTPDPECDLDIVPNEAQDLDITYAMSNSLGFGGHNAVLVFKKFEA",
    "output": "Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAKIIGIDLGTSNSAAAVMEGGKTTLIPSAEGTTLGGKAFPSYVAFTKDGQLLVGEPARRQAVTNPEGTINAFKRKMGTNYKYKVNGKEFTPQQLSAFILQKIKKDSEAYLGETITKAVITVPAYFNDDQRQATKDAGAIAGLEVVRLVNEPTAASLAYGIDKVGKEQKILVFDLGGGTLDVTIMEMGAEGTFEVLSTSGDTQLGGTDMDNALIDYIAEDFKKTNGIDLRNDKMAVQRLKEAAEKAKIELSNVLETDINLPFITADASGPKHLAMKFTRATLENLVRHIVERCKASIDQAVKDAKLTAETVTKIILVGGPTRMPIVQKFAEDHVGKKAERGIDPMECVCFGAAVQAAVLTGDVKDILLLDVTPLTLGLETMGGVRTSLIDRNTTVPAKRSQVFSTAADNQPSVEINVLQGERAMAKDNLSLGRFMLDGIPPAPRGVPQIEVTFDIDANGILHVSAKDKGTGKEQSIKISSSTKLSKDDIDKYVKEAEQYASEDVKRKEEIEVRNEADNLIYSVEKSLKDHGDKVSADERLIIEQSLTAAKDALKGSDVATIKSAKEALTTASHKLAEVVYKASQVQDTQGAAQGQSQGNPQQTADNRGKVVDAEIVDENKE",
    "output": "Acts as a chaperone."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAATKWRDIDDLPKIPANYTALTPLWFLDRAAVVHPTRKSVIHGSREYTWRQTYDRCRRLASALADRSIGPGSTVAIIAPNIPAMYEAHFGVPMCGAVLNCVNIRLNAPTVAFLLSHSQSSVIMVDQEFFTLAEDSLRLMEEKAGSSFKRPLLIVIGDHTCAPESLNRALSKGAIEYEDFLATGDPNYPWQPPADEWQSIALGYTSGTTASPKGVVLHHRGAYIMALSNPLIWGMQDGAVYLWTLPMFHCNGWCFPWSLAVLSGTSICLRQVTAKEVYSMIAKYKVTHFCAAPVVLNAIVNAPKEDTILPLPHTVHVMTAGAAPPPSVLFSMNQKGFRVAHTYGLSETYGPSTVCAWKPEWDSLPPETQAKLNARQGVRYTGMEQLDVIDTQTGKPVPADGKTAGEIVFRGNMVMKGYLKNPEANKETFAGGWFHSGDIAVKHPDNYIEIKDRSKDVIISGGENISSVEVENVVYHHPAVLEASVVARPDERWQESPCAFVTLKSDYEKHDQNKLAQDIMKFCREKLPAYWVPKSVVFGPLPKTATGKIQKHILRTKAKEMGPVPRSRL",
    "output": "Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle. May play a role to prevent carbon loss from peroxisomes during lipid mobilization. In vitro, is active with both acetate and butyrate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSTAAARPGRRFTVGRSEDATHPDTIRAAISEFLATAIFVFAAEGSILSLGKLYQDMSTPGGLVAVSLAHALALAVAVAVAVNISGGHVNPAITFGALLGGRLSLIRALFYWLAQLLGAVVATLLLRLTTGGMRPPGFALASGVGDWHAVLLEATMTFGLMYAYYATVIDPKRGHVGTIAPLAVGFLLGANMLAGGPFDGAGMNPARVFGPALVGWRWRHHWVYWLGPFVGAGLAGLLYEYLVIPSADAAPHGGAHQPLAPEDY",
    "output": "Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. May be involved in transport from the vacuolar compartment to the cytoplasm (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKKNVHPKYNEISAYCSCGNIINTKSTLNRNLNIDVCHLCHPFYTGTQRILDTRGRVNIFNKRFNLSINADFLPIDKKLNKK",
    "output": "Binds the 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTQENIPVQPGTLDGERGLPTVNENGSGRTRKVLLFLFVVGFIVVLLLLLVFHMRGNAENNHHSDKTMVQTSTVPMRTFKLPPPPPPAPPEPPAPPPAPAMPIAEPAAAALSLPPLPDDTPAKDDVLDKSASALMVVTKSSGDTNAQTAGDTVVQTTNARIQALLDSQKNTKQDAGSLGTLLHGTQTDARMASLLRNRDFLLAKGSIINCALQTRLDSTVPGMAACVVTRNMYSDNGKVLLIERGSTISGEYDANVKQGMARIYVLWTRVKTPNGVVIDLDSPGADPLGGAGLPGYIDSHFWKRFGGALMLSTIETLGRYATQKVGGGGSNQINLNTGGGESTSNLASTALKDTINIPPTLYKNQGEEIGIYIARDLDFSSVYDVKPK",
    "output": "The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. Virb10 seems to be per se essential for intracellular multiplication within non-professional phagocytes and is essential for pathogenesis in mice."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELFERKLEMHQGHLLKSAVELAKDWRTDRALRKLEAMLIVADEKESLIITGIGDVVQPEEDQILAIGSGGNYALSAARALVENTELSAREIVEKSLKIAGDVCVFTNTNFTIEELPN",
    "output": "Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLEFEQGFNHLATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESKIQIGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVTSGMGGGTGTGAAPVVAKIAKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDTLIVIPNDRLLDIVDKSTPMMEAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIMSNQGSALMGIGVSSGENRAVEAAKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINPELQDEIVVTVIATGFDDKPTSHGRKSGSTGFGTSVNTSSNATSKDESFTSNSSNAQATDSVSERTHTTKEDDIPSFIRNREERRSRRTRR",
    "output": "Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARMIHCAKLGKEAEGLDFPPLPGELGKRLYESVSKQAWQDWLKQQTMLINENRLNMADPRARQYLMKQTEKYFFGEGADQASGYVPPAQG",
    "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNIEKHLISLINDLCQISGVEVGQHFYWQLGGFQVHAQVLITSWVVIVLLSGLAFVTTRDLRTIPTGGQNFVEYVLEFIRDLTRTQIGEEEYRPWVPFIGTLFLFIFVSNWSGALFPWKIIQLPHGELAAPTNDINTTVALALLTSVAYFYAGLHKKGLSYFGRYIKPTPILLPINILEDFTKPLSLSFRLFGNILADELVVAVLISLVPLVVPIPMMFLGLFTSAIQALIFATLAAAYIGESMEGHH",
    "output": "Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "GNVAELTEVR",
    "output": "Has antimicrobial activity against L.paracasei BGKP20."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRPNNRELNQVRPVKITRHYTRYAEGSVLVEFGETKVLCNATVEETVPRFLKGQQQGWVTAEYGMLPRSTHSRMQREAAKGKQGGRTMEIQRLIARSLRAVVDLKALGERTVTVDCDVIQADGGTRTAAITGACVALHDAMSKLVADGVLKENPMKGLVAAISVGIVDGNAVCDLEYVEDSNAETDMNVVMVEDGRLVEVQGTAEGEPFSHMELLQLLDLAHQGINQLLDAQRKALAL",
    "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELAENNPLDDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKHWQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAVADDLASLVLDARMEQEGYARSSINPFLFPGEGE",
    "output": "Necessary for formate dehydrogenase activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEGGSASGSASALSNDENLVVSCEDSSSPIGNELELGLTLSLGRKGYRDCRVYADDSSSSSSSSSLSRASVIAGIKRTADSMAATSGQVVGWPPIRTYRMNSMVNQAKASATEDPNLEISQAVNKNRSDSTKMRNSMFVKVTMDGIPIGRKIDLNAHKCYESLSNTLEEMFLKPKLGSRTLETDGHMETPVKILPDGSSGLVLTYEDKEGDWMLVGDVPWGMFIGSVRRLRIMKTSEATGKAQMIL",
    "output": "Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNYKDIINACILSGVFLLHSPSALADTPSVGVSKGQESLQPAAEGNLWQRLIRNVSLAWNSPHQELYIPVNTWHNRWTYDDEKIASYNERPWGVGYGKYRYDEDNNWHSVYAMAFMDSHNRVEPILGYGYQKMWIPGEREGWRFGAGFTASITARYEYHYIPLPLPLPLISIEYNRLSLQTTYIPGTYNNGNVLFTWIRWQF",
    "output": "Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVEESELKYFVRIINTDLDGTQPVQLALTGIKGIGLHAALIIARRAGVDTRATMGLLGDEDVAAIEEQVKAYPASVPKWMVNRPVDVYSGEPKHLYGSDLSLAKEDDINLMKKMRCYRGIRHENGLKVRGQRTKATGRFGKIVGVSKRRN",
    "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSLYIGLMSGTSMDGIDAALLELPSNQLIHGITKQYSDDVRRNLDDLIIGNHLTLASICQLNTLIGREFAEAVRQLLIEIKVHPKEIQAIGSHGQTVCHDTSGNIPYTLQLGCGHTISSLTGITVVADFRTRDLVNGGQGAPFAPLYHQQIFSKVNESVAVVNIGGIANVTFIAKNQMTRGWDIGPGNCLMDAWIYKNKGALFDKNGVWASQGEVIHPLLEYLLQDPFFHLDSPKSIGKEYFSLSWLQKHLKPDYTPADIQATLLALTAHTIAETILNESGEIKQLYLCGGGAHNTHLKESLARLLPGITVKSIAELGISPDYLEAMMFAWLAAQTINQIPVNLASITGAKGIAILGAVYPIIKSY",
    "output": "Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSLIDQAKEQMAKTVENTKENFSGIRTGRANPALLNGITVDYYGAPTPIKAVASIGVPEPRTLSVTPFDASQAGAVEKALRNSDLGISPNRDGNVIRLTMPELTEDRRKEYVKLAKGKAEDGKVAVRNIRRKTKETIDKAVKDGEMGEDEGDRLLKDLDKVTKSVTDEIDTLLETKQKEIMEV",
    "output": "Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRRYRIDSMKYEQRMNAGASGFDMSDWNNPYNASPPSSRGGDDDASSVNHSRPRRSRLDNDIPQPRRPILIQPARPVSQKSNRQGTGMSNGSRGLNSTFNGYDRTYSRYHQNSSRGPSEGFSGAPSARNASGYASDYANSRAGVGLLPNNHREPVRPRSTAAERYANASSMRNGFVYDSGESDKTSEELEEDEEEEEVRNFYMEGRAQGSRSVTNTLASEVYNSESESYYYGVVKLGSAIVDHVFRTMPPPEKYYKMPPIDRVAYVFYCAVNNKPYNNIDEFHVIFNREFYSYRGYGDSKDLALFKVCKRMQEEFSLKQLEADRLAYEKARQEAAESEKLDFNQHKIEEREEPKLNISQPEEVLSNGPLHYHSCLQFATIGVGGKLVIIKPAGTIDSITGHVLSTSSVHVDDLKTFLHFDEQSGKVIESVQNFKGPLIAGQTPTHSVRLYIQRQIDALRQIRNAGDVKKSEVVDALLVWQLLEIMVQQHGRVTGPDVATLLTNASEELGEKTGISSNGTSESGSKFEAKERFNKYLLGGHINEAVESAITDGLYADAMTLIRRLHPNDAKKIEEIEARFMNLRSIDDPFATLVAVSSDQPPPILTNSAFDDDNNWKRHAAIVLANLNSQTAMQTIYHLGLLLAKRERNCAADFCLLVVCILAGYDPFIPVAHDGDETSRKHIGLVHSGSNLLNRVDGLSGTAGFSFTDLHATDIFDYALRLGNNNVDSPLAKSIDYQLARIEYAKKLSSFGGFATDAFRYCTEVARSLWMYVAAFDKNAMFDLCDLAESLQYMAAATPDESGWITTMRGMLGAAPVQESQQHVPQPQPVENKSISSEAKKWHDEHQAPLEIGSRNDQQHNDKTVEKPIAPGRASLPPPTLVTESSSESTFTDKSDSSVTVAASASRTSTLTSSTLPPPPSLPKTIEKPISTPPPISKNVVPEMTPPAIVKPPMPTLSMPIPPVSTPIMVSPQPIPIPKPVDASIAKSPRSELDDLWDTSPPSNQTSYPPAPRNIQPSYSPAPNFANPTAPSVPTPPPAVSSAPVLQQATLGQASIPNAKTTAPPVPQKQPELALNERKASKGWFGSIKEKVIKSIPSANQMILPDDSKPSIVWDPVQKRYVGAGVEEEVVAAPPPVMSAPHLMGGGPDSNKSSTNSLRSARSGVGSRYLQSGMATSQAPAMDTGMPPMMPPTMPMSFSFMPAPTEDDSSEYVDPFSGEPTAPSESLSKQNND",
    "output": "Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) . In association with tfg-1, accumulates at ERES to positively regulate secretory cargo trafficking from the endoplasmic reticulum to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) and Golgi apparatus ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAAKRKAAAMNAVDDEPVDPSDELAFYCLGGGNEVGRSCHIIQYKGKTVMLDAGMHPAKEGFSALPFFDEFDLSTVDILLISHFHVDHSSALPYVLSKTNFKGRVFMTHATKAIYKWLIQDNVRVNNTASSSDQRTTLYTEHDHLSTLPLIETIDFNTTHTINSIRITPYPAGHVLGAAMFLISIAGLNILFTGDYSREEDRHLIPATVPRGVKIDVLITESTFGISSNPPRLEREAALMKSITGVLNRGGRVLMPVFALGRAQELLLILEEYWETHPELQKIPIYYIGNTARRCMVVYQTYIGAMNDNIKRLFRQRMAEAEASGDKSVSAGPWDFKYVRSLRSLERFDDVGGCVMLASPGMLQTGTSRELLERWAPNERNGVVMTGYSVEGTMAKQLLNEPDQIHAVMSRAATGMGRTRMNGNDEEQKIMIPRRCTVDEISFAAHVDGVENRNFIEEVSAPVVILVHGEKHQMMRLKSKLLSLNAEKTVKVKVYTPANCEEVRIPFRKDKIAKVVGKLAQTTLPTDNEDGDGPLMAGVLVQNGFDLSLMAPDDLREYAGLATTTITCKQHITLSSASMDLIKWALEGTFGAIEEIGTDEDAEKEDQQSESEEKQRMKEEADEEIPMEKPQAYLVMGCVVIRYHPRTREVELQWEGNMMNDGIADAVMAVLLTVESSPASVKQSAKHNKHHHHHHHDETDTLKFLNPHAAQDAEERFARLLMMLEAQFGSDIAPIERPRVPSSTESATTTTNGNGNSKSDSEQLSSLESKTDGATPQDPDTLSELEAAELSRLHALGIPVPGIEIKVDKHVARVWLEDLEVECANAVLRDRVRVVIERAVETVASMWSVGRSSKTITNGGGKEIAGTGADDVASKPGLEVAARA",
    "output": "Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSVMDALFLLATEEVGHFGINTNLLETNVINLAILIGVLVYFGRGVLGKTLGDRQKQIATAIAEAEERQKVAAARLAEAQQKLTQAKQEAQRIREDALTRAKAVKEEIIAQAKREIERLQETASQDTSAATERAIAEIRERIAAMALAEAENQLKARLSQNPDLQRTLIDRSIALLGGK",
    "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "KHGSINCRLPPERGPCRGNITKYYYHNESRTCRTFSYGGCEGNSNNFRNRHYCMKYCARKRHGWLGTGWI",
    "output": "Dual-function toxin that inhibits 85% of the activity of trypsin at a molar ratio of 4:1 with a dissociation constant of 760 nM, and that inhibits mKv1.3/KCNA3 potassium channel currents, but very weakly."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MESPHLSVLKNEVLEIFAPLSEGYFIDCTLGFGGHSEAILKAHPKLSLIGIDQDPHALEFSQKRLAPFKDRFSFREGRFSEVLPTLKELPIAGILADIGVSSLQLDDSSRGFSFHSERLDMRMNPNAQLSALEVVNSYPQDRLERIFKEYGEIKESKKLVSLISEERKKGRITSAEALSRLIERHFKRVGNIHPATLAFQAIRIEVNDELGEIGRALQTIGEIAKGRVSIISFHSLEDRLVKNFFKEWSNSCLCPPEAFRCTCGNNHEKGQILTKKPLVATPEESKANPRSRSAKMRAFEFKS",
    "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSRIGKRPIALPAKVEVQIEGQQISVKGPKGELSRSLPPLIAVHQEAQTLKVSRVNESRPARQLHGLCRTLVANMVDGVSRGFERRLELVGVGYRASTQGNKLILNVGYSHPVEIPFPPGIQIAVEGNNVIVVSGIDKELVGNTAARIRAVRPPEPYKGKGIRYVGEQVRRKAGKSGKAKK",
    "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MADPKGSTSKDGLDDWCIVEAECSDIENDLEELFDRDTDSDISELLDDNDDLDQGNSRELFHQQESKESEEHLQKLKRKYLSPQAIAQLSPRLESITLSPQQKSKRRLFAEQDSGLELTLTNEAEDVSSEVEVPALDSQPVAEAQIGTVDIHYTELLRASNNKAILMAKFKEAFGVGFNDLTRQFKSYKTCCNHWVLSVYAVHDDLLESSKKLLQQHCDYVWIRGIAAMSLFLLCFKVGKNRGTVHKLMTSMLNVHEKQILSEPPKLRNVAAALFWYKGAMGSGTFTYGPYPDWMAHQTIVGHQSTEANAFDMSVMVQWAFDNNYLDEADIAYQYAKLAPEDSNAVAWLAHNNQARFVRECASMVRFYKKGQMKEMSMSEWIHTRITEVEGEGHWSTIAKFLRYQQVNFIMFLAALKDMLHSVPKRNCILIYGPPNTGKSAFTMSLIRVLRGRVLSFVNSKSQFWLQPMSECKIALIDDVTDPCWLYMDTYLRNGLDGHYVSLDCKHKAPIQTKFPALLLTSNINVHNEITYRYLHSRIKGFEFPNPFPMKADNTPEFELTDQSWKSFFTRLWNQLELSDQEDEGDNGESQRPFQCSARSANEHL",
    "output": "ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins. During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity. Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer. Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori. Subsequently, two hexamers will be created. The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGLFITFEGGEGAGKSTQIALLASHLRNHGFDPVITREPGGSPGAEAIRHVILSGNAETYGPAMEALLFAAARADHVDQLIRPALAEGRIVLCDRFIDSSRAYQGVTGNLDATYMAAIERIAIDGAMPDLTLVLDICAERGLSRAGKRRGSDTADRFEKEDIAVHEARRQAFLEIARQEPARCKVIDADRSQEKIADEIRSVVDTILTEKGLL",
    "output": "Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATYSSNDFRAGLKIMMDGEPYAVESSEFVKPGKGQAFARVKLRRLLTGSRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLAADAKAVGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK",
    "output": "Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MADPSLNNPVVIQATRLDASILPRNVFSKSYLLYVIAQGTDVGAIAGKANEAGQGAYDAQVKNDEQDVELADHEARIKQLRIDVDDHESRITANTKAITALNVRVTTAEGEIASLQTNVSALDGRVTTAENNISALQADYVSKTATTSQSLASPLNVTTSYSVGGKKVLGARQTGWTAATGTANKGVFDADLTFAVSDTYTQSEIQAIANALITERRRTKALEDALRAHGLID",
    "output": "Cell-perforating component and plug protein of the phage tail machine . Together with gp4 and gp10, gp26 is required for stabilization of the condensed DNA within the capsid by plugging the hole through which the DNA enters . Host cell membrane perforation allows viral DNA ejection . The needle penetrates the host outer membrane. The needle is released and the internal head protein gp7 is ejected to form an extra-cellular channel ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIMSLSILYILPEILLALGVIVVMFSGLFLHGKIRNINYIFFQVFTLLALIATFAKEYLIQTTGLVFEGQVVFSGFAYTLQLVILVLAVFVALYSRDYVKDRKISDGDFYTLLMLCVLGAMVLTAAHSLVTIYVGLELLSLPMYALIAIYRDSGKGLEAAIKYFVLGAIASALLLFGMSFVYGMTGKLDITEIANVLAHGNFAGLQQQFLLVYLVMMIATFLFKLGAFPFHMWLPDVYQGAPNAVANIVATIPKVAAFAMLVNILFVGFPSLKDSWIYLFRIIGILSIFFGSLVALSQTNVKRLLGYSTVSQIGFVLLATTLNPQGYALTAASFYVIVYLFTTLAVFGVLTTISVGGYEVQDLNDLKGFNTKDSWLAFILLIVLFSMAGIPPFGGFIAKLFVVMGLINDGNYFLACFVLFMAVIASFYYVRVIKTMYFDDPDNDETVKPPLTSLIALSINGLVLLFLGIMPMLLLGVLTQVTNVI",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQVLVNKIWYEGHPLRWLLLPFSVLFALITAIRRSLFRLGLKSQTPLPVPVIVVGNITVGGSGKTPTVIYLIELLRQQGFNPGVISRGYGADIQGVKVVTAADSAASVGDEPAMIVARTGVPMVVGAKRVDTAKALLAQFAVDVIICDDGLQHYALGRDIELVVIDGKRGLGNRHLLPAGPLREGAWRLNQVDFVVVNGGPAQANQYEMQLSPSAVLPVNPKAVAVFDPTQPVVAMAGIGHPARFFETLTQQGFQLALSHGFDDHQAYDKEVLCELAASRPLMMTEKDAVKCRDFAQENWWYLAVDAKLSPQFDQQLLSRVRSVAAAKQGKSHGV",
    "output": "Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDTLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLAMVYLGTKGTTAAQMGQVLQFNRDQGVKSSPESEKKRKMEFNSSNSEEIHSDFHTLISEILKPNDDYLLKTANAIYGEKTYPFHNKYLEDMKTYFGAEPQSVNFVEASDQIRKEINSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLQIFHIEKPQAVGLQLYYKSRDLSLLILLPEDINGLVQLEKDITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGTGSEIESRIRVPSIEFNANHPFLFFIRHNKTNSILFYGRLCSP",
    "output": "Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSSLVTPQHAEELSTGARQLGVELSAQQHELLLGYLALLIKWNKAYNLTAVRDPDEMVSRHLLDSLSVMPFIHNDTQRWLDVGSGGGMPGIPLAILHPHKQVTVLDSNGKKTRFLTQVKMELKLDNLTVIHSRVEEVQPEQPFCGIISRAFSSMENFTNWTRHLGDSRTQWLAMKGLHPADELVALPADFTVESEQALTVPGCQGQRHLLILRRKA",
    "output": "Specifically methylates the N7 position of guanine in position 527 of 16S rRNA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEEIVVHGGQRLTGNVHIEGAKNAVLPILAASLLASSGQTHLSNVPVLSDVFTMNNVLKFLNTKIDFDEINKTIDIDASRQLSSEAPFQYVSKMRASIVVMGPLLARLGHAKVAMPGGCAIGSRPIDLHLKGLNALGAEIERHDGYVEATANQLHGAAIYLDFPSVGATQNIMMAATLADGITTMENVAREPEIVDLANYLNQMGAKVTGAGTETIRIEGVKAMHGCDHSIVQDRIEAGTFMVAAAVTQGNVLVEDAIAEHNKPLISKMREMGVTVTEEPAGIRVIGPEILKPTSVKTMPHPGFPTDMQPQMTILQLCAQGTSLLTETVFENRFMHLDELRRMNADFKVEGRSVIMYGPTDFNGAQVTATDLRAAAALVIAGLVSRGYTEVTNLKYLDRGYFNFHGKLAKLGAEIKRVDVPDGTVYALNPDFANEAAE",
    "output": "Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAEYTLPDLDYDYGALEPHISGQINELHHSKHHATYVKGVNDAIAKLEEARANGDHAAIFLNEKNLAFHLGGHINHSIWWKNLSPNGGDKPTGELAAAIDDQFGSFDKFQAQFTAAANGLQGSGWAVLGYDSLGGRLLTFQLYDQQANVPLGIIPLLQVDMWEHAFYLQYKNVKADYVKAFWNVVNWDDVQNRFAAATSKTSGLIFG",
