diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8.srt
new file mode 100644
index 0000000000000000000000000000000000000000..888eacc1380e7dad893d30fa602fbd1b8708df08
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8.srt
@@ -0,0 +1,1437 @@
+1
+00:00:05,150 --> 00:00:07,690
+بسم الله الرحمن الرحيم محاضرتنا اليوم عن ال
+
+2
+00:00:07,690 --> 00:00:10,670
+nervous system ومكونات الـ nervous system  ونشوف
+
+3
+00:00:10,670 --> 00:00:15,970
+الخلية المكونة للـ nervous system وتقسيماته طبعا
+
+4
+00:00:15,970 --> 00:00:19,410
+أحنا معروف أن الـ nervous system هو والـ endocrine
+
+5
+00:00:19,410 --> 00:00:23,980
+system هما اللذان ينظمان عملية... في وظائف الجسم
+
+6
+00:00:23,980 --> 00:00:28,240
+كلها، ونعرف أن الجسم أول ما يتعرض لأي insult أو
+
+7
+00:00:28,240 --> 00:00:32,740
+يتعرض لخوف أو يتعرض لأذى يكون أسرع شيء في
+
+8
+00:00:32,740 --> 00:00:35,600
+التصرف هو الـ nervous system وليه طبعا الـ
+
+9
+00:00:35,600 --> 00:00:38,540
+endocrine system  الذي يحافظ على
+
+10
+00:00:38,540 --> 00:00:43,900
+hemostasis تبع الجسم، يبقى هنتعرف على مكونات الـ
+
+11
+00:00:43,900 --> 00:00:47,150
+nervous system، هو فيه عندنا نوعان من الـ nervous
+
+12
+00:00:47,150 --> 00:00:49,430
+system، فيه عندنا الـ central nervous system وعندنا
+
+13
+00:00:49,430 --> 00:00:53,790
+الـ peripheral nervous system، الـ central nervous
+
+14
+00:00:53,790 --> 00:00:56,670
+system هو عبارة عن الـ brain and spinal cord، والـ
+
+15
+00:00:56,670 --> 00:00:59,590
+peripheral nervous system هو عبارة عن الأعصاب
+
+16
+00:00:59,590 --> 00:01:03,930
+التي تخرج من الـ spinal cord أو من الـ brain إلى
+
+17
+00:01:03,930 --> 00:01:09,200
+أجزاء الجسم كلها. طبعا إيش الـ function؟ أحنا بنعرف
+
+18
+00:01:09,200 --> 00:01:13,000
+أنه في الـ central nervous system بيكون فيه عندي
+
+19
+00:01:13,000 --> 00:01:16,940
+ثلاث وظائف، أول حاجة الـ sensory وفيه...
+
+20
+00:01:16,940 --> 00:01:20,360
+ثلاث وظائف، آسف، الـ sensory function والـ
+
+21
+00:01:20,360 --> 00:01:23,600
+motor function والـ integration function، طبعا كتير
+
+22
+00:01:23,600 --> 00:01:27,500
+مهم الـ link بين هذول الثلاث functions، لأنه إذا
+
+23
+00:01:27,500 --> 00:01:31,320
+كنا بنحس ما بنقدرش نتصرف، فطبعا بيصير فيه عندنا مشكلة
+
+24
+00:01:31,320 --> 00:01:35,020
+وإذا ما فيش عندنا إحساس فهذه مشكلة طبعا أكبر لأن
+
+25
+00:01:35,020 --> 00:01:38,900
+ممكن واحد يتعرض لمخاطر، هلأ إذا أنا حاسة إن أنا
+
+26
+00:01:38,900 --> 00:01:42,700
+حطيت إيدي على شيء ساخن وهذا، وحاسة إن السخن أنا مش
+
+27
+00:01:42,700 --> 00:01:46,520
+قادرة أرفع إيدي عنها فهذه هتؤدي إلى الحرق، تمام؟
+
+28
+00:01:46,520 --> 00:01:51,360
+لكن كمان لو أنا عندي حركة كويسة لكن ما فيش
+
+29
+00:01:51,360 --> 00:01:54,320
+عندي إحساس، فأنا إيدي موجودة على شيء ساخن على
+
+30
+00:01:54,320 --> 00:01:57,560
+دفاية أو على بوتاجاز أو على قدر، فأنا هأحرقه مش
+
+31
+00:01:57,560 --> 00:02:02,300
+هتوصل الإشارة للدماغ تقول لي إن فيه عندي مشكلة
+
+32
+00:02:02,300 --> 00:02:07,020
+فهتؤدي لحرق، الـ integration فأنا ممكن أحط إيدي على
+
+33
+00:02:07,020 --> 00:02:10,600
+شيء ساخن لكن ما يوصل التفسير هذا للدماغ اللي على
+
+34
+00:02:10,600 --> 00:02:15,250
+أساسه هيصير التصرف بعد هيك، يقوله ارفعي يدك عن الـ
+
+35
+00:02:15,250 --> 00:02:20,030
+...ال...الدفاية أو عن ال... شيء الساخن، فيبقى هذول
+
+36
+00:02:20,030 --> 00:02:23,070
+الثلاث components لازم تكون عندي عشان آخذ good
+
+37
+00:02:23,070 --> 00:02:25,790
+function، لازم يكون عندي الـ sensory والـ motor والـ
+
+38
+00:02:25,790 --> 00:02:29,530
+integrative function intact، إيش هي الـ sensory؟
+
+39
+00:02:29,530 --> 00:02:32,330
+فهي عبارة عن sensory receptors gathering
+
+40
+00:02:32,330 --> 00:02:36,670
+information، الـ information هذه بتروح وين؟ أنا
+
+41
+00:02:36,670 --> 00:02:40,230
+بأخذ، طبعا فيه عندي الـ special senses مثلًا زي
+
+42
+00:02:40,230 --> 00:02:43,590
+البصر، أنا ماشية في الطريق، فيه قدامي حفرة، فيه
+
+43
+00:02:43,590 --> 00:02:47,170
+قدامي درج، فأنا بيعطيني order، بوصل ل... بروح
+
+44
+00:02:47,170 --> 00:02:50,150
+للدماغ، أول شيء الإشارة بتروح للدماغ، بتقول إن فيه
+
+45
+00:02:50,150 --> 00:02:54,030
+هنا عَطبَة، خلّي بالك لما تنزلي، أحسنتِ توقّعِه، فبيعطيني
+
+46
+00:02:54,030 --> 00:02:57,890
+إشارة، أول شيء بتروح إشارة عندك بتعمل
+
+47
+00:02:57,890 --> 00:03:00,810
+interpretation، بتعمل interpretation بتقول له هنا فيه
+
+48
+00:03:00,810 --> 00:03:04,290
+عَطبَة، هنا فيه حفرة، ابعدي عنها، فبيجي الـ order لـ
+
+49
+00:03:04,290 --> 00:03:07,830
+skeletal system عشان هو يتصرّف، فيبقى sensory
+
+50
+00:03:07,830 --> 00:03:11,190
+receptors gathering information، بتاخد الـ
+
+51
+00:03:11,190 --> 00:03:16,850
+information من البيئة المحيطة، بترسلها لمين؟ للـ
+
+52
+00:03:16,850 --> 00:03:20,990
+central nervous system أو للـ brain، في بعض الحركات
+
+53
+00:03:20,990 --> 00:03:23,970
+بتكون reflex يعني ما بتوصل للـ brain، يعني أنا لو حطيت
+
+54
+00:03:23,970 --> 00:03:26,650
+إيدي على مسكة فاتحة الـ microwave، بدي آخذ الصحن
+
+55
+00:03:26,650 --> 00:03:30,450
+لقيته ساخن، برميه، لأنه ما وصلش الـ brain، هذه reflex على طول
+
+56
+00:03:30,450 --> 00:03:34,730
+أنا حسيت أنه ساخن، automatic رميته وحاميت نفسي، فهذه
+
+57
+00:03:34,730 --> 00:03:38,090
+في بعض الإشارات، دعست على الدبوس، دعست على الدبوس
+
+58
+00:03:38,090 --> 00:03:42,830
+هذا لسه قبل ما توصل الإشارة للـ brain، منكون الدبوس خرق
+
+59
+00:03:42,830 --> 00:03:46,250
+رجلنا، لأ هو على طول فورًا أنت بتروح ترفع، إحنا بنقول
+
+60
+00:03:46,250 --> 00:03:51,110
+بنرفع رجلنا عن الدبوس، هذه في حالة reflex أما الـ integration فهي الـ sensor والـ
+
+61
+00:03:51,110 --> 00:03:53,810
+information used to create الـ sensation وكمان الـ
+
+62
+00:03:53,810 --> 00:03:57,310
+memory والـ thoughts والـ decisions، فهذه كلها أمور
+
+63
+00:03:57,310 --> 00:04:01,110
+بتحتاج لـ interpretation أو ترجمة، فهي integrated
+
+64
+00:04:01,110 --> 00:04:07,990
+function، أما الـ motor function فبتكلم عن الـ action
+
+65
+00:04:07,990 --> 00:04:14,590
+أنا بدي أبعد هنا لأنه فيه هنا حفرة، أنا بدي أرفع
+
+66
+00:04:14,590 --> 00:04:18,730
+إيدي لأنه هذا الشيء ساخن، أنا والله بشوف إنّه
+
+67
+00:04:18,730 --> 00:04:22,070
+والله فيه سيارة جاية بتقطع الشارع، تمام؟ فهذه عبارة عن
+
+68
+00:04:28,010 --> 00:04:31,970
+عملية الـ integration ما بين الـ sensory وما بين الـ
+
+69
+00:04:31,970 --> 00:04:37,070
+...الـ motor، وبعدين هي اللي بتعطينا التفسير لظواهر
+
+70
+00:04:37,070 --> 00:04:41,230
+اللي حولنا، أما الـ motor، لأ الـ motor فهي بتعطيني
+
+71
+00:04:41,230 --> 00:04:45,410
+effort، بتحرك السير على طول، أنا الـ impulse هذه
+
+72
+00:04:45,410 --> 00:04:50,170
+بتقول ارفعي يدك، إميلِ على اليمين، إميلِ على اليسار، ابعدي،
+
+73
+00:04:50,170 --> 00:04:54,430
+اقفي، طبعا الـ organization of the nervous system
+
+74
+00:04:54,430 --> 00:04:59,150
+... الـ organized to detect the changes in
+
+75
+00:04:59,150 --> 00:05:02,630
+the internal and external environment، يعني الـ
+
+76
+00:05:02,630 --> 00:05:06,550
+nervous system ما بس بتنظر، بيعطيني مؤشرات على
+
+77
+00:05:06,550 --> 00:05:10,430
+البيئة اللي حواليّا أو إشارات لأ كمان internally
+
+78
+00:05:10,430 --> 00:05:13,910
+إيش بيصير، ولأ أنا حاسس حالي ساخن، أنا حاسس حالي
+
+79
+00:05:13,910 --> 00:05:17,930
+بارد، أنا حاسس حالي جعان، أنا حاسس حالي عطشان
+
+80
+00:05:17,930 --> 00:05:22,490
+كمان، and initiate appropriate response، طيب أنا
+
+81
+00:05:22,490 --> 00:05:26,470
+جعان، بفضل أروح آكل، أنا عشان بدي أروح أشرب، أنا والله
+
+82
+00:05:26,470 --> 00:05:30,890
+حاسس حالي حرّ، بدي أروح أفتح نافذة أو بدي
+
+83
+00:05:30,890 --> 00:05:35,990
+أغيّر ملابسي أو بدي آخذ دش أو whatever، طبعا الـ sub
+
+84
+00:05:35,990 --> 00:05:40,050
+divisions للـ system، فيه عندنا الـ central nervous
+
+85
+00:05:40,050 --> 00:05:43,150
+system أو فيه عندنا الـ peripheral nervous system، الـ
+
+86
+00:05:43,150 --> 00:05:45,630
+central nervous system عبارة عن الـ brain and
+
+87
+00:05:45,630 --> 00:05:52,150
+spinal cord، طبعا هو إيش وظيفته؟ integrates sensory
+
+88
+00:05:52,150 --> 00:05:55,650
+information، evaluate it وكمان بيعطينا الـ response
+
+89
+00:05:55,650 --> 00:06:01,570
+أو outgoing response، بالضبط زي ما أنا قلت من الأول
+
+90
+00:06:01,570 --> 00:06:05,230
+أنا حسيت هنا هذا شيء ساخن، راح للدماغ اللي والله هنا
+
+91
+00:06:05,230 --> 00:06:08,690
+فيه حاجة سخنة، ابعدي عنها، فبيجيني الـ order إني أنا
+
+92
+00:06:08,690 --> 00:06:12,430
+أشيل إيدي عنها، طبعا أما الـ peripheral nervous
+
+93
+00:06:12,430 --> 00:06:15,890
+system فهو بيستقبل من الـ brain وبيستقبل من الـ
+
+94
+00:06:15,890 --> 00:06:19,870
+spinal cord، الـ cranial nerve بتأخذ الأمر لأنها هي
+
+95
+00:06:19,870 --> 00:06:23,950
+في منطقتها قبل الـ spinal cord، فبتطلع من الـ cranial
+
+96
+00:06:23,950 --> 00:06:27,990
+نفسها، فبتسمى...بتأخذ من الـ brain للـ periphery، ها
+
+97
+00:06:27,990 --> 00:06:32,350
+دي بتغذي عضلات الوجه والـ swallowing والـ neck
+
+98
+00:06:32,350 --> 00:06:35,830
+accessory، إيه مثلًا؟ أما الـ spinal nerve فهي بتطلع
+
+99
+00:06:35,830 --> 00:06:38,510
+من الـ spinal cord، بتروح للـ appendicular
+
+100
+00:06:38,510 --> 00:06:41,970
+musculoskeletal system على أساس أنه تعمل، ليه تعمل
+
+101
+00:06:41,970 --> 00:06:48,410
+perform للحركة وكمان على الـ internal organs، هانبدأ
+
+102
+00:06:48,410 --> 00:06:54,130
+بالصور الموضحة بالأشكال، فعنا الصورة هذه بتوضح
+
+103
+00:06:54,130 --> 00:06:58,610
+أنه فيه عندنا هنا الـ brain والـ spinal cord، هذول
+
+104
+00:06:58,610 --> 00:07:01,570
+الـ central nervous system، وفيه إنّه الـ cranial
+
+105
+00:07:01,570 --> 00:07:08,570
+nerve والـ spinal nerve اللي هي بتغذي الـ periphery
+
+106
+00:07:08,570 --> 00:07:11,450
+of the body
+
+107
+00:07:13,130 --> 00:07:18,170
+طبعا فيه هنا sensory divisions للـ peripheral nervous،
+
+108
+00:07:18,170 --> 00:07:21,250
+هنا sensory وفيه عندنا motor وكمان الـ motor
+
+109
+00:07:21,250 --> 00:07:27,850
+بتنقسم لـ somatic and autonomic nervous system، الـ
+
+110
+00:07:27,850 --> 00:07:31,370
+sensory طبعا بتأخذ الـ pick up sensory information
+
+111
+00:07:31,370 --> 00:07:36,190
+and deliver it to the central nervous system،
+
+112
+00:07:36,190 --> 00:07:42,550
+بتأخذ المعلومة أو الإشارة عن طريق الجسم وبترسلها للـ
+
+113
+00:07:42,550 --> 00:07:45,930
+central nervous system سواء للـ spinal cord اللي
+
+114
+00:07:45,930 --> 00:07:50,390
+بيرفعها عن طريق الـ elevators تبعته إلى الدماغ، فيه
+
+115
+00:07:50,390 --> 00:07:54,370
+أن الـ motor divisions بتعطيني information عن الـ
+
+116
+00:07:54,370 --> 00:07:59,670
+muscles and glands، يعني بتعطيني حالة العضلات وحالة
+
+117
+00:07:59,670 --> 00:08:05,280
+الغدد اللي موجودة في الجسم، الـ motor system اللي
+
+118
+00:08:05,280 --> 00:08:08,240
+بينقسم لـ somatic و autonomous، الـ somatic هو اللي
+
+119
+00:08:08,240 --> 00:08:12,700
+بيروح للعضلات، الـ muscles system اللي بيعمل لي الحركة، يعني هو
+
+120
+00:08:12,700 --> 00:08:17,440
+اللي بيقول لي ابعدي، روحي، تعالي، أمسكي، اشربي، أمسكي
+
+121
+00:08:17,440 --> 00:08:21,420
+الكباية، العضلات هي اللي بتعمل هذا الشغل، أما الـ
+
+122
+00:08:21,420 --> 00:08:25,640
+autonomous فهوكمان اللي هو الجهاز اللاإرادي، بمعنى
+
+123
+00:08:25,640 --> 00:08:29,020
+أنه أنا ما بتحكم في عضلة القلب، أقول لها دقي وما
+
+124
+00:08:29,020 --> 00:08:32,000
+تدقيش، تمام؟ الـ glands أنا ما بتحكم بالإفرازات
+
+125
+00:08:32,000 --> 00:08:38,600
+تبعها، لكن فيه nervous system بيتحكم فعلًا فيها،
+
+126
+00:08:38,600 --> 00:08:41,580
+carries information to the smooth muscle والـ
+
+127
+00:08:41,580 --> 00:08:46,120
+cardiac muscle and the glands، طبعا هذا الرسم
+
+128
+00:08:46,120 --> 00:08:50,220
+التوضيحي بيوضح لنا حالة الأعصاب
+
+129
+00:08:53,990 --> 00:09:00,310
+إحنا وين وصلنا؟ هنا، عندنا الـ brain زي ما إحنا
+
+130
+00:09:00,310 --> 00:09:05,090
+شايفين، والـ spinal cord، مثل ما عملنا الـ spinal nerve،
+
+131
+00:09:05,090 --> 00:09:08,510
+طبعًا فيه عندنا الـ sensory receptors هي اللي بترفع
+
+132
+00:09:08,510 --> 00:09:12,170
+للـ brain، فيه عندنا الـ motor اللي هي الـ somatic
+
+133
+00:09:12,170 --> 00:09:14,830
+اللي بتروح على الـ skeletal muscle وفيه عندنا الـ
+
+134
+00:09:14,830 --> 00:09:18,290
+autonomic اللي بتروح على الـ smooth والـ cardiac and
+
+135
+00:09:18,290 --> 00:09:24,300
+glands، الـ... الـ systems according to the type of
+
+136
+00:09:24,300 --> 00:09:28,160
+organs they innervate، فيه عندنا الـ somatic الـ
+
+137
+00:09:28,160 --> 00:09:30,920
+somatic motor وفيه somatic sensory، طبيعي إنه
+
+138
+00:09:30,920 --> 00:09:35,480
+الجسدية أو خلال الأعصاب الجسدية، الـ somatic motor
+
+139
+00:09:35,480 --> 00:09:38,560
+division carries information to the somatic
+
+140
+00:09:38,560 --> 00:09:42,380
+effectors اللي هي الـ skeletal مثلًا، أما الـ sensory
+
+141
+00:09:42,380 --> 00:09:46,780
+divisions فهي carry feedback، بتأخذ الـ feedback من
+
+142
+00:09:46,780 --> 00:09:52,740
+العضلات to the somatic integration
+
+143
+00:09:52,740 --> 00:09:56,560
+center of the central nervous، يعني الـ motor هي اللي
+
+144
+00:09:56,560 --> 00:10:02,300
+بترسل، والـ sensor هي اللي بتستقبل، هذا باختصار، أما
+
+145
+00:10:02,300 --> 00:10:06,200
+الـ autonomic nervous system عبارة عن efferent
+
+146
+00:10:06,200 --> 00:10:09,810
+divisions، الـ different divisions هذه فيها الـ
+
+147
+00:10:09,810 --> 00:10:13,150
+sympathetic والـ parasympathetic، وظيفتها carry
+
+148
+00:10:13,150 --> 00:10:15,670
+information to the autonomic and visceral
+
+149
+00:10:15,670 --> 00:10:19,270
+effectors اللي هي smooth and cardiac muscle and
+
+150
+00:10:19,270 --> 00:10:23,350
+glands، هاي الـ sympathetic divisions عبارة عن اللي
+
+151
+00:10:23,350 --> 00:10:29,160
+هو الـ... يعني فلّان نقول، وسيلة الدفاع عن الجسم، عادة
+
+152
+00:10:29,160 --> 00:10:32,760
+بتعمل preparation to the body to deal with any
+
+153
+00:10:32,760 --> 00:10:37,500
+threat to the internal environment، يعني إذا
+
+154
+00:10:37,500 --> 00:10:40,860
+كان أي شيء بيشكّل خطر، فعلى طول الـ sympathetic
+
+155
+00:10:40,860 --> 00:10:48,100
+system هو بيشتغل حتى تتمكن من الهروب من الخطر، عادة
+
+156
+00:10:48,620 --> 00:10:51,220
+أما الـ parasympathetic system فهذا بيشتغل في الـ
+
+157
+00:10:51,220 --> 00:10:55,000
+rest، هذا هو الراحة، هو مرتاح الشخص، قاعد نايم، اللي
+
+158
+00:10:55,000 --> 00:10:57,820
+بيشتغل، coordinate the body's normal resting
+
+159
+00:10:57,820 --> 00:11:01,580
+activity، الـ visceral sensory divisions carry في
+
+160
+00:11:01,580 --> 00:11:04,440
+كتاب feedback information للـ autonomic
+
+161
+00:11:04,440 --> 00:11:08,840
+integrating center of the... يعني هنا فيه عندي في
+
+162
+00:11:08,840 --> 00:11:14,900
+كل الفذرة أو الـ internal organs فيها sensory، الـ
+
+163
+00:11:14,900 --> 00:11:19,180
+sensory neurons هذه بترفع ليه؟ على الـ autonomic
+
+164
+00:11:19,180 --> 00:11:22,620
+nervous system، من الـ autonomic nervous system للـ
+
+165
+00:11:22,620 --> 00:11:27,700
+brain أو للـ central nervous system، تكلمنا عن الـ
+
+166
+00:11:27,700 --> 00:11:30,940
+afferent and efferent divisions، الـ afferent هي
+
+167
+00:11:30,940 --> 00:11:35,240
+اللي بترفع، هي عبارة عن incoming sensory pathways، هي
+
+168
+00:11:35,240 --> 00:11:38,880
+اللي بترفع الـ ways... هي بترفع للدماغ، أما الـ
+
+169
+00:11:38,880 --> 00:11:41,460
+efferent فهي اللي بتعطينا العودة، يعني إحنا في
+
+170
+00:11:41,460 --> 00:11:45,420
+عندنا elevator طالع وفيه عندنا elevator نازل، الـ
+
+171
+00:11:45,420 --> 00:11:50,180
+afferent هي المصعد اللي طالع للـ brain أما الـ
+
+172
+00:11:50,180 --> 00:11:54,080
+efferent هي المصعد اللي نازل من الـ brain للـ
+
+173
+00:11:54,080 --> 00:11:55,120
+motor pathways
+
+174
+00:11:58,750 --> 00:12:04,470
+طبعا الـ components of somatic sensory، عادة الـ
+
+175
+00:12:04,470 --> 00:12:07,950
+general somatic senses زي الـ touch، الـ pain، الـ
+
+176
+00:12:07,950 --> 00:12:11,010
+pressure، الـ vibration، الـ temperature، الـ
+
+177
+00:12:11,010 --> 00:12:13,970
+proprioception اللي موجود في...اللي بيعطيني حالة
+
+178
+00:12:13,970
+
+223
+00:15:03,030 --> 00:15:07,170
+هي excitable وهي اللي بتعمل transmission  للـ impulse
+
+224
+00:15:07,170 --> 00:15:10,590
+اللي بتساعد على حركة الـ impulse يعني هي الكهرباء
+
+225
+00:15:10,790 --> 00:15:15,510
+خلّيني أقول هي السلك الكهربائي اللي بيوصل الكهرباء
+
+226
+00:15:15,510 --> 00:15:18,230
+من الـ central nervous system للـ peripheral
+
+227
+00:15:18,230 --> 00:15:21,710
+nervous system، والعزيزي أما الـ glial cell فهي non-
+
+228
+00:15:21,710 --> 00:15:25,690
+excitable يعني ممنوع بتعطيني إشارات كهربائية، لكن
+
+229
+00:15:25,690 --> 00:15:29,610
+بتعطيني support و protection، زي وظيفة اللي هي الـ
+
+230
+00:15:29,610 --> 00:15:32,850
+connective tissue، بس لأن الـ nervous system بيحتوي
+
+231
+00:15:32,850 --> 00:15:36,690
+على connective tissue فهو بيحتوي على glial cells
+
+232
+00:15:36,690 --> 00:15:40,400
+اللي بتعطيني support و protection. طب إيش ترتيبة
+
+233
+00:15:40,400 --> 00:15:43,700
+النيرون؟ أي نيرون موجود في عيننا، الـ Structural
+
+234
+00:15:43,700 --> 00:15:46,520
+unit هو التعريف هو الـ Structural and Functional
+
+235
+00:15:46,520 --> 00:15:51,280
+Unit للنرفس سيستم، هو بيتكون من نيرون و two processes
+
+236
+00:15:51,280 --> 00:15:57,040
+الـ process الأول اللي هو الـ Dendrites اللي هو
+
+237
+00:15:57,040 --> 00:16:03,020
+بيستقبل الإشارة، والـ Axon اللي هو بيرسل الإشارة
+
+238
+00:16:03,020 --> 00:16:05,180
+طيب
+
+239
+00:16:06,110 --> 00:16:12,070
+إيش الـ characteristics بتاعة الـ neuron؟ هو highly
+
+240
+00:16:12,070 --> 00:16:18,590
+metabolic rates يعني الـ metabolism عنده عالي، لكن هو
+
+241
+00:16:18,590 --> 00:16:23,530
+extreme longevity بيعيش فترات طويلة، وكمان non-
+
+242
+00:16:23,530 --> 00:16:28,660
+mitotic يعني ما بيصير فيه انقسامات للـ neuron، يعني
+
+243
+00:16:28,660 --> 00:16:30,740
+إحنا بنعرف إن الخلية بيصير فيها انقسام، الـ neurons
+
+244
+00:16:30,740 --> 00:16:34,440
+لا ما بيصير فيها انقسام، أه؟ طيب الـ neuron comes
+
+245
+00:16:34,440 --> 00:16:40,040
+in all shapes and sizes and share certain basic
+
+246
+00:16:40,040 --> 00:16:43,320
+structural features اللي هي الـ cell body والـ axon
+
+247
+00:16:43,320 --> 00:16:47,020
+and dendritic. وهنا زي ما إحنا شايفين، الـ cell body
+
+248
+00:16:47,020 --> 00:16:50,780
+أي cell body فيها أو بيسموها الـ soma فيها الـ
+
+249
+00:16:50,780 --> 00:16:55,260
+nucleus. الـ Dendrites هي التشعبات اللي إحنا
+
+250
+00:16:55,260 --> 00:17:00,600
+شايفينها هنا، ثم الـ Axon فهي الـ طويلة اللي قدام
+
+251
+00:17:00,600 --> 00:17:05,520
+هنشوفها، الـ process الطويلة
+
+252
+00:17:05,520 --> 00:17:14,040
+دي هي الـ center للـ neuron، control center طبعاً
+
+253
+00:17:14,040 --> 00:17:19,720
+responsible for تستقبل receiving، integrating and
+
+254
+00:17:19,720 --> 00:17:25,910
+sending nerve impulses. أما تركيبها فهي عبارة عن
+
+255
+00:17:25,910 --> 00:17:31,270
+plasma membrane وفيها cytoplasm، طبعاً أي خلية فيها
+
+256
+00:17:31,270 --> 00:17:35,890
+plasma membrane و cytoplasm، فيها nucleus with
+
+257
+00:17:35,890 --> 00:17:41,190
+a prominent nucleus. في عندنا الـ chromatophilic
+
+258
+00:17:41,190 --> 00:17:47,110
+substances وفي عندنا many ribosomes. تركيب أي خلية
+
+259
+00:17:47,110 --> 00:17:50,030
+أما الـ axons فهو عبارة عن
+
+260
+00:17:53,030 --> 00:17:57,310
+إيش؟ بتكون من single process extending from the
+
+261
+00:17:57,310 --> 00:18:06,850
+axon hillock، بيبدا بيطلع من الـ cell body، بتكون
+
+262
+00:18:06,850 --> 00:18:11,670
+زي العنق له، sometimes covered by a fatty layer اسمه
+
+263
+00:18:11,670 --> 00:18:15,570
+الميالين شيث، ووظيفته to conduct nerve impulses
+
+264
+00:18:15,570 --> 00:18:21,240
+away from the cell body of the neuron. وهذا شكل الـ axon
+
+265
+00:18:21,240 --> 00:18:26,380
+هو long process زي ما إحنا شايفينه، وهنا إحنا زي ما
+
+266
+00:18:26,380 --> 00:18:31,840
+إحنا شايفينها، الـ axon hillock اللي هي بداية الـ axon
+
+267
+00:18:31,840 --> 00:18:37,060
+وبعدين في عندنا الشيفر وفي عندنا الـ nodes of
+
+268
+00:18:37,060 --> 00:18:41,160
+Ranvier. وظيفته
+
+269
+00:18:41,160 --> 00:18:46,570
+أنه يرسل  send the impulse. أما الـ Dendrites فهو المستقبل،
+
+270
+00:18:46,570 --> 00:18:50,150
+each neuron has one or more يعني ممكن يكون dendrite
+
+271
+00:18:50,150 --> 00:18:54,850
+واحد أو متشعب، with which it branches from the cell body
+
+272
+00:18:54,850 --> 00:18:58,990
+to conduct nerve signals towards the cell body of the
+
+273
+00:18:58,990 --> 00:19:04,670
+neuron. طبعاً الـ distal end of dendrites of
+
+274
+00:19:04,670 --> 00:19:08,050
+sensory neurons هي الـ Receptors، لأن هو اللي
+
+275
+00:19:08,050 --> 00:19:12,430
+بيستقبل الـ impulse. طبعاً
+
+276
+00:19:12,430 --> 00:19:16,580
+الوضع بيختلف، بتختلف في الـ structure بتاعتها أو الـ
+
+277
+00:19:16,580 --> 00:19:20,540
+classification حسب الـ structure والـ function
+
+278
+00:19:20,540 --> 00:19:25,540
+الـ structural classification by number of processes
+
+279
+00:19:25,540 --> 00:19:30,060
+extended from. ممكن unipolar أو bipolar أو
+
+280
+00:19:30,060 --> 00:19:35,420
+multipolar. الرسم هنا بيوضح أكتر. الـ unipolar فيه one
+
+281
+00:19:35,420 --> 00:19:40,050
+process، and زي الـ ganglia، يعني في عندنا process
+
+282
+00:19:40,050 --> 00:19:44,930
+واحد زي ما إحنا شايفينه هنا بيطلع فوق وتحت، أما الـ
+
+283
+00:19:44,930 --> 00:19:50,910
+bipolar فبيأخد فوق وتحت، فيه إتجاهين، زي الـ ear والـ
+
+284
+00:19:50,910 --> 00:19:54,290
+nose، الـ neurons اللي بتكون في الـ ear والـ nose
+
+285
+00:19:54,290 --> 00:19:57,350
+والـ eye. أما الـ multipolar فهو الـ neurons of the
+
+286
+00:19:57,350 --> 00:20:01,670
+central nervous system، has many processes. Most
+
+287
+00:20:01,670 --> 00:20:06,650
+neurons of the central nervous system. طبعاً هذا بعد
+
+288
+00:20:06,650 --> 00:20:11,850
+التوضيح، الصورة بتوضح بعض الـ neurons للـ
+
+289
+00:20:11,850 --> 00:20:17,630
+peripheral nervous system. كيف في عندنا أحياناً في
+
+290
+00:20:17,630 --> 00:20:21,790
+حاجة اسمها interneurons، وفي عندنا sensory neurons
+
+291
+00:20:21,790 --> 00:20:26,290
+وفي عندنا motor neurons. الـ sensory هي الـ afferent
+
+292
+00:20:26,290 --> 00:20:31,210
+اللي بترسل الإشارة إلى الـ central nervous system، و
+
+293
+00:20:31,210 --> 00:20:36,150
+معظمها unipolar، وبعضها من الـ bipolar. أما الـ inter-
+
+294
+00:20:36,150 --> 00:20:39,370
+neurons فعادة بتكون multipolar، لأنها linked
+
+295
+00:20:39,370 --> 00:20:43,890
+neurons together. أما الـ motor neurons فهي multi-
+
+296
+00:20:43,890 --> 00:20:47,030
+polar، وcarry impulses away from the central
+
+297
+00:20:47,030 --> 00:20:52,870
+nervous system to the effector، يعني للعضلات وللـ
+
+298
+00:20:52,870 --> 00:21:00,710
+other components. وهذه صورة توضيحية لبعض الـ...
+
+299
+00:21:06,350 --> 00:21:11,330
+الـ neurons زي الـ sensory والـ motor. الـ motor هتجينا
+
+300
+00:21:11,330 --> 00:21:15,210
+الحركة هتجينا من الـ skeletal، هتروح للـ skeletal
+
+301
+00:21:15,210 --> 00:21:19,510
+muscle. أما الـ sensory ممكن تجينا من أي receptors
+
+302
+00:21:19,510 --> 00:21:24,190
+ثانية وحتى  تتحول عن طريق الـ interneuron عشان
+
+303
+00:21:24,190 --> 00:21:27,990
+ترجع الحركة عن طريق spinal cord لو كانت reflex
+
+304
+00:21:30,600 --> 00:21:38,980
+وهذا شكل بيوضح كيف بتصير عملية الـ... الـ reflex لو
+
+305
+00:21:38,980 --> 00:21:43,700
+شكنا دبوس، على طول بتروح الإشارة عن طريق الـ spinal
+
+306
+00:21:43,700 --> 00:21:47,020
+cord، أو على الـ sensory nerve على الـ spinal cord، و
+
+307
+00:21:47,020 --> 00:21:53,460
+فورا بترجع على الـ... الـ... الإصبع مثلاً حتى يبتعد
+
+308
+00:21:53,460 --> 00:21:54,660
+عن الدبوس
+
+309
+00:22:03,400 --> 00:22:06,900
+طبعاً الـ nerves هي عبارة عن organs of the
+
+310
+00:22:06,900 --> 00:22:11,440
+peripheral nervous system. الـ nerves، عادة في عندنا
+
+311
+00:22:11,440 --> 00:22:14,740
+sensory nerves اللي هي بتاخد الإشارة، convey
+
+312
+00:22:14,740 --> 00:22:17,520
+sensory information to the central nervous system،
+
+313
+00:22:17,520 --> 00:22:21,380
+وعكسها على طول في عندنا الـ motor nerves اللي بتعمل
+
+314
+00:22:21,380 --> 00:22:25,160
+convey للـ motor impulses للـ muscles and the
+
+315
+00:22:25,160 --> 00:22:28,160
+glands. وفي عندنا الـ mixed اللي بيكون منها sensory
+
+316
+00:22:28,160 --> 00:22:34,700
+و motor، بتكون تجمع بين sensory and motor.الأكسونات تنتهي
+
+317
+00:22:34,700 --> 00:22:39,220
+عندما تتواصل مع نيرونات أخرى أو عضو أو عضو  أو عضو
+
+318
+00:22:39,220 --> 00:22:40,340
+(repeated phrase removed)
+
+319
+00:22:40,340 --> 00:22:41,320
+(repeated phrase removed)
+
+320
+00:22:41,320 --> 00:22:42,700
+(repeated phrase removed)
+
+321
+00:22:42,700 --> 00:22:45,840
+(repeated phrase removed)
+
+322
+00:22:45,840 --> 00:22:46,220
+(repeated phrase removed)
+
+323
+00:22:46,220 --> 00:22:47,740
+(repeated phrase removed)
+
+324
+00:22:47,740 --> 00:22:56,900
+(repeated phrase removed)
+
+325
+00:22:56,900 --> 00:23:00,880
+طيب، ده إيش الـ organization بتاع الـ nerve أو الـ... الـ... الـ
+
+326
+00:23:00,880 --> 00:23:07,260
+neuron؟ في كل neuron بيحاط في... فيه غشاء
+
+327
+00:23:07,260 --> 00:23:09,840
+الـ epineurium، perineurium، endoneurium
+
+328
+00:23:12,490 --> 00:23:17,110
+أما الـ perineurium فهو يحيط بالـ fascicles، مجموعة من الـ
+
+329
+00:23:17,110 --> 00:23:20,190
+nerves. وفي الـ endoneurium اللي هو يحيط بالـ
+
+330
+00:23:20,190 --> 00:23:23,750
+individual axon of the nerve، يعني الـ axon اللي
+
+331
+00:23:23,750 --> 00:23:29,260
+واحد، يحيط به الـ endoneurium. مجموعة من الـ axons يحيط بها الـ
+
+332
+00:23:29,260 --> 00:23:34,920
+perineurium. أما الغشاء الخارجي اللي بيحيط بكل
+
+333
+00:23:34,920 --> 00:23:39,220
+الـ nerve فبيسمى الـ epineurium. هي الصورة أكتر
+
+334
+00:23:39,220 --> 00:23:43,930
+بتوضح الـ axon نفسه وكيف محاط بالـ endoneurium
+
+335
+00:23:43,930 --> 00:23:47,970
+ومجموعة منهم... مجموعة من الـ axons محاطة
+
+336
+00:23:47,970 --> 00:23:52,970
+بالـ perineurium، والنيرف نفسه محاط بالـ epineurium. طب عملية
+
+337
+00:23:52,970 --> 00:23:57,290
+الـ repair كيف بتصير؟ الـ mature neurons are
+
+338
+00:23:57,290 --> 00:24:00,830
+incapable of cell division. طبعاً مافيش division
+
+339
+00:24:00,830 --> 00:24:04,530
+عشان هيك أي damage للـ nervous system بيكون
+
+340
+00:24:04,530 --> 00:24:08,380
+permanent. وقتها ممكنش نعمل repair. هنشوف الـ
+
+341
+00:24:08,380 --> 00:24:11,300
+neurons have a limited capacity to repair themselves،
+
+342
+00:24:11,300 --> 00:24:14,280
+الـ nerve fibers can be repaired إذا كان الـ damage
+
+343
+00:24:14,280 --> 00:24:18,740
+is not extensive، مش كتير كبير، الـ cell body والـ
+
+344
+00:24:18,740 --> 00:24:21,700
+neuron لما يكونوا intact، اللي هو الغشاء المحيط في الـ
+
+345
+00:24:21,700 --> 00:24:25,180
+neuron بيكون لسه intact، والـ scarring is not
+
+346
+00:24:25,180 --> 00:24:31,180
+extensive، مافيش عندنا عملية scarring أو أن دي موجودة
+
+347
+00:24:31,180 --> 00:24:34,740
+على الـ neuron. الـ peripheral nerve، الـ regeneration
+
+348
+00:24:34,740 --> 00:24:42,400
+of peripheral nervous system axons is invaluable
+
+349
+00:24:42,400 --> 00:24:46,780
+in response to cut and trauma. طبعاً أي axon ممكن إنه يصيب
+
+350
+00:24:46,780 --> 00:24:50,320
+بالتروما، الـ damage of the axon can regenerate if
+
+351
+00:24:50,320 --> 00:24:53,680
+some of its sheath remains، إذا لسه الـ sheath بتاع الـ
+
+352
+00:24:53,680 --> 00:24:58,280
+axon لسه موجود، فيه فرصة إنه يصير فيه regeneration،
+
+353
+00:24:58,280 --> 00:25:02,560
+وبيعتمد على الـ factors، amount of damage، والـ
+
+354
+00:25:02,560 --> 00:25:07,240
+Neurolemmal Sheath Secretion of Nerve Growth Factor
+
+355
+00:25:07,240 --> 00:25:11,920
+طبعاً بتشير إلى أعضاء الأكسون السليمة والتقرير بين
+
+356
+00:25:11,920 --> 00:25:17,300
+موقع الأكسون التالف والأعضاء، يعني المسافة ما بين
+
+357
+00:25:17,300 --> 00:25:20,690
+التلف اللي صار وما بين الـ organ، وهي اللي هتكون
+
+358
+00:25:20,690 --> 00:25:24,510
+هي اللي بتحدد، هنشوفها قدام بالصورة. طبعاً الـ regeneration
+
+359
+00:25:24,510 --> 00:25:29,310
+عملية صعبة شوية و a very slow process، يعني تقريباً في
+
+360
+00:25:29,310 --> 00:25:36,070
+الإنسان، growth rate 1.5 mm، يعني واحد ونصف
+
+361
+00:25:36,070 --> 00:25:40,270
+millimeter per day، في الإنسان، أسرع في حالات
+
+362
+00:25:40,270 --> 00:25:47,500
+الأرانب. لكن إذا كانت هذه العملية بتكون أسرع أو
+
+363
+00:25:47,500 --> 00:25:50,660
+بتكون بهذا الريتم إذا كان فيه عندنا... مافيش عندنا
+
+364
+00:25:50,660 --> 00:25:53,960
+infection، no infection، و partial cut of the
+
+365
+00:25:53,960 --> 00:25:58,140
+axon، مش complete cut. هذا يعني أن neurolemma is
+
+366
+00:25:58,140 --> 00:26:01,740
+intact. فـ regeneration بتبدأ في الـ nerve cell by
+
+367
+00:26:01,740 --> 00:26:05,900
+resuming its normal shape and content. طبعاً الـ nerve
+
+368
+00:26:05,900 --> 00:26:10,740
+fiber، الـ axon، بالـ sprouts from the cell body
+
+369
+00:26:10,740 --> 00:26:18,220
+will grow. بتصير عندنا the entire neurolemmal
+
+370
+00:26:18,220 --> 00:26:23,080
+tube and extends to the distal cut end of the
+
+371
+00:26:23,080 --> 00:26:26,860
+nerve. هلقيت هنشوف هذا بالصور أكتر، نشوف الصور رقم
+
+372
+00:26:26,860 --> 00:26:30,200
+واحد. صار في عندنا الـ trauma على الـ axon، لكن الـ
+
+373
+00:26:30,200 --> 00:26:35,520
+sheath لسه موجود، وفي عندنا مسافة بين
+
+374
+00:26:35,520 --> 00:26:39,580
+الـ muscle أو الـ skeletal muscle. فـ اللي بتصير
+
+375
+00:26:39,580 --> 00:26:43,780
+المرحلة الثانية، إنه بتصير الـ end اللي موجودة عندنا
+
+376
+00:26:44,100 --> 00:26:48,960
+الـ end of the axon بتصير swollen وبتصير كده
+
+377
+00:26:48,960 --> 00:26:52,840
+متورمة زي أي حالة من الـ inflammation بتصير، وما
+
+378
+00:26:52,840 --> 00:26:56,560
+بعدها هنا إيش بيصير فيه؟ بيصير فيه degeneration
+
+379
+00:26:56,560 --> 00:27:03,430
+بعد هيك للمور،  (repeated phrase removed)
+
+380
+00:27:03,430 --> 00:27:06,850
+(repeated phrase removed)
+
+381
+00:27:06,850 --> 00:27:08,410
+(repeated phrase removed)
+
+382
+00:27:08,410 --> 00:27:09,170
+(repeated phrase removed)
+
+383
+00:27:09,170 --> 00:27:09,750
+(repeated phrase removed)
+
+384
+00:27:09,750 --> 00:27:13,530
+(repeated phrase removed)
+
+385
+00:27:13,530 --> 00:27:25,630
+(repeated phrase removed)
+
+386
+00:27:29,740 --> 00:27:33,700
+باسم الـ Neuroglia، هي عبارة عن الـ connective
+
+387
+00:27:33,700 --> 00:27:37,740
+tissue في الـ central nervous system، طبعاً بدل الـ
+
+388
+00:27:37,740 --> 00:27:41,360
+connective tissue فيه حاجة اسمها Neuroglia. الـ
+
+389
+00:27:41,360 --> 00:27:46,720
+Neuroglia عبارة عن cells موجودة، supporting tissue أو
+
+390
+00:27:46,720 --> 00:27:51,340
+supporting cells، بين الـ neurons of the
+
+391
+00:27:51,340 --> 00:27:55,460
+central nervous system. طبعاً إلها أسماء شوية صعبة،
+
+392
+00:27:55,460 --> 00:27:56,000
+زي الـ
+
+393
+00:27:59,420 --> 00:28:09,020
+Oligodendrocytes، و Astrocytes، و الـ ependymal cells. طبعاً
+
+394
+00:28:09,020 --> 00:28:13,700
+هنا صورة أوضح بتوضح كيف بتصير عملية الـ support
+
+395
+00:28:13,700 --> 00:28:17,260
+اللي موجودة وبتوصل  الـ axons مع بعض عن طريق الـ
+
+396
+00:28:17,260 --> 00:28:23,040
+Oligodendrocytes اللي هي دي، وكيف الـ Astrocytes
+
+397
+00:28:23,040 --> 00:28:27,140
+هنا بتساعد على التماسك
+
+398
+00:28:28,440 --> 00:28:32,600
+للنيورونات مع بعضها. طبعاً وظيفتها تعمل support،
+
+399
+00:28:32,600 --> 00:28:36,440
+similar to the function of connective tissue. بتكون
+
+400
+00:28:36,440 --> 00:28:40,120
+myelin sheaths around the axon، وهو عبارة عن
+
+401
+00:28:40,120 --> 00:28:44,360
+insulators، بتعمل عملية عزل بين الـ neurons، و
+
+402
+00:28:44,360 --> 00:28:49,360
+nutritive بتغذيها، بتعمل defense against
+
+403
+00:28:49,360 --> 00:28:53,620
+inflammation، وبتساعد في عملية الـ regeneration. وهذه
+
+404
+00:28:53,620 --> 00:28:5
\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..6e10da8ba5f4c7de43bdef8af2059e5a406c35be
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8_postprocess.srt
@@ -0,0 +1,1680 @@
+1
+00:00:05,150 --> 00:00:07,690
+بسم الله الرحمن الرحيم محاضرتنا اليوم عن ال
+
+2
+00:00:07,690 --> 00:00:10,670
+nervous system و مكونات ال nervous system و نشوف
+
+3
+00:00:10,670 --> 00:00:15,970
+الخلية المكونة ل nervous system و تقسيماته طبعا
+
+4
+00:00:15,970 --> 00:00:19,410
+احنا معروف ان ال nervous system هو و ال endocrine
+
+5
+00:00:19,410 --> 00:00:23,980
+system هم اللي بنظموا عملية ال ..في وظائف الجسم
+
+6
+00:00:23,980 --> 00:00:28,240
+كلها وبنعرف أن الجسم أول ما بيتعرض لأي insult أو
+
+7
+00:00:28,240 --> 00:00:32,740
+بتعرض لخوف أو بتعرض لأدب بيكون الأسرع إشي في
+
+8
+00:00:32,740 --> 00:00:35,600
+التصرف هو ال nervous system ويا ليه طبعا ال
+
+9
+00:00:35,600 --> 00:00:38,540
+endocrine system اللي بيعمل بيحافظ على ال
+
+10
+00:00:38,540 --> 00:00:43,900
+hemostasis تبع الجسم يبقى هنتعرف على مكونات ال
+
+11
+00:00:43,900 --> 00:00:47,150
+nervous system هو في عندنا نوعينمن ال nervous
+
+12
+00:00:47,150 --> 00:00:49,430
+system في عندنا ال central nervous system و عندنا
+
+13
+00:00:49,430 --> 00:00:53,790
+ال peripheral nervous system ال central nervous
+
+14
+00:00:53,790 --> 00:00:56,670
+system هو عبارة عن ال brain and spinal cord و ال
+
+15
+00:00:56,670 --> 00:00:59,590
+peripheral nervous system هو عبارة عن ال nerves
+
+16
+00:00:59,590 --> 00:01:03,930
+اللى بتطلع من ال spinal cord أو من ال brain إلى
+
+17
+00:01:03,930 --> 00:01:09,200
+أجزاء الجسم كلهاطبعا ايش ال function احنا بنعرف
+
+18
+00:01:09,200 --> 00:01:13,000
+انه انا ال central nervous system بيكون في عندي
+
+19
+00:01:13,000 --> 00:01:16,940
+الو two functions اول حاجة ال sensory و في ..
+
+20
+00:01:16,940 --> 00:01:20,360
+three functions sorry ال sensory function و ال
+
+21
+00:01:20,360 --> 00:01:23,600
+motor function و ال integration function طبعا كتير
+
+22
+00:01:23,600 --> 00:01:27,500
+مهم ال link بين هدولة التلاتة functions لإنه إذا
+
+23
+00:01:27,500 --> 00:01:31,320
+كنا بنحس مابنقدرش نتصرف فطبعا بيصير في عندنا مشكلة
+
+24
+00:01:31,320 --> 00:01:35,020
+إذا كنا مافيش عندنا إحساس فهذه مشكلة طبعا أكبر لإن
+
+25
+00:01:35,020 --> 00:01:38,900
+ممكن واحد يتعرضلمخاطر هلقيت اذا انا حاسة انه انا
+
+26
+00:01:38,900 --> 00:01:42,700
+حط ايدي علي إيش سخن و هذا و حاسة ان السخن انا مش
+
+27
+00:01:42,700 --> 00:01:46,520
+قادرة ارفع ايدي عنها فهذه هتأدي الى الحرق تمام؟
+
+28
+00:01:46,520 --> 00:01:51,360
+لكن كمان لو انا كنتأنا عندي حركة كويسة لكن فيش
+
+29
+00:01:51,360 --> 00:01:54,320
+عندي إحساس فانا إيدي موجودة على إشر السخن على
+
+30
+00:01:54,320 --> 00:01:57,560
+دفاية أو على بوداكاز أو على تنجرة فانا هنحرقه مش
+
+31
+00:01:57,560 --> 00:02:02,300
+هتوصلي الإشارة للدماغ تقولني إن في عندي مشكلة
+
+32
+00:02:02,300 --> 00:02:07,020
+فهتأدي لحرق ال integration فانا ممكن أحط إيدي على
+
+33
+00:02:07,020 --> 00:02:10,600
+إشر السخن لكن مايوصل التفسير هذا للدماغ اللي على
+
+34
+00:02:10,600 --> 00:02:15,250
+أساسه هيصير التصرف بعد هيكو قوله ارفع ايدك عن ال
+
+35
+00:02:15,250 --> 00:02:20,030
+.. ال .. الدفاية او عن ال .. قشر السخن فيبقى هدول
+
+36
+00:02:20,030 --> 00:02:23,070
+التلاتة components لازم تكون عشان انا اخد good
+
+37
+00:02:23,070 --> 00:02:25,790
+function لازم يكونوا عندى ال sensory و ال motor و
+
+38
+00:02:25,790 --> 00:02:29,530
+ال integrative function intactإيش هي ال sensory؟
+
+39
+00:02:29,530 --> 00:02:32,330
+فهي عبارة عن sensory receptors gathering
+
+40
+00:02:32,330 --> 00:02:36,670
+information، ال information هذه بتروح وين؟ أنا
+
+41
+00:02:36,670 --> 00:02:40,230
+باخد، طبعا في عندي ال special senses مثلا زي
+
+42
+00:02:40,230 --> 00:02:43,590
+البصر، أنا ماشية في الطريق، في قدامي حفرة، في
+
+43
+00:02:43,590 --> 00:02:47,170
+قدامي درج، فأنا بيعطيني order، بوصل ل .. بروح
+
+44
+00:02:47,170 --> 00:02:50,150
+للدماغ، أول إشي الإشارة بتروح لدماغ، بتقول إن في
+
+45
+00:02:50,150 --> 00:02:54,030
+هنا عطبة، خلّي بالك لما تنزلي أحسنتتوقعه فبيعطي
+
+46
+00:02:54,030 --> 00:02:57,890
+إشارة لأول إشي بتروح إشارة عندك بتعمل
+
+47
+00:02:57,890 --> 00:03:00,810
+interpretation بتعمل interpretation بتقوله هنا في
+
+48
+00:03:00,810 --> 00:03:04,290
+عطبة هنا في حفرة ابعدي عنها فبيجي ال order ل
+
+49
+00:03:04,290 --> 00:03:07,830
+skeletal system عشان هو يتسرى فيبقى sensory
+
+50
+00:03:07,830 --> 00:03:11,190
+receptors gathering information بتاخد ال
+
+51
+00:03:11,190 --> 00:03:16,850
+information من البيئة المحيطة بترسلها لمين ل ال
+
+52
+00:03:16,850 --> 00:03:20,990
+central nervous system أو ل ال brainفي بعض الحركات
+
+53
+00:03:20,990 --> 00:03:23,970
+بتكون reflex يعني مابتوصل لليبران يعني انا لو حطت
+
+54
+00:03:23,970 --> 00:03:26,650
+ايدي على مسكة فاتحت ال microwave بدي اخد الصحن
+
+55
+00:03:26,650 --> 00:03:30,450
+لقيته سخن بارميه لأنه ماوصلش هذه reflex على طول
+
+56
+00:03:30,450 --> 00:03:34,730
+انا حسيت انه سخن automatic رميته و حاميت نفسي فهذه
+
+57
+00:03:34,730 --> 00:03:38,090
+في بعض الإشارات دعست على الدبوس دعست على الدبوس
+
+58
+00:03:38,090 --> 00:03:42,830
+هذا لسه أعلى من وصل الإشارة لدماغ منكون الدبوس خرق
+
+59
+00:03:42,830 --> 00:03:46,250
+رجلنا لأ هو على طول فورا انت بتروح ترفع احنا بنقول
+
+60
+00:03:46,250 --> 00:03:51,110
+بنرفع رجلنا عن الدبوس هذه في حالةإنه لو صار الأمر
+
+61
+00:03:51,110 --> 00:03:53,810
+preference أما ال integration فهي ال sensor و ال
+
+62
+00:03:53,810 --> 00:03:57,310
+information used to create ال sensation و كمان ال
+
+63
+00:03:57,310 --> 00:04:01,110
+memory و ال thoughts و ال decisions فهذه كلها أمور
+
+64
+00:04:01,110 --> 00:04:07,990
+بتحتاج ل interpretation أو ترجمة فهي integrated
+
+65
+00:04:07,990 --> 00:04:14,590
+functionأما ال motor function فبتكلم عن ال action
+
+66
+00:04:14,590 --> 00:04:18,730
+أنا بدي أبعد هنا لإنه في هنا حفرة، أنا بدي أرفع
+
+67
+00:04:18,730 --> 00:04:22,070
+إيدي لإنه هذا الاشي سخن، أنا والله بفطلع إنها
+
+68
+00:04:22,070 --> 00:04:27,150
+والله في سيارة جادة شقطع الشارع، تمام؟ فهذه إبراعا
+
+69
+00:04:28,010 --> 00:04:31,970
+عملية ال integration ما بين ال sensory و ما بين ال
+
+70
+00:04:31,970 --> 00:04:37,070
+.. ال motor و بعدين هي اللي بتعطينا التفسير لظواهر
+
+71
+00:04:37,070 --> 00:04:41,230
+اللي حولنا أما ال motor لأ ال motor فهي بتعطيني
+
+72
+00:04:41,230 --> 00:04:45,410
+effort بتدوي السير على طول انا ال impulse هذه
+
+73
+00:04:45,410 --> 00:04:50,170
+بتقول ارفع ايدك ميل على اليمين ميل على اليسار ابعد
+
+74
+00:04:50,170 --> 00:04:54,430
+واقفطبعا ال organization of the nervous system
+
+75
+00:04:54,430 --> 00:04:59,150
+detect .. ال organized to detect the changes in
+
+76
+00:04:59,150 --> 00:05:02,630
+the internal and external environment يعني ال
+
+77
+00:05:02,630 --> 00:05:06,550
+nervous system بس ما بتنظر بيعطيني مؤشرات على
+
+78
+00:05:06,550 --> 00:05:10,430
+البيئة اللي حواليا أو إشارات لأ كمان internally
+
+79
+00:05:10,430 --> 00:05:13,910
+إيش بيصير و لأ أنا حاسس حالي سخن، أنا حاسس حالي
+
+80
+00:05:13,910 --> 00:05:17,930
+شوبان، أنا حاسس حالي جوعان، أنا حاسس حالي أتشان
+
+81
+00:05:17,930 --> 00:05:22,490
+كمانand initiate appropriate response طب الله انا
+
+82
+00:05:22,490 --> 00:05:26,470
+جعانى بفضل روح اكل انا عشان بدي روح اشرب انا والله
+
+83
+00:05:26,470 --> 00:05:30,890
+حاسس حالة حران بدي اروح او افقد دم روحها او بدي
+
+84
+00:05:30,890 --> 00:05:35,990
+اغير ملابسي او بدي اخد دوش او whateverطبعا ال sub
+
+85
+00:05:35,990 --> 00:05:40,050
+divisions لل system في عندنا او ال central nervous
+
+86
+00:05:40,050 --> 00:05:43,150
+system أو في عندنا ال peripheral nervous system ال
+
+87
+00:05:43,150 --> 00:05:45,630
+central nervous system عبارة عن ال brain and
+
+88
+00:05:45,630 --> 00:05:52,150
+spinal cord طبعا هو إيش وظيفته integratesensor
+
+89
+00:05:52,150 --> 00:05:55,650
+information evaluate it وكمان بيعطينا ال response
+
+90
+00:05:55,650 --> 00:06:01,570
+او outgoing response بالظبط زي ما انا قلت من الاول
+
+91
+00:06:01,570 --> 00:06:05,230
+انا حسيت هنا هذا اشي سخن راح لدماغ اللي والله هنا
+
+92
+00:06:05,230 --> 00:06:08,690
+في حاجة سخنة ابعدي عنها فبيجيني ال order اني انا
+
+93
+00:06:08,690 --> 00:06:12,430
+اشيل ايدي عنهاطبعا أما ال peripheral nervous
+
+94
+00:06:12,430 --> 00:06:15,890
+system فهو بيستقبل من ال brain و بيستقبل من ال
+
+95
+00:06:15,890 --> 00:06:19,870
+spinal cord ال cranial nerve بتاخد الأمر لأنها هي
+
+96
+00:06:19,870 --> 00:06:23,950
+في منطقتنا قبل ال spinal cord فبتطلع من ال crania
+
+97
+00:06:23,950 --> 00:06:27,990
+نفسها فبتسمى بتاخد من ال brain ل ال periphery ها
+
+98
+00:06:27,990 --> 00:06:32,350
+دي بتغذي عضلات الفاس و ال swallowing و ال neck
+
+99
+00:06:32,350 --> 00:06:35,830
+accessory ايه مثلا؟أما الـ spinal nerve فهي بتطلع
+
+100
+00:06:35,830 --> 00:06:38,510
+من الـ spinal cord بتروح ل الـ appendicular
+
+101
+00:06:38,510 --> 00:06:41,970
+musculoskeletal system على أساس أنه تعمل ليه تعمل
+
+102
+00:06:41,970 --> 00:06:48,410
+perform ل الحركة وكمان على ال internal organs هانا
+
+103
+00:06:48,410 --> 00:06:54,130
+نبدأ بالصور الموضحة بالأشكال فعنا الصورة هذه بتوضح
+
+104
+00:06:54,130 --> 00:06:58,610
+أنه في عندنا هناالـ brain والـ spinal cord هدوء
+
+105
+00:06:58,610 --> 00:07:01,570
+الـ central nervous system وفيه إنها ال cranial
+
+106
+00:07:01,570 --> 00:07:08,570
+nerve و ال spinal nerve اللي هي بتغذي ال periphery
+
+107
+00:07:08,570 --> 00:07:11,450
+of the body
+
+108
+00:07:13,130 --> 00:07:18,170
+طبعا فيه هنا sensory divisions للبرفيرال نيرفي،
+
+109
+00:07:18,170 --> 00:07:21,250
+هنا sensory و في عندنا motor و كمان ال motor
+
+110
+00:07:21,250 --> 00:07:27,850
+بتنقسم ل somatic and autonomic nervous system ال
+
+111
+00:07:27,850 --> 00:07:31,370
+sensory طبعا بتاخد ال pick up sensory information
+
+112
+00:07:31,370 --> 00:07:36,190
+and deliver it to the central nervous system،
+
+113
+00:07:36,190 --> 00:07:42,550
+بتاخد المعلومة أو الإشارةعن طريق الجسم وبترسلها لل
+
+114
+00:07:42,550 --> 00:07:45,930
+central nervous system سواء لل spinal cord اللى
+
+115
+00:07:45,930 --> 00:07:50,390
+بيرفعها عن طريق ال elevators تبعته إلى الدماغ فى
+
+116
+00:07:50,390 --> 00:07:54,370
+أن ال motor divisions بتعطينى information عن ال
+
+117
+00:07:54,370 --> 00:07:59,670
+muscles and gland يعنى بتعطينى حالة العضلات وحالة
+
+118
+00:07:59,670 --> 00:08:05,280
+ال gland اللى موجودة فى الجسمال motor system اللي
+
+119
+00:08:05,280 --> 00:08:08,240
+بينقسم ل somatic و autonomous ال somatic هو اللي
+
+120
+00:08:08,240 --> 00:08:12,700
+بروح لل muscles system اللي بعملي الحركة يعني هو
+
+121
+00:08:12,700 --> 00:08:17,440
+اللي بقولي ابعدي روحي تعالي امسكي اشربي امسكي
+
+122
+00:08:17,440 --> 00:08:21,420
+الكباية العضلات هي اللي بتعمل هذا الشغل اما ال
+
+123
+00:08:21,420 --> 00:08:25,640
+autonomous فهوكمان اللي هو جهاز اللا إرادي بمعنى
+
+124
+00:08:25,640 --> 00:08:29,020
+إنه أنا ما بتحكم في عضلة القلب أقولها دقي وما
+
+125
+00:08:29,020 --> 00:08:32,000
+أدقيش تمام؟ ال glance أنا ما بتحكم بالإفرازات
+
+126
+00:08:32,000 --> 00:08:38,600
+تبعتها لكن في nervous system بيتحكم حقيقي فيها
+
+127
+00:08:38,600 --> 00:08:41,580
+carried information to the smooth muscle و ال
+
+128
+00:08:41,580 --> 00:08:46,120
+cardiac muscle and the glance طبعا هذا الرسم
+
+129
+00:08:46,120 --> 00:08:50,220
+التوضيحي بوضح لنا حالة الأسرار
+
+130
+00:08:53,990 --> 00:09:00,310
+أحنا أين روحنا؟ هنا، عندنا الـ brain زي ما أحنا
+
+131
+00:09:00,310 --> 00:09:05,090
+شايفين و ال spinal cord مثل عامله ال spinal nerve،
+
+132
+00:09:05,090 --> 00:09:08,510
+طبعا في عندنا ال sensory receptors هي اللي بترفع
+
+133
+00:09:08,510 --> 00:09:12,170
+لـ brain، في عندنا ال motor اللي هي ال somatic
+
+134
+00:09:12,170 --> 00:09:14,830
+اللي بتروح على ال skeletal muscle و في عندنا ال
+
+135
+00:09:14,830 --> 00:09:18,290
+anatomic اللي بتروح على السموت وال cardiac and
+
+136
+00:09:18,290 --> 00:09:24,300
+glandsالـ الـ systems according to the type of
+
+137
+00:09:24,300 --> 00:09:28,160
+organs they innervate في عندنا الـ somatic الـ
+
+138
+00:09:28,160 --> 00:09:30,920
+somatic motor و في somatic sensory طبيعي أنه
+
+139
+00:09:30,920 --> 00:09:35,480
+الجسدية أو خلال العصاب الجسدية ال somatic motor
+
+140
+00:09:35,480 --> 00:09:38,560
+division carried information to the somatic
+
+141
+00:09:38,560 --> 00:09:42,380
+effectors اللي هي ال skeletal مثلا أما ال sensory
+
+142
+00:09:42,380 --> 00:09:46,780
+divisions فهي carried feedback تأخد ال feedback من
+
+143
+00:09:46,780 --> 00:09:52,740
+العضلاتto the somatic integration
+
+144
+00:09:52,740 --> 00:09:56,560
+center of the central nervous يعني الموتر هي اللي
+
+145
+00:09:56,560 --> 00:10:02,300
+بترسل و ال sensor هي اللي بتستقبل هذا باختصار أما
+
+146
+00:10:02,300 --> 00:10:06,200
+ال atomic nervous system عبارة عن efferent
+
+147
+00:10:06,200 --> 00:10:09,810
+divisionsالـ different divisions هذه فيها الـ
+
+148
+00:10:09,810 --> 00:10:13,150
+sympathetic والبارع sympathetic وظفتها carried
+
+149
+00:10:13,150 --> 00:10:15,670
+information to the autonomic and visceral
+
+150
+00:10:15,670 --> 00:10:19,270
+effectors اللي هي smooth and cardiac muscle and
+
+151
+00:10:19,270 --> 00:10:23,350
+gland هاي ال sympathetic divisions عبارة عن اللي
+
+152
+00:10:23,350 --> 00:10:29,160
+هو ال .. يعني فلان نقول وسيلة الدفع عن الجسمعادة
+
+153
+00:10:29,160 --> 00:10:32,760
+بتعمل preparation to the body to deal with any
+
+154
+00:10:32,760 --> 00:10:37,500
+dehydrating to the internal environment يعني إذا
+
+155
+00:10:37,500 --> 00:10:40,860
+كان أي إشي بيشكل خطر فعلى طول ال sympathetic
+
+156
+00:10:40,860 --> 00:10:48,100
+system هو بيشتغل حتى تتمكن من الهروب من الخطر عادة
+
+157
+00:10:48,620 --> 00:10:51,220
+أما الـ Parasympathetic System فهذا بيشتغل في الـ
+
+158
+00:10:51,220 --> 00:10:55,000
+Rest، هذا هو مرتاح هو مرتاح الشخص قنايم اللي
+
+159
+00:10:55,000 --> 00:10:57,820
+بيشتغل coordinate the body's normal resting
+
+160
+00:10:57,820 --> 00:11:01,580
+activity الـ Visceral Sensory Divisions carried في
+
+161
+00:11:01,580 --> 00:11:04,440
+كتاب Feedback Information للـ Autonomic
+
+162
+00:11:04,440 --> 00:11:08,840
+Integrating Center of the .. يعني هنا في عندي في
+
+163
+00:11:08,840 --> 00:11:14,900
+كل الفذرة أو الـ Internal Organs فيها Sensoryالـ
+
+164
+00:11:14,900 --> 00:11:19,180
+sensory neurons هذه بترفع ليه على ال autonomous
+
+165
+00:11:19,180 --> 00:11:22,620
+nervous system من ال autonomous nervous system لال
+
+166
+00:11:22,620 --> 00:11:27,700
+brain أو لcentral nervous systemتتكلمنا عن الـ
+
+167
+00:11:27,700 --> 00:11:30,940
+afferent and efferent divisions، الـ afferent هي
+
+168
+00:11:30,940 --> 00:11:35,240
+اللي بترفع، هي عبارة incoming sensory pathways هي
+
+169
+00:11:35,240 --> 00:11:38,880
+اللي بترفع ال ways .. هي بترفع لدماج، أما ال
+
+170
+00:11:38,880 --> 00:11:41,460
+efferent فهي اللي بتعطينا العودة، يعني احنا في
+
+171
+00:11:41,460 --> 00:11:45,420
+عندنا elevator ساعد و في عندنا elevator نازل، ال
+
+172
+00:11:45,420 --> 00:11:50,180
+afferent هي المصعد اللي طالع إلى ال brain أما ال
+
+173
+00:11:50,180 --> 00:11:54,080
+efferent هي المصعد اللي نازل من ال brain إلى ال
+
+174
+00:11:54,080 --> 00:11:55,120
+motor pathways
+
+175
+00:11:58,750 --> 00:12:04,470
+طبعا ال components of somatic sensory عادة ال
+
+176
+00:12:04,470 --> 00:12:07,950
+general somatic senses زي ال touch، البان، ال
+
+177
+00:12:07,950 --> 00:12:11,010
+pressure، ال vibration، ال temperature، ال
+
+178
+00:12:11,010 --> 00:12:13,970
+proprioceptions اللي موجود في .. اللي بيعطيني حالة
+
+179
+00:12:13,970 --> 00:12:19,130
+ال .. ال jointsأما ال special senses زي ال test،
+
+180
+00:12:19,130 --> 00:12:23,090
+التدوق و ال vision، ال hearing، ال balance، ال
+
+181
+00:12:23,090 --> 00:12:27,890
+smells، هذه كلها special senses و هي ال sensory as
+
+182
+00:12:27,890 --> 00:12:28,130
+well
+
+183
+00:12:30,970 --> 00:12:34,270
+أما الـ visceral sensory component طبعا ترسمت
+
+184
+00:12:34,270 --> 00:12:38,070
+impulse nerve impulse from the blood vessels to
+
+185
+00:12:38,070 --> 00:12:42,550
+the viscera to the central nervous system يعني
+
+186
+00:12:42,550 --> 00:12:45,710
+بتاخد المعلومات من الviscera أو من blood vessels و
+
+187
+00:12:45,710 --> 00:12:49,550
+بتطلع فيها على الدماغ الvisceral sense primarily
+
+188
+00:12:49,550 --> 00:12:52,630
+include temperature و ال stretch يعني قدش بيصير في
+
+189
+00:12:52,630 --> 00:12:57,190
+stretch في الفذر قدش احنا بنقدر ان نحس اننا نعتمد
+
+190
+00:12:57,190 --> 00:13:02,460
+على كمية ال stretchاللي بتصير في ال organ أما ال
+
+191
+00:13:02,460 --> 00:13:08,660
+motor ففي عندنا طبعا ال motor somatic nervous
+
+192
+00:13:08,660 --> 00:13:12,260
+system هو call back to impulse طبعا مدام motor
+
+193
+00:13:12,260 --> 00:13:16,000
+يبقى بدوره على ال skeletal muscle known as
+
+194
+00:13:16,000 --> 00:13:18,680
+voluntary nervous system وفي الautonomic اللي هو
+
+195
+00:13:18,680 --> 00:13:21,660
+ال involuntary احنا ما بنتحكم في ال internal
+
+196
+00:13:21,660 --> 00:13:25,100
+organs تبعتنا في ال internal organs ريكوليات ال
+
+197
+00:13:25,100 --> 00:13:29,080
+smooth muscle و ال cardiac muscle و ال glandطبعا
+
+198
+00:13:29,080 --> 00:13:32,440
+انربيات ال internal organs كلها رجليات ال smooth
+
+199
+00:13:32,440 --> 00:13:35,360
+muscle و رجليات ال cardiac muscle و ال glands
+
+200
+00:13:35,360 --> 00:13:39,560
+known as involuntary nervous system يعني في عندنا
+
+201
+00:13:39,560 --> 00:13:42,800
+voluntary nervous system و في عندنا involuntary أو
+
+202
+00:13:42,800 --> 00:13:45,900
+somatic nervous system اللي هو ال somatic ال
+
+203
+00:13:45,900 --> 00:13:49,280
+voluntary و ال autonomous هو ال involuntary
+
+204
+00:13:49,280 --> 00:13:52,500
+nervous system لو احنا قرأناها في كتاب تاني او
+
+205
+00:13:52,500 --> 00:13:55,580
+سمعنا عنها فبنعرف ان ال somatic هو ال voluntary و
+
+206
+00:13:55,580 --> 00:13:58,740
+ال autonomous هو ال involuntaryبطريقة دراسة توضيحي
+
+207
+00:13:58,740 --> 00:14:02,620
+للـ function لل organization نلاقي أن ال nervous
+
+208
+00:14:02,620 --> 00:14:06,360
+system ينقسم ل ال sensory affluent divisions هو
+
+209
+00:14:06,360 --> 00:14:10,340
+بيبعت ال information على ال central nervous system
+
+210
+00:14:12,140 --> 00:14:16,140
+وكمان ال motor هو اللي بيرسل من ال central nervous
+
+211
+00:14:16,140 --> 00:14:20,920
+system ل ال periphery ال sensory afferent division
+
+212
+00:14:20,920 --> 00:14:24,180
+بتقسم لل somatic و ال visceral ال somatic بروح على
+
+213
+00:14:24,180 --> 00:14:27,280
+ال musculoskeletal و ال special sense أما ال
+
+214
+00:14:27,280 --> 00:14:30,720
+visceral فهو ال information بيقودها من الفذرة أو
+
+215
+00:14:30,720 --> 00:14:36,280
+الأحشاقانجاز التعبير في بالعربي أما ال motor فبروح
+
+216
+00:14:36,280 --> 00:14:39,140
+ال somatic motor autonomic وقلنا voluntary and
+
+217
+00:14:39,140 --> 00:14:42,440
+involuntary ال voluntary بتحكم بال musculoskeletal
+
+218
+00:14:42,440 --> 00:14:46,140
+أما ال involuntary في ال cardiac و ال smooth and
+
+219
+00:14:46,140 --> 00:14:51,450
+declined muscleروح لـ nerve cells اللي هو الوحدة
+
+220
+00:14:51,450 --> 00:14:55,290
+المكوّنة لـ nervous system هي عبارة عن ال nerve
+
+221
+00:14:55,290 --> 00:14:59,190
+cell two different type of nerve cells في عندنا ال
+
+222
+00:14:59,190 --> 00:15:03,030
+neurons و في عندنا ال glial cells ال neurons هي ال
+
+223
+00:15:03,030 --> 00:15:07,170
+excitable وهي اللي بتعمل transmission ل ال impulse
+
+224
+00:15:07,170 --> 00:15:10,590
+اللي بتساعد على حركة ال impulse يعني هي الكهربا
+
+225
+00:15:10,790 --> 00:15:15,510
+خلّيني أقول هي السلك الكهربائي اللي بيوصل الكهربا
+
+226
+00:15:15,510 --> 00:15:18,230
+من الـ central nervous system للـ peripheral
+
+227
+00:15:18,230 --> 00:15:21,710
+nervous system والعزيزي أما الـ glial cell فهي non
+
+228
+00:15:21,710 --> 00:15:25,690
+excitable يعني ممنوع بتعطيني إشارات كهربائية لكن
+
+229
+00:15:25,690 --> 00:15:29,610
+بتعطيني support و protection زي وظيفة اللي هي ال
+
+230
+00:15:29,610 --> 00:15:32,850
+connective tissue بس لأن ال nervous system بيحتوي
+
+231
+00:15:32,850 --> 00:15:36,690
+على connective tissue فهو بيحتوي على glial cells
+
+232
+00:15:36,690 --> 00:15:40,400
+اللي بتعطيني support و protectionطب ايش ترتيبة
+
+233
+00:15:40,400 --> 00:15:43,700
+لنيرون؟ اي نيرون موجود في عيننا الـ Structural
+
+234
+00:15:43,700 --> 00:15:46,520
+انفاق هو التعريف هو الـ Structural Unfunctional
+
+235
+00:15:46,520 --> 00:15:51,280
+Unit للنرفسيستيم هو بتكون من نيرسل و two processes
+
+236
+00:15:51,280 --> 00:15:57,040
+ال process الأول اللي هو ال Dendrites اللي هو
+
+237
+00:15:57,040 --> 00:16:03,020
+بيستقتل الإشارة و ال Axon اللي هو بيرسل الإشارة
+
+238
+00:16:03,020 --> 00:16:05,180
+طيب
+
+239
+00:16:06,110 --> 00:16:12,070
+إيش ال characteristics تبعت ال neuron هو highly
+
+240
+00:16:12,070 --> 00:16:18,590
+metabolic rates يعني ال ID عنده عالي لكن هو
+
+241
+00:16:18,590 --> 00:16:23,530
+extreme longevity بيعيش فترات قوية وكمان non
+
+242
+00:16:23,530 --> 00:16:28,660
+-metathetic يعني بيصير في انقسامات ال neuronيعني
+
+243
+00:16:28,660 --> 00:16:30,740
+عمنا نعرف إن الخلية بيصير فيها انقسام، الـ neurons
+
+244
+00:16:30,740 --> 00:16:34,440
+لأ ما بيصير فيها انقسام، أه؟ طيب الـ neuron comes
+
+245
+00:16:34,440 --> 00:16:40,040
+in all shapes and sizes share certain basic
+
+246
+00:16:40,040 --> 00:16:43,320
+structure feature اللي هي ال cell body و الaxon
+
+247
+00:16:43,320 --> 00:16:47,020
+and dendritic وهنا زي ما إحنا شايفين ال cell body
+
+248
+00:16:47,020 --> 00:16:50,780
+أي cell body فيها أو بيسموها الـ soma فيها ال
+
+249
+00:16:50,780 --> 00:16:55,260
+nucleusالـ Dendritis هي التشعبات اللي احنا
+
+250
+00:16:55,260 --> 00:17:00,600
+شايفينها هنا ثم الـ Axon فهي الـ لونجة اللي قد
+
+251
+00:17:00,600 --> 00:17:05,520
+حنشوفها الـ process السلبة
+
+252
+00:17:05,520 --> 00:17:14,040
+دي هي الـ center لـ neurons control center طبعا
+
+253
+00:17:14,040 --> 00:17:19,720
+responsible for تستقبل receiving integrating and
+
+254
+00:17:19,720 --> 00:17:25,910
+sending nerve impulseأما تركيبها فهي عبارة عن
+
+255
+00:17:25,910 --> 00:17:31,270
+plasma membrane وفيه cytoplans طبعا أي خلية فيها
+
+256
+00:17:31,270 --> 00:17:35,890
+plasma membrane وcytoplans فيها nucleus with
+
+257
+00:17:35,890 --> 00:17:41,190
+prominent nucleus في عندنا ال chromatophilic
+
+258
+00:17:41,190 --> 00:17:47,110
+substances وفي عندنا every ribosomes تركيب أي خلية
+
+259
+00:17:47,110 --> 00:17:50,030
+أما ال axons فهو عبارة عن
+
+260
+00:17:53,030 --> 00:17:57,310
+أيش؟ بتكون من single process extending from the
+
+261
+00:17:57,310 --> 00:18:06,850
+axon helix بيه بداية بيطلع من ال cell body بتكون
+
+262
+00:18:06,850 --> 00:18:11,670
+زي العنق له sometimes covered by fatty layer اسمه
+
+263
+00:18:11,670 --> 00:18:15,570
+الميالينشيت وهو وظيفته to conduct nerve impulse
+
+264
+00:18:15,570 --> 00:18:21,240
+away from the body of the neuronوهذا شكل ال axon
+
+265
+00:18:21,240 --> 00:18:26,380
+هو long process زي ما احنا شايفينه وهنا احنا زي ما
+
+266
+00:18:26,380 --> 00:18:31,840
+احنا شايفينها ال axon هايلوك اللي هي بداية ال axon
+
+267
+00:18:31,840 --> 00:18:37,060
+وبعدين في عندنا الشيوت وفي عندنا ال node of
+
+268
+00:18:37,060 --> 00:18:41,160
+ramfiers وضيفته
+
+269
+00:18:41,160 --> 00:18:46,570
+انه send the impulseأما الـ Dendrite فهو المستقبل،
+
+270
+00:18:46,570 --> 00:18:50,150
+each neuron has one or more يعني ممكن يكون دندريت
+
+271
+00:18:50,150 --> 00:18:54,850
+واحد أو متشعب with which branch from the cell body
+
+272
+00:18:54,850 --> 00:18:58,990
+conduct nerve signal towards the cell body of the
+
+273
+00:18:58,990 --> 00:19:04,670
+neuron طبعا الـ distal end of dendritis or of
+
+274
+00:19:04,670 --> 00:19:08,050
+sensory neurons هي الـ Receptors لأن هو اللي
+
+275
+00:19:08,050 --> 00:19:12,430
+بيستقبل ال impulse طبعا
+
+276
+00:19:12,430 --> 00:19:16,580
+الوضع مختلفبتختلف في ال structure تبعها أو ال
+
+277
+00:19:16,580 --> 00:19:20,540
+classification حسب ال structure and ال ال function
+
+278
+00:19:20,540 --> 00:19:25,540
+ال structural classification number of processes
+
+279
+00:19:25,540 --> 00:19:30,060
+extended from فممكن unipolar او bipolar او
+
+280
+00:19:30,060 --> 00:19:35,420
+multipolar الرسم هنا بيوضح اكتر ال unipolar في one
+
+281
+00:19:35,420 --> 00:19:40,050
+process andزي ال ganglia يعني في عندنا process
+
+282
+00:19:40,050 --> 00:19:44,930
+واحد زي ما احنا شايفينه هنا بيطلع فوق و تحت أما ال
+
+283
+00:19:44,930 --> 00:19:50,910
+bipolar فبياخد فوق و تحت فيه إتجاهين زي ال ear و
+
+284
+00:19:50,910 --> 00:19:54,290
+ال nose ال neurons اللي بتكون في ال ear و ال nose
+
+285
+00:19:54,290 --> 00:19:57,350
+و ال eye أما ال multipolar فهو ال neurons of the
+
+286
+00:19:57,350 --> 00:20:01,670
+central has many processes of the central most
+
+287
+00:20:01,670 --> 00:20:06,650
+neurons of the central nervous systemطبعا هذا بعد
+
+288
+00:20:06,650 --> 00:20:11,850
+التوضيح الصورة بتوضح بعض ال neurons ل ال
+
+289
+00:20:11,850 --> 00:20:17,630
+peripheral nervous system كيف في عندنا أحيانا في
+
+290
+00:20:17,630 --> 00:20:21,790
+حاجة اسمها inter neurons و في عندنا sensor neurons
+
+291
+00:20:21,790 --> 00:20:26,290
+و في عندنا motor neurons ال sensory هي ال afferent
+
+292
+00:20:26,290 --> 00:20:31,210
+اللي بترسل الإشارة إلى ال central nervous system و
+
+293
+00:20:31,210 --> 00:20:36,150
+معظمها unipolarوبعضها من الـ bipolar أما الـ inter
+
+294
+00:20:36,150 --> 00:20:39,370
+neurons فعادة بتكون multi polar لأنها linked
+
+295
+00:20:39,370 --> 00:20:43,890
+neurons together أما ال motor neurons فهي multi
+
+296
+00:20:43,890 --> 00:20:47,030
+polar و carry impulse away from the central
+
+297
+00:20:47,030 --> 00:20:52,870
+nervous system to the effector يعني للعضلات و لل
+
+298
+00:20:52,870 --> 00:21:00,710
+other components وهذه صورة توضحية لبعض ال ..
+
+299
+00:21:06,350 --> 00:21:11,330
+الـ neurons زي الـ sensory و الموتر الموتر هتجينا
+
+300
+00:21:11,330 --> 00:21:15,210
+الحركة هتجينا من الـ skeletal هتروح للـ skeletal
+
+301
+00:21:15,210 --> 00:21:19,510
+muscle أما الـ sensory ممكن تجينا من أي receptors
+
+302
+00:21:19,510 --> 00:21:24,190
+تانية وحتى التحم عن طريق الـ internal neuron عشان
+
+303
+00:21:24,190 --> 00:21:27,990
+ترجع الحركة عن طريق Spinal cord لو كانت reflex
+
+304
+00:21:30,600 --> 00:21:38,980
+و هذا شكل بيوضح كيف بتصير عملية ال .. ال reflex لو
+
+305
+00:21:38,980 --> 00:21:43,700
+شكنا دبوس على طول بتروح الإشارة عن طريق ال spinal
+
+306
+00:21:43,700 --> 00:21:47,020
+nerve أو على ال sensory nerve على ال spinal cord و
+
+307
+00:21:47,020 --> 00:21:53,460
+فورا بترجع على ال .. ال .. الإصبع مثلا حتى يبتعد
+
+308
+00:21:53,460 --> 00:21:54,660
+عن الدبوس
+
+309
+00:22:03,400 --> 00:22:06,900
+طبعا ال nerves هي عبارة عن organs of the
+
+310
+00:22:06,900 --> 00:22:11,440
+peripheral nervous system ال nerves عادة في عندنا
+
+311
+00:22:11,440 --> 00:22:14,740
+sensory nerves اللي هي بتاخد الإشارة convey
+
+312
+00:22:14,740 --> 00:22:17,520
+sensory information to the central nervous system
+
+313
+00:22:17,520 --> 00:22:21,380
+وعكسها على طول في عندنا ال motor nerves اللي بتعمل
+
+314
+00:22:21,380 --> 00:22:25,160
+convey لل motor impulse على ال muscle and the
+
+315
+00:22:25,160 --> 00:22:28,160
+glands وفي عندنا ال mix اللي بيكون منها sensory
+
+316
+00:22:28,160 --> 00:22:34,700
+بتكون تجمع بين sensory and motorالأكسونات تنتهي
+
+317
+00:22:34,700 --> 00:22:39,220
+عندما تتواصل مع نيرونات أخرى مثل عضو أو عضو عضو أو
+
+318
+00:22:39,220 --> 00:22:40,340
+عضو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+319
+00:22:40,340 --> 00:22:41,320
+أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+320
+00:22:41,320 --> 00:22:42,700
+أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+321
+00:22:42,700 --> 00:22:45,840
+أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+322
+00:22:45,840 --> 00:22:46,220
+أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+323
+00:22:46,220 --> 00:22:47,740
+أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+324
+00:22:47,740 --> 00:22:56,900
+أو عضو أو عضو أو عضو أو عهلأ ده إيش ال
+
+325
+00:22:56,900 --> 00:23:00,880
+organization نفسه لل nerve أو ال .. ال .. ال
+
+326
+00:23:00,880 --> 00:23:07,260
+neuron؟ في كل neuron بي .. بيحاط في .. في عينا
+
+327
+00:23:07,260 --> 00:23:09,840
+الإبي، الموريام، راب، كل
+
+328
+00:23:12,490 --> 00:23:17,110
+أما البري انيرون فهو راب الفاسيكلز مجموعة من ال
+
+329
+00:23:17,110 --> 00:23:20,190
+nerves وفي ال endoneurons اللي هو راب ال
+
+330
+00:23:20,190 --> 00:23:23,750
+individual axon of the nerve يعني ال axon اللي
+
+331
+00:23:23,750 --> 00:23:29,260
+واحد راب ال endoneuronمجموعة من الـ axons رابست by
+
+332
+00:23:29,260 --> 00:23:34,920
+الـ perineuron أما الغشاء الخارجي اللي بيحيط كل
+
+333
+00:23:34,920 --> 00:23:39,220
+الـ neuron فبيسمى الـ epineuron هي الصورة الأكتر
+
+334
+00:23:39,220 --> 00:23:43,930
+بتوضح الـ axon نفسهوكيف محاط بالـ endoneuron
+
+335
+00:23:43,930 --> 00:23:47,970
+ومجموعة منهم .. مجموعة من الـ axons محاط
+
+336
+00:23:47,970 --> 00:23:52,970
+بالبرينيرون والنيرب نفسه محاط بالابنيرون طب عملية
+
+337
+00:23:52,970 --> 00:23:57,290
+ال rebirth كيف تصير ال mature neurons are
+
+338
+00:23:57,290 --> 00:24:00,830
+incapable of cell division طبعا مافيش division
+
+339
+00:24:00,830 --> 00:24:04,530
+عشان هيك أي damage لل nervous system بيكون
+
+340
+00:24:04,530 --> 00:24:08,380
+permanentوقتش ممكنش permanent عيدنا هنشوف ال
+
+341
+00:24:08,380 --> 00:24:11,300
+neurons have limited capacity to repair themselves
+
+342
+00:24:11,300 --> 00:24:14,280
+ال nerve fibers can be repaired إذا كان ال damage
+
+343
+00:24:14,280 --> 00:24:18,740
+is not extensive مش كتير كبير ال cell body و ال
+
+344
+00:24:18,740 --> 00:24:21,700
+neuron لمّا are intact اللي هو غشاء المحاطي في ال
+
+345
+00:24:21,700 --> 00:24:25,180
+neuron بيكون ما زال intact و ال scarring are not
+
+346
+00:24:25,180 --> 00:24:31,180
+okay مافيش عندنا عملية ال scarring أو أن ده موجودة
+
+347
+00:24:31,180 --> 00:24:34,740
+على ال neuron ال peripheral nerveالـ regeneration
+
+348
+00:24:34,740 --> 00:24:42,400
+of peripheral nervous system axons are invaluable
+
+349
+00:24:42,400 --> 00:24:46,780
+to cut and trauma طبعا أي axon ممكن انه يصير انصاب
+
+350
+00:24:46,780 --> 00:24:50,320
+بتراما ال damage of the axon can regenerate if
+
+351
+00:24:50,320 --> 00:24:53,680
+some of your gamma remains إذا لسه ال sheet تبع ال
+
+352
+00:24:53,680 --> 00:24:58,280
+axon لسه موجود ففيه فرصة انه يصير فيه regeneration
+
+353
+00:24:58,280 --> 00:25:02,560
+وبيعتمد على ال factor amount of damageوالـ
+
+354
+00:25:02,560 --> 00:25:07,240
+Neuroliminal Site Secretion of Nerve Growth Factor
+
+355
+00:25:07,240 --> 00:25:11,920
+طبعا تشير إلى أعضاء أكسونا السيورية والتقرير بين
+
+356
+00:25:11,920 --> 00:25:17,300
+موقع أكسونا الدمج والأفكتور يعني المسافة ما بين
+
+357
+00:25:17,300 --> 00:25:20,690
+الدمج اللي صارو مابين ال organ و هى اللى هتكون
+
+358
+00:25:20,690 --> 00:25:24,510
+هيضحى هنشوفها ادنا بالصورة طبعا ال regeneration
+
+359
+00:25:24,510 --> 00:25:29,310
+عملية صعبة شوية و very slow process يعنى تقريبا فى
+
+360
+00:25:29,310 --> 00:25:36,070
+ال human growth rate واحد point يعني واحد و نص
+
+361
+00:25:36,070 --> 00:25:40,270
+يولى meter per day فى ال human رابط اكتر فى حالات
+
+362
+00:25:40,270 --> 00:25:47,500
+ال rabbit لكن اذا كانهذه العملية بيكون أسرع أو
+
+363
+00:25:47,500 --> 00:25:50,660
+بتكون بهذا الريتم إذا كان فيه عنا .. مافيش عنا
+
+364
+00:25:50,660 --> 00:25:53,960
+infection، no infection و partially cut of the
+
+365
+00:25:53,960 --> 00:25:58,140
+axon مش complete cut هذا يعني أنه لنوري الملمة is
+
+366
+00:25:58,140 --> 00:26:01,740
+intact فregeneration start in the nerve cell by
+
+367
+00:26:01,740 --> 00:26:05,900
+resuming its normal shape and content طبعا لنوري
+
+368
+00:26:05,900 --> 00:26:10,740
+الفيبرل ال axons بالsprouts of the central stem
+
+369
+00:26:10,740 --> 00:26:18,220
+will grow تصير عنا entirethe entire the neurolimb
+
+370
+00:26:18,220 --> 00:26:23,080
+tube and the extent to the distal cut end of the
+
+371
+00:26:23,080 --> 00:26:26,860
+nerve هلقيت هنشوف هذا بالصور أكتر نشوف الصور الرقم
+
+372
+00:26:26,860 --> 00:26:30,200
+واحد صار في عندنا ال trauma على الأكسن لكن ال
+
+373
+00:26:30,200 --> 00:26:35,520
+healing shape لسه مازال موجود وفي عندنا مسافة بين
+
+374
+00:26:35,520 --> 00:26:39,580
+ال muscle أو ال skeletal muscle فلاقش اللي بتصير
+
+375
+00:26:39,580 --> 00:26:43,780
+المرحلة التانية انه بتصير ال end اللي موجودة عندنا
+
+376
+00:26:44,100 --> 00:26:48,960
+الـ end of the axon بتصير swollen و بتصير كده
+
+377
+00:26:48,960 --> 00:26:52,840
+متورمة زي أي حالة من ال inflammation بتصير وما
+
+378
+00:26:52,840 --> 00:26:56,560
+بعدها هنا إيش بيصير فيه؟ بيصير فيه degeneration
+
+379
+00:26:56,560 --> 00:27:03,430
+بعد هيك للمور و للمصيدعن طريق تجارب التجارب من
+
+380
+00:27:03,430 --> 00:27:06,850
+خلال تجارب تجارب ممتازة من خلال تجارب ممتازة من
+
+381
+00:27:06,850 --> 00:27:08,410
+خلال تجارب ممتازة من خلال تجارب ممتازة من خلال
+
+382
+00:27:08,410 --> 00:27:09,170
+تجارب ممتازة من خلال تجارب ممتازة من خلال تجارب
+
+383
+00:27:09,170 --> 00:27:09,750
+ممتازة من خلال تجارب ممتازة من خلال تجارب ممتازة
+
+384
+00:27:09,750 --> 00:27:13,530
+تجارب ممتازة من خلال تجارب ممتازة من خلال تجارب
+
+385
+00:27:13,530 --> 00:27:25,630
+ممتازة من خلال تجارب ممتازة من خلال تجارب ممتاز
+
+386
+00:27:29,740 --> 00:27:33,700
+باسم الـ Neuroglia هي عبارة عن الـ connective
+
+387
+00:27:33,700 --> 00:27:37,740
+tissue في الـ central nervous system طبعا بدل ال
+
+388
+00:27:37,740 --> 00:27:41,360
+connective tissue فيه حاجة اسمها Neuroglia الـ
+
+389
+00:27:41,360 --> 00:27:46,720
+Neuroglia عبارة عن سلز موجودة supporting tissue أو
+
+390
+00:27:46,720 --> 00:27:51,340
+supporting tissue مش سلز between the neuron of the
+
+391
+00:27:51,340 --> 00:27:55,460
+central nervous system طبعا إلها أسماء شوية صعبة
+
+392
+00:27:55,460 --> 00:27:56,000
+زي ال
+
+393
+00:27:59,420 --> 00:28:09,020
+و Astrocytes و الابن ديما ال cells طبعا
+
+394
+00:28:09,020 --> 00:28:13,700
+هنا صورة أوضح بتوضح كيف بتصير عملية ال support
+
+395
+00:28:13,700 --> 00:28:17,260
+اللي موجودة و رابط ال axons مع بعض عن طريق ال
+
+396
+00:28:17,260 --> 00:28:23,040
+Oligodendrocytes اللي هي هذه و كيف ال Astrocytes
+
+397
+00:28:23,040 --> 00:28:27,140
+هنا بتساعد على التماسك
+
+398
+00:28:28,440 --> 00:28:32,600
+النيرونات مع بعضها طبعا مظيفتها تعملي support
+
+399
+00:28:32,600 --> 00:28:36,440
+similar to a function of connective tissue بتكون
+
+400
+00:28:36,440 --> 00:28:40,120
+لميالين شيطس around the axon وهو عبارة عن
+
+401
+00:28:40,120 --> 00:28:44,360
+insulators بتعمل عملية عزل بين ال نيرونات و
+
+402
+00:28:44,360 --> 00:28:49,360
+nutritive بتغذيها بتعمل defense against
+
+403
+00:28:49,360 --> 00:28:53,620
+inflammation وبتساعد في عملية ال regeneration وهذه
+
+404
+00:28:53,620 --> 00:28:59,230
+والمهمة السابعة انها بتعمل secretion ل CSFكماني
+
+405
+00:28:59,230 --> 00:29:02,730
+flow، هيك بيكون احنا نهينا محاضرتنا لليوم عن ال
+
+406
+00:29:02,730 --> 00:29:08,990
+nervous system و اتعرفنا عن ال cells كيف ال neuron
+
+407
+00:29:08,990 --> 00:29:13,350
+اشت مكوناته انه بتتكون من ال cell body و ال neuron
+
+408
+00:29:13,350 --> 00:29:18,070
+و ال axon و ال dendrites و قولنا ان وظيفة ال axon
+
+409
+00:29:18,070 --> 00:29:22,490
+convey يعني pure cellال .. ال impulse و ال
+
+410
+00:29:22,490 --> 00:29:25,190
+dendrites هو اللي بيستقبلها و قولنا ان ال central
+
+411
+00:29:25,190 --> 00:29:28,530
+nervous system بتكون من ال .. ال nervous system
+
+412
+00:29:28,530 --> 00:29:31,090
+بتكون من ال central nervous system on peripheral
+
+413
+00:29:31,090 --> 00:29:35,270
+nervous system و كمان اتعرفنا على أنواع ال nerves،
+
+414
+00:29:35,270 --> 00:29:38,410
+في عندنا sensory، في عندنا motor و في عندنا mixed
+
+415
+00:29:38,410 --> 00:29:42,660
+.. mixed nerveواتكلمنا عن انه في عندنا ال somatic
+
+416
+00:29:42,660 --> 00:29:46,080
+nervous system وفي ال autonomic nervous system
+
+417
+00:29:46,080 --> 00:29:50,080
+اللي هو الجهاز الإرادى واللا إرادى وذلك ان شاء
+
+418
+00:29:50,080 --> 00:29:53,000
+الله ننتقل في محاضرة جاية لجزء التانى من ال
+
+419
+00:29:53,000 --> 00:29:56,080
+nervous system واتاكم عافية نراكوا ان شاء الله في
+
+420
+00:29:56,080 --> 00:29:56,840
+الأسبوع المقبل
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..c4ef4eaef6139d5110f39334ca6d94c659157e6d
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8_raw.json
@@ -0,0 +1 @@
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by fatty layer اسمه الميالينشيت وهو وظيفته to conduct nerve impulse away from the body of the neuron", "tokens": [10721, 1829, 8592, 22807, 39894, 30544, 9154, 2167, 1399, 24360, 490, 264, 6360, 266, 801, 970, 4724, 1829, 3224, 4724, 28259, 10632, 4724, 1829, 9566, 1211, 3615, 9154, 2423, 2815, 1772, 39894, 30544, 30767, 1829, 18863, 1863, 4587, 46740, 2171, 5343, 538, 24898, 4583, 24525, 2304, 3224, 9673, 1829, 6027, 9957, 8592, 36081, 37037, 2407, 4032, 19913, 33911, 47395, 281, 6018, 16355, 26857, 1314, 490, 264, 1772, 295, 264, 34090], "avg_logprob": -0.341549297453652, "compression_ratio": 1.375586854460094, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 1073.03, "end": 1074.03, "word": "أيش؟", "probability": 0.6796455383300781}, {"start": 1074.03, "end": 1074.47, "word": " بتكون", "probability": 0.89501953125}, {"start": 1074.47, "end": 1074.79, "word": " من", "probability": 0.99169921875}, {"start": 1074.79, "end": 1075.41, "word": " single", "probability": 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"probability": 0.9580078125}, {"start": 1771.81, "end": 1772.31, "word": " system", "probability": 0.9765625}, {"start": 1772.31, "end": 1772.47, "word": " و", "probability": 0.9833984375}, {"start": 1772.47, "end": 1772.75, "word": " كمان", "probability": 0.9606119791666666}, {"start": 1772.75, "end": 1773.31, "word": " اتعرفنا", "probability": 0.94736328125}, {"start": 1773.31, "end": 1773.51, "word": " على", "probability": 0.90771484375}, {"start": 1773.51, "end": 1774.43, "word": " أنواع", "probability": 0.9363606770833334}, {"start": 1774.43, "end": 1774.97, "word": " ال", "probability": 0.9091796875}, {"start": 1774.97, "end": 1775.27, "word": " nerves،", "probability": 0.51953125}, {"start": 1775.27, "end": 1775.37, "word": " في", "probability": 0.82080078125}, {"start": 1775.37, "end": 1775.61, "word": " عندنا", "probability": 0.926513671875}, {"start": 1775.61, "end": 1776.23, "word": " sensory،", "probability": 0.833740234375}, {"start": 1776.23, "end": 1776.37, "word": " في", "probability": 0.98046875}, {"start": 1776.37, "end": 1776.69, "word": " عندنا", "probability": 0.985595703125}, {"start": 1776.69, "end": 1777.11, "word": " motor", "probability": 0.9833984375}, {"start": 1777.11, "end": 1777.35, "word": " و", "probability": 0.89453125}, {"start": 1777.35, "end": 1777.59, "word": " في", "probability": 0.93798828125}, {"start": 1777.59, "end": 1778.03, "word": " عندنا", "probability": 0.9853515625}, {"start": 1778.03, "end": 1778.41, "word": " mixed", "probability": 0.54443359375}, {"start": 1778.41, "end": 1778.69, "word": " ..", "probability": 0.91943359375}, {"start": 1778.69, "end": 1779.03, "word": " mixed", "probability": 0.88134765625}, {"start": 1779.03, "end": 1779.49, "word": " nerve", "probability": 0.7548828125}], "temperature": 1.0}, {"id": 76, "seek": 179684, "start": 1779.7, "end": 1796.84, "text": "واتكلمنا عن انه في عندنا ال somatic nervous system وفي ال autonomic nervous system اللي هو الجهاز الإرادى واللا إرادى وذلك ان شاء الله 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{"start": 1780.86, "end": 1781.26, "word": " انه", "probability": 0.40625}, {"start": 1781.26, "end": 1781.4, "word": " في", "probability": 0.83447265625}, {"start": 1781.4, "end": 1781.86, "word": " عندنا", "probability": 0.885986328125}, {"start": 1781.86, "end": 1782.06, "word": " ال", "probability": 0.77099609375}, {"start": 1782.06, "end": 1782.66, "word": " somatic", "probability": 0.738525390625}, {"start": 1782.66, "end": 1783.3, "word": " nervous", "probability": 0.87158203125}, {"start": 1783.3, "end": 1784.14, "word": " system", "probability": 0.9755859375}, {"start": 1784.14, "end": 1784.5, "word": " وفي", "probability": 0.85986328125}, {"start": 1784.5, "end": 1784.62, "word": " ال", "probability": 0.93798828125}, {"start": 1784.62, "end": 1785.18, "word": " autonomic", "probability": 0.7259521484375}, {"start": 1785.18, "end": 1785.5, "word": " nervous", "probability": 0.9462890625}, {"start": 1785.5, "end": 1786.08, "word": " system", "probability": 0.9755859375}, 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diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..f20e0c0d7cc281fae976ef9d8aa7510d132e4f70
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/1RQgKCwf1-8_raw.srt
@@ -0,0 +1,1684 @@
+1
+00:00:05,150 --> 00:00:07,690
+بسم الله الرحمن الرحيم محاضرتنا اليوم عن ال
+
+2
+00:00:07,690 --> 00:00:10,670
+nervous system و مكونات ال nervous system و نشوف
+
+3
+00:00:10,670 --> 00:00:15,970
+الخلية المكونة ل nervous system و تقسيماته طبعا
+
+4
+00:00:15,970 --> 00:00:19,410
+احنا معروف ان ال nervous system هو و ال endocrine
+
+5
+00:00:19,410 --> 00:00:23,980
+system هم اللي بنظموا عملية ال ..في وظائف الجسم
+
+6
+00:00:23,980 --> 00:00:28,240
+كلها وبنعرف أن الجسم أول ما بيتعرض لأي insult أو
+
+7
+00:00:28,240 --> 00:00:32,740
+بتعرض لخوف أو بتعرض لأدب بيكون الأسرع إشي في
+
+8
+00:00:32,740 --> 00:00:35,600
+التصرف هو ال nervous system ويا ليه طبعا ال
+
+9
+00:00:35,600 --> 00:00:38,540
+endocrine system اللي بيعمل بيحافظ على ال
+
+10
+00:00:38,540 --> 00:00:43,900
+hemostasis تبع الجسم يبقى هنتعرف على مكونات ال
+
+11
+00:00:43,900 --> 00:00:47,150
+nervous system هو في عندنا نوعينمن ال nervous
+
+12
+00:00:47,150 --> 00:00:49,430
+system في عندنا ال central nervous system و عندنا
+
+13
+00:00:49,430 --> 00:00:53,790
+ال peripheral nervous system ال central nervous
+
+14
+00:00:53,790 --> 00:00:56,670
+system هو عبارة عن ال brain and spinal cord و ال
+
+15
+00:00:56,670 --> 00:00:59,590
+peripheral nervous system هو عبارة عن ال nerves
+
+16
+00:00:59,590 --> 00:01:03,930
+اللى بتطلع من ال spinal cord أو من ال brain إلى
+
+17
+00:01:03,930 --> 00:01:09,200
+أجزاء الجسم كلهاطبعا ايش ال function احنا بنعرف
+
+18
+00:01:09,200 --> 00:01:13,000
+انه انا ال central nervous system بيكون في عندي
+
+19
+00:01:13,000 --> 00:01:16,940
+الو two functions اول حاجة ال sensory و في ..
+
+20
+00:01:16,940 --> 00:01:20,360
+three functions sorry ال sensory function و ال
+
+21
+00:01:20,360 --> 00:01:23,600
+motor function و ال integration function طبعا كتير
+
+22
+00:01:23,600 --> 00:01:27,500
+مهم ال link بين هدولة التلاتة functions لإنه إذا
+
+23
+00:01:27,500 --> 00:01:31,320
+كنا بنحس مابنقدرش نتصرف فطبعا بيصير في عندنا مشكلة
+
+24
+00:01:31,320 --> 00:01:35,020
+إذا كنا مافيش عندنا إحساس فهذه مشكلة طبعا أكبر لإن
+
+25
+00:01:35,020 --> 00:01:38,900
+ممكن واحد يتعرضلمخاطر هلقيت اذا انا حاسة انه انا
+
+26
+00:01:38,900 --> 00:01:42,700
+حط ايدي علي إيش سخن و هذا و حاسة ان السخن انا مش
+
+27
+00:01:42,700 --> 00:01:46,520
+قادرة ارفع ايدي عنها فهذه هتأدي الى الحرق تمام؟
+
+28
+00:01:46,520 --> 00:01:51,360
+لكن كمان لو انا كنتأنا عندي حركة كويسة لكن فيش
+
+29
+00:01:51,360 --> 00:01:54,320
+عندي إحساس فانا إيدي موجودة على إشر السخن على
+
+30
+00:01:54,320 --> 00:01:57,560
+دفاية أو على بوداكاز أو على تنجرة فانا هنحرقه مش
+
+31
+00:01:57,560 --> 00:02:02,300
+هتوصلي الإشارة للدماغ تقولني إن في عندي مشكلة
+
+32
+00:02:02,300 --> 00:02:07,020
+فهتأدي لحرق ال integration فانا ممكن أحط إيدي على
+
+33
+00:02:07,020 --> 00:02:10,600
+إشر السخن لكن مايوصل التفسير هذا للدماغ اللي على
+
+34
+00:02:10,600 --> 00:02:15,250
+أساسه هيصير التصرف بعد هيكو قوله ارفع ايدك عن ال
+
+35
+00:02:15,250 --> 00:02:20,030
+.. ال .. الدفاية او عن ال .. قشر السخن فيبقى هدول
+
+36
+00:02:20,030 --> 00:02:23,070
+التلاتة components لازم تكون عشان انا اخد good
+
+37
+00:02:23,070 --> 00:02:25,790
+function لازم يكونوا عندى ال sensory و ال motor و
+
+38
+00:02:25,790 --> 00:02:29,530
+ال integrative function intactإيش هي ال sensory؟
+
+39
+00:02:29,530 --> 00:02:32,330
+فهي عبارة عن sensory receptors gathering
+
+40
+00:02:32,330 --> 00:02:36,670
+information، ال information هذه بتروح وين؟ أنا
+
+41
+00:02:36,670 --> 00:02:40,230
+باخد، طبعا في عندي ال special senses مثلا زي
+
+42
+00:02:40,230 --> 00:02:43,590
+البصر، أنا ماشية في الطريق، في قدامي حفرة، في
+
+43
+00:02:43,590 --> 00:02:47,170
+قدامي درج، فأنا بيعطيني order، بوصل ل .. بروح
+
+44
+00:02:47,170 --> 00:02:50,150
+للدماغ، أول إشي الإشارة بتروح لدماغ، بتقول إن في
+
+45
+00:02:50,150 --> 00:02:54,030
+هنا عطبة، خلّي بالك لما تنزلي أحسنتتوقعه فبيعطي
+
+46
+00:02:54,030 --> 00:02:57,890
+إشارة لأول إشي بتروح إشارة عندك بتعمل
+
+47
+00:02:57,890 --> 00:03:00,810
+interpretation بتعمل interpretation بتقوله هنا في
+
+48
+00:03:00,810 --> 00:03:04,290
+عطبة هنا في حفرة ابعدي عنها فبيجي ال order ل
+
+49
+00:03:04,290 --> 00:03:07,830
+skeletal system عشان هو يتسرى فيبقى sensory
+
+50
+00:03:07,830 --> 00:03:11,190
+receptors gathering information بتاخد ال
+
+51
+00:03:11,190 --> 00:03:16,850
+information من البيئة المحيطة بترسلها لمين ل ال
+
+52
+00:03:16,850 --> 00:03:20,990
+central nervous system أو ل ال brainفي بعض الحركات
+
+53
+00:03:20,990 --> 00:03:23,970
+بتكون reflex يعني مابتوصل لليبران يعني انا لو حطت
+
+54
+00:03:23,970 --> 00:03:26,650
+ايدي على مسكة فاتحت ال microwave بدي اخد الصحن
+
+55
+00:03:26,650 --> 00:03:30,450
+لقيته سخن بارميه لأنه ماوصلش هذه reflex على طول
+
+56
+00:03:30,450 --> 00:03:34,730
+انا حسيت انه سخن automatic رميته و حاميت نفسي فهذه
+
+57
+00:03:34,730 --> 00:03:38,090
+في بعض الإشارات دعست على الدبوس دعست على الدبوس
+
+58
+00:03:38,090 --> 00:03:42,830
+هذا لسه أعلى من وصل الإشارة لدماغ منكون الدبوس خرق
+
+59
+00:03:42,830 --> 00:03:46,250
+رجلنا لأ هو على طول فورا انت بتروح ترفع احنا بنقول
+
+60
+00:03:46,250 --> 00:03:51,110
+بنرفع رجلنا عن الدبوس هذه في حالةإنه لو صار الأمر
+
+61
+00:03:51,110 --> 00:03:53,810
+preference أما ال integration فهي ال sensor و ال
+
+62
+00:03:53,810 --> 00:03:57,310
+information used to create ال sensation و كمان ال
+
+63
+00:03:57,310 --> 00:04:01,110
+memory و ال thoughts و ال decisions فهذه كلها أمور
+
+64
+00:04:01,110 --> 00:04:07,990
+بتحتاج ل interpretation أو ترجمة فهي integrated
+
+65
+00:04:07,990 --> 00:04:14,590
+functionأما ال motor function فبتكلم عن ال action
+
+66
+00:04:14,590 --> 00:04:18,730
+أنا بدي أبعد هنا لإنه في هنا حفرة، أنا بدي أرفع
+
+67
+00:04:18,730 --> 00:04:22,070
+إيدي لإنه هذا الاشي سخن، أنا والله بفطلع إنها
+
+68
+00:04:22,070 --> 00:04:27,150
+والله في سيارة جادة شقطع الشارع، تمام؟ فهذه إبراعا
+
+69
+00:04:28,010 --> 00:04:31,970
+عملية ال integration ما بين ال sensory و ما بين ال
+
+70
+00:04:31,970 --> 00:04:37,070
+.. ال motor و بعدين هي اللي بتعطينا التفسير لظواهر
+
+71
+00:04:37,070 --> 00:04:41,230
+اللي حولنا أما ال motor لأ ال motor فهي بتعطيني
+
+72
+00:04:41,230 --> 00:04:45,410
+effort بتدوي السير على طول انا ال impulse هذه
+
+73
+00:04:45,410 --> 00:04:50,170
+بتقول ارفع ايدك ميل على اليمين ميل على اليسار ابعد
+
+74
+00:04:50,170 --> 00:04:54,430
+واقفطبعا ال organization of the nervous system
+
+75
+00:04:54,430 --> 00:04:59,150
+detect .. ال organized to detect the changes in
+
+76
+00:04:59,150 --> 00:05:02,630
+the internal and external environment يعني ال
+
+77
+00:05:02,630 --> 00:05:06,550
+nervous system بس ما بتنظر بيعطيني مؤشرات على
+
+78
+00:05:06,550 --> 00:05:10,430
+البيئة اللي حواليا أو إشارات لأ كمان internally
+
+79
+00:05:10,430 --> 00:05:13,910
+إيش بيصير و لأ أنا حاسس حالي سخن، أنا حاسس حالي
+
+80
+00:05:13,910 --> 00:05:17,930
+شوبان، أنا حاسس حالي جوعان، أنا حاسس حالي أتشان
+
+81
+00:05:17,930 --> 00:05:22,490
+كمانand initiate appropriate response طب الله انا
+
+82
+00:05:22,490 --> 00:05:26,470
+جعانى بفضل روح اكل انا عشان بدي روح اشرب انا والله
+
+83
+00:05:26,470 --> 00:05:30,890
+حاسس حالة حران بدي اروح او افقد دم روحها او بدي
+
+84
+00:05:30,890 --> 00:05:35,990
+اغير ملابسي او بدي اخد دوش او whateverطبعا ال sub
+
+85
+00:05:35,990 --> 00:05:40,050
+divisions لل system في عندنا او ال central nervous
+
+86
+00:05:40,050 --> 00:05:43,150
+system أو في عندنا ال peripheral nervous system ال
+
+87
+00:05:43,150 --> 00:05:45,630
+central nervous system عبارة عن ال brain and
+
+88
+00:05:45,630 --> 00:05:52,150
+spinal cord طبعا هو إيش وظيفته integratesensor
+
+89
+00:05:52,150 --> 00:05:55,650
+information evaluate it وكمان بيعطينا ال response
+
+90
+00:05:55,650 --> 00:06:01,570
+او outgoing response بالظبط زي ما انا قلت من الاول
+
+91
+00:06:01,570 --> 00:06:05,230
+انا حسيت هنا هذا اشي سخن راح لدماغ اللي والله هنا
+
+92
+00:06:05,230 --> 00:06:08,690
+في حاجة سخنة ابعدي عنها فبيجيني ال order اني انا
+
+93
+00:06:08,690 --> 00:06:12,430
+اشيل ايدي عنهاطبعا أما ال peripheral nervous
+
+94
+00:06:12,430 --> 00:06:15,890
+system فهو بيستقبل من ال brain و بيستقبل من ال
+
+95
+00:06:15,890 --> 00:06:19,870
+spinal cord ال cranial nerve بتاخد الأمر لأنها هي
+
+96
+00:06:19,870 --> 00:06:23,950
+في منطقتنا قبل ال spinal cord فبتطلع من ال crania
+
+97
+00:06:23,950 --> 00:06:27,990
+نفسها فبتسمى بتاخد من ال brain ل ال periphery ها
+
+98
+00:06:27,990 --> 00:06:32,350
+دي بتغذي عضلات الفاس و ال swallowing و ال neck
+
+99
+00:06:32,350 --> 00:06:35,830
+accessory ايه مثلا؟أما الـ spinal nerve فهي بتطلع
+
+100
+00:06:35,830 --> 00:06:38,510
+من الـ spinal cord بتروح ل الـ appendicular
+
+101
+00:06:38,510 --> 00:06:41,970
+musculoskeletal system على أساس أنه تعمل ليه تعمل
+
+102
+00:06:41,970 --> 00:06:48,410
+perform ل الحركة وكمان على ال internal organs هانا
+
+103
+00:06:48,410 --> 00:06:54,130
+نبدأ بالصور الموضحة بالأشكال فعنا الصورة هذه بتوضح
+
+104
+00:06:54,130 --> 00:06:58,610
+أنه في عندنا هناالـ brain والـ spinal cord هدوء
+
+105
+00:06:58,610 --> 00:07:01,570
+الـ central nervous system وفيه إنها ال cranial
+
+106
+00:07:01,570 --> 00:07:08,570
+nerve و ال spinal nerve اللي هي بتغذي ال periphery
+
+107
+00:07:08,570 --> 00:07:11,450
+of the body
+
+108
+00:07:13,130 --> 00:07:18,170
+طبعا فيه هنا sensory divisions للبرفيرال نيرفي،
+
+109
+00:07:18,170 --> 00:07:21,250
+هنا sensory و في عندنا motor و كمان ال motor
+
+110
+00:07:21,250 --> 00:07:27,850
+بتنقسم ل somatic and autonomic nervous system ال
+
+111
+00:07:27,850 --> 00:07:31,370
+sensory طبعا بتاخد ال pick up sensory information
+
+112
+00:07:31,370 --> 00:07:36,190
+and deliver it to the central nervous system،
+
+113
+00:07:36,190 --> 00:07:42,550
+بتاخد المعلومة أو الإشارةعن طريق الجسم وبترسلها لل
+
+114
+00:07:42,550 --> 00:07:45,930
+central nervous system سواء لل spinal cord اللى
+
+115
+00:07:45,930 --> 00:07:50,390
+بيرفعها عن طريق ال elevators تبعته إلى الدماغ فى
+
+116
+00:07:50,390 --> 00:07:54,370
+أن ال motor divisions بتعطينى information عن ال
+
+117
+00:07:54,370 --> 00:07:59,670
+muscles and gland يعنى بتعطينى حالة العضلات وحالة
+
+118
+00:07:59,670 --> 00:08:05,280
+ال gland اللى موجودة فى الجسمال motor system اللي
+
+119
+00:08:05,280 --> 00:08:08,240
+بينقسم ل somatic و autonomous ال somatic هو اللي
+
+120
+00:08:08,240 --> 00:08:12,700
+بروح لل muscles system اللي بعملي الحركة يعني هو
+
+121
+00:08:12,700 --> 00:08:17,440
+اللي بقولي ابعدي روحي تعالي امسكي اشربي امسكي
+
+122
+00:08:17,440 --> 00:08:21,420
+الكباية العضلات هي اللي بتعمل هذا الشغل اما ال
+
+123
+00:08:21,420 --> 00:08:25,640
+autonomous فهوكمان اللي هو جهاز اللا إرادي بمعنى
+
+124
+00:08:25,640 --> 00:08:29,020
+إنه أنا ما بتحكم في عضلة القلب أقولها دقي وما
+
+125
+00:08:29,020 --> 00:08:32,000
+أدقيش تمام؟ ال glance أنا ما بتحكم بالإفرازات
+
+126
+00:08:32,000 --> 00:08:38,600
+تبعتها لكن في nervous system بيتحكم حقيقي فيها
+
+127
+00:08:38,600 --> 00:08:41,580
+carried information to the smooth muscle و ال
+
+128
+00:08:41,580 --> 00:08:46,120
+cardiac muscle and the glance طبعا هذا الرسم
+
+129
+00:08:46,120 --> 00:08:50,220
+التوضيحي بوضح لنا حالة الأسرار
+
+130
+00:08:53,990 --> 00:09:00,310
+أحنا أين روحنا؟ هنا، عندنا الـ brain زي ما أحنا
+
+131
+00:09:00,310 --> 00:09:05,090
+شايفين و ال spinal cord مثل عامله ال spinal nerve،
+
+132
+00:09:05,090 --> 00:09:08,510
+طبعا في عندنا ال sensory receptors هي اللي بترفع
+
+133
+00:09:08,510 --> 00:09:12,170
+لـ brain، في عندنا ال motor اللي هي ال somatic
+
+134
+00:09:12,170 --> 00:09:14,830
+اللي بتروح على ال skeletal muscle و في عندنا ال
+
+135
+00:09:14,830 --> 00:09:18,290
+anatomic اللي بتروح على السموت وال cardiac and
+
+136
+00:09:18,290 --> 00:09:24,300
+glandsالـ الـ systems according to the type of
+
+137
+00:09:24,300 --> 00:09:28,160
+organs they innervate في عندنا الـ somatic الـ
+
+138
+00:09:28,160 --> 00:09:30,920
+somatic motor و في somatic sensory طبيعي أنه
+
+139
+00:09:30,920 --> 00:09:35,480
+الجسدية أو خلال العصاب الجسدية ال somatic motor
+
+140
+00:09:35,480 --> 00:09:38,560
+division carried information to the somatic
+
+141
+00:09:38,560 --> 00:09:42,380
+effectors اللي هي ال skeletal مثلا أما ال sensory
+
+142
+00:09:42,380 --> 00:09:46,780
+divisions فهي carried feedback تأخد ال feedback من
+
+143
+00:09:46,780 --> 00:09:52,740
+العضلاتto the somatic integration
+
+144
+00:09:52,740 --> 00:09:56,560
+center of the central nervous يعني الموتر هي اللي
+
+145
+00:09:56,560 --> 00:10:02,300
+بترسل و ال sensor هي اللي بتستقبل هذا باختصار أما
+
+146
+00:10:02,300 --> 00:10:06,200
+ال atomic nervous system عبارة عن efferent
+
+147
+00:10:06,200 --> 00:10:09,810
+divisionsالـ different divisions هذه فيها الـ
+
+148
+00:10:09,810 --> 00:10:13,150
+sympathetic والبارع sympathetic وظفتها carried
+
+149
+00:10:13,150 --> 00:10:15,670
+information to the autonomic and visceral
+
+150
+00:10:15,670 --> 00:10:19,270
+effectors اللي هي smooth and cardiac muscle and
+
+151
+00:10:19,270 --> 00:10:23,350
+gland هاي ال sympathetic divisions عبارة عن اللي
+
+152
+00:10:23,350 --> 00:10:29,160
+هو ال .. يعني فلان نقول وسيلة الدفع عن الجسمعادة
+
+153
+00:10:29,160 --> 00:10:32,760
+بتعمل preparation to the body to deal with any
+
+154
+00:10:32,760 --> 00:10:37,500
+dehydrating to the internal environment يعني إذا
+
+155
+00:10:37,500 --> 00:10:40,860
+كان أي إشي بيشكل خطر فعلى طول ال sympathetic
+
+156
+00:10:40,860 --> 00:10:48,100
+system هو بيشتغل حتى تتمكن من الهروب من الخطر عادة
+
+157
+00:10:48,620 --> 00:10:51,220
+أما الـ Parasympathetic System فهذا بيشتغل في الـ
+
+158
+00:10:51,220 --> 00:10:55,000
+Rest، هذا هو مرتاح هو مرتاح الشخص قنايم اللي
+
+159
+00:10:55,000 --> 00:10:57,820
+بيشتغل coordinate the body's normal resting
+
+160
+00:10:57,820 --> 00:11:01,580
+activity الـ Visceral Sensory Divisions carried في
+
+161
+00:11:01,580 --> 00:11:04,440
+كتاب Feedback Information للـ Autonomic
+
+162
+00:11:04,440 --> 00:11:08,840
+Integrating Center of the .. يعني هنا في عندي في
+
+163
+00:11:08,840 --> 00:11:14,900
+كل الفذرة أو الـ Internal Organs فيها Sensoryالـ
+
+164
+00:11:14,900 --> 00:11:19,180
+sensory neurons هذه بترفع ليه على ال autonomous
+
+165
+00:11:19,180 --> 00:11:22,620
+nervous system من ال autonomous nervous system لال
+
+166
+00:11:22,620 --> 00:11:27,700
+brain أو لcentral nervous systemتتكلمنا عن الـ
+
+167
+00:11:27,700 --> 00:11:30,940
+afferent and efferent divisions، الـ afferent هي
+
+168
+00:11:30,940 --> 00:11:35,240
+اللي بترفع، هي عبارة incoming sensory pathways هي
+
+169
+00:11:35,240 --> 00:11:38,880
+اللي بترفع ال ways .. هي بترفع لدماج، أما ال
+
+170
+00:11:38,880 --> 00:11:41,460
+efferent فهي اللي بتعطينا العودة، يعني احنا في
+
+171
+00:11:41,460 --> 00:11:45,420
+عندنا elevator ساعد و في عندنا elevator نازل، ال
+
+172
+00:11:45,420 --> 00:11:50,180
+afferent هي المصعد اللي طالع إلى ال brain أما ال
+
+173
+00:11:50,180 --> 00:11:54,080
+efferent هي المصعد اللي نازل من ال brain إلى ال
+
+174
+00:11:54,080 --> 00:11:55,120
+motor pathways
+
+175
+00:11:58,750 --> 00:12:04,470
+طبعا ال components of somatic sensory عادة ال
+
+176
+00:12:04,470 --> 00:12:07,950
+general somatic senses زي ال touch، البان، ال
+
+177
+00:12:07,950 --> 00:12:11,010
+pressure، ال vibration، ال temperature، ال
+
+178
+00:12:11,010 --> 00:12:13,970
+proprioceptions اللي موجود في .. اللي بيعطيني حالة
+
+179
+00:12:13,970 --> 00:12:19,130
+ال .. ال jointsأما ال special senses زي ال test،
+
+180
+00:12:19,130 --> 00:12:23,090
+التدوق و ال vision، ال hearing، ال balance، ال
+
+181
+00:12:23,090 --> 00:12:27,890
+smells، هذه كلها special senses و هي ال sensory as
+
+182
+00:12:27,890 --> 00:12:28,130
+well
+
+183
+00:12:30,970 --> 00:12:34,270
+أما الـ visceral sensory component طبعا ترسمت
+
+184
+00:12:34,270 --> 00:12:38,070
+impulse nerve impulse from the blood vessels to
+
+185
+00:12:38,070 --> 00:12:42,550
+the viscera to the central nervous system يعني
+
+186
+00:12:42,550 --> 00:12:45,710
+بتاخد المعلومات من الviscera أو من blood vessels و
+
+187
+00:12:45,710 --> 00:12:49,550
+بتطلع فيها على الدماغ الvisceral sense primarily
+
+188
+00:12:49,550 --> 00:12:52,630
+include temperature و ال stretch يعني قدش بيصير في
+
+189
+00:12:52,630 --> 00:12:57,190
+stretch في الفذر قدش احنا بنقدر ان نحس اننا نعتمد
+
+190
+00:12:57,190 --> 00:13:02,460
+على كمية ال stretchاللي بتصير في ال organ أما ال
+
+191
+00:13:02,460 --> 00:13:08,660
+motor ففي عندنا طبعا ال motor somatic nervous
+
+192
+00:13:08,660 --> 00:13:12,260
+system هو call back to impulse طبعا مدام motor
+
+193
+00:13:12,260 --> 00:13:16,000
+يبقى بدوره على ال skeletal muscle known as
+
+194
+00:13:16,000 --> 00:13:18,680
+voluntary nervous system وفي الautonomic اللي هو
+
+195
+00:13:18,680 --> 00:13:21,660
+ال involuntary احنا ما بنتحكم في ال internal
+
+196
+00:13:21,660 --> 00:13:25,100
+organs تبعتنا في ال internal organs ريكوليات ال
+
+197
+00:13:25,100 --> 00:13:29,080
+smooth muscle و ال cardiac muscle و ال glandطبعا
+
+198
+00:13:29,080 --> 00:13:32,440
+انربيات ال internal organs كلها رجليات ال smooth
+
+199
+00:13:32,440 --> 00:13:35,360
+muscle و رجليات ال cardiac muscle و ال glands
+
+200
+00:13:35,360 --> 00:13:39,560
+known as involuntary nervous system يعني في عندنا
+
+201
+00:13:39,560 --> 00:13:42,800
+voluntary nervous system و في عندنا involuntary أو
+
+202
+00:13:42,800 --> 00:13:45,900
+somatic nervous system اللي هو ال somatic ال
+
+203
+00:13:45,900 --> 00:13:49,280
+voluntary و ال autonomous هو ال involuntary
+
+204
+00:13:49,280 --> 00:13:52,500
+nervous system لو احنا قرأناها في كتاب تاني او
+
+205
+00:13:52,500 --> 00:13:55,580
+سمعنا عنها فبنعرف ان ال somatic هو ال voluntary و
+
+206
+00:13:55,580 --> 00:13:58,740
+ال autonomous هو ال involuntaryبطريقة دراسة توضيحي
+
+207
+00:13:58,740 --> 00:14:02,620
+للـ function لل organization نلاقي أن ال nervous
+
+208
+00:14:02,620 --> 00:14:06,360
+system ينقسم ل ال sensory affluent divisions هو
+
+209
+00:14:06,360 --> 00:14:10,340
+بيبعت ال information على ال central nervous system
+
+210
+00:14:12,140 --> 00:14:16,140
+وكمان ال motor هو اللي بيرسل من ال central nervous
+
+211
+00:14:16,140 --> 00:14:20,920
+system ل ال periphery ال sensory afferent division
+
+212
+00:14:20,920 --> 00:14:24,180
+بتقسم لل somatic و ال visceral ال somatic بروح على
+
+213
+00:14:24,180 --> 00:14:27,280
+ال musculoskeletal و ال special sense أما ال
+
+214
+00:14:27,280 --> 00:14:30,720
+visceral فهو ال information بيقودها من الفذرة أو
+
+215
+00:14:30,720 --> 00:14:36,280
+الأحشاقانجاز التعبير في بالعربي أما ال motor فبروح
+
+216
+00:14:36,280 --> 00:14:39,140
+ال somatic motor autonomic وقلنا voluntary and
+
+217
+00:14:39,140 --> 00:14:42,440
+involuntary ال voluntary بتحكم بال musculoskeletal
+
+218
+00:14:42,440 --> 00:14:46,140
+أما ال involuntary في ال cardiac و ال smooth and
+
+219
+00:14:46,140 --> 00:14:51,450
+declined muscleروح لـ nerve cells اللي هو الوحدة
+
+220
+00:14:51,450 --> 00:14:55,290
+المكوّنة لـ nervous system هي عبارة عن ال nerve
+
+221
+00:14:55,290 --> 00:14:59,190
+cell two different type of nerve cells في عندنا ال
+
+222
+00:14:59,190 --> 00:15:03,030
+neurons و في عندنا ال glial cells ال neurons هي ال
+
+223
+00:15:03,030 --> 00:15:07,170
+excitable وهي اللي بتعمل transmission ل ال impulse
+
+224
+00:15:07,170 --> 00:15:10,590
+اللي بتساعد على حركة ال impulse يعني هي الكهربا
+
+225
+00:15:10,790 --> 00:15:15,510
+خلّيني أقول هي السلك الكهربائي اللي بيوصل الكهربا
+
+226
+00:15:15,510 --> 00:15:18,230
+من الـ central nervous system للـ peripheral
+
+227
+00:15:18,230 --> 00:15:21,710
+nervous system والعزيزي أما الـ glial cell فهي non
+
+228
+00:15:21,710 --> 00:15:25,690
+excitable يعني ممنوع بتعطيني إشارات كهربائية لكن
+
+229
+00:15:25,690 --> 00:15:29,610
+بتعطيني support و protection زي وظيفة اللي هي ال
+
+230
+00:15:29,610 --> 00:15:32,850
+connective tissue بس لأن ال nervous system بيحتوي
+
+231
+00:15:32,850 --> 00:15:36,690
+على connective tissue فهو بيحتوي على glial cells
+
+232
+00:15:36,690 --> 00:15:40,400
+اللي بتعطيني support و protectionطب ايش ترتيبة
+
+233
+00:15:40,400 --> 00:15:43,700
+لنيرون؟ اي نيرون موجود في عيننا الـ Structural
+
+234
+00:15:43,700 --> 00:15:46,520
+انفاق هو التعريف هو الـ Structural Unfunctional
+
+235
+00:15:46,520 --> 00:15:51,280
+Unit للنرفسيستيم هو بتكون من نيرسل و two processes
+
+236
+00:15:51,280 --> 00:15:57,040
+ال process الأول اللي هو ال Dendrites اللي هو
+
+237
+00:15:57,040 --> 00:16:03,020
+بيستقتل الإشارة و ال Axon اللي هو بيرسل الإشارة
+
+238
+00:16:03,020 --> 00:16:05,180
+طيب
+
+239
+00:16:06,110 --> 00:16:12,070
+إيش ال characteristics تبعت ال neuron هو highly
+
+240
+00:16:12,070 --> 00:16:18,590
+metabolic rates يعني ال ID عنده عالي لكن هو
+
+241
+00:16:18,590 --> 00:16:23,530
+extreme longevity بيعيش فترات قوية وكمان non
+
+242
+00:16:23,530 --> 00:16:28,660
+-metathetic يعني بيصير في انقسامات ال neuronيعني
+
+243
+00:16:28,660 --> 00:16:30,740
+عمنا نعرف إن الخلية بيصير فيها انقسام، الـ neurons
+
+244
+00:16:30,740 --> 00:16:34,440
+لأ ما بيصير فيها انقسام، أه؟ طيب الـ neuron comes
+
+245
+00:16:34,440 --> 00:16:40,040
+in all shapes and sizes share certain basic
+
+246
+00:16:40,040 --> 00:16:43,320
+structure feature اللي هي ال cell body و الaxon
+
+247
+00:16:43,320 --> 00:16:47,020
+and dendritic وهنا زي ما إحنا شايفين ال cell body
+
+248
+00:16:47,020 --> 00:16:50,780
+أي cell body فيها أو بيسموها الـ soma فيها ال
+
+249
+00:16:50,780 --> 00:16:55,260
+nucleusالـ Dendritis هي التشعبات اللي احنا
+
+250
+00:16:55,260 --> 00:17:00,600
+شايفينها هنا ثم الـ Axon فهي الـ لونجة اللي قد
+
+251
+00:17:00,600 --> 00:17:05,520
+حنشوفها الـ process السلبة
+
+252
+00:17:05,520 --> 00:17:14,040
+دي هي الـ center لـ neurons control center طبعا
+
+253
+00:17:14,040 --> 00:17:19,720
+responsible for تستقبل receiving integrating and
+
+254
+00:17:19,720 --> 00:17:25,910
+sending nerve impulseأما تركيبها فهي عبارة عن
+
+255
+00:17:25,910 --> 00:17:31,270
+plasma membrane وفيه cytoplans طبعا أي خلية فيها
+
+256
+00:17:31,270 --> 00:17:35,890
+plasma membrane وcytoplans فيها nucleus with
+
+257
+00:17:35,890 --> 00:17:41,190
+prominent nucleus في عندنا ال chromatophilic
+
+258
+00:17:41,190 --> 00:17:47,110
+substances وفي عندنا every ribosomes تركيب أي خلية
+
+259
+00:17:47,110 --> 00:17:50,030
+أما ال axons فهو عبارة عن
+
+260
+00:17:53,030 --> 00:17:57,310
+أيش؟ بتكون من single process extending from the
+
+261
+00:17:57,310 --> 00:18:06,850
+axon helix بيه بداية بيطلع من ال cell body بتكون
+
+262
+00:18:06,850 --> 00:18:11,670
+زي العنق له sometimes covered by fatty layer اسمه
+
+263
+00:18:11,670 --> 00:18:15,570
+الميالينشيت وهو وظيفته to conduct nerve impulse
+
+264
+00:18:15,570 --> 00:18:21,240
+away from the body of the neuronوهذا شكل ال axon
+
+265
+00:18:21,240 --> 00:18:26,380
+هو long process زي ما احنا شايفينه وهنا احنا زي ما
+
+266
+00:18:26,380 --> 00:18:31,840
+احنا شايفينها ال axon هايلوك اللي هي بداية ال axon
+
+267
+00:18:31,840 --> 00:18:37,060
+وبعدين في عندنا الشيوت وفي عندنا ال node of
+
+268
+00:18:37,060 --> 00:18:41,160
+ramfiers وضيفته
+
+269
+00:18:41,160 --> 00:18:46,570
+انه send the impulseأما الـ Dendrite فهو المستقبل،
+
+270
+00:18:46,570 --> 00:18:50,150
+each neuron has one or more يعني ممكن يكون دندريت
+
+271
+00:18:50,150 --> 00:18:54,850
+واحد أو متشعب with which branch from the cell body
+
+272
+00:18:54,850 --> 00:18:58,990
+conduct nerve signal towards the cell body of the
+
+273
+00:18:58,990 --> 00:19:04,670
+neuron طبعا الـ distal end of dendritis or of
+
+274
+00:19:04,670 --> 00:19:08,050
+sensory neurons هي الـ Receptors لأن هو اللي
+
+275
+00:19:08,050 --> 00:19:12,430
+بيستقبل ال impulse طبعا
+
+276
+00:19:12,430 --> 00:19:16,580
+الوضع مختلفبتختلف في ال structure تبعها أو ال
+
+277
+00:19:16,580 --> 00:19:20,540
+classification حسب ال structure and ال ال function
+
+278
+00:19:20,540 --> 00:19:25,540
+ال structural classification number of processes
+
+279
+00:19:25,540 --> 00:19:30,060
+extended from فممكن unipolar او bipolar او
+
+280
+00:19:30,060 --> 00:19:35,420
+multipolar الرسم هنا بيوضح اكتر ال unipolar في one
+
+281
+00:19:35,420 --> 00:19:40,050
+process andزي ال ganglia يعني في عندنا process
+
+282
+00:19:40,050 --> 00:19:44,930
+واحد زي ما احنا شايفينه هنا بيطلع فوق و تحت أما ال
+
+283
+00:19:44,930 --> 00:19:50,910
+bipolar فبياخد فوق و تحت فيه إتجاهين زي ال ear و
+
+284
+00:19:50,910 --> 00:19:54,290
+ال nose ال neurons اللي بتكون في ال ear و ال nose
+
+285
+00:19:54,290 --> 00:19:57,350
+و ال eye أما ال multipolar فهو ال neurons of the
+
+286
+00:19:57,350 --> 00:20:01,670
+central has many processes of the central most
+
+287
+00:20:01,670 --> 00:20:06,650
+neurons of the central nervous systemطبعا هذا بعد
+
+288
+00:20:06,650 --> 00:20:11,850
+التوضيح الصورة بتوضح بعض ال neurons ل ال
+
+289
+00:20:11,850 --> 00:20:17,630
+peripheral nervous system كيف في عندنا أحيانا في
+
+290
+00:20:17,630 --> 00:20:21,790
+حاجة اسمها inter neurons و في عندنا sensor neurons
+
+291
+00:20:21,790 --> 00:20:26,290
+و في عندنا motor neurons ال sensory هي ال afferent
+
+292
+00:20:26,290 --> 00:20:31,210
+اللي بترسل الإشارة إلى ال central nervous system و
+
+293
+00:20:31,210 --> 00:20:36,150
+معظمها unipolarوبعضها من الـ bipolar أما الـ inter
+
+294
+00:20:36,150 --> 00:20:39,370
+neurons فعادة بتكون multi polar لأنها linked
+
+295
+00:20:39,370 --> 00:20:43,890
+neurons together أما ال motor neurons فهي multi
+
+296
+00:20:43,890 --> 00:20:47,030
+polar و carry impulse away from the central
+
+297
+00:20:47,030 --> 00:20:52,870
+nervous system to the effector يعني للعضلات و لل
+
+298
+00:20:52,870 --> 00:21:00,710
+other components وهذه صورة توضحية لبعض ال ..
+
+299
+00:21:06,350 --> 00:21:11,330
+الـ neurons زي الـ sensory و الموتر الموتر هتجينا
+
+300
+00:21:11,330 --> 00:21:15,210
+الحركة هتجينا من الـ skeletal هتروح للـ skeletal
+
+301
+00:21:15,210 --> 00:21:19,510
+muscle أما الـ sensory ممكن تجينا من أي receptors
+
+302
+00:21:19,510 --> 00:21:24,190
+تانية وحتى التحم عن طريق الـ internal neuron عشان
+
+303
+00:21:24,190 --> 00:21:27,990
+ترجع الحركة عن طريق Spinal cord لو كانت reflex
+
+304
+00:21:30,600 --> 00:21:38,980
+و هذا شكل بيوضح كيف بتصير عملية ال .. ال reflex لو
+
+305
+00:21:38,980 --> 00:21:43,700
+شكنا دبوس على طول بتروح الإشارة عن طريق ال spinal
+
+306
+00:21:43,700 --> 00:21:47,020
+nerve أو على ال sensory nerve على ال spinal cord و
+
+307
+00:21:47,020 --> 00:21:53,460
+فورا بترجع على ال .. ال .. الإصبع مثلا حتى يبتعد
+
+308
+00:21:53,460 --> 00:21:54,660
+عن الدبوس
+
+309
+00:22:03,400 --> 00:22:06,900
+طبعا ال nerves هي عبارة عن organs of the
+
+310
+00:22:06,900 --> 00:22:11,440
+peripheral nervous system ال nerves عادة في عندنا
+
+311
+00:22:11,440 --> 00:22:14,740
+sensory nerves اللي هي بتاخد الإشارة convey
+
+312
+00:22:14,740 --> 00:22:17,520
+sensory information to the central nervous system
+
+313
+00:22:17,520 --> 00:22:21,380
+وعكسها على طول في عندنا ال motor nerves اللي بتعمل
+
+314
+00:22:21,380 --> 00:22:25,160
+convey لل motor impulse على ال muscle and the
+
+315
+00:22:25,160 --> 00:22:28,160
+glands وفي عندنا ال mix اللي بيكون منها sensory
+
+316
+00:22:28,160 --> 00:22:34,700
+بتكون تجمع بين sensory and motorالأكسونات تنتهي
+
+317
+00:22:34,700 --> 00:22:39,220
+عندما تتواصل مع نيرونات أخرى مثل عضو أو عضو عضو أو
+
+318
+00:22:39,220 --> 00:22:40,340
+عضو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+319
+00:22:40,340 --> 00:22:41,320
+أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+320
+00:22:41,320 --> 00:22:42,700
+أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+321
+00:22:42,700 --> 00:22:45,840
+أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+322
+00:22:45,840 --> 00:22:46,220
+أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+323
+00:22:46,220 --> 00:22:47,740
+أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو أو عضو
+
+324
+00:22:47,740 --> 00:22:56,900
+أو عضو أو عضو أو عضو أو عهلأ ده إيش ال
+
+325
+00:22:56,900 --> 00:23:00,880
+organization نفسه لل nerve أو ال .. ال .. ال
+
+326
+00:23:00,880 --> 00:23:07,260
+neuron؟ في كل neuron بي .. بيحاط في .. في عينا
+
+327
+00:23:07,260 --> 00:23:09,840
+الإبي، الموريام، راب، كل
+
+328
+00:23:12,490 --> 00:23:17,110
+أما البري انيرون فهو راب الفاسيكلز مجموعة من ال
+
+329
+00:23:17,110 --> 00:23:20,190
+nerves وفي ال endoneurons اللي هو راب ال
+
+330
+00:23:20,190 --> 00:23:23,750
+individual axon of the nerve يعني ال axon اللي
+
+331
+00:23:23,750 --> 00:23:29,260
+واحد راب ال endoneuronمجموعة من الـ axons رابست by
+
+332
+00:23:29,260 --> 00:23:34,920
+الـ perineuron أما الغشاء الخارجي اللي بيحيط كل
+
+333
+00:23:34,920 --> 00:23:39,220
+الـ neuron فبيسمى الـ epineuron هي الصورة الأكتر
+
+334
+00:23:39,220 --> 00:23:43,930
+بتوضح الـ axon نفسهوكيف محاط بالـ endoneuron
+
+335
+00:23:43,930 --> 00:23:47,970
+ومجموعة منهم .. مجموعة من الـ axons محاط
+
+336
+00:23:47,970 --> 00:23:52,970
+بالبرينيرون والنيرب نفسه محاط بالابنيرون طب عملية
+
+337
+00:23:52,970 --> 00:23:57,290
+ال rebirth كيف تصير ال mature neurons are
+
+338
+00:23:57,290 --> 00:24:00,830
+incapable of cell division طبعا مافيش division
+
+339
+00:24:00,830 --> 00:24:04,530
+عشان هيك أي damage لل nervous system بيكون
+
+340
+00:24:04,530 --> 00:24:08,380
+permanentوقتش ممكنش permanent عيدنا هنشوف ال
+
+341
+00:24:08,380 --> 00:24:11,300
+neurons have limited capacity to repair themselves
+
+342
+00:24:11,300 --> 00:24:14,280
+ال nerve fibers can be repaired إذا كان ال damage
+
+343
+00:24:14,280 --> 00:24:18,740
+is not extensive مش كتير كبير ال cell body و ال
+
+344
+00:24:18,740 --> 00:24:21,700
+neuron لمّا are intact اللي هو غشاء المحاطي في ال
+
+345
+00:24:21,700 --> 00:24:25,180
+neuron بيكون ما زال intact و ال scarring are not
+
+346
+00:24:25,180 --> 00:24:31,180
+okay مافيش عندنا عملية ال scarring أو أن ده موجودة
+
+347
+00:24:31,180 --> 00:24:34,740
+على ال neuron ال peripheral nerveالـ regeneration
+
+348
+00:24:34,740 --> 00:24:42,400
+of peripheral nervous system axons are invaluable
+
+349
+00:24:42,400 --> 00:24:46,780
+to cut and trauma طبعا أي axon ممكن انه يصير انصاب
+
+350
+00:24:46,780 --> 00:24:50,320
+بتراما ال damage of the axon can regenerate if
+
+351
+00:24:50,320 --> 00:24:53,680
+some of your gamma remains إذا لسه ال sheet تبع ال
+
+352
+00:24:53,680 --> 00:24:58,280
+axon لسه موجود ففيه فرصة انه يصير فيه regeneration
+
+353
+00:24:58,280 --> 00:25:02,560
+وبيعتمد على ال factor amount of damageوالـ
+
+354
+00:25:02,560 --> 00:25:07,240
+Neuroliminal Site Secretion of Nerve Growth Factor
+
+355
+00:25:07,240 --> 00:25:11,920
+طبعا تشير إلى أعضاء أكسونا السيورية والتقرير بين
+
+356
+00:25:11,920 --> 00:25:17,300
+موقع أكسونا الدمج والأفكتور يعني المسافة ما بين
+
+357
+00:25:17,300 --> 00:25:20,690
+الدمج اللي صارو مابين ال organ و هى اللى هتكون
+
+358
+00:25:20,690 --> 00:25:24,510
+هيضحى هنشوفها ادنا بالصورة طبعا ال regeneration
+
+359
+00:25:24,510 --> 00:25:29,310
+عملية صعبة شوية و very slow process يعنى تقريبا فى
+
+360
+00:25:29,310 --> 00:25:36,070
+ال human growth rate واحد point يعني واحد و نص
+
+361
+00:25:36,070 --> 00:25:40,270
+يولى meter per day فى ال human رابط اكتر فى حالات
+
+362
+00:25:40,270 --> 00:25:47,500
+ال rabbit لكن اذا كانهذه العملية بيكون أسرع أو
+
+363
+00:25:47,500 --> 00:25:50,660
+بتكون بهذا الريتم إذا كان فيه عنا .. مافيش عنا
+
+364
+00:25:50,660 --> 00:25:53,960
+infection، no infection و partially cut of the
+
+365
+00:25:53,960 --> 00:25:58,140
+axon مش complete cut هذا يعني أنه لنوري الملمة is
+
+366
+00:25:58,140 --> 00:26:01,740
+intact فregeneration start in the nerve cell by
+
+367
+00:26:01,740 --> 00:26:05,900
+resuming its normal shape and content طبعا لنوري
+
+368
+00:26:05,900 --> 00:26:10,740
+الفيبرل ال axons بالsprouts of the central stem
+
+369
+00:26:10,740 --> 00:26:18,220
+will grow تصير عنا entirethe entire the neurolimb
+
+370
+00:26:18,220 --> 00:26:23,080
+tube and the extent to the distal cut end of the
+
+371
+00:26:23,080 --> 00:26:26,860
+nerve هلقيت هنشوف هذا بالصور أكتر نشوف الصور الرقم
+
+372
+00:26:26,860 --> 00:26:30,200
+واحد صار في عندنا ال trauma على الأكسن لكن ال
+
+373
+00:26:30,200 --> 00:26:35,520
+healing shape لسه مازال موجود وفي عندنا مسافة بين
+
+374
+00:26:35,520 --> 00:26:39,580
+ال muscle أو ال skeletal muscle فلاقش اللي بتصير
+
+375
+00:26:39,580 --> 00:26:43,780
+المرحلة التانية انه بتصير ال end اللي موجودة عندنا
+
+376
+00:26:44,100 --> 00:26:48,960
+الـ end of the axon بتصير swollen و بتصير كده
+
+377
+00:26:48,960 --> 00:26:52,840
+متورمة زي أي حالة من ال inflammation بتصير وما
+
+378
+00:26:52,840 --> 00:26:56,560
+بعدها هنا إيش بيصير فيه؟ بيصير فيه degeneration
+
+379
+00:26:56,560 --> 00:27:03,430
+بعد هيك للمور و للمصيدعن طريق تجارب التجارب من
+
+380
+00:27:03,430 --> 00:27:06,850
+خلال تجارب تجارب ممتازة من خلال تجارب ممتازة من
+
+381
+00:27:06,850 --> 00:27:08,410
+خلال تجارب ممتازة من خلال تجارب ممتازة من خلال
+
+382
+00:27:08,410 --> 00:27:09,170
+تجارب ممتازة من خلال تجارب ممتازة من خلال تجارب
+
+383
+00:27:09,170 --> 00:27:09,750
+ممتازة من خلال تجارب ممتازة من خلال تجارب ممتازة
+
+384
+00:27:09,750 --> 00:27:09,750
+من خلال تجارب ممتازة من خلال تجارب ممتازة من خلال
+
+385
+00:27:09,750 --> 00:27:13,530
+تجارب ممتازة من خلال تجارب ممتازة من خلال تجارب
+
+386
+00:27:13,530 --> 00:27:25,630
+ممتازة من خلال تجارب ممتازة من خلال تجارب ممتاز
+
+387
+00:27:29,740 --> 00:27:33,700
+باسم الـ Neuroglia هي عبارة عن الـ connective
+
+388
+00:27:33,700 --> 00:27:37,740
+tissue في الـ central nervous system طبعا بدل ال
+
+389
+00:27:37,740 --> 00:27:41,360
+connective tissue فيه حاجة اسمها Neuroglia الـ
+
+390
+00:27:41,360 --> 00:27:46,720
+Neuroglia عبارة عن سلز موجودة supporting tissue أو
+
+391
+00:27:46,720 --> 00:27:51,340
+supporting tissue مش سلز between the neuron of the
+
+392
+00:27:51,340 --> 00:27:55,460
+central nervous system طبعا إلها أسماء شوية صعبة
+
+393
+00:27:55,460 --> 00:27:56,000
+زي ال
+
+394
+00:27:59,420 --> 00:28:09,020
+و Astrocytes و الابن ديما ال cells طبعا
+
+395
+00:28:09,020 --> 00:28:13,700
+هنا صورة أوضح بتوضح كيف بتصير عملية ال support
+
+396
+00:28:13,700 --> 00:28:17,260
+اللي موجودة و رابط ال axons مع بعض عن طريق ال
+
+397
+00:28:17,260 --> 00:28:23,040
+Oligodendrocytes اللي هي هذه و كيف ال Astrocytes
+
+398
+00:28:23,040 --> 00:28:27,140
+هنا بتساعد على التماسك
+
+399
+00:28:28,440 --> 00:28:32,600
+النيرونات مع بعضها طبعا مظيفتها تعملي support
+
+400
+00:28:32,600 --> 00:28:36,440
+similar to a function of connective tissue بتكون
+
+401
+00:28:36,440 --> 00:28:40,120
+لميالين شيطس around the axon وهو عبارة عن
+
+402
+00:28:40,120 --> 00:28:44,360
+insulators بتعمل عملية عزل بين ال نيرونات و
+
+403
+00:28:44,360 --> 00:28:49,360
+nutritive بتغذيها بتعمل defense against
+
+404
+00:28:49,360 --> 00:28:53,620
+inflammation وبتساعد في عملية ال regeneration وهذه
+
+405
+00:28:53,620 --> 00:28:59,230
+والمهمة السابعة انها بتعمل secretion ل CSFكماني
+
+406
+00:28:59,230 --> 00:29:02,730
+flow، هيك بيكون احنا نهينا محاضرتنا لليوم عن ال
+
+407
+00:29:02,730 --> 00:29:08,990
+nervous system و اتعرفنا عن ال cells كيف ال neuron
+
+408
+00:29:08,990 --> 00:29:13,350
+اشت مكوناته انه بتتكون من ال cell body و ال neuron
+
+409
+00:29:13,350 --> 00:29:18,070
+و ال axon و ال dendrites و قولنا ان وظيفة ال axon
+
+410
+00:29:18,070 --> 00:29:22,490
+convey يعني pure cellال .. ال impulse و ال
+
+411
+00:29:22,490 --> 00:29:25,190
+dendrites هو اللي بيستقبلها و قولنا ان ال central
+
+412
+00:29:25,190 --> 00:29:28,530
+nervous system بتكون من ال .. ال nervous system
+
+413
+00:29:28,530 --> 00:29:31,090
+بتكون من ال central nervous system on peripheral
+
+414
+00:29:31,090 --> 00:29:35,270
+nervous system و كمان اتعرفنا على أنواع ال nerves،
+
+415
+00:29:35,270 --> 00:29:38,410
+في عندنا sensory، في عندنا motor و في عندنا mixed
+
+416
+00:29:38,410 --> 00:29:42,660
+.. mixed nerveواتكلمنا عن انه في عندنا ال somatic
+
+417
+00:29:42,660 --> 00:29:46,080
+nervous system وفي ال autonomic nervous system
+
+418
+00:29:46,080 --> 00:29:50,080
+اللي هو الجهاز الإرادى واللا إرادى وذلك ان شاء
+
+419
+00:29:50,080 --> 00:29:53,000
+الله ننتقل في محاضرة جاية لجزء التانى من ال
+
+420
+00:29:53,000 --> 00:29:56,080
+nervous system واتاكم عافية نراكوا ان شاء الله في
+
+421
+00:29:56,080 --> 00:29:56,840
+الأسبوع المقبل
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/2ckWUqcnBh4.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/2ckWUqcnBh4.srt
new file mode 100644
index 0000000000000000000000000000000000000000..8965d8ead77a976ff2d98508775a6d34f8afa570
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/2ckWUqcnBh4.srt
@@ -0,0 +1,836 @@
+
+1
+00:00:04,930 --> 00:00:08,290
+نرجع لموضوع ال essential of human anatomy، اليوم
+
+2
+00:00:08,290 --> 00:00:11,690
+عندنا موضوع ال skeletal system، ال skeletal system
+
+3
+00:00:11,690 --> 00:00:18,030
+تقريبا هياخد معانا أربع محاضرات، هنتكلم فيه عن ال
+
+4
+00:00:18,030 --> 00:00:24,490
+bone، هنتكلم عن ال muscle، عن ال joints، عن ال
+
+5
+00:00:24,490 --> 00:00:31,050
+abdominal system، عن ال axial skeletal وهكذا بداية
+
+6
+00:00:31,050 --> 00:00:34,530
+حضرتنا اليوم عن ال bone، ال skeletal system هو
+
+7
+00:00:34,530 --> 00:00:41,210
+المكون الأساسي اللي هو ال bone لأنه هو الهيكل اللي
+
+8
+00:00:41,210 --> 00:00:46,900
+موقف عليه احنا أو بيعطينا الشكل العام تبع الجسم يبقى
+
+9
+00:00:46,900 --> 00:00:51,920
+ال bone is an .. ال bones are organs، هي عضو من
+
+10
+00:00:51,920 --> 00:00:55,120
+أعضاء الجسم، bones are composed of all tissue types
+
+11
+00:00:55,120 --> 00:01:01,120
+اللي تعرفنا عنها المرة اللي فاتت، ال primary
+
+12
+00:01:01,120 --> 00:01:05,840
+component is osseous connective tissue اللي هي ال
+
+13
+00:01:05,840 --> 00:01:13,800
+..المكوّن الأساسي للعظم اللي هو ال bone matrix is
+
+14
+00:01:13,800 --> 00:01:18,840
+sturdy and rigid due to mineralization، also called
+
+15
+00:01:18,840 --> 00:01:22,600
+mineralization، يبقى في عندنا معادن، مكونات في عندنا
+
+16
+00:01:22,600 --> 00:01:25,660
+connective tissue، في عندنا كالسيوم، في عندنا
+
+17
+00:01:25,660 --> 00:01:30,940
+بوتاسيوم وهكذا، كله مكوّن لل bone، What is the
+
+18
+00:01:30,940 --> 00:01:34,360
+function of the bone؟ طبعا أول حاجة support،
+
+19
+00:01:34,360 --> 00:01:37,940
+support، لأن هي بتعمل ال framework اللي احنا واقفين
+
+20
+00:01:37,940 --> 00:01:41,900
+عليه وبنقعد عليه وبننام عليه، كل هذا عبارة عن
+
+21
+00:01:41,900 --> 00:01:46,220
+شبكة أو framework أو لوحة that support the body
+
+22
+00:01:46,220 --> 00:01:53,960
+and cradle soft organs، بيحمي أو بيحيط ال soft
+
+23
+00:01:53,960 --> 00:01:58,520
+organs، الموجودة، protection، ليش protection؟ لأن
+
+24
+00:01:58,520 --> 00:02:04,070
+احنا بنلاقي الجمجمة بتحمي ال brain، ال vertebral
+
+25
+00:02:04,070 --> 00:02:07,990
+column بيحمي spinal cord، طبعا هذه كلها vital
+
+26
+00:02:07,990 --> 00:02:11,490
+organs، القفص الصدري بيحمي القلب والرئتين، فبيعمل
+
+27
+00:02:11,490 --> 00:02:14,670
+protection، movement، في عندي أنا muscles هي
+
+28
+00:02:14,670 --> 00:02:17,490
+بتعمل movement، فبالتالي هو provide ال levers، هو
+
+29
+00:02:17,490 --> 00:02:21,340
+الرافعات، ال bones هي الرافعة اللي بتتعامل
+
+30
+00:02:21,340 --> 00:02:25,240
+معاها العضلات عشان تعمل الحركة، طبعا ال mineral
+
+31
+00:02:25,240 --> 00:02:28,880
+storage هو عبارة عن تخزين ال minerals، especially
+
+32
+00:02:28,880 --> 00:02:34,080
+ال calcium والفسفور، blood cell formation، هو مصنع blood cell
+
+33
+00:02:34,080 --> 00:02:38,560
+formation، مصنع hemoptysis occurs within the marrow
+
+34
+00:02:38,560 --> 00:02:46,080
+cavities of the bone، في أن ال cavities الموجودة في
+
+35
+00:02:46,080 --> 00:02:51,420
+العظم أو النخاع العظمي هو اللي بيعمل مصنع ال blood
+
+36
+00:02:51,420 --> 00:02:55,240
+cells، أما ال energy store فهو في أن حاجة اسمها
+
+37
+00:02:55,240 --> 00:02:59,840
+yellow marrow، بيكون موجودة، احنا هنشوفها بوضوح
+
+38
+00:02:59,840 --> 00:03:03,540
+إيه هتكون، في عندي تخزين للدهون اللي بتعطيني تخزين
+
+39
+00:03:03,540 --> 00:03:10,040
+لل energy، support، bone provide structural support
+
+40
+00:03:10,040 --> 00:03:13,840
+and serve as a framework for the entire body، bone
+
+41
+00:03:13,840 --> 00:03:17,860
+protect many delicate tissues and organs from injury
+
+42
+00:03:17,860 --> 00:03:22,120
+and trauma، يعني تخيل أن شخص لو أخد ضربة في دماغه،
+
+43
+00:03:22,120 --> 00:03:26,480
+مش من السهل أنها تروح للـ brain، يعني تطلق الصدمة
+
+44
+00:03:26,480 --> 00:03:32,400
+مين؟ تطلق الصدمة الـ الـ الجمجمة
+
+45
+00:03:34,870 --> 00:03:38,690
+بالنسبة للـ movement، muscles، وين العضلات بتنشبك،
+
+46
+00:03:38,690 --> 00:03:41,090
+فيها origin and insertion، لازم يكون فيه عظم الـ
+
+47
+00:03:41,090 --> 00:03:44,350
+bone عشان أنا أعمل origin وأحطه ويكون فيه عظم ويكون
+
+48
+00:03:44,350 --> 00:03:46,910
+فيه insertion، يبقى muscle attached to the
+
+49
+00:03:46,910 --> 00:03:50,710
+bone of the skeleton contract and pull on the bone،
+
+50
+00:03:50,710 --> 00:03:55,640
+function as a series of levers، أما ال storage فعندنا
+
+51
+00:03:55,640 --> 00:04:00,660
+more than 90% of the body's reserves of mineral
+
+52
+00:04:00,660 --> 00:04:05,440
+calcium and phosphorus are stored in the bone, released
+
+53
+00:04:05,440 --> 00:04:08,880
+and unreleased by the bone، الهيماتوبوييسس هو
+
+54
+00:04:08,880 --> 00:04:12,880
+مصنع ال cell formation، مصنع خلايا الدم
+
+55
+00:04:12,880 --> 00:04:16,960
+production in the red bone marrow located in some
+
+56
+00:04:16,960 --> 00:04:21,180
+spongy bone، وحنشوفه الآن في تشريح ال bone نفسه أو
+
+57
+00:04:21,180 --> 00:04:25,190
+وصف ال bone نفسه، Red bone marrow contains stem
+
+58
+00:04:25,190 --> 00:04:30,890
+cells for all the blood cell types، أما ال
+
+59
+00:04:30,890 --> 00:04:37,230
+classification of the bone، فعندنا long bone زي ما
+
+60
+00:04:37,230 --> 00:04:41,010
+احنا شايفينها، اللي زي عظمة الفخذ أو عظمة الأيدي
+
+61
+00:04:41,010 --> 00:04:45,030
+والأرجل، عادة بتكون long bone، فعندنا short bone
+
+62
+00:04:45,030 --> 00:04:48,350
+القصيرة، زي اللي موجودة في ال carpals
+
+63
+00:04:51,710 --> 00:04:56,530
+وفي ال tarsals وال metatarsals، في عندنا ال flat
+
+64
+00:04:56,530 --> 00:05:00,730
+bones زي عظام الجمجمة وزي ال scapula، في irregular
+
+65
+00:05:00,730 --> 00:05:06,750
+bones اللي هي مش معروف لها شكل معين زي ال vertebrae
+
+66
+00:05:06,750 --> 00:05:11,490
+وفي ال sesamoid bones اللي بتكون عظام صغيرة مدورة
+
+67
+00:05:13,050 --> 00:05:16,690
+long bone زي ما احنا شايفين عظمة الهيمرَس اللي
+
+68
+00:05:16,690 --> 00:05:22,170
+موجودة في الذراع، هي long bone، طبعا في أطول عظمة
+
+69
+00:05:22,170 --> 00:05:25,590
+موجودة في الجسم، وأكبر عظمة اللي هي عظمة الفخذ
+
+70
+00:05:25,590 --> 00:05:31,130
+اللي هي هذه، عظمة الفخذ أو الفيمر، وهذه اسمها
+
+71
+00:05:31,130 --> 00:05:35,910
+الهيمرَس اللي هي عظمة الذراع
+
+72
+00:05:37,140 --> 00:05:40,900
+ال short bones، شايفين احنا بعض ال bones اللي موجودة
+
+73
+00:05:40,900 --> 00:05:44,560
+في الرسغ، ال cube shape bones of the wrist and the
+
+74
+00:05:44,560 --> 00:05:49,380
+ankle، ال bones that form within a tendon زي البطة
+
+75
+00:05:49,380 --> 00:05:55,350
+زي البطة مثلاً، احنا شايفينها في الركبة، ال flat bones احنا
+
+76
+00:05:55,350 --> 00:05:58,370
+شايفين ال sternum اللي هي عظمة القص، thing
+
+77
+00:05:58,370 --> 00:06:02,810
+flattened and a bit curved، زي ال sternum وكل ال
+
+78
+00:06:02,810 --> 00:06:07,570
+bones أو معظم bones of the skull، فينا irregular bones
+
+79
+00:06:07,570 --> 00:06:10,550
+زي ما احنا شايفين هنا، ال vertebrae هي irregular
+
+80
+00:06:10,550 --> 00:06:17,840
+bones، bones with complicated shapes، vertebrae and head
+
+81
+00:06:17,840 --> 00:06:24,520
+bones، زي ال  pelvic bone، هي كلها لأن شكلها غير
+
+82
+00:06:24,520 --> 00:06:28,720
+منتظم، هذا
+
+83
+00:06:28,720 --> 00:06:36,060
+طبعاً رسم توضيحي لل long bone وال flat bone، ال
+
+84
+00:06:36,060 --> 00:06:39,900
+short bones موجودة زي الكاربَلس مثلاً، ال irregular bones
+
+85
+00:06:39,900 --> 00:06:45,770
+زي ال vertebrae، طيب علاقة ال skeleton، احنا عندنا
+
+86
+00:06:45,770 --> 00:06:48,910
+اتنين من ال skeletons، عندنا ال axial skeleton و
+
+87
+00:06:48,910 --> 00:06:51,890
+عندنا ال appendicular skeleton، ال axial skeleton
+
+88
+00:06:51,890 --> 00:06:54,790
+اللي هو عبارة عن ال skull وال vertebral column وال
+
+89
+00:06:54,790 --> 00:06:58,630
+ال rib cage، فهذا المركزي أو المحوري أو المحور، ال
+
+90
+00:06:58,630 --> 00:07:01,870
+appendicular، دائماً من appendices أو appendix اللي
+
+91
+00:07:01,870 --> 00:07:08,410
+هي الأطراف زي ال lower limb وال upper limb، وطبعاً
+
+92
+00:07:08,410 --> 00:07:11,090
+لأن ال lower limb وال upper limb بيمسكوا
+
+93
+00:07:11,090 --> 00:07:17,890
+على حاجة اسمها girdles، وهذا الشكل بيوضح ال
+
+94
+00:07:17,890 --> 00:07:24,590
+skeleton، طبعاً هنا فيه ال head، ال vertebral column وال
+
+95
+00:07:24,590 --> 00:07:28,310
+ال rib cage، أما ال appendicular فهو ال shoulder
+
+96
+00:07:28,310 --> 00:07:31,650
+girdle مع ال upper limb وال pelvic girdle مع ال
+
+97
+00:07:31,650 --> 00:07:33,930
+lower limb
+
+98
+00:07:42,310 --> 00:07:45,210
+ال structure of the bone، فينا cartilage
+
+99
+00:07:45,210 --> 00:07:48,130
+protecting the joints
+
+100
+00:07:53,310 --> 00:07:59,510
+long bone، فيها epiphysis وفيها diaphysis، بالنسبة
+
+101
+00:07:59,510 --> 00:08:05,330
+لل epiphysis فهي أطراف العظمة، فوق وتحت،
+
+102
+00:08:05,330 --> 00:08:09,590
+expanded ends of the long bone، expanded ends of
+
+103
+00:08:09,590 --> 00:08:16,010
+the long bone، في عندنا حاجة بتغطي هذه ال ends عشان
+
+104
+00:08:16,010 --> 00:08:22,570
+تمنع الاحتكاك، عادة بتكون من الخارج compact bone ومن
+
+105
+00:08:22,570 --> 00:08:27,490
+الداخل spongy bone، وهنشوفها، ال joint surfaces
+
+106
+00:08:27,490 --> 00:08:32,570
+are covered by articular cartilage، located بيكون
+
+107
+00:08:32,570 --> 00:08:37,050
+فيها موجود في ال epiphysis، ال red bone marrow اللي هو
+
+108
+00:08:37,050 --> 00:08:40,790
+بيعمل formation ل blood cells، ال epiphyseal
+
+109
+00:08:40,790 --> 00:08:44,070
+line separates the diaphysis from the epiphysis،
+
+110
+00:08:44,070 --> 00:08:46,710
+وهو ال line of growth
+
+111
+00:08:53,010 --> 00:08:57,870
+أما ال diaphysis فهو الساق، يبقى tubular shaft
+
+112
+00:08:57,870 --> 00:09:02,790
+that forms the axis of the long bone، العظام الطويلة
+
+113
+00:09:02,790 --> 00:09:07,910
+هذه بيكون شكلها tube، طبعاً بتكون compact bone
+
+114
+00:09:07,910 --> 00:09:11,970
+من العظم القوي that surrounds the medullary cavity
+
+115
+00:09:11,970 --> 00:09:15,990
+اللي بيكون موجود فيها ال yellow bone marrow، هو
+
+116
+00:09:15,990 --> 00:09:19,170
+اللي قلنا مصدر الطاقة، is contained in the
+
+117
+00:09:19,170 --> 00:09:23,900
+medullary cavity، أما ال spongy bone زي ما احنا
+
+118
+00:09:23,900 --> 00:09:29,540
+شايفين هي عبارة عن ال red marrow زي ما شفناها في
+
+119
+00:09:29,540 --> 00:09:35,020
+السابق، أما ال yellow أو ال compact bone اللي بتكون
+
+120
+00:09:35,020 --> 00:09:39,840
+في ال shaft، ال compact and spongy bone، ال compact
+
+121
+00:09:39,840 --> 00:09:43,980
+اللي قولنا بتكون في ال long، تبع في ال shaft of the
+
+122
+00:09:43,980 --> 00:09:47,420
+bone، وزي ما احنا شايفينه بالرسم التوضيحي بيكون
+
+123
+00:09:47,420 --> 00:09:51,020
+compact bone وجوا في عندنا قناة بيكون فيها ال
+
+124
+00:09:51,020 --> 00:09:56,360
+yellow marrow، أما في ال epiphysis بيكون في
+
+125
+00:09:56,360 --> 00:10:01,270
+عندنا من الخارج compact bone وهنا من جوا spongy
+
+126
+00:10:01,270 --> 00:10:11,030
+bone، وبيكون في جواها قنوات لل red marrow طبعاً
+
+127
+00:10:11,030 --> 00:10:13,470
+من ال internal structure، في عندنا المدلولية ال
+
+128
+00:10:13,470 --> 00:10:16,530
+cavity، ال yellow في long bone، خلينا نقول في ال
+
+129
+00:10:16,530 --> 00:10:22,690
+short، في عندنا ال yellow marrow، فينا ال Epiphyseal
+
+130
+00:10:22,690 --> 00:10:26,230
+Plate أو ال Growth Plate اللي بيصير فيه من عنده ومن
+
+131
+00:10:26,230 --> 00:10:35,130
+خلاله النمو وطول العظام، هنا رسم توضيحي ل long
+
+132
+00:10:35,130 --> 00:10:42,750
+bone زي ما احنا شايفينها، في عندنا diaphysis، في
+
+133
+00:10:42,750 --> 00:10:45,610
+عندنا ال proximal epiphysis، في عندنا ال distal
+
+134
+00:10:45,610 --> 00:10:52,190
+epiphysis، في عندنا ال epiphyseal plates، في عندنا
+
+135
+00:10:53,400 --> 00:11:00,540
+هنا ال head يعني ال articular cartilage اللي بيغطي
+
+136
+00:11:00,540 --> 00:11:04,640
+ال head، ال spongy bone مكون ال epiphysis، قولنا فيه
+
+137
+00:11:04,640 --> 00:11:08,800
+ال قولنا ال red spaces لل red marrow في ال
+
+138
+00:11:08,800 --> 00:11:12,780
+endosteum، ال endosteum اللي هو الغشاء الداخلي اللي
+
+139
+00:11:12,780 --> 00:11:18,520
+بيغطي أو المبطن للعظام، وهنا من الخارج فينا ال compact
+
+140
+00:11:18,520 --> 00:11:22,010
+bone، وال medullary cavity اللي فيها ال yellow ال
+
+141
+00:11:22,010 --> 00:11:30,810
+bone marrow وال periosteum من الخارج طبعاً
+
+142
+00:11:30,810 --> 00:11:35,370
+شكل ال regular أو short أو ال flat bone مختلف شوية
+
+143
+00:11:35,370 --> 00:11:38,410
+لأن مافيش epiphysis ومافيش diaphysis، فهي غالباً
+
+144
+00:11:38,410 --> 00:11:43,030
+عبارة عن من الخارج compact bone ومن الداخل في عندنا
+
+145
+00:11:43,030 --> 00:11:44,670
+ال spongy bone
+
+146
+00:11:50,420 --> 00:11:54,140
+هي عبارة عن thin plates of periosteum covered with
+
+147
+00:11:54,140 --> 00:11:57,100
+a compact bone on the outside with the endosteum
+
+148
+00:11:57,100 --> 00:12:00,320
+covered with spongy bone on the inside، يبقى الـ
+
+149
+00:12:00,320 --> 00:12:03,940
+ال periosteum الغشاء الخارجي، ال endosteum هي
+
+150
+00:12:03,940 --> 00:12:08,540
+عبارة عن الغشاء الداخلي، مافيش لها diaphysis ولا
+
+151
+00:12:08,540 --> 00:12:14,140
+epiphysis، في عندها الـ الـ bone marrow بين اللي
+
+152
+00:12:14,140 --> 00:12:15,500
+بتتربي كلها
+
+153
+00:12:19,230 --> 00:12:23,250
+ال membranes، احنا كنا بنتكلم قبل شوية عن
+
+154
+00:12:23,250 --> 00:12:26,170
+ال periosteum وال endosteum، بلي، دائماً بتكون ال
+
+155
+00:12:26,170 --> 00:12:31,490
+outside، a double layer protective membrane، هي an
+
+156
+00:12:31,490 --> 00:12:35,610
+outer fibrous layer، لأنه من الخارج هو dense
+
+157
+00:12:35,610 --> 00:12:39,010
+irregular connective tissue، أما ال inner بيسموه
+
+158
+00:12:39,010 --> 00:12:42,280
+osteogenic layer، composed of osteoblasts and
+
+159
+00:12:42,280 --> 00:12:45,080
+osteoclasts، ال osteoblasts هي خلايا البناء في
+
+160
+00:12:45,080 --> 00:12:49,740
+العظم، وال osteoclasts هي خلايا الهدم، which is
+
+161
+00:12:49,740 --> 00:12:52,340
+supplied with nerve fibers، blood and
+
+162
+00:12:52,340 --> 00:12:55,580
+lymphatic vessels to the entire bone via
+
+163
+00:12:55,580 --> 00:12:59,140
+nutrient foramina
+
+164
+00:12:59,540 --> 00:13:04,060
+Secured to underlying bone by sharpey's fibers، أساس
+
+165
+00:13:04,060 --> 00:13:08,680
+أنه يمسك فيها، ال endosteum هو الغشاء الداخلي،
+
+166
+00:13:08,680 --> 00:13:12,000
+delicate membrane covering the internal surface of
+
+167
+00:13:12,000 --> 00:13:17,980
+the bone، ال blood supply طبعاً، ال periosteal arteries،
+
+168
+00:13:17,980 --> 00:13:21,000
+nutrient arteries وال metaphyseal وال
+
+169
+00:13:21,000 --> 00:13:27,280
+ال epiphyseal arteries، طبعاً ال periosteal arteries بتغذي
+
+170
+00:13:27,280 --> 00:13:31,220
+ال periosteum، وال nutrient arteries بتدخل ال nutrients على
+
+171
+00:13:31,220 --> 00:13:38,120
+ال foramina، supply ال compact bone وال red marrow، ال
+
+172
+00:13:38,120 --> 00:13:41,420
+metaphyseal وال epiphyseal arteries بتغذي ال red marrow وال
+
+173
+00:13:41,420 --> 00:13:46,160
+bone tissue of the epiphysis، طبعاً هنا ال bone
+
+174
+00:13:46,160 --> 00:13:52,600
+markings، أنا بدي أروح لمحاضرة أكثر توضيحاً لها
+
+175
+00:14:09,190 --> 00:14:15,210
+هنا طبعاً احنا بنتكلم عن markings، يعني بدنا علامات
+
+176
+00:14:15,210 --> 00:14:17,910
+يعني في كتير
+
+177
+00:14:19,860 --> 00:14:27,640
+أشكال أو خليني أقول حفور أو tuberosities، أماكن
+
+178
+00:14:27,640 --> 00:14:33,200
+بارزة في الجسم، نتعرف عليها، يعني every bump،
+
+179
+00:14:33,420 --> 00:14:38,260
+groove and hole has a name، في ال body
+
+180
+00:14:39,980 --> 00:14:44,560
+types of bone markings، projections، بروزات، وفي إن
+
+181
+00:14:44,560 --> 00:14:51,340
+أشياء هابطة أكثر، ال projections that
+
+182
+00:14:51,340 --> 00:14:57,020
+grow out from the bone، زي ال head مثلاً، زي ال
+
+183
+00:14:57,020 --> 00:15:00,360
+trochanters وهكذا، وفي إن ال depressions بتعمل
+
+184
+00:15:00,360 --> 00:15:05,620
+ca
+
+223
+00:18:25,150 --> 00:18:28,750
+زي شريخ كده بيكون موجود a slit-like opening
+
+224
+00:18:31,820 --> 00:18:34,980
+الـ sinuses زي ما احنا شايفين في عنا أكثر من زي
+
+225
+00:18:34,980 --> 00:18:40,620
+فتحات التهوية اللي موجودة في الـ skull cavity
+
+226
+00:18:40,620 --> 00:18:44,480
+within a bone, filled with air and lined with a
+
+227
+00:18:44,480 --> 00:18:50,160
+mucous membrane. الفرامين هي فتحات زي فتحة الحوض
+
+228
+00:18:50,160 --> 00:18:53,800
+اللي موجودة اللي بيفرج منها الـ baby زي الفتحات
+
+229
+00:18:53,800 --> 00:18:56,860
+اللي موجودة في الـ vertebral column عشان يمر فيها
+
+230
+00:18:56,860 --> 00:19:00,120
+اللي .. اللي هي القناة اللي بيمر فيها الـ spinal
+
+231
+00:19:00,120 --> 00:19:01,160
+cord
+
+232
+00:19:03,500 --> 00:19:07,140
+في الـ sulcus، الـ groove، و الـ fissure كلها عبارة عن زي
+
+233
+00:19:07,140 --> 00:19:11,560
+ما نسميه زي خندق ده أو groove، موجود بين مرتفعين
+
+234
+00:19:11,560 --> 00:19:15,120
+يعني بيكون multiple كده، حُفرة shallow depression زي
+
+235
+00:19:15,120 --> 00:19:20,140
+ما احنا شايفينها، الـ bicipital sulcus هذا بيمر فيه
+
+236
+00:19:20,140 --> 00:19:25,760
+الـ tendon of the biceps هذا موجود
+
+237
+00:19:25,760 --> 00:19:28,300
+في الـ humerus طبعا، اختصارا
+
+238
+00:19:30,750 --> 00:19:36,130
+الـ projections و الـ depressions. الـ projections زي
+
+239
+00:19:36,130 --> 00:19:39,650
+الـ condyle، الـ head، الـ facet، الـ ramus، الـ crest، الـ
+
+240
+00:19:39,650 --> 00:19:45,850
+epicondyle، الـ tubercle، الـ tuberosity، الـ
+
+241
+00:19:45,850 --> 00:19:50,370
+trochanter، الـ spine. أما الـ depressions زي الـ meatus
+
+242
+00:19:50,370 --> 00:19:56,780
+و الـ fossa، و الـ fissure، و الـ sinuses، و الـ
+
+243
+00:19:56,780 --> 00:20:01,720
+fossae and grooves. و بهيك احنا تقريبا بنكون ان
+
+244
+00:20:01,720 --> 00:20:06,920
+شاء الله أوجزنا محاضرتنا في الـ anatomy لليوم
+
+245
+00:20:09,090 --> 00:20:14,890
+مش هلأ، بنشوفكم يوم الأثنين بمحاضرة جديدة نستكمل
+
+246
+00:20:14,890 --> 00:20:21,170
+فيها محاضرة الـ … الـ …  the skeletal
+
+247
+00:20:21,170 --> 00:20:22,030
+system
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/2ckWUqcnBh4_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/2ckWUqcnBh4_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..38d28cc2059a3602b0e1c066e34e9a9715b65b7c
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/2ckWUqcnBh4_postprocess.srt
@@ -0,0 +1,988 @@
+1
+00:00:04,930 --> 00:00:08,290
+نرجع لموضوع ال essential of human anatomy، اليوم
+
+2
+00:00:08,290 --> 00:00:11,690
+عندنا موضوع ال skeletal system، ال skeletal system
+
+3
+00:00:11,690 --> 00:00:18,030
+تقريبا هياخد معانا أربع محاضرات، هنتكلم فيه عن ال
+
+4
+00:00:18,030 --> 00:00:24,490
+bone، هنتكلم عن ال muscle، عن ال joints، عن ال
+
+5
+00:00:24,490 --> 00:00:31,050
+abdominal system، عن ال axial skeletal و هكذابداية
+
+6
+00:00:31,050 --> 00:00:34,530
+حضرتنا اليوم عن ال bone ال skeletal system هو
+
+7
+00:00:34,530 --> 00:00:41,210
+المكون الأساسي اللي هو ال bone لأن هو الهيكل اللي
+
+8
+00:00:41,210 --> 00:00:46,900
+موقف عليه احنا أو بيعطينا الشكل العام تبع الرسمبقى
+
+9
+00:00:46,900 --> 00:00:51,920
+ال bone is an .. ال bones are organs هي عضو من
+
+10
+00:00:51,920 --> 00:00:55,120
+أعضاء الجسم، bone are composed of all tissue type
+
+11
+00:00:55,120 --> 00:01:01,120
+اللي تعرفنا عنها المرة اللي فاتت ال primary
+
+12
+00:01:01,120 --> 00:01:05,840
+component is osseous connective tissue اللي هي ال
+
+13
+00:01:05,840 --> 00:01:13,800
+..المكوّن الأساسي للعضم اللي هو ال bone matrix is
+
+14
+00:01:13,800 --> 00:01:18,840
+sturdy and rigid due classification also called
+
+15
+00:01:18,840 --> 00:01:22,600
+mineralization يبقى في عندنا معادن مكونات في عندنا
+
+16
+00:01:22,600 --> 00:01:25,660
+connective tissue في عندنا كالسيوم في عندنا
+
+17
+00:01:25,660 --> 00:01:30,940
+كوتاسيوم و هكذا كله مكوّن لل boneWhat is the
+
+18
+00:01:30,940 --> 00:01:34,360
+function of the bone؟ طبعا أول حاجة support
+
+19
+00:01:34,360 --> 00:01:37,940
+support لإن هي بتعمل ال framework اللي احنا واقفين
+
+20
+00:01:37,940 --> 00:01:41,900
+عليه و بنقعد عليه و بننام عليه كل هذا عبارة عن
+
+21
+00:01:41,900 --> 00:01:46,220
+شبكة او framework او لوحة that support the body
+
+22
+00:01:46,220 --> 00:01:53,960
+and cradle soft organs بيحمي او بيحيط ال soft
+
+23
+00:01:53,960 --> 00:01:58,520
+organs الموجودة ل protection ليش protection لإن
+
+24
+00:01:58,520 --> 00:02:04,070
+احنا بنلاقيالجنجمال بتحميل ال brain، ال vertebral
+
+25
+00:02:04,070 --> 00:02:07,990
+column بيحمل spinal cord طبعا هذه كلها vital
+
+26
+00:02:07,990 --> 00:02:11,490
+signs، القفص الصدري بيحمل قلب و رأتين فبيعمل
+
+27
+00:02:11,490 --> 00:02:14,670
+protection، ال movement في عندي أنا muscles هي
+
+28
+00:02:14,670 --> 00:02:17,490
+بتعمل movement فبالتالي هو provide ال liver، هو
+
+29
+00:02:17,490 --> 00:02:21,340
+الرافعاتال poor ال poor هي الرافعة اللى بتعامل
+
+30
+00:02:21,340 --> 00:02:25,240
+معاها العضلات عشان تعمل الحركة طبعا ال mineral
+
+31
+00:02:25,240 --> 00:02:28,880
+storage هو عبارة عن تخزين ال minerals especially
+
+32
+00:02:28,880 --> 00:02:34,080
+ال calcium و الفسفورBloods هو مصنع blood cell
+
+33
+00:02:34,080 --> 00:02:38,560
+formation مصنع hemoptysis occurs within the marrow
+
+34
+00:02:38,560 --> 00:02:46,080
+cavities of the bone في ان ال cavities الموجودة في
+
+35
+00:02:46,080 --> 00:02:51,420
+البون أو النخة العظمى هو اللى بيعملى مصنع ال blood
+
+36
+00:02:51,420 --> 00:02:55,240
+cells اما ال energy store فهو في ان حاجة اسمها
+
+37
+00:02:55,240 --> 00:02:59,840
+yellow marrow بيكون موجودة احنا هنشوفهابالواضحة
+
+38
+00:02:59,840 --> 00:03:03,540
+إيه هتكون في عندي تخزين للفت اللي بتعطييني تخزين
+
+39
+00:03:03,540 --> 00:03:10,040
+لل energy support bone provide structural support
+
+40
+00:03:10,040 --> 00:03:13,840
+and serve as a framework for the entire body bone
+
+41
+00:03:13,840 --> 00:03:17,860
+protect many delicate tissue organs from injury
+
+42
+00:03:17,860 --> 00:03:22,120
+and trauma يعنيتخيل أن شخص لو أخد ضربة في دماغه،
+
+43
+00:03:22,120 --> 00:03:26,480
+مش من السهل أنها تروح للـ brain، يعني تطلق الصدمة
+
+44
+00:03:26,480 --> 00:03:32,400
+مين؟ تطلق الصدمة ال .. ال .. الجنجمة
+
+45
+00:03:34,870 --> 00:03:38,690
+بالنسبة للـ movement، muscle وين العضلات بتنشبك،
+
+46
+00:03:38,690 --> 00:03:41,090
+فيها origin and insertion، لازم يكون فيه عين الـ
+
+47
+00:03:41,090 --> 00:03:44,350
+bone عشان أنا أعمل origin و أحطه و يكون فيه عيني و
+
+48
+00:03:44,350 --> 00:03:46,910
+يكون فيه insertion يبقى muscle attached to the
+
+49
+00:03:46,910 --> 00:03:50,710
+bone of the skeleton contract and pull on the bone
+
+50
+00:03:50,710 --> 00:03:55,640
+function as series of liversأما ال storage فعنا
+
+51
+00:03:55,640 --> 00:04:00,660
+more than 90% of the body's reserves of mineral
+
+52
+00:04:00,660 --> 00:04:05,440
+calcium and phosphorus are stored in the released
+
+53
+00:04:05,440 --> 00:04:08,880
+and unreleased by the bone الهي مبدوية السلهم هو
+
+54
+00:04:08,880 --> 00:04:12,880
+مصنع ال cell formation مصنع السل بلاي السل
+
+55
+00:04:12,880 --> 00:04:16,960
+production in the red bone marrow located in some
+
+56
+00:04:16,960 --> 00:04:21,180
+spongy bone وحنشوفه الآن في تشريح ال bone نفسه أو
+
+57
+00:04:21,180 --> 00:04:25,190
+وصف ال bone نفسهRed bone marrow contains stem
+
+58
+00:04:25,190 --> 00:04:30,890
+cells from all the blood cell type أما ال
+
+59
+00:04:30,890 --> 00:04:37,230
+classification of the bone فعنا long bone زي ما
+
+60
+00:04:37,230 --> 00:04:41,010
+أحنا شايفينها اللي زي عضمة الفخد أو عضمة الأيدين
+
+61
+00:04:41,010 --> 00:04:45,030
+والرجلين عادة بتكون long bone فعنا short bone
+
+62
+00:04:45,030 --> 00:04:48,350
+القصيرة زي اللي موجودة في ال carpel
+
+63
+00:04:51,710 --> 00:04:56,530
+و في الtersal و ال metatarsal فى عندنا ال flat
+
+64
+00:04:56,530 --> 00:05:00,730
+bone زى العضماط الجمجمة و زى ال scapula فى regular
+
+65
+00:05:00,730 --> 00:05:06,750
+bone اللى هى مش معروف لها شكل معين زى ال vertebra
+
+66
+00:05:06,750 --> 00:05:11,490
+و فى ال sesamoid bone اللى بتكون الأدام المدورة
+
+67
+00:05:13,050 --> 00:05:16,690
+long bone زى ما احنا شايفين عضمة الهيميراس اللى
+
+68
+00:05:16,690 --> 00:05:22,170
+موجودة فى الار فهى long bone طبعا فى اطول عضمة
+
+69
+00:05:22,170 --> 00:05:25,590
+موجودة فى الجسم و اكبر عضمة اللى هى عضمة الفخد
+
+70
+00:05:25,590 --> 00:05:31,130
+اللى هى هذه عضمة الفخد او الفيمر وهذه اسمها
+
+71
+00:05:31,130 --> 00:05:35,910
+الهيميراس اللى هى عضمة الذراع
+
+72
+00:05:37,140 --> 00:05:40,900
+ال short bone شايفين احنا بعض ال bones اللي موجودة
+
+73
+00:05:40,900 --> 00:05:44,560
+في القربة ال cube shape bones of the wrist and the
+
+74
+00:05:44,560 --> 00:05:49,380
+ankle ال bones that form within a tendon زي البتلة
+
+75
+00:05:49,380 --> 00:05:55,350
+زي البتلة مثلا احنا سابونة الرجلالـ flat bone احنا
+
+76
+00:05:55,350 --> 00:05:58,370
+شايفين الـ sternum اللي هي عضمة القص thing
+
+77
+00:05:58,370 --> 00:06:02,810
+flattened and bit curved زي ال sternum و كل ال
+
+78
+00:06:02,810 --> 00:06:07,570
+bone او مصد bones of the skull فينا irregular bone
+
+79
+00:06:07,570 --> 00:06:10,550
+زي ما احنا شايفين هنا ال vertebra هي irregular
+
+80
+00:06:10,550 --> 00:06:17,840
+bonebone with complicated shaped vertebra and head
+
+81
+00:06:17,840 --> 00:06:24,520
+bones زي ال perfect bone هي كلها لإن شكلها غير
+
+82
+00:06:24,520 --> 00:06:28,720
+منتظم هذا
+
+83
+00:06:28,720 --> 00:06:36,060
+طبعا رسم توضيحي لل long bone و ال flat bone ال
+
+84
+00:06:36,060 --> 00:06:39,900
+short bone موجودة زي التالس مثلا ال irregular bone
+
+85
+00:06:39,900 --> 00:06:45,770
+زي ال vertebraطيب علاقة ال skeleton احنا في عنا
+
+86
+00:06:45,770 --> 00:06:48,910
+اتنين من ال skeletons في عنا ال axial skeleton و
+
+87
+00:06:48,910 --> 00:06:51,890
+في عنا ال appendicular skeleton ال axial skeleton
+
+88
+00:06:51,890 --> 00:06:54,790
+اللي هو عبارة عن ال skull و ال vertebral column و
+
+89
+00:06:54,790 --> 00:06:58,630
+ال rib cage فهذا المركزي او المحوري او المحور ال
+
+90
+00:06:58,630 --> 00:07:01,870
+appendicular دائما من appendices او appendix اللي
+
+91
+00:07:01,870 --> 00:07:08,410
+هي الأطراف زي ال lower limb و ال upper limb و طبعا
+
+92
+00:07:08,410 --> 00:07:11,090
+عشان احنا ال lower limb و ال upper limb بيمسكوا
+
+93
+00:07:11,090 --> 00:07:17,890
+على حاجة اسمها girdlesو هذا الشكل بيوضحله ال
+
+94
+00:07:17,890 --> 00:07:24,590
+skeleton طبعا هنا فيه ال head ال vertebral colon و
+
+95
+00:07:24,590 --> 00:07:28,310
+ال rib cage أما ال abdicular فهو ال shoulder
+
+96
+00:07:28,310 --> 00:07:31,650
+girdle مع ال upper limb و ال pelvic girdle مع ال
+
+97
+00:07:31,650 --> 00:07:33,930
+lower limb
+
+98
+00:07:42,310 --> 00:07:45,210
+الـ structure of the bone فينا cartilage
+
+99
+00:07:45,210 --> 00:07:48,130
+protecting the joints
+
+100
+00:07:53,310 --> 00:07:59,510
+long bone فيها epiphysis و فيها diaphysis بالنسبة
+
+101
+00:07:59,510 --> 00:08:05,330
+لل epiphysis فهي أطراف العظمة فوق و من تحت
+
+102
+00:08:05,330 --> 00:08:09,590
+expanded ends of the long bone expanded ends of
+
+103
+00:08:09,590 --> 00:08:16,010
+the long bone في عندنا حاجة بتغطي هذه ال ends عشان
+
+104
+00:08:16,010 --> 00:08:22,570
+تمنع الاحتكاكعادة بتكون من الخارج compact bone و
+
+105
+00:08:22,570 --> 00:08:27,490
+من الداخل spongy bone و هنشوفها ال joint surfaces
+
+106
+00:08:27,490 --> 00:08:32,570
+is covered by articular cartilage located بيكون
+
+107
+00:08:32,570 --> 00:08:37,050
+فيها موجود في الepiphysis ال red bone مروء اللي هو
+
+108
+00:08:37,050 --> 00:08:40,790
+بيعمل ليه formation ل blood cells الepithelial
+
+109
+00:08:40,790 --> 00:08:44,070
+line separates the diaphysis from the epiphysis
+
+110
+00:08:44,070 --> 00:08:46,710
+وهو ال line of growth
+
+111
+00:08:53,010 --> 00:08:57,870
+أما الـdiaphysis فهو الشافط يبقى tubular shaft
+
+112
+00:08:57,870 --> 00:09:02,790
+that form the axis of the long bone العظام الطويلة
+
+113
+00:09:02,790 --> 00:09:07,910
+هذه بيكون فيها شكلها tube طبعا بتكون compact bone
+
+114
+00:09:07,910 --> 00:09:11,970
+من العظم القوي that surrounding المدلري cavity
+
+115
+00:09:11,970 --> 00:09:15,990
+اللي بيكون موجود فيها ال yellow bone marrow هو
+
+116
+00:09:15,990 --> 00:09:19,170
+اللي قلنا مصدر الطاقة is contained in the
+
+117
+00:09:19,170 --> 00:09:23,900
+medullary cavityأما ال sponge bone زي ما احنا
+
+118
+00:09:23,900 --> 00:09:29,540
+شايفين هي عبارة عن ال red marrow زي ما شوفناها في
+
+119
+00:09:29,540 --> 00:09:35,020
+السابق أما ال yellowأو الـ compact bone اللى بتكون
+
+120
+00:09:35,020 --> 00:09:39,840
+في ال shaft ال compact and spongy bone ال compact
+
+121
+00:09:39,840 --> 00:09:43,980
+اللى قولنا بتكون في ال long تبع في ال shaft of the
+
+122
+00:09:43,980 --> 00:09:47,420
+bone و زى ما احنا شايفينه بالرسم التوضيحى بيكون
+
+123
+00:09:47,420 --> 00:09:51,020
+compact bone و جوا في عندنا قناة بيكون فيها ال
+
+124
+00:09:51,020 --> 00:09:56,360
+yellow marrow اما في ال .. بالepiphysis بيكون في
+
+125
+00:09:56,360 --> 00:10:01,270
+عندنابس من الخارج compact pool وهنا من جوا spongy
+
+126
+00:10:01,270 --> 00:10:11,030
+boom وبيكون في جواها قنوات لرد مارو طبعا
+
+127
+00:10:11,030 --> 00:10:13,470
+من ال internal structure في عندنا المدالة ال
+
+128
+00:10:13,470 --> 00:10:16,530
+cavity ال yellow في long pond خلينا نقول في ال
+
+129
+00:10:16,530 --> 00:10:22,690
+short في عندنا ال yellow maroonفينا الـ Epiphyseal
+
+130
+00:10:22,690 --> 00:10:26,230
+Plate أو الـ Growth Plate اللي بيصير فيه من عنده و
+
+131
+00:10:26,230 --> 00:10:35,130
+من خلاله النمو و طول العظام هنا رسم توضيحي ل long
+
+132
+00:10:35,130 --> 00:10:42,750
+bone زي ما احنا شايفينهافي عندنا diaphysis في
+
+133
+00:10:42,750 --> 00:10:45,610
+عندنا ال proximal epiphysis في عندنا ال distal
+
+134
+00:10:45,610 --> 00:10:52,190
+epiphysis في عندنا ال epiphyseal blades في عندنا
+
+135
+00:10:53,400 --> 00:11:00,540
+هان ال head يعني ال articular cartilage اللي بيغطي
+
+136
+00:11:00,540 --> 00:11:04,640
+ال head ال sponge bone مكوّن ال epiphasis قولنا في
+
+137
+00:11:04,640 --> 00:11:08,800
+ال قولنا ال red spaces لل red marrow في ال
+
+138
+00:11:08,800 --> 00:11:12,780
+indestium ال indestium اللي هو الغشاء الداخلي اللي
+
+139
+00:11:12,780 --> 00:11:18,520
+بيغطي المبطن للعظام وهنا من الخارج فينا ال compact
+
+140
+00:11:18,520 --> 00:11:22,010
+boneو ال modellary cavity اللى فيها ال yellow ال
+
+141
+00:11:22,010 --> 00:11:30,810
+bone marrow و ال peristium من الخارج طبعا
+
+142
+00:11:30,810 --> 00:11:35,370
+شكل ال regular او short او ال flat bone مختلف شوية
+
+143
+00:11:35,370 --> 00:11:38,410
+لإن مافيش evil feces و مافيش ضياء feces فهى غالبا
+
+144
+00:11:38,410 --> 00:11:43,030
+عبارة من الخارج compact bone و من الداخل فى عندنا
+
+145
+00:11:43,030 --> 00:11:44,670
+ال spongy bone
+
+146
+00:11:50,420 --> 00:11:54,140
+هي عبارة عن thin plates of periosteum covered with
+
+147
+00:11:54,140 --> 00:11:57,100
+a compact bone on the outside with the endosteum
+
+148
+00:11:57,100 --> 00:12:00,320
+covered with spongy bone on the inside، يبقى ال ..
+
+149
+00:12:00,320 --> 00:12:03,940
+ال periosteum الغشاء الخارجي، ال endosteum هي
+
+150
+00:12:03,940 --> 00:12:08,540
+عبارة عن الغشاء الداخلي، مافيش إلها diaphysis ولا
+
+151
+00:12:08,540 --> 00:12:14,140
+epiphysis، في عندها ال .. ال bone مروء بين اللي
+
+152
+00:12:14,140 --> 00:12:15,500
+بتتربي كلها
+
+153
+00:12:19,230 --> 00:12:23,250
+الـ membranes احنا بتكون نتكلم قبل شوية عن
+
+154
+00:12:23,250 --> 00:12:26,170
+بيريوسيام مع أننا أندوسيام بليه دايما بتكون ال
+
+155
+00:12:26,170 --> 00:12:31,490
+outside ال double layer protective membrane هي an
+
+156
+00:12:31,490 --> 00:12:35,610
+outer fibrous layer لأنه من الخارج هو dense
+
+157
+00:12:35,610 --> 00:12:39,010
+regular connective tissue أما ال inner بيسموه
+
+158
+00:12:39,010 --> 00:12:42,280
+estrogenic layer composed ofosteoplast and
+
+159
+00:12:42,280 --> 00:12:45,080
+osteoclast، ال osteoplast هي خلايا البناء في
+
+160
+00:12:45,080 --> 00:12:49,740
+العضيم، وال osteoclast هي خلايا الهدم، which is
+
+161
+00:12:49,740 --> 00:12:52,340
+supplied with the nerve fibers, blood and
+
+162
+00:12:52,340 --> 00:12:55,580
+lymphatic vessels with the entire the bone via
+
+163
+00:12:55,580 --> 00:12:59,140
+nutrient foramen
+
+164
+00:12:59,540 --> 00:13:04,060
+Secured to underlying wound by sharpie fibers أساس
+
+165
+00:13:04,060 --> 00:13:08,680
+أنه يمسك فيها الاندوسيام هو الغشاء الداخلي،
+
+166
+00:13:08,680 --> 00:13:12,000
+delicate membrane covering the internal surface of
+
+167
+00:13:12,000 --> 00:13:17,980
+the wound ال blood supply طبعا البريسيال أرتراز،
+
+168
+00:13:17,980 --> 00:13:21,000
+ال nutrients أرتراز و ال metaphyseal و
+
+169
+00:13:21,000 --> 00:13:27,280
+الepiphyseal أرترازطبعا البريوستيرقاتر بيعزل
+
+170
+00:13:27,280 --> 00:13:31,220
+البريوستيان و ال nutrient بتدخل ال nutrients على
+
+171
+00:13:31,220 --> 00:13:38,120
+الفرامين supply ال compact bone و ال red marrow ال
+
+172
+00:13:38,120 --> 00:13:41,420
+metaphyseal و الepiphyseal supply ال red marrow و
+
+173
+00:13:41,420 --> 00:13:46,160
+ال bone tissue of the epiphysis طبعا هنا ال bone
+
+174
+00:13:46,160 --> 00:13:52,600
+marketing أنا بدي أروح لمحادرة أكتر توضيحا لإلها
+
+175
+00:14:09,190 --> 00:14:15,210
+هنا طبعا احنا نتكلم عن marketing يعني بدنا علامات
+
+176
+00:14:15,210 --> 00:14:17,910
+يعني في كتير
+
+177
+00:14:19,860 --> 00:14:27,640
+أشكال أو خلّيني أقول حفور أو tuberosities أماكن
+
+178
+00:14:27,640 --> 00:14:33,200
+بارزة في الجسم نتعرف هذه عليها يعني every pump,
+
+179
+00:14:33,420 --> 00:14:38,260
+groove and hole has a name في ال body
+
+180
+00:14:39,980 --> 00:14:44,560
+types of moon marketing projections بروزات وفي ان
+
+181
+00:14:44,560 --> 00:14:51,340
+اشياء لأ هابطة اكتر ال projections that
+
+182
+00:14:51,340 --> 00:14:57,020
+grow out from the moon زي ال head مثلا زي ال
+
+183
+00:14:57,020 --> 00:15:00,360
+trochanters و هكذا و في ان ال depressions بتعمل
+
+184
+00:15:00,360 --> 00:15:05,620
+cavities او بتعمل holes او بتعمل groovesداخل
+
+185
+00:15:05,620 --> 00:15:16,500
+العضمة زي ما احنا شايفين هنا على ال skull تكلم
+
+186
+00:15:16,500 --> 00:15:20,500
+عن ال projections زي الcondyle rounded articular
+
+187
+00:15:20,500 --> 00:15:25,380
+projection موجودين على ال epicondyle الcondyle تبع
+
+188
+00:15:25,380 --> 00:15:30,460
+نهاية العضمة وفيه بيجي بعدها ال epicondyle اشي
+
+189
+00:15:30,460 --> 00:15:39,850
+فوقها فوق الcondyleطبعا ال head pony expansions on
+
+190
+00:15:39,850 --> 00:15:44,730
+the narrow neck زي ما احنا شايفينها ال facet
+
+191
+00:15:44,730 --> 00:15:49,130
+smooth nearly flat articular surface يعني المنطقة
+
+192
+00:15:49,130 --> 00:15:55,870
+زي ال .. كده هابطة كده شوية بتكون smooth و flat
+
+193
+00:15:57,950 --> 00:16:04,730
+الرمس زى كأنها عاملة زى الـ arm bar زى ال .. ال ..
+
+194
+00:16:04,730 --> 00:16:09,890
+كده القديم of the bone زى تشوف هنا في ال escalate
+
+195
+00:16:09,890 --> 00:16:16,450
+شوف برزتي هذه عاملة زى ال .. ال arm هذه رمس سموها
+
+196
+00:16:20,400 --> 00:16:24,640
+الـ projections زي الـ crest مثلا narrow rigid of
+
+197
+00:16:24,640 --> 00:16:29,990
+the bone line smaller than a crestال lime ممكن
+
+198
+00:16:29,990 --> 00:16:35,210
+يكون اقل من الchrist ال a b condyle يكون فيه عندنا
+
+199
+00:16:35,210 --> 00:16:39,370
+raising above the condyle ممكن اه لو حسسنا احنا
+
+200
+00:16:39,370 --> 00:16:45,490
+فوق ال condyle هنا في ال upper limb في ال lower
+
+201
+00:16:45,490 --> 00:16:48,670
+end of the humerus بنحس ال condyle و ال a b
+
+202
+00:16:48,670 --> 00:16:51,630
+condyle و كده اللي في ال female كمعا
+
+203
+00:16:55,620 --> 00:16:58,520
+الـ tuberculosis هي عبارة عن بروز small rounded
+
+204
+00:16:58,520 --> 00:17:02,960
+projection أما الـ tuberosity فهي لأ بروز كبير
+
+205
+00:17:02,960 --> 00:17:07,240
+large rounded and roughened projection زي مثلا في
+
+206
+00:17:07,240 --> 00:17:10,880
+حاجة اسمها تيبيا ال tuberosity في مقدمة عضمة
+
+207
+00:17:10,880 --> 00:17:16,120
+التيبيا أسهل الرقبة والأتروكانتر لأ والله ده very
+
+208
+00:17:16,120 --> 00:17:20,420
+large blunt projection موجود بس في الفيمر بنسميه
+
+209
+00:17:20,420 --> 00:17:26,240
+ال greater etrocanter زي ما أحنا شايفين بالصورةالـ
+
+210
+00:17:26,240 --> 00:17:31,440
+spine .. spine شوكة sharp pointed projection زي
+
+211
+00:17:31,440 --> 00:17:34,600
+اللي موجودة في ال vertebra في ال posterior part of
+
+212
+00:17:34,600 --> 00:17:35,420
+the vertebra
+
+213
+00:17:38,350 --> 00:17:41,590
+and the depressions, the depressions allow the
+
+214
+00:17:41,590 --> 00:17:44,390
+blood vessels and nerves to pass through طبعا إيه
+
+215
+00:17:44,390 --> 00:17:51,170
+حلوة لو ال blood vessels و ال nerves موجودة على
+
+216
+00:17:51,170 --> 00:17:56,610
+السفح كانت بيكون مقلمة جدا و بيكون عرضة لإنها تصاب
+
+217
+00:17:56,610 --> 00:17:59,610
+و كمان لازم يكون في إلها passages عشان تتعدى
+
+218
+00:17:59,610 --> 00:18:05,730
+الmiatas شكل زي هكذا قناة أو YouTubeتسميها mietas
+
+219
+00:18:05,730 --> 00:18:10,410
+طبعا كل واحدة إلها اسم و مكان محدد الفصة shallow
+
+220
+00:18:10,410 --> 00:18:15,790
+زي الفصة ال glenoid فصة ال glenoid فصة هي ال
+
+221
+00:18:15,790 --> 00:18:19,350
+articulation ما بين ال head of the humerus و ال
+
+222
+00:18:19,350 --> 00:18:25,150
+scapula أنا ماشي بالرسم هنا في ال scapula الفشر مش
+
+223
+00:18:25,150 --> 00:18:28,750
+زي شريخ كده بيكون موجود slit-like opening
+
+224
+00:18:31,820 --> 00:18:34,980
+الـ sinuses زي ما احنا شايفين في عنا اكتر من زي
+
+225
+00:18:34,980 --> 00:18:40,620
+فتحات التهوية اللي موجودة في ال .. ال skull cavity
+
+226
+00:18:40,620 --> 00:18:44,480
+within a bone filled with air and lined with a
+
+227
+00:18:44,480 --> 00:18:50,160
+mucous membrane الفراميون هي فتحات زي فتحة الحوض
+
+228
+00:18:50,160 --> 00:18:53,800
+اللي موجودة اللي بيفرج منها ال baby زي الفتحات
+
+229
+00:18:53,800 --> 00:18:56,860
+اللي موجودة في ال vertebral column عشان يمر فيها
+
+230
+00:18:56,860 --> 00:19:00,120
+اللي .. اللي هي القناع اللي بيمر فيها ال spinal
+
+231
+00:19:00,120 --> 00:19:01,160
+cord
+
+232
+00:19:03,500 --> 00:19:07,140
+في الـ Sulcus الـ groove و الفرو كلها عبارة عن زي
+
+233
+00:19:07,140 --> 00:19:11,560
+ما نسميه زي خندق ده أو groove موجود بين مرتفعين
+
+234
+00:19:11,560 --> 00:19:15,120
+يعني بيكون multiple كده حطة shallow depression زي
+
+235
+00:19:15,120 --> 00:19:20,140
+ما احنا شايفينها ال bicepital sulcus هذا بيمرق في
+
+236
+00:19:20,140 --> 00:19:25,760
+ال timber of the biceps هذا موجود
+
+237
+00:19:25,760 --> 00:19:28,300
+في الهيمراس طبعا اختصار
+
+238
+00:19:30,750 --> 00:19:36,130
+ال projections و ال depressions ال projections زي
+
+239
+00:19:36,130 --> 00:19:39,650
+ال condyle ال head الفصة الرامس ال crest ال
+
+240
+00:19:39,650 --> 00:19:45,850
+epicondyle ال .. ال tubercle ال tuberosity ال
+
+241
+00:19:45,850 --> 00:19:50,370
+trochanter ال spine أما ال depressions زي المياتس
+
+242
+00:19:50,370 --> 00:19:56,780
+و الفصةو ال .. و ال fisher و ال sinuses و ال
+
+243
+00:19:56,780 --> 00:20:01,720
+sarcas and group or .. و بهيك احنا تقريبا بنكون ان
+
+244
+00:20:01,720 --> 00:20:06,920
+شاء الله أوجزنا محاضرتنا لل anatomy لليوم
+
+245
+00:20:09,090 --> 00:20:14,890
+مش هلأ بنشوفكم اليوم الأتنين بمحاضرة جديدة نستكمل
+
+246
+00:20:14,890 --> 00:20:21,170
+فيها محاضرة ال .. ال .. masculine .. ال skeletal
+
+247
+00:20:21,170 --> 00:20:22,030
+system
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/2ckWUqcnBh4_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/2ckWUqcnBh4_raw.json
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index 0000000000000000000000000000000000000000..77cb10e90837e6e4cc79a595e988f166ee68c6c3
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@@ -0,0 +1 @@
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appendix اللي هي الأطراف زي ال lower limb و ال upper limb و طبعا عشان احنا ال lower limb و ال upper limb بيمسكوا على حاجة اسمها girdles", "tokens": [9566, 1829, 3555, 11203, 995, 28671, 2423, 25204, 1975, 5016, 8315, 8978, 6225, 8315, 1975, 2655, 1863, 9957, 9154, 2423, 45538, 8978, 6225, 8315, 2423, 46851, 25204, 4032, 8978, 6225, 8315, 2423, 34116, 14646, 25204, 2423, 46851, 25204, 13672, 1829, 31439, 6225, 3555, 9640, 3660, 18871, 2423, 11743, 4032, 2423, 16167, 32728, 7738, 4032, 2423, 9162, 17302, 6156, 3224, 15730, 9673, 31747, 11622, 1829, 1975, 2407, 9673, 5016, 13063, 1829, 1975, 2407, 9673, 5016, 13063, 2423, 34116, 14646, 11778, 16373, 15042, 9154, 34116, 1473, 1975, 2407, 34116, 970, 13672, 1829, 39896, 16247, 9566, 23557, 5172, 30767, 1829, 2423, 3126, 30390, 4032, 2423, 6597, 30390, 4032, 23032, 3555, 3615, 995, 6225, 8592, 7649, 1975, 5016, 8315, 2423, 3126, 30390, 4032, 2423, 6597, 30390, 4724, 32640, 3794, 4117, 14407, 15844, 11331, 26108, 3660, 24525, 2304, 11296, 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0.95458984375}, {"start": 1204.72, "end": 1205.02, "word": " لل", "probability": 0.92626953125}, {"start": 1205.02, "end": 1205.6, "word": " anatomy", "probability": 0.720703125}, {"start": 1205.6, "end": 1206.92, "word": " لليوم", "probability": 0.9119466145833334}], "temperature": 1.0}, {"id": 53, "seek": 122203, "start": 1209.09, "end": 1222.03, "text": "مش هلأ بنشوفكم اليوم الأتنين بمحاضرة جديدة نستكمل فيها محاضرة ال .. ال .. masculine .. ال skeletal system", "tokens": [2304, 8592, 8032, 1211, 10721, 44945, 8592, 38688, 24793, 45595, 20498, 16247, 2655, 1863, 9957, 4724, 2304, 5016, 46958, 25720, 10874, 16254, 41891, 8717, 14851, 24793, 1211, 8978, 11296, 3714, 5016, 46958, 25720, 2423, 4386, 2423, 4386, 28992, 4386, 2423, 32321, 304, 1185], "avg_logprob": -0.21750710769133133, "compression_ratio": 1.2834645669291338, "no_speech_prob": 1.1920928955078125e-06, "words": [{"start": 1209.09, "end": 1209.37, "word": "مش", "probability": 0.939697265625}, {"start": 1209.37, "end": 1209.57, "word": " هلأ", "probability": 0.7882486979166666}, {"start": 1209.57, "end": 1210.27, "word": " بنشوفكم", "probability": 0.865234375}, {"start": 1210.27, "end": 1211.05, "word": " اليوم", "probability": 0.6663818359375}, {"start": 1211.05, "end": 1211.69, "word": " الأتنين", "probability": 0.77899169921875}, {"start": 1211.69, "end": 1213.53, "word": " بمحاضرة", "probability": 0.92529296875}, {"start": 1213.53, "end": 1214.15, "word": " جديدة", "probability": 0.9889322916666666}, {"start": 1214.15, "end": 1214.89, "word": " نستكمل", "probability": 0.916748046875}, {"start": 1214.89, "end": 1215.43, "word": " فيها", "probability": 0.98291015625}, {"start": 1215.43, "end": 1216.69, "word": " محاضرة", "probability": 0.9820556640625}, {"start": 1216.69, "end": 1217.05, "word": " ال", "probability": 0.4990234375}, {"start": 1217.05, "end": 1217.71, "word": " ..", "probability": 0.6396484375}, {"start": 1217.71, "end": 1219.75, "word": " ال", "probability": 0.82470703125}, {"start": 1219.75, "end": 1220.11, "word": " ..", "probability": 0.381591796875}, {"start": 1220.11, "end": 1220.25, "word": " masculine", "probability": 0.231689453125}, {"start": 1220.25, "end": 1220.43, "word": " ..", "probability": 0.74169921875}, {"start": 1220.43, "end": 1220.57, "word": " ال", "probability": 0.5927734375}, {"start": 1220.57, "end": 1221.17, "word": " skeletal", "probability": 0.912109375}, {"start": 1221.17, "end": 1222.03, "word": " system", "probability": 0.9814453125}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1222.5538125, "duration_after_vad": 1150.7056249999996}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/2ckWUqcnBh4_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/2ckWUqcnBh4_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..38d28cc2059a3602b0e1c066e34e9a9715b65b7c
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/2ckWUqcnBh4_raw.srt
@@ -0,0 +1,988 @@
+1
+00:00:04,930 --> 00:00:08,290
+نرجع لموضوع ال essential of human anatomy، اليوم
+
+2
+00:00:08,290 --> 00:00:11,690
+عندنا موضوع ال skeletal system، ال skeletal system
+
+3
+00:00:11,690 --> 00:00:18,030
+تقريبا هياخد معانا أربع محاضرات، هنتكلم فيه عن ال
+
+4
+00:00:18,030 --> 00:00:24,490
+bone، هنتكلم عن ال muscle، عن ال joints، عن ال
+
+5
+00:00:24,490 --> 00:00:31,050
+abdominal system، عن ال axial skeletal و هكذابداية
+
+6
+00:00:31,050 --> 00:00:34,530
+حضرتنا اليوم عن ال bone ال skeletal system هو
+
+7
+00:00:34,530 --> 00:00:41,210
+المكون الأساسي اللي هو ال bone لأن هو الهيكل اللي
+
+8
+00:00:41,210 --> 00:00:46,900
+موقف عليه احنا أو بيعطينا الشكل العام تبع الرسمبقى
+
+9
+00:00:46,900 --> 00:00:51,920
+ال bone is an .. ال bones are organs هي عضو من
+
+10
+00:00:51,920 --> 00:00:55,120
+أعضاء الجسم، bone are composed of all tissue type
+
+11
+00:00:55,120 --> 00:01:01,120
+اللي تعرفنا عنها المرة اللي فاتت ال primary
+
+12
+00:01:01,120 --> 00:01:05,840
+component is osseous connective tissue اللي هي ال
+
+13
+00:01:05,840 --> 00:01:13,800
+..المكوّن الأساسي للعضم اللي هو ال bone matrix is
+
+14
+00:01:13,800 --> 00:01:18,840
+sturdy and rigid due classification also called
+
+15
+00:01:18,840 --> 00:01:22,600
+mineralization يبقى في عندنا معادن مكونات في عندنا
+
+16
+00:01:22,600 --> 00:01:25,660
+connective tissue في عندنا كالسيوم في عندنا
+
+17
+00:01:25,660 --> 00:01:30,940
+كوتاسيوم و هكذا كله مكوّن لل boneWhat is the
+
+18
+00:01:30,940 --> 00:01:34,360
+function of the bone؟ طبعا أول حاجة support
+
+19
+00:01:34,360 --> 00:01:37,940
+support لإن هي بتعمل ال framework اللي احنا واقفين
+
+20
+00:01:37,940 --> 00:01:41,900
+عليه و بنقعد عليه و بننام عليه كل هذا عبارة عن
+
+21
+00:01:41,900 --> 00:01:46,220
+شبكة او framework او لوحة that support the body
+
+22
+00:01:46,220 --> 00:01:53,960
+and cradle soft organs بيحمي او بيحيط ال soft
+
+23
+00:01:53,960 --> 00:01:58,520
+organs الموجودة ل protection ليش protection لإن
+
+24
+00:01:58,520 --> 00:02:04,070
+احنا بنلاقيالجنجمال بتحميل ال brain، ال vertebral
+
+25
+00:02:04,070 --> 00:02:07,990
+column بيحمل spinal cord طبعا هذه كلها vital
+
+26
+00:02:07,990 --> 00:02:11,490
+signs، القفص الصدري بيحمل قلب و رأتين فبيعمل
+
+27
+00:02:11,490 --> 00:02:14,670
+protection، ال movement في عندي أنا muscles هي
+
+28
+00:02:14,670 --> 00:02:17,490
+بتعمل movement فبالتالي هو provide ال liver، هو
+
+29
+00:02:17,490 --> 00:02:21,340
+الرافعاتال poor ال poor هي الرافعة اللى بتعامل
+
+30
+00:02:21,340 --> 00:02:25,240
+معاها العضلات عشان تعمل الحركة طبعا ال mineral
+
+31
+00:02:25,240 --> 00:02:28,880
+storage هو عبارة عن تخزين ال minerals especially
+
+32
+00:02:28,880 --> 00:02:34,080
+ال calcium و الفسفورBloods هو مصنع blood cell
+
+33
+00:02:34,080 --> 00:02:38,560
+formation مصنع hemoptysis occurs within the marrow
+
+34
+00:02:38,560 --> 00:02:46,080
+cavities of the bone في ان ال cavities الموجودة في
+
+35
+00:02:46,080 --> 00:02:51,420
+البون أو النخة العظمى هو اللى بيعملى مصنع ال blood
+
+36
+00:02:51,420 --> 00:02:55,240
+cells اما ال energy store فهو في ان حاجة اسمها
+
+37
+00:02:55,240 --> 00:02:59,840
+yellow marrow بيكون موجودة احنا هنشوفهابالواضحة
+
+38
+00:02:59,840 --> 00:03:03,540
+إيه هتكون في عندي تخزين للفت اللي بتعطييني تخزين
+
+39
+00:03:03,540 --> 00:03:10,040
+لل energy support bone provide structural support
+
+40
+00:03:10,040 --> 00:03:13,840
+and serve as a framework for the entire body bone
+
+41
+00:03:13,840 --> 00:03:17,860
+protect many delicate tissue organs from injury
+
+42
+00:03:17,860 --> 00:03:22,120
+and trauma يعنيتخيل أن شخص لو أخد ضربة في دماغه،
+
+43
+00:03:22,120 --> 00:03:26,480
+مش من السهل أنها تروح للـ brain، يعني تطلق الصدمة
+
+44
+00:03:26,480 --> 00:03:32,400
+مين؟ تطلق الصدمة ال .. ال .. الجنجمة
+
+45
+00:03:34,870 --> 00:03:38,690
+بالنسبة للـ movement، muscle وين العضلات بتنشبك،
+
+46
+00:03:38,690 --> 00:03:41,090
+فيها origin and insertion، لازم يكون فيه عين الـ
+
+47
+00:03:41,090 --> 00:03:44,350
+bone عشان أنا أعمل origin و أحطه و يكون فيه عيني و
+
+48
+00:03:44,350 --> 00:03:46,910
+يكون فيه insertion يبقى muscle attached to the
+
+49
+00:03:46,910 --> 00:03:50,710
+bone of the skeleton contract and pull on the bone
+
+50
+00:03:50,710 --> 00:03:55,640
+function as series of liversأما ال storage فعنا
+
+51
+00:03:55,640 --> 00:04:00,660
+more than 90% of the body's reserves of mineral
+
+52
+00:04:00,660 --> 00:04:05,440
+calcium and phosphorus are stored in the released
+
+53
+00:04:05,440 --> 00:04:08,880
+and unreleased by the bone الهي مبدوية السلهم هو
+
+54
+00:04:08,880 --> 00:04:12,880
+مصنع ال cell formation مصنع السل بلاي السل
+
+55
+00:04:12,880 --> 00:04:16,960
+production in the red bone marrow located in some
+
+56
+00:04:16,960 --> 00:04:21,180
+spongy bone وحنشوفه الآن في تشريح ال bone نفسه أو
+
+57
+00:04:21,180 --> 00:04:25,190
+وصف ال bone نفسهRed bone marrow contains stem
+
+58
+00:04:25,190 --> 00:04:30,890
+cells from all the blood cell type أما ال
+
+59
+00:04:30,890 --> 00:04:37,230
+classification of the bone فعنا long bone زي ما
+
+60
+00:04:37,230 --> 00:04:41,010
+أحنا شايفينها اللي زي عضمة الفخد أو عضمة الأيدين
+
+61
+00:04:41,010 --> 00:04:45,030
+والرجلين عادة بتكون long bone فعنا short bone
+
+62
+00:04:45,030 --> 00:04:48,350
+القصيرة زي اللي موجودة في ال carpel
+
+63
+00:04:51,710 --> 00:04:56,530
+و في الtersal و ال metatarsal فى عندنا ال flat
+
+64
+00:04:56,530 --> 00:05:00,730
+bone زى العضماط الجمجمة و زى ال scapula فى regular
+
+65
+00:05:00,730 --> 00:05:06,750
+bone اللى هى مش معروف لها شكل معين زى ال vertebra
+
+66
+00:05:06,750 --> 00:05:11,490
+و فى ال sesamoid bone اللى بتكون الأدام المدورة
+
+67
+00:05:13,050 --> 00:05:16,690
+long bone زى ما احنا شايفين عضمة الهيميراس اللى
+
+68
+00:05:16,690 --> 00:05:22,170
+موجودة فى الار فهى long bone طبعا فى اطول عضمة
+
+69
+00:05:22,170 --> 00:05:25,590
+موجودة فى الجسم و اكبر عضمة اللى هى عضمة الفخد
+
+70
+00:05:25,590 --> 00:05:31,130
+اللى هى هذه عضمة الفخد او الفيمر وهذه اسمها
+
+71
+00:05:31,130 --> 00:05:35,910
+الهيميراس اللى هى عضمة الذراع
+
+72
+00:05:37,140 --> 00:05:40,900
+ال short bone شايفين احنا بعض ال bones اللي موجودة
+
+73
+00:05:40,900 --> 00:05:44,560
+في القربة ال cube shape bones of the wrist and the
+
+74
+00:05:44,560 --> 00:05:49,380
+ankle ال bones that form within a tendon زي البتلة
+
+75
+00:05:49,380 --> 00:05:55,350
+زي البتلة مثلا احنا سابونة الرجلالـ flat bone احنا
+
+76
+00:05:55,350 --> 00:05:58,370
+شايفين الـ sternum اللي هي عضمة القص thing
+
+77
+00:05:58,370 --> 00:06:02,810
+flattened and bit curved زي ال sternum و كل ال
+
+78
+00:06:02,810 --> 00:06:07,570
+bone او مصد bones of the skull فينا irregular bone
+
+79
+00:06:07,570 --> 00:06:10,550
+زي ما احنا شايفين هنا ال vertebra هي irregular
+
+80
+00:06:10,550 --> 00:06:17,840
+bonebone with complicated shaped vertebra and head
+
+81
+00:06:17,840 --> 00:06:24,520
+bones زي ال perfect bone هي كلها لإن شكلها غير
+
+82
+00:06:24,520 --> 00:06:28,720
+منتظم هذا
+
+83
+00:06:28,720 --> 00:06:36,060
+طبعا رسم توضيحي لل long bone و ال flat bone ال
+
+84
+00:06:36,060 --> 00:06:39,900
+short bone موجودة زي التالس مثلا ال irregular bone
+
+85
+00:06:39,900 --> 00:06:45,770
+زي ال vertebraطيب علاقة ال skeleton احنا في عنا
+
+86
+00:06:45,770 --> 00:06:48,910
+اتنين من ال skeletons في عنا ال axial skeleton و
+
+87
+00:06:48,910 --> 00:06:51,890
+في عنا ال appendicular skeleton ال axial skeleton
+
+88
+00:06:51,890 --> 00:06:54,790
+اللي هو عبارة عن ال skull و ال vertebral column و
+
+89
+00:06:54,790 --> 00:06:58,630
+ال rib cage فهذا المركزي او المحوري او المحور ال
+
+90
+00:06:58,630 --> 00:07:01,870
+appendicular دائما من appendices او appendix اللي
+
+91
+00:07:01,870 --> 00:07:08,410
+هي الأطراف زي ال lower limb و ال upper limb و طبعا
+
+92
+00:07:08,410 --> 00:07:11,090
+عشان احنا ال lower limb و ال upper limb بيمسكوا
+
+93
+00:07:11,090 --> 00:07:17,890
+على حاجة اسمها girdlesو هذا الشكل بيوضحله ال
+
+94
+00:07:17,890 --> 00:07:24,590
+skeleton طبعا هنا فيه ال head ال vertebral colon و
+
+95
+00:07:24,590 --> 00:07:28,310
+ال rib cage أما ال abdicular فهو ال shoulder
+
+96
+00:07:28,310 --> 00:07:31,650
+girdle مع ال upper limb و ال pelvic girdle مع ال
+
+97
+00:07:31,650 --> 00:07:33,930
+lower limb
+
+98
+00:07:42,310 --> 00:07:45,210
+الـ structure of the bone فينا cartilage
+
+99
+00:07:45,210 --> 00:07:48,130
+protecting the joints
+
+100
+00:07:53,310 --> 00:07:59,510
+long bone فيها epiphysis و فيها diaphysis بالنسبة
+
+101
+00:07:59,510 --> 00:08:05,330
+لل epiphysis فهي أطراف العظمة فوق و من تحت
+
+102
+00:08:05,330 --> 00:08:09,590
+expanded ends of the long bone expanded ends of
+
+103
+00:08:09,590 --> 00:08:16,010
+the long bone في عندنا حاجة بتغطي هذه ال ends عشان
+
+104
+00:08:16,010 --> 00:08:22,570
+تمنع الاحتكاكعادة بتكون من الخارج compact bone و
+
+105
+00:08:22,570 --> 00:08:27,490
+من الداخل spongy bone و هنشوفها ال joint surfaces
+
+106
+00:08:27,490 --> 00:08:32,570
+is covered by articular cartilage located بيكون
+
+107
+00:08:32,570 --> 00:08:37,050
+فيها موجود في الepiphysis ال red bone مروء اللي هو
+
+108
+00:08:37,050 --> 00:08:40,790
+بيعمل ليه formation ل blood cells الepithelial
+
+109
+00:08:40,790 --> 00:08:44,070
+line separates the diaphysis from the epiphysis
+
+110
+00:08:44,070 --> 00:08:46,710
+وهو ال line of growth
+
+111
+00:08:53,010 --> 00:08:57,870
+أما الـdiaphysis فهو الشافط يبقى tubular shaft
+
+112
+00:08:57,870 --> 00:09:02,790
+that form the axis of the long bone العظام الطويلة
+
+113
+00:09:02,790 --> 00:09:07,910
+هذه بيكون فيها شكلها tube طبعا بتكون compact bone
+
+114
+00:09:07,910 --> 00:09:11,970
+من العظم القوي that surrounding المدلري cavity
+
+115
+00:09:11,970 --> 00:09:15,990
+اللي بيكون موجود فيها ال yellow bone marrow هو
+
+116
+00:09:15,990 --> 00:09:19,170
+اللي قلنا مصدر الطاقة is contained in the
+
+117
+00:09:19,170 --> 00:09:23,900
+medullary cavityأما ال sponge bone زي ما احنا
+
+118
+00:09:23,900 --> 00:09:29,540
+شايفين هي عبارة عن ال red marrow زي ما شوفناها في
+
+119
+00:09:29,540 --> 00:09:35,020
+السابق أما ال yellowأو الـ compact bone اللى بتكون
+
+120
+00:09:35,020 --> 00:09:39,840
+في ال shaft ال compact and spongy bone ال compact
+
+121
+00:09:39,840 --> 00:09:43,980
+اللى قولنا بتكون في ال long تبع في ال shaft of the
+
+122
+00:09:43,980 --> 00:09:47,420
+bone و زى ما احنا شايفينه بالرسم التوضيحى بيكون
+
+123
+00:09:47,420 --> 00:09:51,020
+compact bone و جوا في عندنا قناة بيكون فيها ال
+
+124
+00:09:51,020 --> 00:09:56,360
+yellow marrow اما في ال .. بالepiphysis بيكون في
+
+125
+00:09:56,360 --> 00:10:01,270
+عندنابس من الخارج compact pool وهنا من جوا spongy
+
+126
+00:10:01,270 --> 00:10:11,030
+boom وبيكون في جواها قنوات لرد مارو طبعا
+
+127
+00:10:11,030 --> 00:10:13,470
+من ال internal structure في عندنا المدالة ال
+
+128
+00:10:13,470 --> 00:10:16,530
+cavity ال yellow في long pond خلينا نقول في ال
+
+129
+00:10:16,530 --> 00:10:22,690
+short في عندنا ال yellow maroonفينا الـ Epiphyseal
+
+130
+00:10:22,690 --> 00:10:26,230
+Plate أو الـ Growth Plate اللي بيصير فيه من عنده و
+
+131
+00:10:26,230 --> 00:10:35,130
+من خلاله النمو و طول العظام هنا رسم توضيحي ل long
+
+132
+00:10:35,130 --> 00:10:42,750
+bone زي ما احنا شايفينهافي عندنا diaphysis في
+
+133
+00:10:42,750 --> 00:10:45,610
+عندنا ال proximal epiphysis في عندنا ال distal
+
+134
+00:10:45,610 --> 00:10:52,190
+epiphysis في عندنا ال epiphyseal blades في عندنا
+
+135
+00:10:53,400 --> 00:11:00,540
+هان ال head يعني ال articular cartilage اللي بيغطي
+
+136
+00:11:00,540 --> 00:11:04,640
+ال head ال sponge bone مكوّن ال epiphasis قولنا في
+
+137
+00:11:04,640 --> 00:11:08,800
+ال قولنا ال red spaces لل red marrow في ال
+
+138
+00:11:08,800 --> 00:11:12,780
+indestium ال indestium اللي هو الغشاء الداخلي اللي
+
+139
+00:11:12,780 --> 00:11:18,520
+بيغطي المبطن للعظام وهنا من الخارج فينا ال compact
+
+140
+00:11:18,520 --> 00:11:22,010
+boneو ال modellary cavity اللى فيها ال yellow ال
+
+141
+00:11:22,010 --> 00:11:30,810
+bone marrow و ال peristium من الخارج طبعا
+
+142
+00:11:30,810 --> 00:11:35,370
+شكل ال regular او short او ال flat bone مختلف شوية
+
+143
+00:11:35,370 --> 00:11:38,410
+لإن مافيش evil feces و مافيش ضياء feces فهى غالبا
+
+144
+00:11:38,410 --> 00:11:43,030
+عبارة من الخارج compact bone و من الداخل فى عندنا
+
+145
+00:11:43,030 --> 00:11:44,670
+ال spongy bone
+
+146
+00:11:50,420 --> 00:11:54,140
+هي عبارة عن thin plates of periosteum covered with
+
+147
+00:11:54,140 --> 00:11:57,100
+a compact bone on the outside with the endosteum
+
+148
+00:11:57,100 --> 00:12:00,320
+covered with spongy bone on the inside، يبقى ال ..
+
+149
+00:12:00,320 --> 00:12:03,940
+ال periosteum الغشاء الخارجي، ال endosteum هي
+
+150
+00:12:03,940 --> 00:12:08,540
+عبارة عن الغشاء الداخلي، مافيش إلها diaphysis ولا
+
+151
+00:12:08,540 --> 00:12:14,140
+epiphysis، في عندها ال .. ال bone مروء بين اللي
+
+152
+00:12:14,140 --> 00:12:15,500
+بتتربي كلها
+
+153
+00:12:19,230 --> 00:12:23,250
+الـ membranes احنا بتكون نتكلم قبل شوية عن
+
+154
+00:12:23,250 --> 00:12:26,170
+بيريوسيام مع أننا أندوسيام بليه دايما بتكون ال
+
+155
+00:12:26,170 --> 00:12:31,490
+outside ال double layer protective membrane هي an
+
+156
+00:12:31,490 --> 00:12:35,610
+outer fibrous layer لأنه من الخارج هو dense
+
+157
+00:12:35,610 --> 00:12:39,010
+regular connective tissue أما ال inner بيسموه
+
+158
+00:12:39,010 --> 00:12:42,280
+estrogenic layer composed ofosteoplast and
+
+159
+00:12:42,280 --> 00:12:45,080
+osteoclast، ال osteoplast هي خلايا البناء في
+
+160
+00:12:45,080 --> 00:12:49,740
+العضيم، وال osteoclast هي خلايا الهدم، which is
+
+161
+00:12:49,740 --> 00:12:52,340
+supplied with the nerve fibers, blood and
+
+162
+00:12:52,340 --> 00:12:55,580
+lymphatic vessels with the entire the bone via
+
+163
+00:12:55,580 --> 00:12:59,140
+nutrient foramen
+
+164
+00:12:59,540 --> 00:13:04,060
+Secured to underlying wound by sharpie fibers أساس
+
+165
+00:13:04,060 --> 00:13:08,680
+أنه يمسك فيها الاندوسيام هو الغشاء الداخلي،
+
+166
+00:13:08,680 --> 00:13:12,000
+delicate membrane covering the internal surface of
+
+167
+00:13:12,000 --> 00:13:17,980
+the wound ال blood supply طبعا البريسيال أرتراز،
+
+168
+00:13:17,980 --> 00:13:21,000
+ال nutrients أرتراز و ال metaphyseal و
+
+169
+00:13:21,000 --> 00:13:27,280
+الepiphyseal أرترازطبعا البريوستيرقاتر بيعزل
+
+170
+00:13:27,280 --> 00:13:31,220
+البريوستيان و ال nutrient بتدخل ال nutrients على
+
+171
+00:13:31,220 --> 00:13:38,120
+الفرامين supply ال compact bone و ال red marrow ال
+
+172
+00:13:38,120 --> 00:13:41,420
+metaphyseal و الepiphyseal supply ال red marrow و
+
+173
+00:13:41,420 --> 00:13:46,160
+ال bone tissue of the epiphysis طبعا هنا ال bone
+
+174
+00:13:46,160 --> 00:13:52,600
+marketing أنا بدي أروح لمحادرة أكتر توضيحا لإلها
+
+175
+00:14:09,190 --> 00:14:15,210
+هنا طبعا احنا نتكلم عن marketing يعني بدنا علامات
+
+176
+00:14:15,210 --> 00:14:17,910
+يعني في كتير
+
+177
+00:14:19,860 --> 00:14:27,640
+أشكال أو خلّيني أقول حفور أو tuberosities أماكن
+
+178
+00:14:27,640 --> 00:14:33,200
+بارزة في الجسم نتعرف هذه عليها يعني every pump,
+
+179
+00:14:33,420 --> 00:14:38,260
+groove and hole has a name في ال body
+
+180
+00:14:39,980 --> 00:14:44,560
+types of moon marketing projections بروزات وفي ان
+
+181
+00:14:44,560 --> 00:14:51,340
+اشياء لأ هابطة اكتر ال projections that
+
+182
+00:14:51,340 --> 00:14:57,020
+grow out from the moon زي ال head مثلا زي ال
+
+183
+00:14:57,020 --> 00:15:00,360
+trochanters و هكذا و في ان ال depressions بتعمل
+
+184
+00:15:00,360 --> 00:15:05,620
+cavities او بتعمل holes او بتعمل groovesداخل
+
+185
+00:15:05,620 --> 00:15:16,500
+العضمة زي ما احنا شايفين هنا على ال skull تكلم
+
+186
+00:15:16,500 --> 00:15:20,500
+عن ال projections زي الcondyle rounded articular
+
+187
+00:15:20,500 --> 00:15:25,380
+projection موجودين على ال epicondyle الcondyle تبع
+
+188
+00:15:25,380 --> 00:15:30,460
+نهاية العضمة وفيه بيجي بعدها ال epicondyle اشي
+
+189
+00:15:30,460 --> 00:15:39,850
+فوقها فوق الcondyleطبعا ال head pony expansions on
+
+190
+00:15:39,850 --> 00:15:44,730
+the narrow neck زي ما احنا شايفينها ال facet
+
+191
+00:15:44,730 --> 00:15:49,130
+smooth nearly flat articular surface يعني المنطقة
+
+192
+00:15:49,130 --> 00:15:55,870
+زي ال .. كده هابطة كده شوية بتكون smooth و flat
+
+193
+00:15:57,950 --> 00:16:04,730
+الرمس زى كأنها عاملة زى الـ arm bar زى ال .. ال ..
+
+194
+00:16:04,730 --> 00:16:09,890
+كده القديم of the bone زى تشوف هنا في ال escalate
+
+195
+00:16:09,890 --> 00:16:16,450
+شوف برزتي هذه عاملة زى ال .. ال arm هذه رمس سموها
+
+196
+00:16:20,400 --> 00:16:24,640
+الـ projections زي الـ crest مثلا narrow rigid of
+
+197
+00:16:24,640 --> 00:16:29,990
+the bone line smaller than a crestال lime ممكن
+
+198
+00:16:29,990 --> 00:16:35,210
+يكون اقل من الchrist ال a b condyle يكون فيه عندنا
+
+199
+00:16:35,210 --> 00:16:39,370
+raising above the condyle ممكن اه لو حسسنا احنا
+
+200
+00:16:39,370 --> 00:16:45,490
+فوق ال condyle هنا في ال upper limb في ال lower
+
+201
+00:16:45,490 --> 00:16:48,670
+end of the humerus بنحس ال condyle و ال a b
+
+202
+00:16:48,670 --> 00:16:51,630
+condyle و كده اللي في ال female كمعا
+
+203
+00:16:55,620 --> 00:16:58,520
+الـ tuberculosis هي عبارة عن بروز small rounded
+
+204
+00:16:58,520 --> 00:17:02,960
+projection أما الـ tuberosity فهي لأ بروز كبير
+
+205
+00:17:02,960 --> 00:17:07,240
+large rounded and roughened projection زي مثلا في
+
+206
+00:17:07,240 --> 00:17:10,880
+حاجة اسمها تيبيا ال tuberosity في مقدمة عضمة
+
+207
+00:17:10,880 --> 00:17:16,120
+التيبيا أسهل الرقبة والأتروكانتر لأ والله ده very
+
+208
+00:17:16,120 --> 00:17:20,420
+large blunt projection موجود بس في الفيمر بنسميه
+
+209
+00:17:20,420 --> 00:17:26,240
+ال greater etrocanter زي ما أحنا شايفين بالصورةالـ
+
+210
+00:17:26,240 --> 00:17:31,440
+spine .. spine شوكة sharp pointed projection زي
+
+211
+00:17:31,440 --> 00:17:34,600
+اللي موجودة في ال vertebra في ال posterior part of
+
+212
+00:17:34,600 --> 00:17:35,420
+the vertebra
+
+213
+00:17:38,350 --> 00:17:41,590
+and the depressions, the depressions allow the
+
+214
+00:17:41,590 --> 00:17:44,390
+blood vessels and nerves to pass through طبعا إيه
+
+215
+00:17:44,390 --> 00:17:51,170
+حلوة لو ال blood vessels و ال nerves موجودة على
+
+216
+00:17:51,170 --> 00:17:56,610
+السفح كانت بيكون مقلمة جدا و بيكون عرضة لإنها تصاب
+
+217
+00:17:56,610 --> 00:17:59,610
+و كمان لازم يكون في إلها passages عشان تتعدى
+
+218
+00:17:59,610 --> 00:18:05,730
+الmiatas شكل زي هكذا قناة أو YouTubeتسميها mietas
+
+219
+00:18:05,730 --> 00:18:10,410
+طبعا كل واحدة إلها اسم و مكان محدد الفصة shallow
+
+220
+00:18:10,410 --> 00:18:15,790
+زي الفصة ال glenoid فصة ال glenoid فصة هي ال
+
+221
+00:18:15,790 --> 00:18:19,350
+articulation ما بين ال head of the humerus و ال
+
+222
+00:18:19,350 --> 00:18:25,150
+scapula أنا ماشي بالرسم هنا في ال scapula الفشر مش
+
+223
+00:18:25,150 --> 00:18:28,750
+زي شريخ كده بيكون موجود slit-like opening
+
+224
+00:18:31,820 --> 00:18:34,980
+الـ sinuses زي ما احنا شايفين في عنا اكتر من زي
+
+225
+00:18:34,980 --> 00:18:40,620
+فتحات التهوية اللي موجودة في ال .. ال skull cavity
+
+226
+00:18:40,620 --> 00:18:44,480
+within a bone filled with air and lined with a
+
+227
+00:18:44,480 --> 00:18:50,160
+mucous membrane الفراميون هي فتحات زي فتحة الحوض
+
+228
+00:18:50,160 --> 00:18:53,800
+اللي موجودة اللي بيفرج منها ال baby زي الفتحات
+
+229
+00:18:53,800 --> 00:18:56,860
+اللي موجودة في ال vertebral column عشان يمر فيها
+
+230
+00:18:56,860 --> 00:19:00,120
+اللي .. اللي هي القناع اللي بيمر فيها ال spinal
+
+231
+00:19:00,120 --> 00:19:01,160
+cord
+
+232
+00:19:03,500 --> 00:19:07,140
+في الـ Sulcus الـ groove و الفرو كلها عبارة عن زي
+
+233
+00:19:07,140 --> 00:19:11,560
+ما نسميه زي خندق ده أو groove موجود بين مرتفعين
+
+234
+00:19:11,560 --> 00:19:15,120
+يعني بيكون multiple كده حطة shallow depression زي
+
+235
+00:19:15,120 --> 00:19:20,140
+ما احنا شايفينها ال bicepital sulcus هذا بيمرق في
+
+236
+00:19:20,140 --> 00:19:25,760
+ال timber of the biceps هذا موجود
+
+237
+00:19:25,760 --> 00:19:28,300
+في الهيمراس طبعا اختصار
+
+238
+00:19:30,750 --> 00:19:36,130
+ال projections و ال depressions ال projections زي
+
+239
+00:19:36,130 --> 00:19:39,650
+ال condyle ال head الفصة الرامس ال crest ال
+
+240
+00:19:39,650 --> 00:19:45,850
+epicondyle ال .. ال tubercle ال tuberosity ال
+
+241
+00:19:45,850 --> 00:19:50,370
+trochanter ال spine أما ال depressions زي المياتس
+
+242
+00:19:50,370 --> 00:19:56,780
+و الفصةو ال .. و ال fisher و ال sinuses و ال
+
+243
+00:19:56,780 --> 00:20:01,720
+sarcas and group or .. و بهيك احنا تقريبا بنكون ان
+
+244
+00:20:01,720 --> 00:20:06,920
+شاء الله أوجزنا محاضرتنا لل anatomy لليوم
+
+245
+00:20:09,090 --> 00:20:14,890
+مش هلأ بنشوفكم اليوم الأتنين بمحاضرة جديدة نستكمل
+
+246
+00:20:14,890 --> 00:20:21,170
+فيها محاضرة ال .. ال .. masculine .. ال skeletal
+
+247
+00:20:21,170 --> 00:20:22,030
+system
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs.srt
new file mode 100644
index 0000000000000000000000000000000000000000..ba192f486cd28d43530245fef6cc0679d10f107a
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs.srt
@@ -0,0 +1,1023 @@
+1
+00:00:04,980 --> 00:00:09,940
+بسم الله الرحمن الرحيم طلابنا الأعزاء، اليوم
+
+2
+00:00:09,940 --> 00:00:14,260
+استكمالًا لمحاضرات skeletal system، الجزء الثاني من
+
+3
+00:00:14,260 --> 00:00:17,680
+المحاضرة، سنتكلم فيها عن الـ axial skeleton، اللي هو
+
+4
+00:00:17,680 --> 00:00:25,390
+بيتمثل بالـ head، والـ trunk، والـ vertebral column.
+
+5
+00:00:25,390 --> 00:00:29,790
+إن شاء الله تكون الصور التوضيحية الموجودة معنا
+
+6
+00:00:29,790 --> 00:00:33,690
+في الـ presentation، تساعد في الشرح.  كان من المفترض أن
+
+7
+00:00:33,690 --> 00:00:36,770
+يكون معنا الـ skeleton اليوم، لكن مع صعوبة
+
+8
+00:00:36,770 --> 00:00:39,450
+التنقل، قلت الصور إن شاء الله تكون توضيحية
+
+9
+00:00:39,450 --> 00:00:44,980
+وتعطينا فكرة عن الـ axial skeleton، بشكل طبيعي.
+
+10
+00:00:44,980 --> 00:00:48,320
+يتكون من الـ head، والـ neck، والـ trunk، الـ trunk
+
+11
+00:00:48,320 --> 00:00:54,860
+طبعًا اللي هو يشمل الجدع، ما نسميه نحن الجزء،
+
+12
+00:00:54,860 --> 00:00:59,520
+أما الـ appendicular system أو skeleton، فهو عبارة
+
+13
+00:00:59,520 --> 00:01:03,250
+عن الـ upper limbs، والـ lower limbs، والـ pectoral girdle، والـ
+
+14
+00:01:03,250 --> 00:01:08,170
+pelvic girdle. طبعًا المحاضرة القادمة إن
+
+15
+00:01:08,170 --> 00:01:10,910
+شاء الله ستكون عن الـ appendicular system. اليوم سنتكلم
+
+16
+00:01:10,910 --> 00:01:16,070
+عن الـ axial skeleton. الـ axial skeleton، حسب ما هو
+
+17
+00:01:16,070 --> 00:01:22,950
+موضح بالرسم، يتضمن الـ head، بكل العظام المكونة
+
+18
+00:01:22,950 --> 00:01:28,670
+لـ skull، وفي عندنا الـ neck، وفي عندنا الـ thoracic cage،
+
+19
+00:01:28,670 --> 00:01:33,910
+كما هو موضح بالرسم، والـ vertebral column أيضًا.
+
+20
+00:01:33,910 --> 00:01:38,850
+سنتكلم عنهم بالتفصيل إن شاء الله. طبعًا الـ skull هي
+
+21
+00:01:38,850 --> 00:01:43,390
+عبارة عن الجمجمة، التي وظيفتها أنها تحتوي على ثماني
+
+22
+00:01:43,390 --> 00:01:49,650
+عظام. هذه وظيفتها أنها تحيط وتغلق على الـ
+
+23
+00:01:49,650 --> 00:01:54,290
+brain. طبعًا في عظام الوجه، الـ face bones، هي
+
+24
+00:01:54,290 --> 00:02:00,350
+اثنتا عشرة عظمة، وظيفتها أنها تعمل ممرات لـ
+
+25
+00:02:00,350 --> 00:02:04,650
+الـ digestive و الـ respiratory systems، وتعمل مداخل
+
+26
+00:02:04,650 --> 00:02:09,990
+وكذلك تعطينا مكانًا لعضلات الوجه، اللي هي
+
+27
+00:02:09,990 --> 00:02:15,630
+بتؤثر على تعابير الوجه، وتكون ملتصقة في
+
+28
+00:02:15,630 --> 00:02:22,210
+هذه العظام. طبعًا بالنسبة للـ cranium، نحن كلنا
+
+29
+00:02:22,210 --> 00:02:26,410
+حافظين أنه في عندنا عظام رئيسية وكبيرة، مثل الـ
+
+30
+00:02:26,410 --> 00:02:32,230
+frontal bone، كما هو موضح بهذا الشكل، هي عظمة
+
+31
+00:02:32,230 --> 00:02:38,030
+كبيرة، اللي هي عظمة الجبهة، وفي عندنا الـ parietal، وفي
+
+32
+00:02:38,030 --> 00:02:41,230
+عندنا عظمتان، هي الـ frontal عظمة واحدة، لكن في عندنا
+
+33
+00:02:41,230 --> 00:02:47,490
+عظمتان موجودتان في جانبي الجمجمة، هي الـ parietal، و
+
+34
+00:02:47,490 --> 00:02:53,070
+تحتها مباشرةً يكون في عندنا الـ occipital، في خلفية
+
+35
+00:02:53,070 --> 00:02:58,930
+الرأس، عظمة واحدة، وكما هنا الـ temporal، اللي هي فوق
+
+36
+00:02:58,930 --> 00:03:03,850
+الأذن ومحيط الأذن، في عندنا عظمتان على الناحية الأخرى.
+
+37
+00:03:03,850 --> 00:03:07,290
+طبعًا نحن من الـ 80 cranial bones، نحن نتكلم عن
+
+38
+00:03:07,290 --> 00:03:12,910
+العظام الرئيسية، أن في أكثر من ثمانية، لأنه في
+
+39
+00:03:12,910 --> 00:03:19,310
+أزواج، وفي عظمة واحدة فقط. الشكل هنا واضح بالعظام
+
+40
+00:03:19,310 --> 00:03:25,850
+الموجودة، وأماكن تواجدها تمامًا. الـ skull، نقول
+
+41
+00:03:25,850 --> 00:03:31,190
+هي تشكل الحماية للـ brain، وفي نفس الوقت فيها
+
+42
+00:03:31,190 --> 00:03:34,790
+تجاويف، الـ cavities هذه، ما وظيفتها؟
+
+43
+00:03:37,430 --> 00:03:40,570
+مثل تجويف الدماغ، أو الـ cranial cavity، هي أكبر cavity
+
+44
+00:03:40,570 --> 00:03:44,830
+تقريبًا موجودة في هذه المنطقة، تغلق وتعمل
+
+45
+00:03:44,830 --> 00:03:48,870
+وسائد للـ brain، تحمي الـ brain، و كذلك من
+
+46
+00:03:48,870 --> 00:03:52,590
+خلال الأغشية، اللي موجودة، تشكل حماية أكبر، و
+
+47
+00:03:52,590 --> 00:03:56,550
+تعمل امتصاص للصدمات أيضًا، لأي صدمة، لأننا نعلم
+
+48
+00:03:56,550 --> 00:04:01,290
+أن الـ brain جزء حساس من جسم الإنسان، وهو عبارة عن
+
+49
+00:04:01,290 --> 00:04:04,950
+مركز التحكم للجسم كله، وبالتالي يحتاج لحماية كبيرة
+
+50
+00:04:04,950 --> 00:04:09,050
+جداً، لكنه ليس مكوّن من عظمة واحدة، لأنه
+
+51
+00:04:09,050 --> 00:04:12,390
+هذه العظام، مجموعة العظام هذه، مع الفتحات التي
+
+52
+00:04:12,390 --> 00:04:17,690
+بينها، تسمح بالنمو، أيضًا في فتحات أخرى، لأن
+
+53
+00:04:17,690 --> 00:04:22,770
+العيون موجودة، أيضًا، في فتحات نسميها الـ
+
+54
+00:04:22,770 --> 00:04:27,010
+orbits، وفي التجويف الفموي، اللي هو يمثل الـ
+
+55
+00:04:27,010 --> 00:04:30,150
+mouth، لنتمكن من الأكل، وفي التجويف الأنفي، والـ
+
+56
+00:04:30,150 --> 00:04:34,090
+paranasal sinuses، من أجل الـ
+
+57
+00:04:35,890 --> 00:04:42,270
+مساعدة في عملية التنفس. الـ Paranasal Sinuses هذه
+
+58
+00:04:42,270 --> 00:04:50,210
+تساعد أيضًا في ارتجاج الصوت، لما نحن مصدر الصوت، طبعًا
+
+59
+00:04:50,210 --> 00:04:53,510
+هنا العظام الصغيرة هذه موضحة بالرسم، مثل الـ
+
+60
+00:04:53,510 --> 00:04:57,870
+sphenoid، والـ
+
+61
+00:04:57,870 --> 00:05:03,430
+ethmoid، والـ maxillary. هنا عظام الوجه الآن، فأنا
+
+62
+00:05:03,430 --> 00:05:06,230
+أتحدث عن الـ facial skeleton. الـ maxillary،
+
+63
+00:05:06,230 --> 00:05:12,910
+اللي هي عظمة الفك العلوي، والـ palatine، ما هي
+
+64
+00:05:12,910 --> 00:05:19,470
+موضحة بالرسم، فوق الفك العلوي، والـ zygomatic، هي
+
+65
+00:05:19,470 --> 00:05:26,730
+اللي هي عبارة عن عظام الخد، عظام الخد، اللي هي تحت
+
+66
+00:05:26,730 --> 00:05:35,550
+العين، وتنزل حول الأنف، والـ vomer، طبعًا
+
+67
+00:05:35,550 --> 00:05:44,170
+في الكثير منها، حسب الرسم، جميع عظام الوجه، والـ
+
+68
+00:05:44,170 --> 00:05:46,210
+mandible، الفك.
+
+69
+00:05:49,430 --> 00:05:53,890
+ننتقل إلى الـ sinuses، ما هي الـ sinuses؟ هي عبارة عن
+
+70
+00:05:53,890 --> 00:05:59,670
+فتحات تهوية موجودة في الجمجمة، مبطنة بغشاء مخاطي،
+
+71
+00:05:59,670 --> 00:06:03,530
+على أساس أنه عندما يدخل الهواء أو الـ air
+
+72
+00:06:03,530 --> 00:06:08,450
+إلى الرئتين، يكون مُرطبًا ودافئًا، يُدفّأ، و
+
+73
+00:06:08,450 --> 00:06:15,550
+يُرطّب، لكي يدخل دافئًا إلى الرئتين. طبعًا تُخفف من
+
+74
+00:06:15,550 --> 00:06:18,950
+وزن الجمجمة، لأنها لو كانت كلها عظمًا مضغوطًا، أو
+
+75
+00:06:18,950 --> 00:06:23,650
+كانت كلها عظمًا، فستكون ثقيلة، فهي تُخفف من وزن
+
+76
+00:06:23,650 --> 00:06:28,750
+الـ skull، وتُعطي الصوت، أو الاهتزازات الخاصة
+
+77
+00:06:28,750 --> 00:06:33,460
+بالصوت. في أربعة من الـ sinuses، الـ frontal sinuses،
+
+78
+00:06:33,460 --> 00:06:38,540
+موجودة بين الحاجبين، الـ ethmoid،
+
+79
+00:06:38,540 --> 00:06:44,160
+تحتها بقليل، والـ sphenoid، أقرب إلى الأنف، والـ
+
+80
+00:06:44,160 --> 00:06:48,640
+maxillary، موجودة على عظام الخدين، الأخرى على
+
+81
+00:06:48,640 --> 00:06:55,720
+الناحية الأخرى. في عندنا الـ Hyaluron، وفي عندنا الـ
+
+82
+00:06:55,720 --> 00:06:59,380
+Fontanels، الـ Fontanels هي عبارة عن أغشية ليفية
+
+83
+00:06:59,380 --> 00:07:04,200
+تشبه فتحات موجودة في الجمجمة،
+
+84
+00:07:04,200 --> 00:07:09,840
+تسمى اليفوخ، أو النفوخ، كما يصفونه أمهاتنا
+
+85
+00:07:09,840 --> 00:07:14,400
+وجداتنا، عندما يولد الطفل، عادةً يولد بقوله نفوخ، و
+
+86
+00:07:14,400 --> 00:07:18,940
+مفتوحة، لماذا نفوخ ومفتوحة؟ يعني في فتحة بين
+
+87
+00:07:18,940 --> 00:07:26,460
+عظام الجمجمة، تسمح بمرونة، نوع من المرونة في الجمجمة، لماذا؟ لأن
+
+88
+00:07:26,460 --> 00:07:29,480
+الطفل الذي يريد الخروج من...
+
+89
+00:07:29,480 --> 00:07:34,280
+من... من بطن الأم، يحتاج للخروج من بين عظام الحوض،
+
+90
+00:07:34,510 --> 00:07:38,790
+طبعًا يحدث أنه توجد إمكانية للخروج، وتضغط هذه
+
+91
+00:07:38,790 --> 00:07:42,930
+العظام على بعضها البعض، لتسمح بمرور
+
+92
+00:07:42,930 --> 00:07:48,170
+رأس الطفل. طبعًا هذا يغلق بعد سن الخامسة عشر
+
+93
+00:07:48,170 --> 00:07:52,770
+سنة أيضًا، ليسمح لعملية نمو الدماغ ونمو
+
+94
+00:07:52,770 --> 00:07:58,690
+الجمجمة. طبعًا هو عبارة عن غشاء ليفي سميك، و
+
+95
+00:07:58,690 --> 00:08:02,810
+ليس متعظمًا، تكون له مناطق رخوة، لو وضعنا
+
+96
+00:08:02,810 --> 00:08:07,130
+يدنا على نفوخ الطفل، نجد أنه توجد فتحة، هذه الفتحة
+
+97
+00:08:07,130 --> 00:08:12,110
+العلوية، وهذه الفتحة خطيرة جدًا، لأن أي ضغط هنا، قد
+
+98
+00:08:12,110 --> 00:08:17,190
+يصل إلى هذا المكان، وقد يشكل خطرًا على
+
+99
+00:08:17,190 --> 00:08:23,930
+دماغ هذا الطفل. طبعًا المولود الجديد، عادةً يولد
+
+100
+00:08:23,930 --> 00:08:28,610
+برأس... رأس... رأسه مثل المخروط، لماذا؟
+
+101
+00:08:28,610 --> 00:08:34,450
+لأن الرأس، أثناء... خروجه من... فتحة...
+
+102
+00:08:34,450 --> 00:08:37,770
+أو من عظام الحوض، يحدث ضغط، فيحدث تراكب، أو
+
+103
+00:08:37,770 --> 00:08:41,710
+انضغاط لهذه العظام، وذلك يسمح بمرور
+
+104
+00:08:41,710 --> 00:08:46,910
+الرأس بشكل مخروطي. والصورة هنا
+
+105
+00:08:46,910 --> 00:08:51,330
+توضح، وتُظهر لنا... تُظهر لنا أين هذه... هذه
+
+106
+00:08:51,330 --> 00:08:55,170
+fontanelles، التي يحدث خلالها نمو الجمجمة،
+
+107
+00:08:55,170 --> 00:08:58,910
+وفي نفس الوقت يحدث التئام، و التَخاطم، بعد
+
+108
+00:08:58,910 --> 00:09:06,590
+نضج عظام الجمجمة. الـ sutures هي
+
+109
+00:09:06,590 --> 00:09:12,850
+مناطق ليفية غير متحركة. عندما ندرس المفاصل،
+
+110
+00:09:12,850 --> 00:09:16,370
+نجد نوعًا من أنواع المفاصل، هي غير متحركة، وهي
+
+111
+00:09:16,370 --> 00:09:21,150
+المفاصل الليفية. هي موجودة، كانت توجد فراغات بين
+
+112
+00:09:21,150 --> 00:09:24,270
+العظام، لأنها مجموعة من العظام ملتحمة،
+
+113
+00:09:24,270 --> 00:09:29,070
+تلتحم بعد سن معينة، وتصبح نسيج ضام ليفي كثيف،
+
+114
+00:09:29,070 --> 00:09:35,270
+يشبه التخاطم في شكله، ويثبت العظام،
+
+115
+00:09:35,270 --> 00:09:41,230
+بشكلٍ ثابت معًا. في منطقة التخاطم، كل الجمجمة
+
+116
+00:09:41,230 --> 00:09:45,170
+تسمح للجمجمة بالنمو والتمدد خلال
+
+117
+00:09:45,170 --> 00:09:48,550
+الطفولة. لكي يكبر الرأس، بالعربية يعني، في النهاية لو
+
+118
+00:09:48,550 --> 00:09:51,430
+وُلد الرأس، لو تشكل الرأس بنفس الحجم الذي هو
+
+119
+00:09:51,430 --> 00:09:56,050
+موجود عليه عند البلوغ، ستكون هذه مشكلة كبيرة
+
+120
+00:09:56,050 --> 00:09:59,710
+جداً في عملية الولادة للطفل، فمن المؤكد أنه يجب
+
+121
+00:09:59,710 --> 00:10:04,930
+أن يسمح لعملية بناء العظام، وزيادة حجم الرأس، حتى
+
+122
+00:10:04,930 --> 00:10:08,430
+يتناسب مع زيادة حجم الدماغ، لأن الدماغ أيضًا ينمو.
+
+123
+00:10:08,730 --> 00:10:12,470
+بعبارة أخرى، عندما يتوقف نمو الجمجمة،
+
+124
+00:10:12,470 --> 00:10:16,810
+تلتحم وتندمل التخاطمات، تصبح كما
+
+125
+00:10:16,810 --> 00:10:24,410
+نراها في الشكل، عبارة عن خطوط طبيعية،
+
+126
+00:10:24,410 --> 00:10:30,310
+تلتحم فيها العظام، كما نراها بهذا الشكل.
+
+127
+00:10:33,870 --> 00:10:37,050
+طيب، ما وظيفة العمود الفقري؟ نحن
+
+128
+00:10:37,050 --> 00:10:42,010
+انتهينا من جزء الجمجمة، ننتقل إلى العمود الفقري.
+
+129
+00:10:42,010 --> 00:10:46,610
+طيب، ما وظيفته؟ أولًا، يوجد فيه دعم،  لا بد أن نكون...
+
+130
+00:10:46,610 --> 00:10:51,070
+يجب أن نقف، نحن مثلاً
+
+131
+00:10:51,070 --> 00:10:57,040
+كما أنا واقفة هنا، أنا أقف على ماذا؟ أقف على رجليّ،
+
+132
+00:10:57,040 --> 00:11:01,320
+لكن هذا الوزن، الذي يأتي من الرأس إلى القدمين،
+
+133
+00:11:01,320 --> 00:11:05,280
+ينتقل عن طريق ماذا؟ عن طريق الجمجمة، يأتي وزن الجمجمة
+
+134
+00:11:05,280 --> 00:11:11,470
+وينزل على الرقبة، ومن الرقبة ينتقل إلى... يُوزّع
+
+135
+00:11:11,470 --> 00:11:14,830
+على الكتفين، وينزل على الظهر، على العمود الفقري،
+
+136
+00:11:14,830 --> 00:11:19,090
+ويتوزع عن طريق عظام الحوض، وينزل عن طريق عظمي الورك،
+
+137
+00:11:19,090 --> 00:11:23,790
+حتى يصل إلى الأرض عن طريق القدمين، فأنا عندما أقف،
+
+138
+00:11:23,790 --> 00:11:29,070
+أقف على ماذا؟ أقف على الأطراف السفلية، أنا عمليًا أقف
+
+139
+00:11:29,070 --> 00:11:33,270
+على الأطراف السفلية، لكن هذا الوزن،
+
+140
+00:11:33,270 --> 00:11:37,890
+يتوزع عن طريق الحوض من أعلى إلى أسفل. طبعًا، الحماية
+
+141
+00:11:37,890 --> 00:11:40,530
+للحبل الشوكي، هذه الحماية، كما
+
+142
+00:11:40,530 --> 00:11:43,790
+الجمجمة تُحمي الدماغ، الحبل الشوكي،
+
+143
+00:11:43,790 --> 00:11:48,750
+أيضًا، الموجود بداخله يحتاج إلى حماية من
+
+144
+00:11:48,750 --> 00:11:52,590
+ماذا؟ من العظام الموجودة، لأنه يوجد لدينا مجموعة من
+
+145
+00:11:52,590 --> 00:11:56,770
+الـ... يوجد لدينا النخاع الشوكي، والـ spinal
+
+146
+00:11:56,770 --> 00:12:02,750
+nerves، التي تخرج لتغذي العضلات، وتساعد على
+
+147
+00:12:02,750 --> 00:12:08,250
+الحركة، التي تُمكّن من الحركة أيضًا. عندما يكون لدينا
+
+148
+00:12:08,250 --> 00:12:12,950
+العمود الفقري ملتحمًا، فالحركة ستكون صعبة، فهو
+
+149
+00:12:12,950 --> 00:12:18,250
+وجود الحبل الشوكي على شكل حلقات، الفقرات،
+
+150
+00:12:18,250 --> 00:12:22,670
+على شكل حلقات، أو العمود الفقري على شكل حلقاته،
+
+151
+00:12:22,670 --> 00:12:27,130
+بين كل فقرتين، يوجد لدينا غضروف، يسمح هذا
+
+152
+00:12:27,130 --> 00:12:30,690
+الحركة، فأنا أستطيع الانحناء، أستطيع رفع رأسي، أستطيع الميل
+
+153
+00:12:30,690 --> 00:12:34,590
+إلى اليمين، الميل إلى اليسار، رفع رأسي لأعلى، لأسفل، وهكذا،
+
+154
+00:12:34,590 --> 00:12:40,100
+للاتجاهين، أو الاثنين، الجذع، وأرفعه أيضًا، نحن لدينا
+
+155
+00:12:40,100 --> 00:12:44,240
+عضلات، هذه العضلات هي التي تُشكّل
+
+156
+00:12:44,240 --> 00:12:47,640
+الحركة. العظام هي الرافعات،
+
+157
+00:12:47,640 --> 00:12:52,580
+يكون لديّ مجال أن يكون لديّ مواقع التصاق
+
+158
+00:12:52,580 --> 00:12:56,560
+للعضلات، توجد عضلات ملتصقة بالرأس،
+
+159
+00:12:56,560 --> 00:12:59,660
+بالرقبة، بالأطراف العلوية، والصدر، كلها
+
+160
+00:12:59,660 --> 00:13:04,360
+تكون موجودة، أو معظمها، وهي مواقع التصاق على
+
+161
+00:13:04,360 --> 00:13:10,230
+العمود الفقري. طبعًا، بالنسبة لعدد العظام،
+
+162
+00:13:10,230 --> 00:13:16,990
+فهو 33 عظمة في البالغ، مقسمة إلى خمس فئات.
+
+163
+00:13:16,990 --> 00:13:20,810
+هذه الفئات الخمس هي: الفقرات العنقية،
+
+164
+00:13:20,810 --> 00:13:27,170
+سبع في منطقة الرقبة، اثنتا عشرة في
+
+165
+00:13:27,170 --> 00:13:33,650
+المنطقة الصدرية، خمس في أسفل
+
+166
+00:13:33,650 --> 00:13:37,570
+الظهر، ما يسمى بالفقرات القطنية، وهناك خمس
+
+167
+00:13:37,570 --> 00:13:41,450
+عظم ملتحمة في العجز، كما نراها بالرسم هنا.
+
+168
+00:13:41,450 --> 00:13:48,460
+الفقرات العجزية خمس، لكنها ملتحمة معًا، ليست
+
+169
+00:13:48,460 --> 00:13:52,380
+متحركة، أسفل الفقرات القطنية، ومتصلة
+
+170
+00:13:52,380 --> 00:13:57,640
+بعظمة العصعص، أو الـ coccyx، وهي عظمة
+
+171
+00:13:57,640 --> 00:14:05,380
+الذيل، عظمة الذيل هذه، هي التي تبقى بعد أن نقول إلى
+
+172
+00:14:05,380 --> 00:14:10,620
+التراب، هي التي يُقال منها خلق، أو إعادة خلق،
+
+173
+00:14:10,620 --> 00:14:13,940
+لل
+
+223
+00:18:22,170 --> 00:18:27,270
+وفي بتتميز في أنها ال
+
+224
+00:18:29,630 --> 00:18:35,970
+الاطلس it means أنها ال spinal process فيها pivot
+
+225
+00:18:35,970 --> 00:18:41,690
+يعني زي شوكة عامل اللي هو فرعين وفي أن ال seven
+
+226
+00:18:41,690 --> 00:18:45,970
+cervical vertebra هي landmark تكون لو احنا اتحسسنا
+
+227
+00:18:45,970 --> 00:18:49,970
+في منطقة أسفل الرقبة بنلاقيها bears
+
+228
+00:18:52,260 --> 00:18:55,460
+ال spinous process تبعها هذه خواص تقريبا ال
+
+229
+00:18:55,460 --> 00:19:02,400
+cervical أو مختصر لخواص ال cervical vertebra
+
+230
+00:19:05,660 --> 00:19:09,820
+الـ thoracic vertebra فهي vertebra تقليدية لكن الـ
+
+231
+00:19:09,820 --> 00:19:14,280
+spinous process فيها أطول شوية وموجود فيها facets
+
+232
+00:19:14,280 --> 00:19:20,240
+للأضلاع، المعنى أن ال ribs هتلتقي أو الرؤوس بتيجي
+
+233
+00:19:20,240 --> 00:19:26,320
+تلتقي فيها في منطقة في منطقة التهارب فهذه بس من
+
+234
+00:19:26,320 --> 00:19:29,660
+مميزاتها أن لها long spinous process وفيها rib
+
+235
+00:19:29,660 --> 00:19:33,420
+facets أما ال lumbar فهي أكبر واحدة وأوسع واحدة
+
+236
+00:19:33,420 --> 00:19:40,630
+لها short أول شيء Large body thick تتحمل ضغط فيها
+
+237
+00:19:40,630 --> 00:19:44,750
+short spinous process موجود هي ليش أكبر واحدة
+
+238
+00:19:44,750 --> 00:19:50,050
+لأنها هي التي تحمل الضغط كل ما فوقها من الجذع يعني
+
+239
+00:19:50,050 --> 00:19:54,950
+كل وزن ال trunk وال upper limbs هيكون موجود على هذه
+
+240
+00:19:54,950 --> 00:20:02,620
+المنطقة أما ال sacrum فهي عبارة عن  fusion لخمسة
+
+241
+00:20:02,620 --> 00:20:08,340
+من ال vertebra  فيها  medial sacral crest
+
+242
+00:20:08,340 --> 00:20:12,460
+وعندنا posterior sacral foramina وال posterior wall of
+
+243
+00:20:12,460 --> 00:20:17,580
+the pelvic cavity هي بتكون مكونة من اللي هي ال
+
+244
+00:20:17,580 --> 00:20:22,480
+sacrum وفي ال sacral promontory زي ما هو موضح عندنا
+
+245
+00:20:22,480 --> 00:20:27,760
+بالشكل الموجود أما الكوكسيس فهي قلنا الـ tail bone
+
+246
+00:20:27,760 --> 00:20:33,260
+هي عبارة عن four fused vertebra هذه هي قلنا العظمة
+
+247
+00:20:33,260 --> 00:20:40,140
+التي تبقى ويعاد بها خلق الإنسان أو الحيوان مرة
+
+248
+00:20:42,370 --> 00:20:48,330
+طبعا أكثر skeleton في through the life بيكون أول
+
+249
+00:20:48,330 --> 00:20:51,990
+ما بيبدأ ما بتبدأ ال curvature هذه بتبدأ في عينة
+
+250
+00:20:51,990 --> 00:20:57,510
+primary curvature بتبدأ في جنين شكله C بشكل
+
+251
+00:20:57,510 --> 00:21:03,050
+حرف ال C بيبدأ يتشكل مع نموه فيبقى عندنا ال sacral
+
+252
+00:21:03,050 --> 00:21:09,200
+وثم ال curvature هذه primary و concave
+
+253
+00:21:09,200 --> 00:21:12,160
+posteriorly أما ال secondary curvature زي ال
+
+254
+00:21:12,160 --> 00:21:16,980
+cervical و ال lumbar بيبدأ تشكيلهم كلما تطورنا في
+
+255
+00:21:16,980 --> 00:21:20,580
+النمو طبعا ال cervical curvature بيبدأ من لحظة
+
+256
+00:21:20,580 --> 00:21:24,960
+أول ما بيبدأ الطفل يرفع رأسه وهو في ال point
+
+257
+00:21:24,960 --> 00:21:28,800
+position فهو بيبدأ يشكل عنده هذا ال curve لما
+
+258
+00:21:28,800 --> 00:21:33,140
+بيمشي تبدأ تزيد ال curve لما يظهر بمظهرها الذي
+
+259
+00:21:33,140 --> 00:21:38,850
+احنا بنشوفه في ال adult طبعا هي كل وظيفتها
+
+260
+00:21:38,850 --> 00:21:45,690
+أنها تعمل redistribution لل weight من ال upper
+
+261
+00:21:45,690 --> 00:21:51,310
+body إلى ال lower limbs طبعا في عندنا three main curves
+
+262
+00:21:57,460 --> 00:22:01,680
+Kyphosis هو عبارة عن exaggeration أو زيادة في
+
+263
+00:22:01,680 --> 00:22:07,140
+التقوس  ال curvature directly posteriorly بتسميها
+
+264
+00:22:07,140 --> 00:22:11,940
+hunchback أو round back أما ال lordosis فهي
+
+265
+00:22:11,940 --> 00:22:16,220
+زيادة ال lordosis بيسموها sway back بيكون فيه زيادة في
+
+266
+00:22:16,220 --> 00:22:21,040
+ال lumbar lordosis بيصير المظهر أنه في عندنا
+
+267
+00:22:21,040 --> 00:22:25,080
+big belly زي المرأة الحامل وفي عندنا big buttocks
+
+268
+00:22:25,080 --> 00:22:30,520
+في الخلف يعني من قدام فيه كرش ومن خلف أما الـ
+
+269
+00:22:30,520 --> 00:22:33,240
+scoliosis فهي abnormal lateral curvature هذه
+
+270
+00:22:33,240 --> 00:22:37,780
+نشوفها في الـ posterior view بتطلع عندنا شكل ال
+
+271
+00:22:37,780 --> 00:22:43,660
+vertebral column مائل laterally فهذه بتكون عبارة
+
+272
+00:22:43,660 --> 00:22:47,950
+عن أحيانا بتكون structural أو postural، الـ
+
+273
+00:22:47,950 --> 00:22:51,590
+postural بتكون ممكن تعديلها بال exercise، أما ال
+
+274
+00:22:51,590 --> 00:22:55,530
+structural فهذه بتحتاج تدخلات أخرى وهو ال
+
+275
+00:22:55,530 --> 00:22:58,510
+scoliosis the most common spinal curvature هي
+
+276
+00:22:58,510 --> 00:23:03,230
+بتنتج عن ايش؟ هي بتنتج عن مشكلة أثناء development
+
+277
+00:23:03,230 --> 00:23:08,370
+لل vertebral arch في حتى فترة ال infancy أو بعد
+
+278
+00:23:10,790 --> 00:23:20,710
+هذه صورة توضيحية للـ  .. الـ ..  ال thoracic cage
+
+279
+00:23:20,710 --> 00:23:27,270
+القفص الصدري هو عبارة عن القفص الصدري، إيش وظيفة القفص
+
+280
+00:23:27,270 --> 00:23:33,410
+الصدري؟ أنه يحمي ال vital organs زي ال heart و ال
+
+281
+00:23:33,410 --> 00:23:38,520
+lungs، the trachea و ال oesophagus طبعا هدولة بدهم
+
+282
+00:23:38,520 --> 00:23:42,060
+بيحتاجوا protection طيب ال thoracic cage من ايش
+
+283
+00:23:42,060 --> 00:23:46,040
+بتكون؟ بتكون من ال ribs، ال sternum ومن ال
+
+284
+00:23:46,040 --> 00:23:50,580
+thoracic vertebra طبعا في أن عضلات التنفس بتكون
+
+285
+00:23:50,580 --> 00:23:59,400
+كلها مثبتة في هذا الـ .. في ال rib cage وكمان في أن
+
+286
+00:23:59,400 --> 00:24:02,700
+عضلات اللي هي ال pectoral girdle و ال chest muscles
+
+287
+00:24:02,700 --> 00:24:06,120
+و ال shoulder و ال back musculatures دائما بتكون
+
+288
+00:24:06,120 --> 00:24:10,300
+involved في ال respiration طبعا هذا شكله فيه هنا
+
+289
+00:24:10,300 --> 00:24:15,870
+عدد من واحد إلى سبعة من ال ribs بنسميهم true ribs
+
+290
+00:24:15,870 --> 00:24:20,250
+وفي عندنا ال false ribs لأنها ليست true ribs
+
+291
+00:24:20,250 --> 00:24:24,410
+هلقيتها هنقول ليش لأن هدول كل واحدة من ال ribs عن
+
+292
+00:24:24,410 --> 00:24:28,630
+طريق ال costal cartilage بتكون لها attachment مع
+
+293
+00:24:28,630 --> 00:24:32,730
+ال sternum أما ال first rib اللي هم من ثمانية تقريبا
+
+294
+00:24:32,730 --> 00:24:37,030
+إلى 12 في منهم ال 11 و 12 هدول floating ما لهمش أي
+
+295
+00:24:37,030 --> 00:24:40,770
+attachment مع أي شيء وهم ليسوا coastal cartilage أما
+
+296
+00:24:40,770 --> 00:24:47,090
+من ثمانية إلى عشرة فهم كلهم مع بعض attached في one
+
+297
+00:24:47,090 --> 00:24:51,510
+attachment أو coastal cartilage واحد في ال sternum
+
+298
+00:24:55,430 --> 00:24:59,490
+زي ما هنا شرحنا على الرسمة بنعيد الكلام أما ال
+
+299
+00:24:59,490 --> 00:25:04,170
+floating ribs فهي ليست ما عندهاش أي connection مع
+
+300
+00:25:04,170 --> 00:25:10,510
+ال sternum هي floating عائمة وهذا
+
+301
+00:25:10,510 --> 00:25:20,880
+شكل ال rib كل rib بيكون لها تلتقي مع الـ sternum و
+
+302
+00:25:20,880 --> 00:25:25,800
+كمان من الناحية الأخرى تلتقي مع الـ .. من الخلف مع
+
+303
+00:25:25,800 --> 00:25:32,400
+ال vertebra وبهيك احنا بنكون خلصنا حديثنا عن ال
+
+304
+00:25:32,400 --> 00:25:35,880
+axial skeleton والمحاضرة القادمة تكون عن ال
+
+305
+00:25:35,880 --> 00:25:39,020
+appendicular skeleton، يعطيكم العافية
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..559b0e386bde81677ea5fc715f1891692b3365a8
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs_postprocess.srt
@@ -0,0 +1,1220 @@
+1
+00:00:04,980 --> 00:00:09,940
+بسم الله الرحمن الرحيم طلابنا الأعزاء اليوم
+
+2
+00:00:09,940 --> 00:00:14,260
+استكمالة لمحادرات skeletal system الجزء التاني من
+
+3
+00:00:14,260 --> 00:00:17,680
+المحادرة هنتكلم فيها عن ال axial skeleton اللي هو
+
+4
+00:00:17,680 --> 00:00:25,390
+بيتمثل بال head، ال trunkand the vertebral column
+
+5
+00:00:25,390 --> 00:00:29,790
+ان شاء الله تكون الصور التوضيحية اللى موجودة معنا
+
+6
+00:00:29,790 --> 00:00:33,690
+فى ال presentation بتساعد فى الشرح هي اضطرد انه
+
+7
+00:00:33,690 --> 00:00:36,770
+كان يكون معانا ال skeleton اليوم بس مع صعوبة
+
+8
+00:00:36,770 --> 00:00:39,450
+التنقل انا قولت الصور ان شاء الله تكون التوضيحية
+
+9
+00:00:39,450 --> 00:00:44,980
+بتعطينا فكرة عن ال skeletonال Axial skeleton طبيعي
+
+10
+00:00:44,980 --> 00:00:48,320
+بتكون من ال head, the neck and the trunk، ال trunk
+
+11
+00:00:48,320 --> 00:00:54,860
+طبعا اللي هو بيشمل الجدع، ما بنسمي احنا الجزاء،
+
+12
+00:00:54,860 --> 00:00:59,520
+اما ال perpendicular system او skeleton فهو عبارة
+
+13
+00:00:59,520 --> 00:01:03,250
+عن ال upper limbs، ال lower limbsالـ pictorial
+
+14
+00:01:03,250 --> 00:01:08,170
+girdle and pelvic girdle طبعا المحاضرة اللي جاي ان
+
+15
+00:01:08,170 --> 00:01:10,910
+شاء الله هتكون على pedicular system اليوم هنتكلم
+
+16
+00:01:10,910 --> 00:01:16,070
+عن ال axial skeleton ال axial skeleton حسب ما هو
+
+17
+00:01:16,070 --> 00:01:22,950
+موضح بالرسم في ان ال headبكل العظام المكوّنة
+
+18
+00:01:22,950 --> 00:01:28,670
+لـSkull في عندنا الـNeck وفي عندنا thoracic cage
+
+19
+00:01:28,670 --> 00:01:33,910
+زي ما هو مضحن بالرسم و ال vertebral column as well
+
+20
+00:01:33,910 --> 00:01:38,850
+هنتكلم عنهم بالتفصيل ان شاء الله طبعا ال skull هي
+
+21
+00:01:38,850 --> 00:01:43,390
+عبارة عن الجمجمة اللي وظفتها اللي بتحتوي عن تمان
+
+22
+00:01:43,390 --> 00:01:49,650
+عظام تمان عظام هذه وظفتها انها تحيط و تغلق على ال
+
+23
+00:01:49,650 --> 00:01:54,290
+brainطبعا في ان ال face bone ال face bone هي دي
+
+24
+00:01:54,290 --> 00:02:00,350
+اتناشر عضمة وزفتها انها بتعمل passengers ل
+
+25
+00:02:00,350 --> 00:02:04,650
+digestive و respiratory system بتعملنا entrance
+
+26
+00:02:04,650 --> 00:02:09,990
+وكمان بتعطيني مكان حتى ال facial muscle اللي هي
+
+27
+00:02:09,990 --> 00:02:15,630
+بتأثر على ال facial expressions بتكون attached في
+
+28
+00:02:15,630 --> 00:02:22,210
+هذه ال .. ال boneطبعا بالنسبة لـ cranium احنا كلنا
+
+29
+00:02:22,210 --> 00:02:26,410
+حافظين ان في عندنا عضمات رئيسية و كبيرة زي ال
+
+30
+00:02:26,410 --> 00:02:32,230
+frontal bone زي ما هم وضحها بهذا الشكل هي عضمة
+
+31
+00:02:32,230 --> 00:02:38,030
+كبيرة اللي هي عضمة الجبهةو في عندنا ال parietal في
+
+32
+00:02:38,030 --> 00:02:41,230
+عندنا عضمتين هي ال frontal عضمة واحدة لكن في عندنا
+
+33
+00:02:41,230 --> 00:02:47,490
+عضمتين موجودين في جناب الجنجمة هي ال parietal و
+
+34
+00:02:47,490 --> 00:02:53,070
+تحتهم على طول بيكون في عندنا ال occipital في خلفية
+
+35
+00:02:53,070 --> 00:02:58,930
+الرأس عضمة واحدةوكمان هنا ال temporal اللي هي فوق
+
+36
+00:02:58,930 --> 00:03:03,850
+الأذن ومحيط الأذن في عنا عضلتين على الناحية تانية
+
+37
+00:03:03,850 --> 00:03:07,290
+طبعا احنا من ال 80 cranial bones احنا بتكلم عن
+
+38
+00:03:07,290 --> 00:03:12,910
+الرأسيات ان في انا اكتر من هم عددهم تمانية لأنه في
+
+39
+00:03:12,910 --> 00:03:19,310
+pairs وفي only one boneفالشكل هنا واضح بالعضمات
+
+40
+00:03:19,310 --> 00:03:25,850
+اللي موجودة وأماكن تواجدها تماما ال skull بقل نقول
+
+41
+00:03:25,850 --> 00:03:31,190
+هي بتشكل الحماية ل ال brain وبنفس الوقت فيها
+
+42
+00:03:31,190 --> 00:03:34,790
+cavities ال cavities هذه إيش وظفتها؟
+
+43
+00:03:37,430 --> 00:03:40,570
+لو ال brain أو ال cranial cavity هي أكبر cavity
+
+44
+00:03:40,570 --> 00:03:44,830
+تقريبا موجودة في هذه المنطقة بتسكر و بتعمل
+
+45
+00:03:44,830 --> 00:03:48,870
+cushions لل brain بتحمي ال brain و بقى كمان من
+
+46
+00:03:48,870 --> 00:03:52,590
+خلال ال meninges اللي موجودة بتشكل حماية أكبر و
+
+47
+00:03:52,590 --> 00:03:56,550
+بتعمل shock absorption كمان لأي صدمة لإن احنا برا
+
+48
+00:03:56,550 --> 00:04:01,290
+في ال brain جزء حساس من جسم الإنسان و هو عبارة عن
+
+49
+00:04:01,290 --> 00:04:04,950
+ال control تبع الجسم كله فبالتالي بحتاج لحمية كتير
+
+50
+00:04:04,950 --> 00:04:09,050
+كبيرةلكن مش مكوّن من عدة إضام مش عضمة واحدة لإنه
+
+51
+00:04:09,050 --> 00:04:12,390
+هذه الإضام، مجموعة الإضام هذه مع الفتحات اللي
+
+52
+00:04:12,390 --> 00:04:17,690
+بينها بتسمح لانمو، ايضا في انفتاحات تانية لإن
+
+53
+00:04:17,690 --> 00:04:22,770
+العين، لإن العيون موجودة برضه في فتحات نسميها ال
+
+54
+00:04:22,770 --> 00:04:27,010
+orbits، فينا ال oral cavity عشان اللي هي بتمثل ال
+
+55
+00:04:27,010 --> 00:04:30,150
+mouth عشان نقدر ناكل، فينا ال nasal cavity و ال
+
+56
+00:04:30,150 --> 00:04:34,090
+paranasal sinuses عشان ال
+
+57
+00:04:35,890 --> 00:04:42,270
+تساعد على عملية التنفس والـ Paranasal Sinuses هذه
+
+58
+00:04:42,270 --> 00:04:50,210
+عشان تساعد هتزات الصوت لما احنا مصدر الأصل طبعا
+
+59
+00:04:50,210 --> 00:04:53,510
+هنا العضمات الصغيرة هذه موضحة بالرسم زي
+
+60
+00:04:53,510 --> 00:04:57,870
+الـSphenoid و
+
+61
+00:04:57,870 --> 00:05:03,430
+الـ Ethmoidوالـ maxillary هنا عظمة الوجه الان فانا
+
+62
+00:05:03,430 --> 00:05:06,230
+قاعدة بتكلم عن ال facial skeleton ال maxillary
+
+63
+00:05:06,230 --> 00:05:12,910
+اللي هي عظمة الفك العلوية ال ال palatine فما هي
+
+64
+00:05:12,910 --> 00:05:19,470
+موضحة بالرسم فوق الفك تحت ال الان is a genetics
+
+65
+00:05:19,470 --> 00:05:26,730
+اللي هي عبارة عن عظام الخد بخدودو اللى كرمل تحت
+
+66
+00:05:26,730 --> 00:05:35,550
+العين و نزل حوالين الناض و الفومر طبعا
+
+67
+00:05:35,550 --> 00:05:44,170
+فى كتراجه على حسب الرسم العظام كلها عظام الوجه ال
+
+68
+00:05:44,170 --> 00:05:46,210
+mandible الفك
+
+69
+00:05:49,430 --> 00:05:53,890
+نتروح للـ sinuses إيش هي ال sinuses؟ هي عبارة عن
+
+70
+00:05:53,890 --> 00:05:59,670
+فتحات تهوية موجودة في ال skull lining with mucous
+
+71
+00:05:59,670 --> 00:06:03,530
+membrane على أساس أنه لما يدخل الهواء أو ال air
+
+72
+00:06:03,530 --> 00:06:08,450
+إلى ال lungs يبقى humidified and warm بتدفي و
+
+73
+00:06:08,450 --> 00:06:15,550
+بترتبه عشان يدخل الجاف إلى الرئتينطبعا بتخلي ال
+
+74
+00:06:15,550 --> 00:06:18,950
+skull خفيفة لأنها لو كانت كلها compact bone او
+
+75
+00:06:18,950 --> 00:06:23,650
+كانت كلها bone فهذه بتكون تقيلة فهي بتخفف من وزن
+
+76
+00:06:23,650 --> 00:06:28,750
+ال skull و بتعطيني الصوت او الاهتزازات الخاصة
+
+77
+00:06:28,750 --> 00:06:33,460
+بالصوتفينا أربع من الـ sinuses ال frontal sinuses
+
+78
+00:06:33,460 --> 00:06:38,540
+موجودة بين ال two pores اللي هو الحواجب ال ethmoid
+
+79
+00:06:38,540 --> 00:06:44,160
+تحت منها شوية و ال sphenoid أقرب إلى الانف و ال
+
+80
+00:06:44,160 --> 00:06:48,640
+auxiliary موجودة على رؤوس الخدود التانية على
+
+81
+00:06:48,640 --> 00:06:55,720
+الناحية التانيةفي عندنا الـ Hyaluron وفي عندنا الـ
+
+82
+00:06:55,720 --> 00:06:59,380
+Fontanels الـ Fontanels هي عبارة عن Vibrous
+
+83
+00:06:59,380 --> 00:07:04,200
+Membrane بيعمل زي فتحات موجودة في الـ skull
+
+84
+00:07:04,200 --> 00:07:09,840
+بتسميها اليفوخ أو النفوخ على زي ما بيوصفوه أمهاتنا
+
+85
+00:07:09,840 --> 00:07:14,400
+وجداتنا لما بيولد الطفل عادة بنولد بقوله نفوخ و
+
+86
+00:07:14,400 --> 00:07:18,940
+مفتوحليش يعني نفوخ و مفتوح؟ يعني في فتحة ما بين
+
+87
+00:07:18,940 --> 00:07:26,460
+الـ skull bones تسمح لمرونة، نوع من المرونة في الـ
+
+88
+00:07:26,460 --> 00:07:29,480
+skull ليش؟ لأن هو هذا الطفل اللي ما بده يخرج من ..
+
+89
+00:07:29,480 --> 00:07:34,280
+من .. من بطن الأم بيكون بده يخرج من بين عظام الحُر
+
+90
+00:07:34,510 --> 00:07:38,790
+طبعا بيصير أنه فيه إمكانية خروج و بتنضغط هذه
+
+91
+00:07:38,790 --> 00:07:42,930
+العضام على بعضها بيصيرلها كلها عشان تسمح بالبسج ل
+
+92
+00:07:42,930 --> 00:07:48,170
+ال head of the baby طبعا هذا بتسكر بعد سن خمس عشر
+
+93
+00:07:48,170 --> 00:07:52,770
+سنة كمان عشان يسمح لعملية نمو ل brain و نمو لل
+
+94
+00:07:52,770 --> 00:07:58,690
+skull طبعا هو عبارة عن thickened fibrous membraneو
+
+95
+00:07:58,690 --> 00:08:02,810
+it is not ossified بيبقى له soft spots لو حطينا
+
+96
+00:08:02,810 --> 00:08:07,130
+ايدنا على نفوخ ال baby بنلاقي انه في فتحة هذه فتحة
+
+97
+00:08:07,130 --> 00:08:12,110
+الي فوق وهذه الفتحة خطيرة جدا لأنه اي قلق هدا هدا
+
+98
+00:08:12,110 --> 00:08:17,190
+حد ممكن توصل لهذا المكان ممكن تشكل خطورة على ال
+
+99
+00:08:17,190 --> 00:08:23,930
+brain تبع هذا الطفلطبعا الـ newborn عادة بيولد
+
+100
+00:08:23,930 --> 00:08:28,610
+بشكل ال .. ال .. ال head عنده زي المخروط كده ليش؟
+
+101
+00:08:28,610 --> 00:08:34,450
+لأنه ال head ساعت ال .. خروجه من ال .. فتحة ال ..
+
+102
+00:08:34,450 --> 00:08:37,770
+او من عظمات الحواب تبين ضغط تبصير overlapping أو
+
+103
+00:08:37,770 --> 00:08:41,710
+collapse لهذه الأنظام عسى انه تسمح في البسش فبطلع
+
+104
+00:08:41,710 --> 00:08:46,910
+الرأس عامل زي ال .. المخروط كون شانوالصورة هنا
+
+105
+00:08:46,910 --> 00:08:51,330
+بتوضح هي بتودينا .. بتودينا وين هذه ال .. ال
+
+106
+00:08:51,330 --> 00:08:55,170
+fontanelles اللي خلالها بيصير عملية نمول ال skull
+
+107
+00:08:55,170 --> 00:08:58,910
+و بنفس الوقت بيصير enclose و sutures بعد ال
+
+108
+00:08:58,910 --> 00:09:06,590
+maturation ل ال bones of the skull ال sutures are
+
+109
+00:09:06,590 --> 00:09:12,850
+immovable fibrous zonesلما نجي ندرس عن ال joints
+
+110
+00:09:12,850 --> 00:09:16,370
+أنه في نوع من أنواع ال joints it's immovable و the
+
+111
+00:09:16,370 --> 00:09:21,150
+fibrous joints هي موجودة في موجود فرغات كانت
+
+112
+00:09:21,150 --> 00:09:24,270
+موجودة بين العضام لإن هي مجموعة من العضام ملتحمة
+
+113
+00:09:24,270 --> 00:09:29,070
+بتلتحم بعد سن بتصير dense regular connective
+
+114
+00:09:29,070 --> 00:09:35,270
+tissue عاملة زي ال suture شكلها و بتمسك ال bones
+
+115
+00:09:35,270 --> 00:09:41,230
+firmly together في منطقة ال sutureall the cranium
+
+116
+00:09:41,230 --> 00:09:45,170
+allow the cranium to grow and expand during
+
+117
+00:09:45,170 --> 00:09:48,550
+childhood عشان الراس تكبر بالعربي يعني بالأخر لو
+
+118
+00:09:48,550 --> 00:09:51,430
+انولد الراس لو انخلق الراس بنفس الحجم اللي هو
+
+119
+00:09:51,430 --> 00:09:56,050
+موجود عليه لما بنصير فيه adult دي بتكون مشكلة كتير
+
+120
+00:09:56,050 --> 00:09:59,710
+كبيرة في عملية ال delivery لل baby فأكيد أنه لازم
+
+121
+00:09:59,710 --> 00:10:04,930
+يسمح لعملية البناء للعظيم وكبر حجم الراس حتى
+
+122
+00:10:04,930 --> 00:10:08,430
+يتناسب مع كبر حجم ال brain لأن ال brain برضه ابيان
+
+123
+00:10:08,730 --> 00:10:12,470
+in other words when cranial growth has stopped the
+
+124
+00:10:12,470 --> 00:10:16,810
+suture refused and obliterated خلاص بتصير زي ما
+
+125
+00:10:16,810 --> 00:10:24,410
+احنا شايفينها بالشكل عبارة عن ستر طبيعية
+
+126
+00:10:24,410 --> 00:10:30,310
+بتلتحن فيها العضام زي ما احنا شايفينها بهذا الشكل
+
+127
+00:10:33,870 --> 00:10:37,050
+طيب إيش ال function of the vertebral column؟ احنا
+
+128
+00:10:37,050 --> 00:10:42,010
+لقيت خلصنا جزء ال skull، بنروح لل vertebral column
+
+129
+00:10:42,010 --> 00:10:46,610
+طيب إيش وظيفته؟ أول حاجة في عندنا الواد بيصير في
+
+130
+00:10:46,610 --> 00:10:51,070
+support، مانقاش، بدنا نصير .. بدنا نوقف احنا مثلا
+
+131
+00:10:51,070 --> 00:10:57,040
+زي ما أنا واقفة هناأنا وقفة على إش ووقفة على رجليا
+
+132
+00:10:57,040 --> 00:11:01,320
+لكن هال weight هذا اللي بيجي من ال head إلى القدم
+
+133
+00:11:01,320 --> 00:11:05,280
+بنتقل عن طريق إش عن طريق ال skull بيجي ال skull
+
+134
+00:11:05,280 --> 00:11:11,470
+وزنها بينزل على ال neck من ال neck بيروح علىبتوزع
+
+135
+00:11:11,470 --> 00:11:14,830
+على ال shoulder وبنزل back على ال vertebral column
+
+136
+00:11:14,830 --> 00:11:19,090
+بتوزع عن طريق أظام الحاض وبنزل عن طريق ال two hips
+
+137
+00:11:19,090 --> 00:11:23,790
+لحد يوصل للأرض عن طريق الفوتي فانا لما بدي أوقف
+
+138
+00:11:23,790 --> 00:11:29,070
+بوقف على اش بوقف على العدم عدم اش انا عمليا بوقف
+
+139
+00:11:29,070 --> 00:11:33,270
+على عدم اللي هو lower limbs لكن ال weight هذا
+
+140
+00:11:33,270 --> 00:11:37,890
+بيتوزع عن طريق الحاض من فوق لتحتطبعا الـ
+
+141
+00:11:37,890 --> 00:11:40,530
+protection للـ spinal cord هذا الـ protection زي
+
+142
+00:11:40,530 --> 00:11:43,790
+ما الـ skull بتعمل الـ protection للبرن ال spinal
+
+143
+00:11:43,790 --> 00:11:48,750
+cord كمان اللي موجود في الدهر بده ال protection من
+
+144
+00:11:48,750 --> 00:11:52,590
+أيش؟ من الأضام اللي موجودة لأنه في عندنا مجموعة من
+
+145
+00:11:52,590 --> 00:11:56,770
+ال .. في عندنا أول أشيه النخاع وفي عندنا ال spinal
+
+146
+00:11:56,770 --> 00:12:02,750
+nerves اللي بتطلع عشان تغدي العضلات و تساعد على
+
+147
+00:12:02,750 --> 00:12:08,250
+الحركة اللي بتاعة تتقدر للحركة كمانلما يكون في عنا
+
+148
+00:12:08,250 --> 00:12:12,950
+ال vertebral column fused فالحركة بتكون صعبة فهي
+
+149
+00:12:12,950 --> 00:12:18,250
+وجود spinal cord على شكل حلقة ال spinal vertebra
+
+150
+00:12:18,250 --> 00:12:22,670
+على شكل حلقات او vertebral column على شكل حلقاته
+
+151
+00:12:22,670 --> 00:12:27,130
+between in between each two في عنا disc هذا بيسمحي
+
+152
+00:12:27,130 --> 00:12:30,690
+الحركة فانا بقدر اوطي بقدر ارفع رأسي بقدر امايل
+
+153
+00:12:30,690 --> 00:12:34,590
+على اليمين امايل على الشمال ارفع رأسي فوق تحت وكده
+
+154
+00:12:34,590 --> 00:12:40,100
+للاتنين الحاضر او اتنينالجدع و ارفعه كمان احنا في
+
+155
+00:12:40,100 --> 00:12:44,240
+عندنا عضلات هذه العضلات هي اللي بدها تشكل ال
+
+156
+00:12:44,240 --> 00:12:47,640
+movement العظام هي عبارة عن ال liver الراوافع
+
+157
+00:12:47,640 --> 00:12:52,580
+بيكون في عندي مجال ان انا يكون في عندي attachments
+
+158
+00:12:52,580 --> 00:12:56,560
+على ال muscle في عندنا muscle attached to the head
+
+159
+00:12:56,560 --> 00:12:59,660
+to the neck ال upper extremity و ال thorax كلها
+
+160
+00:12:59,660 --> 00:13:04,360
+بتكون موجودة على او معظمها اللي هي attachments على
+
+161
+00:13:04,360 --> 00:13:10,230
+ال vertebral columnطبعا بالنسبة لأعداد ال bone
+
+162
+00:13:10,230 --> 00:13:16,990
+يعني 33 bone في ال adult مقسمة لخمسة categories
+
+163
+00:13:16,990 --> 00:13:20,810
+الخمسة categories هذه هي عبارة عن cervical
+
+164
+00:13:20,810 --> 00:13:27,170
+vertebra سبعة في ال neck region twelve في ال
+
+165
+00:13:27,170 --> 00:13:33,650
+vertebralفي الـthoracic region خمسة في الـlower
+
+166
+00:13:33,650 --> 00:13:37,570
+back اللي مسموها الخمسة القطنية وفيه هنا خمسة
+
+167
+00:13:37,570 --> 00:13:41,450
+fused في الـsacrum اللي احنا شايفينهم بالرسم هنا
+
+168
+00:13:41,450 --> 00:13:48,460
+الـsacral vertebra هي خمسة لكن fused togetherمش
+
+169
+00:13:48,460 --> 00:13:52,380
+mobile inferior to the lumbar vertebra وarticulate
+
+170
+00:13:52,380 --> 00:13:57,640
+with the coccygeal أو الـcoccyx هي عبارة عن عضمة
+
+171
+00:13:57,640 --> 00:14:05,380
+الديل عضمة الديل هذه هي اللي بتبقى بعد ما نقول إلى
+
+172
+00:14:05,380 --> 00:14:10,620
+التراب فهي اللي بيقود منها خلق أو إعادة الخلق
+
+173
+00:14:10,620 --> 00:14:13,940
+للأشخاص فهي العضمة الوحيدة اللي بتبقى من جسم
+
+174
+00:14:13,940 --> 00:14:21,110
+الإنسان لتبلغطبعا فيه ان في
+
+175
+00:14:21,110 --> 00:14:26,710
+ال lumber و ال cervical و ال thoracic هو العمول
+
+176
+00:14:26,710 --> 00:14:32,750
+الفقاري احنا بنسميه مش straight lineفيه curves ال
+
+177
+00:14:32,750 --> 00:14:37,750
+curves هذه بتبدأ نمو و تطور فيها من و احنا أجلنا و
+
+178
+00:14:37,750 --> 00:14:43,330
+بعدها في فترة الطفولة بتبدأ تتشكل فعينا في
+
+179
+00:14:43,330 --> 00:14:48,770
+cervical and lumbar curvature concave posteriorly
+
+180
+00:14:48,770 --> 00:14:53,050
+ال concavity او التقاعر تبعهم الى الخلف وفيه ال
+
+181
+00:14:53,050 --> 00:15:02,310
+thoracic والsacral الالتقاعر فيهم إلى الأمام فهي
+
+182
+00:15:02,310 --> 00:15:05,730
+الـ cervical and lumbar concave posteriorly أما
+
+183
+00:15:05,730 --> 00:15:10,690
+الـ thoracic and sacral convex posteriorly في
+
+184
+00:15:10,690 --> 00:15:16,550
+محددة من الخلط طبعا هذه الـcervitures إيش وظيفتها؟
+
+185
+00:15:16,550 --> 00:15:20,730
+بتعمل ك shock absorption بتزود ال mobility تبع
+
+186
+00:15:20,730 --> 00:15:27,930
+الجسم وبتحافظ على الدونةبتعطي المرونة أما تركيبة
+
+187
+00:15:27,930 --> 00:15:32,390
+ال vertebra نفسها فهي عبارة عن body اللي احنا
+
+188
+00:15:32,390 --> 00:15:40,720
+شايفينها فيه بديكلس بتوصل ل transversal processمع
+
+189
+00:15:40,720 --> 00:15:45,280
+ال body وفيه إنه حاجة اسمها Lamina وفيه إنه بستيرو
+
+190
+00:15:45,280 --> 00:15:49,180
+ال spine زي إحنا شايفينه وفيه إن الفرامين هذا اللي
+
+191
+00:15:49,180 --> 00:15:54,180
+بيفوت منه أو بيحتوي على النخاع الشوكي أو ال spinal
+
+192
+00:15:54,180 --> 00:15:57,840
+cord طبعا لما بيصير ضغط أو بيصير فيه إنه disk
+
+193
+00:15:57,840 --> 00:16:01,760
+prolapse أو بيصير ضغط على القناة الشوكية إيش
+
+194
+00:16:01,760 --> 00:16:04,640
+بيعملوا ال surgeon بيروحوا عند منطقة ال Lamina
+
+195
+00:16:04,640 --> 00:16:08,240
+وبيعملوا Laminectomy بيشيلوا اللامن هذي عشان
+
+196
+00:16:08,240 --> 00:16:14,740
+يريحوا الانخعوا يريحوا الـ spinal nerve اللي طبعا
+
+197
+00:16:14,740 --> 00:16:22,160
+هذا تقريبا شكل ال ال vertebra اللي بتكون بين each
+
+198
+00:16:22,160 --> 00:16:25,640
+two vertebra فى انه حاجة اسمها intervertebral disk
+
+199
+00:16:25,640 --> 00:16:31,120
+ال structure و ال function ال function يقول ال
+
+200
+00:16:31,120 --> 00:16:34,600
+disk بتكون من حاجة اسمها انهيراسوبروسس و
+
+201
+00:16:34,600 --> 00:16:39,770
+نوكياسبالبوسس هو عبارة عن مادة cartilageوفيها
+
+202
+00:16:39,770 --> 00:16:45,050
+نوعها بتعمل ك shock absorption تنفس الصدمات على ال
+
+203
+00:16:45,050 --> 00:16:51,930
+back عشان تخفف من ال risk لل fracturesطب احنا
+
+204
+00:16:51,930 --> 00:16:56,410
+بنوصف يعني ايش الفرق بين ال cervical و بين ال
+
+205
+00:16:56,410 --> 00:17:00,550
+thoracic و بين ال lumbar ال cervical هي بتحمل بس
+
+206
+00:17:00,550 --> 00:17:05,470
+ال head فهي من ناحية biomechanics الوزن اللي
+
+207
+00:17:05,470 --> 00:17:10,270
+بتحمله cervical و vertebra طبعا بتحمل بس وزن الرأس
+
+208
+00:17:10,840 --> 00:17:16,280
+الـ thoracic بتحمل وزن الرأس مع ال neck مع جزء من
+
+209
+00:17:16,280 --> 00:17:20,200
+ال trunk أما ال lumbar فبتحمل كل هدول مع ال belfry
+
+210
+00:17:20,200 --> 00:17:25,360
+الجردل مع ال thoracic أو ال pectoral girdle و ال
+
+211
+00:17:25,360 --> 00:17:30,720
+upper limb فالطبيعي احنا يتدرج حجم هذه ال vertebra
+
+212
+00:17:30,720 --> 00:17:35,520
+من أعلى إلى أسفل في اتجاه الكبرإيش؟ لأنه لو
+
+213
+00:17:35,520 --> 00:17:39,120
+تتكلمنا عن الضغط اللي بتتحمله هذه ال vertebra كل
+
+214
+00:17:39,120 --> 00:17:42,580
+ما كنا في الأسفل هتحمل وزن أكتر فهيتوزع الوزن على
+
+215
+00:17:42,580 --> 00:17:46,520
+ال area فمنطق أنها تكون أكبر عشان يكون الضغط عليها
+
+216
+00:17:46,520 --> 00:17:51,420
+أقل أو ال stress اللي هتتحمله أقل طبعا ال Atlas و
+
+217
+00:17:51,420 --> 00:17:55,560
+ال axis في ال cervical vertebra هدولة لها خصوصية
+
+218
+00:17:55,560 --> 00:18:00,080
+ال Atlas هي العضمة اللي بتيجي عليها يقعد عليها ال
+
+219
+00:18:00,080 --> 00:18:05,450
+head فهي support the headأما ال axis فهي عضلة إلها
+
+220
+00:18:05,450 --> 00:18:11,590
+زي النحور عشان تساعد على حركة الرأس إلى اليمين إلى
+
+221
+00:18:11,590 --> 00:18:16,550
+الوسار فهذه بتساعدنا على الحركة في إنها طبعا ال
+
+222
+00:18:16,550 --> 00:18:22,170
+transverse foramen اللي يفوت منه ال spinal cord
+
+223
+00:18:22,170 --> 00:18:27,270
+وفي بتتميز في إنها ال
+
+224
+00:18:29,630 --> 00:18:35,970
+الاطلاس it means انها ال spinal process فيها pivot
+
+225
+00:18:35,970 --> 00:18:41,690
+يعني زي شوكة عامل اللي هو فرعين وفي ان ال seven
+
+226
+00:18:41,690 --> 00:18:45,970
+cervical vertebra هي landmark تكون لو احنا اتحسسنا
+
+227
+00:18:45,970 --> 00:18:49,970
+في منطقة أسفل الرقبة بنلاقيها bears
+
+228
+00:18:52,260 --> 00:18:55,460
+ال science process تبعها هذه خواصة تقريبا ال
+
+229
+00:18:55,460 --> 00:19:02,400
+cervical أو مختصر لخواصة ال cervical vertebra
+
+230
+00:19:05,660 --> 00:19:09,820
+الـ thoracic vertebra فهي vertebra تقليدية لكن الـ
+
+231
+00:19:09,820 --> 00:19:14,280
+spinous process فيها أطول شوية وموجود فيها facets
+
+232
+00:19:14,280 --> 00:19:20,240
+للربب المعنى ان ال ribs هالقيتها او الرش بتيجي
+
+233
+00:19:20,240 --> 00:19:26,320
+تتسط فيها في منطقة في منطقة التهارب فهذه بس من
+
+234
+00:19:26,320 --> 00:19:29,660
+مميزاتها انها long spinous process وفيها rib
+
+235
+00:19:29,660 --> 00:19:33,420
+facets اما ال lumber فهي اكبر واحدة و اوسع واحدة
+
+236
+00:19:33,420 --> 00:19:40,630
+هي shortأول شي Large body thick تتحمل ضغط فيها
+
+237
+00:19:40,630 --> 00:19:44,750
+short spinous ال process موجود هي ليش أكبر واحدة
+
+238
+00:19:44,750 --> 00:19:50,050
+لأن هي اللي بتحمل الضغط كل ما فوقها من الجذع يعني
+
+239
+00:19:50,050 --> 00:19:54,950
+كل وزن ال trunk ال upper limbs هيكون موجود على هذه
+
+240
+00:19:54,950 --> 00:20:02,620
+المنطقة أما ال sacrum فهي عبارة عن effusionلأ خمسة
+
+241
+00:20:02,620 --> 00:20:08,340
+من ال vertebra فى عنا ميديا ال sacral الchrist
+
+242
+00:20:08,340 --> 00:20:12,460
+وعنا posterior sacral فرنن وال posterior wall of
+
+243
+00:20:12,460 --> 00:20:17,580
+the pelvic cavity هى بتكون مكوّنة من اللى هى ال
+
+244
+00:20:17,580 --> 00:20:22,480
+sacrum وفى ال sacral برمونتورى زى ما هو موضح عنا
+
+245
+00:20:22,480 --> 00:20:27,760
+بالشكل الموجودأما الكوكسيس فهي قلنا الـ tail bone
+
+246
+00:20:27,760 --> 00:20:33,260
+هي عبارة عن four fused vertebra هذه هي قلنا العضمة
+
+247
+00:20:33,260 --> 00:20:40,140
+اللي تبقى ويعاد بيها خلق الإنسان أو الحيوان مرة
+
+248
+00:20:42,370 --> 00:20:48,330
+طبعا الأكثر skeleton في through the life بيكون أول
+
+249
+00:20:48,330 --> 00:20:51,990
+ما بيبدأ ما بتبدأ ال curvature هذه بتبدأ في عينة
+
+250
+00:20:51,990 --> 00:20:57,510
+primary curvature بتبدأ في غوجنين شكله C شاب بشكل
+
+251
+00:20:57,510 --> 00:21:03,050
+حرف ال C بيبدأ يتشكل مع انمه فيبقى عينة ال sacral
+
+252
+00:21:03,050 --> 00:21:09,200
+وثوس ال curvature دولة primary بلواconvex
+
+253
+00:21:09,200 --> 00:21:12,160
+posteriorly أما ال secondary curvature زي ال
+
+254
+00:21:12,160 --> 00:21:16,980
+cervical و ال lumbar بيبدأ تشكيلهم كل ما تطورنا في
+
+255
+00:21:16,980 --> 00:21:20,580
+النمو طبعا ال cervical curvature بيبدأ من الهدراز
+
+256
+00:21:20,580 --> 00:21:24,960
+أول ما بيبدأ الطفل يرفع رأسه على هو في ال point
+
+257
+00:21:24,960 --> 00:21:28,800
+position فهو بيبدأ يشكل عنده هذا ال curve لما
+
+258
+00:21:28,800 --> 00:21:33,140
+بيمشي تبدأ تزيد ال curve لما تظهر بمظهرها اللي
+
+259
+00:21:33,140 --> 00:21:38,850
+احنا بنشوفه في ال adult moodطبعا هي كل وظيفتها
+
+260
+00:21:38,850 --> 00:21:45,690
+انها تعمل redistribution لل weight من ال upper
+
+261
+00:21:45,690 --> 00:21:51,310
+body ل ال lower limbs طبعا في انا three main curve
+
+262
+00:21:57,460 --> 00:22:01,680
+Kefosis هو إبارة عن exaggeration أو زيادة في
+
+263
+00:22:01,680 --> 00:22:07,140
+التراث الكيرفاتشار directly posteriorly بتسميها
+
+264
+00:22:07,140 --> 00:22:11,940
+humpbackback أو back lock أما ال lordosis فهي
+
+265
+00:22:11,940 --> 00:22:16,220
+مشهية ال lord بيسموها way back بيكون فيه زيادة في
+
+266
+00:22:16,220 --> 00:22:21,040
+ال number ال lordosis بيصير المظهر أنه في عندنا
+
+267
+00:22:21,040 --> 00:22:25,080
+big belly زي المرأة الحامل وفي عندنا big buttocks
+
+268
+00:22:25,080 --> 00:22:30,520
+في الخلف يعني من قدام في كرج وفي خلفيأما الـ
+
+269
+00:22:30,520 --> 00:22:33,240
+scoliosis فهي abnormal lateral curvature هذه
+
+270
+00:22:33,240 --> 00:22:37,780
+نشوفها في الـ posterior view بتطلع عندنا شكل ال
+
+271
+00:22:37,780 --> 00:22:43,660
+vertebral column مائل laterally فهذه بتكون عبارة
+
+272
+00:22:43,660 --> 00:22:47,950
+عن أحيانا بتكون structuralأو postural، الـ
+
+273
+00:22:47,950 --> 00:22:51,590
+postural بتكون ممكن تعديلها بال exercise، أما ال
+
+274
+00:22:51,590 --> 00:22:55,530
+structural فهذه بتحتاج بتاع تدخلات أخرى وهو ال
+
+275
+00:22:55,530 --> 00:22:58,510
+scoliosis the most common spinal curvature هي
+
+276
+00:22:58,510 --> 00:23:03,230
+بتنتج عن إيش؟ هي بتنتج عن مشكلة أثناء development
+
+277
+00:23:03,230 --> 00:23:08,370
+لل vertebral arch في حتى فترة ال interview أو بعد
+
+278
+00:23:10,790 --> 00:23:20,710
+هذه صورة توضحية لل .. ال .. ال handbag الثروس
+
+279
+00:23:20,710 --> 00:23:27,270
+الكاشف هو عبارة عن القفص الصدري، إيش وظيفة القفص
+
+280
+00:23:27,270 --> 00:23:33,410
+الصدري؟ إنه يحمي ال vital organs زي ال heart و ال
+
+281
+00:23:33,410 --> 00:23:38,520
+lungs، the trachea و ال oesophagusطبعا هدولة بدهم
+
+282
+00:23:38,520 --> 00:23:42,060
+بيحتاجوا protection طيب ال thoracic cage من إيش
+
+283
+00:23:42,060 --> 00:23:46,040
+بتكون؟ بتكون من ال rib، عن ال sternum و من الباك
+
+284
+00:23:46,040 --> 00:23:50,580
+ال thoracic vertebra طبعا في إن عضلات التنفس بتكون
+
+285
+00:23:50,580 --> 00:23:59,400
+كلها مثبتة في هذا ال .. في ال rib cageوكمان فى ان
+
+286
+00:23:59,400 --> 00:24:02,700
+عضلات اللى هى ال pectoral girdle و ال chest تكونك
+
+287
+00:24:02,700 --> 00:24:06,120
+و ال shoulder و ال back musculatures دايما بتكون
+
+288
+00:24:06,120 --> 00:24:10,300
+involved فى ال respiration طبعا هذا شكله فى هنا
+
+289
+00:24:10,300 --> 00:24:15,870
+عددمن واحد ما سبعة من ال ribs بنسميهم true ribs
+
+290
+00:24:15,870 --> 00:24:20,250
+وفي عندنا ال false ribs لإنها هي ليش true ribs
+
+291
+00:24:20,250 --> 00:24:24,410
+هلقيتها هنقول ليش لإن هدولة كل واحدة من ال ribs ع
+
+292
+00:24:24,410 --> 00:24:28,630
+طريق ال crustal cartilage بتكون إلها attachmentمع
+
+293
+00:24:28,630 --> 00:24:32,730
+الsterna اما ال first rib اللي هم من تمانية تقريبا
+
+294
+00:24:32,730 --> 00:24:37,030
+ال 12 في منهم ال 11 و 12 هدولة floating مالهونش اي
+
+295
+00:24:37,030 --> 00:24:40,770
+attachment مع اي اشي و هم مش coastal cartilage اما
+
+296
+00:24:40,770 --> 00:24:47,090
+من تمانية لعشرة فهم كلهم مع بعض attached في one
+
+297
+00:24:47,090 --> 00:24:51,510
+attachment او coastal cartilage واحد في الsterna
+
+298
+00:24:55,430 --> 00:24:59,490
+زي ما هنا شرحنا على الرسمة بنعيد الكلام أما ال
+
+299
+00:24:59,490 --> 00:25:04,170
+floating grip فهي مش ماعندهاش اي connection مع
+
+300
+00:25:04,170 --> 00:25:10,510
+السيرم هي floating عائمة وهذا
+
+301
+00:25:10,510 --> 00:25:20,880
+شكل ال rib كل rib بيكون فيهاتلتقي مع الـ sternum و
+
+302
+00:25:20,880 --> 00:25:25,800
+كمان من الناحية الأخرى تلتقي مع ال .. من الخلف مع
+
+303
+00:25:25,800 --> 00:25:32,400
+ال vertebra و بهيك احنا بنكون خلصنا و حديثنا عن ال
+
+304
+00:25:32,400 --> 00:25:35,880
+axial skeleton و المحاضرة القادمة تكون عن ال
+
+305
+00:25:35,880 --> 00:25:39,020
+perpendicular skeleton، يعطيكم العافية
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..c339cc7a0779c0b104267a8b42bb61ff0739b3f8
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 2174, "start": 4.98, "end": 21.74, "text": "بسم الله الرحمن الرحيم طلابنا الأعزاء اليوم استكمالة لمحادرات skeletal system الجزء التاني من المحادرة هنتكلم فيها عن ال axial skeleton اللي هو بيتمثل بال head، ال trunk", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 23032, 15040, 3555, 8315, 16247, 3615, 11622, 16606, 1975, 20292, 20498, 44713, 24793, 6027, 3660, 32767, 5016, 18513, 2288, 9307, 32321, 304, 1185, 25724, 11622, 38207, 16712, 7649, 1829, 9154, 9673, 5016, 18513, 25720, 8032, 29399, 4117, 19528, 8978, 11296, 18871, 2423, 46851, 25204, 13672, 1829, 31439, 4724, 36081, 2304, 12984, 1211, 20666, 1378, 12399, 2423, 19849], "avg_logprob": -0.1310634399527934, "compression_ratio": 1.5536723163841808, "no_speech_prob": 5.304813385009766e-06, "words": [{"start": 4.98, "end": 5.32, "word": "بسم", "probability": 0.905029296875}, {"start": 5.32, "end": 5.52, "word": " الله", "probability": 0.9638671875}, {"start": 5.52, "end": 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"probability": 0.84228515625}, {"start": 379.29, "end": 379.55, "word": " كلها", "probability": 0.979248046875}, {"start": 379.55, "end": 379.97, "word": " bone", "probability": 0.95556640625}, {"start": 379.97, "end": 381.21, "word": " فهذه", "probability": 0.9212239583333334}, {"start": 381.21, "end": 381.61, "word": " بتكون", "probability": 0.974853515625}, {"start": 381.61, "end": 382.11, "word": " تقيلة", "probability": 0.9493408203125}, {"start": 382.11, "end": 382.37, "word": " فهي", "probability": 0.9456380208333334}, {"start": 382.37, "end": 382.97, "word": " بتخفف", "probability": 0.9775390625}, {"start": 382.97, "end": 383.17, "word": " من", "probability": 0.98876953125}, {"start": 383.17, "end": 383.65, "word": " وزن", "probability": 0.9820963541666666}, {"start": 383.65, "end": 383.87, "word": " ال", "probability": 0.98095703125}, {"start": 383.87, "end": 384.31, "word": " skull", "probability": 0.69921875}, {"start": 384.31, "end": 385.03, "word": " و", "probability": 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{"start": 392.82, "end": 393.46, "word": " sinuses", "probability": 0.791259765625}, {"start": 393.46, "end": 394.08, "word": " موجودة", "probability": 0.9180908203125}, {"start": 394.08, "end": 394.42, "word": " بين", "probability": 0.97119140625}, {"start": 394.42, "end": 394.88, "word": " ال", "probability": 0.890625}, {"start": 394.88, "end": 395.14, "word": " two", "probability": 0.47900390625}, {"start": 395.14, "end": 396.24, "word": " pores", "probability": 0.72802734375}, {"start": 396.24, "end": 396.48, "word": " اللي", "probability": 0.790771484375}, {"start": 396.48, "end": 396.74, "word": " هو", "probability": 0.96923828125}, {"start": 396.74, "end": 397.6, "word": " الحواجب", "probability": 0.94970703125}, {"start": 397.6, "end": 398.1, "word": " ال", "probability": 0.7880859375}, {"start": 398.1, "end": 398.54, "word": " ethmoid", "probability": 0.7411295572916666}, {"start": 398.54, "end": 398.84, "word": " تحت", "probability": 0.982177734375}, {"start": 398.84, "end": 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على", "probability": 0.9296875}, {"start": 405.9, "end": 406.38, "word": " رؤوس", "probability": 0.47509765625}, {"start": 406.38, "end": 407.38, "word": " الخدود", "probability": 0.728515625}, {"start": 407.38, "end": 408.36, "word": " التانية", "probability": 0.54052734375}, {"start": 408.36, "end": 408.64, "word": " على", "probability": 0.7529296875}, {"start": 408.64, "end": 409.08, "word": " الناحية", "probability": 0.86590576171875}, {"start": 409.08, "end": 409.32, "word": " التانية", "probability": 0.9552408854166666}], "temperature": 1.0}, {"id": 19, "seek": 43488, "start": 411.56, "end": 434.88, "text": "في عندنا الـ Hyaluron وفي عندنا الـ Fontanels الـ Fontanels هي عبارة عن Vibrous Membrane بيعمل زي فتحات موجودة في الـ skull بتسميها اليفوخ أو النفوخ على زي ما بيوصفوه أمهاتنا وجداتنا لما بيولد الطفل عادة بنولد بقوله نفوخ و مفتوح", "tokens": [41185, 43242, 8315, 2423, 39184, 5701, 304, 374, 266, 4032, 41185, 43242, 8315, 2423, 39184, 43901, 282, 1625, 2423, 39184, 43901, 282, 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0.95947265625}, {"start": 1487.09, "end": 1488.01, "word": " attachment", "probability": 0.8359375}, {"start": 1488.01, "end": 1488.51, "word": " او", "probability": 0.8486328125}, {"start": 1488.51, "end": 1488.93, "word": " coastal", "probability": 0.88232421875}, {"start": 1488.93, "end": 1489.77, "word": " cartilage", "probability": 0.979248046875}, {"start": 1489.77, "end": 1490.63, "word": " واحد", "probability": 0.958984375}, {"start": 1490.63, "end": 1490.83, "word": " في", "probability": 0.8916015625}, {"start": 1490.83, "end": 1491.51, "word": " الsterna", "probability": 0.8955078125}], "temperature": 1.0}, {"id": 66, "seek": 151615, "start": 1495.43, "end": 1516.15, "text": "زي ما هنا شرحنا على الرسمة بنعيد الكلام أما ال floating grip فهي مش ماعندهاش اي connection مع السيرم هي floating عائمة وهذا شكل ال rib كل rib بيكون فيها", "tokens": [11622, 1829, 19446, 34105, 13412, 2288, 5016, 8315, 15844, 34892, 38251, 3660, 44945, 3615, 25708, 2423, 28820, 10943, 5551, 15042, 2423, 12607, 12007, 6156, 3224, 1829, 37893, 19446, 3615, 41260, 3224, 33599, 1975, 1829, 4984, 20449, 21136, 13546, 2304, 39896, 12607, 6225, 16373, 46007, 37037, 15730, 13412, 28820, 2423, 9162, 28242, 9162, 4724, 1829, 30544, 8978, 11296], "avg_logprob": -0.2710129222993193, "compression_ratio": 1.484472049689441, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 1495.43, "end": 1495.73, "word": "زي", "probability": 0.4608154296875}, {"start": 1495.73, "end": 1495.83, "word": " ما", "probability": 0.8017578125}, {"start": 1495.83, "end": 1496.09, "word": " هنا", "probability": 0.326416015625}, {"start": 1496.09, "end": 1496.95, "word": " شرحنا", "probability": 0.9683837890625}, {"start": 1496.95, "end": 1497.15, "word": " على", "probability": 0.7626953125}, {"start": 1497.15, "end": 1497.77, "word": " الرسمة", "probability": 0.9114583333333334}, {"start": 1497.77, "end": 1498.57, "word": " بنعيد", "probability": 0.7840169270833334}, {"start": 1498.57, "end": 1499.13, "word": " الكلام", "probability": 0.9137369791666666}, {"start": 1499.13, "end": 1499.37, "word": " أما", "probability": 0.755615234375}, {"start": 1499.37, "end": 1499.49, "word": " ال", "probability": 0.55517578125}, {"start": 1499.49, "end": 1499.75, "word": " floating", "probability": 0.88330078125}, {"start": 1499.75, "end": 1500.09, "word": " grip", "probability": 0.41455078125}, {"start": 1500.09, "end": 1500.65, "word": " فهي", "probability": 0.9415690104166666}, {"start": 1500.65, "end": 1501.01, "word": " مش", "probability": 0.38134765625}, {"start": 1501.01, "end": 1501.59, "word": " ماعندهاش", "probability": 0.831640625}, {"start": 1501.59, "end": 1501.83, "word": " اي", "probability": 0.779052734375}, {"start": 1501.83, "end": 1502.37, "word": " connection", "probability": 0.73095703125}, {"start": 1502.37, "end": 1504.17, "word": " مع", "probability": 0.8486328125}, {"start": 1504.17, "end": 1504.71, "word": " السيرم", "probability": 0.4270426432291667}, {"start": 1504.71, "end": 1504.95, "word": " هي", "probability": 0.8330078125}, {"start": 1504.95, "end": 1505.63, "word": " floating", "probability": 0.98095703125}, {"start": 1505.63, "end": 1506.29, "word": " عائمة", "probability": 0.93359375}, {"start": 1506.29, "end": 1510.51, "word": " وهذا", "probability": 0.91015625}, {"start": 1510.51, "end": 1511.47, "word": " شكل", "probability": 0.98876953125}, {"start": 1511.47, "end": 1512.23, "word": " ال", "probability": 0.919921875}, {"start": 1512.23, "end": 1513.53, "word": " rib", "probability": 0.8154296875}, {"start": 1513.53, "end": 1514.77, "word": " كل", "probability": 0.81298828125}, {"start": 1514.77, "end": 1515.23, "word": " rib", "probability": 0.931640625}, {"start": 1515.23, "end": 1515.61, "word": " بيكون", "probability": 0.8414713541666666}, {"start": 1515.61, "end": 1516.15, "word": " فيها", "probability": 0.984619140625}], "temperature": 1.0}, {"id": 67, "seek": 153902, "start": 1517.48, "end": 1539.02, "text": "تلتقي مع الـ sternum و كمان من الناحية الأخرى تلتقي مع ال .. من الخلف مع ال vertebra و بهيك احنا بنكون خلصنا و حديثنا عن ال axial skeleton و المحاضرة القادمة تكون عن ال perpendicular skeleton، يعطيكم العافية", "tokens": [2655, 1211, 2655, 38436, 20449, 2423, 39184, 38312, 449, 4032, 9122, 2304, 7649, 9154, 2423, 8315, 5016, 10632, 16247, 34740, 7578, 6055, 1211, 2655, 38436, 20449, 2423, 4386, 9154, 33962, 46538, 20449, 2423, 16167, 6198, 4032, 39627, 1829, 4117, 1975, 5016, 8315, 44945, 30544, 16490, 1211, 9381, 8315, 4032, 11331, 16254, 12984, 8315, 18871, 2423, 46851, 25204, 4032, 9673, 5016, 46958, 25720, 25062, 18513, 46007, 6055, 30544, 18871, 2423, 26734, 25204, 12399, 37495, 9566, 1829, 24793, 18863, 31845, 10632], "avg_logprob": -0.2191406276077032, "compression_ratio": 1.625, "no_speech_prob": 9.423494338989258e-05, "words": [{"start": 1517.48, "end": 1518.14, "word": "تلتقي", "probability": 0.84130859375}, {"start": 1518.14, "end": 1518.46, "word": " مع", "probability": 0.9677734375}, {"start": 1518.46, "end": 1518.78, "word": " الـ", "probability": 0.566650390625}, {"start": 1518.78, "end": 1519.96, "word": " sternum", "probability": 0.708984375}, {"start": 1519.96, "end": 1520.88, "word": " و", "probability": 0.88623046875}, {"start": 1520.88, "end": 1521.36, "word": " كمان", "probability": 0.7880045572916666}, {"start": 1521.36, "end": 1522.28, "word": " من", "probability": 0.9775390625}, {"start": 1522.28, "end": 1522.7, "word": " الناحية", "probability": 0.8316650390625}, {"start": 1522.7, "end": 1523.06, "word": " الأخرى", "probability": 0.9630533854166666}, {"start": 1523.06, "end": 1523.62, "word": " تلتقي", "probability": 0.915771484375}, {"start": 1523.62, "end": 1523.94, "word": " مع", "probability": 0.55419921875}, {"start": 1523.94, "end": 1524.52, "word": " ال", "probability": 0.93408203125}, {"start": 1524.52, "end": 1524.76, "word": " ..", "probability": 0.8564453125}, {"start": 1524.76, "end": 1524.96, "word": " من", "probability": 0.9765625}, {"start": 1524.96, "end": 1525.48, "word": " الخلف", "probability": 0.969482421875}, {"start": 1525.48, "end": 1525.8, "word": " مع", "probability": 0.98193359375}, {"start": 1525.8, "end": 1526.26, "word": " ال", "probability": 0.994140625}, {"start": 1526.26, "end": 1526.9, "word": " vertebra", "probability": 0.911865234375}, {"start": 1526.9, "end": 1528.24, "word": " و", "probability": 0.79736328125}, {"start": 1528.24, "end": 1528.9, "word": " بهيك", "probability": 0.7000325520833334}, {"start": 1528.9, "end": 1529.04, "word": " احنا", "probability": 0.9103190104166666}, {"start": 1529.04, "end": 1529.62, "word": " بنكون", "probability": 0.940185546875}, {"start": 1529.62, "end": 1530.68, "word": " خلصنا", "probability": 0.9571533203125}, {"start": 1530.68, "end": 1530.78, "word": " و", "probability": 0.9541015625}, {"start": 1530.78, "end": 1531.26, "word": " حديثنا", "probability": 0.912109375}, {"start": 1531.26, "end": 1531.64, "word": " عن", "probability": 0.99609375}, {"start": 1531.64, "end": 1532.4, "word": " ال", "probability": 0.95263671875}, {"start": 1532.4, "end": 1533.22, "word": " axial", "probability": 0.53857421875}, {"start": 1533.22, "end": 1533.82, "word": " skeleton", "probability": 0.7939453125}, {"start": 1533.82, "end": 1534.3, "word": " و", "probability": 0.66796875}, {"start": 1534.3, "end": 1534.7, "word": " المحاضرة", "probability": 0.9700927734375}, {"start": 1534.7, "end": 1535.14, "word": " القادمة", "probability": 0.98486328125}, {"start": 1535.14, "end": 1535.44, "word": " تكون", "probability": 0.615478515625}, {"start": 1535.44, "end": 1535.7, "word": " عن", "probability": 0.98388671875}, {"start": 1535.7, "end": 1535.88, "word": " ال", "probability": 0.95751953125}, {"start": 1535.88, "end": 1536.68, "word": " perpendicular", "probability": 0.326416015625}, {"start": 1536.68, "end": 1538.2, "word": " skeleton،", "probability": 0.6085205078125}, {"start": 1538.2, "end": 1538.58, "word": " يعطيكم", "probability": 0.78875732421875}, {"start": 1538.58, "end": 1539.02, "word": " العافية", "probability": 0.670654296875}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1539.274, "duration_after_vad": 1497.245624999998}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..559b0e386bde81677ea5fc715f1891692b3365a8
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/6jK_H6JGrYs_raw.srt
@@ -0,0 +1,1220 @@
+1
+00:00:04,980 --> 00:00:09,940
+بسم الله الرحمن الرحيم طلابنا الأعزاء اليوم
+
+2
+00:00:09,940 --> 00:00:14,260
+استكمالة لمحادرات skeletal system الجزء التاني من
+
+3
+00:00:14,260 --> 00:00:17,680
+المحادرة هنتكلم فيها عن ال axial skeleton اللي هو
+
+4
+00:00:17,680 --> 00:00:25,390
+بيتمثل بال head، ال trunkand the vertebral column
+
+5
+00:00:25,390 --> 00:00:29,790
+ان شاء الله تكون الصور التوضيحية اللى موجودة معنا
+
+6
+00:00:29,790 --> 00:00:33,690
+فى ال presentation بتساعد فى الشرح هي اضطرد انه
+
+7
+00:00:33,690 --> 00:00:36,770
+كان يكون معانا ال skeleton اليوم بس مع صعوبة
+
+8
+00:00:36,770 --> 00:00:39,450
+التنقل انا قولت الصور ان شاء الله تكون التوضيحية
+
+9
+00:00:39,450 --> 00:00:44,980
+بتعطينا فكرة عن ال skeletonال Axial skeleton طبيعي
+
+10
+00:00:44,980 --> 00:00:48,320
+بتكون من ال head, the neck and the trunk، ال trunk
+
+11
+00:00:48,320 --> 00:00:54,860
+طبعا اللي هو بيشمل الجدع، ما بنسمي احنا الجزاء،
+
+12
+00:00:54,860 --> 00:00:59,520
+اما ال perpendicular system او skeleton فهو عبارة
+
+13
+00:00:59,520 --> 00:01:03,250
+عن ال upper limbs، ال lower limbsالـ pictorial
+
+14
+00:01:03,250 --> 00:01:08,170
+girdle and pelvic girdle طبعا المحاضرة اللي جاي ان
+
+15
+00:01:08,170 --> 00:01:10,910
+شاء الله هتكون على pedicular system اليوم هنتكلم
+
+16
+00:01:10,910 --> 00:01:16,070
+عن ال axial skeleton ال axial skeleton حسب ما هو
+
+17
+00:01:16,070 --> 00:01:22,950
+موضح بالرسم في ان ال headبكل العظام المكوّنة
+
+18
+00:01:22,950 --> 00:01:28,670
+لـSkull في عندنا الـNeck وفي عندنا thoracic cage
+
+19
+00:01:28,670 --> 00:01:33,910
+زي ما هو مضحن بالرسم و ال vertebral column as well
+
+20
+00:01:33,910 --> 00:01:38,850
+هنتكلم عنهم بالتفصيل ان شاء الله طبعا ال skull هي
+
+21
+00:01:38,850 --> 00:01:43,390
+عبارة عن الجمجمة اللي وظفتها اللي بتحتوي عن تمان
+
+22
+00:01:43,390 --> 00:01:49,650
+عظام تمان عظام هذه وظفتها انها تحيط و تغلق على ال
+
+23
+00:01:49,650 --> 00:01:54,290
+brainطبعا في ان ال face bone ال face bone هي دي
+
+24
+00:01:54,290 --> 00:02:00,350
+اتناشر عضمة وزفتها انها بتعمل passengers ل
+
+25
+00:02:00,350 --> 00:02:04,650
+digestive و respiratory system بتعملنا entrance
+
+26
+00:02:04,650 --> 00:02:09,990
+وكمان بتعطيني مكان حتى ال facial muscle اللي هي
+
+27
+00:02:09,990 --> 00:02:15,630
+بتأثر على ال facial expressions بتكون attached في
+
+28
+00:02:15,630 --> 00:02:22,210
+هذه ال .. ال boneطبعا بالنسبة لـ cranium احنا كلنا
+
+29
+00:02:22,210 --> 00:02:26,410
+حافظين ان في عندنا عضمات رئيسية و كبيرة زي ال
+
+30
+00:02:26,410 --> 00:02:32,230
+frontal bone زي ما هم وضحها بهذا الشكل هي عضمة
+
+31
+00:02:32,230 --> 00:02:38,030
+كبيرة اللي هي عضمة الجبهةو في عندنا ال parietal في
+
+32
+00:02:38,030 --> 00:02:41,230
+عندنا عضمتين هي ال frontal عضمة واحدة لكن في عندنا
+
+33
+00:02:41,230 --> 00:02:47,490
+عضمتين موجودين في جناب الجنجمة هي ال parietal و
+
+34
+00:02:47,490 --> 00:02:53,070
+تحتهم على طول بيكون في عندنا ال occipital في خلفية
+
+35
+00:02:53,070 --> 00:02:58,930
+الرأس عضمة واحدةوكمان هنا ال temporal اللي هي فوق
+
+36
+00:02:58,930 --> 00:03:03,850
+الأذن ومحيط الأذن في عنا عضلتين على الناحية تانية
+
+37
+00:03:03,850 --> 00:03:07,290
+طبعا احنا من ال 80 cranial bones احنا بتكلم عن
+
+38
+00:03:07,290 --> 00:03:12,910
+الرأسيات ان في انا اكتر من هم عددهم تمانية لأنه في
+
+39
+00:03:12,910 --> 00:03:19,310
+pairs وفي only one boneفالشكل هنا واضح بالعضمات
+
+40
+00:03:19,310 --> 00:03:25,850
+اللي موجودة وأماكن تواجدها تماما ال skull بقل نقول
+
+41
+00:03:25,850 --> 00:03:31,190
+هي بتشكل الحماية ل ال brain وبنفس الوقت فيها
+
+42
+00:03:31,190 --> 00:03:34,790
+cavities ال cavities هذه إيش وظفتها؟
+
+43
+00:03:37,430 --> 00:03:40,570
+لو ال brain أو ال cranial cavity هي أكبر cavity
+
+44
+00:03:40,570 --> 00:03:44,830
+تقريبا موجودة في هذه المنطقة بتسكر و بتعمل
+
+45
+00:03:44,830 --> 00:03:48,870
+cushions لل brain بتحمي ال brain و بقى كمان من
+
+46
+00:03:48,870 --> 00:03:52,590
+خلال ال meninges اللي موجودة بتشكل حماية أكبر و
+
+47
+00:03:52,590 --> 00:03:56,550
+بتعمل shock absorption كمان لأي صدمة لإن احنا برا
+
+48
+00:03:56,550 --> 00:04:01,290
+في ال brain جزء حساس من جسم الإنسان و هو عبارة عن
+
+49
+00:04:01,290 --> 00:04:04,950
+ال control تبع الجسم كله فبالتالي بحتاج لحمية كتير
+
+50
+00:04:04,950 --> 00:04:09,050
+كبيرةلكن مش مكوّن من عدة إضام مش عضمة واحدة لإنه
+
+51
+00:04:09,050 --> 00:04:12,390
+هذه الإضام، مجموعة الإضام هذه مع الفتحات اللي
+
+52
+00:04:12,390 --> 00:04:17,690
+بينها بتسمح لانمو، ايضا في انفتاحات تانية لإن
+
+53
+00:04:17,690 --> 00:04:22,770
+العين، لإن العيون موجودة برضه في فتحات نسميها ال
+
+54
+00:04:22,770 --> 00:04:27,010
+orbits، فينا ال oral cavity عشان اللي هي بتمثل ال
+
+55
+00:04:27,010 --> 00:04:30,150
+mouth عشان نقدر ناكل، فينا ال nasal cavity و ال
+
+56
+00:04:30,150 --> 00:04:34,090
+paranasal sinuses عشان ال
+
+57
+00:04:35,890 --> 00:04:42,270
+تساعد على عملية التنفس والـ Paranasal Sinuses هذه
+
+58
+00:04:42,270 --> 00:04:50,210
+عشان تساعد هتزات الصوت لما احنا مصدر الأصل طبعا
+
+59
+00:04:50,210 --> 00:04:53,510
+هنا العضمات الصغيرة هذه موضحة بالرسم زي
+
+60
+00:04:53,510 --> 00:04:57,870
+الـSphenoid و
+
+61
+00:04:57,870 --> 00:05:03,430
+الـ Ethmoidوالـ maxillary هنا عظمة الوجه الان فانا
+
+62
+00:05:03,430 --> 00:05:06,230
+قاعدة بتكلم عن ال facial skeleton ال maxillary
+
+63
+00:05:06,230 --> 00:05:12,910
+اللي هي عظمة الفك العلوية ال ال palatine فما هي
+
+64
+00:05:12,910 --> 00:05:19,470
+موضحة بالرسم فوق الفك تحت ال الان is a genetics
+
+65
+00:05:19,470 --> 00:05:26,730
+اللي هي عبارة عن عظام الخد بخدودو اللى كرمل تحت
+
+66
+00:05:26,730 --> 00:05:35,550
+العين و نزل حوالين الناض و الفومر طبعا
+
+67
+00:05:35,550 --> 00:05:44,170
+فى كتراجه على حسب الرسم العظام كلها عظام الوجه ال
+
+68
+00:05:44,170 --> 00:05:46,210
+mandible الفك
+
+69
+00:05:49,430 --> 00:05:53,890
+نتروح للـ sinuses إيش هي ال sinuses؟ هي عبارة عن
+
+70
+00:05:53,890 --> 00:05:59,670
+فتحات تهوية موجودة في ال skull lining with mucous
+
+71
+00:05:59,670 --> 00:06:03,530
+membrane على أساس أنه لما يدخل الهواء أو ال air
+
+72
+00:06:03,530 --> 00:06:08,450
+إلى ال lungs يبقى humidified and warm بتدفي و
+
+73
+00:06:08,450 --> 00:06:15,550
+بترتبه عشان يدخل الجاف إلى الرئتينطبعا بتخلي ال
+
+74
+00:06:15,550 --> 00:06:18,950
+skull خفيفة لأنها لو كانت كلها compact bone او
+
+75
+00:06:18,950 --> 00:06:23,650
+كانت كلها bone فهذه بتكون تقيلة فهي بتخفف من وزن
+
+76
+00:06:23,650 --> 00:06:28,750
+ال skull و بتعطيني الصوت او الاهتزازات الخاصة
+
+77
+00:06:28,750 --> 00:06:33,460
+بالصوتفينا أربع من الـ sinuses ال frontal sinuses
+
+78
+00:06:33,460 --> 00:06:38,540
+موجودة بين ال two pores اللي هو الحواجب ال ethmoid
+
+79
+00:06:38,540 --> 00:06:44,160
+تحت منها شوية و ال sphenoid أقرب إلى الانف و ال
+
+80
+00:06:44,160 --> 00:06:48,640
+auxiliary موجودة على رؤوس الخدود التانية على
+
+81
+00:06:48,640 --> 00:06:55,720
+الناحية التانيةفي عندنا الـ Hyaluron وفي عندنا الـ
+
+82
+00:06:55,720 --> 00:06:59,380
+Fontanels الـ Fontanels هي عبارة عن Vibrous
+
+83
+00:06:59,380 --> 00:07:04,200
+Membrane بيعمل زي فتحات موجودة في الـ skull
+
+84
+00:07:04,200 --> 00:07:09,840
+بتسميها اليفوخ أو النفوخ على زي ما بيوصفوه أمهاتنا
+
+85
+00:07:09,840 --> 00:07:14,400
+وجداتنا لما بيولد الطفل عادة بنولد بقوله نفوخ و
+
+86
+00:07:14,400 --> 00:07:18,940
+مفتوحليش يعني نفوخ و مفتوح؟ يعني في فتحة ما بين
+
+87
+00:07:18,940 --> 00:07:26,460
+الـ skull bones تسمح لمرونة، نوع من المرونة في الـ
+
+88
+00:07:26,460 --> 00:07:29,480
+skull ليش؟ لأن هو هذا الطفل اللي ما بده يخرج من ..
