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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
9487-GP1 | GP1 | 9487 | PIGL | [
"CHIME"
] | [
"KEGG:hsa01100",
"REACT:R-HSA-392499",
"REACT:R-HSA-597592"
] | [
"Metabolic pathways",
"Metabolism of proteins",
"Post-translational protein modification"
] | [] | [
[],
[],
[]
] | Metabolic pathways | Interferon gamma signaling | Propionyl-CoA catabolism | Autophagy - other | 0 |
|
353274-GP1 | GP1 | 353274 | ZNF445 | [
"zinc finger protein 445",
"ZFP445",
"ZKSCAN15",
"ZNF168",
"ZSCAN47",
"zinc finger protein 445",
"zinc finger protein 168"
] | [
"REACT:R-HSA-74160",
"REACT:R-HSA-212436"
] | [
"Gene Expression",
"Generic Transcription Pathway"
] | [] | [
[],
[]
] | Protein methylation | Viral Messenger RNA Synthesis | Pre-NOTCH Expression and Processing | Gene Expression | 3 |
|
112-GP1 | GP1 | 112 | ADCY6 | [
"adenylate cyclase 6",
"AC6",
"LCCS8",
"adenylate cyclase type 6",
"adenylate cyclase type VI"
] | [
"REACT:R-HSA-991365",
"REACT:R-HSA-170660",
"REACT:R-HSA-170670",
"KEGG:hsa04261",
"KEGG:hsa04925",
"KEGG:hsa04371",
"REACT:R-HSA-445717",
"KEGG:hsa04976",
"REACT:R-HSA-111996",
"REACT:R-HSA-111933",
"REACT:R-HSA-111997",
"KEGG:hsa_M00695",
"KEGG:hsa04024",
"KEGG:hsa04022",
"KEGG:hsa04062",
"KEGG:hsa04725",
"KEGG:hsa04713",
"REACT:R-HSA-1489509",
"REACT:R-HSA-2172127",
"REACT:R-HSA-2424491",
"KEGG:hsa05414",
"REACT:R-HSA-186763",
"KEGG:hsa01522",
"KEGG:hsa04915",
"REACT:R-HSA-977444",
"KEGG:hsa04727",
"REACT:R-HSA-977443",
"REACT:R-HSA-418594",
"REACT:R-HSA-418555",
"REACT:R-HSA-418597",
"KEGG:hsa04540",
"KEGG:hsa04971",
"REACT:R-HSA-163359",
"KEGG:hsa04724",
"KEGG:hsa04912",
"REACT:R-HSA-388396",
"REACT:R-HSA-112040",
"REACT:R-HSA-5610787",
"KEGG:hsa05166",
"REACT:R-HSA-168256",
"REACT:R-HSA-168249",
"KEGG:hsa04911",
"REACT:R-HSA-163685",
"KEGG:hsa04211",
"KEGG:hsa04213",
"KEGG:hsa04916",
"REACT:R-HSA-1430728",
"KEGG:hsa05032",
"REACT:R-HSA-112316",
"KEGG:hsa04114",
"REACT:R-HSA-111885",
"KEGG:hsa04913",
"KEGG:hsa04921",
"KEGG:hsa04972",
"KEGG:hsa05200",
"KEGG:hsa04072",
"REACT:R-HSA-163615",
"REACT:R-HSA-164378",
"KEGG:hsa04611",
"REACT:R-HSA-112043",
"REACT:R-HSA-167021",
"KEGG:hsa00230",
"KEGG:hsa04015",
"REACT:R-HSA-422356",
"KEGG:hsa04923",
"KEGG:hsa04924",
"KEGG:hsa04723",
"KEGG:hsa04970",
"REACT:R-HSA-177929",
"REACT:R-HSA-372790",
"REACT:R-HSA-5358351",
"REACT:R-HSA-186797",
"REACT:R-HSA-166520",
"REACT:R-HSA-162582",
"KEGG:hsa04742",
"KEGG:hsa04918",
"REACT:R-HSA-382551",
"REACT:R-HSA-112315",
"KEGG:hsa04270"
] | [
"Activation of GABAB receptors",
"Adenylate cyclase activating pathway",
"Adenylate cyclase inhibitory pathway",
"Adrenergic signaling in cardiomyocytes",
"Aldosterone synthesis and secretion",
"Apelin signaling pathway",
"Aquaporin-mediated transport",
"Bile secretion",
"Ca-dependent events",
"Calmodulin induced events",
"CaM pathway",
"cAMP signaling",
"cAMP signaling pathway",
"cGMP-PKG signaling pathway",
"Chemokine signaling pathway",
"Cholinergic synapse",
"Circadian entrainment",
"DAG and IP3 signaling",
"DAP12 interactions",
"DAP12 signaling",
"Dilated cardiomyopathy",
"Downstream signal transduction",
"Endocrine resistance",
"Estrogen signaling pathway",
"GABA B receptor activation",
"GABAergic synapse",
"GABA receptor activation",
"G alpha (i) signalling events",
"G alpha (s) signalling events",
"G alpha (z) signalling events",
"Gap junction",
"Gastric acid secretion",
"Glucagon signaling in metabolic regulation",
"Glutamatergic synapse",
"GnRH signaling pathway",
"GPCR downstream signaling",
"G-protein mediated events",
"Hedgehog 'off' state",
"HTLV-I infection",
"Immune System",
"Innate Immune System",
"Insulin secretion",
"Integration of energy metabolism",
"Longevity regulating pathway",
"Longevity regulating pathway - multiple species",
"Melanogenesis",
"Metabolism",
"Morphine addiction",
"Neuronal System",
"Oocyte meiosis",
"Opioid Signalling",
"Ovarian steroidogenesis",
"Oxytocin signaling pathway",
"Pancreatic secretion",
"Pathways in cancer",
"Phospholipase D signaling pathway",
"PKA activation",
"PKA activation in glucagon signalling",
"Platelet activation",
"PLC beta mediated events",
"PLC-gamma1 signalling",
"Purine metabolism",
"Rap1 signaling pathway",
"Regulation of insulin secretion",
"Regulation of lipolysis in adipocytes",
"Renin secretion",
"Retrograde endocannabinoid signaling",
"Salivary secretion",
"Signaling by EGFR",
"Signaling by GPCR",
"Signaling by Hedgehog",
"Signaling by PDGF",
"Signalling by NGF",
"Signal Transduction",
"Taste transduction",
"Thyroid hormone synthesis",
"Transmembrane transport of small molecules",
"Transmission across Chemical Synapses",
"Vascular smooth muscle contraction"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Signaling by moderate kinase activity BRAF mutants | Signaling by Interleukins | Gastric acid secretion | Activation of GABAB receptors | 3 |
|
5789-GP1 | GP1 | 5789 | PTPRD | [
"HPTP",
"HPTPD",
"HPTPDELTA",
"PTPD",
"R-PTP-delta",
"RPTPDELTA"
] | [
"REACT:R-HSA-112316",
"REACT:R-HSA-6794362",
"REACT:R-HSA-8849932"
] | [
"Neuronal System",
"Protein-protein interactions at synapses",
"SALM protein interactions at the synapses"
] | [] | [
[],
[],
[]
] | Neuronal System | Neurofascin interactions | Survival motor neuron (SMN) complex | Retrograde endocannabinoid signaling | 0 |
|
79602-GP1 | GP1 | 79602 | ADIPOR2 | [
"adiponectin receptor 2",
"ACDCR2",
"PAQR2",
"adiponectin receptor protein 2"
] | [
"KEGG:hsa04920",
"KEGG:hsa04152",
"REACT:R-HSA-163685",
"KEGG:hsa04211",
"REACT:R-HSA-1430728"
] | [
"Adipocytokine signaling pathway",
"AMPK signaling pathway",
"Integration of energy metabolism",
"Longevity regulating pathway",
"Metabolism"
] | [] | [
[],
[],
[],
[],
[]
] | Adipocytokine signaling pathway | Antimicrobial peptides | Histidine metabolism | Olfactory Signaling Pathway | 0 |
|
366-GP1 | GP1 | 366 | AQP9 | [
"aquaporin 9",
"HsT17287",
"SSC1",
"T17287",
"aquaporin-9",
"aquaglyceroporin-9",
"small solute channel 1"
] | [
"REACT:R-HSA-445717",
"KEGG:hsa04976",
"REACT:R-HSA-432047",
"REACT:R-HSA-382551"
] | [
"Aquaporin-mediated transport",
"Bile secretion",
"Passive transport by Aquaporins",
"Transmembrane transport of small molecules"
] | [] | [
[],
[],
[],
[]
] | Ovarian steroidogenesis | SUMOylation of transcription factors | Aquaporin-mediated transport | Dectin-2 family | 2 |
|
4171-GP1 | GP1 | 4171 | MCM2 | [
"minichromosome maintenance complex component 2",
"BM28",
"CCNL1",
"CDCL1",
"D3S3194",
"DFNA70",
"MITOTIN",
"cdc19",
"DNA replication licensing factor MCM2",
"cell devision cycle-like 1",
"cyclin-like 1",
"nuclear protein BM28"
] | [
"REACT:R-HSA-176187",
"REACT:R-HSA-68962",
"REACT:R-HSA-68867",
"KEGG:hsa04110",
"REACT:R-HSA-1640170",
"REACT:R-HSA-69620",
"REACT:R-HSA-69278",
"REACT:R-HSA-69002",
"REACT:R-HSA-69190",
"REACT:R-HSA-69206",
"REACT:R-HSA-69481",
"KEGG:hsa_M00285",
"REACT:R-HSA-68874",
"REACT:R-HSA-68949",
"REACT:R-HSA-69304",
"REACT:R-HSA-69300",
"REACT:R-HSA-69242",
"REACT:R-HSA-69239",
"REACT:R-HSA-176974"
] | [
"Activation of ATR in response to replication stress",
"Activation of the pre-replicative complex",
"Assembly of the pre-replicative complex",
"Cell cycle",
"Cell Cycle",
"Cell Cycle Checkpoints",
"Cell Cycle, Mitotic",
"DNA Replication Pre-Initiation",
"DNA strand elongation",
"G1/S Transition",
"G2/M Checkpoints",
"MCM complex",
"M/G1 Transition",
"Orc1 removal from chromatin",
"Regulation of DNA replication",
"Removal of licensing factors from origins",
"S Phase",
"Synthesis of DNA",
"Unwinding of DNA"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Heparan sulfate degradation | Activation of ATR in response to replication stress | Insulin signaling pathway | Eukaryotic Translation Elongation | 1 |
|
9055-GP1 | GP1 | 9055 | PRC1 | [
"protein regulator of cytokinesis 1",
"ASE1",
"protein regulator of cytokinesis 1",
"protein regulating cytokinesis 1"
] | [
"REACT:R-HSA-195258",
"REACT:R-HSA-5625900",
"REACT:R-HSA-194315",
"REACT:R-HSA-162582"
] | [
"RHO GTPase Effectors",
"RHO GTPases activate CIT",
"Signaling by Rho GTPases",
"Signal Transduction"
] | [] | [
[],
[],
[],
[]