    "output": "Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKAYWYDNIPGDQRLPHDSGRTVDASYLATIGVLYRHCPAISAVDDLARDRGYKNRDEIIISPEKMGDVYEDKVRMFFNEHLHEDEEIRYIVDGEGFFDVRSKDDEWVRIRLGKGDLIVLPAGIYHRFTTDENNYVKAMRLFQDEPKWTPLNRAPELDANQHRKTYVESHISSSTA",
    "output": "Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKQIFIGIIRFYQKFISPMTPPTCRFYPTCSHYGLEAFQKHGALKGFWLTCKRILKCHPFHPGGFDPVPDKKDDKVNS",
    "output": "Could be involved in insertion of integral membrane proteins into the membrane."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSTLEENYQYCHQIMKDYSKSFSYAFDMLPEQQRRAIWAIYAVCRIVDDSIDVHQDVEYLHKINRDVKAIEHQTTTTFESDDRIMTAFADAATHFQMNFQALYDLIDTVEADQHFEMFETDRGLLDYCYGVAGTVGVLLIPILATPPSDEAYEYGKQLGEALQLTNILRDVGEDYRNGRIYFSKARLNEFNVSIADEIERDQLSDNYIKIWEFYATLADNNYDMVLNHLDVYNEESRMIIELAAQVYRGILTEVRKADYSLKDRAYVSKWKKHKIYRNLKKKYKD",
    "output": "Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress. Catalyzes the head-to-head condensation of two molecules of farnesyl diphosphate (FPP) into the colorless C(30) carotenoid 4,4'-diapophytoene (dehydrosqualene)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSANDFKPETWTSSANEALRVSIVGENAVQFSPLFTYPIYGDSEKIYGYKDLIIHLAFDSVTFKPYVNVKYSAKLGDDNIVDVEKKLLSFLPKDDVIVRDEAKWVDCFAEERKTHNLSDVFEKVSEYSLNGEEFVVYKSSLVDDFARRMHRRVQIFSLLFIEAANYIDETDPSWQIYWLLNKKTKELIGFVTTYKYWHYLGAKSFDEDIDKKFRAKISQFLIFPPYQNKGHGSCLYEAIIQSWLEDKSITEITVEDPNEAFDDLRDRNDIQRLRKLGYDAVFQKHSDLSDEFLESSRKSLKLEERQFNRLVEMLLLLNNSPSFELKVKNRLYIKNYDALDQTDPEKAREALQNSFILVKDDYRRIIESINKSQG",
    "output": "Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of free histone H4 in the cytoplasm. The complex is also found in the nucleus, however it is not certain that it modifies histone H4 when packaged in chromatin. Histone H4 'Lys-12' acetylation is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSESLHLTRNGPILEITLDRPKANAIDAKTSFAMGEAFLNFRDDPELRVAIITGGGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCAENASFALPEAKLGIVPDSGGVLRLPKLLPPAIVNEMVMTGRRMSAEEALRWGIVNRVVSQSELMESARELAQQLVNSAPLAIAALKEIYRATSEMPVEEGYRYIRSGVLKHYPSVLHSEDALEGPQAFAEKRAPVWKGR",
    "output": "Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAVPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG",
    "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNDVWDELQWRGLVAHSTDEAALQEALQTGPLTYYVGFDPTAASLHVGHLVQVLTAKRLQQAGHRPLILVGGATGLVGDPRPSAERTMNDPSVVAGWVTGLQGQIAPFLDFDGPAAATMVNNLDWTQSMSTIEFLRDVGKHFSVNRMLDREAVSKRLATTGISFTEFSYVLLQSNDYLQLHRRHGCTLQLGGSDQWGNITAGCELVRRVDQRTVHALATPLLTKADGTKFGKTESGAVWLDPELTSPYAFHQFWLNAEDAKVVDYLKAFSFRPREEIEELGRQAVENPRARAAQRALAHEVTALVHGEEAAVAVEAAAAALFGGSDLEAIDERILRGALAELPTAAPADRDVRLAQLFADTGLAPSLSGARRTIGEGGAYVNNIKLTDPEATLRDVQLLHGRYAVLRRGKKSLASVAVPLPQ",
    "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSSANNISGAPETGDFTFTQHFNVSATPSEFLASIWPYRHMMWIGPMLLFLAPRFYNTLKNTAFSRAYHMPYSILALHVFISFVDLANYHTQVFLANGAIHPASQIDALICIVQCWTSLYITAQHHLLPKIAMEVTRATFHCMSVQRLFATAMAIRTGDPRWHEASIMLLNNFIWARLLIAYCKMGRFSWKQRYGVGIVGSHLLGMWNGTYPHGIAIYCGLMVVLLNIDGWAKGRDSSVARALRYLGLATPADWYIKVGIDPPTKSAEKKEA",
    "output": "Part of the gene cluster that mediates the biosynthesis of sordarin and hypoxysordarin, glycoside antibiotics with a unique tetracyclic diterpene aglycone structure . First, the geranylgeranyl diphosphate synthase sdnC constructs GGDP from farnesyl diphosphate and isopentenyl diphosphate . The diterpene cyclase sdnA then catalyzes the cyclization of GGDP to afford cycloaraneosene . Cycloaraneosene is then hydroxylated four times by the putative cytochrome P450 monooxygenases sdnB, sdnE, sdnF and sdnH to give a hydroxylated cycloaraneosene derivative such as cycloaraneosene-8,9,13,19-tetraol . Although the order of the hydroxylations is unclear, at least C8, C9 and C13 of the cycloaraneosene skeleton are hydroxylated before the sordaricin formation . Dehydration of the 13-hydroxy group of the hydroxylated cycloaraneosene derivative might be catalyzed by an unassigned hypothetical protein such as sdnG and sdnP to construct the cyclopentadiene moiety . The FAD-dependent oxidoreductase sdnN is proposed to catalyze the oxidation at C9 of the hydroxylated cycloaraneosene derivative and also catalyze the Baeyer-Villiger oxidation to give the lactone intermediate . The presumed lactone intermediate would be hydrolyzed to give an acrolein moiety and a carboxylate moiety . Then, [4+2]cycloaddition would occur between the acrolein moiety and the cyclopentadiene moiety to give sordaricin . SdnN might also be involved in the [4+2]cycloaddition after the hypothesized oxidation to accommodate the oxidized product and prompt the [4+2]cycloaddition . GDP-6-deoxy-D-altrose may be biosynthesized from GDP-D-mannose by the putative GDP-mannose-4,6-dehydratase sdnI and the short-chain dehydrogenase sdnK . The glycosyltransferase sdnJ catalyzes the attachment of 6-deoxy-D-altrose onto the 19-hydroxy group of sordaricin to give 4'-O-demethylsordarin . The methyltransferase sdnD would complete the biosynthesis of sordarin . Sordarin can be further modified into hypoxysordarin . The unique acyl chain at the 3'-hydroxy group of hypoxysordarin would be constructed by an iterative type I PKS sdnO and the trans-acting polyketide methyltransferase sdnL. SdnL would be responsible for the introduction of an alpha-methyl group of the polyketide chain . Alternatively, the beta-lactamase-like protein sdnR might be responsible for the cleavage and transfer of the polyketide chain from the PKS sdnO to sordarin . Two putative cytochrome P450 monooxygenases, sdnQ and sdnT, might catalyze the epoxidations of the polyketide chain to complete the biosynthesis of hypoxysordarin . Transcriptional regulators sdnM and sdnS are presumably encoded for the transcriptional regulation of the expression of the sdn gene cluster ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATYARSVERLIAELSRLPTIGPRSAQRIAFHIIRTRKEEALALAEALREVKERIRPCRRCFNLTEGEECDICRDPRRDRSVICVVEDPYDIGPIERTGEYRGLYHVLGGALSPLDGVEPEDLRIAELVERVRSEGTRELILATNPNTTGEATAMFIAQEVRELPVRVTALASGLPVGGDLEYADEVTLGRAFAGRREL",
    "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MDDNKKKALAAALGQIERQFGKGAVMRMGDHDRQAIPAISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAQAQKMGATCAFVDAEHALDPEYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAIDVIVVDSVAALVPKAEIEGEMGDMHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYGKGIYLNGEIVDLAVLHGFVEKSGAWYSYQGSKIGQGKANSAKFLADNPEICKALEKQIRDKLLTPGVDTKAVGSREAAVADDMAEADADI",
    "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKHTNIPMFRIGIGYDVHRFDNINNDDSNTSITICGIEINYHKKIIAHSDGDVGLHALADAILGAVGCGSIGQHFPNTDQKWKNAKSSHFVIEAQKKAQERGYIISNADIIIICEQPKIMPYALEMQHYIAQFTSIDPSFINIKATTTEKLGAIGRNEGIAAQAIVLCSQQY",
    "output": "Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTMGAGVAVDQAGLSASVN",
    "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTIIRKKHPLIKIINHSFIDLPAPSNISSWWNFGSLLGLCLIIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGIYYGSYNMIETWNMGIVLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDFLGVLILLMAFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSIVILAFMPLLHTSKQRALTFRPITQTMYWILVADLLVLTWIGGQPVEYPFIIIGQTASIAYFAIIVILMPMAGMFENNIMDLD",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSTTFCSSVSMQATSLAATTRISFQKPALVSRTNLSFNLSRSIPTRLSVSCAAKPETVEKVSKIVKKQLSLKDDQNVVAETKFADLGADSLDTVEIVMGLEEEFHIEMAEEKAQKITTVEEAAELIDELVQAKK",
    "output": "Carrier of the growing fatty acid chain in fatty acid biosynthesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTSTLHRTPLATAGLALVVALGGCGGGGGDSRETPPYVPKATTVDATTPAPAAEPLTIASPMFADGAPIPVQFSCKGANVAPPLTWSSPAGAAELALVVDDPDAVGGLYVHWIVTGIAPGSGSTADGQTPAGGHSVPNSGGRQGYFGPCPPAGTGTHHYRFTLYHLPVALQLPPGATGVQAAQAIAQAASGQARLVGTFEG",
    "output": "Probably involved in bacterial recognition and uptake by its host (human) ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MANWLVLAEQVLGGHELTDEEALAILDCPDEELLLLLQGAYRIRSAYYGNKVKLNMIINAKSGLCPENCGYCSQSAVSTAPVKTYKMVDKETLLRGAEEAHRLRIGTYCIVASGRGPSDKEIDTVVSAVKEIKERFGLKVCACLGILKPEQAARLKEAGVDRYNHNINTSKQHHPNITTSHTYDDRVRTVETVKEAGLSPCSGVIIGMKETKRDVVDMARSLRALDADSIPVNFLHAIDGTPLAGTNELNPRYCLKVLALFRYMNPTKEIRIAGGREVNLRSLQPLGLYAANSIFVGDYLTTAGQEKSADYQMLEDLGFEIEFAPAPQAGVVS",
    "output": "Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGPIGAEADENQTVEEMKMEPSGPGHTTPRGELAPDSEPELKDSTKLIEVQIILILAYCSIILLGVVGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYARIWSKLKNHVSPGGVNDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSMTSKAKKNLEATKNGGPDDSFTEATNV",
    "output": "Receptor for neuropeptide Y and peptide YY."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKALWVALVVTLLAGCRAEVEPEPEPEVQLGQEQPEWQGSQPWELALGRLWDYLRWVQTLSDQVQEELLSTQVTQELTALMEETMKEVKAYKAELEEQLSPVAQETRARLSKELQAAQARLGTDMEDLRSRLAHYRNEVQAMLGQTTDELRNRLASHLRKLRKRLLRDAEDLQKRLAVYRAGAVEGAERSVSALRERLGPLVEQGRLGTATTSTLGSQPLRERAEAWGQKLRGRLEAVGARAQDRLDKMREQLEEVRAKVEEQASQMRLQAETFQARLKGWFQPLVEDLQRQWAGLVEKVQQLAVGTTPTPAASKNQ",
    "output": "APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles. Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLRTMLKSKIHRATVTQADLHYVGSVTVDQDLLDAADLLPGEQVAIVDINNGSRLETYVIPGKRGSGVIGINGAAAHLVHTGDLVILIAYGQMDDAEARAYQPRVVHVDSANQVIDLNADTSTAAAGTAGAPVPNPLADPA",
    "output": "Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSERIEWLEDGTAGGSPYSPRFGDRYRSELGGLEQAREVFLKGCGLPNAWAGQPQWCVLETGFGLGLNFLVTWAAWKADPLRPRLLHFVSTEAYPASADDVLRSALTHPELIPFAEQLKRQLWGLLPGVHRLVFEGGQVLLTLCIGDTKAMLREPSFEADSVYLDGFSPQRNPDIWDVHTFKAVARCCRRGTRIATWTIARSVRDALAQCGFVVKKVPGTPPKRDNLQGEYQPAWEVKKSRITPERKAPARCIVIGAGLAGSAVAASLARRGWQVTVLDAASTPAAGASGLPAGVLAPHVSPDDSLLSRLSRSGIRAMLQQADALLQTNIDWSPTGVLEHCVEHARQLPAAWHPGQALADAAGDWTRPATSEQLKHCGLSPETPALWHVQAGWIKPARLVQAWLSSPGVSWHGNAAVSQLVRQAGAWQALDATGNELASAELVVLAAGHGSRALSEIASPQAGRPLALQAIRGQASWGLHAPGTEQAMPAFPVNGHGSLVPRVPLEQGLAWVTGSSFERDNTSPQLRPEDEQHNFGKLKTLLPAAAQALTAQFESGQVRGWTGVRCATPSRLPALGPLENAQDVWVCSGMGSRGLTFAALCAELLAARLHGEPLPVELRQADALLPQYATRLQPSGS",
    "output": "Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDLYAVWGNPIAQSKSPLIQNKLAAQTHQTMEYIAKLGDLDAFEQQLLAFFEEGAKGCNITSPFKERAYQLADEYSQRAKLAEACNTLKKLDDGKLYADNTDGIGLVTDLQRLNWLRPNQHVLILGAGGATKGVLLPLLQAQQNIVLANRTFSKTKELAERFQPYGNIQAVSMDSIPLQTYDLVINATSAGLSGGTASVDAEILKLGSAFYDMQYAKGTDTPFIALCKSLGLTNVSDGFGMLVAQAAHSFHLWRGVMPDFVSVYEQLKKAML",
    "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTLSVSARHRLGTFELDASFTSEGGVTALFGRSGSGKTSMIRIIAGLLRPDEGQISLDGEVLADSGKRLFLPAHKRRFGYVFQEARLFPHLSVAQNLRYGRWFTTGKDTNANDDRIIDMLGISHLLQRRPNRLSGGEKQRVAIGRALLSSPRLLLMDEPLASLDEQRKAEIIPYLERLRDETKIPIVYVSHSIQEVARLADRVVVMKDGKVEAEGKAAEVLSRPDFSTYLERREAGSILSGNIESFDERHGLAAVRLNAALLQVPAKKATAGTPARVLIPARDVMLALVKPEGLSALNILEGHVTGISESEDGMVTIQMDCGGDIIQSRITDLSRERLHLEPGKPVHAIIKSAALDPY",
    "output": "Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFTSNTDDDRGQVGIGTLIVFIAMVLVAAIAAGVLINTAGMLQTQAEATGEESTDQVSDRLEISSTSGDFSDVNTLGAGEGEELEVTVEAGDATAAGEEVVIRVATSAESGFEDSKAIELPDEAGDPTTVTLDNLPSIGGALVTVDGENVQAVTEDSVDLTQGDPSVSFNVDELSDDSESTIGLQLTADAGNNFWDEIAEDNIEDTVTVQLTDYERTEAEITNVNNWGSDDAEIEWEATVPADEGDYAVEVIGFDSARMLPISTNEVASTTEDPELGETDTQIDNLQFSVATAPGSDAIDLEETSVQFIGDQGEETVTITDRNVENIQGVDGNVLTDNSDRALVSFDPVADIDGFNRIEESEDLTVIFTTASGASTETELRIPSTFLEGDESVRL",
    "output": "Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSEKATEIANLLSPTVDSLGVELLGVEYLPAPGGATLRLYIDVPLAEQPERVINVDDCERVSREVSAQLDVEDPISGHYTLEVSSPGVDRPLFTLEQFARHAGESTKIVLKLAQDGRRRFQGEILRIDAEAGAVVFAIDGKDVQIGFDNIDKARILPDWVALGLAPQKPNKPGPKKTGHEKKKPSNESAAGKPRAE",
    "output": "Required for maturation of 30S ribosomal subunits."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDATPNAVELTVDNAWFIAETIGAGTFPWVLAITMPYSDAAQRGAFVDRQRDELTRMGLLSPQGVINPAVADWIKVVCFPDRWLDLRYVGPASADGACELLRGIVALRTGTGKTSNKTGNGVVALRNAQLVTFTAMDIDDPRALVPILGVGLAHRPPARFDEFSLPTRVGARADERLRSGVPLGEVVDYLGIPASARPVVESVFSGPRSYVEIVAGCNRDGRHTTTEVGLSIVDTSAGRVLVSPSRAFDGEWVSTFSPGTPFAIAVAIQTLTACLPDGQWFPGQRVSRDFSTQSS",
    "output": "Specific chaperone for cognate PE/PPE proteins. Plays an important role in preventing aggregation of PE/PPE dimers."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRFNIDEWEPKTTIGRMVKEGQITDIDYILDNNLPILEPEIVDALLPDLEEKVLDVKLVQRMHKSGRRARFRATVVVGNRNGYVGVGKGKAKEVGPAIRKAIAQAKKNIIRVKRGCGSWECGCGTPHSIPYKGYGKCGSTAIEILPAPKGVGLVAGDVAKAVLGLAGIKDVWTKTFGETRTTYNFAMATFEALKSLNFTRTMEKHKEKLGIVEGRVL",
    "output": "With S4 and S12 plays an important role in translational accuracy."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MATTLTTDLRLSIAHQTRFGLRLASAISSDPESAATNVAFSPVSLHVALSLVAAGARGATRDQLVAVLGGGGAGEAEALQSLAEQVVQFVLADASINSGPRIAFANGVFVDASLSLKPSFQELAVCNYKSEVQSVDFKTKAPEAASQVNSWVKNVTAGLIEEILPAGSIDNTTRLVLGNALYFKGLWTKKFDESKTKYDDFHLLNGSTVQTPFMSSTNKQYLSSSDGLKVLKLPYQHGGDNRQFSMYILLPEAHDGLSRLAQKLSTEPDFLENRIPTEEVEVGQFMLPKFKISFGFEANKLLKTLGLQLPFSLEANLSEMVNSPMGLYISSVFHKTFVEVDEEGTKAGAATGDVIVDRSLPIRMDFVANHPFLFLIREDIAGVVLFIGHVANPAVSS",
    "output": "Inhibits chymotrypsin in vitro."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSQPLETFDVIVIGAGWYGLMAARTFLELAPDTNLLILDDGKTVGGVWSKERIYPSLFAQISHPLFEYSFYPMPEEDISPDGFVSGKTIQKYLEAFAKDHGLILHLRLETRVEKVKRGVNSNEWILEIKGDKPLACSKLIYATGANSSPIIPKWPREGFEKPVIHSLDLGRYQDYIANNVQKAVVVGRSKSSYDAVYHLLCAGKKVNWVMRDGQSGPFSLYAPTFMGLWNIADHISTRFASSFSPCIMSTDGFCYNFFQRSALGRVLTNMYWRTANYLSVSHAEYWRTENSEKLRPRPYSDGVFWGSGGIGIATAPDFWETFHRGDVTIHSTEIESVSHKDVTNLKNGYSIATDIIIHCTGFDKGYGAFDPQLRNELGLEYNTKEFSRWTMLDEKADQTVDRLLPYICDSPNQYGDSEASRSTGQGPNRHYRRLVVPELAARGDRSILFPGHIHSAFTPLAAELQALWGVSWMLGWRDLPSKEEMETEAANFNAWTRKRYLEQGRKHSYFIYDYIPYIDTLMKDLGLDPFRKSNVFEEWFVRYKPSDYKTILEEYRSVRRHEREMERSGEESVARMKRCD",
    "output": "Part of the gene cluster that mediates the biosynthesis of depudecin, a highly oxidized eleven-carbon linear polyketide that acts as a histone deacetylase (HDAC) inhibitor and makes a small contribution to pathogenesis . The reducing polyketide synthase DEP5 is the central enzyme in depudecin biosynthesis by yielding the backbone polyketide chain . The monooxygenases DEP2 and DEP4, as well as the uncharacterized protein DEP1, then act as tailoring enzymes to modify the intermediate polyketide chain into depudecin ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MATIQEIECDFLAKIAQKFTNAEIELINKAFYHAKTWHENQKRLSGEPFFIHPLRTALSLVEWNMDPITICAGLLHDIIEDTDQTEANIAMIFSKEIAELVTKVTKITNESKKQRHLKNKKENLNLKSFVNIAINSQQEINVMVLKLADRLDNIASIEFLPIEKQKVIAKETLELYAKIAGRIGMYPVKTKLADLSFKVLDLKNYDNTLSKINKQKVFYDNEWDNFKQQLKKILAQNQIEYQLESRIKGIYSTYKKLTVHEQNISKIHDLFAIRLITKSELDCYHILGLIHLNFLIDSKYFKDYIASPKQNLYQSIHTTVRLKGLNVEIQIRTQQMDNVSKFGLASHWIYKEQKEGLLAPALQLNYLVTKQKHSHDFLKRIFGTDIIKINVSASHEPNVIKQINVDSNNKLLDIAFENYPKQFAKLTKIEIDGVEINSFDTSVENEMLIEFYFGKNNNLKSKWIRYMNNPIYREKVKKSLAKLAKSGRYSELAFYEKELGEKQLKLASETEIQKRLNTLRIKKMSDYLALIECTNFTNDEHLLFLAKNNDKWNKLTKPLKFAFSKVVFHNSYFEQIEGIFITKIVIEPCCSKIPDMPEQVTGILTKNILSVHRYGCKNLQNKKQLKIIPLYWNIQQLKLKPRKFRSYININGVWSEKTINKICQTIINGDGYIEKIIPKINKQKDEFDLNITLFVNNYQQLLTLMDQITTKNISFSWKYL",