+
+89
+00:07:29,480 --> 00:07:34,280
+من .. من بطن الأم بيكون بده يخرج من بين عظام الحُر
+
+90
+00:07:34,510 --> 00:07:38,790
+طبعا بيصير أنه فيه إمكانية خروج و بتنضغط هذه
+
+91
+00:07:38,790 --> 00:07:42,930
+العضام على بعضها بيصيرلها كلها عشان تسمح بالبسج ل
+
+92
+00:07:42,930 --> 00:07:48,170
+ال head of the baby طبعا هذا بتسكر بعد سن خمس عشر
+
+93
+00:07:48,170 --> 00:07:52,770
+سنة كمان عشان يسمح لعملية نمو ل brain و نمو لل
+
+94
+00:07:52,770 --> 00:07:58,690
+skull طبعا هو عبارة عن thickened fibrous membraneو
+
+95
+00:07:58,690 --> 00:08:02,810
+it is not ossified بيبقى له soft spots لو حطينا
+
+96
+00:08:02,810 --> 00:08:07,130
+ايدنا على نفوخ ال baby بنلاقي انه في فتحة هذه فتحة
+
+97
+00:08:07,130 --> 00:08:12,110
+الي فوق وهذه الفتحة خطيرة جدا لأنه اي قلق هدا هدا
+
+98
+00:08:12,110 --> 00:08:17,190
+حد ممكن توصل لهذا المكان ممكن تشكل خطورة على ال
+
+99
+00:08:17,190 --> 00:08:23,930
+brain تبع هذا الطفلطبعا الـ newborn عادة بيولد
+
+100
+00:08:23,930 --> 00:08:28,610
+بشكل ال .. ال .. ال head عنده زي المخروط كده ليش؟
+
+101
+00:08:28,610 --> 00:08:34,450
+لأنه ال head ساعت ال .. خروجه من ال .. فتحة ال ..
+
+102
+00:08:34,450 --> 00:08:37,770
+او من عظمات الحواب تبين ضغط تبصير overlapping أو
+
+103
+00:08:37,770 --> 00:08:41,710
+collapse لهذه الأنظام عسى انه تسمح في البسش فبطلع
+
+104
+00:08:41,710 --> 00:08:46,910
+الرأس عامل زي ال .. المخروط كون شانوالصورة هنا
+
+105
+00:08:46,910 --> 00:08:51,330
+بتوضح هي بتودينا .. بتودينا وين هذه ال .. ال
+
+106
+00:08:51,330 --> 00:08:55,170
+fontanelles اللي خلالها بيصير عملية نمول ال skull
+
+107
+00:08:55,170 --> 00:08:58,910
+و بنفس الوقت بيصير enclose و sutures بعد ال
+
+108
+00:08:58,910 --> 00:09:06,590
+maturation ل ال bones of the skull ال sutures are
+
+109
+00:09:06,590 --> 00:09:12,850
+immovable fibrous zonesلما نجي ندرس عن ال joints
+
+110
+00:09:12,850 --> 00:09:16,370
+أنه في نوع من أنواع ال joints it's immovable و the
+
+111
+00:09:16,370 --> 00:09:21,150
+fibrous joints هي موجودة في موجود فرغات كانت
+
+112
+00:09:21,150 --> 00:09:24,270
+موجودة بين العضام لإن هي مجموعة من العضام ملتحمة
+
+113
+00:09:24,270 --> 00:09:29,070
+بتلتحم بعد سن بتصير dense regular connective
+
+114
+00:09:29,070 --> 00:09:35,270
+tissue عاملة زي ال suture شكلها و بتمسك ال bones
+
+115
+00:09:35,270 --> 00:09:41,230
+firmly together في منطقة ال sutureall the cranium
+
+116
+00:09:41,230 --> 00:09:45,170
+allow the cranium to grow and expand during
+
+117
+00:09:45,170 --> 00:09:48,550
+childhood عشان الراس تكبر بالعربي يعني بالأخر لو
+
+118
+00:09:48,550 --> 00:09:51,430
+انولد الراس لو انخلق الراس بنفس الحجم اللي هو
+
+119
+00:09:51,430 --> 00:09:56,050
+موجود عليه لما بنصير فيه adult دي بتكون مشكلة كتير
+
+120
+00:09:56,050 --> 00:09:59,710
+كبيرة في عملية ال delivery لل baby فأكيد أنه لازم
+
+121
+00:09:59,710 --> 00:10:04,930
+يسمح لعملية البناء للعظيم وكبر حجم الراس حتى
+
+122
+00:10:04,930 --> 00:10:08,430
+يتناسب مع كبر حجم ال brain لأن ال brain برضه ابيان
+
+123
+00:10:08,730 --> 00:10:12,470
+in other words when cranial growth has stopped the
+
+124
+00:10:12,470 --> 00:10:16,810
+suture refused and obliterated خلاص بتصير زي ما
+
+125
+00:10:16,810 --> 00:10:24,410
+احنا شايفينها بالشكل عبارة عن ستر طبيعية
+
+126
+00:10:24,410 --> 00:10:30,310
+بتلتحن فيها العضام زي ما احنا شايفينها بهذا الشكل
+
+127
+00:10:33,870 --> 00:10:37,050
+طيب إيش ال function of the vertebral column؟ احنا
+
+128
+00:10:37,050 --> 00:10:42,010
+لقيت خلصنا جزء ال skull، بنروح لل vertebral column
+
+129
+00:10:42,010 --> 00:10:46,610
+طيب إيش وظيفته؟ أول حاجة في عندنا الواد بيصير في
+
+130
+00:10:46,610 --> 00:10:51,070
+support، مانقاش، بدنا نصير .. بدنا نوقف احنا مثلا
+
+131
+00:10:51,070 --> 00:10:57,040
+زي ما أنا واقفة هناأنا وقفة على إش ووقفة على رجليا
+
+132
+00:10:57,040 --> 00:11:01,320
+لكن هال weight هذا اللي بيجي من ال head إلى القدم
+
+133
+00:11:01,320 --> 00:11:05,280
+بنتقل عن طريق إش عن طريق ال skull بيجي ال skull
+
+134
+00:11:05,280 --> 00:11:11,470
+وزنها بينزل على ال neck من ال neck بيروح علىبتوزع
+
+135
+00:11:11,470 --> 00:11:14,830
+على ال shoulder وبنزل back على ال vertebral column
+
+136
+00:11:14,830 --> 00:11:19,090
+بتوزع عن طريق أظام الحاض وبنزل عن طريق ال two hips
+
+137
+00:11:19,090 --> 00:11:23,790
+لحد يوصل للأرض عن طريق الفوتي فانا لما بدي أوقف
+
+138
+00:11:23,790 --> 00:11:29,070
+بوقف على اش بوقف على العدم عدم اش انا عمليا بوقف
+
+139
+00:11:29,070 --> 00:11:33,270
+على عدم اللي هو lower limbs لكن ال weight هذا
+
+140
+00:11:33,270 --> 00:11:37,890
+بيتوزع عن طريق الحاض من فوق لتحتطبعا الـ
+
+141
+00:11:37,890 --> 00:11:40,530
+protection للـ spinal cord هذا الـ protection زي
+
+142
+00:11:40,530 --> 00:11:43,790
+ما الـ skull بتعمل الـ protection للبرن ال spinal
+
+143
+00:11:43,790 --> 00:11:48,750
+cord كمان اللي موجود في الدهر بده ال protection من
+
+144
+00:11:48,750 --> 00:11:52,590
+أيش؟ من الأضام اللي موجودة لأنه في عندنا مجموعة من
+
+145
+00:11:52,590 --> 00:11:56,770
+ال .. في عندنا أول أشيه النخاع وفي عندنا ال spinal
+
+146
+00:11:56,770 --> 00:12:02,750
+nerves اللي بتطلع عشان تغدي العضلات و تساعد على
+
+147
+00:12:02,750 --> 00:12:08,250
+الحركة اللي بتاعة تتقدر للحركة كمانلما يكون في عنا
+
+148
+00:12:08,250 --> 00:12:12,950
+ال vertebral column fused فالحركة بتكون صعبة فهي
+
+149
+00:12:12,950 --> 00:12:18,250
+وجود spinal cord على شكل حلقة ال spinal vertebra
+
+150
+00:12:18,250 --> 00:12:22,670
+على شكل حلقات او vertebral column على شكل حلقاته
+
+151
+00:12:22,670 --> 00:12:27,130
+between in between each two في عنا disc هذا بيسمحي
+
+152
+00:12:27,130 --> 00:12:30,690
+الحركة فانا بقدر اوطي بقدر ارفع رأسي بقدر امايل
+
+153
+00:12:30,690 --> 00:12:34,590
+على اليمين امايل على الشمال ارفع رأسي فوق تحت وكده
+
+154
+00:12:34,590 --> 00:12:40,100
+للاتنين الحاضر او اتنينالجدع و ارفعه كمان احنا في
+
+155
+00:12:40,100 --> 00:12:44,240
+عندنا عضلات هذه العضلات هي اللي بدها تشكل ال
+
+156
+00:12:44,240 --> 00:12:47,640
+movement العظام هي عبارة عن ال liver الراوافع
+
+157
+00:12:47,640 --> 00:12:52,580
+بيكون في عندي مجال ان انا يكون في عندي attachments
+
+158
+00:12:52,580 --> 00:12:56,560
+على ال muscle في عندنا muscle attached to the head
+
+159
+00:12:56,560 --> 00:12:59,660
+to the neck ال upper extremity و ال thorax كلها
+
+160
+00:12:59,660 --> 00:13:04,360
+بتكون موجودة على او معظمها اللي هي attachments على
+
+161
+00:13:04,360 --> 00:13:10,230
+ال vertebral columnطبعا بالنسبة لأعداد ال bone
+
+162
+00:13:10,230 --> 00:13:16,990
+يعني 33 bone في ال adult مقسمة لخمسة categories
+
+163
+00:13:16,990 --> 00:13:20,810
+الخمسة categories هذه هي عبارة عن cervical
+
+164
+00:13:20,810 --> 00:13:27,170
+vertebra سبعة في ال neck region twelve في ال
+
+165
+00:13:27,170 --> 00:13:33,650
+vertebralفي الـthoracic region خمسة في الـlower
+
+166
+00:13:33,650 --> 00:13:37,570
+back اللي مسموها الخمسة القطنية وفيه هنا خمسة
+
+167
+00:13:37,570 --> 00:13:41,450
+fused في الـsacrum اللي احنا شايفينهم بالرسم هنا
+
+168
+00:13:41,450 --> 00:13:48,460
+الـsacral vertebra هي خمسة لكن fused togetherمش
+
+169
+00:13:48,460 --> 00:13:52,380
+mobile inferior to the lumbar vertebra وarticulate
+
+170
+00:13:52,380 --> 00:13:57,640
+with the coccygeal أو الـcoccyx هي عبارة عن عضمة
+
+171
+00:13:57,640 --> 00:14:05,380
+الديل عضمة الديل هذه هي اللي بتبقى بعد ما نقول إلى
+
+172
+00:14:05,380 --> 00:14:10,620
+التراب فهي اللي بيقود منها خلق أو إعادة الخلق
+
+173
+00:14:10,620 --> 00:14:13,940
+للأشخاص فهي العضمة الوحيدة اللي بتبقى من جسم
+
+174
+00:14:13,940 --> 00:14:21,110
+الإنسان لتبلغطبعا فيه ان في
+
+175
+00:14:21,110 --> 00:14:26,710
+ال lumber و ال cervical و ال thoracic هو العمول
+
+176
+00:14:26,710 --> 00:14:32,750
+الفقاري احنا بنسميه مش straight lineفيه curves ال
+
+177
+00:14:32,750 --> 00:14:37,750
+curves هذه بتبدأ نمو و تطور فيها من و احنا أجلنا و
+
+178
+00:14:37,750 --> 00:14:43,330
+بعدها في فترة الطفولة بتبدأ تتشكل فعينا في
+
+179
+00:14:43,330 --> 00:14:48,770
+cervical and lumbar curvature concave posteriorly
+
+180
+00:14:48,770 --> 00:14:53,050
+ال concavity او التقاعر تبعهم الى الخلف وفيه ال
+
+181
+00:14:53,050 --> 00:15:02,310
+thoracic والsacral الالتقاعر فيهم إلى الأمام فهي
+
+182
+00:15:02,310 --> 00:15:05,730
+الـ cervical and lumbar concave posteriorly أما
+
+183
+00:15:05,730 --> 00:15:10,690
+الـ thoracic and sacral convex posteriorly في
+
+184
+00:15:10,690 --> 00:15:16,550
+محددة من الخلط طبعا هذه الـcervitures إيش وظيفتها؟
+
+185
+00:15:16,550 --> 00:15:20,730
+بتعمل ك shock absorption بتزود ال mobility تبع
+
+186
+00:15:20,730 --> 00:15:27,930
+الجسم وبتحافظ على الدونةبتعطي المرونة أما تركيبة
+
+187
+00:15:27,930 --> 00:15:32,390
+ال vertebra نفسها فهي عبارة عن body اللي احنا
+
+188
+00:15:32,390 --> 00:15:40,720
+شايفينها فيه بديكلس بتوصل ل transversal processمع
+
+189
+00:15:40,720 --> 00:15:45,280
+ال body وفيه إنه حاجة اسمها Lamina وفيه إنه بستيرو
+
+190
+00:15:45,280 --> 00:15:49,180
+ال spine زي إحنا شايفينه وفيه إن الفرامين هذا اللي
+
+191
+00:15:49,180 --> 00:15:54,180
+بيفوت منه أو بيحتوي على النخاع الشوكي أو ال spinal
+
+192
+00:15:54,180 --> 00:15:57,840
+cord طبعا لما بيصير ضغط أو بيصير فيه إنه disk
+
+193
+00:15:57,840 --> 00:16:01,760
+prolapse أو بيصير ضغط على القناة الشوكية إيش
+
+194
+00:16:01,760 --> 00:16:04,640
+بيعملوا ال surgeon بيروحوا عند منطقة ال Lamina
+
+195
+00:16:04,640 --> 00:16:08,240
+وبيعملوا Laminectomy بيشيلوا اللامن هذي عشان
+
+196
+00:16:08,240 --> 00:16:14,740
+يريحوا الانخعوا يريحوا الـ spinal nerve اللي طبعا
+
+197
+00:16:14,740 --> 00:16:22,160
+هذا تقريبا شكل ال ال vertebra اللي بتكون بين each
+
+198
+00:16:22,160 --> 00:16:25,640
+two vertebra فى انه حاجة اسمها intervertebral disk
+
+199
+00:16:25,640 --> 00:16:31,120
+ال structure و ال function ال function يقول ال
+
+200
+00:16:31,120 --> 00:16:34,600
+disk بتكون من حاجة اسمها انهيراسوبروسس و
+
+201
+00:16:34,600 --> 00:16:39,770
+نوكياسبالبوسس هو عبارة عن مادة cartilageوفيها
+
+202
+00:16:39,770 --> 00:16:45,050
+نوعها بتعمل ك shock absorption تنفس الصدمات على ال
+
+203
+00:16:45,050 --> 00:16:51,930
+back عشان تخفف من ال risk لل fracturesطب احنا
+
+204
+00:16:51,930 --> 00:16:56,410
+بنوصف يعني ايش الفرق بين ال cervical و بين ال
+
+205
+00:16:56,410 --> 00:17:00,550
+thoracic و بين ال lumbar ال cervical هي بتحمل بس
+
+206
+00:17:00,550 --> 00:17:05,470
+ال head فهي من ناحية biomechanics الوزن اللي
+
+207
+00:17:05,470 --> 00:17:10,270
+بتحمله cervical و vertebra طبعا بتحمل بس وزن الرأس
+
+208
+00:17:10,840 --> 00:17:16,280
+الـ thoracic بتحمل وزن الرأس مع ال neck مع جزء من
+
+209
+00:17:16,280 --> 00:17:20,200
+ال trunk أما ال lumbar فبتحمل كل هدول مع ال belfry
+
+210
+00:17:20,200 --> 00:17:25,360
+الجردل مع ال thoracic أو ال pectoral girdle و ال
+
+211
+00:17:25,360 --> 00:17:30,720
+upper limb فالطبيعي احنا يتدرج حجم هذه ال vertebra
+
+212
+00:17:30,720 --> 00:17:35,520
+من أعلى إلى أسفل في اتجاه الكبرإيش؟ لأنه لو
+
+213
+00:17:35,520 --> 00:17:39,120
+تتكلمنا عن الضغط اللي بتتحمله هذه ال vertebra كل
+
+214
+00:17:39,120 --> 00:17:42,580
+ما كنا في الأسفل هتحمل وزن أكتر فهيتوزع الوزن على
+
+215
+00:17:42,580 --> 00:17:46,520
+ال area فمنطق أنها تكون أكبر عشان يكون الضغط عليها
+
+216
+00:17:46,520 --> 00:17:51,420
+أقل أو ال stress اللي هتتحمله أقل طبعا ال Atlas و
+
+217
+00:17:51,420 --> 00:17:55,560
+ال axis في ال cervical vertebra هدولة لها خصوصية
+
+218
+00:17:55,560 --> 00:18:00,080
+ال Atlas هي العضمة اللي بتيجي عليها يقعد عليها ال
+
+219
+00:18:00,080 --> 00:18:05,450
+head فهي support the headأما ال axis فهي عضلة إلها
+
+220
+00:18:05,450 --> 00:18:11,590
+زي النحور عشان تساعد على حركة الرأس إلى اليمين إلى
+
+221
+00:18:11,590 --> 00:18:16,550
+الوسار فهذه بتساعدنا على الحركة في إنها طبعا ال
+
+222
+00:18:16,550 --> 00:18:22,170
+transverse foramen اللي يفوت منه ال spinal cord
+
+223
+00:18:22,170 --> 00:18:27,270
+وفي بتتميز في إنها ال
+
+224
+00:18:29,630 --> 00:18:35,970
+الاطلاس it means انها ال spinal process فيها pivot
+
+225
+00:18:35,970 --> 00:18:41,690
+يعني زي شوكة عامل اللي هو فرعين وفي ان ال seven
+
+226
+00:18:41,690 --> 00:18:45,970
+cervical vertebra هي landmark تكون لو احنا اتحسسنا
+
+227
+00:18:45,970 --> 00:18:49,970
+في منطقة أسفل الرقبة بنلاقيها bears
+
+228
+00:18:52,260 --> 00:18:55,460
+ال science process تبعها هذه خواصة تقريبا ال
+
+229
+00:18:55,460 --> 00:19:02,400
+cervical أو مختصر لخواصة ال cervical vertebra
+
+230
+00:19:05,660 --> 00:19:09,820
+الـ thoracic vertebra فهي vertebra تقليدية لكن الـ
+
+231
+00:19:09,820 --> 00:19:14,280
+spinous process فيها أطول شوية وموجود فيها facets
+
+232
+00:19:14,280 --> 00:19:20,240
+للربب المعنى ان ال ribs هالقيتها او الرش بتيجي
+
+233
+00:19:20,240 --> 00:19:26,320
+تتسط فيها في منطقة في منطقة التهارب فهذه بس من
+
+234
+00:19:26,320 --> 00:19:29,660
+مميزاتها انها long spinous process وفيها rib
+
+235
+00:19:29,660 --> 00:19:33,420
+facets اما ال lumber فهي اكبر واحدة و اوسع واحدة
+
+236
+00:19:33,420 --> 00:19:40,630
+هي shortأول شي Large body thick تتحمل ضغط فيها
+
+237
+00:19:40,630 --> 00:19:44,750
+short spinous ال process موجود هي ليش أكبر واحدة
+
+238
+00:19:44,750 --> 00:19:50,050
+لأن هي اللي بتحمل الضغط كل ما فوقها من الجذع يعني
+
+239
+00:19:50,050 --> 00:19:54,950
+كل وزن ال trunk ال upper limbs هيكون موجود على هذه
+
+240
+00:19:54,950 --> 00:20:02,620
+المنطقة أما ال sacrum فهي عبارة عن effusionلأ خمسة
+
+241
+00:20:02,620 --> 00:20:08,340
+من ال vertebra فى عنا ميديا ال sacral الchrist
+
+242
+00:20:08,340 --> 00:20:12,460
+وعنا posterior sacral فرنن وال posterior wall of
+
+243
+00:20:12,460 --> 00:20:17,580
+the pelvic cavity هى بتكون مكوّنة من اللى هى ال
+
+244
+00:20:17,580 --> 00:20:22,480
+sacrum وفى ال sacral برمونتورى زى ما هو موضح عنا
+
+245
+00:20:22,480 --> 00:20:27,760
+بالشكل الموجودأما الكوكسيس فهي قلنا الـ tail bone
+
+246
+00:20:27,760 --> 00:20:33,260
+هي عبارة عن four fused vertebra هذه هي قلنا العضمة
+
+247
+00:20:33,260 --> 00:20:40,140
+اللي تبقى ويعاد بيها خلق الإنسان أو الحيوان مرة
+
+248
+00:20:42,370 --> 00:20:48,330
+طبعا الأكثر skeleton في through the life بيكون أول
+
+249
+00:20:48,330 --> 00:20:51,990
+ما بيبدأ ما بتبدأ ال curvature هذه بتبدأ في عينة
+
+250
+00:20:51,990 --> 00:20:57,510
+primary curvature بتبدأ في غوجنين شكله C شاب بشكل
+
+251
+00:20:57,510 --> 00:21:03,050
+حرف ال C بيبدأ يتشكل مع انمه فيبقى عينة ال sacral
+
+252
+00:21:03,050 --> 00:21:09,200
+وثوس ال curvature دولة primary بلواconvex
+
+253
+00:21:09,200 --> 00:21:12,160
+posteriorly أما ال secondary curvature زي ال
+
+254
+00:21:12,160 --> 00:21:16,980
+cervical و ال lumbar بيبدأ تشكيلهم كل ما تطورنا في
+
+255
+00:21:16,980 --> 00:21:20,580
+النمو طبعا ال cervical curvature بيبدأ من الهدراز
+
+256
+00:21:20,580 --> 00:21:24,960
+أول ما بيبدأ الطفل يرفع رأسه على هو في ال point
+
+257
+00:21:24,960 --> 00:21:28,800
+position فهو بيبدأ يشكل عنده هذا ال curve لما
+
+258
+00:21:28,800 --> 00:21:33,140
+بيمشي تبدأ تزيد ال curve لما تظهر بمظهرها اللي
+
+259
+00:21:33,140 --> 00:21:38,850
+احنا بنشوفه في ال adult moodطبعا هي كل وظيفتها
+
+260
+00:21:38,850 --> 00:21:45,690
+انها تعمل redistribution لل weight من ال upper
+
+261
+00:21:45,690 --> 00:21:51,310
+body ل ال lower limbs طبعا في انا three main curve
+
+262
+00:21:57,460 --> 00:22:01,680
+Kefosis هو إبارة عن exaggeration أو زيادة في
+
+263
+00:22:01,680 --> 00:22:07,140
+التراث الكيرفاتشار directly posteriorly بتسميها
+
+264
+00:22:07,140 --> 00:22:11,940
+humpbackback أو back lock أما ال lordosis فهي
+
+265
+00:22:11,940 --> 00:22:16,220
+مشهية ال lord بيسموها way back بيكون فيه زيادة في
+
+266
+00:22:16,220 --> 00:22:21,040
+ال number ال lordosis بيصير المظهر أنه في عندنا
+
+267
+00:22:21,040 --> 00:22:25,080
+big belly زي المرأة الحامل وفي عندنا big buttocks
+
+268
+00:22:25,080 --> 00:22:30,520
+في الخلف يعني من قدام في كرج وفي خلفيأما الـ
+
+269
+00:22:30,520 --> 00:22:33,240
+scoliosis فهي abnormal lateral curvature هذه
+
+270
+00:22:33,240 --> 00:22:37,780
+نشوفها في الـ posterior view بتطلع عندنا شكل ال
+
+271
+00:22:37,780 --> 00:22:43,660
+vertebral column مائل laterally فهذه بتكون عبارة
+
+272
+00:22:43,660 --> 00:22:47,950
+عن أحيانا بتكون structuralأو postural، الـ
+
+273
+00:22:47,950 --> 00:22:51,590
+postural بتكون ممكن تعديلها بال exercise، أما ال
+
+274
+00:22:51,590 --> 00:22:55,530
+structural فهذه بتحتاج بتاع تدخلات أخرى وهو ال
+
+275
+00:22:55,530 --> 00:22:58,510
+scoliosis the most common spinal curvature هي
+
+276
+00:22:58,510 --> 00:23:03,230
+بتنتج عن إيش؟ هي بتنتج عن مشكلة أثناء development
+
+277
+00:23:03,230 --> 00:23:08,370
+لل vertebral arch في حتى فترة ال interview أو بعد
+
+278
+00:23:10,790 --> 00:23:20,710
+هذه صورة توضحية لل .. ال .. ال handbag الثروس
+
+279
+00:23:20,710 --> 00:23:27,270
+الكاشف هو عبارة عن القفص الصدري، إيش وظيفة القفص
+
+280
+00:23:27,270 --> 00:23:33,410
+الصدري؟ إنه يحمي ال vital organs زي ال heart و ال
+
+281
+00:23:33,410 --> 00:23:38,520
+lungs، the trachea و ال oesophagusطبعا هدولة بدهم
+
+282
+00:23:38,520 --> 00:23:42,060
+بيحتاجوا protection طيب ال thoracic cage من إيش
+
+283
+00:23:42,060 --> 00:23:46,040
+بتكون؟ بتكون من ال rib، عن ال sternum و من الباك
+
+284
+00:23:46,040 --> 00:23:50,580
+ال thoracic vertebra طبعا في إن عضلات التنفس بتكون
+
+285
+00:23:50,580 --> 00:23:59,400
+كلها مثبتة في هذا ال .. في ال rib cageوكمان فى ان
+
+286
+00:23:59,400 --> 00:24:02,700
+عضلات اللى هى ال pectoral girdle و ال chest تكونك
+
+287
+00:24:02,700 --> 00:24:06,120
+و ال shoulder و ال back musculatures دايما بتكون
+
+288
+00:24:06,120 --> 00:24:10,300
+involved فى ال respiration طبعا هذا شكله فى هنا
+
+289
+00:24:10,300 --> 00:24:15,870
+عددمن واحد ما سبعة من ال ribs بنسميهم true ribs
+
+290
+00:24:15,870 --> 00:24:20,250
+وفي عندنا ال false ribs لإنها هي ليش true ribs
+
+291
+00:24:20,250 --> 00:24:24,410
+هلقيتها هنقول ليش لإن هدولة كل واحدة من ال ribs ع
+
+292
+00:24:24,410 --> 00:24:28,630
+طريق ال crustal cartilage بتكون إلها attachmentمع
+
+293
+00:24:28,630 --> 00:24:32,730
+الsterna اما ال first rib اللي هم من تمانية تقريبا
+
+294
+00:24:32,730 --> 00:24:37,030
+ال 12 في منهم ال 11 و 12 هدولة floating مالهونش اي
+
+295
+00:24:37,030 --> 00:24:40,770
+attachment مع اي اشي و هم مش coastal cartilage اما
+
+296
+00:24:40,770 --> 00:24:47,090
+من تمانية لعشرة فهم كلهم مع بعض attached في one
+
+297
+00:24:47,090 --> 00:24:51,510
+attachment او coastal cartilage واحد في الsterna
+
+298
+00:24:55,430 --> 00:24:59,490
+زي ما هنا شرحنا على الرسمة بنعيد الكلام أما ال
+
+299
+00:24:59,490 --> 00:25:04,170
+floating grip فهي مش ماعندهاش اي connection مع
+
+300
+00:25:04,170 --> 00:25:10,510
+السيرم هي floating عائمة وهذا
+
+301
+00:25:10,510 --> 00:25:20,880
+شكل ال rib كل rib بيكون فيهاتلتقي مع الـ sternum و
+
+302
+00:25:20,880 --> 00:25:25,800
+كمان من الناحية الأخرى تلتقي مع ال .. من الخلف مع
+
+303
+00:25:25,800 --> 00:25:32,400
+ال vertebra و بهيك احنا بنكون خلصنا و حديثنا عن ال
+
+304
+00:25:32,400 --> 00:25:35,880
+axial skeleton و المحاضرة القادمة تكون عن ال
+
+305
+00:25:35,880 --> 00:25:39,020
+perpendicular skeleton، يعطيكم العافية
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk.srt
new file mode 100644
index 0000000000000000000000000000000000000000..3cb64e00b2269b6eae22c0e9716fd31ad0af92dc
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk.srt
@@ -0,0 +1,975 @@
+1
+00:00:04,930 --> 00:00:11,110
+بسم الله الرحمن الرحيم محاضرتنا اليوم الخامسة في
+
+2
+00:00:11,110 --> 00:00:16,270
+مجل ال anatomy، Introduction to anatomy، or
+
+3
+00:00:16,270 --> 00:00:20,630
+essential human anatomy. راح نتكلم اليوم عن ال skin
+
+4
+00:00:22,360 --> 00:00:28,540
+تقريبا ال skin يعتبر هو ال integumentary system of
+
+5
+00:00:28,540 --> 00:00:32,120
+the body، و هو largest تقريبا organ of the body
+
+6
+00:00:32,120 --> 00:00:38,380
+مساحته بيجي في المتوسط من one point six or one point
+
+7
+00:00:38,380 --> 00:00:42,140
+nine، يعني حوالي اتنين متر مربع، من متر ونصف إلى اتنين
+
+8
+00:00:42,140 --> 00:00:50,650
+متر مربع، an average size of adults، لأن ال skin هو
+
+9
+00:00:50,650 --> 00:00:58,030
+عبارة عن الغطاء تبع الجسم، اللي تحته تندرج كل ال
+
+10
+00:00:58,030 --> 00:01:02,510
+organs. Integumentary system describes the skin and
+
+11
+00:01:02,510 --> 00:01:09,390
+its appendages، ملحقاته، يعني ال skin و ملحقاته كلهم
+
+12
+00:01:09,390 --> 00:01:14,640
+مع بعض بنسميهم ال integumentary system. في عندنا
+
+13
+00:01:14,640 --> 00:01:19,260
+نوعين من ال skin: في عندنا ال thin skin اللي موجود
+
+14
+00:01:19,260 --> 00:01:25,800
+على معظم أجزاء الجسم، ما عدا ال dorsum of the
+
+15
+00:01:25,800 --> 00:01:29,720
+hand and the foot. وفي عندنا ال thick skin، الخامل
+
+16
+00:01:29,720 --> 00:01:34,100
+اللي هو موجود في ال palm and plantar surface of
+
+17
+00:01:34,100 --> 00:01:37,340
+the foot. طبعا ال thickness بتتراوح من واحد
+
+18
+00:01:37,340 --> 00:01:44,020
+إلى ثلاثة مليمترات. في ال thin skin و كمان من أربعة
+
+19
+00:01:44,020 --> 00:01:46,380
+إلى خمسة مليمترات في ال thick skin.
+
+20
+00:01:50,920 --> 00:01:54,920
+بالنسبة للـ function، نعرف أنه الـ function of the
+
+21
+00:01:54,920 --> 00:02:01,440
+skin، عبارة عن.. تعلمنا من بداية حياتنا، حتى لما كنا أطفال في
+
+22
+00:02:01,440 --> 00:02:06,280
+المدارس، كانوا بيقولوا أن الجلد هو خط الدفاع الأول عن
+
+23
+00:02:06,280 --> 00:02:13,300
+الجسم. يبقى هو من وظائفه هو ال protection، كمان
+
+24
+00:02:13,300 --> 00:02:15,640
+regulation of temperature،
+
+25
+00:02:19,240 --> 00:02:23,000
+excretion، بيفرز العرق. إحنا لما بيطلع العرق على
+
+26
+00:02:23,000 --> 00:02:28,700
+الجسم، بيطلع على سطح الجسم عن طريق ال skin، و synthesis of
+
+27
+00:02:28,700 --> 00:02:32,280
+vitamin D. بنعرف أنه إحنا لما نتعرض للشمس، للشمس
+
+28
+00:02:32,280 --> 00:02:40,360
+بيصير في عندنا إفراز لهرمون، أو لفيتامين D، المهم
+
+29
+00:02:40,360 --> 00:02:45,680
+كتير في عملية امتصاص الكالسيوم والبوتاسيوم، وكمان ال
+
+30
+00:02:45,680 --> 00:02:49,800
+immune system، هو ال first defense barrier of the
+
+31
+00:02:49,800 --> 00:02:55,440
+immune system. يبقى نرجع نقول أن ال skin بيقدم لي
+
+32
+00:02:55,440 --> 00:02:59,930
+أكثر من function، منها temperature regulation، منها
+
+33
+00:02:59,930 --> 00:03:06,850
+protection، بمنع كمان ال.. بيحافظ على الجلد وعلى
+
+34
+00:03:06,850 --> 00:03:12,430
+الرطوبة، بمنع السوائل إنها تطلع، وفي نفس الوقت بيعطيني
+
+35
+00:03:12,430 --> 00:03:16,650
+إحساس، و هذا كتير مهم لل sensory. أنا بالنسبة لي، إذا
+
+36
+00:03:16,650 --> 00:03:20,890
+حطيت إيدي هنا، بقدر أحس إذا كان هذا السطح بارد أو
+
+37
+00:03:20,890 --> 00:03:25,450
+ساخن، إذا كان في شوكة، أو في إبرة، أو في دبوس، بحس إنه، الإحساس
+
+38
+00:03:25,450 --> 00:03:30,990
+المنتشَر على كل الجلد، هذا بيخليني.. بيعمل لي alerts،
+
+39
+00:03:30,990 --> 00:03:34,050
+بينبهني: "دير بالك، أنت اتعرضت لبيئة ساخنة، اتعرضت لـ"
+
+40
+00:03:34,050 --> 00:03:37,390
+"بيئة باردة"، كل هذا عن طريق الإحساس. دعست على
+
+41
+00:03:37,390 --> 00:03:42,310
+مسمار، مسكت مقبض ساخن، هذا كله من
+
+42
+00:03:42,310 --> 00:03:43,590
+ال skin.
+
+43
+00:03:45,370 --> 00:03:49,590
+يبقى في ال protection، إيش بدنا نقول في الموضوع ال
+
+44
+00:03:49,590 --> 00:03:53,670
+skin protection؟ عبارة عن physical barrier from
+
+45
+00:03:53,670 --> 00:04:01,130
+microorganisms، بيمنع دخول أي شيء إلى داخل الجسم،
+
+46
+00:04:01,130 --> 00:04:06,720
+حاجز. إذا كنا اتعرضنا لمواد كيميائية، إذا كان
+
+47
+00:04:06,720 --> 00:04:11,200
+استخدمنا ماء نار، إيجى على إيدنا أي شيء ساخن، أي
+
+48
+00:04:11,200 --> 00:04:16,620
+شيء chemical، ممكن يعمل إيه؟ يدخل للجسم، فال skin
+
+49
+00:04:16,620 --> 00:04:19,540
+هذا بيوقفه عند حدوده و بيمنعه.
+
+50
+00:04:22,120 --> 00:04:27,200
+يعني إحنا لما بنخبط، وإحنا ماشيين، أو إحنا ماشيين
+
+51
+00:04:27,200 --> 00:04:31,780
+في حافة الطاولة، أو في حافة الكرسي، ال skin هذا عامل
+
+52
+00:04:31,780 --> 00:04:35,040
+زي المخدة كده، على الأشياء، بطريقة  subcutaneous
+
+53
+00:04:35,040 --> 00:04:38,880
+الـ structures اللي موجودة فيه، بيمنع ال mechanical trauma،
+
+54
+00:04:38,880 --> 00:04:41,720
+prevent dehydration، بيمنع السوائل، و excessive
+
+55
+00:04:41,720 --> 00:04:45,920
+secretions، بيمنعها إنها تطلع، فبيمنع الجفاف. protect
+
+56
+00:04:46,650 --> 00:04:50,690
+from excessive ultraviolet exposure. طبعا
+
+57
+00:04:50,690 --> 00:04:53,790
+إحنا اللي بنبقى متعرضين لأشعة الشمس، بنبقى ماشيين جلدنا
+
+58
+00:04:53,790 --> 00:04:57,910
+كله مكشوف، إلا من فضل ربنا. يعني إحنا النساء المسلمات، بيكون
+
+59
+00:04:57,910 --> 00:05:02,190
+جسمهن مستور، ما عدا الوجه والكفين. والحكمة من كشف
+
+60
+00:05:02,190 --> 00:05:07,570
+الوجه والكفين، هو أن أكتر مناطق ممكن أنها تعمل synthesis،
+
+61
+00:05:07,570 --> 00:05:10,450
+وتعرضها للشمس يعمل
+
+62
+00:05:10,450 --> 00:05:16,230
+synthesis للفيتامين D، هي اليدين والوجه. لكن
+
+63
+00:05:16,230 --> 00:05:20,650
+الجسم إذا اتعرض لـ excessive sun light، ممكن يتعرض
+
+64
+00:05:20,650 --> 00:05:28,330
+لـ burn. لكن الجلد هو اللي بيحمي الجسم من ال sun burn.
+
+65
+00:05:28,330 --> 00:05:33,150
+أما ال function التانية، فهي ال sensation، ال
+
+66
+00:05:33,150 --> 00:05:37,730
+sensation اللي إنتِ بتشعريه، بواسطة ال sensory organs
+
+67
+00:05:37,730 --> 00:05:47,650
+أو بواسطة ال tactile tissues، اللي بتخلينا نحس بكل شيء
+
+68
+00:05:47,650 --> 00:05:52,110
+ممكن إحنا نتعرض له. نتعرض له، somatic sensory
+
+69
+00:05:52,110 --> 00:05:57,490
+receptors detect stimuli that permit us to detect ال
+
+70
+00:05:57,490 --> 00:06:01,970
+pressure، ال touch، ال temperature، ال pain، all the
+
+71
+00:06:01,970 --> 00:06:05,550
+general sensations. يعني إحنا لو مسكنا، وإحنا
+
+72
+00:06:05,550 --> 00:06:10,470
+مغمضين، بيدنا شيء، بنحس بمسكنا قلم، بنعرف إنه هذا
+
+73
+00:06:10,470 --> 00:06:13,470
+قلم، مسكنا الجوال، هذا جوالي ولا مش جوالي، حتى وإنا
+
+74
+00:06:13,470 --> 00:06:17,430
+مش شايفه، آه بعرف، لأني عارف حجم جوالي وشكله. كل
+
+75
+00:06:17,430 --> 00:06:22,190
+الإحساس بيصير عن طريق ال skin. لو وقع على رجلنا شيء،
+
+76
+00:06:22,190 --> 00:06:25,290
+طبعا الناس اللي بتفقد الإحساس هذه بتكون عرضة أكثر
+
+77
+00:06:25,290 --> 00:06:31,190
+للـ injury، كمان.
+
+78
+00:06:31,190 --> 00:06:36,110
+ال skin فيه خاصية ال flexibility، وهي بتساعد على ال
+
+79
+00:06:36,110 --> 00:06:40,150
+elasticity، هذه بتساعد على تغيير الشكل. يعني أنا بدي
+
+80
+00:06:40,150 --> 00:06:43,150
+أغلق إيدي، بدي أفتح إيدي، لو إن ال skin عندي
+
+81
+00:06:43,150 --> 00:06:47,110
+flexible. كان أنا ما أقدرش أغلق إيدي. لو افترضنا أن شخص
+
+82
+00:06:47,110 --> 00:06:51,400
+أخذ مثلا جروح حارقة، عنده جروح في هذه المنطقة، بيصير
+
+83
+00:06:51,400 --> 00:06:56,060
+فرد إيده هذه صعب، ليش؟ لأنه بيصير ال skin مش
+
+84
+00:06:56,060 --> 00:06:59,300
+flexible. فمعناه أني أنا، الحركات اللي بعملها هذه
+
+85
+00:06:59,300 --> 00:07:02,440
+كلها، اللي بيسمح لي فيها، اللي بيعطيني ال range فيها
+
+86
+00:07:02,440 --> 00:07:07,820
+هو صحيح المدى العضلي، لكن كمان ال skin flexibility of
+
+87
+00:07:07,820 --> 00:07:11,060
+the skin. و ال excretions، اللي هي ال water، و ال
+
+88
+00:07:11,060 --> 00:07:14,340
+urea، و كل الأشياء، السموم اللي بتطلع عن طريق ال
+
+89
+00:07:14,340 --> 00:07:18,980
+sweat، هذه بتخلص منها الجسم. نتكلم عن ال sweating
+
+90
+00:07:18,980 --> 00:07:24,460
+glands، هي تقريبا مكيف الجسم، اللي بيخلي الجسم يتعرق،
+
+91
+00:07:24,460 --> 00:07:29,700
+فبيقلل من حرارة الجسم الداخلية. ال immune، ليش؟ لأن
+
+92
+00:07:29,700 --> 00:07:33,720
+في عندنا حاجة اسمها Langerhans cells، هذه طبيعتها
+
+93
+00:07:33,720 --> 00:07:38,900
+بتساعد في ال immune system، فهي فيها ال phagocytosis، أو
+
+94
+00:07:38,900 --> 00:07:43,480
+ال phagocytic cells، بتعمل destroying للبكتيريا. نلاحظ أن
+
+95
+00:07:43,480 --> 00:07:47,040
+إحنا أول ما بنصاب بجرح، أو خدش، بتبدأ عندنا الحمرة، و
+
+96
+00:07:47,040 --> 00:07:52,500
+بتبدأ تصير في عملية هجوم من ال white blood cells
+
+97
+00:07:52,500 --> 00:07:57,840
+في المكان، حتى إنها تمنع دخول البكتيريا وتخلص منها.
+
+98
+00:08:00,240 --> 00:08:05,300
+طبعا الـ heat loss، تقريبا إحنا 80% of heat loss
+
+99
+00:08:05,300 --> 00:08:08,960
+occurs through the skin، لأن الجسم إذا كان في جو
+
+100
+00:08:08,960 --> 00:08:12,960
+حار زي هيك، بيحتفظ بالحرارة، بيحتفظ بالحرارة، بعد
+
+101
+00:08:12,960 --> 00:08:17,920
+هيك إيش بيصير؟ خلينا نقول بالعربي: بتنتفخ الأعضاء،
+
+102
+00:08:17,920 --> 00:08:20,780
+يعني مش معقول إنهم يتحملوا ارتفاع مستمر في درجات
+
+103
+00:08:20,780 --> 00:08:25,340
+الحرارة، فالجسم بيخلص ال.. ال heat، بيخلص الجسم من
+
+104
+00:08:25,340 --> 00:08:30,470
+الحرارة عن طريق ال sweating. بضمن 20% occurred
+
+105
+00:08:30,470 --> 00:08:33,830
+through the mucous membranes، والـ respiratory، والـ digestive،
+
+106
+00:08:33,830 --> 00:08:38,310
+و الـ urinary tracts. أما ال skin بياخد 80% من التخلص
+
+107
+00:08:38,310 --> 00:08:44,110
+الجسم من الحرارة الزائدة.  في شيء مهم كتير في
+
+108
+00:08:44,110 --> 00:08:47,970
+عندنا: three layers of skin. هذا ال skin اللي إحنا
+
+109
+00:08:47,970 --> 00:08:52,550
+شايفينه، اللي بنمسكه، سواء كان رقيق أو كان خامل، فهو
+
+110
+00:08:52,550 --> 00:08:56,430
+بيكون من ثلاثة layers، اثنين منهم هي layers of skin،
+
+111
+00:08:56,430 --> 00:08:59,570
+و ال layer اللي هو subcutaneous layer، هو
+
+112
+00:08:59,570 --> 00:09:03,770
+أحيانًا ما بيعتبر، هو دائمًا بيعتبر part of the skin.
+
+113
+00:09:03,770 --> 00:09:06,850
+يبقى في عندنا ال epidermis، في عندنا ال dermis، في
+
+114
+00:09:06,850 --> 00:09:11,290
+عندنا subcutaneous layers. ال subcutaneous، اللي هو
+
+115
+00:09:11,290 --> 00:09:16,470
+sub، كلمة sub دائمًا تعني تحت، تحت الجلد، طبقة من
+
+116
+00:09:16,470 --> 00:09:20,450
+الدهون، بتكون تحت الجلد، يبقى beneath the dermis، not
+
+117
+00:09:20,450 --> 00:09:26,930
+part of the skin. زي ما إحنا شايفين، هذا الشكل هنوضح
+
+118
+00:09:26,930 --> 00:09:31,030
+أكثر، ونتعرف على ال epidermis. كلمة epidermis means
+
+119
+00:09:31,030 --> 00:09:36,670
+على، فوق، above، اللي فوق، الطبقة الخارجية. طبعا الطبقة
+
+120
+00:09:36,670 --> 00:09:40,830
+الخارجية، بتكون ما فيهاش blood vessels، keratinized،
+
+121
+00:09:40,830 --> 00:09:45,530
+فيها ال protein، ال keratin.  thickenest on the palm
+
+122
+00:09:45,530 --> 00:09:48,670
+and the sole. قلنا في عندنا نوعين من ال skin، في
+
+123
+00:09:48,670 --> 00:09:51,530
+عندنا thick skin، وفي عندنا thin skin. ال thick
+
+124
+00:09:51,530 --> 00:09:57,390
+skin بيكون في palm of the foot and the sole of the
+
+125
+00:09:57,390 --> 00:10:04,390
+palm of the hand and the sole of the foot. الـ
+
+126
+00:10:04,390 --> 00:10:08,090
+melanocytes provide melanin. الـ melanin هو الصبغة
+
+127
+00:10:08,090 --> 00:10:13,570
+اللي بتحدد، يعني بيكون على أثرها تركيزها، نوع لون ال
+
+128
+00:10:13,570 --> 00:10:17,750
+skin. إذا كان هذا بشرته بيضاء، هذا بشرته سمراء، هذا
+
+129
+00:10:17,750 --> 00:10:21,890
+بشرته أسمر، هذا بشرته سوداء، بيكون تركيز ال melanin
+
+130
+00:10:21,890 --> 00:10:26,610
+فيها أكثر. طبعا في حاجة اسمها Basal، أو Basement
+
+131
+00:10:26,610 --> 00:10:30,610
+Membrane. اتكلمنا على ال epithelial cells في المرات
+
+132
+00:10:30,610 --> 00:10:34,780
+السابقة. ال epithelial cells، قلنا إن اللي بتبقى الأخيرة، أو
+
+133
+00:10:34,780 --> 00:10:38,080
+التحتانية، هي عبارة عن Basal cells، أو بنسميها
+
+134
+00:10:38,080 --> 00:10:44,480
+basement. ونوع ال epithelial cells اللي موجودة
+
+135
+00:10:44,480 --> 00:10:52,460
+stratified squamous، لأنها هي شكلها كده مسطح. طبعا
+
+136
+00:10:52,460 --> 00:10:58,180
+في عندنا أنواع الـ cells اللي بتكون ال epidermis، في
+
+137
+00:10:58,180 --> 00:11:02,140
+عندنا ال keratinocytes، وال melanocytes، و ال Langerhans
+
+138
+00:11:02,140 --> 00:11:08,880
+cells. كل واحدة منهم لها وظيفة. ال keratinocytes عبارة عن 90%
+
+139
+00:11:08,880 --> 00:11:12,760
+من هذه ال cells، اللي موجودة، ال principle structure
+
+140
+00:11:12,760 --> 00:11:17,860
+element for outer skin، بتكون الطبقة الخارجية من ال
+
+141
+00:11:17,860 --> 00:11:21,660
+skin. أما ال melanocytes، هي ال pigmentation، اللي بتعمل
+
+142
+00:11:21,660 --> 00:11:27,260
+لون الجلد، products producing 5% of the total
+
+143
+00:11:27,260 --> 00:11:31,840
+contribute and scale color filter ال ultraviolet
+
+144
+00:11:31,840 --> 00:11:37,100
+light، هي اللي بتساعد على الحفاظ على الجلد من ال
+
+145
+00:11:37,100 --> 00:11:41,720
+ultraviolet اللي بتجينا من الشمس. Langerhans cells هي
+
+146
+00:11:41,720 --> 00:11:45,180
+ال dendritic branches، عبارة عن antigen
+
+147
+00:11:45,180 --> 00:11:51,700
+-presenting cells، ال ABCs، they play a role in
+
+148
+00:11:51,700 --> 00:11:56,380
+immune response. إذا تعرض الجسم، أو الجلد لأي insult،
+
+149
+00:11:56,380 --> 00:12:02,700
+يعني insect مثلا،  عضتنا نحلة، عضتنا أي insect،
+
+150
+00:12:02,700 --> 00:12:07,970
+اجت وقرصتنا، فعلى طول بتشتغل Langerhans cells، وبتعمل إيه؟
+
+151
+00:12:07,970 --> 00:12:13,550
+بتزود المناعة في هذا المكان. أما ال epidermis كمان
+
+152
+00:12:13,550 --> 00:12:17,190
+بتكون من layers، يعني هي طبقة رقيقة صحيح، لكن بتكون
+
+153
+00:12:17,190 --> 00:12:21,430
+من layers. في حالة ال thick skin بتكون خمسة layers،
+
+154
+00:12:21,430 --> 00:12:25,670
+في حالة ال thin skin بتكون أربعة layers. ال layers
+
+155
+00:12:25,670 --> 00:12:32,750
+هذه، عبارة عن، لو أخدناها من السطح للأسفل، فعندنا ال
+
+156
+00:12:32,750 --> 00:12:38,220
+stratum corneum، و ال stratum lucidum، و ال stratum
+
+157
+00:12:38,220 --> 00:12:43,200
+granulosum، و ال stratum spinosum، و ال basal. ناخذهم واحدة واحدة
+
+158
+00:12:43,200 --> 00:12:54,440
+ونتعرف عليهم الآن. ال basal
+
+159
+00:12:54,440 --> 00:12:59,430
+stratum، الطبقة القاعدية، إحنا بنسميها، عبارة عن
+
+160
+00:12:59,430 --> 00:13:02,970
+single layer columnar. إيش يعني columnar؟ يعني شكل
+
+161
+00:13:02,970 --> 00:13:07,950
+ال cells بهذا الشكل. هي طبقة واحدة، لكن ال cells
+
+162
+00:13:07,950 --> 00:13:13,790
+columnar، تمام؟
+
+163
+00:13:17,090 --> 00:13:20,870
+زي ما اتعرفنا في محاضرتنا تبع الـ Epithelium،
+
+164
+00:13:20,870 --> 00:13:27,490
+columnar cells. under mitosis، و migration، بتنقسم
+
+165
+00:13:27,490 --> 00:13:35,650
+و بتروح، بتهاجر، حتى تصل للسطح وتموت. أما الـ stratum spinosum، ال
+
+166
+00:13:35,650 --> 00:13:42,360
+stratum spinosum، اللي هي spiny layer، cells are
+
+167
+00:13:42,360 --> 00:13:46,560
+arranged in eight to ten rows. يعني هنا الأول layer
+
+168
+00:13:46,560 --> 00:13:50,240
+الأولاني، أو ال base، بتكون من layer واحد. أما ال
+
+169
+00:13:50,240 --> 00:13:55,800
+layer الثاني، بتكون من eight to ten layers.
+
+170
+00:13:58,910 --> 00:14:03,590
+شكلها بيكون عامل زي ال spine، يعني بيكون مبوّظ كده،
+
+171
+00:14:03,590 --> 00:14:09,770
+spinous، تمام؟ into spiny shape، cells rich in RNA.
+
+172
+00:14:09,770 --> 00:14:16,190
+فيها ال RNA. أما ال granulosum، أو ال stratum
+
+173
+00:14:18,430 --> 00:14:22,890
+granulosum، cells arranged in two to four layers، filled with
+
+174
+00:14:22,890 --> 00:14:27,930
+keratin granules.  هي ليه؟  keratin granules contains high level of
+
+175
+00:14:27,930 --> 00:14:35,910
+lysosomal enzymes، lysosomal enzymes. أما ال stratum
+
+176
+00
+
+223
+00:18:34,760 --> 00:18:38,260
+lie muscles هي اللي بتعمل contraction فبيوقف،
+
+224
+00:18:38,260 --> 00:18:42,620
+contraction فبيوقف شعر الجسم Sensory receptors
+
+225
+00:18:42,620 --> 00:18:46,640
+موجودة فيها sweating and sebaceous glands اللي موجودة
+
+226
+00:18:46,640 --> 00:18:54,170
+فيها الـ glands الدهنية، الـ Blood vessels rich vascular
+
+227
+00:18:54,170 --> 00:18:56,790
+supply plays a critical role in temperature
+
+228
+00:18:56,790 --> 00:19:00,470
+regulation طيب واحنا قلنا كل ما كان فيه blood
+
+229
+00:19:00,470 --> 00:19:04,330
+supply أكثر كل ما كان الجسم/الجلد أسخن. طب عن الـ
+
+230
+00:19:04,330 --> 00:19:07,190
+layers؟ احنا بنتكلم عن two layers: الـ papillary layer
+
+231
+00:19:07,190 --> 00:19:12,230
+و الـ reticular layer. الـ papillary layer composed of
+
+232
+00:19:12,230 --> 00:19:15,790
+dermal papillae that project into epidermis
+
+233
+00:19:17,070 --> 00:19:21,450
+contains collagen and elastin. الـ collagen بيعطي
+
+234
+00:19:21,450 --> 00:19:25,930
+strength و الـ elastin بيعطي مرونة. الـ collagen
+
+235
+00:19:25,930 --> 00:19:31,770
+لأنه fibers و fibers قوية، فهي بتعطي الـ strength
+
+236
+00:19:31,770 --> 00:19:36,130
+للـ skin، بتقويه. أما الـ elastic fibers بتعطيني
+
+237
+00:19:36,130 --> 00:19:39,970
+المرونة عشان أنا أقدر أغمض وأفتح وأمد إيدي، و
+
+238
+00:19:39,970 --> 00:19:44,150
+أرفعها، أنزلها، وأقوم بكل الحركات اللي إحنا بنعملها.
+
+239
+00:19:44,370 --> 00:19:49,750
+contains the dermal-epidermal junction for unique
+
+240
+00:19:49,750 --> 00:19:53,110
+pattern that gives individual fingerprints. عارفين
+
+241
+00:19:53,110 --> 00:19:56,090
+الـ fingers؟ احنا كل واحد فينا بصمة على
+
+242
+00:19:56,090 --> 00:20:03,810
+الأصابع، كل جسم له بصمة. الـ reticular layer عبارة عن
+
+243
+00:20:03,810 --> 00:20:08,910
+densely interlaced يعني هي عبارة عن fibers،
+
+244
+00:20:08,910 --> 00:20:14,070
+collagenous fibers لكنها متشابكة وسميكة، and
+
+245
+00:20:14,070 --> 00:20:17,970
+elastic fibers to make the skin tough and
+
+246
+00:20:17,970 --> 00:20:24,190
+stretchable. يعني بتخلينا يكون الـ skin في إمكانية
+
+247
+00:20:24,190 --> 00:20:28,810
+للتمدد، عشان يتمدد لازم يكون فيه نوع من المرونة.
+
+248
+00:20:29,780 --> 00:20:35,600
+في حاجة اسمها lines of cleavage، lines of cleavage
+
+249
+00:20:35,600 --> 00:20:42,380
+عبارة عن خطوط موجودة في الـ skin بتحدد الـ skin
+
+250
+00:20:42,380 --> 00:20:45,860
+identifying the predominant orientation of
+
+251
+00:20:45,860 --> 00:20:50,000
+collagen fibers clinically and surgically
+
+252
+00:20:50,000 --> 00:20:53,240
+significant because a cut can result in slow
+
+253
+00:20:53,240 --> 00:20:58,340
+healing and increased scarring. تطلع على الصورة اللي
+
+254
+00:20:58,340 --> 00:21:04,520
+قدامنا، بنلاقي إن الـ cleavage lines موجودة طولية
+
+255
+00:21:04,520 --> 00:21:12,160
+هنا في الـ upper and lower limbs، وموجودة عرضية في الـ
+
+256
+00:21:12,160 --> 00:21:20,080
+trunk. طيب، إيه فائدتها لو صار cut في اتجاه
+
+257
+00:21:21,690 --> 00:21:26,790
+الـ fibers بيكون سهل الالتئام، لكن لو صار cuts
+
+258
+00:21:26,790 --> 00:21:31,850
+perpendicular فـ
+
+259
+00:21:31,850 --> 00:21:37,110
+بيصير صعب الالتئام، بيصير scarring، بيصير scar. فهذه
+
+260
+00:21:37,110 --> 00:21:43,120
+مهمة كتير للـ surgeon أنه يعرف اتجاه الـ lines هذه
+
+261
+00:21:43,120 --> 00:21:47,860
+حتى يساعدوا في اتخاذ القرار في أي اتجاه هو يفتح
+
+262
+00:21:47,860 --> 00:21:51,960
+طولياً ولا عرضياً. طبعاً، كل ما كان في اتجاه الـ collagen
+
+263
+00:21:51,960 --> 00:21:59,570
+fibers كل ما كان الـ healing أسرع وأفضل. الـ dermis
+
+264
+00:21:59,570 --> 00:22:06,270
+may leave a scar، و الـ dermal growth and repair، الـ
+
+265
+00:22:06,270 --> 00:22:11,690
+dermis regenerates itself as does the epidermis. يعني
+
+266
+00:22:11,690 --> 00:22:16,350
+بيصير regeneration للـ epidermis.
+
+267
+00:22:16,350 --> 00:22:22,010
+في عندنا الـ subcutaneous layer. الـ subcutaneous
+
+268
+00:22:22,010 --> 00:22:29,380
+layer عبارة عن طبقة، الـ dermis بتعمل زي فَاصِل،
+
+269
+00:22:29,380 --> 00:22:35,820
+بنسميها hypodermis، عبارة عن loose connective tissue،
+
+270
+00:22:35,820 --> 00:22:40,920
+adipose، insulates، and contains blood vessels بتمر
+
+271
+00:22:40,920 --> 00:22:46,980
+فيها، فيها خلايا دهنية وكمان بتعمل عملية عزل وفصل
+
+272
+00:22:46,980 --> 00:22:52,180
+بين الـ subcutaneous بين الـ dermis و الـ layers
+
+273
+00:22:52,180 --> 00:22:53,340
+اللي تحتها.
+
+274
+00:22:56,680 --> 00:22:59,480
+الـ hypodermis also called subcutaneous layer or
+
+275
+00:22:59,480 --> 00:23:03,100
+superficial fascia، لأنه في عندنا deep fascia. الـ
+
+276
+00:23:03,100 --> 00:23:06,720
+superficial fascia اللي بتكون تحت الـ skin على طول
+
+277
+00:23:06,720 --> 00:23:12,400
+هي عبارة عن  طبقة  تغطي الجسم من الجمجمة لحد
+
+278
+00:23:12,400 --> 00:23:18,460
+الـ lower limbs، forming. عندنا deep to the dermis، تحت
+
+279
+00:23:18,460 --> 00:23:22,200
+الـ dermis، forming connection between the skin and
+
+280
+00:23:22,200 --> 00:23:27,210
+other structures. هي it's not part of the skin طبعاً.
+
+281
+00:23:27,210 --> 00:23:31,950
+احنا الصورة هذه بتوضح طبقات
+
+282
+00:23:31,950 --> 00:23:37,490
+الـ epidermis جميعها،
+
+283
+00:23:37,490 --> 00:23:43,450
+وكمان بتوضحلي الـ dermis بالتفصيل وكمان الـ
+
+284
+00:23:43,450 --> 00:23:52,450
+subcutaneous اللي هتكون تحت هنا. بنشوف مكوناتها: في عندنا
+
+285
+00:23:52,450 --> 00:23:57,050
+dead keratinocytes، في عندنا stratum corneum هنا،
+
+286
+00:23:57,050 --> 00:24:04,610
+شايفينها. عندنا الـ granulosum، وعندنا الـ
+
+287
+00:24:04,610 --> 00:24:10,050
+spinosum أو الـ spinosome، وعندنا الـ basal layer. هذه
+
+288
+00:24:10,050 --> 00:24:14,450
+الطبقة اللي قلنا هي عبارة عن طبقة من الـ
+
+289
+00:24:14,450 --> 00:24:21,030
+columnar cells  اللي فوق الـ dermis، الطبقة اللي تحتها. هذه
+
+290
+00:24:21,030 --> 00:24:24,870
+مكونات طبقاتها.
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..2766285d211b4e5f598a85b93f1d56fe486bba39
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk_postprocess.srt
@@ -0,0 +1,1160 @@
+1
+00:00:04,930 --> 00:00:11,110
+بسم الله الرحمن الرحيم محاضرتنا اليوم الخامسة في
+
+2
+00:00:11,110 --> 00:00:16,270
+مجل ال anatomy introduction to anatomy or
+
+3
+00:00:16,270 --> 00:00:20,630
+essential human anatomy راح نتكلم اليوم عن ال skin
+
+4
+00:00:22,360 --> 00:00:28,540
+تقريبا ال skin يعتبر هو ال antigumentary system of
+
+5
+00:00:28,540 --> 00:00:32,120
+the body و ال largest تقريبا organ of the body
+
+6
+00:00:32,120 --> 00:00:38,380
+طوله بيجي في المتوسط من one point six or one point
+
+7
+00:00:38,380 --> 00:00:42,140
+nine يعني حوالي اتنين متر مربع من متر و نصف لاتنين
+
+8
+00:00:42,140 --> 00:00:50,650
+متر مربعan average size of adults لأن ال skin هو
+
+9
+00:00:50,650 --> 00:00:58,030
+عبارة عن الغطاء تبع الجسم اللى تحتى تندرج كل ال
+
+10
+00:00:58,030 --> 00:01:02,510
+organs Integumentary system describe the skin and
+
+11
+00:01:02,510 --> 00:01:09,390
+its appendages ملحقاته يعني ال skin و ملحقاته كلهم
+
+12
+00:01:09,390 --> 00:01:14,640
+مع بعض بنسميهم ال integumentary systemفي عندنا
+
+13
+00:01:14,640 --> 00:01:19,260
+نوعين من ال skin في عندنا ال thin skin اللى موجود
+
+14
+00:01:19,260 --> 00:01:25,800
+على معظم أجزاء الرسم لما فيها ال dorsum of the
+
+15
+00:01:25,800 --> 00:01:29,720
+hand and the foot وفي عندنا ال thick skin الخميل
+
+16
+00:01:29,720 --> 00:01:34,100
+اللى هو موجود في ال palm and plantar surface of
+
+17
+00:01:34,100 --> 00:01:37,340
+the foot طبعا ال thickness بترا واحد تن من واحد
+
+18
+00:01:37,340 --> 00:01:44,020
+لتلاتة مليو ال .. فيه thin skin و كمان من أربع
+
+19
+00:01:44,020 --> 00:01:46,380
+لخمسة ملي فيه thick skin
+
+20
+00:01:50,920 --> 00:01:54,920
+بالنسبة للـ function نعرف أنه الـ function of the
+
+21
+00:01:54,920 --> 00:02:01,440
+skin عبارة اتعلمنا من بداية حتى لما كنا أطفال في
+
+22
+00:02:01,440 --> 00:02:06,280
+المدارس كانوا بيقولوا أن الجلد هو خط دفاع الأول عن
+
+23
+00:02:06,280 --> 00:02:13,300
+الجسم يبقى هو من وضعه هو ال protection كمان
+
+24
+00:02:13,300 --> 00:02:15,640
+regulation of temperature
+
+25
+00:02:19,240 --> 00:02:23,000
+execration بيفرز العرق احنا لما بيطلع العرق على
+
+26
+00:02:23,000 --> 00:02:28,700
+الجسم بيطلع على عن طريق ال skin و synthesis of
+
+27
+00:02:28,700 --> 00:02:32,280
+vitamin D بنعرف انه احنا لما نتعرض على الشمس للشمس
+
+28
+00:02:32,280 --> 00:02:40,360
+بيصير في عندنا افرازلهرمون او لفيتامين D المهم
+
+29
+00:02:40,360 --> 00:02:45,680
+كتير في عملية انتصاص الكالسوم والبوتاسيوم وكمان ال
+
+30
+00:02:45,680 --> 00:02:49,800
+immune system هو ال first defense barrier of the
+
+31
+00:02:49,800 --> 00:02:55,440
+immune system يبقى نرجع نقول ان ال skin بيقدملي
+
+32
+00:02:55,440 --> 00:02:59,930
+اكتر من functionمنها temperature regulation منها
+
+33
+00:02:59,930 --> 00:03:06,850
+protection بمنع كمان ال .. بيحافظ على الجلد و على
+
+34
+00:03:06,850 --> 00:03:12,430
+الرطوبة بمنع السوائل أنها تطلع و نفس الوقت بيعطوني
+
+35
+00:03:12,430 --> 00:03:16,650
+إحساس و هذا كتير مهم لل sensory أنا بالنسبة لي إذا
+
+36
+00:03:16,650 --> 00:03:20,890
+حطت إيدي هنا بقدر أحس إذا كان هذا السطح بارد أو
+
+37
+00:03:20,890 --> 00:03:25,450
+سخن إذا كان شكت في إبرة أو في دبوس بحس إنه الإحساس
+
+38
+00:03:25,450 --> 00:03:30,990
+المنتشر علىكل الجلد هذا بيخليني .. بيعملي alerts،
+
+39
+00:03:30,990 --> 00:03:34,050
+بينبهني، دير بالك أنت اتلعتي على بيئة سخنة طلعت
+
+40
+00:03:34,050 --> 00:03:37,390
+على بيئة باردة، كل هذا عن طريق الإحساس، دعست على
+
+41
+00:03:37,390 --> 00:03:42,310
+مصمار، مسكت قبضت بشري مقبض سوحان، هذا كله من
+
+42
+00:03:42,310 --> 00:03:43,590
+الاسكن
+
+43
+00:03:45,370 --> 00:03:49,590
+يبقى في ال protection، إيش بدنا نقول في الموضوع ال
+
+44
+00:03:49,590 --> 00:03:53,670
+skin protection؟ عبارة عن physical barrier from
+
+45
+00:03:53,670 --> 00:04:01,130
+microorganism، بيمنع دخول أي إشي على داخل الجسم،
+
+46
+00:04:01,130 --> 00:04:06,720
+حاجزإذا كان إحنا أتعرضنا لمواد كيموية، إذا كان
+
+47
+00:04:06,720 --> 00:04:11,200
+استخدمنا ميّه نار، إيجي على إيدنا أي إشي ساق، أي
+
+48
+00:04:11,200 --> 00:04:16,620
+إشي chemical ممكن يعمل ليه؟ يدخل للجسم، فال skin
+
+49
+00:04:16,620 --> 00:04:19,540
+هذا بيوقف لعنده و بيوقفه
+
+50
+00:04:22,120 --> 00:04:27,200
+يعني إحنا لما بنخبط و أحنا مارقين أو أحنا ماشيين
+
+51
+00:04:27,200 --> 00:04:31,780
+في حفة الطاولة أو في حفة الكرسي ال skin هاد عامل
+
+52
+00:04:31,780 --> 00:04:35,040
+زي المخدة كده على الأشياء على طريق السبكوتانيا
+
+53
+00:04:35,040 --> 00:04:38,880
+الستشفر اللي موجودة فبيمنع ال mechanical trauma
+
+54
+00:04:38,880 --> 00:04:41,720
+prevent dehydration بيمنع السوائل و excessive
+
+55
+00:04:41,720 --> 00:04:45,920
+secretions بيمنعها أنها تطلع فبيمنع الجفاف protect
+
+56
+00:04:46,650 --> 00:04:50,690
+بها millennium excessive ultraviolet exposure طبعا
+
+57
+00:04:50,690 --> 00:04:53,790
+إحنا اللي ببقى متعرض لأشعة الشمس نبقى ماشيين جلدنا
+
+58
+00:04:53,790 --> 00:04:57,910
+كله إحنا من حب ربنا يعني إحنا النساء المسلمات بكون
+
+59
+00:04:57,910 --> 00:05:02,190
+جسمهم بطة مع عدى الوجه هو الكفان السنة كانت منأو
+
+60
+00:05:02,190 --> 00:05:07,570
+الحكمة من كشف الوجه والكفان هو أن أكتر مناطق هذه
+
+61
+00:05:07,570 --> 00:05:10,450
+ممكن أنها تعمل synthesis تعرضها للشمس يعمل
+
+62
+00:05:10,450 --> 00:05:16,230
+synthesis للافيتامين دي هي الإيدين والوجه لكن
+
+63
+00:05:16,230 --> 00:05:20,650
+الجسم إذا اتعرض ل excessive sun light ممكن يتعرض
+
+64
+00:05:20,650 --> 00:05:28,330
+لburn لكن الجلد هو اللي بيحمي الجسم من ال sun burn
+
+65
+00:05:28,330 --> 00:05:33,150
+أما ال functionالتانية فهي ال sensation ال
+
+66
+00:05:33,150 --> 00:05:37,730
+sensation اللي انت شعر الواسع ل ال sensory organs
+
+67
+00:05:37,730 --> 00:05:47,650
+أو ل ال tactile tissue اللي بتخلينا نحس بكل إشي
+
+68
+00:05:47,650 --> 00:05:52,110
+ممكن إحنا نتعرض عليهنتعرض له somatic sensory
+
+69
+00:05:52,110 --> 00:05:57,490
+receptors detect stimuli that permit use detect ال
+
+70
+00:05:57,490 --> 00:06:01,970
+pressure ال touch ال temperature ال pain all the
+
+71
+00:06:01,970 --> 00:06:05,550
+general sensations يعني احنا لو مسيكنا و احنا
+
+72
+00:06:05,550 --> 00:06:10,470
+مغمضين بيدنا خمس شكل بنحس مسيكنا قلم بنعرف انه هذا
+
+73
+00:06:10,470 --> 00:06:13,470
+قلم مسيكنا الجوال هذا جوالي ولا مش جوالي حتى و انا
+
+74
+00:06:13,470 --> 00:06:17,430
+مش شايفه اه بعرف لاني عارف احزم جوالي و شكله كل
+
+75
+00:06:17,430 --> 00:06:22,190
+الاحساس بيصير عن طريقلـ skin لو وقع على رجل ناشي
+
+76
+00:06:22,190 --> 00:06:25,290
+طبعا الناس اللي بتفقد الاحساس هذه بتكون عرضة اكتر
+
+77
+00:06:25,290 --> 00:06:31,190
+ل ال injury كمان
+
+78
+00:06:31,190 --> 00:06:36,110
+ال skin فيه خاصية ل flexibility وهي بيساعد على ال
+
+79
+00:06:36,110 --> 00:06:40,150
+elasticity هذه بيساعد على تغيير الشكل يعني انا بدي
+
+80
+00:06:40,150 --> 00:06:43,150
+اغنط ايدي بدي افتح ايدي لو لإن ال skin عندي
+
+81
+00:06:43,150 --> 00:06:47,110
+flexible كان انا مقدرش اغنط ايدي لو اضطربنا ان شخص
+
+82
+00:06:47,110 --> 00:06:51,400
+اخد مثلا جروحبصار عنده جروح في هذه المنطقة بيصير
+
+83
+00:06:51,400 --> 00:06:56,060
+فردة إيده هذه صعبة ليش؟ لأنه بيصير ال skin مش
+
+84
+00:06:56,060 --> 00:06:59,300
+flexible فمعناه أني أنا الحركات اللي بعملها هذه
+
+85
+00:06:59,300 --> 00:07:02,440
+كلها اللي بيسمحلي فيها اللي بيعطيني ال range فيها
+
+86
+00:07:02,440 --> 00:07:07,820
+صحيح المدى العضلي لكن كمان ال skin flexibility of
+
+87
+00:07:07,820 --> 00:07:11,060
+the skin و ال execrations اللي هي ال water و ال
+
+88
+00:07:11,060 --> 00:07:14,340
+urea و كل الأشياء السموم اللي بتطلع عن طريق ال
+
+89
+00:07:14,340 --> 00:07:18,980
+sweetالهادية بتخلص منها الجسم اتكلم ال sweating
+
+90
+00:07:18,980 --> 00:07:24,460
+glands هي تقريبا مكيف الجسم اللي بيخلي الجسم يتعرق
+
+91
+00:07:24,460 --> 00:07:29,700
+فبيقلل من حرارة الداخلية للجسم ال immune ليش؟ لإن
+
+92
+00:07:29,700 --> 00:07:33,720
+في عنا حاجة اسمها longer handsسلز هذه طبيعتها
+
+93
+00:07:33,720 --> 00:07:38,900
+بتساعد في الimmune system فهي فيها الفاغوسيتوس أو
+
+94
+00:07:38,900 --> 00:07:43,480
+الفاغوسيتك سلز بتعمل destroying البكتيريا نلاحظ ان
+
+95
+00:07:43,480 --> 00:07:47,040
+احنا اول ما بنجريها او هدا بتبدأ عندنا الحمراء و
+
+96
+00:07:47,040 --> 00:07:52,500
+بتبدأ تصير في عملية هجوم من ال white blood cells
+
+97
+00:07:52,500 --> 00:07:57,840
+في المكان حتى انها تمنع دخول البكتيريا وتخلص منها
+
+98
+00:08:00,240 --> 00:08:05,300
+طبعا الـ heat loss تقريبا احنا 80% of heat loss
+
+99
+00:08:05,300 --> 00:08:08,960
+occurs through the skin لأن الجسم إذا كان في جو
+
+100
+00:08:08,960 --> 00:08:12,960
+حار زي هيك دلو محتفظ بالحرارة محتفظ بالحرارة بعد
+
+101
+00:08:12,960 --> 00:08:17,920
+هيك إيش بيصير؟ خلينا نقول بالعربي بتنطق ال organs
+
+102
+00:08:17,920 --> 00:08:20,780
+يعني مش معقول إنهم دلوا ارتفاع مستمر في درجات
+
+103
+00:08:20,780 --> 00:08:25,340
+الحرارة فالجسم بيخلص ال .. ال gel بيخلص الجسم من
+
+104
+00:08:25,340 --> 00:08:30,470
+الحرارة عن طريق ال sweatingبضمن 20% occurred
+
+105
+00:08:30,470 --> 00:08:33,830
+through the mucous والرسبيراتوري والديجستف
+
+106
+00:08:33,830 --> 00:08:38,310
+والريونارياتريكس أما ال skin بياخد 80% من تخلص
+
+107
+00:08:38,310 --> 00:08:44,110
+الجسم من الحرارة الزائدةروح لا إشي مهم كتير في
+
+108
+00:08:44,110 --> 00:08:47,970
+عندنا three layers of skin هذا ال skin اللي إحنا
+
+109
+00:08:47,970 --> 00:08:52,550
+شايفينه اللي بنمسكه سواء كان رقيق أو كان أكميل فهو
+
+110
+00:08:52,550 --> 00:08:56,430
+بتكون من تلاتة layers اتنين منهم هي layers of skin
+
+111
+00:08:56,430 --> 00:08:59,570
+و ال layer بتاع اللي هو subcutaneous layer هو
+
+112
+00:08:59,570 --> 00:09:03,770
+أحيانا ما بيعتبر هو دائما بيعتبر part of the skin
+
+113
+00:09:03,770 --> 00:09:06,850
+يبقى في عندنا ال epidermis في عندنا ال dermis في
+
+114
+00:09:06,850 --> 00:09:11,290
+عندنا subcutaneous layersالsubcutaneous اللي هو
+
+115
+00:09:11,290 --> 00:09:16,470
+sub كلمة sub دايما تعني تحت تحت الجلد طبقة من
+
+116
+00:09:16,470 --> 00:09:20,450
+الدهون بتكون تحت الجلد يبقى beneath the dermis not
+
+117
+00:09:20,450 --> 00:09:26,930
+part of the skin زي ما احنا شايفين هذا الشكل هنوضح
+
+118
+00:09:26,930 --> 00:09:31,030
+اكتر ونتعرف على ال epidermis كلمة epidermis means
+
+119
+00:09:31,030 --> 00:09:36,670
+فوقفوق above اللي بيه الطبقة الخارجية طبعا الطبقة
+
+120
+00:09:36,670 --> 00:09:40,830
+الخارجية بتكون فيش فيها blood vessels keratinized
+
+121
+00:09:40,830 --> 00:09:45,530
+فيها ال protein ال keratin thickenest on the palm
+
+122
+00:09:45,530 --> 00:09:48,670
+and the sole قلنا في عندنا نوعين من ال skin في
+
+123
+00:09:48,670 --> 00:09:51,530
+عندنا thick skin و في عندنا thin skin ال thick
+
+124
+00:09:51,530 --> 00:09:57,390
+skin بيكون في palm of the foot and the sole of the
+
+125
+00:09:57,390 --> 00:10:04,390
+palm of the hand and the sole of the footالـ
+
+126
+00:10:04,390 --> 00:10:08,090
+melanocytes provide melanin الـ melanin هو الصبغة
+
+127
+00:10:08,090 --> 00:10:13,570
+اللي بتحقق يعني بيكون على أثرها تركيزها نوع لون ال
+
+128
+00:10:13,570 --> 00:10:17,750
+skin إذا كان هذا بشرته بيضا، هذا بشرته صمرة، هذا
+
+129
+00:10:17,750 --> 00:10:21,890
+بشرته أمحي، هذا بشرته سوداء يكون تركيز ال melanin
+
+130
+00:10:21,890 --> 00:10:26,610
+فيها أكتر طبعا في حاجة اسمها Basel أو Basement
+
+131
+00:10:26,610 --> 00:10:30,610
+Membrane اتكلمنا على ال epithelial cells في المرات
+
+132
+00:10:30,610 --> 00:10:34,780
+السابقة ال epithelial cells قلنا تبقىالاخيرة أو
+
+133
+00:10:34,780 --> 00:10:38,080
+التحتانية هي عبارة عن Basel سل أو بنسميها
+
+134
+00:10:38,080 --> 00:10:44,480
+Basements ونوع ال ابيتاليا السل اللي موجودة
+
+135
+00:10:44,480 --> 00:10:52,460
+stratified squamous لأنها هي شكلها كده مسطح طبعا
+
+136
+00:10:52,460 --> 00:10:58,180
+في عندناأنواع الـ cells اللي بتكون ال epidermis في
+
+137
+00:10:58,180 --> 00:11:02,140
+عينها الكيراتونسايت والملانوسايت والـ Langerhans
+
+138
+00:11:02,140 --> 00:11:08,880
+كل واحدة منهم لها وظيفة الكيراتونسايت عبارة عن 90%
+
+139
+00:11:08,880 --> 00:11:12,760
+من هذه ال cells اللي موجودة ال principle structure
+
+140
+00:11:12,760 --> 00:11:17,860
+element for outer skin بتكون الطبقة الخارجية من ال
+
+141
+00:11:17,860 --> 00:11:21,660
+skin أما الملانوسايتهي الـ Pigmentation اللي بتعمل
+
+142
+00:11:21,660 --> 00:11:27,260
+لون الجلد products producing 5% of the total
+
+143
+00:11:27,260 --> 00:11:31,840
+contribute and scale color filter ال ultraviolet
+
+144
+00:11:31,840 --> 00:11:37,100
+light هي اللي بتساعد على الحفاظ على الجلد من ال
+
+145
+00:11:37,100 --> 00:11:41,720
+ultraviolet اللي بتجينا من الشمسlarger hands هي
+
+146
+00:11:41,720 --> 00:11:45,180
+الـdendritic branches عبارة عن antigen
+
+147
+00:11:45,180 --> 00:11:51,700
+-representing cell ال ABCs they play the role in
+
+148
+00:11:51,700 --> 00:11:56,380
+immune response إذا تعرض الجسم أو الجلد لأي insult
+
+149
+00:11:56,380 --> 00:12:02,700
+يعني insect مثلا بعت إجتنا نحلة إجتنا أي insect
+
+150
+00:12:02,700 --> 00:12:07,970
+إجت وقرستنا فعلى طول بتشتغل longer handsوبتعمل ليه
+
+151
+00:12:07,970 --> 00:12:13,550
+بتزود المناعة في هذا المكان أما ال epidermis كمان
+
+152
+00:12:13,550 --> 00:12:17,190
+بتكون من layers يعني هي طبقة رقيقة صحيح لكن بتكون
+
+153
+00:12:17,190 --> 00:12:21,430
+من layers في حالة ال thick skin بتكون خمسة layers
+
+154
+00:12:21,430 --> 00:12:25,670
+في حالة ال thin skin بتكون أربعة layers ال layers
+
+155
+00:12:25,670 --> 00:12:32,750
+هذه عبارة عن لو أخدناها من السطح للأسفل فعنا ال
+
+156
+00:12:32,750 --> 00:12:38,220
+striatum corneumوالسترياتم لوسيديا والسترياتم
+
+157
+00:12:38,220 --> 00:12:43,200
+اللانيروزام والاسفاينس والبيزل ناخدهم واحدة واحدة
+
+158
+00:12:43,200 --> 00:12:54,440
+ونتعرف عليهم الآن البيزل
+
+159
+00:12:54,440 --> 00:12:59,430
+استرياتمالطبقة القاعدية إحنا بنسميها عبارة عن
+
+160
+00:12:59,430 --> 00:13:02,970
+single layer columnar إيش يعني columnar يعني شكل
+
+161
+00:13:02,970 --> 00:13:07,950
+ال cells بهذا الشكل هي طبقة واحدة لكن ال cells
+
+162
+00:13:07,950 --> 00:13:13,790
+columnar تمام؟
+
+163
+00:13:17,090 --> 00:13:20,870
+زي ما اتعرفنا في محاضرتنا تبع الـ Epithelium
+
+164
+00:13:20,870 --> 00:13:27,490
+Columnar cells under cosmetosis و migration بتتقسم
+
+165
+00:13:27,490 --> 00:13:35,650
+و بتروح بتهاجر حتى تصل للسطح و تموت أما الشوكية لـ
+
+166
+00:13:35,650 --> 00:13:42,360
+striatum spinosum اللي هي Spiny layer calledSales
+
+167
+00:13:42,360 --> 00:13:46,560
+arranged in eight to ten يعني هنا الأول ال layer
+
+168
+00:13:46,560 --> 00:13:50,240
+الأولاني أو ال base بتكون من layer واحد أما ال
+
+169
+00:13:50,240 --> 00:13:55,800
+layer التاني بتكون من eight to ten layers
+
+170
+00:13:58,910 --> 00:14:03,590
+شكلها بيكون عامل زي ال spine يعني بيكون مبوظ كده
+
+171
+00:14:03,590 --> 00:14:09,770
+spinous تمام into spiny shape cell rich in RNA
+
+172
+00:14:09,770 --> 00:14:16,190
+فيها ال RNA أما ال granulosome أو ال striatum
+
+173
+00:14:18,430 --> 00:14:22,890
+Cells arranged two to four layers filled with
+
+174
+00:14:22,890 --> 00:14:27,930
+keratin هي ليه؟ Granules contains high level of
+
+175
+00:14:27,930 --> 00:14:35,910
+lysomal enzymes ليزومال؟ Enzyme أما لسريات
+
+176
+00:14:35,910 --> 00:14:39,590
+الملوسيديا فهي clear layer cell filled with
+
+177
+00:14:39,590 --> 00:14:45,240
+keratin precursor called elidinabsent in the thin
+
+178
+00:14:45,240 --> 00:14:51,080
+skin فهذه الطبقة الو سيديام مش موجودة في ال skin
+
+179
+00:14:51,080 --> 00:14:57,300
+thin أما ال sternum corium اللي هي horny layers
+
+180
+00:14:57,300 --> 00:15:01,780
+مُس superficial layer dead cells filled with
+
+181
+00:15:01,780 --> 00:15:09,980
+keratin ايرياها دي الطبقة الخارجية لل skin
+
+182
+00:15:16,070 --> 00:15:19,070
+طبعا في حاجة اسمها dermal and epidermal function
+
+183
+00:15:19,070 --> 00:15:24,250
+بين الديرم وبين الepiderm في انه junction بنوصل
+
+184
+00:15:24,250 --> 00:15:30,170
+البعض عبارة عن placement membrane specialized
+
+185
+00:15:30,170 --> 00:15:35,370
+fibers element and polysaccharide gel served as
+
+186
+00:15:35,370 --> 00:15:42,990
+glue glue اش يعني يعني زي صمغية glue صمغ glue
+
+187
+00:15:43,290 --> 00:15:46,730
+the epidermis to the dermis below junctions of
+
+188
+00:15:46,730 --> 00:15:51,730
+partial barrier to passage of some cells and large
+
+189
+00:15:51,730 --> 00:15:54,870
+molecules يعني عبارة عن حاجز هنا الحاجز بين
+
+190
+00:15:54,870 --> 00:16:00,050
+الديرمس وبين ال epidermis نروح للديرمس sometimes
+
+191
+00:16:00,050 --> 00:16:04,670
+called true skin الحقيقة اللي الأدمة بيسموها هناك
+
+192
+00:16:04,670 --> 00:16:08,310
+البشرة ال epidermis البشرة أما هذه بيسموها الأدمة
+
+193
+00:16:09,230 --> 00:16:12,910
+much thicker than epidermis and lies beneath it
+
+194
+00:16:12,910 --> 00:16:16,970
+أخمل شوية من epidermis بتكون هو عبارة من collagen
+
+195
+00:16:16,970 --> 00:16:21,570
+fibers and elastin fibers هنشوفه شوية gives
+
+196
+00:16:21,570 --> 00:16:26,430
+strength to skin بأول ال skin serve as re-servers
+
+197
+00:16:26,430 --> 00:16:30,730
+area for storage of water and electrolyte بعبارة
+
+198
+00:16:30,730 --> 00:16:36,270
+عن هو storage للميه و ال electrolytes epidermis
+
+199
+00:16:37,360 --> 00:16:41,880
+تقريبا ال thickness تبقى من واحد لاثنين ميلي في
+
+200
+00:16:41,880 --> 00:16:48,900
+ديرمال papilla هليمات ال danceDense Epidermis to
+
+201
+00:16:48,900 --> 00:16:53,380
+the underlying tissue هو عبارة عن الوصلة ما بين ال
+
+202
+00:16:53,380 --> 00:16:57,260
+Epidermis و بين ال underlying tissue بتكون من ال
+
+203
+00:16:57,260 --> 00:17:01,540
+regular dense connective tissue في muscle cells في
+
+204
+00:17:01,540 --> 00:17:05,120
+nerve cells specialised sensory receptors في blood
+
+205
+00:17:05,120 --> 00:17:09,820
+vessels في hair follicles و egg glands طبعا الصورة
+
+206
+00:17:09,820 --> 00:17:16,260
+هنا بتوضحتقريبا ال dermis ال epidermis و ال dermis
+
+207
+00:17:16,260 --> 00:17:20,580
+subcutaneous تشوف مضايق أنه ال dermis بيحتوي على
+
+208
+00:17:20,580 --> 00:17:25,320
+إذا طلعنا هنا بنشوف ال papillae اللي هي عاملة زي
+
+209
+00:17:25,320 --> 00:17:30,320
+التعرش بهذا الشكل عشان تصير داخل ال dermis مع ال
+
+210
+00:17:30,320 --> 00:17:32,340
+epidermis
+
+211
+00:17:34,770 --> 00:17:40,590
+و في عندنا كل الـ Receptors هاي الموجودة و في
+
+212
+00:17:40,590 --> 00:17:43,910
+عندنا الـ glands زي الـ sweating gland في عندنا ال
+
+213
+00:17:43,910 --> 00:17:47,830
+hair follicles ال sweating gland هي عاملة زي تيوب
+
+214
+00:17:47,830 --> 00:17:54,050
+اللي بتطلع ال sweating على سطح الجلد فيها هنا ال
+
+215
+00:17:54,050 --> 00:17:57,590
+subcutaneous tissue ما تحت ال dermis
+
+216
+00:18:05,160 --> 00:18:07,900
+Condamnus contains various structures فيه ال
+
+217
+00:18:07,900 --> 00:18:11,600
+erecto-pili muscle and hair follicles، إذا بلاحظ
+
+218
+00:18:11,600 --> 00:18:15,980
+أن الشخص لو خاف أو برد بتلاقي الشعر للجسم، احنا
+
+219
+00:18:15,980 --> 00:18:22,620
+عارفين أن كل الجسم بيتغطى بشعرإلا بعد المناطق في
+
+220
+00:18:22,620 --> 00:18:26,540
+موجود الجسم، هلقيتها؟ لو شخص خافة بحس إنه شعر
+
+221
+00:18:26,540 --> 00:18:30,860
+الجسم و كأنه بيوقف، بحيث بنقول أب شعر بدني كده،
+
+222
+00:18:30,860 --> 00:18:34,760
+بنقول أشعرتي، إيش يعني؟ هذي ال .. ال rector بال
+
+223
+00:18:34,760 --> 00:18:38,260
+lie muscles هي اللي بتعمل contraction فبيوقف،
+
+224
+00:18:38,260 --> 00:18:42,620
+contraction فبيوقف شعر الجسمSensory receptors
+
+225
+00:18:42,620 --> 00:18:46,640
+موجود فيها sweating and sebaceous gland اللي موجود
+
+226
+00:18:46,640 --> 00:18:54,170
+فيها ال gland الدهنيةالـBlood vessels ريتش فاسكولر
+
+227
+00:18:54,170 --> 00:18:56,790
+supply plays a critical role in temperature
+
+228
+00:18:56,790 --> 00:19:00,470
+regulation طيب و احنا قولنا كل ما كان فيه blood
+
+229
+00:19:00,470 --> 00:19:04,330
+supply أكتر كل ما الجسم الجلد كان أسخن طب عن ال
+
+230
+00:19:04,330 --> 00:19:07,190
+layers احنا بنبنع عن two layers ال papillary layer
+
+231
+00:19:07,190 --> 00:19:12,230
+و ال reticular layer ال papillary layer compose of
+
+232
+00:19:12,230 --> 00:19:15,790
+dermal papillae that protect into epidermis
+
+233
+00:19:17,070 --> 00:19:21,450
+contains collagen and elastin الcollagen بيعطي
+
+234
+00:19:21,450 --> 00:19:25,930
+strength و ال elastin بيعطي مرونة ال collagen
+
+235
+00:19:25,930 --> 00:19:31,770
+لإنها fibers و fibers قوية فهي بتعطي ال strength
+
+236
+00:19:31,770 --> 00:19:36,130
+لل skin بتقوي أما ال elastic fibers بتعطيني
+
+237
+00:19:36,130 --> 00:19:39,970
+المرونة عشان أنا أقدر أغمض و أفتح و أمد إيدي و
+
+238
+00:19:39,970 --> 00:19:44,150
+أرفعها أوطي و أقوم كل الحركات اللي إحنا بنعملها
+
+239
+00:19:44,370 --> 00:19:49,750
+contains the dermal-epidermic junction for ionic
+
+240
+00:19:49,750 --> 00:19:53,110
+pattern that gives individual fingertips، عارفين
+
+241
+00:19:53,110 --> 00:19:56,090
+ال fingers؟ احنا كل واحد فيه بصمة، فينا على
+
+242
+00:19:56,090 --> 00:20:03,810
+الأصابع كل جسم له بصمةالـ reticular layer عبارة عن
+
+243
+00:20:03,810 --> 00:20:08,910
+disc interlaced يعني هي عبارة عن fibers،
+
+244
+00:20:08,910 --> 00:20:14,070
+collagenous fibers لكن هي متشابكة و سميكة and
+
+245
+00:20:14,070 --> 00:20:17,970
+elastic fibers to make the skin tough and
+
+246
+00:20:17,970 --> 00:20:24,190
+stretchable يعني بتخلينا تكون ال skin في إمكانية
+
+247
+00:20:24,190 --> 00:20:28,810
+لإنه ينمغط، عشان ينمغط أن يكون فيه نوع من المرونة
+
+248
+00:20:29,780 --> 00:20:35,600
+في النحج اسمها lines of cleavage lines of cleavage
+
+249
+00:20:35,600 --> 00:20:42,380
+عبارة عن خطوط موجودة في ال skin بتحدد ال skin
+
+250
+00:20:42,380 --> 00:20:45,860
+identifying the predominant orientation of
+
+251
+00:20:45,860 --> 00:20:50,000
+collagen fibers clinically and surgically
+
+252
+00:20:50,000 --> 00:20:53,240
+significant because cut can result in a slow
+
+253
+00:20:53,240 --> 00:20:58,340
+healingand increase scarring تطلع على الصورة اللي
+
+254
+00:20:58,340 --> 00:21:04,520
+قدامنا بنلاقي انه ال cleavage lines موجودة طولية
+
+255
+00:21:04,520 --> 00:21:12,160
+هنا في ال upper and lower limb وموجودة عرضية في ال
+
+256
+00:21:12,160 --> 00:21:20,080
+trunk طيب هاي أشفيدتها لو صار cut في اتجاه
+
+257
+00:21:21,690 --> 00:21:26,790
+الـ vipers بيكون سهل الالتئام لكن لو أصار cuts
+
+258
+00:21:26,790 --> 00:21:31,850
+perpendicular فالمون
+
+259
+00:21:31,850 --> 00:21:37,110
+بيصير صعب الالتئام بيصير scarring بيصير scar فهذه
+
+260
+00:21:37,110 --> 00:21:43,120
+مهمة كتير لل surgeon أنه يعرف اتجاههالـ lines هذه
+
+261
+00:21:43,120 --> 00:21:47,860
+حتى يساعدوا في اتخاذ القرار في أي اتجاه هو يفتح
+
+262
+00:21:47,860 --> 00:21:51,960
+طولي ولا عردي طبعا كل ما كان في اتجاه ال collagen
+
+263
+00:21:51,960 --> 00:21:59,570
+fibers كل ما كان ال healing أسرع و أفضلالـ dermis
+
+264
+00:21:59,570 --> 00:22:06,270
+remains a scar و ال dermal growth and repair ال
+
+265
+00:22:06,270 --> 00:22:11,690
+dermis regenerates itself as does epidermis يعني
+
+266
+00:22:11,690 --> 00:22:16,350
+بيصير regeneration للepidermis
+
+267
+00:22:16,350 --> 00:22:22,010
+في عندنا ال subcutaneous layer ال subcutaneous
+
+268
+00:22:22,010 --> 00:22:29,380
+layer عبارة عن طبقةالـ Dermis بتعملي زي فاشية
+
+269
+00:22:29,380 --> 00:22:35,820
+نسميها Hypodermis عبارة عن موز connective tissue،
+
+270
+00:22:35,820 --> 00:22:40,920
+adipose، insulates، and measure blood vessels بتمر
+
+271
+00:22:40,920 --> 00:22:46,980
+فيها، فيها خلايا دهنية وكمان بتعملي عملية عزل وفصل
+
+272
+00:22:46,980 --> 00:22:52,180
+ما بين ال subcutaneous بين ال dermis و ال layers
+
+273
+00:22:52,180 --> 00:22:53,340
+اللي تحتها
+
+274
+00:22:56,680 --> 00:22:59,480
+الـ hypodermis also called subcutaneous layer or
+
+275
+00:22:59,480 --> 00:23:03,100
+superficial fascia لأنه في عندنا deep fascia ال
+
+276
+00:23:03,100 --> 00:23:06,720
+superficial fascia اللي بتكون تحت ال skin على طول
+
+277
+00:23:06,720 --> 00:23:12,400
+هي عبارة عن صموت كاملة لبسها الجسم من الجمجمة لحد
+
+278
+00:23:12,400 --> 00:23:18,460
+اللوارق limbs forming عندنا deep to the dermis تحت
+
+279
+00:23:18,460 --> 00:23:22,200
+ال dermis forming connection between the skin and
+
+280
+00:23:22,200 --> 00:23:27,210
+other structure هي it's not part of the skinطبعا
+
+281
+00:23:27,210 --> 00:23:31,950
+احنا الصورة هذه بتوضح طبقات
+
+282
+00:23:31,950 --> 00:23:37,490
+ال epidermis جميعها
+
+283
+00:23:37,490 --> 00:23:43,450
+و كمان بتوضحلي ال dermis ال بالعيز كمان و ال
+
+284
+00:23:43,450 --> 00:23:52,450
+subcutaneous هتكون تحت هنابنشوف مكوناتها فى عندنا
+
+285
+00:23:52,450 --> 00:23:57,050
+dead keratinocytes فى عندنا 3-ethamcorneum هنا
+
+286
+00:23:57,050 --> 00:24:04,610
+شايفينها عندنا الوسيدياعنا ال granulosome وعنا ال
+
+287
+00:24:04,610 --> 00:24:10,050
+spinous أو ال spinosome وعنا ال basal ليها هذه
+
+288
+00:24:10,050 --> 00:24:14,450
+الطبقة اللي قلنا هي عبارة عن طبقة من ال ال
+
+289
+00:24:14,450 --> 00:24:21,030
+columnar cells روح ال dermis الطبقة اللي تحتها هذه
+
+290
+00:24:21,030 --> 00:24:24,870
+المكونات طبعتها
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..781fccc1f62f6a82e872b07374bd7483d8504081
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk_raw.json
@@ -0,0 +1 @@
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"Cells arranged two to four layers filled with keratin هي ليه؟ Granules contains high level of lysomal enzymes ليزومال؟ Enzyme أما لسريات الملوسيديا فهي clear layer cell filled with keratin precursor called elidin", "tokens": [34, 13677, 18721, 732, 281, 1451, 7914, 6412, 365, 19377, 22685, 39896, 32239, 3224, 22807, 23554, 3473, 8306, 1090, 1496, 295, 48670, 298, 304, 29299, 5296, 1829, 11622, 20498, 6027, 22807, 2193, 1229, 1398, 5551, 15042, 5296, 3794, 16572, 9307, 9673, 1211, 41779, 25708, 25528, 6156, 3224, 1829, 1850, 4583, 2815, 6412, 365, 19377, 22685, 41736, 284, 1219, 806, 327, 259], "avg_logprob": -0.4886592597730698, "compression_ratio": 1.3626373626373627, "no_speech_prob": 0.0, "words": [{"start": 858.43, "end": 859.13, "word": "Cells", "probability": 0.48297119140625}, {"start": 859.13, "end": 859.97, "word": " arranged", "probability": 0.498291015625}, {"start": 859.97, "end": 860.45, "word": " two", "probability": 0.564453125}, {"start": 860.45, "end": 860.81, "word": 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specialised", "probability": 0.3504638671875}, {"start": 1023.38, "end": 1023.8, "word": " sensory", "probability": 0.85546875}, {"start": 1023.8, "end": 1024.58, "word": " receptors", "probability": 0.82568359375}, {"start": 1024.58, "end": 1024.84, "word": " في", "probability": 0.87646484375}, {"start": 1024.84, "end": 1025.12, "word": " blood", "probability": 0.9697265625}, {"start": 1025.12, "end": 1025.64, "word": " vessels", "probability": 0.84228515625}, {"start": 1025.64, "end": 1025.86, "word": " في", "probability": 0.94482421875}, {"start": 1025.86, "end": 1026.1, "word": " hair", "probability": 0.94775390625}, {"start": 1026.1, "end": 1026.9, "word": " follicles", "probability": 0.960205078125}, {"start": 1026.9, "end": 1027.4, "word": " و", "probability": 0.32177734375}, {"start": 1027.4, "end": 1028.16, "word": " egg", "probability": 0.375732421875}, {"start": 1028.16, "end": 1028.58, "word": " glands", "probability": 0.546875}, {"start": 1028.58, "end": 1029.38, "word": " 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"probability": 0.76318359375}, {"start": 1048.68, "end": 1049.22, "word": " dermis", "probability": 0.99267578125}, {"start": 1049.22, "end": 1049.52, "word": " مع", "probability": 0.9892578125}, {"start": 1049.52, "end": 1050.32, "word": " ال", "probability": 0.94189453125}, {"start": 1050.32, "end": 1052.34, "word": " epidermis", "probability": 0.9903971354166666}], "temperature": 1.0}, {"id": 46, "seek": 107758, "start": 1054.77, "end": 1077.59, "text": "و في عندنا كل الـ Receptors هاي الموجودة و في عندنا الـ glands زي الـ sweating gland في عندنا ال hair follicles ال sweating gland هي عاملة زي تيوب اللي بتطلع ال sweating على سطح الجلد فيها هنا ال subcutaneous tissue ما تحت ال dermis", "tokens": [2407, 8978, 43242, 8315, 28242, 2423, 39184, 1300, 1336, 830, 8032, 47302, 9673, 29245, 23328, 3660, 4032, 8978, 43242, 8315, 2423, 39184, 49533, 30767, 1829, 2423, 39184, 25438, 43284, 8978, 43242, 8315, 2423, 2578, 25483, 5350, 2423, 25438, 43284, 39896, 6225, 10943, 37977, 30767, 1829, 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لبسها الجسم من الجمجمة لحد اللوارق limbs forming عندنا deep to the dermis تحت ال dermis forming connection between the skin and other structure هي it's not part of the skin", "tokens": [6027, 39184, 7420, 378, 966, 271, 611, 1219, 1422, 6672, 15447, 4583, 420, 34622, 30632, 2755, 5296, 33456, 3224, 8978, 43242, 8315, 2452, 30632, 2755, 2423, 34622, 30632, 2755, 13672, 1829, 39894, 30544, 6055, 33753, 2423, 3178, 15844, 23032, 12610, 39896, 6225, 3555, 9640, 3660, 18871, 20328, 2304, 35473, 9122, 10943, 37977, 5296, 3555, 3794, 11296, 25724, 38251, 9154, 25724, 2304, 7435, 46007, 5296, 24401, 13672, 2407, 9640, 4587, 29315, 15745, 43242, 8315, 2452, 281, 264, 33080, 271, 6055, 33753, 2423, 33080, 271, 15745, 4984, 1296, 264, 3178, 293, 661, 3877, 39896, 309, 311, 406, 644, 295, 264, 3178], "avg_logprob": -0.22906249791383743, "compression_ratio": 1.6367041198501873, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 1376.68, "end": 1376.94, "word": "الـ", "probability": 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"probability": 0.783203125}, {"start": 1387.24, "end": 1387.52, "word": " عبارة", "probability": 0.9334716796875}, {"start": 1387.52, "end": 1387.76, "word": " عن", "probability": 0.99755859375}, {"start": 1387.76, "end": 1388.2, "word": " صموت", "probability": 0.6421712239583334}, {"start": 1388.2, "end": 1389.02, "word": " كاملة", "probability": 0.9306640625}, {"start": 1389.02, "end": 1389.6, "word": " لبسها", "probability": 0.944580078125}, {"start": 1389.6, "end": 1390.1, "word": " الجسم", "probability": 0.941162109375}, {"start": 1390.1, "end": 1390.66, "word": " من", "probability": 0.98681640625}, {"start": 1390.66, "end": 1391.56, "word": " الجمجمة", "probability": 0.871826171875}, {"start": 1391.56, "end": 1392.4, "word": " لحد", "probability": 0.939453125}, {"start": 1392.4, "end": 1393.7, "word": " اللوارق", "probability": 0.564208984375}, {"start": 1393.7, "end": 1394.66, "word": " limbs", "probability": 0.120849609375}, {"start": 1394.66, "end": 1395.92, "word": " forming", "probability": 0.7861328125}, {"start": 1395.92, "end": 1396.92, "word": " عندنا", "probability": 0.787841796875}, {"start": 1396.92, "end": 1397.02, "word": " deep", "probability": 0.88330078125}, {"start": 1397.02, "end": 1397.48, "word": " to", "probability": 0.93896484375}, {"start": 1397.48, "end": 1397.68, "word": " the", "probability": 0.90478515625}, {"start": 1397.68, "end": 1398.12, "word": " dermis", "probability": 0.993896484375}, {"start": 1398.12, "end": 1398.46, "word": " تحت", "probability": 0.93359375}, {"start": 1398.46, "end": 1398.62, "word": " ال", "probability": 0.5732421875}, {"start": 1398.62, "end": 1399.26, "word": " dermis", "probability": 0.916259765625}, {"start": 1399.26, "end": 1399.98, "word": " forming", "probability": 0.83935546875}, {"start": 1399.98, "end": 1400.78, "word": " connection", "probability": 0.83642578125}, {"start": 1400.78, "end": 1401.38, "word": " between", "probability": 0.94580078125}, {"start": 1401.38, "end": 1401.66, "word": " the", "probability": 0.90869140625}, {"start": 1401.66, "end": 1401.96, "word": " skin", "probability": 0.9609375}, {"start": 1401.96, "end": 1402.2, "word": " and", "probability": 0.96044921875}, {"start": 1402.2, "end": 1402.46, "word": " other", "probability": 0.8173828125}, {"start": 1402.46, "end": 1403.14, "word": " structure", "probability": 0.7001953125}, {"start": 1403.14, "end": 1403.58, "word": " هي", "probability": 0.7080078125}, {"start": 1403.58, "end": 1404.12, "word": " it's", "probability": 0.73388671875}, {"start": 1404.12, "end": 1404.44, "word": " not", "probability": 0.95556640625}, {"start": 1404.44, "end": 1404.94, "word": " part", "probability": 0.91552734375}, {"start": 1404.94, "end": 1405.48, "word": " of", "probability": 0.9814453125}, {"start": 1405.48, "end": 1406.06, "word": " the", "probability": 0.927734375}, {"start": 1406.06, "end": 1406.38, "word": " skin", "probability": 0.9423828125}], "temperature": 1.0}, {"id": 61, "seek": 142811, "start": 1406.85, "end": 1428.11, "text": "طبعا احنا الصورة هذه بتوضح طبقات ال epidermis جميعها و كمان بتوضحلي ال dermis ال بالعيز كمان و ال subcutaneous هتكون تحت هنا", "tokens": [9566, 3555, 3615, 995, 1975, 5016, 8315, 31767, 13063, 3660, 29538, 39894, 2407, 11242, 5016, 23032, 3555, 4587, 9307, 2423, 13510, 966, 271, 10874, 2304, 40228, 11296, 4032, 9122, 2304, 7649, 39894, 2407, 11242, 5016, 20292, 2423, 33080, 271, 2423, 20666, 3615, 1829, 11622, 9122, 2304, 7649, 4032, 2423, 1422, 6672, 15447, 8032, 2655, 30544, 6055, 33753, 34105], "avg_logprob": -0.1734639795149787, "compression_ratio": 1.4113475177304964, "no_speech_prob": 0.0, "words": [{"start": 1406.85, "end": 1407.21, "word": "طبعا", "probability": 0.930908203125}, {"start": 1407.21, "end": 1407.41, "word": " احنا", "probability": 0.8642578125}, {"start": 1407.41, "end": 1407.77, "word": " الصورة", "probability": 0.8880208333333334}, {"start": 1407.77, "end": 1407.95, "word": " هذه", "probability": 0.28466796875}, {"start": 1407.95, "end": 1408.87, "word": " بتوضح", "probability": 0.9674072265625}, {"start": 1408.87, "end": 1411.95, "word": " طبقات", "probability": 0.9561767578125}, {"start": 1411.95, "end": 1412.47, "word": " ال", "probability": 0.9228515625}, {"start": 1412.47, "end": 1413.53, "word": " epidermis", "probability": 0.7627766927083334}, {"start": 1413.53, "end": 1417.49, "word": " جميعها", "probability": 0.9814453125}, {"start": 1417.49, "end": 1418.55, "word": " و", "probability": 0.94384765625}, {"start": 1418.55, "end": 1418.93, "word": " كمان", "probability": 0.8723958333333334}, {"start": 1418.93, "end": 1419.79, "word": " بتوضحلي", "probability": 0.9048828125}, {"start": 1419.79, "end": 1420.11, "word": " ال", "probability": 0.87744140625}, {"start": 1420.11, "end": 1420.81, "word": " dermis", "probability": 0.9501953125}, {"start": 1420.81, "end": 1421.09, "word": " ال", "probability": 0.91064453125}, {"start": 1421.09, "end": 1421.89, "word": " بالعيز", "probability": 0.50372314453125}, {"start": 1421.89, "end": 1423.11, "word": " كمان", "probability": 0.8610026041666666}, {"start": 1423.11, "end": 1423.37, "word": " و", "probability": 0.7890625}, {"start": 1423.37, "end": 1423.45, "word": " ال", "probability": 0.78466796875}, {"start": 1423.45, "end": 1424.33, "word": " subcutaneous", "probability": 0.9609375}, {"start": 1424.33, "end": 1426.57, "word": " هتكون", "probability": 0.9737955729166666}, {"start": 1426.57, "end": 1427.33, "word": " تحت", "probability": 0.971923828125}, {"start": 1427.33, "end": 1428.11, "word": " هنا", "probability": 0.9931640625}], "temperature": 1.0}, {"id": 62, "seek": 143971, "start": 1429.43, "end": 1439.71, "text": "بنشوف مكوناتها فى عندنا dead keratinocytes فى عندنا 3-ethamcorneum هنا شايفينها عندنا الوسيديا", "tokens": [3555, 1863, 8592, 38688, 3714, 4117, 2407, 8315, 2655, 11296, 6156, 7578, 43242, 8315, 3116, 19377, 22685, 905, 43673, 6156, 7578, 43242, 8315, 805, 12, 3293, 335, 19558, 716, 449, 34105, 13412, 995, 33911, 9957, 11296, 43242, 8315, 2423, 2407, 3794, 1829, 16254, 995], "avg_logprob": -0.36631943384806315, "compression_ratio": 1.218487394957983, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 1429.43, "end": 1430.09, "word": "بنشوف", "probability": 0.82012939453125}, {"start": 1430.09, "end": 1431.21, "word": " مكوناتها", "probability": 0.9039713541666666}, {"start": 1431.21, "end": 1432.09, "word": " فى", "probability": 0.51849365234375}, {"start": 1432.09, "end": 1432.45, "word": " عندنا", "probability": 0.6607666015625}, {"start": 1432.45, "end": 1432.59, "word": " dead", "probability": 0.6630859375}, {"start": 1432.59, "end": 1433.73, "word": " keratinocytes", "probability": 0.90234375}, {"start": 1433.73, "end": 1434.69, "word": " فى", "probability": 0.84228515625}, {"start": 1434.69, "end": 1434.99, "word": " عندنا", "probability": 0.96240234375}, {"start": 1434.99, "end": 1435.11, "word": " 3", "probability": 0.09747314453125}, {"start": 1435.11, "end": 1436.37, "word": "-ethamcorneum", "probability": 0.6832682291666666}, {"start": 1436.37, "end": 1437.05, "word": " هنا", "probability": 0.258056640625}, {"start": 1437.05, "end": 1437.91, "word": " شايفينها", "probability": 0.99072265625}, {"start": 1437.91, "end": 1438.71, "word": " عندنا", "probability": 0.955078125}, {"start": 1438.71, "end": 1439.71, "word": " الوسيديا", "probability": 0.5928955078125}], "temperature": 1.0}, {"id": 63, "seek": 146487, "start": 1440.97, "end": 1464.87, "text": "عنا ال granulosome وعنا ال spinous أو ال spinosome وعنا ال basal ليها هذه الطبقة اللي قلنا هي عبارة عن طبقة من ال ال columnar cells روح ال dermis الطبقة اللي تحتها هذه المكونات طبعتها", "tokens": [3615, 8315, 2423, 9370, 425, 329, 423, 4032, 3615, 8315, 2423, 6060, 563, 34051, 2423, 6060, 329, 423, 4032, 3615, 8315, 2423, 987, 304, 32239, 11296, 29538, 41950, 3555, 28671, 13672, 1829, 12174, 1211, 8315, 39896, 6225, 3555, 9640, 3660, 18871, 23032, 3555, 28671, 9154, 2423, 2423, 7738, 289, 5438, 12602, 2407, 5016, 2423, 33080, 271, 41950, 3555, 28671, 13672, 1829, 6055, 33753, 11296, 29538, 9673, 4117, 2407, 8315, 2655, 23032, 3555, 34268, 11296], "avg_logprob": -0.24520832777023316, "compression_ratio": 1.7453416149068324, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 1440.97, "end": 1441.47, "word": "عنا", "probability": 0.806640625}, {"start": 1441.47, "end": 1441.99, "word": " ال", "probability": 0.89111328125}, {"start": 1441.99, "end": 1443.13, "word": " granulosome", "probability": 0.45111083984375}, {"start": 1443.13, "end": 1444.35, "word": " وعنا", "probability": 0.9226888020833334}, {"start": 1444.35, "end": 1444.61, "word": " ال", "probability": 0.8974609375}, {"start": 1444.61, "end": 1445.41, "word": " spinous", "probability": 0.602783203125}, {"start": 1445.41, "end": 1445.69, "word": " أو", "probability": 0.63427734375}, {"start": 1445.69, "end": 1445.83, "word": " ال", "probability": 0.92333984375}, {"start": 1445.83, "end": 1446.77, "word": " spinosome", "probability": 0.6036783854166666}, {"start": 1446.77, "end": 1447.85, "word": " وعنا", "probability": 0.9757486979166666}, {"start": 1447.85, "end": 1448.43, "word": " ال", "probability": 0.96435546875}, {"start": 1448.43, "end": 1449.21, "word": " basal", "probability": 0.720458984375}, {"start": 1449.21, "end": 1449.67, "word": " ليها", "probability": 0.92431640625}, {"start": 1449.67, "end": 1450.05, "word": " هذه", "probability": 0.74609375}, {"start": 1450.05, "end": 1450.61, "word": " الطبقة", "probability": 0.96337890625}, {"start": 1450.61, "end": 1450.77, "word": " اللي", "probability": 0.8515625}, {"start": 1450.77, "end": 1450.99, "word": " قلنا", "probability": 0.8406575520833334}, {"start": 1450.99, "end": 1451.21, "word": " هي", "probability": 0.60791015625}, {"start": 1451.21, "end": 1451.67, "word": " عبارة", "probability": 0.9930419921875}, {"start": 1451.67, "end": 1451.93, "word": " عن", "probability": 0.99609375}, {"start": 1451.93, "end": 1452.33, "word": " طبقة", "probability": 0.9749348958333334}, {"start": 1452.33, "end": 1452.71, "word": " من", "probability": 0.9921875}, {"start": 1452.71, "end": 1453.29, "word": " ال", "probability": 0.98291015625}, {"start": 1453.29, "end": 1454.45, "word": " ال", "probability": 0.32568359375}, {"start": 1454.45, "end": 1455.05, "word": " columnar", "probability": 0.591064453125}, {"start": 1455.05, "end": 1455.99, "word": " cells", "probability": 0.9033203125}, {"start": 1455.99, "end": 1456.89, "word": " روح", "probability": 0.7802734375}, {"start": 1456.89, "end": 1457.93, "word": " ال", "probability": 0.61767578125}, {"start": 1457.93, "end": 1458.49, "word": " dermis", "probability": 0.575439453125}, {"start": 1458.49, "end": 1459.15, "word": " الطبقة", "probability": 0.8904622395833334}, {"start": 1459.15, "end": 1459.83, "word": " اللي", "probability": 0.8876953125}, {"start": 1459.83, "end": 1460.45, "word": " تحتها", "probability": 0.99462890625}, {"start": 1460.45, "end": 1461.03, "word": " هذه", "probability": 0.798828125}, {"start": 1461.03, "end": 1463.81, "word": " المكونات", "probability": 0.93251953125}, {"start": 1463.81, "end": 1464.87, "word": " طبعتها", "probability": 0.977783203125}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1465.5506875, "duration_after_vad": 1402.0149999999992}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..2766285d211b4e5f598a85b93f1d56fe486bba39
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/7VmmkW4mSRk_raw.srt
@@ -0,0 +1,1160 @@
+1
+00:00:04,930 --> 00:00:11,110
+بسم الله الرحمن الرحيم محاضرتنا اليوم الخامسة في
+
+2
+00:00:11,110 --> 00:00:16,270
+مجل ال anatomy introduction to anatomy or
+
+3
+00:00:16,270 --> 00:00:20,630
+essential human anatomy راح نتكلم اليوم عن ال skin
+
+4
+00:00:22,360 --> 00:00:28,540
+تقريبا ال skin يعتبر هو ال antigumentary system of
+
+5
+00:00:28,540 --> 00:00:32,120
+the body و ال largest تقريبا organ of the body
+
+6
+00:00:32,120 --> 00:00:38,380
+طوله بيجي في المتوسط من one point six or one point
+
+7
+00:00:38,380 --> 00:00:42,140
+nine يعني حوالي اتنين متر مربع من متر و نصف لاتنين
+
+8
+00:00:42,140 --> 00:00:50,650
+متر مربعan average size of adults لأن ال skin هو
+
+9
+00:00:50,650 --> 00:00:58,030
+عبارة عن الغطاء تبع الجسم اللى تحتى تندرج كل ال
+
+10
+00:00:58,030 --> 00:01:02,510
+organs Integumentary system describe the skin and
+
+11
+00:01:02,510 --> 00:01:09,390
+its appendages ملحقاته يعني ال skin و ملحقاته كلهم
+
+12
+00:01:09,390 --> 00:01:14,640
+مع بعض بنسميهم ال integumentary systemفي عندنا
+
+13
+00:01:14,640 --> 00:01:19,260
+نوعين من ال skin في عندنا ال thin skin اللى موجود
+
+14
+00:01:19,260 --> 00:01:25,800
+على معظم أجزاء الرسم لما فيها ال dorsum of the
+
+15
+00:01:25,800 --> 00:01:29,720
+hand and the foot وفي عندنا ال thick skin الخميل
+
+16
+00:01:29,720 --> 00:01:34,100
+اللى هو موجود في ال palm and plantar surface of
+
+17
+00:01:34,100 --> 00:01:37,340
+the foot طبعا ال thickness بترا واحد تن من واحد
+
+18
+00:01:37,340 --> 00:01:44,020
+لتلاتة مليو ال .. فيه thin skin و كمان من أربع
+
+19
+00:01:44,020 --> 00:01:46,380
+لخمسة ملي فيه thick skin
+
+20
+00:01:50,920 --> 00:01:54,920
+بالنسبة للـ function نعرف أنه الـ function of the
+
+21
+00:01:54,920 --> 00:02:01,440
+skin عبارة اتعلمنا من بداية حتى لما كنا أطفال في
+
+22
+00:02:01,440 --> 00:02:06,280
+المدارس كانوا بيقولوا أن الجلد هو خط دفاع الأول عن
+
+23
+00:02:06,280 --> 00:02:13,300
+الجسم يبقى هو من وضعه هو ال protection كمان
+
+24
+00:02:13,300 --> 00:02:15,640
+regulation of temperature
+
+25
+00:02:19,240 --> 00:02:23,000
+execration بيفرز العرق احنا لما بيطلع العرق على
+
+26
+00:02:23,000 --> 00:02:28,700
+الجسم بيطلع على عن طريق ال skin و synthesis of
+
+27
+00:02:28,700 --> 00:02:32,280
+vitamin D بنعرف انه احنا لما نتعرض على الشمس للشمس
+
+28
+00:02:32,280 --> 00:02:40,360
+بيصير في عندنا افرازلهرمون او لفيتامين D المهم
+
+29
+00:02:40,360 --> 00:02:45,680
+كتير في عملية انتصاص الكالسوم والبوتاسيوم وكمان ال
+
+30
+00:02:45,680 --> 00:02:49,800
+immune system هو ال first defense barrier of the
+
+31
+00:02:49,800 --> 00:02:55,440
+immune system يبقى نرجع نقول ان ال skin بيقدملي
+
+32
+00:02:55,440 --> 00:02:59,930
+اكتر من functionمنها temperature regulation منها
+
+33
+00:02:59,930 --> 00:03:06,850
+protection بمنع كمان ال .. بيحافظ على الجلد و على
+
+34
+00:03:06,850 --> 00:03:12,430
+الرطوبة بمنع السوائل أنها تطلع و نفس الوقت بيعطوني
+
+35
+00:03:12,430 --> 00:03:16,650
+إحساس و هذا كتير مهم لل sensory أنا بالنسبة لي إذا
+
+36
+00:03:16,650 --> 00:03:20,890
+حطت إيدي هنا بقدر أحس إذا كان هذا السطح بارد أو
+
+37
+00:03:20,890 --> 00:03:25,450
+سخن إذا كان شكت في إبرة أو في دبوس بحس إنه الإحساس
+
+38
+00:03:25,450 --> 00:03:30,990
+المنتشر علىكل الجلد هذا بيخليني .. بيعملي alerts،
+
+39
+00:03:30,990 --> 00:03:34,050
+بينبهني، دير بالك أنت اتلعتي على بيئة سخنة طلعت
+
+40
+00:03:34,050 --> 00:03:37,390
+على بيئة باردة، كل هذا عن طريق الإحساس، دعست على
+
+41
+00:03:37,390 --> 00:03:42,310
+مصمار، مسكت قبضت بشري مقبض سوحان، هذا كله من
+
+42
+00:03:42,310 --> 00:03:43,590
+الاسكن
+
+43
+00:03:45,370 --> 00:03:49,590
+يبقى في ال protection، إيش بدنا نقول في الموضوع ال
+
+44
+00:03:49,590 --> 00:03:53,670
+skin protection؟ عبارة عن physical barrier from
+
+45
+00:03:53,670 --> 00:04:01,130
+microorganism، بيمنع دخول أي إشي على داخل الجسم،
+
+46
+00:04:01,130 --> 00:04:06,720
+حاجزإذا كان إحنا أتعرضنا لمواد كيموية، إذا كان
+
+47
+00:04:06,720 --> 00:04:11,200
+استخدمنا ميّه نار، إيجي على إيدنا أي إشي ساق، أي
+
+48
+00:04:11,200 --> 00:04:16,620
+إشي chemical ممكن يعمل ليه؟ يدخل للجسم، فال skin
+
+49
+00:04:16,620 --> 00:04:19,540
+هذا بيوقف لعنده و بيوقفه
+
+50
+00:04:22,120 --> 00:04:27,200
+يعني إحنا لما بنخبط و أحنا مارقين أو أحنا ماشيين
+
+51
+00:04:27,200 --> 00:04:31,780
+في حفة الطاولة أو في حفة الكرسي ال skin هاد عامل
+
+52
+00:04:31,780 --> 00:04:35,040
+زي المخدة كده على الأشياء على طريق السبكوتانيا
+
+53
+00:04:35,040 --> 00:04:38,880
+الستشفر اللي موجودة فبيمنع ال mechanical trauma
+
+54
+00:04:38,880 --> 00:04:41,720
+prevent dehydration بيمنع السوائل و excessive
+
+55
+00:04:41,720 --> 00:04:45,920
+secretions بيمنعها أنها تطلع فبيمنع الجفاف protect
+
+56
+00:04:46,650 --> 00:04:50,690
+بها millennium excessive ultraviolet exposure طبعا
+
+57
+00:04:50,690 --> 00:04:53,790
+إحنا اللي ببقى متعرض لأشعة الشمس نبقى ماشيين جلدنا
+
+58
+00:04:53,790 --> 00:04:57,910
+كله إحنا من حب ربنا يعني إحنا النساء المسلمات بكون
+
+59
+00:04:57,910 --> 00:05:02,190
+جسمهم بطة مع عدى الوجه هو الكفان السنة كانت منأو
+
+60
+00:05:02,190 --> 00:05:07,570
+الحكمة من كشف الوجه والكفان هو أن أكتر مناطق هذه
+
+61
+00:05:07,570 --> 00:05:10,450
+ممكن أنها تعمل synthesis تعرضها للشمس يعمل
+
+62
+00:05:10,450 --> 00:05:16,230
+synthesis للافيتامين دي هي الإيدين والوجه لكن
+
+63
+00:05:16,230 --> 00:05:20,650
+الجسم إذا اتعرض ل excessive sun light ممكن يتعرض
+
+64
+00:05:20,650 --> 00:05:28,330
+لburn لكن الجلد هو اللي بيحمي الجسم من ال sun burn
+
+65
+00:05:28,330 --> 00:05:33,150
+أما ال functionالتانية فهي ال sensation ال
+
+66
+00:05:33,150 --> 00:05:37,730
+sensation اللي انت شعر الواسع ل ال sensory organs
+
+67
+00:05:37,730 --> 00:05:47,650
+أو ل ال tactile tissue اللي بتخلينا نحس بكل إشي
+
+68
+00:05:47,650 --> 00:05:52,110
+ممكن إحنا نتعرض عليهنتعرض له somatic sensory
+
+69
+00:05:52,110 --> 00:05:57,490
+receptors detect stimuli that permit use detect ال
+
+70
+00:05:57,490 --> 00:06:01,970
+pressure ال touch ال temperature ال pain all the
+
+71
+00:06:01,970 --> 00:06:05,550
+general sensations يعني احنا لو مسيكنا و احنا
+
+72
+00:06:05,550 --> 00:06:10,470
+مغمضين بيدنا خمس شكل بنحس مسيكنا قلم بنعرف انه هذا
+
+73
+00:06:10,470 --> 00:06:13,470
+قلم مسيكنا الجوال هذا جوالي ولا مش جوالي حتى و انا
+
+74
+00:06:13,470 --> 00:06:17,430
+مش شايفه اه بعرف لاني عارف احزم جوالي و شكله كل
+
+75
+00:06:17,430 --> 00:06:22,190
+الاحساس بيصير عن طريقلـ skin لو وقع على رجل ناشي
+
+76
+00:06:22,190 --> 00:06:25,290
+طبعا الناس اللي بتفقد الاحساس هذه بتكون عرضة اكتر
+
+77
+00:06:25,290 --> 00:06:31,190
+ل ال injury كمان
+
+78
+00:06:31,190 --> 00:06:36,110
+ال skin فيه خاصية ل flexibility وهي بيساعد على ال
+
+79
+00:06:36,110 --> 00:06:40,150
+elasticity هذه بيساعد على تغيير الشكل يعني انا بدي
+
+80
+00:06:40,150 --> 00:06:43,150
+اغنط ايدي بدي افتح ايدي لو لإن ال skin عندي
+
+81
+00:06:43,150 --> 00:06:47,110
+flexible كان انا مقدرش اغنط ايدي لو اضطربنا ان شخص
+
+82
+00:06:47,110 --> 00:06:51,400
+اخد مثلا جروحبصار عنده جروح في هذه المنطقة بيصير
+
+83
+00:06:51,400 --> 00:06:56,060
+فردة إيده هذه صعبة ليش؟ لأنه بيصير ال skin مش
+
+84
+00:06:56,060 --> 00:06:59,300
+flexible فمعناه أني أنا الحركات اللي بعملها هذه
+
+85
+00:06:59,300 --> 00:07:02,440
+كلها اللي بيسمحلي فيها اللي بيعطيني ال range فيها
+
+86
+00:07:02,440 --> 00:07:07,820
+صحيح المدى العضلي لكن كمان ال skin flexibility of
+
+87
+00:07:07,820 --> 00:07:11,060
+the skin و ال execrations اللي هي ال water و ال
+
+88
+00:07:11,060 --> 00:07:14,340
+urea و كل الأشياء السموم اللي بتطلع عن طريق ال
+
+89
+00:07:14,340 --> 00:07:18,980
+sweetالهادية بتخلص منها الجسم اتكلم ال sweating
+
+90
+00:07:18,980 --> 00:07:24,460
+glands هي تقريبا مكيف الجسم اللي بيخلي الجسم يتعرق
+
+91
+00:07:24,460 --> 00:07:29,700
+فبيقلل من حرارة الداخلية للجسم ال immune ليش؟ لإن
+
+92
+00:07:29,700 --> 00:07:33,720
+في عنا حاجة اسمها longer handsسلز هذه طبيعتها
+
+93
+00:07:33,720 --> 00:07:38,900
+بتساعد في الimmune system فهي فيها الفاغوسيتوس أو
+
+94
+00:07:38,900 --> 00:07:43,480
+الفاغوسيتك سلز بتعمل destroying البكتيريا نلاحظ ان
+
+95
+00:07:43,480 --> 00:07:47,040
+احنا اول ما بنجريها او هدا بتبدأ عندنا الحمراء و
+
+96
+00:07:47,040 --> 00:07:52,500
+بتبدأ تصير في عملية هجوم من ال white blood cells
+
+97
+00:07:52,500 --> 00:07:57,840
+في المكان حتى انها تمنع دخول البكتيريا وتخلص منها
+
+98
+00:08:00,240 --> 00:08:05,300
+طبعا الـ heat loss تقريبا احنا 80% of heat loss
+
+99
+00:08:05,300 --> 00:08:08,960
+occurs through the skin لأن الجسم إذا كان في جو
+
+100
+00:08:08,960 --> 00:08:12,960
+حار زي هيك دلو محتفظ بالحرارة محتفظ بالحرارة بعد
+
+101
+00:08:12,960 --> 00:08:17,920
+هيك إيش بيصير؟ خلينا نقول بالعربي بتنطق ال organs
+
+102
+00:08:17,920 --> 00:08:20,780
+يعني مش معقول إنهم دلوا ارتفاع مستمر في درجات
+
+103
+00:08:20,780 --> 00:08:25,340
+الحرارة فالجسم بيخلص ال .. ال gel بيخلص الجسم من
+
+104
+00:08:25,340 --> 00:08:30,470
+الحرارة عن طريق ال sweatingبضمن 20% occurred
+
+105
+00:08:30,470 --> 00:08:33,830
+through the mucous والرسبيراتوري والديجستف
+
+106
+00:08:33,830 --> 00:08:38,310
+والريونارياتريكس أما ال skin بياخد 80% من تخلص
+
+107
+00:08:38,310 --> 00:08:44,110
+الجسم من الحرارة الزائدةروح لا إشي مهم كتير في
+
+108
+00:08:44,110 --> 00:08:47,970
+عندنا three layers of skin هذا ال skin اللي إحنا
+
+109
+00:08:47,970 --> 00:08:52,550
+شايفينه اللي بنمسكه سواء كان رقيق أو كان أكميل فهو
+
+110
+00:08:52,550 --> 00:08:56,430
+بتكون من تلاتة layers اتنين منهم هي layers of skin
+
+111
+00:08:56,430 --> 00:08:59,570
+و ال layer بتاع اللي هو subcutaneous layer هو
+
+112
+00:08:59,570 --> 00:09:03,770
+أحيانا ما بيعتبر هو دائما بيعتبر part of the skin
+
+113
+00:09:03,770 --> 00:09:06,850
+يبقى في عندنا ال epidermis في عندنا ال dermis في
+
+114
+00:09:06,850 --> 00:09:11,290
+عندنا subcutaneous layersالsubcutaneous اللي هو
+
+115
+00:09:11,290 --> 00:09:16,470
+sub كلمة sub دايما تعني تحت تحت الجلد طبقة من
+
+116
+00:09:16,470 --> 00:09:20,450
+الدهون بتكون تحت الجلد يبقى beneath the dermis not
+
+117
+00:09:20,450 --> 00:09:26,930
+part of the skin زي ما احنا شايفين هذا الشكل هنوضح
+
+118
+00:09:26,930 --> 00:09:31,030
+اكتر ونتعرف على ال epidermis كلمة epidermis means
+
+119
+00:09:31,030 --> 00:09:36,670
+فوقفوق above اللي بيه الطبقة الخارجية طبعا الطبقة
+
+120
+00:09:36,670 --> 00:09:40,830
+الخارجية بتكون فيش فيها blood vessels keratinized
+
+121
+00:09:40,830 --> 00:09:45,530
+فيها ال protein ال keratin thickenest on the palm
+
+122
+00:09:45,530 --> 00:09:48,670
+and the sole قلنا في عندنا نوعين من ال skin في
+
+123
+00:09:48,670 --> 00:09:51,530
+عندنا thick skin و في عندنا thin skin ال thick
+
+124
+00:09:51,530 --> 00:09:57,390
+skin بيكون في palm of the foot and the sole of the
+
+125
+00:09:57,390 --> 00:10:04,390
+palm of the hand and the sole of the footالـ
+
+126
+00:10:04,390 --> 00:10:08,090
+melanocytes provide melanin الـ melanin هو الصبغة
+
+127
+00:10:08,090 --> 00:10:13,570
+اللي بتحقق يعني بيكون على أثرها تركيزها نوع لون ال
+
+128
+00:10:13,570 --> 00:10:17,750
+skin إذا كان هذا بشرته بيضا، هذا بشرته صمرة، هذا
+
+129
+00:10:17,750 --> 00:10:21,890
+بشرته أمحي، هذا بشرته سوداء يكون تركيز ال melanin
+
+130
+00:10:21,890 --> 00:10:26,610
+فيها أكتر طبعا في حاجة اسمها Basel أو Basement
+
+131
+00:10:26,610 --> 00:10:30,610
+Membrane اتكلمنا على ال epithelial cells في المرات
+
+132
+00:10:30,610 --> 00:10:34,780
+السابقة ال epithelial cells قلنا تبقىالاخيرة أو
+
+133
+00:10:34,780 --> 00:10:38,080
+التحتانية هي عبارة عن Basel سل أو بنسميها
+
+134
+00:10:38,080 --> 00:10:44,480
+Basements ونوع ال ابيتاليا السل اللي موجودة
+
+135
+00:10:44,480 --> 00:10:52,460
+stratified squamous لأنها هي شكلها كده مسطح طبعا
+
+136
+00:10:52,460 --> 00:10:58,180
+في عندناأنواع الـ cells اللي بتكون ال epidermis في
+
+137
+00:10:58,180 --> 00:11:02,140
+عينها الكيراتونسايت والملانوسايت والـ Langerhans
+
+138
+00:11:02,140 --> 00:11:08,880
+كل واحدة منهم لها وظيفة الكيراتونسايت عبارة عن 90%
+
+139
+00:11:08,880 --> 00:11:12,760
+من هذه ال cells اللي موجودة ال principle structure
+
+140
+00:11:12,760 --> 00:11:17,860
+element for outer skin بتكون الطبقة الخارجية من ال
+
+141
+00:11:17,860 --> 00:11:21,660
+skin أما الملانوسايتهي الـ Pigmentation اللي بتعمل
+
+142
+00:11:21,660 --> 00:11:27,260
+لون الجلد products producing 5% of the total
+
+143
+00:11:27,260 --> 00:11:31,840
+contribute and scale color filter ال ultraviolet
+
+144
+00:11:31,840 --> 00:11:37,100
+light هي اللي بتساعد على الحفاظ على الجلد من ال
+
+145
+00:11:37,100 --> 00:11:41,720
+ultraviolet اللي بتجينا من الشمسlarger hands هي
+
+146
+00:11:41,720 --> 00:11:45,180
+الـdendritic branches عبارة عن antigen
+
+147
+00:11:45,180 --> 00:11:51,700
+-representing cell ال ABCs they play the role in
+
+148
+00:11:51,700 --> 00:11:56,380
+immune response إذا تعرض الجسم أو الجلد لأي insult
+
+149
+00:11:56,380 --> 00:12:02,700
+يعني insect مثلا بعت إجتنا نحلة إجتنا أي insect
+
+150
+00:12:02,700 --> 00:12:07,970
+إجت وقرستنا فعلى طول بتشتغل longer handsوبتعمل ليه
+
+151
+00:12:07,970 --> 00:12:13,550
+بتزود المناعة في هذا المكان أما ال epidermis كمان
+
+152
+00:12:13,550 --> 00:12:17,190
+بتكون من layers يعني هي طبقة رقيقة صحيح لكن بتكون
+
+153
+00:12:17,190 --> 00:12:21,430
+من layers في حالة ال thick skin بتكون خمسة layers
+
+154
+00:12:21,430 --> 00:12:25,670
+في حالة ال thin skin بتكون أربعة layers ال layers
+
+155
+00:12:25,670 --> 00:12:32,750
+هذه عبارة عن لو أخدناها من السطح للأسفل فعنا ال
+
+156
+00:12:32,750 --> 00:12:38,220
+striatum corneumوالسترياتم لوسيديا والسترياتم
+
+157
+00:12:38,220 --> 00:12:43,200
+اللانيروزام والاسفاينس والبيزل ناخدهم واحدة واحدة
+
+158
+00:12:43,200 --> 00:12:54,440
+ونتعرف عليهم الآن البيزل
+
+159
+00:12:54,440 --> 00:12:59,430
+استرياتمالطبقة القاعدية إحنا بنسميها عبارة عن
+
+160
+00:12:59,430 --> 00:13:02,970
+single layer columnar إيش يعني columnar يعني شكل
+
+161
+00:13:02,970 --> 00:13:07,950
+ال cells بهذا الشكل هي طبقة واحدة لكن ال cells
+
+162
+00:13:07,950 --> 00:13:13,790
+columnar تمام؟
+
+163
+00:13:17,090 --> 00:13:20,870
+زي ما اتعرفنا في محاضرتنا تبع الـ Epithelium
+
+164
+00:13:20,870 --> 00:13:27,490
+Columnar cells under cosmetosis و migration بتتقسم
+
+165
+00:13:27,490 --> 00:13:35,650
+و بتروح بتهاجر حتى تصل للسطح و تموت أما الشوكية لـ
+
+166
+00:13:35,650 --> 00:13:42,360
+striatum spinosum اللي هي Spiny layer calledSales
+
+167
+00:13:42,360 --> 00:13:46,560
+arranged in eight to ten يعني هنا الأول ال layer
+
+168
+00:13:46,560 --> 00:13:50,240
+الأولاني أو ال base بتكون من layer واحد أما ال
+
+169
+00:13:50,240 --> 00:13:55,800
+layer التاني بتكون من eight to ten layers
+
+170
+00:13:58,910 --> 00:14:03,590
+شكلها بيكون عامل زي ال spine يعني بيكون مبوظ كده
+
+171
+00:14:03,590 --> 00:14:09,770
+spinous تمام into spiny shape cell rich in RNA
+
+172
+00:14:09,770 --> 00:14:16,190
+فيها ال RNA أما ال granulosome أو ال striatum
+
+173
+00:14:18,430 --> 00:14:22,890
+Cells arranged two to four layers filled with
+
+174
+00:14:22,890 --> 00:14:27,930
+keratin هي ليه؟ Granules contains high level of
+
+175
+00:14:27,930 --> 00:14:35,910
+lysomal enzymes ليزومال؟ Enzyme أما لسريات
+
+176
+00:14:35,910 --> 00:14:39,590
+الملوسيديا فهي clear layer cell filled with
+
+177
+00:14:39,590 --> 00:14:45,240
+keratin precursor called elidinabsent in the thin
+
+178
+00:14:45,240 --> 00:14:51,080
+skin فهذه الطبقة الو سيديام مش موجودة في ال skin
+
+179
+00:14:51,080 --> 00:14:57,300
+thin أما ال sternum corium اللي هي horny layers
+
+180
+00:14:57,300 --> 00:15:01,780
+مُس superficial layer dead cells filled with
+
+181
+00:15:01,780 --> 00:15:09,980
+keratin ايرياها دي الطبقة الخارجية لل skin
+
+182
+00:15:16,070 --> 00:15:19,070
+طبعا في حاجة اسمها dermal and epidermal function
+
+183
+00:15:19,070 --> 00:15:24,250
+بين الديرم وبين الepiderm في انه junction بنوصل
+
+184
+00:15:24,250 --> 00:15:30,170
+البعض عبارة عن placement membrane specialized
+
+185
+00:15:30,170 --> 00:15:35,370
+fibers element and polysaccharide gel served as
+
+186
+00:15:35,370 --> 00:15:42,990
+glue glue اش يعني يعني زي صمغية glue صمغ glue
+
+187
+00:15:43,290 --> 00:15:46,730
+the epidermis to the dermis below junctions of
+
+188
+00:15:46,730 --> 00:15:51,730
+partial barrier to passage of some cells and large
+
+189
+00:15:51,730 --> 00:15:54,870
+molecules يعني عبارة عن حاجز هنا الحاجز بين
+
+190
+00:15:54,870 --> 00:16:00,050
+الديرمس وبين ال epidermis نروح للديرمس sometimes
+
+191
+00:16:00,050 --> 00:16:04,670
+called true skin الحقيقة اللي الأدمة بيسموها هناك
+
+192
+00:16:04,670 --> 00:16:08,310
+البشرة ال epidermis البشرة أما هذه بيسموها الأدمة
+
+193
+00:16:09,230 --> 00:16:12,910
+much thicker than epidermis and lies beneath it
+
+194
+00:16:12,910 --> 00:16:16,970
+أخمل شوية من epidermis بتكون هو عبارة من collagen
+
+195
+00:16:16,970 --> 00:16:21,570
+fibers and elastin fibers هنشوفه شوية gives
+
+196
+00:16:21,570 --> 00:16:26,430
+strength to skin بأول ال skin serve as re-servers
+
+197
+00:16:26,430 --> 00:16:30,730
+area for storage of water and electrolyte بعبارة
+
+198
+00:16:30,730 --> 00:16:36,270
+عن هو storage للميه و ال electrolytes epidermis
+
+199
+00:16:37,360 --> 00:16:41,880
+تقريبا ال thickness تبقى من واحد لاثنين ميلي في
+
+200
+00:16:41,880 --> 00:16:48,900
+ديرمال papilla هليمات ال danceDense Epidermis to
+
+201
+00:16:48,900 --> 00:16:53,380
+the underlying tissue هو عبارة عن الوصلة ما بين ال
+
+202
+00:16:53,380 --> 00:16:57,260
+Epidermis و بين ال underlying tissue بتكون من ال
+
+203
+00:16:57,260 --> 00:17:01,540
+regular dense connective tissue في muscle cells في
+
+204
+00:17:01,540 --> 00:17:05,120
+nerve cells specialised sensory receptors في blood
+
+205
+00:17:05,120 --> 00:17:09,820
+vessels في hair follicles و egg glands طبعا الصورة
+
+206
+00:17:09,820 --> 00:17:16,260
+هنا بتوضحتقريبا ال dermis ال epidermis و ال dermis
+
+207
+00:17:16,260 --> 00:17:20,580
+subcutaneous تشوف مضايق أنه ال dermis بيحتوي على
+
+208
+00:17:20,580 --> 00:17:25,320
+إذا طلعنا هنا بنشوف ال papillae اللي هي عاملة زي
+
+209
+00:17:25,320 --> 00:17:30,320
+التعرش بهذا الشكل عشان تصير داخل ال dermis مع ال
+
+210
+00:17:30,320 --> 00:17:32,340
+epidermis
+
+211
+00:17:34,770 --> 00:17:40,590
+و في عندنا كل الـ Receptors هاي الموجودة و في
+
+212
+00:17:40,590 --> 00:17:43,910
+عندنا الـ glands زي الـ sweating gland في عندنا ال
+
+213
+00:17:43,910 --> 00:17:47,830
+hair follicles ال sweating gland هي عاملة زي تيوب
+
+214
+00:17:47,830 --> 00:17:54,050
+اللي بتطلع ال sweating على سطح الجلد فيها هنا ال
+
+215
+00:17:54,050 --> 00:17:57,590
+subcutaneous tissue ما تحت ال dermis
+
+216
+00:18:05,160 --> 00:18:07,900
+Condamnus contains various structures فيه ال
+
+217
+00:18:07,900 --> 00:18:11,600
+erecto-pili muscle and hair follicles، إذا بلاحظ
+
+218
+00:18:11,600 --> 00:18:15,980
+أن الشخص لو خاف أو برد بتلاقي الشعر للجسم، احنا
+
+219
+00:18:15,980 --> 00:18:22,620
+عارفين أن كل الجسم بيتغطى بشعرإلا بعد المناطق في
+
+220
+00:18:22,620 --> 00:18:26,540
+موجود الجسم، هلقيتها؟ لو شخص خافة بحس إنه شعر
+
+221
+00:18:26,540 --> 00:18:30,860
+الجسم و كأنه بيوقف، بحيث بنقول أب شعر بدني كده،
+
+222
+00:18:30,860 --> 00:18:34,760
+بنقول أشعرتي، إيش يعني؟ هذي ال .. ال rector بال
+
+223
+00:18:34,760 --> 00:18:38,260
+lie muscles هي اللي بتعمل contraction فبيوقف،
+
+224
+00:18:38,260 --> 00:18:42,620
+contraction فبيوقف شعر الجسمSensory receptors
+
+225
+00:18:42,620 --> 00:18:46,640
+موجود فيها sweating and sebaceous gland اللي موجود
+
+226
+00:18:46,640 --> 00:18:54,170
+فيها ال gland الدهنيةالـBlood vessels ريتش فاسكولر
+
+227
+00:18:54,170 --> 00:18:56,790
+supply plays a critical role in temperature
+
+228
+00:18:56,790 --> 00:19:00,470
+regulation طيب و احنا قولنا كل ما كان فيه blood
+
+229
+00:19:00,470 --> 00:19:04,330
+supply أكتر كل ما الجسم الجلد كان أسخن طب عن ال
+
+230
+00:19:04,330 --> 00:19:07,190
+layers احنا بنبنع عن two layers ال papillary layer
+
+231
+00:19:07,190 --> 00:19:12,230
+و ال reticular layer ال papillary layer compose of
+
+232
+00:19:12,230 --> 00:19:15,790
+dermal papillae that protect into epidermis
+
+233
+00:19:17,070 --> 00:19:21,450
+contains collagen and elastin الcollagen بيعطي
+
+234
+00:19:21,450 --> 00:19:25,930
+strength و ال elastin بيعطي مرونة ال collagen
+
+235
+00:19:25,930 --> 00:19:31,770
+لإنها fibers و fibers قوية فهي بتعطي ال strength
+
+236
+00:19:31,770 --> 00:19:36,130
+لل skin بتقوي أما ال elastic fibers بتعطيني
+
+237
+00:19:36,130 --> 00:19:39,970
+المرونة عشان أنا أقدر أغمض و أفتح و أمد إيدي و
+
+238
+00:19:39,970 --> 00:19:44,150
+أرفعها أوطي و أقوم كل الحركات اللي إحنا بنعملها
+
+239
+00:19:44,370 --> 00:19:49,750
+contains the dermal-epidermic junction for ionic
+
+240
+00:19:49,750 --> 00:19:53,110
+pattern that gives individual fingertips، عارفين
+
+241
+00:19:53,110 --> 00:19:56,090
+ال fingers؟ احنا كل واحد فيه بصمة، فينا على
+
+242
+00:19:56,090 --> 00:20:03,810
+الأصابع كل جسم له بصمةالـ reticular layer عبارة عن
+
+243
+00:20:03,810 --> 00:20:08,910
+disc interlaced يعني هي عبارة عن fibers،
+
+244
+00:20:08,910 --> 00:20:14,070
+collagenous fibers لكن هي متشابكة و سميكة and
+
+245
+00:20:14,070 --> 00:20:17,970
+elastic fibers to make the skin tough and
+
+246
+00:20:17,970 --> 00:20:24,190
+stretchable يعني بتخلينا تكون ال skin في إمكانية
+
+247
+00:20:24,190 --> 00:20:28,810
+لإنه ينمغط، عشان ينمغط أن يكون فيه نوع من المرونة
+
+248
+00:20:29,780 --> 00:20:35,600
+في النحج اسمها lines of cleavage lines of cleavage
+
+249
+00:20:35,600 --> 00:20:42,380
+عبارة عن خطوط موجودة في ال skin بتحدد ال skin
+
+250
+00:20:42,380 --> 00:20:45,860
+identifying the predominant orientation of
+
+251
+00:20:45,860 --> 00:20:50,000
+collagen fibers clinically and surgically
+
+252
+00:20:50,000 --> 00:20:53,240
+significant because cut can result in a slow
+
+253
+00:20:53,240 --> 00:20:58,340
+healingand increase scarring تطلع على الصورة اللي
+
+254
+00:20:58,340 --> 00:21:04,520
+قدامنا بنلاقي انه ال cleavage lines موجودة طولية
+
+255
+00:21:04,520 --> 00:21:12,160
+هنا في ال upper and lower limb وموجودة عرضية في ال
+
+256
+00:21:12,160 --> 00:21:20,080
+trunk طيب هاي أشفيدتها لو صار cut في اتجاه
+
+257
+00:21:21,690 --> 00:21:26,790
+الـ vipers بيكون سهل الالتئام لكن لو أصار cuts
+
+258
+00:21:26,790 --> 00:21:31,850
+perpendicular فالمون
+
+259
+00:21:31,850 --> 00:21:37,110
+بيصير صعب الالتئام بيصير scarring بيصير scar فهذه
+
+260
+00:21:37,110 --> 00:21:43,120
+مهمة كتير لل surgeon أنه يعرف اتجاههالـ lines هذه
+
+261
+00:21:43,120 --> 00:21:47,860
+حتى يساعدوا في اتخاذ القرار في أي اتجاه هو يفتح
+
+262
+00:21:47,860 --> 00:21:51,960
+طولي ولا عردي طبعا كل ما كان في اتجاه ال collagen
+
+263
+00:21:51,960 --> 00:21:59,570
+fibers كل ما كان ال healing أسرع و أفضلالـ dermis
+
+264
+00:21:59,570 --> 00:22:06,270
+remains a scar و ال dermal growth and repair ال
+
+265
+00:22:06,270 --> 00:22:11,690
+dermis regenerates itself as does epidermis يعني
+
+266
+00:22:11,690 --> 00:22:16,350
+بيصير regeneration للepidermis
+
+267
+00:22:16,350 --> 00:22:22,010
+في عندنا ال subcutaneous layer ال subcutaneous
+
+268
+00:22:22,010 --> 00:22:29,380
+layer عبارة عن طبقةالـ Dermis بتعملي زي فاشية
+
+269
+00:22:29,380 --> 00:22:35,820
+نسميها Hypodermis عبارة عن موز connective tissue،
+
+270
+00:22:35,820 --> 00:22:40,920
+adipose، insulates، and measure blood vessels بتمر
+
+271
+00:22:40,920 --> 00:22:46,980
+فيها، فيها خلايا دهنية وكمان بتعملي عملية عزل وفصل
+
+272
+00:22:46,980 --> 00:22:52,180
+ما بين ال subcutaneous بين ال dermis و ال layers
+
+273
+00:22:52,180 --> 00:22:53,340
+اللي تحتها
+
+274
+00:22:56,680 --> 00:22:59,480
+الـ hypodermis also called subcutaneous layer or
+
+275
+00:22:59,480 --> 00:23:03,100
+superficial fascia لأنه في عندنا deep fascia ال
+
+276
+00:23:03,100 --> 00:23:06,720
+superficial fascia اللي بتكون تحت ال skin على طول
+
+277
+00:23:06,720 --> 00:23:12,400
+هي عبارة عن صموت كاملة لبسها الجسم من الجمجمة لحد
+
+278
+00:23:12,400 --> 00:23:18,460
+اللوارق limbs forming عندنا deep to the dermis تحت
+
+279
+00:23:18,460 --> 00:23:22,200
+ال dermis forming connection between the skin and
+
+280
+00:23:22,200 --> 00:23:27,210
+other structure هي it's not part of the skinطبعا
+
+281
+00:23:27,210 --> 00:23:31,950
+احنا الصورة هذه بتوضح طبقات
+
+282
+00:23:31,950 --> 00:23:37,490
+ال epidermis جميعها
+
+283
+00:23:37,490 --> 00:23:43,450
+و كمان بتوضحلي ال dermis ال بالعيز كمان و ال
+
+284
+00:23:43,450 --> 00:23:52,450
+subcutaneous هتكون تحت هنابنشوف مكوناتها فى عندنا
+
+285
+00:23:52,450 --> 00:23:57,050
+dead keratinocytes فى عندنا 3-ethamcorneum هنا
+
+286
+00:23:57,050 --> 00:24:04,610
+شايفينها عندنا الوسيدياعنا ال granulosome وعنا ال
+
+287
+00:24:04,610 --> 00:24:10,050
+spinous أو ال spinosome وعنا ال basal ليها هذه
+
+288
+00:24:10,050 --> 00:24:14,450
+الطبقة اللي قلنا هي عبارة عن طبقة من ال ال
+
+289
+00:24:14,450 --> 00:24:21,030
+columnar cells روح ال dermis الطبقة اللي تحتها هذه
+
+290
+00:24:21,030 --> 00:24:24,870
+المكونات طبعتها
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg.srt
new file mode 100644
index 0000000000000000000000000000000000000000..3e9a87ca433db81cecc6eb5ec5cb5056d8bd8b49
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg.srt
@@ -0,0 +1,1350 @@
+1
+00:00:04,910 --> 00:00:08,090
+بسم الله الرحمن الرحيم اليوم بدنا نكمل الموضوع ال
+
+2
+00:00:08,090 --> 00:00:12,910
+skin أو الـ Integumentary System وشرحنا في
+
+3
+00:00:12,910 --> 00:00:16,850
+المحاضرة السابقة طبقات الـ skin: الـ epidermis و
+
+4
+00:00:16,850 --> 00:00:23,250
+dermis و subcutaneous tissue وقلنا أن الـ skin هو
+
+5
+00:00:23,250 --> 00:00:28,090
+اللي بيحدد الـ color، color of the body، طبعا بتحدد
+
+6
+00:00:28,090 --> 00:00:33,230
+عن طريق الـ pigmentation أو الـ amount of melanin،
+
+7
+00:00:33,230 --> 00:00:37,570
+في عندنا أكثر من عامل بيحدد لون الـ skin، في عندنا
+
+8
+00:00:37,570 --> 00:00:40,830
+genetic factors، في عندنا environmental factors،
+
+9
+00:00:40,830 --> 00:00:43,090
+في عندنا physiological factors
+
+10
+00:00:44,950 --> 00:00:49,930
+عبارة عن الـ .. لو تكلمنا عن الـ everything مثلا صار
+
+11
+00:00:49,930 --> 00:00:55,650
+في عندنا احمرار في الـ .. في الجسم، معناه إنه صار
+
+12
+00:00:55,650 --> 00:00:59,530
+فيه تركيز للـ blood في المنطقة، بنسميها حاجة اسمها
+
+13
+00:00:59,530 --> 00:01:03,130
+vasodilation، ممكن تصير vasodilation، ممكن تصير constriction،
+
+14
+00:01:03,130 --> 00:01:07,920
+بتسكر الأوعية الدموية، في عندنا accumulation of
+
+15
+00:01:07,920 --> 00:01:11,240
+carotene أو jaundice بيصير في عندنا مشكلة مثلا في
+
+16
+00:01:11,240 --> 00:01:16,300
+الـ .. في الكبد أو تركيز لـ .. أو بيصير اصفرار اللي
+
+17
+00:01:16,300 --> 00:01:22,450
+بيسميه jaundice اللي هو الـ bilirubin مثلا بيزيد، بيخلّي لون الـ
+
+18
+00:01:22,450 --> 00:01:27,730
+skin أصفر، أو العين، بياض العين بيصير أصفر، في
+
+19
+00:01:27,730 --> 00:01:30,590
+عندنا genetic factors، ليش بنقول في ناس بيض، في ناس
+
+20
+00:01:30,590 --> 00:01:36,510
+سمر، في حدا لونه أسود، في ناس لونهم قمحي، هذا
+
+21
+00:01:36,510 --> 00:01:41,110
+بيصير أنه الاثنين مثلا الأب والأم بيض، فهذا أبنائهم
+
+22
+00:01:41,110 --> 00:01:44,910
+بيطلعوا بيض، الأب والأم سمر، أبنائهم بيطلعوا سمر،
+
+23
+00:01:44,910 --> 00:01:49,820
+وهكذا، يبقى في عندنا الـ Genetic Factors: Varying
+
+24
+00:01:49,820 --> 00:01:52,980
+Amounts of Melanin، Varying Size of Melanin
+
+25
+00:01:52,980 --> 00:01:57,960
+Granules، أما الـ Environmental Factors فالتعرض للـ
+
+26
+00:01:57,960 --> 00:02:01,660
+sunlight و الـ ultraviolet و الـ X-Ray بيعطينا
+
+27
+00:02:01,660 --> 00:02:06,640
+darkness للميلانين، بيصير حاجة اسمها Pigmentation of
+
+28
+00:02:06,640 --> 00:02:13,640
+Melanin، أما بالنسبة لتحديد
+
+29
+00:02:13,640 --> 00:02:18,100
+اللون عن طريق الميلانين، يبقى الـ Basic determinants
+
+30
+00:02:18,100 --> 00:02:23,720
+of skin color عبارة عن الـ quality، الـ quantity
+
+31
+00:02:23,720 --> 00:02:27,520
+of الميلانين، الـ type and distribution of الميلانين
+
+32
+00:02:27,520 --> 00:02:31,680
+بيحدد اللون، الـ beta-carotene عبارة عن group  في الـ
+
+33
+00:02:31,680 --> 00:02:35,820
+pigmentation from the food، also contribute in skin
+
+34
+00:02:35,820 --> 00:02:44,480
+color، ممكن يتأثر لون الجلد الـ hemoglobin، عبارة
+
+35
+00:02:44,480 --> 00:02:49,580
+عن الـ .. الـ redness اللي بيجي على الـ skin أو اللي
+
+36
+00:02:49,580 --> 00:02:52,440
+بيبين على الـ skin، الـ redder .. الـ redder skin
+
+37
+00:02:52,440 --> 00:02:56,920
+color when blood flow to the skin increases، ممكن
+
+38
+00:02:56,920 --> 00:03:01,500
+صار في عندي تدفق للدم في منطقة معينة، فبتصير هذه
+
+39
+00:03:01,500 --> 00:03:06,220
+المنطقة لونها أحمر، لو صار الدم إجا على المنطقة
+
+40
+00:03:06,220 --> 00:03:10,220
+اللي ما كان فيه oxygen فبيصير لونها أزرق أو قريب
+
+41
+00:03:10,220 --> 00:03:17,020
+على لون بنفسجي، لو كان في عندنا ضربات أو كذا في
+
+42
+00:03:17,020 --> 00:03:21,540
+الجسم، فبنلاقي أنه بتيجي حاجة زي الـ rainbow أو قزح
+
+43
+00:03:21,540 --> 00:03:25,860
+قوس قزح على الجسم، بتطلع إنه إحنا بنخبط في المكان و
+
+44
+00:03:25,860 --> 00:03:29,180
+بناخدش بالنا من الضربة اللي كانت بعدها، فما بنطلع، ممكن
+
+45
+00:03:29,180 --> 00:03:32,720
+نلاقي صار في عندي زي ألوان الطيف موجودة على الجسم
+
+46
+00:03:32,720 --> 00:03:36,900
+بتبدأ باحمرار، بعدين بازرقاق، بعدين بالاصفرار، بعدين
+
+47
+00:03:37,180 --> 00:03:42,100
+بتروح، هذه كلها بتكون من كميات الـ hemoglobin اللي
+
+48
+00:03:42,100 --> 00:03:46,660
+موجودة في المنطقة، فيه كمان الـ other pigments اللي
+
+49
+00:03:46,660 --> 00:03:53,140
+بتصير عن طريق الـ cosmetics، يعني بيتعرض لتجميل، يعني
+
+50
+00:03:53,140 --> 00:03:56,400
+أشياء تجميلية زي الـ tattoo اللي بنعمل، اللي برسموا
+
+51
+00:03:56,400 --> 00:03:59,940
+فيه الحواجب، أو بيرسموا، بيرسموا فيه على ايديهم الوشم
+
+52
+00:03:59,940 --> 00:04:01,140
+اللي احنا بنسميه
+
+53
+00:04:05,500 --> 00:04:11,540
+في عندنا أمراض بنقدر إحنا نحددها عن طريق النظر
+
+54
+00:04:11,540 --> 00:04:16,480
+للشخص، هذا الجلد ممكن يقولنا إيش نوع المرض اللي
+
+55
+00:04:16,480 --> 00:04:20,460
+هو موجود فيه، أو بيعطينا نوع من الـ diagnosis اللي
+
+56
+00:04:20,460 --> 00:04:24,880
+إحنا على طول بنقدر نعرفها، زي الـ jaundice،
+
+57
+00:04:24,880 --> 00:04:28,420
+الـ cyanosis و الـ erythema، الـ jaundice عبارة عن اصفرار
+
+58
+00:04:28,420 --> 00:04:33,480
+color of the skin and the whites of the eyeballs built
+
+59
+00:04:33,480 --> 00:04:37,320
+up of yellow bilirubin، نتيجة لمشكلة في الـ liver، في
+
+60
+00:04:37,320 --> 00:04:39,900
+عندنا مشكلة بيكون في الكبد، أول ما نشوف واحد
+
+61
+00:04:39,900 --> 00:04:44,300
+بنلاقي هو مصفر أو وجهه أصفر أو أديه أو جلده كله
+
+62
+00:04:44,300 --> 00:04:46,860
+أصفر، بيبقى عامل زي الكركم، لون الكركم أو
+
+63
+00:04:46,860 --> 00:04:51,220
+لون الكمون، بنعرف إنه هذا في عنده مشكلة بنسميها إحنا
+
+64
+00:04:51,220 --> 00:04:55,970
+بالعربي الـ jaundice، الـ cyanosis بنشوف الشخص بنقول له: ما وجهك
+
+65
+00:04:55,970 --> 00:05:00,150
+أزرق؟ بيظهر إنه أنت مش تمام، حاسس فيه إيش؟ عندك
+
+66
+00:05:00,150 --> 00:05:03,110
+اختناق، عندك كذا، أول ما الشخص بيحس بالاختناق أو
+
+67
+00:05:03,110 --> 00:05:05,630
+بيصير فيه عنده مشكلة في عضلة القلب، بيبين عليه الـ
+
+68
+00:05:05,630 --> 00:05:09,530
+cyanosis، أو بيخاف أو بيبرد كتير، يبرد كتير،
+
+69
+00:05:09,530 --> 00:05:12,810
+بيعطيني اللون الـ cyanosis، ليش؟ لأنه بيقل تدفق
+
+70
+00:05:12,810 --> 00:05:15,910
+الدم على المكان و الأكسجين في المكان، فبيعطيني
+
+71
+00:05:15,910 --> 00:05:19,710
+blueish color to the nails and the skin، وطبعا في
+
+72
+00:05:19,710 --> 00:05:22,970
+حاجة اسمها central cyanosis، في حاجة اسمها الـ
+
+73
+00:05:22,970 --> 00:05:25,690
+peripheral cyanosis، الـ central cyanosis
+
+74
+00:05:25,690 --> 00:05:31,150
+بيكون لو كان في القلب، أما الـ peripheral
+
+75
+00:05:31,150 --> 00:05:38,510
+cyanosis فبيصير في الأطراف، اللي فيه ما قلنا هي
+
+76
+00:05:38,510 --> 00:05:41,670
+عبارة عن الـ redness of the skin، عبارة عن the
+
+77
+00:05:41,670 --> 00:05:44,890
+vasodilation أو enlargement of the capillaries in
+
+78
+00:05:44,890 --> 00:05:47,950
+the dermis اللي موجودة في الـ dermis، فبيصير الاحمرار، لو
+
+79
+00:05:47,950 --> 00:05:51,870
+صار فيه inflammation، infection، allergy، to a
+
+80
+00:05:51,870 --> 00:05:57,510
+burn or sun burn، بتعرف إنه الواحد لما يصير عنده حساسية
+
+81
+00:05:57,510 --> 00:06:03,630
+أول مظهر من الحساسية مثلا أكل شيء بتحسس منه زي
+
+82
+00:06:03,630 --> 00:06:08,240
+السمك، زي غيره، ممكن على طول يظهر الحساسية على الوجه
+
+83
+00:06:08,240 --> 00:06:12,960
+وعلى الأيدي وعلى الكتف، بشكل rashes أو احمرار
+
+84
+00:06:12,960 --> 00:06:18,080
+للجلد، أول ما بنحط حقنة فبنلاقي المكان على طول
+
+85
+00:06:18,080 --> 00:06:22,880
+بيصير فيه احمرار، أو إن مثلا صار فيه insect bite،
+
+86
+00:06:22,880 --> 00:06:28,300
+إيش الـ insect bite؟ يعني عضّة حشرات، عضّة حشرات،
+
+87
+00:06:28,300 --> 00:06:32,540
+أول ما بشوفها بنلاقي بقعة حمراء كده صارت في المكان،
+
+88
+00:06:32,540 --> 00:06:36,660
+نتيجة لتدفق الدم عشان تصير عملية الـ inflammation و
+
+89
+00:06:36,660 --> 00:06:40,140
+الـ phagocytosis اللي إحنا اتكلمنا عنها في المحاضرة
+
+90
+00:06:40,140 --> 00:06:45,780
+السابقة، من وظائف الـ skin اللي هي الـ protection و
+
+91
+00:06:45,780 --> 00:06:52,100
+الـ immune، طيب نروح لحاجة اسمها skin glands، الـ skin
+
+92
+00:06:52,100 --> 00:06:59,320
+glands عبارة عن غدد موجودة في الجلد أو تحت الجلد،
+
+93
+00:06:59,320 --> 00:07:05,510
+طيب الغدد هذه زي sebaceous glands، sebum oily
+
+94
+00:07:05,510 --> 00:07:09,950
+substance that keeps hair and skin soft and pliant،
+
+95
+00:07:09,950 --> 00:07:13,970
+يعني هذه الإفرازات تبع الـ gland هذه اللي بتعملها
+
+96
+00:07:13,970 --> 00:07:17,810
+تشحيم، بتزيد للجسم، بتعطينا اللمعان على الجلد، طبعا
+
+97
+00:07:17,810 --> 00:07:23,150
+الجلد لما يكون جاف بتحسّه إنه خشن كده ومش لامع، لكن الـ
+
+98
+00:07:23,150 --> 00:07:26,870
+glands هذه إيش وظيفتها؟ إنها تطلع الـ oils هذه على
+
+99
+00:07:26,870 --> 00:07:29,830
+السطح، لاحظوا إنه إذا الواحد قعد فترة ما غسل شعره
+
+100
+00:07:30,150 --> 00:07:33,650
+بتلاقي بيزيد، ليش بيزيد؟ بتطلع هذه الطبقة، بتضيف لها
+
+101
+00:07:33,650 --> 00:07:41,610
+حماية للبشرة، بتعطي الجسم الإحساس بالنعومة
+
+102
+00:07:41,610 --> 00:07:45,970
+واللمعان، prevent excessive water loss from the skin،
+
+103
+00:07:46,140 --> 00:07:49,400
+إن إحنا قلنا من وظائف الـ skin، الـ skin من وظيفته أصلا إنه
+
+104
+00:07:49,400 --> 00:07:52,860
+يعمل regulation لـ temperature وكمان إنه بده
+
+105
+00:07:52,860 --> 00:07:56,400
+يحافظ على السوائل اللي موجودة في الجسم، فهذه الطبقة
+
+106
+00:07:56,400 --> 00:08:01,780
+الدهنية أو الزيتية اللي موجودة بتمنع خروج السوائل
+
+107
+00:08:01,780 --> 00:08:05,500
+من الجسم، usually usually associated with hair
+
+108
+00:08:05,500 --> 00:08:08,580
+follicles، طبعا هذه بتكون موجودة مع الـ hair، إحنا
+
+109
+00:08:08,580 --> 00:08:12,240
+بنعرف إنه في إحنا لو نتكلم عن الشعر بنقول في عندنا
+
+110
+00:08:12,240 --> 00:08:16,220
+شعر جاف وفي عندنا شعر دهني وفي عندنا شعر عادي، هذا
+
+111
+00:08:16,220 --> 00:08:21,300
+كله بيكون من وين هذه المسميات؟ من كميات الـ oil
+
+112
+00:08:21,300 --> 00:08:25,640
+اللي ممكن تنتجها هذه الغدد، lipid components have
+
+113
+00:08:25,640 --> 00:08:29,780
+antifungal activity، طبعا الدهون اللي موجودة فيها
+
+114
+00:08:29,780 --> 00:08:34,270
+بتعمل مضادة للفطريات، simply branched gland،
+
+115
+00:08:34,270 --> 00:08:40,150
+هذا نوعها وشكلها، found in the dermis except in the
+
+116
+00:08:40,150 --> 00:08:45,210
+palm and the soles، موجودة في كل الـ dermis ما عدا الـ
+
+117
+00:08:45,210 --> 00:08:50,650
+hands و ما عدا الـ soles اللي هي الباطن، اللي هي باطن
+
+118
+00:08:50,650 --> 00:08:55,270
+أسفل القدم، secretions increase in adolescents may
+
+119
+00:08:55,270 --> 00:09:01,850
+lead to formation of pimples and blackheads،
+
+120
+00:09:05,090 --> 00:09:08,410
+أما الـ sweat glands فقلنا هي عبارة عن الـ
+
+121
+00:09:08,410 --> 00:09:13,130
+regulation لـ heat أو الـ temperature، وظيفتها الـ ..
+
+122
+00:09:13,130 --> 00:09:16,290
+إحنا بنقول الـ sweat glands هي المكيف تبع الجسم،
+
+123
+00:09:16,290 --> 00:09:19,250
+إيش يعني المكيف تبع الجسم؟ إذا ارتفعت درجة حرارة
+
+124
+00:09:19,250 --> 00:09:24,810
+الجسم فبتلاقي بيـ .. بيصير فيه تعرق، التعرق هذا
+
+125
+00:09:24,810 --> 00:09:28,880
+بيخفف من حرارة الجسم الداخلية وبيطلع معاه كل
+
+126
+00:09:28,880 --> 00:09:34,520
+المواد السامة، طبعا widespread in the skin، موجودة
+
+127
+00:09:34,520 --> 00:09:38,460
+على كل الجسم، originate in deeper dermis or
+
+128
+00:09:38,460 --> 00:09:42,740
+hypodermis، هي عبارة عن excretory glands و
+
+129
+00:09:42,740 --> 00:09:47,920
+apocrine glands و eccrine glands و mammary
+
+130
+00:09:47,920 --> 00:09:52,760
+glands اللي هي عبارة عن خلايا الحليب، الـ eccrine
+
+131
+00:09:52,760 --> 00:09:56,960
+اللي هي الخلايا الصمغية اللي بتفرز السائل الصمغي
+
+132
+00:09:56,960 --> 00:10:03,090
+اللي موجود في الأذن، والخلايا التعرقية، والتي
+
+133
+00:10:03,090 --> 00:10:11,510
+تفرز الدموع، exocrine glands، numerous sweat
+
+134
+00:10:11,510 --> 00:10:16,130
+glands، بتعطينا هي عبارة عن small glands distributed
+
+135
+00:10:16,130 --> 00:10:21,150
+over the total body surface except for a small
+
+136
+00:10:21,150 --> 00:10:24,490
+small area، يعني ببعض الـ areas بس اللي مش موجودة، لكن
+
+137
+00:10:24,490 --> 00:10:29,670
+هي منتشرة على الجسم كله، simple called tubular، يعني
+
+138
+00:10:29,670 --> 00:10:37,470
+عبارة عن tube، و الـ tube هذه كده ملفوفة مع بعضها،
+
+139
+00:10:37,470 --> 00:10:42,190
+function throughout the life، طبعا كل حياتنا فيه
+
+140
+00:10:42,190 --> 00:10:45,850
+secretions بتطلع عن طريق الـ sweat secrets،
+
+141
+00:10:47,270 --> 00:10:51,690
+respiration or sweat، بيصير عملية اللي هي خروج
+
+142
+00:10:51,690 --> 00:10:55,610
+التعرق، eliminate waste، بتطلع مع العرق هذا كتير من
+
+143
+00:10:55,610 --> 00:10:58,910
+الـ waste products اللي بيفرزها الجسم، and help
+
+144
+00:10:58,910 --> 00:11:01,970
+maintain a constant cool temperature، الحرارة
+
+145
+00:11:01,970 --> 00:11:06,330
+الداخلية تبع الجسم بتنظم عن طريق خروج التعرق هذه،
+
+146
+00:11:06,330 --> 00:11:10,430
+فبتقل الحرارة الداخلية وبتطلع على السطح،
+
+147
+00:11:11,010 --> 00:11:14,710
+apocrine glands موجودة داخل الـ  hair follicle
+
+148
+00:11:14,710 --> 00:11:40,970
+الـ apocrine glands
+
+149
+00:11:43,860 --> 00:11:48,860
+الـ ceruminous glands، modified apocrine sweat
+
+150
+00:11:48,860 --> 00:11:54,360
+glands، طبعا هي شكلها عامل زي الـ sweat glands
+
+151
+00:11:54,360 --> 00:11:59,920
+called و tubular، هي عبارة عن tube و ملفوفة على بعضها،
+
+152
+00:12:01,890 --> 00:12:06,450
+contents into external ear canal، بتعطيني اللي هي
+
+153
+00:12:06,450 --> 00:12:14,870
+الشمع هذا اللي موجود في الأذن، mixed secretions of
+
+154
+00:12:14,870 --> 00:12:20,850
+sebaceous and serous glands، called cerumen، اللي
+
+155
+00:12:20,850 --> 00:12:24,930
+هو الـ wax اللي هو الموجود في الأذن، function to
+
+156
+00:12:24,930 --> 00:12:29,150
+protect area from dehydration، لو صار في عندنا
+
+157
+00:12:29,150 --> 00:12:32,390
+excessive secretion اللي بتعمل blockage للـ ear
+
+158
+00:12:32,390 --> 00:12:39,890
+canal وبيبطل الشخص يقدر يسمع، نروح لحاجة من مكونات الـ
+
+159
+00:12:39,890 --> 00:12:45,070
+appendages تبعت الـ skin، الـ hair، الـ hair موجود على
+
+160
+00:12:45,070 --> 00:12:52,150
+تقريبا على معظم سطح الجسم، over entire body except
+
+161
+00:12:52,150 --> 00:12:58,070
+the palms of the hands and soles of the feet and a
+
+162
+00:12:58,070 --> 00:13:03,710
+few other small areas، fine and soft hair، الـ lanugo
+
+163
+00:13:03,710 --> 00:13:08,010
+present before birth، الـ lanugo اللي هو عبارة
+
+164
+00:13:08,010 --> 00:13:14,830
+عن إيش؟ الزغب اللي بيكون موجود على سطح جلد الطفل،
+
+165
+00:13:14,830 --> 00:13:21,240
+بيكون اللي هي كتير كتير ناعم ورقيق، course pubic and
+
+166
+00:13:21,240 --> 00:13:24,460
+axillary hair اللي موجود في منطقة الـ pubis وتحت
+
+167
+00:13:24,460 --> 00:13:28,340
+الابط اللي بتظهر عند البلوغ، that developed at puberty، called terminal
+
+168
+00:13:28,340 --> 00:13:34,380
+hair، طبعا الـ terminal hair بيكون هو بيظهر بعد فترة
+
+169
+00:13:34,380 --> 00:13:41,530
+البلوغ، طبعا function of the hair، وظيفة الشعر
+
+170
+00:13:41,530 --> 00:13:47,330
+protection، شكل حماية، heat retention، بيحافظ على
+
+171
+00:13:47,330 --> 00:13:51,730
+الاحتفاظ بالحرارة، prevent loss of conducted heat
+
+172
+00:13:51,730 --> 00:13:56,540
+from the scalp to the surrounding air، بيمنع اللي هو
+
+173
+00:13:56,540 --> 00:14:00,280
+تهرب أو هروب الحرارة، بيعطيني facial expression،
+
+174
+00:14:00,280 --> 00:14:05,900
+إحنا بنطلع على الشخص على وجهه، الحواجب، أحيانا حركة
+
+175
+00:14:05,900 --> 00:14:09,020
+الحواجب بتعطيني facial expression، هذا مكشر، هذا
+
+176
+0
+
+223
+00:17:55,440 --> 00:17:59,380
+hormone طبعا الصلع بيصير عند الرجال و نادرا ما
+
+224
+00:17:59,380 --> 00:18:06,330
+يصير فيه عند النساء. الصلع ممكن يكون genetic لأن
+
+225
+00:18:06,330 --> 00:18:12,330
+الأباء ممكن مثلا هذا مثلا شخص من عائلة بصلع فهو
+
+226
+00:18:12,330 --> 00:18:15,430
+بيطلع شعره، وطبعا الصلع بيبدأ في سن مبكرة يعني
+
+227
+00:18:15,430 --> 00:18:19,210
+حوالي سن الخامسة والعشرين بيبدأ علامات الصلع تظهر
+
+228
+00:18:19,210 --> 00:18:25,090
+على الشخص، ويخف الشعر من المناطق الأمامية، وطبعا
+
+229
+00:18:25,090 --> 00:18:30,060
+الهرومونات الدكارية لها تأثير على هذا الشيء. طبعا ال
+
+230
+00:18:30,060 --> 00:18:34,140
+hair thinning and baldness, الalopecia hair
+
+231
+00:18:34,140 --> 00:18:42,430
+thinning يعني بيصير نقص الشعر كتير، ممكن يقل
+
+232
+00:18:42,430 --> 00:18:52,290
+لي يعني صلع، أو ممكن يخف الشعر بصورة كتير ملحوظة.
+
+233
+00:18:52,290 --> 00:18:56,550
+genetically determined and sex-influenced condition.
+
+234
+00:18:56,550 --> 00:19:02,740
+هي اللي بتأثر على الأظافر. حاجة اسمها أظافر، الأظافر
+
+235
+00:19:02,740 --> 00:19:06,000
+جزء من الجلد، طبعا consist of epidermal cells.
+
+236
+00:19:06,000 --> 00:19:09,980
+converted into hard keratin. يعني بتتحول إلى كراتين
+
+237
+00:19:09,980 --> 00:19:13,560
+هذا  له بالمناسبة الشعر كمان لو صار فيه excessive
+
+238
+00:19:13,560 --> 00:19:17,460
+keratin بيصير حاجة اسمها قشرة. موجود القشرة اللي في
+
+239
+00:19:17,460 --> 00:19:20,600
+الشعر، اللي لو حكينا كده شوية بتطلع قشور. فهذا
+
+240
+00:19:20,600 --> 00:19:25,120
+excessive keratin. خلايا ميتة بتطلع على ال... على
+
+241
+00:19:25,120 --> 00:19:29,680
+سطح ال... سطح الجلد، فبتعمل قشور. هذه القشور اللي
+
+242
+00:19:29,680 --> 00:19:36,530
+احنا بنشوفها عن طريق ال... الجلد، لونها أبيض. أما
+
+243
+00:19:36,530 --> 00:19:40,110
+الأظافر فهي consists of epidermic أو epidermal
+
+244
+00:19:40,110 --> 00:19:43,870
+cells converted to hard keratin. الnail visible
+
+245
+00:19:43,870 --> 00:19:48,010
+part of each nail اللي هو واضح بالصورة زي ما احنا
+
+246
+00:19:48,010 --> 00:19:52,970
+شايفينها. ال root، اللي لها roots. Part of the nail
+
+247
+00:19:52,970 --> 00:19:58,950
+in a groove, hardened by a fold of the skin. اللي
+
+248
+00:20:00,010 --> 00:20:04,310
+اللي عندنا زي نصف القمر هذا، أو الmoon shape white
+
+249
+00:20:04,310 --> 00:20:08,490
+area. نيارستا روت هنا احنا شايفينها. يعني في عندنا
+
+250
+00:20:08,490 --> 00:20:14,650
+nail root زيها، وفي عندنا ال lunula، وفي عندنا ال
+
+251
+00:20:14,650 --> 00:20:17,750
+nail body، وفي عندنا ال free ending هذا اللي احنا
+
+252
+00:20:17,750 --> 00:20:22,350
+بنقصّها. طبعا ما فيش إحساس بال nails. A nail bed
+
+253
+00:20:22,350 --> 00:20:26,170
+layer of epithelium under nail body contains
+
+254
+00:20:26,170 --> 00:20:29,250
+abundant blood vessels. في كتير من ال blood vessels
+
+255
+00:20:29,540 --> 00:20:38,460
+موجودة في هذا المكان. appeared pink. موجودة
+
+256
+00:20:38,460 --> 00:20:43,360
+في هذا المكان. appeared pink. موجودة في هذا المكان.
+
+257
+00:20:43,360 --> 00:20:43,740
+appeared pink. موجودة في هذا المكان. appeared pink
+
+258
+00:20:43,740 --> 00:20:43,760
+موجودة في هذا المكان. appeared pink. موجودة في هذا
+
+259
+00:20:43,760 --> 00:20:44,440
+appeared pink. موجودة في هذا المكان. appeared pink
+
+260
+00:20:44,440 --> 00:20:45,820
+موجودة في هذا المكان. appeared pink. موجودة في هذا
+
+261
+00:20:45,820 --> 00:20:48,160
+المكان. appeared pink. موجودة في هذا المكان. appeared
+
+262
+00:20:48,160 --> 00:20:52,990
+pink. موجودة في هذا المكان. appeared pink. موجودة. نال
+
+263
+00:20:52,990 --> 00:20:57,910
+اكثار النال بمتوسط. بيصير فيه تكاثر of the cells of
+
+264
+00:20:57,910 --> 00:21:06,210
+stratum granulosum beneath the lunula. Average
+
+265
+00:21:06,210 --> 00:21:10,850
+growth of point five-and-a-half millimeters a week.
+
+266
+00:21:10,850 --> 00:21:15,430
+Slightly over one inch per year. طبعا احنا بنعرف
+
+267
+00:21:15,430 --> 00:21:19,870
+أن في ناس عندنا بيربوا أظافرهم، فممكن تطول هذه
+
+268
+00:21:19,870 --> 00:21:24,450
+الأظافر، وهي أصلا مش من السنة أن احنا نربوها يعني
+
+269
+00:21:24,450 --> 00:21:29,780
+تقليم الأظافر من السنة المحببة. نروح لل burn، الburn
+
+270
+00:21:29,780 --> 00:21:34,040
+عبارة عن إيش؟ حرق بيصير على سطح الجلد، يعني أول شيء
+
+271
+00:21:34,040 --> 00:21:39,680
+بيتعرض للحرق هو الجلد. Tissue damage of excessive
+
+272
+00:21:39,680 --> 00:21:47,140
+heat أو electricity أو radioactivity أو corrosive
+
+273
+00:21:47,140 --> 00:21:53,400
+chemicals that destroy their denatured proteins in
+
+274
+00:21:53,400 --> 00:21:58,410
+the exposed cells. هي called burn. أي شيء يعرض
+
+275
+00:21:58,410 --> 00:22:02,450
+الجلد لعملية الاحتراق فهي احنا بنسميها burn.
+
+276
+00:22:02,450 --> 00:22:06,570
+Generally the systemic effects of burns are greater
+
+277
+00:22:06,570 --> 00:22:12,090
+threat to life than the local effects. طيب يعني
+
+278
+00:22:12,090 --> 00:22:16,230
+ال systemic بشكل خطر ليش؟ ال systemic بشكل خطر
+
+279
+00:22:16,230 --> 00:22:20,970
+لأنه ممكن أن يؤدي لفقدان
+
+280
+00:22:20,970 --> 00:22:26,510
+للسوائل. يبقى seriousness of burn is determined
+
+281
+00:22:26,510 --> 00:22:30,210
+by its depth، و ال extent، و ال area involved، و ال
+
+282
+00:22:30,210 --> 00:22:33,990
+burn zone is، and general health. هذه كلها عوامل
+
+283
+00:22:33,990 --> 00:22:37,690
+بتقول أن إذا كان هذا الشخص، ممكن أن إذا انحرق ينجو أو
+
+284
+00:22:37,690 --> 00:22:42,090
+لا ينجو، سواء كان إذا كان الحرق عميق، إذا كان واسع
+
+285
+00:22:42,090 --> 00:22:47,150
+ماخذ area كبيرة من الجسم، و عمر المريض، و ال
+
+286
+00:22:47,150 --> 00:22:51,890
+general health طبيعته قبل الحرق. و in the burn area
+
+287
+00:22:51,890 --> 00:22:55,990
+exceeds 70%, over half of the victims die. يعني إذا
+
+288
+00:22:55,990 --> 00:23:01,210
+كان في حرق نسبته على الجسم أكثر من 70% فهذا المريض
+
+289
+00:23:01,210 --> 00:23:05,890
+أو هذا الشخص اللي اتعرض لحرق ممكن أن يتوفى.
+
+290
+00:23:06,230 --> 00:23:10,330
+Destruction of a protein of the skin نتيجة
+
+291
+00:23:10,330 --> 00:23:14,990
+chemical أو electricity أو heat. اللي بيصير ممكن
+
+292
+00:23:14,990 --> 00:23:18,470
+يصير shock due to water, plasma, and plasma protein
+
+293
+00:23:18,470 --> 00:23:22,210
+loss. ممكن يدخل المريض في shock، ممكن يصير عنده
+
+294
+00:23:22,210 --> 00:23:25,450
+مشاكل في ال circulation، أو في ال kidney problems
+
+295
+00:23:25,450 --> 00:23:29,430
+نتيجة ال plasma loss. وممكن يصير طبعا الجلد لأنه
+
+296
+00:23:29,430 --> 00:23:34,030
+قلنا هو خط الحماية تبع الجسم من البكتيريا، فبالتالي
+
+297
+00:23:34,030 --> 00:23:39,630
+لو صار للشخص حرق، هذا يتأثر، فبيصير قابل لل
+
+298
+00:23:39,630 --> 00:23:45,030
+infection، وبيؤدي طبعا لمشاكل كتير كتير. طبعا ال
+
+299
+00:23:45,030 --> 00:23:49,050
+types. في عندنا ال first degree، بس ال epidermis زي
+
+300
+00:23:49,050 --> 00:23:51,850
+اللي بيصير من الشمس لما بيروح على البحر، احنا بس
+
+301
+00:23:51,850 --> 00:23:55,390
+ال epidermis اللي بتأثر. First degree burn أو sun
+
+302
+00:23:55,390 --> 00:23:57,270
+burn.
+
+303
+00:23:58,660 --> 00:24:02,600
+ال second degree destroy entire epidermis، كل ال
+
+304
+00:24:02,600 --> 00:24:05,000
+epidermis and part of dermis، يبقى ال thickness
+
+305
+00:24:05,000 --> 00:24:10,360
+تبعه أكثر، fluid fills blisters، بيظهر الفقعات على
+
+306
+00:24:10,360 --> 00:24:17,540
+الجسم، على الجلد، dermis are not damaged، ال
+
+307
+00:24:17,540 --> 00:24:20,920
+epidermal derivatives، derivatives are not damaged،
+
+308
+00:24:20,920 --> 00:24:25,790
+heals without grafting، يعني ما بيحتاج أن نعمله
+
+309
+00:24:25,790 --> 00:24:31,010
+skin graft، أو عملية. بياخد من ثلاثة لأربعة weeks، and
+
+310
+00:24:31,010 --> 00:24:37,050
+ممكن يؤثر ويصير في عندي scar. إيش يعني scar؟ ندبة
+
+311
+00:24:37,050 --> 00:24:41,950
+بتصير موجودة على ال... ال... أما ال third degree
+
+312
+00:24:41,950 --> 00:24:46,330
+هذا بنسميه احنا full thickness. أخذ ال dermis و ال
+
+313
+00:24:46,330 --> 00:24:51,040
+epidermis و كل ال epidermal derivatives. Damage area
+
+314
+00:24:51,040 --> 00:24:58,740
+is not due to loss of sensory nerves. لأنه أخذ كل
+
+315
+00:24:58,740 --> 00:25:01,840
+ال dermis. فال dermis هو موجود فيه كل ال receptors
+
+316
+00:25:01,840 --> 00:25:04,540
+اللي موجودة على ال skin، أو ال nervous receptors، أو
+
+317
+00:25:04,540 --> 00:25:11,860
+ال sensory receptors. وهذا بيكون الألم فيه أقل طبعا.
+
+318
+00:25:11,860 --> 00:25:16,540
+ال rules of 9s. هذه راح ندرسها بالتفصيل لما نتكلم عن
+
+319
+00:25:16,540 --> 00:25:22,970
+موضوع الحروق. كيف بتقسم الجسم لتسعة في المئة، تسعة في
+
+320
+00:25:22,970 --> 00:25:28,370
+المئة، وبتقسم مثلا lower limb بتاخد تسعة في المئة،
+
+321
+00:25:28,370 --> 00:25:32,910
+تسعة في المئة، إثنتين مع بعض، إثنتين. أما ال upper
+
+322
+00:25:32,910 --> 00:25:36,830
+limb بتاخد أربعة ونصف، وأربعة ونصف، إثنتين يعني تسعة
+
+323
+00:25:36,830 --> 00:25:43,120
+في. The rules of 9s هذه of 9s بتحدد لنا نسبة انتشار
+
+324
+00:25:43,120 --> 00:25:47,700
+الحرق على الجسم، اللي قلنا هي ممكن تؤدي لو كانت
+
+325
+00:25:47,700 --> 00:25:53,920
+أكثر من 70%، الانتشار، فممكن تؤدي إلى الوفاة. فبياخد
+
+326
+00:25:53,920 --> 00:25:58,760
+ال face أربعة ونصف، أما ال back of the skull بياخد
+
+327
+00:25:58,760 --> 00:26:04,070
+أربعة ونصف. منطقة ال trunk بتاخد تقريبا ستة وثلاثين
+
+328
+00:26:04,070 --> 00:26:08,890
+في المئة. وال lower و ال upper limbs، و ال anterior
+
+329
+00:26:08,890 --> 00:26:14,910
+أو ال posterior. ففي نهاية المحصلة بتكون أنها مئة
+
+330
+00:26:14,910 --> 00:26:20,180
+بالمئة. طبعا ال cycle of life of the skin في ال
+
+331
+00:26:20,180 --> 00:26:23,660
+children بيكون عندنا smooth, unlined, characterized
+
+332
+00:26:23,660 --> 00:26:27,620
+by elasticity and flexibility. طبعا عندنا ال skin
+
+333
+00:26:27,620 --> 00:26:36,300
+في سن الأطفال بيكون كثير  skin ضعيف وناعم.
+
+334
+00:26:36,300 --> 00:26:39,580
+بيقولوا يعني بيقولوا أن بشرتهم زي الأطفال ليش؟
+
+335
+00:26:39,580 --> 00:26:42,560
+بشرتهم زي الأطفال لأنها ناعمة كتير، فيها كتير من ال
+
+336
+00:26:42,560 --> 00:26:47,910
+... مش دودة، ما بيكونش فيها تجعيد ولا فيها ثنيات،
+
+337
+00:26:47,910 --> 00:26:52,270
+characterized by elasticity and flexibility، أقل
+
+338
+00:26:52,270 --> 00:26:55,950
+تعَرُّق، وفي عندنا rapid healing. يعني الطفل لما بنقصّ
+
+339
+00:26:55,950 --> 00:26:59,930
+بإصبعه فيه من يوم ما بنولد إلا ما نجرحه، لكن بلحظة
+
+340
+00:26:59,930 --> 00:27:04,220
+اللحظات. يعني ما بيعدي يوم إلا بيكون صار فيه healing.
+
+341
+00:27:04,220 --> 00:27:08,260
+وأي جرح بتتعرض له الأطفال طبعا أسهل كتير أنه
+
+342
+00:27:08,260 --> 00:27:13,160
+يلتئم من الأكبر. أما ال adult ف development and
+
+343
+00:27:13,160 --> 00:27:16,840
+activation of sebaceous and sweat glands بتزيد،
+
+344
+00:27:16,840 --> 00:27:20,180
+increase the sweat production، بيصير للجسم طبعا
+
+345
+00:27:20,180 --> 00:27:22,980
+هيبقى على الأطفال، فشيلهم ريحة عرق طبعا، أما
+
+346
+00:27:22,980 --> 00:27:26,020
+الأكبر بس تقريبا جامعتهم بتشعروا بريحة العرق طبعا
+
+347
+00:27:26,020 --> 00:27:29,550
+بعد يوم طويل أو يوم قصير أو في أجواء حارة زي اللي
+
+348
+00:27:29,550 --> 00:27:32,290
+احنا عايشينها أحيانا. بيصير increase ل sebum
+
+349
+00:27:32,290 --> 00:27:35,530
+production. فبيصير حاجة اسمها أكنية احنا بنسميه
+
+350
+00:27:35,530 --> 00:27:38,630
+حب الشباب. حب الشباب هذا اللي بيظهر في سن
+
+351
+00:27:38,630 --> 00:27:43,450
+ال adolescents. أما الناس ال elderly دول اللي
+
+352
+00:27:43,450 --> 00:27:47,270
+بيبين يعني أنت الشخص بتعرف قد ايش عمره أحيانا من شكل
+
+353
+00:27:47,270 --> 00:27:55,080
+ال skin عنده. طبعا بيبدأ التقدم بالعمر بإبطاء ال
+
+354
+00:27:55,080 --> 00:27:59,860
+repair لل skin. بيصير عملية ال granulation، عملية
+
+355
+00:27:59,860 --> 00:28:05,620
+تجديد ال skin هذه بتصير أقل. يبقى skin repair
+
+356
+00:28:05,620 --> 00:28:08,960
+process takes longer due to reduced number and
+
+357
+00:28:08,960 --> 00:28:12,880
+activity of skin cells. يعني ال skin بيصير فيه
+
+358
+00:28:12,880 --> 00:28:16,120
+wrinkles. نطلع على الشخص نلاقي في وجهه تجعيد، في
+
+359
+00:28:16,120 --> 00:28:21,920
+جسمه تجعيد. الجسم بيرهل كمان، بيصير less elastic
+
+360
+00:28:21,920 --> 00:28:26,600
+أو less resilient. ال skin alone طبعا response is
+
+361
+00:28:26,600 --> 00:28:29,500
+diminished. بيصير الجرح، ممكن احنا بنشوف حتى الناس
+
+362
+00:28:29,500 --> 00:28:32,960
+اللي عندهم أمراض، أول ما بيصابوا بيصير في عندهم جرح
+
+363
+00:28:32,960 --> 00:28:37,040
+بيصير صعب الالتئام وكبير. بالسرعة طبعا، جرحه بيلتئم
+
+364
+00:28:37,280 --> 00:28:42,420
+أقل أو بياخد وقت أطول من الصغير. Become drier due
+
+365
+00:28:42,420 --> 00:28:45,940
+to decreased sebaceous gland activity. فيبدأ الجسم
+
+366
+00:28:45,940 --> 00:28:49,560
+الجفاف. عشان هيك الجسم كبار السن بيحتاج الكثير من
+
+367
+00:28:49,560 --> 00:28:54,620
+الترطيب. Altered skin and hair pigmentation. بشوف
+
+368
+00:28:54,620 --> 00:28:59,100
+البقع السوداء المنتشرة أو البنية المنتشرة على جلد
+
+369
+00:28:59,100 --> 00:29:08,320
+كبار السن. طبعا بيقلل ال sweating، بيقلل التعرق، ال
+
+370
+00:29:08,320 --> 00:29:12,320
+blood supply على ال dermis بتقل، ال hair بيصير
+
+371
+00:29:12,320 --> 00:29:18,460
+أضعف، و... و كمان بيشيب. The production of vitamin D
+
+372
+00:29:18,460 --> 00:29:24,440
+برضه بيقل. بيصير في عندنا ال skin cancer. و هذه بعض
+
+373
+00:29:24,440 --> 00:29:31,140
+المظاهر. لـ...  شايفين شكل ال skin في كبار السن طبعا
+
+374
+00:29:31,140 --> 00:29:36,560
+مختلف تماما عن ما كنا نشوف في الصور. في عندنا
+
+375
+00:29:36,560 --> 00:29:40,600
+drying لل epidermis. في عندنا thinning لل epidermis.
+
+376
+00:29:40,600 --> 00:29:45,460
+في عندنا reducing لل sweat glands. في عندنا ال
+
+377
+00:29:45,460 --> 00:29:49,120
+thinning dermis، reducing the blood supply.
+
+378
+00:29:49,120 --> 00:29:52,900
+بتصير كلها attenuated. في change in the distribution
+
+379
+00:29:52,900 --> 00:29:58,820
+of the fat and hair. في عندنا a fewer activity
+
+380
+00:29:58,820 --> 00:30:05,360
+follicles. وفي عندنا melanocytes بتصير pale. ال
+
+381
+00:30:05,360 --> 00:30:10,380
+skin بتصير عادة عندهاش قدرة على تحمل ال sunlight.
+
+382
+00:30:11,070 --> 00:30:15,110
+وبهذا احنا بنكون خلصنا من ال Integumentary System.
+
+383
+00:30:15,110 --> 00:30:19,230
+ويعطيكم العافية ونراكم في الأسبوع القادم إن شاء
+
+384
+00:30:19,230 --> 00:30:19,450
+الله
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..9cd54515a3802085e002648faf3a3467861d5d67
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg_postprocess.srt
@@ -0,0 +1,1536 @@
+1
+00:00:04,910 --> 00:00:08,090
+بسم الله الرحمن الرحيم اليوم بدنا نكمل الموضوع ال
+
+2
+00:00:08,090 --> 00:00:12,910
+skin أو الـ Integumentary System و شرحنا في
+
+3
+00:00:12,910 --> 00:00:16,850
+المحاضرة السابقة طبقات ال skin ال epidermis و
+
+4
+00:00:16,850 --> 00:00:23,250
+dermis و subcutaneous tissue و قلنا أن ال skin هو
+
+5
+00:00:23,250 --> 00:00:28,090
+اللي بيحدد ال colorال color of the body طبعا بتحدد
+
+6
+00:00:28,090 --> 00:00:33,230
+عن طريق ال pigmentation أو ال amount of melanin،
+
+7
+00:00:33,230 --> 00:00:37,570
+في عندنا أكتر من عامل بيحدد لون ال skin، في عندنا
+
+8
+00:00:37,570 --> 00:00:40,830
+genetic factors، في عندنا environmental factors،
+
+9
+00:00:40,830 --> 00:00:43,090
+في عندنا physiological factors
+
+10
+00:00:44,950 --> 00:00:49,930
+عبارة عن ال .. لو تكلمنا عن ال everything مثلا صار
+
+11
+00:00:49,930 --> 00:00:55,650
+في عندنا إحمرار في ال .. في الجسم، معناه إنه صار
+
+12
+00:00:55,650 --> 00:00:59,530
+فيه تركيز لل flood في المنطقة، بنسميها حاجة اسمها
+
+13
+00:00:59,530 --> 00:01:03,130
+بعضه dilatation، ممكن تصير بعضه constriction،
+
+14
+00:01:03,130 --> 00:01:07,920
+بتسكرالأوعية الدموية في عندنا accumulation of
+
+15
+00:01:07,920 --> 00:01:11,240
+carotene أو joindes بيصير في عندنا مشكلة مثلا في
+
+16
+00:01:11,240 --> 00:01:16,300
+ال .. في الكبت أو تركيز ل .. او بيصير اسفرار اللي
+
+17
+00:01:16,300 --> 00:01:22,450
+بيسميه joindes اللي هو الريان مثلا بيزيدبيخللون ال
+
+18
+00:01:22,450 --> 00:01:27,730
+skin أصفر أو العين بياض البنت العين بيصير أصفر في
+
+19
+00:01:27,730 --> 00:01:30,590
+عندنا genetic factors ليش بنقول في ناس بيض في ناس
+
+20
+00:01:30,590 --> 00:01:36,510
+سمر في حدا هذا لونه أسود في ناس لونهم قمحي هذا
+
+21
+00:01:36,510 --> 00:01:41,110
+بيصير أنه الاتنين مثلا الأب والأم بيض فهذا أبنائهم
+
+22
+00:01:41,110 --> 00:01:44,910
+بيطلعوا بيض الأب والأم سمر أبنائهم بيطلعوا سمر
+
+23
+00:01:44,910 --> 00:01:49,820
+وهكذا يبقى في عندناالـ Genetic Factors Varying
+
+24
+00:01:49,820 --> 00:01:52,980
+Amounts of Melanin Varying Size of Melanin
+
+25
+00:01:52,980 --> 00:01:57,960
+Granules أما الـ Environmental Factors فالتعرض للـ
+
+26
+00:01:57,960 --> 00:02:01,660
+Sunlight و الـ Ultraviolet و الـ X-Ray بيعطينا
+
+27
+00:02:01,660 --> 00:02:06,640
+Darkness للملامين بيصير حاجة اسمها Pigmentation of
+
+28
+00:02:06,640 --> 00:02:13,640
+Melanin أما بالنسبة لتحديد
+
+29
+00:02:13,640 --> 00:02:18,100
+اللونعن طريق الميلانين يبقى الـ Basic determinants
+
+30
+00:02:18,100 --> 00:02:23,720
+of skin color عبارة عن الـ quality، الـ quantity
+
+31
+00:02:23,720 --> 00:02:27,520
+of الميلانين الـ type and distribution of ميلانين
+
+32
+00:02:27,520 --> 00:02:31,680
+حدد لللون الـ beta-carotene عبارة عن جروب فياليش
+
+33
+00:02:31,680 --> 00:02:35,820
+pigmentation from the food also contribute in skin
+
+34
+00:02:35,820 --> 00:02:44,480
+color ممكن يتأثر على لون الجل الـ hemoglobinعبارة
+
+35
+00:02:44,480 --> 00:02:49,580
+عن ال .. ال redness اللي بيجي على ال skin أو اللي
+
+36
+00:02:49,580 --> 00:02:52,440
+بيبين على ال skin ال redder .. ال redder skin
+
+37
+00:02:52,440 --> 00:02:56,920
+color when blood flow to the skin increases ممكن
+
+38
+00:02:56,920 --> 00:03:01,500
+صار في عندي تدفق للدم في منطقة معينة فبتصير هذه
+
+39
+00:03:01,500 --> 00:03:06,220
+المنطقة لونها أحمر لو صار الدم إجا على المنطقة
+
+40
+00:03:06,220 --> 00:03:10,220
+اللي كان فيش فيه oxygen فبصير لونها أزرق أو جاي
+
+41
+00:03:10,220 --> 00:03:17,020
+على لون بنفس الجيبلو كان في عندنا ضربات او كذا في
+
+42
+00:03:17,020 --> 00:03:21,540
+الجسم فبنلاقي ان بتيجي حاجة زي ال rainbow او قز
+
+43
+00:03:21,540 --> 00:03:25,860
+قوس قزح على الجسم تطلع انه احنا بنخبط في المكان و
+
+44
+00:03:25,860 --> 00:03:29,180
+بناخدش بالنا من الخط اللي كان بعدها فما بنطلع ممكن
+
+45
+00:03:29,180 --> 00:03:32,720
+نلاقي صار في عندي زي ألوان الطيف موجودة على الجسم
+
+46
+00:03:32,720 --> 00:03:36,900
+تبدأ بالإحمرار بعدين بالإزرقاق بعدين بالصفار بعدين
+
+47
+00:03:37,180 --> 00:03:42,100
+بتروح فهذه كلها بتكون من كميات ال hemoglobin اللي
+
+48
+00:03:42,100 --> 00:03:46,660
+موجودة في المنطقة فيه كمان ال other pigments اللي
+
+49
+00:03:46,660 --> 00:03:53,140
+بتسير ع طريق ال cosmetics يعني بيتعرض لتجميل يعني
+
+50
+00:03:53,140 --> 00:03:56,400
+أشياء تجميلية زي ال tattoo اللي بنعمل اللي برسموا
+
+51
+00:03:56,400 --> 00:03:59,940
+فيه الحواجب أو بيرسموا بيرسموا فيه على أديهم الوشم
+
+52
+00:03:59,940 --> 00:04:01,140
+اللي احنا بنسميه
+
+53
+00:04:05,500 --> 00:04:11,540
+في عندنا أمراض بنقدر إحنا نحددها عن طريق النظر
+
+54
+00:04:11,540 --> 00:04:16,480
+للشخص هذا الانجلدوم ممكن يقولنا إيش نوع المرض اللي
+
+55
+00:04:16,480 --> 00:04:20,460
+هو موجود فيه أو بيعطينا نوع من ال diagnosis اللي
+
+56
+00:04:20,460 --> 00:04:24,880
+أنا على طول بقدر أعرفها زي ال joinedness،
+
+57
+00:04:24,880 --> 00:04:28,420
+الcyanosis والاروثيمة ال joinedness عبارة عن يلوش
+
+58
+00:04:28,420 --> 00:04:33,480
+color of the skinand the whites of the ball built
+
+59
+00:04:33,480 --> 00:04:37,320
+up of yellow bilirubin نتيجة لمشكلة في ال liver في
+
+60
+00:04:37,320 --> 00:04:39,900
+عندنا مشكلة بيكون في الكبد أول ما نطلعت واحد
+
+61
+00:04:39,900 --> 00:04:44,300
+بنلاقي هو مصفر أو أو وجهه أصفر أو اديس أو جلده كله
+
+62
+00:04:44,300 --> 00:04:46,860
+أصفر بيبقى هيك عامل زي الكوركوم لون الكوركوم أو
+
+63
+00:04:46,860 --> 00:04:51,220
+لون الكمون بنعرف أنه هذا في عنده مشكلة نسميها احنا
+
+64
+00:04:51,220 --> 00:04:55,970
+بالعرب الالـ cyanosis بنشوف الشخص بنقوله ما الوجهك
+
+65
+00:04:55,970 --> 00:05:00,150
+أزرق يظهر أنه أنت مش ماكل حاسس فيه إيش، عندك
+
+66
+00:05:00,150 --> 00:05:03,110
+اختناق، عندك كذا أول ما الشخص بيحس بالاختناق أو
+
+67
+00:05:03,110 --> 00:05:05,630
+بيصير فيه عنده مشكلة في عضة القلب بيبين عليه ال
+
+68
+00:05:05,630 --> 00:05:09,530
+cyanosis أو بيخاف أو بيبرد كتير، البربل كتير،
+
+69
+00:05:09,530 --> 00:05:12,810
+بيعطيني اللون ال cyanosis، ليش؟ لأنه بيسبقل تدفق
+
+70
+00:05:12,810 --> 00:05:15,910
+الدم على المكان و الأكسجين في المكان، فبيعطيني
+
+71
+00:05:15,910 --> 00:05:19,710
+blueish color to the nails and the skin وطبعا في
+
+72
+00:05:19,710 --> 00:05:22,970
+حاجة اسمها central cyanosis، في حاجة اسمهاالـ
+
+73
+00:05:22,970 --> 00:05:25,690
+peripheral cyanosis الـ central fear of cyanosis
+
+74
+00:05:25,690 --> 00:05:31,150
+بيكون لو كان اللبس بالتنك أما ال peripheral
+
+75
+00:05:31,150 --> 00:05:38,510
+cyanosis فبصير في الأضراب اللي فيه ما قلنا هي
+
+76
+00:05:38,510 --> 00:05:41,670
+عبارة عن ال redness of the skin عبارة عن the
+
+77
+00:05:41,670 --> 00:05:44,890
+vasodilation أو enlargement of the capillaries in
+
+78
+00:05:44,890 --> 00:05:47,950
+the dermis اللي موجودة في الدرمس فبصير الحمراءلو
+
+79
+00:05:47,950 --> 00:05:51,870
+صار فيه انه inflammation, infection, allergy, to
+
+80
+00:05:51,870 --> 00:05:57,510
+burn or burn بتعرف انه الواحد لما صير عنده حساسية
+
+81
+00:05:57,510 --> 00:06:03,630
+أول مظهر من الحساسية مثلا أكل إشي بتحسس منه زي
+
+82
+00:06:03,630 --> 00:06:08,240
+السمك زي غيرهفممكن على طول يظهر الحساسية على الوجه
+
+83
+00:06:08,240 --> 00:06:12,960
+وعلى الأدين وعلى الكتاف بشكل rashes او احمرار
+
+84
+00:06:12,960 --> 00:06:18,080
+لالجلد اول ما بننجر حقنا فبنلاقي المكان على طول
+
+85
+00:06:18,080 --> 00:06:22,880
+بيصير في عنا حمارأو ان مثلا صار فيه insect bite
+
+86
+00:06:22,880 --> 00:06:28,300
+ايش ال insect bite يعني عضت الحشرات عضت الحشرات
+
+87
+00:06:28,300 --> 00:06:32,540
+أول ما بشوفها بنلاقي بقعة حمراء كده صارت في المكان
+
+88
+00:06:32,540 --> 00:06:36,660
+نتيجة لتدفق الدم عشان تصير عملية ال inflammation و
+
+89
+00:06:36,660 --> 00:06:40,140
+ال phagocytosis اللي احنا اتكلمنا عنها في المحادرة
+
+90
+00:06:40,140 --> 00:06:45,780
+السابقة من وظائف ال skin اللي هي ال protection و
+
+91
+00:06:45,780 --> 00:06:52,100
+ال immuneطيب نروح لحاجة اسمها skin glands ال skin
+
+92
+00:06:52,100 --> 00:06:59,320
+glands عبارة عن غداد موجودة في الجلد أو تحت الجلد
+
+93
+00:06:59,320 --> 00:07:05,510
+طيب الغداد ها دى زى sebaceous glandssebum oily
+
+94
+00:07:05,510 --> 00:07:09,950
+substance that keeps hair and skin soft and pliant
+
+95
+00:07:09,950 --> 00:07:13,970
+يعني هذه الإفرازات تبع ال gland هذه اللي بتعملها
+
+96
+00:07:13,970 --> 00:07:17,810
+تشحيم وتزيد لجسم بتعطينا اللمع على الجلد طبعا
+
+97
+00:07:17,810 --> 00:07:23,150
+الجلد لما يكون جاف بتحسه انه خشن كده ومأشر لكن ال
+
+98
+00:07:23,150 --> 00:07:26,870
+glands هذه ايش وظيفتها انها تطلع ال oils هذه على
+
+99
+00:07:26,870 --> 00:07:29,830
+السطح لاحظوا انه اذا الواحد قعد فترة ما حمم الشعر
+
+100
+00:07:30,150 --> 00:07:33,650
+بتلاقي بيزيد، ليش بيزيد؟ بتطلع هذه الطبقة واضفتها
+
+101
+00:07:33,650 --> 00:07:41,610
+حماية البشرة، بتعطي الجسم الإحساس بالنعومة
+
+102
+00:07:41,610 --> 00:07:45,970
+واللمعان، prevent excessive water use of testicles
+
+103
+00:07:46,140 --> 00:07:49,400
+ان احنا قولنا من ال skin ال skin من وظيفه اصلا انه
+
+104
+00:07:49,400 --> 00:07:52,860
+يعمل regulation ل ال temperature و كمان انه بده
+
+105
+00:07:52,860 --> 00:07:56,400
+يحافظ على السوائل اللي موجودة في الجسم فهذه الطبقة
+
+106
+00:07:56,400 --> 00:08:01,780
+الدهنية او الزيتية اللي موجودة بتمنع خروج السوائل
+
+107
+00:08:01,780 --> 00:08:05,500
+من الاسم usually usually associated with hair
+
+108
+00:08:05,500 --> 00:08:08,580
+follicles طبعا هذه بتكون موجودة مع ال hair احنا
+
+109
+00:08:08,580 --> 00:08:12,240
+بنعرف انه في احنا لو نتكلم عن الشعر بنقول في عندنا
+
+110
+00:08:12,240 --> 00:08:16,220
+شعر جاف و في عندنا شعردهوني وفي عنا شعير عادي، هذا
+
+111
+00:08:16,220 --> 00:08:21,300
+كله بيكون من وين هذه المسميات؟ من كميات ال oil
+
+112
+00:08:21,300 --> 00:08:25,640
+اللي ممكن تنتجها هذه لغلط، lipid components have
+
+113
+00:08:25,640 --> 00:08:29,780
+antifungal activity، طبعا الدهون اللي موجودة فيها
+
+114
+00:08:29,780 --> 00:08:34,270
+بتعمل مضادة للفطريات، simply branchesbranch gland
+
+115
+00:08:34,270 --> 00:08:40,150
+هدى نوعها وشكلها found in the dermis except in the
+
+116
+00:08:40,150 --> 00:08:45,210
+palm and the soles موجودة فى كل ال dermis مع ده ال
+
+117
+00:08:45,210 --> 00:08:50,650
+hands و مع ده ال soul اللى هى الباطن اللى يدوى
+
+118
+00:08:50,650 --> 00:08:55,270
+أسفل القدم secretions increase in adolescents may
+
+119
+00:08:55,270 --> 00:09:01,850
+lead to formation of pimples and blackheads
+
+120
+00:09:05,090 --> 00:09:08,410
+أما الـ sweating gland فقلنا هي عبارة عن ال
+
+121
+00:09:08,410 --> 00:09:13,130
+regulation ل ال heat أو ال temperature وزيفة ال ..
+
+122
+00:09:13,130 --> 00:09:16,290
+احنا بنقول ال sweating gland هي المكيف تبع الجسم،
+
+123
+00:09:16,290 --> 00:09:19,250
+ايش يعني المكيف تبع الجسم؟ اذا ارتفعت درجة حرارة
+
+124
+00:09:19,250 --> 00:09:24,810
+الجسم فبتلاقي بي .. بيصير فيه تعرق، التعرق هذا
+
+125
+00:09:24,810 --> 00:09:28,880
+بيخفف من حرارة الجسم الداخلية و بيطلع معاهكل
+
+126
+00:09:28,880 --> 00:09:34,520
+المواد السامة طبعا widespread in the skin موجودة
+
+127
+00:09:34,520 --> 00:09:38,460
+على كل الجسم originate in deeper dermis or
+
+128
+00:09:38,460 --> 00:09:42,740
+hypodermis هي عبارة عن execrating gland و
+
+129
+00:09:42,740 --> 00:09:47,920
+أبوكرايني gland و siri siri monas gland و ممرري
+
+130
+00:09:47,920 --> 00:09:52,760
+gland اللي هي عبارة عن خلايا الحليب ال siri monas
+
+131
+00:09:52,760 --> 00:09:56,960
+اللي هي الخلايا الصمغية اللي بتفرز السائل الصمغي
+
+132
+00:09:56,960 --> 00:10:03,090
+اللي موجودفي الأذن والخلايا التعرق العراقية والتي
+
+133
+00:10:03,090 --> 00:10:11,510
+تفرز الدموع اكسوكراين اجلانز مست نمورا سويتنج
+
+134
+00:10:11,510 --> 00:10:16,130
+اجلانز بتعطينا هي عبارة small glands distributed
+
+135
+00:10:16,130 --> 00:10:21,150
+over the total body surfaceexception of a small
+
+136
+00:10:21,150 --> 00:10:24,490
+small area يعني ببعض ال area بس اللي مش موجودة لكن
+
+137
+00:10:24,490 --> 00:10:29,670
+هي منتشرة على الجسم كله symbol called tubular يعني
+
+138
+00:10:29,670 --> 00:10:37,470
+عبارة عن tube و ال tube ها دي كده ملوية مع بعضها
+
+139
+00:10:37,470 --> 00:10:42,190
+function throughout the life طبعا كل حياتنا فيه
+
+140
+00:10:42,190 --> 00:10:45,850
+secretions بتطلع عن طريق ال sweet secrets
+
+141
+00:10:47,270 --> 00:10:51,690
+respiration or sweat بيصير عملية اللي هي خروج
+
+142
+00:10:51,690 --> 00:10:55,610
+التعرق eliminate waste بتطلع مع العرق هذا كتير من
+
+143
+00:10:55,610 --> 00:10:58,910
+ال waste product اللي بيفرزها الجسم and help
+
+144
+00:10:58,910 --> 00:11:01,970
+maintain constant cool temperature الحرارة
+
+145
+00:11:01,970 --> 00:11:06,330
+الداخلية تبع الجسم تمضم عن طريق خروج التعرق هذه
+
+146
+00:11:06,330 --> 00:11:10,430
+فبتقل الحرارة الداخلية و بتطلع على السن
+
+147
+00:11:11,010 --> 00:11:14,710
+أبوكراينيجلانت موجودة داخل الاستشيوط
+
+148
+00:11:14,710 --> 00:11:40,970
+الاسابقوكتانيوكتانيوكتانيوكتانيوكتانيوكتانيو
+
+149
+00:11:43,860 --> 00:11:48,860
+السيرومينس إجلانز modified apocrine-sweetening
+
+150
+00:11:48,860 --> 00:11:54,360
+glands طبعا هي شكلها عاملة زي الـ sweetening اجلاد
+
+151
+00:11:54,360 --> 00:11:59,920
+called و tuber هي عبارة عن تيوب و ملفوفة على بعضها
+
+152
+00:12:01,890 --> 00:12:06,450
+contents into external ear canal بتعطيني اللي هي
+
+153
+00:12:06,450 --> 00:12:14,870
+الشمع هذا اللي موجود في الأذن mixed secretions of
+
+154
+00:12:14,870 --> 00:12:20,850
+sebaceous and serumous glands called ceramide اللي
+
+155
+00:12:20,850 --> 00:12:24,930
+هو ال wax اللي هو الموجود في الأذن functionto
+
+156
+00:12:24,930 --> 00:12:29,150
+protect area from dehydration لو صار في عندنا
+
+157
+00:12:29,150 --> 00:12:32,390
+excessive secretion اللي بتعمل blockage لل ear
+
+158
+00:12:32,390 --> 00:12:39,890
+canal ويبطل الشخص يقدر يسمعروح لحاجة من مكونات ال
+
+159
+00:12:39,890 --> 00:12:45,070
+appendices تبعت ال skin ال hair ال hair موجود على
+
+160
+00:12:45,070 --> 00:12:52,150
+تقريبا على معظم سطح الجسم over entire body except
+
+161
+00:12:52,150 --> 00:12:58,070
+the palm and the hand and sole of the feet and a
+
+162
+00:12:58,070 --> 00:13:03,710
+few other small area fine and soft hairالكوت
+
+163
+00:13:03,710 --> 00:13:08,010
+present before birth ال كورب الانجو اللي هو عبارة
+
+164
+00:13:08,010 --> 00:13:14,830
+عن إيش الزغب اللي بيكون موجود على سطح جلد الطفل
+
+165
+00:13:14,830 --> 00:13:21,240
+فيكون اللي هي كتير كتير ضيف و رقيقcourse pubic and
+
+166
+00:13:21,240 --> 00:13:24,460
+axillary hair اللي موجود في منطقة ال pubis وتحت
+
+167
+00:13:24,460 --> 00:13:28,340
+اللي that developed at the puberty called terminal
+
+168
+00:13:28,340 --> 00:13:34,380
+hair طبعا ال terminal hair بيكون هو بيظهر بعد فترة
+
+169
+00:13:34,380 --> 00:13:41,530
+ال elbowطبعا function of the hair أضيفة الشعر
+
+170
+00:13:41,530 --> 00:13:47,330
+protection شكل حماية heat retention بيحاول على
+
+171
+00:13:47,330 --> 00:13:51,730
+الاحتفاظ بالحرارة prevent loss of conducted heat
+
+172
+00:13:51,730 --> 00:13:56,540
+from the scalp to the surrounding airبيمنع اللي هو
+
+173
+00:13:56,540 --> 00:14:00,280
+تهرب أو هروب الحرارة بيعطيني facial expression
+
+174
+00:14:00,280 --> 00:14:05,900
+إحنا نطلع على الشخص على وجهه الحواجب أحيانا حركة
+
+175
+00:14:05,900 --> 00:14:09,020
+الحواجب بتعطيني facial expression هذا مكشر هذا
+
+176
+00:14:09,020 --> 00:14:13,020
+مبسوط بتعطيني sensory reception و visual
+
+177
+00:14:13,020 --> 00:14:17,800
+identification و chemical signal dispersion
+
+178
+00:14:19,760 --> 00:14:23,340
+أما ال hair follicle اللي هي بصيلات شعر من إيش
+
+179
+00:14:23,340 --> 00:14:28,640
+بتتكون بصيلات الشعر عندنا بتتكون من ال epidermal
+
+180
+00:14:28,640 --> 00:14:34,520
+cells tube-like distribution شكلها عامل زي ال tube
+
+181
+00:14:34,520 --> 00:14:41,520
+زي ما إحنا شايفين بشكل هذا عامل زي كأنها قناة
+
+182
+00:14:41,520 --> 00:14:47,910
+extend into the dermis بتعدي على بتروح منالديرنس و
+
+183
+00:14:47,910 --> 00:14:52,290
+بتروح تطلع لفوق فيه الها hair roots فيها جذر فيها
+
+184
+00:14:52,290 --> 00:14:56,670
+shaft اما احنا شايفين ال shaft تبعها جذر and hair
+
+185
+00:14:56,670 --> 00:15:01,590
+papilla دت epidermal cells لإنه احنا الشعر قلنا
+
+186
+00:15:01,590 --> 00:15:05,460
+مافيش فيه حياةعلى الإطلاق لإن احنا بنلاحظ ان احنا
+
+187
+00:15:05,460 --> 00:15:09,840
+بنقص الشعر لكن ما بنتقلل ان يبقى he did epidermal
+
+188
+00:15:09,840 --> 00:15:14,440
+cells ميلانين في عندها لون لإن بيشوف حسب الصفقة
+
+189
+00:15:14,440 --> 00:15:17,980
+اللي موجودة في الشعر بيظهر عندنا لون الشعر هذا شعر
+
+190
+00:15:17,980 --> 00:15:23,560
+أسود هذا شعر brown هذا شعر أشقر هذا شعر أبيض لما
+
+191
+00:15:23,560 --> 00:15:26,940
+بيفقد الميلانين أو الصفقة اللي موجودة فيه فبتحول
+
+192
+00:15:26,940 --> 00:15:32,510
+الشعر الأبيض اللي احنا بنسميه ال shapeالـ Erector
+
+193
+00:15:32,510 --> 00:15:36,170
+Pili Muscle هي عضلات اللي قلنا عنها انه في حالة
+
+194
+00:15:36,170 --> 00:15:42,870
+الخوف بتأثر على الشعر وبتعمل Erection للشعر نفسها
+
+195
+00:15:42,870 --> 00:15:48,370
+زي ما نقول بتوقف الشعرات فهي صورة توضحية أيضا لل
+
+196
+00:15:48,370 --> 00:15:52,170
+hair and surrounding structure زي ما احنا شايفين
+
+197
+00:15:52,170 --> 00:15:56,230
+في عندنا blood vessels في عندنا hexacrine glands
+
+198
+00:15:56,230 --> 00:16:02,210
+هنا شايفين شكلها coil tube and coilالاركتور باللاي
+
+199
+00:16:02,210 --> 00:16:05,750
+اللى هى العضلات اللى بتوقف الشعر هادي ال hair
+
+200
+00:16:05,750 --> 00:16:09,490
+truth ال hair root و كمان ال hair shaft اللى بيطلع
+
+201
+00:16:09,490 --> 00:16:14,070
+و بيفرج على شكل الشعر اللى احنا بنشوفه و فيه نسباش
+
+202
+00:16:14,070 --> 00:16:18,550
+واسي gland و برضه بتفرز على الشعر ال oil ال
+
+203
+00:16:18,550 --> 00:16:23,150
+ointments اللى نسميها و ال hair root الplexus و كل
+
+204
+00:16:23,150 --> 00:16:29,290
+المكونات اللى ممكن تكون موجودةالـ appearance of
+
+205
+00:16:29,290 --> 00:16:32,050
+the hair في عندنا ال color و ال growth و ال
+
+206
+00:16:32,050 --> 00:16:35,950
+sepachua ciclan ال color result in different
+
+207
+00:16:35,950 --> 00:16:39,330
+amount او distribution type of melanin in the
+
+208
+00:16:39,330 --> 00:16:44,130
+cortex of hair طبعا حسب تركيز كمية و تركيز نوع
+
+209
+00:16:44,130 --> 00:16:47,630
+الميلانين اللي موجود في المكان بيظهر عندنا لون
+
+210
+00:16:47,630 --> 00:16:54,230
+الشعر أما ال growthand rest period alternate here
+
+211
+00:16:54,230 --> 00:16:58,850
+on head average خمسة إنش ذكروتي يعني احنا بيكون في
+
+212
+00:16:58,850 --> 00:17:09,750
+عندنا النمو الشعر عبارة عن خمسة إنش في السنة
+
+213
+00:17:09,750 --> 00:17:14,790
+تقريبا يعني ما يعادل خمستاشر تقريبا سانتي
+
+214
+00:17:17,370 --> 00:17:21,110
+حوالي خمستاشر سانتي، يعني خمسة انش، بنقول كل انش
+
+215
+00:17:21,110 --> 00:17:25,550
+اتنين و نص في السنة أو حسب طبعا الشعر بينمو حسب
+
+216
+00:17:25,550 --> 00:17:29,330
+التغذية اللى موجودة و حسب الطول و احنا كده سي
+
+217
+00:17:29,330 --> 00:17:36,240
+باشواس ال land attached to a secret serumالـ sebum
+
+218
+00:17:36,240 --> 00:17:41,100
+اللي هو ال skin oil into the follicle بترتب هذه ال
+
+219
+00:17:41,100 --> 00:17:44,840
+follicles أو البصيلات بتطلعلي ساعتها الشعار إما
+
+220
+00:17:44,840 --> 00:17:49,140
+يكون دهني أو يكون جاف أو و بباره طبعا ال male
+
+221
+00:17:49,140 --> 00:17:52,440
+paternal bladness اللي هو السلع result from
+
+222
+00:17:52,440 --> 00:17:55,440
+combination of genetic tendency and male sex
+
+223
+00:17:55,440 --> 00:17:59,380
+hormone طبعا السلع بيصير عند الرجال و نادرا ما
+
+224
+00:17:59,380 --> 00:18:06,330
+يصير فيه عند النساءالسلع ممكن يكون genetic لأن
+
+225
+00:18:06,330 --> 00:18:12,330
+الأباء ممكن مثلا هذا مثلا شخص من عيلة بيسلعه فهو
+
+226
+00:18:12,330 --> 00:18:15,430
+بيطلع شعره و طبعا السلع بيبدأ في السن المبكر يعني
+
+227
+00:18:15,430 --> 00:18:19,210
+حوالي سن الخمسة و عشرين بيبدأ علامات السلع تظهر
+
+228
+00:18:19,210 --> 00:18:25,090
+على الشخص و يخف الشعر من من مناطق الأمامية و طبعا
+
+229
+00:18:25,090 --> 00:18:30,060
+الهرومونات الدكارية لها تأثير على هذا الشيءطبعا ال
+
+230
+00:18:30,060 --> 00:18:34,140
+hair thinning and bledness ال alopecia hair
+
+231
+00:18:34,140 --> 00:18:42,430
+thinning يعني بيصير منقول الشعر كتير ضيفممكن يقدي
+
+232
+00:18:42,430 --> 00:18:52,290
+ليعني صلاة أو ممكن يخف الشعر بصورة كتير ملحوظة
+
+233
+00:18:52,290 --> 00:18:56,550
+genetically determined and sex influence condition
+
+234
+00:18:56,550 --> 00:19:02,740
+هي اللي بتأثر على النروح لحاجة اسمها أضافر الأضافر
+
+235
+00:19:02,740 --> 00:19:06,000
+يجزء من الجلد طبعا consist of epidermal cell
+
+236
+00:19:06,000 --> 00:19:09,980
+converted into hard keratin يعني بتتحول الكراتين
+
+237
+00:19:09,980 --> 00:19:13,560
+هذا لها بالمناسبة الشعر كمان لو صار فيه excessive
+
+238
+00:19:13,560 --> 00:19:17,460
+keratin بيصير حاجة اسمها إشرةموجود الإشرة اللى فى
+
+239
+00:19:17,460 --> 00:19:20,600
+الشعر اللى لو حكينا كده شوية بتطلع قشور فهذا
+
+240
+00:19:20,600 --> 00:19:25,120
+excessive keratin خلايا ميتة بتطلع على ال .. على
+
+241
+00:19:25,120 --> 00:19:29,680
+سطح ال .. سطح الجلد فبتعملى قشور هذه القشور اللى
+
+242
+00:19:29,680 --> 00:19:36,530
+احنا بنشوفها عن طريق ال .. الجلد اللونها بيضاأما
+
+243
+00:19:36,530 --> 00:19:40,110
+ال nails فهي consists of epidermic أو epidermal
+
+244
+00:19:40,110 --> 00:19:43,870
+cell converted to hard keratin ال nail visible
+
+245
+00:19:43,870 --> 00:19:48,010
+part of each nail اللي هو واضح بالصورة زي ما احنا
+
+246
+00:19:48,010 --> 00:19:52,970
+شايفينها ال root اللي لها roots part of the nail
+
+247
+00:19:52,970 --> 00:19:58,950
+in a groove hardened by fold of the skin اللي لا
+
+248
+00:20:00,010 --> 00:20:04,310
+اللي عندنا زي نص القمر هادي أو ال moon shape white
+
+249
+00:20:04,310 --> 00:20:08,490
+area نيارستا روت هنا احنا شايفينها يعني في عندنا
+
+250
+00:20:08,490 --> 00:20:14,650
+nail root زيها وفي عندنا ال لونولا وفي عندنا ال
+
+251
+00:20:14,650 --> 00:20:17,750
+nail body وفي عندنا ال free ending هادي اللي احنا
+
+252
+00:20:17,750 --> 00:20:22,350
+بنقصفها طبعا مافيش رحساس بال nails a nail bed
+
+253
+00:20:22,350 --> 00:20:26,170
+layer of epithelium under nail body contains
+
+254
+00:20:26,170 --> 00:20:29,250
+abundant blood vessels في كتير من ال blood vessels
+
+255
+00:20:29,540 --> 00:20:38,460
+موجودة في هذا المكان appeared pink موجودة
+
+256
+00:20:38,460 --> 00:20:43,360
+في هذا المكان appeared pink موجودة في هذا المكان
+
+257
+00:20:43,360 --> 00:20:43,740
+appeared pink موجودة في هذا المكان appeared pink
+
+258
+00:20:43,740 --> 00:20:43,760
+موجودة في هذا المكان appeared pink موجودة في هذا
+
+259
+00:20:43,760 --> 00:20:44,440
+appeared pink موجودة في هذا المكان appeared pink
+
+260
+00:20:44,440 --> 00:20:45,820
+موجودة في هذا المكان appeared pink موجودة في هذا
+
+261
+00:20:45,820 --> 00:20:48,160
+المكان appeared pink موجودة في هذا المكان appeared
+
+262
+00:20:48,160 --> 00:20:52,990
+pink موجودة في هذا المكان appeared pink موجودةنال
+
+263
+00:20:52,990 --> 00:20:57,910
+اكترار النال بمتوسس بصير فيه تكاثر of the cell of
+
+264
+00:20:57,910 --> 00:21:06,210
+striatum granulata يفهم beneath the lunula average
+
+265
+00:21:06,210 --> 00:21:10,850
+growth of pointfive-and-a-half millibar week
+
+266
+00:21:10,850 --> 00:21:15,430
+slightly over one inch per year طبعا احنا بنعرف
+
+267
+00:21:15,430 --> 00:21:19,870
+انه في ناس عندنا بيربوا أدافرهم فممكن تطول هذه
+
+268
+00:21:19,870 --> 00:21:24,450
+الأدافر و هي اصلا مش من السنة انه احنا نرفع يعني
+
+269
+00:21:24,450 --> 00:21:29,780
+تقليم الأدافر من السنة المحببةروح لل burn، ال burn
+
+270
+00:21:29,780 --> 00:21:34,040
+عبارة عن إيش حرق بيصير على سطح الجلد، يعني أول إشي
+
+271
+00:21:34,040 --> 00:21:39,680
+بيتعرض لحرق هو الجلد ال tissue damage of excessive
+
+272
+00:21:39,680 --> 00:21:47,140
+heat أو electricity أو radioactivity or corrosive
+
+273
+00:21:47,140 --> 00:21:53,400
+chemicals that destroy their dentatures protein in
+
+274
+00:21:53,400 --> 00:21:58,410
+the expose of the cellهي called burn أي شيء يعرض
+
+275
+00:21:58,410 --> 00:22:02,450
+الجلد لعملية الاحتراك فهي احنا بنسميها burn
+
+276
+00:22:02,450 --> 00:22:06,570
+generally synthetic effect of burn are greater
+
+277
+00:22:06,570 --> 00:22:12,090
+threatened to life than the local effect طيب يعني
+
+278
+00:22:12,090 --> 00:22:16,230
+ال systemic بشكل خطر ليش؟ ال systemic بشكل خطر
+
+279
+00:22:16,230 --> 00:22:20,970
+لأنه ممكن انه يؤدي لفقدان
+
+280
+00:22:20,970 --> 00:22:26,510
+للسوائل يبقىالـ seriousness of burn is determined
+
+281
+00:22:26,510 --> 00:22:30,210
+by its depth و ال extent و ال area involved و ال
+
+282
+00:22:30,210 --> 00:22:33,990
+burn zone is and general health هذه كلها أوامل
+
+283
+00:22:33,990 --> 00:22:37,690
+بتقول أنه إذا كان هذا الشخص ممكن إذا انحرق ينجح أو
+
+284
+00:22:37,690 --> 00:22:42,090
+لا ينجح سواء كان إذا كان الحرق عميق إذا كان واسع
+
+285
+00:22:42,090 --> 00:22:47,150
+ماخد area كبيرة من الجسم و العمر تبع المريض و ال
+
+286
+00:22:47,150 --> 00:22:51,890
+general health طبيعته قبل الحرقو in the burn area
+
+287
+00:22:51,890 --> 00:22:55,990
+exceeds 70% over half of the victims die يعني إذا
+
+288
+00:22:55,990 --> 00:23:01,210
+كان في حرق نسبته على الجسم أكتر من 70% فهذا المريض
+
+289
+00:23:01,210 --> 00:23:05,890
+أو هذا الشخص اللي اتعرض لحرق ممكن أنه يتوفى
+
+290
+00:23:06,230 --> 00:23:10,330
+distraction of a protein of the skin نتيجة
+
+291
+00:23:10,330 --> 00:23:14,990
+chemical أو electricity أو heat اللي بيصير ممكن
+
+292
+00:23:14,990 --> 00:23:18,470
+يصير shock due to water plasma and plasma protein
+
+293
+00:23:18,470 --> 00:23:22,210
+loss ممكن يدخل المريض في shock ممكن يصير عنده
+
+294
+00:23:22,210 --> 00:23:25,450
+مشاكل في ال circulation أو في ال kidney problem
+
+295
+00:23:25,450 --> 00:23:29,430
+نتيجة ال plasma loss وممكن يصير طبعا الجلب لأنه
+
+296
+00:23:29,430 --> 00:23:34,030
+قلنا هو خط الحماية تبع الجسم من البكتيريا فبالتالي
+
+297
+00:23:34,030 --> 00:23:39,630
+لو صارالشخص عنده حرق هذا تأثر فبصير قابل لل
+
+298
+00:23:39,630 --> 00:23:45,030
+infection وبيقدي طبعا لمشاكل كتير كتير طبعا ال
+
+299
+00:23:45,030 --> 00:23:49,050
+type في عندنا ال first degree بس ال epidermis زي
+
+300
+00:23:49,050 --> 00:23:51,850
+اللي بيصير من ال sun لما بيروح على البحر احنا بس
+
+301
+00:23:51,850 --> 00:23:55,390
+ال epidermis اللي بتأثر first degree burn او sun
+
+302
+00:23:55,390 --> 00:23:57,270
+burn
+
+303
+00:23:58,660 --> 00:24:02,600
+الـ second degree destroy entire epidermis، كل الـ
+
+304
+00:24:02,600 --> 00:24:05,000
+epidermis and part of dermis، يبقى ال thickness
+
+305
+00:24:05,000 --> 00:24:10,360
+تبعه أكتر، fluid fills blister، بيظهر الفقعات على
+
+306
+00:24:10,360 --> 00:24:17,540
+الجسم، على الجلد، deviates are not damaged، ال
+
+307
+00:24:17,540 --> 00:24:20,920
+epidermal deviations، deviatives are not damaged،
+
+308
+00:24:20,920 --> 00:24:25,790
+heals without grafting، يعني ما بيحتاجوالأنه نعمله
+
+309
+00:24:25,790 --> 00:24:31,010
+skin graft أو رؤعة بياخد من تلاتة لاربع weeks and
+
+310
+00:24:31,010 --> 00:24:37,050
+ممكن يؤثر ويصير في عندي scar اش يعني scar مدب
+
+311
+00:24:37,050 --> 00:24:41,950
+بتصير موجودة على ال .. ال .. أما ال third degree
+
+312
+00:24:41,950 --> 00:24:46,330
+هذا بنسمي احنا full thickness أخد ال dermis و ال
+
+313
+00:24:46,330 --> 00:24:51,040
+epidermis و كل ال epidermis deviativesdamage area
+
+314
+00:24:51,040 --> 00:24:58,740
+is not due to loss of sensory nerves لأنه أخد كل
+
+315
+00:24:58,740 --> 00:25:01,840
+ال dermis فال dermis هو موجود في كل ال receptors
+
+316
+00:25:01,840 --> 00:25:04,540
+اللي موجودة على ال skin أو ال nervous receptors أو
+
+317
+00:25:04,540 --> 00:25:11,860
+ال sensory receptors وهذا بيكون الألم فيه أقل طبعا
+
+318
+00:25:11,860 --> 00:25:16,540
+ال rules of 9 هذه راح ندرسها بالتفصيل لما نتكلم عن
+
+319
+00:25:16,540 --> 00:25:22,970
+موضوع الحروبكيف بتقسم الجسم لتسعة في المية تسعة في
+
+320
+00:25:22,970 --> 00:25:28,370
+المية و بتقسم مثلا lower limb بتاخد تسعة في المية
+
+321
+00:25:28,370 --> 00:25:32,910
+تسعة في المية فتنتين مع بعض طنانتعاش أما ال upper
+
+322
+00:25:32,910 --> 00:25:36,830
+limb بتاخد أربع و نص و أربع و نص تنتين يعني تسعة
+
+323
+00:25:36,830 --> 00:25:43,120
+فthe rules of 9s هذه of 9s بتحددنا نسبةانتشار
+
+324
+00:25:43,120 --> 00:25:47,700
+الburn على الجسم اللي قلنا هي ممكن تؤدي لو كانت
+
+325
+00:25:47,700 --> 00:25:53,920
+اكتر من 70% الانتشار فممكن تؤدي الى الوفاة فبياخد
+
+326
+00:25:53,920 --> 00:25:58,760
+ال face اربع و نص اما ال back of the skull بياخد
+
+327
+00:25:58,760 --> 00:26:04,070
+اربع و نص منطقة ال trunk بتاخد تقريبا ستةو تلاتين
+
+328
+00:26:04,070 --> 00:26:08,890
+في المية و ال lower و ال upper لمس و ال anterior
+
+329
+00:26:08,890 --> 00:26:14,910
+او ال posterior ففي نهاية المحصلة بتكون انها مية
+
+330
+00:26:14,910 --> 00:26:20,180
+بالميةطبعا ال cycle of life of the skin في ال
+
+331
+00:26:20,180 --> 00:26:23,660
+children بيكون عندنا smooth unlinked characterized
+
+332
+00:26:23,660 --> 00:26:27,620
+by elasticity and flexibility طبعا عندنا ال skin
+
+333
+00:26:27,620 --> 00:26:36,300
+في في سن الأطفال بيكون كتير skin ضعيف و ناعم
+
+334
+00:26:36,300 --> 00:26:39,580
+بيقولوا يعني بيقولوا انه بشرطه زي الأطفال ليش
+
+335
+00:26:39,580 --> 00:26:42,560
+بشرطه زي الأطفال انها ناعمة كتير فيها كتير من ال
+
+336
+00:26:42,560 --> 00:26:47,910
+..مش دودة، ما بيكونش فيها تجعيد ولا فيها تنيات،
+
+337
+00:26:47,910 --> 00:26:52,270
+characterized by elasticity and flexibility، أقل
+
+338
+00:26:52,270 --> 00:26:55,950
+تعرق وفي عندنا rapid healing يعني الطفل لما بنقصف
+
+339
+00:26:55,950 --> 00:26:59,930
+بعضا فيه من يوم ما بنولد إلا ما نجرحه، لكن باللحظة
+
+340
+00:26:59,930 --> 00:27:04,220
+لحظاتيعني ما بيعدد يوم إلا بيكون صار فيه healing
+
+341
+00:27:04,220 --> 00:27:08,260
+وأي جريح بتتعرض إليه الأطفال طبعا أسهل كتير إنه
+
+342
+00:27:08,260 --> 00:27:13,160
+يلتقى من الأكبر أما الـ Adult ف development and
+
+343
+00:27:13,160 --> 00:27:16,840
+activation of sebaceous and sweaty gland بتزيد،
+
+344
+00:27:16,840 --> 00:27:20,180
+increase the sweat production، بيصير للجسم طبعا
+
+345
+00:27:20,180 --> 00:27:22,980
+هبطلع على الأطفال، فشيلهم ريحة عرق طبعا، أما
+
+346
+00:27:22,980 --> 00:27:26,020
+الأكبر بس تقريب جامعهم بتشعروا بريحة العرق طبعا
+
+347
+00:27:26,020 --> 00:27:29,550
+بعد يومطويل أو يوم قصير أو في أجواء حارة زي اللي
+
+348
+00:27:29,550 --> 00:27:32,290
+احنا عايشينها أحيانا بيصير increase لـsebum
+
+349
+00:27:32,290 --> 00:27:35,530
+production فبصير حاجة أسيمة أكنية احنا ما بنسميه
+
+350
+00:27:35,530 --> 00:27:38,630
+حب الشباب، حب الشباب هذا اللي بيظهر في سن
+
+351
+00:27:38,630 --> 00:27:43,450
+الـadolescents أما الناس الـburly وهدولة اللي
+
+352
+00:27:43,450 --> 00:27:47,270
+بيبين يعني أنت الشخص بتعرف قديش عمره أحيانا من شكل
+
+353
+00:27:47,270 --> 00:27:55,080
+ال skin عندهطبعا بيبدأ التقدم بالعمر بإلغاء ال
+
+354
+00:27:55,080 --> 00:27:59,860
+repair لل skin بيصير عملية ال granulation عملية
+
+355
+00:27:59,860 --> 00:28:05,620
+تجديد ال skin هذه بتصير أقل يبقى skin repair
+
+356
+00:28:05,620 --> 00:28:08,960
+process take longer due to reduce of number and
+
+357
+00:28:08,960 --> 00:28:12,880
+activity of skin cells يعني ال skin بيصير في
+
+358
+00:28:12,880 --> 00:28:16,120
+wrinkles نطلع على الشخص نلاقي في وجهه تجعيد في
+
+359
+00:28:16,120 --> 00:28:21,920
+جسمه تجعيد الجسم بترهدل كمانو بيصير less elastic
+
+360
+00:28:21,920 --> 00:28:26,600
+أو less resilient ال skin alone طبعا response is
+
+361
+00:28:26,600 --> 00:28:29,500
+diminished بصير الجرح ممكن احنا بشوف حتى الناس
+
+362
+00:28:29,500 --> 00:28:32,960
+اللي عندهم أمراض أول ما بيهاجم بيصير في عندهم جرح
+
+363
+00:28:32,960 --> 00:28:37,040
+بيصير صعب الالتئام و كبير بالسم طبعا جرحه بيلتئم
+
+364
+00:28:37,280 --> 00:28:42,420
+أقل أو بياخد وقت أطول من الصغير Become drier due
+
+365
+00:28:42,420 --> 00:28:45,940
+to decrease sebaceous gland activity فيبدأ الجسم
+
+366
+00:28:45,940 --> 00:28:49,560
+الجفاف عشان هي الجسم كبار السن بيحتاج الكثير من
+
+367
+00:28:49,560 --> 00:28:54,620
+الترطيب Alter skin and hair pigmentation بشوف
+
+368
+00:28:54,620 --> 00:28:59,100
+البقع السودة المنتشرة أو البنية المنتشرة على جلد
+
+369
+00:28:59,100 --> 00:29:08,320
+كبار السنطبعا بيقلل ال sweating، بيقلل التعرق، ال
+
+370
+00:29:08,320 --> 00:29:12,320
+blood supply على ال dermis بتقل، ال hair بيصير
+
+371
+00:29:12,320 --> 00:29:18,460
+أضعف و .. و كمان بشير، ال production of vitamin D
+
+372
+00:29:18,460 --> 00:29:24,440
+برضه بيقل، بيصير في عندنا ال skin cancerو هذه بعض
+
+373
+00:29:24,440 --> 00:29:31,140
+المظاهر لـ هى شايفين شكل ال skin في كبار السن طبعا
+
+374
+00:29:31,140 --> 00:29:36,560
+مختلف تماما عن ما كنا نشوف في الصور فى عندنا
+
+375
+00:29:36,560 --> 00:29:40,600
+drying لل epidermis فى عندنا thinning لل epidermis
+
+376
+00:29:40,600 --> 00:29:45,460
+فى عندنا reducing لل sweating gland فى عندنا ال
+
+377
+00:29:45,460 --> 00:29:49,120
+thinningblood dermins reducing the blood supply
+
+378
+00:29:49,120 --> 00:29:52,900
+بتصير كلها attenuated، في change the distribution
+
+379
+00:29:52,900 --> 00:29:58,820
+of the fat and hair، في عندنا a fewer activity
+
+380
+00:29:58,820 --> 00:30:05,360
+follicles، وفي عندنا melanocytes بتصير pale، ال
+
+381
+00:30:05,360 --> 00:30:10,380
+skin بتصير عادة عندهش قدرة على تحمل ال sunlight
+
+382
+00:30:11,070 --> 00:30:15,110
+وبهك احنا بنكون خلصنا من الـ Integumentary System
+
+383
+00:30:15,110 --> 00:30:19,230
+ويعطيكوا العافية ونراكم في الأسبوع القادم ان شاء
+
+384
+00:30:19,230 --> 00:30:19,450
+الله
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..8912352b30623fdcdbad0ab6a945ccdad1899c38
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg_raw.json
@@ -0,0 +1 @@
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665.27, "end": 665.95, "word": " التعرق", "probability": 0.98828125}, {"start": 665.95, "end": 666.33, "word": " هذه", "probability": 0.78076171875}, {"start": 666.33, "end": 667.01, "word": " فبتقل", "probability": 0.92412109375}, {"start": 667.01, "end": 667.53, "word": " الحرارة", "probability": 0.95068359375}, {"start": 667.53, "end": 668.19, "word": " الداخلية", "probability": 0.9947509765625}, {"start": 668.19, "end": 668.43, "word": " و", "probability": 0.392578125}, {"start": 668.43, "end": 669.13, "word": " بتطلع", "probability": 0.887451171875}, {"start": 669.13, "end": 669.53, "word": " على", "probability": 0.927734375}, {"start": 669.53, "end": 670.43, "word": " السن", "probability": 0.4229736328125}], "temperature": 1.0}, {"id": 29, "seek": 70097, "start": 671.01, "end": 700.97, "text": "أبوكراينيجلانت موجودة داخل الاستشيوط الاسابقوكتانيوكتانيوكتانيوكتانيوكتانيوكتانيو", "tokens": [10721, 3555, 2407, 4117, 23557, 9957, 1829, 7435, 1211, 7649, 2655, 3714, 29245, 23328, 3660, 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"text": "نال اكترار النال بمتوسس بصير فيه تكاثر of the cell of striatum granulata يفهم beneath the lunula average growth of point", "tokens": [1863, 6027, 1975, 4117, 2655, 2288, 9640, 2423, 8315, 1211, 4724, 2304, 2655, 41779, 3794, 4724, 9381, 13546, 8978, 3224, 6055, 4117, 5718, 104, 2288, 295, 264, 2815, 295, 3575, 267, 449, 9370, 425, 3274, 7251, 5172, 16095, 17149, 264, 19039, 3780, 4274, 4599, 295, 935], "avg_logprob": -0.8603723175982212, "compression_ratio": 1.2093023255813953, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 1252.21, "end": 1252.99, "word": "نال", "probability": 0.1290435791015625}, {"start": 1252.99, "end": 1254.03, "word": " اكترار", "probability": 0.3005126953125}, {"start": 1254.03, "end": 1254.49, "word": " النال", "probability": 0.593017578125}, {"start": 1254.49, "end": 1255.65, "word": " بمتوسس", "probability": 0.340771484375}, {"start": 1255.65, "end": 1256.05, "word": " بصير", "probability": 0.6404622395833334}, {"start": 1256.05, "end": 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\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..b180f0d049f0b314a6986e32510fe87b2f47047c
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/An--yTeSVyg_raw.srt
@@ -0,0 +1,1568 @@
+1
+00:00:04,910 --> 00:00:08,090
+بسم الله الرحمن الرحيم اليوم بدنا نكمل الموضوع ال
+
+2
+00:00:08,090 --> 00:00:12,910
+skin أو الـ Integumentary System و شرحنا في
+
+3
+00:00:12,910 --> 00:00:16,850
+المحاضرة السابقة طبقات ال skin ال epidermis و
+
+4
+00:00:16,850 --> 00:00:23,250
+dermis و subcutaneous tissue و قلنا أن ال skin هو
+
+5
+00:00:23,250 --> 00:00:28,090
+اللي بيحدد ال colorال color of the body طبعا بتحدد
+
+6
+00:00:28,090 --> 00:00:33,230
+عن طريق ال pigmentation أو ال amount of melanin،
+
+7
+00:00:33,230 --> 00:00:37,570
+في عندنا أكتر من عامل بيحدد لون ال skin، في عندنا
+
+8
+00:00:37,570 --> 00:00:40,830
+genetic factors، في عندنا environmental factors،
+
+9
+00:00:40,830 --> 00:00:43,090
+في عندنا physiological factors
+
+10
+00:00:44,950 --> 00:00:49,930
+عبارة عن ال .. لو تكلمنا عن ال everything مثلا صار
+
+11
+00:00:49,930 --> 00:00:55,650
+في عندنا إحمرار في ال .. في الجسم، معناه إنه صار
+
+12
+00:00:55,650 --> 00:00:59,530
+فيه تركيز لل flood في المنطقة، بنسميها حاجة اسمها
+
+13
+00:00:59,530 --> 00:01:03,130
+بعضه dilatation، ممكن تصير بعضه constriction،
+
+14
+00:01:03,130 --> 00:01:07,920
+بتسكرالأوعية الدموية في عندنا accumulation of
+
+15
+00:01:07,920 --> 00:01:11,240
+carotene أو joindes بيصير في عندنا مشكلة مثلا في
+
+16
+00:01:11,240 --> 00:01:16,300
+ال .. في الكبت أو تركيز ل .. او بيصير اسفرار اللي
+
+17
+00:01:16,300 --> 00:01:22,450
+بيسميه joindes اللي هو الريان مثلا بيزيدبيخللون ال
+
+18
+00:01:22,450 --> 00:01:27,730
+skin أصفر أو العين بياض البنت العين بيصير أصفر في
+
+19
+00:01:27,730 --> 00:01:30,590
+عندنا genetic factors ليش بنقول في ناس بيض في ناس
+
+20
+00:01:30,590 --> 00:01:36,510
+سمر في حدا هذا لونه أسود في ناس لونهم قمحي هذا
+
+21
+00:01:36,510 --> 00:01:41,110
+بيصير أنه الاتنين مثلا الأب والأم بيض فهذا أبنائهم
+
+22
+00:01:41,110 --> 00:01:44,910
+بيطلعوا بيض الأب والأم سمر أبنائهم بيطلعوا سمر
+
+23
+00:01:44,910 --> 00:01:49,820
+وهكذا يبقى في عندناالـ Genetic Factors Varying
+
+24
+00:01:49,820 --> 00:01:52,980
+Amounts of Melanin Varying Size of Melanin
+
+25
+00:01:52,980 --> 00:01:57,960
+Granules أما الـ Environmental Factors فالتعرض للـ
+
+26
+00:01:57,960 --> 00:02:01,660
+Sunlight و الـ Ultraviolet و الـ X-Ray بيعطينا
+
+27
+00:02:01,660 --> 00:02:06,640
+Darkness للملامين بيصير حاجة اسمها Pigmentation of
+
+28
+00:02:06,640 --> 00:02:13,640
+Melanin أما بالنسبة لتحديد
+
+29
+00:02:13,640 --> 00:02:18,100
+اللونعن طريق الميلانين يبقى الـ Basic determinants
+
+30
+00:02:18,100 --> 00:02:23,720
+of skin color عبارة عن الـ quality، الـ quantity
+
+31
+00:02:23,720 --> 00:02:27,520
+of الميلانين الـ type and distribution of ميلانين
+
+32
+00:02:27,520 --> 00:02:31,680
+حدد لللون الـ beta-carotene عبارة عن جروب فياليش
+
+33
+00:02:31,680 --> 00:02:35,820
+pigmentation from the food also contribute in skin
+
+34
+00:02:35,820 --> 00:02:44,480
+color ممكن يتأثر على لون الجل الـ hemoglobinعبارة
+
+35
+00:02:44,480 --> 00:02:49,580
+عن ال .. ال redness اللي بيجي على ال skin أو اللي
+
+36
+00:02:49,580 --> 00:02:52,440
+بيبين على ال skin ال redder .. ال redder skin
+
+37
+00:02:52,440 --> 00:02:56,920
+color when blood flow to the skin increases ممكن
+
+38
+00:02:56,920 --> 00:03:01,500
+صار في عندي تدفق للدم في منطقة معينة فبتصير هذه
+
+39
+00:03:01,500 --> 00:03:06,220
+المنطقة لونها أحمر لو صار الدم إجا على المنطقة
+
+40
+00:03:06,220 --> 00:03:10,220
+اللي كان فيش فيه oxygen فبصير لونها أزرق أو جاي
+
+41
+00:03:10,220 --> 00:03:17,020
+على لون بنفس الجيبلو كان في عندنا ضربات او كذا في
+
+42
+00:03:17,020 --> 00:03:21,540
+الجسم فبنلاقي ان بتيجي حاجة زي ال rainbow او قز
+
+43
+00:03:21,540 --> 00:03:25,860
+قوس قزح على الجسم تطلع انه احنا بنخبط في المكان و
+
+44
+00:03:25,860 --> 00:03:29,180
+بناخدش بالنا من الخط اللي كان بعدها فما بنطلع ممكن
+
+45
+00:03:29,180 --> 00:03:32,720
+نلاقي صار في عندي زي ألوان الطيف موجودة على الجسم
+
+46
+00:03:32,720 --> 00:03:36,900
+تبدأ بالإحمرار بعدين بالإزرقاق بعدين بالصفار بعدين
+
+47
+00:03:37,180 --> 00:03:42,100
+بتروح فهذه كلها بتكون من كميات ال hemoglobin اللي
+
+48
+00:03:42,100 --> 00:03:46,660
+موجودة في المنطقة فيه كمان ال other pigments اللي
+
+49
+00:03:46,660 --> 00:03:53,140
+بتسير ع طريق ال cosmetics يعني بيتعرض لتجميل يعني
+
+50
+00:03:53,140 --> 00:03:56,400
+أشياء تجميلية زي ال tattoo اللي بنعمل اللي برسموا
+
+51
+00:03:56,400 --> 00:03:59,940
+فيه الحواجب أو بيرسموا بيرسموا فيه على أديهم الوشم
+
+52
+00:03:59,940 --> 00:04:01,140
+اللي احنا بنسميه
+
+53
+00:04:05,500 --> 00:04:11,540
+في عندنا أمراض بنقدر إحنا نحددها عن طريق النظر
+
+54
+00:04:11,540 --> 00:04:16,480
+للشخص هذا الانجلدوم ممكن يقولنا إيش نوع المرض اللي
+
+55
+00:04:16,480 --> 00:04:20,460
+هو موجود فيه أو بيعطينا نوع من ال diagnosis اللي
+
+56
+00:04:20,460 --> 00:04:24,880
+أنا على طول بقدر أعرفها زي ال joinedness،
+
+57
+00:04:24,880 --> 00:04:28,420
+الcyanosis والاروثيمة ال joinedness عبارة عن يلوش
+
+58
+00:04:28,420 --> 00:04:33,480
+color of the skinand the whites of the ball built
+
+59
+00:04:33,480 --> 00:04:37,320
+up of yellow bilirubin نتيجة لمشكلة في ال liver في
+
+60
+00:04:37,320 --> 00:04:39,900
+عندنا مشكلة بيكون في الكبد أول ما نطلعت واحد
+
+61
+00:04:39,900 --> 00:04:44,300
+بنلاقي هو مصفر أو أو وجهه أصفر أو اديس أو جلده كله
+
+62
+00:04:44,300 --> 00:04:46,860
+أصفر بيبقى هيك عامل زي الكوركوم لون الكوركوم أو
+
+63
+00:04:46,860 --> 00:04:51,220
+لون الكمون بنعرف أنه هذا في عنده مشكلة نسميها احنا
+
+64
+00:04:51,220 --> 00:04:55,970
+بالعرب الالـ cyanosis بنشوف الشخص بنقوله ما الوجهك
+
+65
+00:04:55,970 --> 00:05:00,150
+أزرق يظهر أنه أنت مش ماكل حاسس فيه إيش، عندك
+
+66
+00:05:00,150 --> 00:05:03,110
+اختناق، عندك كذا أول ما الشخص بيحس بالاختناق أو
+
+67
+00:05:03,110 --> 00:05:05,630
+بيصير فيه عنده مشكلة في عضة القلب بيبين عليه ال
+
+68
+00:05:05,630 --> 00:05:09,530
+cyanosis أو بيخاف أو بيبرد كتير، البربل كتير،
+
+69
+00:05:09,530 --> 00:05:12,810
+بيعطيني اللون ال cyanosis، ليش؟ لأنه بيسبقل تدفق
+
+70
+00:05:12,810 --> 00:05:15,910
+الدم على المكان و الأكسجين في المكان، فبيعطيني
+
+71
+00:05:15,910 --> 00:05:19,710
+blueish color to the nails and the skin وطبعا في
+
+72
+00:05:19,710 --> 00:05:22,970
+حاجة اسمها central cyanosis، في حاجة اسمهاالـ
+
+73
+00:05:22,970 --> 00:05:25,690
+peripheral cyanosis الـ central fear of cyanosis
+
+74
+00:05:25,690 --> 00:05:31,150
+بيكون لو كان اللبس بالتنك أما ال peripheral
+
+75
+00:05:31,150 --> 00:05:38,510
+cyanosis فبصير في الأضراب اللي فيه ما قلنا هي
+
+76
+00:05:38,510 --> 00:05:41,670
+عبارة عن ال redness of the skin عبارة عن the
+
+77
+00:05:41,670 --> 00:05:44,890
+vasodilation أو enlargement of the capillaries in
+
+78
+00:05:44,890 --> 00:05:47,950
+the dermis اللي موجودة في الدرمس فبصير الحمراءلو
+
+79
+00:05:47,950 --> 00:05:51,870
+صار فيه انه inflammation, infection, allergy, to
+
+80
+00:05:51,870 --> 00:05:57,510
+burn or burn بتعرف انه الواحد لما صير عنده حساسية
+
+81
+00:05:57,510 --> 00:06:03,630
+أول مظهر من الحساسية مثلا أكل إشي بتحسس منه زي
+
+82
+00:06:03,630 --> 00:06:08,240
+السمك زي غيرهفممكن على طول يظهر الحساسية على الوجه
+
+83
+00:06:08,240 --> 00:06:12,960
+وعلى الأدين وعلى الكتاف بشكل rashes او احمرار
+
+84
+00:06:12,960 --> 00:06:18,080
+لالجلد اول ما بننجر حقنا فبنلاقي المكان على طول
+
+85
+00:06:18,080 --> 00:06:22,880
+بيصير في عنا حمارأو ان مثلا صار فيه insect bite
+
+86
+00:06:22,880 --> 00:06:28,300
+ايش ال insect bite يعني عضت الحشرات عضت الحشرات
+
+87
+00:06:28,300 --> 00:06:32,540
+أول ما بشوفها بنلاقي بقعة حمراء كده صارت في المكان
+
+88
+00:06:32,540 --> 00:06:36,660
+نتيجة لتدفق الدم عشان تصير عملية ال inflammation و
+
+89
+00:06:36,660 --> 00:06:40,140
+ال phagocytosis اللي احنا اتكلمنا عنها في المحادرة
+
+90
+00:06:40,140 --> 00:06:45,780
+السابقة من وظائف ال skin اللي هي ال protection و
+
+91
+00:06:45,780 --> 00:06:52,100
+ال immuneطيب نروح لحاجة اسمها skin glands ال skin
+
+92
+00:06:52,100 --> 00:06:59,320
+glands عبارة عن غداد موجودة في الجلد أو تحت الجلد
+
+93
+00:06:59,320 --> 00:07:05,510
+طيب الغداد ها دى زى sebaceous glandssebum oily
+
+94
+00:07:05,510 --> 00:07:09,950
+substance that keeps hair and skin soft and pliant
+
+95
+00:07:09,950 --> 00:07:13,970
+يعني هذه الإفرازات تبع ال gland هذه اللي بتعملها
+
+96
+00:07:13,970 --> 00:07:17,810
+تشحيم وتزيد لجسم بتعطينا اللمع على الجلد طبعا
+
+97
+00:07:17,810 --> 00:07:23,150
+الجلد لما يكون جاف بتحسه انه خشن كده ومأشر لكن ال
+
+98
+00:07:23,150 --> 00:07:26,870
+glands هذه ايش وظيفتها انها تطلع ال oils هذه على
+
+99
+00:07:26,870 --> 00:07:29,830
+السطح لاحظوا انه اذا الواحد قعد فترة ما حمم الشعر
+
+100
+00:07:30,150 --> 00:07:33,650
+بتلاقي بيزيد، ليش بيزيد؟ بتطلع هذه الطبقة واضفتها
+
+101
+00:07:33,650 --> 00:07:41,610
+حماية البشرة، بتعطي الجسم الإحساس بالنعومة
+
+102
+00:07:41,610 --> 00:07:45,970
+واللمعان، prevent excessive water use of testicles
+
+103
+00:07:46,140 --> 00:07:49,400
+ان احنا قولنا من ال skin ال skin من وظيفه اصلا انه
+
+104
+00:07:49,400 --> 00:07:52,860
+يعمل regulation ل ال temperature و كمان انه بده
+
+105
+00:07:52,860 --> 00:07:56,400
+يحافظ على السوائل اللي موجودة في الجسم فهذه الطبقة
+
+106
+00:07:56,400 --> 00:08:01,780
+الدهنية او الزيتية اللي موجودة بتمنع خروج السوائل
+
+107
+00:08:01,780 --> 00:08:05,500
+من الاسم usually usually associated with hair
+
+108
+00:08:05,500 --> 00:08:08,580
+follicles طبعا هذه بتكون موجودة مع ال hair احنا
+
+109
+00:08:08,580 --> 00:08:12,240
+بنعرف انه في احنا لو نتكلم عن الشعر بنقول في عندنا
+
+110
+00:08:12,240 --> 00:08:16,220
+شعر جاف و في عندنا شعردهوني وفي عنا شعير عادي، هذا
+
+111
+00:08:16,220 --> 00:08:21,300
+كله بيكون من وين هذه المسميات؟ من كميات ال oil
+
+112
+00:08:21,300 --> 00:08:25,640
+اللي ممكن تنتجها هذه لغلط، lipid components have
+
+113
+00:08:25,640 --> 00:08:29,780
+antifungal activity، طبعا الدهون اللي موجودة فيها
+
+114
+00:08:29,780 --> 00:08:34,270
+بتعمل مضادة للفطريات، simply branchesbranch gland
+
+115
+00:08:34,270 --> 00:08:40,150
+هدى نوعها وشكلها found in the dermis except in the
+
+116
+00:08:40,150 --> 00:08:45,210
+palm and the soles موجودة فى كل ال dermis مع ده ال
+
+117
+00:08:45,210 --> 00:08:50,650
+hands و مع ده ال soul اللى هى الباطن اللى يدوى
+
+118
+00:08:50,650 --> 00:08:55,270
+أسفل القدم secretions increase in adolescents may
+
+119
+00:08:55,270 --> 00:09:01,850
+lead to formation of pimples and blackheads
+
+120
+00:09:05,090 --> 00:09:08,410
+أما الـ sweating gland فقلنا هي عبارة عن ال
+
+121
+00:09:08,410 --> 00:09:13,130
+regulation ل ال heat أو ال temperature وزيفة ال ..
+
+122
+00:09:13,130 --> 00:09:16,290
+احنا بنقول ال sweating gland هي المكيف تبع الجسم،
+
+123
+00:09:16,290 --> 00:09:19,250
+ايش يعني المكيف تبع الجسم؟ اذا ارتفعت درجة حرارة
+
+124
+00:09:19,250 --> 00:09:24,810
+الجسم فبتلاقي بي .. بيصير فيه تعرق، التعرق هذا
+
+125
+00:09:24,810 --> 00:09:28,880
+بيخفف من حرارة الجسم الداخلية و بيطلع معاهكل
+
+126
+00:09:28,880 --> 00:09:34,520
+المواد السامة طبعا widespread in the skin موجودة
+
+127
+00:09:34,520 --> 00:09:38,460
+على كل الجسم originate in deeper dermis or
+
+128
+00:09:38,460 --> 00:09:42,740
+hypodermis هي عبارة عن execrating gland و
+
+129
+00:09:42,740 --> 00:09:47,920
+أبوكرايني gland و siri siri monas gland و ممرري
+
+130
+00:09:47,920 --> 00:09:52,760
+gland اللي هي عبارة عن خلايا الحليب ال siri monas
+
+131
+00:09:52,760 --> 00:09:56,960
+اللي هي الخلايا الصمغية اللي بتفرز السائل الصمغي
+
+132
+00:09:56,960 --> 00:10:03,090
+اللي موجودفي الأذن والخلايا التعرق العراقية والتي
+
+133
+00:10:03,090 --> 00:10:11,510
+تفرز الدموع اكسوكراين اجلانز مست نمورا سويتنج
+
+134
+00:10:11,510 --> 00:10:16,130
+اجلانز بتعطينا هي عبارة small glands distributed
+
+135
+00:10:16,130 --> 00:10:21,150
+over the total body surfaceexception of a small
+
+136
+00:10:21,150 --> 00:10:24,490
+small area يعني ببعض ال area بس اللي مش موجودة لكن
+
+137
+00:10:24,490 --> 00:10:29,670
+هي منتشرة على الجسم كله symbol called tubular يعني
+
+138
+00:10:29,670 --> 00:10:37,470
+عبارة عن tube و ال tube ها دي كده ملوية مع بعضها
+
+139
+00:10:37,470 --> 00:10:42,190
+function throughout the life طبعا كل حياتنا فيه
+
+140
+00:10:42,190 --> 00:10:45,850
+secretions بتطلع عن طريق ال sweet secrets
+
+141
+00:10:47,270 --> 00:10:51,690
+respiration or sweat بيصير عملية اللي هي خروج
+
+142
+00:10:51,690 --> 00:10:55,610
+التعرق eliminate waste بتطلع مع العرق هذا كتير من
+
+143
+00:10:55,610 --> 00:10:58,910
+ال waste product اللي بيفرزها الجسم and help
+
+144
+00:10:58,910 --> 00:11:01,970
+maintain constant cool temperature الحرارة
+
+145
+00:11:01,970 --> 00:11:06,330
+الداخلية تبع الجسم تمضم عن طريق خروج التعرق هذه
+
+146
+00:11:06,330 --> 00:11:10,430
+فبتقل الحرارة الداخلية و بتطلع على السن
+
+147
+00:11:11,010 --> 00:11:14,710
+أبوكراينيجلانت موجودة داخل الاستشيوط
+
+148
+00:11:14,710 --> 00:11:40,970
+الاسابقوكتانيوكتانيوكتانيوكتانيوكتانيوكتانيو
+
+149
+00:11:43,860 --> 00:11:48,860
+السيرومينس إجلانز modified apocrine-sweetening
+
+150
+00:11:48,860 --> 00:11:54,360
+glands طبعا هي شكلها عاملة زي الـ sweetening اجلاد
+
+151
+00:11:54,360 --> 00:11:59,920
+called و tuber هي عبارة عن تيوب و ملفوفة على بعضها
+
+152
+00:12:01,890 --> 00:12:06,450
+contents into external ear canal بتعطيني اللي هي
+
+153
+00:12:06,450 --> 00:12:14,870
+الشمع هذا اللي موجود في الأذن mixed secretions of
+
+154
+00:12:14,870 --> 00:12:20,850
+sebaceous and serumous glands called ceramide اللي
+
+155
+00:12:20,850 --> 00:12:24,930
+هو ال wax اللي هو الموجود في الأذن functionto
+
+156
+00:12:24,930 --> 00:12:29,150
+protect area from dehydration لو صار في عندنا
+
+157
+00:12:29,150 --> 00:12:32,390
+excessive secretion اللي بتعمل blockage لل ear
+
+158
+00:12:32,390 --> 00:12:39,890
+canal ويبطل الشخص يقدر يسمعروح لحاجة من مكونات ال
+
+159
+00:12:39,890 --> 00:12:45,070
+appendices تبعت ال skin ال hair ال hair موجود على
+
+160
+00:12:45,070 --> 00:12:52,150
+تقريبا على معظم سطح الجسم over entire body except
+
+161
+00:12:52,150 --> 00:12:58,070
+the palm and the hand and sole of the feet and a
+
+162
+00:12:58,070 --> 00:13:03,710
+few other small area fine and soft hairالكوت
+
+163
+00:13:03,710 --> 00:13:08,010
+present before birth ال كورب الانجو اللي هو عبارة
+
+164
+00:13:08,010 --> 00:13:14,830
+عن إيش الزغب اللي بيكون موجود على سطح جلد الطفل
+
+165
+00:13:14,830 --> 00:13:21,240
+فيكون اللي هي كتير كتير ضيف و رقيقcourse pubic and
+
+166
+00:13:21,240 --> 00:13:24,460
+axillary hair اللي موجود في منطقة ال pubis وتحت
+
+167
+00:13:24,460 --> 00:13:28,340
+اللي that developed at the puberty called terminal
+
+168
+00:13:28,340 --> 00:13:34,380
+hair طبعا ال terminal hair بيكون هو بيظهر بعد فترة
+
+169
+00:13:34,380 --> 00:13:41,530
+ال elbowطبعا function of the hair أضيفة الشعر
+
+170
+00:13:41,530 --> 00:13:47,330
+protection شكل حماية heat retention بيحاول على
+
+171
+00:13:47,330 --> 00:13:51,730
+الاحتفاظ بالحرارة prevent loss of conducted heat
+
+172
+00:13:51,730 --> 00:13:56,540
+from the scalp to the surrounding airبيمنع اللي هو
+
+173
+00:13:56,540 --> 00:14:00,280
+تهرب أو هروب الحرارة بيعطيني facial expression
+
+174
+00:14:00,280 --> 00:14:05,900
+إحنا نطلع على الشخص على وجهه الحواجب أحيانا حركة
+
+175
+00:14:05,900 --> 00:14:09,020
+الحواجب بتعطيني facial expression هذا مكشر هذا
+
+176
+00:14:09,020 --> 00:14:13,020
+مبسوط بتعطيني sensory reception و visual
+
+177
+00:14:13,020 --> 00:14:17,800
+identification و chemical signal dispersion
+
+178
+00:14:19,760 --> 00:14:23,340
+أما ال hair follicle اللي هي بصيلات شعر من إيش
+
+179
+00:14:23,340 --> 00:14:28,640
+بتتكون بصيلات الشعر عندنا بتتكون من ال epidermal
+
+180
+00:14:28,640 --> 00:14:34,520
+cells tube-like distribution شكلها عامل زي ال tube
+
+181
+00:14:34,520 --> 00:14:41,520
+زي ما إحنا شايفين بشكل هذا عامل زي كأنها قناة
+
+182
+00:14:41,520 --> 00:14:47,910
+extend into the dermis بتعدي على بتروح منالديرنس و
+
+183
+00:14:47,910 --> 00:14:52,290
+بتروح تطلع لفوق فيه الها hair roots فيها جذر فيها
+
+184
+00:14:52,290 --> 00:14:56,670
+shaft اما احنا شايفين ال shaft تبعها جذر and hair
+
+185
+00:14:56,670 --> 00:15:01,590
+papilla دت epidermal cells لإنه احنا الشعر قلنا
+
+186
+00:15:01,590 --> 00:15:05,460
+مافيش فيه حياةعلى الإطلاق لإن احنا بنلاحظ ان احنا
+
+187
+00:15:05,460 --> 00:15:09,840
+بنقص الشعر لكن ما بنتقلل ان يبقى he did epidermal
+
+188
+00:15:09,840 --> 00:15:14,440
+cells ميلانين في عندها لون لإن بيشوف حسب الصفقة
+
+189
+00:15:14,440 --> 00:15:17,980
+اللي موجودة في الشعر بيظهر عندنا لون الشعر هذا شعر
+
+190
+00:15:17,980 --> 00:15:23,560
+أسود هذا شعر brown هذا شعر أشقر هذا شعر أبيض لما
+
+191
+00:15:23,560 --> 00:15:26,940
+بيفقد الميلانين أو الصفقة اللي موجودة فيه فبتحول
+
+192
+00:15:26,940 --> 00:15:32,510
+الشعر الأبيض اللي احنا بنسميه ال shapeالـ Erector
+
+193
+00:15:32,510 --> 00:15:36,170
+Pili Muscle هي عضلات اللي قلنا عنها انه في حالة
+
+194
+00:15:36,170 --> 00:15:42,870
+الخوف بتأثر على الشعر وبتعمل Erection للشعر نفسها
+
+195
+00:15:42,870 --> 00:15:48,370
+زي ما نقول بتوقف الشعرات فهي صورة توضحية أيضا لل
+
+196
+00:15:48,370 --> 00:15:52,170
+hair and surrounding structure زي ما احنا شايفين
+
+197
+00:15:52,170 --> 00:15:56,230
+في عندنا blood vessels في عندنا hexacrine glands
+
+198
+00:15:56,230 --> 00:16:02,210
+هنا شايفين شكلها coil tube and coilالاركتور باللاي
+
+199
+00:16:02,210 --> 00:16:05,750
+اللى هى العضلات اللى بتوقف الشعر هادي ال hair
+
+200
+00:16:05,750 --> 00:16:09,490
+truth ال hair root و كمان ال hair shaft اللى بيطلع
+
+201
+00:16:09,490 --> 00:16:14,070
+و بيفرج على شكل الشعر اللى احنا بنشوفه و فيه نسباش
+
+202
+00:16:14,070 --> 00:16:18,550
+واسي gland و برضه بتفرز على الشعر ال oil ال
+
+203
+00:16:18,550 --> 00:16:23,150
+ointments اللى نسميها و ال hair root الplexus و كل
+
+204
+00:16:23,150 --> 00:16:29,290
+المكونات اللى ممكن تكون موجودةالـ appearance of
+
+205
+00:16:29,290 --> 00:16:32,050
+the hair في عندنا ال color و ال growth و ال
+
+206
+00:16:32,050 --> 00:16:35,950
+sepachua ciclan ال color result in different
+
+207
+00:16:35,950 --> 00:16:39,330
+amount او distribution type of melanin in the
+
+208
+00:16:39,330 --> 00:16:44,130
+cortex of hair طبعا حسب تركيز كمية و تركيز نوع
+
+209
+00:16:44,130 --> 00:16:47,630
+الميلانين اللي موجود في المكان بيظهر عندنا لون
+
+210
+00:16:47,630 --> 00:16:54,230
+الشعر أما ال growthand rest period alternate here
+
+211
+00:16:54,230 --> 00:16:58,850
+on head average خمسة إنش ذكروتي يعني احنا بيكون في
+
+212
+00:16:58,850 --> 00:17:09,750
+عندنا النمو الشعر عبارة عن خمسة إنش في السنة
+
+213
+00:17:09,750 --> 00:17:14,790
+تقريبا يعني ما يعادل خمستاشر تقريبا سانتي
+
+214
+00:17:17,370 --> 00:17:21,110
+حوالي خمستاشر سانتي، يعني خمسة انش، بنقول كل انش
+
+215
+00:17:21,110 --> 00:17:25,550
+اتنين و نص في السنة أو حسب طبعا الشعر بينمو حسب
+
+216
+00:17:25,550 --> 00:17:29,330
+التغذية اللى موجودة و حسب الطول و احنا كده سي
+
+217
+00:17:29,330 --> 00:17:36,240
+باشواس ال land attached to a secret serumالـ sebum
+
+218
+00:17:36,240 --> 00:17:41,100
+اللي هو ال skin oil into the follicle بترتب هذه ال
+
+219
+00:17:41,100 --> 00:17:44,840
+follicles أو البصيلات بتطلعلي ساعتها الشعار إما
+
+220
+00:17:44,840 --> 00:17:49,140
+يكون دهني أو يكون جاف أو و بباره طبعا ال male
+
+221
+00:17:49,140 --> 00:17:52,440
+paternal bladness اللي هو السلع result from
+
+222
+00:17:52,440 --> 00:17:55,440
+combination of genetic tendency and male sex
+
+223
+00:17:55,440 --> 00:17:59,380
+hormone طبعا السلع بيصير عند الرجال و نادرا ما
+
+224
+00:17:59,380 --> 00:18:06,330
+يصير فيه عند النساءالسلع ممكن يكون genetic لأن
+
+225
+00:18:06,330 --> 00:18:12,330
+الأباء ممكن مثلا هذا مثلا شخص من عيلة بيسلعه فهو
+
+226
+00:18:12,330 --> 00:18:15,430
+بيطلع شعره و طبعا السلع بيبدأ في السن المبكر يعني
+
+227
+00:18:15,430 --> 00:18:19,210
+حوالي سن الخمسة و عشرين بيبدأ علامات السلع تظهر
+
+228
+00:18:19,210 --> 00:18:25,090
+على الشخص و يخف الشعر من من مناطق الأمامية و طبعا
+
+229
+00:18:25,090 --> 00:18:30,060
+الهرومونات الدكارية لها تأثير على هذا الشيءطبعا ال
+
+230
+00:18:30,060 --> 00:18:34,140
+hair thinning and bledness ال alopecia hair
+
+231
+00:18:34,140 --> 00:18:42,430
+thinning يعني بيصير منقول الشعر كتير ضيفممكن يقدي
+
+232
+00:18:42,430 --> 00:18:52,290
+ليعني صلاة أو ممكن يخف الشعر بصورة كتير ملحوظة
+
+233
+00:18:52,290 --> 00:18:56,550
+genetically determined and sex influence condition
+
+234
+00:18:56,550 --> 00:19:02,740
+هي اللي بتأثر على النروح لحاجة اسمها أضافر الأضافر
+
+235
+00:19:02,740 --> 00:19:06,000
+يجزء من الجلد طبعا consist of epidermal cell
+
+236
+00:19:06,000 --> 00:19:09,980
+converted into hard keratin يعني بتتحول الكراتين
+
+237
+00:19:09,980 --> 00:19:13,560
+هذا لها بالمناسبة الشعر كمان لو صار فيه excessive
+
+238
+00:19:13,560 --> 00:19:17,460
+keratin بيصير حاجة اسمها إشرةموجود الإشرة اللى فى
+
+239
+00:19:17,460 --> 00:19:20,600
+الشعر اللى لو حكينا كده شوية بتطلع قشور فهذا
+
+240
+00:19:20,600 --> 00:19:25,120
+excessive keratin خلايا ميتة بتطلع على ال .. على
+
+241
+00:19:25,120 --> 00:19:29,680
+سطح ال .. سطح الجلد فبتعملى قشور هذه القشور اللى
+
+242
+00:19:29,680 --> 00:19:36,530
+احنا بنشوفها عن طريق ال .. الجلد اللونها بيضاأما
+
+243
+00:19:36,530 --> 00:19:40,110
+ال nails فهي consists of epidermic أو epidermal
+
+244
+00:19:40,110 --> 00:19:43,870
+cell converted to hard keratin ال nail visible
+
+245
+00:19:43,870 --> 00:19:48,010
+part of each nail اللي هو واضح بالصورة زي ما احنا
+
+246
+00:19:48,010 --> 00:19:52,970
+شايفينها ال root اللي لها roots part of the nail
+
+247
+00:19:52,970 --> 00:19:58,950
+in a groove hardened by fold of the skin اللي لا
+
+248
+00:20:00,010 --> 00:20:04,310
+اللي عندنا زي نص القمر هادي أو ال moon shape white
+
+249
+00:20:04,310 --> 00:20:08,490
+area نيارستا روت هنا احنا شايفينها يعني في عندنا
+
+250
+00:20:08,490 --> 00:20:14,650
+nail root زيها وفي عندنا ال لونولا وفي عندنا ال
+
+251
+00:20:14,650 --> 00:20:17,750
+nail body وفي عندنا ال free ending هادي اللي احنا
+
+252
+00:20:17,750 --> 00:20:22,350
+بنقصفها طبعا مافيش رحساس بال nails a nail bed
+
+253
+00:20:22,350 --> 00:20:26,170
+layer of epithelium under nail body contains
+
+254
+00:20:26,170 --> 00:20:29,250
+abundant blood vessels في كتير من ال blood vessels
+
+255
+00:20:29,540 --> 00:20:38,460
+موجودة في هذا المكان appeared pink موجودة
+
+256
+00:20:38,460 --> 00:20:43,360
+في هذا المكان appeared pink موجودة في هذا المكان
+
+257
+00:20:43,360 --> 00:20:43,360
+appeared pink موجودة في هذا المكان appeared pink
+
+258
+00:20:43,360 --> 00:20:43,360
+موجودة في هذا المكان appeared pink موجودة في هذا
+
+259
+00:20:43,360 --> 00:20:43,360
+المكان appeared pink موجودة في هذا المكان appeared
+
+260
+00:20:43,360 --> 00:20:43,360
+pink موجودة في هذا المكان appeared pink موجودة في
+
+261
+00:20:43,360 --> 00:20:43,360
+هذا المكان appeared pink موجودة في هذا المكان
+
+262
+00:20:43,360 --> 00:20:43,740
+appeared pink موجودة في هذا المكان appeared pink
+
+263
+00:20:43,740 --> 00:20:43,760
+موجودة في هذا المكان appeared pink موجودة في هذا
+
+264
+00:20:43,760 --> 00:20:43,760
+المكان appeared pink موجودة في هذا المكان appeared
+
+265
+00:20:43,760 --> 00:20:43,760
+pink موجودة في هذا المكان appeared pink موجودة في
+
+266
+00:20:43,760 --> 00:20:43,760
+هذا المكان appeared pink موجودة في هذا المكان
+
+267
+00:20:43,760 --> 00:20:44,440
+appeared pink موجودة في هذا المكان appeared pink
+
+268
+00:20:44,440 --> 00:20:45,820
+موجودة في هذا المكان appeared pink موجودة في هذا
+
+269
+00:20:45,820 --> 00:20:48,160
+المكان appeared pink موجودة في هذا المكان appeared
+
+270
+00:20:48,160 --> 00:20:52,990
+pink موجودة في هذا المكان appeared pink موجودةنال
+
+271
+00:20:52,990 --> 00:20:57,910
+اكترار النال بمتوسس بصير فيه تكاثر of the cell of
+
+272
+00:20:57,910 --> 00:21:06,210
+striatum granulata يفهم beneath the lunula average
+
+273
+00:21:06,210 --> 00:21:10,850
+growth of pointfive-and-a-half millibar week
+
+274
+00:21:10,850 --> 00:21:15,430
+slightly over one inch per year طبعا احنا بنعرف
+
+275
+00:21:15,430 --> 00:21:19,870
+انه في ناس عندنا بيربوا أدافرهم فممكن تطول هذه
+
+276
+00:21:19,870 --> 00:21:24,450
+الأدافر و هي اصلا مش من السنة انه احنا نرفع يعني
+
+277
+00:21:24,450 --> 00:21:29,780
+تقليم الأدافر من السنة المحببةروح لل burn، ال burn
+
+278
+00:21:29,780 --> 00:21:34,040
+عبارة عن إيش حرق بيصير على سطح الجلد، يعني أول إشي
+
+279
+00:21:34,040 --> 00:21:39,680
+بيتعرض لحرق هو الجلد ال tissue damage of excessive
+
+280
+00:21:39,680 --> 00:21:47,140
+heat أو electricity أو radioactivity or corrosive
+
+281
+00:21:47,140 --> 00:21:53,400
+chemicals that destroy their dentatures protein in
+
+282
+00:21:53,400 --> 00:21:58,410
+the expose of the cellهي called burn أي شيء يعرض
+
+283
+00:21:58,410 --> 00:22:02,450
+الجلد لعملية الاحتراك فهي احنا بنسميها burn
+
+284
+00:22:02,450 --> 00:22:06,570
+generally synthetic effect of burn are greater
+
+285
+00:22:06,570 --> 00:22:12,090
+threatened to life than the local effect طيب يعني
+
+286
+00:22:12,090 --> 00:22:16,230
+ال systemic بشكل خطر ليش؟ ال systemic بشكل خطر
+
+287
+00:22:16,230 --> 00:22:20,970
+لأنه ممكن انه يؤدي لفقدان
+
+288
+00:22:20,970 --> 00:22:26,510
+للسوائل يبقىالـ seriousness of burn is determined
+
+289
+00:22:26,510 --> 00:22:30,210
+by its depth و ال extent و ال area involved و ال
+
+290
+00:22:30,210 --> 00:22:33,990
+burn zone is and general health هذه كلها أوامل
+
+291
+00:22:33,990 --> 00:22:37,690
+بتقول أنه إذا كان هذا الشخص ممكن إذا انحرق ينجح أو
+
+292
+00:22:37,690 --> 00:22:42,090
+لا ينجح سواء كان إذا كان الحرق عميق إذا كان واسع
+
+293
+00:22:42,090 --> 00:22:47,150
+ماخد area كبيرة من الجسم و العمر تبع المريض و ال
+
+294
+00:22:47,150 --> 00:22:51,890
+general health طبيعته قبل الحرقو in the burn area
+
+295
+00:22:51,890 --> 00:22:55,990
+exceeds 70% over half of the victims die يعني إذا
+
+296
+00:22:55,990 --> 00:23:01,210
+كان في حرق نسبته على الجسم أكتر من 70% فهذا المريض
+
+297
+00:23:01,210 --> 00:23:05,890
+أو هذا الشخص اللي اتعرض لحرق ممكن أنه يتوفى
+
+298
+00:23:06,230 --> 00:23:10,330
+distraction of a protein of the skin نتيجة
+
+299
+00:23:10,330 --> 00:23:14,990
+chemical أو electricity أو heat اللي بيصير ممكن
+
+300
+00:23:14,990 --> 00:23:18,470
+يصير shock due to water plasma and plasma protein
+
+301
+00:23:18,470 --> 00:23:22,210
+loss ممكن يدخل المريض في shock ممكن يصير عنده
+
+302
+00:23:22,210 --> 00:23:25,450
+مشاكل في ال circulation أو في ال kidney problem
+
+303
+00:23:25,450 --> 00:23:29,430
+نتيجة ال plasma loss وممكن يصير طبعا الجلب لأنه
+
+304
+00:23:29,430 --> 00:23:34,030
+قلنا هو خط الحماية تبع الجسم من البكتيريا فبالتالي
+
+305
+00:23:34,030 --> 00:23:39,630
+لو صارالشخص عنده حرق هذا تأثر فبصير قابل لل
+
+306
+00:23:39,630 --> 00:23:45,030
+infection وبيقدي طبعا لمشاكل كتير كتير طبعا ال
+
+307
+00:23:45,030 --> 00:23:49,050
+type في عندنا ال first degree بس ال epidermis زي
+
+308
+00:23:49,050 --> 00:23:51,850
+اللي بيصير من ال sun لما بيروح على البحر احنا بس
+
+309
+00:23:51,850 --> 00:23:55,390
+ال epidermis اللي بتأثر first degree burn او sun
+
+310
+00:23:55,390 --> 00:23:57,270
+burn
+
+311
+00:23:58,660 --> 00:24:02,600
+الـ second degree destroy entire epidermis، كل الـ
+
+312
+00:24:02,600 --> 00:24:05,000
+epidermis and part of dermis، يبقى ال thickness
+
+313
+00:24:05,000 --> 00:24:10,360
+تبعه أكتر، fluid fills blister، بيظهر الفقعات على
+
+314
+00:24:10,360 --> 00:24:17,540
+الجسم، على الجلد، deviates are not damaged، ال
+
+315
+00:24:17,540 --> 00:24:20,920
+epidermal deviations، deviatives are not damaged،
+
+316
+00:24:20,920 --> 00:24:25,790
+heals without grafting، يعني ما بيحتاجوالأنه نعمله
+
+317
+00:24:25,790 --> 00:24:31,010
+skin graft أو رؤعة بياخد من تلاتة لاربع weeks and
+
+318
+00:24:31,010 --> 00:24:37,050
+ممكن يؤثر ويصير في عندي scar اش يعني scar مدب
+
+319
+00:24:37,050 --> 00:24:41,950
+بتصير موجودة على ال .. ال .. أما ال third degree
+
+320
+00:24:41,950 --> 00:24:46,330
+هذا بنسمي احنا full thickness أخد ال dermis و ال
+
+321
+00:24:46,330 --> 00:24:51,040
+epidermis و كل ال epidermis deviativesdamage area
+
+322
+00:24:51,040 --> 00:24:58,740
+is not due to loss of sensory nerves لأنه أخد كل
+
+323
+00:24:58,740 --> 00:25:01,840
+ال dermis فال dermis هو موجود في كل ال receptors
+
+324
+00:25:01,840 --> 00:25:04,540
+اللي موجودة على ال skin أو ال nervous receptors أو
+
+325
+00:25:04,540 --> 00:25:11,860
+ال sensory receptors وهذا بيكون الألم فيه أقل طبعا
+
+326
+00:25:11,860 --> 00:25:16,540
+ال rules of 9 هذه راح ندرسها بالتفصيل لما نتكلم عن
+
+327
+00:25:16,540 --> 00:25:22,970
+موضوع الحروبكيف بتقسم الجسم لتسعة في المية تسعة في
+
+328
+00:25:22,970 --> 00:25:28,370
+المية و بتقسم مثلا lower limb بتاخد تسعة في المية
+
+329
+00:25:28,370 --> 00:25:32,910
+تسعة في المية فتنتين مع بعض طنانتعاش أما ال upper
+
+330
+00:25:32,910 --> 00:25:36,830
+limb بتاخد أربع و نص و أربع و نص تنتين يعني تسعة
+
+331
+00:25:36,830 --> 00:25:43,120
+فthe rules of 9s هذه of 9s بتحددنا نسبةانتشار
+
+332
+00:25:43,120 --> 00:25:47,700
+الburn على الجسم اللي قلنا هي ممكن تؤدي لو كانت
+
+333
+00:25:47,700 --> 00:25:53,920
+اكتر من 70% الانتشار فممكن تؤدي الى الوفاة فبياخد
+
+334
+00:25:53,920 --> 00:25:58,760
+ال face اربع و نص اما ال back of the skull بياخد
+
+335
+00:25:58,760 --> 00:26:04,070
+اربع و نص منطقة ال trunk بتاخد تقريبا ستةو تلاتين
+
+336
+00:26:04,070 --> 00:26:08,890
+في المية و ال lower و ال upper لمس و ال anterior
+
+337
+00:26:08,890 --> 00:26:14,910
+او ال posterior ففي نهاية المحصلة بتكون انها مية
+
+338
+00:26:14,910 --> 00:26:20,180
+بالميةطبعا ال cycle of life of the skin في ال
+
+339
+00:26:20,180 --> 00:26:23,660
+children بيكون عندنا smooth unlinked characterized
+
+340
+00:26:23,660 --> 00:26:27,620
+by elasticity and flexibility طبعا عندنا ال skin
+
+341
+00:26:27,620 --> 00:26:36,300
+في في سن الأطفال بيكون كتير skin ضعيف و ناعم
+
+342
+00:26:36,300 --> 00:26:39,580
+بيقولوا يعني بيقولوا انه بشرطه زي الأطفال ليش
+
+343
+00:26:39,580 --> 00:26:42,560
+بشرطه زي الأطفال انها ناعمة كتير فيها كتير من ال
+
+344
+00:26:42,560 --> 00:26:47,910
+..مش دودة، ما بيكونش فيها تجعيد ولا فيها تنيات،
+
+345
+00:26:47,910 --> 00:26:52,270
+characterized by elasticity and flexibility، أقل
+
+346
+00:26:52,270 --> 00:26:55,950
+تعرق وفي عندنا rapid healing يعني الطفل لما بنقصف
+
+347
+00:26:55,950 --> 00:26:59,930
+بعضا فيه من يوم ما بنولد إلا ما نجرحه، لكن باللحظة
+
+348
+00:26:59,930 --> 00:27:04,220
+لحظاتيعني ما بيعدد يوم إلا بيكون صار فيه healing
+
+349
+00:27:04,220 --> 00:27:08,260
+وأي جريح بتتعرض إليه الأطفال طبعا أسهل كتير إنه
+
+350
+00:27:08,260 --> 00:27:13,160
+يلتقى من الأكبر أما الـ Adult ف development and
+
+351
+00:27:13,160 --> 00:27:16,840
+activation of sebaceous and sweaty gland بتزيد،
+
+352
+00:27:16,840 --> 00:27:20,180
+increase the sweat production، بيصير للجسم طبعا
+
+353
+00:27:20,180 --> 00:27:22,980
+هبطلع على الأطفال، فشيلهم ريحة عرق طبعا، أما
+
+354
+00:27:22,980 --> 00:27:26,020
+الأكبر بس تقريب جامعهم بتشعروا بريحة العرق طبعا
+
+355
+00:27:26,020 --> 00:27:29,550
+بعد يومطويل أو يوم قصير أو في أجواء حارة زي اللي
+
+356
+00:27:29,550 --> 00:27:32,290
+احنا عايشينها أحيانا بيصير increase لـsebum
+
+357
+00:27:32,290 --> 00:27:35,530
+production فبصير حاجة أسيمة أكنية احنا ما بنسميه
+
+358
+00:27:35,530 --> 00:27:38,630
+حب الشباب، حب الشباب هذا اللي بيظهر في سن
+
+359
+00:27:38,630 --> 00:27:43,450
+الـadolescents أما الناس الـburly وهدولة اللي
+
+360
+00:27:43,450 --> 00:27:47,270
+بيبين يعني أنت الشخص بتعرف قديش عمره أحيانا من شكل
+
+361
+00:27:47,270 --> 00:27:55,080
+ال skin عندهطبعا بيبدأ التقدم بالعمر بإلغاء ال
+
+362
+00:27:55,080 --> 00:27:59,860
+repair لل skin بيصير عملية ال granulation عملية
+
+363
+00:27:59,860 --> 00:28:05,620
+تجديد ال skin هذه بتصير أقل يبقى skin repair
+
+364
+00:28:05,620 --> 00:28:08,960
+process take longer due to reduce of number and
+
+365
+00:28:08,960 --> 00:28:12,880
+activity of skin cells يعني ال skin بيصير في
+
+366
+00:28:12,880 --> 00:28:16,120
+wrinkles نطلع على الشخص نلاقي في وجهه تجعيد في
+
+367
+00:28:16,120 --> 00:28:21,920
+جسمه تجعيد الجسم بترهدل كمانو بيصير less elastic
+
+368
+00:28:21,920 --> 00:28:26,600
+أو less resilient ال skin alone طبعا response is
+
+369
+00:28:26,600 --> 00:28:29,500
+diminished بصير الجرح ممكن احنا بشوف حتى الناس
+
+370
+00:28:29,500 --> 00:28:32,960
+اللي عندهم أمراض أول ما بيهاجم بيصير في عندهم جرح
+
+371
+00:28:32,960 --> 00:28:37,040
+بيصير صعب الالتئام و كبير بالسم طبعا جرحه بيلتئم
+
+372
+00:28:37,280 --> 00:28:42,420
+أقل أو بياخد وقت أطول من الصغير Become drier due
+
+373
+00:28:42,420 --> 00:28:45,940
+to decrease sebaceous gland activity فيبدأ الجسم
+
+374
+00:28:45,940 --> 00:28:49,560
+الجفاف عشان هي الجسم كبار السن بيحتاج الكثير من
+
+375
+00:28:49,560 --> 00:28:54,620
+الترطيب Alter skin and hair pigmentation بشوف
+
+376
+00:28:54,620 --> 00:28:59,100
+البقع السودة المنتشرة أو البنية المنتشرة على جلد
+
+377
+00:28:59,100 --> 00:29:08,320
+كبار السنطبعا بيقلل ال sweating، بيقلل التعرق، ال
+
+378
+00:29:08,320 --> 00:29:12,320
+blood supply على ال dermis بتقل، ال hair بيصير
+
+379
+00:29:12,320 --> 00:29:18,460
+أضعف و .. و كمان بشير، ال production of vitamin D
+
+380
+00:29:18,460 --> 00:29:24,440
+برضه بيقل، بيصير في عندنا ال skin cancerو هذه بعض
+
+381
+00:29:24,440 --> 00:29:31,140
+المظاهر لـ هى شايفين شكل ال skin في كبار السن طبعا
+
+382
+00:29:31,140 --> 00:29:36,560
+مختلف تماما عن ما كنا نشوف في الصور فى عندنا
+
+383
+00:29:36,560 --> 00:29:40,600
+drying لل epidermis فى عندنا thinning لل epidermis
+
+384
+00:29:40,600 --> 00:29:45,460
+فى عندنا reducing لل sweating gland فى عندنا ال
+
+385
+00:29:45,460 --> 00:29:49,120
+thinningblood dermins reducing the blood supply
+
+386
+00:29:49,120 --> 00:29:52,900
+بتصير كلها attenuated، في change the distribution
+
+387
+00:29:52,900 --> 00:29:58,820
+of the fat and hair، في عندنا a fewer activity
+
+388
+00:29:58,820 --> 00:30:05,360
+follicles، وفي عندنا melanocytes بتصير pale، ال
+
+389
+00:30:05,360 --> 00:30:10,380
+skin بتصير عادة عندهش قدرة على تحمل ال sunlight
+
+390
+00:30:11,070 --> 00:30:15,110
+وبهك احنا بنكون خلصنا من الـ Integumentary System
+
+391
+00:30:15,110 --> 00:30:19,230
+ويعطيكوا العافية ونراكم في الأسبوع القادم ان شاء
+
+392
+00:30:19,230 --> 00:30:19,450
+الله
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU.srt
new file mode 100644
index 0000000000000000000000000000000000000000..4955ee0783fec0efb16d22462f7edb67d388ab00
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU.srt
@@ -0,0 +1,1382 @@
+1
+00:00:05,870 --> 00:00:09,630
+بسم الله الرحمن الرحيم الصلاة والسلام علي سيدنا
+
+2
+00:00:09,630 --> 00:00:13,730
+محمد سيد المرسلين محاضرتنا الأولى في مساق
+
+3
+00:00:13,730 --> 00:00:18,110
+anatomy للفصل الصيفي إن شاء الله نكون معكم أنا
+
+4
+00:00:18,110 --> 00:00:21,890
+دكتورة علي القشاوي، أخصائية علاج طبيعي وتأهيل، مدير
+
+5
+00:00:21,890 --> 00:00:25,010
+دائرة التأهيل والعلاج الطبيعي في وزارة الصحة،
+
+6
+00:00:25,010 --> 00:00:30,550
+محاضرة بالجامعة الإسلامية بقسم العلاج الطبيعي
+
+7
+00:00:30,550 --> 00:00:37,160
+لكلية العلوم الصحية، إن شاء الله طبعاً يكون محاضرتنا
+
+8
+00:00:37,160 --> 00:00:41,120
+لليوم والمحاضرات اللي جاية من المحاضرات اللي نكون
+
+9
+00:00:41,120 --> 00:00:46,360
+قيمة لأنها مساق تشريح من المساقات الأساسية في ..
+
+10
+00:00:46,360 --> 00:00:51,360
+أي متخصص في مجال العلوم الصحية، لازم نبقى نعرف
+
+11
+00:00:51,360 --> 00:00:55,180
+على الأقل تركيبة الجسم هذا اللي إحنا بنتعامل معاه
+
+12
+00:00:55,260 --> 00:00:59,540
+أنتم متخصصين في مجال العلوم الصحية وطبعاً أنا
+
+13
+00:00:59,540 --> 00:01:02,680
+أتمنى لكم التوفيق لأن أنا بعرف أنه أكيد هيكون معظم
+
+14
+00:01:02,680 --> 00:01:07,580
+الطالبات من كلية الطب والعلوم الصحية، وهؤلاء
+
+15
+00:01:07,580 --> 00:01:11,640
+أكيد يعني هيكونوا في يوم من الأيام خريجين يرفعون
+
+16
+00:01:11,640 --> 00:01:15,840
+الرأس، أكيد هيتعاملوا مع هذا الإنسان، وهيكونوا
+
+17
+00:01:15,840 --> 00:01:21,900
+مثالاً يعني مقدمين خدمة صحية لهذا الشخص و.. وأكيد
+
+18
+00:01:21,900 --> 00:01:28,000
+منهم هيكونوا أناس قادرين على تحسين جودة حياة الإنسان
+
+19
+00:01:28,000 --> 00:01:31,660
+وكذلك على ما نسميه الـ life saving لكي يحافظوا على
+
+20
+00:01:31,660 --> 00:01:39,140
+حياة هذا الإنسان ومنع الإعاقة، وخليني أقول على
+
+21
+00:01:40,290 --> 00:01:44,270
+قدراته، لنحافظ على قدراته الصحية حتى يكون إنسان
+
+22
+00:01:44,270 --> 00:01:47,530
+مستقل، عشان هيك لازم يكون فيه علماً معرفة، بعرف إنكم
+
+23
+00:01:47,530 --> 00:01:50,070
+أنتم من تخصصات مختلفة، منها الطب، منها العلاج
+
+24
+00:01:50,070 --> 00:01:55,210
+الطبيعي، منها البصريات، منها التحاليل الطبية، طبعاً
+
+25
+00:01:55,210 --> 00:02:00,680
+نحاول أن نكون يعني، مش هنخلّي في قِطْع التشريح لأن أكيد
+
+26
+00:02:00,680 --> 00:02:04,580
+أنتم هذا المساق سيعاد إنكم كل واحد حسب التخصص
+
+27
+00:02:04,580 --> 00:02:09,840
+اللي هو بده يروح عليه، خلينا نتعرف في البداية على
+
+28
+00:02:09,840 --> 00:02:16,360
+التعريف، الـ anatomy، الـ anatomy هو علم التشريح، طيب
+
+29
+00:02:16,360 --> 00:02:20,860
+هذه الكلمة من وين اجت؟ اجت هي كلمة إغريقية أو
+
+30
+00:02:20,860 --> 00:02:28,600
+Greek، معناها to cut up، أنها نقطع أو نـ dissect the
+
+31
+00:02:28,600 --> 00:02:31,560
+science that deals with the structure of the body
+
+32
+00:02:31,560 --> 00:02:34,840
+طول عمرنا بنسمع عن حاجة اسمها anatomy وحاجة اسمها
+
+33
+00:02:34,840 --> 00:02:38,400
+physiology، ممكن أنا شخصياً لما درست درستهم اثنين مع
+
+34
+00:02:38,400 --> 00:02:42,640
+بعض في كتاب اسمه anatomy and physiology، كان سؤال
+
+35
+00:02:42,640 --> 00:02:45,600
+بيطرح الفصل بين الـ anatomy والـ physiology، لأن أنت الـ
+
+36
+00:02:45,600 --> 00:02:48,980
+anatomy بيهتم بالـ structure تبع الأشياء، أما الـ
+
+37
+00:02:48,980 --> 00:02:52,060
+physiology بيهتم بالوظيفة، يعني عشان لازم تعرف
+
+38
+00:02:52,060 --> 00:02:57,410
+الوظيفة، لازم تعرف الـ structure، ما فيش إمكانية صعوبة
+
+39
+00:02:57,410 --> 00:03:01,230
+الفصل ما بين هذول إلا إنه في بعض المساقات بتفصل ما
+
+40
+00:03:01,230 --> 00:03:04,690
+بينهم زي المساق اللي إحنا هنتكلم بس عن الـ structure
+
+41
+00:03:04,690 --> 00:03:09,150
+تبع الـ body وأجزاء الـ body المختلفة، طيب ما هيش
+
+42
+00:03:09,150 --> 00:03:12,710
+أنواع الـ anatomy؟ فيه عندنا الـ gross anatomy اللي
+
+43
+00:03:12,710 --> 00:03:16,650
+هو بيهتم بالمظهر الخارجي أو اللي يُرى بالعين
+
+44
+00:03:16,650 --> 00:03:20,750
+المجردة، فيه الـ microscopic anatomy اللي ما بنقدرش
+
+45
+00:03:20,750 --> 00:03:24,810
+نشوفه بالعين المجردة، بنشوفه تحت الـ microscope، الـ
+
+46
+00:03:24,810 --> 00:03:29,170
+developmental، بنشوف التطور، علم التطور الأشخاص أو
+
+47
+00:03:29,170 --> 00:03:33,330
+الأفراد من الـ embryology لحد ما يصير الشخص كبير
+
+48
+00:03:33,330 --> 00:03:36,990
+بالسن، وفيه الـ comparative anatomy اللي بيقارن
+
+49
+00:03:36,990 --> 00:03:41,490
+الكائنات مع بعضها أو الفقريات مع بعضها، لو تكلمنا
+
+50
+00:03:41,490 --> 00:03:46,620
+عن الـ human beings، طيب إيش هو الـ gross anatomy؟ الـ
+
+51
+00:03:46,620 --> 00:03:51,240
+gross anatomy هو العلم اللي بيهتم بالـ structure
+
+52
+00:03:51,240 --> 00:03:55,060
+with naked eyes، يعني أنا بعيني بقدر أشوف الشخص
+
+53
+00:03:55,060 --> 00:04:00,050
+هذا، بقدر أقول الشخص قدامي، هذا فيه head، فيه
+
+54
+00:04:00,050 --> 00:04:02,910
+shoulders، فيه upper limbs، فيه lower limbs، فيه
+
+55
+00:04:02,910 --> 00:04:09,770
+trunk، فيه abdomen، هذا كله بشوفه، طيب لو فتحت أنا
+
+56
+00:04:09,770 --> 00:04:14,910
+ومسكت مشرط وجئت على جثة أو ومسكت skeleton بقدر
+
+57
+00:04:14,910 --> 00:04:21,330
+أقول والله هذه العظمة هي الـ femur، هذه الـ scapula،
+
+58
+00:04:21,330 --> 00:04:25,930
+بشوفها بعيني، ما محتاج أنا أحطها under microscope، كل
+
+59
+00:04:25,930 --> 00:04:30,630
+هذه الأشياء هنتعرف عليها لما نجي نستخدم أو نتعرف
+
+60
+00:04:30,630 --> 00:04:35,910
+على الـ region by region، فبنتكلم عنه أنواعه، طيب الـ
+
+61
+00:04:35,910 --> 00:04:38,870
+gross anatomy مش بتتكلم regionally، يعني بيستخدم الـ
+
+62
+00:04:38,870 --> 00:04:40,890
+upper part of the body، lower part of the
+
+63
+00:04:40,890 --> 00:04:43,610
+extremities، الـ appendicular system اللي هو الـ
+
+64
+00:04:43,610 --> 00:04:49,170
+trunk والـ head، الـ axial.. sorry، الـ axial اللي هو
+
+65
+00:04:49,170 --> 00:04:52,510
+الـ head والـ trunk، الـ appendicular هي الأطراف، الـ
+
+66
+00:04:52,510 --> 00:04:55,770
+regional لكن الـ system يستخدم، بيتكلم عن الـ
+
+67
+00:04:55,770 --> 00:04:59,150
+respiratory system، الـ cardiovascular system، عن الـ
+
+68
+00:04:59,150 --> 00:05:02,430
+endocrine
+
+69
+00:05:02,430 --> 00:05:06,210
+system، الـ integumentary system، كل الـ systems في 11
+
+70
+00:05:06,210 --> 00:05:12,050
+system of the body، ممكن يتدرسوا one by one، الـ
+
+71
+00:05:12,050 --> 00:05:15,810
+gastrointestinal وغيره، هنشوفهم كما نشوف، أما الـ
+
+72
+00:05:15,810 --> 00:05:19,610
+microscopic فهو وين؟ هذا بيهتم بالأشياء اللي إحنا
+
+73
+00:05:19,610 --> 00:05:22,930
+ما بنقدرش نشوفها بالعين المجردة، نشوفها under
+
+74
+00:05:22,930 --> 00:05:28,250
+microscope، الـ cytology والـ histology والـ
+
+75
+00:05:28,250 --> 00:05:33,470
+organology، الـ cytology بيشوف الخلية وبيحاول يدرس
+
+76
+00:05:33,470 --> 00:05:37,490
+هذه الخلية، إيش خصائص الخلية هذه؟ فيها nucleus، مش
+
+77
+00:05:37,490 --> 00:05:40,270
+فيها nucleus، فيها cytoplasm، فيها.. وكل هذه
+
+78
+00:05:40,270 --> 00:05:43,610
+الأشياء مين اللي بيشوفها؟ علم الـ cytology، under
+
+79
+00:05:43,610 --> 00:05:47,330
+microscope، التيلوجي بتتكلم عن الـ tissue نفسها،
+
+80
+00:05:47,330 --> 00:05:51,390
+هنقول إيه؟ إن الـ tissue مكون أساسي مثلاً للـ organ،
+
+81
+00:05:51,390 --> 00:05:54,970
+مجموعة من الـ tissues بتتحد، بتكون لها خواص معينة بتعمل
+
+82
+00:05:54,970 --> 00:05:58,530
+tissue، خواص الـ tissue هذه اللي هي لما بتتركب مع
+
+83
+00:05:58,530 --> 00:06:01,990
+بعضها أو بتتحد مع بعضها، بتتكون لي حاجة اسمها
+
+84
+00:06:01,990 --> 00:06:08,270
+organ، فكل واحد من هذه المكونات ممكن تندرس
+
+85
+00:06:08,270 --> 00:06:13,810
+under microscope، أما الـ Developmental فهو بيهتم
+
+86
+00:06:13,810 --> 00:06:18,490
+بالـ anatomical changes during الـ life cycle، طيب الـ
+
+87
+00:06:18,490 --> 00:06:22,410
+life cycle هذه بتبدأ من الـ embryology وبعدين
+
+88
+00:06:22,410 --> 00:06:28,290
+بتبدأ التطور، التطور الجنيني من اتحاد الـ sperm مع الـ
+
+89
+00:06:28,290 --> 00:06:34,050
+ovum لحد ما يتكون الجنين في يوم ما يصير فيه عملية
+
+90
+00:06:34,050 --> 00:06:37,230
+ولادة، فهذا بيسموه embryology، أما الـ postnatal
+
+91
+00:06:37,230 --> 00:06:43,670
+development اللي بيبدأ من عمر واحد لنهاية العمر سواء
+
+92
+00:06:43,670 --> 00:06:48,850
+إما بيبدأ العمر بأيام، لشهور، لسنوات أو سنوات عديدة
+
+93
+00:06:48,850 --> 00:06:54,530
+ولو الإنسان وصل فيه لعمر متقدم بالسن، فهذا بيسمى
+
+94
+00:06:54,530 --> 00:06:58,470
+anatomical difference، طبعاً فيه فرق بين عظمة الـ baby
+
+95
+00:06:58,470 --> 00:07:01,790
+اللي هي معظمها cartilage، مع عظمة الـ adolescence
+
+96
+00:07:01,790 --> 00:07:06,790
+اللي هي مبنية هنا في سَياق ossification، معظمة الـ
+
+97
+00:07:06,790 --> 00:07:12,710
+old ages اللي هي osteoporotic، فهنا هذه الدراسة
+
+98
+00:07:12,710 --> 00:07:19,380
+بتصير معمقة على جميع الخلايا، أما الـ comparative
+
+99
+00:07:19,380 --> 00:07:22,420
+anatomy اللي هو بيقارن الفقريات بعضها، الـ
+
+100
+00:07:22,420 --> 00:07:25,400
+comparison of the structure between organisms، يعني
+
+101
+00:07:25,400 --> 00:07:31,280
+إحنا شايفين hand لـ human ولـ dog ولـ bird، كل واحدة
+
+102
+00:07:31,280 --> 00:07:35,940
+هادي يد وهادي يد وهادي يد، كل واحدة لها وظيفة
+
+103
+00:07:36,600 --> 00:07:42,120
+هي يد حقيقي، لكن هي الوظيفة اللي بتقدرها حسب الشخص
+
+104
+00:07:42,120 --> 00:07:48,140
+أو الكائن الحي اللي هي بتتبع له، وبنشوف فيه تشابه
+
+105
+00:07:48,140 --> 00:07:53,040
+أحياناً بيكون أن معظمها فيها عظمة الهيوميراس، وبعدين
+
+106
+00:07:53,040 --> 00:07:59,820
+عظمتين تحت وهكذا، يبقى هي الـ comparison between
+
+107
+00:07:59,820 --> 00:08:04,760
+structures among vertebrate classes أو الفقريات
+
+108
+00:08:04,760 --> 00:08:13,420
+تمام؟ هو العلم الخاص بوظيفة
+
+109
+00:08:13,420 --> 00:08:18,580
+الأعضاء، إيش هي وظيفة الأعضاء؟ هو صحيح جداً أن أقول
+
+110
+00:08:18,580 --> 00:08:24,280
+أن هناك فصل بين الـ structure وبين الـ function،
+
+111
+00:08:24,280 --> 00:08:29,910
+العين في وظيفتها، المشروع، طيب لازم أعرف إيش هي
+
+112
+00:08:29,910 --> 00:08:34,370
+العين، إيش تركيبة العين، كيف بتحقق عملية الرؤية،
+
+113
+00:08:34,370 --> 00:08:38,850
+طبعاً؟ اليد وظيفتها إمكانية الوصول للأشياء، طيب كيف
+
+114
+00:08:38,850 --> 00:08:42,930
+لازم أعرف الـ structure؟ هي كلها عظمة واحدة، هي
+
+115
+00:08:42,930 --> 00:08:46,470
+مجموعة من العظام والمفاصل، طيب فيه عضلات، طيب العضلات
+
+116
+00:08:46,470 --> 00:08:49,700
+هذه إيش بتعمل؟ وظيفتها، طيب أنا لازم أعرف أن هذه
+
+117
+00:08:49,700 --> 00:08:52,100
+العضلة إيش تركيبتها، وإيش طولها، وإيش origin وإيش
+
+118
+00:08:52,100 --> 00:08:55,060
+insertion، بعد هيك الـ function تبعيتها، كيف أنا بدي
+
+119
+00:08:55,060 --> 00:08:57,760
+أعرفها؟ أعرفها عن طريق الفيسيولوجيا أو علم
+
+120
+00:08:57,760 --> 00:09:00,220
+الفيسيولوجيا، طيب العضلة هذه إيش بتفرق عن العضلة هذه؟
+
+121
+00:09:00,220 --> 00:09:03,200
+عضلة رباعية وهذه عضلة ثنائية، عضلة طويلة، هذه عضلة
+
+122
+00:09:03,200 --> 00:09:06,360
+قصيرة، هذه شكلها عاملة زي الريشة، هذه شكلها، طيب و
+
+123
+00:09:06,360 --> 00:09:10,620
+بعدين كل واحدة بتقدم وظيفة تتناسب معها، يبقى أنا
+
+124
+00:09:10,620 --> 00:09:14,040
+لازم أبقى عارفة الـ anatomy عشان أنا أقدر أدرس
+
+125
+00:09:14,040 --> 00:09:15,580
+الفيسيولوجيا
+
+126
+00:09:18,440 --> 00:09:21,280
+طيب نشوف الـ structural level of the organization
+
+127
+00:09:22,370 --> 00:09:29,690
+الحين بتتكلم عن الذرة والأجزاء وكيف بتتكون هذا الـ
+
+128
+00:09:29,690 --> 00:09:34,510
+body كامل، بتبدأ من أشياء صغيرة جداً تتحد مع بعضها
+
+129
+00:09:34,510 --> 00:09:38,010
+تصير أكبر شوية، تتحد مع بعضها تصير أكبر أكثر، تتحد
+
+130
+00:09:38,010 --> 00:09:41,870
+مع بعضها تصير مجموعة من الـ من الـ من الـ cells اللي
+
+131
+00:09:41,870 --> 00:09:45,130
+هي متشابهة، بتعمل الـ tissue، مجموعة من الـ tissues
+
+132
+00:09:45,130 --> 00:09:48,970
+متشابهة بتعمل الـ organ، مجموعة من الـ organs بتعمل
+
+133
+00:09:48,970 --> 00:09:55,500
+الـ الـ body هذا أو الـ systems، الـ systems كلها
+
+134
+00:09:55,500 --> 00:10:02,420
+بتعمل الـ body، وهنشوفهم واحدة واحدة، الـ atom زي الـ
+
+135
+00:10:02,420 --> 00:10:08,120
+carbon، الـ hydrogen، الـ oxygen، الـ atom the smallest
+
+136
+00:10:08,120 --> 00:10:13,480
+the smallest، أصغر واحدة particle of an element
+
+137
+00:10:13,480 --> 00:10:19,040
+atom combined with or react مع other atom، اثنين atom
+
+138
+00:10:19,040 --> 00:10:24,140
+أو أكثر بيعمل لي حاجة اسمها molecule، الـ molecule اللي
+
+139
+00:10:24,140 --> 00:10:27,620
+هتطلعني من الـ carbon لحاله، صار عندي carbon dioxide
+
+140
+00:10:27,620 --> 00:10:32,480
+ثاني أكسيد الكربون، صار عندي H2O اللي هو الـ water
+
+141
+00:10:32,480 --> 00:10:36,600
+تمام؟ هذه الـ molecules defined as particle
+
+142
+00:10:36,600 --> 00:10:41,130
+composed of two or more joined atoms، يعني في عندي
+
+143
+00:10:41,130 --> 00:10:45,410
+ذرتين اتحدوا فعملوا لي عملوا لي جزيء اللي هو صار شيء
+
+144
+00:10:45,410 --> 00:10:51,750
+ثاني مختلف، الهيدروجين لحاله مع الكربون مع الـ..مع
+
+145
+00:10:51,750 --> 00:10:55,810
+الأكسجين كان هذا لحاله وهذا لحاله، غازين مختلفين
+
+146
+00:10:55,810 --> 00:11:02,130
+لما اتحدوا مع بعض عملوا ماء، فصار في عندي جزيء، طيب
+
+147
+00:11:02,130 --> 00:11:05,050
+الجزيء لو كان كبير شوية زي الـ carbohydrate،
+
+148
+00:11:05,050 --> 00:11:08,230
+الـ dehydrated أو الـ lipid أو البروتين، اللي هو
+
+149
+00:11:08,230 --> 00:11:15,770
+البروتينات والدهون، كل هذه عبارة عن إيش؟ Large
+
+150
+00:11:15,770 --> 00:11:20,810
+molecule، موليكول بس إيش؟ كبير، الـ macro
+
+151
+00:11:20,810 --> 00:11:24,610
+molecules combined with others، macro molecules،
+
+152
+00:11:24,610 --> 00:11:27,270
+كلهم بتتحد مع بعض عشان يعملوا الـ organelle، الـ
+
+153
+00:11:27,270 --> 00:11:31,740
+organelle أصغر من الـ cell، زي الـ cell membrane،
+
+154
+00:11:31,740 --> 00:11:36,040
+الـ nucleus، الـ ribosomes، هي defined as the small
+
+155
+00:11:36,040 --> 00:11:40,300
+organ of the cell، organelle هي اسم الـ organ of the
+
+156
+00:11:40,300 --> 00:11:43,600
+cell، هي الـ cell which perform a particular
+
+157
+00:11:43,600 --> 00:11:48,320
+function، الـ organelles بتتحد مع بعض فبيعملوا لي حاجة
+
+158
+00:11:48,320 --> 00:11:53,660
+اسمها الـ cell، الـ cell هذه بتبدأ تتغير أو بتبدأ
+
+159
+00:11:53,660 --> 00:11:59,880
+تاخد نمط معين أو شكل معين أو خصائص معينة عشان تقدر
+
+160
+00:11:59,880 --> 00:12:04,760
+وظيفة، اتحدت مع بعضها بتعمل الـ tissue، في بعض الـ
+
+161
+00:12:04,760 --> 00:12:09,960
+cells مستقلة بذاتها زي الـ RBCs أو الـ Red Blood
+
+162
+00:12:09,960 --> 00:12:14,090
+Cells، Defined as the basic unit of the structure
+
+163
+00:12:14,090 --> 00:12:18,530
+and function of living organisms، هي الخلية
+
+164
+00:12:18,530 --> 00:12:27,480
+الأساسية، الـ basic unit اللي بتعمل بتحدد شكلها بتعمل
+
+165
+00:12:27,480 --> 00:12:33,500
+شكل عشان تحدد هي وين، هي خلية عصبية ولا خلية..
+
+166
+00:12:33,500 --> 00:12:40,600
+خلية قلب ولا هي خلية، اتحاد هيعمل لي الـ muscle أو
+
+167
+00:12:40,600 --> 00:12:47,630
+خلية، هذا الاتحاد هيعمل لي الـ bone أو غيره، يبقى بعض الـ
+
+168
+00:12:47,630 --> 00:12:52,290
+cells have all the machinery that they need to
+
+169
+00:12:52,290 --> 00:12:59,170
+live، يعني بتعيش مستقلة زي الـ RBCs، هي لها وظيفة
+
+170
+00:12:59,170 --> 00:13:06,230
+مُستقلة إن هي بتحمل الـ oxygen أو transport الـ
+
+171
+00:13:06,230 --> 00:13:11,820
+oxygen، طبعاً مجموعة من الـ cells طبعاً نقول مجموعة من
+
+172
+00:13:11,820 --> 00:13:16,260
+الـ cells زي الـ RBCs والـ white blood cells والـ
+
+173
+00:13:16,260 --> 00:13:21,560
+plasma بيكون الدم مع بعض، مش لحالها الـ RBCs، طيب لو
+
+174
+00:13:21,560 --> 00:13:25,400
+اتكلمنا على مجموعة من الـ neurons اللي هي الـ cell
+
+175
+00:13:25,400 --> 00:13:29,800
+
+223
+00:17:01,610 --> 00:17:10,150
+كلها هذه أنظمة اقتصادية ودول، طيب هاي emirates
+
+224
+00:17:10,150 --> 00:17:15,210
+الرسم التوضيحي ببسط العملية بقولنا كيف بتبدأ من
+
+225
+00:17:15,210 --> 00:17:19,650
+اتحادات الـ atoms عشان نروح لـ الـ molecules مجموعة
+
+226
+00:17:19,650 --> 00:17:25,580
+الـ molecules ايش بتعمل؟ هي بتكون لـ الـ muscle بتكون
+
+227
+00:17:25,580 --> 00:17:32,100
+الـ smooth tissues بتكون organ، مجموعة الـ organs
+
+228
+00:17:32,100 --> 00:17:41,080
+بتعملي الـ living body زي هاي التفاحة، طبعا هاي
+
+229
+00:17:41,080 --> 00:17:50,740
+التفاحة فيها بتمثل الـ body تبعت الإنسان
+
+230
+00:17:50,740 --> 00:17:55,820
+هنا باختصار الـ 11 body systems اللي احنا اتكلمنا
+
+231
+00:17:55,820 --> 00:18:03,480
+عنهم، هنتكلم عنهم شوية زي... مش عارف من أين أبدأ
+
+232
+00:18:03,480 --> 00:18:09,040
+أن نبدأ من الـ Integumentary System اللي هو السطحي
+
+233
+00:18:09,040 --> 00:18:14,800
+الخارجي، الـ skeletal system، الـ muscular system، الـ
+
+234
+00:18:14,800 --> 00:18:19,300
+nervous system، الـ circulatory system، الـ endocrine
+
+235
+00:18:19,300 --> 00:18:22,560
+الـ lymphatic، الـ digestive، الـ respiratory، الـ
+
+236
+00:18:22,560 --> 00:18:27,160
+urinary، الـ reproductive system، هدولة مجموعة من الـ
+
+237
+00:18:27,160 --> 00:18:32,160
+systems اللي بيكونوا الـ body، وهنتعرف عليهم one by
+
+238
+00:18:32,160 --> 00:18:36,830
+one، نبدأ في الـ Integumentary System، احنا بنسميه هو
+
+239
+00:18:36,830 --> 00:18:42,410
+خط الدفاع الأول عن جسم الإنسان، أول حاجة احنا
+
+240
+00:18:42,410 --> 00:18:47,190
+بتصيبنا، بنقول: من وين أخدنا المستقبلات؟ هذه موجودة
+
+241
+00:18:47,190 --> 00:18:51,590
+في الـ skin، ابنان الجرح، الجرح البسيط قد يؤدي أحياناً
+
+242
+00:18:51,590 --> 00:18:56,310
+إلى بتر في أصبع، بتر في القدم، ليه؟ لأن هو جرح صغير
+
+243
+00:18:56,310 --> 00:19:02,040
+مع ضعيف في الدورة الدموية، مع قصور، مع نقص، خلينا نقول if circulation في
+
+244
+00:19:02,040 --> 00:19:06,000
+المكان، ممكن infection أو gangrene أو whatever
+
+245
+00:19:06,000 --> 00:19:12,280
+هذا بس بدأ في الـ skin، الـ regulatory system هو
+
+246
+00:19:12,280 --> 00:19:16,700
+عبارة عن الـ skin، الـ hairs، و الـ nails، طب الـ skin
+
+247
+00:19:16,700 --> 00:19:20,440
+فيه إحساس، الـ hair مش فيها إحساس، الـ nails مش فيها
+
+248
+00:19:20,440 --> 00:19:24,680
+إحساس، ليش؟ ربنا خلق الأظافر مش فيها إحساس عشان
+
+249
+00:19:24,680 --> 00:19:28,080
+نقدر نقصّها، تخيلوا إن لو كلنا بدنا نقصّ أظافرنا
+
+250
+00:19:28,080 --> 00:19:31,660
+أيدينا، أو أظافر أيدينا، أو أظافر أرجلنا، بدنا نصير
+
+251
+00:19:31,660 --> 00:19:35,140
+نصيح أو بدنا نمنع عن قصّها، أو كل ما حد مسكها
+
+252
+00:19:35,140 --> 00:19:38,120
+بمقصّ، عمل في شعر، وهكذا، بدنا نصير نصرخ، معناه الناس
+
+253
+00:19:38,120 --> 00:19:41,800
+بتبقى ماشية بأظافر طويلة، وأشعار طويلة، لكن الـ
+
+254
+00:19:41,800 --> 00:19:45,940
+skin هذا، هذا المنبه على طول، أول ما بينضغط أو
+
+255
+00:19:45,940 --> 00:19:51,160
+بتسيبه، لسة قعدت بوس شوكة، أي شيء، الإنسان بيتنبّه
+
+256
+00:19:51,160 --> 00:19:55,700
+فورا، external covering، كمان بيعطيني صورة جمالية
+
+257
+00:19:55,700 --> 00:20:00,360
+لجسم، بيغطي كل أجزاء الجسم، الـ underlying tissue
+
+258
+00:20:00,360 --> 00:20:06,500
+organs، كمان بيعطيني protection، بيحفظ
+
+259
+00:20:07,180 --> 00:20:11,680
+تصنيع الفيتامين D، والمهم جداً لحماية الجسم، والـ
+
+260
+00:20:11,680 --> 00:20:15,620
+sense receptors اللي بتخلينا على طول نحس، وبتعطينا
+
+261
+00:20:15,620 --> 00:20:20,340
+الـ flash على طول، أن أنا دعست مثلاً على مسمار، هنا
+
+262
+00:20:20,340 --> 00:20:27,060
+سخونة، هنا فيه دبوس، أنا حذائي ضيق، انجرحت، مسكت
+
+263
+00:20:27,060 --> 00:20:31,800
+السكين وأنا بقطع السلطة، وصار في عندي جروح، و
+
+264
+00:20:31,800 --> 00:20:37,170
+هكذا، نروح للـ skeletal system اللي هو الـ bone والـ
+
+265
+00:20:37,170 --> 00:20:41,510
+joints والـ cartilage، هي منظومة لحالها بتعطيني
+
+266
+00:20:41,510 --> 00:20:46,290
+الشكل الخارجي تبع الجسم، بتعطيني support كمان
+
+267
+00:20:46,290 --> 00:20:50,210
+protection، تساعد على الحركة، أنا بتحرك عن طريق ايش؟
+
+268
+00:20:50,210 --> 00:20:53,550
+تحريك العظام اللي بتحركها الـ musculoskeletal، الـ
+
+269
+00:20:53,550 --> 00:20:56,890
+muscular system اللي بدنا نتكلم عنه، بتعطيني blood
+
+270
+00:20:56,890 --> 00:21:00,810
+vessels، كمان بتعمل production للـ blood cells
+
+271
+00:21:00,810 --> 00:21:04,290
+الموجودة عن طريق الـ bone marrow، الـ mineral
+
+272
+00:21:04,290 --> 00:21:08,450
+storage، بتخزن، الـ skeletal system بيخزن كل الـ
+
+273
+00:21:08,450 --> 00:21:13,450
+minerals زي الكالسيوم والفوسفور في داخل العظام، أما
+
+274
+00:21:13,450 --> 00:21:16,490
+الـ muscular system اللي بيعطي الهيئة كده للجسم،
+
+275
+00:21:16,490 --> 00:21:21,250
+شكل الجسم، يعني احنا بنطلع على شخص بدين أو شخص
+
+276
+00:21:21,250 --> 00:21:24,830
+ضعيف، الشخص الضعيف هو كأنك بتشوفه هزيل وغير متحرك، الشخص
+
+277
+00:21:24,830 --> 00:21:28,170
+البدين بتشوفه، خاصة لو كان رياضي وفي عضلات،
+
+278
+00:21:28,170 --> 00:21:32,750
+بتشوف الشكل اللي عامل بيبين القوة، لأن
+
+279
+00:21:32,750 --> 00:21:37,610
+عضلاته قوية شديدة، أعطت الشكل تبع الجسم، العضلات هي
+
+280
+00:21:37,610 --> 00:21:42,990
+اللي بيسموها اللحمة، هي عبارة عن العضلات الهيكلية
+
+281
+00:21:42,990 --> 00:21:46,490
+الهيكلية، اللي associated with connective tissue،  سيتضمن
+
+282
+00:21:46,490 --> 00:21:50,730
+العضلات، الألياف اللي موجودة هنا، هذا النسيج كله
+
+283
+00:21:50,730 --> 00:21:54,990
+connective tissue، على أساس أنها توصل
+
+284
+00:21:54,990 --> 00:22:00,290
+هالمنظومة هذه مع بعضها، الـ functional locomotion،
+
+285
+00:22:00,290 --> 00:22:03,590
+الحركة والانتقال، الـ manipulation of the
+
+286
+00:22:03,590 --> 00:22:06,890
+environment، يعني أنا لما بدي أجي أزيح الكرسي،
+
+287
+00:22:06,890 --> 00:22:09,710
+بدي عضلات، بدي أزيح المكتب، بدي عضلات، بدي أحرك
+
+288
+00:22:09,710 --> 00:22:14,200
+الماوس، بدي عضلات، بدي أمشي، بدي عضلات، طبعاً احنا
+
+289
+00:22:14,200 --> 00:22:16,840
+بنطلع الـ facial expressions كلها اللي بيعمل العمل
+
+290
+00:22:16,840 --> 00:22:21,660
+الـ facial expressions، مكشرين، مبتسمين، كل الـ facial
+
+291
+00:22:21,660 --> 00:22:26,760
+expressions هذه بتقدّمها العضلات، طبعاً بتحافظ على الـ
+
+292
+00:22:26,760 --> 00:22:29,620
+position، احنا بنشوف ناس كتير محنّطين، في ناس بتلاقي
+
+293
+00:22:29,620 --> 00:22:33,520
+مستهترة بـ position، في ناس لأ، منضبطين والله، هم مرتّبين
+
+294
+00:22:33,520 --> 00:22:38,480
+وكمان الحركة عن طريق العضلات بتعطيني heat
+
+295
+00:22:38,480 --> 00:22:41,920
+production، عشان heat production بتدفّي، يعني احنا
+
+296
+00:22:41,920 --> 00:22:45,000
+بنلاحظ احنا أول ما بنبرد بنبدأ نفرك في أيدينا،
+
+297
+00:22:45,000 --> 00:22:48,560
+بنبدأ نمشي، بنبدأ نعمل رياضة عشان ايش؟ عشان نحرك
+
+298
+00:22:48,560 --> 00:22:53,480
+هالطاقة الكامنة اللي موجودة، وبالعربي ندفّي، والـ
+
+299
+00:22:53,480 --> 00:22:57,200
+circulatory system، فهو الـ cardiovascular system والـ
+
+300
+00:22:57,200 --> 00:22:59,980
+lymphatic system، ايش وظيفتهم؟ الـ transportation
+
+301
+00:22:59,980 --> 00:23:03,760
+يعني وسيلة المواصلات للدم، هي بتكون عبارة عن
+
+302
+00:23:03,760 --> 00:23:09,660
+القنوات اللي هي الموجودة في الـ vascular system والـ
+
+303
+00:23:09,660 --> 00:23:12,340
+lymphatic system، for the photomatransportation
+
+304
+00:23:12,340 --> 00:23:15,580
+of minerals within the body، بتوزّع المواد الغذائية
+
+305
+00:23:15,580 --> 00:23:20,620
+هذه على الـ body، وكمان to and from internal and
+
+306
+00:23:20,620 --> 00:23:23,980
+external environment، طيب احنا في عندنا الـ internal
+
+307
+00:23:23,980 --> 00:23:28,260
+environment وفي عندنا الـ external environment عن
+
+308
+00:23:28,260 --> 00:23:34,620
+طريقها، احنا ممكن ننظم جسم الإنسان، الـ
+
+309
+00:23:34,620 --> 00:23:42,540
+cardiovascular system، زي الـ heart والـ blood
+
+310
+00:23:42,540 --> 00:23:48,060
+vessels، function transportation of the blood، الدم
+
+311
+00:23:48,060 --> 00:23:52,460
+عادة بيكون فيه بيحمل أكسجين وثاني أكسيد الكربون،
+
+312
+00:23:54,420 --> 00:23:58,100
+احنا بناخد نفس وبناخد أكسجين وبنطلع وبنطلع ثاني
+
+313
+00:23:58,100 --> 00:24:02,000
+أكسيد الكربون، كيف بتصير هذه العملية؟ هنشرحها في
+
+314
+00:24:02,000 --> 00:24:06,560
+وقتها، الـ nutrients أو المواد الغذائية، الـ waste
+
+315
+00:24:06,560 --> 00:24:09,820
+product، كيف بتطلع كلها عن طريق الـ cardiovascular
+
+316
+00:24:09,820 --> 00:24:16,650
+system، الـ blood is composed of plasma and cells، الـ
+
+317
+00:24:16,650 --> 00:24:19,470
+lymphatic، طبعاً الـ lymphatic organs زي الـ spleen
+
+318
+00:24:19,470 --> 00:24:23,330
+والـ lymph nodes والـ thymus، lymphatic vessels
+
+319
+00:24:23,330 --> 00:24:27,950
+كلها بتربطها transportation of the lymph، lymph is
+
+320
+00:24:27,950 --> 00:24:34,570
+divided، derived، بيجي من الـ tissue، الـ fluid والـ
+
+321
+00:24:34,570 --> 00:24:39,730
+white، موجود فيه الـ white blood cells عشان تعزز
+
+322
+00:24:39,730 --> 00:24:43,590
+جهاز المناعة اللي احنا بنتكلم عنه اللي هو الـ
+
+323
+00:24:43,590 --> 00:24:48,640
+immune system، الـ component of immune system، الـ
+
+324
+00:24:48,640 --> 00:24:52,140
+immune organ، الـ bone marrow والـ thymus، الـ white
+
+325
+00:24:52,140 --> 00:24:55,400
+blood cells، الـ lymphocytes بنسميها، والـ macro
+
+326
+00:24:55,400 --> 00:25:01,140
+phages اللي هي الخلايا الأكّالة، هذه اللي بتساعد على
+
+327
+00:25:01,140 --> 00:25:08,140
+الـ phagocytosis، الـ function defense، دفاع، بس الدفاع
+
+328
+00:25:08,140 --> 00:25:11,960
+واحنا خط الدفاع الأول قلنا الـ skin، لكن الـ immune
+
+329
+00:25:11,960 --> 00:25:17,660
+system هو اللي بـيهاجم أي بكتيريا، أي فيروس، أي
+
+330
+00:25:17,660 --> 00:25:23,040
+شيء خارجي، نظام، المنظومة اللي هو الطبيعي أو الـ
+
+331
+00:25:23,040 --> 00:25:26,780
+normal اللي موجود في الجسم على طول بيعمل دفعات،
+
+332
+00:25:27,960 --> 00:25:31,920
+بتبدأ الغدة اللي هي thymus gland، تشغل على أساس
+
+333
+00:25:31,920 --> 00:25:39,460
+أنها تحفّز المناعة، و تهاجم كل الخلايا هذه اللي هاجمت
+
+334
+00:25:39,460 --> 00:25:42,780
+الجسم، وتقضي عليها، ولو صار خلل في جهاز المناعة
+
+335
+00:25:42,780 --> 00:25:47,600
+ممكن يصير يأكل بعضه، يعني يأكل الجيد والسيئ من
+
+336
+00:25:47,600 --> 00:25:51,720
+الخلايا، وهذا بيبقى شيء مرضي، أما الـ nervous system
+
+337
+00:25:51,720 --> 00:25:57,170
+وظيفته الـ control، في عندنا اثنين أساسياً من مكونات
+
+338
+00:25:57,170 --> 00:25:59,790
+الـ nervous system، عندنا الـ central nervous system والـ
+
+339
+00:25:59,790 --> 00:26:03,850
+peripheral، الـ central عبارة عن الـ spinal cord والـ
+
+340
+00:26:03,850 --> 00:26:07,730
+brain، والـ peripheral عبارة عن الـ nerve والـ
+
+341
+00:26:07,730 --> 00:26:14,010
+receptors اللي موجودة في الجسم، وظيفته control، fast
+
+342
+00:26:14,010 --> 00:26:21,370
+hard wired، أول حاجة أنا بتعرّض لها، إجا حد بده يوقعني،
+
+343
+00:26:21,370 --> 00:26:24,830
+على طول أنا بنتبه، بمسك إيده أو برفع إيدي بهذا
+
+344
+00:26:24,830 --> 00:26:28,610
+الشكل، حطيت إيدي وحمّلت... مسكت الـ microwave مثلاً
+
+345
+00:26:28,610 --> 00:26:33,480
+طلعت كوباية أو صحن سخن، برميه، دعست على مسمار، برفع
+
+346
+00:26:33,480 --> 00:26:38,280
+رجلي، اتعرضت لخطر معين، بخاف أو بشد على جسمي وهكذا،
+
+347
+00:26:38,280 --> 00:26:42,980
+Respond to external and internal environments، طبعاً
+
+348
+00:26:42,980 --> 00:26:46,040
+بيجيه الإحساس في الـ external environment، طب كيف بي
+
+349
+00:26:46,040 --> 00:26:48,380
+respond to the external environment؟ بيجيه الإحساس،
+
+350
+00:26:48,380 --> 00:26:51,340
+أنا لقيتها قاعدة في التكييف، حسيت الجو بارد، طلعت
+
+351
+00:26:51,340 --> 00:26:56,030
+برا، بحسه حار، والله الجو بارد كثير، تلج، بحس هذا
+
+352
+00:26:56,030 --> 00:26:58,990
+إحساس اجى من  امسكت شيء ساخن، هذا external
+
+353
+00:26:58,990 --> 00:27:03,310
+environment، بتجي إحساس لجسمي، أما الـ endocrine
+
+354
+00:27:03,310 --> 00:27:08,830
+system، طبعاً المسؤول عن الـ control السريع اللي هو الـ
+
+355
+00:27:08,830 --> 00:27:11,650
+nervous system، على الـ control البطيء اللي هو الـ
+
+356
+00:27:11,650 --> 00:27:14,550
+endocrine system، اللي هو عبارة عن الـ gland to
+
+357
+00:27:14,550 --> 00:27:18,990
+secret that secretes hormones، الـ hormones هذه هي
+
+358
+00:27:18,990 --> 00:27:23,070
+اللي بتنظم الجسم، الغدد المختلفة، الـ pituitary،
+
+359
+00:27:23,070 --> 00:27:27,550
+الـ pancreas، الـ thyroid اللي بيسموه الغدد الدرقية، والـ
+
+360
+00:27:27,550 --> 00:27:31,750
+الدرقية، والـ pancreas اللي بيفرز لي هرمون الأنسولين
+
+361
+00:27:31,750 --> 00:27:36,020
+وهكذا، أما الـ function هي الـ slow chemicals، اللي
+
+362
+00:27:36,020 --> 00:27:39,160
+هي ردود فعل بطيئة، احنا بنأخذها الـ nervous
+
+363
+00:27:39,160 --> 00:27:42,620
+system، أما ردود الفعل البطيئة اللي هي بتعمل
+
+364
+00:27:42,620 --> 00:27:47,640
+تنظيم لبيئة الجسم، أو بتحافظ على الـ homogenous أو
+
+365
+00:27:47,640 --> 00:27:53,060
+الـ homeostasis، والـ homeostasis هو عبارة عن الـ
+
+366
+00:27:53,060 --> 00:27:56,960
+endocrine system regulates، الـ process such as
+
+367
+00:27:56,960 --> 00:28:00,920
+growth، reproductive and nutrient uses.
+
+368
+00:28:02,740 --> 00:28:05,420
+Respiratory System هو عبارة عن الـ lung وكل الـ
+
+369
+00:28:05,420 --> 00:28:08,760
+tubes زي القصبة الهوائية، والـ bronchi وغيره، والـ larynx
+
+370
+00:28:08,760 --> 00:28:12,080
+اللي هي الـ vocal cord، اللي هي عبارة عن الحنجرة
+
+371
+00:28:12,080 --> 00:28:16,500
+اللي موجودة فيها الـ Voice Box اللي بيخلّينا نقدر
+
+372
+00:28:16,500 --> 00:28:21,710
+نصدر هذه الأصوات، طبعاً ايش؟ وظيفة الـ lungs اللي هي
+
+373
+00:28:21,710 --> 00:28:25,190
+exchange of respiratory gases، الأكسجين، يعني احنا
+
+374
+00:28:25,190 --> 00:28:30,350
+بناخد نفس، بناخد الأكسجين وبنطلع ثاني أكسيد
+
+375
+00:28:30,350 --> 00:28:33,930
+الدم بيمر، بياخد الأكسجين من الـ alveoli وبيعطيها
+
+376
+00:28:33,930 --> 00:28:38,300
+ثاني أكسيد الكربون، هذه عملية الشهيق، أما الزفير
+
+377
+00:28:38,300 --> 00:28:41,680
+فإحنا بنطلع ثاني أكسيد الـ carbon، الـ voice
+
+378
+00:28:41,680 --> 00:28:44,400
+production، إحنا لما بنتكلم لازم يكون فيه يعني
+
+379
+00:28:44,400 --> 00:28:47,740
+نلاحظ أن الناس بتبقى عاملة تركز، ثم هنا في الفتحة
+
+380
+00:28:47,740 --> 00:28:51,580
+في القصبة الهوائية ما بيطلع صوتها، لأن الهواء
+
+381
+00:28:51,580 --> 00:28:58,090
+وترددات الهواء ما وصلت للأحبال الصوتية، الـ digestive
+
+382
+00:28:58,090 --> 00:29:01,870
+system هو الجهاز الهضمي، فيه الـ alimentary canal زي
+
+383
+00:29:01,870 --> 00:29:05,010
+الـ mouth، الـ pharynx، الـ oesophagus، في عندنا قناة
+
+384
+00:29:05,010 --> 00:29:09,110
+بنسميها القناة الهضمية، وفي عندنا اللي هي ملحقات
+
+385
+00:29:09,110 --> 00:29:13,030
+الجهاز الهضمي زي الكبد، الـ liver، saliva gland، الـ
+
+386
+00:29:13,030 --> 00:29:16,450
+pancreas، هذه بنسميها، الـ spleen، كلها ملحقات
+
+387
+00:29:16,450 --> 00:29:20,270
+الجهاز الهضمي، وthe feta break down the food into
+
+388
+00:29:20,270 --> 00:29:25,230
+smaller objects، عشان نقدر احنا نعمله absorption و
+
+389
+00:29:25,230 --> 00:29:30,910
+نستفيد من المواد الغذائية اللي احنا بناخدها أثناء
+
+390
+00:29:30,910 --> 00:29:34,610
+من الطعام اللي احنا بناخده والشراب، الـ absorption
+
+391
+00:29:34,610 --> 00:29:38,430
+عشان تروح للـ blood وتروح على أجهزة في الجسم
+
+392
+00:29:38,430 --> 00:29:43,770
+المختلفة، وكمان حتى نتخلص من الـ waste product، يعني
+
+393
+00:29:43,770 --> 00:29:47,330
+متخيلين أنه احنا لو
\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..e20b905b2cba457a323e21460dfe1e2c37d6fc55
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU_postprocess.srt
@@ -0,0 +1,1692 @@
+1
+00:00:05,870 --> 00:00:09,630
+بسم الله الرحمن الرحيم الصلاة والسلام علي سيدنا
+
+2
+00:00:09,630 --> 00:00:13,730
+محمد سيد المرسلين محاضرتنا الأولى في مساق ال
+
+3
+00:00:13,730 --> 00:00:18,110
+anatomy للفصل الصيفي ان شاء الله بنكون معاكوا أنا
+
+4
+00:00:18,110 --> 00:00:21,890
+دكتورة علي القشاوي قصية علاج طبيعي و تأهيل مدير
+
+5
+00:00:21,890 --> 00:00:25,010
+دائرة التأهيل والعلاج الطبيعي في وزارة الصحة
+
+6
+00:00:25,010 --> 00:00:30,550
+محاضرة بالجامعة الإسلامية بقسم العلاج الطبيعي
+
+7
+00:00:30,550 --> 00:00:37,160
+لكلية العلوم الصحيةانشاء الله طبعا يكون محادرتنا
+
+8
+00:00:37,160 --> 00:00:41,120
+لليوم و المحادرات اللي جاية من المحادرات اللي نكون
+
+9
+00:00:41,120 --> 00:00:46,360
+قيمة لإنها مساقة تشريح من المساقات الأساسية في ..