] | Nuclear signaling by ERBB4 | PI3K events in ERBB2 signaling | Passive transport by Aquaporins | RHO GTPase Effectors | 3 |
|
5208-GP1 | GP1 | 5208 | PFKFB2 | [
"PFK/FBPase 2",
"PFKFB, cardiac"
] | [
"KEGG:hsa04152",
"KEGG:hsa00051",
"REACT:R-HSA-70326",
"REACT:R-HSA-70171",
"REACT:R-HSA-1430728",
"REACT:R-HSA-71387",
"KEGG:hsa04919"
] | [
"AMPK signaling pathway",
"Fructose and mannose metabolism",
"Glucose metabolism",
"Glycolysis",
"Metabolism",
"Metabolism of carbohydrates",
"Thyroid hormone signaling pathway"
] | [] | [
[],
[],
[],
[],
[],
[],
[]
] | Tie2 Signaling | Signal Transduction | Signaling by FGFR | AMPK signaling pathway | 3 |
|
200132-GP1 | GP1 | 200132 | DYNLT5 | [
"TCTEX1D1",
"Tctex1 domain containing 1",
"tctex1 domain-containing protein 1"
] | [
"REACT:R-HSA-5617833",
"REACT:R-HSA-5620924",
"REACT:R-HSA-1852241"
] | [
"Cilium Assembly",
"Intraflagellar transport",
"Organelle biogenesis and maintenance"
] | [] | [
[],
[],
[]
] | Cell-cell junction organization | Cilium Assembly | DNA-PK complex | Golgi Associated Vesicle Biogenesis | 1 |
|
415117-GP1 | GP1 | 415117 | STX19 | [
"syntaxin 19",
"syntaxin-19"
] | [
"KEGG:hsa04130"
] | [
"SNARE interactions in vesicular transport"
] | [] | [
[]
] | Choline metabolism in cancer | EPH-Ephrin signaling | Organelle biogenesis and maintenance | SNARE interactions in vesicular transport | 3 |
|
57162-GP1 | GP1 | 57162 | PELI1 | [
"pellino homolog 1",
"pellino-1",
"protein pellino homolog 1"
] | [
"REACT:R-HSA-166054",
"REACT:R-HSA-1280215",
"REACT:R-HSA-168256",
"REACT:R-HSA-168249",
"REACT:R-HSA-446652",
"REACT:R-HSA-937039",
"REACT:R-HSA-449147",
"REACT:R-HSA-168898"
] | [
"Activated TLR4 signalling",
"Cytokine Signaling in Immune system",
"Immune System",
"Innate Immune System",
"Interleukin-1 signaling",
"IRAK1 recruits IKK complex",
"Signaling by Interleukins",
"Toll-Like Receptors Cascades"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[]
] | Regulation of Apoptosis | SMAC binds to IAPs | Regulation by c-FLIP | Activated TLR4 signalling | 3 |
|
124446-GP1 | GP1 | 124446 | TMEM219 | [
"transmembrane protein 219",
"IGFBP-3R",
"insulin-like growth factor-binding protein 3 receptor",
"testicular tissue protein Li 203"
] | [
"REACT:R-HSA-74160",
"REACT:R-HSA-212436",
"REACT:R-HSA-3700989"
] | [
"Gene Expression",
"Generic Transcription Pathway",
"Transcriptional Regulation by TP53"
] | [] | [
[],
[],
[]
] | Protein methylation | Viral Messenger RNA Synthesis | Gene Expression | Pre-NOTCH Expression and Processing | 2 |
|
2917-GP1 | GP1 | 2917 | GRM7 | [
"glutamate metabotropic receptor 7",
"GLUR7",
"GPRC1G",
"MGLU7",
"MGLUR7",
"NEDSHBA",
"PPP1R87",
"metabotropic glutamate receptor 7",
"glutamate receptor, metabotropic 7",
"protein phosphatase 1, regulatory subunit 87"
] | [
"REACT:R-HSA-418594",
"KEGG:hsa04724",
"REACT:R-HSA-388396",
"REACT:R-HSA-500792",
"KEGG:hsa04080",
"KEGG:hsa04072",
"REACT:R-HSA-372790",
"REACT:R-HSA-162582"
] | [
"G alpha (i) signalling events",
"Glutamatergic synapse",
"GPCR downstream signaling",
"GPCR ligand binding",
"Neuroactive ligand-receptor interaction",
"Phospholipase D signaling pathway",
"Signaling by GPCR",
"Signal Transduction"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[]
] | Wnt signaling | G alpha (i) signalling events | Renin secretion | NoRC negatively regulates rRNA expression | 1 |
|
9690-GP1 | GP1 | 9690 | UBE3C | [
"HECTH2"
] | [
"REACT:R-HSA-1280218",
"REACT:R-HSA-983169",
"REACT:R-HSA-168256",
"KEGG:hsa04120"
] | [
"Adaptive Immune System",
"Class I MHC mediated antigen processing & presentation",
"Immune System",
"Ubiquitin mediated proteolysis"
] | [] | [
[],
[],
[],
[]
] | Adaptive Immune System | Olfactory transduction | Generic Transcription Pathway | Cellular Senescence | 0 |
|
90480-GP1 | GP1 | 90480 | GADD45GIP1 | [
"GADD45G interacting protein 1",
"CKBBP2",
"CKbetaBP2",
"CRIF1",
"MRP-L59",
"PLINP",
"PLINP-1",
"PRG6",
"Plinp1",
"CKII beta binding protein 2",
"CKII beta-associating protein",
"CR6 interacting factor 1",
"mitochondrial large ribosomal subunit protein CRIF1",
"mitochondrial large ribosomal subunit protein mL64",
"p53-responsive gene 6 protein"
] | [
"REACT:R-HSA-5368287",
"REACT:R-HSA-5389840",
"REACT:R-HSA-5368286",
"REACT:R-HSA-5419276",
"REACT:R-HSA-1852241"
] | [
"Mitochondrial translation",
"Mitochondrial translation elongation",
"Mitochondrial translation initiation",
"Mitochondrial translation termination",
"Organelle biogenesis and maintenance"
] | [] | [
[],
[],
[],
[],
[]
] | Mitochondrial translation | RNA polymerase I, eukaryotes | Respiratory electron transport | Cardiac muscle contraction | 0 |
|
100302263-GP1 | GP1 | 100302263 | MIR1908 | [
"microRNA 1908",
"MIRN1908",
"hsa-mir-1908"
] | [
"REACT:R-HSA-2046105",
"REACT:R-HSA-1430728",
"REACT:R-HSA-1989781"
] | [
"Linoleic acid (LA) metabolism",
"Metabolism",
"PPARA activates gene expression"
] | [] | [
[],
[],
[]
] | Interleukin-10 signaling | Heme biosynthesis | Keratan sulfate biosynthesis | Linoleic acid (LA) metabolism | 3 |
|
6369-GP1 | GP1 | 6369 | CCL24 | [
"Ckb-6",
"MPIF-2",
"MPIF2",
"SCYA24",
"C-C motif chemokine 24",
"CK-beta-6",
"eotaxin-2",
"myeloid progenitor inhibitory factor 2"
] | [
"KEGG:hsa04062",
"KEGG:hsa04060"
] | [
"Chemokine signaling pathway",
"Cytokine-cytokine receptor interaction"
] | [] | [
[],
[]
] | VEGFR2 mediated cell proliferation | Chemokine signaling pathway | Glucose metabolism | Glutathione metabolism | 1 |
|
51070-GP1 | GP1 | 51070 | NOSIP | [
"nitric oxide synthase interacting protein",
"CGI-25",
"nitric oxide synthase-interacting protein",
"eNOS-interacting protein"
] | [
"REACT:R-HSA-203765",
"REACT:R-HSA-1430728",
"REACT:R-HSA-202131",
"REACT:R-HSA-203754"
] | [
"eNOS activation and regulation",
"Metabolism",
"Metabolism of nitric oxide",
"NOSIP mediated eNOS trafficking"
] | [] | [
[],
[],
[],
[]
] | eNOS activation and regulation | The IPAF inflammasome | Insulin receptor recycling | N-glycan precursor biosynthesis | 0 |
|
285242-GP1 | GP1 | 285242 | HTR3E | [
"5-HT3-E",
"5-HT3E",
"5-HT3c1"
] | [
"REACT:R-HSA-983712",
"REACT:R-HSA-975298",
"KEGG:hsa04726",
"KEGG:hsa04742",
"REACT:R-HSA-382551"
] | [
"Ion channel transport",
"Ligand-gated ion channel transport",
"Serotonergic synapse",
"Taste transduction",
"Transmembrane transport of small molecules"
] | [] | [
[],
[],
[],
[],
[]
] | Semaphorin interactions | Metabolism of nitric oxide | Terminal pathway of complement | Ion channel transport | 3 |
|
8673-GP1 | GP1 | 8673 | VAMP8 | [
"vesicle associated membrane protein 8",
"EDB",
"vesicle-associated membrane protein 8"
] | [
"REACT:R-HSA-1280218",
"REACT:R-HSA-1236975",
"KEGG:hsa04140",
"REACT:R-HSA-983169",
"REACT:R-HSA-8856828",
"REACT:R-HSA-1236974",
"REACT:R-HSA-432722",
"REACT:R-HSA-168256",
"REACT:R-HSA-168249",
"REACT:R-HSA-432720",
"REACT:R-HSA-199991",
"REACT:R-HSA-6798695",
"KEGG:hsa04611",
"KEGG:hsa04130",
"REACT:R-HSA-5653656"
] | [
"Adaptive Immune System",
"Antigen processing-Cross presentation",
"Autophagy - animal",
"Class I MHC mediated antigen processing & presentation",
"Clathrin-mediated endocytosis",
"ER-Phagosome pathway",
"Golgi Associated Vesicle Biogenesis",
"Immune System",
"Innate Immune System",
"Lysosome Vesicle Biogenesis",
"Membrane Trafficking",
"Neutrophil degranulation",
"Platelet activation",
"SNARE interactions in vesicular transport",
"Vesicle-mediated transport"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Olfactory transduction | Cellular Senescence | Generic Transcription Pathway | Adaptive Immune System | 3 |
|
54904-GP1 | GP1 | 54904 | NSD3 | [
"nuclear receptor binding SET domain protein 3",
"KMT3F",
"KMT3G",
"WHISTLE",
"WHSC1L1",
"pp14328",
"nuclear SET domain-containing protein 3",
"protein whistle"
] | [
"REACT:R-HSA-3247509",
"REACT:R-HSA-4839726",
"KEGG:hsa00310"
] | [
"Chromatin modifying enzymes",
"Chromatin organization",
"Lysine degradation"
] | [] | [
[],
[],
[]
] | Thyroid hormone signaling pathway | Exon junction complex (EJC) | Chromatin modifying enzymes | MHC class II antigen presentation | 2 |
|
2892-GP1 | GP1 | 2892 | GRIA3 | [
"GLUR-C",
"GLUR-K3",
"GLUR3",
"GLURC",