    "output": "In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the degradation of ppGpp into GDP. It may also be capable of catalyzing the synthesis of ppGpp (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNNRMLSFPSMLFLLAFGIVLSVSAGTTHADELANQTAKVADEASIVVSTSQAAVEQTQSQEKEISPAMEEDTSNLSLKPNAQQESQSPDSSTELQDPAEQTPPETSDASAPATTSADSVEKYAQDATQNQSSTSNGPGVIRATSAQVTATRSVVSSQSGDAIVDLSADKASYRQGEDVNLSVDFKNTTDKEQDVTVYADVYYIDNKLGTYKFSKHLKAGEGYKMQSGDLKIPASQFENNHGYLLKVRVRDADNNTLSEVNKAIAVESDWTKFPRYGIVGGSQDTNNSLLSKDADRYRAEIEKMKNMNINSYFFYDVYKTATNPFPSDEATFKQDWNTWSGSEIDTQAVKDIVNQVHDGGAVAMLYNMILAENTNTGEAPVLPETEYAYNSDDRGYGAQGQPMSYTVKIPKDGQEEDVEIQRYYNPTSKLWQDYIADKMGQAMKNGGFDGWQGDTIGDNEVYSYADKDSNDPSKKFWLTEGYAEFLRAIKEKLPNYYLTVNDVNGEQIYRLKDGNQDVIYNEIWPFGPALPSEMAAVKPNTVTSRPVLTKVRQGDWKISIVGAYMEGSENGGSKADAEAGKSLQTDAVLLTSASIAAAGGYHMSLAALANQQDETDGGQGIGVLQTAYYPTQSLKTSSELTRKNNDYQQFITAYENVLRDGVENDDAQVNTFDSNGQKLSTDAKGITGNQVWTYGKKGDNFRTVQLLNLMGINSDWKNEDGSAANKTPDEQTNLTVKYALGDVSMEDAQRMANQTYVTSPDDWSKSNLQKVSASVKTDENGKPVLVINVPKLTLWDVVYISNANQESAPEADQAQTPAAQSSDDKVAENETSQPAAEDAKEQTSEPAQDQAAPAEQGQAINQAESPATEPEAEVTPATAEPAKVDAPEANQAADQAVSPEPASQEQAASQSQPEANQTPASNETPATQGNSEQPELNEPTAQTQPSSQVSPANTSVTPVAEQPTNQGQAADKADQAPTNSTSTPESTSPVEPAATDQSSDTPIVTAGNLSVQPAETETPTVPDKQGDSKANQSSTETPVADQVPAVAEQPQATEPNQAKPSVDKAAAPEALSLIQLKQQTPAIQAKEADDPEVDETKSEVTPDSGTDKAPEAGQVDSDKAPTVKPSTPENNDNQPNNANDADKNKTNEADSNKANQDSTKGSSADQSGKSTTPEDGPDNSSPEDPETKPSDPNTDTSDQEQVKPSLPVVPNQTVDDPKTDDTDTPANTDSAKSKKVADADKNKVATDSEGRQKSSEFPKEATDLEKVGQPASPQVAGVKSSVATSPEKKSEPVSKTSTTSSSDKLPKTGDHKTVVLIIVLGLVFVGMTGLLARHEKK",
    "output": "May play a role in sucrose-independent adherence to the pellicle-coated tooth surface."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDYQYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSGLQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHEFFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFRMKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDCAQEKMSILAMINNMQQ",
    "output": "Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRWRLSKPQAATSIEQSKGSFEDAIRRNLLFAQLQDLVAWGRKNSLWPYNFGLSCCYVEMVTSFTSKYDIARFGAEVIRATPREADLMVISGTVFIKMAPVIKRLYEQMMEPRWVISMGSCANSGGMYDIYSVVQGVDKFLPVDVYVPGCPPRPDAFLEGLLLLQEAIGKEQRPLSWAIGPQGVERAPKPSLRDQRRAERQKATVFRSPDEV",
    "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNLRDNLRRLLVRFYARRVEGHLDHDQVPKHIGVIMDGNRRWAKAAGSTTAQGHRAGADKIEEFLGWCSETDVGVVTLWLLSTDNFDRPQEELGPLLGIIEGVVRTLAADGRWRVHHVGTPDILPSQMQNALKEAEETTAHVDGILVNVAIGYGGRQEIADAVRSMLLDAHEKGTSIPDLADAVDVDLIGKHLYTGAQPDPDLVIRTSGEQRLSGFMLWQTAHSEYYFCEVFWPAFRKVDFLRALRDYAARHRRYGN",
    "output": "Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSSQEKLLKTVIRPHVSDKTYGLSDANSTIVFEVARFANKQDVKNAVEKLFEVKVESVNILNVKGKARRFGRVEGRTKAWKKAYVKLAEGHDINFVGAE",
    "output": "One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MMDAEKVSTDGEAISEGEVGSNGETPPETEVEFIGETAPDTDVEFIGETSPGTDVEPTGESIQETEVESIGEATPGMDVEPIKKTMTELNVESIGEETSETDVDSIRKALRGIDLESITVAYPPKKAKHRKVRPQAEVESTGRAAPEGELEVSDHEKVEALLDELDELSEIVSSPEVSYSDISPLEMGEDDTNVSATSTDTFQQGIYEPIEPIEPTEPPEPAEPPKPAETPEDSTVRAPAHPYQRDFPMGARHRFRLSIMGSLTPSDTDDLPLETDEPPQQESVQSTPRALEETRIQFLDQVQSLSPEALLDRATEGSDEAEEEGSQLIVLDPDHPLMIRFQEALKGYLNRQMDKLKLDVQELDVATKQTRSQRQELGVNLYGVQQHLARLQMQLEKSHDRHSLVACERRRKEEELQCARSVYNKTCQTANEERKKLAALQTEVESLALHLFYMQNIEQDVRDDIQVMKQVVRKTETEKMHAEVEKKKQDLFVDQLTERSHQLEENIALFEAQYLSQAEDTRVLKKAVTEAITEIDTIAVEKKRILQQWTTSLVGMKHRNEAYKTVMDALRECQHQVKSTDSEIEVCKKSIMQEEEKNEKLARLLNRAETEATLVQKMTAQCLSKQEALQTEFNTYQLALQDTEEMLNKGYVEHSAVLSELQATRQAFHQEQELRQKMDMSMVDKLQEQGTSSKMTKYFHQLLRKLQKENTNLVTHLSKIDGDIAQATLDITNTNCKIDMHKKTLAEMDKEVKRFNDLITNSESEIARRTILIERKQSLINFFNKQLEQMVSELGGEEAGPLELEIKRLSKLTEEYNTGVAEAQMTWLRLQQELVQVTHEREEQLVSVDQLKKEVHIMEQKKLRIESKIAHEKKEQKIVSRHMRDLDNDLSKLNMLLDKNRCSSEELEQNNIATETEFLRTLKDSERETIQMQEKLMELSEEKATLLNSFMEAEHQIMLWEKKIQLAKEMRSSVDSETGQTEIRAMKAEIHRMKVRHGQLLKQQEKMIRDMELAVARRETIVVQAEGQSKIDKKVITKTEFHYQQRELQKKVREMHKATDDCTNTISELEETQKFLSSSLQEKQQLLSEMQATTDVLEEEINQLTALKRQNLLEIVTLQTRGKHLQAAIEGKYVFLHRNSRSQLMERKRLSVRLSQLNKVLSSVQEDYPQYQEVLQSIQQKIATKLETPEPS",
    "output": "Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKANIHPDYHTIKVVMTDGTEYMTRSTWGKEGDTMNLDIDPTTHPAWTGGSQTLLDRGGRVTKFKNRFGNLGI",
    "output": "Binds the 23S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDESVDRVLAGKYPAKAHAKRVAARIRELGYGESGVIYLEGQKTQMIEDNDGSMPFRQRRNFFYLSGCPLPDSYLTYNIEEDHLTLFIPPIDEDSVIWSGLPLSPDEALEMYDVDAVLLTTDVNTSLAHFCSVKKGKKVFAIADQVSPHITFLPFQETDFDVLKRAAEESRVVKDTYEIALLRRANEISTKAHVAVIKAARSAANERELEAIFIATCMSYGCREQSYHPIFASGTNAATLHYQNNNEDLVDKTTGEKRLNMLVDAGGEYRTYCADITRVVPLSGKFSAESRQIYDIVLDMQMTSLAMIRAGVMWEDVHSNSHRVAIRGLLKLGILRGTEEELFDKGISVAFFPHGVGHYLGMDTHDTGGNPNYKDENPKFKYLRLRGTLACGAVVTVEPGIYFCRFIIDPYLASPELGKYIDTNVLERYWNVGGVRIEDNVVVTQNGHDNLTAAPKIPEEIEKLVAAAQ",
    "output": "Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MANPLRKTMVYLGLADEELDYQQGQQPAQQQQSPVQAVPTPAPAPQQQAKRAPVTPLHKPSTTTRNAAPAEMNEILTVHPKAYKDAQVIAENFREGVPVIINLSQMTDDDARRLIDFASGLSIGLYGKIERVTAKVFLLSPSHVAVSGEQSATEAEVEASFFGR",
    "output": "Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALVWHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLKPSVPLFRLEDTGMGEQMQEYAVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRFPLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITRPAEAVEYISRTIAQLEKGERVCGQVDRARGY",
    "output": "Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKQFLDFLPLVVFFAFYKLYDIYAATTALIVATAVVLIYSWVRYRKVEKMALITFVLVAVFGGLTIFFHNDEFIKWKVTVIYALFAGALLFSQWVMKKPLIQRMLGKELSLPQQVWSRLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLVFTLLSGIYIYRHMPQDDHH",
    "output": "Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSSAPHIPVLGREAIDHLAPREGGIYVDATFGAGGYSRAILDVPGTRLIAIDRDRTAIAGGAELVERSAGRLTLVEDRFSHLADVCAAQGVDAVDGVVMDVGVSSMQLDQAGRGFSFRLDGPLDMRMGQAGPTAADVVARASEADLADIIYLLGEERHSRRVARAIVADRQETPFTTTRALADLVGRVVRSKPGDIHPATRTFQALRIFVNEELEELQTALTAAERVLKPGGRLVVVSFHSLEDRIVKNFLAERSKTGGGSRHLPEVAQTAPSFQLLTRRPVVAGEDEVAHNPRARSAKLRAAERTSAPAHKDDQSSSWPRLSDVMRGG",
    "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNPVRQPYDLAAPAPNGMRRGRTTGSCATAAVKAALMLLLDGVDADEVFISLPDPDFYLAVPVESVAWLDENTVRAEVLKYAGDDPDNTDGATIFAEVKLNSSGALRFLAAPGVGMVTQPGLRIPPGEPAINPVPRQMMRMAVDEVLAGRPDPGIDLAIGCVDGDKIAKRTFNPMLGIVGGISILGTSGIVEPMSQAAWIASIEVYVRVALGELPPAIAFTPGKIGRGYAADTLGLEKKQVVQIANFVGDSLDFAESVLIEQGRILDTLWVLGHPGKIAKLLDGVWDTHSGKSGMAMDAVAGVAADLGYPSELVAQIKQANTVENVVQIMNSQPDTRGYWMEIERRTAARMATKVPSVRQVAVRLFSMDGTPLGEAA",
    "output": "Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MFRPQVVGVTGRTDLGRAVRVAERVCRLCDREGFEVLVDDSLGIGEYPRVNLKDMGKEVDMIITIGGDGTILRVSRITSEYEVPILGVNLGKFGFLTEVSESGLKEAVSRLARGDFNLEEHRKLRIKIGGSDEGDALNEVTVITSRPAKMIRYRLSIDGFELETTWADGVLVATPTGSTAYSLSAGGPIVEPQVECSIITPLNPFKLEARPMVVSMDRRVEIDVDDPERAEVVVDGQEYMNLDGTVSVTRSPNVARFIRFGSTYFERLKEKFLRWD",
    "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAISAKLVKELRERTGAGMMDCKKALTETDGDIDKAIDYLREKGIAKAAKKADRIAAEGLVHVEVKGNEAAIVEINSETDFVARNEGFQELVKEIANQVLDSKAETVDALLETKLSSGKTVDERMKEAISTIGEKLSIRRFEIRTKSDNDAFGAYLHMGGRIGVLTVVEGSTDEEAAKDVAMHIAAINPKYVSSEQVKEEEINHEREVLKQQALNEGKPENIVEKMVEGRLRKYLQEICAVDQNFVKDPDQTVEAFLKSKGGKLVDFVRYEVGEGMEKREENFADEVKGQMK",
    "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MARIAGVNIPNHQHTEIGLTAIFGVGRTRSRSICVAAGVDFSKKVKDLTDADLEKLREEVGKFVVEGDLRREVTMNIKRLMDLGCYRGVRHRKGLPMRGQRTRTNARTRKGPRRAAQALKK",
    "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKSGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK",
    "output": "Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRLYFSAFRHPKRLGLCLLITLSIILLGWQCVLLYNHSPEIQRSVYTLTGLAPSSKMAFVTMLTVRAANGENEVENTQQDWYYNSTRLLVHRLVKFKPTKSKYPVVVLAMKGIDQWKLDQLQEDGAIVKVVDPLYAHEVVDDVNDIALLDSRWSMMFTKLRVFEMYEYDRICFLDSDILPIKKMDKVFDVHQLSYSKDSVLFPPTLFYKPRRSIFWRRFTEEFAAYGLTRDDLYPYVFAAVSDPGMWHETPPPFKDYFNAGLFVFKPLKAHYKRLMALARFPKLYDNANMMEQSLLNFAYNSAGAFPWESLDWTFNGLWARKNDLPYLKAVHGKHWQPEGSLGYDEDTSKLWWDAFQEMQTYHDQQRNADLY",
    "output": "Has a role in meiosis."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MFLVIGAILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGESGFSLYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNSFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLMFKVRERVY",
    "output": "Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKLIAFDQEAREGLQKGVDALADAVKVTLGPRGRNVVLDKAFGGPTVTNDGVTIARDIDLEDPFENLGAQLVKSVAIKTNDIAGDGTTTATLLAQALVNEGLRTVAAGANPIAVNRGIAKGTERVVELLRELAQPVADNAAIANVATVSSRDEKIGAMVADAFDKVGKDGVVTVEESQSIEDESIVTEGVSFDKGYLSPYFVTDQETGHAELENPLILLVREKISSLPDFLPVLEKVANSGKPLLIVAEDIEGEPLQMLVLNAIRKSLKVAAVKSPYFGDRRSAFMDDLAIVTGGTVIDSELGHKLSETTLEQLGSARRVNITKEETVLVDGAGSAEAVEERRNQIRNDIERTDSSWDKEKFEERLAKLSGGVAVIRAGGATETEVNERKLRIEDAINAARAAGQEGVIAGGGSVLVQIADEIEELSRKEEGDEGIGLRSLARALRRPAYWIADNAGLDGAVVVSKIAEQPNGSGFNAATLEYGNLLEQGIIDPVKVTHSAVVNATSVARMVLTTETAVVDKPAAPAGQAGAHAGHAHAH",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKDLTAKQRSVLIFIEEFIEKNGYPPSVREIARRFRITPRGAQLHLVALEKKGYIERKNGKPRAMRVTKSVKNRVPLIGEIRAGEKKEAIEYLEDYIEVPGSFLSSGYEHFLLRVKGESMIEEHICDGDLVLIRRQDWAQNGDIVAAMVEGEVTLKKFFQRGEMVELRPANKEMSPMFFRADRVKILGKVVGVFRKI",
    "output": "Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAYPFQLGLQDATSPIMEELMNFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAVILILIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKNFENWSTSMI",
    "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MANDAEDAVRSYLTSVKEDLMTGVSFMIPFVTIGGIFLALGYAVASLSNNVQDVFNSTGTAGWFLAQIGVAGLTLMVPVLGAYIAYAIADRPGLAPGFILSYIIQQGNVLQAAGDVIGLQGGSAGAGYLGAIVAGFLAGIVARWFKQRDVPEFIAPMMPVLLIPVATTAVLTPVMLFVLGVPISIANAGLTEFLSNMQGGGQAILLGGILGAMMAADMGGPINKVAYVFSVGLISEGVTAPMAAVMIAGMVPPIGLALSNFIAPQKYAAEMYENAKSGVLLGFSFITEGAIPYAAADPARVIPSVVAGSAVAGAASMALGVNMPAPHGGIFVVPLSNQPFMFIACILLGSIVTAVIATAIKPNFDAKMAAQSSDD",
    "output": "The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II PtfABC PTS system is involved in fructose transport."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MPATMVLTAPSLLSSSALIVLAYLIGSIPFAVVVSKLMGLQDPRSYGSGNPGATNVLRTGNKTAAALTLLGDAAKGWFALWLARALVPELSWGAYALVALAVFLGHLYPLFLRFKGGKGVATALGVLMAIEPWLAVATIATWLIVAVFSRYSSLAALVAAFFAPVYYVFGSGAAWHARLEVGLAIAVISALLFYRHRANIARLLKGTESRIGKKK",
    "output": "Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKELVELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVFNMNKPGALRRVVMGEKEGTLITE",
    "output": "Catalyzes the reversible phosphorylation of UMP to UDP."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAASLVRSCCSRASRAITTVRFMSNVPEDTVYGGPKPQNSNQRVTLTQLRQKHRKGEPITMVTAYDYPSAVHIDTAGIDVCLVGDSAAMVVHGYDTTLPISLEEMLVHCRAVARGAKRPLLVGDLPFGTYESSTNQAVDTAVRVLKEGGMDAIKLEGGSPSRITAAKSIVEAGIAVMGHVGLTPQAISVLGGFRPQGKNIASAVKVVETAMALQEAGCFSVVLECVPPPVAAAATSALNIPTIGIGAGPFCSGQVLVYHDLLGMMQHPHHAKVTPKFCKQYAQVGEVINKALLEYKEEVSKHLFPGPSHSPYKISSSDLDGFLSELQKLGLDKAASDAAASAEKMDHSDSPSSQ",
    "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSRVGKKIIDIPSDVTVSVEGNTITVKGPKGELSRTMNERMTYKQDESTLEVVRPTDSKDDRTVHGTTRALINNMIQGVKEGYQKTLELVGVGYRAQMQGNDLILNVGYSHPVEIKADDGITFGVEKNTTVTVAGISKEQVGAIASNIRSVRPPEPYKGKGIRYQGEYVRRKEGKTGK",
    "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MYTLLSGLYKYMFQKDEYCILILGLDNAGKTTFLEQSKTRFNKNYKGMSLSKITTTVGLNIGTVDVGKARLMFWDLGGQEELQSLWDKYYAECHGVIYVIDSTDEERLSESKEAFEKVVSSEALDGVPILVLANKQDVETCLSIPDIKTAFSDCTCKIGRRDCLTQACSALTGKGVREGIEWMVKCVVRNVHRPPRQRDIT",
    "output": "Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTSQAIQLIDVNKEYNKESLEYFKQCVGTRDVGFNYHVISVFGSQSSGKSTLLNILFNTQFDTMDAQVKRQQTTKGIWLAHTQNVNNHKSTTDTDSDYFILDVEGSDGAERGEDQDFERKAALFAISVSEVLIVNMWEQQIGLYQGNNMGLLKTVFEVNLSLFGKRGNDHKVLLLFVIRDHVGVTPLKSLQESLITELEQIWSELNKPTGCEETTLYDFFDLEFKGLGHKLLQEEQFYDDVKSLGDSFIDSESNEYLLKPNYHHKLPIDGWNMYAEQCWEQIENNRDLDLPTQQILVARFKTEDIANEAYAKFTEEYETETEKRINDKTELVSYLKKIKDECLGEYDEHASRYAKAVYEEKRIELVDKVNERLFTTASKYLDMLTAVLLTKLENGMKEKENIKLPFEDRYLKLFKDIEAEFDAAITEFFSKDLLTKIKDFELKFAADVHEKKLQLRESELNALLSKIKKQLTLRIKDEEIELLSKPTPDLWDKVTDTFENIMKKTLSRFATGEGEYEFKMGLSEDENKKQYHAIRAFAWTLLETVVHDYLKEDTIVSLLRDRFESKFRYDSNDVPRLWKNEDEIDQSFRVAKEHALEILDILTLAVKTDGTEVIPDAFEDEPNEGLIYDDSHDVYHSNRFAHILNETQKEKVQQQFRRQINVTVLDCKRSIVTSSTHIPIWIYAVIVVLGWNEFMIVIRNPLFVTLALLSIVSFYFIQKFGLWGPVMNVVNTALGESRTTIKEKLRQFVLEEHELKKTAKVEEEIELQDLSKNSSSSGNEDSD",
    "output": "Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MRLVLLNYGIWHDRRSALKFTDIDYFVFSDASKYVSIGMSPYMRDTYRYTPMLAILLLPTQYGFPSWGKYLFSISDLIAGWLMIKLLSRRISYKRSLIYSSFWILNPFVAIISTRGNCEAILGILSIALLYLIEKKSVWLASLILGFSVHFKIYPFMYGIAFLVYFSKPKKGSTFMEKFLSLLSINQLKIVVGSLFMFTICNLLMYYLYGSPFLEHTYLYHFGRTDHRHNFSLHHLNLYYESSFGAKASSLFAFLPQLSLCMLIPLVFGKKNLPGTLFAQTFAFVTFNKVCTSQYFMWYLVFLPLVLPNSKLLSKKGLICLSLWIIGQLLWLISAYNLEMLGKSVFIPLWLSGLLFFFFNVYELKIILDSL",
    "output": "Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKYLIRARLEVDGRVEKHDVIGAIFGQTESLLGSDFSLEELQNKDKLGRIHVELKYQGTKTIGSISVPSNLSRVETAIIAAMLETIDKIGPYPAKITIEEIRDLRLERLEKIKQRARELLRLMKEKEPDIREIIREVLQEEQAKAQVAKLVEYGPERLPAGPGVEKADTIIVVEGRSDVNTLLRYGYTNVIALGGAREKVPETIKRLAEQKKVILFVDGDRGGELILKNVLPQMKVDYVARAPEGREVESLTGREIAQALSQMKPAEIVARELGIEAAEKPAEEAVKREEEAAAEAKPPAPAVQEKAAKPPEEKPPTVKFTIPKAVLEAAKELRGTLEAIVYDKEWRELDRLKVRELYDYISKSEPGRIYAVVFDGIITQRLLDIASEKGVGIIIGNRIGNKITHKPTNVKFLTFSDLF",
    "output": "RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MISIMDRSEIVARENPVITQRVTNLLQTNAPLLFMPIDIHEVRYGAYTLFMYGSLENGYKAEVRIENIPVFFDVQIEFNDTNQLFLKSLLTAENIAYERLETLTQRPVMGYREKEKEFAPYIRIFFKSLYEQRKAITYLNNMGYNTAADDTTCYYRMVSRELKLPLTSWIQLQHYSYEPRGLVHRFSVTPEDLVSYQDDGPTDHSIVMAYDIETYSPVKGTVPDPNQANDVVFMICMRIFWIHSTEPLASTCITMAPCKKSSEWTTILCSSEKNLLLSFAEQFSRWAPDICTGFNDSRYDWPFIVEKSMQHGILEEIFNKMSLFWHQKLDTILKCYYVKEKRVKISAEKSIISSFLHTPGCLPIDVRNMCMQLYPKAEKTSLKAFLENCGLDSKVDLPYHLMWKYYETRDSEKMADVAYYCIIDAQRCQDLLVRHNVIPDRREVGILSYTSLYDCIYYAGGHKVCNMLIAYAIHDEYGRIACSTIARGKREHGKYPGAFVIDPVKGLEQDKPTTGLDFASLYPSLIMAYNFSPEKFVASRDEAKSLMAKGESLHYVSFHFNNRLVEGWFVRHNNVPDKMGLYPKVLIDLLNKRTALKQELKKLGEKKECIHESHPGFKELQFRHAMVDAKQKALKIFMNTFYGEAGNNLSPFFLLPLAGGVTSSGQYNLKLVYNFVINKGYGIKYGDTDSLYITCPDSLYTEVTDAYLNSQKTIKHYEQLCHEKVLLSMKAMSTLCAEVNEYLRQDNGTSYLRMAYEEVLFPVCFTGKKKYYGIAHVNTPNFNTKELFIRGIDIIKQGQTKLTKTIGTRIMEESMKLRRPEDHRPPLIEIVKTVLKDAVVNMKQWNFEDFIQTDAWRPDKDNKAVQIFMSRMHARREQLKKHGAAASQFAEPEPGERFSYVIVEKQVQFDIQGHRTDSSRKGDKMEYVSEAKAKNLPIDILFYINNYVLGLCARFINENEEFQPPDNVSNKDEYAQRRAKSYLQKFVQSIHPKDKSVIKQGIVHRQCYKYVHQEIKKKIGIFADLYKEFFNNTTNPIESFIQSARFMIQYSDGEQKVNHSMKKMVEQRATLASKPAGKPAGNPAGNPAGNALMRAIFTQLITEEKKIVQALYNKGDAIHDLLTYIINNINYKIATFQTKQMLTFEFSSTHVELLLKLNKTWLILAGIHVAKKHLQALLDSYNNEPPSRTFIQQAIEEECGSIKPSCYDFIS",
    "output": "DNA-directed DNA polymerase involved in viral DNA replication."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTSFNDGRTVHVVIPARYGSTRLPGKPLVDLEGEPMIVRVHARVRRALPEADIVVAIDDARIAEVLDARGIRFAMTDTGHASGTDRAAEVARVSGWPDTDAVLNVQGDEPLVPTALLQAFAGFCGATAALGVATVACPIGEVALLDEPAIVKVVVDHRGRALYFSRAAIPFCRDGRPADSAGSNGLFLRHIGLYGYTNATLQALSRAAPCELEQLEKLEQLRALWLGMPIDVMRWPDAPPAGIDTPDDVARVVSLLKRQTHDATEPY",
    "output": "Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAVLLMRLMLQTTKLDHNLIGRCLQRHAVKPDPAQLSLSASTPKLLYLTSAKGFSTAGDPQGERKQKRRDAFSNTGRKISERIIRVLDEKGMDLGMMHRADVIRLMNKQDLRLVQRNTSSEPPEYQLMTGEQIHQERLKLREQEKAKPKTGPTMTKELVFSSNIGQHDLDTKSKQIQQWIEKKYHVQVTIKRRKDAEQSEEETEEIFNQILQTMPDIATFSSRPKAIRGGTASMCVFRHLSKKEEKAYRESQESQRRDTLSKDDDGNSKESDVVCQ",
    "output": "IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARRPRNSRAWRFVLSGVRRDQDGRSPALHAEEEAWGYDSDGQHSNSDSDTDLLTLPPSIPSAVPVTGESYCDCDSQNDPYCSSLHPFRQIKSCQCGEEDNYFDWVWDDCSKSTATVLSCDDRKVSFHMEYSCGTAAIRGNKMLTEGQHFWEIKMTSPVYGTDMMVGIGTSDVNLDKYRHTFCSLLGKDAESWGLSYTGLLQHKGDKSNFSSRFGQGSIIGVHLDTWHGVLTFYKNRKRIGVAATQLRNKKLFPLVCSTAAKSSMKVIRSCCCRTSLQYLCCARLRQLLPGSVDSLEVLPLPPGLKQVLSNKLGWVLQMGSNRSSQHKGDGSATTSCGSYSDSSCTPGHDNCQRKRCRRI",