+
+10
+00:00:46,360 --> 00:00:51,360
+لأي متخصص في مجال العلوم الصحية، لازم نبقى نعرف
+
+11
+00:00:51,360 --> 00:00:55,180
+على الأقل تركيبة الجسم هذا اللي احنا بنتعامل معاه
+
+12
+00:00:55,260 --> 00:00:59,540
+أنتوا متخصصين في مجال العلوم الصحية و طبعا أنا
+
+13
+00:00:59,540 --> 00:01:02,680
+بتمنى لكم التوفيه لإن أنا بعرف أنه أكيد هيكون معمط
+
+14
+00:01:02,680 --> 00:01:07,580
+الله بطالبات من كلية الطب و العلوم الصحية و هدولة
+
+15
+00:01:07,580 --> 00:01:11,640
+أكيد يعني هيكونوا في يوم الأيام خرجين بيرفعوا
+
+16
+00:01:11,640 --> 00:01:15,840
+الراس أكيد هيتعاملوا مع هذا الإنسان و هيكونوا
+
+17
+00:01:15,840 --> 00:01:21,900
+مثابت يعني مقدمين خدمة صحية لهذا الشخص و .. و أكيد
+
+18
+00:01:21,900 --> 00:01:28,000
+منهم هيكونواناس قادرين على تحسين جودة حياة الإنسان
+
+19
+00:01:28,000 --> 00:01:31,660
+و كذلك على نسميه ال life saving لكي يحافظوا على
+
+20
+00:01:31,660 --> 00:01:39,140
+حياة هذا الإنسان و منع الإعاقة و خليني أقول على
+
+21
+00:01:40,290 --> 00:01:44,270
+قدراته لنحافظ على قدراته الصحية حتى يكون إنسان
+
+22
+00:01:44,270 --> 00:01:47,530
+مستقل عشان هيك لازم يكون فيه علنا معرفة بعرف انكم
+
+23
+00:01:47,530 --> 00:01:50,070
+انتوا من تخصيصات مختلفة منها الطب منها العلاج
+
+24
+00:01:50,070 --> 00:01:55,210
+الطبيعي منها البصريات منها التحاليل الطبية طبعا
+
+25
+00:01:55,210 --> 00:02:00,680
+نحاول أن نكون يعني مش هنخل في قمطالتشريح لأن أكيد
+
+26
+00:02:00,680 --> 00:02:04,580
+انتوا هذا المصاد سيعاد انكوا كل واحد حسب التخصص
+
+27
+00:02:04,580 --> 00:02:09,840
+اللي هو بده يروح عليه خلنا نتعرف في البداية على
+
+28
+00:02:09,840 --> 00:02:16,360
+التعريف ال anatomy ال anatomy هو علم التشريح طيب
+
+29
+00:02:16,360 --> 00:02:20,860
+هذه الكلمة من وين إجت؟ إجت هي كلمة إغريقية أو
+
+30
+00:02:20,860 --> 00:02:28,600
+Greek بقنها to cut up انها نقطع او ن dissectthe
+
+31
+00:02:28,600 --> 00:02:31,560
+science that deal with the structure of the body
+
+32
+00:02:31,560 --> 00:02:34,840
+طول عمرنا بنسمع عن حاجة اسمها anatomy و حاجة اسمها
+
+33
+00:02:34,840 --> 00:02:38,400
+physiology ممكن أنا شخصيا لما درست درستهم اتنين مع
+
+34
+00:02:38,400 --> 00:02:42,640
+بعض في كتاب اسمه anatomy and physiology كان سؤال
+
+35
+00:02:42,640 --> 00:02:45,600
+بت الفصل بين ال anatomy و ال physiology لأن انت ال
+
+36
+00:02:45,600 --> 00:02:48,980
+anatomy بيعتني بال structure تبع الأشياء أما ال
+
+37
+00:02:48,980 --> 00:02:52,060
+physiology بيعتني بالوظيفة يعني عشان لازم تعرف
+
+38
+00:02:52,060 --> 00:02:57,410
+الوظيفة لازم تعرف ال structureمافيش إمكانية صعوبة
+
+39
+00:02:57,410 --> 00:03:01,230
+الفصل ما بين هدول إلا إنه في بعض المثاقات بتفصل ما
+
+40
+00:03:01,230 --> 00:03:04,690
+بينهم زي المثاق اللي احنا هتكلم بس عن ال structure
+
+41
+00:03:04,690 --> 00:03:09,150
+تبع ال body و أجزاء ال body المختلفة طب ماهيش
+
+42
+00:03:09,150 --> 00:03:12,710
+أنواع ال anatomy؟ في عندنا ال gross anatomy اللي
+
+43
+00:03:12,710 --> 00:03:16,650
+هو بيعتني بالمظهرالخارجى او اللى ما يرعى بالعين
+
+44
+00:03:16,650 --> 00:03:20,750
+المجردة فيه ال microscopic anatomy اللى ما بنقدرش
+
+45
+00:03:20,750 --> 00:03:24,810
+نشوفه بالعين المجردة بنشوفه تحت ال maestroscope ال
+
+46
+00:03:24,810 --> 00:03:29,170
+developmental بنشوف التطور علم التطور الأشخاص أو
+
+47
+00:03:29,170 --> 00:03:33,330
+الأفراد من ال embryology لحد ما يصير الشخص كبير
+
+48
+00:03:33,330 --> 00:03:36,990
+بالسن وفيه ال comparative anatomy اللى بيقارن
+
+49
+00:03:36,990 --> 00:03:41,490
+الكائنات مع بعضها او الفقريات مع بعضها لو تكلمنا
+
+50
+00:03:41,490 --> 00:03:46,620
+عن ال human beingsطب إيش هو ال gross anatomy؟ ال
+
+51
+00:03:46,620 --> 00:03:51,240
+gross anatomy هو العلم اللي بيعتني بال structure
+
+52
+00:03:51,240 --> 00:03:55,060
+with naked eyes، يعني أنا بعيني بقدر أشوف الشخص
+
+53
+00:03:55,060 --> 00:04:00,050
+هذا، بقدر أقول الشخص قداني، هذا فيه headفي
+
+54
+00:04:00,050 --> 00:04:02,910
+shoulders، في upper limbs، في lower limbs، في
+
+55
+00:04:02,910 --> 00:04:09,770
+trunk، في abdomen، هذا كله بشوفه طيب لو فتحت أنا
+
+56
+00:04:09,770 --> 00:04:14,910
+ومسكت مشرط و جيت على جثة أو ومسكت skeleton بقدر
+
+57
+00:04:14,910 --> 00:04:21,330
+أقول والله هذه العدمة هي ال femur، هذه ال scapula،
+
+58
+00:04:21,330 --> 00:04:25,930
+بشوفها بعيني، مامحتاج انا أحطها under microscopeكل
+
+59
+00:04:25,930 --> 00:04:30,630
+هذه الأشياء هنتعرف عليها لما نجي نستخدم أو نتعرف
+
+60
+00:04:30,630 --> 00:04:35,910
+على ال region by region فبنتكلم عنه أنواعه طيب ال
+
+61
+00:04:35,910 --> 00:04:38,870
+gross anatomy مش بتتكلم regionally يعني بيستخدم ال
+
+62
+00:04:38,870 --> 00:04:40,890
+upper part of the body lower part of the
+
+63
+00:04:40,890 --> 00:04:43,610
+extremities ال appendicular system اللي هو ال
+
+64
+00:04:43,610 --> 00:04:49,170
+trunk و ال head ال axial .. sorry ال axial اللي هو
+
+65
+00:04:49,170 --> 00:04:52,510
+ال head و ال trunk ال appendicular هيالاطراف ال
+
+66
+00:04:52,510 --> 00:04:55,770
+regional لكن ال system يستخدم يتكلم عن ال
+
+67
+00:04:55,770 --> 00:04:59,150
+respiratory system ال cardiovascular system عن ال
+
+68
+00:04:59,150 --> 00:05:02,430
+endocrine
+
+69
+00:05:02,430 --> 00:05:06,210
+system ال integumentary system كل ال system في 11
+
+70
+00:05:06,210 --> 00:05:12,050
+system of the body ممكن يتدرسوا one by oneالـ
+
+71
+00:05:12,050 --> 00:05:15,810
+Gastrointestinal وغيره هنشوفهم كما نشوف أما ال
+
+72
+00:05:15,810 --> 00:05:19,610
+microscopic فهو وين؟ هذا بيعتمد بالأشياء اللي احنا
+
+73
+00:05:19,610 --> 00:05:22,930
+مابنقدر نشوفها بالعين المجردة نشوفها under
+
+74
+00:05:22,930 --> 00:05:28,250
+microscope ال cytology و ال histology و ال
+
+75
+00:05:28,250 --> 00:05:33,470
+organologyالـ cytology بيشوف الخلية و بيحاول يدرس
+
+76
+00:05:33,470 --> 00:05:37,490
+هذه الخلية إيش خصائص الخلية هذه، فيها nucleus، مش
+
+77
+00:05:37,490 --> 00:05:40,270
+فيها nucleus، فيها cytoplasm، فيها .. و كل هذه
+
+78
+00:05:40,270 --> 00:05:43,610
+الأشياء مين اللي بيشوفها علم الـ cytology under
+
+79
+00:05:43,610 --> 00:05:47,330
+microscopistsالتيلوجي بتتكلم عن ال tissue نفسها،
+
+80
+00:05:47,330 --> 00:05:51,390
+هنقول إيه؟ إن السل مكون أساسي مثلا لل organ،
+
+81
+00:05:51,390 --> 00:05:54,970
+مجموعة من السل بتتحد، بتكون إلها خواص معينة بتعمل
+
+82
+00:05:54,970 --> 00:05:58,530
+tissue، خواص ال tissue هذه اللي هي لما بتتركب مع
+
+83
+00:05:58,530 --> 00:06:01,990
+بعضها أو بتتحد مع بعضها، بتتكون لي حاجة اسمها
+
+84
+00:06:01,990 --> 00:06:08,270
+organ، فهن كل واحد من هذه المكونات ممكن تندرس
+
+85
+00:06:08,270 --> 00:06:13,810
+under microscopeأما الـ Developmental فهو بيقتنع
+
+86
+00:06:13,810 --> 00:06:18,490
+بالـ anatomical changes during ال life cycle طب ال
+
+87
+00:06:18,490 --> 00:06:22,410
+life cycle هذه بتبدأ من ال emperiology وبعدين
+
+88
+00:06:22,410 --> 00:06:28,290
+بتبدأ التطور التطور الجنين من اتحاد ال spare مع ال
+
+89
+00:06:28,290 --> 00:06:34,050
+organ لحد ما يتكون الجنين في يوم ما يصير فيه قيلو
+
+90
+00:06:34,050 --> 00:06:37,230
+ولادة فهذا بيسموه emperiology أما ال postnatal
+
+91
+00:06:37,230 --> 00:06:43,670
+developmentاللي يبدأ من عمر واحد لنهاية العمر سواء
+
+92
+00:06:43,670 --> 00:06:48,850
+إما تبدأ العمر لأيام، لشهور، لسنوات أو سنوات عديدة
+
+93
+00:06:48,850 --> 00:06:54,530
+و لو الإنسان وصل فيه لعمر متقدم بالسن فهذا بيسمى
+
+94
+00:06:54,530 --> 00:06:58,470
+anatomical difference طبعا في فرق بين عدمة ال baby
+
+95
+00:06:58,470 --> 00:07:01,790
+اللي هي معظمها cartilage مع عدمة ال adolescence
+
+96
+00:07:01,790 --> 00:07:06,790
+اللي هي مبنية هنا في سئلها ossificationمعظمة الـ
+
+97
+00:07:06,790 --> 00:07:12,710
+Old Ages اللي هي osteoporotic فهنا هذا الدراسة
+
+98
+00:07:12,710 --> 00:07:19,380
+بتصير معمقة على جميع الخلاياأما ال comparative
+
+99
+00:07:19,380 --> 00:07:22,420
+anatomy اللي هو بيقارن الفقريات بعضها ال
+
+100
+00:07:22,420 --> 00:07:25,400
+comparison of the structure between organisms يعني
+
+101
+00:07:25,400 --> 00:07:31,280
+إحنا شايفين hand ل human و ل dog و ل bird كل واحدة
+
+102
+00:07:31,280 --> 00:07:35,940
+هادي إيد و هادي إيد و هادي إيد كل واحدة إلها وظيفة
+
+103
+00:07:36,600 --> 00:07:42,120
+هي إيد حقيقي لكن هي الوظيفة اللي بتقدرها حسب الشخص
+
+104
+00:07:42,120 --> 00:07:48,140
+أو الحائق الكائن اللي هو بتتبعله و بنشوف فيه تشابه
+
+105
+00:07:48,140 --> 00:07:53,040
+أحيانا بيكون أن معظمها فيها عضمة الهيوميراس وبعدين
+
+106
+00:07:53,040 --> 00:07:59,820
+عضمتين تحت وهكذا يبقى هي ال comparison between
+
+107
+00:07:59,820 --> 00:08:04,760
+destruction among vertebrae classes أو الفقرية
+
+108
+00:08:04,760 --> 00:08:13,420
+تمام؟هو العلم الخاص وظيفة
+
+109
+00:08:13,420 --> 00:08:18,580
+الأعضاء، إيش هي وظيفة الأعضاء؟ هو صحيح جدا أن أقول
+
+110
+00:08:18,580 --> 00:08:24,280
+أن هناك فصل بين ال structure و بين ال function،
+
+111
+00:08:24,280 --> 00:08:29,910
+العين في وظيفتها المتشورطيب، لازم أعرف إيش هي
+
+112
+00:08:29,910 --> 00:08:34,370
+العين، إيش تركيبة العين، كيف بتحقيق عملية الرؤية،
+
+113
+00:08:34,370 --> 00:08:38,850
+طبعا؟ الإيد وظيفتها إمكانية الوصول للأشياء، طب كيف
+
+114
+00:08:38,850 --> 00:08:42,930
+لازم أعرف الـ structure؟ هي كلها عضمة واحدة، هي
+
+115
+00:08:42,930 --> 00:08:46,470
+مجموعة من الإضام والمفاصل، طب في عضلات، طب العضلات
+
+116
+00:08:46,470 --> 00:08:49,700
+هذه إيش بتعمل؟وظيفة الله طب انا لازم اعرف ان هذه
+
+117
+00:08:49,700 --> 00:08:52,100
+العضلة واش تركبتها واش طولها وان origin وان
+
+118
+00:08:52,100 --> 00:08:55,060
+insertion بعد هيك ال function تبعيتها كيف انا بدي
+
+119
+00:08:55,060 --> 00:08:57,760
+اعرفها اعرفها عن طريق الفيسيولوجيا او علم
+
+120
+00:08:57,760 --> 00:09:00,220
+الفيسيولوجيا طب العضلة هذه ايش بتفرق عن العضلة هذه
+
+121
+00:09:00,220 --> 00:09:03,200
+عضلة ربعية و هذه عضلة تنائية عضلة طويلة هذي عضلة
+
+122
+00:09:03,200 --> 00:09:06,360
+قصيرة هذي شكلها عاملة زي الريشة هذي شكلها طب و
+
+123
+00:09:06,360 --> 00:09:10,620
+بعدين كل واحدة بتقدم وظيفة تتناسب معاه يبقى انا
+
+124
+00:09:10,620 --> 00:09:14,040
+لازم ابقى عارفة ال anatomy عشان انا اقدر ادرس
+
+125
+00:09:14,040 --> 00:09:15,580
+الفيسيولوجيا
+
+126
+00:09:18,440 --> 00:09:21,280
+طيب نشوف الـ structural level of the organization
+
+127
+00:09:22,370 --> 00:09:29,690
+الحين بتتكلم عن الذرة والجزاء وكيف بتتكون هذا ال
+
+128
+00:09:29,690 --> 00:09:34,510
+body كامل تبدأ من أشياء صغيرة جدا تتحد مع بعضها
+
+129
+00:09:34,510 --> 00:09:38,010
+تصير أكبر شوية تتحد مع بعضها تصير أكبر أكتر تتحد
+
+130
+00:09:38,010 --> 00:09:41,870
+مع بعضها تصير مجموعة من ال من ال من ال cells اللي
+
+131
+00:09:41,870 --> 00:09:45,130
+هي متشابهة بتعمل ال tissue مجموعة من ال tissues
+
+132
+00:09:45,130 --> 00:09:48,970
+متشابهة بتعمل ال organ مجموعة من ال organs بتعمل
+
+133
+00:09:48,970 --> 00:09:55,500
+الالـ body هذا أو ال systems ال systems كلها
+
+134
+00:09:55,500 --> 00:10:02,420
+بتعملي ال body و هنشوفهم واحدة واحدة ال atom زي ال
+
+135
+00:10:02,420 --> 00:10:08,120
+carbon ال hydrogen ال oxygen ال atom the smallest
+
+136
+00:10:08,120 --> 00:10:13,480
+the smallest أصغر واحدة particle of an element
+
+137
+00:10:13,480 --> 00:10:19,040
+atom combinedwith or react مع other atom اتنين اتم
+
+138
+00:10:19,040 --> 00:10:24,140
+او اكثر بيعمللي حاجة اسمها molecule الموليكول اللي
+
+139
+00:10:24,140 --> 00:10:27,620
+هتطلعني من ال carbon لحاله صار عندي carbon dioxide
+
+140
+00:10:27,620 --> 00:10:32,480
+تاني اكسيد الكربون صار عندي H2O اللي هو ال water
+
+141
+00:10:32,480 --> 00:10:36,600
+تمام؟ هذه ال molecules defined as particle
+
+142
+00:10:36,600 --> 00:10:41,130
+composed of two or morejoined atom يعني فى عندي
+
+143
+00:10:41,130 --> 00:10:45,410
+ذرتين اتحدوا فعمله منى عمله الجزاء اللى هو صار اشى
+
+144
+00:10:45,410 --> 00:10:51,750
+تانى مختلف الهيدروجين لحاله مع الكرباء مع ال .. مع
+
+145
+00:10:51,750 --> 00:10:55,810
+الاكسوجين كان هذا لحاله و هذا لحاله غازين مختلفين
+
+146
+00:10:55,810 --> 00:11:02,130
+لما اتحدوا مع بعض اعمله مية فصار فى عنديجزائي، طيب
+
+147
+00:11:02,130 --> 00:11:05,050
+الجزائي لو كان كبري شوية زي الـ carbon،
+
+148
+00:11:05,050 --> 00:11:08,230
+الـdehydrate أو الـ lipid أو البروتين، اللي هو
+
+149
+00:11:08,230 --> 00:11:15,770
+البروتينات والدهون، كل هذهعبارة عن ايش؟ Large
+
+150
+00:11:15,770 --> 00:11:20,810
+molecule، موليكول بس ايش، اكبير، ال macro
+
+151
+00:11:20,810 --> 00:11:24,610
+molecules combined with others، macro molecules،
+
+152
+00:11:24,610 --> 00:11:27,270
+كلهم بتحضر مع بعض عشان يعملول ال organelle، ال
+
+153
+00:11:27,270 --> 00:11:31,740
+organelle أقل من الcellالتي زي الـ cell membrane
+
+154
+00:11:31,740 --> 00:11:36,040
+للميوكلياس الريبوسومس هي defined as the small
+
+155
+00:11:36,040 --> 00:11:40,300
+organ of the cell organelle هي اسم ال organ of the
+
+156
+00:11:40,300 --> 00:11:43,600
+cell هاي ال cell which perform a particular
+
+157
+00:11:43,600 --> 00:11:48,320
+function ال organelle بتحدوا مع بعض فبيعملولي حاجة
+
+158
+00:11:48,320 --> 00:11:53,660
+اسمهاالـ Cell، الـ Cell هذه بتبدأ تتغير أو بتبدأ
+
+159
+00:11:53,660 --> 00:11:59,880
+تاخد نمط معين أو شكل معين أو خصائص معينة عشان تقدي
+
+160
+00:11:59,880 --> 00:12:04,760
+وظيفة اتحدت مع بعضها بتعمل لـ tissue في بعض الـ
+
+161
+00:12:04,760 --> 00:12:09,960
+cells المستقلة بذاتها زي الـ RBCs أو الـ Red Blood
+
+162
+00:12:09,960 --> 00:12:14,090
+CellsDefined as the basic unit of the structure
+
+163
+00:12:14,090 --> 00:12:18,530
+and function of living organisms هي الخلية
+
+164
+00:12:18,530 --> 00:12:27,480
+الأساسية ال basic unit اللي بتعمل بتحددش شكلتعمل
+
+165
+00:12:27,480 --> 00:12:33,500
+شكل عشان تحدد هي وين، هي خلية عصبية ولا خلية ..
+
+166
+00:12:33,500 --> 00:12:40,600
+خلية قلب ولا هي خلية اتحاد هيعمللي ال muscle أو
+
+167
+00:12:40,600 --> 00:12:47,630
+خلية هذه اتحاد هيعمللي ال ball أو غيريبقى بعض ال
+
+168
+00:12:47,630 --> 00:12:52,290
+cells have all the machinery that they need to
+
+169
+00:12:52,290 --> 00:12:59,170
+live يعني بتعيش مستقلة زي ال RBCs هي لها وظيفة
+
+170
+00:12:59,170 --> 00:13:06,230
+مستقلة ان هي بتحمل ال oxygen او transport ال
+
+171
+00:13:06,230 --> 00:13:11,820
+oxygenطبعا مجموعة من ال cells طبعا نقول مجموعة من
+
+172
+00:13:11,820 --> 00:13:16,260
+ال cells زي ال RBCs و ال white blood cells و ال
+
+173
+00:13:16,260 --> 00:13:21,560
+plasma بيكوّل الدم مع بعض مش لحالها ال RBCs طيب لو
+
+174
+00:13:21,560 --> 00:13:25,400
+اتكلمنا على مجموعة من ال neurons اللي هي ال cell
+
+175
+00:13:25,400 --> 00:13:29,800
+الخاصة بالجهاز العصبي فهي بتهتعمل مجموعة من ال
+
+176
+00:13:29,800 --> 00:13:32,740
+cells بتعمل ال tissue الخاصة بالجهاز العصبي اللي
+
+177
+00:13:32,740 --> 00:13:38,240
+بعدين بتهتعمل الجهاز العصبي المتكاملالخلايا زي الـ
+
+178
+00:13:38,240 --> 00:13:41,020
+epithelial و ال connective tissue و ال muscle و ال
+
+179
+00:13:41,020 --> 00:13:45,420
+nervous cells defined as a group of similar cells
+
+180
+00:13:45,420 --> 00:13:48,460
+that perform specialized function
+
+181
+00:13:51,620 --> 00:13:55,500
+العضلية تتحد مع بعض بتعمل ال tissue تبع العضلة
+
+182
+00:13:55,500 --> 00:14:01,360
+اللي هي بتشكل الحركة المسؤولة عن الحركة وها كذا
+
+183
+00:14:01,360 --> 00:14:05,320
+الخلايا العصبية مع بعض بتتحد بتعمل الجهاز العصبي
+
+184
+00:14:05,320 --> 00:14:11,540
+اللي هو المسؤول عن ال control تبع الجسم أو ال body
+
+185
+00:14:11,540 --> 00:14:17,640
+كله فالمجموعة السلها دي لما بتتحد بتعملي organ زي
+
+186
+00:14:17,640 --> 00:14:24,010
+ال skinخلايا ال skin غير عن خلايا حضارة القلب غير
+
+187
+00:14:24,010 --> 00:14:27,050
+عن الخلايا ال nervous system اللي بتكون ال brain
+
+188
+00:14:27,050 --> 00:14:31,570
+يبقى an organ is defined as the structure consists
+
+189
+00:14:31,570 --> 00:14:35,990
+of a group of tissue that perform specialized
+
+190
+00:14:35,990 --> 00:14:42,530
+functionطيب two organs لو اتكلمنا مثلا عن ال
+
+191
+00:14:42,530 --> 00:14:47,070
+gastro-intestinal بتبقى بالقناة الهضمية بيروح على
+
+192
+00:14:47,070 --> 00:14:51,190
+المعدة بيروح على ال intestines وبعدها بتصير عملية
+
+193
+00:14:51,190 --> 00:14:55,910
+الإخراج مجموعة من ال organs هذه عملت ال system
+
+194
+00:14:55,910 --> 00:15:01,170
+اللي هو اسمه الجهازSystem زي الـ Integumentary
+
+195
+00:15:01,170 --> 00:15:06,630
+اللي هو جهاز الخارجي أو الجلد ال cardiovascular
+
+196
+00:15:06,630 --> 00:15:10,790
+وغير واحنا بنعرف ال cardiovascular في عندنا القلب
+
+197
+00:15:10,790 --> 00:15:14,390
+و الدورة الدموية الصغرى و الدورة الدموية الكبرى
+
+198
+00:15:14,390 --> 00:15:17,910
+القلب بيوديالدم عن طريق دور دمائه الصغر على
+
+199
+00:15:17,910 --> 00:15:22,690
+الرئتين و بودد الدم عن طريق الأورطة على جميع أجزاء
+
+200
+00:15:22,690 --> 00:15:25,830
+الجسم و برجع بجيب الدم عن طريق ال infero superior
+
+201
+00:15:25,830 --> 00:15:29,410
+vena cava و عن طريق الأوراد الرئاوية الأربعة و
+
+202
+00:15:29,410 --> 00:15:32,830
+بصير في عندنا دم مأكثر و دم غير مأكثر و هذه كلها
+
+203
+00:15:32,830 --> 00:15:37,230
+اسمها system اسمه cardiovascular system احنا
+
+204
+00:15:37,230 --> 00:15:43,320
+تقريبا عندناorgan system موجودين في ال body هدول
+
+205
+00:15:43,320 --> 00:15:46,840
+ال 11 system مع بعض بيكونوا الهيئة اللي احنا
+
+206
+00:15:46,840 --> 00:15:52,980
+شايفينها هذه من الجسد وما خلينا نقول العظام اللي
+
+207
+00:15:52,980 --> 00:15:57,280
+بتاكسوها اللحم اللي بياكسوها الجلد ال internal
+
+208
+00:15:57,280 --> 00:16:01,100
+organs كلها اللي بتنظم عملية اللي في عندنا كبد وفي
+
+209
+00:16:01,100 --> 00:16:04,460
+عندنا طحال وفي عندنا في عندنا قناهادية وملاحقة
+
+210
+00:16:04,460 --> 00:16:10,810
+قناهادمية في عندنا رئتين وفي عندنا تراكياكل هذه ال
+
+211
+00:16:10,810 --> 00:16:14,930
+systems موجودة في ال body عشان تكون الهيئة العامة
+
+212
+00:16:14,930 --> 00:16:17,850
+اللي احنا بنشوفها هذه و بتقدي لل function اللي
+
+213
+00:16:17,850 --> 00:16:24,170
+احنا بنقديها هذا شخص متكامل انسان human being طبعا
+
+214
+00:16:24,170 --> 00:16:28,190
+فيالتقسيمة تانية عموما نتكلم أنه كل مجموعة من
+
+215
+00:16:28,190 --> 00:16:32,370
+الناس بيعملوا مجتمع population و ال population
+
+216
+00:16:32,370 --> 00:16:35,910
+هدول بيعملوا مجتمع و بيعملوا نظام اقتصادي و
+
+217
+00:16:35,910 --> 00:16:39,810
+بيعملوا نظام .. هذه كلها لما مجموعة الأفراد يعني
+
+218
+00:16:39,810 --> 00:16:43,370
+لإن إحنا في الشرق الأوسط إحنا بيسمونا شرقيين إحنا
+
+219
+00:16:43,370 --> 00:16:47,650
+مسلمين و هدولة مسيحية إحنا اليهود مثلا كل
+
+220
+00:16:47,650 --> 00:16:51,890
+المجموعات هذه بتتشابه في الصفات و بتكون عرق أو
+
+221
+00:16:51,890 --> 00:16:55,870
+بتكون community أو بتكوننظام اقتصادي زي الاتحاد
+
+222
+00:16:55,870 --> 00:17:01,610
+الأوروبي زي الامريكا ال united states ال united
+
+223
+00:17:01,610 --> 00:17:10,150
+emirates كلها هذه أنظمة اقتصادية و دول طيب هاي
+
+224
+00:17:10,150 --> 00:17:15,210
+الرسم التوضيحي ببسط العملية بقولنا كيف بتبدأ من
+
+225
+00:17:15,210 --> 00:17:19,650
+اتحادات ال atoms عشان نروح ل ال molecules مجموعة
+
+226
+00:17:19,650 --> 00:17:25,580
+ال molecules ايش بتعمل هي بتكون ل ال muscleبتكون
+
+227
+00:17:25,580 --> 00:17:32,100
+ال smooth tissues بتكون organ مجموعة ال organs
+
+228
+00:17:32,100 --> 00:17:41,080
+بتعملي ash ال living body زي هاي التفلة طبعا هاي
+
+229
+00:17:41,080 --> 00:17:50,740
+التفلة فيها بتمثل ال body تبعت الإنسان ال
+
+230
+00:17:50,740 --> 00:17:55,820
+body systems هنا باختصارال 11 اللي احنا اتكلمنا
+
+231
+00:17:55,820 --> 00:18:03,480
+عنهم، هنتكلم عنهم شوية زي .. مش عارف من اين ابدأ
+
+232
+00:18:03,480 --> 00:18:09,040
+انانبدأ من الـ Integumentary System اللي هو السطحي
+
+233
+00:18:09,040 --> 00:18:14,800
+الخارجي ال skeletal system ال muscular system ال
+
+234
+00:18:14,800 --> 00:18:19,300
+nervous system ال circulatory system ال endocrine
+
+235
+00:18:19,300 --> 00:18:22,560
+ال lymphatic ال digestive ال respiratory ال
+
+236
+00:18:22,560 --> 00:18:27,160
+urinary ال reproductive system هدولة مجموعة من ال
+
+237
+00:18:27,160 --> 00:18:32,160
+systems اللي بيكونوا ال body و هنتعرف عليهم one by
+
+238
+00:18:32,160 --> 00:18:36,830
+oneنبدأ في الـ Integumentary System احنا بنسميه هو
+
+239
+00:18:36,830 --> 00:18:42,410
+خط الدفاع الأول عن جسم الإنسان أول حاجة احنا
+
+240
+00:18:42,410 --> 00:18:47,190
+بتصيبنا بنقول I من وين أخدنا المستقبلات هذه موجودة
+
+241
+00:18:47,190 --> 00:18:51,590
+في ال skin ابنان الجرح الجرح البسيط قد يؤدي أحيان
+
+242
+00:18:51,590 --> 00:18:56,310
+إلى بطر في أصبع بطر في القدم ليه؟ لأن هو جرح صغير
+
+243
+00:18:56,310 --> 00:19:02,040
+مع ضيابة كفوت معلغس خلينا نقول if circulation في
+
+244
+00:19:02,040 --> 00:19:06,000
+المكان ممكن أو infection أو gangrene أو whatever
+
+245
+00:19:06,000 --> 00:19:12,280
+هذا بس بدأ في ال skinالـ regulatory system هو
+
+246
+00:19:12,280 --> 00:19:16,700
+عبارة عن ال skin ال hairs و ال nails طب ال skin
+
+247
+00:19:16,700 --> 00:19:20,440
+فيه إحساس ال hair مش فيها إحساس ال nails مش فيها
+
+248
+00:19:20,440 --> 00:19:24,680
+إحساس ليش؟ ربنا خلق الأدافير مش فيها إحساس عشان
+
+249
+00:19:24,680 --> 00:19:28,080
+نقدر نقصفها تخيلوا إن لو كلنا بدنا نقصف إجرينا
+
+250
+00:19:28,080 --> 00:19:31,660
+إيدينا أو أدافير إيدينا أو أدافير إجرينا بدنا نصير
+
+251
+00:19:31,660 --> 00:19:35,140
+نصيط أو بدنا نمغنع عن تقصيفة أو كل ما حد مسيكي
+
+252
+00:19:35,140 --> 00:19:38,120
+مقصه عمله في شعر و هك بدنا نصير نصرح معناه الناس
+
+253
+00:19:38,120 --> 00:19:41,800
+بتبقى ماشيةبقى دافير طويلة و أشعار طويلة لكن ال
+
+254
+00:19:41,800 --> 00:19:45,940
+skin هذا هذا المنبه على طول أول ما بينضغط أو
+
+255
+00:19:45,940 --> 00:19:51,160
+بتسيبه لسه قعدت بوس شكة أي إشي فالإنسان بيتنبع
+
+256
+00:19:51,160 --> 00:19:55,700
+فورا external covering كمان بيعطيني صورة جمالية
+
+257
+00:19:55,700 --> 00:20:00,360
+للجسم بيغطي كل أجزاء الجسم ال underlying tissue
+
+258
+00:20:00,360 --> 00:20:06,500
+organs كمان بيعطيني protection بيحفظ
+
+259
+00:20:07,180 --> 00:20:11,680
+تصنيع الفيتامين دي و المهم لو أضائف الجسم و ال
+
+260
+00:20:11,680 --> 00:20:15,620
+sense receptors اللي بتخلينا على طول نحس و بتعطينا
+
+261
+00:20:15,620 --> 00:20:20,340
+ال flash على طول ان انا دعست مثلا على مصمار في هنا
+
+262
+00:20:20,340 --> 00:20:27,060
+سخرة هنا فيه دبوس انا الجزمة ضيقة انجرحت مسكت
+
+263
+00:20:27,060 --> 00:20:31,800
+السكينة و أنا بقطع السلطة و صار في عندي جروح و
+
+264
+00:20:31,800 --> 00:20:37,170
+هكذانروح للـ skeletal system اللي هو الـ bone و ال
+
+265
+00:20:37,170 --> 00:20:41,510
+joints و ال cartilage هي منظومة لحالها بتعطين
+
+266
+00:20:41,510 --> 00:20:46,290
+الشكل الخارجي تبع الجسم بتعطيني support كمان
+
+267
+00:20:46,290 --> 00:20:50,210
+protection تساعد على الحركة أنا بتتحرك عن طريق إيش
+
+268
+00:20:50,210 --> 00:20:53,550
+تحريك الإضام اللي بتتحركها ال musculoskeletal ال
+
+269
+00:20:53,550 --> 00:20:56,890
+muscular system اللي بدنا نتكلم عنه بتعطيني blood
+
+270
+00:20:56,890 --> 00:21:00,810
+vessels كمان بتعمل production لل bloodالـ cells
+
+271
+00:21:00,810 --> 00:21:04,290
+الموجودة عن طريق الـ bone marrow الـ mineral
+
+272
+00:21:04,290 --> 00:21:08,450
+storage بتخزن الـ skeletal system بيخزن كل ال
+
+273
+00:21:08,450 --> 00:21:13,450
+mineral زي الكالسوم و الفوسفات في داخل العثقة أما
+
+274
+00:21:13,450 --> 00:21:16,490
+ال muscular system اللي بيعطي الهيئة كده للجسم
+
+275
+00:21:16,490 --> 00:21:21,250
+تصير الجسم يعني احنا بتطلع على شخص بدين أو شخص
+
+276
+00:21:21,250 --> 00:21:24,830
+ضعيف الشخص الضعيف هو كأنك بتشوفه عدم و متحرك الشخص
+
+277
+00:21:24,830 --> 00:21:28,170
+البدين بتشوفهفي خاصة لو كان رياضي وفي العضلات
+
+278
+00:21:28,170 --> 00:21:32,750
+بتشوف الشكل اللي عام تبعد يعني بيرمز كده للقوة لأن
+
+279
+00:21:32,750 --> 00:21:37,610
+عضلاته قوية شديدة أعطت الشكل تبع الفسم العضلات هي
+
+280
+00:21:37,610 --> 00:21:42,990
+اللي بيسموها اللحمةهي عبارة عن العضلات الاسكليطة
+
+281
+00:21:42,990 --> 00:21:46,490
+المصرية اللي associated connective tissue سيتندن
+
+282
+00:21:46,490 --> 00:21:50,730
+العضلات تطلع البياد اللي موجود هنا هذا البياد كله
+
+283
+00:21:50,730 --> 00:21:54,990
+connective connective tissue على أساس أنها توصل
+
+284
+00:21:54,990 --> 00:22:00,290
+هالمنظومة هذه مع بعضهاالـ functional locomotion،
+
+285
+00:22:00,290 --> 00:22:03,590
+الحركة والانتقال، الـ manipulation of the
+
+286
+00:22:03,590 --> 00:22:06,890
+environment، فيعني أنا لما بدي أجي أزيح الكرسي،
+
+287
+00:22:06,890 --> 00:22:09,710
+بدي عضلات، بدي أزيح المكتب، بدي عضلات، بدي أحرك
+
+288
+00:22:09,710 --> 00:22:14,200
+الماوس، بدي عضلات، بدي أمشي، بدي عضلاتطبعا احنا
+
+289
+00:22:14,200 --> 00:22:16,840
+نطلع ال facial expressions كلها اللي بيعمل العمل
+
+290
+00:22:16,840 --> 00:22:21,660
+ال facial expressions مكشرين مبتسمين كل ال facial
+
+291
+00:22:21,660 --> 00:22:26,760
+expressions هذه بتقديها العضلات طبعا بتحافظ على ال
+
+292
+00:22:26,760 --> 00:22:29,620
+position احنا نشوف ناس كتير محطبين في ناس بتلاقي
+
+293
+00:22:29,620 --> 00:22:33,520
+مستهجش position في ناس لأ مهضين والله هم رتبين
+
+294
+00:22:33,520 --> 00:22:38,480
+وكمان الحركة عن طريقالعضلات بتعطيني heat
+
+295
+00:22:38,480 --> 00:22:41,920
+production، عشان heat production بتدفّي، يعني احنا
+
+296
+00:22:41,920 --> 00:22:45,000
+بنلاحظ احنا اول ما بنبرد بنبدأ نفرّك في اديانا،
+
+297
+00:22:45,000 --> 00:22:48,560
+بنبدأ نمط، بنبدأ نعمل رياضة عشان إيه؟ عشان نحرك
+
+298
+00:22:48,560 --> 00:22:53,480
+هالطاقة الكامية اللي موجودة و بالعربي ندفّيهو ال
+
+299
+00:22:53,480 --> 00:22:57,200
+circulatory system فهو ال cardiovascular system و
+
+300
+00:22:57,200 --> 00:22:59,980
+ال lymphatic system ايش وظيفتهم ال transportation
+
+301
+00:22:59,980 --> 00:23:03,760
+يعني وسيلة المواصلات للدم هي بتكون عبارة عن
+
+302
+00:23:03,760 --> 00:23:09,660
+القنوات اللي هي الموجودة في ال vascular system و
+
+303
+00:23:09,660 --> 00:23:12,340
+ال lymphatic systemfor the photomatransportation
+
+304
+00:23:12,340 --> 00:23:15,580
+of minerals within the body بتوزع المواد الغذائية
+
+305
+00:23:15,580 --> 00:23:20,620
+هذه على ال body وكمان to and from internal and
+
+306
+00:23:20,620 --> 00:23:23,980
+external environment طيب احنا في عندنا ال internal
+
+307
+00:23:23,980 --> 00:23:28,260
+environment وفي عندنا ال external environment عن
+
+308
+00:23:28,260 --> 00:23:34,620
+طريقها احنا ممكن ننظم الجسم الانسان ال
+
+309
+00:23:34,620 --> 00:23:42,540
+cardiovascular system زي ال heartوالـ blood
+
+310
+00:23:42,540 --> 00:23:48,060
+vessels function transportation of the blood البلد
+
+311
+00:23:48,060 --> 00:23:52,460
+عادة بيكون فيه بيحمل أكسوجين و ثاني أكسيد الكربون
+
+312
+00:23:54,420 --> 00:23:58,100
+احنا بناخد مفس و بناخد أكسجين و بنطلع و بنطلع ثاني
+
+313
+00:23:58,100 --> 00:24:02,000
+أكسيد الكربون كيف بتصير هذه العملية هنشرحها في
+
+314
+00:24:02,000 --> 00:24:06,560
+وقتها ال nutrients أو المواد الغذائية ال waste
+
+315
+00:24:06,560 --> 00:24:09,820
+product كيف بتطلع كلها عن طريق ال cardiovascular
+
+316
+00:24:09,820 --> 00:24:16,650
+system ال blood is composed of plasma and cellsالـ
+
+317
+00:24:16,650 --> 00:24:19,470
+lymphatic طبعاً الـ lymphatic organs زي الـ spleen
+
+318
+00:24:19,470 --> 00:24:23,330
+و الـ lymph nodes و الـ thymus، lymphatic vessels
+
+319
+00:24:23,330 --> 00:24:27,950
+كلها برفتها transportation of the lymph، lymph is
+
+320
+00:24:27,950 --> 00:24:34,570
+divided، derived، بيجي من ال tissue، ال fluid و ال
+
+321
+00:24:34,570 --> 00:24:39,730
+white، موجود في ال white blood cells عشان تعزز
+
+322
+00:24:39,730 --> 00:24:43,590
+جهاز المناعة اللي احنا بنتكلم عنه اللي هو ال
+
+323
+00:24:43,590 --> 00:24:48,640
+immune systemالـ component of immune system الـ
+
+324
+00:24:48,640 --> 00:24:52,140
+immune organ الـ bone marrow و الـ thymus ال white
+
+325
+00:24:52,140 --> 00:24:55,400
+blood cells ال lymphocytes بنسميها و ال macro
+
+326
+00:24:55,400 --> 00:25:01,140
+phages اللي هي الخلايا الأكلة هذه اللي بتساعد على
+
+327
+00:25:01,140 --> 00:25:08,140
+ال phagocytosis ال function defense دفاع بس الدفاع
+
+328
+00:25:08,140 --> 00:25:11,960
+و احنا خط دفاع الأول قلنا ال skin لكن ال immune
+
+329
+00:25:11,960 --> 00:25:17,660
+system هو اللي بدي هاجم أيبكتيريا، أي فيروس، أي
+
+330
+00:25:17,660 --> 00:25:23,040
+إشي خارجي نظام المنظومة اللي هو الطبيعي أو ال
+
+331
+00:25:23,040 --> 00:25:26,780
+normal اللي موجود في الجسم على طول بيعمل دفعات
+
+332
+00:25:27,960 --> 00:25:31,920
+بتبدأ الغدّة اللي هي thymus، gland تشغل على أساس
+
+333
+00:25:31,920 --> 00:25:39,460
+أنها تحفز المناعة و تهاجم كل الخلايا هذه اللي هجمت
+
+334
+00:25:39,460 --> 00:25:42,780
+الجسم و تقضي عليها و لو صار خلل في جهاز المناعة
+
+335
+00:25:42,780 --> 00:25:47,600
+ممكن يصير يأكل بعضه يعني يأكل المنيح والسيئ من
+
+336
+00:25:47,600 --> 00:25:51,720
+الخلايا وهذا بيبقى إشي مرضي أما ال nervous system
+
+337
+00:25:51,720 --> 00:25:57,170
+وظيفته ال control في عندنا اتنينأساسيا من مكونات
+
+338
+00:25:57,170 --> 00:25:59,790
+ال nervous system عنا ال central nervous system و
+
+339
+00:25:59,790 --> 00:26:03,850
+ال peripheral ال central عبارة عن ال spinal cord و
+
+340
+00:26:03,850 --> 00:26:07,730
+ال brain و ال peripheral عبارة عن ال nerve و ال
+
+341
+00:26:07,730 --> 00:26:14,010
+receptors اللي موجودة في الجسم وضيفته control fast
+
+342
+00:26:14,010 --> 00:26:21,370
+hard wiredأول حاجة أنا بتعرضلها إجا حد بده يوقعني
+
+343
+00:26:21,370 --> 00:26:24,830
+على طول أنا بنتبه، بمسك إيده أو برفع إيدي بهذا
+
+344
+00:26:24,830 --> 00:26:28,610
+الشكل، حطيت إيدي وحملت .. مسكت ال microwave مثلا
+
+345
+00:26:28,610 --> 00:26:33,480
+طلعت كباية أو صحمة سخن برميهدعست على مصمار برفع
+
+346
+00:26:33,480 --> 00:26:38,280
+رجلي، اتعرضت لخطر معين بخاف أو بشد على جسمي و هكذا
+
+347
+00:26:38,280 --> 00:26:42,980
+Respond to external and internal environments طبعا
+
+348
+00:26:42,980 --> 00:26:46,040
+بيجيه الإحساس في ال external environment طب كيف بي
+
+349
+00:26:46,040 --> 00:26:48,380
+respond to the external environment؟ بيجيه الإحساس
+
+350
+00:26:48,380 --> 00:26:51,340
+أنا لقيتها قاعدة في التكييف حاسة الجو بارد، طلعت
+
+351
+00:26:51,340 --> 00:26:56,030
+برا بحسه حامل، والله الجو بارد كتير، تلجبحس هذا
+
+352
+00:26:56,030 --> 00:26:58,990
+اجتني من احمل امسكت اشي سخن هذا external
+
+353
+00:26:58,990 --> 00:27:03,310
+environment بتيجي انا لجسمي اما ال endocrine
+
+354
+00:27:03,310 --> 00:27:08,830
+systemطبعا المسئول عن ال control السريع اللي هو ال
+
+355
+00:27:08,830 --> 00:27:11,650
+nervous system على ال control البطيء اللي هو ال
+
+356
+00:27:11,650 --> 00:27:14,550
+endocrine system اللي هو عبارة عن ال gland to
+
+357
+00:27:14,550 --> 00:27:18,990
+secret that secretes hormones ال hormones هذه هي
+
+358
+00:27:18,990 --> 00:27:23,070
+اللي بتنظم الجسم تسيسي الغدد المختلفة ال pituitary
+
+359
+00:27:23,070 --> 00:27:27,550
+ال pancreas الthyroid اللي بيسموه الغدد القدرية و
+
+360
+00:27:27,550 --> 00:27:31,750
+القدرية و ال pancreas اللي بيفرزلي هرمون الانسولين
+
+361
+00:27:31,750 --> 00:27:36,020
+و هكذاأما الـ Function هي الـ Slow Chemicals اللي
+
+362
+00:27:36,020 --> 00:27:39,160
+هي ترددت الفعل السريع يحنا بناخدهم ال nervous
+
+363
+00:27:39,160 --> 00:27:42,620
+system أما الرددت الفعل البطيقة اللي هي بتعمل
+
+364
+00:27:42,620 --> 00:27:47,640
+تنظيم لبيئة الجسم أو بتحافظ على ال homogenous أو
+
+365
+00:27:47,640 --> 00:27:53,060
+ال homostasis و ال homostasis هو عبارة عن ال
+
+366
+00:27:53,060 --> 00:27:56,960
+endocrine system regulates ال process such as a
+
+367
+00:27:56,960 --> 00:28:00,920
+growth reproductive and nutrient uses
+
+368
+00:28:02,740 --> 00:28:05,420
+Respiratory System هو عبارة عن الـ Lung و كل الـ
+
+369
+00:28:05,420 --> 00:28:08,760
+Tube زي التراكيا و الـ Pancreas و غيره و الـLarynx
+
+370
+00:28:08,760 --> 00:28:12,080
+اللي هي ال vocal cord اللي هي عبارة عن الحنجرة
+
+371
+00:28:12,080 --> 00:28:16,500
+اللي موجودة فيها الـ Voice Box اللي بيخلنا نقدر
+
+372
+00:28:16,500 --> 00:28:21,710
+نصدر هذه الأصواتطبعا إيش؟ وظيفة ال lungs اللي هي
+
+373
+00:28:21,710 --> 00:28:25,190
+exchange of respiratory gases الأكسجين، يعني احنا
+
+374
+00:28:25,190 --> 00:28:30,350
+بناخد نفس بناخد الأكسجين و بناخد منه ثاني أكسيد
+
+375
+00:28:30,350 --> 00:28:33,930
+الدم بيمر، بياخد الأكسجين من ال alveoli و بيعطيها
+
+376
+00:28:33,930 --> 00:28:38,300
+ثاني أكسيد الكربونهذه عملية الشغيق أما الـ Zephyr
+
+377
+00:28:38,300 --> 00:28:41,680
+فإحنا بناخد ثاني أكسيد الـ Carbon الـ Voice
+
+378
+00:28:41,680 --> 00:28:44,400
+Production إحنا لما بنتكلم لازم يكون فيه يعني
+
+379
+00:28:44,400 --> 00:28:47,740
+نلاحظ أن الناس بتبقى عاملة تركز ثم هنا في الفتحة
+
+380
+00:28:47,740 --> 00:28:51,580
+في القصة اللوائية ما بيطلع صوتها لأن الهواء
+
+381
+00:28:51,580 --> 00:28:58,090
+وترددات الهواء ماوصلت للأحبال الصوتيةال digestive
+
+382
+00:28:58,090 --> 00:29:01,870
+system هو الجهاز الهضمي فيه ال alimentary canal زي
+
+383
+00:29:01,870 --> 00:29:05,010
+ال mouth، ال pharynx، ال oesophagus، في عندنا قناة
+
+384
+00:29:05,010 --> 00:29:09,110
+بنسميها القناة الهضمية وفي عندنا اللي هي ملحقات
+
+385
+00:29:09,110 --> 00:29:13,030
+الجهاز الهضمي زي الكبد، ال liver، saliva gland، ال
+
+386
+00:29:13,030 --> 00:29:16,450
+pancreas، هذه بنسميها ال spleen، كلها ملحقات
+
+387
+00:29:16,450 --> 00:29:20,270
+الجهاز الهضمي و the feta break down the food into
+
+388
+00:29:20,270 --> 00:29:25,230
+smallerobject عشان نقدر احنا نعمله absorption و
+
+389
+00:29:25,230 --> 00:29:30,910
+نستفيد من المواد الغذائية اللي احنا بناخدها اثناء
+
+390
+00:29:30,910 --> 00:29:34,610
+من الطعام اللي احنا بناخده الشراب ال absorption
+
+391
+00:29:34,610 --> 00:29:38,430
+عشان تروح لل blood و تروح على أجهزة في الجسم
+
+392
+00:29:38,430 --> 00:29:43,770
+المختلفة و كمان حتى نتخلص من ال waste productيعني
+
+393
+00:29:43,770 --> 00:29:47,330
+متخيلين انه احنا لو جسمنا بس بيدخله السموم هذه
+
+394
+00:29:47,330 --> 00:29:50,390
+بتبقى لها في جسمنا كيف بيكون وضعنا لو صار فيه
+
+395
+00:29:50,390 --> 00:29:53,630
+مشكلة، لو على الأقل يعني .. يعني upset بقاش ال
+
+396
+00:29:53,630 --> 00:29:58,150
+constipation، بتحجر ال stool، روات، ال intestine،
+
+397
+00:29:58,150 --> 00:30:03,000
+وما بيقدر الإنسان يخرجه؟نجلال الورينري سيستم اللي
+
+398
+00:30:03,000 --> 00:30:07,620
+هو بتكون من الكدني و الوريتارز و الورينري بلدر و
+
+399
+00:30:07,620 --> 00:30:11,580
+الوريثرا هدولة مكونات الورينري ترات اللي بيساعدنا
+
+400
+00:30:11,580 --> 00:30:16,620
+على التخلص من السموم عن طريق تنقيتها بواسطة
+
+401
+00:30:16,620 --> 00:30:20,920
+الكليتين eliminate was زي ال nitrogen from the
+
+402
+00:30:20,920 --> 00:30:24,880
+blood between blood and external environment
+
+403
+00:30:26,940 --> 00:30:33,560
+regulate water electrolyte acid base balance بينظم
+
+404
+00:30:33,560 --> 00:30:42,400
+كل مكونات الدم عن طريق ال urinary system ال
+
+405
+00:30:42,400 --> 00:30:47,720
+reproductive هو عبارة عن إيش؟ هو عبارة عن المحافظة
+
+406
+00:30:47,720 --> 00:30:52,680
+على الحياة و عن استمرارية الحياة التكاثر خلينا
+
+407
+00:30:52,680 --> 00:30:56,610
+نقول فيه أنالـ Male Reproductive System والـ
+
+408
+00:30:56,610 --> 00:31:00,990
+Female Reproductive System وظيفتهم بـ Reproduction
+
+409
+00:31:00,990 --> 00:31:06,670
+of the Species المحافظة ده خلينا نقول على الكون،
+
+410
+00:31:06,670 --> 00:31:12,690
+الإنتاج الهرمون Influence Structure and Function
+
+411
+00:31:12,690 --> 00:31:18,370
+طبعاً فيه إنه هرمونات خاصة بجهاز التناثل الأمطوي
+
+412
+00:31:18,370 --> 00:31:22,670
+والذكري Sexual Demo
+
+413
+00:31:23,520 --> 00:31:29,460
+morphic spaces بيساعد في عملية ال sexual،
+
+414
+00:31:29,460 --> 00:31:33,860
+العلاقات، خليني أقول الجنسية اللي بينتج عنها ال
+
+415
+00:31:33,860 --> 00:31:37,700
+reproduction أو إنتاج الإنسان أو التكاثر، خليني
+
+416
+00:31:37,700 --> 00:31:42,790
+أسميه بـبهنا بنقدر احنا نوقف محاضرتنا لليوم لإن ما
+
+417
+00:31:42,790 --> 00:31:47,610
+في عندنا هنتقل لموضوع جديد هو ال anatomical
+
+418
+00:31:47,610 --> 00:31:53,050
+terminologies الخاصة بال Anatomy اللي كل شخص من ..
+
+419
+00:31:53,050 --> 00:31:59,490
+كل خريج من العلوم الصحية يجب أن يتعلمها أو يعلمها
+
+420
+00:31:59,490 --> 00:32:03,030
+أو يحفظها غيبا لإن هذه هتستمر معاه على السنوات
+
+421
+00:32:03,030 --> 00:32:06,250
+اللي أنا بتسهل عنينا عملية الحفظ و المتابعة
+
+422
+00:32:06,550 --> 00:32:10,530
+والدراسة ما بعد هيك، يعطيكم العافية والسلام عليكم
+
+423
+00:32:10,530 --> 00:32:11,190
+ورحمة الله
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..14efdc7858ce60b968ba2f2aa68d11c66a5ed8de
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU_raw.json
@@ -0,0 +1 @@
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0.94287109375}, {"start": 1900.49, "end": 1900.71, "word": " احنا", "probability": 0.8660481770833334}, {"start": 1900.71, "end": 1901.01, "word": " نوقف", "probability": 0.9532877604166666}, {"start": 1901.01, "end": 1901.63, "word": " محاضرتنا", "probability": 0.9412109375}, {"start": 1901.63, "end": 1902.13, "word": " لليوم", "probability": 0.8785807291666666}, {"start": 1902.13, "end": 1902.73, "word": " لإن", "probability": 0.8655598958333334}, {"start": 1902.73, "end": 1902.79, "word": " ما", "probability": 0.638671875}, {"start": 1902.79, "end": 1902.99, "word": " في", "probability": 0.8623046875}, {"start": 1902.99, "end": 1904.15, "word": " عندنا", "probability": 0.6614990234375}, {"start": 1904.15, "end": 1905.55, "word": " هنتقل", "probability": 0.84527587890625}, {"start": 1905.55, "end": 1905.97, "word": " لموضوع", "probability": 0.9747314453125}, {"start": 1905.97, "end": 1906.41, "word": " جديد", "probability": 0.9930013020833334}, {"start": 1906.41, "end": 1906.71, "word": " هو", "probability": 0.91259765625}, {"start": 1906.71, "end": 1906.89, "word": " ال", "probability": 0.9541015625}, {"start": 1906.89, "end": 1907.61, "word": " anatomical", "probability": 0.7999674479166666}, {"start": 1907.61, "end": 1908.73, "word": " terminologies", "probability": 0.810302734375}, {"start": 1908.73, "end": 1909.75, "word": " الخاصة", "probability": 0.9537760416666666}, {"start": 1909.75, "end": 1909.97, "word": " بال", "probability": 0.98876953125}, {"start": 1909.97, "end": 1910.57, "word": " Anatomy", "probability": 0.62890625}, {"start": 1910.57, "end": 1910.85, "word": " اللي", "probability": 0.75732421875}, {"start": 1910.85, "end": 1911.27, "word": " كل", "probability": 0.97802734375}, {"start": 1911.27, "end": 1912.29, "word": " شخص", "probability": 0.9969075520833334}, {"start": 1912.29, "end": 1912.67, "word": " من", "probability": 0.953125}, {"start": 1912.67, "end": 1913.05, "word": " ..", "probability": 0.51171875}, {"start": 1913.05, "end": 1913.49, "word": " كل", "probability": 0.9375}, {"start": 1913.49, "end": 1914.77, "word": " خريج", "probability": 0.82666015625}, {"start": 1914.77, "end": 1915.07, "word": " من", "probability": 0.9912109375}, {"start": 1915.07, "end": 1915.55, "word": " العلوم", "probability": 0.94677734375}, {"start": 1915.55, "end": 1916.25, "word": " الصحية", "probability": 0.9890950520833334}, {"start": 1916.25, "end": 1917.07, "word": " يجب", "probability": 0.9895833333333334}, {"start": 1917.07, "end": 1917.43, "word": " أن", "probability": 0.54052734375}, {"start": 1917.43, "end": 1918.45, "word": " يتعلمها", "probability": 0.99306640625}, {"start": 1918.45, "end": 1918.81, "word": " أو", "probability": 0.74755859375}, {"start": 1918.81, "end": 1919.49, "word": " يعلمها", "probability": 0.8981119791666666}, {"start": 1919.49, "end": 1919.75, "word": " أو", "probability": 0.82763671875}, {"start": 1919.75, "end": 1920.21, "word": " يحفظها", "probability": 0.97802734375}, {"start": 1920.21, "end": 1920.65, "word": " غيبا", "probability": 0.945068359375}, {"start": 1920.65, "end": 1920.93, "word": " لإن", "probability": 0.9195963541666666}, {"start": 1920.93, "end": 1921.19, "word": " هذه", "probability": 0.379638671875}, {"start": 1921.19, "end": 1921.77, "word": " هتستمر", "probability": 0.9293212890625}, {"start": 1921.77, "end": 1922.17, "word": " معاه", "probability": 0.97900390625}, {"start": 1922.17, "end": 1922.63, "word": " على", "probability": 0.91162109375}, {"start": 1922.63, "end": 1923.03, "word": " السنوات", "probability": 0.8731689453125}, {"start": 1923.03, "end": 1923.13, "word": " اللي", "probability": 0.952880859375}, {"start": 1923.13, "end": 1923.23, "word": " أنا", "probability": 0.68798828125}, {"start": 1923.23, "end": 1923.65, "word": " بتسهل", "probability": 0.92431640625}, {"start": 1923.65, "end": 1924.03, "word": " عنينا", "probability": 0.6931966145833334}, {"start": 1924.03, "end": 1924.45, "word": " عملية", "probability": 0.9873046875}, {"start": 1924.45, "end": 1925.07, "word": " الحفظ", "probability": 0.9563802083333334}, {"start": 1925.07, "end": 1925.49, "word": " و", "probability": 0.6416015625}, {"start": 1925.49, "end": 1926.25, "word": " المتابعة", "probability": 0.9677734375}], "temperature": 1.0}, {"id": 88, "seek": 193119, "start": 1926.55, "end": 1931.19, "text": "والدراسة ما بعد هيك، يعطيكم العافية والسلام عليكم ورحمة الله", "tokens": [2407, 6027, 3215, 23557, 3794, 3660, 19446, 39182, 39896, 4117, 12399, 37495, 9566, 1829, 24793, 18863, 31845, 10632, 16070, 3794, 37440, 25894, 24793, 4032, 2288, 35571, 3660, 21984], "avg_logprob": -0.1857489224137931, "compression_ratio": 1.2906976744186047, "no_speech_prob": 0.0, "words": [{"start": 1926.55, "end": 1927.49, "word": "والدراسة", "probability": 0.8961588541666666}, {"start": 1927.49, "end": 1927.75, "word": " ما", "probability": 0.6171875}, {"start": 1927.75, "end": 1928.39, "word": " بعد", "probability": 0.986328125}, {"start": 1928.39, "end": 1928.81, "word": " هيك،", "probability": 0.701171875}, {"start": 1928.81, "end": 1929.19, "word": " يعطيكم", "probability": 0.75482177734375}, {"start": 1929.19, "end": 1929.73, "word": " العافية", "probability": 0.9562174479166666}, {"start": 1929.73, "end": 1930.07, "word": " والسلام", "probability": 0.74755859375}, {"start": 1930.07, "end": 1930.53, "word": " عليكم", "probability": 0.961181640625}, {"start": 1930.53, "end": 1931.03, "word": " ورحمة", "probability": 0.97119140625}, {"start": 1931.03, "end": 1931.19, "word": " الله", "probability": 0.97021484375}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1932.0395625, "duration_after_vad": 1900.2593749999983}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..e20b905b2cba457a323e21460dfe1e2c37d6fc55
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/DOB4Itl4gDU_raw.srt
@@ -0,0 +1,1692 @@
+1
+00:00:05,870 --> 00:00:09,630
+بسم الله الرحمن الرحيم الصلاة والسلام علي سيدنا
+
+2
+00:00:09,630 --> 00:00:13,730
+محمد سيد المرسلين محاضرتنا الأولى في مساق ال
+
+3
+00:00:13,730 --> 00:00:18,110
+anatomy للفصل الصيفي ان شاء الله بنكون معاكوا أنا
+
+4
+00:00:18,110 --> 00:00:21,890
+دكتورة علي القشاوي قصية علاج طبيعي و تأهيل مدير
+
+5
+00:00:21,890 --> 00:00:25,010
+دائرة التأهيل والعلاج الطبيعي في وزارة الصحة
+
+6
+00:00:25,010 --> 00:00:30,550
+محاضرة بالجامعة الإسلامية بقسم العلاج الطبيعي
+
+7
+00:00:30,550 --> 00:00:37,160
+لكلية العلوم الصحيةانشاء الله طبعا يكون محادرتنا
+
+8
+00:00:37,160 --> 00:00:41,120
+لليوم و المحادرات اللي جاية من المحادرات اللي نكون
+
+9
+00:00:41,120 --> 00:00:46,360
+قيمة لإنها مساقة تشريح من المساقات الأساسية في ..
+
+10
+00:00:46,360 --> 00:00:51,360
+لأي متخصص في مجال العلوم الصحية، لازم نبقى نعرف
+
+11
+00:00:51,360 --> 00:00:55,180
+على الأقل تركيبة الجسم هذا اللي احنا بنتعامل معاه
+
+12
+00:00:55,260 --> 00:00:59,540
+أنتوا متخصصين في مجال العلوم الصحية و طبعا أنا
+
+13
+00:00:59,540 --> 00:01:02,680
+بتمنى لكم التوفيه لإن أنا بعرف أنه أكيد هيكون معمط
+
+14
+00:01:02,680 --> 00:01:07,580
+الله بطالبات من كلية الطب و العلوم الصحية و هدولة
+
+15
+00:01:07,580 --> 00:01:11,640
+أكيد يعني هيكونوا في يوم الأيام خرجين بيرفعوا
+
+16
+00:01:11,640 --> 00:01:15,840
+الراس أكيد هيتعاملوا مع هذا الإنسان و هيكونوا
+
+17
+00:01:15,840 --> 00:01:21,900
+مثابت يعني مقدمين خدمة صحية لهذا الشخص و .. و أكيد
+
+18
+00:01:21,900 --> 00:01:28,000
+منهم هيكونواناس قادرين على تحسين جودة حياة الإنسان
+
+19
+00:01:28,000 --> 00:01:31,660
+و كذلك على نسميه ال life saving لكي يحافظوا على
+
+20
+00:01:31,660 --> 00:01:39,140
+حياة هذا الإنسان و منع الإعاقة و خليني أقول على
+
+21
+00:01:40,290 --> 00:01:44,270
+قدراته لنحافظ على قدراته الصحية حتى يكون إنسان
+
+22
+00:01:44,270 --> 00:01:47,530
+مستقل عشان هيك لازم يكون فيه علنا معرفة بعرف انكم
+
+23
+00:01:47,530 --> 00:01:50,070
+انتوا من تخصيصات مختلفة منها الطب منها العلاج
+
+24
+00:01:50,070 --> 00:01:55,210
+الطبيعي منها البصريات منها التحاليل الطبية طبعا
+
+25
+00:01:55,210 --> 00:02:00,680
+نحاول أن نكون يعني مش هنخل في قمطالتشريح لأن أكيد
+
+26
+00:02:00,680 --> 00:02:04,580
+انتوا هذا المصاد سيعاد انكوا كل واحد حسب التخصص
+
+27
+00:02:04,580 --> 00:02:09,840
+اللي هو بده يروح عليه خلنا نتعرف في البداية على
+
+28
+00:02:09,840 --> 00:02:16,360
+التعريف ال anatomy ال anatomy هو علم التشريح طيب
+
+29
+00:02:16,360 --> 00:02:20,860
+هذه الكلمة من وين إجت؟ إجت هي كلمة إغريقية أو
+
+30
+00:02:20,860 --> 00:02:28,600
+Greek بقنها to cut up انها نقطع او ن dissectthe
+
+31
+00:02:28,600 --> 00:02:31,560
+science that deal with the structure of the body
+
+32
+00:02:31,560 --> 00:02:34,840
+طول عمرنا بنسمع عن حاجة اسمها anatomy و حاجة اسمها
+
+33
+00:02:34,840 --> 00:02:38,400
+physiology ممكن أنا شخصيا لما درست درستهم اتنين مع
+
+34
+00:02:38,400 --> 00:02:42,640
+بعض في كتاب اسمه anatomy and physiology كان سؤال
+
+35
+00:02:42,640 --> 00:02:45,600
+بت الفصل بين ال anatomy و ال physiology لأن انت ال
+
+36
+00:02:45,600 --> 00:02:48,980
+anatomy بيعتني بال structure تبع الأشياء أما ال
+
+37
+00:02:48,980 --> 00:02:52,060
+physiology بيعتني بالوظيفة يعني عشان لازم تعرف
+
+38
+00:02:52,060 --> 00:02:57,410
+الوظيفة لازم تعرف ال structureمافيش إمكانية صعوبة
+
+39
+00:02:57,410 --> 00:03:01,230
+الفصل ما بين هدول إلا إنه في بعض المثاقات بتفصل ما
+
+40
+00:03:01,230 --> 00:03:04,690
+بينهم زي المثاق اللي احنا هتكلم بس عن ال structure
+
+41
+00:03:04,690 --> 00:03:09,150
+تبع ال body و أجزاء ال body المختلفة طب ماهيش
+
+42
+00:03:09,150 --> 00:03:12,710
+أنواع ال anatomy؟ في عندنا ال gross anatomy اللي
+
+43
+00:03:12,710 --> 00:03:16,650
+هو بيعتني بالمظهرالخارجى او اللى ما يرعى بالعين
+
+44
+00:03:16,650 --> 00:03:20,750
+المجردة فيه ال microscopic anatomy اللى ما بنقدرش
+
+45
+00:03:20,750 --> 00:03:24,810
+نشوفه بالعين المجردة بنشوفه تحت ال maestroscope ال
+
+46
+00:03:24,810 --> 00:03:29,170
+developmental بنشوف التطور علم التطور الأشخاص أو
+
+47
+00:03:29,170 --> 00:03:33,330
+الأفراد من ال embryology لحد ما يصير الشخص كبير
+
+48
+00:03:33,330 --> 00:03:36,990
+بالسن وفيه ال comparative anatomy اللى بيقارن
+
+49
+00:03:36,990 --> 00:03:41,490
+الكائنات مع بعضها او الفقريات مع بعضها لو تكلمنا
+
+50
+00:03:41,490 --> 00:03:46,620
+عن ال human beingsطب إيش هو ال gross anatomy؟ ال
+
+51
+00:03:46,620 --> 00:03:51,240
+gross anatomy هو العلم اللي بيعتني بال structure
+
+52
+00:03:51,240 --> 00:03:55,060
+with naked eyes، يعني أنا بعيني بقدر أشوف الشخص
+
+53
+00:03:55,060 --> 00:04:00,050
+هذا، بقدر أقول الشخص قداني، هذا فيه headفي
+
+54
+00:04:00,050 --> 00:04:02,910
+shoulders، في upper limbs، في lower limbs، في
+
+55
+00:04:02,910 --> 00:04:09,770
+trunk، في abdomen، هذا كله بشوفه طيب لو فتحت أنا
+
+56
+00:04:09,770 --> 00:04:14,910
+ومسكت مشرط و جيت على جثة أو ومسكت skeleton بقدر
+
+57
+00:04:14,910 --> 00:04:21,330
+أقول والله هذه العدمة هي ال femur، هذه ال scapula،
+
+58
+00:04:21,330 --> 00:04:25,930
+بشوفها بعيني، مامحتاج انا أحطها under microscopeكل
+
+59
+00:04:25,930 --> 00:04:30,630
+هذه الأشياء هنتعرف عليها لما نجي نستخدم أو نتعرف
+
+60
+00:04:30,630 --> 00:04:35,910
+على ال region by region فبنتكلم عنه أنواعه طيب ال
+
+61
+00:04:35,910 --> 00:04:38,870
+gross anatomy مش بتتكلم regionally يعني بيستخدم ال
+
+62
+00:04:38,870 --> 00:04:40,890
+upper part of the body lower part of the
+
+63
+00:04:40,890 --> 00:04:43,610
+extremities ال appendicular system اللي هو ال
+
+64
+00:04:43,610 --> 00:04:49,170
+trunk و ال head ال axial .. sorry ال axial اللي هو
+
+65
+00:04:49,170 --> 00:04:52,510
+ال head و ال trunk ال appendicular هيالاطراف ال
+
+66
+00:04:52,510 --> 00:04:55,770
+regional لكن ال system يستخدم يتكلم عن ال
+
+67
+00:04:55,770 --> 00:04:59,150
+respiratory system ال cardiovascular system عن ال
+
+68
+00:04:59,150 --> 00:05:02,430
+endocrine
+
+69
+00:05:02,430 --> 00:05:06,210
+system ال integumentary system كل ال system في 11
+
+70
+00:05:06,210 --> 00:05:12,050
+system of the body ممكن يتدرسوا one by oneالـ
+
+71
+00:05:12,050 --> 00:05:15,810
+Gastrointestinal وغيره هنشوفهم كما نشوف أما ال
+
+72
+00:05:15,810 --> 00:05:19,610
+microscopic فهو وين؟ هذا بيعتمد بالأشياء اللي احنا
+
+73
+00:05:19,610 --> 00:05:22,930
+مابنقدر نشوفها بالعين المجردة نشوفها under
+
+74
+00:05:22,930 --> 00:05:28,250
+microscope ال cytology و ال histology و ال
+
+75
+00:05:28,250 --> 00:05:33,470
+organologyالـ cytology بيشوف الخلية و بيحاول يدرس
+
+76
+00:05:33,470 --> 00:05:37,490
+هذه الخلية إيش خصائص الخلية هذه، فيها nucleus، مش
+
+77
+00:05:37,490 --> 00:05:40,270
+فيها nucleus، فيها cytoplasm، فيها .. و كل هذه
+
+78
+00:05:40,270 --> 00:05:43,610
+الأشياء مين اللي بيشوفها علم الـ cytology under
+
+79
+00:05:43,610 --> 00:05:47,330
+microscopistsالتيلوجي بتتكلم عن ال tissue نفسها،
+
+80
+00:05:47,330 --> 00:05:51,390
+هنقول إيه؟ إن السل مكون أساسي مثلا لل organ،
+
+81
+00:05:51,390 --> 00:05:54,970
+مجموعة من السل بتتحد، بتكون إلها خواص معينة بتعمل
+
+82
+00:05:54,970 --> 00:05:58,530
+tissue، خواص ال tissue هذه اللي هي لما بتتركب مع
+
+83
+00:05:58,530 --> 00:06:01,990
+بعضها أو بتتحد مع بعضها، بتتكون لي حاجة اسمها
+
+84
+00:06:01,990 --> 00:06:08,270
+organ، فهن كل واحد من هذه المكونات ممكن تندرس
+
+85
+00:06:08,270 --> 00:06:13,810
+under microscopeأما الـ Developmental فهو بيقتنع
+
+86
+00:06:13,810 --> 00:06:18,490
+بالـ anatomical changes during ال life cycle طب ال
+
+87
+00:06:18,490 --> 00:06:22,410
+life cycle هذه بتبدأ من ال emperiology وبعدين
+
+88
+00:06:22,410 --> 00:06:28,290
+بتبدأ التطور التطور الجنين من اتحاد ال spare مع ال
+
+89
+00:06:28,290 --> 00:06:34,050
+organ لحد ما يتكون الجنين في يوم ما يصير فيه قيلو
+
+90
+00:06:34,050 --> 00:06:37,230
+ولادة فهذا بيسموه emperiology أما ال postnatal
+
+91
+00:06:37,230 --> 00:06:43,670
+developmentاللي يبدأ من عمر واحد لنهاية العمر سواء
+
+92
+00:06:43,670 --> 00:06:48,850
+إما تبدأ العمر لأيام، لشهور، لسنوات أو سنوات عديدة
+
+93
+00:06:48,850 --> 00:06:54,530
+و لو الإنسان وصل فيه لعمر متقدم بالسن فهذا بيسمى
+
+94
+00:06:54,530 --> 00:06:58,470
+anatomical difference طبعا في فرق بين عدمة ال baby
+
+95
+00:06:58,470 --> 00:07:01,790
+اللي هي معظمها cartilage مع عدمة ال adolescence
+
+96
+00:07:01,790 --> 00:07:06,790
+اللي هي مبنية هنا في سئلها ossificationمعظمة الـ
+
+97
+00:07:06,790 --> 00:07:12,710
+Old Ages اللي هي osteoporotic فهنا هذا الدراسة
+
+98
+00:07:12,710 --> 00:07:19,380
+بتصير معمقة على جميع الخلاياأما ال comparative
+
+99
+00:07:19,380 --> 00:07:22,420
+anatomy اللي هو بيقارن الفقريات بعضها ال
+
+100
+00:07:22,420 --> 00:07:25,400
+comparison of the structure between organisms يعني
+
+101
+00:07:25,400 --> 00:07:31,280
+إحنا شايفين hand ل human و ل dog و ل bird كل واحدة
+
+102
+00:07:31,280 --> 00:07:35,940
+هادي إيد و هادي إيد و هادي إيد كل واحدة إلها وظيفة
+
+103
+00:07:36,600 --> 00:07:42,120
+هي إيد حقيقي لكن هي الوظيفة اللي بتقدرها حسب الشخص
+
+104
+00:07:42,120 --> 00:07:48,140
+أو الحائق الكائن اللي هو بتتبعله و بنشوف فيه تشابه
+
+105
+00:07:48,140 --> 00:07:53,040
+أحيانا بيكون أن معظمها فيها عضمة الهيوميراس وبعدين
+
+106
+00:07:53,040 --> 00:07:59,820
+عضمتين تحت وهكذا يبقى هي ال comparison between
+
+107
+00:07:59,820 --> 00:08:04,760
+destruction among vertebrae classes أو الفقرية
+
+108
+00:08:04,760 --> 00:08:13,420
+تمام؟هو العلم الخاص وظيفة
+
+109
+00:08:13,420 --> 00:08:18,580
+الأعضاء، إيش هي وظيفة الأعضاء؟ هو صحيح جدا أن أقول
+
+110
+00:08:18,580 --> 00:08:24,280
+أن هناك فصل بين ال structure و بين ال function،
+
+111
+00:08:24,280 --> 00:08:29,910
+العين في وظيفتها المتشورطيب، لازم أعرف إيش هي
+
+112
+00:08:29,910 --> 00:08:34,370
+العين، إيش تركيبة العين، كيف بتحقيق عملية الرؤية،
+
+113
+00:08:34,370 --> 00:08:38,850
+طبعا؟ الإيد وظيفتها إمكانية الوصول للأشياء، طب كيف
+
+114
+00:08:38,850 --> 00:08:42,930
+لازم أعرف الـ structure؟ هي كلها عضمة واحدة، هي
+
+115
+00:08:42,930 --> 00:08:46,470
+مجموعة من الإضام والمفاصل، طب في عضلات، طب العضلات
+
+116
+00:08:46,470 --> 00:08:49,700
+هذه إيش بتعمل؟وظيفة الله طب انا لازم اعرف ان هذه
+
+117
+00:08:49,700 --> 00:08:52,100
+العضلة واش تركبتها واش طولها وان origin وان
+
+118
+00:08:52,100 --> 00:08:55,060
+insertion بعد هيك ال function تبعيتها كيف انا بدي
+
+119
+00:08:55,060 --> 00:08:57,760
+اعرفها اعرفها عن طريق الفيسيولوجيا او علم
+
+120
+00:08:57,760 --> 00:09:00,220
+الفيسيولوجيا طب العضلة هذه ايش بتفرق عن العضلة هذه
+
+121
+00:09:00,220 --> 00:09:03,200
+عضلة ربعية و هذه عضلة تنائية عضلة طويلة هذي عضلة
+
+122
+00:09:03,200 --> 00:09:06,360
+قصيرة هذي شكلها عاملة زي الريشة هذي شكلها طب و
+
+123
+00:09:06,360 --> 00:09:10,620
+بعدين كل واحدة بتقدم وظيفة تتناسب معاه يبقى انا
+
+124
+00:09:10,620 --> 00:09:14,040
+لازم ابقى عارفة ال anatomy عشان انا اقدر ادرس
+
+125
+00:09:14,040 --> 00:09:15,580
+الفيسيولوجيا
+
+126
+00:09:18,440 --> 00:09:21,280
+طيب نشوف الـ structural level of the organization
+
+127
+00:09:22,370 --> 00:09:29,690
+الحين بتتكلم عن الذرة والجزاء وكيف بتتكون هذا ال
+
+128
+00:09:29,690 --> 00:09:34,510
+body كامل تبدأ من أشياء صغيرة جدا تتحد مع بعضها
+
+129
+00:09:34,510 --> 00:09:38,010
+تصير أكبر شوية تتحد مع بعضها تصير أكبر أكتر تتحد
+
+130
+00:09:38,010 --> 00:09:41,870
+مع بعضها تصير مجموعة من ال من ال من ال cells اللي
+
+131
+00:09:41,870 --> 00:09:45,130
+هي متشابهة بتعمل ال tissue مجموعة من ال tissues
+
+132
+00:09:45,130 --> 00:09:48,970
+متشابهة بتعمل ال organ مجموعة من ال organs بتعمل
+
+133
+00:09:48,970 --> 00:09:55,500
+الالـ body هذا أو ال systems ال systems كلها
+
+134
+00:09:55,500 --> 00:10:02,420
+بتعملي ال body و هنشوفهم واحدة واحدة ال atom زي ال
+
+135
+00:10:02,420 --> 00:10:08,120
+carbon ال hydrogen ال oxygen ال atom the smallest
+
+136
+00:10:08,120 --> 00:10:13,480
+the smallest أصغر واحدة particle of an element
+
+137
+00:10:13,480 --> 00:10:19,040
+atom combinedwith or react مع other atom اتنين اتم
+
+138
+00:10:19,040 --> 00:10:24,140
+او اكثر بيعمللي حاجة اسمها molecule الموليكول اللي
+
+139
+00:10:24,140 --> 00:10:27,620
+هتطلعني من ال carbon لحاله صار عندي carbon dioxide
+
+140
+00:10:27,620 --> 00:10:32,480
+تاني اكسيد الكربون صار عندي H2O اللي هو ال water
+
+141
+00:10:32,480 --> 00:10:36,600
+تمام؟ هذه ال molecules defined as particle
+
+142
+00:10:36,600 --> 00:10:41,130
+composed of two or morejoined atom يعني فى عندي
+
+143
+00:10:41,130 --> 00:10:45,410
+ذرتين اتحدوا فعمله منى عمله الجزاء اللى هو صار اشى
+
+144
+00:10:45,410 --> 00:10:51,750
+تانى مختلف الهيدروجين لحاله مع الكرباء مع ال .. مع
+
+145
+00:10:51,750 --> 00:10:55,810
+الاكسوجين كان هذا لحاله و هذا لحاله غازين مختلفين
+
+146
+00:10:55,810 --> 00:11:02,130
+لما اتحدوا مع بعض اعمله مية فصار فى عنديجزائي، طيب
+
+147
+00:11:02,130 --> 00:11:05,050
+الجزائي لو كان كبري شوية زي الـ carbon،
+
+148
+00:11:05,050 --> 00:11:08,230
+الـdehydrate أو الـ lipid أو البروتين، اللي هو
+
+149
+00:11:08,230 --> 00:11:15,770
+البروتينات والدهون، كل هذهعبارة عن ايش؟ Large
+
+150
+00:11:15,770 --> 00:11:20,810
+molecule، موليكول بس ايش، اكبير، ال macro
+
+151
+00:11:20,810 --> 00:11:24,610
+molecules combined with others، macro molecules،
+
+152
+00:11:24,610 --> 00:11:27,270
+كلهم بتحضر مع بعض عشان يعملول ال organelle، ال
+
+153
+00:11:27,270 --> 00:11:31,740
+organelle أقل من الcellالتي زي الـ cell membrane
+
+154
+00:11:31,740 --> 00:11:36,040
+للميوكلياس الريبوسومس هي defined as the small
+
+155
+00:11:36,040 --> 00:11:40,300
+organ of the cell organelle هي اسم ال organ of the
+
+156
+00:11:40,300 --> 00:11:43,600
+cell هاي ال cell which perform a particular
+
+157
+00:11:43,600 --> 00:11:48,320
+function ال organelle بتحدوا مع بعض فبيعملولي حاجة
+
+158
+00:11:48,320 --> 00:11:53,660
+اسمهاالـ Cell، الـ Cell هذه بتبدأ تتغير أو بتبدأ
+
+159
+00:11:53,660 --> 00:11:59,880
+تاخد نمط معين أو شكل معين أو خصائص معينة عشان تقدي
+
+160
+00:11:59,880 --> 00:12:04,760
+وظيفة اتحدت مع بعضها بتعمل لـ tissue في بعض الـ
+
+161
+00:12:04,760 --> 00:12:09,960
+cells المستقلة بذاتها زي الـ RBCs أو الـ Red Blood
+
+162
+00:12:09,960 --> 00:12:14,090
+CellsDefined as the basic unit of the structure
+
+163
+00:12:14,090 --> 00:12:18,530
+and function of living organisms هي الخلية
+
+164
+00:12:18,530 --> 00:12:27,480
+الأساسية ال basic unit اللي بتعمل بتحددش شكلتعمل
+
+165
+00:12:27,480 --> 00:12:33,500
+شكل عشان تحدد هي وين، هي خلية عصبية ولا خلية ..
+
+166
+00:12:33,500 --> 00:12:40,600
+خلية قلب ولا هي خلية اتحاد هيعمللي ال muscle أو
+
+167
+00:12:40,600 --> 00:12:47,630
+خلية هذه اتحاد هيعمللي ال ball أو غيريبقى بعض ال
+
+168
+00:12:47,630 --> 00:12:52,290
+cells have all the machinery that they need to
+
+169
+00:12:52,290 --> 00:12:59,170
+live يعني بتعيش مستقلة زي ال RBCs هي لها وظيفة
+
+170
+00:12:59,170 --> 00:13:06,230
+مستقلة ان هي بتحمل ال oxygen او transport ال
+
+171
+00:13:06,230 --> 00:13:11,820
+oxygenطبعا مجموعة من ال cells طبعا نقول مجموعة من
+
+172
+00:13:11,820 --> 00:13:16,260
+ال cells زي ال RBCs و ال white blood cells و ال
+
+173
+00:13:16,260 --> 00:13:21,560
+plasma بيكوّل الدم مع بعض مش لحالها ال RBCs طيب لو
+
+174
+00:13:21,560 --> 00:13:25,400
+اتكلمنا على مجموعة من ال neurons اللي هي ال cell
+
+175
+00:13:25,400 --> 00:13:29,800
+الخاصة بالجهاز العصبي فهي بتهتعمل مجموعة من ال
+
+176
+00:13:29,800 --> 00:13:32,740
+cells بتعمل ال tissue الخاصة بالجهاز العصبي اللي
+
+177
+00:13:32,740 --> 00:13:38,240
+بعدين بتهتعمل الجهاز العصبي المتكاملالخلايا زي الـ
+
+178
+00:13:38,240 --> 00:13:41,020
+epithelial و ال connective tissue و ال muscle و ال
+
+179
+00:13:41,020 --> 00:13:45,420
+nervous cells defined as a group of similar cells
+
+180
+00:13:45,420 --> 00:13:48,460
+that perform specialized function
+
+181
+00:13:51,620 --> 00:13:55,500
+العضلية تتحد مع بعض بتعمل ال tissue تبع العضلة
+
+182
+00:13:55,500 --> 00:14:01,360
+اللي هي بتشكل الحركة المسؤولة عن الحركة وها كذا
+
+183
+00:14:01,360 --> 00:14:05,320
+الخلايا العصبية مع بعض بتتحد بتعمل الجهاز العصبي
+
+184
+00:14:05,320 --> 00:14:11,540
+اللي هو المسؤول عن ال control تبع الجسم أو ال body
+
+185
+00:14:11,540 --> 00:14:17,640
+كله فالمجموعة السلها دي لما بتتحد بتعملي organ زي
+
+186
+00:14:17,640 --> 00:14:24,010
+ال skinخلايا ال skin غير عن خلايا حضارة القلب غير
+
+187
+00:14:24,010 --> 00:14:27,050
+عن الخلايا ال nervous system اللي بتكون ال brain
+
+188
+00:14:27,050 --> 00:14:31,570
+يبقى an organ is defined as the structure consists
+
+189
+00:14:31,570 --> 00:14:35,990
+of a group of tissue that perform specialized
+
+190
+00:14:35,990 --> 00:14:42,530
+functionطيب two organs لو اتكلمنا مثلا عن ال
+
+191
+00:14:42,530 --> 00:14:47,070
+gastro-intestinal بتبقى بالقناة الهضمية بيروح على
+
+192
+00:14:47,070 --> 00:14:51,190
+المعدة بيروح على ال intestines وبعدها بتصير عملية
+
+193
+00:14:51,190 --> 00:14:55,910
+الإخراج مجموعة من ال organs هذه عملت ال system
+
+194
+00:14:55,910 --> 00:15:01,170
+اللي هو اسمه الجهازSystem زي الـ Integumentary
+
+195
+00:15:01,170 --> 00:15:06,630
+اللي هو جهاز الخارجي أو الجلد ال cardiovascular
+
+196
+00:15:06,630 --> 00:15:10,790
+وغير واحنا بنعرف ال cardiovascular في عندنا القلب
+
+197
+00:15:10,790 --> 00:15:14,390
+و الدورة الدموية الصغرى و الدورة الدموية الكبرى
+
+198
+00:15:14,390 --> 00:15:17,910
+القلب بيوديالدم عن طريق دور دمائه الصغر على
+
+199
+00:15:17,910 --> 00:15:22,690
+الرئتين و بودد الدم عن طريق الأورطة على جميع أجزاء
+
+200
+00:15:22,690 --> 00:15:25,830
+الجسم و برجع بجيب الدم عن طريق ال infero superior
+
+201
+00:15:25,830 --> 00:15:29,410
+vena cava و عن طريق الأوراد الرئاوية الأربعة و
+
+202
+00:15:29,410 --> 00:15:32,830
+بصير في عندنا دم مأكثر و دم غير مأكثر و هذه كلها
+
+203
+00:15:32,830 --> 00:15:37,230
+اسمها system اسمه cardiovascular system احنا
+
+204
+00:15:37,230 --> 00:15:43,320
+تقريبا عندناorgan system موجودين في ال body هدول
+
+205
+00:15:43,320 --> 00:15:46,840
+ال 11 system مع بعض بيكونوا الهيئة اللي احنا
+
+206
+00:15:46,840 --> 00:15:52,980
+شايفينها هذه من الجسد وما خلينا نقول العظام اللي
+
+207
+00:15:52,980 --> 00:15:57,280
+بتاكسوها اللحم اللي بياكسوها الجلد ال internal
+
+208
+00:15:57,280 --> 00:16:01,100
+organs كلها اللي بتنظم عملية اللي في عندنا كبد وفي
+
+209
+00:16:01,100 --> 00:16:04,460
+عندنا طحال وفي عندنا في عندنا قناهادية وملاحقة
+
+210
+00:16:04,460 --> 00:16:10,810
+قناهادمية في عندنا رئتين وفي عندنا تراكياكل هذه ال
+
+211
+00:16:10,810 --> 00:16:14,930
+systems موجودة في ال body عشان تكون الهيئة العامة
+
+212
+00:16:14,930 --> 00:16:17,850
+اللي احنا بنشوفها هذه و بتقدي لل function اللي
+
+213
+00:16:17,850 --> 00:16:24,170
+احنا بنقديها هذا شخص متكامل انسان human being طبعا
+
+214
+00:16:24,170 --> 00:16:28,190
+فيالتقسيمة تانية عموما نتكلم أنه كل مجموعة من
+
+215
+00:16:28,190 --> 00:16:32,370
+الناس بيعملوا مجتمع population و ال population
+
+216
+00:16:32,370 --> 00:16:35,910
+هدول بيعملوا مجتمع و بيعملوا نظام اقتصادي و
+
+217
+00:16:35,910 --> 00:16:39,810
+بيعملوا نظام .. هذه كلها لما مجموعة الأفراد يعني
+
+218
+00:16:39,810 --> 00:16:43,370
+لإن إحنا في الشرق الأوسط إحنا بيسمونا شرقيين إحنا
+
+219
+00:16:43,370 --> 00:16:47,650
+مسلمين و هدولة مسيحية إحنا اليهود مثلا كل
+
+220
+00:16:47,650 --> 00:16:51,890
+المجموعات هذه بتتشابه في الصفات و بتكون عرق أو
+
+221
+00:16:51,890 --> 00:16:55,870
+بتكون community أو بتكوننظام اقتصادي زي الاتحاد
+
+222
+00:16:55,870 --> 00:17:01,610
+الأوروبي زي الامريكا ال united states ال united
+
+223
+00:17:01,610 --> 00:17:10,150
+emirates كلها هذه أنظمة اقتصادية و دول طيب هاي
+
+224
+00:17:10,150 --> 00:17:15,210
+الرسم التوضيحي ببسط العملية بقولنا كيف بتبدأ من
+
+225
+00:17:15,210 --> 00:17:19,650
+اتحادات ال atoms عشان نروح ل ال molecules مجموعة
+
+226
+00:17:19,650 --> 00:17:25,580
+ال molecules ايش بتعمل هي بتكون ل ال muscleبتكون
+
+227
+00:17:25,580 --> 00:17:32,100
+ال smooth tissues بتكون organ مجموعة ال organs
+
+228
+00:17:32,100 --> 00:17:41,080
+بتعملي ash ال living body زي هاي التفلة طبعا هاي
+
+229
+00:17:41,080 --> 00:17:50,740
+التفلة فيها بتمثل ال body تبعت الإنسان ال
+
+230
+00:17:50,740 --> 00:17:55,820
+body systems هنا باختصارال 11 اللي احنا اتكلمنا
+
+231
+00:17:55,820 --> 00:18:03,480
+عنهم، هنتكلم عنهم شوية زي .. مش عارف من اين ابدأ
+
+232
+00:18:03,480 --> 00:18:09,040
+انانبدأ من الـ Integumentary System اللي هو السطحي
+
+233
+00:18:09,040 --> 00:18:14,800
+الخارجي ال skeletal system ال muscular system ال
+
+234
+00:18:14,800 --> 00:18:19,300
+nervous system ال circulatory system ال endocrine
+
+235
+00:18:19,300 --> 00:18:22,560
+ال lymphatic ال digestive ال respiratory ال
+
+236
+00:18:22,560 --> 00:18:27,160
+urinary ال reproductive system هدولة مجموعة من ال
+
+237
+00:18:27,160 --> 00:18:32,160
+systems اللي بيكونوا ال body و هنتعرف عليهم one by
+
+238
+00:18:32,160 --> 00:18:36,830
+oneنبدأ في الـ Integumentary System احنا بنسميه هو
+
+239
+00:18:36,830 --> 00:18:42,410
+خط الدفاع الأول عن جسم الإنسان أول حاجة احنا
+
+240
+00:18:42,410 --> 00:18:47,190
+بتصيبنا بنقول I من وين أخدنا المستقبلات هذه موجودة
+
+241
+00:18:47,190 --> 00:18:51,590
+في ال skin ابنان الجرح الجرح البسيط قد يؤدي أحيان
+
+242
+00:18:51,590 --> 00:18:56,310
+إلى بطر في أصبع بطر في القدم ليه؟ لأن هو جرح صغير
+
+243
+00:18:56,310 --> 00:19:02,040
+مع ضيابة كفوت معلغس خلينا نقول if circulation في
+
+244
+00:19:02,040 --> 00:19:06,000
+المكان ممكن أو infection أو gangrene أو whatever
+
+245
+00:19:06,000 --> 00:19:12,280
+هذا بس بدأ في ال skinالـ regulatory system هو
+
+246
+00:19:12,280 --> 00:19:16,700
+عبارة عن ال skin ال hairs و ال nails طب ال skin
+
+247
+00:19:16,700 --> 00:19:20,440
+فيه إحساس ال hair مش فيها إحساس ال nails مش فيها
+
+248
+00:19:20,440 --> 00:19:24,680
+إحساس ليش؟ ربنا خلق الأدافير مش فيها إحساس عشان
+
+249
+00:19:24,680 --> 00:19:28,080
+نقدر نقصفها تخيلوا إن لو كلنا بدنا نقصف إجرينا
+
+250
+00:19:28,080 --> 00:19:31,660
+إيدينا أو أدافير إيدينا أو أدافير إجرينا بدنا نصير
+
+251
+00:19:31,660 --> 00:19:35,140
+نصيط أو بدنا نمغنع عن تقصيفة أو كل ما حد مسيكي
+
+252
+00:19:35,140 --> 00:19:38,120
+مقصه عمله في شعر و هك بدنا نصير نصرح معناه الناس
+
+253
+00:19:38,120 --> 00:19:41,800
+بتبقى ماشيةبقى دافير طويلة و أشعار طويلة لكن ال
+
+254
+00:19:41,800 --> 00:19:45,940
+skin هذا هذا المنبه على طول أول ما بينضغط أو
+
+255
+00:19:45,940 --> 00:19:51,160
+بتسيبه لسه قعدت بوس شكة أي إشي فالإنسان بيتنبع
+
+256
+00:19:51,160 --> 00:19:55,700
+فورا external covering كمان بيعطيني صورة جمالية
+
+257
+00:19:55,700 --> 00:20:00,360
+للجسم بيغطي كل أجزاء الجسم ال underlying tissue
+
+258
+00:20:00,360 --> 00:20:06,500
+organs كمان بيعطيني protection بيحفظ
+
+259
+00:20:07,180 --> 00:20:11,680
+تصنيع الفيتامين دي و المهم لو أضائف الجسم و ال
+
+260
+00:20:11,680 --> 00:20:15,620
+sense receptors اللي بتخلينا على طول نحس و بتعطينا
+
+261
+00:20:15,620 --> 00:20:20,340
+ال flash على طول ان انا دعست مثلا على مصمار في هنا
+
+262
+00:20:20,340 --> 00:20:27,060
+سخرة هنا فيه دبوس انا الجزمة ضيقة انجرحت مسكت
+
+263
+00:20:27,060 --> 00:20:31,800
+السكينة و أنا بقطع السلطة و صار في عندي جروح و
+
+264
+00:20:31,800 --> 00:20:37,170
+هكذانروح للـ skeletal system اللي هو الـ bone و ال
+
+265
+00:20:37,170 --> 00:20:41,510
+joints و ال cartilage هي منظومة لحالها بتعطين
+
+266
+00:20:41,510 --> 00:20:46,290
+الشكل الخارجي تبع الجسم بتعطيني support كمان
+
+267
+00:20:46,290 --> 00:20:50,210
+protection تساعد على الحركة أنا بتتحرك عن طريق إيش
+
+268
+00:20:50,210 --> 00:20:53,550
+تحريك الإضام اللي بتتحركها ال musculoskeletal ال
+
+269
+00:20:53,550 --> 00:20:56,890
+muscular system اللي بدنا نتكلم عنه بتعطيني blood
+
+270
+00:20:56,890 --> 00:21:00,810
+vessels كمان بتعمل production لل bloodالـ cells
+
+271
+00:21:00,810 --> 00:21:04,290
+الموجودة عن طريق الـ bone marrow الـ mineral
+
+272
+00:21:04,290 --> 00:21:08,450
+storage بتخزن الـ skeletal system بيخزن كل ال
+
+273
+00:21:08,450 --> 00:21:13,450
+mineral زي الكالسوم و الفوسفات في داخل العثقة أما
+
+274
+00:21:13,450 --> 00:21:16,490
+ال muscular system اللي بيعطي الهيئة كده للجسم
+
+275
+00:21:16,490 --> 00:21:21,250
+تصير الجسم يعني احنا بتطلع على شخص بدين أو شخص
+
+276
+00:21:21,250 --> 00:21:24,830
+ضعيف الشخص الضعيف هو كأنك بتشوفه عدم و متحرك الشخص
+
+277
+00:21:24,830 --> 00:21:28,170
+البدين بتشوفهفي خاصة لو كان رياضي وفي العضلات
+
+278
+00:21:28,170 --> 00:21:32,750
+بتشوف الشكل اللي عام تبعد يعني بيرمز كده للقوة لأن
+
+279
+00:21:32,750 --> 00:21:37,610
+عضلاته قوية شديدة أعطت الشكل تبع الفسم العضلات هي
+
+280
+00:21:37,610 --> 00:21:42,990
+اللي بيسموها اللحمةهي عبارة عن العضلات الاسكليطة
+
+281
+00:21:42,990 --> 00:21:46,490
+المصرية اللي associated connective tissue سيتندن
+
+282
+00:21:46,490 --> 00:21:50,730
+العضلات تطلع البياد اللي موجود هنا هذا البياد كله
+
+283
+00:21:50,730 --> 00:21:54,990
+connective connective tissue على أساس أنها توصل
+
+284
+00:21:54,990 --> 00:22:00,290
+هالمنظومة هذه مع بعضهاالـ functional locomotion،
+
+285
+00:22:00,290 --> 00:22:03,590
+الحركة والانتقال، الـ manipulation of the
+
+286
+00:22:03,590 --> 00:22:06,890
+environment، فيعني أنا لما بدي أجي أزيح الكرسي،
+
+287
+00:22:06,890 --> 00:22:09,710
+بدي عضلات، بدي أزيح المكتب، بدي عضلات، بدي أحرك
+
+288
+00:22:09,710 --> 00:22:14,200
+الماوس، بدي عضلات، بدي أمشي، بدي عضلاتطبعا احنا
+
+289
+00:22:14,200 --> 00:22:16,840
+نطلع ال facial expressions كلها اللي بيعمل العمل
+
+290
+00:22:16,840 --> 00:22:21,660
+ال facial expressions مكشرين مبتسمين كل ال facial
+
+291
+00:22:21,660 --> 00:22:26,760
+expressions هذه بتقديها العضلات طبعا بتحافظ على ال
+
+292
+00:22:26,760 --> 00:22:29,620
+position احنا نشوف ناس كتير محطبين في ناس بتلاقي
+
+293
+00:22:29,620 --> 00:22:33,520
+مستهجش position في ناس لأ مهضين والله هم رتبين
+
+294
+00:22:33,520 --> 00:22:38,480
+وكمان الحركة عن طريقالعضلات بتعطيني heat
+
+295
+00:22:38,480 --> 00:22:41,920
+production، عشان heat production بتدفّي، يعني احنا
+
+296
+00:22:41,920 --> 00:22:45,000
+بنلاحظ احنا اول ما بنبرد بنبدأ نفرّك في اديانا،
+
+297
+00:22:45,000 --> 00:22:48,560
+بنبدأ نمط، بنبدأ نعمل رياضة عشان إيه؟ عشان نحرك
+
+298
+00:22:48,560 --> 00:22:53,480
+هالطاقة الكامية اللي موجودة و بالعربي ندفّيهو ال
+
+299
+00:22:53,480 --> 00:22:57,200
+circulatory system فهو ال cardiovascular system و
+
+300
+00:22:57,200 --> 00:22:59,980
+ال lymphatic system ايش وظيفتهم ال transportation
+
+301
+00:22:59,980 --> 00:23:03,760
+يعني وسيلة المواصلات للدم هي بتكون عبارة عن
+
+302
+00:23:03,760 --> 00:23:09,660
+القنوات اللي هي الموجودة في ال vascular system و
+
+303
+00:23:09,660 --> 00:23:12,340
+ال lymphatic systemfor the photomatransportation
+
+304
+00:23:12,340 --> 00:23:15,580
+of minerals within the body بتوزع المواد الغذائية
+
+305
+00:23:15,580 --> 00:23:20,620
+هذه على ال body وكمان to and from internal and
+
+306
+00:23:20,620 --> 00:23:23,980
+external environment طيب احنا في عندنا ال internal
+
+307
+00:23:23,980 --> 00:23:28,260
+environment وفي عندنا ال external environment عن
+
+308
+00:23:28,260 --> 00:23:34,620
+طريقها احنا ممكن ننظم الجسم الانسان ال
+
+309
+00:23:34,620 --> 00:23:42,540
+cardiovascular system زي ال heartوالـ blood
+
+310
+00:23:42,540 --> 00:23:48,060
+vessels function transportation of the blood البلد
+
+311
+00:23:48,060 --> 00:23:52,460
+عادة بيكون فيه بيحمل أكسوجين و ثاني أكسيد الكربون
+
+312
+00:23:54,420 --> 00:23:58,100
+احنا بناخد مفس و بناخد أكسجين و بنطلع و بنطلع ثاني
+
+313
+00:23:58,100 --> 00:24:02,000
+أكسيد الكربون كيف بتصير هذه العملية هنشرحها في
+
+314
+00:24:02,000 --> 00:24:06,560
+وقتها ال nutrients أو المواد الغذائية ال waste
+
+315
+00:24:06,560 --> 00:24:09,820
+product كيف بتطلع كلها عن طريق ال cardiovascular
+
+316
+00:24:09,820 --> 00:24:16,650
+system ال blood is composed of plasma and cellsالـ
+
+317
+00:24:16,650 --> 00:24:19,470
+lymphatic طبعاً الـ lymphatic organs زي الـ spleen
+
+318
+00:24:19,470 --> 00:24:23,330
+و الـ lymph nodes و الـ thymus، lymphatic vessels
+
+319
+00:24:23,330 --> 00:24:27,950
+كلها برفتها transportation of the lymph، lymph is
+
+320
+00:24:27,950 --> 00:24:34,570
+divided، derived، بيجي من ال tissue، ال fluid و ال
+
+321
+00:24:34,570 --> 00:24:39,730
+white، موجود في ال white blood cells عشان تعزز
+
+322
+00:24:39,730 --> 00:24:43,590
+جهاز المناعة اللي احنا بنتكلم عنه اللي هو ال
+
+323
+00:24:43,590 --> 00:24:48,640
+immune systemالـ component of immune system الـ
+
+324
+00:24:48,640 --> 00:24:52,140
+immune organ الـ bone marrow و الـ thymus ال white
+
+325
+00:24:52,140 --> 00:24:55,400
+blood cells ال lymphocytes بنسميها و ال macro
+
+326
+00:24:55,400 --> 00:25:01,140
+phages اللي هي الخلايا الأكلة هذه اللي بتساعد على
+
+327
+00:25:01,140 --> 00:25:08,140
+ال phagocytosis ال function defense دفاع بس الدفاع
+
+328
+00:25:08,140 --> 00:25:11,960
+و احنا خط دفاع الأول قلنا ال skin لكن ال immune
+
+329
+00:25:11,960 --> 00:25:17,660
+system هو اللي بدي هاجم أيبكتيريا، أي فيروس، أي
+
+330
+00:25:17,660 --> 00:25:23,040
+إشي خارجي نظام المنظومة اللي هو الطبيعي أو ال
+
+331
+00:25:23,040 --> 00:25:26,780
+normal اللي موجود في الجسم على طول بيعمل دفعات
+
+332
+00:25:27,960 --> 00:25:31,920
+بتبدأ الغدّة اللي هي thymus، gland تشغل على أساس
+
+333
+00:25:31,920 --> 00:25:39,460
+أنها تحفز المناعة و تهاجم كل الخلايا هذه اللي هجمت
+
+334
+00:25:39,460 --> 00:25:42,780
+الجسم و تقضي عليها و لو صار خلل في جهاز المناعة
+
+335
+00:25:42,780 --> 00:25:47,600
+ممكن يصير يأكل بعضه يعني يأكل المنيح والسيئ من
+
+336
+00:25:47,600 --> 00:25:51,720
+الخلايا وهذا بيبقى إشي مرضي أما ال nervous system
+
+337
+00:25:51,720 --> 00:25:57,170
+وظيفته ال control في عندنا اتنينأساسيا من مكونات
+
+338
+00:25:57,170 --> 00:25:59,790
+ال nervous system عنا ال central nervous system و
+
+339
+00:25:59,790 --> 00:26:03,850
+ال peripheral ال central عبارة عن ال spinal cord و
+
+340
+00:26:03,850 --> 00:26:07,730
+ال brain و ال peripheral عبارة عن ال nerve و ال
+
+341
+00:26:07,730 --> 00:26:14,010
+receptors اللي موجودة في الجسم وضيفته control fast
+
+342
+00:26:14,010 --> 00:26:21,370
+hard wiredأول حاجة أنا بتعرضلها إجا حد بده يوقعني
+
+343
+00:26:21,370 --> 00:26:24,830
+على طول أنا بنتبه، بمسك إيده أو برفع إيدي بهذا
+
+344
+00:26:24,830 --> 00:26:28,610
+الشكل، حطيت إيدي وحملت .. مسكت ال microwave مثلا
+
+345
+00:26:28,610 --> 00:26:33,480
+طلعت كباية أو صحمة سخن برميهدعست على مصمار برفع
+
+346
+00:26:33,480 --> 00:26:38,280
+رجلي، اتعرضت لخطر معين بخاف أو بشد على جسمي و هكذا
+
+347
+00:26:38,280 --> 00:26:42,980
+Respond to external and internal environments طبعا
+
+348
+00:26:42,980 --> 00:26:46,040
+بيجيه الإحساس في ال external environment طب كيف بي
+
+349
+00:26:46,040 --> 00:26:48,380
+respond to the external environment؟ بيجيه الإحساس
+
+350
+00:26:48,380 --> 00:26:51,340
+أنا لقيتها قاعدة في التكييف حاسة الجو بارد، طلعت
+
+351
+00:26:51,340 --> 00:26:56,030
+برا بحسه حامل، والله الجو بارد كتير، تلجبحس هذا
+
+352
+00:26:56,030 --> 00:26:58,990
+اجتني من احمل امسكت اشي سخن هذا external
+
+353
+00:26:58,990 --> 00:27:03,310
+environment بتيجي انا لجسمي اما ال endocrine
+
+354
+00:27:03,310 --> 00:27:08,830
+systemطبعا المسئول عن ال control السريع اللي هو ال
+
+355
+00:27:08,830 --> 00:27:11,650
+nervous system على ال control البطيء اللي هو ال
+
+356
+00:27:11,650 --> 00:27:14,550
+endocrine system اللي هو عبارة عن ال gland to
+
+357
+00:27:14,550 --> 00:27:18,990
+secret that secretes hormones ال hormones هذه هي
+
+358
+00:27:18,990 --> 00:27:23,070
+اللي بتنظم الجسم تسيسي الغدد المختلفة ال pituitary
+
+359
+00:27:23,070 --> 00:27:27,550
+ال pancreas الthyroid اللي بيسموه الغدد القدرية و
+
+360
+00:27:27,550 --> 00:27:31,750
+القدرية و ال pancreas اللي بيفرزلي هرمون الانسولين
+
+361
+00:27:31,750 --> 00:27:36,020
+و هكذاأما الـ Function هي الـ Slow Chemicals اللي
+
+362
+00:27:36,020 --> 00:27:39,160
+هي ترددت الفعل السريع يحنا بناخدهم ال nervous
+
+363
+00:27:39,160 --> 00:27:42,620
+system أما الرددت الفعل البطيقة اللي هي بتعمل
+
+364
+00:27:42,620 --> 00:27:47,640
+تنظيم لبيئة الجسم أو بتحافظ على ال homogenous أو
+
+365
+00:27:47,640 --> 00:27:53,060
+ال homostasis و ال homostasis هو عبارة عن ال
+
+366
+00:27:53,060 --> 00:27:56,960
+endocrine system regulates ال process such as a
+
+367
+00:27:56,960 --> 00:28:00,920
+growth reproductive and nutrient uses
+
+368
+00:28:02,740 --> 00:28:05,420
+Respiratory System هو عبارة عن الـ Lung و كل الـ
+
+369
+00:28:05,420 --> 00:28:08,760
+Tube زي التراكيا و الـ Pancreas و غيره و الـLarynx
+
+370
+00:28:08,760 --> 00:28:12,080
+اللي هي ال vocal cord اللي هي عبارة عن الحنجرة
+
+371
+00:28:12,080 --> 00:28:16,500
+اللي موجودة فيها الـ Voice Box اللي بيخلنا نقدر
+
+372
+00:28:16,500 --> 00:28:21,710
+نصدر هذه الأصواتطبعا إيش؟ وظيفة ال lungs اللي هي
+
+373
+00:28:21,710 --> 00:28:25,190
+exchange of respiratory gases الأكسجين، يعني احنا
+
+374
+00:28:25,190 --> 00:28:30,350
+بناخد نفس بناخد الأكسجين و بناخد منه ثاني أكسيد
+
+375
+00:28:30,350 --> 00:28:33,930
+الدم بيمر، بياخد الأكسجين من ال alveoli و بيعطيها
+
+376
+00:28:33,930 --> 00:28:38,300
+ثاني أكسيد الكربونهذه عملية الشغيق أما الـ Zephyr
+
+377
+00:28:38,300 --> 00:28:41,680
+فإحنا بناخد ثاني أكسيد الـ Carbon الـ Voice
+
+378
+00:28:41,680 --> 00:28:44,400
+Production إحنا لما بنتكلم لازم يكون فيه يعني
+
+379
+00:28:44,400 --> 00:28:47,740
+نلاحظ أن الناس بتبقى عاملة تركز ثم هنا في الفتحة
+
+380
+00:28:47,740 --> 00:28:51,580
+في القصة اللوائية ما بيطلع صوتها لأن الهواء
+
+381
+00:28:51,580 --> 00:28:58,090
+وترددات الهواء ماوصلت للأحبال الصوتيةال digestive
+
+382
+00:28:58,090 --> 00:29:01,870
+system هو الجهاز الهضمي فيه ال alimentary canal زي
+
+383
+00:29:01,870 --> 00:29:05,010
+ال mouth، ال pharynx، ال oesophagus، في عندنا قناة
+
+384
+00:29:05,010 --> 00:29:09,110
+بنسميها القناة الهضمية وفي عندنا اللي هي ملحقات
+
+385
+00:29:09,110 --> 00:29:13,030
+الجهاز الهضمي زي الكبد، ال liver، saliva gland، ال
+
+386
+00:29:13,030 --> 00:29:16,450
+pancreas، هذه بنسميها ال spleen، كلها ملحقات
+
+387
+00:29:16,450 --> 00:29:20,270
+الجهاز الهضمي و the feta break down the food into
+
+388
+00:29:20,270 --> 00:29:25,230
+smallerobject عشان نقدر احنا نعمله absorption و
+
+389
+00:29:25,230 --> 00:29:30,910
+نستفيد من المواد الغذائية اللي احنا بناخدها اثناء
+
+390
+00:29:30,910 --> 00:29:34,610
+من الطعام اللي احنا بناخده الشراب ال absorption
+
+391
+00:29:34,610 --> 00:29:38,430
+عشان تروح لل blood و تروح على أجهزة في الجسم
+
+392
+00:29:38,430 --> 00:29:43,770
+المختلفة و كمان حتى نتخلص من ال waste productيعني
+
+393
+00:29:43,770 --> 00:29:47,330
+متخيلين انه احنا لو جسمنا بس بيدخله السموم هذه
+
+394
+00:29:47,330 --> 00:29:50,390
+بتبقى لها في جسمنا كيف بيكون وضعنا لو صار فيه
+
+395
+00:29:50,390 --> 00:29:53,630
+مشكلة، لو على الأقل يعني .. يعني upset بقاش ال
+
+396
+00:29:53,630 --> 00:29:58,150
+constipation، بتحجر ال stool، روات، ال intestine،
+
+397
+00:29:58,150 --> 00:30:03,000
+وما بيقدر الإنسان يخرجه؟نجلال الورينري سيستم اللي
+
+398
+00:30:03,000 --> 00:30:07,620
+هو بتكون من الكدني و الوريتارز و الورينري بلدر و
+
+399
+00:30:07,620 --> 00:30:11,580
+الوريثرا هدولة مكونات الورينري ترات اللي بيساعدنا
+
+400
+00:30:11,580 --> 00:30:16,620
+على التخلص من السموم عن طريق تنقيتها بواسطة
+
+401
+00:30:16,620 --> 00:30:20,920
+الكليتين eliminate was زي ال nitrogen from the
+
+402
+00:30:20,920 --> 00:30:24,880
+blood between blood and external environment
+
+403
+00:30:26,940 --> 00:30:33,560
+regulate water electrolyte acid base balance بينظم
+
+404
+00:30:33,560 --> 00:30:42,400
+كل مكونات الدم عن طريق ال urinary system ال
+
+405
+00:30:42,400 --> 00:30:47,720
+reproductive هو عبارة عن إيش؟ هو عبارة عن المحافظة
+
+406
+00:30:47,720 --> 00:30:52,680
+على الحياة و عن استمرارية الحياة التكاثر خلينا
+
+407
+00:30:52,680 --> 00:30:56,610
+نقول فيه أنالـ Male Reproductive System والـ
+
+408
+00:30:56,610 --> 00:31:00,990
+Female Reproductive System وظيفتهم بـ Reproduction
+
+409
+00:31:00,990 --> 00:31:06,670
+of the Species المحافظة ده خلينا نقول على الكون،
+
+410
+00:31:06,670 --> 00:31:12,690
+الإنتاج الهرمون Influence Structure and Function
+
+411
+00:31:12,690 --> 00:31:18,370
+طبعاً فيه إنه هرمونات خاصة بجهاز التناثل الأمطوي
+
+412
+00:31:18,370 --> 00:31:22,670
+والذكري Sexual Demo
+
+413
+00:31:23,520 --> 00:31:29,460
+morphic spaces بيساعد في عملية ال sexual،
+
+414
+00:31:29,460 --> 00:31:33,860
+العلاقات، خليني أقول الجنسية اللي بينتج عنها ال
+
+415
+00:31:33,860 --> 00:31:37,700
+reproduction أو إنتاج الإنسان أو التكاثر، خليني
+
+416
+00:31:37,700 --> 00:31:42,790
+أسميه بـبهنا بنقدر احنا نوقف محاضرتنا لليوم لإن ما
+
+417
+00:31:42,790 --> 00:31:47,610
+في عندنا هنتقل لموضوع جديد هو ال anatomical
+
+418
+00:31:47,610 --> 00:31:53,050
+terminologies الخاصة بال Anatomy اللي كل شخص من ..
+
+419
+00:31:53,050 --> 00:31:59,490
+كل خريج من العلوم الصحية يجب أن يتعلمها أو يعلمها
+
+420
+00:31:59,490 --> 00:32:03,030
+أو يحفظها غيبا لإن هذه هتستمر معاه على السنوات
+
+421
+00:32:03,030 --> 00:32:06,250
+اللي أنا بتسهل عنينا عملية الحفظ و المتابعة
+
+422
+00:32:06,550 --> 00:32:10,530
+والدراسة ما بعد هيك، يعطيكم العافية والسلام عليكم
+
+423
+00:32:10,530 --> 00:32:11,190
+ورحمة الله
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM.srt
new file mode 100644
index 0000000000000000000000000000000000000000..aa5de44a8a0c8689633540fcb82ed7a46fc0de67
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM.srt
@@ -0,0 +1,1528 @@
+1
+00:00:05,010 --> 00:00:09,350
+بسم الله الرحمن الرحيم. لمحاضرتنا اليوم الثانية في
+
+2
+00:00:09,350 --> 00:00:15,290
+مساق الـ anatomy. المحاضرة السابقة، تعرّفنا عليها
+
+3
+00:00:15,290 --> 00:00:18,530
+بتعريف الـ anatomy والـ physiology. اليوم سنتعرف على
+
+4
+00:00:18,530 --> 00:00:21,550
+بعض الـ terminology اللي احنا عادةً بنستخدمها في
+
+5
+00:00:21,550 --> 00:00:24,950
+مجال الـ anatomy.  اللي بنرجوه منكم طبعاً كطلاب أن
+
+6
+00:00:24,950 --> 00:00:30,880
+شاء الله تكونوا حافظينها لآخر يوم في عمركم،  اللي
+
+7
+00:00:30,880 --> 00:00:35,640
+بالتخصص، بمعنى اللي بيشتغل في مجال المهن الصحية هذه
+
+8
+00:00:35,640 --> 00:00:39,640
+الـ terminology لازم يكون حافظها للأبد، واللي طبعاً
+
+9
+00:00:39,640 --> 00:00:43,280
+بيختار career  ثاني بعد ما يتخرج، هو حر يحفظ أو ما
+
+10
+00:00:43,280 --> 00:00:47,490
+يحفظ. هذا يرجع له. الـ anatomical terminology هذه مهمة
+
+11
+00:00:47,490 --> 00:00:50,790
+لأنها ستُبنى عليها كل المعلومات العملية والنظرية
+
+12
+00:00:50,790 --> 00:00:55,010
+اللي بدنا نتعلمها بعد هيك في مجال العلوم الصحية، و
+
+13
+00:00:55,010 --> 00:00:58,710
+يفضل أن نكون حافظينها by heart لأنها شغلات
+
+14
+00:00:58,710 --> 00:01:02,590
+أساسية. اليوم سيكون لدينا دور في فهمها وإدراكها،
+
+15
+00:01:02,590 --> 00:01:07,410
+لكنها تُحفظ حفظاً، وهي عبارة عن كلمات متكررة في
+
+16
+00:01:07,410 --> 00:01:12,450
+سياق الدراسات، إن شاء الله، في الفصول القادمة كلها
+
+17
+00:01:12,450 --> 00:01:16,390
+ستُسهل علينا عملية، لنقل، متابعة الدراسة، تُسهل
+
+18
+00:01:16,390 --> 00:01:21,410
+علينا عملية القراءة والإطلاع والفهم والإدراك، حتى لا
+
+19
+00:01:21,410 --> 00:01:26,250
+نضطرّ كل مرة نفسر المصطلحات هذه. اسمها مصطلحات لازم
+
+20
+00:01:26,250 --> 00:01:29,950
+أن نعرفها. وأعتقد أن في منكم أخذ مساق المصطلحات
+
+21
+00:01:29,950 --> 00:01:34,050
+الطبية. قد يكون مرّ عليه جزء منها، إلا أن في مجال
+
+22
+00:01:34,050 --> 00:01:37,930
+مساق الـ anatomy، ما نستطيع إلا أن نأخذ الـ
+
+23
+00:01:37,930 --> 00:01:40,350
+anatomical terminology التي سنتعرف عليها. أهم
+
+24
+00:01:40,350 --> 00:01:43,530
+شيء أن الـ anatomical position هو إذا كان، إن
+
+25
+00:01:43,530 --> 00:01:46,170
+شاء الله الكاميرا تُكشفني، هو هذا الوضع، أنه يقف
+
+26
+00:01:46,170 --> 00:01:51,470
+الشخص بهذا الشكل، الـ face forward، الـ hands
+
+27
+00:01:51,470 --> 00:01:55,810
+بالـ balance forward، والـ thumb للخارج، والأجرتين apart
+
+28
+00:01:55,810 --> 00:01:59,630
+طبعاً واضحة بالصورة، أن هذا اسمه anatomical position
+
+29
+00:01:59,630 --> 00:02:04,710
+يعني أي هو الـ reference لكلمّة مصطلح نحن نتكلم بعد
+
+30
+00:02:04,710 --> 00:02:09,270
+... نتكلم عنه في مجالاتنا المختلفة هو الـ ... الـ ...
+
+31
+00:02:09,270 --> 00:02:13,510
+الـ ... الـ position، الـ reference. يعني لما نتكلم عن
+
+32
+00:02:13,510 --> 00:02:17,410
+reflection، أنا أتحدث عن reflection من extended arm
+
+33
+00:02:17,410 --> 00:02:20,130
+بهذا الشكل. نتكلم من supination و antipronation
+
+34
+00:02:20,130 --> 00:02:24,310
+نتكلم من هذا، وكل المصطلحات هذه سنمر عليها خلال
+
+35
+00:02:24,310 --> 00:02:28,450
+محاضرتنا. طيب، يعني هي عبارة عن إيش؟ هو position
+
+36
+00:02:30,190 --> 00:02:35,810
+الشخص بيكون فيه واقف upright، الـ feet على الأرض، و
+
+37
+00:02:35,810 --> 00:02:39,390
+parallel و flat على الـ floor زي ما نحن شايفين
+
+38
+00:02:39,390 --> 00:02:46,030
+بالمنظر اللي قدامنا هذا. الـ hip بيكون على مستوى الـ
+
+39
+00:02:46,030 --> 00:02:51,770
+eyes،  تطلع لقدام، تطلع الشخص فيه forward، طبعاً كأنه
+
+40
+00:02:51,770 --> 00:02:55,990
+في أحد واقف قدامك ويتطلع عليك. دائماً يكون to the
+
+41
+00:02:55,990 --> 00:03:00,370
+side، الأرض زي ما نحن شايفين، الـ side of the body، و
+
+42
+00:03:00,370 --> 00:03:04,210
+بالطبع الـ face forward، والـ thumb الـ lateral
+
+43
+00:03:04,210 --> 00:03:09,770
+position. طبعاً في حاجة اسمها plans، إيش الـ plans؟ هي
+
+44
+00:03:09,770 --> 00:03:16,310
+عبارة عن مقاطع للجسم تُسهّل عملية تقسيم الجسم، و
+
+45
+00:03:16,310 --> 00:03:20,010
+الحركة، لأن الحركة تحدث في plane، في plan، يعني
+
+46
+00:03:20,010 --> 00:03:24,460
+في عندنا imaginary surface،  لا يُعطي cutting  لـ
+
+47
+00:03:24,460 --> 00:03:28,840
+الـ body، من خلال هذا الـ cut الذي يُعطيه يُمكننا
+
+48
+00:03:28,840 --> 00:03:32,240
+أن نفسر مثلاً حركة الـ flexion والـ extension
+
+49
+00:03:32,240 --> 00:03:35,700
+بيصبح  putsch plan،  مدان في أننا plan وفي أننا حركة
+
+50
+00:03:35,700 --> 00:03:40,180
+يبقى في أننا access للحركة. plan is an imaginary
+
+51
+00:03:40,180 --> 00:03:46,710
+surface that slices the body into specific sections
+
+52
+00:03:46,710 --> 00:03:51,970
+يُسمّى  للمقاطع، سواء مقاطع طولية أو مقاطع عرضية. طيب،
+
+53
+00:03:51,970 --> 00:03:54,830
+إيش الـ main plans التي نتكلم عنها؟ في
+
+54
+00:03:54,830 --> 00:03:57,670
+عندنا ثلاثة main plans، هي الـ coronal والـ transverse
+
+55
+00:03:57,670 --> 00:04:01,310
+والـ sagittal. الـ planes التي كل الحركة التي نحن
+
+56
+00:04:01,310 --> 00:04:07,190
+نتحركها تدور في هذولا الـ planes أو هذه الأسطح
+
+57
+00:04:07,190 --> 00:04:11,070
+التي نسميها التخيلية
+
+58
+00:04:13,190 --> 00:04:19,290
+طيب، الـ coronal plane هو عبارة عن plane يقسم الجسم
+
+59
+00:04:19,290 --> 00:04:25,150
+بمقطع بهذا الشكل، انقسام الجسم بهذا الشكل، يعني في
+
+60
+00:04:25,150 --> 00:04:29,810
+عندنا anterior وفي عندنا posterior surface، يعني
+
+61
+00:04:29,810 --> 00:04:34,570
+في عندنا أمام وفي عندنا خلف. لأن ننظر للشخص هو
+
+62
+00:04:34,570 --> 00:04:39,350
+قدامنا، ننظر إليه من أمام على الـ anterior plane فهو
+
+63
+00:04:39,350 --> 00:04:43,310
+يكون نظر عليه بالـ frontal plane، ولو نظرنا من الخلف فاحنا
+
+64
+00:04:43,310 --> 00:04:48,260
+نتكلم عن الـ back، فهو الـ posterior plane. أي مقطع في
+
+65
+00:04:48,260 --> 00:04:52,900
+الجسم بهذا الشكل، بهذا الشكل بيكون بيقطّعه، نسميه في
+
+66
+00:04:52,900 --> 00:04:58,820
+الـ coronal أو الـ frontal plane. أما الـ transverse وهو
+
+67
+00:04:58,820 --> 00:05:05,560
+المقطع الـ horizontal، بيقطّعه لنصفين، إما هو نصفين
+
+68
+00:05:05,560 --> 00:05:09,600
+على الأقل. دائماً لازم نص تحت ونص فوق، بس بياخدوا
+
+69
+00:05:09,600 --> 00:05:16,370
+من مقاطع مختلفة، طبعاً. إحنا لما نقطّع الجسم بهذا
+
+70
+00:05:16,370 --> 00:05:20,030
+الشكل، معناه الحركات التي تحدث حركات تقريباً تكون
+
+71
+00:05:20,030 --> 00:05:23,230
+بهذا الشكل، اللي هي الحركات الدورانية بهذا الشكل
+
+72
+00:05:23,230 --> 00:05:26,830
+أنا لما أشتغل بهذا الشكل، أنا أشتغل ملامسة لإيش؟
+
+73
+00:05:26,830 --> 00:05:33,090
+ملامسة للـ horizontal plane. طبعاً كل plane الحركة
+
+74
+00:05:33,090 --> 00:05:35,090
+تحدث فيه عن طريق axis
+
+75
+00:05:40,450 --> 00:05:44,970
+لما نتكلم هكذا، أنا لما أتحدث عن حركة بهذا الشكل، بهذا
+
+76
+00:05:44,970 --> 00:05:47,670
+الشكل، أنا الحركة التي تحدث في الـ horizontal plane
+
+77
+00:05:47,670 --> 00:05:52,190
+لا بد أن يكون عندي longitudinal axis بهذا الشكل، هكذا
+
+78
+00:05:52,190 --> 00:06:03,230
+وهكذا. ففي عندي axis يمرّ في طول، على طول الجسم. أنا
+
+79
+00:06:03,230 --> 00:06:09,900
+سأشرح الـ plane، فهو يقسم الجسم لجزئين طوليين، right and
+
+80
+00:06:09,900 --> 00:06:14,440
+left. لو كان ماشي في وسط الجسم، فهو يقسم الجسم
+
+81
+00:06:14,440 --> 00:06:17,220
+لجزئين متشابهين، as a mirror
+
+82
+00:06:37,720 --> 00:06:41,480
+يكون، يبقى في عندنا right side وفي عندنا left side
+
+83
+00:06:41,480 --> 00:06:48,140
+نسميه median plane لما يقسم الجسم لجزئين متساويين
+
+84
+00:06:48,140 --> 00:06:53,700
+left and right. طبعاً، ممكن يصير في عندنا sections
+
+85
+00:06:53,700 --> 00:06:57,240
+يعني،  ليس شرطاً أن يقسم الجسم من المنتصف، ممكن يقسمه
+
+86
+00:06:57,240 --> 00:07:01,260
+من هنا، من هنا، من هنا، من هنا، يأخذ مقاطع مختلفة، لما
+
+87
+00:07:01,260 --> 00:07:05,400
+يكون في المنتصف فهو يكون الـ mid-sagittal plane
+
+88
+00:07:08,290 --> 00:07:13,010
+مقطع لأجزاء غير متلاصقة، فنسميه الـ para-sagittal
+
+89
+00:07:13,010 --> 00:07:16,030
+يعني، المهم أن في عندنا left side وفي عندنا right
+
+90
+00:07:16,030 --> 00:07:21,430
+side. ما لم يكن oblique، لما يكون غير vertical الـ
+
+91
+00:07:21,430 --> 00:07:25,870
+axis، فتكون عندنا يكون عامل an angle، نسميه
+
+92
+00:07:25,870 --> 00:07:32,730
+oblique plane هنا
+
+93
+00:07:32,730 --> 00:07:38,970
+طبعاً، نحن عرفنا الـ three planes. أتمنى منكم كل
+
+94
+00:07:38,970 --> 00:07:45,720
+واحد يحاول أن يعمل الحركات ويقسم الحركات هذه التي في
+
+95
+00:07:45,720 --> 00:07:49,740
+الجسم على الـ planes الموجودة. سنتكلم عن الـ
+
+96
+00:07:49,740 --> 00:07:52,460
+movement لما نتكلم عن الـ musculoskeletal system، بس
+
+97
+00:07:52,460 --> 00:07:56,220
+بدنا نذكر الكلام، الكلام عن الـ plane والـ accesses
+
+98
+00:07:56,220 --> 00:07:59,540
+لأن يوم ما نتحدث عن الـ movement،  سنرجع لها
+
+99
+00:07:59,540 --> 00:08:04,260
+سنرجع لها بالتفصيل على أساس أن نعرف كل حركة، مثلاً
+
+100
+00:08:04,260 --> 00:08:07,260
+حركة flexion of the elbow، flexion and
+
+101
+00:08:07,260 --> 00:08:13,730
+extension، تحدث في أي plane؟  تحدث في مقطع، فتكون
+
+102
+00:08:13,730 --> 00:08:16,750
+الحركة في الـ sagittal plane، لكن الـ axis  سابقاً يكون
+
+103
+00:08:16,750 --> 00:08:22,050
+بهذا الشكل، في الـ frontal plane. الـ axis هذا يحتاج لشرح
+
+104
+00:08:22,050 --> 00:08:25,850
+تفاصيل، إن شاء الله، سأشرحه في وقته، لما نصل لـ
+
+105
+00:08:25,850 --> 00:08:29,430
+movements of the body في الـ musculoskeletal system
+
+106
+00:08:30,080 --> 00:08:33,580
+أما الـ directional terms، فنحن لازم نعرف إيش تعني
+
+107
+00:08:33,580 --> 00:08:36,680
+كلمة superior، إيش تعني كلمة inferior، إيش تعني
+
+108
+00:08:36,680 --> 00:08:40,360
+كلمة lateral، إيش تعني كلمة medial، abduction،
+
+109
+00:08:40,360 --> 00:08:44,260
+adduction، كل الألفاظ هذه سنتعرف عليها من خلال
+
+110
+00:08:44,260 --> 00:08:48,840
+المصطلحات القادمة
+
+111
+00:08:48,840 --> 00:08:52,560
+المصطلحات، دائماً في عندنا opposition، دائماً في
+
+112
+00:08:52,560 --> 00:08:56,760
+عندنا right، left، superior، inferior، abduction،
+
+113
+00:08:56,760 --> 00:09:03,100
+adduction،  سنرى.  تكلمنا عن الـ ... الـ
+
+114
+00:09:03,100 --> 00:09:08,060
+terminologies related to the ... the body، في
+
+115
+00:09:08,060 --> 00:09:10,980
+عندنا ... في عندنا anterior side of the body، وفي
+
+116
+00:09:10,980 --> 00:09:14,240
+عندنا الـ posterior side of the body. لو ننظر من
+
+117
+00:09:14,240 --> 00:09:17,520
+الأمام فسنقول  الـ anterior. هذا الجزء كله يسمى
+
+118
+00:09:17,520 --> 00:09:22,280
+anterior. الـ back فهو posterior part. طبعاً anterior
+
+119
+00:09:22,280 --> 00:09:27,520
+تعني in front or toward the front. posterior to the
+
+120
+00:09:27,520 --> 00:09:34,840
+back، dorsal.  أما على جانب جسم الإنسان فالـ
+
+121
+00:09:34,840 --> 00:09:39,280
+ventral، الـ back نسميها dorsal، نسميها the dorsum
+
+122
+00:09:39,280 --> 00:09:42,580
+of the foot، هنا الـ ventral of the foot أو الـ
+
+123
+00:09:42,580 --> 00:09:46,780
+palmar surface of the hand، آسف، الـ ventral at the
+
+124
+00:09:46,780 --> 00:09:51,500
+belly side of the ... يعني ناحية البطن نسميه
+
+125
+00:09:51,500 --> 00:09:56,620
+ventral. ناحية الظهر نسميه dorsal. هو نفس الكلام
+
+126
+00:09:56,620 --> 00:10:01,620
+عن anterior والكلام عن posterior. يبقى anterior و
+
+127
+00:10:01,620 --> 00:10:06,280
+ventral كلمات مترادفة. posterior و dorsal كلمات
+
+128
+00:10:06,280 --> 00:10:11,120
+أيضاً مترادفة. لكن anterior عكسها posterior، و dorsal
+
+129
+00:10:11,120 --> 00:10:16,580
+عكسها ventral. أما عن الـ ...
+
+130
+00:10:19,600 --> 00:10:24,800
+الـ terminology الخاصة بالقرب من الرأس أو القرب من
+
+131
+00:10:24,800 --> 00:10:29,260
+الذيل أو من القدم. كل ما اقتربنا من الرأس فنحن
+
+132
+00:10:29,260 --> 00:10:34,360
+نكون superior، إلى أعلى، نرتفع إلى أعلى، means above
+
+133
+00:10:34,360 --> 00:10:40,060
+towards the head. أما الـ inferior،  نزولاً إلى أسفل، فهو رايح
+
+134
+00:10:40,060 --> 00:10:47,840
+towards the feet. caudal و cranial. الـ cranial هي دي
+
+135
+00:10:47,840 --> 00:10:50,840
+الـ skull،  اسمها cranial، في terminology، الـ skull
+
+136
+00:10:50,840 --> 00:10:55,340
+means cranial. طيب، كل ما اقتربنا إلى الـ cranial فهو
+
+137
+00:10:55,340 --> 00:10:59,220
+نسميه cranial. أما caudal نروح ناحية الذيل، تعرفون
+
+138
+00:10:59,220 --> 00:11:04,520
+أن حتى في الإنسان، في عظمة الذيل، التي هي العصعص،
+
+139
+00:11:04,520 --> 00:11:08,630
+نحن نسميها أو الـ coccyx. كل ما اقتربنا من هذه
+
+140
+00:11:08,630 --> 00:11:12,810
+المنطقة فنكون نحن caudal. أما لو طلعنا فوق، طبعاً،
+
+141
+00:11:12,810 --> 00:11:15,990
+terminology، نحتاج لمحاضرات كاملة في مجال
+
+142
+00:11:15,990 --> 00:11:20,570
+terminology، ستأخذونها إن شاء الله في الفصل القادم
+
+143
+00:11:20,570 --> 00:11:24,110
+أو إذا كنتم أخذتوها في الفصل الأول، فـ caudal نروح
+
+144
+00:11:24,110 --> 00:11:29,230
+ناحية الـ tail، الـ cranial نروح ناحية superior
+
+145
+00:11:29,230 --> 00:11:32,390
+medial
+
+146
+00:11:34,060 --> 00:11:41,850
+كل ما اقتربنا للمنتصف، فنحن نذهب إلى median، نذهب
+
+147
+00:11:41,850 --> 00:11:46,010
+lateral. يبقى الاقتراب من الـ midline means medial
+
+148
+00:11:46,010 --> 00:11:50,250
+الاقتراب من الـ ... البعد عن الـ midline means
+
+149
+00:11:50,250 --> 00:11:54,430
+lateral.  في حاجة اسمها deep and superficial. كل ما
+
+150
+00:11:54,430 --> 00:11:58,990
+صعدنا إلى السطح فنحن نكون superficial. كلما نزلنا
+
+151
+00:11:58,990 --> 00:12:04,010
+deep نكون نحن ... نكون deep، يعني نكون ...
+
+152
+00:12:04,010 --> 00:12:10,100
+نتحرك من الأعماق. طيب، هناك الكثير من الألفاظ هذه
+
+153
+00:12:10,100 --> 00:12:13,980
+تحتاج لأمثلة. لو تكلمنا، الـ skin هو superficial
+
+154
+00:12:13,980 --> 00:12:19,060
+لكن الـ muscle more deep، الـ bone أكثر عمقاً، لكن الـ
+
+155
+00:12:19,060 --> 00:12:23,060
+muscle superficial than الـ bone. الـ skin أكثر
+
+156
+00:12:23,060 --> 00:12:27,560
+superficial. فهذه الألفاظ نحن نستخدمها أحياناً
+
+157
+00:12:27,560 --> 00:12:31,580
+للمقارنة، يعني،  الذي يكون في اللحظة هذه، في بعض
+
+158
+00:12:31,580 --> 00:12:36,440
+المصطلحات، أو لما نصف بعض الأنسجة الموجودة في
+
+159
+00:12:36,440 --> 00:12:40,740
+الجسم، ممكن تكون في لحظة هي deep، ولحظة تكون
+
+160
+00:12:40,740 --> 00:12:43,920
+superficial. يعني تكون هي deep in relation to
+
+161
+00:12:43,920 --> 00:12:47,740
+other tissue، زي الـ bone، deep in relation to the
+
+162
+00:12:47,740 --> 00:12:50,760
+muscle. الـ muscle deeper than the skin، like skin
+
+163
+00:12:50,760 --> 00:12:55,060
+superficial. الـ muscle superficial than bone. وهدي
+
+164
+00:12:55,060 --> 00:12:58,500
+... هذا ما يلزمنا نحن لما نتعرف على هذه الـ
+
+165
+00:12:58,500 --> 00:13:03,140
+terminology.  وكما دائماً، نحن لو طلعنا على الـ upper
+
+166
+00:13:03,140 --> 00:13:07,220
+limb، فيها proximal وفيها distal، صحيح؟ طيب، إيش
+
+167
+00:13:07,220 --> 00:13:10,380
+يعني proximal، قريب من الـ trunk؟ إيش يعني distal
+
+168
+00:13:10,380 --> 00:13:14,160
+بعيدة عن الـ trunk؟ الـ hand is distal to the wrist،
+
+169
+00:13:14,640 --> 00:13:19,240
+distal to the elbow، distal to the shoulder، okay،
+
+170
+00:13:19,240 --> 00:13:20,660
+لكن الـ shoulder proximal
+
+171
+00:13:22,940 --> 00:13:26,460
+الـ elbow، لما أُقارنه بالـ shoulder، فهو distal to
+
+172
+00:13:26,460 --> 00:13:29,120
+the shoulder. لكن لو أُقارنه بالـ rest فهو
+
+173
+00:13:29,120 --> 00:13:31,040
+proximal to the shoulder
+
+174
+00:13:53,030 --> 00:13:59,350
+إن شاء الله، طبعاً في الـ anatomical terms، في كثير من
+
+175
+00:13:59,350 --> 00:14:05,270
+المصطلحات التي هي ممكن تكون كلمات يونانية أو لاتينية
+
+176
+00:14:05,270 --> 00:14:11,950
+أو يونانية.  فهذه لها مرادفات، لها مرادفات أين؟ في
+
+17
+
+223
+00:17:58,170 --> 00:18:03,060
+التارسل أما الـ helix فهو الـ big toes العضلات اللي
+
+224
+00:18:03,060 --> 00:18:06,300
+هناك بيسميها helices flexor helices extensor
+
+225
+00:18:06,300 --> 00:18:11,740
+helices فهي منطقة الـ big toe في الـ foot الـ
+
+226
+00:18:11,740 --> 00:18:16,280
+occipital الـ back أو الـ base of the skull بيسميها
+
+227
+00:18:16,280 --> 00:18:21,780
+occipital أو occipito-vertebral means spines، الـ
+
+228
+00:18:21,780 --> 00:18:26,160
+vertebra نفسها مكونات العمود الفقري بتكون من فقرات
+
+229
+00:18:26,160 --> 00:18:32,540
+متراسة فهو اسمها vertebral أو spinal scapular من
+
+230
+00:18:32,540 --> 00:18:37,080
+منطقة الـ shoulder blade، في هنا قدمة لسكابيولا
+
+231
+00:18:37,080 --> 00:18:43,200
+اللي هي لوحة الكتف اسمها scapula الـ Dorsum طيب و
+
+232
+00:18:43,200 --> 00:18:46,280
+اتعرفنا عليه قولنا الـ back الـ Dorsum of the hand و
+
+233
+00:18:46,280 --> 00:18:50,100
+الـ Dorsum of the foot اللي هي المنطقة العليا من
+
+234
+00:18:50,100 --> 00:18:52,160
+القدم
+
+235
+00:18:56,210 --> 00:19:00,830
+loin الـ sacral المنطقة الـ sacrum اللي هي موجودة
+
+236
+00:19:00,830 --> 00:19:04,910
+between the hips والبرنيال المنطقة اللي موجودة في
+
+237
+00:19:04,910 --> 00:19:09,810
+منطقة الـ genitalia و الـ femoral means thigh لأنه
+
+238
+00:19:09,810 --> 00:19:14,150
+في عضمة اسمها الـ femorous أو الـ femur فهي مسمية
+
+239
+00:19:14,150 --> 00:19:19,790
+femoral الكلكانية المنطقة عضمة الـ heel أو الكعب
+
+240
+00:19:19,790 --> 00:19:26,110
+plantar اللي هي السول plantar surface of the foot
+
+241
+00:19:26,110 --> 00:19:30,010
+plantar surface هنا بنسميه لكن الفوت بنسميه plantar
+
+242
+00:19:30,010 --> 00:19:33,470
+surface المنطقة اللي ملاسقة للأرض واحنا واقفين
+
+243
+00:19:33,470 --> 00:19:42,600
+فاسمها plantar الـ sole طبعا هذا توضيح كل الأشياء
+
+244
+00:19:42,600 --> 00:19:47,240
+اللي احنا اتكلمنا عنها قبل شوية بالرسم، مفيكم
+
+245
+00:19:47,240 --> 00:19:51,820
+تتبعوه سواء كان الـ forehead الـ frontal الـ orbital
+
+246
+00:19:51,820 --> 00:19:56,160
+منطقة الـ eye الـ pupil الشيك الـ mental chin الـ
+
+247
+00:19:56,160 --> 00:20:00,640
+nasal الـ oral cavity الـ cervical كل الـ
+
+248
+00:20:03,150 --> 00:20:06,730
+الـ terminology اللي احنا اتكلمنا عنها قبل شوية فهي
+
+249
+00:20:06,730 --> 00:20:11,590
+مفصلة على هذا الـ diagram نقدر نقول هذا الـ diagram
+
+250
+00:20:11,590 --> 00:20:19,230
+هو frontal view anterior view لأنه بيعطيني كل الجزء
+
+251
+00:20:19,230 --> 00:20:24,730
+الأمامي من الجسم مفصل طبعا كتير احنا لما بنيجي
+
+252
+00:20:24,730 --> 00:20:27,710
+نعمل الـ assessment أكرا نطلع على الشخص بنحتاج فيه
+
+253
+00:20:27,710 --> 00:20:30,730
+بعض الأشياء بنشوفها في الـ anterior view وفيه أشياء
+
+254
+00:20:30,730 --> 00:20:33,990
+ليه ممكن نستوضحها من الـ anterior view لازم نروح
+
+255
+00:20:33,990 --> 00:20:37,410
+للـ posterior وفي بعض الأشياء والحركات لازم نشوفها من
+
+256
+00:20:37,410 --> 00:20:42,080
+الـ lateral view وهذا كله إن شاء الله مع التقدم
+
+257
+00:20:42,080 --> 00:20:48,780
+خلّينا في المساقات هتتعرفوا عليه لاحقا، شايفين؟
+
+258
+00:20:48,780 --> 00:20:51,320
+اللي هتضطرين عشان نقول Occipital bone أو الـ
+
+259
+00:20:51,320 --> 00:20:56,580
+أوكسبتالبون لازم نطلع عليها من posterior view لازم
+
+260
+00:20:56,580 --> 00:21:01,180
+نطلع عليها من الخلف وهذه طبعا كل الأشياء اللي ممكن
+
+261
+00:21:01,180 --> 00:21:07,260
+نشوفها في جسم الإنسان من الـ posterior view زي الـ
+
+262
+00:21:07,260 --> 00:21:11,500
+occipital bone الـ crania من الـ posterior part
+
+263
+00:21:11,800 --> 00:21:15,800
+الـ Olecranon of the elbow، المنطقة الـ pupillary
+
+264
+00:21:15,800 --> 00:21:20,480
+part of the eye، هي الـ leg، الـ calcaneus، لازم
+
+265
+00:21:20,480 --> 00:21:23,400
+نشوفها من الأمام، لازم نشوفها من الأعلى، حتى
+
+266
+00:21:23,400 --> 00:21:27,120
+بتلاقوا أن الصور هذه كلها مروية بـ stereo view
+
+267
+00:21:27,120 --> 00:21:30,660
+و anterior view، عشان نعرف احنا من أنهي view، ممكن
+
+268
+00:21:30,660 --> 00:21:34,770
+نتطلع أو نشوف الأشياء هذه، الأشياء كتير مهمة حتى
+
+269
+00:21:34,770 --> 00:21:40,770
+احنا في خلال إن شاء الله اختبارنا للـ .. للمادة و
+
+270
+00:21:40,770 --> 00:21:44,870
+ماذا تحصلكم المادة هتكون كتير أسئلة في المجال هذا
+
+271
+00:21:44,870 --> 00:21:48,490
+حتى تكونوا عندكوا قدرة معرفة الأشياء أنتي لما
+
+272
+00:21:48,490 --> 00:21:51,110
+بنطلع عليها بنطلع عليها من which view من الـ
+
+273
+00:21:51,110 --> 00:21:55,800
+anterior ولا من الـ posterior طبعا لو قسمنا الـ body
+
+274
+00:21:55,800 --> 00:22:01,060
+احنا بنقسم الـ body لجزئين عندنا الـ axial portion و
+
+275
+00:22:01,060 --> 00:22:06,620
+عندنا الـ appendicular الـ axial هو الجسم عبارة عن
+
+276
+00:22:06,620 --> 00:22:13,090
+الـ head مع الـ neck, chest بيخلص من هنا بنسمي احنا
+
+277
+00:22:13,090 --> 00:22:17,790
+الـ trunk يبقى الـ head and neck and الـ trunk أما الـ
+
+278
+00:22:17,790 --> 00:22:22,110
+appendicular فـ means lower limb و الـ upper limb
+
+279
+00:22:22,110 --> 00:22:26,110
+يعني الـ arms و الـ legs يعني الإيدين والرجلين احنا
+
+280
+00:22:26,110 --> 00:22:29,980
+بالعربي بيقولها الـ upper limb كاملة و الـ lower
+
+281
+00:22:29,980 --> 00:22:34,660
+limb كاملة عشان كل واحد من هذه الأشياء المكونات
+
+282
+00:22:34,660 --> 00:22:38,080
+تبع جسم الإنسان اللي أعطتها هي أو المنظر لجسم
+
+283
+00:22:38,080 --> 00:22:43,320
+الإنسان كل واحد منهم ووظيفته الخاصة اللي خلق من
+
+284
+00:22:43,320 --> 00:22:47,080
+.. من أجلها طبعا في الـ axial portion في عنا
+
+285
+00:22:47,080 --> 00:22:51,820
+cavities هذه الـ cavities لازم احنا نتعرف عليها و
+
+286
+00:22:51,820 --> 00:22:56,400
+نكون عارفين ليها في عنا الـ cranial cavity لأن هذه
+
+287
+00:22:56,400 --> 00:23:00,740
+الـ جمجمة اللي بتحتوي على عضو مهم جدا من
+
+288
+00:23:00,740 --> 00:23:05,320
+أعضاء الجسم اللي هو الـ brain، الـ brain عشان هيك الـ
+
+289
+00:23:05,320 --> 00:23:08,800
+brain محطوط بالأضلاع، يعني وظيفة الأضلاع هنجي في مساق
+
+290
+00:23:08,800 --> 00:23:12,820
+.. لما نجي نوصل لـ الـ skeletal system إيش وظيفته؟
+
+291
+00:23:12,820 --> 00:23:20,310
+وظيفته إنه يحافظ على الأحشاء أو الحشوات اللي موجودة
+
+292
+00:23:20,310 --> 00:23:23,490
+فيه، يعني الـ cranium بتحافظ على الـ brain الـ
+
+293
+00:23:23,490 --> 00:23:27,090
+vertebral canal هذه اللي موجودة في الـ vertebral
+
+294
+00:23:27,090 --> 00:23:31,350
+column بتحافظ على الـ spinal cord أما هذه الأشياء
+
+295
+00:23:31,350 --> 00:23:34,630
+اللي بنشوفها احنا من الخلف أما من الأمام إيش بيكون
+
+296
+00:23:34,630 --> 00:23:37,250
+فيه؟ ثرس الـ cavity ثرس الـ cavity اللي بتطلع من
+
+297
+00:23:37,250 --> 00:23:40,530
+الأمام بتطلع أنا بتخيل لو شلنا العظم هذا وفتحته
+
+298
+00:23:40,530 --> 00:23:43,530
+بهذا الشكل إيش بيكون جوا؟ بيكون الـ lungs
+
+299
+00:23:43,530 --> 00:23:47,650
+الـ mediastinum الـ thymus الـ heart الـ oesophagus
+
+300
+00:23:47,650 --> 00:23:52,830
+الـ trachea كل هذه cavities موجودة في الـ
+
+301
+00:23:55,420 --> 00:23:59,420
+الـ cavity اللي موجودة بتاعة الـ chest cavity أما
+
+302
+00:23:59,420 --> 00:24:03,340
+الـ abdomino-pelvic فطبعا احنا بطلع على منطقة الـ
+
+303
+00:24:03,340 --> 00:24:06,500
+abdominal cavity بيكون فيه لنا الـ stomach و الـ
+
+304
+00:24:06,500 --> 00:24:09,960
+liver و spleen و جوا الـ greater الـ intestine سواء
+
+305
+00:24:09,960 --> 00:24:15,040
+large أو small intestine يعني كل اللي بنسميهم احنا
+
+306
+00:24:15,040 --> 00:24:20,980
+الأحشاء بالـ .. بالعربي، المعدة والكبد والطحال و
+
+307
+00:24:20,980 --> 00:24:25,780
+الأمعاء الغليظة والأمعاء الرفيعة والمرارة وكل
+
+308
+00:24:25,780 --> 00:24:30,080
+الأشياء هذه اللي بتكون موجودة، حتى الواحد لما بيتعمل
+
+309
+00:24:30,080 --> 00:24:34,100
+عملية، لما بيتعمل عملية في الأحشاء، بيروحوا بيفتحوا
+
+310
+00:24:34,100 --> 00:24:37,440
+بطنه، أما احتاج عملية في الرأس بيفتحوا الـ cranium
+
+311
+00:24:37,440 --> 00:24:40,220
+احتاج عملية مثلا في الـ spinal cord بيفتحوا الـ
+
+312
+00:24:40,220 --> 00:24:43,300
+spinal فحتى الـ position اللي بنوضع فيه المريض
+
+313
+00:24:43,300 --> 00:24:49,800
+هيختلف طبعا هيروح يفوت لـ الـ cranium من الخلف أو لـ
+
+314
+00:24:49,800 --> 00:24:53,240
+spinal cord بينام المريض على بطنه عشان يعرف يشتغل
+
+315
+00:24:53,240 --> 00:24:56,280
+أما هنا لو بنعمل abdominal surgery بينام المريض
+
+316
+00:24:56,280 --> 00:24:59,480
+على ظهره واحنا بنبقى عارفين حتى الـ positions هذه
+
+317
+00:24:59,480 --> 00:25:04,460
+كيف بدها تتعامل معها الأخصائيين أو الجراحين في هذا
+
+318
+00:25:04,460 --> 00:25:07,720
+لما بدهم يفوتوا لأنّهي cavity من هذه الـ cavities من
+
+319
+00:25:07,720 --> 00:25:12,600
+أيّ position هو بده يفوت منطقة الـ pelvic cavity اللي
+
+320
+00:25:12,600 --> 00:25:16,600
+هي منطقة الحوض بتحتوي على الـ urinary bladder
+
+321
+00:25:16,600 --> 00:25:21,720
+اللي هي المثانة وكل الـ internal reproductive organs
+
+322
+00:25:21,720 --> 00:25:26,640
+for male and female وطبعا هذا كله هنتكلم عليه في الـ
+
+323
+00:25:26,640 --> 00:25:31,620
+musculoskeletal system طبعا الـ diaphragm هي عبارة
+
+324
+00:25:31,620 --> 00:25:37,680
+عن عضلة بتقسم الـ cavities اللي موجودة جوا لـ upper
+
+325
+00:25:37,680 --> 00:25:42,240
+and lower دي فراغ هي عضلة التنفس الـ main
+
+326
+00:25:42,240 --> 00:25:47,520
+respiratory muscle اللي احنا لما بناخد inspiration
+
+327
+00:25:47,520 --> 00:25:51,280
+هي بصير فيها contraction بتوسع الـ thoracic cavity هذه
+
+328
+00:25:51,280 --> 00:25:55,200
+بتخلي الهوى يدخل، لكن هذه العضلة إيش وظيفتها؟ بتعمل
+
+329
+00:25:55,200 --> 00:25:58,380
+.. بتلعب دور أساسي في عملية التنفس وكمان بتلعب دور
+
+330
+00:25:58,380 --> 00:26:01,880
+أساسي بالفصل بين الـ cavities اللي موجودة في الجسم
+
+331
+00:26:01,880 --> 00:26:07,260
+الـ abdominal cavity و الـ thoracic cavity طبعا الـ
+
+332
+00:26:07,260 --> 00:26:10,540
+kidney و الـ adrenal gland و الـ pancreas و الـ
+
+333
+00:26:10,540 --> 00:26:15,640
+ureters are behind the abdomino-pelvic cavity هي
+
+334
+00:26:15,640 --> 00:26:24,340
+موجودة في البطن شوية لورا طبعا هذا رسم توضيحي لـ
+
+335
+00:26:24,340 --> 00:26:30,480
+الـ ventral cavity في أن هي الـ thoracic و الـ
+
+336
+00:26:30,480 --> 00:26:33,380
+diaphragm اللي هي العضلة هادي اللي بتقسم بين الـ
+
+337
+00:26:33,380 --> 00:26:37,660
+abdomen and chest وهاد الـ abdomen هاد الـ cavity و
+
+338
+00:26:37,660 --> 00:26:41,380
+هاد الـ pelvic cavity بتكون كتير lower في منطقة
+
+339
+00:26:41,380 --> 00:26:46,390
+الحوض فبسموها abdomino-pelvic cavity هنا من الـ
+
+340
+00:26:46,390 --> 00:26:49,050
+anterior view هنا اللي موجودة في الـ anterior side
+
+341
+00:26:49,050 --> 00:26:52,370
+بتيجي عندنا الحد والعلامة بتاعتنا للـ posterior في
+
+342
+00:26:52,370 --> 00:26:55,830
+عندنا الـ cranial cavity وفي عندنا الـ vertebral
+
+343
+00:26:55,830 --> 00:26:59,850
+cavity اللي هي بتحتوي على الـ spinal cord وفوق
+
+344
+00:26:59,850 --> 00:27:02,830
+بتحتوي على الـ brain
+
+345
+00:27:08,400 --> 00:27:12,540
+وها دراسة توضيحية أكثر برضه بيوضح لنا كل الأشياء
+
+346
+00:27:12,540 --> 00:27:16,140
+اللي احنا اتكلمنا عنها قبل شوية سواء اللي في
+
+347
+00:27:16,140 --> 00:27:20,740
+عندنا طبعا نتكلم على الـ chest cavity فيها بتحتوي
+
+348
+00:27:20,740 --> 00:27:26,680
+على الـ right و الـ left lungs الـ heart الـ mediastinum اللي
+
+349
+00:27:26,680 --> 00:27:31,580
+في عندنا الـ pleural cavity في عندنا الـ diaphragm
+
+350
+00:27:31,580 --> 00:27:35,880
+اللي هو شايفين بتفصل هذه المنطقة عن بتفصل الـ chest
+
+351
+00:27:35,880 --> 00:27:36,900
+عن الـ abdomen
+
+352
+00:27:44,820 --> 00:27:49,480
+هنروح على الـ membranes اللي موجودة جوا، طبعا هي الـ
+
+353
+00:27:49,480 --> 00:27:52,700
+membranes هي عبارة عن الأغشية اللي بتحيط في
+
+354
+00:27:52,700 --> 00:27:56,560
+الأنسجة، في عندنا نوعين من الـ membranes الـ
+
+355
+00:27:56,560 --> 00:28:00,020
+visceral وفي الـ parietal، الـ visceral هو اللي
+
+356
+00:28:00,020 --> 00:28:05,520
+بيحيط الأحشاء نفسها، أما الـ parietal فهي بتحيط الـ
+
+357
+00:28:05,520 --> 00:28:12,130
+body cavity نفسها طبعا الـ .. هدول الأنسجة ..
+
+358
+00:28:12,130 --> 00:28:15,810
+الأنسجة في عندنا طبقتين من الأنسجة وما بين هدول
+
+359
+00:28:15,810 --> 00:28:19,110
+الطبقتين في عندنا حاجة اسمها serous .. serous
+
+360
+00:28:19,110 --> 00:28:23,750
+fluid serous fluid هذا إيش وظيفته؟ وظيفته إنه يعمل
+
+361
+00:28:23,750 --> 00:28:29,910
+lubricant يمنع الاحتكاك يرتب الـ .. المكان حتى
+
+362
+00:28:29,910 --> 00:28:34,170
+يساعد على .. فاحنا إذا بناخد نفس بتتوسع الـ chest
+
+363
+00:28:34,170 --> 00:28:40,710
+صحيح؟ بتحاط الـ lungs في الـ pleural membrane بتكون
+
+364
+00:28:40,710 --> 00:28:44,430
+على أساس إنه ما بين الـ pleural و الـ parietal بيكون
+
+365
+00:28:44,430 --> 00:28:50,770
+في عندنا الـ serous fluid يبقى soft، thin
+
+366
+00:28:51,270 --> 00:28:56,110
+pliable layers of tissue that either يأما cover
+
+367
+00:28:56,110 --> 00:28:59,890
+الـ vital أو الـ visceral organs اللي هي موجودة في
+
+368
+00:28:59,890 --> 00:29:03,950
+الداخل اللي هي الحشوية أو الأحشاء، الـ parietal اللي
+
+369
+00:29:03,950 --> 00:29:08,430
+هي الجسدية اللي بتكون لبرا lines أو body cavity هي
+
+370
+00:29:08,430 --> 00:29:11,910
+الـ parietal membrane
+
+371
+00:29:13,420 --> 00:29:17,600
+طبعا هنا هيوضح لنا كل membrane من الموجودين سواء
+
+372
+00:29:17,600 --> 00:29:23,060
+في الـ lungs، سواء في الـ heart، سواء في الـ viscera،
+
+373
+00:29:23,060 --> 00:29:26,340
+إيش هو؟ there are specific names for membranes
+
+374
+00:29:26,340 --> 00:29:30,360
+around الـ heart و الـ lungs و الـ abdominal organs،
+
+375
+00:29:30,360 --> 00:29:34,800
+في عندنا الـ pleural membrane of the lungs كلنا سمعنا
+
+376
+00:29:34,800 --> 00:29:39,240
+يوما ما عن البلورة، في عندنا الـ visceral pleura
+
+377
+00:29:39,240 --> 00:29:44,640
+اللي محيط بالرئة نفسها فاسمها visceral pleura أما
+
+378
+00:29:44,640 --> 00:29:48,340
+الـ lines the cavity in which the lung is located يعني
+
+379
+00:29:48,340 --> 00:29:52,730
+عند الـ chest cage نفسه فاسمها parietal pleura in
+
+380
+00:29:52,730 --> 00:29:57,210
+between في عندنا هذا الـ fluid اللي في الـ serous
+
+381
+00:29:57,210 --> 00:30:01,530
+fluid أو الغشاء أو السائل المصلي اللي بيكون بيساعد
+
+382
+00:30:01,530 --> 00:30:06,970
+على الـ lubricant للمكان يعني احنا في عندنا pleura
+
+383
+00:30:06,970 --> 00:30:11,810
+هذه pleura الجزء المحيط بالـ lung اسمه visceral pleura
+
+384
+00:30:11,810 --> 00:30:17,870
+أما الجزء الملاسق لعظام الـ ribs وعظمة القفص فهى
+
+385
+00:30:17,870 --> 00:30:23,000
+اسمها parietal pleura الجزء الخارجي بيكون، يعني
+
+386
+00:30:23,000 --> 00:30:26,860
+الداخل اللي حوالين الأحشاء بيكون اسمه visceral أما
+
+387
+00:30:26,860 --> 00:30:31,040
+الخارج بيكون هو parietal، لكن احنا إنه بنشوفهم
+
+388
+00:30:31,040 --> 00:30:35,810
+كإنهم عندنا الرأس، نوضح  يورجينا إيه يعني؟ أما الـ
+
+389
+00:30:35,810 --> 00:30:40,310
+heart في عندنا visceral pericardium هو الملاصق that
+
+390
+00:30:40,310 --> 00:30:43,670
+membrane lines the cavity in which the heart is
+
+391
+00:30:43,670 --> 00:30:47,870
+located اسمه parietal، الـ visceral بيكون ملاصق للـ
+
+392
+00:30:47,870 --> 00:30:53,710
+heart أما الـ parietal فهو ملاصق للجزء أو المكان اللي
+
+393
+00:30:53,710 --> 00:31:00,090
+موجود فيه الـ heart وطبعا in between بيكون الـ serous
+
+394
+00:31:00,090 --> 00:31:06,070
+fluid هدول كتير مهم احنا نقرا، يبقى فيه عندنا
+
+395
+00:31:06,070 --> 00:31:08,850
+visceral pericardium وفيه عندنا parietal pericardium
+
+396
+00:31:08,850 --> 00:31:12,090
+و in between في عندنا حاجة اسمها
+
+397
+00:31:12,090 --> 00:31:16,050
+pericardial cavity، هذه موجودة بين الـ visceral و
+
+398
+00:31:16,0
+
+445
+00:34:53,210 --> 00:34:56,990
+فيها الأشياء اللي موجودة في الوسط زي ال
+
+446
+00:34:56,990 --> 00:35:00,630
+umbilical region منطقة الصرة احنا بنسميها هذه بتكون
+
+447
+00:35:00,630 --> 00:35:06,410
+في وسط الـ abdominal cavity هذه لحالها أخدت عملت
+
+448
+00:35:06,410 --> 00:35:13,320
+رقم فردي خلينا نسميها الـ other divisions أو
+
+449
+00:35:13,320 --> 00:35:18,040
+other regions زي الـ right hypochondriac region
+
+450
+00:35:18,040 --> 00:35:24,620
+منطقة تحت الـ ribs سموها right hypochondriac region
+
+451
+00:35:24,620 --> 00:35:27,780
+منطقة الـ lumber، الـ lumber احنا بنعرف منطقة الـ back
+
+452
+00:35:27,780 --> 00:35:30,260
+أو lower back، الـ lumber region أو المنطقة
+
+453
+00:35:30,260 --> 00:35:34,080
+القطنية هذه، ففي هذه المنطقة سموها الـ right lumbar
+
+454
+00:35:34,080 --> 00:35:37,580
+region، والـ right inguinal region المنطقة الأربية
+
+455
+00:35:37,580 --> 00:35:42,100
+اللي هي فيها كتير من الـ blood vessels و الـ
+
+456
+00:35:42,100 --> 00:35:47,020
+arteries و الـ veins و الـ lymph nodes و غيرها في
+
+457
+00:35:47,020 --> 00:35:53,490
+عندنا الـ epigastric منطقة أعلى المعدة اللي هي
+
+458
+00:35:53,490 --> 00:35:57,850
+واضحة عندنا بهذا الشكل هنا، هنا الـ umbilicus، الـ hypo
+
+459
+00:35:57,850 --> 00:36:05,210
+hypogastric تحت المعدة، والـ left  هلاقيتها بنرجع
+
+460
+00:36:05,210 --> 00:36:11,310
+مرة ثانية، الـ hypochondriac والـ  ... والـ lumber region والـ
+
+461
+00:36:11,310 --> 00:36:16,530
+... والـ ... والـ iliac region بس على الـ left side
+
+462
+00:36:16,530 --> 00:36:20,670
+عشان هيك صاروا فيه عندنا تسعة regions احنا بنتكلم
+
+463
+00:36:20,670 --> 00:36:28,440
+عنهم، وهذه الصورة بتوضح أكثر المناطق و وين وجودها هي
+
+464
+00:36:28,440 --> 00:36:32,700
+الـ epigastric حوالين المعدة، الـ umbilical حوالين اللي
+
+465
+00:36:32,700 --> 00:36:36,960
+هي السرّة، الـ pubic region منطقة اللي هي الحوض أو
+
+466
+00:36:36,960 --> 00:36:41,700
+أسفل البطن، الـ right groin منطقة الـ groin المنطقة
+
+467
+00:36:41,700 --> 00:36:46,620
+هذه اللي موجودة في الجسم، والـ hypochondriac الـ
+
+468
+00:36:46,620 --> 00:36:52,680
+right and left hypochondriac، إن شاء الله تكون هاي
+
+469
+00:36:52,680 --> 00:36:57,300
+آخر محاضرة، آخر slide  لعينها طبعاً، بشكركم إن شاء
+
+470
+00:36:57,300 --> 00:37:00,420
+الله على حسن استماعكم، وبتمنى إن هاي المحاضرات تكون
+
+471
+00:37:00,420 --> 00:37:04,320
+مفيدة لكم، وأي استفسار أنا نزلت على المجموعة الـ
+
+472
+00:37:04,320 --> 00:37:08,340
+WhatsApp إنّي أنا موجودة بكون يوم سبت واثنين في
+
+473
+00:37:08,340 --> 00:37:12,400
+الجامعة، أي حد بيحب يتواصل معايا أهلاً وسهلاً و
+
+474
+00:37:12,400 --> 00:37:13,200
+يعطيكم العافية
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..e635b758319fd5582e9a0de7edcf4f1ee372ca4f
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM_postprocess.srt
@@ -0,0 +1,1896 @@
+1
+00:00:05,010 --> 00:00:09,350
+بسم الله الرحمن الرحيم لمحاضرتنا اليوم التانية في
+
+2
+00:00:09,350 --> 00:00:15,290
+مساق ال anatomy المحاضرة السابقة اتعرفنا عليها
+
+3
+00:00:15,290 --> 00:00:18,530
+تعريف ال anatomy و ال physiology اليوم هتعرف على
+
+4
+00:00:18,530 --> 00:00:21,550
+بعض ال terminology اللي احنا عادة بنستخدمها في
+
+5
+00:00:21,550 --> 00:00:24,950
+مجال ال anatomy اللي بننجره منكوا طبعا كطلاب ان
+
+6
+00:00:24,950 --> 00:00:30,880
+شاء الله تكونوا حافظينها لآخر يومفي عمركوا اللي
+
+7
+00:00:30,880 --> 00:00:35,640
+بالتخصص بمعنى اللي بيشتغل في مجال المهن الصحية هذه
+
+8
+00:00:35,640 --> 00:00:39,640
+ال terminology لازم يكون حافظها للأبد و اللي طبعا
+
+9
+00:00:39,640 --> 00:00:43,280
+بيختار career تاني بعد ما يتخرج هو حر يحفظ أو ما
+
+10
+00:00:43,280 --> 00:00:47,490
+يحفظ هذا بيرجعلهال anatomical terminology هذه مهمة
+
+11
+00:00:47,490 --> 00:00:50,790
+لإنه هتنبني عليها كل المثقفات العملية و النظرية
+
+12
+00:00:50,790 --> 00:00:55,010
+اللي بدنا نفضها بعد هيك في مجال العلوم الصحية و
+
+13
+00:00:55,010 --> 00:00:58,710
+يفضل إنه احنا نكون حافظينها by heart لإن هي شغلات
+
+14
+00:00:58,710 --> 00:01:02,590
+صحيحة احنا اليوم هنكون عندنا دور في فهمهاوإدراكها
+
+15
+00:01:02,590 --> 00:01:07,410
+لكن هي بتنحفظ حفظ و هي عبارة عن كلمات متكررة في
+
+16
+00:01:07,410 --> 00:01:12,450
+سياق الدراسات ان شاء الله بالفصول القادمة كلها
+
+17
+00:01:12,450 --> 00:01:16,390
+بتسهل علينا عملية ال .. لنقول متابعة الدراسة بتسهل
+
+18
+00:01:16,390 --> 00:01:21,410
+علينا عملية القراءة و الاطلاع و الفهموإدراك حتى ما
+
+19
+00:01:21,410 --> 00:01:26,250
+نقيدش كل مرة نفسر المصطلحات هذه اسمها مصطلحات لازم
+
+20
+00:01:26,250 --> 00:01:29,950
+احنا نعرفها وأعتقد ان في منكم أخد مساقى المصطلحات
+
+21
+00:01:29,950 --> 00:01:34,050
+الطبية قد يكون مر عليه جزء منها الا ان في مجال
+
+22
+00:01:34,050 --> 00:01:37,930
+مساقى ال anatomy ما بنقدر الا ان احنا ناخدها ال
+
+23
+00:01:37,930 --> 00:01:40,350
+anatomical terminology اللى احنا نتحرف عليها أهم
+
+24
+00:01:40,350 --> 00:01:43,530
+اشي انه ان ال anatomical position هو اذا كان ان
+
+25
+00:01:43,530 --> 00:01:46,170
+شاء الله الكاميرا بتكشفني هو هذا الوضع انه بيوقف
+
+26
+00:01:46,170 --> 00:01:51,470
+الشخصبهذا الشكل ال face forward ال hands ال
+
+27
+00:01:51,470 --> 00:01:55,810
+balance forward و ال thumb لبرا و الأجرتين apart
+
+28
+00:01:55,810 --> 00:01:59,630
+طبعا واضحة بالصورة أن هذا اسمه anatomical position
+
+29
+00:01:59,630 --> 00:02:04,710
+يعني أي هو ال reference لكلمصطلح احنا بنتكلم بعدي
+
+30
+00:02:04,710 --> 00:02:09,270
+.. بنتكلم عنه في مجالاتنا المختلفة هو ال .. ال ..
+
+31
+00:02:09,270 --> 00:02:13,510
+ال .. ال position ال reference يعني لما بنتكلم عن
+
+32
+00:02:13,510 --> 00:02:17,410
+reflection انا بتكلم عن reflection من extended arm
+
+33
+00:02:17,410 --> 00:02:20,130
+بهذا الشكل نتكلم من supination و antipronation
+
+34
+00:02:20,130 --> 00:02:24,310
+نتكلم من هذا و كل المصالحات هذه هنمر عليها خلال
+
+35
+00:02:24,310 --> 00:02:28,450
+محاضرتنا طيب يعني هي عبارة عن إيش؟ هو position
+
+36
+00:02:30,190 --> 00:02:35,810
+الشخص بيكون فيه واقف upright ال feet على الأرض و
+
+37
+00:02:35,810 --> 00:02:39,390
+parallel و flat على ال floor زي ما احنا شايفين
+
+38
+00:02:39,390 --> 00:02:46,030
+بالمنظر اللي قدامنا هذا ال hip بيكون على مستوى ال
+
+39
+00:02:46,030 --> 00:02:51,770
+eyes بتطلع لقدام بتطلع الشخص فيه forwardطبعا كإنه
+
+40
+00:02:51,770 --> 00:02:55,990
+في حد واقف قدامك و بيتطلع عليه دايما بيكون to the
+
+41
+00:02:55,990 --> 00:03:00,370
+side الارض زى ما احنا شايفين ال side of the body و
+
+42
+00:03:00,370 --> 00:03:04,210
+بالطبع الفرنس forward و ال thumb ال lateral
+
+43
+00:03:04,210 --> 00:03:09,770
+positionطبعا في حاجة اسمها plans، إيش ال plans؟ هي
+
+44
+00:03:09,770 --> 00:03:16,310
+عبارة عن مقاطع للجسم بتسهل عملية تقسيم الجسم و
+
+45
+00:03:16,310 --> 00:03:20,010
+الحركة، لإن الحركة بتحصل في planet، في plan يعني
+
+46
+00:03:20,010 --> 00:03:24,460
+في عندنا imaginary surfaceمش بيعمل بيعمل cutting ل
+
+47
+00:03:24,460 --> 00:03:28,840
+ال body من خلال هذا ال cut اللي بيعمله بيخلينا
+
+48
+00:03:28,840 --> 00:03:32,240
+نقدر نفسر مثلا حركة ال flexion و ال extension
+
+49
+00:03:32,240 --> 00:03:35,700
+بيصير putsch plan مدان فى أننا plan و فى أننا حركة
+
+50
+00:03:35,700 --> 00:03:40,180
+يبقى فى أننا access ل الحركة plan is an imaginary
+
+51
+00:03:40,180 --> 00:03:46,710
+surface thatslices the body into specific sections
+
+52
+00:03:46,710 --> 00:03:51,970
+بيسموه لمقاطع سواء مقاطع طولية أو مقاطع عرضية طيب
+
+53
+00:03:51,970 --> 00:03:54,830
+إيش ال measure plans اللي إحنا بنتكلم عنهم؟ في
+
+54
+00:03:54,830 --> 00:03:57,670
+عندنا تلاتة measure هي ال coronary و ال transverse
+
+55
+00:03:57,670 --> 00:04:01,310
+و ال sagittal ال plan اللي كل الحركة اللي إحنا
+
+56
+00:04:01,310 --> 00:04:07,190
+بنتحركها بتدور في هدولة ال plans أو هذه الأسطح
+
+57
+00:04:07,190 --> 00:04:11,070
+اللي خليني نقول عنها التخيلية
+
+58
+00:04:13,190 --> 00:04:19,290
+طيب ال coronary plan هو عبارة عن plan بيقسم الجسم
+
+59
+00:04:19,290 --> 00:04:25,150
+بمقطع بهذا الشكلانقسام الجسم بهذا الشكل يعني في
+
+60
+00:04:25,150 --> 00:04:29,810
+عندنا anterior و في عندنا posterior surface يعني
+
+61
+00:04:29,810 --> 00:04:34,570
+في عندنا أمام و في عندنا خلال لأن ننظر للشخص هو
+
+62
+00:04:34,570 --> 00:04:39,350
+قدامنا نطلع عليه من قدام على ال anterior plan فهو
+
+63
+00:04:39,350 --> 00:04:43,310
+بيكون نظر عليه بال frontal plan و لو دهره فاحنا
+
+64
+00:04:43,310 --> 00:04:48,260
+بنتكلم عن ال back فهو ال posterior planأى مقطع فى
+
+65
+00:04:48,260 --> 00:04:52,900
+الجسم بهذا الشكل بهذا الشكل بيكون بيقطعوا نسميه فى
+
+66
+00:04:52,900 --> 00:04:58,820
+ال corner أو ال frontal قبلة أما ال transverse وهو
+
+67
+00:04:58,820 --> 00:05:05,560
+المقطع ال horizontal بيقطعوا نصين يا إما هو نصين
+
+68
+00:05:05,560 --> 00:05:09,600
+على الأكيد دائما لازم نص تحت و نص فوق بس بياخدوا
+
+69
+00:05:09,600 --> 00:05:16,370
+من مقاطع مختلفة طبعاإحنا لما بنقطع الجسم بهذا
+
+70
+00:05:16,370 --> 00:05:20,030
+الشكل معناه الحركات اللي بتصير حركات تقريبا بتكون
+
+71
+00:05:20,030 --> 00:05:23,230
+بهذا الشكل اللي هي الحركات الدورانية بهذا الشكل
+
+72
+00:05:23,230 --> 00:05:26,830
+أنا لما بشتغل بهذا الشكل أنا بشتغل ملامسة لإيش
+
+73
+00:05:26,830 --> 00:05:33,090
+ملامسة لل horizontal plan طبعا كل plan الحركة
+
+74
+00:05:33,090 --> 00:05:35,090
+بتصير فيه عن طريق axis
+
+75
+00:05:40,450 --> 00:05:44,970
+لما بنتكلم هيك انا لما بتكلم حركة بهذا الشكل بهذا
+
+76
+00:05:44,970 --> 00:05:47,670
+الشكل انا الحركة اللي قاعدة في ال horizon is plan
+
+77
+00:05:47,670 --> 00:05:52,190
+لازم يكون في عندي longitudinal axis بهذا الشكل هيك
+
+78
+00:05:52,190 --> 00:06:03,230
+و هيك ففي عندي axis بيمر في طول على طول الجسم انا
+
+79
+00:06:03,230 --> 00:06:09,900
+سجطة ال plan فهو بيقسم الجسم لجزئينطولي right and
+
+80
+00:06:09,900 --> 00:06:14,440
+left لو كان ماشي في مص الجسم فهو بيقسم الجسم
+
+81
+00:06:14,440 --> 00:06:17,220
+لجزئين متشابهين as a mirror
+
+82
+00:06:37,720 --> 00:06:41,480
+يكون يبقى في عندنا right side و في عندنا left side
+
+83
+00:06:41,480 --> 00:06:48,140
+نسميه median ابلان لما بيقسم الجسم لجزئين متساويين
+
+84
+00:06:48,140 --> 00:06:53,700
+left and right طبعا ممكن يصير في عندنا sections
+
+85
+00:06:53,700 --> 00:06:57,240
+يعني مش شرط انه يقسم الجسم من المنتصف ممكن يقسمه
+
+86
+00:06:57,240 --> 00:07:01,260
+من هنا من هنا من هنا من هنا ياخد مقاطع مختلفة لما
+
+87
+00:07:01,260 --> 00:07:05,400
+يكون في النصف فهو بيكون ال mid-sagittal ابلان
+
+88
+00:07:08,290 --> 00:07:13,010
+قطعوا لأجزاء مش ملاصفة فبنسمي ال بارا sagittal
+
+89
+00:07:13,010 --> 00:07:16,030
+يعني المهم أن في عندنا left side و في عندنا right
+
+90
+00:07:16,030 --> 00:07:21,430
+side ماكنتش بيكون oblique لما بيكون مش vertical ال
+
+91
+00:07:21,430 --> 00:07:25,870
+axis فبتصير في عندنا كانوا عامل an angle بنسمي
+
+92
+00:07:25,870 --> 00:07:32,730
+oblique plan هنا
+
+93
+00:07:32,730 --> 00:07:38,970
+طبعا احنا عرفنا ال two plansانا بتمنى منكوا كل
+
+94
+00:07:38,970 --> 00:07:45,720
+واحد يحاوليعمل الحركات و يقسم الحركات هذه اللى فى
+
+95
+00:07:45,720 --> 00:07:49,740
+الجسم على ال plans اللى موجودة هنتكلم عن ال
+
+96
+00:07:49,740 --> 00:07:52,460
+movement لما نتكلم عن ال musculoskeletal system بس
+
+97
+00:07:52,460 --> 00:07:56,220
+بدنا نذكر الكلام الكلام عن ال plan و ال accesses
+
+98
+00:07:56,220 --> 00:07:59,540
+عشان يوم ما بنحكي عن ال movement بدنا نرجعلها
+
+99
+00:07:59,540 --> 00:08:04,260
+نرجعلها بالتفصيل على أساس أنه نعرف كل حركة مثلا
+
+100
+00:08:04,260 --> 00:08:07,260
+حركة reflection of the elbow reflection and
+
+101
+00:08:07,260 --> 00:08:13,730
+extension بتكون فى which plan بتكون هيقاطع فبتكون
+
+102
+00:08:13,730 --> 00:08:16,750
+الحركة في ال digital plan لكن ال axis سبقها بيكون
+
+103
+00:08:16,750 --> 00:08:22,050
+بهذا الشكل في ال frontal plan ال axis هذا بده شرح
+
+104
+00:08:22,050 --> 00:08:25,850
+تفاصيل ان شاء الله هشرحه في وقته لما نوصل ل
+
+105
+00:08:25,850 --> 00:08:29,430
+movements of the body في ال musculoskeletal system
+
+106
+00:08:30,080 --> 00:08:33,580
+أما ال directional terms فإحنا لازم نعرف إيش تعني
+
+107
+00:08:33,580 --> 00:08:36,680
+كلمة superior، إيش تعني كلمة inferior، إيش تعني
+
+108
+00:08:36,680 --> 00:08:40,360
+كلمة lateral، إيش تعني كلمة medial، abduction،
+
+109
+00:08:40,360 --> 00:08:44,260
+adduction، كل الألفاظ هذه لنتعرف عليها من خلال
+
+110
+00:08:44,260 --> 00:08:48,840
+المصطلحات القادمة
+
+111
+00:08:48,840 --> 00:08:52,560
+المصطلحات دايما في عندنا opposition، دايما في
+
+112
+00:08:52,560 --> 00:08:56,760
+عندنا right، left، superior، inferior، abduction،
+
+113
+00:08:56,760 --> 00:09:03,100
+adduction، هنشوفهالو اتكلمنا عن ال .. ال
+
+114
+00:09:03,100 --> 00:09:08,060
+terminologies ال related to the .. the body فى
+
+115
+00:09:08,060 --> 00:09:10,980
+عندنا .. فى عندنا anterior side of the body و فى
+
+116
+00:09:10,980 --> 00:09:14,240
+عندنا ال posterior side of the body لو نطلع من
+
+117
+00:09:14,240 --> 00:09:17,520
+قدام فاحنا بنتكلم عن ال anterior كل هذا الجزء اسمه
+
+118
+00:09:17,520 --> 00:09:22,280
+anterior ال back فهو posterior part طبعا anterior
+
+119
+00:09:22,280 --> 00:09:27,520
+تعني in front or toward the front posterior to the
+
+120
+00:09:27,520 --> 00:09:34,840
+backالدورسل at the side of the human body اما ال
+
+121
+00:09:34,840 --> 00:09:39,280
+ventral ال back اسمها دورسل ها بنسميها the dorsum
+
+122
+00:09:39,280 --> 00:09:42,580
+of the foot هنا ال ventral of the foot او ال
+
+123
+00:09:42,580 --> 00:09:46,780
+palmar surface of the hand sorry ال ventral at the
+
+124
+00:09:46,780 --> 00:09:51,500
+bellyside of the .. يعني ناحية البطل بنسميه
+
+125
+00:09:51,500 --> 00:09:56,620
+ventral ناحية الدهر بنسميه dorsal هو نفسه الكلام
+
+126
+00:09:56,620 --> 00:10:01,620
+عن anterior و الكلام عن posterior يبقى anterior و
+
+127
+00:10:01,620 --> 00:10:06,280
+ventral كلمات مترادفة posterior و dorsal كلمات
+
+128
+00:10:06,280 --> 00:10:11,120
+أيضا مترادفة لكن anterior عكسها posterior و dorsal
+
+129
+00:10:11,120 --> 00:10:16,580
+عكسها ventral أما عن ال ..
+
+130
+00:10:19,600 --> 00:10:24,800
+الـ Terminology الخاصة بالقرب من الرأس أو القرب من
+
+131
+00:10:24,800 --> 00:10:29,260
+الذيل أو من الفوتو كل ما اقتربنا من الرأس فاحنا
+
+132
+00:10:29,260 --> 00:10:34,360
+بنكون superior إلى أعلى طلع إلى أعلى means above
+
+133
+00:10:34,360 --> 00:10:40,060
+towards the head أما ال inferior مازل تحت فهو رايح
+
+134
+00:10:40,060 --> 00:10:47,840
+towards the feetcodal و cranial ال cranial هي دي
+
+135
+00:10:47,840 --> 00:10:50,840
+ال skull اسمها cranial في terminology ال skull
+
+136
+00:10:50,840 --> 00:10:55,340
+means cranial طب كل ما اقتربنا إلى ال cranial فهو
+
+137
+00:10:55,340 --> 00:10:59,220
+بنسميه cranial أما codal بنروح ناحية الذيل بتعرفوا
+
+138
+00:10:59,220 --> 00:11:04,520
+أنه حتى في الإنسان في عظمة الذيل اللي هي الأصوص
+
+139
+00:11:04,520 --> 00:11:08,630
+احنا بنسميها أو ال coaxes كل ما اقتربنا منهذه
+
+140
+00:11:08,630 --> 00:11:12,810
+المنطقة فبنكون احنا codal اما لو طلعنا فوق طبعا
+
+141
+00:11:12,810 --> 00:11:15,990
+terminology نحتاج لمحادرات كاملة في مجال
+
+142
+00:11:15,990 --> 00:11:20,570
+terminology هتاخدوها ان شاء الله في الفصل القادم
+
+143
+00:11:20,570 --> 00:11:24,110
+او اذا كنتوا اخدوها في الفصل الاول فcodal بنروح
+
+144
+00:11:24,110 --> 00:11:29,230
+ناحيت ال tail ال cranial بنروح أضاف superior
+
+145
+00:11:29,230 --> 00:11:32,390
+medial
+
+146
+00:11:34,060 --> 00:11:41,850
+كل ما اقتربنا للمنتصف فاحنا بنروح medianبنروح
+
+147
+00:11:41,850 --> 00:11:46,010
+lateral يبقى الاقتراب من ال midline means medial
+
+148
+00:11:46,010 --> 00:11:50,250
+الاقتراب من ال .. البتعاد عن ال midline means
+
+149
+00:11:50,250 --> 00:11:54,430
+lateral في حاجة اسمها deep and superficial كل ما
+
+150
+00:11:54,430 --> 00:11:58,990
+طلعنا على السطح فاحنا بنكون superficial كنا نزلنا
+
+151
+00:11:58,990 --> 00:12:04,010
+deep بنكون احنا .. بنكون deep يعني بنكون ..
+
+152
+00:12:04,010 --> 00:12:10,100
+بنتنقلب من الأعماق طيب هنابكتير من الألفاظ هذه
+
+153
+00:12:10,100 --> 00:12:13,980
+بتحتاج لأمثلة لو اتكلمنا ال skin هو superficial
+
+154
+00:12:13,980 --> 00:12:19,060
+لكن ال muscle more deep ال bone deep أكتر لكن ال
+
+155
+00:12:19,060 --> 00:12:23,060
+muscle superficial than ال bone ال skin أكتر
+
+156
+00:12:23,060 --> 00:12:27,560
+superficial فهذه الألفاظ احنا بنستخدمها أحيانا
+
+157
+00:12:27,560 --> 00:12:31,580
+للمقارنة يعني اللي بيكون في اللحظة هذهفي بعض
+
+158
+00:12:31,580 --> 00:12:36,440
+المصطلحات أو لما بنوصف بعض الأنسجة اللي موجودة في
+
+159
+00:12:36,440 --> 00:12:40,740
+الجسم ممكن تكون في لحظة هي deep و لحظة تكون
+
+160
+00:12:40,740 --> 00:12:43,920
+superficial يعني بتكون هي deep in relation to
+
+161
+00:12:43,920 --> 00:12:47,740
+other tissue زي ال bone، deep in relation to the
+
+162
+00:12:47,740 --> 00:12:50,760
+muscle ال muscle deeper than the skin like skin
+
+163
+00:12:50,760 --> 00:12:55,060
+superficial ال muscle superficial than bone وهدي
+
+164
+00:12:55,060 --> 00:12:58,500
+.. هذا اللي بيلزمنا احنا لما نتعرف على هذه ال
+
+165
+00:12:58,500 --> 00:13:03,140
+terminologyوكمان دائما احنا لو طلعنا على ال upper
+
+166
+00:13:03,140 --> 00:13:07,220
+limb، فيها proximal و فيها distal، صحيح؟ طيب، إيش
+
+167
+00:13:07,220 --> 00:13:10,380
+يعني proximal قريب من ال trunk؟ إيش يعني distal
+
+168
+00:13:10,380 --> 00:13:14,160
+بعيدة عن ال trunk؟ ال hand is distal to the wrist,
+
+169
+00:13:14,640 --> 00:13:19,240
+distal to the elbow, distal to the shoulder، okay،
+
+170
+00:13:19,240 --> 00:13:20,660
+لكن ال shoulder proximal
+
+171
+00:13:22,940 --> 00:13:26,460
+الإلبو لما بدي أقارنه بال shoulder فهو distal to
+
+172
+00:13:26,460 --> 00:13:29,120
+the shoulder لكن لو بدي أقارنه بال rest فهو
+
+173
+00:13:29,120 --> 00:13:31,040
+proximal to the shoulder
+
+174
+00:13:53,030 --> 00:13:59,350
+ان شاء الله طبعا في ال anatomical terms في كتير من
+
+175
+00:13:59,350 --> 00:14:05,270
+المصطلحات اللي هي ممكن تكون كلمات غرقية او لاتينية
+
+176
+00:14:05,270 --> 00:14:11,950
+او يونانية فهذه الها مرادفات الها مرادفات وين؟ في
+
+177
+00:14:11,950 --> 00:14:18,330
+اللغة الإنقليزية فلو كنا ال cephalic means head ال
+
+178
+00:14:18,330 --> 00:14:24,750
+frontal بتسوي ال fourhead نيزل يعني nose ال orbit
+
+179
+00:14:24,750 --> 00:14:31,130
+كلمة كتير مختلفة means eyes orbital يبقى إشي
+
+180
+00:14:31,130 --> 00:14:36,550
+حوالين ال eyes نيزل فإشي حوالين ال nose
+
+181
+00:14:43,220 --> 00:14:49,280
+Poxal cheek مثلا العضلات اسمها Poxy عادة فاسمها
+
+182
+00:14:49,280 --> 00:14:54,140
+Poxal ال oral منطقة ال mouth ال mouth means oral
+
+183
+00:14:54,140 --> 00:14:57,760
+لما اتكلم عن oral oral cavity يبقى منطقة ال cavity
+
+184
+00:14:57,760 --> 00:15:04,120
+اللي موجودة في ال mouth cervical neck اتكلم عن اي
+
+185
+00:15:04,120 --> 00:15:07,400
+اشي cervical بين cervical, spondylosis, cervical
+
+186
+00:15:07,400 --> 00:15:12,800
+whatever احنا اللي بنتكلم عنه فهو means neckmental
+
+187
+00:15:12,800 --> 00:15:18,240
+chin دقن acromial هنا ال shoulder ليش لأن في عضلة
+
+188
+00:15:18,240 --> 00:15:22,240
+هنتعرف علي اسمها ال acromion هنا في رأس الكتف فهو
+
+189
+00:15:22,240 --> 00:15:26,820
+عشان يكي بيرمزله ال shoulder بال acromial sternal
+
+190
+00:15:26,820 --> 00:15:30,840
+منطقة ال breast bone اللي هي ال sternum عظمة اللي
+
+191
+00:15:30,840 --> 00:15:36,100
+بنسميها القص اكسل لرئيه ال armpit اللي هو احنا
+
+192
+00:15:36,100 --> 00:15:41,670
+بنسميه ال ابتexellar crutches لما بيمسك الشخص على
+
+193
+00:15:41,670 --> 00:15:46,270
+الككيز اللي تحت القبد بيسميه exellar لرمزها يعني
+
+194
+00:15:46,270 --> 00:15:51,890
+بنوصفها بهذا الشكل thoracic means schist منطقة ال
+
+195
+00:15:51,890 --> 00:15:56,370
+thorax كلها هي منطقات ال schist mammary ماماري
+
+196
+00:15:56,370 --> 00:16:01,990
+اللي هي ال breasts brachial في هنا عضمة اسمها
+
+197
+00:16:01,990 --> 00:16:05,590
+brachial bone فعشان هي بتسمى منطقة القارب هذه
+
+198
+00:16:05,590 --> 00:16:07,190
+اسمها brachial
+
+199
+00:16:11,580 --> 00:16:15,940
+Anticubital منطقة إيش؟ ال forward part أو ال
+
+200
+00:16:15,940 --> 00:16:22,360
+anterior part of the elbow الolecranon،
+
+201
+00:16:22,360 --> 00:16:25,320
+في عضمة هنا اسمها olecranon، فبنسميها olecranon،
+
+202
+00:16:25,320 --> 00:16:30,140
+هي منطقة راس ال elbow joint أو ال back of the
+
+203
+00:16:30,140 --> 00:16:35,330
+elbow jointالـ Antibracial اللي هي الـ forearm،
+
+204
+00:16:35,330 --> 00:16:42,130
+هذه العضمة اسمها forearm، Popliteal هي posterior
+
+205
+00:16:42,130 --> 00:16:46,110
+of the knee، منطقة الـ back of the knee فهي اسمها
+
+206
+00:16:46,110 --> 00:16:50,730
+الـ Popliteal area، هنشوف فائدها على ال diagrams
+
+207
+00:16:51,910 --> 00:16:56,130
+sural ال calf في عضمة اسمها عضلة اسمها ال calf
+
+208
+00:16:56,130 --> 00:17:00,410
+muscle، carpel منطقة ال wrists يعني بيسميها carpel
+
+209
+00:17:00,410 --> 00:17:03,210
+لإن في عندنا تمانية carpel bones اتعرف عليهم في
+
+210
+00:17:03,210 --> 00:17:07,390
+الانهاتف من بكرا و نحفظهم اسمها carpel bones فهي
+
+211
+00:17:07,390 --> 00:17:11,870
+منطقة المنطقةالـ Pollocks بيسميه Pollicis اللي هو
+
+212
+00:17:11,870 --> 00:17:15,530
+منطقة الثمب، كل العضلات اللي في منطقة الثمب، الثمب
+
+213
+00:17:15,530 --> 00:17:19,810
+بيسميها Pollicis ال digital هي ال fingers عبارة عن
+
+214
+00:17:19,810 --> 00:17:24,170
+الأصابع، أصابع الأديان أو أصابع الرجلين ال pubic
+
+215
+00:17:24,170 --> 00:17:29,250
+منطقة الجينيتاليا، منطقة الأعضاء التناثلية فبتسمى
+
+216
+00:17:29,250 --> 00:17:32,310
+pubic، نتيجة ل .. ليش اتسمت هيك؟ لإن في عضمة في
+
+217
+00:17:32,310 --> 00:17:37,110
+هذا المكان اسمها pupisالباتلر في الصابونة الرجل
+
+218
+00:17:37,110 --> 00:17:40,290
+اسمها باتلر فأي شي related لهذا المنطقة بتسمي
+
+219
+00:17:40,290 --> 00:17:44,230
+باتلر اللي هي anterior part of the knee Plural
+
+220
+00:17:44,230 --> 00:17:49,090
+منطقة ال leg تارسل منطقة ال ankles لإن في انا
+
+221
+00:17:49,090 --> 00:17:53,770
+تارسل bones تارسل وميتا تارسل التارسل bone اللي هي
+
+222
+00:17:53,770 --> 00:17:58,170
+عضمة ال .. عضمة ال heel التالس والكلكانيا بتسمى
+
+223
+00:17:58,170 --> 00:18:03,060
+التارسلأما ال helix فهو ال big toes العضلات اللي
+
+224
+00:18:03,060 --> 00:18:06,300
+هناك بيسميها helices flexor helices extensor
+
+225
+00:18:06,300 --> 00:18:11,740
+helices فهي منطقة ال big two في ال food ال
+
+226
+00:18:11,740 --> 00:18:16,280
+occipital ال back أو ال base of the skull بيسميها
+
+227
+00:18:16,280 --> 00:18:21,780
+occipital أو occipotال vertebral means spines، ال
+
+228
+00:18:21,780 --> 00:18:26,160
+vertebra نفسها مكونات العمود الفقري بتكون من فقرات
+
+229
+00:18:26,160 --> 00:18:32,540
+متراسة فهو اسمها vertebral أو spinal scapular من
+
+230
+00:18:32,540 --> 00:18:37,080
+منطقة ال shoulder blade، في هنا قدمة لسكابيولا
+
+231
+00:18:37,080 --> 00:18:43,200
+اللي هي لوحة الكتف اسمها scapulaالـ Dorsum طيب و
+
+232
+00:18:43,200 --> 00:18:46,280
+اتعرفنا عليه قولنا ال pack ال Dorsum of the hand و
+
+233
+00:18:46,280 --> 00:18:50,100
+ال Dorsum of the foot اللي هي المنطقة العليا من
+
+234
+00:18:50,100 --> 00:18:52,160
+القدم
+
+235
+00:18:56,210 --> 00:19:00,830
+loin الـ sacral المنطقة الـ sacrum اللي هي موجودة
+
+236
+00:19:00,830 --> 00:19:04,910
+between the hips والبرنيال المنطقة اللي موجودة في
+
+237
+00:19:04,910 --> 00:19:09,810
+منطقة ال genitalia و ال femoral means thigh لأنه
+
+238
+00:19:09,810 --> 00:19:14,150
+في عضمة اسمها ال femorous او ال femur فهي مسمية
+
+239
+00:19:14,150 --> 00:19:19,790
+femoral الكلكانية المنطقة عضمة ال ال heel او الكعب
+
+240
+00:19:19,790 --> 00:19:26,110
+plantar اللي هي السولplantar surface of the heart
+
+241
+00:19:26,110 --> 00:19:30,010
+بعلمر surface هنا بنسميه لكن الفوت بنسميه plantar
+
+242
+00:19:30,010 --> 00:19:33,470
+surface المنطقة اللي ملاسقة للأرض و احنا واقفين
+
+243
+00:19:33,470 --> 00:19:42,600
+فاسمها plantar ال soul طبعا هذاتوضيح كل الأشياء
+
+244
+00:19:42,600 --> 00:19:47,240
+اللى احنا اتكلمنا عنها قبل شوية بالرسم مفيكم
+
+245
+00:19:47,240 --> 00:19:51,820
+تتبعوه سواء كان ال forehead ال frontal ال orbital
+
+246
+00:19:51,820 --> 00:19:56,160
+منطقة ال eye ال pixel الشيك ال mental chin ال
+
+247
+00:19:56,160 --> 00:20:00,640
+nasal ال oral cavity ال cervical كل ال
+
+248
+00:20:03,150 --> 00:20:06,730
+ال terminology اللي احنا اتكلمنا عنها قبل شوية فهي
+
+249
+00:20:06,730 --> 00:20:11,590
+مفصلة على هذا ال diagram نقدر نقول هذا ال diagram
+
+250
+00:20:11,590 --> 00:20:19,230
+هو frontalview anterior view لأنه بيعطيني كل الجزء
+
+251
+00:20:19,230 --> 00:20:24,730
+الأمامي من الجسم مفصل طبعا كتير احنا لما بنيجي
+
+252
+00:20:24,730 --> 00:20:27,710
+نعمل ال assessment أكرا نطلع على الشخص بنحتاج فيه
+
+253
+00:20:27,710 --> 00:20:30,730
+بعض الأشياء بنشوفها في ال anterior view وفيه أشياء
+
+254
+00:20:30,730 --> 00:20:33,990
+ليه ممكن نستوضحها من ال anterior view لازم نروح
+
+255
+00:20:33,990 --> 00:20:37,410
+للبستير وفي بعض الأشياء و الحركات لازم نشوفها من
+
+256
+00:20:37,410 --> 00:20:42,080
+ال lateral view وهذا كلهإن شاء الله مع التقدم
+
+257
+00:20:42,080 --> 00:20:48,780
+خلّينا في المساقات هتتعرفوا عليه لاحقا، شايفين؟
+
+258
+00:20:48,780 --> 00:20:51,320
+اللي هتضطرين عشان نقول Oxypetal bone أو الـ
+
+259
+00:20:51,320 --> 00:20:56,580
+أوكسبتالبون لازم نطلع عليها من posterior viewلازم
+
+260
+00:20:56,580 --> 00:21:01,180
+نطلع عليها من الخلف وهذه طبعا كل الأشياء اللي ممكن
+
+261
+00:21:01,180 --> 00:21:07,260
+نشوفها في جسم الإنسان من ال posterior view زي ال
+
+262
+00:21:07,260 --> 00:21:11,500
+occipital bone ال crania من ال posterior part
+
+263
+00:21:11,800 --> 00:21:15,800
+الـOlecranium of the elbow، المنطقة الـpupilial
+
+264
+00:21:15,800 --> 00:21:20,480
+part of the foot، هي الـleg، الـcalcaneus، لازم
+
+265
+00:21:20,480 --> 00:21:23,400
+نشوفها من الأمام، لازم نشوفها من الأعلى، حتى
+
+266
+00:21:23,400 --> 00:21:27,120
+بتلاقوا أن الصور هذه كلها مروسة بـstereo view
+
+267
+00:21:27,120 --> 00:21:30,660
+وanterior view، عشان نعرف إحنا من أنهي view، ممكن
+
+268
+00:21:30,660 --> 00:21:34,770
+نتطلع أو نشوف الأشياء هذه، الأشياء كتير مهمةحتى
+
+269
+00:21:34,770 --> 00:21:40,770
+احنا في خلال ان شاء الله اختبارنا لل .. للمادة و
+
+270
+00:21:40,770 --> 00:21:44,870
+ماذا تحصلكم المادة هتكون كتير أسئلة في المجال هذا
+
+271
+00:21:44,870 --> 00:21:48,490
+حتى تكونوا عندكوا قدرة معرفة الأشياء أنتي لما
+
+272
+00:21:48,490 --> 00:21:51,110
+بنطلع عليها بنطلع عليها من which view من ال
+
+273
+00:21:51,110 --> 00:21:55,800
+anterior ولا من ال posteriorطبعا لو قسمنا ال body
+
+274
+00:21:55,800 --> 00:22:01,060
+احنا بنقسم ال body لجزئين عندنا ال axial portion و
+
+275
+00:22:01,060 --> 00:22:06,620
+عندنا ال perpendicular ال axial هو الجسم عبارة عن
+
+276
+00:22:06,620 --> 00:22:13,090
+ال headمع ال neck, chest بيخلص من هنا بنسمي احنا
+
+277
+00:22:13,090 --> 00:22:17,790
+ال trunk يبقى ال head and neck and ال trunk أما ال
+
+278
+00:22:17,790 --> 00:22:22,110
+perpendicular ف means lower limb و ال upper limb
+
+279
+00:22:22,110 --> 00:22:26,110
+يعني ال arms و ال legs يعني الإيدين و الرجلين احنا
+
+280
+00:22:26,110 --> 00:22:29,980
+بالعرب بيقولهالكن ال upper limb كاملة و ال lower
+
+281
+00:22:29,980 --> 00:22:34,660
+limb كاملة عشان كل واحد من هذه الأشياء المكونات
+
+282
+00:22:34,660 --> 00:22:38,080
+تبع جسم الإنسان اللي أعطتها هي أو المنظر لجسم
+
+283
+00:22:38,080 --> 00:22:43,320
+الإنسان كل واحد منهم و وظيفته الخاصة اللي خلق من
+
+284
+00:22:43,320 --> 00:22:47,080
+.. من أجلها طبعا في ال axial portion في عنا
+
+285
+00:22:47,080 --> 00:22:51,820
+cavities هذه ال cavities لازم احنا نتعرف عليها و
+
+286
+00:22:51,820 --> 00:22:56,400
+نكون وعين لإلها في عنا ال cranial cavityلأن هذه
+
+287
+00:22:56,400 --> 00:23:00,740
+العيون الجمجمة اللي بتحتوي على عضو مهم جدا من
+
+288
+00:23:00,740 --> 00:23:05,320
+أعضاء الجسم اللي هو ال brain، ال brain عشان هيك ال
+
+289
+00:23:05,320 --> 00:23:08,800
+brain محط بالأذام، يعني وظيفة الأذام هنجي في مساقل
+
+290
+00:23:08,800 --> 00:23:12,820
+.. لما نجي نوصل ل ال skeletal system إيش وظيفته؟
+
+291
+00:23:12,820 --> 00:23:20,310
+وظيفته إنهيحافظ على الأحشاء أو الحشوات اللي موجودة
+
+292
+00:23:20,310 --> 00:23:23,490
+فيه، يعني ال cranium بتحافظ على ال brain ال
+
+293
+00:23:23,490 --> 00:23:27,090
+vertebral canal هذه اللي موجودة في ال vertebral
+
+294
+00:23:27,090 --> 00:23:31,350
+column بتحافظ على ال spinal cordأما هذه الأشياء
+
+295
+00:23:31,350 --> 00:23:34,630
+اللي بنشوفها احنا من الخلق أما من الأمام إيش بيكون
+
+296
+00:23:34,630 --> 00:23:37,250
+فيها ثرس ال cavity ثرس ال cavity اللي بتطلع من
+
+297
+00:23:37,250 --> 00:23:40,530
+الأمام بتطلع أنا بتخيل لو شلط العضم هذا وفتحته
+
+298
+00:23:40,530 --> 00:23:43,530
+بهذا الشكل إيش بيكون جوا؟ بيكون ال lungs
+
+299
+00:23:43,530 --> 00:23:47,650
+المديستينة الthymus ال heart ال oesophagus
+
+300
+00:23:47,650 --> 00:23:52,830
+التراكيا كل هذه cavities موجودة في ال
+
+301
+00:23:55,420 --> 00:23:59,420
+الـ cavity اللى موجودة بتاعة ال chest cavity أما
+
+302
+00:23:59,420 --> 00:24:03,340
+ال abdominal pelvic فطبعا احنا بطلع على منطقة ال
+
+303
+00:24:03,340 --> 00:24:06,500
+abdominal cavity بكون فيه لنا ال stomach و ال
+
+304
+00:24:06,500 --> 00:24:09,960
+liver و سلين و جوا ال brother ال intestine سواء
+
+305
+00:24:09,960 --> 00:24:15,040
+large أو small intestine يعني كل اللى بنسميهم احنا
+
+306
+00:24:15,040 --> 00:24:20,980
+الأحشاءبال .. بالعربي، المعدة و الكبد و الطحال و
+
+307
+00:24:20,980 --> 00:24:25,780
+الأمعاء الغليظة و الأمعاء الرفيعة و المرارة و كل
+
+308
+00:24:25,780 --> 00:24:30,080
+الأشياء هذه اللي بتكون موجودة، حتى الواحد لما بيتج
+
+309
+00:24:30,080 --> 00:24:34,100
+عملية، لما بيتج عملية في الأحجاق، بيروحوا بيفتحوا
+
+310
+00:24:34,100 --> 00:24:37,440
+بطنهأما احتاج عملية في الرأس بيفتحوا ال cranium
+
+311
+00:24:37,440 --> 00:24:40,220
+احتاج عملية مثلا في ال spinal cord بيفتحوا ال
+
+312
+00:24:40,220 --> 00:24:43,300
+spinal فحتى ال position اللى بنوضع فيه المريض
+
+313
+00:24:43,300 --> 00:24:49,800
+هيختلف طبعا هيروح يفوت ل ال cranium من الخلفأو لـ
+
+314
+00:24:49,800 --> 00:24:53,240
+Spinal cord بتنام المريض على بطنه عشان يعرف يشتغل
+
+315
+00:24:53,240 --> 00:24:56,280
+أما هنا لو بنعمل abdominal surgery بتنام المريض
+
+316
+00:24:56,280 --> 00:24:59,480
+على دهره و احنا بنبقى عارفين حتى ال positions هذه
+
+317
+00:24:59,480 --> 00:25:04,460
+كيف بدوا يتعامل معها الأخصائين أو الجرحين في هذا
+
+318
+00:25:04,460 --> 00:25:07,720
+لما بدوا يفوت لانهي cavity من هذه ال cavities من
+
+319
+00:25:07,720 --> 00:25:12,600
+انهي position هو بده يفوت منطقة البلفد cavity اللي
+
+320
+00:25:12,600 --> 00:25:16,600
+هي منطقة الحوت بتحتوي على ال urinaryالـ Bladder
+
+321
+00:25:16,600 --> 00:25:21,720
+اللي هي المثانا و كل ال internal reproductive for
+
+322
+00:25:21,720 --> 00:25:26,640
+male and female و طبعا هذا كله هنتكلم عليه في ال
+
+323
+00:25:26,640 --> 00:25:31,620
+musculoskeletal system طبعا ال diaphragm هي عبارة
+
+324
+00:25:31,620 --> 00:25:37,680
+عن عضلةتقسم ال cavities اللي موجودة جوا ل upper
+
+325
+00:25:37,680 --> 00:25:42,240
+and lower دي افراج هي عضلة التنفس ال main
+
+326
+00:25:42,240 --> 00:25:47,520
+respiratory muscle اللي احنا لما بناخدInspiration
+
+327
+00:25:47,520 --> 00:25:51,280
+هي بصيرها contraction بتوسع ال thoracic cavity هذه
+
+328
+00:25:51,280 --> 00:25:55,200
+بتخلي الهوى يدخل، لكن هذه العضلة إيش وظفتها؟ بتعمل
+
+329
+00:25:55,200 --> 00:25:58,380
+.. بتلعب دور أساسي في عملية التنفس وكمان بتلعب دور
+
+330
+00:25:58,380 --> 00:26:01,880
+أساسي بالفصل بين ال cavities اللي موجودة في الجسم
+
+331
+00:26:01,880 --> 00:26:07,260
+ال abdominal cavity و thoracic cavityطبعا ال
+
+332
+00:26:07,260 --> 00:26:10,540
+kidney و ال adrenal gland و ال pancreas و ال
+
+333
+00:26:10,540 --> 00:26:15,640
+ureters are behind the abdominal pelvic cavity هى
+
+334
+00:26:15,640 --> 00:26:24,340
+موجودة فى البطن بس شوية لورا طبعا هذا رسم توضيحى ل
+
+335
+00:26:24,340 --> 00:26:30,480
+ال ventral cavity فى أن هي ال thoracicو ال
+
+336
+00:26:30,480 --> 00:26:33,380
+diaphragm اللى هى العضله هادى اللى بتقسم بين ال
+
+337
+00:26:33,380 --> 00:26:37,660
+abdomen and chest و هاد ال abdomen هاد ال cavity و
+
+338
+00:26:37,660 --> 00:26:41,380
+هاد ال pelvic cavity بتكون كتير lower فى منطقه
+
+339
+00:26:41,380 --> 00:26:46,390
+الحوض فبسموها abdomen و pelvic cavityهنا من ال
+
+340
+00:26:46,390 --> 00:26:49,050
+anterior view هنا اللى موجودة فى ال anterior side
+
+341
+00:26:49,050 --> 00:26:52,370
+بتيجى عندنا الحد و العلامة تبعتنا للبستيرور فى
+
+342
+00:26:52,370 --> 00:26:55,830
+عندنا ال cranial cavity و فى عندنا ال vertebral
+
+343
+00:26:55,830 --> 00:26:59,850
+cavity اللى هى بتحتوي على ال spinal cord و فوق
+
+344
+00:26:59,850 --> 00:27:02,830
+بتحتوي على ال brain
+
+345
+00:27:08,400 --> 00:27:12,540
+وها دراسة توضيحي أكتر برضه بيوضحلنا كل الأشياء
+
+346
+00:27:12,540 --> 00:27:16,140
+اللي احنا اتكلمنا عليها قبل شوية سواء اللي في
+
+347
+00:27:16,140 --> 00:27:20,740
+عندنا طبعا نتكلم على ال chest cavity فيها تحتوي
+
+348
+00:27:20,740 --> 00:27:26,680
+على ال right و left lungs ال heart المديستينم اللي
+
+349
+00:27:26,680 --> 00:27:31,580
+في عندنا ال plural cavity في عندنا ال diaphragm
+
+350
+00:27:31,580 --> 00:27:35,880
+اللي هو شايفين تفصل هذه المنطقة عن تفصل ال chest
+
+351
+00:27:35,880 --> 00:27:36,900
+عن ال abdomen
+
+352
+00:27:44,820 --> 00:27:49,480
+هنروح على ال membranes اللي موجودة جوا، طبعا هي ال
+
+353
+00:27:49,480 --> 00:27:52,700
+membranes هي عبارة عن الأغشية اللي بتحيط في
+
+354
+00:27:52,700 --> 00:27:56,560
+الأنسجة، في عندنا نوعين من ال membranes ال
+
+355
+00:27:56,560 --> 00:28:00,020
+visceral و في ال parietal، ال visceral هو اللي
+
+356
+00:28:00,020 --> 00:28:05,520
+بحيط الأحشاء نفسها، أما ال parietal فهي بتحيط ال
+
+357
+00:28:05,520 --> 00:28:12,130
+body cavity نفسها طبعاال .. هدول الأنسجة ..
+
+358
+00:28:12,130 --> 00:28:15,810
+الأنسجة في عندنا طبقتين من الأنسجة وما بين هدول
+
+359
+00:28:15,810 --> 00:28:19,110
+الطبقتين في عندنا حاجة اسمها Cirrus .. Cirrus
+
+360
+00:28:19,110 --> 00:28:23,750
+Fluid Cirrus Fluid هذا إيش وظيفته؟ وظيفته إنه يعمل
+
+361
+00:28:23,750 --> 00:28:29,910
+lubricants يمنع الاحتكاك يرتب ال .. المكان حتى
+
+362
+00:28:29,910 --> 00:28:34,170
+يساعد على .. فإحنا إذا بناخد نفس بتتوسع ال chest
+
+363
+00:28:34,170 --> 00:28:40,710
+صحيح؟بتحاط ال lungs في ال plural membrane بتكون
+
+364
+00:28:40,710 --> 00:28:44,430
+على أساس إنه ما بين ال plural و ال parietal بيكون
+
+365
+00:28:44,430 --> 00:28:50,770
+في عندنا ال serous effluent يبقى soft، thin
+
+366
+00:28:51,270 --> 00:28:56,110
+Playable layers of tissue that either يأما cover
+
+367
+00:28:56,110 --> 00:28:59,890
+ال vital أو ال visceral organ اللي هي موجودة في
+
+368
+00:28:59,890 --> 00:29:03,950
+الداخل اللي هي الحشوية أو الأحشاء ال parietal اللي
+
+369
+00:29:03,950 --> 00:29:08,430
+هي الجسدية اللي بتكون لبرا lines او body cavity هي
+
+370
+00:29:08,430 --> 00:29:11,910
+ال parietal membrane
+
+371
+00:29:13,420 --> 00:29:17,600
+طبعا هان هيوضح لنا كل membrane من الموجودين سواء
+
+372
+00:29:17,600 --> 00:29:23,060
+في ال lungs، سواء في ال heart، سواء في ال viscera،
+
+373
+00:29:23,060 --> 00:29:26,340
+إيش هو؟ there are specific names for membranes
+
+374
+00:29:26,340 --> 00:29:30,360
+around ال heart و ال lungs و ال abdominal organs،
+
+375
+00:29:30,360 --> 00:29:34,800
+في عناالـ Serious membrane of the lungs كلنا سمعنا
+
+376
+00:29:34,800 --> 00:29:39,240
+يوما ما عن البلورة، في عندنا الviscera البلورة
+
+377
+00:29:39,240 --> 00:29:44,640
+اللى محيط باللغة نفسها فاسمها viscera البلورة أما
+
+378
+00:29:44,640 --> 00:29:48,340
+ال lines ده cavity in which the lung located يعني
+
+379
+00:29:48,340 --> 00:29:52,730
+عند ال chest cage نفسه فاسمها parietal بلورةin
+
+380
+00:29:52,730 --> 00:29:57,210
+between فى عندنا هذا ال fluid اللى فى ال Cerase
+
+381
+00:29:57,210 --> 00:30:01,530
+Fluid او الغشاء او السائل المصلي اللى بيكون بيساعد
+
+382
+00:30:01,530 --> 00:30:06,970
+على ال lupricants للمكان يعنى احنا فى عندنا بلورة
+
+383
+00:30:06,970 --> 00:30:11,810
+هذا البلورة الجزء المحيط بال lung اسمه فزيرالبلورة
+
+384
+00:30:11,810 --> 00:30:17,870
+اما الجزء الملاسق لعضمات ال ribs و عضمة القصفة فهى
+
+385
+00:30:17,870 --> 00:30:23,000
+اسمها Parietal Blura الجزء الخارجىبيكون، يعني
+
+386
+00:30:23,000 --> 00:30:26,860
+الداخل اللي حوالين الأحشاء بيكون اسمه visceral أما
+
+387
+00:30:26,860 --> 00:30:31,040
+الخارج بيكون هو parietal، لكن إحنا إنه بنشوفهم
+
+388
+00:30:31,040 --> 00:30:35,810
+كإنهم عندنا الرأس نضيح يورجينا إيه يعني؟أما الـ
+
+389
+00:30:35,810 --> 00:30:40,310
+heart في عيننا visceral بريكارديام هو الملاصق that
+
+390
+00:30:40,310 --> 00:30:43,670
+membrane lines the cavity in which the heart is
+
+391
+00:30:43,670 --> 00:30:47,870
+located اسمه البرايتل، الvisceral بيكون ملاصق لل
+
+392
+00:30:47,870 --> 00:30:53,710
+heart أما البرايتل فهو ملاصق للجزء أو المكان اللي
+
+393
+00:30:53,710 --> 00:31:00,090
+موجود في ال heart وطبعا in between بيكون ال serous
+
+394
+00:31:00,090 --> 00:31:06,070
+fluidهدولة كتير مهم إحنا نقرا، يبقى فيه عندنا
+
+395
+00:31:06,070 --> 00:31:08,850
+pericardium visceral وفيه عندنا pericardium
+
+396
+00:31:08,850 --> 00:31:12,090
+parietal و in between في عندنا حاجة اسمها
+
+397
+00:31:12,090 --> 00:31:16,050
+pericardial cavity، هذه موجودة بين ال visceral و
+
+398
+00:31:16,050 --> 00:31:18,610
+ال parietal membrane اللي هو إحنا بنسميهم ال
+
+399
+00:31:18,610 --> 00:31:22,530
+pericardium كلمة بني معناها محيط، يعني الغلاف
+
+400
+00:31:22,530 --> 00:31:29,390
+الخارجي لعضلة القلبأما ال abdominal area فعنا فيه
+
+401
+00:31:29,390 --> 00:31:34,730
+ال visceral portion هذه بتكون على ال surface بتكون
+
+402
+00:31:34,730 --> 00:31:37,870
+محيطة بالأحجار اللي هي زي ال lung زي ال liver زي
+
+403
+00:31:37,870 --> 00:31:41,450
+السلين و غيرهم أما ال visceral portion بتكون ناحيت
+
+404
+00:31:41,450 --> 00:31:45,990
+للخارج أكتر ال parietal قصدي فهي بتحيط ال
+
+405
+00:31:45,990 --> 00:31:50,610
+abdominal cavity بصفة عامة و بتتسمى ال peritoneum
+
+406
+00:31:50,610 --> 00:31:55,440
+يبقى parietal اسمهاالـ Visceral Peritoneum
+
+407
+00:31:55,440 --> 00:32:00,300
+والبرايتل البريتونيوم والكافيتى اسمها Peritoneal
+
+408
+00:32:00,300 --> 00:32:04,360
+Cavity اللى موجود فيها السائل المصلي او الـ Serous
+
+409
+00:32:04,360 --> 00:32:08,960
+اذا فلوت وطبعا الرسم التوضيحى هذا بالتدقيق فيه
+
+410
+00:32:08,960 --> 00:32:13,820
+هلاقي ان فيه اكتر من ممبران ممبران ملاصق مثلا للـ
+
+411
+00:32:13,820 --> 00:32:17,800
+lungs وممبران على الجزء الخارجى و بينهم full of
+
+412
+00:32:18,070 --> 00:32:23,430
+اللي هو ال sirus fluid وهذه عضلة في القلب اللي
+
+413
+00:32:23,430 --> 00:32:27,210
+انتوا شايفيها برضه فيها اكتر من مبرنة، المبرنة
+
+414
+00:32:27,210 --> 00:32:31,690
+الملاصقة بريكارديا و البرايتل بريكارديا و بالنص ال
+
+415
+00:32:31,690 --> 00:32:34,030
+sirus fluid
+
+416
+00:32:42,240 --> 00:32:47,460
+وهذا الرسم يعني بالألوان بيوضح أكتر عمليات الفصل
+
+417
+00:32:47,460 --> 00:32:52,840
+هذه ما بين الأحشاء الداخلية حتى ما تختلط مع بعضها
+
+418
+00:32:52,840 --> 00:32:56,580
+لحظة تسمع كتير أنه في واحد والله عنده فتق في
+
+419
+00:32:56,580 --> 00:33:01,440
+الحجاب الحاجز في عنده حاجة pleuritis في حاجة اسمها
+
+420
+00:33:01,440 --> 00:33:05,160
+pneumonia في حاجة اسمها يعني أشياء pneumothorax
+
+421
+00:33:05,160 --> 00:33:09,240
+معناه أنه فيه دخل الهواء على منطقة البلورة وعملوا
+
+422
+00:33:09,240 --> 00:33:13,450
+هذه المشاكل كلها بتكون مؤلمةو مزعجة و لو مثلا صار
+
+423
+00:33:13,450 --> 00:33:18,510
+فيه النفاتق في أحد الأغش هذه و طلع القضوء منه
+
+424
+00:33:18,510 --> 00:33:23,010
+بيسبب قلم كتير و بيعمل ارتجاع و مشكلات كتير كتير
+
+425
+00:33:23,010 --> 00:33:28,630
+طبعا قسموا عشان يسهلوا عملية الوصف للأحشاء و عملية
+
+426
+00:33:28,630 --> 00:33:33,020
+قدرة ال .. ال .. خدعنا نقول ال surgeons اللياللي
+
+427
+00:33:33,020 --> 00:33:36,960
+هم الجرحين على أنهم يدخلوا المناطق فقسموه ال
+
+428
+00:33:36,960 --> 00:33:42,180
+abdominal لأربع quadrant يعني لأربع أربع طبعا في
+
+429
+00:33:42,180 --> 00:33:45,960
+عندنا ال upper و في عندنا ال lower ففي طالما احنا
+
+430
+00:33:45,960 --> 00:33:48,940
+بنتكلم عن upper و عن lower و في عندنا left و في
+
+431
+00:33:48,940 --> 00:33:52,520
+عندنا right فصار في عندنا ال upper right upper
+
+432
+00:33:52,520 --> 00:33:56,600
+quadrant اللي هو بيكون فوق عندنا right lower
+
+433
+00:33:56,600 --> 00:34:00,880
+quadrant اللي بيكون لتحت و كذلك left upper و left
+
+434
+00:34:00,880 --> 00:34:08,030
+lowerو هذه طبعا هذه التقسيمة بتساعدي كتير في تحديد
+
+435
+00:34:08,030 --> 00:34:11,590
+المشكلات وين موجودة ال location تبع الأحشاء اللي
+
+436
+00:34:11,590 --> 00:34:14,770
+موجودة اللي من خلالها لو كان في ألم معين لو كان
+
+437
+00:34:14,770 --> 00:34:18,790
+inflammation معين نقدر نحدد المكان هذا إيش موجود
+
+438
+00:34:18,790 --> 00:34:23,510
+فيه و نقدر نشخص المشكلات اللي ممكن يواجهها الصحية
+
+439
+00:34:23,510 --> 00:34:26,390
+اللي موجهها الأشخاص طبعا في عندنا الفيسر في عندنا
+
+440
+00:34:26,390 --> 00:34:30,630
+ال midlineو هنا عاملين خط على أساس transversal
+
+441
+00:34:30,630 --> 00:34:36,230
+plan فبيقسم هذه لأربع أربع هذا بالنسبة ل ال
+
+442
+00:34:36,230 --> 00:34:44,190
+abdominal طبعا قسموا ال abdomen ل regions و هاد ال
+
+443
+00:34:44,190 --> 00:34:50,010
+regions طبعا عملوها تسعة regionsويلها مسمياتها
+
+444
+00:34:50,010 --> 00:34:53,210
+الخاصة طبعا في منها ال left و في منها ال right و
+
+445
+00:34:53,210 --> 00:34:56,990
+فيها الأشياء اللي موجودة في ال .. الوسط زي ال
+
+446
+00:34:56,990 --> 00:35:00,630
+amplitus region منطقة الصرة احنا بنسميها هذه بتكون
+
+447
+00:35:00,630 --> 00:35:06,410
+في وسط ال abdominal cavity هذه لحالها أخدت عملت
+
+448
+00:35:06,410 --> 00:35:13,320
+رقم فردي خلينا نسميهال .. ال other divisions أو
+
+449
+00:35:13,320 --> 00:35:18,040
+other regions زي ال right hypochondric region
+
+450
+00:35:18,040 --> 00:35:24,620
+منطقة لتحت ال ribs سموها right hypochondric region
+
+451
+00:35:24,620 --> 00:35:27,780
+منطقة ال lumber ال lumber احنا بنعرف منطقة ال back
+
+452
+00:35:27,780 --> 00:35:30,260
+او lower lower back ال lumber region او المنطقة
+
+453
+00:35:30,260 --> 00:35:34,080
+القطانية هذه ففي هذه المنطقة سموها ال right lumber
+
+454
+00:35:34,080 --> 00:35:37,580
+regionوالرايت الياك انجوايل المنطقة الانجوايل
+
+455
+00:35:37,580 --> 00:35:42,100
+الهادي اللي هي فيها كتير من ال blood vessels و ال
+
+456
+00:35:42,100 --> 00:35:47,020
+arteries و ال vein و ال lymph nodes و غيرها في
+
+457
+00:35:47,020 --> 00:35:53,490
+عندنا ال epigastric منطقة الالأعلى المعدة اللي هي
+
+458
+00:35:53,490 --> 00:35:57,850
+واضحة عنا بهذا الشكل هنا هنا الambulicus ال hypo
+
+459
+00:35:57,850 --> 00:36:05,210
+hypo gastric تحت المعدة و ال lift هلاقيتها بنرجع
+
+460
+00:36:05,210 --> 00:36:11,310
+مرة تانيةالكندرياك و ال .. و ال lumber region و ال
+
+461
+00:36:11,310 --> 00:36:16,530
+.. و ال .. و ال Iliac region بس على ال left side
+
+462
+00:36:16,530 --> 00:36:20,670
+عشان هيك صاروا فيه عندنا تسعة regions احنا بنتكلم
+
+463
+00:36:20,670 --> 00:36:28,440
+عنهم وهذه الصورة بتوضح أكتر المناطقوين وجودها هي
+
+464
+00:36:28,440 --> 00:36:32,700
+ال ابكاسترك حوالين المعدة الامبالايتس حوالين اللي
+
+465
+00:36:32,700 --> 00:36:36,960
+هي السرعة ال pubic region منطقة اللي هي الحوض أو
+
+466
+00:36:36,960 --> 00:36:41,700
+أسفل البطن ال right groin منطقة ال groin المنطقة
+
+467
+00:36:41,700 --> 00:36:46,620
+هذه اللي موجودة في الجسم و ال hypochondriac ال
+
+468
+00:36:46,620 --> 00:36:52,680
+right and left hypochondriacان شاء الله تكون هاي
+
+469
+00:36:52,680 --> 00:36:57,300
+اخر محاضرة اخر slide لعينها طبعا بشكركم ان شاء
+
+470
+00:36:57,300 --> 00:37:00,420
+الله على حسن استماعك و بتمنا ان هاي المحاضرات تكون
+
+471
+00:37:00,420 --> 00:37:04,320
+مفيدة للكم و اي استفسار انا نزلت على المجموعة ال
+
+472
+00:37:04,320 --> 00:37:08,340
+whats اني انا موجودة بكون يوم سبت و اتنين في
+
+473
+00:37:08,340 --> 00:37:12,400
+الجامعة اي حد بحب يتواصل معايا اهلا و سهلا و
+
+474
+00:37:12,400 --> 00:37:13,200
+يعطيكم العافية
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..3020fd7b0ca4cb4306261e73c141abfc61fbbe4c
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM_raw.json
@@ -0,0 +1 @@
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نفضها بعد هيك في مجال العلوم الصحية و يفضل إنه احنا نكون حافظينها by heart لإن هي شغلات صحيحة احنا اليوم هنكون عندنا دور في فهمها", "tokens": [6027, 21618, 298, 804, 27575, 29538, 3714, 16095, 3660, 5296, 28814, 1863, 3224, 8032, 2655, 1863, 3555, 22653, 25894, 11296, 28242, 9673, 12984, 4587, 5172, 9307, 18863, 42213, 10632, 4032, 28239, 19913, 2288, 10632, 13672, 1829, 47525, 8315, 8717, 5172, 11242, 11296, 39182, 39896, 4117, 8978, 3714, 7435, 6027, 18863, 1211, 20498, 31767, 5016, 10632, 4032, 7251, 5172, 11242, 1211, 36145, 3224, 1975, 5016, 8315, 8717, 30544, 11331, 31845, 19913, 9957, 11296, 538, 1917, 5296, 28814, 1863, 39896, 13412, 17082, 1211, 9307, 20328, 5016, 1829, 5016, 3660, 1975, 5016, 8315, 45595, 20498, 8032, 1863, 30544, 43242, 8315, 11778, 13063, 8978, 6156, 16095, 11296], "avg_logprob": -0.16616587183223322, "compression_ratio": 1.6785714285714286, "no_speech_prob": 2.4437904357910156e-06, "words": [{"start": 44.77, "end": 45.23, "word": "ال", "probability": 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" اقتربنا", "probability": 0.9556884765625}, {"start": 653.54, "end": 653.78, "word": " إلى", "probability": 0.421630859375}, {"start": 653.78, "end": 654.44, "word": " ال", "probability": 0.8251953125}, {"start": 654.44, "end": 655.0, "word": " cranial", "probability": 0.96630859375}, {"start": 655.0, "end": 655.34, "word": " فهو", "probability": 0.8955078125}, {"start": 655.34, "end": 655.82, "word": " بنسميه", "probability": 0.8790283203125}, {"start": 655.82, "end": 656.36, "word": " cranial", "probability": 0.980224609375}, {"start": 656.36, "end": 656.82, "word": " أما", "probability": 0.739501953125}, {"start": 656.82, "end": 657.2, "word": " codal", "probability": 0.78564453125}, {"start": 657.2, "end": 657.56, "word": " بنروح", "probability": 0.8818359375}, {"start": 657.56, "end": 657.9, "word": " ناحية", "probability": 0.7117513020833334}, {"start": 657.9, "end": 658.44, "word": " الذيل", "probability": 0.758544921875}, {"start": 658.44, "end": 659.22, "word": " بتعرفوا", 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77886, "start": 751.0, "end": 778.86, "text": "في بعض المصطلحات أو لما بنوصف بعض الأنسجة اللي موجودة في الجسم ممكن تكون في لحظة هي deep و لحظة تكون superficial يعني بتكون هي deep in relation to other tissue زي ال bone، deep in relation to the muscle ال muscle deeper than the skin like skin superficial ال muscle superficial than bone وهدي .. هذا اللي بيلزمنا احنا لما نتعرف على هذه ال terminology", "tokens": [41185, 45030, 11242, 9673, 9381, 9566, 1211, 5016, 9307, 34051, 5296, 15042, 44945, 2407, 9381, 5172, 45030, 11242, 16247, 1863, 3794, 7435, 3660, 13672, 1829, 3714, 29245, 23328, 3660, 8978, 25724, 38251, 3714, 43020, 6055, 30544, 8978, 5296, 5016, 19913, 3660, 39896, 2452, 4032, 5296, 5016, 19913, 3660, 6055, 30544, 34622, 37495, 22653, 39894, 30544, 39896, 2452, 294, 9721, 281, 661, 12404, 30767, 1829, 2423, 9026, 12399, 2452, 294, 9721, 281, 264, 8679, 2423, 8679, 7731, 813, 264, 3178, 411, 3178, 34622, 2423, 8679, 34622, 813, 9026, 37037, 16254, 4386, 23758, 13672, 1829, 4724, 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عملية مثلا في ال spinal cord بيفتحوا ال spinal فحتى ال position اللى بنوضع فيه المريض هيختلف طبعا هيروح يفوت ل ال cranium من الخلف", "tokens": [10721, 15042, 1975, 33753, 26108, 6225, 42213, 10632, 8978, 34892, 10721, 3794, 4724, 33911, 2655, 5016, 14407, 2423, 941, 21528, 1975, 33753, 26108, 6225, 42213, 10632, 50113, 15040, 8978, 2423, 28022, 12250, 4724, 33911, 2655, 5016, 14407, 2423, 28022, 6156, 33753, 7578, 2423, 2535, 13672, 7578, 44945, 2407, 11242, 3615, 8978, 3224, 9673, 16572, 11242, 39896, 46456, 46538, 23032, 3555, 3615, 995, 8032, 13546, 2407, 5016, 7251, 5172, 35473, 5296, 2423, 941, 21528, 9154, 33962, 46538], "avg_logprob": -0.1774553641096338, "compression_ratio": 1.680232558139535, "no_speech_prob": 1.138448715209961e-05, "words": [{"start": 1474.96, "end": 1475.18, "word": "أما", "probability": 0.5648193359375}, {"start": 1475.18, "end": 1475.52, "word": " احتاج", "probability": 0.8020833333333334}, {"start": 1475.52, "end": 1475.96, "word": " عملية", 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0.974609375}], "temperature": 1.0}, {"id": 100, "seek": 223319, "start": 2210.76, "end": 2233.2, "text": "ان شاء الله تكون هاي اخر محاضرة اخر slide لعينها طبعا بشكركم ان شاء الله على حسن استماعك و بتمنا ان هاي المحاضرات تكون مفيدة للكم و اي استفسار انا نزلت على المجموعة ال whats اني انا موجودة بكون يوم سبت و اتنين في الجامعة اي حد بحب يتواصل معايا اهلا و سهلا و يعطيكم العافية", "tokens": [7649, 13412, 16606, 21984, 6055, 30544, 8032, 47302, 1975, 34740, 3714, 5016, 46958, 25720, 1975, 34740, 4137, 5296, 3615, 9957, 11296, 23032, 3555, 3615, 995, 4724, 8592, 37983, 24793, 16472, 13412, 16606, 21984, 15844, 11331, 3794, 1863, 44713, 15042, 3615, 4117, 4032, 4724, 39237, 8315, 16472, 8032, 47302, 9673, 5016, 46958, 2288, 9307, 6055, 30544, 3714, 5172, 25708, 3660, 5296, 23275, 2304, 4032, 1975, 1829, 44713, 36178, 9640, 1975, 8315, 8717, 11622, 1211, 2655, 15844, 9673, 7435, 2304, 2407, 27884, 2423, 29625, 16472, 1829, 1975, 8315, 3714, 29245, 23328, 3660, 4724, 30544, 7251, 20498, 8608, 3555, 2655, 4032, 1975, 2655, 1863, 9957, 8978, 25724, 10943, 27884, 1975, 1829, 11331, 3215, 4724, 5016, 3555, 7251, 2655, 2407, 33546, 1211, 20449, 995, 25528, 1975, 3224, 15040, 4032, 8608, 3224, 15040, 4032, 37495, 9566, 1829, 24793, 18863, 31845, 10632], "avg_logprob": -0.1665146020207092, "compression_ratio": 1.8858267716535433, "no_speech_prob": 6.341934204101562e-05, "words": [{"start": 2210.76, "end": 2211.0, "word": "ان", "probability": 0.58349609375}, {"start": 2211.0, "end": 2211.1, "word": " شاء", "probability": 0.746337890625}, {"start": 2211.1, "end": 2211.2, "word": " الله", "probability": 0.96142578125}, {"start": 2211.2, "end": 2211.64, "word": " تكون", "probability": 0.9072265625}, {"start": 2211.64, "end": 2212.68, "word": " هاي", "probability": 0.6485595703125}, {"start": 2212.68, "end": 2213.3, "word": " اخر", "probability": 0.7493896484375}, {"start": 2213.3, "end": 2213.88, "word": " محاضرة", "probability": 0.9627685546875}, {"start": 2213.88, "end": 2214.4, "word": " اخر", "probability": 0.7257080078125}, {"start": 2214.4, "end": 2215.12, "word": " slide", "probability": 0.97412109375}, {"start": 2215.12, "end": 2215.66, "word": " لعينها", "probability": 0.6998291015625}, {"start": 2215.66, "end": 2216.42, "word": " طبعا", "probability": 0.91259765625}, {"start": 2216.42, "end": 2217.04, "word": " بشكركم", "probability": 0.76422119140625}, {"start": 2217.04, "end": 2217.18, "word": " ان", "probability": 0.673828125}, {"start": 2217.18, "end": 2217.3, "word": " شاء", "probability": 0.994873046875}, {"start": 2217.3, "end": 2217.5, "word": " الله", "probability": 0.9609375}, {"start": 2217.5, "end": 2217.74, "word": " على", "probability": 0.94287109375}, {"start": 2217.74, "end": 2217.98, "word": " حسن", "probability": 0.9781901041666666}, {"start": 2217.98, "end": 2218.48, "word": " استماعك", "probability": 0.8990478515625}, {"start": 2218.48, "end": 2218.56, "word": " و", "probability": 0.6953125}, {"start": 2218.56, "end": 2218.92, "word": " بتمنا", "probability": 0.5386555989583334}, {"start": 2218.92, "end": 2219.06, "word": " ان", "probability": 0.93017578125}, {"start": 2219.06, "end": 2219.3, "word": " هاي", "probability": 0.7861328125}, {"start": 2219.3, "end": 2219.96, "word": " المحاضرات", "probability": 0.94931640625}, {"start": 2219.96, "end": 2220.42, "word": " تكون", "probability": 0.94091796875}, {"start": 2220.42, "end": 2221.28, "word": " مفيدة", "probability": 0.98876953125}, {"start": 2221.28, "end": 2221.72, "word": " للكم", "probability": 0.7351888020833334}, {"start": 2221.72, "end": 2221.82, "word": " و", "probability": 0.60302734375}, {"start": 2221.82, "end": 2221.98, "word": " اي", "probability": 0.837890625}, {"start": 2221.98, "end": 2222.58, "word": " استفسار", "probability": 0.98193359375}, {"start": 2222.58, "end": 2222.84, "word": " انا", "probability": 0.900390625}, {"start": 2222.84, "end": 2223.36, "word": " نزلت", "probability": 0.9813232421875}, {"start": 2223.36, "end": 2223.54, "word": " على", "probability": 0.75244140625}, {"start": 2223.54, "end": 2224.14, "word": " المجموعة", "probability": 0.860546875}, {"start": 2224.14, "end": 2224.32, "word": " ال", "probability": 0.97900390625}, {"start": 2224.32, "end": 2224.66, "word": " whats", "probability": 0.204345703125}, {"start": 2224.66, "end": 2225.64, "word": " اني", "probability": 0.71728515625}, {"start": 2225.64, "end": 2225.78, "word": " انا", "probability": 0.85791015625}, {"start": 2225.78, "end": 2226.22, "word": " موجودة", "probability": 0.974365234375}, {"start": 2226.22, "end": 2226.56, "word": " بكون", "probability": 0.956787109375}, {"start": 2226.56, "end": 2226.78, "word": " يوم", "probability": 0.9892578125}, {"start": 2226.78, "end": 2227.28, "word": " سبت", "probability": 0.79736328125}, {"start": 2227.28, "end": 2227.64, "word": " و", "probability": 0.97021484375}, {"start": 2227.64, "end": 2228.2, "word": " اتنين", "probability": 0.925537109375}, {"start": 2228.2, "end": 2228.34, "word": " في", "probability": 0.86474609375}, {"start": 2228.34, "end": 2228.78, "word": " الجامعة", "probability": 0.9912109375}, {"start": 2228.78, "end": 2229.0, "word": " اي", "probability": 0.880615234375}, {"start": 2229.0, "end": 2229.18, "word": " حد", "probability": 0.986572265625}, {"start": 2229.18, "end": 2229.46, "word": " بحب", "probability": 0.9402669270833334}, {"start": 2229.46, "end": 2230.0, "word": " يتواصل", "probability": 0.962109375}, {"start": 2230.0, "end": 2230.6, "word": " معايا", "probability": 0.9913736979166666}, {"start": 2230.6, "end": 2231.94, "word": " اهلا", "probability": 0.84326171875}, {"start": 2231.94, "end": 2232.08, "word": " و", "probability": 0.9111328125}, {"start": 2232.08, "end": 2232.3, "word": " سهلا", "probability": 0.9334309895833334}, {"start": 2232.3, "end": 2232.4, "word": " و", "probability": 0.962890625}, {"start": 2232.4, "end": 2232.72, "word": " يعطيكم", "probability": 0.7835693359375}, {"start": 2232.72, "end": 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\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..e635b758319fd5582e9a0de7edcf4f1ee372ca4f
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/I5E2rJvQ3pM_raw.srt
@@ -0,0 +1,1896 @@
+1
+00:00:05,010 --> 00:00:09,350
+بسم الله الرحمن الرحيم لمحاضرتنا اليوم التانية في
+
+2
+00:00:09,350 --> 00:00:15,290
+مساق ال anatomy المحاضرة السابقة اتعرفنا عليها
+
+3
+00:00:15,290 --> 00:00:18,530
+تعريف ال anatomy و ال physiology اليوم هتعرف على
+
+4
+00:00:18,530 --> 00:00:21,550
+بعض ال terminology اللي احنا عادة بنستخدمها في
+
+5
+00:00:21,550 --> 00:00:24,950
+مجال ال anatomy اللي بننجره منكوا طبعا كطلاب ان
+
+6
+00:00:24,950 --> 00:00:30,880
+شاء الله تكونوا حافظينها لآخر يومفي عمركوا اللي
+
+7
+00:00:30,880 --> 00:00:35,640
+بالتخصص بمعنى اللي بيشتغل في مجال المهن الصحية هذه
+
+8
+00:00:35,640 --> 00:00:39,640
+ال terminology لازم يكون حافظها للأبد و اللي طبعا
+
+9
+00:00:39,640 --> 00:00:43,280
+بيختار career تاني بعد ما يتخرج هو حر يحفظ أو ما
+
+10
+00:00:43,280 --> 00:00:47,490
+يحفظ هذا بيرجعلهال anatomical terminology هذه مهمة
+
+11
+00:00:47,490 --> 00:00:50,790
+لإنه هتنبني عليها كل المثقفات العملية و النظرية
+
+12
+00:00:50,790 --> 00:00:55,010
+اللي بدنا نفضها بعد هيك في مجال العلوم الصحية و
+
+13
+00:00:55,010 --> 00:00:58,710
+يفضل إنه احنا نكون حافظينها by heart لإن هي شغلات
+
+14
+00:00:58,710 --> 00:01:02,590
+صحيحة احنا اليوم هنكون عندنا دور في فهمهاوإدراكها
+
+15
+00:01:02,590 --> 00:01:07,410
+لكن هي بتنحفظ حفظ و هي عبارة عن كلمات متكررة في
+
+16
+00:01:07,410 --> 00:01:12,450
+سياق الدراسات ان شاء الله بالفصول القادمة كلها
+
+17
+00:01:12,450 --> 00:01:16,390
+بتسهل علينا عملية ال .. لنقول متابعة الدراسة بتسهل
+
+18
+00:01:16,390 --> 00:01:21,410
+علينا عملية القراءة و الاطلاع و الفهموإدراك حتى ما
+
+19
+00:01:21,410 --> 00:01:26,250
+نقيدش كل مرة نفسر المصطلحات هذه اسمها مصطلحات لازم
+
+20
+00:01:26,250 --> 00:01:29,950
+احنا نعرفها وأعتقد ان في منكم أخد مساقى المصطلحات
+
+21
+00:01:29,950 --> 00:01:34,050
+الطبية قد يكون مر عليه جزء منها الا ان في مجال
+
+22
+00:01:34,050 --> 00:01:37,930
+مساقى ال anatomy ما بنقدر الا ان احنا ناخدها ال
+
+23
+00:01:37,930 --> 00:01:40,350
+anatomical terminology اللى احنا نتحرف عليها أهم
+
+24
+00:01:40,350 --> 00:01:43,530
+اشي انه ان ال anatomical position هو اذا كان ان
+
+25
+00:01:43,530 --> 00:01:46,170
+شاء الله الكاميرا بتكشفني هو هذا الوضع انه بيوقف
+
+26
+00:01:46,170 --> 00:01:51,470
+الشخصبهذا الشكل ال face forward ال hands ال
+
+27
+00:01:51,470 --> 00:01:55,810
+balance forward و ال thumb لبرا و الأجرتين apart
+
+28
+00:01:55,810 --> 00:01:59,630
+طبعا واضحة بالصورة أن هذا اسمه anatomical position
+
+29
+00:01:59,630 --> 00:02:04,710
+يعني أي هو ال reference لكلمصطلح احنا بنتكلم بعدي
+
+30
+00:02:04,710 --> 00:02:09,270
+.. بنتكلم عنه في مجالاتنا المختلفة هو ال .. ال ..
+
+31
+00:02:09,270 --> 00:02:13,510
+ال .. ال position ال reference يعني لما بنتكلم عن
+
+32
+00:02:13,510 --> 00:02:17,410
+reflection انا بتكلم عن reflection من extended arm
+
+33
+00:02:17,410 --> 00:02:20,130
+بهذا الشكل نتكلم من supination و antipronation
+
+34
+00:02:20,130 --> 00:02:24,310
+نتكلم من هذا و كل المصالحات هذه هنمر عليها خلال
+
+35
+00:02:24,310 --> 00:02:28,450
+محاضرتنا طيب يعني هي عبارة عن إيش؟ هو position
+
+36
+00:02:30,190 --> 00:02:35,810
+الشخص بيكون فيه واقف upright ال feet على الأرض و
+
+37
+00:02:35,810 --> 00:02:39,390
+parallel و flat على ال floor زي ما احنا شايفين
+
+38
+00:02:39,390 --> 00:02:46,030
+بالمنظر اللي قدامنا هذا ال hip بيكون على مستوى ال
+
+39
+00:02:46,030 --> 00:02:51,770
+eyes بتطلع لقدام بتطلع الشخص فيه forwardطبعا كإنه
+
+40
+00:02:51,770 --> 00:02:55,990
+في حد واقف قدامك و بيتطلع عليه دايما بيكون to the
+
+41
+00:02:55,990 --> 00:03:00,370
+side الارض زى ما احنا شايفين ال side of the body و
+
+42
+00:03:00,370 --> 00:03:04,210
+بالطبع الفرنس forward و ال thumb ال lateral
+
+43
+00:03:04,210 --> 00:03:09,770
+positionطبعا في حاجة اسمها plans، إيش ال plans؟ هي
+
+44
+00:03:09,770 --> 00:03:16,310
+عبارة عن مقاطع للجسم بتسهل عملية تقسيم الجسم و
+
+45
+00:03:16,310 --> 00:03:20,010
+الحركة، لإن الحركة بتحصل في planet، في plan يعني
+
+46
+00:03:20,010 --> 00:03:24,460
+في عندنا imaginary surfaceمش بيعمل بيعمل cutting ل
+
+47
+00:03:24,460 --> 00:03:28,840
+ال body من خلال هذا ال cut اللي بيعمله بيخلينا
+
+48
+00:03:28,840 --> 00:03:32,240
+نقدر نفسر مثلا حركة ال flexion و ال extension
+
+49
+00:03:32,240 --> 00:03:35,700
+بيصير putsch plan مدان فى أننا plan و فى أننا حركة
+
+50
+00:03:35,700 --> 00:03:40,180
+يبقى فى أننا access ل الحركة plan is an imaginary
+
+51
+00:03:40,180 --> 00:03:46,710
+surface thatslices the body into specific sections
+
+52
+00:03:46,710 --> 00:03:51,970
+بيسموه لمقاطع سواء مقاطع طولية أو مقاطع عرضية طيب
+
+53
+00:03:51,970 --> 00:03:54,830
+إيش ال measure plans اللي إحنا بنتكلم عنهم؟ في
+
+54
+00:03:54,830 --> 00:03:57,670
+عندنا تلاتة measure هي ال coronary و ال transverse
+
+55
+00:03:57,670 --> 00:04:01,310
+و ال sagittal ال plan اللي كل الحركة اللي إحنا
+
+56
+00:04:01,310 --> 00:04:07,190
+بنتحركها بتدور في هدولة ال plans أو هذه الأسطح
+
+57
+00:04:07,190 --> 00:04:11,070
+اللي خليني نقول عنها التخيلية
+
+58
+00:04:13,190 --> 00:04:19,290
+طيب ال coronary plan هو عبارة عن plan بيقسم الجسم
+
+59
+00:04:19,290 --> 00:04:25,150
+بمقطع بهذا الشكلانقسام الجسم بهذا الشكل يعني في
+
+60
+00:04:25,150 --> 00:04:29,810
+عندنا anterior و في عندنا posterior surface يعني
+
+61
+00:04:29,810 --> 00:04:34,570
+في عندنا أمام و في عندنا خلال لأن ننظر للشخص هو
+
+62
+00:04:34,570 --> 00:04:39,350
+قدامنا نطلع عليه من قدام على ال anterior plan فهو
+
+63
+00:04:39,350 --> 00:04:43,310
+بيكون نظر عليه بال frontal plan و لو دهره فاحنا
+
+64
+00:04:43,310 --> 00:04:48,260
+بنتكلم عن ال back فهو ال posterior planأى مقطع فى
+
+65
+00:04:48,260 --> 00:04:52,900
+الجسم بهذا الشكل بهذا الشكل بيكون بيقطعوا نسميه فى
+
+66
+00:04:52,900 --> 00:04:58,820
+ال corner أو ال frontal قبلة أما ال transverse وهو
+
+67
+00:04:58,820 --> 00:05:05,560
+المقطع ال horizontal بيقطعوا نصين يا إما هو نصين
+
+68
+00:05:05,560 --> 00:05:09,600
+على الأكيد دائما لازم نص تحت و نص فوق بس بياخدوا
+
+69
+00:05:09,600 --> 00:05:16,370
+من مقاطع مختلفة طبعاإحنا لما بنقطع الجسم بهذا
+
+70
+00:05:16,370 --> 00:05:20,030
+الشكل معناه الحركات اللي بتصير حركات تقريبا بتكون
+
+71
+00:05:20,030 --> 00:05:23,230
+بهذا الشكل اللي هي الحركات الدورانية بهذا الشكل
+
+72
+00:05:23,230 --> 00:05:26,830
+أنا لما بشتغل بهذا الشكل أنا بشتغل ملامسة لإيش
+
+73
+00:05:26,830 --> 00:05:33,090
+ملامسة لل horizontal plan طبعا كل plan الحركة
+
+74
+00:05:33,090 --> 00:05:35,090
+بتصير فيه عن طريق axis
+
+75
+00:05:40,450 --> 00:05:44,970
+لما بنتكلم هيك انا لما بتكلم حركة بهذا الشكل بهذا
+
+76
+00:05:44,970 --> 00:05:47,670
+الشكل انا الحركة اللي قاعدة في ال horizon is plan
+
+77
+00:05:47,670 --> 00:05:52,190
+لازم يكون في عندي longitudinal axis بهذا الشكل هيك
+
+78
+00:05:52,190 --> 00:06:03,230
+و هيك ففي عندي axis بيمر في طول على طول الجسم انا
+
+79
+00:06:03,230 --> 00:06:09,900
+سجطة ال plan فهو بيقسم الجسم لجزئينطولي right and
+
+80
+00:06:09,900 --> 00:06:14,440
+left لو كان ماشي في مص الجسم فهو بيقسم الجسم
+
+81
+00:06:14,440 --> 00:06:17,220
+لجزئين متشابهين as a mirror
+
+82
+00:06:37,720 --> 00:06:41,480
+يكون يبقى في عندنا right side و في عندنا left side
+
+83
+00:06:41,480 --> 00:06:48,140
+نسميه median ابلان لما بيقسم الجسم لجزئين متساويين
+
+84
+00:06:48,140 --> 00:06:53,700
+left and right طبعا ممكن يصير في عندنا sections
+
+85
+00:06:53,700 --> 00:06:57,240
+يعني مش شرط انه يقسم الجسم من المنتصف ممكن يقسمه
+
+86
+00:06:57,240 --> 00:07:01,260
+من هنا من هنا من هنا من هنا ياخد مقاطع مختلفة لما
+
+87
+00:07:01,260 --> 00:07:05,400
+يكون في النصف فهو بيكون ال mid-sagittal ابلان
+
+88
+00:07:08,290 --> 00:07:13,010
+قطعوا لأجزاء مش ملاصفة فبنسمي ال بارا sagittal
+
+89
+00:07:13,010 --> 00:07:16,030
+يعني المهم أن في عندنا left side و في عندنا right
+
+90
+00:07:16,030 --> 00:07:21,430
+side ماكنتش بيكون oblique لما بيكون مش vertical ال
+
+91
+00:07:21,430 --> 00:07:25,870
+axis فبتصير في عندنا كانوا عامل an angle بنسمي
+
+92
+00:07:25,870 --> 00:07:32,730
+oblique plan هنا
+
+93
+00:07:32,730 --> 00:07:38,970
+طبعا احنا عرفنا ال two plansانا بتمنى منكوا كل
+
+94
+00:07:38,970 --> 00:07:45,720
+واحد يحاوليعمل الحركات و يقسم الحركات هذه اللى فى
+
+95
+00:07:45,720 --> 00:07:49,740
+الجسم على ال plans اللى موجودة هنتكلم عن ال
+
+96
+00:07:49,740 --> 00:07:52,460
+movement لما نتكلم عن ال musculoskeletal system بس
+
+97
+00:07:52,460 --> 00:07:56,220
+بدنا نذكر الكلام الكلام عن ال plan و ال accesses
+
+98
+00:07:56,220 --> 00:07:59,540
+عشان يوم ما بنحكي عن ال movement بدنا نرجعلها
+
+99
+00:07:59,540 --> 00:08:04,260
+نرجعلها بالتفصيل على أساس أنه نعرف كل حركة مثلا
+
+100
+00:08:04,260 --> 00:08:07,260
+حركة reflection of the elbow reflection and
+
+101
+00:08:07,260 --> 00:08:13,730
+extension بتكون فى which plan بتكون هيقاطع فبتكون
+
+102
+00:08:13,730 --> 00:08:16,750
+الحركة في ال digital plan لكن ال axis سبقها بيكون
+
+103
+00:08:16,750 --> 00:08:22,050
+بهذا الشكل في ال frontal plan ال axis هذا بده شرح
+
+104
+00:08:22,050 --> 00:08:25,850
+تفاصيل ان شاء الله هشرحه في وقته لما نوصل ل
+
+105
+00:08:25,850 --> 00:08:29,430
+movements of the body في ال musculoskeletal system
+
+106
+00:08:30,080 --> 00:08:33,580
+أما ال directional terms فإحنا لازم نعرف إيش تعني
+
+107
+00:08:33,580 --> 00:08:36,680
+كلمة superior، إيش تعني كلمة inferior، إيش تعني
+
+108
+00:08:36,680 --> 00:08:40,360
+كلمة lateral، إيش تعني كلمة medial، abduction،
+
+109
+00:08:40,360 --> 00:08:44,260
+adduction، كل الألفاظ هذه لنتعرف عليها من خلال
+
+110
+00:08:44,260 --> 00:08:48,840
+المصطلحات القادمة
+
+111
+00:08:48,840 --> 00:08:52,560
+المصطلحات دايما في عندنا opposition، دايما في
+
+112
+00:08:52,560 --> 00:08:56,760
+عندنا right، left، superior، inferior، abduction،
+
+113
+00:08:56,760 --> 00:09:03,100
+adduction، هنشوفهالو اتكلمنا عن ال .. ال
+
+114
+00:09:03,100 --> 00:09:08,060
+terminologies ال related to the .. the body فى
+
+115
+00:09:08,060 --> 00:09:10,980
+عندنا .. فى عندنا anterior side of the body و فى
+
+116
+00:09:10,980 --> 00:09:14,240
+عندنا ال posterior side of the body لو نطلع من
+
+117
+00:09:14,240 --> 00:09:17,520
+قدام فاحنا بنتكلم عن ال anterior كل هذا الجزء اسمه
+
+118
+00:09:17,520 --> 00:09:22,280
+anterior ال back فهو posterior part طبعا anterior
+
+119
+00:09:22,280 --> 00:09:27,520
+تعني in front or toward the front posterior to the
+
+120
+00:09:27,520 --> 00:09:34,840
+backالدورسل at the side of the human body اما ال
+
+121
+00:09:34,840 --> 00:09:39,280
+ventral ال back اسمها دورسل ها بنسميها the dorsum
+
+122
+00:09:39,280 --> 00:09:42,580
+of the foot هنا ال ventral of the foot او ال
+
+123
+00:09:42,580 --> 00:09:46,780
+palmar surface of the hand sorry ال ventral at the
+
+124
+00:09:46,780 --> 00:09:51,500
+bellyside of the .. يعني ناحية البطل بنسميه
+
+125
+00:09:51,500 --> 00:09:56,620
+ventral ناحية الدهر بنسميه dorsal هو نفسه الكلام
+
+126
+00:09:56,620 --> 00:10:01,620
+عن anterior و الكلام عن posterior يبقى anterior و
+
+127
+00:10:01,620 --> 00:10:06,280
+ventral كلمات مترادفة posterior و dorsal كلمات
+
+128
+00:10:06,280 --> 00:10:11,120
+أيضا مترادفة لكن anterior عكسها posterior و dorsal
+
+129
+00:10:11,120 --> 00:10:16,580
+عكسها ventral أما عن ال ..
+
+130
+00:10:19,600 --> 00:10:24,800
+الـ Terminology الخاصة بالقرب من الرأس أو القرب من
+
+131
+00:10:24,800 --> 00:10:29,260
+الذيل أو من الفوتو كل ما اقتربنا من الرأس فاحنا
+
+132
+00:10:29,260 --> 00:10:34,360
+بنكون superior إلى أعلى طلع إلى أعلى means above
+
+133
+00:10:34,360 --> 00:10:40,060
+towards the head أما ال inferior مازل تحت فهو رايح
+
+134
+00:10:40,060 --> 00:10:47,840
+towards the feetcodal و cranial ال cranial هي دي
+
+135
+00:10:47,840 --> 00:10:50,840
+ال skull اسمها cranial في terminology ال skull
+
+136
+00:10:50,840 --> 00:10:55,340
+means cranial طب كل ما اقتربنا إلى ال cranial فهو
+
+137
+00:10:55,340 --> 00:10:59,220
+بنسميه cranial أما codal بنروح ناحية الذيل بتعرفوا
+
+138
+00:10:59,220 --> 00:11:04,520
+أنه حتى في الإنسان في عظمة الذيل اللي هي الأصوص
+
+139
+00:11:04,520 --> 00:11:08,630
+احنا بنسميها أو ال coaxes كل ما اقتربنا منهذه
+
+140
+00:11:08,630 --> 00:11:12,810
+المنطقة فبنكون احنا codal اما لو طلعنا فوق طبعا
+
+141
+00:11:12,810 --> 00:11:15,990
+terminology نحتاج لمحادرات كاملة في مجال
+
+142
+00:11:15,990 --> 00:11:20,570
+terminology هتاخدوها ان شاء الله في الفصل القادم
+
+143
+00:11:20,570 --> 00:11:24,110
+او اذا كنتوا اخدوها في الفصل الاول فcodal بنروح
+
+144
+00:11:24,110 --> 00:11:29,230
+ناحيت ال tail ال cranial بنروح أضاف superior
+
+145
+00:11:29,230 --> 00:11:32,390
+medial
+
+146
+00:11:34,060 --> 00:11:41,850
+كل ما اقتربنا للمنتصف فاحنا بنروح medianبنروح
+
+147
+00:11:41,850 --> 00:11:46,010
+lateral يبقى الاقتراب من ال midline means medial
+
+148
+00:11:46,010 --> 00:11:50,250
+الاقتراب من ال .. البتعاد عن ال midline means
+
+149
+00:11:50,250 --> 00:11:54,430
+lateral في حاجة اسمها deep and superficial كل ما
+
+150
+00:11:54,430 --> 00:11:58,990
+طلعنا على السطح فاحنا بنكون superficial كنا نزلنا
+
+151
+00:11:58,990 --> 00:12:04,010
+deep بنكون احنا .. بنكون deep يعني بنكون ..
+
+152
+00:12:04,010 --> 00:12:10,100
+بنتنقلب من الأعماق طيب هنابكتير من الألفاظ هذه
+
+153
+00:12:10,100 --> 00:12:13,980
+بتحتاج لأمثلة لو اتكلمنا ال skin هو superficial
+
+154
+00:12:13,980 --> 00:12:19,060
+لكن ال muscle more deep ال bone deep أكتر لكن ال
+
+155
+00:12:19,060 --> 00:12:23,060
+muscle superficial than ال bone ال skin أكتر
+
+156
+00:12:23,060 --> 00:12:27,560
+superficial فهذه الألفاظ احنا بنستخدمها أحيانا
+
+157
+00:12:27,560 --> 00:12:31,580
+للمقارنة يعني اللي بيكون في اللحظة هذهفي بعض
+
+158
+00:12:31,580 --> 00:12:36,440
+المصطلحات أو لما بنوصف بعض الأنسجة اللي موجودة في
+
+159
+00:12:36,440 --> 00:12:40,740
+الجسم ممكن تكون في لحظة هي deep و لحظة تكون
+
+160
+00:12:40,740 --> 00:12:43,920
+superficial يعني بتكون هي deep in relation to
+
+161
+00:12:43,920 --> 00:12:47,740
+other tissue زي ال bone، deep in relation to the
+
+162
+00:12:47,740 --> 00:12:50,760
+muscle ال muscle deeper than the skin like skin
+
+163
+00:12:50,760 --> 00:12:55,060
+superficial ال muscle superficial than bone وهدي
+
+164
+00:12:55,060 --> 00:12:58,500
+.. هذا اللي بيلزمنا احنا لما نتعرف على هذه ال
+
+165
+00:12:58,500 --> 00:13:03,140
+terminologyوكمان دائما احنا لو طلعنا على ال upper
+
+166
+00:13:03,140 --> 00:13:07,220
+limb، فيها proximal و فيها distal، صحيح؟ طيب، إيش
+
+167
+00:13:07,220 --> 00:13:10,380
+يعني proximal قريب من ال trunk؟ إيش يعني distal
+
+168
+00:13:10,380 --> 00:13:14,160
+بعيدة عن ال trunk؟ ال hand is distal to the wrist,
+
+169
+00:13:14,640 --> 00:13:19,240
+distal to the elbow, distal to the shoulder، okay،
+
+170
+00:13:19,240 --> 00:13:20,660
+لكن ال shoulder proximal
+
+171
+00:13:22,940 --> 00:13:26,460
+الإلبو لما بدي أقارنه بال shoulder فهو distal to
+
+172
+00:13:26,460 --> 00:13:29,120
+the shoulder لكن لو بدي أقارنه بال rest فهو
+
+173
+00:13:29,120 --> 00:13:31,040
+proximal to the shoulder
+
+174
+00:13:53,030 --> 00:13:59,350
+ان شاء الله طبعا في ال anatomical terms في كتير من
+
+175
+00:13:59,350 --> 00:14:05,270
+المصطلحات اللي هي ممكن تكون كلمات غرقية او لاتينية
+
+176
+00:14:05,270 --> 00:14:11,950
+او يونانية فهذه الها مرادفات الها مرادفات وين؟ في
+
+177
+00:14:11,950 --> 00:14:18,330
+اللغة الإنقليزية فلو كنا ال cephalic means head ال
+
+178
+00:14:18,330 --> 00:14:24,750
+frontal بتسوي ال fourhead نيزل يعني nose ال orbit
+
+179
+00:14:24,750 --> 00:14:31,130
+كلمة كتير مختلفة means eyes orbital يبقى إشي
+
+180
+00:14:31,130 --> 00:14:36,550
+حوالين ال eyes نيزل فإشي حوالين ال nose
+
+181
+00:14:43,220 --> 00:14:49,280
+Poxal cheek مثلا العضلات اسمها Poxy عادة فاسمها
+
+182
+00:14:49,280 --> 00:14:54,140
+Poxal ال oral منطقة ال mouth ال mouth means oral
+
+183
+00:14:54,140 --> 00:14:57,760
+لما اتكلم عن oral oral cavity يبقى منطقة ال cavity
+
+184
+00:14:57,760 --> 00:15:04,120
+اللي موجودة في ال mouth cervical neck اتكلم عن اي
+
+185
+00:15:04,120 --> 00:15:07,400
+اشي cervical بين cervical, spondylosis, cervical
+
+186
+00:15:07,400 --> 00:15:12,800
+whatever احنا اللي بنتكلم عنه فهو means neckmental
+
+187
+00:15:12,800 --> 00:15:18,240
+chin دقن acromial هنا ال shoulder ليش لأن في عضلة
+
+188
+00:15:18,240 --> 00:15:22,240
+هنتعرف علي اسمها ال acromion هنا في رأس الكتف فهو
+
+189
+00:15:22,240 --> 00:15:26,820
+عشان يكي بيرمزله ال shoulder بال acromial sternal
+
+190
+00:15:26,820 --> 00:15:30,840
+منطقة ال breast bone اللي هي ال sternum عظمة اللي
+
+191
+00:15:30,840 --> 00:15:36,100
+بنسميها القص اكسل لرئيه ال armpit اللي هو احنا
+
+192
+00:15:36,100 --> 00:15:41,670
+بنسميه ال ابتexellar crutches لما بيمسك الشخص على
+
+193
+00:15:41,670 --> 00:15:46,270
+الككيز اللي تحت القبد بيسميه exellar لرمزها يعني
+
+194
+00:15:46,270 --> 00:15:51,890
+بنوصفها بهذا الشكل thoracic means schist منطقة ال
+
+195
+00:15:51,890 --> 00:15:56,370
+thorax كلها هي منطقات ال schist mammary ماماري
+
+196
+00:15:56,370 --> 00:16:01,990
+اللي هي ال breasts brachial في هنا عضمة اسمها
+
+197
+00:16:01,990 --> 00:16:05,590
+brachial bone فعشان هي بتسمى منطقة القارب هذه
+
+198
+00:16:05,590 --> 00:16:07,190
+اسمها brachial
+
+199
+00:16:11,580 --> 00:16:15,940
+Anticubital منطقة إيش؟ ال forward part أو ال
+
+200
+00:16:15,940 --> 00:16:22,360
+anterior part of the elbow الolecranon،
+
+201
+00:16:22,360 --> 00:16:25,320
+في عضمة هنا اسمها olecranon، فبنسميها olecranon،
+
+202
+00:16:25,320 --> 00:16:30,140
+هي منطقة راس ال elbow joint أو ال back of the
+
+203
+00:16:30,140 --> 00:16:35,330
+elbow jointالـ Antibracial اللي هي الـ forearm،
+
+204
+00:16:35,330 --> 00:16:42,130
+هذه العضمة اسمها forearm، Popliteal هي posterior
+
+205
+00:16:42,130 --> 00:16:46,110
+of the knee، منطقة الـ back of the knee فهي اسمها
+
+206
+00:16:46,110 --> 00:16:50,730
+الـ Popliteal area، هنشوف فائدها على ال diagrams
+
+207
+00:16:51,910 --> 00:16:56,130
+sural ال calf في عضمة اسمها عضلة اسمها ال calf
+
+208
+00:16:56,130 --> 00:17:00,410
+muscle، carpel منطقة ال wrists يعني بيسميها carpel
+
+209
+00:17:00,410 --> 00:17:03,210
+لإن في عندنا تمانية carpel bones اتعرف عليهم في
+
+210
+00:17:03,210 --> 00:17:07,390
+الانهاتف من بكرا و نحفظهم اسمها carpel bones فهي
+
+211
+00:17:07,390 --> 00:17:11,870
+منطقة المنطقةالـ Pollocks بيسميه Pollicis اللي هو
+
+212
+00:17:11,870 --> 00:17:15,530
+منطقة الثمب، كل العضلات اللي في منطقة الثمب، الثمب
+
+213
+00:17:15,530 --> 00:17:19,810
+بيسميها Pollicis ال digital هي ال fingers عبارة عن
+
+214
+00:17:19,810 --> 00:17:24,170
+الأصابع، أصابع الأديان أو أصابع الرجلين ال pubic
+
+215
+00:17:24,170 --> 00:17:29,250
+منطقة الجينيتاليا، منطقة الأعضاء التناثلية فبتسمى
+
+216
+00:17:29,250 --> 00:17:32,310
+pubic، نتيجة ل .. ليش اتسمت هيك؟ لإن في عضمة في
+
+217
+00:17:32,310 --> 00:17:37,110
+هذا المكان اسمها pupisالباتلر في الصابونة الرجل
+
+218
+00:17:37,110 --> 00:17:40,290
+اسمها باتلر فأي شي related لهذا المنطقة بتسمي
+
+219
+00:17:40,290 --> 00:17:44,230
+باتلر اللي هي anterior part of the knee Plural
+
+220
+00:17:44,230 --> 00:17:49,090
+منطقة ال leg تارسل منطقة ال ankles لإن في انا
+
+221
+00:17:49,090 --> 00:17:53,770
+تارسل bones تارسل وميتا تارسل التارسل bone اللي هي
+
+222
+00:17:53,770 --> 00:17:58,170
+عضمة ال .. عضمة ال heel التالس والكلكانيا بتسمى
+
+223
+00:17:58,170 --> 00:18:03,060
+التارسلأما ال helix فهو ال big toes العضلات اللي
+
+224
+00:18:03,060 --> 00:18:06,300
+هناك بيسميها helices flexor helices extensor
+
+225
+00:18:06,300 --> 00:18:11,740
+helices فهي منطقة ال big two في ال food ال
+
+226
+00:18:11,740 --> 00:18:16,280
+occipital ال back أو ال base of the skull بيسميها
+
+227
+00:18:16,280 --> 00:18:21,780
+occipital أو occipotال vertebral means spines، ال
+
+228
+00:18:21,780 --> 00:18:26,160
+vertebra نفسها مكونات العمود الفقري بتكون من فقرات
+
+229
+00:18:26,160 --> 00:18:32,540
+متراسة فهو اسمها vertebral أو spinal scapular من
+
+230
+00:18:32,540 --> 00:18:37,080
+منطقة ال shoulder blade، في هنا قدمة لسكابيولا
+
+231
+00:18:37,080 --> 00:18:43,200
+اللي هي لوحة الكتف اسمها scapulaالـ Dorsum طيب و
+
+232
+00:18:43,200 --> 00:18:46,280
+اتعرفنا عليه قولنا ال pack ال Dorsum of the hand و
+
+233
+00:18:46,280 --> 00:18:50,100
+ال Dorsum of the foot اللي هي المنطقة العليا من
+
+234
+00:18:50,100 --> 00:18:52,160
+القدم
+
+235
+00:18:56,210 --> 00:19:00,830
+loin الـ sacral المنطقة الـ sacrum اللي هي موجودة
+
+236
+00:19:00,830 --> 00:19:04,910
+between the hips والبرنيال المنطقة اللي موجودة في
+
+237
+00:19:04,910 --> 00:19:09,810
+منطقة ال genitalia و ال femoral means thigh لأنه
+
+238
+00:19:09,810 --> 00:19:14,150
+في عضمة اسمها ال femorous او ال femur فهي مسمية
+
+239
+00:19:14,150 --> 00:19:19,790
+femoral الكلكانية المنطقة عضمة ال ال heel او الكعب
+
+240
+00:19:19,790 --> 00:19:26,110
+plantar اللي هي السولplantar surface of the heart
+
+241
+00:19:26,110 --> 00:19:30,010
+بعلمر surface هنا بنسميه لكن الفوت بنسميه plantar
+
+242
+00:19:30,010 --> 00:19:33,470
+surface المنطقة اللي ملاسقة للأرض و احنا واقفين
+
+243
+00:19:33,470 --> 00:19:42,600
+فاسمها plantar ال soul طبعا هذاتوضيح كل الأشياء
+
+244
+00:19:42,600 --> 00:19:47,240
+اللى احنا اتكلمنا عنها قبل شوية بالرسم مفيكم
+
+245
+00:19:47,240 --> 00:19:51,820
+تتبعوه سواء كان ال forehead ال frontal ال orbital
+
+246
+00:19:51,820 --> 00:19:56,160
+منطقة ال eye ال pixel الشيك ال mental chin ال
+
+247
+00:19:56,160 --> 00:20:00,640
+nasal ال oral cavity ال cervical كل ال
+
+248
+00:20:03,150 --> 00:20:06,730
+ال terminology اللي احنا اتكلمنا عنها قبل شوية فهي
+
+249
+00:20:06,730 --> 00:20:11,590
+مفصلة على هذا ال diagram نقدر نقول هذا ال diagram
+
+250
+00:20:11,590 --> 00:20:19,230
+هو frontalview anterior view لأنه بيعطيني كل الجزء
+
+251
+00:20:19,230 --> 00:20:24,730
+الأمامي من الجسم مفصل طبعا كتير احنا لما بنيجي
+
+252
+00:20:24,730 --> 00:20:27,710
+نعمل ال assessment أكرا نطلع على الشخص بنحتاج فيه
+
+253
+00:20:27,710 --> 00:20:30,730
+بعض الأشياء بنشوفها في ال anterior view وفيه أشياء
+
+254
+00:20:30,730 --> 00:20:33,990
+ليه ممكن نستوضحها من ال anterior view لازم نروح
+
+255
+00:20:33,990 --> 00:20:37,410
+للبستير وفي بعض الأشياء و الحركات لازم نشوفها من
+
+256
+00:20:37,410 --> 00:20:42,080
+ال lateral view وهذا كلهإن شاء الله مع التقدم
+
+257
+00:20:42,080 --> 00:20:48,780
+خلّينا في المساقات هتتعرفوا عليه لاحقا، شايفين؟
+
+258
+00:20:48,780 --> 00:20:51,320
+اللي هتضطرين عشان نقول Oxypetal bone أو الـ
+
+259
+00:20:51,320 --> 00:20:56,580
+أوكسبتالبون لازم نطلع عليها من posterior viewلازم
+
+260
+00:20:56,580 --> 00:21:01,180
+نطلع عليها من الخلف وهذه طبعا كل الأشياء اللي ممكن
+
+261
+00:21:01,180 --> 00:21:07,260
+نشوفها في جسم الإنسان من ال posterior view زي ال
+
+262
+00:21:07,260 --> 00:21:11,500
+occipital bone ال crania من ال posterior part
+
+263
+00:21:11,800 --> 00:21:15,800
+الـOlecranium of the elbow، المنطقة الـpupilial
+
+264
+00:21:15,800 --> 00:21:20,480
+part of the foot، هي الـleg، الـcalcaneus، لازم
+
+265
+00:21:20,480 --> 00:21:23,400
+نشوفها من الأمام، لازم نشوفها من الأعلى، حتى
+
+266
+00:21:23,400 --> 00:21:27,120
+بتلاقوا أن الصور هذه كلها مروسة بـstereo view
+
+267
+00:21:27,120 --> 00:21:30,660
+وanterior view، عشان نعرف إحنا من أنهي view، ممكن
+
+268
+00:21:30,660 --> 00:21:34,770
+نتطلع أو نشوف الأشياء هذه، الأشياء كتير مهمةحتى
+
+269
+00:21:34,770 --> 00:21:40,770
+احنا في خلال ان شاء الله اختبارنا لل .. للمادة و
+
+270
+00:21:40,770 --> 00:21:44,870
+ماذا تحصلكم المادة هتكون كتير أسئلة في المجال هذا
+
+271
+00:21:44,870 --> 00:21:48,490
+حتى تكونوا عندكوا قدرة معرفة الأشياء أنتي لما
+
+272
+00:21:48,490 --> 00:21:51,110
+بنطلع عليها بنطلع عليها من which view من ال
+
+273
+00:21:51,110 --> 00:21:55,800
+anterior ولا من ال posteriorطبعا لو قسمنا ال body
+
+274
+00:21:55,800 --> 00:22:01,060
+احنا بنقسم ال body لجزئين عندنا ال axial portion و
+
+275
+00:22:01,060 --> 00:22:06,620
+عندنا ال perpendicular ال axial هو الجسم عبارة عن
+
+276
+00:22:06,620 --> 00:22:13,090
+ال headمع ال neck, chest بيخلص من هنا بنسمي احنا
+
+277
+00:22:13,090 --> 00:22:17,790
+ال trunk يبقى ال head and neck and ال trunk أما ال
+
+278
+00:22:17,790 --> 00:22:22,110
+perpendicular ف means lower limb و ال upper limb
+
+279
+00:22:22,110 --> 00:22:26,110
+يعني ال arms و ال legs يعني الإيدين و الرجلين احنا
+
+280
+00:22:26,110 --> 00:22:29,980
+بالعرب بيقولهالكن ال upper limb كاملة و ال lower
+
+281
+00:22:29,980 --> 00:22:34,660
+limb كاملة عشان كل واحد من هذه الأشياء المكونات
+
+282
+00:22:34,660 --> 00:22:38,080
+تبع جسم الإنسان اللي أعطتها هي أو المنظر لجسم
+
+283
+00:22:38,080 --> 00:22:43,320
+الإنسان كل واحد منهم و وظيفته الخاصة اللي خلق من
+
+284
+00:22:43,320 --> 00:22:47,080
+.. من أجلها طبعا في ال axial portion في عنا
+
+285
+00:22:47,080 --> 00:22:51,820
+cavities هذه ال cavities لازم احنا نتعرف عليها و
+
+286
+00:22:51,820 --> 00:22:56,400
+نكون وعين لإلها في عنا ال cranial cavityلأن هذه
+
+287
+00:22:56,400 --> 00:23:00,740
+العيون الجمجمة اللي بتحتوي على عضو مهم جدا من
+
+288
+00:23:00,740 --> 00:23:05,320
+أعضاء الجسم اللي هو ال brain، ال brain عشان هيك ال
+
+289
+00:23:05,320 --> 00:23:08,800
+brain محط بالأذام، يعني وظيفة الأذام هنجي في مساقل
+
+290
+00:23:08,800 --> 00:23:12,820
+.. لما نجي نوصل ل ال skeletal system إيش وظيفته؟
+
+291
+00:23:12,820 --> 00:23:20,310
+وظيفته إنهيحافظ على الأحشاء أو الحشوات اللي موجودة
+
+292
+00:23:20,310 --> 00:23:23,490
+فيه، يعني ال cranium بتحافظ على ال brain ال
+
+293
+00:23:23,490 --> 00:23:27,090
+vertebral canal هذه اللي موجودة في ال vertebral
+
+294
+00:23:27,090 --> 00:23:31,350
+column بتحافظ على ال spinal cordأما هذه الأشياء
+
+295
+00:23:31,350 --> 00:23:34,630
+اللي بنشوفها احنا من الخلق أما من الأمام إيش بيكون
+
+296
+00:23:34,630 --> 00:23:37,250
+فيها ثرس ال cavity ثرس ال cavity اللي بتطلع من
+
+297
+00:23:37,250 --> 00:23:40,530
+الأمام بتطلع أنا بتخيل لو شلط العضم هذا وفتحته
+
+298
+00:23:40,530 --> 00:23:43,530
+بهذا الشكل إيش بيكون جوا؟ بيكون ال lungs
+
+299
+00:23:43,530 --> 00:23:47,650
+المديستينة الthymus ال heart ال oesophagus
+
+300
+00:23:47,650 --> 00:23:52,830
+التراكيا كل هذه cavities موجودة في ال
+
+301
+00:23:55,420 --> 00:23:59,420
+الـ cavity اللى موجودة بتاعة ال chest cavity أما
+
+302
+00:23:59,420 --> 00:24:03,340
+ال abdominal pelvic فطبعا احنا بطلع على منطقة ال
+
+303
+00:24:03,340 --> 00:24:06,500
+abdominal cavity بكون فيه لنا ال stomach و ال
+
+304
+00:24:06,500 --> 00:24:09,960
+liver و سلين و جوا ال brother ال intestine سواء
+
+305
+00:24:09,960 --> 00:24:15,040
+large أو small intestine يعني كل اللى بنسميهم احنا
+
+306
+00:24:15,040 --> 00:24:20,980
+الأحشاءبال .. بالعربي، المعدة و الكبد و الطحال و
+
+307
+00:24:20,980 --> 00:24:25,780
+الأمعاء الغليظة و الأمعاء الرفيعة و المرارة و كل
+
+308
+00:24:25,780 --> 00:24:30,080
+الأشياء هذه اللي بتكون موجودة، حتى الواحد لما بيتج
+
+309
+00:24:30,080 --> 00:24:34,100
+عملية، لما بيتج عملية في الأحجاق، بيروحوا بيفتحوا
+
+310
+00:24:34,100 --> 00:24:37,440
+بطنهأما احتاج عملية في الرأس بيفتحوا ال cranium
+
+311
+00:24:37,440 --> 00:24:40,220
+احتاج عملية مثلا في ال spinal cord بيفتحوا ال
+
+312
+00:24:40,220 --> 00:24:43,300
+spinal فحتى ال position اللى بنوضع فيه المريض
+
+313
+00:24:43,300 --> 00:24:49,800
+هيختلف طبعا هيروح يفوت ل ال cranium من الخلفأو لـ
+
+314
+00:24:49,800 --> 00:24:53,240
+Spinal cord بتنام المريض على بطنه عشان يعرف يشتغل
+
+315
+00:24:53,240 --> 00:24:56,280
+أما هنا لو بنعمل abdominal surgery بتنام المريض
+
+316
+00:24:56,280 --> 00:24:59,480
+على دهره و احنا بنبقى عارفين حتى ال positions هذه
+
+317
+00:24:59,480 --> 00:25:04,460
+كيف بدوا يتعامل معها الأخصائين أو الجرحين في هذا
+
+318
+00:25:04,460 --> 00:25:07,720
+لما بدوا يفوت لانهي cavity من هذه ال cavities من
+
+319
+00:25:07,720 --> 00:25:12,600
+انهي position هو بده يفوت منطقة البلفد cavity اللي
+
+320
+00:25:12,600 --> 00:25:16,600
+هي منطقة الحوت بتحتوي على ال urinaryالـ Bladder
+
+321
+00:25:16,600 --> 00:25:21,720
+اللي هي المثانا و كل ال internal reproductive for
+
+322
+00:25:21,720 --> 00:25:26,640
+male and female و طبعا هذا كله هنتكلم عليه في ال
+
+323
+00:25:26,640 --> 00:25:31,620
+musculoskeletal system طبعا ال diaphragm هي عبارة
+
+324
+00:25:31,620 --> 00:25:37,680
+عن عضلةتقسم ال cavities اللي موجودة جوا ل upper
+
+325
+00:25:37,680 --> 00:25:42,240
+and lower دي افراج هي عضلة التنفس ال main
+
+326
+00:25:42,240 --> 00:25:47,520
+respiratory muscle اللي احنا لما بناخدInspiration
+
+327
+00:25:47,520 --> 00:25:51,280
+هي بصيرها contraction بتوسع ال thoracic cavity هذه
+
+328
+00:25:51,280 --> 00:25:55,200
+بتخلي الهوى يدخل، لكن هذه العضلة إيش وظفتها؟ بتعمل
+
+329
+00:25:55,200 --> 00:25:58,380
+.. بتلعب دور أساسي في عملية التنفس وكمان بتلعب دور
+
+330
+00:25:58,380 --> 00:26:01,880
+أساسي بالفصل بين ال cavities اللي موجودة في الجسم
+
+331
+00:26:01,880 --> 00:26:07,260
+ال abdominal cavity و thoracic cavityطبعا ال
+
+332
+00:26:07,260 --> 00:26:10,540
+kidney و ال adrenal gland و ال pancreas و ال
+
+333
+00:26:10,540 --> 00:26:15,640
+ureters are behind the abdominal pelvic cavity هى
+
+334
+00:26:15,640 --> 00:26:24,340
+موجودة فى البطن بس شوية لورا طبعا هذا رسم توضيحى ل
+
+335
+00:26:24,340 --> 00:26:30,480
+ال ventral cavity فى أن هي ال thoracicو ال
+
+336
+00:26:30,480 --> 00:26:33,380
+diaphragm اللى هى العضله هادى اللى بتقسم بين ال
+
+337
+00:26:33,380 --> 00:26:37,660
+abdomen and chest و هاد ال abdomen هاد ال cavity و
+
+338
+00:26:37,660 --> 00:26:41,380
+هاد ال pelvic cavity بتكون كتير lower فى منطقه
+
+339
+00:26:41,380 --> 00:26:46,390
+الحوض فبسموها abdomen و pelvic cavityهنا من ال
+
+340
+00:26:46,390 --> 00:26:49,050
+anterior view هنا اللى موجودة فى ال anterior side
+
+341
+00:26:49,050 --> 00:26:52,370
+بتيجى عندنا الحد و العلامة تبعتنا للبستيرور فى
+
+342
+00:26:52,370 --> 00:26:55,830
+عندنا ال cranial cavity و فى عندنا ال vertebral
+
+343
+00:26:55,830 --> 00:26:59,850
+cavity اللى هى بتحتوي على ال spinal cord و فوق
+
+344
+00:26:59,850 --> 00:27:02,830
+بتحتوي على ال brain
+
+345
+00:27:08,400 --> 00:27:12,540
+وها دراسة توضيحي أكتر برضه بيوضحلنا كل الأشياء
+
+346
+00:27:12,540 --> 00:27:16,140
+اللي احنا اتكلمنا عليها قبل شوية سواء اللي في
+
+347
+00:27:16,140 --> 00:27:20,740
+عندنا طبعا نتكلم على ال chest cavity فيها تحتوي
+
+348
+00:27:20,740 --> 00:27:26,680
+على ال right و left lungs ال heart المديستينم اللي
+
+349
+00:27:26,680 --> 00:27:31,580
+في عندنا ال plural cavity في عندنا ال diaphragm
+
+350
+00:27:31,580 --> 00:27:35,880
+اللي هو شايفين تفصل هذه المنطقة عن تفصل ال chest
+
+351
+00:27:35,880 --> 00:27:36,900
+عن ال abdomen
+
+352
+00:27:44,820 --> 00:27:49,480
+هنروح على ال membranes اللي موجودة جوا، طبعا هي ال
+
+353
+00:27:49,480 --> 00:27:52,700
+membranes هي عبارة عن الأغشية اللي بتحيط في
+
+354
+00:27:52,700 --> 00:27:56,560
+الأنسجة، في عندنا نوعين من ال membranes ال
+
+355
+00:27:56,560 --> 00:28:00,020
+visceral و في ال parietal، ال visceral هو اللي
+
+356
+00:28:00,020 --> 00:28:05,520
+بحيط الأحشاء نفسها، أما ال parietal فهي بتحيط ال
+
+357
+00:28:05,520 --> 00:28:12,130
+body cavity نفسها طبعاال .. هدول الأنسجة ..
+
+358
+00:28:12,130 --> 00:28:15,810
+الأنسجة في عندنا طبقتين من الأنسجة وما بين هدول
+
+359
+00:28:15,810 --> 00:28:19,110
+الطبقتين في عندنا حاجة اسمها Cirrus .. Cirrus
+
+360
+00:28:19,110 --> 00:28:23,750
+Fluid Cirrus Fluid هذا إيش وظيفته؟ وظيفته إنه يعمل
+
+361
+00:28:23,750 --> 00:28:29,910
+lubricants يمنع الاحتكاك يرتب ال .. المكان حتى
+
+362
+00:28:29,910 --> 00:28:34,170
+يساعد على .. فإحنا إذا بناخد نفس بتتوسع ال chest
+
+363
+00:28:34,170 --> 00:28:40,710
+صحيح؟بتحاط ال lungs في ال plural membrane بتكون
+
+364
+00:28:40,710 --> 00:28:44,430
+على أساس إنه ما بين ال plural و ال parietal بيكون
+
+365
+00:28:44,430 --> 00:28:50,770
+في عندنا ال serous effluent يبقى soft، thin
+
+366
+00:28:51,270 --> 00:28:56,110
+Playable layers of tissue that either يأما cover
+
+367
+00:28:56,110 --> 00:28:59,890
+ال vital أو ال visceral organ اللي هي موجودة في
+
+368
+00:28:59,890 --> 00:29:03,950
+الداخل اللي هي الحشوية أو الأحشاء ال parietal اللي
+
+369
+00:29:03,950 --> 00:29:08,430
+هي الجسدية اللي بتكون لبرا lines او body cavity هي
+
+370
+00:29:08,430 --> 00:29:11,910
+ال parietal membrane
+
+371
+00:29:13,420 --> 00:29:17,600
+طبعا هان هيوضح لنا كل membrane من الموجودين سواء
+
+372
+00:29:17,600 --> 00:29:23,060
+في ال lungs، سواء في ال heart، سواء في ال viscera،
+
+373
+00:29:23,060 --> 00:29:26,340
+إيش هو؟ there are specific names for membranes
+
+374
+00:29:26,340 --> 00:29:30,360
+around ال heart و ال lungs و ال abdominal organs،
+
+375
+00:29:30,360 --> 00:29:34,800
+في عناالـ Serious membrane of the lungs كلنا سمعنا
+
+376
+00:29:34,800 --> 00:29:39,240
+يوما ما عن البلورة، في عندنا الviscera البلورة
+
+377
+00:29:39,240 --> 00:29:44,640
+اللى محيط باللغة نفسها فاسمها viscera البلورة أما
+
+378
+00:29:44,640 --> 00:29:48,340
+ال lines ده cavity in which the lung located يعني
+
+379
+00:29:48,340 --> 00:29:52,730
+عند ال chest cage نفسه فاسمها parietal بلورةin
+
+380
+00:29:52,730 --> 00:29:57,210
+between فى عندنا هذا ال fluid اللى فى ال Cerase
+
+381
+00:29:57,210 --> 00:30:01,530
+Fluid او الغشاء او السائل المصلي اللى بيكون بيساعد
+
+382
+00:30:01,530 --> 00:30:06,970
+على ال lupricants للمكان يعنى احنا فى عندنا بلورة
+
+383
+00:30:06,970 --> 00:30:11,810
+هذا البلورة الجزء المحيط بال lung اسمه فزيرالبلورة
+
+384
+00:30:11,810 --> 00:30:17,870
+اما الجزء الملاسق لعضمات ال ribs و عضمة القصفة فهى
+
+385
+00:30:17,870 --> 00:30:23,000
+اسمها Parietal Blura الجزء الخارجىبيكون، يعني
+
+386
+00:30:23,000 --> 00:30:26,860
+الداخل اللي حوالين الأحشاء بيكون اسمه visceral أما
+
+387
+00:30:26,860 --> 00:30:31,040
+الخارج بيكون هو parietal، لكن إحنا إنه بنشوفهم
+
+388
+00:30:31,040 --> 00:30:35,810
+كإنهم عندنا الرأس نضيح يورجينا إيه يعني؟أما الـ
+
+389
+00:30:35,810 --> 00:30:40,310
+heart في عيننا visceral بريكارديام هو الملاصق that
+
+390
+00:30:40,310 --> 00:30:43,670
+membrane lines the cavity in which the heart is
+
+391
+00:30:43,670 --> 00:30:47,870
+located اسمه البرايتل، الvisceral بيكون ملاصق لل
+
+392
+00:30:47,870 --> 00:30:53,710
+heart أما البرايتل فهو ملاصق للجزء أو المكان اللي
+
+393
+00:30:53,710 --> 00:31:00,090
+موجود في ال heart وطبعا in between بيكون ال serous
+
+394
+00:31:00,090 --> 00:31:06,070
+fluidهدولة كتير مهم إحنا نقرا، يبقى فيه عندنا
+
+395
+00:31:06,070 --> 00:31:08,850
+pericardium visceral وفيه عندنا pericardium
+
+396
+00:31:08,850 --> 00:31:12,090
+parietal و in between في عندنا حاجة اسمها
+
+397
+00:31:12,090 --> 00:31:16,050
+pericardial cavity، هذه موجودة بين ال visceral و
+
+398
+00:31:16,050 --> 00:31:18,610
+ال parietal membrane اللي هو إحنا بنسميهم ال
+
+399
+00:31:18,610 --> 00:31:22,530
+pericardium كلمة بني معناها محيط، يعني الغلاف
+
+400
+00:31:22,530 --> 00:31:29,390
+الخارجي لعضلة القلبأما ال abdominal area فعنا فيه
+
+401
+00:31:29,390 --> 00:31:34,730
+ال visceral portion هذه بتكون على ال surface بتكون
+
+402
+00:31:34,730 --> 00:31:37,870
+محيطة بالأحجار اللي هي زي ال lung زي ال liver زي
+
+403
+00:31:37,870 --> 00:31:41,450
+السلين و غيرهم أما ال visceral portion بتكون ناحيت
+
+404
+00:31:41,450 --> 00:31:45,990
+للخارج أكتر ال parietal قصدي فهي بتحيط ال
+
+405
+00:31:45,990 --> 00:31:50,610
+abdominal cavity بصفة عامة و بتتسمى ال peritoneum
+
+406
+00:31:50,610 --> 00:31:55,440
+يبقى parietal اسمهاالـ Visceral Peritoneum
+
+407
+00:31:55,440 --> 00:32:00,300
+والبرايتل البريتونيوم والكافيتى اسمها Peritoneal
+
+408
+00:32:00,300 --> 00:32:04,360
+Cavity اللى موجود فيها السائل المصلي او الـ Serous
+
+409
+00:32:04,360 --> 00:32:08,960
+اذا فلوت وطبعا الرسم التوضيحى هذا بالتدقيق فيه
+
+410
+00:32:08,960 --> 00:32:13,820
+هلاقي ان فيه اكتر من ممبران ممبران ملاصق مثلا للـ
+
+411
+00:32:13,820 --> 00:32:17,800
+lungs وممبران على الجزء الخارجى و بينهم full of
+
+412
+00:32:18,070 --> 00:32:23,430
+اللي هو ال sirus fluid وهذه عضلة في القلب اللي
+
+413
+00:32:23,430 --> 00:32:27,210
+انتوا شايفيها برضه فيها اكتر من مبرنة، المبرنة
+
+414
+00:32:27,210 --> 00:32:31,690
+الملاصقة بريكارديا و البرايتل بريكارديا و بالنص ال
+
+415
+00:32:31,690 --> 00:32:34,030
+sirus fluid
+
+416
+00:32:42,240 --> 00:32:47,460
+وهذا الرسم يعني بالألوان بيوضح أكتر عمليات الفصل
+
+417
+00:32:47,460 --> 00:32:52,840
+هذه ما بين الأحشاء الداخلية حتى ما تختلط مع بعضها
+
+418
+00:32:52,840 --> 00:32:56,580
+لحظة تسمع كتير أنه في واحد والله عنده فتق في
+
+419
+00:32:56,580 --> 00:33:01,440
+الحجاب الحاجز في عنده حاجة pleuritis في حاجة اسمها
+
+420
+00:33:01,440 --> 00:33:05,160
+pneumonia في حاجة اسمها يعني أشياء pneumothorax
+
+421
+00:33:05,160 --> 00:33:09,240
+معناه أنه فيه دخل الهواء على منطقة البلورة وعملوا
+
+422
+00:33:09,240 --> 00:33:13,450
+هذه المشاكل كلها بتكون مؤلمةو مزعجة و لو مثلا صار
+
+423
+00:33:13,450 --> 00:33:18,510
+فيه النفاتق في أحد الأغش هذه و طلع القضوء منه
+
+424
+00:33:18,510 --> 00:33:23,010
+بيسبب قلم كتير و بيعمل ارتجاع و مشكلات كتير كتير
+
+425
+00:33:23,010 --> 00:33:28,630
+طبعا قسموا عشان يسهلوا عملية الوصف للأحشاء و عملية
+
+426
+00:33:28,630 --> 00:33:33,020
+قدرة ال .. ال .. خدعنا نقول ال surgeons اللياللي
+
+427
+00:33:33,020 --> 00:33:36,960
+هم الجرحين على أنهم يدخلوا المناطق فقسموه ال
+
+428
+00:33:36,960 --> 00:33:42,180
+abdominal لأربع quadrant يعني لأربع أربع طبعا في
+
+429
+00:33:42,180 --> 00:33:45,960
+عندنا ال upper و في عندنا ال lower ففي طالما احنا
+
+430
+00:33:45,960 --> 00:33:48,940
+بنتكلم عن upper و عن lower و في عندنا left و في
+
+431
+00:33:48,940 --> 00:33:52,520
+عندنا right فصار في عندنا ال upper right upper
+
+432
+00:33:52,520 --> 00:33:56,600
+quadrant اللي هو بيكون فوق عندنا right lower
+
+433
+00:33:56,600 --> 00:34:00,880
+quadrant اللي بيكون لتحت و كذلك left upper و left
+
+434
+00:34:00,880 --> 00:34:08,030
+lowerو هذه طبعا هذه التقسيمة بتساعدي كتير في تحديد
+
+435
+00:34:08,030 --> 00:34:11,590
+المشكلات وين موجودة ال location تبع الأحشاء اللي
+
+436
+00:34:11,590 --> 00:34:14,770
+موجودة اللي من خلالها لو كان في ألم معين لو كان
+
+437
+00:34:14,770 --> 00:34:18,790
+inflammation معين نقدر نحدد المكان هذا إيش موجود
+
+438
+00:34:18,790 --> 00:34:23,510
+فيه و نقدر نشخص المشكلات اللي ممكن يواجهها الصحية
+
+439
+00:34:23,510 --> 00:34:26,390
+اللي موجهها الأشخاص طبعا في عندنا الفيسر في عندنا
+
+440
+00:34:26,390 --> 00:34:30,630
+ال midlineو هنا عاملين خط على أساس transversal
+
+441
+00:34:30,630 --> 00:34:36,230
+plan فبيقسم هذه لأربع أربع هذا بالنسبة ل ال
+
+442
+00:34:36,230 --> 00:34:44,190
+abdominal طبعا قسموا ال abdomen ل regions و هاد ال
+
+443
+00:34:44,190 --> 00:34:50,010
+regions طبعا عملوها تسعة regionsويلها مسمياتها
+
+444
+00:34:50,010 --> 00:34:53,210
+الخاصة طبعا في منها ال left و في منها ال right و
+
+445
+00:34:53,210 --> 00:34:56,990
+فيها الأشياء اللي موجودة في ال .. الوسط زي ال
+
+446
+00:34:56,990 --> 00:35:00,630
+amplitus region منطقة الصرة احنا بنسميها هذه بتكون
+
+447
+00:35:00,630 --> 00:35:06,410
+في وسط ال abdominal cavity هذه لحالها أخدت عملت
+
+448
+00:35:06,410 --> 00:35:13,320
+رقم فردي خلينا نسميهال .. ال other divisions أو
+
+449
+00:35:13,320 --> 00:35:18,040
+other regions زي ال right hypochondric region
+
+450
+00:35:18,040 --> 00:35:24,620
+منطقة لتحت ال ribs سموها right hypochondric region
+
+451
+00:35:24,620 --> 00:35:27,780
+منطقة ال lumber ال lumber احنا بنعرف منطقة ال back
+
+452
+00:35:27,780 --> 00:35:30,260
+او lower lower back ال lumber region او المنطقة
+
+453
+00:35:30,260 --> 00:35:34,080
+القطانية هذه ففي هذه المنطقة سموها ال right lumber
+
+454
+00:35:34,080 --> 00:35:37,580
+regionوالرايت الياك انجوايل المنطقة الانجوايل
+
+455
+00:35:37,580 --> 00:35:42,100
+الهادي اللي هي فيها كتير من ال blood vessels و ال
+
+456
+00:35:42,100 --> 00:35:47,020
+arteries و ال vein و ال lymph nodes و غيرها في
+
+457
+00:35:47,020 --> 00:35:53,490
+عندنا ال epigastric منطقة الالأعلى المعدة اللي هي
+
+458
+00:35:53,490 --> 00:35:57,850
+واضحة عنا بهذا الشكل هنا هنا الambulicus ال hypo
+
+459
+00:35:57,850 --> 00:36:05,210
+hypo gastric تحت المعدة و ال lift هلاقيتها بنرجع
+
+460
+00:36:05,210 --> 00:36:11,310
+مرة تانيةالكندرياك و ال .. و ال lumber region و ال
+
+461
+00:36:11,310 --> 00:36:16,530
+.. و ال .. و ال Iliac region بس على ال left side
+
+462
+00:36:16,530 --> 00:36:20,670
+عشان هيك صاروا فيه عندنا تسعة regions احنا بنتكلم
+
+463
+00:36:20,670 --> 00:36:28,440
+عنهم وهذه الصورة بتوضح أكتر المناطقوين وجودها هي
+
+464
+00:36:28,440 --> 00:36:32,700
+ال ابكاسترك حوالين المعدة الامبالايتس حوالين اللي
+
+465
+00:36:32,700 --> 00:36:36,960
+هي السرعة ال pubic region منطقة اللي هي الحوض أو
+
+466
+00:36:36,960 --> 00:36:41,700
+أسفل البطن ال right groin منطقة ال groin المنطقة
+
+467
+00:36:41,700 --> 00:36:46,620
+هذه اللي موجودة في الجسم و ال hypochondriac ال
+
+468
+00:36:46,620 --> 00:36:52,680
+right and left hypochondriacان شاء الله تكون هاي
+
+469
+00:36:52,680 --> 00:36:57,300
+اخر محاضرة اخر slide لعينها طبعا بشكركم ان شاء
+
+470
+00:36:57,300 --> 00:37:00,420
+الله على حسن استماعك و بتمنا ان هاي المحاضرات تكون
+
+471
+00:37:00,420 --> 00:37:04,320
+مفيدة للكم و اي استفسار انا نزلت على المجموعة ال
+
+472
+00:37:04,320 --> 00:37:08,340
+whats اني انا موجودة بكون يوم سبت و اتنين في
+
+473
+00:37:08,340 --> 00:37:12,400
+الجامعة اي حد بحب يتواصل معايا اهلا و سهلا و
+
+474
+00:37:12,400 --> 00:37:13,200
+يعطيكم العافية
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/WwomYcta6-8_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/WwomYcta6-8_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..9bfa2ee24ad6774ca5e8ffd4fd558621a7df8efb
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/WwomYcta6-8_postprocess.srt
@@ -0,0 +1,1680 @@
+1
+00:00:04,980 --> 00:00:09,220
+بسم الله الرحمن الرحيم محاضرتنا اليوم من الرابعة
+
+2
+00:00:09,220 --> 00:00:14,300
+في مساق التشريح علم التشريح اتكلم فيها عن
+
+3
+00:00:14,300 --> 00:00:17,540
+connective tissue هي type من ال tissue الموجودة في
+
+4
+00:00:17,540 --> 00:00:22,320
+الجسم واتفقنا انه من المحاضرة السابقة انه types of
+
+5
+00:00:22,320 --> 00:00:28,040
+tissue عندنا four types او four main types في
+
+6
+00:00:28,040 --> 00:00:36,070
+عندنا ال epithelialtissue و في عندنا ال connective
+
+7
+00:00:36,070 --> 00:00:47,650
+tissue و في عندنا ال muscle أو ال muscular tissue
+
+8
+00:00:47,650 --> 00:00:54,890
+و في عندنا ال nervous أو ال nerve tissue
+
+9
+00:00:57,800 --> 00:01:01,300
+تحدثنا في المرة السابقة عن ال epithelial cells
+
+10
+00:01:01,300 --> 00:01:06,500
+ووظفتها .. epithelial tissue ووظفتها و الأماكن
+
+11
+00:01:06,500 --> 00:01:10,100
+اللي وجدتها وقلنا إن هي بتملأ كل ال cavities بتعمل
+
+12
+00:01:10,100 --> 00:01:14,300
+covering لكل ال body بتملأ كل ال cavities وكل
+
+13
+00:01:14,300 --> 00:01:19,680
+القنوات اللي موجودة في الجسماليوم هنتكلم عن ال
+
+14
+00:01:19,680 --> 00:01:24,720
+connective tissue هي عبارة عن الأنسجة أو نسيج
+
+15
+00:01:24,720 --> 00:01:29,300
+الضام و طبعا هي نوع من أنواع ال tissue اللي widely
+
+16
+00:01:29,300 --> 00:01:37,520
+distributed في الجسم mostly abundant وكمانهي إلها
+
+17
+00:01:37,520 --> 00:01:42,420
+عدة وظائف هنتعرف عنها عليها ان شاء الله من خلال
+
+18
+00:01:42,420 --> 00:01:47,920
+محاضرتنا لليوم، طبعاً إلها مكوناتها الخاصة وإلها
+
+19
+00:01:47,920 --> 00:01:54,220
+وظائفها الخاصة وبالتالي هي انتشارها بتساعد على
+
+20
+00:01:54,220 --> 00:02:00,000
+بناء الجسمإيش بدنا نشبه ال connective tissue ده من
+
+21
+00:02:00,000 --> 00:02:06,300
+اسمه نسيج الدعم اللي هو بيركب كل مكونات الجسم هذه
+
+22
+00:02:06,300 --> 00:02:12,720
+مع بعضها بدنا نحاول نشبهها بالجسم ال body build زي
+
+23
+00:02:12,720 --> 00:02:20,420
+ال structure البناء تبعت المبنى إيش مكونات أي بناء
+
+24
+00:02:20,420 --> 00:02:27,970
+موجود عندناالو أكتر من مكون لازم يكون فيه أرض و
+
+25
+00:02:27,970 --> 00:02:31,350
+لازم يكون أرض و أساسات و لازم يكون فيه عندان و
+
+26
+00:02:31,350 --> 00:02:36,130
+لازم يكون فيه طوب عشان يعني يغلق الهيكل و يعمل
+
+27
+00:02:36,130 --> 00:02:44,410
+الهيكل هذا و يكون متكامل يعني لو احنا أخدنا مبنى و
+
+28
+00:02:44,410 --> 00:02:53,790
+صفطنا طوب طوب طوب تمام فوق بعضهمبدون ما نربط هذا
+
+29
+00:02:53,790 --> 00:02:59,170
+الطوب مع بعضه، إيش بيصير؟ بيصير المبنى في مهد
+
+30
+00:02:59,170 --> 00:03:04,790
+بالريح، بوقع إذا ما مكناش إحكام هذا الطوب مع بعضه
+
+31
+00:03:04,790 --> 00:03:09,590
+وماعملنالوش أساس .. أساس ومارفعنالوش عمدان، هذا
+
+32
+00:03:09,590 --> 00:03:14,810
+المبنى بيكون كتير ضعيف وواهي يبقى اسمه إيش وظيفة
+
+33
+00:03:14,810 --> 00:03:20,530
+ال connective tissue في الجسم؟ هي bending تاتيني
+
+34
+00:03:21,450 --> 00:03:27,130
+بتعطيني ال structure الوظيفة خلينا نقول هنا واحد
+
+35
+00:03:27,130 --> 00:03:33,130
+function بتعطيني
+
+36
+00:03:33,130 --> 00:03:37,390
+ال structure كمان
+
+37
+00:03:37,390 --> 00:03:47,150
+بتعطيني ال protection تحمي كمان
+
+38
+00:03:48,250 --> 00:03:51,910
+قلنا الـ Epithelial cell موجود تحت ايش بيكون
+
+39
+00:03:51,910 --> 00:03:55,470
+connective tissue اتقاذ ال structure عن بعضها
+
+40
+00:03:55,470 --> 00:04:00,470
+Insulating Insulation
+
+41
+00:04:00,470 --> 00:04:08,370
+ايش كمان ممكن يكون في عنا immune system تعطيني
+
+42
+00:04:08,370 --> 00:04:09,670
+immune مناعة
+
+43
+00:04:16,480 --> 00:04:25,280
+ايش كمان ممكن تعطيني storage بتعملي storage للمواد
+
+44
+00:04:25,280 --> 00:04:31,800
+الغذائية الموجودة في الجسم يبقى
+
+45
+00:04:31,800 --> 00:04:37,520
+هذه وظيفة ال connective tissue bend and support
+
+46
+00:04:37,520 --> 00:04:43,600
+the strength of the body كل ال bodyبتركبوا مع بعضه
+
+47
+00:04:43,600 --> 00:04:49,800
+و بتجعلوا متماسك protect and insulate internal
+
+48
+00:04:49,800 --> 00:04:55,680
+organs بتحمي هال organs الداخلية و بتعزلها عن
+
+49
+00:04:55,680 --> 00:05:01,240
+بعضها عشان مايصارش كل الجسم من جوا مخلوط
+
+50
+00:05:04,350 --> 00:05:07,530
+Convertmentalize Convertmentalize إيش يعني؟ عندي
+
+51
+00:05:07,530 --> 00:05:12,290
+العضلات موجودة كلها تحت الجلد، تمام؟ طيب، تحت
+
+52
+00:05:12,290 --> 00:05:15,570
+الجلد في عندنا مجموعة من العضلات وكل عضلة إلها
+
+53
+00:05:15,570 --> 00:05:19,670
+function لو اختلطت العضلات هذه، بصير الحركة صعبة
+
+54
+00:05:19,670 --> 00:05:26,910
+فبتعزل ال tendon sheets بتعزل عن طريق الأغشية اللي
+
+55
+00:05:26,910 --> 00:05:31,170
+موجودة هذه العضلات عن بعضها حتى تتحقق الوظائف
+
+56
+00:05:31,170 --> 00:05:36,970
+المطلوبة منهاtransport اه هانا نسينا
+
+57
+00:05:36,970 --> 00:05:42,390
+transportation transportation
+
+58
+00:05:42,390 --> 00:05:49,570
+وظيفة الدم بينقل المواد الغذائية والأكسجم في الجسم
+
+59
+00:05:49,570 --> 00:05:58,090
+site of store energyبيخزن اللي بيد اللي بيعطينا
+
+60
+00:05:58,090 --> 00:06:01,230
+energy كل ال tissue في الجسم محتاجة ل energy to
+
+61
+00:06:01,230 --> 00:06:05,150
+function main site of نيوم لأنه فيها الفاغو
+
+62
+00:06:05,150 --> 00:06:11,690
+سايتوسس هدول ال connective tissue ايش تركبتهم
+
+63
+00:06:11,690 --> 00:06:15,990
+حكينا احنا عن البناء البناء بيكون في عندنا ال
+
+64
+00:06:15,990 --> 00:06:21,050
+ground و بيكون في عندنا اعمدة و بيكون في عندنا
+
+65
+00:06:21,050 --> 00:06:31,260
+الطوب اللي بيربطوبيعمل شكل للمكان تمام لو روحنا
+
+66
+00:06:31,260 --> 00:06:38,220
+على ال connective tissue في عنا three main parts
+
+67
+00:06:38,220 --> 00:06:45,680
+او components ال ground substance هنقول ايش هي هي
+
+68
+00:06:45,680 --> 00:06:48,260
+خلينا نقول الأرضية اللي موجودة عليها هذه ال
+
+69
+00:06:48,260 --> 00:06:53,760
+connective tissue في عنا ال fibers وهي عبارة عن
+
+70
+00:06:53,760 --> 00:07:04,460
+الأعمدةاللي بتمتد عشان تعمل شكل أو تقطي سواء كان
+
+71
+00:07:04,460 --> 00:07:08,580
+ال solidity أو ال flexibility لجزء اللي هي موجودة
+
+72
+00:07:08,580 --> 00:07:12,260
+فيه وطبعا ال tissue لأنه احنا قولنا ال tissue هي
+
+73
+00:07:12,260 --> 00:07:14,700
+عبارة عن مجموعة من cells
+
+74
+00:07:17,330 --> 00:07:20,150
+يبقى في عندنا ال ground substance في عندنا ال
+
+75
+00:07:20,150 --> 00:07:24,670
+fibers في عندنا ال cells ال cells هذه هي المواد
+
+76
+00:07:24,670 --> 00:07:29,110
+الآئمة اللي بتمثل الطوب في البناء تمام؟ الطوب و
+
+77
+00:07:29,110 --> 00:07:32,690
+الزلط و الحصة و الأشياء اللي بيخلطوا فيها المكون
+
+78
+00:07:32,690 --> 00:07:37,430
+عشان يعملوا ال mattress طيب هذه الاتنين مع بعض ال
+
+79
+00:07:37,430 --> 00:07:42,630
+fibers و ال ground substance فهم عبارة عن matrix
+
+80
+00:07:42,630 --> 00:07:45,870
+طيب
+
+81
+00:07:46,590 --> 00:07:52,230
+Matrix اللي هي عبارة عن مصفوفة هذه المصفوفة اسمها
+
+82
+00:07:52,230 --> 00:07:56,230
+بتتكون من ال ground substances و ال fibers اللي
+
+83
+00:07:56,230 --> 00:08:01,110
+بتكون متواجدة عليها أو متركبة عليها ال cells هذه
+
+84
+00:08:01,110 --> 00:08:05,530
+عشان هذه اسمها cells يبقى هذه extracellular
+
+85
+00:08:05,530 --> 00:08:10,570
+extracellular تمام؟ هذه اتسمت ال ground substance
+
+86
+00:08:10,570 --> 00:08:16,780
+مع ال fibers هي ال extracellular matrixطيب نقعد
+
+87
+00:08:16,780 --> 00:08:22,000
+عشان نشوف كل واحدة من هدول إيش تركبتها طبعا
+
+88
+00:08:22,000 --> 00:08:26,980
+extracellular matrix ممكن تكون مادة جيلاتينية
+
+89
+00:08:26,980 --> 00:08:35,320
+موجودة في المكان عشان تنوجد فيها ال cells طيب يبقى
+
+90
+00:08:35,320 --> 00:08:37,640
+connective tissue هي three main components ال
+
+91
+00:08:37,640 --> 00:08:42,260
+ground substance ال fibers and the cellstogether
+
+92
+00:08:42,260 --> 00:08:45,920
+the ground substance and fibers make up the
+
+93
+00:08:45,920 --> 00:08:53,400
+extracellular matrix ال extracellular matrix أو هي
+
+94
+00:08:53,400 --> 00:08:59,520
+المصفوفة لخارج ال cells unstructural
+
+95
+00:08:59,520 --> 00:09:03,500
+material fills the spaces between the cells يبقى
+
+96
+00:09:03,500 --> 00:09:08,690
+في عندي قاعدة زي الجليك كدهموجود فيها اتخيلوا
+
+97
+00:09:08,690 --> 00:09:12,670
+انتوا في عندنا قبق بيركس في جيليه وموجود فيه قطع
+
+98
+00:09:12,670 --> 00:09:16,310
+من الفراولة
+
+99
+00:09:16,310 --> 00:09:20,810
+الموز زي ما بنعمل بعض الجيليه هذه هي ال ground
+
+100
+00:09:20,810 --> 00:09:25,690
+substance اللي بده تكون موجود فيها ال cells طبعا
+
+101
+00:09:25,690 --> 00:09:31,690
+هي created by cells بتعطينا consistency لال liquid
+
+102
+00:09:32,820 --> 00:09:37,840
+ممكن تكون داريزي from liquid to gel to solid يعني
+
+103
+00:09:37,840 --> 00:09:43,480
+ممكن تكون liquid خالص زي الدم ممكن تكون gel و ممكن
+
+104
+00:09:43,480 --> 00:09:49,860
+تكون solid جامدة ال
+
+105
+00:09:49,860 --> 00:09:54,160
+fibers المكون التاني لل extra cellular هي ال
+
+106
+00:09:54,160 --> 00:10:00,060
+fibers وهي بتتكون من ال collagen و
+
+107
+00:10:01,680 --> 00:10:08,000
+الـ elastane fibers و ال reticular fibers الـ
+
+108
+00:10:08,000 --> 00:10:12,540
+collision كتير بنسمع احنا ايش هو ال collision؟ هي
+
+109
+00:10:12,540 --> 00:10:18,670
+عبارة عنfilaments أو fibers المكون الأساسي اللي
+
+110
+00:10:18,670 --> 00:10:23,550
+عندها ال protein ال collagen أو ال protein نوع من
+
+111
+00:10:23,550 --> 00:10:28,730
+أنواع ال protein هو اسمه ال collagen ال collagen
+
+112
+00:10:28,730 --> 00:10:35,730
+هذا ايش خصائصه انه بيعطيني tensile strength يعني
+
+113
+00:10:35,730 --> 00:10:43,690
+نقدرش نشده بقاوم اي mechanicalخلّيني أقول
+
+114
+00:10:43,690 --> 00:10:51,530
+compression أو tensile يعني الشد بقاوم الشد طبعا
+
+115
+00:10:51,530 --> 00:10:57,190
+منتشر جدا abundant in the dense connective tissue
+
+116
+00:10:58,390 --> 00:11:01,750
+hold structure together بيعمل على تماثق الـ
+
+117
+00:11:01,750 --> 00:11:06,070
+structure هذه موجودة في الـ tendon and ligaments
+
+118
+00:11:06,070 --> 00:11:09,170
+tendon and ligaments هذه من خصائص الـ
+
+119
+00:11:09,170 --> 00:11:14,090
+musculoskeletal system مكون أساسي الـ tendon من
+
+120
+00:11:14,090 --> 00:11:17,570
+مكونات العضلات اللي هي بتعمل عملية السحب و الشد
+
+121
+00:11:17,570 --> 00:11:24,640
+اللي هي بتمثل ال movementلأن في عندى انا bone في
+
+122
+00:11:24,640 --> 00:11:28,520
+عندى joints في عندى muscles هي ال muscles هي عن
+
+123
+00:11:28,520 --> 00:11:33,460
+طريق تسحب هذه ال bone عسى استعمال الحركة المطلوبة
+
+124
+00:11:33,460 --> 00:11:36,780
+منين ال ligament وين موجودة؟ ال ligament هي عبارة
+
+125
+00:11:36,780 --> 00:11:41,260
+عن الأربطة اللى موجودة بين two adjacent bone حتى
+
+126
+00:11:41,260 --> 00:11:48,020
+تتكون للمفصل او ال joints in a reticular عن طريق
+
+127
+00:11:48,020 --> 00:11:54,050
+شبكةvery thin collagenous fibers highly branched
+
+128
+00:11:54,050 --> 00:11:57,530
+يعني بنقدر نقول ان ال collagen هذا
+
+129
+00:12:00,190 --> 00:12:04,350
+عبارة عن fibers هي مجموعة من ال fibers بتتراس و
+
+130
+00:12:04,350 --> 00:12:07,790
+بتكون بهذا الشكل زي الحبل بتبقى عاملة حبل هي
+
+131
+00:12:07,790 --> 00:12:13,670
+elastic بس مش .. مش كتير هي فيها elasticity اي
+
+132
+00:12:13,670 --> 00:12:16,610
+structure لازم يكون يتمتع بجزء من ال elasticity
+
+133
+00:12:16,610 --> 00:12:21,850
+حتى يقاوم ال compressions او the tensile strength
+
+134
+00:12:21,850 --> 00:12:26,470
+او قاوم mechanical forces اللي ممكن تيجي عليه اما
+
+135
+00:12:26,470 --> 00:12:28,530
+ال reticular فهي متشعبة
+
+136
+00:12:31,900 --> 00:12:39,120
+بهذا الشكل بتبقى عاملة زى الشبكة هكذا طيب elastic
+
+137
+00:12:39,120 --> 00:12:43,500
+ولا non-elastic؟ نعم هي very thin collagenous
+
+138
+00:12:43,500 --> 00:12:46,700
+fibers لكن highly branched
+
+139
+00:12:48,540 --> 00:12:52,640
+network بتعمل عاملة زي الشبكة هذه provide support
+
+140
+00:12:52,640 --> 00:12:56,660
+for the wall of blood vessels يبقى برضه هي elastic
+
+141
+00:12:56,660 --> 00:13:01,840
+طبعا ممكن أنها بتكون فيها جزء من المرونة أما ال
+
+142
+00:13:01,840 --> 00:13:09,440
+elastic fibers فهي نوعا من ال fibers المنتشرة جدا
+
+143
+00:13:09,440 --> 00:13:17,470
+microfilaments كتير thinكمان فيها كتير من ال
+
+144
+00:13:17,470 --> 00:13:23,910
+الستين اللي بيساعد على المرونة فها دي بتكون عاملة
+
+145
+00:13:23,910 --> 00:13:30,070
+زي هيك يعني تمام؟
+
+146
+00:13:30,070 --> 00:13:35,960
+بهذه الشكلاحنا محتاج المرونة هذه مثلا في ال vocal
+
+147
+00:13:35,960 --> 00:13:40,160
+cords لأن هي بتعتمد على الاهتزاز لو تخيلنا احنا ال
+
+148
+00:13:40,160 --> 00:13:44,320
+vocal cord هذي من ال collision fibers كيف الاهتزاز
+
+149
+00:13:44,320 --> 00:13:48,780
+بده يصير عشان عملية الصوت هذي تطلع ال air passages
+
+150
+00:13:48,780 --> 00:13:52,740
+كمان تحتاج لل elasticity فهذا الموع من ال fibers
+
+151
+00:13:52,740 --> 00:13:58,160
+بتكون بتمثلها روح
+
+152
+00:13:58,160 --> 00:14:05,460
+لل Sims في انهانوع من ال cells ال fixed الموجودة
+
+153
+00:14:05,460 --> 00:14:11,240
+في المكان في نفس مكانها ودائما موجودة وفي عندنا ال
+
+154
+00:14:11,240 --> 00:14:19,540
+cells المتنقلة اللي بتتحرك من مكان لمكان وفي عندنا
+
+155
+00:14:19,540 --> 00:14:26,540
+ال cells ممكن تكون mature or immature في عندنا ال
+
+156
+00:14:26,540 --> 00:14:28,240
+suffix كنت بتتكلم عن ال plus
+
+157
+00:14:31,140 --> 00:14:36,100
+الفرق بين كلمة Plast وبين
+
+158
+00:14:36,100 --> 00:14:42,060
+كلمة Sites Sites
+
+159
+00:14:42,060 --> 00:14:46,100
+مثلا لو قلنا Fibrocytes أو Chondrocytes أو كذا
+
+160
+00:14:46,100 --> 00:14:51,100
+فمعنى mature هذه immature
+
+161
+00:14:53,920 --> 00:14:58,560
+تمام؟ كلمتي بلا ال suffix اللي هي الكلمة أو الأحرف
+
+162
+00:14:58,560 --> 00:15:05,300
+اللي في نهاية الكلمة بتدلل على إيش الكلمة ففي
+
+163
+00:15:05,300 --> 00:15:08,260
+عندنا من أنواع ال cells أو ال major type في عندنا
+
+164
+00:15:08,260 --> 00:15:14,610
+ال fibroblast هي fixed cell موجودة دائماmost
+
+165
+00:15:14,610 --> 00:15:19,630
+common cells large star shape شكلها زي شكل النجمة
+
+166
+00:15:19,630 --> 00:15:25,610
+و produce fibers لأن هى immature لما بتتشكل و
+
+167
+00:15:25,610 --> 00:15:30,170
+بتصير mature بتنضج تعمل ليه ال fibers اللى احنا
+
+168
+00:15:30,170 --> 00:15:40,410
+اللى متواجدة في الجسم المختلف اما ال muscles فهى
+
+169
+00:15:40,410 --> 00:15:46,410
+برضه fixedلكن موجودة في الأشياء المميعة في الدم
+
+170
+00:15:46,410 --> 00:15:52,010
+وبتعمل ليه release للهيبرين أو الهيستامين نروح
+
+171
+00:15:52,010 --> 00:15:59,330
+للماكروفاجز wandering cells wandering يعني متنقلة
+
+172
+00:15:59,330 --> 00:16:06,730
+روالة حالمة فيها الفايكوسايتك الفاجو سايتكلأنها
+
+173
+00:16:06,730 --> 00:16:11,210
+بتعمل vacocytosis بتعمل على تأكل وتهاجم أي بكتيريا
+
+174
+00:16:11,210 --> 00:16:15,690
+أو أي جسم قريب يدخل على الجسم مهمة كتير في حالة ال
+
+175
+00:16:15,690 --> 00:16:20,290
+injury أو ال infection حتى تخلص الجسم من أي نوع من
+
+176
+00:16:20,290 --> 00:16:21,830
+ال infection أو ال inflammation
+
+177
+00:16:41,880 --> 00:16:45,220
+طيب إيش أنواع ال connective tissue؟ فيه عندنا ال
+
+178
+00:16:45,220 --> 00:16:49,920
+proper و ال specialized ال proper خلينا نسميها ال
+
+179
+00:16:49,920 --> 00:16:54,850
+connective tissue الأساسيةالأساسية هي ال proper
+
+180
+00:16:54,850 --> 00:16:57,330
+أما ال specialized اللي هي اتشكلت في هذه ال
+
+181
+00:16:57,330 --> 00:17:01,790
+connective tissue عشان تكون المكون آخر اللي هو مثل
+
+182
+00:17:01,790 --> 00:17:06,970
+ال cartilage ال bone و ال blood طبعا احنا بنلاحظ
+
+183
+00:17:06,970 --> 00:17:11,810
+بنلاحظ ان ال cartilage و ال bone و ال blood ال
+
+184
+00:17:11,810 --> 00:17:17,850
+solidity تبعتهم بتختلف ال bloodسائل الـ bone hard
+
+185
+00:17:17,850 --> 00:17:22,190
+صلب الـ cartilage بين البيانين في عندنا أنواع من
+
+186
+00:17:22,190 --> 00:17:24,290
+ال cartilage عندنا هتعرف عليها في منها ال elastic
+
+187
+00:17:24,290 --> 00:17:27,910
+منها ال yelling cartilage لكن هي فيها حقيقة مواد
+
+188
+00:17:27,910 --> 00:17:33,470
+غير صلبة هتعرف عليها في بداية محاضرتنا على الليلة
+
+189
+00:17:33,890 --> 00:17:36,290
+الـ connective tissue proper في منها الـ loose
+
+190
+00:17:36,290 --> 00:17:40,110
+منها ال adipose ال reticular ال dense و ال elastic
+
+191
+00:17:40,110 --> 00:17:47,170
+أنواع مختلفة من ال connective tissue proper منها
+
+192
+00:17:47,170 --> 00:17:54,290
+ال loose connective tissue mainly fibroblasts
+
+193
+00:17:54,290 --> 00:18:00,490
+لأنها المكون لسهخلايا غير نادجة fluid to gel-like
+
+194
+00:18:00,490 --> 00:18:05,050
+matrix يعني في منها السائلة المميعة على الآخر
+
+195
+00:18:05,050 --> 00:18:15,100
+ومنها الجل الهلامية أو ال gelatinous كله جنسو ال
+
+196
+00:18:15,100 --> 00:18:18,960
+elastic fibers bring the skin to the structure
+
+197
+00:18:18,960 --> 00:18:22,520
+بينيت طبعا في عندنا .. احنا في عندنا طبقة الجلد
+
+198
+00:18:22,520 --> 00:18:25,860
+بين الجلد في .. تحت الجلد في ال subcutaneous
+
+199
+00:18:25,860 --> 00:18:29,380
+tissue بعدها في عندنا موجود ال muscles و بعدها في
+
+200
+00:18:29,380 --> 00:18:33,540
+.. و كل مرة روحنا ديب نروحنا يعني ال .. ال deeper
+
+201
+00:18:33,540 --> 00:18:40,060
+tissue بنروح ل البو طبعا بتخذي هي تحتالـ
+
+202
+00:18:40,060 --> 00:18:44,020
+Epithelium اللي قلنا طبقة الخارجية بتعمل حلقة وصل
+
+203
+00:18:44,020 --> 00:18:50,280
+بتعمل فيها قنوات بتوصل على من الدم إلى ال tissue
+
+204
+00:18:50,280 --> 00:18:55,060
+هذه الموجودة that visit the nourishment near by
+
+205
+00:18:55,060 --> 00:19:00,220
+the epithelial cells and between the muscles وجودة
+
+206
+00:19:00,220 --> 00:19:05,800
+في عندنا ال membranes الموجودة بين العضلات أما ال
+
+207
+00:19:05,800 --> 00:19:11,740
+adiposeAdipocytes فيها خلايا دهنية بتعمل ال
+
+208
+00:19:11,740 --> 00:19:15,360
+cushions ايش وظيفة ال cushions دايما انها تعمل ال
+
+209
+00:19:15,360 --> 00:19:19,180
+shock absorption ال cushions دائما لما يصير فيه
+
+210
+00:19:19,180 --> 00:19:22,280
+mechanical compression فهي بتعمل shock absorption
+
+211
+00:19:22,280 --> 00:19:28,960
+على المكان Insulators بتعمل العزل كمان Story fat
+
+212
+00:19:29,840 --> 00:19:35,940
+لأنها بتخزن لفات موجودة under the skin behind the
+
+213
+00:19:35,940 --> 00:19:40,140
+eyeballs around the kidney and the head حتى تعمل
+
+214
+00:19:40,140 --> 00:19:46,020
+على حمايتها أما reticular reticular connective
+
+215
+00:19:46,020 --> 00:19:50,940
+tissue composed of reticular fibers supporting the
+
+216
+00:19:50,940 --> 00:19:56,020
+internal organs لأنها بتعمل زي شبكة كده محيطة وهي
+
+217
+00:19:56,020 --> 00:20:02,240
+موجود عندنا بعض الأشكال لإلهاwall of the liver and
+
+218
+00:20:02,240 --> 00:20:08,540
+spleen and lymphatic organs أما الـ dense tissue
+
+219
+00:20:08,540 --> 00:20:14,340
+باعد collagen fibers بتعمل على تمسكها أكتر، فيها
+
+220
+00:20:14,340 --> 00:20:18,440
+elastic fibers، a few fibroblasts، بين the body
+
+221
+00:20:18,440 --> 00:20:23,420
+part وقدر تمسك ال body part، تندعو، لجمين، درمس،
+
+222
+00:20:23,420 --> 00:20:26,620
+وهي poorly in blood supply
+
+223
+00:20:31,670 --> 00:20:36,010
+الـ elastic connective tissue موجودة ومنتشرة
+
+224
+00:20:36,010 --> 00:20:39,930
+abound in the elastic fibers فيها بعض الـcollagen
+
+225
+00:20:39,930 --> 00:20:44,230
+عشان يعمل شوية support فيها fibroblasts attached
+
+226
+00:20:44,230 --> 00:20:49,890
+between the bones توصل أو بتعمل عملية التصاق أو
+
+227
+00:20:49,890 --> 00:20:55,370
+وصل للبون walls of the arteries and airway and
+
+228
+00:20:55,370 --> 00:20:59,270
+heart البون فهي أصبحت osseous
+
+229
+00:21:02,590 --> 00:21:06,390
+العدل اكتر اشي صلب في ال muscle skeletal system
+
+230
+00:21:06,390 --> 00:21:11,470
+فبتعطيني solid matrix بتعطيني support protection
+
+231
+00:21:11,470 --> 00:21:19,070
+حماية forms blood cells ليش؟ لأنه احنا في ال bone
+
+232
+00:21:19,070 --> 00:21:23,550
+ال bone ما هو اللي بيعمل synthesis ل blood cells
+
+233
+00:21:23,550 --> 00:21:28,710
+attachment for muscle and skeleton معرفين ان كل
+
+234
+00:21:28,710 --> 00:21:33,150
+العضلاتموجودة وين فيها origin وفيها insertion ال
+
+235
+00:21:33,150 --> 00:21:35,010
+insertion و ال origin هدول اللي لازم يكونوا
+
+236
+00:21:35,010 --> 00:21:37,750
+مشبوكين بالعضل مقولك كيف العضله بتكون سابحة كده
+
+237
+00:21:37,750 --> 00:21:42,410
+عشان تقدر تعمل pull على مثلا خدنا نقول زي ال
+
+238
+00:21:42,410 --> 00:21:49,370
+biceps ال biceps بتعمل pull على الفرقر عشان تعمل
+
+239
+00:21:49,370 --> 00:21:57,730
+عملية reflection of the upper limb او البقى
+
+240
+00:22:02,780 --> 00:22:07,360
+نروح للوقت تاني من مكونات ال connective tissue
+
+241
+00:22:07,360 --> 00:22:13,180
+شوفنا ال boom في عندنا ال cartilage ال cartilage
+
+242
+00:22:13,180 --> 00:22:20,030
+قضها في ال boomflexible أكتر لإن هو بيقاوم two
+
+243
+00:22:20,030 --> 00:22:24,910
+kind of compressions tensile compression and two
+
+244
+00:22:24,910 --> 00:22:30,730
+kind of forces tensile and compression forces يعني
+
+245
+00:22:30,730 --> 00:22:34,410
+طبيعة المفصل لما بيكون العضمتين بيصير فيه
+
+246
+00:22:34,410 --> 00:22:38,550
+compression and tensile force بهذا الشكل لإن احنا
+
+247
+00:22:38,550 --> 00:22:44,740
+بدأت تتم العضمة فتروح تضغط دائما ال cartilageاللي
+
+248
+00:22:44,740 --> 00:22:47,660
+موجود under compression مع ال graphite يعني احنا
+
+249
+00:22:47,660 --> 00:22:50,980
+واقفين هي ال cartilage اللي موجود between two
+
+250
+00:22:50,980 --> 00:22:54,700
+adjacent points و احنا واقفين مثلا على ال lower
+
+251
+00:22:54,700 --> 00:22:58,920
+limb على ال knee على ال ankle على ال head فيه all
+
+252
+00:22:58,920 --> 00:23:03,240
+the time compression forces على المفاصل هذه او على
+
+253
+00:23:03,240 --> 00:23:07,180
+ال cartilage اللي موجود لو افترضناكمان أثناء
+
+254
+00:23:07,180 --> 00:23:12,200
+الحركة بتصير في احتكاك وكمان شد عليها دى فهو all
+
+255
+00:23:12,200 --> 00:23:16,720
+the time under mechanical forces لازم يكون الخواص
+
+256
+00:23:16,720 --> 00:23:21,700
+تبعته ابتدا يبقى weaker than bone more flexible
+
+257
+00:23:21,700 --> 00:23:23,100
+than bone
+
+258
+00:23:26,780 --> 00:23:30,420
+برضه منتشرة على شكل mattress ال cell type
+
+259
+00:23:30,420 --> 00:23:34,300
+chondroblast and chondrocyte ال chondroblast هي
+
+260
+00:23:34,300 --> 00:23:40,000
+لما بتكون قابلة للبناء لتعمل عملية البناء أما ال
+
+261
+00:23:40,000 --> 00:23:44,880
+chondrocyte هي mature لكن إيش الليالمميز لـ
+
+262
+00:23:44,880 --> 00:23:49,340
+Cartilage ان هو Avascular مافيش اي نوع من ال
+
+263
+00:23:49,340 --> 00:23:53,200
+Vascularization بدخل على ال Cartilage هذا عشان
+
+264
+00:23:53,200 --> 00:23:57,200
+هكذا عملية ال regeneration مش موجودة في ال
+
+265
+00:23:57,200 --> 00:23:59,760
+Cartilage يعني لما بيصير في عنا إصابة على ال
+
+266
+00:23:59,760 --> 00:24:03,400
+Cartilage اللي موجود في التسيمس و أقصار في عنا
+
+267
+00:24:03,550 --> 00:24:07,490
+إصابة مثلا في النيب في ال hip في ال elbow و أصيب
+
+268
+00:24:07,490 --> 00:24:10,530
+ال cartilage مافيش عملية regeneration ليش؟ لأنه
+
+269
+00:24:10,530 --> 00:24:13,870
+مافيش فيه vascularization هنسأل نفسنا طب هو كيف
+
+270
+00:24:13,870 --> 00:24:17,510
+بتغذى؟ فبتغذى عن طريق السوائل اللي بتكون موجودة
+
+271
+00:24:17,510 --> 00:24:21,130
+داخل ال cartilage هذي عملية ال compression بتطلع
+
+272
+00:24:21,130 --> 00:24:25,110
+السوائل في ال synovial fluid و بتاخد التغذية و
+
+273
+00:24:25,110 --> 00:24:28,830
+بترجع مرة تانية عشان هيك تغذية ال cartilage بتعتمد
+
+274
+00:24:28,830 --> 00:24:33,270
+على الحركةقدرش بيتحرك الجسم، قدرش بيكون فيه تقضية
+
+275
+00:24:33,270 --> 00:24:37,110
+لهذا ال .. ال cartilage ليش الشخص لما يكون
+
+276
+00:24:37,110 --> 00:24:41,030
+bedridden مابيتحركش كتير بيدعف عنده و بيكون عنده
+
+277
+00:24:41,030 --> 00:24:46,050
+risk في osteochondral process أو احنا بنسميه
+
+278
+00:24:46,050 --> 00:24:50,700
+ostearthritisليش؟ لأنه بيكون فيه العضم عنده أو الـ
+
+279
+00:24:50,700 --> 00:24:54,240
+cartilage ما بتهجوش التخضيه اللازمة لأنه مافيش
+
+280
+00:24:54,240 --> 00:24:56,940
+عملية compression and release اللي بتطلع السوائل
+
+281
+00:24:56,940 --> 00:25:04,280
+تاخد التخضيه وترجع على المكان طبعا إيش وظيفة ال
+
+282
+00:25:04,280 --> 00:25:08,320
+cartilage؟ subparts of tissue provided gliding
+
+283
+00:25:08,320 --> 00:25:12,580
+surface of the articulation لأن هو السطح المسؤول
+
+284
+00:25:12,580 --> 00:25:15,840
+احنا تخيل العضم فيها
+
+285
+00:25:17,830 --> 00:25:21,670
+العدم طبعا فيه إحساس، لو كان العضم بيحك في بعضه،
+
+286
+00:25:21,670 --> 00:25:24,850
+إيش بيصير دائما بيكون في عندنا ألم وفيش عندنا قدرة
+
+287
+00:25:24,850 --> 00:25:33,330
+على الحركة؟ انخلق كل عضمة عليها سطح من سطح أملسو
+
+288
+00:25:33,330 --> 00:25:38,590
+ناعم كده من ال cartilage هذا بيمنع الاحتكاك عساس
+
+289
+00:25:38,590 --> 00:25:42,230
+انه لما يصير في gliding لل bones on each others
+
+290
+00:25:42,230 --> 00:25:46,990
+تكون الحركة سهلة provide a model for formation of
+
+291
+00:25:46,990 --> 00:25:51,470
+most of the bone معناه ان ال immature bone بتكون
+
+292
+00:25:51,470 --> 00:25:56,510
+أصلها cartilage يعني عضام الأطفال قبل ما ال
+
+293
+00:25:56,510 --> 00:26:01,710
+maturationبتكون كلها أو معظمها غضبية في ابتنانه عن
+
+294
+00:26:01,710 --> 00:26:06,890
+طريق الـ Epiphyseal Plate اللي هو تكون عنصر النمو
+
+295
+00:26:06,890 --> 00:26:12,110
+في البون طبعا إيش ال types of cartilage؟ قلنا فيه
+
+296
+00:26:12,110 --> 00:26:16,900
+أنههو اكتر من نوع three types of cartilage في
+
+297
+00:26:16,900 --> 00:26:20,140
+الهيالين و ال fiber cartilage و ال elastic
+
+298
+00:26:20,140 --> 00:26:23,800
+cartilage نبدأ من الأخر ال elastic لو طلعنا على
+
+299
+00:26:23,800 --> 00:26:28,040
+الأذن سوان الأذن بنمسك وهو عبارة عن cartilage بس
+
+300
+00:26:28,040 --> 00:26:36,100
+طرد ال elastic ال fibers فيه كتيرة بتشكل طبعا ال
+
+301
+00:26:36,100 --> 00:26:42,310
+earالـ Respiratory Tracts Tubes زي التراكيا مثلا
+
+302
+00:26:42,310 --> 00:26:45,850
+إحنا لو حاسنا أنك بنحسها عبر عنق دروب نص مثلا
+
+303
+00:26:45,850 --> 00:26:50,180
+بحطنا إيدنا هنا بنلاقي هذه العضمة طريقةفهذه الـ
+
+304
+00:26:50,180 --> 00:26:53,980
+elastic أما الـ fibrocartilage فيها collagen
+
+305
+00:26:53,980 --> 00:26:58,740
+fibers زي الـ intervertebral discs أو الـ pupic
+
+306
+00:26:58,740 --> 00:27:02,660
+symphysis الـ intervertebral discs هناخده في ال ..