"GluA3",
"MRX94",
"MRXSW",
"glutamate receptor 3",
"AMPA-selective glutamate receptor 3",
"dJ1171F9.1",
"gluR-3",
"glutamate receptor C",
"glutamate receptor subunit 3"
] | [
"REACT:R-HSA-399710",
"KEGG:hsa05031",
"KEGG:hsa04024",
"KEGG:hsa04713",
"KEGG:hsa04728",
"KEGG:hsa04724",
"KEGG:hsa04730",
"KEGG:hsa04080",
"REACT:R-HSA-112316",
"KEGG:hsa05033",
"REACT:R-HSA-6794362",
"KEGG:hsa04723",
"REACT:R-HSA-8849932",
"REACT:R-HSA-399719",
"KEGG:hsa05202",
"REACT:R-HSA-112315"
] | [
"Activation of AMPA receptors",
"Amphetamine addiction",
"cAMP signaling pathway",
"Circadian entrainment",
"Dopaminergic synapse",
"Glutamatergic synapse",
"Long-term depression",
"Neuroactive ligand-receptor interaction",
"Neuronal System",
"Nicotine addiction",
"Protein-protein interactions at synapses",
"Retrograde endocannabinoid signaling",
"SALM protein interactions at the synapses",
"Trafficking of AMPA receptors",
"Transcriptional misregulation in cancer",
"Transmission across Chemical Synapses"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Activation of AMPA receptors | Inositol transporters | Interactions of Vpr with host cellular proteins | DNA-PK complex | 0 |
|
55327-GP1 | GP1 | 55327 | LIN7C | [
"MALS-3",
"MALS3",
"VELI3",
"protein lin-7 homolog C",
"LIN-7 protein 3",
"mammalian lin-seven protein 3",
"veli-3"
] | [
"REACT:R-HSA-112316",
"REACT:R-HSA-112310",
"REACT:R-HSA-6794362",
"REACT:R-HSA-112315"
] | [
"Neuronal System",
"Neurotransmitter Release Cycle",
"Protein-protein interactions at synapses",
"Transmission across Chemical Synapses"
] | [] | [
[],
[],
[],
[]
] | Retrograde endocannabinoid signaling | Survival motor neuron (SMN) complex | Neurofascin interactions | Neuronal System | 3 |
|
407018-GP1 | GP1 | 407018 | MIR27A | [
"microRNA 27a",
"MIRN27A",
"hsa-mir-27a"
] | [
"KEGG:hsa05206"
] | [
"MicroRNAs in cancer"
] | [] | [
[]
] | Cytokine-cytokine receptor interaction | Vesicle-mediated transport | Negative regulation of MAPK pathway | MicroRNAs in cancer | 3 |
|
4249-GP1 | GP1 | 4249 | MGAT5 | [
"GNT-V",
"GNT-VA",
"MGAT5A",
"glcNAc-T V"
] | [
"KEGG:hsa01100",
"REACT:R-HSA-392499",
"REACT:R-HSA-975577",
"KEGG:hsa00510",
"REACT:R-HSA-597592",
"REACT:R-HSA-948021"
] | [
"Metabolic pathways",
"Metabolism of proteins",
"N-Glycan antennae elongation",
"N-Glycan biosynthesis",
"Post-translational protein modification",
"Transport to the Golgi and subsequent modification"
] | [] | [
[],
[],
[],
[],
[],
[]
] | Interferon gamma signaling | Autophagy - other | Metabolic pathways | Propionyl-CoA catabolism | 2 |
|
26523-GP1 | GP1 | 26523 | AGO1 | [
"argonaute RISC component 1",
"EIF2C",
"EIF2C1",
"GERP95",
"Q99",
"hAgo1",
"protein argonaute-1",
"argonaute1",
"eIF-2C 1",
"eIF2C 1",
"putative RNA-binding protein Q99"
] | [
"REACT:R-HSA-1280218",
"REACT:R-HSA-3858494",
"REACT:R-HSA-4086398",
"REACT:R-HSA-2262752",
"REACT:R-HSA-2559583",
"REACT:R-HSA-2172127",
"REACT:R-HSA-2424491",
"REACT:R-HSA-186763",
"REACT:R-HSA-180292",
"REACT:R-HSA-74160",
"REACT:R-HSA-212436",
"REACT:R-HSA-211000",
"REACT:R-HSA-168256",
"REACT:R-HSA-168249",
"REACT:R-HSA-5687128",
"REACT:R-HSA-5683057",
"REACT:R-HSA-203927",
"REACT:R-HSA-2559585",
"REACT:R-HSA-198203",
"REACT:R-HSA-1257604",
"REACT:R-HSA-1912422",
"REACT:R-HSA-1912408",
"REACT:R-HSA-177929",
"REACT:R-HSA-157118",
"REACT:R-HSA-186797",
"REACT:R-HSA-1433557",
"REACT:R-HSA-195721",
"REACT:R-HSA-166520",
"REACT:R-HSA-162582",
"REACT:R-HSA-426486",
"REACT:R-HSA-5628897",
"REACT:R-HSA-5578749",
"REACT:R-HSA-3700989"
] | [
"Adaptive Immune System",
"Beta-catenin independent WNT signaling",
"Ca2+ pathway",
"Cellular responses to stress",
"Cellular Senescence",
"DAP12 interactions",
"DAP12 signaling",
"Downstream signal transduction",
"GAB1 signalosome",
"Gene Expression",
"Generic Transcription Pathway",
"Gene Silencing by RNA",
"Immune System",
"Innate Immune System",
"MAPK6/MAPK4 signaling",
"MAPK family signaling cascades",
"MicroRNA (miRNA) biogenesis",
"Oncogene Induced Senescence",
"PI3K/AKT activation",
"PIP3 activates AKT signaling",
"Pre-NOTCH Expression and Processing",
"Pre-NOTCH Transcription and Translation",
"Signaling by EGFR",
"Signaling by NOTCH",
"Signaling by PDGF",
"Signaling by SCF-KIT",
"Signaling by Wnt",
"Signalling by NGF",
"Signal Transduction",
"Small interfering RNA (siRNA) biogenesis",
"TP53 Regulates Metabolic Genes",
"Transcriptional regulation by small RNAs",
"Transcriptional Regulation by TP53"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Generic Transcription Pathway | Cellular Senescence | Olfactory transduction | Adaptive Immune System | 3 |
|
340267-GP1 | GP1 | 340267 | COL28A1 | [] | [
"REACT:R-HSA-8948216",
"REACT:R-HSA-1474290",
"REACT:R-HSA-1474244"
] | [
"Collagen chain trimerization",
"Collagen formation",
"Extracellular matrix organization"
] | [] | [
[],
[],
[]
] | Collagen chain trimerization | Insulin signaling pathway | Synthesis of DNA | RIPK1-mediated regulated necrosis | 0 |
|
27199-GP1 | GP1 | 27199 | OXGR1 | [
"oxoglutarate receptor 1",
"GPR80",
"GPR99",
"P2RY15",
"P2Y15",
"aKGR",
"2-oxoglutarate receptor 1",
"G protein-coupled receptor 80",
"G-protein coupled receptor 99",
"P2Y purinoceptor 15",
"P2Y-like GPCR",
"P2Y-like nucleotide receptor",
"alpha-ketoglutarate receptor 1",
"seven transmembrane helix receptor"
] | [
"REACT:R-HSA-418594",
"REACT:R-HSA-388396",
"REACT:R-HSA-500792",
"REACT:R-HSA-372790",
"REACT:R-HSA-162582"
] | [
"G alpha (i) signalling events",
"GPCR downstream signaling",
"GPCR ligand binding",
"Signaling by GPCR",
"Signal Transduction"
] | [] | [
[],
[],
[],
[],
[]
] | G alpha (i) signalling events | Renin secretion | NoRC negatively regulates rRNA expression | Wnt signaling | 0 |
|
25766-GP1 | GP1 | 25766 | PRPF40B | [
"HYPC",
"Huntingtin interacting protein C",
"huntingtin yeast partner C"
] | [
"KEGG:hsa03040"
] | [
"Spliceosome"
] | [] | [
[]
] | Nucleosome assembly | SNARE interactions in vesicular transport | Spliceosome | tRNA processing in the nucleus | 2 |
|
4342-GP1 | GP1 | 4342 | MOS | [
"MSV",
"c-mos",
"oocyte maturation factor mos",
"proto-oncogene c-Mos"
] | [
"KEGG:hsa04010",
"KEGG:hsa04114",
"KEGG:hsa04810"
] | [
"MAPK signaling pathway",
"Oocyte meiosis",
"Regulation of actin cytoskeleton"
] | [] | [
[],
[],
[]
] | Signaling by NOTCH2 | MAPK signaling pathway | Adipocytokine signaling pathway | Regulation of RAS by GAPs | 1 |
|
57522-GP1 | GP1 | 57522 | SRGAP1 | [
"ARHGAP13",
"NMTC2",
"rho GTPase-activating protein 13"
] | [
"REACT:R-HSA-422475",
"KEGG:hsa04360",
"REACT:R-HSA-1266738",
"REACT:R-HSA-194840",
"REACT:R-HSA-194315",
"REACT:R-HSA-376176",
"REACT:R-HSA-162582"
] | [
"Axon guidance",
"Axon guidance",
"Developmental Biology",
"Rho GTPase cycle",
"Signaling by Rho GTPases",
"Signaling by Robo receptor",
"Signal Transduction"
] | [] | [
[],
[],
[],
[],
[],
[],
[]
] | SHC1 events in ERBB2 signaling | Axon guidance | Carbon metabolism | Laminin interactions | 1 |
|
81539-GP1 | GP1 | 81539 | SLC38A1 | [
"solute carrier family 38 member 1",
"ATA1",
"NAT2",
"SAT1",
"SNAT1",
"sodium-coupled neutral amino acid transporter 1",
"N-system amino acid transporter 2",
"amino acid transporter A1",
"amino acid transporter system A1",
"system A amino acid transporter 1",
"system N amino acid transporter 1"
] | [
"REACT:R-HSA-352230",
"KEGG:hsa04727",
"KEGG:hsa04724",
"REACT:R-HSA-112316",
"REACT:R-HSA-425407",
"REACT:R-HSA-382551",
"REACT:R-HSA-112315"
] | [
"Amino acid transport across the plasma membrane",
"GABAergic synapse",
"Glutamatergic synapse",
"Neuronal System",
"SLC-mediated transmembrane transport",
"Transmembrane transport of small molecules",
"Transmission across Chemical Synapses"
] | [] | [
[],
[],
[],
[],
[],
[],
[]
] | Aldosterone synthesis and secretion | Amino acid transport across the plasma membrane | Integrin cell surface interactions | Galactose metabolism | 1 |
|
2994-GP1 | GP1 | 2994 | GYPB | [
"CD235b",
"GPB",
"GYPA",
"MNS",
"PAS-3",
"SS",
"glycophorin-B",
"GYPB-A fusion",
"GYPB-A-B fusion",
"GYPB/GYPA fusion",
"SS-active sialoglycoprotein",
"Ss blood group",
"glycophorin A",
"glycophorin Hop",
"hybrid glycophorin Kip",
"sialoglycoprotein delta"