    "output": "May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGHGRRISESIKKQLPVTGPEAPTVKNLMDWYLNNTNTHGCRRIAVSRGYLRRWIWICFTVSSVGMIFWQWTLLLMSYYTVSVSVTVQFQTLPFPAVTICNINPYRKNATSALLEELDKQTKLILKELYTSCTGCSNRKLRSVLLNEAPEEDSGVAKLLQDMPLMKFEVIKEDHVIVSELSSNRQYRINNTFITRMYNNMDLATVGEQVGFKICDANKSNCIIYTFNSGVTAILEWYRLNYLNIMAQIPNEKKLEMGYSADDLIVTCMYDGQSCDSRNFTLFQHPLHGNCYTFNSGDDGNILQTLTGGSEYGLKLTLYLENDDYNPYLFTSMGAKIIVHDQTEYPLVDDVGLEIQTATETLIGLQVTTSAKLSKPYSDCTMDGSDVLEQNLYNTSYSLQICLHSCFQTEMISNCGCAYYEQPLPSGAEYCYYEKYPGWIYCYYQLQDKFVNERLACQDICKETCNSKDWDLTKSLARWPSVASKDWVLNLLNWERGLNNTLNKNDLASIAIFYQDLNLRSLSESPANSIATLLSNMGGQLGLWMSCSIVCFLEMWEVFLVDILTIIARYWLHRGRQWWRKRKERQMQQPSPPDHDTGHHNPVCIDDEDPPTFHTAMQLPCVQTGPVPSTPPPQYNALRIQSVFDEQVSDTEVN",
    "output": "Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MANLKVMDQNGKDSGEVTLNDKVFGIEPNDNVVFEAIIRQRAGKRQGTSKVKNRSAVRGGGKKPWRQKGTGRARQGSIRAPQWRGGGTVFGPTPRSYAYTMPRKQRRLAIKSVLSQKLIDNDLIVLDKLTMSAPKTKELVSMLNSLNADGKVLIVSDDNNVQLSARNLAKVKVVPVNGLNVEDAVNYGKLILTQDAVKKIEEVLA",
    "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGYERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETWQHLKGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEELAGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQEKAETLAKLFIDNFDKYTDTPAGAALVAAGPKL",
    "output": "Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MADPKTKGRGSGGNGSGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFATPQQGRTLGLDPETGHEIVAREGRFGPYVTEILPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGNDSRSLVTEDQIFTITLDEALKIYAEPKRRGRQSASAPPLRELGTDPASGKPMVIKDGRFGPYVTDGETNASLRKGDDVASITDERAAELLADRRARGPAKRPARKAARKVPAKKAAKRD",
    "output": "Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex . Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVNFYDDVDESKSHGEFPLIPVVLQNSSELSVRTIPTGNEIIESVHLTKWLRKYRNALASQLDRYEKGWQSKIANFRLQVQHVINYSRKNIFNVDSENKHTVVPGSLIALGAFFAGSIAVNRSNWGAKRLIFGHKSSILEKLCTSLPSRILLPWVLAAATFKYWAPQTSQNLVNATENDLLPADFVKSYHNTWKRIYEEGYVAKKCDLKRQIDQTLQKNIRYAREQLYEKLEQA",
    "output": "Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSRNFYNYDPTVDILQPPLIPDVILKSNLKELTLPTGNQVLESLPLTAWFHRTRSNIISHLTRYEAEWETQKSAARNELHSVKSYLKGNIFNDARELYALPETNILTICAYFAGRIITNRKNWGVSAATLQSVKSSVHRPSLMARVCTSIPSKMVLPWAMAGAVFKELAPTAFDNTITSLESDILDPGFVAQYKTLWRDYYTNGAKKASIEAAELLEGKLQGYIGFARNFIIYSTR",
    "output": "Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKTSILFVIFSLALVFALSPATEIEETDRACGQFWWKCGEGKPPCCANFACKIGLYLCIWSP",
    "output": "Moderately inhibits voltage-gated sodium channels and weakly inhibits voltage-gated potassium channel . Inhibits the inactivation of rat Nav1.2/SCN2A (IC(50)=870 nM), rat Nav1.3/SCN3A (IC(50)=845 nM), rat Nav1.4/SCN4A (IC(50)=339 nM), human Nav1.5/SCN5A (IC(50)=335 nM) and human Nav1.7/SCN9A sodium channels (IC(50)=348 nM) . The toxin delays the inactivation of sodium channels without affecting the activation and steady-state inactivation kinetics in the physiological range of voltages . Site-directed mutagenesis of the sodium channel indicates that the toxin interacts with site 3 located at the extracellular S3-S4 linker of domain IV . On potassium channels, it inhibits activation of channels with an IC(50) of 8.05 uM through a voltage sensor-trapping mechanism . It increases muscle contraction in several assays (mouse phrenic nerve-diaphragm, toad heart, rat vas deferens) and is suggested to act both presynaptically and postsynaptically ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKFELDTTDGRARRGRLVFDRGVVETPAFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRDRFDSLGNKNALFGIIQGSVYEDLRDISVKGLVEIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKHKSDTSPLDAECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTKFYQRQGRPVPPLNVD",
    "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSARPGLLARAEARLTREWQRRGALAWALTPFACAFGAIAALRRAAYARGWKARVDCGVPVVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGVVSRGYGAKIVAPTAVTPASAPQQAGDEPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDDGLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLARPSRRKPLAQFAGERVLAAAGIGAPERFFATLRAAGVTPATRALPDHYAFATNPFVDDHFDAILITEKDAVKLGTSWRDARIWVVPVEAALDPRLIALVVEKLRGRTSA",
    "output": "Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTGGALLVAGTTSDAGKSMVVAGLCRLLARKGVRVAPFKAQNMSNNSAVTVDGGEIGRAQAMQARAAGLDPSVRFNPVLLKPGSDRTSQLVVRGRVTGTVSATDYITHRDRLADVVADELASLRAEFDVVLCEGAGSPAEINLRRTDLANMGLARRAHLPVIVVGDIDRGGVLAHLFGTVAVLHPDDQALIAGFVVNKFRGDPTLLAPGLDQLHDLTGRPTYGVIPYSDELWMDTEDSVSVVAGRTIGRPTPPRGADGLRVAAVRLPRISNSTDIEALACEPGVTVRWVTDPADVADADVVVLPGTKATVADLQWLRTAGLAEPIAAHAGAGRPLLGICGGFQMLCRHIDDAVESRAGRVDGLGLLDADIAFAAEKTLRHRTTPLQGYEIHHGQVTRCAADDWAGIGVRRDAVYGTHWHGLFDNDGFRRAWLADAAAAAGRSGFVVADDIDVSARRDAQLDVMADLLQNHLDLDAALGLVDAGPPPRPTISTGIT",
    "output": "Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDANTEHPAVGYGKLGVLLVNLGTPDGTDVTSMRRYLREFLSDRRVIEWSRLFWYPILYGIVLNTRPRKVGKAYELIWNKDLNESWLRTYTRNQAALMAEAFGGQPQVVVDWAMRYGQPSIASRIEALQKAGCERILVFPLYPQYAAATTATVNDKAFEALLKMRWQPALRTVPPYHDDPVYIDALATSINKHLATLDWEPELVLASFHGIPKSYFEKGDPYYCQCQKTARLLREKLGWPQDRLQVTFQSRFGPEEWLQPYTDATVERLAKEGVKRIAVINPGFVSDCLETLEEIAGQAAESFHHNGGEKFAHIPCLNDSPEGMAVLNHVVRRELEGWL",
    "output": "Catalyzes the ferrous insertion into protoporphyrin IX."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPLESGKLINDLRVSELKTELEKRGLSTQGVKVVLTVRLNKALRDEGLDPADHVFEHAVSPMKKSTRRSNEMARAAAAAAAEKVEKGAGDEGNDENVLVEEKEEEEEEEDSHDLQIIEDHELEVPSDEKDDTLVEDEEFEEAEQVEPEPEAVEPVVEEKPEEKLEEKPEEKLEEKPEEKPVEPEVVTVEEPVAEVIEVEKAVAEPVELKEKPEKEPEVVLVEEPVEQLENEPEVVPMEVEEAKKSDEQDGEDEFEEDDSSSDIEIIEPTLQESEPLAEEKVEKKEKKPEEIPHNLEQNEPISMETEEKVEEEVIILNSSINNVSQDDEIVLDYEEDLLEDPLDEPIEQKEPKAAEPTPKQLQKVEASTPQATPSKAASSSAGSGKSMLFGDDVKKTSIWIRGMTPATKASSVKQLASQYGKVIQSKIFNSKAADANGDVKNCFALIQFADVTAMELAMTSLHQKNYQGRVLRVEKVSESHLTSSAEKLAREKHVAEAASTMSTSPAPTPTPEPVVTTTTTTSAAPKRKEPIHAPESSSSEGQRAKRRAIEAPVRSRSRSRGGGGEPRSSRKPITFDREEESNRDSRRTIAAAPPARTSRMARSPLRAPLRAARGSESSRSSTRGGGGGGESLTISSRVDTSGCRGGAIKRSVERSVPNNISTSELRRKHHQIHVTVQQDAPRASYQTEQYARERSSSTTTSSRRRQVSPDRSEQRRHRDEPPPRRAPQEQPSRRRGASPPEPPRRQEGARRSEEPERRRLFDEREQLAHIMAAKDMYAEQQKIRAEKALIAFQMQQLEKKKLEAELQIAQKALLMQQAALGGGGALVVDGGALVAGGGAVGYHHQEHRSSYGGGGSSSNGGSSNRRRQTRRSPSPPQQHHSSSRRQRRDSGGAGRYRQSTSSSNSNRNSNSGGRNLVVTATTTNNTNATNAGRSYGIQSVPDASSYSTNNYQQRSSAASAYDLQITATMPQAGAANSGAAYHQPYGNVYQHNTAAYPVWGGLDAQGHMAMDTNWSQNAATPSTSTSSGGGGGQQWQQQSYGSNQHQHHQNNNSSQPSSSNRRGNDYGNYRGNY",
    "output": "Involved in pharyngeal muscle development and ensures pharyngeal grinder function during feeding . Plays a role in the defense against the accumulation of ingested live pathogenic bacteria in the intestine . Has a role in the determination of life span ."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQEDANGCINYEAFVKHIMSG",
    "output": "Regulatory light chain of myosin. Does not bind calcium."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTKQVEIFTDGSCLGNPGPGGYGAILRYRGHEKTFNEGYHLTTNNRMELMAAIVALEALKEDCDVVISTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWKRLDAALSHHTIKWEWVKGHAGHPENERCDELARAAAMNPIQEDVGYQPGS",
    "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MQGFISQVLGPVVDVDFNDYLPQINEAIVVNFESEGKKHKLVLEVAAHLGDNRVRTIAMDMTDGLVRGLKAEALGAPISVPVGEKVLGRIFNVTGDLIDEGEEISFDKKWAIHRDPPAFEDQSTKSEIFETGIKVVDLLAPYAKGGKVGLFGGAGVGKTVIIMELIHNVAFKHSGYSVFAGVGERTREGNDLYNEMKESNVLDKVALCYGQMNEPPGARNRIALTGLTMAEYFRDEMGLDVLMFIDNIFRFSQSGSEMSALLGRIPSAVGYQPTLASEMGKFQERITSTKKGSITSVQAVYVPADDLTDPAPATVFAHLDATTVLNRAIAEKGIYPAVDPLDSTSRMLDPNIIGEEHYKVARGVQSVLQKYKDLQDIIAILGMDELSEEDKLVVERARKIEKFLSQPFFVAEVFTGSPGKYISLEDTIAGFKGILEGKYDHLPENAFYMVGNIDEAIAKADKLKG",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSDINNNEPAENIEQPKQEPEDGNNSMSVDEQPETSSTNLPTGDNLAPMSVESPAHLNNEDSPKSDDSRERHGSNYVIEPHLELRDMAKDKTLENFLAQMDDYSPLIPDVLLDYYLSLSGFKCVDPRLKKLLGLTAQKFISDVAQDAYQYSKIRTGSSNASSTTFGAQNFGAGGASGIGSSGRRGDRGKTVLTVDDLSAALNEYGINLKRPDFFR",
    "output": "Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation), facilitation of DNA opening and initiation of transcription. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation (gcn5) and deubiquitination (ubp8). SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). SLIK is proposed to have partly overlapping functions with SAGA. It preferentially acetylates methylated histone H3 (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGQKINPTGFRLAVTKDWASKWFAKSTDFSTVLKQDIDVRNYLRQKLANASVGRVVIERPAKSARITIHSARPGVVIGKKGEDIEVLKRDLQVLMGVPVHVNIEEIRRPELDAQIIADGIAQQLEKRVQFRRAMKRAMQNAMRSGAKGIKIMTSGRLNGADIARSEWYREGRVPLHTLRANVDYATSEAHTTYGVLGLKVWVYTEGNIKSSKPEHESKQRKAGRRNAAAN",
    "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIEKTYQPSDIESRMSRVWEEAGAFKAGRPERREAEPFTIVIPPPNVTGSLHMGHALNNTLQDVLCRFERMRGRDVLWQPGTDHAGIATQMVVERQLMERKEPGRREMGRARFLERVWQWKAESGGVIVNQLKRLGASCDWSRERFTMDEGLSRAVAKVFVELHRAGLIYKDKRLVNWDPKLLTAISDLEVKQVEVKGSLWHLRYPIEGKAFDPSDPSTYIVVATTRPETMLGDTAVAVHPENAKLEYLIGSNVVLPLAGRIIPIVGDDYADPEKGTGAVKITPAHDFNDFEVGRRHHLPQISVLDREGRLTLSENEDFLRGLPSGALMLAEEFDGMDRFAARKAIVARLEEFGFLDKIEPHTHMVPHGDRSNAVVEPYLTDQWYVDAKELARPAMAAVRSGETAFVPKNWEKTYFEWMENIQPWCISRQLWWGHQIPAWYGPDGKVFVAETEDEAIGHALGYYVEQGVITAEQGAGMARDPAKRDGFITRDEDVLDTWFSSALWPFSTLGWPDETPEVRRYYPTNVLVTGFDIIFFWVARMMMMGIHFMKEAPFSTVYIHALVRDEKGAKMSKSKGNVIDPLNLVDKYGADALRFTLAAMAVQGRDIKLSPQRVEGYRNFATKFWNACRFAEMNDCVVPARFDPTAATETLNRWIVHETARTACEVTEAIESSRFNDAASAIYRFVWNVYCDWYLELAKPVILGEDSPAKSETRAMVAWARDEILKLLHPFMPFITEELWAVTAERTRLLTLTEWPNKADQTRKRRTLIAAADPFIGSEPITDLLEPYFRDDAAEAEIGWVVDLVTAIRSVRAEMNIPPATLAPLVLAGASDESRARAQRWSDVIKRMSRLADISFADQAPAGAVQLLIRGEVAALPLKGIVDVAAQRTRLGKEIAKADADIARVDLKLADQNFIANAPGEIVEDEKEKREAAAARKAKFVEALERLKAAE",
    "output": "Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTSYYSQDDNCAIGSEDTQFQKKNEREEPSNAELSGKSNSYLTISPEGNKIKDDYTVDVQDLETTKLSLPVVEALPTVDLHEESSSVVVGSETIENSSSSSTSERTPVSELDEVEKSGTLSIAKPGEVEQPEADCDAGEAPDADAPVEQPAFVSPPESLVGQHIENVSSSHGKEKVTKSEFESKVSVSEQDGGDPKSALNTSDTLKNESSDYTKPGETDPTSVTSPKDPEDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYVKMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATTEPKMTESTRVSTPVPSPEYVIKEVHTHDREPSTSDPPKESPIVQLVQEEEEEASPSTVTLLGSGEQEDESSSWFESETHILCSELTSICCISSFSEYIYKWCSVRIALYRQRSRTVSKGKDFVPPQPSLLLPVESVEVSVPQPPSGDVDSENMEREAETVDLDDLSSVHQGHLINHTVDTIELEPSYPQTLSQSLLLDVTPEMNSLSKVEGSESVKSEGGYIPSQLMTQESSVEFDDKTEKKTESFSSAEKLSVIYETSKVNEVMDNTVKEDILSTEVVTKFPETVVPPPMNTATVPEGESVETKPSIADTLKHTVTPVMDPSLPEVKEDEQSPEDALLRGLQRTATDFYAELQNSTDLGYGNGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIHLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVMSLVLCVVLGLMLCMQRCRTTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKTEKIETIKPADPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQTQKTKTEKRALKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI",
    "output": "Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGVFNYETETTSVIPAARLFKAFILEGDTLIPKVAPQAISSVENIEGNGGPGTIKKITFPEGSPFKYVKERVDEVDHANFKYSYSMIEGGALGDTLEKICNEIKIVATPDGGSILKISNKYHTKGDHEMKAEHMKAIKEKGEALLRAVESYLLAHSDAYN",
    "output": "May be a general steroid carrier protein."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MMVENWPAKPEGSQWTDDQWKAVVAHGRDILVAAAAGSGKTAVLVERIIKKIINEENPVDVDRLLVVTFTNAAAQEMKNRIGEALEKVLIEEPSSRHIRKQLSLLNKASISTIHSFCLQVIRSYYYMLDIDPRFRIANQTENELLKEEVLDDILEEEYGMEENQLFFELVDRYTSDRNDDDLQRMILALHTAAGAHPNPEKWLDRLVEAYNVEGKTIEDLMYASYLLEDVKFQLETATEHIRKAMELAMLPDGPAPRMETLQTDLVLLETLSHAARKSWTSVYEAMQHVSWQTLKRIKKSDYNEDIVKQVDSLRNKAKDEVKKLQEELFSRKPESFLRDFQEMHPVLGKLVQLVKEFSNRFQAIKRDKGMVDFTDLEHFCLQILSEQGEDGELRPSPVALQYRNRFAEVLVDEYQDTNFVQESIIKLVTKDSEQEGNLFMVGDVKQSIYRFRLAEPGLFLGKYKRFTQEGLEGGMKIDLAKNFRSRHEVLAGTNFIFKQIMGEEVGEIEYDADAELKLGASYPEGEDVAAELLCIHQSEEEVLDGEEGEEVEKAQLEARLIAQRIKAMVDSGYTVYDRKTNEMRQVQYRDFVILLRSMPWAPQIMEELKLQGIPVYAELATGYFEATEVNIMMNVFRVIDNPVQDIPLAAVLRSPIVGLNDEELAMLRAHAKKGSFYEVMRSFLRGAPLEGGKELHEKLKWFYHLLQGWREFARQQSLSDLIWKVYRETGYYDFVGGLPGGKQRQANLRVLYDRARQYEATSFRGLFRFLRFIERILERGDDMGTARALGEQEDVVRIMTIHKSKGLEFPVVFVAGLGRRFNTQDLMQRFLLHKDFGFGSQFIDPRKRIKYTTLSQLAIKRKMKRELIAEEMRVLYVALTRAKEKLILIGTVKDKEKEMEKWLDTREHTEWLLPDYVRASASCYLDWIAPSLYRHRDSEILLELGQGTIPNEIYEYDTSWKVEFVDGKTLLAPEPAQEEKQELLEALREKKAVPLESERKDEVYNRLTWKYEYEDATLQRAKQSVTEIKRNYQSEDGSDTAFIQKLRAPIRTRPRFMEKKGLTYAERGTAVHAVMQHVDLKQSITIESIQEQIAKMVNKEILTFEQAEEISVERIVAFFESHLGKRVLEAKSVEREVPFTMMLSAKEAYQNWQGKSEETILVQGVIDCMIEEDDGITLIDFKTDTIEGKFPGGFDQAKPILEERYKVQLSLYAKALEKTLQHPVKEKCLYFFDGNHVITIEE",
    "output": "The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAPQLLLCLILTFLWSLPEAESNVFLKSKVANRFLQRTKRSNSLFEEIRPGNIERECIEEKCSKEEAREVFEDNEKTETFWNVYVDGDQCSSNPCHYRGTCKDGIGSYTCTCLPNYEGKNCEKVLYQSCRVDNGNCWHFCKRVQSETQCSCAESYRLGVDGHSCVAEGDFSCGRNIKARNKREASLPDFVQSQKATLLKKSDNPSPDIRIVNGMDCKLGECPWQAVLINEKGEVFCGGTILSPIHVLTAAHCINQTKSVSVIVGEIDISRKETRRLLSVDKIYVHTKFVPPNYYYVHQNFDRVAYDYDIAIIRMKTPIQFSENVVPACLPTADFANEVLMKQDSGIVSGFGRIRFKEPTSNTLKVITVPYVDRHTCMLSSDFRITQNMFCAGYDTLPQDACQGDSGGPHITAYRDTHFITGIISWGEGCARKGKYGVYTKVSRFIPWIKKIMSLK",
    "output": "Snake prothrombin activator that attacks the hemostatic system of prey. This protein is functionally similar to blood coagulation factor Xa."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGRSYYVDDRVEKYFSKLVQQQKACITGLIIGQYSSQRDYAVLTAQTPQKEDQNEEKKPGLSKLEEIDDEWVSMHASQVGRMLPGGLMVLGVFLMTTPDLSKDAQTILRKLVFAVEKSSMKNRLWNFDEDDVSERVTLHICSSTKKITCRTYDINDPKSTPKPADWKYQNSVLSWLTVDCNVRVDVTIPLTSPSLTYQERQKSIRLGLVKWTKEIEDSVVLFNGQYKDKNGDLFEEQKKSSRSSSHYSPQIITANFLNASPLIDNTRSTALVQPCKSSLTIQGVMKCRGFIHSNRPKVKDAMQAIKRDLLNTIQDRCELLFEDMMLNGPSNENDACPLPQRVFVPINGSNLKLCDYLFGDETTSDLQSHFLEIMDQEVEQNELDFTEKKCELAHPEKRESEPASQHLESKPENKARSSSTSLLNKGLVISTIVASIAIIISFYYIM",
    "output": "May play a role in the trafficking of a subset of G-protein coupled receptors."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MVLAGRGMPGTKECLICLTALLLAAAAAAMINGVLDAKLDARMARLHRRVASLERIGAQRATVAAAGMLFAALALSITFLPRLTTALILLAIFSYTPLYTLWFKRRSPWGVVPGGIPGALPVLVGASAVSGTISSAPLILFLVMLLWQPPHFWALALKHQDDYRRAGVPTLPLVRGEAYTKVCIFVFAALLLPASLALWFTGACSARFAIEALCLGFFNLFSCYLYLVKNRRFQRAFQASIFYLLGLLSAVIIDICSRP",
    "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MSFHSFYQRASSLFKAYPSTSKILLLSTFSGGGGVLVYSDSNPLKRILHADATLDSDGNPIRKKKVVVLGSGWSGYSFLSYLNNPNYDVQVVSPRNFFLFTPLLPSVTNGTVEARSIVEPIRGLMRKKGFEYKEAECVKIDASNKKIHCRSKEGSSLKGTTEFDMDYDILILAVGAKPNTFNTPGVEEHAYFLKEAEDALNIRHSVIDCFERASLPNLTEEERKKILHFVVVGGGPTGVEFSAELHDFLVQDVAKIYPKVQEFTKITLLEAGDHILNMFDKRITAFAEEKFQRDGIDLKTGSMVVGVTADEISTKERETGKIVSEPYGMVVWSTGIGSRPVIKDFMQQIGQGQRRVLATDEWLRVEGCDGVYALGDTATINQRRVMEDIAAIFNKADKGNTGTLKKKDFNSVVKDICQRYPQVELYLKKNKLKNIANLLKSANGEDTQVNIEKFKQALSEVDSQMKNLPATAQVASQQGKYLAKCFNKMEKCEKKPEGPLRFRGEGRHRFQPFRYRHFGSFAPLGGEQTAAELPGDWVSIGHSSQWLWYSVYASKLVSWRTRMLVISDWTRRFVFGRDSSSI",
    "output": "Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane (By similarity). NAD(P)H dehydrogenase; more efficient on NADH."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSKISFDAQSISNSLRAAKHQPRKRFGQNFLHDRSVIREIVESIRLERDDNLIEIGPGMGALTEPLLAEVDAMTVVELDRDLADSLRIRIGANSHPNFTIIKDNAMHVDYRELYSEERGKLRVVGNLPYNISTPILFHLLSYADVIEDMHFMLQKEVVERITADVGSKTYGRLSVIMQYHCHTDYLLTVPRGAFNPPPKVTSAVFRLTPHIIKPVVAEDEEYFALVVRETFNHRRKTLRAIFKKSTLLPTLSEDDFAACAIDPQARPETLNVKDFVNLSNQARTIPV",