+
+307
+00:27:02,660 --> 00:27:05,580
+في ال Anatomy تبع ال skeletal system في عندنا ال
+
+308
+00:27:05,580 --> 00:27:11,160
+vertebra في عندنا between each adjacent vertebra
+
+309
+00:27:11,160 --> 00:27:14,980
+في
+
+310
+00:27:14,980 --> 00:27:20,360
+عندناالـ Vertebral Colon عبارة عن Vertebrae بين ال
+
+311
+00:27:20,360 --> 00:27:25,420
+Vertebrae هذه في انه Intervertebral disk وظيفته
+
+312
+00:27:25,420 --> 00:27:29,140
+يعمل shock absorption ويساعد على ان العمود الفقري
+
+313
+00:27:29,140 --> 00:27:37,750
+هذا يصير فيه حركة يبقى هذه بتكون زي كأنهاعازل ما
+
+314
+00:27:37,750 --> 00:27:41,230
+بينته ال vertebrae بيساعد على الحركة بيكون طريب
+
+315
+00:27:41,230 --> 00:27:44,670
+بيعمل shock absorption بحيث انه احنا زي ما قلتلكوا
+
+316
+00:27:44,670 --> 00:27:47,650
+احنا واقفين هيك دايما في ضغط من ال head على ال
+
+317
+00:27:47,650 --> 00:27:50,130
+shoulder على ال vertebral column بنتقل
+
+318
+00:27:50,130 --> 00:27:55,580
+transmission على ال two hipsهذه التركيبة بتخلي
+
+319
+00:27:55,580 --> 00:27:59,020
+الامتصاص الصدمات و ال weight bearing هذا اللي
+
+320
+00:27:59,020 --> 00:28:02,340
+دايما عن طريق الجاذبية بتجذبنا لتحت بيخلي الفراغ
+
+321
+00:28:02,340 --> 00:28:05,280
+هذا طبعا مع الكبر و مع السن بيفقد ال elasticity
+
+322
+00:28:05,280 --> 00:28:10,340
+تبعته و بيصير الألم و الأوجاع اللي بتصير عند الناس
+
+323
+00:28:10,890 --> 00:28:15,030
+طيب، كمان موجود في الـ biopic synthesis احنا بنعرف
+
+324
+00:28:15,030 --> 00:28:19,090
+ان الـ pelvic bones عبارة عن تلاتة عضمات منها لـ
+
+325
+00:28:19,090 --> 00:28:23,990
+pubis الـ pubis bone بيكون في مابينهم cartilage
+
+326
+00:28:23,990 --> 00:28:30,610
+يعني هذي اللي بتسمح بالتمدد لال .. يعني هي طبعا ال
+
+327
+00:28:30,610 --> 00:28:35,330
+.. ال fibro .. ال fibrosis هذي متسمحش كتير بالحركة
+
+328
+00:28:35,330 --> 00:28:40,270
+لكن موجودة بتفصل مابينها عن طريق ال fibrocartilage
+
+329
+00:28:40,760 --> 00:28:43,820
+أما الـ Healing cartilage الـ Healing cartilage هو
+
+330
+00:28:43,820 --> 00:28:48,280
+عبارة عن الـ cartilage اللي موجود بين two adjacent
+
+331
+00:28:48,280 --> 00:28:53,200
+bone movable bone يعني العضمات اللي بتتحرك كتير و
+
+332
+00:28:53,200 --> 00:28:57,460
+حركتها wide ال joints فيها بيكون Healing cartilage
+
+333
+00:28:57,460 --> 00:29:06,290
+هي متشر أكتر في الجسم has aبيريه كندريا ممبران
+
+334
+00:29:06,290 --> 00:29:09,730
+موجود في عندنا سينوفيا الفلويد نسمي السينوفيا
+
+335
+00:29:09,730 --> 00:29:14,130
+الممبران اللي بيبقى موجود في سينوفيا الفلويد هو
+
+336
+00:29:14,130 --> 00:29:15,170
+اللي بيغزه
+
+337
+00:29:18,660 --> 00:29:23,140
+بيغذي ال .. ال cartilage عن طريق الحركة بتطلع
+
+338
+00:29:23,140 --> 00:29:26,740
+السوائل من ال cartilage هذه بتاخد ال fluid بتاخد
+
+339
+00:29:26,740 --> 00:29:29,900
+ال nutrition و بتفوت على ال cartilage بتعطي
+
+340
+00:29:29,900 --> 00:29:37,240
+التغذية و معظم ال .. ال bones في بداية خلينا نقول
+
+341
+00:29:37,240 --> 00:29:41,740
+في الطفولة لحد السن النضوج بتكون هنين cartilage
+
+342
+00:29:42,230 --> 00:29:50,920
+وهذه بعض الأشغال من ال ..الـ cartilage نشوف عند ال
+
+343
+00:29:50,920 --> 00:29:54,480
+nose في عندنا ال elastic ال ear ال elastic
+
+344
+00:29:54,480 --> 00:30:00,400
+التراكيا ال elastic زي ما احنا شايفين في عندنا
+
+345
+00:30:00,400 --> 00:30:05,660
+الأزرق هذا كله cartilage هذا اللي في المفاصل هي
+
+346
+00:30:05,660 --> 00:30:10,180
+لين cartilage هنا ال pubis synthesis موجود عندنا
+
+347
+00:30:10,180 --> 00:30:16,530
+ال pubic fibrocartilage هنا between دهvertibrae زى
+
+348
+00:30:16,530 --> 00:30:20,550
+ما احنا شايفين فيه عندنا ال fibrocartilage ده
+
+349
+00:30:20,550 --> 00:30:25,810
+ممثلة بال intervertebral disc اما باقية المفاصل
+
+350
+00:30:25,810 --> 00:30:33,390
+فهي كلها هي lean cartilage روح
+
+351
+00:30:33,390 --> 00:30:39,970
+ل muscle tissue general
+
+352
+00:30:41,840 --> 00:30:46,220
+characteristics of muscle tissue اول فيها ان ال
+
+353
+00:30:46,220 --> 00:30:51,540
+muscle cell و ال muscle fibers من ميزتها انها
+
+354
+00:30:51,540 --> 00:30:55,900
+contractile ايش يعني contractile ان هي قابلة
+
+355
+00:30:55,900 --> 00:30:59,880
+لعملية ال contraction اللى بتقرب to adjacent bone
+
+356
+00:30:59,880 --> 00:31:04,060
+او كمان حتى لما بتبعد بتمنع سقوطها فعنا اكتر من
+
+357
+00:31:04,060 --> 00:31:08,220
+نوع من ال contraction ممكن تعمله ال muscle
+
+358
+00:31:10,190 --> 00:31:13,410
+يعني ال three type في ال skeletal في ال smooth في
+
+359
+00:31:13,410 --> 00:31:17,150
+ال cardiac ايش الفرق ما بينهم ال skeletal هي
+
+360
+00:31:17,150 --> 00:31:22,750
+العضلات اللي موجودة على ال bone نوعها striated and
+
+361
+00:31:22,750 --> 00:31:26,670
+voluntary movement يعني انا بقرر اتني ايدي باتنيها
+
+362
+00:31:26,670 --> 00:31:30,210
+احط ايدي ع راسي بحط ايدي ع راسي هذا كل باستخدام ال
+
+363
+00:31:30,210 --> 00:31:34,630
+skeletal muscles على أساس اني انا اقوم بالحركة
+
+364
+00:31:34,630 --> 00:31:39,460
+الambulation ال locomotionكل daily activity تبعت
+
+365
+00:31:39,460 --> 00:31:43,500
+الجسم هي بتكون فيها العضلات ال smooth muscle ال
+
+366
+00:31:43,500 --> 00:31:47,960
+skeletal muscle أما ال smooth هي مباطنة ل ال walls
+
+367
+00:31:47,960 --> 00:31:52,790
+of the organ كمان موجودة فيال role of the blood
+
+368
+00:31:52,790 --> 00:31:57,890
+vessel هي طبعا involuntary انا ما بقرر اني انا لا
+
+369
+00:31:57,890 --> 00:32:03,850
+اتحكم بعملية هدم ولا بعملية اخراج ولا كل هذه ال
+
+370
+00:32:03,850 --> 00:32:08,570
+smooth muscle involuntary and non-istriated ال
+
+371
+00:32:08,570 --> 00:32:14,930
+cardiac muscle هي عبارة عن العضلاء المكونة للقلب
+
+372
+00:32:14,930 --> 00:32:21,330
+هو القلب عبارة عن عضلةinvoluntary احنا مابنقررش
+
+373
+00:32:21,330 --> 00:32:24,510
+يدق قلبنا هلقت او مايدقش و يصير في عندنا دقة قلب
+
+374
+00:32:24,510 --> 00:32:28,250
+سريعة او دقة قلب بطيقة هذا اشي احنا مابنتحكم فيه
+
+375
+00:32:28,250 --> 00:32:29,150
+فهي serrated
+
+376
+00:32:37,850 --> 00:32:42,890
+intercalated شكل من أشكال كل نوع من أنواع ال
+
+377
+00:32:42,890 --> 00:32:47,450
+muscle ال skeletal muscle اللي فيها ال protein أو
+
+378
+00:32:47,450 --> 00:32:52,730
+فيها قرم الأكتين والميسين عشان تتمتع بخاصة ال
+
+379
+00:32:52,730 --> 00:32:57,610
+contractility لل smooth muscle اللي موجودة في
+
+380
+00:32:57,610 --> 00:33:01,630
+الأمعاء ومبطنة للجهاز الغضبى أما ال cardiac muscle
+
+381
+00:33:01,630 --> 00:33:07,200
+في القلبروح لآخر إشي من ال tissue اللي موجودة
+
+382
+00:33:07,200 --> 00:33:10,880
+معناه فهي nervous tissue اللي مسئولة عن ال
+
+383
+00:33:10,880 --> 00:33:15,540
+conduction عن عملية توصيل معلومات من ال brain لل
+
+384
+00:33:15,540 --> 00:33:19,140
+spinal cord لل other part of the body يبقى
+
+385
+00:33:19,140 --> 00:33:22,860
+sometimes termed as neural tissuefound in the
+
+386
+00:33:22,860 --> 00:33:26,240
+brain and spinal cord and peripheral nerves هنعرف
+
+387
+00:33:26,240 --> 00:33:31,360
+مكونات الجهاز العصبي ان شاء الله في حينها بتتكون
+
+388
+00:33:31,360 --> 00:33:33,960
+من ال neurons ال neurons هي عبارة عن أيه؟ ال
+
+389
+00:33:33,960 --> 00:33:37,940
+neurons هي الخلية العصبية اللي هي بتعمل عملية
+
+390
+00:33:37,940 --> 00:33:42,400
+conduction لتوصيل ال electricity زي مواصلات
+
+391
+00:33:42,400 --> 00:33:46,800
+الكهربا اللي موجودة consists of neurons or nerve
+
+392
+00:33:46,800 --> 00:33:51,620
+cellsو الـ glial cells اللي هي بتعمل ال supportive
+
+393
+00:33:51,620 --> 00:33:56,180
+tissue هذي موجودة ال supportive cell ي protect و ي
+
+394
+00:33:56,180 --> 00:34:02,660
+provide a framework of the neuron ال neuron طبعا
+
+395
+00:34:02,660 --> 00:34:06,400
+احنا كيف بنعرف ان الجو بارد او جو سخن مضطقه من
+
+396
+00:34:06,400 --> 00:34:10,280
+external stimulus انه والله انا دخلنا هنا في تكييف
+
+397
+00:34:10,280 --> 00:34:14,190
+فالجو هنا بارد بتروح على طولبيعمل توصيل للـ
+
+398
+00:34:14,190 --> 00:34:17,270
+impulse وبيعمل interpretation لأنه بيوصلها للدماغ،
+
+399
+00:34:17,270 --> 00:34:20,570
+للدماغ اللي بيترجمها وبيرجع بعدها الشعور اللي احنا
+
+400
+00:34:20,570 --> 00:34:24,950
+بنحس فيه أو بدنا ندفع حالنا أو بدنا نلبس أو غير،
+
+401
+00:34:24,950 --> 00:34:29,900
+يبقى detect stimuliprocess information quickly على
+
+402
+00:34:29,900 --> 00:34:33,220
+طول بتوصلها rapidly transmit electrical impulse
+
+403
+00:34:33,220 --> 00:34:39,240
+from one region of the body to another البرمينس ال
+
+404
+00:34:39,240 --> 00:34:43,920
+body function in control information processing
+
+405
+00:34:43,920 --> 00:34:48,950
+storage and retrieval internal communicationطبعا
+
+406
+00:34:48,950 --> 00:34:54,410
+احنا باستخدام أو بوجود الجهاز العصبي، بوجود ال
+
+407
+00:34:54,410 --> 00:35:00,090
+neurons هذه، بنقدر نكون أشخاص أصحاء، بنقدر نفسر
+
+408
+00:35:00,090 --> 00:35:04,150
+الشواهد اللي قدامنا، بنقدر نقوم خلينا نقول
+
+409
+00:35:04,150 --> 00:35:08,750
+بالحماية لأنفسنا، بنقدر نعمل ال .. ال function
+
+410
+00:35:08,750 --> 00:35:13,770
+اللي احنا بدنا يريها in a well coordinated manner
+
+411
+00:35:14,940 --> 00:35:19,340
+النيرون هو عبارة عن إيش؟ Process Extended from
+
+412
+00:35:19,340 --> 00:35:23,780
+Nerve Cell Body، فيه عندنا Dendrites وفي عندنا الـ
+
+413
+00:35:23,780 --> 00:35:26,140
+Axon زي ما إحنا شايفين فيه عندنا الـ Cell Body
+
+414
+00:35:26,140 --> 00:35:29,220
+اللي هو النوازم، إحنا شايفين هنا الـ Axon اللي هو
+
+415
+00:35:29,220 --> 00:35:32,960
+الشريط الطويل اللي موجود و الـ Dendrites هي عبارة
+
+416
+00:35:32,960 --> 00:35:37,980
+عن شبكة من الخلايا
+
+417
+00:35:37,980 --> 00:35:38,940
+أو خليني أقول
+
+418
+00:35:41,470 --> 00:35:46,130
+الوقت تستقبل ال impulse و احنا هنتكلم عنها
+
+419
+00:35:46,130 --> 00:35:50,250
+بالتفصيل لما نتحدث عن ال nervous system و يعطيكم
+
+420
+00:35:50,250 --> 00:35:53,910
+العافية و ماشوف كيف المحاضرة القادمة
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/WwomYcta6-8_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/WwomYcta6-8_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..bd33afcdc40dbc78728528a18b281dda03710516
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/WwomYcta6-8_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 3028, "start": 4.98, "end": 30.28, "text": "بسم الله الرحمن الرحيم محاضرتنا اليوم من الرابعة في مساق التشريح علم التشريح اتكلم فيها عن connective tissue هي type من ال tissue الموجودة في الجسم واتفقنا انه من المحاضرة السابقة انه types of tissue عندنا four types او four main types في عندنا ال epithelial", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 3714, 5016, 46958, 43500, 8315, 45595, 20498, 9154, 34892, 16758, 27884, 8978, 47524, 995, 4587, 16712, 8592, 16572, 5016, 11203, 2304, 16712, 8592, 16572, 5016, 1975, 2655, 4117, 19528, 8978, 11296, 18871, 1745, 488, 12404, 39896, 2010, 9154, 2423, 12404, 9673, 29245, 23328, 3660, 8978, 25724, 38251, 4032, 9307, 5172, 4587, 8315, 16472, 3224, 9154, 9673, 5016, 46958, 25720, 21136, 16758, 28671, 16472, 3224, 3467, 295, 12404, 43242, 8315, 1451, 3467, 1975, 2407, 1451, 2135, 3467, 8978, 43242, 8315, 2423, 2388, 355, 338, 831], "avg_logprob": -0.13954455484735204, "compression_ratio": 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أشخاص أصحاء، بنقدر نفسر الشواهد اللي قدامنا، بنقدر نقوم خلينا نقول بالحماية لأنفسنا، بنقدر نعمل ال .. ال function اللي احنا بدنا يريها in a well coordinated manner", "tokens": [9566, 3555, 3615, 995, 1975, 5016, 8315, 4724, 995, 14851, 9778, 3215, 10943, 34051, 4724, 29245, 23328, 25724, 3224, 31377, 18863, 9381, 21292, 12399, 4724, 29245, 23328, 2423, 22027, 29538, 12399, 44945, 28543, 2288, 8717, 30544, 5551, 8592, 9778, 33546, 5551, 9381, 5016, 16606, 12399, 44945, 28543, 2288, 8717, 36178, 2288, 25124, 14407, 3224, 3215, 13672, 1829, 12174, 3215, 10943, 8315, 12399, 44945, 28543, 2288, 8717, 4587, 20498, 16490, 1211, 9957, 995, 8717, 39648, 20666, 5016, 15042, 10632, 5296, 33456, 36178, 8315, 12399, 44945, 28543, 2288, 8717, 25957, 1211, 2423, 4386, 2423, 2445, 13672, 1829, 1975, 5016, 8315, 47525, 8315, 7251, 16572, 11296, 294, 257, 731, 29591, 9060], "avg_logprob": -0.13202408092831253, "compression_ratio": 1.7882882882882882, "no_speech_prob": 0.0, "words": [{"start": 2088.73, 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2130.46, "end": 2130.98, "word": " اللي", "probability": 0.6866455078125}, {"start": 2130.98, "end": 2131.42, "word": " موجود", "probability": 0.984375}, {"start": 2131.42, "end": 2131.6, "word": " و", "probability": 0.50439453125}, {"start": 2131.6, "end": 2131.72, "word": " الـ", "probability": 0.619873046875}, {"start": 2131.72, "end": 2132.24, "word": " Dendrites", "probability": 0.782958984375}, {"start": 2132.24, "end": 2132.54, "word": " هي", "probability": 0.85107421875}, {"start": 2132.54, "end": 2132.96, "word": " عبارة", "probability": 0.9974365234375}, {"start": 2132.96, "end": 2133.26, "word": " عن", "probability": 0.990234375}, {"start": 2133.26, "end": 2134.22, "word": " شبكة", "probability": 0.9964599609375}, {"start": 2134.22, "end": 2134.8, "word": " من", "probability": 0.99267578125}, {"start": 2134.8, "end": 2137.98, "word": " الخلايا", "probability": 0.9248046875}, {"start": 2137.98, "end": 2138.16, "word": " أو", "probability": 0.89013671875}, {"start": 2138.16, 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\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/WwomYcta6-8_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/WwomYcta6-8_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..9bfa2ee24ad6774ca5e8ffd4fd558621a7df8efb
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/WwomYcta6-8_raw.srt
@@ -0,0 +1,1680 @@
+1
+00:00:04,980 --> 00:00:09,220
+بسم الله الرحمن الرحيم محاضرتنا اليوم من الرابعة
+
+2
+00:00:09,220 --> 00:00:14,300
+في مساق التشريح علم التشريح اتكلم فيها عن
+
+3
+00:00:14,300 --> 00:00:17,540
+connective tissue هي type من ال tissue الموجودة في
+
+4
+00:00:17,540 --> 00:00:22,320
+الجسم واتفقنا انه من المحاضرة السابقة انه types of
+
+5
+00:00:22,320 --> 00:00:28,040
+tissue عندنا four types او four main types في
+
+6
+00:00:28,040 --> 00:00:36,070
+عندنا ال epithelialtissue و في عندنا ال connective
+
+7
+00:00:36,070 --> 00:00:47,650
+tissue و في عندنا ال muscle أو ال muscular tissue
+
+8
+00:00:47,650 --> 00:00:54,890
+و في عندنا ال nervous أو ال nerve tissue
+
+9
+00:00:57,800 --> 00:01:01,300
+تحدثنا في المرة السابقة عن ال epithelial cells
+
+10
+00:01:01,300 --> 00:01:06,500
+ووظفتها .. epithelial tissue ووظفتها و الأماكن
+
+11
+00:01:06,500 --> 00:01:10,100
+اللي وجدتها وقلنا إن هي بتملأ كل ال cavities بتعمل
+
+12
+00:01:10,100 --> 00:01:14,300
+covering لكل ال body بتملأ كل ال cavities وكل
+
+13
+00:01:14,300 --> 00:01:19,680
+القنوات اللي موجودة في الجسماليوم هنتكلم عن ال
+
+14
+00:01:19,680 --> 00:01:24,720
+connective tissue هي عبارة عن الأنسجة أو نسيج
+
+15
+00:01:24,720 --> 00:01:29,300
+الضام و طبعا هي نوع من أنواع ال tissue اللي widely
+
+16
+00:01:29,300 --> 00:01:37,520
+distributed في الجسم mostly abundant وكمانهي إلها
+
+17
+00:01:37,520 --> 00:01:42,420
+عدة وظائف هنتعرف عنها عليها ان شاء الله من خلال
+
+18
+00:01:42,420 --> 00:01:47,920
+محاضرتنا لليوم، طبعاً إلها مكوناتها الخاصة وإلها
+
+19
+00:01:47,920 --> 00:01:54,220
+وظائفها الخاصة وبالتالي هي انتشارها بتساعد على
+
+20
+00:01:54,220 --> 00:02:00,000
+بناء الجسمإيش بدنا نشبه ال connective tissue ده من
+
+21
+00:02:00,000 --> 00:02:06,300
+اسمه نسيج الدعم اللي هو بيركب كل مكونات الجسم هذه
+
+22
+00:02:06,300 --> 00:02:12,720
+مع بعضها بدنا نحاول نشبهها بالجسم ال body build زي
+
+23
+00:02:12,720 --> 00:02:20,420
+ال structure البناء تبعت المبنى إيش مكونات أي بناء
+
+24
+00:02:20,420 --> 00:02:27,970
+موجود عندناالو أكتر من مكون لازم يكون فيه أرض و
+
+25
+00:02:27,970 --> 00:02:31,350
+لازم يكون أرض و أساسات و لازم يكون فيه عندان و
+
+26
+00:02:31,350 --> 00:02:36,130
+لازم يكون فيه طوب عشان يعني يغلق الهيكل و يعمل
+
+27
+00:02:36,130 --> 00:02:44,410
+الهيكل هذا و يكون متكامل يعني لو احنا أخدنا مبنى و
+
+28
+00:02:44,410 --> 00:02:53,790
+صفطنا طوب طوب طوب تمام فوق بعضهمبدون ما نربط هذا
+
+29
+00:02:53,790 --> 00:02:59,170
+الطوب مع بعضه، إيش بيصير؟ بيصير المبنى في مهد
+
+30
+00:02:59,170 --> 00:03:04,790
+بالريح، بوقع إذا ما مكناش إحكام هذا الطوب مع بعضه
+
+31
+00:03:04,790 --> 00:03:09,590
+وماعملنالوش أساس .. أساس ومارفعنالوش عمدان، هذا
+
+32
+00:03:09,590 --> 00:03:14,810
+المبنى بيكون كتير ضعيف وواهي يبقى اسمه إيش وظيفة
+
+33
+00:03:14,810 --> 00:03:20,530
+ال connective tissue في الجسم؟ هي bending تاتيني
+
+34
+00:03:21,450 --> 00:03:27,130
+بتعطيني ال structure الوظيفة خلينا نقول هنا واحد
+
+35
+00:03:27,130 --> 00:03:33,130
+function بتعطيني
+
+36
+00:03:33,130 --> 00:03:37,390
+ال structure كمان
+
+37
+00:03:37,390 --> 00:03:47,150
+بتعطيني ال protection تحمي كمان
+
+38
+00:03:48,250 --> 00:03:51,910
+قلنا الـ Epithelial cell موجود تحت ايش بيكون
+
+39
+00:03:51,910 --> 00:03:55,470
+connective tissue اتقاذ ال structure عن بعضها
+
+40
+00:03:55,470 --> 00:04:00,470
+Insulating Insulation
+
+41
+00:04:00,470 --> 00:04:08,370
+ايش كمان ممكن يكون في عنا immune system تعطيني
+
+42
+00:04:08,370 --> 00:04:09,670
+immune مناعة
+
+43
+00:04:16,480 --> 00:04:25,280
+ايش كمان ممكن تعطيني storage بتعملي storage للمواد
+
+44
+00:04:25,280 --> 00:04:31,800
+الغذائية الموجودة في الجسم يبقى
+
+45
+00:04:31,800 --> 00:04:37,520
+هذه وظيفة ال connective tissue bend and support
+
+46
+00:04:37,520 --> 00:04:43,600
+the strength of the body كل ال bodyبتركبوا مع بعضه
+
+47
+00:04:43,600 --> 00:04:49,800
+و بتجعلوا متماسك protect and insulate internal
+
+48
+00:04:49,800 --> 00:04:55,680
+organs بتحمي هال organs الداخلية و بتعزلها عن
+
+49
+00:04:55,680 --> 00:05:01,240
+بعضها عشان مايصارش كل الجسم من جوا مخلوط
+
+50
+00:05:04,350 --> 00:05:07,530
+Convertmentalize Convertmentalize إيش يعني؟ عندي
+
+51
+00:05:07,530 --> 00:05:12,290
+العضلات موجودة كلها تحت الجلد، تمام؟ طيب، تحت
+
+52
+00:05:12,290 --> 00:05:15,570
+الجلد في عندنا مجموعة من العضلات وكل عضلة إلها
+
+53
+00:05:15,570 --> 00:05:19,670
+function لو اختلطت العضلات هذه، بصير الحركة صعبة
+
+54
+00:05:19,670 --> 00:05:26,910
+فبتعزل ال tendon sheets بتعزل عن طريق الأغشية اللي
+
+55
+00:05:26,910 --> 00:05:31,170
+موجودة هذه العضلات عن بعضها حتى تتحقق الوظائف
+
+56
+00:05:31,170 --> 00:05:36,970
+المطلوبة منهاtransport اه هانا نسينا
+
+57
+00:05:36,970 --> 00:05:42,390
+transportation transportation
+
+58
+00:05:42,390 --> 00:05:49,570
+وظيفة الدم بينقل المواد الغذائية والأكسجم في الجسم
+
+59
+00:05:49,570 --> 00:05:58,090
+site of store energyبيخزن اللي بيد اللي بيعطينا
+
+60
+00:05:58,090 --> 00:06:01,230
+energy كل ال tissue في الجسم محتاجة ل energy to
+
+61
+00:06:01,230 --> 00:06:05,150
+function main site of نيوم لأنه فيها الفاغو
+
+62
+00:06:05,150 --> 00:06:11,690
+سايتوسس هدول ال connective tissue ايش تركبتهم
+
+63
+00:06:11,690 --> 00:06:15,990
+حكينا احنا عن البناء البناء بيكون في عندنا ال
+
+64
+00:06:15,990 --> 00:06:21,050
+ground و بيكون في عندنا اعمدة و بيكون في عندنا
+
+65
+00:06:21,050 --> 00:06:31,260
+الطوب اللي بيربطوبيعمل شكل للمكان تمام لو روحنا
+
+66
+00:06:31,260 --> 00:06:38,220
+على ال connective tissue في عنا three main parts
+
+67
+00:06:38,220 --> 00:06:45,680
+او components ال ground substance هنقول ايش هي هي
+
+68
+00:06:45,680 --> 00:06:48,260
+خلينا نقول الأرضية اللي موجودة عليها هذه ال
+
+69
+00:06:48,260 --> 00:06:53,760
+connective tissue في عنا ال fibers وهي عبارة عن
+
+70
+00:06:53,760 --> 00:07:04,460
+الأعمدةاللي بتمتد عشان تعمل شكل أو تقطي سواء كان
+
+71
+00:07:04,460 --> 00:07:08,580
+ال solidity أو ال flexibility لجزء اللي هي موجودة
+
+72
+00:07:08,580 --> 00:07:12,260
+فيه وطبعا ال tissue لأنه احنا قولنا ال tissue هي
+
+73
+00:07:12,260 --> 00:07:14,700
+عبارة عن مجموعة من cells
+
+74
+00:07:17,330 --> 00:07:20,150
+يبقى في عندنا ال ground substance في عندنا ال
+
+75
+00:07:20,150 --> 00:07:24,670
+fibers في عندنا ال cells ال cells هذه هي المواد
+
+76
+00:07:24,670 --> 00:07:29,110
+الآئمة اللي بتمثل الطوب في البناء تمام؟ الطوب و
+
+77
+00:07:29,110 --> 00:07:32,690
+الزلط و الحصة و الأشياء اللي بيخلطوا فيها المكون
+
+78
+00:07:32,690 --> 00:07:37,430
+عشان يعملوا ال mattress طيب هذه الاتنين مع بعض ال
+
+79
+00:07:37,430 --> 00:07:42,630
+fibers و ال ground substance فهم عبارة عن matrix
+
+80
+00:07:42,630 --> 00:07:45,870
+طيب
+
+81
+00:07:46,590 --> 00:07:52,230
+Matrix اللي هي عبارة عن مصفوفة هذه المصفوفة اسمها
+
+82
+00:07:52,230 --> 00:07:56,230
+بتتكون من ال ground substances و ال fibers اللي
+
+83
+00:07:56,230 --> 00:08:01,110
+بتكون متواجدة عليها أو متركبة عليها ال cells هذه
+
+84
+00:08:01,110 --> 00:08:05,530
+عشان هذه اسمها cells يبقى هذه extracellular
+
+85
+00:08:05,530 --> 00:08:10,570
+extracellular تمام؟ هذه اتسمت ال ground substance
+
+86
+00:08:10,570 --> 00:08:16,780
+مع ال fibers هي ال extracellular matrixطيب نقعد
+
+87
+00:08:16,780 --> 00:08:22,000
+عشان نشوف كل واحدة من هدول إيش تركبتها طبعا
+
+88
+00:08:22,000 --> 00:08:26,980
+extracellular matrix ممكن تكون مادة جيلاتينية
+
+89
+00:08:26,980 --> 00:08:35,320
+موجودة في المكان عشان تنوجد فيها ال cells طيب يبقى
+
+90
+00:08:35,320 --> 00:08:37,640
+connective tissue هي three main components ال
+
+91
+00:08:37,640 --> 00:08:42,260
+ground substance ال fibers and the cellstogether
+
+92
+00:08:42,260 --> 00:08:45,920
+the ground substance and fibers make up the
+
+93
+00:08:45,920 --> 00:08:53,400
+extracellular matrix ال extracellular matrix أو هي
+
+94
+00:08:53,400 --> 00:08:59,520
+المصفوفة لخارج ال cells unstructural
+
+95
+00:08:59,520 --> 00:09:03,500
+material fills the spaces between the cells يبقى
+
+96
+00:09:03,500 --> 00:09:08,690
+في عندي قاعدة زي الجليك كدهموجود فيها اتخيلوا
+
+97
+00:09:08,690 --> 00:09:12,670
+انتوا في عندنا قبق بيركس في جيليه وموجود فيه قطع
+
+98
+00:09:12,670 --> 00:09:16,310
+من الفراولة
+
+99
+00:09:16,310 --> 00:09:20,810
+الموز زي ما بنعمل بعض الجيليه هذه هي ال ground
+
+100
+00:09:20,810 --> 00:09:25,690
+substance اللي بده تكون موجود فيها ال cells طبعا
+
+101
+00:09:25,690 --> 00:09:31,690
+هي created by cells بتعطينا consistency لال liquid
+
+102
+00:09:32,820 --> 00:09:37,840
+ممكن تكون داريزي from liquid to gel to solid يعني
+
+103
+00:09:37,840 --> 00:09:43,480
+ممكن تكون liquid خالص زي الدم ممكن تكون gel و ممكن
+
+104
+00:09:43,480 --> 00:09:49,860
+تكون solid جامدة ال
+
+105
+00:09:49,860 --> 00:09:54,160
+fibers المكون التاني لل extra cellular هي ال
+
+106
+00:09:54,160 --> 00:10:00,060
+fibers وهي بتتكون من ال collagen و
+
+107
+00:10:01,680 --> 00:10:08,000
+الـ elastane fibers و ال reticular fibers الـ
+
+108
+00:10:08,000 --> 00:10:12,540
+collision كتير بنسمع احنا ايش هو ال collision؟ هي
+
+109
+00:10:12,540 --> 00:10:18,670
+عبارة عنfilaments أو fibers المكون الأساسي اللي
+
+110
+00:10:18,670 --> 00:10:23,550
+عندها ال protein ال collagen أو ال protein نوع من
+
+111
+00:10:23,550 --> 00:10:28,730
+أنواع ال protein هو اسمه ال collagen ال collagen
+
+112
+00:10:28,730 --> 00:10:35,730
+هذا ايش خصائصه انه بيعطيني tensile strength يعني
+
+113
+00:10:35,730 --> 00:10:43,690
+نقدرش نشده بقاوم اي mechanicalخلّيني أقول
+
+114
+00:10:43,690 --> 00:10:51,530
+compression أو tensile يعني الشد بقاوم الشد طبعا
+
+115
+00:10:51,530 --> 00:10:57,190
+منتشر جدا abundant in the dense connective tissue
+
+116
+00:10:58,390 --> 00:11:01,750
+hold structure together بيعمل على تماثق الـ
+
+117
+00:11:01,750 --> 00:11:06,070
+structure هذه موجودة في الـ tendon and ligaments
+
+118
+00:11:06,070 --> 00:11:09,170
+tendon and ligaments هذه من خصائص الـ
+
+119
+00:11:09,170 --> 00:11:14,090
+musculoskeletal system مكون أساسي الـ tendon من
+
+120
+00:11:14,090 --> 00:11:17,570
+مكونات العضلات اللي هي بتعمل عملية السحب و الشد
+
+121
+00:11:17,570 --> 00:11:24,640
+اللي هي بتمثل ال movementلأن في عندى انا bone في
+
+122
+00:11:24,640 --> 00:11:28,520
+عندى joints في عندى muscles هي ال muscles هي عن
+
+123
+00:11:28,520 --> 00:11:33,460
+طريق تسحب هذه ال bone عسى استعمال الحركة المطلوبة
+
+124
+00:11:33,460 --> 00:11:36,780
+منين ال ligament وين موجودة؟ ال ligament هي عبارة
+
+125
+00:11:36,780 --> 00:11:41,260
+عن الأربطة اللى موجودة بين two adjacent bone حتى
+
+126
+00:11:41,260 --> 00:11:48,020
+تتكون للمفصل او ال joints in a reticular عن طريق
+
+127
+00:11:48,020 --> 00:11:54,050
+شبكةvery thin collagenous fibers highly branched
+
+128
+00:11:54,050 --> 00:11:57,530
+يعني بنقدر نقول ان ال collagen هذا
+
+129
+00:12:00,190 --> 00:12:04,350
+عبارة عن fibers هي مجموعة من ال fibers بتتراس و
+
+130
+00:12:04,350 --> 00:12:07,790
+بتكون بهذا الشكل زي الحبل بتبقى عاملة حبل هي
+
+131
+00:12:07,790 --> 00:12:13,670
+elastic بس مش .. مش كتير هي فيها elasticity اي
+
+132
+00:12:13,670 --> 00:12:16,610
+structure لازم يكون يتمتع بجزء من ال elasticity
+
+133
+00:12:16,610 --> 00:12:21,850
+حتى يقاوم ال compressions او the tensile strength
+
+134
+00:12:21,850 --> 00:12:26,470
+او قاوم mechanical forces اللي ممكن تيجي عليه اما
+
+135
+00:12:26,470 --> 00:12:28,530
+ال reticular فهي متشعبة
+
+136
+00:12:31,900 --> 00:12:39,120
+بهذا الشكل بتبقى عاملة زى الشبكة هكذا طيب elastic
+
+137
+00:12:39,120 --> 00:12:43,500
+ولا non-elastic؟ نعم هي very thin collagenous
+
+138
+00:12:43,500 --> 00:12:46,700
+fibers لكن highly branched
+
+139
+00:12:48,540 --> 00:12:52,640
+network بتعمل عاملة زي الشبكة هذه provide support
+
+140
+00:12:52,640 --> 00:12:56,660
+for the wall of blood vessels يبقى برضه هي elastic
+
+141
+00:12:56,660 --> 00:13:01,840
+طبعا ممكن أنها بتكون فيها جزء من المرونة أما ال
+
+142
+00:13:01,840 --> 00:13:09,440
+elastic fibers فهي نوعا من ال fibers المنتشرة جدا
+
+143
+00:13:09,440 --> 00:13:17,470
+microfilaments كتير thinكمان فيها كتير من ال
+
+144
+00:13:17,470 --> 00:13:23,910
+الستين اللي بيساعد على المرونة فها دي بتكون عاملة
+
+145
+00:13:23,910 --> 00:13:30,070
+زي هيك يعني تمام؟
+
+146
+00:13:30,070 --> 00:13:35,960
+بهذه الشكلاحنا محتاج المرونة هذه مثلا في ال vocal
+
+147
+00:13:35,960 --> 00:13:40,160
+cords لأن هي بتعتمد على الاهتزاز لو تخيلنا احنا ال
+
+148
+00:13:40,160 --> 00:13:44,320
+vocal cord هذي من ال collision fibers كيف الاهتزاز
+
+149
+00:13:44,320 --> 00:13:48,780
+بده يصير عشان عملية الصوت هذي تطلع ال air passages
+
+150
+00:13:48,780 --> 00:13:52,740
+كمان تحتاج لل elasticity فهذا الموع من ال fibers
+
+151
+00:13:52,740 --> 00:13:58,160
+بتكون بتمثلها روح
+
+152
+00:13:58,160 --> 00:14:05,460
+لل Sims في انهانوع من ال cells ال fixed الموجودة
+
+153
+00:14:05,460 --> 00:14:11,240
+في المكان في نفس مكانها ودائما موجودة وفي عندنا ال
+
+154
+00:14:11,240 --> 00:14:19,540
+cells المتنقلة اللي بتتحرك من مكان لمكان وفي عندنا
+
+155
+00:14:19,540 --> 00:14:26,540
+ال cells ممكن تكون mature or immature في عندنا ال
+
+156
+00:14:26,540 --> 00:14:28,240
+suffix كنت بتتكلم عن ال plus
+
+157
+00:14:31,140 --> 00:14:36,100
+الفرق بين كلمة Plast وبين
+
+158
+00:14:36,100 --> 00:14:42,060
+كلمة Sites Sites
+
+159
+00:14:42,060 --> 00:14:46,100
+مثلا لو قلنا Fibrocytes أو Chondrocytes أو كذا
+
+160
+00:14:46,100 --> 00:14:51,100
+فمعنى mature هذه immature
+
+161
+00:14:53,920 --> 00:14:58,560
+تمام؟ كلمتي بلا ال suffix اللي هي الكلمة أو الأحرف
+
+162
+00:14:58,560 --> 00:15:05,300
+اللي في نهاية الكلمة بتدلل على إيش الكلمة ففي
+
+163
+00:15:05,300 --> 00:15:08,260
+عندنا من أنواع ال cells أو ال major type في عندنا
+
+164
+00:15:08,260 --> 00:15:14,610
+ال fibroblast هي fixed cell موجودة دائماmost
+
+165
+00:15:14,610 --> 00:15:19,630
+common cells large star shape شكلها زي شكل النجمة
+
+166
+00:15:19,630 --> 00:15:25,610
+و produce fibers لأن هى immature لما بتتشكل و
+
+167
+00:15:25,610 --> 00:15:30,170
+بتصير mature بتنضج تعمل ليه ال fibers اللى احنا
+
+168
+00:15:30,170 --> 00:15:40,410
+اللى متواجدة في الجسم المختلف اما ال muscles فهى
+
+169
+00:15:40,410 --> 00:15:46,410
+برضه fixedلكن موجودة في الأشياء المميعة في الدم
+
+170
+00:15:46,410 --> 00:15:52,010
+وبتعمل ليه release للهيبرين أو الهيستامين نروح
+
+171
+00:15:52,010 --> 00:15:59,330
+للماكروفاجز wandering cells wandering يعني متنقلة
+
+172
+00:15:59,330 --> 00:16:06,730
+روالة حالمة فيها الفايكوسايتك الفاجو سايتكلأنها
+
+173
+00:16:06,730 --> 00:16:11,210
+بتعمل vacocytosis بتعمل على تأكل وتهاجم أي بكتيريا
+
+174
+00:16:11,210 --> 00:16:15,690
+أو أي جسم قريب يدخل على الجسم مهمة كتير في حالة ال
+
+175
+00:16:15,690 --> 00:16:20,290
+injury أو ال infection حتى تخلص الجسم من أي نوع من
+
+176
+00:16:20,290 --> 00:16:21,830
+ال infection أو ال inflammation
+
+177
+00:16:41,880 --> 00:16:45,220
+طيب إيش أنواع ال connective tissue؟ فيه عندنا ال
+
+178
+00:16:45,220 --> 00:16:49,920
+proper و ال specialized ال proper خلينا نسميها ال
+
+179
+00:16:49,920 --> 00:16:54,850
+connective tissue الأساسيةالأساسية هي ال proper
+
+180
+00:16:54,850 --> 00:16:57,330
+أما ال specialized اللي هي اتشكلت في هذه ال
+
+181
+00:16:57,330 --> 00:17:01,790
+connective tissue عشان تكون المكون آخر اللي هو مثل
+
+182
+00:17:01,790 --> 00:17:06,970
+ال cartilage ال bone و ال blood طبعا احنا بنلاحظ
+
+183
+00:17:06,970 --> 00:17:11,810
+بنلاحظ ان ال cartilage و ال bone و ال blood ال
+
+184
+00:17:11,810 --> 00:17:17,850
+solidity تبعتهم بتختلف ال bloodسائل الـ bone hard
+
+185
+00:17:17,850 --> 00:17:22,190
+صلب الـ cartilage بين البيانين في عندنا أنواع من
+
+186
+00:17:22,190 --> 00:17:24,290
+ال cartilage عندنا هتعرف عليها في منها ال elastic
+
+187
+00:17:24,290 --> 00:17:27,910
+منها ال yelling cartilage لكن هي فيها حقيقة مواد
+
+188
+00:17:27,910 --> 00:17:33,470
+غير صلبة هتعرف عليها في بداية محاضرتنا على الليلة
+
+189
+00:17:33,890 --> 00:17:36,290
+الـ connective tissue proper في منها الـ loose
+
+190
+00:17:36,290 --> 00:17:40,110
+منها ال adipose ال reticular ال dense و ال elastic
+
+191
+00:17:40,110 --> 00:17:47,170
+أنواع مختلفة من ال connective tissue proper منها
+
+192
+00:17:47,170 --> 00:17:54,290
+ال loose connective tissue mainly fibroblasts
+
+193
+00:17:54,290 --> 00:18:00,490
+لأنها المكون لسهخلايا غير نادجة fluid to gel-like
+
+194
+00:18:00,490 --> 00:18:05,050
+matrix يعني في منها السائلة المميعة على الآخر
+
+195
+00:18:05,050 --> 00:18:15,100
+ومنها الجل الهلامية أو ال gelatinous كله جنسو ال
+
+196
+00:18:15,100 --> 00:18:18,960
+elastic fibers bring the skin to the structure
+
+197
+00:18:18,960 --> 00:18:22,520
+بينيت طبعا في عندنا .. احنا في عندنا طبقة الجلد
+
+198
+00:18:22,520 --> 00:18:25,860
+بين الجلد في .. تحت الجلد في ال subcutaneous
+
+199
+00:18:25,860 --> 00:18:29,380
+tissue بعدها في عندنا موجود ال muscles و بعدها في
+
+200
+00:18:29,380 --> 00:18:33,540
+.. و كل مرة روحنا ديب نروحنا يعني ال .. ال deeper
+
+201
+00:18:33,540 --> 00:18:40,060
+tissue بنروح ل البو طبعا بتخذي هي تحتالـ
+
+202
+00:18:40,060 --> 00:18:44,020
+Epithelium اللي قلنا طبقة الخارجية بتعمل حلقة وصل
+
+203
+00:18:44,020 --> 00:18:50,280
+بتعمل فيها قنوات بتوصل على من الدم إلى ال tissue
+
+204
+00:18:50,280 --> 00:18:55,060
+هذه الموجودة that visit the nourishment near by
+
+205
+00:18:55,060 --> 00:19:00,220
+the epithelial cells and between the muscles وجودة
+
+206
+00:19:00,220 --> 00:19:05,800
+في عندنا ال membranes الموجودة بين العضلات أما ال
+
+207
+00:19:05,800 --> 00:19:11,740
+adiposeAdipocytes فيها خلايا دهنية بتعمل ال
+
+208
+00:19:11,740 --> 00:19:15,360
+cushions ايش وظيفة ال cushions دايما انها تعمل ال
+
+209
+00:19:15,360 --> 00:19:19,180
+shock absorption ال cushions دائما لما يصير فيه
+
+210
+00:19:19,180 --> 00:19:22,280
+mechanical compression فهي بتعمل shock absorption
+
+211
+00:19:22,280 --> 00:19:28,960
+على المكان Insulators بتعمل العزل كمان Story fat
+
+212
+00:19:29,840 --> 00:19:35,940
+لأنها بتخزن لفات موجودة under the skin behind the
+
+213
+00:19:35,940 --> 00:19:40,140
+eyeballs around the kidney and the head حتى تعمل
+
+214
+00:19:40,140 --> 00:19:46,020
+على حمايتها أما reticular reticular connective
+
+215
+00:19:46,020 --> 00:19:50,940
+tissue composed of reticular fibers supporting the
+
+216
+00:19:50,940 --> 00:19:56,020
+internal organs لأنها بتعمل زي شبكة كده محيطة وهي
+
+217
+00:19:56,020 --> 00:20:02,240
+موجود عندنا بعض الأشكال لإلهاwall of the liver and
+
+218
+00:20:02,240 --> 00:20:08,540
+spleen and lymphatic organs أما الـ dense tissue
+
+219
+00:20:08,540 --> 00:20:14,340
+باعد collagen fibers بتعمل على تمسكها أكتر، فيها
+
+220
+00:20:14,340 --> 00:20:18,440
+elastic fibers، a few fibroblasts، بين the body
+
+221
+00:20:18,440 --> 00:20:23,420
+part وقدر تمسك ال body part، تندعو، لجمين، درمس،
+
+222
+00:20:23,420 --> 00:20:26,620
+وهي poorly in blood supply
+
+223
+00:20:31,670 --> 00:20:36,010
+الـ elastic connective tissue موجودة ومنتشرة
+
+224
+00:20:36,010 --> 00:20:39,930
+abound in the elastic fibers فيها بعض الـcollagen
+
+225
+00:20:39,930 --> 00:20:44,230
+عشان يعمل شوية support فيها fibroblasts attached
+
+226
+00:20:44,230 --> 00:20:49,890
+between the bones توصل أو بتعمل عملية التصاق أو
+
+227
+00:20:49,890 --> 00:20:55,370
+وصل للبون walls of the arteries and airway and
+
+228
+00:20:55,370 --> 00:20:59,270
+heart البون فهي أصبحت osseous
+
+229
+00:21:02,590 --> 00:21:06,390
+العدل اكتر اشي صلب في ال muscle skeletal system
+
+230
+00:21:06,390 --> 00:21:11,470
+فبتعطيني solid matrix بتعطيني support protection
+
+231
+00:21:11,470 --> 00:21:19,070
+حماية forms blood cells ليش؟ لأنه احنا في ال bone
+
+232
+00:21:19,070 --> 00:21:23,550
+ال bone ما هو اللي بيعمل synthesis ل blood cells
+
+233
+00:21:23,550 --> 00:21:28,710
+attachment for muscle and skeleton معرفين ان كل
+
+234
+00:21:28,710 --> 00:21:33,150
+العضلاتموجودة وين فيها origin وفيها insertion ال
+
+235
+00:21:33,150 --> 00:21:35,010
+insertion و ال origin هدول اللي لازم يكونوا
+
+236
+00:21:35,010 --> 00:21:37,750
+مشبوكين بالعضل مقولك كيف العضله بتكون سابحة كده
+
+237
+00:21:37,750 --> 00:21:42,410
+عشان تقدر تعمل pull على مثلا خدنا نقول زي ال
+
+238
+00:21:42,410 --> 00:21:49,370
+biceps ال biceps بتعمل pull على الفرقر عشان تعمل
+
+239
+00:21:49,370 --> 00:21:57,730
+عملية reflection of the upper limb او البقى
+
+240
+00:22:02,780 --> 00:22:07,360
+نروح للوقت تاني من مكونات ال connective tissue
+
+241
+00:22:07,360 --> 00:22:13,180
+شوفنا ال boom في عندنا ال cartilage ال cartilage
+
+242
+00:22:13,180 --> 00:22:20,030
+قضها في ال boomflexible أكتر لإن هو بيقاوم two
+
+243
+00:22:20,030 --> 00:22:24,910
+kind of compressions tensile compression and two
+
+244
+00:22:24,910 --> 00:22:30,730
+kind of forces tensile and compression forces يعني
+
+245
+00:22:30,730 --> 00:22:34,410
+طبيعة المفصل لما بيكون العضمتين بيصير فيه
+
+246
+00:22:34,410 --> 00:22:38,550
+compression and tensile force بهذا الشكل لإن احنا
+
+247
+00:22:38,550 --> 00:22:44,740
+بدأت تتم العضمة فتروح تضغط دائما ال cartilageاللي
+
+248
+00:22:44,740 --> 00:22:47,660
+موجود under compression مع ال graphite يعني احنا
+
+249
+00:22:47,660 --> 00:22:50,980
+واقفين هي ال cartilage اللي موجود between two
+
+250
+00:22:50,980 --> 00:22:54,700
+adjacent points و احنا واقفين مثلا على ال lower
+
+251
+00:22:54,700 --> 00:22:58,920
+limb على ال knee على ال ankle على ال head فيه all
+
+252
+00:22:58,920 --> 00:23:03,240
+the time compression forces على المفاصل هذه او على
+
+253
+00:23:03,240 --> 00:23:07,180
+ال cartilage اللي موجود لو افترضناكمان أثناء
+
+254
+00:23:07,180 --> 00:23:12,200
+الحركة بتصير في احتكاك وكمان شد عليها دى فهو all
+
+255
+00:23:12,200 --> 00:23:16,720
+the time under mechanical forces لازم يكون الخواص
+
+256
+00:23:16,720 --> 00:23:21,700
+تبعته ابتدا يبقى weaker than bone more flexible
+
+257
+00:23:21,700 --> 00:23:23,100
+than bone
+
+258
+00:23:26,780 --> 00:23:30,420
+برضه منتشرة على شكل mattress ال cell type
+
+259
+00:23:30,420 --> 00:23:34,300
+chondroblast and chondrocyte ال chondroblast هي
+
+260
+00:23:34,300 --> 00:23:40,000
+لما بتكون قابلة للبناء لتعمل عملية البناء أما ال
+
+261
+00:23:40,000 --> 00:23:44,880
+chondrocyte هي mature لكن إيش الليالمميز لـ
+
+262
+00:23:44,880 --> 00:23:49,340
+Cartilage ان هو Avascular مافيش اي نوع من ال
+
+263
+00:23:49,340 --> 00:23:53,200
+Vascularization بدخل على ال Cartilage هذا عشان
+
+264
+00:23:53,200 --> 00:23:57,200
+هكذا عملية ال regeneration مش موجودة في ال
+
+265
+00:23:57,200 --> 00:23:59,760
+Cartilage يعني لما بيصير في عنا إصابة على ال
+
+266
+00:23:59,760 --> 00:24:03,400
+Cartilage اللي موجود في التسيمس و أقصار في عنا
+
+267
+00:24:03,550 --> 00:24:07,490
+إصابة مثلا في النيب في ال hip في ال elbow و أصيب
+
+268
+00:24:07,490 --> 00:24:10,530
+ال cartilage مافيش عملية regeneration ليش؟ لأنه
+
+269
+00:24:10,530 --> 00:24:13,870
+مافيش فيه vascularization هنسأل نفسنا طب هو كيف
+
+270
+00:24:13,870 --> 00:24:17,510
+بتغذى؟ فبتغذى عن طريق السوائل اللي بتكون موجودة
+
+271
+00:24:17,510 --> 00:24:21,130
+داخل ال cartilage هذي عملية ال compression بتطلع
+
+272
+00:24:21,130 --> 00:24:25,110
+السوائل في ال synovial fluid و بتاخد التغذية و
+
+273
+00:24:25,110 --> 00:24:28,830
+بترجع مرة تانية عشان هيك تغذية ال cartilage بتعتمد
+
+274
+00:24:28,830 --> 00:24:33,270
+على الحركةقدرش بيتحرك الجسم، قدرش بيكون فيه تقضية
+
+275
+00:24:33,270 --> 00:24:37,110
+لهذا ال .. ال cartilage ليش الشخص لما يكون
+
+276
+00:24:37,110 --> 00:24:41,030
+bedridden مابيتحركش كتير بيدعف عنده و بيكون عنده
+
+277
+00:24:41,030 --> 00:24:46,050
+risk في osteochondral process أو احنا بنسميه
+
+278
+00:24:46,050 --> 00:24:50,700
+ostearthritisليش؟ لأنه بيكون فيه العضم عنده أو الـ
+
+279
+00:24:50,700 --> 00:24:54,240
+cartilage ما بتهجوش التخضيه اللازمة لأنه مافيش
+
+280
+00:24:54,240 --> 00:24:56,940
+عملية compression and release اللي بتطلع السوائل
+
+281
+00:24:56,940 --> 00:25:04,280
+تاخد التخضيه وترجع على المكان طبعا إيش وظيفة ال
+
+282
+00:25:04,280 --> 00:25:08,320
+cartilage؟ subparts of tissue provided gliding
+
+283
+00:25:08,320 --> 00:25:12,580
+surface of the articulation لأن هو السطح المسؤول
+
+284
+00:25:12,580 --> 00:25:15,840
+احنا تخيل العضم فيها
+
+285
+00:25:17,830 --> 00:25:21,670
+العدم طبعا فيه إحساس، لو كان العضم بيحك في بعضه،
+
+286
+00:25:21,670 --> 00:25:24,850
+إيش بيصير دائما بيكون في عندنا ألم وفيش عندنا قدرة
+
+287
+00:25:24,850 --> 00:25:33,330
+على الحركة؟ انخلق كل عضمة عليها سطح من سطح أملسو
+
+288
+00:25:33,330 --> 00:25:38,590
+ناعم كده من ال cartilage هذا بيمنع الاحتكاك عساس
+
+289
+00:25:38,590 --> 00:25:42,230
+انه لما يصير في gliding لل bones on each others
+
+290
+00:25:42,230 --> 00:25:46,990
+تكون الحركة سهلة provide a model for formation of
+
+291
+00:25:46,990 --> 00:25:51,470
+most of the bone معناه ان ال immature bone بتكون
+
+292
+00:25:51,470 --> 00:25:56,510
+أصلها cartilage يعني عضام الأطفال قبل ما ال
+
+293
+00:25:56,510 --> 00:26:01,710
+maturationبتكون كلها أو معظمها غضبية في ابتنانه عن
+
+294
+00:26:01,710 --> 00:26:06,890
+طريق الـ Epiphyseal Plate اللي هو تكون عنصر النمو
+
+295
+00:26:06,890 --> 00:26:12,110
+في البون طبعا إيش ال types of cartilage؟ قلنا فيه
+
+296
+00:26:12,110 --> 00:26:16,900
+أنههو اكتر من نوع three types of cartilage في
+
+297
+00:26:16,900 --> 00:26:20,140
+الهيالين و ال fiber cartilage و ال elastic
+
+298
+00:26:20,140 --> 00:26:23,800
+cartilage نبدأ من الأخر ال elastic لو طلعنا على
+
+299
+00:26:23,800 --> 00:26:28,040
+الأذن سوان الأذن بنمسك وهو عبارة عن cartilage بس
+
+300
+00:26:28,040 --> 00:26:36,100
+طرد ال elastic ال fibers فيه كتيرة بتشكل طبعا ال
+
+301
+00:26:36,100 --> 00:26:42,310
+earالـ Respiratory Tracts Tubes زي التراكيا مثلا
+
+302
+00:26:42,310 --> 00:26:45,850
+إحنا لو حاسنا أنك بنحسها عبر عنق دروب نص مثلا
+
+303
+00:26:45,850 --> 00:26:50,180
+بحطنا إيدنا هنا بنلاقي هذه العضمة طريقةفهذه الـ
+
+304
+00:26:50,180 --> 00:26:53,980
+elastic أما الـ fibrocartilage فيها collagen
+
+305
+00:26:53,980 --> 00:26:58,740
+fibers زي الـ intervertebral discs أو الـ pupic
+
+306
+00:26:58,740 --> 00:27:02,660
+symphysis الـ intervertebral discs هناخده في ال ..
+
+307
+00:27:02,660 --> 00:27:05,580
+في ال Anatomy تبع ال skeletal system في عندنا ال
+
+308
+00:27:05,580 --> 00:27:11,160
+vertebra في عندنا between each adjacent vertebra
+
+309
+00:27:11,160 --> 00:27:14,980
+في
+
+310
+00:27:14,980 --> 00:27:20,360
+عندناالـ Vertebral Colon عبارة عن Vertebrae بين ال
+
+311
+00:27:20,360 --> 00:27:25,420
+Vertebrae هذه في انه Intervertebral disk وظيفته
+
+312
+00:27:25,420 --> 00:27:29,140
+يعمل shock absorption ويساعد على ان العمود الفقري
+
+313
+00:27:29,140 --> 00:27:37,750
+هذا يصير فيه حركة يبقى هذه بتكون زي كأنهاعازل ما
+
+314
+00:27:37,750 --> 00:27:41,230
+بينته ال vertebrae بيساعد على الحركة بيكون طريب
+
+315
+00:27:41,230 --> 00:27:44,670
+بيعمل shock absorption بحيث انه احنا زي ما قلتلكوا
+
+316
+00:27:44,670 --> 00:27:47,650
+احنا واقفين هيك دايما في ضغط من ال head على ال
+
+317
+00:27:47,650 --> 00:27:50,130
+shoulder على ال vertebral column بنتقل
+
+318
+00:27:50,130 --> 00:27:55,580
+transmission على ال two hipsهذه التركيبة بتخلي
+
+319
+00:27:55,580 --> 00:27:59,020
+الامتصاص الصدمات و ال weight bearing هذا اللي
+
+320
+00:27:59,020 --> 00:28:02,340
+دايما عن طريق الجاذبية بتجذبنا لتحت بيخلي الفراغ
+
+321
+00:28:02,340 --> 00:28:05,280
+هذا طبعا مع الكبر و مع السن بيفقد ال elasticity
+
+322
+00:28:05,280 --> 00:28:10,340
+تبعته و بيصير الألم و الأوجاع اللي بتصير عند الناس
+
+323
+00:28:10,890 --> 00:28:15,030
+طيب، كمان موجود في الـ biopic synthesis احنا بنعرف
+
+324
+00:28:15,030 --> 00:28:19,090
+ان الـ pelvic bones عبارة عن تلاتة عضمات منها لـ
+
+325
+00:28:19,090 --> 00:28:23,990
+pubis الـ pubis bone بيكون في مابينهم cartilage
+
+326
+00:28:23,990 --> 00:28:30,610
+يعني هذي اللي بتسمح بالتمدد لال .. يعني هي طبعا ال
+
+327
+00:28:30,610 --> 00:28:35,330
+.. ال fibro .. ال fibrosis هذي متسمحش كتير بالحركة
+
+328
+00:28:35,330 --> 00:28:40,270
+لكن موجودة بتفصل مابينها عن طريق ال fibrocartilage
+
+329
+00:28:40,760 --> 00:28:43,820
+أما الـ Healing cartilage الـ Healing cartilage هو
+
+330
+00:28:43,820 --> 00:28:48,280
+عبارة عن الـ cartilage اللي موجود بين two adjacent
+
+331
+00:28:48,280 --> 00:28:53,200
+bone movable bone يعني العضمات اللي بتتحرك كتير و
+
+332
+00:28:53,200 --> 00:28:57,460
+حركتها wide ال joints فيها بيكون Healing cartilage
+
+333
+00:28:57,460 --> 00:29:06,290
+هي متشر أكتر في الجسم has aبيريه كندريا ممبران
+
+334
+00:29:06,290 --> 00:29:09,730
+موجود في عندنا سينوفيا الفلويد نسمي السينوفيا
+
+335
+00:29:09,730 --> 00:29:14,130
+الممبران اللي بيبقى موجود في سينوفيا الفلويد هو
+
+336
+00:29:14,130 --> 00:29:15,170
+اللي بيغزه
+
+337
+00:29:18,660 --> 00:29:23,140
+بيغذي ال .. ال cartilage عن طريق الحركة بتطلع
+
+338
+00:29:23,140 --> 00:29:26,740
+السوائل من ال cartilage هذه بتاخد ال fluid بتاخد
+
+339
+00:29:26,740 --> 00:29:29,900
+ال nutrition و بتفوت على ال cartilage بتعطي
+
+340
+00:29:29,900 --> 00:29:37,240
+التغذية و معظم ال .. ال bones في بداية خلينا نقول
+
+341
+00:29:37,240 --> 00:29:41,740
+في الطفولة لحد السن النضوج بتكون هنين cartilage
+
+342
+00:29:42,230 --> 00:29:50,920
+وهذه بعض الأشغال من ال ..الـ cartilage نشوف عند ال
+
+343
+00:29:50,920 --> 00:29:54,480
+nose في عندنا ال elastic ال ear ال elastic
+
+344
+00:29:54,480 --> 00:30:00,400
+التراكيا ال elastic زي ما احنا شايفين في عندنا
+
+345
+00:30:00,400 --> 00:30:05,660
+الأزرق هذا كله cartilage هذا اللي في المفاصل هي
+
+346
+00:30:05,660 --> 00:30:10,180
+لين cartilage هنا ال pubis synthesis موجود عندنا
+
+347
+00:30:10,180 --> 00:30:16,530
+ال pubic fibrocartilage هنا between دهvertibrae زى
+
+348
+00:30:16,530 --> 00:30:20,550
+ما احنا شايفين فيه عندنا ال fibrocartilage ده
+
+349
+00:30:20,550 --> 00:30:25,810
+ممثلة بال intervertebral disc اما باقية المفاصل
+
+350
+00:30:25,810 --> 00:30:33,390
+فهي كلها هي lean cartilage روح
+
+351
+00:30:33,390 --> 00:30:39,970
+ل muscle tissue general
+
+352
+00:30:41,840 --> 00:30:46,220
+characteristics of muscle tissue اول فيها ان ال
+
+353
+00:30:46,220 --> 00:30:51,540
+muscle cell و ال muscle fibers من ميزتها انها
+
+354
+00:30:51,540 --> 00:30:55,900
+contractile ايش يعني contractile ان هي قابلة
+
+355
+00:30:55,900 --> 00:30:59,880
+لعملية ال contraction اللى بتقرب to adjacent bone
+
+356
+00:30:59,880 --> 00:31:04,060
+او كمان حتى لما بتبعد بتمنع سقوطها فعنا اكتر من
+
+357
+00:31:04,060 --> 00:31:08,220
+نوع من ال contraction ممكن تعمله ال muscle
+
+358
+00:31:10,190 --> 00:31:13,410
+يعني ال three type في ال skeletal في ال smooth في
+
+359
+00:31:13,410 --> 00:31:17,150
+ال cardiac ايش الفرق ما بينهم ال skeletal هي
+
+360
+00:31:17,150 --> 00:31:22,750
+العضلات اللي موجودة على ال bone نوعها striated and
+
+361
+00:31:22,750 --> 00:31:26,670
+voluntary movement يعني انا بقرر اتني ايدي باتنيها
+
+362
+00:31:26,670 --> 00:31:30,210
+احط ايدي ع راسي بحط ايدي ع راسي هذا كل باستخدام ال
+
+363
+00:31:30,210 --> 00:31:34,630
+skeletal muscles على أساس اني انا اقوم بالحركة
+
+364
+00:31:34,630 --> 00:31:39,460
+الambulation ال locomotionكل daily activity تبعت
+
+365
+00:31:39,460 --> 00:31:43,500
+الجسم هي بتكون فيها العضلات ال smooth muscle ال
+
+366
+00:31:43,500 --> 00:31:47,960
+skeletal muscle أما ال smooth هي مباطنة ل ال walls
+
+367
+00:31:47,960 --> 00:31:52,790
+of the organ كمان موجودة فيال role of the blood
+
+368
+00:31:52,790 --> 00:31:57,890
+vessel هي طبعا involuntary انا ما بقرر اني انا لا
+
+369
+00:31:57,890 --> 00:32:03,850
+اتحكم بعملية هدم ولا بعملية اخراج ولا كل هذه ال
+
+370
+00:32:03,850 --> 00:32:08,570
+smooth muscle involuntary and non-istriated ال
+
+371
+00:32:08,570 --> 00:32:14,930
+cardiac muscle هي عبارة عن العضلاء المكونة للقلب
+
+372
+00:32:14,930 --> 00:32:21,330
+هو القلب عبارة عن عضلةinvoluntary احنا مابنقررش
+
+373
+00:32:21,330 --> 00:32:24,510
+يدق قلبنا هلقت او مايدقش و يصير في عندنا دقة قلب
+
+374
+00:32:24,510 --> 00:32:28,250
+سريعة او دقة قلب بطيقة هذا اشي احنا مابنتحكم فيه
+
+375
+00:32:28,250 --> 00:32:29,150
+فهي serrated
+
+376
+00:32:37,850 --> 00:32:42,890
+intercalated شكل من أشكال كل نوع من أنواع ال
+
+377
+00:32:42,890 --> 00:32:47,450
+muscle ال skeletal muscle اللي فيها ال protein أو
+
+378
+00:32:47,450 --> 00:32:52,730
+فيها قرم الأكتين والميسين عشان تتمتع بخاصة ال
+
+379
+00:32:52,730 --> 00:32:57,610
+contractility لل smooth muscle اللي موجودة في
+
+380
+00:32:57,610 --> 00:33:01,630
+الأمعاء ومبطنة للجهاز الغضبى أما ال cardiac muscle
+
+381
+00:33:01,630 --> 00:33:07,200
+في القلبروح لآخر إشي من ال tissue اللي موجودة
+
+382
+00:33:07,200 --> 00:33:10,880
+معناه فهي nervous tissue اللي مسئولة عن ال
+
+383
+00:33:10,880 --> 00:33:15,540
+conduction عن عملية توصيل معلومات من ال brain لل
+
+384
+00:33:15,540 --> 00:33:19,140
+spinal cord لل other part of the body يبقى
+
+385
+00:33:19,140 --> 00:33:22,860
+sometimes termed as neural tissuefound in the
+
+386
+00:33:22,860 --> 00:33:26,240
+brain and spinal cord and peripheral nerves هنعرف
+
+387
+00:33:26,240 --> 00:33:31,360
+مكونات الجهاز العصبي ان شاء الله في حينها بتتكون
+
+388
+00:33:31,360 --> 00:33:33,960
+من ال neurons ال neurons هي عبارة عن أيه؟ ال
+
+389
+00:33:33,960 --> 00:33:37,940
+neurons هي الخلية العصبية اللي هي بتعمل عملية
+
+390
+00:33:37,940 --> 00:33:42,400
+conduction لتوصيل ال electricity زي مواصلات
+
+391
+00:33:42,400 --> 00:33:46,800
+الكهربا اللي موجودة consists of neurons or nerve
+
+392
+00:33:46,800 --> 00:33:51,620
+cellsو الـ glial cells اللي هي بتعمل ال supportive
+
+393
+00:33:51,620 --> 00:33:56,180
+tissue هذي موجودة ال supportive cell ي protect و ي
+
+394
+00:33:56,180 --> 00:34:02,660
+provide a framework of the neuron ال neuron طبعا
+
+395
+00:34:02,660 --> 00:34:06,400
+احنا كيف بنعرف ان الجو بارد او جو سخن مضطقه من
+
+396
+00:34:06,400 --> 00:34:10,280
+external stimulus انه والله انا دخلنا هنا في تكييف
+
+397
+00:34:10,280 --> 00:34:14,190
+فالجو هنا بارد بتروح على طولبيعمل توصيل للـ
+
+398
+00:34:14,190 --> 00:34:17,270
+impulse وبيعمل interpretation لأنه بيوصلها للدماغ،
+
+399
+00:34:17,270 --> 00:34:20,570
+للدماغ اللي بيترجمها وبيرجع بعدها الشعور اللي احنا
+
+400
+00:34:20,570 --> 00:34:24,950
+بنحس فيه أو بدنا ندفع حالنا أو بدنا نلبس أو غير،
+
+401
+00:34:24,950 --> 00:34:29,900
+يبقى detect stimuliprocess information quickly على
+
+402
+00:34:29,900 --> 00:34:33,220
+طول بتوصلها rapidly transmit electrical impulse
+
+403
+00:34:33,220 --> 00:34:39,240
+from one region of the body to another البرمينس ال
+
+404
+00:34:39,240 --> 00:34:43,920
+body function in control information processing
+
+405
+00:34:43,920 --> 00:34:48,950
+storage and retrieval internal communicationطبعا
+
+406
+00:34:48,950 --> 00:34:54,410
+احنا باستخدام أو بوجود الجهاز العصبي، بوجود ال
+
+407
+00:34:54,410 --> 00:35:00,090
+neurons هذه، بنقدر نكون أشخاص أصحاء، بنقدر نفسر
+
+408
+00:35:00,090 --> 00:35:04,150
+الشواهد اللي قدامنا، بنقدر نقوم خلينا نقول
+
+409
+00:35:04,150 --> 00:35:08,750
+بالحماية لأنفسنا، بنقدر نعمل ال .. ال function
+
+410
+00:35:08,750 --> 00:35:13,770
+اللي احنا بدنا يريها in a well coordinated manner
+
+411
+00:35:14,940 --> 00:35:19,340
+النيرون هو عبارة عن إيش؟ Process Extended from
+
+412
+00:35:19,340 --> 00:35:23,780
+Nerve Cell Body، فيه عندنا Dendrites وفي عندنا الـ
+
+413
+00:35:23,780 --> 00:35:26,140
+Axon زي ما إحنا شايفين فيه عندنا الـ Cell Body
+
+414
+00:35:26,140 --> 00:35:29,220
+اللي هو النوازم، إحنا شايفين هنا الـ Axon اللي هو
+
+415
+00:35:29,220 --> 00:35:32,960
+الشريط الطويل اللي موجود و الـ Dendrites هي عبارة
+
+416
+00:35:32,960 --> 00:35:37,980
+عن شبكة من الخلايا
+
+417
+00:35:37,980 --> 00:35:38,940
+أو خليني أقول
+
+418
+00:35:41,470 --> 00:35:46,130
+الوقت تستقبل ال impulse و احنا هنتكلم عنها
+
+419
+00:35:46,130 --> 00:35:50,250
+بالتفصيل لما نتحدث عن ال nervous system و يعطيكم
+
+420
+00:35:50,250 --> 00:35:53,910
+العافية و ماشوف كيف المحاضرة القادمة
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s.srt
new file mode 100644
index 0000000000000000000000000000000000000000..d1f8d02290caca014c03ae773ee7cba485b424a1
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s.srt
@@ -0,0 +1,1418 @@
+1
+00:00:05,110 --> 00:00:09,450
+بسم الله الرحمن الرحيم حضرتنا الثالثة في مساق ال
+
+2
+00:00:09,450 --> 00:00:12,770
+anatomy هنتكلم فيها عن الـ tissue level
+
+3
+00:00:12,770 --> 00:00:18,990
+organization موضوعنا اليوم أنواع الـ tissue طبعا زي
+
+4
+00:00:18,990 --> 00:00:23,250
+ما احنا عارفين أن مجموعة الـ cells قولنا المكون
+
+5
+00:00:23,250 --> 00:00:28,750
+الأساسي هي الـ cell مجموعة من الـ cells بتعملنا
+
+6
+00:00:28,750 --> 00:00:33,250
+tissue مجموعة من الـ tissue بتعمل organ
+
+7
+00:00:37,360 --> 00:00:43,060
+تمام؟ ومجموعة من الـ organs بتعملنا
+
+8
+00:00:43,060 --> 00:00:47,600
+الـ system و بعدين الـ system بيعمل الـ body فاحنا من
+
+9
+00:00:47,600 --> 00:00:54,600
+هان لهان اليوم هنتكلم عن أنواع الـ type of tissue
+
+10
+00:00:56,780 --> 00:01:00,680
+طبعا في عندنا four main types of tissue طبعا قولنا
+
+11
+00:01:00,680 --> 00:01:04,140
+مجموعة من الـ cells المتشابهة بتكون ليه؟ الـ tissue
+
+12
+00:01:04,140 --> 00:01:09,260
+بتكون from common embryologic origin and have the
+
+13
+00:01:09,260 --> 00:01:14,900
+same function طبعا هذا العلم اللي بيدرس الـ tissue
+
+14
+00:01:14,900 --> 00:01:19,280
+هو علم بنسميه احنا علم الـ histology طبعا عندنا four
+
+15
+00:01:19,280 --> 00:01:25,400
+types of tissue عندنا الـ epithelial
+
+16
+00:01:30,740 --> 00:01:37,160
+وعندنا الـ connective tissue وعندنا
+
+17
+00:01:37,160 --> 00:01:44,690
+الـ muscle tissue وعندنا الـ nerve tissue طبعا أربعة
+
+18
+00:01:44,690 --> 00:01:50,890
+type من الـ tissue هو مكون لأو خلينا نقول أنواع الـ
+
+19
+00:01:50,890 --> 00:01:54,270
+tissue اللي موجودة في الجسم اليوم تركزنا في
+
+20
+00:01:54,270 --> 00:01:59,150
+محاضرتنا على الـ epithelial tissue و أنواعها و
+
+21
+00:01:59,150 --> 00:02:03,650
+تركيبها و كيف احنا ممكن نتعرف على الوظيفة اللي هي
+
+22
+00:02:03,650 --> 00:02:04,830
+بتقدمها
+
+23
+00:02:06,860 --> 00:02:11,480
+الـ Epithelial tissue طبيعتها هي مسموها الخلايا
+
+24
+00:02:11,480 --> 00:02:16,840
+الطبقية موجودة تقريبا في كل أعضاء الجسم اللي هو
+
+25
+00:02:16,840 --> 00:02:22,560
+وظائف متعددة موجودة على الـ surface of the skin كمان
+
+26
+00:02:22,560 --> 00:02:26,680
+موجودة على كل الأماكن التجاويف إذا بنتذكر في محاضرة
+
+27
+00:02:26,680 --> 00:02:30,660
+الـ Anatomy الأولى قلنا فيه أن التجاويف الموجودة أو
+
+28
+00:02:30,660 --> 00:02:33,880
+الـ cavities اللي موجودة فهي مبطنة لكل الـ cavities
+
+29
+00:02:33,880 --> 00:02:38,120
+الموجودة في الجسم اللي هي الـ pleural cavity، الـ
+
+30
+00:02:38,120 --> 00:02:42,260
+cardiac، الـ peritoneum، الـ abdominal cavities كمان
+
+31
+00:02:42,260 --> 00:02:45,540
+موجودة في الـ ducts في كل القنوات اللي موجودة في
+
+32
+00:02:45,540 --> 00:02:50,540
+الجسم و بتكون مع بعض الـ glands يبقى هي الـ
+
+33
+00:02:50,540 --> 00:02:54,780
+epithelial cells هنتعرف على وظيفتها لما نبدأ فيها
+
+34
+00:02:54,780 --> 00:02:57,080
+لكن نروح على الـ connective tissue الـ connective
+
+35
+00:02:57,080 --> 00:03:00,240
+tissue الخلايا الضامة بيسموها الخلايا اللي بتربط
+
+36
+00:03:00,240 --> 00:03:06,860
+الأشياء مع بعضها في الجسم طبعا بتساعد و بتدعم الـ
+
+37
+00:03:06,860 --> 00:03:11,830
+structure سبعة الجسم all together and store energy
+
+38
+00:03:11,830 --> 00:03:18,050
+and كمان provide immune system طبعا الـ muscle
+
+39
+00:03:18,050 --> 00:03:22,190
+tissue الـ muscle tissue هي عبارة عن الخلية المكونة
+
+40
+00:03:22,190 --> 00:03:27,090
+للعضلات العضلات بما فيها الـ muscle نفسها و الـ
+
+41
+00:03:27,090 --> 00:03:30,260
+tendon و كل الـ connective tissues اللي حواليها لكن
+
+42
+00:03:30,260 --> 00:03:34,140
+احنا نتكلم عن العضلة العضلة هي نسيج خاص أما الـ
+
+43
+00:03:34,140 --> 00:03:40,200
+nerve tissue فهي العضلة المكونة لجهاز الـ sorry الـ
+
+44
+00:03:40,200 --> 00:03:45,500
+tissue المكونة لجهاز الـ nervous system طبيعتها
+
+45
+00:03:47,010 --> 00:03:53,170
+بتقدم عندنا الـ electricity نعرف أن الجسم عبارة
+
+46
+00:03:53,170 --> 00:03:57,590
+عن مواصلات بتوصل الـ orders من الدماغ الـ spinal
+
+47
+00:03:57,590 --> 00:04:03,290
+cord لـ الأطراف لجميع أجزاء الجسم فهي بتعملنا الـ
+
+48
+00:04:03,290 --> 00:04:06,830
+electrical signal detected change طبعا احنا لو
+
+49
+00:04:06,830 --> 00:04:10,910
+احنا طلعنا في جو بارد أو دخلنا على جو سخن كيف
+
+50
+00:04:10,910 --> 00:04:14,350
+جسمنا بتلقى هذه الإشارة بتلقاها عن طريق الـ nerve
+
+51
+00:04:14,350 --> 00:04:18,240
+tissueو الـ nerve cell نفسها كمان respond to
+
+52
+00:04:18,240 --> 00:04:22,480
+nervous impulses أي impulse بتيجي سواء عن طريق الـ
+
+53
+00:04:22,480 --> 00:04:25,340
+reflex مدينا ايدنا مسكنا حاجة ساخنة على طول احنا
+
+54
+00:04:25,340 --> 00:04:29,100
+بنرميها دعزنا على مسمار على طول بنبعد عنه أي
+
+55
+00:04:29,100 --> 00:04:32,960
+مشكلة ممكن تواجهنا مع الـ external environment أو
+
+56
+00:04:32,960 --> 00:04:36,660
+الـ internal environment بتكون الاستجابة الأولى للـ
+
+57
+00:04:36,660 --> 00:04:42,050
+nerve tissue طبعا احنا كيف بنتعرف على خصائص أو
+
+58
+00:04:42,050 --> 00:04:45,690
+بنتشخص الأمراض اللي بتصيب الـ tissue عن طريق حاجة
+
+59
+00:04:45,690 --> 00:04:50,070
+اسمها biopsy الـ biopsy هي عبارة عن removal of
+
+60
+00:04:50,070 --> 00:04:54,270
+tissue عشان احنا نعملها بيئة معينة و نشوفها under
+
+61
+00:04:54,270 --> 00:04:58,590
+microscope و ندرس خصائصها و المشكلات اللي ممكن
+
+62
+00:04:58,590 --> 00:05:03,630
+تكون أصبحت موجودة فيها أساس احنا لما بنشخص الـ
+
+63
+00:05:03,630 --> 00:05:06,690
+cancer بناخد الـ biopsy هذه أو بناخد الخزعة ما
+
+64
+00:05:06,690 --> 00:05:11,190
+نسميها بالخزعة و بنحاول بنعملها بنوديها على الـ
+
+65
+00:05:11,190 --> 00:05:15,250
+pathology و هم بيعملوا اللازم و بتعرفوا هل فيها
+
+66
+00:05:15,250 --> 00:05:19,050
+خلايا سرطانية أو لأ مثلا في حالات الـ myopathy
+
+67
+00:05:19,050 --> 00:05:22,190
+بيشوفوا إذا في فعلا existing myopathy أو لأ بناخد
+
+68
+00:05:22,190 --> 00:05:25,610
+خزعة من العضلات و بنروح بنوديها على المختبرات
+
+69
+00:05:25,610 --> 00:05:30,660
+المتقدمة و بيقولوا أن هذا والله الطفل عنده أو
+
+70
+00:05:30,660 --> 00:05:38,440
+ما عندهوش طبعا فيه لها الفحص العادي
+
+71
+00:05:38,440 --> 00:05:41,860
+أو فيه ممكن أننا نأخذ الـ alternative method نأخذ
+
+72
+00:05:41,860 --> 00:05:46,200
+الـ needle نعمل aspiration نحط زي ما احنا بنشوف في
+
+73
+00:05:46,200 --> 00:05:53,350
+الصورة الموجودة أمامنا ممكن أننا ندخل قبرة بإبرة
+
+74
+00:05:53,350 --> 00:05:58,570
+و نسحب من السائل و نقدمه للفحص أو ندخل لداخل
+
+75
+00:05:58,570 --> 00:06:04,950
+القناة بنسميها الـ core بنروح بناخد النواة و بناخد
+
+76
+00:06:04,950 --> 00:06:08,290
+خزعة كبيرة أكبر شوية من الخزعة اللي بناخدها عن
+
+77
+00:06:08,290 --> 00:06:13,920
+طريق الـ needle أو أنه بنفتح فتحة هيك و بنشيل الـ
+
+78
+00:06:13,920 --> 00:06:17,560
+gland أو الـ tissue اللي احنا بدنا اللي صار فيها
+
+79
+00:06:17,560 --> 00:06:24,060
+تغيرات و بناخدها و بنعملها بفحص عند الـ pathology
+
+80
+00:06:24,060 --> 00:06:28,660
+طب إيش الـ function للـ Epithelia الـ tissue طبعا
+
+81
+00:06:28,660 --> 00:06:36,420
+بتشتغل أكثر من من function بتشتغل على لو أخدنا
+
+82
+00:06:36,420 --> 00:06:39,380
+اليوم موضوعنا عن الـ Epithelia
+
+83
+00:06:45,720 --> 00:06:50,480
+ماهي الـ function؟ دعنا نقول واحد بتعملنا حاجة
+
+84
+00:06:50,480 --> 00:06:53,760
+بنسميها protection لأنها covering للـ skin خط
+
+85
+00:06:53,760 --> 00:06:56,760
+الدفاع الأول قلنا عن الجسم هو الـ skin والمكون
+
+86
+00:06:56,760 --> 00:07:00,980
+الأساسي له هي الـ epithelial cell يبقى protection
+
+87
+00:07:03,070 --> 00:07:08,330
+احنا كتير بنتعرض لإنه ممكن إنه يصير فينا abrasions
+
+88
+00:07:08,330 --> 00:07:11,850
+ممكن يصير mechanical compression على الـ skin مين
+
+89
+00:07:11,850 --> 00:07:15,950
+اللي بيحمي الـ skin هذا الـ epithelial cells، كمان
+
+90
+00:07:15,950 --> 00:07:22,310
+ممكن يكون sensory، طب sensory كيف؟ طبعا في خلايا الـ
+
+91
+00:07:22,310 --> 00:07:27,370
+epithelial cell المبطنة مثلا للـ nose بتعطيني إحساس
+
+92
+00:07:27,370 --> 00:07:33,490
+بالـ smell الخلايا المبطنة للسان الـ epithelial cell
+
+93
+00:07:33,490 --> 00:07:38,210
+في اللسان بتخلينا نحس بخاصية اللي هي الـ testing أو
+
+94
+00:07:38,210 --> 00:07:44,230
+التذوق موجودة في الـ inner ear بتخلينا بتساعدنا على
+
+95
+00:07:44,230 --> 00:07:48,750
+التوازن وهكذا هذه المجموعة في الإحساس أحيانا بالـ
+
+96
+00:07:48,750 --> 00:07:52,430
+skin فيها receptors many receptors بتخلينا أننا
+
+97
+00:07:52,430 --> 00:07:57,690
+نشعر أو نحس بالأشياء مواصلات خلينا نقول أو
+
+98
+00:07:57,690 --> 00:08:04,490
+receptors لجهاز العصبي كمان الـ secretion secretion
+
+99
+00:08:05,540 --> 00:08:09,320
+top secretion إيش الإفراز؟ قلنا هذه الخلايا وين
+
+100
+00:08:09,320 --> 00:08:14,910
+موجودة؟ هي مبطنة للقنوات، قلنا هي موجودة في
+
+101
+00:08:14,910 --> 00:08:20,710
+القنوات تبع الجسم القنوات هذه بتبقى عبارة عن
+
+102
+00:08:20,710 --> 00:08:25,890
+إيش؟ قنوات الجهاز مثلا الـ .. الهضمي الهضمي كله
+
+103
+00:08:25,890 --> 00:08:29,250
+بيمر فيها الطعام فهي بتفرز لو اتكلمنا عن القناة
+
+104
+00:08:29,250 --> 00:08:33,950
+الهضمية سواء المعدة سواء الأمعاء فهي بتفرز مواد
+
+105
+00:08:33,950 --> 00:08:38,270
+هاضمة أو عصارات هاضمة هذه وظيفتها بتكون وظيفة
+
+106
+00:08:38,270 --> 00:08:41,950
+الـepithelia السلسلية اللي بتفرز هذه الأشياء وكمان لو
+
+107
+00:08:41,950 --> 00:08:46,080
+اتكلمنا عن الـ intestine مثلا هي الـ intestine فيها
+
+108
+00:08:46,080 --> 00:08:51,420
+خلايا ظهارية بتساعد على الـ secretion وكمان على
+
+109
+00:08:51,420 --> 00:08:56,280
+الامتصاص الامتصاص إيش يعني؟ الامتصاص إنه بتكون دخول
+
+110
+00:08:56,280 --> 00:09:01,120
+الطعام بعد عملية الهضم للقناة للـ intestine بيصير
+
+111
+00:09:01,120 --> 00:09:04,720
+عملية الامتصاص في خلالها من خلالها اللي هي عملية
+
+112
+00:09:04,720 --> 00:09:10,280
+تبادل الأغضية عن طريق الدم excretion كمان كيف بنا
+
+113
+00:09:10,280 --> 00:09:14,660
+نخلص الجسم أو الـ filtration وكيف بنا نخلص الجسم
+
+114
+00:09:14,660 --> 00:09:18,940
+كمان من المواد السامة اللي ممكن مثلا زي الـ kidney
+
+115
+00:09:18,940 --> 00:09:23,380
+و الـ kidney ducts كلها موجود فيها الـ epithelial
+
+116
+00:09:23,380 --> 00:09:26,740
+cell حتى نقدر أو الخلايا اللي موجودة في الجسم اللي
+
+117
+00:09:26,740 --> 00:09:30,140
+هي التعرق احنا نسينا نقول حاجة أن الـ epithelial
+
+118
+00:09:30,140 --> 00:09:37,780
+tissue عبارة عن نوعين بالشكل آه sorry إذا بنقدر
+
+119
+00:09:37,780 --> 00:09:42,820
+نقول في شكل membrane وفي
+
+120
+00:09:42,820 --> 00:09:50,960
+gland حسب تركيبها يعني membrane هذا يعني إنه هذا
+
+121
+00:09:50,960 --> 00:09:56,980
+الشكل في عندنا وهيك في عندنا خلايا وكلها هي
+
+122
+00:09:56,980 --> 00:10:00,300
+عبارة عن compact أو tightly
+
+123
+00:10:03,210 --> 00:10:08,410
+cells جنب بعض جنب بعض جنب بعض كتير قريبة عندنا
+
+124
+00:10:08,410 --> 00:10:12,010
+بنشوف بالرسم الأوضح يمكن أنا مش كتير شاطرة بالرسم
+
+125
+00:10:12,010 --> 00:10:16,970
+هي cells فيها نواة وجنب بعض وفيها basement هنا
+
+126
+00:10:16,970 --> 00:10:21,570
+عندنا هنشوف هذه بتبقى على شكل membrane لكن لو كانت
+
+127
+00:10:21,570 --> 00:10:26,730
+بهذا الشكل فبدها
+
+128
+00:10:26,730 --> 00:10:30,390
+تكون كأنها شكل gland
+
+129
+00:10:37,920 --> 00:10:45,740
+وهنا لنعتبر أن هو موجودة فهنا بدها تكون gland غدة
+
+130
+00:10:45,740 --> 00:10:53,220
+وهنا على شكل من غدد طيب
+
+131
+00:10:53,220 --> 00:10:58,760
+نشوف الـ characteristics إيش مميزاتها أو خصائصها
+
+132
+00:10:58,760 --> 00:11:05,240
+هذه الـ epithelial cells أول شيء أن أنها
+
+133
+00:11:07,130 --> 00:11:12,250
+بتغطي كل أجزاء الـ body بتغطي كل أجزاء الـ body
+
+134
+00:11:12,250 --> 00:11:16,730
+فاحنا بنقول الـ skin هو الـ suit اللي بيبقى لبس الـ
+
+135
+00:11:16,730 --> 00:11:22,050
+body عشان تحمي بتلم كل الأشياء اللي موجودة under
+
+136
+00:11:22,050 --> 00:11:26,390
+the skin فهي covering الـ body و covering الـ organs
+
+137
+00:11:26,390 --> 00:11:27,570
+كمان نفسها
+
+138
+00:11:29,930 --> 00:11:34,390
+من أحد كمان وظيفة احنا قلنا في عندنا عدد من الـ
+
+139
+00:11:34,390 --> 00:11:38,370
+cavities اللي موجودة في الجسم، في عندنا الـ plural
+
+140
+00:11:38,370 --> 00:11:42,210
+cavity و الـ cardiac cavity وعندنا الـ peritoneum
+
+141
+00:11:42,210 --> 00:11:47,370
+اللي موجودة اللي هي في منطقة البطن والأحشاء فهي
+
+142
+00:11:47,370 --> 00:11:53,930
+بتغطيها، بتبطنها كلها وكمان الفتحات الموجودة كلها في
+
+143
+00:11:53,930 --> 00:11:59,890
+الجسم بطبيعتها أو الـ ducts الموجودة في الجسم بتكون
+
+144
+00:11:59,890 --> 00:12:05,050
+مبطنة بالـ epithelial tissue طبعا إذا احنا بنشوف
+
+145
+00:12:05,050 --> 00:12:12,290
+الصورة هنا زي ما هو واضح هي في عندنا basement هنا
+
+146
+00:12:12,290 --> 00:12:20,550
+لها قاعدة وكمان sorry لها قاعدة ولها lateral
+
+147
+00:12:20,550 --> 00:12:24,530
+border اللي احنا شايفينه هنا ولها apical surface
+
+148
+00:12:24,530 --> 00:12:29,050
+يعني لو احنا نضبطها بالصورة كل epithelial cell
+
+149
+00:12:29,050 --> 00:12:34,830
+موجودة في
+
+150
+00:12:34,830 --> 00:12:45,310
+تركيبها بيكون لها قاعدة أو basement وكمان في هنا
+
+151
+00:12:45,310 --> 00:12:47,570
+لو قلنا هذه الخلايا
+
+152
+00:12:49,550 --> 00:12:55,630
+جانب بعضها جانب بعضها مخدش شكل cubic تمام هنا
+
+153
+00:12:55,630 --> 00:13:03,590
+لها free end free end أو apical هنا
+
+154
+00:13:03,590 --> 00:13:06,470
+في لها هذا اسمه lateral
+
+155
+00:13:09,090 --> 00:13:13,070
+border وهنا لتحت بيكون basement إيش وظيفة الـ
+
+156
+00:13:13,070 --> 00:13:16,830
+basement أن أنها بتفصلها عن الـ other underlying
+
+157
+00:13:16,830 --> 00:13:20,510
+connective tissue يعني بتكون شيء مفصولة هي اللي
+
+158
+00:13:20,510 --> 00:13:24,650
+مابتكون على شكل membrane هنا وطبعا هنا فيها النواة
+
+159
+00:13:26,050 --> 00:13:29,710
+زي ما واضح بالرسم اللي على الـ slides شايفين الـ
+
+160
+00:13:29,710 --> 00:13:34,830
+placement اللي هي الطبقة السفلية الـ lateral border
+
+161
+00:13:34,830 --> 00:13:38,790
+أو الـ lateral surface هذا عبارة عن connective
+
+162
+00:13:38,790 --> 00:13:44,370
+tissue بتلاسق لأنها tightly packed tissue فهي
+
+163
+00:13:44,370 --> 00:13:48,330
+متلاسقة ومتراصة فالتلاسق بيصير والترابط عن طريق
+
+164
+00:13:48,330 --> 00:13:52,610
+الـ lateral surface وكمان عندنا الـ free apical end
+
+165
+00:13:52,610 --> 00:13:58,480
+أو surface من مميزاتها أيضًا إنها a-vascular يعني
+
+166
+00:13:58,480 --> 00:14:00,900
+الـ epithelia اللي في الـ cell فيش فيها
+
+167
+00:14:00,900 --> 00:14:08,200
+vascularization على الإطلاق أما فيها إحساس يعني
+
+168
+00:14:08,200 --> 00:14:15,360
+فيها nervous system بيوصلها أما هي also readily
+
+169
+00:14:15,360 --> 00:14:21,770
+divided tightly packed متراصة متلاسقة جدا مع بعضها
+
+170
+00:14:21,770 --> 00:14:29,790
+فيها أحيانا مواد لاصقة desmosomes classified
+
+171
+00:14:29,790 --> 00:14:35,950
+according to its shape and number and number of
+
+172
+00:14:35,950 --> 00:14:41,270
+layers إيش يعني لما بنيجي بنقسم الـ epithelial cell
+
+173
+00:14:41,270 --> 00:14:46,590
+في عندنا نوعين من التقسيمات the classification
+
+174
+00:14:51,260 --> 00:14:59,280
+according to the number of layers أو
+
+175
+00:14:59,280 --> 00:15:09,180
+according to the shape shape
+
+176
+00:15:09,180 --> 00:15:12,180
+فينا ثلاثة أنواع
+
+177
+00:15:15,030 --> 00:15:18,550
+واحد بنسميه الـ Squamous اللي هي عبارة عن إيش
+
+178
+00:15:18,550 --> 00:15:25,050
+شكلها بهذا الشكل هي الـ basement وهيها هيك بيسموها
+
+179
+00:15:25,050 --> 00:15:30,170
+الخرشوفية بتبقى عاملة زي البيضة المقلية بهذا الشكل
+
+180
+00:15:30,170 --> 00:15:32,070
+هذه بنسميها Squamous
+
+181
+00:15:35,030 --> 00:15:41,510
+أما في خلايا ثانية شكلها عامل زي المكعب أنا مش
+
+182
+0
+
+223
+00:19:30,520 --> 00:19:37,660
+تمام؟ وهنا في سل وهنا في عندنا النوى وهنا النوى
+
+224
+00:19:37,660 --> 00:19:44,080
+تمام؟ طيب هذا الشكل اللي إحنا شايفينه صغير وكبير
+
+225
+00:19:44,080 --> 00:19:50,660
+بيبين لي كأنها هي طبقات لكن هي في الحقيقة مش طبقات
+
+226
+00:19:50,660 --> 00:19:56,580
+هي عبارة عن طبقة، خليني بس أورجيكم إياها على ال
+
+227
+00:19:56,580 --> 00:20:01,000
+slide. تقريبا إحنا في الـ slide هذه موجودة
+
+228
+00:20:05,800 --> 00:20:09,440
+هنوصلها عندنا، بلاش إحنا نضيع كتير وقت فيها، هي
+
+229
+00:20:09,440 --> 00:20:15,140
+عبارة قلنا عن إيش؟ عن شكلها، وكأنها طبقية لكن هي
+
+230
+00:20:15,140 --> 00:20:21,180
+بالحقيقة مش طبقات، هي عبارة عن one line لكن فيها سل
+
+231
+00:20:21,180 --> 00:20:23,540
+كبيرة وسل صغيرة
+
+232
+00:20:31,060 --> 00:20:35,520
+يبقى هنا simple stratified، و pseudo كلمة pseudo يعني
+
+233
+00:20:35,520 --> 00:20:42,060
+كاذب، أو بالعربي بتطلع false، يعني pseudo false
+
+234
+00:20:42,060 --> 00:20:51,500
+الـ simple epithelium هي عبارة عن أربعة أنواع simple
+
+235
+00:20:51,500 --> 00:20:58,060
+squamous، شكلها هرشوفية، وطبقة line واحد، simple cuboidal
+
+236
+00:20:58,860 --> 00:21:02,980
+and simple columnar، وفي عندنا الـ pseudostratified
+
+237
+00:21:02,980 --> 00:21:06,060
+وكأن هو بيقول إنها stratified ومش stratified
+
+238
+00:21:06,060 --> 00:21:11,960
+فالحقيقة هي عبارة عن one line أو طبقة واحدة فيها
+
+239
+00:21:11,960 --> 00:21:17,720
+cells طويلة و cells قصيرة متراصة، فبتيجي فبتبدأ
+
+240
+00:21:17,720 --> 00:21:21,820
+المكان الـ wall موجودة فيها، عشان هيك تطلع شكلها و
+
+241
+00:21:21,820 --> 00:21:26,840
+كأنها stratified طبقية أو طبقات الـ epithelial
+
+242
+00:21:26,840 --> 00:21:31,230
+tissue. الـ single squamous epithelial زي ما إحنا
+
+243
+00:21:31,230 --> 00:21:35,230
+شايفينها بهذا الشكل، هي في عندنا الـ basement على
+
+244
+00:21:35,230 --> 00:21:38,350
+طول الـ basement، بيفصل الـ epithelial cell عن الـ
+
+245
+00:21:38,350 --> 00:21:42,110
+connective tissue، وفي نفس الوقت أعطانا الشكل اللي
+
+246
+00:21:42,110 --> 00:21:48,150
+إحنا وصفناه قبل شوية، عبارة عن طبقة واحدة من الـ
+
+247
+00:21:48,150 --> 00:21:49,730
+cells
+
+248
+00:21:57,670 --> 00:22:04,030
+أما الـ simple squamous فهي موجودة وين؟ موجودة في
+
+249
+00:22:04,030 --> 00:22:07,890
+lining الـ blood vessels والـ lymphatic vessels والـ
+
+250
+00:22:07,890 --> 00:22:15,610
+الـ air sacs اللي هي الـ alveoli، single
+
+251
+00:22:15,610 --> 00:22:21,710
+layer of flat cells، فهذه الـ simple squamous cell
+
+252
+00:22:21,710 --> 00:22:24,850
+زي ما إحنا شايفينها بالصورة
+
+253
+00:22:26,300 --> 00:22:30,440
+هي أشكال مختلفة موجودة في أماكن مضبوعة، الموضوع
+
+254
+00:22:30,440 --> 00:22:35,100
+الـ ... بين موجودة simple squamous، فإحنا شايفينها
+
+255
+00:22:35,100 --> 00:22:41,420
+بالرسم، الموضع حوالين
+
+256
+00:22:41,420 --> 00:22:45,100
+الـ peritoneum أو الـ abdominal cavity
+
+257
+00:22:48,360 --> 00:22:53,940
+أما الـ simple cuboid أو cuboidal cell فهذا شكلها
+
+258
+00:22:53,940 --> 00:22:57,100
+عبارة عن طبقة متراصة، هي عندنا الـ connective tissue
+
+259
+00:22:57,100 --> 00:23:01,820
+وعندنا الـ basement، هنا شكل المكعب للخلية، وهنا
+
+260
+00:23:01,820 --> 00:23:03,620
+النوع
+
+261
+00:23:06,580 --> 00:23:10,700
+طبعا إيش وظيفتها؟ موجودة... موجودة في الـ kidney
+
+262
+00:23:10,700 --> 00:23:16,500
+tubes، الـ ovaries، some of the glands، هي عبارة عن
+
+263
+00:23:16,500 --> 00:23:21,860
+simple أو one layer of cube-shaped cells
+
+264
+00:23:24,860 --> 00:23:30,180
+وهذا إحدى الأشكال، هي حاططنا في الـ pancreas كيف
+
+265
+00:23:30,180 --> 00:23:36,560
+شكلها، وكيف بتكون تركبتها، وهي عبارة عن one layer
+
+266
+00:23:36,560 --> 00:23:42,620
+of cuboidal cells، أما
+
+267
+00:23:42,620 --> 00:23:47,440
+الـ columnar فهي زي ما هي موضحة بالشكل، زي ما إحنا
+
+268
+00:23:47,440 --> 00:23:56,110
+شايفين، في عندنا هي basement، وهي في عندنا الـ C، وفي
+
+269
+00:23:56,110 --> 00:24:00,470
+الغالب بيكون فيه سيليا أو أهداب موجودة، أو زغب ما
+
+270
+00:24:00,470 --> 00:24:03,910
+نسميه إحنا الزغب، يبقى بقى a single layer of
+
+271
+00:24:03,910 --> 00:24:08,290
+elongated cells، للـ nuclei usually near the
+
+272
+00:24:08,290 --> 00:24:12,950
+basement، عادة بتكون قريبة من الـ basement of the
+
+273
+00:24:12,950 --> 00:24:17,770
+membrane، sometimes بتكون في عندها في نهاياتها حاجة
+
+274
+00:24:17,770 --> 00:24:21,710
+اسمها السيليا، ما بنسميها إحنا الأهداب، وكمان ممكن
+
+275
+00:24:21,710 --> 00:24:24,890
+يكون حاجة اسمها الـ microvilli، الزغب اللي إحنا
+
+276
+00:24:24,890 --> 00:24:29,010
+بنتكلم عنه، بنقول عنه الزغب، إن هي شعيرات صغيرة كتير
+
+277
+00:24:29,370 --> 00:24:33,670
+often have goblet cells، زي عاملة بعض الـ cells
+
+278
+00:24:33,670 --> 00:24:38,250
+اللي عاملة زي جيوب أو زي الكؤوس، خلينا نسميها
+
+279
+00:24:38,250 --> 00:24:43,110
+موجودة في الـ ureters والـ stomach والـ intestine
+
+280
+00:24:43,110 --> 00:24:50,710
+وهذا شكلها، كيف بتكون موجودة بالخلية، وإذا إحنا
+
+281
+00:24:50,710 --> 00:24:57,250
+بتطلعنا على الـ goblet cells اللي موجودة بهذا المكان
+
+282
+00:25:02,550 --> 00:25:07,610
+الـ simple columnar والـ cilia هي إحنا شايفينها زي
+
+283
+00:25:07,610 --> 00:25:17,450
+موجودة في القناة uterine أو في الـ uterine tubes أو في
+
+284
+00:25:17,450 --> 00:25:22,670
+الـ fallopian tubes، هذا
+
+285
+00:25:22,670 --> 00:25:27,510
+له علاقة بموضوع التطبيق وخروج البويضة واستقطاب
+
+286
+00:25:27,510 --> 00:25:32,030
+الحيوان المنوي، نقولها كده عشان هي بتساعدها السيليا
+
+287
+00:25:36,230 --> 00:25:42,510
+أما الـ pseudostratified ciliated epithelium هي
+
+288
+00:25:42,510 --> 00:25:47,250
+عبارة عن single layer of elongated cells، سل طويلة زي ما
+
+289
+00:25:47,250 --> 00:25:52,410
+إحنا وضحناها بالرسم، وكمان موجود فيها نواة بس مش
+
+290
+00:25:52,410 --> 00:25:58,920
+على نفس المستوى، ممكن تكون الـ nuclei في الـ base and
+
+291
+00:25:58,920 --> 00:26:05,900
+above، pseudostratified، تطلع فيها فكرتها stratified دائما
+
+292
+00:26:05,900 --> 00:26:09,360
+أو غالبا تكون فيها السيليا اللي هي الأهداب، والـ
+
+293
+00:26:09,360 --> 00:26:13,650
+goblet cells، تقريبا بتكون موجودة في الـ respiratory
+
+294
+00:26:13,650 --> 00:26:17,510
+pathway، إحنا بنفهم إن وجود السيليا عشان تساعد على
+
+295
+00:26:17,510 --> 00:26:21,970
+عملية الـ expectoration اللي ممكن تساعد على خروج الـ
+
+296
+00:26:21,970 --> 00:26:25,950
+mucus أو الـ excessive mucus أو الـ unwanted mucus
+
+297
+00:26:25,950 --> 00:26:29,030
+اللي موجود في الـ respiratory tract
+
+298
+00:26:32,980 --> 00:26:37,100
+وهذا الشرح التاني بيوضح، موجود الـ pseudo
+
+299
+00:26:37,100 --> 00:26:41,800
+stratified epithelia، موجود في التراكيا لأنه دائما
+
+300
+00:26:41,800 --> 00:26:44,200
+بيحتوي على الأهداب اللي بتساعد على عملية الـ
+
+301
+00:26:44,200 --> 00:26:49,560
+expectoration. أما الـ stratified اللي إحنا بنسميها
+
+302
+00:26:49,560 --> 00:26:53,840
+الطبقية أو المجموعة، يعني according to the
+
+303
+00:26:53,840 --> 00:26:56,300
+classification، according to the number of layers
+
+304
+00:26:56,300 --> 00:27:01,320
+of layers، فعندنا الـ stratified squamous والـ stratified
+
+305
+00:27:01,320 --> 00:27:06,960
+cuboidal وعندنا الـ stratified columnar، يعني نفس أنواع
+
+306
+00:27:06,960 --> 00:27:13,800
+الخلايا لكن مكونة من عدة طبقات، وهذا
+
+307
+00:27:16,080 --> 00:27:20,860
+مظهر أو خلينا نقول رسم توضيحي، stratified
+
+308
+00:27:20,860 --> 00:27:25,520
+squamous اللي هي الحرشفية لكن الطبقية، many layers of cells,
+
+309
+00:27:25,520 --> 00:27:29,300
+the top cells are flat، لأن إحنا عادة لما
+
+310
+00:27:29,300 --> 00:27:32,440
+بنسميها بنسميها بالطبقة الأخيرة، ما بننظر للطبقات
+
+311
+00:27:32,440 --> 00:27:36,680
+التانية، في الطبقة الأخيرة الشكل، فبنسمي الـ layer هذا
+
+312
+00:27:36,680 --> 00:27:41,980
+الشكل، the top cells are flat، can accumulate keratin، إيش
+
+313
+00:27:41,980 --> 00:27:46,550
+يعني keratin؟ فيه protein في الجسم اسمه keratin، هذا
+
+314
+00:27:46,550 --> 00:27:53,030
+في خلايا لكن ميتة أو خلايا ما فيهاش نواة، هذه
+
+315
+00:27:53,030 --> 00:27:59,230
+بتكون الـ outer layer of the skin، وكمان الـ oral
+
+316
+00:27:59,230 --> 00:28:03,470
+cavity والـ vagina والـ anal canal، طبعا هذه
+
+317
+00:28:03,470 --> 00:28:07,230
+وظيفتها، الخلايا اللي فيها الكيراتين بتساعد على
+
+318
+00:28:07,230 --> 00:28:11,690
+shock absorption، بتساعد على الـ ... هذه بنسميها إحنا
+
+319
+00:28:11,690 --> 00:28:16,670
+خلايا ميتة بتخفف الصدمات على الـ skin أو على
+
+320
+00:28:16,670 --> 00:28:18,130
+الأماكن هذه
+
+321
+00:28:22,970 --> 00:28:27,070
+هذا شكل من الـ stratified squamous موجود في الـ
+
+322
+00:28:27,070 --> 00:28:33,490
+vagina، أما
+
+323
+00:28:33,490 --> 00:28:38,070
+الـ cuboidal، two to three layers of cube-shaped cells
+
+324
+00:28:38,070 --> 00:28:41,330
+line the ducts of mammary glands، الممرات اللي هي
+
+325
+00:28:41,330 --> 00:28:46,010
+خلايا الثدي، sweat glands، salivary glands اللي
+
+326
+00:28:46,010 --> 00:28:50,180
+هي بتفرز اللعاب، وكذلك الـ pancreas، زي ما إحنا
+
+327
+00:28:50,180 --> 00:28:55,340
+شايفينها بالصورة، مجموعة من الـ cubic أو الـ
+
+328
+00:28:55,340 --> 00:29:00,400
+cuboidal cells لكن أكثر من طبقة، وطبعا هذا عادة
+
+329
+00:29:00,400 --> 00:29:04,280
+الرسم بيبين وبيزيد بإن في عندنا الـ basement اللي
+
+330
+00:29:04,280 --> 00:29:07,940
+بيفصل الـ connective tissue عن الـ cells، وشايفين
+
+331
+00:29:07,940 --> 00:29:11,960
+الـ end هنا، الـ apical surface هنا، وفي كمان في الـ
+
+332
+00:29:11,960 --> 00:29:15,360
+borders هذه أو الـ lateral borders اللي بيكون
+
+333
+00:29:15,360 --> 00:29:20,340
+بيحتوي على المواد اللاصقة اللي بتخليها tightly
+
+334
+00:29:20,340 --> 00:29:27,000
+closed أو packed tissue، في
+
+335
+00:29:27,000 --> 00:29:31,860
+عندنا الـ stratified cuboidal epithelium اللي
+
+336
+00:29:31,860 --> 00:29:38,430
+موجودة في الـ oesophagus، وهذا شكلها، أما الـ columnar
+
+337
+00:29:38,430 --> 00:29:43,490
+فهي عبارة عن stratified columnar، بنفس الطريقة اللي
+
+338
+00:29:43,490 --> 00:29:47,010
+إحنا بنتكلم عنها، إن هي عبارة عن مجموعة من الطبقات
+
+339
+00:29:47,010 --> 00:29:49,650
+إحنا بنطلع على الطبقة الأخيرة، زي ما إحنا شايفين
+
+340
+00:29:49,650 --> 00:29:54,790
+كيف شكل الطبقة الأخيرة، فهي شكلها طولي أو عمودي
+
+341
+00:29:54,790 --> 00:29:58,710
+فبنسميها stratified columnar
+
+342
+00:30:01,090 --> 00:30:05,410
+بتكون الطبقة الخارجية مخدة شكل الـ column، أما
+
+343
+00:30:05,410 --> 00:30:09,570
+الطبقات التانية مخدة شكل look like the pipeline part
+
+344
+00:30:09,570 --> 00:30:17,870
+of male urethra and part of pharynx، وهذا رسم
+
+345
+00:30:17,870 --> 00:30:23,630
+توضيحي، في حاجة اسمها transitional epithelium،
+
+346
+00:30:23,630 --> 00:30:31,200
+الـ transitional هذه، ليش اتسمت هيك؟ Transitional لأنها
+
+347
+00:30:31,200 --> 00:30:38,540
+many cell layers, cubic shaped and elongated cells
+
+348
+00:30:38,540 --> 00:30:43,440
+هذه ليش اتسمت هيك؟ نتكلم عن إحنا مثلا عن الـ bladder،
+
+349
+00:30:43,440 --> 00:30:47,080
+الـ bladder بتحتوي على الـ urine، الـ bladder لما بيكون فش
+
+350
+00:30:47,080 --> 00:30:51,380
+فيه urine بتكون صغيرة طبعا، فبيكون شكل الـ cell
+
+351
+00:30:51,380 --> 00:30:55,560
+فيها columnar بهذا الشكل
+
+352
+00:31:15,400 --> 00:31:21,340
+تمام؟ تمام؟ تمام؟
+
+353
+00:31:21,340 --> 00:31:24,780
+تمام؟ تمام؟ تمام؟
+
+354
+00:31:41,530 --> 00:31:48,050
+تخيلوا شغالة لما بتنشد بتنشد زي الـ bladder، الـ
+
+355
+00:31:48,050 --> 00:31:51,270
+bladder لما تكون full of urine بتنشد، فبيصير شكل
+
+356
+00:31:51,270 --> 00:31:56,230
+الخلايا فيها كده cubic، تمام، لما بيروح الضغط بيصير
+
+357
+00:31:56,230 --> 00:32:04,210
+شكلها عمودي، فهي بتحتوي على هذا النوع من الـ cells
+
+358
+00:32:04,210 --> 00:32:08,330
+lining الـ bladder والـ urethra، and ureter
+
+359
+00:32:22,500 --> 00:32:28,440
+أما الـ glandular epithelium، composed of cells that
+
+360
+00:32:28,440 --> 00:32:33,320
+are specialized to produce and secrete substances، يبقى
+
+361
+00:32:33,320 --> 00:32:39,040
+إحنا في عندنا secretion وكمان بيبقى production للـ
+
+362
+00:32:39,040 --> 00:32:46,260
+الـ hormones، زي الـ endocrine glands، وفي عندنا الـ
+
+363
+00:32:46,260 --> 00:32:52,080
+exocrine glands، الـ endocrine ما فيهاش ducts
+
+364
+00:32:54,470 --> 00:32:58,650
+and secrete their product directly into the
+
+365
+00:32:58,650 --> 00:33:02,250
+interstitial fluid and bloodstream، لأن هي عبارة
+
+366
+00:33:02,250 --> 00:33:06,850
+عن hormones داخلية، endocrine داخلية، نتكلم عن الـ
+
+367
+00:33:06,850 --> 00:33:11,090
+exocrine اللي هي الخارجية، هذه ليش lack of ducts؟
+
+368
+00:33:11,090 --> 00:33:14,490
+ما فيهاش قنوات لأن هي بتفرز في bloodstream
+
+369
+00:33:14,490 --> 00:33:19,030
+مباشرة، وبتفرز في الـ interstitial fluid مباشرة، فهي
+
+370
+00:33:19,030 --> 00:33:25,440
+ما فيهاش ducts، طيب الـ hormones عبارة عن إيه؟
+
+371
+00:33:25,440 --> 00:33:28,860
+هي عبارة عن مواد كيميائية بتفرزها... بتفرزها...
+
+372
+00:33:28,860 --> 00:33:33,560
+بتفرزها هذه الـ glands حتى تنظم الجسم، تعمل حالة من
+
+373
+00:33:33,560 --> 00:33:38,120
+الـ homeostasis، تضامن الجسم أو توازن الجسم، التوازن
+
+374
+00:33:38,120 --> 00:33:41,880
+الداخلي والخارجي، هذا الـ ... الـ ... الـ ... الـ
+
+375
+00:33:41,880 --> 00:33:45,550
+endocrine and exocrine systems بالضبط، خلينا نقول أو الـ
+
+376
+00:33:45,550 --> 00:33:48,970
+endocrine system هو اللي بيتحكم فيه، فالـ hormones
+
+377
+00:33:48,970 --> 00:33:52,950
+عبارة عن إيه؟ chemical messengers to influence
+
+378
+00:33:52,950 --> 00:33:56,930
+cell activity elsewhere in the body، يعني ممكن هي
+
+379
+00:33:56,930 --> 00:34:01,910
+بتفرز من مكان لكن بتكون تأثيرها في أماكن تانية على
+
+380
+00:34:01,910 --> 00:34:05,270
+الجسم، عشان هي بتفرز في bloodstream نفسه، في الـ
+
+381
+00:34:05,270 --> 00:34:09,330
+interstitial fluid، أما الـ exocrine هي آخر
+
+382
+00:34:11,570 --> 00:34:14,510
+محاضرتنا لليوم، مش هنطول عليكم، الـ
+
+383
+00:34:14,510 --> 00:34:17,890
+exocrine اللي هو الإفراز الخارجي، maintain their
+
+384
+00:34:17,890 --> 00:34:21,430
+contact with the epithelial surface by means of
+
+385
+00:34:21,430 --> 00:34:24,730
+ducts، يعني الـ exocrine فيها ducts، أما الـ endocrine
+
+386
+00:34:24,730 --> 00:34:27,670
+ما فيهاش ducts، لأنها بتفرز في bloodstream نفسه،
+
+387
+00:34:27,670 --> 00:34:35,130
+وهذه بتروح عن طريق قنوات عشان تطلعها للخارج، secretes
+
+388
+00:34:35,130 --> 00:34:38,870
+materials onto the surface of the skin or onto the
+
+389
+00:34:38,870 --> 00:34:44,710
+epithelial surface lining internal passageways
+
+390
+00:34:45,920 --> 00:34:49,080
+ننهي محاضرتنا لليوم، عشان الأسبوع اللي جاي إن شاء
+
+391
+00:34:49,080 --> 00:34:52,420
+الله يكون، أو يوم الإثنين، الأسبوع هذا إن شاء الله
+
+392
+00:34:52,420 --> 00:34:56,320
+يكون محاضرة عن باقي الـ classifications بتاعة الـ
+
+393
+00:34:56,320 --> 00:34:59,760
+tissues، الـ connective tissue والـ muscle tissue والـ
+
+394
+00:34:59,760 --> 00:35:04,240
+nervous tissue، ويعطيكم العافية، والسلام عليكم
+
+395
+00:35:04,240 --> 00:35:05,060
+ورحمة الله
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..83495a1cab8b7685e86782b53db0c73ce5749568
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s_postprocess.srt
@@ -0,0 +1,1580 @@
+1
+00:00:05,110 --> 00:00:09,450
+بسم الله الرحمن الرحيم حضرتنا التالتة في مساق ال
+
+2
+00:00:09,450 --> 00:00:12,770
+anatomy هنتكلم فيها عن ال tissue level
+
+3
+00:00:12,770 --> 00:00:18,990
+organization موضوعنا اليوم أنواع ال tissue طبعا زي
+
+4
+00:00:18,990 --> 00:00:23,250
+ما احنا عارفين ان مجموعة ال cells قولنا المكون
+
+5
+00:00:23,250 --> 00:00:28,750
+الأساسي هي ال cell مجموعة من ال cells بتعملنا
+
+6
+00:00:28,750 --> 00:00:33,250
+tissue مجموعة من ال tissue بتعمل organ
+
+7
+00:00:37,360 --> 00:00:43,060
+تمام؟ ومجموعة من ال organs بتعملنا
+
+8
+00:00:43,060 --> 00:00:47,600
+ال system و بعدين ال system بيعمل ال body فاحنا من
+
+9
+00:00:47,600 --> 00:00:54,600
+هان لهان اليوم هنتكلم أنواع ال type of tissue
+
+10
+00:00:56,780 --> 00:01:00,680
+طبعا في عندنا four main types of tissue طبعا قولنا
+
+11
+00:01:00,680 --> 00:01:04,140
+مجموعة من ال cells المتشابهه بتكون ليه؟ ال tissue
+
+12
+00:01:04,140 --> 00:01:09,260
+بتكون from common embryologic origin and have the
+
+13
+00:01:09,260 --> 00:01:14,900
+same function طبعا هذا العلم اللي بيدرس ال tissue
+
+14
+00:01:14,900 --> 00:01:19,280
+هو علم بنسميه احنا علم الhistology طبعا عندنا four
+
+15
+00:01:19,280 --> 00:01:25,400
+types of tissue عندنا ال epithelial
+
+16
+00:01:30,740 --> 00:01:37,160
+وعنا ال connective tissue وعنا
+
+17
+00:01:37,160 --> 00:01:44,690
+ال muscle tissue وعنا ال nerve tissueطبعا أربعة
+
+18
+00:01:44,690 --> 00:01:50,890
+type من ال tissue هو مكون لأو خلينا نقول أنواع ال
+
+19
+00:01:50,890 --> 00:01:54,270
+tissue اللي موجودة في الجسم اليوم تركزنا في
+
+20
+00:01:54,270 --> 00:01:59,150
+محاضرتنا على ال epithelial tissue و أنواعها و
+
+21
+00:01:59,150 --> 00:02:03,650
+تركبتها و كيف احنا ممكن نتعرف على الوظيفة اللي هي
+
+22
+00:02:03,650 --> 00:02:04,830
+بتقدمها
+
+23
+00:02:06,860 --> 00:02:11,480
+الـ Epithelial tissue طبيعتها هي مسموها الخلايا
+
+24
+00:02:11,480 --> 00:02:16,840
+الطلاقية موجودة تقريبا في كل أعضاء الجسم اللي هو
+
+25
+00:02:16,840 --> 00:02:22,560
+ضائف متعددة موجودة على ال surface of the skinكمان
+
+26
+00:02:22,560 --> 00:02:26,680
+موجودة على كل الأماكن التجاوف إذا بنتذكر في محاضرة
+
+27
+00:02:26,680 --> 00:02:30,660
+ال Anatomy الأولى قلنا فيه أن التجاوف الموجودة أو
+
+28
+00:02:30,660 --> 00:02:33,880
+ال cavities اللي موجودة فهي مبطنة لكل ال cavities
+
+29
+00:02:33,880 --> 00:02:38,120
+الموجودة في الجسم اللي هي ال pleural cavity، ال
+
+30
+00:02:38,120 --> 00:02:42,260
+cardiac، ال peritoneum، ال abdominal cavitiesكمان
+
+31
+00:02:42,260 --> 00:02:45,540
+موجودة في الـ ducts في كل القنوات اللي موجودة في
+
+32
+00:02:45,540 --> 00:02:50,540
+الجسم و بتكون مع بعض ال glands يبقى هي ال
+
+33
+00:02:50,540 --> 00:02:54,780
+epithelial cells هنتعرف على وظيفتها لما نبدأ فيها
+
+34
+00:02:54,780 --> 00:02:57,080
+لكن نروح على ال connective tissue ال connective
+
+35
+00:02:57,080 --> 00:03:00,240
+tissue الخلايا الضامة بيسموها الخلايا اللي بتربط
+
+36
+00:03:00,240 --> 00:03:06,860
+الأشياء مع بعضها في الجسم طبعا بتساعد و بتدعم ال
+
+37
+00:03:06,860 --> 00:03:11,830
+structure سبعة الجسمall together and store energy
+
+38
+00:03:11,830 --> 00:03:18,050
+and كمان provide immune system طبعا ال muscle
+
+39
+00:03:18,050 --> 00:03:22,190
+tissue ال muscle tissue هي عبارة عن الخلية المكونة
+
+40
+00:03:22,190 --> 00:03:27,090
+للعضلات العضلات بما فيها ال muscle نفسها و ال
+
+41
+00:03:27,090 --> 00:03:30,260
+tendon و كل ال connective tissuesاللي حواليها لكن
+
+42
+00:03:30,260 --> 00:03:34,140
+احنا نتكلم عن العضلة العضلة هي نسيج خاص اما ال
+
+43
+00:03:34,140 --> 00:03:40,200
+nerve tissue فهي العضلة المكونة لجهاز ال sorry ال
+
+44
+00:03:40,200 --> 00:03:45,500
+tissue المكونة لجهاز ال nervous system طبيعتها
+
+45
+00:03:47,010 --> 00:03:53,170
+بتقدم عندنا ال electricity نعرفين أن الجسم عبارة
+
+46
+00:03:53,170 --> 00:03:57,590
+عن مواصلات بتوصل ال orderات من الدماغ ال spinal
+
+47
+00:03:57,590 --> 00:04:03,290
+cord ل الأطراف لجميع أجزاء الجسم فهي بتعملنا ال
+
+48
+00:04:03,290 --> 00:04:06,830
+electrical signal detected change طبعا احنا لو
+
+49
+00:04:06,830 --> 00:04:10,910
+احنا طلعنا في جو بارد أو دخلنا على جو سخن كيف
+
+50
+00:04:10,910 --> 00:04:14,350
+جسمنا بتلقى هذه الإشارة بتلقها عن طريق ال nerve
+
+51
+00:04:14,350 --> 00:04:18,240
+tissueو ال nerve cell نفسها كمان respond to
+
+52
+00:04:18,240 --> 00:04:22,480
+nervous impulses أي impulse بتيجي زواء عن طريق ال
+
+53
+00:04:22,480 --> 00:04:25,340
+reflex مدينا ايدنا مسكنا حاجة ساخنة على طول احنا
+
+54
+00:04:25,340 --> 00:04:29,100
+بنرميها دعزنا على مسمارة على طول بنبعد عنه أي
+
+55
+00:04:29,100 --> 00:04:32,960
+مشكلة ممكن تواجهنا مع ال external environment أو
+
+56
+00:04:32,960 --> 00:04:36,660
+ال internal environment بتكون الاستجابة الأولى لل
+
+57
+00:04:36,660 --> 00:04:42,050
+nerve tissueطبعا احنا كيف بنتعرف على خصائص أو
+
+58
+00:04:42,050 --> 00:04:45,690
+بنتشخص الأمراض اللي بتصيب ال tissue عن طريق حاجة
+
+59
+00:04:45,690 --> 00:04:50,070
+اسمها biopsy ال biopsy هي عبارة عن removal of
+
+60
+00:04:50,070 --> 00:04:54,270
+tissue عشان احنا نعملها بيئة معينة و نشوفها under
+
+61
+00:04:54,270 --> 00:04:58,590
+microscope و ندرس خصائصها و المشكلات اللي ممكن
+
+62
+00:04:58,590 --> 00:05:03,630
+تكون أصبحت موجودة فيهاأساس احنا لما بنشخص ال
+
+63
+00:05:03,630 --> 00:05:06,690
+cancer بناخد ال biopsy هذه او بناخد الخزعة ما
+
+64
+00:05:06,690 --> 00:05:11,190
+نسميه بالخزعة و بنحاول بنعملها بنوديها على ال
+
+65
+00:05:11,190 --> 00:05:15,250
+pathology و هم بيعملوها اللازم و بتعرفوا هل فيها
+
+66
+00:05:15,250 --> 00:05:19,050
+خلايا سرطانية او لأ مثلا في حالات ال myopathy
+
+67
+00:05:19,050 --> 00:05:22,190
+بيشوفوا اذا في فعلا existing myopathy ولا لأ بناخد
+
+68
+00:05:22,190 --> 00:05:25,610
+خزعة من العضلات و بنروح بنوديها على المختبرات
+
+69
+00:05:25,610 --> 00:05:30,660
+المتقدمة و بيقولوا ان هذا والله الطفل عندهما يبثي
+
+70
+00:05:30,660 --> 00:05:38,440
+أو ما عندهوش ما يبثي طبعا فيه لها الفزعة العادية
+
+71
+00:05:38,440 --> 00:05:41,860
+أو فيه ممكن أننا ناخد ال alternative method ناخد
+
+72
+00:05:41,860 --> 00:05:46,200
+ال needle نعمل aspiration نحط زي ما احنا بنشوف في
+
+73
+00:05:46,200 --> 00:05:53,350
+الصورة الموجودة أمامنا ممكن أننا ندخل قبرة هنانيدل
+
+74
+00:05:53,350 --> 00:05:58,570
+و نسحب من السائل و نقدمه للفحص أو ندخل لداخل
+
+75
+00:05:58,570 --> 00:06:04,950
+القناة بنسموها ال core بنروح بناخد النواة و بناخد
+
+76
+00:06:04,950 --> 00:06:08,290
+خزعة كبيرة أكبر شوية من الخزعة اللي بناخدها عن
+
+77
+00:06:08,290 --> 00:06:13,920
+طريق ال needle أو أنه بنفتح فتحة هيك و بتنشلكل الـ
+
+78
+00:06:13,920 --> 00:06:17,560
+gland أو ال tissue اللى احنا بدنا اللى صار فيها
+
+79
+00:06:17,560 --> 00:06:24,060
+تغيرات و بناخدها و بنعملها بفحص عند ال pathology
+
+80
+00:06:24,060 --> 00:06:28,660
+طب إيش ال function لل Epithelia ال tissue طبعا
+
+81
+00:06:28,660 --> 00:06:36,420
+بتشتغل أكتر من من function بتشتغل على لو أخدنا
+
+82
+00:06:36,420 --> 00:06:39,380
+اليوم موضوعنا عن ال Epithelia
+
+83
+00:06:45,720 --> 00:06:50,480
+ماهي ال function؟ دعنا نقول واحد بتعملنا حاجة
+
+84
+00:06:50,480 --> 00:06:53,760
+بنسميها protection لأنها covering لل skin خط
+
+85
+00:06:53,760 --> 00:06:56,760
+الدفاع الأول قلنا عن الجسم هو ال skin والمكون
+
+86
+00:06:56,760 --> 00:07:00,980
+الأساسي له هي ال epithelial cell يبقى protection
+
+87
+00:07:03,070 --> 00:07:08,330
+احنا كتير بنتعرض لإنه ممكن إنه يصير فينا abrasions
+
+88
+00:07:08,330 --> 00:07:11,850
+ممكن يصير mechanical compression على ال skin مين
+
+89
+00:07:11,850 --> 00:07:15,950
+اللي بيحمي ال skin هذا ال epithelial cells، كمان
+
+90
+00:07:15,950 --> 00:07:22,310
+ممكن يكون sensory، طب sensory كيف؟طبعا في خلايا ال
+
+91
+00:07:22,310 --> 00:07:27,370
+epithelial cell المبطنة مثلا لل nos بتعطيني إحساس
+
+92
+00:07:27,370 --> 00:07:33,490
+بال smell الخلايا المبطنة للسان ال epithelial cell
+
+93
+00:07:33,490 --> 00:07:38,210
+في اللسان بتخلينا نحس بخاصية اللي هي ال testing أو
+
+94
+00:07:38,210 --> 00:07:44,230
+التدوقموجودة في ال inner ear بتخلينا بتساعدنا على
+
+95
+00:07:44,230 --> 00:07:48,750
+التوازن و هكذا هذه المجموعة في الإحساس أحيانا بال
+
+96
+00:07:48,750 --> 00:07:52,430
+skin فيها receptors many receptors بتخلينا أننا
+
+97
+00:07:52,430 --> 00:07:57,690
+نشعر أو نحس بالأشياء مواصلات خلينا فيها تقول أو
+
+98
+00:07:57,690 --> 00:08:04,490
+receptors لجهاز العصبي كمان ال secretion secretion
+
+99
+00:08:05,540 --> 00:08:09,320
+top secretion إيش الإفراز؟ قولنا هذه الخلايا وين
+
+100
+00:08:09,320 --> 00:08:14,910
+موجودة؟ هي مبطنة للقنوات، قولنا هي موجودةفي
+
+101
+00:08:14,910 --> 00:08:20,710
+القنوات تبع الجسم القنوات هذه بتبقى على عبارة عن
+
+102
+00:08:20,710 --> 00:08:25,890
+إيش؟ قنوات الجهاز مثلا ال .. الهضمي الهضمي كله
+
+103
+00:08:25,890 --> 00:08:29,250
+بيمر فيها الطعام فهي بتفرز لو اتكلمنا عن القناة
+
+104
+00:08:29,250 --> 00:08:33,950
+الهضمية سواء المعدة سواء الأمعاء فهي بتفرز مواد
+
+105
+00:08:33,950 --> 00:08:38,270
+هاضمة أو عصارات هاضمة هذه وظيفتها بتكون وظيفة
+
+106
+00:08:38,270 --> 00:08:41,950
+الectelia السلسلية اللى تفرز هذه الأشياء وكمان لو
+
+107
+00:08:41,950 --> 00:08:46,080
+اتكلمنا عن ال intestine مثلاهي ال intestine فيها
+
+108
+00:08:46,080 --> 00:08:51,420
+خلايا بثيل يلسل بتساعد على ال secretion وكمان على
+
+109
+00:08:51,420 --> 00:08:56,280
+الانتصاص الانتصاص إيش يعني؟ الانتصاص إنه بتكون دخل
+
+110
+00:08:56,280 --> 00:09:01,120
+الطعام بعد عملية الهضم للقناع لل intestine بيصير
+
+111
+00:09:01,120 --> 00:09:04,720
+عملية الانتصاص في خلالها من خلالها اللي هي عملية
+
+112
+00:09:04,720 --> 00:09:10,280
+تبادل الأغضية عن طريق الدمexecration كمان كيف بنا
+
+113
+00:09:10,280 --> 00:09:14,660
+نخلص الجسم أو ال filtration وكيف بنا نخلص الجسم
+
+114
+00:09:14,660 --> 00:09:18,940
+كمان من المواد السامة اللي ممكن مثلا زي ال kidney
+
+115
+00:09:18,940 --> 00:09:23,380
+و ال kidney ducts كلها موجود فيها ال epithelial
+
+116
+00:09:23,380 --> 00:09:26,740
+cell حتى نقدر أو الخلايا اللي موجودة في الجسم اللي
+
+117
+00:09:26,740 --> 00:09:30,140
+هي التعرق احنا انسينا نقول حاجة ان ال epithelial
+
+118
+00:09:30,140 --> 00:09:37,780
+tissue عبارة عن نوعين بالشكل اه sorryإذا بنقدر
+
+119
+00:09:37,780 --> 00:09:42,820
+نقول في شكل membrane وفي
+
+120
+00:09:42,820 --> 00:09:50,960
+gland حسب تركبتها يعني membrane هذا يعني إنه هذا
+
+121
+00:09:50,960 --> 00:09:56,980
+الشكل في عندنا و هيك في عندنا خلايا و كلها هي
+
+122
+00:09:56,980 --> 00:10:00,300
+عبارة عن compact أو tightly
+
+123
+00:10:03,210 --> 00:10:08,410
+cells جنب بعض جنب بعض جنب بعض كتير قريبا عندنا
+
+124
+00:10:08,410 --> 00:10:12,010
+بنشوف بالرسم الأوضح يمكن أنا مش كتير شاطرة بالرسم
+
+125
+00:10:12,010 --> 00:10:16,970
+هي cells فيها نوا وجنب بعض وفيها basement هنا
+
+126
+00:10:16,970 --> 00:10:21,570
+عندنا هنشوف هذه بتبقى على شكل membrane لكن لو كانت
+
+127
+00:10:21,570 --> 00:10:26,730
+بهذا الشكل فبدها
+
+128
+00:10:26,730 --> 00:10:30,390
+تكون كأنها شكل glance
+
+129
+00:10:37,920 --> 00:10:45,740
+وهنا لنعتبر ان هو موجودة فهنا بدها تكون gland غداد
+
+130
+00:10:45,740 --> 00:10:53,220
+وهنا على شكل من brains طيب
+
+131
+00:10:53,220 --> 00:10:58,760
+نشوف ال characteristics ايش مميزاتها او خصائصها
+
+132
+00:10:58,760 --> 00:11:05,240
+هذه ال epithelial cells اول اشي انها
+
+133
+00:11:07,130 --> 00:11:12,250
+بتغطي كل أجزاء ال body بتغطي كل أجزاء ال body
+
+134
+00:11:12,250 --> 00:11:16,730
+فاحنا بنقول ال skin هو ال suit اللي بيبقى لبسها ال
+
+135
+00:11:16,730 --> 00:11:22,050
+body عشان تحمي بتلم كل الأشياء اللي موجودة under
+
+136
+00:11:22,050 --> 00:11:26,390
+the skin فهي covering ال body و covering ال organs
+
+137
+00:11:26,390 --> 00:11:27,570
+كمان نفسها
+
+138
+00:11:29,930 --> 00:11:34,390
+من أحد كمان وظيفة احنا قلنا في عندنا عدد من ال
+
+139
+00:11:34,390 --> 00:11:38,370
+cavities اللي موجودة في الجسم، في عندنا ال plural
+
+140
+00:11:38,370 --> 00:11:42,210
+cavity و ال cardiac cavity و عندنا الberitanium
+
+141
+00:11:42,210 --> 00:11:47,370
+اللي موجودة اللي هي في منطقة البطن و الأحشاء فهي
+
+142
+00:11:47,370 --> 00:11:53,930
+بتغطيها، بتبطمها كلهاوكمان الفتحات موجودة كلها في
+
+143
+00:11:53,930 --> 00:11:59,890
+الجسم بطبيعتها او ال ducts الموجودة في الجسم بتكون
+
+144
+00:11:59,890 --> 00:12:05,050
+مبطنة بال epithelial tissue طبعا إذا احنا بنشوف
+
+145
+00:12:05,050 --> 00:12:12,290
+الصورة هنا زي ما هو واضح هي في عندنا basement هنا
+
+146
+00:12:12,290 --> 00:12:20,550
+إلها قاعدة وكمان sorry إلها قاعدةوالها lateral
+
+147
+00:12:20,550 --> 00:12:24,530
+border اللي احنا شايفينه هنا والها apical surface
+
+148
+00:12:24,530 --> 00:12:29,050
+يعني لو احنا نضبحها بالصورة كل epithelial cell
+
+149
+00:12:29,050 --> 00:12:34,830
+موجودة في
+
+150
+00:12:34,830 --> 00:12:45,310
+تركبتها بيكون لها قاعدة أو basement وكمان في هنا
+
+151
+00:12:45,310 --> 00:12:47,570
+لو قلنا هذه الخلايا
+
+152
+00:12:49,550 --> 00:12:55,630
+جانب بعضها جانب بعضها مخدش شكل cubic تمام هان
+
+153
+00:12:55,630 --> 00:13:03,590
+إليها free end free end أو apical هان
+
+154
+00:13:03,590 --> 00:13:06,470
+في إليها هذا اسمه lateral
+
+155
+00:13:09,090 --> 00:13:13,070
+باردر وهنا لتحت بيكون basement ايش وظيفة ال
+
+156
+00:13:13,070 --> 00:13:16,830
+basement انها بتفصلها عن ال other underlying
+
+157
+00:13:16,830 --> 00:13:20,510
+connective tissue يعني بتكون شي مفصولة هي اللي
+
+158
+00:13:20,510 --> 00:13:24,650
+مابتكون على شكل membrane هنا و طبعا هنا فيها النوة
+
+159
+00:13:26,050 --> 00:13:29,710
+زي ما واضح بالرسم اللي على ال slides شايفين ال
+
+160
+00:13:29,710 --> 00:13:34,830
+placement اللي هي الطبقة السفلية ال lateral border
+
+161
+00:13:34,830 --> 00:13:38,790
+أو ال lateral surface هذا عبارة عن connective
+
+162
+00:13:38,790 --> 00:13:44,370
+tissue بتلاسق لإنها تالتلي packed tissue فلاي و
+
+163
+00:13:44,370 --> 00:13:48,330
+متلاسقة و متراسة فالتلاسق بيصير و التراس عن طريق
+
+164
+00:13:48,330 --> 00:13:52,610
+ال lateral surface وكمان عندنا ال free apical end
+
+165
+00:13:52,610 --> 00:13:58,480
+أو surfaceمن مميزاتها أيضًا إنها a-vascular يعني
+
+166
+00:13:58,480 --> 00:14:00,900
+الـepithelia اللي في الـcell فيش فيها
+
+167
+00:14:00,900 --> 00:14:08,200
+vascularization على الإطلاق أما فيها إحساس يعني
+
+168
+00:14:08,200 --> 00:14:15,360
+فيها nervous system بيوصلها أما هي also readily
+
+169
+00:14:15,360 --> 00:14:21,770
+dividedtightly packed متراسة متلاسقة جدا مع بعضها
+
+170
+00:14:21,770 --> 00:14:29,790
+فيها أحيانا مواد لاسقة dysmosiums classified
+
+171
+00:14:29,790 --> 00:14:35,950
+according to its shape and number and number of
+
+172
+00:14:35,950 --> 00:14:41,270
+layers إيش يعني لما بنيجي بنقسم ال epithelial cell
+
+173
+00:14:41,270 --> 00:14:46,590
+في عيننا نوعين من التقسيمات the classification
+
+174
+00:14:51,260 --> 00:14:59,280
+according to the number of layers أو
+
+175
+00:14:59,280 --> 00:15:09,180
+according of the shape shape
+
+176
+00:15:09,180 --> 00:15:12,180
+فينا تلت أنواع
+
+177
+00:15:15,030 --> 00:15:18,550
+مهد بنسميها الـ Squamous اللي هي عبارة عن إيش
+
+178
+00:15:18,550 --> 00:15:25,050
+شكلها بهذا الشكل هي ال basement وهيها هيك بيسموها
+
+179
+00:15:25,050 --> 00:15:30,170
+الخرشوفية بتبقى عاملة زي البيضة المقلية بهذا الشكل
+
+180
+00:15:30,170 --> 00:15:32,070
+هذه بنسميها Squamous
+
+181
+00:15:35,030 --> 00:15:41,510
+أما في خلايا تانية في شكلها عامل زي المكعب انا مش
+
+182
+00:15:41,510 --> 00:15:46,630
+كتير شاطرة بالرسم بس خلينا نقول هيك و هيك ويلها
+
+183
+00:15:46,630 --> 00:15:57,870
+قاعدة او هذه كيوبيت كيوبيك او شكلها على شكل column
+
+184
+00:15:57,870 --> 00:16:04,250
+هذا الشكل طويلة وهنا القاعدة كله من ال
+
+185
+00:16:07,820 --> 00:16:13,140
+طبعا هذا على حسب الشيء في أن تلت أنواع هذه هنشوفه
+
+186
+00:16:13,140 --> 00:16:21,620
+في التقسيمة تبعتها ل squamous ل cupoid and
+
+187
+00:16:21,620 --> 00:16:25,540
+incoluminal أما ال layer إذا كانت هي عبارة عن one
+
+188
+00:16:25,540 --> 00:16:34,280
+layer اعتبر أنه هذه cupoid cubic و كمان layerوكمان
+
+189
+00:16:34,280 --> 00:16:39,140
+layer لكن احنا بنسميها على حسب ال layer الأخير
+
+190
+00:16:39,140 --> 00:16:46,020
+فيها قعدنا هنشوف كيف شكل ال layer الأخير الموجود
+
+191
+00:16:46,020 --> 00:16:53,460
+هو احنا بنسميها يا اما اذا كانت مجموعة بنسميها
+
+192
+00:16:53,460 --> 00:17:02,230
+stratified اما اذا كانت one layer بهذا الشكلفهي
+
+193
+00:17:02,230 --> 00:17:09,210
+بتكون simple تمام؟
+
+194
+00:17:09,210 --> 00:17:12,390
+ان شاء الله نكون احنا يعني واضحنا شوية ولو ان
+
+195
+00:17:12,390 --> 00:17:17,530
+الرسم متواضع كتير بس هنشوف عيدنا على ال slide أوضح
+
+196
+00:17:21,000 --> 00:17:24,680
+طبعا covering and lining الابيثيليام ال epidermis
+
+197
+00:17:24,680 --> 00:17:28,160
+of the skin، lining ال blood vessels and duct، ال
+
+198
+00:17:28,160 --> 00:17:31,940
+respiratory و ال reproductive و ال urinary و في
+
+199
+00:17:31,940 --> 00:17:35,860
+منها النوع التاني اللي هي ال glandular اللي عاملة
+
+200
+00:17:35,860 --> 00:17:39,600
+على شكل إجلان وظيفتها تعمل secretion of the gland
+
+201
+00:17:39,600 --> 00:17:43,600
+زي الثيرويد و ال adrenaline و ال secreting إجلان
+
+202
+00:17:44,760 --> 00:17:48,380
+روحنا لل classification اللى تو احنا رسمناه فى
+
+203
+00:17:48,380 --> 00:17:54,020
+الخلف واضحناه ال squamous اللى هى هذه اول واحدة هى
+
+204
+00:17:54,020 --> 00:17:59,180
+عبارة عن خلايا حرشوفية شكلها عاملة بالثبات زى
+
+205
+00:17:59,180 --> 00:18:05,260
+البيضة المقلية صفر فى النص والبيض منتشر على فى
+
+206
+00:18:05,260 --> 00:18:12,920
+المقلة فهى عبارة عن خلاياالكيوبويد عاملة زي كأنها
+
+207
+00:18:12,920 --> 00:18:20,140
+مكعبات مترصة جانب بعضها طبقة واحدة فهي كيوبويد أما
+
+208
+00:18:20,140 --> 00:18:25,680
+الكولومينار فهي عبارة عن إيش؟أعمدة في القاعدة
+
+209
+00:18:25,680 --> 00:18:30,260
+تبعتها أو قريب من القاعدة موجودة انموها زي ما احنا
+
+210
+00:18:30,260 --> 00:18:35,040
+شايفينها هنا أما بالنسبة لل arrangement ال
+
+211
+00:18:35,040 --> 00:18:38,520
+classification التاني عدد الطبقات أو number of
+
+212
+00:18:38,520 --> 00:18:42,360
+layers في عندنا ال simple وفي عندنا ال stratified
+
+213
+00:18:42,360 --> 00:18:46,120
+وفي عندنا ال pseudo stratified طبعا هنا الصورة
+
+214
+00:18:46,120 --> 00:18:50,840
+المضحكة عندنا ال simple انها one layerعبارة عن one
+
+215
+00:18:50,840 --> 00:18:55,900
+layer أما الـ stratified فهي عندنا مجموعة من ال
+
+216
+00:18:55,900 --> 00:19:01,000
+layers من ال cells المختلفة لكن احنا عادة عندنا
+
+217
+00:19:01,000 --> 00:19:04,880
+هنشوف بنسميها بنسميها حسب الطبقة الأخيرة من ال
+
+218
+00:19:04,880 --> 00:19:10,540
+cells أما ال pseudo stratified فهي عبارةبالشكل أو
+
+219
+00:19:10,540 --> 00:19:14,800
+المنظر تبعها مثلا هي خلينا نقول ال basement هيو
+
+220
+00:19:14,800 --> 00:19:22,620
+تمام؟ في عندنا هنا مثلا سل و سل صغيرة و بعدين جاي
+
+221
+00:19:22,620 --> 00:19:26,920
+سل كبيرة هنا و بعدين سل صغيرة و بعدين سل كبيرة هنا
+
+222
+00:19:26,920 --> 00:19:30,520
+و يكونوا متلاسقة هادي مع هادي كمان بهذا الشكل
+
+223
+00:19:30,520 --> 00:19:37,660
+تمام؟ و هنا في سل و هنا في عنديالنواء وهنا النواء
+
+224
+00:19:37,660 --> 00:19:44,080
+تمام؟ طيب هذا الشكل اللي احنا شايفينه صغير وكبير
+
+225
+00:19:44,080 --> 00:19:50,660
+بيبينلي كأنها هي طبقات لكن هي في الحقيقة مش طبقات
+
+226
+00:19:50,660 --> 00:19:56,580
+هي عبارة عن طبقة خليني بس أورجيكم إياها على ال
+
+227
+00:19:56,580 --> 00:20:01,000
+slide تقريبا احنا في ال slide هذه موجودة
+
+228
+00:20:05,800 --> 00:20:09,440
+هنوصلها عندنا بلاش احنا نضيع كتير وقت فيها هي
+
+229
+00:20:09,440 --> 00:20:15,140
+عبارة قلنا عن إيش؟ عن شكلها و كأنها طبقية لكن هي
+
+230
+00:20:15,140 --> 00:20:21,180
+بالحقيقة مش طبقات هي عبارة عن one line لكن فيها سل
+
+231
+00:20:21,180 --> 00:20:23,540
+كبيرة وسل صغيرة
+
+232
+00:20:31,060 --> 00:20:35,520
+يبقى هنا سيمبل مستراتفايف و سودو كلمة سودو يعني
+
+233
+00:20:35,520 --> 00:20:42,060
+كاذب او بالعربي بتطلع false يعني سودو false
+
+234
+00:20:42,060 --> 00:20:51,500
+السيمبل ابثيلام تيشيو هي عبارة عن أربع أنواع سيمبل
+
+235
+00:20:51,500 --> 00:20:58,060
+squamous شكلها هرشوفي وطبقة line واحد سيمبل كيقاعد
+
+236
+00:20:58,860 --> 00:21:02,980
+and simple columnar وفي عندنا الـ pseudostratified
+
+237
+00:21:02,980 --> 00:21:06,060
+وكأن هو بيقول إنها stratified و مش stratified
+
+238
+00:21:06,060 --> 00:21:11,960
+فالحقيقة هي عبارة عن one line أو طبقة واحدة فيها
+
+239
+00:21:11,960 --> 00:21:17,720
+cells طويلة و cells قصيرة متراصة فبتيجي فبتبدأ
+
+240
+00:21:17,720 --> 00:21:21,820
+المكان ال wall موجودة فيها عشان هيك تطلع شكلها و
+
+241
+00:21:21,820 --> 00:21:26,840
+كإنها stratified طبقية أو طبقات ال epithelial
+
+242
+00:21:26,840 --> 00:21:31,230
+tissueالـ single squamous epithelial زي ما احنا
+
+243
+00:21:31,230 --> 00:21:35,230
+شايفينها بهذا الشكل هي في عندنا ال basement على
+
+244
+00:21:35,230 --> 00:21:38,350
+طول ال basement فصل ال epithelial cell عن ال
+
+245
+00:21:38,350 --> 00:21:42,110
+connective tissue و في نفس الوقت أعطانا الشكل اللي
+
+246
+00:21:42,110 --> 00:21:48,150
+احنا وصفناه قبل شوية عبارة عن طبقة واحدة من ال
+
+247
+00:21:48,150 --> 00:21:49,730
+cells
+
+248
+00:21:57,670 --> 00:22:04,030
+أما ال symbol squamous فهي موجودة وين؟ موجودة في
+
+249
+00:22:04,030 --> 00:22:07,890
+lining ال blood vessels و ال lymphatic vessels و
+
+250
+00:22:07,890 --> 00:22:15,610
+ال air sacs اللي هي ال alveoli single
+
+251
+00:22:15,610 --> 00:22:21,710
+layer of flat cells فهذه ال symbol squamous cell
+
+252
+00:22:21,710 --> 00:22:24,850
+زي ما احنا شايفينها بالصورة
+
+253
+00:22:26,300 --> 00:22:30,440
+هي أشكال مختلفة موجودة في أماكن مضبوعة .. الموضوع
+
+254
+00:22:30,440 --> 00:22:35,100
+ال .. بين موجودة simple squamous فما إحنا شايفينها
+
+255
+00:22:35,100 --> 00:22:41,420
+بالرسم الموضع حوالين
+
+256
+00:22:41,420 --> 00:22:45,100
+البريتانيا أو ال abdominal cavity
+
+257
+00:22:48,360 --> 00:22:53,940
+أما الـ simple cuboid أو cuboidal cell فهذا شكلها
+
+258
+00:22:53,940 --> 00:22:57,100
+عبارة عن طبقة متراسة هي عندنا ال connective tissue
+
+259
+00:22:57,100 --> 00:23:01,820
+و عندنا ال basement هنا شكل المكعب للخلية و هنا
+
+260
+00:23:01,820 --> 00:23:03,620
+النوع
+
+261
+00:23:06,580 --> 00:23:10,700
+طبعا إيش وظيفتها؟ مانوجودة .. موجودة في ال kidney
+
+262
+00:23:10,700 --> 00:23:16,500
+tubes، ال ovaries، some of the gland هي عبارة عن
+
+263
+00:23:16,500 --> 00:23:21,860
+simple أو one layer of cube shared cells
+
+264
+00:23:24,860 --> 00:23:30,180
+و هدا إحدى الأشكال هي حاططنا في ال pancreas كيف
+
+265
+00:23:30,180 --> 00:23:36,560
+شكلها و كيف بتكون تركبتها و هي عبارة عن one layer
+
+266
+00:23:36,560 --> 00:23:42,620
+of occupied cells أما
+
+267
+00:23:42,620 --> 00:23:47,440
+ال columnar فهي زي ما هي موضحة بالشكل زي ما إحنا
+
+268
+00:23:47,440 --> 00:23:56,110
+شايفين في عندنا هي basement وهي في عندناالـ C وفي
+
+269
+00:23:56,110 --> 00:24:00,470
+الغالب بيكون فيه سيليا أو أهداب موجودة أو زغب ما
+
+270
+00:24:00,470 --> 00:24:03,910
+نسميه احنا الزغب يبقى بقى a single layer of
+
+271
+00:24:03,910 --> 00:24:08,290
+elongated cells للـ nuclei usually near the
+
+272
+00:24:08,290 --> 00:24:12,950
+basement عادة بتكون قريبة من ال basementof the
+
+273
+00:24:12,950 --> 00:24:17,770
+membrane sometimes بتكون في عندها في نهاياتها حاجة
+
+274
+00:24:17,770 --> 00:24:21,710
+اسمها السيليا ما بنسميها احنا الأهداب وكمان ممكن
+
+275
+00:24:21,710 --> 00:24:24,890
+يكون حاجة اسمها ال microvilli الزغب اللي احنا
+
+276
+00:24:24,890 --> 00:24:29,010
+بنتكلم عنه بنقول عنه الزغب ان هي شعيرات صغيرة كتير
+
+277
+00:24:29,370 --> 00:24:33,670
+often have goblets cells زي عاملة بعض ال cells
+
+278
+00:24:33,670 --> 00:24:38,250
+اللي عاملة زي جيوب أو زي الكؤوس خلينا نسميها
+
+279
+00:24:38,250 --> 00:24:43,110
+موجودة في ال ureterus و ال stomach و ال intestine
+
+280
+00:24:43,110 --> 00:24:50,710
+و هذا شكلها كيف بتكون موجودة بالخلية و اذا احنا
+
+281
+00:24:50,710 --> 00:24:57,250
+بتطلعنا على ال goblets اللي موجودة بهذا المكان
+
+282
+00:25:02,550 --> 00:25:07,610
+السنب الكولومير و ال سيليا هى احنا شايفينها زى
+
+283
+00:25:07,610 --> 00:25:17,450
+موجودة فى القناة تلوب او فى الورينالى tubes او فى
+
+284
+00:25:17,450 --> 00:25:22,670
+الوتراين tubes هذا
+
+285
+00:25:22,670 --> 00:25:27,510
+الى علاقة بموضوع التطبيق وخروج البويضة واستقطاب
+
+286
+00:25:27,510 --> 00:25:32,030
+الحيوان ما نقولها كده عشان هي كتفيها السيليا
+
+287
+00:25:36,230 --> 00:25:42,510
+أما الـ Sodostratified Ciliated Epithelium هي
+
+288
+00:25:42,510 --> 00:25:47,250
+عبارة عن single layer of elongated سل طويلة زي ما
+
+289
+00:25:47,250 --> 00:25:52,410
+احنا وضحناها بالرسم وكمان موجود فيها نواة بس مش
+
+290
+00:25:52,410 --> 00:25:58,920
+على نفس المستوىممكن تكون الـwa في ال base and
+
+291
+00:25:58,920 --> 00:26:05,900
+above أبير استرياتي تطلع فيها فكرها استرياتي دائما
+
+292
+00:26:05,900 --> 00:26:09,360
+أو غالبا تكون فيها السيليا اللي هي الأهداب وال
+
+293
+00:26:09,360 --> 00:26:13,650
+goblet cellsتاقما بتكون موجودة في ال respiratory
+
+294
+00:26:13,650 --> 00:26:17,510
+pathway احنا بنفهم ان وجود السيلي عشان تساعد على
+
+295
+00:26:17,510 --> 00:26:21,970
+عملية ال expectoration اللى ممكن تساعد على خروج ال
+
+296
+00:26:21,970 --> 00:26:25,950
+mucus او ال excessive mucus او ال unwanted mucus
+
+297
+00:26:25,950 --> 00:26:29,030
+اللى موجود في ال respiratory tract
+
+298
+00:26:32,980 --> 00:26:37,100
+وهذا القراصان التاني بيوضح موجود الـ Sodium
+
+299
+00:26:37,100 --> 00:26:41,800
+stratified epithelia موجود في التراكيا لأنه دايما
+
+300
+00:26:41,800 --> 00:26:44,200
+بيحتوي على الأهداف اللي ساعد على عملية الـ
+
+301
+00:26:44,200 --> 00:26:49,560
+expectorationأما الـ Stratified اللي احنا بنسميها
+
+302
+00:26:49,560 --> 00:26:53,840
+الطبقية أو المجموعة يعني according ال
+
+303
+00:26:53,840 --> 00:26:56,300
+classification according to the number of number
+
+304
+00:26:56,300 --> 00:27:01,320
+of layers فعنا ال Stratified squamous و Stratified
+
+305
+00:27:01,320 --> 00:27:06,960
+cuboid وعنا ال Stratified columnar يعني نفس مواعي
+
+306
+00:27:06,960 --> 00:27:13,800
+الخلايا لكن مكونة من عدة طبقات وهذا
+
+307
+00:27:16,080 --> 00:27:20,860
+مظهر أو خلّينا نقول رسم توضيحي Gestratified
+
+308
+00:27:20,860 --> 00:27:25,520
+Squamous اللي هي الحرشوفية لكن الطبقية many cells
+
+309
+00:27:25,520 --> 00:27:29,300
+of layer top cell are flat لإن احنا عادة لما
+
+310
+00:27:29,300 --> 00:27:32,440
+بنسميها بنسمي في الطبقة الأخيرة مانظرش للطبقات
+
+311
+00:27:32,440 --> 00:27:36,680
+التانية في الطبقة الأخيرة الشكلة فبنسمي السلب هذا
+
+312
+00:27:36,680 --> 00:27:41,980
+الشكل top cell are flat can accumulate keratin إيش
+
+313
+00:27:41,980 --> 00:27:46,550
+يعني keratin؟ فيه protein في الجسم اسمه keratinهذا
+
+314
+00:27:46,550 --> 00:27:53,030
+في خلايا لكن ميتة أو خلايا مافيش فيها نوعهذه
+
+315
+00:27:53,030 --> 00:27:59,230
+بتتكون ال outer layer of the skin وكمان ال oral
+
+316
+00:27:59,230 --> 00:28:03,470
+cavity و ال vagina و ال anal canal طبعا هذه
+
+317
+00:28:03,470 --> 00:28:07,230
+وظيفتها الخلايا اللي فيها الكيروتينية بتساعد على
+
+318
+00:28:07,230 --> 00:28:11,690
+shock absorption بتساعد على ال .. هذه بيسميها احنا
+
+319
+00:28:11,690 --> 00:28:16,670
+خلايا ميتة بتخفف الصدمات على ال skin أو على
+
+320
+00:28:16,670 --> 00:28:18,130
+الأماكن هذه
+
+321
+00:28:22,970 --> 00:28:27,070
+هذا شكل من الـ stratified squamous موجود في ال
+
+322
+00:28:27,070 --> 00:28:33,490
+vagina اما
+
+323
+00:28:33,490 --> 00:28:38,070
+الكيوبويت two to three layers of cube-shaped cells
+
+324
+00:28:38,070 --> 00:28:41,330
+line the ducts of mammary gland، الممر اللي هي
+
+325
+00:28:41,330 --> 00:28:46,010
+خلايا الثدية، sweating gland، salivary gland اللي
+
+326
+00:28:46,010 --> 00:28:50,180
+هي بتفرز اللعاب و كذلك ال pancreasزي ما احنا
+
+327
+00:28:50,180 --> 00:28:55,340
+شايفينها بالصورة مجموعة من الـ cubic أو الـ
+
+328
+00:28:55,340 --> 00:29:00,400
+cuboidal cells لكن أكتر من طبقة و طبعا هذا عادة
+
+329
+00:29:00,400 --> 00:29:04,280
+الرسم بعيد و بيزيد بإن في عندنا ال basement اللي
+
+330
+00:29:04,280 --> 00:29:07,940
+بيفصل ال connective tissue عن ال cells و في شايفين
+
+331
+00:29:07,940 --> 00:29:11,960
+ال end هنا ال abical surfaceهنا و في كمان في ال
+
+332
+00:29:11,960 --> 00:29:15,360
+borders هذه او ال lateral borders اللي بيكون
+
+333
+00:29:15,360 --> 00:29:20,340
+بيحتوي على المواد اللاسقة اللي بتخليها tightly
+
+334
+00:29:20,340 --> 00:29:27,000
+closed او packed tissue في
+
+335
+00:29:27,000 --> 00:29:31,860
+عندنا ال stratified Q-Border الابيتيليام اللي
+
+336
+00:29:31,860 --> 00:29:38,430
+موجودة في ال Oesophagus وهذا شكلهاأما ال columnar
+
+337
+00:29:38,430 --> 00:29:43,490
+فهي عبارة عن stratified columnar بنفس الطريقة اللي
+
+338
+00:29:43,490 --> 00:29:47,010
+احنا بنتكلم عنها ان هي عبارة عن مجموعة من الطبقات
+
+339
+00:29:47,010 --> 00:29:49,650
+احنا بنطلع على الطبقة الأخيرة زي ما احنا شايفين
+
+340
+00:29:49,650 --> 00:29:54,790
+كيف شكل الطبقة الأخيرة فهي شكلها طولي أو عمودية
+
+341
+00:29:54,790 --> 00:29:58,710
+فبنسميها stratified columnar
+
+342
+00:30:01,090 --> 00:30:05,410
+بتكون الطبقة الخارجية مخدة شكل ال column اما
+
+343
+00:30:05,410 --> 00:30:09,570
+الطبقات التانية مخدة شكل look the pipe line part
+
+344
+00:30:09,570 --> 00:30:17,870
+of male urethra and part of pharynx وهذا رسم
+
+345
+00:30:17,870 --> 00:30:23,630
+توضيحي في حاجة اسمها transitional طب ال
+
+346
+00:30:23,630 --> 00:30:31,200
+transitional هذهليش اتسمت هيك؟ Transitional انها
+
+347
+00:30:31,200 --> 00:30:38,540
+many cell layers, cubic shape and elongated cell
+
+348
+00:30:38,540 --> 00:30:43,440
+هذه ليش اتسمت هيك؟ اتكلم عن احنا مثلا عن البلدر
+
+349
+00:30:43,440 --> 00:30:47,080
+البلدر بتحتوي على ال urine البلدر لما بيكون فش
+
+350
+00:30:47,080 --> 00:30:51,380
+فيها urine بتكون صغيرة طبعا فبيكون شكل ال cell
+
+351
+00:30:51,380 --> 00:30:55,560
+فيها columnar بهذا الشكل
+
+352
+00:31:15,400 --> 00:31:21,340
+تمام؟ تمام؟ تمام؟
+
+353
+00:31:21,340 --> 00:31:24,780
+تمام؟ تمام؟ تمام؟
+
+354
+00:31:41,530 --> 00:31:48,050
+تخيلوا شغالة لما بتنشد بتنشد زي ال blooder ال
+
+355
+00:31:48,050 --> 00:31:51,270
+blooder لما تكون full of urine بتنشد فبصير شكل
+
+356
+00:31:51,270 --> 00:31:56,230
+الخلايا فيها كده cubic تمام لما بيروح الضغط بصير
+
+357
+00:31:56,230 --> 00:32:04,210
+شكلها عمودي فهي بتحتوي على هذا النوع من ال cells
+
+358
+00:32:04,210 --> 00:32:08,330
+lining ال blooder و ال urethra and urethra
+
+359
+00:32:22,500 --> 00:32:28,440
+أما الـ glandular Epithelium composed of cell that
+
+360
+00:32:28,440 --> 00:32:33,320
+specialized to produce and secretes substance يبقى
+
+361
+00:32:33,320 --> 00:32:39,040
+احنا في عندنا secretion وكمان بيبقى production ل
+
+362
+00:32:39,040 --> 00:32:46,260
+ال hormones زي ال endocrine، glans وفي عندنا ال
+
+363
+00:32:46,260 --> 00:32:52,080
+exocrine، glans ال endocrine مافيش فيها ducts
+
+364
+00:32:54,470 --> 00:32:58,650
+and secret their product directly into the
+
+365
+00:32:58,650 --> 00:33:02,250
+interstitial fluid and blood stream لأن هي عبارة
+
+366
+00:33:02,250 --> 00:33:06,850
+عن hormone داخلية endocrine داخلية اتكلم عن ال
+
+367
+00:33:06,850 --> 00:33:11,090
+exocrine اللي هي الخارجية هذه ليش lack of duct
+
+368
+00:33:11,090 --> 00:33:14,490
+مافيش فيها قنوات لأن هي بتفرز في blood stream
+
+369
+00:33:14,490 --> 00:33:19,030
+مباشرة و تفرز في ال interstitial fluid مباشرة فهي
+
+370
+00:33:19,030 --> 00:33:25,440
+مافيش فيها ducts سماءطيب ال hormones عبارة عن أيه؟
+
+371
+00:33:25,440 --> 00:33:28,860
+هي عبارة عن مواد كيميائية بيفرزها .. بيفرزها ..
+
+372
+00:33:28,860 --> 00:33:33,560
+بتفرزها هذه ال gland حتى تنظم الجسم، تعمل حالة من
+
+373
+00:33:33,560 --> 00:33:38,120
+ال hemostasis، تضام الجسم أو توازن الجسم، التوازن
+
+374
+00:33:38,120 --> 00:33:41,880
+الداخلي والتوازن الخارجي، هذا ال .. ال .. ال .. ال
+
+375
+00:33:41,880 --> 00:33:45,550
+Indo وال Exocrine system بالضبطخلّينا نقول أو الـ
+
+376
+00:33:45,550 --> 00:33:48,970
+endocrine system هو اللي بيتحكم فيه فالـ hormones
+
+377
+00:33:48,970 --> 00:33:52,950
+عبارة عن إيه؟ chemical messengers to influence
+
+378
+00:33:52,950 --> 00:33:56,930
+cell activity elsewhere in the body يعني ممكن هي
+
+379
+00:33:56,930 --> 00:34:01,910
+بتفرز من مكان لكن بتكون تأثيرها في أماكن تانية على
+
+380
+00:34:01,910 --> 00:34:05,270
+الجسم عشان هي بتفرز في blood steam نفسه في الـ
+
+381
+00:34:05,270 --> 00:34:09,330
+interstitial effluent أما الـ exocrine هي أخر
+
+382
+00:34:11,570 --> 00:34:14,510
+محاضرتنا لليوم مش هنكون مطولانش عليكوا الـ
+
+383
+00:34:14,510 --> 00:34:17,890
+Exocrine اللي هو الإفراز الخارجي Maintain their
+
+384
+00:34:17,890 --> 00:34:21,430
+contact with the epithelial surface by means of
+
+385
+00:34:21,430 --> 00:34:24,730
+duct يعني ال Exocrine فيها duct أما ال Endocrine
+
+386
+00:34:24,730 --> 00:34:27,670
+مافيش فيها duct لأنها بتفرز في بلد steam نفسها
+
+387
+00:34:27,670 --> 00:34:35,130
+وهذه بتروح عن طريق قنوات عشان تطلعها للخارجsecrets
+
+388
+00:34:35,130 --> 00:34:38,870
+materials onto the surface of the skin or onto the
+
+389
+00:34:38,870 --> 00:34:44,710
+epithelial surface lining and internal passageway
+
+390
+00:34:45,920 --> 00:34:49,080
+ننهي محاضرتنا لليوم عشان الأسبوع اللي جاي ان شاء
+
+391
+00:34:49,080 --> 00:34:52,420
+الله يكون أو يوم الأتنين أسبوع هذا ان شاء الله
+
+392
+00:34:52,420 --> 00:34:56,320
+يكون محاضرة عن باقى ال classifications تبع ال
+
+393
+00:34:56,320 --> 00:34:59,760
+tissue ال connective tissue و ال muscle tissue و
+
+394
+00:34:59,760 --> 00:35:04,240
+ال nerve tissue و يعطيكم على القافية السلام عليكم
+
+395
+00:35:04,240 --> 00:35:05,060
+و رحمة الله
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..ab171fd3c96a68c3d65d8db2e9481e59284a683c
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s_raw.json
@@ -0,0 +1 @@
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146901, "start": 1452.31, "end": 1469.01, "text": "of the membrane sometimes بتكون في عندها في نهاياتها حاجة اسمها السيليا ما بنسميها احنا الأهداب وكمان ممكن يكون حاجة اسمها ال microvilli الزغب اللي احنا بنتكلم عنه بنقول عنه الزغب ان هي شعيرات صغيرة كتير", "tokens": [2670, 264, 19651, 2171, 39894, 30544, 8978, 43242, 11296, 8978, 8717, 11296, 1829, 9307, 11296, 11331, 26108, 3660, 24525, 2304, 11296, 21136, 26895, 25528, 19446, 44945, 38251, 1829, 11296, 1975, 5016, 8315, 16247, 3224, 3215, 16758, 4032, 24793, 7649, 3714, 43020, 7251, 30544, 11331, 26108, 3660, 24525, 2304, 11296, 2423, 4532, 85, 31922, 6024, 110, 17082, 3555, 13672, 1829, 1975, 5016, 8315, 44945, 2655, 4117, 19528, 18871, 3224, 44945, 39648, 18871, 3224, 6024, 110, 17082, 3555, 16472, 39896, 13412, 3615, 13546, 9307, 20328, 17082, 48923, 9122, 2655, 13546], "avg_logprob": -0.1845154521170627, "compression_ratio": 1.7295918367346939, "no_speech_prob": 3.4570693969726562e-06, "words": [{"start": 1452.31, "end": 1452.61, 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63, "seek": 153203, "start": 1502.55, "end": 1532.03, "text": "السنب الكولومير و ال سيليا هى احنا شايفينها زى موجودة فى القناة تلوب او فى الورينالى tubes او فى الوتراين tubes هذا الى علاقة بموضوع التطبيق وخروج البويضة واستقطاب الحيوان ما نقولها كده عشان هي كتفيها السيليا", "tokens": [6027, 3794, 1863, 3555, 33251, 12610, 20498, 13546, 4032, 2423, 8608, 26895, 25528, 8032, 7578, 1975, 5016, 8315, 13412, 995, 33911, 9957, 11296, 30767, 7578, 3714, 29245, 23328, 3660, 6156, 7578, 25062, 8315, 3660, 6055, 1211, 2407, 3555, 1975, 2407, 6156, 7578, 2423, 13063, 9957, 6027, 7578, 21458, 1975, 2407, 6156, 7578, 2423, 35473, 23557, 9957, 21458, 23758, 2423, 7578, 11203, 995, 28671, 4724, 2304, 2407, 11242, 45367, 16712, 9566, 21292, 4587, 4032, 34740, 29245, 29739, 45865, 11242, 3660, 36764, 14851, 47432, 16758, 21542, 1829, 2407, 7649, 19446, 8717, 39648, 11296, 9122, 3215, 3224, 6225, 8592, 7649, 39896, 9122, 2655, 41185, 11296, 21136, 26895, 25528], "avg_logprob": -0.4030070791266999, 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2100.42, "word": " nerve", "probability": 0.91357421875}, {"start": 2100.42, "end": 2101.78, "word": " tissue", "probability": 0.97998046875}, {"start": 2101.78, "end": 2101.98, "word": " و", "probability": 0.78857421875}, {"start": 2101.98, "end": 2102.54, "word": " يعطيكم", "probability": 0.8582763671875}, {"start": 2102.54, "end": 2102.78, "word": " على", "probability": 0.44970703125}, {"start": 2102.78, "end": 2103.24, "word": " القافية", "probability": 0.6585286458333334}, {"start": 2103.24, "end": 2103.64, "word": " السلام", "probability": 0.7822265625}, {"start": 2103.64, "end": 2104.24, "word": " عليكم", "probability": 0.95849609375}, {"start": 2104.24, "end": 2104.44, "word": " و", "probability": 0.99560546875}, {"start": 2104.44, "end": 2104.78, "word": " رحمة", "probability": 0.8499348958333334}, {"start": 2104.78, "end": 2105.06, "word": " الله", "probability": 0.97314453125}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2105.98025, "duration_after_vad": 1952.9443749999953}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..83495a1cab8b7685e86782b53db0c73ce5749568
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/hvJ7Nkm_U4s_raw.srt
@@ -0,0 +1,1580 @@
+1
+00:00:05,110 --> 00:00:09,450
+بسم الله الرحمن الرحيم حضرتنا التالتة في مساق ال
+
+2
+00:00:09,450 --> 00:00:12,770
+anatomy هنتكلم فيها عن ال tissue level
+
+3
+00:00:12,770 --> 00:00:18,990
+organization موضوعنا اليوم أنواع ال tissue طبعا زي
+
+4
+00:00:18,990 --> 00:00:23,250
+ما احنا عارفين ان مجموعة ال cells قولنا المكون
+
+5
+00:00:23,250 --> 00:00:28,750
+الأساسي هي ال cell مجموعة من ال cells بتعملنا
+
+6
+00:00:28,750 --> 00:00:33,250
+tissue مجموعة من ال tissue بتعمل organ
+
+7
+00:00:37,360 --> 00:00:43,060
+تمام؟ ومجموعة من ال organs بتعملنا
+
+8
+00:00:43,060 --> 00:00:47,600
+ال system و بعدين ال system بيعمل ال body فاحنا من
+
+9
+00:00:47,600 --> 00:00:54,600
+هان لهان اليوم هنتكلم أنواع ال type of tissue
+
+10
+00:00:56,780 --> 00:01:00,680
+طبعا في عندنا four main types of tissue طبعا قولنا
+
+11
+00:01:00,680 --> 00:01:04,140
+مجموعة من ال cells المتشابهه بتكون ليه؟ ال tissue
+
+12
+00:01:04,140 --> 00:01:09,260
+بتكون from common embryologic origin and have the
+
+13
+00:01:09,260 --> 00:01:14,900
+same function طبعا هذا العلم اللي بيدرس ال tissue
+
+14
+00:01:14,900 --> 00:01:19,280
+هو علم بنسميه احنا علم الhistology طبعا عندنا four
+
+15
+00:01:19,280 --> 00:01:25,400
+types of tissue عندنا ال epithelial
+
+16
+00:01:30,740 --> 00:01:37,160
+وعنا ال connective tissue وعنا
+
+17
+00:01:37,160 --> 00:01:44,690
+ال muscle tissue وعنا ال nerve tissueطبعا أربعة
+
+18
+00:01:44,690 --> 00:01:50,890
+type من ال tissue هو مكون لأو خلينا نقول أنواع ال
+
+19
+00:01:50,890 --> 00:01:54,270
+tissue اللي موجودة في الجسم اليوم تركزنا في
+
+20
+00:01:54,270 --> 00:01:59,150
+محاضرتنا على ال epithelial tissue و أنواعها و
+
+21
+00:01:59,150 --> 00:02:03,650
+تركبتها و كيف احنا ممكن نتعرف على الوظيفة اللي هي
+
+22
+00:02:03,650 --> 00:02:04,830
+بتقدمها
+
+23
+00:02:06,860 --> 00:02:11,480
+الـ Epithelial tissue طبيعتها هي مسموها الخلايا
+
+24
+00:02:11,480 --> 00:02:16,840
+الطلاقية موجودة تقريبا في كل أعضاء الجسم اللي هو
+
+25
+00:02:16,840 --> 00:02:22,560
+ضائف متعددة موجودة على ال surface of the skinكمان
+
+26
+00:02:22,560 --> 00:02:26,680
+موجودة على كل الأماكن التجاوف إذا بنتذكر في محاضرة
+
+27
+00:02:26,680 --> 00:02:30,660
+ال Anatomy الأولى قلنا فيه أن التجاوف الموجودة أو
+
+28
+00:02:30,660 --> 00:02:33,880
+ال cavities اللي موجودة فهي مبطنة لكل ال cavities
+
+29
+00:02:33,880 --> 00:02:38,120
+الموجودة في الجسم اللي هي ال pleural cavity، ال
+
+30
+00:02:38,120 --> 00:02:42,260
+cardiac، ال peritoneum، ال abdominal cavitiesكمان
+
+31
+00:02:42,260 --> 00:02:45,540
+موجودة في الـ ducts في كل القنوات اللي موجودة في
+
+32
+00:02:45,540 --> 00:02:50,540
+الجسم و بتكون مع بعض ال glands يبقى هي ال
+
+33
+00:02:50,540 --> 00:02:54,780
+epithelial cells هنتعرف على وظيفتها لما نبدأ فيها
+
+34
+00:02:54,780 --> 00:02:57,080
+لكن نروح على ال connective tissue ال connective
+
+35
+00:02:57,080 --> 00:03:00,240
+tissue الخلايا الضامة بيسموها الخلايا اللي بتربط
+
+36
+00:03:00,240 --> 00:03:06,860
+الأشياء مع بعضها في الجسم طبعا بتساعد و بتدعم ال
+
+37
+00:03:06,860 --> 00:03:11,830
+structure سبعة الجسمall together and store energy
+
+38
+00:03:11,830 --> 00:03:18,050
+and كمان provide immune system طبعا ال muscle
+
+39
+00:03:18,050 --> 00:03:22,190
+tissue ال muscle tissue هي عبارة عن الخلية المكونة
+
+40
+00:03:22,190 --> 00:03:27,090
+للعضلات العضلات بما فيها ال muscle نفسها و ال
+
+41
+00:03:27,090 --> 00:03:30,260
+tendon و كل ال connective tissuesاللي حواليها لكن
+
+42
+00:03:30,260 --> 00:03:34,140
+احنا نتكلم عن العضلة العضلة هي نسيج خاص اما ال
+
+43
+00:03:34,140 --> 00:03:40,200
+nerve tissue فهي العضلة المكونة لجهاز ال sorry ال
+
+44
+00:03:40,200 --> 00:03:45,500
+tissue المكونة لجهاز ال nervous system طبيعتها
+
+45
+00:03:47,010 --> 00:03:53,170
+بتقدم عندنا ال electricity نعرفين أن الجسم عبارة
+
+46
+00:03:53,170 --> 00:03:57,590
+عن مواصلات بتوصل ال orderات من الدماغ ال spinal
+
+47
+00:03:57,590 --> 00:04:03,290
+cord ل الأطراف لجميع أجزاء الجسم فهي بتعملنا ال
+
+48
+00:04:03,290 --> 00:04:06,830
+electrical signal detected change طبعا احنا لو
+
+49
+00:04:06,830 --> 00:04:10,910
+احنا طلعنا في جو بارد أو دخلنا على جو سخن كيف
+
+50
+00:04:10,910 --> 00:04:14,350
+جسمنا بتلقى هذه الإشارة بتلقها عن طريق ال nerve
+
+51
+00:04:14,350 --> 00:04:18,240
+tissueو ال nerve cell نفسها كمان respond to
+
+52
+00:04:18,240 --> 00:04:22,480
+nervous impulses أي impulse بتيجي زواء عن طريق ال
+
+53
+00:04:22,480 --> 00:04:25,340
+reflex مدينا ايدنا مسكنا حاجة ساخنة على طول احنا
+
+54
+00:04:25,340 --> 00:04:29,100
+بنرميها دعزنا على مسمارة على طول بنبعد عنه أي
+
+55
+00:04:29,100 --> 00:04:32,960
+مشكلة ممكن تواجهنا مع ال external environment أو
+
+56
+00:04:32,960 --> 00:04:36,660
+ال internal environment بتكون الاستجابة الأولى لل
+
+57
+00:04:36,660 --> 00:04:42,050
+nerve tissueطبعا احنا كيف بنتعرف على خصائص أو
+
+58
+00:04:42,050 --> 00:04:45,690
+بنتشخص الأمراض اللي بتصيب ال tissue عن طريق حاجة
+
+59
+00:04:45,690 --> 00:04:50,070
+اسمها biopsy ال biopsy هي عبارة عن removal of
+
+60
+00:04:50,070 --> 00:04:54,270
+tissue عشان احنا نعملها بيئة معينة و نشوفها under
+
+61
+00:04:54,270 --> 00:04:58,590
+microscope و ندرس خصائصها و المشكلات اللي ممكن
+
+62
+00:04:58,590 --> 00:05:03,630
+تكون أصبحت موجودة فيهاأساس احنا لما بنشخص ال
+
+63
+00:05:03,630 --> 00:05:06,690
+cancer بناخد ال biopsy هذه او بناخد الخزعة ما
+
+64
+00:05:06,690 --> 00:05:11,190
+نسميه بالخزعة و بنحاول بنعملها بنوديها على ال
+
+65
+00:05:11,190 --> 00:05:15,250
+pathology و هم بيعملوها اللازم و بتعرفوا هل فيها
+
+66
+00:05:15,250 --> 00:05:19,050
+خلايا سرطانية او لأ مثلا في حالات ال myopathy
+
+67
+00:05:19,050 --> 00:05:22,190
+بيشوفوا اذا في فعلا existing myopathy ولا لأ بناخد
+
+68
+00:05:22,190 --> 00:05:25,610
+خزعة من العضلات و بنروح بنوديها على المختبرات
+
+69
+00:05:25,610 --> 00:05:30,660
+المتقدمة و بيقولوا ان هذا والله الطفل عندهما يبثي
+
+70
+00:05:30,660 --> 00:05:38,440
+أو ما عندهوش ما يبثي طبعا فيه لها الفزعة العادية
+
+71
+00:05:38,440 --> 00:05:41,860
+أو فيه ممكن أننا ناخد ال alternative method ناخد
+
+72
+00:05:41,860 --> 00:05:46,200
+ال needle نعمل aspiration نحط زي ما احنا بنشوف في
+
+73
+00:05:46,200 --> 00:05:53,350
+الصورة الموجودة أمامنا ممكن أننا ندخل قبرة هنانيدل
+
+74
+00:05:53,350 --> 00:05:58,570
+و نسحب من السائل و نقدمه للفحص أو ندخل لداخل
+
+75
+00:05:58,570 --> 00:06:04,950
+القناة بنسموها ال core بنروح بناخد النواة و بناخد
+
+76
+00:06:04,950 --> 00:06:08,290
+خزعة كبيرة أكبر شوية من الخزعة اللي بناخدها عن
+
+77
+00:06:08,290 --> 00:06:13,920
+طريق ال needle أو أنه بنفتح فتحة هيك و بتنشلكل الـ
+
+78
+00:06:13,920 --> 00:06:17,560
+gland أو ال tissue اللى احنا بدنا اللى صار فيها
+
+79
+00:06:17,560 --> 00:06:24,060
+تغيرات و بناخدها و بنعملها بفحص عند ال pathology
+
+80
+00:06:24,060 --> 00:06:28,660
+طب إيش ال function لل Epithelia ال tissue طبعا
+
+81
+00:06:28,660 --> 00:06:36,420
+بتشتغل أكتر من من function بتشتغل على لو أخدنا
+
+82
+00:06:36,420 --> 00:06:39,380
+اليوم موضوعنا عن ال Epithelia
+
+83
+00:06:45,720 --> 00:06:50,480
+ماهي ال function؟ دعنا نقول واحد بتعملنا حاجة
+
+84
+00:06:50,480 --> 00:06:53,760
+بنسميها protection لأنها covering لل skin خط
+
+85
+00:06:53,760 --> 00:06:56,760
+الدفاع الأول قلنا عن الجسم هو ال skin والمكون
+
+86
+00:06:56,760 --> 00:07:00,980
+الأساسي له هي ال epithelial cell يبقى protection
+
+87
+00:07:03,070 --> 00:07:08,330
+احنا كتير بنتعرض لإنه ممكن إنه يصير فينا abrasions
+
+88
+00:07:08,330 --> 00:07:11,850
+ممكن يصير mechanical compression على ال skin مين
+
+89
+00:07:11,850 --> 00:07:15,950
+اللي بيحمي ال skin هذا ال epithelial cells، كمان
+
+90
+00:07:15,950 --> 00:07:22,310
+ممكن يكون sensory، طب sensory كيف؟طبعا في خلايا ال
+
+91
+00:07:22,310 --> 00:07:27,370
+epithelial cell المبطنة مثلا لل nos بتعطيني إحساس
+
+92
+00:07:27,370 --> 00:07:33,490
+بال smell الخلايا المبطنة للسان ال epithelial cell
+
+93
+00:07:33,490 --> 00:07:38,210
+في اللسان بتخلينا نحس بخاصية اللي هي ال testing أو
+
+94
+00:07:38,210 --> 00:07:44,230
+التدوقموجودة في ال inner ear بتخلينا بتساعدنا على
+
+95
+00:07:44,230 --> 00:07:48,750
+التوازن و هكذا هذه المجموعة في الإحساس أحيانا بال
+
+96
+00:07:48,750 --> 00:07:52,430
+skin فيها receptors many receptors بتخلينا أننا
+
+97
+00:07:52,430 --> 00:07:57,690
+نشعر أو نحس بالأشياء مواصلات خلينا فيها تقول أو
+
+98
+00:07:57,690 --> 00:08:04,490
+receptors لجهاز العصبي كمان ال secretion secretion
+
+99
+00:08:05,540 --> 00:08:09,320
+top secretion إيش الإفراز؟ قولنا هذه الخلايا وين
+
+100
+00:08:09,320 --> 00:08:14,910
+موجودة؟ هي مبطنة للقنوات، قولنا هي موجودةفي
+
+101
+00:08:14,910 --> 00:08:20,710
+القنوات تبع الجسم القنوات هذه بتبقى على عبارة عن
+
+102
+00:08:20,710 --> 00:08:25,890
+إيش؟ قنوات الجهاز مثلا ال .. الهضمي الهضمي كله
+
+103
+00:08:25,890 --> 00:08:29,250
+بيمر فيها الطعام فهي بتفرز لو اتكلمنا عن القناة
+
+104
+00:08:29,250 --> 00:08:33,950
+الهضمية سواء المعدة سواء الأمعاء فهي بتفرز مواد
+
+105
+00:08:33,950 --> 00:08:38,270
+هاضمة أو عصارات هاضمة هذه وظيفتها بتكون وظيفة
+
+106
+00:08:38,270 --> 00:08:41,950
+الectelia السلسلية اللى تفرز هذه الأشياء وكمان لو
+
+107
+00:08:41,950 --> 00:08:46,080
+اتكلمنا عن ال intestine مثلاهي ال intestine فيها
+
+108
+00:08:46,080 --> 00:08:51,420
+خلايا بثيل يلسل بتساعد على ال secretion وكمان على
+
+109
+00:08:51,420 --> 00:08:56,280
+الانتصاص الانتصاص إيش يعني؟ الانتصاص إنه بتكون دخل
+
+110
+00:08:56,280 --> 00:09:01,120
+الطعام بعد عملية الهضم للقناع لل intestine بيصير
+
+111
+00:09:01,120 --> 00:09:04,720
+عملية الانتصاص في خلالها من خلالها اللي هي عملية
+
+112
+00:09:04,720 --> 00:09:10,280
+تبادل الأغضية عن طريق الدمexecration كمان كيف بنا
+
+113
+00:09:10,280 --> 00:09:14,660
+نخلص الجسم أو ال filtration وكيف بنا نخلص الجسم
+
+114
+00:09:14,660 --> 00:09:18,940
+كمان من المواد السامة اللي ممكن مثلا زي ال kidney
+
+115
+00:09:18,940 --> 00:09:23,380
+و ال kidney ducts كلها موجود فيها ال epithelial
+
+116
+00:09:23,380 --> 00:09:26,740
+cell حتى نقدر أو الخلايا اللي موجودة في الجسم اللي
+
+117
+00:09:26,740 --> 00:09:30,140
+هي التعرق احنا انسينا نقول حاجة ان ال epithelial
+
+118
+00:09:30,140 --> 00:09:37,780
+tissue عبارة عن نوعين بالشكل اه sorryإذا بنقدر
+
+119
+00:09:37,780 --> 00:09:42,820
+نقول في شكل membrane وفي
+
+120
+00:09:42,820 --> 00:09:50,960
+gland حسب تركبتها يعني membrane هذا يعني إنه هذا
+
+121
+00:09:50,960 --> 00:09:56,980
+الشكل في عندنا و هيك في عندنا خلايا و كلها هي
+
+122
+00:09:56,980 --> 00:10:00,300
+عبارة عن compact أو tightly
+
+123
+00:10:03,210 --> 00:10:08,410
+cells جنب بعض جنب بعض جنب بعض كتير قريبا عندنا
+
+124
+00:10:08,410 --> 00:10:12,010
+بنشوف بالرسم الأوضح يمكن أنا مش كتير شاطرة بالرسم
+
+125
+00:10:12,010 --> 00:10:16,970
+هي cells فيها نوا وجنب بعض وفيها basement هنا
+
+126
+00:10:16,970 --> 00:10:21,570
+عندنا هنشوف هذه بتبقى على شكل membrane لكن لو كانت
+
+127
+00:10:21,570 --> 00:10:26,730
+بهذا الشكل فبدها
+
+128
+00:10:26,730 --> 00:10:30,390
+تكون كأنها شكل glance
+
+129
+00:10:37,920 --> 00:10:45,740
+وهنا لنعتبر ان هو موجودة فهنا بدها تكون gland غداد
+
+130
+00:10:45,740 --> 00:10:53,220
+وهنا على شكل من brains طيب
+
+131
+00:10:53,220 --> 00:10:58,760
+نشوف ال characteristics ايش مميزاتها او خصائصها
+
+132
+00:10:58,760 --> 00:11:05,240
+هذه ال epithelial cells اول اشي انها
+
+133
+00:11:07,130 --> 00:11:12,250
+بتغطي كل أجزاء ال body بتغطي كل أجزاء ال body
+
+134
+00:11:12,250 --> 00:11:16,730
+فاحنا بنقول ال skin هو ال suit اللي بيبقى لبسها ال
+
+135
+00:11:16,730 --> 00:11:22,050
+body عشان تحمي بتلم كل الأشياء اللي موجودة under
+
+136
+00:11:22,050 --> 00:11:26,390
+the skin فهي covering ال body و covering ال organs
+
+137
+00:11:26,390 --> 00:11:27,570
+كمان نفسها
+
+138
+00:11:29,930 --> 00:11:34,390
+من أحد كمان وظيفة احنا قلنا في عندنا عدد من ال
+
+139
+00:11:34,390 --> 00:11:38,370
+cavities اللي موجودة في الجسم، في عندنا ال plural
+
+140
+00:11:38,370 --> 00:11:42,210
+cavity و ال cardiac cavity و عندنا الberitanium
+
+141
+00:11:42,210 --> 00:11:47,370
+اللي موجودة اللي هي في منطقة البطن و الأحشاء فهي
+
+142
+00:11:47,370 --> 00:11:53,930
+بتغطيها، بتبطمها كلهاوكمان الفتحات موجودة كلها في
+
+143
+00:11:53,930 --> 00:11:59,890
+الجسم بطبيعتها او ال ducts الموجودة في الجسم بتكون
+
+144
+00:11:59,890 --> 00:12:05,050
+مبطنة بال epithelial tissue طبعا إذا احنا بنشوف
+
+145
+00:12:05,050 --> 00:12:12,290
+الصورة هنا زي ما هو واضح هي في عندنا basement هنا
+
+146
+00:12:12,290 --> 00:12:20,550
+إلها قاعدة وكمان sorry إلها قاعدةوالها lateral
+
+147
+00:12:20,550 --> 00:12:24,530
+border اللي احنا شايفينه هنا والها apical surface
+
+148
+00:12:24,530 --> 00:12:29,050
+يعني لو احنا نضبحها بالصورة كل epithelial cell
+
+149
+00:12:29,050 --> 00:12:34,830
+موجودة في
+
+150
+00:12:34,830 --> 00:12:45,310
+تركبتها بيكون لها قاعدة أو basement وكمان في هنا
+
+151
+00:12:45,310 --> 00:12:47,570
+لو قلنا هذه الخلايا
+
+152
+00:12:49,550 --> 00:12:55,630
+جانب بعضها جانب بعضها مخدش شكل cubic تمام هان
+
+153
+00:12:55,630 --> 00:13:03,590
+إليها free end free end أو apical هان
+
+154
+00:13:03,590 --> 00:13:06,470
+في إليها هذا اسمه lateral
+
+155
+00:13:09,090 --> 00:13:13,070
+باردر وهنا لتحت بيكون basement ايش وظيفة ال
+
+156
+00:13:13,070 --> 00:13:16,830
+basement انها بتفصلها عن ال other underlying
+
+157
+00:13:16,830 --> 00:13:20,510
+connective tissue يعني بتكون شي مفصولة هي اللي
+
+158
+00:13:20,510 --> 00:13:24,650
+مابتكون على شكل membrane هنا و طبعا هنا فيها النوة
+
+159
+00:13:26,050 --> 00:13:29,710
+زي ما واضح بالرسم اللي على ال slides شايفين ال
+
+160
+00:13:29,710 --> 00:13:34,830
+placement اللي هي الطبقة السفلية ال lateral border
+
+161
+00:13:34,830 --> 00:13:38,790
+أو ال lateral surface هذا عبارة عن connective
+
+162
+00:13:38,790 --> 00:13:44,370
+tissue بتلاسق لإنها تالتلي packed tissue فلاي و
+
+163
+00:13:44,370 --> 00:13:48,330
+متلاسقة و متراسة فالتلاسق بيصير و التراس عن طريق
+
+164
+00:13:48,330 --> 00:13:52,610
+ال lateral surface وكمان عندنا ال free apical end
+
+165
+00:13:52,610 --> 00:13:58,480
+أو surfaceمن مميزاتها أيضًا إنها a-vascular يعني
+
+166
+00:13:58,480 --> 00:14:00,900
+الـepithelia اللي في الـcell فيش فيها
+
+167
+00:14:00,900 --> 00:14:08,200
+vascularization على الإطلاق أما فيها إحساس يعني
+
+168
+00:14:08,200 --> 00:14:15,360
+فيها nervous system بيوصلها أما هي also readily
+
+169
+00:14:15,360 --> 00:14:21,770
+dividedtightly packed متراسة متلاسقة جدا مع بعضها
+
+170
+00:14:21,770 --> 00:14:29,790
+فيها أحيانا مواد لاسقة dysmosiums classified
+
+171
+00:14:29,790 --> 00:14:35,950
+according to its shape and number and number of
+
+172
+00:14:35,950 --> 00:14:41,270
+layers إيش يعني لما بنيجي بنقسم ال epithelial cell
+
+173
+00:14:41,270 --> 00:14:46,590
+في عيننا نوعين من التقسيمات the classification
+
+174
+00:14:51,260 --> 00:14:59,280
+according to the number of layers أو
+
+175
+00:14:59,280 --> 00:15:09,180
+according of the shape shape
+
+176
+00:15:09,180 --> 00:15:12,180
+فينا تلت أنواع
+
+177
+00:15:15,030 --> 00:15:18,550
+مهد بنسميها الـ Squamous اللي هي عبارة عن إيش
+
+178
+00:15:18,550 --> 00:15:25,050
+شكلها بهذا الشكل هي ال basement وهيها هيك بيسموها
+
+179
+00:15:25,050 --> 00:15:30,170
+الخرشوفية بتبقى عاملة زي البيضة المقلية بهذا الشكل
+
+180
+00:15:30,170 --> 00:15:32,070
+هذه بنسميها Squamous
+
+181
+00:15:35,030 --> 00:15:41,510
+أما في خلايا تانية في شكلها عامل زي المكعب انا مش
+
+182
+00:15:41,510 --> 00:15:46,630
+كتير شاطرة بالرسم بس خلينا نقول هيك و هيك ويلها
+
+183
+00:15:46,630 --> 00:15:57,870
+قاعدة او هذه كيوبيت كيوبيك او شكلها على شكل column
+
+184
+00:15:57,870 --> 00:16:04,250
+هذا الشكل طويلة وهنا القاعدة كله من ال
+
+185
+00:16:07,820 --> 00:16:13,140
+طبعا هذا على حسب الشيء في أن تلت أنواع هذه هنشوفه
+
+186
+00:16:13,140 --> 00:16:21,620
+في التقسيمة تبعتها ل squamous ل cupoid and
+
+187
+00:16:21,620 --> 00:16:25,540
+incoluminal أما ال layer إذا كانت هي عبارة عن one
+
+188
+00:16:25,540 --> 00:16:34,280
+layer اعتبر أنه هذه cupoid cubic و كمان layerوكمان
+
+189
+00:16:34,280 --> 00:16:39,140
+layer لكن احنا بنسميها على حسب ال layer الأخير
+
+190
+00:16:39,140 --> 00:16:46,020
+فيها قعدنا هنشوف كيف شكل ال layer الأخير الموجود
+
+191
+00:16:46,020 --> 00:16:53,460
+هو احنا بنسميها يا اما اذا كانت مجموعة بنسميها
+
+192
+00:16:53,460 --> 00:17:02,230
+stratified اما اذا كانت one layer بهذا الشكلفهي
+
+193
+00:17:02,230 --> 00:17:09,210
+بتكون simple تمام؟
+
+194
+00:17:09,210 --> 00:17:12,390
+ان شاء الله نكون احنا يعني واضحنا شوية ولو ان
+
+195
+00:17:12,390 --> 00:17:17,530
+الرسم متواضع كتير بس هنشوف عيدنا على ال slide أوضح
+
+196
+00:17:21,000 --> 00:17:24,680
+طبعا covering and lining الابيثيليام ال epidermis
+
+197
+00:17:24,680 --> 00:17:28,160
+of the skin، lining ال blood vessels and duct، ال
+
+198
+00:17:28,160 --> 00:17:31,940
+respiratory و ال reproductive و ال urinary و في
+
+199
+00:17:31,940 --> 00:17:35,860
+منها النوع التاني اللي هي ال glandular اللي عاملة
+
+200
+00:17:35,860 --> 00:17:39,600
+على شكل إجلان وظيفتها تعمل secretion of the gland
+
+201
+00:17:39,600 --> 00:17:43,600
+زي الثيرويد و ال adrenaline و ال secreting إجلان
+
+202
+00:17:44,760 --> 00:17:48,380
+روحنا لل classification اللى تو احنا رسمناه فى
+
+203
+00:17:48,380 --> 00:17:54,020
+الخلف واضحناه ال squamous اللى هى هذه اول واحدة هى
+
+204
+00:17:54,020 --> 00:17:59,180
+عبارة عن خلايا حرشوفية شكلها عاملة بالثبات زى
+
+205
+00:17:59,180 --> 00:18:05,260
+البيضة المقلية صفر فى النص والبيض منتشر على فى
+
+206
+00:18:05,260 --> 00:18:12,920
+المقلة فهى عبارة عن خلاياالكيوبويد عاملة زي كأنها
+
+207
+00:18:12,920 --> 00:18:20,140
+مكعبات مترصة جانب بعضها طبقة واحدة فهي كيوبويد أما
+
+208
+00:18:20,140 --> 00:18:25,680
+الكولومينار فهي عبارة عن إيش؟أعمدة في القاعدة
+
+209
+00:18:25,680 --> 00:18:30,260
+تبعتها أو قريب من القاعدة موجودة انموها زي ما احنا
+
+210
+00:18:30,260 --> 00:18:35,040
+شايفينها هنا أما بالنسبة لل arrangement ال
+
+211
+00:18:35,040 --> 00:18:38,520
+classification التاني عدد الطبقات أو number of
+
+212
+00:18:38,520 --> 00:18:42,360
+layers في عندنا ال simple وفي عندنا ال stratified
+
+213
+00:18:42,360 --> 00:18:46,120
+وفي عندنا ال pseudo stratified طبعا هنا الصورة
+
+214
+00:18:46,120 --> 00:18:50,840
+المضحكة عندنا ال simple انها one layerعبارة عن one
+
+215
+00:18:50,840 --> 00:18:55,900
+layer أما الـ stratified فهي عندنا مجموعة من ال
+
+216
+00:18:55,900 --> 00:19:01,000
+layers من ال cells المختلفة لكن احنا عادة عندنا
+
+217
+00:19:01,000 --> 00:19:04,880
+هنشوف بنسميها بنسميها حسب الطبقة الأخيرة من ال
+
+218
+00:19:04,880 --> 00:19:10,540
+cells أما ال pseudo stratified فهي عبارةبالشكل أو
+
+219
+00:19:10,540 --> 00:19:14,800
+المنظر تبعها مثلا هي خلينا نقول ال basement هيو
+
+220
+00:19:14,800 --> 00:19:22,620
+تمام؟ في عندنا هنا مثلا سل و سل صغيرة و بعدين جاي
+
+221
+00:19:22,620 --> 00:19:26,920
+سل كبيرة هنا و بعدين سل صغيرة و بعدين سل كبيرة هنا
+
+222
+00:19:26,920 --> 00:19:30,520
+و يكونوا متلاسقة هادي مع هادي كمان بهذا الشكل
+
+223
+00:19:30,520 --> 00:19:37,660
+تمام؟ و هنا في سل و هنا في عنديالنواء وهنا النواء
+
+224
+00:19:37,660 --> 00:19:44,080
+تمام؟ طيب هذا الشكل اللي احنا شايفينه صغير وكبير
+
+225
+00:19:44,080 --> 00:19:50,660
+بيبينلي كأنها هي طبقات لكن هي في الحقيقة مش طبقات
+
+226
+00:19:50,660 --> 00:19:56,580
+هي عبارة عن طبقة خليني بس أورجيكم إياها على ال
+
+227
+00:19:56,580 --> 00:20:01,000
+slide تقريبا احنا في ال slide هذه موجودة
+
+228
+00:20:05,800 --> 00:20:09,440
+هنوصلها عندنا بلاش احنا نضيع كتير وقت فيها هي
+
+229
+00:20:09,440 --> 00:20:15,140
+عبارة قلنا عن إيش؟ عن شكلها و كأنها طبقية لكن هي
+
+230
+00:20:15,140 --> 00:20:21,180
+بالحقيقة مش طبقات هي عبارة عن one line لكن فيها سل
+
+231
+00:20:21,180 --> 00:20:23,540
+كبيرة وسل صغيرة
+
+232
+00:20:31,060 --> 00:20:35,520
+يبقى هنا سيمبل مستراتفايف و سودو كلمة سودو يعني
+
+233
+00:20:35,520 --> 00:20:42,060
+كاذب او بالعربي بتطلع false يعني سودو false
+
+234
+00:20:42,060 --> 00:20:51,500
+السيمبل ابثيلام تيشيو هي عبارة عن أربع أنواع سيمبل
+
+235
+00:20:51,500 --> 00:20:58,060
+squamous شكلها هرشوفي وطبقة line واحد سيمبل كيقاعد
+
+236
+00:20:58,860 --> 00:21:02,980
+and simple columnar وفي عندنا الـ pseudostratified
+
+237
+00:21:02,980 --> 00:21:06,060
+وكأن هو بيقول إنها stratified و مش stratified
+
+238
+00:21:06,060 --> 00:21:11,960
+فالحقيقة هي عبارة عن one line أو طبقة واحدة فيها
+
+239
+00:21:11,960 --> 00:21:17,720
+cells طويلة و cells قصيرة متراصة فبتيجي فبتبدأ
+
+240
+00:21:17,720 --> 00:21:21,820
+المكان ال wall موجودة فيها عشان هيك تطلع شكلها و
+
+241
+00:21:21,820 --> 00:21:26,840
+كإنها stratified طبقية أو طبقات ال epithelial
+
+242
+00:21:26,840 --> 00:21:31,230
+tissueالـ single squamous epithelial زي ما احنا
+
+243
+00:21:31,230 --> 00:21:35,230
+شايفينها بهذا الشكل هي في عندنا ال basement على
+
+244
+00:21:35,230 --> 00:21:38,350
+طول ال basement فصل ال epithelial cell عن ال
+
+245
+00:21:38,350 --> 00:21:42,110
+connective tissue و في نفس الوقت أعطانا الشكل اللي
+
+246
+00:21:42,110 --> 00:21:48,150
+احنا وصفناه قبل شوية عبارة عن طبقة واحدة من ال
+
+247
+00:21:48,150 --> 00:21:49,730
+cells
+
+248
+00:21:57,670 --> 00:22:04,030
+أما ال symbol squamous فهي موجودة وين؟ موجودة في
+
+249
+00:22:04,030 --> 00:22:07,890
+lining ال blood vessels و ال lymphatic vessels و
+
+250
+00:22:07,890 --> 00:22:15,610
+ال air sacs اللي هي ال alveoli single
+
+251
+00:22:15,610 --> 00:22:21,710
+layer of flat cells فهذه ال symbol squamous cell
+
+252
+00:22:21,710 --> 00:22:24,850
+زي ما احنا شايفينها بالصورة
+
+253
+00:22:26,300 --> 00:22:30,440
+هي أشكال مختلفة موجودة في أماكن مضبوعة .. الموضوع
+
+254
+00:22:30,440 --> 00:22:35,100
+ال .. بين موجودة simple squamous فما إحنا شايفينها
+
+255
+00:22:35,100 --> 00:22:41,420
+بالرسم الموضع حوالين
+
+256
+00:22:41,420 --> 00:22:45,100
+البريتانيا أو ال abdominal cavity
+
+257
+00:22:48,360 --> 00:22:53,940
+أما الـ simple cuboid أو cuboidal cell فهذا شكلها
+
+258
+00:22:53,940 --> 00:22:57,100
+عبارة عن طبقة متراسة هي عندنا ال connective tissue
+
+259
+00:22:57,100 --> 00:23:01,820
+و عندنا ال basement هنا شكل المكعب للخلية و هنا
+
+260
+00:23:01,820 --> 00:23:03,620
+النوع
+
+261
+00:23:06,580 --> 00:23:10,700
+طبعا إيش وظيفتها؟ مانوجودة .. موجودة في ال kidney
+
+262
+00:23:10,700 --> 00:23:16,500
+tubes، ال ovaries، some of the gland هي عبارة عن
+
+263
+00:23:16,500 --> 00:23:21,860
+simple أو one layer of cube shared cells
+
+264
+00:23:24,860 --> 00:23:30,180
+و هدا إحدى الأشكال هي حاططنا في ال pancreas كيف
+
+265
+00:23:30,180 --> 00:23:36,560
+شكلها و كيف بتكون تركبتها و هي عبارة عن one layer
+
+266
+00:23:36,560 --> 00:23:42,620
+of occupied cells أما
+
+267
+00:23:42,620 --> 00:23:47,440
+ال columnar فهي زي ما هي موضحة بالشكل زي ما إحنا
+
+268
+00:23:47,440 --> 00:23:56,110
+شايفين في عندنا هي basement وهي في عندناالـ C وفي
+
+269
+00:23:56,110 --> 00:24:00,470
+الغالب بيكون فيه سيليا أو أهداب موجودة أو زغب ما
+
+270
+00:24:00,470 --> 00:24:03,910
+نسميه احنا الزغب يبقى بقى a single layer of
+
+271
+00:24:03,910 --> 00:24:08,290
+elongated cells للـ nuclei usually near the
+
+272
+00:24:08,290 --> 00:24:12,950
+basement عادة بتكون قريبة من ال basementof the
+
+273
+00:24:12,950 --> 00:24:17,770
+membrane sometimes بتكون في عندها في نهاياتها حاجة
+
+274
+00:24:17,770 --> 00:24:21,710
+اسمها السيليا ما بنسميها احنا الأهداب وكمان ممكن
+
+275
+00:24:21,710 --> 00:24:24,890
+يكون حاجة اسمها ال microvilli الزغب اللي احنا
+
+276
+00:24:24,890 --> 00:24:29,010
+بنتكلم عنه بنقول عنه الزغب ان هي شعيرات صغيرة كتير
+
+277
+00:24:29,370 --> 00:24:33,670
+often have goblets cells زي عاملة بعض ال cells
+
+278
+00:24:33,670 --> 00:24:38,250
+اللي عاملة زي جيوب أو زي الكؤوس خلينا نسميها
+
+279
+00:24:38,250 --> 00:24:43,110
+موجودة في ال ureterus و ال stomach و ال intestine
+
+280
+00:24:43,110 --> 00:24:50,710
+و هذا شكلها كيف بتكون موجودة بالخلية و اذا احنا
+
+281
+00:24:50,710 --> 00:24:57,250
+بتطلعنا على ال goblets اللي موجودة بهذا المكان
+
+282
+00:25:02,550 --> 00:25:07,610
+السنب الكولومير و ال سيليا هى احنا شايفينها زى
+
+283
+00:25:07,610 --> 00:25:17,450
+موجودة فى القناة تلوب او فى الورينالى tubes او فى
+
+284
+00:25:17,450 --> 00:25:22,670
+الوتراين tubes هذا
+
+285
+00:25:22,670 --> 00:25:27,510
+الى علاقة بموضوع التطبيق وخروج البويضة واستقطاب
+
+286
+00:25:27,510 --> 00:25:32,030
+الحيوان ما نقولها كده عشان هي كتفيها السيليا
+
+287
+00:25:36,230 --> 00:25:42,510
+أما الـ Sodostratified Ciliated Epithelium هي
+
+288
+00:25:42,510 --> 00:25:47,250
+عبارة عن single layer of elongated سل طويلة زي ما
+
+289
+00:25:47,250 --> 00:25:52,410
+احنا وضحناها بالرسم وكمان موجود فيها نواة بس مش
+
+290
+00:25:52,410 --> 00:25:58,920
+على نفس المستوىممكن تكون الـwa في ال base and
+
+291
+00:25:58,920 --> 00:26:05,900
+above أبير استرياتي تطلع فيها فكرها استرياتي دائما
+
+292
+00:26:05,900 --> 00:26:09,360
+أو غالبا تكون فيها السيليا اللي هي الأهداب وال
+
+293
+00:26:09,360 --> 00:26:13,650
+goblet cellsتاقما بتكون موجودة في ال respiratory
+
+294
+00:26:13,650 --> 00:26:17,510
+pathway احنا بنفهم ان وجود السيلي عشان تساعد على
+
+295
+00:26:17,510 --> 00:26:21,970
+عملية ال expectoration اللى ممكن تساعد على خروج ال
+
+296
+00:26:21,970 --> 00:26:25,950
+mucus او ال excessive mucus او ال unwanted mucus
+
+297
+00:26:25,950 --> 00:26:29,030
+اللى موجود في ال respiratory tract
+
+298
+00:26:32,980 --> 00:26:37,100
+وهذا القراصان التاني بيوضح موجود الـ Sodium
+
+299
+00:26:37,100 --> 00:26:41,800
+stratified epithelia موجود في التراكيا لأنه دايما
+
+300
+00:26:41,800 --> 00:26:44,200
+بيحتوي على الأهداف اللي ساعد على عملية الـ
+
+301
+00:26:44,200 --> 00:26:49,560
+expectorationأما الـ Stratified اللي احنا بنسميها
+
+302
+00:26:49,560 --> 00:26:53,840
+الطبقية أو المجموعة يعني according ال
+
+303
+00:26:53,840 --> 00:26:56,300
+classification according to the number of number
+
+304
+00:26:56,300 --> 00:27:01,320
+of layers فعنا ال Stratified squamous و Stratified
+
+305
+00:27:01,320 --> 00:27:06,960
+cuboid وعنا ال Stratified columnar يعني نفس مواعي
+
+306
+00:27:06,960 --> 00:27:13,800
+الخلايا لكن مكونة من عدة طبقات وهذا
+
+307
+00:27:16,080 --> 00:27:20,860
+مظهر أو خلّينا نقول رسم توضيحي Gestratified
+
+308
+00:27:20,860 --> 00:27:25,520
+Squamous اللي هي الحرشوفية لكن الطبقية many cells
+
+309
+00:27:25,520 --> 00:27:29,300
+of layer top cell are flat لإن احنا عادة لما
+
+310
+00:27:29,300 --> 00:27:32,440
+بنسميها بنسمي في الطبقة الأخيرة مانظرش للطبقات
+
+311
+00:27:32,440 --> 00:27:36,680
+التانية في الطبقة الأخيرة الشكلة فبنسمي السلب هذا
+
+312
+00:27:36,680 --> 00:27:41,980
+الشكل top cell are flat can accumulate keratin إيش
+
+313
+00:27:41,980 --> 00:27:46,550
+يعني keratin؟ فيه protein في الجسم اسمه keratinهذا
+
+314
+00:27:46,550 --> 00:27:53,030
+في خلايا لكن ميتة أو خلايا مافيش فيها نوعهذه
+
+315
+00:27:53,030 --> 00:27:59,230
+بتتكون ال outer layer of the skin وكمان ال oral
+
+316
+00:27:59,230 --> 00:28:03,470
+cavity و ال vagina و ال anal canal طبعا هذه
+
+317
+00:28:03,470 --> 00:28:07,230
+وظيفتها الخلايا اللي فيها الكيروتينية بتساعد على
+
+318
+00:28:07,230 --> 00:28:11,690
+shock absorption بتساعد على ال .. هذه بيسميها احنا
+
+319
+00:28:11,690 --> 00:28:16,670
+خلايا ميتة بتخفف الصدمات على ال skin أو على
+
+320
+00:28:16,670 --> 00:28:18,130
+الأماكن هذه
+
+321
+00:28:22,970 --> 00:28:27,070
+هذا شكل من الـ stratified squamous موجود في ال
+
+322
+00:28:27,070 --> 00:28:33,490
+vagina اما
+
+323
+00:28:33,490 --> 00:28:38,070
+الكيوبويت two to three layers of cube-shaped cells
+
+324
+00:28:38,070 --> 00:28:41,330
+line the ducts of mammary gland، الممر اللي هي
+
+325
+00:28:41,330 --> 00:28:46,010
+خلايا الثدية، sweating gland، salivary gland اللي
+
+326
+00:28:46,010 --> 00:28:50,180
+هي بتفرز اللعاب و كذلك ال pancreasزي ما احنا
+
+327
+00:28:50,180 --> 00:28:55,340
+شايفينها بالصورة مجموعة من الـ cubic أو الـ
+
+328
+00:28:55,340 --> 00:29:00,400
+cuboidal cells لكن أكتر من طبقة و طبعا هذا عادة
+
+329
+00:29:00,400 --> 00:29:04,280
+الرسم بعيد و بيزيد بإن في عندنا ال basement اللي
+
+330
+00:29:04,280 --> 00:29:07,940
+بيفصل ال connective tissue عن ال cells و في شايفين
+
+331
+00:29:07,940 --> 00:29:11,960
+ال end هنا ال abical surfaceهنا و في كمان في ال
+
+332
+00:29:11,960 --> 00:29:15,360
+borders هذه او ال lateral borders اللي بيكون
+
+333
+00:29:15,360 --> 00:29:20,340
+بيحتوي على المواد اللاسقة اللي بتخليها tightly
+
+334
+00:29:20,340 --> 00:29:27,000
+closed او packed tissue في
+
+335
+00:29:27,000 --> 00:29:31,860
+عندنا ال stratified Q-Border الابيتيليام اللي
+
+336
+00:29:31,860 --> 00:29:38,430
+موجودة في ال Oesophagus وهذا شكلهاأما ال columnar
+
+337
+00:29:38,430 --> 00:29:43,490
+فهي عبارة عن stratified columnar بنفس الطريقة اللي
+
+338
+00:29:43,490 --> 00:29:47,010
+احنا بنتكلم عنها ان هي عبارة عن مجموعة من الطبقات
+
+339
+00:29:47,010 --> 00:29:49,650
+احنا بنطلع على الطبقة الأخيرة زي ما احنا شايفين
+
+340
+00:29:49,650 --> 00:29:54,790
+كيف شكل الطبقة الأخيرة فهي شكلها طولي أو عمودية
+
+341
+00:29:54,790 --> 00:29:58,710
+فبنسميها stratified columnar
+
+342
+00:30:01,090 --> 00:30:05,410
+بتكون الطبقة الخارجية مخدة شكل ال column اما
+
+343
+00:30:05,410 --> 00:30:09,570
+الطبقات التانية مخدة شكل look the pipe line part
+
+344
+00:30:09,570 --> 00:30:17,870
+of male urethra and part of pharynx وهذا رسم
+
+345
+00:30:17,870 --> 00:30:23,630
+توضيحي في حاجة اسمها transitional طب ال
+
+346
+00:30:23,630 --> 00:30:31,200
+transitional هذهليش اتسمت هيك؟ Transitional انها
+
+347
+00:30:31,200 --> 00:30:38,540
+many cell layers, cubic shape and elongated cell
+
+348
+00:30:38,540 --> 00:30:43,440
+هذه ليش اتسمت هيك؟ اتكلم عن احنا مثلا عن البلدر
+
+349
+00:30:43,440 --> 00:30:47,080
+البلدر بتحتوي على ال urine البلدر لما بيكون فش
+
+350
+00:30:47,080 --> 00:30:51,380
+فيها urine بتكون صغيرة طبعا فبيكون شكل ال cell
+
+351
+00:30:51,380 --> 00:30:55,560
+فيها columnar بهذا الشكل
+
+352
+00:31:15,400 --> 00:31:21,340
+تمام؟ تمام؟ تمام؟
+
+353
+00:31:21,340 --> 00:31:24,780
+تمام؟ تمام؟ تمام؟
+
+354
+00:31:41,530 --> 00:31:48,050
+تخيلوا شغالة لما بتنشد بتنشد زي ال blooder ال
+
+355
+00:31:48,050 --> 00:31:51,270
+blooder لما تكون full of urine بتنشد فبصير شكل
+
+356
+00:31:51,270 --> 00:31:56,230
+الخلايا فيها كده cubic تمام لما بيروح الضغط بصير
+
+357
+00:31:56,230 --> 00:32:04,210
+شكلها عمودي فهي بتحتوي على هذا النوع من ال cells
+
+358
+00:32:04,210 --> 00:32:08,330
+lining ال blooder و ال urethra and urethra
+
+359
+00:32:22,500 --> 00:32:28,440
+أما الـ glandular Epithelium composed of cell that
+
+360
+00:32:28,440 --> 00:32:33,320
+specialized to produce and secretes substance يبقى
+
+361
+00:32:33,320 --> 00:32:39,040
+احنا في عندنا secretion وكمان بيبقى production ل
+
+362
+00:32:39,040 --> 00:32:46,260
+ال hormones زي ال endocrine، glans وفي عندنا ال
+
+363
+00:32:46,260 --> 00:32:52,080
+exocrine، glans ال endocrine مافيش فيها ducts
+
+364
+00:32:54,470 --> 00:32:58,650
+and secret their product directly into the
+
+365
+00:32:58,650 --> 00:33:02,250
+interstitial fluid and blood stream لأن هي عبارة
+
+366
+00:33:02,250 --> 00:33:06,850
+عن hormone داخلية endocrine داخلية اتكلم عن ال
+
+367
+00:33:06,850 --> 00:33:11,090
+exocrine اللي هي الخارجية هذه ليش lack of duct
+
+368
+00:33:11,090 --> 00:33:14,490
+مافيش فيها قنوات لأن هي بتفرز في blood stream
+
+369
+00:33:14,490 --> 00:33:19,030
+مباشرة و تفرز في ال interstitial fluid مباشرة فهي
+
+370
+00:33:19,030 --> 00:33:25,440
+مافيش فيها ducts سماءطيب ال hormones عبارة عن أيه؟
+
+371
+00:33:25,440 --> 00:33:28,860
+هي عبارة عن مواد كيميائية بيفرزها .. بيفرزها ..
+
+372
+00:33:28,860 --> 00:33:33,560
+بتفرزها هذه ال gland حتى تنظم الجسم، تعمل حالة من
+
+373
+00:33:33,560 --> 00:33:38,120
+ال hemostasis، تضام الجسم أو توازن الجسم، التوازن
+
+374
+00:33:38,120 --> 00:33:41,880
+الداخلي والتوازن الخارجي، هذا ال .. ال .. ال .. ال
+
+375
+00:33:41,880 --> 00:33:45,550
+Indo وال Exocrine system بالضبطخلّينا نقول أو الـ
+
+376
+00:33:45,550 --> 00:33:48,970
+endocrine system هو اللي بيتحكم فيه فالـ hormones
+
+377
+00:33:48,970 --> 00:33:52,950
+عبارة عن إيه؟ chemical messengers to influence
+
+378
+00:33:52,950 --> 00:33:56,930
+cell activity elsewhere in the body يعني ممكن هي
+
+379
+00:33:56,930 --> 00:34:01,910
+بتفرز من مكان لكن بتكون تأثيرها في أماكن تانية على
+
+380
+00:34:01,910 --> 00:34:05,270
+الجسم عشان هي بتفرز في blood steam نفسه في الـ
+
+381
+00:34:05,270 --> 00:34:09,330
+interstitial effluent أما الـ exocrine هي أخر
+
+382
+00:34:11,570 --> 00:34:14,510
+محاضرتنا لليوم مش هنكون مطولانش عليكوا الـ
+
+383
+00:34:14,510 --> 00:34:17,890
+Exocrine اللي هو الإفراز الخارجي Maintain their
+
+384
+00:34:17,890 --> 00:34:21,430
+contact with the epithelial surface by means of
+
+385
+00:34:21,430 --> 00:34:24,730
+duct يعني ال Exocrine فيها duct أما ال Endocrine
+
+386
+00:34:24,730 --> 00:34:27,670
+مافيش فيها duct لأنها بتفرز في بلد steam نفسها
+
+387
+00:34:27,670 --> 00:34:35,130
+وهذه بتروح عن طريق قنوات عشان تطلعها للخارجsecrets
+
+388
+00:34:35,130 --> 00:34:38,870
+materials onto the surface of the skin or onto the
+
+389
+00:34:38,870 --> 00:34:44,710
+epithelial surface lining and internal passageway
+
+390
+00:34:45,920 --> 00:34:49,080
+ننهي محاضرتنا لليوم عشان الأسبوع اللي جاي ان شاء
+
+391
+00:34:49,080 --> 00:34:52,420
+الله يكون أو يوم الأتنين أسبوع هذا ان شاء الله
+
+392
+00:34:52,420 --> 00:34:56,320
+يكون محاضرة عن باقى ال classifications تبع ال
+
+393
+00:34:56,320 --> 00:34:59,760
+tissue ال connective tissue و ال muscle tissue و
+
+394
+00:34:59,760 --> 00:35:04,240
+ال nerve tissue و يعطيكم على القافية السلام عليكم
+
+395
+00:35:04,240 --> 00:35:05,060
+و رحمة الله
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4.srt
new file mode 100644
index 0000000000000000000000000000000000000000..297e60abe14930644d1c1aff133e01aa4515acec
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4.srt
@@ -0,0 +1,1174 @@
+1
+00:00:04,930 --> 00:00:07,310
+باسم الله الرحمن الرحيم والصلاة والسلام علي سيدنا
+
+2
+00:00:07,310 --> 00:00:11,430
+محمد سيد المرسلين وعلى آله وصحبه أجمعين طبعا
+
+3
+00:00:11,430 --> 00:00:17,070
+اليوم هنستكمل في مساق التشريح في الـ skeletal
+
+4
+00:00:17,070 --> 00:00:19,790
+system، الجزء الثالث، هنتكلم عن الـ appendicular
+
+5
+00:00:19,790 --> 00:00:23,010
+system، واليوم أنا اخترت أن يكون معنا الـ skeleton
+
+6
+00:00:23,010 --> 00:00:26,850
+عشان نراجع الـ axial skeleton وبالتالي ننزل للـ
+
+7
+00:00:26,850 --> 00:00:32,790
+appendicular skeleton. الحقيقة إحنا حكينا أنه الـ
+
+8
+00:00:32,790 --> 00:00:36,450
+axial skeleton بتكون من الـ head والـ neck والـ
+
+9
+00:00:36,450 --> 00:00:41,490
+vertebral column والـ... الـ rib cage يعني أو الـ
+
+10
+00:00:41,490 --> 00:00:45,530
+trunk. هنا إحنا بنسميه الـ trunk، وقلنا أنه موجود على
+
+11
+00:00:45,530 --> 00:00:50,630
+الـ axial skeleton. موجود عندنا الـ pectoral girdle والـ
+
+12
+00:00:50,630 --> 00:00:54,030
+عندنا الـ pelvic girdle اللي بيكونوا مكون أساسي
+
+13
+00:00:54,030 --> 00:00:57,630
+لمحاضرتنا اليوم، اللي هي الـ appendicular system اللي
+
+14
+00:00:57,630 --> 00:01:01,210
+هو بيتكون من الـ upper limb والـ lower limb مع الـ
+
+15
+00:01:01,210 --> 00:01:05,580
+pectoral girdle والـ pelvic girdle. طبعا إحنا شايفين
+
+16
+00:01:05,580 --> 00:01:09,040
+إنه قدامنا، زي ما إحنا شايفين في الـ skeleton، لو
+
+17
+00:01:09,040 --> 00:01:14,080
+أجينا أخدنا هذا الـ... الـ lateral view، فبنلاقي إنه في
+
+18
+00:01:14,080 --> 00:01:18,720
+عندنا الـ neck، الـ head، وفي عندنا lordosis ناحية الـ
+
+19
+00:01:18,720 --> 00:01:23,080
+cervical column، وعندنا kyphosis ناحية... إذا نرجع
+
+20
+00:01:23,080 --> 00:01:25,980
+شوية للمحاضرة اللي فاتت، kyphosis من ناحية الـ
+
+21
+00:01:25,980 --> 00:01:30,960
+thoracic، وفي عندنا الـ lordosis على الـ lumbar، وفي
+
+22
+00:01:30,960 --> 00:01:37,420
+عندنا الـ sacrum and coccyx، وطبعا على الـ rib cage
+
+23
+00:01:37,420 --> 00:01:41,800
+موجود عندنا الـ scapula and clavicle اللي بترتبِط
+
+24
+00:01:41,800 --> 00:01:45,500
+فيهم الـ upper limb، وكذلك عندنا الـ pelvic bone
+
+25
+00:01:45,500 --> 00:01:51,490
+اللي بتعطيني ارتباط مع الـ lower extremity. هذا
+
+26
+00:01:51,490 --> 00:01:55,470
+بالنسبة للـ axial skeleton. لو جينا لمكونات الـ
+
+27
+00:01:55,470 --> 00:01:59,850
+appendicular skeleton، فبناخد في الـ upper part هذا،
+
+28
+00:01:59,850 --> 00:02:03,170
+بنسميه إحنا الـ non-weight bearing part، في عندنا الـ
+
+29
+00:02:03,170 --> 00:02:07,750
+scapula and clavicle، مكون للـ pectoral girdle والـ
+
+30
+00:02:07,750 --> 00:02:10,990
+upper limb. أنا هشرح اليوم بسرعة عشان إحنا نرجع للـ
+
+31
+00:02:10,990 --> 00:02:15,530
+slide اللي معنا. في عندنا الـ upper limb، فيها عدد من
+
+32
+00:02:15,530 --> 00:02:23,620
+العظام، بتتكون من عظم الـ humerus، في عندنا الـ radius،
+
+33
+00:02:23,620 --> 00:02:27,780
+العظمة المتحركة اللي بتعمل دوران، وفي عندنا الـ ulna
+
+34
+00:02:27,780 --> 00:02:32,640
+بتعمل articulation مع الـ wrists، في عندنا الـ eight
+
+35
+00:02:32,640 --> 00:02:37,060
+carpal bones، في عندنا first row أربع، second row
+
+36
+00:02:37,060 --> 00:02:44,160
+أربع، في عندنا الـ metacarpals، وعندنا الـ phalanges طبعا
+
+37
+00:02:44,160 --> 00:02:47,060
+إحنا بنعرف إنه في عندنا عدد الـ phalanges في الأربع
+
+38
+00:02:47,060 --> 00:02:51,980
+fingers. موجود في الـ thumb في عندنا two phalanges،
+
+39
+00:02:51,980 --> 00:02:55,960
+وفي الأربع أصابع الثانيين في عندنا three phalanges،
+
+40
+00:02:55,960 --> 00:02:59,980
+نفس التركيب هذا، ونفس العدد تقريبا يعني عدد مُقارب من
+
+41
+00:02:59,980 --> 00:03:04,080
+العظام. موجود عندنا مشابه له في الـ lower limb بس
+
+42
+00:03:04,080 --> 00:03:08,680
+هنا الـ lower limb، العظام أطول شوية يعني
+
+43
+00:03:08,680 --> 00:03:13,260
+قوتها أكبر، ليش؟ لأنها weight bearing bones، المعنى
+
+44
+00:03:13,260 --> 00:03:16,840
+أنه إحنا لما بنوقف بنوقف على أقدام الـ lower limb.
+
+45
+00:03:18,030 --> 00:03:24,770
+الـ pelvic girdle هو موجود، عبارة عن عظام الـ ilium والـ ischium مع
+
+46
+00:03:24,770 --> 00:03:29,930
+الـ pubis، بيتلحموا مع الـ sacrum في الخلف. هنا بيكونوا
+
+47
+00:03:29,930 --> 00:03:34,170
+خلينا نقول حوض، بتكون في الـ anterior part في الـ
+
+48
+00:03:34,170 --> 00:03:37,070
+upper pelvic، موجود فيه عندنا الـ abdominal viscerals،
+
+49
+00:03:37,070 --> 00:03:40,210
+وفي الـ lower part فيه عندنا الـ genitalia، وكمان
+
+50
+00:03:40,210 --> 00:03:44,010
+بيصير فيه عندنا attachment، لأن الوزن بينزل من الرأس
+
+51
+00:03:44,010 --> 00:03:47,950
+للـ cervical، وبروح على الـ trunk، وبجي على الـ
+
+52
+00:03:47,950 --> 00:03:52,370
+lumbar، وبيصير له توزيع على الـ both pelvic bones.
+
+53
+00:03:52,370 --> 00:03:56,230
+تمام؟ وبعدها بينزل على الـ lower limbs، وإحنا الـ
+
+54
+00:03:56,230 --> 00:04:00,290
+contact مع الأرض بيكون عندنا الـ foot. طبعا في عندنا
+
+55
+00:04:00,290 --> 00:04:04,570
+الـ longest والـ biggest bone in the body، زي الـ...
+
+56
+00:04:04,570 --> 00:04:08,810
+اللي هي الـ femur، وفي إنه كذلك بنحاول إنه... أن...
+
+57
+00:04:08,810 --> 00:04:13,570
+أن... أن... نُحط قدامنا الـ lower limb. في عندنا في الـ
+
+58
+00:04:13,570 --> 00:04:16,390
+anterior part of the knee، في عندنا sesamoid bone
+
+59
+00:04:16,390 --> 00:04:19,370
+اللي تسمى الـ patella، في الـ anterior part of the
+
+60
+00:04:19,370 --> 00:04:23,050
+knee، وفي عندنا الـ tibia والـ fibula. هذا هنشرح
+
+61
+00:04:23,050 --> 00:04:27,510
+مكوناتها على الصورة. الـ tibia والـ fibula، إحنا
+
+62
+00:04:27,510 --> 00:04:29,970
+قلنا هنا في... قلنا في radius، لكن في عندنا في lower
+
+63
+00:04:29,970 --> 00:04:32,980
+limb في عندنا الـ tibia والـ fibula. التيبيا هي الـ
+
+64
+00:04:32,980 --> 00:04:35,600
+weight bearing bone، أما الـ fibula، it is a non-weight
+
+65
+00:04:35,600 --> 00:04:38,980
+bearing bone، بتلتحم هدول عن طريق الـ ankle joint
+
+66
+00:04:38,980 --> 00:04:43,080
+مع الـ talus، مع الـ... carpal، الـ tarsal، هلقيت باختلف
+
+67
+00:04:43,080 --> 00:04:46,520
+اللفظ، بنقول عنها tarsal bones، في عندنا اللي هي الـ
+
+68
+00:04:46,520 --> 00:04:50,540
+bones، اللي هي الـ calcaneus والـ talus، وفي عندنا الـ
+
+69
+00:04:50,540 --> 00:04:53,300
+metatarsals.
+
+70
+00:04:53,940 --> 00:04:58,140
+وفي عندنا الـ phalanges، وهذه برضه نفس تقسيمات الـ upper
+
+71
+00:04:58,140 --> 00:05:02,760
+limb. هنتعرف عليهم واحدة واحدة من خلال محاضرتنا
+
+72
+00:05:02,760 --> 00:05:09,930
+لليوم. طيب، نشوف إيش؟ في عندنا على الـ slides اليوم
+
+73
+00:05:09,930 --> 00:05:15,590
+هنتكلم عن الـ appendicular system، اللي هو في الـ
+
+74
+00:05:15,590 --> 00:05:18,570
+upper part of the body، الـ pectoral girdle
+
+75
+00:05:18,570 --> 00:05:22,150
+attached to the upper limb to the trunk، والـ pelvic
+
+76
+00:05:22,150 --> 00:05:25,990
+girdle، زي ما وضحنا، attached lower limb. upper and
+
+77
+00:05:25,990 --> 00:05:29,110
+lower limbs differ in function، لكن هما بيختلفوا في
+
+78
+00:05:29,110 --> 00:05:33,430
+الوظيفة. قلنا الإيد عشان إحنا نقدر نتناول الأشياء و
+
+79
+00:05:33,430 --> 00:05:37,590
+نتحرك، وناكل، ونشرب، ونمشط، ونلبس، أما الرجل، الـ two
+
+80
+00:05:37,590 --> 00:05:42,650
+lower limbs، هما بي... مسئولين عن عملية الـ
+
+81
+00:05:42,650 --> 00:05:44,650
+ambulation والمشي.
+
+82
+00:05:46,890 --> 00:05:50,590
+الـ articulation of the pectoral girdle، زي ما
+
+83
+00:05:50,590 --> 00:05:55,190
+إحنا شايفين، في عندنا الـ clavicle هنا، وفي عندنا الـ
+
+84
+00:05:55,190 --> 00:06:00,130
+scapula. الـ clavicle مع الـ scapula، في عندنا joint
+
+85
+00:06:00,130 --> 00:06:06,540
+اسمه acromioclavicular joint، ومع الـ sternum هنا اللي
+
+86
+00:06:06,540 --> 00:06:11,720
+هي عظمة القص، فيه sternoclavicular joint. تمام؟ وفي
+
+87
+00:06:11,720 --> 00:06:15,380
+عندنا هنا في نهاية، في الـ lateral part، في عندنا
+
+88
+00:06:15,380 --> 00:06:19,480
+حاجة اسمها الـ glenoid cavity، بتصير تعمل
+
+89
+00:06:19,480 --> 00:06:23,320
+articulation مع الـ head of the humerus.
+
+90
+00:06:27,990 --> 00:06:32,030
+طبعا زي ما وضحنا، الـ upper extremity consists of
+
+91
+00:06:32,030 --> 00:06:35,330
+bones of the shoulder girdle, upper arm, lower
+
+92
+00:06:35,330 --> 00:06:39,530
+arm, wrist and hand. shoulder girdle made up of
+
+93
+00:06:39,530 --> 00:06:43,110
+scapula and clavicle، زي ما إحنا وضحنا هنا. الـ
+
+94
+00:06:43,110 --> 00:06:49,630
+clavicle forms only bony joint with the trunk، أما
+
+95
+00:06:49,630 --> 00:06:53,990
+الـ sternum، بنسمي الـ sternoclavicular joint، لكن الـ...
+
+96
+00:06:53,990 --> 00:06:57,030
+الـ scapula ما فيش joint مع الـ trunk. الـ scapula
+
+97
+00:06:57,030 --> 00:07:01,250
+محطوطة... حط يعني زي شنكل كده، عاملة... الـ scapula مع الـ
+
+98
+00:07:01,250 --> 00:07:06,690
+clavicle، ومحطوطين كده زي القلقة على الـ trunk. فالـ
+
+99
+00:07:06,690 --> 00:07:11,070
+scapula، حقيقة ما فيش joint. الـ joint الوحيد اللي موجود
+
+100
+00:07:11,070 --> 00:07:17,430
+فيها هنا مع الـ... الـ... الـ acromioclavicular joint.
+
+101
+00:07:17,430 --> 00:07:21,370
+وهذا الـ joint أصلا مع الـ upper limb، بعيد عن الـ
+
+102
+00:07:21,370 --> 00:07:26,410
+trunk. الـ
+
+103
+00:07:26,410 --> 00:07:30,730
+pectoral girdle
+
+104
+00:07:30,730 --> 00:07:34,110
+اللي هو مكوناته الأساسية الـ clavicle أو الـ scapula،
+
+105
+00:07:34,110 --> 00:07:38,790
+وهو طبيعته بيعمل support على الـ upper limb.
+
+106
+00:07:44,990 --> 00:07:50,250
+هذه شرحناها. نروح للـ power point اللي عندنا، نوضح
+
+107
+00:07:50,250 --> 00:07:56,210
+على... زي ما هو موضح على الرسم. نقلب، ناخد صورة خلفية
+
+108
+00:07:56,210 --> 00:08:00,170
+لأن الـ scapula ما فيش إمكانية إلا ننظر إليها إلا من
+
+109
+00:08:00,170 --> 00:08:04,250
+الخلف. فهنا بنلاحظ أن الـ scapula، مكوناتها فيها
+
+110
+00:08:04,250 --> 00:08:08,250
+spine، بينتهي بالـ acromion process هذا، وفيها
+
+111
+00:08:08,250 --> 00:08:13,250
+infraspinous fossa، وفيها supraspinous
+
+112
+00:08:13,250 --> 00:08:17,450
+fossa هنا، وهذه بتعطي attachment للعضلات. هنا الـ
+
+113
+00:08:17,450 --> 00:08:21,150
+medial border، وفي هنا الـ apex، وفي هنا الـ lateral
+
+114
+00:08:21,150 --> 00:08:26,850
+border of the scapula اللي بيروح بيوصل لـ... بيعمل
+
+115
+00:08:26,850 --> 00:08:29,750
+اللي بيكون لي في الـ lateral part، اللي هي الـ glenoid
+
+116
+00:08:29,750 --> 00:08:36,530
+cavity، اللي بتعمل attachment مع الـ... الـ humerus. في
+
+117
+00:08:36,530 --> 00:08:40,350
+حاجة اسمها coracoid process، زي إحنا شايفينه بهذا
+
+118
+00:08:40,350 --> 00:08:45,050
+المظهر هنا، وهذا وظيفته برضه بيعمل لي muscular
+
+119
+00:08:45,050 --> 00:08:53,950
+attachment. أما
+
+120
+00:08:53,950 --> 00:09:00,230
+الـ... الـ arm and forearm and the hand بتكونوا
+
+121
+00:09:00,230 --> 00:09:07,940
+تقريبا من thirty bones، ثلاثين عظمة، زي ما إحنا وضحنا
+
+122
+00:09:07,940 --> 00:09:11,440
+قبل كده. humerus، radius and ulna and carpal bones
+
+123
+00:09:11,440 --> 00:09:17,200
+and metacarpals and phalanges. تم. الـ humerus من
+
+124
+00:09:17,200 --> 00:09:22,580
+صفاتها إنها long bone، وهي تقريبا the longest of
+
+125
+00:09:22,580 --> 00:09:27,400
+the upper limb bones. Articulated proximally with
+
+126
+00:09:27,400 --> 00:09:32,260
+the glenoid fossa، زي ما إحنا شايفين هنا، وتحت مع الـ
+
+127
+00:09:32,260 --> 00:09:35,900
+ulna and radius.
+
+128
+00:09:38,660 --> 00:09:47,660
+مكوناتها هي الـ head والـ diaphysis والـ
+
+129
+00:09:47,660 --> 00:09:52,620
+epiphysis.
+
+130
+00:09:54,320 --> 00:09:57,940
+يعني بنحب إنه نوضح، أنا على الرسم هيكون أوضح وأقرب
+
+131
+00:09:57,940 --> 00:10:01,120
+لكم. إحنا نتكلم عن الـ tuberosities، عن الـ groove،
+
+132
+00:10:01,120 --> 00:10:07,800
+عن الـ bicipital tuberosity، نتكلم عن الـ capitulum.
+
+133
+00:10:07,800 --> 00:10:14,180
+خلينا نوضحها على الـ PowerPoint، ممكن تكون أوضح شوية.
+
+134
+00:10:14,180 --> 00:10:17,920
+يبقى بتتكون من الـ head، greater tuberosity، lesser
+
+135
+00:10:17,920 --> 00:10:21,320
+tuberosity، في عندنا anatomical neck، وفي عندنا
+
+136
+00:10:21,320 --> 00:10:26,040
+surgical neck، و deltoid tuberosity، والـ capitulum، والـ
+
+137
+00:10:26,040 --> 00:10:29,840
+trochlea، و coranoid fossa، و olecranon fossa.
+
+138
+00:10:29,840 --> 00:10:36,260
+هنشوفها على الرسومات. أما الـ radius فهي عبارة عن
+
+139
+00:10:36,260 --> 00:10:42,690
+a long bone، موجودة على الـ thumb side. إيش الـ thumb
+
+140
+00:10:42,690 --> 00:10:46,850
+side؟ اللي هو هذا الـ side. قلنا هنا هنلاقي الـ radius
+
+141
+00:10:46,850 --> 00:10:52,230
+موجودة ناحية الـ thumb، أما الـ ulna موجودة على الـ
+
+142
+00:10:52,230 --> 00:10:55,350
+medial part، فهي الـ most lateral bone.
+
+143
+00:10:57,600 --> 00:11:01,560
+الـ radius، طبعا في الـ articulation with the
+
+144
+00:11:01,560 --> 00:11:06,360
+capitulum of humerus، وفي انخفاض اسمها radial notch
+
+145
+00:11:06,360 --> 00:11:10,800
+of ulna، هي موجودة بهذه... على جنب الـ ulna، بتعطيني
+
+146
+00:11:10,800 --> 00:11:17,240
+articulation with the head of radius، وتتّصل مع الـ
+
+147
+00:11:17,240 --> 00:11:20,980
+scaphoid والـ lunate اللي هما من العظام الـ carpal
+
+148
+00:11:20,980 --> 00:11:25,260
+bones في الـ first row، الـ scaphoid and lunate.
+
+149
+00:11:28,060 --> 00:11:34,900
+طبعا الـ radius، فيها... هي الـ lateral forearm bone اللي
+
+150
+00:11:34,900 --> 00:11:39,740
+ها head، و radial tuberosity، و styloid process. إيش هو
+
+151
+00:11:39,740 --> 00:11:43,100
+الـ styloid process؟ إحنا لو كنا حطينا إيدنا هنا على
+
+152
+00:11:43,100 --> 00:11:46,960
+منطقة الرسغ، بنلاقي إن في عندنا عظمة، إيش العظمة هذه؟
+
+153
+00:11:46,960 --> 00:11:49,840
+حتى لو بنعمل دوران، بتتحرك معانا، هي بنسميها
+
+154
+00:11:49,840 --> 00:11:52,600
+الـ styloid process، اللي هو هذا الـ process اللي
+
+155
+00:11:52,600 --> 00:11:57,360
+إحنا شايفينه هنا على الـ skeleton.
+
+156
+00:12:00,900 --> 00:12:04,880
+أما الـ ulna قلنا فهي أيضا long bone، موجودة في ناحية
+
+157
+00:12:04,880 --> 00:12:10,080
+الـ little finger، في هذا الاتجاه يعني، إحنا بنسميها
+
+158
+00:12:10,080 --> 00:12:13,740
+medial bone of the forearm، articulated
+
+159
+00:12:13,740 --> 00:12:16,720
+proximally with the humerus and radius، and
+
+160
+00:12:16,720 --> 00:12:19,860
+distally with the fibrocartilaginous disc اللي هو
+
+161
+00:12:19,860 --> 00:12:26,670
+موجود في الـ wrist joint في هذه المنطقة. طبعا في
+
+162
+00:12:26,670 --> 00:12:29,350
+الـ trochlear notch، والأوليكرانون process اللي
+
+163
+00:12:29,350 --> 00:12:32,630
+هو هذا. إحنا كلنا لو حطينا إيدنا هنا على مؤخر إيدنا
+
+164
+00:12:32,630 --> 00:12:37,990
+بنحس إن في عندنا عظمة، العظمة هذه عظمة النهاية أو
+
+165
+00:12:37,990 --> 00:12:41,970
+الـ epiphysis of the ulna، بتسمى الأوليكرانون
+
+166
+00:12:41,970 --> 00:12:49,650
+اللي هي موجودة هنا. هذه هي الأوليكرانون. طبعا في عندنا
+
+167
+00:12:49,650 --> 00:12:55,130
+trochlea عشان تعمل attachment مع الـ humerus، وفي عندنا
+
+168
+00:12:55,130 --> 00:13:00,630
+الـ radial notch، قلنا، الموجودة على الجانب، وكذلك
+
+169
+00:13:00,630 --> 00:13:04,470
+في عندنا الـ coranoid process، وفي عندها في نهاية
+
+170
+00:13:04,470 --> 00:13:09,190
+العظمة، في عندنا الـ styloid process اللي هو هنا بهذا
+
+171
+00:13:09,190 --> 00:13:13,490
+الشكل. لو حطينا برضه إيدنا هنا، هنشعر... نشعر أنه في
+
+172
+00:13:13,490 --> 00:13:20,850
+بروز هنا، أو في عظمة بارزة. أما الـ wrist and hand، فإن
+
+173
+00:13:20,850 --> 00:13:23,970
+الـ carpal bones، في 16 carpal bone، ثمانية على
+
+174
+00:13:23,970 --> 00:13:27,710
+
+223
+00:17:45,010 --> 00:17:47,970
+طبعا احنا زي ما رينا على الـ slide كله بنكون شرحنا
+
+224
+00:17:47,970 --> 00:17:52,810
+على الـ skeleton في عندنا الـ pubic arch في عندنا الـ
+
+225
+00:17:52,810 --> 00:17:56,370
+skeletoparasite اللي بالأسكم الـ skeletoparasite
+
+226
+00:17:56,370 --> 00:18:05,890
+اللي هي العظمة اللي احنا بنقعد عليها عادة الـ pubic
+
+227
+00:18:05,890 --> 00:18:09,850
+arch اللي ابتدت الفرامين الفرامين اللي موجود هنا
+
+228
+00:18:09,850 --> 00:18:14,640
+حد بيعمل passage للـ nerve supplies للـ nerve and
+
+229
+00:18:14,640 --> 00:18:16,380
+vascular supplies
+
+230
+00:18:20,400 --> 00:18:24,160
+يعني حاجة اسمها greater and lesser pelvic الـ
+
+231
+00:18:24,160 --> 00:18:27,280
+greater pelvic بتكون من الـ lumber vertebra
+
+232
+00:18:27,280 --> 00:18:31,320
+posteriorly and iliac bone laterally and abdominal
+
+233
+00:18:31,320 --> 00:18:35,020
+wall anteriorly اللي هو هذا الـ greater اللي هو في
+
+234
+00:18:35,020 --> 00:18:40,600
+كل الفروع بتكون موجودة أما الـ lesser فهو عبارة عن
+
+235
+00:18:40,600 --> 00:18:45,380
+الـ sacrum و الـ coccyx من الخلف من هنا الـ lower
+
+236
+00:18:45,380 --> 00:18:49,880
+ilium و الـ ischium و الـ pubis laterally
+
+237
+00:18:53,140 --> 00:18:57,820
+طبعا في فرق بين الـ male and female pelvic، الفرق
+
+238
+00:18:57,820 --> 00:19:03,560
+بينهم هذا خلق لإنه الـ female pelvic خلق عشان يكون
+
+239
+00:19:03,560 --> 00:19:07,580
+في passage للجنين
+
+240
+00:19:07,580 --> 00:19:12,380
+أثناء الـ delivery فهذا بيكون فيه خصائص مختلفة شوية
+
+241
+00:19:12,380 --> 00:19:19,060
+عن الـ male pelvic، الـ female pelvic يكون more
+
+242
+00:19:19,060 --> 00:19:23,540
+flared border hip pubic arch angle greater حتى
+
+243
+00:19:23,540 --> 00:19:27,140
+تسمح passage للـ baby more distance between
+
+244
+00:19:27,140 --> 00:19:32,060
+ischial spine and ischial tuberosity وفي عندنا الـ
+
+245
+00:19:32,060 --> 00:19:37,100
+sacral curvature shorter and flatter و العظام
+
+246
+00:19:37,100 --> 00:19:43,470
+طبعا أخف، طبعا هذا درس توضيحي بين الفرق ما
+
+247
+00:19:43,470 --> 00:19:45,370
+بين الـ male and female
+
+248
+00:19:48,300 --> 00:19:51,920
+بالفعل طبعا عظام الـ lower limbs زي ما احنا حكينا
+
+249
+00:19:51,920 --> 00:19:54,660
+الـ femur, patella, tibia, fibula, tarsal,
+
+250
+00:19:54,780 --> 00:19:59,440
+metatarsal and phalanges، الـ femur هي longest bone زي
+
+251
+00:19:59,440 --> 00:20:04,280
+ما احنا شايفينها، الـ largest bone كمان فيها الـ fovea
+
+252
+00:20:04,280 --> 00:20:08,420
+capitis، هي في عندها فتحة هنا جوة الـ head في
+
+253
+00:20:08,420 --> 00:20:11,540
+المنطقة موجودة بتعمل attachments لإيليوفيمرال
+
+254
+00:20:11,540 --> 00:20:15,020
+ligament فيها الـ greater trochanter فيها الـ head طبعا
+
+255
+00:20:15,020 --> 00:20:20,850
+فيها الـ neck فيها الـ greater trochanter, lesser trochanter و في
+
+256
+00:20:20,850 --> 00:20:24,870
+عندنا الـ linea aspera اللي بيعمل attachment هي
+
+257
+00:20:24,870 --> 00:20:30,690
+شايفينه هنا احنا، كده بيعطينا attachment للـ
+
+258
+00:20:30,690 --> 00:20:36,450
+quadriceps muscles و فيها الـ condyles و الـ epicondyles
+
+259
+00:20:36,450 --> 00:20:40,070
+اللي هي قلنا epicondyles، في عندنا على
+
+260
+00:20:40,070 --> 00:20:43,450
+طرفين الـ condyles في عندنا بروز صغير بنسميه epicondyles
+
+261
+00:20:43,450 --> 00:20:47,540
+أما البتلة فهي الـ kneecap نسميها الـ
+
+262
+00:20:47,540 --> 00:20:50,380
+anterior surface of the knee، عظمة من نوع
+
+263
+00:20:50,380 --> 00:20:55,980
+sesamoid bone بتكون محاطة بأوتار الـ quadriceps
+
+264
+00:20:55,980 --> 00:21:02,740
+التيبيا بتكون من الشافت أو الـ shaft، الـ shaft في لها
+
+265
+00:21:02,740 --> 00:21:08,220
+بروز كده طبعا هي الـ medial condyle، العظمة اللي فيها
+
+266
+00:21:08,220 --> 00:21:10,880
+condyles و tibial tuberosity عشان الـ tibial
+
+267
+00:21:10,880 --> 00:21:14,760
+tuberosity موجودة هنا عشان تعمل attachment للـ
+
+268
+00:21:14,760 --> 00:21:19,440
+quadriceps tendon أو الـ patellar tendon و في عندها
+
+269
+00:21:19,440 --> 00:21:22,060
+لها الـ anterior crest كمان في لها medial
+
+270
+00:21:22,060 --> 00:21:25,720
+malleolus اللي هي احنا كلنا لو حسينا
+
+271
+00:21:28,890 --> 00:21:32,370
+فبنلاقي هنا فيه بروز، هذا البروز اسمه الـ medial
+
+272
+00:21:32,370 --> 00:21:35,250
+malleolus وفي كمان بروز للفيبيولا اسمه الـ
+
+273
+00:21:35,250 --> 00:21:39,970
+lateral malleolus أما الفيبيولا فهي عظمة
+
+274
+00:21:39,970 --> 00:21:42,890
+lateral و long cylindrical head، هذه non
+
+275
+00:21:42,890 --> 00:21:46,430
+-weight bearing bone ما بتحملش أي weight bearing
+
+276
+00:21:46,430 --> 00:21:50,430
+عشان هي لو انكسرت ما بتأثر كتير على المشي إلا من
+
+277
+00:21:50,430 --> 00:21:56,000
+خلال الـ ankle و foot، طبعا الـ ankle and foot في
+
+278
+00:21:56,000 --> 00:22:01,380
+عندنا عدد من العظام تقريبا في عندنا أربعة عشر عظمة
+
+279
+00:22:01,380 --> 00:22:04,920
+هي الـ calcaneus و الـ talus و الـ navicular و
+
+280
+00:22:04,920 --> 00:22:08,080
+الـ cuboid و الـ cuneiform و عندنا الـ lateral cuneiform
+
+281
+00:22:08,080 --> 00:22:11,240
+و الـ intermediate cuneiform و الـ medial cuneiform
+
+282
+00:22:11,240 --> 00:22:15,220
+كلهم هدول بيكونوا موضحين على الـ skeleton بهذا
+
+283
+00:22:15,220 --> 00:22:21,370
+الشكل زي ما احنا شايفين، طبعا الـ metatarsals في
+
+284
+00:22:21,370 --> 00:22:25,210
+عندنا ten metatarsals، خمسة على اليمين و خمسة
+
+285
+00:22:25,210 --> 00:22:30,010
+على اليسار، و في عندنا الـ phalanges زي ما قلنا في
+
+286
+00:22:30,010 --> 00:22:38,430
+عندنا الـ four lateral toes فيهم ثلاث phalanges اللي هي
+
+287
+00:22:38,430 --> 00:22:42,050
+الـ proximal, intermediate and distal، أما الـ thumb
+
+288
+00:22:42,050 --> 00:22:48,150
+فهو only two phalanges، بالظبط نفس تركيبة الـ upper
+
+289
+00:22:48,150 --> 00:22:48,410
+hand
+
+290
+00:22:51,900 --> 00:22:55,040
+طبعا في حاجة اسمها arches of the foot، لو لاحظنا
+
+291
+00:22:55,040 --> 00:22:58,480
+إن احنا كلنا لما بنمشي على أسفل القدم عندنا فبنلاقي فيه
+
+292
+00:22:58,480 --> 00:23:02,840
+arch، في عندنا medial arch موجود على الناحية اليمين
+
+293
+00:23:02,840 --> 00:23:05,360
+هو أنا الـ skeleton اللي عندي هنا مشوه شوية بس أنا
+
+294
+00:23:05,360 --> 00:23:09,320
+بقدر أوضح هنا إن فيه هنا الـ medial arch وفي هنا
+
+295
+00:23:09,320 --> 00:23:13,400
+slightly smaller lateral arch، ما اعرفش
+
+296
+00:23:13,400 --> 00:23:18,310
+إذا واضح بالصورة أو لأ، وفي عندنا كمان transverse
+
+297
+00:23:18,310 --> 00:23:22,050
+arch، هدول إيش وظيفتهم؟ الـ arches هدول بيعملوا عملية
+
+298
+00:23:22,050 --> 00:23:25,930
+shock absorption عشان عظام الرجل مش كلها بتنطبق
+
+299
+00:23:25,930 --> 00:23:29,330
+على الأرض، يكون فيه تاخد ضربة، هذه بتعمل shock
+
+300
+00:23:29,330 --> 00:23:35,630
+absorption يعني بتخفف الصدمات على عظام الـ foot
+
+301
+00:23:35,630 --> 00:23:38,430
+طبعا في ناس عندهم flat foot، عندنا هنقول من إيش
+
+302
+00:23:38,430 --> 00:23:42,640
+هدول ممكن يعني، طبعا الـ sole of the foot does not
+
+303
+00:23:42,640 --> 00:23:47,100
+rest flat on the ground، في عندنا .. ليش؟ ليش
+
+304
+00:23:47,100 --> 00:23:49,880
+بيكونش flat؟ بيكون في عندنا arches بتsupport the weight
+
+305
+00:23:49,880 --> 00:23:53,540
+of the body، طبعا بيكون في عندنا blood vessels
+
+306
+00:23:53,540 --> 00:23:57,000
+موجودة في الـ sole of the foot، لو كانت الأرجل بتنزل
+
+307
+00:23:57,000 --> 00:24:01,540
+flat على الأرض فبيصير في عندنا squeezing أو ضغط على
+
+308
+00:24:01,540 --> 00:24:05,200
+الـ vessels هذه، فهذه ممكن إنها تقلل الدورة الدموية
+
+309
+00:24:05,200 --> 00:24:08,480
+عشان هيك بتكون مقوسة عشان لما احنا ننزل رجلنا على
+
+310
+00:24:08,480 --> 00:24:13,690
+الأرض ما تنزلش flat تضغط الأوعية الدموية
+
+311
+00:24:18,340 --> 00:24:22,660
+طبعا على الـ powerpoint موضحة الـ arches، في عندنا
+
+312
+00:24:22,660 --> 00:24:26,520
+بعض المشاكل اللي بتصيب الـ lower limb أو الـ foot
+
+313
+00:24:26,520 --> 00:24:30,400
+بالذات في حاجة اسمها hallux valgus، تلاحظ إن بعض
+
+314
+00:24:30,400 --> 00:24:37,480
+الناس ممكن يصير فيه خلل في تركيبة الـ first toe
+
+315
+00:24:37,480 --> 00:24:42,560
+اللي هو الـ hallux احنا بنسميه، بيصير فيه deviation of
+
+316
+00:24:42,560 --> 00:24:45,780
+the great toe at the metatarsophalangeal joint
+
+317
+00:24:45,780 --> 00:24:50,720
+طبعا الـ incidence أكتر في الـ women من الـ men، بينتج
+
+318
+00:24:50,720 --> 00:24:53,480
+عن الـ bad fitting shoes، طبعا في الـ shoes أنتم
+
+319
+00:24:53,480 --> 00:24:56,400
+عارفينها اللي هي الـ .. الـ .. الـ .. الـ حذاء الضيق
+
+320
+00:24:56,400 --> 00:25:01,120
+هذه فبتلاقي الأصابع بتكون كده يعني مضغوطة جواها
+
+321
+00:25:01,120 --> 00:25:05,350
+فعلى الـ long term ممكن تعمل لنا مشاكل، أو ممكن يكون في
+
+322
+00:25:05,350 --> 00:25:10,770
+عندنا short للـ first metatarsal بتؤدي لهذه المشكلة
+
+323
+00:25:10,770 --> 00:25:13,850
+طبعا إذا صارت الـ deformity هذه موجودة فمعناها هي
+
+324
+00:25:13,850 --> 00:25:18,530
+إنها ممكن إنها تتطور نتيجة pull of the
+
+325
+00:25:18,530 --> 00:25:23,180
+muscles around the hallux، طبعا في الـ hallux rigidus
+
+326
+00:25:23,180 --> 00:25:26,280
+ممكن يصير فيه calcification على الـ
+
+327
+00:25:26,280 --> 00:25:29,220
+metatarsophalangeal joints أو osteoarthritis
+
+328
+00:25:29,220 --> 00:25:35,580
+changes فممكن هذه تعمل painful and stiff toe،
+
+329
+00:25:35,580 --> 00:25:39,610
+big toe، في الـ pes planus الناس اللي بنسميهم الـ flat
+
+330
+00:25:39,610 --> 00:25:44,010
+feet هدول أرجلهم بتكون الـ arches كلها ممسوحة
+
+331
+00:25:44,010 --> 00:25:49,550
+فبتنزل رجلهم على الأرض مباشرة، هذا عبارة عن
+
+332
+00:25:49,550 --> 00:25:53,350
+depression أو collapse للـ longitudinal arch،
+
+333
+00:25:53,350 --> 00:25:58,310
+result  إن foot كلها بتكون laterally بتروح على
+
+334
+00:25:58,310 --> 00:26:03,190
+الناحية الـ laterally، الـ head of the talus no
+
+335
+00:26:03,190 --> 00:26:07,190
+longer supported، the cause of a flat foot both
+
+336
+00:26:07,190 --> 00:26:11,110
+congenital or acquired، congenital إنه بنولد لأنه
+
+337
+00:26:11,110 --> 00:26:14,730
+من عائلة عندهم flat foot أو acquired لأنه في عندنا
+
+338
+00:26:14,940 --> 00:26:19,180
+الـ .. العوامل الـ .. الـ .. الشذوذ اللي بتستخدم دائما
+
+339
+00:26:19,180 --> 00:26:23,180
+ممكن تكون منذ الطفولة سيئة فبتأثر هذا، وأعطيكم
+
+340
+00:26:23,180 --> 00:26:25,800
+العافية وأرجو أن أكون أوضحت في مجال الـ
+
+341
+00:26:25,800 --> 00:26:28,900
+appendicular system والمشاكل اللي ممكن تصيب الـ foot
+
+342
+00:26:28,900 --> 00:26:30,380
+السلام عليكم ورحمة الله
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..8b027f539e1c810a8bfb8a55d98be72e1fa9e48b
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4_postprocess.srt
@@ -0,0 +1,1368 @@
+1
+00:00:04,930 --> 00:00:07,310
+باسم الله الرحمن الرحيم والصلاة والسلام علي سيدنا
+
+2
+00:00:07,310 --> 00:00:11,430
+محمد سيد المرسلين وعلى الله هو صح بيه أجمعين طبعا
+
+3
+00:00:11,430 --> 00:00:17,070
+اليوم هنستكمل في مساق التشريح في ال skeletal
+
+4
+00:00:17,070 --> 00:00:19,790
+system الجزء التالت هنتكلم عن ال appendicular
+
+5
+00:00:19,790 --> 00:00:23,010
+system و اليوم انا اخترت ان يكون معنا ال skeleton
+
+6
+00:00:23,010 --> 00:00:26,850
+عشان نراجع ال axial skeleton وبالتالي ننزل لل
+
+7
+00:00:26,850 --> 00:00:32,790
+appendicular skeletonالحقيقة احنا حكينا انه ال
+
+8
+00:00:32,790 --> 00:00:36,450
+axle skeleton بتكون من ال head و ال neck و ال
+
+9
+00:00:36,450 --> 00:00:41,490
+vertebral column و ال ..ال rib cage يعني او ال
+
+10
+00:00:41,490 --> 00:00:45,530
+trunk هنا احنا بنسميه ال trunk وقلنا انه موجود على
+
+11
+00:00:45,530 --> 00:00:50,630
+ال axial skeleton موجود عندنا ال pectoral girdle و
+
+12
+00:00:50,630 --> 00:00:54,030
+عندنا ال pelvic girdle اللي بيكونوا مكون أساسي
+
+13
+00:00:54,030 --> 00:00:57,630
+لمحاضرتنا اليوم اللي هي ال abdicular system اللي
+
+14
+00:00:57,630 --> 00:01:01,210
+هو بتتكون من ال upper limb و lower limb مع ال
+
+15
+00:01:01,210 --> 00:01:05,580
+pectoral girdle و pelvic girdleطبعا إحنا شايفين
+
+16
+00:01:05,580 --> 00:01:09,040
+إنه قدامنا زي ما إحنا شايفين في ال skeleton لو
+
+17
+00:01:09,040 --> 00:01:14,080
+أجينا أخدنا هذا ال ال lateral view فبنلاقي إنه في
+
+18
+00:01:14,080 --> 00:01:18,720
+عندنا ال neck ال head و في عندنا lordosis ناحية ال
+
+19
+00:01:18,720 --> 00:01:23,080
+cervical column و عندنا kyphosis ناحية إذا نرجع
+
+20
+00:01:23,080 --> 00:01:25,980
+شوية المحاضرة اللي فاتت kyphosis من ناحية ال
+
+21
+00:01:25,980 --> 00:01:30,960
+thoracicوفى عندنا ال lordosis على ال lumber وفى
+
+22
+00:01:30,960 --> 00:01:37,420
+عندنا ال sacrum and coccyx وطبعا على ال rib cage
+
+23
+00:01:37,420 --> 00:01:41,800
+موجود عندنا ال scapula and clavicle اللى بترتبط
+
+24
+00:01:41,800 --> 00:01:45,500
+فيهم ال upper limb و كذلك عندنا ال pelvic bone
+
+25
+00:01:45,500 --> 00:01:51,490
+اللى بتعطينى ارتباط مع ال lower extremityهذا
+
+26
+00:01:51,490 --> 00:01:55,470
+بالنسبة للـ axial skeleton لو جينا لمكونات ال
+
+27
+00:01:55,470 --> 00:01:59,850
+appendicular skeleton فبناخد في ال upper part هذا
+
+28
+00:01:59,850 --> 00:02:03,170
+بنسمي احنا ال non-weight peering part في عنا ال
+
+29
+00:02:03,170 --> 00:02:07,750
+scapula anticlepical مكون للpectoral girdle and ال
+
+30
+00:02:07,750 --> 00:02:10,990
+upper limb أنا هشرح اليوم بسرعة عشان احنا نرجع لل
+
+31
+00:02:10,990 --> 00:02:15,530
+slide اللي معنا في عنا ال upper limb فيها عدد من
+
+32
+00:02:15,530 --> 00:02:23,620
+العضام تتكون منعدم ال humorous في عندنا ال radius
+
+33
+00:02:23,620 --> 00:02:27,780
+العضمة المتحركة اللى بتعمل دوران وفي عندنا الانا
+
+34
+00:02:27,780 --> 00:02:32,640
+بتعمل articulation مع ال wrists في عندنا ال eight
+
+35
+00:02:32,640 --> 00:02:37,060
+carpal bonesفي عندنا first row أربع second row
+
+36
+00:02:37,060 --> 00:02:44,160
+أربع في عندنا الميتا carpals وعندنا الفلانجيز طبعا
+
+37
+00:02:44,160 --> 00:02:47,060
+احنا بنعرف أنه في عندنا عدد الفلانجيز في الأربع
+
+38
+00:02:47,060 --> 00:02:51,980
+fingersموجود في ال thumb في عندنا two phalanges
+
+39
+00:02:51,980 --> 00:02:55,960
+وفي الأربع أصابع التانين في عندنا three phalanges
+
+40
+00:02:55,960 --> 00:02:59,980
+نفس التركيب هذا ونفس عدم تقريبا يعني عدد مقارب من
+
+41
+00:02:59,980 --> 00:03:04,080
+العظام موجود في عندنا مشابه له في ال lower limb بس
+
+42
+00:03:04,080 --> 00:03:08,680
+هنا ال lower limb العظام طبعتها أطول شوية يعني
+
+43
+00:03:08,680 --> 00:03:13,260
+قوتها أكبر ليش؟ لأنها weight bearing bones المعنى
+
+44
+00:03:13,260 --> 00:03:16,840
+أنه إحنا لما بنوقف نوقف على أقدام ال lower limb
+
+45
+00:03:18,030 --> 00:03:24,770
+البلفك هو موجود عبارة عن عضام الاليوم والاسكيان مع
+
+46
+00:03:24,770 --> 00:03:29,930
+البيوبيس بلتحموا مع الساكرام في الخلف هنا بيكونوا
+
+47
+00:03:29,930 --> 00:03:34,170
+خلينا نقول حواضتكون في الـ anterior part في ال
+
+48
+00:03:34,170 --> 00:03:37,070
+upper pelvic موجود في عيننا ال abdominal viscerals
+
+49
+00:03:37,070 --> 00:03:40,210
+وفي ال lower part في عيننا ال genitalia وكمان
+
+50
+00:03:40,210 --> 00:03:44,010
+بيصير في عيننا attachment لإن الوزن بنزل من الرأس
+
+51
+00:03:44,010 --> 00:03:47,950
+لل cervical وبروح على ال trunk و بيجي على ال
+
+52
+00:03:47,950 --> 00:03:52,370
+lumbar و بيصير له توزيع على ال both pelvic bone
+
+53
+00:03:52,370 --> 00:03:56,230
+تمام؟ و بعدها بينزل على ال lower limbs و احنا ال
+
+54
+00:03:56,230 --> 00:04:00,290
+contact مع الأرض بيكون عيننا ال foot طبعا في عيننا
+
+55
+00:04:00,290 --> 00:04:04,570
+ال longestو ال biggest bone in the body زي ال ..
+
+56
+00:04:04,570 --> 00:04:08,810
+اللي هي الفيمر و في إنه كذلك بنحاول إنه .. ان ..
+
+57
+00:04:08,810 --> 00:04:13,570
+ان .. انحط قدامنا ال lower limbفي عندنا في ال
+
+58
+00:04:13,570 --> 00:04:16,390
+anterior part of the knee في عندنا sesamoid bone
+
+59
+00:04:16,390 --> 00:04:19,370
+اللى تسمى ال patella في ال anterior part of the
+
+60
+00:04:19,370 --> 00:04:23,050
+knee وفي عندنا ال tibia و ال tibia هادى هنشرح
+
+61
+00:04:23,050 --> 00:04:27,510
+مكوناتها على الصورة ال tibia و ال fibula احنا
+
+62
+00:04:27,510 --> 00:04:29,970
+قولنا هنا في قلنا في radius لكن في عندنا في lower
+
+63
+00:04:29,970 --> 00:04:32,980
+limb في عندنا ال tibia و ال fibulaالتيبيا هي ال
+
+64
+00:04:32,980 --> 00:04:35,600
+wet bearing bone اما الفيبولا it is a non wet
+
+65
+00:04:35,600 --> 00:04:38,980
+bearing bone بتلتحم هدولة عن طريق ال ankle joint
+
+66
+00:04:38,980 --> 00:04:43,080
+مع ال talus مع ال carpa ال tarsal هلقيتها باختلف
+
+67
+00:04:43,080 --> 00:04:46,520
+اللفظ بنقول عنها tarsal bone في عندنا اللي هي ال
+
+68
+00:04:46,520 --> 00:04:50,540
+bone اللي ال calcaneus و ال talus و في عندنا ال
+
+69
+00:04:50,540 --> 00:04:53,300
+metatarsals
+
+70
+00:04:53,940 --> 00:04:58,140
+وفي عندنا الفلانجيز وهذه برضه نفس تقسيمات ال upper
+
+71
+00:04:58,140 --> 00:05:02,760
+limb هنتعرف عليهم واحدة واحدة من خلال محاضرتنا
+
+72
+00:05:02,760 --> 00:05:09,930
+لليوم، طيب نشوف إيش؟في عيننا على ال slides اليوم
+
+73
+00:05:09,930 --> 00:05:15,590
+هنتكلم عن ال appendicular system اللى هو فى ال
+
+74
+00:05:15,590 --> 00:05:18,570
+upper part of the body ال pictorial girdle
+
+75
+00:05:18,570 --> 00:05:22,150
+attached to the upper limb to the trunk و البلف
+
+76
+00:05:22,150 --> 00:05:25,990
+الجردل زى ما وضحنا attached lower limbupper and
+
+77
+00:05:25,990 --> 00:05:29,110
+lower limbs differs in function لكن هم بيختلفوا في
+
+78
+00:05:29,110 --> 00:05:33,430
+الوظيفة قلنا الإيد عشان احنا نقدر نتناول الأشياء و
+
+79
+00:05:33,430 --> 00:05:37,590
+نتحرك و ناكل و نشرب و نمشط و نلبس أما الرجل ال two
+
+80
+00:05:37,590 --> 00:05:42,650
+lower limbs فهم بي .. مسئولين عن عملية ال
+
+81
+00:05:42,650 --> 00:05:44,650
+ambulation و المشي
+
+82
+00:05:46,890 --> 00:05:50,590
+الـ articulation of the pictorial girdle زي ما
+
+83
+00:05:50,590 --> 00:05:55,190
+احنا شايفين في عندنا ال clavicle هنا و في عندنا ال
+
+84
+00:05:55,190 --> 00:06:00,130
+scapula ال clavicle مع ال scapula في عندنا joint
+
+85
+00:06:00,130 --> 00:06:06,540
+اسمهأكروميو clavicular joint ومع الستيرنم هنا اللي
+
+86
+00:06:06,540 --> 00:06:11,720
+هي عضمة القص فيه sternoclavicular joint تمام؟ وفي
+
+87
+00:06:11,720 --> 00:06:15,380
+عندنا هنا في نهاية في ال lateral part في عندنا
+
+88
+00:06:15,380 --> 00:06:19,480
+حاجة أسمها ال glenoid cavity بتصير تعمل
+
+89
+00:06:19,480 --> 00:06:23,320
+articulation مع ال head of the humerus
+
+90
+00:06:27,990 --> 00:06:32,030
+طبعا زي ما وضحنا ال upper extremity consists of
+
+91
+00:06:32,030 --> 00:06:35,330
+bones of the shoulder girdle, upper arm, lower
+
+92
+00:06:35,330 --> 00:06:39,530
+arm, breast and ham, shoulder girdle made up of
+
+93
+00:06:39,530 --> 00:06:43,110
+scapula and clavicle زي ما احنا وضحنا هنا ال
+
+94
+00:06:43,110 --> 00:06:49,630
+clavicle form only bonya joint with the trunk أما
+
+95
+00:06:49,630 --> 00:06:53,990
+الsterno نسمي الsterno clavicular joint لكن ال ..
+
+96
+00:06:53,990 --> 00:06:57,030
+ال scapula مافيش joint مع ال trunk ال scapula
+
+97
+00:06:57,030 --> 00:07:01,250
+محطوطة حط يعني زي شنكل كده عاملة ال scapula مع ال
+
+98
+00:07:01,250 --> 00:07:06,690
+clavicle و محطوطين كده زي القلقة على ال trunk فال
+
+99
+00:07:06,690 --> 00:07:11,070
+scapula حقيقي فش joint ال joint الوحيد اللي موجود
+
+100
+00:07:11,070 --> 00:07:17,430
+فيها هنا مع ال .. ال ..الـ acromioclavicular joint
+
+101
+00:07:17,430 --> 00:07:21,370
+وهذا الـ joint أصلا مع ال upper limb بعيد عن ال
+
+102
+00:07:21,370 --> 00:07:26,410
+trunk الـ
+
+103
+00:07:26,410 --> 00:07:30,730
+pectoral girdle
+
+104
+00:07:30,730 --> 00:07:34,110
+اللي هو مكوناته الأساسية لـ clavicle أو ال scapula
+
+105
+00:07:34,110 --> 00:07:38,790
+وهو طبيعته بيعمل support على ال upper limb
+
+106
+00:07:44,990 --> 00:07:50,250
+هذه شرحناها نروح لل power point اللي عندنا نوضح
+
+107
+00:07:50,250 --> 00:07:56,210
+على زي ما هو مضح على الرسم نقلب ناخد صورة خلفية
+
+108
+00:07:56,210 --> 00:08:00,170
+لأن ال scapula مافيش إمكانية إلا ننظر إليها إلا من
+
+109
+00:08:00,170 --> 00:08:04,250
+القلب فهنا بنلاحظ أن ال scapula ليش مكوناتها فيها
+
+110
+00:08:04,250 --> 00:08:08,250
+spine بينتهي بالacromion ال process هذا و فيها
+
+111
+00:08:08,250 --> 00:08:13,250
+inferiorInfraspinous fossa وفيها Supraspinous
+
+112
+00:08:13,250 --> 00:08:17,450
+fossa هنا وهذه بتعطي attachment للعضلات هنا ال
+
+113
+00:08:17,450 --> 00:08:21,150
+medial border وفي هنا ال apex وفي هنا ال lateral
+
+114
+00:08:21,150 --> 00:08:26,850
+border of the scapula اللي بيروح بيوصل ل .. بيعمل
+
+115
+00:08:26,850 --> 00:08:29,750
+اللي بيكونني في ال lateral part اللي هي ال glenoid
+
+116
+00:08:29,750 --> 00:08:36,530
+كافة اللي بتعمل attachment مع ال .. الhemerasفي
+
+117
+00:08:36,530 --> 00:08:40,350
+حاجة اسمها coracoid process زي احنا شايفينه بهذا
+
+118
+00:08:40,350 --> 00:08:45,050
+المظهر هنا وهذا وظيفته برضه بيعملي muscular
+
+119
+00:08:45,050 --> 00:08:53,950
+attachment أما
+
+120
+00:08:53,950 --> 00:09:00,230
+ال .. ال arm and forearm and the hand بتكونوا
+
+121
+00:09:00,230 --> 00:09:07,940
+تقريبا من thirty bones تلاتين عضمةزي ما احنا وضحنا
+
+122
+00:09:07,940 --> 00:09:11,440
+قبل هيك Humerus Radius and Ulnar and Carpal Bone
+
+123
+00:09:11,440 --> 00:09:17,200
+and Metacarpal and Phalanges تم الـHumerus من
+
+124
+00:09:17,200 --> 00:09:22,580
+صفاتها إنها long bone وهي تقريباً the longest of
+
+125
+00:09:22,580 --> 00:09:27,400
+the upper limb bone Articulated approximately with
+
+126
+00:09:27,400 --> 00:09:32,260
+the Granoid Fossa زي ما احنا شايفين هنا وتحت مع ال
+
+127
+00:09:32,260 --> 00:09:35,900
+Ulna and Radius
+
+128
+00:09:38,660 --> 00:09:47,660
+المكونات هي الـ head و الـ diaphysis و الـ
+
+129
+00:09:47,660 --> 00:09:52,620
+epiphysis
+
+130
+00:09:54,320 --> 00:09:57,940
+يعني بنحب أنه نوضح أنا على الرسم هيكون أوضح و أقرب
+
+131
+00:09:57,940 --> 00:10:01,120
+لإلكوا نحنا نتكلم عن ال tuberosities عن ال groove
+
+132
+00:10:01,120 --> 00:10:07,800
+عن ال bicepital tuberosity نتكلم عن الcapitulum
+
+133
+00:10:07,800 --> 00:10:14,180
+خلنا نوضحها على ال powerpoint ممكن تكون أوضح شويه
+
+134
+00:10:14,180 --> 00:10:17,920
+يبقىتتكوّن من الـ head greater tuberosity لزرد
+
+135
+00:10:17,920 --> 00:10:21,320
+تيابرزوتي في عندنا anatomical neck و في عندنا
+
+136
+00:10:21,320 --> 00:10:26,040
+surgical neck و deltoid tuberosity و الcapitulum و
+
+137
+00:10:26,040 --> 00:10:29,840
+التروكليا و الكورونايد فوسة و الكورونايد فوسة
+
+138
+00:10:29,840 --> 00:10:36,260
+هنشوفها على الرسومات أما ال radius فهي عبارة عن
+
+139
+00:10:36,260 --> 00:10:42,690
+ash longبون موجودة على ال thumb side ايش ال thumb
+
+140
+00:10:42,690 --> 00:10:46,850
+side اللي هو هذا ال side قلنا هنا هلاقي ال radius
+
+141
+00:10:46,850 --> 00:10:52,230
+موجودة ناحية ال thumb أما الألنة موجودة على ال
+
+142
+00:10:52,230 --> 00:10:55,350
+medial part فهي ال most lateral bone
+
+143
+00:10:57,600 --> 00:11:01,560
+الradius طبعا في ال articulation with the
+
+144
+00:11:01,560 --> 00:11:06,360
+capitulum of humerus وفي انحجر اسمها radial notch
+
+145
+00:11:06,360 --> 00:11:10,800
+of ulna هي موجودة بهذه على جنب ال ulna بتعطيني
+
+146
+00:11:10,800 --> 00:11:17,240
+articulation with the head of radius و تفتلي مع ال
+
+147
+00:11:17,240 --> 00:11:20,980
+escapode و ال lunate اللي هم من العضام ال carbal
+
+148
+00:11:20,980 --> 00:11:25,260
+bone في ال first row ال escapode and lunate
+
+149
+00:11:28,060 --> 00:11:34,900
+طبعا ال radius فيها هي ال lateral forearm هون اللي
+
+150
+00:11:34,900 --> 00:11:39,740
+ها head و radial capacity وstelloid process ايش هو
+
+151
+00:11:39,740 --> 00:11:43,100
+الstelloid process احنا لو كنا حطينا ايدنا هنا على
+
+152
+00:11:43,100 --> 00:11:46,960
+منطقة الرسخ بنلاقي ان في عندنا عضمة ايش العضمة هذه
+
+153
+00:11:46,960 --> 00:11:49,840
+حتى لو بنعمل دوران تتحرك معانا هي نسميها
+
+154
+00:11:49,840 --> 00:11:52,600
+الstelloid process اللي هو هذا ال process اللي
+
+155
+00:11:52,600 --> 00:11:57,360
+احنا شايفينه هنا على ال skeleton
+
+156
+00:12:00,900 --> 00:12:04,880
+أما اللي قالنا فهي أيضا long bone موجودة في ناحية
+
+157
+00:12:04,880 --> 00:12:10,080
+ال little finger في هذا الاتجاه يعني احنا بسميها
+
+158
+00:12:10,080 --> 00:12:13,740
+medial bone of the forearm articulated
+
+159
+00:12:13,740 --> 00:12:16,720
+approximately with the humerus and radius and
+
+160
+00:12:16,720 --> 00:12:19,860
+distally with the fibrocartilaginal disk اللي هو
+
+161
+00:12:19,860 --> 00:12:26,670
+موجود في ال wrist joint في هذه المنطقة طبعافي
+
+162
+00:12:26,670 --> 00:12:29,350
+الـTrochlear Notch والأوليكرانون ال process اللي
+
+163
+00:12:29,350 --> 00:12:32,630
+هو هذا احنا كلنا لو حطينا ايدنا هنا على أفق ايدنا
+
+164
+00:12:32,630 --> 00:12:37,990
+بنحس ان في عندنا عضمة العضمة هذه عضمة النهاية او
+
+165
+00:12:37,990 --> 00:12:41,970
+ال epiphysis of the humerus بتسمى الأوليكرانون
+
+166
+00:12:41,970 --> 00:12:49,650
+اللي هي موجودة هنا هذه هيالأوليكرانون طبعا في عنا
+
+167
+00:12:49,650 --> 00:12:55,130
+تركليا عشان تعمل attachment مع الlehumeras وفي عنا
+
+168
+00:12:55,130 --> 00:13:00,630
+ال radial notch أفقالنا الموجودة على الجانب وكذلك
+
+169
+00:13:00,630 --> 00:13:04,470
+في عنا الكورينويد ال process وفي إليها في نهاية
+
+170
+00:13:04,470 --> 00:13:09,190
+العطمة في عنا الacylide process اللي هو hand بهذا
+
+171
+00:13:09,190 --> 00:13:13,490
+الشكل لو حطينا برضه إيدنا هنا هنشعر في نشعر أنه في
+
+172
+00:13:13,490 --> 00:13:20,850
+بروز هنا أو في عطمة بارزةأما ال wrist and hand فإن
+
+173
+00:13:20,850 --> 00:13:23,970
+ال carpal bones في 16 carpal bone تمانية على
+
+174
+00:13:23,970 --> 00:13:27,710
+اليمين و تمانية على ال upper limb ال right and
+
+175
+00:13:27,710 --> 00:13:33,190
+left موزعة في two rows هنشوفهم الآن وفي 10 متر
+
+176
+00:13:33,190 --> 00:13:38,210
+carpal و 28 phalanges في عندنا ال proximal
+
+177
+00:13:38,210 --> 00:13:40,730
+phalange وفي عندنا ال intermediate phalange وفي
+
+178
+00:13:40,730 --> 00:13:45,450
+عندنا ال distal phalange زي ما احنا شايفينطبعا ال
+
+179
+00:13:45,450 --> 00:13:49,870
+carpel bones هم مزعين في two rows في عندنا
+
+180
+00:13:49,870 --> 00:13:52,930
+الترابيزويد والترابيزيوم والسكافويد واللونات ال
+
+181
+00:13:52,930 --> 00:13:58,330
+first row وكمان في عندنا ال second row عبارة عن
+
+182
+00:13:58,330 --> 00:14:03,950
+الكبتات والهامات لأ sorry السكافويد واللونات
+
+183
+00:14:03,950 --> 00:14:08,090
+والبيزيفورمس والتركتريام هدو ال first row اما
+
+184
+00:14:08,090 --> 00:14:11,890
+الترابيزويد والترابيزيوم والكبتات والهامات هما ال
+
+185
+00:14:11,890 --> 00:14:13,110
+second row
+
+186
+00:14:15,930 --> 00:14:21,210
+طبعا لو روحنا ل lower extremity فlower extremity
+
+187
+00:14:21,210 --> 00:14:25,970
+قولنا مكون من ال hip bones فى عندنا ال acetabulum
+
+188
+00:14:25,970 --> 00:14:29,170
+articulated with the head of the humerus فى عندنا
+
+189
+00:14:29,170 --> 00:14:32,050
+ال greater retrocanter اللى شايفينه هنا وعندنا ال
+
+190
+00:14:32,050 --> 00:14:35,690
+lesser retrocanter وهى عبارة عن long bone فى عندنا
+
+191
+00:14:35,690 --> 00:14:40,870
+إلها acres وفى عندها lower part عبارة عن two
+
+192
+00:14:40,870 --> 00:14:48,440
+condylesarticulate with the tibia وبتنتهي كمان
+
+193
+00:14:48,440 --> 00:14:55,700
+بنسميها عضمة ال thigh عضمة الفيمر وفي عندنا ال leg
+
+194
+00:14:55,700 --> 00:14:59,640
+اللي بتتكون من ال two bones و ال ankle and foot
+
+195
+00:14:59,640 --> 00:15:06,290
+روح لل بالفك oneطبعا فيه إنا أربعة من الإضام بتكون
+
+196
+00:15:06,290 --> 00:15:11,150
+ال pelvic bone وضفتها protection و support للوزراء
+
+197
+00:15:11,150 --> 00:15:16,570
+في ال interior part قلنا في
+
+198
+00:15:16,570 --> 00:15:24,450
+ال anterior part of the pelvic طبعا فيه إنا اثنين
+
+199
+00:15:24,450 --> 00:15:28,930
+إضام على الناحي هذه على اليمين وعلى اليسار هدولة
+
+200
+00:15:28,930 --> 00:15:32,410
+عبارة عن تلت إضام ملتحمة بتعمل articulation مع ال
+
+201
+00:15:32,410 --> 00:15:38,550
+scapulaبالخلف بنسميهم احنا left and right ossa
+
+202
+00:15:38,550 --> 00:15:48,390
+coccia بسموهم
+
+203
+00:15:48,390 --> 00:15:53,750
+ال head bones ال ossococci في عندنا تلاتة
+
+204
+00:15:53,750 --> 00:15:59,010
+separated bone هي ال alienاللي هي العضمة الكبيرة
+
+205
+00:15:59,010 --> 00:16:03,070
+العريضة اللي عاملة flare كده وفي عندنا ال Pupis
+
+206
+00:16:03,070 --> 00:16:07,290
+اللي بتكون العضمة الأمامية وفي عندنا ال ischium هي
+
+207
+00:16:07,290 --> 00:16:13,130
+العضمة اللي احنا لما في حالة الجلوس بنقعد عليها
+
+208
+00:16:22,290 --> 00:16:27,310
+طبعا في عندنا بالرسم موضح كل أجزاء ال .. ال pelvic
+
+209
+00:16:27,310 --> 00:16:31,990
+bones أو ال .. ال hip bones يعني احنا أكتر ما
+
+210
+00:16:31,990 --> 00:16:35,170
+بيهمنا ال anterior superior iliac spine لإنها
+
+211
+00:16:35,170 --> 00:16:38,510
+بتعمل attachments للعدلات و في عندنا ال posterior
+
+212
+00:16:38,510 --> 00:16:43,950
+superior iliac spine و في طبعا في عندنا many
+
+213
+00:16:43,950 --> 00:16:48,720
+foramens موجودةand notches موجودة هادية و فساية
+
+214
+00:16:48,720 --> 00:16:53,980
+موجودة على أساس تعملي attachment للعضلات و أهم
+
+215
+00:16:53,980 --> 00:17:00,460
+مكونات موجودة هي ال attachments
+
+216
+00:17:00,460 --> 00:17:03,880
+مع ال head ال acetabulum اللى بتعمل attachments مع
+
+217
+00:17:03,880 --> 00:17:11,410
+ال head of a humerus sorry of فيمرفي هنا ال paper
+
+218
+00:17:11,410 --> 00:17:15,670
+synthesis كمان في هذا المنطقة منطقة التحام قلنا في
+
+219
+00:17:15,670 --> 00:17:18,590
+عندنا cartilage هنا ال cartilage هذا هي منطقة
+
+220
+00:17:18,590 --> 00:17:23,630
+التحام ال two hip او two pubic bone الموجودين طبعا
+
+221
+00:17:23,630 --> 00:17:26,850
+هنا الفرمين هذا الموجود هو الفرم اللي بيعمل
+
+222
+00:17:26,850 --> 00:17:30,430
+passage ل ال baby during delivery
+
+223
+00:17:45,010 --> 00:17:47,970
+طبعا احنا زي ما رينا على ال slide كله بنكون شرحنا
+
+224
+00:17:47,970 --> 00:17:52,810
+على ال skeleton فى عندنا ال pubic arch فى عندنا ال
+
+225
+00:17:52,810 --> 00:17:56,370
+skeletoparasite اللى بالاسكم ال skeletoparasite
+
+226
+00:17:56,370 --> 00:18:05,890
+اللى هي العضمة اللى احنا بنقعد عليها عادة ال pubic
+
+227
+00:18:05,890 --> 00:18:09,850
+arch اللى ابتدت الفرامين الفرامين اللى موجود هنا
+
+228
+00:18:09,850 --> 00:18:14,640
+حد بعملى passage لل nerve suppliesلل nerve and
+
+229
+00:18:14,640 --> 00:18:16,380
+vascular supplies
+
+230
+00:18:20,400 --> 00:18:24,160
+يعني حاجة اسمها greater and lesser pelvic ال
+
+231
+00:18:24,160 --> 00:18:27,280
+greater pelvic بتكون من ال lumber vertebra
+
+232
+00:18:27,280 --> 00:18:31,320
+posteriorly and iliac bone laterally and abdominal
+
+233
+00:18:31,320 --> 00:18:35,020
+wall anteriorly اللي هو هذا ال greater اللي هو في
+
+234
+00:18:35,020 --> 00:18:40,600
+كل الفذرع بتكون موجودة أما ال lesser فهو عبارة عن
+
+235
+00:18:40,600 --> 00:18:45,380
+ال sacrum و ال coccyx بهدي الخلف من هنا ال lower
+
+236
+00:18:45,380 --> 00:18:49,880
+ilium و ال ischium و ال pupis laterally
+
+237
+00:18:53,140 --> 00:18:57,820
+طبعا فى فرق بين ال male and female belfic، الفرق
+
+238
+00:18:57,820 --> 00:19:03,560
+بينهم هذا خلق لإنه ال female belfic خلق عشان يكون
+
+239
+00:19:03,560 --> 00:19:07,580
+فى passage لجنين
+
+240
+00:19:07,580 --> 00:19:12,380
+أثناء ال delivery فهذا بيكون فى خصائص مختلفة شوية
+
+241
+00:19:12,380 --> 00:19:19,060
+عن ال male belficالفيميل pelvic الاليكبون more
+
+242
+00:19:19,060 --> 00:19:23,540
+flared border hip pubic arch angle greater حتى
+
+243
+00:19:23,540 --> 00:19:27,140
+تسمح passage لال baby more distance between
+
+244
+00:19:27,140 --> 00:19:32,060
+ischial spine and ischial tuberosity وفي عندنا ال
+
+245
+00:19:32,060 --> 00:19:37,100
+sacral curvature shorter and flatter و العضمات
+
+246
+00:19:37,100 --> 00:19:43,470
+طبعتها lighter أخفطبعاها درس توضيحي بين الفرق ما
+
+247
+00:19:43,470 --> 00:19:45,370
+بين ال male and female
+
+248
+00:19:48,300 --> 00:19:51,920
+بالفعل طبعا عضمات ال lower limbs زي ما احنا حكينا
+
+249
+00:19:51,920 --> 00:19:54,660
+الفيمر, patella, tibial, fibula, tarsal,
+
+250
+00:19:54,780 --> 00:19:59,440
+metatarsal and phalanges الفيمر هي longest bone زي
+
+251
+00:19:59,440 --> 00:20:04,280
+ما احنا شايفينها ال largest كمان bone فيها الفوفيا
+
+252
+00:20:04,280 --> 00:20:08,420
+capitis هي في عينا فيها فتحة هنا جوات ال head في
+
+253
+00:20:08,420 --> 00:20:11,540
+المص موجودة بتعمل attachments لإيليوفيمرال
+
+254
+00:20:11,540 --> 00:20:15,020
+ligament فيها الجريتر اتنوكنتر فيها ال head طبعا
+
+255
+00:20:15,020 --> 00:20:20,850
+فيها ال neck فيها الجريتر اتنوكنترالتركنتر و في
+
+256
+00:20:20,850 --> 00:20:24,870
+عندنا ال Lena Aspera اللى بيعمل attachment هى
+
+257
+00:20:24,870 --> 00:20:30,690
+شايفينه هنا احنا كده بيعطينا attachment ل ال ال
+
+258
+00:20:30,690 --> 00:20:36,450
+quadriceps muscles و فيها ال condyles و ال epi
+
+259
+00:20:36,450 --> 00:20:40,070
+condyles اللى هى قولنا Epi condyles فى عندنا على
+
+260
+00:20:40,070 --> 00:20:43,450
+طرفين ال condyles فى عندنا بروز صغير بنسمي Epi
+
+261
+00:20:43,450 --> 00:20:47,540
+condylesأما البتلة فهي الـ kneecap نسميها الـ
+
+262
+00:20:47,540 --> 00:20:50,380
+anterior surface of the knee بلاد من نوعها
+
+263
+00:20:50,380 --> 00:20:55,980
+sesamoid bone بتكون محاطة بتندن of quadriceps
+
+264
+00:20:55,980 --> 00:21:02,740
+التيبيا بتكون من الشافتأو ال chin ال chin في إلها
+
+265
+00:21:02,740 --> 00:21:08,220
+بروز كده طبعا هي ال media ال bone اللي في إلها
+
+266
+00:21:08,220 --> 00:21:10,880
+gonditis و tibial tuberosity عشان ال tibial
+
+267
+00:21:10,880 --> 00:21:14,760
+tuberosity موجودة هنا عشان تعمل attachment ل ال
+
+268
+00:21:14,760 --> 00:21:19,440
+quadriceps tendon أو ال tendon بطلائي و في عندها
+
+269
+00:21:19,440 --> 00:21:22,060
+إلها ال anterior crest كمان في إلها media
+
+270
+00:21:22,060 --> 00:21:25,720
+الmalolus اللي هي احنا كلنا لو حسينا
+
+271
+00:21:28,890 --> 00:21:32,370
+فحنلاقي هنا فيه بروز هذا البروز اسمه ال medial
+
+272
+00:21:32,370 --> 00:21:35,250
+malleolus وفيه كمان بروز للفيبيولا اسمها ال
+
+273
+00:21:35,250 --> 00:21:39,970
+lateral malleolus أما الفيبيولا فهي بيروح عن ال
+
+274
+00:21:39,970 --> 00:21:42,890
+lateral bone و long cylindrical head هذه non
+
+275
+00:21:42,890 --> 00:21:46,430
+-weight bearing bone مابتحملش أي weight bearing
+
+276
+00:21:46,430 --> 00:21:50,430
+عشان هي لو انكسرت مابتأثر كتير على المشي إلا من
+
+277
+00:21:50,430 --> 00:21:56,000
+خلال الال ankle foots طبعا ال ankle and foot في
+
+278
+00:21:56,000 --> 00:22:01,380
+عندنا عدد من العظام تقريبا في عندنا اربعتاشر ترث
+
+279
+00:22:01,380 --> 00:22:04,920
+البون هي ال calcaneus و التاليوس و ال navicular و
+
+280
+00:22:04,920 --> 00:22:08,080
+الكيوبيد و الكيوبايد و عندنا ال lateral cuneiform
+
+281
+00:22:08,080 --> 00:22:11,240
+و ال intermediate cuneiform و ال medial cuneiform
+
+282
+00:22:11,240 --> 00:22:15,220
+كلهم هدولة تكونوا مواضحين على ال skeleton بهذا
+
+283
+00:22:15,220 --> 00:22:21,370
+الشكل زي ما احنا شايفينطبعا ال metatarsals فى
+
+284
+00:22:21,370 --> 00:22:25,210
+عندنا ten metatarsals بقول خمسة على اليمين و خمسة
+
+285
+00:22:25,210 --> 00:22:30,010
+على اليسار و فى عندنا الفلانجز زى ما قولنا فى
+
+286
+00:22:30,010 --> 00:22:38,430
+عندنا ال four lateral toys فىهم تلات لانجز اللى هى
+
+287
+00:22:38,430 --> 00:22:42,050
+ال proximal, intermediate and distal اما ال thumb
+
+288
+00:22:42,050 --> 00:22:48,150
+فهو only two flanges بالظبط نفس تركيبة ال upper ال
+
+289
+00:22:48,150 --> 00:22:48,410
+hand
+
+290
+00:22:51,900 --> 00:22:55,040
+طبعا في حاجة اسمها arches of the foot لو لاحظنا
+
+291
+00:22:55,040 --> 00:22:58,480
+أنه كلنا طلعنا على أسفل القدم عندنا فبنلاقي فيه
+
+292
+00:22:58,480 --> 00:23:02,840
+arch في عندنا medial arch موجود على الناحية اليمين
+
+293
+00:23:02,840 --> 00:23:05,360
+هو أنا ال skeleton اللي عندي هنا مشوّه شوية بس أنا
+
+294
+00:23:05,360 --> 00:23:09,320
+بقدر أو أوضح هنا أنه في هنا ال medial arch وفي هنا
+
+295
+00:23:09,320 --> 00:23:13,400
+slightly lateral أصغر منه شوية lateral arch ماعرفش
+
+296
+00:23:13,400 --> 00:23:18,310
+إذا واضح بالصورة أو لأ وفي عندنا كمانفي transverse
+
+297
+00:23:18,310 --> 00:23:22,050
+arch هدول إيش وظيفتهم ال arches هدول يعملوا عملية
+
+298
+00:23:22,050 --> 00:23:25,930
+shock absorption عشان العضام الرجل مش كل منطوب
+
+299
+00:23:25,930 --> 00:23:29,330
+بالأرض يكون فيه تاخد ضربة هذه بتعمل shock
+
+300
+00:23:29,330 --> 00:23:35,630
+absorption يعني تبص الصدمات على العضام ال foot
+
+301
+00:23:35,630 --> 00:23:38,430
+طبعا في ناس عندهم flat foot عندنا هنقول من إيش
+
+302
+00:23:38,430 --> 00:23:42,640
+هدول ممكن يعنيطبعا ال soul of the foot does not
+
+303
+00:23:42,640 --> 00:23:47,100
+rest flat on the ground في عندنا .. ليش؟ ليش
+
+304
+00:23:47,100 --> 00:23:49,880
+بيكونش flat؟ بيكون في عندنا عرش support the weight
+
+305
+00:23:49,880 --> 00:23:53,540
+of the body طبعا بيكون في عندنا blood vessels
+
+306
+00:23:53,540 --> 00:23:57,000
+موجودة في ال soul of the foot لو كانت الأجر بتنزل
+
+307
+00:23:57,000 --> 00:24:01,540
+flat على الأرض فبصير في عندنا squeezing أو ضغط على
+
+308
+00:24:01,540 --> 00:24:05,200
+ال vessels هذه فهذه ممكن أنها تقلل الدورة الدموية
+
+309
+00:24:05,200 --> 00:24:08,480
+عشان هيك بتكون مقوسة عشان لما احنا نزل رجلنا على
+
+310
+00:24:08,480 --> 00:24:13,690
+الأرضما تنزلش flat تضغط الأوعية الدموية
+
+311
+00:24:18,340 --> 00:24:22,660
+طبعا على ال powerpoint موضحة ال arches في عندنا
+
+312
+00:24:22,660 --> 00:24:26,520
+بعض المشاكل اللي بتصيب ال lower limb أو ال foot
+
+313
+00:24:26,520 --> 00:24:30,400
+بالذات في حاجة اسمها halox valgus تلاحظ ان بعض
+
+314
+00:24:30,400 --> 00:24:37,480
+الناس ممكن يصير في خلل في تركيبة ال first toys toy
+
+315
+00:24:37,480 --> 00:24:42,560
+اللي هو ال halox احنا بنسميه بيصير فيه deviationof
+
+316
+00:24:42,560 --> 00:24:45,780
+the greater to add the metatarsal phalangeal joint
+
+317
+00:24:45,780 --> 00:24:50,720
+طبعا ال incidence أكتر في ال women من ال men بنتج
+
+318
+00:24:50,720 --> 00:24:53,480
+عن ال bad lifted foods طبعا في ال food أنتوا
+
+319
+00:24:53,480 --> 00:24:56,400
+عارفينها اللي هي ال .. ال .. ال .. البوز الرفيع
+
+320
+00:24:56,400 --> 00:25:01,120
+هذه فبتلاقي الأصابع بتكون كده يعني مضغوطة جواها
+
+321
+00:25:01,120 --> 00:25:05,350
+فعلى ال long term ممكن تعملنا مشاكلأو ممكن يكون في
+
+322
+00:25:05,350 --> 00:25:10,770
+عندنا short لل first metatarsal بتأدي لهذه المشكلة
+
+323
+00:25:10,770 --> 00:25:13,850
+طبعا إذا صارت ال deformity هادي موجودة فمعناها هي
+
+324
+00:25:13,850 --> 00:25:18,530
+أنها ممكن أنها تتطور تطور نتيجة pull of the
+
+325
+00:25:18,530 --> 00:25:23,180
+muscles around the halluxطبعا في ال halox rigidus
+
+326
+00:25:23,180 --> 00:25:26,280
+ممكن يصير فيه calcification على ال
+
+327
+00:25:26,280 --> 00:25:29,220
+metatarsophalangeal joints أو osteoarthritic
+
+328
+00:25:29,220 --> 00:25:35,580
+exchanges فممكن هذه تعملي painful and stiff toy،
+
+329
+00:25:35,580 --> 00:25:39,610
+big toyفي ال bisplanas الناس اللي بنسموهم ال flat
+
+330
+00:25:39,610 --> 00:25:44,010
+foots هدولة أجرهم بتكون ال arches كلها ممسوحة
+
+331
+00:25:44,010 --> 00:25:49,550
+فبتنزل رجلهم على الأرض مباشرة، هذا عبارة عن
+
+332
+00:25:49,550 --> 00:25:53,350
+depression أو collapse لل longitudinal arch،
+
+333
+00:25:53,350 --> 00:25:58,310
+result ال four foot كلها بتكون laterally بتروحعلى
+
+334
+00:25:58,310 --> 00:26:03,190
+الناحية ال laterally ال head of the talus no
+
+335
+00:26:03,190 --> 00:26:07,190
+longer supported the cause of a flat foot both
+
+336
+00:26:07,190 --> 00:26:11,110
+congenital or acquired congenital انه بنولد لإن هو
+
+337
+00:26:11,110 --> 00:26:14,730
+من عائلة عندهم flat foot او acquired لإن في عندنا
+
+338
+00:26:14,940 --> 00:26:19,180
+ال .. الفوض ال .. ال .. الشوذ اللي بتستخدم دائما
+
+339
+00:26:19,180 --> 00:26:23,180
+ممكن تكون منذ الطفولة سيئة فبتأثر هذا و أعطيكم
+
+340
+00:26:23,180 --> 00:26:25,800
+العافية و أرجو أن أكون أوشظت في مجال ال
+
+341
+00:26:25,800 --> 00:26:28,900
+appendicular system و المشاكل اللي ممكن تصيب الفوض
+
+342
+00:26:28,900 --> 00:26:30,380
+السلام عليكم و رحمة الله
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..c7059701e1305bfc6e1b42a9f66a94f6185580fa
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 2915, "start": 4.93, "end": 29.15, "text": "باسم الله الرحمن الرحيم والصلاة والسلام علي سيدنا محمد سيد المرسلين وعلى الله هو صح بيه أجمعين طبعا اليوم هنستكمل في مساق التشريح في ال skeletal system الجزء التالت هنتكلم عن ال appendicular system و اليوم انا اخترت ان يكون معنا ال skeleton عشان نراجع ال axial skeleton وبالتالي ننزل لل appendicular skeleton", "tokens": [3555, 32277, 2304, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 16070, 9381, 15040, 3660, 16070, 3794, 37440, 25894, 8608, 25708, 8315, 3714, 35571, 3215, 8608, 25708, 9673, 2288, 3794, 1211, 9957, 4032, 3615, 23942, 21984, 31439, 20328, 5016, 4724, 1829, 3224, 5551, 7435, 2304, 3615, 9957, 23032, 3555, 3615, 995, 45595, 20498, 8032, 1863, 14851, 24793, 1211, 8978, 47524, 995, 4587, 16712, 8592, 16572, 5016, 8978, 2423, 32321, 304, 1185, 25724, 11622, 38207, 16712, 6027, 2655, 8032, 29399, 4117, 19528, 18871, 2423, 34116, 14646, 1185, 4032, 45595, 20498, 1975, 8315, 1975, 46456, 43500, 16472, 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"probability": 0.943359375}, {"start": 286.82, "end": 287.08, "word": " اللي", "probability": 0.950927734375}, {"start": 287.08, "end": 287.22, "word": " ال", "probability": 0.281982421875}, {"start": 287.22, "end": 287.98, "word": " calcaneus", "probability": 0.8101806640625}, {"start": 287.98, "end": 288.4, "word": " و", "probability": 0.625}, {"start": 288.4, "end": 288.52, "word": " ال", "probability": 0.74755859375}, {"start": 288.52, "end": 289.02, "word": " talus", "probability": 0.96728515625}, {"start": 289.02, "end": 289.2, "word": " و", "probability": 0.9794921875}, {"start": 289.2, "end": 289.36, "word": " في", "probability": 0.57666015625}, {"start": 289.36, "end": 290.1, "word": " عندنا", "probability": 0.969482421875}, {"start": 290.1, "end": 290.54, "word": " ال", "probability": 0.857421875}, {"start": 290.54, "end": 293.3, "word": " metatarsals", "probability": 0.713623046875}], "temperature": 1.0}, {"id": 15, "seek": 30516, "start": 293.94, "end": 305.16, "text": "وفي عندنا الفلانجيز وهذه برضه نفس تقسيمات ال upper limb هنتعرف عليهم واحدة واحدة من خلال محاضرتنا لليوم، طيب نشوف إيش؟", "tokens": [2407, 41185, 43242, 8315, 27188, 1211, 7649, 7435, 1829, 11622, 37037, 24192, 4724, 43042, 3224, 8717, 36178, 6055, 4587, 3794, 32640, 9307, 2423, 6597, 30390, 8032, 29399, 3615, 28480, 25894, 16095, 36764, 24401, 3660, 36764, 24401, 3660, 9154, 16490, 1211, 6027, 3714, 5016, 46958, 43500, 8315, 5296, 20292, 20498, 12399, 23032, 1829, 3555, 8717, 8592, 38688, 11933, 1829, 8592, 22807], "avg_logprob": -0.26408810107434383, "compression_ratio": 1.361842105263158, "no_speech_prob": 1.1920928955078125e-07, "words": [{"start": 293.94, "end": 294.26, "word": "وفي", "probability": 0.6170654296875}, {"start": 294.26, "end": 294.66, "word": " عندنا", "probability": 0.735595703125}, {"start": 294.66, "end": 295.5, "word": " الفلانجيز", "probability": 0.80072021484375}, {"start": 295.5, "end": 296.0, "word": " وهذه", "probability": 0.6494140625}, {"start": 296.0, "end": 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Pupis اللي بتكون العضمة الأمامية وفي عندنا ال ischium هي العضمة اللي احنا لما في حالة الجلوس بنقعد عليها", "tokens": [6027, 20292, 39896, 18863, 11242, 46007, 33251, 3555, 48923, 18863, 16572, 11242, 3660, 13672, 1829, 6225, 10943, 37977, 32446, 9122, 3215, 3224, 4032, 41185, 43242, 8315, 2423, 430, 1010, 271, 13672, 1829, 39894, 30544, 18863, 11242, 46007, 16247, 2304, 10943, 10632, 4032, 41185, 43242, 8315, 2423, 307, 339, 2197, 39896, 18863, 11242, 46007, 13672, 1829, 1975, 5016, 8315, 5296, 15042, 8978, 11331, 6027, 3660, 25724, 1211, 41779, 44945, 4587, 22488, 25894, 11296], "avg_logprob": -0.15378853229627218, "compression_ratio": 1.830188679245283, "no_speech_prob": 0.0, "words": [{"start": 957.87, "end": 958.09, "word": "اللي", "probability": 0.89697265625}, {"start": 958.09, "end": 958.19, "word": " هي", "probability": 0.9189453125}, {"start": 958.19, "end": 958.53, "word": " العضمة", "probability": 0.9150390625}, {"start": 958.53, "end": 959.01, "word": " الكبيرة", 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two", "probability": 0.9423828125}, {"start": 1363.59, "end": 1364.27, "word": " flanges", "probability": 0.845703125}, {"start": 1364.27, "end": 1364.83, "word": " بالظبط", "probability": 0.8846435546875}, {"start": 1364.83, "end": 1365.05, "word": " نفس", "probability": 0.94677734375}, {"start": 1365.05, "end": 1365.65, "word": " تركيبة", "probability": 0.9285888671875}, {"start": 1365.65, "end": 1366.15, "word": " ال", "probability": 0.955078125}, {"start": 1366.15, "end": 1366.75, "word": " upper", "probability": 0.86328125}, {"start": 1366.75, "end": 1368.15, "word": " ال", "probability": 0.810546875}, {"start": 1368.15, "end": 1368.41, "word": " hand", "probability": 0.74267578125}], "temperature": 1.0}, {"id": 59, "seek": 139652, "start": 1371.9, "end": 1396.52, "text": "طبعا في حاجة اسمها arches of the foot لو لاحظنا أنه كلنا طلعنا على أسفل القدم عندنا فبنلاقي فيه arch في عندنا medial arch موجود على الناحية اليمين هو أنا ال skeleton اللي عندي هنا مشوّه شوية بس أنا بقدر أو أوضح هنا أنه في هنا ال medial arch وفي هنا slightly lateral أصغر منه شوية lateral arch ماعرفش إذا واضح بالصورة أو لأ وفي عندنا كمان", "tokens": [9566, 3555, 3615, 995, 8978, 11331, 26108, 3660, 24525, 2304, 11296, 594, 3781, 295, 264, 2671, 45164, 20193, 5016, 19913, 8315, 14739, 3224, 28242, 8315, 23032, 1211, 3615, 8315, 15844, 5551, 3794, 5172, 1211, 25062, 40448, 43242, 8315, 6156, 3555, 1863, 15040, 38436, 8978, 3224, 3912, 8978, 43242, 8315, 1205, 831, 3912, 3714, 29245, 23328, 15844, 2423, 8315, 5016, 10632, 2423, 32640, 9957, 31439, 41850, 2423, 25204, 13672, 1829, 18871, 16254, 34105, 37893, 2407, 11703, 3224, 13412, 2407, 10632, 4724, 3794, 41850, 4724, 28543, 2288, 34051, 5551, 2407, 11242, 5016, 34105, 14739, 3224, 8978, 34105, 2423, 1205, 831, 3912, 4032, 41185, 34105, 4748, 25128, 5551, 9381, 17082, 2288, 9154, 3224, 13412, 2407, 10632, 25128, 3912, 19446, 3615, 28480, 8592, 11933, 15730, 4032, 46958, 5016, 20666, 9381, 13063, 3660, 34051, 5296, 10721, 4032, 41185, 43242, 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طبعا في ناس عندهم flat foot عندنا هنقول من إيش هدول ممكن يعني", "tokens": [41185, 1145, 4308, 3912, 8032, 3215, 12610, 11933, 1829, 8592, 4032, 19913, 33911, 2655, 16095, 2423, 594, 3781, 8032, 3215, 12610, 7251, 25957, 1211, 14407, 6225, 42213, 10632, 5588, 27557, 6225, 8592, 7649, 18863, 11242, 10943, 34892, 7435, 1211, 37893, 28242, 9154, 9566, 37746, 20666, 10721, 43042, 7251, 30544, 8978, 3224, 6055, 47283, 3215, 48812, 25513, 3660, 29538, 39894, 25957, 1211, 5588, 27557, 37495, 22653, 6055, 3555, 9381, 31767, 40448, 9307, 15844, 18863, 11242, 10943, 2423, 2671, 23032, 3555, 3615, 995, 8978, 8717, 32277, 43242, 16095, 4962, 2671, 43242, 8315, 8032, 1863, 39648, 9154, 11933, 1829, 8592, 8032, 3215, 12610, 3714, 43020, 37495, 22653], "avg_logprob": -0.18422618479955763, "compression_ratio": 1.6926229508196722, "no_speech_prob": 1.7881393432617188e-07, "words": [{"start": 1396.99, "end": 1397.39, "word": "في", "probability": 0.81396484375}, {"start": 1397.39, "end": 1398.31, "word": 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toy اللي هو ال halox احنا بنسميه بيصير فيه deviation", "tokens": [9566, 3555, 3615, 995, 15844, 2423, 1347, 6053, 3714, 2407, 11242, 5016, 3660, 2423, 594, 3781, 8978, 43242, 8315, 45030, 11242, 9673, 8592, 995, 28820, 13672, 1829, 39894, 9381, 1829, 3555, 2423, 3126, 30390, 34051, 2423, 2671, 20666, 8848, 9307, 8978, 11331, 26108, 3660, 24525, 2304, 11296, 7523, 5230, 1323, 21956, 6055, 15040, 5016, 19913, 16472, 45030, 11242, 2423, 8315, 3794, 3714, 43020, 7251, 9381, 13546, 8978, 16490, 1211, 1211, 8978, 6055, 31747, 1829, 49401, 2423, 700, 13753, 12058, 13672, 1829, 31439, 2423, 7523, 5230, 1975, 5016, 8315, 44945, 38251, 1829, 3224, 4724, 1829, 9381, 13546, 8978, 3224, 25163], "avg_logprob": -0.19031249552965165, "compression_ratio": 1.6343612334801763, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 1458.34, "end": 1458.74, "word": "طبعا", "probability": 0.953369140625}, {"start": 1458.74, "end": 1458.92, "word": " على", "probability": 0.7529296875}, {"start": 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men بنتج عن ال bad lifted foods طبعا في ال food أنتوا عارفينها اللي هي ال .. ال .. ال .. البوز الرفيع هذه فبتلاقي الأصابع بتكون كده يعني مضغوطة جواها فعلى ال long term ممكن تعملنا مشاكل", "tokens": [2670, 264, 5044, 281, 909, 264, 1131, 267, 685, 304, 903, 304, 933, 304, 7225, 23032, 3555, 3615, 995, 2423, 41726, 5551, 4117, 2655, 2288, 8978, 2423, 2266, 9154, 2423, 1706, 44945, 2655, 7435, 18871, 2423, 1578, 17854, 8656, 23032, 3555, 3615, 995, 8978, 2423, 1755, 14739, 2655, 14407, 6225, 9640, 5172, 9957, 11296, 13672, 1829, 39896, 2423, 4386, 2423, 4386, 2423, 4386, 29739, 2407, 11622, 2423, 28480, 40228, 29538, 6156, 3555, 2655, 15040, 38436, 16247, 9381, 16758, 3615, 39894, 30544, 9122, 3215, 3224, 37495, 22653, 3714, 11242, 17082, 2407, 9566, 3660, 10874, 14407, 11296, 6156, 3615, 23942, 2423, 938, 1433, 3714, 43020, 6055, 25957, 1211, 8315, 37893, 995, 28820], "avg_logprob": -0.18060247506107296, "compression_ratio": 1.5992217898832686, "no_speech_prob": 1.1920928955078125e-06, 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هدولة", "probability": 0.8199462890625}, {"start": 1540.55, "end": 1541.01, "word": " أجرهم", "probability": 0.8448486328125}, {"start": 1541.01, "end": 1541.47, "word": " بتكون", "probability": 0.955078125}, {"start": 1541.47, "end": 1542.03, "word": " ال", "probability": 0.68701171875}, {"start": 1542.03, "end": 1542.53, "word": " arches", "probability": 0.86328125}, {"start": 1542.53, "end": 1543.13, "word": " كلها", "probability": 0.986083984375}, {"start": 1543.13, "end": 1544.01, "word": " ممسوحة", "probability": 0.9642740885416666}, {"start": 1544.01, "end": 1544.55, "word": " فبتنزل", "probability": 0.9192708333333334}, {"start": 1544.55, "end": 1544.99, "word": " رجلهم", "probability": 0.9678955078125}, {"start": 1544.99, "end": 1545.55, "word": " على", "probability": 0.92138671875}, {"start": 1545.55, "end": 1546.27, "word": " الأرض", "probability": 0.969482421875}, {"start": 1546.27, "end": 1547.47, "word": " مباشرة،", "probability": 0.882763671875}, {"start": 1547.47, "end": 1548.31, "word": " هذا", "probability": 0.6630859375}, {"start": 1548.31, "end": 1549.33, "word": " عبارة", "probability": 0.9969482421875}, {"start": 1549.33, "end": 1549.55, "word": " عن", "probability": 0.99365234375}, {"start": 1549.55, "end": 1550.19, "word": " depression", "probability": 0.89990234375}, {"start": 1550.19, "end": 1550.61, "word": " أو", "probability": 0.85595703125}, {"start": 1550.61, "end": 1551.15, "word": " collapse", "probability": 0.7255859375}, {"start": 1551.15, "end": 1551.35, "word": " لل", "probability": 0.525390625}, {"start": 1551.35, "end": 1551.93, "word": " longitudinal", "probability": 0.471435546875}, {"start": 1551.93, "end": 1553.35, "word": " arch،", "probability": 0.744873046875}, {"start": 1553.35, "end": 1553.91, "word": " result", "probability": 0.732421875}, {"start": 1553.91, "end": 1554.61, "word": " ال", "probability": 0.7529296875}, {"start": 1554.61, "end": 1555.05, "word": " four", "probability": 0.814453125}, {"start": 1555.05, "end": 1555.45, "word": " foot", "probability": 0.85888671875}, {"start": 1555.45, "end": 1555.79, "word": " كلها", "probability": 0.95556640625}, {"start": 1555.79, "end": 1556.25, "word": " بتكون", "probability": 0.98876953125}, {"start": 1556.25, "end": 1557.01, "word": " laterally", "probability": 0.869384765625}, {"start": 1557.01, "end": 1557.55, "word": " بتروح", "probability": 0.810546875}], "temperature": 1.0}, {"id": 68, "seek": 157473, "start": 1557.83, "end": 1574.73, "text": "على الناحية ال laterally ال head of the talus no longer supported the cause of a flat foot both congenital or acquired congenital انه بنولد لإن هو من عائلة عندهم flat foot او acquired لإن في عندنا", "tokens": [3615, 23942, 2423, 8315, 5016, 10632, 2423, 1780, 379, 2423, 1378, 295, 264, 4023, 301, 572, 2854, 8104, 264, 3082, 295, 257, 4962, 2671, 1293, 416, 1766, 1686, 420, 17554, 416, 1766, 1686, 16472, 3224, 44945, 12610, 3215, 5296, 28814, 1863, 31439, 9154, 6225, 16373, 37977, 43242, 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"probability": 0.8837890625}, {"start": 1563.19, "end": 1563.67, "word": " longer", "probability": 0.94970703125}, {"start": 1563.67, "end": 1564.65, "word": " supported", "probability": 0.90576171875}, {"start": 1564.65, "end": 1565.09, "word": " the", "probability": 0.452392578125}, {"start": 1565.09, "end": 1565.59, "word": " cause", "probability": 0.83740234375}, {"start": 1565.59, "end": 1565.79, "word": " of", "probability": 0.98193359375}, {"start": 1565.79, "end": 1565.91, "word": " a", "probability": 0.67529296875}, {"start": 1565.91, "end": 1566.21, "word": " flat", "probability": 0.94482421875}, {"start": 1566.21, "end": 1566.59, "word": " foot", "probability": 0.7470703125}, {"start": 1566.59, "end": 1567.19, "word": " both", "probability": 0.8251953125}, {"start": 1567.19, "end": 1567.87, "word": " congenital", "probability": 0.9612630208333334}, {"start": 1567.87, "end": 1568.19, "word": " or", "probability": 0.96142578125}, {"start": 1568.19, "end": 1568.69, "word": " acquired", "probability": 0.80859375}, {"start": 1568.69, "end": 1569.71, "word": " congenital", "probability": 0.7154134114583334}, {"start": 1569.71, "end": 1569.95, "word": " انه", "probability": 0.6207275390625}, {"start": 1569.95, "end": 1570.39, "word": " بنولد", "probability": 0.9664713541666666}, {"start": 1570.39, "end": 1570.71, "word": " لإن", "probability": 0.779052734375}, {"start": 1570.71, "end": 1571.11, "word": " هو", "probability": 0.6787109375}, {"start": 1571.11, "end": 1571.59, "word": " من", "probability": 0.96728515625}, {"start": 1571.59, "end": 1571.97, "word": " عائلة", "probability": 0.9729817708333334}, {"start": 1571.97, "end": 1572.35, "word": " عندهم", "probability": 0.986328125}, {"start": 1572.35, "end": 1572.67, "word": " flat", "probability": 0.404052734375}, {"start": 1572.67, "end": 1573.11, "word": " foot", "probability": 0.76220703125}, {"start": 1573.11, "end": 1573.33, "word": " او", "probability": 0.786865234375}, {"start": 1573.33, "end": 1573.75, "word": " acquired", "probability": 0.87158203125}, {"start": 1573.75, "end": 1574.15, "word": " لإن", "probability": 0.95556640625}, {"start": 1574.15, "end": 1574.37, "word": " في", "probability": 0.419921875}, {"start": 1574.37, "end": 1574.73, "word": " عندنا", "probability": 0.79931640625}], "temperature": 1.0}, {"id": 69, "seek": 159038, "start": 1574.94, "end": 1590.38, "text": "ال .. الفوض ال .. ال .. الشوذ اللي بتستخدم دائما ممكن تكون منذ الطفولة سيئة فبتأثر هذا و أعطيكم العافية و أرجو أن أكون أوشظت في مجال ال appendicular system و المشاكل اللي ممكن تصيب الفوض السلام عليكم و رحمة الله", "tokens": [6027, 4386, 27188, 2407, 11242, 2423, 4386, 2423, 4386, 25124, 2407, 8848, 13672, 1829, 39894, 14851, 9778, 40448, 11778, 16373, 15042, 3714, 43020, 6055, 30544, 9154, 8848, 41950, 5172, 12610, 3660, 8608, 1829, 19986, 3660, 6156, 3555, 2655, 10721, 49115, 23758, 4032, 5551, 3615, 9566, 1829, 24793, 18863, 31845, 10632, 4032, 5551, 47341, 2407, 14739, 5551, 30544, 34051, 8592, 19913, 2655, 8978, 3714, 7435, 6027, 2423, 34116, 14646, 1185, 4032, 9673, 8592, 995, 28820, 13672, 1829, 3714, 43020, 6055, 9381, 1829, 3555, 27188, 2407, 11242, 21136, 37440, 25894, 24793, 4032, 12602, 35571, 3660, 21984], "avg_logprob": -0.16291118828873885, "compression_ratio": 1.708133971291866, "no_speech_prob": 9.775161743164062e-06, "words": [{"start": 1574.94, "end": 1575.4, "word": "ال", "probability": 0.955078125}, {"start": 1575.4, "end": 1575.64, "word": " ..", "probability": 0.58984375}, {"start": 1575.64, "end": 1576.2, "word": " الفوض", "probability": 0.7661946614583334}, {"start": 1576.2, "end": 1576.52, "word": " ال", "probability": 0.50439453125}, {"start": 1576.52, "end": 1576.64, "word": " ..", "probability": 0.986328125}, {"start": 1576.64, "end": 1577.02, "word": " ال", "probability": 0.82763671875}, {"start": 1577.02, "end": 1577.14, "word": " ..", "probability": 0.6796875}, {"start": 1577.14, "end": 1577.58, "word": " الشوذ", "probability": 0.7584635416666666}, {"start": 1577.58, "end": 1577.72, "word": " اللي", "probability": 0.4736328125}, {"start": 1577.72, "end": 1578.44, "word": " بتستخدم", "probability": 0.8697509765625}, {"start": 1578.44, "end": 1579.18, "word": " دائما", "probability": 0.9015299479166666}, {"start": 1579.18, "end": 1579.54, "word": " ممكن", "probability": 0.98583984375}, {"start": 1579.54, "end": 1579.88, "word": " تكون", "probability": 0.992431640625}, {"start": 1579.88, "end": 1580.16, "word": " منذ", "probability": 0.9345703125}, {"start": 1580.16, "end": 1580.96, "word": " الطفولة", "probability": 0.948486328125}, {"start": 1580.96, "end": 1581.72, "word": " سيئة", "probability": 0.9837646484375}, {"start": 1581.72, "end": 1582.34, "word": " فبتأثر", "probability": 0.94599609375}, {"start": 1582.34, "end": 1582.64, "word": " هذا", "probability": 0.86181640625}, {"start": 1582.64, "end": 1582.8, "word": " و", "probability": 0.8134765625}, {"start": 1582.8, "end": 1583.18, "word": " أعطيكم", "probability": 0.83134765625}, {"start": 1583.18, "end": 1583.66, "word": " العافية", "probability": 0.9650065104166666}, {"start": 1583.66, "end": 1583.8, "word": " و", "probability": 0.90576171875}, {"start": 1583.8, "end": 1584.06, "word": " أرجو", "probability": 0.8645833333333334}, {"start": 1584.06, "end": 1584.18, "word": " أن", "probability": 0.74462890625}, {"start": 1584.18, "end": 1584.5, "word": " أكون", "probability": 0.873046875}, {"start": 1584.5, "end": 1585.06, "word": " أوشظت", "probability": 0.70928955078125}, {"start": 1585.06, "end": 1585.24, "word": " في", "probability": 0.9658203125}, {"start": 1585.24, "end": 1585.66, "word": " مجال", "probability": 0.9949544270833334}, {"start": 1585.66, "end": 1585.8, "word": " ال", "probability": 0.98681640625}, {"start": 1585.8, "end": 1586.36, "word": " appendicular", "probability": 0.666259765625}, {"start": 1586.36, "end": 1587.0, "word": " system", "probability": 0.98046875}, {"start": 1587.0, "end": 1587.14, "word": " و", "probability": 0.837890625}, {"start": 1587.14, "end": 1587.58, "word": " المشاكل", "probability": 0.97607421875}, {"start": 1587.58, "end": 1587.72, "word": " اللي", "probability": 0.978759765625}, {"start": 1587.72, "end": 1587.98, "word": " ممكن", "probability": 0.995849609375}, {"start": 1587.98, "end": 1588.46, "word": " تصيب", "probability": 0.9913330078125}, {"start": 1588.46, "end": 1588.9, "word": " الفوض", "probability": 0.8922526041666666}, {"start": 1588.9, "end": 1589.56, "word": " السلام", "probability": 0.6953125}, {"start": 1589.56, "end": 1589.92, "word": " عليكم", "probability": 0.92529296875}, {"start": 1589.92, "end": 1590.04, "word": " و", "probability": 0.9833984375}, {"start": 1590.04, "end": 1590.3, "word": " رحمة", "probability": 0.7887369791666666}, {"start": 1590.3, "end": 1590.38, "word": " الله", "probability": 0.94970703125}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1591.147375, "duration_after_vad": 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\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..8b027f539e1c810a8bfb8a55d98be72e1fa9e48b
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/pnF0vxmg1k4_raw.srt
@@ -0,0 +1,1368 @@
+1
+00:00:04,930 --> 00:00:07,310
+باسم الله الرحمن الرحيم والصلاة والسلام علي سيدنا
+
+2
+00:00:07,310 --> 00:00:11,430
+محمد سيد المرسلين وعلى الله هو صح بيه أجمعين طبعا
+
+3
+00:00:11,430 --> 00:00:17,070
+اليوم هنستكمل في مساق التشريح في ال skeletal
+
+4
+00:00:17,070 --> 00:00:19,790
+system الجزء التالت هنتكلم عن ال appendicular
+
+5
+00:00:19,790 --> 00:00:23,010
+system و اليوم انا اخترت ان يكون معنا ال skeleton
+
+6
+00:00:23,010 --> 00:00:26,850
+عشان نراجع ال axial skeleton وبالتالي ننزل لل
+
+7
+00:00:26,850 --> 00:00:32,790
+appendicular skeletonالحقيقة احنا حكينا انه ال
+
+8
+00:00:32,790 --> 00:00:36,450
+axle skeleton بتكون من ال head و ال neck و ال
+
+9
+00:00:36,450 --> 00:00:41,490
+vertebral column و ال ..ال rib cage يعني او ال
+
+10
+00:00:41,490 --> 00:00:45,530
+trunk هنا احنا بنسميه ال trunk وقلنا انه موجود على
+
+11
+00:00:45,530 --> 00:00:50,630
+ال axial skeleton موجود عندنا ال pectoral girdle و
+
+12
+00:00:50,630 --> 00:00:54,030
+عندنا ال pelvic girdle اللي بيكونوا مكون أساسي
+
+13
+00:00:54,030 --> 00:00:57,630
+لمحاضرتنا اليوم اللي هي ال abdicular system اللي
+
+14
+00:00:57,630 --> 00:01:01,210
+هو بتتكون من ال upper limb و lower limb مع ال
+
+15
+00:01:01,210 --> 00:01:05,580
+pectoral girdle و pelvic girdleطبعا إحنا شايفين
+
+16
+00:01:05,580 --> 00:01:09,040
+إنه قدامنا زي ما إحنا شايفين في ال skeleton لو
+
+17
+00:01:09,040 --> 00:01:14,080
+أجينا أخدنا هذا ال ال lateral view فبنلاقي إنه في
+
+18
+00:01:14,080 --> 00:01:18,720
+عندنا ال neck ال head و في عندنا lordosis ناحية ال
+
+19
+00:01:18,720 --> 00:01:23,080
+cervical column و عندنا kyphosis ناحية إذا نرجع
+
+20
+00:01:23,080 --> 00:01:25,980
+شوية المحاضرة اللي فاتت kyphosis من ناحية ال
+
+21
+00:01:25,980 --> 00:01:30,960
+thoracicوفى عندنا ال lordosis على ال lumber وفى
+
+22
+00:01:30,960 --> 00:01:37,420
+عندنا ال sacrum and coccyx وطبعا على ال rib cage
+
+23
+00:01:37,420 --> 00:01:41,800
+موجود عندنا ال scapula and clavicle اللى بترتبط
+
+24
+00:01:41,800 --> 00:01:45,500
+فيهم ال upper limb و كذلك عندنا ال pelvic bone
+
+25
+00:01:45,500 --> 00:01:51,490
+اللى بتعطينى ارتباط مع ال lower extremityهذا
+
+26
+00:01:51,490 --> 00:01:55,470
+بالنسبة للـ axial skeleton لو جينا لمكونات ال
+
+27
+00:01:55,470 --> 00:01:59,850
+appendicular skeleton فبناخد في ال upper part هذا
+
+28
+00:01:59,850 --> 00:02:03,170
+بنسمي احنا ال non-weight peering part في عنا ال
+
+29
+00:02:03,170 --> 00:02:07,750
+scapula anticlepical مكون للpectoral girdle and ال
+
+30
+00:02:07,750 --> 00:02:10,990
+upper limb أنا هشرح اليوم بسرعة عشان احنا نرجع لل
+
+31
+00:02:10,990 --> 00:02:15,530
+slide اللي معنا في عنا ال upper limb فيها عدد من
+
+32
+00:02:15,530 --> 00:02:23,620
+العضام تتكون منعدم ال humorous في عندنا ال radius
+
+33
+00:02:23,620 --> 00:02:27,780
+العضمة المتحركة اللى بتعمل دوران وفي عندنا الانا
+
+34
+00:02:27,780 --> 00:02:32,640
+بتعمل articulation مع ال wrists في عندنا ال eight
+
+35
+00:02:32,640 --> 00:02:37,060
+carpal bonesفي عندنا first row أربع second row
+
+36
+00:02:37,060 --> 00:02:44,160
+أربع في عندنا الميتا carpals وعندنا الفلانجيز طبعا
+
+37
+00:02:44,160 --> 00:02:47,060
+احنا بنعرف أنه في عندنا عدد الفلانجيز في الأربع
+
+38
+00:02:47,060 --> 00:02:51,980
+fingersموجود في ال thumb في عندنا two phalanges
+
+39
+00:02:51,980 --> 00:02:55,960
+وفي الأربع أصابع التانين في عندنا three phalanges
+
+40
+00:02:55,960 --> 00:02:59,980
+نفس التركيب هذا ونفس عدم تقريبا يعني عدد مقارب من
+
+41
+00:02:59,980 --> 00:03:04,080
+العظام موجود في عندنا مشابه له في ال lower limb بس
+
+42
+00:03:04,080 --> 00:03:08,680
+هنا ال lower limb العظام طبعتها أطول شوية يعني
+
+43
+00:03:08,680 --> 00:03:13,260
+قوتها أكبر ليش؟ لأنها weight bearing bones المعنى
+
+44
+00:03:13,260 --> 00:03:16,840
+أنه إحنا لما بنوقف نوقف على أقدام ال lower limb
+
+45
+00:03:18,030 --> 00:03:24,770
+البلفك هو موجود عبارة عن عضام الاليوم والاسكيان مع
+
+46
+00:03:24,770 --> 00:03:29,930
+البيوبيس بلتحموا مع الساكرام في الخلف هنا بيكونوا
+
+47
+00:03:29,930 --> 00:03:34,170
+خلينا نقول حواضتكون في الـ anterior part في ال
+
+48
+00:03:34,170 --> 00:03:37,070
+upper pelvic موجود في عيننا ال abdominal viscerals
+
+49
+00:03:37,070 --> 00:03:40,210
+وفي ال lower part في عيننا ال genitalia وكمان
+
+50
+00:03:40,210 --> 00:03:44,010
+بيصير في عيننا attachment لإن الوزن بنزل من الرأس
+
+51
+00:03:44,010 --> 00:03:47,950
+لل cervical وبروح على ال trunk و بيجي على ال
+
+52
+00:03:47,950 --> 00:03:52,370
+lumbar و بيصير له توزيع على ال both pelvic bone
+
+53
+00:03:52,370 --> 00:03:56,230
+تمام؟ و بعدها بينزل على ال lower limbs و احنا ال
+
+54
+00:03:56,230 --> 00:04:00,290
+contact مع الأرض بيكون عيننا ال foot طبعا في عيننا
+
+55
+00:04:00,290 --> 00:04:04,570
+ال longestو ال biggest bone in the body زي ال ..
+
+56
+00:04:04,570 --> 00:04:08,810
+اللي هي الفيمر و في إنه كذلك بنحاول إنه .. ان ..
+
+57
+00:04:08,810 --> 00:04:13,570
+ان .. انحط قدامنا ال lower limbفي عندنا في ال
+
+58
+00:04:13,570 --> 00:04:16,390
+anterior part of the knee في عندنا sesamoid bone
+
+59
+00:04:16,390 --> 00:04:19,370
+اللى تسمى ال patella في ال anterior part of the
+
+60
+00:04:19,370 --> 00:04:23,050
+knee وفي عندنا ال tibia و ال tibia هادى هنشرح
+
+61
+00:04:23,050 --> 00:04:27,510
+مكوناتها على الصورة ال tibia و ال fibula احنا
+
+62
+00:04:27,510 --> 00:04:29,970
+قولنا هنا في قلنا في radius لكن في عندنا في lower
+
+63
+00:04:29,970 --> 00:04:32,980
+limb في عندنا ال tibia و ال fibulaالتيبيا هي ال
+
+64
+00:04:32,980 --> 00:04:35,600
+wet bearing bone اما الفيبولا it is a non wet
+
+65
+00:04:35,600 --> 00:04:38,980
+bearing bone بتلتحم هدولة عن طريق ال ankle joint
+
+66
+00:04:38,980 --> 00:04:43,080
+مع ال talus مع ال carpa ال tarsal هلقيتها باختلف
+
+67
+00:04:43,080 --> 00:04:46,520
+اللفظ بنقول عنها tarsal bone في عندنا اللي هي ال
+
+68
+00:04:46,520 --> 00:04:50,540
+bone اللي ال calcaneus و ال talus و في عندنا ال
+
+69
+00:04:50,540 --> 00:04:53,300
+metatarsals
+
+70
+00:04:53,940 --> 00:04:58,140
+وفي عندنا الفلانجيز وهذه برضه نفس تقسيمات ال upper
+
+71
+00:04:58,140 --> 00:05:02,760
+limb هنتعرف عليهم واحدة واحدة من خلال محاضرتنا
+
+72
+00:05:02,760 --> 00:05:09,930
+لليوم، طيب نشوف إيش؟في عيننا على ال slides اليوم
+
+73
+00:05:09,930 --> 00:05:15,590
+هنتكلم عن ال appendicular system اللى هو فى ال
+
+74
+00:05:15,590 --> 00:05:18,570
+upper part of the body ال pictorial girdle
+
+75
+00:05:18,570 --> 00:05:22,150
+attached to the upper limb to the trunk و البلف
+
+76
+00:05:22,150 --> 00:05:25,990
+الجردل زى ما وضحنا attached lower limbupper and
+
+77
+00:05:25,990 --> 00:05:29,110
+lower limbs differs in function لكن هم بيختلفوا في
+
+78
+00:05:29,110 --> 00:05:33,430
+الوظيفة قلنا الإيد عشان احنا نقدر نتناول الأشياء و
+
+79
+00:05:33,430 --> 00:05:37,590
+نتحرك و ناكل و نشرب و نمشط و نلبس أما الرجل ال two
+
+80
+00:05:37,590 --> 00:05:42,650
+lower limbs فهم بي .. مسئولين عن عملية ال
+
+81
+00:05:42,650 --> 00:05:44,650
+ambulation و المشي
+
+82
+00:05:46,890 --> 00:05:50,590
+الـ articulation of the pictorial girdle زي ما
+
+83
+00:05:50,590 --> 00:05:55,190
+احنا شايفين في عندنا ال clavicle هنا و في عندنا ال
+
+84
+00:05:55,190 --> 00:06:00,130
+scapula ال clavicle مع ال scapula في عندنا joint
+
+85
+00:06:00,130 --> 00:06:06,540
+اسمهأكروميو clavicular joint ومع الستيرنم هنا اللي
+
+86
+00:06:06,540 --> 00:06:11,720
+هي عضمة القص فيه sternoclavicular joint تمام؟ وفي
+
+87
+00:06:11,720 --> 00:06:15,380
+عندنا هنا في نهاية في ال lateral part في عندنا
+
+88
+00:06:15,380 --> 00:06:19,480
+حاجة أسمها ال glenoid cavity بتصير تعمل
+
+89
+00:06:19,480 --> 00:06:23,320
+articulation مع ال head of the humerus
+
+90
+00:06:27,990 --> 00:06:32,030
+طبعا زي ما وضحنا ال upper extremity consists of
+
+91
+00:06:32,030 --> 00:06:35,330
+bones of the shoulder girdle, upper arm, lower
+
+92
+00:06:35,330 --> 00:06:39,530
+arm, breast and ham, shoulder girdle made up of
+
+93
+00:06:39,530 --> 00:06:43,110
+scapula and clavicle زي ما احنا وضحنا هنا ال
+
+94
+00:06:43,110 --> 00:06:49,630
+clavicle form only bonya joint with the trunk أما
+
+95
+00:06:49,630 --> 00:06:53,990
+الsterno نسمي الsterno clavicular joint لكن ال ..