] | [
"REACT:R-HSA-202733",
"REACT:R-HSA-109582",
"KEGG:hsa05144"
] | [
"Cell surface interactions at the vascular wall",
"Hemostasis",
"Malaria"
] | [] | [
[],
[],
[]
] | SHC1 events in ERBB4 signaling | Mitochondrial translation initiation | Mitochondrial transcription initiation | Cell surface interactions at the vascular wall | 3 |
|
5743-GP1 | GP1 | 5743 | PTGS2 | [
"COX-2",
"COX2",
"GRIPGHS",
"PGG/HS",
"PGHS-2",
"PHS-2",
"hCox-2",
"PGH synthase 2",
"PHS II",
"cyclooxygenase 2",
"cyclooxygenase 2b"
] | [
"REACT:R-HSA-2142753",
"KEGG:hsa00590",
"KEGG:hsa05204",
"REACT:R-HSA-1280215",
"KEGG:hsa04657",
"REACT:R-HSA-168256",
"REACT:R-HSA-6783783",
"REACT:R-HSA-6785807",
"KEGG:hsa05140",
"KEGG:hsa01100",
"REACT:R-HSA-1430728",
"KEGG:hsa05206",
"KEGG:hsa04064",
"REACT:R-HSA-197264",
"REACT:R-HSA-196807",
"KEGG:hsa04913",
"KEGG:hsa04921",
"KEGG:hsa05200",
"KEGG:hsa04923",
"KEGG:hsa04723",
"KEGG:hsa04726",
"REACT:R-HSA-449147",
"KEGG:hsa05222",
"KEGG:hsa04668",
"KEGG:hsa04370"
] | [
"Arachidonic acid metabolism",
"Arachidonic acid metabolism",
"Chemical carcinogenesis",
"Cytokine Signaling in Immune system",
"IL-17 signaling pathway",
"Immune System",
"Interleukin-10 signaling",
"Interleukin-4 and 13 signaling",
"Leishmaniasis",
"Metabolic pathways",
"Metabolism",
"MicroRNAs in cancer",
"NF-kappa B signaling pathway",
"Nicotinamide salvaging",
"Nicotinate metabolism",
"Ovarian steroidogenesis",
"Oxytocin signaling pathway",
"Pathways in cancer",
"Regulation of lipolysis in adipocytes",
"Retrograde endocannabinoid signaling",
"Serotonergic synapse",
"Signaling by Interleukins",
"Small cell lung cancer",
"TNF signaling pathway",
"VEGF signaling pathway"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Cyclin D associated events in G1 | Signaling by VEGF | Arachidonic acid metabolism | Post NMDA receptor activation events | 2 |
|
219869-GP1 | GP1 | 219869 | OR10G8 | [
"OR11-274",
"OR11-282",
"olfactory receptor 10G8",
"olfactory receptor OR11-282"
] | [
"REACT:R-HSA-388396",
"REACT:R-HSA-381753",
"KEGG:hsa04740",
"REACT:R-HSA-372790",
"REACT:R-HSA-162582"
] | [
"GPCR downstream signaling",
"Olfactory Signaling Pathway",
"Olfactory transduction",
"Signaling by GPCR",
"Signal Transduction"
] | [] | [
[],
[],
[],
[],
[]
] | GPCR downstream signaling | NF-kappa B signaling pathway | Iron uptake and transport | Ubiquitin mediated proteolysis | 0 |
|
285195-GP1 | GP1 | 285195 | SLC9A9 | [
"solute carrier family 9 member A9",
"AUTS16",
"NHE9",
"sodium/hydrogen exchanger 9",
"putative protein product of Nbla00118",
"sodium/proton exchanger NHE9"
] | [
"REACT:R-HSA-425407",
"REACT:R-HSA-425986",
"REACT:R-HSA-382551"
] | [
"SLC-mediated transmembrane transport",
"Sodium/Proton exchangers",
"Transmembrane transport of small molecules"
] | [] | [
[],
[],
[]
] | Activation of AMPA receptors | Signaling by Wnt | SLC-mediated transmembrane transport | Signaling by Rho GTPases | 2 |
|
4604-GP1 | GP1 | 4604 | MYBPC1 | [
"myosin binding protein C1",
"LCCS4",
"MYBPCC",
"MYBPCS",
"MYOTREM",
"ssMyBP-C",
"myosin binding protein C, slow type",
"skeletal muscle C-protein",
"slow MyBP-C"
] | [
"REACT:R-HSA-397014",
"REACT:R-HSA-390522"
] | [
"Muscle contraction",
"Striated Muscle Contraction"
] | [] | [
[],
[]
] | Muscle contraction | Platelet activation | Extracellular matrix organization | Collagen degradation | 0 |
|
1669-GP1 | GP1 | 1669 | DEFA4 | [
"defensin alpha 4",
"DEF4",
"HNP-4",
"HP-4",
"HP4",
"neutrophil defensin 4",
"corticostatin"
] | [
"REACT:R-HSA-1462054",
"REACT:R-HSA-6803157",
"REACT:R-HSA-1461973",
"REACT:R-HSA-168256",
"REACT:R-HSA-168249",
"REACT:R-HSA-6798695"
] | [
"Alpha-defensins",
"Antimicrobial peptides",
"Defensins",
"Immune System",
"Innate Immune System",
"Neutrophil degranulation"
] | [] | [
[],
[],
[],
[],
[],
[]
] | Cocaine addiction | Josephin domain DUBs | Alpha-defensins | Bacterial invasion of epithelial cells | 2 |
|
52-GP1 | GP1 | 52 | ACP1 | [
"acid phosphatase 1",
"HAAP",
"LMW-PTP",
"LMWPTP",
"LMW-PTPase",
"acid phosphatase 1, soluble",
"adipocyte acid phosphatase",
"protein tyrosine phosphatase",
"red cell acid phosphatase 1",
"testicular secretory protein Li 37"
] | [
"KEGG:hsa04520",
"KEGG:hsa01100",
"KEGG:hsa00740",
"KEGG:hsa00730"
] | [
"Adherens junction",
"Metabolic pathways",
"Riboflavin metabolism",
"Thiamine metabolism"
] | [] | [
[],
[],
[],
[]
] | Adherens junction | Glutathione metabolism | Glucose metabolism | Glutathione synthesis and recycling | 0 |
|
27341-GP1 | GP1 | 27341 | RRP7A | [
"ribosomal RNA processing 7 homolog A",
"BK126B4.3",
"CGI-96",
"CTA-126B4.5",
"gastric cancer antigen Zg14"
] | [
"REACT:R-HSA-74160",
"REACT:R-HSA-72312"
] | [
"Gene Expression",
"rRNA processing"
] | [] | [
[],
[]
] | Pre-NOTCH Expression and Processing | Protein methylation | Gene Expression | Viral Messenger RNA Synthesis | 2 |
|
51028-GP1 | GP1 | 51028 | VPS36 | [
"vacuolar protein sorting 36 homolog",
"C13orf9",
"CGI-145",
"EAP45",
"ELL-associated protein of 45 kDa",
"ESCRT-II complex subunit VPS36"
] | [
"KEGG:hsa04144",
"REACT:R-HSA-199991",
"REACT:R-HSA-5653656"
] | [
"Endocytosis",
"Membrane Trafficking",
"Vesicle-mediated transport"
] | [] | [
[],
[],
[]
] | Vesicle-mediated transport | Regulation of RAS by GAPs | Endocytosis | Chylomicron-mediated lipid transport | 2 |
|
51205-GP1 | GP1 | 51205 | ACP6 | [
"ACPL1",
"LPAP",
"PACPL1",
"acid phosphatase-like protein 1"
] | [
"REACT:R-HSA-1430728",
"REACT:R-HSA-1483257",
"REACT:R-HSA-1483166"
] | [
"Metabolism",
"Phospholipid metabolism",
"Synthesis of PA"
] | [] | [
[],
[],
[]
] | Ceramide biosynthesis | Metabolism | Fatty acid biosynthesis | Metabolism of fat-soluble vitamins | 1 |
|
4091-GP1 | GP1 | 4091 | SMAD6 | [
"SMAD family member 6",
"AOVD2",
"HsT17432",
"MADH6",
"MADH7",
"MAD homolog 6"
] | [
"REACT:R-HSA-201451",
"REACT:R-HSA-162582",
"KEGG:hsa04350"
] | [
"Signaling by BMP",
"Signal Transduction",
"TGF-beta signaling pathway"
] | [] | [
[],
[],
[]
] | FasL/ CD95L signaling | Centrosome maturation | Antigen processing and presentation | Signaling by BMP | 3 |
|
54472-GP1 | GP1 | 54472 | TOLLIP | [
"toll interacting protein",
"IL-1RAcPIP",
"toll-interacting protein",
"adapter protein"
] | [
"REACT:R-HSA-1280215",
"REACT:R-HSA-168256",
"REACT:R-HSA-168249",
"REACT:R-HSA-446652",
"REACT:R-HSA-6798695",
"REACT:R-HSA-449147",
"KEGG:hsa04620"
] | [
"Cytokine Signaling in Immune system",
"Immune System",
"Innate Immune System",
"Interleukin-1 signaling",
"Neutrophil degranulation",
"Signaling by Interleukins",
"Toll-like receptor signaling pathway"
] | [] | [
[],
[],
[],
[],
[],
[],
[]
] | Oncogene Induced Senescence | Cytokine Signaling in Immune system | Signaling by FGFR2 | Signaling by FGFR3 | 1 |
|
79646-GP1 | GP1 | 79646 | PANK3 | [
"pantothenate kinase 3",
"pantothenate kinase 3",
"hPanK3",
"pantothenic acid kinase 3"
] | [
"REACT:R-HSA-196783",
"KEGG:hsa01100",
"REACT:R-HSA-1430728"
] | [
"Coenzyme A biosynthesis",
"Metabolic pathways",
"Metabolism"
] | [] | [
[],
[],
[]
] | Heparan sulfate degradation | Coenzyme A biosynthesis | Regulation of Complement cascade | Transport of nucleotide sugars | 1 |
|
338339-GP1 | GP1 | 338339 | CLEC4D | [
"CD368",
"CLEC-6",
"CLEC6",
"CLECSF8",
"Dectin-3",
"MCL",
"MPCL",
"C-type lectin receptor",
"C-type lectin superfamily member 8",
"C-type lectin-like receptor 6",
"Dectin 3",
"macrophage C-type lectin"
] | [
"REACT:R-HSA-5621480",
"REACT:R-HSA-168256",
"REACT:R-HSA-168249",
"REACT:R-HSA-6798695"
] | [
"Dectin-2 family",
"Immune System",
"Innate Immune System",
"Neutrophil degranulation"
] | [] | [
[],
[],
[],
[]
] | Sodium/Calcium exchangers | Dectin-2 family | Aquaporin-mediated transport | G alpha (s) signalling events | 1 |
|
730394-GP1 | GP1 | 730394 | GTF2H2C_2 | [
"GTF2H2D",
"general transcription factor IIH subunit 2-like protein"
] | [
"KEGG:hsa03022",
"KEGG:hsa_M00290",
"KEGG:hsa03420",
"KEGG:hsa05203"
] | [
"Basal transcription factors",
"Holo-TFIIH complex",
"Nucleotide excision repair",
"Viral carcinogenesis"
] | [] | [
[],
[],
[],
[]
] | Basal transcription factors | PIP3 activates AKT signaling | Elastic fibre formation | Thiamine metabolism | 0 |