    "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVSFSSLALALSTVVGVLAAPGSEKYVELAKHQLTHSQTGTKNGYYYSFWTDNRGQVSYTNGKGGQYSVNWKDCGNFVAGKGWNPASAKTVTYSGNWKPSGNSYVSVYGWTQNPLIEFYIVESFGSYNPSTGATELGTVESDGGTYKIYKTKRVDAPSIEGKKTFDQFWSVRTSHRVGGTVTTKNHFNAWAKSGLKLGTFNYMILATEGYHSSGSATMTVS",
    "output": "Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRAFYGTELPNPLMLGTAQYPSPAILEQAFRASGAGVATVSLRRESGAGQTFWSMIRDLGVLILPNTAGCHTVKEAVTTAHMAREVFGTPWIKLELIGHTDSLQPDVFGLIEAARILTEDGFQVFPYTTDDLIVGERLLAAGCEVLMPWGAPIGSGRGLNNEYALRAMRAEFPDTPLVVDAGIGLPSHAARALELGYDAVLLNTAVARAGDPVEMARAMALAIQAGQLAHRADPIEARDMASASTPVIGKAFLS",
    "output": "Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MARPQPCGPPHARCGSPSLPERPLQVKVVGLFSCPNFQIAKSAAENLKNNHPSKFEDPILVPLQEFAWHQYLQEKKRELKNETWEYSSSVISFVNGQFLGDALDLQKWAHEVWDIVDIKPSALYDALTEDFSAKFLRDTKHDFVFLDICIDSSPIGRLIFELYCDVCPKTCKNFQVLCTGKAGFSQRGIRLHYKNSIFHRIVQNGWIQGGDIVYGKGDNGESIYGPTFEDENFSVPHNKRGVLGMANKGRHSNGSQFYITLQATPYLDRKFVAFGQLIEGTEVLKQLELVPTQNERPIHMCRITDSGDPYA",
    "output": "Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKEEFARILTAAEKIKSDSEVLVVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNLLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDNPRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL",
    "output": "Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGINKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH",
    "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKMDERKQQILLAIIKDYINTAEPVGSRTISRKYKLGVSPATIRNEMSDLEEMGYIEQPHTSAGRIPSNLGYRYYVDCLMQREQLSEEEEVTIRRGYENKVREVGEVLNRTGRMMAQLTHYTALVQMPSFRRSAYKHVQMVLMGPSQAILIVVMDTGAVHHQMMTVPESITQQDLDQISSVLNAKLQGRTMDNIRLTLIKEIYFELSKHRSILDLALELMQDRVISVAEDKIYLEGVFNILNQPEFHNVERVKILLSLLEQEDTLKDILDFTRDRQGITIKIGNENLRQEIQDCSMVTATYQVGDKILGTIGVLGPTRMDYARVVTVIDCMSRNLSRTLDRILKGQV",
    "output": "Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAEGRIIKALSGFYYVQSDNQQFVCKGRGLFRNKKITPLVGDYVEFEPKDDNEGYIMEIKERSNELVRPPIANIDQAIIVSSAVDPDFTTLLLDRFLVLIESKHIQPIILITKVDLLNEDQLENIKLYKQHYEKIGYRVELVSSKNQDLLPELEPYFDEKVSVFAGQSGVGKSSLINVLDPSLLLETAEISKSLGRGKHTTRHVELMKIGNGLVADTPGFSVLEFREIEAEELADSFPEFNARMHLCKFRGCMHDKEPKCAVKEAVENEEIAVFRYNHYLRFLEEIQTRKPRY",
    "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNSTEPDSARVTRTDRLDPPEIADVLTLARAAGDADGADPFDEHTLLRLRDPHAPAHHLTVRAADGILAGYAHLDSTDPAAGTGVELAVHPTYRRQGIGRALARAVRATVTGPLRAWAHGDHPSAAALAVDLGYRRARVLWQLRRPLSAPIPQPPLPEGVTLRAFRPGTDDDAWLALNARAFADHPEQGRWTSADLRARRDEPWFDAAGFLLAVDPAGHLRGFHWTKVHERPGSPRIGEVYVLGVDPQAHGGGLGKALTAAGLAYLRDRRGLDRVMLYVDESNTAAVALYERLGFARWSAHVNYQRS",
    "output": "Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPNRRGSRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWALLREEEKEKYSEMAREWKAAQGKDAGPWEKQKPVSTPLRRPAMLVPKQNVSPPDMSCLSLKSDQALLGGIFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINPGEIPRGFRFHCQAASDSSHKIPISHFESGHDQATVLQNLYRFIRPNSGKWPPIYCKSDDRARVNWCLKYMAKSSEITQDLELVTVEDLVVGIYQQKFLKEPSKTWVRSLLDVAMWDYSSNTRCKWHEENDILFCALAVCRKIAYCISNSLATLLGIQLTEAHVPLQDYETSNSVTPKMVVLDAGRYQKLRVESSGFSHFSSSNQEQRSNTPTGDYPSGVKISGQSSSVRGRGITRLLESISNSSSNIHKFSTCESSLSPYMSQKDGYKSFSSLS",
    "output": "Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVAPTALKKSDVSEGTVPVTTTSRIVGVDNTEKIDEDDDDADVLIDQDGDAMLVDEENNEESNKKKEDAGVVLDAEGKPRFTSAASSAQTKVKLESRKVSVPPHRMTPLKNNWSKIYPPLVDHLKLQVRMNLKTKSVELRTHPKHTTDPGALQKGADFIKAFTLGFDLDDSIALLRLDDLYIETFEIKDVKTLQGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMARESVVSLILGSPPGKVYGNLRTVASRLKERY",
    "output": "Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAYSYTEKKRIRKDFGKLPPVLDVPYLLAIQLESYRNFLQEGKSLAERGELGLHGAFKSVFPMVSFSGNAALEYVDYRLGKPVFDVKECQLRGVTYAAPLRVRVRLIIYDKESSNKAIKDIREQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLHSARIIPYRGSWLDFEFDPKDCVFVRIDRRRKLPATILLRALGYGTEQILDTFFDSTRFYLKRDGFEMDLVANRLRGETALFNIADANGELIVEEGRRITAKHIRVMEKSGLERLSVPLEYMLGKVTAKNLVHPATGELIAEANTELSVDLLEALVSSGITEVDTLYTNDLDNGPFISDTLRIDPTSNQLEALVEIYRMMRPGEPPTKESAEGLFQGLFFSEDRYDLSGVGRMKFNRRLGREEDTGAGVLDNDDIVAVLKTLLDIRNGNGMVDDIDHLGNRRVRSVGEMAENQFRVGLVRVERAVKERLSMAEADGLMPQDLLNAKPVAAAIKEFFGSSQLSQFMDQNNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHATHYGRVCPIETPEGPNIGLINSLSTYARTNSYGFLETPYRKIVDGKQTDETVYVSAIDEAKYVIAQASANVDAEGRLVDELVQVRHMHETTLIPKEKVNLMDVSPRQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLKADKPVVGTGMEKNVAKDSGVCIVANRGGVIESVDASRIVVRVNSEETIAGEAGVDIYNLTKYVRSNQNTCINQRTLVMKGERIASGDIMADGPSVDMGELALGQNMRIAFMPWNGFNFEDSILVSERVVEEDRFTSIHIQELTCVARDTKLGPEEITADIPNVGEGALSKLDQSGIVYIGAEVEPGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSQRVKTGTRGTVIDVQVFTRDGIEKDDRAKFIEKSQLDQVRKDLNEEFRIVEKATFERLAEALIGQQAEGGPGLARNAIITEEYLANLDHPEWFKIRVANEDASEQLEKAQAALIERRKELDAKFEDKKRKLQTGDDLAPGVLKIVKVYVAIKRRIQPGDKMAGRHGNKGVISKIMPVEDMPYDENGDPVDIVLNPLGVPSRMNVGQVLETHLGAASKGLGRKINEMLVVEREKAEAVAELRSFLGEIYNGYEGDLRCARTEDLDSFTDEEILTLASNLTGGVPMASGAFDGAKESEIKRMLRLAGINESGQVKLFNGRTGDAFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLVKEIRSLGIDIELENE",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MNHLNKLMERLGHQFNNLELLKIALTHCSSGADNNERLEFLGDSVLGFIIASELYQRRPQAREGDLSRMRASMVNGDELAQMSTKLGINEYLQLGVGEQKSGGKRRRSILADALEAIVGAIYIDAGLETCRRCVLNWYGERVDDLSKLSPKKDAKSLLQEWLQARRLPLPTYEVKITGEAHAQTFTVNCYVKGLPHKTEGVNTTRRRAEQIAAKRFLELLDDGKGDGITERDQ",
    "output": "Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MEIKEEGASEEGQHFLPAAQASDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLALSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHITTDVRGQKCALVCECTAPESVSSKGEKTLEFVPVNLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLHRFETERRNTGYQFIYYSPENTAKAKEVLSNINQLQPLVATHADLLLNSASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGVLKKPPSPKSSTEESSPQEQPPLMRRQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERDGGSEGSGSNNDGEKEPSLADSIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSNDVLPVVTGRREHYVVEVKLPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKALLENLHQNIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCRKYAFNMLQLMAFPKYYRPPEGTYGKADT",
    "output": "Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-bisphosphate (By similarity). Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles (By similarity). The lipid phosphatase activity is critical for tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MERPEPELIRQSWRAVSRSPLEHGTVLFARLFALEPDLLPLFQYNCRQFSSPEDCLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLASLGRKHRAVGVKLSSFSTVGESLLYMLEKCLGPAFTPATRAAWSQLYGAVVQAMSRGWDGE",
    "output": "Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSRRFAEYESLDLSRVNEEVLADWMQHRLFEESLKSREGAPSFVFYEGPPSANGMPGIHHVMARAIKDTICRYKTMKGFRVDRKAGWDTHGLPVELGVEKSLGITKEDIGKSISVEEYNAACRRDVMKFTKEWEDLTHKMGYWVDMEHPYITYDNRYIETLWWLLAELYKKGLLYKGYTIQPYSPAAGTGLSTHELNQPGCYRDVKDTTCVAQFKIMDPKPEMQLHGDAFFLAWTTTPWTLPSNTALCVGPEIEYLAVQTFNPYNGIPITVVLGKPLLHTLFNPKGECEEIPASYDPAQKLLPYKVIASWKGKELEGMRYEQLIPWVNPGEGAFRVITGDFVTTEDGTGIVHIAPTFGADDDRVAKKSGVPPLMLRDKEGNMRPMVDLAGRYFPTTDLDPVFVEKHMDLPLYDVYAGRYVKNAYDAGKTEKDETLDVELCVMLKMQNRVFRIEKMTHNYPHCWRTDKPVLYYPLDSWFIRTTACKEEMIANNGKIYWKPESTGTGRFGKWLENLQDWNLSRSRYWGTPLPIWRTEDGSEEICIGSVEELYNEIEKAVKAGMMERNPWAGFKPGVYTEENYAKIDLHRPFVDGITLCSPSGQPMRRELDLIDVWFDSGAMPYAQMHYPFENRERVEDGSVFPADFIAEGVDQTRGWFFTLHAIATMISGTSSFKVVVSNGLVLDKKGNKMSKRLGNAVDPFETIKKYGSDPLRWYMITNSSPWDNLKFDTDGVEEVRRKFFGTLYNTYQFFALYANLDGFTGEEESIPFAKRPEIDRWILSELNTLIREVDDQLSDYEPTRAGRAISDFVSENLSNWYVRLSRRRFWAGDMTEDKLSAYQTLYTSLLTVSKLMAPISPFYADRLYRDLTGKDESVHLALFPRPDQSQVDRALEQSMQMAQQISSMVLALRRRVNLKVRQPLATLMIPAIDDEQRRCIESVQPLILSEVNVKELRFVDDSMGILVKRIKPDFKRLGPRYGKVMKALAEAVTAMTQEEIRSLEKAGTFRMEVAGTPVELELADVEIVSEDIPGWLVANEGNLTVALDITVTDELRSEGLARELVNRVQNIRKQSGFEVSDKVDVLLLSNDIMDKVVAEHHDYIAQQIQAESLEISDAVSDGVELDFDDFVLSIQVVKHQG",
    "output": "Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIQMQTNLDVADNSGARRVMCIKVLGGSKRKYASIGDIIVVSIKEAIPRGRVKKGDVMKAVVVRTAKDIRRPDGSVIRFDTNAAVLIDNKKEPIGTRIFGPVPRELRAKNHMKIISLAPEVL",
    "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGQKVHPIGIRLGIVKEHTSVWYADGRTYADYLLADLNVREYLQDKLKSASVSRIDIHRPAQTARITIHTARPGIVIGKKGEDVEKLRQDLTKQMGVPVHINIEEIRKPELDGMLVAQSVAQQLERRVMFRRAMKRAVQNAMRIGAKGIKIQVSGRLGGAEIARTEWYREGRVPLHTLRADIDYATYEAHTTYGVIGVKVWIFKGEVIGGRQEELKPQAPAPRKKAAK",
    "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MAERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFEGEEA",
    "output": "RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MGSEPRFEPRPELIDLPVLQKFKLYATPSNFYLIGRDENKSFRRILKIDRRDQNELNLFEDPTRYTKDEMRELKRRMIVGNEESGGFKAITTCYGIIGFVRFLEPYYMLLITKRKKVGEICGHTVYGIAESQMIAIPHPSIQSKVAKSEAELRYKKLLSVVDLSKNFYFSYTYHLMYSLQKNIGNTERGNPHDNTMFVWNSFLTREIRKILQNSIWTVALIYGFFQQTKCSVSGEKFVFTIIARRSRHYAGTRYLRRGVNDIGRVANDVETEQIVSKVVPAGQKIPITSVVQVRGSIPLFWSQEASVFNPQPEIILNKKDANYEATQHHFQNLRQRYGNRIIILNLLKTVTGEKKHRETILRGEFAKTIRFINKGMDREHRLKAIHFDLSKHYKKGADGAFNHLCIFSRKSLELTDLFYCKAPSGVGAEEVIYDSFFNNPIPSQDEEASSPEKEDMKADIFLLQNGVLRTNCIDCLDRTNFAQYAHGLVSLGHQLRTLGISGPPVVDLNNPLAIELMDAYQKMGNTLAMQYGGSEAHSKMFCDLRGNWNMVMRQRDIFTAVRRYYSNAYQDSDKQNAINVFLGHFRPRLGRPALWELDSDQHNIGRSGSNLDIENMRPLIRRSFSDNIIMDCDLNLEELVRENSQPTYEGLNGGVSGTNLEFPFYETEPASLSFLSVMRNEELMRETGSGQMFQGSSSNSDSHRPNDIPGFSHSYVTKFTPAEDIFERGSSKSVSSDNLFTDRDESVTSLTNTNSSFEFPIMGGSDLLPGFSNAFARWVFSARAW",
    "output": "The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKEIAVTIDDKNVIASVSESFHGVAFDASLFSPKGLWSFVDITSPKLFKLLEGLSPGYFRVGGTFANWLFFDLDENNKWKDYWAFKDKTPETATITRRWLFRKQNNLKKETFDDLVKLTKGSKMRLLFDLNAEVRTGYEIGKKMTSTWDSSEAEKLFKYCVSKGYGDNIDWELGNEPDHTSAHNLTEKQVGEDFKALHKVLEKYPTLNKGSLVGPDVGWMGVSYVKGLADGAGDHVTAFTLHQYYFDGNTSDVSTYLDATYFKKLQQLFDKVKDVLKNSPHKDKPLWLGETSSGYNSGTKDVSDRYVSGFLTLDKLGLSAANNVKVVIRQTIYNGYYGLLDKNTLEPNPDYWLMHVHNSLVGNTVFKVDVSDPTNKARVYAQCTKTNSKHTQSRYYKGSLTIFALNVGDEDVTLKIDQYSGKKIYSYILTPEGGQLTSQKVLLNGKELKLVSDQLPELNADESKTSFTLSPKTFGFFVVSDANVEACKK",
    "output": "Hyaluronidase that mediates hydrolysis of (1->3)-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate. Very specific to hyaluronate: not able to hydrolyze chitin, heparin or chondroitin sulfate."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTLPPSCRWSGDHLELLDQRQLPGAVVFMQLRRWQQVAEAISSMAVRGAPAIGIAAAWGVVLAARSGDDLLTAFRGLRASRPTAVNLRWALNRMQAAMGSSASVDVEALTDAAAALQREDCVLTQRLVDHGVSLLAQGCRVLHHCHTGAIATGGVGTALGVIAAAHARGLLRHAWLDETRPRLQGAALSAWELGCLGVPCTVIVDGASGLLMRRGEVDAVMVGCDRVSANGDVANKIGTYNLALVARAHGIPFYVCAPGSSIDRATVDGEAITIEERDAEEITHVRGMDVAAPGAQVWNPAFDITPAHLVTGFITEFGVLRPPYREVLSELPLPNQL",
    "output": "Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIEIPTGLPAELVPLSWLLGVWEGSGVVEYAVGDETVRREFGQRISFSHDGLPHLNYSSYAWIEGDDGPVPFVTETGYWRLRRRVTDGDPGPAMLPPTDERPFTTAEEVETLCNADGGFDVEVALVHPGGVSELYVGQVKSARIDLATDAVLRTEGAKSYTGATRLYGFVERDLLWAWDIAALGQPLRTHASGRVSHVD",
    "output": "Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MANNAAACAERATNDMLIGPDWAINIELCDIINMEPSQAKEAVKVLKKRLGSKNSKVQILALYALETLSKNCGESVYQLIVDRDILPDMVKIVKKKPDLTVREKILSLLDTWQEAFGGSGGRFPQYYNAYNELRSAGIEFPPRTESSVPFFTPPQTQPIVAQATASDEDAAIQASLQSDDASALSMEEIQSAQGSVDVLTDMLGALDPSHPEGLKEELIVDLVEQCRTYQRRVMALVNTTSDEELMCQGLALNDNLQRVLQHHDDKAKGNSVPATAPTPIPLVSINHDDDDDESDDDFLQLAHRSKRESARGTGQGNFNPILPPPPSSMRPVHVDSGAMDFLSGDVYKPQETFENVKPPSTSQSSNHDYSAPIFDEPVPQSKSPEHALFTKPVYDQTEQLPPAPWETQEPRKYPPSMSARTNKRPEYFQHNVPQHSSSASESSYDDLLGQSRNLSLNPTASAAPVTPPKKDDKPEDILFKDLMDFAKTRTSSSSSSKPNNQNNKPF",
    "output": "Might contribute to the loading of the ESCRT machinery."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MGTARFLRAVLLLSVLLMVTFPALLSAEHHDGRVDICRLPSDSGDCLRFFEMRYFDGTTCTKFVYGGYGGNDNRFPTEKACMKRCAKA",
    "output": "Serine protease inhibitor that inhibits chymotrypsin and blocks voltage-gated potassium channels (Kv)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MENNTASSPYTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSDVENIIKYHGSYLVGTNLWIIMDYCHGGSVRTLMEAGPISEPCISLILRETLQALKFIHHAGIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRKRITFIGTPYWMAPEVIRDGQEYNVMADIWSLGITAYEIATGSPPHAKEDPFRAVYLIAHTAPPRLNGNFSALLKEFIASCLQDVPQRRLDSSELLKSKFIKQYSRMSISELTNVVKRYDTWQAAGGIPQTLLLGEEADDGSDPDQETSDTAASDDGWEFGTIKQGQSNVSSITGTSTSTTTAATSSTTVTGTVIPKSSTVHEPPSSNDSHPLLQLFKDSKISDDDSPSNAEGASTEDSKGEVSYSQIELPSLDSSNLSSKKSTIQSKHTKQAEDYDLFVGRTRSNSKTSSDQSIKRPLPRVVQRQKTSLGKRGISMSPMKPGLRMPSSFDLQSRSISMGAFEQLSTPLEAPAHKHSAVLQPLEVNRSISIPPPKSISPSILHKPSLESASSTPKISSCSSTPKPFNSKLRAHLPPLSIGSPAVQPLANDNYDSLGVRGLNMELFNDYPGNMHNIKSVLSLEIDIVLGEMDACLKSLECNLLNRKAYNE",
    "output": "Has a role in the regulation of cell polarity, growth and division."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVESSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSPDPPSASTVTPDSAILGVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRVRKLDKGTNISDEDFLLLELLHWFKEEFFHWVNNILCSKCGGQTRSRDRSLLPNDDELKWGAKKVEDHYCDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARRTKVKEALLRETINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKETSFIPSENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKIDSISIRTTSQTFQTGTIEWKLRSDTARVELTGDNNLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL",
    "output": "Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins (By similarity)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MKNISLLGASGSIGTQTLDVLRSHPDQFRLVAFSVGKNIDYAVKVIQEFSPQIVSVQREEDVLKLQAVSGNTKIVYGSEGLLEVALHPDAEIVVNAVVGSVGLLPTLRAIEAKKTIGIANKETLVTAGHLVMEAARKHNVSLLPVDSEHSAIFQCLNGENEKRISRLIITASGGSFRDKTRDELHHVTVEDALRHPNWSMGSKITIDSATMMNKGLEVIEAHWLFGIPYEQIDVVLHKESIIHSMVEFEDRSVMAQLGSPDMRVPIQYALTYPDRLPLSDTKQLNLWEMGTLHFEKMNQERFRCLRFAYEAGKTGGSMPAVMNAANEVAVEAFLQKRIGFLTVEDLIEKAMNHHNVIARPSLEEILEIDATTRRFVMEQI",
    "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDKDWFEVSVITSSEAVEAVTGILYNTPVKGVAIEDSKDVEFKKKHPGDWDYFDESLLNVKDGAVIKAYYKDDHNFDESVKYIEESIDKLSEFGINKGEGKVFVNKVNETDWENNWKKYYKPTKIGARIVVKPLWEEYTPKDYELMLNMDPGMAFGTGTHETTRMCIQALERYVNEDAEVFDIGTGSGILAIAAAKLNAKKVLGVDLDSVAVKAAKENIQYNNVNNIEILHGNLMEVVQGKADIIVANIIADVINILIPDINKFLKTDGYFISSGIIKDRAEDVIENLKKNKFEIIEVNNQGEWICIVAKL",
    "output": "Methylates ribosomal protein L11."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSPKTETKASVGFKAGVKDYRLTYYTPEYETLATDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTSEEMMKRAVCARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEVIREASKWSPELAAACEVWKEIKFEFEAMDVL",
    "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTNIRKTHPLMKIINHSFIDLPAPSNISSWWNFGSLLGICLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYLFLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVQWIWGGFSVDKATLTRFFAFHFILPFIVAALAGVHLLFLHETGSNNPSGLSSDADKIPFHPYYTIKDILGVLFLFLILTSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILVLALIPLLHTSKQRSMMFRPFSQCLFWILVADLITLTWIGGQPVEHPFIIIGQLASILYFLLILVLMPITSVLENNLLKW",