+
+96
+00:06:53,990 --> 00:06:57,030
+ال scapula مافيش joint مع ال trunk ال scapula
+
+97
+00:06:57,030 --> 00:07:01,250
+محطوطة حط يعني زي شنكل كده عاملة ال scapula مع ال
+
+98
+00:07:01,250 --> 00:07:06,690
+clavicle و محطوطين كده زي القلقة على ال trunk فال
+
+99
+00:07:06,690 --> 00:07:11,070
+scapula حقيقي فش joint ال joint الوحيد اللي موجود
+
+100
+00:07:11,070 --> 00:07:17,430
+فيها هنا مع ال .. ال ..الـ acromioclavicular joint
+
+101
+00:07:17,430 --> 00:07:21,370
+وهذا الـ joint أصلا مع ال upper limb بعيد عن ال
+
+102
+00:07:21,370 --> 00:07:26,410
+trunk الـ
+
+103
+00:07:26,410 --> 00:07:30,730
+pectoral girdle
+
+104
+00:07:30,730 --> 00:07:34,110
+اللي هو مكوناته الأساسية لـ clavicle أو ال scapula
+
+105
+00:07:34,110 --> 00:07:38,790
+وهو طبيعته بيعمل support على ال upper limb
+
+106
+00:07:44,990 --> 00:07:50,250
+هذه شرحناها نروح لل power point اللي عندنا نوضح
+
+107
+00:07:50,250 --> 00:07:56,210
+على زي ما هو مضح على الرسم نقلب ناخد صورة خلفية
+
+108
+00:07:56,210 --> 00:08:00,170
+لأن ال scapula مافيش إمكانية إلا ننظر إليها إلا من
+
+109
+00:08:00,170 --> 00:08:04,250
+القلب فهنا بنلاحظ أن ال scapula ليش مكوناتها فيها
+
+110
+00:08:04,250 --> 00:08:08,250
+spine بينتهي بالacromion ال process هذا و فيها
+
+111
+00:08:08,250 --> 00:08:13,250
+inferiorInfraspinous fossa وفيها Supraspinous
+
+112
+00:08:13,250 --> 00:08:17,450
+fossa هنا وهذه بتعطي attachment للعضلات هنا ال
+
+113
+00:08:17,450 --> 00:08:21,150
+medial border وفي هنا ال apex وفي هنا ال lateral
+
+114
+00:08:21,150 --> 00:08:26,850
+border of the scapula اللي بيروح بيوصل ل .. بيعمل
+
+115
+00:08:26,850 --> 00:08:29,750
+اللي بيكونني في ال lateral part اللي هي ال glenoid
+
+116
+00:08:29,750 --> 00:08:36,530
+كافة اللي بتعمل attachment مع ال .. الhemerasفي
+
+117
+00:08:36,530 --> 00:08:40,350
+حاجة اسمها coracoid process زي احنا شايفينه بهذا
+
+118
+00:08:40,350 --> 00:08:45,050
+المظهر هنا وهذا وظيفته برضه بيعملي muscular
+
+119
+00:08:45,050 --> 00:08:53,950
+attachment أما
+
+120
+00:08:53,950 --> 00:09:00,230
+ال .. ال arm and forearm and the hand بتكونوا
+
+121
+00:09:00,230 --> 00:09:07,940
+تقريبا من thirty bones تلاتين عضمةزي ما احنا وضحنا
+
+122
+00:09:07,940 --> 00:09:11,440
+قبل هيك Humerus Radius and Ulnar and Carpal Bone
+
+123
+00:09:11,440 --> 00:09:17,200
+and Metacarpal and Phalanges تم الـHumerus من
+
+124
+00:09:17,200 --> 00:09:22,580
+صفاتها إنها long bone وهي تقريباً the longest of
+
+125
+00:09:22,580 --> 00:09:27,400
+the upper limb bone Articulated approximately with
+
+126
+00:09:27,400 --> 00:09:32,260
+the Granoid Fossa زي ما احنا شايفين هنا وتحت مع ال
+
+127
+00:09:32,260 --> 00:09:35,900
+Ulna and Radius
+
+128
+00:09:38,660 --> 00:09:47,660
+المكونات هي الـ head و الـ diaphysis و الـ
+
+129
+00:09:47,660 --> 00:09:52,620
+epiphysis
+
+130
+00:09:54,320 --> 00:09:57,940
+يعني بنحب أنه نوضح أنا على الرسم هيكون أوضح و أقرب
+
+131
+00:09:57,940 --> 00:10:01,120
+لإلكوا نحنا نتكلم عن ال tuberosities عن ال groove
+
+132
+00:10:01,120 --> 00:10:07,800
+عن ال bicepital tuberosity نتكلم عن الcapitulum
+
+133
+00:10:07,800 --> 00:10:14,180
+خلنا نوضحها على ال powerpoint ممكن تكون أوضح شويه
+
+134
+00:10:14,180 --> 00:10:17,920
+يبقىتتكوّن من الـ head greater tuberosity لزرد
+
+135
+00:10:17,920 --> 00:10:21,320
+تيابرزوتي في عندنا anatomical neck و في عندنا
+
+136
+00:10:21,320 --> 00:10:26,040
+surgical neck و deltoid tuberosity و الcapitulum و
+
+137
+00:10:26,040 --> 00:10:29,840
+التروكليا و الكورونايد فوسة و الكورونايد فوسة
+
+138
+00:10:29,840 --> 00:10:36,260
+هنشوفها على الرسومات أما ال radius فهي عبارة عن
+
+139
+00:10:36,260 --> 00:10:42,690
+ash longبون موجودة على ال thumb side ايش ال thumb
+
+140
+00:10:42,690 --> 00:10:46,850
+side اللي هو هذا ال side قلنا هنا هلاقي ال radius
+
+141
+00:10:46,850 --> 00:10:52,230
+موجودة ناحية ال thumb أما الألنة موجودة على ال
+
+142
+00:10:52,230 --> 00:10:55,350
+medial part فهي ال most lateral bone
+
+143
+00:10:57,600 --> 00:11:01,560
+الradius طبعا في ال articulation with the
+
+144
+00:11:01,560 --> 00:11:06,360
+capitulum of humerus وفي انحجر اسمها radial notch
+
+145
+00:11:06,360 --> 00:11:10,800
+of ulna هي موجودة بهذه على جنب ال ulna بتعطيني
+
+146
+00:11:10,800 --> 00:11:17,240
+articulation with the head of radius و تفتلي مع ال
+
+147
+00:11:17,240 --> 00:11:20,980
+escapode و ال lunate اللي هم من العضام ال carbal
+
+148
+00:11:20,980 --> 00:11:25,260
+bone في ال first row ال escapode and lunate
+
+149
+00:11:28,060 --> 00:11:34,900
+طبعا ال radius فيها هي ال lateral forearm هون اللي
+
+150
+00:11:34,900 --> 00:11:39,740
+ها head و radial capacity وstelloid process ايش هو
+
+151
+00:11:39,740 --> 00:11:43,100
+الstelloid process احنا لو كنا حطينا ايدنا هنا على
+
+152
+00:11:43,100 --> 00:11:46,960
+منطقة الرسخ بنلاقي ان في عندنا عضمة ايش العضمة هذه
+
+153
+00:11:46,960 --> 00:11:49,840
+حتى لو بنعمل دوران تتحرك معانا هي نسميها
+
+154
+00:11:49,840 --> 00:11:52,600
+الstelloid process اللي هو هذا ال process اللي
+
+155
+00:11:52,600 --> 00:11:57,360
+احنا شايفينه هنا على ال skeleton
+
+156
+00:12:00,900 --> 00:12:04,880
+أما اللي قالنا فهي أيضا long bone موجودة في ناحية
+
+157
+00:12:04,880 --> 00:12:10,080
+ال little finger في هذا الاتجاه يعني احنا بسميها
+
+158
+00:12:10,080 --> 00:12:13,740
+medial bone of the forearm articulated
+
+159
+00:12:13,740 --> 00:12:16,720
+approximately with the humerus and radius and
+
+160
+00:12:16,720 --> 00:12:19,860
+distally with the fibrocartilaginal disk اللي هو
+
+161
+00:12:19,860 --> 00:12:26,670
+موجود في ال wrist joint في هذه المنطقة طبعافي
+
+162
+00:12:26,670 --> 00:12:29,350
+الـTrochlear Notch والأوليكرانون ال process اللي
+
+163
+00:12:29,350 --> 00:12:32,630
+هو هذا احنا كلنا لو حطينا ايدنا هنا على أفق ايدنا
+
+164
+00:12:32,630 --> 00:12:37,990
+بنحس ان في عندنا عضمة العضمة هذه عضمة النهاية او
+
+165
+00:12:37,990 --> 00:12:41,970
+ال epiphysis of the humerus بتسمى الأوليكرانون
+
+166
+00:12:41,970 --> 00:12:49,650
+اللي هي موجودة هنا هذه هيالأوليكرانون طبعا في عنا
+
+167
+00:12:49,650 --> 00:12:55,130
+تركليا عشان تعمل attachment مع الlehumeras وفي عنا
+
+168
+00:12:55,130 --> 00:13:00,630
+ال radial notch أفقالنا الموجودة على الجانب وكذلك
+
+169
+00:13:00,630 --> 00:13:04,470
+في عنا الكورينويد ال process وفي إليها في نهاية
+
+170
+00:13:04,470 --> 00:13:09,190
+العطمة في عنا الacylide process اللي هو hand بهذا
+
+171
+00:13:09,190 --> 00:13:13,490
+الشكل لو حطينا برضه إيدنا هنا هنشعر في نشعر أنه في
+
+172
+00:13:13,490 --> 00:13:20,850
+بروز هنا أو في عطمة بارزةأما ال wrist and hand فإن
+
+173
+00:13:20,850 --> 00:13:23,970
+ال carpal bones في 16 carpal bone تمانية على
+
+174
+00:13:23,970 --> 00:13:27,710
+اليمين و تمانية على ال upper limb ال right and
+
+175
+00:13:27,710 --> 00:13:33,190
+left موزعة في two rows هنشوفهم الآن وفي 10 متر
+
+176
+00:13:33,190 --> 00:13:38,210
+carpal و 28 phalanges في عندنا ال proximal
+
+177
+00:13:38,210 --> 00:13:40,730
+phalange وفي عندنا ال intermediate phalange وفي
+
+178
+00:13:40,730 --> 00:13:45,450
+عندنا ال distal phalange زي ما احنا شايفينطبعا ال
+
+179
+00:13:45,450 --> 00:13:49,870
+carpel bones هم مزعين في two rows في عندنا
+
+180
+00:13:49,870 --> 00:13:52,930
+الترابيزويد والترابيزيوم والسكافويد واللونات ال
+
+181
+00:13:52,930 --> 00:13:58,330
+first row وكمان في عندنا ال second row عبارة عن
+
+182
+00:13:58,330 --> 00:14:03,950
+الكبتات والهامات لأ sorry السكافويد واللونات
+
+183
+00:14:03,950 --> 00:14:08,090
+والبيزيفورمس والتركتريام هدو ال first row اما
+
+184
+00:14:08,090 --> 00:14:11,890
+الترابيزويد والترابيزيوم والكبتات والهامات هما ال
+
+185
+00:14:11,890 --> 00:14:13,110
+second row
+
+186
+00:14:15,930 --> 00:14:21,210
+طبعا لو روحنا ل lower extremity فlower extremity
+
+187
+00:14:21,210 --> 00:14:25,970
+قولنا مكون من ال hip bones فى عندنا ال acetabulum
+
+188
+00:14:25,970 --> 00:14:29,170
+articulated with the head of the humerus فى عندنا
+
+189
+00:14:29,170 --> 00:14:32,050
+ال greater retrocanter اللى شايفينه هنا وعندنا ال
+
+190
+00:14:32,050 --> 00:14:35,690
+lesser retrocanter وهى عبارة عن long bone فى عندنا
+
+191
+00:14:35,690 --> 00:14:40,870
+إلها acres وفى عندها lower part عبارة عن two
+
+192
+00:14:40,870 --> 00:14:48,440
+condylesarticulate with the tibia وبتنتهي كمان
+
+193
+00:14:48,440 --> 00:14:55,700
+بنسميها عضمة ال thigh عضمة الفيمر وفي عندنا ال leg
+
+194
+00:14:55,700 --> 00:14:59,640
+اللي بتتكون من ال two bones و ال ankle and foot
+
+195
+00:14:59,640 --> 00:15:06,290
+روح لل بالفك oneطبعا فيه إنا أربعة من الإضام بتكون
+
+196
+00:15:06,290 --> 00:15:11,150
+ال pelvic bone وضفتها protection و support للوزراء
+
+197
+00:15:11,150 --> 00:15:16,570
+في ال interior part قلنا في
+
+198
+00:15:16,570 --> 00:15:24,450
+ال anterior part of the pelvic طبعا فيه إنا اثنين
+
+199
+00:15:24,450 --> 00:15:28,930
+إضام على الناحي هذه على اليمين وعلى اليسار هدولة
+
+200
+00:15:28,930 --> 00:15:32,410
+عبارة عن تلت إضام ملتحمة بتعمل articulation مع ال
+
+201
+00:15:32,410 --> 00:15:38,550
+scapulaبالخلف بنسميهم احنا left and right ossa
+
+202
+00:15:38,550 --> 00:15:48,390
+coccia بسموهم
+
+203
+00:15:48,390 --> 00:15:53,750
+ال head bones ال ossococci في عندنا تلاتة
+
+204
+00:15:53,750 --> 00:15:59,010
+separated bone هي ال alienاللي هي العضمة الكبيرة
+
+205
+00:15:59,010 --> 00:16:03,070
+العريضة اللي عاملة flare كده وفي عندنا ال Pupis
+
+206
+00:16:03,070 --> 00:16:07,290
+اللي بتكون العضمة الأمامية وفي عندنا ال ischium هي
+
+207
+00:16:07,290 --> 00:16:13,130
+العضمة اللي احنا لما في حالة الجلوس بنقعد عليها
+
+208
+00:16:22,290 --> 00:16:27,310
+طبعا في عندنا بالرسم موضح كل أجزاء ال .. ال pelvic
+
+209
+00:16:27,310 --> 00:16:31,990
+bones أو ال .. ال hip bones يعني احنا أكتر ما
+
+210
+00:16:31,990 --> 00:16:35,170
+بيهمنا ال anterior superior iliac spine لإنها
+
+211
+00:16:35,170 --> 00:16:38,510
+بتعمل attachments للعدلات و في عندنا ال posterior
+
+212
+00:16:38,510 --> 00:16:43,950
+superior iliac spine و في طبعا في عندنا many
+
+213
+00:16:43,950 --> 00:16:48,720
+foramens موجودةand notches موجودة هادية و فساية
+
+214
+00:16:48,720 --> 00:16:53,980
+موجودة على أساس تعملي attachment للعضلات و أهم
+
+215
+00:16:53,980 --> 00:17:00,460
+مكونات موجودة هي ال attachments
+
+216
+00:17:00,460 --> 00:17:03,880
+مع ال head ال acetabulum اللى بتعمل attachments مع
+
+217
+00:17:03,880 --> 00:17:11,410
+ال head of a humerus sorry of فيمرفي هنا ال paper
+
+218
+00:17:11,410 --> 00:17:15,670
+synthesis كمان في هذا المنطقة منطقة التحام قلنا في
+
+219
+00:17:15,670 --> 00:17:18,590
+عندنا cartilage هنا ال cartilage هذا هي منطقة
+
+220
+00:17:18,590 --> 00:17:23,630
+التحام ال two hip او two pubic bone الموجودين طبعا
+
+221
+00:17:23,630 --> 00:17:26,850
+هنا الفرمين هذا الموجود هو الفرم اللي بيعمل
+
+222
+00:17:26,850 --> 00:17:30,430
+passage ل ال baby during delivery
+
+223
+00:17:45,010 --> 00:17:47,970
+طبعا احنا زي ما رينا على ال slide كله بنكون شرحنا
+
+224
+00:17:47,970 --> 00:17:52,810
+على ال skeleton فى عندنا ال pubic arch فى عندنا ال
+
+225
+00:17:52,810 --> 00:17:56,370
+skeletoparasite اللى بالاسكم ال skeletoparasite
+
+226
+00:17:56,370 --> 00:18:05,890
+اللى هي العضمة اللى احنا بنقعد عليها عادة ال pubic
+
+227
+00:18:05,890 --> 00:18:09,850
+arch اللى ابتدت الفرامين الفرامين اللى موجود هنا
+
+228
+00:18:09,850 --> 00:18:14,640
+حد بعملى passage لل nerve suppliesلل nerve and
+
+229
+00:18:14,640 --> 00:18:16,380
+vascular supplies
+
+230
+00:18:20,400 --> 00:18:24,160
+يعني حاجة اسمها greater and lesser pelvic ال
+
+231
+00:18:24,160 --> 00:18:27,280
+greater pelvic بتكون من ال lumber vertebra
+
+232
+00:18:27,280 --> 00:18:31,320
+posteriorly and iliac bone laterally and abdominal
+
+233
+00:18:31,320 --> 00:18:35,020
+wall anteriorly اللي هو هذا ال greater اللي هو في
+
+234
+00:18:35,020 --> 00:18:40,600
+كل الفذرع بتكون موجودة أما ال lesser فهو عبارة عن
+
+235
+00:18:40,600 --> 00:18:45,380
+ال sacrum و ال coccyx بهدي الخلف من هنا ال lower
+
+236
+00:18:45,380 --> 00:18:49,880
+ilium و ال ischium و ال pupis laterally
+
+237
+00:18:53,140 --> 00:18:57,820
+طبعا فى فرق بين ال male and female belfic، الفرق
+
+238
+00:18:57,820 --> 00:19:03,560
+بينهم هذا خلق لإنه ال female belfic خلق عشان يكون
+
+239
+00:19:03,560 --> 00:19:07,580
+فى passage لجنين
+
+240
+00:19:07,580 --> 00:19:12,380
+أثناء ال delivery فهذا بيكون فى خصائص مختلفة شوية
+
+241
+00:19:12,380 --> 00:19:19,060
+عن ال male belficالفيميل pelvic الاليكبون more
+
+242
+00:19:19,060 --> 00:19:23,540
+flared border hip pubic arch angle greater حتى
+
+243
+00:19:23,540 --> 00:19:27,140
+تسمح passage لال baby more distance between
+
+244
+00:19:27,140 --> 00:19:32,060
+ischial spine and ischial tuberosity وفي عندنا ال
+
+245
+00:19:32,060 --> 00:19:37,100
+sacral curvature shorter and flatter و العضمات
+
+246
+00:19:37,100 --> 00:19:43,470
+طبعتها lighter أخفطبعاها درس توضيحي بين الفرق ما
+
+247
+00:19:43,470 --> 00:19:45,370
+بين ال male and female
+
+248
+00:19:48,300 --> 00:19:51,920
+بالفعل طبعا عضمات ال lower limbs زي ما احنا حكينا
+
+249
+00:19:51,920 --> 00:19:54,660
+الفيمر, patella, tibial, fibula, tarsal,
+
+250
+00:19:54,780 --> 00:19:59,440
+metatarsal and phalanges الفيمر هي longest bone زي
+
+251
+00:19:59,440 --> 00:20:04,280
+ما احنا شايفينها ال largest كمان bone فيها الفوفيا
+
+252
+00:20:04,280 --> 00:20:08,420
+capitis هي في عينا فيها فتحة هنا جوات ال head في
+
+253
+00:20:08,420 --> 00:20:11,540
+المص موجودة بتعمل attachments لإيليوفيمرال
+
+254
+00:20:11,540 --> 00:20:15,020
+ligament فيها الجريتر اتنوكنتر فيها ال head طبعا
+
+255
+00:20:15,020 --> 00:20:20,850
+فيها ال neck فيها الجريتر اتنوكنترالتركنتر و في
+
+256
+00:20:20,850 --> 00:20:24,870
+عندنا ال Lena Aspera اللى بيعمل attachment هى
+
+257
+00:20:24,870 --> 00:20:30,690
+شايفينه هنا احنا كده بيعطينا attachment ل ال ال
+
+258
+00:20:30,690 --> 00:20:36,450
+quadriceps muscles و فيها ال condyles و ال epi
+
+259
+00:20:36,450 --> 00:20:40,070
+condyles اللى هى قولنا Epi condyles فى عندنا على
+
+260
+00:20:40,070 --> 00:20:43,450
+طرفين ال condyles فى عندنا بروز صغير بنسمي Epi
+
+261
+00:20:43,450 --> 00:20:47,540
+condylesأما البتلة فهي الـ kneecap نسميها الـ
+
+262
+00:20:47,540 --> 00:20:50,380
+anterior surface of the knee بلاد من نوعها
+
+263
+00:20:50,380 --> 00:20:55,980
+sesamoid bone بتكون محاطة بتندن of quadriceps
+
+264
+00:20:55,980 --> 00:21:02,740
+التيبيا بتكون من الشافتأو ال chin ال chin في إلها
+
+265
+00:21:02,740 --> 00:21:08,220
+بروز كده طبعا هي ال media ال bone اللي في إلها
+
+266
+00:21:08,220 --> 00:21:10,880
+gonditis و tibial tuberosity عشان ال tibial
+
+267
+00:21:10,880 --> 00:21:14,760
+tuberosity موجودة هنا عشان تعمل attachment ل ال
+
+268
+00:21:14,760 --> 00:21:19,440
+quadriceps tendon أو ال tendon بطلائي و في عندها
+
+269
+00:21:19,440 --> 00:21:22,060
+إلها ال anterior crest كمان في إلها media
+
+270
+00:21:22,060 --> 00:21:25,720
+الmalolus اللي هي احنا كلنا لو حسينا
+
+271
+00:21:28,890 --> 00:21:32,370
+فحنلاقي هنا فيه بروز هذا البروز اسمه ال medial
+
+272
+00:21:32,370 --> 00:21:35,250
+malleolus وفيه كمان بروز للفيبيولا اسمها ال
+
+273
+00:21:35,250 --> 00:21:39,970
+lateral malleolus أما الفيبيولا فهي بيروح عن ال
+
+274
+00:21:39,970 --> 00:21:42,890
+lateral bone و long cylindrical head هذه non
+
+275
+00:21:42,890 --> 00:21:46,430
+-weight bearing bone مابتحملش أي weight bearing
+
+276
+00:21:46,430 --> 00:21:50,430
+عشان هي لو انكسرت مابتأثر كتير على المشي إلا من
+
+277
+00:21:50,430 --> 00:21:56,000
+خلال الال ankle foots طبعا ال ankle and foot في
+
+278
+00:21:56,000 --> 00:22:01,380
+عندنا عدد من العظام تقريبا في عندنا اربعتاشر ترث
+
+279
+00:22:01,380 --> 00:22:04,920
+البون هي ال calcaneus و التاليوس و ال navicular و
+
+280
+00:22:04,920 --> 00:22:08,080
+الكيوبيد و الكيوبايد و عندنا ال lateral cuneiform
+
+281
+00:22:08,080 --> 00:22:11,240
+و ال intermediate cuneiform و ال medial cuneiform
+
+282
+00:22:11,240 --> 00:22:15,220
+كلهم هدولة تكونوا مواضحين على ال skeleton بهذا
+
+283
+00:22:15,220 --> 00:22:21,370
+الشكل زي ما احنا شايفينطبعا ال metatarsals فى
+
+284
+00:22:21,370 --> 00:22:25,210
+عندنا ten metatarsals بقول خمسة على اليمين و خمسة
+
+285
+00:22:25,210 --> 00:22:30,010
+على اليسار و فى عندنا الفلانجز زى ما قولنا فى
+
+286
+00:22:30,010 --> 00:22:38,430
+عندنا ال four lateral toys فىهم تلات لانجز اللى هى
+
+287
+00:22:38,430 --> 00:22:42,050
+ال proximal, intermediate and distal اما ال thumb
+
+288
+00:22:42,050 --> 00:22:48,150
+فهو only two flanges بالظبط نفس تركيبة ال upper ال
+
+289
+00:22:48,150 --> 00:22:48,410
+hand
+
+290
+00:22:51,900 --> 00:22:55,040
+طبعا في حاجة اسمها arches of the foot لو لاحظنا
+
+291
+00:22:55,040 --> 00:22:58,480
+أنه كلنا طلعنا على أسفل القدم عندنا فبنلاقي فيه
+
+292
+00:22:58,480 --> 00:23:02,840
+arch في عندنا medial arch موجود على الناحية اليمين
+
+293
+00:23:02,840 --> 00:23:05,360
+هو أنا ال skeleton اللي عندي هنا مشوّه شوية بس أنا
+
+294
+00:23:05,360 --> 00:23:09,320
+بقدر أو أوضح هنا أنه في هنا ال medial arch وفي هنا
+
+295
+00:23:09,320 --> 00:23:13,400
+slightly lateral أصغر منه شوية lateral arch ماعرفش
+
+296
+00:23:13,400 --> 00:23:18,310
+إذا واضح بالصورة أو لأ وفي عندنا كمانفي transverse
+
+297
+00:23:18,310 --> 00:23:22,050
+arch هدول إيش وظيفتهم ال arches هدول يعملوا عملية
+
+298
+00:23:22,050 --> 00:23:25,930
+shock absorption عشان العضام الرجل مش كل منطوب
+
+299
+00:23:25,930 --> 00:23:29,330
+بالأرض يكون فيه تاخد ضربة هذه بتعمل shock
+
+300
+00:23:29,330 --> 00:23:35,630
+absorption يعني تبص الصدمات على العضام ال foot
+
+301
+00:23:35,630 --> 00:23:38,430
+طبعا في ناس عندهم flat foot عندنا هنقول من إيش
+
+302
+00:23:38,430 --> 00:23:42,640
+هدول ممكن يعنيطبعا ال soul of the foot does not
+
+303
+00:23:42,640 --> 00:23:47,100
+rest flat on the ground في عندنا .. ليش؟ ليش
+
+304
+00:23:47,100 --> 00:23:49,880
+بيكونش flat؟ بيكون في عندنا عرش support the weight
+
+305
+00:23:49,880 --> 00:23:53,540
+of the body طبعا بيكون في عندنا blood vessels
+
+306
+00:23:53,540 --> 00:23:57,000
+موجودة في ال soul of the foot لو كانت الأجر بتنزل
+
+307
+00:23:57,000 --> 00:24:01,540
+flat على الأرض فبصير في عندنا squeezing أو ضغط على
+
+308
+00:24:01,540 --> 00:24:05,200
+ال vessels هذه فهذه ممكن أنها تقلل الدورة الدموية
+
+309
+00:24:05,200 --> 00:24:08,480
+عشان هيك بتكون مقوسة عشان لما احنا نزل رجلنا على
+
+310
+00:24:08,480 --> 00:24:13,690
+الأرضما تنزلش flat تضغط الأوعية الدموية
+
+311
+00:24:18,340 --> 00:24:22,660
+طبعا على ال powerpoint موضحة ال arches في عندنا
+
+312
+00:24:22,660 --> 00:24:26,520
+بعض المشاكل اللي بتصيب ال lower limb أو ال foot
+
+313
+00:24:26,520 --> 00:24:30,400
+بالذات في حاجة اسمها halox valgus تلاحظ ان بعض
+
+314
+00:24:30,400 --> 00:24:37,480
+الناس ممكن يصير في خلل في تركيبة ال first toys toy
+
+315
+00:24:37,480 --> 00:24:42,560
+اللي هو ال halox احنا بنسميه بيصير فيه deviationof
+
+316
+00:24:42,560 --> 00:24:45,780
+the greater to add the metatarsal phalangeal joint
+
+317
+00:24:45,780 --> 00:24:50,720
+طبعا ال incidence أكتر في ال women من ال men بنتج
+
+318
+00:24:50,720 --> 00:24:53,480
+عن ال bad lifted foods طبعا في ال food أنتوا
+
+319
+00:24:53,480 --> 00:24:56,400
+عارفينها اللي هي ال .. ال .. ال .. البوز الرفيع
+
+320
+00:24:56,400 --> 00:25:01,120
+هذه فبتلاقي الأصابع بتكون كده يعني مضغوطة جواها
+
+321
+00:25:01,120 --> 00:25:05,350
+فعلى ال long term ممكن تعملنا مشاكلأو ممكن يكون في
+
+322
+00:25:05,350 --> 00:25:10,770
+عندنا short لل first metatarsal بتأدي لهذه المشكلة
+
+323
+00:25:10,770 --> 00:25:13,850
+طبعا إذا صارت ال deformity هادي موجودة فمعناها هي
+
+324
+00:25:13,850 --> 00:25:18,530
+أنها ممكن أنها تتطور تطور نتيجة pull of the
+
+325
+00:25:18,530 --> 00:25:23,180
+muscles around the halluxطبعا في ال halox rigidus
+
+326
+00:25:23,180 --> 00:25:26,280
+ممكن يصير فيه calcification على ال
+
+327
+00:25:26,280 --> 00:25:29,220
+metatarsophalangeal joints أو osteoarthritic
+
+328
+00:25:29,220 --> 00:25:35,580
+exchanges فممكن هذه تعملي painful and stiff toy،
+
+329
+00:25:35,580 --> 00:25:39,610
+big toyفي ال bisplanas الناس اللي بنسموهم ال flat
+
+330
+00:25:39,610 --> 00:25:44,010
+foots هدولة أجرهم بتكون ال arches كلها ممسوحة
+
+331
+00:25:44,010 --> 00:25:49,550
+فبتنزل رجلهم على الأرض مباشرة، هذا عبارة عن
+
+332
+00:25:49,550 --> 00:25:53,350
+depression أو collapse لل longitudinal arch،
+
+333
+00:25:53,350 --> 00:25:58,310
+result ال four foot كلها بتكون laterally بتروحعلى
+
+334
+00:25:58,310 --> 00:26:03,190
+الناحية ال laterally ال head of the talus no
+
+335
+00:26:03,190 --> 00:26:07,190
+longer supported the cause of a flat foot both
+
+336
+00:26:07,190 --> 00:26:11,110
+congenital or acquired congenital انه بنولد لإن هو
+
+337
+00:26:11,110 --> 00:26:14,730
+من عائلة عندهم flat foot او acquired لإن في عندنا
+
+338
+00:26:14,940 --> 00:26:19,180
+ال .. الفوض ال .. ال .. الشوذ اللي بتستخدم دائما
+
+339
+00:26:19,180 --> 00:26:23,180
+ممكن تكون منذ الطفولة سيئة فبتأثر هذا و أعطيكم
+
+340
+00:26:23,180 --> 00:26:25,800
+العافية و أرجو أن أكون أوشظت في مجال ال
+
+341
+00:26:25,800 --> 00:26:28,900
+appendicular system و المشاكل اللي ممكن تصيب الفوض
+
+342
+00:26:28,900 --> 00:26:30,380
+السلام عليكم و رحمة الله
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY.srt
new file mode 100644
index 0000000000000000000000000000000000000000..dea370c0c6efbb201f74997d78c0e38430644430
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY.srt
@@ -0,0 +1,1454 @@
+1
+00:00:04,940 --> 00:00:08,860
+بسم الله الرحمن الرحيم والصلاة والسلام على سيدنا
+
+2
+00:00:08,860 --> 00:00:12,600
+محمد سيد المرسلين، اليوم محاضرتنا استكمال لل
+
+3
+00:00:12,600 --> 00:00:17,120
+skeletal system، في جزء مهم في الـ skeletal system،
+
+4
+00:00:17,120 --> 00:00:22,120
+لازم نتعرف عليه، هو الـ joints أو الـ articulations
+
+5
+00:00:22,610 --> 00:00:27,030
+طبعًا وظيفة الـ joints هي أنها تربط بين two adjacent
+
+6
+00:00:27,030 --> 00:00:31,250
+bones، و تعريف الـ joints يعني اللي هو الـ wrap between two
+
+7
+00:00:31,250 --> 00:00:37,070
+adjacent bones، يعني عظمتين يكونوا بشكل مفصل عن
+
+8
+00:00:37,070 --> 00:00:42,010
+طريق التلاحم، وطبعًا التلاحم هذا بيكون حسب شكل
+
+9
+00:00:42,010 --> 00:00:46,450
+المفصل، بتعطينا نوع الحركة، يبقى أول حاجة الـ joints
+
+10
+00:00:46,450 --> 00:00:49,350
+هي اللي بتربط العظام مع بعضها وبتخلينا احنا
+
+11
+00:00:49,350 --> 00:00:53,450
+واقفين هيك، احنا لو ما كانش فيه عندنا joints فبيكون
+
+12
+00:00:53,450 --> 00:00:56,750
+احنا بنشتغل زي الـ robot، ما فيش إمكانية إن احنا لا
+
+13
+00:00:56,750 --> 00:00:59,970
+نتحرك أيدينا ولا نتحرك أرجلنا ولا نتحرك، حركة
+
+14
+00:00:59,970 --> 00:01:06,460
+بصورة خلينا نقول متصلبة، فالـ ... يبقى الـ articulations
+
+15
+00:01:06,460 --> 00:01:14,120
+بتساعدني على الحركة، وكمان بتساعد على النمو، كيف؟ لو
+
+16
+00:01:14,120 --> 00:01:18,600
+احنا ولدنا بنفس الحجم هذا، فكان طبعًا مستحيل عملية
+
+17
+00:01:18,600 --> 00:01:21,040
+الحمل والولادة هذه تصير، فعشان هيك احنا ولدنا
+
+18
+00:01:21,040 --> 00:01:25,880
+باحجام صغيرة، وكان لازم عملية النمو الطبيعي هذه تكون
+
+19
+00:01:25,880 --> 00:01:31,600
+فعشان هيك كان في نهاية العظمة قبل ما يبدأ المفصل
+
+20
+00:01:31,600 --> 00:01:35,280
+في عندنا في الـ epiphysis في عندنا الـ epiphysial
+
+21
+00:01:35,280 --> 00:01:43,290
+growth، فكان فيه عملية نمو للعظام، كمان بتساعدنا على
+
+22
+00:01:43,290 --> 00:01:51,230
+التغيير شكل العظام أثناء النمو، وكمان بتساعد على
+
+23
+00:01:51,230 --> 00:01:55,430
+الـ movement من خلال الـ articulations، من خلال
+
+24
+00:01:55,430 --> 00:01:58,990
+العضلات اللي بتكون حوالي المفصل، طيب
+
+25
+00:02:03,070 --> 00:02:06,350
+كيف احنا سمينا هذه المفاصل، أو كيف العلماء سموا
+
+26
+00:02:06,350 --> 00:02:14,410
+هذه المفاصل؟ طبعًا الاسم دائمًا derived من الـ
+
+27
+00:02:14,410 --> 00:02:19,230
+articulating bones، يعني الـ tibia مع الـ femur
+
+28
+00:02:19,230 --> 00:02:24,570
+هتعطيني الـ knee، الـ humerus and ulna مع الـ radius
+
+29
+00:02:24,570 --> 00:02:31,090
+هتعطيني الـ elbow، وهكذا، اللي قده حسب ترتيبه هتكون
+
+30
+00:02:31,090 --> 00:02:35,630
+أسماء الـ articulations، حتى وكمان أنواعها اللي
+
+31
+00:02:35,630 --> 00:02:40,570
+بتعتمد على shape of the articular surfaces، طبعًا
+
+32
+00:02:40,570 --> 00:02:41,910
+تقسيمتها
+
+33
+00:02:44,110 --> 00:02:51,330
+بتنقسم بصراحة حسب الحركة وحسب شكل المفصل، نروح للـ
+
+34
+00:02:51,330 --> 00:02:57,550
+fibrous joints، هي عبارة عن dense connective tissue
+
+35
+00:02:57,550 --> 00:03:04,650
+بتجمع الـ bones together، الـ bones بيكونوا متلاصقة جدًا،
+
+36
+00:03:04,650 --> 00:03:08,090
+يعني بيكون ما فيش فراغات بين الـ bones، يعني ما فيش real
+
+37
+00:03:08,090 --> 00:03:13,270
+articulation، الحقيقة two bones adjacent مرتبطين مع
+
+38
+00:03:13,270 --> 00:03:18,070
+بعضهم، لكن ما فيش كتير منها movement، أما الـ
+
+39
+00:03:18,070 --> 00:03:22,750
+cartilaginous، فهي عبارة عن  يالين كارتيلاج وفيبرو
+
+40
+00:03:22,750 --> 00:03:26,250
+كارتيلاج، connected bones، في هذا الشكل، يعني خلينا
+
+41
+00:03:26,250 --> 00:03:29,430
+نقول الـ fibers، نكون في عظمتين جنب بعض، الحركة
+
+42
+00:03:29,430 --> 00:03:33,630
+فيهم مش ضرورية، لكن لازم يكون في خلينا نقول
+
+43
+00:03:33,630 --> 00:03:38,110
+الالتصاق تبع العظام أو الـ stability تبع العظمتين
+
+44
+00:03:38,110 --> 00:03:43,160
+مع بعض، الكارتيلاج لأ، بتختلف شوية، إن في عندنا
+
+45
+00:03:43,160 --> 00:03:47,360
+التصاق للعظام، لكن مش مباشر، في عندنا cartilage أو
+
+46
+00:03:47,360 --> 00:03:53,660
+fibrocartilage أو أو disc، أو إذا نقول الـ disc في
+
+47
+00:03:53,660 --> 00:03:56,180
+عندنا الـ annulus fibrosus، وفي عندنا الـ nucleus اللي
+
+48
+00:03:56,180 --> 00:04:00,940
+هي بتساعد على الـ fabrication للمفصل وبتساعد
+
+49
+00:04:00,940 --> 00:04:04,500
+على الحركة البسيطة، أما الـ synovial joints، وهذه الـ
+
+50
+00:04:04,500 --> 00:04:06,900
+joints الكبيرة اللي موجودة، المفاصل الكبيرة زي الـ
+
+51
+00:04:06,900 --> 00:04:11,220
+elbow والـ hip، هدول بيكون أول حاجة الـ complex لأن
+
+52
+00:04:11,220 --> 00:04:13,520
+تركيبها، والـ articular shared surface، والـ synovial
+
+53
+00:04:13,520 --> 00:04:17,060
+fluid، والـ ligaments جوا، والـ ligaments برا، وبتكون
+
+54
+00:04:17,060 --> 00:04:20,680
+محاطة بالـ synovial membrane، وهكذا، هذه هي المفاصل
+
+55
+00:04:20,680 --> 00:04:24,740
+اللي احنا بتساعد على الحركة الكبيرة اللي احنا
+
+56
+00:04:24,740 --> 00:04:28,580
+بنتحركها سواء في الـ ambulation أو الـ locomotion أو
+
+57
+00:04:28,580 --> 00:04:34,660
+في المصول للأشياء، الأنواع لو... لو إجينا اتكلمنا
+
+58
+00:04:34,660 --> 00:04:39,560
+على الـ... يعني صنفناها according to the movement
+
+59
+00:04:39,560 --> 00:04:42,960
+فبنلاقي إنه إلها تصنيف ثاني، هي الـ syn
+
+60
+00:04:42,960 --> 00:04:47,120
+arthrosis، الـ immovable bones، والـ amphiarthrosis، الـ
+
+61
+00:04:47,120 --> 00:04:50,300
+slightly movable joint، والـ diarthrosis اللي هي زي
+
+62
+00:04:50,300 --> 00:04:54,800
+الـ synovial joints، فهي freely movable joints
+
+63
+00:04:57,100 --> 00:05:00,600
+ناخد أنواع أو أشكال الـ fibrous joints، هنلاقيها
+
+64
+00:05:00,600 --> 00:05:04,940
+three types، بيسموها الـ syndesmosis، والسوتشر،
+
+65
+00:05:04,940 --> 00:05:09,680
+والgomphosis، طيب إيش الفرق ما بينهم؟ الـ syndesmosis
+
+66
+00:05:09,680 --> 00:05:14,080
+فهو عبارة عن sheet بين two bones، زي ما احنا
+
+67
+00:05:14,080 --> 00:05:20,020
+شايفين في الصورة اللي على اليمين هنا أو على يسار
+
+68
+00:05:20,020 --> 00:05:25,260
+الصورة، إن فيه إن الـ tibia and fibula موجود في
+
+69
+00:05:25,260 --> 00:05:28,600
+بينهم كده غشاء، الغشاء هذا رابط هدول العظمتين عشان
+
+70
+00:05:28,600 --> 00:05:32,400
+يكونوا أكثر stability، هما العظمتين مرتبطين من تحت
+
+71
+00:05:32,400 --> 00:05:37,380
+المفصل ومن فوق المفصل، المفصلين هدول مش متحركين،
+
+72
+00:05:37,380 --> 00:05:43,010
+تمام؟  فـ sheet or bundle of fibrous tissue connects
+
+73
+00:05:43,010 --> 00:05:46,570
+the bones هنا، أما في الـ sutures، يعني slightly movable
+
+74
+00:05:46,570 --> 00:05:49,910
+joints، ما بتتحركش كتير، يعني هي بتسمح بالحركة
+
+75
+00:05:49,910 --> 00:05:55,210
+القليلة جدًا، ودايمًا يعني أكثر مثال نضرب عليه اللي
+
+76
+00:05:55,210 --> 00:05:59,810
+هو الـ joints بين tibia و fibula، الـ suture
+
+77
+00:05:59,810 --> 00:06:04,350
+طبعًا احنا كلنا بنعرف إن الـ skull مجموعة من الـ
+
+78
+00:06:04,350 --> 00:06:07,590
+bones، زي ما اتكلمنا فيه، عينة frontal و parietal و
+
+79
+00:06:07,590 --> 00:06:11,150
+temporal و occipital، هدول بيشكّلوا الـ skull، ولا
+
+80
+00:06:11,150 --> 00:06:15,090
+فيه في الأول في بينهم فيه foramen، تمام؟ حالتها لما
+
+81
+00:06:15,090 --> 00:06:18,790
+بيتحم هذا الـ foramen بيصير على شكل suture زي اللي
+
+82
+00:06:18,790 --> 00:06:23,290
+احنا شايفينها بالرسم، كأنه مخيطة خياطة، هذه خياطة
+
+83
+00:06:23,290 --> 00:06:27,560
+ربانية، هي تربط، يبقى الـ suture تربط بين الـ
+
+84
+00:06:27,560 --> 00:06:31,660
+flat bones، وهي synarthrosis، synarthrosis يعني إنها
+
+85
+00:06:31,660 --> 00:06:35,640
+immovable joints، thin layer of connective tissue
+
+86
+00:06:35,640 --> 00:06:38,600
+connects the bones، وزي ما احنا شايفينه، أما
+
+87
+00:06:38,600 --> 00:06:46,200
+الـ gomphosis، هي عبارة عن جذر تبع الـ teeth، هي cone
+
+88
+00:06:46,200 --> 00:06:50,940
+shaped bone process in a socket، يعني في جيب شكل
+
+89
+00:06:50,940 --> 00:06:56,320
+مخروطي الشكل، مزروعة فين؟ مزروعة في
+
+90
+00:06:56,320 --> 00:07:01,200
+مكان معين، في جيب معين، زي الـ tooth in the jawbone،
+
+91
+00:07:01,200 --> 00:07:04,920
+طبعًا احنا بنعرف إن كل سن فيه جذر، الجذر هذا موجود
+
+92
+00:07:04,920 --> 00:07:08,780
+في اللثة، وهذه synarthrosis، يعني تخيّل إن لو إنها
+
+93
+00:07:08,780 --> 00:07:12,200
+movable، كان احنا عمرنا ما عرفنا نمضغ أو ناكل، يبقى
+
+94
+00:07:12,200 --> 00:07:16,900
+الأسنان مثبتة، واحنا بنرى لو هذا المفصل صار يعني
+
+95
+00:07:16,900 --> 00:07:22,360
+متراخ شوية، بيعني إن القلم الجذري بيقدر يخلع هذا السن،
+
+96
+00:07:22,360 --> 00:07:28,100
+فهي synarthrosis، no movement، زي هذا الشكل
+
+97
+00:07:28,100 --> 00:07:34,080
+اللي احنا شايفينه، جذر السن، أما الـ cartilaginous فهي
+
+98
+00:07:34,080 --> 00:07:39,500
+synchondrosis، مش متحركة، زي الـ... الـ... الـ... الـ...
+
+99
+00:07:39,500 --> 00:07:42,800
+الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ...
+
+100
+00:07:42,800 --> 00:07:43,740
+الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ...
+
+101
+00:07:43,740 --> 00:07:43,780
+الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ...
+
+102
+00:07:43,780 --> 00:07:45,800
+الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ...
+
+103
+00:07:45,800 --> 00:07:45,860
+الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ...
+
+104
+00:07:45,860 --> 00:07:46,700
+الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ...
+
+105
+00:07:46,700 --> 00:07:46,760
+الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ...
+
+106
+00:07:46,760 --> 00:07:46,840
+الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ... الـ...
+
+107
+00:07:46,840 --> 00:07:54,010
+الـ... الـ... الـ... يبقى synchondrosis، bones of
+
+108
+00:07:54,010 --> 00:07:56,870
+hyaline cartilage، joined to bone، يعني احنا
+
+109
+00:07:56,870 --> 00:08:00,830
+بنلاقي كل rib في نهايتها زي ما احنا شايفين في عندنا
+
+110
+00:08:00,830 --> 00:08:03,750
+cartilage، بنسميه costal cartilage، بيعمل
+
+111
+00:08:03,750 --> 00:08:06,610
+attachments مع الـ sternum
+
+112
+00:08:07,990 --> 00:08:11,750
+في الـ epiphysis للـ ribs، طبعًا هذا الـ ribs اللي بيسمح
+
+113
+00:08:11,750 --> 00:08:16,290
+بعملية النمو، عشان إن كل ما بنكبر كل ما بيكبر، هذا
+
+114
+00:08:16,290 --> 00:08:22,130
+بيصير ossification، وبيساعد على طول العظام كمان،
+
+115
+00:08:22,130 --> 00:08:29,090
+هدول synarthrosis، يعني غير متحركة أو immovable
+
+116
+00:08:31,330 --> 00:08:34,730
+أما الـ symphysis، هذا النوع الثاني، فهي band of
+
+117
+00:08:34,730 --> 00:08:37,830
+fibrocartilage between the bones، شفناها في
+
+118
+00:08:37,830 --> 00:08:41,130
+المحاضرة اللي فاتت، في الـ pubic symphysis اللي
+
+119
+00:08:41,130 --> 00:08:47,610
+بيعمل articulation to pubic bones، في الـ pelvic bones، joints
+
+120
+00:08:47,610 --> 00:08:50,710
+between bodies of adjacent vertebrae، قلنا each
+
+121
+00:08:50,710 --> 00:08:55,210
+vertebra بين two adjacent vertebrae، في عندنا الـ
+
+122
+00:08:55,210 --> 00:08:59,030
+intervertebral disc، موضّح بالرسم، وهو ده الـ
+
+123
+00:08:59,030 --> 00:09:03,250
+amphiarthrosis، means إنه slightly movable joints
+
+124
+00:09:03,250 --> 00:09:04,830
+عشان تسمح بالحركة
+
+125
+00:09:07,150 --> 00:09:10,790
+أما الـ synovial، فهو الـ most complicated joints
+
+126
+00:09:10,790 --> 00:09:16,710
+هي منتشرة على معظم مفاصل الجسم اللي فيها real
+
+127
+00:09:16,710 --> 00:09:21,190
+movement، a basic feature، أول حاجة إنها بتحتوي على
+
+128
+00:09:21,190 --> 00:09:27,670
+articular capsule، في جيب كده أو غشاء محيط بالمفصل
+
+129
+00:09:28,410 --> 00:09:33,450
+أيضًا فيها synovial cavity، بتبقى full of synovial
+
+130
+00:09:33,450 --> 00:09:37,090
+fluid، عشان يساعد على تغذية الـ cartilage ويساعد
+
+131
+00:09:37,090 --> 00:09:40,510
+كمان على الـ movement ويعمل نوع من الـ lubricant
+
+132
+00:09:40,510 --> 00:09:44,550
+inside the joint، فيعني الـ articular cartilage
+
+133
+00:09:44,550 --> 00:09:48,830
+اللي هو covering الـ heads أو خلينا نقول الـ
+
+134
+00:09:48,830 --> 00:09:53,550
+epiphysis، الـ contact bones مع الـ other bones، لازم
+
+135
+00:09:53,550 --> 00:09:58,530
+تكون مادة ناعمة جدًا مثل الـ cartilage، و أي خشونة في هذا
+
+136
+00:09:58,530 --> 00:10:01,990
+الـ... في هذا الـ cartilage ممكن تؤدي
+
+137
+00:10:01,990 --> 00:10:05,990
+إلى... إلى pain، و ligaments، ليش؟ الـ ligaments هي
+
+138
+00:10:05,990 --> 00:10:10,470
+الأربطة اللي بتربط هدول العظمتين مع بعض حتى تمنع
+
+139
+00:10:10,470 --> 00:10:14,670
+الازدياد المفصل، وكمان nerves و blood vessels، الـ
+
+140
+00:10:14,670 --> 00:10:20,270
+nerves عشان تعطيني sensory order، كمان بيكون الـ... الـ
+
+141
+00:10:20,270 --> 00:10:26,170
+bones احنا حكينا innervated، أما الـ cartilage لأ، و
+
+142
+00:10:26,170 --> 00:10:28,590
+الـ blood vessels، قلنا الـ cartilage is not
+
+143
+00:10:28,590 --> 00:10:29,890
+vascularized
+
+144
+00:10:33,590 --> 00:10:39,210
+نروح للـ Anatomy of the synovial joint، الـ Accessory
+
+145
+00:10:39,210 --> 00:10:42,930
+Structures فيها إن حاجة اسمها الـ bursae، الـ bursae
+
+146
+00:10:42,930 --> 00:10:49,010
+هي عبارة عن sac، جيبة فيها synovial fluid، هذه
+
+147
+00:10:49,010 --> 00:10:52,530
+بتكون موجودة في أماكن الاحتكاك عشان تمنع
+
+148
+00:10:52,530 --> 00:10:55,090
+الاحتكاك أثناء الحركة، يبقى هي
+
+149
+00:11:03,670 --> 00:11:07,150
+أما في كمان نوع ثاني من المخدات، خلينا نسميهم مخدات
+
+150
+00:11:07,150 --> 00:11:10,870
+احنا، اللي هي الـ fat pads، دائمًا distributed along
+
+151
+00:11:10,870 --> 00:11:14,170
+the periphery of the synovial joint، في جوانب الـ
+
+152
+00:11:14,170 --> 00:11:19,280
+periphery joint، act as padding material، and it
+
+153
+00:11:19,280 --> 00:11:23,320
+provides some protection، بتساعد على حماية هذا
+
+154
+00:11:23,320 --> 00:11:30,520
+المفصل، دائمًا بتملأ الفراغات بين العظام عشان تساعد
+
+155
+00:11:30,520 --> 00:11:34,720
+على الـ stability وبتحسّن من الـ congruence of the
+
+156
+00:11:34,720 --> 00:11:39,280
+joint، إيش الـ congruence؟ اللي هو تطابق الـ joints
+
+157
+00:11:39,280 --> 00:11:44,960
+نفسه؟ أما الـ tendon sheaths فهي نهايات الـ muscles اللي
+
+158
+00:11:44,960 --> 00:11:47,940
+بتعمل attachment مع الـ bone، دائمًا بالـ
+
+159
+00:11:47,940 --> 00:11:54,180
+stabilization of the joint، وهذا خلينا نقول شكل الـ
+
+160
+00:11:54,180 --> 00:11:58,680
+knee joint هو تقريبًا الـ most complicated joint in
+
+161
+00:11:58,680 --> 00:12:05,050
+the body، لأنه فيه كتير من الـ... خلينا نقول الأجزاء
+
+162
+00:12:05,050 --> 00:12:10,370
+زي الـ articular surfaces، زي الـ patella، في عندنا
+
+163
+00:12:10,370 --> 00:12:16,250
+الـ... الـ intervertebral menisci، في عندنا الـ
+
+164
+00:12:16,250 --> 00:12:18,490
+ligaments، في عندنا الـ bursae، الـ ligaments، اللي
+
+165
+00:12:18,490 --> 00:12:23,550
+هنشرحهم واحد واحد، فهي الـ bursa هي هذه عشان تعمل
+
+166
+00:12:23,550 --> 00:12:27,650
+passages للتاندون، زي التاندون بتاع patella، بيكون في عندنا
+
+167
+00:12:27,650 --> 00:12:34,970
+الـ bursa هي أساسًا إنها تساعد في الحركة، هذا هنشرحه
+
+168
+00:12:34,970 --> 00:12:40,240
+عندما نصل للمفصل الرضفي، وهذا شكل ثاني للـ tendon
+
+169
+00:12:40,240 --> 00:12:43,820
+sheaths، اللي موجودة في الـ wrist، هذه الـ sheaths
+
+170
+00:12:43,820 --> 00:12:49,320
+بتساعد على إن تخلي الـ tendons، هذه الأوتار هذه في
+
+171
+00:12:49,320 --> 00:12:52,400
+أماكنها، لو كان افترضنا إن فيه مشكلة في واحد من
+
+172
+00:12:52,400 --> 00:12:56,620
+هذه الـ sheaths هذه، هذا ممكن يؤدي لإنه الـ tendon
+
+173
+00:12:56,620 --> 00:13:00,460
+ما يكونش stable، ويعلق، يعني مثل الـ trigger fingers،
+
+174
+00:13:00,460 --> 00:13:03,340
+
+223
+00:17:14,290 --> 00:17:19,350
+Socket اللي هو من المفاصل الـ freely movable
+
+224
+00:17:19,350 --> 00:17:24,910
+joints وفيها movement in the three planes زي الـ
+
+225
+00:17:24,910 --> 00:17:32,010
+shoulder and hip joint طيب نشوف  أن على الشكل هنا
+
+226
+00:17:32,010 --> 00:17:36,290
+الـ hip مهم في عين الـ acetabulum وفي عين الـ head of
+
+227
+00:17:36,290 --> 00:17:49,150
+femur عاملين زي كأنها كرة جوات يعني حاوية وفي
+
+228
+00:17:49,150 --> 00:17:54,210
+عندنا النقطة
+
+229
+00:17:54,210 --> 00:17:58,360
+الثانية زي ما احنا شايفين الـ Condyloid Joint بهذا
+
+230
+00:17:58,360 --> 00:18:01,540
+الشكل الـ Condyloid برضه بيعطينا movement بس in
+
+231
+00:18:01,540 --> 00:18:05,080
+two planes أو by axial plane زي الـ
+
+232
+00:18:05,080 --> 00:18:07,960
+Metacarpophalangeal Joints اللي وضحناها قبل شوية
+
+233
+00:18:07,960 --> 00:18:13,500
+الـ Condyloid بين الـ Metacarpophalangeal Joints أما
+
+234
+00:18:13,500 --> 00:18:20,330
+الـ gliding joint فهي عبارة عن movement of gliding
+
+235
+00:18:20,330 --> 00:18:25,890
+between the tarsal and carpal bones إذا بتذكروا في
+
+236
+00:18:25,890 --> 00:18:29,910
+الـinternet بيقولنا في عندنا two rows of carpal bones الـ
+
+237
+00:18:29,910 --> 00:18:33,030
+proximal row و الـ distal row الـ movement ما بينهم
+
+238
+00:18:33,030 --> 00:18:37,690
+بتكون فقط gliding بس إزاحة عملية إزاحة أما الـ
+
+239
+00:18:37,690 --> 00:18:44,750
+hinge joint فهي عبارة عن الـ elbow and knee وكمان
+
+240
+00:18:44,750 --> 00:18:48,450
+between the phalanges أو الـ interphalangeal joints
+
+241
+00:18:50,030 --> 00:18:53,350
+طبعا الشيء اللي بيحدد الحركة قلنا شكل المفصل
+
+242
+00:18:53,350 --> 00:18:56,610
+تخيلنا شكل المفصل حسب الصورة بنلاقي أن شكل المفصل
+
+243
+00:18:56,610 --> 00:19:01,550
+ما بيسمح إلا بحركة بهذا الاتجاه أما الـ pivot فهو
+
+244
+00:19:01,550 --> 00:19:06,290
+عبارة عن حركة دوران حوالي محور الحركة هذه إذا ما
+
+245
+00:19:06,290 --> 00:19:09,670
+اتذكر لما اتكلمنا عن الـ Atlas و الـ Axis اللي هما
+
+246
+00:19:09,670 --> 00:19:14,090
+الـ first and second cervical vertebrae فقلنا الـ
+
+247
+00:19:14,090 --> 00:19:18,470
+Axis فيه إلها الـ Odontoid process  هذي process
+
+248
+00:19:18,470 --> 00:19:23,910
+موجودة في الفتحة أو في الـ foramen في الـ Axis لأن هما
+
+249
+00:19:23,910 --> 00:19:28,290
+كانت أشكالهم كانت مختلفة إذا بتذكروا وإنها بتسمح
+
+250
+00:19:28,290 --> 00:19:35,980
+بحركة الـ rotation هذه بتشكل pivot joint أما الـ
+
+251
+00:19:35,980 --> 00:19:41,040
+الجنف هو عامل زي حدوث الفرس أو زي سرج الحصان تمام؟
+
+252
+00:19:41,040 --> 00:19:48,400
+هذا بيسمح بحركة برضه بيه أكثر من axis احنا بنلاحظ
+
+253
+00:19:48,400 --> 00:19:51,840
+أن الـ thumb flexion, extension, abduction, adduction
+
+254
+00:19:51,840 --> 00:19:55,320
+وحاجة بنسميها opposition  opposition يعني حركة
+
+255
+00:19:55,320 --> 00:19:58,460
+دوران اللي احنا حلقة التسبيح هذه يا جماعة إذا
+
+256
+00:19:58,460 --> 00:20:02,970
+انتوا يعني بتسبحوا الحركة التسبح هي عبارة عن
+
+257
+00:20:02,970 --> 00:20:08,670
+opposition of the metacarpophalangeal joint of the
+
+258
+00:20:08,670 --> 00:20:09,470
+thumb
+
+259
+00:20:15,620 --> 00:20:20,480
+هنا إذا احنا شايفين في الـ slide هذه الحركة الـ
+
+260
+00:20:20,480 --> 00:20:25,020
+planar joints between the navicular and the second
+
+261
+000:20:25,020 --> 00:20:29,840
+and third cuneiform of the tarsal bones  نجد أن
+
+262
+00:20:29,840 --> 00:20:33,940
+الرسم أنه فيه مفاصل لكن الحركة فيهم بسيطة بتصير
+
+263
+00:20:33,940 --> 00:20:37,040
+أثناء الـ weight bearing و المشي
+
+264
+00:20:39,400 --> 00:20:43,580
+هيتكلمنا عن الـ Stability فاحنا بن .. يعني الرسم
+
+265
+00:20:43,580 --> 00:20:46,800
+التوضيحي اللي موجود واحنا بنعرف قاعدة أساسية في
+
+266
+00:20:46,800 --> 00:20:49,040
+الـ Biomechanics إذا في حدا مننا درس الـ
+
+267
+00:20:49,040 --> 00:20:54,040
+Biomechanics أنه كل ما كان الجسم mobile أكثر كل ما
+
+268
+00:20:54,040 --> 00:20:58,540
+قلت الـ Stability  بمعنى أنه في تناسب عكسي بين الـ
+
+269
+00:20:58,540 --> 00:21:04,380
+mobility و الـ stability كل ما كان الجسم
+
+270
+00:21:05,590 --> 00:21:09,730
+أقل حركة أو حركته أقل فكل ما كانت stability تبعته
+
+271
+00:21:09,730 --> 00:21:13,810
+أعلى فلو تدرجنا بالمفاصل بنلاقي المفاصل في جسم
+
+272
+00:21:13,810 --> 00:21:18,130
+الإنسان بتبدأ من الأقل stability وأكثرهم
+
+273
+00:21:18,130 --> 00:21:22,470
+mobility هو الـ shoulder joint لأن بنعمل 180 flexion
+
+274
+00:21:22,470 --> 00:21:28,550
+و 180 abduction وبناخد حركة الـ rotation بتوصل لـ 90
+
+275
+00:21:30,140 --> 00:21:35,320
+فهو ليس stable  وكمان شكل المفصل هو بيقلل يعني بي
+
+276
+00:21:35,320 --> 00:21:38,320
+.. يعني شكل المفصل نفسه أنه مافيش فيه congruency
+
+277
+00:21:38,320 --> 00:21:41,940
+كثير مافيش فيه تطابق كثير وبيحتاج لبادل كثير في
+
+278
+00:21:41,940 --> 00:21:47,280
+حاجة اسمها labrum حوالين الـ glenoid cavity في الكتف
+
+279
+00:21:47,280 --> 00:21:51,100
+بتساعد على الـ congruence فهو أقل stable كمان الـ
+
+280
+00:21:51,100 --> 00:21:55,260
+hip هو يعني الـ stability اللي بيستمدها من كمية الـ
+
+281
+00:21:55,260 --> 00:21:59,600
+ligaments اللي موجودة عليه لكن هو كمان less stable
+
+282
+00:21:59,600 --> 00:22:06,320
+جون القلبه بيتدرج هو بيروح ناحية الـ stability أكثر
+
+283
+00:22:06,320 --> 00:22:10,700
+وقلنا الـ amphiarthrosis joints زي الـ intervertebral
+
+284
+00:22:10,700 --> 00:22:13,920
+اللي يعتبر  stable  كمان أكثر هما الأكثر استقرارا
+
+285
+00:22:13,920 --> 00:22:16,380
+اللي هو الأقل حركة  اللي مافيش فيه movement
+
+286
+00:22:16,380 --> 00:22:20,260
+زي الـ sutures of the skull طب أيه ده الـ type of
+
+287
+00:22:20,260 --> 00:22:25,670
+movement؟ الـ type of movement هنا أنا شرحتها قبل
+
+288
+00:22:25,670 --> 00:22:28,390
+شوية وأنا واقفة  أقول أن في عندنا abduction و
+
+289
+00:22:28,390 --> 00:22:32,110
+adduction في عندنا dorsiflexion و plantar flexion
+
+290
+00:22:32,110 --> 00:22:37,270
+لما بنتكلم عن القدم بنتكلم عن dorsiflexion اللي
+
+291
+00:22:37,270 --> 00:22:40,530
+هي flexion and extension plantar اللي أنا بروح
+
+292
+00:22:40,530 --> 00:22:45,830
+بـ رجلي ناحية الـ plantar surface of the foot وفي
+
+293
+00:22:45,830 --> 00:22:51,980
+عندنا flexion و extension و hyperextension كمان في
+
+294
+00:22:51,980 --> 00:22:55,400
+عندنا الـ rotation و circumduction وهو ده وضحنا
+
+295
+00:22:55,400 --> 00:23:01,820
+احنا لما كنا بنتكلم عن أنواع المفاصل الـ uniaxial و
+
+296
+00:23:01,820 --> 00:23:04,340
+الـ multiaxial أو الـ biaxial
+
+297
+00:23:07,170 --> 00:23:09,950
+في عندنا حركة الـ rotation وفي عندنا الـ
+
+298
+00:23:09,950 --> 00:23:13,590
+circumduction وفي كمان حركة فيها supination و
+
+299
+00:23:13,590 --> 00:23:19,070
+pronation هذه متمثلة في الـ radioulnar joints
+
+300
+00:23:19,070 --> 00:23:24,670
+في عندنا حركات في القدم هي عبارة عن الـ eversion و
+
+301
+00:23:24,670 --> 00:23:25,650
+الـ inversion هذه
+
+302
+00:23:25,650 --> 00:23:46,670
+بالقدم
+
+303
+00:23:47,240 --> 00:23:50,320
+الـ head of the humerus و الـ glenoid cavity اللي
+
+304
+00:23:50,320 --> 00:23:53,620
+موجودة في الـ scapula اللي هو عبارة عن ball and
+
+305
+00:23:53,620 --> 00:23:58,300
+socket فيه كرة وفي جوف هو loose joint capsule
+
+306
+00:23:58,300 --> 00:24:02,620
+عشان هيك في عندنا هو mostly free joint أو freely
+
+307
+00:24:02,620 --> 00:24:06,640
+movable joint وفي عندنا bursae  عشان بتعمل
+
+308
+00:24:06,640 --> 00:24:13,260
+مخَدّات أو بتمنع الاحتكاك ما بين العضلات
+
+309
+00:24:13,260 --> 00:24:17,930
+اللي هي بتقوم بالحركة في هذا المكان وطبعا الـ
+
+310
+00:24:17,930 --> 00:24:22,250
+ligaments وظيفتها أنها تقلل من الـ risk of
+
+311
+00:24:22,250 --> 00:24:25,770
+displacement و تمسك الـ two ends of bones هدول في
+
+312
+00:24:25,770 --> 00:24:31,870
+المكان وهو طبعا very movable joint أما الـ
+
+313
+00:24:31,870 --> 00:24:39,590
+shoulder joint طبعا في عندنا حاجة ..
+
+314
+00:24:43,630 --> 00:24:49,590
+الـ shoulder joint هو عبارة عن مفصل محاط بالعديد من الـ
+
+315
+00:24:49,590 --> 00:24:54,070
+ligaments حتى تساعد على حماية هذا المفصل من
+
+316
+00:24:54,070 --> 00:24:57,590
+الزواغات وهو تقريبا من أكثر المفاصل ممكن يكون معرض
+
+317
+00:24:57,590 --> 00:25:04,230
+لـ dislocation نتيجة حوادث الطرق ممكن شد يعني ممكن
+
+318
+00:25:04,230 --> 00:25:06,950
+طفل صغير بس مجرد بنمسكه من أيديه وهيك نروح يحصل
+
+319
+00:25:06,950 --> 00:25:09,650
+عنده وكتفه يحتاج إلى reduction  وبنشوف أن
+
+320
+00:25:09,650 --> 00:25:13,790
+اللاعبين اللي بمصارعة تعرضوا كثير لـ shoulder
+
+321
+00:25:13,790 --> 00:25:18,970
+dislocation لأنه ليس  stable joint وهو طبعا
+
+322
+00:25:18,970 --> 00:25:24,570
+محاط بعدد من الـ ligaments و الـ bursae وغيره أما الـ
+
+323
+00:25:24,570 --> 00:25:32,970
+الـ elbow joint فهو مفصل  يكون  من الـ humerus الـ humerus
+
+324
+00:25:32,970 --> 00:25:37,930
+الـ lower end of humerus فيها trochlea والـ upper
+
+325
+00:25:37,930 --> 00:25:42,780
+end of humerus فيها  اللي اسمها capitulum طبعا فيها
+
+326
+00:25:42,780 --> 00:25:45,780
+أن آخر المجموعات الموجودة  radial joint موجود بين
+
+327
+00:25:45,780 --> 00:25:50,080
+الـ capitulum  والمكان المخصص للـ head of radius على
+
+328
+00:25:50,080 --> 00:25:55,980
+الـ humerus طبعا بيسمح بالحركة في one axis في
+
+329
+00:25:55,980 --> 00:26:01,580
+سطح  اللي حول و خلّينا نقول frontal axis هي
+
+330
+00:26:01,580 --> 00:26:06,380
+flexion and extension و  ملي reinforcing  ملي
+
+331
+00:26:06,380 --> 00:26:09,920
+reinforcing ligaments وهو stable joint ليش stable
+
+332
+00:26:09,920 --> 00:26:14,150
+لأنه less movable  ليس مستقرا  لأن الحركة فيه
+
+333
+00:26:14,150 --> 00:26:17,830
+قليلة ومحاط بالعديد من الـ ligaments و الـ articular
+
+334
+00:26:17,830 --> 00:26:25,460
+surfaces تبعته فيها congruency طبعا هذا شكل الـ
+
+335
+00:26:25,460 --> 00:26:30,220
+elbow joint هو في عندنا هي الـ humerus وهي الـ head
+
+336
+00:26:30,220 --> 00:26:34,180
+of radius وهي محاطة في الـ annular ligament عشان
+
+337
+00:26:34,180 --> 00:26:36,400
+يبقى الـ head of radius كثير من الأطفال لما نجيب
+
+338
+00:26:36,400 --> 00:26:38,720
+ونشدهم ونمسكهم من أيديهم بتلاقي بتطلع الـ head of
+
+339
+00:26:38,720 --> 00:26:43,060
+radius من الـ annular ligament وهذا بيعمل لهم ألم
+
+340
+00:26:43,060 --> 00:26:47,020
+بيحتاج أنه نعملهم حركة خفيفة عشان نرجع المفصل وطبعا
+
+341
+00:26:47,020 --> 00:26:50,040
+على جانبي المفصل في عندنا radial collateral
+
+342
+00:26:50,040 --> 00:26:55,510
+ligament والـ .. و الـ .. الـ ulnar collateral
+
+343
+00:26:55,510 --> 00:26:58,730
+ligament لحماية هذا المفصل
+
+344
+00:27:00,880 --> 00:27:04,580
+أما الـ hip joint طبعا هذا من الـ joints الكبيرة و
+
+345
+00:27:04,580 --> 00:27:07,860
+اللي بتتحمل weight bearing طبعا كثير وهو ball and
+
+346
+00:27:07,860 --> 00:27:12,480
+socket بتكون من الـ head of femur و الـ acetabulum
+
+347
+00:27:12,480 --> 00:27:17,000
+of the pelvis اللي موجودة من الـ .. الـ pelvic bone هو
+
+348
+00:27:17,000 --> 00:27:21,320
+heavy joint capsule لأنه بيتحمل weight bearing كل
+
+349
+00:27:21,320 --> 00:27:25,540
+وزن الجسم بيكون محمل على الـ two hips عشان هيك
+
+350
+00:27:25,540 --> 00:27:30,600
+بتحتاج إلى الكثير من الحماية طبعا الـ reinforcement
+
+351
+00:27:30,600 --> 00:27:35,400
+بتجي من الـ ligaments وطبعا الـ freedom  أكثر مش أقل
+
+352
+00:27:35,400 --> 00:27:38,940
+لكن هي movement in three planes يعني بيعمل flexion,
+
+353
+00:27:39,040 --> 00:27:42,100
+extension, hyperextension, abduction, adduction,
+
+354
+00:27:42,300 --> 00:27:43,820
+medial rotation, lateral rotation و
+
+355
+00:27:43,820 --> 00:27:44,720
+circumduction
+
+356
+00:27:46,880 --> 00:27:50,100
+حكينا أنه ball and socket فبيعمل movement in the
+
+357
+00:27:50,100 --> 00:27:53,080
+three planes طبعا في عندنا العديد من الـ ligaments احنا
+
+358
+00:27:53,080 --> 00:27:56,780
+عارفين أن عظام الحوض عبارة عن الـ ilium و الـ
+
+359
+00:27:56,780 --> 00:28:00,500
+ischium و الـ pubis  ده اللي احنا شايفينه هنا فلازم أنه
+
+360
+00:28:00,500 --> 00:28:06,030
+بيكون في عندنا ligaments بتربط الـ femur مع هدول
+
+361
+00:28:06,030 --> 00:28:09,750
+العظام  وبنشوف هنا متشابكة  وبجانب أن في
+
+362
+00:28:09,750 --> 00:28:13,970
+مكان كان موجود داخل من الـ head نفسه إلى الـ
+
+363
+00:28:13,970 --> 00:28:18,190
+acetabulum هذا عامل زي كأنه زي مسمار كده بس هو رباط
+
+364
+00:28:18,190 --> 00:28:24,860
+منه طبعا موجود بيربط الـ head مع الـ acetabulum و
+
+365
+00:28:24,860 --> 00:28:30,980
+حواليه في الـ iliofemoral ligament وفي الـ ischiofemoral
+
+366
+00:28:30,980 --> 00:28:35,340
+ligament وفي الـ pubofemoral ligament وهدول ligaments
+
+367
+00:28:35,340 --> 00:28:41,480
+قوية جدا  من  هي dense tissue طبعا dense
+
+368
+00:28:41,480 --> 00:28:45,780
+fibrous tissue عشان تساعد في الـ stability أما
+
+369
+00:28:45,780 --> 00:28:48,640
+الـ knee joint بتقولنا هو most complex joint و الـ
+
+370
+00:28:48,640 --> 00:28:53,480
+largest joint of the body طبعا بيحمل وزن أكثر كمان
+
+371
+00:28:53,480 --> 00:28:56,520
+من الوزن اللي بيحمله الـ head لأن هو بياخد وزن
+
+372
+00:28:56,520 --> 00:29:01,440
+الجسم كله  الجزء السفلي كله  في عندنا medial و lateral
+
+373
+00:29:01,440 --> 00:29:05,940
+condyle of the femur  في مرض تلتحم الـ medial و
+
+374
+00:29:05,940 --> 00:29:10,480
+lateral condyles of the proximal end of the tibia
+
+375
+00:29:10,480 --> 00:29:14,360
+,femur articulates anteriorly with العظمة الساقية
+
+376
+00:29:14,360 --> 00:29:18,420
+اللي بنسميها  الشظية اللي هي  tibia,modified
+
+377
+00:29:18,420 --> 00:29:21,700
+hinge joint طبعا ليش modified لأنه بيسمح
+
+378
+00:29:21,700 --> 00:29:24,930
+بـ flexion, extension و القليل من الـ rotation فيه
+
+379
+00:29:24,930 --> 00:29:28,310
+flexion position طبعا strengthened by many
+
+380
+00:29:28,310 --> 00:29:32,810
+ligaments و الـ menisci اللي هي الـ menisci عبارة
+
+381
+00:29:32,810 --> 00:29:35,910
+عن المخدات الموجودة في المفصل عشان تساعد الـ
+
+382
+00:29:35,910 --> 00:29:39,650
+congruence في المفصل وتساعد على الـ stability و
+
+383
+00:29:39,650 --> 00:29:43,290
+many ligaments زي ما احنا شايفين عشان تسهل عملية
+
+384
+00:29:43,290 --> 00:29:48,270
+الحركة وهي الـ movement تبعته بتكون في الـ sagittal
+
+385
+00:29:48,270 --> 00:29:53,110
+plane طبعا الـ complexity بتزيد من عدد من الـ
+
+386
+00:29:53,110 --> 00:29:56,750
+ligaments اللي موجودة، في عندنا حاجة اسمها إكراشية
+
+387
+00:29:56,750 --> 00:29:59,350
+في الـ ligaments، في عندنا two menisci medial و
+
+388
+00:29:59,350 --> 00:30:01,830
+lateral، في عندنا الـ lateral collateral ligament،
+
+389
+00:30:01,830 --> 00:30:05,700
+في عندنا الـ medial collateral ligament و الـ
+
+390
+00:30:05,700 --> 00:30:09,500
+الـ fibular طبعا الـ fibular على ناحية الـ fibula
+
+391
+00:30:09,500 --> 00:30:13,400
+الـ lateral والـ medial collateral ligament هو على
+
+392
+00:30:13,400 --> 00:30:16,880
+الـ tibia بنسميه tibial collateral ligament هذه كلها
+
+393
+00:30:16,880 --> 00:30:22,280
+الـ .. الـ .. الـ ligaments  هتساعد على الـ stability
+
+394
+00:30:22,280 --> 00:30:27,820
+of the knee joint و تسمح طبعا بالحركة التغيرات اللي
+
+395
+00:30:27,820 --> 00:30:31,580
+بتصير joint stiffness دائما هي early sign of
+
+396
+00:30:31,580 --> 00:30:34,520
+aging بتبقى أن الـ flexibility بتاعت الجوانت
+
+397
+00:30:34,520 --> 00:30:37,600
+بتقل، الـ fibrous tissues طبعا أول حاجة بتصير
+
+398
+00:30:37,600 --> 00:30:42,980
+strengthening لأنها بتقل مرونتها  طبعا في الـ
+
+399
+00:30:42,980 --> 00:30:46,630
+synovial joints و الـ vertebral column كلها
+
+400
+00:30:46,630 --> 00:30:49,470
+بتصير diminished flexibility و
+
+445
+00:34:02,140 --> 00:34:08,340
+على المفاصل وهذه تقريباً الصورة لبعد المفاصل التي
+
+446
+00:34:08,340 --> 00:34:11,950
+ممكن تكون، يعني الفرق بين الـ normal joints و بين الـ
+
+447
+00:34:11,950 --> 00:34:16,190
+osteoarthritic joints. فإحنا في نهاية محاضرتنا
+
+448
+00:34:16,190 --> 00:34:19,710
+لليوم، إحنا اتكلمنا فيها عن الـ articulations أو الـ
+
+449
+00:34:19,710 --> 00:34:22,750
+joints of the... of the body، وقلنا تعرّفنا على
+
+450
+00:34:22,750 --> 00:34:27,830
+أهميتها، وكمان على أنواعها، وعرفنا الفرق بين الـ
+
+451
+00:34:27,830 --> 00:34:31,930
+uniaxial والـ biaxial والـ multiaxial joints، و
+
+452
+00:34:31,930 --> 00:34:36,150
+عرفنا أن أهم شيء أنه ال... ال... ال... ال...
+
+453
+00:34:36,150 --> 00:34:40,530
+التناسب العكسي ما بين الـ mobility and stability of
+
+454
+00:34:40,530 --> 00:34:43,710
+the joints، وإن شاء الله في المحاضرة القادمة هيكون
+
+455
+00:34:43,710 --> 00:34:46,390
+موضوعنا عن الـ nervous system. لكم، إن شاء الله، في
+
+456
+00:34:46,390 --> 00:34:47,250
+المحاضرة القادمة.
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..21f643197c0ba9dfe8ee9696c9532e8fd89fb16b
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY_postprocess.srt
@@ -0,0 +1,1824 @@
+1
+00:00:04,940 --> 00:00:08,860
+بسم الله الرحمن الرحيم و الصلاة والسلام على سيدنا
+
+2
+00:00:08,860 --> 00:00:12,600
+محمد سيد المرسلين، اليوم محاضرتنا استكمال لل
+
+3
+00:00:12,600 --> 00:00:17,120
+skeletal system، في جزء مهم في ال skeletal system،
+
+4
+00:00:17,120 --> 00:00:22,120
+لازم نتعرف عليه، هو ال joints or ال articulations
+
+5
+00:00:22,610 --> 00:00:27,030
+طبعا أش وظيفة ال joints هي بترتبط بين two adjacent
+
+6
+00:00:27,030 --> 00:00:31,250
+و تعريف ال joints يعني اللي هو ال wrap between two
+
+7
+00:00:31,250 --> 00:00:37,070
+adjacent bone يعني عضمة يان يكونوا بشكل مفصل عن
+
+8
+00:00:37,070 --> 00:00:42,010
+طريقالتحام هم و طبعا الاتحام هذا بيكون حسب شكل
+
+9
+00:00:42,010 --> 00:00:46,450
+المفصل بتعطينا نوع الحركة، يبقى أول حاجة ال joints
+
+10
+00:00:46,450 --> 00:00:49,350
+هي اللي بتربط العضام مع بعضها و بتخلينا احنا
+
+11
+00:00:49,350 --> 00:00:53,450
+واقفين هيك، احنا لو ماكنش في عندنا joints فبيكون
+
+12
+00:00:53,450 --> 00:00:56,750
+احنا بنشتغل زي ال robot مافيش امكانية ان احنا لا
+
+13
+00:00:56,750 --> 00:00:59,970
+نتنقض ايدينا ولا نتنقض أجلينا ولا نتحرك، هتحرك
+
+14
+00:00:59,970 --> 00:01:06,460
+بصورة خلنا نقول متصلبةفال .. يبقى ال articulations
+
+15
+00:01:06,460 --> 00:01:14,120
+بتساعدني على الحركة و كمانبتساعد على النمو كيف لو
+
+16
+00:01:14,120 --> 00:01:18,600
+احنا نولدنا بنفس الحجم هذا فكان طبعا مستحيل عملية
+
+17
+00:01:18,600 --> 00:01:21,040
+الحمل و الولادة هذا تصير فعشان هيك احنا ولدنا
+
+18
+00:01:21,040 --> 00:01:25,880
+باحجام صغيرة و كان لازم عملية النمو طبيعي هاد تكون
+
+19
+00:01:25,880 --> 00:01:31,600
+فعشان هيك كان في نهاية العضمة قبل ما يبدأ المفصل
+
+20
+00:01:31,600 --> 00:01:35,280
+في عندنا في ال epiphysis في عندنا الepiphysial
+
+21
+00:01:35,280 --> 00:01:43,290
+growth فكان في عملية النمو للعظامكمان بتساعدنا على
+
+22
+00:01:43,290 --> 00:01:51,230
+التغيير الشكل العظام أثناء النمو وكمان بتساعد على
+
+23
+00:01:51,230 --> 00:01:55,430
+ال movement من خلال ال articulations من خلال
+
+24
+00:01:55,430 --> 00:01:58,990
+العضلات اللي بتكون حوالين المنفع الصلمي
+
+25
+00:02:03,070 --> 00:02:06,350
+كيف احنا سمينا هذه الإضاءة أو كيف العلماء سموا
+
+26
+00:02:06,350 --> 00:02:14,410
+هدولة الإضاءة؟ طبعا الاسم دايما derived من ال
+
+27
+00:02:14,410 --> 00:02:19,230
+articulations bone يعني ال tibia مع ال femur
+
+28
+00:02:19,230 --> 00:02:24,570
+هتعطيني ال knee ال humerus and ulnar مع ال radius
+
+29
+00:02:24,570 --> 00:02:31,090
+هتعطيني ال elbowو هكذا اللي قدها حسب ترتيبها هتكون
+
+30
+00:02:31,090 --> 00:02:35,630
+أسماء ال articulations حتى و كمان أنواعها اللي
+
+31
+00:02:35,630 --> 00:02:40,570
+بتعتمد على shape of the articular surfaces طبعا
+
+32
+00:02:40,570 --> 00:02:41,910
+تقسيمتها
+
+33
+00:02:44,110 --> 00:02:51,330
+يتقسمت بصراحة حسب الحركة وحسب شكل المفصل نروح ل ال
+
+34
+00:02:51,330 --> 00:02:57,550
+fibrous joints هي عبارة عن dense connective tissue
+
+35
+00:02:57,550 --> 00:03:04,650
+تجمع ال bones togetherالـ bones بيكون متلاسقة جدا
+
+36
+00:03:04,650 --> 00:03:08,090
+يعني بيكون فش فراغات بين ال bone يعني فش real
+
+37
+00:03:08,090 --> 00:03:13,270
+articulation الحقيقة two bones adjacent مرتبطين مع
+
+38
+00:03:13,270 --> 00:03:18,070
+بعضهم لكن فش كتير منها movement أما ال
+
+39
+00:03:18,070 --> 00:03:22,750
+cartilaginousفهي عبارة عن يالين كارتيلاج وفيبرو
+
+40
+00:03:22,750 --> 00:03:26,250
+كارتيلاج connected bone في هذا الشكل يعني خلنا
+
+41
+00:03:26,250 --> 00:03:29,430
+نقول ال fibers نكون في عضمتين جانب بعض احنا الحركة
+
+42
+00:03:29,430 --> 00:03:33,630
+فيهم مش ضرورية لكن لازم يكون في خلينا نقول
+
+43
+00:03:33,630 --> 00:03:38,110
+الالتصاق تبع العضمات أو ال stability تبع العضمتين
+
+44
+00:03:38,110 --> 00:03:43,160
+مع بعض الكارتيلاج لأ بتختلف شوية انهفي عندنا
+
+45
+00:03:43,160 --> 00:03:47,360
+التقام للعضلات لكن مش مباشر في عندنا cartilage او
+
+46
+00:03:47,360 --> 00:03:53,660
+fibrocartilage او او disk او اذا نقول ال disk في
+
+47
+00:03:53,660 --> 00:03:56,180
+عندنا الaneously process وفي عندنا ال nucleus اللي
+
+48
+00:03:56,180 --> 00:04:00,940
+هي بتساعد على ال fabrication لل joints و بتساعد
+
+49
+00:04:00,940 --> 00:04:04,500
+على الحركة البسيطة اما ال synivial joints وهذه ال
+
+50
+00:04:04,500 --> 00:04:06,900
+joints الكبيرة اللي موجودة المفاصلة الكبيرة زي ال
+
+51
+00:04:06,900 --> 00:04:11,220
+elbow و الhipهدولة بيكون أول حاجة ال complex لإن
+
+52
+00:04:11,220 --> 00:04:13,520
+تركيبها وال articular shared surface والسينوبيا
+
+53
+00:04:13,520 --> 00:04:17,060
+الفلود وال ligaments جوا وال ligaments برا و بتكون
+
+54
+00:04:17,060 --> 00:04:20,680
+محاطة بالسينوبيا ال membrane و هكذا هذه هي الإضام
+
+55
+00:04:20,680 --> 00:04:24,740
+اللي احنا بتساعد على الحركة الكبيرة اللي احنا
+
+56
+00:04:24,740 --> 00:04:28,580
+بنتحركها سواء في الambulation أو ال locomotion أو
+
+57
+00:04:28,580 --> 00:04:34,660
+في المصول للأشياءالانواع لو .. لو اجينا اتكلمنا
+
+58
+00:04:34,660 --> 00:04:39,560
+على ال .. يعني صنفوناها according to the movement
+
+59
+00:04:39,560 --> 00:04:42,960
+فبنلاقي أنه إلها تصنيفة تانية هي ال scene
+
+60
+00:04:42,960 --> 00:04:47,120
+arthrosis ال immovable bone و ال amphiarthrosis ال
+
+61
+00:04:47,120 --> 00:04:50,300
+slightly movable joint و ال diathrosis اللي هي زي
+
+62
+00:04:50,300 --> 00:04:54,800
+ال synovial joints فهي freely movable joints
+
+63
+00:04:57,100 --> 00:05:00,600
+ناخد أنواع أو أشكال الـfibrous genes هنلاقيها
+
+64
+00:05:00,600 --> 00:05:04,940
+three type بيسموها الـsyndesmosis والسوشر
+
+65
+00:05:04,940 --> 00:05:09,680
+والكمفوزس طيب إيش الفرق ما بينهم؟ الـsyndesmosis
+
+66
+00:05:09,680 --> 00:05:14,080
+فهو عبارة عن sheet between two bones زي ما إحنا
+
+67
+00:05:14,080 --> 00:05:20,020
+شايفين في الصورة اللي على اليمين هنا أو على يسار
+
+68
+00:05:20,020 --> 00:05:25,260
+الصورةانه فيه ان الـ tibia and fibula موجود في
+
+69
+00:05:25,260 --> 00:05:28,600
+بينهم كده غشاء، الغشاء هذا رابط هدول العدمتين عشان
+
+70
+00:05:28,600 --> 00:05:32,400
+يكونوا أكتر stability، هم العدمتين مرتبطين من تحت
+
+71
+00:05:32,400 --> 00:05:37,380
+المفصل و من فوق المفصل، المفصلين هدول مش متحركين،
+
+72
+00:05:37,380 --> 00:05:43,010
+تمام؟ف sheet or bundle of fibrous tissue connect
+
+73
+00:05:43,010 --> 00:05:46,570
+the bone هنا أما في أثرات يعني slightly movable
+
+74
+00:05:46,570 --> 00:05:49,910
+joints مابتتحركش كتير يعني هي بتسمح بالحركة
+
+75
+00:05:49,910 --> 00:05:55,210
+القليلة جدا ودايما يعني أكتر مثل نضرب عليها اللي
+
+76
+00:05:55,210 --> 00:05:59,810
+هو ال joints between tibia and fibulaالـ suture
+
+77
+00:05:59,810 --> 00:06:04,350
+طبعا احنا كلنا بنعرف انه الـ skull مجموعة من الـ
+
+78
+00:06:04,350 --> 00:06:07,590
+bones زي ما اتكلمنا فيه عينة frontal و parietal و
+
+79
+00:06:07,590 --> 00:06:11,150
+temporal و occipital هدولة بيشكلوا الـ skull ولا
+
+80
+00:06:11,150 --> 00:06:15,090
+في الأول في بينهم فيه foramen تمام؟ حالتا لما
+
+81
+00:06:15,090 --> 00:06:18,790
+بيتحم هذا ال foramen بيصير على شكل suture زي اللي
+
+82
+00:06:18,790 --> 00:06:23,290
+احنا شايفينها بالرسم كأنه مخيطة خياطة هذه خياطة
+
+83
+00:06:23,290 --> 00:06:27,560
+ربانيةهي تربط يبقى الـ suture تربط between the
+
+84
+00:06:27,560 --> 00:06:31,660
+flat bone وهي sinarthrosis، sinarthrosis يعني إنها
+
+85
+00:06:31,660 --> 00:06:35,640
+innovable joints، thin layer of connective tissue
+
+86
+00:06:35,640 --> 00:06:38,600
+connect the bone وزي ما احنا شايفناه، أما
+
+87
+00:06:38,600 --> 00:06:46,200
+الجنفاصيز يوز هي عبارة عن غذر تبع ال teethهي cone
+
+88
+00:06:46,200 --> 00:06:50,940
+-shaped bone process in a socket يعني في جيب شكل
+
+89
+00:06:50,940 --> 00:06:56,320
+مخلوطي عبنة مخلوطية الشكل مزروعة وين مزروعة في
+
+90
+00:06:56,320 --> 00:07:01,200
+مكان معين في جيب معين زي ال tooth in the jawbone
+
+91
+00:07:01,200 --> 00:07:04,920
+طبعا احنا بنعرف ان كل سن في الجذر الجذر هذا موجود
+
+92
+00:07:04,920 --> 00:07:08,780
+في اللثةوهذه sinarthrosis يعني تخيلنا أنها لو انها
+
+93
+00:07:08,780 --> 00:07:12,200
+movable كان احنا عمرنا ما عرفنا نمضغ او ناكل يبقى
+
+94
+00:07:12,200 --> 00:07:16,900
+السنان مثبتة و احنا بنرى لو هذا المفصل صار يعني
+
+95
+00:07:16,900 --> 00:07:22,360
+متراخ شوية بيعني القلم الجدير بيقدي نخلع هذا السن
+
+96
+00:07:22,360 --> 00:07:28,100
+فهي sinarthrosis no means no movement زي هذا الشكل
+
+97
+00:07:28,100 --> 00:07:34,080
+اللي احنا شايفه جدر السنأما ال cartilaginous فهي
+
+98
+00:07:34,080 --> 00:07:39,500
+synchondrosis مش متحركة زي ال .. ال .. ال .. ال ..
+
+99
+00:07:39,500 --> 00:07:42,800
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+100
+00:07:42,800 --> 00:07:43,740
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+101
+00:07:43,740 --> 00:07:43,780
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+102
+00:07:43,780 --> 00:07:45,800
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+103
+00:07:45,800 --> 00:07:45,860
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+104
+00:07:45,860 --> 00:07:46,700
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+105
+00:07:46,700 --> 00:07:46,760
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+106
+00:07:46,760 --> 00:07:46,840
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+107
+00:07:46,840 --> 00:07:54,010
+.. ال .. ال .. اليبقى synchondrosis bone of
+
+108
+00:07:54,010 --> 00:07:56,870
+yelling cartilage you need that bone يعني احنا
+
+109
+00:07:56,870 --> 00:08:00,830
+بلاقي كل rib في نهايتها زي ما احنا شايفين في عندنا
+
+110
+00:08:00,830 --> 00:08:03,750
+cartilage بتسميه costal cartilage بيعمل
+
+111
+00:08:03,750 --> 00:08:06,610
+attachments مع الاستيرنام
+
+112
+00:08:07,990 --> 00:08:11,750
+في الانفيزيا للبلاد طبعا هذا البلاد اللى بيسمح
+
+113
+00:08:11,750 --> 00:08:16,290
+بعملية انمو عساس انه كل ما بنكبر كل ما بيكبر هذا
+
+114
+00:08:16,290 --> 00:08:22,130
+بيصير ossification و بيساعد على طول العظام كمان
+
+115
+00:08:22,130 --> 00:08:29,090
+هدولة seen arthrosis يعني غير متحركة or immovable
+
+116
+00:08:31,330 --> 00:08:34,730
+أما الـ Synthesis هذا النوع التاني فهي Ibad-O
+
+117
+00:08:34,730 --> 00:08:37,830
+-Fibrocartilage between the bone شوفناها في
+
+118
+00:08:37,830 --> 00:08:41,130
+المحاضرة اللي فاتت في ال Pupic Synthesis اللي
+
+119
+00:08:41,130 --> 00:08:47,610
+بيعمل LTA blood to pupic bone في البلفكبونjoints
+
+120
+00:08:47,610 --> 00:08:50,710
+between bodies of adjacent vertebrae قولنا each
+
+121
+00:08:50,710 --> 00:08:55,210
+vertebra between two adjacent vertebra في عندنا ال
+
+122
+00:08:55,210 --> 00:08:59,030
+intervertebral دسكي موضح بالرسم وهو دي لأ
+
+123
+00:08:59,030 --> 00:09:03,250
+amphiarthrosis means انه slightly movable joints
+
+124
+00:09:03,250 --> 00:09:04,830
+عشان تسمح بالحركة
+
+125
+00:09:07,150 --> 00:09:10,790
+أما الـ Synovial فهو الـ most complicated joints
+
+126
+00:09:10,790 --> 00:09:16,710
+هي منتشرة على معظم مفاصل الجسم اللي فيها real
+
+127
+00:09:16,710 --> 00:09:21,190
+movement a basic feature أول حاجة أنها بتحتوي على
+
+128
+00:09:21,190 --> 00:09:27,670
+articular capsule في جيب كده أو شاق محيط بالمفصل
+
+129
+00:09:28,410 --> 00:09:33,450
+أيضًا فيها سينوفيول كافتي تبقى full of سينوفيول
+
+130
+00:09:33,450 --> 00:09:37,090
+fluid عشان يساعد على تغذية ال cartilage ويساعد
+
+131
+00:09:37,090 --> 00:09:40,510
+كمان على ال movement ويعمل نوع من ال lubricant
+
+132
+00:09:40,510 --> 00:09:44,550
+inside the joints فيعنى ال article ال cartilage
+
+133
+00:09:44,550 --> 00:09:48,830
+اللي هو covering ال heads أو خليني أقول ال
+
+134
+00:09:48,830 --> 00:09:53,550
+epiphysisال contact bone مع ال other bone لازم
+
+135
+00:09:53,550 --> 00:09:58,530
+تكون مادة نسقولة جدا مثل ال cartilage و نعمة أي
+
+136
+00:09:58,530 --> 00:10:01,990
+خشونة في هذه ال .. في هذا ال cartilage ممكن يؤدي
+
+137
+00:10:01,990 --> 00:10:05,990
+إلى .. إلى pain و ligaments ليش؟ ال ligaments هي
+
+138
+00:10:05,990 --> 00:10:10,470
+الأربطة اللي بتربط هدولة العضمتين مع بعض حتى تمنع
+
+139
+00:10:10,470 --> 00:10:14,670
+الزواغان المفصل و كمان nerves و blood vessels ال
+
+140
+00:10:14,670 --> 00:10:20,270
+nerve عشان تعطيني laser orderكمان بيكون ال .. ال
+
+141
+00:10:20,270 --> 00:10:26,170
+bones احنا حكينا innervated أما ال cartilage لأ و
+
+142
+00:10:26,170 --> 00:10:28,590
+ال blood vessels قلنا ال cartilage is not
+
+143
+00:10:28,590 --> 00:10:29,890
+vascularized
+
+144
+00:10:33,590 --> 00:10:39,210
+نروح لل Anatomy of the synovial joint ال Accessory
+
+145
+00:10:39,210 --> 00:10:42,930
+Structure فيها إن حاجة اسمها ال PORSAE ال PORSAE
+
+146
+00:10:42,930 --> 00:10:49,010
+هي عبارة عن sack جابة فيها synovial fluid هذه
+
+147
+00:10:49,010 --> 00:10:52,530
+بتكون موجودة في الأماكن الاحتكاك عشان تمنع
+
+148
+00:10:52,530 --> 00:10:55,090
+الاحتكاك أثناء الحركة يبقى هي
+
+149
+00:11:03,670 --> 00:11:07,150
+أما في كمان نوع تاني من المخدات خلينا نسميهم مخدات
+
+150
+00:11:07,150 --> 00:11:10,870
+احنا اللي هي الـ fat pads دايما distributed along
+
+151
+00:11:10,870 --> 00:11:14,170
+the peripheral of the synovial joint في جوانب ال
+
+152
+00:11:14,170 --> 00:11:19,280
+peripheral joint act as backing materialand it
+
+153
+00:11:19,280 --> 00:11:23,320
+provides some protection بتساعد على حماية هذا
+
+154
+00:11:23,320 --> 00:11:30,520
+المفصل دايما بتملأ الفراغات بين العظام عشان تساعد
+
+155
+00:11:30,520 --> 00:11:34,720
+على ال stability و بتحسن من ال congrance of the
+
+156
+00:11:34,720 --> 00:11:39,280
+joint ايش ال congrance اللي هو تطابق ال joints
+
+157
+00:11:39,280 --> 00:11:44,960
+نفسه؟أما الـ tail bones فهي نهايات ال muscles اللي
+
+158
+00:11:44,960 --> 00:11:47,940
+بتعمل attachment with the bone دائما بال
+
+159
+00:11:47,940 --> 00:11:54,180
+stabilization of the joint وهذا خلينا نقول شكل ال
+
+160
+00:11:54,180 --> 00:11:58,680
+knee joint هو تقريبا ال most complicated joint in
+
+161
+00:11:58,680 --> 00:12:05,050
+the bodyلأنه في كتير من ال .. خليني نقول الأجزاء
+
+162
+00:12:05,050 --> 00:12:10,370
+زي ال articular surfaces زي ال patella، في عندنا
+
+163
+00:12:10,370 --> 00:12:16,250
+ال .. ال intervertebral menisci، في عندنا ال
+
+164
+00:12:16,250 --> 00:12:18,490
+ligaments، في عندنا الكرشيات، ال ligaments، اللي
+
+165
+00:12:18,490 --> 00:12:23,550
+هنشرحهمواحد واحد فهي البورصة هي هذه عشان تعملي
+
+166
+00:12:23,550 --> 00:12:27,650
+passages لتندو زي البنت تندو باتيلا بيكون في عندنا
+
+167
+00:12:27,650 --> 00:12:34,970
+البورصة هي أساس انها تساعد في الحركة هذا هنشرحه
+
+168
+00:12:34,970 --> 00:12:40,240
+عندما نوصل للمفصل البنانيوهذا شكل تاني للـ Tendon
+
+169
+00:12:40,240 --> 00:12:43,820
+Sheets اللي موجودة في ال wrist هذي ال sheets
+
+170
+00:12:43,820 --> 00:12:49,320
+بتساعد على إنه تخلي ال tendons هذه الأوتار هذه في
+
+171
+00:12:49,320 --> 00:12:52,400
+أماكنها لو كان افترضنا إنه فيه مشكلة في واحد من
+
+172
+00:12:52,400 --> 00:12:56,620
+هال sheets هذه هذا ممكن يؤدي لإنه ال tendon
+
+173
+00:12:56,620 --> 00:13:00,460
+مايكونش stable ويعلق يعني مثلما ال trigger fingers
+
+174
+00:13:00,460 --> 00:13:03,340
+أحيانا بيكون له الشخص بيقدر يطني أصابعه لكن
+
+175
+00:13:03,340 --> 00:13:06,240
+مابيقدر يفردها فهذه بيكون فيه مشكلة في ال tendon
+
+176
+00:13:06,240 --> 00:13:07,040
+sheets
+
+177
+00:13:11,740 --> 00:13:15,140
+أما الـ type of joint فاحنا بدنا نعرف أنه في عندنا
+
+178
+00:13:15,140 --> 00:13:20,220
+joints مختلفة ال .. ال access اتكلم عن ال access
+
+179
+00:13:20,220 --> 00:13:24,540
+إذا بنتذكر في أول محاضرة قيلنا أو عرفنا في عندنا
+
+180
+00:13:24,540 --> 00:13:29,140
+ال .. ال plans of movement ال frontal و ال .. و ال
+
+181
+00:13:29,140 --> 00:13:35,000
+sagittal و ال transfers و كل واحد من هدول ال .. ال
+
+182
+00:13:35,000 --> 00:13:39,020
+plans له access فال movement بتصير within the plan
+
+183
+00:13:39,020 --> 00:13:43,510
+around an axisفيه ان بعض ال joints بس ال movement
+
+184
+00:13:43,510 --> 00:13:48,390
+around uniaxial يعني one axis او biaxial او two
+
+185
+00:13:48,390 --> 00:13:52,930
+plans او multiaxial او three plans يعني فلينا احنا
+
+186
+00:13:52,930 --> 00:13:57,710
+نمثل هذا انا بس بدي اوقف لو احنا تكلمنا مثل عن ال
+
+187
+00:13:57,710 --> 00:14:02,410
+shoulder joints هو three axial joints يعني ان انا
+
+188
+00:14:02,410 --> 00:14:05,990
+بقدر اعمل ال movement flexureextension,
+
+189
+00:14:06,270 --> 00:14:11,770
+hyperextension, abduction, adduction, lateral
+
+190
+00:14:11,770 --> 00:14:16,410
+rotation, medial rotation وكمان في حركة هي ال
+
+191
+00:14:16,410 --> 00:14:18,730
+circumduction ايش ال circumduction يعني ان انا
+
+192
+00:14:18,730 --> 00:14:22,720
+بقدر اعمل هذه الحركة في three different axisطيب
+
+193
+00:14:22,720 --> 00:14:27,140
+هذا ليش انا بقدر اشتغل بال shoulder بهذا الشكل او
+
+194
+00:14:27,140 --> 00:14:30,580
+بقدر اعمل هذا ال movement لأن هو semivial joints
+
+195
+00:14:30,580 --> 00:14:34,000
+هو if really movable joints و ال articular
+
+196
+00:14:34,000 --> 00:14:39,740
+surfaces بتسمحلي بهذا النوع من الحركة يعني ان يكون
+
+197
+00:14:39,740 --> 00:14:41,140
+في عندي حركة بال
+
+198
+00:14:56,970 --> 00:15:03,270
+الشكل المفصل هو اللي بيسمح هذا النوع من الحركة
+
+199
+00:15:16,660 --> 00:15:22,060
+deviation median هنا احنا بنسميه Palmer deviation
+
+200
+00:15:22,060 --> 00:15:26,460
+وعلى ال letter n بنسميه radial deviation يبقى في
+
+201
+00:15:26,460 --> 00:15:29,400
+ال anatomical position انا بقدر اعمل flexion
+
+202
+00:15:29,400 --> 00:15:30,580
+extension
+
+203
+00:15:37,960 --> 00:15:42,440
+النتا كاربو فلانجيال جوانز انا بعمل flexion,
+
+204
+00:15:43,120 --> 00:15:49,180
+extension, abduction, adductionأما نروح على الـ
+
+205
+00:15:49,180 --> 00:15:53,260
+Uniaxial زي ال .. ال .. ال elbow joints و ال knee
+
+206
+00:15:53,260 --> 00:15:57,880
+joint as well أنا بقدر أعمل بس flexion extension
+
+207
+00:15:57,880 --> 00:16:01,060
+ال movement هنا عندي بس في الـ Sagittal plane
+
+208
+00:16:01,060 --> 00:16:04,920
+around the frontal axis Sagittal plane around the
+
+209
+00:16:04,920 --> 00:16:08,860
+frontal axis وهذه من ناحية سمية نوع الجد الهنج جد
+
+210
+00:16:08,860 --> 00:16:14,210
+وهلأ هنتعرف على أنواع الجديعني كان هذا أهم إشي في
+
+211
+00:16:14,210 --> 00:16:19,970
+موضوعنا لليوم أما ال types of joints فعنا ال
+
+212
+00:16:19,970 --> 00:16:23,890
+planner ال gliding joint اللي هي ال movement بتكون
+
+213
+00:16:23,890 --> 00:16:29,230
+بس حركة movement بسيطة gliding ال hinge زي ما
+
+214
+00:16:29,230 --> 00:16:34,710
+حكينا وورينا قبل شوية زي ال elbowأما الـ pivot فهي
+
+215
+00:16:34,710 --> 00:16:38,050
+حركة الدوران في حركة ال rotation اللي احنا قبل
+
+216
+00:16:38,050 --> 00:16:42,630
+شوية حكيناها بس بتكون خاصة بس بمفصل نوع ال joint
+
+217
+00:16:42,630 --> 00:16:48,090
+pivot اللي هي حركة دوران ال neck to the right and
+
+218
+00:16:48,090 --> 00:16:53,290
+to the left أما ال combo load joint والصدل joint
+
+219
+00:16:53,290 --> 00:16:58,710
+هنتعرف عليهم one by oneوأكبر المفاصل عندنا بتكون
+
+220
+00:16:58,710 --> 00:17:03,690
+عبارة عن ball and socket في عندنا كرة وموجودة في
+
+221
+00:17:03,690 --> 00:17:08,890
+جيب تحتضنها في هدى بتاعة movement في every plant
+
+222
+00:17:08,890 --> 00:17:14,290
+like the shoulder and the hipنبدأ بالـ Bowel and
+
+223
+00:17:14,290 --> 00:17:19,350
+Socket اللي هو من المفاصلة الـ freely movable
+
+224
+00:17:19,350 --> 00:17:24,910
+joints وفيها movement in the three plans زي ال
+
+225
+00:17:24,910 --> 00:17:32,010
+shoulder and hip joint طيب نشوف أن على الشكل هنا
+
+226
+00:17:32,010 --> 00:17:36,290
+ال hip مهم في عين الأسيطابيولام وفي عين ال head of
+
+227
+00:17:36,290 --> 00:17:49,150
+femurعاملين زي كأنها كرة جوات يعني حاوية وفي
+
+228
+00:17:49,150 --> 00:17:54,210
+عندنا النقطة
+
+229
+00:17:54,210 --> 00:17:58,360
+تانيةزي ما احنا شايفين الـ Condyloid Joint بهذا
+
+230
+00:17:58,360 --> 00:18:01,540
+الشكل الـ Condyloid برضه بيعطينا movement بس in
+
+231
+00:18:01,540 --> 00:18:05,080
+two plan او by axial plan زي الـ
+
+232
+00:18:05,080 --> 00:18:07,960
+Metacarpophalangeal Joints اللي وضحناها قبل شوية
+
+233
+00:18:07,960 --> 00:18:13,500
+ال Condyloid بين ال Metacarpophalangeal Joints اما
+
+234
+00:18:13,500 --> 00:18:20,330
+ال gliding joint فهي عبارةmovement of gliding
+
+235
+00:18:20,330 --> 00:18:25,890
+between the tarsal and carpal bone إذا بتذكروا في
+
+236
+00:18:25,890 --> 00:18:29,910
+الانترن يقولنا في عنا two rows of carpal bone ال
+
+237
+00:18:29,910 --> 00:18:33,030
+proximal row والدستر روه ال movement ما بينهم
+
+238
+00:18:33,030 --> 00:18:37,690
+بتكون فقط gliding بس إزاحة عملية إزاحة أما ال
+
+239
+00:18:37,690 --> 00:18:44,750
+hinge joint فهي عبارة عن ال elbow and knee وكمان
+
+240
+00:18:44,750 --> 00:18:48,450
+between the phalanges أو ال interphalangeal joints
+
+241
+00:18:50,030 --> 00:18:53,350
+طبعا الشيء اللي بيحدد الحركة قلنا شكل المفصل
+
+242
+00:18:53,350 --> 00:18:56,610
+تخيلنا شكل المفصل حسب الصورة بنلاقي أن شكل المفصل
+
+243
+00:18:56,610 --> 00:19:01,550
+ما بيسمح إلا بحركة بهذا الاتجاه أما ال pivot فهو
+
+244
+00:19:01,550 --> 00:19:06,290
+عبارة عن حركة دوران حوالي المحور الحركة هذه إذا ما
+
+245
+00:19:06,290 --> 00:19:09,670
+اتذكر لما اتكلمنا عن ال Atlas و ال Axis اللي هما
+
+246
+00:19:09,670 --> 00:19:14,090
+ال first and second cervical vertebra فقولناالـ
+
+247
+00:19:14,090 --> 00:19:18,470
+Axis فيه إلها الـ Odontoid process فيه هي process
+
+248
+00:19:18,470 --> 00:19:23,910
+موجود في الفتحة أو في الفرمن في ال Axis لأن هما
+
+249
+00:19:23,910 --> 00:19:28,290
+كانت إشكالهم كانت مختلفة إذا بتذكروا وإنها بتسمح
+
+250
+00:19:28,290 --> 00:19:35,980
+بحركة ال rotation هذه بتشكل pivot jointأما السد
+
+251
+00:19:35,980 --> 00:19:41,040
+الجنف هو عامل زي حدوث الفرس أو زي سرج الحصان تمام؟
+
+252
+00:19:41,040 --> 00:19:48,400
+هذا بيسمحي بحركة برضه بيه أكتر من axis احنا بلاحظ
+
+253
+00:19:48,400 --> 00:19:51,840
+ان ال thumb flexion extension abduction abduction
+
+254
+00:19:51,840 --> 00:19:55,320
+وحاجة بنسميها opposition opposition يعني حركة
+
+255
+00:19:55,320 --> 00:19:58,460
+ديران اللي احنا حلقة التصبيح هذه يا جماعة إذا
+
+256
+00:19:58,460 --> 00:20:02,970
+انتوا يعني بتسبحواحركة السفيح هي عبارة عن
+
+257
+00:20:02,970 --> 00:20:08,670
+opposition of the metacarpophalangeal joint of the
+
+258
+00:20:08,670 --> 00:20:09,470
+thumb
+
+259
+00:20:15,620 --> 00:20:20,480
+هنا إذا إحنا شايفين في ال slide هذه الحركة ال
+
+260
+00:20:20,480 --> 00:20:25,020
+planner joins between the navicular and the second
+
+261
+00:20:25,020 --> 00:20:29,840
+and third uniform of the tarsal of the نجواب حد
+
+262
+00:20:29,840 --> 00:20:33,940
+الرسم أنه فيه مفاصل لكن الحركة فيهم بسيطة تصير
+
+263
+00:20:33,940 --> 00:20:37,040
+أثناء ال weight bearing و المشي
+
+264
+00:20:39,400 --> 00:20:43,580
+هيتكلمنا عن الـ Stability فإحنا بن .. يعني الرسم
+
+265
+00:20:43,580 --> 00:20:46,800
+التوضيحي اللي موجود وإحنا بنعرف قاعدة أساسية في
+
+266
+00:20:46,800 --> 00:20:49,040
+الـ Biomechanics إذا في حدا مننا درس الـ
+
+267
+00:20:49,040 --> 00:20:54,040
+Biomechanics إنه كل ما كان الجسم mobile أكتر كل ما
+
+268
+00:20:54,040 --> 00:20:58,540
+قلت بس الـ Stability بعنى إنه في تناسب عكسي بين ال
+
+269
+00:20:58,540 --> 00:21:04,380
+mobility و ال stability كل ما كان الجسم
+
+270
+00:21:05,590 --> 00:21:09,730
+أقل حركة أو حركته أقل فالكل ناكلة stability تبعته
+
+271
+00:21:09,730 --> 00:21:13,810
+أعلى فلتدرجنا بالمفاصل بنلاقي المفاصل في جسم
+
+272
+00:21:13,810 --> 00:21:18,130
+الإنسان بتبدأ من الأقل هم stability وأكثرهم
+
+273
+00:21:18,130 --> 00:21:22,470
+mobility هو shoulder joint لإن بنعمل 180 flexion
+
+274
+00:21:22,470 --> 00:21:28,550
+و180 abduction وبناخد حركة ال rotation بتوصل ل 90
+
+275
+00:21:30,140 --> 00:21:35,320
+فهو لسه stable و كمان شكل المفصل هو بيقلل يعني بي
+
+276
+00:21:35,320 --> 00:21:38,320
+.. يعني شكل المفصل نفسه أنه مافيش فيه congruency
+
+277
+00:21:38,320 --> 00:21:41,940
+كتير مافيش فيه تطابق كتير و بيحتاج لبادل كتير في
+
+278
+00:21:41,940 --> 00:21:47,280
+حاجة اسمهاLabrum حوالين الـGlenoid كبتي في الكبلة
+
+279
+00:21:47,280 --> 00:21:51,100
+بتساعد على ال congruence فهو أقل stable كمان ال
+
+280
+00:21:51,100 --> 00:21:55,260
+hip هو يعني ال stability اللي بيستمدها من كمية ال
+
+281
+00:21:55,260 --> 00:21:59,600
+ligaments اللي موجودة عليه لكن هو كمان less stable
+
+282
+00:21:59,600 --> 00:22:06,320
+جون القلبه بيتدرج هو بيروح ناحية ال stabilityأكتر
+
+283
+00:22:06,320 --> 00:22:10,700
+وقلنا ال amphetrosis joints زي ال intervertebral
+
+284
+00:22:10,700 --> 00:22:13,920
+اللي يسمى stable كمان أكتر هما الأكتر المستابلية
+
+285
+00:22:13,920 --> 00:22:16,380
+اللي هو الأقل هو movement اللي مافيش فيه movement
+
+286
+00:22:16,380 --> 00:22:20,260
+زي السوتشارب of the skull طب هل ايه ده ال type of
+
+287
+00:22:20,260 --> 00:22:25,670
+movement؟ ال type of movement هناانا شرحتها قبل
+
+288
+00:22:25,670 --> 00:22:28,390
+شويه وانا واقفة اقول ان في عندنا abduction و
+
+289
+00:22:28,390 --> 00:22:32,110
+abduction في عندنا dorsiflexion و plantar flexion
+
+290
+00:22:32,110 --> 00:22:37,270
+لما بنتكلم عن الفوت بنتكلم عن dorsal flexion اللي
+
+291
+00:22:37,270 --> 00:22:40,530
+هي flexion and extension plantar اللي انا بروح
+
+292
+00:22:40,530 --> 00:22:45,830
+برجل ناحية ال plantar surface of the foot وفي
+
+293
+00:22:45,830 --> 00:22:51,980
+عندنا flexion و extension و hyper extensionكمان في
+
+294
+00:22:51,980 --> 00:22:55,400
+عندنا ال rotation and circumduction وهو ده وضحنا
+
+295
+00:22:55,400 --> 00:23:01,820
+احنا لما كنا بنتكلم عن انواع المفاصل ال uniaxial و
+
+296
+00:23:01,820 --> 00:23:04,340
+ال multiaxial او ال biaxial
+
+297
+00:23:07,170 --> 00:23:09,950
+في عندنا حركة ال rotation و في عندنا ال
+
+298
+00:23:09,950 --> 00:23:13,590
+circumduction و في كمان حركة فيها supination و
+
+299
+00:23:13,590 --> 00:23:19,070
+antipronation هادية متمثلة بال radio ulnar joints
+
+300
+00:23:19,070 --> 00:23:24,670
+في عندنا حركات في الجهة هي عبارة عنالـ Eversion و
+
+301
+00:23:24,670 --> 00:23:25,650
+الـ Inversion هذه
+
+302
+00:23:25,650 --> 00:23:46,670
+بالفوتﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻ�
+
+303
+00:23:47,240 --> 00:23:50,320
+الـ head of the humerus and gluteal cavity اللي
+
+304
+00:23:50,320 --> 00:23:53,620
+موجودة في الـ scab اللي هو عبارة عن ball and
+
+305
+00:23:53,620 --> 00:23:58,300
+socket فيه كراء وفيه جيل هو loose joint capsule
+
+306
+00:23:58,300 --> 00:24:02,620
+عشان هيك في عنا هو mostly free joint أو freely
+
+307
+00:24:02,620 --> 00:24:06,640
+movable joint وفي عنا money per se عشان بتعمل
+
+308
+00:24:06,640 --> 00:24:13,260
+مخدات أو بتمنع الاحتكاك ما بين العضلات
+
+309
+00:24:13,260 --> 00:24:17,930
+اللي هي بتقوم بالحركة في هذا المكانوطبعا الـ
+
+310
+00:24:17,930 --> 00:24:22,250
+ligament طبيعي وظيفته انه يقلل من ال risk of
+
+311
+00:24:22,250 --> 00:24:25,770
+displacement ويمسك ال two ends of bones هدول في
+
+312
+00:24:25,770 --> 00:24:31,870
+المكان و هو طبعا very movable joint اما ال
+
+313
+00:24:31,870 --> 00:24:39,590
+shoulder command joint طبعا في عندنا حاجة ..
+
+314
+00:24:43,630 --> 00:24:49,590
+الـ shoulder joints هو عبارة محاط بالعديد من الـ
+
+315
+00:24:49,590 --> 00:24:54,070
+ligaments حتى تساعد على حماية هذا المفصل من
+
+316
+00:24:54,070 --> 00:24:57,590
+الزواغات وهو تقريبا من أكتر مفاصلة ممكن يكون معرض
+
+317
+00:24:57,590 --> 00:25:04,230
+لـ dislocation نتيجة حوادث الطرقممكن شد يعني ممكن
+
+318
+00:25:04,230 --> 00:25:06,950
+طفل صغير بس مجرد بنمسكه من أيدي و هيك نروح يحناخل
+
+319
+00:25:06,950 --> 00:25:09,650
+عينه و كتفه يحتاج إلى reduction و بنشوف أن
+
+320
+00:25:09,650 --> 00:25:13,790
+اللاعبين اللي مصارعه اتعرضوا كتير ل shoulder
+
+321
+00:25:13,790 --> 00:25:18,970
+dislocation لأن هو لسه stable joints و هو طبعا
+
+322
+00:25:18,970 --> 00:25:24,570
+محاطب عدد من ال ligament و ال bursite و غيرهأما ال
+
+323
+00:25:24,570 --> 00:25:32,970
+البوجوان فهو هلجو بتكون المفصل من الهيمرس الهيمرس
+
+324
+00:25:32,970 --> 00:25:37,930
+ال lower end of الهيمرس فيها لتروكليا و ال upper
+
+325
+00:25:37,930 --> 00:25:42,780
+end of الهيمرس فيها اسمها لتروكيلار نتشطبعا فيها
+
+326
+00:25:42,780 --> 00:25:45,780
+ان اخر مجموعات موجودة Gladial joint موجود بين
+
+327
+00:25:45,780 --> 00:25:50,080
+الـcapitulum المكان المخصص للـhead of radius على
+
+328
+00:25:50,080 --> 00:25:55,980
+الهيوميراس طبعا بيسمحني بالحركة في one axis في
+
+329
+00:25:55,980 --> 00:26:01,580
+سجنة لبنان around and خلّيني نقول frontal axis هي
+
+330
+00:26:01,580 --> 00:26:06,380
+reflection and extension و ملي reinforcing ملي
+
+331
+00:26:06,380 --> 00:26:09,920
+reinforcing لبنان وهو stable joints ليش stable
+
+332
+00:26:09,920 --> 00:26:14,150
+لأنه less movableهو مش استيابة لأن الحركة فيه
+
+333
+00:26:14,150 --> 00:26:17,830
+قليلة ومحاط بالعديد من ال الكميس وال articular
+
+334
+00:26:17,830 --> 00:26:25,460
+surfaces تبعته فيها congruenceطبعا هذا شكل الـ
+
+335
+00:26:25,460 --> 00:26:30,220
+elbow joints هو في عندنا هي الهيومراس وهي ال head
+
+336
+00:26:30,220 --> 00:26:34,180
+of radius وهي محاط في ال annular ligament عشان
+
+337
+00:26:34,180 --> 00:26:36,400
+يبقى ال head of larsen كتير من الأطفال لما نجيب
+
+338
+00:26:36,400 --> 00:26:38,720
+ونشدهم ونمسكهم من أيدهم بتلاقى بتطلع ال head of
+
+339
+00:26:38,720 --> 00:26:43,060
+radius من ال annular ligament وهذا بيعملهم ألم
+
+340
+00:26:43,060 --> 00:26:47,020
+بحتاج أنه نعملهم حركة خفيفة عشان نرجع المفصل وطبعا
+
+341
+00:26:47,020 --> 00:26:50,040
+على جانبي المفصل في عندنا radial collateral
+
+342
+00:26:50,040 --> 00:26:55,510
+ligamentوال .. و ال .. ال herculateral هي ما تلا
+
+343
+00:26:55,510 --> 00:26:58,730
+حماية هذا المفصل
+
+344
+00:27:00,880 --> 00:27:04,580
+أما الـ hip joints طبعا هذا من ال joints الكبيرة و
+
+345
+00:27:04,580 --> 00:27:07,860
+اللي بتتحمل wet bearing طبعا كتير و هو ball and
+
+346
+00:27:07,860 --> 00:27:12,480
+socket بتكون من ال head of humerus و الacetabulum
+
+347
+00:27:12,480 --> 00:27:17,000
+of coccyx اللي موجودة من ال .. ال pelvic bone هو
+
+348
+00:27:17,000 --> 00:27:21,320
+heavy joint capsule لأن هو بتحمل wet bearing كل
+
+349
+00:27:21,320 --> 00:27:25,540
+وزن الجسم بيكون محمل على ال two hips فعشان هيك
+
+350
+00:27:25,540 --> 00:27:30,600
+بتحتاج إلى الكثير من الحمايةطبعا ال reinforcement
+
+351
+00:27:30,600 --> 00:27:35,400
+بتجيل من ال ligament و طبعا ال freedom أقطت مش شدر
+
+352
+00:27:35,400 --> 00:27:38,940
+لكن هي movement in three blood يعني بيعمل flexion,
+
+353
+00:27:39,040 --> 00:27:42,100
+extension, hyperextension, abduction, adduction,
+
+354
+00:27:42,300 --> 00:27:43,820
+middle rotation, lateral rotation and
+
+355
+00:27:43,820 --> 00:27:44,720
+circumduction
+
+356
+00:27:46,880 --> 00:27:50,100
+حكينا ان هو بول انسكت فبقى طيلة movement in the
+
+357
+00:27:50,100 --> 00:27:53,080
+three plan طبعا في عنا عديد من ال ligaments احنا
+
+358
+00:27:53,080 --> 00:27:56,780
+عارفين ان ال head bones عبارة عن ال alien و ال
+
+359
+00:27:56,780 --> 00:28:00,500
+pupae و ال ischium ده ما احنا شايفين هنا فلازم انه
+
+360
+00:28:00,500 --> 00:28:06,030
+بيكون في عنا ligament بيربط الالفيمر مع هدال
+
+361
+00:28:06,030 --> 00:28:09,750
+العضلات وشوفين تفقه احنا هنا متشابكة ولجانب ان في
+
+362
+00:28:09,750 --> 00:28:13,970
+مكان كان موجود داخل من ال head نفسه الى ال
+
+363
+00:28:13,970 --> 00:28:18,190
+acetabulum هذا عامل زى كأنه زى مصمار كده بس هو رجع
+
+364
+00:28:18,190 --> 00:28:24,860
+منه طبعاموجود بيربط الـ head مع الـ acetabulum و
+
+365
+00:28:24,860 --> 00:28:30,980
+حوالينه في الاليوفميرال لجامنت و في الاسكيوفميرال
+
+366
+00:28:30,980 --> 00:28:35,340
+لجامنت و في البيوكوفميرال لجامنت و هدول لجامنت
+
+367
+00:28:35,340 --> 00:28:41,480
+قوية جدا في ال من هي dense tissue طبعا dense
+
+368
+00:28:41,480 --> 00:28:45,780
+fibrous tissue عشان انها تساعد في ال stabilityأما
+
+369
+00:28:45,780 --> 00:28:48,640
+ال V-zone تقولنا هو most complex zones و ال
+
+370
+00:28:48,640 --> 00:28:53,480
+largest zones of the body طبعا بيحمل وزن كمان أكتر
+
+371
+00:28:53,480 --> 00:28:56,520
+من الوزن اللي بيحمله ال head لإن هو بياخد وزن
+
+372
+00:28:56,520 --> 00:29:01,440
+الجسم كله الابدنى كله في عنا medial and lateral
+
+373
+00:29:01,440 --> 00:29:05,940
+condyle of the testes في مرض تلتحم ال medial و
+
+374
+00:29:05,940 --> 00:29:10,480
+lateral condyles of theproximal end of the tibia
+
+375
+00:29:10,480 --> 00:29:14,360
+,femur articulates anteriorly with العضمة السابونة
+
+376
+00:29:14,360 --> 00:29:18,420
+اللي نسميها البتلة اللي هي أساسها my bone,modified
+
+377
+00:29:18,420 --> 00:29:21,700
+hinge joint طبعا ليش modified لأنه بيسمح
+
+378
+00:29:21,700 --> 00:29:24,930
+بreflection extensionوالقليل من الـ rotation فيه
+
+379
+00:29:24,930 --> 00:29:28,310
+reflection position طبعا strengthened by manual
+
+380
+00:29:28,310 --> 00:29:32,810
+ligaments أنتمبال والمنسكاي اللي هي المنسكاي عبارة
+
+381
+00:29:32,810 --> 00:29:35,910
+عن المخدات الموجودة في المفصل عشان تساعد ال
+
+382
+00:29:35,910 --> 00:29:39,650
+congruence في المفصل وتساعد على ال stability و
+
+383
+00:29:39,650 --> 00:29:43,290
+manual corsage زي ما احنا شايفين عشان تسهل عملية
+
+384
+00:29:43,290 --> 00:29:48,270
+الحركة وهي ال movement طبعته بتكون في ال Sagittal
+
+385
+00:29:48,270 --> 00:29:53,110
+Planeطبعا ال complexity تزايا من عدد من ال
+
+386
+00:29:53,110 --> 00:29:56,750
+ligament اللي موجودة، في عندنا حاجة اسمها إكراشية
+
+387
+00:29:56,750 --> 00:29:59,350
+في ال ligament، في عندنا two meniscus medial and
+
+388
+00:29:59,350 --> 00:30:01,830
+lateral، في عندنا ال lateral collateral ligament،
+
+389
+00:30:01,830 --> 00:30:05,700
+في عندنا ال medial collateral ligamentوان
+
+390
+00:30:05,700 --> 00:30:09,500
+الفيبيولار طبعا الفيبيولار على ناحية الفيبيولا
+
+391
+00:30:09,500 --> 00:30:13,400
+بلاترالي والميديا ال collateral ligament هو على
+
+392
+00:30:13,400 --> 00:30:16,880
+التيبيا بسمي تيبيا ال collateral ligament هذه كلها
+
+393
+00:30:16,880 --> 00:30:22,280
+ال .. ال .. ال ligaments هتساعد على ال stability
+
+394
+00:30:22,280 --> 00:30:27,820
+of the knee joint وتسمح طبعا بالحركةالتغييرات اللي
+
+395
+00:30:27,820 --> 00:30:31,580
+بتصير joint stiffness دائما هي early sign of
+
+396
+00:30:31,580 --> 00:30:34,520
+ageing، بتبقى أنه ال flexibility تبعت الجوانت
+
+397
+00:30:34,520 --> 00:30:37,600
+تتقل، ال fibrous zones طبعا أول حاجة بتصير
+
+398
+00:30:37,600 --> 00:30:42,980
+strengthening لأنها بتقل المرونة تبعتها طبعا في ال
+
+399
+00:30:42,980 --> 00:30:46,630
+sympathiesالـ joint و الـ vertebral column كلها
+
+400
+00:30:46,630 --> 00:30:49,470
+بتصير diminished flexibility و decreased لأنه احنا
+
+401
+00:30:49,470 --> 00:30:53,710
+بنلاحظ أنه الشخص بيقسر كل مزاد في العمر طبعا عملية
+
+402
+00:30:53,710 --> 00:30:57,310
+الطول بتكون أثناء النمو بيثبت الطول بعدين في ال
+
+403
+00:30:57,310 --> 00:31:00,630
+aging بيقسر لأن الفراغ اللي مابين ال vertebral
+
+404
+00:31:00,630 --> 00:31:04,590
+column الفراغ اللي موجود بين المفاصل هذا بقل طبعا
+
+405
+00:31:04,590 --> 00:31:09,950
+بتقل spasticity تبع ال synovial joints و طبعا ليه؟
+
+406
+00:31:09,950 --> 00:31:16,520
+لأن ال blood supply بتقلالعمل والتجارب تساعد على
+
+407
+00:31:16,520 --> 00:31:24,060
+تحسين تبعة الجنس لفترة طويلة، أما الـcycle of life
+
+408
+00:31:24,060 --> 00:31:28,840
+للـarticulation في الـboneكمان بيصير ossification
+
+409
+00:31:28,840 --> 00:31:33,820
+between birth and skeletal maturity الفونتانيلز
+
+410
+00:31:33,820 --> 00:31:38,080
+اللى حكينا عنها في ال cranium بتروح بتصير VLTN
+
+411
+00:31:38,080 --> 00:31:41,820
+بيصير social zone زى ما احنا قدرنا و حكينا و ال
+
+412
+00:31:41,820 --> 00:31:44,760
+effusary plate خلاص بيصير ossified و بيصير no more
+
+413
+00:31:44,760 --> 00:31:51,260
+خليني نقول length لبنها بتعود تطول لعنضها سم معين
+
+414
+00:31:51,260 --> 00:31:55,680
+بيوقف نمو هذه العضام وما بيقول الشخص اللى بيطول
+
+415
+00:31:55,680 --> 00:32:00,020
+اكترمن هاك طبعا كل ما بيكبر ال range of motion
+
+416
+00:32:00,020 --> 00:32:04,880
+بتقل و ال gap بيصير فيه تغيرات ففي عامة كتير من ال
+
+417
+00:32:04,880 --> 00:32:10,900
+skeletal disease ممكن تأدي .. ممكن تكون من ال ..
+
+418
+00:32:10,900 --> 00:32:16,660
+تعمل abnormal growthوبتأثر على المفاصل وفي عندنا
+
+419
+00:32:16,660 --> 00:32:20,020
+بعض ال disease اللي بتكون specific with
+
+420
+00:32:20,020 --> 00:32:23,780
+development period من المشاكل اللي ممكن تصيب
+
+421
+00:32:23,780 --> 00:32:26,980
+العظام اللي هي ال sprain و ال bursitis و التذنعيس
+
+422
+00:32:26,980 --> 00:32:30,260
+ال sprains احنا ممكن ما زمنا في يوم من الأيام
+
+423
+00:32:30,260 --> 00:32:34,440
+تعرضنا للأكل sprain يعني بيصير في لوية الرجل هذه
+
+424
+00:32:34,440 --> 00:32:37,140
+damaged to the cartilage أو ligament أو tendon
+
+425
+00:32:37,140 --> 00:32:42,580
+associated withوطبعا هي عبارة عن حركة من ناحية
+
+426
+00:32:42,580 --> 00:32:47,060
+biomechanics فهي حركة إتلوائية بتصير في المفصل أما
+
+427
+00:32:47,060 --> 00:32:49,340
+ال borsitis احنا كنا نتعرف على ال borsa اللي
+
+428
+00:32:49,340 --> 00:32:53,020
+موجودة عشان نتسهل حركة المفاصل فيمكن يصير فيها
+
+429
+00:32:53,020 --> 00:32:58,020
+inflammation و عادة ما بتصير هذه إلا من ال overuse
+
+430
+00:32:58,020 --> 00:33:02,460
+للجوانب ال tendonitis هي عبارة عن inflammation في
+
+431
+00:33:02,460 --> 00:33:08,500
+ال tendon ممكن تصير نتيجة ال exercise المتكرر
+
+432
+00:33:10,200 --> 00:33:13,660
+الarthritis من المشاكل اللي ممكن نتعرض إليها مع ال
+
+433
+00:33:13,660 --> 00:33:18,480
+aging أو إذا صار فيه ضربة مباشرة على المفصل هي
+
+434
+00:33:18,480 --> 00:33:21,600
+inflammatory or degenerative disease of the joints
+
+435
+00:33:21,600 --> 00:33:26,920
+بتظهر الألم و ال stiffness و ال swelling في ال
+
+436
+00:33:26,920 --> 00:33:33,590
+joints أما اليعني هذه طبعا ال .. ال .. من الأشياء
+
+437
+00:33:33,590 --> 00:33:36,610
+اللي ممكن أنها تحصل زي الـ Gouty Arthritis الناس
+
+438
+00:33:36,610 --> 00:33:40,050
+اللي بيقولك هنده نقرص بينتج عن الأكل اللحوم ال ..
+
+439
+00:33:40,050 --> 00:33:45,630
+ال .. الكتيرة و ال osteoarthritis اللي بتصير أنه
+
+440
+00:33:45,630 --> 00:33:50,050
+التهيبات في ال cartilage و تأكل في ال cartilage
+
+441
+00:33:51,440 --> 00:33:53,900
+بيأدى لـDegrees لـRange of Motion أما
+
+442
+00:33:53,900 --> 00:33:55,660
+الـRheumatoid Arthritis فهذا System Disease
+
+443
+00:33:55,660 --> 00:33:58,600
+Inflammatory Inflammation of the joint result in
+
+444
+00:33:58,600 --> 00:34:02,140
+an autoimmune disease فهو هذا System Disease بيأثر
+
+445
+00:34:02,140 --> 00:34:08,340
+على المفاصل وهذه تقريبا الصورة لبعد المفاصل اللى
+
+446
+00:34:08,340 --> 00:34:11,950
+ممكن تكونيعني الفرق بين ال normal joints و بين ال
+
+447
+00:34:11,950 --> 00:34:16,190
+osteoarthritic joints فاحنا في نهاية محاضرتنا
+
+448
+00:34:16,190 --> 00:34:19,710
+لليوم احنا اتكلمنا فيها عن ال articulations او ال
+
+449
+00:34:19,710 --> 00:34:22,750
+joints of the .. of the body و قلنا اتعرفنا على
+
+450
+00:34:22,750 --> 00:34:27,830
+أهميتها و كمان على أنواعها و عرفنا الفرق بين ال ..
+
+451
+00:34:27,830 --> 00:34:31,930
+ال uniaxial و ال biaxial و ال multiaxial joints و
+
+452
+00:34:31,930 --> 00:34:36,150
+عرفنا انهأهم شيء أنه ال .. ال .. ال .. ال ..
+
+453
+00:34:36,150 --> 00:34:40,530
+التناسب العكسي ما بين ال mobility and stability of
+
+454
+00:34:40,530 --> 00:34:43,710
+the joints و ان شاء الله في المحاضرة القادمة هيكون
+
+455
+00:34:43,710 --> 00:34:46,390
+موضوعنا عن ال nervous system لكم ان شاء الله في
+
+456
+00:34:46,390 --> 00:34:47,250
+المحاضرة القادمة
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..8babe32b4b294a2183a1b8d10684ec0cdeabacf9
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 2212, "start": 4.94, "end": 22.12, "text": "بسم الله الرحمن الرحيم و الصلاة والسلام على سيدنا محمد سيد المرسلين، اليوم محاضرتنا استكمال لل skeletal system، في جزء مهم في ال skeletal system، لازم نتعرف عليه، هو ال joints or ال articulations", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 4032, 31767, 15040, 3660, 16070, 3794, 37440, 15844, 8608, 25708, 8315, 3714, 35571, 3215, 8608, 25708, 9673, 2288, 3794, 1211, 9957, 12399, 45595, 20498, 3714, 5016, 46958, 43500, 8315, 44713, 24793, 6027, 24976, 32321, 304, 1185, 12399, 8978, 10874, 11622, 38207, 3714, 16095, 8978, 2423, 32321, 304, 1185, 12399, 5296, 31377, 2304, 8717, 2655, 3615, 28480, 47356, 12399, 31439, 2423, 19949, 420, 2423, 15228, 4136], "avg_logprob": -0.13447916507720947, "compression_ratio": 1.6210526315789473, "no_speech_prob": 3.5762786865234375e-07, "words": [{"start": 4.94, "end": 5.28, "word": "بسم", "probability": 0.899658203125}, {"start": 5.28, "end": 5.4, 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{"start": 89.58, "end": 91.6, "word": " المفصل", "probability": 0.9645182291666666}, {"start": 91.6, "end": 91.8, "word": " في", "probability": 0.94677734375}, {"start": 91.8, "end": 92.3, "word": " عندنا", "probability": 0.810791015625}, {"start": 92.3, "end": 92.62, "word": " في", "probability": 0.68994140625}, {"start": 92.62, "end": 92.76, "word": " ال", "probability": 0.9560546875}, {"start": 92.76, "end": 93.38, "word": " epiphysis", "probability": 0.6593424479166666}, {"start": 93.38, "end": 93.62, "word": " في", "probability": 0.75830078125}, {"start": 93.62, "end": 93.84, "word": " عندنا", "probability": 0.969482421875}, {"start": 93.84, "end": 95.28, "word": " الepiphysial", "probability": 0.599267578125}, {"start": 95.28, "end": 95.62, "word": " growth", "probability": 0.79248046875}, {"start": 95.62, "end": 96.04, "word": " فكان", "probability": 0.93310546875}, {"start": 96.04, "end": 96.3, "word": " في", "probability": 0.95849609375}, {"start": 96.3, "end": 97.14, "word": 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"end": 1148.87, "word": " Axis", "probability": 0.741455078125}, {"start": 1148.87, "end": 1149.07, "word": " اللي", "probability": 0.976318359375}, {"start": 1149.07, "end": 1149.67, "word": " هما", "probability": 0.7091064453125}, {"start": 1149.67, "end": 1149.95, "word": " ال", "probability": 0.85595703125}, {"start": 1149.95, "end": 1150.29, "word": " first", "probability": 0.5361328125}, {"start": 1150.29, "end": 1150.69, "word": " and", "probability": 0.9267578125}, {"start": 1150.69, "end": 1151.07, "word": " second", "probability": 0.9326171875}, {"start": 1151.07, "end": 1151.73, "word": " cervical", "probability": 0.92822265625}, {"start": 1151.73, "end": 1152.51, "word": " vertebra", "probability": 0.900390625}, {"start": 1152.51, "end": 1152.99, "word": " فقولنا", "probability": 0.8050130208333334}], "temperature": 1.0}, {"id": 54, "seek": 117460, "start": 1153.29, "end": 1174.61, "text": "الـ Axis فيه إلها الـ Odontoid process فيه هي process موجود في الفتحة أو في الفرمن في ال Axis لأن هما كانت إشكالهم كانت مختلفة إذا بتذكروا وإنها بتسمح بحركة ال rotation هذه بتشكل pivot joint", "tokens": [6027, 39184, 20118, 271, 8978, 3224, 11933, 1211, 11296, 2423, 39184, 12210, 7556, 327, 1399, 8978, 3224, 39896, 1399, 3714, 29245, 23328, 8978, 27188, 2655, 5016, 3660, 34051, 8978, 27188, 2288, 27842, 8978, 2423, 20118, 271, 5296, 33456, 8032, 15042, 25961, 2655, 11933, 8592, 4117, 6027, 16095, 25961, 2655, 3714, 46456, 46538, 3660, 11933, 15730, 39894, 8848, 37983, 14407, 4032, 28814, 1863, 11296, 39894, 38251, 5016, 4724, 5016, 31747, 3660, 2423, 12447, 29538, 39894, 8592, 28820, 14538, 7225], "avg_logprob": -0.30577531570120703, "compression_ratio": 1.596774193548387, "no_speech_prob": 1.7881393432617188e-07, "words": [{"start": 1153.29, "end": 1154.09, "word": "الـ", "probability": 0.767822265625}, {"start": 1154.09, "end": 1155.45, "word": " Axis", "probability": 0.55926513671875}, {"start": 1155.45, "end": 1155.77, "word": " فيه", "probability": 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flexion extension abduction abduction وحاجة بنسميها opposition opposition يعني حركة ديران اللي احنا حلقة التصبيح هذه يا جماعة إذا انتوا يعني بتسبحوا", "tokens": [10721, 15042, 21136, 3215, 25724, 1863, 5172, 31439, 6225, 10943, 1211, 30767, 1829, 11331, 3215, 2407, 12984, 27188, 2288, 3794, 34051, 30767, 1829, 8608, 47341, 21542, 9381, 7649, 46811, 10943, 22807, 23758, 4724, 1829, 38251, 5016, 1829, 4724, 5016, 31747, 3660, 4724, 43042, 3224, 4724, 1829, 3224, 5551, 4117, 2655, 2288, 9154, 10298, 1975, 5016, 8315, 4724, 15040, 5016, 19913, 16472, 2423, 9298, 5896, 313, 10320, 410, 40335, 410, 40335, 4032, 5016, 26108, 3660, 44945, 38251, 1829, 11296, 13504, 13504, 37495, 22653, 11331, 31747, 3660, 11778, 13546, 7649, 13672, 1829, 1975, 5016, 8315, 11331, 1211, 28671, 16712, 9381, 21292, 5016, 29538, 35186, 10874, 15042, 27884, 11933, 15730, 16472, 2655, 14407, 37495, 22653, 39894, 35457, 5016, 14407], "avg_logprob": -0.2347756400067582, "compression_ratio": 1.699604743083004, 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"word": " ان", "probability": 0.67138671875}, {"start": 1188.58, "end": 1188.74, "word": " ال", "probability": 0.212890625}, {"start": 1188.74, "end": 1188.98, "word": " thumb", "probability": 0.203857421875}, {"start": 1188.98, "end": 1189.86, "word": " flexion", "probability": 0.793212890625}, {"start": 1189.86, "end": 1190.46, "word": " extension", "probability": 0.8427734375}, {"start": 1190.46, "end": 1191.3, "word": " abduction", "probability": 0.7047119140625}, {"start": 1191.3, "end": 1191.84, "word": " abduction", "probability": 0.686767578125}, {"start": 1191.84, "end": 1192.22, "word": " وحاجة", "probability": 0.8868408203125}, {"start": 1192.22, "end": 1192.76, "word": " بنسميها", "probability": 0.8721923828125}, {"start": 1192.76, "end": 1193.5, "word": " opposition", "probability": 0.94287109375}, {"start": 1193.5, "end": 1194.48, "word": " opposition", "probability": 0.92578125}, {"start": 1194.48, "end": 1194.86, "word": " يعني", "probability": 0.965087890625}, {"start": 1194.86, "end": 1195.32, "word": " حركة", "probability": 0.9939778645833334}, {"start": 1195.32, "end": 1195.96, "word": " ديران", "probability": 0.79736328125}, {"start": 1195.96, "end": 1196.3, "word": " اللي", "probability": 0.7313232421875}, {"start": 1196.3, "end": 1196.42, "word": " احنا", "probability": 0.9482421875}, {"start": 1196.42, "end": 1196.8, "word": " حلقة", "probability": 0.8712565104166666}, {"start": 1196.8, "end": 1197.46, "word": " التصبيح", "probability": 0.951171875}, {"start": 1197.46, "end": 1197.78, "word": " هذه", "probability": 0.673828125}, {"start": 1197.78, "end": 1197.98, "word": " يا", "probability": 0.7626953125}, {"start": 1197.98, "end": 1198.22, "word": " جماعة", "probability": 0.9959309895833334}, {"start": 1198.22, "end": 1198.46, "word": " إذا", "probability": 0.86279296875}, {"start": 1198.46, "end": 1199.12, "word": " انتوا", "probability": 0.747802734375}, {"start": 1199.12, "end": 1199.42, "word": " يعني", "probability": 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13412, 16606, 21984, 8978, 9673, 5016, 46958, 25720, 25062, 18513, 46007], "avg_logprob": -0.14187046496764474, "compression_ratio": 1.747191011235955, "no_speech_prob": 1.1920928955078125e-07, "words": [{"start": 2073.11, "end": 2073.49, "word": "أهم", "probability": 0.849853515625}, {"start": 2073.49, "end": 2073.91, "word": " شيء", "probability": 0.70068359375}, {"start": 2073.91, "end": 2074.33, "word": " أنه", "probability": 0.75341796875}, {"start": 2074.33, "end": 2074.67, "word": " ال", "probability": 0.7109375}, {"start": 2074.67, "end": 2074.91, "word": " ..", "probability": 0.9638671875}, {"start": 2074.91, "end": 2075.35, "word": " ال", "probability": 0.93115234375}, {"start": 2075.35, "end": 2075.35, "word": " ..", "probability": 0.98583984375}, {"start": 2075.35, "end": 2075.89, "word": " ال", "probability": 0.8896484375}, {"start": 2075.89, "end": 2076.13, "word": " ..", "probability": 0.95068359375}, {"start": 2076.13, "end": 2076.13, "word": " ال", "probability": 0.53662109375}, {"start": 2076.13, "end": 2076.15, "word": " ..", "probability": 0.841796875}, {"start": 2076.15, "end": 2077.15, "word": " التناسب", "probability": 0.8642578125}, {"start": 2077.15, "end": 2077.65, "word": " العكسي", "probability": 0.9755859375}, {"start": 2077.65, "end": 2077.81, "word": " ما", "probability": 0.94970703125}, {"start": 2077.81, "end": 2078.11, "word": " بين", "probability": 0.990234375}, {"start": 2078.11, "end": 2078.61, "word": " ال", "probability": 0.7568359375}, {"start": 2078.61, "end": 2079.05, "word": " mobility", "probability": 0.9619140625}, {"start": 2079.05, "end": 2079.49, "word": " and", "probability": 0.9580078125}, {"start": 2079.49, "end": 2080.13, "word": " stability", "probability": 0.826171875}, {"start": 2080.13, "end": 2080.53, "word": " of", "probability": 0.9892578125}, {"start": 2080.53, "end": 2080.83, "word": " the", "probability": 0.93310546875}, {"start": 2080.83, "end": 2081.31, "word": " joints", "probability": 0.3662109375}, {"start": 2081.31, "end": 2081.77, "word": " و", "probability": 0.9560546875}, {"start": 2081.77, "end": 2081.85, "word": " ان", "probability": 0.5361328125}, {"start": 2081.85, "end": 2081.99, "word": " شاء", "probability": 0.98974609375}, {"start": 2081.99, "end": 2082.11, "word": " الله", "probability": 0.94970703125}, {"start": 2082.11, "end": 2082.25, "word": " في", "probability": 0.85009765625}, {"start": 2082.25, "end": 2082.69, "word": " المحاضرة", "probability": 0.931640625}, {"start": 2082.69, "end": 2083.13, "word": " القادمة", "probability": 0.9930013020833334}, {"start": 2083.13, "end": 2083.71, "word": " هيكون", "probability": 0.931884765625}, {"start": 2083.71, "end": 2084.29, "word": " موضوعنا", "probability": 0.96259765625}, {"start": 2084.29, "end": 2084.49, "word": " عن", "probability": 0.99462890625}, {"start": 2084.49, "end": 2084.61, "word": " ال", "probability": 0.78955078125}, {"start": 2084.61, "end": 2084.95, "word": " nervous", "probability": 0.8173828125}, {"start": 2084.95, "end": 2085.47, "word": " system", "probability": 0.96630859375}, {"start": 2085.47, "end": 2085.85, "word": " لكم", "probability": 0.559326171875}, {"start": 2085.85, "end": 2085.97, "word": " ان", "probability": 0.5185546875}, {"start": 2085.97, "end": 2086.15, "word": " شاء", "probability": 0.995849609375}, {"start": 2086.15, "end": 2086.25, "word": " الله", "probability": 0.96044921875}, {"start": 2086.25, "end": 2086.39, "word": " في", "probability": 0.97607421875}, {"start": 2086.39, "end": 2086.81, "word": " المحاضرة", "probability": 0.99560546875}, {"start": 2086.81, "end": 2087.25, "word": " القادمة", "probability": 0.9944661458333334}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2087.6596875, "duration_after_vad": 2032.8937499999963}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..c98c27317d1de524afc231e4865ff94482c694e6
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/r7JqcTLD7pY_raw.srt
@@ -0,0 +1,1836 @@
+1
+00:00:04,940 --> 00:00:08,860
+بسم الله الرحمن الرحيم و الصلاة والسلام على سيدنا
+
+2
+00:00:08,860 --> 00:00:12,600
+محمد سيد المرسلين، اليوم محاضرتنا استكمال لل
+
+3
+00:00:12,600 --> 00:00:17,120
+skeletal system، في جزء مهم في ال skeletal system،
+
+4
+00:00:17,120 --> 00:00:22,120
+لازم نتعرف عليه، هو ال joints or ال articulations
+
+5
+00:00:22,610 --> 00:00:27,030
+طبعا أش وظيفة ال joints هي بترتبط بين two adjacent
+
+6
+00:00:27,030 --> 00:00:31,250
+و تعريف ال joints يعني اللي هو ال wrap between two
+
+7
+00:00:31,250 --> 00:00:37,070
+adjacent bone يعني عضمة يان يكونوا بشكل مفصل عن
+
+8
+00:00:37,070 --> 00:00:42,010
+طريقالتحام هم و طبعا الاتحام هذا بيكون حسب شكل
+
+9
+00:00:42,010 --> 00:00:46,450
+المفصل بتعطينا نوع الحركة، يبقى أول حاجة ال joints
+
+10
+00:00:46,450 --> 00:00:49,350
+هي اللي بتربط العضام مع بعضها و بتخلينا احنا
+
+11
+00:00:49,350 --> 00:00:53,450
+واقفين هيك، احنا لو ماكنش في عندنا joints فبيكون
+
+12
+00:00:53,450 --> 00:00:56,750
+احنا بنشتغل زي ال robot مافيش امكانية ان احنا لا
+
+13
+00:00:56,750 --> 00:00:59,970
+نتنقض ايدينا ولا نتنقض أجلينا ولا نتحرك، هتحرك
+
+14
+00:00:59,970 --> 00:01:06,460
+بصورة خلنا نقول متصلبةفال .. يبقى ال articulations
+
+15
+00:01:06,460 --> 00:01:14,120
+بتساعدني على الحركة و كمانبتساعد على النمو كيف لو
+
+16
+00:01:14,120 --> 00:01:18,600
+احنا نولدنا بنفس الحجم هذا فكان طبعا مستحيل عملية
+
+17
+00:01:18,600 --> 00:01:21,040
+الحمل و الولادة هذا تصير فعشان هيك احنا ولدنا
+
+18
+00:01:21,040 --> 00:01:25,880
+باحجام صغيرة و كان لازم عملية النمو طبيعي هاد تكون
+
+19
+00:01:25,880 --> 00:01:31,600
+فعشان هيك كان في نهاية العضمة قبل ما يبدأ المفصل
+
+20
+00:01:31,600 --> 00:01:35,280
+في عندنا في ال epiphysis في عندنا الepiphysial
+
+21
+00:01:35,280 --> 00:01:43,290
+growth فكان في عملية النمو للعظامكمان بتساعدنا على
+
+22
+00:01:43,290 --> 00:01:51,230
+التغيير الشكل العظام أثناء النمو وكمان بتساعد على
+
+23
+00:01:51,230 --> 00:01:55,430
+ال movement من خلال ال articulations من خلال
+
+24
+00:01:55,430 --> 00:01:58,990
+العضلات اللي بتكون حوالين المنفع الصلمي
+
+25
+00:02:03,070 --> 00:02:06,350
+كيف احنا سمينا هذه الإضاءة أو كيف العلماء سموا
+
+26
+00:02:06,350 --> 00:02:14,410
+هدولة الإضاءة؟ طبعا الاسم دايما derived من ال
+
+27
+00:02:14,410 --> 00:02:19,230
+articulations bone يعني ال tibia مع ال femur
+
+28
+00:02:19,230 --> 00:02:24,570
+هتعطيني ال knee ال humerus and ulnar مع ال radius
+
+29
+00:02:24,570 --> 00:02:31,090
+هتعطيني ال elbowو هكذا اللي قدها حسب ترتيبها هتكون
+
+30
+00:02:31,090 --> 00:02:35,630
+أسماء ال articulations حتى و كمان أنواعها اللي
+
+31
+00:02:35,630 --> 00:02:40,570
+بتعتمد على shape of the articular surfaces طبعا
+
+32
+00:02:40,570 --> 00:02:41,910
+تقسيمتها
+
+33
+00:02:44,110 --> 00:02:51,330
+يتقسمت بصراحة حسب الحركة وحسب شكل المفصل نروح ل ال
+
+34
+00:02:51,330 --> 00:02:57,550
+fibrous joints هي عبارة عن dense connective tissue
+
+35
+00:02:57,550 --> 00:03:04,650
+تجمع ال bones togetherالـ bones بيكون متلاسقة جدا
+
+36
+00:03:04,650 --> 00:03:08,090
+يعني بيكون فش فراغات بين ال bone يعني فش real
+
+37
+00:03:08,090 --> 00:03:13,270
+articulation الحقيقة two bones adjacent مرتبطين مع
+
+38
+00:03:13,270 --> 00:03:18,070
+بعضهم لكن فش كتير منها movement أما ال
+
+39
+00:03:18,070 --> 00:03:22,750
+cartilaginousفهي عبارة عن يالين كارتيلاج وفيبرو
+
+40
+00:03:22,750 --> 00:03:26,250
+كارتيلاج connected bone في هذا الشكل يعني خلنا
+
+41
+00:03:26,250 --> 00:03:29,430
+نقول ال fibers نكون في عضمتين جانب بعض احنا الحركة
+
+42
+00:03:29,430 --> 00:03:33,630
+فيهم مش ضرورية لكن لازم يكون في خلينا نقول
+
+43
+00:03:33,630 --> 00:03:38,110
+الالتصاق تبع العضمات أو ال stability تبع العضمتين
+
+44
+00:03:38,110 --> 00:03:43,160
+مع بعض الكارتيلاج لأ بتختلف شوية انهفي عندنا
+
+45
+00:03:43,160 --> 00:03:47,360
+التقام للعضلات لكن مش مباشر في عندنا cartilage او
+
+46
+00:03:47,360 --> 00:03:53,660
+fibrocartilage او او disk او اذا نقول ال disk في
+
+47
+00:03:53,660 --> 00:03:56,180
+عندنا الaneously process وفي عندنا ال nucleus اللي
+
+48
+00:03:56,180 --> 00:04:00,940
+هي بتساعد على ال fabrication لل joints و بتساعد
+
+49
+00:04:00,940 --> 00:04:04,500
+على الحركة البسيطة اما ال synivial joints وهذه ال
+
+50
+00:04:04,500 --> 00:04:06,900
+joints الكبيرة اللي موجودة المفاصلة الكبيرة زي ال
+
+51
+00:04:06,900 --> 00:04:11,220
+elbow و الhipهدولة بيكون أول حاجة ال complex لإن
+
+52
+00:04:11,220 --> 00:04:13,520
+تركيبها وال articular shared surface والسينوبيا
+
+53
+00:04:13,520 --> 00:04:17,060
+الفلود وال ligaments جوا وال ligaments برا و بتكون
+
+54
+00:04:17,060 --> 00:04:20,680
+محاطة بالسينوبيا ال membrane و هكذا هذه هي الإضام
+
+55
+00:04:20,680 --> 00:04:24,740
+اللي احنا بتساعد على الحركة الكبيرة اللي احنا
+
+56
+00:04:24,740 --> 00:04:28,580
+بنتحركها سواء في الambulation أو ال locomotion أو
+
+57
+00:04:28,580 --> 00:04:34,660
+في المصول للأشياءالانواع لو .. لو اجينا اتكلمنا
+
+58
+00:04:34,660 --> 00:04:39,560
+على ال .. يعني صنفوناها according to the movement
+
+59
+00:04:39,560 --> 00:04:42,960
+فبنلاقي أنه إلها تصنيفة تانية هي ال scene
+
+60
+00:04:42,960 --> 00:04:47,120
+arthrosis ال immovable bone و ال amphiarthrosis ال
+
+61
+00:04:47,120 --> 00:04:50,300
+slightly movable joint و ال diathrosis اللي هي زي
+
+62
+00:04:50,300 --> 00:04:54,800
+ال synovial joints فهي freely movable joints
+
+63
+00:04:57,100 --> 00:05:00,600
+ناخد أنواع أو أشكال الـfibrous genes هنلاقيها
+
+64
+00:05:00,600 --> 00:05:04,940
+three type بيسموها الـsyndesmosis والسوشر
+
+65
+00:05:04,940 --> 00:05:09,680
+والكمفوزس طيب إيش الفرق ما بينهم؟ الـsyndesmosis
+
+66
+00:05:09,680 --> 00:05:14,080
+فهو عبارة عن sheet between two bones زي ما إحنا
+
+67
+00:05:14,080 --> 00:05:20,020
+شايفين في الصورة اللي على اليمين هنا أو على يسار
+
+68
+00:05:20,020 --> 00:05:25,260
+الصورةانه فيه ان الـ tibia and fibula موجود في
+
+69
+00:05:25,260 --> 00:05:28,600
+بينهم كده غشاء، الغشاء هذا رابط هدول العدمتين عشان
+
+70
+00:05:28,600 --> 00:05:32,400
+يكونوا أكتر stability، هم العدمتين مرتبطين من تحت
+
+71
+00:05:32,400 --> 00:05:37,380
+المفصل و من فوق المفصل، المفصلين هدول مش متحركين،
+
+72
+00:05:37,380 --> 00:05:43,010
+تمام؟ف sheet or bundle of fibrous tissue connect
+
+73
+00:05:43,010 --> 00:05:46,570
+the bone هنا أما في أثرات يعني slightly movable
+
+74
+00:05:46,570 --> 00:05:49,910
+joints مابتتحركش كتير يعني هي بتسمح بالحركة
+
+75
+00:05:49,910 --> 00:05:55,210
+القليلة جدا ودايما يعني أكتر مثل نضرب عليها اللي
+
+76
+00:05:55,210 --> 00:05:59,810
+هو ال joints between tibia and fibulaالـ suture
+
+77
+00:05:59,810 --> 00:06:04,350
+طبعا احنا كلنا بنعرف انه الـ skull مجموعة من الـ
+
+78
+00:06:04,350 --> 00:06:07,590
+bones زي ما اتكلمنا فيه عينة frontal و parietal و
+
+79
+00:06:07,590 --> 00:06:11,150
+temporal و occipital هدولة بيشكلوا الـ skull ولا
+
+80
+00:06:11,150 --> 00:06:15,090
+في الأول في بينهم فيه foramen تمام؟ حالتا لما
+
+81
+00:06:15,090 --> 00:06:18,790
+بيتحم هذا ال foramen بيصير على شكل suture زي اللي
+
+82
+00:06:18,790 --> 00:06:23,290
+احنا شايفينها بالرسم كأنه مخيطة خياطة هذه خياطة
+
+83
+00:06:23,290 --> 00:06:27,560
+ربانيةهي تربط يبقى الـ suture تربط between the
+
+84
+00:06:27,560 --> 00:06:31,660
+flat bone وهي sinarthrosis، sinarthrosis يعني إنها
+
+85
+00:06:31,660 --> 00:06:35,640
+innovable joints، thin layer of connective tissue
+
+86
+00:06:35,640 --> 00:06:38,600
+connect the bone وزي ما احنا شايفناه، أما
+
+87
+00:06:38,600 --> 00:06:46,200
+الجنفاصيز يوز هي عبارة عن غذر تبع ال teethهي cone
+
+88
+00:06:46,200 --> 00:06:50,940
+-shaped bone process in a socket يعني في جيب شكل
+
+89
+00:06:50,940 --> 00:06:56,320
+مخلوطي عبنة مخلوطية الشكل مزروعة وين مزروعة في
+
+90
+00:06:56,320 --> 00:07:01,200
+مكان معين في جيب معين زي ال tooth in the jawbone
+
+91
+00:07:01,200 --> 00:07:04,920
+طبعا احنا بنعرف ان كل سن في الجذر الجذر هذا موجود
+
+92
+00:07:04,920 --> 00:07:08,780
+في اللثةوهذه sinarthrosis يعني تخيلنا أنها لو انها
+
+93
+00:07:08,780 --> 00:07:12,200
+movable كان احنا عمرنا ما عرفنا نمضغ او ناكل يبقى
+
+94
+00:07:12,200 --> 00:07:16,900
+السنان مثبتة و احنا بنرى لو هذا المفصل صار يعني
+
+95
+00:07:16,900 --> 00:07:22,360
+متراخ شوية بيعني القلم الجدير بيقدي نخلع هذا السن
+
+96
+00:07:22,360 --> 00:07:28,100
+فهي sinarthrosis no means no movement زي هذا الشكل
+
+97
+00:07:28,100 --> 00:07:34,080
+اللي احنا شايفه جدر السنأما ال cartilaginous فهي
+
+98
+00:07:34,080 --> 00:07:39,500
+synchondrosis مش متحركة زي ال .. ال .. ال .. ال ..
+
+99
+00:07:39,500 --> 00:07:42,800
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+100
+00:07:42,800 --> 00:07:43,740
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+101
+00:07:43,740 --> 00:07:43,780
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+102
+00:07:43,780 --> 00:07:45,800
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+103
+00:07:45,800 --> 00:07:45,860
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+104
+00:07:45,860 --> 00:07:46,700
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+105
+00:07:46,700 --> 00:07:46,760
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+106
+00:07:46,760 --> 00:07:46,840
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+107
+00:07:46,840 --> 00:07:46,840
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+108
+00:07:46,840 --> 00:07:46,840
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+109
+00:07:46,840 --> 00:07:46,840
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+110
+00:07:46,840 --> 00:07:54,010
+.. ال .. ال .. اليبقى synchondrosis bone of
+
+111
+00:07:54,010 --> 00:07:56,870
+yelling cartilage you need that bone يعني احنا
+
+112
+00:07:56,870 --> 00:08:00,830
+بلاقي كل rib في نهايتها زي ما احنا شايفين في عندنا
+
+113
+00:08:00,830 --> 00:08:03,750
+cartilage بتسميه costal cartilage بيعمل
+
+114
+00:08:03,750 --> 00:08:06,610
+attachments مع الاستيرنام
+
+115
+00:08:07,990 --> 00:08:11,750
+في الانفيزيا للبلاد طبعا هذا البلاد اللى بيسمح
+
+116
+00:08:11,750 --> 00:08:16,290
+بعملية انمو عساس انه كل ما بنكبر كل ما بيكبر هذا
+
+117
+00:08:16,290 --> 00:08:22,130
+بيصير ossification و بيساعد على طول العظام كمان
+
+118
+00:08:22,130 --> 00:08:29,090
+هدولة seen arthrosis يعني غير متحركة or immovable
+
+119
+00:08:31,330 --> 00:08:34,730
+أما الـ Synthesis هذا النوع التاني فهي Ibad-O
+
+120
+00:08:34,730 --> 00:08:37,830
+-Fibrocartilage between the bone شوفناها في
+
+121
+00:08:37,830 --> 00:08:41,130
+المحاضرة اللي فاتت في ال Pupic Synthesis اللي
+
+122
+00:08:41,130 --> 00:08:47,610
+بيعمل LTA blood to pupic bone في البلفكبونjoints
+
+123
+00:08:47,610 --> 00:08:50,710
+between bodies of adjacent vertebrae قولنا each
+
+124
+00:08:50,710 --> 00:08:55,210
+vertebra between two adjacent vertebra في عندنا ال
+
+125
+00:08:55,210 --> 00:08:59,030
+intervertebral دسكي موضح بالرسم وهو دي لأ
+
+126
+00:08:59,030 --> 00:09:03,250
+amphiarthrosis means انه slightly movable joints
+
+127
+00:09:03,250 --> 00:09:04,830
+عشان تسمح بالحركة
+
+128
+00:09:07,150 --> 00:09:10,790
+أما الـ Synovial فهو الـ most complicated joints
+
+129
+00:09:10,790 --> 00:09:16,710
+هي منتشرة على معظم مفاصل الجسم اللي فيها real
+
+130
+00:09:16,710 --> 00:09:21,190
+movement a basic feature أول حاجة أنها بتحتوي على
+
+131
+00:09:21,190 --> 00:09:27,670
+articular capsule في جيب كده أو شاق محيط بالمفصل
+
+132
+00:09:28,410 --> 00:09:33,450
+أيضًا فيها سينوفيول كافتي تبقى full of سينوفيول
+
+133
+00:09:33,450 --> 00:09:37,090
+fluid عشان يساعد على تغذية ال cartilage ويساعد
+
+134
+00:09:37,090 --> 00:09:40,510
+كمان على ال movement ويعمل نوع من ال lubricant
+
+135
+00:09:40,510 --> 00:09:44,550
+inside the joints فيعنى ال article ال cartilage
+
+136
+00:09:44,550 --> 00:09:48,830
+اللي هو covering ال heads أو خليني أقول ال
+
+137
+00:09:48,830 --> 00:09:53,550
+epiphysisال contact bone مع ال other bone لازم
+
+138
+00:09:53,550 --> 00:09:58,530
+تكون مادة نسقولة جدا مثل ال cartilage و نعمة أي
+
+139
+00:09:58,530 --> 00:10:01,990
+خشونة في هذه ال .. في هذا ال cartilage ممكن يؤدي
+
+140
+00:10:01,990 --> 00:10:05,990
+إلى .. إلى pain و ligaments ليش؟ ال ligaments هي
+
+141
+00:10:05,990 --> 00:10:10,470
+الأربطة اللي بتربط هدولة العضمتين مع بعض حتى تمنع
+
+142
+00:10:10,470 --> 00:10:14,670
+الزواغان المفصل و كمان nerves و blood vessels ال
+
+143
+00:10:14,670 --> 00:10:20,270
+nerve عشان تعطيني laser orderكمان بيكون ال .. ال
+
+144
+00:10:20,270 --> 00:10:26,170
+bones احنا حكينا innervated أما ال cartilage لأ و
+
+145
+00:10:26,170 --> 00:10:28,590
+ال blood vessels قلنا ال cartilage is not
+
+146
+00:10:28,590 --> 00:10:29,890
+vascularized
+
+147
+00:10:33,590 --> 00:10:39,210
+نروح لل Anatomy of the synovial joint ال Accessory
+
+148
+00:10:39,210 --> 00:10:42,930
+Structure فيها إن حاجة اسمها ال PORSAE ال PORSAE
+
+149
+00:10:42,930 --> 00:10:49,010
+هي عبارة عن sack جابة فيها synovial fluid هذه
+
+150
+00:10:49,010 --> 00:10:52,530
+بتكون موجودة في الأماكن الاحتكاك عشان تمنع
+
+151
+00:10:52,530 --> 00:10:55,090
+الاحتكاك أثناء الحركة يبقى هي
+
+152
+00:11:03,670 --> 00:11:07,150
+أما في كمان نوع تاني من المخدات خلينا نسميهم مخدات
+
+153
+00:11:07,150 --> 00:11:10,870
+احنا اللي هي الـ fat pads دايما distributed along
+
+154
+00:11:10,870 --> 00:11:14,170
+the peripheral of the synovial joint في جوانب ال
+
+155
+00:11:14,170 --> 00:11:19,280
+peripheral joint act as backing materialand it
+
+156
+00:11:19,280 --> 00:11:23,320
+provides some protection بتساعد على حماية هذا
+
+157
+00:11:23,320 --> 00:11:30,520
+المفصل دايما بتملأ الفراغات بين العظام عشان تساعد
+
+158
+00:11:30,520 --> 00:11:34,720
+على ال stability و بتحسن من ال congrance of the
+
+159
+00:11:34,720 --> 00:11:39,280
+joint ايش ال congrance اللي هو تطابق ال joints
+
+160
+00:11:39,280 --> 00:11:44,960
+نفسه؟أما الـ tail bones فهي نهايات ال muscles اللي
+
+161
+00:11:44,960 --> 00:11:47,940
+بتعمل attachment with the bone دائما بال
+
+162
+00:11:47,940 --> 00:11:54,180
+stabilization of the joint وهذا خلينا نقول شكل ال
+
+163
+00:11:54,180 --> 00:11:58,680
+knee joint هو تقريبا ال most complicated joint in
+
+164
+00:11:58,680 --> 00:12:05,050
+the bodyلأنه في كتير من ال .. خليني نقول الأجزاء
+
+165
+00:12:05,050 --> 00:12:10,370
+زي ال articular surfaces زي ال patella، في عندنا
+
+166
+00:12:10,370 --> 00:12:16,250
+ال .. ال intervertebral menisci، في عندنا ال
+
+167
+00:12:16,250 --> 00:12:18,490
+ligaments، في عندنا الكرشيات، ال ligaments، اللي
+
+168
+00:12:18,490 --> 00:12:23,550
+هنشرحهمواحد واحد فهي البورصة هي هذه عشان تعملي
+
+169
+00:12:23,550 --> 00:12:27,650
+passages لتندو زي البنت تندو باتيلا بيكون في عندنا
+
+170
+00:12:27,650 --> 00:12:34,970
+البورصة هي أساس انها تساعد في الحركة هذا هنشرحه
+
+171
+00:12:34,970 --> 00:12:40,240
+عندما نوصل للمفصل البنانيوهذا شكل تاني للـ Tendon
+
+172
+00:12:40,240 --> 00:12:43,820
+Sheets اللي موجودة في ال wrist هذي ال sheets
+
+173
+00:12:43,820 --> 00:12:49,320
+بتساعد على إنه تخلي ال tendons هذه الأوتار هذه في
+
+174
+00:12:49,320 --> 00:12:52,400
+أماكنها لو كان افترضنا إنه فيه مشكلة في واحد من
+
+175
+00:12:52,400 --> 00:12:56,620
+هال sheets هذه هذا ممكن يؤدي لإنه ال tendon
+
+176
+00:12:56,620 --> 00:13:00,460
+مايكونش stable ويعلق يعني مثلما ال trigger fingers
+
+177
+00:13:00,460 --> 00:13:03,340
+أحيانا بيكون له الشخص بيقدر يطني أصابعه لكن
+
+178
+00:13:03,340 --> 00:13:06,240
+مابيقدر يفردها فهذه بيكون فيه مشكلة في ال tendon
+
+179
+00:13:06,240 --> 00:13:07,040
+sheets
+
+180
+00:13:11,740 --> 00:13:15,140
+أما الـ type of joint فاحنا بدنا نعرف أنه في عندنا
+
+181
+00:13:15,140 --> 00:13:20,220
+joints مختلفة ال .. ال access اتكلم عن ال access
+
+182
+00:13:20,220 --> 00:13:24,540
+إذا بنتذكر في أول محاضرة قيلنا أو عرفنا في عندنا
+
+183
+00:13:24,540 --> 00:13:29,140
+ال .. ال plans of movement ال frontal و ال .. و ال
+
+184
+00:13:29,140 --> 00:13:35,000
+sagittal و ال transfers و كل واحد من هدول ال .. ال
+
+185
+00:13:35,000 --> 00:13:39,020
+plans له access فال movement بتصير within the plan
+
+186
+00:13:39,020 --> 00:13:43,510
+around an axisفيه ان بعض ال joints بس ال movement
+
+187
+00:13:43,510 --> 00:13:48,390
+around uniaxial يعني one axis او biaxial او two
+
+188
+00:13:48,390 --> 00:13:52,930
+plans او multiaxial او three plans يعني فلينا احنا
+
+189
+00:13:52,930 --> 00:13:57,710
+نمثل هذا انا بس بدي اوقف لو احنا تكلمنا مثل عن ال
+
+190
+00:13:57,710 --> 00:14:02,410
+shoulder joints هو three axial joints يعني ان انا
+
+191
+00:14:02,410 --> 00:14:05,990
+بقدر اعمل ال movement flexureextension,
+
+192
+00:14:06,270 --> 00:14:11,770
+hyperextension, abduction, adduction, lateral
+
+193
+00:14:11,770 --> 00:14:16,410
+rotation, medial rotation وكمان في حركة هي ال
+
+194
+00:14:16,410 --> 00:14:18,730
+circumduction ايش ال circumduction يعني ان انا
+
+195
+00:14:18,730 --> 00:14:22,720
+بقدر اعمل هذه الحركة في three different axisطيب
+
+196
+00:14:22,720 --> 00:14:27,140
+هذا ليش انا بقدر اشتغل بال shoulder بهذا الشكل او
+
+197
+00:14:27,140 --> 00:14:30,580
+بقدر اعمل هذا ال movement لأن هو semivial joints
+
+198
+00:14:30,580 --> 00:14:34,000
+هو if really movable joints و ال articular
+
+199
+00:14:34,000 --> 00:14:39,740
+surfaces بتسمحلي بهذا النوع من الحركة يعني ان يكون
+
+200
+00:14:39,740 --> 00:14:41,140
+في عندي حركة بال
+
+201
+00:14:56,970 --> 00:15:03,270
+الشكل المفصل هو اللي بيسمح هذا النوع من الحركة
+
+202
+00:15:16,660 --> 00:15:22,060
+deviation median هنا احنا بنسميه Palmer deviation
+
+203
+00:15:22,060 --> 00:15:26,460
+وعلى ال letter n بنسميه radial deviation يبقى في
+
+204
+00:15:26,460 --> 00:15:29,400
+ال anatomical position انا بقدر اعمل flexion
+
+205
+00:15:29,400 --> 00:15:30,580
+extension
+
+206
+00:15:37,960 --> 00:15:42,440
+النتا كاربو فلانجيال جوانز انا بعمل flexion,
+
+207
+00:15:43,120 --> 00:15:49,180
+extension, abduction, adductionأما نروح على الـ
+
+208
+00:15:49,180 --> 00:15:53,260
+Uniaxial زي ال .. ال .. ال elbow joints و ال knee
+
+209
+00:15:53,260 --> 00:15:57,880
+joint as well أنا بقدر أعمل بس flexion extension
+
+210
+00:15:57,880 --> 00:16:01,060
+ال movement هنا عندي بس في الـ Sagittal plane
+
+211
+00:16:01,060 --> 00:16:04,920
+around the frontal axis Sagittal plane around the
+
+212
+00:16:04,920 --> 00:16:08,860
+frontal axis وهذه من ناحية سمية نوع الجد الهنج جد
+
+213
+00:16:08,860 --> 00:16:14,210
+وهلأ هنتعرف على أنواع الجديعني كان هذا أهم إشي في
+
+214
+00:16:14,210 --> 00:16:19,970
+موضوعنا لليوم أما ال types of joints فعنا ال
+
+215
+00:16:19,970 --> 00:16:23,890
+planner ال gliding joint اللي هي ال movement بتكون
+
+216
+00:16:23,890 --> 00:16:29,230
+بس حركة movement بسيطة gliding ال hinge زي ما
+
+217
+00:16:29,230 --> 00:16:34,710
+حكينا وورينا قبل شوية زي ال elbowأما الـ pivot فهي
+
+218
+00:16:34,710 --> 00:16:38,050
+حركة الدوران في حركة ال rotation اللي احنا قبل
+
+219
+00:16:38,050 --> 00:16:42,630
+شوية حكيناها بس بتكون خاصة بس بمفصل نوع ال joint
+
+220
+00:16:42,630 --> 00:16:48,090
+pivot اللي هي حركة دوران ال neck to the right and
+
+221
+00:16:48,090 --> 00:16:53,290
+to the left أما ال combo load joint والصدل joint
+
+222
+00:16:53,290 --> 00:16:58,710
+هنتعرف عليهم one by oneوأكبر المفاصل عندنا بتكون
+
+223
+00:16:58,710 --> 00:17:03,690
+عبارة عن ball and socket في عندنا كرة وموجودة في
+
+224
+00:17:03,690 --> 00:17:08,890
+جيب تحتضنها في هدى بتاعة movement في every plant
+
+225
+00:17:08,890 --> 00:17:14,290
+like the shoulder and the hipنبدأ بالـ Bowel and
+
+226
+00:17:14,290 --> 00:17:19,350
+Socket اللي هو من المفاصلة الـ freely movable
+
+227
+00:17:19,350 --> 00:17:24,910
+joints وفيها movement in the three plans زي ال
+
+228
+00:17:24,910 --> 00:17:32,010
+shoulder and hip joint طيب نشوف أن على الشكل هنا
+
+229
+00:17:32,010 --> 00:17:36,290
+ال hip مهم في عين الأسيطابيولام وفي عين ال head of
+
+230
+00:17:36,290 --> 00:17:49,150
+femurعاملين زي كأنها كرة جوات يعني حاوية وفي
+
+231
+00:17:49,150 --> 00:17:54,210
+عندنا النقطة
+
+232
+00:17:54,210 --> 00:17:58,360
+تانيةزي ما احنا شايفين الـ Condyloid Joint بهذا
+
+233
+00:17:58,360 --> 00:18:01,540
+الشكل الـ Condyloid برضه بيعطينا movement بس in
+
+234
+00:18:01,540 --> 00:18:05,080
+two plan او by axial plan زي الـ
+
+235
+00:18:05,080 --> 00:18:07,960
+Metacarpophalangeal Joints اللي وضحناها قبل شوية
+
+236
+00:18:07,960 --> 00:18:13,500
+ال Condyloid بين ال Metacarpophalangeal Joints اما
+
+237
+00:18:13,500 --> 00:18:20,330
+ال gliding joint فهي عبارةmovement of gliding
+
+238
+00:18:20,330 --> 00:18:25,890
+between the tarsal and carpal bone إذا بتذكروا في
+
+239
+00:18:25,890 --> 00:18:29,910
+الانترن يقولنا في عنا two rows of carpal bone ال
+
+240
+00:18:29,910 --> 00:18:33,030
+proximal row والدستر روه ال movement ما بينهم
+
+241
+00:18:33,030 --> 00:18:37,690
+بتكون فقط gliding بس إزاحة عملية إزاحة أما ال
+
+242
+00:18:37,690 --> 00:18:44,750
+hinge joint فهي عبارة عن ال elbow and knee وكمان
+
+243
+00:18:44,750 --> 00:18:48,450
+between the phalanges أو ال interphalangeal joints
+
+244
+00:18:50,030 --> 00:18:53,350
+طبعا الشيء اللي بيحدد الحركة قلنا شكل المفصل
+
+245
+00:18:53,350 --> 00:18:56,610
+تخيلنا شكل المفصل حسب الصورة بنلاقي أن شكل المفصل
+
+246
+00:18:56,610 --> 00:19:01,550
+ما بيسمح إلا بحركة بهذا الاتجاه أما ال pivot فهو
+
+247
+00:19:01,550 --> 00:19:06,290
+عبارة عن حركة دوران حوالي المحور الحركة هذه إذا ما
+
+248
+00:19:06,290 --> 00:19:09,670
+اتذكر لما اتكلمنا عن ال Atlas و ال Axis اللي هما
+
+249
+00:19:09,670 --> 00:19:14,090
+ال first and second cervical vertebra فقولناالـ
+
+250
+00:19:14,090 --> 00:19:18,470
+Axis فيه إلها الـ Odontoid process فيه هي process
+
+251
+00:19:18,470 --> 00:19:23,910
+موجود في الفتحة أو في الفرمن في ال Axis لأن هما
+
+252
+00:19:23,910 --> 00:19:28,290
+كانت إشكالهم كانت مختلفة إذا بتذكروا وإنها بتسمح
+
+253
+00:19:28,290 --> 00:19:35,980
+بحركة ال rotation هذه بتشكل pivot jointأما السد
+
+254
+00:19:35,980 --> 00:19:41,040
+الجنف هو عامل زي حدوث الفرس أو زي سرج الحصان تمام؟
+
+255
+00:19:41,040 --> 00:19:48,400
+هذا بيسمحي بحركة برضه بيه أكتر من axis احنا بلاحظ
+
+256
+00:19:48,400 --> 00:19:51,840
+ان ال thumb flexion extension abduction abduction
+
+257
+00:19:51,840 --> 00:19:55,320
+وحاجة بنسميها opposition opposition يعني حركة
+
+258
+00:19:55,320 --> 00:19:58,460
+ديران اللي احنا حلقة التصبيح هذه يا جماعة إذا
+
+259
+00:19:58,460 --> 00:20:02,970
+انتوا يعني بتسبحواحركة السفيح هي عبارة عن
+
+260
+00:20:02,970 --> 00:20:08,670
+opposition of the metacarpophalangeal joint of the
+
+261
+00:20:08,670 --> 00:20:09,470
+thumb
+
+262
+00:20:15,620 --> 00:20:20,480
+هنا إذا إحنا شايفين في ال slide هذه الحركة ال
+
+263
+00:20:20,480 --> 00:20:25,020
+planner joins between the navicular and the second
+
+264
+00:20:25,020 --> 00:20:29,840
+and third uniform of the tarsal of the نجواب حد
+
+265
+00:20:29,840 --> 00:20:33,940
+الرسم أنه فيه مفاصل لكن الحركة فيهم بسيطة تصير
+
+266
+00:20:33,940 --> 00:20:37,040
+أثناء ال weight bearing و المشي
+
+267
+00:20:39,400 --> 00:20:43,580
+هيتكلمنا عن الـ Stability فإحنا بن .. يعني الرسم
+
+268
+00:20:43,580 --> 00:20:46,800
+التوضيحي اللي موجود وإحنا بنعرف قاعدة أساسية في
+
+269
+00:20:46,800 --> 00:20:49,040
+الـ Biomechanics إذا في حدا مننا درس الـ
+
+270
+00:20:49,040 --> 00:20:54,040
+Biomechanics إنه كل ما كان الجسم mobile أكتر كل ما
+
+271
+00:20:54,040 --> 00:20:58,540
+قلت بس الـ Stability بعنى إنه في تناسب عكسي بين ال
+
+272
+00:20:58,540 --> 00:21:04,380
+mobility و ال stability كل ما كان الجسم
+
+273
+00:21:05,590 --> 00:21:09,730
+أقل حركة أو حركته أقل فالكل ناكلة stability تبعته
+
+274
+00:21:09,730 --> 00:21:13,810
+أعلى فلتدرجنا بالمفاصل بنلاقي المفاصل في جسم
+
+275
+00:21:13,810 --> 00:21:18,130
+الإنسان بتبدأ من الأقل هم stability وأكثرهم
+
+276
+00:21:18,130 --> 00:21:22,470
+mobility هو shoulder joint لإن بنعمل 180 flexion
+
+277
+00:21:22,470 --> 00:21:28,550
+و180 abduction وبناخد حركة ال rotation بتوصل ل 90
+
+278
+00:21:30,140 --> 00:21:35,320
+فهو لسه stable و كمان شكل المفصل هو بيقلل يعني بي
+
+279
+00:21:35,320 --> 00:21:38,320
+.. يعني شكل المفصل نفسه أنه مافيش فيه congruency
+
+280
+00:21:38,320 --> 00:21:41,940
+كتير مافيش فيه تطابق كتير و بيحتاج لبادل كتير في
+
+281
+00:21:41,940 --> 00:21:47,280
+حاجة اسمهاLabrum حوالين الـGlenoid كبتي في الكبلة
+
+282
+00:21:47,280 --> 00:21:51,100
+بتساعد على ال congruence فهو أقل stable كمان ال
+
+283
+00:21:51,100 --> 00:21:55,260
+hip هو يعني ال stability اللي بيستمدها من كمية ال
+
+284
+00:21:55,260 --> 00:21:59,600
+ligaments اللي موجودة عليه لكن هو كمان less stable
+
+285
+00:21:59,600 --> 00:22:06,320
+جون القلبه بيتدرج هو بيروح ناحية ال stabilityأكتر
+
+286
+00:22:06,320 --> 00:22:10,700
+وقلنا ال amphetrosis joints زي ال intervertebral
+
+287
+00:22:10,700 --> 00:22:13,920
+اللي يسمى stable كمان أكتر هما الأكتر المستابلية
+
+288
+00:22:13,920 --> 00:22:16,380
+اللي هو الأقل هو movement اللي مافيش فيه movement
+
+289
+00:22:16,380 --> 00:22:20,260
+زي السوتشارب of the skull طب هل ايه ده ال type of
+
+290
+00:22:20,260 --> 00:22:25,670
+movement؟ ال type of movement هناانا شرحتها قبل
+
+291
+00:22:25,670 --> 00:22:28,390
+شويه وانا واقفة اقول ان في عندنا abduction و
+
+292
+00:22:28,390 --> 00:22:32,110
+abduction في عندنا dorsiflexion و plantar flexion
+
+293
+00:22:32,110 --> 00:22:37,270
+لما بنتكلم عن الفوت بنتكلم عن dorsal flexion اللي
+
+294
+00:22:37,270 --> 00:22:40,530
+هي flexion and extension plantar اللي انا بروح
+
+295
+00:22:40,530 --> 00:22:45,830
+برجل ناحية ال plantar surface of the foot وفي
+
+296
+00:22:45,830 --> 00:22:51,980
+عندنا flexion و extension و hyper extensionكمان في
+
+297
+00:22:51,980 --> 00:22:55,400
+عندنا ال rotation and circumduction وهو ده وضحنا
+
+298
+00:22:55,400 --> 00:23:01,820
+احنا لما كنا بنتكلم عن انواع المفاصل ال uniaxial و
+
+299
+00:23:01,820 --> 00:23:04,340
+ال multiaxial او ال biaxial
+
+300
+00:23:07,170 --> 00:23:09,950
+في عندنا حركة ال rotation و في عندنا ال
+
+301
+00:23:09,950 --> 00:23:13,590
+circumduction و في كمان حركة فيها supination و
+
+302
+00:23:13,590 --> 00:23:19,070
+antipronation هادية متمثلة بال radio ulnar joints
+
+303
+00:23:19,070 --> 00:23:24,670
+في عندنا حركات في الجهة هي عبارة عنالـ Eversion و
+
+304
+00:23:24,670 --> 00:23:25,650
+الـ Inversion هذه
+
+305
+00:23:25,650 --> 00:23:46,670
+بالفوتﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻﻻ�
+
+306
+00:23:47,240 --> 00:23:50,320
+الـ head of the humerus and gluteal cavity اللي
+
+307
+00:23:50,320 --> 00:23:53,620
+موجودة في الـ scab اللي هو عبارة عن ball and
+
+308
+00:23:53,620 --> 00:23:58,300
+socket فيه كراء وفيه جيل هو loose joint capsule
+
+309
+00:23:58,300 --> 00:24:02,620
+عشان هيك في عنا هو mostly free joint أو freely
+
+310
+00:24:02,620 --> 00:24:06,640
+movable joint وفي عنا money per se عشان بتعمل
+
+311
+00:24:06,640 --> 00:24:13,260
+مخدات أو بتمنع الاحتكاك ما بين العضلات
+
+312
+00:24:13,260 --> 00:24:17,930
+اللي هي بتقوم بالحركة في هذا المكانوطبعا الـ
+
+313
+00:24:17,930 --> 00:24:22,250
+ligament طبيعي وظيفته انه يقلل من ال risk of
+
+314
+00:24:22,250 --> 00:24:25,770
+displacement ويمسك ال two ends of bones هدول في
+
+315
+00:24:25,770 --> 00:24:31,870
+المكان و هو طبعا very movable joint اما ال
+
+316
+00:24:31,870 --> 00:24:39,590
+shoulder command joint طبعا في عندنا حاجة ..
+
+317
+00:24:43,630 --> 00:24:49,590
+الـ shoulder joints هو عبارة محاط بالعديد من الـ
+
+318
+00:24:49,590 --> 00:24:54,070
+ligaments حتى تساعد على حماية هذا المفصل من
+
+319
+00:24:54,070 --> 00:24:57,590
+الزواغات وهو تقريبا من أكتر مفاصلة ممكن يكون معرض
+
+320
+00:24:57,590 --> 00:25:04,230
+لـ dislocation نتيجة حوادث الطرقممكن شد يعني ممكن
+
+321
+00:25:04,230 --> 00:25:06,950
+طفل صغير بس مجرد بنمسكه من أيدي و هيك نروح يحناخل
+
+322
+00:25:06,950 --> 00:25:09,650
+عينه و كتفه يحتاج إلى reduction و بنشوف أن
+
+323
+00:25:09,650 --> 00:25:13,790
+اللاعبين اللي مصارعه اتعرضوا كتير ل shoulder
+
+324
+00:25:13,790 --> 00:25:18,970
+dislocation لأن هو لسه stable joints و هو طبعا
+
+325
+00:25:18,970 --> 00:25:24,570
+محاطب عدد من ال ligament و ال bursite و غيرهأما ال
+
+326
+00:25:24,570 --> 00:25:32,970
+البوجوان فهو هلجو بتكون المفصل من الهيمرس الهيمرس
+
+327
+00:25:32,970 --> 00:25:37,930
+ال lower end of الهيمرس فيها لتروكليا و ال upper
+
+328
+00:25:37,930 --> 00:25:42,780
+end of الهيمرس فيها اسمها لتروكيلار نتشطبعا فيها
+
+329
+00:25:42,780 --> 00:25:45,780
+ان اخر مجموعات موجودة Gladial joint موجود بين
+
+330
+00:25:45,780 --> 00:25:50,080
+الـcapitulum المكان المخصص للـhead of radius على
+
+331
+00:25:50,080 --> 00:25:55,980
+الهيوميراس طبعا بيسمحني بالحركة في one axis في
+
+332
+00:25:55,980 --> 00:26:01,580
+سجنة لبنان around and خلّيني نقول frontal axis هي
+
+333
+00:26:01,580 --> 00:26:06,380
+reflection and extension و ملي reinforcing ملي
+
+334
+00:26:06,380 --> 00:26:09,920
+reinforcing لبنان وهو stable joints ليش stable
+
+335
+00:26:09,920 --> 00:26:14,150
+لأنه less movableهو مش استيابة لأن الحركة فيه
+
+336
+00:26:14,150 --> 00:26:17,830
+قليلة ومحاط بالعديد من ال الكميس وال articular
+
+337
+00:26:17,830 --> 00:26:25,460
+surfaces تبعته فيها congruenceطبعا هذا شكل الـ
+
+338
+00:26:25,460 --> 00:26:30,220
+elbow joints هو في عندنا هي الهيومراس وهي ال head
+
+339
+00:26:30,220 --> 00:26:34,180
+of radius وهي محاط في ال annular ligament عشان
+
+340
+00:26:34,180 --> 00:26:36,400
+يبقى ال head of larsen كتير من الأطفال لما نجيب
+
+341
+00:26:36,400 --> 00:26:38,720
+ونشدهم ونمسكهم من أيدهم بتلاقى بتطلع ال head of
+
+342
+00:26:38,720 --> 00:26:43,060
+radius من ال annular ligament وهذا بيعملهم ألم
+
+343
+00:26:43,060 --> 00:26:47,020
+بحتاج أنه نعملهم حركة خفيفة عشان نرجع المفصل وطبعا
+
+344
+00:26:47,020 --> 00:26:50,040
+على جانبي المفصل في عندنا radial collateral
+
+345
+00:26:50,040 --> 00:26:55,510
+ligamentوال .. و ال .. ال herculateral هي ما تلا
+
+346
+00:26:55,510 --> 00:26:58,730
+حماية هذا المفصل
+
+347
+00:27:00,880 --> 00:27:04,580
+أما الـ hip joints طبعا هذا من ال joints الكبيرة و
+
+348
+00:27:04,580 --> 00:27:07,860
+اللي بتتحمل wet bearing طبعا كتير و هو ball and
+
+349
+00:27:07,860 --> 00:27:12,480
+socket بتكون من ال head of humerus و الacetabulum
+
+350
+00:27:12,480 --> 00:27:17,000
+of coccyx اللي موجودة من ال .. ال pelvic bone هو
+
+351
+00:27:17,000 --> 00:27:21,320
+heavy joint capsule لأن هو بتحمل wet bearing كل
+
+352
+00:27:21,320 --> 00:27:25,540
+وزن الجسم بيكون محمل على ال two hips فعشان هيك
+
+353
+00:27:25,540 --> 00:27:30,600
+بتحتاج إلى الكثير من الحمايةطبعا ال reinforcement
+
+354
+00:27:30,600 --> 00:27:35,400
+بتجيل من ال ligament و طبعا ال freedom أقطت مش شدر
+
+355
+00:27:35,400 --> 00:27:38,940
+لكن هي movement in three blood يعني بيعمل flexion,
+
+356
+00:27:39,040 --> 00:27:42,100
+extension, hyperextension, abduction, adduction,
+
+357
+00:27:42,300 --> 00:27:43,820
+middle rotation, lateral rotation and
+
+358
+00:27:43,820 --> 00:27:44,720
+circumduction
+
+359
+00:27:46,880 --> 00:27:50,100
+حكينا ان هو بول انسكت فبقى طيلة movement in the
+
+360
+00:27:50,100 --> 00:27:53,080
+three plan طبعا في عنا عديد من ال ligaments احنا
+
+361
+00:27:53,080 --> 00:27:56,780
+عارفين ان ال head bones عبارة عن ال alien و ال
+
+362
+00:27:56,780 --> 00:28:00,500
+pupae و ال ischium ده ما احنا شايفين هنا فلازم انه
+
+363
+00:28:00,500 --> 00:28:06,030
+بيكون في عنا ligament بيربط الالفيمر مع هدال
+
+364
+00:28:06,030 --> 00:28:09,750
+العضلات وشوفين تفقه احنا هنا متشابكة ولجانب ان في
+
+365
+00:28:09,750 --> 00:28:13,970
+مكان كان موجود داخل من ال head نفسه الى ال
+
+366
+00:28:13,970 --> 00:28:18,190
+acetabulum هذا عامل زى كأنه زى مصمار كده بس هو رجع
+
+367
+00:28:18,190 --> 00:28:24,860
+منه طبعاموجود بيربط الـ head مع الـ acetabulum و
+
+368
+00:28:24,860 --> 00:28:30,980
+حوالينه في الاليوفميرال لجامنت و في الاسكيوفميرال
+
+369
+00:28:30,980 --> 00:28:35,340
+لجامنت و في البيوكوفميرال لجامنت و هدول لجامنت
+
+370
+00:28:35,340 --> 00:28:41,480
+قوية جدا في ال من هي dense tissue طبعا dense
+
+371
+00:28:41,480 --> 00:28:45,780
+fibrous tissue عشان انها تساعد في ال stabilityأما
+
+372
+00:28:45,780 --> 00:28:48,640
+ال V-zone تقولنا هو most complex zones و ال
+
+373
+00:28:48,640 --> 00:28:53,480
+largest zones of the body طبعا بيحمل وزن كمان أكتر
+
+374
+00:28:53,480 --> 00:28:56,520
+من الوزن اللي بيحمله ال head لإن هو بياخد وزن
+
+375
+00:28:56,520 --> 00:29:01,440
+الجسم كله الابدنى كله في عنا medial and lateral
+
+376
+00:29:01,440 --> 00:29:05,940
+condyle of the testes في مرض تلتحم ال medial و
+
+377
+00:29:05,940 --> 00:29:10,480
+lateral condyles of theproximal end of the tibia
+
+378
+00:29:10,480 --> 00:29:14,360
+,femur articulates anteriorly with العضمة السابونة
+
+379
+00:29:14,360 --> 00:29:18,420
+اللي نسميها البتلة اللي هي أساسها my bone,modified
+
+380
+00:29:18,420 --> 00:29:21,700
+hinge joint طبعا ليش modified لأنه بيسمح
+
+381
+00:29:21,700 --> 00:29:24,930
+بreflection extensionوالقليل من الـ rotation فيه
+
+382
+00:29:24,930 --> 00:29:28,310
+reflection position طبعا strengthened by manual
+
+383
+00:29:28,310 --> 00:29:32,810
+ligaments أنتمبال والمنسكاي اللي هي المنسكاي عبارة
+
+384
+00:29:32,810 --> 00:29:35,910
+عن المخدات الموجودة في المفصل عشان تساعد ال
+
+385
+00:29:35,910 --> 00:29:39,650
+congruence في المفصل وتساعد على ال stability و
+
+386
+00:29:39,650 --> 00:29:43,290
+manual corsage زي ما احنا شايفين عشان تسهل عملية
+
+387
+00:29:43,290 --> 00:29:48,270
+الحركة وهي ال movement طبعته بتكون في ال Sagittal
+
+388
+00:29:48,270 --> 00:29:53,110
+Planeطبعا ال complexity تزايا من عدد من ال
+
+389
+00:29:53,110 --> 00:29:56,750
+ligament اللي موجودة، في عندنا حاجة اسمها إكراشية
+
+390
+00:29:56,750 --> 00:29:59,350
+في ال ligament، في عندنا two meniscus medial and
+
+391
+00:29:59,350 --> 00:30:01,830
+lateral، في عندنا ال lateral collateral ligament،
+
+392
+00:30:01,830 --> 00:30:05,700
+في عندنا ال medial collateral ligamentوان
+
+393
+00:30:05,700 --> 00:30:09,500
+الفيبيولار طبعا الفيبيولار على ناحية الفيبيولا
+
+394
+00:30:09,500 --> 00:30:13,400
+بلاترالي والميديا ال collateral ligament هو على
+
+395
+00:30:13,400 --> 00:30:16,880
+التيبيا بسمي تيبيا ال collateral ligament هذه كلها
+
+396
+00:30:16,880 --> 00:30:22,280
+ال .. ال .. ال ligaments هتساعد على ال stability
+
+397
+00:30:22,280 --> 00:30:27,820
+of the knee joint وتسمح طبعا بالحركةالتغييرات اللي
+
+398
+00:30:27,820 --> 00:30:31,580
+بتصير joint stiffness دائما هي early sign of
+
+399
+00:30:31,580 --> 00:30:34,520
+ageing، بتبقى أنه ال flexibility تبعت الجوانت
+
+400
+00:30:34,520 --> 00:30:37,600
+تتقل، ال fibrous zones طبعا أول حاجة بتصير
+
+401
+00:30:37,600 --> 00:30:42,980
+strengthening لأنها بتقل المرونة تبعتها طبعا في ال
+
+402
+00:30:42,980 --> 00:30:46,630
+sympathiesالـ joint و الـ vertebral column كلها
+
+403
+00:30:46,630 --> 00:30:49,470
+بتصير diminished flexibility و decreased لأنه احنا
+
+404
+00:30:49,470 --> 00:30:53,710
+بنلاحظ أنه الشخص بيقسر كل مزاد في العمر طبعا عملية
+
+405
+00:30:53,710 --> 00:30:57,310
+الطول بتكون أثناء النمو بيثبت الطول بعدين في ال
+
+406
+00:30:57,310 --> 00:31:00,630
+aging بيقسر لأن الفراغ اللي مابين ال vertebral
+
+407
+00:31:00,630 --> 00:31:04,590
+column الفراغ اللي موجود بين المفاصل هذا بقل طبعا
+
+408
+00:31:04,590 --> 00:31:09,950
+بتقل spasticity تبع ال synovial joints و طبعا ليه؟
+
+409
+00:31:09,950 --> 00:31:16,520
+لأن ال blood supply بتقلالعمل والتجارب تساعد على
+
+410
+00:31:16,520 --> 00:31:24,060
+تحسين تبعة الجنس لفترة طويلة، أما الـcycle of life
+
+411
+00:31:24,060 --> 00:31:28,840
+للـarticulation في الـboneكمان بيصير ossification
+
+412
+00:31:28,840 --> 00:31:33,820
+between birth and skeletal maturity الفونتانيلز
+
+413
+00:31:33,820 --> 00:31:38,080
+اللى حكينا عنها في ال cranium بتروح بتصير VLTN
+
+414
+00:31:38,080 --> 00:31:41,820
+بيصير social zone زى ما احنا قدرنا و حكينا و ال
+
+415
+00:31:41,820 --> 00:31:44,760
+effusary plate خلاص بيصير ossified و بيصير no more
+
+416
+00:31:44,760 --> 00:31:51,260
+خليني نقول length لبنها بتعود تطول لعنضها سم معين
+
+417
+00:31:51,260 --> 00:31:55,680
+بيوقف نمو هذه العضام وما بيقول الشخص اللى بيطول
+
+418
+00:31:55,680 --> 00:32:00,020
+اكترمن هاك طبعا كل ما بيكبر ال range of motion
+
+419
+00:32:00,020 --> 00:32:04,880
+بتقل و ال gap بيصير فيه تغيرات ففي عامة كتير من ال
+
+420
+00:32:04,880 --> 00:32:10,900
+skeletal disease ممكن تأدي .. ممكن تكون من ال ..
+
+421
+00:32:10,900 --> 00:32:16,660
+تعمل abnormal growthوبتأثر على المفاصل وفي عندنا
+
+422
+00:32:16,660 --> 00:32:20,020
+بعض ال disease اللي بتكون specific with
+
+423
+00:32:20,020 --> 00:32:23,780
+development period من المشاكل اللي ممكن تصيب
+
+424
+00:32:23,780 --> 00:32:26,980
+العظام اللي هي ال sprain و ال bursitis و التذنعيس
+
+425
+00:32:26,980 --> 00:32:30,260
+ال sprains احنا ممكن ما زمنا في يوم من الأيام
+
+426
+00:32:30,260 --> 00:32:34,440
+تعرضنا للأكل sprain يعني بيصير في لوية الرجل هذه
+
+427
+00:32:34,440 --> 00:32:37,140
+damaged to the cartilage أو ligament أو tendon
+
+428
+00:32:37,140 --> 00:32:42,580
+associated withوطبعا هي عبارة عن حركة من ناحية
+
+429
+00:32:42,580 --> 00:32:47,060
+biomechanics فهي حركة إتلوائية بتصير في المفصل أما
+
+430
+00:32:47,060 --> 00:32:49,340
+ال borsitis احنا كنا نتعرف على ال borsa اللي
+
+431
+00:32:49,340 --> 00:32:53,020
+موجودة عشان نتسهل حركة المفاصل فيمكن يصير فيها
+
+432
+00:32:53,020 --> 00:32:58,020
+inflammation و عادة ما بتصير هذه إلا من ال overuse
+
+433
+00:32:58,020 --> 00:33:02,460
+للجوانب ال tendonitis هي عبارة عن inflammation في
+
+434
+00:33:02,460 --> 00:33:08,500
+ال tendon ممكن تصير نتيجة ال exercise المتكرر
+
+435
+00:33:10,200 --> 00:33:13,660
+الarthritis من المشاكل اللي ممكن نتعرض إليها مع ال
+
+436
+00:33:13,660 --> 00:33:18,480
+aging أو إذا صار فيه ضربة مباشرة على المفصل هي
+
+437
+00:33:18,480 --> 00:33:21,600
+inflammatory or degenerative disease of the joints
+
+438
+00:33:21,600 --> 00:33:26,920
+بتظهر الألم و ال stiffness و ال swelling في ال
+
+439
+00:33:26,920 --> 00:33:33,590
+joints أما اليعني هذه طبعا ال .. ال .. من الأشياء
+
+440
+00:33:33,590 --> 00:33:36,610
+اللي ممكن أنها تحصل زي الـ Gouty Arthritis الناس
+
+441
+00:33:36,610 --> 00:33:40,050
+اللي بيقولك هنده نقرص بينتج عن الأكل اللحوم ال ..
+
+442
+00:33:40,050 --> 00:33:45,630
+ال .. الكتيرة و ال osteoarthritis اللي بتصير أنه
+
+443
+00:33:45,630 --> 00:33:50,050
+التهيبات في ال cartilage و تأكل في ال cartilage
+
+444
+00:33:51,440 --> 00:33:53,900
+بيأدى لـDegrees لـRange of Motion أما
+
+445
+00:33:53,900 --> 00:33:55,660
+الـRheumatoid Arthritis فهذا System Disease
+
+446
+00:33:55,660 --> 00:33:58,600
+Inflammatory Inflammation of the joint result in
+
+447
+00:33:58,600 --> 00:34:02,140
+an autoimmune disease فهو هذا System Disease بيأثر
+
+448
+00:34:02,140 --> 00:34:08,340
+على المفاصل وهذه تقريبا الصورة لبعد المفاصل اللى
+
+449
+00:34:08,340 --> 00:34:11,950
+ممكن تكونيعني الفرق بين ال normal joints و بين ال
+
+450
+00:34:11,950 --> 00:34:16,190
+osteoarthritic joints فاحنا في نهاية محاضرتنا
+
+451
+00:34:16,190 --> 00:34:19,710
+لليوم احنا اتكلمنا فيها عن ال articulations او ال
+
+452
+00:34:19,710 --> 00:34:22,750
+joints of the .. of the body و قلنا اتعرفنا على
+
+453
+00:34:22,750 --> 00:34:27,830
+أهميتها و كمان على أنواعها و عرفنا الفرق بين ال ..
+
+454
+00:34:27,830 --> 00:34:31,930
+ال uniaxial و ال biaxial و ال multiaxial joints و
+
+455
+00:34:31,930 --> 00:34:36,150
+عرفنا انهأهم شيء أنه ال .. ال .. ال .. ال ..
+
+456
+00:34:36,150 --> 00:34:40,530
+التناسب العكسي ما بين ال mobility and stability of
+
+457
+00:34:40,530 --> 00:34:43,710
+the joints و ان شاء الله في المحاضرة القادمة هيكون
+
+458
+00:34:43,710 --> 00:34:46,390
+موضوعنا عن ال nervous system لكم ان شاء الله في
+
+459
+00:34:46,390 --> 00:34:47,250
+المحاضرة القادمة
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E.srt
new file mode 100644
index 0000000000000000000000000000000000000000..fa9d350578f90e8899b01aa0fe1464f339892fe5
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E.srt
@@ -0,0 +1,1015 @@
+1
+00:00:04,990 --> 00:00:09,290
+بسم الله الرحمن الرحيم محاضرتنا اليوم الأخيرة في
+
+2
+00:00:09,290 --> 00:00:14,590
+مساق anatomy هنتكلم فيها عن الجزء الآخر من ال
+
+3
+00:00:14,590 --> 00:00:18,010
+nervous system وهو ال spinal cord. المحاضرة السابقة
+
+4
+00:00:18,010 --> 00:00:22,630
+كانت تتكلم عن ال brain، وقلنا امتداد لل brain في
+
+5
+00:00:22,630 --> 00:00:26,740
+ال central nervous system هو ال spinal cord وهو
+
+6
+00:00:26,740 --> 00:00:30,640
+وظيفته أنه يعمل link between the body regions and
+
+7
+00:00:30,640 --> 00:00:36,040
+the brain. طبعا هو ممكن يكون فيه بعض ال
+
+8
+00:00:36,040 --> 00:00:39,540
+functional independency عن ال brain، زي موضوع ال
+
+9
+00:00:39,540 --> 00:00:44,000
+reflexes. ال spinal cord و ال spinal nerves serve
+
+10
+00:00:44,000 --> 00:00:49,240
+two functions. أول حاجة ال pathway for sensory and
+
+11
+00:00:49,240 --> 00:00:54,470
+motor impulses، وكمان responsible for the reflexes. طب
+
+12
+00:00:54,470 --> 00:00:57,830
+كيف ال pathway من ال sensory؟ لأن احنا لما نبقى
+
+13
+00:00:57,830 --> 00:01:02,270
+ماشيين، واحنا ماشيين نعترض بحجر أو يغزنا دبوس، كيف
+
+14
+00:01:02,270 --> 00:01:05,770
+بنعرف إنه احنا هذا الدبوس غزنا، وبنشرد رجلنا. هذا
+
+15
+00:01:05,770 --> 00:01:08,890
+ال reflex، لكن بيصير interpretation لل impulse هذه
+
+16
+00:01:08,890 --> 00:01:13,760
+as a sensory impulse، بتروح من foot عبر ال spinal
+
+17
+00:01:13,760 --> 00:01:18,660
+cord إلى الدماغ، والإشارة بتيجي كمان من الدماغ لأن
+
+18
+00:01:18,660 --> 00:01:23,460
+إحنا حاسين تحتنا حجر، بنرفع رجلنا، أو عين حفرة،
+
+19
+00:01:23,460 --> 00:01:27,460
+بنتدرك الأمر لأنه بيطلع الأمر على ال brain، بعمل
+
+20
+00:01:27,460 --> 00:01:31,680
+interpretation وببعت ال order المناسب لعضلاتنا عشان
+
+21
+00:01:31,680 --> 00:01:35,280
+تتحرك في الاتجاه المناسب.
+
+22
+00:01:37,280 --> 00:01:42,520
+كمان الـ spinal cord فيه
+
+23
+00:01:42,520 --> 00:01:47,200
+له تقريبا… احنا حكينا عن حجم ال brain، اليوم بنتكلم
+
+24
+00:01:47,200 --> 00:01:51,180
+عن طول ال spinal cord، لأنه عبارة عن قناة طويلة
+
+25
+00:01:51,180 --> 00:01:58,460
+بتبدأ من أسفل الرقبة وبتنتهي في الظهر. طبعا هذه
+
+26
+00:01:58,460 --> 00:02:01,040
+بتاخد تقريبا 42 إلى 45
+
+27
+00:02:01,040 --> 00:02:06,100
+centimeter على حسب الطول، وهي عبارة عن cylinder،
+
+28
+00:02:06,100 --> 00:02:12,900
+عبارة عن قنية cylindrical shape، طبعا إلها بعض ال
+
+29
+00:02:12,900 --> 00:02:17,620
+flattened anterior and posterior. في إلها ال
+
+30
+00:02:17,620 --> 00:02:20,200
+depressions.
+
+31
+00:02:20,800 --> 00:02:24,520
+في ال dorsal، وفي عندنا ال ventral، أو هو الدورسال ال
+
+32
+00:02:24,520 --> 00:02:27,580
+posterior، و ال ventral هو ال anterior median
+
+33
+00:02:27,580 --> 00:02:28,440
+fissure.
+
+34
+00:02:32,300 --> 00:02:37,920
+هي شكل ال cross-sectional view،
+
+35
+00:02:37,920 --> 00:02:43,800
+ال sectional view بيعطينا زي ما احنا شايفين شكل ال spinal cord
+
+36
+00:02:43,800 --> 00:02:47,320
+في ال anterior horn، في عندنا ال posterior horn،
+
+37
+00:02:47,320 --> 00:02:50,500
+في عندنا ال median fissure اللي اتكلمنا عنه قبل
+
+38
+00:02:50,500 --> 00:02:56,960
+شوية، في عندنا ال posterior sulcus بهذا
+
+39
+00:02:56,960 --> 00:03:03,140
+الشكل. طبعا في عندنا ال dorsal spinal nerve root، و
+
+40
+00:03:03,140 --> 00:03:08,760
+في عندنا ال dorsal ganglia. هنشوفهم واحد واحد في
+
+41
+00:03:08,760 --> 00:03:14,080
+ال structure. ال spinal cord فيه عندنا كذا region، في
+
+42
+00:03:14,080 --> 00:03:17,880
+عندنا cervical، وفي عندنا lumbar، وفي عندنا sacral،
+
+43
+00:03:18,240 --> 00:03:22,020
+والcoccygeal. طبعا ال cervical هي عبارة عن ال
+
+44
+00:03:22,020 --> 00:03:26,200
+continuation للمدولا oblongata، وفيها eight spinal
+
+45
+00:03:26,200 --> 00:03:32,280
+nerves. أما thoracic فهي عبارة عن twelve pairs of
+
+46
+00:03:32,280 --> 00:03:37,200
+spinal، أو thoracic spinal nerves. وفي عندنا five
+
+47
+00:03:37,200 --> 00:03:41,680
+lumbar spinal nerves، وفي عندنا five sacral spinal
+
+48
+00:03:41,680 --> 00:03:46,800
+nerves، وفي عندنا only one coccygeal spinal nerve.
+
+49
+00:03:46,800 --> 00:03:51,540
+ودول مجموعهم بيكون 31 pairs of spinal
+
+50
+00:03:51,540 --> 00:03:55,420
+nerves، زي ما احنا شايفينهم بالرسم التوضيحي هذا.
+
+51
+00:03:55,420 --> 00:03:58,760
+عندنا ثمانية cervical، عندنا twelve thoracic، عندنا
+
+52
+00:03:58,760 --> 00:04:02,620
+five lumbar، وعندنا five sacral، و only one
+
+53
+00:04:02,620 --> 00:04:09,130
+coccygeal، زي ما احنا شايفين في الصورة. طبعا ال
+
+54
+00:04:09,130 --> 00:04:13,990
+spinal cord فيه ثلاثة أجزاء. هو shorter than the
+
+55
+00:04:13,990 --> 00:04:17,050
+vertebral canal. ال vertebral canal اللي قلنا
+
+56
+00:04:17,050 --> 00:04:22,670
+بتنتهي في نهاية ال coccyx، لكن ال spinal cord ب ينتهي
+
+57
+00:04:22,670 --> 00:04:27,490
+على ال L1. طبعا في عندنا ال conus medullaris، هي
+
+58
+00:04:27,490 --> 00:04:33,280
+ال tapered  end،  خلينا نقول بتبدأ تتبوز فيها ال
+
+59
+00:04:33,280 --> 00:04:36,880
+inferior end of the spinal cord، و mark of the
+
+60
+00:04:36,880 --> 00:04:40,980
+official end of the spinal cord proper. بنتهي عندها
+
+61
+00:04:40,980 --> 00:04:45,000
+ال spinal cord، وفي عندها بعدها بتيجي الكودا equina،
+
+62
+00:04:45,000 --> 00:04:49,460
+هي عبارة عن مجموعة nerve roots، group of axon،
+
+63
+00:04:49,460 --> 00:04:53,680
+projecting inferiorly from the spinal cord. هي تحت
+
+64
+00:04:53,680 --> 00:04:58,680
+ال conus medullaris. وفي عندنا في النهاية ال filum
+
+65
+00:04:58,680 --> 00:05:00,860
+terminale.
+
+66
+00:05:13,400 --> 00:05:17,140
+والخلل في الكودا إيكوينا يعتبر lower motor neuron
+
+67
+00:05:17,140 --> 00:05:22,000
+lesion. أما أي خلل في ال spinal، أو Damage لل Spinal
+
+68
+00:05:22,000 --> 00:05:26,220
+cord فوق ال cauda equina، فهي upper motor neuron
+
+69
+00:05:26,220 --> 00:05:32,080
+lesion. وهذا كتير مهم في تحديد نوع ال motor neuron
+
+70
+00:05:32,080 --> 00:05:35,680
+lesion اللي معانا. طبعا في عندنا Spinal
+
+71
+00:05:35,680 --> 00:05:41,150
+meninges، هم اللي اتكلمنا عنهم، احنا السيد… اتكلمنا عن
+
+72
+00:05:41,150 --> 00:05:44,830
+في ال brain، في عندنا three meninges: في ال dura mater،
+
+73
+00:05:44,830 --> 00:05:49,750
+وفي ال arachnoid، وفي ال pia mater. وفي هدول
+
+74
+00:05:49,750 --> 00:05:53,410
+نفسه اللي هم continuation على ال spinal cord، هي
+
+75
+00:05:53,410 --> 00:05:59,550
+عبارة عن continuous of cranial meninges. طبعا ال
+
+76
+00:05:59,550 --> 00:06:04,250
+structures that encircle the spinal cord،
+
+77
+00:06:04,250 --> 00:06:08,110
+نأخذها من ال superficial للعميق، في ال… في ال
+
+78
+00:06:08,110 --> 00:06:11,130
+superficial،  أول طبقة ال superficial هي ال bones of
+
+79
+00:06:11,130 --> 00:06:15,690
+vertebrae. وبعدين في عندنا ال epidural space، و
+
+80
+00:06:15,690 --> 00:06:20,370
+بعدين الدورا ماتر، اللي بنسميها الأم الجافية، و
+
+81
+00:06:20,370 --> 00:06:24,190
+بعدين ال subdural space، وفي عندنا ال arachnoid، وفي
+
+82
+00:06:24,190 --> 00:06:28,130
+عندنا ال subarachnoid space، وفي نهاية
+
+83
+00:06:28,130 --> 00:06:32,590
+ال pia mater، اللي هي الأم الحنون اللي بتكون ملاسقة
+
+84
+00:06:32,590 --> 00:06:39,290
+لل spinal cord، وهي زي ما احنا شايفينها بالرسم،
+
+85
+00:06:39,290 --> 00:06:43,450
+الرسم موضح فيه عندنا ال spinal cord في المنتصف،
+
+86
+00:06:43,450 --> 00:06:49,770
+وبيبدأ من البيامتر. هي أول layer، هي هنا ال spinal
+
+87
+00:06:49,770 --> 00:06:54,290
+cord، بعدين البيامتر، بعدين ال subarachnoid، و
+
+88
+00:06:54,290 --> 00:07:00,810
+بعدين ال arachnoid، بعدين بنروح للdura، ونقلب
+
+89
+00:07:00,810 --> 00:07:04,630
+dura، ال epidural space اللي هو فوق الدورا، و بنتهي هنا
+
+90
+00:07:04,630 --> 00:07:10,550
+بالعظمة اللي هي ال vertebrae نفسها. وهنا بتبدأ
+
+91
+00:07:10,550 --> 00:07:14,050
+ال spinal nerves
+
+92
+00:07:14,050 --> 00:07:19,430
+تظهر. وزي ما احنا شايفين، اللي بتطلع ال spinal
+
+93
+00:07:19,430 --> 00:07:23,370
+nerves من ال intervertebral foramen. وزي ما احنا
+
+94
+00:07:23,370 --> 00:07:27,030
+شايفين هنا في عندنا ال anterior part of the
+
+95
+00:07:27,030 --> 00:07:30,210
+vertebra، اللي هو ال body، و ال posterior part اللي
+
+96
+00:07:30,210 --> 00:07:34,710
+هو ال spinous processes، و ال transverse processes of the vertebrae.
+
+97
+00:07:37,330 --> 00:07:42,150
+وهذا الشكل برضه بيوضح بالظبط  ال dura mater.
+
+98
+00:07:42,150 --> 00:07:47,050
+وفي عندنا ال arachnoid،
+
+99
+00:07:47,050 --> 00:07:51,390
+وفي عندنا هذا ال delicate sheet، اللي هو اللي بين
+
+100
+00:07:51,390 --> 00:07:55,540
+البيامتر. و زي ما احنا شايفين في عندنا عدد من ال blood
+
+101
+00:07:55,540 --> 00:08:01,680
+vessels، و blood arteries، أو veins عشان تغذي ال spinal
+
+102
+00:08:01,680 --> 00:08:07,200
+cord. وهنا شايفين ال posterior و ال anterior spinal nerve
+
+103
+00:08:07,200 --> 00:08:11,360
+كيف بياخد ال anterior root و ال posterior root و
+
+104
+00:08:11,360 --> 00:08:16,820
+بيلتحموا مع بعض، وبيكونوا ال spinal nerve. طبعا ال
+
+105
+00:08:16,820 --> 00:08:20,740
+spinal nerves عبارة عن 31 pairs of spinal nerves،
+
+106
+00:08:20,740 --> 00:08:27,160
+بتوصل ال central nervous system إلى receptors، و
+
+107
+00:08:27,160 --> 00:08:31,400
+إلى ال muscles و glands. Each spinal nerve بيكون mixed،
+
+108
+00:08:31,400 --> 00:08:34,600
+لأن في عندنا motor، في عندنا sensory. ال motor
+
+109
+00:08:34,600 --> 00:08:40,460
+بيجيب ال order من ال brain لل spinal cord، ولأجزاء
+
+110
+00:08:40,460 --> 00:08:45,910
+ال body. والعكس، ال sensory بياخد من أجزاء ال body
+
+111
+00:08:45,910 --> 00:08:49,230
+إلى ال spinal cord، ثم إلى ال brain for
+
+112
+00:08:49,230 --> 00:08:52,570
+interpretation. ال sensory axons originate from
+
+113
+00:08:52,570 --> 00:08:57,690
+receptors، و ال motor axons originate from the
+
+114
+00:08:57,690 --> 00:09:02,150
+spinal cord. في أن ال anterior and posterior roots
+
+115
+00:09:02,460 --> 00:09:06,320
+**(This section appears to be a repeated error, likely a transcription mistake.  It's removed)**
+
+122
+00:09:20,020 --> 00:09:25,340
+rami of spinal nerve. في
+
+123
+00:09:25,340 --> 00:09:28,100
+عندنا ال posterior، أو dorsal ramus، اللي هو
+
+124
+00:09:28,100 --> 00:09:31,460
+innervates ال muscles و skin of the back. وفي عندنا
+
+125
+00:09:31,460 --> 00:09:34,600
+ال ventral ramus، أو ال anterior ramus، هي ال
+
+126
+00:09:34,600 --> 00:09:37,320
+largest branch، وبيكون ال plexus اللي عندنا،
+
+127
+00:09:37,320 --> 00:09:41,240
+هنتكلم عنهم، و innervates ال anterior and lateral
+
+128
+00:09:41,240 --> 00:09:43,960
+trunk of the upper and lower limbs. يبقى ال
+
+129
+00:09:43,960 --> 00:09:47,140
+posterior، اللي علاقة بـ skin and muscles of the
+
+130
+00:09:47,140 --> 00:09:52,040
+back. أما ال anterior، لل upper and lower limbs. وهذا
+
+131
+00:09:52,040 --> 00:09:57,030
+الكلام مهم جدا، احنا نحفظه و نفهمه. في ال dorsal
+
+132
+00:09:57,030 --> 00:10:00,030
+root اللي هي posterior، أو sensory root. وفي ال
+
+133
+00:10:00,030 --> 00:10:03,910
+ventral root، اللي هي ال anterior root. يبقى ال
+
+134
+00:10:03,910 --> 00:10:09,870
+anterior هي عبارة عن motor axons، أما ال
+
+135
+00:10:09,870 --> 00:10:15,970
+posterior فهي sensory axons. ال posterior axons of
+
+136
+00:10:15,970 --> 00:10:19,170
+sensory neurons are in the dorsal root. أما ال ventral
+
+137
+00:10:19,170 --> 00:10:23,260
+فهي axons of motor neurons. Cell bodies are in the
+
+138
+00:10:23,260 --> 00:10:26,400
+spinal cord. في أن ال dorsal root كلها cell
+
+139
+00:10:26,400 --> 00:10:29,900
+bodies of sensory neurons whose axons conduct
+
+140
+00:10:29,900 --> 00:10:33,280
+impulses inward from the periphery of the body.
+
+141
+00:10:33,280 --> 00:10:36,840
+بتاخد من ال periphery of the body. وفي أن ال
+
+142
+00:10:36,840 --> 00:10:42,980
+spinal nerve هي عبارة عن اتحاد ال ventral و ال
+
+143
+00:10:42,980 --> 00:10:47,360
+dorsal roots عشان يطلع أنها ال spinal nerve. وقلنا
+
+144
+00:10:47,360 --> 00:10:50,460
+كل spinal nerve فيها sensory and motor
+
+145
+00:10:54,180 --> 00:10:58,320
+هذا الرسم التوضيحي بيوضح لنا كيف بيصير ال dorsal
+
+146
+00:10:58,320 --> 00:11:04,380
+root ganglia. وفي عندنا هنا ال ventral branch اللي
+
+147
+00:11:04,380 --> 00:11:07,220
+من ال spinal cord، أو ال ventral ramus. وزي ما نشوفين
+
+148
+00:11:07,220 --> 00:11:12,520
+احنا، ال dorsal، أو ال posterior ramus، واتحادهم
+
+149
+00:11:12,520 --> 00:11:18,600
+اللي هو بيطلع عندنا ال spinal nerve، ال spinal nerve
+
+150
+00:11:18,600 --> 00:11:20,980
+ال spinal nerve.
+
+151
+00:11:23,710 --> 00:11:28,730
+طب نروح لحاجة اسمها ال dermatomes. ال dermatomes هي
+
+152
+00:11:28,730 --> 00:11:34,550
+عبارة عن specific segment of the skin supplied by a
+
+153
+00:11:34,550 --> 00:11:39,770
+single spinal nerve. All spinal nerves innervate a
+
+154
+00:11:39,770 --> 00:11:42,710
+segment of the skin and associated muscles of the
+
+155
+00:11:42,710 --> 00:11:48,080
+dermatome. Except C1. C1 ما… ما… مالوش dermatome.
+
+156
+00:11:48,080 --> 00:11:51,740
+ال dermatomes map هي عبارة عن sensory segment of skin
+
+157
+00:11:51,740 --> 00:11:55,320
+of the body associated with the spinal nerve. وهذه
+
+158
+00:11:55,320 --> 00:11:59,260
+ال map اللي احنا بنحب دائما نصورها، ونحطها في
+
+159
+00:11:59,260 --> 00:12:05,010
+مراكزنا، وقصورنا، حتى ما ننسى،  لأنها بتحدد لنا
+
+160
+00:12:05,010 --> 00:12:10,350
+زي ما شايفين، الإحساس في كل مكان، وكل منطقة من الجسم
+
+161
+00:12:10,350 --> 00:12:13,390
+زي ما احنا شايفين، منطقة ال thumb هنا في ال
+
+162
+00:12:13,390 --> 00:12:17,670
+anterior part، C6.
+
+163
+00:12:17,670 --> 00:12:22,050
+مثلا، وفي ال posterior part of the thumb برضه C6،
+
+164
+00:12:22,050 --> 00:12:27,510
+C7 مثلا في ال posterior part، في ال index و ال
+
+165
+00:12:27,510 --> 00:12:31,010
+middle finger.
+
+166
+00:12:32,160 --> 00:12:39,020
+وشايفين كمان هنا ال C8 مثلا هي في ال fourth و ال
+
+167
+00:12:39,020 --> 00:12:44,180
+fifth finger. وزي ما احنا شايفين هنا، كل جزء من
+
+168
+00:12:44,180 --> 00:12:50,290
+الجسم على الجلد، فيه منطقة معينة من ال spinal
+
+169
+00:12:50,290 --> 00:12:53,750
+nerve. زي ما شايفين مثلا S1 هنا، على ال lateral part
+
+170
+00:12:53,750 --> 00:12:58,490
+of the… of the foot، مع ال little toe. وهنا
+
+171
+00:12:58,490 --> 00:13:06,910
+برضه شايفين بالخلف S1، و S2 وهكذا. فهذا كله بيوضح ال
+
+172
+00:13:06,910 --> 00:13:11,890
+mapping بتاعة ال sensory، أو dermatomes of the
+
+173
+00:13:11,890 --> 00:13:16,650
+sensory nerves. هنا في حاجة اسمها intercostal nerves،
+
+174
+00:13:16,650 --> 00:13:21,410
+هي عبارة عن anterior rami of spinal nerves من T1 إلى
+
+175
+00:13:21,410 --> 00:13:27,770
+T11. بتترتب في ال spaces، تعمل عاملة زي sandwich، between
+
+176
+00:13:27,770 --> 00:13:32,750
+two adjacent vertebrae. هدول اللي احنا شايفينهم
+
+177
+00:13:32,750 --> 00:13:35,510
+بالرسم. Spinal nerves.
+
+178
+00:13:40,700 --> 00:13:45,560
+طبعا في حاجة اسمها nerve plexuses. في عندنا أربعة
+
+179
+00:13:45,560 --> 00:13:49,460
+major plexuses، أو principle nerve plexuses،
+
+180
+00:13:49,460 --> 00:13:56,340
+هي a network of interweaving anterior rami of
+
+181
+00:13:56,340 --> 00:14:00,640
+the spinal nerves. ال nerve plexuses بتقول لنا إن
+
+182
+00:14:00,640 --> 00:14:04,520
+احنا ال anterior rami هي المسؤولة عن ال upper and
+
+183
+00:14:04,520 --> 00:14:08,380
+lower limbs. و هدول ال plexuses بتغذي ال upper and
+
+184
+00:14:08,380 --> 00:14:12,210
+lower limbs.  النرف بلكساس على جميع الجانب الأيمن والأيسر
+
+185
+00:14:12,210 --> 00:14:16,930
+من الجسم. النرف بلكساس مختلطة، إلى عدد من
+
+186
+00:14:16,930 --> 00:14:20,610
+الأعصاب. يعني عدد من الأعصاب التي تدخل في plexus، و
+
+187
+00:14:20,610 --> 00:14:24,610
+تغذي الجسم. سنأخذ منهم ال principle ones اللي هو
+
+188
+00:14:24,610 --> 00:14:28,910
+ال cervical plexus، و ال brachial plexus، هدول للأعلى ال limbs.
+
+189
+00:14:28,910 --> 00:14:32,130
+وفي ال lumbar plexus،
+
+223
+00:16:59,380 --> 00:17:03,830
+الـCentral Nervous System و الـSpinal Cord
+
+224
+00:17:03,830 --> 00:17:07,390
+في عندنا الـmotor inference اللي هي اللي خلتني
+
+225
+00:17:07,390 --> 00:17:12,830
+أقول المواصلات الهابطة، وفي عندنا الـmuscle
+
+226
+00:17:12,830 --> 00:17:17,350
+organs اللي هي بدها تعمل، خليني أقول، الحركة
+
+227
+00:17:17,350 --> 00:17:22,620
+تبعدني عن هذا الخطر، يعني المستقبلات على الجلد
+
+228
+00:17:22,620 --> 00:17:27,100
+تستقبل...بتشعر بالخطر، بتبعتها عن طريق الـ
+
+229
+00:17:27,100 --> 00:17:29,880
+afferent neurons إلى الـcentral nervous system،
+
+230
+00:17:29,880 --> 00:17:33,580
+بتنزل عن طريق الـefferent motor neurons على الـ
+
+231
+00:17:33,580 --> 00:17:38,100
+muscles أو الـglands حتى تستجيب. في عندنا الـ
+
+232
+00:17:38,100 --> 00:17:42,120
+monosynaptic reflex زي الـknee jerk أو simplest of all
+
+233
+00:17:42,120 --> 00:17:46,140
+reflexes. هنا ما فيش interneurons لأنها مباشرة
+
+234
+00:17:46,140 --> 00:17:52,160
+بتيجي على مركز الـreflex و بترجع للعضلة نفسها زي
+
+235
+00:17:52,160 --> 00:17:59,590
+الـpatellar أو knee jerk reflex، مونوسينابتيِك ريفلكس، أما
+
+236
+00:17:59,590 --> 00:18:03,250
+البوليسينابتيِك ريفلكس have a more complex neural
+
+237
+00:18:03,250 --> 00:18:07,690
+pathway، بده number of synapses، فيه interneurons
+
+238
+00:18:07,690 --> 00:18:14,840
+within the reflex arc، has more components، أكثر تأخير
+
+239
+00:18:14,840 --> 00:18:20,280
+مستمرة بين المحفز والإجابة. طبعا هنا الاختبار في
+
+240
+00:18:20,280 --> 00:18:23,140
+موقع الكلينيكال، يمكن أن يكون استخدام الـreflexes
+
+241
+00:18:23,140 --> 00:18:29,360
+لتشخيص مجموعة من الأمراض،  أو جزء من الفحص العصبي
+
+242
+00:18:29,360 --> 00:18:30,120
+(remove repeated phrases)
+
+243
+00:18:30,120 --> 00:18:31,240
+(remove repeated phrases)
+
+244
+00:18:31,240 --> 00:18:32,400
+(remove repeated phrases)
+
+245
+00:18:32,400 --> 00:18:32,960
+(remove repeated phrases)
+
+246
+00:18:32,960 --> 00:18:34,440
+(remove repeated phrases)
+
+247
+00:18:34,440 --> 00:18:39,040
+منdamage في الـnervous system أو الـmuscle. طبعا احنا أول
+
+248
+00:18:39,040 --> 00:18:41,920
+حاجة بنروح على دكتور الأعصاب يفحص الـreflexes بس
+
+249
+00:18:41,920 --> 00:18:47,580
+لأنها بتبين حالة الـcentral nervous system.  A reflex
+
+250
+00:18:47,580 --> 00:18:51,780
+response may be اما normal، اما hypoactive، أو
+
+251
+00:18:51,780 --> 00:18:55,080
+hyperactive. الـnormal reflex هو الطبيعي، أما
+
+252
+00:18:55,080 --> 00:18:57,720
+hypoactive معناه reflex ضعيف، hyperactive
+
+253
+00:18:57,720 --> 00:19:01,550
+exaggerated reflex، يعني بيدل على  نقص في
+
+254
+00:19:01,550 --> 00:19:09,930
+الوظيفة العصبية، يعني  طريقة مبالغ فيها مثلا في الـ
+
+255
+00:19:09,930 --> 00:19:13,130
+clinical application. في عندنا cerebral injuries
+
+256
+00:19:13,130 --> 00:19:17,470
+and abnormalities. ممكن يكون في عندنا على الـ
+
+257
+00:19:17,470 --> 00:19:20,970
+concussion. عبارة عن concussion  في الـbrain،
+
+258
+00:19:20,970 --> 00:19:25,070
+concussion  يسمى الارتجاج في الـbrain. بيكون الـ
+
+259
+00:19:25,070 --> 00:19:29,270
+brain jarred against the cranium. بيصير فيه وكأنه
+
+260
+00:19:29,270 --> 00:19:34,690
+انخداش كده في الـbrain،  زي في حالة حوادث الطرق اللي
+
+261
+00:19:34,690 --> 00:19:40,120
+اتكلمنا عنها في المحاضرة السابقة. بيكون صار ضربة في
+
+262
+00:19:40,120 --> 00:19:44,680
+الدماغ داخل الكرانيوم، انهزت أو انخدشت كده، بيصير
+
+263
+00:19:44,680 --> 00:19:48,440
+فيها  loss of consciousness، ممكن بيصير
+
+264
+00:19:48,440 --> 00:19:53,080
+temporary loss of memory. بيقل الذاكرة وبيصير
+
+265
+00:19:53,080 --> 00:19:57,960
+أحيانا mental clouding. بيصير الشخص مش كتير مركز و
+
+266
+00:19:57,960 --> 00:20:02,680
+مدرك، وبيصيب صداع شديد، وطبعا بيصير recovery
+
+267
+00:20:02,680 --> 00:20:08,360
+أحيانا complete، أو دائما بيكون usually. أنا بصير
+
+268
+00:20:08,360 --> 00:20:13,960
+بأتكلم على cerebrovascular accidents. فهي من الأمراض اللي بتصيب الـ
+
+269
+00:20:13,960 --> 00:20:18,880
+brain زي الـstroke. بيصير sudden interruption في الـ
+
+270
+00:20:18,880 --> 00:20:22,120
+blood flow. بتوقف الـblood، بيصير block نتيجة blood
+
+271
+00:20:22,120 --> 00:20:27,100
+clot أو انسداد في أحد الشرايين، وطبعا في بعض
+
+272
+00:20:27,100 --> 00:20:33,330
+الـbrain tissue بيصير فيها dying. أما الـcerebral
+
+273
+00:20:33,330 --> 00:20:37,750
+palsy فهي حالة من الـmotor impairment في الـbirth
+
+274
+00:20:37,750 --> 00:20:41,850
+بتكون ناتجة عن الـblocked cerebral blood vessel
+
+275
+00:20:41,850 --> 00:20:46,530
+during development. بتصاحبها seizures اللي هي
+
+276
+00:20:46,530 --> 00:20:51,730
+التشنجات، وبيصاحبها learning disabilities، وخاصة هذه
+
+277
+00:20:51,730 --> 00:20:57,150
+الأعراض بيصيب الأطفال، الـnumber ممكن pre- or
+
+278
+00:20:57,150 --> 00:21:01,330
+pre- or postnatal. وبيؤدي إلى، أو بنقول أي حادث
+
+279
+00:21:01,330 --> 00:21:05,650
+بتعرض له الطفل في الـbrain.  على الـbrain يصير عنده
+
+280
+00:21:05,650 --> 00:21:09,970
+damage قبل سن سنتين، فهو cerebral palsy، زي
+
+281
+00:21:09,970 --> 00:21:13,670
+حالات الـcar accidents، زي حالات الغرق قبل سن
+
+282
+00:21:13,670 --> 00:21:18,030
+سنتين. هذا أيضا بيعطي لأن هذه فترة development of
+
+283
+00:21:18,030 --> 00:21:22,150
+الـbrain، لأن الـbrain ما كانش مكتمل. نقوم بهذه
+
+284
+00:21:22,150 --> 00:21:28,330
+بنكون أنهينا محاضراتنا في مساق الـanatomy، وأنا
+
+285
+00:21:28,330 --> 00:21:31,450
+بتمنى أن يكون وجودي معاكم  في الفترة
+
+286
+00:21:31,450 --> 00:21:38,860
+السابقة، خلينا نقول، يعني وضع بعض اللمسات، أو
+
+287
+00:21:38,860 --> 00:21:42,220
+التركيز على بعض النقاط اللي لازم احنا نحفظها، و
+
+288
+00:21:42,220 --> 00:21:45,920
+لازم احنا نعرفها في مجال الـanatomy. Online، لأن
+
+289
+00:21:45,920 --> 00:21:49,760
+مساق الـanatomy مساق كتير مهم للناس اللي بتدرس
+
+290
+00:21:49,760 --> 00:21:55,390
+الـhealth professions، لأنه بيتعامل
+
+291
+00:21:55,390 --> 00:21:59,130
+مع صحة الإنسان. عشان تتعامل مع صحة الإنسان، هذا لازم
+
+292
+00:21:59,130 --> 00:22:03,670
+يكون لديك معرفة بتشريح أعضاء الإنسان. وبهيك إن شاء الله
+
+293
+00:22:03,670 --> 00:22:07,070
+نلتقي معاكم في مساقات أخرى. ويعطيكم العافية.
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..3ba14f41b2bd2570b297a1284ced322314b4d8e2
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E_postprocess.srt
@@ -0,0 +1,1172 @@
+1
+00:00:04,990 --> 00:00:09,290
+بسم الله الرحمن الرحيم محاضرتنا اليوم الأخيرة في
+
+2
+00:00:09,290 --> 00:00:14,590
+مساقر ال anatomy هنتكلم فيها عن الجزء الأخر من ال
+
+3
+00:00:14,590 --> 00:00:18,010
+nervous system وهو ال spinal cord المحاضرة السابقة
+
+4
+00:00:18,010 --> 00:00:22,630
+كانت بتتكلم عن ال brain وقلنا امتداد لل brain في
+
+5
+00:00:22,630 --> 00:00:26,740
+ال central nervous system هو ال spinal cordوهو
+
+6
+00:00:26,740 --> 00:00:30,640
+وظيفته إنه يعمل link between the body regions and
+
+7
+00:00:30,640 --> 00:00:36,040
+the brain طبعا هو ممكن يكون فيه عنده بعض ال
+
+8
+00:00:36,040 --> 00:00:39,540
+functional independency عن ال brain زي موضوع ال
+
+9
+00:00:39,540 --> 00:00:44,000
+reflexes ال spinal cord و ال spinal nerves serve
+
+10
+00:00:44,000 --> 00:00:49,240
+two functions أول حاجة ال pathway for sensory and
+
+11
+00:00:49,240 --> 00:00:54,470
+motor impulses وكمان responsible of thereflexes طب
+
+12
+00:00:54,470 --> 00:00:57,830
+كيفي ال pathway من ال sensory؟ لأن احنا لما نبقى
+
+13
+00:00:57,830 --> 00:01:02,270
+ماشيين و احنا ماشيين بتعتر بحجر او بيغزنا دبوس كيف
+
+14
+00:01:02,270 --> 00:01:05,770
+بنعرف انه احنا هذا الدبوس غزنا و بنشرد رجلنا هذا
+
+15
+00:01:05,770 --> 00:01:08,890
+ال reflex لكن بيصير interpretation لل impulse هذه
+
+16
+00:01:08,890 --> 00:01:13,760
+as a sensory impulse بتروحمن الفوت عبر الـ spinal
+
+17
+00:01:13,760 --> 00:01:18,660
+cord على الدماغ والإشارة بتيجي كمان من الدماغ لإن
+
+18
+00:01:18,660 --> 00:01:23,460
+إحنا حاسين تحتنا حجر بنرفع رجلنا أو عينا حفرة
+
+19
+00:01:23,460 --> 00:01:27,460
+بنتدرك الأمر لإنه بيطلع الأمر على ال brain بعمل
+
+20
+00:01:27,460 --> 00:01:31,680
+interpretation وبعت ال order المناسب لعضلاتنا عشان
+
+21
+00:01:31,680 --> 00:01:35,280
+تتحرك في الاتجاه المناسب
+
+22
+00:01:37,280 --> 00:01:42,520
+كمان ال .. ال .. ال spinal .. ال spinal cord فيه
+
+23
+00:01:42,520 --> 00:01:47,200
+له تقريبا احنا حكينا عن حجم ال brain اليوم بنتكلم
+
+24
+00:01:47,200 --> 00:01:51,180
+عن طول ال spinal cord لإن هو عبارة عن قناة طويلة
+
+25
+00:01:51,180 --> 00:01:58,460
+بتبدأ من أسفل الرقبة و بتنتهي في الظهرطبعا هذه
+
+26
+00:01:58,460 --> 00:02:01,040
+بتاخد تقريبا اتنين و أربعين لخمسة و أربعين
+
+27
+00:02:01,040 --> 00:02:06,100
+centimeter على حسب الطول و هي عبارة عن cylinder
+
+28
+00:02:06,100 --> 00:02:12,900
+عبارة عن قنا cylindrical شاب طبعا إلها بعض ال
+
+29
+00:02:12,900 --> 00:02:17,620
+flattened anterior and posterior في إلها ال
+
+30
+00:02:17,620 --> 00:02:20,200
+depressions
+
+31
+00:02:20,800 --> 00:02:24,520
+في الدورسل وفي عندنا ال ventral أو هو الدورسل ال
+
+32
+00:02:24,520 --> 00:02:27,580
+posterior و ال ventral هو ال anterior median
+
+33
+00:02:27,580 --> 00:02:28,440
+facial
+
+34
+00:02:32,300 --> 00:02:37,920
+هي شكل ال .. ال cross-sectional .. ال sectional
+
+35
+00:02:37,920 --> 00:02:43,800
+view بيعطينا زي ما احنا شايفين شكل ال spinal cord
+
+36
+00:02:43,800 --> 00:02:47,320
+في ال anterior horn، في عندنا ال posterior horn،
+
+37
+00:02:47,320 --> 00:02:50,500
+في عندنا ال median fissure اللي اتكلمنا عنه قبل
+
+38
+00:02:50,500 --> 00:02:56,960
+شوية، في عندناال sulcus ال posterior sulcusي بهذا
+
+39
+00:02:56,960 --> 00:03:03,140
+الشكل طبعا في عندنا ال dorsal spinal nerve road و
+
+40
+00:03:03,140 --> 00:03:08,760
+في عندنا ال dorsal ganglia هنشوفهم واحد و واحد في
+
+41
+00:03:08,760 --> 00:03:14,080
+ال structure ال spinal cord في عندنا كذا region في
+
+42
+00:03:14,080 --> 00:03:17,880
+عندنا cervical و في عندنا lumbar و في عندنا sacral
+
+43
+00:03:18,240 --> 00:03:22,020
+الكوكسيجيال، طبعا ال cervical هي عبارة عن ال
+
+44
+00:03:22,020 --> 00:03:26,200
+continuation للمدلة longata وفيها eight spinal
+
+45
+00:03:26,200 --> 00:03:32,280
+nerves أما thoracic فهي عبارة عن twelve pairs of
+
+46
+00:03:32,280 --> 00:03:37,200
+spinal أو thoracic spinal nerve وفي عندنا five
+
+47
+00:03:37,200 --> 00:03:41,680
+lumbarSpinal nerve وفى عندنا five sacral spinal
+
+48
+00:03:41,680 --> 00:03:46,800
+nerve وفى عندنا only one coccygeal spinal nerve
+
+49
+00:03:46,800 --> 00:03:51,540
+وهدولة مجموعة بيكون واحد و تلاتين pairs of spinal
+
+50
+00:03:51,540 --> 00:03:55,420
+nerve زى ما احنا شايفينهم بالرسم التوضيحى هذا
+
+51
+00:03:55,420 --> 00:03:58,760
+عندنا تمانية cervical عندنا twelve thoracic عندنا
+
+52
+00:03:58,760 --> 00:04:02,620
+five lumbar وعندنا five sacral و only one
+
+53
+00:04:02,620 --> 00:04:09,130
+coccygealزي ما احنا شايفين في الصورة طبعا ال
+
+54
+00:04:09,130 --> 00:04:13,990
+spinal cord فيله تلت أجزاء هو shorter than the
+
+55
+00:04:13,990 --> 00:04:17,050
+vertebral canal ال vertebral canal اللي قولنا
+
+56
+00:04:17,050 --> 00:04:22,670
+بتنتهي في نهاية الcoccyx لكن ال spinal cord بنتهي
+
+57
+00:04:22,670 --> 00:04:27,490
+على ال tube طبعا في عندنا ال conus medialaris هي
+
+58
+00:04:27,490 --> 00:04:33,280
+ال tabard المدققة خلنا نقول بتبدأ يتبوز فيهاالـ
+
+59
+00:04:33,280 --> 00:04:36,880
+inferior end of the spinal cord وmark of the
+
+60
+00:04:36,880 --> 00:04:40,980
+official end of the spinal cord proper بنتهي عندها
+
+61
+00:04:40,980 --> 00:04:45,000
+ال spinal cord وفي عندها بعدها بتيجي الكودة equina
+
+62
+00:04:45,000 --> 00:04:49,460
+هي عبارة عن مجموعة nerve roots group of axon
+
+63
+00:04:49,460 --> 00:04:53,680
+project inferiorly from the spinal cord هي تحت
+
+64
+00:04:53,680 --> 00:04:58,680
+الkonus medullaris وفي عندنا في نهاية ال filament
+
+65
+00:04:58,680 --> 00:05:00,860
+ال film terminal
+
+66
+00:05:13,400 --> 00:05:17,140
+والخلل في القودا إيكوينا تعتبر lower motor neuron
+
+67
+00:05:17,140 --> 00:05:22,000
+lesion أما أي خلل في الـ spinalأو Damage لـ Spinal
+
+68
+00:05:22,000 --> 00:05:26,220
+Corp فوق ال code Aquina فهي Upper Motor Neuron
+
+69
+00:05:26,220 --> 00:05:32,080
+Lesion وهذا كتير مهم في تحديد نوع ال motor ال
+
+70
+00:05:32,080 --> 00:05:35,680
+neuron lesion اللي معاشورة طبعا في عندنا Spinal
+
+71
+00:05:35,680 --> 00:05:41,150
+meninges هم اللي اتكلمنا عنهم احناالسيد اتكلمنا عن
+
+72
+00:05:41,150 --> 00:05:44,830
+في ال brain في عندنا three meninges في ال durable
+
+73
+00:05:44,830 --> 00:05:49,750
+matter وفي ال arachnoid وفي ال biomatter وفي هدولة
+
+74
+00:05:49,750 --> 00:05:53,410
+نفسهم اللي هم continuation على ال spinal cord هي
+
+75
+00:05:53,410 --> 00:05:59,550
+عبارة عن continuous of cranial meningesطبعا ال
+
+76
+00:05:59,550 --> 00:06:04,250
+structure that in .. that encircle the spinal cord
+
+77
+00:06:04,250 --> 00:06:08,110
+ناخده من ال superficial لديه في ال .. في ال
+
+78
+00:06:08,110 --> 00:06:11,130
+superficial مصدفة ال superficial هي ال bones of
+
+79
+00:06:11,130 --> 00:06:15,690
+vertebra و بعدين في عندنا ال epidural space و
+
+80
+00:06:15,690 --> 00:06:20,370
+بعدين دي الدورة المطر اللي بنسميها الأم الجافية و
+
+81
+00:06:20,370 --> 00:06:24,190
+بعدين ال subdural spaceوفي عندنا ال arachnoid وفي
+
+82
+00:06:24,190 --> 00:06:28,130
+عندنا ال subdural هي subarachnoid space وفي نهاية
+
+83
+00:06:28,130 --> 00:06:32,590
+ال biomatter اللي هي الأم الحنون اللي بتكون ملاسقة
+
+84
+00:06:32,590 --> 00:06:39,290
+لل spinal cord وهي زي ما احنا شايفينهم بالرسم،
+
+85
+00:06:39,290 --> 00:06:43,450
+الرسم ماضي فيها عندنا ال spinal cordفي المنتصف
+
+86
+00:06:43,450 --> 00:06:49,770
+وبيبدأ من البيامتر هي اول level هي هنا ال spinal
+
+87
+00:06:49,770 --> 00:06:54,290
+cord بعدين البيامتر و بعدين ال subarachnoid و
+
+88
+00:06:54,290 --> 00:07:00,810
+بعدين ال arachnoid و بعدين بنروح لديورة و نقلب
+
+89
+00:07:00,810 --> 00:07:04,630
+ديورة ال space اللي هو فوق الديورة و بنتهيأ هنا
+
+90
+00:07:04,630 --> 00:07:10,550
+بالبالعضمة اللي هي ال vertebra نفسها و هنا بتبدأ
+
+91
+00:07:10,550 --> 00:07:14,050
+ال spinal nerve
+
+92
+00:07:14,050 --> 00:07:19,430
+تظهر و في زي ما احنا شايفين اللي بتطلع ال spinal
+
+93
+00:07:19,430 --> 00:07:23,370
+nerve من ال intervertebral foramen و زي ما احنا
+
+94
+00:07:23,370 --> 00:07:27,030
+شايفين هنا في عندنا ال anterior part of the
+
+95
+00:07:27,030 --> 00:07:30,210
+vertebra اللي هو ال body و ال posterior part اللي
+
+96
+00:07:30,210 --> 00:07:34,710
+هو ال spines و ال transverse process of the spine
+
+97
+00:07:37,330 --> 00:07:42,150
+وهذا الشكل برضه بيوضح بالظبط أنها الـ Deuterometer
+
+98
+00:07:42,150 --> 00:07:47,050
+وفي عندنا الاركنويد
+
+99
+00:07:47,050 --> 00:07:51,390
+وفي عندنا هذا الـ Delicate sheet اللي هو اللي بيها
+
+100
+00:07:51,390 --> 00:07:55,540
+متر وزي ما احنا شايفين في عندناعدد من ال blood
+
+101
+00:07:55,540 --> 00:08:01,680
+vessels و كانت arteries او دين عشان تغذي ال spinal
+
+102
+00:08:01,680 --> 00:08:07,200
+cord وهنا شايفين ال posterior و ال spinal nerve
+
+103
+00:08:07,200 --> 00:08:11,360
+كيف بياخد ال anterior root و ال posterior root و
+
+104
+00:08:11,360 --> 00:08:16,820
+بتحدوا مع بعض و بتلعن ال spinal nerveطبعا ال
+
+105
+00:08:16,820 --> 00:08:20,740
+spinal nerve عبارة عن ال 31 pairs of spinal nerve
+
+106
+00:08:20,740 --> 00:08:27,160
+connect ال central nervous system to receptors و
+
+107
+00:08:27,160 --> 00:08:31,400
+ال muscle and gland، each spinal nerve بيكون mixed
+
+108
+00:08:31,400 --> 00:08:34,600
+لإن في عندنا motor، في عندنا sensory، ال motor
+
+109
+00:08:34,600 --> 00:08:40,460
+بيجيب ال order من ال brain لspinal cord و لأجزاء
+
+110
+00:08:40,460 --> 00:08:45,910
+ال bodyوالعكس الـ sensory بياخد من أجزاء ال body
+
+111
+00:08:45,910 --> 00:08:49,230
+إلى ال spinal cord ثم إلى ال brain for
+
+112
+00:08:49,230 --> 00:08:52,570
+interpretation ال sensory axon originated from
+
+113
+00:08:52,570 --> 00:08:57,690
+receptors و ال motor axon originated from the
+
+114
+00:08:57,690 --> 00:09:02,150
+spinal cord في أن ال anterior and posterior root
+
+115
+00:09:02,460 --> 00:09:06,320
+وهذا البرامج تصبح جزء من البرامج التجاربية البرامج
+
+116
+00:09:06,320 --> 00:09:09,380
+التجاربية البرامج التجاربية البرامج التجاربية
+
+117
+00:09:09,380 --> 00:09:11,160
+البرامج التجاربية البرامج التجاربية البرامج
+
+118
+00:09:11,160 --> 00:09:12,900
+التجاربية البرامج التجاربية البرامج التجاربية
+
+119
+00:09:12,900 --> 00:09:16,320
+البرامج التجاربية البرامج التجاربية البرامج
+
+120
+00:09:16,320 --> 00:09:19,060
+التجاربية البرامج التجاربية البرامج التجاربية
+
+121
+00:09:19,060 --> 00:09:20,020
+البرامج التجاربية البرامج التجاربية البرامج
+
+122
+00:09:20,020 --> 00:09:25,340
+التجاربيةرامي of spinal nerve of spinal nerve في
+
+123
+00:09:25,340 --> 00:09:28,100
+عندنا ال posterior or dorsal ramus اللي هو
+
+124
+00:09:28,100 --> 00:09:31,460
+innervate ال muscle and skin of the back وفي عندنا
+
+125
+00:09:31,460 --> 00:09:34,600
+ال ventral ramus او ال anterior ramus هي ال
+
+126
+00:09:34,600 --> 00:09:37,320
+largest branch وبيتكومل ال plexus اللي عندنا
+
+127
+00:09:37,320 --> 00:09:41,240
+هنتكلم عنهمو innervate ال anterior and lateral
+
+128
+00:09:41,240 --> 00:09:43,960
+trunk of the upper and lower limb يبقى ال
+
+129
+00:09:43,960 --> 00:09:47,140
+posterior اللي علاقة بال skin and muscle of the
+
+130
+00:09:47,140 --> 00:09:52,040
+back أما ال anterior لل upper and lower limb و هذا
+
+131
+00:09:52,040 --> 00:09:57,030
+الكلام مهم جدا إحنا نحفظه و نفهمهفينا الـ dorsal
+
+132
+00:09:57,030 --> 00:10:00,030
+root اللي هي posterior or sensorial root وفينا الـ
+
+133
+00:10:00,030 --> 00:10:03,910
+ventral root اللي هي الـ anterior root يبقى ال
+
+134
+00:10:03,910 --> 00:10:09,870
+motor ال anterior هي عبارة عن motor axons أما ال
+
+135
+00:10:09,870 --> 00:10:15,970
+posterior فهي sensory axons ال posterior axon of
+
+136
+00:10:15,970 --> 00:10:19,170
+sensor neuron in the dorsal root أما ال ventral
+
+137
+00:10:19,170 --> 00:10:23,260
+فهي axon of motor neuronscells body are in the
+
+138
+00:10:23,260 --> 00:10:26,400
+spinal cord في أن الـdorsal root كان كلها cell
+
+139
+00:10:26,400 --> 00:10:29,900
+body of sensor neurons whose acts on conduct
+
+140
+00:10:29,900 --> 00:10:33,280
+impulse inward from the peripheral of the body
+
+141
+00:10:33,280 --> 00:10:36,840
+بتاخد من ال peripheral of the body وفي أن ال
+
+142
+00:10:36,840 --> 00:10:42,980
+spinal nerve هي عبارة عن اتحاد ال ventral و ال
+
+143
+00:10:42,980 --> 00:10:47,360
+dorsal roots عشان يطلع أنها ال spinal nerve وقولنا
+
+144
+00:10:47,360 --> 00:10:50,460
+كل spinal nerve فيها sensory and motor
+
+145
+00:10:54,180 --> 00:10:58,320
+هذا الرسم التوضيحي بوضح لنا كيف بيصير الـ dorsal
+
+146
+00:10:58,320 --> 00:11:04,380
+root ganglia وفي عندنا هنا ال ventral branch اللي
+
+147
+00:11:04,380 --> 00:11:07,220
+ال spinal cord او ال ventral رعمي و زي ما نشايفين
+
+148
+00:11:07,220 --> 00:11:12,520
+احنا ال dorsal او ال posterior الرعمي واتحادهم
+
+149
+00:11:12,520 --> 00:11:18,600
+اللي هو بيطلع عندنا ال spinal ال spinal cord ال
+
+150
+00:11:18,600 --> 00:11:20,980
+spinal nerve اسمها ال spinal nerve
+
+151
+00:11:23,710 --> 00:11:28,730
+طب نروح لحاجة اسمها ال dermatones ال dermatones هي
+
+152
+00:11:28,730 --> 00:11:34,550
+عبارة عن specific segment of the skin supplied by
+
+153
+00:11:34,550 --> 00:11:39,770
+single spinal nerve all spinal nerves innervate a
+
+154
+00:11:39,770 --> 00:11:42,710
+segment of the skin and associated with the
+
+155
+00:11:42,710 --> 00:11:48,080
+dermatomeExcept C1، C1 ما .. ما .. مالوش ديرماتون
+
+156
+00:11:48,080 --> 00:11:51,740
+الـ Dermatons map هي عبارة عن sensory segment skin
+
+157
+00:11:51,740 --> 00:11:55,320
+of the body associated with the spinal nerve و هذه
+
+158
+00:11:55,320 --> 00:11:59,260
+ال map اللي احنا بنحب دائما نصورها و نحطها في
+
+159
+00:11:59,260 --> 00:12:05,010
+مراكزنا و أقصرنا حتى ماكن بس بنحفظلأنه هان بتحددنا
+
+160
+00:12:05,010 --> 00:12:10,350
+زي ما شايفين الإحساس في كل مكان وكل منطقة من الجسم
+
+161
+00:12:10,350 --> 00:12:13,390
+زي ما احنا شايفين منطقة ال thumb هنا في ال
+
+162
+00:12:13,390 --> 00:12:17,670
+anterior part C6
+
+163
+00:12:17,670 --> 00:12:22,050
+مثلا و في ال posterior part of the thumb برضه C6،
+
+164
+00:12:22,050 --> 00:12:27,510
+C7 مثلا في ال posterior part في ال index و ال
+
+165
+00:12:27,510 --> 00:12:31,010
+third finger
+
+166
+00:12:32,160 --> 00:12:39,020
+وشايفين كمان هنا ال C8 مثلا هي في ال fourth و ال
+
+167
+00:12:39,020 --> 00:12:44,180
+fifth finger و زي ما احنا شايفين هنا كل جزء من
+
+168
+00:12:44,180 --> 00:12:50,290
+الجسم على الجلد فيه بيغزي منطقةمعينة من الـ spinal
+
+169
+00:12:50,290 --> 00:12:53,750
+nerve زي ما شايفين مثلا S1 هنا ع ال lateral part
+
+170
+00:12:53,750 --> 00:12:58,490
+of the .. of the foot مع ال little finger و هان
+
+171
+00:12:58,490 --> 00:13:06,910
+برضه شايفين بالخلف S1 و S2 و هكذا فهذا كله بيوضحها
+
+172
+00:13:06,910 --> 00:13:11,890
+ال mapping تبعت ال sensory أو dermatomes of the
+
+173
+00:13:11,890 --> 00:13:16,650
+sensory nerveهنا في حاجة اسمها Intercostal nerves
+
+174
+00:13:16,650 --> 00:13:21,410
+هي عبارة عن الانتررومي of spinal nerves من T1 ل
+
+175
+00:13:21,410 --> 00:13:27,770
+T11 تترفل في الاسبس تعمل عاملة زي ساندويش between
+
+176
+00:13:27,770 --> 00:13:32,750
+two adjacent vertebra هدول اللي احنا شايفينهم
+
+177
+00:13:32,750 --> 00:13:35,510
+بالرسم Spinal nerve
+
+178
+00:13:40,700 --> 00:13:45,560
+طبعا في حاجة اسمها if plexus ال .. في عندنا أربعة
+
+179
+00:13:45,560 --> 00:13:49,460
+measure of plexuses أو principle ال nerve plexus
+
+180
+00:13:49,460 --> 00:13:56,340
+هي a network of a inter waving anterior rami of
+
+181
+00:13:56,340 --> 00:14:00,640
+the spinal nerve ال nerve plexuses بتقولنا لإن
+
+182
+00:14:00,640 --> 00:14:04,520
+احنا ال anterior rami هي المسؤولة عن ال upper and
+
+183
+00:14:04,520 --> 00:14:08,380
+lower limb و هدولة ال plexuses بتغضي ال upper and
+
+184
+00:14:08,380 --> 00:14:12,210
+lowerالنيرف بليكساس على جميع الجانب اليسرى و
+
+185
+00:14:12,210 --> 00:14:16,930
+اليسرى من الجسم نيرف بليكساس مختلط إلى عدد من
+
+186
+00:14:16,930 --> 00:14:20,610
+النام نيرف يعني عدد من النار التي تدخل الفيروس و
+
+187
+00:14:20,610 --> 00:14:24,610
+أسلوب الجسم سنأخذ منهم البنصيبلز اللي هو
+
+188
+00:14:24,610 --> 00:14:28,910
+الcervical plexus و الbrachial plexus هدولة للأعلى
+
+189
+00:14:28,910 --> 00:14:32,130
+اللمب و في ال lumbar plexus و ال sacral plexus
+
+190
+00:14:32,130 --> 00:14:37,600
+للأعلى اللمبفي حاجة اسمها Reflexes هذي Fast
+
+191
+00:14:37,600 --> 00:14:42,920
+Stereotype Inborn Protective Actions طبعا يعني هي
+
+192
+00:14:42,920 --> 00:14:49,380
+عبارة عن حركات لا إيرادية سريعة نمطية بتساعد على
+
+193
+00:14:49,380 --> 00:14:52,900
+حماية الجسم هذا اللي بتصير لما احنا بنلمس أي إش
+
+194
+00:14:52,900 --> 00:14:56,800
+ثقون فبنهرب إيدنا بشكنا دبوس فعالسريع احنا بنسحب
+
+195
+00:14:56,800 --> 00:15:03,790
+إيدنا أو رجلنا بنتعرض مثلا لأي مخاطرة أوأو مثلا
+
+196
+00:15:03,790 --> 00:15:10,030
+نار بندعس على نار أو غيره فبتلاقي فورا بت .. بنشرد
+
+197
+00:15:10,030 --> 00:15:14,590
+إيدنا أو رجلنا عن المكان or care at the spinal
+
+198
+00:15:14,590 --> 00:15:18,490
+cord and brain stem level maybe eithermono
+
+199
+00:15:18,490 --> 00:15:22,950
+-synaptic أو poly-synaptic طبعا كله بيحتاج all
+
+200
+00:15:22,950 --> 00:15:26,270
+-equal stimulus at receptors بتصير stimulation
+
+201
+00:15:26,270 --> 00:15:30,130
+للـreceptors الموجودة في المكان على طول بتعمل
+
+202
+00:15:30,130 --> 00:15:34,070
+sensory information relay بتوصل هذه الinformation
+
+203
+00:15:34,070 --> 00:15:38,470
+processing at the level ال central nervous system
+
+204
+00:15:38,470 --> 00:15:41,990
+بتروح ال central nervous system على ال brain على
+
+205
+00:15:41,990 --> 00:15:44,730
+ال spinal cord أو بتطلع على ال brain stem و
+
+206
+00:15:44,730 --> 00:15:47,370
+activation of the motor response عشان أنه احنا
+
+207
+00:15:47,680 --> 00:15:51,880
+انهرب ايدنا او رجلنا من المكان و بيصير في عندنا
+
+208
+00:15:51,880 --> 00:15:56,620
+response ال peripheral effector سواء كانت ال
+
+209
+00:15:56,620 --> 00:16:00,640
+muscles or ال glands طبعا بنحتاج هنا receptors و
+
+210
+00:16:00,640 --> 00:16:02,660
+في عندنا afferent neurons ال receptors هي
+
+211
+00:16:02,660 --> 00:16:07,180
+المستقبلات للألم او لالإحساس هذا الـ Afferent
+
+212
+00:16:07,180 --> 00:16:12,560
+neurons هي اللي بتروح من ال periphery إلى ال
+
+213
+00:16:12,560 --> 00:16:16,380
+central nervous system نحتاج ل integration تفسير
+
+214
+00:16:16,380 --> 00:16:21,940
+لهذا الموضوع الترجمة في ال central nervous system
+
+215
+00:16:21,940 --> 00:16:25,820
+وفي عندنا ال afferent neuronsاللي هي ال .. ال ..
+
+216
+00:16:25,820 --> 00:16:30,460
+ال neurose المسؤولة عن تنزيل ال .. المعلومة أو ال
+
+217
+00:16:30,460 --> 00:16:33,460
+order وفي عندنا ال effectors اللي هي ال muscles or
+
+218
+00:16:33,460 --> 00:16:36,900
+gland اللي بتستجيب لهذه ال ..
+
+219
+00:16:40,300 --> 00:16:45,320
+الراسم التوضيحي للـ Reflexes هي عبارة عن Automatic
+
+220
+00:16:45,320 --> 00:16:50,900
+Subconscious Responses to the stimuli within or
+
+221
+00:16:50,900 --> 00:16:55,740
+outside the body في عندنا Sensory Afferent Neurons
+
+222
+00:16:55,740 --> 00:16:59,380
+هي Sensory Receptors وفي عندنا بتروح على
+
+223
+00:16:59,380 --> 00:17:03,830
+الـCentral Nervous Systems وSpinal Cord أوفالمصر
+
+224
+00:17:03,830 --> 00:17:07,390
+في عندنا ال motor inference اللي هي اللي خليني
+
+225
+00:17:07,390 --> 00:17:12,830
+أقول المواصلات ال .. الهابطة وفي عندنا ال muscle
+
+226
+00:17:12,830 --> 00:17:17,350
+orgland اللي هي بدها تعملي خليني أقول الحركة
+
+227
+00:17:17,350 --> 00:17:22,620
+تبعدني عن هذهالمخاطرة يعني المستقبلات على الجذب
+
+228
+00:17:22,620 --> 00:17:27,100
+تستقبل .. بتشعر بالخطر، بتبعتها عن طريق الـ
+
+229
+00:17:27,100 --> 00:17:29,880
+afferent neurons إلى ال central nervous system،
+
+230
+00:17:29,880 --> 00:17:33,580
+بتنزل عن طريق الafferent motor neuron على ال
+
+231
+00:17:33,580 --> 00:17:38,100
+muscles أو ال glands حتى تستجيبهنا في عندنا الـ
+
+232
+00:17:38,100 --> 00:17:42,120
+monosynaptic زي الـ knee jerk أو simplest of all
+
+233
+00:17:42,120 --> 00:17:46,140
+reflexes هنا مافيش inter neurons لأنها مباشرة
+
+234
+00:17:46,140 --> 00:17:52,160
+بتيجي على مركز ال reflex و بترجع للعضلة نفسها زي
+
+235
+00:17:52,160 --> 00:17:59,590
+البتلر أو knee jerk reflexمونو سيناتيك رفليكس أما
+
+236
+00:17:59,590 --> 00:18:03,250
+ال بولي سيناتيك رفليكس have more complex in neural
+
+237
+00:18:03,250 --> 00:18:07,690
+pathway بده number of synapses فيه inter neurons
+
+238
+00:18:07,690 --> 00:18:14,840
+within the reflex has more componentsأكثر تأخير
+
+239
+00:18:14,840 --> 00:18:20,280
+مستمرة بين المشاركة والإجابة. طبعا هنا الاختبار في
+
+240
+00:18:20,280 --> 00:18:23,140
+موقع الكلينيكال يمكن أن يكون استخدام الـ reflexes
+
+241
+00:18:23,140 --> 00:18:29,360
+لتجارب مجموعة مخصصة ونيرب مخصص مخصص أو جزء من جزء
+
+242
+00:18:29,360 --> 00:18:30,120
+من الجزء من الجزء من الجزء من الجزء من الجزء من
+
+243
+00:18:30,120 --> 00:18:31,240
+الجزء من الجزء من الجزء من الجزء من الجزء من الجزء
+
+244
+00:18:31,240 --> 00:18:32,400
+من الجزء من الجزء من الجزء من الجزء من الجزء من
+
+245
+00:18:32,400 --> 00:18:32,960
+الجزء من الجزء من الجزء من الجزء من الجزء من الجزء
+
+246
+00:18:32,960 --> 00:18:34,440
+الجزء من الجزء من الجزء من الجزء من الجزء من الجزء
+
+247
+00:18:34,440 --> 00:18:39,040
+منdamage في nervous system or muscle طبعا احنا أول
+
+248
+00:18:39,040 --> 00:18:41,920
+حاجة بروح على دكتور الأعصاب تفحص ال reflexش بس
+
+249
+00:18:41,920 --> 00:18:47,580
+انها بتبين حالة ال central nervous system a reflex
+
+250
+00:18:47,580 --> 00:18:51,780
+response may be اما normal اما hypoactive او
+
+251
+00:18:51,780 --> 00:18:55,080
+hyperactive ال normal reflex هو الطبيعي اما
+
+252
+00:18:55,080 --> 00:18:57,720
+hypoactive معناه reflex ضييف hyperactive
+
+253
+00:18:57,720 --> 00:19:01,550
+exaggerated reflexيعني بيدرب على النيفة جروحه هو
+
+254
+00:19:01,550 --> 00:19:09,930
+الرجل خطأ في يعني مرفوع الطريقة عنيفة مثلافي ال
+
+255
+00:19:09,930 --> 00:19:13,130
+clinical application في عندنا cerebral injuries
+
+256
+00:19:13,130 --> 00:19:17,470
+and abnormalities ممكن يكون في عندنا على ال
+
+257
+00:19:17,470 --> 00:19:20,970
+concussion عبارة عن ال concussion ال brain
+
+258
+00:19:20,970 --> 00:19:25,070
+concussion يسمى الارتجاج في ال brain بيكون ال
+
+259
+00:19:25,070 --> 00:19:29,270
+brain jarred against ال cranium بيصير فيه و كأنه
+
+260
+00:19:29,270 --> 00:19:34,690
+انخض كده ال brain جواد زي في حالة حوادث الطرق اللي
+
+261
+00:19:34,690 --> 00:19:40,120
+اتكلمنا عنها في المحاضرة السابقةبيكون صار ضربة في
+
+262
+00:19:40,120 --> 00:19:44,680
+الدماغ داخل الكرانيوم انهزت او انخدت كده بيصير
+
+263
+00:19:44,680 --> 00:19:48,440
+فيها بتاعها loss of consciousness ممكن بيصير
+
+264
+00:19:48,440 --> 00:19:53,080
+temporarily loss of memory بيقل الذاكرة و بيصير
+
+265
+00:19:53,080 --> 00:19:57,960
+احيانا mental cloudings بيصير الشخص مش كتير مركز و
+
+266
+00:19:57,960 --> 00:20:02,680
+مدرك و بيصيب صداع شديد و طبعا بيصير recovery
+
+267
+00:20:02,680 --> 00:20:08,360
+احيانا complete او دائما بيكون usuallyأنا بصير
+
+268
+00:20:08,360 --> 00:20:13,960
+بروفاسكيلار اكسيدنس فهي من الأمراض اللي بتصيب ال
+
+269
+00:20:13,960 --> 00:20:18,880
+brain زي ال stroke بصير sudden interruption في ال
+
+270
+00:20:18,880 --> 00:20:22,120
+blood flow بتوقف ال blood بصير block نتيجة blood
+
+271
+00:20:22,120 --> 00:20:27,100
+block اقلط أو انسداد في أحد الشرايين و طبعا في بعض
+
+272
+00:20:27,100 --> 00:20:33,330
+ال brain ال tissue بصير فيها dyingأما الـ cerebral
+
+273
+00:20:33,330 --> 00:20:37,750
+palsy فهي حالة من الـ motor impairment في ال birth
+
+274
+00:20:37,750 --> 00:20:41,850
+بتكون ناجحة عن الـ blocked cerebral blood vessel
+
+275
+00:20:41,850 --> 00:20:46,530
+during development بتصير معها ال seizures اللي هي
+
+276
+00:20:46,530 --> 00:20:51,730
+التشنجاتوبيتبعها learning disabilities وخاصة هذي
+
+277
+00:20:51,730 --> 00:20:57,150
+بسبب الفرصة بيصيب الأطفال ال number ممكن pre or
+
+278
+00:20:57,150 --> 00:21:01,330
+pre or postnatal وبيقدي إلى او بنقول اي حادث
+
+279
+00:21:01,330 --> 00:21:05,650
+بتعرضله الطفل في ال brainعلى ال brand يصير عنده
+
+280
+00:21:05,650 --> 00:21:09,970
+brand دمج قبل سن سنتين فهو يعاد سيرفرال بلس زي
+
+281
+00:21:09,970 --> 00:21:13,670
+حالات ال car accidents زي الحالات الغرق قبل سن
+
+282
+00:21:13,670 --> 00:21:18,030
+سنتين هذا أيضا بيعاد لأن هذه فترة development of
+
+283
+00:21:18,030 --> 00:21:22,150
+ال brand لأن ال brand ماكنش مكتملنقوم بهذه احنا
+
+284
+00:21:22,150 --> 00:21:28,330
+بنكون أنهينا محاضراتنا لفي مساق ال anatomy وانا
+
+285
+00:21:28,330 --> 00:21:31,450
+بتمنى ان يكونوا وجودي معاكم ساعتكم في الفترة
+
+286
+00:21:31,450 --> 00:21:38,860
+السابقة في خلينا نقوليعني وضع بعض اللمسات أو
+
+287
+00:21:38,860 --> 00:21:42,220
+التركيز على بعض النقاط اللي لازم احنا نحفظها و
+
+288
+00:21:42,220 --> 00:21:45,920
+لازم احنا نعرفها في مجال ال Anatomy Online لأن
+
+289
+00:21:45,920 --> 00:21:49,760
+لمساق ال Anatomy ممثقة كتير مهمة للناس اللي بتدرس
+
+290
+00:21:49,760 --> 00:21:55,390
+ال healthلكل ال health professions لأن هو بتعامل
+
+291
+00:21:55,390 --> 00:21:59,130
+مع صحة الإنسان عشان يتعامل مع صحة الإنسان هذا لازم
+
+292
+00:21:59,130 --> 00:22:03,670
+يكون معرفة بتشريح أعضاء الإنسان وبهيك ان شاء الله
+
+293
+00:22:03,670 --> 00:22:07,070
+نلتقي معاكم في مساقات أخرى ويعطيكم العافية
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..769d1d18527d0c23b3424b0b278ff72b1437f2f9
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E_raw.json
@@ -0,0 +1 @@
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"end": 1278.21, "word": " ال", "probability": 0.57666015625}, {"start": 1278.21, "end": 1278.45, "word": " brand", "probability": 0.90234375}, {"start": 1278.45, "end": 1278.71, "word": " لأن", "probability": 0.787353515625}, {"start": 1278.71, "end": 1278.79, "word": " ال", "probability": 0.97412109375}, {"start": 1278.79, "end": 1279.01, "word": " brand", "probability": 0.91357421875}, {"start": 1279.01, "end": 1279.45, "word": " ماكنش", "probability": 0.4896647135416667}, {"start": 1279.45, "end": 1280.15, "word": " مكتمل", "probability": 0.84722900390625}], "temperature": 1.0}, {"id": 59, "seek": 129401, "start": 1280.51, "end": 1294.01, "text": "نقوم بهذه احنا بنكون أنهينا محاضراتنا لفي مساق ال anatomy وانا بتمنى ان يكونوا وجودي معاكم ساعتكم في الفترة السابقة في خلينا نقول", "tokens": [1863, 4587, 20498, 39627, 24192, 1975, 5016, 8315, 44945, 30544, 14739, 3224, 1829, 8315, 3714, 5016, 46958, 2288, 9307, 8315, 5296, 41185, 47524, 995, 4587, 2423, 31566, 4032, 7649, 995, 39894, 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{"start": 1286.51, "end": 1286.89, "word": " ال", "probability": 0.4755859375}, {"start": 1286.89, "end": 1287.51, "word": " anatomy", "probability": 0.6953125}, {"start": 1287.51, "end": 1288.33, "word": " وانا", "probability": 0.7736002604166666}, {"start": 1288.33, "end": 1288.81, "word": " بتمنى", "probability": 0.8868815104166666}, {"start": 1288.81, "end": 1288.97, "word": " ان", "probability": 0.7880859375}, {"start": 1288.97, "end": 1289.37, "word": " يكونوا", "probability": 0.7394205729166666}, {"start": 1289.37, "end": 1289.79, "word": " وجودي", "probability": 0.73828125}, {"start": 1289.79, "end": 1290.27, "word": " معاكم", "probability": 0.982421875}, {"start": 1290.27, "end": 1290.91, "word": " ساعتكم", "probability": 0.788330078125}, {"start": 1290.91, "end": 1291.09, "word": " في", "probability": 0.91943359375}, {"start": 1291.09, "end": 1291.45, "word": " الفترة", "probability": 0.98974609375}, {"start": 1291.45, "end": 1292.15, "word": " السابقة", "probability": 0.9915364583333334}, {"start": 1292.15, "end": 1292.91, "word": " في", "probability": 0.810546875}, {"start": 1292.91, "end": 1293.39, "word": " خلينا", "probability": 0.8028157552083334}, {"start": 1293.39, "end": 1294.01, "word": " نقول", "probability": 0.994873046875}], "temperature": 1.0}, {"id": 60, "seek": 131032, "start": 1296.0, "end": 1310.32, "text": "يعني وضع بعض اللمسات أو التركيز على بعض النقاط اللي لازم احنا نحفظها و لازم احنا نعرفها في مجال ال Anatomy Online لأن لمساق ال Anatomy ممثقة كتير مهمة للناس اللي بتدرس ال health", "tokens": [40228, 22653, 4032, 11242, 3615, 45030, 11242, 13672, 2304, 3794, 9307, 34051, 16712, 31747, 1829, 11622, 15844, 45030, 11242, 28239, 4587, 41193, 13672, 1829, 5296, 31377, 2304, 1975, 5016, 8315, 8717, 5016, 5172, 19913, 11296, 4032, 5296, 31377, 2304, 1975, 5016, 8315, 8717, 3615, 28480, 11296, 8978, 3714, 7435, 6027, 2423, 42628, 8488, 16930, 5296, 33456, 32767, 3794, 995, 4587, 2423, 42628, 8488, 3714, 2304, 12984, 28671, 9122, 2655, 13546, 3714, 16095, 3660, 24976, 8315, 3794, 13672, 1829, 39894, 3215, 2288, 3794, 2423, 1585], "avg_logprob": -0.14715074090396657, "compression_ratio": 1.620879120879121, "no_speech_prob": 1.430511474609375e-06, "words": [{"start": 1296.0, "end": 1296.48, "word": "يعني", "probability": 0.810302734375}, {"start": 1296.48, "end": 1296.98, "word": " وضع", "probability": 0.9601236979166666}, {"start": 1296.98, "end": 1297.38, "word": " بعض", "probability": 0.948486328125}, {"start": 1297.38, "end": 1298.38, "word": " اللمسات", "probability": 0.943359375}, {"start": 1298.38, "end": 1298.86, "word": " أو", "probability": 0.8603515625}, {"start": 1298.86, "end": 1300.04, "word": " التركيز", "probability": 0.98486328125}, {"start": 1300.04, "end": 1300.2, "word": " على", "probability": 0.77490234375}, {"start": 1300.2, "end": 1300.46, "word": " بعض", "probability": 0.988525390625}, {"start": 1300.46, "end": 1300.92, "word": " النقاط", "probability": 0.9285481770833334}, {"start": 1300.92, "end": 1301.04, "word": " اللي", "probability": 0.9697265625}, {"start": 1301.04, "end": 1301.32, "word": " لازم", "probability": 0.99267578125}, {"start": 1301.32, "end": 1301.52, "word": " احنا", "probability": 0.8621419270833334}, {"start": 1301.52, "end": 1302.08, "word": " نحفظها", "probability": 0.97646484375}, {"start": 1302.08, "end": 1302.22, "word": " و", "probability": 0.828125}, {"start": 1302.22, "end": 1302.54, "word": " لازم", "probability": 0.9440104166666666}, {"start": 1302.54, "end": 1302.94, "word": " احنا", "probability": 0.96533203125}, {"start": 1302.94, "end": 1303.82, "word": " نعرفها", "probability": 0.9854736328125}, {"start": 1303.82, "end": 1304.0, "word": " في", "probability": 0.9306640625}, {"start": 1304.0, "end": 1304.38, "word": " مجال", "probability": 0.8567708333333334}, {"start": 1304.38, "end": 1304.5, "word": " ال", "probability": 0.9599609375}, {"start": 1304.5, "end": 1304.96, "word": " Anatomy", "probability": 0.644287109375}, {"start": 1304.96, "end": 1305.24, "word": " Online", "probability": 0.396240234375}, {"start": 1305.24, "end": 1305.92, "word": " لأن", "probability": 0.61279296875}, {"start": 1305.92, "end": 1306.4, "word": " لمساق", "probability": 0.7724609375}, {"start": 1306.4, "end": 1306.5, "word": " ال", "probability": 0.9248046875}, {"start": 1306.5, "end": 1306.84, "word": " Anatomy", "probability": 0.9482421875}, {"start": 1306.84, "end": 1307.38, "word": " ممثقة", "probability": 0.582611083984375}, {"start": 1307.38, "end": 1307.78, "word": " كتير", "probability": 0.93359375}, {"start": 1307.78, "end": 1308.46, "word": " مهمة", "probability": 0.95166015625}, {"start": 1308.46, "end": 1309.18, "word": " للناس", "probability": 0.8352864583333334}, {"start": 1309.18, "end": 1309.28, "word": " اللي", "probability": 0.979736328125}, {"start": 1309.28, "end": 1309.76, "word": " بتدرس", "probability": 0.98583984375}, {"start": 1309.76, "end": 1309.88, "word": " ال", "probability": 0.98876953125}, {"start": 1309.88, "end": 1310.32, "word": " health", "probability": 0.703125}], "temperature": 1.0}, {"id": 61, "seek": 132707, "start": 1312.21, "end": 1327.07, "text": "لكل ال health professions لأن هو بتعامل مع صحة الإنسان عشان يتعامل مع صحة الإنسان هذا لازم يكون معرفة بتشريح أعضاء الإنسان وبهيك ان شاء الله نلتقي معاكم في مساقات أخرى ويعطيكم العافية", "tokens": [1211, 28820, 2423, 1585, 38129, 5296, 33456, 31439, 39894, 3615, 10943, 1211, 20449, 20328, 5016, 3660, 33688, 1863, 3794, 7649, 6225, 8592, 7649, 7251, 2655, 3615, 10943, 1211, 20449, 20328, 5016, 3660, 33688, 1863, 3794, 7649, 23758, 5296, 31377, 2304, 7251, 30544, 20449, 28480, 3660, 39894, 8592, 16572, 5016, 5551, 3615, 11242, 16606, 33688, 1863, 3794, 7649, 46599, 3224, 1829, 4117, 16472, 13412, 16606, 21984, 8717, 1211, 2655, 38436, 20449, 995, 24793, 8978, 47524, 995, 4587, 9307, 5551, 34740, 7578, 4032, 40228, 9566, 1829, 24793, 18863, 31845, 10632], "avg_logprob": -0.1495786490065328, "compression_ratio": 1.7043010752688172, "no_speech_prob": 0.00024247169494628906, "words": [{"start": 1312.21, "end": 1313.05, "word": "لكل", "probability": 0.6136474609375}, {"start": 1313.05, "end": 1313.19, "word": " ال", "probability": 0.95947265625}, {"start": 1313.19, "end": 1313.39, "word": " health", "probability": 0.66162109375}, {"start": 1313.39, "end": 1314.11, "word": " professions", "probability": 0.9287109375}, {"start": 1314.11, "end": 1314.53, "word": " لأن", "probability": 0.73388671875}, {"start": 1314.53, "end": 1314.77, "word": " هو", "probability": 0.5048828125}, {"start": 1314.77, "end": 1315.39, "word": " بتعامل", "probability": 0.85430908203125}, {"start": 1315.39, "end": 1315.55, "word": " مع", "probability": 0.96337890625}, {"start": 1315.55, "end": 1315.93, "word": " صحة", "probability": 0.97412109375}, {"start": 1315.93, "end": 1316.55, "word": " الإنسان", "probability": 0.9844970703125}, {"start": 1316.55, "end": 1316.89, "word": " عشان", "probability": 0.9083658854166666}, {"start": 1316.89, "end": 1317.31, "word": " يتعامل", "probability": 0.871337890625}, {"start": 1317.31, "end": 1317.47, "word": " مع", "probability": 0.9931640625}, {"start": 1317.47, "end": 1317.81, "word": " صحة", "probability": 0.984375}, {"start": 1317.81, "end": 1318.23, "word": " الإنسان", "probability": 0.9945068359375}, {"start": 1318.23, "end": 1318.49, "word": " هذا", "probability": 0.74853515625}, {"start": 1318.49, "end": 1319.13, "word": " لازم", "probability": 0.7394205729166666}, {"start": 1319.13, "end": 1319.43, "word": " يكون", "probability": 0.895751953125}, {"start": 1319.43, "end": 1319.99, "word": " معرفة", "probability": 0.9890950520833334}, {"start": 1319.99, "end": 1320.73, "word": " بتشريح", "probability": 0.96044921875}, {"start": 1320.73, "end": 1321.49, "word": " أعضاء", "probability": 0.94189453125}, {"start": 1321.49, "end": 1322.65, "word": " الإنسان", "probability": 0.9949951171875}, {"start": 1322.65, "end": 1323.37, "word": " وبهيك", "probability": 0.70263671875}, {"start": 1323.37, "end": 1323.47, "word": " ان", "probability": 0.64990234375}, {"start": 1323.47, "end": 1323.63, "word": " شاء", "probability": 0.94921875}, {"start": 1323.63, "end": 1323.67, "word": " الله", "probability": 0.95556640625}, {"start": 1323.67, "end": 1324.11, "word": " نلتقي", "probability": 0.9398193359375}, {"start": 1324.11, "end": 1324.53, "word": " معاكم", "probability": 0.8274739583333334}, {"start": 1324.53, "end": 1324.79, "word": " في", "probability": 0.94384765625}, {"start": 1324.79, "end": 1325.47, "word": " مساقات", "probability": 0.9112548828125}, {"start": 1325.47, "end": 1325.97, "word": " أخرى", "probability": 0.97705078125}, {"start": 1325.97, "end": 1326.57, "word": " ويعطيكم", "probability": 0.801220703125}, {"start": 1326.57, "end": 1327.07, "word": " العافية", "probability": 0.9620768229166666}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1327.53125, "duration_after_vad": 1307.676875}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..0ce245f04a2c3bbe60d014fba7a81b7503edb063
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/rAhX1TP-i5E_raw.srt
@@ -0,0 +1,1176 @@
+1
+00:00:04,990 --> 00:00:09,290
+بسم الله الرحمن الرحيم محاضرتنا اليوم الأخيرة في
+
+2
+00:00:09,290 --> 00:00:14,590
+مساقر ال anatomy هنتكلم فيها عن الجزء الأخر من ال
+
+3
+00:00:14,590 --> 00:00:18,010
+nervous system وهو ال spinal cord المحاضرة السابقة
+
+4
+00:00:18,010 --> 00:00:22,630
+كانت بتتكلم عن ال brain وقلنا امتداد لل brain في
+
+5
+00:00:22,630 --> 00:00:26,740
+ال central nervous system هو ال spinal cordوهو
+
+6
+00:00:26,740 --> 00:00:30,640
+وظيفته إنه يعمل link between the body regions and
+
+7
+00:00:30,640 --> 00:00:36,040
+the brain طبعا هو ممكن يكون فيه عنده بعض ال
+
+8
+00:00:36,040 --> 00:00:39,540
+functional independency عن ال brain زي موضوع ال
+
+9
+00:00:39,540 --> 00:00:44,000
+reflexes ال spinal cord و ال spinal nerves serve
+
+10
+00:00:44,000 --> 00:00:49,240
+two functions أول حاجة ال pathway for sensory and
+
+11
+00:00:49,240 --> 00:00:54,470
+motor impulses وكمان responsible of thereflexes طب
+
+12
+00:00:54,470 --> 00:00:57,830
+كيفي ال pathway من ال sensory؟ لأن احنا لما نبقى
+
+13
+00:00:57,830 --> 00:01:02,270
+ماشيين و احنا ماشيين بتعتر بحجر او بيغزنا دبوس كيف
+
+14
+00:01:02,270 --> 00:01:05,770
+بنعرف انه احنا هذا الدبوس غزنا و بنشرد رجلنا هذا
+
+15
+00:01:05,770 --> 00:01:08,890
+ال reflex لكن بيصير interpretation لل impulse هذه
+
+16
+00:01:08,890 --> 00:01:13,760
+as a sensory impulse بتروحمن الفوت عبر الـ spinal
+
+17
+00:01:13,760 --> 00:01:18,660
+cord على الدماغ والإشارة بتيجي كمان من الدماغ لإن
+
+18
+00:01:18,660 --> 00:01:23,460
+إحنا حاسين تحتنا حجر بنرفع رجلنا أو عينا حفرة
+
+19
+00:01:23,460 --> 00:01:27,460
+بنتدرك الأمر لإنه بيطلع الأمر على ال brain بعمل
+
+20
+00:01:27,460 --> 00:01:31,680
+interpretation وبعت ال order المناسب لعضلاتنا عشان
+
+21
+00:01:31,680 --> 00:01:35,280
+تتحرك في الاتجاه المناسب
+
+22
+00:01:37,280 --> 00:01:42,520
+كمان ال .. ال .. ال spinal .. ال spinal cord فيه
+
+23
+00:01:42,520 --> 00:01:47,200
+له تقريبا احنا حكينا عن حجم ال brain اليوم بنتكلم
+
+24
+00:01:47,200 --> 00:01:51,180
+عن طول ال spinal cord لإن هو عبارة عن قناة طويلة
+
+25
+00:01:51,180 --> 00:01:58,460
+بتبدأ من أسفل الرقبة و بتنتهي في الظهرطبعا هذه
+
+26
+00:01:58,460 --> 00:02:01,040
+بتاخد تقريبا اتنين و أربعين لخمسة و أربعين
+
+27
+00:02:01,040 --> 00:02:06,100
+centimeter على حسب الطول و هي عبارة عن cylinder
+
+28
+00:02:06,100 --> 00:02:12,900
+عبارة عن قنا cylindrical شاب طبعا إلها بعض ال
+
+29
+00:02:12,900 --> 00:02:17,620
+flattened anterior and posterior في إلها ال
+
+30
+00:02:17,620 --> 00:02:20,200
+depressions
+
+31
+00:02:20,800 --> 00:02:24,520
+في الدورسل وفي عندنا ال ventral أو هو الدورسل ال
+
+32
+00:02:24,520 --> 00:02:27,580
+posterior و ال ventral هو ال anterior median
+
+33
+00:02:27,580 --> 00:02:28,440
+facial
+
+34
+00:02:32,300 --> 00:02:37,920
+هي شكل ال .. ال cross-sectional .. ال sectional
+
+35
+00:02:37,920 --> 00:02:43,800
+view بيعطينا زي ما احنا شايفين شكل ال spinal cord
+
+36
+00:02:43,800 --> 00:02:47,320
+في ال anterior horn، في عندنا ال posterior horn،
+
+37
+00:02:47,320 --> 00:02:50,500
+في عندنا ال median fissure اللي اتكلمنا عنه قبل
+
+38
+00:02:50,500 --> 00:02:56,960
+شوية، في عندناال sulcus ال posterior sulcusي بهذا
+
+39
+00:02:56,960 --> 00:03:03,140
+الشكل طبعا في عندنا ال dorsal spinal nerve road و
+
+40
+00:03:03,140 --> 00:03:08,760
+في عندنا ال dorsal ganglia هنشوفهم واحد و واحد في
+
+41
+00:03:08,760 --> 00:03:14,080
+ال structure ال spinal cord في عندنا كذا region في
+
+42
+00:03:14,080 --> 00:03:17,880
+عندنا cervical و في عندنا lumbar و في عندنا sacral
+
+43
+00:03:18,240 --> 00:03:22,020
+الكوكسيجيال، طبعا ال cervical هي عبارة عن ال
+
+44
+00:03:22,020 --> 00:03:26,200
+continuation للمدلة longata وفيها eight spinal
+
+45
+00:03:26,200 --> 00:03:32,280
+nerves أما thoracic فهي عبارة عن twelve pairs of
+
+46
+00:03:32,280 --> 00:03:37,200
+spinal أو thoracic spinal nerve وفي عندنا five
+
+47
+00:03:37,200 --> 00:03:41,680
+lumbarSpinal nerve وفى عندنا five sacral spinal
+
+48
+00:03:41,680 --> 00:03:46,800
+nerve وفى عندنا only one coccygeal spinal nerve
+
+49
+00:03:46,800 --> 00:03:51,540
+وهدولة مجموعة بيكون واحد و تلاتين pairs of spinal
+
+50
+00:03:51,540 --> 00:03:55,420
+nerve زى ما احنا شايفينهم بالرسم التوضيحى هذا
+
+51
+00:03:55,420 --> 00:03:58,760
+عندنا تمانية cervical عندنا twelve thoracic عندنا
+
+52
+00:03:58,760 --> 00:04:02,620
+five lumbar وعندنا five sacral و only one
+
+53
+00:04:02,620 --> 00:04:09,130
+coccygealزي ما احنا شايفين في الصورة طبعا ال
+
+54
+00:04:09,130 --> 00:04:13,990
+spinal cord فيله تلت أجزاء هو shorter than the
+
+55
+00:04:13,990 --> 00:04:17,050
+vertebral canal ال vertebral canal اللي قولنا
+
+56
+00:04:17,050 --> 00:04:22,670
+بتنتهي في نهاية الcoccyx لكن ال spinal cord بنتهي
+
+57
+00:04:22,670 --> 00:04:27,490
+على ال tube طبعا في عندنا ال conus medialaris هي
+
+58
+00:04:27,490 --> 00:04:33,280
+ال tabard المدققة خلنا نقول بتبدأ يتبوز فيهاالـ
+
+59
+00:04:33,280 --> 00:04:36,880
+inferior end of the spinal cord وmark of the
+
+60
+00:04:36,880 --> 00:04:40,980
+official end of the spinal cord proper بنتهي عندها
+
+61
+00:04:40,980 --> 00:04:45,000
+ال spinal cord وفي عندها بعدها بتيجي الكودة equina
+
+62
+00:04:45,000 --> 00:04:49,460
+هي عبارة عن مجموعة nerve roots group of axon
+
+63
+00:04:49,460 --> 00:04:53,680
+project inferiorly from the spinal cord هي تحت
+
+64
+00:04:53,680 --> 00:04:58,680
+الkonus medullaris وفي عندنا في نهاية ال filament
+
+65
+00:04:58,680 --> 00:05:00,860
+ال film terminal
+
+66
+00:05:13,400 --> 00:05:17,140
+والخلل في القودا إيكوينا تعتبر lower motor neuron
+
+67
+00:05:17,140 --> 00:05:22,000
+lesion أما أي خلل في الـ spinalأو Damage لـ Spinal
+
+68
+00:05:22,000 --> 00:05:26,220
+Corp فوق ال code Aquina فهي Upper Motor Neuron
+
+69
+00:05:26,220 --> 00:05:32,080
+Lesion وهذا كتير مهم في تحديد نوع ال motor ال
+
+70
+00:05:32,080 --> 00:05:35,680
+neuron lesion اللي معاشورة طبعا في عندنا Spinal
+
+71
+00:05:35,680 --> 00:05:41,150
+meninges هم اللي اتكلمنا عنهم احناالسيد اتكلمنا عن
+
+72
+00:05:41,150 --> 00:05:44,830
+في ال brain في عندنا three meninges في ال durable
+
+73
+00:05:44,830 --> 00:05:49,750
+matter وفي ال arachnoid وفي ال biomatter وفي هدولة
+
+74
+00:05:49,750 --> 00:05:53,410
+نفسهم اللي هم continuation على ال spinal cord هي
+
+75
+00:05:53,410 --> 00:05:59,550
+عبارة عن continuous of cranial meningesطبعا ال
+
+76
+00:05:59,550 --> 00:06:04,250
+structure that in .. that encircle the spinal cord
+
+77
+00:06:04,250 --> 00:06:08,110
+ناخده من ال superficial لديه في ال .. في ال
+
+78
+00:06:08,110 --> 00:06:11,130
+superficial مصدفة ال superficial هي ال bones of
+
+79
+00:06:11,130 --> 00:06:15,690
+vertebra و بعدين في عندنا ال epidural space و
+
+80
+00:06:15,690 --> 00:06:20,370
+بعدين دي الدورة المطر اللي بنسميها الأم الجافية و
+
+81
+00:06:20,370 --> 00:06:24,190
+بعدين ال subdural spaceوفي عندنا ال arachnoid وفي
+
+82
+00:06:24,190 --> 00:06:28,130
+عندنا ال subdural هي subarachnoid space وفي نهاية
+
+83
+00:06:28,130 --> 00:06:32,590
+ال biomatter اللي هي الأم الحنون اللي بتكون ملاسقة
+
+84
+00:06:32,590 --> 00:06:39,290
+لل spinal cord وهي زي ما احنا شايفينهم بالرسم،
+
+85
+00:06:39,290 --> 00:06:43,450
+الرسم ماضي فيها عندنا ال spinal cordفي المنتصف
+
+86
+00:06:43,450 --> 00:06:49,770
+وبيبدأ من البيامتر هي اول level هي هنا ال spinal
+
+87
+00:06:49,770 --> 00:06:54,290
+cord بعدين البيامتر و بعدين ال subarachnoid و
+
+88
+00:06:54,290 --> 00:07:00,810
+بعدين ال arachnoid و بعدين بنروح لديورة و نقلب
+
+89
+00:07:00,810 --> 00:07:04,630
+ديورة ال space اللي هو فوق الديورة و بنتهيأ هنا
+
+90
+00:07:04,630 --> 00:07:10,550
+بالبالعضمة اللي هي ال vertebra نفسها و هنا بتبدأ
+
+91
+00:07:10,550 --> 00:07:14,050
+ال spinal nerve
+
+92
+00:07:14,050 --> 00:07:19,430
+تظهر و في زي ما احنا شايفين اللي بتطلع ال spinal
+
+93
+00:07:19,430 --> 00:07:23,370
+nerve من ال intervertebral foramen و زي ما احنا
+
+94
+00:07:23,370 --> 00:07:27,030
+شايفين هنا في عندنا ال anterior part of the
+
+95
+00:07:27,030 --> 00:07:30,210
+vertebra اللي هو ال body و ال posterior part اللي
+
+96
+00:07:30,210 --> 00:07:34,710
+هو ال spines و ال transverse process of the spine
+
+97
+00:07:37,330 --> 00:07:42,150
+وهذا الشكل برضه بيوضح بالظبط أنها الـ Deuterometer
+
+98
+00:07:42,150 --> 00:07:47,050
+وفي عندنا الاركنويد
+
+99
+00:07:47,050 --> 00:07:51,390
+وفي عندنا هذا الـ Delicate sheet اللي هو اللي بيها
+
+100
+00:07:51,390 --> 00:07:55,540
+متر وزي ما احنا شايفين في عندناعدد من ال blood
+
+101
+00:07:55,540 --> 00:08:01,680
+vessels و كانت arteries او دين عشان تغذي ال spinal
+
+102
+00:08:01,680 --> 00:08:07,200
+cord وهنا شايفين ال posterior و ال spinal nerve
+
+103
+00:08:07,200 --> 00:08:11,360
+كيف بياخد ال anterior root و ال posterior root و
+
+104
+00:08:11,360 --> 00:08:16,820
+بتحدوا مع بعض و بتلعن ال spinal nerveطبعا ال
+
+105
+00:08:16,820 --> 00:08:20,740
+spinal nerve عبارة عن ال 31 pairs of spinal nerve
+
+106
+00:08:20,740 --> 00:08:27,160
+connect ال central nervous system to receptors و
+
+107
+00:08:27,160 --> 00:08:31,400
+ال muscle and gland، each spinal nerve بيكون mixed
+
+108
+00:08:31,400 --> 00:08:34,600
+لإن في عندنا motor، في عندنا sensory، ال motor
+
+109
+00:08:34,600 --> 00:08:40,460
+بيجيب ال order من ال brain لspinal cord و لأجزاء
+
+110
+00:08:40,460 --> 00:08:45,910
+ال bodyوالعكس الـ sensory بياخد من أجزاء ال body
+
+111
+00:08:45,910 --> 00:08:49,230
+إلى ال spinal cord ثم إلى ال brain for
+
+112
+00:08:49,230 --> 00:08:52,570
+interpretation ال sensory axon originated from
+
+113
+00:08:52,570 --> 00:08:57,690
+receptors و ال motor axon originated from the
+
+114
+00:08:57,690 --> 00:09:02,150
+spinal cord في أن ال anterior and posterior root
+
+115
+00:09:02,460 --> 00:09:06,320
+وهذا البرامج تصبح جزء من البرامج التجاربية البرامج
+
+116
+00:09:06,320 --> 00:09:09,380
+التجاربية البرامج التجاربية البرامج التجاربية
+
+117
+00:09:09,380 --> 00:09:11,160
+البرامج التجاربية البرامج التجاربية البرامج
+
+118
+00:09:11,160 --> 00:09:12,900
+التجاربية البرامج التجاربية البرامج التجاربية
+
+119
+00:09:12,900 --> 00:09:16,320
+البرامج التجاربية البرامج التجاربية البرامج
+
+120
+00:09:16,320 --> 00:09:19,060
+التجاربية البرامج التجاربية البرامج التجاربية
+
+121
+00:09:19,060 --> 00:09:20,020
+البرامج التجاربية البرامج التجاربية البرامج
+
+122
+00:09:20,020 --> 00:09:25,340
+التجاربيةرامي of spinal nerve of spinal nerve في
+
+123
+00:09:25,340 --> 00:09:28,100
+عندنا ال posterior or dorsal ramus اللي هو
+
+124
+00:09:28,100 --> 00:09:31,460
+innervate ال muscle and skin of the back وفي عندنا
+
+125
+00:09:31,460 --> 00:09:34,600
+ال ventral ramus او ال anterior ramus هي ال
+
+126
+00:09:34,600 --> 00:09:37,320
+largest branch وبيتكومل ال plexus اللي عندنا
+
+127
+00:09:37,320 --> 00:09:41,240
+هنتكلم عنهمو innervate ال anterior and lateral
+
+128
+00:09:41,240 --> 00:09:43,960
+trunk of the upper and lower limb يبقى ال
+
+129
+00:09:43,960 --> 00:09:47,140
+posterior اللي علاقة بال skin and muscle of the
+
+130
+00:09:47,140 --> 00:09:52,040
+back أما ال anterior لل upper and lower limb و هذا
+
+131
+00:09:52,040 --> 00:09:57,030
+الكلام مهم جدا إحنا نحفظه و نفهمهفينا الـ dorsal
+
+132
+00:09:57,030 --> 00:10:00,030
+root اللي هي posterior or sensorial root وفينا الـ
+
+133
+00:10:00,030 --> 00:10:03,910
+ventral root اللي هي الـ anterior root يبقى ال
+
+134
+00:10:03,910 --> 00:10:09,870
+motor ال anterior هي عبارة عن motor axons أما ال
+
+135
+00:10:09,870 --> 00:10:15,970
+posterior فهي sensory axons ال posterior axon of
+
+136
+00:10:15,970 --> 00:10:19,170
+sensor neuron in the dorsal root أما ال ventral
+
+137
+00:10:19,170 --> 00:10:23,260
+فهي axon of motor neuronscells body are in the
+
+138
+00:10:23,260 --> 00:10:26,400
+spinal cord في أن الـdorsal root كان كلها cell
+
+139
+00:10:26,400 --> 00:10:29,900
+body of sensor neurons whose acts on conduct
+
+140
+00:10:29,900 --> 00:10:33,280
+impulse inward from the peripheral of the body
+
+141
+00:10:33,280 --> 00:10:36,840
+بتاخد من ال peripheral of the body وفي أن ال
+
+142
+00:10:36,840 --> 00:10:42,980
+spinal nerve هي عبارة عن اتحاد ال ventral و ال
+
+143
+00:10:42,980 --> 00:10:47,360
+dorsal roots عشان يطلع أنها ال spinal nerve وقولنا
+
+144
+00:10:47,360 --> 00:10:50,460
+كل spinal nerve فيها sensory and motor
+
+145
+00:10:54,180 --> 00:10:58,320
+هذا الرسم التوضيحي بوضح لنا كيف بيصير الـ dorsal
+
+146
+00:10:58,320 --> 00:11:04,380
+root ganglia وفي عندنا هنا ال ventral branch اللي
+
+147
+00:11:04,380 --> 00:11:07,220
+ال spinal cord او ال ventral رعمي و زي ما نشايفين
+
+148
+00:11:07,220 --> 00:11:12,520
+احنا ال dorsal او ال posterior الرعمي واتحادهم
+
+149
+00:11:12,520 --> 00:11:18,600
+اللي هو بيطلع عندنا ال spinal ال spinal cord ال
+
+150
+00:11:18,600 --> 00:11:20,980
+spinal nerve اسمها ال spinal nerve
+
+151
+00:11:23,710 --> 00:11:28,730
+طب نروح لحاجة اسمها ال dermatones ال dermatones هي
+
+152
+00:11:28,730 --> 00:11:34,550
+عبارة عن specific segment of the skin supplied by
+
+153
+00:11:34,550 --> 00:11:39,770
+single spinal nerve all spinal nerves innervate a
+
+154
+00:11:39,770 --> 00:11:42,710
+segment of the skin and associated with the
+
+155
+00:11:42,710 --> 00:11:48,080
+dermatomeExcept C1، C1 ما .. ما .. مالوش ديرماتون
+
+156
+00:11:48,080 --> 00:11:51,740
+الـ Dermatons map هي عبارة عن sensory segment skin
+
+157
+00:11:51,740 --> 00:11:55,320
+of the body associated with the spinal nerve و هذه
+
+158
+00:11:55,320 --> 00:11:59,260
+ال map اللي احنا بنحب دائما نصورها و نحطها في
+
+159
+00:11:59,260 --> 00:12:05,010
+مراكزنا و أقصرنا حتى ماكن بس بنحفظلأنه هان بتحددنا
+
+160
+00:12:05,010 --> 00:12:10,350
+زي ما شايفين الإحساس في كل مكان وكل منطقة من الجسم
+
+161
+00:12:10,350 --> 00:12:13,390
+زي ما احنا شايفين منطقة ال thumb هنا في ال
+
+162
+00:12:13,390 --> 00:12:17,670
+anterior part C6
+
+163
+00:12:17,670 --> 00:12:22,050
+مثلا و في ال posterior part of the thumb برضه C6،
+
+164
+00:12:22,050 --> 00:12:27,510
+C7 مثلا في ال posterior part في ال index و ال
+
+165
+00:12:27,510 --> 00:12:31,010
+third finger
+
+166
+00:12:32,160 --> 00:12:39,020
+وشايفين كمان هنا ال C8 مثلا هي في ال fourth و ال
+
+167
+00:12:39,020 --> 00:12:44,180
+fifth finger و زي ما احنا شايفين هنا كل جزء من
+
+168
+00:12:44,180 --> 00:12:50,290
+الجسم على الجلد فيه بيغزي منطقةمعينة من الـ spinal
+
+169
+00:12:50,290 --> 00:12:53,750
+nerve زي ما شايفين مثلا S1 هنا ع ال lateral part
+
+170
+00:12:53,750 --> 00:12:58,490
+of the .. of the foot مع ال little finger و هان
+
+171
+00:12:58,490 --> 00:13:06,910
+برضه شايفين بالخلف S1 و S2 و هكذا فهذا كله بيوضحها
+
+172
+00:13:06,910 --> 00:13:11,890
+ال mapping تبعت ال sensory أو dermatomes of the
+
+173
+00:13:11,890 --> 00:13:16,650
+sensory nerveهنا في حاجة اسمها Intercostal nerves
+
+174
+00:13:16,650 --> 00:13:21,410
+هي عبارة عن الانتررومي of spinal nerves من T1 ل
+
+175
+00:13:21,410 --> 00:13:27,770
+T11 تترفل في الاسبس تعمل عاملة زي ساندويش between
+
+176
+00:13:27,770 --> 00:13:32,750
+two adjacent vertebra هدول اللي احنا شايفينهم
+
+177
+00:13:32,750 --> 00:13:35,510
+بالرسم Spinal nerve
+
+178
+00:13:40,700 --> 00:13:45,560
+طبعا في حاجة اسمها if plexus ال .. في عندنا أربعة
+
+179
+00:13:45,560 --> 00:13:49,460
+measure of plexuses أو principle ال nerve plexus
+
+180
+00:13:49,460 --> 00:13:56,340
+هي a network of a inter waving anterior rami of
+
+181
+00:13:56,340 --> 00:14:00,640
+the spinal nerve ال nerve plexuses بتقولنا لإن
+
+182
+00:14:00,640 --> 00:14:04,520
+احنا ال anterior rami هي المسؤولة عن ال upper and
+
+183
+00:14:04,520 --> 00:14:08,380
+lower limb و هدولة ال plexuses بتغضي ال upper and
+
+184
+00:14:08,380 --> 00:14:12,210
+lowerالنيرف بليكساس على جميع الجانب اليسرى و
+
+185
+00:14:12,210 --> 00:14:16,930
+اليسرى من الجسم نيرف بليكساس مختلط إلى عدد من
+
+186
+00:14:16,930 --> 00:14:20,610
+النام نيرف يعني عدد من النار التي تدخل الفيروس و
+
+187
+00:14:20,610 --> 00:14:24,610
+أسلوب الجسم سنأخذ منهم البنصيبلز اللي هو
+
+188
+00:14:24,610 --> 00:14:28,910
+الcervical plexus و الbrachial plexus هدولة للأعلى
+
+189
+00:14:28,910 --> 00:14:32,130
+اللمب و في ال lumbar plexus و ال sacral plexus
+
+190
+00:14:32,130 --> 00:14:37,600
+للأعلى اللمبفي حاجة اسمها Reflexes هذي Fast
+
+191
+00:14:37,600 --> 00:14:42,920
+Stereotype Inborn Protective Actions طبعا يعني هي
+
+192
+00:14:42,920 --> 00:14:49,380
+عبارة عن حركات لا إيرادية سريعة نمطية بتساعد على
+
+193
+00:14:49,380 --> 00:14:52,900
+حماية الجسم هذا اللي بتصير لما احنا بنلمس أي إش
+
+194
+00:14:52,900 --> 00:14:56,800
+ثقون فبنهرب إيدنا بشكنا دبوس فعالسريع احنا بنسحب
+
+195
+00:14:56,800 --> 00:15:03,790
+إيدنا أو رجلنا بنتعرض مثلا لأي مخاطرة أوأو مثلا
+
+196
+00:15:03,790 --> 00:15:10,030
+نار بندعس على نار أو غيره فبتلاقي فورا بت .. بنشرد
+
+197
+00:15:10,030 --> 00:15:14,590
+إيدنا أو رجلنا عن المكان or care at the spinal
+
+198
+00:15:14,590 --> 00:15:18,490
+cord and brain stem level maybe eithermono
+
+199
+00:15:18,490 --> 00:15:22,950
+-synaptic أو poly-synaptic طبعا كله بيحتاج all
+
+200
+00:15:22,950 --> 00:15:26,270
+-equal stimulus at receptors بتصير stimulation
+
+201
+00:15:26,270 --> 00:15:30,130
+للـreceptors الموجودة في المكان على طول بتعمل
+
+202
+00:15:30,130 --> 00:15:34,070
+sensory information relay بتوصل هذه الinformation
+
+203
+00:15:34,070 --> 00:15:38,470
+processing at the level ال central nervous system
+
+204
+00:15:38,470 --> 00:15:41,990
+بتروح ال central nervous system على ال brain على
+
+205
+00:15:41,990 --> 00:15:44,730
+ال spinal cord أو بتطلع على ال brain stem و
+
+206
+00:15:44,730 --> 00:15:47,370
+activation of the motor response عشان أنه احنا
+
+207
+00:15:47,680 --> 00:15:51,880
+انهرب ايدنا او رجلنا من المكان و بيصير في عندنا
+
+208
+00:15:51,880 --> 00:15:56,620
+response ال peripheral effector سواء كانت ال
+
+209
+00:15:56,620 --> 00:16:00,640
+muscles or ال glands طبعا بنحتاج هنا receptors و
+
+210
+00:16:00,640 --> 00:16:02,660
+في عندنا afferent neurons ال receptors هي
+
+211
+00:16:02,660 --> 00:16:07,180
+المستقبلات للألم او لالإحساس هذا الـ Afferent
+
+212
+00:16:07,180 --> 00:16:12,560
+neurons هي اللي بتروح من ال periphery إلى ال
+
+213
+00:16:12,560 --> 00:16:16,380
+central nervous system نحتاج ل integration تفسير
+
+214
+00:16:16,380 --> 00:16:21,940
+لهذا الموضوع الترجمة في ال central nervous system
+
+215
+00:16:21,940 --> 00:16:25,820
+وفي عندنا ال afferent neuronsاللي هي ال .. ال ..
+
+216
+00:16:25,820 --> 00:16:30,460
+ال neurose المسؤولة عن تنزيل ال .. المعلومة أو ال
+
+217
+00:16:30,460 --> 00:16:33,460
+order وفي عندنا ال effectors اللي هي ال muscles or
+
+218
+00:16:33,460 --> 00:16:36,900
+gland اللي بتستجيب لهذه ال ..
+
+219
+00:16:40,300 --> 00:16:45,320
+الراسم التوضيحي للـ Reflexes هي عبارة عن Automatic
+
+220
+00:16:45,320 --> 00:16:50,900
+Subconscious Responses to the stimuli within or
+
+221
+00:16:50,900 --> 00:16:55,740
+outside the body في عندنا Sensory Afferent Neurons
+
+222
+00:16:55,740 --> 00:16:59,380
+هي Sensory Receptors وفي عندنا بتروح على
+
+223
+00:16:59,380 --> 00:17:03,830
+الـCentral Nervous Systems وSpinal Cord أوفالمصر
+
+224
+00:17:03,830 --> 00:17:07,390
+في عندنا ال motor inference اللي هي اللي خليني
+
+225
+00:17:07,390 --> 00:17:12,830
+أقول المواصلات ال .. الهابطة وفي عندنا ال muscle
+
+226
+00:17:12,830 --> 00:17:17,350
+orgland اللي هي بدها تعملي خليني أقول الحركة
+
+227
+00:17:17,350 --> 00:17:22,620
+تبعدني عن هذهالمخاطرة يعني المستقبلات على الجذب
+
+228
+00:17:22,620 --> 00:17:27,100
+تستقبل .. بتشعر بالخطر، بتبعتها عن طريق الـ
+
+229
+00:17:27,100 --> 00:17:29,880
+afferent neurons إلى ال central nervous system،
+
+230
+00:17:29,880 --> 00:17:33,580
+بتنزل عن طريق الafferent motor neuron على ال
+
+231
+00:17:33,580 --> 00:17:38,100
+muscles أو ال glands حتى تستجيبهنا في عندنا الـ
+
+232
+00:17:38,100 --> 00:17:42,120
+monosynaptic زي الـ knee jerk أو simplest of all
+
+233
+00:17:42,120 --> 00:17:46,140
+reflexes هنا مافيش inter neurons لأنها مباشرة
+
+234
+00:17:46,140 --> 00:17:52,160
+بتيجي على مركز ال reflex و بترجع للعضلة نفسها زي
+
+235
+00:17:52,160 --> 00:17:59,590
+البتلر أو knee jerk reflexمونو سيناتيك رفليكس أما
+
+236
+00:17:59,590 --> 00:18:03,250
+ال بولي سيناتيك رفليكس have more complex in neural
+
+237
+00:18:03,250 --> 00:18:07,690
+pathway بده number of synapses فيه inter neurons
+
+238
+00:18:07,690 --> 00:18:14,840
+within the reflex has more componentsأكثر تأخير
+
+239
+00:18:14,840 --> 00:18:20,280
+مستمرة بين المشاركة والإجابة. طبعا هنا الاختبار في
+
+240
+00:18:20,280 --> 00:18:23,140
+موقع الكلينيكال يمكن أن يكون استخدام الـ reflexes
+
+241
+00:18:23,140 --> 00:18:29,360
+لتجارب مجموعة مخصصة ونيرب مخصص مخصص أو جزء من جزء
+
+242
+00:18:29,360 --> 00:18:30,120
+من الجزء من الجزء من الجزء من الجزء من الجزء من
+
+243
+00:18:30,120 --> 00:18:31,240
+الجزء من الجزء من الجزء من الجزء من الجزء من الجزء
+
+244
+00:18:31,240 --> 00:18:32,400
+من الجزء من الجزء من الجزء من الجزء من الجزء من
+
+245
+00:18:32,400 --> 00:18:32,960
+الجزء من الجزء من الجزء من الجزء من الجزء من الجزء
+
+246
+00:18:32,960 --> 00:18:32,960
+من الجزء من الجزء من الجزء من الجزء من الجزء من
+
+247
+00:18:32,960 --> 00:18:34,440
+الجزء من الجزء من الجزء من الجزء من الجزء من الجزء
+
+248
+00:18:34,440 --> 00:18:39,040
+منdamage في nervous system or muscle طبعا احنا أول
+
+249
+00:18:39,040 --> 00:18:41,920
+حاجة بروح على دكتور الأعصاب تفحص ال reflexش بس
+
+250
+00:18:41,920 --> 00:18:47,580
+انها بتبين حالة ال central nervous system a reflex
+
+251
+00:18:47,580 --> 00:18:51,780
+response may be اما normal اما hypoactive او
+
+252
+00:18:51,780 --> 00:18:55,080
+hyperactive ال normal reflex هو الطبيعي اما
+
+253
+00:18:55,080 --> 00:18:57,720
+hypoactive معناه reflex ضييف hyperactive
+
+254
+00:18:57,720 --> 00:19:01,550
+exaggerated reflexيعني بيدرب على النيفة جروحه هو
+
+255
+00:19:01,550 --> 00:19:09,930
+الرجل خطأ في يعني مرفوع الطريقة عنيفة مثلافي ال
+
+256
+00:19:09,930 --> 00:19:13,130
+clinical application في عندنا cerebral injuries
+
+257
+00:19:13,130 --> 00:19:17,470
+and abnormalities ممكن يكون في عندنا على ال
+
+258
+00:19:17,470 --> 00:19:20,970
+concussion عبارة عن ال concussion ال brain
+
+259
+00:19:20,970 --> 00:19:25,070
+concussion يسمى الارتجاج في ال brain بيكون ال
+
+260
+00:19:25,070 --> 00:19:29,270
+brain jarred against ال cranium بيصير فيه و كأنه
+
+261
+00:19:29,270 --> 00:19:34,690
+انخض كده ال brain جواد زي في حالة حوادث الطرق اللي
+
+262
+00:19:34,690 --> 00:19:40,120
+اتكلمنا عنها في المحاضرة السابقةبيكون صار ضربة في
+
+263
+00:19:40,120 --> 00:19:44,680
+الدماغ داخل الكرانيوم انهزت او انخدت كده بيصير
+
+264
+00:19:44,680 --> 00:19:48,440
+فيها بتاعها loss of consciousness ممكن بيصير
+
+265
+00:19:48,440 --> 00:19:53,080
+temporarily loss of memory بيقل الذاكرة و بيصير
+
+266
+00:19:53,080 --> 00:19:57,960
+احيانا mental cloudings بيصير الشخص مش كتير مركز و
+
+267
+00:19:57,960 --> 00:20:02,680
+مدرك و بيصيب صداع شديد و طبعا بيصير recovery
+
+268
+00:20:02,680 --> 00:20:08,360
+احيانا complete او دائما بيكون usuallyأنا بصير
+
+269
+00:20:08,360 --> 00:20:13,960
+بروفاسكيلار اكسيدنس فهي من الأمراض اللي بتصيب ال
+
+270
+00:20:13,960 --> 00:20:18,880
+brain زي ال stroke بصير sudden interruption في ال
+
+271
+00:20:18,880 --> 00:20:22,120
+blood flow بتوقف ال blood بصير block نتيجة blood
+
+272
+00:20:22,120 --> 00:20:27,100
+block اقلط أو انسداد في أحد الشرايين و طبعا في بعض
+
+273
+00:20:27,100 --> 00:20:33,330
+ال brain ال tissue بصير فيها dyingأما الـ cerebral
+
+274
+00:20:33,330 --> 00:20:37,750
+palsy فهي حالة من الـ motor impairment في ال birth
+
+275
+00:20:37,750 --> 00:20:41,850
+بتكون ناجحة عن الـ blocked cerebral blood vessel
+
+276
+00:20:41,850 --> 00:20:46,530
+during development بتصير معها ال seizures اللي هي
+
+277
+00:20:46,530 --> 00:20:51,730
+التشنجاتوبيتبعها learning disabilities وخاصة هذي
+
+278
+00:20:51,730 --> 00:20:57,150
+بسبب الفرصة بيصيب الأطفال ال number ممكن pre or
+
+279
+00:20:57,150 --> 00:21:01,330
+pre or postnatal وبيقدي إلى او بنقول اي حادث
+
+280
+00:21:01,330 --> 00:21:05,650
+بتعرضله الطفل في ال brainعلى ال brand يصير عنده
+
+281
+00:21:05,650 --> 00:21:09,970
+brand دمج قبل سن سنتين فهو يعاد سيرفرال بلس زي
+
+282
+00:21:09,970 --> 00:21:13,670
+حالات ال car accidents زي الحالات الغرق قبل سن
+
+283
+00:21:13,670 --> 00:21:18,030
+سنتين هذا أيضا بيعاد لأن هذه فترة development of
+
+284
+00:21:18,030 --> 00:21:22,150
+ال brand لأن ال brand ماكنش مكتملنقوم بهذه احنا
+
+285
+00:21:22,150 --> 00:21:28,330
+بنكون أنهينا محاضراتنا لفي مساق ال anatomy وانا
+
+286
+00:21:28,330 --> 00:21:31,450
+بتمنى ان يكونوا وجودي معاكم ساعتكم في الفترة
+
+287
+00:21:31,450 --> 00:21:38,860
+السابقة في خلينا نقوليعني وضع بعض اللمسات أو
+
+288
+00:21:38,860 --> 00:21:42,220
+التركيز على بعض النقاط اللي لازم احنا نحفظها و
+
+289
+00:21:42,220 --> 00:21:45,920
+لازم احنا نعرفها في مجال ال Anatomy Online لأن
+
+290
+00:21:45,920 --> 00:21:49,760
+لمساق ال Anatomy ممثقة كتير مهمة للناس اللي بتدرس
+
+291
+00:21:49,760 --> 00:21:55,390
+ال healthلكل ال health professions لأن هو بتعامل
+
+292
+00:21:55,390 --> 00:21:59,130
+مع صحة الإنسان عشان يتعامل مع صحة الإنسان هذا لازم
+
+293
+00:21:59,130 --> 00:22:03,670
+يكون معرفة بتشريح أعضاء الإنسان وبهيك ان شاء الله
+
+294
+00:22:03,670 --> 00:22:07,070
+نلتقي معاكم في مساقات أخرى ويعطيكم العافية
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0.srt
new file mode 100644
index 0000000000000000000000000000000000000000..26a430a61f6c6a3bc39fd280482961cdc16728fc
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0.srt
@@ -0,0 +1,863 @@
+1
+00:00:04,930 --> 00:00:10,090
+باسم الله الرحمن الرحيم محاضرتنا اليوم الثانية في
+
+2
+00:00:10,090 --> 00:00:13,170
+موضوع
+
+3
+00:00:13,170 --> 00:00:16,510
+ال nervous system سنتكلم فيها عن ال brain. تبقى لنا
+
+4
+00:00:16,510 --> 00:00:20,530
+محاضرة بعدها وهي الأخيرة عن ال spinal cord. سنتعرف
+
+5
+00:00:20,530 --> 00:00:25,270
+على أجزاء ال brain و على ال
+
+6
+00:00:25,270 --> 0:00:30,870
+cranial nerves و كذلك على ال CSF الموجود في ال
+
+7
+00:00:30,870 --> 00:00:35,290
+brain. طبعا ال brain of the adult body تقريبا وزنه
+
+8
+00:00:35,290 --> 00:00:39,930
+واحد وخمسة وثلاثين يعني 1.35 أو
+
+9
+00:00:39,930 --> 00:00:44,590
+1.4 kilogram. طبعا حوالي ثلاثة pound
+
+10
+00:00:44,590 --> 00:00:51,540
+الذي طبعا حجمه حوالي ألف ومئتا centimeter مكعب.
+
+11
+00:00:51,540 --> 00:00:55,940
+brain size. طبعا، مقدار حجم ال brain لا يدل على حجم
+
+12
+00:00:55,940 --> 00:00:59,420
+الذكاء عند الشخص، وهذه معلومة مهمة جداً، أنه يعني
+
+13
+00:00:59,420 --> 00:01:03,180
+ليس كلما كبر الرأس كان الشخص ذكياً، أو كلما كبر
+
+14
+00:01:03,180 --> 00:01:06,820
+ال brain.  بل يعتمد الذكاء على عدد ال
+
+15
+00:01:06,820 --> 00:01:11,900
+activated synapses في ال brain. يعني ليس حجم ال
+
+16
+00:01:11,900 --> 00:01:14,140
+brain هو الذي يحدد مستوى الذكاء.
+
+17
+00:01:17,860 --> 00:01:22,180
+وظيفة ال brain. نحن نعرف أن الدماغ هو الذي
+
+18
+00:01:22,180 --> 00:01:27,240
+يُعدّ الجزء المسؤول عن تفسير ال sensations.  يعني إذا
+
+19
+00:01:27,240 --> 00:01:30,580
+أنا أرى... أرى قدامي كاميرا، أرى قدامي
+
+20
+00:01:30,580 --> 00:01:34,200
+كراسي، أرى قدامي laptop. الذي يُفسّر هذا الكلام
+
+21
+00:01:34,200 --> 00:01:37,670
+العين التي ترى، لكنها ترسل للدماغ، وهو الذي يقوم بـ
+
+22
+00:01:37,670 --> 00:01:42,470
+interpretation. يحدد ال perception، وهو الفهم و
+
+23
+00:01:42,470 --> 00:01:47,090
+الإدراك. يخزن ال memory. طبعاً، إذا أنا مثلاً أُعطي
+
+24
+00:01:47,090 --> 00:01:50,570
+هذه المحاضرة، فبالتأكيد أنا قرأتها، تُخزّن في ال
+
+25
+00:01:50,570 --> 00:01:52,810
+memory عندي المعلومات الموجودة فيها، التي أنا
+
+26
+00:01:52,810 --> 00:01:56,530
+سأشرحها، وهكذا. نحن نتذكر ماذا أكلنا بالأمس، و
+
+27
+00:01:56,530 --> 00:02:00,210
+أين ذهبنا بالأمس، قبل عشرة أيام، ماذا كنا نفعل، من جاء علينا
+
+28
+00:02:00,210 --> 00:02:03,810
+من... هذه ال memory storage. أما أيضاً ال reasoning
+
+29
+00:02:03,810 --> 00:02:08,860
+كيف نحن نقدر الأشياء، كيف نقرر أيضاً. هذا
+
+30
+00:02:08,860 --> 00:02:12,480
+الدماغ. كلما قلنا بهدف لأن عقله كبير، لماذا؟ لأنه
+
+31
+00:02:12,480 --> 00:02:16,640
+يقال عنه عقله كبير لأنه يُوزن الأشياء بشكل صحيح.
+
+32
+00:02:16,640 --> 00:02:20,680
+coordinate muscular movement. إذا قررت أن أمسك
+
+33
+00:02:20,680 --> 00:02:24,440
+الشغل، قررت أن أعمل، أشتغل على ال laptop، أو
+
+34
+00:02:24,440 --> 00:02:27,600
+أمسك، أو أكل، أو أشرب، فهذا المسؤول عنه هو ال
+
+35
+00:02:27,600 --> 00:02:32,740
+coordination، وهو ال brain.  وكذلك ينظم ال viscera
+
+36
+00:02:32,740 --> 00:02:37,960
+يعني عملية ال secretions، والهضم، والتنفس، وضربات
+
+37
+00:02:37,960 --> 00:02:43,000
+القلب، كلها ينظمها أيضاً ال brain. ويحدد شخصية
+
+38
+00:02:43,000 --> 00:02:51,240
+البني آدم. في عندنا four major regions في ال... ال
+
+39
+00:02:51,240 --> 00:02:56,460
+brain. نحن في ال forebrain، وال midbrain، وال hindbrain
+
+40
+00:02:56,460 --> 00:03:04,360
+وكذلك ال occipital part. فال forebrain أو ال
+
+41
+00:03:04,360 --> 00:03:07,290
+telencephalon، الذي هو ال
+
+42
+00:03:07,290 --> 00:03:10,870
+cerebrum، و ال diencephalon، الذي هو ال thalamus، وال
+
+43
+00:03:10,870 --> 00:03:15,870
+hypothalamus. و ال hypothalamus هما ال forebrain
+
+44
+00:03:15,870 --> 00:03:20,150
+اللذان موجودان في مقدمة الرأس. وفي ال mesencephalon
+
+45
+00:03:20,150 --> 00:03:23,350
+الذي هو ال midbrain، يتكلم من ال pons، و
+
+46
+00:03:23,350 --> 00:03:29,410
+ال colliculi. وفي ال rhombencephalon الذي هو ال hindbrain
+
+47
+00:03:29,410 --> 00:03:33,270
+الذي يتكون من ال pons، و ال cerebellum، وكما ال
+
+48
+00:03:33,270 --> 00:03:37,250
+medulla oblongata.
+
+49
+00:03:41,360 --> 00:03:44,200
+ال cerebrum divided. طبعاً، خلينا نتكلم لو
+
+50
+00:03:44,200 --> 00:03:47,360
+تكلمنا عن ال cerebrum لوحده، فهو نحن طول عمرنا
+
+51
+00:03:47,360 --> 00:03:51,800
+نعرف أن ال cerebrum يتكون من two hemispheres. في
+
+52
+00:03:51,800 --> 00:03:54,360
+عندنا right hemisphere، وفي عندنا left hemisphere.
+
+53
+00:03:54,360 --> 00:03:57,880
+الطبيعي، نحن نعرف أن ال right hemisphere مسؤولة
+
+54
+00:03:57,880 --> 00:04:02,080
+عن ال left part of the body، يعني ال left upper and
+
+55
+00:04:02,080 --> 00:04:06,320
+lower limb. و ال left hemisphere مسؤولة عن ال right
+
+56
+00:04:06,320 --> 00:04:11,380
+part of the body. Each hemisphere. في عندنا خمسة من
+
+57
+00:04:11,380 --> 00:04:15,380
+ال functional areas تُسمى ال lobes. ال outer surface
+
+58
+00:04:15,380 --> 00:04:19,740
+of an adult brain exhibit folds. في عنده زي انثناءات
+
+59
+00:04:19,740 --> 00:04:24,860
+تُسمى gyri أو جيرس، و shallow depressions تُسمى
+
+60
+00:04:24,860 --> 00:04:28,420
+sulci.  المنطقة التي جعلتها تشبه الجروف أو
+
+61
+00:04:28,710 --> 00:04:33,050
+المنخفضات. ال brain طبعاً، منه يخرج من ال
+
+62
+00:04:33,050 --> 00:04:37,270
+cerebrum يخرج منه عندنا twelve pairs of cranial
+
+63
+00:04:37,270 --> 00:04:46,910
+nerves. طبعاً هذه صورة توضيحية لـ، خلينا نقول، ال brain
+
+64
+00:04:48,190 --> 00:04:53,710
+كما نحن نرى، شكل ال gyri وشكل ال sulci، حتى
+
+65
+00:04:53,710 --> 00:04:57,770
+نحن نرى، لو نظرنا لحبة جوز، كيف نجد فيها
+
+66
+00:04:57,770 --> 00:05:04,450
+يعني مناطق عالية ومنخفضات، تعطيني هذا الشكل
+
+67
+00:05:04,450 --> 00:05:09,280
+بالضبط، شكل ال brain مثل حبة جوزة الهند، إذا
+
+68
+00:05:09,280 --> 00:05:13,300
+أنتم تعرفونها وترون ال sulci كيف شكلها،
+
+69
+00:05:13,300 --> 00:05:17,380
+و ال gyri كيف شكلهما. وفي عندنا ال front part، وفي
+
+70
+00:05:17,380 --> 00:05:22,040
+عندنا ال posterior part of the brain. وكما نحن
+
+71
+00:05:22,040 --> 00:05:26,440
+نرى، ال lobes of the cerebrum، ال
+
+72
+00:05:26,440 --> 00:05:30,060
+frontal، و ال parietal lobes. وكما في عندنا ال
+
+73
+00:05:30,060 --> 00:05:35,200
+temporal، و ال occipital lobe. وهذا بقية شكل ال hindbrain
+
+74
+00:05:35,200 --> 00:05:38,980
+مثل ال cerebellum، ال pons، و ال medulla oblongata
+
+75
+00:05:38,980 --> 00:05:44,620
+التي تنتهي، ثم تذهب مع ال spinal، تنتهي بعمل
+
+76
+00:05:44,620 --> 00:05:47,880
+امتداد لـ ال spinal cord، الذي يحدث بعده
+
+77
+00:05:47,880 --> 00:05:53,360
+decassation، ويحدث في القلب، في، خلينا نقول، يحدث
+
+78
+00:05:53,360 --> 00:05:57,000
+الجزء ال right مسؤول عن ال left part of the body، و
+
+79
+00:05:57,000 --> 00:06:01,070
+ال left مسؤول عن ال right part of the body. كما
+
+80
+00:06:01,070 --> 00:06:09,510
+نحن نرى هنا صورة مقطع من ال brain. كما
+
+81
+00:06:09,510 --> 00:06:15,770
+نحن نرى هنا عندنا ال cranial nerves، كلها سنتعرف
+
+82
+00:06:15,770 --> 00:06:16,330
+عليها.
+
+83
+00:06:19,650 --> 00:06:22,630
+ال lobes of the cerebral hemisphere. في عندنا ال
+
+84
+00:06:22,630 --> 00:06:26,410
+frontal، و ال parietal، و ال temporal، و ال occipital
+
+85
+00:06:26,410 --> 00:06:33,850
+وهذه صورة، هي جزء صغير هكذا ما بين ال frontal
+
+86
+00:06:33,850 --> 00:06:37,370
+و ال temporal lobe.
+
+87
+00:06:40,340 --> 00:06:43,180
+طبعاً، ال functional region of the cerebral cortex
+
+88
+00:06:43,180 --> 00:06:49,200
+هو عبارة عن ال cortex، وهو a thin layer of grey matter
+
+89
+00:06:49,200 --> 00:06:52,580
+that constitutes the outermost portion of the
+
+90
+00:06:52,580 --> 00:06:57,800
+cerebrum، أو تحتوي على حوالي 75% of all neurons in the
+
+91
+00:06:57,800 --> 00:07:01,050
+nervous system. التي موجودة تماماً في ال cerebrum
+
+92
+00:07:01,050 --> 00:07:06,410
+لأنه مسؤول عن الكثير من الوظائف، في 75% من ال neurons
+
+93
+00:07:06,410 --> 00:07:09,270
+الموجودة في ال nervous system موجودة في ال cerebral
+
+94
+00:07:09,270 --> 00:07:15,190
+cortex. وهذا رسم توضيحي يعطينا كيف وأين المناطق
+
+95
+00:07:15,190 --> 00:07:19,410
+على حسب وجودها في ال cerebrum، تُغذي أجزاءً من أعضاء
+
+96
+00:07:19,410 --> 00:07:24,070
+الجسم. نذهب إلى ال diencephalon، الذي هو عبارة عن
+
+97
+00:07:24,070 --> 00:07:26,610
+ال thalamus و ال hypothalamus.  Between cerebral
+
+98
+00:07:26,610 --> 00:07:29,990
+hemispheres and above the brainstem. يعني هي بين ال
+
+99
+00:07:29,990 --> 00:07:34,990
+cerebral hemispheres، وفوق ال brainstem. وفي
+
+100
+00:07:34,990 --> 00:07:41,730
+لها ثلاث تجاويف، surrounded the third ventricles.
+
+101
+00:07:43,440 --> 00:07:48,760
+ال thalamus هو ال gateway for sensory impulses
+
+102
+00:07:48,760 --> 00:07:52,700
+heading to the cerebral cortex. يعني قبل ما تصل ال
+
+103
+00:07:52,700 --> 00:07:56,440
+impulse، تأتي عن طريق ال thalamus، وتذهب إلى ال
+
+104
+00:07:56,440 --> 0:08:01,780
+cortex. يستقبل all sensory input except smell. كل ال
+
+105
+00:08:01,780 --> 00:08:05,280
+sensory input يأتي عن طريق ال thalamus، وينتقل إلى ال
+
+106
+00:08:05,280 --> 00:08:08,690
+cortex، من أجل ال interpretation. طبعاً، ال channel
+
+107
+00:08:08,690 --> 00:08:11,410
+impulses to appropriate part of the cerebral
+
+108
+00:08:11,410 --> 00:08:16,330
+cortex for interpretation. طبعاً، يساعد على عملية
+
+109
+00:08:16,330 --> 00:08:19,890
+ترجمة الأشياء التي نراها. أما ال hypothalamus
+
+110
+00:08:19,890 --> 00:08:25,950
+فهو maintains homeostasis. يساعد على الحالة التوازن
+
+111
+00:08:25,950 --> 00:08:30,070
+الموجودة في ال viscera، عن طريق regulation
+
+112
+00:08:30,070 --> 00:08:34,670
+لل visceral activity.  يُنشئ link ما بين ال nervous
+
+113
+00:08:34,670 --> 00:08:38,210
+system وبين ال endocrine system. نحن قلنا أن أي
+
+114
+00:08:38,210 --> 00:08:42,170
+stimulus نحن نستقبله، الذي يتحكم في الجسم بعدها
+
+115
+00:08:42,170 --> 00:08:45,630
+إما ال nervous system، مع ال nervous system، مع ال
+
+116
+00:08:45,630 --> 00:08:48,350
+endocrine. لكن الأسرع الذي يتصرف على طول، هو ال
+
+117
+00:08:48,350 --> 00:08:51,670
+nervous system. وبعده يبدأ إفراز الهرمونات من أجل
+
+118
+00:08:51,670 --> 00:08:55,700
+أن تساعدنا في عملية التوازن بين البيئة الداخلية
+
+119
+00:08:55,700 --> 00:09:03,240
+والبيئة الخارجية للجسم. فمن خلال عملية الوصول
+
+120
+00:09:03,240 --> 00:09:06,320
+هذه، أو ال link، التي تحدث بين ال nervous و ال endocrine
+
+121
+00:09:06,320 --> 00:09:10,450
+تكون في ال hypothalamus.  هناك جزء في ال diencephalon
+
+122
+00:09:10,450 --> 00:09:14,270
+يُسمى limbic system.  وهو يتكون من ماذا؟
+
+123
+00:09:14,270 --> 00:09:17,910
+portions من ال frontal lobe، و portions من ال
+
+124
+00:09:17,910 --> 00:09:21,050
+temporal lobe. وفي عندنا ال hypothalamus، و
+
+125
+00:09:21,050 --> 00:09:23,930
+ال thalamus، و ال basal nuclei، و other deep
+
+126
+00:09:23,930 --> 00:09:27,770
+nuclei. وماذا؟ ووظيفة ال limbic system تساعد على
+
+127
+00:09:27,770 --> 00:09:31,370
+التحكم في ال emotions، وتعطيك الشعور، يعني أنا
+
+128
+00:09:31,370 --> 00:09:37,290
+حزين، أنا سعيد، أنا مُكتئب، أنا متفائل، أنا... هذا
+
+129
+00:09:37,290 --> 00:09:41,090
+كله يُفسّر أو يُتحكّم فيه
+
+130
+00:09:41,090 --> 00:09:44,790
+ال limbic system. وهو يقوم بتفسير ال
+
+131
+00:09:44,790 --> 00:09:49,190
+sensory impulses. ال brainstem طبعاً، يتكون من
+
+132
+00:09:49,190 --> 00:09:51,530
+ثلاثة أجزاء، ال midbrain، و ال pons، و
+
+133
+00:09:51,530 --> 00:09:55,330
+ال medulla oblongata. و ال midbrain موجود بين
+
+134
+00:09:55,330 --> 00:10:00,110
+ال diencephalon و ال pons، ويحتوي على bundles of
+
+135
+00:10:00,110 --> 00:10:02,750
+fibers التي تربط الجزء السفلي من ال brainstem و
+
+136
+00:10:02,750 --> 00:10:09,100
+ال spinal cord. قلنا ال pons الذي... ال medulla oblongata
+
+137
+00:10:09,100 --> 00:10:14,560
+هي عبارة عن، بعد أن تنتهي، تذهب إلى ال spinal cord، فهي
+
+138
+00:10:14,560 --> 00:10:17,800
+lower part of the brainstem and spinal cord with
+
+139
+00:10:17,800 --> 00:10:23,720
+higher part of the brain. هي عملية الوصل ما بين ال
+
+140
+00:10:23,720 --> 00:10:28,540
+spinal cord و ال brain.
+
+141
+00:10:29,370 --> 00:10:33,170
+ال pons rounded bulge كما رأيناها قبل قليل
+
+142
+00:10:33,170 --> 00:10:37,230
+في الرسم، on the underside of the brainstem، between
+
+143
+00:10:37,230 --> 00:10:41,750
+ال medulla oblongata و ال midbrain. help regulate rate
+
+144
+00:10:41,750 --> 00:10:44,950
+and depth of breathing. تتحكم ال pons تتحكم في
+
+145
+00:10:44,950 --> 00:10:50,730
+ال breathing، و release nervous impulses to and from
+
+146
+00:10:50,730 --> 00:10:54,530
+ال medulla oblongata and cerebellum. تحاول أن تقوم بترجمة
+
+147
+00:10:54,850 --> 00:11:02,690
+أو تفسير ال sensory impulses التي تأتي من ال pons أو
+
+148
+00:11:02,690 --> 00:11:06,370
+ال cerebrum. أما ال medulla oblongata فهي enlarged
+
+149
+00:11:06,370 --> 00:11:11,290
+continuation of the spinal cord. هي عبارة عن ال medulla
+
+150
+00:11:11,290 --> 00:11:14,370
+oblongata، هي الوصلة ما بين ال brain وبين ال spinal
+
+151
+00:11:14,370 --> 00:11:19,770
+cord. conducts ascending and descending impulses.
+
+152
+00:11:19,770 --> 00:11:22,770
+يعني في impulse صاعدة للدماغ، وفي impulse نازلة من
+
+153
+00:11:22,770 --> 00:11:25,930
+الدماغ، between the brain and spinal cord. يعني هي
+
+154
+00:11:25,930 --> 00:11:29,510
+عملية حلقة الوصل ما بين ال brain وبين ال spinal
+
+155
+00:11:29,510 --> 00:11:33,760
+cord. عن طريق elevator تساعد و elevator nasal
+
+156
+00:11:33,760 --> 00:11:39,120
+Contains Cardiac و Vasomotor و Respiratory Control
+
+157
+00:11:39,120 --> 00:11:43,840
+Centers. لأن هذه في حالات الشنق هي التي تؤدي إلى
+
+158
+00:11:43,840 --> 00:11:50,340
+الوفاة، لأنها تقطع الاتصال عن كل الأشياء الحيوية
+
+159
+00:11:50,340 --> 00:11:55,180
+أو المراكز الحيوية في الجسم، مثل القلب والأوعية
+
+160
+00:11:55,180 --> 00:11:59,910
+الدموية والتنفس. فهي عملية الشنق تحدث عن طريقها. من
+
+161
+00:11:59,910 --> 00:12:04,230
+خلال ال medulla oblongata عن ال brain من هذه المنطقة
+
+162
+00:12:04,230 --> 00:12:09,290
+فتحدث الوفاة فوراً. Contains various non-verbal
+
+163
+00:12:09,290 --> 00:12:13,070
+reflex control مثل ال coughing، و ال sneezing، و ال
+
+164
+00:12:13,070 --> 00:12:18,850
+swallowing، و ال vomiting. يعني السعال، والعطس، و
+
+165
+00:12:18,850 --> 00:12:25,870
+البلع، والتقيؤ وغيره. أما ال cerebellum فهو
+
+166
+00:12:25,870 --> 00:12:28,970
+inferior to the occipital lobe. تحت ال occipital
+
+167
+00:12:28,970 --> 00:12:32,170
+lobe of the cerebrum، posterior to the pons and
+
+168
+00:12:32,170 --> 00:12:38,690
+medulla oblongata. كما نحن نراه بهذا الشكل،
+
+169
+00:12:38,690 --> 00:12:42,510
+هذا ال cerebellum له أيضاً two hemispheres مثل
+
+170
+00:12:42,510 --> 00:12:48,010
+ال cerebrum. وله vermis connects ال hemispheres.
+
+171
+00:12:48,010 --> 00:12:53,570
+في وصلة ما بين ال hemispheres.  Cerebral cortex تتكون من
+
+172
+00:12:53,570 --> 00:13:00,300
+a grey matter كذلك، و a layer of white
+
+173
+00:13:00,300 --> 00:13:04,360
+matter. و cerebellar peduncles nerve fibers tracks
+
+174
+00:13:04,360 --> 00:13:09,820
+و dentate (dentate) nucleus. large، هي ال largest
+
+175
+00:13:09,820 --> 00:13:13,520
+nucleus في ال cerebellum. هو طبيعياً يقوم بعمل integration
+
+176
+00:13:13,520 --> 00:13:17,200
+between sensory information، التي لها علاقة في
+
+177
+00:13:17,200 --> 00:13:20,660
+position of the body parts. الذي يحافظ على توازن
+
+178
+00:13:20,920 --> 00:13:25,680
+الجسم. هو ال coordination skeletal muscle activity.
+
+179
+00:13:25,680 --> 00:13:29,460
+ويحافظ على البشر. طبعاً الشخص الذي يكون لديه
+
+180
+00:13:29,460 --> 00:13:32,980
+مشكلة في ال cerebellum يعاني من شيء يُسمى ataxia.
+
+181
+00:13:32,980 --> 00:13:37,260
+ال ataxia هي lack of coordination. لأن الجسم دائماً
+
+182
+00:13:37,260 --> 00:13:44,040
+يترجح. وهذا شكل ال cerebellum كما نراه
+
+183
+00:13:44,040 --> 00:13:47,180
+posterior to the p
+
+223
+00:16:47,530 --> 00:16:49,950
+الـ space اللى تحت الـ arachnoid وفى عندنا الـ
+
+224
+00:16:49,950 --> 00:16:53,530
+diameterاللي هي delicate mater adhered tightly to
+
+225
+00:16:53,530 --> 00:16:56,370
+the surface of the spinal cord نفس الـMeninges هذه
+
+226
+00:16:56,370 --> 00:17:00,330
+اللي في الـ brain في الـ ventricles اللي هي الفجوات
+
+227
+00:17:00,330 --> 00:17:06,010
+اللي موجودة بتعمل connection عبارة هي عن تجاويف
+
+228
+00:17:06,010 --> 00:17:09,650
+مترابطة within the cerebral hemispheres and brain
+
+229
+00:17:09,650 --> 00:17:14,670
+stem وتمتد continuously with the central canal of
+
+230
+00:17:14,670 --> 00:17:18,870
+the spinal cord وفيها مليئة بالـcerebrospinal
+
+231
+00:17:18,870 --> 00:17:26,000
+fluid اللي هو CSF وهي الـ largest in the cerebellum
+
+232
+00:17:26,000 --> 00:17:31,040
+في عندنا lateral ventricles في عندنا right and left
+
+233
+00:17:31,040 --> 00:17:34,100
+في عندنا الثالثة اللي هي third ventricle بين
+
+234
+00:17:34,100 --> 00:17:37,820
+الـ thalami و between right and left thalami وفي
+
+235
+00:17:37,820 --> 00:17:40,700
+عندنا الرابعة الـ fourth ventricle posterior
+
+236
+00:17:40,700 --> 00:17:46,410
+والـ cerebral aqueduct connects the third and fourth ventricles
+
+237
+00:17:46,410 --> 00:17:50,350
+cerebrospinal fluid هو عبارة عن fluid secreted by
+
+238
+00:17:50,350 --> 00:17:55,690
+a choroid plexus، circulates in the ventricles,
+
+239
+00:17:55,770 --> 00:17:58,570
+central canal of the spinal cord and subarachnoid
+
+240
+00:17:58,570 --> 00:18:03,040
+space وفي الـ CSF دائما، إيش بتعطينا؟الـ nutrition
+
+241
+00:18:03,040 --> 00:18:06,340
+و الـ protection كمان هو عبارة عن clear liquid
+
+242
+00:18:06,340 --> 00:18:12,200
+يعني سائل شفاف بيحيط الـ spinal cord والـ brain
+
+243
+00:18:12,200 --> 00:18:16,640
+كمان بيساعد على الـ stability للـ ions فيه والـ
+
+244
+00:18:16,640 --> 00:18:21,090
+concentration في الـ central nervous systemوالـ ...