|
2774-GP1 | GP1 | 2774 | GNAL | [
"G protein subunit alpha L",
"DYT25"
] | [
"REACT:R-HSA-991365",
"REACT:R-HSA-170660",
"REACT:R-HSA-170670",
"KEGG:hsa05146",
"KEGG:hsa04020",
"KEGG:hsa04728",
"REACT:R-HSA-977444",
"REACT:R-HSA-977443",
"REACT:R-HSA-388396",
"REACT:R-HSA-112040",
"REACT:R-HSA-112316",
"REACT:R-HSA-381753",
"KEGG:hsa04740",
"REACT:R-HSA-111885",
"KEGG:hsa05012",
"REACT:R-HSA-372790",
"REACT:R-HSA-162582",
"REACT:R-HSA-112315"
] | [
"Activation of GABAB receptors",
"Adenylate cyclase activating pathway",
"Adenylate cyclase inhibitory pathway",
"Amoebiasis",
"Calcium signaling pathway",
"Dopaminergic synapse",
"GABA B receptor activation",
"GABA receptor activation",
"GPCR downstream signaling",
"G-protein mediated events",
"Neuronal System",
"Olfactory Signaling Pathway",
"Olfactory transduction",
"Opioid Signalling",
"Parkinson's disease",
"Signaling by GPCR",
"Signal Transduction",
"Transmission across Chemical Synapses"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Signaling by moderate kinase activity BRAF mutants | Gastric acid secretion | Activation of GABAB receptors | Signaling by Interleukins | 2 |
|
6584-GP1 | GP1 | 6584 | SLC22A5 | [
"solute carrier family 22 member 5",
"CDSP",
"OCTN2",
"solute carrier family 22 member 5",
"organic cation/carnitine transporter 2"
] | [
"KEGG:hsa05231",
"REACT:R-HSA-549127",
"REACT:R-HSA-425407",
"REACT:R-HSA-382551"
] | [
"Choline metabolism in cancer",
"Organic cation transport",
"SLC-mediated transmembrane transport",
"Transmembrane transport of small molecules"
] | [] | [
[],
[],
[],
[]
] | Choline metabolism in cancer | Recycling pathway of L1 | Protein-protein interactions at synapses | SNARE interactions in vesicular transport | 0 |
|
608-GP1 | GP1 | 608 | TNFRSF17 | [
"TNF receptor superfamily member 17",
"BCM",
"BCMA",
"CD269",
"TNFRSF13A",
"tumor necrosis factor receptor superfamily member 17",
"B cell maturation antigen",
"B-cell maturation factor",
"B-cell maturation protein"
] | [
"KEGG:hsa04060",
"REACT:R-HSA-1280215",
"REACT:R-HSA-168256",
"KEGG:hsa04672",
"REACT:R-HSA-5669034"
] | [
"Cytokine-cytokine receptor interaction",
"Cytokine Signaling in Immune system",
"Immune System",
"Intestinal immune network for IgA production",
"TNFs bind their physiological receptors"
] | [] | [
[],
[],
[],
[],
[]
] | Folate biosynthesis | Metabolism of nucleotides | Cytokine-cytokine receptor interaction | Arginine biosynthesis | 2 |
|
100528021-GP1 | GP1 | 100528021 | ST20-MTHFS | [
"ST20-MTHFS readthrough",
"ST20-MTHFS protein",
"Methenyl-THF synthetase"
] | [
"KEGG:hsa01100",
"KEGG:hsa00670"
] | [
"Metabolic pathways",
"One carbon pool by folate"
] | [] | [
[],
[]
] | Propionyl-CoA catabolism | Interferon gamma signaling | Metabolic pathways | Autophagy - other | 2 |
|
3581-GP1 | GP1 | 3581 | IL9R | [
"interleukin 9 receptor",
"CD129",
"interleukin-9 receptor",
"IL-9 receptor"
] | [
"KEGG:hsa04060",
"REACT:R-HSA-1280215",
"KEGG:hsa04640",
"REACT:R-HSA-168256",
"KEGG:hsa04630",
"REACT:R-HSA-449147"
] | [
"Cytokine-cytokine receptor interaction",
"Cytokine Signaling in Immune system",
"Hematopoietic cell lineage",
"Immune System",
"Jak-STAT signaling pathway",
"Signaling by Interleukins"
] | [] | [
[],
[],
[],
[],
[],
[]
] | Metabolism of nucleotides | Arginine biosynthesis | Folate biosynthesis | Cytokine-cytokine receptor interaction | 3 |
|
84844-GP1 | GP1 | 84844 | PHF5A | [
"PHD finger protein 5A",
"INI",
"Rds3",
"SAP14b",
"SF3B7",
"SF3b14b",
"bK223H9.2",
"PHD finger-like domain protein 5A",
"PHD-finger 5a",
"splicing factor 3b, subunit 7"
] | [
"REACT:R-HSA-74160",
"REACT:R-HSA-72172",
"REACT:R-HSA-72163",
"KEGG:hsa03040"
] | [
"Gene Expression",
"mRNA Splicing",
"mRNA Splicing - Major Pathway",
"Spliceosome"
] | [] | [
[],
[],
[],
[]
] | Gene Expression | Protein methylation | Viral Messenger RNA Synthesis | Pre-NOTCH Expression and Processing | 0 |
|
160-GP1 | GP1 | 160 | AP2A1 | [
"adaptor related protein complex 2 subunit alpha 1",
"ADTAA",
"AP2-ALPHA",
"CLAPA1",
"AP-2 complex subunit alpha-1",
"100 kDa coated vesicle protein A",
"adaptin, alpha A",
"adaptor related protein complex 2 alpha 1 subunit",
"alpha-adaptin A",
"alpha1-adaptin"
] | [
"REACT:R-HSA-1280218",
"REACT:R-HSA-422475",
"REACT:R-HSA-3858494",
"REACT:R-HSA-8856828",
"REACT:R-HSA-1266738",
"REACT:R-HSA-1643685",
"KEGG:hsa04144",
"REACT:R-HSA-2682334",
"REACT:R-HSA-162906",
"REACT:R-HSA-162909",
"KEGG:hsa05016",
"REACT:R-HSA-168256",
"REACT:R-HSA-5663205",
"REACT:R-HSA-373760",
"REACT:R-HSA-171052",
"REACT:R-HSA-174824",
"REACT:R-HSA-199991",
"REACT:R-HSA-1430728",
"REACT:R-HSA-2132295",
"REACT:R-HSA-167590",
"REACT:R-HSA-182218",
"REACT:R-HSA-112316",
"REACT:R-HSA-4086400",
"REACT:R-HSA-437239",
"REACT:R-HSA-177504",
"REACT:R-HSA-195721",
"REACT:R-HSA-166520",
"REACT:R-HSA-162582",
"KEGG:hsa04721",
"REACT:R-HSA-399719",
"REACT:R-HSA-112315",
"REACT:R-HSA-5653656",
"REACT:R-HSA-8855121",
"REACT:R-HSA-8866427"
] | [
"Adaptive Immune System",
"Axon guidance",
"Beta-catenin independent WNT signaling",
"Clathrin-mediated endocytosis",
"Developmental Biology",
"Disease",
"Endocytosis",
"EPH-Ephrin signaling",
"HIV Infection",
"Host Interactions of HIV factors",
"Huntington's disease",
"Immune System",
"Infectious disease",
"L1CAM interactions",
"LDL-mediated lipid transport",
"Lipoprotein metabolism",
"Membrane Trafficking",
"Metabolism",
"MHC class II antigen presentation",
"Nef Mediated CD4 Down-regulation",
"Nef Mediated CD8 Down-regulation",
"Neuronal System",
"PCP/CE pathway",
"Recycling pathway of L1",
"Retrograde neurotrophin signalling",
"Signaling by Wnt",
"Signalling by NGF",
"Signal Transduction",
"Synaptic vesicle cycle",
"Trafficking of AMPA receptors",
"Transmission across Chemical Synapses",
"Vesicle-mediated transport",
"VLDL interactions",
"VLDLR internalisation and degradation"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Generic Transcription Pathway | Cellular Senescence | Olfactory transduction | Adaptive Immune System | 3 |
|
79001-GP1 | GP1 | 79001 | VKORC1 | [
"EDTP308",
"MST134",
"MST576",
"VKCFD2",
"vitamin K dependent clotting factors deficiency 2"
] | [
"REACT:R-HSA-1430728",
"REACT:R-HSA-6806667",
"REACT:R-HSA-6806664"
] | [
"Metabolism",
"Metabolism of fat-soluble vitamins",
"Metabolism of vitamin K"
] | [] | [
[],
[],
[]
] | Ceramide biosynthesis | Metabolism of fat-soluble vitamins | Metabolism | Fatty acid biosynthesis | 2 |
|
3441-GP1 | GP1 | 3441 | IFNA4 | [
"interferon alpha 4",
"IFN-alpha4a",
"INFA4",
"interferon alpha-4",
"IFN-alpha-4",
"interferon alpha-4B",
"interferon alpha-76",
"interferon alpha-M1"
] | [
"KEGG:hsa05320",
"KEGG:hsa04060",
"REACT:R-HSA-1280215",
"KEGG:hsa04623",
"REACT:R-HSA-109582",
"KEGG:hsa05161",
"KEGG:hsa05160",
"KEGG:hsa05168",
"REACT:R-HSA-168256",
"KEGG:hsa05164",
"REACT:R-HSA-168249",
"REACT:R-HSA-909733",
"REACT:R-HSA-913531",
"KEGG:hsa04630",
"KEGG:hsa05162",
"KEGG:hsa04650",
"KEGG:hsa04621",
"KEGG:hsa04151",
"REACT:R-HSA-912694",
"KEGG:hsa04622",
"KEGG:hsa04620",
"REACT:R-HSA-933541",
"KEGG:hsa05152"
] | [
"Autoimmune thyroid disease",
"Cytokine-cytokine receptor interaction",
"Cytokine Signaling in Immune system",
"Cytosolic DNA-sensing pathway",
"Hemostasis",
"Hepatitis B",
"Hepatitis C",
"Herpes simplex infection",
"Immune System",
"Influenza A",
"Innate Immune System",
"Interferon alpha/beta signaling",
"Interferon Signaling",
"Jak-STAT signaling pathway",
"Measles",
"Natural killer cell mediated cytotoxicity",
"NOD-like receptor signaling pathway",
"PI3K-Akt signaling pathway",
"Regulation of IFNA signaling",
"RIG-I-like receptor signaling pathway",
"Toll-like receptor signaling pathway",
"TRAF6 mediated IRF7 activation",
"Tuberculosis"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Cysteine and methionine metabolism | Cytokine-cytokine receptor interaction | Tyrosine metabolism | Autoimmune thyroid disease | 3 |
|
3770-GP1 | GP1 | 3770 | KCNJ14 | [
"IRK4",
"KIR2.4",
"ATP-sensitive inward rectifier potassium channel 14",
"potassium voltage-gated channel subfamily J member 14"
] | [
"REACT:R-HSA-5576891",
"KEGG:hsa04725",
"REACT:R-HSA-1296053",