    "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MASALLCFLAAILPGMIAAQNTWVLGTSDVRTVEPVNPVGGGVSLGGIDIDSTENRIIVQNTGIAVPFGREKAIDPNSELVINVQAGDSCSIKVLPRQSDPLSQIPGRLVPPSFPCDFSPGEVKYVHFGSRKPQTDKVKLQLRYDTATDVYIIPFTIDVRVESKQLEIVTRNVPLVVQDLMGTSDALDADKLEFEFDSNTEVCKVTVLSSTSGLPRYGEVMNHDEQGQMIDCNDFLELGIQYRHTAATSSPREDYIPLVVELQNQQGQVIKQEYFQSMVRIIDGDDNTPPSLVLSSDMMMEVDQFVMTAITPSILAAEDVETPADMLIFNITSQTLGPDDGMIVSTDDRNQPITSFTQKDLRDLKIAYKPPPRDTDVQTIYQIELEIVDSELATSETHSLLIVVKPKNTLAPVVTTNTGLVLFEGQSRPLLGGQNLGISDEDNLQDVIIAPINGSRYGELRIGNQRIKQFTIADLIEGAVTYHHYGTDTYSDNIIFRMTDGQHEVEFLFPITIAPIDDEAPIVDVNTGVTVNENEVVAITNFVLSATDIDSDDSEIRFVLEQPLSDMGNLFLRQVNIPEDPQNWISQDNFYEREVTEFTLEDIQNGHLFYQHGGSHNADPVFDRILFRVVDSADPQPNESPVQELLVKVMPQDLQPPEMFGGTTLQLSVDEFQITPILKKNLRFTDMDSNDRELKYTIVSPLTDSDSNNNLPVGDIVLTDEPNTPINMFTQAQINHMKVSYKPPSTELGIAPRAITFQFVVQDTQGNMGSPHNFIILLRPVDNQPPTITNTGVQVFERGTVIIDQTMLDATDPDTDRNSIRVVLVQPPVFGTMNLNDIALEKGDEFTLGDIENSRVKYVSGDAEEQSDEIHLEITDGVHVVPIVIHINVAPIDDEAPTLDLPPGTIGSFLEVQENSFSLITSNILSASDPDTEDLLLTFIVDRQPNEGRIESNGVVADVFTQQDIVNGLVRYVHTGGEIGPSKRDDSFNLTLSDMSPDWILGGNEITQVEVYVTVLPVDNLAPNVTMGVQFYVDEAGKGNINMTHLQAPDVDTEDDDILCTIVVAPSVGYLENISPAPGSEKSRGGMPISAFSIKDLRLNHINYVQSIHQGMEPEEDQFTFRCTDGVNESPNFLFPINIIPVNDEEPQVYAREIIVDEGGQRIIDEPLLRAEDGDVPADELHFFIVTPPQHGTITYTRLEGDIPILNFTMDQIANGNDIKYIHDDSETTEDSFTVLLTDGKYEITKEITITILEVDDETPRLTINDGIDIEIGESRIISNRILKATDLDSADSNLTYTVRYAPEKGLLQRLSKFDGSVVENITLGMNFTQWEVDNQRIRYVHTDGDGGRDLIKFDITDGTNPLIDRYFYVTVDHIDNVHPSIINAGVTMQEGSRVTLTTSIISTSDLNSPDEDLLFTITTAPTKGHLESTDNPGMPINSFTQLDLAGSKIYYVHTADDEVKMDSFQFQVTDGFNTVVRTFRISFTDVDNKEPVVRYDTIRLQEGDNKLITPFELGIDDRDTPANELRFTITQLPIHGNILRNNTALVTEFTMHDINENLISYQHDGSEQTADSFSFIVTDGTHNEFYVLPDITTLTRQPQQVPIEIVPVDNGAPQIVVNRGAPTLDLLGTGELGFMITNKYLMSEDRDSVDNSLLYVITTQPQHGYIMNIALGNISITNFTQSDVNNMYIQYIVYPNVDATSDTFFVEVRDAGGNTLPNQPFRLNWSWISLEKEYYEVNETERYLNIKLVRRGYLGETSFVGIQTADGTAIADEDFRGKSARQVQFNPGQTEGFWRVRILNDRLYEQAEVFEIILHDPVMGALEYPDRAVVTIFDAEDESGVFIDLPDNYVIEEDIGEFLVPIRRTGDLSQELMASCSTMPGSATGSDPSPVLSFSDYISRMEEDPDNMVAFDKGEDLAYCRILIIDDSLYEEDETFQVKLSNPMGGRIGNPSAINVIIAGDTDDVPSFYFGEPEYKVDENAPFVEVTVFRTGTDVSKMASVTVRSRASNPVSAVAGEDYAGISRNLDFAPGVNQQTVKVYIIDDRGQPRLEGPETFELVLNMPMNGVLGAPSKTVITINDTISDLPKVEFRHPTYEVNENDIRITAEVVRSGDLSIESSVRCYTRQGSAQVMMDYDERPNTEASIITFLPGERSKTCTVLLMDDNVFEPDEAFRLVLGSPRTASGVPAVVGEQNVTVVTVHDVGDAPIIKFPETKFSIDEPTDLDSVVTVSIPVIRMGDNTQTSIVRVFTKDGSARSGIDYNPLSQVLEFGFNVTERVVEIEILPDEDRNEMREAFTLHITNDQMMIADVQMNHAIIYIEQEGQASGVTFPSQPVVVSLLDYDDIPNARTNPPRGYPLICVSPCNPKYPDFATTGPICDSEGLNDTVTQFRWMVSAPTSESGVTSPLRQTDSDTFFSSTKSITLDSVYFGPGSRVQCVARAVGSEGDAGREHPSNSIVISTTDGMCMPRVANAIGAEPFTARMRYTGPADPDYPNKVRLTVTMPHVDGMLPVISTRQLSNFELALSKDGYRVGTHRCSNLLDYNEIPTDFGFITEETKNPNVVGDTYAYQYSPELRGEETLRFYRNLNLEACLWEFNAYYDMSELLDECGGLVGTDGQVLDLVQSYVSMRIPLFVSFVFHSPVATGGWKHFDQQSTLQLTFVYDTSILWQNGIGSQVTTGTQSLQGNLYPTSMRIDEDGRLVVNFRTEALFNGLFVQSHQSTDVVSTVNSIDHPGITYSLSLLRTEPTYAQPEQLWQFVSDLSVSDYSGTYTIQLVPCTTLPNTVYSQPPVCNPEDIITFELPIRFQQVSDPVPEEYSLNTEFVLVGKESIYLSDGSMGFGEGSDVAYNPGDTIFGRIHVDPVQNLGAGFNLDIQKVFLCTGRDGYIPKYNPAANEYGCVADTPNLLYAFKILDRGAPDTIVREFNGLPFNATLAIDNAADLELVQQPGADGFRLASDALFEVDYGRTWYLHSIYSMRSSESSGIGKRETEHHAISSRQRRQANSEALVDPAQGQGTNMKRVALQGPQDVDNNLGGTYELAPKGTNVVMIAVVIGVILIILLVALVIGVVVRRRQAKQQPVVVVNGSAKVVSNVHFDDNTEV",
    "output": "Extracellular matrix protein that may serve as substrate for the migratory primary mesenchyme cells (PMCs), the interaction possibly providing guidance information to migrating PMCs."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MFEGPVQDLIDELGKLPGIGPKSAQRIAFHLLSVEPPDIDRLTAVLARVRDGVRFCAVCGNVSDDERCRICSDPRRDASVVCVVEEPKDVQAVERTREFRGRYHVLGGALDPLSGVGPDQLRIRELLSRIGERVDDVDITEVIIATDPNTEGEATATYLVRMLRDIPGLTVTRIASGLPMGGDLEFADELTLGRALAGRRAMV",
    "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MMVSLFSQFDSPWLLNIPLVLLALIMPWKLFVSFGPSWAGTRSSRLVYVTMETLMSQVMQPLNKLGFRWVVLFSSLMLMLMTLNVIGLFPYTFTPTTQLSMNLGLAVPLWFGTVVYGFRNHPVIALAHLCPEGAPNLLVPVLVVVETLSILMRPLALGLRLTANLTAGHLLMHLISSAVLGLMELSVMLSGITLLLLVFLTMLEIAVALIQGYVFAILVTLYLDENL",
    "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MRRAIVRGTGHYLPERVVENSWFEDKLDTSDEWIRARTGIERRHFAAEDQRTSDLGILAAQAALADAGLEAAQIDAVIVATSTPDLTFPSVATMVQAGLGMRHGFAYDLQAVCAGFVYALANADALIRAGLADRVLLIGAETFSRIMDWTDRGTCVLFGDGAGAVVLEAAEGQGSSADRGILATDLNSDGQYRDLLYVDGGVASTGTAGHLRMQGNLVFRHAVEKLADTAHRALDRAGLTPDQVDWLVPHQANLRIIEATAKRMHLPMEKVVLTVADHGNTSAASIPLALSVANAEGRFKPGDLLVAEAIGGGLAWGSVVLRW",
    "output": "Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSQAPEARPSPPSVYHERQRLELCAVHALNNVLQEQLFSQEAADEICKRLAPDSRLNPHRSLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGLLSLPLRRRHWVALRQVDGIYYNLDSKLRAPEALGDEDGVRTFLAAALAQGLCEVLLVVTKEVEEAGCWLNTS",
    "output": "Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme (By similarity)."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "SGSKTAKIGDGCFGVRLDRIGSTSGMGCGGVPKPTPGGS",
    "output": "Snake venom natriuretic peptide that exhibits hypotensive and vasodepressor activity. Acts by activating natriuretic receptors (NPR1 and/or NPR2 and/or NPR3) (By similarity)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MSAFCLGLVGRASAPAEPDSACCMELPAAAGDAVRSPAAAAALIFPGGSGELELALEEELALLAAGERPSDPGEHPQAEPGSLAEGAGPQPPPSQDPELLSVIRQKEKDLVLAARLGKALLERNQDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENREGEWEGRVSELESDVKQLQDELERQQIHLREADREKSRAVQELSEQNQRLLDQLSRASEVERQLSMQVHALREDFREKNSSTNQHIIRLESLQAEIKMLSDRKRELEHRLSATLEENDLLQGTVEELQDRVLILERQGHDKDLQLHQSQLELQEVRLSCRQLQVKVEELTEERSLQSSAATSTSLLSEIEQSMEAEELEQEREQLRLQLWEAYCQVRYLCSHLRGNDSADSAVSTDSSMDESSETSSAKDVPAGSLRTALNELKRLIQSIVDGMEPTVTLLSVEMTALKEERDRLRVTSEDKEPKEQLQKAIRDRDEAIAKKNAVELELAKCRMDMMSLNSQLLDAIQQKLNLSQQLEAWQDDMHRVIDRQLMDTHLKERSQPAAALCRGHSAGRGDEPSIAEGKRLFSFFRKI",
    "output": "Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Predominantly recruits 2 dyneins, which increases both the force and speed of the microtubule motor. Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRTEDDSWDVTTSVGSTGLLVAAARALETQKADPLAIDPYAEVFCRAAGGEWADVLDGKLPDHYLTTGDFGEHFVNFQGARTRYFDEYFSRATAAGMKQVVILAAGLDSRAFRLQWPIGTTIFELDRPQVLDFKNAVLADYHIRPRAQRRSVAVDLRDEWQIALCNNGFDANRPSAWIAEGLLVYLSAEAQQRLFIGIDTLASPGSHVAVEEATPLDPCEFAAKLERERAANAQGDPRRFFQMVYNERWARATEWFDERGWRATATPLAEYLRRVGRAVPEADTEAAPMVTAITFVSAVRTGLVADPARTSPSSTSIGFKRFEAD",
    "output": "Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MDIGGPTNIRHVAHVTFDRFDGFLGLPSEFEPDVPRKAPSASATVFGVSTESMQLSYDSRGNCVPVILLLLQSRLYDQGGLQAEGVFRITGENSEEEFVREQLNKGIIPDGIDVHCLAGLIKAWFRELPRGVLDPLPSEQVMQCESDEDFVKVVRLLPQTEASLLNWAINLMADVIQFEHVNKMNSRNLALVFAPNMSQMADPLTALMYAVQVMKLLKSLTEKTVREREASSSVVDRRCSKEAEDGEKEKDNEEEEEDEEEEEEEEDEDEDEEEEGDGVYIIKEEEASEIIKVVADEHKSGSIKSEFEGSSATDSKGDNGVVQPPICSSNP",
    "output": "Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MRNLLENIKKNSQKLLNLTPKDKEKIILKLAQILRENFKIILEANKKDMANFTKSGAMKDRLLLDEKRILALCEGLEKIAYIEDPIGKISKGWKNYAGLSIQKMSIPLGLICVIYEARPSLSAEIAALMIKSSNACVFKGGSEAKFTNEAIFTLVNKVLKEFDLQDCFAMFTQRDEILQILAFDDLIDVIIPRGSSNMIQEIANNTKIPLIKQNKGLCHAFVDQSANLDMALKIILNAKCQRVSVCNALETLLIHEKIAKNFISLLIPEFKKFKVKIHAHENALAYFNNSNLKIFKANENTFDTEWLDFALSVKLVKDCDEAIEHINKHSSLHSETIISNDASNIAKFQRLINSSCIYANASTRFSDGGEFGFGGEVGISTSKLHARGPMGIEDICTYKYIINGEGQIRE",
    "output": "Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAQSSPPQSLQGLVPLGLLPGLGLGSAIGLHVSGLVLRFVRFLPFYATRRPSQPAGPARSTRTTQATAPRRTRPAPAGGQRQSASEREKLRMRTLARALQELRRFLPPSVAPAGQSLTKIETLRLAIRYIGHLSALLGLSEDSLRRRRRRSADAAFSHRCPQCPDGGSPSQAQMLGPSLGSAMSSGVSWGCPPACPGPLISPENLGNRISNVDPRVTPPYCPQIQSPLHQSLERAADSSPWAPPQACPGMQMSPEPRNKTGHWTQSTEPAELTKVYQSLSVSPEPRLSLGSPLLLPRPSCQRLQPQPQPQPQWGCWGHDAEVLSTSEDQGSSPALQLPVASPTPSSGLQLSGCPELWQEDLEGPPLNIFY",
    "output": "Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. May play a role with Tcf15 in the differentiation of myotomal and sclerotomal cells by regulating Pax family genes. Controls also the expression of the protocadherin PCDH8/PAPC, EPHA4, RIPPLY2, NOTCH2, FGFR1, and CER1. Binds to the E-boxes within the EPH4A and RIPPLY2 enhancers."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MTRSSVLADALNAINNAEKTGKRQVLLRPSSKVIIKFLQVMQKHGYIGEFEYIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGYVILTTSAGIMDHEEARRKHVSGKILGFVY",
    "output": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSSTPSNQNIIPLIKKESIVSLFEKGTRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGTKLEIDKPYEDTPNQGNLIVNVELLPLAYETFEPGPPDENAIELARVVDRSLRDSKALDLTKLVIEPGKSVWTVWLDVYVLDYGGNVLDACTLASVAALHNTKVYKVEQDSNGFRVNKNEVVGKLPLNHPVVTVSIAKVDKYLIVDPDLDEESIMDTKVSFSYTPDLKIVGIQKSGKGSMSLQDIDQAENTARLVAVKLLEELKKQLGI",
    "output": "Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKTLLLTLVVVTIVCLDLGYTLKCNKLIPIASKTCPAGKNLCYKMFMMSDLTIPVKRGCIDVCPKNSLLVKYVCCNTDRCN",
    "output": "Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities on many other cells, including red blood cells. Interaction with sulfatides in the cell membrane induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It targets the mitochondrial membrane and induces mitochondrial swelling and fragmentation (By similarity). It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity and inhibits protein kinases C . It also binds with high affinity to heparin . It also causes skeletal muscle necrosis after intramuscular injection into mice ."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSYYGNGGYNPYGAYGNVPPPVYGTPGLAPPTVHVHTDGGHHHGHHHHHHSFLHELGHALTGHHHHHHGHHFGHHHHHHHGHH",
    "output": "Plays a role in the stress response to heavy metals such as copper, probably in a fos-1/kgb-1-dependent manner."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MIKLKVKKGDEVVVITGKHKGKKGKILKVFPEDSKVIVFGVNLVKKHTKSNQMSEGGIITKELPIHISNIAHIDPKTGNPTKVAFKFLEDGSKVRVAKKSGEIIGKEGK",
    "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MVVSADCRISLSAPSCIRSSSTGLTRHIKLGSFCNGELMGKKLNLSQLPNIRLRSSTNFSQKRILMSLNSVAGESKVQELETEKRDPRTVASIILGGGAGTRLFPLTKRRAKPAVPIGGAYRLIDVPMSNCINSGINKVYILTQYNSASLNRHLARAYNSNGLGFGDGYVEVLAATQTPGESGKRWFQGTADAVRQFHWLFEDARSKDIEDVLILSGDHLYRMDYMDFIQDHRQSGADISISCIPIDDRRASDFGLMKIDDKGRVISFSEKPKGDDLKAMAVDTTILGLSKEEAEKKPYIASMGVYVFKKEILLNLLRWRFPTANDFGSEIIPFSAKEFYVNAYLFNDYWEDIGTIRSFFEANLALTEHPGAFSFYDAAKPIYTSRRNLPPSKIDNSKLIDSIISHGSFLTNCLIEHSIVGIRSRVGSNVQLKDTVMLGADYYETEAEVAALLAEGNVPIGIGENTKIQECIIDKNARVGKNVIIANSEGIQEADRSSDGFYIRSGITVILKNSVIKDGVVI",
    "output": "This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MKKLFGLLGHPVGHSLSPLMHNQMFQLLDFDGYYHAFDVEPSQLEKAVEGARALQMQGFNVTIPHKVTIMDYLDMVDEEAQEIGAVNTVVMKDGQLFGSNTDGQGYLESLMDVVTTPFPTQDVLIIGAGGAARAIGTVLKREKVRSITIANRTLAKAEEFSGVLESSETSCSALSLKEAEQQLERFSVIINTTSVGMSPRVDDMPLSLERLSRETVVSDLIYNPLETKFLREAKQKGAKTVDGLGMFVNQGALAFELWTGLRPDREKMRRCVLEQLGG",
    "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MKTLYSLRRFYHVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGVGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICIFGGIWHILTKPFAWARRALVWSGEAYLSYSLAALSVCGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLSTSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN",
    "output": "One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MADSMETHKFKVIIVGGSIAGLTLAHSLSKANIDHIVIEKRAEIAPQEGAFIGVWPNGAQILDQLGLYQSLEELTAPISRMHLSFPDDYSFSSFLPKTIHERFKYPIVSLDRQKVLEILFQNYPDKSNIITNQRVSEVRLLGDSASVVTEDGSVFRGDLIVGADGVHSPLTVEYACVFGISRPIPGLRSGEHINHYGDKFCVITFHGKDGRVFWFIIQKLDRVYTYPNAPRYSPNDAADLCGKMQNVVIWQDITVGDLWKTKVVASMTALEEGIFETWSLNRIVILGDSVHKMTPNIGQGANTAIEDVAVLASLINRMIHADDLNKPSESCIETMLQEYKSLRYEPAKSTYQRSRFGARFHTRDSWLKAVVGRYVFQYVGGLIENRTIKTLAGGDTIDFLPRPDRLETGRVAQFQKSEESPQRQWTLLWVSSLALFLFFPWLGSYLHSTIS",
    "output": "FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of andrastins, meroterpenoid compounds that exhibit inhibitory activity against ras farnesyltransferase, suggesting that they could be promising leads for antitumor agents (Ref.2). The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase adrD via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Ref.2). DMAO is then converted to farnesyl-DMAO by the prenyltransferase adrG (Ref.2). The methyltransferase adrK catalyzes the methylation of the carboxyl group of farnesyl-DMAO to farnesyl-DMAO methyl ester which is further converted to epoxyfarnesyl-DMAO methyl ester by the FAD-dependent monooxygenase adrH (Ref.2). The terpene cyclase adrI then catalyzes the carbon skeletal rearrangement to generate the andrastin E, the first compound in the pathway having the andrastin scaffold, with the tetracyclic ring system (Ref.2). The post-cyclization tailoring enzymes adrF, adrE, adrJ, and adrA, are involved in the conversion of andrastin E into andrastin A. The short chain dehydrogenase adrF is responsible for the oxidation of the C-3 a hydroxyl group of andrastin E to yield the corresponding ketone, andrastin D. The ketoreductase adrE stereoselectively reduces the carbonyl moiety to reverse the stereochemistry of the C-3 position to yield andrastin F. The acetyltransferase adrJ is the acetyltransferase that attaches the acetyl group to the C-3 hydroxyl group of andrastin F to yield andrastin C. Finally, the cytochrome P450 monooxygenase adrA catalyzes two sequential oxidation reactions of the C-23 methyl group, to generate the corresponding alcohol andrastin B, and aldehyde andrastin A (Ref.2)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARIAGVNIPDNKHAVISLTYIFGIGRHTAKNILAAVGITETTKIRELDDAQLDAIRAEVAKVPTEGDLRREISMNIKRLMDLGCYRGLRHRRSLPVRGQRTKTNARTRKGPRKPIKK",
    "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTNIFNAMRVTATVGGKEIVFETGRLANQADGAVWIQCGGTVVLVTACSQATDRDLGFFPLTVEYSEKMYAAGRIPGSFFRREIGRPSERETLVSRLIDRPIRPLFPKGLKDEVQVLANVISSDQNNDSDVLAVTGASTALGLSSIPFDGPVAGARIGRIDGQFVINPTIKEMERSDLNIVLAASRDAVVMVEGEASFVPEAVIVEALEWGHKEIQPLIDAQLKLREMAGKAKREFTAPVEDADLAARVAALATADLDVALRIPEKMARKDARKAVKEKVMEALVADPAYAEDTTPLRAVGDILSALEKRIVRERIVREGRRIDGRDTTTVRPILIEAGILPRAHGSALFARGETKSLVVATLGSSTDEQRMDSLTGDVTKRFMLHYNFAPYCVGEVKPVRVSRREIGHGALAEKALRPILPLGEDFPFTLRVVAETMESNGSSSMAAVCGGCLSLMDAGVPITAPVAGVAMGLIKEGDQYVVLTDILGDEDALGDMDFKIAGTSEGITAVQMDIKVKGLPTDVMARAMQQARDARLHILGEMGKVLEAPRAELSAYAPQHAEVFVNPDIIRIIIGPGGKNIKAITATTGASIDIEDSGRVSIFAPTLEAMEMAREMVQYYDQRADIGKNYTGKVRKVLEIGAIVEILPNLEALVHISQLDTNRVEQASDVARLGEDMVVKVIEINGDRIRASRKAVLLEEQGIEWKPEDTARPSGPREGGRRDGGRDGRRDGGRDGRRDGGRDGGRRDGGRRDGGRDRN",
    "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MDTQIAITGVAVGKEINNDNSKTDQKVSLPKADVPCIDKATQTIIEGCSKDDPRLSYPTKLETTEKGKTKRNSFACVCCHSLKQKCEPSDVNDIYRKPCRRCLKHKKLCKFDLSKRTRKRKPRSRSPTPFESPMVNVSTKSKGPTDSEESSLKDGTSYLASFPSDPNAKQFPNSRTVLPGLQQSLSDLWSTLSQPPSYGAREAETTSTGEITTNNHTKSNGSVPTNPAVLASNDEHTNISDAPVIYSTYNSPVPISSAPTSINSEALFKHRPKIVGDEETQNVKVKRQKKSYSRHMTRSFRKQLQSLIISQKGKIRDISMKLDTWSKQWNDLVEKSMFLPTIADPVSVGIISHEEATLRLHLYKTEISYLSKLPFIKVEENVSVDELRKKKPILFSVIMSCVSIVLTPKQTTRGTIMKLDSFVLNLITNQIFKANNKSIEIIESLSTLCLWYNFFEWSSKTRYHIFNYICCCLTRDLGPTYVNRSFGMFSDEDPKRFKSPLELYSNGASLTLLVYISALNISIFLRQSIQARWSHVTEKACEDLVKETKKSRHYDNDKLLLDSADDPILVQFAKMNHVLENIHTHLHERDLNDDEFDDPIFTKKYLNKLMEKYHKQLQEIFTKLDRNRPRVIAFYYSVEAYLYQYKLAVFIGEMSHTINEKVELPREIMDDFVKCYHCCKSALEEFSKLEPILITSLPLFHTSRIIYTVGMLLLKLRYSVVAIPSFHDLMPLTDDAIALVIGVNNLLEKTSELYPFNNSLYKFRYVIALFCQTYANKVIDVADRYNAEREKLKEKQVIDEVSNGHDGTKPINAYVTESQKMPTEEDPIIDNNTNQNITAVPDEMLPVYSRVRDDTAAMNLNINSTSYMNESPHEHRESMTGTTLLPPPFISNDVTNSADSTNIKPSPSSSVDNLNDYLTDINSLAWGVNSLNDEFWTDLFMNDI",