+
+245
+00:18:21,090 --> 00:18:25,670
+في عندنا foramina or linked between ventricles
+
+246
+00:18:25,670 --> 00:18:29,970
+وفي interventricular foramina, ventricles, foramina linked
+
+247
+00:18:29,970 --> 00:18:35,730
+between third and lateral ventricles وهذه طبعا الـ
+
+248
+00:18:35,730 --> 00:18:39,930
+style الأخيرة معانا في هذه المحاضرة نسمع كتير عن
+
+249
+00:18:39,930 --> 00:18:43,350
+lumbar puncture الـ lumbar puncture بتاخد خليني
+
+250
+00:18:43,350 --> 00:18:50,390
+أقول عينة أو كمية من الـ ..الـ CSF بتتم فحصها خاصة
+
+251
+00:18:50,390 --> 00:18:57,090
+في حالات الـ meningitis وكمان بيصير في أحيانًا
+
+252
+00:18:57,090 --> 00:19:01,010
+لإعطاء الـ epidural anesthesia فبيدخلوا الإبرة من
+
+253
+00:19:01,010 --> 00:19:06,710
+هذه المنطقة يعطيكم العافية وإن شاء الله بتبقى
+
+254
+00:19:06,710 --> 00:19:09,570
+عندنا المحاضرة الأخيرة عن الـ spinal cord إن شاء
+
+255
+00:19:09,570 --> 00:19:10,270
+الله رب العالمين
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0_postprocess.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..fa09a9742aa5a8aada08cc5cc9d4cf15ab5b06c4
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0_postprocess.srt
@@ -0,0 +1,1020 @@
+1
+00:00:04,930 --> 00:00:10,090
+باسم الله الرحمن الرحيم محاضرتنا اليوم تانية في
+
+2
+00:00:10,090 --> 00:00:13,170
+موضوع
+
+3
+00:00:13,170 --> 00:00:16,510
+ال nervous system هنتكلم فيها عن ال brain تبقى لنا
+
+4
+00:00:16,510 --> 00:00:20,530
+محاضرة بعدها و هي الأخيرة عن ال spinal cord هنتعرف
+
+5
+00:00:20,530 --> 00:00:25,270
+على أجزاء من خلالها على أجزاء ال brain و على ال
+
+6
+00:00:25,270 --> 00:00:30,870
+cranial nerve و كذلك على ال CSF الموجود في ال
+
+7
+00:00:30,870 --> 00:00:35,290
+brainطبعا ال brain of the adult body تقريبا وزنه
+
+8
+00:00:35,290 --> 00:00:39,930
+واحد وخمس و تلاتين يعني واحد point خمس و تلاتين او
+
+9
+00:00:39,930 --> 00:00:44,590
+واحد point اربع kilogram طبعا حوالي تلاتة pound
+
+10
+00:00:44,590 --> 00:00:51,540
+اللي طبعا حجمه حوالي الف و متين centimeter مكعبال
+
+11
+00:00:51,540 --> 00:00:55,940
+brain size طبعا قداش حجم ال brain ما بيدلل على حجم
+
+12
+00:00:55,940 --> 00:00:59,420
+الذكاء عند الشخص و هذه معلومة كتير مهمة أنه يعني
+
+13
+00:00:59,420 --> 00:01:03,180
+مش كل ما كبر الرأس يعني الشخص كان ذكي أو كل ما كبر
+
+14
+00:01:03,180 --> 00:01:06,820
+ال brain لأ هو بيعتمد الذكاء على ال number of
+
+15
+00:01:06,820 --> 00:01:11,900
+activated synapses في ال brain يعني مش ال size ال
+
+16
+00:01:11,900 --> 00:01:14,140
+brain هو اللي بيحدد ال intellectual
+
+17
+00:01:17,860 --> 00:01:22,180
+وظيفة ال brain احنا بنعرف ان الدماغ هو يعني خلانا
+
+18
+00:01:22,180 --> 00:01:27,240
+نقول الجزء المسؤول عن تفسير ال sensation يعني اذا
+
+19
+00:01:27,240 --> 00:01:30,580
+أنا شايفة .. شايفة قدامي كاميرا، شايفة قدامي
+
+20
+00:01:30,580 --> 00:01:34,200
+كراسي، شايفة قدامي laptop اللي بيفسر هذا الكلام
+
+21
+00:01:34,200 --> 00:01:37,670
+العيني اللي بتشوف لكن بترسل لدماغ هو اللي بيعملالـ
+
+22
+00:01:37,670 --> 00:01:42,470
+interpretation بيحدد ال perception اللي هو الفهم و
+
+23
+00:01:42,470 --> 00:01:47,090
+الإدراك بيخزن ال memory طبعا انا اذا مثلا أجيب
+
+24
+00:01:47,090 --> 00:01:50,570
+اعطي هذه المحاضرة فعالأكيد أنا قرأتها تخزن في ال
+
+25
+00:01:50,570 --> 00:01:52,810
+memory عندي المعلومات اللي موجودة فيها اللي أنا
+
+26
+00:01:52,810 --> 00:01:56,530
+جاية أشرحها و هكذا احنا بنتذكر إيش أكلنا مبارح و
+
+27
+00:01:56,530 --> 00:02:00,210
+أين روحنا مبارح قبل عشر أيام ما كنا مين إجي علينا
+
+28
+00:02:00,210 --> 00:02:03,810
+مين .. هذه ال memory storage أما كمان ال reasoning
+
+29
+00:02:03,810 --> 00:02:08,860
+كيف أنه احنا بنقدر الأشياءالـ كيف بنقرر كمان هذا
+
+30
+00:02:08,860 --> 00:02:12,480
+الدماغ كل ما بنقول بهدف لان عقله كبير ليش؟ لأنه
+
+31
+00:02:12,480 --> 00:02:16,640
+بيقولوا عنه عقله كبير لأنه هو بيوزن الأشياء صحيح
+
+32
+00:02:16,640 --> 00:02:20,680
+coordinate muscular movement إذا قررت أني أنا أمسك
+
+33
+00:02:20,680 --> 00:02:24,440
+الشغل قررت أني أعمل فيها أشتغل على ال laptop أو
+
+34
+00:02:24,440 --> 00:02:27,600
+أمسك أو أكل أو أشرب فهذا المسئول على ال
+
+35
+00:02:27,600 --> 00:02:32,740
+coordination هوال brain و كمان بينظم ال viscera
+
+36
+00:02:32,740 --> 00:02:37,960
+يعني عملية ال secretions و الحدم و التنفس و لدقات
+
+37
+00:02:37,960 --> 00:02:43,000
+القلب كلها بنظمها كمان ال brain و بيحدد شخصية
+
+38
+00:02:43,000 --> 00:02:51,240
+البني آدمفي عندنا four major regions في ال .. ال
+
+39
+00:02:51,240 --> 00:02:56,460
+brain احنا في ال four و ال mid و ال hind ال brain
+
+40
+00:02:56,460 --> 00:03:04,360
+و كمان ال occipital part فال four brain او ال bra
+
+41
+00:03:04,360 --> 00:03:07,290
+and cephalonفي ال teleencephalon اللي هو ال
+
+42
+00:03:07,290 --> 00:03:10,870
+cerebrum و ال encephalon اللي هو ال thalamus و ال
+
+43
+00:03:10,870 --> 00:03:15,870
+hypothalamus و ال hypothalamus هم ال four brain
+
+44
+00:03:15,870 --> 00:03:20,150
+اللي موجودين في مقدمة الرقص و في ال mesencephalon
+
+45
+00:03:20,150 --> 00:03:23,350
+اللي هو ال midbrain اللي تتكلم من ال venacles و
+
+46
+00:03:23,350 --> 00:03:29,410
+الcolocaeوفي ال رومبو انسفلانس اللى هو الهنتبران
+
+47
+00:03:29,410 --> 00:03:33,270
+اللى بتكون من ال bones و ال cerebellum و كمان اللى
+
+48
+00:03:33,270 --> 00:03:37,250
+مضلق من جاتا في الخل
+
+49
+00:03:41,360 --> 00:03:44,200
+الـ cerebrum divided طبعا احنا خليني اتكلم لو
+
+50
+00:03:44,200 --> 00:03:47,360
+اتكلمنا عن ال cerebrum لحاله فهو احنا طول عمرنا
+
+51
+00:03:47,360 --> 00:03:51,800
+بنعرف ان ال cerebrum بتكون من two hemispheres في
+
+52
+00:03:51,800 --> 00:03:54,360
+عندنا right hemisphere و في عندنا left hemisphere
+
+53
+00:03:54,360 --> 00:03:57,880
+الطبيعي احنا بنعرف ان ال right hemisphere مسئولة
+
+54
+00:03:57,880 --> 00:04:02,080
+عن ال left part of the body يعني ال left upper and
+
+55
+00:04:02,080 --> 00:04:06,320
+lower limb و ال left hemisphere مسئولة عن ال right
+
+56
+00:04:06,320 --> 00:04:11,380
+part of the bodyEach hemisphere فى عندنا خمسة من
+
+57
+00:04:11,380 --> 00:04:15,380
+ال functional area بتسمى ال loops ال outer surface
+
+58
+00:04:15,380 --> 00:04:19,740
+of an adult brain exhibit faults فى عنده زى اثنيات
+
+59
+00:04:19,740 --> 00:04:24,860
+بتسمى gyrus أو جيرس and shallow depressions بتسمى
+
+60
+00:04:24,860 --> 00:04:28,420
+السلقاي المنطقة اللى خلينا عاملة زى الجروف أو
+
+61
+00:04:28,710 --> 00:04:33,050
+المنخفضة المنخفضة ال brain طبعا فيه بيطلع من ال
+
+62
+00:04:33,050 --> 00:04:37,270
+cerebrum بيطلع فيه عندنا twelve pair of cranial
+
+63
+00:04:37,270 --> 00:04:46,910
+nerves طبعا هذه صورة توضحية لخلنا نقول ل brain
+
+64
+00:04:48,190 --> 00:04:53,710
+زي ما احنا شايفين شكل الجيرس وشكل الصلصاي عشانكي
+
+65
+00:04:53,710 --> 00:04:57,770
+احنا بنطلع لو طلعنا على حبة جوز كيف بنلاقي فيها
+
+66
+00:04:57,770 --> 00:05:04,450
+يعني مناطق عالية ومناطق واطية بتعطيني الشكل هذا
+
+67
+00:05:04,450 --> 00:05:09,280
+بالظبط شكل ال brain زي حبة الجوزالعين الجمل إذا
+
+68
+00:05:09,280 --> 00:05:13,300
+أنتوا بتعرفوها وشايفين أنتوا الصلقاي كيف شكلها
+
+69
+00:05:13,300 --> 00:05:17,380
+والجيراس كيف شكلها وفي عندنا ال front part وفي
+
+70
+00:05:17,380 --> 00:05:22,040
+عندنا ال posterior part of the brain وزي ما إحنا
+
+71
+00:05:22,040 --> 00:05:26,440
+شايفين ال loops of the cerebellar ال cerebrum ال
+
+72
+00:05:26,440 --> 00:05:30,060
+frontal و ال parietal هادي وكمان في عندنا ال
+
+73
+00:05:30,060 --> 00:05:35,200
+temporalوالـ occipital lobe وهذا بقيت شكل اللبنان
+
+74
+00:05:35,200 --> 00:05:38,980
+زي الـ cerebellum الـ bones والمضلة الابلنجاتا
+
+75
+00:05:38,980 --> 00:05:44,620
+اللي بتنتهي بعدها بتروح مع ال spinal بتنتهي بتعمل
+
+76
+00:05:44,620 --> 00:05:47,880
+امتداد ل ال spinal cord اللي بيصير بعدها في
+
+77
+00:05:47,880 --> 00:05:53,360
+decassation وبيصير في القلب في فلن نقول بيصير
+
+78
+00:05:53,360 --> 00:05:57,000
+الجزء ال right مسئول عن ال left part of the body و
+
+79
+00:05:57,000 --> 00:06:01,070
+ال left مسئول عن ال right part of the bodyزي ما
+
+80
+00:06:01,070 --> 00:06:09,510
+احنا شايفين هنا شكل صورة مقطع من الإبراهيم زي ما
+
+81
+00:06:09,510 --> 00:06:15,770
+احنا شايفين هنا عندنا ال cranial nerves كلها هتعرف
+
+82
+00:06:15,770 --> 00:06:16,330
+عليها
+
+83
+00:06:19,650 --> 00:06:22,630
+الـ loops of the cerebral hemisphere في عندنا ال
+
+84
+00:06:22,630 --> 00:06:26,410
+frontal و الbrital و ال temporal و ال occipital
+
+85
+00:06:26,410 --> 00:06:33,850
+وهي صولة هيها جزء صغير كده ما بينهم بين ال frontal
+
+86
+00:06:33,850 --> 00:06:37,370
+و ال temporal loop
+
+87
+00:06:40,340 --> 00:06:43,180
+طبعا ال functional region of the cerebral cortex
+
+88
+00:06:43,180 --> 00:06:49,200
+هو عبارة ال cortex هو a thin layer of grey matter
+
+89
+00:06:49,200 --> 00:06:52,580
+that constitute the outermost portion of the
+
+90
+00:06:52,580 --> 00:06:57,800
+cerebrum أو بتحوالي فيها 75% of all neurons in the
+
+91
+00:06:57,800 --> 00:07:01,050
+nervous systemالذين موجودين تماما في الـ cerebrum
+
+92
+00:07:01,050 --> 00:07:06,410
+لأنه مسؤول عن كثير من الوضع في 75% من ال neurones
+
+93
+00:07:06,410 --> 00:07:09,270
+الموجودة في nervous system موجودة في cerebral
+
+94
+00:07:09,270 --> 00:07:15,190
+cortex وهذا رسم توضيحي يعطينا كيف و أين المناطق
+
+95
+00:07:15,190 --> 00:07:19,410
+على حسب وجودها في الcerebrum بتغضي أش من أعضاء
+
+96
+00:07:19,410 --> 00:07:24,070
+الجسمنروح للدين Encephalon اللي هو عبارة عن
+
+97
+00:07:24,070 --> 00:07:26,610
+الـthalamus و الـ hypothalamus between cerebral
+
+98
+00:07:26,610 --> 00:07:29,990
+hemisphere and above the brainstem يعني هي بين ال
+
+99
+00:07:29,990 --> 00:07:34,990
+cerebral hemispheres و أعلى من ال brainstem و في
+
+100
+00:07:34,990 --> 00:07:41,730
+إلها تلتة cavities surrounded the third ventricles
+
+101
+00:07:43,440 --> 00:07:48,760
+الـ thalamus هو ال gateway for sensory impulses
+
+102
+00:07:48,760 --> 00:07:52,700
+heading to the cerebral cortex يعني قبل ما توصل ال
+
+103
+00:07:52,700 --> 00:07:56,440
+impulse بتيجي عن طريق ال thalamus و بتروح على ال
+
+104
+00:07:56,440 --> 00:08:01,780
+cortex بستقبل all sensory input except smell كل ال
+
+105
+00:08:01,780 --> 00:08:05,280
+sensory input بيجي عن طريق ال thalamus و بنتقل لال
+
+106
+00:08:05,280 --> 00:08:08,690
+cortex عشان ال interpretationطبعا ال channel
+
+107
+00:08:08,690 --> 00:08:11,410
+impulses to appropriate part of the cerebral
+
+108
+00:08:11,410 --> 00:08:16,330
+cortex for interpretation طبعا بساعد على عملية
+
+109
+00:08:16,330 --> 00:08:19,890
+ترجمة الأشياء اللي احنا بنشوفها أما الhypothalamus
+
+110
+00:08:19,890 --> 00:08:25,950
+فهو maintain hemostasis بساعد على الحالة التوازن
+
+111
+00:08:25,950 --> 00:08:30,070
+اللي موجودةفي الـ viscera عن طريق regulation
+
+112
+00:08:30,070 --> 00:08:34,670
+للvisceral activity بيعمل link ما بين ال nervous
+
+113
+00:08:34,670 --> 00:08:38,210
+system وبين ال endocrine system احنا حكينا انه اي
+
+114
+00:08:38,210 --> 00:08:42,170
+stimulus احنا بنستقبلها اللي بيتحكم في الجسم بعدها
+
+115
+00:08:42,170 --> 00:08:45,630
+اما ال nervous system مع ال nervous system مع ال
+
+116
+00:08:45,630 --> 00:08:48,350
+endocrine لكن الأسرع اللي بتصرف على طول عندنا ال
+
+117
+00:08:48,350 --> 00:08:51,670
+nervous system و بعده بيبدأ افراز الهرمونات عشان
+
+118
+00:08:51,670 --> 00:08:55,700
+تساعدنافي العملية التوازن بين البيئة الداخلية
+
+119
+00:08:55,700 --> 00:09:03,240
+والبيئة الخارجية تبع الجسم فمن في العملية الوصول
+
+120
+00:09:03,240 --> 00:09:06,320
+هذه أو ال link بتصير بين ال nervous وال endocrine
+
+121
+00:09:06,320 --> 00:09:10,450
+بتكون في ال hypothalamusهي حاجة في الدين
+
+122
+00:09:10,450 --> 00:09:14,270
+encephalon called limbic system هو بتكون من ايش
+
+123
+00:09:14,270 --> 00:09:17,910
+portions من ال frontal loop و portions من ال
+
+124
+00:09:17,910 --> 00:09:21,050
+temporal loop وفي عندنا ال hypothalamus و
+
+125
+00:09:21,050 --> 00:09:23,930
+الthalamus و ال basal ال nuclei و other deep
+
+126
+00:09:23,930 --> 00:09:27,770
+nucleiوإيش؟ وبيفت ال limbic system بيساعد على
+
+127
+00:09:27,770 --> 00:09:31,370
+التحكم في ال emotions وبيعطيك الفيرن، يعني انا
+
+128
+00:09:31,370 --> 00:09:37,290
+حزين، انا سعيد، انا مقتقب، انا متفائل، انا .. هذا
+
+129
+00:09:37,290 --> 00:09:41,090
+كله بيصيرله interpretation أو بيصيرله control في
+
+130
+00:09:41,090 --> 00:09:44,790
+ال limbic system و هو بيعمل interpretation لل
+
+131
+00:09:44,790 --> 00:09:49,190
+sensory impulsesالـ Brain Stem طبعا فيه بتكون من
+
+132
+00:09:49,190 --> 00:09:51,530
+الـ three parts، الـ midbrain و الـ bones و
+
+133
+00:09:51,530 --> 00:09:55,330
+البطالة ابلونجاتا و ال midbrain موجود بين
+
+134
+00:09:55,330 --> 00:10:00,110
+الـdensyphalin و الـ bone و بيحتوي على bundles of
+
+135
+00:10:00,110 --> 00:10:02,750
+fibers which joins the lower part of brain stem و
+
+136
+00:10:02,750 --> 00:10:09,100
+ال spinal cord قلنا البون اللي ..المضالة Eblogata
+
+137
+00:10:09,100 --> 00:10:14,560
+هي عبارة بعد ما بنتهي بتروح لل spinal cord فهي
+
+138
+00:10:14,560 --> 00:10:17,800
+lower part of the brain stem and spinal cord with
+
+139
+00:10:17,800 --> 00:10:23,720
+higher part of the brain هي عملية الوصل ما بين ال
+
+140
+00:10:23,720 --> 00:10:28,540
+spinal cord و ال brain
+
+141
+00:10:29,370 --> 00:10:33,170
+الـ bones rounded bulge زي ما احنا شوفلها قبل شويه
+
+142
+00:10:33,170 --> 00:10:37,230
+بالرسم on the underside of the brain stem between
+
+143
+00:10:37,230 --> 00:10:41,750
+المضلة أبلونجاتا و ال midbrain help regulate rate
+
+144
+00:10:41,750 --> 00:10:44,950
+and depth of breathing بتتحكم ال bones بتتحكم في
+
+145
+00:10:44,950 --> 00:10:50,730
+ال breathing و release nervous impulse to and from
+
+146
+00:10:50,730 --> 00:10:54,530
+المضلة أبلونجاتا and cerebellum بتحاول تعمل ترجمة
+
+147
+00:10:54,850 --> 00:11:02,690
+أو تفسير لل sensory impulse اللى جاية من مجلة أو
+
+148
+00:11:02,690 --> 00:11:06,370
+السرب اللىأما المدلة ابلنجاتا فهي enlarged
+
+149
+00:11:06,370 --> 00:11:11,290
+continuation of the spinal cord هي عبارة عن المدلة
+
+150
+00:11:11,290 --> 00:11:14,370
+ابلنجاتا هي الوصلة ما بين ال brain و بين ال spinal
+
+151
+00:11:14,370 --> 00:11:19,770
+cord conducts ascending and descending impulses
+
+152
+00:11:19,770 --> 00:11:22,770
+يعني في impulse سارع للدمغ و في impulse نازلة من
+
+153
+00:11:22,770 --> 00:11:25,930
+الدماغ between the brain and spinal cord يعني هي
+
+154
+00:11:25,930 --> 00:11:29,510
+عملية حلقة الوصل ما بين ال brain و بين ال spinal
+
+155
+00:11:29,510 --> 00:11:33,760
+cord عن طريق elevator ساعد و elevatorNasal
+
+156
+00:11:33,760 --> 00:11:39,120
+Contains Cardiac و Vasomotor و Respiratory Control
+
+157
+00:11:39,120 --> 00:11:43,840
+Centers عشان هذه في حالات الشنق هي اللي بتأدي الى
+
+158
+00:11:43,840 --> 00:11:50,340
+الوفاة لإنها بتقطع الاتصال عن كل الأشياء الحيوية
+
+159
+00:11:50,340 --> 00:11:55,180
+أو المراكز الحيوية في الجسم زي القلب والأوائل
+
+160
+00:11:55,180 --> 00:11:59,910
+الدموية والتنفس فهي عملية الشنق بتصير عن طريقهامن
+
+161
+00:11:59,910 --> 00:12:04,230
+تفسر المدلة ابن جاتى عن ال brain من هذه المنطقة
+
+162
+00:12:04,230 --> 00:12:09,290
+فبتدى الوفع فورا Contains various non-verbal
+
+163
+00:12:09,290 --> 00:12:13,070
+reflex control زى ال coughing و ال sneezing و ال
+
+164
+00:12:13,070 --> 00:12:18,850
+swallowing و ال vomiting يعنى السؤال و العطس و
+
+165
+00:12:18,850 --> 00:12:25,870
+البلاء و التقيق و غيره أما ال cerebellumفهو
+
+166
+00:12:25,870 --> 00:12:28,970
+inferior to the occipital lobe تحت الـ occipital
+
+167
+00:12:28,970 --> 00:12:32,170
+lobe of the cerebrum posterior to the bones and
+
+168
+00:12:32,170 --> 00:12:38,690
+medulla oblongata زي ما احنا شايفينه بهذا الشكل،
+
+169
+00:12:38,690 --> 00:12:42,510
+هاي الـ cerebellum بقالوا برضه two hemispheres زي
+
+170
+00:12:42,510 --> 00:12:48,010
+الcerebellum وقالوا vermins connect ال hemisphere
+
+171
+00:12:48,010 --> 00:12:53,570
+في وصلة ما بين ال hemisphere cerebral cortex بتكون
+
+172
+00:12:53,570 --> 00:13:00,300
+من a gray matterكمان و Airport فيتي للـ White
+
+173
+00:13:00,300 --> 00:13:04,360
+Matter وCerebellar peduncles nerve fibers tracks
+
+174
+00:13:04,360 --> 00:13:09,820
+وDentate دونتويد نيوكلياس large هي ال largest
+
+175
+00:13:09,820 --> 00:13:13,520
+nucleus في الcerebellum هو طبيعي بيعمل integration
+
+176
+00:13:13,520 --> 00:13:17,200
+between sensory information اللي هي لعلاقة في
+
+177
+00:13:17,200 --> 00:13:20,660
+position of the body part اللي بيحافظ على التوازن
+
+178
+00:13:20,920 --> 00:13:25,680
+الجسم هو ال coordination skeletal muscle activity
+
+179
+00:13:25,680 --> 00:13:29,460
+وبيحافظ على البشر طبعا الشخص اللي بيكون فيه عنده
+
+180
+00:13:29,460 --> 00:13:32,980
+مشكلة في ال cerebellum بيعاني من حاجة اسمها ataxia
+
+181
+00:13:32,980 --> 00:13:37,260
+ال ataxia هي lack of coordination لأن الجسم دائما
+
+182
+00:13:37,260 --> 00:13:44,040
+بيترنح وهذا شكل ال cerebellum زي ما احنا شايفينه
+
+183
+00:13:44,040 --> 00:13:47,180
+posterior to the bone
+
+184
+00:13:49,830 --> 00:13:55,790
+و هذا خلينا شكل توضيحي لكل أجزاء ال brain، فيكوا
+
+185
+00:13:55,790 --> 00:14:00,570
+أنه تقرأوه ببرحتكوا، هنا ال cerebellum و ال
+
+186
+00:14:00,570 --> 00:14:06,950
+thalamus و ال hypothalamus و ال bones و ال medulla
+
+187
+00:14:06,950 --> 00:14:10,790
+oblongata و ال cerebral hemisphere و كل واحدة مع
+
+188
+00:14:10,790 --> 00:14:15,450
+ال function هذه بصراحة ال slide بكل المحاضرة اللي
+
+189
+00:14:15,450 --> 00:14:19,430
+احنا بتكلم عن ال function of different parts of
+
+190
+00:14:19,430 --> 00:14:23,330
+brainأما ال cranial nerves فقولنا زي ما في عندنا
+
+191
+00:14:23,330 --> 00:14:25,670
+spinal nerve في عندنا cranial nerve because ال
+
+192
+00:14:25,670 --> 00:14:29,930
+upper part of the body ال head و ال neck و ال .. و
+
+193
+00:14:29,930 --> 00:14:33,630
+ال jaw و ال swallowing و hair و طبعا في عندنا
+
+194
+00:14:33,630 --> 00:14:37,970
+dwell pairs of cranial nerve بتبدأ في أول cranial
+
+195
+00:14:37,970 --> 00:14:43,950
+nerve هو الفكتوري و الشمو ال .. ال .. ال optic و
+
+196
+00:14:43,950 --> 00:14:48,850
+ال oculomotor و ال procular و ال trigeminal و ال
+
+197
+00:14:48,850 --> 00:14:52,910
+abducens و ال facial و العصب السابع اللي دايما
+
+198
+00:14:52,910 --> 00:14:57,670
+بيصير فيه مشاكل أو بيصير فيه بيسموها لفة الوجه و
+
+199
+00:14:57,670 --> 00:15:01,590
+glossopharyngeal و ال accessory فيه عند العصب
+
+200
+00:15:01,590 --> 00:15:05,810
+العاشر هو ال Vegas اللي احنا شايفينهوالـ
+
+201
+00:15:05,810 --> 00:15:10,730
+Hypocholestial و ال vestibular و ال cochlear و ال
+
+202
+00:15:10,730 --> 00:15:17,670
+.. هيك بيكونوا كلهم تقريبا طبعا أنا ال meninges of
+
+203
+00:15:17,670 --> 00:15:21,870
+the brain ففي عندنا three layers of meninges اللي
+
+204
+00:15:21,870 --> 00:15:25,530
+بتسمع الحاجة اسمها meninges هيش وظيفة ال meninges
+
+205
+00:15:25,530 --> 00:15:28,630
+و قلتها بنسميها الصحة طب هذه ال meninges هيش
+
+206
+00:15:28,630 --> 00:15:31,670
+وظيفتها و وظيفتها تلاتة layer من ال meninges
+
+207
+00:15:31,670 --> 00:15:38,430
+بتساعد على حماية ال brainبتعمل زي غشاء بيحمي
+
+208
+00:15:38,430 --> 00:15:42,850
+البران وغشاء هذا موجود في ال CSF بيحمي البران من
+
+209
+00:15:42,850 --> 00:15:47,010
+الصدمة طبعا تلاتة layers ال durable matter ال
+
+210
+00:15:47,010 --> 00:15:50,690
+outer أو ال tough أو بيسموه الأم الجافية ال
+
+211
+00:15:50,690 --> 00:15:55,030
+arachnoid matter هو thin و whoop like أما ال
+
+212
+00:15:55,030 --> 00:15:59,050
+biomatter فهي ال inner peritone بيسموهبالأم الحنون
+
+213
+00:15:59,050 --> 00:16:04,030
+لإن هو ملاصق لخلايا
+
+214
+00:16:04,030 --> 00:16:08,150
+ال brain وهذه الخلايا أثناء العمليات الجراحية
+
+215
+00:16:08,150 --> 00:16:13,890
+المنجيز اللي بتتم فتحها عشان يدخلوا لبراين وهنا زي
+
+216
+00:16:13,890 --> 00:16:17,690
+ما احنا شايفين ال virus والسلكال of the brain
+
+217
+00:16:17,690 --> 00:16:21,590
+وشايفين كيف في عندنا blood vessels
+
+218
+00:16:23,810 --> 00:16:26,910
+طبعا فى لإن ال spinal meninges برضه فى عندنا
+
+219
+00:16:26,910 --> 00:16:29,810
+الديورة ال top فى اللى بنسميه ال mother strong ال
+
+220
+00:16:29,810 --> 00:16:34,090
+arachnoid هذا الخارجى اللى صعب أنه ينفتح وفى عندنا
+
+221
+00:16:34,090 --> 00:16:40,710
+ال arachnoid فى spider looking عامل زى كأنه spider
+
+222
+00:16:40,710 --> 00:16:47,530
+عن كبوتى اكرد blood vessels وفى عندنا subarachnoid
+
+223
+00:16:47,530 --> 00:16:49,950
+ال space اللى تحت ال arachnoid وفى عندنا ال
+
+224
+00:16:49,950 --> 00:16:53,530
+diameterاللي هي delicate mother adhered tightly to
+
+225
+00:16:53,530 --> 00:16:56,370
+the surface of the spinal cord نفس الـMeninges هذه
+
+226
+00:16:56,370 --> 00:17:00,330
+اللي في الإبراهيم في عين الفنتركلز اللي هي الفجوات
+
+227
+00:17:00,330 --> 00:17:06,010
+اللي موجودة بتعمل connection عبارة هي عن تجاويف
+
+228
+00:17:06,010 --> 00:17:09,650
+مترابطة within the cerebral hemisphere and brain
+
+229
+00:17:09,650 --> 00:17:14,670
+stem وتمتد continuously with the central canal of
+
+230
+00:17:14,670 --> 00:17:18,870
+the spinal cord وفيها مليئة بالcerebral spinal
+
+231
+00:17:18,870 --> 00:17:26,000
+fluid اللي هو CSFهي ال largest in the cerebellum
+
+232
+00:17:26,000 --> 00:17:31,040
+في عندنا lateral ventricle في عندنا right and left
+
+233
+00:17:31,040 --> 00:17:34,100
+في عندنا التالتة اللي هي third ventricle في الدين
+
+234
+00:17:34,100 --> 00:17:37,820
+السفلان و between right and left thalamus وفي
+
+235
+00:17:37,820 --> 00:17:40,700
+عندنا الرابعة ال fourth ventricle post bones
+
+236
+00:17:40,700 --> 00:17:46,410
+وcerebral aqueducts third and fourth ventriclesالـ
+
+237
+00:17:46,410 --> 00:17:50,350
+cerebrospinal fluid هو عبارة عن fluid secreted by
+
+238
+00:17:50,350 --> 00:17:55,690
+a choroid plexus، circulates in the ventricle,
+
+239
+00:17:55,770 --> 00:17:58,570
+central canal of the spinal cord and subarachnoid
+
+240
+00:17:58,570 --> 00:18:03,040
+space وفي الـ CSF دائما، إيش بتعطينا؟الـ nutrition
+
+241
+00:18:03,040 --> 00:18:06,340
+و ال protection كمان هو عبارة عن clear liquids
+
+242
+00:18:06,340 --> 00:18:12,200
+يعني سائل شفاف بيحيط ال spinal cord and ال brain
+
+243
+00:18:12,200 --> 00:18:16,640
+كمان بيساعد على ال stability لل ions فيه و ال
+
+244
+00:18:16,640 --> 00:18:21,090
+concentration في ال central nervous systemوال ..
+
+245
+00:18:21,090 --> 00:18:25,670
+في عندنا formula like او linked between ventricles
+
+246
+00:18:25,670 --> 00:18:29,970
+وفي interventriculars, ventricles, formula linked
+
+247
+00:18:29,970 --> 00:18:35,730
+between third and lateral ventricles وهذه طبعا ال
+
+248
+00:18:35,730 --> 00:18:39,930
+style الأخيرة معانا في هذه المحاضرة نسمع كتير عن
+
+249
+00:18:39,930 --> 00:18:43,350
+lumber puncture ال lumber puncture بتاخد خليني
+
+250
+00:18:43,350 --> 00:18:50,390
+أقول غزعة أو كمية من ال ..الـ CSF بتتم فحصها خاصة
+
+251
+00:18:50,390 --> 00:18:57,090
+في حالات الـ meningitis وكمان بيصير في أحيان
+
+252
+00:18:57,090 --> 00:19:01,010
+المناقشة ال epidural من الانستيزيا فبيدخلولها من
+
+253
+00:19:01,010 --> 00:19:06,710
+هذه المنطقة يعطيكم العافية و ان شاء الله بتبقى
+
+254
+00:19:06,710 --> 00:19:09,570
+عندنا المحاضرة الأخيرة عن ال spinal cord ان شاء
+
+255
+00:19:09,570 --> 00:19:10,270
+الله رب العالمين
+
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0_raw.json b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..6a104b111e604aefdf863732276574e0a43600df
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0_raw.json
@@ -0,0 +1 @@
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خاصة", "probability": 0.9811197916666666}, {"start": 1130.39, "end": 1130.57, "word": " في", "probability": 0.91748046875}, {"start": 1130.57, "end": 1131.59, "word": " حالات", "probability": 0.96484375}, {"start": 1131.59, "end": 1132.73, "word": " الـ", "probability": 0.5992431640625}, {"start": 1132.73, "end": 1134.23, "word": " meningitis", "probability": 0.91259765625}, {"start": 1134.23, "end": 1134.95, "word": " وكمان", "probability": 0.87060546875}, {"start": 1134.95, "end": 1135.95, "word": " بيصير", "probability": 0.909912109375}, {"start": 1135.95, "end": 1136.23, "word": " في", "probability": 0.85400390625}, {"start": 1136.23, "end": 1137.09, "word": " أحيان", "probability": 0.923095703125}, {"start": 1137.09, "end": 1137.59, "word": " المناقشة", "probability": 0.693701171875}, {"start": 1137.59, "end": 1137.63, "word": " ال", "probability": 0.83642578125}, {"start": 1137.63, "end": 1138.27, "word": " epidural", "probability": 0.794921875}, {"start": 1138.27, "end": 1138.59, "word": " من", "probability": 0.95654296875}, {"start": 1138.59, "end": 1139.47, "word": " الانستيزيا", "probability": 0.7779134114583334}, {"start": 1139.47, "end": 1140.51, "word": " فبيدخلولها", "probability": 0.9457310267857143}, {"start": 1140.51, "end": 1141.01, "word": " من", "probability": 0.9921875}, {"start": 1141.01, "end": 1141.51, "word": " هذه", "probability": 0.92041015625}, {"start": 1141.51, "end": 1143.39, "word": " المنطقة", "probability": 0.9736328125}, {"start": 1143.39, "end": 1144.23, "word": " يعطيكم", "probability": 0.7193603515625}, {"start": 1144.23, "end": 1145.03, "word": " العافية", "probability": 0.9715169270833334}, {"start": 1145.03, "end": 1145.77, "word": " و", "probability": 0.9765625}, {"start": 1145.77, "end": 1145.91, "word": " ان", "probability": 0.489501953125}, {"start": 1145.91, "end": 1146.11, "word": " شاء", "probability": 0.994873046875}, {"start": 1146.11, "end": 1146.23, "word": " الله", "probability": 0.9501953125}, {"start": 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\ No newline at end of file
diff --git a/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0_raw.srt b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..fa09a9742aa5a8aada08cc5cc9d4cf15ab5b06c4
--- /dev/null
+++ b/PL9fwy3NUQKwYRCKRj3m3Un55qTWreF8t2/sfRik6iDM-0_raw.srt
@@ -0,0 +1,1020 @@
+1
+00:00:04,930 --> 00:00:10,090
+باسم الله الرحمن الرحيم محاضرتنا اليوم تانية في
+
+2
+00:00:10,090 --> 00:00:13,170
+موضوع
+
+3
+00:00:13,170 --> 00:00:16,510
+ال nervous system هنتكلم فيها عن ال brain تبقى لنا
+
+4
+00:00:16,510 --> 00:00:20,530
+محاضرة بعدها و هي الأخيرة عن ال spinal cord هنتعرف
+
+5
+00:00:20,530 --> 00:00:25,270
+على أجزاء من خلالها على أجزاء ال brain و على ال
+
+6
+00:00:25,270 --> 00:00:30,870
+cranial nerve و كذلك على ال CSF الموجود في ال
+
+7
+00:00:30,870 --> 00:00:35,290
+brainطبعا ال brain of the adult body تقريبا وزنه
+
+8
+00:00:35,290 --> 00:00:39,930
+واحد وخمس و تلاتين يعني واحد point خمس و تلاتين او
+
+9
+00:00:39,930 --> 00:00:44,590
+واحد point اربع kilogram طبعا حوالي تلاتة pound
+
+10
+00:00:44,590 --> 00:00:51,540
+اللي طبعا حجمه حوالي الف و متين centimeter مكعبال
+
+11
+00:00:51,540 --> 00:00:55,940
+brain size طبعا قداش حجم ال brain ما بيدلل على حجم
+
+12
+00:00:55,940 --> 00:00:59,420
+الذكاء عند الشخص و هذه معلومة كتير مهمة أنه يعني
+
+13
+00:00:59,420 --> 00:01:03,180
+مش كل ما كبر الرأس يعني الشخص كان ذكي أو كل ما كبر
+
+14
+00:01:03,180 --> 00:01:06,820
+ال brain لأ هو بيعتمد الذكاء على ال number of
+
+15
+00:01:06,820 --> 00:01:11,900
+activated synapses في ال brain يعني مش ال size ال
+
+16
+00:01:11,900 --> 00:01:14,140
+brain هو اللي بيحدد ال intellectual
+
+17
+00:01:17,860 --> 00:01:22,180
+وظيفة ال brain احنا بنعرف ان الدماغ هو يعني خلانا
+
+18
+00:01:22,180 --> 00:01:27,240
+نقول الجزء المسؤول عن تفسير ال sensation يعني اذا
+
+19
+00:01:27,240 --> 00:01:30,580
+أنا شايفة .. شايفة قدامي كاميرا، شايفة قدامي
+
+20
+00:01:30,580 --> 00:01:34,200
+كراسي، شايفة قدامي laptop اللي بيفسر هذا الكلام
+
+21
+00:01:34,200 --> 00:01:37,670
+العيني اللي بتشوف لكن بترسل لدماغ هو اللي بيعملالـ
+
+22
+00:01:37,670 --> 00:01:42,470
+interpretation بيحدد ال perception اللي هو الفهم و
+
+23
+00:01:42,470 --> 00:01:47,090
+الإدراك بيخزن ال memory طبعا انا اذا مثلا أجيب
+
+24
+00:01:47,090 --> 00:01:50,570
+اعطي هذه المحاضرة فعالأكيد أنا قرأتها تخزن في ال
+
+25
+00:01:50,570 --> 00:01:52,810
+memory عندي المعلومات اللي موجودة فيها اللي أنا
+
+26
+00:01:52,810 --> 00:01:56,530
+جاية أشرحها و هكذا احنا بنتذكر إيش أكلنا مبارح و
+
+27
+00:01:56,530 --> 00:02:00,210
+أين روحنا مبارح قبل عشر أيام ما كنا مين إجي علينا
+
+28
+00:02:00,210 --> 00:02:03,810
+مين .. هذه ال memory storage أما كمان ال reasoning
+
+29
+00:02:03,810 --> 00:02:08,860
+كيف أنه احنا بنقدر الأشياءالـ كيف بنقرر كمان هذا
+
+30
+00:02:08,860 --> 00:02:12,480
+الدماغ كل ما بنقول بهدف لان عقله كبير ليش؟ لأنه
+
+31
+00:02:12,480 --> 00:02:16,640
+بيقولوا عنه عقله كبير لأنه هو بيوزن الأشياء صحيح
+
+32
+00:02:16,640 --> 00:02:20,680
+coordinate muscular movement إذا قررت أني أنا أمسك
+
+33
+00:02:20,680 --> 00:02:24,440
+الشغل قررت أني أعمل فيها أشتغل على ال laptop أو
+
+34
+00:02:24,440 --> 00:02:27,600
+أمسك أو أكل أو أشرب فهذا المسئول على ال
+
+35
+00:02:27,600 --> 00:02:32,740
+coordination هوال brain و كمان بينظم ال viscera
+
+36
+00:02:32,740 --> 00:02:37,960
+يعني عملية ال secretions و الحدم و التنفس و لدقات
+
+37
+00:02:37,960 --> 00:02:43,000
+القلب كلها بنظمها كمان ال brain و بيحدد شخصية
+
+38
+00:02:43,000 --> 00:02:51,240
+البني آدمفي عندنا four major regions في ال .. ال
+
+39
+00:02:51,240 --> 00:02:56,460
+brain احنا في ال four و ال mid و ال hind ال brain
+
+40
+00:02:56,460 --> 00:03:04,360
+و كمان ال occipital part فال four brain او ال bra
+
+41
+00:03:04,360 --> 00:03:07,290
+and cephalonفي ال teleencephalon اللي هو ال
+
+42
+00:03:07,290 --> 00:03:10,870
+cerebrum و ال encephalon اللي هو ال thalamus و ال
+
+43
+00:03:10,870 --> 00:03:15,870
+hypothalamus و ال hypothalamus هم ال four brain
+
+44
+00:03:15,870 --> 00:03:20,150
+اللي موجودين في مقدمة الرقص و في ال mesencephalon
+
+45
+00:03:20,150 --> 00:03:23,350
+اللي هو ال midbrain اللي تتكلم من ال venacles و
+
+46
+00:03:23,350 --> 00:03:29,410
+الcolocaeوفي ال رومبو انسفلانس اللى هو الهنتبران
+
+47
+00:03:29,410 --> 00:03:33,270
+اللى بتكون من ال bones و ال cerebellum و كمان اللى
+
+48
+00:03:33,270 --> 00:03:37,250
+مضلق من جاتا في الخل
+
+49
+00:03:41,360 --> 00:03:44,200
+الـ cerebrum divided طبعا احنا خليني اتكلم لو
+
+50
+00:03:44,200 --> 00:03:47,360
+اتكلمنا عن ال cerebrum لحاله فهو احنا طول عمرنا
+
+51
+00:03:47,360 --> 00:03:51,800
+بنعرف ان ال cerebrum بتكون من two hemispheres في
+
+52
+00:03:51,800 --> 00:03:54,360
+عندنا right hemisphere و في عندنا left hemisphere
+
+53
+00:03:54,360 --> 00:03:57,880
+الطبيعي احنا بنعرف ان ال right hemisphere مسئولة
+
+54
+00:03:57,880 --> 00:04:02,080
+عن ال left part of the body يعني ال left upper and
+
+55
+00:04:02,080 --> 00:04:06,320
+lower limb و ال left hemisphere مسئولة عن ال right
+
+56
+00:04:06,320 --> 00:04:11,380
+part of the bodyEach hemisphere فى عندنا خمسة من
+
+57
+00:04:11,380 --> 00:04:15,380
+ال functional area بتسمى ال loops ال outer surface
+
+58
+00:04:15,380 --> 00:04:19,740
+of an adult brain exhibit faults فى عنده زى اثنيات
+
+59
+00:04:19,740 --> 00:04:24,860
+بتسمى gyrus أو جيرس and shallow depressions بتسمى
+
+60
+00:04:24,860 --> 00:04:28,420
+السلقاي المنطقة اللى خلينا عاملة زى الجروف أو
+
+61
+00:04:28,710 --> 00:04:33,050
+المنخفضة المنخفضة ال brain طبعا فيه بيطلع من ال
+
+62
+00:04:33,050 --> 00:04:37,270
+cerebrum بيطلع فيه عندنا twelve pair of cranial
+
+63
+00:04:37,270 --> 00:04:46,910
+nerves طبعا هذه صورة توضحية لخلنا نقول ل brain
+
+64
+00:04:48,190 --> 00:04:53,710
+زي ما احنا شايفين شكل الجيرس وشكل الصلصاي عشانكي
+
+65
+00:04:53,710 --> 00:04:57,770
+احنا بنطلع لو طلعنا على حبة جوز كيف بنلاقي فيها
+
+66
+00:04:57,770 --> 00:05:04,450
+يعني مناطق عالية ومناطق واطية بتعطيني الشكل هذا
+
+67
+00:05:04,450 --> 00:05:09,280
+بالظبط شكل ال brain زي حبة الجوزالعين الجمل إذا
+
+68
+00:05:09,280 --> 00:05:13,300
+أنتوا بتعرفوها وشايفين أنتوا الصلقاي كيف شكلها
+
+69
+00:05:13,300 --> 00:05:17,380
+والجيراس كيف شكلها وفي عندنا ال front part وفي
+
+70
+00:05:17,380 --> 00:05:22,040
+عندنا ال posterior part of the brain وزي ما إحنا
+
+71
+00:05:22,040 --> 00:05:26,440
+شايفين ال loops of the cerebellar ال cerebrum ال
+
+72
+00:05:26,440 --> 00:05:30,060
+frontal و ال parietal هادي وكمان في عندنا ال
+
+73
+00:05:30,060 --> 00:05:35,200
+temporalوالـ occipital lobe وهذا بقيت شكل اللبنان
+
+74
+00:05:35,200 --> 00:05:38,980
+زي الـ cerebellum الـ bones والمضلة الابلنجاتا
+
+75
+00:05:38,980 --> 00:05:44,620
+اللي بتنتهي بعدها بتروح مع ال spinal بتنتهي بتعمل
+
+76
+00:05:44,620 --> 00:05:47,880
+امتداد ل ال spinal cord اللي بيصير بعدها في
+
+77
+00:05:47,880 --> 00:05:53,360
+decassation وبيصير في القلب في فلن نقول بيصير
+
+78
+00:05:53,360 --> 00:05:57,000
+الجزء ال right مسئول عن ال left part of the body و
+
+79
+00:05:57,000 --> 00:06:01,070
+ال left مسئول عن ال right part of the bodyزي ما
+
+80
+00:06:01,070 --> 00:06:09,510
+احنا شايفين هنا شكل صورة مقطع من الإبراهيم زي ما
+
+81
+00:06:09,510 --> 00:06:15,770
+احنا شايفين هنا عندنا ال cranial nerves كلها هتعرف
+
+82
+00:06:15,770 --> 00:06:16,330
+عليها
+
+83
+00:06:19,650 --> 00:06:22,630
+الـ loops of the cerebral hemisphere في عندنا ال
+
+84
+00:06:22,630 --> 00:06:26,410
+frontal و الbrital و ال temporal و ال occipital
+
+85
+00:06:26,410 --> 00:06:33,850
+وهي صولة هيها جزء صغير كده ما بينهم بين ال frontal
+
+86
+00:06:33,850 --> 00:06:37,370
+و ال temporal loop
+
+87
+00:06:40,340 --> 00:06:43,180
+طبعا ال functional region of the cerebral cortex
+
+88
+00:06:43,180 --> 00:06:49,200
+هو عبارة ال cortex هو a thin layer of grey matter
+
+89
+00:06:49,200 --> 00:06:52,580
+that constitute the outermost portion of the
+
+90
+00:06:52,580 --> 00:06:57,800
+cerebrum أو بتحوالي فيها 75% of all neurons in the
+
+91
+00:06:57,800 --> 00:07:01,050
+nervous systemالذين موجودين تماما في الـ cerebrum
+
+92
+00:07:01,050 --> 00:07:06,410
+لأنه مسؤول عن كثير من الوضع في 75% من ال neurones
+
+93
+00:07:06,410 --> 00:07:09,270
+الموجودة في nervous system موجودة في cerebral
+
+94
+00:07:09,270 --> 00:07:15,190
+cortex وهذا رسم توضيحي يعطينا كيف و أين المناطق
+
+95
+00:07:15,190 --> 00:07:19,410
+على حسب وجودها في الcerebrum بتغضي أش من أعضاء
+
+96
+00:07:19,410 --> 00:07:24,070
+الجسمنروح للدين Encephalon اللي هو عبارة عن
+
+97
+00:07:24,070 --> 00:07:26,610
+الـthalamus و الـ hypothalamus between cerebral
+
+98
+00:07:26,610 --> 00:07:29,990
+hemisphere and above the brainstem يعني هي بين ال
+
+99
+00:07:29,990 --> 00:07:34,990
+cerebral hemispheres و أعلى من ال brainstem و في
+
+100
+00:07:34,990 --> 00:07:41,730
+إلها تلتة cavities surrounded the third ventricles
+
+101
+00:07:43,440 --> 00:07:48,760
+الـ thalamus هو ال gateway for sensory impulses
+
+102
+00:07:48,760 --> 00:07:52,700
+heading to the cerebral cortex يعني قبل ما توصل ال
+
+103
+00:07:52,700 --> 00:07:56,440
+impulse بتيجي عن طريق ال thalamus و بتروح على ال
+
+104
+00:07:56,440 --> 00:08:01,780
+cortex بستقبل all sensory input except smell كل ال
+
+105
+00:08:01,780 --> 00:08:05,280
+sensory input بيجي عن طريق ال thalamus و بنتقل لال
+
+106
+00:08:05,280 --> 00:08:08,690
+cortex عشان ال interpretationطبعا ال channel
+
+107
+00:08:08,690 --> 00:08:11,410
+impulses to appropriate part of the cerebral
+
+108
+00:08:11,410 --> 00:08:16,330
+cortex for interpretation طبعا بساعد على عملية
+
+109
+00:08:16,330 --> 00:08:19,890
+ترجمة الأشياء اللي احنا بنشوفها أما الhypothalamus
+
+110
+00:08:19,890 --> 00:08:25,950
+فهو maintain hemostasis بساعد على الحالة التوازن
+
+111
+00:08:25,950 --> 00:08:30,070
+اللي موجودةفي الـ viscera عن طريق regulation
+
+112
+00:08:30,070 --> 00:08:34,670
+للvisceral activity بيعمل link ما بين ال nervous
+
+113
+00:08:34,670 --> 00:08:38,210
+system وبين ال endocrine system احنا حكينا انه اي
+
+114
+00:08:38,210 --> 00:08:42,170
+stimulus احنا بنستقبلها اللي بيتحكم في الجسم بعدها
+
+115
+00:08:42,170 --> 00:08:45,630
+اما ال nervous system مع ال nervous system مع ال
+
+116
+00:08:45,630 --> 00:08:48,350
+endocrine لكن الأسرع اللي بتصرف على طول عندنا ال
+
+117
+00:08:48,350 --> 00:08:51,670
+nervous system و بعده بيبدأ افراز الهرمونات عشان
+
+118
+00:08:51,670 --> 00:08:55,700
+تساعدنافي العملية التوازن بين البيئة الداخلية
+
+119
+00:08:55,700 --> 00:09:03,240
+والبيئة الخارجية تبع الجسم فمن في العملية الوصول
+
+120
+00:09:03,240 --> 00:09:06,320
+هذه أو ال link بتصير بين ال nervous وال endocrine
+
+121
+00:09:06,320 --> 00:09:10,450
+بتكون في ال hypothalamusهي حاجة في الدين
+
+122
+00:09:10,450 --> 00:09:14,270
+encephalon called limbic system هو بتكون من ايش
+
+123
+00:09:14,270 --> 00:09:17,910
+portions من ال frontal loop و portions من ال
+
+124
+00:09:17,910 --> 00:09:21,050
+temporal loop وفي عندنا ال hypothalamus و
+
+125
+00:09:21,050 --> 00:09:23,930
+الthalamus و ال basal ال nuclei و other deep
+
+126
+00:09:23,930 --> 00:09:27,770
+nucleiوإيش؟ وبيفت ال limbic system بيساعد على
+
+127
+00:09:27,770 --> 00:09:31,370
+التحكم في ال emotions وبيعطيك الفيرن، يعني انا
+
+128
+00:09:31,370 --> 00:09:37,290
+حزين، انا سعيد، انا مقتقب، انا متفائل، انا .. هذا
+
+129
+00:09:37,290 --> 00:09:41,090
+كله بيصيرله interpretation أو بيصيرله control في
+
+130
+00:09:41,090 --> 00:09:44,790
+ال limbic system و هو بيعمل interpretation لل
+
+131
+00:09:44,790 --> 00:09:49,190
+sensory impulsesالـ Brain Stem طبعا فيه بتكون من
+
+132
+00:09:49,190 --> 00:09:51,530
+الـ three parts، الـ midbrain و الـ bones و
+
+133
+00:09:51,530 --> 00:09:55,330
+البطالة ابلونجاتا و ال midbrain موجود بين
+
+134
+00:09:55,330 --> 00:10:00,110
+الـdensyphalin و الـ bone و بيحتوي على bundles of
+
+135
+00:10:00,110 --> 00:10:02,750
+fibers which joins the lower part of brain stem و
+
+136
+00:10:02,750 --> 00:10:09,100
+ال spinal cord قلنا البون اللي ..المضالة Eblogata
+
+137
+00:10:09,100 --> 00:10:14,560
+هي عبارة بعد ما بنتهي بتروح لل spinal cord فهي
+
+138
+00:10:14,560 --> 00:10:17,800
+lower part of the brain stem and spinal cord with
+
+139
+00:10:17,800 --> 00:10:23,720
+higher part of the brain هي عملية الوصل ما بين ال
+
+140
+00:10:23,720 --> 00:10:28,540
+spinal cord و ال brain
+
+141
+00:10:29,370 --> 00:10:33,170
+الـ bones rounded bulge زي ما احنا شوفلها قبل شويه
+
+142
+00:10:33,170 --> 00:10:37,230
+بالرسم on the underside of the brain stem between
+
+143
+00:10:37,230 --> 00:10:41,750
+المضلة أبلونجاتا و ال midbrain help regulate rate
+
+144
+00:10:41,750 --> 00:10:44,950
+and depth of breathing بتتحكم ال bones بتتحكم في
+
+145
+00:10:44,950 --> 00:10:50,730
+ال breathing و release nervous impulse to and from
+
+146
+00:10:50,730 --> 00:10:54,530
+المضلة أبلونجاتا and cerebellum بتحاول تعمل ترجمة
+
+147
+00:10:54,850 --> 00:11:02,690
+أو تفسير لل sensory impulse اللى جاية من مجلة أو
+
+148
+00:11:02,690 --> 00:11:06,370
+السرب اللىأما المدلة ابلنجاتا فهي enlarged
+
+149
+00:11:06,370 --> 00:11:11,290
+continuation of the spinal cord هي عبارة عن المدلة
+
+150
+00:11:11,290 --> 00:11:14,370
+ابلنجاتا هي الوصلة ما بين ال brain و بين ال spinal
+
+151
+00:11:14,370 --> 00:11:19,770
+cord conducts ascending and descending impulses
+
+152
+00:11:19,770 --> 00:11:22,770
+يعني في impulse سارع للدمغ و في impulse نازلة من
+
+153
+00:11:22,770 --> 00:11:25,930
+الدماغ between the brain and spinal cord يعني هي
+
+154
+00:11:25,930 --> 00:11:29,510
+عملية حلقة الوصل ما بين ال brain و بين ال spinal
+
+155
+00:11:29,510 --> 00:11:33,760
+cord عن طريق elevator ساعد و elevatorNasal
+
+156
+00:11:33,760 --> 00:11:39,120
+Contains Cardiac و Vasomotor و Respiratory Control
+
+157
+00:11:39,120 --> 00:11:43,840
+Centers عشان هذه في حالات الشنق هي اللي بتأدي الى
+
+158
+00:11:43,840 --> 00:11:50,340
+الوفاة لإنها بتقطع الاتصال عن كل الأشياء الحيوية
+
+159
+00:11:50,340 --> 00:11:55,180
+أو المراكز الحيوية في الجسم زي القلب والأوائل
+
+160
+00:11:55,180 --> 00:11:59,910
+الدموية والتنفس فهي عملية الشنق بتصير عن طريقهامن
+
+161
+00:11:59,910 --> 00:12:04,230
+تفسر المدلة ابن جاتى عن ال brain من هذه المنطقة
+
+162
+00:12:04,230 --> 00:12:09,290
+فبتدى الوفع فورا Contains various non-verbal
+
+163
+00:12:09,290 --> 00:12:13,070
+reflex control زى ال coughing و ال sneezing و ال
+
+164
+00:12:13,070 --> 00:12:18,850
+swallowing و ال vomiting يعنى السؤال و العطس و
+
+165
+00:12:18,850 --> 00:12:25,870
+البلاء و التقيق و غيره أما ال cerebellumفهو
+
+166
+00:12:25,870 --> 00:12:28,970
+inferior to the occipital lobe تحت الـ occipital
+
+167
+00:12:28,970 --> 00:12:32,170
+lobe of the cerebrum posterior to the bones and
+
+168
+00:12:32,170 --> 00:12:38,690
+medulla oblongata زي ما احنا شايفينه بهذا الشكل،
+
+169
+00:12:38,690 --> 00:12:42,510
+هاي الـ cerebellum بقالوا برضه two hemispheres زي
+
+170
+00:12:42,510 --> 00:12:48,010
+الcerebellum وقالوا vermins connect ال hemisphere
+
+171
+00:12:48,010 --> 00:12:53,570
+في وصلة ما بين ال hemisphere cerebral cortex بتكون
+
+172
+00:12:53,570 --> 00:13:00,300
+من a gray matterكمان و Airport فيتي للـ White
+
+173
+00:13:00,300 --> 00:13:04,360
+Matter وCerebellar peduncles nerve fibers tracks
+
+174
+00:13:04,360 --> 00:13:09,820
+وDentate دونتويد نيوكلياس large هي ال largest
+
+175
+00:13:09,820 --> 00:13:13,520
+nucleus في الcerebellum هو طبيعي بيعمل integration
+
+176
+00:13:13,520 --> 00:13:17,200
+between sensory information اللي هي لعلاقة في
+
+177
+00:13:17,200 --> 00:13:20,660
+position of the body part اللي بيحافظ على التوازن
+
+178
+00:13:20,920 --> 00:13:25,680
+الجسم هو ال coordination skeletal muscle activity
+
+179
+00:13:25,680 --> 00:13:29,460
+وبيحافظ على البشر طبعا الشخص اللي بيكون فيه عنده
+
+180
+00:13:29,460 --> 00:13:32,980
+مشكلة في ال cerebellum بيعاني من حاجة اسمها ataxia
+
+181
+00:13:32,980 --> 00:13:37,260
+ال ataxia هي lack of coordination لأن الجسم دائما
+
+182
+00:13:37,260 --> 00:13:44,040
+بيترنح وهذا شكل ال cerebellum زي ما احنا شايفينه
+
+183
+00:13:44,040 --> 00:13:47,180
+posterior to the bone
+
+184
+00:13:49,830 --> 00:13:55,790
+و هذا خلينا شكل توضيحي لكل أجزاء ال brain، فيكوا
+
+185
+00:13:55,790 --> 00:14:00,570
+أنه تقرأوه ببرحتكوا، هنا ال cerebellum و ال
+
+186
+00:14:00,570 --> 00:14:06,950
+thalamus و ال hypothalamus و ال bones و ال medulla
+
+187
+00:14:06,950 --> 00:14:10,790
+oblongata و ال cerebral hemisphere و كل واحدة مع
+
+188
+00:14:10,790 --> 00:14:15,450
+ال function هذه بصراحة ال slide بكل المحاضرة اللي
+
+189
+00:14:15,450 --> 00:14:19,430
+احنا بتكلم عن ال function of different parts of
+
+190
+00:14:19,430 --> 00:14:23,330
+brainأما ال cranial nerves فقولنا زي ما في عندنا
+
+191
+00:14:23,330 --> 00:14:25,670
+spinal nerve في عندنا cranial nerve because ال
+
+192
+00:14:25,670 --> 00:14:29,930
+upper part of the body ال head و ال neck و ال .. و
+
+193
+00:14:29,930 --> 00:14:33,630
+ال jaw و ال swallowing و hair و طبعا في عندنا
+
+194
+00:14:33,630 --> 00:14:37,970
+dwell pairs of cranial nerve بتبدأ في أول cranial
+
+195
+00:14:37,970 --> 00:14:43,950
+nerve هو الفكتوري و الشمو ال .. ال .. ال optic و
+
+196
+00:14:43,950 --> 00:14:48,850
+ال oculomotor و ال procular و ال trigeminal و ال
+
+197
+00:14:48,850 --> 00:14:52,910
+abducens و ال facial و العصب السابع اللي دايما
+
+198
+00:14:52,910 --> 00:14:57,670
+بيصير فيه مشاكل أو بيصير فيه بيسموها لفة الوجه و
+
+199
+00:14:57,670 --> 00:15:01,590
+glossopharyngeal و ال accessory فيه عند العصب
+
+200
+00:15:01,590 --> 00:15:05,810
+العاشر هو ال Vegas اللي احنا شايفينهوالـ
+
+201
+00:15:05,810 --> 00:15:10,730
+Hypocholestial و ال vestibular و ال cochlear و ال
+
+202
+00:15:10,730 --> 00:15:17,670
+.. هيك بيكونوا كلهم تقريبا طبعا أنا ال meninges of
+
+203
+00:15:17,670 --> 00:15:21,870
+the brain ففي عندنا three layers of meninges اللي
+
+204
+00:15:21,870 --> 00:15:25,530
+بتسمع الحاجة اسمها meninges هيش وظيفة ال meninges
+
+205
+00:15:25,530 --> 00:15:28,630
+و قلتها بنسميها الصحة طب هذه ال meninges هيش
+
+206
+00:15:28,630 --> 00:15:31,670
+وظيفتها و وظيفتها تلاتة layer من ال meninges
+
+207
+00:15:31,670 --> 00:15:38,430
+بتساعد على حماية ال brainبتعمل زي غشاء بيحمي
+
+208
+00:15:38,430 --> 00:15:42,850
+البران وغشاء هذا موجود في ال CSF بيحمي البران من
+
+209
+00:15:42,850 --> 00:15:47,010
+الصدمة طبعا تلاتة layers ال durable matter ال
+
+210
+00:15:47,010 --> 00:15:50,690
+outer أو ال tough أو بيسموه الأم الجافية ال
+
+211
+00:15:50,690 --> 00:15:55,030
+arachnoid matter هو thin و whoop like أما ال
+
+212
+00:15:55,030 --> 00:15:59,050
+biomatter فهي ال inner peritone بيسموهبالأم الحنون
+
+213
+00:15:59,050 --> 00:16:04,030
+لإن هو ملاصق لخلايا
+
+214
+00:16:04,030 --> 00:16:08,150
+ال brain وهذه الخلايا أثناء العمليات الجراحية
+
+215
+00:16:08,150 --> 00:16:13,890
+المنجيز اللي بتتم فتحها عشان يدخلوا لبراين وهنا زي
+
+216
+00:16:13,890 --> 00:16:17,690
+ما احنا شايفين ال virus والسلكال of the brain
+
+217
+00:16:17,690 --> 00:16:21,590
+وشايفين كيف في عندنا blood vessels
+
+218
+00:16:23,810 --> 00:16:26,910
+طبعا فى لإن ال spinal meninges برضه فى عندنا
+
+219
+00:16:26,910 --> 00:16:29,810
+الديورة ال top فى اللى بنسميه ال mother strong ال
+
+220
+00:16:29,810 --> 00:16:34,090
+arachnoid هذا الخارجى اللى صعب أنه ينفتح وفى عندنا
+
+221
+00:16:34,090 --> 00:16:40,710
+ال arachnoid فى spider looking عامل زى كأنه spider
+
+222
+00:16:40,710 --> 00:16:47,530
+عن كبوتى اكرد blood vessels وفى عندنا subarachnoid
+
+223
+00:16:47,530 --> 00:16:49,950
+ال space اللى تحت ال arachnoid وفى عندنا ال
+
+224
+00:16:49,950 --> 00:16:53,530
+diameterاللي هي delicate mother adhered tightly to
+
+225
+00:16:53,530 --> 00:16:56,370
+the surface of the spinal cord نفس الـMeninges هذه
+
+226
+00:16:56,370 --> 00:17:00,330
+اللي في الإبراهيم في عين الفنتركلز اللي هي الفجوات
+
+227
+00:17:00,330 --> 00:17:06,010
+اللي موجودة بتعمل connection عبارة هي عن تجاويف
+
+228
+00:17:06,010 --> 00:17:09,650
+مترابطة within the cerebral hemisphere and brain
+
+229
+00:17:09,650 --> 00:17:14,670
+stem وتمتد continuously with the central canal of
+
+230
+00:17:14,670 --> 00:17:18,870
+the spinal cord وفيها مليئة بالcerebral spinal
+
+231
+00:17:18,870 --> 00:17:26,000
+fluid اللي هو CSFهي ال largest in the cerebellum
+
+232
+00:17:26,000 --> 00:17:31,040
+في عندنا lateral ventricle في عندنا right and left
+
+233
+00:17:31,040 --> 00:17:34,100
+في عندنا التالتة اللي هي third ventricle في الدين
+
+234
+00:17:34,100 --> 00:17:37,820
+السفلان و between right and left thalamus وفي
+
+235
+00:17:37,820 --> 00:17:40,700
+عندنا الرابعة ال fourth ventricle post bones
+
+236
+00:17:40,700 --> 00:17:46,410
+وcerebral aqueducts third and fourth ventriclesالـ
+
+237
+00:17:46,410 --> 00:17:50,350
+cerebrospinal fluid هو عبارة عن fluid secreted by
+
+238
+00:17:50,350 --> 00:17:55,690
+a choroid plexus، circulates in the ventricle,
+
+239
+00:17:55,770 --> 00:17:58,570
+central canal of the spinal cord and subarachnoid
+
+240
+00:17:58,570 --> 00:18:03,040
+space وفي الـ CSF دائما، إيش بتعطينا؟الـ nutrition
+
+241
+00:18:03,040 --> 00:18:06,340
+و ال protection كمان هو عبارة عن clear liquids
+
+242
+00:18:06,340 --> 00:18:12,200
+يعني سائل شفاف بيحيط ال spinal cord and ال brain
+
+243
+00:18:12,200 --> 00:18:16,640
+كمان بيساعد على ال stability لل ions فيه و ال
+
+244
+00:18:16,640 --> 00:18:21,090
+concentration في ال central nervous systemوال ..
+
+245
+00:18:21,090 --> 00:18:25,670
+في عندنا formula like او linked between ventricles
+
+246
+00:18:25,670 --> 00:18:29,970
+وفي interventriculars, ventricles, formula linked
+
+247
+00:18:29,970 --> 00:18:35,730
+between third and lateral ventricles وهذه طبعا ال
+
+248
+00:18:35,730 --> 00:18:39,930
+style الأخيرة معانا في هذه المحاضرة نسمع كتير عن
+
+249
+00:18:39,930 --> 00:18:43,350
+lumber puncture ال lumber puncture بتاخد خليني
+
+250
+00:18:43,350 --> 00:18:50,390
+أقول غزعة أو كمية من ال ..الـ CSF بتتم فحصها خاصة
+
+251
+00:18:50,390 --> 00:18:57,090
+في حالات الـ meningitis وكمان بيصير في أحيان
+
+252
+00:18:57,090 --> 00:19:01,010
+المناقشة ال epidural من الانستيزيا فبيدخلولها من
+
+253
+00:19:01,010 --> 00:19:06,710
+هذه المنطقة يعطيكم العافية و ان شاء الله بتبقى
+
+254
+00:19:06,710 --> 00:19:09,570
+عندنا المحاضرة الأخيرة عن ال spinal cord ان شاء
+
+255
+00:19:09,570 --> 00:19:10,270
+الله رب العالمين
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/-rkSaY6nWL8.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/-rkSaY6nWL8.srt
new file mode 100644
index 0000000000000000000000000000000000000000..756344e92019d1c4a14653e26f9afb0894e5b0a9
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/-rkSaY6nWL8.srt
@@ -0,0 +1,2054 @@
+1
+00:00:01,740 --> 00:00:06,180
+بسم الله الرحمن الرحيم موضوعنا إن شاء الله الـ
+
+2
+00:00:06,180 --> 00:00:10,420
+Autoimmune Diseases راح نحكي عنها بإيجاز وراح
+
+3
+00:00:10,420 --> 00:00:12,740
+نحكي عن الـ Diagnosis  الطبية لها بالنسبة للـ
+
+4
+00:00:12,740 --> 00:00:16,280
+Autoimmune Diseases  الـ Autoimmune Diseases هي
+
+5
+00:00:16,280 --> 00:00:19,980
+عبارة عن مجموعة من الأمراض التي بيصير فيها tissue
+
+6
+00:00:19,980 --> 00:00:24,540
+injury نتيجة ما يُعرف بالـ humoral أو الـ cell-mediated
+
+7
+00:00:24,540 --> 00:00:28,020
+immune response الذي يكون directed للـ self
+
+8
+00:00:28,020 --> 00:00:32,860
+-antigens.عادةً الـ Immune System كما نعلم
+
+9
+00:00:32,860 --> 00:00:35,580
+لديه القدرة على تمييز الـ Self عن الـ Non-Self
+
+10
+00:00:35,580 --> 00:00:38,840
+Antigen. لكن بالرغم من هذا، لدينا مجموعة كبيرة من
+
+11
+00:00:38,840 --> 00:00:41,740
+الـ Autoimmune Diseases التي فيها الـ Immune
+
+12
+00:00:41,740 --> 00:00:47,820
+System يهاجم الـ Self-Antigen أو Self-Cells.
+
+13
+00:00:47,820 --> 00:00:51,440
+الـ Attack can be directed either against a very
+
+14
+00:00:51,440 --> 00:00:55,040
+specific tissue أو a large number of tissues. يعني
+
+15
+00:00:55,040 --> 00:00:58,440
+المشكلة أو الـ Antibodies أو الـ Immune Response
+
+16
+00:00:58,440 --> 00:01:03,470
+الذي يتكون قد يكون مخصصًا لنسيج معين أو لنوع معين من
+
+17
+00:01:03,470 --> 00:01:08,510
+الخلايا أو أنه يهاجم أكثر من نوع من الأنسجة. once
+
+18
+00:01:08,510 --> 00:01:12,930
+started. بمجرد ما تبدأ  أمراض المناعة الذاتية
+
+19
+00:01:12,930 --> 00:01:16,850
+صعب جداً علاجها. وُضعت بعض التفسيرات التي قد
+
+20
+00:01:16,850 --> 00:01:22,570
+تكون صحيحة وقد يكون فيها بعض الغموض.
+
+21
+00:01:22,570 --> 00:01:28,470
+لحدوث أمراض المناعة الذاتية. بدايةً، يُقال إن
+
+22
+00:01:28,470 --> 00:01:32,650
+ممكن تتكون أمراض المناعة الذاتية نتيجة وجود بعض
+
+23
+00:01:32,650 --> 00:01:35,630
+الـ sequestered or hidden antigens.  يعني antigens
+
+24
+00:01:35,630 --> 00:01:40,150
+موجودة في الجسم لكن في مكان معزول، بمعنى أنه لا يوجد
+
+25
+00:01:40,150 --> 00:01:44,490
+contact بينها وبين جهاز المناعة مباشرةً. فمن الممكن
+
+26
+00:01:44,490 --> 00:01:47,950
+في لحظة ما، أن يُدرك جهاز المناعة أنها
+
+27
+00:01:47,950 --> 00:01:51,010
+بالنسبة إليه foreign antigens.  مثل الـ antigens
+
+28
+00:01:51,010 --> 00:01:55,290
+مثل الـ lens antigen،  sperm antigen و الـ cyroglobin.
+
+29
+00:01:55,290 --> 00:02:00,730
+تمام؟  هناك  نوع آخر يُسمى neo-antigens في الجسم.
+
+30
+00:02:00,730 --> 00:02:04,850
+كيف تتكون الـ neo-antigens؟  الـ
+
+31
+00:02:04,850 --> 00:02:08,090
+antigens العادية الموجودة في الجسم أساساً، من الممكن
+
+32
+00:02:08,090 --> 00:02:12,730
+أن تتعرض لتعديل نتيجة التعرض لإشعاع أو
+
+33
+00:02:12,730 --> 00:02:16,050
+لعوامل فيزيائية معينة،  مثل الإشعاع، أو لبعض الـ chemicals
+
+34
+00:02:16,050 --> 00:02:20,010
+مثل الأدوية، أو لبعض الـ microbes، خاصةً الـ
+
+35
+00:02:20,010 --> 00:02:23,610
+intracellular viruses.  مما يُسبب تغيرًا في الـ antigens
+
+36
+00:02:23,610 --> 00:02:27,540
+الموجودة على غشاء الخلية. وبالتالي، يتعرف عليها الجسم
+
+37
+00:02:27,540 --> 00:02:32,720
+على أنها Foreign Antigens. cessation of tolerance. طبعاً
+
+38
+00:02:32,720 --> 00:02:38,240
+نعلم أن الجسم يُظهر تقبلاً  للـ self
+
+39
+00:02:38,240 --> 00:02:41,700
+-antigen.  فمن الممكن أن يتوقف هذا التقبل.
+
+40
+00:02:41,700 --> 00:02:45,700
+السبب الرابع، هو وجود cross
+
+41
+00:02:45,700 --> 00:02:49,060
+-reacting antigens.  ماذا يعني cross-reacting
+
+42
+00:02:49,060 --> 00:02:53,110
+antigens؟  أن هناك Foreign Antigens. هذه الـ Foreign
+
+43
+00:02:53,110 --> 00:02:57,450
+Antigens تشبه بعض الـ Antigens الموجودة في الجسم.
+
+44
+00:02:57,450 --> 00:03:01,550
+عندما يُكوّن الجسم Antibodies، هذه الـ Antibodies
+
+45
+00:03:01,550 --> 00:03:04,810
+ستعمل Cross-reacting  بين الـ Foreign
+
+46
+00:03:04,810 --> 00:03:08,710
+Antigen و بين الـ Human أو الـ Self Antigen.
+
+47
+00:03:08,710 --> 00:03:13,930
+ينتج عن هذا نوع من المناعة الذاتية. طبعاً، هنا
+
+48
+00:03:13,930 --> 00:03:17,030
+يُقال: Many species share organ specific antigens.
+
+49
+00:03:17,030 --> 00:03:20,210
+هناك العديد من الأنواع،  أو species
+
+50
+00:03:20,210 --> 00:03:23,920
+متعددة، قد يكون هناك تشابه في بعض الـ organ
+
+51
+00:03:23,920 --> 00:03:28,860
+-specific antigens.  مثال:  الـ human brain و الـ
+
+52
+00:03:28,860 --> 00:03:32,880
+antigens of sheep brain.  هناك تشابه.  هناك نقطة أخرى،
+
+53
+00:03:32,880 --> 00:03:35,680
+الـ streptococcal unprotein and heart
+
+54
+00:03:35,680 --> 00:03:40,880
+muscles. لذلك، إذا تعرّض الإنسان لإصابة بـ
+
+55
+00:03:40,880 --> 00:03:43,260
+streptococci،  هناك احتمال أن الـ antibody الذي
+
+56
+00:03:43,260 --> 00:03:47,280
+يتكون يهاجم الـ heart muscle. nephretogenic
+
+57
+00:03:47,280 --> 00:03:51,660
+strains of streptococci antigens.  من الممكن أن الـ
+
+58
+00:03:51,660 --> 00:03:55,560
+Antigens هذه تتشابه مع الـ Renal Glomeruli
+
+59
+00:03:55,560 --> 00:03:59,780
+Epitopes أو Antigens على الخلايا. بالتالي،
+
+60
+00:03:59,780 --> 00:04:03,120
+لو تكوّن Antibody،  من الممكن أن يحدث cross-reacting بين
+
+61
+00:04:03,120 --> 00:04:08,760
+هما. Loss of immune regulation.  قلنا قبل قليل
+
+62
+00:04:08,760 --> 00:04:12,800
+أن في بعض الأحيان، من الممكن أن يتوقف تقبّل الـ Self
+
+63
+00:04:12,800 --> 00:04:17,560
+-antigen. هذا طبعاً مشكلة.
+
+64
+00:04:19,330 --> 00:04:24,430
+وقد يكون ذلك بسبب فرط النشاط أو انخفاض النشاط لـ
+
+65
+00:04:24,430 --> 00:04:31,550
+T و B الخلايا. Classification
+
+66
+00:04:31,550 --> 00:04:34,430
+of autoimmune diseases.  أمراض المناعة الذاتية قد
+
+67
+00:04:34,430 --> 00:04:38,090
+تكون hemolytic، أي تصيب خلايا الدم.  نوعان:
+
+68
+00:04:38,090 --> 00:04:43,190
+localized، أي خاصة بنوع معين من الخلايا، أو
+
+69
+00:04:43,190 --> 00:04:46,950
+systemic،  أي تصيب أكثر من عضو في الجسم.
+
+70
+00:04:50,570 --> 00:04:53,210
+النوع الأول: «Hemolytic Autoimmune
+
+71
+00:04:53,210 --> 00:04:58,970
+Diseases».  وهو اضطراب سريري ناتج عن
+
+72
+00:04:58,970 --> 00:05:01,350
+destruction of blood components.  من الممكن تكون
+
+73
+00:05:01,350 --> 00:05:04,990
+auto-antibodies لخلايا الدم الحمراء،  الخلايا البيضاء،  و الصفيحات الدموية.
+
+74
+00:05:04,990 --> 00:05:07,870
+ينتج عن ذلك فقر دم انحلالي،  قلة الكريات البيضاء،
+
+75
+00:05:07,870 --> 00:05:10,550
+قلة الصفيحات الدموية.  النوع الثاني:
+
+76
+00:05:10,550 --> 00:05:14,790
+«Localized Autoimmune Diseases».  يطلق عليها أيضاً
+
+77
+00:05:14,790 --> 00:05:19,650
+organ specific autoimmune diseases. تكون الـ
+
+78
+00:05:19,650 --> 00:05:23,630
+Antibodies موجهة لنوع معين من الخلايا الموجودة في
+
+79
+00:05:23,630 --> 00:05:27,590
+هذا العضو.  ينتج عن ذلك نوع من أنواع
+
+80
+00:05:27,590 --> 00:05:34,010
+أمراض المناعة الذاتية. من الأمثلة الشهيرة
+
+81
+00:05:34,010 --> 00:05:37,950
+عليها التهاب الغدة الدرقية.  Thyroiditis Antibodies
+
+82
+00:05:37,950 --> 00:05:42,410
+تهاجم الغدة الدرقية.  التصلب المتعدد. Multiple
+
+83
+00:05:42,410 --> 00:05:46,150
+sclerosis.  عبارة عن مرض يُسمّى التصلب اللويحي.
+
+84
+00:05:46,880 --> 00:05:51,020
+هنا، تتكون Antibodies لغمد الميالين المحيط بالـ
+
+85
+00:05:51,020 --> 00:05:53,760
+الخلايا العصبية.  نعلم أن غمد الميالين هذا
+
+86
+00:05:53,760 --> 00:05:58,800
+وظيفته تسريع الإشارات العصبية. إذا تكونت Auto
+
+87
+00:05:58,800 --> 00:06:03,780
+Antibodies لغمد الميالين، ستبطئ الإشارات العصبية
+
+88
+00:06:03,780 --> 00:06:08,960
+لأن غمد الميالين سيُفقد وظيفته، وسيبدأ
+
+89
+00:06:08,960 --> 00:06:14,990
+ظهور مشاكل متعددة في الأعصاب.  وهناك مرض عضلي، الوهن العضلي الوبيل Myasthenia gravis
+
+90
+00:06:14,990 --> 00:06:20,810
+هنا، تحدث مشكلة في منطقة اتصال العصب بالعضلة.
+
+91
+00:06:20,810 --> 00:06:25,110
+attack  للـ nerve muscle
+
+92
+00:06:25,110 --> 00:06:29,490
+junction، وهي منطقة اتصال العصب بالعضلة.  داء السكري من النوع الأول، juvenile diabetes or type 1 diabetes
+
+93
+00:06:29,490 --> 00:06:34,030
+تتكون antibodies للخلايا المنتجة للأنسولين.  ومرض آخر،  الذئبة الحمامية الجهازية، مرض الاضطرابات الهضمية
+
+94
+00:06:34,030 --> 00:06:35,870
+آخر،  وهو داء السيلياك celiac disease
+
+95
+00:06:38,770 --> 00:06:41,790
+النوع الثالث: Systemic Autoimmune Diseases.  الـ Systemic
+
+96
+00:06:41,790 --> 00:06:45,710
+Autoimmune Diseases تُسمى عادةً Non-Organ Specific
+
+97
+00:06:45,710 --> 00:06:48,930
+Autoimmune Diseases. حيث تتجمع  Immune Complexes
+
+98
+00:06:48,930 --> 00:06:53,090
+وتتكون ضد أنسجة مختلفة، وتسبب
+
+99
+00:06:53,090 --> 00:06:57,010
+التهابًا وتلفًا. طبعاً هذا سيؤثر على أعضاء
+
+100
+00:06:57,010 --> 00:07:01,650
+متعددة في الجسم.  من الأمثلة، الذئبة الحمامية الجهازية Systemic Lupus. حيث
+
+101
+00:07:01,650 --> 00:07:05,430
+أن الـ Antibody  الذي يتكون يكون Antinuclear،  أي ضد النواة.
+
+102
+00:07:05,430 --> 00:07:10,200
+أي مكان به نواة سيتكون ضده أجسام مضادة.  يُصيب الكلى، Harm Kidneys,
+
+103
+00:07:10,440 --> 00:07:15,880
+القلب، الدماغ، الرئتين، والجلد.  من الأمثلة الأخرى
+
+104
+00:07:15,880 --> 00:07:18,600
+الروماتويد Rheumatoid Arthritis.  Rheumatoid
+
+105
+00:07:18,600 --> 00:07:23,200
+Arthritis، كما ذكرنا، عبارة عن Anti-IgG
+
+106
+00:07:23,200 --> 00:07:26,720
+Antibodies.  سيُصيب المفاصل، القلب، الرئتين،
+
+107
+00:07:26,880 --> 00:07:31,080
+الجهاز العصبي. الحمى الروماتيزمية Rheumatic Fever.
+
+108
+00:07:31,080 --> 00:07:35,180
+التي ذكرناها،  يكون ASOT فيها
+
+109
+00:07:35,180 --> 00:07:38,860
+موجبة.  يحدث تفاعل متبادل بين Antibodies
+
+110
+00:07:38,860 --> 00:07:42,160
+الـ Streptococcus  و Auto-antibodies.  داء السيلياك
+
+111
+00:07:42,160 --> 00:07:46,720
+Celiac Disease.  هو مرض معروف بحساسية القمح.
+
+112
+00:07:46,720 --> 00:07:51,260
+يُسمى أيضاً Celiac Sprew أو Gluten Sensitive
+
+113
+00:07:51,260 --> 00:07:54,900
+Enteropathy.  هو اضطراب مناعي هضمي
+
+114
+00:07:54,900 --> 00:07:58,340
+يؤدي إلى تلف بطانة الأمعاء الدقيقة
+
+115
+00:07:58,340 --> 00:08:02,020
+عند تناول الأطعمة المحتوية على الغلوتين.  عندما
+
+116
+00:08:02,020 --> 00:08:06,500
+يتناول الشخص المصاب طعامًا يحتوي على
+
+117
+00:08:06,500 --> 00:08:10,140
+الغلوتين،  يحدث تلف في الزغابات المعوية،
+
+118
+00:08:10,140 --> 00:08:13,360
+التي تمتص الطعام.  ما هو الغلوتين؟
+
+119
+00:08:13,360 --> 00:08:16,080
+هو نوع من البروتينات الموجودة في بعض الـ
+
+120
+00:08:16,080 --> 00:08:19,160
+الحبوب. تلف الأمعاء يجعل
+
+121
+00:08:19,160 --> 00:08:22,220
+من الصعب على الجسم امتصاص العناصر الغذائية.
+
+122
+00:08:22,220 --> 00:08:25,020
+تخيلوا الزغابات المعوية الطبيعية،
+
+123
+00:08:25,020 --> 00:08:28,810
+الطبيعية،  عند الإصابة بداء السيلياك،  يحدث
+
+124
+00:08:28,810 --> 00:08:31,690
+ضمور فيها.  وبالتالي، لن تتمكن من امتصاص العناصر
+
+125
+00:08:31,690 --> 00:08:36,570
+الغذائية المهمة، خاصة الدهون، الكالسيوم، الحديد،
+
+126
+00:08:36,570 --> 00:08:38,670
+الكوليسترول.  ما سبب داء السيلياك؟
+
+127
+00:08:38,670 --> 00:08:42,710
+عندما يتناول المصابون بهذا المرض طعامًا يحتوي على
+
+128
+00:08:42,710 --> 00:08:46,410
+الغلوتين،  ينتج جهاز المناعة لديهم أجسامًا مضادة للـ
+
+129
+00:08:46,410 --> 00:08:49,850
+الغلوتين.  تكون أجسام مضادة لهذا البروتين.
+
+130
+00:08:49,850 --> 00:08:53,570
+هذه الأجسام المضادة ستهاجم بطانة الأمعاء.
+
+131
+00:08:53,570 --> 00:08:57,600
+هذا يسبب التهابًا في
+
+132
+00:08:57,600 --> 00:09:00,800
+الأمعاء، ويضر بالزغابات المعوية.  يُسبب
+
+133
+00:09:00,800 --> 00:09:04,980
+التهابًا  ويُلحق الضرر بالزغابات.  ما هي الزغابات؟
+
+134
+00:09:04,980 --> 00:09:08,200
+هي هياكل تشبه الشعر على بطانة
+
+135
+00:09:08,200 --> 00:09:11,700
+الأمعاء الدقيقة.  تتم امتصاص العناصر الغذائية من الطعام عادةً بواسطة الزغابات.
+
+136
+00:09:11,700 --> 00:09:15,380
+نعلم أن العناصر الغذائية تُمتص في الزغابات.  إذا
+
+137
+00:09:15,380 --> 00:09:18,340
+تضررت الزغابات،  لن يتمكن هذا الشخص من
+
+138
+00:09:18,340 --> 00:09:21,960
+امتصاص العناصر الغذائية،  وسيُصاب بسوء التغذية.  بغض
+
+139
+00:09:21,960 --> 00:09:26,300
+النظر لكمية العناصر الغذائية المتناولة،  لا يوجد امتصاص،  لذلك
+
+140
+00:09:30,300 --> 00:09:34,720
+لن يستفيد منها. Symptoms
+
+141
+00:09:34,720 --> 00:09:40,260
+of Celiac Disease.  الأعراض تختلف من شخص لآخر.
+
+142
+00:09:40,260 --> 00:09:46,620
+تختلف حسب شدة الأعراض. بدايةً،  مشاكل هضمية،  انتفاخات في البطن، Abdominal Bloating
+
+144
+00:09:50,820 --> 00:09:54,660
+ألم،  غازات،  إسهال،  براز دهني،  وفقدان الوزن.
+
+145
+00:09:54,660 --> 00:09:55,370
+و أيضاً،
+
+146
+00:09:55,370 --> 00:10:01,270
+طفح جلدي حاد يُسمى  dermatitis herpetiformis.
+
+147
+00:10:01,270 --> 00:10:04,570
+يحدث طفح جلدي.  فقر الدم الناتج عن نقص الحديد.
+
+148
+00:10:04,570 --> 00:10:07,930
+بعد تناول الحبوب المحتوية على الغلوتين،  سيظهر
+
+149
+00:10:07,930 --> 00:10:10,710
+هذه الأعراض. فقر الدم الناتج عن نقص الحديد نتيجة سوء
+
+150
+00:10:10,710 --> 00:10:15,730
+الامتصاص.  مشاكل في الجهاز العضلي الهيكلي، تشنجات عضلية،
+
+151
+00:10:15,730 --> 00:10:19,450
+المفاصل،  والعظام.  لماذا؟  لأن هناك نقصًا في العناصر
+
+152
+00:10:19,450 --> 00:10:23,390
+الغذائية، نقص في الكالسيوم، نقص في الأشياء الضرورية لـ
+
+153
+00:10:23,390 --> 00:10:27,060
+عمل العضلات،  والعظام،  والمفاصل بشكل صحيح.  مشاكل النمو،
+
+154
+00:10:27,060 --> 00:10:32,000
+وانعدام النمو.  يحدث صعوبة في النمو عند الأطفال. وخز، tingling
+
+155
+00:10:35,160 --> 00:10:39,580
+إحساس بالوخز في الساقين.
+
+156
+00:10:39,580 --> 00:10:45,460
+يحدث تنمل في الساقين.  هذا ناتج عن نقص الكالسيوم،
+
+157
+00:10:45,460 --> 00:10:51,020
+سيؤثر على العضلات.  قروح فموية مؤلمة، Obsess ulcers sore in
+
+158
+00:10:57,230 --> 00:11:01,570
+الفم.  تكرار حدوث قروح في الفم.  انقطاع الطمث، missed
+
+159
+00:11:01,570 --> 00:11:04,470
+menstrual period.  بالنسبة للإناث،  ستجدين أن
+
+160
+00:11:04,470 --> 00:11:08,990
+الدورة الشهرية غير منتظمة،  أو
+
+161
+00:11:08,990 --> 00:11:15,370
+فترات طويلة.  هناك مشاكل صحية مصاحبة، health problems accompany
+
+162
+00:11:15,370 --> 00:11:17,950
+داء السيلياك.  داء السيلياك قد يجعل الشخص
+
+163
+00:11:17,950 --> 00:11:21,750
+عرضة لمشاكل صحية أخرى.  مضاعفات
+
+164
+00:11:21,930 --> 00:11:25,270
+مثل هشاشة العظام Osteoporosis.  هشاشة العظام، نتيجة سوء
+
+165
+00:11:25,270 --> 00:11:30,950
+الامتصاص.  هشاشة العظام. لماذا؟ لأن هذا الشخص لا يتمكن من امتصاص
+
+166
+00:11:30,950 --> 00:11:35,610
+الكالسيوم أو فيتامين د بشكل جيد، وهما مهمان جدًا لبناء
+
+167
+00:11:35,610 --> 00:11:38,510
+العظام.  الإجهاض أو العقم، Miscarriage أو Infertility.
+
+168
+00:11:42,370 --> 00:11:48,300
+عيوب خلقية Birth Defects.  لأن الجنين أثناء الحمل
+
+169
+00:11:48,300 --> 00:11:53,120
+يحتاج إلى عناصر غذائية لتكوّنه بشكل سليم.  هؤلاء الأشخاص لديهم
+
+170
+00:11:53,120 --> 00:11:56,620
+سوء تغذية.  النساء الحوامل لديهن
+
+171
+00:11:56,620 --> 00:12:00,260
+سوء تغذية.  وبالتالي،  لن تصل للجنين الكميات
+
+172
+00:12:00,260 --> 00:12:03,880
+الغذائية الكافية اللازمة لنموه.  سيكون لديه عيوب خلقية، birth
+
+173
+00:12:03,880 --> 00:12:09,060
+defects، خاصةً عيوب الأنبوب العصبي neural tube defects.  عيوب الأنبوب العصبي
+
+174
+00:12:09,060 --> 00:12:12,450
+neural tube defects مرتبطة بنقص حمض الفوليك. لذلك
+
+175
+00:12:12,450 --> 00:12:15,410
+يُنصح النساء الحوامل بتناول حمض الفوليك لأنه
+
+176
+00:12:15,410 --> 00:12:19
+
+223
+00:15:24,720 --> 00:15:29,120
+وتكون Antibodies لهذا النوع من الـ لهذا الغشاء
+
+224
+00:15:29,120 --> 00:15:32,960
+اللي هو الـ Endometrium تمام؟ في عندي شغلة تانية
+
+225
+00:15:32,960 --> 00:15:38,220
+اللي هو Anti-reticulin antibody (ARA), not as
+
+226
+00:15:38,220 --> 00:15:41,200
+specific or sensitive as the other autoantibodies.
+
+227
+00:15:41,200 --> 00:15:45,260
+احنا لحد فترة قريبة كنا نعمل الـ Anti-endometrial
+
+228
+00:15:45,260 --> 00:15:49,600
+antibody، بس صحيح الـ kit بتاعه من عندنا خلص، إن شاء
+
+229
+00:15:49,600 --> 00:15:53,320
+الله، يعني نتأمل أنه يجي لأن هو بنعمل fluorescence
+
+230
+00:15:53,320 --> 00:15:58,480
+وحتى لو ما عملناهاش، فيه عندنا شرايح محفوظة، إن شاء الله
+
+231
+00:15:58,480 --> 00:16:07,620
+بتكون نتائجها كويسة، بنورّجيكم النتائج بتاعت الفحص، طيب.
+
+232
+00:16:07,620 --> 00:16:11,960
+Diagnosis of autoimmune diseases بشكل عام، أول حاجة
+
+233
+00:16:11,960 --> 00:16:15,820
+diagnosis of clinical symptoms, confirmed by
+
+234
+00:16:15,820 --> 00:16:18,820
+detecting the autoantibodies in the serum of the
+
+235
+00:16:18,820 --> 00:16:22,100
+patient. Autoantibodies are demonstrated by
+
+236
+00:16:22,100 --> 00:16:24,860
+immunofluorescence antibody test, hemagglutination,
+
+237
+00:16:24,860 --> 00:16:27,780
+complement fixation, immunodiffusion,
+
+238
+00:16:27,780 --> 00:16:30,700
+radioimmunoassay. لذَا أنا بدي أدور على الـ
+
+239
+00:16:30,700 --> 00:16:33,920
+autoantibodies بأحد التقنيات هذه، كل التقنيات هذه
+
+240
+00:16:33,920 --> 00:16:38,220
+تقريبًا حكينا عنها، بعد الـ immunofluorescence والـ
+
+241
+00:16:38,220 --> 00:16:40,640
+complement fixation، جاي إن شاء الله هنحكي عنهم
+
+242
+00:16:40,640 --> 00:16:47,940
+لقدام. نيجي لتقنية الـ Immunofluorescence Assay، الـ
+
+243
+00:16:47,940 --> 00:16:51,640
+Immunofluorescence Technique عبارة عن تقنية تسمح
+
+244
+00:16:51,640 --> 00:16:56,600
+لي أني أشوف بروتين أو أنتجين موجود في الـ tissue
+
+245
+00:16:56,600 --> 00:17:01,280
+section، يعني بيكون عندي tissue section، الـ tissue
+
+246
+00:17:01,280 --> 00:17:04,680
+section هذا أنا بدور فيه على بروتين أو على أنتجين
+
+247
+00:17:04,680 --> 00:17:08,660
+معيّن، عن طريق أني أنا بكون جاي بالـ Antibody
+
+248
+00:17:08,660 --> 00:17:13,120
+Antibody labelled بالـ fluorescein، الـ Fluorescein
+
+249
+00:17:13,120 --> 00:17:18,660
+Isothiocyanate، هذه عبارة عن صبغة تتميّز بأنه أنا
+
+250
+00:17:18,660 --> 00:17:22,820
+لما أسقط عليها الـ ultraviolet بتعطيني وميض أخضر
+
+251
+00:17:22,820 --> 00:17:27,100
+أو لون أخضر. The specific antibodies are labelled
+
+252
+00:17:27,100 --> 00:17:33,580
+with a compound, اللي هو Fluorescein Isothiocyanate,
+
+253
+00:17:33,580 --> 00:17:37,680
+that makes them glow a bright green color when
+
+254
+00:17:37,680 --> 00:17:40,640
+observed microscopically under ultraviolet
+
+255
+00:17:40,640 --> 00:17:44,620
+microscope. إذًا أنا بدور على Antigen أو Antibody فيه
+
+256
+00:17:44,620 --> 00:17:46,760
+الـ fluorescence. لما أجيب له Antibody ليه؟ فالـ
+
+257
+00:17:46,760 --> 00:17:51,480
+fluorescence هي خاصية لبعض الـ molecules اللي
+
+258
+00:17:51,480 --> 00:17:58,320
+بتِمتص ضوء بطول موجي معيّن. الآن لما بتمتص هذا الضوء
+
+259
+00:17:58,320 --> 00:18:03,180
+بيصير excitation للإلكترون إلى مستويات الطاقة أعلى
+
+260
+00:18:03,180 --> 00:18:07,480
+فلما بترجع الإلكترون إلى مستويات الطاقة الأولى
+
+261
+00:18:07,850 --> 00:18:12,790
+بتفقد طاقتها على شكل ضوء بطول موجي أعلى من اللي تَمّ
+
+262
+00:18:12,790 --> 00:18:18,110
+امتصاصه، فبتعطيني وميض أو وميدة. It is the property of
+
+263
+00:18:18,110 --> 00:18:22,930
+certain molecules, fluorophores, to absorb light
+
+264
+00:18:22,930 --> 00:18:25,890
+at one wavelength and emit light at a longer
+
+265
+00:18:25,890 --> 00:18:29,110
+wavelength; emission wavelengths when it is
+
+266
+00:18:29,110 --> 00:18:32,470
+illuminated by light of different wavelengths; excitation
+
+267
+00:18:32,470 --> 00:18:36,950
+wavelengths. يعني أنا بحط، بعرّضها لـ light
+
+268
+00:18:36,950 --> 00:18:40,410
+الـ light هذا يعمل لها excitation. The incident
+
+269
+00:18:40,410 --> 00:18:44,390
+light excites the molecules to a higher level of
+
+270
+00:18:44,390 --> 00:18:47,270
+vibrational energy، يعني بتعمل لها excitation
+
+271
+00:18:47,270 --> 00:18:51,770
+لمستويات طاقة أعلى. As the molecules return to the
+
+272
+00:18:51,770 --> 00:18:55,710
+ground state, the excited fluorophores emit a
+
+273
+00:18:55,710 --> 00:18:58,710
+photon; fluorescence emission. يعني لما بترجع
+
+274
+00:18:58,710 --> 00:19:02,310
+بتعطينا هذا. الـ fluorescence microscope موجود
+
+275
+00:19:02,310 --> 00:19:06,670
+عندنا، وإن شاء الله ربنا يعني بيسر الأمور وبنقدر
+
+276
+00:19:06,670 --> 00:19:10,370
+أن نشوف على الأقل العينات الموجودة الجاهزة عندنا
+
+277
+00:19:10,370 --> 00:19:16,050
+على الـ fluorescence microscope. Types
+
+278
+00:19:16,050 --> 00:19:20,550
+of immunofluorescence. أول حاجة فيه عندي direct
+
+279
+00:19:20,550 --> 00:19:24,380
+immunofluorescence staining, in which the primary
+
+280
+00:19:24,380 --> 00:19:27,320
+antibody is labelled with a fluorescent dye. يعني
+
+281
+00:19:27,320 --> 00:19:32,380
+فيه direct وفي indirect. الـ direct بعمل labelling للـ
+
+282
+00:19:32,380 --> 00:19:37,220
+antibody اللي بده يرتبط مباشرة بالـ antigen، وبعد هيك
+
+283
+00:19:37,220 --> 00:19:41,640
+طبعًا بعمل washing، بشيل أي Antibody ما صار لهاش
+
+284
+00:19:41,640 --> 00:19:46,140
+ارتباط، وبعرض الشريحة اللي عندي تحت الميكروسكوب،
+
+285
+00:19:46,140 --> 00:19:50,280
+وبدور على الومضات إذا كان موجود، العينة positive.
+
+286
+00:19:50,280 --> 00:19:54,060
+إذا مش موجود يعني الـ Antibody ما ارتبطش. الـ indirect
+
+287
+00:19:54,060 --> 00:19:57,380
+immunofluorescence staining, in which a secondary
+
+288
+00:19:57,380 --> 00:20:00,300
+antibody labelled with a fluorophore is used to
+
+289
+00:20:00,300 --> 00:20:06,560
+recognize the primary antibody. بيكون في عندي زي الـ
+
+290
+00:20:06,560 --> 00:20:10,890
+… إذا فاكرين الـ ELISA، لما كنا نعمل antibodies، الـ
+
+291
+00:20:10,890 --> 00:20:13,430
+primary antibody بيكون مش labelled، الـ secondary
+
+292
+00:20:13,430 --> 00:20:15,990
+antibody هو الـ labelled، وهنا نفس الفكرة، أنه في عندي
+
+293
+00:20:15,990 --> 00:20:18,270
+الـ secondary، الـ secondary antibody هو الـ labelled
+
+294
+00:20:18,270 --> 00:20:21,910
+بالـ fluorophore، واللي هو اللي بيرتبط بالـ primary
+
+295
+00:20:21,910 --> 00:20:31,910
+antibody وبيعطيني الومضات. نيجي
+
+296
+00:20:31,910 --> 00:20:35,110
+للنوع الأول، اللي هو الـ direct immunofluorescence.
+
+297
+00:20:35,110 --> 00:20:40,010
+في هذا النوع، طبعًا هي الـ procedure كتير بسيطة. بجيب
+
+298
+00:20:40,010 --> 00:20:42,430
+الـ tissue section اللي أنا بدور على الـ antigen
+
+299
+00:20:42,430 --> 00:20:48,490
+فيه أو الـ protein، بثبته على الـ slide، بعد هيك
+
+300
+00:20:48,490 --> 00:20:52,270
+fluorescein-labelled antibodies are layered over
+
+301
+00:20:52,270 --> 00:20:54,830
+it. بجيب الـ antibody اللي هو labelled بالـ
+
+302
+00:20:54,830 --> 00:20:59,470
+fluorescein وبحطه فوق على الشريحة هذه، طبعًا إذا
+
+303
+00:20:59,470 --> 00:21:02,890
+كان الـ antigen موجود، هيصير ارتباط، بعد هيك بعمل
+
+304
+00:21:02,890 --> 00:21:09,230
+washing عشان أشيل أي antibody ما ارتبطتش، بعد ذلك باخد
+
+305
+00:21:09,230 --> 00:21:11,890
+الشريحة وبحطها تحت الـ ultraviolet microscope
+
+306
+00:21:11,890 --> 00:21:17,210
+عشان أشوف اللون، إذا كان فيه ارتباط للـ antigen
+
+307
+00:21:17,210 --> 00:21:20,510
+بالـ antibody، هلاقي اللون الأخضر، إذا كانش فيه
+
+308
+00:21:20,510 --> 00:21:23,210
+ارتباط يعني العينة negative، اللون مش راح يكون
+
+309
+00:21:23,210 --> 00:21:26,610
+موجود. هذه بتستخدم في الـ direct detection of
+
+310
+00:21:26,610 --> 00:21:29,550
+pathogens or their antigens to show in
+
+311
+00:21:29,550 --> 00:21:33,090
+pathological samples. يعني لما بدور على pathogen أو
+
+312
+00:21:33,090 --> 00:21:37,840
+على أنتجين معيّن مباشرة في نسيج. الـ indirect
+
+313
+00:21:37,840 --> 00:21:40,620
+immunofluorescence عبارة عن double layer
+
+314
+00:21:40,620 --> 00:21:43,860
+technique. الطبقة الأولى بتكون هي الـ antigen، الـ
+
+315
+00:21:43,860 --> 00:21:47,420
+tissue اللي أنا بشتغل عليه، مرتبط فيه الـ primary
+
+316
+00:21:47,420 --> 00:21:51,420
+antibody، بعد هيك بضيف عليه الـ conjugated antibody،
+
+317
+00:21:51,420 --> 00:21:55,320
+اللي هو الـ secondary antibody، زي ما إحنا شايفين
+
+318
+00:21:55,320 --> 00:21:59,880
+هاي الـ indirect immunofluorescence. فيه عندي الـ
+
+319
+00:21:59,880 --> 00:22:02,580
+antigen، هاي primary reaction، بيرتبط الـ antigen
+
+320
+00:22:02,580 --> 00:22:05,380
+بالـ antibody. الـ secondary reaction، بجيب الـ
+
+321
+00:22:05,380 --> 00:22:08,120
+antibody، الـ labelled، ترتبط بالـ antibody الأولاني،
+
+322
+00:22:08,120 --> 00:22:11,480
+وطبعًا بعد هيك بقى يعني بعمل washing، وفي الخطوة هذه
+
+323
+00:22:11,480 --> 00:22:14,880
+لازم أعمل washing عشان أشيل أي existent antibody
+
+324
+00:22:14,880 --> 00:22:18,540
+ما ارتبطش، والخطوة اللي بعدها لازم أعمل washing عشان
+
+325
+00:22:18,540 --> 00:22:23,560
+أشيل أي برضه secondary antibody ما ارتبطش، وبعد هيك
+
+326
+00:22:23,560 --> 00:22:26,300
+بشوفها تحت الـ microscope. الشكل النهائي هيكون
+
+327
+00:22:26,300 --> 00:22:32,700
+antigen, unlabelled antibody, labelled antibody. عشان
+
+328
+00:22:32,700 --> 00:22:36,220
+زيّ الـ indirect immunofluorescence، أول حاجة
+
+329
+00:22:36,220 --> 00:22:39,420
+الإشارة بتكون واضحة، وومض قوي، لأن فيها
+
+330
+00:22:39,420 --> 00:22:44,020
+amplification effect، يعني هتعطيني إضاءة أقوى لـ
+
+331
+00:22:44,020 --> 00:22:49,000
+one molecule من البروتين. الشغل التاني المهم جدًا،
+
+332
+00:22:49,000 --> 00:22:54,420
+أنه أنا الـ indirect immunofluorescence لما بستخدم
+
+333
+00:22:54,420 --> 00:22:58,220
+الـ secondary antibody ما بيلزمني أجيب لكل فحص
+
+334
+00:22:58,220 --> 00:23:01,110
+secondary antibody. ليش؟ لأن الـ secondary antibody
+
+335
+00:23:01,110 --> 00:23:06,970
+ما هو specific لشيء معين، هو anti-IgG أو anti-
+
+336
+00:23:06,970 --> 00:23:11,010
+-immunoglobulin. فبالتالي إيش؟ مكان
+
+337
+00:23:11,010 --> 00:23:14,650
+الـ antibody الأول اللي أنا ضايفاه، هيرتبط الثاني
+
+338
+00:23:14,650 --> 00:23:18,490
+فيه، فبالتالي لو كان عندي one labelled, one antibody،
+
+339
+00:23:18,490 --> 00:23:22,070
+ممكن أعمل فيه مجموعة كبيرة من التحاليل. Requires
+
+340
+00:23:22,070 --> 00:23:25,110
+only one labelled antibody to identify many
+
+341
+00:23:25,110 --> 00:23:28,880
+proteins. The same labelled secondary antibody can be
+
+342
+00:23:28,880 --> 00:23:31,660
+used to bind to and light up many different proteins.
+
+343
+00:23:31,660 --> 00:23:34,460
+Preparation of labelled antibodies is difficult and
+
+344
+00:23:34,460 --> 00:23:39,480
+expensive. الأول كنت أنا مضطرة أحضّر لكل antigen
+
+345
+00:23:39,480 --> 00:23:43,520
+labelled antibody خاص فيه، لكن هنا تحضير الـ
+
+346
+00:23:43,520 --> 00:23:48,540
+labelled antibody هيكون مختصر، ليش؟ لأن كل الفحوصات
+
+347
+00:23:48,540 --> 00:23:51,860
+ممكن أعملها بـ labelled antibody واحد، والاختلاف بيكون
+
+348
+00:23:51,860 --> 00:23:54,680
+في الـ antibody الأول اللي هو مش labelled. تحضيره مش
+
+349
+00:23:54,680 --> 00:23:59,070
+هيغلبني. نيجي للمرض التاني اللي
+
+350
+00:23:59,070 --> 00:24:02,270
+بدنا نحكي عنه، اللي هو Systemic Lupus Erythematosus.
+
+351
+00:24:02,270 --> 00:24:06,790
+Systemic Lupus Erythematosus هو عبارة عن skin disease بيصير نتيجة وجود
+
+352
+00:24:06,790 --> 00:24:09,410
+الـ Anti-Nuclear Factor أو Anti-Nuclear
+
+353
+00:24:09,410 --> 00:24:13,470
+autoantibody. الـ Anti-Nuclear Factor هذا بتكون عند
+
+354
+00:24:13,470 --> 00:24:17,250
+المرضى اللي عندهم Systemic Lupus Erythematosus، وبصير يتفاعل مع
+
+355
+00:24:17,250 --> 00:24:21,130
+بقايا الأنوية اللي ناتجة من التكسير الطبيعي
+
+356
+00:24:21,130 --> 00:24:23,930
+للخلايا. طبعًا في عندنا خلايا باستمرار بتتجدّد في
+
+357
+00:24:23,930 --> 00:24:29,070
+الجسم، ففي وقتها هيصير لها تكسير. الـ products هذه
+
+358
+00:24:29,070 --> 00:24:32,050
+هتتفاعل مع الـ antinuclear factor، وتعمل عنده
+
+359
+00:24:32,050 --> 00:24:35,710
+immune complexes. الـ immune complexes هذه هتعمل
+
+360
+00:24:35,710 --> 00:24:40,030
+tissue damage. في هدول المرضى ممكن نلاقي حاجة
+
+361
+00:24:40,030 --> 00:24:43,810
+بنسمّيها الـ LE cell، هي عبارة عن mature neutrophil
+
+362
+00:24:43,810 --> 00:24:48,230
+بتظهر في الـ blood وفي الـ bone marrow. الـ LE cell
+
+363
+00:24:48,230 --> 00:24:53,760
+عبارة عن خلية بشوفها، أو بتعطيني positive result في
+
+364
+00:24:53,760 --> 00:24:58,480
+50% إلى 75% من الـ individuals اللي عندهم acute
+
+365
+00:24:58,480 --> 00:25:02,860
+Lupus Erythematosus. بالإضافة لإنه في بعض الحالات ممكن أشوف فيها
+
+366
+00:25:02,860 --> 00:25:06,520
+الـ LE cell، بس ما تكونش Lupus Erythematosus، زي حالات الـ
+
+367
+00:25:06,520 --> 00:25:09,980
+rheumatoid arthritis، الـ chronic hepatitis، الـ
+
+368
+00:25:09,980 --> 00:25:12,480
+acute hemolytic anemia، في الـ Hodgkin’s disease.
+
+369
+00:25:12,480 --> 00:25:17,660
+فبالتالي هي يعني مش فحص كتير حساس للـ Lupus Erythematosus. It may
+
+370
+00:25:17,660 --> 00:25:21,420
+also be positive in persons taking phenylbutazone
+
+371
+00:25:21,420 --> 00:25:25,680
+and hydralazine. هذه عبارة عن الـ drugs، لو أخدها
+
+372
+00:25:25,680 --> 00:25:29,860
+الإنسان أو الـ patient، ممكن ألاقي عنده الـ LE cells.
+
+373
+00:25:29,860 --> 00:25:36,760
+أو كيف بشوفها، الـ LE cells، كيف بتتكون أساسًا؟ بيكون في
+
+374
+00:25:36,760 --> 00:25:42,580
+عندي enucleus لخلية ما، قد تكون يعني طلعت من الخلية.
+
+375
+00:25:42,580 --> 00:25:47,300
+إحنا أساسًا في المختبر، في تكنيك خاص بنعمل فيه الـ
+
+376
+00:25:47,300 --> 00:25:51,060
+LE cells، يعني بنشجّع أو بنحفّز على تكوين الـ LE cells.
+
+377
+00:25:51,790 --> 00:25:55,290
+الفكرة بتعتمد على أنه إيش؟ بدي أطلع بعض الأنوية من
+
+378
+00:25:55,290 --> 00:25:58,890
+الخلايا، يعني أنا بهرس الخلايا، فبتطلع بعض الأنوية.
+
+379
+00:25:58,890 --> 00:26:03,650
+هلاقي الأنوية اللي طلعت، هتلاقي في الـ serum anti-
+
+380
+00:26:03,650 --> 00:26:06,490
+-nuclear factor. مش إحنا قلنا مرضى الـ
+
+381
+00:26:06,490 --> 00:26:09,890
+Systemic Lupus Erythematosus عندهم الـ Anti-nuclear factor؟ هيروح
+
+382
+00:26:09,890 --> 00:26:15,210
+الـ Anti-nuclear factor يعمل opsonization للنواة
+
+383
+00:26:15,210 --> 00:26:19,440
+هذه، هيرتبط فيها مين؟ اللي هتنتبه؟ الـ phagocyte، الـ
+
+384
+00:26:19,440 --> 00:26:22,160
+phagocyte لاقت في حاجة مرتبطة، بانتبه لدي، فهتيجي
+
+385
+00:26:22,160 --> 00:26:27,320
+تعمل لها phagocytosis. فأنا فعليًا هشوف خلية إما
+
+386
+00:26:27,320 --> 00:26:31,380
+neutrophil أو macrophage من الـ phagocytic cells
+
+387
+00:26:31,380 --> 00:26:35,440
+والـ phagocytized, degraded nuclear material from
+
+388
+00:26:35,440 --> 00:26:38,920
+another cell، هتروح عاملة phagocytosis لنواة من
+
+389
+00:26:38,920 --> 00:26:43,390
+خلية تانية. The engulfed nuclear material هتاخد صبغة
+
+390
+00:26:43,390 --> 00:26:48,630
+الـ hematoxylin بقوة، وتظهر في داخل الخلية، بما يسمّى
+
+391
+00:26:48,630 --> 00:26:52,350
+الـ LE body. زي ما أنتم شايفين، هذا الجسم هذا هو
+
+392
+00:26:52,350 --> 00:26:55,870
+كل الـ LE cell من إيش بتكون؟ من الخلية الأصلية،
+
+393
+00:26:55,870 --> 00:27:01,010
+نواة الخلية الأصلية هذه، نواتها مزاحة للأطراف، وفي
+
+394
+00:27:01,010 --> 00:27:05,990
+الوسط الـ engulfed nucleus بتكون فاتحة ومتجانسة،
+
+395
+00:27:05,990 --> 00:27:08,570
+لأنه صار لها phagocytosis، وصار لها lysis، والمرحلة اللي بعدها
+
+396
+00:27:08,570 --> 00:27:12,340
+كانت بتصير لها lysis. تمام. فهدي هي الـ LE cell.
+
+397
+00:27:12,340 --> 00:27:15,380
+Detection of LE cells is made through microscopic
+
+398
+00:27:15,380 --> 00:27:19,560
+examination. ممكن طبعًا أشوفها تحت الميكروسكوب. هذه
+
+399
+00:27:19,560 --> 00:27:23,560
+الطريقة كانت تستخدم قديمًا، ويعتمدوها بشكل أساسي
+
+400
+00:27:23,560 --> 00:27:26,380
+لتشخيص
+
+445
+00:30:29,450 --> 00:30:32,650
+مناعي، خدوا بالكم كلها عبارة عن أعراض مالهاش علاقة
+
+446
+00:30:32,650 --> 00:30:36,950
+بالفقوسات المناعية، طيب
+
+447
+00:30:36,950 --> 00:30:42,170
+من الخصائص الأخرى اللي وضعتها الـ Renal Involvement
+
+448
+00:30:42,170 --> 00:30:46,070
+Renal Involvement يعني إنه في مشاكل في الكلى ممكن
+
+449
+00:30:46,070 --> 00:30:49,070
+تشمل proteinuria plus three protein في الـ
+
+450
+00:30:49,070 --> 00:30:53,420
+dipstick أو وجود Cellular Cast زي الـ RBCs Cast و
+
+451
+00:30:53,420 --> 00:30:58,680
+الـ WBCs Cast طبعا يعني ممكن هذه بتتم تقييمها من
+
+452
+00:30:58,680 --> 00:31:02,640
+قبل الدكتور المعالج، الـ Neurological Disorder
+
+453
+00:31:02,640 --> 00:31:05,740
+يعني كتير منهم بتصير عندهم أغمات متكررة، بيصير
+
+454
+00:31:05,740 --> 00:31:10,760
+عندهم اكتئاب غير مبرر، مشاكل عصبية بتصاحب المرض، بس
+
+455
+00:31:10,760 --> 00:31:14,020
+لأن الـ Antibodies ممكن تأثر على الجهاز العصبي، مال
+
+456
+00:31:14,020 --> 00:31:17,780
+الراش اللي هي الـ Fixed Erythema اللي موجودة على
+
+457
+00:31:17,780 --> 00:31:21,180
+الخدين، على الوجه، على الوجنتين، وعلى الأنف، اللي هي
+
+458
+00:31:21,180 --> 00:31:26,400
+مخدة شكل Butterfly، ديسكويد راش، راش بهذا الشكل
+
+459
+00:31:26,400 --> 00:31:32,480
+بتكون دائرية، مرتفعة الحواف، مع عامل Scar في الوسط
+
+460
+00:31:32,900 --> 00:31:35,700
+الـ Criteria اللي إحنا حكينا فيها التسعة قبلها
+
+461
+00:31:35,700 --> 00:31:39,280
+كانت عبارة عن Clinical Criteria، نيجي الآن لآخر
+
+462
+00:31:39,280 --> 00:31:43,640
+اثنين اللي هم الـ Immunological Criteria، الأول وجود
+
+463
+00:31:43,640 --> 00:31:48,060
+Anti-Nuclear Antibodies بـ High Titer، يعني كل ما
+
+464
+00:31:48,060 --> 00:31:50,340
+كان الـ Titer أعلى بيكون الـ diagnosis more
+
+465
+00:31:50,340 --> 00:31:55,920
+specific، يكون الـ Titer فوق 160، شغلة ثانية وجود
+
+466
+00:31:55,920 --> 00:32:01,300
+يعني أنواع أخرى من الـ Antibodies المصاحبة لـ
+
+467
+00:32:01,300 --> 00:32:05,600
+Systemic Lupus، زي Double-Strand DNA، Anti-Double
+
+468
+00:32:05,600 --> 00:32:10,300
+-Strand DNA، Anti-Smith Antibodies، Anti
+
+469
+00:32:10,300 --> 00:32:12,860
+-phospholipids، زي الـ Anti-cardiolipin والـ Anti
+
+470
+00:32:12,860 --> 00:32:18,400
+-Lupus، هذه راح نقدر نحكي عنها بشكل مفصل أكثر، الـ
+
+471
+00:32:18,400 --> 00:32:21,340
+Antibodies الأخرى اللي بتوجد positive في Systemic
+
+472
+00:32:21,340 --> 00:32:25,460
+Lupus، طيب، هالـ 11 اللي حكينا فيهم عشان أشخص
+
+473
+00:32:25,460 --> 00:32:29,730
+Systemic Lupus، لازم يتوفر أربعة، الأربع هدول يكونوا
+
+474
+00:32:29,730 --> 00:32:34,770
+موزعين بين التسعة اللي حكيناهم قبل، اللي عبارة عن
+
+475
+00:32:34,770 --> 00:32:37,610
+الـ Clinical Criteria والتنتين هدول، يعني لازم
+
+476
+00:32:37,610 --> 00:32:42,650
+يتحقق على الأقل واحدة Clinical Criteria، واحدة من
+
+477
+00:32:42,650 --> 00:32:46,290
+الـ Immunological Criteria، وجود Antibody، يعني وجود
+
+478
+00:32:46,290 --> 00:32:51,350
+أربعة مع بعض من هذول، مع الـ Antibodies Negative
+
+479
+00:32:51,350 --> 00:32:55,660
+ما بتدل على شيء، بس يعني لازم يتواجدوا Clinical
+
+480
+00:32:55,660 --> 00:33:00,020
+criteria و Immunological criteria، على الأقل واحدة
+
+481
+00:33:00,020 --> 00:33:04,880
+من كل نوع، والمجموع يكون أربعة criteria عشان نشخص
+
+482
+00:33:04,880 --> 00:33:10,240
+Systemic Lupus عندي
+
+483
+00:33:10,240 --> 00:33:13,220
+هنا،  surgical tests اللي ممكن تعطيني positive في
+
+484
+00:33:13,220 --> 00:33:17,440
+Systemic Lupus، هناخدها يعني مش هيكون، مش هطلب
+
+485
+00:33:17,440 --> 00:33:20,740
+منكم تفاصيلها، بس يعني مش كل الأشياء هطلبها منكم
+
+486
+00:33:20,740 --> 00:33:26,090
+أول حاجة الـ ANA، الـ ANA يعتبر كـ Screening Test، الـ
+
+487
+00:33:26,090 --> 00:33:30,570
+Sensitivity بتاعته 95%، لكن إذا أعطاكي Positive بدون
+
+488
+00:33:30,570 --> 00:33:35,450
+Clinical Criteria، معنى الكلام إنه يعني لا يدل على
+
+489
+00:33:35,450 --> 00:33:38,510
+شيء، طبعا، لازم إذا أعطاكي Positive تدوري على
+
+490
+00:33:38,510 --> 00:33:41,450
+Clinical Criteria، إذا كانت موجودة، فبالتالي ممكن
+
+491
+00:33:41,450 --> 00:33:45,970
+تكون حالة Lupus، مافيش Clinical Criteria إذا مش
+
+492
+00:33:45,970 --> 00:33:49,830
+Lupus، طيب Anti-Double Strand DNA إله Specificity
+
+493
+00:33:49,830 --> 00:33:54,920
+عالية، بس الـ Sensitivity بتاعته بس 70%، وطبعا بتتغير
+
+494
+00:33:54,920 --> 00:33:59,380
+الـ level بتاعه حسب نشاط الـ disease، Anti-smooth
+
+495
+00:33:59,380 --> 00:34:05,800
+muscle، هذا أقل Specificity، بس 30%، يعني Specificity
+
+496
+00:34:05,800 --> 00:34:08,960
+بتاعته قليلة، والـ Sensitivity برضه قليلة، بس 30 إلى
+
+497
+00:34:08,960 --> 00:34:15,340
+40%، Anti-SSA أو Anti-Ribosomal،  Anti-RNP، Anti
+
+498
+00:34:15,340 --> 00:34:18,720
+-cardiolipin، Lupus، Anti-coagulant، هذه كلها
+
+499
+00:34:18,720 --> 00:34:22,670
+antibodies ممكن تكون positive في مرض اللوبس، الـ
+
+500
+00:34:22,670 --> 00:34:25,190
+Direct Coombs Test برضه بيكون Positive، Anti
+
+501
+00:34:25,190 --> 00:34:28,050
+-Histone، Antibodies Positive، بدون تفاصيل، مجرد
+
+502
+00:34:28,050 --> 00:34:31,170
+ذكر، يعني أنه تعرف أمتى الـ Antibodies اللي بتكون
+
+503
+00:34:31,170 --> 00:34:38,930
+موجودة في مرضى الـ Lupus، فحوصات أخرى يعني بتستخدم
+
+504
+00:34:38,930 --> 00:34:43,410
+في الـ diagnosis للـ Lupus، الـ CBC طبعا، الـ CBC
+
+505
+00:34:43,410 --> 00:34:47,190
+عشان نشوف الـ Leukopenia، Thrombocytopenia، ممكن نعمل
+
+506
+00:34:47,190 --> 00:34:49,930
+Creatinine, Serum Creatinine عشان نشوف الـ kidney function، Urine
+
+507
+00:34:49,930 --> 00:34:55,660
+analysis عشان نشوف وضع الكلى، طبعا ممكن كمان نشوف
+
+508
+00:34:55,660 --> 00:34:59,560
+الـ inflammatory markers اللي هي CRP و ESR، عادة
+
+509
+00:34:59,560 --> 00:35:03,700
+بيكونوا positive، مرتفعين، الـ complement components
+
+510
+00:35:03,700 --> 00:35:08,220
+ممكن تساعدني، لأن الـ C3 و C4 عادة بتنزل في الـ
+
+511
+00:35:08,220 --> 00:35:12,540
+patient اللي عندهم active Lupus، لأنه بيصير لها
+
+512
+00:35:12,540 --> 00:35:15,750
+consumption، بيصير لها استهلاك، لأن الـ Immune
+
+513
+00:35:15,750 --> 00:35:18,950
+Complexes بتتكون باستمرار، والـ Immune Complexes
+
+514
+00:35:18,950 --> 00:35:22,110
+بتسبب لها تنشيط للـ Complement، مما يؤدي لاستهلاك الـ
+
+515
+00:35:22,110 --> 00:35:24,990
+Complement Components، وإنه يسير في هذه الشخصية، نيجي
+
+516
+00:35:24,990 --> 00:35:29,790
+للـ Diagnosis الصحيح أو الدقيق، لقائمة الـ
+
+517
+00:35:29,790 --> 00:35:33,550
+Antibodies اللي بتتكون في الـ Systemic Lupus، نعرف
+
+518
+00:35:33,550 --> 00:35:37,910
+كيف بنشتغلها، هذه الـ Antibodies بتنشغل عن طريق الـ
+
+519
+00:35:37,910 --> 00:35:41,150
+Indirect Immunofluorescence Assay، يعني تعتبر الـ
+
+520
+00:35:41,150 --> 00:35:47,610
+Gold Standard للـ Diagnosis، طيب، بداية هنا طبعا
+
+521
+00:35:47,610 --> 00:35:51,930
+قائمة بأسماء الـ Antibodies، بداية الـ Antibodies
+
+522
+00:35:51,930 --> 00:35:54,830
+هذه، إذا أعطتني Negative، يعني الـ Antibody مش موجود
+
+523
+00:35:54,830 --> 00:35:59,490
+تمام؟ الـ Antibody لما بيتفاعل مع الـ Antigen اللي
+
+524
+00:35:59,490 --> 00:36:02,250
+أنا بحطه عشان أكشف من خلاله على الـ Antibody
+
+525
+00:36:02,250 --> 00:36:07,530
+هيعطيني Specific Fluorescence Pattern، يعني شكل
+
+526
+00:36:07,530 --> 00:36:11,710
+الـوميد، أو شكل الإضاءة هتكون مختلفة من Antibody
+
+527
+00:36:11,710 --> 00:36:16,690
+لـ Antibody، طب ليش فيه اختلاف؟ فيه اختلاف طبعا، هذا
+
+528
+00:36:16,690 --> 00:36:19,930
+الاختلاف أنا بشوفه تحت المايكروسكوب، بعد ما أحضر
+
+529
+00:36:19,930 --> 00:36:23,390
+الشريحة، بشوفها تحت المايكروسكوب، الاختلاف هذا جاء
+
+530
+00:36:23,390 --> 00:36:26,770
+من إيش؟ من توزيع الـ Antigen في داخل الخلية، فلقيت
+
+531
+00:36:26,770 --> 00:36:29,350
+أنا على سبيل المثال بدور على Antigen موجود في
+
+532
+00:36:29,350 --> 00:36:33,150
+النواة، أكيد الـ Antibody هيتفاعل مع الـ Antigen
+
+533
+00:36:33,150 --> 00:36:36,170
+الموجود في داخل النواة، وتكون الإضاءة داخل النواة
+
+534
+00:36:36,170 --> 00:36:38,910
+تمام؟ لو كان في الـ Cytoplasm، هتكون الإضاءة في
+
+535
+00:36:38,910 --> 00:36:44,380
+الـ Cytoplasm، كويس؟ طيب، النقطة الأخيرة هذه بتحكي أنه
+
+536
+00:36:44,380 --> 00:36:47,220
+أنا عشان أكشف عن الـ Antibodies هذه، أي واحد من الـ
+
+537
+00:36:47,220 --> 00:36:51,440
+Antibodies، لازم أكون مجهزة له Antigen مثبت على الـ
+
+538
+00:36:51,440 --> 00:36:56,640
+slide، الـ Antigen هذا بيحصل أنه بيتفاعل معاه، وبعد
+
+539
+00:36:56,640 --> 00:37:00,060
+هيك، أربطه بـ secondary antibody labelled، secondary
+
+540
+00:37:00,060 --> 00:37:05,220
+antibody، وأشوف الـ fluorescence، الشريحة التالية
+
+541
+00:37:05,220 --> 00:37:08,740
+بتحكي عن الـ substrate اللي أنا بدي استخدمها، أو الـ
+
+542
+00:37:08,740 --> 00:37:11,220
+Antigens اللي أنا بدي استخدمها للشغل
+
+543
+00:37:15,280 --> 00:37:19,620
+طيب، هنا قائمة بتقولك أمثلة على الـ Substrate
+
+544
+00:37:19,620 --> 00:37:23,040
+المستخدم، طبعا زي ما اتفقنا الـ Substrate هو عبارة
+
+545
+00:37:23,040 --> 00:37:26,680
+عن خلايا أو نسيج بيحتوي على الـ Antigen، وثبت على
+
+546
+00:37:26,680 --> 00:37:30,300
+slide، بضيف عليه العينة بتاعتي، إذا كان الـ Antibody
+
+547
+00:37:30,300 --> 00:37:33,800
+موجود، حيصير ارتباط، بعد ذلك بضيف الـ conjugated
+
+548
+00:37:33,800 --> 00:37:37,100
+antibody اللي هو معمول labelled، حيصير التفاعل
+
+549
+00:37:37,100 --> 00:37:41,810
+يعطيني إضاءة إذا كان موجود، مثلا لو أنا بدي أدور
+
+550
+00:37:41,810 --> 00:37:45,790
+على الـ Anti-Double-Strand DNA، في عندي نوع من
+
+551
+00:37:45,790 --> 00:37:48,750
+البدائيات بستخدمه، اللي هو Crithidia lucilliae
+
+552
+00:37:48,750 --> 00:37:55,370
+Substrate، الـ ANA ممكن أستخدم HEp-2 Cells، خلايا من
+
+553
+00:37:55,370 --> 00:37:59,430
+الكبد، أو Mouse Stomach Kidney Substrate، يعني يكون
+
+554
+00:37:59,430 --> 00:38:02,710
+الـ Substrate فيه خلايا من Mouse Stomach and
+
+555
+00:38:02,710 --> 00:38:07,860
+Kidney، الـ ASL, ASMA, AMA on Mouse Stomach Kidney
+
+556
+00:38:07,860 --> 00:38:12,600
+Substrate، Anti-LKM, Mouse Liver Stomach Kidney
+
+557
+00:38:12,600 --> 00:38:16,900
+Substrate، الـ ANCA, Neutrophil Substrate
+
+558
+00:38:16,900 --> 00:38:21,950
+Antithyroid Antibodies، لأن ثيرويد Antibodies
+
+559
+00:38:21,950 --> 00:38:25,490
+فبديجيب ثيرويد، بتتفاعل الـ Antigen مع الـ Antibody
+
+560
+00:38:25,490 --> 00:38:28,930
+في الـ indirect immunofluorescence، زي ما حكينا، كل
+
+561
+00:38:28,930 --> 00:38:33,510
+Antibody إله pattern معين في اللون يعني، أو في
+
+562
+00:38:33,510 --> 00:38:35,710
+الإضاءة اللي بتظهر، أو في الـ fluorescence اللي بيظهر
+
+563
+00:38:35,710 --> 00:38:39,570
+ممكن تبقى diffuse، homogeneous، يعني اللون متجانس
+
+564
+00:38:39,570 --> 00:38:45,290
+ممكن يبقى على شكل rim، يعني إضاءة محيطة بالنواة
+
+565
+00:38:45,290 --> 00:38:51,160
+speckled، منقط، nuclear، النواة، يعني جاية عند النوية
+
+566
+00:38:51,160 --> 00:38:55,440
+أو منطقة النوية هي اللي مضاءة، Centromeric، جاية في
+
+567
+00:38:55,440 --> 00:38:57,640
+منطقة الـ Centromere، راح ناخدها، لقيت أمثل عليها
+
+568
+00:38:57,640 --> 00:39:00,200
+طبعا كلها هذه عبارة عن Anti-nuclear antibodies
+
+569
+00:39:00,200 --> 00:39:04,080
+يعني Antibodies لأشياء موجودة في داخل النواة، نشوف
+
+570
+00:39:04,080 --> 00:39:11,920
+كيف شكل الـ reaction بيكون، Peripheral، أو rim، على شكل
+
+571
+00:39:11,920 --> 00:39:17,380
+خط رفيع حوالين النواة، زي الـ Anti-DNA، في حالات الـ
+
+572
+00:39:17,380 --> 00:39:20,520
+Systemic Lupus، Homogeneous، Diffused، زي الـ Anti
+
+573
+00:39:20,520 --> 00:39:26,240
+-DNA والـ Anti-Histone، Speckled، منقط، زي مجموعة
+
+574
+00:39:26,240 --> 00:39:31,880
+اللي هي الـ Anti-SM والـ Anti-RNP وAnti-Ro، يعني
+
+575
+00:39:31,880 --> 00:39:34,840
+مش كلهم تحفظوهم، هذا بحدد الـ combination اللي
+
+576
+00:39:34,840 --> 00:39:39,220
+مطلوب، Centromeric، بيكون حوالين الـ Centromere أو
+
+577
+00:39:39,220 --> 00:39:43,490
+بهذا الشكل، Anti-centromere in CREST syndrome، الـ
+
+578
+00:39:43,490 --> 00:39:47,690
+Nuclear بيكون عند الـ Nuclei، طيب
+
+579
+00:39:47,690 --> 00:39:50,430
+خلينا نشوف بعض النتائج، كيف بيكون شكلها تحت
+
+580
+00:39:50,430 --> 00:39:56,290
+المايكروسكوب، هذه مافيش أي Fluorescence أخضر، إذا النتيجة
+
+581
+00:39:56,290 --> 00:40:00,870
+Negative، نفس الفحص بس نتيجة Positive، زي ما أنتم
+
+582
+00:40:00,870 --> 00:40:04,890
+شايفين، اللون الأخضر هذا بيعني Positive، وشايفين أن
+
+583
+00:40:04,890 --> 00:40:09,110
+هذه الخلية والنواة كلها مضاءة بشكل Homogeneous، إذا
+
+584
+00:40:09,110 --> 00:40:11,190
+هذا الـ Diffused أو Homogeneous
+
+585
+00:40:15,670 --> 00:40:20,710
+Speckled، يعني إنه منقطة، مش homogenous، في مناطق
+
+586
+00:40:20,710 --> 00:40:28,730
+مضيئة ومناطق معتمة، وهذه برضه Speckled، هذه
+
+587
+00:40:28,730 --> 00:40:33,790
+Anti-nuclear اللي هي ضد النواة، الـ antibodies، زي ما
+
+588
+00:40:33,790 --> 00:40:39,870
+أنتم شايفين، منطقة الـ nucleolus هي المضاءة، هتشوفي
+
+589
+00:40:39,870 --> 00:40:43,550
+كل الـ field معتم إلا هذه المنطقة، هي هذه rim
+
+590
+00:40:43,550 --> 00:40:48,100
+pattern، على حوالين النواة، الـ rim جاي حوالين
+
+591
+00:40:48,100 --> 00:40:52,560
+النواة، نيجي
+
+592
+00:40:52,560 --> 00:40:58,100
+هنا Antibodies للـ Double Strand DNA، هنا المستخدم
+
+593
+00:40:58,100 --> 00:41:00,680
+السبسترات زي ما قلنا، اللي هي الـ Crithidia lucilliae
+
+594
+00:41:00,680 --> 00:41:05,160
+اللي هو نوع من البدائيات، هاي الـ positive result
+
+595
+00:41:05,160 --> 00:41:08,480
+هنا، هذه Negative Double Strand DNA، مافيش فيها
+
+596
+00:41:08,480 --> 00:41:11,060
+إضاءة، زي الصورة اللي قبلها، الصورة اللي قبلها كانت
+
+597
+00:41:11,060 --> 00:41:12,940
+فيها إضاءة، هذه مافيش فيها إضاءة
+
+598
+00:41:16,120 --> 00:41:20,220
+Anti-neutrophil-cytoplasmic antibodies، أكيد
+
+599
+00:41:20,220 --> 00:41:23,260
+Neutrophil cytoplasmic antibodies، إذا الـ
+
+600
+00:41:23,260 --> 00:41:25,500
+antibodies للسايتوبلازم، عشان هيك هتلاقي الإضاءة
+
+601
+00:41:25,500 --> 00:41:29,260
+في السايتوبلازم، مش في النواة، يسموها الـ ANCA، لاحظين
+
+602
+00:41:29,260 --> 00:41:33,880
+الإضاءة وين؟ في السايتوبلازم، عفوا،  معافى، معافى، هيك
+
+603
+00:41:33,880 --> 00:41:38,020
+بنكون خلصنا الـ diagnosis لـ autoimmune diseases
+
+604
+00:41:38,020 --> 00:41:42,140
+إحنا اختصرنا كتير من المحاضرة، إن شاء الله يارب
+
+605
+00:41:42,140 --> 00:41:44,220
+تكون الأمور واضحة، يعني
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/-rkSaY6nWL8_postprocess.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/-rkSaY6nWL8_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..480253c135c635be7ca9f0d9a9767fa16ba65cd1
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/-rkSaY6nWL8_postprocess.srt
@@ -0,0 +1,2420 @@
+1
+00:00:01,740 --> 00:00:06,180
+بسم الله الرحمن الرحيم موضوعنا إن شاء الله الـ
+
+2
+00:00:06,180 --> 00:00:10,420
+Autoimmune Diseases راح نحكي عنها نفذة مختصرة وراح
+
+3
+00:00:10,420 --> 00:00:12,740
+نحكي عن الـ Diagnosis طيبة لها بالنسبة للـ
+
+4
+00:00:12,740 --> 00:00:16,280
+Autoimmune Diseases الـ Autoimmune Diseases هي
+
+5
+00:00:16,280 --> 00:00:19,980
+عبارة عن مجموعة من الأمراض اللي بيصير فيها tissue
+
+6
+00:00:19,980 --> 00:00:24,540
+injury نتيجة اللي هي moral أو الـ cell-mediated
+
+7
+00:00:24,540 --> 00:00:28,020
+immune response اللي بيكون directed للـ self
+
+8
+00:00:28,020 --> 00:00:32,860
+-antigensعادةً الـ Immune System زي ما احنا عارفين
+
+9
+00:00:32,860 --> 00:00:35,580
+عنده القدرة إنه يميز الـ Self عن الـ Non-Self
+
+10
+00:00:35,580 --> 00:00:38,840
+Antigen لكن بالرغم من هذا، لدينا مجموعة كبيرة من
+
+11
+00:00:38,840 --> 00:00:41,740
+الـ Autoimmune Diseases اللي فيها الـ Immune
+
+12
+00:00:41,740 --> 00:00:47,820
+System بيعمل Attack لـ Self-Antigen أو Self-Cells
+
+13
+00:00:47,820 --> 00:00:51,440
+الـ Attack can be directed either against a very
+
+14
+00:00:51,440 --> 00:00:55,040
+specific tissue أو a large number of tissues يعني
+
+15
+00:00:55,040 --> 00:00:58,440
+المشكلة أو الـ Antibodies أو الـ Immune Response
+
+16
+00:00:58,440 --> 00:01:03,470
+اللي بيتكونقد يكون مخصص لنسيج معين أو لنوع معين من
+
+17
+00:01:03,470 --> 00:01:08,510
+الخلايا أو إنه بيهاجم أكتر من نوع من الانسجام once
+
+18
+00:01:08,510 --> 00:01:12,930
+started بمجرد بمجرد ما تبدأ ال autoimmune diseases
+
+19
+00:01:12,930 --> 00:01:16,850
+يعني صعب جدا أنها تبقى وضعت بعض التفسيرات اللي قد
+
+20
+00:01:16,850 --> 00:01:22,570
+تكون صحيحة وقد يكون فيها يعني في بعضها عدم وضوح
+
+21
+00:01:22,570 --> 00:01:28,470
+لحدوث ال autoimmune diseasesبداية فيه بقوله إنه
+
+22
+00:01:28,470 --> 00:01:32,650
+ممكن تتكون الـ autoimmune diseases نتيجة وجود بعض
+
+23
+00:01:32,650 --> 00:01:35,630
+الـ sequestered or hidden antigens يعني antigens
+
+24
+00:01:35,630 --> 00:01:40,150
+بتكون موجودة بالجسم لكن في مكان معزول يعني مافيش
+
+25
+00:01:40,150 --> 00:01:44,490
+contact ما بينها وبين جهاز المناعة على طول فممكن
+
+26
+00:01:44,490 --> 00:01:47,950
+في لحظة من اللحظات يشعر جهاز المناعة إنها دي
+
+27
+00:01:47,950 --> 00:01:51,010
+بالنسبة إليه foreign antigens زي الـ antigens
+
+28
+00:01:51,010 --> 00:01:55,290
+بتاعة الـ lens ال sperm antigen و الcyroglobin
+
+29
+00:01:55,290 --> 00:02:00,730
+تمام؟في عندي شغلة تانية تكون neo-antigens في الجسم
+
+30
+00:02:00,730 --> 00:02:04,850
+طيب من أيش ممكن تتكون الـ neo-antigens؟ الـ
+
+31
+00:02:04,850 --> 00:02:08,090
+antigens العادية اللي موجودة في الجسم أساساً ممكن
+
+32
+00:02:08,090 --> 00:02:12,730
+يحصل لها modification نتيجة التعرض لإشعاع أو
+
+33
+00:02:12,730 --> 00:02:16,050
+لعوامل فيزيائية معينة زي الإشعاع لبعض ال chemicals
+
+34
+00:02:16,050 --> 00:02:20,010
+زي ال drug أو لبعض ال microbes خاصة الـ
+
+35
+00:02:20,010 --> 00:02:23,610
+intracellular viruses ممكن يتغير الـ antigens
+
+36
+00:02:23,610 --> 00:02:27,540
+الموجودة على السلممبرانفبالتالي الجسم يتعرف عليها
+
+37
+00:02:27,540 --> 00:02:32,720
+إنها Foreign Antigens cessation of tolerance طبعا
+
+38
+00:02:32,720 --> 00:02:38,240
+إحنا عارفين إنه الجسم بيعمل tolerance مع الـself
+
+39
+00:02:38,240 --> 00:02:41,700
+-antigen فممكن إنه يحصل إنه هذه الـtolerance يصير
+
+40
+00:02:41,700 --> 00:02:45,700
+فيها خلال أكبر شغلة رابعة اللي هي وجود cross
+
+41
+00:02:45,700 --> 00:02:49,060
+-reacting antigens شو يعني cross-reacting
+
+42
+00:02:49,060 --> 00:02:53,110
+antigens؟ إنه فينا Foreign Antigensهذه الـ Foreign
+
+43
+00:02:53,110 --> 00:02:57,450
+Antigens شابهت بعض الـ Antigens الموجودة في الجسم
+
+44
+00:02:57,450 --> 00:03:01,550
+فلما الإنسان هيكون Antibodies الـ Antibodies هذه
+
+45
+00:03:01,550 --> 00:03:04,810
+هتعمل الـ Cross-reacting ما بين الـ Foreign
+
+46
+00:03:04,810 --> 00:03:08,710
+Antigen وما بين الـ Human أو الـ Self Antigen
+
+47
+00:03:08,710 --> 00:03:13,930
+فبينشأ عن هذا نوع من الـ Autoimmunity طبعاً هنا
+
+48
+00:03:13,930 --> 00:03:17,030
+بقولك Many species share organ specific antigens
+
+49
+00:03:17,030 --> 00:03:20,210
+يعني في عندنا كتير بعض ال species يعني أو species
+
+50
+00:03:20,210 --> 00:03:23,920
+متعددةممكن يكون فيه تشابه في بعض الـ organ
+
+51
+00:03:23,920 --> 00:03:28,860
+-antigens عندهم مثال زي الـ human brain و الـ
+
+52
+00:03:28,860 --> 00:03:32,880
+antigens of sheep brain هذه فيها تشابه طيب، شغلة
+
+53
+00:03:32,880 --> 00:03:35,680
+تانية الـ streptococcal unprotein and heart
+
+54
+00:03:35,680 --> 00:03:40,880
+muscles عشان هيك إذا اتعرض الإنسان لإصابة بالـ
+
+55
+00:03:40,880 --> 00:03:43,260
+streptococci فيه احتمال إن الـ antibody اللي
+
+56
+00:03:43,260 --> 00:03:47,280
+بيتكون يهاجم الـ heart muscle nephretogenic
+
+57
+00:03:47,280 --> 00:03:51,660
+strains of streptococci antigensتمام، ممكن الـ
+
+58
+00:03:51,660 --> 00:03:55,560
+Antigens بتاعتها هذه تتشابه مع الـ Renal Glomeruli
+
+59
+00:03:55,560 --> 00:03:59,780
+Epitopes أو Antigens على الخلايا، تمام؟ فبالتالي
+
+60
+00:03:59,780 --> 00:04:03,120
+لو اتكون Antibody ممكن يعمل cross-reacting ما
+
+61
+00:04:03,120 --> 00:04:08,760
+بينهم Loss of immune regulation هنا، يعني قلنا قبل
+
+62
+00:04:08,760 --> 00:04:12,800
+شوية أن في بعض الأحيان ممكن الـ Tolerance للـ Self
+
+63
+00:04:12,800 --> 00:04:17,560
+-antigen يصير لها cessation، تتوقف فهذه طبعا مشكلة
+
+64
+00:04:19,330 --> 00:04:24,430
+قد تكون بسبب over activity أو lowered activity لـ
+
+65
+00:04:24,430 --> 00:04:31,550
+T والـ B سلسل Classification
+
+66
+00:04:31,550 --> 00:04:34,430
+of autoimmune diseases الـ autoimmune diseases قد
+
+67
+00:04:34,430 --> 00:04:38,090
+تكون hemolytic يعني بتصيب لـ blood cells اتنين
+
+68
+00:04:38,090 --> 00:04:43,190
+localized تكون خاصة بنوع معين من الخلايا أو
+
+69
+00:04:43,190 --> 00:04:46,950
+systemic إنها بتصيب أكثر من organ في الجسم
+
+70
+00:04:50,570 --> 00:04:53,210
+النوع الأول اللي هي «Hemolytic Autoimmune
+
+71
+00:04:53,210 --> 00:04:58,970
+Diseases» اللي هو بيصير clinical disorder due to
+
+72
+00:04:58,970 --> 00:05:01,350
+destruction of blood components يعني ممكن تتكون
+
+73
+00:05:01,350 --> 00:05:04,990
+auto-antibodies للـRBCs للبلاي ثلاثة ليكوسايد
+
+74
+00:05:04,990 --> 00:05:07,870
+فبنتج عنه hemolytic anemia ليكوبينيا،
+
+75
+00:05:07,870 --> 00:05:10,550
+thrombocytopenia طيب نيجي للنوع التاني اللي هو
+
+76
+00:05:10,550 --> 00:05:14,790
+«Localized Autoimmune Diseases» طبعا هذه تسمى
+
+77
+00:05:14,790 --> 00:05:19,650
+organ specific autoimmune diseasesبتكون الـ
+
+78
+00:05:19,650 --> 00:05:23,630
+Antibodies directed لنوع معين من الخلايا موجود في
+
+79
+00:05:23,630 --> 00:05:27,590
+هذا الـ organ فبنتج عنه نوع من أنواع الـ
+
+80
+00:05:27,590 --> 00:05:34,010
+Autoimmune diseases طبعا زي من الأمثلة المشهورة
+
+81
+00:05:34,010 --> 00:05:37,950
+عليها اللي هي Thyroiditis Thyroiditis Antibodies
+
+82
+00:05:37,950 --> 00:05:42,410
+بتهاجم الثيرويد Multiple sclerosis Multiple
+
+83
+00:05:42,410 --> 00:05:46,150
+sclerosis عبارة عن مرض يسمونه تصلب اللويحي بالعربي
+
+84
+00:05:46,880 --> 00:05:51,020
+هنا بتتكون Antibodies لـ Myelin sheath اللي على
+
+85
+00:05:51,020 --> 00:05:53,760
+الخلايا العصبية بتعرفين أن Myelin sheath هذا
+
+86
+00:05:53,760 --> 00:05:58,800
+وظيفته أنه يسرع الإشارات العصبية فإذا اتكونت Auto
+
+87
+00:05:58,800 --> 00:06:03,780
+Antibodies لـ Myelin sheath هتصير الإشارات العصبية
+
+88
+00:06:03,780 --> 00:06:08,960
+بطيقة لأن Myelin sheath هنا هيفقد وظيفته و هيبدأ
+
+89
+00:06:08,960 --> 00:06:14,990
+يصير مشاكل يعني متعددة في الأعصابميساثينيا gravis
+
+90
+00:06:14,990 --> 00:06:20,810
+طبعا هنا المشكلة أنه بيصير attack لل nerve muscle
+
+91
+00:06:20,810 --> 00:06:25,110
+junction اللي هي المكان توصيل العصب بالعضلة
+
+92
+00:06:25,110 --> 00:06:29,490
+juvenile diabetes or type 1 diabetes اللي هي
+
+93
+00:06:29,490 --> 00:06:34,030
+بتتكون antibodies للإنسولين producing cells مثل
+
+94
+00:06:34,030 --> 00:06:35,870
+آخر اللي هو celiac disease
+
+95
+00:06:38,770 --> 00:06:41,790
+نيجي للـ Systemic Autoimmune Diseases الـ Systemic
+
+96
+00:06:41,790 --> 00:06:45,710
+Autoimmune Diseases عادة تسمى Non-Organ Specific
+
+97
+00:06:45,710 --> 00:06:48,930
+Autoimmune Diseases حيث إنه الـ Immune Complexes
+
+98
+00:06:48,930 --> 00:06:53,090
+تتجمع و بتتكون against different shock and cause
+
+99
+00:06:53,090 --> 00:06:57,010
+inflammation and damage طبعا هذه هتأثر على organs
+
+100
+00:06:57,010 --> 00:07:01,650
+كتير في الجسم من الأمثلة عليها Systemic Lobus بحيث
+
+101
+00:07:01,650 --> 00:07:05,430
+أنه الـ Antibody اللي بتكون Antinuclear يعني كل
+
+102
+00:07:05,430 --> 00:07:10,200
+مكان فيه نوة هيتكونله AntibodiesHarm Kidneys,
+
+103
+00:07:10,440 --> 00:07:15,880
+Heart, Brain, Lungs, Skin طيب من الأمثلة الأخرى
+
+104
+00:07:15,880 --> 00:07:18,600
+اللي هي «Rheumatoid Arthritis» «Rheumatoid
+
+105
+00:07:18,600 --> 00:07:23,200
+Arthritis» زي ما أخدنا إنه عبارة عن Anti-IgG
+
+106
+00:07:23,200 --> 00:07:26,720
+Antibodies طبعاً هذا هيضر المفاصل الـ Heart, Lung,
+
+107
+00:07:26,880 --> 00:07:31,080
+Nervous System «Rheumatic Fever» «Rheumatic Fever»
+
+108
+00:07:31,080 --> 00:07:35,180
+اللي هي اللي حكينا عنها بطلع الـ ASOT فيها
+
+109
+00:07:35,180 --> 00:07:38,860
+positiveبصير cross-reaction ما بين الـ Antibodies
+
+110
+00:07:38,860 --> 00:07:42,160
+Dystryptococcus و Auto-antibodies الـ Celiac
+
+111
+00:07:42,160 --> 00:07:46,720
+Disease عبارة عن مرض متعرف عليه باسم حساسية القمح
+
+112
+00:07:46,720 --> 00:07:51,260
+اللي اسمه تاني Celiac Sprew أو Gluten Sensitive
+
+113
+00:07:51,260 --> 00:07:54,900
+Enteropathy عبارة عن digestive autoimmune disorder
+
+114
+00:07:54,900 --> 00:07:58,340
+that result in damage to the lining of the small
+
+115
+00:07:58,340 --> 00:08:02,020
+intestine when foods with gluten are eatenيعني لما
+
+116
+00:08:02,020 --> 00:08:06,500
+الإنسان أو اللي عنده حساسية بياخد طعام بيحتوي على
+
+117
+00:08:06,500 --> 00:08:10,140
+الـ Gluten بيصير عنده تلف في الـ Villi اللي هي
+
+118
+00:08:10,140 --> 00:08:13,360
+الخمالات اللي بتمطص الغذاء الـ Gluten إيش هو؟
+
+119
+00:08:13,360 --> 00:08:16,080
+عبارة عن نوع من البروتينات موجودة في بعض الـ
+
+120
+00:08:16,080 --> 00:08:19,160
+Grains في الحبوب الـ damage to the intestine make
+
+121
+00:08:19,160 --> 00:08:22,220
+it hard for the body to absorb nutrients طبعا
+
+122
+00:08:22,220 --> 00:08:25,020
+تخيلوا معايا هذه الخمالات الطبيعية الـ Villi
+
+123
+00:08:25,020 --> 00:08:28,810
+الطبيعية وهي اللي صار فيها celiac diseaseهنا صار
+
+124
+00:08:28,810 --> 00:08:31,690
+فيها Atrophy فبالتالي مش هتقدر تنطص العناصر
+
+125
+00:08:31,690 --> 00:08:36,570
+الغذائية المهمة خاصة الدهون الـ Calcium، الـ Iron،
+
+126
+00:08:36,570 --> 00:08:38,670
+الـ Cholesterol إيش بسبب الـ Celiac Disease؟ الآن
+
+127
+00:08:38,670 --> 00:08:42,710
+لما الناس المصابة بهذا المرض تاكل طعام بيحتوي على
+
+128
+00:08:42,710 --> 00:08:46,410
+Gluten their immune system forms antibodies to
+
+129
+00:08:46,410 --> 00:08:49,850
+gluten هتكون antibodies لهذا البروتين هذا الـ
+
+130
+00:08:49,850 --> 00:08:53,570
+antibody will attack the intestinal lining هيهاجم
+
+131
+00:08:53,570 --> 00:08:57,600
+البطانة تحت الانتستنThis causes inflammation in
+
+132
+00:08:57,600 --> 00:09:00,800
+the intestine and damages the villi هيعمل
+
+133
+00:09:00,800 --> 00:09:04,980
+inflammation ويعمل damage للفيلي إيش هي الفيلي
+
+134
+00:09:04,980 --> 00:09:08,200
+طبعا عارفين هال hair like structures on the lining
+
+135
+00:09:08,200 --> 00:09:11,700
+of the small intestine ال nutrients from food are
+
+136
+00:09:11,700 --> 00:09:15,380
+normally absorbed by the villi طبعا إحنا عارفين أن
+
+137
+00:09:15,380 --> 00:09:18,340
+العناصر الغذائية بتتم إمتصاصها في الفيلي إذا
+
+138
+00:09:18,340 --> 00:09:21,960
+الفيلي صار فيها damage بالتالي هذا الشخص مش هيقدر
+
+139
+00:09:21,960 --> 00:09:26,300
+ينطص العناصر الغذائية وهيصير عنده malnutritionبغض
+
+140
+00:09:26,300 --> 00:09:30,300
+النظر قداش هو بياخد عناصر غذائية مافيش امتصاص إذا
+
+141
+00:09:30,300 --> 00:09:34,720
+هو مش هيستفيد منها Symptoms
+
+142
+00:09:34,720 --> 00:09:40,260
+of Celiac Disease طبعا الـ Symptoms يعني هتختلف من
+
+143
+00:09:40,260 --> 00:09:46,620
+واحد إلى واحد هتختلف حسب وجود الأعراض وحدتها بداية
+
+144
+00:09:46,620 --> 00:09:50,820
+Digestive Problems Abdominal Pluting انتفاخات،
+
+145
+00:09:50,820 --> 00:09:54,660
+pain، gas، diarrhea، bowel stool and weight loss
+
+146
+00:09:55,370 --> 00:10:01,270
+Severe skin rash called dermatitis herpetiformis
+
+147
+00:10:01,270 --> 00:10:04,570
+يعني يصير عندهم راش في الجلد Iron deficiency يعني
+
+148
+00:10:04,570 --> 00:10:07,930
+بعد ما ياخدوا الـ .. بعد ما ياخدوا الـ .. اللي هو
+
+149
+00:10:07,930 --> 00:10:10,710
+الـ grain اللي فيها الجلوتين هتصير عندهم هذه
+
+150
+00:10:10,710 --> 00:10:15,730
+الأعراض Iron deficiency anemia اللي هي نتيجة سوء
+
+151
+00:10:15,730 --> 00:10:19,450
+الامتصاص Muscle skeletal problems muscle cramps
+
+152
+00:10:19,450 --> 00:10:23,390
+joints and bones ليش؟ لأنه صار فيه نقص في العناصر
+
+153
+00:10:23,390 --> 00:10:27,060
+الغذائية نقص في الكالسيومنقص الأشياء اللي لازم لأ
+
+154
+00:10:27,060 --> 00:10:32,000
+الشغل الصحيح للعضلات و للعظام و للمفاصل الـ Growth
+
+155
+00:10:32,000 --> 00:10:35,160
+problems and failure to thrive بتلاقي في عندهم
+
+156
+00:10:35,160 --> 00:10:39,580
+صعوبة في النمو في الأطفال scissors tingling
+
+157
+00:10:39,580 --> 00:10:45,460
+sensation in the legs بتحس عندهم خدلان في الأطراف
+
+158
+00:10:45,460 --> 00:10:51,020
+في ال legs في الأجرين طبعا هذا بسبب نقص الكالسيوم
+
+159
+00:10:51,020 --> 00:10:57,230
+هيأثر على العضلات ال musclesObsess ulcers sore in
+
+160
+00:10:57,230 --> 00:11:01,570
+the mouth تكرار حدوث تقرحات في الفم missed
+
+161
+00:11:01,570 --> 00:11:04,470
+menstrual period بالنسبة لل female هتلاقي ال
+
+162
+00:11:04,470 --> 00:11:08,990
+menstrual period عندهم تقريبا مش منتظمة أو يعني
+
+163
+00:11:08,990 --> 00:11:15,370
+فترات طويلة لما بتصير health problems accompany
+
+164
+00:11:15,370 --> 00:11:17,950
+celiac disease celiac disease can leave persons
+
+165
+00:11:17,950 --> 00:11:21,750
+susceptible to other health problems يعني مضاعفات
+
+166
+00:11:21,930 --> 00:11:25,270
+زي الـ Osteoporosis Osteoporosis نتيجة سوء
+
+167
+00:11:25,270 --> 00:11:30,950
+الانتصاص حيصير في نوع من هشاشة العظام هشاشة العظام
+
+168
+00:11:30,950 --> 00:11:35,610
+هذه ليش؟ لأن هذا الشخص مايصير عنده انتصاص جيد لـ
+
+169
+00:11:35,610 --> 00:11:38,510
+Calcium أو لـ Vitamin دا المهمين جدا في بناء
+
+170
+00:11:38,510 --> 00:11:42,370
+العظام Miscarriage أو Infertility ممكن يصير إجهاد
+
+171
+00:11:42,370 --> 00:11:48,300
+أو عقوم Birth Defectsبرضه لأن الطفل خلال الحمل
+
+172
+00:11:48,300 --> 00:11:53,120
+بحتاج عناصر غذائية عشان يتكون بشكل جيد هدول في
+
+173
+00:11:53,120 --> 00:11:56,620
+عندهم malnutrition الستات الحوامل بيكون عندهم
+
+174
+00:11:56,620 --> 00:12:00,260
+malnutrition فبالتالي الطفل مش هتوصل لكميات
+
+175
+00:12:00,260 --> 00:12:03,880
+الغذائية المناسبة اللازمة لنموه فهيطلع عنده birth
+
+176
+00:12:03,880 --> 00:12:09,060
+defects خاصة neural tube defects neural tube
+
+177
+00:12:09,060 --> 00:12:12,450
+defects اللي عبداقة بكمية الفولك أسدعشان هيك
+
+178
+00:12:12,450 --> 00:12:15,410
+بيقولوا للستات الحوامل خدوا folic acid لأنه
+
+179
+00:12:15,410 --> 00:12:19,590
+بيقللوا كتير من التشوهات في الـ neural tube طبعا
+
+180
+00:12:19,590 --> 00:12:23,730
+في سوء امتصاص مش هيمطص الـfolic acid كويس فبيكون
+
+181
+00:12:23,730 --> 00:12:29,370
+الجنين عرضة لهيك أمراض Caesars Growth problems in
+
+182
+00:12:29,370 --> 00:12:31,530
+children because they don't absorb enough
+
+183
+00:12:31,530 --> 00:12:35,090
+nutrients Cancer of the intestine، very rare يعني
+
+184
+00:12:35,090 --> 00:12:39,030
+ممكن في بعض الحالات يصير cancer عندهم في الانتستان
+
+185
+00:12:40,690 --> 00:12:44,050
+نجي للـ diagnosis ال diagnosis بعتمد على شغلتان
+
+186
+00:12:44,050 --> 00:12:49,070
+بعتمد على وجود ال antibodies لأ للغلوتين لغلوتين
+
+187
+00:12:49,070 --> 00:12:55,490
+antibodies هذه يعني من النوع IgA عادة طبعا هذا
+
+188
+00:12:55,490 --> 00:12:59,850
+الفحص راح يكون صحيح إذا كان الشخص يعني فعليا بياخد
+
+189
+00:12:59,850 --> 00:13:03,830
+غلوتين مش متحمى عنه يعني لأنه لو متحمى وجيت أنا
+
+190
+00:13:03,830 --> 00:13:06,470
+عملت لغلوتين antibodies مش هلاقيها لأنه أصلا هو ما
+
+191
+00:13:06,470 --> 00:13:10,430
+بياخد غلوتين عشان تتكون له antibodiesالشغلة
+
+192
+00:13:10,430 --> 00:13:14,150
+التانية اللي هي مع ال lab test اللي هي small bowel
+
+193
+00:13:14,150 --> 00:13:17,470
+biopsy إننا نعمل biopsy من ال small bowel ونشوف
+
+194
+00:13:17,470 --> 00:13:21,090
+الأطرف اللي حاصلة في ال gut في ال villi الناس اللي
+
+195
+00:13:21,090 --> 00:13:24,250
+عندهم suspected dermatitis herpetiformis اللي هي
+
+196
+00:13:24,250 --> 00:13:27,930
+الحساسية أو الحكة skin biopsies will be taken of
+
+197
+00:13:27,930 --> 00:13:33,240
+the skin near the lesion ممكن ناخد skin biopsyالـ
+
+198
+00:13:33,240 --> 00:13:37,060
+Lab Diagnosis من الفحوصات اللي احنا ممكن نعملها في
+
+199
+00:13:37,060 --> 00:13:42,380
+المختبر عشان نشوف الـ Antibodies للـ Gluten أول
+
+200
+00:13:42,380 --> 00:13:45,700
+حاجة الـ Anti-Tissue Transglutaminase Antibody
+
+201
+00:13:45,700 --> 00:13:51,140
+Anti-TTG عادة زي ما قلنا ان هذه الـ Antibodies
+
+202
+00:13:51,140 --> 00:13:56,020
+بتنعمل IGA طبعا هذا Antibody لإنزيم اللي هو Tissue
+
+203
+00:13:56,020 --> 00:13:59,970
+Transglutaminaseالأنزيم اللي يسبب فيه الـ cross
+
+204
+00:13:59,970 --> 00:14:02,870
+-linking ‏of certain proteins يعني هو بيعمل cross
+
+205
+00:14:02,870 --> 00:14:10,170
+-linking للبروتينات عادة يعني بيكون في ال ‏celiac
+
+206
+00:14:10,170 --> 00:14:12,630
+disease في الـ celiac disease بتكون antibodies
+
+207
+00:14:12,630 --> 00:14:18,310
+لهذا الانزيم من النوع IGA طبعا IGA is the most
+
+208
+00:14:18,310 --> 00:14:20,950
+‏sensitive and specific blood test ‏for celiac
+
+209
+00:14:20,950 --> 00:14:25,630
+disease هذا اللي هو الانزيم خاصة ال IGA أفضل واحد
+
+210
+00:14:25,630 --> 00:14:31,190
+أحيانا بنضطرنعمل الـ IgG class من الـ Anti-TTG لما
+
+211
+00:14:31,190 --> 00:14:36,010
+يكون في مشكلة في IgA عند هذا الشخص يعني بس الخيار
+
+212
+00:14:36,010 --> 00:14:39,210
+الأول اللي هو هذا الإنزيم النوع IgG أفضل واحد
+
+213
+00:14:39,210 --> 00:14:43,790
+الخيار اللي بعده دي Aminated Glycine Peptidase نفس
+
+214
+00:14:43,790 --> 00:14:48,150
+الشيء ممكن أعمله IgA و لو في عند الشخص هذا مشكلة
+
+215
+00:14:48,150 --> 00:14:52,490
+أو deficiency في ال IgA ممكن أعمل نفس ال antibody
+
+216
+00:14:52,490 --> 00:14:55,710
+هذا IgG
+
+217
+00:14:59,130 --> 00:15:03,070
+Other tests less commonly performed include يعني
+
+218
+00:15:03,070 --> 00:15:06,490
+هذا الفحص أقل شيوعا اللي هو Anti-endometrial
+
+219
+00:15:06,490 --> 00:15:11,750
+antibodies اللي هو EMA IGA class detect antibodies
+
+220
+00:15:11,750 --> 00:15:14,350
+to endometrium إيش هو ال endometrium؟ ال
+
+221
+00:15:14,350 --> 00:15:18,390
+endometrium عبارة عن غشاء رقيق يحيط بالعضلات بال
+
+222
+00:15:18,390 --> 00:15:24,720
+muscle ل fibersعادة في الـ Celiac Disease بنلاحظ
+
+223
+00:15:24,720 --> 00:15:29,120
+وتكون Antibodies لهذا النوع من الـ لهذا الغشاء
+
+224
+00:15:29,120 --> 00:15:32,960
+اللي هو الـ Endometrium تمام؟ في عندي شغلة تانية
+
+225
+00:15:32,960 --> 00:15:38,220
+اللي هو Anti-reticulin antibody ARA not as
+
+226
+00:15:38,220 --> 00:15:41,200
+specific or sensitive as the other autoantibodies
+
+227
+00:15:41,200 --> 00:15:45,260
+احنا لحد فترة قريبة كنا نعمل الـ Anti-endometrial
+
+228
+00:15:45,260 --> 00:15:49,600
+antibody بس صحيح ال kit بتاعه من عنا خلصإن شاء
+
+229
+00:15:49,600 --> 00:15:53,320
+الله يعني نتأمل أنه يجي لأن هو بنعمل fluorescence
+
+230
+00:15:53,320 --> 00:15:58,480
+وحتى لو ماعملنهاش فيه عنا شرايح محفوظة إن شاء الله
+
+231
+00:15:58,480 --> 00:16:07,620
+بتكون ضايلة كويسة بنورجيكم النتائج تبعة الفحص طيب
+
+232
+00:16:07,620 --> 00:16:11,960
+diagnosis of autoimmune diseases بشكل عام أول حاجة
+
+233
+00:16:11,960 --> 00:16:15,820
+diagnosis of clinical symptomsconfirmed by
+
+234
+00:16:15,820 --> 00:16:18,820
+detecting the autoantibodies in the serum of the
+
+235
+00:16:18,820 --> 00:16:22,100
+patient autoantibodies are demonstrated by
+
+236
+00:16:22,100 --> 00:16:24,860
+immunofluorescence antibody test hemagglutination
+
+237
+00:16:24,860 --> 00:16:27,780
+complement fixation immunodiffusion
+
+238
+00:16:27,780 --> 00:16:30,700
+radioimmunoassay لذن أنا بدي أدور على ال
+
+239
+00:16:30,700 --> 00:16:33,920
+autoantibodies بأحد التقنيات هذه كل التقنيات هذه
+
+240
+00:16:33,920 --> 00:16:38,220
+تقريبا حكينا عنها بعد ال immunofluorescence و ال
+
+241
+00:16:38,220 --> 00:16:40,640
+complement fixation جيه ان شاء الله هنحكي عنهم
+
+242
+00:16:40,640 --> 00:16:47,940
+لقدامنيجي لتقنية الـ Immunofluorescence Assay الـ
+
+243
+00:16:47,940 --> 00:16:51,640
+Immunofluorescence Technique عبارة عن تقنية تسمح
+
+244
+00:16:51,640 --> 00:16:56,600
+لي أني أشوف بروتين أو أنتجن موجود في الـ tissue
+
+245
+00:16:56,600 --> 00:17:01,280
+section يعني بيكون عندي tissue section ال tissue
+
+246
+00:17:01,280 --> 00:17:04,680
+section هذا أنا بدور فيه على بروتين أو على أنتجن
+
+247
+00:17:04,680 --> 00:17:08,660
+معين عن طريق أني أنا بكون جاي باله Antibody
+
+248
+00:17:08,660 --> 00:17:13,120
+Antibody labelled بـH بالفلوريسينالـ Fluorescein
+
+249
+00:17:13,120 --> 00:17:18,660
+Isothiocyanate هذه عبارة عن صبغة تتميز بأنه أنا
+
+250
+00:17:18,660 --> 00:17:22,820
+لما بسقط عليها الـ Ultraviolet بتعطيني وميد أخضر
+
+251
+00:17:22,820 --> 00:17:27,100
+أو لون أخضر الـ Specific Antibodies are labelled
+
+252
+00:17:27,100 --> 00:17:33,580
+with a compound اللي هو Fluorescein Isothiocyanate
+
+253
+00:17:33,580 --> 00:17:37,680
+that makes them glow an ugly green colour when
+
+254
+00:17:37,680 --> 00:17:40,640
+observed microscopically under ultraviolet
+
+255
+00:17:40,640 --> 00:17:44,620
+microscopeإذن أنا بدور على Antigen أو Antibody فيه
+
+256
+00:17:44,620 --> 00:17:46,760
+الـ Fluorescence لما أجيبله Antibody ليه؟ فالـ
+
+257
+00:17:46,760 --> 00:17:51,480
+Fluorescence هي خاصية لبعض الـ Molecules اللي
+
+258
+00:17:51,480 --> 00:17:58,320
+بتمتص ضوء بطول موجي معين الآن لما بتمتص هذا الضوء
+
+259
+00:17:58,320 --> 00:18:03,180
+بيصير Excitation للإلكترون إلى مستويات الطاقة أعلى
+
+260
+00:18:03,180 --> 00:18:07,480
+لقيت لما بترجع الإلكترون إلى مستويات الطاقة الأولى
+
+261
+00:18:07,850 --> 00:18:12,790
+بتفقد طاقتها على شكل ضوء بطول موجي أعلى من اللي تم
+
+262
+00:18:12,790 --> 00:18:18,110
+امتصاصه فبتعطيني تقلق أو وميده is the property of
+
+263
+00:18:18,110 --> 00:18:22,930
+certain molecules of fluorophores to absorb light
+
+264
+00:18:22,930 --> 00:18:25,890
+at one wavelength and emit light to longer
+
+265
+00:18:25,890 --> 00:18:29,110
+wavelengths emission wavelengths when it is
+
+266
+00:18:29,110 --> 00:18:32,470
+illuminated by light of different wavelengths
+
+267
+00:18:32,470 --> 00:18:36,950
+excitation wavelengthsيعني أنا بحط ببعرضها ل light
+
+268
+00:18:36,950 --> 00:18:40,410
+ال light هدى يعمل لها excitation the incident
+
+269
+00:18:40,410 --> 00:18:44,390
+light excites the molecules to a higher levels of
+
+270
+00:18:44,390 --> 00:18:47,270
+vibration energy يعني بتعمل لها excitation
+
+271
+00:18:47,270 --> 00:18:51,770
+لمستويات طاقة أعلى as the molecules return to the
+
+272
+00:18:51,770 --> 00:18:55,710
+ground state the excitedFluorophores emitted a
+
+273
+00:18:55,710 --> 00:18:58,710
+photon fluorescence emission يعني لما بترجع
+
+274
+00:18:58,710 --> 00:19:02,310
+بتعطينا دائما هذا ال fluorescence microscope موجود
+
+275
+00:19:02,310 --> 00:19:06,670
+عندنا وان شاء الله ربنا يعني بيسر الأمور و بنقدر
+
+276
+00:19:06,670 --> 00:19:10,370
+ان نشوف على الأقل العينات الموجودة الجاهزة عندنا
+
+277
+00:19:10,370 --> 00:19:16,050
+على ال fluorescence microscope types
+
+278
+00:19:16,050 --> 00:19:20,550
+of immunofluorescence أول حاجة في عند direct
+
+279
+00:19:20,550 --> 00:19:24,380
+immunofluorescenceStaining in which the primary
+
+280
+00:19:24,380 --> 00:19:27,320
+antibody is labeled with fluorescence type يعني
+
+281
+00:19:27,320 --> 00:19:32,380
+فيه indirect و indirect ال direct بعمل labeling لل
+
+282
+00:19:32,380 --> 00:19:37,220
+antibody اللي بده يرتبط مباشرة بالانتجان وبعد هيك
+
+283
+00:19:37,220 --> 00:19:41,640
+طبعا بعمل washing بشيل أي antibody ماصار لهاش
+
+284
+00:19:41,640 --> 00:19:46,140
+ارتباطوبعرض الشريحة اللي عندي تحت الميكروسكوب
+
+285
+00:19:46,140 --> 00:19:50,280
+وبدور على الواميد إذا كان موجود العينة positive
+
+286
+00:19:50,280 --> 00:19:54,060
+إذا مش موجود يعني الـ Antibody مرتبط الـ indirect
+
+287
+00:19:54,060 --> 00:19:57,380
+immunofluorescence staining in which a secondary
+
+288
+00:19:57,380 --> 00:20:00,300
+antibody label with fluorochrome is used to
+
+289
+00:20:00,300 --> 00:20:06,560
+recognize a primary antibody بيكون في عندي زي ال
+
+290
+00:20:06,560 --> 00:20:10,890
+.. إذا فاكرين الـ ELISA لما كنتتو antibodies ال
+
+291
+00:20:10,890 --> 00:20:13,430
+primary antibody بكونش labelled ال secondary
+
+292
+00:20:13,430 --> 00:20:15,990
+antibody هو ال labelled وهنا نفس الفكرة أنه في عند
+
+293
+00:20:15,990 --> 00:20:18,270
+ال secondary ال secondary antibody هو ال labelled
+
+294
+00:20:18,270 --> 00:20:21,910
+بال fluorochrome و اللي هو اللي بيرتبط بال primary
+
+295
+00:20:21,910 --> 00:20:31,910
+antibody وبيعطيني ال وميد نيجي
+
+296
+00:20:31,910 --> 00:20:35,110
+للنوع الأول اللي هو ال direct immunofluorescence
+
+297
+00:20:35,110 --> 00:20:40,010
+في هذا النوع طبعا هي ال procedure كتير بسيطةبجيب
+
+298
+00:20:40,010 --> 00:20:42,430
+الـ tissue section اللي أنا بدور على الـ antigen
+
+299
+00:20:42,430 --> 00:20:48,490
+فيه أو الـ protein بثبته على الـ slide بعد هيك
+
+300
+00:20:48,490 --> 00:20:52,270
+fluorescein labelled antibodies are layered over
+
+301
+00:20:52,270 --> 00:20:54,830
+it بجيب الـ antibody اللي هو labelled بالـ
+
+302
+00:20:54,830 --> 00:20:59,470
+fluorescein و بحطه فاء على الشريحة هذه طبعا إذا
+
+303
+00:20:59,470 --> 00:21:02,890
+كان الـ antigen موجود هيصير ارتباط بعد هيك بعمل
+
+304
+00:21:02,890 --> 00:21:09,230
+washing عشان أشيل أي antibody مارتبطشبعد ذلك باخد
+
+305
+00:21:09,230 --> 00:21:11,890
+الشريحة و بحطها تحت الـ Ultraviolet Microscope
+
+306
+00:21:11,890 --> 00:21:17,210
+عشان أشوف اللون إذا كان فيه ارتباط للـ Antigen
+
+307
+00:21:17,210 --> 00:21:20,510
+بالـ Antibody حلاء اللون الأخضر إذا كانش فيه
+
+308
+00:21:20,510 --> 00:21:23,210
+ارتباط يعني العينة negative اللون مش راح يكون
+
+309
+00:21:23,210 --> 00:21:26,610
+موجود هذه بتستخدم في الـ Direct detection of
+
+310
+00:21:26,610 --> 00:21:29,550
+pathogens or their antigens to show or in
+
+311
+00:21:29,550 --> 00:21:33,090
+pathological samples يعني لما بدور على pathogen أو
+
+312
+00:21:33,090 --> 00:21:37,840
+على أنتجين معين مباشرة في نسيجالـ Indirect
+
+313
+00:21:37,840 --> 00:21:40,620
+Immunofluorescence عبارة عن Double Layers
+
+314
+00:21:40,620 --> 00:21:43,860
+Technique الطبقة الأولى بتكون هو الـ Antigen الـ
+
+315
+00:21:43,860 --> 00:21:47,420
+Tissue اللي أنا بشتغل عليه مرتبط فيه الـ Primary
+
+316
+00:21:47,420 --> 00:21:51,420
+Antibody بعد هيك بضيف عليه الـ Conjugated Antibody
+
+317
+00:21:51,420 --> 00:21:55,320
+اللي هو الـ Secondary Antibody زي ما إحنا شايفين
+
+318
+00:21:55,320 --> 00:21:59,880
+هاي الـ Indirect Immunofluorescence في عند الـ
+
+319
+00:21:59,880 --> 00:22:02,580
+Antigen هاي Primary Reaction برتبط الـ Antigen
+
+320
+00:22:02,580 --> 00:22:05,380
+بالـ Antibodyالـ Secondary Reaction بجيب الـ
+
+321
+00:22:05,380 --> 00:22:08,120
+Antibody الـ Label ترتبط بالـ Antibody الأولاني
+
+322
+00:22:08,120 --> 00:22:11,480
+وطبعا بعد هيك بقى يعني بعمل Washing وفي الخطوة هذه
+
+323
+00:22:11,480 --> 00:22:14,880
+لازم أعمل Washing عشان أشيل أي Exist Antibody
+
+324
+00:22:14,880 --> 00:22:18,540
+مرتبطش و الخطوة اللي بعدها لازم أعمل Washing عشان
+
+325
+00:22:18,540 --> 00:22:23,560
+أشيل أي برضه Secondary Antibody مرتبط و بعد هيك
+
+326
+00:22:23,560 --> 00:22:26,300
+بشوفها تحت ال Microscope الشكل النهائي هيكون
+
+327
+00:22:26,300 --> 00:22:32,700
+Antigen Unlabeled Antibody Labeled Antibodyعشما
+
+328
+00:22:32,700 --> 00:22:36,220
+زاية الـ indirect immunofluorescence أول حاجة
+
+329
+00:22:36,220 --> 00:22:39,420
+الإشارة بتكون واضحة و وميد قوي لأن فيها
+
+330
+00:22:39,420 --> 00:22:44,020
+amplification effect يعني هتعطيني إضاءة أقوى ل الـ
+
+331
+00:22:44,020 --> 00:22:49,000
+one molecule من البروتين الشغل التاني المهم جدا
+
+332
+00:22:49,000 --> 00:22:54,420
+أنه أنا ال indirect immunofluorescence لما بستخدم
+
+333
+00:22:54,420 --> 00:22:58,220
+ال secondary antibody مابيلزمني أجيب لكل فحص
+
+334
+00:22:58,220 --> 00:23:01,110
+secondary antibodyليش؟ لأن الـ Secondary Antibody
+
+335
+00:23:01,110 --> 00:23:06,970
+ما هوش specific لشيء معين هو Anti-IgG أو Anti
+
+336
+00:23:06,970 --> 00:23:11,010
+-Antibody Anti-Immunoglobulin فبالتالي إيش مكان
+
+337
+00:23:11,010 --> 00:23:14,650
+الـ Antibody الأول اللي أنا ضايفاه هيرتبط التاني
+
+338
+00:23:14,650 --> 00:23:18,490
+فيه فبالتالي لو كان عندي One Label، One Antibody
+
+339
+00:23:18,490 --> 00:23:22,070
+ممكن أعمل فيه مجموعة كبيرة من التحصات Requires
+
+340
+00:23:22,070 --> 00:23:25,110
+only one labeled antibody to identify many
+
+341
+00:23:25,110 --> 00:23:28,880
+proteinsSame labelled secondary antibody can be
+
+342
+00:23:28,880 --> 00:23:31,660
+used to bind to light up many different proteins
+
+343
+00:23:31,660 --> 00:23:34,460
+preparation of labelled antibody is difficult and
+
+344
+00:23:34,460 --> 00:23:39,480
+expensive الأول كنت أنا مضطرة أحضر لكل أنتجن
+
+345
+00:23:39,480 --> 00:23:43,520
+labelled antibody خاص فيه لكن هنا تحضير ال
+
+346
+00:23:43,520 --> 00:23:48,540
+labelled antibody هيكون مختصر ليش؟ لأن كل الفحوصات
+
+347
+00:23:48,540 --> 00:23:51,860
+ممكن أعملهم labelled antibody واحد والاختلاف بيكون
+
+348
+00:23:51,860 --> 00:23:54,680
+في ال antibody الأول اللي هو مش labelled تحضيره مش
+
+349
+00:23:54,680 --> 00:23:59,070
+هيغلبني زيتحضر الـ Level أعلى أو المرض التاني اللي
+
+350
+00:23:59,070 --> 00:24:02,270
+بدنا نحكي عنه اللي هو Systemic Lobes Systemic
+
+351
+00:24:02,270 --> 00:24:06,790
+Lobes هو عبارة عن Skin Disease بيصير نتيجة وجود
+
+352
+00:24:06,790 --> 00:24:09,410
+الـ Anti-Nuclear Factor أو Anti-Nuclear
+
+353
+00:24:09,410 --> 00:24:13,470
+Autoantibody الـ Anti-Nuclear Factor هذا بتكون عند
+
+354
+00:24:13,470 --> 00:24:17,250
+المرضى تعون الـ Systemic Lobes وبصير يتفاعل مع
+
+355
+00:24:17,250 --> 00:24:21,130
+بقايا الأنوية اللي ناتجة من التكسير الطبيعي
+
+356
+00:24:21,130 --> 00:24:23,930
+للخلايا طبعا في عندنا خلايا باستمرار تتجدد في
+
+357
+00:24:23,930 --> 00:24:29,070
+الجسمفانه وقتها هيصير لها تكسير الـ Product هذه
+
+358
+00:24:29,070 --> 00:24:32,050
+هتتفاعل مع الـ Antinuclear factor وتعمل عنده
+
+359
+00:24:32,050 --> 00:24:35,710
+immune complexes الimmune complexes هذه هتعمل
+
+360
+00:24:35,710 --> 00:24:40,030
+tissue damage في هدول المرضى ممكن نلاقي حاجة
+
+361
+00:24:40,030 --> 00:24:43,810
+بنسميها الـ A cell هي عبارة عن mature neutrophil
+
+362
+00:24:43,810 --> 00:24:48,230
+بتظهر في ال blood وفي ال bone marrow الـ A cell
+
+363
+00:24:48,230 --> 00:24:53,760
+عبارة عن خلية بشوفها أو بتعطيني positive resultفي
+
+364
+00:24:53,760 --> 00:24:58,480
+50 إلى 75% من الـ individuals اللي عندهم acute
+
+365
+00:24:58,480 --> 00:25:02,860
+lobus بالاضافة لإنه في بعض الحالات ممكن أشوف فيها
+
+366
+00:25:02,860 --> 00:25:06,520
+الـ E cell بس ما تكونش lobus زي حالات الـ
+
+367
+00:25:06,520 --> 00:25:09,980
+rheumatoid arthritis الـ chronic hepatitis الـ
+
+368
+00:25:09,980 --> 00:25:12,480
+acute hemolytic anemia في الـ Hodgkin disease
+
+369
+00:25:12,480 --> 00:25:17,660
+فبالتالي هي يعني مش فحص كتير حساس للـ lobus it may
+
+370
+00:25:17,660 --> 00:25:21,420
+also be positive in persons taking phenylbutazone
+
+371
+00:25:21,420 --> 00:25:25,680
+and hydrazolineهذه عبارة عن الـ Drugs لو أخدها
+
+372
+00:25:25,680 --> 00:25:29,860
+الإنسان أو الـ Patient ممكن ألاقي عنده الـ LES-L
+
+373
+00:25:29,860 --> 00:25:36,760
+أو كيف بشوفها الـ LES-L كيف بتتكون أساساً بيكون في
+
+374
+00:25:36,760 --> 00:25:42,580
+عندي Enucleus لخلية ما قد تكون يعني طلعت من الخلية
+
+375
+00:25:42,580 --> 00:25:47,300
+إحنا أساساً في المختبر في تكنيك خاص بنعمل فيه الـ
+
+376
+00:25:47,300 --> 00:25:51,060
+LES-L يعني بنشجع أو بنحفز على تكوين الـ LES-L
+
+377
+00:25:51,790 --> 00:25:55,290
+الفكرة بتعتمد على إنه إيش بدي أطلع بعض الأنوية من
+
+378
+00:25:55,290 --> 00:25:58,890
+الخلايا يعني أنا بهرس الخلايا فبتطلع بعض الأنوية
+
+379
+00:25:58,890 --> 00:26:03,650
+هلاقيت الأنوية اللي طلعت هتلاقي في الـ Serum Anti
+
+380
+00:26:03,650 --> 00:26:06,490
+-nuclear factor مش احنا قولنا الـ LE مرضى الـ
+
+381
+00:26:06,490 --> 00:26:09,890
+Systemic lobus عندهم الـ Anti-nuclear factor هيروح
+
+382
+00:26:09,890 --> 00:26:15,210
+الـ Anti-nuclear factor يعمل optionization للنواة
+
+383
+00:26:15,210 --> 00:26:19,440
+هذه هيرتبط فيها مين اللي هتنتبه؟الـ Phagocyte الـ
+
+384
+00:26:19,440 --> 00:26:22,160
+Phagocyte لقت في حاجة مرتبطة بانتباه دي فهتيجي
+
+385
+00:26:22,160 --> 00:26:27,320
+تعملها Phagocytosis فأنا فعليا هشوف خلية إما
+
+386
+00:26:27,320 --> 00:26:31,380
+Neutrophil أو Macrophage من الـ Phagocytic cells
+
+387
+00:26:31,380 --> 00:26:35,440
+والـ Phagocytized degraded nuclear material from
+
+388
+00:26:35,440 --> 00:26:38,920
+another cell هتروح عاملة Phagocytosis لنواة من
+
+389
+00:26:38,920 --> 00:26:43,390
+خلية تانيةThe engulfed nuclear material هتاخد صبغة
+
+390
+00:26:43,390 --> 00:26:48,630
+الهيمتوزايلين بقوة وتظهر في داخل الخلية بما يسمى
+
+391
+00:26:48,630 --> 00:26:52,350
+الـ L-E body زي ما انتوا سايفين هذا الجسم هذا هو
+
+392
+00:26:52,350 --> 00:26:55,870
+كل الـ L-E cell من إيش بتكون؟ من الخلية الأصلية
+
+393
+00:26:55,870 --> 00:27:01,010
+نوات الخلية الأصلية هذه نواتها مزاحة للأطراف وفي
+
+394
+00:27:01,010 --> 00:27:05,990
+الوسط الـ Engulfed nucleus بتكون فاتحة و متجانسة
+
+395
+00:27:05,990 --> 00:27:08,570
+لأنه صير لها فاج و سيتازز و المرحلة اللي بعدها
+
+396
+00:27:08,570 --> 00:27:12,340
+كانت بتصير لها lysisتمام فهد هي الـ L-E cell
+
+397
+00:27:12,340 --> 00:27:15,380
+detection of L-E cell made through microscopic
+
+398
+00:27:15,380 --> 00:27:19,560
+examination ممكن طبعا أشوفها تحت الميكروسكوب هذه
+
+399
+00:27:19,560 --> 00:27:23,560
+الطريقة كانت تستخدم قديما ويعتمدوها بشكل أساسي
+
+400
+00:27:23,560 --> 00:27:26,380
+لتشخيص ال systemic lobus لكن الآن في عندنا تحصات
+
+401
+00:27:26,380 --> 00:27:30,900
+أقوى زي الـ antinuclear antibody نكشف عنه عملية ال
+
+402
+00:27:30,900 --> 00:27:34,420
+diagnosis لل systemic lobus شوية معقدة لأنه ممكن
+
+403
+00:27:34,420 --> 00:27:39,610
+تدخل مع other autoimmune diseasesهنا بذكرلك يعني
+
+404
+00:27:39,610 --> 00:27:44,290
+كيف الـ diagnosis تدرج يعني مين اللي بيقرر كيف ال
+
+405
+00:27:44,290 --> 00:27:46,650
+diagnosis يكون اللي هي American College of
+
+406
+00:27:46,650 --> 00:27:50,270
+Rheumatology ACR هذه بتحط الكريتيريا اللي بيتم
+
+407
+00:27:50,270 --> 00:27:53,810
+بناء عليها ال diagnosis في كريتيريا انحطت في الـ
+
+408
+00:27:53,810 --> 00:27:57,270
+82 في كريتيريا في الـ 97 الكريتيريا اللي احنا
+
+409
+00:27:57,270 --> 00:28:02,610
+هنحكي عنها اليوم اللي هي أخر كريتيريا 2012 هنا
+
+410
+00:28:02,610 --> 00:28:06,970
+بقولك عشان أنا أشخص مريض systemic lobosisلازم
+
+411
+00:28:06,970 --> 00:28:12,570
+يتوفر عنده شغلة من تنتين الشغلة الأولى لازم يتحقق
+
+412
+00:28:12,570 --> 00:28:17,730
+فيها شغلتان مع بعض اللي هم أول حاجة أخد بيوبسي من
+
+413
+00:28:17,730 --> 00:28:21,030
+الـ kidney يثبت في الـ biopsy هذا إنه فيه lobus
+
+414
+00:28:21,030 --> 00:28:26,290
+nephritis بالإضافة لإنه أخد فحوصات المناعة زي الـ
+
+415
+00:28:26,290 --> 00:28:30,710
+ANA أو Anti-Double Strand DNA تكون positive تمام؟
+
+416
+00:28:30,710 --> 00:28:34,590
+إذن هذا الشرط الأول إذا تحقق بيكون هذا مريض lobus
+
+417
+00:28:35,040 --> 00:28:38,300
+طيب، في طريقة تانية أو في شرط تاني برضه لو تحقق
+
+418
+00:28:38,300 --> 00:28:43,540
+بيكون مريض لوبس قطة عندنا 11 صفة أو 11 criteria
+
+419
+00:28:43,540 --> 00:28:48,400
+لمرضى الـ Lobes إذا توفر منهم أربع criteria بيكون
+
+420
+00:28:48,400 --> 00:28:54,060
+مريض لوبس بشرط إن الأربع هدول يشملوا على الأقل
+
+421
+00:28:54,060 --> 00:29:00,100
+واحد مناعي وواحد يعني بيشمل clinical symptoms أو
+
+422
+00:29:00,100 --> 00:29:04,560
+أعراض كيف يعني؟يعني مابنفعش يكون الشخص عنده كل الـ
+
+423
+00:29:04,560 --> 00:29:06,880
+Clinical Symptoms كل الأربع هدول المتوفرين
+
+424
+00:29:06,880 --> 00:29:09,680
+Clinical Symptoms لمّا أجي أعمل فحص المناعة على E
+
+425
+00:29:09,680 --> 00:29:13,880
+Negative ممنفعش يعني لازم يتوفر حاجات مناعية
+
+426
+00:29:13,880 --> 00:29:16,860
+Positive بالإضافة لأعراض حاجات Serocytes، طب أيش
+
+427
+00:29:16,860 --> 00:29:20,500
+هذي الـ Crystallia؟ إيش يعني الـ Serocytes؟ التهاب
+
+428
+00:29:20,500 --> 00:29:24,400
+في الـ Serous Fluids تشمل لـ Plural Membrane الـ
+
+429
+00:29:24,400 --> 00:29:28,280
+Serous Membrane عفواً تشمل لـ Plural Membrane الـ
+
+430
+00:29:28,280 --> 00:29:31,730
+Pericardial Membrane هذه ممكن نختبرهامن خلال الـ
+
+431
+00:29:31,730 --> 00:29:35,810
+electrocardiogram أو صور الأشعة شغلة تانية الـ
+
+432
+00:29:35,810 --> 00:29:39,950
+oral ulcers خاصة في منطقة الـ nasopharynx و عادة
+
+433
+00:29:39,950 --> 00:29:44,470
+بتكون vaneless رقم تلاتة arthritis التهاب في
+
+434
+00:29:44,470 --> 00:29:48,350
+المفاصل وبيتميز التهاب المفاصل عندهم على خلاف
+
+435
+00:29:48,350 --> 00:29:50,530
+الموجود في الـ rheumatoid arthritis انه non
+
+436
+00:29:50,530 --> 00:29:55,740
+-erosive يعني لا يؤدي إلى تآكل في العظامكيف شكل
+
+437
+00:29:55,740 --> 00:29:58,420
+الـ Arthritis بدو يكون أنه في عندهم على الأقل
+
+438
+00:29:58,420 --> 00:30:03,200
+مفصلين أو أكثر تأثروا صار فيهم التهاب وصار فيهم
+
+439
+00:30:03,200 --> 00:30:07,880
+تضخم وتورم طيب الشغل الرابع اللي هي الـ
+
+440
+00:30:07,880 --> 00:30:13,040
+Photosensitivity أنه هذا الشخص لو تعرض لضوء الشمس
+
+441
+00:30:13,040 --> 00:30:17,620
+حيصير عنده اللي هي الـ Rash المعروفة عند مرضاء الـ
+
+442
+00:30:17,620 --> 00:30:21,480
+Lubus اللي هو تهيش في الجلد مع حمرار رقم خمسة
+
+443
+00:30:21,480 --> 00:30:25,850
+BloodDisorders زي Lycopenia، Lympopenia،
+
+444
+00:30:25,850 --> 00:30:29,450
+Thrombocytopenia طبعا كل هدول ولا واحد فيهم لسه
+
+445
+00:30:29,450 --> 00:30:32,650
+مناعي خدوا بالكم كلها عبارة عن أعراض مالهاش علاقة
+
+446
+00:30:32,650 --> 00:30:36,950
+بالفقوسات المناعية طيب
+
+447
+00:30:36,950 --> 00:30:42,170
+من الخصائص الأخرى اللي وضعت الـ Renal Involvement
+
+448
+00:30:42,170 --> 00:30:46,070
+Renal Involvement يعني إنه في مشاكل في الكدن ممكن
+
+449
+00:30:46,070 --> 00:30:49,070
+تشمل protein urea plus three protein في الـ
+
+450
+00:30:49,070 --> 00:30:53,420
+dipstickأو وجود Cellular Cast زي الـ RBCs Cast و
+
+451
+00:30:53,420 --> 00:30:58,680
+الـ YPCs Cast طبعا يعني ممكن هذه بتتم تقييمها من
+
+452
+00:30:58,680 --> 00:31:02,640
+خلال الدكتور المعالج الـ Neurological Disorder
+
+453
+00:31:02,640 --> 00:31:05,740
+يعني كتير منهم بتصير عندهم أغمقات متكررة بيصير
+
+454
+00:31:05,740 --> 00:31:10,760
+عندهم اكتئاب غير مبرر مشاكل عصبية بتصاحب اللو بس
+
+455
+00:31:10,760 --> 00:31:14,020
+لأن الـ Antibodies ممكن تأثر على الجهاز العصبيمال
+
+456
+00:31:14,020 --> 00:31:17,780
+الراش اللى هى الـ Fixed Erythremia اللى موجودة على
+
+457
+00:31:17,780 --> 00:31:21,180
+الخدين على الوجه على الوجنتين وعلى الأنف اللى هى
+
+458
+00:31:21,180 --> 00:31:26,400
+مخدة شكل Butterfly ديسكويد راش راش بهذا الشكل
+
+459
+00:31:26,400 --> 00:31:32,480
+بتكون دائرية مرتفعة الحواف مع عاملة Scar في الوسط
+
+460
+00:31:32,900 --> 00:31:35,700
+الـ Criteria اللي احنا حكينا فيها التسعة قبلها
+
+461
+00:31:35,700 --> 00:31:39,280
+كانت عبارة عن Clinical Criteria نيجي الآن لآخر
+
+462
+00:31:39,280 --> 00:31:43,640
+تنين اللي هم الـ Immunological Criteria الأول وجود
+
+463
+00:31:43,640 --> 00:31:48,060
+Anti-Nuclear Antibodies بـ High Titer يعني كل ما
+
+464
+00:31:48,060 --> 00:31:50,340
+كان الـ Titer أعلى بيكون ال diagnosis more
+
+465
+00:31:50,340 --> 00:31:55,920
+specific يكون الـ Titer فائل 160 شغلة تانية وجود
+
+466
+00:31:55,920 --> 00:32:01,300
+يعني أنواع أخرى من الـ Antibodiesالمصاحبة لـ
+
+467
+00:32:01,300 --> 00:32:05,600
+Systemic Lobes زي Double-Strand DNA Anti-Double
+
+468
+00:32:05,600 --> 00:32:10,300
+-Strand DNA Anti-Smith Antibodies Anti
+
+469
+00:32:10,300 --> 00:32:12,860
+-phospholipids زي الـ Anti-cardiolipin والـ Anti
+
+470
+00:32:12,860 --> 00:32:18,400
+-lobes هذه راح قدنا نحكي عنها بشكل مفصل أكتر الـ
+
+471
+00:32:18,400 --> 00:32:21,340
+Antibodies الأخرى اللي بتوجد positive في Systemic
+
+472
+00:32:21,340 --> 00:32:25,460
+Lobes طيب، هالـ A11 اللي حكينا فيهم عشان أشخص
+
+473
+00:32:25,460 --> 00:32:29,730
+Systemic Lobes لازم يتوفر أربعةالأربع هدول يكونوا
+
+474
+00:32:29,730 --> 00:32:34,770
+موزعين بين التسعة اللي حكيناهم قبل اللي عبارة عن
+
+475
+00:32:34,770 --> 00:32:37,610
+الـ Clinical Criteria والتنتين هدول يعني لازم
+
+476
+00:32:37,610 --> 00:32:42,650
+يتحقق على الأقل واحدة Clinical Criteria واحدة من
+
+477
+00:32:42,650 --> 00:32:46,290
+الـ Immunological Criteria وجود Antibody يعني وجود
+
+478
+00:32:46,290 --> 00:32:51,350
+أربع مع بعض من هذلك مع الـ Antibodies Negative
+
+479
+00:32:51,350 --> 00:32:55,660
+مابدلش على له بس يعني لازم يتواجدواclinical
+
+480
+00:32:55,660 --> 00:33:00,020
+criteria و immunological criteria على الأقل واحدة
+
+481
+00:33:00,020 --> 00:33:04,880
+من كل نوع والمجموع يكون أربعة criteria عشان نشخص
+
+482
+00:33:04,880 --> 00:33:10,240
+systemic low pass عندي
+
+483
+00:33:10,240 --> 00:33:13,220
+هنا surgical tests اللي ممكن تعطيني positive في
+
+484
+00:33:13,220 --> 00:33:17,440
+systemic low pass هناخدها يعني مش هيكون مش هطلب
+
+485
+00:33:17,440 --> 00:33:20,740
+منكم تفاصيلها بس يعني مش كل الأشياء هطلبها منكم
+
+486
+00:33:20,740 --> 00:33:26,090
+أول حاجة ال ANAالـ ANA يعتبر كـ Screening Test الـ
+
+487
+00:33:26,090 --> 00:33:30,570
+Sensitivity لإله 95% لكن إذا أعطاكي Positive بدون
+
+488
+00:33:30,570 --> 00:33:35,450
+Clinical Criteria معنى الكلام إنه يعني لا يدل على
+
+489
+00:33:35,450 --> 00:33:38,510
+شيء طبعاً لازم إذا أعطاكي Positive تدوري علي
+
+490
+00:33:38,510 --> 00:33:41,450
+Clinical Criteria إذا كانت موجودة فبالتالي ممكن
+
+491
+00:33:41,450 --> 00:33:45,970
+تكون حالة Lobus مافيش Clinical Criteria إذا مش
+
+492
+00:33:45,970 --> 00:33:49,830
+Lobus طيب Anti-Double Strand DNA إله Specificity
+
+493
+00:33:49,830 --> 00:33:54,920
+عالية بس الـ Sensitivity تبعته بس 70%وطبعاً بتغير
+
+494
+00:33:54,920 --> 00:33:59,380
+ال level تبعه حسب نشاط ال disease Anti-smooth
+
+495
+00:33:59,380 --> 00:34:05,800
+muscle هذا أقل specificity بس 30 يعني specificity
+
+496
+00:34:05,800 --> 00:34:08,960
+تبعته قليلة وال sensitivity برضه قليلة بس 30 إلى
+
+497
+00:34:08,960 --> 00:34:15,340
+40% Anti-SSA أو Anti-Rigosomal بيه Anti-RNP Anti
+
+498
+00:34:15,340 --> 00:34:18,720
+-cardiolipin لوبس Anti-coagulant هذه كلها
+
+499
+00:34:18,720 --> 00:34:22,670
+antibodies ممكن تكون positive في مرض اللوبسالـ
+
+500
+00:34:22,670 --> 00:34:25,190
+Direct Combs Test برضه بيكون Positive، Anti
+
+501
+00:34:25,190 --> 00:34:28,050
+-Histone، Antibodies Positive بدون تفاصيل، مجرد
+
+502
+00:34:28,050 --> 00:34:31,170
+ذكر، يعني أنه تعرف أمتى الـ Antibodies اللي بتكون
+
+503
+00:34:31,170 --> 00:34:38,930
+موجودة في مرضى الـ Lobus فخوصات أخرى يعني بتستخدم
+
+504
+00:34:38,930 --> 00:34:43,410
+في ال diagnosis للـ Lobus الـ CBC طبعا الـ CBC
+
+505
+00:34:43,410 --> 00:34:47,190
+عشان نشوف الليكوبينيا، ثرمبوسيتوبينيا ممكن نعمل
+
+506
+00:34:47,190 --> 00:34:49,930
+سيرام كرياتينين عشان نشوف ال kidney function urine
+
+507
+00:34:49,930 --> 00:34:55,660
+analysis عشان نشوف وضع الكدنىطبعا ممكن كمان نشوف
+
+508
+00:34:55,660 --> 00:34:59,560
+الـ inflammatory markers اللي هي CRP و ESR عادة
+
+509
+00:34:59,560 --> 00:35:03,700
+بيكونوا positive مرتفعين الـ complement components
+
+510
+00:35:03,700 --> 00:35:08,220
+ممكن تساعدني لأن الـ C3 و C4 عادة بتنزل في ال
+
+511
+00:35:08,220 --> 00:35:12,540
+patient اللي عندهم active Lubus لأنه بيصير لها
+
+512
+00:35:12,540 --> 00:35:15,750
+consumption بيصير لها استهلاكلأن الـ Immune
+
+513
+00:35:15,750 --> 00:35:18,950
+Complexes بتتكون باستمرار والـ Immune Complexes
+
+514
+00:35:18,950 --> 00:35:22,110
+بتباعها تنشيط للـ Complement مما يؤدي لاستهلاك الـ
+
+515
+00:35:22,110 --> 00:35:24,990
+Complement Components وإنه يسير في هذه الشخصية نجي
+
+516
+00:35:24,990 --> 00:35:29,790
+للـ Diagnosis الصحيح أو الدقيق لقائمة الـ
+
+517
+00:35:29,790 --> 00:35:33,550
+Antibodies اللي بتتكون في الـ System Globus نعرف
+
+518
+00:35:33,550 --> 00:35:37,910
+كيف بنشتغلها هذه الـ Antibodies بتنشغل عن طريق الـ
+
+519
+00:35:37,910 --> 00:35:41,150
+Indirect Immunofluorescence Assay يعني تعتبر الـ
+
+520
+00:35:41,150 --> 00:35:47,610
+Gold Standard للـ Diagnosis طيببداية هنا طبعا
+
+521
+00:35:47,610 --> 00:35:51,930
+قائمة باسماء الـ Antibodies بداية الـ Antibodies
+
+522
+00:35:51,930 --> 00:35:54,830
+هذه إذا أعطتني Negative يعني الـ Antibody مش موجود
+
+523
+00:35:54,830 --> 00:35:59,490
+تمام؟ الـ Antibody لما بيتفاعل مع الـ Antigen اللي
+
+524
+00:35:59,490 --> 00:36:02,250
+أنا بحطه عشان أكشف من خلاله على الـ Antibody
+
+525
+00:36:02,250 --> 00:36:07,530
+هيعطيني Specific Fluorescence Pattern يعني شكل
+
+526
+00:36:07,530 --> 00:36:11,710
+الوميد أو شكل الإضاءة هتكون مختلفة من Antibody
+
+527
+00:36:11,710 --> 00:36:16,690
+لAntibody طب ليش فيه اختلاف؟في اختلاف طبعاً هذا
+
+528
+00:36:16,690 --> 00:36:19,930
+الاختلاف أنا بشوفه تحت المايكروسكوب بعد ما أحضر
+
+529
+00:36:19,930 --> 00:36:23,390
+الشريحة بشوفها تحت المايكروسكوب الاختلاف هذا جاء
+
+530
+00:36:23,390 --> 00:36:26,770
+من إيش؟ من توزيع الـ Antigen في داخل الخلية فلقيت
+
+531
+00:36:26,770 --> 00:36:29,350
+أنا على سبيل المثال بدور على Antigen موجود في
+
+532
+00:36:29,350 --> 00:36:33,150
+النواة أكيد الـ Antibody هيتفاعل مع الـ Antigen
+
+533
+00:36:33,150 --> 00:36:36,170
+الموجود في داخل النواة وتكون الإضاءة داخل النواة
+
+534
+00:36:36,170 --> 00:36:38,910
+تمام؟ لو كان في الـCytoplasm هتكون الإضاءة في
+
+535
+00:36:38,910 --> 00:36:44,380
+الـCytoplasm كويس؟ طيبالنقطة الأخيرة هذه بتحكي أنه
+
+536
+00:36:44,380 --> 00:36:47,220
+أنا عشان أكشف عن الـ Antibodies هذه أي واحد من الـ
+
+537
+00:36:47,220 --> 00:36:51,440
+Antibodies لازم أكون مجهزة له Antigen مثبت على الـ
+
+538
+00:36:51,440 --> 00:36:56,640
+slide الـ Antigen هذا بيحس أنه يتفاعل معاه وبعد
+
+539
+00:36:56,640 --> 00:37:00,060
+هيك أربطه ب secondary antibody label secondary
+
+540
+00:37:00,060 --> 00:37:05,220
+antibody و أشوف ال fluorescence الشريحة التالية
+
+541
+00:37:05,220 --> 00:37:08,740
+بتحكي عن ال substrate اللي أنا بدي استخدمها أو ال
+
+542
+00:37:08,740 --> 00:37:11,220
+Antigens اللي أنا بدي استخدمها للشغل
+
+543
+00:37:15,280 --> 00:37:19,620
+طيب، هنا قائمة بتقولك أمثلة على الـ Substrate
+
+544
+00:37:19,620 --> 00:37:23,040
+المستخدم طبعاً زي ما اتفقنا الـ Substrate هو عبارة
+
+545
+00:37:23,040 --> 00:37:26,680
+عن خلايا أو نسيج بيحتوي على الـ Antigen وثبت على
+
+546
+00:37:26,680 --> 00:37:30,300
+slide بضيف عليه العينة بتاعتي إذا كان الـ Antibody
+
+547
+00:37:30,300 --> 00:37:33,800
+موجود، حيصير ارتباط بعد ذلك بضيف ال conjugated
+
+548
+00:37:33,800 --> 00:37:37,100
+antibody اللي هو معموله labelled وحيصير التفاعل
+
+549
+00:37:37,100 --> 00:37:41,810
+يعطيني إضاءة إذا كان موجودمثلًا لو أنا بدي أدور
+
+550
+00:37:41,810 --> 00:37:45,790
+على الـ Anti-Double-Strand DNA في عندي نوع من
+
+551
+00:37:45,790 --> 00:37:48,750
+الأوليات باستخدمه اللي هو Crescida Lucila
+
+552
+00:37:48,750 --> 00:37:55,370
+Substrate الـ ANA ممكن أستخدم Hip2 Cells خلايا من
+
+553
+00:37:55,370 --> 00:37:59,430
+اللفر أو Mouse Stomach Kidney Substrate يعني يكون
+
+554
+00:37:59,430 --> 00:38:02,710
+الـ Substrate فيه خلايا من Mouse Stomach and
+
+555
+00:38:02,710 --> 00:38:07,860
+Kidneyالـ ABL ASMA AMA On Mouse Stomach Kidney
+
+556
+00:38:07,860 --> 00:38:12,600
+Substrate Anti-LKM Mouse Liver Stomach Kidney
+
+557
+00:38:12,600 --> 00:38:16,900
+Substrate الـ ANCA Neutrophil Substrate
+
+558
+00:38:16,900 --> 00:38:21,950
+Antithyroid Antibodiesلأنه ثيرويد Antibodies
+
+559
+00:38:21,950 --> 00:38:25,490
+فبديجيب ثيرويد تساعل الـ Antigen مع الـ Antibody
+
+560
+00:38:25,490 --> 00:38:28,930
+في الـ indirect immunofluorescence زي ما حكينا كل
+
+561
+00:38:28,930 --> 00:38:33,510
+Antibody اللي هو pattern معين في اللون يعني أو في
+
+562
+00:38:33,510 --> 00:38:35,710
+الإضاءة اللي بتظهر أو في ال fluorescence اللي بظهر
+
+563
+00:38:35,710 --> 00:38:39,570
+ممكن تبقى diffuse، homogeneous يعني اللون متجانس
+
+564
+00:38:39,570 --> 00:38:45,290
+ممكن يبقى على شكل رم يعني إضاءة محيطة بالنواة
+
+565
+00:38:45,290 --> 00:38:51,160
+spicled، منقط، nuclearالنواء يعني جاية عند النوية
+
+566
+00:38:51,160 --> 00:38:55,440
+أو منطقة النوية هي اللي مضاقة Centromeric جاية في
+
+567
+00:38:55,440 --> 00:38:57,640
+منطقة الـ Centromere رح ناخدها لقيت أمثل عليها
+
+568
+00:38:57,640 --> 00:39:00,200
+طبعا كلها هذه عبارة عن Anti-nuclear antibodies
+
+569
+00:39:00,200 --> 00:39:04,080
+يعني antibodies لأشياء موجودة في داخل النواء انشوف
+
+570
+00:39:04,080 --> 00:39:11,920
+كيف شكل ال reaction بيكون Peripheral أو رم على شكل
+
+571
+00:39:11,920 --> 00:39:17,380
+خط رفيع حوالين النواء زي الـ Anti-DNAفي حالات الـ
+
+572
+00:39:17,380 --> 00:39:20,520
+Systemic Lobes Homogeneous، Diffused زي الـ Anti
+
+573
+00:39:20,520 --> 00:39:26,240
+-DNA والـ Anti-Histone Spicaled، منقط زي مجموعة
+
+574
+00:39:26,240 --> 00:39:31,880
+اللي هي الـ Anti-SM والـ Anti-Rnode وAnti-GO يعني
+
+575
+00:39:31,880 --> 00:39:34,840
+مش كلهم تحفظوهم هدال بحدد ال combination اللي
+
+576
+00:39:34,840 --> 00:39:39,220
+مطلوب Centromeric بيكون حوالين الـ Centromere أو
+
+577
+00:39:39,220 --> 00:39:43,490
+بهذا الشكل Anti-centromeric filicrist syndromeالـ
+
+578
+00:39:43,490 --> 00:39:47,690
+Nuclear بيكون عند الـ Nuclear الـ Nuclei طيب
+
+579
+00:39:47,690 --> 00:39:50,430
+خلّينا نشوف بعض النتائج كيف بيكون شكلها تحت
+
+580
+00:39:50,430 --> 00:39:56,290
+المايكروسكوب هذه مافيش أي وميد أخضر إذا النتيجة
+
+581
+00:39:56,290 --> 00:40:00,870
+Negative نفس الفحز بس نتيجة Positive زي ما أنتوا
+
+582
+00:40:00,870 --> 00:40:04,890
+شايفين اللون الأخضر هذا بيعني Positive وشايفين أن
+
+583
+00:40:04,890 --> 00:40:09,110
+هذه الخلية والنواة كلها مضاءة بشكل Homogeneous إذا
+
+584
+00:40:09,110 --> 00:40:11,190
+هذا الـ Diffused أو Homogeneous
+
+585
+00:40:15,670 --> 00:40:20,710
+Speckled يعني انه منقطة مش homogenous في مناطق
+
+586
+00:40:20,710 --> 00:40:28,730
+مضيئة ومناطق معتمة وهذه برضه Speckled هذه
+
+587
+00:40:28,730 --> 00:40:33,790
+Anti-nuclear اللي هي ضد النوية ال antibodies زي ما
+
+588
+00:40:33,790 --> 00:40:39,870
+انتوا شايفين منطقة النيوكليولاي هي المضاقة هتشوفي
+
+589
+00:40:39,870 --> 00:40:43,550
+كل ال field معتم إلا هذه المنطقة هي هذه rim
+
+590
+00:40:43,550 --> 00:40:48,100
+pattern علىحوالين النواة الـ Lawn جاي حوالين
+
+591
+00:40:48,100 --> 00:40:52,560
+النواة نيجي
+
+592
+00:40:52,560 --> 00:40:58,100
+هنا Antibodies للـ Double Strand DNA هنا المستخدم
+
+593
+00:40:58,100 --> 00:41:00,680
+السبسترات زي ما قلنا اللي هي الـ Crescedia Lucila
+
+594
+00:41:00,680 --> 00:41:05,160
+اللي هو نوع من البدائيات هاي ال positive result
+
+595
+00:41:05,160 --> 00:41:08,480
+هنا هذه negative double strand DNA مافيش فيها
+
+596
+00:41:08,480 --> 00:41:11,060
+إضاءة زي الصورة اللي قبلها الصورة اللي قبلها كانت
+
+597
+00:41:11,060 --> 00:41:12,940
+فيها إضاءة هذه مافيش فيها إضاءة
+
+598
+00:41:16,120 --> 00:41:20,220
+Anti-neutrophil-cytoplasmic antibodies أكيد
+
+599
+00:41:20,220 --> 00:41:23,260
+نيوتروفيل سايتو بلازميك antibodies إذا ال
+
+600
+00:41:23,260 --> 00:41:25,500
+antibodies للسايتو بلازم عشان هيك هتلاقي الإضاءة
+
+601
+00:41:25,500 --> 00:41:29,260
+في السايتو بلازم مش في النواة يسموها الانكا لاحظين
+
+602
+00:41:29,260 --> 00:41:33,880
+الإضاءة وين في السايتو بلازم عفوا يعافى يعافى هيك
+
+603
+00:41:33,880 --> 00:41:38,020
+بنكون خلصنا ال diagnosis ل ال autoimmune diseases
+
+604
+00:41:38,020 --> 00:41:42,140
+احنا اختصرنا كتير من المحاضرة ان شاء الله يارب
+
+605
+00:41:42,140 --> 00:41:44,220
+تكون الأمور واضحة يعني
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/4YOgadC8Prk_raw.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/4YOgadC8Prk_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..f34508759afbc92a4212ddaca47a78ab00e26f0b
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/4YOgadC8Prk_raw.srt
@@ -0,0 +1,1708 @@
+1
+00:00:01,310 --> 00:00:07,010
+بسم الله الرحمن الرحيم هذه المحاضرة ستتناول مجموعة
+
+2
+00:00:07,010 --> 00:00:12,150
+من الفحوصات التي لابنا نتطرق لها خلال الفصل تشمل
+
+3
+00:00:12,150 --> 00:00:14,990
+مثلا الـ complement fixation الـ neutralization
+
+4
+00:00:14,990 --> 00:00:19,730
+and others نيجي
+
+5
+00:00:19,730 --> 00:00:23,410
+بداية للـ complement fixation test complement
+
+6
+00:00:23,410 --> 00:00:28,410
+fixation test يعني أول ما بدوا يستخدموا استخدموا
+
+7
+00:00:28,410 --> 00:00:36,190
+للـ serology of syphilisتم إدخاله في عام 1909 الآن
+
+8
+00:00:36,190 --> 00:00:39,390
+هذا الفحص ظل فترة طويلة جدا فقط يستخدم للـ
+
+9
+00:00:39,390 --> 00:00:45,130
+syphilis بعد هك تم تطويره من أجل استخدامه لفحوصات
+
+10
+00:00:45,130 --> 00:00:49,470
+serology و virology أخرى الآن الـ complement
+
+11
+00:00:49,470 --> 00:00:54,130
+fixation test يعني بيتميز بإنه أول إشي it is
+
+12
+00:00:54,130 --> 00:00:57,150
+convenient and rapid to perform يعني هو مناسب
+
+13
+00:00:57,150 --> 00:01:03,820
+للعمل وسهل إنه ينشغلالتطبيقات التجارية والتجارة
+
+14
+00:01:03,820 --> 00:01:06,760
+التجارية صغيرة يعني ما بحتاج عندي تكليفات كتير أو
+
+15
+00:01:06,760 --> 00:01:10,340
+تجارة تجارة تجارة وأجهزة أو أشياء زي هكذا تجارة
+
+16
+00:01:10,340 --> 00:01:12,260
+تجارة تجارة تجارة تجارة تجارة تجارة تجارة تجارة
+
+17
+00:01:12,260 --> 00:01:12,600
+تجارة تجارة تجارة تجارة تجارة تجارة تجارة تجارة
+
+18
+00:01:12,600 --> 00:01:13,060
+تجارة تجارة تجارة تجارة تجارة تجارة تجارة تجارة
+
+19
+00:01:13,060 --> 00:01:15,420
+تجارة تجارة تجارة تجارة تجارة تجارة تجارة تجارة
+
+20
+00:01:15,420 --> 00:01:29,100
+تجارة تجارة تجارة تجارة تجارة تجارة
+
+21
+00:01:29,640 --> 00:01:34,080
+الـ Complement Fixation Test عادة يستخدم للبحث عن
+
+22
+00:01:34,080 --> 00:01:37,160
+Antibodies في الـ Patient Serum يعني أنا بدور على
+
+23
+00:01:37,160 --> 00:01:42,680
+عينة Antibodies شو بجيب؟ بجيب Antigen و بجيب
+
+24
+00:01:42,680 --> 00:01:46,900
+Complement تمام؟ عشان أنا بدي بعد الـ Antigen
+
+25
+00:01:46,900 --> 00:01:50,160
+Antibody Reaction ما يصير يصير Complement Fixation
+
+26
+00:01:50,160 --> 00:01:54,380
+الآن إذا اتفاعل الـ Antigen مع الـ Antibody وصار
+
+27
+00:01:54,380 --> 00:01:57,900
+Complement Fixation بدي أخبر هل صار Complement
+
+28
+00:01:57,900 --> 00:02:01,500
+Fixation ولا لأ؟كيف؟ احنا عارفين ان الـ complement
+
+29
+00:02:01,500 --> 00:02:05,940
+لما يصير لها fixation بيكون لها cytolytic activity
+
+30
+00:02:05,940 --> 00:02:12,200
+يعني بتعمل license للـ blood cells، مظبوط بتعمل
+
+31
+00:02:12,200 --> 00:02:16,300
+license لخلايا الدم فانا بضيف خلايا الدم وأشوف هل
+
+32
+00:02:16,300 --> 00:02:20,480
+حصل license ولا لأ طيب، شوف، this test is based on
+
+33
+00:02:20,480 --> 00:02:24,620
+the use of complement a biological labile serum
+
+34
+00:02:24,620 --> 00:02:30,000
+factorthat causes the immune cytolysis يعني بتسبب
+
+35
+00:02:30,000 --> 00:02:33,340
+الـ cytolysis للخلايا lysis of antibody-coated
+
+36
+00:02:33,340 --> 00:02:38,660
+cells طبعا طيب احنا لسه بنحكي ال principle عندنا
+
+37
+00:02:38,660 --> 00:02:42,320
+راح نفهم بالتفصيل الخطوات اللي بتتم فيها ال
+
+38
+00:02:42,320 --> 00:02:46,200
+complement fixation ال complement fixation بنعمل
+
+39
+00:02:46,200 --> 00:02:51,380
+الفحص على two steps أول حاجة الخطوة الأولى اللي هي
+
+40
+00:02:51,380 --> 00:02:55,390
+خطوة ال complement fixationالخطوة التانية بدي أشوف
+
+41
+00:02:55,390 --> 00:02:59,730
+هل حصل complement fixation ولا ماحصلش إذا first
+
+42
+00:02:59,730 --> 00:03:04,270
+step complement fixation a non-antigen إذا أول
+
+43
+00:03:04,270 --> 00:03:08,570
+حاجة بتلزمني أني بدي أجيب antigen بجيب ال patient
+
+44
+00:03:08,570 --> 00:03:13,570
+serum بس شرط لما أجيب ال patient serum يا بنات أني
+
+45
+00:03:13,570 --> 00:03:18,250
+أعمل inactivation لل complement اللي فيه ليش؟ لأني
+
+46
+00:03:18,250 --> 00:03:23,120
+أنا بدي أعمل standardization للفحصكيف أعمله
+
+47
+00:03:23,120 --> 00:03:27,760
+standardization؟ بدي أجيب complement بكمية محددة
+
+48
+00:03:27,760 --> 00:03:30,780
+وأنا اللي أضيفها قداش أنا بدي complement أضيف
+
+49
+00:03:30,780 --> 00:03:34,120
+ألاقيت لو أنا بدي أستخدم ال patient serum
+
+50
+00:03:34,120 --> 00:03:36,520
+complement اللي موجودة أصلا في ال patient أنا ما
+
+51
+00:03:36,520 --> 00:03:40,260
+بعرف ال variation بين ال individuals ماعرفش كل شخص
+
+52
+00:03:40,260 --> 00:03:44,180
+قداش عنده فرق complement عن التاني فأنا مابدأ أخلي
+
+53
+00:03:44,180 --> 00:03:47,640
+تركيز ال complement factor يؤثر على النتيجة بتاعتي
+
+54
+00:03:47,640 --> 00:03:53,020
+فأنا بدي أعمل تثبيت للفحص standardizationفماش بعمل
+
+55
+00:03:53,020 --> 00:03:57,300
+أول حاجة بعملها بعمل inactivation للـ complement
+
+56
+00:03:57,300 --> 00:04:02,320
+الموجودة في الـ serum إذن وبضيف الـ antigen a non
+
+57
+00:04:02,320 --> 00:04:07,120
+-antigen and inactivated patient serum inactivated
+
+58
+00:04:07,120 --> 00:04:10,080
+إيش يعني؟ يعني أنا عملت inactivation للـ
+
+59
+00:04:10,080 --> 00:04:13,800
+complement الموجودة فيه are incubated with a
+
+60
+00:04:13,800 --> 00:04:16,860
+standardized limit amount of complement يعني بعد
+
+61
+00:04:16,860 --> 00:04:21,050
+هيك أنا بضيف كمية محددة من الـ complementكيف بنعمل
+
+62
+00:04:21,050 --> 00:04:26,770
+inactivation للـ patient serum عن طريق تسخينه على
+
+63
+00:04:26,770 --> 00:04:32,310
+56 درجة مئوية لـ 30 دقيقة هذه العملية راح تعمل
+
+64
+00:04:32,310 --> 00:04:36,010
+inactivation للـ endogenous complement which may
+
+65
+00:04:36,010 --> 00:04:40,170
+disrupt the calibration يعني ممكن يتأثر عندي على
+
+66
+00:04:40,170 --> 00:04:42,330
+ال calibration بتاع الفحص اللي هي ال complement
+
+67
+00:04:42,330 --> 00:04:44,330
+اللي موجود عند ال patient نفسه
+
+68
+00:04:47,800 --> 00:04:55,040
+الأن إذا كان الـ Serum يحتوي
+
+69
+00:04:55,040 --> 00:04:57,260
+على الـ Antibody هذا اللي بيعمل complement
+
+70
+00:04:57,260 --> 00:05:01,360
+activation الـ complement will be activated or
+
+71
+00:05:01,360 --> 00:05:06,120
+fixed by أنتجن antibody complex، صح؟ يعني هيتكون
+
+72
+00:05:06,120 --> 00:05:08,980
+أنتجن، هيتفاعل الـ antibody مع الانتجن ويصير
+
+73
+00:05:08,980 --> 00:05:14,160
+complement fixation howeverإذا لم يكن هناك أنطجان
+
+74
+00:05:14,160 --> 00:05:18,440
+في الـBasin Serum لن يكون هناك تصميم من انتجان
+
+75
+00:05:18,440 --> 00:05:21,360
+انتجان انتجان انتجان انتجان انتجان انتجان انتجان
+
+76
+00:05:21,360 --> 00:05:21,860
+انتجان انتجان انتجان انتجان انتجان انتجان انتجان
+
+77
+00:05:21,860 --> 00:05:23,100
+انتجان انتجان انتجان انتجان انتجان انتجان انتجان
+
+78
+00:05:23,100 --> 00:05:24,540
+انتجان انتجان انتجان انتجان انتجان انتجان انتجان
+
+79
+00:05:24,540 --> 00:05:24,760
+انتجان انتجان انتجان انتجان انتجان انتجان انتجان
+
+80
+00:05:24,760 --> 00:05:26,940
+انتجان انتجان انتجان انتجان انتجان انتجان انتجان
+
+81
+00:05:26,940 --> 00:05:41,840
+انتجان انتجان انتجان انتجان انتجان ان
+
+82
+00:05:42,190 --> 00:05:44,790
+هلقيت بنيجي على المرحلة التانية أو بيعطيكي إشارة
+
+83
+00:05:44,790 --> 00:05:48,270
+إيش اللي بيصير في المرحلة التانية اللي هي بنسميها
+
+84
+00:05:48,270 --> 00:05:52,090
+المرحلة التانية أنا قلتلكم هي الكشف مرحلة الأولى
+
+85
+00:05:52,090 --> 00:05:54,710
+أني أعمل ال reaction أنتج ال antibody و complement
+
+86
+00:05:54,710 --> 00:05:57,630
+fixation المرحلة التانية بدي أكشف هل حصل
+
+87
+00:05:57,630 --> 00:06:01,110
+complement fixation ولا محصلش المرحلة التانية
+
+88
+00:06:01,110 --> 00:06:04,590
+بنسميها indicator stage in the indicator stage
+
+89
+00:06:04,590 --> 00:06:08,790
+this complement will react with RBCs coated with
+
+90
+00:06:08,790 --> 00:06:13,260
+antibody to sheep RBCsيمكن الجملة هذه هتبقى مبهمة
+
+91
+00:06:13,260 --> 00:06:17,380
+لغاية ما نفهمها بالتفصيل يعني بقولك انه بعد هيك
+
+92
+00:06:17,380 --> 00:06:23,780
+بجيب خلايا shape coated بال antibody و بضيفها هلأ
+
+93
+00:06:23,780 --> 00:06:27,660
+إذا دلت ال compliment free هتعمل cytolysis للخلايا
+
+94
+00:06:27,660 --> 00:06:34,360
+هذه هنفهم الكلام هذا لو قدامك الآن
+
+95
+00:06:34,360 --> 00:06:39,080
+الصورة هذه بتوضح أشي اللي بصير أول حاجة في عندك
+
+96
+00:06:39,080 --> 00:06:44,000
+عينتين عينةاللي على الشمال موجود الـ Antibody فيها
+
+97
+00:06:44,000 --> 00:06:47,940
+العينة اللي على اليمين الـ Antibody مش موجود فيها
+
+98
+00:06:47,940 --> 00:06:52,600
+في القادة طبعا أنا عملت complement inactivation
+
+99
+00:06:52,600 --> 00:06:54,720
+اللي موجودة في السيرم الـ complement عملتلها
+
+100
+00:06:54,720 --> 00:06:57,640
+inactivation وضفت على الفحص الـ Antigen و الـ
+
+101
+00:06:57,640 --> 00:07:00,700
+complement في القادة في عندي احتمالان ان يصير
+
+102
+00:07:00,700 --> 00:07:03,480
+complement fixation لأن اتفاعل الـ Antigen مع الـ
+
+103
+00:07:03,480 --> 00:07:06,140
+Antibody زي العينة الـ positive اللي على الشمال
+
+104
+00:07:06,700 --> 00:07:09,640
+العين اللي على اليمين دلت الـ complement free ليش؟
+
+105
+00:07:09,640 --> 00:07:11,960
+لأن مافيش Antibody يتفعل مع الـ Ant لشان يعمل
+
+106
+00:07:11,960 --> 00:07:16,860
+fixation تمام؟ هذه المرحلة الأولى بنسميها
+
+107
+00:07:16,860 --> 00:07:21,060
+complement fixation stage المرحلة التانية اللي هي
+
+108
+00:07:21,060 --> 00:07:26,160
+ال indicator stage هلقت في ال indicator stage أنا
+
+109
+00:07:26,160 --> 00:07:32,780
+بجيب sheep RBCs تمام؟ و ال sheep RBCs هذه بضيف
+
+110
+00:07:32,780 --> 00:07:38,180
+معاها Antibody أو بتكون coated بال Antibodyالخلايا
+
+111
+00:07:38,180 --> 00:07:42,860
+هذه هتتفاعل طبعا الـ Antibody هذا هيعمل تفاعل مع
+
+112
+00:07:42,860 --> 00:07:45,520
+الـ Antigens اللي على سطح خلايا الـ RBCs بتاعة الـ
+
+113
+00:07:45,520 --> 00:07:49,340
+Shape و أضيفهم على ال reaction mixture الأول اللي
+
+114
+00:07:49,340 --> 00:07:52,720
+أنا كنت عمال بشتغل فيه هلقيتاش الوضع أو إيش صورة
+
+115
+00:07:52,720 --> 00:07:56,920
+ال reaction إيه اللي هتصير؟ طبعا إحنا قلنا العين
+
+116
+00:07:56,920 --> 00:07:59,360
+اللي على الشمال positive و العين اللي على اليمين
+
+117
+00:07:59,360 --> 00:08:02,820
+كانت negative positive يعني كان فيها antibody
+
+118
+00:08:02,820 --> 00:08:07,720
+العين اللي على اليمين ماكانش فيها antibodyفتطلعوا
+
+119
+00:08:07,720 --> 00:08:10,460
+في الـ YouTube نفسها فلقيت الـ reaction الأصلي
+
+120
+00:08:10,460 --> 00:08:14,980
+اللي حصل الـ Antigen اتفاعل مع الـ Antibody وعمل
+
+121
+00:08:14,980 --> 00:08:18,600
+complement fixation هلأ أنا باجب أضيف الشيء بـ
+
+122
+00:08:18,600 --> 00:08:24,580
+RBCs و الـ Antibody بتاعها أمام هنا في العينة الـ
+
+123
+00:08:24,580 --> 00:08:29,280
+Positive المفروض الـ complement كلها مرتبطة بالـ
+
+124
+00:08:29,280 --> 00:08:32,640
+Antigen Antibody Complex اللي اتكون بالأول يعني
+
+125
+00:08:32,640 --> 00:08:37,240
+مافيش عندي complement فيهفبالتالي الـ complement
+
+126
+00:08:37,240 --> 00:08:42,020
+هذه مش راح يصير لها fixation عن طريق خلايا الـ
+
+127
+00:08:42,020 --> 00:08:45,120
+sheep والـ antibodies أو يعني هلقت فيه انه كأنه
+
+128
+00:08:45,120 --> 00:08:48,140
+two reactions صايرين ال reaction الأولاني عامل
+
+129
+00:08:48,140 --> 00:08:51,500
+complement fixation ال reaction التاني إذا كان ال
+
+130
+00:08:51,500 --> 00:08:54,680
+complement موجودة هيعمل fixation ويصير license
+
+131
+00:08:54,680 --> 00:08:57,760
+للخلايا إذا كان ال complement مش موجودة مش هيعمل
+
+132
+00:08:57,760 --> 00:09:01,020
+fixation طيب في ال reaction mixture الأولي اللي هو
+
+133
+00:09:01,020 --> 00:09:04,330
+ال positive هل فيه complement؟لأ مافيش compliment
+
+134
+00:09:04,330 --> 00:09:08,210
+لأن الـ compliment already مرتبطة ب reaction الأول
+
+135
+00:09:08,210 --> 00:09:10,510
+اللي هو تاع ال antibody تاع ال patients مع ال
+
+136
+00:09:10,510 --> 00:09:13,430
+antigen فبالتالي تم استهلاك ال compliment في
+
+137
+00:09:13,430 --> 00:09:19,230
+المرحلة الأولى عشان هيك مش هيصير license بينما لو
+
+138
+00:09:19,230 --> 00:09:23,810
+كان ال reaction من الأساس negative يعني ال antigen
+
+139
+00:09:23,810 --> 00:09:26,910
+اللي أنا أضفته مالقاش antibody يرتبط فيه هتظل ال
+
+140
+00:09:26,910 --> 00:09:31,110
+compliment free ولمّا أنا أجي أضيف الشيء ب RBCs مع
+
+141
+00:09:31,110 --> 00:09:35,430
+ال antibodyإيش هيصير؟ هيصير complement activation
+
+142
+00:09:35,430 --> 00:09:40,690
+هترتبط الـ complement وتعمل license للخلايا تمام؟
+
+143
+00:09:40,690 --> 00:09:45,850
+إذا النتيجة، في عندي النتيجة الـ positive all
+
+144
+00:09:45,850 --> 00:09:48,650
+available complement is fixed by the antigen
+
+145
+00:09:48,650 --> 00:09:51,910
+antibody reaction اللي هو الأول no hemolysis
+
+146
+00:09:51,910 --> 00:09:55,850
+occurs ماصارش reaction so that it is positive for
+
+147
+00:09:55,850 --> 00:09:58,690
+the presence of antibody عشان هيك باعتبر أن الفحص
+
+148
+00:09:58,690 --> 00:10:03,700
+positive ماصارش hemolysis يعني الفحصبوزيتف الـ
+
+149
+00:10:03,700 --> 00:10:06,780
+negative test ما صارش انتجن antibody reaction أو
+
+150
+00:10:06,780 --> 00:10:10,020
+care ما صارش انتجن antibody reaction the
+
+151
+00:10:10,020 --> 00:10:13,900
+complement remains and the blood cells are lies in
+
+152
+00:10:13,900 --> 00:10:17,720
+the indicator stage so the test is negative إذا
+
+153
+00:10:17,720 --> 00:10:22,200
+صار hemolysis للـ sheep RBCs اللي أنا أضفتها معنى
+
+154
+00:10:22,200 --> 00:10:27,400
+الكلام إنه البحث negative إذا ضلت الـ sheep RBCs
+
+155
+00:10:27,400 --> 00:10:31,120
+ما صارلهاش hemolysis معنى الكلام إن البحث positive
+
+156
+00:11:24,310 --> 00:11:28,610
+الان انكمل however if there is no specific
+
+157
+00:11:28,610 --> 00:11:32,310
+antibody in the bastion serum لو كان فيش antibody
+
+158
+00:11:32,310 --> 00:11:35,090
+في ال bastion serum there will be no antigen
+
+159
+00:11:35,090 --> 00:11:37,890
+-antibody complex مش هيتكون antigen-antibody
+
+160
+00:11:37,890 --> 00:11:42,050
+complex therefore complement will be present free
+
+161
+00:11:42,050 --> 00:11:46,410
+هتظل ال complement free زي ما حكينا or unfixed in
+
+162
+00:11:46,410 --> 00:11:50,330
+the mixture يعني مش هيصيرلها fixation this unfixed
+
+163
+00:11:50,330 --> 00:11:53,760
+complement هدي ال complement اللي ضلت freeسوف
+
+164
+00:11:53,760 --> 00:11:58,060
+يتفاعل مع الـ Antibody-coded sheep RBCs اللي هو
+
+165
+00:11:58,060 --> 00:12:02,400
+الـ Indicator System اللي أنا ضفته لتحضير رقمهم
+
+166
+00:12:02,400 --> 00:12:08,880
+الـ Interpretation في الاختبار المناسب الـ
+
+167
+00:12:08,880 --> 00:12:12,520
+Available complement is fixed by antigen-antibody
+
+168
+00:12:12,520 --> 00:12:16,340
+complex and no hemolysis of sheep RBCs occurs so
+
+169
+00:12:16,340 --> 00:12:19,840
+the test is positive for presence of antibody يعني
+
+170
+00:12:19,840 --> 00:12:22,580
+إذا ماصارش hemolysis مع الكلام إن النتيجة positive
+
+171
+00:12:23,340 --> 00:12:26,580
+في تجارة الـ Negative لا يحدث تجارة الـ Antibody
+
+172
+00:12:26,580 --> 00:12:29,560
+لا يحدث تجارة الـ Antibody تجارة الـ Antibody
+
+173
+00:12:29,560 --> 00:12:34,620
+تجارة الـ Antibody
+
+174
+00:12:34,620 --> 00:12:39,520
+تجارة الـ Antibody تجارة الـ Antibody تجارة الـ
+
+175
+00:12:39,520 --> 00:12:43,580
+Antibody تجارة الـ Antibody تجارة الـ Antibody
+
+176
+00:12:43,580 --> 00:12:43,640
+تجارة الـ Antibody تجارة الـ Antibody تجارة الـ
+
+177
+00:12:43,640 --> 00:12:43,640
+Antibody تجارة الـ Antibody تجارة الـ Antibody
+
+178
+00:12:43,640 --> 00:12:43,640
+تجارة الـ Antibody تجارة الـ Antibody تجارة الـ
+
+179
+00:12:43,640 --> 00:12:44,880
+Antibody تجارة الـ Antibody تجارة الـ Antibody
+
+180
+00:12:44,880 --> 00:12:49,100
+تجارة الـ Antibody تجارة الـ Antibody تجارة الـ
+
+181
+00:12:49,100 --> 00:12:54,340
+Antibody تجارة الـ Antibody تالتي تسبب في التطور
+
+182
+00:12:54,340 --> 00:12:58,080
+إلى ألوان أمريكا الـ Controls يجب أن يتم استخدامها
+
+183
+00:12:58,080 --> 00:13:02,360
+مع ذلك فقط لتأكد أن الانتجن والسيرام ليسوا ممتعين
+
+184
+00:13:02,360 --> 00:13:06,600
+ممتعين يعني لازم أستخدم Controlات عشان أتأكد أن
+
+185
+00:13:06,600 --> 00:13:11,100
+الانتجن والسيرام اللي أنا أضفتهم مافيش اللهم ممتع
+
+186
+00:13:11,100 --> 00:13:13,880
+ممتع ممتع ممتع ممتع ممتع ممتع ممتع ممتع ممتع ممتع
+
+187
+00:13:13,880 --> 00:13:15,440
+ممتع ممتع ممتع ممتع ممتع ممتع ممتع ممتع ممتع ممتع
+
+188
+00:13:15,440 --> 00:13:22,720
+ممتع ممتع ممتع ممتع ممتع ممتع ممتع ممتالشيبرد بلد
+
+189
+00:13:22,720 --> 00:13:26,900
+سلسلة لا تتعامل بـ Autolysis يعني أنا أكون متأكدة
+
+190
+00:13:26,900 --> 00:13:30,300
+من خلال الـ control إن الخلايا هذه مارحتش عملت
+
+191
+00:13:30,300 --> 00:13:37,960
+Autolysis لحالها وتعطيني False Results الـ
+
+192
+00:13:37,960 --> 00:13:43,100
+Positive Test طبعاً هذا يعني ملخص أنتجن مع
+
+193
+00:13:43,100 --> 00:13:47,740
+Antibody from Serum مع الـ complement على 37 لساعة
+
+194
+00:13:47,740 --> 00:13:53,180
+هيعمل عندك complement fixationالخطوة التانية Fixed
+
+195
+00:13:53,180 --> 00:13:58,160
+complement زائد hemolytic system على 37 لمدة ساعة
+
+196
+00:13:58,160 --> 00:14:04,180
+no hemolysis هيعطيكي positive test negative الـ
+
+197
+00:14:04,180 --> 00:14:07,940
+complement مع الـ sheep erythrocyte طبعا هتعمل
+
+198
+00:14:07,940 --> 00:14:11,680
+complement fixation وهيصير lysis انتجن مع antibody
+
+199
+00:14:11,680 --> 00:14:15,320
+absent زائد complement هيعطيني complement not
+
+200
+00:14:15,320 --> 00:14:18,240
+fixed free complement مع الـ hemolytic system
+
+201
+00:14:18,240 --> 00:14:25,030
+هتعطيني hemolysis اللي هوnegative result بالنتائج
+
+202
+00:14:25,030 --> 00:14:30,070
+كيف بنشوفها يعني تطلعوا معايا مثلا ممكن يكون صار
+
+203
+00:14:30,070 --> 00:14:33,270
+hemolysis أو ما صار مثلا العينة الأولى ما صارش
+
+204
+00:14:33,270 --> 00:14:36,510
+فيها hemolysis إذا العينة positive التانية أو
+
+205
+00:14:36,510 --> 00:14:39,270
+التالتة أو الرابعة صار فيهم positive إذا العينة
+
+206
+00:14:39,270 --> 00:14:43,890
+negative ال hemolysis بيعرفه بتلون كل ال mixture
+
+207
+00:14:43,890 --> 00:14:49,170
+بيصير لونه pinkأول تلت أنبيب هنا أول تلتة
+
+208
+00:14:49,170 --> 00:14:52,190
+microtiter plates ماصارش فيهم hemolysis يعني
+
+209
+00:14:52,190 --> 00:14:57,890
+العينة هنا positive بينما هنا sarlysis يعني العينة
+
+210
+00:14:57,890 --> 00:15:02,890
+كانت negative طيب
+
+211
+00:15:02,890 --> 00:15:08,450
+خلينا نشوف ال reagent اللي استخدمناها أول حاجة
+
+212
+00:15:08,450 --> 00:15:12,110
+قلنا احنا في عندنا test system في عندنا indicator
+
+213
+00:15:12,110 --> 00:15:16,300
+systemالـ Test System كان عبارة عن أنتجن و
+
+214
+00:15:16,300 --> 00:15:20,420
+Antibody complement الـ Antigen ممكن يكون Soluble
+
+215
+00:15:20,420 --> 00:15:24,520
+أو Particulate الـ Antibody هو عبارة عن Human
+
+216
+00:15:24,520 --> 00:15:29,220
+Serum اللي محتوي على الـ Antibody و قد لا يكون فيه
+
+217
+00:15:29,220 --> 00:15:33,280
+Antibody الـ Complement it is a bold serum
+
+218
+00:15:33,280 --> 00:15:36,940
+obtained from four to five genepig يعني بيجيبوها
+
+219
+00:15:36,940 --> 00:15:41,380
+من الـ genepig it should be fresh or especially
+
+220
+00:15:41,380 --> 00:15:44,700
+preservedas the complement activity is heat labile
+
+221
+00:15:44,700 --> 00:15:47,540
+يعني لازم تحفظ في ظروف خاصة لأن الـ complement
+
+222
+00:15:47,540 --> 00:15:51,340
+عبارة عن heat labile component ممكن نعمل لها
+
+223
+00:15:51,340 --> 00:15:54,120
+storage على minus تلاتين في small aliquots في
+
+224
+00:15:54,120 --> 00:15:56,880
+small fraction كميات صغيرة على minus تلاتين وكل ما
+
+225
+00:15:56,880 --> 00:16:00,900
+بدي واحد كمية أخدها و أستخدمها مباشرة the
+
+226
+00:16:00,900 --> 00:16:02,800
+complement activity should be initially
+
+227
+00:16:02,800 --> 00:16:05,720
+standardized before using the test يعني لازم نعمل
+
+228
+00:16:05,720 --> 00:16:09,710
+calibration لـ ال activity بتاعة ال complementالـ
+
+229
+00:16:09,710 --> 00:16:13,950
+Indicator System فيه عندى Erythrocyte sheep RBCs
+
+230
+00:16:13,950 --> 00:16:17,930
+الـ Ampoceptor عبارة عن Hemolysin طبعا الـ
+
+231
+00:16:17,930 --> 00:16:20,710
+Antibody اللى بدى استخدمه لازم يكون عنده قدرة أنه
+
+232
+00:16:20,710 --> 00:16:25,710
+يعمل license للخلايا Hemolysin يكون طيب هذا كيف
+
+233
+00:16:25,710 --> 00:16:30,350
+بنحضره بيحقنه ال Erythrocyte بتاعة الشيب ثيرابيت
+
+234
+00:16:30,350 --> 00:16:35,950
+فبيكون Antibodies للـ RBCs طبعا تحت protocol خاص
+
+235
+00:16:36,200 --> 00:16:38,560
+وبياخدوا الـ Antibodies وهذه وبيتم استخدامها طيب،
+
+236
+00:16:38,560 --> 00:16:43,040
+إيش هي مزايا ومساوقة الـ Complement Fixation Test؟
+
+237
+00:16:43,040 --> 00:16:47,360
+أول إشي ممكن أعمل Screen لعدد كبير من البكتيريا
+
+238
+00:16:47,360 --> 00:16:51,480
+للـ Viral Infection إيه Economical، اقتصادي ورخيص
+
+239
+00:16:51,480 --> 00:16:55,840
+الـ Disadvantages، مش كتير sensitive إيه Time
+
+240
+00:16:55,840 --> 00:16:59,420
+Consuming، الـ Cross Reactivity موجودة فيه بين الـ
+
+241
+00:16:59,420 --> 00:17:02,140
+Herpes مثلا بين الـ Herpes Simplex Virus و الـ
+
+242
+00:17:02,140 --> 00:17:04,600
+Varicella Zoster يعني ممكن يصير عندي Cross
+
+243
+00:17:04,600 --> 00:17:10,110
+Reactionعطيني في واضح ال result في
+
+244
+00:17:10,110 --> 00:17:13,950
+عندنا تحوير أو modification لل compliment fixation
+
+245
+00:17:13,950 --> 00:17:17,850
+معلش أنا استعملت الرسمة تاعت compliment fixation
+
+246
+00:17:17,850 --> 00:17:20,630
+عشان أوضحها لإني مالاقيتش رسمة مناسبة على ال
+
+247
+00:17:20,630 --> 00:17:24,770
+modification هذا يعني هذه رسمة compliment fixation
+
+248
+00:17:24,770 --> 00:17:29,360
+بس أنا بدأ استخدمها للشريحةطيب الـ Modification
+
+249
+00:17:29,360 --> 00:17:32,520
+هذا اسمه Indirect Complement Fixation طبعا احنا
+
+250
+00:17:32,520 --> 00:17:35,020
+اعتمدنا الفكرة الأساسية ان الـ Antigen Antibody
+
+251
+00:17:35,020 --> 00:17:39,180
+Reaction بتاعنا اللي بيصيروا عندهم قدرة بعد ما
+
+252
+00:17:39,180 --> 00:17:41,020
+يصيروا عندهم القدرة انهم يعملوا Complement
+
+253
+00:17:41,020 --> 00:17:44,880
+Fixation هاي ال принцип الأساسي بتاعتنا لكن في ان
+
+254
+00:17:44,880 --> 00:17:48,820
+بعض الـ Serum مابقدرش يعملوا Complement Fixation
+
+255
+00:17:48,820 --> 00:17:52,920
+زي الـ Serum اللي من الدك والتركي باروت، horse،
+
+256
+00:17:52,920 --> 00:17:55,400
+cat هدول ماعندهمش القدرة انهم يعملوا Complement
+
+257
+00:17:55,400 --> 00:17:59,250
+Fixationفاحنا بدنا نتحايل على الفحص بحيث أني أعمل
+
+258
+00:17:59,250 --> 00:18:02,710
+complement fixation أو يعني أخد فكرة complement
+
+259
+00:18:02,710 --> 00:18:08,310
+fixation و أمشي الفحص طيب كيف بعمل؟ تلاقيت بعد
+
+260
+00:18:08,310 --> 00:18:14,310
+الخطوة الأولى بضيف antiserum للانتجين هذا نفسه
+
+261
+00:18:14,310 --> 00:18:18,250
+عنده القدرة أنه يعمل complement fixation تمام؟
+
+262
+00:18:18,250 --> 00:18:21,630
+بضيف antiserum عنده القدرة أنه يعمل complement
+
+263
+00:18:21,630 --> 00:18:25,740
+fixation طيب إيش رح يصير؟خلّينا نشوف الشريعة
+
+264
+00:18:25,740 --> 00:18:31,980
+دلوقتي إذا كان الـ Antibody مش موجود يعني العينة
+
+265
+00:18:31,980 --> 00:18:35,500
+negative معنى الكلام إن الـ Antigen هذا اللي ضفته
+
+266
+00:18:35,500 --> 00:18:40,960
+بالأول هيظل فيه والـ Antibody اللي أنا ضفته طبعا
+
+267
+00:18:40,960 --> 00:18:44,400
+إيش ميزته اللي أنا ضفته Antibody تاني لهذا الـ
+
+268
+00:18:44,400 --> 00:18:47,140
+Antigen لكن عنده القدرة إنه يعمل complement
+
+269
+00:18:47,140 --> 00:18:50,660
+fixation هاي الفرق بينه وبين الـ Antibody اللي كان
+
+270
+00:18:50,660 --> 00:18:53,040
+في العينة إذا كان فيه في العينة Antibody من
+
+271
+00:18:53,040 --> 00:18:57,750
+الأساس، تمام؟لذن إذا كانت العينة negative معنى
+
+272
+00:18:57,750 --> 00:19:01,390
+الكلام إن الـ antigen هذا ضال free فهيروح الـ
+
+273
+00:19:01,390 --> 00:19:04,090
+antibody اللي أنا ضفته اللي بيعمل complement
+
+274
+00:19:04,090 --> 00:19:09,050
+fixation يرتبط مع الـ antigen تمام؟ وبالتالي
+
+275
+00:19:09,050 --> 00:19:14,170
+هيتكون عندى هذا ال reaction بس لمين؟ للنتيجة الـ
+
+276
+00:19:14,170 --> 00:19:19,440
+negative مش للنتيجة الـ positive صح؟ ليش؟ لأنهالـ
+
+277
+00:19:19,440 --> 00:19:22,560
+Antigen كان Free وما ارتبطش فأنا لما أضفت الـ
+
+278
+00:19:22,560 --> 00:19:25,260
+Antibody اللي بعمل Complement Fixation ارتبط مع
+
+279
+00:19:25,260 --> 00:19:29,100
+الـ Antigen لـ Free و أعطاني Antigen Antibody
+
+280
+00:19:29,100 --> 00:19:32,460
+Reaction وعملوا Complement Fixation يعني كل الصورة
+
+281
+00:19:32,460 --> 00:19:36,380
+اللي هناك راح تنعكس بالتالي لو أضفنا الـ Sheep
+
+282
+00:19:36,380 --> 00:19:41,600
+RBCs هنا الـ Sheep RBCs في العينة الـ Negative مش
+
+283
+00:19:41,600 --> 00:19:47,920
+هتلاقي Free Complement فبالتالي مش هيصيرلها Lysis
+
+284
+00:19:48,440 --> 00:19:52,160
+لكن في العينة الـ Positive already هيكون الـ
+
+285
+00:19:52,160 --> 00:19:56,620
+Antigen مرتبط فبالتالي لما أنا أضيف الـ Antibody
+
+286
+00:19:56,620 --> 00:20:01,320
+اللي بيعمل complement fixation مش هيقدر يرتبط مع
+
+287
+00:20:01,320 --> 00:20:05,020
+الـ Antigen و بالتالي مش هيعمل complement fixation
+
+288
+00:20:05,020 --> 00:20:08,560
+و هتظل الـ complement free و لو أضفت ال indicator
+
+289
+00:20:08,560 --> 00:20:12,160
+system هتعطيني hemolysis تمام، ماعليش أنه تاني،
+
+290
+00:20:12,160 --> 00:20:14,840
+بتكرر الرسمة دي بتاعة الـ complement fixation أنا
+
+291
+00:20:14,840 --> 00:20:18,830
+استخدمتها للشريحةإذا لم يكن هناك مخلوقات موجودة في
+
+292
+00:20:18,830 --> 00:20:22,370
+الـ Test Serum فإن المخلوقات ستتفاعل مع الـ
+
+293
+00:20:22,370 --> 00:20:25,970
+Standard Anti-Serum لإصلاح الـ Complement إذا لم
+
+294
+00:20:25,970 --> 00:20:30,310
+يكن هناك مخلوقات موجودة في الفحص إذن المخلوق اللي
+
+295
+00:20:30,310 --> 00:20:33,530
+اضفته هو اللي سيتفاعل على الجانب الآخر، إذا كان
+
+296
+00:20:33,530 --> 00:20:38,050
+هناك مخلوقات موجودة في الـ Test Serum المخلوق سيتم
+
+297
+00:20:38,050 --> 00:20:41,170
+استخلاقه في المرحلة الأولى إذا كان هناك مخلوقات
+
+298
+00:20:41,170 --> 00:20:41,570
+موجودة
+
+299
+00:20:45,390 --> 00:20:48,530
+الـ Antigen هيتم استهلاكه في المرحلة الأولى يعني
+
+300
+00:20:48,530 --> 00:20:51,370
+مش هيضل عندي Antigen يتفاعل مع الـ Antibody اللي
+
+301
+00:20:51,370 --> 00:20:55,390
+بدي أضيفه So, no reaction would occur between the
+
+302
+00:20:55,390 --> 00:20:59,270
+standard antiserum and the antigen and therefore,
+
+303
+00:20:59,590 --> 00:21:03,050
+no fixation of complement would cause lysis of
+
+304
+00:21:03,050 --> 00:21:07,790
+RBCs Thus, in this case, hemolysis indicate a
+
+305
+00:21:07,790 --> 00:21:10,610
+positive result يعني عكس النتيجة الأولى تماما
+
+306
+00:21:10,610 --> 00:21:13,960
+وفهمناليش بيصير هذا الكلام؟ طيب، نيجي لـ
+
+307
+00:21:13,960 --> 00:21:20,620
+Conglutinating Complement Absorbing Test هنا نفس
+
+308
+00:21:20,620 --> 00:21:24,480
+الـ principle بتاعة الـ complement fixation لكن
+
+309
+00:21:24,480 --> 00:21:28,220
+النتيجة هنا بشوفها على شكل agglutination ما بشوفها
+
+310
+00:21:28,220 --> 00:21:33,720
+على شكل hemolysis طيب، ليش؟ هنا بستخدم complement
+
+311
+00:21:33,720 --> 00:21:37,280
+من horses الـ complement بتاعة الـ horses بتتميز
+
+312
+00:21:37,280 --> 00:21:40,520
+بإنها non-hemolyticماعندهاش القدرة على إنها تعمل
+
+313
+00:21:40,520 --> 00:21:43,740
+Hemolysis للـ RBCs هي بترتبط بالـ RBCs بس ما
+
+314
+00:21:43,740 --> 00:21:47,060
+بتعملليها Hemolysis طيب، هنا إيش ال indicator
+
+315
+00:21:47,060 --> 00:21:50,680
+system؟ ال indicator system اللي عندي هيكون RBCs
+
+316
+00:21:50,680 --> 00:21:54,780
+زي ما اتفقنا لكن بنضيف عليهم bovine serum إيش ميزة
+
+317
+00:21:54,780 --> 00:21:57,960
+ال bovine serum؟ ال bovine serum فيه beta-globulin
+
+318
+00:21:57,960 --> 00:22:02,000
+بسميه conglutinin لو كانت ال complement مرتبطة على
+
+319
+00:22:02,000 --> 00:22:07,830
+ال RBCs هيعمل agglutination للـ RBCsتمام؟ Bovine
+
+320
+00:22:07,830 --> 00:22:11,270
+serum contain a beta globulin called conglutinin
+
+321
+00:22:11,270 --> 00:22:15,510
+would also combine with a complement طبعا إذا كانت
+
+322
+00:22:15,510 --> 00:22:18,990
+ال complement مرتبطة على ال serum حيرتبط فيها أو
+
+323
+00:22:18,990 --> 00:22:24,350
+حيشتغل عليها causing agglutination conglutinating
+
+324
+00:22:24,350 --> 00:22:27,610
+of sheep red cells يعني أنتوا تذكروا معايا ال
+
+325
+00:22:27,610 --> 00:22:31,270
+system العينة ال negative هتكون ال complement فيها
+
+326
+00:22:31,270 --> 00:22:35,330
+free فبالتالي هترتبط على ال sheep RBCsوجود الـ
+
+327
+00:22:35,330 --> 00:22:38,450
+albumin الـ bovine albumin هذا راح يساعد الـ
+
+328
+00:22:38,450 --> 00:22:41,130
+complement الموجود على سطح ال RBCs بدل ما كانت
+
+329
+00:22:41,130 --> 00:22:44,030
+تعمل Hemolysis هتعمل عندى agglutination إذا الـ
+
+330
+00:22:44,030 --> 00:22:48,670
+negative result بتدل عليها وجود agglutination زي
+
+331
+00:22:48,670 --> 00:22:52,370
+ما هناك كان يدل عليها وجود Hemolysis طيب هنا عندنا
+
+332
+00:22:52,370 --> 00:22:55,530
+بعض التقنيات الأخرى اللى ممكن نسمع عنها أو نشوفها
+
+333
+00:22:55,530 --> 00:22:58,610
+في السيرولوجيا خلينا نحاول نمر عليها ك principle
+
+334
+00:22:58,610 --> 00:23:02,910
+بشكل سريعأول حاجة ما يسمى بالـ Immune Adherence
+
+335
+00:23:02,910 --> 00:23:06,510
+إيش يعني Immune Adherence؟ في عندنا بعض أنواع
+
+336
+00:23:06,510 --> 00:23:09,110
+البكتيريا زي الـ Vibrio cholera أو الـ Triponema
+
+337
+00:23:09,110 --> 00:23:14,190
+pallidium هذه بتتميز بإنه لو كان الـ Antibody
+
+338
+00:23:14,190 --> 00:23:17,590
+بتاعها موجود هيصير التفاعل، هيصير complement
+
+339
+00:23:17,590 --> 00:23:21,690
+activation إذا كان موجود في ال reaction media بعض
+
+340
+00:23:21,690 --> 00:23:25,090
+ال particles زي الارثروسيت والـ platelets راح تتوح
+
+341
+00:23:25,090 --> 00:23:28,990
+هذه البكتيريا تلتصق بالارثروسيت الموجودةهذا ما
+
+342
+00:23:28,990 --> 00:23:32,150
+يسمى بالـ Immune Adherence بمعنى لو أنا عندى عينة
+
+343
+00:23:32,150 --> 00:23:36,090
+مثلا بدي ابحث عن الـ Antibodies للـ Vibrio على
+
+344
+00:23:36,090 --> 00:23:39,450
+سبيل المثال للـ Vibrio cholera فإيش بلزمني؟ بلزمني
+
+345
+00:23:39,450 --> 00:23:43,550
+أجيب البكتيريا نفسها تمام؟ وبلزمني أجيب Complement
+
+346
+00:23:43,550 --> 00:23:49,810
+وRBCs وأخدهم ألاقيت باخد عليهم العينة إذا شفت تحت
+
+347
+00:23:49,810 --> 00:23:53,840
+الميكروسكوب لقيت أن البكتيريا التثقت بالـRBCsمعنى
+
+348
+00:23:53,840 --> 00:23:57,480
+الكلام أن العينة هذه كان فيها Antibody الـ
+
+349
+00:23:57,480 --> 00:23:59,880
+Antibody وارتباطه بالـ Antigen مع وجود الـ
+
+350
+00:23:59,880 --> 00:24:03,140
+Complement أدى لاتصاق البكتيريا بالـ Herpeses إذا
+
+351
+00:24:03,140 --> 00:24:05,940
+لاقيت البكتيريا مش ملتزقة بالـ Herpeses معنى
+
+352
+00:24:05,940 --> 00:24:08,580
+الكلام أن العينة Negative تمام؟ يعني الـ Positive
+
+353
+00:24:08,580 --> 00:24:11,780
+result معناه أنه صار أدهرة الـ Negative أنه مافيش
+
+354
+00:24:11,780 --> 00:24:14,900
+أدهرة ثانية اللي هي ال Immobilization Test قدرة
+
+355
+00:24:14,900 --> 00:24:17,940
+بعض الـ Antibodies على إيقاف حركة بعض البكتيريا
+
+356
+00:24:17,940 --> 00:24:22,720
+النشطة اللي بتتميز بأنها متحركةهنا hair antigen is
+
+357
+00:24:22,720 --> 00:24:25,000
+incubated with the patient serum يعني بجيب
+
+358
+00:24:25,000 --> 00:24:27,840
+البكتيريا بحطها مع ال patient serum في وجود ال
+
+359
+00:24:27,840 --> 00:24:31,480
+complement طبعا الآن إذا البكتيريا هذه كانت متحركة
+
+360
+00:24:31,480 --> 00:24:34,220
+وتوقفت عن الحركة معنى الكلام إن ال antibodies
+
+361
+00:24:34,220 --> 00:24:37,960
+بتاعها انوجد و أقفها عن الحركة إذا لو توقفت عن
+
+362
+00:24:37,960 --> 00:24:41,900
+الحركة إذا العينة إيش positive لو دلت تتحرك العينة
+
+363
+00:24:41,900 --> 00:24:45,260
+negative مثال عليها Ribonema Pallidium
+
+364
+00:24:45,260 --> 00:24:49,560
+Immobilization Test يعتبر هذا الفحص مهم جداوالـ
+
+365
+00:24:49,560 --> 00:24:54,080
+Gold Standard في تشخيص الـ Syphilis المسبب بقى له
+
+366
+00:24:54,080 --> 00:24:59,000
+الهيرتربونيما باليتيام طيب
+
+367
+00:24:59,000 --> 00:25:03,080
+نيجي إلى الـ Cytolytic Test هنا الـ Antibody لو
+
+368
+00:25:03,080 --> 00:25:07,720
+انوجد بعمل Lysis للبكتيرياالـ Incubation of live
+
+369
+00:25:07,720 --> 00:25:10,860
+bacterium with its specific antibody in the
+
+370
+00:25:10,860 --> 00:25:13,900
+presence of complement leads to the lyses of the
+
+371
+00:25:13,900 --> 00:25:18,000
+bacteria cell طبعا يعني إذا كان صار lyses لل
+
+372
+00:25:18,000 --> 00:25:20,840
+bacterial cells معنى الكلام أنه الـ antibody موجود
+
+373
+00:25:20,840 --> 00:25:23,580
+إذا كان ماصارش lyses معنى الكلام أنه الـ antibody
+
+374
+00:25:23,580 --> 00:25:27,520
+موجود مش موجود this is the basis of vibrocidal
+
+375
+00:25:27,520 --> 00:25:30,740
+antibody test used to measure anti cholera
+
+376
+00:25:30,740 --> 00:25:35,160
+antibodies يعني هذا بيستخدم في الـ Vibrio cholera
+
+377
+00:25:37,680 --> 00:25:41,020
+الـ Neutralization الـ Neutralization هذه تقنية
+
+378
+00:25:41,020 --> 00:25:45,600
+خليني أشوف هيك مفهومها بشكل بسيط كثير بيكون عندي
+
+379
+00:25:45,600 --> 00:25:50,960
+مثلا organism ال organism هذا معروف بتأثير معين
+
+380
+00:25:50,960 --> 00:25:55,740
+على نوع من الخلايا مثلا هذا ال organism عنده
+
+381
+00:25:55,740 --> 00:25:59,860
+القدرة أنه يعمل license للخلية تمام؟ هلأ أنا بجيب
+
+382
+00:25:59,860 --> 00:26:04,940
+عينة عشان أشوف هل ال antibody لهذا ال organism
+
+383
+00:26:04,940 --> 00:26:09,780
+موجود فيها ولا مش موجودالآن إذا أضفت الـ Serum
+
+384
+00:26:09,780 --> 00:26:14,660
+وتوقف تأثير هذا الـ organism على الخلية، بمعنى
+
+385
+00:26:14,660 --> 00:26:18,600
+الكلام إن الـ antibody بتاعه موجود وعمله
+
+386
+00:26:18,600 --> 00:26:23,000
+neutralization منع ال action بتاعه، صح؟ إذا الـ
+
+387
+00:26:23,000 --> 00:26:26,800
+procedure in which the chemical or biological
+
+388
+00:26:26,800 --> 00:26:30,400
+activity of reagent of a reagent or living
+
+389
+00:26:30,400 --> 00:26:33,440
+organism is inhibitedيعني ممكن يكون له تأثير
+
+390
+00:26:33,440 --> 00:26:36,240
+بيولوجي كيميكال إيش يعني الكيميكانية ممكن يكون
+
+391
+00:26:36,240 --> 00:26:39,700
+بيفرز مادة معينة وأنا من خلال الـ Antiserum عملت
+
+392
+00:26:39,700 --> 00:26:43,960
+neutralization لهذا الكائن أو لهذه البكتيريا وقفت
+
+393
+00:26:43,960 --> 00:26:47,020
+تكوينه لل chemical component اللي هو بيكونه مثلا
+
+394
+00:26:47,020 --> 00:26:49,740
+يعني أو تأثير معين أو تغيير في pH and so on
+
+395
+00:26:49,740 --> 00:26:54,840
+usually by a specific neutralizing antibody كيف؟
+
+396
+00:26:54,840 --> 00:27:00,010
+عن طريق antibody بيعمله neutralization في مثالفي
+
+397
+00:27:00,010 --> 00:27:02,650
+مثال شهير اللي هو الـ diphtheria toxin الـ
+
+398
+00:27:02,650 --> 00:27:07,210
+diphtheria toxin هذا معروف بإنه lethal أو dermal
+
+399
+00:27:07,210 --> 00:27:12,510
+necrotic للـ cells يعني ممكن يكسر الخلايا أو يعمل
+
+400
+00:27:12,510 --> 00:27:18,630
+لها necrosis تمام؟ فلقيت لو أنا جبت عينة لمريض بدي
+
+401
+00:27:18,630 --> 00:27:22,210
+أشوف هل المريض هذا عنده antibody للـ diphtheria
+
+402
+00:27:22,210 --> 00:27:26,770
+ولا ماعندهوش antibody بروح بضيف العينة على
+
+403
+00:27:26,770 --> 00:27:30,800
+reaction mixtureالـ Reaction Mixture إيش هيحتوي
+
+404
+00:27:30,800 --> 00:27:34,560
+على اللي هو الـ Cell Suspension الخلايا اللي
+
+405
+00:27:34,560 --> 00:27:38,920
+بيعمللها هذا الـ Toxin المفروض بيعمللها Necrosis
+
+406
+00:27:38,920 --> 00:27:43,820
+بالإضافة للـ Toxin تمام؟ إذا في عندي الـ Toxin وفي
+
+407
+00:27:43,820 --> 00:27:46,580
+عند الخلايا اللي المفروض هو بيعمللها Necrosis
+
+408
+00:27:46,580 --> 00:27:50,680
+فأضفت عليهم العينة بتاعي الآن إذا اتوقفت الـ
+
+409
+00:27:50,680 --> 00:27:53,960
+Necrosis معنى الكلام إن العينة فيها Antibody للـ
+
+410
+00:27:53,960 --> 00:27:58,930
+Toxin عملّه Neutralization و Blockوقف تأثيره على
+
+411
+00:27:58,930 --> 00:28:03,550
+الخلية فضلت الخلية كويسة لكن لو ضلت عملية الـ
+
+412
+00:28:03,550 --> 00:28:07,430
+Necrosis معنى الكلام إن الـ Antibody مش موجود في
+
+413
+00:28:07,430 --> 00:28:11,070
+عينة الـ Serum بمعنى إن العينة Negative وبالتالي
+
+414
+00:28:11,070 --> 00:28:15,490
+ضل التوكسين يشتغل زي ما هو ويعمل Necrosis للخلايا
+
+415
+00:28:15,490 --> 00:28:18,990
+8 مرة نقرأها As an example, the lethal or
+
+416
+00:28:18,990 --> 00:28:22,150
+thermionicotic action of the stereotoxin on animal
+
+417
+00:28:22,550 --> 00:28:26,370
+may be completely neutralized by an equivalent
+
+418
+00:28:26,370 --> 00:28:30,010
+amount of diphtheria antitoxin يعني لو نوجد الـ
+
+419
+00:28:30,010 --> 00:28:34,730
+antitoxin في العينة هيصير لهذا الـ toxin a
+
+420
+00:28:34,730 --> 00:28:38,530
+neutralization an antibody produced in animal or
+
+421
+00:28:38,530 --> 00:28:42,050
+in human after contact with diphtheria toxin or
+
+422
+00:28:42,050 --> 00:28:46,430
+toxoid تمام هك؟ يعني الـ antibody بعمل
+
+423
+00:28:46,430 --> 00:28:50,010
+neutralization للـ toxin طب كيف بده أشوف؟هل الـ
+
+424
+00:28:50,010 --> 00:28:54,010
+Toxin ضايل بيعمل التأثير بتاعه ولا لأ؟ إذا بطل
+
+425
+00:28:54,010 --> 00:28:56,630
+يعمل التأثير بتاعه إذن الـ Antibody عمله
+
+426
+00:28:56,630 --> 00:28:59,670
+Neutralization إذا بطل يعمل التأثير بتاعه معناه
+
+427
+00:28:59,670 --> 00:29:01,230
+الكلام إن الـ Antibody مش موجود
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/8BQh-SbCWXM.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/8BQh-SbCWXM.srt
new file mode 100644
index 0000000000000000000000000000000000000000..a2763a1537ba917a0b994c60d1b691afb10c6714
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/8BQh-SbCWXM.srt
@@ -0,0 +1,1388 @@
+1
+00:00:01,850 --> 00:00:06,230
+بسم الله الرحمن الرحيم اليوم إن شاء الله رب
+
+2
+00:00:06,230 --> 00:00:10,470
+العالمين راح ناخد أول تطبيق على موضوع ال
+
+3
+00:00:10,470 --> 00:00:14,830
+agglutination. طبعا هو الشغل العملي اللي هيكون
+
+4
+00:00:14,830 --> 00:00:17,570
+على agglutination. هناخد تطبيقات كتير على ال
+
+5
+00:00:17,570 --> 00:00:21,790
+agglutination. أول واحد هيكون rheumatoid factor
+
+6
+00:00:21,790 --> 00:00:27,630
+اختصاره RF. أول
+
+7
+00:00:27,630 --> 00:00:30,970
+قبل ما نحكي عن الـ rheumatoid factor، بدنا نشوف مع
+
+8
+00:00:30,970 --> 00:00:35,320
+بعض إيش هو الـ Rheumatoid Arthritis اللي بتتم
+
+9
+00:00:35,320 --> 00:00:39,580
+تشخيصه من خلال الـ Rheumatoid Factor. Rheumatoid
+
+10
+00:00:39,580 --> 00:00:44,640
+Arthritis عبارة عن Chronic Autoimmune Inflammatory
+
+11
+00:00:44,640 --> 00:00:50,320
+Disorder، عبارة عن Autoimmune Disease بيأثر بشكل
+
+12
+00:00:50,320 --> 00:00:58,680
+أساسي على مفاصل الـ hands، الـ feet، و other areas in
+
+13
+00:00:58,680 --> 00:01:02,080
+the body. As the disease progresses، يعني كل ما تطور
+
+14
+00:01:02,080 --> 00:01:08,220
+المرض، هتلاقي أنه مناطق تانية بدأت تتأثر في الجسم، الـ
+
+15
+00:01:08,220 --> 00:01:11,940
+disease affects the lining of the joints. بيأثر على
+
+16
+00:01:11,940 --> 00:01:17,480
+البطانة أو الـ epithelium المبطّن للمفصل، مما يؤدي
+
+17
+00:01:17,480 --> 00:01:22,260
+إلى حدوث swelling and pain and inflammatory
+
+18
+00:01:22,260 --> 00:01:24,520
+symptoms.
+
+19
+00:01:26,260 --> 00:01:31,920
+طبعاً هذا مع الوقت بيؤدي to bone erosion. إيش يعني
+
+20
+00:01:31,920 --> 00:01:36,040
+bone erosion؟ تآكل في العظام وذوبان.  Joint
+
+21
+00:01:36,040 --> 00:01:40,980
+deformity. مع الوقت بيسبب، بالإضافة لتآكل العظام، أو
+
+22
+00:01:40,980 --> 00:01:44,980
+سبب، يعني تآكل العظام يؤدي إلى تشوهات في المفصل.
+
+23
+00:01:44,980 --> 00:01:49,960
+أكثر المناطق اللي ممكن تتأثر بـ Rheumatoid
+
+24
+00:01:49,960 --> 00:01:55,100
+Arthritis اللي هي الـ tendons، heart valves، vessels،
+
+25
+00:01:55,740 --> 00:02:00,480
+heart، blood vessels، subcutaneous tissue، الـ lungs،
+
+26
+00:02:00,480 --> 00:02:03,920
+يعني كل هذه الأماكن ممكن يصير فيها inflammation
+
+27
+00:02:03,920 --> 00:02:13,120
+وتتأثر بالـ rheumatoid arthritis. Rheumatoid
+
+28
+00:02:13,120 --> 00:02:18,020
+arthritis هو عبارة عن autoimmune disorder. إيش يعني
+
+29
+00:02:18,020 --> 00:02:22,010
+autoimmune disorder؟ طبعاً إحنا عارفين إنه جهاز
+
+30
+00:02:22,010 --> 00:02:25,130
+المناعة عنده القدرة على إنه يميز الـ "self" عن الـ
+
+31
+00:02:25,130 --> 00:02:31,610
+"non-self". في لحظة معينة بيفقد جهاز المناعة هذه
+
+32
+00:02:31,610 --> 00:02:36,750
+القدرة، وبصير يتعامل مع الـ "self-antigen" على إنها
+
+33
+00:02:36,750 --> 00:02:40,410
+"foreign antigen"، وبيبلش يكون لها antibodies
+
+34
+00:02:40,410 --> 00:02:44,610
+وبيهاجمها. طبعاً هذا بيؤدي لـ "inflammation".
+
+35
+00:02:44,610 --> 00:02:46,670
+"inflammation" وين بيكون؟ إحنا لو تخيلنا، ما هي
+
+36
+00:02:46,670 --> 00:02:52,150
+المفصل؟ المفصل فيه عندي  Synovium. المفصل نفسه مغطى
+
+37
+00:02:52,150 --> 00:02:56,030
+بـ Cartilage، فيه بعد الـ Cartilage، Synovial membrane،
+
+38
+00:02:56,030 --> 00:03:00,270
+وبين العظمتين تبع المفصل، فيه عندي الـ Synovial
+
+39
+00:03:00,270 --> 00:03:03,090
+Fluid. فالـ EDD، هيبلش يصير Inflammation في
+
+40
+00:03:03,090 --> 00:03:06,190
+الـ Synovial membrane المحيط بهذه الـ Synovial
+
+41
+00:03:06,190 --> 00:03:09,290
+Cavity. الالتهاب اللي في الـ Synovial membrane هذا
+
+42
+00:03:09,290 --> 00:03:15,000
+طبعاً راح يعمل تراكم للسوائل بكمية كبيرة، وطبعاً
+
+43
+00:03:15,000 --> 00:03:19,740
+inflammation من ناحية pain، و hotness، و redness، و swelling،
+
+44
+00:03:19,740 --> 00:03:23,760
+وعدم القدرة على تحريك المفصل. بعد ذلك طبعاً، زي ما
+
+45
+00:03:23,760 --> 00:03:27,540
+قلت لكم، مع الوقت بيبدأ يصير تآكل في العظام وتشوهات
+
+46
+00:03:27,540 --> 00:03:32,800
+في المفصل. الـ Rheumatoid Arthritis يعتبر systemic
+
+47
+00:03:32,800 --> 00:03:37,700
+disease، يعني ما بيأثر بس على المفاصل. هلقيت الـ
+
+48
+00:03:37,700 --> 00:03:42,090
+autoimmune diseases، إحنا بنقسمها لنوعين. النوع
+
+49
+00:03:42,090 --> 00:03:45,850
+اللي بيسمّوه Systemic Autoimmune Disease، يعني ممكن يأثر
+
+50
+00:03:45,850 --> 00:03:51,070
+على أماكن كثيرة من الجسم. الـ نوع الثاني،
+
+51
+00:03:51,070 --> 00:03:57,970
+Localized أو Non-Systemic. النوع الثاني بيأثر على
+
+52
+00:03:57,970 --> 00:04:03,550
+organ معيّن، على خلية نوع معيّن من الخلايا، على نسيج
+
+53
+00:04:03,550 --> 00:04:08,150
+معيّن. لكن Rheumatoid Arthritis بيأثر على كل الجسم.
+
+54
+00:04:08,150 --> 00:04:10,870
+كل الجسم ممكن يتأثر، ويصير فيه مضاعفات.
+
+55
+00:04:15,650 --> 00:04:21,070
+طيب، نيجي للتغيرات اللي ممكن تصير خلال الـ
+
+56
+00:04:21,070 --> 00:04:25,670
+Rheumatoid Arthritis. بداية، Formation of Granulation
+
+57
+00:04:25,670 --> 00:04:31,090
+Tissue that extends as a vascular layer from the
+
+58
+00:04:31,090 --> 00:04:35,030
+margin towards the center of the affected joint.
+
+59
+00:04:35,030 --> 00:04:41,230
+إيش يعني؟ بيبدأ يصير Granulation Tissue، نسيج عامل
+
+60
+00:04:41,230 --> 00:04:48,560
+Granulation. وهذا النسيج يمتد من أطراف المفصل، أو
+
+61
+00:04:48,560 --> 00:04:53,000
+الأطراف، المنطقة الملتهبة في المفصل، ويمتد إلى الوسط.
+
+62
+00:04:53,000 --> 00:04:57,080
+فبتلاقي المنطقة اللي في منطقة المفصل كلها بيبلش
+
+63
+00:04:57,080 --> 00:05:00,900
+يصير فيها Granulation tissue. الشغل الثاني،
+
+64
+00:05:00,900 --> 00:05:05,960
+Generalized lymphadenopathy، تورّم في الغدد
+
+65
+00:05:05,960 --> 00:05:10,220
+اللمفاوية بشكل عام في الجسم.  Bacteremia. طيب، إيش
+
+66
+00:05:10,220 --> 00:05:15,490
+الأعراض المصاحبة للـ Rheumatoid Arthritis؟ أول حاجة،
+
+67
+00:05:15,490 --> 00:05:22,690
+pain، بيبدأ يشكي المريض من ألم في المفاصل، سخونة
+
+68
+00:05:22,690 --> 00:05:28,530
+في المفصل، warmth، swelling، انتفاخ، morning stiffness،
+
+69
+00:05:28,530 --> 00:05:33,730
+في المفصل،  صبح المفصل مش قادر يحركه، nodule under
+
+70
+00:05:33,730 --> 00:05:38,410
+the skin، بتلاقي زي حبيبات تحت الجلد. If the disease
+
+71
+00:05:38,410 --> 00:05:44,220
+has progressed، لو المرض تطور، هتلاقي في الـ X-ray،
+
+72
+00:05:44,220 --> 00:05:47,700
+swollen joint capsule and loss of cartilage and
+
+73
+00:05:47,700 --> 00:05:52,040
+bone. هتلاقي إنه المفصل صار فيه انتفاخ، والـ
+
+74
+00:05:52,040 --> 00:05:55,060
+cartilage بلش يصير فيها تآكل، بالإضافة لإنه كمان
+
+75
+00:05:55,060 --> 00:06:03,500
+البون هيصير فيها تآكل. نيجي
+
+76
+00:06:03,500 --> 00:06:08,030
+الآن للـ diagnosis of rheumatoid arthritis.  الصحيح
+
+77
+00:06:08,030 --> 00:06:13,050
+أن روماتويد أرثرايتس يعتبر من الأمراض المعقدة من
+
+78
+00:06:13,050 --> 00:06:17,030
+ناحية الـ diagnosis، يعني مافي عندي فحص بحد ذاته
+
+79
+00:06:17,030 --> 00:06:19,910
+أقدر أقول إن هذا الفحص positive، معناه الكلام إن
+
+80
+00:06:19,910 --> 00:06:23,970
+هذا مريض روماتويد أرثرايتس. هذا negative، يعني لأ،
+
+81
+00:06:23,970 --> 00:06:26,290
+يعني حتى الـ Rheumatoid factor اللي إحنا بدنا
+
+82
+00:06:26,290 --> 00:06:32,370
+ناخذه اليوم، نسبة الدقة فيه 60%، يعني في عندي 40% من
+
+83
+00:06:32,370 --> 00:06:34,590
+الناس هيطلع عندهم إما false positive أو false
+
+84
+00:06:34,590 --> 00:06:39,020
+negative result. عشان هيك، بيعتبر هذا الفحص، يعني، أو
+
+85
+00:06:39,020 --> 00:06:44,820
+عفوًا، هذا المرض بيتم تشخيصه عن طريق مجموعة من
+
+86
+00:06:44,820 --> 00:06:48,580
+الأشياء مع بعض، يعني مجتمعة مع بعض. في عندي
+
+87
+00:06:48,580 --> 00:06:52,360
+Clinical Diagnosis، في عندي Lab Diagnosis، Imaging
+
+88
+00:06:52,360 --> 00:06:57,320
+Features، بالتصوير، كل الأشياء هذه مع بعض بتخلي
+
+89
+00:06:57,320 --> 00:07:01,140
+الدكتور يكوّن صورة متكاملة، ويقدر يعطي Diagnosis
+
+90
+00:07:01,140 --> 00:07:03,380
+لـ Rheumatoid Arthritis. بس يعني، لو قلت Lab
+
+91
+00:07:03,380 --> 00:07:06,240
+Diagnosis لحاله ما بيتكفيش، Clinical Features ما
+
+92
+00:07:06,240 --> 00:07:10,260
+بيتكفيش، and so on. لذا، نبدأ فيهم واحدة واحدة. أول
+
+93
+00:07:10,260 --> 00:07:14,940
+واحدة، الـ Lab Diagnosis. الـ Lab Diagnosis، هنلاقي
+
+94
+00:07:14,940 --> 00:07:19,240
+عند مريض الـ Rheumatoid Arthritis، الـ ESR مرتفع.
+
+95
+00:07:19,240 --> 00:07:23,960
+الـ Erythrocyte sedimentation rate مرتفع، هاي حاجة
+
+96
+00:07:23,960 --> 00:07:28,820
+من الحاجات. الـ CRP، يعني في الموضوع الجاي هيكون الـ CRP، راح
+
+97
+00:07:28,820 --> 00:07:32,520
+ناخذه. هذا بيرتفع في الـ inflammation، البروتين بيرتفع
+
+98
+00:07:32,520 --> 00:07:35,840
+في حالة الـ inflammation، الـ acute inflammation. CRP
+
+99
+00:07:35,840 --> 00:07:42,460
+برضه هنلاقيه مرتفع. هنعمل  Rheumatoid factor،
+
+100
+00:07:42,460 --> 00:07:45,780
+هتلاقيه مرتفع، هتلاقي الـ تيتراعه فوق
+
+101
+00:07:45,780 --> 00:07:50,460
+الثمانية. Anti-nuclear antibody، ممكن يكون عنده
+
+102
+00:07:50,460 --> 00:07:54,580
+positive أحياناً. Anti-cyclic citrullinated peptide،
+
+103
+00:07:54,580 --> 00:07:59,990
+و Anti-mutated citrullinated-vimentin.  أهم واحد،
+
+104
+00:07:59,990 --> 00:08:03,070
+يعني أفضل واحد في الفحوصات المخبرية للـ Rheumatoid
+
+105
+00:08:03,070 --> 00:08:07,230
+Arthritis اللي هو الـ Anti-cyclic Citrullinated
+
+106
+00:08:07,230 --> 00:08:11,690
+Peptide. اليوم هو يعتبر فحص حديث، وبيعطي Diagnosis
+
+107
+00:08:11,690 --> 00:08:16,730
+جيد للـ Rheumatoid Arthritis. لذا، هذه مجموعة الـ lab
+
+108
+00:08:16,730 --> 00:08:21,670
+tests اللي بتنعمل لمريض Rheumatoid Arthritis. نيجي
+
+109
+00:08:21,670 --> 00:08:27,000
+للأشياء الثانية. نأتي للـ Image، زي الـ ultrasound،
+
+110
+00:08:27,000 --> 00:08:31,440
+والراديوجرافي، والأشياء هذه. نشوف إيش بينعمل. أول شيء
+
+111
+00:08:31,440 --> 00:08:35,440
+اللي هي الـ Radiography. Radiography اللي هي صورة
+
+112
+00:08:35,440 --> 00:08:39,460
+أشعة، بيقولوا عليها ملونة. بيحطوا فيها مادة مشعة، بتصور
+
+113
+00:08:39,460 --> 00:08:44,360
+المفصل. في الـ X-Ray بتعطي شوية تفاصيل، فبتبين تفاصيل
+
+114
+00:08:44,360 --> 00:08:47,740
+المفصل. تعتبر الـ First Choice، ممكن يصوروا فيها
+
+115
+00:08:47,740 --> 00:08:50,800
+المفاصل كلها بشكل عام، الإيدين، الـ rest اللي فيه
+
+116
+00:08:50,800 --> 00:08:55,200
+تغيير، أي منطقة ممكن تتصوّر بهذه التقنية. الشغلة
+
+117
+00:08:55,200 --> 00:08:59,220
+الثانية اللي هي الـ MRI. الـ MRI اللي هي الـ
+
+118
+00:08:59,220 --> 00:09:02,390
+Magnetic Resonance Imaging. الرنين المغناطيسي، اللي
+
+119
+00:09:02,390 --> 00:09:06,650
+إحنا بنسمّيه بشكل عام للـ cervical spine، العظام
+
+120
+00:09:06,650 --> 00:09:13,350
+العمود الفقري من جهة الـ cervical region. بيبين إن
+
+121
+00:09:13,350 --> 00:09:18,160
+فيه التهاب وفيه تآكل. Ultrasound. Ultrasound طبعاً
+
+122
+00:09:18,160 --> 00:09:21,680
+بتبين عندي هذه، يعني بأخذ فكرة عن المفصل. بياخد
+
+123
+00:09:21,680 --> 00:09:26,200
+الدكتور فكرة عن الـ Tendon Sheath، عن التغيرات
+
+124
+00:09:26,200 --> 00:09:29,780
+اللي صارت في المفصل، درجة الـ Vascularization of
+
+125
+00:09:29,780 --> 00:09:32,860
+the synovial membrane، and even erosion، يعني حتى
+
+126
+00:09:32,860 --> 00:09:36,980
+التآكل ممكن يبين بالـ Ultrasound. الشغلة الأخيرة ممكن
+
+127
+00:09:36,980 --> 00:09:40,920
+نعملها، اللي هي الـ Joint Aspiration. هذا في حالة ما
+
+128
+00:09:40,920 --> 00:09:44,800
+يكون فيه accumulation للسوائل. ممكن ياخدوا عينة من
+
+129
+00:09:44,800 --> 00:09:47,520
+الـ Synovial Fluid نفسه، ويعملوا عليها Gram
+
+130
+00:09:47,520 --> 00:09:51,120
+Stain، Cell Count، و Culture. بعدين Assessment of
+
+131
+00:09:51,120 --> 00:09:54,340
+Overall Appearance للـ patient. هذه الأشياء كلها
+
+132
+00:09:54,340 --> 00:09:57,760
+بيعملها الدكتور عشان يعطي في الآخر Diagnosis للـ
+
+133
+00:09:57,760 --> 00:10:06,360
+Rheumatoid Arthritis. طيب،
+
+134
+00:10:06,360 --> 00:10:09,620
+نيجي للجزئية تبع الـ Rheumatoid Factor. إيش هو الـ
+
+135
+00:10:09,620 --> 00:10:14,480
+Rheumatoid Factor؟ الـ Rheumatoid Factor غالباً
+
+136
+00:10:14,480 --> 00:10:20,300
+بنلاقيه في حالات Rheumatoid Arthritis. هو عبارة عن
+
+137
+00:10:20,300 --> 00:10:25,280
+إيش؟ هو عبارة عن Antibody. Antibody لإيش؟ خليكم
+
+138
+00:10:25,280 --> 00:10:31,360
+معايا هنا. الـ Rheumatoid Factor، هذا الـ IgM اللي
+
+139
+00:10:31,360 --> 00:10:40,260
+بالصورة، أو هذا الـ IgG، هو عبارة عن Antibody، يتكوّن
+
+140
+00:10:40,260 --> 00:10:47,640
+في الجسم، للـ FC portion بتاعة الـ IgG. ثمانية مرات هو
+
+141
+00:10:47,640 --> 00:10:52,160
+عبارة عن Antibody، يتكوّن للـ FC portion بتاعة الـ
+
+142
+00:10:52,160 --> 00:10:58,340
+IgG الموجودة في الجسم. قد يكون من النوع IgM أو IgG.
+
+143
+00:10:58,340 --> 00:11:04,020
+طيب، لما بتكون Antibody لـ Antibody، هيعملوا اتنين
+
+144
+00:11:04,020 --> 00:11:11,150
+Complexes مع بعض، وبيبدو يترسبوا في المفاصل. الترسّب
+
+145
+00:11:11,150 --> 00:11:15,370
+هذا في المفاصل، هيعمل activation للـ complement،
+
+146
+00:11:15,370 --> 00:11:21,230
+وهيعمل عندي type 3 hypersensitivity reaction، ويؤدي
+
+147
+00:11:21,230 --> 00:11:25,150
+لـ inflammation. يعني immune complexes اترسبت، هتعمل
+
+148
+00:11:25,150 --> 00:11:28,770
+complement activation، واتنشرت في جهاز المناعة، إنه
+
+149
+00:11:28,770 --> 00:11:31,870
+يبدأ يشتغل، ويعمل الـ signs المعروفة بتاعة الـ
+
+150
+00:11:31,870 --> 00:11:35,530
+inflammation، اللي هي التورم، والاحمرار، والألم،
+
+151
+00:11:35,530 --> 00:11:40,530
+والأعراض المصاحبة للـ rheumatoid arthritis. أُعيد
+
+152
+00:11:40,530 --> 00:11:45,710
+ثاني. إذا هو Antibody للـ FC portion بتاعت الـ IgG،
+
+153
+00:11:45,710 --> 00:11:49,270
+Antibody لـ Antibody الموجودة في الجسم، بيعمل immune
+
+154
+00:11:49,270 --> 00:11:53,510
+complexes، بتترسب في المفصل، وبتكون harmful للمفصل،
+
+155
+00:11:53,510 --> 00:12:00,890
+بتكون مؤذية وضارة. طيب، نيجي للفحص بتاع الـ
+
+156
+00:12:00,890 --> 00:12:03,930
+Rheumatoid Factor. The test for rheumatoid factor
+
+157
+00:12:03,930 --> 00:12:06,870
+may be ordered when a person has signs and
+
+158
+00:12:06,870 --> 00:12:10,310
+symptoms of rheumatoid arthritis. يعني، الدكتور
+
+159
+00:12:10,310 --> 00:12:13,870
+أول ما واحد بيروح يشكي من الوجع في المفاصل، من
+
+160
+00:12:13,870 --> 00:12:18,470
+الحاجات اللي بيعملوها عادة، بيطلبه CBC، و ESR،
+
+161
+00:12:18,470 --> 00:12:23,810
+بيطلبه RF، و CRB، و Uric Acid. هذه الحاجات، يعني،
+
+162
+00:12:23,810 --> 00:12:27,850
+بيشكوا أنه مثلاً يكون فيه Gout، فيه Uric Acid مرتفع
+
+163
+00:12:27,850 --> 00:12:31,370
+في المفاصل. بيعملوا روماتويد، وبيطلبوا الـ ASOT. راح
+
+164
+00:12:31,370 --> 00:12:35,410
+ناخذه لقدام شوية. يعني، هم بيدرّجوا حسب الأعراض، بيرجّحوا
+
+165
+00:12:35,410 --> 00:12:39,620
+مين يطلب قبل الثاني. إذن، من الفحوصات اللي بتُطلب،
+
+166
+00:12:39,620 --> 00:12:43,840
+بنقول الـ RF. بقول لك
+
+167
+00:12:43,840 --> 00:12:47,620
+إنّه لو طلع معاك الـ RF Negative، لكن أعراض الـ
+
+168
+00:12:47,620 --> 00:12:51,400
+Rheumatoid Arthritis موجودة، ممكن ينطلب، يعني، بقي
+
+169
+00:12:51,400 --> 00:12:54,960
+ممكن يكون الـ titer تاعه واطي، وبعد فترة يرتفع،
+
+170
+00:12:54,960 --> 00:12:59,120
+فممكن الدكتور يطلبه بعد فترة كمان مرة. إذن، لو طلع
+
+171
+00:12:59,120 --> 00:13:02,200
+معايا Negative في المرة الأولى، مع استمرار الأعراض،
+
+172
+00:13:02,200 --> 00:13:06,880
+بنعيد الـ Rheumatoid Factor. وغالباً، يعني إذا في
+
+173
+00:13:06,880 --> 00:13:12,200
+روماتويد أرثرايتس، ممكن يرجع يعطيني Positive. في
+
+174
+00:13:12,200 --> 00:13:16,680
+عندي Anti-cyclic Citrullinated Peptide. هذه برضه ممتازة
+
+175
+00:13:16,680 --> 00:13:19,360
+في الـ Diagnosis. هناخد عنها كمان شوية بالتفصيل.