"REACT:R-HSA-1296065",
"REACT:R-HSA-397014",
"REACT:R-HSA-112316",
"KEGG:hsa04921",
"REACT:R-HSA-5576886",
"REACT:R-HSA-1296071"
] | [
"Cardiac conduction",
"Cholinergic synapse",
"Classical Kir channels",
"Inwardly rectifying K+ channels",
"Muscle contraction",
"Neuronal System",
"Oxytocin signaling pathway",
"Phase 4 - resting membrane potential",
"Potassium Channels"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Ketone body metabolism | Axon guidance | Cardiac conduction | Axon guidance | 2 |
|
1496-GP1 | GP1 | 1496 | CTNNA2 | [
"catenin alpha 2",
"CAP-R",
"CAPR",
"CDCBM9",
"CT114",
"CTNR",
"catenin alpha-2",
"alpha-N-catenin",
"alpha-catenin-related protein",
"cadherin-associated protein, related",
"cancer/testis antigen 114"
] | [
"KEGG:hsa04520",
"KEGG:hsa05100",
"REACT:R-HSA-375170",
"REACT:R-HSA-1266738",
"KEGG:hsa05213",
"KEGG:hsa04390",
"KEGG:hsa04670",
"REACT:R-HSA-525793",
"KEGG:hsa05200"
] | [
"Adherens junction",
"Bacterial invasion of epithelial cells",
"CDO in myogenesis",
"Developmental Biology",
"Endometrial cancer",
"Hippo signaling pathway",
"Leukocyte transendothelial migration",
"Myogenesis",
"Pathways in cancer"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Glucose metabolism | Glutathione synthesis and recycling | Adherens junction | Glutathione metabolism | 2 |
|
55629-GP1 | GP1 | 55629 | PNRC2 | [
"proline rich nuclear receptor coactivator 2"
] | [
"REACT:R-HSA-74160"
] | [
"Gene Expression"
] | [] | [
[]
] | Pre-NOTCH Expression and Processing | Protein methylation | Viral Messenger RNA Synthesis | Gene Expression | 3 |
|
9821-GP1 | GP1 | 9821 | RB1CC1 | [
"RB1 inducible coiled-coil 1",
"ATG17",
"FIP200",
"PPP1R131",
"phosphatase 1, regulatory subunit 131"
] | [
"KEGG:hsa04140",
"REACT:R-HSA-2262752",
"KEGG:hsa04211",
"REACT:R-HSA-1632852"
] | [
"Autophagy - animal",
"Cellular responses to stress",
"Longevity regulating pathway",
"Macroautophagy"
] | [] | [
[],
[],
[],
[]
] | Synaptic vesicle cycle | Autophagy - animal | Mineral absorption | GRB2 events in EGFR signaling | 1 |
|
51129-GP1 | GP1 | 51129 | ANGPTL4 | [
"angiopoietin like 4",
"ARP4",
"FIAF",
"HARP",
"HFARP",
"NL2",
"PGAR",
"TGQTL",
"UNQ171",
"pp1158",
"angiopoietin-related protein 4",
"PPARG angiopoietin related protein",
"fasting-induced adipose factor"
] | [
"REACT:R-HSA-174800",
"REACT:R-HSA-1266738",
"REACT:R-HSA-174824",
"REACT:R-HSA-1430728",
"REACT:R-HSA-1989781",
"KEGG:hsa03320"
] | [
"Chylomicron-mediated lipid transport",
"Developmental Biology",
"Lipoprotein metabolism",
"Metabolism",
"PPARA activates gene expression",
"PPAR signaling pathway"
] | [] | [
[],
[],
[],
[],
[],
[]
] | BER complex | Chylomicron-mediated lipid transport | Stimuli-sensing channels | SMAC-mediated apoptotic response | 1 |
|
1121-GP1 | GP1 | 1121 | CHM | [
"CHM Rab escort protein",
"DXS540",
"GGTA",
"HSD-32",
"REP-1",
"TCD",
"CHM, Rab escort protein 1"
] | [
"REACT:R-HSA-74160",
"REACT:R-HSA-212436",
"REACT:R-HSA-199991",
"REACT:R-HSA-392499",
"REACT:R-HSA-597592",
"REACT:R-HSA-8873719",
"REACT:R-HSA-3700989",
"REACT:R-HSA-5653656"
] | [
"Gene Expression",
"Generic Transcription Pathway",
"Membrane Trafficking",
"Metabolism of proteins",
"Post-translational protein modification",
"RAB geranylgeranylation",
"Transcriptional Regulation by TP53",
"Vesicle-mediated transport"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[]
] | Pre-NOTCH Expression and Processing | Viral Messenger RNA Synthesis | Gene Expression | Protein methylation | 2 |
|
92283-GP1 | GP1 | 92283 | ZNF461 | [
"zinc finger protein 461",
"GIOT-1",
"GIOT1",
"HZF28",
"zinc finger protein 461",
"zinc finger protein 28"
] | [
"REACT:R-HSA-74160",
"REACT:R-HSA-212436"
] | [
"Gene Expression",
"Generic Transcription Pathway"
] | [] | [
[],
[]
] | Protein methylation | Pre-NOTCH Expression and Processing | Viral Messenger RNA Synthesis | Gene Expression | 3 |
|
58484-GP1 | GP1 | 58484 | NLRC4 | [
"NLR family CARD domain containing 4",
"AIFEC",
"CARD12",
"CLAN",
"CLAN1",
"CLANA",
"CLANB",
"CLANC",
"CLAND",
"CLR2.1",
"FCAS4",
"IPAF",
"NLR family CARD domain-containing protein 4",
"ICE-protease activating factor",
"NOD-like receptor C4",
"caspase recruitment domain family, member 12",
"caspase recruitment domain-containing protein 12"
] | [
"REACT:R-HSA-74160",
"REACT:R-HSA-212436",
"REACT:R-HSA-168256",
"REACT:R-HSA-622312",
"REACT:R-HSA-168249",
"KEGG:hsa05134",
"KEGG:hsa04621",
"KEGG:hsa05132",
"REACT:R-HSA-844623",
"REACT:R-HSA-3700989"
] | [
"Gene Expression",
"Generic Transcription Pathway",
"Immune System",
"Inflammasomes",
"Innate Immune System",
"Legionellosis",
"NOD-like receptor signaling pathway",
"Salmonella infection",
"The IPAF inflammasome",
"Transcriptional Regulation by TP53"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Protein methylation | Pre-NOTCH Expression and Processing | Gene Expression | Viral Messenger RNA Synthesis | 2 |
|
66005-GP1 | GP1 | 66005 | CHID1 | [
"chitinase domain containing 1",
"GL008",
"SI-CLP",
"SICLP",
"chitinase domain-containing protein 1"
] | [
"REACT:R-HSA-109582",
"REACT:R-HSA-76002",
"REACT:R-HSA-114608"
] | [
"Hemostasis",
"Platelet activation, signaling and aggregation",
"Platelet degranulation"
] | [] | [
[],
[],
[]
] | Complement cascade | Hemostasis | Sialic acid metabolism | Peptide hormone metabolism | 1 |
|
81873-GP1 | GP1 | 81873 | ARPC5L | [
"ARC16-2",
"epididymis secretory sperm binding protein"
] | [
"KEGG:hsa05100",
"KEGG:hsa04144",
"KEGG:hsa05130",
"KEGG:hsa04810",
"KEGG:hsa05132",
"KEGG:hsa05131"
] | [
"Bacterial invasion of epithelial cells",
"Endocytosis",
"Pathogenic Escherichia coli infection",
"Regulation of actin cytoskeleton",
"Salmonella infection",
"Shigellosis"
] | [] | [
[],
[],
[],
[],
[],
[]
] | Activation of SMO | Sphingosine biosynthesis | Bacterial invasion of epithelial cells | Integrin alphaIIb beta3 signaling | 2 |
|
54959-GP1 | GP1 | 54959 | ODAM | [
"odontogenic, ameloblast associated",
"APIN",
"odontogenic ameloblast-associated protein"
] | [
"REACT:R-HSA-977225",
"REACT:R-HSA-392499"
] | [
"Amyloid fiber formation",
"Metabolism of proteins"
] | [] | [
[],
[]
] | Negative regulation of MAPK pathway | Activation of SMO | Degradation of DVL | Amyloid fiber formation | 3 |
|
5770-GP1 | GP1 | 5770 | PTPN1 | [
"PTP1B"
] | [
"KEGG:hsa04520",
"REACT:R-HSA-1280215",
"REACT:R-HSA-982772",
"REACT:R-HSA-109582",
"REACT:R-HSA-168256",
"KEGG:hsa04931",
"KEGG:hsa04910",
"REACT:R-HSA-354192",
"REACT:R-HSA-909733",
"REACT:R-HSA-877300",
"REACT:R-HSA-913531",
"REACT:R-HSA-6807004",
"REACT:R-HSA-76002",
"REACT:R-HSA-76009",
"REACT:R-HSA-8849472",
"REACT:R-HSA-912694",
"REACT:R-HSA-877312",
"REACT:R-HSA-6806834",
"REACT:R-HSA-8848021",
"REACT:R-HSA-162582"
] | [
"Adherens junction",
"Cytokine Signaling in Immune system",
"Growth hormone receptor signaling",
"Hemostasis",
"Immune System",
"Insulin resistance",
"Insulin signaling pathway",
"Integrin alphaIIb beta3 signaling",
"Interferon alpha/beta signaling",
"Interferon gamma signaling",
"Interferon Signaling",
"Negative regulation of MET activity",
"Platelet activation, signaling and aggregation",
"Platelet Aggregation (Plug Formation)",
"PTK6 Down-Regulation",
"Regulation of IFNA signaling",
"Regulation of IFNG signaling",
"Signaling by MET",
"Signaling by PTK6",
"Signal Transduction"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Adherens junction | Glucose metabolism | Glutathione synthesis and recycling | Glutathione metabolism | 0 |
|
2125-GP1 | GP1 | 2125 | EVPL | [
"envoplakin",
"EVPK",
"envoplakin",
"210 kDa cornified envelope precursor protein"
] | [
"REACT:R-HSA-1266738",
"REACT:R-HSA-6809371",
"REACT:R-HSA-6805567"
] | [
"Developmental Biology",
"Formation of the cornified envelope",
"Keratinization"
] | [] | [
[],
[],
[]
] | Pathways in cancer | Central carbon metabolism in cancer | Protein folding | Developmental Biology | 3 |
|
10475-GP1 | GP1 | 10475 | TRIM38 | [
"tripartite motif containing 38",
"RNF15",
"RORET",
"ring finger protein 15",
"tripartite motif-containing protein 38",
"zinc finger protein RoRet"
] | [
"REACT:R-HSA-1280215",
"REACT:R-HSA-168256",
"REACT:R-HSA-877300",
"REACT:R-HSA-913531"