    "output": "transcription factor which binds to a weak acid response element (WARE) to mediate stress induction of PDR12 and FUN34, encoding an acid transporter and a putative ammonia transporter, respectively."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTTNDTWFTEHFQTTGSAIGFRVTGKLDEVQSPFQKIEIYNSTDWGKLMVIDGALMLTSRDNFLYHEMISHPALFTHTAPKCVVIIGGGDCGTLREVLKHPDIEQVTQCDIDEQVTRMAEKHFPELCTSNNDPRATLLFSDGVAYMADCPTNSVDVIIVDSTDPVGPAKGLFNRTFYESCFRALKNDGLLIQQSESPLALLELIKEMRHEMSKAGFKAFKTLPFPQPCYPTGWWSVTLSSKQPNANFAFRQTDAQTKPFDTLYYNAHLHHGVLVPPPFIAHALGE",
    "output": "Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS",
    "output": "May be involved in sperm differentiation and proliferation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEVVTFGDVAVHFSREEWQCLDPGQRALYREVMLENHSSVAGLAGFLVFKPELISRLEQGEEPWVLDLQGAEGTEAPRTSKTDSTIRTENEQACEDMDILKSESYGTVVRISPQDFPQNPGFGDVSDSEVWLDSHLGSPGLKVTGFTFQNNCLNEETVVPKTFTKDAPQGCKELGSSGLDCQPLESQGESAEGMSQRCEECGKGIRATSDIALHWEINTQKISRCQECQKKLSDCLQGKHTNNCHGEKPYECAECGKVFRLCSQLNQHQRIHTGEKPFKCTECGKAFRLSSKLIQHQRIHTGEKPYRCEECGKAFGQSSSLIHHQRIHTGERPYGCRECGKAFSQQSQLVRHQRTHTGERPYPCKECGKAFSQSSTLAQHQRMHTGEKAQILKASDSPSLVAHQRIHAVEKPFKCDECGKAFRWISRLSQHQLIHTGEKPYKCNKCTKAFGCSSRLIRHQRTHTGEKPFKCDECGKGFVQGSHLIQHQRIHTGEKPYVCNDCGKAFSQSSSLIYHQRIHKGEKPYECLQCGKAFSMSTQLTIHQRVHTGERPYKCNECGKAFSQNSTLFQHQIIHAGVKPYECSECGKAFSRSSYLIEHQRIHTRAQWFYEYGNALEGSTFVSRKKVNTIKKLHQCEDCEKIFRWRSHLIIHQRIHTGEKPYKCNDCGKAFNRSSRLTQHQKIHMG",
    "output": "May be involved in transcriptional regulation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM",
    "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MWKEFKEFAFKGNIIDLAVAVVIGGAFGAIVTSFVENIITPLMGVIVGGVDFTTLKVTVGEAEILYGNFIQSFVDFIIIAFSIFLAIKFLVKFKRQKEEEEVEAVVEELSKQEELLTEIRDLLKEQSNKN",
    "output": "Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MVKALLVGSKVLIPNVDESRYIYSNGFYGKAIGISKPKDPKDIIRPLELSLIESVYLAKKGLIKVIDKNGEVLEYEKLYEYSSKIINKFDIMYRVYEDLREKGFIVRSGVKYGADFAVYTLGPGLEHAPYVVIAVDIDEEITPHELLSFGRVSHSTRKRLVLALVDRKSESVRYIMFKWVKM",
    "output": "Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MLQYPHINPVALQLGPIKIHWYGLMYLLGIFAGWYLTRYRAKVKPWAPIKPEQVGDLTFYVALGVILGGRIGYIIFYNLPYYFHNPSQMFFLWDGGMSFHGGFIGVLIAFALFARKIGANFFDLGEFVAPVIPIGLGAGRIGNFINGELLGKVTDSPLGMVFPTGGPLPRYPSQLFEFFFEGVVLFSVLWLVTIKKRPRYLVLGLFMFLYGYARFICEFFRQPDPQYGYIFFNWMTMGQILSIPMILLGAVILIAVFIKTRKNKCENI",
    "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MNKVVLLCRPGFEKECAAEITDKAGKREIFGFARVKENAGYVIYECYQPEDGEKLISELPFSSLIFARQWFVVGELLQHLPPEDRITPVVGMLQGVVEKGGELRVEVADTNESKELMKFCRKFTVPLRAALRDAGVLTNYETPKRPVVHVFFIAPGCCYTGYSFAHNNSPFYMGIPRLKFPSDAPSRSTLKLEEALHVFIPEDEWDERLANGMYAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRYRPNRNNISWMVCDMVEKPAKVTALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEHGVNAQIQARQLYHDREEVTVHVRRLWAAVGGRRDER",
    "output": "Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MRNFPVPYSNELIYSTIARAGVYQGIVSPKQLLDEVYGNRKVVATLGLPSHLGVIARHLHQTGRYAVQQLIYEHTLFPLYAPFVGKERRDEAIRLMEYQAQGAVHLMLGVAASRVKSDNRFRYCPDCVALQLNRYGEAFWQRDWYLPALPYCPKHGALVFFDRAVDDHRHQFWALGHTELLSDYPKDSLSQLTALAAYIAPLLDAPRAQELSPSLEQWTLFYQRLAQDLGLTKSKHIRHDLVAERVRQTFSDEALEKLDLKLAENKDTCWLKSIFRKHRKAFSYLQHSIVWQALLPKLTVIEALQQASALTEHSITTRPVSQSVQPNSEDLSVKHKDWQQLVHKYQGIKAARQSLEGGVLYAWLYRHDRDWLVHWNQQHQQERLAPAPRVDWNQRDRIAVRQLLRIIKRLDSSLDHPRATSSWLLKQTPNGTSLAKNLQKLPLVALCLKRYSESVEDYQIRRISQAFIKLKQEDVELRRWRLLRSATLSKERITEEAQRFLEMVYGEE",
    "output": "Required for Tn7 transposition. It may at least play a role in DNA sequence recognition. It seems to be required for specific binding to a region of att-Tn7.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MATSKGRNADPAAALRDCRAAFIGVGVASALVNLLYLTGSFFMLEVYDRILPSRSIPSLIALSLLALLLYAFQGAFELIRGRMLVRIAGALDESLNGRIYRAIVKAPLKLRMQGDGLQALRDFDQVRSFLSGVGPAALFDLPWLPFYIAICFLFHPVIGLIAIIGGLILTLLTYLTNRGTQAPAKKASEAGGLRNVFAQASQRNAEVVHAMGMSARLTALWERRNTEFRDENRRTSDIGNGYGALSKVFRMALQSGVLAAGAVLVIRGEASPGIIIAGSILTARALAPVELAIGNWRGLVAARQSWQRLKELLNALPEADAPLQLPDPHERLTVEGLASGPPAAQRLVVSDVNFTVRAGGAVGVIGPSASGKSSLARAILGIWPAYRGSVRLDGAALDQWDSDALGKHVGYLPQDVELFAGTIAQNICRFAEDATSEAIVAAAKAARVNDLILRLPNGYDTEIGDGGMTLSAGQRQRVALARALYGDPFLVVLDEPNSNLDAEGEQALSEAIMSVRSRGGIVIVVAHRPSALASVDLVLMMNEGRMQAFGPKEQVLGQVLRPQQVERQNALKVVAEGQEAKQ",
    "output": "Mediates secretion of glycanase ExsH."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MGQPAPYAEGPIQGGDAGELCKCDFLVSISIPQTRSDIPAGARRSSMGPRSLDTCWGRGPERHVHRLECNGVIFTHRNLCLPGGKTKTENEEKTAQLNISKESESHRLIVEGLLMDVPQHPDFKDRLEKSQLHDTGNKTKIGDCTDLTVQDHESSTTEREEIARKLEESSVSTHLITKQGFAKEQVFYKCGECGSYYNPHSDFHLHQRVHTNEKPYTCKECGKTFRYNSKLSRHQKIHTGEKPYSCEECGQAFSQNSHLLQHQKLHGGQRPYECTDCGKTFSYNSKLIRHQRIHTGEKPFKCKECGKAFSCSYDCIIHERIHNGEKPYECKECGKSLSSNSVLIQHQRIHTGEKPYECKECGKAFHRSSVFLQHQRFHTGEQLYKCNECWKTFSCSSRFIVHQRIHNGEKPYECQECGKTFSQKITLVQHQRVHTGEKPYECKECGKAFRWNASFIQHQKWHTRKKLINGTGLSAVKPYCPCAILSPLPPQHTCSALAPPGPPLSSSHAVVLPPSVPFFLLLPSSEKANPSPVQIAHFFQDLAFPGKSSLQSPNPLSHSL",
    "output": "May be involved in transcriptional regulation."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAKDIKFSEDARRSLLNGVNKLANTVKTTLGPKGRNVVLEQSYGAPTITNDGVTIAKAIELEDHYENIGAKLVAEAASKTNDIAGDGTTTATVLTQAIVQEGMKNVVAGANPVGIRRGIEKATKAAVDQLHKNSHKVSSRDQIAQVASISSASKEIGDLIAEAMEKVGKDGVITIEDSRGIETELSVVEGMQFDRGYLSQYMVTDNDKMEADLENPYILITDKKISNIQDILPMLQEIVQQGRSLLIIADDVTGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKEQLADIAALTGGTVISEDLGLELKDTQLSQLGQARRVTITKDSTTIVDGSGAKEAIQERVDTIRKQIEDTSSDFDKKKLQERLAKLTGGVAVIHVGAATETELKERRYRVEDALNATRAAVDEGYVAGGGTALVNVEEAVKATKGDTDDEQTGINIVARALTAPVRQIAENAGQEGSVVVDHLRKVDPEVGYNAAEDKYVNMIDEGIIDPTQVTRSALQNAASIAGLLLTTEAVVAEIPEDKPEAAPAQPGMM",
    "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAFLEDANHTAVTEFILLGLTDDPVLKVVLFSIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDVGYSSTVTPKMLANFLVERSTISYLGCTIQLFSGAFFGTLECFLLATMAYDRFIAICNPLLYSTKMSTQVCIQLLVGSYIGGFLNASSFLLSFFPLLFCGPNRVNHFFCDLAPLIELSCSGSNVPIVPASFCSAFVIIVTVFVIAISYTYILITILKMRSTEGRQKAFSTCTSHLTAVTLFYGTITFIYVMPKSSFSTDQNKVVSVFYMVVIPMLNPLIYSLRNNEIKGALKRQLARKIFS",
    "output": "Potential odorant receptor."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "ADANKVWPTGLTVAEAEELHTYVTNGFRVFVGIAVVAHVLVFAAHPWGRGGALVA",
    "output": "Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MIRSARLISNIKFGQKNIRQFSTNTNWWANVQKGPEDPILGVSIAYNKDTSPSKINLGVGAYRDENGKPYVLDCVKKADKKIYEANVDHEYAPIVGVAAFNQLAAQLALGEECKHIKEKRIATVQSISGTGALRIAADFFARFLKGKTAYVPNPTWGNHNVIFNDAGIPVKSYGYYNPATCGLNFEAMTKDIAAAPEGSIILLHACAHNPTGVDPTAEQWKKISEICKERGHFVLFDFAYQGFASGSPEKDAAAVRMFVEDGHNIALCQSFAKNFGLYGERIGAFSILTETSDQALNVESQLKILIRPMYSNPPVYGARLVQAILKDKELTNEWRSEVKGMADRIINMREQLVKYLKKHGSTRDWSHITTQIGMFCFTGLTPEQVDRLANEYHIYLTRNGRISIAGINSTNVEYLAKAMAAVTKDN",
    "output": "Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSESQPPRRGRFPLPLSATTPVVRRFVSTGQAVLQPVPPRPQRPASEITRETARPAILAGHGLDSDGFRARMIERLRADGCRDEHVLRAMSRVPRHLFVDSALAAQAYEDTSLPIGHGQTISKPSVVARMLGLLRQRPGGAQLGRVLEIGTGCGYQAAVLCRLASQVYSIERLKALHDRARENLAPMRRDQLRLIYGDGLHGHGPNAPFDAIIAAAGGHAIPQAWLDQLAVCGRLVAPMHDAQRGTQVLVVVDRMPDGSLVQHRHETVRFVPLESGTSDYKPA",
    "output": "Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTREREPGKSRTKSGSGTTDQVFCSFCGRSAQEVNSMIAGPKAFICDRCIKTSFDILRKEVNAVPPVAKVPEQPFQPRLVSPKAIMDSLGQYVVGQDAAKKSLAVAVYNHYKRIDSQEQQQADDEVVIEKSNILLIGPTGTGKTLLAQTLANLLEVPFSIVDATSLTEAGYVGDDVETILARLLHAADFNLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQALLKILEGAVVGVPPKGGRKHPEQQLININTKNILFICGGAFEGLDKLIAKRVSKSSMGFGAKVKTTQIGYDPEILKLVMQDDLHEYGLIPEFIGRLPVISTLEMLDEKALRNILVEPKNAITKQYKKLFEMDGVELEFTEEALDKVVKIAIERGTGARALRSVLENVMIDIMFEIPSMKNTHKCVITADTIENKAAPEYFSGDRKKKKIA",
    "output": "ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPRTTPAPGHPARGARTALRTTRRRAATLVVGATVVLPAQAATTLKEAADGAGRDFGFALDPNRLSEAQYKAIADSEFNLVVAENAMKWDATEPSQNSFSFGAGDRVASYAADTGKELYGHTLVWHSQLPDWAKNLNGSAFESAMVNHVTKVADHFEGKVASWDVVNEAFADGDGPPQDSAFQQKLGNGYIETAFRAARAADPTAKLCINDYNVEGINAKSNSLYDLVKDFKARGVPLDCVGFQSHLIVGQVPGDFRQNLQRFADLGVDVRITELDIRMRTPSDATKLATQAADYKKVVQACMQVTRCQGVTVWGITDKYSWVPDVFPGEGAALVWDASYAKKPAYAAVMEAFGASPTPTPTTPTPTPTTPTPTPTSGPAGCQVLWGVNQWNTGFTANVTVKNTSSAPVDGWTLTFSFPSGQQVTQAWSSTVTQSGSAVTVRNAPWNGSIPAGGTAQFGFNGSHTGTNAAPTAFSLNGTPCTVG",
    "output": "Hydrolyzes both cellulose and xylan. Has also weak endoglucanase activity.; "
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MPTQAKVATVAELTDRLNRAQMLLVADYRGLTVAELNELRKKVREKGGEVIIAKNTLTRLAAREAGKTEIEEFLGGPTALAFSYDDIPGVAKAIDDFFKASKKDIKVKGGIVGTSKITGADVERVAKMPTRDESLAKILGGINAPASRIVGGLKGVMRNIAYILGAHAQKGAEG",
    "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MPLPIVAIIGRPNVGKSTIVNRLAESKDAIVHDEPGITRDRTYRNAYWEDREFQVVDTGGLVFDDNTEFLPLIREQAMAALVEASVAIFVVDGQTGLTGGDEEIAQWLRQQTIPILLAVNKCESITEGLTQAAMFWELGLGEPYPISGIHGNGTGELLDDLITYLPTQGEITETNQTKIAIVGRPNVGKSSLLNSFIGEKRAIVSPISGTTRDAIDTVVERNGKTYRLIDTAGIRKKKNVEYGAEFFGINRAFKAIRRAEVVMFVIDALDGVTEQDQKLANRIIEDGRACVIVVNKWDAIEKDNYTIYTYEQEVRSRLYFVEWAEMIFVSALTGKRVEKIINLIDNAANEYQRRVTTSVINEVLEEAISWNSPPTNRQGRQGKIYYGTQVTSKPPTIALFVNDPKRFPENYRRYIQSQFRQHLGFTGTPIRLLWRGKKAREVEQNTVNRATRV",
    "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MTGQLVQYGRHRQRRSYARISEVLELPNLIEIQTSSYQWFLDEGLREMFQDISPIEDFTGNLSLEFIDYSLGEPKYPVEESKERDVTYSAPLRVKVRLINKETGEVKDQDVFMGDFPIMTDTGTFIINGAERVIVSQLVRSPSVYFSGKVDKNGKKGFTATVIPNRGAWLEYETDAKDVVYVRIDRTRKLPVTVLLRALGFGSDQEIIDLIGENEYLRNTLDKDNTENTDKALLEIYERLRPGEPPTVENAKSLLDSRFFDPKRYDLASVGRYKINKKLHIKNRLFNQRLAETLVDPETGEILAEKGAILDRRTLDKVLPYLENGIGFKKLYPNGGVVEDEVTLQSIKIYAPTDQEGEQTINVIGNAYIEEGVKNITPSDIIASISYFFNLLHGVGDTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTNTITPQQLINIRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSFAKVNRFGFIETPYRRVDPETGKVTPRIDYLTADEEDNYVVAQANARLNDDGSFVDDSIVARFRGENTVVPKDRVDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMQPESPIVGTGMEYVSAKDSGAAVICRHPGIVERVEAKNIWVRRYEEVDGQKVKGNLDKYSLLKFVRSNQGTCYNQRPIVSVGDEVEKGEILADGPSMEKGELALGRNVMVGFMTWDGYNYEDAIIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVGEDALRNLDERGIIRVGAEVKDGDLLVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGGGGIILDVKVFNREDGDELPPGVNQLVRVYIVQKRKISEGDKMAGRHGNKGVISKILPEEDMPYLPDGTPIDIMLNPLGVPSRMNIGQVLELHLGMAARRLGLHVASPVFDGAREEDVWETLEEAGMSRDAKTVLYDGRTGEPFDNRVSVGIMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGRVKTYEAIVKGDNVPEPGVPESFKVLIKELQSLGMDVKILSSDEEEIEMRDLEDDEDAKQNEGLSLPNDEESEELVSADAERDVVTKE",
    "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MAGQKIRIRLKAYDHEAIDASAKKIVETVTRTGARVVGPVPLPTEKNVYCVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ",
    "output": "Involved in the binding of tRNA to the ribosomes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MARYTGPVTRKSRRLGTDLVGGDQSFEKRPYPPGQHGRARIKDSEYRQQLQEKQKARFTYGVMEKQFRRYYEEAVRHSGKTGEELLKILESRLDNVVYRAGLARTRRMARQLVSHGHFSVNGVHVNVPSYRVSQYDIIDVRDNSLNTVPFQIARETAGDRPIPSWLQVVGGRQRILIHQLPERAQIEVPLTEQLIVEYYSK",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MKHWIQENYKNRSWAGELNESQEGKQIVLFGWSFRFRDQGGVIFIDLRDRTGIIQVVARKELLGDSFTLAEKVRSEYVLAVRGTLKKRDLESINPRMQTGTIEVVLDQLEILNVAKTPPFSLDEFDEVSEELKLKYRYLDFRREELKNRMIKRHEFIFAIRNYLNKRKFVEIETPILNKSTPEGARDFLVPSRLNPNQFYALPQSPQIFKQILMVGGMERYFQIVKCFRDEDLRADRQPEFTQLDMEFSFVSQEEILSEIEGLVETIYKEVFNIQLSIPFPRMTYNTAMEEYGSDKPDLRFGMKLVDVSEIVKDCDFNVFAGAVKNGGTVKVVCVPGGSIISRKEIEDYTAWLNRDYKAKGLAYMKHGTEGLESTITKRFKKEELEAISKACGSKEGDMLFFGADEREIVNHSLGALRLKLSERFETPKENEINITWIVDFPMFEWNKDHKRWDALHHPFTSPSDESIPFFESMETLQKNAGNATAKAYDLVMNGVEIGGGSIRIHSREIQNKVFQILGINEEEAKEKFGFLLEALEFGAPPHGGLAFGIDRMLMLLTGGKSIRDVIAFPKTQKGLCLMSECPSPVEEKQLQELKIKLAKV",
    "output": "Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MAKLMNKLVDSFEHDEIPDVGCVRAVLAELVLTFLFVFTGVSAAMAAGSDGKPGDAMPMATLAAVAIAHALAAGVLVTAGFHVSGGHLNPAVTVGLMVRGHITKLRAVLYVAAQLLASSAACVLLRFLSGGMVTPVHALGRGISPMQGLVMEVILTFSLLFVTYAMILDPRSQVRAIGPLLTGLIVGANSLAGGNFTGASMNPARSFGPALATGDWTNHWVYWIGPLLGGPLAGFVYESLFLVQKMHEPLLNGEV",
    "output": "Aquaporins facilitate the transport of water and small neutral solutes across cell membranes."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MANSVYVKFEVPKEIADKVYEALEIARDTGKIGKGTNEVTKNIERNNVALAVIAEDIEPAEIVAHLPILAEEKEIPYVYLPTKEELGEAAGLNVGTASACIIDAGEGQELVDEIVEKVAELKN",
    "output": "Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MEAVQAAAAATSSGGSSGSVPGSGSGSASKLIKTEPIDFEMLHLEENERQQDIEREPSSSNSNSNSNSLTPQRYTHVQVQTVPPRQPTGLTTPGGTQKVILTPRVEYVQQRATSSTGGGMKHVYSQQQGTAASRSAPPETTALLTTTSGTPQIIITRTLPSNQHLSRRHSASPSALHHYQQQQPQRQQSPPPLHHQQQQQQQHVRVIRDGRLYDEATVVVAARRHSVSPPPLHHHSRSAPVSPVIARRGGAAAYMDQQYQQRQTPPLAPPPPPPPPPPPPPPPQQQQQQYISTGVPPPTAAARKFVVSTSTRHVNVIASNHFQQQQQQHQAQQHQQQHQQHQQHQQHVIASVSSSSSSSAIGSGGSSSSHIFRTPVVSSSSSSNMHHQQQQQQQQSSLGNSVMRPPPPPPPPKVKHASSSSSGNSSSSNTNNSSSSSNGEEPSSSIPDLEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQRALATELDDQPRLLAAVLRAHLETCEFTKEKVSAMRQRARDCPSYSMPTLLACPLNPAPELQSEQEFSQRFAHVIRGVIDFAGMIPGFQLLTQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARFLVDSTFNFAERMNSMNLTDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLETMPDLRTLSTLHTEKLVVFRTEHKELLRQQMWSMEDGNNSDGQQNKSPSGSWADAMDVEAAKSPLGSVSSTESADLDYGSPSSSQPQGVSLPSPPQQQPSALASSAPLLAATLSGGCPLRNRANSGSSGDSGAAEMDIVGSHAHLTQNGLTITPIVRHQQQQQQQQQIGILNNAHSRNLNGGHAMCQQQQQHPQLHHHLTAGAARYRKLDSPTDSGIESGNEKNECKAVSSGGSSSCSSPRSSVDDALDCSDAAANHNQVVQHPQLSVVSVSPVRSPQPSTSSHLKRQIVEDMPVLKRVLQAPPLYDTNSLMDEAYKPHKKFRALRHREFETAEADASSSTSGSNSLSAGSPRQSPVPNSVATPPPSAASAAAGNPAQSQLHMHLTRSSPKASMASSHSVLAKSLMAEPRMTPEQMKRSDIIQNYLKRENSTAASSTTNGVGNRSPSSSSTPPPSAVQNQQRWGSSSVITTTCQQRQQSVSPHSNGSSSSSSSSSSSSSSSSSTSSNCSSSSASSCQYFQSPHSTSNGTSAPASSSSGSNSATPLLELQVDIADSAQPLNLSKKSPTPPPSKLHALVAAANAVQRYPTLSADVTVTASNGGPPSAAASPAPSSSPPASVGSPNPGLSAAVHKVMLEA",
    "output": "Implicated in the regulation of ecdysone-triggered gene hierarchies. Probably plays a key role in mediating the regulation of the larval molt by 20-OH-ecdysone."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "SVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEEDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYIKTFQGPPHAIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAXYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLXKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDAVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAAEGNDIIREASKWSPELAAACEVWKEIRFNFQAVDTLDPLKS",
    "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MDSNSWINCPPVFSSSPSSRRYQSRSDLYLGDVEGEDDLKAEFMCPFCADEFDIVGLCCHIDVNHPVEAKNGVCPVCTKKVGLDIVGHITTQHGNVFKVQRRRRLRKGGYSSTYLTLKKELREANLQSLGGSSTFIPSSNIDSDPLLSSFMFKPPSAIPITEGDSVAQVSPKDTSKSKIQQESFSNEDQEKAKKSKFVRGLLWSTMLEDKF",
    "output": "Involved in both red and blue light signaling."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MTQQSNSADRKPRGKGPKRPRKPKVDPFSIGELEITDYKDVKMLRRFVSDTGKILPRRRTGLSAKHQRRIAQTIKVARQLALLPYTEKLVRK",
    "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MQVNPNPNKVPVELNRTSLYLGLLLVFVMGILFSSYFFN",
    "output": "One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSQQVGNSIRRKLVIVGDGACGKTCLLIVFSKGQFPEVYVPTVFENYVADVEVDGRRVELALWDTAGQEDYDRLRPLSYPDSNVVLICFSIDLPDSLENVQEKWIAEVLHFCQGVPIILVGCKVDLRNDPQTIEQLRQEGQQPVTSQEGQSVADQIGATGYYECSAKTGYGVREVFEAATRASLMGKSKTNGKAKKNTTEKKKKKCVLL",