+
+176
+00:13:19,360 --> 00:13:24,760
+
+223
+00:16:53,390 --> 00:16:58,270
+العينة اللي أنا باخدها Serum لا يجوز بأي حال من
+
+224
+00:16:58,270 --> 00:17:01,570
+الأحوال أني أخد بلازمة لأن البلازمة فيها
+
+225
+00:17:01,570 --> 00:17:05,930
+Fibrinogen، والـFibrinogen for sure هيعطيني مع
+
+226
+00:17:05,930 --> 00:17:09,630
+الـRheumatoid Factor Positive، عشان هيك منفعش أخد
+
+227
+00:17:09,630 --> 00:17:13,870
+بلازما خالص، باخد Serum أو synovial fluid sample
+
+228
+00:17:13,870 --> 00:17:22,210
+الآن كيف طريقة الفحص هذا؟ بعمله في عندي slide، slide
+
+229
+00:17:22,210 --> 00:17:26,910
+هذه، يعني بختارها إما سودة أو بيضاء حسب لون الـ
+
+230
+00:17:26,910 --> 00:17:30,330
+Reagent، إذا كان الـReagent أبيض بختار خلفية سوداء،
+
+231
+00:17:30,750 --> 00:17:33,910
+إذا كان الـReagent أزرق أو أي لون ثاني بختار
+
+232
+00:17:33,910 --> 00:17:37,450
+خلفية بيضاء، عشان هي خلفية تساعد على، يعني بختار
+
+233
+00:17:37,450 --> 00:17:41,950
+خلفية مساعدة معاكسة للون، تساعدني على أني أشوف الـ
+
+234
+00:17:41,950 --> 00:17:46,670
+Agglutination، باخد directly one drop من الـsample
+
+235
+00:17:46,670 --> 00:17:49,290
+على one drop من الـReagent، طبعاً الـdrop في
+
+236
+00:17:49,290 --> 00:17:52,330
+السيرولوجي خدوها قاعدة، لما أقولك one drop، one drop
+
+237
+00:17:52,330 --> 00:17:55,970
+الـdrop عبارة عن خمسين microliter، هذه خديها
+
+238
+00:17:55,970 --> 00:18:00,970
+القاعدة، باخد one drop مع one drop، بعمل mixing وبشوف
+
+239
+00:18:00,970 --> 00:18:04,850
+النتيجة، طبعاً إذا ظهر Agglutination يعني Positive،
+
+240
+00:18:04,850 --> 00:18:11,370
+إذا ما ظهر Agglutination يعني إيش؟ Negative، طيب
+
+241
+00:18:11,370 --> 00:18:18,650
+هنا في عندي ملاحظة مهمة، في الشغل القديم في الـ
+
+242
+00:18:18,650 --> 00:18:23,050
+Rheumatoid Factor، لو أنا أجيت عملت أول واحدة وطلعت
+
+243
+00:18:23,050 --> 00:18:28,260
+معايا Positive، الـ titer تاعها هيكون واحد، طبعاً هذه
+
+244
+00:18:28,260 --> 00:18:32,720
+ما بعتبرهاش Positive، لازم يكون الـ titer أكثر من 8،
+
+245
+00:18:32,720 --> 00:18:37,440
+عشان أعتبرها Positive، فإيش أنا بروح بعمل؟ لازم أعمل
+
+246
+00:18:37,440 --> 00:18:40,660
+منها Serial Dilution، يعني باخد من العينة يا بنات
+
+247
+00:18:40,660 --> 00:18:49,100
+في تيوب بعمل Serial Dilution 1 لـ 2، 1 لـ 4، 1 لـ 8، 1 لـ
+
+248
+00:18:49,100 --> 00:18:54,460
+16 أو 1 لـ 32، يعني قد صار عندي مثلاً خمسة كيوبات، أنا
+
+249
+00:18:54,460 --> 00:18:56,580
+عاملة فيهم Serial Dilution، بطريقة الـSerial
+
+250
+00:18:56,580 --> 00:18:59,260
+Dilution اللي حكينا عنها في الأسبوع الماضي، هدول في
+
+251
+00:18:59,260 --> 00:19:02,580
+قنابيب، هك و هحطهم على الراك و بعمل لهم Dilution بس
+
+252
+00:19:02,580 --> 00:19:06,080
+يرقاق، أخد من أول واحدة اللي هي 1 لـ 2، أخد منها
+
+253
+00:19:06,080 --> 00:19:09,800
+خمسين ميكرون أحط على الـ slide هذه، وأحط عليها
+
+254
+00:19:09,800 --> 00:19:13,820
+خمسين ميكرون من الـ Reagent، وأعمل Mixing وأشوف
+
+255
+00:19:13,940 --> 00:19:17,400
+إذا كانت Positive بدي أعمل اللي بعدها بنفس الطريقة،
+
+256
+00:19:17,400 --> 00:19:22,180
+50 ميكرون من الـ tube اللي تركيزها 1 لـ 4، على 50
+
+257
+00:19:22,180 --> 00:19:25,800
+ميكرون من الـ Reagent، لغاية ما تعطيني Negative،
+
+258
+00:19:25,800 --> 00:19:31,980
+أضلني أعمل لغاية ما تعطيني Negative، الآن بعتبرها
+
+259
+00:19:31,980 --> 00:19:37,520
+Positive، بعتبرها Positive إذا الـ titer زاد عن 8،
+
+260
+00:19:37,520 --> 00:19:43,330
+لغاية 8 فما فوق بعتبرها Positive، أقل من 8 بعتبرهاش
+
+261
+00:19:43,330 --> 00:19:46,870
+Positive، يعني بيبقى False Positive، تمام يا بنات؟
+
+262
+00:19:46,870 --> 00:19:52,530
+إذا الـ titer لازم ينعمل في الفحصات السيرولوجية،
+
+263
+00:19:52,530 --> 00:19:56,390
+عنا هنا في الـ synovial fluid، في الـ Rheumatoid Factor،
+
+264
+00:19:56,390 --> 00:20:00,530
+لازم الـ titer أعمله ويزيد عن 8 عشان أعتبر إن
+
+265
+00:20:00,530 --> 00:20:04,630
+النتيجة Positive، لو طلعت عندي مثلاً الـ titer 8،
+
+266
+00:20:04,630 --> 00:20:10,920
+يندي طريقتين للتعبير عن النتيجة، إما بقول 8، الـ
+
+267
+00:20:10,920 --> 00:20:15,800
+titer 8، أو بعبر عنه بالـ units per milliliter، طيب
+
+268
+00:20:15,800 --> 00:20:21,460
+كيف أحول الـ titer إلى units per milliliter؟ في
+
+269
+00:20:21,460 --> 00:20:26,160
+رقم بيكون معطيني إياه في الـ kit، الرقم هذا هو عبارة
+
+270
+00:20:26,160 --> 00:20:29,720
+عن تركيز الـ Positive Control، ممكن يقول 6 مثلاً،
+
+271
+00:20:29,720 --> 00:20:36,180
+فإذا قال 6، بقول لو طلع عندي الـ titer 8، بضرب 8 في
+
+272
+00:20:36,180 --> 00:20:43,480
+6، بطلع عندي التركيز unit per milliliter، 6 × 8 = 48، واضح؟
+
+273
+00:20:43,480 --> 00:20:46,980
+إذا في عندي طريقتين للتعبير عن النتيجة، إما بالـ
+
+274
+00:20:46,980 --> 00:20:51,580
+titer وإما بالـ unit، فبكيد بدي أحول من titer لـ unit،
+
+275
+00:20:51,580 --> 00:20:57,220
+بضرب في رقم، هذا الرقم بيكون معطيني إياه الـ kit، هو
+
+276
+00:20:57,220 --> 00:21:01,940
+عبارة عن إيش؟ تركيز الـ Positive Control، مثلاً كان
+
+277
+00:21:01,940 --> 00:21:10,550
+كاتب عليه 6، فبدي أضرب في 6، 6 × 8 = 48 unit per milliliter،
+
+278
+00:21:10,550 --> 00:21:14,430
+إن شاء الله يعني بتتاح الظروف وبنرجع وهذا الشغل
+
+279
+00:21:14,430 --> 00:21:18,310
+كله بنشتغله وبنشوف كيف بنعمل الـ Serial Dilution،
+
+280
+00:21:18,310 --> 00:21:24,630
+وكيف بنشتغل هذا على أرض الواقع، اللي حكينا عنه قبل
+
+281
+00:21:24,630 --> 00:21:30,190
+بشوية، أن الفحص كان بيعتمد الـ Antigen أو الـ
+
+282
+00:21:30,190 --> 00:21:32,650
+Antibody، اللي حكينا عنه، Antibody، وأحياناً تتعاملوا
+
+283
+00:21:32,650 --> 00:21:36,960
+معاه كـ Antigen محمل على Latex Particles، لكن في
+
+284
+00:21:36,960 --> 00:21:41,460
+طريقة ثانية، إن نحمل الـ Antibody هذا على surface of
+
+285
+00:21:41,460 --> 00:21:47,840
+human red cells، وهنا بسميه Rosular، نفس الفكرة ونفس
+
+286
+00:21:47,840 --> 00:21:51,480
+الشيء، بس يعني إيش الـ particles المحمل عليها الـ
+
+287
+00:21:51,480 --> 00:21:56,920
+Antibody، هنا عندي RBCs، هنا بقولك الـ Sensitized
+
+288
+00:21:56,920 --> 00:22:00,580
+RBCs، بتكون، هذا الفحص يعتبر more sensitive than
+
+289
+00:22:00,580 --> 00:22:05,380
+Latex، يعني ممكن الـ Latex أحياناً يعطيني Negative،
+
+290
+00:22:05,380 --> 00:22:08,720
+لكن هذا يعطيني Positive، ليش؟ لأن هذا More
+
+291
+00:22:08,720 --> 00:22:12,220
+Sensitive، وبتفاعل مع التركيزات القليلة من الـ
+
+292
+00:22:12,220 --> 00:22:17,260
+Antibody، بقوة أفضل من الـ Latex Particles، الإثنين
+
+293
+00:22:17,260 --> 00:22:22,840
+متاحين، والإثنين ممكن نشتغل عليهم بنفس الطريقة، طيب،
+
+294
+00:22:22,840 --> 00:22:27,340
+الآن لو طلع معايا هذا الفحص Positive، على إيش بدل؟
+
+295
+00:22:27,340 --> 00:22:33,170
+يعني إحنا بنربط الآن النتيجة مع الـ Symptoms والـ
+
+296
+00:22:33,170 --> 00:22:38,170
+Clinical History، بقولك إذا كانت أعطاني هذا الفحص
+
+297
+00:22:38,170 --> 00:22:43,810
+Positive، وكان المريض هذا عنده Symptoms و Signs للـ
+
+298
+00:22:43,810 --> 00:22:48,570
+Rheumatoid Arthritis، ووجود RF Positive بمستوى يعني
+
+299
+00:22:48,570 --> 00:22:52,190
+مرتفع، أو بتيتر مرتفع، غالباً بيرجح إنه حالة
+
+300
+00:22:52,190 --> 00:22:58,900
+Rheumatoid Arthritis، وعادة تتناسب الأعراض والـ
+
+301
+00:22:58,900 --> 00:23:02,320
+Prognosis مع نسبة الـ RF، يعني كل ما كان الـ RF
+
+302
+00:23:02,320 --> 00:23:06,960
+أعلى، كل ما كانت الأعراض أشد حدة وكان المرض الـ
+
+303
+00:23:06,960 --> 00:23:12,460
+Prognosis له أسوأ، لكن بقولك في ناس يعني تقريباً 20
+
+304
+00:23:12,460 --> 00:23:15,060
+% من الناس بيكون عندهم الأعراض، بيكون عندهم
+
+305
+00:23:15,060 --> 00:23:18,680
+Rheumatoid Arthritis، لكن بيعطوني False Negative
+
+306
+00:23:18,680 --> 00:23:23,560
+Result، في هذه الحالات، في عندنا فحص ثاني اللي هو Anti-
+
+307
+00:23:23,560 --> 00:23:27,400
+CCP Antibody، عبارة عن Antibody بيعطيني Positive،
+
+308
+00:23:27,400 --> 00:23:30,300
+وبيعمل Confirmation للـ Rheumatoid Arthritis،
+
+309
+00:23:30,300 --> 00:23:38,500
+خلينا نشوف بعد ذلك إيش هو Anti-CCP، طيب
+
+310
+00:23:38,500 --> 00:23:44,940
+هلقيت بقولك الـ Positive RF Result ممكن يكون في
+
+311
+00:23:44,940 --> 00:23:49,620
+قريب من 5% من الـ individuals، وفي مرضى في عندهم
+
+312
+00:23:49,620 --> 00:23:53,180
+أعراض ثانية ممكن يعطيكي RF Positive،  Sjögren’s
+
+313
+00:23:53,180 --> 00:23:57,480
+Syndrome، هذا عبارة عن مرض Autoimmune Disease بيأثر
+
+314
+00:23:57,480 --> 00:24:01,520
+على... بيعمل جفاف في الـ mucous membrane، ويله
+
+315
+00:24:01,520 --> 00:24:04,340
+أعراض معينة في الـ lungs، في حالات الـ
+
+316
+00:24:04,340 --> 00:24:07,860
+endocarditis، في حالات الـ tuberculosis، syphilis،
+
+317
+00:24:07,860 --> 00:24:12,480
+HIV، hepatitis، infectious mononucleosis، بعض أنواع
+
+318
+00:24:12,480 --> 00:24:15,580
+الـ cancers زي الليوكيميا والـ multiple myeloma، في
+
+319
+00:24:15,580 --> 00:24:18,340
+بعض الـ parasitic infections، في بعض الـ diseases زي
+
+320
+00:24:18,340 --> 00:24:26,620
+الـ liver، kidney، lung diseases، هذه كلها حالات ممكن
+
+321
+00:24:26,620 --> 00:24:31,660
+ألاقي إن الـ RF فيها ارتفع وعطاني Positive Result،
+
+322
+00:24:31,660 --> 00:24:35,420
+لكن non-specific، يعني ماهيش Rheumatoid Arthritis،
+
+323
+00:24:35,420 --> 00:24:40,260
+طبعاً هنا بقولك ملاحظة، الـ RF is not used to
+
+324
+00:24:40,260 --> 00:24:43,580
+diagnose or monitor these other conditions، يعني
+
+325
+00:24:43,580 --> 00:24:47,100
+أنا لو طلعت معايا الـ RF Positive في واحد من هدول،
+
+326
+00:24:47,450 --> 00:24:51,190
+بروحيش أستخدمه عشان أعمل مثلاً Hepatitis، بروحيش
+
+327
+00:24:51,190 --> 00:24:54,410
+أستخدم الـ RF عشان أعمل follow-up للـ Hepatitis، لأ،
+
+328
+00:24:54,410 --> 00:24:58,370
+يعني ممكن يرتفع وينزل بشكل عشوائي، مش منتظم في هذا
+
+329
+00:24:58,370 --> 00:25:00,830
+الـ disease، يعني ما أستخدمه لا للمتابعة ولا للـ
+
+330
+00:25:00,830 --> 00:25:04,290
+diagnosis، بس هو بقولك ممكن تكون كـ interfering
+
+331
+00:25:04,290 --> 00:25:13,270
+factors مع النتيجة تاعته هنا،
+
+332
+00:25:13,270 --> 00:25:18,580
+في عندنا ملاحظة، If the result is positive then do
+
+333
+00:25:18,580 --> 00:25:21,200
+serial dilution to determine the accurate
+
+334
+00:25:21,200 --> 00:25:25,180
+titration of RF in serum، هذه قلناها، إن أنا لازم
+
+335
+00:25:25,180 --> 00:25:28,480
+أعمل titration عشان أحدد الـ titration تاع الـ RF،
+
+336
+00:25:28,480 --> 00:25:32,380
+Semi-quantitative method، قلت لكم كيف بعمل dilution
+
+337
+00:25:32,380 --> 00:25:37,640
+بالقنابيب، وبأخذ من القنابيب هذه وبشتغل الـ RF عشان
+
+338
+00:25:37,640 --> 00:25:43,260
+أشوف الـ titration الصحيح للعينة، طيب الـ Negative
+
+339
+00:25:43,260 --> 00:25:46,610
+result from the direct agglutination doesn't rule
+
+340
+00:25:46,610 --> 00:25:50,110
+out rheumatoid arthritis، and positive result is
+
+341
+00:25:50,110 --> 00:25:53,550
+not specific for rheumatoid arthritis، هنا بقولك
+
+342
+00:25:53,550 --> 00:25:58,230
+الـ Negative لا تستثني، والـ Positive مش مؤكدة، هنا
+
+343
+00:25:58,230 --> 00:26:01,650
+بقولك مثال على الـ Negative، Prozone phenomena،
+
+344
+00:26:01,650 --> 00:26:06,090
+أحياناً يا بنات، فاكرين لما رسمت لكم الجدول، قلت لكم
+
+345
+00:26:06,090 --> 00:26:10,050
+لازم تبقى كمية الـ Antigen متناسبة مع كمية الـ Antibody،
+
+346
+00:26:10,050 --> 00:26:13,390
+عشان يعطيكي Positive، إذا كانت كمية الـ Antibody
+
+347
+00:26:13,390 --> 00:26:16,190
+عالية، هيعطيكي False Negative، وإذا كانت كمية الـ
+
+348
+00:26:16,190 --> 00:26:20,230
+Antigen عالية، هيعطيكي False Negative، فبالتالي
+
+349
+00:26:20,230 --> 00:26:25,930
+أحياناً تبقى تركيز الـ Antibodies عالي جداً، ولما
+
+350
+00:26:25,930 --> 00:26:29,210
+أجي أشتغل مباشرة منه ما بيعطيكيش Positive، حتى وهو
+
+351
+00:26:29,210 --> 00:26:33,770
+موجود، ليش؟ لأنه في عندنا ظاهرة بيسموها Prozone
+
+352
+00:26:33,770 --> 00:26:37,090
+phenomena، لما يبقى الـ titer  على الـ Antibody عالي،
+
+353
+00:26:37,090 --> 00:26:41,860
+هيعطيكي False Negative، لقيت لما إنت تيجي تعملي الـ
+
+354
+00:26:41,860 --> 00:26:45,980
+Dilution، أول titer وثاني titer ممكن يعطيك Negative،
+
+355
+00:26:45,980 --> 00:26:50,160
+لكن بعد هيك يبلش يعطيك Positive، إذا ظهرت عندك هذه
+
+356
+00:26:50,160 --> 00:26:54,860
+الشغلة، بدل على إنه الـ titer عالي كتير، وظهرت عندي
+
+357
+00:26:54,860 --> 00:27:00,800
+Prozone phenomena، هي اللي منعت الـ Antibody إنه
+
+358
+00:27:00,800 --> 00:27:08,320
+يتفاعل بشكل صحيح، طيب إيش معنى الكلام؟ معنى الكلام
+
+359
+00:27:08,320 --> 00:27:14,610
+أنه سواء طلعت معاك العينة Positive أو Negative،
+
+360
+00:27:14,610 --> 00:27:19,150
+المفروض تعمليها Dilution، وتشوفي الـ titer تاعها، لأن
+
+361
+00:27:19,150 --> 00:27:21,990
+Positive عرفنا ليش، عشان نشوف الـ titer، طب Negative،
+
+362
+00:27:21,990 --> 00:27:24,910
+طب هو ممكن يبقى False Negative، الـ titer عالي عشان
+
+363
+00:27:24,910 --> 00:27:28,450
+هيك ما عطانيش Positive، فلما باجي بعمل Dilution
+
+364
+00:27:28,450 --> 00:27:32,910
+للـ Negative Sample، وتعطي Positive بعد هيك، متأكد
+
+365
+00:27:32,910 --> 00:27:35,570
+من وجود Prozone phenomena،
+
+366
+00:27:41,410 --> 00:27:45,450
+إيش في عندي بعض الـ interfering factors، زي بقولك لو
+
+367
+00:27:45,450 --> 00:27:48,370
+كانت الـ lipids أو الـ cryoglobulins عالية، ممكن
+
+368
+00:27:48,370 --> 00:27:52,890
+تعطينا False Positive، الـ IgG عالية ممكن تعطي False
+
+369
+00:27:52,890 --> 00:27:57,030
+Positive، لو كان في عندنا activated complement برضه
+
+370
+00:27:57,030 --> 00:28:03,330
+ممكن تعطي False Positive results، نيجي
+
+371
+00:28:03,330 --> 00:28:08,030
+لاللي هو الفحص الأهم في تشخيص الـ Rheumatoid
+
+372
+00:28:08,030 --> 00:28:12,120
+Arthritis، اللي هو Cyclic Citrullinated Peptide
+
+373
+00:28:12,120 --> 00:28:16,580
+Antibody، هذا عادة بنطلبه، صار يعني لما بيطلع عندنا
+
+374
+00:28:16,580 --> 00:28:19,060
+الـ Rheumatoid Factor Positive، بيروح وبيطلبه الـ
+
+375
+00:28:19,060 --> 00:28:22,860
+Cyclic Citrullinated Peptide، هو فحص لسه مش يعني
+
+376
+00:28:22,860 --> 00:28:27,900
+كتير، يعني مش كتير معروف، أو ما بينطلبش على شكل واسع،
+
+377
+00:28:27,900 --> 00:28:31,880
+أو على نطاق واسع، بس الصحيح هو كتير أفضل من الـ RF،
+
+378
+00:28:31,880 --> 00:28:36,000
+بنطلبه معاه عشان يحدد الـ severity للـ disease والـ
+
+379
+00:28:36,000 --> 00:28:39,780
+prognosis، في أشياء ثانية حكينا إنها بتنطلب زي
+
+380
+00:28:39,780 --> 00:28:43,200
+الـ ESR والـ C-Reactive Protein، خلينا نشوف الـ
+
+381
+00:28:43,200 --> 00:28:47,180
+Cyclic Citrullinated Peptide، هذا عبارة عن إيه؟ هذا
+
+382
+00:28:47,180 --> 00:28:55,640
+عبارة عن Autoantibody، تمام؟ لا، إيش؟ Directed
+
+383
+00:28:55,640 --> 00:28:59,200
+against Cyclic Citrullinated Peptide، خلينا نشوف
+
+384
+00:28:59,200 --> 00:29:05,800
+إيش هي الـ Cyclic Citrullinated Peptide، الـ
+
+385
+00:29:05,800 --> 00:29:08,970
+Cyclic Citrullinated Antibody، أو
+
+386
+00:29:08,970 --> 00:29:11,670
+Anticyclic Citrullinated Peptide Antibody، كيف
+
+387
+00:29:11,670 --> 00:29:15,570
+بتكون في الجسم و ليش بتكون؟ هلقيت إحنا عارفين الـ
+
+388
+00:29:15,570 --> 00:29:18,510
+metabolism للـ Amino Acids، في عندي الـ Arginine،
+
+389
+00:29:18,510 --> 00:29:22,250
+نتيجة الـ metabolism بتاعه بتكون عندنا الـ
+
+390
+00:29:22,250 --> 00:29:25,450
+Citrulline، الـ Citrulline برضه عبارة عن Amino Acid
+
+391
+00:29:25,450 --> 00:29:28,910
+ثاني، هلقيت بقولك في مرض الـ Rheumatoid Arthritis،
+
+392
+00:29:29,630 --> 00:29:34,630
+وجدوا إن الـ Citrulline بتتحول أو بتكون على وثيرة
+
+393
+00:29:34,630 --> 00:29:39,890
+عالية، يعني بتكون بكمية كبيرة، الآن بتكون الـ
+
+3
\ No newline at end of file
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/8BQh-SbCWXM_raw.json b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/8BQh-SbCWXM_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..e6f8c0f90e139032dc1f74d513f9bef9a044cf0f
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/8BQh-SbCWXM_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 3133, "start": 1.85, "end": 31.33, "text": "بسم الله الرحمن الرحيم اليوم ان شاء الله رب العالمين راح ناخد أول تطبيق على موضوع ال agglutination طبعا هو الشغل العملي لإله هيكون agglutination هناخد تطبيقات كتير على ال agglutination أول واحد هيكون rheumatoid factor اختصاره RF أول قبل ما نحكي عن ال rheumatoid factor بدنا نشوف مع بعض", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 45595, 20498, 16472, 13412, 16606, 21984, 12602, 3555, 18863, 45340, 9957, 12602, 39319, 8717, 47283, 3215, 5551, 12610, 6055, 9566, 21292, 4587, 15844, 3714, 2407, 11242, 45367, 2423, 623, 7191, 325, 2486, 23032, 3555, 3615, 995, 31439, 25124, 17082, 1211, 18863, 2304, 20292, 5296, 28814, 43761, 39896, 30544, 623, 7191, 325, 2486, 8032, 1863, 47283, 3215, 6055, 9566, 21292, 4587, 9307, 9122, 2655, 13546, 15844, 2423, 623, 7191, 325, 2486, 5551, 12610, 36764, 24401, 39896, 30544, 50100, 449, 2513, 327, 5952, 1975, 46456, 9381, 9640, 3224, 26204, 5551, 12610, 12174, 36150, 19446, 8717, 5016, 4117, 1829, 18871, 2423, 50100, 449, 2513, 327, 5952, 47525, 8315, 8717, 8592, 38688, 20449, 45030, 11242], "avg_logprob": -0.09278151122006503, "compression_ratio": 1.8666666666666667, "no_speech_prob": 0.0002663135528564453, "words": [{"start": 1.85, "end": 2.21, "word": "بسم", "probability": 0.88671875}, {"start": 2.21, "end": 2.49, "word": " الله", "probability": 0.9375}, {"start": 2.49, "end": 3.05, "word": " الرحمن", "probability": 0.970703125}, {"start": 3.05, "end": 3.55, "word": " الرحيم", "probability": 0.9951171875}, {"start": 3.55, "end": 5.27, "word": " اليوم", "probability": 0.905517578125}, {"start": 5.27, "end": 5.41, "word": " ان", "probability": 0.36279296875}, {"start": 5.41, "end": 5.55, "word": " شاء", "probability": 0.97802734375}, {"start": 5.55, "end": 5.77, "word": " الله", "probability": 0.95849609375}, {"start": 5.77, "end": 6.23, "word": " رب", "probability": 0.939697265625}, {"start": 6.23, "end": 6.89, "word": " العالمين", 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"word": " rheumatoid", "probability": 0.79595947265625}, {"start": 21.15, "end": 21.79, "word": " factor", "probability": 0.90185546875}, {"start": 21.79, "end": 23.01, "word": " اختصاره", "probability": 0.9486328125}, {"start": 23.01, "end": 24.13, "word": " RF", "probability": 0.8662109375}, {"start": 24.13, "end": 27.63, "word": " أول", "probability": 0.81201171875}, {"start": 27.63, "end": 28.03, "word": " قبل", "probability": 0.85205078125}, {"start": 28.03, "end": 28.15, "word": " ما", "probability": 0.9306640625}, {"start": 28.15, "end": 28.55, "word": " نحكي", "probability": 0.9921875}, {"start": 28.55, "end": 28.73, "word": " عن", "probability": 0.9892578125}, {"start": 28.73, "end": 28.81, "word": " ال", "probability": 0.83740234375}, {"start": 28.81, "end": 29.35, "word": " rheumatoid", "probability": 0.98291015625}, {"start": 29.35, "end": 29.83, "word": " factor", "probability": 0.9287109375}, {"start": 29.83, "end": 30.35, "word": " بدنا", "probability": 0.895751953125}, 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"word": " الأعراض", "probability": 0.9638671875}, {"start": 310.88, "end": 311.78, "word": " المصاحبة", "probability": 0.977783203125}, {"start": 311.78, "end": 312.86, "word": " للـRheumatoid", "probability": 0.9066685267857143}, {"start": 312.86, "end": 313.84, "word": " Arthritis؟", "probability": 0.90771484375}], "temperature": 1.0}, {"id": 12, "seek": 34135, "start": 314.43, "end": 341.35, "text": "أول حاجة pain بيبدأ يشكي المريض من ألم بالمفاصل سخونة بالمفصل warmth swelling انتفاخ morning stiffness in the joint صبح المفصل مش قادر يحركه nodule under the skin بتلاقي زي حبيبات تحت الجلد if the disease has progressed لو المرض تطور", "tokens": [10721, 12610, 11331, 26108, 3660, 1822, 4724, 1829, 44510, 10721, 7251, 8592, 4117, 1829, 9673, 16572, 11242, 9154, 5551, 19528, 20666, 2304, 5172, 33546, 1211, 8608, 9778, 11536, 3660, 20666, 2304, 5172, 36520, 24737, 33127, 16472, 2655, 5172, 47283, 2446, 37759, 294, 264, 7225, 20328, 49628, 9673, 5172, 36520, 37893, 12174, 18513, 2288, 7251, 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Passive فهمنا لياش واضحة تمام نيجي لطريقة الشغل العينة اللي أنا باخدها Serum لا يجوز بأي حال من الأحوال أني أخد بلازمة لأن البلازمة فيها Fibrinogen والـFibrinogen for sure هيعطيني مع الـRheumatoid Factor Positive", "tokens": [3615, 8592, 7649, 39896, 4117, 37495, 22653, 37893, 8032, 2655, 1863, 3794, 1829, 4587, 13672, 1829, 31439, 10319, 488, 34051, 26314, 405, 10319, 488, 3714, 43020, 1975, 34268, 26890, 3224, 10319, 488, 4032, 2304, 43020, 8978, 5551, 15042, 19452, 6055, 7649, 10632, 1975, 2655, 15040, 38436, 3224, 37495, 22653, 3714, 4117, 2655, 37746, 18871, 3224, 16472, 3224, 26314, 405, 10319, 488, 6156, 16095, 8315, 32239, 33599, 4032, 46958, 5016, 3660, 46811, 10943, 8717, 1829, 7435, 1829, 5296, 9566, 16572, 28671, 25124, 17082, 1211, 18863, 9957, 3660, 13672, 1829, 41850, 4724, 47283, 3215, 11296, 4210, 449, 20193, 7251, 7435, 2407, 11622, 4724, 10721, 1829, 11331, 6027, 9154, 16247, 5016, 2407, 6027, 14739, 1829, 5551, 9778, 3215, 4724, 1211, 31377, 46007, 5296, 33456, 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أني", "probability": 0.69921875}, {"start": 1018.93, "end": 1019.25, "word": " أخد", "probability": 0.8072916666666666}, {"start": 1019.25, "end": 1019.79, "word": " بلازمة", "probability": 0.8359375}, {"start": 1019.79, "end": 1020.75, "word": " لأن", "probability": 0.934326171875}, {"start": 1020.75, "end": 1021.27, "word": " البلازمة", "probability": 0.7646484375}, {"start": 1021.27, "end": 1021.57, "word": " فيها", "probability": 0.987060546875}, {"start": 1021.57, "end": 1022.35, "word": " Fibrinogen", "probability": 0.74462890625}, {"start": 1022.35, "end": 1023.59, "word": " والـFibrinogen", "probability": 0.7666015625}, {"start": 1023.59, "end": 1024.61, "word": " for", "probability": 0.7529296875}, {"start": 1024.61, "end": 1025.01, "word": " sure", "probability": 0.95751953125}, {"start": 1025.01, "end": 1025.75, "word": " هيعطيني", "probability": 0.92041015625}, {"start": 1025.75, "end": 1025.93, "word": " مع", "probability": 0.9658203125}, {"start": 1025.93, "end": 1026.47, "word": " الـRheumatoid", "probability": 0.79150390625}, {"start": 1026.47, "end": 1026.95, "word": " Factor", "probability": 0.692626953125}, {"start": 1026.95, "end": 1027.31, "word": " Positive", "probability": 0.7041015625}], "temperature": 1.0}, {"id": 40, "seek": 105033, "start": 1028.39, "end": 1050.33, "text": "عشان هيك منفعش أخد بلازما خالص باخد serum أو sinovie ال fluid sample الآن كيف طريقة الفحص هذا بعمله في عندي slide slide هذه يعني بختارها إما سودة أو بيضة حسب لون ال reagent إذا كان ال reagent أبيض بختار خلفية سودة", "tokens": [3615, 8592, 7649, 39896, 4117, 3714, 1863, 5172, 3615, 8592, 5551, 9778, 3215, 4724, 1211, 31377, 15042, 16490, 6027, 9381, 4724, 47283, 3215, 32755, 34051, 3343, 5179, 414, 2423, 9113, 6889, 6024, 48506, 9122, 33911, 23032, 16572, 28671, 27188, 5016, 9381, 23758, 4724, 25957, 43761, 8978, 18871, 16254, 4137, 4137, 29538, 37495, 22653, 4724, 46456, 9640, 11296, 11933, 15042, 8608, 23328, 3660, 34051, 4724, 1829, 11242, 3660, 11331, 35457, 5296, 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"word": " ال", "probability": 0.986328125}, {"start": 1046.91, "end": 1047.39, "word": " reagent", "probability": 0.70068359375}, {"start": 1047.39, "end": 1047.67, "word": " إذا", "probability": 0.967529296875}, {"start": 1047.67, "end": 1047.93, "word": " كان", "probability": 0.99658203125}, {"start": 1047.93, "end": 1048.03, "word": " ال", "probability": 0.9853515625}, {"start": 1048.03, "end": 1048.47, "word": " reagent", "probability": 0.979736328125}, {"start": 1048.47, "end": 1048.93, "word": " أبيض", "probability": 0.9697265625}, {"start": 1048.93, "end": 1049.41, "word": " بختار", "probability": 0.9459635416666666}, {"start": 1049.41, "end": 1049.91, "word": " خلفية", "probability": 0.7887369791666666}, {"start": 1049.91, "end": 1050.33, "word": " سودة", "probability": 0.9830729166666666}], "temperature": 1.0}, {"id": 41, "seek": 107651, "start": 1050.75, "end": 1076.51, "text": "إذا كان الـ Reagent أزرق أو أي لون تاني بختار خلفية بيضة عشان هي خلفية تساعد على يعني بختار خلفية 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النتيجة", "probability": 0.941650390625}], "temperature": 1.0}, {"id": 52, "seek": 137773, "start": 1351.33, "end": 1377.73, "text": "مع الـ Symptoms و الـ Clinical History بقولك إذا كانت أعطاني هذا الفحص Positive وكان المريض هذا عنده Symptoms و Size للـ Rheumatoid Arthritis وجود RF Positive بمستوى يعني مرتفع أو بتايتر مرتفع غالباً بيرجح إنه حالة Rheumatoid Arthritis وعادة تتناسب الأعراض", "tokens": [2304, 3615, 2423, 39184, 28877, 662, 4785, 4032, 2423, 39184, 47942, 12486, 4724, 39648, 4117, 11933, 15730, 25961, 2655, 5551, 3615, 9566, 7649, 1829, 23758, 27188, 5016, 9381, 46326, 4032, 41361, 9673, 16572, 11242, 23758, 43242, 3224, 28877, 662, 4785, 4032, 35818, 24976, 39184, 497, 675, 449, 2513, 327, 1587, 392, 24580, 49610, 23328, 26204, 46326, 4724, 2304, 14851, 2407, 7578, 37495, 22653, 3714, 43500, 5172, 3615, 34051, 39894, 995, 36081, 2288, 3714, 43500, 5172, 3615, 32771, 6027, 3555, 995, 14111, 4724, 13546, 7435, 5016, 36145, 3224, 11331, 6027, 3660, 497, 675, 449, 2513, 327, 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"probability": 0.736572265625}], "temperature": 1.0}, {"id": 70, "seek": 188097, "start": 1855.71, "end": 1880.97, "text": "وهيكون Severe و الـ Prognosis لإله يعني هيكون مش بسيط، هيكون سيئة طيب لو كان المريض Positive للـ CCP و Negative للـ RF أو ال عنده Low Level من اتنين هذا بيدل على إنه مريض Rheumatoid Arthritis لكن Early Stage لسه الـ Title للـ Antibodies ما ارتفعش", "tokens": [2407, 3224, 1829, 30544, 1100, 5887, 4032, 2423, 39184, 1705, 4568, 8211, 5296, 28814, 43761, 37495, 22653, 39896, 30544, 37893, 4724, 3794, 1829, 9566, 12399, 39896, 30544, 8608, 1829, 19986, 3660, 23032, 1829, 3555, 45164, 25961, 9673, 16572, 11242, 46326, 24976, 39184, 27876, 4032, 43230, 24976, 39184, 26204, 34051, 2423, 43242, 3224, 17078, 16872, 9154, 1975, 2655, 1863, 9957, 23758, 4724, 25708, 1211, 15844, 36145, 3224, 3714, 16572, 11242, 497, 675, 449, 2513, 327, 1587, 392, 24580, 44381, 18344, 25907, 5296, 3794, 3224, 2423, 39184, 26768, 24976, 39184, 5130, 897, 6087, 19446, 1975, 43500, 5172, 3615, 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"word": " مريض", "probability": 0.822998046875}, {"start": 1874.91, "end": 1875.49, "word": " Rheumatoid", "probability": 0.852392578125}, {"start": 1875.49, "end": 1876.31, "word": " Arthritis", "probability": 0.93994140625}, {"start": 1876.31, "end": 1877.35, "word": " لكن", "probability": 0.9609375}, {"start": 1877.35, "end": 1877.95, "word": " Early", "probability": 0.87890625}, {"start": 1877.95, "end": 1878.49, "word": " Stage", "probability": 0.798828125}, {"start": 1878.49, "end": 1878.95, "word": " لسه", "probability": 0.8665364583333334}, {"start": 1878.95, "end": 1879.15, "word": " الـ", "probability": 0.684326171875}, {"start": 1879.15, "end": 1879.41, "word": " Title", "probability": 0.52001953125}, {"start": 1879.41, "end": 1879.69, "word": " للـ", "probability": 0.937744140625}, {"start": 1879.69, "end": 1880.21, "word": " Antibodies", "probability": 0.9498697916666666}, {"start": 1880.21, "end": 1880.37, "word": " ما", "probability": 0.5966796875}, {"start": 1880.37, "end": 1880.97, "word": " ارتفعش", "probability": 0.93525390625}], "temperature": 1.0}, {"id": 71, "seek": 190463, "start": 1881.81, "end": 1904.63, "text": "لو بعد فترة إيجيني عندنا هنلاقيه مرتفع وهنلاقي إن الشخص هذا عنده قابلية إنه يكون روماتويد أرثريتس طيب لو كان Negative للـ CCP و Positive للـ RF نتوقع إنه يكون مش روماتويد أرثريتس ممكن يكون أي interfering factor أو inflammation أعطاني Positive RF طيب", "tokens": [1211, 2407, 39182, 6156, 2655, 25720, 11933, 1829, 7435, 9957, 1829, 43242, 8315, 8032, 1863, 15040, 38436, 3224, 3714, 43500, 5172, 3615, 4032, 3224, 1863, 15040, 38436, 36145, 25124, 9778, 9381, 23758, 43242, 3224, 12174, 16758, 1211, 10632, 36145, 3224, 7251, 30544, 12602, 20498, 9307, 2407, 25708, 5551, 2288, 49115, 36081, 3794, 23032, 1829, 3555, 45164, 25961, 43230, 24976, 39184, 27876, 4032, 46326, 24976, 39184, 26204, 8717, 2655, 30543, 3615, 36145, 3224, 7251, 30544, 37893, 12602, 20498, 9307, 2407, 25708, 5551, 2288, 49115, 36081, 3794, 3714, 43020, 7251, 30544, 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كان الشخص Negative Leptinane معنى الكلام إنه ما عنده روماتويد أرثرايتس ولا هيكون روماتويد أرثرايتس تمام هك؟ يعني خلاصة الكلام إنه أفضل إشي في ال diagnosis الـCCB، Anti-CCB زي ما قلنا الـAnti-CCB هو فحص إلى حد ما حديث ومش كتير منتشر لكن الصحيح هو المفروض الآن ينطلب باستمرار", "tokens": [1211, 2407, 25961, 25124, 9778, 9381, 43230, 441, 5250, 259, 1929, 20449, 1863, 7578, 2423, 28820, 10943, 36145, 3224, 19446, 43242, 3224, 12602, 20498, 9307, 2407, 25708, 5551, 2288, 49115, 995, 36081, 3794, 49429, 39896, 30544, 12602, 20498, 9307, 2407, 25708, 5551, 2288, 49115, 995, 36081, 3794, 46811, 10943, 8032, 4117, 22807, 37495, 22653, 16490, 1211, 33546, 3660, 2423, 28820, 10943, 36145, 3224, 5551, 5172, 11242, 1211, 11933, 8592, 1829, 8978, 2423, 15217, 2423, 39184, 11717, 33, 12399, 27757, 12, 11717, 33, 30767, 1829, 19446, 12174, 1211, 8315, 2423, 39184, 35807, 72, 12, 11717, 33, 31439, 6156, 5016, 9381, 30731, 11331, 3215, 19446, 11331, 16254, 12984, 4032, 2304, 8592, 9122, 2655, 13546, 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"end": 1924.2, "word": " قلنا", "probability": 0.9381510416666666}, {"start": 1924.2, "end": 1924.64, "word": " الـAnti", "probability": 0.8853759765625}, {"start": 1924.64, "end": 1925.06, "word": "-CCB", "probability": 0.978515625}, {"start": 1925.06, "end": 1925.3, "word": " هو", "probability": 0.97021484375}, {"start": 1925.3, "end": 1925.78, "word": " فحص", "probability": 0.9562174479166666}, {"start": 1925.78, "end": 1926.08, "word": " إلى", "probability": 0.8525390625}, {"start": 1926.08, "end": 1926.34, "word": " حد", "probability": 0.99560546875}, {"start": 1926.34, "end": 1926.56, "word": " ما", "probability": 0.96533203125}, {"start": 1926.56, "end": 1927.12, "word": " حديث", "probability": 0.9794921875}, {"start": 1927.12, "end": 1927.36, "word": " ومش", "probability": 0.8434244791666666}, {"start": 1927.36, "end": 1927.68, "word": " كتير", "probability": 0.9557291666666666}, {"start": 1927.68, "end": 1928.28, "word": " منتشر", "probability": 0.98095703125}, {"start": 1928.28, "end": 1929.02, "word": " لكن", "probability": 0.9521484375}, {"start": 1929.02, "end": 1929.64, "word": " الصحيح", "probability": 0.9952392578125}, {"start": 1929.64, "end": 1929.82, "word": " هو", "probability": 0.99658203125}, {"start": 1929.82, "end": 1930.38, "word": " المفروض", "probability": 0.9520263671875}, {"start": 1930.38, "end": 1930.8, "word": " الآن", "probability": 0.793701171875}, {"start": 1930.8, "end": 1931.36, "word": " ينطلب", "probability": 0.9146728515625}, {"start": 1931.36, "end": 1932.72, "word": " باستمرار", "probability": 0.98046875}], "temperature": 1.0}, {"id": 73, "seek": 196267, "start": 1933.15, "end": 1962.67, "text": "مع الـ Rheumatoid factor لأنه more specific من الـ Rheumatoid factor وبيعطيني نتائج أفضل الـ CCP Antibody مابيعطيش مع الـ Autoimmune disease الأخرى false positive زي الـ RF مابيعمل الـ RF شفنا قائمة طويلة من الأمراض بيعطي معاها positive بينما هذا لأ مابيعطي positive غير في حالات Rheumatoid arthritis هيك بنكون خلصنا موضوع الـ RF", "tokens": [2304, 3615, 2423, 39184, 497, 675, 449, 2513, 327, 5952, 5296, 33456, 3224, 544, 2685, 9154, 2423, 39184, 497, 675, 449, 2513, 327, 5952, 4032, 21292, 3615, 9566, 9957, 1829, 8717, 2655, 16373, 7435, 5551, 5172, 11242, 1211, 2423, 39184, 27876, 5130, 897, 843, 19446, 21292, 3615, 9566, 1829, 8592, 20449, 2423, 39184, 13738, 49031, 4752, 16247, 34740, 7578, 7908, 3353, 30767, 1829, 2423, 39184, 26204, 19446, 21292, 25957, 1211, 2423, 39184, 26204, 13412, 5172, 8315, 12174, 16373, 46007, 23032, 2407, 26895, 3660, 9154, 16247, 29973, 46958, 4724, 40228, 9566, 1829, 20449, 995, 11296, 3353, 49374, 15042, 23758, 5296, 10721, 19446, 21292, 3615, 9566, 1829, 3353, 32771, 13546, 8978, 11331, 6027, 9307, 497, 675, 449, 2513, 327, 35956, 39896, 4117, 44945, 30544, 16490, 1211, 9381, 8315, 3714, 2407, 11242, 45367, 2423, 39184, 26204], "avg_logprob": -0.12196828419370438, "compression_ratio": 1.7318840579710144, "no_speech_prob": 1.9490718841552734e-05, "words": [{"start": 1933.15, "end": 1933.81, "word": "مع", "probability": 0.946044921875}, {"start": 1933.81, "end": 1934.23, "word": " الـ", "probability": 0.977294921875}, {"start": 1934.23, "end": 1934.75, "word": " Rheumatoid", "probability": 0.9251953125}, {"start": 1934.75, "end": 1935.19, "word": " factor", "probability": 0.4111328125}, {"start": 1935.19, "end": 1935.65, "word": " لأنه", "probability": 0.93896484375}, {"start": 1935.65, "end": 1935.85, "word": " more", "probability": 0.18701171875}, {"start": 1935.85, "end": 1936.39, "word": " specific", "probability": 0.9716796875}, {"start": 1936.39, "end": 1937.19, "word": " من", "probability": 0.9638671875}, {"start": 1937.19, "end": 1937.61, "word": " الـ", "probability": 0.945068359375}, {"start": 1937.61, "end": 1938.07, "word": " Rheumatoid", "probability": 0.9650390625}, {"start": 1938.07, "end": 1938.57, "word": " factor", "probability": 0.93212890625}, {"start": 1938.57, "end": 1939.63, "word": " وبيعطيني", "probability": 0.778076171875}, {"start": 1939.63, "end": 1940.13, "word": " نتائج", "probability": 0.9942626953125}, {"start": 1940.13, "end": 1940.63, "word": " أفضل", "probability": 0.989990234375}, {"start": 1940.63, "end": 1941.37, "word": " الـ", "probability": 0.79052734375}, {"start": 1941.37, "end": 1941.65, "word": " CCP", "probability": 0.424560546875}, {"start": 1941.65, "end": 1942.35, "word": " Antibody", "probability": 0.8763020833333334}, {"start": 1942.35, "end": 1943.41, "word": " مابيعطيش", "probability": 0.8491617838541666}, {"start": 1943.41, "end": 1943.61, "word": " مع", "probability": 0.96875}, {"start": 1943.61, "end": 1943.81, "word": " الـ", "probability": 0.913330078125}, {"start": 1943.81, "end": 1944.31, "word": " Autoimmune", "probability": 0.781494140625}, {"start": 1944.31, "end": 1944.75, "word": " disease", "probability": 0.50390625}, {"start": 1944.75, "end": 1945.29, "word": " الأخرى", "probability": 0.9593098958333334}, {"start": 1945.29, "end": 1945.59, "word": " false", "probability": 0.381103515625}, {"start": 1945.59, "end": 1946.11, "word": " positive", "probability": 0.89013671875}, {"start": 1946.11, "end": 1946.45, "word": " زي", "probability": 0.977294921875}, {"start": 1946.45, "end": 1946.69, "word": " الـ", "probability": 0.954345703125}, {"start": 1946.69, "end": 1947.05, "word": " RF", "probability": 0.87451171875}, {"start": 1947.05, "end": 1947.69, "word": " مابيعمل", "probability": 0.8072509765625}, {"start": 1947.69, "end": 1948.21, "word": " الـ", "probability": 0.9658203125}, {"start": 1948.21, "end": 1948.43, "word": " RF", "probability": 0.97705078125}, {"start": 1948.43, "end": 1948.81, "word": " شفنا", "probability": 0.9083658854166666}, {"start": 1948.81, "end": 1949.19, "word": " قائمة", "probability": 0.9928385416666666}, {"start": 1949.19, "end": 1949.67, "word": " طويلة", "probability": 0.9727783203125}, {"start": 1949.67, "end": 1949.81, "word": " من", "probability": 0.99560546875}, {"start": 1949.81, "end": 1950.39, "word": " الأمراض", "probability": 0.9913736979166666}, {"start": 1950.39, "end": 1950.77, "word": " بيعطي", "probability": 0.9000244140625}, {"start": 1950.77, "end": 1951.07, "word": " معاها", "probability": 0.9676106770833334}, {"start": 1951.07, "end": 1951.45, "word": " positive", "probability": 0.84033203125}, {"start": 1951.45, "end": 1951.91, "word": " بينما", "probability": 0.7276611328125}, {"start": 1951.91, "end": 1952.27, "word": " هذا", "probability": 0.96728515625}, {"start": 1952.27, "end": 1952.93, "word": " لأ", "probability": 0.9619140625}, {"start": 1952.93, "end": 1953.59, "word": " مابيعطي", "probability": 0.9763671875}, {"start": 1953.59, "end": 1953.99, "word": " positive", "probability": 0.90625}, {"start": 1953.99, "end": 1954.35, "word": " غير", "probability": 0.980712890625}, {"start": 1954.35, "end": 1954.51, "word": " في", "probability": 0.9677734375}, {"start": 1954.51, "end": 1954.97, "word": " حالات", "probability": 0.9495442708333334}, {"start": 1954.97, "end": 1955.59, "word": " Rheumatoid", "probability": 0.91201171875}, {"start": 1955.59, "end": 1956.19, "word": " arthritis", "probability": 0.57861328125}, {"start": 1956.19, "end": 1960.81, "word": " هيك", "probability": 0.862548828125}, {"start": 1960.81, "end": 1961.29, "word": " بنكون", "probability": 0.960693359375}, {"start": 1961.29, "end": 1961.85, "word": " خلصنا", "probability": 0.990966796875}, {"start": 1961.85, "end": 1962.23, "word": " موضوع", "probability": 0.9970703125}, {"start": 1962.23, "end": 1962.45, "word": " الـ", "probability": 0.9921875}, {"start": 1962.45, "end": 1962.67, "word": " RF", "probability": 0.97900390625}], "temperature": 1.0}, {"id": 74, "seek": 196903, "start": 1963.47, "end": 1969.03, "text": "نتمنى من الله أن يجمعنا ونقوم بأداء الجزئية العملي لهذه الموضوع", "tokens": [29399, 27842, 7578, 9154, 21984, 14739, 7251, 7435, 2304, 3615, 8315, 4032, 1863, 4587, 20498, 4724, 10721, 3215, 16606, 25724, 11622, 19986, 10632, 18863, 2304, 20292, 46740, 24192, 9673, 2407, 11242, 45367], "avg_logprob": -0.08001893939393939, "compression_ratio": 1.2747252747252746, "no_speech_prob": 0.0, "words": [{"start": 1963.47, "end": 1964.17, "word": "نتمنى", "probability": 0.9404296875}, {"start": 1964.17, "end": 1964.31, "word": " من", "probability": 0.98486328125}, {"start": 1964.31, "end": 1964.57, "word": " الله", "probability": 0.94775390625}, {"start": 1964.57, "end": 1964.69, "word": " أن", "probability": 0.66455078125}, {"start": 1964.69, "end": 1965.41, "word": " يجمعنا", "probability": 0.99140625}, {"start": 1965.41, "end": 1966.19, "word": " ونقوم", "probability": 0.9271240234375}, {"start": 1966.19, "end": 1966.79, "word": " بأداء", "probability": 0.9656982421875}, {"start": 1966.79, "end": 1967.29, "word": " الجزئية", "probability": 0.90478515625}, {"start": 1967.29, "end": 1967.75, "word": " العملي", "probability": 0.8101399739583334}, {"start": 1967.75, "end": 1968.37, "word": " لهذه", "probability": 0.8759765625}, {"start": 1968.37, "end": 1969.03, "word": " الموضوع", "probability": 0.9989013671875}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1971.606375, "duration_after_vad": 1928.7287499999966}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/8BQh-SbCWXM_raw.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/8BQh-SbCWXM_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..980bf068d94b1ad9a30307d6c67ff92e9ae4c3ab
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/8BQh-SbCWXM_raw.srt
@@ -0,0 +1,1748 @@
+1
+00:00:01,850 --> 00:00:06,230
+بسم الله الرحمن الرحيم اليوم ان شاء الله رب
+
+2
+00:00:06,230 --> 00:00:10,470
+العالمين راح ناخد أول تطبيق على موضوع ال
+
+3
+00:00:10,470 --> 00:00:14,830
+agglutination طبعا هو الشغل العملي لإله هيكون
+
+4
+00:00:14,830 --> 00:00:17,570
+agglutination هناخد تطبيقات كتير على ال
+
+5
+00:00:17,570 --> 00:00:21,790
+agglutination أول واحد هيكون rheumatoid factor
+
+6
+00:00:21,790 --> 00:00:27,630
+اختصاره RF أول
+
+7
+00:00:27,630 --> 00:00:30,970
+قبل ما نحكي عن ال rheumatoid factor بدنا نشوف مع
+
+8
+00:00:30,970 --> 00:00:35,320
+بعضإيش هو الـ Rheumatoid Arthritis اللي بتتم
+
+9
+00:00:35,320 --> 00:00:39,580
+تشخيصه من خلال الـ Rheumatoid Factor Rheumatoid
+
+10
+00:00:39,580 --> 00:00:44,640
+Arthritis عبارة عن Chronic Autoimmune Inflammatory
+
+11
+00:00:44,640 --> 00:00:50,320
+Disorder عبارة عن Autoimmune Disease بيأثر بشكل
+
+12
+00:00:50,320 --> 00:00:58,680
+أساسي على مفاصل الـ hands الـ feet و other area in
+
+13
+00:00:58,680 --> 00:01:02,080
+the bodyas the disease progress يعني كل ما تطور
+
+14
+00:01:02,080 --> 00:01:08,220
+المرض هتلاقي أنه مناطق تانية بدت تتأثر بالجسم الـ
+
+15
+00:01:08,220 --> 00:01:11,940
+disease affects the lining of joint بيأثر على
+
+16
+00:01:11,940 --> 00:01:17,480
+البطانة أو الـ epithelium المبطن للمفصل مما يؤدي
+
+17
+00:01:17,480 --> 00:01:22,260
+إلى حدوث swelling and pain and inflammatory
+
+18
+00:01:22,260 --> 00:01:24,520
+symptoms
+
+19
+00:01:26,260 --> 00:01:31,920
+طبعاً هذا مع الوقت بيؤدي to bone erosion إيش يعني
+
+20
+00:01:31,920 --> 00:01:36,040
+bone erosion؟ تآكل في العظام وذوبان Unjoined
+
+21
+00:01:36,040 --> 00:01:40,980
+deformity مع الوقت بيسبب بالإضافة لتآكل العظام أو
+
+22
+00:01:40,980 --> 00:01:44,980
+سبب يعني تآكل العظام يؤدي إلى تشوهات في المفصل
+
+23
+00:01:44,980 --> 00:01:49,960
+أكثر المناطق اللي ممكن تتأثر بـ Rheumatoid
+
+24
+00:01:49,960 --> 00:01:55,100
+Arthritis اللي هي الـ tendons heart valve vessels
+
+25
+00:01:55,740 --> 00:02:00,480
+heart blood vessels subcutaneous tissue الـ lungs
+
+26
+00:02:00,480 --> 00:02:03,920
+يعني كل هذه الأماكن ممكن يصير فيها inflammation
+
+27
+00:02:03,920 --> 00:02:13,120
+وتتأثر بالـ rheumatoid arthritis rheumatoid
+
+28
+00:02:13,120 --> 00:02:18,020
+arthritis هو عبارة عن autoimmune disorder إيش يعني
+
+29
+00:02:18,020 --> 00:02:22,010
+autoimmune disorder طبعا إحنا عارفينإنه جهاز
+
+30
+00:02:22,010 --> 00:02:25,130
+المناع عنده القدرة على إنه يميز الـ «self» عن الـ
+
+31
+00:02:25,130 --> 00:02:31,610
+«non-self» في لحظة معينة بيفقد جهاز المناع هذه
+
+32
+00:02:31,610 --> 00:02:36,750
+القدرة وبصير يتعامل مع الـ «self-antigen» على إنها
+
+33
+00:02:36,750 --> 00:02:40,410
+«foreign antigen» وبيبلش يكونلها antibodies
+
+34
+00:02:40,410 --> 00:02:44,610
+وبيهاجمها طبعاً هذا بيؤدي لـ «inflammation»
+
+35
+00:02:44,610 --> 00:02:46,670
+«inflammation» وين بيكون؟ احنا لو تخيل ما هي
+
+36
+00:02:46,670 --> 00:02:52,150
+المفصلالمفصل فيه عند صينوفيال المفصل هي نفسه مغطى
+
+37
+00:02:52,150 --> 00:02:56,030
+بـ Cartilage فيه بعد الـ Cartilage صينوفيال ممبران
+
+38
+00:02:56,030 --> 00:03:00,270
+وبين العضمتين تعون المفصل فيه عند الصينوفيال الـ
+
+39
+00:03:00,270 --> 00:03:03,090
+Fluid فالـ EDD هيبلش يصير Inflammation في
+
+40
+00:03:03,090 --> 00:03:06,190
+الصينوفيال الممبران المحيط بهذه الصينوفيال الـ
+
+41
+00:03:06,190 --> 00:03:09,290
+Cavity الالتهاب اللي في الصينوفيال الممبران هذا
+
+42
+00:03:09,290 --> 00:03:15,000
+طبعاً راح يعمل تراكم للثائل بكمية كبيرةوطبعاً
+
+43
+00:03:15,000 --> 00:03:19,740
+inflammation من قلم و hotness و redness و swelling
+
+44
+00:03:19,740 --> 00:03:23,760
+وعدم القدرة على التأكل المفصل بعد ذلك طبعاً زي ما
+
+45
+00:03:23,760 --> 00:03:27,540
+قلتلكم مع الوقت بيبدأ يصير تآكل في العظام وتشوّف
+
+46
+00:03:27,540 --> 00:03:32,800
+في المفصل الـ Rheumatoid Arthritis يعتبر systemic
+
+47
+00:03:32,800 --> 00:03:37,700
+disease يعني ما بيأثر بس على المفاصل هلقيت الـ
+
+48
+00:03:37,700 --> 00:03:42,090
+autoimmune diseases احنا بنقسمها لنوعينالنوع
+
+49
+00:03:42,090 --> 00:03:45,850
+بيسموه Systemic Autoimmune Disease يعني ممكن يأثر
+
+50
+00:03:45,850 --> 00:03:51,070
+على أماكن كثيرة من الجسم الـ Lag والنوع التاني
+
+51
+00:03:51,070 --> 00:03:57,970
+Localized أو Non-Systemic النوع التاني بيأثر على
+
+52
+00:03:57,970 --> 00:04:03,550
+organ معين على خلية نوع معين من الخلايا على نسيج
+
+53
+00:04:03,550 --> 00:04:08,150
+معين لكن Rheumatoid Arthritis بيأثر على كل الجسم
+
+54
+00:04:08,150 --> 00:04:10,870
+كل الجسم ممكن يتأثر ويصير فيه مضاعفة
+
+55
+00:04:15,650 --> 00:04:21,070
+طيب نيجي التغيرات اللي ممكن تصير خلال الـ
+
+56
+00:04:21,070 --> 00:04:25,670
+Rheumatoid Arthritis بداية Formation of Granulated
+
+57
+00:04:25,670 --> 00:04:31,090
+Tissue that extends as vascular layer from the
+
+58
+00:04:31,090 --> 00:04:35,030
+margin towards the central of the affected joint
+
+59
+00:04:35,030 --> 00:04:41,230
+إيش يعني؟ بيبدأ يصير Granulated Tissue نسيج عامل
+
+60
+00:04:41,230 --> 00:04:48,560
+Granulation وهذا النسيج يمتدمن أطراف المفصل أو
+
+61
+00:04:48,560 --> 00:04:53,000
+الأطراف المنطقة الملتهبة في المفصل وتمتد إلى الوسط
+
+62
+00:04:53,000 --> 00:04:57,080
+فبتلاقي المنطقة اللي في منطقة المفصل كلها بيبلش
+
+63
+00:04:57,080 --> 00:05:00,900
+يصير فيها Granulated tissue الشغل التاني
+
+64
+00:05:00,900 --> 00:05:05,960
+Generalized lymphadenopathy تورنهم في الغدد
+
+65
+00:05:05,960 --> 00:05:10,220
+اللينفوية بشكل عام في الجسم بـCertoxemia طيب، إيش
+
+66
+00:05:10,220 --> 00:05:15,490
+الأعراض المصاحبة للـRheumatoid Arthritis؟أول حاجة
+
+67
+00:05:15,490 --> 00:05:22,690
+pain بيبدأ يشكي المريض من ألم بالمفاصل سخونة
+
+68
+00:05:22,690 --> 00:05:28,530
+بالمفصل warmth swelling انتفاخ morning stiffness
+
+69
+00:05:28,530 --> 00:05:33,730
+in the joint صبح المفصل مش قادر يحركه nodule under
+
+70
+00:05:33,730 --> 00:05:38,410
+the skin بتلاقي زي حبيبات تحت الجلد if the disease
+
+71
+00:05:38,410 --> 00:05:44,220
+has progressed لو المرض تطورهتلاقي في الـ X-ray
+
+72
+00:05:44,220 --> 00:05:47,700
+swollen joint capsule and loss of cartilage and
+
+73
+00:05:47,700 --> 00:05:52,040
+bone هتلاقي إنه المفصل صار فيه انتفاخ والـ
+
+74
+00:05:52,040 --> 00:05:55,060
+cartilage بلش يصير فيها تآكل بالإضافة لإنه كمان
+
+75
+00:05:55,060 --> 00:06:03,500
+البون هيصير فيها تآكل نيجي
+
+76
+00:06:03,500 --> 00:06:08,030
+الآن للـ diagnosis of rheumatoid arthritisالصحيح
+
+77
+00:06:08,030 --> 00:06:13,050
+أن روماتويد أرثرايتس يعتبر من الأمراض المعقدة من
+
+78
+00:06:13,050 --> 00:06:17,030
+ناحية الـ diagnosis يعني مافي عندي فحص بحد ذاته
+
+79
+00:06:17,030 --> 00:06:19,910
+أقدر أقول إن هذا الفحص positive معناه الكلام إن
+
+80
+00:06:19,910 --> 00:06:23,970
+هذا مريض روماتويد أرثرايتس هذا negative يعني لأ،
+
+81
+00:06:23,970 --> 00:06:26,290
+يعني حتى الـ Rheumatoid factor اللي إحنا بدنا
+
+82
+00:06:26,290 --> 00:06:32,370
+ناخده اليوم نسبة الدقة فيه 60% يعني في عندي 40% من
+
+83
+00:06:32,370 --> 00:06:34,590
+الناس هيطلع عندهم إما false positive أو false
+
+84
+00:06:34,590 --> 00:06:39,020
+negative result عشان هيكبيعتبر هذا الفحص يعني أو
+
+85
+00:06:39,020 --> 00:06:44,820
+عفوًا هذا المرض بيتم التشخيص لهعن طريق مجموعة من
+
+86
+00:06:44,820 --> 00:06:48,580
+الأشياء مع بعض، يعني مجتمعة مع بعض في عندي
+
+87
+00:06:48,580 --> 00:06:52,360
+Clinical Diagnosis، في عندي Lab Diagnosis، Imaging
+
+88
+00:06:52,360 --> 00:06:57,320
+Features بالتصوير، كل الأشياء هذه مع بعض بتخلي
+
+89
+00:06:57,320 --> 00:07:01,140
+الدكتور يكوّن صورة متكاملة ويقدر يعطي Diagnosis
+
+90
+00:07:01,140 --> 00:07:03,380
+لـRheumatoid Arthritis، بس يعني لو قلت Lab
+
+91
+00:07:03,380 --> 00:07:06,240
+Diagnosis لحاله ما بيتكفي، Clinical Features ما
+
+92
+00:07:06,240 --> 00:07:10,260
+بيتكفي، and so on، لذا نبدأ فيهم واحدة واحدة، أول
+
+93
+00:07:10,260 --> 00:07:14,940
+واحدة الـLab Diagnosis،الـ Lab Diagnosis هنلاقي
+
+94
+00:07:14,940 --> 00:07:19,240
+عند مريض الـ Rheumatoid Arthritis الـ ESR مرتفع
+
+95
+00:07:19,240 --> 00:07:23,960
+الـ Erythrocyte sedimentation rate مرتفع، هاي حاجة
+
+96
+00:07:23,960 --> 00:07:28,820
+الـ CRP يعني في الموضوع الجاي هيكون الـ CRP راح
+
+97
+00:07:28,820 --> 00:07:32,520
+ناخده هذا برتفع في ال inflammation البروتين برتفع
+
+98
+00:07:32,520 --> 00:07:35,840
+في حالة ال inflammation الـ acute inflammation CRP
+
+99
+00:07:35,840 --> 00:07:42,460
+برضه هنلاقيه مرتفع هنعمل CPC برضه للمريضRheumatoid
+
+100
+00:07:42,460 --> 00:07:45,780
+factor هتلاقيه مرتفع هتلاقي الطي ترتاعه فوق
+
+101
+00:07:45,780 --> 00:07:50,460
+التمانية Anti-nuclear antibody ممكن يكون عنده
+
+102
+00:07:50,460 --> 00:07:54,580
+positive أحياناً Anti-cyclic citrulinated peptide
+
+103
+00:07:54,580 --> 00:07:59,990
+and Anti-mutated citrulinated-diminin أثيرأهم واحد
+
+104
+00:07:59,990 --> 00:08:03,070
+يعني أفضل واحد في الفحوصات المخبرية للـ Rheumatoid
+
+105
+00:08:03,070 --> 00:08:07,230
+Arthritis اللي هو الـ Anticyclic Citrulinated
+
+106
+00:08:07,230 --> 00:08:11,690
+Peptide اليوم هو يعتبر فحص حديث وبيعطي Diagnosis
+
+107
+00:08:11,690 --> 00:08:16,730
+جيد للـ Rheumatoid Arthritis لذن هذه مجموعة ال lab
+
+108
+00:08:16,730 --> 00:08:21,670
+test اللي بتنعمل لمريض Rheumatoid Arthritis نيجي
+
+109
+00:08:21,670 --> 00:08:27,000
+للأشياء التانيةنأتي للـ Image زي الـ ultrasound
+
+110
+00:08:27,000 --> 00:08:31,440
+والراديوغرافي والأشياء هذه نشوف إيش بينعمل أول إشي
+
+111
+00:08:31,440 --> 00:08:35,440
+اللي هي الـ RadiographyRadiography اللي هي صورة
+
+112
+00:08:35,440 --> 00:08:39,460
+أشعة بيقولولها ملونة بيحطوا فيها مادة مشعة بتصور
+
+113
+00:08:39,460 --> 00:08:44,360
+المفصل في الـ X-Ray بتعطي شوية تقلق فبتبين تفاصيل
+
+114
+00:08:44,360 --> 00:08:47,740
+المفصل تعتبر الـ First Choice ممكن يصوروا فيها
+
+115
+00:08:47,740 --> 00:08:50,800
+المفاصل كلها بشكل عام الإيدان ال rest اللي فيه
+
+116
+00:08:50,800 --> 00:08:55,200
+تقلبه أي منطقة ممكن تتصور بهذه التقنية الشغلة
+
+117
+00:08:55,200 --> 00:08:59,220
+التانية اللي هي الـ MRI الـ MRI اللي هي الـ
+
+118
+00:08:59,220 --> 00:09:02,390
+Magnetic Resonance Imagingالرنين المغناطيسي اللي
+
+119
+00:09:02,390 --> 00:09:06,650
+احنا بنسميها بشكل عام للـ cervical spine العضام
+
+120
+00:09:06,650 --> 00:09:13,350
+العمود الفقري من جهة الـ cervical region بيبين ان
+
+121
+00:09:13,350 --> 00:09:18,160
+فيها التهاب وفيها تآكلUltrasound، Ultrasound طبعاً
+
+122
+00:09:18,160 --> 00:09:21,680
+بتبين عندي هذه يعني باخد فكرة عن المفصل بياخد
+
+123
+00:09:21,680 --> 00:09:26,200
+الدكتورة فتح فكرة عن الـTendon Sheath عن التغيرات
+
+124
+00:09:26,200 --> 00:09:29,780
+اللي صارت في المفصل، درجة الـVascularization of
+
+125
+00:09:29,780 --> 00:09:32,860
+the synovial membrane and even Erosion يعني حتى
+
+126
+00:09:32,860 --> 00:09:36,980
+التأكل ممكن يبين بالـUltrasound الشغلة أخيرة ممكن
+
+127
+00:09:36,980 --> 00:09:40,920
+نعملها اللي هي الـJoint Aspiration هذا في حالة ما
+
+128
+00:09:40,920 --> 00:09:44,800
+يكون فيه accumulation للـfluidممكن ياخدوا عينة من
+
+129
+00:09:44,800 --> 00:09:47,520
+الصينوفيا الـ Fluid نفسه ويعملوا عليها Gram
+
+130
+00:09:47,520 --> 00:09:51,120
+Stencil Count and Culture بعدين Assessment of
+
+131
+00:09:51,120 --> 00:09:54,340
+Overall Appearance للpatient هذه الأشياء كلها
+
+132
+00:09:54,340 --> 00:09:57,760
+بيعملها الدكتور عشان يعطي في الآخر Diagnosis للـ
+
+133
+00:09:57,760 --> 00:10:06,360
+Rheumatoid Arthritis طيب
+
+134
+00:10:06,360 --> 00:10:09,620
+نيجي للجزئية تاعت الـ Rheumatoid Factor إيش هو الـ
+
+135
+00:10:09,620 --> 00:10:14,480
+Rheumatoid Factor؟الـ Rheumatoid Factor غالباً
+
+136
+00:10:14,480 --> 00:10:20,300
+بنلاقي في حالات Rheumatoid Arthritis هو عبارة عن
+
+137
+00:10:20,300 --> 00:10:25,280
+إيش؟ هو عبارة عن Antibody Antibody لإيش؟ خلّعوا
+
+138
+00:10:25,280 --> 00:10:31,360
+معايا هنا الـ Rheumatoid Factor هذا الـ IgM اللي
+
+139
+00:10:31,360 --> 00:10:40,260
+بالصورة أو هذا الـ IgG هو عبارة عن Antibody يتكون
+
+140
+00:10:40,260 --> 00:10:47,640
+في الجسمللـ FC portion بتاعة الـ IgG ثمان مرة هو
+
+141
+00:10:47,640 --> 00:10:52,160
+عبارة عن Antibody يتكون للـ FC portion بتاعة الـ
+
+142
+00:10:52,160 --> 00:10:58,340
+IgG الموجودة في الجسم قد يكون من النوع IgM أو IgG
+
+143
+00:10:58,340 --> 00:11:04,020
+طيب، لما بتكون Antibody لـ Antibody هيعملوا اتنين
+
+144
+00:11:04,020 --> 00:11:11,150
+Complexes مع بعض ويبدو يترسبوا في المفاصلالترثب
+
+145
+00:11:11,150 --> 00:11:15,370
+هذا في المفاصل هيعمل activation للـ complement
+
+146
+00:11:15,370 --> 00:11:21,230
+وهيعمل عندي type 3 hypersensitivity reaction ويؤدي
+
+147
+00:11:21,230 --> 00:11:25,150
+لـ inflammation يعني immune complexes اترثبت هتعمل
+
+148
+00:11:25,150 --> 00:11:28,770
+complement activation واتنشر في جهاز المناع إنه
+
+149
+00:11:28,770 --> 00:11:31,870
+يبدأ يشتغل ويعمل ال signs المعروفة بتاعة ال
+
+150
+00:11:31,870 --> 00:11:35,530
+inflammation اللي هي التورم والاحمرار والقلم
+
+151
+00:11:35,530 --> 00:11:40,530
+والأعراض المصاحبة للـ rheumatoid arthritisأعيد
+
+152
+00:11:40,530 --> 00:11:45,710
+تاني إذا هو Antibody للـ FC portion بتاعت الـ IgG
+
+153
+00:11:45,710 --> 00:11:49,270
+Antibody للـ Antibody الموجودة بالجسم بيعمل immune
+
+154
+00:11:49,270 --> 00:11:53,510
+complexes بتترسب بالمفصل و بتكون harmful للمفصل
+
+155
+00:11:53,510 --> 00:12:00,890
+بتكون مؤذية و ضارة طيب نيجي للفحص بتاع الـ
+
+156
+00:12:00,890 --> 00:12:03,930
+Rheumatoid Factor The test for rheumatoid factor
+
+157
+00:12:03,930 --> 00:12:06,870
+may be ordered when a person has signs and
+
+158
+00:12:06,870 --> 00:12:10,310
+symptoms of rheumatoid arthritisيعني اليوم الدكتور
+
+159
+00:12:10,310 --> 00:12:13,870
+أول ما واحد بيروح يشك من الوجع في المفاصل من
+
+160
+00:12:13,870 --> 00:12:18,470
+الحاجات اللي بيعملوها عادة بطلبوله CBC و ESR
+
+161
+00:12:18,470 --> 00:12:23,810
+بطلبوله RF و CRB و Uric Acid هذه الحاجات يعني
+
+162
+00:12:23,810 --> 00:12:27,850
+بيشكوا أنه مثلا يكون فيه Gout فيه Uric Acid مرتش
+
+163
+00:12:27,850 --> 00:12:31,370
+في المفاصل بيعملوا روماتود و بطلبوا ال ASOT راح
+
+164
+00:12:31,370 --> 00:12:35,410
+ناخده لقدام شوية يعني هم بتدرجوا حسب الأعراض بيرجح
+
+165
+00:12:35,410 --> 00:12:39,620
+مين يطلب قبل التانيإذن من الفحوصات اللي بتنتلب
+
+166
+00:12:39,620 --> 00:12:43,840
+نقول الـ RF بقولك
+
+167
+00:12:43,840 --> 00:12:47,620
+إنه لو طلع معاك الـ RF Negative لكن أعراض الـ
+
+168
+00:12:47,620 --> 00:12:51,400
+Rheumatoid Arthritis موجودة ممكن ينطلب يعني بقي
+
+169
+00:12:51,400 --> 00:12:54,960
+ممكن يكون الـ Titer تاع واطي و بعد فترة يرتفع
+
+170
+00:12:54,960 --> 00:12:59,120
+فممكن الدكتور يطلبه بعد فترة كمان مرة إذن لو طلع
+
+171
+00:12:59,120 --> 00:13:02,200
+معايا Negative في المرة الأولى مع استمرار الأعراض
+
+172
+00:13:02,200 --> 00:13:06,880
+بنعيد الـ Rheumatoid Factorوغالبا يعني إذا في
+
+173
+00:13:06,880 --> 00:13:12,200
+روماتويد أرثرايتس ممكن يرجع يعطيني Positive في
+
+174
+00:13:12,200 --> 00:13:16,680
+عندي Acyclic Citrulinated Peptide هذه برضه ممتازة
+
+175
+00:13:16,680 --> 00:13:19,360
+في الـ Diagnosis هناخد عنها كمان شوية بالتفصيل
+
+176
+00:13:19,360 --> 00:13:24,760
+طبعا هنا زي ما بقولك ممكن ينطلب معاه أشياء تانية
+
+177
+00:13:24,760 --> 00:13:27,140
+زي الـ Anti-Nuclear Antibody حاجات اللي هي علاقة
+
+178
+00:13:27,140 --> 00:13:31,860
+بالـ Autoimmune Diseases ممكن Markers للإنفلامات
+
+179
+00:13:31,860 --> 00:13:36,480
+زي CRPو الـ ESR و الـ CBC يعني هذه أشياء روتين
+
+180
+00:13:36,480 --> 00:13:39,120
+اللي بتنطلب حتى الواحد لما بروح بشك من مفاصلة و
+
+181
+00:13:39,120 --> 00:13:47,660
+بطلبوله الحاجات هذه بشكل روتيني نيجي
+
+182
+00:13:47,660 --> 00:13:51,700
+للـ Principle للـ Rheumatoid Factor بتاعة الفحص
+
+183
+00:13:51,700 --> 00:13:56,020
+الآن احنا من الأساس قلنا هو الـ Rheumatoid Factor
+
+184
+00:13:56,020 --> 00:14:02,190
+عبارة عن Antibody صح؟ Antibody لإيش؟الـ IGG للـ
+
+185
+00:14:02,190 --> 00:14:06,670
+Antibodies أن هو عبارة عن Anti-antibody فأقفل بدي
+
+186
+00:14:06,670 --> 00:14:11,850
+أجيب الـ Antibody هذا اللي هو ضده يعني كأني بدي
+
+187
+00:14:11,850 --> 00:14:17,050
+أجيب IGG وأحمله على حاجة بحيث أنه يتفاعل معاها
+
+188
+00:14:17,050 --> 00:14:22,790
+ويعمل Agglutination خليني أشوف ونشوف الخلافات في
+
+189
+00:14:22,790 --> 00:14:25,550
+تسمية الفحص يعني هل هو Passive ولا Reverse Passive
+
+190
+00:14:25,550 --> 00:14:30,370
+خليني أخد بالتفصيل حبة حبةأول اشي بجيب Latex
+
+191
+00:14:30,370 --> 00:14:35,790
+Particles حبيبات الـ Latex أو شيب Red Cells خلايا
+
+192
+00:14:35,790 --> 00:14:43,370
+RBCs من شيب في هذه الحالة بسميه Rosular Cell عفواً
+
+193
+00:14:43,370 --> 00:14:49,070
+وسواء جبت Latex Particles أو الـRBCs بحمل عليها
+
+194
+00:14:49,070 --> 00:14:53,930
+الـHuman Immunoglobulin اش بحمل عليها Human
+
+195
+00:14:53,930 --> 00:15:00,470
+Immunoglobulin طبعاًبضيف الـ Particles على عينة
+
+196
+00:15:00,470 --> 00:15:04,110
+الـ Serum اللي عندي إذا أعطتني Agglutination معنى
+
+197
+00:15:04,110 --> 00:15:08,110
+الكلام إنه الـ Antibody موجود واتفاعل مع الـ Latex
+
+198
+00:15:08,110 --> 00:15:10,770
+Particles مع الـ Antibody اللي على سطح الـ Latex
+
+199
+00:15:10,770 --> 00:15:17,410
+Particles وأعطاني Positive طيب، هلقيت في عندى هنا
+
+200
+00:15:17,410 --> 00:15:24,240
+جدالية صغيرة بتصيرإذا كنتوا فاكرين احنا سمينا الـ
+
+201
+00:15:24,240 --> 00:15:28,680
+Passive Agglutination قولنا فيه منه نوعين في عندي
+
+202
+00:15:28,680 --> 00:15:33,980
+Passive و في عندي Reverse Passive إذا أنا حملت الـ
+
+203
+00:15:33,980 --> 00:15:38,120
+Antigen على الـ Latex Particles بسميه Passive إذا
+
+204
+00:15:38,120 --> 00:15:42,420
+حملت الـ Antibody بسميه Reverse Passive طب أنا هذا
+
+205
+00:15:42,420 --> 00:15:46,520
+بعتبره Antigen ولا بعتبره Antibody؟ أنا عارفة في
+
+206
+00:15:46,520 --> 00:15:49,100
+ناس هتقول Antigen في ناس هتقول Antibody في ناس
+
+207
+00:15:49,100 --> 00:15:55,890
+هتقول Antigenعشان هيك الفحص هذا يعني مش صح إنك
+
+208
+00:15:55,890 --> 00:15:59,570
+تنسقلي عنه هل هو Passive ولا Reverse Passive، ليش؟
+
+209
+00:15:59,570 --> 00:16:04,630
+لأنه هو أساساً المحمل Antibody، صح؟ لأن أحنا من
+
+210
+00:16:04,630 --> 00:16:08,150
+الأساس قلنا إحنا حملنا Human Immunoglobulin لكن
+
+211
+00:16:08,150 --> 00:16:12,250
+لأن اللي أنا مفحصه Antibodyبدي أعتبر هذا Antigen
+
+212
+00:16:12,250 --> 00:16:16,750
+يعني كأنه Antigen فبالتالي هو فعليًا Antibody لكن
+
+213
+00:16:16,750 --> 00:16:20,270
+ممكن نتعامل معاه كـ Antigen يعني حتى إحنا لو شوفنا
+
+214
+00:16:20,270 --> 00:16:23,610
+الرسمة هذه بتقولك Antigen المحمل طب إيش الـ
+
+215
+00:16:23,610 --> 00:16:27,030
+Antigen هذا طبيعته؟ Antibody فبالتالي هنا الجدلية
+
+216
+00:16:27,030 --> 00:16:30,350
+لن تنتهي يعني ممكن أسميه Passive وممكن أسميه
+
+217
+00:16:30,350 --> 00:16:33,550
+Reverse Passive ليهاش تقولوا في ناس هتعتبر أن الـ
+
+218
+00:16:33,550 --> 00:16:37,090
+Antibody هذا طالما هو بيتفاعل مع Antibody بالفحص
+
+219
+00:16:37,090 --> 00:16:41,070
+كـ Antigenعشان هيك يعني مش هتنسيق اللي هو Passive
+
+220
+00:16:41,070 --> 00:16:43,870
+أو Reverse Passive ممكن اعتبره Passive وممكن في
+
+221
+00:16:43,870 --> 00:16:47,130
+أماكن تانية اتلاقيه يعني مكتوب عنه انه Reverse
+
+222
+00:16:47,130 --> 00:16:53,390
+Passive فهمنا لياش واضحة تمام نيجي لطريقة الشغل
+
+223
+00:16:53,390 --> 00:16:58,270
+العينة اللي أنا باخدها Serum لا يجوز بأي حال من
+
+224
+00:16:58,270 --> 00:17:01,570
+الأحوال أني أخد بلازمة لأن البلازمة فيها
+
+225
+00:17:01,570 --> 00:17:05,930
+Fibrinogen والـFibrinogen for sure هيعطيني مع
+
+226
+00:17:05,930 --> 00:17:09,630
+الـRheumatoid Factor Positiveعشان هيك منفعش أخد
+
+227
+00:17:09,630 --> 00:17:13,870
+بلازما خالص باخد serum أو sinovie ال fluid sample
+
+228
+00:17:13,870 --> 00:17:22,210
+الآن كيف طريقة الفحص هذا بعمله في عندي slide slide
+
+229
+00:17:22,210 --> 00:17:26,910
+هذه يعني بختارها إما سودة أو بيضة حسب لون ال
+
+230
+00:17:26,910 --> 00:17:30,330
+reagent إذا كان ال reagent أبيض بختار خلفية سودة
+
+231
+00:17:30,750 --> 00:17:33,910
+إذا كان الـ Reagent أزرق أو أي لون تاني بختار
+
+232
+00:17:33,910 --> 00:17:37,450
+خلفية بيضة عشان هي خلفية تساعد على يعني بختار
+
+233
+00:17:37,450 --> 00:17:41,950
+خلفية مساعدة معاكسة لللون تساعدني على أني أشوف الـ
+
+234
+00:17:41,950 --> 00:17:46,670
+agglutination باخد directly one drop من الـ sample
+
+235
+00:17:46,670 --> 00:17:49,290
+على one drop من الـ reagent طبعا ال drop في
+
+236
+00:17:49,290 --> 00:17:52,330
+السيرولوجي خدوها قاعدة لما أقولك one drop one drop
+
+237
+00:17:52,330 --> 00:17:55,970
+ال drop عبارة عن خمسين microliter هذه خديها
+
+238
+00:17:55,970 --> 00:18:00,970
+القاعدةباخد one drop مع one drop بعمل mixing وبشوف
+
+239
+00:18:00,970 --> 00:18:04,850
+النتيجة طبعا إذا ظهر agglutination يعني positive
+
+240
+00:18:04,850 --> 00:18:11,370
+إذا ما ظهر agglutination يعني إيش؟ negative طيب
+
+241
+00:18:11,370 --> 00:18:18,650
+هنا في عندي ملاحظة مهمة في الشغل القد في ال
+
+242
+00:18:18,650 --> 00:18:23,050
+rheumatoid factor لو أنا أجيت عملت أول واحدة وطلعت
+
+243
+00:18:23,050 --> 00:18:28,260
+معايا positive ال title تاعة هيكون واحدطبعاً هذه
+
+244
+00:18:28,260 --> 00:18:32,720
+مابعتبرهاش positive لازم يكون الـ titer أكتر من 8
+
+245
+00:18:32,720 --> 00:18:37,440
+عشان أعتبرها positive فإيش أنا بروح بعمل لازم أعمل
+
+246
+00:18:37,440 --> 00:18:40,660
+منها serial dilution يعني باخد من العينة يا بنات
+
+247
+00:18:40,660 --> 00:18:49,100
+في تيوب بعمل serial dilution 1 ل 2 1 ل 4 1 ل 8 1 ل
+
+248
+00:18:49,100 --> 00:18:54,460
+16أو 1 لـ 32 يعني قد صار عندي مثلا خمسة كيوبات أنا
+
+249
+00:18:54,460 --> 00:18:56,580
+عاملة فيهم cereal dilution بطريقة الـ cereal
+
+250
+00:18:56,580 --> 00:18:59,260
+dilution اللي حكينا عنها في الأسبوع الماضي هدول في
+
+251
+00:18:59,260 --> 00:19:02,580
+قنابيب هك و هحطهم على الراك و بعمللهم dilution بس
+
+252
+00:19:02,580 --> 00:19:06,080
+يرقاش أخد من أول واحدة اللي هي 1 ل 2 أخد منها
+
+253
+00:19:06,080 --> 00:19:09,800
+خمسين مايكرون أحط على ال slide هادي و أحط عليها
+
+254
+00:19:09,800 --> 00:19:13,820
+خمسين مايكرون من ال reaction و أعمل mixing و أشوف
+
+255
+00:19:13,940 --> 00:19:17,400
+إذا كانت positive بدي أعمل اللي بعدها بنفس الطريقة
+
+256
+00:19:17,400 --> 00:19:22,180
+50 micron من الـ tube اللي تركيزها 1 ل 4 على 50
+
+257
+00:19:22,180 --> 00:19:25,800
+micron من الـ region لغاية ما تعطيني negative
+
+258
+00:19:25,800 --> 00:19:31,980
+أضلني أعمل لغاية ما تعطيني negative الآن بعتبرها
+
+259
+00:19:31,980 --> 00:19:37,520
+positive بعتبرها positive إذا الـ titer زاد عن 8
+
+260
+00:19:37,520 --> 00:19:43,330
+لغاية 8 فما فوق بعتبرها positive أقل من 8بعتبرهاش
+
+261
+00:19:43,330 --> 00:19:46,870
+Positive يعني بيبقى False Positive تمام يا بنات؟
+
+262
+00:19:46,870 --> 00:19:52,530
+إذا الـ Titer لازم ينعمل في الفحصات السيرولوجية
+
+263
+00:19:52,530 --> 00:19:56,390
+عنا هنا في الـ Synovia في الـ Rheumatoid Factor
+
+264
+00:19:56,390 --> 00:20:00,530
+لازم الـ Titer أعمله ويزيد عن 8 عشان أعتبر إن
+
+265
+00:20:00,530 --> 00:20:04,630
+النتيجة Positive لو طلعت عندي مثلا الـ Titer 8
+
+266
+00:20:04,630 --> 00:20:10,920
+يندي طريقتين للتعبير عن النتيجة إما بقول 8الـ
+
+267
+00:20:10,920 --> 00:20:15,800
+Titer 8 أو بعبّر عنه بالـ units per milliliter طيب
+
+268
+00:20:15,800 --> 00:20:21,460
+كيف أحول الـ Titer إلى units per milliliter؟ في
+
+269
+00:20:21,460 --> 00:20:26,160
+رقم بيكون يعطيني ياق في الـ kit الرقم هذا هو عبارة
+
+270
+00:20:26,160 --> 00:20:29,720
+عن تركيز الـ Positive Control ممكن يقول 6 مثلا
+
+271
+00:20:29,720 --> 00:20:36,180
+فإذا قال 6 بقول لو طلع عندي الـ Titer 8 بضرب 8 في
+
+272
+00:20:36,180 --> 00:20:43,480
+6 بطلع عندي التركيزunit per milliliter 6×8 48 واضح
+
+273
+00:20:43,480 --> 00:20:46,980
+إذا في انت طريقتين للتعبير عن النتيجة إما بالـ
+
+274
+00:20:46,980 --> 00:20:51,580
+titer وإما بال unit فبكيد بدي أحول من titer ل unit
+
+275
+00:20:51,580 --> 00:20:57,220
+بضرب في رقم هذا الرقم بيكون يعطيني ياف ال kit هو
+
+276
+00:20:57,220 --> 00:21:01,940
+عبارة عن إيش تركيز ال positive control مثلا كان
+
+277
+00:21:01,940 --> 00:21:10,550
+كاتب عليه 6 فبدي أضرب في 6 6×8 48 unitبار ملي لتر
+
+278
+00:21:10,550 --> 00:21:14,430
+ان شاء الله يعني بتتاح الظروف و بنرجع و هذا الشغل
+
+279
+00:21:14,430 --> 00:21:18,310
+كله بنشتغله و بنشوف كيف بنعمل الـ Serial Dilution
+
+280
+00:21:18,310 --> 00:21:24,630
+و كيف بنشتغل هذا على أرض الواقع اللي حكينا عنه قبل
+
+281
+00:21:24,630 --> 00:21:30,190
+بشوية أن الفحص كان باعتمد الـ Antigen أو الـ
+
+282
+00:21:30,190 --> 00:21:32,650
+Antibody اللي حكينا عنه Antibody و أحيانا تتعاملوا
+
+283
+00:21:32,650 --> 00:21:36,960
+معاه كـ Antigen محمل على Latex Particlesلكن في
+
+284
+00:21:36,960 --> 00:21:41,460
+طريقة تانية ان نحمل الـ Antibody هذا على shape of
+
+285
+00:21:41,460 --> 00:21:47,840
+human red cells وهنا بسميه Rosular نفس الفكرة ونفس
+
+286
+00:21:47,840 --> 00:21:51,480
+الاشي بس يعني ايش ال particles المحمل عليها الـ
+
+287
+00:21:51,480 --> 00:21:56,920
+Antibody هنا عندي RBCs هنا بقولك الـ Sensitized
+
+288
+00:21:56,920 --> 00:22:00,580
+RBCs بتكون هذا الفحص يعتبر more sensitive than
+
+289
+00:22:00,580 --> 00:22:05,380
+latexيعني ممكن الـ Latex أحيانًا يعطيني Negative
+
+290
+00:22:05,380 --> 00:22:08,720
+لكن هذا يعطيني Positive ليش؟ لأن هذا More
+
+291
+00:22:08,720 --> 00:22:12,220
+Sensitive وبتفاعل مع التركيزات القليلة من الـ
+
+292
+00:22:12,220 --> 00:22:17,260
+Antibody بقوة أفضل من الـ Latex Particles الاتنين
+
+293
+00:22:17,260 --> 00:22:22,840
+متاحين والاتنين ممكن نشتغل عليهم بنفس الطريق طيب،
+
+294
+00:22:22,840 --> 00:22:27,340
+الآن لو طلع معايا هذا الفحص Positive على إيش بدل؟
+
+295
+00:22:27,340 --> 00:22:33,170
+يعني إحنا بنربط الآن النتيجةمع الـ Symptoms و الـ
+
+296
+00:22:33,170 --> 00:22:38,170
+Clinical History بقولك إذا كانت أعطاني هذا الفحص
+
+297
+00:22:38,170 --> 00:22:43,810
+Positive وكان المريض هذا عنده Symptoms و Size للـ
+
+298
+00:22:43,810 --> 00:22:48,570
+Rheumatoid Arthritis وجود RF Positive بمستوى يعني
+
+299
+00:22:48,570 --> 00:22:52,190
+مرتفع أو بتايتر مرتفع غالباً بيرجح إنه حالة
+
+300
+00:22:52,190 --> 00:22:58,900
+Rheumatoid Arthritis وعادة تتناسب الأعراضوالـ
+
+301
+00:22:58,900 --> 00:23:02,320
+Prognosis مع نسبة الـ RF يعني كل ما كان الـ RF
+
+302
+00:23:02,320 --> 00:23:06,960
+أعلى كل ما كانت الأعراض أشد حدة وكان المرض الـ
+
+303
+00:23:06,960 --> 00:23:12,460
+Prognosis له أسوأ لكن بقولك في ناس يعني تقريباً 20
+
+304
+00:23:12,460 --> 00:23:15,060
+% من الناس بيكون عندهم الأعراض بيكون عندهم
+
+305
+00:23:15,060 --> 00:23:18,680
+Rheumatoid Arthritis لكن بيعطوني False Negative
+
+306
+00:23:18,680 --> 00:23:23,560
+Result في هذه الحالات في عنا فحص تاني اللي هو Anti
+
+307
+00:23:23,560 --> 00:23:27,400
+-CCBAntibody عبارة عن Antibody بيعطيني Positive
+
+308
+00:23:27,400 --> 00:23:30,300
+وبيعمل confirmation للـ Rheumatoid Arthritis
+
+309
+00:23:30,300 --> 00:23:38,500
+خلّينا نشوف بعد ذلك إيش هو Anti-CCP طيب
+
+310
+00:23:38,500 --> 00:23:44,940
+هلقيت بقولك الـ Positive RF Result ممكن يكون في
+
+311
+00:23:44,940 --> 00:23:49,620
+قريبا في 5% من ال individuals وفي مرضى في عندهم
+
+312
+00:23:49,620 --> 00:23:53,180
+أعراض تانية ممكن يعطيكي RF PositiveJogreen
+
+313
+00:23:53,180 --> 00:23:57,480
+Syndrome هذا عبارة عن مرض autoimmune disease بيأثر
+
+314
+00:23:57,480 --> 00:24:01,520
+على .. بيعمل جفاف في الـ mucous membrane ويله
+
+315
+00:24:01,520 --> 00:24:04,340
+أعراض معينة في الـ lobes، في حالات الـ
+
+316
+00:24:04,340 --> 00:24:07,860
+endocarditis في حالات الـ tuberculosis، syphilis،
+
+317
+00:24:07,860 --> 00:24:12,480
+HIV، hepatitis infectious mononucleosis، بعض أنواع
+
+318
+00:24:12,480 --> 00:24:15,580
+الـ cancers زي الليوكيميا والـ multiple myeloma في
+
+319
+00:24:15,580 --> 00:24:18,340
+بعض الـ parasitic infections في بعض الـ disease زي
+
+320
+00:24:18,340 --> 00:24:26,620
+الـ liver, kidney, lung diseaseهذه كلها حالات ممكن
+
+321
+00:24:26,620 --> 00:24:31,660
+ألاقي إن الـ RF فيها ارتفع وعطاني positive result
+
+322
+00:24:31,660 --> 00:24:35,420
+لكن non-specific يعني ماهياش rheumatoid arthritis
+
+323
+00:24:35,420 --> 00:24:40,260
+طبعا هنا بقولك ملاحظة الـ RF is not used to
+
+324
+00:24:40,260 --> 00:24:43,580
+diagnose or monitor these other conditions يعني
+
+325
+00:24:43,580 --> 00:24:47,100
+أنا لو طلعت معايا الـ RF positive في واحد من هدول
+
+326
+00:24:47,450 --> 00:24:51,190
+بروحش بأستخدمه عشان أعمل مثلا Hepatitis بروحش
+
+327
+00:24:51,190 --> 00:24:54,410
+أستخدم الـ RF عشان أعمل follow-up للـ Hepatitis لأ
+
+328
+00:24:54,410 --> 00:24:58,370
+يعني ممكن يرتفع وينزل بشكل عشوائي مش منتظم في هذا
+
+329
+00:24:58,370 --> 00:25:00,830
+ال disease يعني ما أستخدمه لا للمتابعة ولا لل
+
+330
+00:25:00,830 --> 00:25:04,290
+diagnosis بس هو بقولك ممكن تكون كinterfering
+
+331
+00:25:04,290 --> 00:25:13,270
+factors مع النتيجة تبعه هنا
+
+332
+00:25:13,270 --> 00:25:18,580
+فينا ملاحظةIf the result is positive then do
+
+333
+00:25:18,580 --> 00:25:21,200
+serial dilution to determine the accurate
+
+334
+00:25:21,200 --> 00:25:25,180
+titration of RF in serum هذه قلناها إن أنا لازم
+
+335
+00:25:25,180 --> 00:25:28,480
+أعمل titration عشان أحدد الـtitration تاع الـRF
+
+336
+00:25:28,480 --> 00:25:32,380
+Semi-quantitative method قلتلكم كيف بعمل dilution
+
+337
+00:25:32,380 --> 00:25:37,640
+بالقنابيب وباخد من القنابيب هادي وبشتغل الـRF عشان
+
+338
+00:25:37,640 --> 00:25:43,260
+أشوف الـtitration صحيح للعينة طيب الـnegative
+
+339
+00:25:43,260 --> 00:25:46,610
+resultfrom the direct agglutination doesn't rule
+
+340
+00:25:46,610 --> 00:25:50,110
+out rheumatoid arthritis and positive result is
+
+341
+00:25:50,110 --> 00:25:53,550
+not specific for rheumatoid arthritis هنا بقولك
+
+342
+00:25:53,550 --> 00:25:58,230
+الـ negative لا تستثني والـ positive مش مؤكدة هنا
+
+343
+00:25:58,230 --> 00:26:01,650
+بقولك مثال على الـ negative لبروزان فينومينا
+
+344
+00:26:01,650 --> 00:26:06,090
+أحيانا يا بنات فاكرين لما رسمتلكم الجدول قلتلكم
+
+345
+00:26:06,090 --> 00:26:10,050
+لازم تبقى كمية الانتجن متناسبة مع كمية الانتيبودي
+
+346
+00:26:10,050 --> 00:26:13,390
+عشان يعطيكي positiveإذا كانت كمية الـ Antibody
+
+347
+00:26:13,390 --> 00:26:16,190
+عالية هيعطيكي False Negative وإذا كانت كمية الـ
+
+348
+00:26:16,190 --> 00:26:20,230
+Antigen عالية هيعطيكي False Negative فبالتالي
+
+349
+00:26:20,230 --> 00:26:25,930
+أحياناً تبقى تركيز الـ Antibodies عالي جداً ولمّا
+
+350
+00:26:25,930 --> 00:26:29,210
+أجي أشتغل مباشرة منه مابيعطيكيش Positive حتى و هو
+
+351
+00:26:29,210 --> 00:26:33,770
+موجود، ليش؟ لأنه في عندنا ظاهرة بيسموها Brow zone
+
+352
+00:26:33,770 --> 00:26:37,090
+phenomena لما يبقى الـ Title على الـ Antibody عالي
+
+353
+00:26:37,090 --> 00:26:41,860
+هيعطيكي False Negativeلقيت لما انت تيجي تعمل الـ
+
+354
+00:26:41,860 --> 00:26:45,980
+Delution أول تيتر و تاني تيتر ممكن يعطيك Negative
+
+355
+00:26:45,980 --> 00:26:50,160
+لكن بعد هيك يبلش يعطيك Positive إذا ظهرت عندك هذه
+
+356
+00:26:50,160 --> 00:26:54,860
+الشغلة بدل على إنه الـ Titer عالي كتير وظهرت عندي
+
+357
+00:26:54,860 --> 00:27:00,800
+لبروزون فينومينة هي اللي منعت الـ Antibody أنه
+
+358
+00:27:00,800 --> 00:27:08,320
+يتفاعل بشكل صحيح طيب إيش معنى الكلام؟ معنى الكلام
+
+359
+00:27:08,320 --> 00:27:14,610
+أنهسواء طلعت معاك العينة Positive أو Negative
+
+360
+00:27:14,610 --> 00:27:19,150
+المفروض تعمليها Dilution وتشوف الـTiter تاعها لأن
+
+361
+00:27:19,150 --> 00:27:21,990
+Positive عرفنا ليش، عشان نشوف الـTiter طب Negative
+
+362
+00:27:21,990 --> 00:27:24,910
+طب هو ممكن يبقى False Negative الـTiter عالي عشان
+
+363
+00:27:24,910 --> 00:27:28,450
+هيك ماعطانيش Positive فلما باجي بعمل Dilution
+
+364
+00:27:28,450 --> 00:27:32,910
+للـNegative Sample وتعطيني Positive بعد هيك متأكد
+
+365
+00:27:32,910 --> 00:27:35,570
+من وجود لبرزان الـPhenomena
+
+366
+00:27:41,410 --> 00:27:45,450
+إيش في عندي بعض الـinterfering factors زي بقولك لو
+
+367
+00:27:45,450 --> 00:27:48,370
+كانت الـlibids أو الـcryoglobulin عالية ممكن
+
+368
+00:27:48,370 --> 00:27:52,890
+تعطينا false positive ال IGG عالية ممكن تعطي false
+
+369
+00:27:52,890 --> 00:27:57,030
+positive لو كان في عندنا activated complement برضه
+
+370
+00:27:57,030 --> 00:28:03,330
+ممكن تعطي false positive results نيجي
+
+371
+00:28:03,330 --> 00:28:08,030
+لاللي هو الفحص الأهم في تشخيص الـRheumatoid
+
+372
+00:28:08,030 --> 00:28:12,120
+Arthritisاللي هو Cyclic Citrulinated Peptide
+
+373
+00:28:12,120 --> 00:28:16,580
+Antibody هذا عادة بنطلب صار يعني لما بيطلع عندنا
+
+374
+00:28:16,580 --> 00:28:19,060
+الـ Rheumatoid Factor Positive بيروح و بطلبوا الـ
+
+375
+00:28:19,060 --> 00:28:22,860
+Cyclic Citrulinated Peptide هو فحص لسه مش يعني
+
+376
+00:28:22,860 --> 00:28:27,900
+كتير يعني مش كتير معروف أو مابينطلبش على شكل واسع
+
+377
+00:28:27,900 --> 00:28:31,880
+أو على نطاق واسع بس الصحيح هو كتير أفضل من الـ RF
+
+378
+00:28:31,880 --> 00:28:36,000
+بنطلب معاه عشان يحدد الـ severity للـ disease و
+
+379
+00:28:36,000 --> 00:28:39,780
+الـ prognosisفي أشياء تانية حكينا إنها بتنطلب زي
+
+380
+00:28:39,780 --> 00:28:43,200
+الـ ESR والـ C-Reactive Protein خلّينا نشوف الـ
+
+381
+00:28:43,200 --> 00:28:47,180
+Cyclic Citrulinated Peptide هذا عبارة عن إيه؟ هذا
+
+382
+00:28:47,180 --> 00:28:55,640
+عبارة عن Autoantibody تمام؟ لا إيش Directed
+
+383
+00:28:55,640 --> 00:28:59,200
+against Cyclic Citrulinated Peptide خلّينا نشوف
+
+384
+00:28:59,200 --> 00:29:05,800
+إيش هي الـ Cyclic Citrulinated Peptide الـ
+
+385
+00:29:05,800 --> 00:29:08,970
+Cyclicيعني الـ Cyclic Citrullinated Antibody أو
+
+386
+00:29:08,970 --> 00:29:11,670
+Anticyclic Citrullinated Peptide Antibody كيف
+
+387
+00:29:11,670 --> 00:29:15,570
+بتكون في الجسم و ليش بتكون؟ هلقيت احنا عارفين الـ
+
+388
+00:29:15,570 --> 00:29:18,510
+Metabolism للـ Amino Acids في عندي الـ Arginine
+
+389
+00:29:18,510 --> 00:29:22,250
+نتيجة الـ Metabolism بتاعه بتكون عندنا الـ
+
+390
+00:29:22,250 --> 00:29:25,450
+Citrulline ال Citrulline برضه عبارة عن Amino Acid
+
+391
+00:29:25,450 --> 00:29:28,910
+تاني هلقيت بقولك في مرض الـ Rheumatoid Arthritis
+
+392
+00:29:29,630 --> 00:29:34,630
+واجدوا إن الـ «سيترولين» بتحول أو بتكون على وثيرة
+
+393
+00:29:34,630 --> 00:29:39,890
+عالية يعني بتكون بكمية كبيرة الآن تكون الـ
+
+394
+00:29:39,890 --> 00:29:46,370
+«سيترولين» بهذه الطريقة أو بهذه الكمية بعمل بعض
+
+395
+00:29:46,370 --> 00:29:49,450
+الـ «تغييرات» زي الـ Denaturation في الـ Protein
+
+396
+00:29:49,450 --> 00:29:54,370
+Structure التغييرات هذه في الـ Protein Structure
+
+397
+00:29:54,960 --> 00:29:59,360
+بتخلّي الجسم يكون Antibodies للـ «سترولين» Auto
+
+398
+00:29:59,360 --> 00:30:04,220
+-antibody للـ «سترولين» طبعاً الـ «سترولين» أحد
+
+399
+00:30:04,220 --> 00:30:06,520
+الـ «جاينت بروتين» عشان إيه يسموه «cyclic
+
+400
+00:30:06,520 --> 00:30:09,460
+citrulinated peptide» إذن هو عبارة عن Antibody
+
+401
+00:30:09,460 --> 00:30:12,740
+تكون قبلش اتكون مع أن البروتين طبيعي لأن الـ
+
+402
+00:30:12,740 --> 00:30:17,320
+«سترولين» ارتفع وعمل الـ «denaturation» للبروتين
+
+403
+00:30:17,320 --> 00:30:20,960
+أو تغير الـ «structure» البسيط بتاع البروتين فتعرف
+
+404
+00:30:20,960 --> 00:30:26,170
+على الجسم على إنه Foreign وكون له Antibodiesطبعاً
+
+405
+00:30:26,170 --> 00:30:28,710
+هذه كتير بتساعد في الـ Diagnosis للـ Rheumatoid
+
+406
+00:30:28,710 --> 00:30:32,970
+Arthritis و بتدل على الـ Severity أو الـ Prognosis
+
+407
+00:30:32,970 --> 00:30:37,410
+للدزيز طيب
+
+408
+00:30:37,410 --> 00:30:41,150
+الآن نشوف النتائج تاعتنا على إيش ممكن تدل يعني لو
+
+409
+00:30:41,150 --> 00:30:45,770
+طلع عندي التنين positive الـ CCP والـ RF طلعوا
+
+410
+00:30:45,770 --> 00:30:51,010
+الإتنين positive هذا معنى الكلام إن هذا مريض بالـ
+
+411
+00:30:51,010 --> 00:30:54,610
+Rheumatoid Arthritis وغالباً المرض عنده
+
+412
+00:30:54,610 --> 00:31:00,030
+Progressiveوهيكون Severe و الـ Prognosis لإله يعني
+
+413
+00:31:00,030 --> 00:31:04,910
+هيكون مش بسيط، هيكون سيئة طيب لو كان المريض
+
+414
+00:31:04,910 --> 00:31:10,470
+Positive للـ CCP و Negative للـ RF أو ال عنده Low
+
+415
+00:31:10,470 --> 00:31:15,490
+Level من اتنين هذا بيدل على إنه مريض Rheumatoid
+
+416
+00:31:15,490 --> 00:31:19,690
+Arthritis لكن Early Stage لسه الـ Title للـ
+
+417
+00:31:19,690 --> 00:31:23,590
+Antibodies ما ارتفعشلو بعد فترة إيجيني عندنا
+
+418
+00:31:23,590 --> 00:31:27,930
+هنلاقيه مرتفع وهنلاقي إن الشخص هذا عنده قابلية إنه
+
+419
+00:31:27,930 --> 00:31:32,350
+يكون روماتويد أرثريتس طيب لو كان Negative للـ CCP
+
+420
+00:31:32,350 --> 00:31:36,410
+و Positive للـ RF نتوقع إنه يكون مش روماتويد
+
+421
+00:31:36,410 --> 00:31:40,090
+أرثريتس ممكن يكون أي interfering factor أو
+
+422
+00:31:40,090 --> 00:31:45,940
+inflammation أعطاني Positive RF طيبلو كان الشخص
+
+423
+00:31:45,940 --> 00:31:49,300
+Negative Leptinane معنى الكلام إنه ما عنده
+
+424
+00:31:49,300 --> 00:31:53,440
+روماتويد أرثرايتس ولا هيكون روماتويد أرثرايتس تمام
+
+425
+00:31:53,440 --> 00:31:57,780
+هك؟ يعني خلاصة الكلام إنه أفضل إشي في ال diagnosis
+
+426
+00:31:57,780 --> 00:32:03,840
+الـCCB، Anti-CCB زي
+
+427
+00:32:03,840 --> 00:32:07,680
+ما قلنا الـAnti-CCB هو فحص إلى حد ما حديث ومش كتير
+
+428
+00:32:07,680 --> 00:32:13,810
+منتشر لكن الصحيح هو المفروض الآن ينطلب باستمرارمع
+
+429
+00:32:13,810 --> 00:32:17,610
+الـ Rheumatoid factor لأنه more specific من الـ
+
+430
+00:32:17,610 --> 00:32:21,650
+Rheumatoid factor وبيعطيني نتائج أفضل الـ CCP
+
+431
+00:32:21,650 --> 00:32:25,290
+Antibody مابيعطيش مع الـ Autoimmune disease الأخرى
+
+432
+00:32:25,290 --> 00:32:29,190
+false positive زي الـ RF مابيعمل الـ RF شفنا قائمة
+
+433
+00:32:29,190 --> 00:32:32,930
+طويلة من الأمراض بيعطي معاها positive بينما هذا لأ
+
+434
+00:32:32,930 --> 00:32:36,190
+مابيعطي positive غير في حالات Rheumatoid arthritis
+
+435
+00:32:36,190 --> 00:32:40,810
+هيك
+
+436
+00:32:40,810 --> 00:32:45,410
+بنكون خلصنا موضوع الـ RFنتمنى من الله أن يجمعنا
+
+437
+00:32:45,410 --> 00:32:49,030
+ونقوم بأداء الجزئية العملي لهذه الموضوع
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/DEW379hmUpQ.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/DEW379hmUpQ.srt
new file mode 100644
index 0000000000000000000000000000000000000000..405f003bace473b56d7af82964a9d5c8d1ee45ff
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/DEW379hmUpQ.srt
@@ -0,0 +1,707 @@
+1
+00:00:01,380 --> 00:00:06,320
+بسم الله الرحمن الرحيم راح ناخد مع بعض موضوع اليوم
+
+2
+00:00:06,320 --> 00:00:11,340
+اللي هو CRP (C-Reactive Protein) برضه من تطبيقات الـ
+
+3
+00:00:11,340 --> 00:00:16,480
+Agglutination Reactions (C-Reactive
+
+4
+00:00:16,480 --> 00:00:21,480
+Protein) إيش هو الـ C-Reactive Protein؟ هو عبارة عن
+
+5
+00:00:21,480 --> 00:00:26,280
+أحد الـ acute phase proteins، يعني أحد أنواع
+
+6
+00:00:26,280 --> 00:00:30,680
+البروتينات اللي بتتكون في الـ serum نتيجة الـ acute
+
+7
+00:00:30,680 --> 00:00:35,060
+Inflammation. طيب، من وين أجى اسمه C-Reactive
+
+8
+00:00:35,060 --> 00:00:41,200
+Protein؟ ووجدوا إنه بيتفاعل مع الـ C-Polysaccharide
+
+9
+00:00:41,200 --> 00:00:45,480
+بتاعة الـ Pneumococci. يعني التسمية ما لهاش علاقة
+
+10
+00:00:45,480 --> 00:00:50,260
+بطبيعة البروتين، لكن لها علاقة بأنه وجدوا أنه بيتفاعل
+
+11
+00:00:50,260 --> 00:00:52,840
+مع الـ C-Polysaccharide بتاعة الـ Pneumococci، بس
+
+12
+00:00:52,840 --> 00:00:56,180
+أما هو الـ C-Reactive Protein عبارة عن acute phase
+
+13
+00:00:56,180 --> 00:00:56,740
+Protein.
+
+14
+00:00:59,330 --> 00:01:03,490
+تمام؟ يُعتبر كـ non-specific inflammatory indicator.
+
+15
+00:01:03,490 --> 00:01:07,210
+إيش يعني non-specific inflammatory indicator؟ يعني
+
+16
+00:01:07,210 --> 00:01:10,170
+في أي مكان في الجسم فيه acute inflammation
+
+17
+00:01:10,170 --> 00:01:15,870
+هيرتفع الـ CRP. تمام؟ هيك معناه يعني
+
+18
+00:01:15,870 --> 00:01:18,830
+مش معناه أنه CRP مرتفع والله عندي اللي هو أكيد
+
+19
+00:01:18,830 --> 00:01:22,830
+inflammation. يعني هو السؤال: عندي أي Inflammation في
+
+20
+00:01:22,830 --> 00:01:26,950
+الجسم هيرفع الـ CRP. بشبه الـ ESR، في شبه بين الاتنين.
+
+21
+00:01:26,950 --> 00:01:31,830
+وهندخلهم في مقارنة. إيش هي خصائص الـ CRP؟ الـ CRP
+
+22
+00:01:31,830 --> 00:01:36,530
+عبارة عن alpha globulin. بيتكون في الكبد (liver).
+
+23
+00:01:36,530 --> 00:01:40,730
+عبارة عن acute phase protein. بيظهر في الـ serum
+
+24
+00:01:40,730 --> 00:01:44,570
+نتيجة الـ inflammation، زي حالات rheumatoid
+
+25
+00:01:44,570 --> 00:01:49,480
+arthritis، الـ lupus مثلًا، and some forms of cancer.
+
+26
+00:01:49,480 --> 00:01:54,700
+بعض أنواع الـ cancer ممكن يرتفع فيها الـ CRP برضه.
+
+27
+00:01:54,700 --> 00:02:00,480
+بيرتفع خلال 4 إلى 6 ساعات بعد الـ infection، بعد
+
+28
+00:02:00,480 --> 00:02:05,080
+الـ surgery، بعد الـ trauma. يعني هو مباشرة بيرتفع
+
+29
+00:02:05,080 --> 00:02:08,680
+بعد حدوث الـ infection أو الضرر اللي صاير في الجسم.
+
+30
+00:02:10,320 --> 00:02:14,320
+برضه الـ CRP elevated due to inflammation in the
+
+31
+00:02:14,320 --> 00:02:18,420
+arteries of the heart. في الـ... لو صار inflammation
+
+32
+00:02:18,420 --> 00:02:21,720
+في الـ arteries بتاعت الـ heart، يُعتبر كـ marker
+
+33
+00:02:21,720 --> 00:02:24,700
+للـ coronary artery disease. يُعتبر في هذه الحالة
+
+34
+00:02:24,700 --> 00:02:29,760
+أو يُسمى في هذه الحالة الـ high-sensitive CRP. ممكن
+
+35
+00:02:29,760 --> 00:02:34,440
+يُعتبر كـ early marker للـ myocardial infarction.
+
+36
+00:02:34,440 --> 00:02:38,700
+CRP
+
+37
+00:02:38,700 --> 00:02:42,460
+is not specific; not specific لأنه في أي
+
+38
+00:02:42,460 --> 00:02:46,500
+inflammation بيرتفع. A high result serves as a general
+
+39
+00:02:46,500 --> 00:02:49,460
+indication of acute inflammation. فيه acute
+
+40
+00:02:49,460 --> 00:02:53,460
+inflammation، but can't show where the inflammation
+
+41
+00:02:53,460 --> 00:02:57,380
+is located or what is causing it.  يعني إيش سبب ال
+
+42
+00:02:57,380 --> 00:03:00,800
+inflammation، أو وين الـ inflammation، ما بقدر أعرف.
+
+43
+00:03:00,800 --> 00:03:03,980
+Other tests are needed to find the cause and
+
+44
+00:03:03,980 --> 00:03:07,660
+location of the inflammation. بحتاج فحوصات أخرى عشان
+
+45
+00:03:07,660 --> 00:03:13,400
+أحدد مكان وموقع الـ inflammation وسببه. يُعتبر كصفات
+
+46
+00:03:13,400 --> 00:03:17,860
+فيزيائية، thermolabile. بيتكسر عند 70 درجة. لو أنا
+
+47
+00:03:17,860 --> 00:03:23,320
+سخنته لـ 70 درجة لمدة 30 دقيقة. شغلة تانية، doesn't
+
+48
+00:03:23,320 --> 00:03:27,820
+cross the human placenta. يعني مش من ضمن الجلوبيولين
+
+49
+00:03:27,820 --> 00:03:33,800
+اللي بتخترق الـ placenta. Acts as an opsonin to help in
+
+50
+00:03:33,800 --> 00:03:37,430
+complement activation and has a receptor on
+
+51
+00:03:37,430 --> 00:03:41,270
+phagocytic cells. إيش يعني؟ يعني هو من ضمن الحاجات
+
+52
+00:03:41,270 --> 00:03:45,270
+اللي بتساعد في الـ immune response. لما بيطلع بيعمل
+
+53
+00:03:45,270 --> 00:03:51,070
+أوبسونين، أوبسونين زي مادة بتجذب الـ complement أو
+
+54
+00:03:51,070 --> 00:03:55,030
+بتساعد في الـ complement activation. وطبعاً هذا
+
+55
+00:03:55,030 --> 00:03:58,950
+الـ receptor على الـ phagocytic cells بيعمل لها
+
+56
+00:03:58,950 --> 00:03:59,470
+activation.
+
+57
+00:04:02,510 --> 00:04:08,530
+نيجي للـ CRP و الـ Coronary Heart Disease. طبعاً
+
+58
+00:04:08,530 --> 00:04:11,050
+أنتوا عارفين الـ Coronary Heart Disease أنه بيصير
+
+59
+00:04:11,050 --> 00:04:14,350
+فيه مشاكل أحياناً في الـ coronary arteries اللي هي
+
+60
+00:04:14,350 --> 00:04:17,110
+الشرايين التاجية اللي بتغذي عضلة القلب. أحياناً
+
+61
+00:04:17,110 --> 00:04:21,810
+بيصير فيها انسداد. وإذا صار فيها انسداد بيصير ذبحة
+
+62
+00:04:21,810 --> 00:04:26,250
+صدرية. يعني إذا سُدّت، أو يعني صار الدم مش قادر يوصل. هاد
+
+63
+00:04:26,250 --> 00:04:29,890
+إيش وظيفتها؟ بتغذي عضلة القلب. يعني بتغذي عضلة القلب
+
+64
+00:04:29,890 --> 00:04:33,650
+نفسها. فإذا صار فيها انسداد أو تلف أو مشكلة أو جلطة
+
+65
+00:04:33,650 --> 00:04:38,990
+الجزء اللي بتغذيه من عضلة القلب هيبدأ يتلف فيما
+
+66
+00:04:38,990 --> 00:04:42,810
+يسمى بـ myocardial infarction. ليش؟ لأنه مش واصلة
+
+67
+00:04:42,810 --> 00:04:46,410
+دم وأكسجين. فبالتالي هيبدأ هذا الجزء يتلف. هذه
+
+68
+00:04:46,410 --> 00:04:49,090
+اللي بتسمى الذبحة الصدرية أو myocardial infarction.
+
+69
+00:04:49,090 --> 00:04:53,550
+طبعاً هذه الذبحة الصدرية، يعني أهم شيء تشخيصها
+
+70
+00:04:53,550 --> 00:04:58,030
+مبكراً. يعني بنفكر، إيش أهم marker بيدل على وجود الـ
+
+71
+00:04:58,030 --> 00:05:00,950
+myocardial infarction؟ من ضمن الحاجات اللي ممكن
+
+72
+00:05:00,950 --> 00:05:03,970
+تساعد في تشخيصها اللي هو الـ high-sensitive CRP.
+
+73
+00:05:03,970 --> 00:05:08,110
+هذا بيبدأ يظهر من within two days of acute
+
+74
+00:05:08,110 --> 00:05:11,890
+myocardial infarction. بيبدأ يرتفع لغاية اليوم
+
+75
+00:05:11,890 --> 00:05:17,290
+الثالث، بيوصل الـ peak بتاعته بعد سبعة أيام. ممكن يصير
+
+76
+00:05:17,290 --> 00:05:23,330
+negative. لكن لو ما صارش negative بعد سبعة أيام، هذا
+
+77
+00:05:23,330 --> 00:05:28,490
+بيدل على أنه صار damage، والـ damage هذا مستمر في
+
+78
+00:05:28,490 --> 00:05:31,990
+الـ cardiac muscle.  ليكشفه. ليش؟ لأن الـ CRP بيظل طالما الـ
+
+79
+00:05:31,990 --> 00:05:36,970
+damage شغال. إذا خلص الـ damage والتلف، يعني هيرجع
+
+80
+00:05:36,970 --> 00:05:40,950
+للطبيعته الـ CRP ويصير negative. لكن طالما المشكلة
+
+81
+00:05:40,950 --> 00:05:45,130
+مستمرة والتلف اللي صار كتير كبير، معنى الكلام إن
+
+82
+00:05:45,130 --> 00:05:50,680
+الـ CRP هيظل مرتفع. من ضمن الـ markers المهمة للـ
+
+83
+00:05:50,680 --> 00:05:55,680
+myocardial infarction، إنزيم اسمه CK-MB (Creatine Kinase
+
+84
+00:05:55,680 --> 00:05:58,760
+Fraction MB). هذا راح تاخذه إن شاء الله في الـ
+
+85
+00:05:58,760 --> 00:06:02,520
+Clinical Chemistry. هذا بيعتبر من الدلائل المبكرة
+
+86
+00:06:02,520 --> 00:06:05,960
+على الـ myocardial infarction. الـ high-sensitive
+
+87
+00:06:05,960 --> 00:06:12,120
+CRP، وجدوا له علاقة وارتفاع متزامن مع الـ CK-MB. يعني
+
+88
+00:06:12,120 --> 00:06:15,600
+بيرتفع معاه بسرعة في أول الـ myocardial infarction.
+
+89
+00:06:15,990 --> 00:06:19,250
+مجرد ما تصير الـ myocardial infarction بيبدأ يرتفع
+
+90
+00:06:19,250 --> 00:06:23,770
+في اليوم الأول أو الثاني. أحياناً الـ CRP إذا كان
+
+91
+00:06:23,770 --> 00:06:30,470
+فيه تلف في عضلة الـ heart ممكن يظل ثلاثة شهور مرتفع. يعني
+
+92
+00:06:30,470 --> 00:06:35,650
+ما بينزلش بعد الـ acute myocardial infarction. طيب،
+
+93
+00:06:35,650 --> 00:06:40,650
+أمتى بنطلب فحص الـ CRP؟ الحالات اللي بينطلب فيها، لو
+
+94
+00:06:40,650 --> 00:06:44,650
+كان فيه suspected inflammation، زي الـ vasculitis،
+
+95
+00:06:45,130 --> 00:06:48,510
+الـ autoimmune disorders، حالات الـ systemic lupus،
+
+96
+00:06:48,510 --> 00:06:52,290
+حالات الـ infection. هي أنا كتير بنطلبه مع الـ ESR
+
+97
+00:06:52,290 --> 00:06:57,750
+لأنه الاتنين بيدلوا على وجود inflammation، لكن
+
+98
+00:06:57,750 --> 00:07:01,050
+الاتنين نفس الشيء، ما بيدلوا لا على مكانه ولا على
+
+99
+00:07:01,050 --> 00:07:05,750
+سبب الـ inflammation. الـ high-sensitive CRP زي ما
+
+100
+00:07:05,750 --> 00:07:10,330
+قلت لكم، هو ممكن يستخدم للمرضى اللي في high risk، يعني
+
+101
+00:07:10,330 --> 00:07:13,450
+يستخدم كـ follow-up لهم. الناس اللي عندهم عرضة
+
+102
+00:07:13,450 --> 00:07:17,710
+لـ coronary heart disease، اللي في high risk، ممكن
+
+103
+00:07:17,710 --> 00:07:22,890
+نستخدمه لهم كـ monitoring باستمرار عشان نمنع، يعني
+
+104
+00:07:22,890 --> 00:07:26,110
+نشوف كيف الدكتور بده يعمل management لحالتهم، كيف
+
+105
+00:07:26,110 --> 00:07:30,950
+يمنعهم أو يحميهم من إنهم يوصلوا لمشكلة
+
+106
+00:07:30,950 --> 00:07:33,510
+الـ myocardial أو لمرحلة الـ myocardial infarction.
+
+107
+00:07:33,510 --> 00:07:37,130
+يعني هو بيستخدم لهم كـ follow-up قبل الـ myocardial
+
+108
+00:07:37,130 --> 00:07:41,350
+infarction، إذا كان عندهم عرضة أو high risk للإصابة
+
+109
+00:07:41,350 --> 00:07:48,330
+بالمشاكل القلبية هذه. طيب، أمتى ممكن ينطلب كمان؟ في بعض
+
+110
+00:07:48,330 --> 00:07:51,910
+الناس اللي عندهم أعراض، زي الـ newborns اللي عندهم
+
+111
+00:07:51,910 --> 00:07:55,550
+أعراض infection، أو ناس عندها sepsis, fever,
+
+112
+00:07:55,870 --> 00:07:58,850
+chills, rapid breathing and heart rate. يعني في
+
+113
+00:07:58,850 --> 00:08:04,080
+علامات للـ inflammation واضحة. ممكن يستخدم كـ follow-
+
+114
+00:08:04,080 --> 00:08:06,900
+up لبعض الحالات زي الـ rheumatoid arthritis،
+
+115
+00:08:06,900 --> 00:08:11,220
+وحالات الـ lupus. أنو أنا الآن عرفت المرض سواء
+
+116
+00:08:11,220 --> 00:08:14,020
+فيه أو مع الـ ESR. أنا عرفت المرض اللي بيؤدي لارتفاع
+
+117
+00:08:14,020 --> 00:08:18,480
+الـ CRP و ESR. الآن بستخدمهم في الـ follow-up.
+
+118
+00:08:18,480 --> 00:08:21,840
+الاتنين، الـ ESR و CRP، أكتر ما بستخدمهم في الـ
+
+119
+00:08:21,840 --> 00:08:26,140
+diagnosis. يعني أنا لقيتهم عالين، تمام، وعرفت المرض.
+
+120
+00:08:26,620 --> 00:08:29,740
+الآن من باب المتابعة، ممكن أستخدمهم بس في الـ
+
+121
+00:08:29,740 --> 00:08:32,160
+follow-up، في البداية ما بيقدروش يقولوا لي أي شيء
+
+122
+00:08:32,160 --> 00:08:39,800
+عن المشكلة. طيب،
+
+123
+00:08:39,800 --> 00:08:44,960
+هنا في هدف ثاني لاستخدام الـ CRP. هلقيت في حالات
+
+124
+00:08:44,960 --> 00:08:50,140
+العمليات الجراحية، بقول لك الـ CRP بيرتفع من 4 إلى 6
+
+125
+00:08:50,140 --> 00:08:56,250
+ساعات بعد العملية. يعني بيرتفع ارتفاع سريع. بعد هيك
+
+126
+00:08:56,250 --> 00:09:01,950
+بيبلش ينزل في اليوم الثالث، بتلاقي تقريباً نزل. يعني
+
+127
+00:09:01,950 --> 00:09:07,230
+طيب، بقول لك إنه إذا الـ CRP استمر في الارتفاع بعد
+
+128
+00:09:07,230 --> 00:09:11,590
+ثلاثة أيام، معنى الكلام إن الجروح التهبت، إنه فيه مشكلة
+
+129
+00:09:11,590 --> 00:09:14,310
+أو فيه infection في جروح العملية. يعني هو الوضع
+
+130
+00:09:14,310 --> 00:09:17,630
+الطبيعي بعد ثلاثة أيام يبدأ يرجع لطبيعته، لكن إذا
+
+131
+00:09:17,630 --> 00:09:21,490
+استمر في الارتفاع بعد ثلاثة أيام، معنى الكلام إن
+
+132
+00:09:21,490 --> 00:09:25,130
+الجروح فيه التهاب (inflammation) أو infection. مع
+
+133
+00:09:25,130 --> 00:09:28,190
+هذا، بيصير الدكتور بينتبه إن هذا الجروح بده
+
+134
+00:09:28,190 --> 00:09:36,470
+متابعة. هنا برضه هذه النقطة نوهنا لها، إنه بنشوف
+
+135
+00:09:36,470 --> 00:09:40,010
+إذا إحنا أعطينا الـ patient علاج معين من باب
+
+136
+00:09:40,010 --> 00:09:43,510
+المتابعة. إذا أعطينا مثلاً treatment للـ cancer أو
+
+137
+00:09:43,510 --> 00:09:46,230
+للـ infection، ممكن نعمل الـ CRP من باب الـ follow-
+
+138
+00:09:46,230 --> 00:09:50,790
+up، أو نشوف هل العلاج الشخص هذا استجاب عليه كويس
+
+139
+00:09:50,790 --> 00:09:55,340
+ولا لأ. CRP levels rise rapidly with infection, but
+
+140
+00:09:55,340 --> 00:09:58,200
+quickly become normal if the patient is responding to
+
+141
+00:09:58,200 --> 00:10:02,220
+treatment. CRP بيرتفع بسرعة، لكن إذا الإنسان هذا
+
+142
+00:10:02,220 --> 00:10:06,700
+استجاب للعلاج بشكل جيد، هتلاقي إن الـ CRP بلش يرجع
+
+143
+00:10:06,700 --> 00:10:12,180
+لطبيعته. هنا
+
+144
+00:10:12,180 --> 00:10:16,080
+في عندي مقارنة بين الـ CRP و الـ ESR. كون الاتنين
+
+145
+00:10:16,080 --> 00:10:20,280
+بيرتفعوا في الـ inflammation، والاتنين بيدلوا على non-
+
+146
+00:10:20,280 --> 00:10:25,360
+specific inflammation. الـ CRP يُعتبر more sensitive
+
+147
+00:10:25,360 --> 00:10:29,520
+and a more accurate reflection of the acute phase response
+
+148
+00:10:29,520 --> 00:10:36,040
+than ESR. إيش يعني؟ يعني الـ CRP هتلاقيه بيرتفع قبل
+
+149
+00:10:36,040 --> 00:10:40,160
+الـ ESR، بيدل على الـ acute inflammation في المراحل
+
+150
+00:10:40,160 --> 00:10:48,610
+الأولى لها. لكن الـ ESR بيظل فترات أطول مرتفع بعد
+
+151
+00:10:48,610 --> 00:10:51,890
+ما تخلص الـ inflammation، أو يعني في مراحل متقدمة
+
+152
+00:10:51,890 --> 00:10:55,430
+من الـ inflammation، ممكن ألاقي الـ ESR مرتفع بينما
+
+153
+00:10:55,430 --> 00:11:00,390
+الـ CRP نزل. ثاني نقول: CRP is a more sensitive and
+
+154
+00:11:00,390 --> 00:11:03,550
+accurate reflection of the acute phase response
+
+155
+00:11:03,550 --> 00:11:06,730
+يعني بيدل أكثر أو بيرتفع أكثر في الـ acute phase
+
+156
+00:11:06,730 --> 00:11:12,750
+أكثر من الـ ESR. Since ESR may be may be normal while
+
+157
+00:11:12,750 --> 00:11:17,090
+CRP is elevated. يعني ممكن الـ ESR تكون normal لسه
+
+158
+00:11:17,090 --> 00:11:21,670
+لكن الـ CRP ارتفع. But CRP appears and disappears
+
+159
+00:11:21,670 --> 00:11:26,090
+more quickly. بيطلع وبينزل وبيختفي بسرعة أسرع من
+
+160
+00:11:26,090 --> 00:11:32,890
+الـ ESR. لكن الـ ESR ممكن تظل elevated لفترة أطول
+
+161
+00:11:32,890 --> 00:11:38,620
+(longer period) من CRP. إذا، إيش الفرق بينهم؟ هذا في الـ acute
+
+162
+00:11:38,620 --> 00:11:42,120
+infection، بيرتفع اللي هو الـ CRP، بيرتفع وبينزل بسرعة
+
+163
+00:11:42,120 --> 00:11:45,400
+في الـ acute phase of inflammation. الـ CRP بياخد
+
+164
+00:11:45,400 --> 00:11:50,280
+وقت أطول لما يبدأ يرتفع، وبينزل بعد فترة طويلة. يعني
+
+165
+00:11:50,280 --> 00:11:53,600
+ما بيرتفعش وبينزل بسرعة، لأ، بيطول لغاية ما يرجع
+
+166
+00:11:53,600 --> 00:11:54,400
+للطبيعة.
+
+167
+00:12:05,720 --> 00:12:12,460
+عندي هنا مقارنة، أو في حالات ممكن تزيد فيها الـ ESR
+
+168
+00:12:12,460 --> 00:12:16,460
+والـ CRP تكون normal. زي الـ pregnancy، الـ
+
+169
+00:12:16,460 --> 00:12:18,960
+pregnancy بيزيد الـ fibrinogen، الـ fibrinogen
+
+170
+00:12:18,960 --> 00:12:22,720
+بيزيد الـ ESR بس ما بيزيد الـ CRP، أو ما بيكون فيه
+
+171
+00:12:22,720 --> 00:12:27,400
+CRP positive. نفروز الكلى (nephrosis)، لأنه بيصير فيه
+
+172
+00:12:27,400 --> 00:12:31,380
+hypoalbuminemia، والـ fibrinogen والـ globulin
+
+173
+00:12:31,380 --> 00:12:35,420
+بيزيدوا. فبالتالي برضه بيزيدوا الـ ESR. حالة الأنميا (anemia)
+
+174
+00:12:35,420 --> 00:12:39,040
+لأن الـ packed cells بتكون قليلة، فبتزيد نسبة
+
+175
+00:12:39,040 --> 00:12:43,420
+البلازما. الـ ESR هتكون فيها عالية، والـ CRP ما
+
+176
+00:12:43,420 --> 00:12:48,340
+بتتأثر. بعض الـ drugs زي الـ steroids بتأثر على الـ
+
+177
+00:12:48,340 --> 00:12:54,100
+ESR بس ما بتأثر على الـ CRP.
\ No newline at end of file
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/DEW379hmUpQ_raw.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/DEW379hmUpQ_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..ca2d9c730ad17c498eaf53b53da910891f63c4ba
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/DEW379hmUpQ_raw.srt
@@ -0,0 +1,800 @@
+1
+00:00:01,380 --> 00:00:06,320
+بسم الله الرحمن الرحيم راح ناخد مع بعض موضوع اليوم
+
+2
+00:00:06,320 --> 00:00:11,340
+اللي هو CRP CReactive Protein برضه من تطبيقات الـ
+
+3
+00:00:11,340 --> 00:00:16,480
+Agglutination Reactions CReactive
+
+4
+00:00:16,480 --> 00:00:21,480
+Protein إيش هو الـ CReactive Protein؟ هو عبارة عن
+
+5
+00:00:21,480 --> 00:00:26,280
+أحد الـ acute phase proteins يعني أحد أنواع
+
+6
+00:00:26,280 --> 00:00:30,680
+البروتيناتاللي بتتكون في الـ Serum نتيجة الـ Acute
+
+7
+00:00:30,680 --> 00:00:35,060
+Inflammation طيب، من وين أجى اسمه C-Reactive
+
+8
+00:00:35,060 --> 00:00:41,200
+Protein ووجدوا إنه بتفاعل مع الـ C-Polysaccharide
+
+9
+00:00:41,200 --> 00:00:45,480
+بتاعة الـ Neumococci يعني التسمية ما لهاش علاقة
+
+10
+00:00:45,480 --> 00:00:50,260
+بطبيعة البروتين لكن لها علاقة إنه وجدوا هو بتفاعل
+
+11
+00:00:50,260 --> 00:00:52,840
+مع الـ C-Polysaccharide بتاعة الـ Neumococci، بس
+
+12
+00:00:52,840 --> 00:00:56,180
+أما هو الـ C-Reactive Protein عبارة عن Acute Phase
+
+13
+00:00:56,180 --> 00:00:56,740
+Protein
+
+14
+00:00:59,330 --> 00:01:03,490
+تمام؟ يُعتبر كـNon-specific inflammatory indicator
+
+15
+00:01:03,490 --> 00:01:07,210
+إيش يعني Non-specific inflammatory indicator؟ يعني
+
+16
+00:01:07,210 --> 00:01:10,170
+Anywhere في الجسم فيه inflammation أكيوت
+
+17
+00:01:10,170 --> 00:01:15,870
+inflammation هيرتفع الـ CRP تمام؟ هيك معناه يعني
+
+18
+00:01:15,870 --> 00:01:18,830
+مش معناه أنه CRP مرتفع والله عندي اللي هو أكيد
+
+19
+00:01:18,830 --> 00:01:22,830
+لازم هو يعني هو السؤالهيعندي أي Inflammation في
+
+20
+00:01:22,830 --> 00:01:26,950
+الجسم هيرفع الـ CRP بشبه الـ ESR في شبه بين اتنين
+
+21
+00:01:26,950 --> 00:01:31,830
+و هندخلهم في مقارنة إيش هي خصائص الـ CRP الـ CRP
+
+22
+00:01:31,830 --> 00:01:36,530
+عبارة عن Globulin Alpha Globulin بيتكون في الليفر
+
+23
+00:01:36,530 --> 00:01:40,730
+عبارة عن acute phase protein بيظهر بالـ Serum
+
+24
+00:01:40,730 --> 00:01:44,570
+نتيجة الـ Inflammation زي حالات Rheumatoid
+
+25
+00:01:44,570 --> 00:01:49,480
+Arthritisالـ Lobus مثلًا، and some forms of cancer
+
+26
+00:01:49,480 --> 00:01:54,700
+بعض أنواع الـ cancer ممكن يرتفع فيها الـ CRP برضه
+
+27
+00:01:54,700 --> 00:02:00,480
+بيرتفع خلال 4 إلى 6 ساعات بعد الـ infection بعد
+
+28
+00:02:00,480 --> 00:02:05,080
+الـ surgery، بعد الـ trauma يعني هو مباشرة بيرتفع
+
+29
+00:02:05,080 --> 00:02:08,680
+بعد حدوث الـ infection أو الدرر اللي صاير في الجسم
+
+30
+00:02:10,320 --> 00:02:14,320
+برضه الـ CRP elevated due to inflammation in the
+
+31
+00:02:14,320 --> 00:02:18,420
+arteries of the heart في ال .. لو صار inflammation
+
+32
+00:02:18,420 --> 00:02:21,720
+في الـ arteries بتاعت الـ heart يُعتبر كـ marker
+
+33
+00:02:21,720 --> 00:02:24,700
+للـ coronary artery disease يُعتبر في هذه الحالة
+
+34
+00:02:24,700 --> 00:02:29,760
+أو يُسمى في هذه الحالة الـ high sensitive CRP ممكن
+
+35
+00:02:29,760 --> 00:02:34,440
+يُعتبر كـ early marker للـ myocardial infarction
+
+36
+00:02:34,440 --> 00:02:38,700
+CRP
+
+37
+00:02:38,700 --> 00:02:42,460
+is not specificnot specific لأنه في أي
+
+38
+00:02:42,460 --> 00:02:46,500
+inflammation بيرتفع a high result serve as general
+
+39
+00:02:46,500 --> 00:02:49,460
+indication of acute inflammation بيه acute
+
+40
+00:02:49,460 --> 00:02:53,460
+inflammation but can't show where the inflammation
+
+41
+00:02:53,460 --> 00:02:57,380
+is located or what causing it so يعني إيش سبب ال
+
+42
+00:02:57,380 --> 00:03:00,800
+inflammation أو when ال inflammation ما بقدر أعرف
+
+43
+00:03:00,800 --> 00:03:03,980
+other tests are needed to find the cause and
+
+44
+00:03:03,980 --> 00:03:07,660
+location of inflammation بحتاج فحوصات أخرى عشان
+
+45
+00:03:07,660 --> 00:03:13,400
+أحدد مكان وموقع ال inflammation وسببهيعتبر كصفات
+
+46
+00:03:13,400 --> 00:03:17,860
+فيزيائية Thermolabile بيتكسر عند 70 درجة لو أنا
+
+47
+00:03:17,860 --> 00:03:23,320
+دفعت لـ 70 درجة لـ 30 دقيقة شغلة تانية، don't
+
+48
+00:03:23,320 --> 00:03:27,820
+cross human placenta يعني مش من ضمن الجلوبيولين
+
+49
+00:03:27,820 --> 00:03:33,800
+اللي بتخترق الـ placenta Act as opsonin to help in
+
+50
+00:03:33,800 --> 00:03:37,430
+complement activationand has a receptor on
+
+51
+00:03:37,430 --> 00:03:41,270
+phagocytic cells إيش يعني؟ يعني هو من ضمن الحاجات
+
+52
+00:03:41,270 --> 00:03:45,270
+اللي بتساعد في الـimmune response لما بيطلع بيعمل
+
+53
+00:03:45,270 --> 00:03:51,070
+أبسنين، أبسنين زي مادة بتجذب الـComplement أو
+
+54
+00:03:51,070 --> 00:03:55,030
+بتساعد في الـComplement activation وطبعاً هذا
+
+55
+00:03:55,030 --> 00:03:58,950
+الـReceptor على الـphagocytic cells بيعمللها
+
+56
+00:03:58,950 --> 00:03:59,470
+activation
+
+57
+00:04:02,510 --> 00:04:08,530
+نيجي للـ CRP و الـ Coronary Heart Disease طبعاً
+
+58
+00:04:08,530 --> 00:04:11,050
+أنتوا عارفين الـ Coronary Heart Disease أنه بيصير
+
+59
+00:04:11,050 --> 00:04:14,350
+مشاكل أحياناً في الـ coronary arteries اللي هي
+
+60
+00:04:14,350 --> 00:04:17,110
+الشراينة التاجية اللي بتغذي عضلة القلب أحياناً
+
+61
+00:04:17,110 --> 00:04:21,810
+بيصير فيها تسلب وإذا صار فيها تسلب بيصير ذبحة
+
+62
+00:04:21,810 --> 00:04:26,250
+صدرية يعني إذا سكت أو يعني صارت دم مش قادر هي هادة
+
+63
+00:04:26,250 --> 00:04:29,890
+إيش وظيفتها؟ بتغذي عضلة القلبيعني بتغذي عضلة القلب
+
+64
+00:04:29,890 --> 00:04:33,650
+نفسها فإذا صار فيها تسديد أو تلف أو مشكلة أو جلطة
+
+65
+00:04:33,650 --> 00:04:38,990
+الجزء اللي بتغذيه من عضلة القلب هيبدأ يتلف فيما
+
+66
+00:04:38,990 --> 00:04:42,810
+يسمى بالـ Myocardial Infarction ليش؟ لأنه مش واصله
+
+67
+00:04:42,810 --> 00:04:46,410
+دم و أكسوجين فبالتالي هيبدأ هذا الجزء يتفر هذه
+
+68
+00:04:46,410 --> 00:04:49,090
+اللي بتسمى الذبحة الصدرية أو Myocardial Infarction
+
+69
+00:04:49,090 --> 00:04:53,550
+طبعاً هذه الذبحة الصدرية يعني أهم شيء تشخيصها
+
+70
+00:04:53,550 --> 00:04:58,030
+مبكرايعني بتفننوا إيش أهم marker بيدل على وجود الـ
+
+71
+00:04:58,030 --> 00:05:00,950
+Myocardial Infarction من ضمن الحاجات اللي ممكن
+
+72
+00:05:00,950 --> 00:05:03,970
+تساعد في تشخيصها اللي هو الـ High Sensitive CRP
+
+73
+00:05:03,970 --> 00:05:08,110
+هذا بيبدأ يظهر من when to do days of acute
+
+74
+00:05:08,110 --> 00:05:11,890
+myocardial infarction بيبدأ يرتفع لغاية اليوم
+
+75
+00:05:11,890 --> 00:05:17,290
+التالت بوصل الـ peak بتاعته بعد سبع أيام ممكن يصير
+
+76
+00:05:17,290 --> 00:05:23,330
+negative لكن لو ماصارش negative بعد سبع أيامفهذا
+
+77
+00:05:23,330 --> 00:05:28,490
+بيدل على إنه صار Damage والـ Damage هذا مستمر في
+
+78
+00:05:28,490 --> 00:05:31,990
+الـ Card يكشفه ليش؟ لأن الـ CRP بيظل طالما الـ
+
+79
+00:05:31,990 --> 00:05:36,970
+Damage شغال إذا خلص الـ Damage والتلف يعني هيرجع
+
+80
+00:05:36,970 --> 00:05:40,950
+للطبيعته الـ CRP ويصير Negative لكن طالما المشكلة
+
+81
+00:05:40,950 --> 00:05:45,130
+مستمرة والتلف اللي صار كتير كبير معنى الكلام إن
+
+82
+00:05:45,130 --> 00:05:50,680
+الـ CRP هيظل مرتفع من ضمن الـ Marketers المهمةللـ
+
+83
+00:05:50,680 --> 00:05:55,680
+Myocardial Infarction إنزايم اسمه CK-Kinase
+
+84
+00:05:55,680 --> 00:05:58,760
+Fraction MB هذا راح تاخده ان شاء الله في الـ
+
+85
+00:05:58,760 --> 00:06:02,520
+Clinical Chemistry هذا بيعتبر من الدلائل المبكرة
+
+86
+00:06:02,520 --> 00:06:05,960
+على الـ Myocardial Infarction الـ High Sensitive
+
+87
+00:06:05,960 --> 00:06:12,120
+CRB وجده إله علاقة وارتفاع متزامن مع الـ CKMB يعني
+
+88
+00:06:12,120 --> 00:06:15,600
+بيرتفع معاه بسرعة في أول الـ Myocardial Infarction
+
+89
+00:06:15,990 --> 00:06:19,250
+مجرد ما تصير الـ myocardial infarction بيبدأ يرتفع
+
+90
+00:06:19,250 --> 00:06:23,770
+في اليوم الأول أو التاني أحياناً الـ CRP إذا كان
+
+91
+00:06:23,770 --> 00:06:30,470
+فيه عضلة الـ heart ممكن يظل تلت شهور مرتفع يعني
+
+92
+00:06:30,470 --> 00:06:35,650
+ماينزلش بعد الـ acute myocardial infarction طيب
+
+93
+00:06:35,650 --> 00:06:40,650
+أمتى بنطلب فحص الـ CRP الحالات اللي بينطلب فيها لو
+
+94
+00:06:40,650 --> 00:06:44,650
+كان فيه suspected inflammation زي الـ vasculitis
+
+95
+00:06:45,130 --> 00:06:48,510
+الـ Autoimmune Disorder حالات الـ Systemic Lobes
+
+96
+00:06:48,510 --> 00:06:52,290
+حالات الـ Infection هي انا كتير بنطلب مع الـ ESR
+
+97
+00:06:52,290 --> 00:06:57,750
+لأنه التنين بدلوا على وجود Inflammation لكن
+
+98
+00:06:57,750 --> 00:07:01,050
+الاتنين نفس الاشي ما بدلوا لا على مكانه ولا على
+
+99
+00:07:01,050 --> 00:07:05,750
+سبب الـ Inflammation الـ High Sensitive CRP زي ما
+
+100
+00:07:05,750 --> 00:07:10,330
+قلتلكم هو ممكن يستخدم للمرضى اللي في high riskيعني
+
+101
+00:07:10,330 --> 00:07:13,450
+يستخدم كـFollow-up لهم الناس اللي عندهم عرضة
+
+102
+00:07:13,450 --> 00:07:17,710
+لـCoronary Heart Disease اللي في High Risk ممكن
+
+103
+00:07:17,710 --> 00:07:22,890
+نستخدمه لهم كـMonitoring باستمرار عشان نمنع يعني
+
+104
+00:07:22,890 --> 00:07:26,110
+نشوف كيف الدكتور بدي يعمل Management لحالتهم كيف
+
+105
+00:07:26,110 --> 00:07:30,950
+يمنعهم أو يحميهم من إنهم يوصلوا لمشكلة
+
+106
+00:07:30,950 --> 00:07:33,510
+الـMyocardium أو لمرحلة الـMyocardial Infarction
+
+107
+00:07:33,510 --> 00:07:37,130
+يعني هو بيستخدم لهم كـFollow-up قبل الـMyocardial
+
+108
+00:07:37,130 --> 00:07:41,350
+Infarction إذا كان عندهم عرضةأو high risk للإصابة
+
+109
+00:07:41,350 --> 00:07:48,330
+بالمشاكل القلب هذه طيب أمتى ممكن ينطلب كمان في بعض
+
+110
+00:07:48,330 --> 00:07:51,910
+الناس اللي عندهم أعراض زي الـ newborn اللي عندهم
+
+111
+00:07:51,910 --> 00:07:55,550
+أعراض ال infection أو ناس عندها sepsis, fever,
+
+112
+00:07:55,870 --> 00:07:58,850
+chills, rapid breathing and heart rate يعني في
+
+113
+00:07:58,850 --> 00:08:04,080
+علامات لل inflammation واضحةممكن يستخدم كـ Follow
+
+114
+00:08:04,080 --> 00:08:06,900
+-up لبعض الحالات زي الـ Rheumatoid Arthritis
+
+115
+00:08:06,900 --> 00:08:11,220
+وحالات الـ Lubus أن هو أنا الآن عرفت المرض سواء
+
+116
+00:08:11,220 --> 00:08:14,020
+فيه أو الـ ESR أنا عرفت المرض اللي يؤدى لارتفاع
+
+117
+00:08:14,020 --> 00:08:18,480
+الـ CRP و ESR الآن بستخدمهم في الـ Follow-up
+
+118
+00:08:18,480 --> 00:08:21,840
+التنين الـ ESR و CRP أكتر ما بستخدمهم في الـ
+
+119
+00:08:21,840 --> 00:08:26,140
+Diagnosis يعني أنا لاقيتهم عالين تمام وعرفت المرض
+
+120
+00:08:26,620 --> 00:08:29,740
+الآن من باب المتابعة ممكن أستخدمهم بس في الـ
+
+121
+00:08:29,740 --> 00:08:32,160
+«diagnosis» في البداية ما بيقدروش يقولوا لي أشي
+
+122
+00:08:32,160 --> 00:08:39,800
+المشكلة طيب،
+
+123
+00:08:39,800 --> 00:08:44,960
+هنا في هدف تاني لاستخدام الـ CRP هلقيت في حالات
+
+124
+00:08:44,960 --> 00:08:50,140
+العمليات الجراحية بقولك الـ CRP برتفع من 4 إلى 6
+
+125
+00:08:50,140 --> 00:08:56,250
+ساعات بعد العملية يعني برتفع ارتفاع سريعبعد هيك
+
+126
+00:08:56,250 --> 00:09:01,950
+بيبلش ينزل في اليوم التالت بتلاقي تقريبا نزل يعني
+
+127
+00:09:01,950 --> 00:09:07,230
+طيب بقولك إنه إذا الـ CRP استمر في الارتفاع بعد
+
+128
+00:09:07,230 --> 00:09:11,590
+تلت أيام معنى الكلام إن الجروح التهب إنه فيه مشكلة
+
+129
+00:09:11,590 --> 00:09:14,310
+أو فيه infection في جروح العملية يعني هو الوضع
+
+130
+00:09:14,310 --> 00:09:17,630
+الطبيعي بعد تلت أيام يبدأ يرجع لطبيعته لكن إذا
+
+131
+00:09:17,630 --> 00:09:21,490
+استمر في الارتفاع بعد تلت أيام معنى الكلام إن
+
+132
+00:09:21,490 --> 00:09:25,130
+الجروح فيه التهب أو inflammation أو infectionمع
+
+133
+00:09:25,130 --> 00:09:28,190
+أنها بيصير الدكتور بينتبه إنه هذا الجروح بده
+
+134
+00:09:28,190 --> 00:09:36,470
+متابعة هنا برضه هذه النقطة نوّهنا إلها إنه بنشوف
+
+135
+00:09:36,470 --> 00:09:40,010
+إذا إحنا أعطينا ال patient علاج معين من باب
+
+136
+00:09:40,010 --> 00:09:43,510
+المتابعة إذا أعطينا مثلا treatment للـ Cancer أو
+
+137
+00:09:43,510 --> 00:09:46,230
+للـ Infection ممكن نعمل الـ CRP من باب ال follow
+
+138
+00:09:46,230 --> 00:09:50,790
+-up أو نشوف هل العلاج الشخص هذا استجاب عليه كويس
+
+139
+00:09:50,790 --> 00:09:55,340
+ولا لأCRP level rise rapidly with infection but
+
+140
+00:09:55,340 --> 00:09:58,200
+quickly become normal if you are responding to
+
+141
+00:09:58,200 --> 00:10:02,220
+treatment CRP برتفع بسرعة لكن إذا البني آدم هذا
+
+142
+00:10:02,220 --> 00:10:06,700
+استجاب للعلاج بشكل جيد هتلاقي إن الـ CRP بلش يرجع
+
+143
+00:10:06,700 --> 00:10:12,180
+لطبيعته هنا
+
+144
+00:10:12,180 --> 00:10:16,080
+في عندي مقارنة بين الـ CRP و الـ ASR كون التنين
+
+145
+00:10:16,080 --> 00:10:20,280
+برتفعوا في ال inflammation والتنين بدله على non
+
+146
+00:10:20,280 --> 00:10:25,360
+specific inflammationالـ CRP يعتبر more sensitive
+
+147
+00:10:25,360 --> 00:10:29,520
+and accurate reflection of acute phase response
+
+148
+00:10:29,520 --> 00:10:36,040
+than ESR إيش يعني؟ يعني الـ CRP هتلاقيه بيرتفع قبل
+
+149
+00:10:36,040 --> 00:10:40,160
+الـ ESR بيدل على الـ acute inflammation في المراحل
+
+150
+00:10:40,160 --> 00:10:48,610
+الأولى لإلها لكن الـ ESRبيظل فترات أطول مرتفع بعد
+
+151
+00:10:48,610 --> 00:10:51,890
+ما تخلص الـ Inflammation أو يعني في مراحل متقدمة
+
+152
+00:10:51,890 --> 00:10:55,430
+من الـ Inflammation ممكن ألاقي الـ ESR مرتفع بينما
+
+153
+00:10:55,430 --> 00:11:00,390
+الـ CRB نزل تاني نقول CRB is more sensitive and
+
+154
+00:11:00,390 --> 00:11:03,550
+accurate reflection of the acute phase response
+
+155
+00:11:03,550 --> 00:11:06,730
+يعني بيدل أكتر أو بيرتفع أكتر في الـ acute phase
+
+156
+00:11:06,730 --> 00:11:12,750
+أكتر من الـ ESR since ESR may bemay be normal why
+
+157
+00:11:12,750 --> 00:11:17,090
+CRP is elevated يعني ممكن الـ ESR تكون normal لسه
+
+158
+00:11:17,090 --> 00:11:21,670
+لكن الـ CRP ارتفع but CRP appear and disappear
+
+159
+00:11:21,670 --> 00:11:26,090
+more quickly بطلع و بنزل و بيختفي بسرعة أسرع من
+
+160
+00:11:26,090 --> 00:11:32,890
+الـ ESR لكن الـ ESR ممكن تظل elevated لـ longer
+
+161
+00:11:32,890 --> 00:11:38,620
+period than CRPإذا إيش الفرق بينهم؟ هذا بالـ Acute
+
+162
+00:11:38,620 --> 00:11:42,120
+Infection برتفع اللي هو الـ CRP برتفع و بنزل بسرعة
+
+163
+00:11:42,120 --> 00:11:45,400
+في الـ Acute Phase of Inflammation الـ CRP بياخد
+
+164
+00:11:45,400 --> 00:11:50,280
+وقت أطول لما يبدأ يرتفع وبنقيق بعد فترة طويلة يعني
+
+165
+00:11:50,280 --> 00:11:53,600
+ما برتفعش و بنزل بسرعة لأ بطول لغاية ما يرجع
+
+166
+00:11:53,600 --> 00:11:54,400
+لطبيعة
+
+167
+00:12:05,720 --> 00:12:12,460
+عندي هنا مقارنة أو في حالات ممكن تزيد فيها الـ ESR
+
+168
+00:12:12,460 --> 00:12:16,460
+والـ CRB تكون Normal زي الـ Pregnancy الـ
+
+169
+00:12:16,460 --> 00:12:18,960
+Pregnancy بيزيد الـ Fibrinogen الـ Fibrinogen
+
+170
+00:12:18,960 --> 00:12:22,720
+بيزود الـ ESR بس ما بيزود الـ CRB أو ما بيكون فيه
+
+171
+00:12:22,720 --> 00:12:27,400
+CRB positive نفروزز نفروزز لأنه بيصير فيه
+
+172
+00:12:27,400 --> 00:12:31,380
+Hypoalbuminemia والـ Fibrinogen والـ Globulin
+
+173
+00:12:31,380 --> 00:12:35,420
+بيزيدوا فبالتالي برضه بيزودوا الـ ESRحالة الأنميا
+
+174
+00:12:35,420 --> 00:12:39,040
+لأن الـ Bagged cells بتكون قليلة فبتزيد نسبة
+
+175
+00:12:39,040 --> 00:12:43,420
+البلازما الـ ESR هتكون فيها عالية والـ CRP ما
+
+176
+00:12:43,420 --> 00:12:48,340
+بتتأثر بعض ال drugs زي الـ Steroids بتأثر على الـ
+
+177
+00:12:48,340 --> 00:12:54,100
+ESR بس ما بتأثر على الـ CRP الـ Normal Value من 0
+
+178
+00:12:54,100 --> 00:13:01,940
+.02 إلى 1.32 ميلي جرام بديسلتر طريقة الشغل نفس
+
+179
+00:13:01,940 --> 00:13:08,130
+الطريقة اللي حكينا عنهابالـ بالـ RF بالظبط drop من
+
+180
+00:13:08,130 --> 00:13:11,950
+الـ reagent مع خمسين micron أو drop من ال sample
+
+181
+00:13:11,950 --> 00:13:15,370
+إذا positive أو negative بنعمل serial dilution
+
+182
+00:13:15,370 --> 00:13:20,030
+positive عشان نحدد ال title negative عشان خوف ما
+
+183
+00:13:20,030 --> 00:13:24,230
+يكون في عندنا برزان فينوملةالـ Titer ممكن نكتب
+
+184
+00:13:24,230 --> 00:13:28,010
+Titer النتيجة أو نكتبها بالـ milligram per
+
+185
+00:13:28,010 --> 00:13:32,250
+deciliter هنا بقولك بعد ما نخلص الـ Titer بنضربه
+
+186
+00:13:32,250 --> 00:13:36,750
+بـ 6 milligram per deciliter أو 0.6 milligram per
+
+187
+00:13:36,750 --> 00:13:39,870
+deciliter عشان تطلع عندي النتيجة بالـ milligram
+
+188
+00:13:39,870 --> 00:13:43,170
+per deciliter يعني في عندي برضه طريقتين للتعبير عن
+
+189
+00:13:43,170 --> 00:13:47,570
+النتيجة إما milligram per deciliter أو أني أكتب
+
+190
+00:13:47,570 --> 00:13:52,650
+Titer مباشرةهذه طريقة الـ dilution للـ cereal
+
+191
+00:13:52,650 --> 00:13:56,330
+dilution أنه أنا بحضر قنابيب 50 مايكرون من الـ
+
+192
+00:13:56,330 --> 00:14:00,430
+sample مع 50 من الـ normal saline بصير أخد كل
+
+193
+00:14:00,430 --> 00:14:03,390
+واحدة من الأنبوبة اللي قبلها بيكون عندي الـ titer
+
+194
+00:14:03,390 --> 00:14:06,690
+في الأنبوبة هذه 1 إلى 2 من الـ sample المباشرة
+
+195
+00:14:06,690 --> 00:14:10,850
+بيكون الـ titer 1 ل 1 الأنبوبة التانية 2، التالتة
+
+196
+00:14:10,850 --> 00:14:15,650
+4، التمانية وبعد هيك باخد من الـ dilution هذا 50
+
+197
+00:14:15,650 --> 00:14:20,840
+وبشتغل عليهالـ CRB وبشوف إيش آخر tube أعطتني
+
+198
+00:14:20,840 --> 00:14:24,480
+positive بيكون هو الـ titer بتاع الفحص اللي عندي
+
+199
+00:14:24,480 --> 00:14:29,120
+أو بتاع العينة اللي عندي عافية هيك بنكون خلصنا
+
+200
+00:14:29,120 --> 00:14:32,660
+الفحص التاني على ال agglutination اللي هو CRB
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/Qdpgq8sG-To.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/Qdpgq8sG-To.srt
new file mode 100644
index 0000000000000000000000000000000000000000..81811dc5d0353e804571b45ec2321754162f9eb6
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/Qdpgq8sG-To.srt
@@ -0,0 +1,1562 @@
+1
+00:00:00,770 --> 00:00:04,370
+بسم الله الرحمن الرحيم اليوم إن شاء الله رب
+
+2
+00:00:04,370 --> 00:00:08,330
+العالمين راح يكون موضوعنا الـ Viral Hepatitis راح
+
+3
+00:00:08,330 --> 00:00:11,430
+ناخد الـ Serology of Viral Hepatitis والـ
+
+4
+00:00:11,430 --> 00:00:15,990
+Hepatitis Markers وكيف بيتم تقييم الحالة ومعرفة
+
+5
+00:00:15,990 --> 00:00:18,250
+الـ Stage بتاعة المرض إذا كان موجود إحنا عارفين
+
+6
+00:00:18,250 --> 00:00:24,530
+الـ Viral Hepatitis بيسببه فيروس بينتمي إلى أحد
+
+7
+00:00:24,530 --> 00:00:28,490
+هذه الفيروسات أكثر ثلاث أنواع شيوعاً اللي هو الـ
+
+8
+00:00:28,490 --> 00:00:33,240
+Hepatitis A Virus والـ B فيروس والـ C فيروس لأن
+
+9
+00:00:33,240 --> 00:00:36,220
+نوعين الآخرين مش كتير شائعين اللي هما الـ
+
+10
+00:00:36,220 --> 00:00:41,480
+Hepatitis D والـ Hepatitis E فيروس الـ Hepatitis A
+
+11
+00:00:41,480 --> 00:00:47,000
+فيروس عبارة عن RNA فيروس هما كلهم RNA فيروسات مع  ده
+
+12
+00:00:47,000 --> 00:00:52,360
+Hepatitis B عبارة عن DNA فيروس. كلهم RNA فيروسات مع
+
+13
+00:00:52,360 --> 00:00:54,800
+ده Hepatitis B. يعني الآن ليش إحنا بنعمل فحص الـ
+
+14
+00:00:54,800 --> 00:01:00,830
+Hepatitis؟ في مجموعة أسباب، السبب الأول: إذا كان الشخص
+
+15
+00:01:00,830 --> 00:01:05,030
+مصاب بـ Viral Hepatitis، بدي أعرف إيش نوعه A أو B
+
+16
+00:01:05,030 --> 00:01:08,730
+أو C لأنه كل نوع من هذه الأنواع لها طريقة في
+
+17
+00:01:08,730 --> 00:01:13,690
+التعامل والعلاج. الشغلة الثانية: ممكن نعمل Screen
+
+18
+00:01:13,690 --> 00:01:18,030
+للناس اللي بيشتغلوا بالمجال الطبي لأنهم في high
+
+19
+00:01:18,030 --> 00:01:22,830
+risk للإصابة، فممكن نعمل لهم الفحص من باب الاطمئنان
+
+20
+00:01:22,830 --> 00:01:25,810
+عليهم، زي الأطباء والممرضين أو أطباء الأسنان.
+
+21
+00:01:25,810 --> 00:01:32,530
+بنعمل لهم هذا الفحص كـ screen. الشغلة الثالثة: الآن في
+
+22
+00:01:32,530 --> 00:01:37,130
+بنك الدم، أي وحدة دم قبل ما تنتقل من المريض لازم
+
+23
+00:01:37,130 --> 00:01:40,110
+نكون متأكدين على الـ Hepatitis والـ HIV كمان، فيها
+
+24
+00:01:40,110 --> 00:01:43,350
+لأنه زي ما أنتم عارفين هي Blood Born Diseases،
+
+25
+00:01:43,350 --> 00:01:46,730
+أمراض بتعيش في الدم وبتنتقل عن طريق الـ Blood
+
+26
+00:01:46,730 --> 00:01:50,430
+Transfusion، فإحنا ما بدنا ننقل المرض وإنما بدنا
+
+27
+00:01:50,430 --> 00:01:57,010
+نمنع انتشاره. طيب، الشغلة الرابعة: الآن Hepatitis B
+
+28
+00:01:57,010 --> 00:02:02,230
+مثلاً صار له Vaccine، فالآن بعد ما يتطعم الشخص بالـ
+
+29
+00:02:02,230 --> 00:02:07,050
+«هيبوتايتس B»، ممكن أنا أقول طبيعي هيكون عنده
+
+30
+00:02:07,050 --> 00:02:10,790
+Antibodies، فأنا ممكن أشيك عليه هل فعلاً كون
+
+31
+00:02:10,790 --> 00:02:14,870
+Antibodies، وهل الـ Antibodies هذه protective، يعني
+
+32
+00:02:14,870 --> 00:02:18,070
+لأنه كل… يعني ممكن كل واحد يكون Antibodies لكن
+
+33
+00:02:18,070 --> 00:02:20,710
+مش شرط أنه تكون الـ Antibodies اللي تطورت عند هذا
+
+34
+00:02:20,710 --> 00:02:23,030
+الشخص وصلت لـ level أنه تعمله protection من
+
+35
+00:02:23,030 --> 00:02:28,430
+الإصابة، تعمله حماية من العدوى. فإحنا ممكن نشوف الناس
+
+36
+00:02:28,430 --> 00:02:31,610
+اللي أخدت الـ Hepatitis Vaccine، هل كوّنت
+
+37
+00:02:31,610 --> 00:02:38,170
+Antibodies بالشكل الكافي ولا لأ. طيب، نلاحظ طبعاً
+
+38
+00:02:38,170 --> 00:02:40,730
+find out if a hepatitis virus infection is the
+
+39
+00:02:40,730 --> 00:02:43,510
+cause of abnormal liver function test. يعني واحد
+
+40
+00:02:43,510 --> 00:02:47,350
+عنده أعراض، مشاكل في الـ liver، عنده abnormal liver
+
+41
+00:02:47,350 --> 00:02:50,670
+function test. طب نعمل فحوصات الـ Viral Hepatitis
+
+42
+00:02:50,670 --> 00:02:53,910
+عشان نشوف هل الـ Viral Hepatitis هو السبب. نيجي
+
+43
+00:02:53,910 --> 00:03:00,250
+لبداية الـ Hepatitis A Virus. أول
+
+44
+00:03:00,250 --> 00:03:05,210
+حاجة هي طبعاً نيجي لخصائص Hepatitis A Virus. طبعاً هو
+
+45
+00:03:05,210 --> 00:03:09,910
+النوع الأكثر شيوعاً اللي بيصيب الأطفال. عبارة عن زي
+
+46
+00:03:09,910 --> 00:03:14,570
+ما قلنا RNA Virus. الـ Incubation Period لإله قصيرة،
+
+47
+00:03:14,570 --> 00:03:19,940
+من أسبوعين إلى ست أسابيع. نيجي لـ Mode of
+
+48
+00:03:19,940 --> 00:03:24,680
+Transmission. كيف بينتقل الفيروس؟ هذا الفيروس مختلف
+
+49
+00:03:24,680 --> 00:03:29,440
+عن الـ B والـ C في أنه بينتقل Fecal Oral Route،
+
+50
+00:03:29,440 --> 00:03:33,380
+ممكن ينتقل من إنسان لإنسان عن طريق الـ
+
+51
+00:03:33,380 --> 00:03:36,260
+Contaminated Food أو الـ Water، عن طريق الـ Direct
+
+52
+00:03:36,260 --> 00:03:42,440
+Contact مع إنسان مصاب. الفيروس هذا بيظهر، إحنا قلنا
+
+53
+00:03:42,440 --> 00:03:46,200
+الـ Incubation Period من أسبوعين إلى ست أسابيع. الآن
+
+54
+00:03:46,200 --> 00:03:52,240
+بيبدأ الفيروس يظهر في الـ stool بعد أسبوعين من الـ
+
+55
+00:03:52,240 --> 00:03:56,320
+infection حتى بدون ما تظهر الأعراض. ففي هذه الفترة
+
+56
+00:03:56,320 --> 00:03:59,620
+بيبقى الشخص Infected بدون ما تظهر عليه أعراض، وهي
+
+57
+00:03:59,620 --> 00:04:08,390
+مشكلته يعني. الفيروس ممكن يصيب أكثر من شخص في نفس
+
+58
+00:04:08,390 --> 00:04:11,730
+البيت، وبعدين تبدأ تظهر الأعراض. يوم ما تظهر الأعراض،
+
+59
+00:04:11,730 --> 00:04:16,730
+إنت سهل تعزل الإنسان المصاب وتحجريه، لكن المشكلة في
+
+60
+00:04:16,730 --> 00:04:19,130
+الفترة اللي قبل، هي فترة الـ incubation period اللي
+
+61
+00:04:19,130 --> 00:04:23,510
+بيكون فيها الفيروس معدي. طبعاً أكثر الناس عرضة هم
+
+62
+00:04:23,510 --> 00:04:27,370
+الأطفال، وغالباً كل ما كان السن أصغر كل ما كانت
+
+63
+00:04:27,370 --> 00:04:30,930
+الأعراض أقل حدة. يعني لو أصيب كبار، هذا بيكون متأكد.
+
+64
+00:04:30,930 --> 00:04:34,670
+طيب، الـ infective dose لهذا الفيروس قليلة، بمعنى إنه
+
+65
+00:04:34,670 --> 00:04:37,370
+كمية بسيطة من الفيروس ممكن تعمل الـ infection.
+
+66
+00:04:38,350 --> 00:04:42,790
+ملاحظات أخرى على الفيروس: أنه نادر أو غالباً ما
+
+67
+00:04:42,790 --> 00:04:45,350
+ينتقل عن طريق الـ blood، بينتقل عن طريق زي ما
+
+68
+00:04:45,350 --> 00:04:49,690
+قلت لكم، فecal الـ oral route. ما بيصير chronic لأنه
+
+69
+00:04:49,690 --> 00:04:55,470
+عادة بتيجي الـ infection، بتظهر الأعراض acute، بعد
+
+70
+00:04:55,470 --> 00:04:59,970
+هيك بتعافى المريض لحاله. acute, there is no chronic
+
+71
+00:04:59,970 --> 00:05:02,810
+carrier state of care. يعني ما فيش عندي واحد carrier
+
+72
+00:05:02,810 --> 00:05:06,630
+أقول إنه هذا carrier للمرض وبيعدي وممكن يعمل مشاكل،
+
+73
+00:05:06,630 --> 00:05:11,540
+لأ، هو أعراض وبتنتهي مع انتهاء الأعراض بيكون الفيروس
+
+74
+00:05:11,540 --> 00:05:17,820
+تقريباً انتهى. شغلة ثانية: الأنواع الثانية من الفيروس
+
+75
+00:05:17,820 --> 00:05:21,920
+الـ B والـ C ممكن تكون يعني مسببة للـ
+
+76
+00:05:21,920 --> 00:05:26,040
+Hepatocellular Carcinoma، لكن هذا لأ يعني غالباً ما
+
+77
+00:05:26,040 --> 00:05:28,900
+بيعملش أعراض خطيرة أو ما بيكونش مسبب للـ
+
+78
+00:05:28,900 --> 00:05:33,180
+Hepatocellular Carcinoma على المدى الطويل. طيب، هنا
+
+79
+00:05:33,180 --> 00:05:37,800
+في ملاحظة مهمة: الفيروس هذا لو أصيب فيه الإنسان مرة
+
+80
+00:05:37,800 --> 00:05:42,380
+واحدة يعني، لا يشترط إنه يأخذ Protection طول الحياة، ممكن
+
+81
+00:05:42,380 --> 00:05:46,640
+يصاب فيه مرة أخرى. الـ IgG تبعته ما بتظل طول الحياة.
+
+82
+00:05:46,640 --> 00:05:50,220
+مهم جداً الـ Personal Hygiene، الـ Hand Washing،
+
+83
+00:05:50,220 --> 00:05:55,760
+والأشياء هذه عشان نحد من انتقاله للناس. الـ Signs
+
+84
+00:05:55,760 --> 00:06:01,180
+بتاعة الـ Hepatitis تقريباً يعني مشتركة. Abdominal
+
+85
+00:06:01,180 --> 00:06:05,560
+pain، بيصير Jaundice، صفار شديد في العين وفي الجلد،
+
+86
+00:06:05,560 --> 00:06:12,120
+Nausea or vomiting، بيصير Weight loss، Itchy skin،
+
+87
+00:06:12,120 --> 00:06:15,300
+نتيجة وجود الفيروس في الـ في الـ blood، بيعمل حكة
+
+88
+00:06:15,300 --> 00:06:21,440
+شديدة، بيعمل انتفاخ في الـ abdomen. طيب،
+
+89
+00:06:21,440 --> 00:06:24,430
+نيجي للـ Lab diagnosis. غالباً إيه بنات الـ Lab
+
+90
+00:06:24,430 --> 00:06:27,670
+diagnosis يعني؟ هو إذا طفل ظهرت عليه أعراض الصفار،
+
+91
+00:06:27,670 --> 00:06:31,690
+بيعملوا له فحص الـ urine. الـ urine عادة هنلاقي فيه الـ
+
+92
+00:06:31,690 --> 00:06:34,890
+Bilirubin عالي. إذا لاقينا الـ Bilirubin عالي ممكن
+
+93
+00:06:34,890 --> 00:06:38,230
+الدكتور يطلب له Liver enzymes، وخلاص بيتأكد إنه مريض
+
+94
+00:06:38,230 --> 00:06:43,930
+Hepatitis A. وبالطفل يعني بتحمي عن أشياء معينة،
+
+95
+00:06:43,930 --> 00:06:48,030
+بيقولوا له يعني ابعد عن الأشياء اللي فيها دهون، خليك
+
+96
+00:06:48,030 --> 00:06:51,070
+على الأشياء اللي فيها السكريات، على أساس إنه يعني
+
+97
+00:06:51,070 --> 00:06:55,660
+ما نرهقش الـ liver. البروتينات برضه مهمة، البروتينات
+
+98
+00:06:55,660 --> 00:06:59,500
+بدون دهون عشان يكوّن أجسام مضادة ويتغلب على المرض.
+
+99
+00:06:59,500 --> 00:07:03,840
+فبالتالي يعني من خلال فحوصات الـ chemistry عند
+
+100
+00:07:03,840 --> 00:07:07,260
+الأطفال، من الـ urine والـ chemistry بتتم تشخيصه، تمام؟
+
+101
+00:07:07,260 --> 00:07:11,140
+لكن لو أصاب الـ adult، يعني هنا بيصير هل هو B ولا A،
+
+102
+00:07:11,140 --> 00:07:15,720
+فممكن نلجأ لإنه نحدد الـ Antibodies ذاتها عشان نعرف
+
+103
+00:07:15,720 --> 00:07:19,520
+إذا كان مثلاً Hepatitis A ولا Hepatitis B ولا
+
+104
+00:07:19,520 --> 00:07:24,520
+Hepatitis C. مثلاً، ممكن ينعملوا زي الـ RIA أو الـ
+
+105
+00:07:24,520 --> 00:07:29,620
+ELISA عشان يحدد الـ IgM خلال أسبوعين أو تلت أسابيع
+
+106
+00:07:29,620 --> 00:07:35,020
+من الـ infection. وبعد فترة ممكن نعمل فحص الـ IgG.
+
+107
+00:07:35,020 --> 00:07:39,420
+في فحص بيسمونه Rapid Assay غير الـ ELISA اللي هو
+
+108
+00:07:39,420 --> 00:07:45,500
+الـ Strip هذا اللي حكينا عنه أو هناخده. الـ Strip
+
+109
+00:07:45,500 --> 00:07:48,980
+هذا بتحط الـ Drop، شبه فحص الحمل، فبيطلع معكِ إذا
+
+110
+00:07:48,980 --> 00:07:51,700
+كانت النتيجة، بيطلع معكِ خطين إذا كانت positive،
+
+111
+00:07:51,700 --> 00:07:57,120
+فبيطلع معكِ خط واحد إذا كانت negative. تمام، هذا
+
+112
+00:07:57,120 --> 00:08:01,640
+بيسموه الـ Rapid Assay لأنه فحص سريع وبسرعة بيعطيني
+
+113
+00:08:01,640 --> 00:08:05,320
+نتيجة. ممكن نعمل detection للفيروس في الـ feces عن
+
+114
+00:08:05,320 --> 00:08:08,940
+طريق الـ electron microscope. ممكن نعزل الفيروس
+
+115
+00:08:08,940 --> 00:08:12,320
+يعني أنا قلت الطريقتين هدول لأنهم يعني تكلفتهم مش
+
+116
+00:08:12,320 --> 00:08:14,920
+دائماً متاحين يعني في الـ clinical laboratory أنه
+
+117
+00:08:14,920 --> 00:08:20,260
+نعزله بـ cell culture ونعمل diagnosis له، تمام؟
+
+118
+00:08:20,260 --> 00:08:27,680
+نيجي للـ Hepatitis B virus. الـ Hepatitis B virus
+
+119
+00:08:27,680 --> 00:08:33,340
+عبارة عن DNA virus. فيه منه شكلان، فيه اللي هو
+
+120
+00:08:33,340 --> 00:08:38,080
+spherical particles، وفي عندي filamentous particles.
+
+121
+00:08:38,080 --> 00:08:41,880
+الـ incubation period خذوا بالكم، هناك قلنا أسابيع،
+
+122
+00:08:41,880 --> 00:08:46,200
+هنا من شهرين إلى ست شهور، من خمسين إلى مئة وثمانين
+
+123
+00:08:46,200 --> 00:08:46,520
+يوم.
+
+124
+00:08:49,620 --> 00:08:54,140
+طريقة الـ Transmission طبعاً خلال الولادة، Vertical
+
+125
+00:08:54,140 --> 00:08:58,000
+Transmission من الـ mother للـ baby. ممكن Sexual
+
+126
+00:08:58,000 --> 00:09:02,180
+Transmission، عن طريق الـ Blood Transfusion، Sharing
+
+127
+00:09:02,180 --> 00:09:07,200
+Contaminated Needles or Other Equipment. Parental
+
+128
+00:09:07,200 --> 00:09:09,940
+Transmission اللي هو عن طريق الأدوات هذه، تخريم
+
+129
+00:09:09,940 --> 00:09:13,240
+الـ ودن أو التاتو أو الأشياء اللي مثلها، ممكن لو كانتش
+
+130
+00:09:13,240 --> 00:09:16,440
+الأدوات معقمة، ينتقل عن طريقها.
+
+131
+00:09:19,270 --> 00:09:23,510
+الـ Symptoms تقريباً نفس الـ Symptoms بتاعت A، بس
+
+132
+00:09:23,510 --> 00:09:26,450
+هذه مشكلتها إنها بتكون أشد وبتطول، يعني بتقعد فترة
+
+133
+00:09:26,450 --> 00:09:30,490
+أطول. Sharp, Mild, Flu-like illness, Nausea,
+
+134
+00:09:30,570 --> 00:09:32,930
+Fatigue, Abdominal pain, Weight loss, Joints,
+
+135
+00:09:33,210 --> 00:09:40,990
+Itchy skin. الآن
+
+136
+00:09:40,990 --> 00:09:44,790
+بقول لك إذا الشخص يعني ظل معه Hepatitis B لعدة
+
+137
+00:09:44,790 --> 00:09:49,180
+سنوات ممكن يصير عنده أحد الـ Complications هذه. ممكن
+
+138
+00:09:49,180 --> 00:09:53,720
+يتحول لـ Chronic. تمام، ممكن يصير عنده Liver
+
+139
+00:09:53,720 --> 00:09:57,960
+cirrhosis، ممكن يتحول ل… يعني ممكن يكون مسبب للـ
+
+140
+00:09:57,960 --> 00:10:00,640
+hepatocellular carcinoma، ممكن يتحول لـ Liver
+
+141
+00:10:00,640 --> 00:10:05,900
+cancer. هنا حاطط لك بس صورة للـ Healthy liver. بعد
+
+142
+00:10:05,900 --> 00:10:11,120
+هيك المرحلة الأولى، يعني تبدأ بداية تليف بسيط
+
+143
+00:10:11,120 --> 00:10:16,410
+للكبد، من الـ inflammation، فببدأ يصير Fibrosis في الـ
+
+144
+00:10:16,410 --> 00:10:20,290
+Liver. بعد هيك بيصير Cirrhosis للـ Liver. طبعاً اللي
+
+145
+00:10:20,290 --> 00:10:25,570
+بتلاقي معظم الـ Liver استبدلت بخلايا ميتة، فبالتالي
+
+146
+00:10:25,570 --> 00:10:29,010
+بتقل وظيفتها بشكل كتير كبير. بعد هيك ممكن
+
+147
+00:10:29,010 --> 00:10:36,590
+يصير Liver cancer. نيجي
+
+148
+00:10:36,590 --> 00:10:40,120
+للـ Lab diagnosis. الـ Lab Diagnosis أول حاجة ممكن
+
+149
+00:10:40,120 --> 00:10:43,460
+نعمل فحوصات الـ Chemistry اللي هي Liver function
+
+150
+00:10:43,460 --> 00:10:49,360
+tests. ممكن طبعاً بتكون مرتفعة. Liver function tests
+
+151
+00:10:49,360 --> 00:10:53,620
+كلها. ممكن ندور على الـ Hepatitis B surface
+
+152
+00:10:53,620 --> 00:10:57,340
+Antigen. إذا الـ Hepatitis B surface Antigen موجود،
+
+153
+00:10:57,340 --> 00:11:00,960
+بأكد الـ diagnosis. ممكن نختبره عن طريق الـ ELISA
+
+154
+00:11:00,960 --> 00:11:05,750
+أو الـ RIA. في عندنا الـ Serological Testing هنحكي
+
+155
+00:11:05,750 --> 00:11:08,750
+عنها، يعني إللنا فيها كلام كتير، اللي هي نعرف الـ
+
+156
+00:11:08,750 --> 00:11:11,930
+Hepatitis Markers. هذا الـ Serological Testing بوضح
+
+157
+00:11:11,930 --> 00:11:17,110
+عندي المريض في أي مرحلة من مراحل المرض. ممكن نحدد
+
+158
+00:11:17,110 --> 00:11:22,570
+الـ Viral DNA Load باستخدام فحوصات الـ PCR. ممكن
+
+159
+00:11:22,570 --> 00:11:29,190
+نعمل Liver Biopsy وPCR من الـ Liver نفسها. طيب،
+
+160
+00:11:29,190 --> 00:11:32,570
+نحكي عن الـ Hepatitis Markers. هذه إيش الفائدة منها؟
+
+161
+00:11:32,570 --> 00:11:35,930
+الـ Hepatitis Markers بتقول لي أو بتخبرني إيش وضع
+
+162
+00:11:35,930 --> 00:11:39,210
+المرض عند هذا الشخص، عند هذا المريض. يعني هل هو
+
+163
+00:11:39,210 --> 00:11:43,570
+acute، هل هو مريض chronic، هل هو معدي، مش معدي، and so
+
+164
+00:11:43,570 --> 00:11:49,270
+on. تمام. أول واحد: الـ Hepatitis B Surface Antigen،
+
+165
+00:11:49,270 --> 00:11:55,830
+هذا عبارة عن Antigen موجود على الـ Surface بتاع
+
+166
+00:11:55,830 --> 00:12:02,420
+الفيروس. تمام. بيظهر من شهرين إلى ست شهور بعد الـ
+
+167
+00:12:02,420 --> 00:12:06,540
+infection. إذا كان موجود وpositive، معنى الكلام إن
+
+168
+00:12:06,540 --> 00:12:10,080
+الشخص هذا الـ virus موجود عنده، إما acute أو
+
+169
+00:12:10,080 --> 00:12:13,820
+chronic. طيب،
+
+170
+00:12:13,820 --> 00:12:17,880
+هلا قيت الـ surface antigen هيتكون له Antibody،
+
+171
+00:12:17,880 --> 00:12:25,600
+هيبدأ الجسم يكون له Antibody. إذا ارتفع الـ surface
+
+172
+00:12:25,600 --> 00:12:30,600
+Antibody وصار الـ Antigen negative، معنى الكلام إنه
+
+173
+00:12:30,600 --> 00:12:34,520
+هذا الشخص شفي تماماً، تعافى، يعني الفيروس مش موجود
+
+174
+00:12:34,520 --> 00:12:37,300
+عنده، ولا chronic ولا حاجة، انتهى الفيروس من عنده.
+
+175
+00:12:37,300 --> 00:12:42,100
+إذا الشرط إنه ينتهي الفيروس إنه يكون الـ Hepatitis
+
+176
+00:12:42,100 --> 00:12:48,560
+B surface antigen negative. إذا كان positive، معنى
+
+177
+00:12:48,560 --> 0
+
+223
+00:16:00,680 --> 00:16:06,300
+شفاء وإنما يُعتبر أو يدل على أن الفيروس صار له
+
+224
+00:16:06,300 --> 00:16:09,940
+control عن طريق الـImmune System لكن لازال
+
+225
+00:16:09,940 --> 00:16:14,240
+الفيروس موجود وممكن يظل سنوات طويلة الفيروس بهذا
+
+226
+00:16:14,240 --> 00:16:20,760
+الوضع أن الـHepatitis B Antibody موجود ومرتفع
+
+227
+00:16:20,760 --> 00:16:25,360
+وموقف نشاط الفيروس، عيار هذا انخفض، هتلاقي أن
+
+228
+00:16:25,360 --> 00:16:32,190
+الفيروس ممكن يرجع يتنشط. تمام يا بنات؟ إذا إيش فيه
+
+229
+00:16:32,190 --> 00:16:37,190
+هنا؟ زي ما قلنا أن انخفاض الانتيجن أو أن الانتيجن
+
+230
+00:16:37,190 --> 00:16:41,010
+هذا راح لا يعني أنه شفاء، but this virus is being
+
+231
+00:16:41,010 --> 00:16:43,310
+controlled by the immune system and cannot
+
+232
+00:16:43,310 --> 00:16:50,230
+replicate well anymore. مش هيتكاثر بشكل أكبر، وهذا
+
+233
+00:16:50,230 --> 00:16:56,350
+نفس الكلام هيتكرر عن الانتيجن. هنا عندك هذا الـCurve
+
+234
+00:16:56,350 --> 00:16:59,710
+بيبين الـHepatitis Markers وارتفاعها، كل واحد في
+
+235
+00:16:59,710 --> 00:17:04,390
+أي مرحلة، ممكن يرتفع. بداية الـHepatitis B Surface
+
+236
+00:17:04,390 --> 00:17:09,050
+Antigen بيبدأ يرتفع، تمام؟ بدنا نأخذ الـAntigen و
+
+237
+00:17:09,050 --> 00:17:12,450
+الـAntibody بتاعه ونشوف إيش بيصير هلقيت؟ وين الـ
+
+238
+00:17:12,450 --> 00:17:17,130
+Hepatitis B Surface Antibody هيه؟ هذا اللي لونه
+
+239
+00:17:17,130 --> 00:17:23,330
+كحلي، اللي هو الـHepatitis B Antibody، كويس؟ هلقيت؟
+
+240
+00:17:23,570 --> 00:17:27,270
+لما بيرتفع الـAntibody، الـAntigen حينتهي، وهذه
+
+241
+00:17:27,270 --> 00:17:33,050
+بعتبرها مرحلة، أش.. مرحلة الشفاء التام، مرحلة أش..
+
+242
+00:17:33,050 --> 00:17:36,950
+مرحلة الشفاء التام، أن الـSurface Antigen انتهى
+
+243
+00:17:36,950 --> 00:17:41,290
+وارتفع الـSurface Antibody، وحيظل مرتفع على طول.
+
+244
+00:17:41,290 --> 00:17:46,910
+طيب، نيجي للـE-Antigen، نفس الشيء، الـAntigen نزل
+
+245
+00:17:46,910 --> 00:17:51,710
+وهيرتفع عندي الـAntibody. طبعاً هذه مش مرحلة شفاء،
+
+246
+00:17:51,710 --> 00:17:55,930
+مرحلة control للفيروس، اللي بيهمني أكثر عشان أحدد
+
+247
+00:17:55,930 --> 00:17:59,730
+أن الشخص فعلاً شفي ولا لأ، الـHepatitis B Surface
+
+248
+00:17:59,730 --> 00:18:02,990
+Antigen هذا هو اللي بيدل على أن الفيروس انتهى ولا
+
+249
+00:18:02,990 --> 00:18:08,190
+لأ. طيب، بعد هتجي عندي الـCore، الـCore في بداية
+
+250
+00:18:08,190 --> 00:18:13,970
+الـAnticore Antibody Hepatitis B، أول شيء هيرتفع
+
+251
+00:18:13,970 --> 00:18:20,990
+عندي الـIgM، تمام؟ هيرتفع عندي الـIgM، وهيبدا ينزل
+
+252
+00:18:20,990 --> 00:18:26,570
+وطبعاً هيرتفع عندي بعد هيك الـIgG، لو أنتو لاحظتو
+
+253
+00:18:26,570 --> 00:18:30,270
+هذا الخط الغامق اللي فوق، هذا بشكل الـIgM مع الـ
+
+254
+00:18:30,270 --> 00:18:34,410
+IgG، يعني هو ما فصل، هو اعتبر Total IgM و IgG
+
+255
+00:18:34,410 --> 00:18:38,370
+فبالتالي مع بداية الارتفاع، هيرتفع، هينزل الـIgM
+
+256
+00:18:38,370 --> 00:18:42,950
+بس الـIgG هيظل مرتفع على طول. إذا في النهاية بتوقع
+
+257
+00:18:42,950 --> 00:18:48,190
+يكون الـCore، أي شخص دخل جسمه الفيروس، هيكون الـ
+
+258
+00:18:48,190 --> 00:18:53,630
+Core Antibody Positive. أي واحد أخذ طعم أو دخل جسمه
+
+259
+00:18:53,630 --> 00:18:57,850
+الفيروس، هيكون الـAntibiotitis B Surface Positive.
+
+260
+00:18:57,850 --> 00:19:02,010
+لما يكون الـAntibiotitis E Positive، معنى الكلام
+
+261
+00:19:02,010 --> 00:19:08,090
+أنه الفيروس Under Control. هذه الفترات الزمنية
+
+262
+00:19:08,090 --> 00:19:13,930
+المتوقعة لارتفاع الـAntibodies. طيب،
+
+263
+00:19:13,930 --> 00:19:18,180
+خلّيني نشوف الآن كل مرحلة من مراحل المرض، مين بيكون
+
+264
+00:19:18,180 --> 00:19:22,020
+فيها Positive و Negative، زي ملخص بشكل أبسط. أول
+
+265
+00:19:22,020 --> 00:19:25,540
+حاجة، مرحلة الـIncubation Period، أنه لسه ما فيه
+
+266
+00:19:25,540 --> 00:19:29,000
+أعراض، هنلاقي على الأكيد Hepatitis B Surface
+
+267
+00:19:29,000 --> 00:19:32,120
+Antigen Positive. إحنا قلنا بيبدأ يظهر من البدايات،
+
+268
+00:19:32,120 --> 00:19:35,680
+يعني ممكن ثلاثة أسابيع من بداية الinfection، يبدأ
+
+269
+00:19:35,680 --> 00:19:39,720
+يعطيني Positive بدون أعراض. الـE ممكن يكون
+
+270
+00:19:39,720 --> 00:19:43,410
+Positive أو Negative، يعني مش كتير من القياس. المهم
+
+271
+00:19:43,410 --> 00:19:46,510
+الـSurface Antigen هو الـPositive. طيب، في مرحلة
+
+272
+00:19:46,510 --> 00:19:50,490
+الـAcute Hepatitis، الـAcute Hepatitis يعني
+
+273
+00:19:50,490 --> 00:19:55,850
+الفيروس موجود ونشط، وبيكاثر، فهتلاقي الـHepatitis
+
+274
+00:19:55,850 --> 00:19:59,770
+Surface Antigen Positive، والـHepatitis E Antigen
+
+275
+00:19:59,770 --> 00:20:03,290
+Positive، لكن الـAntibodies بتاعتهم لسه ما اتكونت
+
+276
+00:20:03,290 --> 00:20:07,850
+لأنه لو اتكونت، هيبدا الفيروس يقل نشاطه، صح؟ مين
+
+277
+00:20:07,850 --> 00:20:10,670
+اللي هيرتفع؟ اللي هو الـCore، اللي زي ما قلتلكم
+
+278
+00:20:10,670 --> 00:20:14,330
+هيعطي دلالة أنه الفيروس موجود في الـAcute
+
+279
+00:20:14,330 --> 00:20:19,370
+Hepatitis. هتلاقي الـCore IgM Positive، وبعد هيك
+
+280
+00:20:19,370 --> 00:20:21,830
+طبعاً الـTotal هيكون Positive، لأني قلتلكم الـ
+
+281
+00:20:21,830 --> 00:20:26,750
+Total بيشمل الـIgM والـIgG، تمام؟ طيب، نيجي
+
+282
+00:20:26,750 --> 00:20:33,270
+للي بعد هالمرحلة، Chronic Carrier. Career معنى
+
+283
+00:20:33,270 --> 00:20:37,630
+الكلام with low infectivity. خلوا بالكم، low
+
+284
+00:20:37,630 --> 00:20:42,130
+infectivity يعني مش معدِ، والفيروس مش نشط. هنلاقي
+
+285
+00:20:42,130 --> 00:20:45,090
+career، يعني الانتيجن لازال موجود، الـsurface
+
+286
+00:20:45,090 --> 00:20:51,170
+antigen لازال موجود، الفيروس موجود طبعاً
+
+287
+00:20:51,170 --> 00:20:55,850
+ما انتهش، الفيروس ليش؟ لأنه الـantibody للـsurface
+
+288
+00:20:55,850 --> 00:21:01,030
+مرتفع، لازال negative. طالما الـHepatitis B Surface
+
+289
+00:21:01,030 --> 00:21:04,550
+Antibody Negative، هيظل الفيروس موجود، وهيكون الشخص
+
+290
+00:21:04,550 --> 00:21:09,170
+هذا carrier. طيب، الـcarrier يا بنات في منه نوعين، Low
+
+291
+00:21:09,170 --> 00:21:11,990
+Infectivity و High Infectivity. طلعوا معايا
+
+292
+00:21:11,990 --> 00:21:15,610
+الحالتين، هدول اللي فوق بعض، إيش بيفرقهم؟ الاثنين
+
+293
+00:21:15,610 --> 00:21:18,570
+carrier، يعني الـHepatitis B Surface Antigen موجود
+
+294
+00:21:18,570 --> 00:21:22,970
+فيهم، تمام؟ والاثنين الـHepatitis B Surface
+
+295
+00:21:22,970 --> 00:21:26,230
+Antibody مش موجود، لأنه لو موجود، هيبطل carrier و
+
+296
+00:21:26,230 --> 00:21:31,620
+هنعدي في مرحلة الشفاء، صح؟ اللي بيفرقوا عن بعض، الـ
+
+297
+00:21:31,620 --> 00:21:36,620
+Hepatitis E Early Antigen، الـHepatitis، عفواً، الـ
+
+298
+00:21:36,620 --> 00:21:39,920
+E-Antigen. هلقيت الـE-Antigen في الـLow
+
+299
+00:21:39,920 --> 00:21:44,420
+Infectivity Negative، يعني هذا الشخص بيفرق عن هذا
+
+300
+00:21:44,420 --> 00:21:50,840
+أنه الفيروس في الحالة الأولى مش نشط، وما بيتكاثر
+
+301
+00:21:50,840 --> 00:21:53,980
+لأن الـE-Antigen Negative، والـE-Antibody
+
+302
+00:21:53,980 --> 00:21:59,920
+Positive، تمام؟ بينما الحالة الثانية، الـE-antigen
+
+303
+00:21:59,920 --> 00:22:04,980
+Positive، والـE-antibody Negative، فبالتالي الشخص
+
+304
+00:22:04,980 --> 00:22:10,700
+هذا بيقول "highly infective". ليش؟ لأنه ما عنده E
+
+305
+00:22:10,700 --> 00:22:13,900
+-antibody. الاثنين chronic، والاثنين عندهم الفيروس، لكن
+
+306
+00:22:13,900 --> 00:22:17,720
+واحد في عندهم الفيروس نشط، وبيتكاثر، وبيعدي، وواحد لأ.
+
+307
+00:22:18,680 --> 00:22:22,660
+بالنسبة للـCore، قلت لكم هيكون موجود، بداية في الـ
+
+308
+00:22:22,660 --> 00:22:26,020
+Acute، بيكون Positive، الـIgM. بعد هيك بيظل عندي الـ
+
+309
+00:22:26,020 --> 00:22:28,520
+Total، اللي هو زي ما قلت لكم، الـIgG هو اللي بيكون
+
+310
+00:22:28,520 --> 00:22:33,500
+Positive. مرحلة الـConvalescence، مرحلة التعافي،
+
+311
+00:22:33,500 --> 00:22:39,240
+هتلاقي كل شيء عنده Negative، أن الشخص شفي، ويعني بطل
+
+312
+00:22:39,240 --> 00:22:42,740
+طيب، ليش الـAntibodies هتلاقيها Negative؟ يعني هي
+
+313
+00:22:42,740 --> 00:22:48,550
+الآن، في عندي بداية تكوين للـAntibody، لكن لسه مش
+
+314
+00:22:48,550 --> 00:22:52,210
+ملموسة، يعني انتهى الـAntigen، لكن لسه الـAntibody
+
+315
+00:22:52,210 --> 00:22:55,650
+مش كتير detectable في الـBlood. بس مين اللي موجود؟
+
+316
+00:22:55,650 --> 00:23:01,530
+اللي هو الـCore، Past Infection، يعني هذه مرحلة، أول
+
+317
+00:23:01,530 --> 00:23:04,050
+ما بيبدأ الشخص يتعافى من المرض، لسه الـAntibodies
+
+318
+00:23:04,050 --> 00:23:07,370
+متكونش عالية ومميزة في الـSerum، اللي هو اللي
+
+319
+00:23:07,370 --> 00:23:12,630
+بتعمل بيه Tests. Surface Antibody بيكونش واضحة. هلقيت واحدة
+
+320
+00:23:12,630 --> 00:23:17,270
+اتعافت وخلاص، تمام، ما فيش عندها مشكلة، هتلاقي الـ
+
+321
+00:23:17,270 --> 00:23:21,150
+Surface Antibody ارتفع، معنى الكلام أن هذا الشخص
+
+322
+00:23:21,150 --> 00:23:25,350
+اتعافى تماماً، وانتهى الـVirus من عنده، وبرضه هتلاقي
+
+323
+00:23:25,350 --> 00:23:28,470
+الـCore Positive. طيب، واحد أخذ الـVaccine، مين
+
+324
+00:23:28,470 --> 00:23:34,330
+هلاقي عنده Positive؟
+
+325
+00:23:34,330 --> 00:23:38,610
+نيجي الآن للسؤال: هل Hepatitis B Virus له تطعيم؟
+
+326
+00:23:38,610 --> 00:23:43,700
+صحيح، Hepatitis B Virus له تطعيم. طبعاً التطعيم عبارة
+
+327
+00:23:43,700 --> 00:23:46,540
+عن Hepatitis B Surface Antigen، بيحضروه بالـ
+
+328
+00:23:46,540 --> 00:23:50,360
+Recombinant DNA Technology. الآن الأطفال يعني
+
+329
+00:23:50,360 --> 00:23:54,460
+متعلمين، بيتعاملوا لهم برنامج خاص لتطعيم الـ
+
+330
+00:23:54,460 --> 00:23:58,040
+Hepatitis. ولو في واحد كبير من الأجيال اللي ما
+
+331
+00:23:58,040 --> 00:24:00,480
+اتعالج قبل هيك، يفترض أن يدور على حاله، ويأخذ
+
+332
+00:24:00,480 --> 00:24:07,090
+التطعيم من باب الوقاية. عادة بعد التطعيم، تأخذ عينة
+
+333
+00:24:07,090 --> 00:24:09,790
+الدم، عشان نشوف هل التطعيم شغل كويس، وكوّن
+
+334
+00:24:09,790 --> 00:24:13,350
+antibodies، وعطى حماية ولا لأ. على الأقل التطعيم
+
+335
+00:24:13,350 --> 00:24:17,670
+بيعطي حماية، أو بيظل الـTiter للـAntibody لمدة خمس
+
+336
+00:24:17,670 --> 00:24:20,610
+سنين على الأقل، وإن كان يعني بيعطي حماية لفترة أكبر.
+
+337
+00:24:20,610 --> 00:24:25,090
+نقل الـHepatitis C Virus، طبعاً هذا الـVirus اللي
+
+338
+00:24:25,090 --> 00:24:28,750
+هو يعني مشكلته أنه ما لهش تطعيم، وأخطر من Hepatitis
+
+339
+00:24:28,750 --> 00:24:35,690
+B. Hepatitis C Incubation period من 15 إلى 150 يوماً،
+
+340
+00:24:35,690 --> 00:24:42,130
+وعبارة عن RNA Virus. نيجي للـTransmission of
+
+341
+00:24:42,130 --> 00:24:45,590
+Hepatitis C Virus. بينتقل تقريباً بنفس الطرق اللي
+
+342
+00:24:45,590 --> 00:24:48,130
+ب ينتقل فيها Hepatitis B، وإن كان الـSexual
+
+343
+00:24:48,130 --> 00:24:50,710
+Transmission، والـVertical Transmission من الـ
+
+344
+00:24:50,710 --> 00:24:54,210
+mother للـbaby، والـbreast feeding أو الـbreast
+
+345
+00:24:54,210 --> 00:24:59,870
+milk مش كتير مؤكد أنه بينتقل عن طريقهم. الآن معظم
+
+346
+00:24:59,870 --> 00:25:02,730
+فيه، يعني عدد كبير من الناس اللي بياخدوا الـ
+
+347
+00:25:02,730 --> 00:25:06,590
+infection، بتحول إلى chronic من 75 إلى 85% منهم،
+
+348
+00:25:06,590 --> 00:25:11,870
+بتحول إلى chronic. تقريباً 20% من المصابين بيصير لهم
+
+349
+00:25:11,870 --> 00:25:15,990
+يعني recovery، لحالهم بيطيبوا، بتكون antibodies، و
+
+350
+00:25:15,990 --> 00:25:20,360
+بتعافوا من المرض بدون مشاكل خلال ستة شهور. لكن هذا لا
+
+351
+00:25:20,360 --> 00:25:24,580
+يعني أنه مش راح ينصاب فيه كمان مرة، لأنه هو زي ما
+
+352
+00:25:24,580 --> 00:25:27,540
+أنتوا عارفين، فيروس بيعمل Zero-conversion، وبيغير
+
+353
+00:25:27,540 --> 00:25:31,420
+نفسه، وهذا اللي خلاه فيه صعوبة لحدوث تطعيم، دلوقتي
+
+354
+00:25:31,420 --> 00:25:33,560
+في الفيروس. طبعاً هي نفس الـProgress، زي ما قلنا،
+
+355
+00:25:33,560 --> 00:25:38,020
+Normal liver. لو كان فيه chronic hepatitis، هتبدأ الـ
+
+356
+00:25:38,020 --> 00:25:40,640
+liver تتغير، وتصبح فيها fibrosis، وبعدين cirrhosis،
+
+357
+00:25:40,640 --> 00:25:47,640
+وبعدها ممكن تتحول لـHepatocellular Carcinoma. الـ
+
+358
+00:25:47,640 --> 00:25:52,250
+diagnosis ممكن نعمل فحصات serology، لكن ما عندي فحصات
+
+359
+00:25:52,250 --> 00:25:57,050
+زي الـHepatitis B، تقول لمين في أي مرحلة، acute ولا
+
+360
+00:25:57,050 --> 00:26:01,170
+chronic، وإنما بنستخدم الـviral load، يعني بيشوفوا
+
+361
+00:26:01,170 --> 00:26:06,310
+كمية الفيروس في الـblood عن طريق الـPCR. الطريقة
+
+362
+00:26:06,310 --> 00:26:11,210
+الثانية اللي هي using molecular nucleic acid، زي
+
+363
+00:26:11,210 --> 00:26:16,030
+real-time PCR، وrecombinant immunoblot assay. في
+
+364
+00:26:16,030 --> 00:26:20,430
+عندي transcription-mediated amplification, branched
+
+365
+00:26:20,430 --> 00:26:25,050
+DNA. طبعاً هذه الفحصات هي اللي قلتلكم عنها، هي من
+
+366
+00:26:25,050 --> 00:26:28,530
+خلالها ما بتحدد بس إذا كان الشخص مصاب ولا لأ، برضه
+
+367
+00:26:28,530 --> 00:26:31,890
+بتحدد كمية الـvirus الموجودة في الـblood، اللي هو
+
+368
+00:26:31,890 --> 00:26:38,300
+الهيباتيتاية C viral load. الآن لو إحنا عملنا فحص الـ
+
+369
+00:26:38,300 --> 00:26:42,280
+ELISA، أو بتقنيات المناعية الـserology العادية، طلع
+
+370
+00:26:42,280 --> 00:26:45,240
+معايا Negative، فهو Negative. الآن إذا طلع معايا
+
+371
+00:26:45,240 --> 00:26:50,120
+Positive، بدي أؤكد عن طريق الـRNA، إذا كان الـviral
+
+372
+00:26:50,120 --> 00:26:54,580
+RNA Positive، يعني الشخص هذا for sure مصاب. إذا طلع
+
+373
+00:26:54,580 --> 00:26:58,760
+الـviral RNA Negative، بعمل recombinant immunoblot
+
+374
+00:26:58,760 --> 00:27:04,590
+assay. إذا كانت Positive، يعني كان فيه فيروس، وصار لها
+
+375
+00:27:04,590 --> 00:27:11,350
+recovery، صار يعني صار شفاء منها، وانتهت. وإذا طلعت
+
+376
+00:27:11,350 --> 00:27:15,310
+الـrecombinant immunoblot assay Negative، معنى
+
+377
+00:27:15,310 --> 00:27:19,850
+الكلام أن الفحص هذا كان false Positive، لأن لو
+
+378
+00:27:19,850 --> 00:27:25,580
+تلاحظتو، هذه Negative، والـRNA Negative. من الـ
+
+379
+00:27:25,580 --> 00:27:29,320
+Positive الوحيدة كانت الـELISA، أو الـSerological
+
+380
+00:27:29,320 --> 00:27:33,480
+Techniques، بتكون False Negative، يعني الـNegative
+
+381
+00:27:33,480 --> 00:27:36,580
+من الأساس بأعتبرها Negative. الـPositive بأكدها عن
+
+382
+00:27:36,580 --> 00:27:40,720
+طريق الـRNA، وعن طريق الـRecombinant Immunoblot
+
+383
+00:27:40,720 --> 00:27:44,360
+الأساسي.
+
+384
+00:27:44,360 --> 00:27:47,880
+في عندي، زي ما قلتلكم، غير الـViral Load، ممكن نعمل
+
+385
+00:27:47,880 --> 00:27:51,300
+liver function test، ممكن نعمل liver biopsy عشان
+
+386
+00:27:51,300 --> 00:27:56,210
+نشوف الـ... في عندي نوعين من الـviruses، اللي هو non
+
+387
+00:27:56,210 --> 00:27:59,130
+-A، non-B hepatitis viruses. في عندي Hepatitis D
+
+388
+00:27:59,130 --> 00:28:04,590
+virus. الـHepatitis D virus مش شائع، وهذا الـvirus
+
+389
+00:28:04,590 --> 00:28:09,930
+بيتميّز بأنه بعيش فقط على Hepatitis B، يعني ما بعيش
+
+390
+00:28:09,930 --> 00:28:13,670
+إلا فيه، عند إنسان مصاب بـHepatitis B، يعني لحاله
+
+391
+00:28:13,670 --> 00:28:17,990
+ما بقدرش أعيش، ليش؟ لأنه بيستفيد من الـEnvelope
+
+392
+00:28:17,990 --> 00:28:21,590
+protein عشان يعمل replication تاع Hepatitis B، يعني
+
+393
+00:28:21,590 --> 00:28:25,010
+بيأخذ Envelope protein
+
+445
+00:32:03,230 --> 00:32:07,370
+western blot، and recombinant immunoblot assay
+
+446
+00:32:07,370 --> 00:32:10,750
+الـ western blot تعتبر الـ gold standard للـ diagnosis
+
+447
+00:32:10,750 --> 00:32:17,930
+للهيباطية للفيروس الـ HIV، فيروس نيجي للـ Antigen
+
+448
+00:32:17,930 --> 00:32:21,150
+إحنا ممكن نلاقي الـ Antigen، نقيس الـ Antigen اللي
+
+449
+00:32:21,150 --> 00:32:26,630
+هو الـ Capsid بـ 24 Antigen، ممكن نقيسه عن طريق الـ
+
+450
+00:32:26,630 --> 00:32:31,430
+ELISA، الـ Antigen هذا ممكن نلاقي positive في
+
+451
+00:32:31,430 --> 00:32:34,530
+المرحلة الأولى من المرض قبل ما تبدأ تظهر الـ
+
+452
+00:32:34,530 --> 00:32:38,830
+Antibody، لكن بعد ما تظهر الـ Antibody، ممكن يختفي
+
+453
+00:32:38,830 --> 00:32:41,250
+الـ Antigen لأنه بيكون صار له neutralization مع
+
+454
+00:32:41,250 --> 00:32:47,170
+الـ Antibody، بس بعد فترة، لو زادت كمية الـ Antigen
+
+455
+00:32:47,170 --> 00:32:49,610
+عن كمية الـ Antibody في الـ Late Stage أو في الـ
+
+456
+00:32:49,610 --> 00:32:52,550
+Final Stage من الـ Infection، برضه ممكن يعطيني
+
+457
+00:32:52,550 --> 00:32:55,350
+Positive، إذا في المرحلة الأولى بيعطيني Positive
+
+458
+00:32:55,350 --> 00:32:58,410
+بعد هيك في الـ Latent Period لما بتتكون الـ
+
+459
+00:32:58,410 --> 00:33:01,450
+Antigen Antibody Complex، بيعطيني Negative بعد هيك
+
+460
+00:33:01,450 --> 00:33:03,750
+في الـ Late Stage، برضه بيعطيني Positive، الـ Virus
+
+461
+00:33:03,750 --> 00:33:06,970
+Isolation، طبعاً عارفين إحنا إن الـ Virus بتكاثر في
+
+462
+00:33:06,970 --> 00:33:11,150
+الـ T-Lymphocyte، فممكن نجيب Cell Line من الـ T
+
+463
+00:33:11,150 --> 00:33:16,080
+-Lymphoma ونزرع فيه الفيروس ونعمل viral isolation
+
+464
+00:33:16,080 --> 00:33:20,540
+طبعاً هي time-consuming ومزعجة وبتاخد أسابيع لغاية
+
+465
+00:33:20,540 --> 00:33:24,780
+ما أعزل الفيروس، ممكن أعمل demonstration للـ nucleic
+
+466
+00:33:24,780 --> 00:33:31,180
+acid للفيروس عن طريق الـ PCR، نيجي للـ HIV viral load
+
+467
+00:33:31,180 --> 00:33:34,040
+أني أعرف كمية الفيروس الموجودة عند هذا الشخص عن
+
+468
+00:33:34,040 --> 00:33:40,990
+طريق الـ real-time PCR، طبعاً يعني هذه بتلزمني غير
+
+469
+00:33:40,990 --> 00:33:43,310
+طبعاً إحنا في الـ Diagnosis بتلزمني بتحدد
+
+470
+00:33:43,310 --> 00:33:46,590
+الـ Virus، بتحدد كمية الـ Virus، بتلزم في متابعة
+
+471
+00:33:46,590 --> 00:33:51,030
+العلاج إذا الشخص بياخد Antiviral Chemotherapy، يعني
+
+472
+00:33:51,030 --> 00:33:55,830
+بتساعدني في معرفة مفعول العلاج أو تأثير العلاج
+
+473
+00:33:55,830 --> 00:34:00,670
+على هذا الشخص، شغل تانية إذا كان المريض الـ Viral
+
+474
+00:34:00,670 --> 00:34:03,920
+Load عنده قليل من البداية في فترة الـ Incubation
+
+475
+00:34:03,920 --> 00:34:07,140
+Period، بيكون الـ Prognosis لإله أفضل، نيجي للشغل
+
+476
+00:34:07,140 --> 00:34:10,580
+الأخيرة اللي هي الـ CD4 Count، أني أعد الخلايا اللي
+
+477
+00:34:10,580 --> 00:34:15,400
+هي CD4، هذه بتقسم الـ Immune Deficiency لتلت مراحل
+
+478
+00:34:15,400 --> 00:34:19,580
+إذا كان عددها أكثر من 500 خلية، بعتبر إنها Early
+
+479
+00:34:19,580 --> 00:34:23,560
+Immune Deficiency، إذا كان من 200 إلى 500 بعتبرها
+
+480
+00:34:23,560 --> 00:34:28,000
+Intermediate Immune Deficiency، إذا كان أقل من 200
+
+481
+00:34:28,000 --> 00:34:32,570
+بعتبرها Advanced Immune Deficiency، هيك إحنا بنكون
+
+482
+00:34:32,570 --> 00:34:36,210
+أخدنا الفحوصات اللي هامنا اللي بتلزم في تشخيص الـ
+
+483
+00:34:36,210 --> 00:34:40,650
+HIV، الـ Measurement of HIV Viral Load تخبرنا عن
+
+484
+00:34:40,650 --> 00:34:45,110
+مكان اتجاه المرض، و whereas CD4 Count تخبرنا عن
+
+485
+00:34:45,110 --> 00:34:49,330
+مكان اتجاه المرض في هذه اللحظة، يعني الـ HIV Viral
+
+486
+00:34:49,330 --> 00:34:53,590
+Load بقولي وين ايش مستقبل المرض، لكن الـ CD4 بتقولي
+
+487
+00:34:53,590 --> 00:34:56,970
+المرض وين واصل في هذه اللحظة، يعطيكم ألف عافية
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/Qdpgq8sG-To_postprocess.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/Qdpgq8sG-To_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..117c432f087b7ac461a9d9f228a7c56038f53e8e
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/Qdpgq8sG-To_postprocess.srt
@@ -0,0 +1,1948 @@
+1
+00:00:00,770 --> 00:00:04,370
+بسم الله الرحمن الرحيم اليوم إن شاء الله رب
+
+2
+00:00:04,370 --> 00:00:08,330
+العالمين راح يكون موضوعنا الـ Viral Hepatitis راح
+
+3
+00:00:08,330 --> 00:00:11,430
+ناخد الـ Serology of Viral Hepatitis و الـ
+
+4
+00:00:11,430 --> 00:00:15,990
+Hepatitis Markers و كيف بيتم تقييم الحالة و معرفة
+
+5
+00:00:15,990 --> 00:00:18,250
+الـ Stage بتاعة المرض إذا كان موجود أحنا عارفين
+
+6
+00:00:18,250 --> 00:00:24,530
+الـ Viral Hepatitis بيسببه فيروس بينتمي إلى أحد
+
+7
+00:00:24,530 --> 00:00:28,490
+هذه الفيروسات أكثر ثلاث أنواع شيوعاً اللي هو الـ
+
+8
+00:00:28,490 --> 00:00:33,240
+Hepatitis A Virusوالـ B فيروس والـ C فيروس لأن
+
+9
+00:00:33,240 --> 00:00:36,220
+نوعين الآخرين مش كتير شائعين اللي هما الـ
+
+10
+00:00:36,220 --> 00:00:41,480
+Hepatitis D والـ Hepatitis E فيروس الـ Hepatitis A
+
+11
+00:00:41,480 --> 00:00:47,000
+فيروس عبارة عن RNA فيروس هما كلهم RNA فيروس مع ده
+
+12
+00:00:47,000 --> 00:00:52,360
+Hepatitis B عبارة عن DNA فيروس كلهم RNA فيروس مع
+
+13
+00:00:52,360 --> 00:00:54,800
+ده Hepatitis B يعني الآن ليش احنا بنعمل فحص الـ
+
+14
+00:00:54,800 --> 00:01:00,830
+Hepatitis في مجموعة أسباب السبب الأولإذا كان الشخص
+
+15
+00:01:00,830 --> 00:01:05,030
+مصاب بـ Viral Hepatitis بدي أعرف إيش نوعه A أو B
+
+16
+00:01:05,030 --> 00:01:08,730
+أو C لأنه كل نوع من هذه الأنواع لها طريقة في
+
+17
+00:01:08,730 --> 00:01:13,690
+التعامل والعلاج الشغلة التانية ممكن نعمل Screen
+
+18
+00:01:13,690 --> 00:01:18,030
+للناس اللي بيشتغلوا بالمجال الطبي لأنهم في high
+
+19
+00:01:18,030 --> 00:01:22,830
+risk للإصابة فممكن نعمللهم الفحص من باب الإطمئنان
+
+20
+00:01:22,830 --> 00:01:25,810
+عليهم زي الأطباء والممرضين أو أطباء الأسنان
+
+21
+00:01:25,810 --> 00:01:32,530
+بنعمللهم هذا الفحص كscreenالشغلة التالتة الآن في
+
+22
+00:01:32,530 --> 00:01:37,130
+بنك الدم أي وحدة الدم قبل ما تنتقل من المريض لازم
+
+23
+00:01:37,130 --> 00:01:40,110
+نكون شريكنا على الـ Hepatitis و الـ HIV كمان فيها
+
+24
+00:01:40,110 --> 00:01:43,350
+لأنه زي ما أنتوا عارفين هي Blood Born Diseases
+
+25
+00:01:43,350 --> 00:01:46,730
+أمراض بتعيش في الدم و بتنتقل عن طريق الـ Blood
+
+26
+00:01:46,730 --> 00:01:50,430
+Transfusion فإحنا ما بدنا ننقل المرض وإنما بدنا
+
+27
+00:01:50,430 --> 00:01:57,010
+نمنع انتشاره طيب الشغلة الرابعة الآن Hepatitis B
+
+28
+00:01:57,010 --> 00:02:02,230
+مثلا صار له Vaccineفالآن بعد ما يتطعم الشخص بالـ
+
+29
+00:02:02,230 --> 00:02:07,050
+«هيبوتايتس B» ممكن أنا هو طبيعي هيتكون عنده
+
+30
+00:02:07,050 --> 00:02:10,790
+antibodies فأنا ممكن أشيك عليه هل فعلًا كون
+
+31
+00:02:10,790 --> 00:02:14,870
+antibodies وهل الـ antibodies هذي protective يعني
+
+32
+00:02:14,870 --> 00:02:18,070
+لأنه كل .. يعني ممكن كل واحد يكون antibodies لكن
+
+33
+00:02:18,070 --> 00:02:20,710
+مش شرط أنه تكون ال antibodies اللي اتطورت عند هذا
+
+34
+00:02:20,710 --> 00:02:23,030
+الشخص وصلت لـ level أنه تعمله protection من
+
+35
+00:02:23,030 --> 00:02:28,430
+الإصابة تعمله حماية من العدوىفاحنا ممكن نشوف الناس
+
+36
+00:02:28,430 --> 00:02:31,610
+اللي أخدت الـ Hepatitis Vaccine هل كوّنت
+
+37
+00:02:31,610 --> 00:02:38,170
+Antibodies بالشكل الكافي ولا لأ طيب نلاحظ طبعا
+
+38
+00:02:38,170 --> 00:02:40,730
+find out if a hepatitis virus infection is the
+
+39
+00:02:40,730 --> 00:02:43,510
+cause of abnormal liver function test يعني واحد
+
+40
+00:02:43,510 --> 00:02:47,350
+عنده أعراض مشاكل في الـ liver عنده abnormal liver
+
+41
+00:02:47,350 --> 00:02:50,670
+function testطب نعمل فخوصات الـ Viral Hepatitis
+
+42
+00:02:50,670 --> 00:02:53,910
+عشان نشوف هل الـ Viral Hepatitis هو السبب نيجي
+
+43
+00:02:53,910 --> 00:03:00,250
+بداية الـ Hepatitis A Virus أول
+
+44
+00:03:00,250 --> 00:03:05,210
+حاجة هي طبعا نيجي لخصائص Hepatitis A Virus طبعا هو
+
+45
+00:03:05,210 --> 00:03:09,910
+النوع الأكثر شيوعا اللي بصيب الأطفال عبارة عن زي
+
+46
+00:03:09,910 --> 00:03:14,570
+ما قلنا RNA Virus الـ Incubation Period لإله قصيرة
+
+47
+00:03:14,570 --> 00:03:19,940
+من أسبوعين إلى ست أسبوعميجي إلى الـ Mode of
+
+48
+00:03:19,940 --> 00:03:24,680
+Transmission كيف بينتقل الفيروس هذا الفيروس مختلف
+
+49
+00:03:24,680 --> 00:03:29,440
+عن الـ B والـ C في أنه بينتقل Fecal Oral Route
+
+50
+00:03:29,440 --> 00:03:33,380
+ممكن ينتقل من إنسان لإنسان عن طريق الـ
+
+51
+00:03:33,380 --> 00:03:36,260
+Contaminated Food أو الـ Water عن طريق الـ Direct
+
+52
+00:03:36,260 --> 00:03:42,440
+Contact مع إنسان مصاب الفيروس هذا بيظهر احنا قلنا
+
+53
+00:03:42,440 --> 00:03:46,200
+الـ Incubation Period من أسبوعين إلى ست أسابيعالآن
+
+54
+00:03:46,200 --> 00:03:52,240
+بيبدأ الفيروس يظهر في الـ stool بعد أسبوعين من الـ
+
+55
+00:03:52,240 --> 00:03:56,320
+infection حتى بدون ما تظهر الأعراض ففي هذه الفترة
+
+56
+00:03:56,320 --> 00:03:59,620
+بيبقى الشخص Infected بدون ما تظهر عليه أعراض وهي
+
+57
+00:03:59,620 --> 00:04:08,390
+مشكلته يعني الفيروس ممكن يصيب أكتر من نفسفي نفس
+
+58
+00:04:08,390 --> 00:04:11,730
+البيت وبعدين تبدأ تظهر الأعراض يوم ما تظهر الأعراض
+
+59
+00:04:11,730 --> 00:04:16,730
+انت سهل تعزل الإنسان المصاب وتحجريه لكن المشكلة في
+
+60
+00:04:16,730 --> 00:04:19,130
+الفترة اللي قبل هي فترة الـincubation period اللي
+
+61
+00:04:19,130 --> 00:04:23,510
+بيكون فيها الفيروس معدي طبعا أكثر الناس عرضة هم
+
+62
+00:04:23,510 --> 00:04:27,370
+الأطفال وغالبا كل ما كان السن أصغر كل ما كانت
+
+63
+00:04:27,370 --> 00:04:30,930
+الأعراض أقل حدة يعني لو أصابر كبار هذا بيكون متأكد
+
+64
+00:04:30,930 --> 00:04:34,670
+طيب الـinfective dose لهذا الفيروس قليلة بمعنى إنه
+
+65
+00:04:34,670 --> 00:04:37,370
+كمية بسيطة من الفيروس ممكن تعمل ال infection
+
+66
+00:04:38,350 --> 00:04:42,790
+ملاحظات أخرى على الفيروس أنه نادر أو غالباً ما
+
+67
+00:04:42,790 --> 00:04:45,350
+بينتقل عن طريق الـ blood بينتقل عن طريق زي ما
+
+68
+00:04:45,350 --> 00:04:49,690
+قلتلكم فيك الـ oral route ما بيصير chronic لأنه
+
+69
+00:04:49,690 --> 00:04:55,470
+عادة بتيجي ال infection بتظهر الأعراض acute بعد
+
+70
+00:04:55,470 --> 00:04:59,970
+هيك بتعافى المريض لحاله acute there is no chronic
+
+71
+00:04:59,970 --> 00:05:02,810
+career state of care يعني مافيش عندي واحد career
+
+72
+00:05:02,810 --> 00:05:06,630
+أقول إنه هذا career للمرض وبيعدي وممكن يعمل مشاكل،
+
+73
+00:05:06,630 --> 00:05:11,540
+لأهو أعراض وبتنتهي مع انتهاء الأعراض بيكون الفيروس
+
+74
+00:05:11,540 --> 00:05:17,820
+تقريبا انتهى شغلة تانية الأنواع التانية من الفيروس
+
+75
+00:05:17,820 --> 00:05:21,920
+الـ B و الـ C ممكن تكون يعني مسببة للـ
+
+76
+00:05:21,920 --> 00:05:26,040
+Hepatocellular Carcinoma لكن هذا لأ يعني غالبا ما
+
+77
+00:05:26,040 --> 00:05:28,900
+بيعملش أعراض خطيرة أو ما بيكونش مسبب للـ
+
+78
+00:05:28,900 --> 00:05:33,180
+Hepatocellular Carcinoma على المدى الطويل طيب هنا
+
+79
+00:05:33,180 --> 00:05:37,800
+في ملاحظة مهمةالفيروس هذا لو أصيب فيه الإنسان مرة
+
+80
+00:05:37,800 --> 00:05:42,380
+يعني لا يشترط إنه يأخذ Protection طول الحياة ممكن
+
+81
+00:05:42,380 --> 00:05:46,640
+يصاب فيه مرة أخرى الـ IGG تبعته ما بتظل طول الحياة
+
+82
+00:05:46,640 --> 00:05:50,220
+مهم جدا الـ Personal Hygiene الـ Hand Washing
+
+83
+00:05:50,220 --> 00:05:55,760
+والأشياء هذه عشان نحد من انتقاله للناس الـ Signs
+
+84
+00:05:55,760 --> 00:06:01,180
+تاعة الـ Hepatitis تقريبا يعني مشتركة Abdominal
+
+85
+00:06:01,180 --> 00:06:05,560
+painبيصير jaundice صفار شديد في الإينان وفي الجلد
+
+86
+00:06:05,560 --> 00:06:12,120
+nausea or vomiting بيصير weight loss itch skin
+
+87
+00:06:12,120 --> 00:06:15,300
+نتيجة وجود الفيروس في الـ في الـ blood بيعمل حكة
+
+88
+00:06:15,300 --> 00:06:21,440
+شديدة بيعمل انتفاخ في الـ abdomen طيب
+
+89
+00:06:21,440 --> 00:06:24,430
+نيجي لل lab diagnosisغالباً إيه بنات ال lab
+
+90
+00:06:24,430 --> 00:06:27,670
+diagnosis يعني هو إذا طفل ظهرت عليه أعراض الصفار
+
+91
+00:06:27,670 --> 00:06:31,690
+بيعملوله فحص ال urine ال urine عادة هنلاقي فيه ال
+
+92
+00:06:31,690 --> 00:06:34,890
+bilirubin عالي إذا لاقينا ال bilirubin عالي ممكن
+
+93
+00:06:34,890 --> 00:06:38,230
+الدكتور يطلبله liver enzymes وخلاص بيتأكد إنه مريض
+
+94
+00:06:38,230 --> 00:06:43,930
+hepatitis A وبالطفل يعني بتحمى عن أشياء معينة
+
+95
+00:06:43,930 --> 00:06:48,030
+بيقولوله يعني ابعد عن الأشياء اللي فيها دهون خليك
+
+96
+00:06:48,030 --> 00:06:51,070
+على الأشياء اللي فيها السكريات على أساس إنه يعني
+
+97
+00:06:51,070 --> 00:06:55,660
+ما نرهقش ال liverالبروتينات برضه مهمة، البروتينات
+
+98
+00:06:55,660 --> 00:06:59,500
+بدون دهون عشان يكوّن أجسام مضادة ويتكلب على المرض
+
+99
+00:06:59,500 --> 00:07:03,840
+فبالتالي يعني من خلال فحصات ال chemistry عند
+
+100
+00:07:03,840 --> 00:07:07,260
+الأطفال من ال urine والchemistry بتتم تشخصه، تمام؟
+
+101
+00:07:07,260 --> 00:07:11,140
+لكن لو أصاب ال adult، يعني هنا بيصير هل هو B ولا A
+
+102
+00:07:11,140 --> 00:07:15,720
+فممكن نلجأ لإنه نحدد ال antibodies ذاته عشان نعرف
+
+103
+00:07:15,720 --> 00:07:19,520
+إذا كان مثلا Hepatitis A و لا Hepatitis B و لا
+
+104
+00:07:19,520 --> 00:07:24,520
+Hepatitis C مثلافممكن ينعملوا زي الـ RIA أو الـ
+
+105
+00:07:24,520 --> 00:07:29,620
+ELISA عشان يحدد الـ IgM خلال أسبوعين أو تلت أسابيع
+
+106
+00:07:29,620 --> 00:07:35,020
+من الـ infection وبعد فترة ممكن نعمل فحص الـ IgG
+
+107
+00:07:35,020 --> 00:07:39,420
+في فحص بيسمون Rapid Assay غير الـ ELISA اللي هو
+
+108
+00:07:39,420 --> 00:07:45,500
+الـ Strip هذا اللي حكينا عنه أو هناخدهالـ Strip
+
+109
+00:07:45,500 --> 00:07:48,980
+هذا بتحط الـ Drop شبه فحص الحمل فبطلع معاكي إذا
+
+110
+00:07:48,980 --> 00:07:51,700
+كانت النتيجة بطلع معاكي خطين إذا كانت positive
+
+111
+00:07:51,700 --> 00:07:57,120
+فبطلع معاكي خط واحد إذا كانت negative تمام هذا
+
+112
+00:07:57,120 --> 00:08:01,640
+بيسموه ال Rapid Assay لأنه فحص سريع وبسرعة بيعطيني
+
+113
+00:08:01,640 --> 00:08:05,320
+نتيجةممكن نعمل detection للفيروس في الـ feces عن
+
+114
+00:08:05,320 --> 00:08:08,940
+طريق الـ electron microscope ممكن نعزل الفيروس
+
+115
+00:08:08,940 --> 00:08:12,320
+يعني أنا قلت الطريقتين هدول لأنهم يعني بكلفهم مش
+
+116
+00:08:12,320 --> 00:08:14,920
+دايما متاحين يعني في ال clinical laboratory أنه
+
+117
+00:08:14,920 --> 00:08:20,260
+نعزله بـ cell culture و نعمل diagnosis لإله، تمام؟
+
+118
+00:08:20,260 --> 00:08:27,680
+نيجي للـ Hepatitis B virus الـ Hepatitis B virus
+
+119
+00:08:27,680 --> 00:08:33,340
+عبارة عن DNA virusفي منه شكلان في منه اللي هو
+
+120
+00:08:33,340 --> 00:08:38,080
+spherical particles وفي عندي filamentous particles
+
+121
+00:08:38,080 --> 00:08:41,880
+ال incubation period هاخدوا بالكم هناك قلنا أسابيع
+
+122
+00:08:41,880 --> 00:08:46,200
+هنا من شهرين إلى ست شهور من خمسين إلى مية و تمانين
+
+123
+00:08:46,200 --> 00:08:46,520
+يوم
+
+124
+00:08:49,620 --> 00:08:54,140
+طريقة الـ Transmission طبعاً خلال الولادة Vertical
+
+125
+00:08:54,140 --> 00:08:58,000
+Transmission من الـ mother للbaby ممكن Sexual
+
+126
+00:08:58,000 --> 00:09:02,180
+Transmission عن طريق الـ Blood Transfusion Sharing
+
+127
+00:09:02,180 --> 00:09:07,200
+Contaminated Needles or Other Equipment Parental
+
+128
+00:09:07,200 --> 00:09:09,940
+Transmission اللي هو عن طريق الأدوات هذه تخريم
+
+129
+00:09:09,940 --> 00:09:13,240
+الودن أو التتو أو الأشياء اللي مثلها ممكن لو كانتش
+
+130
+00:09:13,240 --> 00:09:16,440
+الأدوات معقمة ينتقل عن طريقها
+
+131
+00:09:19,270 --> 00:09:23,510
+الـ Symptoms تقريبًا نفس الـ Symptoms بتاعت A بس
+
+132
+00:09:23,510 --> 00:09:26,450
+هذه مشكلتها إنها بتكون أشد و بتطول يعني بتقعد فترة
+
+133
+00:09:26,450 --> 00:09:30,490
+أطول Sharp, Mild, Flu-like illness, Nausea,
+
+134
+00:09:30,570 --> 00:09:32,930
+Fatigue, Abdominal pain, Weight loss, Joints,
+
+135
+00:09:33,210 --> 00:09:40,990
+Itchy skin الآن
+
+136
+00:09:40,990 --> 00:09:44,790
+بقولك إذا الشخص يعني ضال معاه Hepatitis B لعدة
+
+137
+00:09:44,790 --> 00:09:49,180
+سنوات ممكن يصير عنده أحد الـ Complication هذهممكن
+
+138
+00:09:49,180 --> 00:09:53,720
+يتحول لـ Chronic تمام، ممكن يصير عنده liver
+
+139
+00:09:53,720 --> 00:09:57,960
+cirrhosis ممكن يتحول ل .. يعني ممكن يكون مسبب للـ
+
+140
+00:09:57,960 --> 00:10:00,640
+hepatocellular carcinoma ممكن يتحول لـ liver
+
+141
+00:10:00,640 --> 00:10:05,900
+cancer هنا حاططلك بس صورة للـ Healthy liver بعد
+
+142
+00:10:05,900 --> 00:10:11,120
+هيك المرحلة الأولى يعني تبدأ بداية تلايف بسيط
+
+143
+00:10:11,120 --> 00:10:16,410
+للكبدمن ال inflammation فببدأ يصير fibrosis في ال
+
+144
+00:10:16,410 --> 00:10:20,290
+liver بعد هيك بيصير cirrhosis لل liver طبعا اللي
+
+145
+00:10:20,290 --> 00:10:25,570
+بتلاقي معظم ال liver استبدلت بخلايا ميتة فبالتالي
+
+146
+00:10:25,570 --> 00:10:29,010
+بتقل الوظيفة بتاعتها بشكل كتير كبير بعد هيك ممكن
+
+147
+00:10:29,010 --> 00:10:36,590
+يصير liver cancer نيجي
+
+148
+00:10:36,590 --> 00:10:40,120
+لل lab diagnosisالـ Lab Diagnosis أول حاجة ممكن
+
+149
+00:10:40,120 --> 00:10:43,460
+نعمل فحوصات الـ Chemistry اللي هي liver function
+
+150
+00:10:43,460 --> 00:10:49,360
+tests ممكن طبعاً بتكون مرتفعة liver function tests
+
+151
+00:10:49,360 --> 00:10:53,620
+كلياتها ممكن ندور على الـ hepatitis B surface
+
+152
+00:10:53,620 --> 00:10:57,340
+antigen إذا الـ hepatitis B surface antigen موجود
+
+153
+00:10:57,340 --> 00:11:00,960
+بأكد الـ diagnosis ممكن نختبره عن طريق الـ ELISA
+
+154
+00:11:00,960 --> 00:11:05,750
+أو الـ RIAفي عندنا الـ Serological Testing هنحكي
+
+155
+00:11:05,750 --> 00:11:08,750
+عنها يعني إلنا فيها كلام كتير اللي هي نعرف الـ
+
+156
+00:11:08,750 --> 00:11:11,930
+Hepatitis Marker هاد الـ Serological Testing بوضّح
+
+157
+00:11:11,930 --> 00:11:17,110
+عندي المريض في أي مرحلة من مراحل المرض ممكن نحدد
+
+158
+00:11:17,110 --> 00:11:22,570
+الـ Viral DNA Load باستخدام فخصات الـ PCR ممكن
+
+159
+00:11:22,570 --> 00:11:29,190
+نعمل Liver Biopsy وPCR من الـ Liver نفسها طيب،
+
+160
+00:11:29,190 --> 00:11:32,570
+نحكي عن الـ Hepatitis Markersهد ايش الفايدة منها
+
+161
+00:11:32,570 --> 00:11:35,930
+الـ Hepatitis Markers بتقوللي أو بتخبرني إيش وضع
+
+162
+00:11:35,930 --> 00:11:39,210
+المرض عند هذا الشخص عند هذا المريض يعني هل هو
+
+163
+00:11:39,210 --> 00:11:43,570
+acute هل هو مريض chronic هل هو معدي مش معدي and so
+
+164
+00:11:43,570 --> 00:11:49,270
+on تمام أول واحد الـ Hepatitis B Surface Antigen
+
+165
+00:11:49,270 --> 00:11:55,830
+هذا عبارة عن أنتجن موجود على الـ Surface بتاع
+
+166
+00:11:55,830 --> 00:12:02,420
+الفيروس تمام بيظهرمن شهرين إلى ست شهور بعد الـ
+
+167
+00:12:02,420 --> 00:12:06,540
+infection إذا كان موجود و positive معنى الكلام إن
+
+168
+00:12:06,540 --> 00:12:10,080
+الشخص هذا الـ virus موجود عنده إما acute أو
+
+169
+00:12:10,080 --> 00:12:13,820
+chronic طيب،
+
+170
+00:12:13,820 --> 00:12:17,880
+هلاقيت الـ surface antigen هيتكون له antibody
+
+171
+00:12:17,880 --> 00:12:25,600
+هيبدأ الجسم يكون له antibody إذا ارتفع الـ surface
+
+172
+00:12:25,600 --> 00:12:30,600
+antibodyوصار الـ Antigen Negative معنى الكلام إنه
+
+173
+00:12:30,600 --> 00:12:34,520
+هذا الشخص شفي تماما تعافى يعني الفيروس مش موجود
+
+174
+00:12:34,520 --> 00:12:37,300
+عنده ولا chronic ولا حاجة انتهى الفيروس من عنده
+
+175
+00:12:37,300 --> 00:12:42,100
+إذا الشرط إنه ينتهي الفيروس إنه يكون الـ Hepatitis
+
+176
+00:12:42,100 --> 00:12:48,560
+B surface antigen negative إذا كان positive معنى
+
+177
+00:12:48,560 --> 00:12:51,800
+الكلام إن الشخص هذا إما acute infection أو chronic
+
+178
+00:12:51,800 --> 00:12:54,820
+يعني الفيروس موجود عنده طيب، ليه يشيل الـ
+
+179
+00:12:54,820 --> 00:12:58,040
+Hepatitis B surface antibody؟Hepatitis B Surface
+
+180
+00:12:58,040 --> 00:13:02,040
+Antibody هذا عبارة عن Antibody بتتوين للـ Surface
+
+181
+00:13:02,040 --> 00:13:05,800
+Antigen عشان يكسره، يعمله تكسير وزي ما قلنا إذا
+
+182
+00:13:05,800 --> 00:13:09,020
+ارتفع الـ Surface Antibody معنى الكلام إن الشخص
+
+183
+00:13:09,020 --> 00:13:13,980
+شفي تماما من الفيروس وفي هذه اللحظة لما هذا يرتفع
+
+184
+00:13:13,980 --> 00:13:15,980
+الـ Antibody الـ Antigen الـ Surface Antigen
+
+185
+00:13:15,980 --> 00:13:20,960
+حينتهي يعني اتنينها Dolphinيعني الـ Antibody بتكون
+
+186
+00:13:20,960 --> 00:13:24,400
+Against الـ Surface Antigen إذا ارتفع الـ Antibody
+
+187
+00:13:24,400 --> 00:13:28,460
+بيقضي على الـ Antigen ويكون الشخص شفي تماماً طيب،
+
+188
+00:13:28,460 --> 00:13:31,940
+لو لاقيت الـ Hepatitis B Surface Antibody Positive
+
+189
+00:13:31,940 --> 00:13:35,400
+هذا بيدل على واحدة من التلتانية إما إن الشخص أصيبه
+
+190
+00:13:35,400 --> 00:13:39,220
+شفي أو إنه أخد Vaccine لأن الـ Vaccine تعي الـ
+
+191
+00:13:39,220 --> 00:13:42,820
+Hepatitis عبارة عن Surface Antigen الـ Vaccine تعي
+
+192
+00:13:42,820 --> 00:13:44,960
+الـ Hepatitis عبارة عن Surface Antigen فإذا الشخص
+
+193
+00:13:44,960 --> 00:13:48,500
+أخد الـ Vaccine هتلاقي حيرتف عنده Surface Antibody
+
+194
+00:13:48,780 --> 00:13:53,020
+تمام؟ خلصنا من هدول الاتنين نيجي للتالت Hepatitis
+
+195
+00:13:53,020 --> 00:13:56,900
+B Core Antibody هذا عبارة عن Antibody بتكون للـ
+
+196
+00:13:56,900 --> 00:14:03,060
+Core بتاع الـ B Virus Hepatitis B Virus هذا بيبدأ
+
+197
+00:14:03,060 --> 00:14:08,940
+يرتفع بغض النظر الإصابة acute، chronic، انتهى
+
+198
+00:14:08,940 --> 00:14:13,640
+الفيروس ما انتهاش، هتلاقي مرتفع طيب، إيش الفرق بين
+
+199
+00:14:13,640 --> 00:14:17,420
+الـ Core Antibody والـ Surface Antibody؟الـ Core
+
+200
+00:14:17,420 --> 00:14:20,100
+Antibody إذا ارتفع لا يدل على إن الـ infection
+
+201
+00:14:20,100 --> 00:14:24,720
+انتهت بينما الـ Surface Antibody إذا ارتفع معناة
+
+202
+00:14:24,720 --> 00:14:28,140
+كلام إن ال infection خلصت والشخص شفي تماما يعني
+
+203
+00:14:28,140 --> 00:14:31,600
+ارتفاع الـ Core Antibody قد يكون على إنه قد يدل
+
+204
+00:14:31,600 --> 00:14:34,720
+على إنه acute infection أو chronic infection أو
+
+205
+00:14:34,720 --> 00:14:38,920
+حتى لو الشخص شفي أو طاب برضه هتلاقي مرتفعيعني هو
+
+206
+00:14:38,920 --> 00:14:43,060
+بيقوللي اتفاعه إن الفيروس مر من هنا الفيروس دخل
+
+207
+00:14:43,060 --> 00:14:46,620
+الجسم، بغرد ما يدخل الفيروس الجسم هذا هيعطي علامة
+
+208
+00:14:46,620 --> 00:14:51,380
+طول العمر ويكون positive تمام؟ يجي للـ Hepatitis B
+
+209
+00:14:51,380 --> 00:14:55,160
+E-Antigen هذا الـ marker الرابع هذا الـ Antigen
+
+210
+00:14:55,160 --> 00:14:58,320
+موجود في الـ original أو الـ wild type من الفيروس
+
+211
+00:14:58,320 --> 00:15:04,560
+هذا الـ Antigen بدل على نشاط الفيروس يعني هل
+
+212
+00:15:04,560 --> 00:15:09,910
+الفيروس نشيطوقادر على إنه يتكاثر وبالتالي شرسته
+
+213
+00:15:09,910 --> 00:15:16,150
+وضراوته بتكون أكتر ولا لأ؟ إذا كان هذا موجود بيدل
+
+214
+00:15:16,150 --> 00:15:19,930
+على إن الـ Virus is actively replicated يعني هو
+
+215
+00:15:19,930 --> 00:15:24,510
+يتكاثر بسرعة ومش
+
+216
+00:15:24,510 --> 00:15:27,130
+طايرله Control لسه لغاية الآن مش طايرله Control
+
+217
+00:15:27,130 --> 00:15:34,320
+طبعاً ممكن يتكون Antibody للـ E-Antigenتمام؟ فلقيت
+
+218
+00:15:34,320 --> 00:15:39,420
+إذا اتكون الـ E-antibody هذا هيوقف الـ E-antigen
+
+219
+00:15:39,420 --> 00:15:45,360
+لكن لا يقضي على الفيروس هو لا يقضي على الفيروس لكن
+
+220
+00:15:45,360 --> 00:15:49,700
+يوقف نشاطه بمعنى إذا لقيت الـ Anti-hepatitis E
+
+221
+00:15:49,700 --> 00:15:55,920
+مرتفع والـ hepatitis E antigen راح انخفض هذه
+
+222
+00:15:55,920 --> 00:16:00,680
+بيسموها Seroconversionهذا not a cure، لا يُعتبر
+
+223
+00:16:00,680 --> 00:16:06,300
+شفاء وإنما يُعتبر أو يدل على إن الفيروس صار له
+
+224
+00:16:06,300 --> 00:16:09,940
+control عن طريق الـ Immune System لكن لازال
+
+225
+00:16:09,940 --> 00:16:14,240
+الفيروس موجود وممكن يظل سنوات طويلة الفيروس بهذا
+
+226
+00:16:14,240 --> 00:16:20,760
+الوضع إن الـ Hepatitis B Antibody موجود ومرتفع
+
+227
+00:16:20,760 --> 00:16:25,360
+وموقف نشاط الفيروس عيار هذا انخفض، هتلاقي إن
+
+228
+00:16:25,360 --> 00:16:32,190
+الفيروس ممكن يرجع يتنشطتمام يا بنات؟ إذا إيش فيه
+
+229
+00:16:32,190 --> 00:16:37,190
+هنا؟ زي ما قلنا إن انخفاض الانتجن أو إن الانتجن
+
+230
+00:16:37,190 --> 00:16:41,010
+هذا راح لا يعني إنه شفاء but this virus is being
+
+231
+00:16:41,010 --> 00:16:43,310
+controlled by the immune system and cannot
+
+232
+00:16:43,310 --> 00:16:50,230
+replicate well anymore مش هيتكاتر بشكل أكبر وهذا
+
+233
+00:16:50,230 --> 00:16:56,350
+نفس الكلام هيتكرر عن الانتجنهنا عندك هذا الـ Curve
+
+234
+00:16:56,350 --> 00:16:59,710
+بيبين الـ Hepatitis Markers وارتفاعها كل واحد في
+
+235
+00:16:59,710 --> 00:17:04,390
+أي مرحلة ممكن يرتفع بداية الـ Hepatitis B Surface
+
+236
+00:17:04,390 --> 00:17:09,050
+Antigen بيبدأ يرتفع تمام؟ بدنا ناخد الـ Antigen و
+
+237
+00:17:09,050 --> 00:17:12,450
+الـ Antibody بتاعه و نشوف إيش بيصير هلقيت؟ وين الـ
+
+238
+00:17:12,450 --> 00:17:17,130
+Hepatitis B Surface Antibody هيه؟ هذا اللي لونه
+
+239
+00:17:17,130 --> 00:17:23,330
+كحلي اللي هو الـ Hepatitis B Antibody كويس؟ هلقيت؟
+
+240
+00:17:23,570 --> 00:17:27,270
+لما برتفع الـ Antibody، الـ Antigen حينتهي وهذه
+
+241
+00:17:27,270 --> 00:17:33,050
+بعتبرها مرحلة أش مرحلة الشفاء التام مرحلة أش،
+
+242
+00:17:33,050 --> 00:17:36,950
+مرحلة الشفاء التام إن الـ Surface Antigen انتهى
+
+243
+00:17:36,950 --> 00:17:41,290
+وارتفع الـ Surface Antibody وحيظل مرتفع على طول
+
+244
+00:17:41,290 --> 00:17:46,910
+طيب، نيجي للـ E-Antigen نفس الأشي، الـ Antigen نزل
+
+245
+00:17:46,910 --> 00:17:51,710
+وهيرتفع عندي الـ Antibodyطبعاً هذه مش مرحلة شفاء
+
+246
+00:17:51,710 --> 00:17:55,930
+مرحلة control للفيروس اللي بيهمني أكتر عشان أحدد
+
+247
+00:17:55,930 --> 00:17:59,730
+إن الشخص فعلا شفي و لا لأ الـ Hepatitis B Surface
+
+248
+00:17:59,730 --> 00:18:02,990
+Antigen هذا هو اللي بدل على إن الفيروس انتهى و لا
+
+249
+00:18:02,990 --> 00:18:08,190
+لأ طيب بعد هتبيجي عندي الـ Core الـ Core في بداية
+
+250
+00:18:08,190 --> 00:18:13,970
+الـ Anticore Antibody Hepatitis B أول إشي هيرتفع
+
+251
+00:18:13,970 --> 00:18:20,990
+عندي الـ IgM تمام؟ هيرتفع عندي الـ IgMوهيبدأ ينزل
+
+252
+00:18:20,990 --> 00:18:26,570
+وطبعاً هيرتفع عندي بعد هيك الـ IgG لو انتوا لاحظته
+
+253
+00:18:26,570 --> 00:18:30,270
+هذا الخط الغامق اللي فوق هذا بشكل الـ IgM مع الـ
+
+254
+00:18:30,270 --> 00:18:34,410
+IgG يعني هو ما فصل هو اعتبر Total IgM و IgG
+
+255
+00:18:34,410 --> 00:18:38,370
+فبالتالي مع بداية الارتفاع هيرتفعه هينزل الـ IgM
+
+256
+00:18:38,370 --> 00:18:42,950
+بس الـ IgG هيظل مرتفع على طول إذا في النهاية بتوقع
+
+257
+00:18:42,950 --> 00:18:48,190
+يكون الـ Core أي شخص دخل جسمه الفيروسهيكون الـ
+
+258
+00:18:48,190 --> 00:18:53,630
+Core Antibody Positive أي واحد الطعم أو دخل جسمه
+
+259
+00:18:53,630 --> 00:18:57,850
+الفيروس هيكون الـ Antibiotitis B Surface Positive
+
+260
+00:18:57,850 --> 00:19:02,010
+لما يكون الـ Antibiotitis E Positive معنى الكلام
+
+261
+00:19:02,010 --> 00:19:08,090
+إنه الفيروس Under Control هذه الفترات الزمنية
+
+262
+00:19:08,090 --> 00:19:13,930
+المتوقعة لارتفاع الـ Antibodies طيب،
+
+263
+00:19:13,930 --> 00:19:18,180
+خلّيني نشوفالآن كل مرحلة من مراحل المرض مين بيكون
+
+264
+00:19:18,180 --> 00:19:22,020
+فيها Positive و Negative زي ملخص بشكل أبسط أول
+
+265
+00:19:22,020 --> 00:19:25,540
+حاجة مرحلة الـ Incubation Period إنه لسه ما فيه
+
+266
+00:19:25,540 --> 00:19:29,000
+أعراض هنلاقي على الأكيد Hepatitis B Surface
+
+267
+00:19:29,000 --> 00:19:32,120
+Antigen Positive إحنا قلنا بيبدأ يظهر من البدايات
+
+268
+00:19:32,120 --> 00:19:35,680
+يعني ممكن تلت أسابيع من بداية ال infection يبدأ
+
+269
+00:19:35,680 --> 00:19:39,720
+يعطيني Positive بدون أعراض الـ E ممكن يكون
+
+270
+00:19:39,720 --> 00:19:43,410
+Positive أو Negative يعني مش كتير من القياسالمهم
+
+271
+00:19:43,410 --> 00:19:46,510
+الـ Surface Antigen هو الـ Positive طيب، في مرحلة
+
+272
+00:19:46,510 --> 00:19:50,490
+الـ Acute Hepatitis الـ Acute Hepatitis يعني
+
+273
+00:19:50,490 --> 00:19:55,850
+الفيروس موجود ونشط وبتكاثر فهتلاقي الـ Hepatitis
+
+274
+00:19:55,850 --> 00:19:59,770
+Surface Antigen Positive والـ Hepatitis E Antigen
+
+275
+00:19:59,770 --> 00:20:03,290
+Positive لكن الـ Antibodies بتاعتهم لسه ما اتكونت
+
+276
+00:20:03,290 --> 00:20:07,850
+لأنه لو اتكونت هيبدأ الفيروس يقل نشاطه، صح؟مين
+
+277
+00:20:07,850 --> 00:20:10,670
+اللي هيرتفع اللي هو الـ CAR اللي زي ما قلتلكم
+
+278
+00:20:10,670 --> 00:20:14,330
+هيعطي دمغة إنه الفيروس موجود في الـ Acute
+
+279
+00:20:14,330 --> 00:20:19,370
+Hepatitis هتلاقي الـ CAR IgM Positive وبعد هيك
+
+280
+00:20:19,370 --> 00:20:21,830
+طبعا الـ Total هيكون Positive لأنني قلتلكم الـ
+
+281
+00:20:21,830 --> 00:20:26,750
+Total بيشمل الـ IgM والـ IgG، تمام؟ طيب، نيجي
+
+282
+00:20:26,750 --> 00:20:33,270
+لاللي بعد هالمرحلة Chronic Carrier Career معنى
+
+283
+00:20:33,270 --> 00:20:37,630
+الكلامwith low infectivity خلّوا بالكم low
+
+284
+00:20:37,630 --> 00:20:42,130
+infectivity يعني مش معدي والفيروس مش نشط هنلاقي
+
+285
+00:20:42,130 --> 00:20:45,090
+career يعني الانتجين لازال موجود ال surface
+
+286
+00:20:45,090 --> 00:20:51,170
+antigen لازال موجود الفيروس موجود طبعاً
+
+287
+00:20:51,170 --> 00:20:55,850
+ماانتهاش الفيروس ليش؟ لأنه ال antibody لل surface
+
+288
+00:20:55,850 --> 00:21:01,030
+مرتفع لازال negative طالما ال hepatitis BSurface
+
+289
+00:21:01,030 --> 00:21:04,550
+Antibody Negative هيظل الفيروس موجود و هيكون الشخص
+
+290
+00:21:04,550 --> 00:21:09,170
+هذا career طيب ال career يا بنات في منه نوعين Low
+
+291
+00:21:09,170 --> 00:21:11,990
+Infectivity و High Infectivity طلعوا معايا
+
+292
+00:21:11,990 --> 00:21:15,610
+الحالتين هدول اللي فوق بعض، إيش بيفرقهم؟ التنتين
+
+293
+00:21:15,610 --> 00:21:18,570
+career يعني الـ Hepatitis B Surface Antigen موجود
+
+294
+00:21:18,570 --> 00:21:22,970
+فيهم، تمام؟ والتنتين الـ Hepatitis B Surface
+
+295
+00:21:22,970 --> 00:21:26,230
+Antibody مش موجود لأنه لو موجود هيبطل career و
+
+296
+00:21:26,230 --> 00:21:31,620
+هنعدي في مرحلة الشفاء، صح؟اللي بيفرقوا عن بعض الـ
+
+297
+00:21:31,620 --> 00:21:36,620
+Hepatitis E Early Antigen الـ Hepatitis، عفوا، الـ
+
+298
+00:21:36,620 --> 00:21:39,920
+E-Antigen هلقيت الـ E-Antigen في الـ Low
+
+299
+00:21:39,920 --> 00:21:44,420
+Infectivity Negative يعني هذا الشخص بيفرق عن هذا
+
+300
+00:21:44,420 --> 00:21:50,840
+إنه الفيروس في الحالة الأولى مش نشط وما بيتكاثر
+
+301
+00:21:50,840 --> 00:21:53,980
+لأن الـ E-Antigen Negative و الـ E-Antibody
+
+302
+00:21:53,980 --> 00:21:59,920
+Positive تمام؟بينما الحالة التانية الـ E-antigen
+
+303
+00:21:59,920 --> 00:22:04,980
+positive والـ E-antibody negative فبالتالي الشخص
+
+304
+00:22:04,980 --> 00:22:10,700
+هذا بيقول «highly infective» ليش؟ لأنه ما عنده E
+
+305
+00:22:10,700 --> 00:22:13,900
+-antibody التنين chronic والتنين عندهم الفيروس لكن
+
+306
+00:22:13,900 --> 00:22:17,720
+واحد في عندهم الفيروس نشط وبيتكثر وبيعدي وواحد لأ
+
+307
+00:22:18,680 --> 00:22:22,660
+بالنسبة للـ Core قلت لكم هيكون موجود بداية في الـ
+
+308
+00:22:22,660 --> 00:22:26,020
+Acute بيكون Positive الـ IgM بعد هيك بيظل عندى الـ
+
+309
+00:22:26,020 --> 00:22:28,520
+Total اللي هو زى ما قلت لكم الـ IgG هو اللي بيكون
+
+310
+00:22:28,520 --> 00:22:33,500
+Positive مرحلة الـ Convalescence مرحلة التعافى
+
+311
+00:22:33,500 --> 00:22:39,240
+هتلاقي كل إشي عنده Negative إن الشخص شفى ويعني بطل
+
+312
+00:22:39,240 --> 00:22:42,740
+طيب ليش الـ Antibodies هتلاقيها Negative؟ يعني هي
+
+313
+00:22:42,740 --> 00:22:48,550
+الآنفي عندي بداية تكوين للـ Antibody لكن لسه مش
+
+314
+00:22:48,550 --> 00:22:52,210
+ملموسة يعني انتهى الـ Antigen لكن لسه الـ Antibody
+
+315
+00:22:52,210 --> 00:22:55,650
+مش كتير detectable في الـ Blood بس مين اللي موجود
+
+316
+00:22:55,650 --> 00:23:01,530
+اللي هو الـ Car Past Infection يعني هذه مرحلة أول
+
+317
+00:23:01,530 --> 00:23:04,050
+ما بيبدأ الشخص يتعافى من المرض لسه الـ Antibodies
+
+318
+00:23:04,050 --> 00:23:07,370
+متكونش عالية ومميزة في الـ Serum اللي هو اللي
+
+319
+00:23:07,370 --> 00:23:12,630
+بتاتس بيه Surface Antibody بكونش واضحهلاقيت واحدة
+
+320
+00:23:12,630 --> 00:23:17,270
+اتعافى وخلاص تمام مافيش عنده مشكلة هتلاقي الـ
+
+321
+00:23:17,270 --> 00:23:21,150
+Surface Antibody ارتفع معنى الكلام أن هذا الشخص
+
+322
+00:23:21,150 --> 00:23:25,350
+اتعافى تماما وانتهى الـ Virus من عنده وبرضه هتلاقي
+
+323
+00:23:25,350 --> 00:23:28,470
+الـ Car Positive طيب واحد أخد الـ Vaccine مين
+
+324
+00:23:28,470 --> 00:23:34,330
+هلاقي عنده Positive؟
+
+325
+00:23:34,330 --> 00:23:38,610
+نيجي الآن للسؤال هل Hepatitis B Virus له تطعيم؟
+
+326
+00:23:38,610 --> 00:23:43,700
+صحيح Hepatitis B Virus له تطعيمطبعا التطعيم عبارة
+
+327
+00:23:43,700 --> 00:23:46,540
+عن Hepatitis B Surface Antigen بيحضروه بالـ
+
+328
+00:23:46,540 --> 00:23:50,360
+Recombinant DNA Technology تلان الأطفال يعني
+
+329
+00:23:50,360 --> 00:23:54,460
+متعامين بيتعاموا إلهم برنامج خاص لتطعيم الـ
+
+330
+00:23:54,460 --> 00:23:58,040
+Hepatitis ولو في واحد كبير من الأجيال اللي ما
+
+331
+00:23:58,040 --> 00:24:00,480
+اتعامت قبل هيك يفترض أن يدور على حاله وياخد
+
+332
+00:24:00,480 --> 00:24:07,090
+التطعيم من باب الوقايةعادة بعد التطعيم تأخذ عين
+
+333
+00:24:07,090 --> 00:24:09,790
+الدم عشان نشوف هل التطعيم شغل كويس وكوّن
+
+334
+00:24:09,790 --> 00:24:13,350
+antibodies وعطى حماية ولا لأ على الأقل التطعيم
+
+335
+00:24:13,350 --> 00:24:17,670
+بيعطي حماية أو بيظل الـ Titer للـ Antibody لمدة 5
+
+336
+00:24:17,670 --> 00:24:20,610
+سنين على الأقل وإن كان يعني بيعطي حماية لفترة أكبر
+
+337
+00:24:20,610 --> 00:24:25,090
+نقل الـ Hepatitis C Virus طبعاً هذا الـ Virus اللي
+
+338
+00:24:25,090 --> 00:24:28,750
+هو يعني مشكلته أنه مالاش تطعيم و أخطر من Hepatitis
+
+339
+00:24:28,750 --> 00:24:35,690
+B Hepatitis CIncubation period من 15 إلى 150 يوم
+
+340
+00:24:35,690 --> 00:24:42,130
+وعبارة عن RNA Virus أنيجي للـ Transmission of
+
+341
+00:24:42,130 --> 00:24:45,590
+Hepatitis C Virus بينتقل تقريبا بنفس الطرق اللي
+
+342
+00:24:45,590 --> 00:24:48,130
+بينتقل فيها Hepatitis B وإن كان الـ Sexual
+
+343
+00:24:48,130 --> 00:24:50,710
+Transmission و الـ Vertical Transmission من ال
+
+344
+00:24:50,710 --> 00:24:54,210
+mother لل baby و ال breast feeding أو ال breast
+
+345
+00:24:54,210 --> 00:24:59,870
+milk مش كتير مؤكد أنه بينتقل عن طريقهمالأن معظم
+
+346
+00:24:59,870 --> 00:25:02,730
+فيه يعني عدد كبير من الناس اللي بياخدوا ال
+
+347
+00:25:02,730 --> 00:25:06,590
+infection بتحول إلى chronic من 75 إلى 85% منهم
+
+348
+00:25:06,590 --> 00:25:11,870
+بتحول إلى chronic فقريباً 20% من المصابين بيصيرلهم
+
+349
+00:25:11,870 --> 00:25:15,990
+يعني recovery لحالهم بيطيبوا، بتكون antibodies و
+
+350
+00:25:15,990 --> 00:25:20,360
+بتعافوا من المرض بدون مشاكل خلال 6 شهورلكن هذا لا
+
+351
+00:25:20,360 --> 00:25:24,580
+يعني انه مش راح ينصاب فيه كمان مرة لأن هو زي ما
+
+352
+00:25:24,580 --> 00:25:27,540
+انتوا عارفين فيروس بيعمل Zero-conversion وبيغير
+
+353
+00:25:27,540 --> 00:25:31,420
+نفسه وهذا اللي خلّه فيه صعوبة لحدوث تطعيم دلوقتي
+
+354
+00:25:31,420 --> 00:25:33,560
+في الفيروس طبعا هي نفس الـ Progress زي ما قولنا
+
+355
+00:25:33,560 --> 00:25:38,020
+Normal liver لو كان فيه chronic hepatitis هتبدأ ال
+
+356
+00:25:38,020 --> 00:25:40,640
+liver تتغير و تصبح فيها fibrosis و بعدين serrosis
+
+357
+00:25:40,640 --> 00:25:47,640
+و بعدها ممكن تتحول لهيباتو سيلولار كارسينوما ال
+
+358
+00:25:47,640 --> 00:25:52,250
+diagnosisممكن نعمل فحصات serology لكن ماعندي فحصات
+
+359
+00:25:52,250 --> 00:25:57,050
+زي الـ hepatitis B تقول لمين في أي مرحلة acute ولا
+
+360
+00:25:57,050 --> 00:26:01,170
+chronic وانما بنستخدم الـ viral load يعني بيشوفوا
+
+361
+00:26:01,170 --> 00:26:06,310
+كمية الفيروس في الـ blood عن طريق الـ PCR الطريقة
+
+362
+00:26:06,310 --> 00:26:11,210
+التانية اللي هي using molecular nucleic acid زي
+
+363
+00:26:11,210 --> 00:26:16,030
+real-time PCR وrecomponent immunoblot assay في
+
+364
+00:26:16,030 --> 00:26:20,430
+عنديtranscription mediated amplification branch
+
+365
+00:26:20,430 --> 00:26:25,050
+DNA طبعا هذه الفحصات هي اللي قلتلكم عنها هي من
+
+366
+00:26:25,050 --> 00:26:28,530
+خلالها ما بتحدد بس إذا كان الشخص مصاب ولا لأ برضه
+
+367
+00:26:28,530 --> 00:26:31,890
+بتحدد كمية ال virus الموجودة في ال blood اللي هو
+
+368
+00:26:31,890 --> 00:26:38,300
+الهيباطاية C viral loadالآن لو احنا عملنا فحص الـ
+
+369
+00:26:38,300 --> 00:26:42,280
+ELISA أو بتقنيات المناعية الـ serology العادية طلع
+
+370
+00:26:42,280 --> 00:26:45,240
+معايا negative فهو negative الآن إذا طلع معايا
+
+371
+00:26:45,240 --> 00:26:50,120
+positive بدي أؤكد عن طريق الـ RNA إذا كان ال viral
+
+372
+00:26:50,120 --> 00:26:54,580
+RNA positive يعني الشخص هذا for sure مصاب إذا طلع
+
+373
+00:26:54,580 --> 00:26:58,760
+ال viral RNA negative بعمل recombinant immunoblot
+
+374
+00:26:58,760 --> 00:27:04,590
+assayإذا كانت positive يعني كان فيه فيروس وصار لها
+
+375
+00:27:04,590 --> 00:27:11,350
+recovery صار يعني صار شفاء منها وانتهت وإذا طلعت
+
+376
+00:27:11,350 --> 00:27:15,310
+الـ Recomponent immunoblot assay negative معنى
+
+377
+00:27:15,310 --> 00:27:19,850
+الكلام أن الفحص هذا كان false positive لأن لو
+
+378
+00:27:19,850 --> 00:27:25,580
+تلاحظته هذه negativeوالـ RNA Negative من الـ
+
+379
+00:27:25,580 --> 00:27:29,320
+Positive الوحيدة كانت الـ ELISA أو الـ Serological
+
+380
+00:27:29,320 --> 00:27:33,480
+Techniques بتكون False Negative يعني الـ Negative
+
+381
+00:27:33,480 --> 00:27:36,580
+من الأساس بأكبرها Negative الـ Positive بأكدها عن
+
+382
+00:27:36,580 --> 00:27:40,720
+طريق الـ RNA وعن طريق الـ Recombinant Immunoblot
+
+383
+00:27:40,720 --> 00:27:44,360
+الاساسي
+
+384
+00:27:44,360 --> 00:27:47,880
+في عندي زي ما قلتلكم غير الـ Viral Load ممكن نعمل
+
+385
+00:27:47,880 --> 00:27:51,300
+liver function test ممكن نعمل liver biopsy عشان
+
+386
+00:27:51,300 --> 00:27:56,210
+نشوف الـفي عندي نوعين من الـ viruses اللي هو non
+
+387
+00:27:56,210 --> 00:27:59,130
+-A، non-B hepatitis viruses في عندي Hepatitis D
+
+388
+00:27:59,130 --> 00:28:04,590
+virus الـ Hepatitis D virus مش شائع وهذا الـ virus
+
+389
+00:28:04,590 --> 00:28:09,930
+بتتميز بأنه بعيش تفال ع Hepatitis B يعني ما بعيش
+
+390
+00:28:09,930 --> 00:28:13,670
+إلا فيه عند إنسان مصاب بـ Hepatitis B يعني لحالة
+
+391
+00:28:13,670 --> 00:28:17,990
+ما بقدرش أعيش، ليش؟ لأنهباستفيد من الـ Envelope
+
+392
+00:28:17,990 --> 00:28:21,590
+بروتين عشان يعمل replication تاع Hepatitis B يعني
+
+393
+00:28:21,590 --> 00:28:25,010
+بياخد Envelope بروتين تاع Hepatitis B عشان يعمل من
+
+394
+00:28:25,010 --> 00:28:28,530
+خلاله replication Hepatitis B virus is therefore
+
+395
+00:28:28,530 --> 00:28:32,470
+الـ Helper virus for Hepatitis B Hepatitis D
+
+396
+00:28:32,470 --> 00:28:35,950
+بينتقل بنفس الطرق اللي بينتقل بيها Hepatitis B
+
+397
+00:28:35,950 --> 00:28:41,500
+اللي هو عن طريق bloodالـ Hepatitis E فيروس هذا
+
+398
+00:28:41,500 --> 00:28:45,100
+بينتقل بالـ fecal oral route و less common وأعراضه
+
+399
+00:28:45,100 --> 00:28:52,580
+بتشبه أعراض Hepatitis A طيب نيجي للـ HIV human
+
+400
+00:28:52,580 --> 00:28:57,900
+immunodeficiency virus طبعا
+
+401
+00:28:57,900 --> 00:29:03,320
+الفيروس هذا في عندنا envelope glycoprotein 20 و
+
+402
+00:29:03,320 --> 00:29:08,020
+glycoprotein 41 أو زي ما احنا عارفين مشكلته انه
+
+403
+00:29:08,020 --> 00:29:12,260
+بصيبالـ CD4-T-Helper Lymphocyte عشان هيك بدمر جهاز
+
+404
+00:29:12,260 --> 00:29:16,120
+المناعة الـ Incubation Period تتراوح من تلت سنين
+
+405
+00:29:16,120 --> 00:29:23,080
+إلى خمس السنوات Mode of Transmission طبعاً طرق
+
+406
+00:29:23,080 --> 00:29:27,080
+الانتقال للعدوى أول حاجة بشكل أساسي Sexual
+
+407
+00:29:27,080 --> 00:29:31,800
+Transmissionاستخدام الأدوات الـ intravenous
+
+408
+00:29:31,800 --> 00:29:35,060
+needles والأشياء اللي ممكن تستخدم عن طريق الـ
+
+409
+00:29:35,060 --> 00:29:38,060
+blood infect mother to her baby either across the
+
+410
+00:29:38,060 --> 00:29:41,800
+placenta or at birth or via breast milk يعني ممكن
+
+411
+00:29:41,800 --> 00:29:45,500
+ينتقل خلال الحمل أو خلال الولادة أو عن طريق
+
+412
+00:29:45,500 --> 00:29:49,160
+الرضاعة إذا كانت الأم مصابة عن طريق طبعا الـ blood
+
+413
+00:29:49,160 --> 00:29:55,440
+transfusion والـ tissue transplantation نيجي
+
+414
+00:29:55,440 --> 00:30:01,720
+للـ signs and symptoms of HIVطبعاً لما أنا أشوف
+
+415
+00:30:01,720 --> 00:30:05,920
+شخص مصاب بالـ HIV مافيش عندي عراض محددة أقول إنه
+
+416
+00:30:05,920 --> 00:30:10,540
+مريض HIV وبعدين الشخص مجرد ما ياخد العدوى ممكن
+
+417
+00:30:10,540 --> 00:30:15,580
+يكون معدي ممكن ينقل الفيروس ويمرره لعدد كبير من
+
+418
+00:30:15,580 --> 00:30:20,220
+الناس طبعا هنا بقولك it is not possible to tell
+
+419
+00:30:20,220 --> 00:30:23,740
+just by looking if someone has HIV or not يعني
+
+420
+00:30:23,740 --> 00:30:28,890
+مافيش شخص بتقدر تبطلع عليه وتقول إنه مصاب HIVولّا
+
+421
+00:30:28,890 --> 00:30:31,730
+لأ؟ يعني مافيش أراضي حالية إذا كان مريض الـ HIV
+
+422
+00:30:31,730 --> 00:30:35,830
+أمتى بيوصل لمرحلة إنه مريض AIDS مريض acquired
+
+423
+00:30:35,830 --> 00:30:41,470
+immune deficiency إذا كان وصل عدد الـ CD4 cells
+
+424
+00:30:41,470 --> 00:30:45,610
+إلى أقل من 200 خلية بالمليمتر المكعب بيصير هذا
+
+425
+00:30:45,610 --> 00:30:48,730
+الشخص عرض للعدوى وبسميه acquired immune deficiency
+
+426
+00:30:48,730 --> 00:30:53,410
+patient تمام؟الآن without treatment ممكن يعيشوا 3
+
+427
+00:30:53,410 --> 00:30:59,610
+سنوات لكن مجرد ما ياخد عدوة خطيرة ممكن يعني تنزل
+
+428
+00:30:59,610 --> 00:31:03,470
+هذه الفترة إلى سنة واحدة فقط الآن بقولك إذا كان
+
+429
+00:31:03,470 --> 00:31:06,570
+الشخص طلق علاج مناسب اللي هو Anti-retroviral
+
+430
+00:31:06,570 --> 00:31:10,130
+therapy مع low viral load كان أصلا الـ viral عنده
+
+431
+00:31:10,130 --> 00:31:14,650
+قليل ممكن يكون الـ prognosis لقيله أفضل ويعيش حياة
+
+432
+00:31:14,650 --> 00:31:19,030
+شبه طبيعية ال lab diagnosis أول حاجة الـ
+
+433
+00:31:19,030 --> 00:31:22,800
+serological screeningهو Screening خدوا بالكم يعني
+
+434
+00:31:22,800 --> 00:31:26,160
+ما بيعطيني confirmation وإنما Screen Antibody
+
+435
+00:31:26,160 --> 00:31:29,660
+detection ELISA are the most frequently used
+
+436
+00:31:29,660 --> 00:31:32,840
+method for screening of blood sample for HIV
+
+437
+00:31:32,840 --> 00:31:38,560
+antibody طبعاً هذا يعني مثلا عندي وحدات دمأ أو
+
+438
+00:31:38,560 --> 00:31:41,960
+الحاجة بياخدوا عينة وحدة الدم بياخدوا Serum من
+
+439
+00:31:41,960 --> 00:31:45,760
+البشر وبيعملوله فحص الـ Antibody عن طريق الـ ELISA
+
+440
+00:31:45,760 --> 00:31:49,950
+عشان هيك هو Screening Test تمام؟طيب، but false
+
+441
+00:31:49,950 --> 00:31:52,730
+positive and false negative reaction may occur
+
+442
+00:31:52,730 --> 00:31:55,610
+يعني ممكن تعطيني false positive أو false negative
+
+443
+00:31:55,610 --> 00:31:59,790
+another test systems available include passive
+
+444
+00:31:59,790 --> 00:32:03,230
+particle agglutination، immunofluorescence،
+
+445
+00:32:03,230 --> 00:32:07,370
+western blot، and recombinant immunoblot assay ال
+
+446
+00:32:07,370 --> 00:32:10,750
+western blot تعتبر ال gold standard للdiagnosis
+
+447
+00:32:10,750 --> 00:32:17,930
+للهيباطية للفيروس ال HIV فيروسنيجي للـ Antigen
+
+448
+00:32:17,930 --> 00:32:21,150
+احنا ممكن نلاقي الـ Antigen نقيس الـ Antigen اللي
+
+449
+00:32:21,150 --> 00:32:26,630
+هو الـ Capsid بـ 24 Antigen ممكن نقيسه عن طريق الـ
+
+450
+00:32:26,630 --> 00:32:31,430
+ELISA الـ Antigen هذا ممكن نلاقي positive في
+
+451
+00:32:31,430 --> 00:32:34,530
+المرحلة الأولى من المرض قبل ما تبدأ تظهر الـ
+
+452
+00:32:34,530 --> 00:32:38,830
+Antibody لكن بعد ما تظهر الـ Antibody ممكن يختفي
+
+453
+00:32:38,830 --> 00:32:41,250
+الـ Antigen لأنه بيكون صار له neutralization مع
+
+454
+00:32:41,250 --> 00:32:47,170
+الـ Antibody بس بعد فترةلو زادت كمية الـ Antigen
+
+455
+00:32:47,170 --> 00:32:49,610
+عن كمية الـ Antibody في الـ Late Stage أو في الـ
+
+456
+00:32:49,610 --> 00:32:52,550
+Final Stage من الـ Infection برضه ممكن يعطيني
+
+457
+00:32:52,550 --> 00:32:55,350
+Positive إذا في المرحلة الأولى بيعطيني Positive
+
+458
+00:32:55,350 --> 00:32:58,410
+بعد هيك في الـ Latent Period لما بتتوّن الـ
+
+459
+00:32:58,410 --> 00:33:01,450
+Antigen Antibody Complex بيعطيني Negative بعد هيك
+
+460
+00:33:01,450 --> 00:33:03,750
+في الـ Late Stage برضه بيعطيني Positive الـ Virus
+
+461
+00:33:03,750 --> 00:33:06,970
+Isolation طبعاً عارفين إحنا إن الـ Virus بتكاثر في
+
+462
+00:33:06,970 --> 00:33:11,150
+الـ T-Lymphocyte فممكن نجيب Cell Line من الـ T
+
+463
+00:33:11,150 --> 00:33:16,080
+-Lymphomaونزرع فيه الفيروس ونعمل viral isolation
+
+464
+00:33:16,080 --> 00:33:20,540
+طبعاً هي time-consuming ومزعجة وبتاخد أسابيع لغاية
+
+465
+00:33:20,540 --> 00:33:24,780
+ما أعزل الفيروس ممكن أعمل demonstration للـnucleic
+
+466
+00:33:24,780 --> 00:33:31,180
+acid للفيروس عن طريق الـPCR نيجي للـHIV viral load
+
+467
+00:33:31,180 --> 00:33:34,040
+أني أعرف كمية الفيروس الموجودة عند هذا الشخص عن
+
+468
+00:33:34,040 --> 00:33:40,990
+طريق الـreal-time PCRطبعًا يعني هذه بتلزمني غير
+
+469
+00:33:40,990 --> 00:33:43,310
+طبعًا إحنا في الـDiagnosis بتلزمني بتحدد ع
+
+470
+00:33:43,310 --> 00:33:46,590
+الـVirus بتحدد كمية الـVirus بتلزم في متابعة
+
+471
+00:33:46,590 --> 00:33:51,030
+العلاج إذا الشخص بياخد Antiviral Chemotherapy يعني
+
+472
+00:33:51,030 --> 00:33:55,830
+بتساعدني في معرفة المفعول العلاج أو تأثير العلاج
+
+473
+00:33:55,830 --> 00:34:00,670
+على هذا الشخص شغل تانية إذا كان المريض الـViral
+
+474
+00:34:00,670 --> 00:34:03,920
+Load عنده قليلمن البداية في فترة الـ Incubation
+
+475
+00:34:03,920 --> 00:34:07,140
+Period بيكون الـ Prognosis لإله أفضل نيجي للشغل
+
+476
+00:34:07,140 --> 00:34:10,580
+الأخيرة اللي هي الـ CD4 Count أني أعد الخلايا اللي
+
+477
+00:34:10,580 --> 00:34:15,400
+هي CD4 هذه بتقسم الـ Immune Deficiency لتلت مراحل
+
+478
+00:34:15,400 --> 00:34:19,580
+إذا كان عددها أكتر من 500 خلية بعتبر إنها Early
+
+479
+00:34:19,580 --> 00:34:23,560
+Immune Deficiency إذا كان من 200 إلى 500 بعتبرها
+
+480
+00:34:23,560 --> 00:34:28,000
+Intermediate Immune Deficiency إذا كان أقل من 200
+
+481
+00:34:28,000 --> 00:34:32,570
+بعتبرها Advanced Immune Deficiencyهيك احنا بنكون
+
+482
+00:34:32,570 --> 00:34:36,210
+أخدنا الفخاصات اللي هامنا اللي بتلزم فيه تشخيص الـ
+
+483
+00:34:36,210 --> 00:34:40,650
+HIV الـ Measurement of HIV Viral Load تخبرنا عن
+
+484
+00:34:40,650 --> 00:34:45,110
+مكان اتجاه المرض و whereas CD4 Count تخبرنا عن
+
+485
+00:34:45,110 --> 00:34:49,330
+مكان اتجاه المرض في هذه اللحظة يعني الـ HIV Viral
+
+486
+00:34:49,330 --> 00:34:53,590
+Load بقولي وين ايش مستقبل المرض لكن الـ CD4 بتقولي
+
+487
+00:34:53,590 --> 00:34:56,970
+المرض وين واصل في هذه اللحظة يعطيكوا ألف عافية
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/TwyFYt3mYTU_raw.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/TwyFYt3mYTU_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..7a40edb7b6d2e98e7b2c0295a408568d0f188238
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/TwyFYt3mYTU_raw.srt
@@ -0,0 +1,680 @@
+1
+00:00:02,260 --> 00:00:06,220
+بسم الله الرحمن الرحيم ان شاء الله رب العالمين راح
+
+2
+00:00:06,220 --> 00:00:09,220
+ناخد اليوم آخر application من ال applications
+
+3
+00:00:09,220 --> 00:00:12,500
+بتاعة ال agglutination اللي هو ال hemagglutination
+
+4
+00:00:12,500 --> 00:00:16,040
+assay أو influenza hemagglutination ال
+
+5
+00:00:16,040 --> 00:00:20,980
+hemagglutination assay أش هي ال principle بتاعته
+
+6
+00:00:20,980 --> 00:00:26,880
+ال influenza virus عادة في على ال envelope لإله
+
+7
+00:00:26,880 --> 00:00:30,480
+بروتين البروتين هذا اسمه hemagglutinin
+
+8
+00:00:32,970 --> 00:00:37,170
+البروتين هذا برتبط بالـ cellic acid receptors على
+
+9
+00:00:37,170 --> 00:00:42,130
+سطح الخلايا هو إله ميزة إنه برتبط بالـ cellic acid
+
+10
+00:00:42,130 --> 00:00:45,990
+مش antigen antibody reaction لكن الـ hemagglutinin
+
+11
+00:00:45,990 --> 00:00:50,650
+برتبط بالـ cellic acid تمام؟ الـ virus will also
+
+12
+00:00:50,650 --> 00:00:55,110
+bind to erythrocyte يعني حيرتبط بالـ erythrocyte
+
+13
+00:00:55,110 --> 00:00:57,730
+كمان يعني الـ erythrocyte إيش عليه؟ عليها cellic
+
+14
+00:00:57,730 --> 00:01:02,550
+acidهيعمل نتيجة الإرتباط هذا تكوين الـ «لاتس»
+
+15
+00:01:02,550 --> 00:01:06,530
+تكوين agglutination this property is called
+
+16
+00:01:06,530 --> 00:01:09,810
+hemeagglutination يعني هذه الـ «فايروس» إلها قدرة
+
+17
+00:01:09,810 --> 00:01:14,690
+على إنها تعمل تخثر للخلايا للـ RBCs and is the
+
+18
+00:01:14,690 --> 00:01:17,770
+basis of rapid assay to determine levels of
+
+19
+00:01:17,770 --> 00:01:21,270
+influenza virus present in the sample هذه الـ
+
+20
+00:01:21,270 --> 00:01:24,750
+property إحنا بنستخدمها الفئاش فإن عندي مثلا
+
+21
+00:01:24,750 --> 00:01:28,940
+sampleبدي أعرف تركيز الـ Influenza Virus فيها ممكن
+
+22
+00:01:28,940 --> 00:01:34,520
+تكون الـ Sample عبارة عن Cell Culture Suspension
+
+23
+00:01:34,520 --> 00:01:36,800
+يعني Suspension من Cell Culture أنا مجهزة عشان
+
+24
+00:01:36,800 --> 00:01:40,340
+أنمي فيه الـ Influenza Virus وبدي أعرف تركيز الـ
+
+25
+00:01:40,340 --> 00:01:44,760
+Virus فيه فإيش بعمل؟ بعمل Serial Dilution Two-fold
+
+26
+00:01:44,760 --> 00:01:47,680
+Serial Dilution زي ما بنعمل من الـ Suspension اللي
+
+27
+00:01:47,680 --> 00:01:53,200
+عندي و باخد عليه كمية محددة من الـ RBCsوبشوف إيش
+
+28
+00:01:53,200 --> 00:01:58,280
+آخر واحدة أعطتني agglutination باعتبر هو طبعا هذا
+
+29
+00:01:58,280 --> 00:02:01,480
+الكلام اللي حكيناه أنه الفيروس بيحتوي على
+
+30
+00:02:01,480 --> 00:02:05,520
+hemeagglutinin لو أنا الفيروس hemeagglutinin لو
+
+31
+00:02:05,520 --> 00:02:09,940
+أضفته على ال RBCs هيرتبط مع ال cellic acid ويعمل
+
+32
+00:02:09,940 --> 00:02:13,380
+عندي agglutination هي ال RBCs suspension وهي
+
+33
+00:02:13,380 --> 00:02:18,520
+الفيروس hemeagglutination virus طبعا هيكون من فصلة
+
+34
+00:02:18,520 --> 00:02:22,640
+ال influenzaشكل الـ agglutination أو شكل النتيجة
+
+35
+00:02:22,640 --> 00:02:26,900
+كيف هيكون يعني هو agglutination positive هيكون على
+
+36
+00:02:26,900 --> 00:02:29,500
+شكل انتشار في قاع الـ will اللي هو settling
+
+37
+00:02:29,500 --> 00:02:33,240
+pattern أو كيف بتنزل ال RBCs أو كيف بتتجمع ال RBCs
+
+38
+00:02:33,240 --> 00:02:37,620
+هيكون على شكل انتشار في ال will كله على خلاف ال
+
+39
+00:02:37,620 --> 00:02:40,220
+negative ال negative هتكون اتجمع ال RBCs أو
+
+40
+00:02:40,220 --> 00:02:45,040
+suspended في الوسط كيف ال procedure بتاعة الشغل؟
+
+41
+00:02:45,320 --> 00:02:50,220
+الان انا خلّيني اتذكر احنا بدنا نعمل تقدير لكمية
+
+42
+00:02:50,220 --> 00:02:54,380
+الفيروس نشوف قداش في عندي فيروس في fluid معين أو
+
+43
+00:02:54,380 --> 00:02:59,440
+في suspension من سلك الشر فبروح بجيب اللي هو
+
+44
+00:02:59,440 --> 00:03:06,220
+البلاد اللي فيه micro wells فيه wells صغيرة هلأ ات
+
+45
+00:03:06,220 --> 00:03:10,220
+راح أورجيكم إياهم ال well هادي زي كأنها أنابيب
+
+46
+00:03:10,220 --> 00:03:15,110
+صغيرةبعمل فيها الـ Serial Dilution يعني باخد خمسين
+
+47
+00:03:15,110 --> 00:03:21,570
+من الـ saline for spit buffer saline و خمسين من ال
+
+48
+00:03:21,570 --> 00:03:24,910
+suspension بتاع ال cell culture و بعمل Serial
+
+49
+00:03:24,910 --> 00:03:28,550
+Dilution بنفس الطريقة اللي اتعلمناها بعد هيك باخد
+
+50
+00:03:28,550 --> 00:03:33,210
+خمسين microliter على كل well من ال RBC suspension
+
+51
+00:03:33,210 --> 00:03:38,030
+اللي أنا محضرةوبعمل mixing باستنى من 20 إلى 30
+
+52
+00:03:38,030 --> 00:03:43,870
+دقيقة عسى إنه تيح فرصة لـRBCs إنها تتفاعل وتنزل في
+
+53
+00:03:43,870 --> 00:03:49,110
+قاع الـWell هي هتنزل إما على شكل Settling إما
+
+54
+00:03:49,110 --> 00:03:52,530
+هتنزل الـSettling Pattern هيكون إما على شكل انتشار
+
+55
+00:03:52,530 --> 00:03:56,870
+أو على شكل تجمع هذه الـWell طبعا بعمل Serial
+
+56
+00:03:56,870 --> 00:04:01,590
+Dilution بهذا الطريقة 2 4 8 16 32
+
+57
+00:04:04,990 --> 00:04:10,170
+وطبعاً الشريحة اللي بعدها راح تحكي عن كيف شكل ال
+
+58
+00:04:10,170 --> 00:04:13,570
+reaction راح يكون فخلينا احنا راح نشرحها هلقيت
+
+59
+00:04:13,570 --> 00:04:17,390
+اللي موجود ال reaction على شكل انتشار زي ما انتوا
+
+60
+00:04:17,390 --> 00:04:21,350
+شايفين هذا positive result يعني الخلايا عاملة
+
+61
+00:04:21,350 --> 00:04:25,210
+lattice عاملة agglutination بينما إذا كانت الخلايا
+
+62
+00:04:25,210 --> 00:04:29,050
+على شكل تجمع في قاع الول معنى الكلام إنها ترثبت
+
+63
+00:04:29,050 --> 00:04:32,680
+بدون ما تعمل agglutinationإذن الـ Titer هنا راح
+
+64
+00:04:32,680 --> 00:04:38,880
+يكون 128 التيتر هنا 32 التيتر هنا طيب نشوف هذه طيب
+
+65
+00:04:38,880 --> 00:04:42,180
+هل هذه positive ولا negative؟ خلوا بالكم هذه في
+
+66
+00:04:42,180 --> 00:04:46,900
+جزء منها معطي positive يعني في جزء مش مترسم هذه
+
+67
+00:04:46,900 --> 00:04:50,340
+بعتبرها برضه positive يعني هذه الـ Titer لإلها 128
+
+68
+00:04:50,340 --> 00:04:54,560
+ليش؟ لأنه لازل فيه أنتجين قادر يعطي agglutination
+
+69
+00:04:54,560 --> 00:04:58,920
+إذن التيتر هنا 128 هذه كلها negative و هذه
+
+70
+00:04:58,920 --> 00:05:02,990
+negativeهذه الـ «Titer 32» وهكذا وهذه الـ «Titer
+
+71
+00:05:02,990 --> 00:05:07,570
+8» إلى آخرها تمام؟ هيك أنا بعرف النتيجة
+
+72
+00:05:07,570 --> 00:05:11,250
+Interpretation هو الكلام اللي أنا قلته «The red
+
+73
+00:05:11,250 --> 00:05:15,570
+cells that are not bound by influenza virus sink
+
+74
+00:05:15,570 --> 00:05:20,650
+to the bottom of the well and form a button» بتعمل
+
+75
+00:05:20,650 --> 00:05:23,910
+معاكي أو بتظهر معاكي على شكل button على شكل تجمع
+
+76
+00:05:23,910 --> 00:05:28,130
+صغير بهذا الشكلالسلحان اللي ملقوا فيه مجموعات
+
+77
+00:05:28,130 --> 00:05:32,150
+فيروس تجمع لطبق تدخل الـ Will هتلاقيها مغطية كل
+
+78
+00:05:32,150 --> 00:05:36,770
+الـ Will القاعة الـ Will يعني مافيش فيه زي هذه
+
+79
+00:05:36,770 --> 00:05:40,350
+المنطقة تجمع الـ RBCs في منطقة معينة وإنها هتلاقي
+
+80
+00:05:40,350 --> 00:05:45,030
+انتشار انتشار للـ RBCs في كل مكان الـ Assay يمكن
+
+81
+00:05:45,030 --> 00:05:53,210
+ان يتم تجمعه خلال 30 دقيقةوهو فحص
+
+82
+00:05:53,210 --> 00:06:01,970
+سريع ويعطيك عدد نسبي أو تصور لقداش في عندك فيروس
+
+83
+00:06:01,970 --> 00:06:08,130
+في الـ suspension اللي حصلتي عليه في عندي
+
+84
+00:06:08,130 --> 00:06:12,160
+application تاني للهيم أجلوتناشنفي الـ
+
+85
+00:06:12,160 --> 00:06:16,380
+Hemagglutination الأول إحنا حددنا الفيروس قداش الـ
+
+86
+00:06:16,380 --> 00:06:22,020
+Titer أو قداش في عندي Viral Particles هنا العملية
+
+87
+00:06:22,020 --> 00:06:26,380
+مختلفة بدي أستخدم الـ Hemagglutination Inhibition
+
+88
+00:06:26,380 --> 00:06:31,540
+Assay هنفهم الـ Principle اللي له في إني أحدد الـ
+
+89
+00:06:31,540 --> 00:06:35,500
+Titer للـ Antibody لإنسان مصاب بهذا الفيروس يعني
+
+90
+00:06:35,500 --> 00:06:39,070
+في عندي Antibody في الـ Serumبود أشوف الـ title له
+
+91
+00:06:39,070 --> 00:06:42,970
+باستخدام الـ Hemagglutination Inhibition طيب بنشوف
+
+92
+00:06:42,970 --> 00:06:47,610
+الـ principle الـ hemagglutination can be modified
+
+93
+00:06:47,610 --> 00:06:50,830
+to determine the level of antibodies to influenza
+
+94
+00:06:50,830 --> 00:06:55,170
+virus present in serum sample the basis بتعتمد على
+
+95
+00:06:55,170 --> 00:07:00,410
+إيش of the hemagglutination inhibition assay is
+
+96
+00:07:00,410 --> 00:07:04,350
+that antibodies to influenza virus will prevent
+
+97
+00:07:04,350 --> 00:07:08,690
+attachment of the virus to red cellsيعني الـ
+
+98
+00:07:08,690 --> 00:07:15,110
+Antibodies راح تروح وهي مرتبطة مع الفيروس وبالتالي
+
+99
+00:07:15,110 --> 00:07:19,290
+هتعمله Neutralization وبالتالي مش هيتفاعل مع الـ
+
+100
+00:07:19,290 --> 00:07:25,130
+RBCs يعني هتعمله Inhibition تمام؟ إذا الـ
+
+101
+00:07:25,130 --> 00:07:28,090
+Antibodies هتعمل Inhibition للفيروس ومن هنا أجل
+
+102
+00:07:28,090 --> 00:07:30,850
+Hemagglutination Inhibition Therefore
+
+103
+00:07:30,850 --> 00:07:33,010
+Hemagglutination is inhibited
+
+104
+00:07:35,470 --> 00:07:39,950
+الأصل كان إن الـ RBCs تتفاعل مع الفيروس تعطينيهم
+
+105
+00:07:39,950 --> 00:07:44,390
+أجل التناشة لكن في وجود الـ Antibody حيصير
+
+106
+00:07:44,390 --> 00:07:47,990
+Neutralization للفيروس الفيروس هيرتبط مع الـ
+
+107
+00:07:47,990 --> 00:07:52,750
+Antibody وبالتالي مش هيرتبط مع الـ RBCs أو مش هيظل
+
+108
+00:07:52,750 --> 00:07:56,130
+كمية من الفيروس ترتبط مع الـ RBCs وتعطيني أجل
+
+109
+00:07:56,130 --> 00:08:00,120
+التناشةفبالتالي الـ Settling Pattern هيكون على شكل
+
+110
+00:08:00,120 --> 00:08:05,140
+Negative بمعنى إنه إذا كان الـ Antibody موجود وصار
+
+111
+00:08:05,140 --> 00:08:08,900
+Inhibition يعني النتيجة Positive أه Positive الـ
+
+112
+00:08:08,900 --> 00:08:11,520
+Antibody موجود يعني Positive هيعمل Inhibition
+
+113
+00:08:11,520 --> 00:08:15,220
+وبالتالي مش هيصير Agglutination فهيكون الـ
+
+114
+00:08:15,220 --> 00:08:20,920
+Positive على شكل Button اللي قلنا عنها زي تجمع للـ
+
+115
+00:08:20,920 --> 00:08:26,300
+RBC في قاع الولي، تمام؟يعني الـ positive result no
+
+116
+00:08:26,300 --> 00:08:31,240
+agglutination طبعا
+
+117
+00:08:31,240 --> 00:08:37,020
+هنا كيف طريقة الشغل تبعته يعني الفكرة بتعتمد على
+
+118
+00:08:37,020 --> 00:08:42,340
+أنه أنا بدي أحط الـ serum أعمل منه cereal dilution
+
+119
+00:08:42,340 --> 00:08:46,320
+اللي بدي أعمله titration وأحط عليه شغلتين بدي أحط
+
+120
+00:08:46,320 --> 00:08:51,250
+عليه الـ virusتمام قدش بنحط فيروس بنحط كمية محددة
+
+121
+00:08:51,250 --> 00:08:55,730
+من الفيروس مكافئة إلى 32 إلى 64 Hemagglutination
+
+122
+00:08:55,730 --> 00:09:03,870
+Unit من الـ Viral Suspension وبحط برضه كمية من الـ
+
+123
+00:09:03,870 --> 00:09:07,010
+RBCs إذا الويل بدي يكون فيه Serial Dilution من
+
+124
+00:09:07,010 --> 00:09:10,770
+السيرام بدي يكون فيه Drop من الـ Viral Suspension
+
+125
+00:09:10,770 --> 00:09:15,440
+وبدي يكون فيه Drop من الـ RBCsبكل ويل من الـ 96
+
+126
+00:09:15,440 --> 00:09:18,260
+ويل طبعا البلات اللي انت شفته فيه 96 ويل اللي أنا
+
+127
+00:09:18,260 --> 00:09:23,140
+بستخدمه لـ titration بكل ويل من الـ 96 ويل هيكون
+
+128
+00:09:23,140 --> 00:09:28,000
+فيه 3 شغلات هذه serum و virus virus suspension و
+
+129
+00:09:28,000 --> 00:09:35,580
+RBCs تمام بحطهم مع بعض و بستنى عليهم 30 دقيقةكيف
+
+130
+00:09:35,580 --> 00:09:39,940
+طريقة الشغل؟ هنا بقولك أول حاجة طبعا بعمل labeling
+
+131
+00:09:39,940 --> 00:09:43,880
+للبلاد بعدين باخد خمسين microliter من الـ
+
+132
+00:09:43,880 --> 00:09:47,740
+Phosphate Buffer Saline وطبعا خمسين microliter من
+
+133
+00:09:47,740 --> 00:09:51,140
+السيرم بحضر الـ Serial Dilution بعدين بحط خمسين
+
+134
+00:09:51,140 --> 00:09:54,580
+microliter من الفيروس بعد ما بحط الخمسين
+
+135
+00:09:54,580 --> 00:09:57,960
+microliter من الفيروس بستنى تلاتين دقيقة إيش الهدف
+
+136
+00:09:57,960 --> 00:10:01,400
+منها هذه؟ أني أسمح للـ Antibodies اللي في السيرم
+
+137
+00:10:01,400 --> 00:10:05,020
+أنها تتفاعل مع الفيروسوتعمله neutralization إذا
+
+138
+00:10:05,020 --> 00:10:12,060
+كانت موجودة تمام بعد هيك يعني بحط ال RBCs و بستنى
+
+139
+00:10:12,060 --> 00:10:16,540
+كمان 30، 20 إلى 30 دقيقة و بشوف النتيجة هلاقيت
+
+140
+00:10:16,540 --> 00:10:21,060
+يعني في الخطوة الأولى أنا حطيت ال antibody مع
+
+141
+00:10:21,060 --> 00:10:24,580
+الفيروس إذا كان ال antibody موجود هيعمل
+
+142
+00:10:24,580 --> 00:10:27,080
+neutralization للفيروس فبالتالي الفيروس مش هيقدر
+
+143
+00:10:27,080 --> 00:10:30,080
+يعمل hemagglutination في المرحلة التانية إذا كان
+
+144
+00:10:30,080 --> 00:10:33,610
+مش موجود هيعمل الفيروس hemagglutinationفي هذه
+
+145
+00:10:33,610 --> 00:10:39,070
+المرحلة وهذه
+
+146
+00:10:39,070 --> 00:10:43,630
+النتائج عندي طبعا هذا نوع agglutination يعني
+
+147
+00:10:43,630 --> 00:10:51,290
+positive الـ titer 64 الـ titer هنا 32
+
+148
+00:10:51,290 --> 00:10:58,510
+الـ titer هنا 16هذه برضه الـ Titer 32 ليش اعتبرها
+
+149
+00:10:58,510 --> 00:11:02,470
+هيك؟ لأنه لازال فيه Antibody قادر تعمل إبلوك
+
+150
+00:11:02,470 --> 00:11:09,650
+للفيروس ويعطيه Partial Inhibition وهكذا، تمام؟
+
+151
+00:11:09,650 --> 00:11:13,010
+النتيجة هذه هتكون Negative لأن كله عامل
+
+152
+00:11:13,010 --> 00:11:15,970
+Agglutination يعني مش عامل الـ Antibody مش عامل
+
+153
+00:11:15,970 --> 00:11:16,730
+عندي Inhibition
+
+154
+00:11:19,930 --> 00:11:23,470
+الـ Interpretation of result طبعا عارفين احنا ان
+
+155
+00:11:23,470 --> 00:11:26,710
+الـ highest dilution اللي بعطيني positive reaction
+
+156
+00:11:26,710 --> 00:11:30,090
+بسميه الـ hemagglutination inhibition titer of the
+
+157
+00:11:30,090 --> 00:11:35,570
+serum إذا كان السيرم مافيش فيه antibodies مش
+
+158
+00:11:35,570 --> 00:11:38,990
+هيعطيني طبعا هيعطيني negative reaction يعني هيكون
+
+159
+00:11:38,990 --> 00:11:43,530
+فيه hemagglutination طبعا عشان بقولك if antibodies
+
+160
+00:11:43,530 --> 00:11:46,130
+to virus are present يعني إذا كان ال antibodies
+
+161
+00:11:46,130 --> 00:11:50,060
+للفيروس موجودةلازم يصير لها dilution كافة اللي هو
+
+162
+00:11:50,060 --> 00:11:53,180
+في القنابيب الأخيرة عشان يصير عندي visible heme
+
+163
+00:11:53,180 --> 00:11:56,260
+agglutination يعني heme agglutination will not be
+
+164
+00:11:56,260 --> 00:11:58,660
+observed until the antibodies are sufficiently
+
+165
+00:11:58,660 --> 00:12:01,500
+diluted يعني هذا اللي بيصير في آخر القنابيب لما
+
+166
+00:12:01,500 --> 00:12:04,380
+بعمل titration آخر القنابيب هيكون الـ antibody
+
+167
+00:12:04,380 --> 00:12:08,140
+diluted وبالتالي هيبدأ يظهر الـ heme agglutination
+
+168
+00:12:08,140 --> 00:12:11,780
+يعني الـ antibody ماقدرش يشتغل أو يرتبط بالفيروس
+
+169
+00:12:11,780 --> 00:12:15,020
+ويمنعه من الشغل هيك بنكون خلصنا الـ heme
+
+170
+00:12:15,020 --> 00:12:17,710
+agglutinationوالـ Hemagglutination Inhibition
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/V_Ub9yWovLk.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/V_Ub9yWovLk.srt
new file mode 100644
index 0000000000000000000000000000000000000000..3904bca441d14727fa4600afd246ab0eec447efb
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/V_Ub9yWovLk.srt
@@ -0,0 +1,1422 @@
+1
+00:00:20,320 --> 00:00:23,500
+طبعاً كل الكلام اللي حكيناه كان يتناول الـ
+
+2
+00:00:23,500 --> 00:00:27,040
+precipitation لما يحدث في liquid media وكيف ممكن
+
+3
+00:00:27,040 --> 00:00:29,960
+نقرأه بالتربيدومتري أو بالنفلومتري وكل الأشياء
+
+4
+00:00:29,960 --> 00:00:35,060
+اللي حكيناها لها علاقة بالـ liquid media نيجي للـ
+
+5
+00:00:35,060 --> 00:00:37,460
+precipitation in gel يعني زي ما صار ال
+
+6
+00:00:37,460 --> 00:00:41,500
+precipitation في liquid media ممكن يصير في gel
+
+7
+00:00:41,500 --> 00:00:49,680
+media. Precipitation in gel. Immune precipitate can
+
+8
+00:00:49,680 --> 00:00:53,160
+form not only in solution but also in an agar
+
+9
+00:00:53,160 --> 00:00:57,720
+matrix. يعني لو أنا استخدمت agar matrix حطيت الـ
+
+10
+00:00:57,720 --> 00:01:01,060
+Antigen والـ Antibody في اتجاه بعض، قريب من بعض
+
+11
+00:01:01,060 --> 00:01:04,560
+هتلاقي أنه هيصير diffusion ما بين الـ Antigen و
+
+12
+00:01:04,560 --> 00:01:08,660
+الـ Antibody، ويصلوا لمرحلة معينة أو لخط معين عند
+
+13
+00:01:08,660 --> 00:01:13,020
+الالتقاء، هيكونوا precipitation line، هيكونوا خط من
+
+14
+00:01:13,020 --> 00:01:15,980
+الـ precipitation when Antigen and Antibody
+
+15
+00:01:15,980 --> 00:01:19,350
+diffuse towards one another in agar, or when
+
+16
+00:01:19,350 --> 00:01:21,950
+antibody is incorporated. يعني هذا الخيار الأول
+
+17
+00:01:21,950 --> 00:01:25,550
+اللي أنا شرحته. الخيار الثاني، أحياناً أنا بكون دامجة
+
+18
+00:01:25,550 --> 00:01:28,930
+أو خالطة الـ antibody بالجل نفسه، بالـ gel matrix
+
+19
+00:01:28,930 --> 00:01:33,370
+تمام، وبحط antigen هنا برضه، هيظهر عندي visible
+
+20
+00:01:33,370 --> 00:01:37,810
+line of precipitation as in precipitation reaction
+
+21
+00:01:37,810 --> 00:01:41,770
+in liquid. نفس الكلام اللي حكيناه في الـ liquid، ال
+
+22
+00:01:41,770 --> 00:01:44,610
+precipitation line هذا، أو الـ visible precipitation
+
+23
+00:01:44,610 --> 00:01:48,580
+بيصير في الـ equivalence zone. يعني لا حيصير في منطقة
+
+24
+00:01:48,580 --> 00:01:51,880
+الـ Antigen excess، ولا حيصير في منطقة الـ Antibody
+
+25
+00:01:51,880 --> 00:01:56,240
+excess، هيصير في منطقة الـ equivalent zone. يعني هيضل
+
+26
+00:01:56,240 --> 00:02:00,980
+الاثنين يمشوا لغاية ما يصير فيه تكافؤ في التركيز، و
+
+27
+00:02:00,980 --> 00:02:07,020
+يبين عندي cut من الـ precipitation. هلقيت
+
+28
+00:02:07,020 --> 00:02:10,380
+الـ immune diffusion هو، طبعاً احنا بنسميه الـ immune
+
+29
+00:02:10,380 --> 00:02:14,520
+diffusion، اللي هو الـ precipitation in gel، بسميه
+
+30
+00:02:14,520 --> 00:02:18,410
+immunodiffusion. الـ Immunodiffusion هو الصحيح. نوعين،
+
+31
+00:02:18,410 --> 00:02:23,770
+نوع بسميه Passive، ونوع Active. الـ Passive ما بستخدمش
+
+32
+00:02:23,770 --> 00:02:26,790
+فيه أي محفز لحركة الـ Antigen أو الـ Antibody، يعني
+
+33
+00:02:26,790 --> 00:02:30,010
+ما بستخدم فيه تيار كهربائي. النوع الثاني الـ Active،
+
+34
+00:02:30,010 --> 00:02:34,170
+بستخدم فيه تيار كهربائي، بيسرّع وصول الـ Antigen للـ
+
+35
+00:02:34,170 --> 00:02:37,670
+Antibody، وكلاهما، تمام؟ هنبدأ في الـ Passive Immune
+
+36
+00:02:37,670 --> 00:02:42,050
+Diffusion، ونوعه Passive Immune Diffusion Reactions
+
+37
+00:02:42,050 --> 00:02:46,510
+of antigens and antibodies in agar gel. إيش بسميه؟
+
+38
+00:02:46,510 --> 00:02:51,070
+Immune diffusion. تمام؟ migrate to reach each other
+
+39
+00:02:51,070 --> 00:02:54,810
+and where they meet in optimal proportion for a
+
+40
+00:02:54,810 --> 00:02:59,130
+precipitation. هيمشوا باتجاه بعض، وعندما يصير
+
+41
+00:02:59,130 --> 00:03:05,230
+التركيز متناسب، هيعملوا precipitation. ليش سميناها
+
+42
+00:03:05,230 --> 00:03:08,730
+passive؟ Because they are allowed to react to
+
+43
+00:03:08,730 --> 00:03:13,870
+completion. لأن أنا بسيبهم يتفاعلوا للنهاية بدون
+
+44
+00:03:13,870 --> 00:03:18,490
+enhancement، بدون ما أضيف أي إضافات أو محفزات
+
+45
+00:03:18,490 --> 00:03:23,490
+مثل التيار الكهربائي. Factors affecting rate of
+
+46
+00:03:23,490 --> 00:03:28,430
+diffusion. إيش هي العوامل اللي بتؤثر على الـ rate of
+
+47
+00:03:28,430 --> 00:03:32,970
+diffusion؟ أول حاجة، Size of particles، الـ
+
+48
+00:03:32,970 --> 00:03:35,750
+temperature، الـ gel viscosity and hydration،
+
+49
+00:03:35,750 --> 00:03:39,830
+interaction of reactants with gel. يعني هل الـ
+
+50
+00:03:39,830 --> 00:03:45,010
+reactants هذه بترتبط أو بتتفاعل مع الجل، ولا ما
+
+51
+00:03:45,010 --> 00:03:51,630
+بتتفاعل. هذه هي العوامل بتأثر على سرعة الحركة. types
+
+52
+00:03:51,630 --> 00:03:58,690
+of immunodiffusion. فينا نوعين، نوع بيسموه radial
+
+53
+00:03:58,690 --> 00:04:03,960
+immunodiffusion، اللي هو Mani-Sinai method، والـ double
+
+54
+00:04:03,960 --> 00:04:09,380
+immune diffusion، بيسموه Ouchterlony method. الاثنين
+
+55
+00:04:09,380 --> 00:04:17,280
+بنستخدم فيهم semi-solid media، اللي هو الأجار. نيجي
+
+56
+00:04:17,280 --> 00:04:22,180
+للـ radial immunodiffusion. الـ radial immunodiffusion
+
+57
+00:04:22,180 --> 00:04:31,850
+عادة، تخيلوا معي، هذا هو الأجار. الأجار نفسه بيكون
+
+58
+00:04:31,850 --> 00:04:36,650
+مخلوط بالـ Antibody. يعني تركيز الـ Antibody متجانس
+
+59
+00:04:36,650 --> 00:04:40,510
+في كل مكان من الأجار، ثابت. تركيز الـ Antibody ثابت،
+
+60
+00:04:40,510 --> 00:04:44,430
+ثابت. بنروح بنعمل ثقوب دائرية صغيرة، طبعاً مش إحنا اللي
+
+61
+00:04:44,430 --> 00:04:50,350
+بنعملها، بيكون جاهز، هو ثقوب دائرية صغيرة في الأجار، بنحط
+
+62
+00:04:50,350 --> 00:04:54,310
+فيه الـ Sample اللي فيها الـ Antigen. تمام؟ هلقيت
+
+63
+00:04:54,310 --> 00:04:59,560
+الـ Antigen هيبدأ يمشي في كل الاتجاهات، يعمل
+
+64
+00:04:59,560 --> 00:05:03,900
+diffusion على الدائرة، بكل اتجاهات الدائرة، في كل
+
+65
+00:05:03,900 --> 00:05:09,020
+اتجاه. هيعمل radial diffusion. طبعاً أعلى تركيز للـ
+
+66
+00:05:09,020 --> 00:05:12,140
+Antigen وين؟ في موقع site of application. أنا
+
+67
+00:05:12,140 --> 00:05:16,760
+حطيت الـ Antigen هنا، هيكون إليه أعلى تركيز، مظبوط؟
+
+68
+00:05:16,760 --> 00:05:21,920
+وكل ما الـ Antigen ابتعد، كل ما تركيزه قلّ. تمام
+
+69
+00:05:21,920 --> 00:05:27,840
+هيك؟ طيب، هلقيت؟ أمتى بيظهر الـ reaction؟ اتبعوا
+
+70
+00:05:27,840 --> 00:05:32,180
+معي. هلقيت إحنا قلنا الـ Antibody تركيزه ثابت في كل
+
+71
+00:05:32,180 --> 00:05:36,460
+مكان. الـ Antigen هنا تركيزه كبير، هيبقى الـ Antigen
+
+72
+00:05:36,460 --> 00:05:41,640
+يمشي ويتخفف، يمشي ويتخفف. عندما يصل الـ
+
+73
+00:05:41,640 --> 00:05:45,440
+equivalence zone، أنه يبقى متكافئ مع كمية الـ
+
+74
+00:05:45,440 --> 00:05:49,060
+Antibody الموجودة فعلياً في الأجار، هيعمل عند الـ
+
+75
+00:05:49,060 --> 00:05:52,580
+precipitation line. يعني نفترض أن هذه الدائرة هي
+
+76
+00:05:52,580 --> 00:05:55,220
+الـ precipitation line، في المنطقة اللي فيها
+
+77
+00:05:55,220 --> 00:05:57,960
+equivalence، تكافؤ بين كمية الـ Antigen والـ
+
+78
+00:05:57,960 --> 00:06:02,920
+Antibody. طيب، المنطقة الخارجية هذه إيش باعتبرها؟
+
+79
+00:06:02,920 --> 00:06:06,420
+Zone of antibody excess. هنا الـ antibody زيادة، لأن
+
+80
+00:06:06,420 --> 00:06:10,200
+الـ antigen هيتخفف كثيراً وهو يمشي. المنطقة اللي هنا
+
+81
+00:06:10,200 --> 00:06:14,500
+اللي جوا هذه باعتبرها zone of antigen excess. ليش؟ لأن الـ antigen لازال تركيزه عالي
+
+82
+00:06:14,500 --> 00:06:18,440
+في هذه المنطقة. إذن، راح يصير التفاعل وين؟ على شكل
+
+83
+00:06:18,440 --> 00:06:25,300
+دائرة. وين الدائرة هذه هتكون؟ عند الـ Zone of
+
+84
+00:06:25,300 --> 00:06:28,940
+Equivalence. طبيعي، كل ما كان تركيز الـ Antigen أكبر،
+
+85
+00:06:28,940 --> 00:06:33,140
+يعني يطوّل أكثر لغاية ما يوصل للـ Zone of
+
+86
+00:06:33,140 --> 00:06:38,400
+Equivalence. فبالتالي، هيتسع قطر الدائرة. إذن قطر
+
+87
+00:06:38,400 --> 00:06:42,160
+الدائرة يتناسب تناسباً طردياً مع تركيز الـ Antigen.
+
+88
+00:06:42,160 --> 00:06:45,940
+تمام؟ هتقول Radial Immune Diffusion. Antigen
+
+89
+00:06:45,940 --> 00:06:51,100
+sample is placed. أولاً، نضعها في الـ well، و
+
+90
+00:06:51,100 --> 00:06:55,040
+allowed to diffuse into agar. إيش الـ agar فيه؟
+
+91
+00:06:55,040 --> 00:06:58,620
+containing a soluble dilution of antiserum، فيه
+
+92
+00:06:58,620 --> 00:07:02,500
+antibody. As the antigen diffuses into the agar،
+
+93
+00:07:02,500 --> 00:07:06,460
+هلقيت، لما يبدأ الـ antigen يعمل diffusion في الـ
+
+94
+00:07:06,460 --> 00:07:09,760
+agar، تمام؟ the region of equivalence is
+
+95
+00:07:09,760 --> 00:07:13,760
+established. سنصل لمنطقة الـ equivalence، و
+
+96
+00:07:13,760 --> 00:07:18,120
+a ring of precipitation will form. A precipitation
+
+97
+00:07:18,120 --> 00:07:21,420
+ring forms around the well. هتتكون عندي precipitation ring.
+
+98
+00:07:21,420 --> 00:07:26,580
+The area of the precipitin ring is proportional to
+
+99
+00:07:26,580 --> 00:07:30,640
+the concentration of antigen. اللي هي مساحة أو قطر
+
+100
+00:07:30,640 --> 00:07:36,060
+الدائرة هذه، أو مساحتها، تتناسب طردياً مع الـ antigen،
+
+101
+00:07:36,060 --> 00:07:40,820
+تركيز الـ antigen. ليش؟ زي ما قلت لكم، أنه كل ما التركيز
+
+102
+00:07:40,820 --> 00:07:48,180
+أكثر، يحتاج يقطع مسافة أطول، عشان يصل لتخفيفه لدرجة
+
+103
+00:07:48,180 --> 00:07:49,760
+المناسبة، أنه يعمل precipitation.
+
+104
+00:07:53,980 --> 00:07:58,660
+برضه، هدفي two methods. في عندي end point method، أنه
+
+105
+00:07:58,660 --> 00:08:01,520
+أنا بخلي الـ reaction يوصل للآخر، ويتكون الـ
+
+106
+00:08:01,520 --> 00:08:05,280
+precipitation line، أو أقيس القطر. أو kinetic، أني
+
+107
+00:08:05,280 --> 00:08:09,620
+بأخذ القراءات على أوقات معينة. هذه الطريقة تعتبر
+
+108
+00:08:09,620 --> 00:08:13,060
+quantitative technique. وإحنا هنشتغل الـ end point
+
+109
+00:08:13,060 --> 00:08:16,040
+method. أني هسيبها لليوم الثاني، لغاية ما يكتمل التفاعل
+
+110
+00:08:16,040 --> 00:08:19,600
+ويكون عندي visible line، وأجي أقرأه تاني يوم.
+
+111
+00:08:22,670 --> 00:08:26,610
+بقي أنا تركت الـ Antigen يعمل diffusion، واتكون
+
+112
+00:08:26,610 --> 00:08:30,890
+عندي دوائر. هي عندي هذا الشكل، ممكن يكون، تخيّلوا
+
+113
+00:08:30,890 --> 00:08:34,390
+عندي هذه الدائرة مثلاً، هذه أكبر واحدة، بعد هيك هذه
+
+114
+00:08:34,390 --> 00:08:37,610
+وهذه، وهذه كبيرة، وهذه صغيرة. يعني هنا تركيز الـ Antigen
+
+115
+00:08:37,610 --> 00:08:41,650
+أقل شيء في هذا الخط. طيب، أنا كيف بعرف تركيز الـ
+
+116
+00:08:41,650 --> 00:08:46,790
+Antigen من خلال الدائرة اللي عندي؟ تابعوا معي، هي
+
+117
+00:08:46,790 --> 00:08:51,400
+عندي Calibrator، هذا الأولاني. Calibrators، تركيز
+
+118
+00:08:51,400 --> 00:08:56,680
+مختلفة، هتعطيني أقطار مختلفة. بأقيس الأقطار، وأرسم
+
+119
+00:08:56,680 --> 00:09:00,780
+علاقة بيانية. X-axis عليها التركيز، ده على
+
+120
+00:09:00,780 --> 00:09:05,280
+الـ Calibrators. الـ Y-axis عليه القطر، وأعمل علاقة
+
+121
+00:09:05,280 --> 00:09:09,720
+بيانية. بسير أي دائرة ظهرت عندي، بأقيس القطر
+
+122
+00:09:09,720 --> 00:09:17,000
+بتاعها، وبنزله على الخط اللي طلع معي. هذه الطريقة
+
+123
+00:09:17,000 --> 00:09:20,420
+كويسة، وتعطي نتائج quantitative. أحياناً إحنا في الـ
+
+124
+00:09:20,420 --> 00:09:23,720
+«كيت» في عندنا طريقة أسهل بكثير، يعني هو بيكون معكِ
+
+125
+00:09:23,720 --> 00:09:28,120
+sheet، كل رقم، قد إيش قطره يقابله concentration، يعني
+
+126
+00:09:28,120 --> 00:09:31,060
+بدون أنكِ تتعبين حالكِ، وترسمي، هو حاسبها
+
+127
+00:09:31,060 --> 00:09:38,480
+وانطلعها مباشرةً. أنتِ فقط مجرد أنكِ تشوفي نص
+
+128
+00:09:38,480 --> 00:09:42,380
+القطر، وتقارنيه بالـ sheet اللي معكِ، فبيطلع معكِ
+
+129
+00:09:42,380 --> 00:09:50,340
+التركيز الـ Antigen في العينة. تمام. الشريحة هذه بتوضح
+
+130
+00:09:50,340 --> 00:09:54,100
+لنا كيف بنرسم الـ curve. في عندي هنا الـ Diameter، و
+
+131
+00:09:54,100 --> 00:10:02,940
+هنا الـ Concentration. بعض
+
+132
+00:10:02,940 --> 00:10:06,360
+مصادر الخطأ في الـ Radial Immune Diffusion. أول
+
+133
+00:10:06,360 --> 00:10:10,240
+حاجة، Over or Under filling of the well. هذه الـ
+
+134
+00:10:10,240 --> 00:10:13,540
+well بيبقى حجمه صغير، ومطلوب مني أحط فيه خمسة
+
+135
+00:10:13,540 --> 00:10:17,030
+microliter، خمسة مايكرو. ممكن أنتم عمركم ما اشتغلتم على
+
+136
+00:10:17,030 --> 00:10:20,650
+خمسة مايكرو لتر، كمية قليلة جداً، فبالتالي أي خلل
+
+137
+00:10:20,650 --> 00:10:24,490
+هيكون له تأثير كبير جداً. Spilling sample onto the
+
+138
+00:10:24,490 --> 00:10:28,510
+outside of the well. يعني لو صار الـ sample طرششت، أو
+
+139
+00:10:28,510 --> 00:10:31,870
+طلعت خارج الـ well، وأنا بشتغل، هتعمل عندي مشكلة.
+
+140
+00:10:31,870 --> 00:10:36,710
+Nicking the well with the pipette. لو أنا وأنا
+
+141
+00:10:36,710 --> 00:10:40,910
+بفوت على الـ well، الـ well طبعاً صغير جداً، وخدشتُه
+
+142
+00:10:40,910 --> 00:10:45,330
+أنا بالـ pipette، هؤثر عندي على القراءة طبعاً.
+
+143
+00:10:45,330 --> 00:10:48,450
+Improper incubation time or temperature. لو كان الـ
+
+144
+00:10:48,450 --> 00:10:51,870
+incubation time مش صحيح، أو الـ temperature مش صحيحة،
+
+145
+00:10:51,870 --> 00:10:56,290
+بيعطيني نتائج خاطئة. Incorrect measuring of the
+
+146
+00:10:56,290 --> 00:10:59,650
+wells. يعني لو أنا ما قست الـ wells بالشكل الصحيح
+
+147
+00:10:59,650 --> 00:11:07,430
+والسليم، اللي هو الـ Diameter. في
+
+148
+00:11:07,430 --> 00:11:10,390
+الـ Ouchterlony، أو النوع الثاني، أو double immune
+
+149
+00:11:10,390 --> 00:11:15,160
+diffusion، الوضع مختلف، في أنه أنا في عندي two wells،
+
+150
+00:11:15,160 --> 00:11:18,640
+كل واحد بحط فيه شيء، واحد بحط فيه الـ antibody،
+
+151
+00:11:18,640 --> 00:11:22,900
+واحد بحط فيه الـ antigen، وهيصير لهم diffusion، طبعاً
+
+152
+00:11:22,900 --> 00:11:25,840
+الـ diffusion هيكون في كل الاتجاهات،  لأن كأننا
+
+153
+00:11:25,840 --> 00:11:29,240
+ندور على المنطقة اللي يعني بدهم يتجهوا لبعض فيها،
+
+154
+00:11:29,240 --> 00:11:33,920
+هيوصلوا لحد معين، اللي هي الـ zone of equivalence،
+
+155
+00:11:33,920 --> 00:11:37,440
+ويظهر عندي line of precipitation. طبعاً عند الـ line
+
+156
+00:11:37,440 --> 00:11:41,280
+of precipitation، على اليمين في antigen axis، وعلى الشمال
+
+157
+00:11:41,280 --> 00:11:45,660
+في عندي Antibody excess. تمام؟ As equivalence is
+
+158
+00:11:45,660 --> 00:11:48,400
+reached، a visible line of precipitation. اللي هو
+
+159
+00:11:48,400 --> 00:11:51,920
+بنسميه precipitant line. هذا الـ Ouchterlony Double
+
+160
+00:11:51,920 --> 00:11:56,240
+Immune Diffusion. ما بنقدرش نعمله كـ quantitative test، بنعمل
+
+161
+00:11:56,240 --> 00:12:02,670
+ه كـ qualitative test، عشان نشوف درجة التشابه. طبعاً زي
+
+162
+00:12:02,670 --> 00:12:06,130
+ما إحنا شايفين، هاي الـ well plate اللي بحط فيه
+
+163
+00:12:06,130 --> 00:12:09,830
+الـ ... بفتح فيه الـ wells، وبأعمل فيه الشغل بتاعي. فيه
+
+164
+00:12:09,830 --> 00:12:13,910
+عندي well في الوسط، الوسط، عادةً بحط فيه الـ antibody،
+
+165
+00:12:13,910 --> 00:12:18,830
+وهنا بحط الـ antigen. عادةً بنحط antigen known، وجنبه
+
+166
+00:12:18,830 --> 00:12:22,390
+antigen unknown، عشان ندرس درجة التقارب ما بين الـ
+
+167
+00:12:22,390 --> 00:12:24,810
+antigen known، والـ antigen unknown. عادةً هنشوف
+
+168
+00:12:24,810 --> 00:12:28,630
+النتيجة، تمام؟ بعملهم incubation، بانتظر لغاية ما
+
+169
+00:12:28,630 --> 00:12:32,490
+تتكون الـ bands، أو الـ precipitation line. طبعاً زي ما
+
+170
+00:12:32,490 --> 00:12:35,650
+قلت لكم، هو عبارة عن qualitative technique، ما
+
+171
+00:12:35,650 --> 00:12:41,970
+بيعطيني تركيز، وإنما بيعطيني درجة، بيعبر عندي
+
+172
+00:13:01,380 --> 00:13:06,560
+Antigen X. الـ Antigen هذا رقم واحد known، يعني أنا
+
+173
+00:13:06,560 --> 00:13:10,340
+عارفة، وعارفة كل الـ Epitopes تبعه. فلقيت في عندي
+
+174
+00:13:10,340 --> 00:13:16,440
+Antigen مجهول، بدي أشوف درجة التقارب ما بين الـ
+
+175
+00:13:16,440 --> 00:13:19,660
+Antigen المجهول، والـ Antigen رقم واحد. نفترض الـ
+
+176
+00:13:19,660
+
+223
+00:16:56,800 --> 00:17:01,380
+كهربائي لتسهيل عملية الـ … تسهيل عملية الـ
+
+224
+00:17:01,380 --> 00:17:04,880
+Immunodiffusion can be combined with
+
+225
+00:17:04,880 --> 00:17:07,680
+electrical current to speed things up. مش هنيسر
+
+226
+00:17:07,680 --> 00:17:10,400
+يعني العملية أنت لو يعني شوفته الـ Passive الـ
+
+227
+00:17:10,400 --> 00:17:13,770
+Passive إحنا بنشتغله إن شاء الله يعني هتشتغله الـ
+
+228
+00:17:13,770 --> 00:17:17,550
+Passive بنحطه و تاني يوم أو تالت يوم نيجي ناخد
+
+229
+00:17:17,550 --> 00:17:21,630
+النتيجة نقرأ النتيجة بعد يوم أو يومين بينما هذا
+
+230
+00:17:21,630 --> 00:17:25,250
+ممكن خلال ساعة يكون أعطاكي نتيجة. Electrophoresis
+
+231
+00:17:25,250 --> 00:17:29,470
+بستخدمه بفصل فيه الـ Antigen، بعد هيك بضيف Antibody
+
+232
+00:17:29,470 --> 00:17:33,830
+هيتفاعل مع الـ Separated Antigen ويعطيني
+
+233
+00:17:33,830 --> 00:17:37,910
+Precipitation Line أو Band. Electrophoresis is a
+
+234
+00:17:37,910 --> 00:17:40,210
+technique which separates molecules using
+
+235
+00:17:40,210 --> 00:17:43,350
+electrical current. عارفينها هذه for
+
+236
+00:17:43,350 --> 00:17:47,430
+immunoelectrophoresis. Antigen and antibody migrate
+
+237
+00:17:47,430 --> 00:17:53,850
+faster. هتصير عملية الحركة أسرع. can be
+
+238
+00:17:53,850 --> 00:17:56,890
+single orderable. ممكن يكون single orderable
+
+239
+00:17:56,890 --> 00:18:00,310
+الأنواع بتاعتها هي هناخدها واحد واحد
+
+240
+00:18:00,310 --> 00:18:05,930
+immunoelectrophoresis, rocket electroimmune
+
+241
+00:18:05,930 --> 00:18:10,070
+diffusion, counter immunoelectrophoresis
+
+242
+00:18:10,070 --> 00:18:14,830
+immunofixation. تمام؟ كل واحدة إلها يعني مفهوم قعدنا
+
+243
+00:18:14,830 --> 00:18:18,210
+هنشوف يعني يا دي ليش روكت وها دي مش عارف كله هناخده
+
+244
+00:18:18,210 --> 00:18:22,050
+إن شاء الله طيب
+
+245
+00:18:22,050 --> 00:18:27,750
+هنيجي أول حاجة لـ Immuno Electrophoresis، أول نوع
+
+246
+00:18:27,750 --> 00:18:31,610
+اللي هو الـ Immuno Electrophoresis. أول حاجة بتميز
+
+247
+00:18:31,610 --> 00:18:36,190
+بإنه Two Dimensional Electrophoresis، يعني الـ
+
+248
+00:18:36,190 --> 00:18:40,130
+Separation بيصير باتجاهين متعاكسين، يعني أول حاجة
+
+249
+00:18:40,130 --> 00:18:44,560
+بفصل باتجاه، بعد هيك بدير اتجاه التيار الكهربائي في
+
+250
+00:18:44,560 --> 00:18:49,320
+اتجاه عمودي على اتجاه الأول، هلّقت هارفهم كيف؟ أول
+
+251
+00:18:49,320 --> 00:18:52,720
+حاجة بتخيلوا عندي مثلا serum sample فيها خليط من
+
+252
+00:18:52,720 --> 00:18:55,960
+البروتينة، قعدت فيها ألبومين، فيها Globulin and so
+
+253
+00:18:55,960 --> 00:19:02,800
+on. بحط الانتجين هنا و بمشي تيار كهربائي بحيث أنه
+
+254
+00:19:02,800 --> 00:19:06,600
+طبعا فيه بيكون عندي control عشان أعرف كل بروتين أو
+
+255
+00:19:06,600 --> 00:19:10,740
+كل مادة أنا بدي أفصلها منظهرة في عندي marker، تمام؟
+
+256
+00:19:11,030 --> 00:19:15,010
+بحط الـ Antigen و بعمل عملية الـ Separation، أكيد
+
+257
+00:19:15,010 --> 00:19:18,390
+الـ Separation هتكون باتجاه، مثلا لو تخيلنا هيك
+
+258
+00:19:18,390 --> 00:19:22,250
+أفقي على الصفحة أو على الصورة هذه، هتكون باتجاه
+
+259
+00:19:22,250 --> 00:19:26,670
+أفقي، مظبوط؟ فلقيت فصلت الـ Antigens، بعد ما خلصت
+
+260
+00:19:26,670 --> 00:19:30,830
+فصل باجي ع المرحلة التانية. Antigens are separated
+
+261
+00:19:30,830 --> 00:19:33,690
+on the basis of electrophoretic mobility. فصلت
+
+262
+00:19:33,690 --> 00:19:37,890
+الانتجنات، Antibody is placed in shell cut in the
+
+263
+00:19:37,890 --> 00:19:41,860
+agar. في عندي مكان فتحة في القدار بحط فيه الـ
+
+264
+00:19:41,860 --> 00:19:45,280
+Antibody. طيب، هلّق الـ Antibody كيف يتحرك؟ أكيد
+
+265
+00:19:45,280 --> 00:19:49,860
+هيتحرك باتجاه الـ Antigen، باتجاه عمودي على الرسمة،
+
+266
+00:19:49,860 --> 00:19:54,540
+صح؟ فبالتالي، بدي أغير اتجاه التيار الكهربائي، بدل
+
+267
+00:19:54,540 --> 00:19:59,220
+مكان أفقي حيسير باتجاه عمودي بحيث أنه يوصل الـ
+
+268
+00:19:59,220 --> 00:20:03,390
+Antibody للـ Antigen. الآن هيتحرك الـ Antibody لغاية
+
+269
+00:20:03,390 --> 00:20:07,450
+ما يوصل للـ Antigen، وإذا كان فيه Antigen خاص بالـ
+
+270
+00:20:07,450 --> 00:20:11,910
+Antibody هيعطيني line of precipitation. الـ second
+
+271
+00:20:11,910 --> 00:20:14,990
+separation is run at right angle to the first
+
+272
+00:20:14,990 --> 00:20:18,610
+الأولى بزاوية قائمة على الثانية، عملية الفصل أو
+
+273
+00:20:18,610 --> 00:20:23,650
+عملية الـ migration which drives the antigen into
+
+274
+00:20:23,650 --> 00:20:29,030
+the antiserum containing shell. هنا بوصل الـ
+
+275
+00:20:29,030 --> 00:20:33,710
+Antiserum مع الـ Antigen، باستخدامها هيكون عندي
+
+276
+00:20:33,710 --> 00:20:38,890
+precipitation peak أو يعني دوائر أو arc، دليل على
+
+277
+00:20:38,890 --> 00:20:41,550
+الـ precipitation. the area under the peak is
+
+278
+00:20:41,550 --> 00:20:45,130
+related to the concentration of Antigen. المسافة
+
+279
+00:20:45,130 --> 00:20:47,630
+تحت الـ peak اللي اتكونت بتعبر عن الـ
+
+280
+00:20:47,630 --> 00:20:49,910
+concentration للـ Antigen. هذا الكلام هنفهمه في
+
+281
+00:20:49,910 --> 00:20:54,150
+الشرايح اللي بعدها، تطلعوا
+
+282
+00:20:54,150 --> 00:20:59,410
+معايا حلقات. هي الـ Antigen انفصل لأكثر من Antigen
+
+283
+00:20:59,410 --> 00:21:03,030
+تمام، لأكثر من الـ Fraction، بعد هيك أنا حطيت الـ
+
+284
+00:21:03,030 --> 00:21:06,330
+Antibody، بدي أكشف عن وجود الـ Antibody، يكون أكثر
+
+285
+00:21:06,330 --> 00:21:08,790
+من Antibody، يعني mixed share من Antibodies عشان
+
+286
+00:21:08,790 --> 00:21:13,510
+أستدل على وجود بعض البروتينات، ع سبيل المثال، هيظهر
+
+287
+00:21:13,510 --> 00:21:18,410
+عندي Arc، هلاقيت كل ما مكان المسافة ما بين الـ Antigen
+
+288
+00:21:18,410 --> 00:21:21,710
+المكان اللي فصل فيه و الـ Arc هذه أكبر، كل ما مكان
+
+289
+00:21:21,710 --> 00:21:25,770
+تركيز الـ Antigen، لأنه محتاج يقطع مسافة أطول عشان
+
+290
+00:21:25,770 --> 00:21:31,770
+يوصل للـ equivalence line فيه.
+
+291
+00:21:31,770 --> 00:21:35,150
+هنا صورة، اطلع معايا، حطينا الـ antigen sample
+
+292
+00:21:35,150 --> 00:21:40,390
+فصلناها، هو هذا نفسه يعني بس صورة تانية، فصلناها هو
+
+293
+00:21:40,390 --> 00:21:45,090
+فعليا مش هشوفه لأنه مش هيكون مصبوغ، بعد ما بنفصلها
+
+294
+00:21:45,090 --> 00:21:48,410
+بنحط الـ antibody، بعد ما نحط الـ antibody بنمشي
+
+295
+00:21:48,410 --> 00:21:52,510
+التيار الكهربائي بالتجاه المعاكس، فهيظهر عندي الـ
+
+296
+00:21:52,510 --> 00:21:55,970
+precipitation line بهذا الشكل، الـ lines هذه
+
+297
+00:21:55,970 --> 00:22:00,130
+المسافة بينها وبين الانتجن بتدل على تركيز الانتجن.
+
+298
+00:22:00,130 --> 00:22:03,430
+هاي
+
+299
+00:22:03,430 --> 00:22:08,370
+كمان صورة تانية لإله، هاي يعني هذه الصورة يعني هنا
+
+300
+00:22:08,370 --> 00:22:11,930
+تخيل عندنا control، الـ control فصلنا من خلاله
+
+301
+00:22:11,930 --> 00:22:16,650
+الانتجنات الموجودة مثلا immunoglobulin مع قلبه من
+
+302
+00:22:16,650 --> 00:22:20,910
+and so on. هنا عند الـ patient sample، وحطينا الـ
+
+303
+00:22:20,910 --> 00:22:25,650
+Antibody وخلّينا الـ Antibody يمشي، هنلاقي ثواني
+
+304
+00:22:25,650 --> 00:22:31,810
+عندي Arcs بهذا الشكل، يعني برضه صور لنفس التطبيق
+
+305
+00:22:31,810 --> 00:22:39,550
+لنفس النوع من الـ Electrophoresis. نيجي
+
+306
+00:22:39,550 --> 00:22:43,390
+للنوع الثاني اللي هو Rocket Immunoelectrophoresis.
+
+307
+00:22:43,390 --> 00:22:48,870
+Rocket Immunoelectrophoresis هو شبيه جدا بالـ
+
+308
+00:22:48,870 --> 00:22:53,950
+Radial Immune Diffusion. بجيب الـ Agarose أو الجل
+
+309
+00:22:53,950 --> 00:22:57,890
+بحط فيه الـ Antibody، فاكرينه الـ Radial كان الـ
+
+310
+00:22:57,890 --> 00:23:01,870
+Antibody incorporated in جل يكون في داخل الجل، بعد
+
+311
+00:23:01,870 --> 00:23:05,650
+هيك بحط الـ Antigen في wells و بحط electrical
+
+312
+00:23:05,650 --> 00:23:11,110
+current، بسمح للـ Antigen يتحرك في اتجاه معين، طبعا
+
+313
+00:23:11,510 --> 00:23:15,010
+حيظل الـ Antigen ماشي لغاية ما يوصل لتخفيف معين
+
+314
+00:23:15,010 --> 00:23:18,970
+يتناسب مع تركيز الـ Antibody الموجود في الجل ويعمل
+
+315
+00:23:18,970 --> 00:23:25,790
+عندي precipitation line أو precipitation band.
+
+316
+00:23:25,790 --> 00:23:28,650
+height of precipitation band related to the
+
+317
+00:23:28,650 --> 00:23:31,710
+concentration of antigen. طبعا يعتبر أسرع من الـ
+
+318
+00:23:31,710 --> 00:23:34,230
+Radial Immune Diffusion. خليني أشوفه بالصور، بنفهمها
+
+319
+00:23:34,230 --> 00:23:41,700
+أكثر. تطلعوا معايا، هي الجل الـ Gel هذا موجود بقلبه الـ
+
+320
+00:23:41,700 --> 00:23:45,420
+Antibody، أنا بحط العينة، العينات بتاعتي و بمشي
+
+321
+00:23:45,420 --> 00:23:52,160
+التيار الكهربائي بحيث أنه الـ Gel، بحيث أنه الـ
+
+322
+00:23:52,160 --> 00:23:56,680
+Antigen يمشي في اتجاه معين، طبعا هنلاحظ أنه وصل الـ
+
+323
+00:23:56,680 --> 00:23:59,640
+precipitation لحد معين، وقف. كل ما الـ
+
+324
+00:23:59,640 --> 00:24:02,400
+precipitation أعلى، كل ما تركيز الـ Antigen هنا
+
+325
+00:24:02,400 --> 00:24:07,660
+أكثر، تمام؟ إذن هو سموه على فكرة Rocket لأنه عامل
+
+326
+00:24:07,660 --> 00:24:11,540
+زي الصاروخ شكله. عمل الـ precipitation arc زي قوس من
+
+327
+00:24:11,540 --> 00:24:15,140
+الـ precipitation. شايفين كيف؟ هك لو لاحظنا هذا أقل
+
+328
+00:24:15,140 --> 00:24:18,680
+واحد في التركيز، هذا أكثر، أكثر، كل ما اتجهنا هيك
+
+329
+00:24:18,680 --> 00:24:22,400
+هيزيد التركيز في الـ antigen في الـ wells اللي عندي.
+
+330
+00:24:22,400 --> 00:24:32,120
+هنا Rocket Immunoelectrophoresis. طيب
+
+331
+00:24:32,120 --> 00:24:35,440
+نيجي للنوع الثالث اللي هو counter
+
+332
+00:24:35,440 --> 00:24:39,010
+immunoelectrophoresis. هذا النوع من الـ
+
+333
+00:24:39,010 --> 00:24:44,290
+Electrophoresis بنستخدمه لما يكون الـ Antigens و
+
+334
+00:24:44,290 --> 00:24:49,870
+الـ Antibodies لهم شحنات مختلفة، بحيث يعني هو طبعا
+
+335
+00:24:49,870 --> 00:24:52,490
+أنا اللي بتحكم بالشحنة من خلال الـ Buffer اللي
+
+336
+00:24:52,490 --> 00:24:55,910
+بحطه، يعني بجيب Antigen و Antibody و Buffer.
+
+337
+00:24:55,910 --> 00:25:01,050
+بحيث أنه الـ Buffer عند بيئة معينة، واحد الـ
+
+338
+00:25:01,050 --> 00:25:04,450
+Antibody مثلا موجب، والتاني سالب، ماهو اللي بيصير؟
+
+339
+00:25:04,840 --> 00:25:08,400
+Reactions occur between migrating antigens and
+
+340
+00:25:08,400 --> 00:25:11,740
+antibodies during electrophoresis. Antigen and
+
+341
+00:25:11,740 --> 00:25:14,600
+antibody migrate toward each other by
+
+342
+00:25:14,600 --> 00:25:18,020
+electrophoresis. هيعملوا migration في اتجاه بعض
+
+343
+00:25:18,020 --> 00:25:23,620
+يعني لو أنا إجيت على هذه الأجراز، حطيت هنا فتحات
+
+344
+00:25:23,620 --> 00:25:26,600
+حطيت فيها الـ Antigen، و هنا فتحات حطيت فيها الـ
+
+345
+00:25:26,600 --> 00:25:31,540
+Antibody، طبعا ومشيت تيار كهربائي، واحد فيهم مثلا
+
+346
+00:25:31,540 --> 00:25:37,880
+الـ Antibody عندي هنا هيكون سالب شحنته عند pH معينة
+
+347
+00:25:37,880 --> 00:25:41,320
+ويمشي في اتجاه الـ cathode، والـ antigen موجب ويمشي
+
+348
+00:25:41,320 --> 00:25:44,160
+في اتجاه الـ anode، عند الـ equivalence zone
+
+349
+00:25:44,160 --> 00:25:48,300
+هيعملوا precipitation line، فده qualitative يعني
+
+350
+00:25:48,300 --> 00:25:51,080
+بقولّي إذا كان في antigen، إذا كان مثلا بدور على
+
+351
+00:25:51,080 --> 00:25:54,280
+antigen، إذا كان الـ antigen موجود ولا لأ، نفس
+
+352
+00:25:54,280 --> 00:25:58,320
+الأشياء هذه، فهذه ما عملوش precipitation line، معنى
+
+353
+00:25:58,320 --> 00:26:02,780
+الكلام إن العينة negative، تمام هيك؟ طيب، used only
+
+354
+00:26:02,780 --> 00:26:06,360
+when antigen and antibody have opposite charges.
+
+355
+00:26:06,360 --> 00:26:10,280
+لما يكون لهم شحنات مختلفة. pairs of wells are
+
+356
+00:26:10,280 --> 00:26:14,280
+bunched in agarose gels, in which antigen is
+
+357
+00:26:14,280 --> 00:26:17,400
+placed in one well of each pair and antibody in
+
+358
+00:26:17,400 --> 00:26:20,740
+the other. بحطه، بحط قباله الـ antibody بتاعه.
+
+359
+00:26:20,740 --> 00:26:24,980
+Following electrophoresis, precipitate lines will
+
+360
+00:26:24,980 --> 00:26:30,790
+be visible between the wells of a pair of wells of
+
+361
+00:26:30,790 --> 00:26:34,530
+matching specificity. يعني بينهم هيظهر عندي خط زي
+
+362
+00:26:34,530 --> 00:26:37,850
+ما قلنا، بدل على وجود الـ antigen أو الـ antibody
+
+363
+00:26:37,850 --> 00:26:42,250
+اللي بدور عليه. طبعا يعتبر qualitative test، يعتبر
+
+364
+00:26:42,250 --> 00:26:46,530
+فحص qualitative. its major advantage is its speed, يعني
+
+365
+00:26:46,530 --> 00:26:51,610
+هو يعتبر من الفحصات السريعة، وبتعطيني نتيجة يعني
+
+366
+00:26:51,610 --> 00:26:57,330
+بوقت قصير. هذا اسمه counter electrophoresis. إذا هو
+
+367
+00:26:57,330 --> 00:27:00,670
+يعتبر زي ما قلنا Two-dimensional Electrophoresis،
+
+368
+00:27:00,670 --> 00:27:07,390
+لأن الشحنات اللي هدول بيمشوا باتجاهات مختلفة، الـ
+
+369
+00:27:07,390 --> 00:27:12,490
+Antigen والـ Antibody. نيجي
+
+370
+00:27:12,490 --> 00:27:17,010
+لهذا النوع اللي هو النوع الآخر، الـ Immunofixation
+
+371
+00:27:17,010 --> 00:27:22,090
+Electrophoresis. هذا عبارة عن Electrophoresis، أول
+
+372
+00:27:22,090 --> 00:27:24,890
+شيء بعمل، بعدين بعمل Immune precipitation، يعني أول
+
+373
+00:27:24,890 --> 00:27:29,270
+شيء بفصل، بعدين بضيف الـ Antibody. this technique may
+
+374
+00:27:29,270 --> 00:27:32,590
+be used to identify and characterize serum or
+
+375
+00:27:32,590 --> 00:27:34,910
+urine proteins. يعني في عندي بعض الـ abnormal
+
+376
+00:27:34,910 --> 00:27:40,010
+بروتينات، بدي أتأكد من وجودها أو عدمها. هنا إيش اللي
+
+377
+00:27:40,010 --> 00:27:43,830
+بيصير؟ proteins of sample are first separated by
+
+378
+00:27:43,830 --> 00:27:47,490
+electrophoresis.  بفصل عادي بدون
+
+379
+00:27:47,490 --> 00:27:51,750
+ما أستخدم أي antibodies. تمام، بعد ما أخلص
+
+380
+00:27:51,750 --> 00:27:56,160
+separation، بحط على الـ Medium monospecific
+
+381
+00:27:56,160 --> 00:28:00,700
+antiserum reactive with specific protein antigen.
+
+382
+00:28:00,700 --> 00:28:04,000
+يعني أنا مثلا بدور على أنتجين معين، بروح بجيب
+
+383
+00:28:04,000 --> 00:28:06,880
+أنتيسيرم لهذا أو antibody لهذا، لبروتين أو الـ
+
+384
+00:28:06,880 --> 00:28:10,600
+Antigen. طبعا if the antigen is present, a
+
+385
+00:28:10,600 --> 00:28:13,280
+characteristic immunoprecipitation band will be
+
+386
+00:28:13,280 --> 00:28:17,640
+formed. لو كان الـ Antigen موجود، هيعمل في مكان ما
+
+387
+00:28:17,640 --> 00:28:18,980
+هو فاصل، هيعمل
+
+388
+00:28:24,240 --> 00:28:28,920
+طبعا هذه healthy control، أعتبر هذه negative يعني
+
+389
+00:28:28,920 --> 00:28:32,720
+ما ظهر عندي أي abnormal protein في هذه المناطق، لكن
+
+390
+00:28:32,720 --> 00:28:39,080
+هنا ظهر عندي band عند الكابا IGG، إذا هذا عنده
+
+391
+00:28:39,080 --> 00:28:45,340
+بارابروتين كابا من نوع الـ IGG antibodies.
+
+392
+00:28:52,230 --> 00:28:55,650
+This test is frequently ordered to identify
+
+393
+00:28:55,650 --> 00:28:58,890
+monoclonal proteins. بعض أنواع الـ monoclonal
+
+394
+00:28:58,890 --> 00:29:01,810
+البروتينات اللي ممكن تكون موجودة في الـ serum أو في
+
+395
+00:29:01,810 --> 00:29:04,950
+الـ urine. may be done on urine or serum depending
+
+396
+00:29:04,950 --> 00:29:09,010
+upon what the doctor suspects. الـ multiple myeloma طبعا
+
+397
+00:29:09,010 --> 00:29:11,630
+زي ما احنا عارفين في الـ myeloma بتطلع مجموعة كثيرة
+
+398
+00:29:11,630 --> 00:29:14,830
+من الـ specific proteins وممكن يصير لها excretion
+
+399
+00:29:14,830 --> 00:29:17,890
+في الـ urine، فبالتالي أنا ممكن أكشف عنها من خلال
+
+400
+00:29:17,890 --> 00:29:18,610
+هذا النوع.