] | [
"Cytokine Signaling in Immune system",
"Immune System",
"Interferon gamma signaling",
"Interferon Signaling"
] | [] | [
[],
[],
[],
[]
] | Oncogene Induced Senescence | Signaling by FGFR2 | Signaling by FGFR3 | Cytokine Signaling in Immune system | 3 |
|
4958-GP1 | GP1 | 4958 | OMD | [
"osteomodulin",
"OSAD",
"SLRR2C",
"osteomodulin",
"KSPG osteomodulin"
] | [
"REACT:R-HSA-3656225",
"REACT:R-HSA-1643685",
"REACT:R-HSA-3781865",
"REACT:R-HSA-1630316",
"REACT:R-HSA-2022854",
"REACT:R-HSA-2022857",
"REACT:R-HSA-1430728",
"REACT:R-HSA-71387"
] | [
"Defective CHST6 causes MCDC1",
"Disease",
"Diseases of glycosylation",
"Glycosaminoglycan metabolism",
"Keratan sulfate biosynthesis",
"Keratan sulfate degradation",
"Metabolism",
"Metabolism of carbohydrates"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[]
] | AURKA Activation by TPX2 | Defective CHST6 causes MCDC1 | Signaling by NOTCH1 in Cancer | Interferon alpha/beta signaling | 1 |
|
1307-GP1 | GP1 | 1307 | COL16A1 | [
"collagen type XVI alpha 1 chain",
"447AA",
"FP1572",
"collagen alpha-1(XVI) chain",
"alpha 1 type XVI collagen",
"collagen, type XVI, alpha 1"
] | [
"REACT:R-HSA-8948216",
"REACT:R-HSA-1442490",
"REACT:R-HSA-1474290",
"REACT:R-HSA-1474228",
"REACT:R-HSA-1474244",
"REACT:R-HSA-216083"
] | [
"Collagen chain trimerization",
"Collagen degradation",
"Collagen formation",
"Degradation of the extracellular matrix",
"Extracellular matrix organization",
"Integrin cell surface interactions"
] | [] | [
[],
[],
[],
[],
[],
[]
] | RIPK1-mediated regulated necrosis | Insulin signaling pathway | Synthesis of DNA | Collagen chain trimerization | 3 |
|
1116-GP1 | GP1 | 1116 | CHI3L1 | [
"chitinase 3 like 1",
"ASRT7",
"CGP-39",
"GP-39",
"GP39",
"HC-gp39",
"HCGP-3P",
"YK-40",
"YKL-40",
"YKL40",
"YYL-40",
"hCGP-39",
"chitinase-3-like protein 1",
"39 kDa synovial protein",
"cartilage glycoprotein 39"
] | [
"REACT:R-HSA-168256",
"REACT:R-HSA-168249",
"REACT:R-HSA-6798695"
] | [
"Immune System",
"Innate Immune System",
"Neutrophil degranulation"
] | [] | [
[],
[],
[]
] | Olfactory Signaling Pathway | T cell receptor signaling pathway | Immune System | Interferon Signaling | 2 |
|
5498-GP1 | GP1 | 5498 | PPOX | [
"protoporphyrinogen oxidase",
"V290M",
"VP",
"protoporphyrinogen oxidase"
] | [
"REACT:R-HSA-189451",
"KEGG:hsa01100",
"REACT:R-HSA-1430728",
"REACT:R-HSA-189445"
] | [
"Heme biosynthesis",
"Metabolic pathways",
"Metabolism",
"Metabolism of porphyrins"
] | [] | [
[],
[],
[],
[]
] | tRNA processing in the nucleus | Heme biosynthesis | Autophagy - other | Phase II conjugation | 1 |
|
23557-GP1 | GP1 | 23557 | SNAPIN | [
"SNAP associated protein",
"BLOC1S7",
"BLOS7",
"BORCS3",
"SNAPAP",
"SNARE-associated protein Snapin",
"BLOC-1 related complex subunit 3",
"BLOC-1 subunit 7",
"SNAP-25-binding protein",
"SNARE associated protein snapin"
] | [
"REACT:R-HSA-432722",
"REACT:R-HSA-199991",
"REACT:R-HSA-5653656"
] | [
"Golgi Associated Vesicle Biogenesis",
"Membrane Trafficking",
"Vesicle-mediated transport"
] | [] | [
[],
[],
[]
] | Interactions of Vpr with host cellular proteins | Golgi Associated Vesicle Biogenesis | Branched-chain amino acid catabolism | Classical antibody-mediated complement activation | 1 |
|
1825-GP1 | GP1 | 1825 | DSC3 | [
"desmocollin 3",
"CDHF3",
"DSC1",
"DSC2",
"DSC4",
"HT-CP",
"desmocollin-3",
"cadherin family member 3",
"desmocollin-4"
] | [
"REACT:R-HSA-1266738",
"REACT:R-HSA-6809371",
"REACT:R-HSA-6805567"
] | [
"Developmental Biology",
"Formation of the cornified envelope",
"Keratinization"
] | [] | [
[],
[],
[]
] | Pathways in cancer | Central carbon metabolism in cancer | Protein folding | Developmental Biology | 3 |
|
407019-GP1 | GP1 | 407019 | MIR27B | [
"microRNA 27b",
"MIRN27B",
"miRNA27B",
"hsa-mir-27b"
] | [
"KEGG:hsa05206"
] | [
"MicroRNAs in cancer"
] | [] | [
[]
] | MicroRNAs in cancer | Vesicle-mediated transport | Cytokine-cytokine receptor interaction | Negative regulation of MAPK pathway | 0 |
|
3615-GP1 | GP1 | 3615 | IMPDH2 | [
"IMPD2",
"IMPDH-II",
"IMP oxireductase 2",
"IMPD 2",
"IMPDH 2",
"epididymis secretory sperm binding protein"
] | [
"KEGG:hsa00983",
"REACT:R-HSA-168256",
"REACT:R-HSA-168249",
"KEGG:hsa01100",
"REACT:R-HSA-1430728",
"REACT:R-HSA-15869",
"REACT:R-HSA-6798695",
"REACT:R-HSA-73847",
"KEGG:hsa00230"
] | [
"Drug metabolism - other enzymes",
"Immune System",
"Innate Immune System",
"Metabolic pathways",
"Metabolism",
"Metabolism of nucleotides",
"Neutrophil degranulation",
"Purine metabolism",
"Purine metabolism"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Mitochondrial biogenesis | Interleukin receptor SHC signaling | Drug metabolism - other enzymes | Glutathione synthesis and recycling | 2 |
|
57823-GP1 | GP1 | 57823 | SLAMF7 | [
"SLAM family member 7",
"19A",
"CD319",
"CRACC",
"CS1",
"SLAM family member 7",
"19A24 protein",
"CD2 subset 1",
"membrane protein FOAP-12",
"protein 19A"
] | [
"REACT:R-HSA-1280218",
"REACT:R-HSA-168256"
] | [
"Adaptive Immune System",
"Immune System"
] | [] | [
[],
[]
] | Generic Transcription Pathway | Cellular Senescence | Olfactory transduction | Adaptive Immune System | 3 |
|
79913-GP1 | GP1 | 79913 | ACTR5 | [
"actin related protein 5",
"Arp5",
"INO80M",
"actin-related protein 5",
"INO80 complex subunit M",
"hARP5"
] | [
"REACT:R-HSA-5688426",
"REACT:R-HSA-73894",
"REACT:R-HSA-392499",
"REACT:R-HSA-5696398",
"REACT:R-HSA-597592",
"REACT:R-HSA-5689603"
] | [
"Deubiquitination",
"DNA Repair",
"Metabolism of proteins",
"Nucleotide Excision Repair",
"Post-translational protein modification",
"UCH proteinases"
] | [] | [
[],
[],
[],
[],
[],
[]
] | Membrane Trafficking | Interferon gamma signaling | Deubiquitination | Heparan sulfate degradation | 2 |
|
693200-GP1 | GP1 | 693200 | MIR615 | [
"microRNA 615",
"MIRN615",
"hsa-mir-615"
] | [
"KEGG:hsa05206"
] | [
"MicroRNAs in cancer"
] | [] | [
[]
] | Vesicle-mediated transport | Cytokine-cytokine receptor interaction | Negative regulation of MAPK pathway | MicroRNAs in cancer | 3 |
|
28957-GP1 | GP1 | 28957 | MRPS28 | [
"mitochondrial ribosomal protein S28",
"COXPD47",
"HSPC007",
"MRP-S35",
"MRPS35",
"28S ribosomal protein S28, mitochondrial",
"28S ribosomal protein S35, mitochondrial",
"S28mt",
"S35mt",
"mitochondrial 28S ribosomal protein S35"
] | [
"REACT:R-HSA-5368287",
"REACT:R-HSA-5389840",
"REACT:R-HSA-5368286",
"REACT:R-HSA-5419276",
"REACT:R-HSA-1852241"
] | [
"Mitochondrial translation",
"Mitochondrial translation elongation",
"Mitochondrial translation initiation",
"Mitochondrial translation termination",
"Organelle biogenesis and maintenance"
] | [] | [
[],
[],
[],
[],
[]
] | Cardiac muscle contraction | RNA polymerase I, eukaryotes | Mitochondrial translation | Respiratory electron transport | 2 |
|
1317-GP1 | GP1 | 1317 | SLC31A1 | [
"solute carrier family 31 member 1",
"COPT1",
"CTR1",
"high affinity copper uptake protein 1",
"copper transport 1 homolog",
"copper transporter 1"
] | [
"REACT:R-HSA-425410",
"KEGG:hsa04978",
"KEGG:hsa01524",
"REACT:R-HSA-425407",
"REACT:R-HSA-382551"
] | [
"Metal ion SLC transporters",
"Mineral absorption",
"Platinum drug resistance",
"SLC-mediated transmembrane transport",
"Transmembrane transport of small molecules"
] | [] | [
[],
[],
[],
[],
[]
] | ESCRT-III complex | ISG15 antiviral mechanism | Metal ion SLC transporters | Amino sugar and nucleotide sugar metabolism | 2 |
|
9322-GP1 | GP1 | 9322 | TRIP10 | [
"thyroid hormone receptor interactor 10",
"CIP4",
"HSTP",
"STOT",
"STP",
"cdc42-interacting protein 4",
"TR-interacting protein 10",
"protein Felic",
"salt tolerant protein",
"salt tolerator",
"thyroid receptor-interacting protein 10"
] | [
"REACT:R-HSA-8856828",
"KEGG:hsa04910",
"REACT:R-HSA-199991",
"REACT:R-HSA-194840",
"REACT:R-HSA-194315",
"REACT:R-HSA-162582",
"REACT:R-HSA-5653656"
] | [
"Clathrin-mediated endocytosis",
"Insulin signaling pathway",
"Membrane Trafficking",
"Rho GTPase cycle",
"Signaling by Rho GTPases",
"Signal Transduction",
"Vesicle-mediated transport"
] | [] | [
[],
[],
[],
[],
[],
[],
[]
] | G-protein mediated events | Regulation of insulin secretion | Clathrin-mediated endocytosis | Signaling by Wnt | 2 |