    "output": "Acts as a central regulator in the cell wall integrity signaling pathway, which is regulated by the cell cycle and in response to various types of cell wall stress. Integrates signals from different cell surface sensors, and activates a set of effectors, regulating processes including beta-glucan synthesis at the site of wall remodeling, gene expression related to cell wall biogenesis, organization of the actin cytoskeleton, and protein- and secretory vesicle-targeting to the growth site. Activates the protein kinase C (PKC1) MAP kinase cascade, the beta-1,3-glucan synthase (FKS1), the formin BNI1, the exocyst component SEC3 and the transcription factor SKN7."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MSLNDNTNLSSHTPMMQQYLRLKAEHPEILLFYRMGDFYELFYDDAKRASQLLEISLTKRGSSAGEPIPMAGVPYHAVENYLAKLVHLGESVAICEQIGDPALSKGPVERKVVRIVTPGTISDEALLNERQDNLLAAIWQSTRGFGYATLDISSGRFRLAEPTDRETMAAELQRTNPAELLYPEDFAAMDLIENRRGLRRRALWEYELDTARQQLNLQFATRDLSGFGVEQAHHALRAAGCLLQYVKDTQRTSLPHIRSLTIERQQDGIIMDAATRRNLEITQNLAGGSDNTLASVLDKTVTPMGSRMLKRWLHMPLRNAQTIALRQQSIRTLQDLNDSLPPLLRQVGDLERILARLALRTARPRDLARMRHAFQQLPQLNNELADSDNAHLQTLRSQMGEFTELRELLEHAIVETPPVLVRDGGVIAPGYNQELDEWRALADGATDYLDRLEIREREKLGLDTLKVGFNGVHGYYIQVSRGQSHLVPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALSLEKALYEQLFDRLLPHLAALQDSAAALAELDVLTNLAERAWTLNYSCPTLSDKPGIKLTGGRHPVVEQVLKDPFIANPLSLSPQRRMLVVTGPNMGGKSTYMRQAALITLMAHIGSFVPAEQAIIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAESLANRIKAMTLFATHYFELTTLPEQIEGVANVHLDAVEHGDTIAFMHSVQEGAASKSYGLAVAALAGVPKDVIKRARQKLKELEALSGSAASTRADGSQLPLLVEETSPAVEALEALDPDSLSPRQALEWIYRLKSLV",
    "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MDVFKQSEVWFVIGSQNLYGPKTLQQVMDNAHQVVNSLNSEAGLPVKLVLKPLVTTPDEITALCREANYDTACIGIMTWLHTFSPAKMWIGGLSILNKPLLQFHTQFNAQIPWETMDMDFMNLNQTAHGGREFGFIGARMRQQHSVITGHWQDKEAHQRIGQWMRVAAAKQESQQLKVARFGDNMREVAVTEGDKVAAQIQFGYSVNAYGIGDLVAVVDAVSKGDIDTLVEEYEATYRFTDAVKLNGDKRENLLDAARIELGMTRFLEQGGFKAFTTNFENLYGLKQLPGLAVQRLMQQGYGFGGEGDWKTAALLRILKVMGTGLKGGTSFMEDYTYNFQPGNDLVVGSHMLEVCPSIAKEEKPLLDVQHLGIGGKADPARLIFSTPAGPALNASLIDMGNRFRLLVNVVDTVEQPHPLPKLPVARAIWQAQPSLATAAEAWIIAGGAHHTVFSQAVGVDELRLYAEMHGIEFLLIDNDTTLPAFKNEIRWNEVYYQLNR",
    "output": "Catalyzes the conversion of L-arabinose to L-ribulose."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MSKRDYYEVLGAAKDASAQDLKKAYRRLAMKYHPDRNPDDKEALAKFKEAKEAYEVLADEQKRAAYDQFGHAGVNGQGGGPGAGAGAGGFGDIFGDIFGDIFGGAGGGGGRRGPSRGADLRYTLELSLEQAVRGCDEKIRIPTWDSCDVCHGSGAKEGSQPVTCTTCGGVGQVRMQQGFFTVQQACPTCKGEGKIIKDPCGNCGGQGRVQNTKTLSVKIPAGVDTGDRIRLAGEGEAGVHGAPSGDLYVQVAVREHDIFQRDGDNLYCEVPISFVDATLGGELDVPTLNGKVKLKVPAETQSGKLFRLRGKGVAPVRGGAPGDLLCKVVIETPVKLSSEQKELLRKFQESLESGGNRHNPRKNNWFEGVKRFFDTK",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MARKSLIQRERKRQKLEQKFHSIRRSSKKEISKVSSLSGKWEIHGKLQSPPRNSAPIRLHRRCFLTGRPRGNYRDFGLSGHILRERFHACLLPGATRSSW",
    "output": "Binds 16S rRNA, required for the assembly of 30S particles."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTNVLLVALGGSIGAVLRYLLSIFMIQVFGSSFPFGTLLVNLLGSFLMGAVYALGQLSHISPEIKALIGIGLLGALTTFSTFSNETLLLLQEGLWHKAILNVLLNVTLCLFMVYLGQQLIFSRV",
    "output": "Important for reducing fluoride concentration in the cell, thus reducing its toxicity."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MASYFQLSSMPKRLLQYALSSLEVFETDALDLENLDIAWGKNSTFEFKDVGLRLKKLETLLQLPSTIALSKAKVLLLRLTIPVDIYSSPILVEVDGVDVQLRVREEKGVYNPRTNHDRFRKKSTSKNQGLDPTLPTAEDLAASFLQTESREEKEELEAAILGETQDVSESVTSNEGGDSPVGTGTALSLPAFMARFLQGIVDRLQVRVHGITFNVDLDIPAEGPTSNRTTDPVTVQLKIDDVDIEGVTHDIESTQTRGGKDITSLFKEGKRLVCLSNIQGALITEANLFQTLSRSSSVVSPVPPHSDITEPRRAAEKERSSEETQVMSVESAGGFDRVASPSPPSSPASSLRVSESSLPEIKRPSPPLRPVKTSPSVKASTVANDSGQFDDASEDGHSSPSGSGIGDVDTSEMGDSLLQSSAILDQVTDSLLLDHPEGNDMRSSQSQSEHSTPGENSRTSTPRASAHISSPSSQTPEFNAFHSVNRAHNMLQSTMLPPRAHTRFSVERISHSQPTLPPTTAPLDRTYLVQQSRVPSEDSMSESSSSTFNEEIGDDLAQSQLFSHEEAESMYMSAVSFTSAAPIPGGWADSGTESEDARSPPLTPTDYNFRGEKLDNLENARHYIPSDGASDIDSLEKSTILPLRPLHASSRSIGSMRSETPRQSRLLHKVSSDVSVKSTVTSDDYNRMTKQIFSLDQVAIYIPAMNDPSSDPVDAAAESALFGSTFDGHSDSHSNTMDLPGAFSTHLPREQRSRSSPKPTPRVPTQPPQKPEENKSIEVDVGNLLAQFDISIGRLIYKLVCQIQESMKKKTQAATVSSKPTSSSPEPHLRVSAQTVSLKFLEHLKGTLGSRIAEPQTKALDSDVLLKTTIKGLNVSRNPSDTTTKTSVTLQKFIFGYAQENIVSFDAGLQMRASTRDLAASAGIDVSANIYQSHDGTRFEVHTLPLHVAVDLQHLDETFSWFGGLSSVLNLGSSMASNTTVISSPVIKPKSKGVKFNTPIEPDDQTMAVQNKADVRIGGLILDLVGTECSVGVETSAVKLISREEGIGIGIDKIRLSGPHLRHSVDDPAIVIDVSTTRIEFLNAPKDNDIDRLLALIAPSNSKYDQDDDILLDTLLRQRQQGSVLRLTVDDLQAKIGRLNELSYLPELGEEVARLSTVTKYLPDDDRPGLLSLVKIKKLGIDVDVNNSVGSLQLKATDLDMAQIPIPSLVALSVGTVSAYRNYSEELIGAGTDQVFNRPELRIPSIMARLIGDEMEPIVKIKLWNLRVEYRVPTLMVLLGLADTATGNEMSASITASVATLRDLAQPQTPKGKEKGVEKRPASSSSPAKPMTIDVVLKDCIVGLNPLGLPSKILAVLTEAHVAAVLPKDQNASVTAELSKASLLVIDNVAHLASTVQSDHNRNSFNGGSNQVADLTSTGYVSVSYISSAKATVLLSVDDDGQNCLDVELRDDLFVLESCADSTQTLISVLGKLAPPGKPPKKEENTYQTKVVPLNNLLASVSIDAFGTPEGQYEFSNDFTELGDLTEEGESELGFDSDYCKGSSDDGYKQAVLDDVEDSLASLNLTARDTRDGVLLDSFAEEPEIDNVALSFHEDHFGTGSSLEHSAHRWNSARNTYDTSNYSKVKKSPLRVRVRDVHIIWNLFDGYDWQDTRDTISKAVQDIESKAIEKRARNERRSTWEQDIDDDEDTERGTFLLNSMWIDIPNSRDPRELAAAINQQLNDNATETESIATTSYTVTPSRQGGGRAAKELRLNRTKHHKIAFELKGVCVDLVTFPPLSGETQSSIDIRVNDLEVFDNIRTSTWRKFATYMQDAGEREKGSNMVHIEIINVKPVPTLAATEMVIKVTILPLRLHVDQDALDFITRFFEFKVESDIEPEAPGEKPFLQRVEVNSIDVKLDFKPKRVDYSGLRSGRTTEFMNFMILDGADMTLRHCIIHGCSGFDKMGQVLNDIWTPDVKENQLPGILAGLAPVRSIVNVGSGFKDLVVIPMNEYKKDGRIVRNISRGAAIFAKTTGTELVKLGAKVAIGVQTVLQGAEGLLGPQDSSLPHANSSDDEDERKQISLYANQPVGVMQGLRGGYASLQRDLIMARDAIIAVPGEVMEDGNAKGVLKAVRKHAPTVILRPVIGVAKGAGQVLMGATNTLDKKNLERVDAKYKKH",
    "output": "Lipid transfer protein required for autophagosome completion and peroxisome degradation. Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion. Atg2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region. The latter binding is assisted by an atg18-PtdIns3P interaction. Atg2 then extracts phospholipids from the membrane source using its NR and transfers them to atg9 to the IM through its predicted beta-sheet-rich structure for membrane expansion."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTAGPTSLDLDVSVQRTLDNNLATEAYERRIKRLEQEKLELTRKLQESTQTVQALQYSTVDGPLTASKDLEIKSLKEEIEKLRKQVAEVNHLEQQLEEANSVRRELDDAFRQIKASEKQIKTLQQEREELNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKAESLRQELRRAERAKKELEVHTEALIAEASKDKKLREQSEHYSKQLENELEGLKQKQISYSPGICSIEHQQEITKLKTDLEKKSIFYEEEISKREGIHASEIKNLKKELHDSEGQQLALNKEILVLKDKLEKTRRESQSEREEFENEFKQQYEREKVLLTEENKKLTSELDKLTSLYESLSLRNQHLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQALASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNILTECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTPTDALDQFEIADCAPLPAHTPTLRKKGCPASTGFPPKRKTHQFFVKSFTAPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTVCPVPPEQTKGPLGIDPQKGVGTAYEGHVRIPKPAGVKKGWQRALAVVCDFKLFLYDIAEGKASQPTSVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSAPSNKCSILMLADSENERSKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIVRVGDNKKIHQIELIPSDQLVAVISGRNRHVRLFPMSALDGRETDFYKLAETKGCQTIAAGKVRHGALSCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPCNVQWMAIFSEHLCVGFQSGFLRYPLNGEGGPCNMLHSNDHTLSFISHQPMDALCAVEISNKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNTEGSLNLLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYNTKRQPMPSPSEGSLSSGGMDQGSDAPARDYDGEDSDSPRHSTASNSSNLSSPPSPISPQKTKSLSLESTDRGSWDP",
    "output": "Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LRP35A, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates: PPP1R12A and LIMK2. May play a role in TFRC-mediated iron uptake (By similarity). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation . Triggers the formation of an extrusion apical actin ring required for epithelial extrusion of apoptotic cells (By similarity)."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MVLKVFKDHFGRGYEVYEKSYREKDSLSFFLTKEEEGKILVVAGEKAPEGLSFFKKQRAEGVSFFFCERNHENLEVLRKYFPDLKPVRAGLRASFGTGDRLGITTPAHVRALKDSGLFPIFAQQSVRENERTGRTWRDVLDDATWGVFQEGYSEGFGADADHVKRPEDLVSAAREGFTMFTIDPSDHVRNLSKLTEKERNEKFEEILRKERIDRIYLGKKYSVLGEKIEFDEKNLRDAALVYYDAIAHVDMMYQILKDETPDFDFEVSVDETETPTSPLFHIFVVEELRRRGVEFTNLALRFIGEWEKGIDYKGDLAQFEREIKMHAEIARMFEGYKISLHSGSDKFSVYPAFASATGGLFHVKTAGTSYLEAVKVISMVNPELFREIYRCTLDHFEEDRKSYHISADLSKVPEVEKVKDEDLPGLFEDINVRQLIHVTYGSVLKDASLKERLFKTLEQNEELFYETVAKHIKRHVDLLEG",
    "output": "Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA)."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MANSAQARKRARQATKARAHNASLRSRLRTAIKAVRKAIVGGDKAAAQAVFRTSMSTIDSVADKKIIHKNKAARHKSRLSAAVKAMAA",
    "output": "Binds directly to 16S ribosomal RNA."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MNTVRVTFLLVFVLAVSLGQADKDENRMEMQEKTEQGKSYLDFAENLLLQKLEELVAKLLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK",
    "output": "Probable ion channel inhibitor."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MIDDNIENNEQTINDIAEEIVETANPEVTALKAEIEELKDKLIRTTAEIDNTRKRLEKARDEAKDYAIATFAKELLNVSDNLSRALAHKPANSDVEVTNIIAGVQMTKDELDKVFHKHHIEEIKPEIGSMFDYNLHNAIAQIEHPDHAPNSIITLMQSGYKIRDRLLRPATVQVVKKP",
    "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAVAIEAPFHVLAVDDSLPDRKLIERLLKTSSFQVTTVDSGSKALEFLGLHDHEDSPISTQSDQQEVGVNLIITDYCMPGMTGYDLLKKIKESSYLRDIPVVIMSSDNIPSRINRCLEEGADEFFLKPVRLSDMSKLKPHILKSRCKEHYQQEQHLQSNSESNNSSNPTSENSSSSTSTNSHKRKAVDEEILPHTIRPRHS",
    "output": "Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAAQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKGLQEITDWIEKRLC",
    "output": "Catalyzes the hydrolysis of esters."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "MLEEKKKQESFEIQRIYIKDVSFEAPNTPNIFHVNWIPTIKLNLNTTTKKIKENIFEVVLMVKVTVKIKEDLVFLCDIDQAGIFFIANINEKRLKHCLYSYCPNILFPYARTCISNLVSCGSFPQMNLAPINFDALYHDHIK",
    "output": "One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA."
  },
  {
    "instruction": "Generate the functional description in free-text form based on the protein sequence.",
    "input": "DPFGSVFSHQEFSPDEEMSRILLTSQTQKIDWKYLNKPWFRKNMQEQNFKLLIDRQRWFRTNSSVSNEFFRSNTLYESYQYLSNLFLSNGTLLAQLTKTLLRKNGFPSEWLCTLSNNERLV",
    "output": "Probable ATPase of unknown function. Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MAKASKGKHQSGPSNHSESIDLVRKALYGNKKVRSLKMNPDMWEKHEVINRAWRIHEYRQEKQRENLLKNQFSAMKIACEELKHTSETLYKAAMSDSINRRFPVETRTPTDTPPRLSK",
    "output": "Involved in mitochondrial genome encoded proteins translation."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MIRVICNNETYELPQGTTAADFASKIKNSHYFAGVVINDQIKDLSTTLNEGDTLRFVTFTDPEGREIFLHTSAHILAQAILRLWPDAIPTIGPVIDQGFYYDFANLSISEDDFLMIENMMGQIAEEKFAVQKKTFNSKHEALEEFARNPFKVELIKELPEGESITAYSQGEFMDLCRGPHLPSTGPVKAFKLLRTSAAYWRGDPQRESLVRIYGVAFPTTKELKEHLHQLKEAKKRDHRVLGMKLDLFSQQECSAGMPFFHPRGMIIWDALIGYWKRLHQLAGYKEIQTPQLMSRSLWEVSGHWSNYRENMYTLKIEDEDYAIKPMNCPGCMLYYKTRLHSYKQFPLRIAEIGHVHRYEVSGALSGLMRVRAFHQDDAHVFLTPEQVEEETLNILHLVSELYSTFGLEYHLELSTRPEKATIGSDELWELATAALERALVNSHTPFIINPGDGAFYGPKIDIHVKDAIQRTWQCGTIQLDMFLPERFELEYTNAQGEKSTPVMLHRALFGSIERFLGILIEHFKGRFPLWLSPEHIRVITVADRHQPRAQKLATAWQKLGFVVTVDDSNESVSKKIRNAQNMQVNYMVTLGDREIEQNTLAIRTRDNRVLNDMTEDKFLNTLLEEKNSLSLTPLL",
    "output": "Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MEKGHSDLPRQPERVAQNPFLTFDQDSFPSSYGSSLNVSEQTSGSSSTSPLPQISCLLRKDDVPLANKELSRSLIHVQELSRYPPFYNQDHQHLGVPRSRVGSDVWKMREKSFLSPSQFSSIDLSWVYRSKEEDDDFHDPKSSVVSLMGEEDYLGWSRFCDLFFLFVLSLGIGLLFIVFPALTFTGNITPSKEKFDAIMANQITDHLFAHMRVPRTNLIDKDTPSTAYHRTGYNGRKYNLVFSDEFNKEGRSFYSGNDQFWEAVNIHYAATNDLDWYDPDAITTVNGTLAIQLDAFWNRDLNFRSGMLQSWNKLCLKGGIIEVSASLAGSGEHAGLWPGIWTLGNLARPGYMATTDGVWPYAYSQCDVGITPNQSSYDGISYLPGQKLPNCVCLNEDHPSPGVGRGAPEIDILEGSTEKLHPDDELDIGVVSQSGQFAPFDFFWLPNYDYLAVYNDSITHMNSYVGGPFQQALSGITTLNNTWYGGNAFQIYGFDYKPGEGTNGYVSWFVGPNYTWSMLGSAVGQNGNVGPRQISEEPMSIIFNLGISNNWAYYYFRDLSFPAVMYIDYIRIYQDPDDTNSHIGCDPPGYPTTKYIEEHPLAYKNPNATTWEMAGYTWPKNSLMHKCNT",
    "output": "Required for synthesis of the major beta-glucans of the yeast cell wall."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD",
    "output": "May play a role in photosystem I and II biogenesis."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MGRDTIADIITSIRNADMNRKGTIQIASTNITENIVKILLREGFIKNVRKHQENNKYFLVLTLRHRRNRKGPYRTILNLKRISRPGLRIYSNYQRIPRILGGMGIVILSTSRGIMTDREARLEGIGGEILCYIW",
    "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."
  },
  {
    "instruction": "What is the functional description of the protein sequence?",
    "input": "MRTPEEIIIRPLVTEKSTGLMADNKYTFLVDPGANKIEIKHAIEKLFNVKVLKVNTLMERGKLRRVGRFQGRQSDRKKAIVTLRPGDKIQVFEGLE",
    "output": "One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MASTFAIGLGVATAAFLGRAGYVALRRYQGGINAMGKAFYKGGFEPRMTRREAALILELPERTLNKEKVRKKHRQLMLLNHPDRGGSPYLATKINEAKEFLDKHI",
    "output": "Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1/sscA) (By similarity)."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MQNYFQLLGLPQEYNINLKILEKQYFAMQVKYHPDKAKTLQEKEQNLITAAELNNAYSTLKDALKRAEYMLLLQNINLNDEKTRSLLSPLELSIFWDEMEIIENTILFSDLEKIKDKYELMKKLEIDSLKQAFEEQNLSDATIKTSKLKYIGTLLHKLQEKIKSCK",
    "output": "Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA."
  },
  {
    "instruction": "Predict the general functional description of the protein sequence.",
    "input": "MAPGATATPFLPTVSNETTLRESFVRDEDERPKVAYNVFSSEIPVISLEGIDEIEGRRVEICKKIVAACEDWGVFQVVDHGVDAGVIADMTRLAREFFSLPPEDKLRFDMSGGKKGGFIVSSHLQGEAVQDWREIVTYFSYPIRARDYSRWPDKPEDWRSVTEKYSETLMELACKLLGVLSEAMGLDTEAITKACIDMDQKVVVNFYPKCPQPDLTLGLKRHTDPGTITLLLQDQVGGLQATKDGGKTWITVQPVEGAFVVNLGDHGHFLSNGRFKNADHQAVVNSNTSRLSIATFQNPAPDAIVYPLAIREGEKPVLDEPITFAEMYRRKMSRDLELAKIKKLAKVENQEVLEKTKVEAVAQPKGLGEILA",
    "output": "Catalyzes the 3-beta-hydroxylation of (2S)-flavanones to 2R,3R-dihydroflavonols, which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants . Can act on naringenin to produce dihydrokaempferol, and on eriodictyol to produced dihydroquercetin ."
  },
  {
    "instruction": "Can you provide the functional description of the following protein sequence?",
    "input": "MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPEAAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPAYGVGLNPYGYNAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGIPQSNSGVSTLHGIRAW",
    "output": "Transcription factor required for the development of the heart and the spleen . During heart development, acts as a transcriptional activator of NPPA/ANF in cooperation with GATA4 (By similarity). May cooperate with TBX2 to negatively modulate expression of NPPA/ANF in the atrioventricular canal (By similarity). Binds to the core DNA motif of NPPA promoter . Together with PBX1, required for spleen development through a mechanism that involves CDKN2B repression . Positively regulates transcription of genes such as COL3A1 and MMP2, resulting in increased pulmonary endothelial fibrosis in response to hypoxia ."
  },
  {
    "instruction": "Predict the functional description of the protein sequence below.",
    "input": "MTVTVRFAPSPTGYIHIGNTRTALSNWLYASKNNGKFILRYDDTDVERSKDEYAQAIAVDLDWLGVRPDRVEYQSKRFDIYAKAVEKLKTAGLLYACYETADELERRRKLRLARRWPPVYGREALKLTDAEKAALEAEGRKPHWRFLLPNFESDPFATQRTEVHWDDLVRGPQTVDLASMSDPILVREDGTYLYTLPSVVDDIDMGVTHIIRGDDHVTNTGVQISIFKALGATPPVFGHHNLLTTISGEGLSKRTGALSVGSLREAGYEPMAVASLAILIGTSESVTAAPDMAALAEHFDLASISKSSAKFDPSELDALNRSLLHEMPFEKAKPRLEALGICGAKAESFWLAVHGNLDRFSDVSHWWQVVSGDLPEAPDLSGEDRDFVRHAFDLLPPEPWNGQTWKSWTEAVKSATGRKGKNLFMPLRLALTGQAHGPELADLLVLVGLERTKSRRP",
    "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."
  }
]