|
55619-GP1 | GP1 | 55619 | DOCK10 | [
"dedicator of cytokinesis 10",
"DRIP2",
"Nbla10300",
"ZIZ3",
"dopamine receptor interacting protein 2",
"zizimin3"
] | [
"REACT:R-HSA-109582"
] | [
"Hemostasis"
] | [] | [
[]
] | Peptide hormone metabolism | Sialic acid metabolism | Complement cascade | Hemostasis | 3 |
|
1360-GP1 | GP1 | 1360 | CPB1 | [
"carboxypeptidase B1",
"PASP",
"PCPB",
"carboxypeptidase B",
"pancreas-specific protein",
"pancreatic carboxypeptidase B",
"procarboxypeptidase B",
"protaminase",
"tissue carboxypeptidase B"
] | [
"REACT:R-HSA-392499",
"KEGG:hsa04972",
"REACT:R-HSA-2980736",
"KEGG:hsa04974"
] | [
"Metabolism of proteins",
"Pancreatic secretion",
"Peptide hormone metabolism",
"Protein digestion and absorption"
] | [] | [
[],
[],
[],
[]
] | Metabolism of proteins | Effects of PIP2 hydrolysis | Mitochondrial translation initiation | Synthesis of DNA | 0 |
|
57665-GP1 | GP1 | 57665 | RDH14 | [
"retinol dehydrogenase 14",
"PAN2",
"SDR7C4",
"retinol dehydrogenase 14",
"alcohol dehydrogenase PAN2",
"pancreas protein 2"
] | [
"REACT:R-HSA-5365859",
"REACT:R-HSA-5362517",
"REACT:R-HSA-162582"
] | [
"RA biosynthesis pathway",
"Signaling by Retinoic Acid",
"Signal Transduction"
] | [] | [
[],
[],
[]
] | RA biosynthesis pathway | GAB1 signalosome | Complex I biogenesis | ARMS-mediated activation | 0 |
|
55336-GP1 | GP1 | 55336 | FBXL8 | [
"FBL8",
"F-box protein FBL8"
] | [
"REACT:R-HSA-1280218",
"REACT:R-HSA-983169",
"REACT:R-HSA-168256"
] | [
"Adaptive Immune System",
"Class I MHC mediated antigen processing & presentation",
"Immune System"
] | [] | [
[],
[],
[]
] | Cellular Senescence | Olfactory transduction | Adaptive Immune System | Generic Transcription Pathway | 2 |
|
125965-GP1 | GP1 | 125965 | COX6B2 | [
"COXVIB2",
"CT59",
"COX VIb-2",
"cancer/testis antigen 59"
] | [
"KEGG:hsa05010",
"KEGG:hsa04260",
"KEGG:hsa_M00154",
"KEGG:hsa05016",
"KEGG:hsa01100",
"KEGG:hsa00190",
"KEGG:hsa05012"
] | [
"Alzheimer's disease",
"Cardiac muscle contraction",
"Cytochrome c oxidase",
"Huntington's disease",
"Metabolic pathways",
"Oxidative phosphorylation",
"Parkinson's disease"
] | [] | [
[],
[],
[],
[],
[],
[],
[]
] | Prion diseases | Hepatitis B | Hepatitis C | Alzheimer's disease | 3 |
|
63925-GP1 | GP1 | 63925 | ZNF335 | [
"zinc finger protein 335",
"MCPH10",
"NIF-1",
"NIF1",
"NIF2",
"zinc finger protein 335",
"NRC-interacting factor 1"
] | [
"REACT:R-HSA-5619507",
"REACT:R-HSA-1266738"
] | [
"Activation of HOX genes during differentiation",
"Developmental Biology"
] | [] | [
[],
[]
] | RET signaling | Salmonella infection | Activation of HOX genes during differentiation | Sulfur relay system | 2 |
|
79759-GP1 | GP1 | 79759 | ZNF668 | [
"zinc finger protein 668",
"zinc finger protein 668"
] | [
"REACT:R-HSA-74160",
"REACT:R-HSA-212436"
] | [
"Gene Expression",
"Generic Transcription Pathway"
] | [] | [
[],
[]
] | Pre-NOTCH Expression and Processing | Gene Expression | Protein methylation | Viral Messenger RNA Synthesis | 1 |
|
1827-GP1 | GP1 | 1827 | RCAN1 | [
"regulator of calcineurin 1",
"ADAPT78",
"CSP1",
"DSC1",
"DSCR1",
"MCIP1",
"RCN1",
"calcipressin-1",
"Down syndrome candidate region 1",
"Down syndrome critical region gene 1",
"near DSCR proline-rich protein"
] | [
"KEGG:hsa04921",
"KEGG:hsa04919"
] | [
"Oxytocin signaling pathway",
"Thyroid hormone signaling pathway"
] | [] | [
[],
[]
] | Oxytocin signaling pathway | Cargo concentration in the ER | Cellular response to hypoxia | RAB geranylgeranylation | 0 |
|
693222-GP1 | GP1 | 693222 | MIR637 | [
"microRNA 637",
"MIRN637",
"hsa-mir-637"
] | [
"REACT:R-HSA-109581",
"REACT:R-HSA-5357801"
] | [
"Apoptosis",
"Programmed Cell Death"
] | [] | [
[],
[]
] | RET signaling | Apoptosis | EGFR downregulation | eNOS activation | 1 |
|
8487-GP1 | GP1 | 8487 | GEMIN2 | [
"gem nuclear organelle associated protein 2",
"SIP1",
"SIP1-delta",
"gem-associated protein 2",
"SMN interacting protein 1-delta",
"component of gems 2",
"survival of motor neuron protein interacting protein 1"
] | [
"REACT:R-HSA-74160",
"REACT:R-HSA-194441",
"KEGG:hsa03013",
"REACT:R-HSA-191859",
"KEGG:hsa_M00426"
] | [
"Gene Expression",
"Metabolism of non-coding RNA",
"RNA transport",
"snRNP Assembly",
"Survival motor neuron (SMN) complex"
] | [] | [
[],
[],
[],
[],
[]
] | Viral Messenger RNA Synthesis | Gene Expression | Pre-NOTCH Expression and Processing | Protein methylation | 1 |
|
54848-GP1 | GP1 | 54848 | ARHGEF38 | [] | [
"REACT:R-HSA-416482",
"REACT:R-HSA-388396",
"REACT:R-HSA-193648",
"REACT:R-HSA-193704",
"REACT:R-HSA-194840",
"REACT:R-HSA-372790",
"REACT:R-HSA-194315",
"REACT:R-HSA-166520",
"REACT:R-HSA-162582"
] | [
"G alpha (12/13) signalling events",
"GPCR downstream signaling",
"NRAGE signals death through JNK",
"p75 NTR receptor-mediated signalling",
"Rho GTPase cycle",
"Signaling by GPCR",
"Signaling by Rho GTPases",
"Signalling by NGF",
"Signal Transduction"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Chylomicron-mediated lipid transport | Signaling by BMP | Signaling by Insulin receptor | G alpha (12/13) signalling events | 3 |
|
257062-GP1 | GP1 | 257062 | CATSPERD | [
"cation channel sperm associated auxiliary subunit delta",
"TMEM146",
"cation channel sperm-associated protein subunit delta",
"catSper-delta",
"catSperdelta",
"catsper channel auxiliary subunit delta",
"transmembrane protein 146"
] | [
"REACT:R-HSA-1187000",
"REACT:R-HSA-1474165",
"REACT:R-HSA-1300642"
] | [
"Fertilization",
"Reproduction",
"Sperm Motility And Taxes"
] | [] | [
[],
[],
[]
] | FCGR activation | rRNA processing | Glucose transport | Fertilization | 3 |
|
1021-GP1 | GP1 | 1021 | CDK6 | [
"cyclin dependent kinase 6",
"MCPH12",
"PLSTIRE",
"cyclin-dependent kinase 6",
"cell division protein kinase 6"
] | [
"KEGG:hsa05224",
"REACT:R-HSA-1640170",
"KEGG:hsa04110",
"KEGG:hsa_M00692",
"REACT:R-HSA-69278",
"REACT:R-HSA-2262752",
"REACT:R-HSA-2559583",
"KEGG:hsa05220",
"REACT:R-HSA-69231",
"REACT:R-HSA-69236",
"KEGG:hsa05214",
"KEGG:hsa05161",
"KEGG:hsa05162",
"KEGG:hsa05218",
"KEGG:hsa05206",
"KEGG:hsa05223",
"REACT:R-HSA-2559585",
"KEGG:hsa04115",
"KEGG:hsa05212",
"KEGG:hsa05200",
"KEGG:hsa04151",
"KEGG:hsa05222",
"KEGG:hsa05203"
] | [
"Breast cancer",
"Cell Cycle",
"Cell cycle",
"Cell cycle - G1/S transition",
"Cell Cycle, Mitotic",
"Cellular responses to stress",
"Cellular Senescence",
"Chronic myeloid leukemia",
"Cyclin D associated events in G1",
"G1 Phase",
"Glioma",
"Hepatitis B",
"Measles",
"Melanoma",
"MicroRNAs in cancer",
"Non-small cell lung cancer",
"Oncogene Induced Senescence",
"p53 signaling pathway",
"Pancreatic cancer",
"Pathways in cancer",
"PI3K-Akt signaling pathway",
"Small cell lung cancer",
"Viral carcinogenesis"
] | [] | [
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[],
[]
] | Thyroid hormone synthesis | Breast cancer | Thiamine metabolism | Diseases of metabolism | 1 |
|
4308-GP1 | GP1 | 4308 | TRPM1 | [
"CSNB1C",
"LTRPC1",
"MLSN1",
"long transient receptor potential channel 1",
"melastatin-1",
"transient receptor potential melastatin family"
] | [
"REACT:R-HSA-983712",
"REACT:R-HSA-2672351",
"REACT:R-HSA-382551",
"REACT:R-HSA-3295583"
] | [
"Ion channel transport",
"Stimuli-sensing channels",
"Transmembrane transport of small molecules",
"TRP channels"
] | [] | [
[],
[],
[],
[]
] | Ion channel transport | Metabolism of nitric oxide | Semaphorin interactions | Terminal pathway of complement | 0 |
|
10772-GP1 | GP1 | 10772 | SRSF10 | [
"FUSIP1",
"FUSIP2",
"NSSR",
"PPP1R149",
"SFRS13",
"SFRS13A",
"SRp38",
"SRrp40",
"TASR",
"TASR1",
"TASR2",
"40 kDa SR-repressor protein",
"SR splicing factor 10",
"TLS-associated SR protein",
"TLS-associated protein TASR",
"TLS-associated protein with SR repeats",
"neural-salient SR protein",
"protein phosphatase 1, regulatory subunit 149",
"splicing factor SRp38"
] | [
"REACT:R-HSA-74160",
"REACT:R-HSA-72172",
"REACT:R-HSA-72163",
"KEGG:hsa03040"
] | [
"Gene Expression",
"mRNA Splicing",
"mRNA Splicing - Major Pathway",
"Spliceosome"
] | [] | [
[],
[],
[],
[]
] | Protein methylation | Gene Expression | Viral Messenger RNA Synthesis | Pre-NOTCH Expression and Processing | 1 |