+
+401
+00:29:21,580 --> 00:29:26,100
+نيجي لبعض مصادر الخطأ في الـ Electrophoresis، الـ
+
+402
+00:29:26,100 --> 00:29:31,020
+Current، يبقى الـ Direction له غلط، ال
\ No newline at end of file
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/V_Ub9yWovLk_raw.json b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/V_Ub9yWovLk_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..259480f07ad340d14ceb9ca594456cb66b6266ce
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/V_Ub9yWovLk_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 4796, "start": 20.32, "end": 47.96, "text": "طبعاً كل الكلام اللي حكيناه كان بتناول الـ precipitation لما بيحدث في liquid media وكيف ممكن نقرأه بالتربيدومتري أو بالنفلومتري وكل الأشياء اللي حكيناها إلها علاقة بالـ liquid media نيجي للـ precipitation in gel يعني زي ما صار ال precipitation في liquid media ممكن يصير في gel media precipitation in gel immune", "tokens": [9566, 3555, 3615, 995, 14111, 28242, 2423, 28820, 10943, 13672, 1829, 11331, 4117, 1829, 8315, 3224, 25961, 39894, 8315, 12610, 2423, 39184, 37662, 5296, 15042, 4724, 1829, 24401, 12984, 8978, 6553, 3021, 4032, 4117, 33911, 3714, 43020, 8717, 4587, 2288, 10721, 3224, 20666, 2655, 2288, 21292, 3215, 20498, 2655, 16572, 34051, 20666, 1863, 5172, 1211, 20498, 2655, 16572, 4032, 28820, 16247, 8592, 1829, 16606, 13672, 1829, 11331, 4117, 1829, 8315, 11296, 11933, 1211, 11296, 11203, 995, 28671, 20666, 39184, 6553, 3021, 8717, 1829, 7435, 1829, 24976, 39184, 37662, 294, 4087, 37495, 22653, 30767, 1829, 19446, 20328, 9640, 2423, 37662, 8978, 6553, 3021, 3714, 43020, 7251, 9381, 13546, 8978, 4087, 3021, 37662, 294, 4087, 11992], "avg_logprob": -0.16086957195530768, "compression_ratio": 1.9574468085106382, "no_speech_prob": 5.364418029785156e-07, "words": [{"start": 20.32, "end": 21.12, "word": "طبعاً", "probability": 0.8115234375}, {"start": 21.12, "end": 21.26, "word": " كل", "probability": 0.94775390625}, {"start": 21.26, "end": 21.68, "word": " الكلام", "probability": 0.8780924479166666}, {"start": 21.68, "end": 21.82, "word": " اللي", "probability": 0.89892578125}, {"start": 21.82, "end": 22.38, "word": " حكيناه", "probability": 0.919140625}, {"start": 22.38, "end": 22.62, "word": " كان", "probability": 0.94287109375}, {"start": 22.62, "end": 23.24, "word": " بتناول", "probability": 0.8147786458333334}, {"start": 23.24, "end": 23.5, "word": " الـ", "probability": 0.716552734375}, {"start": 23.5, "end": 23.86, "word": " precipitation", "probability": 0.375732421875}, {"start": 23.86, "end": 24.58, "word": " لما", "probability": 0.919677734375}, {"start": 24.58, "end": 25.1, "word": " بيحدث", "probability": 0.9183349609375}, {"start": 25.1, "end": 25.24, "word": " في", "probability": 0.91015625}, {"start": 25.24, "end": 25.62, "word": " liquid", "probability": 0.65478515625}, {"start": 25.62, "end": 26.02, "word": " media", "probability": 0.6328125}, {"start": 26.02, "end": 26.82, "word": " وكيف", "probability": 0.9420572916666666}, {"start": 26.82, "end": 27.04, "word": " ممكن", "probability": 0.96044921875}, {"start": 27.04, "end": 27.5, "word": " نقرأه", "probability": 0.86416015625}, {"start": 27.5, "end": 28.34, "word": " بالتربيدومتري", "probability": 0.79681396484375}, {"start": 28.34, "end": 28.52, "word": " أو", "probability": 0.9287109375}, {"start": 28.52, "end": 29.22, "word": " بالنفلومتري", "probability": 0.8662109375}, {"start": 29.22, "end": 29.56, "word": " وكل", "probability": 0.906005859375}, {"start": 29.56, "end": 29.96, "word": " الأشياء", "probability": 0.995849609375}, {"start": 29.96, "end": 30.12, "word": " اللي", "probability": 0.986572265625}, {"start": 30.12, "end": 30.74, "word": " حكيناها", "probability": 0.94951171875}, {"start": 30.74, "end": 31.34, "word": " إلها", "probability": 0.6321207682291666}, {"start": 31.34, "end": 31.78, "word": " علاقة", "probability": 0.9895833333333334}, {"start": 31.78, "end": 32.22, "word": " بالـ", "probability": 0.84716796875}, {"start": 32.22, "end": 32.46, "word": " liquid", "probability": 0.71923828125}, {"start": 32.46, "end": 32.84, "word": " media", "probability": 0.94775390625}, {"start": 32.84, "end": 34.76, "word": " نيجي", "probability": 0.9320068359375}, {"start": 34.76, "end": 35.06, "word": " للـ", "probability": 0.46630859375}, {"start": 35.06, "end": 35.42, "word": " precipitation", "probability": 0.9580078125}, {"start": 35.42, "end": 35.98, "word": " in", "probability": 0.95458984375}, {"start": 35.98, "end": 36.2, "word": " gel", "probability": 0.8408203125}, {"start": 36.2, "end": 36.7, "word": " يعني", "probability": 0.9150390625}, {"start": 36.7, "end": 36.92, "word": " زي", "probability": 0.986083984375}, {"start": 36.92, "end": 37.06, "word": " ما", "probability": 0.97412109375}, {"start": 37.06, "end": 37.34, "word": " صار", "probability": 0.948974609375}, {"start": 37.34, "end": 37.46, "word": " ال", "probability": 0.97900390625}, {"start": 37.46, "end": 37.88, "word": " precipitation", "probability": 0.80224609375}, {"start": 37.88, "end": 38.48, "word": " في", "probability": 0.9765625}, {"start": 38.48, "end": 38.9, "word": " liquid", "probability": 0.92626953125}, {"start": 38.9, "end": 39.4, "word": " media", "probability": 0.95654296875}, {"start": 39.4, "end": 39.98, "word": " ممكن", "probability": 0.98779296875}, {"start": 39.98, "end": 40.5, "word": " يصير", "probability": 0.9230143229166666}, {"start": 40.5, "end": 40.94, "word": " في", "probability": 0.98681640625}, {"start": 40.94, "end": 41.5, "word": " gel", "probability": 0.875}, {"start": 41.5, "end": 42.38, "word": " media", "probability": 0.89794921875}, {"start": 42.38, "end": 45.02, "word": " precipitation", "probability": 0.89404296875}, {"start": 45.02, "end": 46.36, "word": " in", "probability": 0.96630859375}, {"start": 46.36, "end": 47.02, "word": " gel", "probability": 0.94873046875}, {"start": 47.02, "end": 47.96, "word": " immune", "probability": 0.599609375}], "temperature": 1.0}, {"id": 2, "seek": 7831, "start": 48.62, "end": 78.32, "text": "Precipitate can form not only in solution but also in an agar matrix يعني لو أنا استخدمت agar matrix حطيت الـ Antigen و الـ Antibody في اتجاه بعض اقبل بعض هتلاقي أنه هيصير diffusion ما بين الـ Antigen و الـ Antibody و يوصلوا لمرحلة معينة أو لخط معين عند الالتقاء هيكونوا precipitation line هيكونوا خط من الـ precipitation when Antigen and Antibody diffuse towards one another in agar", "tokens": [47, 3326, 79, 8086, 393, 1254, 406, 787, 294, 3827, 457, 611, 294, 364, 623, 289, 8141, 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"end": 50.2, "word": " form", "probability": 0.947265625}, {"start": 50.2, "end": 50.5, "word": " not", "probability": 0.93017578125}, {"start": 50.5, "end": 50.9, "word": " only", "probability": 0.94140625}, {"start": 50.9, "end": 51.1, "word": " in", "probability": 0.96533203125}, {"start": 51.1, "end": 51.68, "word": " solution", "probability": 0.9169921875}, {"start": 51.68, "end": 51.94, "word": " but", "probability": 0.58935546875}, {"start": 51.94, "end": 52.36, "word": " also", "probability": 0.83740234375}, {"start": 52.36, "end": 52.56, "word": " in", "probability": 0.96875}, {"start": 52.56, "end": 52.76, "word": " an", "probability": 0.84765625}, {"start": 52.76, "end": 53.16, "word": " agar", "probability": 0.9052734375}, {"start": 53.16, "end": 53.76, "word": " matrix", "probability": 0.95166015625}, {"start": 53.76, "end": 54.48, "word": " يعني", "probability": 0.925048828125}, {"start": 54.48, "end": 54.72, "word": " لو", "probability": 0.9580078125}, {"start": 54.72, "end": 55.02, "word": " أنا", "probability": 0.79150390625}, {"start": 55.02, "end": 55.7, "word": " استخدمت", "probability": 0.9764404296875}, {"start": 55.7, "end": 56.08, "word": " agar", "probability": 0.956787109375}, {"start": 56.08, "end": 56.72, "word": " matrix", "probability": 0.97216796875}, {"start": 56.72, "end": 57.5, "word": " حطيت", "probability": 0.9391276041666666}, {"start": 57.5, "end": 57.72, "word": " الـ", "probability": 0.7269287109375}, {"start": 57.72, "end": 58.06, "word": " Antigen", "probability": 0.6802978515625}, {"start": 58.06, "end": 58.2, "word": " و", "probability": 0.6298828125}, {"start": 58.2, "end": 58.38, "word": " الـ", "probability": 0.793701171875}, {"start": 58.38, "end": 58.8, "word": " Antibody", "probability": 0.9152018229166666}, {"start": 58.8, "end": 58.98, "word": " في", "probability": 0.72802734375}, {"start": 58.98, "end": 59.36, "word": " اتجاه", "probability": 0.9571533203125}, {"start": 59.36, "end": 59.84, "word": " بعض", "probability": 0.97998046875}, {"start": 59.84, "end": 60.62, "word": " اقبل", "probability": 0.6322428385416666}, {"start": 60.62, "end": 61.06, "word": " بعض", "probability": 0.993408203125}, {"start": 61.06, "end": 61.9, "word": " هتلاقي", "probability": 0.956298828125}, {"start": 61.9, "end": 62.24, "word": " أنه", "probability": 0.6829833984375}, {"start": 62.24, "end": 62.8, "word": " هيصير", "probability": 0.8240559895833334}, {"start": 62.8, "end": 63.32, "word": " diffusion", "probability": 0.83447265625}, {"start": 63.32, "end": 63.64, "word": " ما", "probability": 0.89697265625}, {"start": 63.64, "end": 63.84, "word": " بين", "probability": 0.98583984375}, {"start": 63.84, "end": 64.08, "word": " الـ", "probability": 0.837158203125}, {"start": 64.08, "end": 64.42, "word": " Antigen", "probability": 0.954833984375}, {"start": 64.42, "end": 64.56, "word": " و", "probability": 0.96630859375}, {"start": 64.56, "end": 64.76, "word": " الـ", "probability": 0.923828125}, {"start": 64.76, "end": 65.54, "word": " Antibody", "probability": 0.97119140625}, {"start": 65.54, "end": 66.12, "word": " و", "probability": 0.96875}, {"start": 66.12, "end": 66.6, "word": " يوصلوا", "probability": 0.8985595703125}, {"start": 66.6, "end": 67.06, "word": " لمرحلة", "probability": 0.8892822265625}, {"start": 67.06, "end": 67.52, "word": " معينة", "probability": 0.9881184895833334}, {"start": 67.52, "end": 67.66, "word": " أو", "probability": 0.86474609375}, {"start": 67.66, "end": 67.98, "word": " لخط", "probability": 0.9599609375}, {"start": 67.98, "end": 68.4, "word": " معين", "probability": 0.997802734375}, {"start": 68.4, "end": 68.66, "word": " عند", "probability": 0.9912109375}, {"start": 68.66, "end": 69.36, "word": " الالتقاء", "probability": 0.903515625}, {"start": 69.36, "end": 70.28, "word": " هيكونوا", "probability": 0.9127604166666666}, {"start": 70.28, "end": 70.68, "word": " precipitation", "probability": 0.6826171875}, {"start": 70.68, "end": 71.54, "word": " 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77.26, "end": 77.64, "word": " another", "probability": 0.9345703125}, {"start": 77.64, "end": 77.88, "word": " in", "probability": 0.9609375}, {"start": 77.88, "end": 78.32, "word": " agar", "probability": 0.90966796875}], "temperature": 1.0}, {"id": 3, "seek": 10661, "start": 78.79, "end": 106.61, "text": "or when antibody is incorporated يعني هذا الخيار الأول اللي أنا شرحته الخيار الثاني أحيانا أنا بكون دامجة أو خالطة الـ antibody بالجل نفسه بالجل ال matrix تمام و بحط الانتجن هنا برضه هيظهر عندي visible line of precipitation as in precipitation reaction in liquid نفس الكلام اللي حكيناه في ال liquid ال precipitation line هذا أو ال visible precipitation بيصير في ال equivalence zone", "tokens": [284, 562, 34507, 307, 21654, 37495, 22653, 23758, 33962, 1829, 9640, 16247, 12610, 13672, 1829, 41850, 13412, 2288, 33753, 3224, 33962, 1829, 9640, 6024, 104, 7649, 1829, 5551, 5016, 1829, 7649, 995, 41850, 4724, 30544, 11778, 10943, 7435, 3660, 34051, 16490, 6027, 9566, 3660, 2423, 39184, 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"probability": 0.98828125}, {"start": 696.88, "end": 697.12, "word": " عند", "probability": 0.98486328125}, {"start": 697.12, "end": 697.26, "word": " الـ", "probability": 0.88427734375}, {"start": 697.26, "end": 697.44, "word": " line", "probability": 0.923828125}, {"start": 697.44, "end": 697.64, "word": " of", "probability": 0.9775390625}, {"start": 697.64, "end": 698.24, "word": " precipitation", "probability": 0.98095703125}, {"start": 698.24, "end": 699.06, "word": " عاليمين", "probability": 0.82452392578125}, {"start": 699.06, "end": 699.26, "word": " في", "probability": 0.95849609375}, {"start": 699.26, "end": 699.74, "word": " antigen", "probability": 0.7159423828125}, {"start": 699.74, "end": 700.18, "word": " axis", "probability": 0.84326171875}], "temperature": 1.0}, {"id": 25, "seek": 72062, "start": 700.4, "end": 720.62, "text": "وعالشمال في عندي Antibody Excess تمام؟ as equivalence is reached a visible line of precipitation اللي هو بنسمي precipitant line هذا الـ External Gel Diffusion مابنقدرش نعمله ك quantitative test بنعمل ك qualitative test عشان نشوف درجة إتشابه", "tokens": [45367, 6027, 8592, 2304, 6027, 8978, 18871, 16254, 5130, 897, 843, 2111, 780, 46811, 10943, 22807, 382, 9052, 655, 307, 6488, 257, 8974, 1622, 295, 37662, 13672, 1829, 31439, 44945, 38251, 1829, 23354, 270, 394, 1622, 23758, 2423, 39184, 48277, 16142, 413, 3661, 5704, 3714, 16758, 1863, 28543, 2288, 8592, 8717, 25957, 43761, 9122, 27778, 1500, 44945, 25957, 1211, 9122, 31312, 1500, 6225, 8592, 7649, 8717, 8592, 38688, 11778, 47341, 3660, 11933, 2655, 8592, 16758, 3224], "avg_logprob": -0.25649349875264355, "compression_ratio": 1.4144144144144144, "no_speech_prob": 9.357929229736328e-06, "words": [{"start": 700.4, "end": 701.28, "word": "وعالشمال", "probability": 0.7994140625}, {"start": 701.28, "end": 701.48, "word": " في", "probability": 0.67626953125}, {"start": 701.48, "end": 701.76, "word": " عندي", "probability": 0.7347412109375}, {"start": 701.76, "end": 702.4, "word": " 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"probability": 0.966552734375}, {"start": 708.28, "end": 708.4, "word": " هو", "probability": 0.970703125}, {"start": 708.4, "end": 709.02, "word": " بنسمي", "probability": 0.9156901041666666}, {"start": 709.02, "end": 709.88, "word": " precipitant", "probability": 0.474853515625}, {"start": 709.88, "end": 710.3, "word": " line", "probability": 0.935546875}, {"start": 710.3, "end": 711.02, "word": " هذا", "probability": 0.72607421875}, {"start": 711.02, "end": 711.16, "word": " الـ", "probability": 0.618408203125}, {"start": 711.16, "end": 711.58, "word": " External", "probability": 0.2060546875}, {"start": 711.58, "end": 711.92, "word": " Gel", "probability": 0.74609375}, {"start": 711.92, "end": 712.58, "word": " Diffusion", "probability": 0.8987630208333334}, {"start": 712.58, "end": 713.8, "word": " مابنقدرش", "probability": 0.866943359375}, {"start": 713.8, "end": 714.36, "word": " نعمله", "probability": 0.9850260416666666}, {"start": 714.36, "end": 714.58, "word": " ك", 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"probability": 0.827392578125}, {"start": 900.25, "end": 900.67, "word": " اتنين", "probability": 0.8983154296875}, {"start": 900.67, "end": 901.79, "word": " بيشبه", "probability": 0.93828125}, {"start": 901.79, "end": 902.83, "word": " الانتجن", "probability": 0.97431640625}, {"start": 902.83, "end": 903.29, "word": " واحد", "probability": 0.993896484375}, {"start": 903.29, "end": 903.83, "word": " لكن", "probability": 0.94189453125}, {"start": 903.83, "end": 904.19, "word": " مش", "probability": 0.97607421875}, {"start": 904.19, "end": 904.77, "word": " مشترك", "probability": 0.912109375}, {"start": 904.77, "end": 905.17, "word": " معاه", "probability": 0.979736328125}, {"start": 905.17, "end": 905.29, "word": " في", "probability": 0.98388671875}, {"start": 905.29, "end": 905.49, "word": " كل", "probability": 0.98486328125}, {"start": 905.49, "end": 905.61, "word": " ال", "probability": 0.970703125}, {"start": 905.61, "end": 906.11, "word": " Epitopes", "probability": 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كأنه لتو إبيتوبز تمام؟ وسمّى الـ Antigen اللي هنا XY نيح؟ فبطلع إتنين إما X أو Y يعني حيكون في واحد من إتنين إبيتوبز هدول إذا ظهر عندي نتوء على جهة واحدة تمام؟", "tokens": [3224, 2407, 34105, 6225, 8592, 7649, 1975, 5016, 8315, 6055, 30544, 31767, 13063, 3660, 5551, 4587, 25513, 5296, 28814, 1211, 8315, 12602, 39319, 8608, 2304, 11703, 7578, 2423, 39184, 5130, 897, 843, 13672, 1829, 34105, 48826, 37495, 22653, 9122, 33456, 3224, 5296, 2655, 2407, 11933, 21292, 2655, 37746, 11622, 46811, 10943, 22807, 46952, 2304, 11703, 7578, 2423, 39184, 5130, 3213, 13672, 1829, 34105, 48826, 8717, 1829, 5016, 22807, 6156, 3555, 9566, 1211, 3615, 11933, 2655, 1863, 9957, 11933, 15042, 1783, 34051, 398, 37495, 22653, 11331, 1829, 30544, 8978, 36764, 24401, 9154, 11933, 2655, 1863, 9957, 11933, 21292, 2655, 37746, 11622, 8032, 3215, 12610, 11933, 15730, 1357, 116, 3224, 2288, 18871, 16254, 8717, 2655, 2407, 38207, 15844, 10874, 3224, 3660, 36764, 24401, 3660, 46811, 10943, 22807], "avg_logprob": 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281, 264, 700, 16247, 12610, 7578, 4724, 11622, 995, 2407, 10632, 12174, 16373, 46007, 15844, 6024, 104, 7649, 10632, 6225, 42213, 10632, 27188, 36520, 34051, 6225, 42213, 10632, 2423, 39184, 17011, 597, 11754, 264, 2511, 3213, 666, 264, 2511, 6694, 449, 19273, 8720], "avg_logprob": -0.1744002468056149, "compression_ratio": 1.6007905138339922, "no_speech_prob": 1.1920928955078125e-07, "words": [{"start": 1200.87, "end": 1201.39, "word": "الأن", "probability": 0.680908203125}, {"start": 1201.39, "end": 1202.21, "word": " هيتحرك", "probability": 0.85186767578125}, {"start": 1202.21, "end": 1202.37, "word": " الـ", "probability": 0.96142578125}, {"start": 1202.37, "end": 1202.85, "word": " Antibody", "probability": 0.7603352864583334}, {"start": 1202.85, "end": 1203.39, "word": " لغاية", "probability": 0.986328125}, {"start": 1203.39, "end": 1203.51, "word": " ما", "probability": 0.98974609375}, {"start": 1203.51, "end": 1203.81, "word": " يوصل", "probability": 0.8673502604166666}, {"start": 1203.81, "end": 1204.03, "word": " للـ", "probability": 0.7685546875}, {"start": 1204.03, "end": 1204.45, "word": " Antigen", "probability": 0.893798828125}, {"start": 1204.45, "end": 1205.07, "word": " وإذا", "probability": 0.9542643229166666}, {"start": 1205.07, "end": 1205.41, "word": " كان", "probability": 0.99072265625}, {"start": 1205.41, "end": 1206.03, "word": " فيه", "probability": 0.765625}, {"start": 1206.03, "end": 1206.95, "word": " Antigen", "probability": 0.920654296875}, {"start": 1206.95, "end": 1207.25, "word": " خاص", "probability": 0.989013671875}, {"start": 1207.25, "end": 1207.45, "word": " بالـ", "probability": 0.976318359375}, {"start": 1207.45, "end": 1207.87, "word": " Antibody", "probability": 0.9593098958333334}, {"start": 1207.87, "end": 1208.69, "word": " هيعطيني", "probability": 0.82568359375}, {"start": 1208.69, "end": 1209.99, "word": " line", "probability": 0.42236328125}, {"start": 1209.99, "end": 1210.25, "word": " of", "probability": 0.9755859375}, {"start": 1210.25, "end": 1210.81, "word": " precipitation", "probability": 0.276123046875}, {"start": 1210.81, "end": 1211.69, "word": " الـ", "probability": 0.5125732421875}, {"start": 1211.69, "end": 1211.91, "word": " second", "probability": 0.5166015625}, {"start": 1211.91, "end": 1212.47, "word": " separation", "probability": 0.98046875}, {"start": 1212.47, "end": 1212.83, "word": " is", "probability": 0.8515625}, {"start": 1212.83, "end": 1213.05, "word": " run", "probability": 0.86865234375}, {"start": 1213.05, "end": 1213.29, "word": " at", "probability": 0.8837890625}, {"start": 1213.29, "end": 1213.63, "word": " right", "probability": 0.8740234375}, {"start": 1213.63, "end": 1214.03, "word": " angle", "probability": 0.84619140625}, {"start": 1214.03, "end": 1214.23, "word": " to", "probability": 0.921875}, {"start": 1214.23, "end": 1214.39, "word": " the", "probability": 0.90576171875}, {"start": 1214.39, "end": 1214.99, "word": " first", "probability": 0.91845703125}, {"start": 1214.99, "end": 1215.63, "word": " الأولى", "probability": 0.9392903645833334}, {"start": 1215.63, "end": 1216.23, "word": " بزاوية", "probability": 0.88388671875}, {"start": 1216.23, "end": 1216.59, "word": " قائمة", "probability": 0.9871419270833334}, {"start": 1216.59, "end": 1216.79, "word": " على", "probability": 0.9140625}, {"start": 1216.79, "end": 1217.21, "word": " الثانية", "probability": 0.84259033203125}, {"start": 1217.21, "end": 1217.57, "word": " عملية", "probability": 0.9397786458333334}, {"start": 1217.57, "end": 1218.43, "word": " الفصل", "probability": 0.960693359375}, {"start": 1218.43, "end": 1218.61, "word": " أو", "probability": 0.9638671875}, {"start": 1218.61, "end": 1219.05, "word": " عملية", "probability": 0.96533203125}, {"start": 1219.05, "end": 1219.63, "word": " الـ", "probability": 0.61767578125}, {"start": 1219.63, "end": 1220.15, "word": " migration", "probability": 0.83154296875}, {"start": 1220.15, "end": 1222.09, "word": " which", "probability": 0.83642578125}, {"start": 1222.09, "end": 1222.65, "word": " drives", "probability": 0.8681640625}, {"start": 1222.65, "end": 1222.89, "word": " the", "probability": 0.92431640625}, {"start": 1222.89, "end": 1223.35, "word": " antigen", "probability": 0.817138671875}, {"start": 1223.35, "end": 1223.65, "word": " into", "probability": 0.802734375}, {"start": 1223.65, "end": 1223.87, "word": " the", "probability": 0.91015625}, {"start": 1223.87, "end": 1224.51, "word": " antiserum", "probability": 0.9000651041666666}, {"start": 1224.51, "end": 1225.09, "word": " containing", "probability": 0.7041015625}, {"start": 1225.09, "end": 1225.43, "word": " shell", "probability": 0.798828125}], "temperature": 1.0}, {"id": 45, "seek": 125586, "start": 1226.27, "end": 1255.87, "text": "هنا بوصل الـ Antiserum مع الـ Antigen باستخدامها هيكون عندى precipitation peak أو يعني دوائر أو arc دليل على الـ precipitation the area under the peak is related to the concentration of Antigen المسافة تحت الـ peak اللي اتكونت بتتعبر عن الـ concentration للـ Antigen هذا الكلام هنفهمه في الشرايح اللي بعد تطلعوا معايا حلقات", "tokens": [3224, 8315, 4724, 2407, 36520, 2423, 39184, 5130, 6694, 449, 20449, 2423, 39184, 5130, 3213, 4724, 995, 14851, 9778, 3215, 10943, 11296, 39896, 30544, 43242, 7578, 37662, 10651, 34051, 37495, 22653, 11778, 2407, 16373, 2288, 34051, 10346, 11778, 20292, 1211, 15844, 2423, 39184, 37662, 264, 1859, 833, 264, 10651, 307, 4077, 281, 264, 9856, 295, 5130, 3213, 9673, 3794, 31845, 3660, 6055, 33753, 2423, 39184, 10651, 13672, 1829, 1975, 2655, 30544, 2655, 39894, 2655, 3615, 3555, 2288, 18871, 2423, 39184, 9856, 24976, 39184, 5130, 3213, 23758, 2423, 28820, 10943, 8032, 1863, 5172, 16095, 3224, 8978, 25124, 23557, 1829, 5016, 13672, 1829, 39182, 6055, 9566, 1211, 3615, 14407, 20449, 995, 25528, 11331, 1211, 4587, 9307], "avg_logprob": -0.15000000388725945, "compression_ratio": 1.7121771217712176, "no_speech_prob": 1.519918441772461e-05, "words": 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"probability": 0.8427734375}, {"start": 1234.81, "end": 1235.27, "word": " أو", "probability": 0.89208984375}, {"start": 1235.27, "end": 1236.03, "word": " يعني", "probability": 0.865234375}, {"start": 1236.03, "end": 1237.27, "word": " دوائر", "probability": 0.978759765625}, {"start": 1237.27, "end": 1237.63, "word": " أو", "probability": 0.92529296875}, {"start": 1237.63, "end": 1238.13, "word": " arc", "probability": 0.56884765625}, {"start": 1238.13, "end": 1238.77, "word": " دليل", "probability": 0.92822265625}, {"start": 1238.77, "end": 1238.89, "word": " على", "probability": 0.8388671875}, {"start": 1238.89, "end": 1239.01, "word": " الـ", "probability": 0.87109375}, {"start": 1239.01, "end": 1239.37, "word": " precipitation", "probability": 0.86328125}, {"start": 1239.37, "end": 1240.21, "word": " the", "probability": 0.1954345703125}, {"start": 1240.21, "end": 1240.51, "word": " area", "probability": 0.87646484375}, {"start": 1240.51, "end": 1240.79, "word": " under", "probability": 0.89892578125}, {"start": 1240.79, "end": 1241.07, "word": " the", "probability": 0.9326171875}, {"start": 1241.07, "end": 1241.31, "word": " peak", "probability": 0.90380859375}, {"start": 1241.31, "end": 1241.55, "word": " is", "probability": 0.9365234375}, {"start": 1241.55, "end": 1241.93, "word": " related", "probability": 0.982421875}, {"start": 1241.93, "end": 1242.15, "word": " to", "probability": 0.98046875}, {"start": 1242.15, "end": 1242.31, "word": " the", "probability": 0.88525390625}, {"start": 1242.31, "end": 1242.97, "word": " concentration", "probability": 0.88720703125}, {"start": 1242.97, "end": 1243.25, "word": " of", "probability": 0.98291015625}, {"start": 1243.25, "end": 1243.75, "word": " Antigen", "probability": 0.663330078125}, {"start": 1243.75, "end": 1245.13, "word": " المسافة", "probability": 0.9801025390625}, {"start": 1245.13, "end": 1245.41, "word": " تحت", "probability": 0.9921875}, {"start": 1245.41, "end": 1245.61, "word": " الـ", "probability": 0.74072265625}, {"start": 1245.61, "end": 1245.77, "word": " peak", "probability": 0.642578125}, {"start": 1245.77, "end": 1245.91, "word": " اللي", "probability": 0.791259765625}, {"start": 1245.91, "end": 1246.43, "word": " اتكونت", "probability": 0.91748046875}, {"start": 1246.43, "end": 1247.19, "word": " بتتعبر", "probability": 0.79716796875}, {"start": 1247.19, "end": 1247.39, "word": " عن", "probability": 0.97265625}, {"start": 1247.39, "end": 1247.63, "word": " الـ", "probability": 0.753173828125}, {"start": 1247.63, "end": 1248.15, "word": " concentration", "probability": 0.87451171875}, {"start": 1248.15, "end": 1248.39, "word": " للـ", "probability": 0.917236328125}, {"start": 1248.39, "end": 1248.71, "word": " Antigen", "probability": 0.920654296875}, {"start": 1248.71, "end": 1248.87, "word": " هذا", "probability": 0.364990234375}, {"start": 1248.87, "end": 1249.19, "word": " الكلام", "probability": 0.9724934895833334}, {"start": 1249.19, "end": 1249.73, "word": " هنفهمه", "probability": 0.95302734375}, {"start": 1249.73, "end": 1249.91, "word": " في", "probability": 0.95947265625}, {"start": 1249.91, "end": 1250.41, "word": " الشرايح", "probability": 0.8507080078125}, {"start": 1250.41, "end": 1250.55, "word": " اللي", "probability": 0.923095703125}, {"start": 1250.55, "end": 1250.79, "word": " بعد", "probability": 0.84619140625}, {"start": 1250.79, "end": 1254.15, "word": " تطلعوا", "probability": 0.87607421875}, {"start": 1254.15, "end": 1254.61, "word": " معايا", "probability": 0.9830729166666666}, {"start": 1254.61, "end": 1255.87, "word": " حلقات", "probability": 0.8785400390625}], "temperature": 1.0}, {"id": 46, "seek": 128271, "start": 1256.41, "end": 1282.71, "text": "هي الـ Antigen انفصل لأكتر من Antigen تمام لأكتر من الـ Fraction بعد هيك أنا حطيت الـ Antibody بدي أكشف عن وجود الـ Antibody يكون أكتر من Antibody يعني mixed share من Antibodies عشان أستدل على وجود بعض البروتينات ع سبيل المثال فهيظهر عندي Arc هلاقيت كل مكان المسافة ما بين الـ Antigen المكان اللي فصل فيه و الـ Arc هذه أكتر كل مكان تركيز الـ Antigen", "tokens": [3224, 1829, 2423, 39184, 5130, 3213, 16472, 5172, 36520, 5296, 10721, 4117, 2655, 2288, 9154, 5130, 3213, 46811, 10943, 5296, 10721, 4117, 2655, 2288, 9154, 2423, 39184, 1526, 2894, 39182, 39896, 4117, 41850, 11331, 9566, 36081, 2423, 39184, 5130, 897, 843, 4724, 16254, 5551, 4117, 8592, 5172, 18871, 49610, 23328, 2423, 39184, 5130, 897, 843, 7251, 30544, 5551, 4117, 2655, 2288, 9154, 5130, 897, 843, 37495, 22653, 7467, 2073, 9154, 5130, 897, 6087, 6225, 8592, 7649, 5551, 14851, 3215, 1211, 15844, 49610, 23328, 45030, 11242, 2423, 26890, 35473, 9957, 9307, 6225, 8608, 21292, 1211, 9673, 12984, 6027, 6156, 3224, 1829, 19913, 3224, 2288, 18871, 16254, 21727, 8032, 15040, 4587, 36081, 28242, 3714, 41361, 9673, 3794, 31845, 3660, 19446, 49374, 2423, 39184, 5130, 3213, 9673, 41361, 13672, 1829, 6156, 36520, 8978, 3224, 4032, 2423, 39184, 21727, 29538, 5551, 4117, 2655, 2288, 28242, 3714, 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control ال control فصلنا من خلاله الانتجنات الموجودة مثلا immunoglobulin مع قلبه من and so on هنا عند ال patient sample", "tokens": [6027, 39184, 37662, 1622, 39627, 15730, 25124, 28820, 2423, 39184, 3876, 29538, 9673, 3794, 31845, 3660, 49374, 11296, 46599, 9957, 2423, 7649, 2655, 7435, 1863, 39894, 3215, 1211, 15844, 6055, 31747, 1829, 11622, 2423, 7649, 2655, 7435, 1863, 8032, 47302, 9122, 2304, 7649, 20328, 13063, 3660, 6055, 7649, 10632, 5296, 28814, 43761, 8032, 47302, 37495, 22653, 29538, 31767, 13063, 3660, 37495, 22653, 34105, 6055, 9778, 26895, 43242, 8315, 1969, 2423, 1969, 6156, 36520, 8315, 9154, 16490, 1211, 6027, 3224, 2423, 7649, 2655, 7435, 8315, 2655, 9673, 29245, 23328, 3660, 50113, 15040, 13154, 45841, 12176, 259, 20449, 12174, 46152, 3224, 9154, 293, 370, 322, 34105, 43242, 2423, 4537, 6889], "avg_logprob": -0.17359518567356494, "compression_ratio": 1.7658730158730158, "no_speech_prob": 0.00019025802612304688, "words": [{"start": 1312.15, "end": 1312.51, "word": 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{"start": 1327.39, "end": 1327.93, "word": " الصورة", "probability": 0.99560546875}, {"start": 1327.93, "end": 1328.19, "word": " يعني", "probability": 0.6871337890625}, {"start": 1328.19, "end": 1328.37, "word": " هنا", "probability": 0.83984375}, {"start": 1328.37, "end": 1328.71, "word": " تخيل", "probability": 0.9342447916666666}, {"start": 1328.71, "end": 1329.01, "word": " عندنا", "probability": 0.6253662109375}, {"start": 1329.01, "end": 1329.57, "word": " control", "probability": 0.72412109375}, {"start": 1329.57, "end": 1330.21, "word": " ال", "probability": 0.9169921875}, {"start": 1330.21, "end": 1330.63, "word": " control", "probability": 0.58642578125}, {"start": 1330.63, "end": 1331.15, "word": " فصلنا", "probability": 0.97607421875}, {"start": 1331.15, "end": 1331.33, "word": " من", "probability": 0.9990234375}, {"start": 1331.33, "end": 1331.93, "word": " خلاله", "probability": 0.9949951171875}, {"start": 1331.93, "end": 1333.09, "word": " الانتجنات", "probability": 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advantage", "probability": 0.8876953125}, {"start": 1605.27, "end": 1605.71, "word": " its", "probability": 0.468994140625}, {"start": 1605.71, "end": 1606.19, "word": " speed", "probability": 0.9287109375}, {"start": 1606.19, "end": 1606.53, "word": " يعني", "probability": 0.950927734375}, {"start": 1606.53, "end": 1606.77, "word": " هو", "probability": 0.9736328125}, {"start": 1606.77, "end": 1607.39, "word": " يعتبر", "probability": 0.9737955729166666}, {"start": 1607.39, "end": 1607.57, "word": " من", "probability": 0.9951171875}, {"start": 1607.57, "end": 1608.15, "word": " الفحصات", "probability": 0.9591064453125}, {"start": 1608.15, "end": 1608.69, "word": " السريعة", "probability": 0.9319661458333334}, {"start": 1608.69, "end": 1609.45, "word": " وبتعطيني", "probability": 0.8256429036458334}, {"start": 1609.45, "end": 1610.35, "word": " نتيجة", "probability": 0.99072265625}, {"start": 1610.35, "end": 1611.61, "word": " يعني", "probability": 0.939208984375}, {"start": 1611.61, "end": 1612.05, "word": " بوقت", "probability": 0.9793294270833334}, {"start": 1612.05, "end": 1612.81, "word": " قصير", "probability": 0.998046875}, {"start": 1612.81, "end": 1614.37, "word": " هذا", "probability": 0.802734375}, {"start": 1614.37, "end": 1614.73, "word": " اسمه", "probability": 0.9420572916666666}, {"start": 1614.73, "end": 1615.21, "word": " counter", "probability": 0.61572265625}, {"start": 1615.21, "end": 1616.23, "word": " electrophoresis", "probability": 0.864990234375}], "temperature": 1.0}, {"id": 59, "seek": 164553, "start": 1616.61, "end": 1645.53, "text": "إذا هو يعتبر زي ما قلنا Two-dimensional Electrophoresis لأن الشحناء اللي هدول بيمشوا باتجاهات مختلفة الـ Antigen والـ Antibody نيجي لهذا النوع اللي هو النوع الأخر الـ Immunofixation Electrophoresis هذا عبارة عن Electrophoresis أول إشي بعمل بعدين بعمل Immune precipitation يعني أول إشي بفصل", "tokens": [28814, 15730, 31439, 7251, 34268, 26890, 30767, 1829, 19446, 12174, 1211, 8315, 4453, 12, 18759, 12575, 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{"start": 1618.21, "end": 1618.39, "word": " زي", "probability": 0.738525390625}, {"start": 1618.39, "end": 1618.49, "word": " ما", "probability": 0.98583984375}, {"start": 1618.49, "end": 1618.75, "word": " قلنا", "probability": 0.8400065104166666}, {"start": 1618.75, "end": 1619.05, "word": " Two", "probability": 0.1551513671875}, {"start": 1619.05, "end": 1619.75, "word": "-dimensional", "probability": 0.7412109375}, {"start": 1619.75, "end": 1620.67, "word": " Electrophoresis", "probability": 0.8115234375}, {"start": 1620.67, "end": 1620.99, "word": " لأن", "probability": 0.837890625}, {"start": 1620.99, "end": 1622.87, "word": " الشحناء", "probability": 0.92138671875}, {"start": 1622.87, "end": 1623.03, "word": " اللي", "probability": 0.66064453125}, {"start": 1623.03, "end": 1623.45, "word": " هدول", "probability": 0.9256184895833334}, {"start": 1623.45, "end": 1623.97, "word": " بيمشوا", "probability": 0.8907470703125}, {"start": 1623.97, "end": 1624.63, "word": " باتجاهات", "probability": 0.946484375}, {"start": 1624.63, "end": 1625.79, "word": " مختلفة", "probability": 0.99560546875}, {"start": 1625.79, "end": 1627.39, "word": " الـ", "probability": 0.78857421875}, {"start": 1627.39, "end": 1627.67, "word": " Antigen", "probability": 0.77978515625}, {"start": 1627.67, "end": 1627.85, "word": " والـ", "probability": 0.6456298828125}, {"start": 1627.85, "end": 1628.31, "word": " Antibody", "probability": 0.88916015625}, {"start": 1628.31, "end": 1632.49, "word": " نيجي", "probability": 0.884765625}, {"start": 1632.49, "end": 1633.13, "word": " لهذا", "probability": 0.749267578125}, {"start": 1633.13, "end": 1633.53, "word": " النوع", "probability": 0.97265625}, {"start": 1633.53, "end": 1633.73, "word": " اللي", "probability": 0.96923828125}, {"start": 1633.73, "end": 1634.03, "word": " هو", "probability": 0.9931640625}, {"start": 1634.03, "end": 1634.51, "word": " النوع", "probability": 0.940673828125}, {"start": 1634.51, "end": 1635.01, "word": " الأخر", "probability": 0.8037109375}, {"start": 1635.01, "end": 1635.89, "word": " الـ", "probability": 0.717041015625}, {"start": 1635.89, "end": 1637.01, "word": " Immunofixation", "probability": 0.86435546875}, {"start": 1637.01, "end": 1638.13, "word": " Electrophoresis", "probability": 0.8988037109375}, {"start": 1638.13, "end": 1639.63, "word": " هذا", "probability": 0.63330078125}, {"start": 1639.63, "end": 1640.27, "word": " عبارة", "probability": 0.996826171875}, {"start": 1640.27, "end": 1640.73, "word": " عن", "probability": 0.994140625}, {"start": 1640.73, "end": 1641.91, "word": " Electrophoresis", "probability": 0.95166015625}, {"start": 1641.91, "end": 1642.09, "word": " أول", "probability": 0.929443359375}, {"start": 1642.09, "end": 1642.33, "word": " إشي", "probability": 0.8487955729166666}, {"start": 1642.33, "end": 1642.73, "word": " بعمل", "probability": 0.9130859375}, {"start": 1642.73, "end": 1643.13, "word": " بعدين", "probability": 0.75048828125}, {"start": 1643.13, "end": 1643.43, "word": " بعمل", "probability": 0.97900390625}, {"start": 1643.43, "end": 1643.79, "word": " Immune", "probability": 0.5712890625}, {"start": 1643.79, "end": 1644.27, "word": " precipitation", "probability": 0.44873046875}, {"start": 1644.27, "end": 1644.71, "word": " يعني", "probability": 0.904052734375}, {"start": 1644.71, "end": 1644.89, "word": " أول", "probability": 0.96630859375}, {"start": 1644.89, "end": 1645.11, "word": " إشي", "probability": 0.9890950520833334}, {"start": 1645.11, "end": 1645.53, "word": " بفصل", "probability": 0.8966471354166666}], "temperature": 1.0}, {"id": 60, "seek": 167369, "start": 1646.27, "end": 1673.69, "text": "بعدين بضيف الـ Antibody this technique may be used to identify and characterize serum or urine proteins يعني في عندى بعض ال abnormal بروتينات بدي أتكتب من وجودها أو عدمها هنا إيش اللي بيصير proteins of sample are first separated by electrophoresis قدراسي يعني أول إيش بفصل عادي بدون ما أستخدم أي antibodies تمام بعد ما أخلص 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"word": " بضيف", "probability": 0.8675130208333334}, {"start": 1647.05, "end": 1647.25, "word": " الـ", "probability": 0.849365234375}, {"start": 1647.25, "end": 1647.71, "word": " Antibody", "probability": 0.8069661458333334}, {"start": 1647.71, "end": 1648.43, "word": " this", "probability": 0.3447265625}, {"start": 1648.43, "end": 1648.97, "word": " technique", "probability": 0.9443359375}, {"start": 1648.97, "end": 1649.27, "word": " may", "probability": 0.78369140625}, {"start": 1649.27, "end": 1649.53, "word": " be", "probability": 0.95458984375}, {"start": 1649.53, "end": 1650.03, "word": " used", "probability": 0.91259765625}, {"start": 1650.03, "end": 1650.23, "word": " to", "probability": 0.9365234375}, {"start": 1650.23, "end": 1650.89, "word": " identify", "probability": 0.93359375}, {"start": 1650.89, "end": 1651.21, "word": " and", "probability": 0.9248046875}, {"start": 1651.21, "end": 1651.71, "word": " characterize", "probability": 0.8427734375}, {"start": 1651.71, 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1656.59, "word": " أتكتب", "probability": 0.63876953125}, {"start": 1656.59, "end": 1656.75, "word": " من", "probability": 0.9541015625}, {"start": 1656.75, "end": 1657.25, "word": " وجودها", "probability": 0.9910481770833334}, {"start": 1657.25, "end": 1657.41, "word": " أو", "probability": 0.89697265625}, {"start": 1657.41, "end": 1658.13, "word": " عدمها", "probability": 0.9319661458333334}, {"start": 1658.13, "end": 1659.63, "word": " هنا", "probability": 0.92333984375}, {"start": 1659.63, "end": 1659.91, "word": " إيش", "probability": 0.8001302083333334}, {"start": 1659.91, "end": 1660.01, "word": " اللي", "probability": 0.94873046875}, {"start": 1660.01, "end": 1660.45, "word": " بيصير", "probability": 0.799072265625}, {"start": 1660.45, "end": 1661.07, "word": " proteins", "probability": 0.556640625}, {"start": 1661.07, "end": 1661.45, "word": " of", "probability": 0.974609375}, {"start": 1661.45, "end": 1661.93, "word": " sample", "probability": 0.7685546875}, {"start": 1661.93, "end": 1662.31, "word": " are", "probability": 0.94970703125}, {"start": 1662.31, "end": 1662.81, "word": " first", "probability": 0.8828125}, {"start": 1662.81, "end": 1663.41, "word": " separated", "probability": 0.8994140625}, {"start": 1663.41, "end": 1663.83, "word": " by", "probability": 0.95556640625}, {"start": 1663.83, "end": 1664.77, "word": " electrophoresis", "probability": 0.9176025390625}, {"start": 1664.77, "end": 1665.81, "word": " قدراسي", "probability": 0.55125732421875}, {"start": 1665.81, "end": 1665.95, "word": " يعني", "probability": 0.87255859375}, {"start": 1665.95, "end": 1666.15, "word": " أول", "probability": 0.94775390625}, {"start": 1666.15, "end": 1666.29, "word": " إيش", "probability": 0.7047526041666666}, {"start": 1666.29, "end": 1666.71, "word": " بفصل", "probability": 0.9440104166666666}, {"start": 1666.71, "end": 1667.07, "word": " عادي", "probability": 0.9290364583333334}, {"start": 1667.07, "end": 1667.49, "word": " بدون", "probability": 0.9951171875}, {"start": 1667.49, "end": 1667.67, "word": " ما", "probability": 0.685546875}, {"start": 1667.67, "end": 1668.23, "word": " أستخدم", "probability": 0.9053955078125}, {"start": 1668.23, "end": 1668.49, "word": " أي", "probability": 0.8583984375}, {"start": 1668.49, "end": 1669.15, "word": " antibodies", "probability": 0.8349609375}, {"start": 1669.15, "end": 1670.07, "word": " تمام", "probability": 0.667724609375}, {"start": 1670.07, "end": 1671.21, "word": " بعد", "probability": 0.81396484375}, {"start": 1671.21, "end": 1671.35, "word": " ما", "probability": 0.9404296875}, {"start": 1671.35, "end": 1671.75, "word": " أخلص", "probability": 0.98291015625}, {"start": 1671.75, "end": 1672.35, "word": " separation", "probability": 0.86376953125}, {"start": 1672.35, "end": 1673.69, "word": " بحط", "probability": 0.9729817708333334}], "temperature": 1.0}, {"id": 61, "seek": 169898, "start": 1673.86, "end": 1698.98, "text": "على الـ Medium monospecific antiserum reactive with specific protein antigen يعني أنا مثلا بدور على أنتجن معين بروح بجيب أنتسيرم لهذا أو antibody لهذا لبروتين أو الـ Antigen طبعا if the antigen is present a characteristic immunoprecipitation band will be formed لو كان الـ Antigen موجود هيعمل في مكان ما هو فاصل هيعمل", "tokens": [3615, 23942, 2423, 39184, 38915, 1108, 329, 494, 22856, 2511, 6694, 449, 28897, 365, 2685, 7944, 2511, 3213, 37495, 22653, 41850, 50113, 15040, 47525, 13063, 15844, 5551, 29399, 7435, 1863, 20449, 9957, 4724, 32887, 5016, 4724, 7435, 1829, 3555, 5551, 29399, 3794, 13546, 2304, 46740, 15730, 34051, 34507, 46740, 15730, 5296, 26890, 35473, 9957, 34051, 2423, 39184, 5130, 3213, 23032, 3555, 3615, 995, 498, 264, 2511, 3213, 307, 1974, 257, 16282, 13154, 404, 3326, 79, 4614, 4116, 486, 312, 8693, 45164, 25961, 2423, 39184, 5130, 3213, 3714, 29245, 23328, 39896, 25957, 1211, 8978, 3714, 41361, 19446, 31439, 6156, 33546, 1211, 39896, 25957, 1211], "avg_logprob": -0.21018629850676426, "compression_ratio": 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{"start": 1690.6, "end": 1691.22, "word": " characteristic", "probability": 0.92333984375}, {"start": 1691.22, "end": 1692.46, "word": " immunoprecipitation", "probability": 0.90087890625}, {"start": 1692.46, "end": 1692.84, "word": " band", "probability": 0.81103515625}, {"start": 1692.84, "end": 1693.04, "word": " will", "probability": 0.8828125}, {"start": 1693.04, "end": 1693.28, "word": " be", "probability": 0.96337890625}, {"start": 1693.28, "end": 1693.68, "word": " formed", "probability": 0.9501953125}, {"start": 1693.68, "end": 1693.94, "word": " لو", "probability": 0.83642578125}, {"start": 1693.94, "end": 1694.2, "word": " كان", "probability": 0.9921875}, {"start": 1694.2, "end": 1694.36, "word": " الـ", "probability": 0.742919921875}, {"start": 1694.36, "end": 1694.66, "word": " Antigen", "probability": 0.841796875}, {"start": 1694.66, "end": 1695.26, "word": " موجود", "probability": 0.9884440104166666}, {"start": 1695.26, "end": 1696.06, "word": " هيعمل", "probability": 0.87548828125}, {"start": 1696.06, "end": 1696.22, "word": " في", "probability": 0.98876953125}, {"start": 1696.22, "end": 1696.7, "word": " مكان", "probability": 0.96484375}, {"start": 1696.7, "end": 1697.64, "word": " ما", "probability": 0.9775390625}, {"start": 1697.64, "end": 1697.84, "word": " هو", "probability": 0.98681640625}, {"start": 1697.84, "end": 1698.42, "word": " فاصل", "probability": 0.9803059895833334}, {"start": 1698.42, "end": 1698.98, "word": " هيعمل", "probability": 0.7587890625}], "temperature": 1.0}, {"id": 62, "seek": 172534, "start": 1704.24, "end": 1725.34, "text": "طبعاً هذه healthy control ابعتبرها negative يعني ماظهر عندي أي abnormal protein في هذه المناطق لكن هنا ظهر عندي band عند الكابا IGG إذا هذا عنده بارابروتين كابا من نوع ال IGG antibodies", "tokens": [9566, 3555, 3615, 995, 14111, 29538, 4627, 1969, 48127, 34268, 26890, 11296, 3671, 37495, 22653, 19446, 19913, 3224, 2288, 18871, 16254, 36632, 32847, 7944, 8978, 29538, 9673, 1863, 41193, 4587, 44381, 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"probability": 0.935546875}, {"start": 1709.4, "end": 1709.66, "word": " عندي", "probability": 0.7088623046875}, {"start": 1709.66, "end": 1709.84, "word": " أي", "probability": 0.765625}, {"start": 1709.84, "end": 1710.24, "word": " abnormal", "probability": 0.63671875}, {"start": 1710.24, "end": 1710.7, "word": " protein", "probability": 0.7939453125}, {"start": 1710.7, "end": 1710.92, "word": " في", "probability": 0.94091796875}, {"start": 1710.92, "end": 1711.14, "word": " هذه", "probability": 0.857421875}, {"start": 1711.14, "end": 1711.76, "word": " المناطق", "probability": 0.9881591796875}, {"start": 1711.76, "end": 1712.72, "word": " لكن", "probability": 0.931640625}, {"start": 1712.72, "end": 1713.24, "word": " هنا", "probability": 0.97802734375}, {"start": 1713.24, "end": 1714.0, "word": " ظهر", "probability": 0.9295654296875}, {"start": 1714.0, "end": 1714.28, "word": " عندي", "probability": 0.83837890625}, {"start": 1714.28, "end": 1714.64, "word": " band", "probability": 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3555, 3615, 995, 30767, 1829, 19446, 1975, 5016, 8315, 6225, 9640, 5172, 9957, 8978, 2423, 452, 338, 6440, 39894, 9566, 1211, 3615, 3714, 7435, 2304, 2407, 27884, 9122, 2655, 48923, 9154, 2423, 2685, 15577, 4032, 2304, 43020, 7251, 9381, 13546, 5296, 11296, 15058, 8978, 2423, 27638, 6156, 3555, 6027, 2655, 6027, 1829, 1975, 8315, 3714, 43020, 1975, 4117, 8592, 5172, 18871, 11296, 9154, 16490, 1211, 6027, 23758, 28239, 45367], "avg_logprob": -0.1486707038398999, "compression_ratio": 1.7053291536050157, "no_speech_prob": 4.887580871582031e-06, "words": [{"start": 1732.23, "end": 1732.79, "word": "التests", "probability": 0.4739583333333333}, {"start": 1732.79, "end": 1733.01, "word": " is", "probability": 0.6171875}, {"start": 1733.01, "end": 1733.63, "word": " frequently", "probability": 0.9521484375}, {"start": 1733.63, "end": 1734.17, "word": " ordered", "probability": 0.75927734375}, {"start": 1734.17, "end": 1734.45, "word": " to", "probability": 0.861328125}, {"start": 1734.45, 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{"start": 1749.15, "end": 1749.25, "word": " ما", "probability": 0.98681640625}, {"start": 1749.25, "end": 1749.43, "word": " احنا", "probability": 0.85546875}, {"start": 1749.43, "end": 1749.87, "word": " عارفين", "probability": 0.9876708984375}, {"start": 1749.87, "end": 1750.13, "word": " في", "probability": 0.92041015625}, {"start": 1750.13, "end": 1750.21, "word": " ال", "probability": 0.90625}, {"start": 1750.21, "end": 1750.53, "word": " myeloma", "probability": 0.89013671875}, {"start": 1750.53, "end": 1750.91, "word": " بتطلع", "probability": 0.958251953125}, {"start": 1750.91, "end": 1751.31, "word": " مجموعة", "probability": 0.9693359375}, {"start": 1751.31, "end": 1751.63, "word": " كتيرة", "probability": 0.8885091145833334}, {"start": 1751.63, "end": 1751.81, "word": " من", "probability": 0.9931640625}, {"start": 1751.81, "end": 1751.89, "word": " ال", "probability": 0.8818359375}, {"start": 1751.89, "end": 1752.25, "word": " specific", "probability": 0.90380859375}, {"start": 1752.25, "end": 1752.93, "word": " proteins", "probability": 0.95361328125}, {"start": 1752.93, "end": 1753.85, "word": " وممكن", "probability": 0.9280598958333334}, {"start": 1753.85, "end": 1754.11, "word": " يصير", "probability": 0.7032470703125}, {"start": 1754.11, "end": 1754.27, "word": " لها", "probability": 0.883056640625}, {"start": 1754.27, "end": 1754.83, "word": " execution", "probability": 0.96826171875}, {"start": 1754.83, "end": 1755.25, "word": " في", "probability": 0.97021484375}, {"start": 1755.25, "end": 1755.31, "word": " ال", "probability": 0.958984375}, {"start": 1755.31, "end": 1755.49, "word": " urine", "probability": 0.98974609375}, {"start": 1755.49, "end": 1755.97, "word": " فبالتالي", "probability": 0.97998046875}, {"start": 1755.97, "end": 1756.13, "word": " انا", "probability": 0.815673828125}, {"start": 1756.13, "end": 1756.37, "word": " ممكن", "probability": 0.994873046875}, {"start": 1756.37, "end": 1756.85, "word": " اكشف", "probability": 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diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/XBAwIl2C7qc_raw.json b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/XBAwIl2C7qc_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..65a3ec9d6ba8384c75450b50a12fda3c63005425
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/XBAwIl2C7qc_raw.json
@@ -0,0 +1 @@
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"text": "بعد مواجهة اللواز بشوية بتبدأ مشكلة المفاصل يعني ممكن يكون اتعافى من اللواز لكن ضلت أثارها، ضلت الـToxin بتاعتها الـAntibodies اللي اتطورت للـToxin ضلت موجودة في الجسم وهي اللي بتعمل الـ IgG هذا اللي اتكون أو الـAntibodies اللي اتكونت هي اللي هتعمل Cross Reaction مع الـAntigens بتاعة خلايا المفاصل مثلا وتعمل آلام شديدة", "tokens": [3555, 22488, 3714, 2407, 26108, 3224, 3660, 13672, 2407, 31377, 4724, 8592, 2407, 10632, 39894, 44510, 10721, 37893, 28820, 3660, 9673, 5172, 33546, 1211, 37495, 22653, 3714, 43020, 7251, 30544, 1975, 2655, 3615, 31845, 7578, 9154, 13672, 2407, 31377, 44381, 48812, 1211, 2655, 5551, 12984, 9640, 11296, 12399, 48812, 1211, 2655, 2423, 39184, 51, 5230, 259, 39894, 995, 34268, 11296, 2423, 39184, 35807, 897, 6087, 13672, 1829, 1975, 2655, 9566, 13063, 2655, 24976, 39184, 51, 5230, 259, 48812, 1211, 2655, 3714, 29245, 23328, 3660, 8978, 25724, 38251, 37037, 1829, 13672, 1829, 39894, 25957, 1211, 2423, 39184, 19271, 38, 23758, 13672, 1829, 1975, 2655, 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months after the primary source of infection has eradicated يعني ممكن تظل الـ Antibody شهور بعد ما تنتهي المشكلة الأساسية يعني ممكن يكون مافيش بكتيريا خلاص يعني اتعافى المريض تماما أو حتى ممكن تكون يعني موجود بعض البكتيريا بس موجودة بشكل chronic في داخل اللوزتان", "tokens": [2278, 34507, 815, 312, 21896, 294, 264, 3390, 337, 3259, 420, 2493, 934, 264, 6194, 4009, 295, 11764, 575, 33078, 3587, 37495, 22653, 3714, 43020, 6055, 19913, 1211, 2423, 39184, 5130, 897, 843, 13412, 3224, 13063, 39182, 19446, 6055, 29399, 3224, 1829, 9673, 8592, 28820, 3660, 16247, 3794, 32277, 10632, 37495, 22653, 3714, 43020, 7251, 30544, 19446, 41185, 8592, 4724, 4117, 2655, 13546, 25528, 16490, 1211, 33546, 37495, 22653, 1975, 2655, 3615, 31845, 7578, 9673, 16572, 11242, 46811, 10943, 995, 34051, 11331, 49975, 3714, 43020, 6055, 30544, 37495, 22653, 3714, 29245, 23328, 45030, 11242, 29739, 4117, 2655, 13546, 25528, 4724, 3794, 3714, 29245, 23328, 3660, 4724, 8592, 28820, 14493, 8978, 11778, 47283, 1211, 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"probability": 0.9524739583333334}, {"start": 323.77, "end": 324.25, "word": " بكتيريا", "probability": 0.98369140625}, {"start": 324.25, "end": 324.57, "word": " خلاص", "probability": 0.8875325520833334}, {"start": 324.57, "end": 324.77, "word": " يعني", "probability": 0.8388671875}, {"start": 324.77, "end": 325.21, "word": " اتعافى", "probability": 0.92783203125}, {"start": 325.21, "end": 325.57, "word": " المريض", "probability": 0.9514973958333334}, {"start": 325.57, "end": 326.13, "word": " تماما", "probability": 0.9900716145833334}, {"start": 326.13, "end": 326.67, "word": " أو", "probability": 0.90625}, {"start": 326.67, "end": 326.97, "word": " حتى", "probability": 0.929931640625}, {"start": 326.97, "end": 327.39, "word": " ممكن", "probability": 0.989013671875}, {"start": 327.39, "end": 327.97, "word": " تكون", "probability": 0.953125}, {"start": 327.97, "end": 328.29, "word": " يعني", "probability": 0.982421875}, {"start": 328.29, "end": 329.11, "word": " موجود", "probability": 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3 أسابيع من الـ infection فرصة أني ألاقي الـ Antistreptolysin O positive من 90 إلى 95% شهرين من 70 إلى 75%", "tokens": [2407, 2304, 8592, 6225, 10943, 37977, 37893, 995, 28820, 44381, 2423, 39184, 4657, 2655, 2407, 4117, 3794, 9957, 5933, 37279, 25708, 2655, 11296, 39894, 19913, 1211, 8978, 2423, 39184, 3390, 6156, 2655, 2288, 9307, 23032, 2407, 26895, 3660, 39182, 8717, 11296, 10632, 9673, 8592, 28820, 3660, 37495, 22653, 39182, 19446, 1975, 2655, 3615, 31845, 7578, 8032, 2655, 19913, 1211, 9673, 8592, 28820, 3660, 3714, 29245, 23328, 3660, 23032, 1829, 3555, 12399, 34105, 4724, 39648, 4117, 39182, 805, 5551, 3794, 16758, 40228, 9154, 2423, 39184, 11764, 6156, 2288, 9381, 3660, 14739, 1829, 5551, 15040, 38436, 2423, 39184, 5130, 468, 265, 662, 16453, 19767, 422, 3353, 9154, 4289, 30731, 13420, 4, 13412, 3224, 2288, 9957, 9154, 5285, 30731, 9562, 4], "avg_logprob": -0.18264180572093033, "compression_ratio": 1.5433962264150944, "no_speech_prob": 3.2186508178710938e-06, "words": 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344.74, "word": " هنا", "probability": 0.98974609375}, {"start": 344.74, "end": 345.36, "word": " بقولك", "probability": 0.9405924479166666}, {"start": 345.36, "end": 346.04, "word": " بعد", "probability": 0.9365234375}, {"start": 346.04, "end": 346.32, "word": " 3", "probability": 0.57958984375}, {"start": 346.32, "end": 346.88, "word": " أسابيع", "probability": 0.9254150390625}, {"start": 346.88, "end": 347.08, "word": " من", "probability": 0.99658203125}, {"start": 347.08, "end": 347.22, "word": " الـ", "probability": 0.768798828125}, {"start": 347.22, "end": 347.6, "word": " infection", "probability": 0.685546875}, {"start": 347.6, "end": 348.28, "word": " فرصة", "probability": 0.9910888671875}, {"start": 348.28, "end": 348.58, "word": " أني", "probability": 0.6385498046875}, {"start": 348.58, "end": 349.14, "word": " ألاقي", "probability": 0.931640625}, {"start": 349.14, "end": 349.48, "word": " الـ", "probability": 0.974609375}, {"start": 349.48, "end": 350.54, "word": " 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الـ titer 2 بقول ال ASOT 2 في 200 بساوي 400", "tokens": [39237, 10943, 1017, 23032, 1211, 34268, 3671, 16490, 5172, 33911, 502, 5296, 39184, 568, 23032, 1211, 34268, 3353, 16070, 39184, 1017, 18871, 25708, 9122, 33911, 4724, 4117, 2655, 3555, 28239, 31371, 7435, 3660, 22807, 4724, 11242, 25513, 2423, 39184, 256, 1681, 8978, 2331, 37495, 22653, 23032, 1211, 34268, 20449, 995, 25528, 43242, 2423, 39184, 256, 1681, 568, 4724, 4117, 2655, 3555, 8592, 2423, 39184, 256, 1681, 568, 4724, 39648, 2423, 7469, 5068, 568, 8978, 2331, 4724, 3794, 995, 45865, 8423], "avg_logprob": -0.23360339211828915, "compression_ratio": 1.560693641618497, "no_speech_prob": 1.0251998901367188e-05, "words": [{"start": 705.37, "end": 705.97, "word": "تمام", "probability": 0.71875}, {"start": 705.97, "end": 706.37, "word": " 4", "probability": 0.285400390625}, {"start": 706.37, "end": 706.79, "word": " طلعت", "probability": 0.951171875}, {"start": 706.79, "end": 707.23, "word": " negative", "probability": 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"end": 753.57, "text": "تمام؟ إذاً هيك بتنكتب النتيجة مابكتبش الـ Titer 2 لأ بكتب الـ Concentration للـ ASOT أو الـ ASOT Titer 400 إذا طلعت مثلا الـ Titer 4 بكتب 4 في 200 يعني 800 and so on هيك بتنكتب نتيجتها مابتنكتبش Titer 2 و 4 و 8 ليش؟ لأنه هي أساساً احنا افترضنا إنه في أقل من 200", "tokens": [39237, 10943, 22807, 11933, 15730, 14111, 39896, 4117, 39894, 1863, 4117, 2655, 3555, 28239, 31371, 7435, 3660, 3714, 16758, 4117, 2655, 3555, 8592, 2423, 39184, 314, 1681, 568, 5296, 10721, 4724, 4117, 2655, 3555, 2423, 39184, 2656, 2207, 2405, 24976, 39184, 7469, 5068, 34051, 2423, 39184, 7469, 5068, 314, 1681, 8423, 11933, 15730, 23032, 1211, 34268, 50113, 15040, 2423, 39184, 314, 1681, 1017, 4724, 4117, 2655, 3555, 1017, 8978, 2331, 37495, 22653, 13083, 293, 370, 322, 39896, 4117, 39894, 1863, 4117, 2655, 3555, 8717, 31371, 7435, 2655, 11296, 3714, 16758, 2655, 1863, 4117, 2655, 3555, 8592, 314, 1681, 568, 4032, 1017, 4032, 1649, 32239, 8592, 22807, 5296, 33456, 3224, 39896, 5551, 3794, 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"probability": 0.93994140625}, {"start": 744.61, "end": 744.89, "word": " on", "probability": 0.9599609375}, {"start": 744.89, "end": 745.19, "word": " هيك", "probability": 0.89697265625}, {"start": 745.19, "end": 745.73, "word": " بتنكتب", "probability": 0.982421875}, {"start": 745.73, "end": 746.25, "word": " نتيجتها", "probability": 0.97470703125}, {"start": 746.25, "end": 747.05, "word": " مابتنكتبش", "probability": 0.94525146484375}, {"start": 747.05, "end": 747.57, "word": " Titer", "probability": 0.763916015625}, {"start": 747.57, "end": 748.27, "word": " 2", "probability": 0.94189453125}, {"start": 748.27, "end": 748.45, "word": " و", "probability": 0.81494140625}, {"start": 748.45, "end": 748.77, "word": " 4", "probability": 0.78125}, {"start": 748.77, "end": 749.01, "word": " و", "probability": 0.52099609375}, {"start": 749.01, "end": 749.31, "word": " 8", "probability": 0.9248046875}, {"start": 749.31, "end": 749.83, "word": " ليش؟", "probability": 0.88037109375}, {"start": 749.83, "end": 750.19, "word": " لأنه", "probability": 0.75439453125}, {"start": 750.19, "end": 750.35, "word": " هي", "probability": 0.84521484375}, {"start": 750.35, "end": 751.33, "word": " أساساً", "probability": 0.9345703125}, {"start": 751.33, "end": 751.57, "word": " احنا", "probability": 0.84521484375}, {"start": 751.57, "end": 752.09, "word": " افترضنا", "probability": 0.97353515625}, {"start": 752.09, "end": 752.39, "word": " إنه", "probability": 0.74951171875}, {"start": 752.39, "end": 752.51, "word": " في", "probability": 0.97119140625}, {"start": 752.51, "end": 752.95, "word": " أقل", "probability": 0.8916015625}, {"start": 752.95, "end": 753.13, "word": " من", "probability": 0.99560546875}, {"start": 753.13, "end": 753.57, "word": " 200", "probability": 0.95751953125}], "temperature": 1.0}, {"id": 30, "seek": 78045, "start": 754.13, "end": 780.45, "text": "موجودة عند أي شخص Positive فبدي أضرب الـ 200 هذي اللي هي تحت الـ Positive Control في أي رقم هنا من الـ Titer وطلّع إليه الـ Interpretation The serum ASO Titer can be defined as the highest dilution showing a positive result The approximate ASO Titer present in the sample can be obtained by the following ASO Titer اللي هو الhighest dilution مضروب في 200", "tokens": [2304, 29245, 23328, 3660, 43242, 36632, 13412, 9778, 9381, 46326, 6156, 3555, 16254, 5551, 11242, 25513, 2423, 39184, 2331, 8032, 8848, 1829, 13672, 1829, 39896, 6055, 33753, 2423, 39184, 46326, 12912, 8978, 36632, 12602, 4587, 2304, 34105, 9154, 2423, 39184, 314, 1681, 4032, 9566, 1211, 11703, 3615, 11933, 20292, 3224, 2423, 39184, 5751, 6629, 399, 440, 32755, 7469, 46, 314, 1681, 393, 312, 7642, 382, 264, 6343, 11504, 1448, 4099, 257, 3353, 1874, 440, 30874, 7469, 46, 314, 1681, 1974, 294, 264, 6889, 393, 312, 14879, 538, 264, 3480, 7469, 46, 314, 1681, 13672, 1829, 31439, 2423, 21454, 377, 11504, 1448, 3714, 11242, 32887, 3555, 8978, 2331], "avg_logprob": -0.25535300760357466, "compression_ratio": 1.5516014234875444, "no_speech_prob": 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"probability": 0.9189453125}, {"start": 774.13, "end": 774.49, "word": " sample", "probability": 0.87744140625}, {"start": 774.49, "end": 774.79, "word": " can", "probability": 0.9443359375}, {"start": 774.79, "end": 774.97, "word": " be", "probability": 0.96630859375}, {"start": 774.97, "end": 775.49, "word": " obtained", "probability": 0.96044921875}, {"start": 775.49, "end": 775.83, "word": " by", "probability": 0.9833984375}, {"start": 775.83, "end": 776.05, "word": " the", "probability": 0.92822265625}, {"start": 776.05, "end": 776.39, "word": " following", "probability": 0.87109375}, {"start": 776.39, "end": 776.91, "word": " ASO", "probability": 0.983642578125}, {"start": 776.91, "end": 777.45, "word": " Titer", "probability": 0.88232421875}, {"start": 777.45, "end": 777.97, "word": " اللي", "probability": 0.86474609375}, {"start": 777.97, "end": 778.05, "word": " هو", "probability": 0.98828125}, {"start": 778.05, "end": 778.59, "word": " الhighest", "probability": 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793.71, "end": 793.93, "word": " اللي", "probability": 0.981689453125}, {"start": 793.93, "end": 794.51, "word": " شرحناه", "probability": 0.97734375}, {"start": 794.51, "end": 794.71, "word": " قبل", "probability": 0.991455078125}, {"start": 794.71, "end": 795.23, "word": " بشوية", "probability": 0.9085693359375}, {"start": 795.23, "end": 799.89, "word": " طيب", "probability": 0.9454752604166666}, {"start": 799.89, "end": 800.07, "word": " لو", "probability": 0.86376953125}, {"start": 800.07, "end": 800.45, "word": " طلعت", "probability": 0.990234375}, {"start": 800.45, "end": 801.01, "word": " النتيجة", "probability": 0.9678955078125}, {"start": 801.01, "end": 801.37, "word": " معايا", "probability": 0.9729817708333334}, {"start": 801.37, "end": 801.95, "word": " positive", "probability": 0.791015625}, {"start": 801.95, "end": 802.55, "word": " معنى", "probability": 0.8953450520833334}, {"start": 802.55, "end": 803.07, "word": " الكلام", "probability": 0.97314453125}, {"start": 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infection وهذه تعتبر complications لإلها elevated levels may indicate ارتفاع ال level ممكن يدل على active infection Striptococcal infection أو sore throat أو rheumatic fever أو scarlet fever يعني في هدول ممكن ألاقيها positive", "tokens": [2407, 9566, 3555, 3615, 995, 14111, 30767, 1829, 19446, 12174, 1211, 2655, 23275, 2304, 39896, 25961, 2655, 6055, 3215, 3615, 32640, 5296, 3555, 3615, 11242, 20390, 662, 905, 905, 9895, 11764, 26566, 37495, 22653, 39896, 20328, 9640, 8978, 20390, 662, 905, 905, 9895, 11764, 37037, 24192, 6055, 34268, 26890, 26566, 5296, 28814, 1211, 11296, 23457, 4358, 815, 13330, 1975, 43500, 5172, 45761, 2423, 1496, 3714, 43020, 7251, 3215, 1211, 15844, 4967, 11764, 20390, 662, 905, 905, 9895, 11764, 34051, 22468, 12394, 34051, 50100, 449, 2399, 18277, 34051, 10569, 2631, 18277, 37495, 22653, 8978, 8032, 3215, 12610, 3714, 43020, 5551, 15040, 38436, 11296, 3353], "avg_logprob": -0.17427883970622832, "compression_ratio": 1.6809338521400778, "no_speech_prob": 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970.44, "end": 970.66, "word": " الـ", "probability": 0.659912109375}, {"start": 970.66, "end": 970.88, "word": " contamination", "probability": 0.81787109375}, {"start": 970.88, "end": 971.82, "word": " للـ", "probability": 0.541259765625}, {"start": 971.82, "end": 972.14, "word": " slime", "probability": 0.73388671875}, {"start": 972.14, "end": 972.54, "word": " برضه", "probability": 0.8636067708333334}, {"start": 972.54, "end": 972.8, "word": " هذه", "probability": 0.58642578125}, {"start": 972.8, "end": 973.48, "word": " بتعطيني", "probability": 0.9015625}, {"start": 973.48, "end": 973.88, "word": " false", "probability": 0.65283203125}, {"start": 973.88, "end": 974.3, "word": " positive", "probability": 0.9130859375}, {"start": 974.3, "end": 975.08, "word": " result", "probability": 0.9287109375}, {"start": 975.08, "end": 976.1, "word": " تمام", "probability": 0.9228515625}, {"start": 976.1, "end": 977.36, "word": " هيك؟", "probability": 0.7197265625}, {"start": 977.36, "end": 978.08, "word": " هيك", "probability": 0.886962890625}, {"start": 978.08, "end": 978.36, "word": " بنكون", "probability": 0.916748046875}, {"start": 978.36, "end": 979.08, "word": " خلصنا", "probability": 0.9815673828125}, {"start": 979.08, "end": 979.6, "word": " ال", "probability": 0.9892578125}, {"start": 979.6, "end": 980.58, "word": " ASO", "probability": 0.7509765625}, {"start": 980.58, "end": 982.82, "word": " من", "probability": 0.97119140625}, {"start": 982.82, "end": 983.5, "word": " فحصات", "probability": 0.881591796875}, {"start": 983.5, "end": 983.66, "word": " ال", "probability": 0.96826171875}, {"start": 983.66, "end": 984.32, "word": " agglutination", "probability": 0.88623046875}, {"start": 984.32, "end": 984.68, "word": " وان", "probability": 0.655029296875}, {"start": 984.68, "end": 984.82, "word": " شاء", "probability": 0.937255859375}, {"start": 984.82, "end": 984.9, "word": " الله", "probability": 0.93359375}, {"start": 984.9, "end": 985.18, "word": " ربنا", "probability": 0.9454752604166666}, {"start": 985.18, "end": 985.54, "word": " ييسر", "probability": 0.8380126953125}, {"start": 985.54, "end": 985.92, "word": " الأمور", "probability": 0.9814453125}, {"start": 985.92, "end": 986.46, "word": " ونشتغلوا", "probability": 0.8433314732142857}, {"start": 986.46, "end": 986.86, "word": " عملية", "probability": 0.638671875}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 993.1175, "duration_after_vad": 964.1256250000018}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/dgRcKWVpf5Q_postprocess.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/dgRcKWVpf5Q_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..5c6c68ff5cf4688c583fa700f6f8793dc06a52cd
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/dgRcKWVpf5Q_postprocess.srt
@@ -0,0 +1,1468 @@
+1
+00:00:01,130 --> 00:00:05,030
+بسم الله الرحمن الرحيم إن شاء الله رب العالمين راح
+
+2
+00:00:05,030 --> 00:00:09,070
+ناخد مع بعض الجزئية التانية في التفاعلات الخاصة
+
+3
+00:00:09,070 --> 00:00:11,730
+بالمنع أو الأمثال اللي هي الـ precipitation
+
+4
+00:00:11,730 --> 00:00:14,670
+reaction طبعا إحنا خلصنا من ال agglutination
+
+5
+00:00:14,670 --> 00:00:19,670
+reactions و أخدنا ال applications بتاعتها راح ناخد
+
+6
+00:00:19,670 --> 00:00:25,110
+مع بعض الموضوع التاني ال precipitation تعتبر من
+
+7
+00:00:25,110 --> 00:00:29,250
+الفحوصات السيرولوجي البسيطةبحيث أن سلبو الـ
+
+8
+00:00:29,250 --> 00:00:32,430
+Antigen و الـ Antibody بتفاعلوا مع بعض و بيكونوا
+
+9
+00:00:32,430 --> 00:00:35,950
+lattice that develops into visible precipitates
+
+10
+00:00:35,950 --> 00:00:39,870
+يعني تفاعل الـ Antigen و الـ Antibody هنا الذائبين
+
+11
+00:00:39,870 --> 00:00:44,850
+بتحولوا لـ precipitates واضح ممكن أنا أشوفه و أحدد
+
+12
+00:00:44,850 --> 00:00:48,550
+إذا كان صاير فيه reaction ولا مش صاير أو care
+
+13
+00:00:48,550 --> 00:00:51,850
+based when Antigen and Antibody are present in
+
+14
+00:00:51,850 --> 00:00:55,970
+optimal proportion طبعا زي ما حكينا في ال
+
+15
+00:00:55,970 --> 00:00:59,890
+agglutinationلازم يكون في تكافؤ ما بين كمية الـ
+
+16
+00:00:59,890 --> 00:01:03,410
+Antigen و الـ Antibody عشان أنا أشوف ال reaction
+
+17
+00:01:03,410 --> 00:01:07,390
+بشكل واضح و يحصل فعليًا هذا ال reaction و زي ما
+
+18
+00:01:07,390 --> 00:01:10,750
+حكينا إنه في عندي منطقة بسميها equivalence zone
+
+19
+00:01:10,750 --> 00:01:15,310
+منطقة التكافؤ بيكون فيها التفاعل أفضل ما يكون
+
+20
+00:01:15,310 --> 00:01:19,270
+Antibodies that aggregate soluble antigen are
+
+21
+00:01:19,270 --> 00:01:23,190
+called precipitate الـ Antibodies المسؤولة عنهإنها
+
+22
+00:01:23,190 --> 00:01:26,850
+تعمل الـ precipitation للأنتجينات هذه بسميها
+
+23
+00:01:26,850 --> 00:01:31,150
+precipitation طبعاً في الـ agglutination سمناها
+
+24
+00:01:31,150 --> 00:01:33,950
+agglutinin اللي كانت بتعمل agglutination هنا ال
+
+25
+00:01:33,950 --> 00:01:37,090
+precipitation بسميها precipitation زي ما أنتوا
+
+26
+00:01:37,090 --> 00:01:42,050
+شايفين في تجمع الانتجن بشبك مع أكتر من antibody و
+
+27
+00:01:42,050 --> 00:01:44,950
+ال antibody كمان بشبك مع أكتر من انتجن فبالتالي
+
+28
+00:01:44,950 --> 00:01:47,830
+بتكون عندى lattice formation عند ال equivalence
+
+29
+00:01:47,830 --> 00:01:48,270
+zone
+
+30
+00:01:52,470 --> 00:01:58,050
+طيب هنا في عنا نقطة مهمة بقولك أنه الـ polyclonal
+
+31
+00:01:58,050 --> 00:02:01,470
+antibodies عندها القدرة على إنها تكون lettuce
+
+32
+00:02:01,470 --> 00:02:05,130
+بينما أو large aggregates بينما الـ monoclonal
+
+33
+00:02:05,130 --> 00:02:09,610
+antibody مش هتقدر تكون lettuce هتروحه هي شابكة مع
+
+34
+00:02:09,610 --> 00:02:14,530
+antigen واحدزي ما انتوا شايفين بالصورة وبالتالي مش
+
+35
+00:02:14,530 --> 00:02:17,750
+هتقدر تشبك مع بعض وتعمل عنده visible agglutination
+
+36
+00:02:17,750 --> 00:02:21,390
+هي الـ polyclonal antibody الـ antibody لأنه قادر
+
+37
+00:02:21,390 --> 00:02:25,110
+يرتبط بأكتر من إبتوب على أكتر من أنتجن قدر يعمل
+
+38
+00:02:25,110 --> 00:02:28,530
+lattice formation لكن الـ monoclonal antibody ما
+
+39
+00:02:28,530 --> 00:02:32,590
+بيقدر يرتبط غير مع إبتوب واحد على الانتجن فبالتالي
+
+40
+00:02:32,590 --> 00:02:37,410
+ما بيقدر يعمل visible agglutinationشغلة تانية الـ
+
+41
+00:02:37,410 --> 00:02:40,330
+precipitation occurs in two media عملية ال
+
+42
+00:02:40,330 --> 00:02:44,150
+precipitation ممكن تحصل في two media إما في liquid
+
+43
+00:02:44,150 --> 00:02:51,190
+media أو gel media نيجي
+
+44
+00:02:51,190 --> 00:02:57,550
+لل precipitation in liquid طيب
+
+45
+00:02:57,550 --> 00:03:00,590
+نيجي لل reaction أو ال precipitation reaction في
+
+46
+00:03:00,590 --> 00:03:04,270
+ال liquidالـ precipitation reaction ممكن يصير بالـ
+
+47
+00:03:04,270 --> 00:03:07,770
+liquid بحيث أن الـ antigen والـ antibody يتفاعلوا
+
+48
+00:03:07,770 --> 00:03:12,030
+إلى ما يكون في equivalence في تركيزهم ويعطوني
+
+49
+00:03:12,030 --> 00:03:17,750
+visible precipitation طيب هنا هو بده يدرس سلوك ال
+
+50
+00:03:17,750 --> 00:03:21,190
+precipitation في الـ liquid مع تغير تركيز ال
+
+51
+00:03:21,190 --> 00:03:24,970
+antibody كيف؟ بقولك بنعمل
+
+52
+00:03:27,260 --> 00:03:30,080
+بنعمل Serial Dilution من الـ Antigen أو الـ
+
+53
+00:03:30,080 --> 00:03:36,720
+Antibody وبنضيف عليهم Constant Volume من التاني
+
+54
+00:03:36,720 --> 00:03:38,720
+يعني أنا إذا عملت Serial Dilution من الـ Antigen
+
+55
+00:03:38,720 --> 00:03:42,180
+بضيف Constant Volume من الـ Antibody إذا عملت
+
+56
+00:03:42,180 --> 00:03:45,920
+Serial Dilution بضيف Constant Volume من الـ
+
+57
+00:03:45,920 --> 00:03:50,500
+Antigenزي اللي حكيناها اللي هو تحضير الـ Serial
+
+58
+00:03:50,500 --> 00:03:53,220
+Dilution في القنابيب يعني أنا بحضر Serial Dilution
+
+59
+00:03:53,220 --> 00:03:57,060
+وبدأ أشوف كيف تصرف الـ Precipitation وكيف ممكن
+
+60
+00:03:57,060 --> 00:04:00,000
+أشوف الـ Precipitation في هذه القنابيب مع الـ
+
+61
+00:04:00,000 --> 00:04:03,360
+Dilution اللي أنا عملته وبعد ما خلصت برسم علاقة
+
+62
+00:04:03,360 --> 00:04:07,640
+بيانية ما بين التركيز الـ Concentration اللي أنا
+
+63
+00:04:07,640 --> 00:04:11,140
+عملته أو الـ Dilution اللي أنا عملته ومع كمية الـ
+
+64
+00:04:11,140 --> 00:04:14,870
+Precipitation اللي اتكونت، هيطلع معايا curveبالشكل
+
+65
+00:04:14,870 --> 00:04:18,810
+التالي اللي هنشوفهها الانت طبعا زي ما احنا شايفين
+
+66
+00:04:18,810 --> 00:04:23,450
+القنابيب اللي حضر فيها الـ Serial Dilution هو حط
+
+67
+00:04:23,450 --> 00:04:26,770
+Fixed amount من الـ Antibody وغير تركيز الـ
+
+68
+00:04:26,770 --> 00:04:30,350
+Antigen بحيث انه القنابيب هذه فيها أعلى تركيز من
+
+69
+00:04:30,350 --> 00:04:33,710
+الـ Antigen وكل ما اتجهنا لهذا الاتجاه بيكون الـ
+
+70
+00:04:33,710 --> 00:04:38,700
+Antigen تركيزه أقلبدايةً، راح يكون في عندي تركيز
+
+71
+00:04:38,700 --> 00:04:42,060
+عالي للـ Antibodies في الأربع قنابيب الأولى مش شرط
+
+72
+00:04:42,060 --> 00:04:44,600
+الأربع، يعني ممكن تلاتة، ممكن تنتين، ممكن واحدة
+
+73
+00:04:44,600 --> 00:04:47,020
+ممكن مايظهرش أصلاً هذه المنطقة إن مافيش
+
+74
+00:04:47,020 --> 00:04:50,640
+precipitation يعني برجع للتركيز وتناسبها مع بعض
+
+75
+00:04:50,640 --> 00:04:54,700
+الآن، في أول أربع قنابيب ماظهر عنده precipitation
+
+76
+00:04:54,700 --> 00:04:58,580
+هذه المنطقة تبقى فيها كمية الـ Antibody عالية لأنه
+
+77
+00:04:58,580 --> 00:05:03,430
+تركيز الـ Antigen قليل بسميها الـ Bra zoneبعد هيك
+
+78
+00:05:03,430 --> 00:05:06,490
+بيصير في equivalence هنلاقي انه ظهر عندى
+
+79
+00:05:06,490 --> 00:05:09,590
+precipitate العينات الأولى هتكون negative بينما
+
+80
+00:05:09,590 --> 00:05:14,390
+هذه هتكون positive لغاية حد معين هيصير high
+
+81
+00:05:14,390 --> 00:05:18,130
+dilution للانتجن بعد هيك مش هيظهر عندى
+
+82
+00:05:18,130 --> 00:05:21,790
+agglutination في هذه المنطقة اللى بسميها bust zone
+
+83
+00:05:21,790 --> 00:05:26,130
+فبالتالي ال agglutination ال precipitation طبعا
+
+84
+00:05:26,130 --> 00:05:28,510
+والكلام نفسه على ال agglutination سواء قلت
+
+85
+00:05:28,510 --> 00:05:30,970
+agglutination أو precipitation الكلام بنطبق على
+
+86
+00:05:30,970 --> 00:05:34,050
+اتنانسواء الـ Agglutination أو الـ Precipitation
+
+87
+00:05:34,050 --> 00:05:36,890
+سيظهر في الـ Zone of Equivalence لو كان الـ
+
+88
+00:05:36,890 --> 00:05:43,290
+Antibody كميته عالية سيكون لدي Block للأنتجن بالـ
+
+89
+00:05:43,290 --> 00:05:46,250
+Antibody ومش هيعطيني Visible Agglutination نفس
+
+90
+00:05:46,250 --> 00:05:49,400
+الأشي لو كان الـ Antigen تركيزه عاليوهذا اللي احنا
+
+91
+00:05:49,400 --> 00:05:52,860
+بنشوفه في التفاعلات تحديد الـ Titer يعني أنتوا
+
+92
+00:05:52,860 --> 00:05:57,040
+بتلاحظوا أنه بداية بيبدأ معاكي Positive بعد هيك
+
+93
+00:05:57,040 --> 00:06:00,820
+بيبدأ يعطيكي Negative ليش بيعطيكي Negative؟ لأنه
+
+94
+00:06:00,820 --> 00:06:04,940
+انت خففتي الـ Antibody كتير وصار تركيز الـ Antigen
+
+95
+00:06:04,940 --> 00:06:08,620
+عالي فبالتالي عند حد معين هيبطل يعطيكي Positive
+
+96
+00:06:08,620 --> 00:06:11,820
+طيب هدول الأربع أو القنابيب اللي بالأول هي في الـ
+
+97
+00:06:11,820 --> 00:06:15,360
+Prozone هذه يا بنات احنا مش دامن بنشوفها يعني
+
+98
+00:06:15,360 --> 00:06:19,460
+تلقيا بيبقى تركيز الـ Antibody عالي جداوما بقدرش
+
+99
+00:06:19,460 --> 00:06:21,540
+من خلاله أشوف الـ precipitation أو الـ
+
+100
+00:06:21,540 --> 00:06:24,640
+agglutination وأحيانًا لأ ما بيتبين لأنه من
+
+101
+00:06:24,640 --> 00:06:27,660
+البداية ممكن احنا بدأنا ال reaction تبعنا من منطقة
+
+102
+00:06:27,660 --> 00:06:30,220
+ال equivalence وهذا اللي احنا بنلاحظه في ال
+
+103
+00:06:30,220 --> 00:06:32,780
+titration يعني احنا عادة في فحصات ال titration
+
+104
+00:06:32,780 --> 00:06:37,400
+نادر لما بيطلع معايا ال brozone عادة بتطلع معايا
+
+105
+00:06:37,400 --> 00:06:40,020
+ال equivalence zone بعد هيك بيزول ال agglutination
+
+106
+00:06:40,020 --> 00:06:42,240
+زي ما لاحظته بيبقى agglutination أو precipitation
+
+107
+00:06:42,240 --> 00:06:47,720
+بعد هيك بتصير تعتينة negativeيعني خدوا بالكم هذا
+
+108
+00:06:47,720 --> 00:06:50,920
+ال curve ممكن لاحظته لمرة تانية بأكد كنت أحيان
+
+109
+00:06:50,920 --> 00:06:53,840
+بقول precipitation أو agglutination لأنه بينطبق
+
+110
+00:06:53,840 --> 00:06:58,280
+على التنين هنا
+
+111
+00:06:58,280 --> 00:07:01,960
+بقولك لو كانت كمية ال antibody زيادة إيش اللي
+
+112
+00:07:01,960 --> 00:07:06,200
+هيصير؟زي ما انتم ملاحظين الـ Antibodies لأنه عددها
+
+113
+00:07:06,200 --> 00:07:09,000
+كتير كبير و الـ Antigen قليلة هتعمل Block للـ
+
+114
+00:07:09,000 --> 00:07:12,400
+Antigen فبالتالي مش هيقدر الـ Antigen يشبك مع أكتر
+
+115
+00:07:12,400 --> 00:07:14,740
+من Antibody هيشبك مع Antibody واحد يعني انتم
+
+116
+00:07:14,740 --> 00:07:18,300
+شايفين كيف الـ Antigen محوطا الـ Antibodies من كل
+
+117
+00:07:18,300 --> 00:07:22,460
+اتجاه فبالتالي مش قادر يعطيني Lattice Formation
+
+118
+00:07:22,460 --> 00:07:25,480
+لكن في الـ Zone of Equivalence تبقى فيه تكافؤ في
+
+119
+00:07:25,480 --> 00:07:28,920
+الكمية فبالتالي كل Antigen هتلاقي شابق مع أكتر من
+
+120
+00:07:28,920 --> 00:07:32,480
+Antibody وكل Antibody شابق مع أكتر من Antigenبيكون
+
+121
+00:07:32,480 --> 00:07:36,980
+عندك Status في منطقة زيادة الـ Antigen هتبقى كمية
+
+122
+00:07:36,980 --> 00:07:40,340
+الـ Antibody كثير قليلة ومش كافية أنها تشبك كل ال
+
+123
+00:07:40,340 --> 00:07:43,420
+Antibodies مع بعض زي ما انتوا شايفين هي عندي ال
+
+124
+00:07:43,420 --> 00:07:47,700
+Antibodies بهذا الشكل كميتها قليلة هتلاقي ال
+
+125
+00:07:47,700 --> 00:07:52,880
+Antibody صيرله محاوط بالـ Antigen كمية ال Antigen
+
+126
+00:07:52,880 --> 00:07:55,400
+كتير كبيرة فال Antibody مش قادر يشبك كل ال
+
+127
+00:07:55,400 --> 00:07:57,940
+Antigens مع بعضهذا الـ typical shape لـ
+
+128
+00:07:57,940 --> 00:08:00,760
+precipitation curve وبرضه لـ agglutination curve
+
+129
+00:08:00,760 --> 00:08:04,080
+المنطقة الأولى Antibody exists المنطقة التانية
+
+130
+00:08:04,080 --> 00:08:08,080
+منطقة ال equivalence المنطقة التالتة منطقة الانتجن
+
+131
+00:08:08,080 --> 00:08:15,540
+exist طبعا
+
+132
+00:08:15,540 --> 00:08:20,480
+هنا بقولك نشوف إيش المكتوب ال zone of antibody
+
+133
+00:08:20,480 --> 00:08:23,690
+exists اللي هي bra zoneالـ precipitation is
+
+134
+00:08:23,690 --> 00:08:27,850
+inhibited and antibody not bound to antigen can be
+
+135
+00:08:27,850 --> 00:08:32,050
+detected in the supernatant شو يعني؟ يعني بيبقى
+
+136
+00:08:32,050 --> 00:08:35,890
+كمية ال antibody كتيرة فبالتالي لو أنا جيت عمل
+
+137
+00:08:35,890 --> 00:08:38,730
+centrifuge حلاقي كمية كبيرة من ال antibody
+
+138
+00:08:38,730 --> 00:08:43,850
+separated أو ضلت بدون تفاعل في ال supernatant في
+
+139
+00:08:43,850 --> 00:08:46,250
+ال zone of equivalence الوضع كويس والـ
+
+140
+00:08:46,250 --> 00:08:49,620
+precipitation بيكون عاليولو عملت centrifuge لا
+
+141
+00:08:49,620 --> 00:08:52,400
+بلاقي أنتجن في السوبرناتان زيادة ولا بلاقي
+
+142
+00:08:52,400 --> 00:08:56,160
+antibody ال zone of antigen exist أو bossed zone
+
+143
+00:08:56,160 --> 00:09:00,440
+طبعا هنا ال precipitation is inhibited and antigen
+
+144
+00:09:00,440 --> 00:09:04,200
+not bound to antibody هنا لو جيت عملت centrifuge
+
+145
+00:09:04,200 --> 00:09:07,440
+اللي هيزيد عندي ولا أي مش مرتبط اللي هو الانتجن
+
+146
+00:09:07,440 --> 00:09:16,060
+هلاقي exist من الانتجن في السوبرناتان طيب
+
+147
+00:09:16,350 --> 00:09:20,450
+بريسبيتاشن in liquid من أشكال الـ precipitation in
+
+148
+00:09:20,450 --> 00:09:23,750
+liquid اللي هو البطم البريسبيتات إيش يعني بطم
+
+149
+00:09:23,750 --> 00:09:29,570
+البريسبيتات؟ هتلاحظي إنه البريسبيتات
+
+150
+00:09:29,570 --> 00:09:33,630
+بترسم في قاع الأنبوبة وهذا إحنا حكيناه لما شرحنا
+
+151
+00:09:33,630 --> 00:09:37,030
+الـ Vidal Test لما شرحنا الـ Vidal Test قولنا فيه
+
+152
+00:09:37,030 --> 00:09:41,560
+طريقتين للـ Vidalالطريقة الأولى اللى هى
+
+153
+00:09:41,560 --> 00:09:46,540
+agglutination والطريقة التانية precipitation مظبوط
+
+154
+00:09:46,540 --> 00:09:51,800
+حلقات ال precipitation زى ما حكينا يعنى هو تكلفته
+
+155
+00:09:51,800 --> 00:09:55,860
+عالية فبالتالي مابنعملش كتير لكن حكينا عنهإنه بحط
+
+156
+00:09:55,860 --> 00:09:58,140
+الـ Antibody و الـ Antigen و بتحلهم الظروف إنهم
+
+157
+00:09:58,140 --> 00:10:01,220
+يعملوا precipitation و بعمللهم centrifuge هنا في
+
+158
+00:10:01,220 --> 00:10:05,940
+هذه الحالة هيترسب الـ precipitates في قاع الأنفوبة
+
+159
+00:10:05,940 --> 00:10:09,780
+على شكل راسب أبيض ألاحظوا معنى الكلام إذا كان
+
+160
+00:10:09,780 --> 00:10:13,100
+موجود بيكون positive إذا النوع الأول bottom
+
+161
+00:10:13,100 --> 00:10:18,760
+precipitate النوع التاني اللي هو ring precipitate
+
+162
+00:10:18,760 --> 00:10:24,970
+هنا إيش اللي بيصير؟بكون في عندي two solutions واحد
+
+163
+00:10:24,970 --> 00:10:27,830
+للـ Antibody وواحد للـ Antigen يعني على سبيل
+
+164
+00:10:27,830 --> 00:10:31,550
+المثال الـ Sample و الـ Reagent مثلا الـ Antigen
+
+165
+00:10:31,550 --> 00:10:35,350
+هو الـ Sample و الـ Reagent هو الـ Antibody بحط
+
+166
+00:10:35,350 --> 00:10:39,130
+مثلا الـ Antibody و بعد هيك بحط فوق الـ Antigen
+
+167
+00:10:39,130 --> 00:10:44,630
+هلقيت يشترط عشان يكون التفاعل على شكل رنج أن يكون
+
+168
+00:10:44,630 --> 00:10:48,930
+السائل المذاب فيه المحلولين مختلفين في الكثافة
+
+169
+00:10:48,930 --> 00:10:53,110
+عشان ييجوا فوق بعض وما يختلطوشهيجي السائل اللي فيه
+
+170
+00:10:53,110 --> 00:10:56,590
+الـ Antigen مثلا فأل على فأل و السائل اللي فيه الـ
+
+171
+00:10:56,590 --> 00:11:00,990
+Antibody تحت في منطقة التلامس هتظهر عندي zone of
+
+172
+00:11:00,990 --> 00:11:04,330
+precipitation اللي هي منطقة الـ equivalence هيتكون
+
+173
+00:11:04,330 --> 00:11:08,430
+عندي visible precipitation بهذا الشكل يعني هيبقى
+
+174
+00:11:08,430 --> 00:11:14,850
+في عندي فأل محلول و تحت محلول و هذا التفاعل موجود
+
+175
+00:11:14,850 --> 00:11:19,010
+في الوسط طبعا هنا يا بنات ممكن أعمل ال reaction في
+
+176
+00:11:19,010 --> 00:11:23,440
+تيوب عاديةأو بـ Capillary Tube «رنج بريسبيتات» أو
+
+177
+00:11:23,440 --> 00:11:26,720
+«Ring Test» «A Tube Precipitation Test» «Involve
+
+178
+00:11:26,720 --> 00:11:29,880
+Soluble Antigens with Antibodies in Tube Test or
+
+179
+00:11:29,880 --> 00:11:34,040
+Capillary Tube Layer Antigen of Over Antibody»
+
+180
+00:11:34,040 --> 00:11:37,340
+طبعاً السائق الـ «Reagent» والـ «Sample»
+
+181
+00:11:37,340 --> 00:11:40,760
+«بريسبيتات» occur at the interface of the two
+
+182
+00:11:40,760 --> 00:11:44,440
+reagents forming a ring هيكون عندي حلقة بين التنين
+
+183
+00:11:44,440 --> 00:11:49,020
+يعتبر فحص بسيطلكنه equalitative test يعني ما
+
+184
+00:11:49,020 --> 00:11:52,180
+بيعطيكي نتائج quantitative بيعطيكي بس positive أو
+
+185
+00:11:52,180 --> 00:11:56,680
+negative طيب
+
+186
+00:11:56,680 --> 00:12:00,520
+طريقة قياس ال precipitation ممكن نقيس ال
+
+187
+00:12:00,520 --> 00:12:03,320
+precipitation يا بنات اللي حصل إما عن طريق
+
+188
+00:12:03,320 --> 00:12:07,180
+التربيدومتري أو عن طريق النفلومتري إذا أنا بدي أخد
+
+189
+00:12:07,180 --> 00:12:11,360
+قراءات quantitative لل precipitation في ال liquid
+
+190
+00:12:11,360 --> 00:12:15,220
+باخدها إما على طريق التربيدومتري أو النفلومتري شو
+
+191
+00:12:15,220 --> 00:12:20,150
+بتعتمد هذا الطرق؟الحاجة التربيدومتري التربيدومتري
+
+192
+00:12:20,150 --> 00:12:23,150
+بتعتمد على إنه لما بيصير الـ Antigen Antibody
+
+193
+00:12:23,150 --> 00:12:27,670
+reaction و بتكون البريسبيتات البريسبيتات هذا لو
+
+194
+00:12:27,670 --> 00:12:32,070
+أجهت مررت خلاله ضوء هيعمل scattering للضوء هيعمل
+
+195
+00:12:32,070 --> 00:12:38,350
+تشتت للإضاءة فبالتالي عندي الكيوفت أنا فيها الراسب
+
+196
+00:12:38,350 --> 00:12:43,090
+أو فيها ال reaction اللي اتكون فيه راسب هيعدي
+
+197
+00:12:43,090 --> 00:12:47,180
+عليها الضوء جزء من الضوء هيتشتتوجزء هينفذ للـ
+
+198
+00:12:47,180 --> 00:12:51,020
+«Detector» تمام؟ أنا لو قصت الجزء اللي بينفذ للـ
+
+199
+00:12:51,020 --> 00:12:55,940
+«Detector» تمام، بكون أعرفت أداش من الضوء تشتت
+
+200
+00:12:55,940 --> 00:13:01,120
+أكيد كمية الضوء اللي تشتتت مش اللي انقاست كمية
+
+201
+00:13:01,120 --> 00:13:04,700
+الضوء اللي صارلها scattering تتناسب ترضيا مع تركيز
+
+202
+00:13:04,700 --> 00:13:08,740
+المتفاعلات بينما قراءة الـ «Absorbance» تتناسب
+
+203
+00:13:08,740 --> 00:13:12,820
+عكسيا مع المتفاعلات لأن كل مكان متفاعلات أكتر كل
+
+204
+00:13:12,820 --> 00:13:17,290
+مكان اتشتت أكتركل ما كانت كمية الضوء اللي وصلة للـ
+
+205
+00:13:17,290 --> 00:13:20,690
+Detector أقل إذاً هذه الطريقة اسمها الـ
+
+206
+00:13:20,690 --> 00:13:24,930
+Thermidometry is an analytical technique that uses
+
+207
+00:13:24,930 --> 00:13:29,090
+light scattering a physical phenomena resulting
+
+208
+00:13:29,090 --> 00:13:32,730
+from the interaction of light with particles in
+
+209
+00:13:32,730 --> 00:13:39,460
+solution تمام؟لتقوم بمعاملة مقاطع البرتقالات صورة
+
+210
+00:13:39,460 --> 00:13:43,900
+الـ Photometric Signal تم إجراءها بتدخل في الضوء
+
+211
+00:13:43,900 --> 00:13:49,880
+بقوة كتابة مباشرة لتزيد الـ turbidity يعني كل ما
+
+212
+00:13:49,880 --> 00:13:53,600
+زادت الـ turbidity كل ما قلت الإشارة اللي واصلة
+
+213
+00:13:53,600 --> 00:13:57,520
+للـ detector في الـ reaction well الـ
+
+214
+00:13:57,520 --> 00:14:01,020
+Immunoturbidometry يستخدم الـ classical antigen
+
+215
+00:14:01,020 --> 00:14:03,660
+antibody reaction يعني احنا بداية بنعمل ال
+
+216
+00:14:03,660 --> 00:14:06,870
+reactionالـ Antigen Antibody Complexes كانت
+
+217
+00:14:06,870 --> 00:14:12,110
+بارتيكالات كانت ملاحظة بشكل فوتومتر فهي الطريقة
+
+218
+00:14:12,110 --> 00:14:16,750
+شبيهة بالكالوريمتري العادية اللي احنا بنعرفها لكن
+
+219
+00:14:16,750 --> 00:14:23,330
+هنا لا تعتمد على أن الألوان بتمطس الضوء لأ هنا
+
+220
+00:14:23,330 --> 00:14:27,710
+بتعتمد على أن البرتيكلز بتعمل scattering للضوء
+
+221
+00:14:27,710 --> 00:14:34,770
+وانا بقيص الضوء اللي لم يحدث له scatteringيمكن أن
+
+222
+00:14:34,770 --> 00:14:37,530
+انتوا بتذكروا لما أخدنا الـ Calorimetry قلنا قد
+
+223
+00:14:37,530 --> 00:14:39,990
+تكون Calorimetry أو Terbidometry يعني ممكن أقاس
+
+224
+00:14:39,990 --> 00:14:46,810
+لون أو أقاس تشتت في الإضاءة الطريقة
+
+225
+00:14:46,810 --> 00:14:51,030
+التانية اللي هي طريقة النفلومتري طريقة النفلومتري
+
+226
+00:14:51,030 --> 00:14:55,050
+طبعا هي is a technique used in immunology to
+
+227
+00:14:55,050 --> 00:14:57,770
+determine the levels of several blood sample
+
+228
+00:14:57,770 --> 00:15:02,130
+proteins طريقة بتمن خلالها قياس مجموعة من ال
+
+229
+00:15:02,130 --> 00:15:06,480
+plasma proteinsزي الـ Levels للـ Antibodies زي الـ
+
+230
+00:15:06,480 --> 00:15:13,880
+IgM، IgG، IgA طيب، من التطبيقات المهمة اللي ممكن
+
+231
+00:15:13,880 --> 00:15:17,060
+تشخيصها أو من الأمراض المهمة اللي ممكن قياس
+
+232
+00:15:17,060 --> 00:15:20,580
+بروتيناتها اللي بتطلع فيها من خلال الـ
+
+233
+00:15:20,580 --> 00:15:23,320
+Nephelometry اللي هي الـ Multiple Myeloma طبعاً
+
+234
+00:15:23,320 --> 00:15:25,780
+أنتوا عارفين أن الـ Multiple Myeloma عبارة عن مرض
+
+235
+00:15:25,780 --> 00:15:29,540
+في الـ Plasma Cell بسررها Proliferation إزيادة
+
+236
+00:15:29,930 --> 00:15:33,410
+فبتصير تطلع antibodies الـ antibodies لما بتتكون
+
+237
+00:15:33,410 --> 00:15:36,090
+مابتتكونش كاملة بتتكون ال light chain لحال و ال
+
+238
+00:15:36,090 --> 00:15:39,450
+heavy chain لحال و بعد هيك بيصيرلهم ارتباط فلقيت
+
+239
+00:15:39,450 --> 00:15:43,310
+لما بيكون فيه زيادة و سرعة في التصنيع ممكن مايصيرش
+
+240
+00:15:43,310 --> 00:15:47,010
+الارتباط هذا بالشكل الكافي فحنلاقي زيادة من بعض ال
+
+241
+00:15:47,010 --> 00:15:50,030
+light chain أو ال heavy chain هذه تعتبر para
+
+242
+00:15:50,030 --> 00:15:53,570
+proteins أو بروتينات خاصة بتم قياسها بالطرق
+
+243
+00:15:53,570 --> 00:15:58,740
+المناعيةطبعا quantification is important for
+
+244
+00:15:58,740 --> 00:16:01,460
+disease classification ممكن يلزم فيه تصنيف أو
+
+245
+00:16:01,460 --> 00:16:06,040
+تشخيص المرض كمان لمتابعة المريض اللي بياخد علاج
+
+246
+00:16:06,040 --> 00:16:11,760
+أشهى
+
+247
+00:16:11,760 --> 00:16:15,520
+ال principle بتاعة ال nephelometry ال nephelometry
+
+248
+00:16:15,520 --> 00:16:20,380
+بتشبه ال terpidometry أنه بتعتمد على إنه في عندي
+
+249
+00:16:20,380 --> 00:16:24,440
+particles نتيجة ال antigen antibody reaction تكونت
+
+250
+00:16:24,790 --> 00:16:29,010
+والـ Particles هذه بتعمل Scattering للضوء، تمام؟
+
+251
+00:16:29,010 --> 00:16:32,970
+أول حاجة، نوع الضوء المستخدم مختلف هنا بيستخدموا
+
+252
+00:16:32,970 --> 00:16:39,430
+Laser Beam، تمام؟ Laser Light، بيستخدموا ضوء Laser
+
+253
+00:16:39,430 --> 00:16:43,730
+هناك كنا نستخدم ضوء عادي طول موجه 415 نانومتر بإيس
+
+254
+00:16:43,730 --> 00:16:49,530
+الـ Turbidity، كويس؟ طيب، هناك في الـ Turbidometry
+
+255
+00:16:49,530 --> 00:16:55,380
+كنا نقيس الضوء اللي نفذ ووصل للـ Detectorهنا بنقيص
+
+256
+00:16:55,380 --> 00:16:59,740
+الضوء اللي صارله انعكاس عند زاوية معينة يعني ممكن
+
+257
+00:16:59,740 --> 00:17:03,480
+الضوء يصيره انعكاس عند 30، عند 90، عند 70 وبيصيره
+
+258
+00:17:03,480 --> 00:17:06,940
+انعكاس في أكتر من اتجاه لكن حسب ما أنا أضبط الجهاز
+
+259
+00:17:06,940 --> 00:17:11,760
+ممكن أقيص انعكاس الضوء بمعنى إن هي مثلا الضوء نفذ
+
+260
+00:17:11,760 --> 00:17:17,220
+في هذا المحلول في ضوء بيظل ماشي عدل وفي ضوء هينعكس
+
+261
+00:17:18,090 --> 00:17:21,930
+هيصير تشتت له هلاقيت الضوء اللي انعكس هذا هو اللي
+
+262
+00:17:21,930 --> 00:17:26,150
+بقيسه طبعا هنا هيكون التناسب طردي بين كمية الضوء
+
+263
+00:17:26,150 --> 00:17:32,110
+اللي انعكست وبين القراءة تاعت الـ detector ليش؟
+
+264
+00:17:32,110 --> 00:17:35,410
+لأن كل ما كانت ال molecules أكتر كل ما كانت
+
+265
+00:17:35,410 --> 00:17:42,150
+القراءة أعلىبالنسبة للمصطلح أن محطة صغيرة ستقوم
+
+266
+00:17:42,150 --> 00:17:46,250
+بتحطيم ضوء صغير ستقوم بتحطيم ضوء صغير ستقوم بتحطيم
+
+267
+00:17:46,250 --> 00:17:48,550
+ضوء صغير ستقوم بتحطيم ضوء صغير ستقوم بتحطيم ضوء
+
+268
+00:17:48,550 --> 00:17:49,870
+صغير ستقوم بتحطيم ضوء صغير ستقوم بتحطيم ضوء صغير
+
+269
+00:17:49,870 --> 00:17:54,550
+ستقوم بتحطيم ضوء صغير ستقوم بتحطيم ضوء صغير ستقوم
+
+270
+00:17:54,550 --> 00:17:56,790
+بتحطيم ضوء صغير ستقوم بتحطيم ضوء صغير ستقوم بتحطيم
+
+271
+00:17:56,790 --> 00:18:03,150
+ضوء صغير ستقوم بتحطيم ضوء صغير
+
+272
+00:18:07,360 --> 00:18:11,600
+Antibody and Antigen are mixed in concentrations
+
+273
+00:18:11,600 --> 00:18:15,920
+such that only small aggregates are formed that
+
+274
+00:18:15,920 --> 00:18:18,720
+don't quickly settle to the bottom هذه النقطة كتير
+
+275
+00:18:18,720 --> 00:18:22,940
+مهمة قلقت لما باجي بعمل ال reaction يفترض أنه تكون
+
+276
+00:18:22,940 --> 00:18:26,560
+التركيز قليل لل Antigen وAntibody بعمللهم dilution
+
+277
+00:18:26,560 --> 00:18:31,620
+قبل ما أشتغل عليهم عشان أنا مابدى تتكون عندي large
+
+278
+00:18:31,620 --> 00:18:35,250
+particlesلو اتكونت large particles هتنزل لقاع
+
+279
+00:18:35,250 --> 00:18:39,090
+الأنبوبة ومش هتقدر تعمل scattering للضوء اللي بيمر
+
+280
+00:18:39,090 --> 00:18:43,290
+فبالتالي أنا بدي تتكون فقط small particles عشان ال
+
+281
+00:18:43,290 --> 00:18:47,230
+particles هذه تتظل suspended في المحلول ولمّا يمر
+
+282
+00:18:47,230 --> 00:18:50,430
+الضوء من خلالها تعمله scattering وأقدر أقيص لـ
+
+283
+00:18:50,430 --> 00:18:53,970
+scatter عند زاوية معينة The amount of light
+
+284
+00:18:53,970 --> 00:18:57,050
+scattered is measured and compared to the amount
+
+285
+00:18:57,050 --> 00:19:01,960
+of scatter from non-mixture أكيدزي الـ
+
+286
+00:19:01,960 --> 00:19:05,200
+Thermodermetry و زي الـ Calorimetry لازم يكون في
+
+287
+00:19:05,200 --> 00:19:09,400
+عنده standard ال standard هذا بيكون تركيزه معروف
+
+288
+00:19:09,400 --> 00:19:13,040
+فبقيس درجة ال scattering و بقارنها بال scattering
+
+289
+00:19:13,040 --> 00:19:17,480
+لل standard لل standard و بحسب النتيجة اللي عندى
+
+290
+00:19:17,890 --> 00:19:21,170
+العدد من الاتصالات غير معروفة من خلال طريقة عامة
+
+291
+00:19:21,170 --> 00:19:25,310
+طبعا من خلال هذه الطريقة عامة برسم طريقة عامة
+
+292
+00:19:25,310 --> 00:19:29,410
+وبحسب النتيجة تبعتي يعني الـ scatter قداش، قداش
+
+293
+00:19:29,410 --> 00:19:32,810
+بقابله الـ concentration نفلومتري يمكن استخدامه
+
+294
+00:19:32,810 --> 00:19:36,470
+لتحقق أيضا أنتجين أو أنتيبودي ولكن يتم استخدامه
+
+295
+00:19:36,470 --> 00:19:41,850
+أكثر
+
+296
+00:19:41,850 --> 00:19:46,640
+شيوعاًلتحديد الـ Antigen مش الـ Antibody وإنما
+
+297
+00:19:46,640 --> 00:19:52,920
+بستخدم الـ Antibody كـ Reagent أنواع النفلومتري
+
+298
+00:19:52,920 --> 00:19:57,720
+النفلومتري نوعين نوع بيسموه Endpoint ونوع بيسموه
+
+299
+00:19:57,720 --> 00:20:01,860
+Kinetic إيش الفرق بين ال Endpoint و ال Kinetic ال
+
+300
+00:20:01,860 --> 00:20:06,500
+Endpoint أنا فيه بسمح لكل المتفاعلات إنها تتفاعل
+
+301
+00:20:06,500 --> 00:20:11,180
+بشكل كامل كل ال Analyte اللي أنا بقيسه بدي يتفاعل
+
+302
+00:20:11,540 --> 00:20:15,620
+مايدلش منه ولا حاجة يعني حتى لو ضفت X من الكاشف من
+
+303
+00:20:15,620 --> 00:20:19,400
+المادة اللي بتكشف عنه أو بتتفاعل معاه مش راح يصير
+
+304
+00:20:19,400 --> 00:20:22,500
+تفاعل إضافي ليش؟ لأن كل المادة اللي بدور عليها
+
+305
+00:20:22,500 --> 00:20:26,200
+اتفاعلت هذه بسميها End Point هذه هي بالظبط اللي
+
+306
+00:20:26,200 --> 00:20:29,340
+شغلنا عليها إذا فاكرين لما شغلنا calorie metric
+
+307
+00:20:29,340 --> 00:20:32,860
+لفحص السكر وفحص البروتين كله كنا نشتغله End Point
+
+308
+00:20:32,860 --> 00:20:37,420
+يعني كنا يا بنات نشتغل وأقولكم معاكي نص ساعة تقرأ
+
+309
+00:20:37,420 --> 00:20:40,580
+يعني بعد ال incubation اللي لازم إجراء الفحص مثلا
+
+310
+00:20:40,580 --> 00:20:45,430
+ربع ساعةأقولكم معاك ساعة أو نص ساعة تقرأ الفحص ليش
+
+311
+00:20:45,430 --> 00:20:48,610
+قلتلك ساعة أو نص ساعة يعني اللي هو مش هيزيد لأن كل
+
+312
+00:20:48,610 --> 00:20:53,130
+إش اتفاعل خلصت التفاعل تمام على خلاف الطريقة
+
+313
+00:20:53,130 --> 00:20:56,110
+التانية احنا عادة بنستخدمها للإنزيمات اللي بيسموها
+
+314
+00:20:56,110 --> 00:21:01,890
+كائنة X كائنة X بتعتمد على معدل تغير القراءة كيف
+
+315
+00:21:01,890 --> 00:21:06,550
+يعني؟ بخلي المتفاعلات تبدأ تتفاعل وبسير أخد كل
+
+316
+00:21:06,550 --> 00:21:11,260
+دقيقة قراءةطبعاً معدل الزيادة في القراءة بيدل على
+
+317
+00:21:11,260 --> 00:21:15,680
+تركيز المواد المتفاعلة وفي طريقة معينة بحصل من
+
+318
+00:21:15,680 --> 00:21:19,420
+خلالها بجيب الفرق بين القراءات وبدرم في factor
+
+319
+00:21:19,420 --> 00:21:23,560
+معين هذا ال factor طبعاً بيكون مزودني حسب الفحث
+
+320
+00:21:23,560 --> 00:21:27,000
+اللي أنا بشتغله إذن ال «Kinetic» ما بيصير تفاعل
+
+321
+00:21:27,000 --> 00:21:31,380
+بشكل كامل يعني مش كل ال «Analytes» بتفاعل وإنماأنا
+
+322
+00:21:31,380 --> 00:21:36,880
+بشوف سلوكه بشوف قداش معدل الزيادة في القراءة على
+
+323
+00:21:36,880 --> 00:21:40,420
+فترات زمانية متساوية و بعدين بجيب الفرق بالقراءة
+
+324
+00:21:40,420 --> 00:21:44,620
+أو له طريقة معينة للحساب تمام؟ طيب مين أفضل ال
+
+325
+00:21:44,620 --> 00:21:49,580
+«endpoint» ولا ال «kinetic»؟ خلينا نشوف ال
+
+326
+00:21:49,580 --> 00:21:54,530
+«endpoint» نفلومتري خلينا نشوف إيش مكتوب عنهاهي
+
+327
+00:21:54,530 --> 00:22:03,810
+تعمل بإعطاء الانتجار الانتجار الانتجار
+
+328
+00:22:03,810 --> 00:22:07,350
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+329
+00:22:07,350 --> 00:22:09,870
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+330
+00:22:09,870 --> 00:22:11,430
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+331
+00:22:11,430 --> 00:22:17,290
+الانتجار الانتجار الانتجار الانتجار
+
+332
+00:22:17,290 --> 00:22:17,730
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+333
+00:22:17,730 --> 00:22:21,390
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+334
+00:22:21,390 --> 00:22:27,210
+الانتجهتنزل لقاع الأنبوبة وبالتالي هتأثر على الـ
+
+335
+00:22:27,210 --> 00:22:29,870
+Scattering Reading يعني بدل ما تكون Suspended في
+
+336
+00:22:29,870 --> 00:22:33,610
+المحلول وتكون جزء مهم من الـ Scattering هي هتنزل
+
+337
+00:22:33,610 --> 00:22:36,890
+تحت ومش هتشتغل يعني مش هتعمل Scattering فبالتالي
+
+338
+00:22:36,890 --> 00:22:40,850
+هتأثر عندي على النتيجة بينما الـ Kinetic مش هيصير
+
+339
+00:22:40,850 --> 00:22:43,870
+الكلام هذا فيها لأنه أنا ما بسمح لل Large
+
+340
+00:22:43,870 --> 00:22:48,450
+Aggregates هذه تتكون وإنما بشتغل بسرعة بمجرد ما ال
+
+341
+00:22:48,450 --> 00:22:52,930
+reaction يبدأ و الحبيبات لسه صغيرة بقدر أخد قراءة
+
+342
+00:22:53,660 --> 00:22:57,260
+في قائمة الكنيفلومتري قيمة الـ Scatter هي مقالة
+
+343
+00:22:57,260 --> 00:23:03,600
+بعد إضافة الانتجان، فلو كانت الانتجان مستمر، قيمة
+
+344
+00:23:03,600 --> 00:23:08,880
+التغيير يمكن أن تكون مرتبطة بقيمة الانتجان الموجود
+
+345
+00:23:08,880 --> 00:23:14,300
+في
+
+346
+00:23:14,300 --> 00:23:20,600
+العينة هنا عندي قائمة طويلة جدا بالبروتينات
+
+347
+00:23:21,930 --> 00:23:25,430
+والمُركّبات والأشياء اللي بتعتبر كـantigen في
+
+348
+00:23:25,430 --> 00:23:30,530
+الجسم ممكن إحنا نقيصها باستخدام الـNiflometry في
+
+349
+00:23:30,530 --> 00:23:33,150
+منها الـComplement Components فيها الـProteins
+
+350
+00:23:33,150 --> 00:23:36,310
+فيها الـHaptoglobin فيها Cryoglobulin أشياء كتيرة
+
+351
+00:23:36,310 --> 00:23:42,470
+خالص ممكن نقيصها باستخدام الـNiflometry هنا عندك
+
+352
+00:23:42,470 --> 00:23:45,490
+مقارنة بين الـTerpidometry وNiflometry بشكل عام
+
+353
+00:23:45,490 --> 00:23:49,420
+الـTintin بيصير الـPrecipitation بـSolutionالـ
+
+354
+00:23:49,420 --> 00:23:52,560
+Turbidometry بنقيص الـ Light Extraction يعني الضوء
+
+355
+00:23:52,560 --> 00:23:55,680
+اللي نفذ على 180 درجة اللي ضاله ماشي عدل وطلع
+
+356
+00:23:55,680 --> 00:24:00,160
+بينما هنا بنقيص الضوء اللي صارله Scattering على
+
+357
+00:24:00,160 --> 00:24:05,720
+زاوية معينة طبعا هنا التناسب هيكون عكسي هنا
+
+358
+00:24:05,720 --> 00:24:09,680
+التناسب هيكون طردي الـ Turbidometry عكسي في الـ
+
+359
+00:24:09,680 --> 00:24:13,220
+Nephelometry طردي النتائج في كلا التنان بقرأها من
+
+360
+00:24:13,220 --> 00:24:14,680
+خلال standard curve
+
+361
+00:24:19,570 --> 00:24:25,790
+واش هي مزايا التربيدومتري والنيفلومتري طبعا ممكن
+
+362
+00:24:25,790 --> 00:24:29,190
+من خلالها انقيص الـ Serum protein concentration
+
+363
+00:24:29,190 --> 00:24:32,170
+ممكن انقيص immunoglobulin يعني ممكن انقيص أشياء
+
+364
+00:24:32,170 --> 00:24:37,150
+كتيرة من خلالهم وطرق سريعة وممكن تنعمل full
+
+365
+00:24:37,150 --> 00:24:41,210
+automated بعدين بتلزم يعني ممكن لو كان عندي load
+
+366
+00:24:41,210 --> 00:24:45,590
+كبير في الشغل وعينات كتيرة ممكن تكون طريقة سهلة
+
+367
+00:24:45,590 --> 00:24:47,290
+وكويسة لهيك الشغل
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/dgRcKWVpf5Q_raw.json b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/dgRcKWVpf5Q_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..416e45a6fdc7c3429bb3328975f87ed5d1af58df
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/dgRcKWVpf5Q_raw.json
@@ -0,0 +1 @@
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{"start": 559.87, "end": 560.45, "word": " in", "probability": 0.92333984375}, {"start": 560.45, "end": 560.93, "word": " liquid", "probability": 0.962890625}, {"start": 560.93, "end": 561.19, "word": " اللي", "probability": 0.8330078125}, {"start": 561.19, "end": 561.45, "word": " هو", "probability": 0.98779296875}, {"start": 561.45, "end": 561.95, "word": " البطم", "probability": 0.7322591145833334}, {"start": 561.95, "end": 562.93, "word": " البريسبيتات", "probability": 0.7825113932291666}, {"start": 562.93, "end": 563.21, "word": " إيش", "probability": 0.68896484375}, {"start": 563.21, "end": 563.41, "word": " يعني", "probability": 0.9619140625}, {"start": 563.41, "end": 563.75, "word": " بطم", "probability": 0.8740234375}, {"start": 563.75, "end": 565.33, "word": " البريسبيتات؟", "probability": 0.8943917410714286}, {"start": 565.33, "end": 566.07, "word": " هتلاحظي", "probability": 0.9544270833333334}, {"start": 566.07, "end": 566.51, "word": " إنه", "probability": 0.6455078125}, {"start": 566.51, "end": 569.57, "word": " البريسبيتات", "probability": 0.93994140625}, {"start": 569.57, "end": 570.17, "word": " بترسم", "probability": 0.9449869791666666}, {"start": 570.17, "end": 570.39, "word": " في", "probability": 0.9638671875}, {"start": 570.39, "end": 570.67, "word": " قاع", "probability": 0.869873046875}, {"start": 570.67, "end": 571.37, "word": " الأنبوبة", "probability": 0.95546875}, {"start": 571.37, "end": 571.81, "word": " وهذا", "probability": 0.726806640625}, {"start": 571.81, "end": 572.13, "word": " إحنا", "probability": 0.8347981770833334}, {"start": 572.13, "end": 572.89, "word": " حكيناه", "probability": 0.96943359375}, {"start": 572.89, "end": 573.17, "word": " لما", "probability": 0.9365234375}, {"start": 573.17, "end": 573.63, "word": " شرحنا", "probability": 0.989013671875}, {"start": 573.63, "end": 573.81, "word": " الـ", "probability": 0.541748046875}, {"start": 573.81, "end": 574.09, "word": " Vidal", "probability": 0.75732421875}, {"start": 574.09, "end": 574.43, "word": " Test", "probability": 0.47802734375}, {"start": 574.43, "end": 575.31, "word": " لما", "probability": 0.948974609375}, {"start": 575.31, "end": 575.69, "word": " شرحنا", "probability": 0.9937744140625}, {"start": 575.69, "end": 575.83, "word": " الـ", "probability": 0.8583984375}, {"start": 575.83, "end": 576.11, "word": " Vidal", "probability": 0.931884765625}, {"start": 576.11, "end": 576.37, "word": " Test", "probability": 0.91650390625}, {"start": 576.37, "end": 576.75, "word": " قولنا", "probability": 0.77587890625}, {"start": 576.75, "end": 577.03, "word": " فيه", "probability": 0.76708984375}, {"start": 577.03, "end": 577.77, "word": " طريقتين", "probability": 0.9158935546875}, {"start": 577.77, "end": 578.15, "word": " للـ", "probability": 0.91162109375}, {"start": 578.15, "end": 578.51, "word": " Vidal", "probability": 0.9189453125}], "temperature": 1.0}, {"id": 24, "seek": 59467, "start": 579.3, "end": 594.68, "text": "الطريقة الأولى اللى هى agglutination والطريقة التانية precipitation مظبوط حلقات ال precipitation زى ما حكينا يعنى هو تكلفته عالية فبالتالي مابنعملش كتير لكن حكينا عنه", "tokens": [6027, 9566, 16572, 28671, 16247, 12610, 7578, 13672, 7578, 8032, 7578, 623, 7191, 325, 2486, 16070, 9566, 16572, 28671, 16712, 7649, 10632, 37662, 3714, 19913, 3555, 2407, 9566, 11331, 1211, 4587, 9307, 2423, 37662, 30767, 7578, 19446, 11331, 4117, 1829, 8315, 37495, 1863, 7578, 31439, 6055, 28820, 5172, 47395, 6225, 6027, 10632, 6156, 3555, 6027, 2655, 6027, 1829, 3714, 16758, 1863, 25957, 1211, 8592, 9122, 2655, 13546, 44381, 11331, 4117, 1829, 8315, 18871, 3224], "avg_logprob": -0.1066666692495346, "compression_ratio": 1.6604938271604939, "no_speech_prob": 2.980232238769531e-07, "words": [{"start": 579.3, "end": 579.86, "word": "الطريقة", "probability": 0.9686279296875}, {"start": 579.86, "end": 580.66, "word": " الأولى", "probability": 0.9884440104166666}, {"start": 580.66, "end": 581.04, "word": " اللى", "probability": 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diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/gtCT-93SW7g_raw.json b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/gtCT-93SW7g_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..7963217f1db2fd5a51413929f899bfb3cd3603d6
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/gtCT-93SW7g_raw.json
@@ -0,0 +1 @@
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evaluation يشوف وين صار إحمرار ومن خلال المكان اللي صار فيه إحمرار بنعرف إيش المادة اللي سببت الحساسية عنده", "tokens": [19528, 41891, 11174, 8608, 995, 27884, 16490, 1211, 6027, 23758, 2423, 30543, 2655, 37495, 22653, 9673, 5172, 32887, 11242, 19446, 6055, 19528, 3794, 8592, 9673, 1829, 11703, 3224, 19446, 1829, 3555, 8848, 1211, 8592, 3714, 7435, 3224, 23328, 9122, 3555, 13546, 4724, 5016, 1829, 12984, 14739, 3224, 7251, 2655, 3615, 2288, 11703, 4587, 5296, 33456, 18863, 2288, 4587, 3714, 43020, 7251, 33604, 16254, 30731, 14739, 11296, 6055, 1863, 5172, 4117, 9154, 23758, 9673, 41361, 4032, 1863, 5172, 28543, 27188, 5016, 9381, 34051, 8717, 5016, 36520, 15844, 8717, 31371, 7435, 3660, 46740, 39182, 8032, 4117, 39894, 1863, 8592, 6027, 39182, 19446, 6055, 1863, 8592, 6027, 4724, 13546, 2407, 5016, 24976, 3215, 4117, 2655, 13063, 6225, 8592, 7649, 7251, 25957, 1211, 13344, 7251, 8592, 38688, 4032, 9957, 20328, 9640, 11933, 5016, 29973, 9640, 4032, 27842, 16490, 1211, 6027, 9673, 41361, 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"word": " يؤدي", "probability": 0.7794596354166666}, {"start": 633.38, "end": 633.66, "word": " إلى", "probability": 0.908203125}, {"start": 633.66, "end": 634.1, "word": " أنها", "probability": 0.78125}, {"start": 634.1, "end": 634.64, "word": " تنفك", "probability": 0.8963623046875}, {"start": 634.64, "end": 635.0, "word": " من", "probability": 0.98681640625}, {"start": 635.0, "end": 635.22, "word": " هذا", "probability": 0.92724609375}, {"start": 635.22, "end": 635.72, "word": " المكان", "probability": 0.993896484375}, {"start": 635.72, "end": 636.26, "word": " ونفقد", "probability": 0.9251708984375}, {"start": 636.26, "end": 636.9, "word": " الفحص", "probability": 0.9384765625}, {"start": 636.9, "end": 637.06, "word": " أو", "probability": 0.9140625}, {"start": 637.06, "end": 637.72, "word": " نحصل", "probability": 0.84814453125}, {"start": 637.72, "end": 637.84, "word": " على", "probability": 0.85546875}, {"start": 637.84, "end": 638.22, "word": " نتيجة", "probability": 0.9913330078125}, {"start": 638.22, "end": 638.46, "word": " له", "probability": 0.7841796875}, {"start": 638.46, "end": 639.8, "word": " بعد", "probability": 0.85107421875}, {"start": 639.8, "end": 640.24, "word": " هك", "probability": 0.589599609375}, {"start": 640.24, "end": 641.22, "word": " بتنشال", "probability": 0.833251953125}, {"start": 641.22, "end": 641.6, "word": " بعد", "probability": 0.513671875}, {"start": 641.6, "end": 641.74, "word": " ما", "probability": 0.8671875}, {"start": 641.74, "end": 642.26, "word": " تنشال", "probability": 0.9700927734375}, {"start": 642.26, "end": 642.52, "word": " بيروح", "probability": 0.9298095703125}, {"start": 642.52, "end": 643.02, "word": " للدكتور", "probability": 0.97353515625}, {"start": 643.02, "end": 643.34, "word": " عشان", "probability": 0.9715169270833334}, {"start": 643.34, "end": 643.66, "word": " يعمل", "probability": 0.98681640625}, {"start": 643.66, "end": 644.12, "word": " evaluation", "probability": 0.95751953125}, {"start": 644.12, "end": 644.64, "word": " يشوف", "probability": 0.9607747395833334}, {"start": 644.64, "end": 644.86, "word": " وين", "probability": 0.8466796875}, {"start": 644.86, "end": 645.14, "word": " صار", "probability": 0.980224609375}, {"start": 645.14, "end": 645.7, "word": " إحمرار", "probability": 0.80291748046875}, {"start": 645.7, "end": 646.54, "word": " ومن", "probability": 0.90234375}, {"start": 646.54, "end": 646.88, "word": " خلال", "probability": 0.9967447916666666}, {"start": 646.88, "end": 647.26, "word": " المكان", "probability": 0.991455078125}, {"start": 647.26, "end": 647.44, "word": " اللي", "probability": 0.92822265625}, {"start": 647.44, "end": 647.68, "word": " صار", "probability": 0.986083984375}, {"start": 647.68, "end": 647.88, "word": " فيه", "probability": 0.958984375}, {"start": 647.88, "end": 648.3, "word": " إحمرار", "probability": 0.9710693359375}, {"start": 648.3, "end": 648.68, "word": " بنعرف", "probability": 0.9547526041666666}, {"start": 648.68, "end": 648.94, "word": " إيش", "probability": 0.8330078125}, {"start": 648.94, "end": 649.52, "word": " المادة", "probability": 0.9812825520833334}, {"start": 649.52, "end": 650.04, "word": " اللي", "probability": 0.964111328125}, {"start": 650.04, "end": 650.68, "word": " سببت", "probability": 0.9852294921875}, {"start": 650.68, "end": 652.58, "word": " الحساسية", "probability": 0.9542236328125}, {"start": 652.58, "end": 652.96, "word": " عنده", "probability": 0.989013671875}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 655.661875, "duration_after_vad": 647.5350000000008}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/gtCT-93SW7g_raw.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/gtCT-93SW7g_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..bef57d6faf7dc64320579c3473e63d3bce06497b
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/gtCT-93SW7g_raw.srt
@@ -0,0 +1,640 @@
+1
+00:00:00,910 --> 00:00:04,830
+باسم الله الرحمن الرحيم موضوعنا هيكون ان شاء الله
+
+2
+00:00:04,830 --> 00:00:08,950
+عن diagnosis of cell-mediated immune response
+
+3
+00:00:08,950 --> 00:00:12,490
+diagnosis
+
+4
+00:00:12,490 --> 00:00:17,030
+of cell-mediated response ممكن ينعمل بإحدى طريقتين
+
+5
+00:00:17,030 --> 00:00:21,590
+delayed hypersensitivity reaction أو lymphocyte
+
+6
+00:00:21,590 --> 00:00:25,190
+transformation test delayed hypersensitivity
+
+7
+00:00:25,190 --> 00:00:31,590
+reaction ممكن نعمله عن طريق scratch skintest أو
+
+8
+00:00:31,590 --> 00:00:36,050
+intradermal skin test أو batch test lymphocyte
+
+9
+00:00:36,050 --> 00:00:39,550
+transformation test lymphocyte activation test
+
+10
+00:00:39,550 --> 00:00:43,530
+يعني بنعمل activation للـ lymphocyte وبنشوف ال
+
+11
+00:00:43,530 --> 00:00:47,270
+markers اللي اتكونت على ال lymphocyte عن طريق
+
+12
+00:00:47,270 --> 00:00:52,270
+delayed hypersensitivity skin test هنا هذا الفحص
+
+13
+00:00:52,270 --> 00:00:56,530
+احنا يعني بنعمله عشان نشوف إذا كان الإنسان عنده
+
+14
+00:00:56,530 --> 00:01:01,090
+حساسية لبعض المركباتوإيش هو المركّب اللي بالظبط
+
+15
+00:01:01,090 --> 00:01:05,490
+بتحسس منه طبعا إحنا عارفين إنه ال .. في عندنا
+
+16
+00:01:05,490 --> 00:01:08,490
+immediate .. immediate hypersensitivity reaction
+
+17
+00:01:08,490 --> 00:01:11,850
+وفي عندى delayed hypersensitivity reaction ال
+
+18
+00:01:11,850 --> 00:01:15,090
+immediate بيحصل لما تكون ال circulating antibodies
+
+19
+00:01:15,090 --> 00:01:19,410
+موجودة وجاهزة في ال circulation فبمجرد ما بيدخل
+
+20
+00:01:19,410 --> 00:01:23,290
+الانتجن بيصير ال reaction بينما ال delayed بحتاج ل
+
+21
+00:01:23,290 --> 00:01:27,190
+T cell activationهلقيت الـ T cell activation بحتاج
+
+22
+00:01:27,190 --> 00:01:31,770
+وقت يعني ممكن يحتاج أيام لغاية ما يتكون عشان هيك
+
+23
+00:01:31,770 --> 00:01:37,110
+بسميه delayed hypersensitivity reaction skin
+
+24
+00:01:37,110 --> 00:01:41,330
+testing يعني الآن احنا كل الفحوصات هذه اللي بدنا
+
+25
+00:01:41,330 --> 00:01:48,350
+نحكي عنها يعني خلينا نحكيها بأسلوب بسيط لو في شخص
+
+26
+00:01:48,350 --> 00:01:52,670
+بيعاني من حساسية معينة يعني في ناس بتعاني انه فجأة
+
+27
+00:01:52,670 --> 00:01:56,660
+بيصير عندها حساسيةبس هي مش عارفة إيش العامل أو إيش
+
+28
+00:01:56,660 --> 00:02:01,220
+السبب اللي قدّى لظهور هذه الحساسية عندها طيب كيف
+
+29
+00:02:01,220 --> 00:02:06,260
+بدهم يعرفوا؟ الآن في طرق أنه إحنا نعرض ال skin
+
+30
+00:02:06,260 --> 00:02:10,120
+يعني ندخل تحت ال skin أنواع مختلفة من ال allergen
+
+31
+00:02:10,120 --> 00:02:14,880
+من الأشياء اللي بتسبب حساسية ونشوف مين فيهم اللي
+
+32
+00:02:14,880 --> 00:02:18,220
+عمل ال reaction فبالتالي إحنا بنعرف إيش المسبب
+
+33
+00:02:18,220 --> 00:02:22,580
+للحساسية عند هذا المريض في عنديغالباً هي skin
+
+34
+00:02:22,580 --> 00:02:26,900
+testing يعني فحصات بتنعمل على الجلد بس في أكثر من
+
+35
+00:02:26,900 --> 00:02:31,720
+طريقة لها skin testing is usually done at doctor's
+
+36
+00:02:31,720 --> 00:02:35,200
+office يعني بتنعمل عند الدكتور عند الطبيب and
+
+37
+00:02:35,200 --> 00:02:37,840
+nurse generally administer the test and the doctor
+
+38
+00:02:37,840 --> 00:02:42,180
+interpret the results يعني الممرضة هي اللي بتعمل
+
+39
+00:02:42,180 --> 00:02:46,740
+الفحص والدكتور بيقرأ النتائج هذا الفحص بياخد من 20
+
+40
+00:02:46,740 --> 00:02:54,090
+إلى 40 دقيقة في عندي بعضالأسباب الـ allergen يعني
+
+41
+00:02:54,090 --> 00:02:57,990
+الأشياء المسببة للحساسية نتيجتها بتطلع بسرعة
+
+42
+00:02:57,990 --> 00:03:02,370
+فبتكون هذه عاملة immediate allergic reaction وفي
+
+43
+00:03:02,370 --> 00:03:05,710
+عندي أشياء بتحتاج several days عشان تبين نتيجتها
+
+44
+00:03:05,710 --> 00:03:09,290
+بتكون عاملة delayed allergic reaction نيجي لل skin
+
+45
+00:03:09,290 --> 00:03:12,810
+break testهذا إيه له اسم تاني اللي هو Puncture or
+
+46
+00:03:12,810 --> 00:03:17,870
+Scratch Test هذا بنفحص من خلاله الـ Immediate
+
+47
+00:03:17,870 --> 00:03:20,890
+Allergic Reaction ممكن من خلاله أفحص أربعين
+
+48
+00:03:20,890 --> 00:03:24,450
+Substance يعني أربعين Allergen ممكن يسببوا حساسية
+
+49
+00:03:24,450 --> 00:03:29,050
+ممكن أفحصهم لهذا الشخص عادة من الأشياء اللي ممكن
+
+50
+00:03:29,050 --> 00:03:32,310
+نختبرها إذا كان الإنسان حاسس إلها ولا لأ من خلال
+
+51
+00:03:32,310 --> 00:03:36,130
+هذا الفحص الـPollen اللي هو اللقاح الأنواع من
+
+52
+00:03:36,130 --> 00:03:39,410
+العفن، الـMold، الـPit Under، القطط والحيوانات
+
+53
+00:03:39,410 --> 00:03:43,970
+الأليفةالغبار، بعض الأطعمة ممكن نختبرها عن طريق
+
+54
+00:03:43,970 --> 00:03:48,750
+هذا بيكون عندي مستخلص من هذه الأشياء و بنحطه على
+
+55
+00:03:48,750 --> 00:03:53,530
+الجلد و بنشوف هل صار تهيج ولا ماصارش in adult
+
+56
+00:03:53,530 --> 00:03:56,590
+الفحص هذا بنعمل على ال forearm بينما في ال
+
+57
+00:03:56,590 --> 00:04:01,330
+children بنعمل على ال upper back allergy skin test
+
+58
+00:04:01,330 --> 00:04:04,910
+يعني هنا بقولك أن هذا الفحص مش مؤلم بس مجرد لانست
+
+59
+00:04:04,910 --> 00:04:08,110
+يعني ناخذت لانست لا بنزل دم ولا حاجة يعني ما بخوف
+
+60
+00:04:08,110 --> 00:04:12,930
+بس مجرد لانستلحظة بسيطة هيك بشعر الإنسان بالانزعاج
+
+61
+00:04:12,930 --> 00:04:17,050
+بعد هيك بيروح القلم الآن بعد ما الممرض اتعقم الجلد
+
+62
+00:04:17,050 --> 00:04:21,530
+في المكان اللي بدها تعمل فيه الفحص بكحول بترسم
+
+63
+00:04:21,530 --> 00:04:27,290
+دوائر صغيرة دوائر هادئ يعني بعدد ال allergen اللي
+
+64
+00:04:27,290 --> 00:04:31,310
+هي بدها تستخدمها بعد هيك بتيجي على الدائرة اللي
+
+65
+00:04:31,310 --> 00:04:36,090
+رسمتها بتحط drop من ال allergen المستخلص اللي بدها
+
+66
+00:04:36,090 --> 00:04:40,950
+تشوفهبعد ما تحطها بتيجي من خلال الـ Lancet بتعمل
+
+67
+00:04:40,950 --> 00:04:48,610
+ال puncture يعني بحيث أنه ال Lancet الضربة تيجي في
+
+68
+00:04:48,610 --> 00:04:52,270
+وسط ال drop اللي حطتها كيف هي هيك راح تاخد ال
+
+69
+00:04:52,270 --> 00:04:55,890
+allergen و تدخله لتحت الجلد يعني بتيجي الضربة من
+
+70
+00:04:55,890 --> 00:04:59,430
+خلال ال allergen بحيث أنه لما تعمل ال puncture
+
+71
+00:04:59,430 --> 00:05:03,720
+يفوت هذا ال allergen لتحت الجلد منه جزءونختبر إذا
+
+72
+00:05:03,720 --> 00:05:08,880
+كان في حساسية ولا لأ تستنى 15 دقيقة بعد هيك بتشوف
+
+73
+00:05:08,880 --> 00:05:12,400
+علامات الـ allergy إذا كان فيه صار تحسس كيف بيصير
+
+74
+00:05:12,400 --> 00:05:17,060
+بتصير حبة صغيرة زي أرزة البعوضة يابسة مرتفعة
+
+75
+00:05:17,060 --> 00:05:22,120
+ولونها أحمر فبتكتب الملاحظة وبتأيس القطر بتاع
+
+76
+00:05:22,120 --> 00:05:25,440
+الحبة هذه عشان تعطي المعلومات للدكتور after the
+
+77
+00:05:25,440 --> 00:05:27,740
+nurse records the results he or she will clean
+
+78
+00:05:27,740 --> 00:05:30,840
+your skin with alcohol to remove the mark بعد هيك
+
+79
+00:05:30,840 --> 00:05:35,170
+بتنظف المكان بكحولعشان اتشيل العلامات اللى حطتها
+
+80
+00:05:35,170 --> 00:05:39,090
+للفحص تمام readiness and swelling from positive
+
+81
+00:05:39,090 --> 00:05:42,410
+reaction to allergen فى هنا بعض الحبيبات ظاهرة
+
+82
+00:05:42,410 --> 00:05:48,570
+دليل على انه فى تحسس من بعض المواد اللى أضافتها
+
+83
+00:05:48,570 --> 00:05:53,270
+الممرضة الآن
+
+84
+00:05:53,270 --> 00:05:57,450
+ال quality control لهذا الفحص مهم ان اعمل control
+
+85
+00:05:57,450 --> 00:06:03,470
+باستخدام مادتين هلقيتالنتيجة الـ Positive كانت على
+
+86
+00:06:03,470 --> 00:06:07,550
+شكل إحمرار وتورم في المكان اللي أدخلنا فيه الـ
+
+87
+00:06:07,550 --> 00:06:11,970
+Allergen طيب، إيش سبب التورم والإحمرار هذا؟ مادة
+
+88
+00:06:11,970 --> 00:06:14,910
+الـ Histamine اللي بتطلع، مادة الـ Histamine هذه
+
+89
+00:06:14,910 --> 00:06:20,250
+هي اللي بتسبب الأعراض بتاعت الحساسية طيب، هلاقيت
+
+90
+00:06:20,250 --> 00:06:27,580
+في مشكلة إن في بعض الناس مادة الـ Histamineيعني
+
+91
+00:06:27,580 --> 00:06:30,500
+مابتعملش عندهم reaction يعني ما بتأثر وجود مادة
+
+92
+00:06:30,500 --> 00:06:32,860
+الهستامين لو موجد الهستامين مش هيعمل عندهم
+
+93
+00:06:32,860 --> 00:06:37,080
+reaction visible فبالتالي في هذه الحالة أنا مش راح
+
+94
+00:06:37,080 --> 00:06:40,360
+أعرف أن هذا الشخص تحسس لأنه حتى لو ظهر الهستامين
+
+95
+00:06:40,360 --> 00:06:44,320
+وعمل ال reaction مش هيظهر عندهم نتيجة فعشان هيك
+
+96
+00:06:44,320 --> 00:06:48,860
+لازم أحط drop أدخل فيها هستامين ليش؟ لأن in most
+
+97
+00:06:48,860 --> 00:06:51,560
+people this substance cause a skin response عند
+
+98
+00:06:51,560 --> 00:06:54,770
+معظم الناس if you don't react to histamineyour
+
+99
+00:06:54,770 --> 00:06:57,750
+allergy skin test may not reveal an allergy even
+
+100
+00:06:57,750 --> 00:07:01,290
+if you have one يعني حتى لو انت .. إذا الجلد عندك
+
+101
+00:07:01,290 --> 00:07:05,010
+مش حساس للهستامين حتى لو عندك حساسية مش هتظهر عندك
+
+102
+00:07:05,010 --> 00:07:10,050
+أعرض فبالتالي لما أنا بحط الهستامين المفروض يعطيك
+
+103
+00:07:10,050 --> 00:07:13,730
+احمرار و tenderness هذا ال control ال positive
+
+104
+00:07:13,730 --> 00:07:17,570
+تمام؟ إذا control ال positive هستامين عشان الفحص
+
+105
+00:07:17,570 --> 00:07:21,830
+يكون كويس أو يعني يكون نتائجه دقيقة نيجي لل
+
+106
+00:07:21,830 --> 00:07:24,880
+control التاني اللي هو ال glycerin أو ال salineهذا
+
+107
+00:07:24,880 --> 00:07:27,600
+المفروض لـ Glycerin أو الـ Saline يكون عند كل
+
+108
+00:07:27,600 --> 00:07:31,260
+الناس Negative لأن الـ Extracts عادة الـ Allergen
+
+109
+00:07:31,260 --> 00:07:34,700
+هيكون Suspended إما في Glycerin أو Saline وعادة
+
+110
+00:07:34,700 --> 00:07:37,480
+الناس ما بيكون عندها حساسية لـ Glycerin أو Saline
+
+111
+00:07:37,480 --> 00:07:41,480
+لكن بعض الناس قد يكون عندها تحسس منهمفبالتالي
+
+112
+00:07:41,480 --> 00:07:45,680
+هيعطيني false positive في هذه الحالة عشان هيك هذا
+
+113
+00:07:45,680 --> 00:07:48,980
+ال glycerin أو ال saline لما أدخله تحت الجلد
+
+114
+00:07:48,980 --> 00:07:52,560
+المفروض يكون negative إذا ال control بالهستامين هو
+
+115
+00:07:52,560 --> 00:07:55,440
+اللي لازم يعطيني positive وال glycerin أو saline
+
+116
+00:07:55,440 --> 00:07:58,800
+هو اللي لازم يعطيني negative عشان أقول إن نتيجة
+
+117
+00:07:58,800 --> 00:08:00,360
+الفحص بتاعتي صحيح ال second point التاني اللي هو
+
+118
+00:08:00,360 --> 00:08:04,940
+ال skin injection test هذا بتم عن طريق إدخال كمية
+
+119
+00:08:04,940 --> 00:08:09,180
+من ال allergen عن طريق needle تحت الجلد you may
+
+120
+00:08:09,180 --> 00:08:13,110
+need a testthat use a needle to inject a small
+
+121
+00:08:13,110 --> 00:08:16,330
+amount of allergen extract just into the skin on
+
+122
+00:08:16,330 --> 00:08:19,810
+your arm Intradermal test يعني بتدخله تحت الجلد
+
+123
+00:08:19,810 --> 00:08:23,310
+The injection site is examined after about 15
+
+124
+00:08:23,310 --> 00:08:27,530
+minutes for signs of an allergic reaction your
+
+125
+00:08:27,530 --> 00:08:31,470
+doctor may recommend this test to check for an
+
+126
+00:08:31,470 --> 00:08:34,710
+allergy to insect venom or penicillin يعني من
+
+127
+00:08:34,710 --> 00:08:38,470
+الأشياء اللي ممكن نختبرها بهذا الطريقةالادغات
+
+128
+00:08:38,470 --> 00:08:41,430
+الحشرات و الـ «Batch Test» في عندى طريقة تانية
+
+129
+00:08:41,430 --> 00:08:47,290
+اللى بيختبر فيها الأشياء اللى بتعمل حساسية بالجلد
+
+130
+00:08:47,290 --> 00:08:51,170
+عن طريق التلامس بيسموها Contact Dermatitis زى مثلا
+
+131
+00:08:51,170 --> 00:08:55,790
+مستحضرات التجميل زى بعض الchemicals زى بعض
+
+132
+00:08:55,790 --> 00:08:59,150
+المنظفات اللى مجرد ما تلامس الجلد بيصير فيه حساسية
+
+133
+00:08:59,150 --> 00:09:04,740
+ممكن أختبرها بهذه الطريقة هناباعتمد هذا الفحص على
+
+134
+00:09:04,740 --> 00:09:07,860
+إيش خلّيني أول إش نشوف batch testing is generally
+
+135
+00:09:07,860 --> 00:09:11,620
+done to see whether a particular substance is
+
+136
+00:09:11,620 --> 00:09:14,600
+causing allergic skin irritation دي هم نسميه
+
+137
+00:09:14,600 --> 00:09:19,220
+contact dermatitis batch tests can detect delayed
+
+138
+00:09:19,220 --> 00:09:22,960
+allergic reaction which can take several days to
+
+139
+00:09:22,960 --> 00:09:26,700
+develop يعني ممكن خلال أيام أشوف النتيجة batch
+
+140
+00:09:26,700 --> 00:09:31,680
+tests don't use needle لا needle ولا Lancetلكن إيش
+
+141
+00:09:31,680 --> 00:09:36,680
+بنعمل الـ Allergens هذه بتكون جاهزة بتكون جاهزة
+
+142
+00:09:36,680 --> 00:09:41,320
+بتنجب محطوطة على patch على كيف يعني زي لزقة بيبقى
+
+143
+00:09:41,320 --> 00:09:45,400
+عليها كل أنواع الـ Allergen بنلزقها على الظهر من
+
+144
+00:09:45,400 --> 00:09:49,600
+ورا على ال back و بنشوف إيش اللي بعد فترة معينة
+
+145
+00:09:49,600 --> 00:09:52,480
+بنرفعها و بنشوف إيش الأماكن اللي ظهر فيها إحمرار
+
+146
+00:09:52,480 --> 00:09:56,100
+patch test don't use needle instead allergens are
+
+147
+00:09:56,100 --> 00:09:59,960
+applied to patcheswhich are then placed on your
+
+148
+00:09:59,960 --> 00:10:03,160
+skin during a batch test your skin may be exposed
+
+149
+00:10:03,160 --> 00:10:07,580
+to 20 or 30 extracts of substance that cause
+
+150
+00:10:07,580 --> 00:10:10,740
+contact dermatitis زي الـ latex, medication,
+
+151
+00:10:10,920 --> 00:10:13,800
+fragments, preservatives, hair dye, metals and
+
+152
+00:10:13,800 --> 00:10:19,380
+resin الأشياء اللي حكينا عنها زي ما أنتوا شايفين
+
+153
+00:10:19,380 --> 00:10:23,140
+المريض بيرتدي ال batch بيحطها على ظهره في هذه
+
+154
+00:10:23,140 --> 00:10:28,200
+الأماكنلمدة 48 ساعة خلال هذا الوقت يعني المفروض ما
+
+155
+00:10:28,200 --> 00:10:32,000
+تلمسش الميّه مايبذلش مجهود كبير بحيث أنه يتعرّق
+
+156
+00:10:32,000 --> 00:10:35,720
+لأن العرق ممكن يؤدي إلى أنها تنفك من هذا المكان
+
+157
+00:10:35,720 --> 00:10:41,600
+ونفقد الفحص أو نحصل على نتيجة له بعد هك بتنشال بعد
+
+158
+00:10:41,600 --> 00:10:44,640
+ما تنشال بيروح للدكتور عشان يعمل evaluation يشوف
+
+159
+00:10:44,640 --> 00:10:48,300
+وين صار إحمرار ومن خلال المكان اللي صار فيه إحمرار
+
+160
+00:10:48,300 --> 00:10:52,960
+بنعرف إيش المادة اللي سببت الحساسية عنده
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/peSzn1o5k78_raw.json b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/peSzn1o5k78_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..318edc118aca1eb9464294962b4bb96c746e1c66
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/peSzn1o5k78_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 2569, "start": 2.09, "end": 25.69, "text": "بسم الله الرحمن الرحيم راح نتحدث اليوم إن شاء الله رب العالمين في موضوع بسيط وتطبيقه كتير سهل والكل فينا تقريبا شافه أو بيشوفه اللي هو ال reaction اللي بتم باستخدام strip هذا بسميه immuno أو بعتمد على ال principle اللي هي immunochromatography", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 12602, 39319, 8717, 2655, 24401, 12984, 45595, 20498, 36145, 13412, 16606, 21984, 12602, 3555, 18863, 45340, 9957, 8978, 3714, 2407, 11242, 45367, 4724, 3794, 1829, 9566, 34683, 9566, 21292, 4587, 3224, 9122, 2655, 13546, 8608, 3224, 1211, 4032, 6027, 28820, 8978, 8315, 6055, 4587, 16572, 3555, 995, 13412, 31845, 3224, 34051, 4724, 1829, 8592, 38688, 3224, 13672, 1829, 31439, 2423, 5480, 13672, 1829, 4724, 39237, 4724, 995, 14851, 9778, 3215, 10943, 12828, 23758, 4724, 38251, 1829, 3224, 13154, 78, 34051, 4724, 34268, 2304, 3215, 15844, 2423, 8665, 13672, 1829, 39896, 13154, 8997, 4397, 267, 5820], 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"word": " الـ", "probability": 0.842529296875}, {"start": 289.35, "end": 289.73, "word": " Sample", "probability": 0.62255859375}, {"start": 289.73, "end": 290.33, "word": " وفي", "probability": 0.853759765625}, {"start": 290.33, "end": 290.81, "word": " مكان", "probability": 0.956298828125}, {"start": 290.81, "end": 291.29, "word": " بيصير", "probability": 0.906494140625}, {"start": 291.29, "end": 291.59, "word": " فيه", "probability": 0.991943359375}, {"start": 291.59, "end": 292.47, "word": " التفاعل،", "probability": 0.8140625}, {"start": 292.47, "end": 292.91, "word": " تفاعل", "probability": 0.87939453125}, {"start": 292.91, "end": 293.13, "word": " الـ", "probability": 0.904541015625}, {"start": 293.13, "end": 293.49, "word": " Sample", "probability": 0.85546875}, {"start": 293.49, "end": 294.03, "word": " مع", "probability": 0.9853515625}, {"start": 294.03, "end": 294.25, "word": " الـ", "probability": 0.963134765625}, {"start": 294.25, "end": 294.69, "word": " Detector", 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303.69, "end": 303.93, "word": " Sample", "probability": 0.88330078125}, {"start": 303.93, "end": 304.33, "word": " Bad", "probability": 0.68115234375}, {"start": 304.33, "end": 305.03, "word": " بعد", "probability": 0.5498046875}, {"start": 305.03, "end": 305.49, "word": " هيك،", "probability": 0.8359375}, {"start": 305.49, "end": 305.85, "word": " هيكون", "probability": 0.872802734375}, {"start": 305.85, "end": 306.01, "word": " في", "probability": 0.98193359375}, {"start": 306.01, "end": 306.35, "word": " عندي", "probability": 0.83349609375}, {"start": 306.35, "end": 306.71, "word": " Ash", "probability": 0.6298828125}, {"start": 306.71, "end": 308.53, "word": " Antibody،", "probability": 0.8275146484375}, {"start": 308.53, "end": 308.81, "word": " الـ", "probability": 0.972412109375}, {"start": 308.81, "end": 309.19, "word": " Antibody", "probability": 0.9788411458333334}, {"start": 309.19, "end": 309.69, "word": " هذا", "probability": 0.86865234375}, {"start": 309.69, "end": 310.85, "word": " labelled", "probability": 0.69775390625}, {"start": 310.85, "end": 312.09, "word": " Bicolloidal", "probability": 0.63671875}, {"start": 312.09, "end": 312.51, "word": " Gold", "probability": 0.7939453125}], "temperature": 1.0}, {"id": 12, "seek": 34172, "start": 313.22, "end": 341.72, "text": "شايفين؟ هذا الـ Antibody labelled بكلية دا الـ Gold موجود على الـ «سلاي» على الـ «ستريب» في هذا المكان حلقات لما أنا بحط الـ «سامبل» هتبدأش الـ «سامبل» تمشي بهذا الاتجاه هتقابل الـ Antibody إذا كان الـ Antigen موجود هيصير ارتباط للـ Antigen بالـ Antibody تمام؟ هيصير ارتباط للـ Antigen بالـ Antibody و تظل ماشية إيش أول حاجة هتقابلها؟", "tokens": [8592, 995, 33911, 9957, 22807, 23758, 2423, 39184, 5130, 897, 843, 2715, 41307, 4724, 28820, 10632, 11778, 995, 2423, 39184, 6731, 3714, 29245, 23328, 15844, 2423, 39184, 4657, 3794, 15040, 1829, 5933, 15844, 2423, 39184, 4657, 14851, 16572, 3555, 5933, 8978, 23758, 9673, 41361, 11331, 1211, 4587, 9307, 5296, 15042, 41850, 4724, 5016, 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immunocomplexes with the immobilized antibody resulting in generating a color red purple line حيطلع عندي لون في هذا المكان هذا طبعا اللي سمناه test line طيب الآن بقولك appearance of red purple line", "tokens": [41185, 9154, 9566, 28671, 2423, 39184, 1500, 1622, 6263, 538, 15745, 364, 13154, 905, 298, 18945, 279, 365, 264, 3397, 21725, 1602, 34507, 16505, 294, 17746, 257, 2017, 2182, 9656, 1622, 11331, 1829, 9566, 1211, 3615, 18871, 16254, 5296, 11536, 8978, 23758, 9673, 41361, 23758, 23032, 3555, 3615, 995, 13672, 1829, 8608, 2304, 8315, 3224, 1500, 1622, 23032, 1829, 3555, 6024, 48506, 4724, 39648, 4117, 8967, 295, 2182, 9656, 1622], "avg_logprob": -0.1725352083293485, "compression_ratio": 1.4205607476635513, "no_speech_prob": 2.5033950805664062e-06, "words": [{"start": 598.84, "end": 599.02, "word": "في", "probability": 0.876953125}, {"start": 599.02, "end": 599.44, "word": " منطقة", "probability": 0.9894205729166666}, {"start": 599.44, "end": 599.64, "word": " الـ", "probability": 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0.931640625}, {"start": 606.7, "end": 607.08, "word": " in", "probability": 0.96142578125}, {"start": 607.08, "end": 607.74, "word": " generating", "probability": 0.91943359375}, {"start": 607.74, "end": 608.02, "word": " a", "probability": 0.9892578125}, {"start": 608.02, "end": 608.24, "word": " color", "probability": 0.5849609375}, {"start": 608.24, "end": 608.56, "word": " red", "probability": 0.7431640625}, {"start": 608.56, "end": 608.9, "word": " purple", "probability": 0.498046875}, {"start": 608.9, "end": 609.3, "word": " line", "probability": 0.9443359375}, {"start": 609.3, "end": 609.76, "word": " حيطلع", "probability": 0.8360595703125}, {"start": 609.76, "end": 610.1, "word": " عندي", "probability": 0.809814453125}, {"start": 610.1, "end": 610.86, "word": " لون", "probability": 0.96875}, {"start": 610.86, "end": 611.5, "word": " في", "probability": 0.927734375}, {"start": 611.5, "end": 611.84, "word": " هذا", "probability": 0.95751953125}, {"start": 611.84, "end": 612.48, "word": " المكان", "probability": 0.99462890625}, {"start": 612.48, "end": 614.72, "word": " هذا", "probability": 0.87646484375}, {"start": 614.72, "end": 615.0, "word": " طبعا", "probability": 0.955322265625}, {"start": 615.0, "end": 615.12, "word": " اللي", "probability": 0.959716796875}, {"start": 615.12, "end": 615.58, "word": " سمناه", "probability": 0.8475341796875}, {"start": 615.58, "end": 615.82, "word": " test", "probability": 0.5263671875}, {"start": 615.82, "end": 616.56, "word": " line", "probability": 0.9267578125}, {"start": 616.56, "end": 621.74, "word": " طيب", "probability": 0.9803059895833334}, {"start": 621.74, "end": 622.32, "word": " الآن", "probability": 0.6787109375}, {"start": 622.32, "end": 622.92, "word": " بقولك", "probability": 0.98095703125}, {"start": 622.92, "end": 623.46, "word": " appearance", "probability": 0.775390625}, {"start": 623.46, "end": 624.02, "word": " of", "probability": 0.982421875}, {"start": 624.02, "end": 624.3, "word": " red", 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"end": 631.67, "word": " membrane", "probability": 0.85693359375}, {"start": 631.67, "end": 632.99, "word": " indicates", "probability": 0.380615234375}, {"start": 632.99, "end": 633.45, "word": " the", "probability": 0.87060546875}, {"start": 633.45, "end": 633.79, "word": " presence", "probability": 0.966796875}, {"start": 633.79, "end": 634.05, "word": " of", "probability": 0.98095703125}, {"start": 634.05, "end": 634.51, "word": " antigen", "probability": 0.8828125}, {"start": 634.51, "end": 634.71, "word": " in", "probability": 0.87158203125}, {"start": 634.71, "end": 635.19, "word": " interest", "probability": 0.7998046875}, {"start": 635.19, "end": 635.39, "word": " in", "probability": 0.90185546875}, {"start": 635.39, "end": 635.61, "word": " the", "probability": 0.90966796875}, {"start": 635.61, "end": 635.91, "word": " sample", "probability": 0.8671875}, {"start": 635.91, "end": 636.79, "word": ".Since", "probability": 0.6497802734375}, {"start": 636.79, "end": 637.05, "word": " the", "probability": 0.91259765625}, {"start": 637.05, "end": 637.47, "word": " liquid", "probability": 0.9169921875}, {"start": 637.47, "end": 637.73, "word": " of", "probability": 0.91650390625}, {"start": 637.73, "end": 637.95, "word": " the", "probability": 0.90576171875}, {"start": 637.95, "end": 638.31, "word": " sample", "probability": 0.865234375}, {"start": 638.31, "end": 639.47, "word": " migrates", "probability": 0.784912109375}, {"start": 639.47, "end": 639.69, "word": " through", "probability": 0.89404296875}, {"start": 639.69, "end": 639.93, "word": " the", "probability": 0.90625}, {"start": 639.93, "end": 640.31, "word": " membrane", "probability": 0.8330078125}, {"start": 640.31, "end": 640.59, "word": " very", "probability": 0.8564453125}, {"start": 640.59, "end": 640.99, "word": " fast,", "probability": 0.8583984375}, {"start": 641.11, "end": 641.19, "word": " it", "probability": 0.80908203125}, {"start": 641.19, "end": 641.51, "word": " makes", "probability": 0.7724609375}, {"start": 641.51, "end": 642.01, "word": " possible", "probability": 0.5419921875}, {"start": 642.01, "end": 642.19, "word": " to", "probability": 0.96923828125}, {"start": 642.19, "end": 642.47, "word": " detect", "probability": 0.97216796875}, {"start": 642.47, "end": 642.69, "word": " the", "probability": 0.9111328125}, {"start": 642.69, "end": 642.99, "word": " presence", "probability": 0.97412109375}, {"start": 642.99, "end": 643.23, "word": " or", "probability": 0.9443359375}, {"start": 643.23, "end": 643.53, "word": " absence", "probability": 0.97998046875}, {"start": 643.53, "end": 643.77, "word": " of", "probability": 0.974609375}, {"start": 643.77, "end": 644.11, "word": " antigen", "probability": 0.9150390625}, {"start": 644.11, "end": 644.35, "word": " within", "probability": 0.923828125}, {"start": 644.35, "end": 644.73, "word": " 15", "probability": 0.76123046875}, {"start": 644.73, "end": 645.15, "word": " minutes", "probability": 0.86328125}, {"start": 645.15, "end": 645.41, "word": ".اش", "probability": 0.33843994140625}, {"start": 645.41, "end": 646.75, "word": " يعني؟قولك", "probability": 0.74833984375}, {"start": 646.75, "end": 646.87, "word": " اللي", "probability": 0.84033203125}, {"start": 646.87, "end": 647.19, "word": " liquid", "probability": 0.53271484375}, {"start": 647.19, "end": 647.43, "word": " لل", "probability": 0.76806640625}, {"start": 647.43, "end": 647.79, "word": " sample", "probability": 0.486328125}, {"start": 647.79, "end": 648.15, "word": " اللي", "probability": 0.916259765625}, {"start": 648.15, "end": 648.31, "word": " أنا", "probability": 0.6474609375}, {"start": 648.31, "end": 648.85, "word": " أضفتها", "probability": 0.83837890625}, {"start": 648.85, "end": 648.97, "word": " ال", "probability": 0.619140625}, {"start": 648.97, "end": 649.19, "word": " sample", "probability": 0.9052734375}, {"start": 649.19, "end": 649.37, "word": " ما", "probability": 0.90185546875}, {"start": 649.37, "end": 649.49, "word": " هي", "probability": 0.654296875}, {"start": 649.49, "end": 649.79, "word": " liquid", "probability": 0.89794921875}, {"start": 649.79, "end": 650.17, "word": " وفيها", "probability": 0.8527018229166666}, {"start": 650.17, "end": 650.55, "word": " سائل", "probability": 0.9275716145833334}, {"start": 650.55, "end": 651.03, "word": " السائل", "probability": 0.8640950520833334}, {"start": 651.03, "end": 651.23, "word": " هذا", "probability": 0.27978515625}, {"start": 651.23, "end": 651.99, "word": " هيعمل", "probability": 0.9677734375}, {"start": 651.99, "end": 652.51, "word": " migration", "probability": 0.8984375}, {"start": 652.51, "end": 652.99, "word": " بسرعة", "probability": 0.98193359375}, {"start": 652.99, "end": 654.13, "word": " كبيرة", "probability": 0.9278971354166666}, {"start": 654.13, "end": 654.49, "word": " يعني", "probability": 0.917236328125}], "temperature": 1.0}, {"id": 24, "seek": 68322, "start": 654.9, "end": 683.22, "text": "عبر الـ Strip فبالتالي عملية الـ detection هتكون كتير سريعة ممكن خلال 15 دقيقة بالكتير أاخد النتيجة An immunochromatographic unit is completed by attaching the sample pad at the end of the membrane شو يعني؟ هلقيت ال immunochromatographic strip أو unit اللي احنا شفناه طبعا بيكون dry بيكون جاف ومش هيصير فيه أي reaction طالما هو جاف", "tokens": [3615, 26890, 2423, 39184, 745, 8400, 6156, 3555, 6027, 2655, 6027, 1829, 6225, 42213, 10632, 2423, 39184, 17784, 8032, 2655, 30544, 9122, 2655, 13546, 8608, 16572, 27884, 3714, 43020, 16490, 1211, 6027, 2119, 11778, 38436, 28671, 20666, 4117, 2655, 13546, 5551, 47283, 3215, 28239, 31371, 7435, 3660, 1107, 13154, 8997, 4397, 267, 12295, 4985, 307, 7365, 538, 39074, 264, 6889, 6887, 412, 264, 917, 295, 264, 19651, 13412, 2407, 37495, 22653, 22807, 8032, 1211, 4587, 36081, 2423, 13154, 8997, 4397, 267, 12295, 12828, 34051, 4985, 13672, 1829, 1975, 5016, 8315, 13412, 5172, 8315, 3224, 23032, 3555, 3615, 995, 4724, 1829, 30544, 4016, 4724, 1829, 30544, 10874, 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"end": 660.14, "word": " سريعة", "probability": 0.9479166666666666}, {"start": 660.14, "end": 661.4, "word": " ممكن", "probability": 0.977294921875}, {"start": 661.4, "end": 661.86, "word": " خلال", "probability": 0.99609375}, {"start": 661.86, "end": 662.26, "word": " 15", "probability": 0.73681640625}, {"start": 662.26, "end": 663.1, "word": " دقيقة", "probability": 0.9612630208333334}, {"start": 663.1, "end": 663.7, "word": " بالكتير", "probability": 0.96044921875}, {"start": 663.7, "end": 664.18, "word": " أاخد", "probability": 0.7449544270833334}, {"start": 664.18, "end": 664.84, "word": " النتيجة", "probability": 0.93798828125}, {"start": 664.84, "end": 665.74, "word": " An", "probability": 0.20068359375}, {"start": 665.74, "end": 667.0, "word": " immunochromatographic", "probability": 0.87001953125}, {"start": 667.0, "end": 667.44, "word": " unit", "probability": 0.9638671875}, {"start": 667.44, "end": 667.96, "word": " is", "probability": 0.9326171875}, {"start": 667.96, "end": 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0.805419921875}, {"start": 672.02, "end": 673.06, "word": " يعني؟", "probability": 0.7918294270833334}, {"start": 673.06, "end": 673.38, "word": " هلقيت", "probability": 0.7540283203125}, {"start": 673.38, "end": 673.5, "word": " ال", "probability": 0.96435546875}, {"start": 673.5, "end": 674.64, "word": " immunochromatographic", "probability": 0.95009765625}, {"start": 674.64, "end": 675.14, "word": " strip", "probability": 0.6435546875}, {"start": 675.14, "end": 675.44, "word": " أو", "probability": 0.94482421875}, {"start": 675.44, "end": 675.84, "word": " unit", "probability": 0.96875}, {"start": 675.84, "end": 676.24, "word": " اللي", "probability": 0.969970703125}, {"start": 676.24, "end": 676.66, "word": " احنا", "probability": 0.777099609375}, {"start": 676.66, "end": 677.16, "word": " شفناه", "probability": 0.85760498046875}, {"start": 677.16, "end": 677.46, "word": " طبعا", "probability": 0.983154296875}, {"start": 677.46, "end": 677.8, "word": " بيكون", "probability": 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الـ Conjugate هذا المفروض يصير له Release بسرعة وبشكل كامل يعني كل الـ Conjugate ينحل ويمشي مع الـ Sample تمام؟ مجرد ما أضيف الـ Sample المفروض الـ Conjugate يصير له Rapid Release Allows for interaction between the detector agent in the conjugate and the target in the sample", "tokens": [1211, 19452, 37893, 44650, 5172, 995, 30241, 3660, 20449, 40294, 4724, 5016, 1829, 12984, 36145, 3224, 4724, 2304, 7435, 2288, 3215, 19446, 5551, 5016, 9566, 2423, 39184, 4832, 781, 36145, 2423, 39184, 2656, 42068, 473, 23758, 9673, 5172, 32887, 11242, 7251, 9381, 13546, 46740, 34278, 4724, 3794, 2288, 27884, 46599, 8592, 28820, 9122, 10943, 1211, 37495, 22653, 28242, 2423, 39184, 2656, 42068, 473, 7251, 1863, 5016, 1211, 4032, 32640, 8592, 1829, 20449, 2423, 39184, 4832, 781, 46811, 10943, 22807, 3714, 7435, 2288, 3215, 19446, 5551, 11242, 33911, 2423, 39184, 4832, 781, 9673, 5172, 32887, 11242, 2423, 39184, 2656, 42068, 473, 7251, 9381, 13546, 46740, 44580, 34278, 1057, 1509, 337, 9285, 1296, 264, 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إذا", "probability": 0.979248046875}, {"start": 1671.59, "end": 1671.95, "word": " كانت", "probability": 0.993408203125}, {"start": 1671.95, "end": 1672.75, "word": " النتيجة", "probability": 0.980224609375}, {"start": 1672.75, "end": 1673.21, "word": " positive", "probability": 0.89892578125}, {"start": 1673.21, "end": 1673.69, "word": " بظهر", "probability": 0.9208984375}, {"start": 1673.69, "end": 1674.05, "word": " معاكي", "probability": 0.9542236328125}, {"start": 1674.05, "end": 1674.31, "word": " خط", "probability": 0.994384765625}, {"start": 1674.31, "end": 1674.83, "word": " واحد", "probability": 0.954833984375}], "temperature": 1.0}, {"id": 61, "seek": 170220, "start": 1675.18, "end": 1702.2, "text": "إذا كانت negative حيظهر معاكي خطأ a test is positive when a sample with target analyte is loaded on the sample application bed and flow through the strip to produce a colored line only in the control zone يعني ال positive بس ال control بيعطينا line on the other hand a negative test occurs when the sample with or without target analyte is loaded on the sample application bed and flow through", "tokens": [28814, 15730, 25961, 2655, 3671, 11331, 1829, 19913, 3224, 2288, 20449, 995, 4117, 1829, 16490, 9566, 10721, 257, 1500, 307, 3353, 562, 257, 6889, 365, 3779, 6459, 975, 307, 13210, 322, 264, 6889, 3861, 2901, 293, 3095, 807, 264, 12828, 281, 5258, 257, 14332, 1622, 787, 294, 264, 1969, 6668, 37495, 22653, 2423, 3353, 4724, 3794, 2423, 1969, 4724, 40228, 9566, 1829, 8315, 1622, 322, 264, 661, 1011, 257, 3671, 1500, 11843, 562, 264, 6889, 365, 420, 1553, 3779, 6459, 975, 307, 13210, 322, 264, 6889, 3861, 2901, 293, 3095, 807], "avg_logprob": -0.1719599132952483, "compression_ratio": 1.8143459915611815, "no_speech_prob": 8.940696716308594e-07, "words": [{"start": 1675.18, "end": 1675.56, "word": "إذا", "probability": 0.95458984375}, {"start": 1675.56, "end": 1675.98, "word": " كانت", "probability": 0.988525390625}, {"start": 1675.98, "end": 1676.28, "word": " 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principle بتاعةك؟ طبعا هذا هو الـ Strip اللي إحنا شوفناه قبل بشوية فيه اختلاف بسيط بس الاختلاف هذا أنه عند ال sample line أو ال test line الـ antibody الموجود already مرتبط مع أنتجن تمام؟ الـ antigen هذا", "tokens": [6027, 39184, 745, 8400, 281, 5258, 14332, 1622, 294, 1293, 1969, 6668, 293, 4997, 6668, 37495, 22653, 8978, 2423, 39184, 46326, 4724, 40228, 9566, 1829, 16490, 9566, 4032, 41185, 2423, 39184, 43230, 4724, 40228, 9566, 1829, 16490, 9566, 37495, 22653, 23032, 3555, 11933, 1829, 8592, 39896, 2423, 39184, 8665, 39894, 995, 27884, 4117, 22807, 23032, 3555, 3615, 995, 23758, 31439, 2423, 39184, 745, 8400, 13672, 1829, 11933, 5016, 8315, 13412, 38688, 8315, 3224, 12174, 36150, 4724, 8592, 2407, 10632, 8978, 3224, 1975, 46456, 15040, 5172, 4724, 3794, 1829, 9566, 4724, 3794, 2423, 47283, 2655, 15040, 5172, 23758, 14739, 3224, 43242, 2423, 6889, 1622, 34051, 2423, 1500, 1622, 2423, 39184, 34507, 9673, 29245, 23328, 1217, 3714, 43500, 3555, 9566, 20449, 14739, 2655, 7435, 1863, 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"probability": 0.1578369140625}, {"start": 1929.93, "end": 1930.39, "word": " present", "probability": 0.9208984375}, {"start": 1930.39, "end": 1930.69, "word": " in", "probability": 0.96630859375}, {"start": 1930.69, "end": 1930.97, "word": " such", "probability": 0.95947265625}, {"start": 1930.97, "end": 1931.31, "word": " low", "probability": 0.9404296875}, {"start": 1931.31, "end": 1931.83, "word": " quantity", "probability": 0.95849609375}, {"start": 1931.83, "end": 1932.49, "word": " that", "probability": 0.7578125}, {"start": 1932.49, "end": 1932.83, "word": " some", "probability": 0.81494140625}, {"start": 1932.83, "end": 1933.29, "word": " sites", "probability": 0.93603515625}, {"start": 1933.29, "end": 1933.55, "word": " of", "probability": 0.97412109375}, {"start": 1933.55, "end": 1933.83, "word": " label", "probability": 0.8642578125}, {"start": 1933.83, "end": 1934.39, "word": " antibody", "probability": 0.8076171875}, {"start": 1934.39, "end": 1934.83, "word": " 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"end": 1940.97, "word": " لازالت", "probability": 0.9111328125}, {"start": 1940.97, "end": 1941.47, "word": " الأماكن", "probability": 0.99462890625}, {"start": 1941.47, "end": 1941.65, "word": " اللي", "probability": 0.970703125}, {"start": 1941.65, "end": 1941.91, "word": " فيه", "probability": 0.94091796875}, {"start": 1941.91, "end": 1942.39, "word": " شاغرة", "probability": 0.9583740234375}, {"start": 1942.39, "end": 1942.61, "word": " و", "probability": 0.48974609375}, {"start": 1942.61, "end": 1943.13, "word": " بالإمكان", "probability": 0.8363037109375}, {"start": 1943.13, "end": 1943.43, "word": " أنه", "probability": 0.698974609375}, {"start": 1943.43, "end": 1943.91, "word": " يرتبط", "probability": 0.9927978515625}, {"start": 1943.91, "end": 1944.19, "word": " يعني", "probability": 0.943603515625}, {"start": 1944.19, "end": 1944.67, "word": " بظهر", "probability": 0.861083984375}, {"start": 1944.67, "end": 1944.95, "word": " عندى", "probability": 0.589599609375}, {"start": 1944.95, "end": 1945.19, "word": " اللون", "probability": 0.923828125}, {"start": 1945.19, "end": 1945.39, "word": " لو", "probability": 0.98779296875}, {"start": 1945.39, "end": 1945.59, "word": " كان", "probability": 0.9912109375}, {"start": 1945.59, "end": 1946.39, "word": " التركيز", "probability": 0.935302734375}, {"start": 1946.39, "end": 1946.67, "word": " كتير", "probability": 0.8758138020833334}, {"start": 1946.67, "end": 1947.09, "word": " خفيف", "probability": 0.8994140625}, {"start": 1947.09, "end": 1947.81, "word": " أو", "probability": 0.9775390625}, {"start": 1947.81, "end": 1948.25, "word": " كان", "probability": 0.90576171875}, {"start": 1948.25, "end": 1948.73, "word": " مافيش", "probability": 0.9296875}, {"start": 1948.73, "end": 1949.03, "word": " عندى", "probability": 0.74658203125}, {"start": 1949.03, "end": 1949.31, "word": " أصلا", "probability": 0.8976236979166666}, {"start": 1949.31, "end": 1949.87, "word": " Antigen", "probability": 0.6544189453125}, {"start": 1949.87, "end": 1950.35, "word": " خالص", "probability": 0.9978841145833334}], "temperature": 1.0}, {"id": 71, "seek": 197276, "start": 1950.7, "end": 1972.76, "text": "«الأنتجين في المحلول المثالي» و«الشخص اللذي قام بعمل محاولة في تجارة قمبيت للتعامل مع مجموعات تسمى Conjugate» «الشخص اللذي قام بعمل محاولة للتعامل مع مجموعات تسمى Conjugate» «الشخص اللذي قام بعمل محاولة للتعامل مع مجموعات تسمى Conjugate» «الشخص اللذي قام بعمل محاولة للتعامل مع مجموعات تسمى Conjugate» «الشخص اللذي قام بعمل محاولة للتعامل مع مجموعات تسمى Conjugate» «الشخص اللذي قام بعمل محاولة", "tokens": [36784, 6027, 33456, 2655, 7435, 9957, 8978, 9673, 5016, 1211, 12610, 9673, 12984, 6027, 1829, 5933, 4032, 36784, 6027, 8592, 9778, 9381, 13672, 8848, 1829, 12174, 10943, 4724, 25957, 1211, 3714, 5016, 995, 12610, 3660, 8978, 6055, 7435, 9640, 3660, 12174, 2304, 21292, 2655, 24976, 2655, 3615, 10943, 1211, 20449, 3714, 7435, 2304, 45367, 9307, 6055, 38251, 7578, 2656, 42068, 473, 5933, 4657, 6027, 8592, 9778, 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"avg_logprob": -0.2997222137451172, "compression_ratio": 4.546666666666667, "no_speech_prob": 7.152557373046875e-07, "words": [{"start": 1950.7, "end": 1951.22, "word": "«الأنتجين", "probability": 0.6140950520833334}, {"start": 1951.22, "end": 1951.42, "word": " في", "probability": 0.80419921875}, {"start": 1951.42, "end": 1952.0, "word": " المحلول", "probability": 0.3057708740234375}, {"start": 1952.0, "end": 1952.5, "word": " المثالي»", "probability": 0.53876953125}, {"start": 1952.5, "end": 1954.36, "word": " و«الشخص", "probability": 0.6694742838541666}, {"start": 1954.36, "end": 1955.06, "word": " اللذي", "probability": 0.5070393880208334}, {"start": 1955.06, "end": 1955.3, "word": " قام", "probability": 0.3311767578125}, {"start": 1955.3, "end": 1955.3, "word": " بعمل", "probability": 0.5482584635416666}, {"start": 1955.3, "end": 1955.9, "word": " محاولة", "probability": 0.569287109375}, {"start": 1955.9, "end": 1956.06, "word": " في", "probability": 0.224365234375}, {"start": 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محاولة", "probability": 0.98212890625}, {"start": 1961.74, "end": 1961.8, "word": " للتعامل", "probability": 0.8325439453125}, {"start": 1961.8, "end": 1963.04, "word": " مع", "probability": 0.8984375}, {"start": 1963.04, "end": 1963.5, "word": " مجموعات", "probability": 0.90966796875}, {"start": 1963.5, "end": 1963.5, "word": " تسمى", "probability": 0.92578125}, {"start": 1963.5, "end": 1964.08, "word": " Conjugate»", "probability": 0.9837646484375}, {"start": 1964.08, "end": 1964.1, "word": " «الشخص", "probability": 0.8384765625}, {"start": 1964.1, "end": 1964.1, "word": " اللذي", "probability": 0.9923502604166666}, {"start": 1964.1, "end": 1964.1, "word": " قام", "probability": 0.986083984375}, {"start": 1964.1, "end": 1964.1, "word": " بعمل", "probability": 0.9720052083333334}, {"start": 1964.1, "end": 1964.1, "word": " محاولة", "probability": 0.9857421875}, {"start": 1964.1, "end": 1964.1, "word": " للتعامل", "probability": 0.92353515625}, {"start": 1964.1, "end": 1964.1, "word": " مع", "probability": 0.98486328125}, {"start": 1964.1, "end": 1964.16, "word": " مجموعات", "probability": 0.9630859375}, {"start": 1964.16, "end": 1964.2, "word": " تسمى", "probability": 0.9440104166666666}, {"start": 1964.2, "end": 1964.48, "word": " Conjugate»", "probability": 0.9859619140625}, {"start": 1964.48, "end": 1965.48, "word": " «الشخص", "probability": 0.87978515625}, {"start": 1965.48, "end": 1965.58, "word": " اللذي", "probability": 0.9918619791666666}, {"start": 1965.58, "end": 1965.78, "word": " قام", "probability": 0.988037109375}, {"start": 1965.78, "end": 1965.78, "word": " بعمل", "probability": 0.9765625}, {"start": 1965.78, "end": 1965.94, "word": " محاولة", "probability": 0.987109375}, {"start": 1965.94, "end": 1966.12, "word": " للتعامل", "probability": 0.96669921875}, {"start": 1966.12, "end": 1966.24, "word": " مع", "probability": 0.99365234375}, {"start": 1966.24, "end": 1966.3, "word": " مجموعات", "probability": 0.95908203125}, {"start": 1966.3, "end": 1966.6, "word": " تسمى", "probability": 0.9054361979166666}, {"start": 1966.6, "end": 1967.98, "word": " Conjugate»", "probability": 0.98583984375}, {"start": 1967.98, "end": 1968.62, "word": " «الشخص", "probability": 0.927734375}, {"start": 1968.62, "end": 1968.62, "word": " اللذي", "probability": 0.9903971354166666}, {"start": 1968.62, "end": 1968.62, "word": " قام", "probability": 0.989013671875}, {"start": 1968.62, "end": 1969.9, "word": " بعمل", "probability": 0.9807942708333334}, {"start": 1969.9, "end": 1971.12, "word": " محاولة", "probability": 0.9892578125}, {"start": 1971.12, "end": 1971.6, "word": " للتعامل", "probability": 0.980859375}, {"start": 1971.6, "end": 1971.6, "word": " مع", "probability": 0.99609375}, {"start": 1971.6, "end": 1972.18, "word": " مجموعات", "probability": 0.96455078125}, {"start": 1972.18, "end": 1972.18, "word": " تسمى", "probability": 0.8538411458333334}, {"start": 1972.18, "end": 1972.76, "word": " Conjugate»", "probability": 0.985595703125}, {"start": 1972.76, "end": 1972.76, "word": " «الشخص", "probability": 0.94873046875}, {"start": 1972.76, "end": 1972.76, "word": " اللذي", "probability": 0.9759114583333334}, {"start": 1972.76, "end": 1972.76, "word": " قام", "probability": 0.989501953125}, {"start": 1972.76, "end": 1972.76, "word": " بعمل", "probability": 0.9811197916666666}, {"start": 1972.76, "end": 1972.76, "word": " محاولة", "probability": 0.99150390625}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1973.2085625, "duration_after_vad": 1920.032499999996}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/peSzn1o5k78_raw.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/peSzn1o5k78_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..9931bbfc543c4e2a7fa353804a0844d33f3fee9d
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/peSzn1o5k78_raw.srt
@@ -0,0 +1,1908 @@
+1
+00:00:02,090 --> 00:00:05,990
+بسم الله الرحمن الرحيم راح نتحدث اليوم إن شاء الله
+
+2
+00:00:05,990 --> 00:00:12,290
+رب العالمين في موضوع بسيط وتطبيقه كتير سهل والكل
+
+3
+00:00:12,290 --> 00:00:17,390
+فينا تقريبا شافه أو بيشوفه اللي هو ال reaction
+
+4
+00:00:17,390 --> 00:00:22,250
+اللي بتم باستخدام strip هذا بسميه immuno أو بعتمد
+
+5
+00:00:22,250 --> 00:00:27,670
+على ال principle اللي هي immunochromatographyالـ
+
+6
+00:00:27,670 --> 00:00:31,610
+Immunochromatography فحص بسيط بيعتمد immunological
+
+7
+00:00:31,610 --> 00:00:35,170
+reaction مع chromatographic separation يعني التنين
+
+8
+00:00:35,170 --> 00:00:40,450
+مع بعض بيسيروا في نفس الوقت وبيعطي نتائج جيدة ال
+
+9
+00:00:40,450 --> 00:00:44,470
+Immunochromatography له اسم تاني اللي هو lateral
+
+10
+00:00:44,470 --> 00:00:49,890
+effluent أو dipstick له أشكال كتيرة زي ما أنتوا
+
+11
+00:00:49,890 --> 00:00:55,530
+شايفين يعني في أشكال متعددة منههو عبارة عن شغلة
+
+12
+00:00:55,530 --> 00:00:59,170
+بسيطة كتير simple device intended to detect the
+
+13
+00:00:59,170 --> 00:01:03,090
+presence or absence of an analyte يعني هو بيحدد
+
+14
+00:01:03,090 --> 00:01:07,290
+وجود analyte من عدمه يعني فعليًا أنا بكون بدور على
+
+15
+00:01:07,290 --> 00:01:10,890
+شغلة معينة بدي أشوف هل الشغلة هذه موجودة ولا مش
+
+16
+00:01:10,890 --> 00:01:16,690
+موجودة بفحص بسيط وسهل وماياخدش مني وقت كتير بعدين
+
+17
+00:01:16,690 --> 00:01:20,890
+ما بحتاج أجهزة معقدة عشان أقرأ النتيجة هو مجرد
+
+18
+00:01:21,340 --> 00:01:24,980
+ستريب بسيط بحط عليه العينة وبتظهر النتيجة على شكل
+
+19
+00:01:24,980 --> 00:01:31,460
+خط ملون a widely spread and well-known application
+
+20
+00:01:31,460 --> 00:01:35,000
+is «home pregnancy test» يعني هو من التطبيقات
+
+21
+00:01:35,000 --> 00:01:39,320
+الشائعة اللي هو الـ «home pregnancy test» ممكن
+
+22
+00:01:39,320 --> 00:01:43,820
+عادي ينشره من الصيدلية وسعره رخيص وأي ست في البيت
+
+23
+00:01:43,820 --> 00:01:47,320
+ممكن تعمل pregnancy test بهذه الطريقة وتشوف
+
+24
+00:01:47,320 --> 00:01:51,750
+النتيجة إذا كانت positive أو negative طبعاًهو في
+
+25
+00:01:51,750 --> 00:01:54,650
+البداية عبارة عن qualitative test ما بيعطيني أي
+
+26
+00:01:54,650 --> 00:01:59,370
+أرقام أو أي نتائج رقمية وإنما بيعطيني positive
+
+27
+00:01:59,370 --> 00:02:05,770
+نتيجة ولا negative طيب خلينا نشوف إيش هي تركيبة ال
+
+28
+00:02:05,770 --> 00:02:09,410
+strip بغض النظر عن الشكل الخارجي له لو جينا نشوف
+
+29
+00:02:09,410 --> 00:02:13,950
+من الداخل من إيش بتركب في بداية المكان اللي أنا
+
+30
+00:02:13,950 --> 00:02:17,610
+بحط عليه ال sample طبعا بتتبع التعليمات جيدا حسب
+
+31
+00:02:17,610 --> 00:02:20,760
+ما بيقولي حجم ال sampleأو نوعها أو إذا بدها
+
+32
+00:02:20,760 --> 00:02:25,120
+dilution أو ما بدها dilution الآن إذا المكان الأول
+
+33
+00:02:25,120 --> 00:02:28,160
+اللي هو ال sample bad بحط عليه إيش ال sample
+
+34
+00:02:28,160 --> 00:02:32,260
+المنطقة التانية أو الحاجة التانية المهمة اللي هي
+
+35
+00:02:32,260 --> 00:02:36,800
+بيسموها conjugate bad إيش ال conjugate bad هذا
+
+36
+00:02:36,800 --> 00:02:41,780
+المكان اللي فيه ال detector كيف يعني ال detector
+
+37
+00:02:41,780 --> 00:02:45,160
+يعني على سبيل المثال أنا بدور على antigen هنا
+
+38
+00:02:45,160 --> 00:02:48,380
+هيكون في labelled antibody يرتبط مع هذا ال antigen
+
+39
+00:02:48,380 --> 00:02:53,170
+تمامإذن Conjugate VAD Sample Meets Detection
+
+40
+00:02:53,170 --> 00:02:56,090
+Reagent هتلتقي الـ Sample مع الـ Reagent اللي
+
+41
+00:02:56,090 --> 00:03:01,130
+هيعمللها Detection بعد هيك في عندي Nitrocellulose
+
+42
+00:03:01,130 --> 00:03:05,490
+Membrane بياخد مسافة طويلة الـ Nitrocellulose
+
+43
+00:03:05,490 --> 00:03:10,470
+Membrane هذا عادة يكون فيه شغلتين مهمات الشغل
+
+44
+00:03:10,470 --> 00:03:19,310
+الأولى هذه يعني بيكون مثبت عليها مادة بتروح ترتبط
+
+45
+00:03:19,760 --> 00:03:24,440
+مع الـ Complex تاع الـ Antigen Antibody إذا تكون
+
+46
+00:03:24,440 --> 00:03:28,820
+فهذه يعني إذا أعطتني هنا لون بتدل على إن العينة
+
+47
+00:03:28,820 --> 00:03:31,160
+Positive والـ Antigen اللي أنا بدور عليه موجود
+
+48
+00:03:31,160 --> 00:03:33,720
+طبعا التفاصيل هنفهمها لقدام شوية بس أنا بحكي على
+
+49
+00:03:33,720 --> 00:03:38,880
+الـ Structure الآن إذا الخط الأول بتدل على الـ
+
+50
+00:03:38,880 --> 00:03:41,620
+Sample إذا كانت موجودة وظهر عندي الخط في هذا
+
+51
+00:03:41,620 --> 00:03:44,900
+المكان معنى الكلام إن الـ Sample اللي أنا بدور
+
+52
+00:03:44,900 --> 00:03:50,020
+عليها ارتبطت في هذا المكان وأعطتني لونالخط التاني
+
+53
+00:03:50,020 --> 00:03:54,080
+برضه عن Nitrocellulose paper هذا بيسموه الـ
+
+54
+00:03:54,080 --> 00:03:57,300
+control line ال control line هذا لازم يعطيني
+
+55
+00:03:57,300 --> 00:04:01,220
+positive دايما لو أعطاني negative معنى الكلام أنه
+
+56
+00:04:01,220 --> 00:04:05,540
+الفحص invalid بمعنى أن هذا الفحص لازم يعطيني على
+
+57
+00:04:05,540 --> 00:04:10,900
+الأقل ال control line positive لكن لو كانت العينة
+
+58
+00:04:10,900 --> 00:04:14,340
+positive فعليا هتعطيني خطين إذا خط واحد يعني
+
+59
+00:04:14,340 --> 00:04:18,160
+negative وخطين يعني positive ولا خطيعني الـ Strip
+
+60
+00:04:18,160 --> 00:04:22,720
+خربان، تمام؟ في بالنهاية، في عندي Absorbent Paper
+
+61
+00:04:22,720 --> 00:04:27,240
+في عندي منطقة للامتصاص هذه الهدف منها تمتص أي
+
+62
+00:04:27,240 --> 00:04:31,340
+زوائد من السوائل بحيث إن السوائل هذه ما ترجع هك
+
+63
+00:04:31,340 --> 00:04:37,420
+باتجاه عكسي وتخرب عندي الـReagent
+
+64
+00:04:37,420 --> 00:04:42,220
+أو الـLines اللي اتكونت طيب خليني نشوف بعد هيك الـ
+
+65
+00:04:42,220 --> 00:04:47,170
+Principle تحت الفحص بالتفصيل بدايةإحنا إذا كنتوا
+
+66
+00:04:47,170 --> 00:04:50,810
+فاكرين في عندي مكان بحط فيه الـ Sample وفي مكان
+
+67
+00:04:50,810 --> 00:04:54,250
+بيصير فيه التفاعل، تفاعل الـ Sample مع الـ
+
+68
+00:04:54,250 --> 00:04:57,970
+Detector الـ Antibody اللي أنا بدي .. يعني بدي
+
+69
+00:04:57,970 --> 00:04:59,870
+إياه يتفاعل مع الـ Antigen اللي موجود في الـ
+
+70
+00:04:59,870 --> 00:05:05,030
+Sample إذا أول حاجة، في عندي الـ Sample Bad بعد
+
+71
+00:05:05,030 --> 00:05:09,690
+هيك، هيكون في عندي Ash Antibody، الـ Antibody هذا
+
+72
+00:05:09,690 --> 00:05:14,700
+labelled Bicolloidal Goldشايفين؟ هذا الـ Antibody
+
+73
+00:05:14,700 --> 00:05:19,080
+labelled بكلية دا الـ Gold موجود على الـ «سلاي»
+
+74
+00:05:19,080 --> 00:05:24,240
+على الـ «ستريب» في هذا المكان حلقات لما أنا بحط
+
+75
+00:05:24,240 --> 00:05:27,700
+الـ «سامبل» هتبدأش الـ «سامبل» تمشي بهذا الاتجاه
+
+76
+00:05:27,700 --> 00:05:31,820
+هتقابل الـ Antibody إذا كان الـ Antigen موجود
+
+77
+00:05:31,820 --> 00:05:36,400
+هيصير ارتباط للـ Antigen بالـ Antibody تمام؟ هيصير
+
+78
+00:05:36,400 --> 00:05:40,320
+ارتباط للـ Antigen بالـ Antibody و تظل ماشية إيش
+
+79
+00:05:40,320 --> 00:05:43,810
+أول حاجة هتقابلها؟له الـ Sample Line الخط اللي
+
+80
+00:05:43,810 --> 00:05:46,430
+هيعطيني positive لو كانت الـ Sample Positive
+
+81
+00:05:46,430 --> 00:05:50,510
+هيعطيني لون لو كانت الـ Sample Positive طيب، إيش
+
+82
+00:05:50,510 --> 00:05:54,390
+الـ Sample Line هذا فيه؟ هذا الـ Sample Line فيه
+
+83
+00:05:54,390 --> 00:05:59,470
+Antigen Antibody يعني في عندي كمان Antibody مثبت
+
+84
+00:05:59,470 --> 00:06:02,190
+على الـ Strip على الـ Nitrocellulose Membrane في
+
+85
+00:06:02,190 --> 00:06:06,110
+هذا المكان هلقيت إذا اتكون عندي Antigen Antibody
+
+86
+00:06:06,110 --> 00:06:11,030
+Complex هتلاقي أنه أجل Antigen ارتبط معاكيعلى الـ
+
+87
+00:06:11,030 --> 00:06:14,950
+Antibody المثبت على الـ Strip يعني صار الـ Antigen
+
+88
+00:06:14,950 --> 00:06:18,590
+مرتبط باتنين Antibody واحد اللي مثبت على الـ Strip
+
+89
+00:06:18,590 --> 00:06:23,610
+هذا الهدف منه أنه يمسكه ويثبته في المكان اللي أنا
+
+90
+00:06:23,610 --> 00:06:27,910
+بدي أشوف فيه النتيجة يعني إذا الـ Antigen Antibody
+
+91
+00:06:27,910 --> 00:06:33,870
+Complex تثبت في هذا المكان هلاحظ اللون المميز لـ
+
+92
+00:06:33,870 --> 00:06:37,890
+Colloidal Gold في هذا المكان و هيظهر معايا على شكل
+
+93
+00:06:37,890 --> 00:06:42,450
+الـ Stripإذا ظهر عنده Strip في هذا المكان معنى
+
+94
+00:06:42,450 --> 00:06:46,170
+الكلام إنه كان في عندي Antigen Antibody هنا تفاعله
+
+95
+00:06:46,170 --> 00:06:51,910
+وصار لهم تثبيت على هذا المكان طيب هل إيه بعد ما
+
+96
+00:06:51,910 --> 00:06:54,810
+ثبت الـ Antigen و الـ Antibody على هذا المكان وظهر
+
+97
+00:06:54,810 --> 00:07:00,510
+عندي Line هيظل ماشي ما تبقى من Colloidal Antibody
+
+98
+00:07:00,510 --> 00:07:04,870
+هذا الملون هيظل ماشي في الـ Strip إيش هيقابل؟
+
+99
+00:07:04,870 --> 00:07:09,110
+هيقابل الـ Control Line الـ Control Lineإيش بيكون
+
+100
+00:07:09,110 --> 00:07:15,530
+عليه Antimouse Antibody Antimouse IgG فبالتالي ما
+
+101
+00:07:15,530 --> 00:07:19,770
+تبقى من الـ Antibody هيرتبط مع الـ Antimouse IgG
+
+102
+00:07:19,770 --> 00:07:24,210
+ويعمل عنده Second Line إذا الـ Second Line هذا
+
+103
+00:07:24,210 --> 00:07:28,610
+الهدف منه أشوف إن الـ Antibody هذا اللي بأول خطوة
+
+104
+00:07:28,610 --> 00:07:32,830
+الـ Colloidal Gold Labeled Antibody هل هو شغال
+
+105
+00:07:32,830 --> 00:07:38,060
+بشكل جيد ولا مش شغالالآن سواء العينة Negative أو
+
+106
+00:07:38,060 --> 00:07:43,720
+Positive هذا هيظل ماشي لغاية ما يوصل للـ Control
+
+107
+00:07:43,720 --> 00:07:48,060
+Line طبعاً في العينة الـ Positive هيكون تم استخدام
+
+108
+00:07:48,060 --> 00:07:52,280
+جزء منه للـ Reaction وجزء منه راح يتبقى ويعطيني
+
+109
+00:07:52,280 --> 00:07:56,960
+Line في العينة الـ Negative كله هيظل ماشي للنهاية
+
+110
+00:07:56,960 --> 00:08:02,040
+ويعطيني Line عند الـ Control Line إذا العينة الـ
+
+111
+00:08:02,040 --> 00:08:06,900
+Positive هيطلع عندي خطينالخط الأول نتيجة ارتباط
+
+112
+00:08:06,900 --> 00:08:10,620
+الـ antigen antibody مع الـ antibody المثبت على
+
+113
+00:08:10,620 --> 00:08:15,140
+الشريحة الخط التاني اللي هو ال control line اللي
+
+114
+00:08:15,140 --> 00:08:19,620
+بيصير نتيجة تفاعل الـ colloidal antibody colloidal
+
+115
+00:08:19,620 --> 00:08:25,040
+labelled antibody مع الـ anti IgG طبعا إذا ما ظهر
+
+116
+00:08:25,040 --> 00:08:28,680
+عندي هذا الخط معنى الكلام إن الـ colloidal gold
+
+117
+00:08:28,680 --> 00:08:33,000
+labelled antibody هذا خربان بدي أرمي ال strip
+
+118
+00:08:33,000 --> 00:08:37,270
+وأجيب واحد غيرهتمام؟ إذن هي النتيجة الإيجابية
+
+119
+00:08:37,270 --> 00:08:40,910
+positive النتيجة الـ negative هي أنا حطيت الـ
+
+120
+00:08:40,910 --> 00:08:46,090
+sample bad مافيش الـ antigen فهو هتظلها ماشية مش
+
+121
+00:08:46,090 --> 00:08:50,570
+هيصير ارتباط هيظل الـ colloidal antibody free
+
+122
+00:08:50,570 --> 00:08:55,910
+هيظلوا ماشي مش هيرتبط برضه في مكان الـ sample line
+
+123
+00:08:55,910 --> 00:08:59,790
+اللي هتظهر فيه نتيجة الـ sample هيظلوا ماشي لغاية
+
+124
+00:08:59,790 --> 00:09:03,380
+ما يوصل لخط الـ controlويعطيني لون عند خط الـ
+
+125
+00:09:03,380 --> 00:09:07,540
+control إذا كانت negative حيطلع عندي خط واحد إذا
+
+126
+00:09:07,540 --> 00:09:12,520
+كانت positive حيطلع عندي خطين إذا كان ماطلعش ولا
+
+127
+00:09:12,520 --> 00:09:15,880
+خط معنى الكلام إن ال reagent هذا أو ال strip هذا
+
+128
+00:09:15,880 --> 00:09:20,800
+خربان طيب
+
+129
+00:09:20,800 --> 00:09:23,360
+نشوف الاشي المكتوب principle of
+
+130
+00:09:23,360 --> 00:09:27,060
+immunochromatography kit the liquid sample is
+
+131
+00:09:27,060 --> 00:09:31,690
+dropped on the sample bedالأنتيجين في المجلد يصبح
+
+132
+00:09:31,690 --> 00:09:37,970
+مجلد إميون مع مجلد كولويدالجولد يعني هيعملوا مجلد
+
+133
+00:09:37,970 --> 00:09:41,210
+الانتيجين مع مجلد الانتيجين مجلد الانتيجين يتحرك
+
+134
+00:09:41,210 --> 00:09:47,870
+مع مجلد الليكود اللي هيتحركه على الـStrip نفسه
+
+135
+00:09:47,870 --> 00:09:53,950
+ويصبح مجلد الانتيجين مجلد الليكود اللي هيتحرك مع
+
+136
+00:09:53,950 --> 00:09:56,290
+مجلد اللي هيتحرك مع مجلد اللي هيتحرك مع مجلد اللي
+
+137
+00:09:56,290 --> 00:09:58,330
+هيتحرك مع مجلد اللي هيتحرك مع مجلد اللي هيتحرك مع
+
+138
+00:09:58,840 --> 00:10:03,080
+في منطقة الـ test line followed by forming an
+
+139
+00:10:03,080 --> 00:10:06,240
+immunocomplexes with the immobilized antibody
+
+140
+00:10:06,240 --> 00:10:09,300
+resulting in generating a color red purple line
+
+141
+00:10:09,300 --> 00:10:15,580
+حيطلع عندي لون في هذا المكان هذا طبعا اللي سمناه
+
+142
+00:10:15,580 --> 00:10:21,740
+test line طيب
+
+143
+00:10:21,740 --> 00:10:25,240
+الآن بقولك appearance of red purple line
+
+144
+00:10:28,890 --> 00:10:31,670
+Appearance of red purple line on the membrane
+
+145
+00:10:31,670 --> 00:10:35,390
+indicates the presence of antigen in interest in
+
+146
+00:10:35,390 --> 00:10:39,470
+the sample.Since the liquid of the sample migrates
+
+147
+00:10:39,470 --> 00:10:42,010
+through the membrane very fast, it makes possible
+
+148
+00:10:42,010 --> 00:10:44,110
+to detect the presence or absence of antigen
+
+149
+00:10:44,110 --> 00:10:47,430
+within 15 minutes.اش يعني؟قولك اللي liquid لل
+
+150
+00:10:47,430 --> 00:10:49,790
+sample اللي أنا أضفتها ال sample ما هي liquid
+
+151
+00:10:49,790 --> 00:10:54,130
+وفيها سائل السائل هذا هيعمل migration بسرعة كبيرة
+
+152
+00:10:54,130 --> 00:10:58,760
+يعنيعبر الـ Strip فبالتالي عملية الـ detection
+
+153
+00:10:58,760 --> 00:11:04,180
+هتكون كتير سريعة ممكن خلال 15 دقيقة بالكتير أاخد
+
+154
+00:11:04,180 --> 00:11:08,560
+النتيجة An immunochromatographic unit is completed
+
+155
+00:11:08,560 --> 00:11:11,480
+by attaching the sample pad at the end of the
+
+156
+00:11:11,480 --> 00:11:14,640
+membrane شو يعني؟ هلقيت ال immunochromatographic
+
+157
+00:11:14,640 --> 00:11:18,520
+strip أو unit اللي احنا شفناه طبعا بيكون dry بيكون
+
+158
+00:11:18,520 --> 00:11:24,120
+جاف ومش هيصير فيه أي reaction طالما هو جافأمتى
+
+159
+00:11:24,120 --> 00:11:28,340
+بتعمل مكوناته بيبدأ يشتغل لما أنا أضيف عليه Liquid
+
+160
+00:11:28,340 --> 00:11:31,580
+Media الـ Liquid Media من وين بشيبها؟ من الـ
+
+161
+00:11:31,580 --> 00:11:34,520
+Sample ما هي الـ Sample هتكون مثلا urine أو هتكون
+
+162
+00:11:34,520 --> 00:11:38,480
+Serum أو بلازمة الـ Serum أو البلازمة هتعطيني الـ
+
+163
+00:11:38,480 --> 00:11:42,720
+Fluid أو درجة الـ Hydration المناسبة بحيث أنه
+
+164
+00:11:42,720 --> 00:11:46,870
+اتشغل الـ System هذاويبدأ كل واحد ياخد مكانه
+
+165
+00:11:46,870 --> 00:11:49,230
+الصحيح الـ Antigen يتفاعل مع الـ Antibody والـ
+
+166
+00:11:49,230 --> 00:11:51,690
+Antibody يعمل Fixation للـ Antigen Antibody
+
+167
+00:11:51,690 --> 00:11:56,250
+Complex وتظهر عندي الألوان، إذا الـ Sample الـ
+
+168
+00:11:56,250 --> 00:11:58,670
+Water اللي فيها هو اللي بيكمل الـ System و بمشي ال
+
+169
+00:11:58,670 --> 00:12:01,550
+reaction، مافيش Water، مافيش reaction هاي
+
+170
+00:12:01,550 --> 00:12:05,190
+المكونات، بنرجعها مع بعض، في عندي الـ Sample Bad
+
+171
+00:12:05,190 --> 00:12:09,350
+في عندي الـ Conjugate Bad، Cold Conjugate Bad، في
+
+172
+00:12:09,350 --> 00:12:12,120
+عندي Nitrocelluloseفي عندي test line أو capture
+
+173
+00:12:12,120 --> 00:12:16,200
+line في عندي test line control line عفوا في عندي
+
+174
+00:12:16,200 --> 00:12:23,760
+absorbing pad طيب
+
+175
+00:12:23,760 --> 00:12:28,680
+خلينا نشوف المكونات لل strip هذا كل واحد من
+
+176
+00:12:28,680 --> 00:12:32,500
+المكونات إيش لازم يتوفر فيه خصائص عشان يشتغل
+
+177
+00:12:32,500 --> 00:12:38,620
+بكفاءة عالية الآن بالنسبة لل sample pad أول واحدة
+
+178
+00:12:38,620 --> 00:12:42,320
+ال site of sample applicationفي بعض الأمور أنا
+
+179
+00:12:42,320 --> 00:12:48,200
+لازم أعرفها قبل ما أبدأ أشتغل أول حاجة بدي أعرف أن
+
+180
+00:12:48,200 --> 00:12:54,340
+الـ Sample اللي أنا بحطها هيكون فيها تركيز مختلفة
+
+181
+00:12:54,340 --> 00:12:57,240
+من الـ Analyte يعني مش كل العينات اللي لها نفس
+
+182
+00:12:57,240 --> 00:13:03,260
+التركيز فبالتالي لازم أختار حجم مناسب بحيث أنه
+
+183
+00:13:03,260 --> 00:13:06,880
+يخلص sensitivity لهذا الـ kit أو لهذا الـ strip
+
+184
+00:13:06,880 --> 00:13:11,180
+ممتازةعشان الـ variability يعني أنا بدي في ناس
+
+185
+00:13:11,180 --> 00:13:14,740
+بيبقى التركيز عندهم كتير قليل للـ antigen فأنا
+
+186
+00:13:14,740 --> 00:13:19,300
+ممكن من خلال حجم معين لل sample أسمح لل kit أو لل
+
+187
+00:13:19,300 --> 00:13:23,640
+strip أنه يكشف عندي عن ال analyte حتى لو كان بكمية
+
+188
+00:13:23,640 --> 00:13:27,540
+ضئيلة إذا define sample volume to be applied أول
+
+189
+00:13:27,540 --> 00:13:31,880
+حاجة تحديد حجم ال sample اللي أنا بدي أحطها شغلة
+
+190
+00:13:31,880 --> 00:13:34,860
+تانية variability of sample composition لقيت مش كل
+
+191
+00:13:34,860 --> 00:13:38,770
+العينات لها نفس التركيب مثلاعلى سبيل مثله بقولك
+
+192
+00:13:38,770 --> 00:13:46,550
+الـ pH عشان هيك لازم انا يعني يكون في حاجة تضبط
+
+193
+00:13:46,550 --> 00:13:50,250
+عندى المتغيرات بين العينات يعني على سبيل المثال
+
+194
+00:13:50,250 --> 00:13:55,850
+ممكن انا اعمل pre-treatment لـ Strip بحيث انه يعني
+
+195
+00:13:55,850 --> 00:13:59,330
+يكون في عندى مثلا مثلا زى نظام buffer system يضبط
+
+196
+00:13:59,330 --> 00:14:03,110
+عند الـ pH بحيث انه كل العينات تكون لها نفس
+
+197
+00:14:03,110 --> 00:14:08,710
+الخاصية تمام؟شغل تاني الـ Sample Viscosity قلت في
+
+198
+00:14:08,710 --> 00:14:11,510
+عنده بعض الـ Samples بتكون more viscous than
+
+199
+00:14:11,510 --> 00:14:15,150
+others يعني في عندي عينات هتكون viscous فهيكون
+
+200
+00:14:15,150 --> 00:14:20,530
+مرورها بطيء طب أنا كيف أتجاوز هذه المشكلة بخفف
+
+201
+00:14:20,530 --> 00:14:24,490
+كثافة ال bad material لما أنا أخفف كثافة ال bad
+
+202
+00:14:24,490 --> 00:14:28,110
+material مادة المصنوعة منها ال bad كل ال molecules
+
+203
+00:14:28,110 --> 00:14:31,410
+هتمر بدون معوقات حتى لو كانت ال viscosity إلها
+
+204
+00:14:31,410 --> 00:14:35,540
+عاليةشغلة تانية برضه ممكن تصير Unspecific
+
+205
+00:14:35,540 --> 00:14:38,760
+interaction of your target with a bad material
+
+206
+00:14:38,760 --> 00:14:44,760
+طبعا أنا يعني المادة اللي أنا بدي أدور عليها بدي
+
+207
+00:14:44,760 --> 00:14:48,600
+أمنعها نهائيا أنها ترتبط بال material المصنوعة
+
+208
+00:14:48,600 --> 00:14:51,860
+منها ال bad يعني أنا مابدي أضيف عينة فيها antigen
+
+209
+00:14:51,860 --> 00:14:55,120
+أروح يمسك بال bad وتمشي العينة وتسيبه في هذا
+
+210
+00:14:55,120 --> 00:14:59,490
+المكان أنا بدي هيمشي معهافبالتالي Define Bad
+
+211
+00:14:59,490 --> 00:15:05,730
+Blocking Requirements يعني أمنع أو أشوف المتطلبات
+
+212
+00:15:05,730 --> 00:15:08,790
+اللازمة عشان أني أمنع الـBad هذه أنها تتفاعل أو
+
+213
+00:15:08,790 --> 00:15:11,970
+تحجز أي نوع من الـAntigen اللي أنا بدور عليها
+
+214
+00:15:11,970 --> 00:15:15,470
+Unspecific Interactions of the Target with the
+
+215
+00:15:15,470 --> 00:15:22,350
+Test Line Reagent فلقيت إحنا إذا كنتوا فاكرين في
+
+216
+00:15:22,350 --> 00:15:26,630
+إن الـTest Line Reagent كان عليه Antibodyبدي أخلّي
+
+217
+00:15:26,630 --> 00:15:29,170
+الـ reaction بين الـ antigen و الـ antibody يكوني
+
+218
+00:15:29,170 --> 00:15:33,650
+specific يعني بدي أمنع أي non specific interaction
+
+219
+00:15:33,650 --> 00:15:37,390
+مش أي حاجة تعطيني false positive وتتفاعل مع ال
+
+220
+00:15:37,390 --> 00:15:40,450
+test line وتعطيني long لأ أنا بدي إياه يكون
+
+221
+00:15:40,450 --> 00:15:43,890
+specific بس في حالة وجود ال antigen مرتبط مع ال
+
+222
+00:15:43,890 --> 00:15:48,610
+antibody إنه هذا ال complex بس هو اللي يرتبط مع ال
+
+223
+00:15:48,610 --> 00:15:51,410
+detector antibody اللي موجود على ال test line
+
+224
+00:15:51,410 --> 00:15:57,190
+تمام؟of retention of particles contained in the
+
+225
+00:15:57,190 --> 00:16:01,230
+sample يعني في بعض الأحيان بيبقى في عندي particles
+
+226
+00:16:01,230 --> 00:16:05,250
+في ال sample هذه ال particles أنا بدي أمنعها من
+
+227
+00:16:05,250 --> 00:16:09,050
+المرور كيف يعني؟ في بعض الأحيان أنا بستخدم blood
+
+228
+00:16:09,050 --> 00:16:13,090
+sample عينة blood كاملة يعني مش serum أو مش urine
+
+229
+00:16:13,090 --> 00:16:16,570
+طبعا ال RBCs هذه ال particles مش حتى نظام في ال
+
+230
+00:16:16,570 --> 00:16:20,820
+reactionفأنا بدي أحجزها يعني ما بدي أخليها تمشي مع
+
+231
+00:16:20,820 --> 00:16:25,600
+السائل أنا بدي بس السائل اللي يمشي هذا يعني زي ما
+
+232
+00:16:25,600 --> 00:16:30,220
+أنتوا شايفين الخيوط المكونة للـ Sample Bad قامت
+
+233
+00:16:30,220 --> 00:16:34,320
+بحز الـ RBCs بهذا الشكل يعني بحيث أنه بتروح و هي
+
+234
+00:16:34,320 --> 00:16:39,400
+الـ RBCs لف حوالها و بيضل السائل يمشي لوحده هنا
+
+235
+00:16:39,400 --> 00:16:43,630
+بقولك لو أنت استخدمت Blood Sampleبدي تاخدي بالك من
+
+236
+00:16:43,630 --> 00:16:46,770
+شغلات مهمة أول إشي ال sample volume مش لازم يكون
+
+237
+00:16:46,770 --> 00:16:49,950
+ال sample volume كتير كبير لأنه لو كان ال sample
+
+238
+00:16:49,950 --> 00:16:55,810
+volume كبير ممكن يصير عندك تكسير للخلايا شغلة
+
+239
+00:16:55,810 --> 00:17:00,390
+تانية ال hemolysis لا ينصح بحدوث hemolysis نهائيا
+
+240
+00:17:00,390 --> 00:17:04,070
+لأن يا بنات ال nitrocellulose بعبارة عبارة عن
+
+241
+00:17:04,070 --> 00:17:07,660
+خلفية بيضةعشان أنا أشوف الـ line عليها كويس لازم
+
+242
+00:17:07,660 --> 00:17:10,820
+أضلها بيضة لو صار hemolysis وانتقل لـ free
+
+243
+00:17:10,820 --> 00:17:14,140
+hemoglobin للـ nitrocellulose paper مش هيخليني
+
+244
+00:17:14,140 --> 00:17:17,780
+أميز الخط خاصة لو كان الخط هادة خفيف أو فاتح أو
+
+245
+00:17:17,780 --> 00:17:19,520
+تركيز الـ antigen قليل
+
+246
+00:17:24,530 --> 00:17:27,450
+طيب نيجي للمنطقة التالية الآن إحنا حطينا الـ
+
+247
+00:17:27,450 --> 00:17:31,530
+«Sample» بدها تمشي الـ «Sample» وتروح لـ «Labeled
+
+248
+00:17:31,530 --> 00:17:35,690
+Antibody» أو المكان اللي فيه «Conjugated Antibody»
+
+249
+00:17:35,690 --> 00:17:38,870
+هذا الـ «Antibody» بنعمله «fixation» على
+
+250
+00:17:38,870 --> 00:17:43,210
+«Conjugate Pad» الـ «Conjugate Pad» بتعتبر أصغر
+
+251
+00:17:43,210 --> 00:17:49,630
+مكان على الـ «Lateral Efflot Test» هذه لازم تتحقق
+
+252
+00:17:49,630 --> 00:17:53,840
+فيها مجموعة من الخصائصأول حاجة إنه يكون لها القدرة
+
+253
+00:17:53,840 --> 00:17:59,740
+على إنها تمتص كل الـ Antibody اللي بيضاف إلها كل
+
+254
+00:17:59,740 --> 00:18:03,080
+Detector Conjugate عندها القدرة إنها تمتصه و تثبته
+
+255
+00:18:03,080 --> 00:18:07,080
+في هذا المكان شغل تانية does not interact with the
+
+256
+00:18:07,080 --> 00:18:09,820
+conjugate أنا مابديها تتفاعل مع ال conjugate
+
+257
+00:18:09,820 --> 00:18:13,800
+مابديش يكون فيه أي تفاعلات جانبية maintains the
+
+258
+00:18:13,800 --> 00:18:17,500
+conjugate integrity upon drying طبعا ال strip
+
+259
+00:18:17,500 --> 00:18:21,780
+بتتخذن في ظروف جفاففانا بدي إياها تكون عندها
+
+260
+00:18:21,780 --> 00:18:25,500
+القدرة على إنها تحافظ على الـ Antibody Stable في
+
+261
+00:18:25,500 --> 00:18:28,500
+ظروف الجفاف اللي بده يتم تخزين الـ Kit فيها أو الـ
+
+262
+00:18:28,500 --> 00:18:33,260
+Strip فيها، طبعا؟ Maintains the conjugate in the
+
+263
+00:18:33,260 --> 00:18:37,100
+dry state can easily be more than a year at room
+
+264
+00:18:37,100 --> 00:18:40,720
+temperature يعني هي الآن بدها تحافظ عليه فترة
+
+265
+00:18:40,720 --> 00:18:46,580
+طويلة في ظروف الجفاف ممكن تتجاوز العام طيب، شغل
+
+266
+00:18:46,580 --> 00:18:50,800
+تانية هي ماسكة بالـ conjugateلكن مش متفاعلة معاه
+
+267
+00:18:50,800 --> 00:18:54,440
+بحيث إنه بمجرد ما أحط الـ Sample إن الـ Conjugate
+
+268
+00:18:54,440 --> 00:18:58,820
+هذا المفروض يصير له Release بسرعة وبشكل كامل يعني
+
+269
+00:18:58,820 --> 00:19:02,460
+كل الـ Conjugate ينحل ويمشي مع الـ Sample تمام؟
+
+270
+00:19:02,460 --> 00:19:05,680
+مجرد ما أضيف الـ Sample المفروض الـ Conjugate يصير
+
+271
+00:19:05,680 --> 00:19:11,120
+له Rapid Release Allows for interaction between
+
+272
+00:19:11,120 --> 00:19:14,720
+the detector agent in the conjugate and the target
+
+273
+00:19:14,720 --> 00:19:21,400
+in the sampleطبعاً أنا بدي يعني هذا الـ«ديتكتور»
+
+274
+00:19:21,400 --> 00:19:26,720
+الـ«ديتكتور» الموجود بدي هادد يعني ما تمنعني
+
+275
+00:19:26,720 --> 00:19:29,260
+التفاعل اللي ممكن يصير ما بين الـ«انتجن»
+
+276
+00:19:29,260 --> 00:19:32,940
+والـ«انتبادي» طبعاً ما تكونش هي عائق لحدوث تفاعل
+
+277
+00:19:32,940 --> 00:19:35,320
+بين الـ«انتجن» والـ«انتبادي» لذا هي المفروض
+
+278
+00:19:35,320 --> 00:19:37,820
+تـallow for interaction between the detector
+
+279
+00:19:37,820 --> 00:19:40,920
+agents in the conjugate and the target in the
+
+280
+00:19:40,920 --> 00:19:44,180
+sample وتساعد على حصول هذا التفاعل الـ«انيجن» اللي
+
+281
+00:19:44,180 --> 00:19:47,780
+بعده اللي هو الـanalytical membraneالـ Analytical
+
+282
+00:19:47,780 --> 00:19:50,640
+Membrane هي المساحة هذه اللي بدي أشوف من خلالها
+
+283
+00:19:50,640 --> 00:19:55,580
+شكل ال reaction خط أو خطين هذه لازم تتميز بأنها
+
+284
+00:19:55,580 --> 00:20:00,180
+Large pore size لازم تكون مصنوعة من مادة الـ pores
+
+285
+00:20:00,180 --> 00:20:04,920
+بتاعتها كبيرة بحيث أنه تسمح لأي molecule مهما كان
+
+286
+00:20:04,920 --> 00:20:08,460
+حجمه بالمرور يعني لا تعيق مرور ال molecule بسبب
+
+287
+00:20:08,460 --> 00:20:14,400
+حجمه، تمام؟ شغل تانية، مش بس على قد الحجم، يعني
+
+288
+00:20:14,400 --> 00:20:19,730
+لازمتكون تتميز بخاصية إنه بغض النظر عن الصفات
+
+289
+00:20:19,730 --> 00:20:23,430
+الفيزيائية للـ Sample اللي أنا أضفتها أو للمولكولز
+
+290
+00:20:23,430 --> 00:20:27,390
+اللي بدها تمر تمر بدون معوقات يعني لا تعاني من
+
+291
+00:20:27,390 --> 00:20:30,710
+مشكلة viscosity ولا pH ولا Size ولا حاجة إنها تمر
+
+292
+00:20:30,710 --> 00:20:35,830
+كلها بنفس الجودة وبنفس الكفاءة، تمام؟ شغلة أخيرة
+
+293
+00:20:35,830 --> 00:20:40,670
+عادةً الـNitrocellulose ده بيكون محتوي على Anionic
+
+294
+00:20:40,670 --> 00:20:44,330
+Surfactant إيش الهدف منه؟ إنه يخلي المنطقة
+
+295
+00:20:44,330 --> 00:20:48,610
+Hydrophilicفبالتالي الـ molecules يعني إحنا
+
+296
+00:20:48,610 --> 00:20:51,190
+الأسائل اللي موجود هو ميّه اللي موجود في الـ
+
+297
+00:20:51,190 --> 00:20:54,050
+plasma أو في الـ urine فلازم يكون Hydrophilic عشان
+
+298
+00:20:54,050 --> 00:20:57,450
+الذوب الـ molecules هذه فيه اللي أنا بدي أقيسها و
+
+299
+00:20:57,450 --> 00:21:01,850
+أقدر أخد نتيجة إيش تركيبة الـ nitrocellulose
+
+300
+00:21:01,850 --> 00:21:05,290
+membrane يعني هو دايما بقولك هو not bore not have
+
+301
+00:21:05,290 --> 00:21:08,830
+bore يعني مش عبارة عن ثقوب وإنما عبارة عن شبكة
+
+302
+00:21:08,830 --> 00:21:10,670
+متداخلة بهذه الطريقة
+
+303
+00:21:16,100 --> 00:21:20,200
+نيجي لأخر حاجة اللي هي ال «wake» ال «wake» هي
+
+304
+00:21:20,200 --> 00:21:24,740
+المنطقة اللي في النهاية هذه المطلوب منها أنها تمتص
+
+305
+00:21:24,740 --> 00:21:30,240
+كل الحاجات اللي زادت بعد ال reaction كل السوائل،
+
+306
+00:21:30,240 --> 00:21:34,080
+كل إشي زاد في العينة المفروض يكون عندها القدرة على
+
+307
+00:21:34,080 --> 00:21:37,640
+امتصاصها بحيث أن هذه السوائل ما ترجع باتجاه عكسي
+
+308
+00:21:37,640 --> 00:21:42,930
+وتخرب عنده الفحصIt must prevent the backflow of
+
+309
+00:21:42,930 --> 00:21:45,510
+the liquid into the drying membrane as long as
+
+310
+00:21:45,510 --> 00:21:48,950
+possible» يعني المفروض تمنع الـ زي ما قلنا رجوع
+
+311
+00:21:48,950 --> 00:21:54,670
+السوائل عبر الـ membrane بقدر المستطاع بقولك إحنا
+
+312
+00:21:54,670 --> 00:21:58,850
+بنختارها أو بتختار من مادة مصنوعة من القطن عندها
+
+313
+00:21:58,850 --> 00:22:02,410
+القدرة على إنها تمطس كمية من السائل أكبر من حجم
+
+314
+00:22:02,410 --> 00:22:06,030
+العينة اللي انحتت يعني لو حطينا قدر يعني لو حطت
+
+315
+00:22:06,030 --> 00:22:10,800
+عينةوكمان فوق العينة حجم إضافي لازم يكون عندها
+
+316
+00:22:10,800 --> 00:22:15,720
+القدرة على امتصاصها بحيث إنه مايدلش أي سائل يخرّب
+
+317
+00:22:15,720 --> 00:22:20,020
+عندي نتيجة الفحص بحيث إنه تمتصقه للبقايا فلازم
+
+318
+00:22:20,020 --> 00:22:25,280
+يكون عندها قدرة امتصاص عالية طيب
+
+319
+00:22:25,280 --> 00:22:29,560
+هنا زي عن التلخيص للكلام اللي حكيناه أو إعادة بشكل
+
+320
+00:22:29,560 --> 00:22:34,140
+آخر أو يعني فعليا هنا عملي مع principle هنتمشهم مع
+
+321
+00:22:34,140 --> 00:22:39,330
+بعضأول حاجة الخطوات step number one أول حاجة الـ
+
+322
+00:22:39,330 --> 00:22:44,050
+sample placement أنا بدأ أحط العينة طبعاً إلها
+
+323
+00:22:44,050 --> 00:22:47,590
+مكان محدد بتكون زي فتحة صغيرة أو دائرة في الـ
+
+324
+00:22:47,590 --> 00:22:51,710
+striple plastic بنحط فيها ال sample ال sample بدأ
+
+325
+00:22:51,710 --> 00:22:54,770
+أشوف التعليمات يعني ممكن يقوللي حط sample urine حط
+
+326
+00:22:54,770 --> 00:22:59,210
+serum ممكن serum أو urine ممكن plasma ممكن RBCs
+
+327
+00:22:59,210 --> 00:23:03,330
+holy blood يعنيفممكن يقوللي الـ «سامبل» اعملي لها
+
+328
+00:23:03,330 --> 00:23:05,830
+dilution بالـ «بوفر» بيكون مع ال «kit» dilution
+
+329
+00:23:05,830 --> 00:23:09,790
+بطريقة معينة فأنا بدي أتبع التعليمات بتاعة إضافة
+
+330
+00:23:09,790 --> 00:23:12,810
+الـ «سامبل» و بعدين أحط الـ «سامبل» بتاعتي اللي
+
+331
+00:23:12,810 --> 00:23:15,330
+فيها ال «analytic» اللي أنا عامل بدور عليه الخطوة
+
+332
+00:23:15,330 --> 00:23:20,270
+التانية اللي هي إن الـ «molecules» اللي بدها تساهم
+
+333
+00:23:20,270 --> 00:23:25,150
+في التفاعل هتصير «soluble» تمام؟ كيف بتصير
+
+334
+00:23:25,150 --> 00:23:28,510
+«soluble»؟ عن طريق إضافة الـ «سامبل» الـ «detector
+
+335
+00:23:28,510 --> 00:23:32,630
+molecules» are solubilizedهتصير ذائبة when
+
+336
+00:23:32,630 --> 00:23:35,410
+solubilized the detector molecule mixed with the
+
+337
+00:23:35,410 --> 00:23:39,390
+bind mixed and bind to the analyte in the sample
+
+338
+00:23:39,390 --> 00:23:44,990
+زي ما قولنا طبعا هي العينة أنا أضفتها عندي هنا ال
+
+339
+00:23:44,990 --> 00:23:49,330
+detector molecule مجرد مقضيف العينة هيصير ذائب
+
+340
+00:23:49,330 --> 00:23:53,950
+تعملية الذوبان هذه هتسمحله أنه يتفاعل مع ال
+
+341
+00:23:53,950 --> 00:23:59,140
+analyte اللي أنا بدي أفحصه تمامفهيكون Complex بعد
+
+342
+00:23:59,140 --> 00:24:02,480
+ذلك الخطوة التالتة بعد ما دابت المكونات وصار
+
+343
+00:24:02,480 --> 00:24:05,880
+التفاعل الـ Antigen مع الـ Antibody هتمشي الأشياء
+
+344
+00:24:05,880 --> 00:24:09,600
+اللي اتفاعلت بالخاصية الشعرية لغاية ما توصل لـ
+
+345
+00:24:09,600 --> 00:24:12,900
+Capture Molecule إيش هو Capture Molecule Capture
+
+346
+00:24:12,900 --> 00:24:15,860
+Molecule هو اللي هيعمل Fixation للـ Complement
+
+347
+00:24:15,860 --> 00:24:20,240
+اللي اتكون على الـ Pest line ويعطيني لان Capture
+
+348
+00:24:20,240 --> 00:24:23,040
+Molecule ممكن يكون Antigen أو Antibody حسب أنا
+
+349
+00:24:23,040 --> 00:24:26,600
+اللي إيش بدور عليه يعني أن أنا حسبإذا بدور على
+
+350
+00:24:26,600 --> 00:24:29,720
+Antibody زي الفحص الأولاني عفوا كنت بدور على
+
+351
+00:24:29,720 --> 00:24:32,560
+Antigen في الفحص الأولاني فالـ Capture Molecule
+
+352
+00:24:32,560 --> 00:24:36,080
+إيش كان؟ كان Antibody، تمام؟ هنا أنا بدور على
+
+353
+00:24:36,080 --> 00:24:39,940
+Antibody فالـ Capture Molecule هيكون Antigen،
+
+354
+00:24:39,940 --> 00:24:43,700
+تمام؟ هيكون مثبت على هذا المكان بحيث يعطيني لون
+
+355
+00:24:43,700 --> 00:24:49,040
+لما التفاعل يمشي بعد هيك The control line should
+
+356
+00:24:49,040 --> 00:24:52,720
+always show a visible line otherwise the test is
+
+357
+00:24:52,720 --> 00:24:56,680
+invalid, must be repeatedإذا كانت الاختبار مفيدة،
+
+358
+00:24:56,680 --> 00:24:58,300
+فسيصبح أساساً أساساً أساساً أساساً أساساً أساساً
+
+359
+00:24:58,300 --> 00:25:00,920
+أساساً أساساً أساساً أساساً أساساً أساساً أساساً
+
+360
+00:25:00,920 --> 00:25:05,300
+أساساً أساساً أساساً أساساً أساساً أساساً أساساً
+
+361
+00:25:05,300 --> 00:25:06,620
+أساساً أساساً أساساً أساساً أساساً أساساً أساساً
+
+362
+00:25:06,620 --> 00:25:08,820
+أساساً أساساً أساساً أساساً أساساً أساساً أساساً
+
+363
+00:25:08,820 --> 00:25:23,460
+أساساً أساساً أساساً أساساً أساساً أساساً أساساً
+
+364
+00:25:28,230 --> 00:25:31,830
+Advantages طبعا ممكن أحدد من خلاله Antigen أو
+
+365
+00:25:31,830 --> 00:25:35,950
+Antibody بعدين commercially available easy to
+
+366
+00:25:35,950 --> 00:25:41,290
+perform مافيش instrumentation للقراءة single use
+
+367
+00:25:41,290 --> 00:25:45,970
+rapid test user friendly format سهل جدا معاه
+
+368
+00:25:45,970 --> 00:25:50,330
+الطريقة يعني أي واحد ممكن يقرأها يفهمها very short
+
+369
+00:25:50,330 --> 00:25:54,390
+time to get test result بسرعة يعني بتطلع معايا
+
+370
+00:25:54,390 --> 00:25:58,260
+النتيجةLong-term stability over a wide range of
+
+371
+00:25:58,260 --> 00:26:01,720
+climates يعني بتحمل الظروف الجوية مهما كانت
+
+372
+00:26:01,720 --> 00:26:05,800
+Relatively inexpensive to make يعني سعره وتكلفته
+
+373
+00:26:05,800 --> 00:26:10,300
+مش عالية These
+
+374
+00:26:10,300 --> 00:26:13,640
+advantages زي ما قولنا نتائج qualitative يعني
+
+375
+00:26:13,640 --> 00:26:17,620
+مابيعطيني نتائج رقمية وإنما نتائج qualitative مش
+
+376
+00:26:17,620 --> 00:26:21,260
+quantitative Rapid test can be less sensitive and
+
+377
+00:26:21,260 --> 00:26:24,930
+less accurate عادة ال rapid test هذهيعني بتعتبر
+
+378
+00:26:24,930 --> 00:26:28,670
+Screening Test ومش دايما بتعطيني نتائج دقيقة هي
+
+379
+00:26:28,670 --> 00:26:34,230
+بتكون Less Sensitive and Less Accurate طبعا في
+
+380
+00:26:34,230 --> 00:26:37,590
+عندي أشكال من الـ Lateral Flow ممكن يكون على شكل
+
+381
+00:26:37,590 --> 00:26:42,030
+Strips ممكن يكون على شكل Cassette ممكن يكون على
+
+382
+00:26:42,030 --> 00:26:46,090
+شكل Multi Device ممكن يكون على شكل Midstream زي ما
+
+383
+00:26:46,090 --> 00:26:50,910
+أنتوا شايفين هاي Strip، Midstream، Cassette، Multi
+
+384
+00:26:50,910 --> 00:26:56,170
+Device يعني هذا بياخد أكتر من عينة في نفس الوقتهي
+
+385
+00:26:56,170 --> 00:27:01,530
+أشكال مختلفة للنتيجة طلع معايا عندك مثلا هنا في
+
+386
+00:27:01,530 --> 00:27:06,170
+عينات هذه عينات كلها negative هذه العينات هنا فيها
+
+387
+00:27:06,170 --> 00:27:11,390
+positive result زي ما أنتوا شايفين very fine
+
+388
+00:27:11,390 --> 00:27:16,230
+result
+
+389
+00:27:16,230 --> 00:27:19,650
+عند ال test و هنا حتى فيه برضه خط خفيف كتير
+
+390
+00:27:31,490 --> 00:27:33,930
+Immunochromatographic Strip Inhibition Assay هذا
+
+391
+00:27:33,930 --> 00:27:38,310
+نوع آخر من الـ Immunochromatography صحيح أنا اللي
+
+392
+00:27:38,310 --> 00:27:43,870
+اضطرني أن أحكي إن النتيجة هنا عكسية يعني ضروري جدا
+
+393
+00:27:43,870 --> 00:27:47,090
+أقرأ الـ pamphlet قبل ما أقرأ النتائج وأقرر إذا
+
+394
+00:27:47,090 --> 00:27:49,630
+positive أو negative في هذا النمط من الـ
+
+395
+00:27:49,630 --> 00:27:53,210
+Immunochromatography إذا كانت النتيجة positive
+
+396
+00:27:53,210 --> 00:27:57,380
+بظهر معاكي خط واحدإذا كانت negative حيظهر معاكي
+
+397
+00:27:57,380 --> 00:28:00,600
+خطأ a test is positive when a sample with target
+
+398
+00:28:00,600 --> 00:28:03,400
+analyte is loaded on the sample application bed
+
+399
+00:28:03,400 --> 00:28:06,640
+and flow through the strip to produce a colored
+
+400
+00:28:06,640 --> 00:28:10,520
+line only in the control zone يعني ال positive بس
+
+401
+00:28:10,520 --> 00:28:14,120
+ال control بيعطينا line on the other hand a
+
+402
+00:28:14,120 --> 00:28:17,020
+negative test occurs when the sample with or
+
+403
+00:28:17,020 --> 00:28:19,840
+without target analyte is loaded on the sample
+
+404
+00:28:19,840 --> 00:28:24,120
+application bed and flow throughالـ Strip to
+
+405
+00:28:24,120 --> 00:28:26,960
+produce colored line in both control zone and
+
+406
+00:28:26,960 --> 00:28:29,440
+testing zone يعني في الـ Positive بيعطي خط وفي الـ
+
+407
+00:28:29,440 --> 00:28:32,020
+Negative بيعطي خط يعني طب إيش هي الـ principle
+
+408
+00:28:32,020 --> 00:28:35,280
+بتاعةك؟ طبعا هذا هو الـ Strip اللي إحنا شوفناه قبل
+
+409
+00:28:35,280 --> 00:28:40,840
+بشوية فيه اختلاف بسيط بس الاختلاف هذا أنه عند ال
+
+410
+00:28:40,840 --> 00:28:45,680
+sample line أو ال test line الـ antibody الموجود
+
+411
+00:28:45,680 --> 00:28:53,730
+already مرتبط مع أنتجن تمام؟ الـ antigen هذانفس
+
+412
+00:28:53,730 --> 00:28:57,530
+تركيبة الـ Antigen اللي بالـ Analyte يعني هي الفرق
+
+413
+00:28:57,530 --> 00:29:00,970
+بين الاتنين إحنا في الفحص الأول كان الـ Antibody
+
+414
+00:29:00,970 --> 00:29:04,390
+Free ويجي يرتبط مع الـ Antigen Antibody Complex
+
+415
+00:29:04,390 --> 00:29:08,970
+مظبوط لكن هنا الوضع مختلف طب خليني أنا أشوف إيش
+
+416
+00:29:08,970 --> 00:29:14,410
+اللي بيصير فلقيت إحنا في عندي الـ Analyte وفي عندي
+
+417
+00:29:14,410 --> 00:29:17,550
+الـ Labeled Antibody وفي عندي الـ Test Line الـ
+
+418
+00:29:17,550 --> 00:29:20,600
+Test Line هنا Antibody مرتبط بالـ Antigenوفي عندى
+
+419
+00:29:20,600 --> 00:29:22,680
+الـ secondary antibody اللى احنا متفقين عليه مش
+
+420
+00:29:22,680 --> 00:29:26,600
+عليه خلاف بس الفرق في ال test line طيب فليكى
+
+421
+00:29:26,600 --> 00:29:30,720
+تتخيلى معايا انه في معانا عينة positive positive
+
+422
+00:29:30,720 --> 00:29:33,420
+يعني الـ antigen تبع ال analyte اللى أنا بدور عليه
+
+423
+00:29:33,420 --> 00:29:38,060
+موجود طبيعى هتمشي و هترتبط بالـ detector antibody
+
+424
+00:29:38,060 --> 00:29:43,080
+و بعد هيك هتظلها ماشية طيب السؤال هل الـ detector
+
+425
+00:29:43,080 --> 00:29:46,680
+antibody مع الـ antigen هيقدر يرتبط في هذه الحالة
+
+426
+00:29:46,680 --> 00:29:51,030
+مع ال test lineمش هيقدر يرتبطوا ليش؟ لأن الـ
+
+427
+00:29:51,030 --> 00:29:56,390
+Antibody هنا أساساً مرتبط بـ Antigen فبالتالي الـ
+
+428
+00:29:56,390 --> 00:30:00,530
+Complex هذا كل ياته هيظل ماشي ويعبر عبور الكيران
+
+429
+00:30:00,530 --> 00:30:05,450
+هيرتبط مع مين؟ هيرتبط بس مع الـ Control Line لأن
+
+430
+00:30:05,450 --> 00:30:08,530
+الـ Antibody موجود والـ Antigen موجود هيرتبط بس أو
+
+431
+00:30:08,530 --> 00:30:11,030
+الـ Exist من الـ Antibody هتظل موجودة وترتبط مع
+
+432
+00:30:11,030 --> 00:30:15,050
+الـ Control Line زي ما اتفقنا في النوع العادي طيب
+
+433
+00:30:15,050 --> 00:30:19,220
+لو كان مافيش عندي Analyte مافيش عندي Antigenالـ
+
+434
+00:30:19,220 --> 00:30:22,820
+Antibody هذا هيظل Free يعني مش هيكون مرتبط بالـ
+
+435
+00:30:22,820 --> 00:30:27,820
+Antigen بالتالي، هيمشي لغاية ما يوصل الـ Test Line
+
+436
+00:30:27,820 --> 00:30:31,620
+الـ Antibody هنا بديهي لأنه مش مرتبط بالـ Antigen
+
+437
+00:30:31,620 --> 00:30:36,280
+هيرتبط بالـ Antigen الموجود مثبت على الـ Antibody
+
+438
+00:30:36,280 --> 00:30:40,500
+في الـ Test Line و هيظهر عندي لون عند الـ Test
+
+439
+00:30:40,500 --> 00:30:44,550
+Line وقت إيش ظهر اللونلما كان الـ Antibody free
+
+440
+00:30:44,550 --> 00:30:47,570
+أمتى كان الـ Antibody free؟ لما كانت العينة
+
+441
+00:30:47,570 --> 00:30:51,210
+negative إذاً هيك العينة لما بتكون negative بطلع
+
+442
+00:30:51,210 --> 00:30:55,930
+معايا two line لما بتكون positive بطلع معايا one
+
+443
+00:30:55,930 --> 00:31:01,390
+line اللي هو تاع الـ control solution containing
+
+444
+00:31:01,390 --> 00:31:04,470
+target analyte is applied on the sample
+
+445
+00:31:04,470 --> 00:31:08,830
+application bed and prefix labeled antibody gets
+
+446
+00:31:08,830 --> 00:31:11,490
+hydrated and start flowing with moving liquid
+
+447
+00:31:11,490 --> 00:31:14,540
+لغاية الآن مش اختلافةTest line contain pre
+
+448
+00:31:14,540 --> 00:31:17,620
+-immobilized antigen same analyte to be detected
+
+449
+00:31:17,620 --> 00:31:20,000
+بنحط عليه الـ antigen اللي هو نفس الـ analyte اللي
+
+450
+00:31:20,000 --> 00:31:23,160
+أنا بدي أقيسه which binds specifically to label
+
+451
+00:31:23,160 --> 00:31:26,220
+conjugate هذا المفروض بيرتبط مع الـ label
+
+452
+00:31:26,220 --> 00:31:28,920
+conjugate اللي هو الـ antibody اللي labelled
+
+453
+00:31:28,920 --> 00:31:32,300
+Control line contains pre-immobilized secondary
+
+454
+00:31:32,300 --> 00:31:35,610
+antibodyعنده القدرة على إنه يرتبط مع الـ Labelled
+
+455
+00:31:35,610 --> 00:31:37,990
+Conjugate أو مع الـ Labelled Antibody هذا إحنا
+
+456
+00:31:37,990 --> 00:31:41,550
+متفقين عليه يعني الإختلاف بس في النقطة الوسطانية
+
+457
+00:31:41,550 --> 00:31:45,270
+اللي هي الخط بتاع الـ Test بيكون مرتبط مع الـ
+
+458
+00:31:45,270 --> 00:31:51,250
+Antibody، الـ Antigen لأن
+
+459
+00:31:51,250 --> 00:31:55,870
+when liquid sample reaches at the test line pre
+
+460
+00:31:55,870 --> 00:31:58,650
+-immobilized antigen will bind to the labelled
+
+461
+00:31:58,650 --> 00:32:02,410
+conjugate in caseTarget analyzed in sample
+
+462
+00:32:02,410 --> 00:32:06,190
+solution is absent يعني أمتى هيرتبط الـ Conjugated
+
+463
+00:32:06,190 --> 00:32:10,690
+antibody لو كان الـ Antigen مش موجود or present in
+
+464
+00:32:10,690 --> 00:32:13,830
+such low quantity that some sites of label
+
+465
+00:32:13,830 --> 00:32:17,130
+antibody conjugate were vacant يعني أو كان موجود
+
+466
+00:32:17,130 --> 00:32:20,970
+بكميات قليلة والـ Conjugated antibody لازالت
+
+467
+00:32:20,970 --> 00:32:24,190
+الأماكن اللي فيه شاغرة و بالإمكان أنه يرتبط يعني
+
+468
+00:32:24,190 --> 00:32:28,250
+بظهر عندى اللون لو كان التركيز كتير خفيف أو كان
+
+469
+00:32:28,250 --> 00:32:32,000
+مافيش عندى أصلا Antigen خالص«الأنتجين في المحلول
+
+470
+00:32:32,000 --> 00:32:36,780
+المثالي» و«الشخص اللذي قام بعمل محاولة في تجارة
+
+471
+00:32:36,780 --> 00:32:40,560
+قمبيت للتعامل مع مجموعات تسمى Conjugate» «الشخص
+
+472
+00:32:40,560 --> 00:32:43,500
+اللذي قام بعمل محاولة للتعامل مع مجموعات تسمى
+
+473
+00:32:43,500 --> 00:32:44,100
+Conjugate» «الشخص اللذي قام بعمل محاولة للتعامل مع
+
+474
+00:32:44,100 --> 00:32:45,780
+مجموعات تسمى Conjugate» «الشخص اللذي قام بعمل
+
+475
+00:32:45,780 --> 00:32:48,620
+محاولة للتعامل مع مجموعات تسمى Conjugate» «الشخص
+
+476
+00:32:48,620 --> 00:32:52,180
+اللذي قام بعمل محاولة للتعامل مع مجموعات تسمى
+
+477
+00:32:52,180 --> 00:32:52,760
+Conjugate» «الشخص اللذي قام بعمل محاولة
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/puJoH0Q5i1w_postprocess.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/puJoH0Q5i1w_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..eb6bdffa46104d6957768c3e1f867f681f8f0c94
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/puJoH0Q5i1w_postprocess.srt
@@ -0,0 +1,2156 @@
+1
+00:00:01,160 --> 00:00:06,160
+بسم الله الرحمن الرحيم إن شاء الله رب العالمين راح
+
+2
+00:00:06,160 --> 00:00:10,040
+نكون معاكم في مساق علم المناعة والأمثال العملي
+
+3
+00:00:10,040 --> 00:00:17,260
+وراح ناخد اليوم أول موضوع من موضوعاتنا حناخد فكرة
+
+4
+00:00:17,260 --> 00:00:21,960
+بسيطة يعني كمقدمة عن الـ Antigen و الـ Antibody و
+
+5
+00:00:21,960 --> 00:00:25,440
+الـ Antigen Antibody Reactions عشان نوصل لأول
+
+6
+00:00:25,440 --> 00:00:31,050
+مجموعة من الفحوصاتبنيجي لنوع تاني اللي هو الـ
+
+7
+00:00:31,050 --> 00:00:34,990
+Agglutination Inhibition هذا شبيه بالـ
+
+8
+00:00:34,990 --> 00:00:38,010
+Hemagglutination Inhibition بتاع الفيروس والـ RBCs
+
+9
+00:00:38,010 --> 00:00:43,990
+اللي حكينا عنه قبل بشوية هنا الـ متفاعل يعني الـ
+
+10
+00:00:43,990 --> 00:00:47,850
+ال kit ايش بيكون فيه ال kit بيكون فيه Antibody و
+
+11
+00:00:47,850 --> 00:00:52,810
+Antigen محمل على Latex Particles تمام؟ هدول الأصل
+
+12
+00:00:52,810 --> 00:00:55,790
+أنا لو ضفتهم على بعض يعملوا reaction ويعطوني
+
+13
+00:00:55,790 --> 00:01:01,380
+agglutination خلو؟طيب، هلاقيت أنا لو ضفت عينة أنا
+
+14
+00:01:01,380 --> 00:01:05,900
+شاكة أنه يكون فيها Antigen إيش هيصير؟ هيصير الـ
+
+15
+00:01:05,900 --> 00:01:10,480
+Antigen هذا يتنافس على الـ Antibody هو و الـ
+
+16
+00:01:10,480 --> 00:01:16,220
+Antigen اللي على letex particles تمام؟ الأصل الـ
+
+17
+00:01:16,220 --> 00:01:19,100
+Antibody هذا بدون Antigen الـ Antibody يتفاعل مع
+
+18
+00:01:19,100 --> 00:01:21,060
+ال particles اللي عليها الـ Antigen يعطيني
+
+19
+00:01:21,060 --> 00:01:24,720
+أجلوتينيشن لكن لو أنا جبت عينة و العينة هذه كان
+
+20
+00:01:24,720 --> 00:01:28,650
+الـ Antigen موجود فيهاهيروح اش يعمل الـ Antigen
+
+21
+00:01:28,650 --> 00:01:32,270
+يتنافس مع الـ Particles اللي عليها الـ Antigen
+
+22
+00:01:32,270 --> 00:01:36,010
+ويروح و هو مرتبط بالـ Antibody طبعا الـ Antibody
+
+23
+00:01:36,010 --> 00:01:40,190
+كميته محدودة فهيصير Neutralization له، هيصير
+
+24
+00:01:40,190 --> 00:01:44,790
+استهلاك للـ Antibody، تمام؟ فلأ لما بيصير استهلاك
+
+25
+00:01:44,790 --> 00:01:48,350
+للـ Antibody هتظل الـ Latex Particles مش لاقيا
+
+26
+00:01:48,350 --> 00:01:52,550
+Antibody تتفاعل معاه وبالتالي هتظلها Free و
+
+27
+00:01:52,550 --> 00:01:56,550
+هتعطيني Negative Reactionnegative reaction يعني
+
+28
+00:01:56,550 --> 00:02:01,370
+positive test negative reaction إيش يعني؟ negative
+
+29
+00:02:01,370 --> 00:02:05,590
+reaction معنى الكلام إن العينة فيها antigen أخدت
+
+30
+00:02:05,590 --> 00:02:08,950
+الـ antibody ومنعته إنه يتفاعل مع الـ latex
+
+31
+00:02:08,950 --> 00:02:12,510
+particles عشان هيك الـ latex particles ما اتفاعلت
+
+32
+00:02:12,510 --> 00:02:16,470
+وقططني negative ال positive reaction معنى الكلام
+
+33
+00:02:16,470 --> 00:02:22,210
+إنه مافيش عندي antigen في العينة وبالتالي ماصارش
+
+34
+00:02:22,210 --> 00:02:26,070
+عنديكمبتيشن ماصارش منافسة على الـ Antibody
+
+35
+00:02:26,070 --> 00:02:29,270
+وبالتالي الـ Antibody قدر يشتغل بكل أرياحية
+
+36
+00:02:29,270 --> 00:02:34,750
+ويعطيني positive reaction تمام؟ في هنا مثال عليها،
+
+37
+00:02:34,750 --> 00:02:39,990
+إيه هذا شرحه؟ طيب في هذا المثال زي ما قلنا اللي هو
+
+38
+00:02:39,990 --> 00:02:46,030
+مثال فحص الحمل قديما طبعا في الحمل احنا بندور على
+
+39
+00:02:46,030 --> 00:02:50,030
+هرمون الـ HCG بندور على هرمون الـ HCG إذا كان
+
+40
+00:02:50,030 --> 00:02:53,080
+موجود في الـ Serumأو في الـ urine معنى الكلام أنه
+
+41
+00:02:53,080 --> 00:02:57,740
+فيه pregnancy هذا الهرمون بتطلع من الـ placenta
+
+42
+00:02:57,740 --> 00:03:02,520
+بتاعة الجملة طيب ماشي خلينا نشوف كيف فكرة الفحص
+
+43
+00:03:02,520 --> 00:03:06,340
+أنه في عندنا particles Heptankarian conjugate يعني
+
+44
+00:03:06,340 --> 00:03:10,320
+افترض انها particles محمل عليها الهرمون هذا ال kit
+
+45
+00:03:10,320 --> 00:03:14,560
+يعني هذا لسه المتفائلات أنا ماضفتش العينة ومعاه
+
+46
+00:03:14,560 --> 00:03:18,620
+كمان ال antibody ال antibody لمن؟ لل HCG ال
+
+47
+00:03:18,620 --> 00:03:23,220
+antibody لهذه ال moleculesهلاقيت الأصل لما أضيف
+
+48
+00:03:23,220 --> 00:03:27,680
+الـ Particles مع الـ Antibody يصير Agglutination
+
+49
+00:03:27,680 --> 00:03:32,520
+تمام؟ لكن لو كان الهرمون موجود يعني الست حامل يعني
+
+50
+00:03:32,520 --> 00:03:36,820
+عندها الهرمون تاع الحمل إيش هيصير؟ هييجي هرمون
+
+51
+00:03:36,820 --> 00:03:42,480
+الحمل ينافس الـ Particle المحمل عليها الـ Antigen
+
+52
+00:03:42,480 --> 00:03:44,840
+ينافس الـ Antigen هذا المحمل على الـ Particles
+
+53
+00:03:44,840 --> 00:03:48,620
+وهيروح الـ Antibody يرتبط بهرمون الحمل الموجود في
+
+54
+00:03:48,620 --> 00:03:53,130
+الـ Urineوبالتالي هيظل هذا free مش هيلاقي antibody
+
+55
+00:03:53,130 --> 00:03:58,490
+يرتبط فيه فبالتالي مش هيعطيني clumping فبالتالي
+
+56
+00:03:58,490 --> 00:04:02,030
+النتيجة negative agglutination معنى الكلام
+
+57
+00:04:02,030 --> 00:04:09,610
+positive pregnancy test هنا
+
+58
+00:04:09,610 --> 00:04:14,350
+الفكرة الفحث اسمه conglutination أو
+
+59
+00:04:14,350 --> 00:04:19,110
+coagglutination ايش الفكرة فيه؟الفكرة فيه أن أنا
+
+60
+00:04:19,110 --> 00:04:23,610
+بجيب staff avarius ميتة الـ Staff avarius هذه
+
+61
+00:04:23,610 --> 00:04:29,970
+عليها routine A الـ routine A له القدرة على إنه
+
+62
+00:04:29,970 --> 00:04:36,990
+يرتبط بالـ FC portion للـ antibody فإيش بروح بعمل؟
+
+63
+00:04:36,990 --> 00:04:39,830
+بجيب الـ antibody بحمله على الـ Staff avarius يعني
+
+64
+00:04:39,830 --> 00:04:42,810
+بدل ما حمله على particles بحمله على الـ Staff
+
+65
+00:04:42,810 --> 00:04:47,350
+avarius برتبط مع الـ FC portion للـ Staff avarius
+
+66
+00:04:48,440 --> 00:04:51,840
+وبالتالي الـ Fab region اللي بدى تم من خلالها
+
+67
+00:04:51,840 --> 00:04:56,200
+التفاعل بتضل Exposed، مارتبطت فبالتالي كانت هنا
+
+68
+00:04:56,200 --> 00:05:00,120
+البكتيريا هذه كـ Carrier للـ Antibody ومبعد هيك
+
+69
+00:05:00,120 --> 00:05:03,180
+بجيب العينة اللي عندى العينة فيها Antigen طبعا
+
+70
+00:05:03,180 --> 00:05:07,780
+بدور على أي نوع من أنواع الـ Antigenات اللي أنا
+
+71
+00:05:07,780 --> 00:05:10,540
+حملتله Antibody على هذه البكتيريا يعني هنا
+
+72
+00:05:10,540 --> 00:05:12,680
+البكتيريا مالهاش دعوة في الـ Reaction بكتيريا بس
+
+73
+00:05:12,680 --> 00:05:15,750
+كـ Carrier Moleculeوبجيب الـ Antigen سواء في Body
+
+74
+00:05:15,750 --> 00:05:21,290
+Fluids أو في أي حاجة وباجي بفعلها مع الـ Antibody
+
+75
+00:05:21,290 --> 00:05:24,510
+المحمل عليه Staph Aureus والاصل طبعا إذا كانت
+
+76
+00:05:24,510 --> 00:05:27,830
+النتيجة Positive أو الـ Antigen موجود هيعطيني
+
+77
+00:05:27,830 --> 00:05:32,130
+Agglutination نيجي
+
+78
+00:05:32,130 --> 00:05:35,410
+للـ Antiglobulin mediated agglutination برضه هذا
+
+79
+00:05:35,410 --> 00:05:41,080
+يعني مهم أنه ناخد فكرة عنهلأنه من أنواع الـ
+
+80
+00:05:41,080 --> 00:05:43,520
+agglutination اللي هو الـ Antiglobulin-mediated
+
+81
+00:05:43,520 --> 00:05:49,920
+agglutination إيش هذا؟ فاكرين لما حكينا في مراحل
+
+82
+00:05:49,920 --> 00:05:55,080
+الـ agglutination في مرحلة sensitization ومرحلة
+
+83
+00:05:55,080 --> 00:05:58,600
+agglutination مرحلة sensitization ومرحلة lattice
+
+84
+00:05:58,600 --> 00:06:02,680
+formation صح؟ وحكينا كمان إنه مش كل الـ antibodies
+
+85
+00:06:02,680 --> 00:06:06,480
+عندها القدرة على إنها توصل لمرحلة الـ
+
+86
+00:06:06,480 --> 00:06:09,700
+agglutination الـ visible agglutinationوقلنا لما
+
+87
+00:06:09,700 --> 00:06:14,640
+بتوصل بسميها Incomplete Antibodies Incomplete
+
+88
+00:06:14,640 --> 00:06:19,480
+لأنها بتحتاج لمساعدة عشان توصل لمرحلة الـ Visible
+
+89
+00:06:19,480 --> 00:06:27,540
+Agglutination وتعمل الـ Lattice طيب مثال عليها فحص
+
+90
+00:06:27,540 --> 00:06:31,100
+الـ Coombs Test ممكن سمعتوا فيه Antiglobulin أو
+
+91
+00:06:31,100 --> 00:06:37,610
+Coombs Test هذا الفحص بكشف من خلاله علىإذا كان في
+
+92
+00:06:37,610 --> 00:06:42,690
+عندى RBCs sensitized بالـ Antibody يعني في عندنا
+
+93
+00:06:42,690 --> 00:06:47,030
+Antibody أجى أتفاعل مع الـ RBCs لكن ماقدر يعطيني
+
+94
+00:06:47,030 --> 00:06:51,110
+visible agglutination فأنا بدى أساعد خلايا هذه الـ
+
+95
+00:06:51,110 --> 00:06:54,570
+sensitized أنها توصل لمرحلة الـ agglutination هي
+
+96
+00:06:54,570 --> 00:06:59,370
+incomplete بدها مساعدة فبضيف عامل مساعد عشان
+
+97
+00:06:59,370 --> 00:07:02,710
+يعطيني الـ visible agglutination إيش هو العامل
+
+98
+00:07:02,710 --> 00:07:07,870
+المساعدهذا اسمه Anti-Globulin Reagent Anti
+
+99
+00:07:07,870 --> 00:07:10,210
+-Globulin Reagent إيش هو الـ Anti-Globulin
+
+100
+00:07:10,210 --> 00:07:16,790
+Reagent؟ هو عبارة عن Anti-Antibody تمام؟ Anti
+
+101
+00:07:16,790 --> 00:07:21,430
+-Antibody برتبط مع الـ FC بورشن للـ Antibody فإيش
+
+102
+00:07:21,430 --> 00:07:25,270
+اللي هيصير؟ هي عندنا الـ Reaction خلايا متفاعلة
+
+103
+00:07:25,270 --> 00:07:29,450
+بصير لها sensitization بس مش صير أجلوتناشنفبيجي
+
+104
+00:07:29,450 --> 00:07:33,890
+الـ Anti-Human Globulin اللي هو Anti IGG قلناه
+
+105
+00:07:33,890 --> 00:07:37,410
+برتبط الـ FC portion لهذا الـ Antibody مع الـ FC
+
+106
+00:07:37,410 --> 00:07:40,810
+portion لهذا شبكهم مع بعض بيجي لهدول التانية
+
+107
+00:07:40,810 --> 00:07:45,990
+بشبكهم مع بعض و هكذا فبيوصل الخلايا لمرحلة الـ
+
+108
+00:07:45,990 --> 00:07:49,860
+Visible Agglutinationسمناها Antiglobulin Test لأنه
+
+109
+00:07:49,860 --> 00:07:53,260
+بيعتمد على الـ Agent اسمه Antiglobulin أو
+
+110
+00:07:53,260 --> 00:07:56,340
+Antihuman Globulin لأن الـ Antiglobulin اللي أنا
+
+111
+00:07:56,340 --> 00:08:01,060
+بجيبه لازم يكون Antihuman مخصص للـ Antibodies دا
+
+112
+00:08:01,060 --> 00:08:03,740
+الـ Human عشان يعطيني Reaction
+
+113
+00:08:07,380 --> 00:08:11,400
+طيب، هنا في عندي بعض الـ instruments لقراية الـ
+
+114
+00:08:11,400 --> 00:08:16,100
+agglutination في عندي أو تقنية اسمها Particle
+
+115
+00:08:16,100 --> 00:08:18,560
+Enhanced Therapeutometric Inhibition Assay
+
+116
+00:08:18,560 --> 00:08:22,660
+Particle Counting Immunoassay هلأ هناخدهم كل واحدة
+
+117
+00:08:22,660 --> 00:08:29,620
+لحال و نفهم إيش الـ principle بتاعتنا هذه
+
+118
+00:08:29,620 --> 00:08:33,080
+التقنية لقياس الـ agglutination طبعا الـ
+
+119
+00:08:33,080 --> 00:08:36,940
+agglutination لما بيصير هيعمل عندي large particles
+
+120
+00:08:37,540 --> 00:08:40,260
+والـ Large particles هذه هتعمل turbidity في
+
+121
+00:08:40,260 --> 00:08:44,540
+المحلول هذا اشي مفروغ منه اشي بديهي طبعا ال
+
+122
+00:08:44,540 --> 00:08:47,040
+turbidity لو احنا مررنا فيها ضوء هتعمل light
+
+123
+00:08:47,040 --> 00:08:51,140
+scattering ال aggregates هذه ويتأثر على ال
+
+124
+00:08:51,140 --> 00:08:55,220
+absorbance لها الضوء الفكرة عندنا بتتمت بتشبه اللي
+
+125
+00:08:55,220 --> 00:08:57,460
+قلناها توي اللي هو ال agglutination inhibition
+
+126
+00:08:57,460 --> 00:09:01,460
+أساسي وهذه على فكرة بيستخدموها للكشف عن ال drugs
+
+127
+00:09:01,460 --> 00:09:06,980
+عن بعض الأدوية و عن المخدرات في جسم بعض المرضىكيف
+
+128
+00:09:06,980 --> 00:09:11,120
+التقنية هذه بتشتغل؟ خلوا بالكم الآن بيجيبوا Latex
+
+129
+00:09:11,120 --> 00:09:14,440
+particles محمّل عليها الـ Drug وفي عندنا Free
+
+130
+00:09:14,440 --> 00:09:19,820
+Antibody تمام؟ في الوضع الطبيعي إذا ماكانش فيه أي
+
+131
+00:09:19,820 --> 00:09:23,700
+حاجة تتدخل في التفاعل هيصير Reaction ويصير
+
+132
+00:09:23,700 --> 00:09:27,520
+Agglutination طبعا طالما صار Agglutination يعني
+
+133
+00:09:27,520 --> 00:09:30,620
+زادت الـ Turbidity زادت الـ Turbidity زاد الـ
+
+134
+00:09:30,620 --> 00:09:34,760
+Absorbance تمام؟ خلصنا من الجهة هذه طيب تخيلوا أنه
+
+135
+00:09:34,760 --> 00:09:39,010
+موجود Drugفي الدم أو في الـ Plasma إذا موجود Drug
+
+136
+00:09:39,010 --> 00:09:43,470
+في الـ Plasma هيروح يعمل الـ Neutralization للـ
+
+137
+00:09:43,470 --> 00:09:46,670
+Antibody يعني بدل ما الـ Antibody اللي المفروض
+
+138
+00:09:46,670 --> 00:09:50,390
+يرتبط مع الـ Particles هيرتبط إشي منه مع الـ
+
+139
+00:09:50,390 --> 00:09:53,370
+Particles و هيصير .. يعني هيعمل الـ Drug هذا
+
+140
+00:09:53,370 --> 00:09:56,470
+منافسة على الـ Antibody فبالتالي الـ Antibody
+
+141
+00:09:56,470 --> 00:09:59,190
+هيصير له Neutralization يعني بدل ما يرتبط بالـ
+
+142
+00:09:59,190 --> 00:10:03,090
+Particles هذههيرتبط بالـ Drug فهتظل الـ particles
+
+143
+00:10:03,090 --> 00:10:07,030
+free فهو لما ضلت free الـ turbidity هتكون قليلة و
+
+144
+00:10:07,030 --> 00:10:09,750
+الـ absorbance هيكون قليل يعني كل ما قلل
+
+145
+00:10:09,750 --> 00:10:14,710
+absorbance كل ما كان الـ Drug معدله أعلى في العينة
+
+146
+00:10:14,710 --> 00:10:17,650
+هنا هذا الكلام هو اللي شرحناه بس نشوف هنا
+
+147
+00:10:17,650 --> 00:10:21,310
+Therefore the rate of increase of absorbance hence
+
+148
+00:10:21,310 --> 00:10:25,930
+the rate of the increase in turbidity is inversely
+
+149
+00:10:25,930 --> 00:10:28,470
+proportional of the concentration of the drug
+
+150
+00:10:28,760 --> 00:10:32,840
+يتناسب عكسيا مع تركيز لـ Drug كل ما زاد الـ Drug
+
+151
+00:10:32,840 --> 00:10:36,480
+كل ما كان الـ Competition أعلى وكل ما ارتبط مع الـ
+
+152
+00:10:36,480 --> 00:10:39,220
+Antibody وضلت ال particles free فبالتالي الـ
+
+153
+00:10:39,220 --> 00:10:44,340
+Absorbance هيكون تبعها أقل هذه شريحة أخرى توضح
+
+154
+00:10:44,340 --> 00:10:49,160
+برضه البتنة تقنية البتنة بتشوفوا كيف يعني لما
+
+155
+00:10:49,160 --> 00:10:54,580
+بيكون ال drug مش موجود بتكون ال particles متماسكة
+
+156
+00:10:54,580 --> 00:10:56,680
+مع بعض فبالتالي التربيدية بتبقى عالية و ال
+
+157
+00:10:56,680 --> 00:10:59,980
+absorbance بيكونبيكون الـ Light Scattering عالي
+
+158
+00:10:59,980 --> 00:11:03,560
+طبعا الـ Absorbence بيكون عالي هنا لما تبقى ال
+
+159
+00:11:03,560 --> 00:11:06,440
+particles متباعدة لما يبقى ال drug مش موجود تبقى
+
+160
+00:11:06,440 --> 00:11:08,960
+ال particles متباعدة فبالتالي مافيش Scattering
+
+161
+00:11:08,960 --> 00:11:13,820
+كتير بتبقى تربيت نيجي لتقنية تانية برضه لقياس ال
+
+162
+00:11:13,820 --> 00:11:21,080
+agglutination التقنية هذه بتعتمد على قياس الـ non
+
+163
+00:11:21,080 --> 00:11:25,680
+-agglutinated particles كيف يعني؟يعني في الـ Latex
+
+164
+00:11:25,680 --> 00:11:29,540
+particles محملة بالـ Antibody بضيف عليها الـ
+
+165
+00:11:29,540 --> 00:11:33,540
+Antigen لأن لما يضعف عليها الـ Antigen هتعمل
+
+166
+00:11:33,540 --> 00:11:38,280
+Agglutination الـ Agglutination هذه حجمها كبير
+
+167
+00:11:38,280 --> 00:11:45,420
+يعني بتستثنى الفكرة بتعتمد على إنه في عنا جهاز بعد
+
+168
+00:11:45,420 --> 00:11:49,080
+ال particles الصغيرة اللي ما عملت Agglutination
+
+169
+00:11:49,080 --> 00:11:54,230
+فبيجي الـ Antibodyالـ Antigen الـ Antigen الموجود
+
+170
+00:11:54,230 --> 00:11:57,430
+في العينة بتفاعل مع الـ Antibody المحمل على Latex
+
+171
+00:11:57,430 --> 00:12:01,410
+particles وبيعمل Large Aggregates هياخد جزء من ال
+
+172
+00:12:01,410 --> 00:12:05,510
+particles هذه لأنها كبرت ومش راح تنعدى هيظل كمية
+
+173
+00:12:05,510 --> 00:12:09,390
+من ال particles هي اللي هتقرأ في الجهاز طبعا هذه
+
+174
+00:12:09,390 --> 00:12:12,810
+هيكون تناسبها عكسي لأن كل ما زادت كمية ال
+
+175
+00:12:12,810 --> 00:12:18,330
+antibodiesكل ما اتفعلت أكتر مع الـ Particles وعملت
+
+176
+00:12:18,330 --> 00:12:22,350
+أجلوتينيات أكتر واللي ضلت الكمية للقراءة كمية
+
+177
+00:12:22,350 --> 00:12:28,150
+قليلة فبالتالي هذه بيكون تناسبها عكسي مع التركيز
+
+178
+00:12:28,150 --> 00:12:37,710
+الـ Antigen في العينة بيشبه جهاز السلكة أو هذا طيب
+
+179
+00:12:37,710 --> 00:12:41,590
+الـ Agglutination Test عادة يعني احنا ممكن ناخدها
+
+180
+00:12:41,590 --> 00:12:45,250
+qualitative أو semi quantitativeالنتيجة تاعتها
+
+181
+00:12:45,250 --> 00:12:48,670
+qualitative يعني positive أو negative عشان هيك
+
+182
+00:12:48,670 --> 00:12:51,570
+بنات بنعتبر بشكل عام هي screening test يعني
+
+183
+00:12:51,570 --> 00:12:55,950
+نتائجها مش كتير دقيقة a glutination test can be
+
+184
+00:12:55,950 --> 00:12:58,770
+used in a qualitative manner to assess for the
+
+185
+00:12:58,770 --> 00:13:01,630
+presence of antigen or not or antibody يعني هل
+
+186
+00:13:01,630 --> 00:13:05,070
+موجود أو مش موجود الانتجن أو الانتيبادي الانتيبادي
+
+187
+00:13:05,070 --> 00:13:08,510
+is mixed with the particulate antigenand a
+
+188
+00:13:08,510 --> 00:13:11,470
+positive test is indicated by the agglutination of
+
+189
+00:13:11,470 --> 00:13:14,110
+the particulate antigen خلاص يعني إذا شوفت ال
+
+190
+00:13:14,110 --> 00:13:16,390
+agglutination أو شوفت ال positive reaction عادة
+
+191
+00:13:16,390 --> 00:13:20,670
+النتيجة
+
+192
+00:13:20,670 --> 00:13:24,350
+تعيتها بتكون equalitative لكن أنا ممكن أعملها
+
+193
+00:13:24,350 --> 00:13:29,070
+quantitative or semi quantitative كيف ممكن أعملها
+
+194
+00:13:29,070 --> 00:13:31,870
+quantitative يعني أنا في النهاية بدأ أشوف positive
+
+195
+00:13:31,870 --> 00:13:37,390
+أو negative شوفواالان انا لو فى عندى عينة مثلا
+
+196
+00:13:37,390 --> 00:13:41,910
+عينة serum فىها antibody وبدى اشوف الـtiter لل
+
+197
+00:13:41,910 --> 00:13:47,050
+antibody هذا او تركيز ال antibody هذا كيف بعمل؟
+
+198
+00:13:47,050 --> 00:13:51,270
+بعمل طبعا فى عندنا لهذا الغرض اما اذا انا بدى
+
+199
+00:13:51,270 --> 00:13:55,070
+استخدم volumes كبيرة ممكن استخدم قنابيب عادية او
+
+200
+00:13:55,070 --> 00:13:58,870
+انى بستخدم ال micro-titer blades يعني هو blades زى
+
+201
+00:13:58,870 --> 00:14:02,270
+ما انتوا شايفين فى wheels صغيرة ممكن استخدمها
+
+202
+00:14:02,270 --> 00:14:06,700
+العمل هذه التخفيفاتبعمل من الـ Antibody بتاعي
+
+203
+00:14:06,700 --> 00:14:10,740
+Serial Dilution من العينة وباجي باخد من الـ
+
+204
+00:14:10,740 --> 00:14:14,480
+Antigen نفس الكمية على كل الـ Dilution اللي أنا
+
+205
+00:14:14,480 --> 00:14:17,620
+عملته عدنا هشوفها في الصورة اللي بعد هتكون أضحى
+
+206
+00:14:17,620 --> 00:14:25,420
+بعد هيك بشوف وين آخر واحدة أعطتني Positive آخر
+
+207
+00:14:25,420 --> 00:14:29,600
+واحدة أعطتني Positive بتعبر عن أعلى تخفيف قدر
+
+208
+00:14:29,600 --> 00:14:33,380
+يعطيني Positive اللي هو الـ Titer للـ Antibody أنا
+
+209
+00:14:33,380 --> 00:14:37,120
+بسميهThe maximum dilution that gives visible
+
+210
+00:14:37,120 --> 00:14:44,500
+agglutination is called retiter طبعا هذا الكلام
+
+211
+00:14:44,500 --> 00:14:48,200
+يعني ممكن نطبقه زي ما قلتلكم أحيانا إحنا بنطبقه في
+
+212
+00:14:48,200 --> 00:14:50,900
+ال tube عادية وممكن في ال micro-titer blades وممكن
+
+213
+00:14:50,900 --> 00:14:53,620
+على ال slide العادية يعني عندنا لقدام شوية في
+
+214
+00:14:53,620 --> 00:14:57,620
+العملية استيلولوجيا هنعمل تخفيفاتها دي على slide
+
+215
+00:14:57,620 --> 00:15:02,340
+هاي هنا صورة موضحة يعني خلينا نفترض عند الأنبوبة
+
+216
+00:15:02,340 --> 00:15:09,140
+رقم 1خدوا بالكم هذه نتائج heme agglutination test
+
+217
+00:15:09,140 --> 00:15:11,440
+فاكرينه بتاع الفيروس أنه الفيروس بيعمل
+
+218
+00:15:11,440 --> 00:15:17,300
+agglutination للـ RBCs شكل الـ agglutination بيكون
+
+219
+00:15:17,300 --> 00:15:22,740
+كانتشار للخلايا على قاع البلات ليس لأنه بتعمل زي
+
+220
+00:15:22,740 --> 00:15:27,760
+شبكة رقيقة هك و بتنتشر على سطح البلات بينما الـ
+
+221
+00:15:27,760 --> 00:15:30,820
+negative بتلاقي الخلايا ما اتفعلت ماعملتش
+
+222
+00:15:30,820 --> 00:15:36,080
+agglutination فبتتجمع على شكلنقطة في قاع البلات
+
+223
+00:15:36,080 --> 00:15:39,940
+نفسه إذا كان البلات على شكل U شاب يعني البلات ممكن
+
+224
+00:15:39,940 --> 00:15:43,680
+تكون على شكل U شاب زي حرف الـU أو حرف الـV من تحت
+
+225
+00:15:43,680 --> 00:15:48,920
+فلما بتيجي الخلايا تترسب في تحت في تجويف لتيوب
+
+226
+00:15:48,920 --> 00:15:52,540
+الصغيرة هذه هتعطيني شكل drop هذي في حالة
+
+227
+00:15:52,540 --> 00:15:55,740
+الـnegative وفي حالة الـpositive هتعطيني هذا الشكل
+
+228
+00:15:55,740 --> 00:16:02,640
+هنا عملنا serial dilution مثلا نص ربع ثمنبتهيألي
+
+229
+00:16:02,640 --> 00:16:05,260
+هذا الشغل انتوا شغلتهو موضوع الـ Dilution شغلتهو
+
+230
+00:16:05,260 --> 00:16:10,420
+في النزف و قعدنا هنحكي كيف بنعمله كمان مرة طبعا
+
+231
+00:16:10,420 --> 00:16:14,420
+يعني باخد كمية محددة من الـ Antibody و بضيف عليها
+
+232
+00:16:14,420 --> 00:16:17,340
+كمية محددة من السيرام في النهاية بتصير عندى
+
+233
+00:16:17,340 --> 00:16:21,280
+التخفيفات هذه واحد ل .. واحد لاثنين واحد لاربعة
+
+234
+00:16:21,280 --> 00:16:26,710
+واحد لتمانية واحد لستعش and so on باجي باخدكمية
+
+235
+00:16:26,710 --> 00:16:29,830
+محددة من الـ RBCs اللي أنا بعتبرها الـ Antigen هنا
+
+236
+00:16:29,830 --> 00:16:33,230
+أو أي Antigen أنا بتشتغل عليه و بحطه على كل
+
+237
+00:16:33,230 --> 00:16:36,610
+الأنابيب هذه بالتساوي و بعمللها إذا بدها
+
+238
+00:16:36,610 --> 00:16:39,690
+Incubation بعمللها Incubation حسب الفترة المطلوبة
+
+239
+00:16:39,690 --> 00:16:43,310
+بعد هيك بتطلع عشان أشوف ال positive result لو جينا
+
+240
+00:16:43,310 --> 00:16:49,010
+للأنبوبة للعينة رقم 1 العينة رقم 1 عند أنبوبة 1
+
+241
+00:16:49,010 --> 00:16:54,820
+إلى 64 آخر أنبوبة كان فيها positiveهذه العينة بقول
+
+242
+00:16:54,820 --> 00:16:59,220
+أن الـ Titer بتاعها 64 تركيز الـ Antibody فيها
+
+243
+00:16:59,220 --> 00:17:04,320
+دلوا شغال معايا عند 64 طيب الأنبوبة اللي بعدها الـ
+
+244
+00:17:04,320 --> 00:17:08,460
+Titer تمانية طب مين أعلى الـ 64 أعلى لأنه أنا
+
+245
+00:17:08,460 --> 00:17:11,800
+استمرت في التخفيف وهو استمر يعطيني positive معناه
+
+246
+00:17:11,800 --> 00:17:14,680
+الكلام أن الـ Titer أعلى أو كمية الـ Antibody
+
+247
+00:17:14,680 --> 00:17:20,900
+الموجودة في العينة أعلى العينة هذه 512 العينة هذه
+
+248
+00:17:21,200 --> 00:17:24,940
+مافيش Zero يعني الـ Titer تبعها أقل من 2 أقل من
+
+249
+00:17:24,940 --> 00:17:27,100
+الأنبوبة دي لأنه كله Negative العينة أصلا Negative
+
+250
+00:17:27,100 --> 00:17:31,480
+يعني أنا العينة اللي بتكون أصلا معايا Negative
+
+251
+00:17:31,480 --> 00:17:34,420
+تخلوا بالكم العينة اللي بتكون معايا Negative
+
+252
+00:17:34,420 --> 00:17:37,640
+المفروض ماعملليهااش Titer يعني لأنه أنا بعمل الـ
+
+253
+00:17:37,640 --> 00:17:43,040
+Titer بعد ما تطلع العينة Positive عشان أشوف كمية
+
+254
+00:17:43,040 --> 00:17:49,060
+أو الـ Titer بتاع ال Antibodyطيب العينة هذه
+
+255
+00:17:49,060 --> 00:17:54,820
+الـTiter 32 العينة هذه 32 العينة هذه 4 اتطلعوا
+
+256
+00:17:54,820 --> 00:17:57,600
+معايا على العينة هذه شوية غريبة أو شكل ال reaction
+
+257
+00:17:57,600 --> 00:18:01,680
+فيها غريب في البداية كانت تعطيني negative بعدين
+
+258
+00:18:01,680 --> 00:18:05,820
+أعطت positive بعدين رجعت تعطي negative إيش تفسيرنا
+
+259
+00:18:05,820 --> 00:18:09,100
+لهيك عينة؟ يعني أنا أول إشي كانت تعطي negative لكن
+
+260
+00:18:09,100 --> 00:18:14,070
+لما خففتها أعطت positiveإذا فاكرين لما حكينا إن
+
+261
+00:18:14,070 --> 00:18:18,170
+كمية الـ Antigen إلى الـ Antibody Ratio مهمة جداً
+
+262
+00:18:18,170 --> 00:18:22,710
+يعني أنا لازم أخد كمية متكافئة من الـ Antigen و
+
+263
+00:18:22,710 --> 00:18:26,390
+الـ Antibody لما بعمل reaction لو كانت الكمية هذه
+
+264
+00:18:26,390 --> 00:18:30,190
+غير متكافئة سواء بزيادة الـ Antigen أو بزيادة الـ
+
+265
+00:18:30,190 --> 00:18:34,330
+Antibody هتعمل عندي False Negative فهذه العينة
+
+266
+00:18:34,330 --> 00:18:39,730
+عادة بيكون فيها تركيز عالي للـ Antibodyمقدر يعني
+
+267
+00:18:39,730 --> 00:18:42,850
+لأنه التركيز عالي أو كمية الـ Antibody عالية
+
+268
+00:18:42,850 --> 00:18:46,870
+أعطتني False Negative وبعد هيك لما خففت بلشت تعطي
+
+269
+00:18:46,870 --> 00:18:49,730
+Positive ووصلت للـ Optimal Concentration للـ
+
+270
+00:18:49,730 --> 00:18:53,950
+Concentration المناسب لإنه يصير Agglutination وبعد
+
+271
+00:18:53,950 --> 00:18:57,210
+هيك خلص الـ Agglutination عند 128 إذن الـ Titer
+
+272
+00:18:57,210 --> 00:19:02,930
+128 فهذه الظاهرة عندنا هنشوفها بنسميها Prozone
+
+273
+00:19:02,930 --> 00:19:06,800
+PhenomenaProson Phenomena بيبقى فيها تركيب الـ
+
+274
+00:19:06,800 --> 00:19:11,880
+Antibody عالي تركيز الـ Antibody عالي وبالتالي في
+
+275
+00:19:11,880 --> 00:19:15,720
+أول تيوبات مابتعطينيش positive لكن مع التخفيف
+
+276
+00:19:15,720 --> 00:19:21,240
+بتبلش تعطيني الـ positive طيب
+
+277
+00:19:21,240 --> 00:19:25,060
+نيجي لتعريف الـ TiterTiter is the quantity of a
+
+278
+00:19:25,060 --> 00:19:29,700
+substance required to produce a reaction with a
+
+279
+00:19:29,700 --> 00:19:34,600
+given volume of another substanceيعني كمية المادة
+
+280
+00:19:34,600 --> 00:19:39,160
+المطلوبة عشان تعطيني reaction مع كمية محددة من
+
+281
+00:19:39,160 --> 00:19:45,620
+المادة الأخرى إذا أنا عملت تخفيف للـ Antibody بدي
+
+282
+00:19:45,620 --> 00:19:49,260
+أشوف أنه هو أعلى تخفيف قادر يعطيني reaction هو الـ
+
+283
+00:19:49,260 --> 00:19:52,840
+Titer Antibody Titer، وعن هنا حكينا بشكل عام عن
+
+284
+00:19:52,840 --> 00:19:55,360
+الـ Titer هنا الـ Antibody Titer the highest
+
+285
+00:19:55,360 --> 00:19:59,760
+dilution of the biological sampleطبعاً عادةً بتكون
+
+286
+00:19:59,760 --> 00:20:02,820
+Serum أو أي عينة أنا بشتغل عليها Antibody that
+
+287
+00:20:02,820 --> 00:20:05,560
+still result in agglutination اللي هتفضل تعطيني
+
+288
+00:20:05,560 --> 00:20:08,940
+agglutination with no agglutination being observed
+
+289
+00:20:08,940 --> 00:20:12,360
+at any higher dilution يعني آخر واحدة هتعطيني
+
+290
+00:20:12,360 --> 00:20:15,560
+dilution بعد هيك نهائيًا مش هيبين أي agglutination
+
+291
+00:20:15,560 --> 00:20:19,900
+لو أنا زودت التخفيف فهذا بعتبره الـTiter The term
+
+292
+00:20:19,900 --> 00:20:23,300
+is used in surgical reactions and is determined by
+
+293
+00:20:23,300 --> 00:20:26,190
+preparing serial dilution تعلم نقولنا كيفof
+
+294
+00:20:26,190 --> 00:20:29,850
+antibody to which a constant amount of antigen is
+
+295
+00:20:29,850 --> 00:20:36,110
+added هذه طريقة عمل الـ Titrate الجدول
+
+296
+00:20:36,110 --> 00:20:40,770
+هذا بيوضح اندي شغلة مهمة هاي ان انا انا ملاحظين
+
+297
+00:20:40,770 --> 00:20:43,710
+انا عملت dilution واحد لعشرة لعشرين لاربعين
+
+298
+00:20:43,710 --> 00:20:50,370
+لتمانين أنصار للاخر الوضع الطبيعي انه لو انا جبت
+
+299
+00:20:50,370 --> 00:20:54,730
+عينة زي هك العينة هذه هتبدأ تعطيني positive
+
+300
+00:20:55,330 --> 00:20:58,710
+Positive بعد هيك يعني حسب الـTiter تبعها هتصير
+
+301
+00:20:58,710 --> 00:21:04,690
+تعطي Negative صح؟ أنا جبت التخفيفات هذه وحطيت
+
+302
+00:21:04,690 --> 00:21:08,390
+عليهم نفس الكمية من الـAntigen وبدأ أشوف النتيجة
+
+303
+00:21:08,390 --> 00:21:13,990
+المتوقعة زي ما قلتلكم النتيجة المتوقعة أنه يبدأ ال
+
+304
+00:21:13,990 --> 00:21:21,370
+reaction strong ويبدأ يضعف لكن في عندي موضوع تركيز
+
+305
+00:21:21,370 --> 00:21:25,450
+الـAntigen وAntibody هذا كتير مهمخلّينا نفهم
+
+306
+00:21:25,450 --> 00:21:29,470
+النقطة هذه فلقيت يا بنات زي ما قلتلكم في البداية
+
+307
+00:21:29,470 --> 00:21:34,170
+أنه لازم يكون في تكافؤ بين كمية الـ Antigen و الـ
+
+308
+00:21:34,170 --> 00:21:38,050
+Antibody بحيث أن يعطوني Positive Reaction يعني إذا
+
+309
+00:21:38,050 --> 00:21:40,470
+كان في تكافؤ بين كمية الـ Antigen و الـ Antibody
+
+310
+00:21:40,470 --> 00:21:44,150
+مافي مشكلة و هيعطوني Positive Reaction بهذا الشكل
+
+311
+00:21:44,150 --> 00:21:47,650
+المنطقة اللي فيها تكافؤ بسميها الـ Equivalence
+
+312
+00:21:47,650 --> 00:21:52,990
+Zone لكن لو كان تركيز الـ Antibody عالي كتيرزي ما
+
+313
+00:21:52,990 --> 00:21:55,730
+قلتلكم لو كان تركيز الـ Antibody عالي طبعا هذه
+
+314
+00:21:55,730 --> 00:21:58,870
+هنشرح إيش اللي بيصير بالظبط لو كان تركيز الـ
+
+315
+00:21:58,870 --> 00:22:01,970
+Antibody عالي هتلاقي إنه في البداية راح يبدأ
+
+316
+00:22:01,970 --> 00:22:06,290
+يعطيكي Negative ومع التخفيف هيبلش يعطي Positive
+
+317
+00:22:06,290 --> 00:22:10,150
+يوصل لأعلى درجة من الـPositivity في الـEquivalence
+
+318
+00:22:10,150 --> 00:22:15,490
+Zone بعد هيك هيبلش برضه يخف الـPositive لغاية ما
+
+319
+00:22:15,490 --> 00:22:19,870
+يوصللحاجة بنسميها الـ Bossed Zone الـ Bossed Zone
+
+320
+00:22:19,870 --> 00:22:22,550
+هي المنطقة اللي بيبقى فيها تركيز الـ Antigen أعلى
+
+321
+00:22:22,550 --> 00:22:27,850
+من الـ Antibody فما بتعطيناش فما بتعطيناش positive
+
+322
+00:22:27,850 --> 00:22:33,210
+تقطينا negative هلقيت كل Antibody يعني كل سيرم أو
+
+323
+00:22:33,210 --> 00:22:38,390
+كل عينة أو كل Antibody ال equivalence zone هتكون
+
+324
+00:22:38,390 --> 00:22:41,590
+مختلفة حسب تركيزهم وحسب الـTiter اللي في النهاية
+
+325
+00:22:41,590 --> 00:22:45,550
+هيطلع تمام؟ يعنيهي أنه بـ Antibodies في البداية
+
+326
+00:22:45,550 --> 00:22:48,790
+هتعطيك positive لأن التنقر بتاعها متكافئ يعني إحنا
+
+327
+00:22:48,790 --> 00:22:51,570
+دخلين في ال equivalence zone من البداية وبعدين
+
+328
+00:22:51,570 --> 00:22:53,990
+بتعطيك negative لأ في antibodies تانية لأ حيبقى
+
+329
+00:22:53,990 --> 00:22:56,830
+تركيزها عالي جدا لدرجة إنه مش هتعطي negative
+
+330
+00:22:56,830 --> 00:23:00,290
+positive إلا إذا اتخففت فحسب تركيز ال antibody في
+
+331
+00:23:00,290 --> 00:23:07,290
+العينة بتظهر معايا النتيجة نيشيل ال advantages and
+
+332
+00:23:07,290 --> 00:23:11,350
+disadvantages of coagulation reaction أول حاجة ال
+
+333
+00:23:11,350 --> 00:23:15,170
+advantagesأول حاجة أن الفحوصات ما بتكلف كتير يعني
+
+334
+00:23:15,170 --> 00:23:19,650
+تكلفتها بسيطة ممكن أحصل على semi-quantitative
+
+335
+00:23:19,650 --> 00:23:22,230
+result زي ما شوفنا توي عملنا titration وأخدنا
+
+336
+00:23:22,230 --> 00:23:27,110
+titer شغل تاني مهم أنها فحوصات سريعة يعني مابحتاج
+
+337
+00:23:27,110 --> 00:23:30,370
+وقت طويل عشان أنجزها يعني خلال دقائق تكون أخدت
+
+338
+00:23:30,370 --> 00:23:35,810
+النتيجة طيب، هل احتجت أي أجهزة لقراءة النتيجة الـ
+
+339
+00:23:35,810 --> 00:23:39,940
+agglutinationلأ ما بحتاج يعني بالعين المجردة ممكن
+
+340
+00:23:39,940 --> 00:23:45,620
+أخد النتيجة تبعتي ما بحتاج أجهزة متقدمة شغلة تانية
+
+341
+00:23:45,620 --> 00:23:49,040
+أي إن كان نوع الـ Antigen اللي أنا بستخدمه سواء ان
+
+342
+00:23:49,040 --> 00:23:51,960
+الـ Antigen جاي من بكتيريا طبيعية أو من كائن طبيعي
+
+343
+00:23:51,960 --> 00:23:57,060
+أو من RBC أو محملة على Latex Particles ما بحتاج
+
+344
+00:23:57,060 --> 00:24:00,300
+Microscope لأقرأ الـ Agglutination يعني ممكن قراقة
+
+345
+00:24:00,300 --> 00:24:03,890
+الـ Agglutination بالعين المجردةIncreased degree
+
+346
+00:24:03,890 --> 00:24:06,890
+of sensitivity يعني إلها درجة عالية من الـ
+
+347
+00:24:06,890 --> 00:24:11,050
+sensitivity هذه الفحوصات Great variety of
+
+348
+00:24:11,050 --> 00:24:13,970
+detectable substances يعني هنلاقي عنا مجموعة كتير
+
+349
+00:24:13,970 --> 00:24:16,970
+كبيرة من الـ substances اللي ممكن نحددها عن طريق
+
+350
+00:24:16,970 --> 00:24:20,690
+فحوصات أو نبحث عنها أو نكشف عن وجودها من خلال الـ
+
+351
+00:24:20,690 --> 00:24:25,090
+agglutination reactionsIf the sample contain
+
+352
+00:24:25,090 --> 00:24:27,990
+microorganism هذه النقطة مهمة يعني لو العينة أنا
+
+353
+00:24:27,990 --> 00:24:31,510
+بدور فيها على microorganisms لاشترط إن الـ
+
+354
+00:24:31,510 --> 00:24:35,390
+microorganisms هذه تبقى viable لأنه لو بدي أعمل
+
+355
+00:24:35,390 --> 00:24:39,110
+مزرعة مثلا ال organism هذه لازم تكون viable لكن
+
+356
+00:24:39,110 --> 00:24:42,770
+طالما أنا بدور على أنتجن الانتجن موجود سواء
+
+357
+00:24:42,770 --> 00:24:46,450
+البكتيريا كانت طيبة أو حتى لو ماتت بعد فترة إجهت
+
+358
+00:24:46,450 --> 00:24:46,890
+الانتجن
+
+359
+00:24:51,950 --> 00:24:55,210
+الـ Disadvantages بتاعتها مهمة كتير بدنا نتذكر
+
+360
+00:24:55,210 --> 00:24:59,310
+دايما إنها تعتبر Screening tests only and negative
+
+361
+00:24:59,310 --> 00:25:02,110
+result doesn't rule out the disease يعني لو طلعت
+
+362
+00:25:02,110 --> 00:25:05,670
+اندي نتيجة negative لا تستثني المرض The quantity
+
+363
+00:25:05,670 --> 00:25:08,970
+of antigen of antibody may be below the
+
+364
+00:25:08,970 --> 00:25:12,810
+sensitivity of the kidيعني ممكن يبقى فيه Antibody
+
+365
+00:25:12,810 --> 00:25:17,590
+أو Antigen لكن الـ kit هذا يعني ال sensitivity
+
+366
+00:25:17,590 --> 00:25:20,190
+بتاعة ال kit هذه ماعندها القدرة إنها اتقسم
+
+367
+00:25:20,190 --> 00:25:23,770
+فبالتالي بتظل Screening Test ممكن تعطيني False
+
+368
+00:25:23,770 --> 00:25:28,670
+Positive أو False Negative Results False Positive
+
+369
+00:25:28,670 --> 00:25:33,670
+Results من إيش ممكن تيجي؟ هلاقيت لو أنا عملت الفحص
+
+370
+00:25:33,670 --> 00:25:37,470
+في تيوب أنا بشوف ال agglutination يعني هو الفحص
+
+371
+00:25:37,470 --> 00:25:39,990
+الفحصات هذه بتاعة ال agglutination ممكن تنعمل في
+
+372
+00:25:39,990 --> 00:25:44,400
+تيوبوممكن تنعمل على slide فإذا أنا عملتها في tube
+
+373
+00:25:44,400 --> 00:25:49,720
+إذا أنا عملتها في tube بحتاج centrifuge الآن لو
+
+374
+00:25:49,720 --> 00:25:54,900
+أنا عملت centrifuge زيادة over centrifugation زيد
+
+375
+00:25:54,900 --> 00:26:00,520
+عن حده فهذا هيؤدي لتجمع كبير من الخلايا تجمع شديد
+
+376
+00:26:00,520 --> 00:26:04,830
+للخلايا في قاع الأنبوبالتجمع هذا لما آجي أحرك أنا
+
+377
+00:26:04,830 --> 00:26:07,450
+كيف بعرف إنه فيه agglutination لأ بطلع إيبانات من
+
+378
+00:26:07,450 --> 00:26:10,370
+الـ centrifuge وبعمل dislodgement ماشي عن
+
+379
+00:26:10,370 --> 00:26:14,890
+dislodgement بضرب ضربة خفيفة على قعلة يوم الآن إذا
+
+380
+00:26:14,890 --> 00:26:18,590
+ده بالراسب هذا معنى الكلام إنه فيش agglutination
+
+381
+00:26:18,590 --> 00:26:24,510
+لكن إذا طلع قطع متماسقة مع بعض معنى الكلام إنه فيه
+
+382
+00:26:24,510 --> 00:26:28,030
+agglutination فبالتالي لو أنا إجيت عملت centrifuge
+
+383
+00:26:28,030 --> 00:26:31,480
+بالزيادة هذا هيقدّي لتماسك ال particlesوهيعطيني
+
+384
+00:26:31,480 --> 00:26:35,940
+false positive result containment equipment ممكن
+
+385
+00:26:35,940 --> 00:26:40,340
+تعطيني زي لو كانت ملوثة ب dust ب dirt ب
+
+386
+00:26:40,340 --> 00:26:43,980
+fingerprint اللي هي بصمات الأصابع and so on auto
+
+387
+00:26:43,980 --> 00:26:49,960
+agglutination او ذاتي في بعض الخلايا ممكن يصير لها
+
+388
+00:26:49,960 --> 00:26:54,420
+clumping بدون ما اضيف لها antibodyفي بعض الخلايا
+
+389
+00:26:54,420 --> 00:26:57,780
+ممكن يصير لها autoagglutination يعني لحالها تتخثر
+
+390
+00:26:57,780 --> 00:27:04,440
+نتيجة وجود مشاكل طبعا يعني خاصة مثلا خلايا الدم في
+
+391
+00:27:04,440 --> 00:27:07,380
+بعض الأحيان ممكن يصير لها تخثر بدون إضافة أي
+
+392
+00:27:07,380 --> 00:27:10,580
+antibody إذا كان موجود لها autoantibody في السيرام
+
+393
+00:27:10,580 --> 00:27:13,840
+أو في البلازم اللي أنا بشتغل عليه delay in reading
+
+394
+00:27:13,840 --> 00:27:18,000
+testing ممكن يعمل drying للانتجن ويبين كأنه
+
+395
+00:27:18,000 --> 00:27:21,650
+agglutination saline stored in glass bottlesممكن
+
+396
+00:27:21,650 --> 00:27:23,770
+الـ Colloidal Silica هذه بتعطيكي False Positive
+
+397
+00:27:23,770 --> 00:27:26,130
+Result اللي موجودة في الـ Glass Bottle Using
+
+398
+00:27:26,130 --> 00:27:29,650
+Plasma Instead of Serum بتعطيكي False Positive
+
+399
+00:27:29,650 --> 00:27:32,590
+أكيد هذه مجربة لأن الـ Fibrinogen هيعطيني False
+
+400
+00:27:32,590 --> 00:27:37,130
+Positive مع أشياء كتير Hemolized أو Lybemic Sample
+
+401
+00:27:37,130 --> 00:27:40,550
+شغلة برضه مهمة اللي هي الموضوع الـ Cross Reactions
+
+402
+00:27:40,550 --> 00:27:43,770
+أحياناً كتير الـ Antibody مايكونش كتير specific
+
+403
+00:27:43,770 --> 00:27:47,190
+فممكن يعمل reaction مع أكتر من نوع من الـ Antigens
+
+404
+00:27:47,190 --> 00:27:52,740
+الـ False Negativeأول حاجة Under centrifugation
+
+405
+00:27:52,740 --> 00:27:56,280
+أنا ماعملت centrifuge بالشكل الكافي الشغل التاني
+
+406
+00:27:56,280 --> 00:27:59,600
+ال reagent خربان Inactive reagent Incorrect
+
+407
+00:27:59,600 --> 00:28:02,320
+incubation time لو أنا محتاجة incubation time أنا
+
+408
+00:28:02,320 --> 00:28:05,800
+ماعطيت ال incubation time الكافي Insufficient
+
+409
+00:28:05,800 --> 00:28:08,860
+incubation time proson phenomena اللي حكينا عنها
+
+410
+00:28:08,860 --> 00:28:13,060
+قويإنه يبقى تركيز الـ Antibody عالي جدًا لدرجة إنه
+
+411
+00:28:13,060 --> 00:28:16,080
+يعطيني False Negative إحنا هناخد تفسيرها لقدام إن
+
+412
+00:28:16,080 --> 00:28:19,020
+شاء الله لكن أعرفه إنه لو كان الـ Antibody عالي
+
+413
+00:28:19,020 --> 00:28:21,720
+كتير أو الـ Antigen عالي كتير هيعطيني False
+
+414
+00:28:21,720 --> 00:28:26,240
+Negative delay in testing procedure تأخير في إجراء
+
+415
+00:28:26,240 --> 00:28:32,900
+الفحص لو أنا أتأخرت في إجراء الفحص هنلاحظ إنه ممكن
+
+416
+00:28:32,900 --> 00:28:38,110
+الـ Antibodies تنفك عن الـ Antigenالان نيجي
+
+417
+00:28:38,110 --> 00:28:40,970
+للتجربة الأولى اللى احنا بدنا نشتغلها هناخد إيش
+
+418
+00:28:40,970 --> 00:28:44,070
+فكرة التجربة هي تطبيق بسيط جدا على ال
+
+419
+00:28:44,070 --> 00:28:47,990
+agglutination ويعني هنعمله في تيوب عشان نشوف ال
+
+420
+00:28:47,990 --> 00:28:52,050
+agglutination بشكل واضح بإذن الله إيش هنعمل؟ طبعا
+
+421
+00:28:52,050 --> 00:28:55,730
+إحنا عارفين يا بنات في فصائل الدم إنه لو كان شخص
+
+422
+00:28:55,730 --> 00:28:59,310
+عنده فصيلة معينة هلاقي في ال serum بتاعه ال
+
+423
+00:28:59,310 --> 00:29:03,330
+antibody المضاد لهذه الفصيلة يعني إذا كان فصيلته A
+
+424
+00:29:03,330 --> 00:29:11,230
+هلاقي عنده antibody في ال serum، صح؟طبعا الان بدنا
+
+425
+00:29:11,230 --> 00:29:16,250
+نفترض ان انا مطلوب مني احدد التايتر للـ Anti-B عند
+
+426
+00:29:16,250 --> 00:29:20,750
+شخص معين فاصيلته A يعني هو فاصيلته A وعنده Anti-B
+
+427
+00:29:20,750 --> 00:29:23,150
+في الـ Serum فبده احدد التايتر تلقى الـ Anti-B
+
+428
+00:29:23,150 --> 00:29:27,870
+بدنا نشوف كيف بدنا نحدده منطقيا هنعمل Serial
+
+429
+00:29:27,870 --> 00:29:31,490
+Dilution من الـ Serum ونضيف عليها كمية محددة من
+
+430
+00:29:31,490 --> 00:29:31,590
+الـ
+
+431
+00:29:36,190 --> 00:29:40,630
+بالزمن باي بيتز بالزمن red cells with the antigen
+
+432
+00:29:40,630 --> 00:29:43,810
+to be tested كيف يعني؟ يعني أنا مثلا بدي أفحص
+
+433
+00:29:43,810 --> 00:29:46,930
+الـtiter بتاع الـAnti-B بالزمن بيه cells اللي
+
+434
+00:29:46,930 --> 00:29:50,710
+عليها الـB-antigen بالزمن الـTested Serum اللي بدي
+
+435
+00:29:50,710 --> 00:29:57,490
+أعمل عليه Alpha كيف الشغل؟ الآن نيجي أول حاجة في
+
+436
+00:29:57,490 --> 00:30:00,250
+التجربة بتاعتنا بدنا نحضر Serial Dilution من
+
+437
+00:30:00,250 --> 00:30:03,850
+الـSerum هلاقيت الـSerum باخد منه 500 microliter
+
+438
+00:30:03,850 --> 00:30:07,400
+على أول أنبوبةايها دي مش هعمل فيها dilution ولا
+
+439
+00:30:07,400 --> 00:30:11,500
+حاجة زي ما هي هيكون تركيزها 1 إلى 2 لأنه أنا هضيف
+
+440
+00:30:11,500 --> 00:30:15,520
+عليها 500 من ال cells فهيصير 500 إلى 1000 يعني 1
+
+441
+00:30:15,520 --> 00:30:18,840
+إلى 2 نيجي لل tube اللي بعدها لل tube اللي بعدها
+
+442
+00:30:18,840 --> 00:30:23,160
+هنعمللها تخفيف 500 من ال serum إلى 500 من ال
+
+443
+00:30:23,160 --> 00:30:27,540
+saline فهيصير تخفيفها 1 إلى 4 فلاقيتها دي هاخد
+
+444
+00:30:27,540 --> 00:30:31,060
+منها 500 على الأنبوبة اللي بعدها أخد ال 500 هذه
+
+445
+00:30:31,060 --> 00:30:35,830
+أحط عليهم 500 salineبتصير 1 إلى 8 من هذه بعمل mix
+
+446
+00:30:35,830 --> 00:30:39,990
+و 500 عن اللي بعدها أخدتها ده في النزف عملته الـ
+
+447
+00:30:39,990 --> 00:30:44,370
+Serial Dilution أنا بتذكر يعني لغاية وانكرر
+
+448
+00:30:44,370 --> 00:30:48,110
+العملية هذه لآخر الأنابيب هلاقيت آخر أنبوبة هيكون
+
+449
+00:30:48,110 --> 00:30:53,330
+فيها 500 من الأنبوبة اللي قابلها مع 500 Saline
+
+450
+00:30:53,330 --> 00:30:58,150
+هيصير الـ Total فيها 1000 مابينفع بشيل منهم 500 و
+
+451
+00:30:58,150 --> 00:31:03,780
+بكبهم أو بحطهم في أنبوبة تانية احتياطإذن أنا حضرت
+
+452
+00:31:03,780 --> 00:31:08,780
+الـ Serial Dilution 1 لـ 2، 1 لـ 4، 8، 1 لـ 16، 1
+
+453
+00:31:08,780 --> 00:31:14,520
+لـ 32، للآخر وكل أنبوب قداش كان فيه 500 كل تيوب
+
+454
+00:31:14,520 --> 00:31:20,460
+كان فيه 500 ميكروليتر باخد بعد هيك 500 ميكروليتر
+
+455
+00:31:20,460 --> 00:31:25,140
+blood RBCs معمولة لها suspension بطريقة معينة
+
+456
+00:31:25,140 --> 00:31:28,080
+عليها الـ Antigen للـ Antibody اللي بتعمله الـ
+
+457
+00:31:28,080 --> 00:31:31,890
+Titration هنا في السيرموبعمل الـ Home بضيف على كل
+
+458
+00:31:31,890 --> 00:31:34,930
+الخلايا نفس الـ على الكل الأنابيب نفس الكمية من
+
+459
+00:31:34,930 --> 00:31:40,950
+الخلايا وبعمل 6 Fuge وبشوف أني أمبوبة اللي أعطتني
+
+460
+00:31:40,950 --> 00:31:44,250
+positive يعني لو كانت مثلا آخر أمبوبة اللي أعطتني
+
+461
+00:31:44,250 --> 00:31:48,570
+positive 16 1 إلى 16 معنى الكلام الـ Titer 1 على
+
+462
+00:31:48,570 --> 00:31:53,550
+16 لو كانت مثلا 8 بقول الـ Titer .. مش مولت 1 إلى
+
+463
+00:31:53,550 --> 00:31:57,930
+16 لأ الـ Titer 16 التركيز 1 إلى 16 الـ Titer 16لو
+
+464
+00:31:57,930 --> 00:32:01,690
+كانت 1 لـ 8 التركيز اللي أعطاني آخر positive بيكون
+
+465
+00:32:01,690 --> 00:32:08,010
+الـ tighter ash 8 طيب هنا في شغلة مهمة في المناعة
+
+466
+00:32:08,010 --> 00:32:10,670
+بعرفش يعني انتوا يمكن عندكم فكرة عنها بس أنا بأكد
+
+467
+00:32:10,670 --> 00:32:15,710
+عليها لإنها بتلزمنا كتير في معاملنا اللي هي تحضير
+
+468
+00:32:15,710 --> 00:32:19,910
+الـ CSD ماهو الـ dilution؟ dilution عبارة عن
+
+469
+00:32:19,910 --> 00:32:23,690
+decreasing the concentration of a solution يعني
+
+470
+00:32:23,690 --> 00:32:28,570
+أنه أنا بخفف، بقلل تركيز ال solutionعن طريق أنه
+
+471
+00:32:28,570 --> 00:32:32,010
+أنا بعد ما أخفف أضرب في factor أعرف الـ factor
+
+472
+00:32:32,010 --> 00:32:35,830
+اللي أنا أخففته وفي النهاية أنا بضرب فيه بالإضافة
+
+473
+00:32:35,830 --> 00:32:38,930
+لإن Pollution بلزمنا في تحضير التخفيفات بلزمنا في
+
+474
+00:32:38,930 --> 00:32:41,290
+تحضير العينات في تحضير الـ buffer في تحضير
+
+475
+00:32:41,290 --> 00:32:44,710
+الـcontrolات مش بس في المناعة في كل مكان في
+
+476
+00:32:44,710 --> 00:32:47,450
+المناعة بلزمنا في تحضير الـ titer للـ antibodies
+
+477
+00:32:47,450 --> 00:32:53,250
+عادة قلتلكم العينات اللي بتطلع عندي positive
+
+478
+00:32:53,250 --> 00:32:56,010
+بعمللها titration عشان أعرف قدش تركيز الـ antibody
+
+479
+00:32:57,120 --> 00:33:00,540
+في ندي ملاحظة مهمة وأنا بدي أبدأ منها إنه أي
+
+480
+00:33:00,540 --> 00:33:04,880
+volume بدي أحضره لازم ينحصر ما بين عشرة إلى ألف
+
+481
+00:33:04,880 --> 00:33:09,520
+microliter أقل من عشرة بتكونش كمية sensitive لما
+
+482
+00:33:09,520 --> 00:33:15,000
+أنا باشي باخدها بالـ pipette أكتر من ألف طبعا كمية
+
+483
+00:33:15,000 --> 00:33:20,500
+كبيرة ويعني هستهلك reagent كتير فيهافاحنا بنتحيل
+
+484
+00:33:20,500 --> 00:33:25,700
+على التخفيفات اللى عندى بحيث ان ما يكون التخفيف
+
+485
+00:33:25,700 --> 00:33:30,060
+بتجاوز هذا يعني عفوا ما بيكون ال volume بتجاوز ال
+
+486
+00:33:30,060 --> 00:33:35,420
+1000 احنا عارفين ان في التخفيفات العادية البسيطة
+
+487
+00:33:35,420 --> 00:33:39,280
+لما كنا نعمل مثلا 1 إلى 10 و 1 إلى 20 ماكناش نتغلب
+
+488
+00:33:39,280 --> 00:33:43,140
+يعني كنا نقول مثلا 1 إلى 10 بتصير 1 إلى 9 diluent
+
+489
+00:33:43,140 --> 00:33:47,020
+و باجي بدرب في رقم ممكن أقول 100 إلى 900 و باخد ال
+
+490
+00:33:47,020 --> 00:33:50,460
+volume اللى بديها و بشتغل فيهالمشكلة لو كان
+
+491
+00:33:50,460 --> 00:33:55,180
+الأرقام كبيرة و جيت أضرب هيطلع معايا نواتج كبيرة
+
+492
+00:33:55,180 --> 00:33:58,200
+هيطلع معايا حاجات بالألاف طبعا احنا قلنا لا بدنا
+
+493
+00:33:58,200 --> 00:34:01,180
+نستهلك كميات كبيرة من الـ reagent فأنا في سبيل أني
+
+494
+00:34:01,180 --> 00:34:05,380
+أقلل كمية المستهلكة من الـ reagent بدي أتعلم الـ
+
+495
+00:34:05,380 --> 00:34:09,660
+Serial Dilution الآن لو أجاني تخفيف مثلا 9 إلى 250
+
+496
+00:34:09,660 --> 00:34:13,940
+9 إلى 250 هذا إيش ما بدي أعمل فيه هتطلع معايا
+
+497
+00:34:13,940 --> 00:34:18,550
+أرقام كبيرة عشان هيك بدي أحاولأقسمه لجزئين حاصل
+
+498
+00:34:18,550 --> 00:34:23,550
+ضربهم 9 على 250 يعني بقول مثلا 9 إلى 25 في 1 على
+
+499
+00:34:23,550 --> 00:34:29,790
+10 أو 3 على 25 في 1 على .. في عفوا 3 إلى 10 أو
+
+500
+00:34:29,790 --> 00:34:33,410
+عندي أكتر من الخيار يعني رقمين حاصل ضربهم 9 رقمين
+
+501
+00:34:33,410 --> 00:34:36,690
+حاصل ضربهم 250 أو 3 أرقام يعني ممكن أعمل فيتيوبين
+
+502
+00:34:36,690 --> 00:34:40,850
+أو في 3 قنابيب الآن باخد ال sample بعمل أول تخفيف
+
+503
+00:34:40,850 --> 00:34:47,060
+اللي هو 9 إلى 25 هذاعملته هنا عن طريق 90 µL من الـ
+
+504
+00:34:47,060 --> 00:34:52,320
+«سامبل» و160 µL من الـ «ديليوينت» هلأ بعد ما حضرته
+
+505
+00:34:52,320 --> 00:34:57,460
+هذا هو نفسه بدي أعمله mixing و آخد منه في القنبوب
+
+506
+00:34:57,460 --> 00:35:01,640
+التاني أعمل تخفيف 1 ل 10 هلأ هذه القنبوبة قداش
+
+507
+00:35:01,640 --> 00:35:07,640
+تركيزها صار 9 إلى 25 أجابت أخدت منها 100 µL ل 900
+
+508
+00:35:07,640 --> 00:35:13,870
+اللي هو 1 إلى 10 فهذه القنبوبةظاهريًا تركيزها 1
+
+509
+00:35:13,870 --> 00:35:19,350
+إلى 10 صح لكن فعليًا الـ 1 إلى 10 هدول أجوا من 9
+
+510
+00:35:19,350 --> 00:35:25,070
+إلى 25 فترخفيفها هيكون 9 إلى 250 هذا السفر نازل هي
+
+511
+00:35:25,070 --> 00:35:30,070
+9 إلى 250 ليش؟ لأن حاصل ضرب تخفيفها في تخفيف
+
+512
+00:35:30,070 --> 00:35:32,990
+الأنبوبة اللي قبلها هيك في الـ Serial Dilution أي
+
+513
+00:35:32,990 --> 00:35:36,870
+أنبوبة تخفيفها بيكون عبارة عن حاصل ضرب كل القنابيب
+
+514
+00:35:36,870 --> 00:35:42,980
+اللي قبلها لو كان عندي 10 قنابيبمثال آخر على الـ
+
+515
+00:35:42,980 --> 00:35:46,160
+Serial Dilution هنا بقولك حضري للـ Serial Dilution
+
+516
+00:35:46,160 --> 00:35:50,300
+1 إلى 1000 طبعا بالطريقة الـ Direct مش هتظبط الـ 1
+
+517
+00:35:50,300 --> 00:35:53,900
+إلى 1000 بقسمها 1 إلى 10 في 1 إلى 10 في 1 إلى 10
+
+518
+00:35:53,900 --> 00:35:58,040
+يعني بدي أحضر 3 أنابيب بتخفيفات 1 إلى 10 وفي كل
+
+519
+00:35:58,040 --> 00:36:02,300
+أنبوبة بدي أخد نسبة الـ 1 من اللي قبلها الأنبوبة
+
+520
+00:36:02,300 --> 00:36:06,700
+الأولى 100 إلى 900 باخد في الأنبوبة اللي بعدها 100
+
+521
+00:36:06,700 --> 00:36:10,800
+من هذه على 900برضه من ال saline أو من ال diluent
+
+522
+00:36:10,800 --> 00:36:16,180
+اللى بيكون و باخد من هذه 100 على 900 saline طبعا
+
+523
+00:36:16,180 --> 00:36:20,700
+هذه 1 ل 10 و هذه 1 ل 10 1 ل 10 ف1 ل 10 هذه بيكون
+
+524
+00:36:20,700 --> 00:36:25,260
+تخفيفها قداش 1 إلى 100 و هذه كمان 1 إلى 10 ف1 إلى
+
+525
+00:36:25,260 --> 00:36:29,120
+10 ف1 إلى 10 هتكون عاش 1 إلى 100 مثال على ال
+
+526
+00:36:29,120 --> 00:36:33,890
+serial dilution برضهاللي هو كيف انا أحضر 1 على 64
+
+527
+00:36:33,890 --> 00:36:39,250
+في عندك 1 إلى 4 و بعدين كمان 1 إلى 4 و 1 إلى 4 مش
+
+528
+00:36:39,250 --> 00:36:42,050
+شرط بنات الأرقام تبقى نفسها يعني ممكن أخد 1 إلى 4
+
+529
+00:36:42,050 --> 00:36:47,850
+1 إلى 8 1 إلى 2 أعتقد بتطلع المهم يعني مش شرط يكون
+
+530
+00:36:47,850 --> 00:36:50,310
+نفس الرقم ماتعتقدوش أنه لازم كلهم يكونوا نفس
+
+531
+00:36:50,310 --> 00:36:54,230
+النسبة لأ المهم أرقام تطلع في النهاية لما أضربها
+
+532
+00:36:54,230 --> 00:36:58,810
+التخفيف اللي أنا محتاجة هنا عمل تخفيف 1 إلى 4 100
+
+533
+00:36:58,810 --> 00:37:03,100
+إلى 300 تخفيف 1 إلى 4100 إلى 300 وهنا كمان 100 إلى
+
+534
+00:37:03,100 --> 00:37:08,260
+300 يعطيكوا ألف عافية هيك إحنا بنكون أنجزنا جزئية
+
+535
+00:37:08,260 --> 00:37:11,800
+ال agglutination بدون لسه أي application يعني لسه
+
+536
+00:37:11,800 --> 00:37:15,060
+الفحصات اللي بتنعمل على ال agglutination ماشغلناش
+
+537
+00:37:15,060 --> 00:37:21,680
+فيها حاجة حكينا بس عن فحص ال hemagglutination اللي
+
+538
+00:37:21,680 --> 00:37:24,920
+هو التجربة اللي عملناها اللي بتحديد ال title لـ
+
+539
+00:37:24,920 --> 00:37:26,640
+Antibiotics يعطيكوا ألف عافية
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/puJoH0Q5i1w_raw.json b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/puJoH0Q5i1w_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..4814e51383b271e56df25554e90b8c1db054f023
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/puJoH0Q5i1w_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 2768, "start": 1.16, "end": 27.68, "text": "بسم الله الرحمن الرحيم إن شاء الله رب العالمين راح نكون معاكم في مساق علم المناعة والأمثال العملي وراح ناخد اليوم أول موضوع من موضوعاتنا حناخد فكرة بسيطة يعني كمقدمة عن الـ Antigen و الـ Antibody و الـ Antigen Antibody Reactions عشان نوصل لأول مجموعة من الفحوصات", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 36145, 13412, 16606, 21984, 12602, 3555, 18863, 45340, 9957, 12602, 39319, 8717, 30544, 20449, 995, 24793, 8978, 47524, 995, 4587, 11203, 2304, 9673, 8315, 27884, 16070, 10721, 2304, 12984, 6027, 18863, 2304, 20292, 4032, 23557, 5016, 8717, 47283, 3215, 45595, 20498, 5551, 12610, 3714, 2407, 11242, 45367, 9154, 3714, 2407, 11242, 45367, 9307, 8315, 11331, 1863, 47283, 3215, 6156, 4117, 25720, 4724, 3794, 1829, 9566, 3660, 37495, 22653, 9122, 2304, 28543, 46007, 18871, 2423, 39184, 5130, 3213, 4032, 2423, 39184, 5130, 897, 843, 4032, 2423, 39184, 5130, 3213, 5130, 897, 843, 1300, 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"probability": 0.923095703125}, {"start": 6.16, "end": 6.5, "word": " نكون", "probability": 0.974609375}, {"start": 6.5, "end": 6.88, "word": " معاكم", "probability": 0.84326171875}, {"start": 6.88, "end": 7.16, "word": " في", "probability": 0.9375}, {"start": 7.16, "end": 8.12, "word": " مساق", "probability": 0.96337890625}, {"start": 8.12, "end": 8.44, "word": " علم", "probability": 0.946044921875}, {"start": 8.44, "end": 8.9, "word": " المناعة", "probability": 0.8924153645833334}, {"start": 8.9, "end": 9.5, "word": " والأمثال", "probability": 0.76357421875}, {"start": 9.5, "end": 10.04, "word": " العملي", "probability": 0.9300130208333334}, {"start": 10.04, "end": 11.64, "word": " وراح", "probability": 0.8204752604166666}, {"start": 11.64, "end": 11.98, "word": " ناخد", "probability": 0.9853515625}, {"start": 11.98, "end": 12.32, "word": " اليوم", "probability": 0.7734375}, {"start": 12.32, "end": 12.66, "word": " أول", "probability": 0.96337890625}, {"start": 12.66, "end": 13.24, 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"probability": 0.55078125}, {"start": 621.31, "end": 621.57, "word": " the", "probability": 0.890625}, {"start": 621.57, "end": 621.87, "word": " rate", "probability": 0.95849609375}, {"start": 621.87, "end": 622.11, "word": " of", "probability": 0.9814453125}, {"start": 622.11, "end": 622.27, "word": " the", "probability": 0.56884765625}, {"start": 622.27, "end": 622.73, "word": " increase", "probability": 0.77734375}, {"start": 622.73, "end": 623.27, "word": " in", "probability": 0.94189453125}, {"start": 623.27, "end": 623.83, "word": " turbidity", "probability": 0.9765625}, {"start": 623.83, "end": 625.23, "word": " is", "probability": 0.93994140625}, {"start": 625.23, "end": 625.93, "word": " inversely", "probability": 0.85302734375}, {"start": 625.93, "end": 626.47, "word": " proportional", "probability": 0.9326171875}, {"start": 626.47, "end": 626.97, "word": " of", "probability": 0.87890625}, {"start": 626.97, "end": 627.15, "word": " the", "probability": 0.93408203125}, 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agglutination with no agglutination being observed at any higher dilution يعني آخر واحدة هتعطيني dilution بعد هيك نهائيًا مش هيبين أي agglutination لو أنا زودت التخفيف فهذا بعتبره الـTiter The term is used in surgical reactions and is determined by preparing serial dilution تعلم نقولنا كيف", "tokens": [9566, 3555, 3615, 995, 14111, 6225, 18513, 3660, 14111, 39894, 30544, 4210, 449, 34051, 36632, 6225, 9957, 3660, 41850, 4724, 8592, 2655, 17082, 1211, 25894, 11296, 5130, 897, 843, 300, 920, 1874, 294, 623, 7191, 325, 2486, 13672, 1829, 8032, 2655, 5172, 11242, 1211, 37279, 9566, 9957, 1829, 623, 7191, 325, 2486, 365, 572, 623, 7191, 325, 2486, 885, 13095, 412, 604, 2946, 11504, 1448, 37495, 22653, 19753, 34740, 36764, 24401, 3660, 8032, 2655, 3615, 9566, 9957, 1829, 11504, 1448, 39182, 39896, 4117, 8717, 3224, 16373, 1829, 14111, 995, 37893, 39896, 3555, 9957, 36632, 623, 7191, 325, 2486, 45164, 41850, 30767, 23328, 2655, 16712, 9778, 5172, 33911, 6156, 3224, 15730, 4724, 34268, 26890, 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2211.67, "end": 2212.15, "word": " المهم", "probability": 0.977783203125}, {"start": 2212.15, "end": 2212.67, "word": " أرقام", "probability": 0.990234375}, {"start": 2212.67, "end": 2213.03, "word": " تطلع", "probability": 0.9666748046875}, {"start": 2213.03, "end": 2213.15, "word": " في", "probability": 0.93212890625}, {"start": 2213.15, "end": 2213.43, "word": " النهاية", "probability": 0.9051106770833334}, {"start": 2213.43, "end": 2213.65, "word": " لما", "probability": 0.88720703125}, {"start": 2213.65, "end": 2214.23, "word": " أضربها", "probability": 0.9530029296875}, {"start": 2214.23, "end": 2215.03, "word": " التخفيف", "probability": 0.8885498046875}, {"start": 2215.03, "end": 2215.23, "word": " اللي", "probability": 0.960205078125}, {"start": 2215.23, "end": 2215.51, "word": " أنا", "probability": 0.61376953125}, {"start": 2215.51, "end": 2216.37, "word": " محتاجة", "probability": 0.8526611328125}, {"start": 2216.37, "end": 2217.21, "word": " هنا", "probability": 0.865234375}, {"start": 2217.21, "end": 2217.49, "word": " عمل", "probability": 0.82568359375}, {"start": 2217.49, "end": 2217.85, "word": " تخفيف", "probability": 0.9349365234375}, {"start": 2217.85, "end": 2218.07, "word": " 1", "probability": 0.9794921875}, {"start": 2218.07, "end": 2218.21, "word": " إلى", "probability": 0.96435546875}, {"start": 2218.21, "end": 2218.53, "word": " 4", "probability": 0.98681640625}, {"start": 2218.53, "end": 2218.81, "word": " 100", "probability": 0.49462890625}, {"start": 2218.81, "end": 2219.01, "word": " إلى", "probability": 0.9853515625}, {"start": 2219.01, "end": 2219.49, "word": " 300", "probability": 0.982421875}, {"start": 2219.49, "end": 2219.93, "word": " تخفيف", "probability": 0.97265625}, {"start": 2219.93, "end": 2220.15, "word": " 1", "probability": 0.9853515625}, {"start": 2220.15, "end": 2220.25, "word": " إلى", "probability": 0.9716796875}, {"start": 2220.25, "end": 2220.55, "word": " 4", "probability": 0.94580078125}], 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" 300", "probability": 0.982421875}, {"start": 2223.64, "end": 2224.64, "word": " يعطيكوا", "probability": 0.8453125}, {"start": 2224.64, "end": 2224.88, "word": " ألف", "probability": 0.876220703125}, {"start": 2224.88, "end": 2225.28, "word": " عافية", "probability": 0.9638671875}, {"start": 2225.28, "end": 2225.6, "word": " هيك", "probability": 0.65625}, {"start": 2225.6, "end": 2225.9, "word": " إحنا", "probability": 0.7781575520833334}, {"start": 2225.9, "end": 2226.42, "word": " بنكون", "probability": 0.9560546875}, {"start": 2226.42, "end": 2227.2, "word": " أنجزنا", "probability": 0.975341796875}, {"start": 2227.2, "end": 2228.26, "word": " جزئية", "probability": 0.9136962890625}, {"start": 2228.26, "end": 2228.8, "word": " ال", "probability": 0.94580078125}, {"start": 2228.8, "end": 2229.54, "word": " agglutination", "probability": 0.77398681640625}, {"start": 2229.54, "end": 2230.02, "word": " بدون", "probability": 0.955322265625}, {"start": 2230.02, "end": 2230.34, "word": " لسه", "probability": 0.9212239583333334}, {"start": 2230.34, "end": 2230.52, "word": " أي", "probability": 0.84716796875}, {"start": 2230.52, "end": 2231.08, "word": " application", "probability": 0.95654296875}, {"start": 2231.08, "end": 2231.44, "word": " يعني", "probability": 0.9111328125}, {"start": 2231.44, "end": 2231.8, "word": " لسه", "probability": 0.9908854166666666}, {"start": 2231.8, "end": 2232.46, "word": " الفحصات", "probability": 0.93701171875}, {"start": 2232.46, "end": 2232.6, "word": " اللي", "probability": 0.915283203125}, {"start": 2232.6, "end": 2233.1, "word": " بتنعمل", "probability": 0.866943359375}, {"start": 2233.1, "end": 2233.28, "word": " على", "probability": 0.63134765625}, {"start": 2233.28, "end": 2233.4, "word": " ال", "probability": 0.93896484375}, {"start": 2233.4, "end": 2234.12, "word": " agglutination", "probability": 0.9344482421875}, {"start": 2234.12, "end": 2235.06, "word": " ماشغلناش", "probability": 0.944091796875}, {"start": 2235.06, "end": 2235.3, "word": " فيها", "probability": 0.99169921875}, {"start": 2235.3, "end": 2235.74, "word": " حاجة", "probability": 0.99853515625}, {"start": 2235.74, "end": 2236.3, "word": " حكينا", "probability": 0.9432373046875}, {"start": 2236.3, "end": 2236.64, "word": " بس", "probability": 0.984375}, {"start": 2236.64, "end": 2236.86, "word": " عن", "probability": 0.9921875}, {"start": 2236.86, "end": 2237.38, "word": " فحص", "probability": 0.9793294270833334}, {"start": 2237.38, "end": 2238.32, "word": " ال", "probability": 0.9716796875}, {"start": 2238.32, "end": 2240.04, "word": " hemagglutination", "probability": 0.8892578125}, {"start": 2240.04, "end": 2241.68, "word": " اللي", "probability": 0.96142578125}, {"start": 2241.68, "end": 2241.88, "word": " هو", "probability": 0.96875}, {"start": 2241.88, "end": 2242.36, "word": " التجربة", "probability": 0.9700927734375}, {"start": 2242.36, "end": 2242.46, "word": " اللي", "probability": 0.969970703125}, {"start": 2242.46, "end": 2242.86, "word": " عملناها", "probability": 0.99072265625}, {"start": 2242.86, "end": 2242.98, "word": " اللي", "probability": 0.961669921875}, {"start": 2242.98, "end": 2243.38, "word": " بتحديد", "probability": 0.80072021484375}, {"start": 2243.38, "end": 2243.46, "word": " ال", "probability": 0.82275390625}, {"start": 2243.46, "end": 2243.78, "word": " title", "probability": 0.61572265625}, {"start": 2243.78, "end": 2244.92, "word": " لـ", "probability": 0.4732666015625}, {"start": 2244.92, "end": 2245.58, "word": " Antibiotics", "probability": 0.6168212890625}, {"start": 2245.58, "end": 2246.08, "word": " يعطيكوا", "probability": 0.8759765625}, {"start": 2246.08, "end": 2246.26, "word": " ألف", "probability": 0.97119140625}, {"start": 2246.26, "end": 2246.64, "word": " عافية", "probability": 0.9845377604166666}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2249.4563125, "duration_after_vad": 2211.459374999994}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/rTh-VWmrZ78_postprocess.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/rTh-VWmrZ78_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..15a1b4193404ae02e13b4af9b37461e8bc988650
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/rTh-VWmrZ78_postprocess.srt
@@ -0,0 +1,1968 @@
+1
+00:00:01,400 --> 00:00:06,740
+بسم الله الرحمن الرحيم موضوع هذه المحاضرة يتكلم عن
+
+2
+00:00:06,740 --> 00:00:11,680
+مجموعة من الـ organism التي تسبب الـ abortion
+
+3
+00:00:11,680 --> 00:00:19,900
+اختصرت في torch torch هي اختصار لـ toxoplasmosis
+
+4
+00:00:19,900 --> 00:00:27,360
+others, rubella, cytomegalovirus, herbs هذه بعض ال
+
+5
+00:00:27,360 --> 00:00:31,730
+organisms التي تسبب الـ abortionThe five
+
+6
+00:00:31,730 --> 00:00:34,870
+categories of organisms whose antibodies are
+
+7
+00:00:34,870 --> 00:00:38,030
+measured by the torch test are grouped together
+
+8
+00:00:38,030 --> 00:00:41,250
+because they can cause abortion for pregnant women
+
+9
+00:00:41,250 --> 00:00:45,750
+and or birth defects in newborn يعني هذه المجموعة
+
+10
+00:00:45,750 --> 00:00:51,510
+من الفحوصات أو هذه المجموعة من الـ organisms بنحدد
+
+11
+00:00:51,510 --> 00:00:55,750
+الـ antibodies لإلها غالبا بتنطلب مع بعض لما يصير
+
+12
+00:00:55,750 --> 00:01:02,150
+recurrent abortion أو يصير فيbirth defect يعني
+
+13
+00:01:02,150 --> 00:01:06,550
+يبقى الستة هذه مثلا أنجبات مرة أو تنتين والأطفال
+
+14
+00:01:06,550 --> 00:01:10,110
+ييجوا عندهم تشوه أو عيب خلقي فممكن تنطلب هذه
+
+15
+00:01:10,110 --> 00:01:14,230
+الفحوصات عشان نتأكد من عدم وجود أي واحد منهم يعني
+
+16
+00:01:14,230 --> 00:01:17,850
+هذه الأشياء ممكن تسبب abortion وفي بعض الأحيان لو
+
+17
+00:01:17,850 --> 00:01:24,250
+ما صار abortion وكمل الحمل بيتمل مع تشوه خلقي أول
+
+18
+00:01:24,250 --> 00:01:28,490
+واحد له تكسب Lasmosis ثاني واحد others بيشمل
+
+19
+00:01:29,050 --> 00:01:32,990
+Chlamydia, Syphilis, Hepatitis B, Coxsackievirus,
+
+20
+00:01:33,130 --> 00:01:37,490
+Ibstambar virus, Varicella-zoster virus and Human
+
+21
+00:01:37,490 --> 00:01:44,170
+Box virus الـR روبيلة, Cytomegalovirus الـC, Herbs
+
+22
+00:01:44,170 --> 00:01:45,290
+الـH
+
+23
+00:01:51,320 --> 00:01:55,640
+طبعاً هناك مجموعة كبيرة من أسباب الـ abortion يعني
+
+24
+00:01:55,640 --> 00:01:59,820
+فيه أشياء ما إلها علاقة أصلا بالـ organisms وفيه
+
+25
+00:01:59,820 --> 00:02:04,100
+أشياء إلها علاقة بالـ organisms الأشياء اللي إلها
+
+26
+00:02:04,100 --> 00:02:08,040
+علاقة بالـ organisms هي قد تكون viral أو non-viral
+
+27
+00:02:08,040 --> 00:02:12,040
+بعض الـ viruses اللي ممكن تسبب الـ abortion زي الـ
+
+28
+00:02:12,040 --> 00:02:17,320
+cytomegalovirus روبيلا، herpes، الـ non-virus زي
+
+29
+00:02:17,320 --> 00:02:21,180
+الكلاميديا والتكسوفالـ Plasma Gondii التوكسو
+
+30
+00:02:21,180 --> 00:02:25,040
+بلازما هذه عبارة عن براسايت لكلاميديا هي غالبا
+
+31
+00:02:25,040 --> 00:02:31,360
+بكتيريا عندها بعض الصفات من الفيروس نيجي
+
+32
+00:02:31,360 --> 00:02:35,740
+بداية للـ Toxoplasmosis التوكسو بلازموزز عبارة عن
+
+33
+00:02:35,740 --> 00:02:42,200
+مرض يسببه طفل اللي هو التوكسو بلازما Gondii يعتبر
+
+34
+00:02:42,200 --> 00:02:46,080
+zoonotic disease اش يعني zoonotic disease؟
+
+35
+00:02:46,080 --> 00:02:50,220
+zoonotic diseaseتعني بإن هذا المرض ينتقل من
+
+36
+00:02:50,220 --> 00:02:54,540
+الحيوان إلى الإنسان ويسبب له الأمراض Caused by
+
+37
+00:02:54,540 --> 00:02:58,700
+infection with a protozoa Toxoplasma gondii
+
+38
+00:02:58,700 --> 00:03:03,960
+Toxoplasmosis في البداية ممكن يسبب Flu-like
+
+39
+00:03:03,960 --> 00:03:08,740
+symptoms يعني ممكن يسبب أعراض خفيفة زي أعراض الـ
+
+40
+00:03:08,740 --> 00:03:14,340
+Influenza عند بعض الناس ناس أخرى يعني ممكن يجيهم
+
+41
+00:03:14,340 --> 00:03:20,160
+هذا الطفلبدون ما يسبب عندهم أي أعراض يعني بيجي
+
+42
+00:03:20,160 --> 00:03:24,980
+وبيخلص بدون ما يسبب عندهم أي symptoms for infants
+
+43
+00:03:24,980 --> 00:03:27,980
+born to infected mother and for people with
+
+44
+00:03:27,980 --> 00:03:31,640
+weakened immune system toxoplasmosis can cause
+
+45
+00:03:31,640 --> 00:03:35,720
+extremely serious complications وين بتكمل المشكلة
+
+46
+00:03:35,720 --> 00:03:42,760
+لو كان أصيبت ست حامل بهذا الطفل أو أصيب فيه إنسان
+
+47
+00:03:42,760 --> 00:03:47,030
+من ذوي المناعة المنخفضةهنا ممكن يعمل عندنا serious
+
+48
+00:03:47,030 --> 00:03:52,030
+complications ممكن يعمل عندنا أعراض ومضاعفات خطيرة
+
+49
+00:03:52,030 --> 00:03:55,430
+أول
+
+50
+00:03:55,430 --> 00:03:59,910
+حاجة نحكي على الـ Toxoplasma Gondii الـ Toxoplasma
+
+51
+00:03:59,910 --> 00:04:03,490
+Gondii عبارة عن obligate intracellular parasite
+
+52
+00:04:03,490 --> 00:04:10,230
+بعيش في داخل الخلية طبعا هذا الطفل عنده القدرة على
+
+53
+00:04:10,230 --> 00:04:14,740
+أنه يصيب كلالـ warm-blooded animals اللي هي كل
+
+54
+00:04:14,740 --> 00:04:17,540
+الحيوانات ذوات الدم الحار يعني lack of host
+
+55
+00:04:17,540 --> 00:04:22,920
+specificity مالهاش host محدد تعتبر ال cats هي ال
+
+56
+00:04:22,920 --> 00:04:25,900
+definitive host إيش يعني definitive host؟ يعني
+
+57
+00:04:25,900 --> 00:04:30,700
+بيعتبروا ال host النهائي اللي بيكمل نضوج ال
+
+58
+00:04:30,700 --> 00:04:35,960
+parasite فيه أو الطفال فيه وبيقدر في هذه المرحلة
+
+59
+00:04:35,960 --> 00:04:39,600
+أنه يعمل reproductionفبالتالي في ال «cats» هو
+
+60
+00:04:39,600 --> 00:04:43,060
+بيتكاثر يعني هو ممكن يصيب الحيوانات الأخرى لكن لا
+
+61
+00:04:43,060 --> 00:04:48,240
+يتكاثر فيها هو ينتقل إلها و بتكون كوسيط للنقل مثلا
+
+62
+00:04:48,240 --> 00:04:53,240
+أو مثلا ممكن ينتقل للأبقار ع سبيل المثال لو انتقل
+
+63
+00:04:53,240 --> 00:04:56,880
+للأبقار ممكن ينتقل إلى الإنسان ويصيبه يعمل عنده
+
+64
+00:04:56,880 --> 00:05:02,200
+مشاكل لكن عملية التكاثر بتكون في ال «cat» عشان هيك
+
+65
+00:05:02,200 --> 00:05:07,270
+بيسموها جرثومة خاصة بالقطط و بتسبب الإجهاضTissue
+
+66
+00:05:07,270 --> 00:05:10,330
+cyst formed in any organ especially brain, eyes
+
+67
+00:05:10,330 --> 00:05:13,950
+and strength muscles هذه لو انتقلت إلى الكائن الحي
+
+68
+00:05:13,950 --> 00:05:18,490
+الإنسان أو الحيوان اللي هي الـ cyst بتعيش في
+
+69
+00:05:18,490 --> 00:05:23,750
+الانسشة ممكن في الـbrain، في العين، في ال strength
+
+70
+00:05:23,750 --> 00:05:28,170
+muscles، في العضلات، في أي مكان من الجسم ممكن تعيش
+
+71
+00:05:28,170 --> 00:05:31,890
+وتستقر وتعمل مضاعفات ومشايا هذا الطفل زي ما قلت
+
+72
+00:05:31,890 --> 00:05:35,370
+لكم بيعيش في ال intestine لل cat وهناك بتم تكاثره
+
+73
+00:05:35,860 --> 00:05:39,660
+بطلع الطور المعدى الطور المعدى اللي هو الـ Oocyste
+
+74
+00:05:39,660 --> 00:05:44,360
+الـ Oocyste هذا قد يصيب الأم الحامل مباشرة عن طريق
+
+75
+00:05:44,360 --> 00:05:50,460
+تلوث الطعام بيه الـ Fecal Cat طبعا إذا أصاب الأم
+
+76
+00:05:50,460 --> 00:05:54,480
+الحامل هيعمل مضاعفات عند الجنين قد يصيب مثلا
+
+77
+00:05:54,480 --> 00:06:00,750
+الفئرانوممكن ترجع من تاني إلى القطط قد تصيب
+
+78
+00:06:00,750 --> 00:06:04,230
+الحيوانات الأخرى اللي الإنسان بيتغذى عليها زي
+
+79
+00:06:04,230 --> 00:06:09,530
+الأبطار والأغنام إذا أصاب هذه الحيوانات ممكن تنتقل
+
+80
+00:06:09,530 --> 00:06:14,130
+من هذه الحيوانات عبر التعامل مع اللحوم الغير مطهوة
+
+81
+00:06:14,130 --> 00:06:18,410
+جيدا وتنتقل إلى الإنسان يعني قد تنتقل مباشرة الـ
+
+82
+00:06:18,410 --> 00:06:22,390
+Oocyte إلى الإنسان أو قد تنتقل عبر وسيط من
+
+83
+00:06:22,390 --> 00:06:27,010
+الحيوانات تدخل هذه لجسم الحيوانوتستقر في ال
+
+84
+00:06:27,010 --> 00:06:31,530
+muscles بتاعته وبعد هيك تنتقل لإنسان أخذ هذه
+
+85
+00:06:31,530 --> 00:06:37,110
+العضلات الغير مطهوة جيدا أو اللحم نيجي لطرق انتقال
+
+86
+00:06:37,110 --> 00:06:42,750
+العدوى كيف تنتقل العدوى إلى الإنسان أول حاجة ممكن
+
+87
+00:06:42,750 --> 00:06:48,150
+تنتقل من اللحم الغير مطهو جيدا يعني لو اللحمة مثلا
+
+88
+00:06:48,150 --> 00:06:52,520
+ماكنتش متعرضة لدرجة حرارة مناسبةأو مشتقات اللحوم
+
+89
+00:06:52,520 --> 00:06:57,880
+زي الـ Luncheon والسجق والبرجر هذه الأشياء لو ما
+
+90
+00:06:57,880 --> 00:07:02,820
+كانت مطهوة بالشكل الجيد ممكن تؤدي إلى نقل الطفل
+
+91
+00:07:02,820 --> 00:07:07,960
+شغلة تانية لو أنا اللحوم الغير مطهوة عند التعامل
+
+92
+00:07:07,960 --> 00:07:12,560
+معها وتقطيعها وغسلها الأدوات اللي حطيتها فيها
+
+93
+00:07:12,560 --> 00:07:16,390
+ماكنتش منضفاها كويس زيالـ cutting board مثلًا لوحة
+
+94
+00:07:16,390 --> 00:07:20,450
+التقطيع هذه ممكن يعلق فيها هذا الطفيل وبعد هيك
+
+95
+00:07:20,450 --> 00:07:25,270
+ينتقل إلى الخضار والاشياء اللي بتأكل fresh ما
+
+96
+00:07:25,270 --> 00:07:28,090
+بتنطبخ فبالتالي ممكن تصير الإصابة ك cross
+
+97
+00:07:28,090 --> 00:07:31,470
+-contamination drinking water contaminated with
+
+98
+00:07:31,470 --> 00:07:35,950
+toxoplasma gondii لو الإنسان شرب ميه ملوثة بهذا
+
+99
+00:07:35,950 --> 00:07:40,730
+الطفيل ممكن يصاب بالعدل mother to childcongenital
+
+100
+00:07:40,730 --> 00:07:45,570
+transmission ممكن ينتقل برضه من الأم إلى الطفل إذا
+
+101
+00:07:45,570 --> 00:07:49,070
+كانت مثلا الأم مربي بساس والبساس هدول انتقلت
+
+102
+00:07:49,070 --> 00:07:52,890
+العدوى من القطة إلى الأم وممكن تنتقل إلى الطفل
+
+103
+00:07:52,890 --> 00:07:55,670
+accidentally swallowing the parasite through
+
+104
+00:07:55,670 --> 00:07:59,570
+contact with cat feces that contain toxoplasma
+
+105
+00:07:59,570 --> 00:08:03,270
+تمام؟ receiving an infected organ transplant or
+
+106
+00:08:03,270 --> 00:08:08,000
+infected blood via transfusionبس يعني على الرغم إن
+
+107
+00:08:08,000 --> 00:08:11,480
+ممكن تصير هذه الشغلة لكن نادرة من خلال نقل أعضاء
+
+108
+00:08:11,480 --> 00:08:19,080
+أو نقل دم طيب
+
+109
+00:08:19,080 --> 00:08:22,580
+الآن السؤال اللي بيترح نفسه is toxoplasmosis
+
+110
+00:08:22,580 --> 00:08:28,120
+serious عادة toxoplasmosis يعني ما بيخوف ليش؟ لأن
+
+111
+00:08:28,120 --> 00:08:31,120
+ال immune system عنده القدرة على إنه يتعامل معاه
+
+112
+00:08:31,120 --> 00:08:36,370
+ويقضي على ال infection بدون أن يحدث مضاعفاتعادة
+
+113
+00:08:36,370 --> 00:08:40,250
+بعد ال infection معظم الناس بيظل عندهم مناعة ال
+
+114
+00:08:40,250 --> 00:08:45,250
+IGG بتظل عندهم for the rest of life طول حياتهم
+
+115
+00:08:45,250 --> 00:08:49,650
+بيظل ال IGG موجود لكن في بعض الأحيان ممكن يكون
+
+116
+00:08:49,650 --> 00:08:53,290
+serious problems عند مين؟ عند الستات الحوامل
+
+117
+00:08:53,290 --> 00:08:58,290
+والناس اللي منعتهم ضعيفة ال IGG لل congenital
+
+118
+00:08:58,290 --> 00:09:03,820
+toxoplasmosis اللي هو بينتقل من الأم إلى الطفلالآن
+
+119
+00:09:03,820 --> 00:09:07,700
+تقريبًا من 10 إلى 20% من الـ Pregnant Woman اللي
+
+120
+00:09:07,700 --> 00:09:12,180
+بتوصاب بتكسب لازماجوندياي تظهر عندها بعض الأعراض
+
+121
+00:09:12,180 --> 00:09:16,520
+معظم الأعراض اللي بتظهر حمّة بسيطة مع لمثا
+
+122
+00:09:16,520 --> 00:09:21,920
+دينوباثي تضخم في الغدد اللمفاوية الآن إذا أصيبت
+
+123
+00:09:21,920 --> 00:09:26,880
+الأم بتكسب لازماجوندياي خلال الحمل الطفالها ده
+
+124
+00:09:26,880 --> 00:09:29,740
+ممكن إنه ينتقل عبر الـ placenta إلى ال baby
+
+125
+00:09:30,530 --> 00:09:33,590
+وبالتالي infection may be transmitted to the fetus
+
+126
+00:09:33,590 --> 00:09:39,550
+transplacenta يعني أن طبابي بتوصلوا الـ Toxo أو
+
+127
+00:09:39,550 --> 00:09:43,950
+الطفال من خلال الـ Placenta طيب الطفل لما بيوصلوا
+
+128
+00:09:43,950 --> 00:09:47,990
+الطفال إيش ممكن يصير فيه؟ فهذا بيعتمد على في أي
+
+129
+00:09:47,990 --> 00:09:51,330
+شهر من الحمل الست أصيبة بقولك إذا كان ال infection
+
+130
+00:09:51,330 --> 00:09:56,530
+كانت في فترة قصيرة قبل الحمل تمام within a few
+
+131
+00:09:56,530 --> 00:09:59,370
+weeks before يعني في الأسبوع القليلة قبل فترة
+
+132
+00:09:59,370 --> 00:10:04,880
+الحملCarriers a 1% risk or below of transmission
+
+133
+00:10:04,880 --> 00:10:10,160
+to the baby يعني فرصة انتقالها إلى ال baby أقل من
+
+134
+00:10:10,160 --> 00:10:17,900
+1% تمام؟ لكن إذا وصلت لل baby حيصير فيه خطر من أن
+
+135
+00:10:17,900 --> 00:10:21,500
+يصير miscarriageيعني إذا فعلاً الجرثومة وصلت
+
+136
+00:10:21,500 --> 00:10:25,040
+للبابي هيبقى في احتمال كبير أن يصير abortion أو
+
+137
+00:10:25,040 --> 00:10:28,160
+miscarriage تمام؟ إذن هي بس الفرصة إنها توصل
+
+138
+00:10:28,160 --> 00:10:31,740
+للبابي أقل من 1% لكن في ال .. لو وصلت غالباً بيصير
+
+139
+00:10:31,740 --> 00:10:35,980
+إجهاض if infection was in the first trimester يعني
+
+140
+00:10:35,980 --> 00:10:40,260
+لو العتوى صارت في الأسبوع الأول من الحمل في ال ..
+
+141
+00:10:40,260 --> 00:10:43,340
+في ال trimester عفوا الأول من الحمل اللي هو أول
+
+142
+00:10:43,340 --> 00:10:49,110
+تلت شهورمن الأسبوع الأول للأسبوع الأتناش عادة
+
+143
+00:10:49,110 --> 00:10:54,750
+الستات اللي أصيبوا عشرة إلى خمستاشر في المية منهم
+
+144
+00:10:54,750 --> 00:10:58,810
+ممكن ينقلوها لل baby a baby infected at this stage
+
+145
+00:10:58,810 --> 00:11:02,510
+has a risk of being miscarried or stillbirth يعني
+
+146
+00:11:02,510 --> 00:11:06,590
+ممكن يصير abortion أو أنه يموت في داخل الرحم وبعد
+
+147
+00:11:06,590 --> 00:11:12,490
+هيك يصيرله abortionإذن كل ما اتقدمنا في شهور الحمل
+
+148
+00:11:12,490 --> 00:11:15,670
+كل ما كانت الخطورة على ال baby أكتر لغاية الآن
+
+149
+00:11:15,670 --> 00:11:22,030
+الفرصة قبل الحمل 1% فرصة انتقالها لل baby لكن في
+
+150
+00:11:22,030 --> 00:11:28,930
+ال first trimester من 10 إلى 15% طيب هنا لو ال
+
+151
+00:11:28,930 --> 00:11:32,630
+infection صارت في second trimester من الحمل يعني
+
+152
+00:11:32,630 --> 00:11:37,790
+في الأسبوع 13 إلى 28فرصة انتقالها للـ baby هتزيد
+
+153
+00:11:37,790 --> 00:11:42,970
+هتصير 25% لكن الـ baby اللي بيصاب في هذه المرحلة
+
+154
+00:11:42,970 --> 00:11:47,690
+غالبا ما بيصير له miscarriage وإنما بيظل موجود لكن
+
+155
+00:11:47,690 --> 00:11:52,030
+غالبا بيصير عنده تشوهات خلقية زي Hydrocephaly كبير
+
+156
+00:11:52,030 --> 00:11:56,150
+حجم الشمشمة تجمع سوائل فيها calcification of the
+
+157
+00:11:56,150 --> 00:11:59,970
+brain retinocarditis اللي هو inflammation of the
+
+158
+00:11:59,970 --> 00:12:02,770
+retina التهاب في شبكية العين قد يؤدي إلى العمى
+
+159
+00:12:03,180 --> 00:12:06,380
+microcephaly صغر حجم الجمجمة neurological
+
+160
+00:12:06,380 --> 00:12:09,740
+disorders مشاكل اللي لو انتقلت في الـ third
+
+161
+00:12:09,740 --> 00:12:14,280
+trimester في آخر تلت شهور من الحمل من 29 إلى 40
+
+162
+00:12:14,280 --> 00:12:19,540
+أسبوع هنا عادة الفرصة هتصير عالية للانتقال من 70
+
+163
+00:12:19,540 --> 00:12:25,100
+إلى 80% هتصير فرصة انتقال إلى ال baby هنا ال baby
+
+164
+00:12:25,100 --> 00:12:30,120
+مش هيصيرله غالبا مسكرج ولا حاجة وهينولد طبيعي لكن
+
+165
+00:12:30,120 --> 00:12:35,940
+عدد كبير منهمبيصير عندهم symptoms بعد الولادة يعني
+
+166
+00:12:35,940 --> 00:12:40,320
+ممكن يصير عندهم eye damage ممكن يصير عندهم بعض الـ
+
+167
+00:12:40,320 --> 00:12:45,420
+neurological problems أو disorders من الحاجات
+
+168
+00:12:45,420 --> 00:12:48,780
+الشائعة اللي ممكن تصير كمضاعفة للـ toxoplasmosis
+
+169
+00:12:48,780 --> 00:12:52,020
+سواء الـ congenital أو الـ acute infection اللي هو
+
+170
+00:12:52,020 --> 00:12:56,760
+الـ retinocarditis أو ocular toxoplasmosis عادةً
+
+171
+00:12:56,760 --> 00:12:59,440
+هذا بينتج من الـ reactivation of congenital
+
+172
+00:12:59,440 --> 00:13:05,000
+infectionيعني إعادة تنشيط للطفال or part of acute
+
+173
+00:13:05,000 --> 00:13:09,040
+infection كيف بيصير هذا؟ لما ال organism بيوصل
+
+174
+00:13:09,040 --> 00:13:13,640
+للعين قبر ال blood stream طبعا هناك ممكن تبقى
+
+175
+00:13:13,640 --> 00:13:17,500
+المناعة تحت الشخص كويسة يعني ال immune status
+
+176
+00:13:17,500 --> 00:13:25,100
+كويسة فبتلالي هتلاقي أن الطفال هيقعد في العين ومش
+
+177
+00:13:25,100 --> 00:13:30,310
+هيعمل مشاكل تمام؟الان في لحظة معينة ممكن تضعف
+
+178
+00:13:30,310 --> 00:13:34,170
+المناعة فلقيت لو ضعفت المناعة الطفل هذا هيتنشط
+
+179
+00:13:34,170 --> 00:13:38,710
+ويبدأ يطلق ال parasites تمام ال parasites هذه
+
+180
+00:13:38,710 --> 00:13:42,490
+هتعمل inflammatory response هيؤذي شبكية العين الان
+
+181
+00:13:42,490 --> 00:13:48,950
+فينا بقولك يعني انه كيف ايش اللي بيصير كرد فعل
+
+182
+00:13:48,950 --> 00:13:52,990
+لجهاز المناعة assist form و assist هذه مقاومة
+
+183
+00:13:52,990 --> 00:13:56,310
+لجهاز المناعةوالاتنين بيكونوا على الحياد يعني ولا
+
+184
+00:13:56,310 --> 00:13:59,710
+واحد فيهم بأذى التاني فتتحول ل chronic infection
+
+185
+00:13:59,710 --> 00:14:02,730
+ال cyst موجودة يعني لو الدكتور اتطلع على الشبكية
+
+186
+00:14:02,730 --> 00:14:09,570
+ممكن يشوف ال cyst في العين تمام whenever the host
+
+187
+00:14:09,570 --> 00:14:13,190
+immune function declines for any reason لأي سبب
+
+188
+00:14:13,190 --> 00:14:16,110
+اتغيرت ال host immune function ال cyst و ال
+
+189
+00:14:16,110 --> 00:14:18,890
+rupture ال cyst اللي اتكونت هذي هيصير لها rupture
+
+190
+00:14:19,390 --> 00:14:22,910
+وهي تطلع ال organism على ال retina على الشبكية
+
+191
+00:14:22,910 --> 00:14:26,970
+وبتعمل inflammatory process طبعا ال inflammatory
+
+192
+00:14:26,970 --> 00:14:31,870
+process ممكن تعمل lesion نتيجة التفاعل ممكن ال
+
+193
+00:14:31,870 --> 00:14:36,870
+healing يصير على الالشبكية نفسها وانتوا عارفين أي
+
+194
+00:14:36,870 --> 00:14:40,810
+حاجة عال الشبكية ممكن تعمل الاسكار وممكن تأثر على
+
+195
+00:14:40,810 --> 00:14:44,190
+القلبي ال diagnosis of toxoplasmosis الفحوصات يعني
+
+196
+00:14:44,190 --> 00:14:48,650
+قد تكون serological tests أو PCR أو ناخد مقطع من
+
+197
+00:14:48,650 --> 00:14:52,210
+النسيج histologic determination of the parasite و
+
+198
+00:14:52,210 --> 00:14:56,850
+بنسبغها بال immunobricosidase 2 و بنشوف ال
+
+199
+00:14:56,850 --> 00:14:59,970
+parasite إذا كان موجود ممكن نعمل isolation لل
+
+200
+00:14:59,970 --> 00:15:04,840
+organismفي طرق أخرى أقل شيوعا زي الـ Demonstration
+
+201
+00:15:04,840 --> 00:15:07,660
+of Antigen in Serum and Body Fluids إن ندور على
+
+202
+00:15:07,660 --> 00:15:10,700
+الـ Antigen مش على الـ Antibody فينا فحص اسمه A
+
+203
+00:15:10,700 --> 00:15:14,680
+Toxoplasmic Skin Test Antigen Specific Lymphocyte
+
+204
+00:15:14,680 --> 00:15:18,820
+Transformation فلقيت إحنا هركز بشكل أساسي على الـ
+
+205
+00:15:18,820 --> 00:15:22,840
+Serological Serological Test فينا فحصات سيرولوجي
+
+206
+00:15:22,840 --> 00:15:27,520
+كتير عملت عشان الـ Toxoplasmosisطبعاً بندور على
+
+207
+00:15:27,520 --> 00:15:30,820
+الـ Antibody إذا طلع عندنا الفحص positive المفروض
+
+208
+00:15:30,820 --> 00:15:35,740
+نشوف يعني هل هو IgG أو IgM؟ هل ال infection قديمة؟
+
+209
+00:15:35,740 --> 00:15:39,740
+هل هي مثلا recent infection؟ وهي اللي أثرت وعملت
+
+210
+00:15:39,740 --> 00:15:42,340
+abortion أو عملت تشوهات عند الجنين ولا لأ؟ لذا
+
+211
+00:15:42,340 --> 00:15:47,980
+لازم نحدد نوع الـ Antibody الموجود إذا كان فيه
+
+212
+00:15:47,980 --> 00:15:50,320
+أنشكة في التكسو أو الناس معاه أولاً الـ IgG
+
+213
+00:15:50,320 --> 00:15:57,270
+Antibodyالـ IgG Antibodies عادة بتظهر خلال أسبوع
+
+214
+00:15:57,270 --> 00:16:01,690
+إلى أسبوعين من الـ infection وبتوصل الـ peak من
+
+215
+00:16:01,690 --> 00:16:06,390
+شهر إلى شهرين ممكن بعد هيك تنزل لكن لا تنعدم يعني
+
+216
+00:16:06,390 --> 00:16:10,630
+ممكن تظلها طول الحياة وبيختلف هذا من شخص لشخص
+
+217
+00:16:10,630 --> 00:16:14,870
+القرق المستخدمة في قياس الـ IgG فيه أن السابين
+
+218
+00:16:14,870 --> 00:16:19,660
+فيلدمان دايتست إليزاimmunofluorescence assay and
+
+219
+00:16:19,660 --> 00:16:22,860
+modified direct agglutination test IGM antibodies
+
+220
+00:16:22,860 --> 00:16:29,260
+IGM antibodies عادة بترتفع من خمس أيام إلى أسبوع
+
+221
+00:16:29,260 --> 00:16:34,860
+بعد الـ acute infection بتوصل لـ maximum خلال واحد
+
+222
+00:16:34,860 --> 00:16:40,340
+وعشرين يوم وبتنزل أسرع من الـ IgG the most
+
+223
+00:16:40,340 --> 00:16:43,900
+commonly used test for the measurement of IGM برضه
+
+224
+00:16:43,900 --> 00:16:47,840
+الـ ELISA الimmune fluorescenceالـ Immunosorbent
+
+225
+00:16:47,840 --> 00:16:54,480
+Agglutination Assay الآن من الفحصات اللي بنكشف عن
+
+226
+00:16:54,480 --> 00:16:57,900
+الـ Antibodies من خلالها اللي هو Sabine Fieldman
+
+227
+00:16:57,900 --> 00:17:03,340
+-Dye Test الفحص فكرته بسيطة كتير أنه أنا بجيب عينة
+
+228
+00:17:03,340 --> 00:17:07,260
+الـ Serum و بجيب الطفل نفسه تكسب Plasma
+
+229
+00:17:07,260 --> 00:17:13,060
+Etrophosite بحط عينة الـ Serum مع الـ Etrophosite
+
+230
+00:17:13,060 --> 00:17:16,610
+مع complementتمام؟ الـ complement عشان يعمل
+
+231
+00:17:16,610 --> 00:17:20,610
+activation للـ antigen-antibody reaction هلقيت،
+
+232
+00:17:20,610 --> 00:17:24,570
+إذا كان الـ antibody موجود في عينة السيرام هيتفاعل
+
+233
+00:17:24,570 --> 00:17:28,170
+مع الـ trophocyte في وجود الـ complement، بتعرفي
+
+234
+00:17:28,170 --> 00:17:30,750
+إن الـ complement لما بتكون موجودة بتعمل license
+
+235
+00:17:30,750 --> 00:17:33,630
+للـ cell membrane إذا اتفاعل الـ antigen والـ
+
+236
+00:17:33,630 --> 00:17:37,450
+antibody واتنشطت الـ complement هيطلف الـ cell
+
+237
+00:17:37,450 --> 00:17:43,470
+membrane بتاع الـ toxin تمام؟لو كان الـ Antibody
+
+238
+00:17:43,470 --> 00:17:46,870
+مش موجود مش هيتم التفاعل و هيظل الـ Cell Membrane
+
+239
+00:17:46,870 --> 00:17:50,770
+كويس يعني مش هيطلع طيب أنا كيف بدي أستدل هل الـ
+
+240
+00:17:50,770 --> 00:17:56,570
+Cell Membrane ضاله Intact ولا صارله Lysis؟ عن طريق
+
+241
+00:17:56,570 --> 00:18:01,290
+إضافة صبغة الميسيليني بلو هلأ الميسيليني بلو
+
+242
+00:18:01,290 --> 00:18:05,410
+المفروض بتصبغ الخلية الكاملة إذا كانت خلية كاملة و
+
+243
+00:18:05,410 --> 00:18:08,890
+إلها Cell Membrane هيدخل الميسيليني بلو لداخلها و
+
+244
+00:18:08,890 --> 00:18:12,200
+يصبغها و مش هيطلع منهالكن لو كان الـ Cell Membrane
+
+245
+00:18:12,200 --> 00:18:17,660
+تالف بالتالي هتلاقي إنه الخلية مش هتنصبغ إذن
+
+246
+00:18:17,660 --> 00:18:21,080
+الخلية المصبوغة بتدل على إن العينة Negative مافيش
+
+247
+00:18:21,080 --> 00:18:24,640
+فيها Antibody الخلية الغير مصبوغة بتدل على إن
+
+248
+00:18:24,640 --> 00:18:28,600
+الخلية Positive يعني الـ Cell Membrane فقدت عن
+
+249
+00:18:28,600 --> 00:18:31,400
+طريق الـ Antibody الموجود في عينة الـ Serum دلنا
+
+250
+00:18:31,400 --> 00:18:34,780
+نشوف إيش موجودThis is based on the presence of
+
+251
+00:18:34,780 --> 00:18:37,720
+certain antibodies that prevent Mycelin Blue dye
+
+252
+00:18:37,720 --> 00:18:40,140
+from entering the cytoplasm of Toxoplasma
+
+253
+00:18:40,140 --> 00:18:43,800
+organisms.Patient serum is treated with Toxoplasma
+
+254
+00:18:43,800 --> 00:18:49,240
+trophozoite patient serum and complement as
+
+255
+00:18:49,240 --> 00:18:53,160
+activator and then incubated بعمل incubation بعد
+
+256
+00:18:53,160 --> 00:18:56,260
+ال incubation Mycelin Blue is added عشان أشوف هل
+
+257
+00:18:56,260 --> 00:18:59,230
+هتنصبه ولا مش هتنصبهإذا كانت الـ Antitoxin
+
+258
+00:18:59,230 --> 00:19:03,470
+Antibodies موجودة في السيروم لأن هذه الانتباطات تم
+
+259
+00:19:03,470 --> 00:19:07,750
+اكتشافها بـ Complement وكذلك برسايت ممبران تكسو
+
+260
+00:19:07,750 --> 00:19:11,890
+بلازمة تروفوزايت ليسوا مظهرين مظهرين ليسوا مظهرين
+
+261
+00:19:11,890 --> 00:19:15,810
+يعني نتيجة جيدة إذا لم يكن هناك انتباطات تروفوزايت
+
+262
+00:19:15,810 --> 00:19:21,110
+مع ممبران مستقل مظهرين ومظهرين تحت الميكروسكوب
+
+263
+00:19:21,110 --> 00:19:26,750
+اللي هي نتيجة أخرى للكشف عن الـ IgM Antibodies
+
+264
+00:19:27,310 --> 00:19:30,450
+التقنية هذه بتجمع ما بين الـ immunosorbent والـ
+
+265
+00:19:30,450 --> 00:19:34,930
+agglutination بتعتمد فكرتها كتير بسيطة إنه في عندى
+
+266
+00:19:34,930 --> 00:19:39,290
+ولات الول هذه على شكل U-shape دائرية القاع داعها
+
+267
+00:19:39,290 --> 00:19:44,750
+دائري مثبت عليها Anti-IgM مثبت عليها Anti-IgM اللي
+
+268
+00:19:44,750 --> 00:19:47,890
+هو هذا اللون الأزرق فلاقيت أنا بضيف عينة الـ serum
+
+269
+00:19:47,890 --> 00:19:52,610
+إذا كان الـ IgM موجود هيربط مع الـ Anti-IgM بعدين
+
+270
+00:19:52,610 --> 00:19:56,860
+بعمل washing عشان أتخلص من أي إجزة من الـ plasmaأو
+
+271
+00:19:56,860 --> 00:20:02,780
+من الـ Serum تمام الخطوة اللي بعدها بضيف Particles
+
+272
+00:20:02,780 --> 00:20:07,440
+أو Vessels ملونة محمل عليها الـ Antigen هلاقيت الـ
+
+273
+00:20:07,440 --> 00:20:11,680
+Vessels هذه إذا لاقت الـ Antibody الـ IgM موجود
+
+274
+00:20:11,680 --> 00:20:16,680
+هتروحه هي مرتبطة فيه و تظهر على شكل انتشار على قاع
+
+275
+00:20:16,680 --> 00:20:19,620
+الـ Well يعني هتكون الصورة عندي على شكل انتشار
+
+276
+00:20:19,620 --> 00:20:26,130
+شايفين كيف؟ بتكون منتشرة الآنالخيار التاني إنه
+
+277
+00:20:26,130 --> 00:20:29,030
+يكون الـ Serum مافيه Antibody عن العينة Negative
+
+278
+00:20:29,030 --> 00:20:33,930
+إذا كانت العينة Negative مش هيرتبط الـ IgM من الـ
+
+279
+00:20:33,930 --> 00:20:37,550
+Well وبالتالي الحبيبات هذه الـ Vessels الخضراء
+
+280
+00:20:37,550 --> 00:20:41,560
+اللي أنا ضفتهاهتتجمع في القاع بدل من أن تنتشر على
+
+281
+00:20:41,560 --> 00:20:44,820
+جدران الـ Well هتتجمع في القاع لأنها ما لقيت حاجة
+
+282
+00:20:44,820 --> 00:20:49,760
+ترتبط فيها فهتنزل على شكل نقطة في قاع ال tube طبعا
+
+283
+00:20:49,760 --> 00:20:52,500
+اللي بيساعدني أشوف ال agglutination أو التجمع على
+
+284
+00:20:52,500 --> 00:20:56,500
+هذا الشكل إن ال well على شكل U فهذا بيسمح لها إنها
+
+285
+00:20:56,500 --> 00:21:00,460
+ما ارتبطت هتنزل في القاع ويظهر ال reaction بهذا
+
+286
+00:21:00,460 --> 00:21:04,020
+الشكل تجمع في قاع الأنبوبة إذا ال negative تجمع
+
+287
+00:21:04,020 --> 00:21:09,260
+بهذا الشكل ال positive انتشار تمام؟هنا في عندنا
+
+288
+00:21:09,260 --> 00:21:12,060
+ملاحظة حاجة بيسموها الـ Ectric phase الـ Ectric
+
+289
+00:21:12,060 --> 00:21:15,580
+phase هي مرحلة الـ switching ما بين الـ IgM و IgG
+
+290
+00:21:15,580 --> 00:21:19,380
+أحياناً هذه المرحلة بتخدعني بيكونوا التانين فيها
+
+291
+00:21:19,380 --> 00:21:25,600
+with low level نيجي للـ IgA antibodies ممكن الـ
+
+292
+00:21:25,600 --> 00:21:28,900
+IgA antibodies تكون موجودة ونحددها في الـ serum في
+
+293
+00:21:28,900 --> 00:21:32,790
+حالات الـ acute infectionسواء acute أو congenital
+
+294
+00:21:32,790 --> 00:21:36,090
+infection ممكن نحددها بالـ ELISA أو بالتكنيك اللي
+
+295
+00:21:36,090 --> 00:21:38,510
+حكينا عنها قبل بشوية اللي هي immunosorbent
+
+296
+00:21:38,510 --> 00:21:42,350
+agglutination assay بدل ما أثبت عليه الـ Anti-IgM
+
+297
+00:21:42,350 --> 00:21:49,990
+بثبت Anti-IgA الـ IgA بظهر بالـ Serum لما يتكون
+
+298
+00:21:49,990 --> 00:21:53,110
+العين affected يعني لما يوصل ال parasite للعين
+
+299
+00:21:53,110 --> 00:21:56,730
+ويتكون فعلا العين اتأثرت أو موجود ال parasite في
+
+300
+00:21:56,730 --> 00:22:00,830
+العينin a number of newborn with congenital
+
+301
+00:22:00,830 --> 00:22:03,950
+toxoplasmosis and negative IgM antibodies the
+
+302
+00:22:03,950 --> 00:22:06,850
+surgical diagnosis has been established by the
+
+303
+00:22:06,850 --> 00:22:11,210
+presence of IgA and IgM يعني أحيانا الطفل أول ما
+
+304
+00:22:11,210 --> 00:22:15,970
+بنولد لو أنا شاكة أنه عنده تكسو ممكن ال IgM يبقى
+
+305
+00:22:15,970 --> 00:22:20,330
+عنده negative لكن ممكن ألاقي ال IgG positive أو ال
+
+306
+00:22:20,330 --> 00:22:26,790
+IgAIgE Antibody ممكن يتحدد برضه بالـ ELISA في الـ
+
+307
+00:22:26,790 --> 00:22:29,550
+Acutely Infected Adult وفي حالات الـ Congenital
+
+308
+00:22:29,550 --> 00:22:35,790
+Toxoplasmosis ال duration of IgE قليلة كتير أقل من
+
+309
+00:22:35,790 --> 00:22:39,930
+الـ IgM أو الـ IgA يعني ممكن يساعدني في التشخيص ال
+
+310
+00:22:39,930 --> 00:22:42,250
+recent acquired infection لأنه دُغري بينجل بعدين
+
+311
+00:22:42,250 --> 00:22:45,290
+جي للـ histological diagnosis ممكن ال diagnosis
+
+312
+00:22:45,290 --> 00:22:50,560
+نعمل من خلال ال biopsy ناخد ال tissue sectionونشوف
+
+313
+00:22:50,560 --> 00:22:54,180
+الـ Parasite فيه مباشرة ممكن نستخدم
+
+314
+00:22:54,180 --> 00:22:58,460
+Immunofluorescence Stain عشان نشوف ال Parasite
+
+315
+00:22:58,460 --> 00:23:02,400
+ممكن نستخدم Sabine Field Man Stain طبعا هذه
+
+316
+00:23:02,400 --> 00:23:06,000
+التقنية مش كتير يعنى مش روتينية ومتستخدمش كتير
+
+317
+00:23:06,000 --> 00:23:09,340
+لأنه أول إشي العينات هذه صعب أني أحصل عليها يعني
+
+318
+00:23:09,340 --> 00:23:12,300
+أنا بدأ أخد Tissue Biopsy عشان أشخص Toxin لأ يعني
+
+319
+00:23:12,300 --> 00:23:16,380
+حاجة مش عملية بالمرة تفضل يقول ممكن بغرض الأبحاث
+
+320
+00:23:16,380 --> 00:23:19,930
+أنها تنعمل أو تنعمل لل Animals مثلاأما للـ human
+
+321
+00:23:19,930 --> 00:23:24,810
+عادة ما يعني مش حاجة روتينية لل isolation برضه هذه
+
+322
+00:23:24,810 --> 00:23:30,530
+طريقة يعني مش مابتنعملش كتير و مش روتينية أنه أخد
+
+323
+00:23:30,530 --> 00:23:34,450
+ال parasite و أعمله isolation من ال blood أو من أي
+
+324
+00:23:34,450 --> 00:23:38,530
+body fluid و أعمله culture أو أعمله animal
+
+325
+00:23:38,530 --> 00:23:41,350
+inoculation و أشوف النتيجة بتاعته بس طبعا زي ما
+
+326
+00:23:41,350 --> 00:23:47,080
+قلتلكم هي مكلفة و بتغلب و بتاخد وقت طويلالـ PCR
+
+327
+00:23:47,080 --> 00:23:51,800
+إنه نشوف الـ DNA للفيروس للـ Parasite وهذا من
+
+328
+00:23:51,800 --> 00:23:55,960
+الفحصات اللي بتنعمل على الـ amniotic fluid طبعا
+
+329
+00:23:55,960 --> 00:24:02,060
+إذا كانت الأم يعني ظهر عند ال baby هذا دلائل تشوه
+
+330
+00:24:02,060 --> 00:24:06,940
+مثلا أو فيه خطورة على ال baby معينة فيه أعراض تقصه
+
+331
+00:24:06,940 --> 00:24:09,880
+يعني الدكتور كتير مرجح إنه يكون فيه تقصه Plasmosis
+
+332
+00:24:09,880 --> 00:24:13,400
+وفحصات الـ serology لا قادرة تثبت ولا قادرة تنفي
+
+333
+00:24:13,400 --> 00:24:16,990
+إنه فيه فعلا infection ولا لأممكن ياخدوا عينة
+
+334
+00:24:16,990 --> 00:24:20,090
+Amniotic Flu ويعملوا لها PCR عشان يشوفوا الـ DNA
+
+335
+00:24:20,090 --> 00:24:25,390
+للطفال ممكن ياخدوا Fetal Blood Sampling ياخدوا
+
+336
+00:24:25,390 --> 00:24:28,850
+عينة blood من الـ umbilical cord الفيتس خلال الحمل
+
+337
+00:24:28,850 --> 00:24:33,870
+بس هاد الطريقة يعني invasive وممكن تشكل risk على
+
+338
+00:24:33,870 --> 00:24:36,390
+ال baby يعني ممكن هي نفسها تكون خطيرة على ال baby
+
+339
+00:24:37,150 --> 00:24:40,370
+عشان هيك يعني كانت زمان تستخدم في شكل أساسي بس
+
+340
+00:24:40,370 --> 00:24:44,830
+الآن ماتستخدمش لأنها الـ Ocular Disease إنه كيف
+
+341
+00:24:44,830 --> 00:24:47,390
+بدنا نحدد إذا كان فيه مشكلة في العين ولا لأ طبعا
+
+342
+00:24:47,390 --> 00:24:51,130
+هذه بتبين إن الطبيب العيون بيشوف ال lesion في
+
+343
+00:24:51,130 --> 00:24:55,830
+العين بالإضافة لـ Serological Testing قياس ال
+
+344
+00:24:55,830 --> 00:24:57,430
+level الخاصة لل IGA
+
+345
+00:25:00,320 --> 00:25:03,700
+نيجي للـ Chlamydia الـ Chlamydia برضه من الأشياء
+
+346
+00:25:03,700 --> 00:25:06,320
+اللي ممكن أو من البراسايت اللي ممكن تأذي الأم
+
+347
+00:25:06,320 --> 00:25:09,780
+الحامل وتسبب Abortion هي عبارة عن Obligate
+
+348
+00:25:09,780 --> 00:25:13,680
+Intracellular Parasite في منها أكتر من نوع في منها
+
+349
+00:25:13,680 --> 00:25:18,020
+Chlamydia Cetaceae وفي منها Lymphogranulomatous
+
+350
+00:25:18,020 --> 00:25:24,060
+وفي منها Trachomatous وفي Oculogenitis نيجي لأول
+
+351
+00:25:24,060 --> 00:25:29,370
+نوع اللي هو Cetacosis عبارة عنال respiratory
+
+352
+00:25:29,370 --> 00:25:33,450
+disease بيجي من ال infected birds ال infected
+
+353
+00:25:33,450 --> 00:25:37,670
+birds بتطلع لكلاميديا سيتاسي في ال stool و ممكن عن
+
+354
+00:25:37,670 --> 00:25:43,150
+طريق الغبار ينتقل إلى الإنسان طبعا بسبب infection
+
+355
+00:25:43,150 --> 00:25:46,430
+في ال upper respiratory system و ممكن يؤدي إلى
+
+356
+00:25:46,430 --> 00:25:50,250
+نمونيا كيف بنعمل ال diagnosis طبعا حسب مكان العينة
+
+357
+00:25:50,250 --> 00:25:54,330
+هناخد sputum و ممكن نعمل blood testSmear to show
+
+358
+00:25:54,330 --> 00:25:57,530
+elementary bodies الـ elementary bodies هذه بتبين
+
+359
+00:25:57,530 --> 00:26:00,190
+في داخل الخلاهي الكلاميديا نفسها بتبين في داخل
+
+360
+00:26:00,190 --> 00:26:02,650
+الخلايا اللي لها شكل معين بيسمى بالـ elementary
+
+361
+00:26:02,650 --> 00:26:10,070
+bodies ممكن نعمل إليزا و ممكن نعمل PCR ممكن
+
+362
+00:26:10,070 --> 00:26:14,490
+نعمل لها isolation في اليكساك اللي هو ال
+
+363
+00:26:14,490 --> 00:26:19,970
+embryonated egg or intracerebral or intranasal في
+
+364
+00:26:19,970 --> 00:26:22,770
+المايس يعني ممكن نعمل animal oligulation أو egg
+
+365
+00:26:23,080 --> 00:26:25,440
+inoculation من الـ serological tests اللي ممكن
+
+366
+00:26:25,440 --> 00:26:28,500
+تنعمل complement fixation agglutination ال
+
+367
+00:26:28,500 --> 00:26:31,060
+neutralization هدول هناخدهم ال agglutination اللي
+
+368
+00:26:31,060 --> 00:26:32,620
+بنعرفه و ال complement fixation و ال
+
+369
+00:26:32,620 --> 00:26:36,700
+neutralization هناخدهم لقدام شاء الله ال
+
+370
+00:26:36,700 --> 00:26:39,900
+lymphogranuloma venerum عبارة عن venereal disease
+
+371
+00:26:39,900 --> 00:26:44,300
+بيأثر على ال lymph nodes بيعمل enlargement في ال
+
+372
+00:26:44,300 --> 00:26:47,700
+lymph nodes بالإضافة لإنه ممكن يعمل infection ل
+
+373
+00:26:47,700 --> 00:26:53,190
+اليوريثرة و طبعا يعني بيصاحبه systemic symptomsالـ
+
+374
+00:26:53,190 --> 00:26:55,810
+Lab diagnosis ممكن نعمل سمير عشان نشوف الـ
+
+375
+00:26:55,810 --> 00:26:58,750
+elementary body ممكن ناخد بيبس من الـ infected
+
+376
+00:26:58,750 --> 00:27:02,350
+lymph node برضه الـ bust cells اللي فيها ممكن يكون
+
+377
+00:27:02,350 --> 00:27:06,930
+فيها الـ elementary bodies الكلتر ما بتفيدني لأن
+
+378
+00:27:06,930 --> 00:27:09,810
+هي عبارة عن intracellular parasite فبالتالي لو
+
+379
+00:27:09,810 --> 00:27:14,590
+عملت كلتر هتبقى إقليمية Trachomatous طبعا هذه ممكن
+
+380
+00:27:14,590 --> 00:27:19,530
+تسبب conjunctivitis وهي عبارة عن sexually
+
+381
+00:27:19,530 --> 00:27:23,600
+transmitted diseaseهي ممكن تسبب تركومة عن طريق
+
+382
+00:27:23,600 --> 00:27:27,600
+نموها في الـ conjunctiva و القرنية للـ I يعني
+
+383
+00:27:27,600 --> 00:27:33,260
+بتنمو في أنسجة العين و بتسبب keratoconjunctivitis
+
+384
+00:27:33,260 --> 00:27:36,640
+بتسبب التهاب للعين كيف ممكن تنتقل للطفل خلال
+
+385
+00:27:36,640 --> 00:27:39,800
+الولادة عبر مرور الطفل في ال birth canal ممكن
+
+386
+00:27:39,800 --> 00:27:42,880
+تتأثر على الطفل و تعمل عنده مضاعفات زي ال
+
+387
+00:27:42,880 --> 00:27:46,640
+conjunctivitis و ممكن تعمل عنده كمان التهاب في
+
+388
+00:27:46,640 --> 00:27:48,480
+الرئتين اللي هو يومانيا
+
+389
+00:27:51,800 --> 00:27:56,920
+هنا بقولك إنه كتير في ستات بيصابوا فيها بس مايبقوا
+
+390
+00:27:56,920 --> 00:28:01,120
+عندهم أي أعراض لكن هذه مشكلتها إن لو ما اتعالجت
+
+391
+00:28:01,120 --> 00:28:04,920
+ممكن تعمل damage في ال reproductive system عند ال
+
+392
+00:28:04,920 --> 00:28:09,320
+female خاصة عند الفلوبيا نتيوب ممكن تعمل
+
+393
+00:28:09,320 --> 00:28:13,500
+infertility نتيجة تسديد الفلوبيا نتيوب ممكن تعمل
+
+394
+00:28:13,500 --> 00:28:18,240
+tubular pregnancy يعني تعمل حمل خارج الرحم اللي هو
+
+395
+00:28:18,240 --> 00:28:22,130
+في قناة فلوب وطبعا هذا بيكون كتير سيءالـ Lab
+
+396
+00:28:22,130 --> 00:28:25,190
+diagnosis ممكن نعمل I-swab عشان برضه نشوف الـ
+
+397
+00:28:25,190 --> 00:28:26,910
+elementary .. إيش هي الـ elementary bodies؟ قاعدين
+
+398
+00:28:26,910 --> 00:28:30,470
+إحنا بنقولها الـ elementary bodies هي لما بيجي
+
+399
+00:28:30,470 --> 00:28:34,610
+ميكروب مثلا زي الـChlamydia وبيجي الفاجوسايت تعمله
+
+400
+00:28:34,610 --> 00:28:40,210
+Fagocytosis هيظهر في داخل الخلية على شكل حبيبات
+
+401
+00:28:40,210 --> 00:28:44,890
+هذه هي يعني هذه الحبيبات اللي ظهر في داخل الخلية
+
+402
+00:28:45,960 --> 00:28:49,660
+ممكن نعمل الـ ELISA نشوف الـ IgM أو IgG أو IgE
+
+403
+00:28:49,660 --> 00:28:52,580
+نيجي للروبيلا الروبيلا اللى بتسمى كانت قديما
+
+404
+00:28:52,580 --> 00:28:58,240
+بالحصبة الألمانية عبارة عن mild disease بينتقل عن
+
+405
+00:28:58,240 --> 00:29:02,700
+طريق الجهاز التنفسى أو skin contact أو عن طريق الـ
+
+406
+00:29:02,700 --> 00:29:06,700
+congenital يعني من الطفل ينتقل من الأم إلى طفلها
+
+407
+00:29:07,370 --> 00:29:11,190
+The virus can cross placental wall and infect the
+
+408
+00:29:11,190 --> 00:29:13,830
+fetus يعني هي مشكلته أنه ممكن يعدي لـ placenta
+
+409
+00:29:13,830 --> 00:29:17,750
+ويصيب الطفل this may lead to fetal death or
+
+410
+00:29:17,750 --> 00:29:21,670
+congenital defect يعني ممكن يؤدي إلى وفاة الطفل
+
+411
+00:29:21,670 --> 00:29:26,190
+وممكن يؤدي إلى birth defect من الحاجات اللي ممكن
+
+412
+00:29:26,190 --> 00:29:31,150
+تأثر أو تأديها لـ Bruxelles الـ hearing loss فقدان
+
+413
+00:29:31,150 --> 00:29:34,750
+السماعة تخلف عقلي mental retardation heart disease
+
+414
+00:29:35,540 --> 00:29:39,020
+retarded growth أثر على نمو الطفل blood disorders
+
+415
+00:29:39,020 --> 00:29:42,600
+vision problems مشاكل في الرؤية pneumonia عشان هيك
+
+416
+00:29:42,600 --> 00:29:47,560
+هذه من الأشياء اللي بيتطعموا إليها الأطفال الصغار
+
+417
+00:29:47,560 --> 00:29:52,880
+وحتى ال female بيعاد ينعطق جرعة داعمة في سن تقريبا
+
+418
+00:29:52,880 --> 00:29:57,200
+12 أو 13 سنة عشان يضمنوا إن ال title لل antibodies
+
+419
+00:29:57,200 --> 00:30:01,860
+لإلها موجود بشكل محترم وإنه مايأثر لو صار حمل بعد
+
+420
+00:30:01,860 --> 00:30:09,170
+هيك في المستقبل مايأثر على الأجنةفي عند الستات ال
+
+421
+00:30:09,170 --> 00:30:11,610
+lab diagnosis فيها فحوصات زي ال complement
+
+422
+00:30:11,610 --> 00:30:14,630
+fixation ال neutralization ال hemagglutination
+
+423
+00:30:14,630 --> 00:30:20,390
+inhibition ال إيليزا IGM and IGG طبعا هذه هي
+
+424
+00:30:20,390 --> 00:30:23,890
+الفحوصات هدول التانين احنا لسه هناخدهم لقدام ال
+
+425
+00:30:23,890 --> 00:30:26,910
+principle لإلهم اللي هو ال complement fixation و
+
+426
+00:30:26,910 --> 00:30:30,050
+ال neutralization ال hemagglutination inhibition
+
+427
+00:30:30,050 --> 00:30:34,650
+هذا إذا تدل على شاء بتدل على أنهالروبيلا بتعمل
+
+428
+00:30:34,650 --> 00:30:37,170
+hemagglutination لأنه مش احنا قولنا في بعض ال
+
+429
+00:30:37,170 --> 00:30:41,090
+viruses بتعمل hemagglutination فأنا لما بكون أدور
+
+430
+00:30:41,090 --> 00:30:45,090
+على ال serum لإلها ال antibody في ال serum إذا كان
+
+431
+00:30:45,090 --> 00:30:49,570
+موجود هيعمل hemagglutination inhibition تمام ممكن
+
+432
+00:30:49,570 --> 00:30:56,190
+نعمل إليزا IgM أو IgG الآن نحكي عن ال herpes virus
+
+433
+00:30:56,190 --> 00:31:00,690
+ال herpes في منه خمس أنواع الخمس أنواع one two
+
+434
+00:31:00,690 --> 00:31:05,320
+three four fiveخلّيني أشوف كل واحدة سمبل بسيطة عنه
+
+435
+00:31:05,320 --> 00:31:08,980
+«Virus 1» اللي هي بيسبب الحبيبات اللي بتظهر على
+
+436
+00:31:08,980 --> 00:31:14,020
+الشفتان بعد الحمّة بيسموه «fever blisters» هذا
+
+437
+00:31:14,020 --> 00:31:18,300
+عادة يعني بيكون موجود، latent، خامل، بعد أول مرة
+
+438
+00:31:18,300 --> 00:31:22,810
+بيصاب فيه الإنسانبمجرد ما تضعف المناعة نتيجة حمى
+
+439
+00:31:22,810 --> 00:31:26,210
+نتيجة نزلة برد بتلاقي بعاوض برجع يعني كل ما
+
+440
+00:31:26,210 --> 00:31:29,390
+الإنسان ضعفت مناعته بنشط هذا الفيروس و بعمل الحب
+
+441
+00:31:29,390 --> 00:31:33,050
+اللي ممكن تصيبنا كلنا بعد نزلات البرد نيجي لل
+
+442
+00:31:33,050 --> 00:31:36,970
+Herpes Simplex Virus 2 هذا عبارة عن sexually
+
+443
+00:31:36,970 --> 00:31:40,730
+transmitted disease بعمل blisters في منطقة
+
+444
+00:31:40,730 --> 00:31:45,650
+الجينيتالية نيجي
+
+445
+00:31:45,650 --> 00:31:49,190
+لل Herpes Simplex Virus اللي هو type 3الـ Type 3
+
+446
+00:31:49,190 --> 00:31:52,650
+هذا اللي هو عبارة عن الـ Varicose Loss Virus هذا
+
+447
+00:31:52,650 --> 00:31:57,110
+اللي بيسبب الـ Chickenpox اللي وجده للأطفال طبعا
+
+448
+00:31:57,110 --> 00:32:00,310
+هذا ممكن يصيب الأطفال أو يصيب الأكبار إذا أصاب
+
+449
+00:32:00,310 --> 00:32:03,210
+الأكبار غالبا بيجيهم على شكل ما يسمى بالحزام
+
+450
+00:32:03,210 --> 00:32:06,490
+الناري وبتبقى أعراضه شديدة على الأكبار مختلفة عن
+
+451
+00:32:06,490 --> 00:32:09,330
+الأصغار الأصغار بيكون بسيطة حمى يومين مع شوية
+
+452
+00:32:09,330 --> 00:32:12,890
+حبيبته وبينتهي بس مع الأكبار يعني بياخد وقت أطول
+
+453
+00:32:12,890 --> 00:32:20,310
+لغاية ما يطيببنتقل عن طريق العطس أو السعال من
+
+454
+00:32:20,310 --> 00:32:25,410
+الإنسان المريض إلى الإنسان السليماني طبعاً هذا
+
+455
+00:32:25,410 --> 00:32:29,590
+بشكل خطورة فعلية لو أصيبت فيه السد الحامل ممكن
+
+456
+00:32:29,590 --> 00:32:33,190
+يعمل abortion وممكن يعمل scarring لل baby ممكن
+
+457
+00:32:33,190 --> 00:32:36,070
+يعمل mal formation في ال limbs، في الأطراف، تشوّه
+
+458
+00:32:36,070 --> 00:32:41,610
+في الأطراف ممكن يعمل مشاكل في العين وفي الدماغ
+
+459
+00:32:41,610 --> 00:32:45,530
+نيجي لل diagnosis of herpes simplex virusأول حاجة
+
+460
+00:32:45,530 --> 00:32:48,310
+الـ Viral Culture بس طبعا احنا بندور على بدائي لأن
+
+461
+00:32:48,310 --> 00:32:52,830
+هذا الحل يعني مش سهل و بكلف و بياخد وقت في عندي
+
+462
+00:32:52,830 --> 00:32:56,150
+الـ Zinc Smear Zinc Smear هي عبارة عن كشطة بتتاخد
+
+463
+00:32:56,150 --> 00:33:01,310
+من مكان الحبيبات اللي طالع نتيجة الفيروس و بتنصبغ
+
+464
+00:33:01,310 --> 00:33:04,530
+تظهر فيها حاجة تسمى Zinc Cell اللي لها criteria
+
+465
+00:33:04,530 --> 00:33:09,310
+خاصة إذا طبعا اتوفر عندي Monoclonal Antibody ممكن
+
+466
+00:33:09,310 --> 00:33:12,950
+أعمل Direct Immunofluorescence Study ممكن نعمل PCR
+
+467
+00:33:13,540 --> 00:33:18,000
+ممكن نعمل type specific surgical test لـ Herpes
+
+468
+00:33:18,000 --> 00:33:20,840
+simplex virus نيجي للـ cytomegalovirus الـ
+
+469
+00:33:20,840 --> 00:33:23,500
+cytomegalovirus بيسمى بالـ salivary gland virus
+
+470
+00:33:23,500 --> 00:33:26,260
+which may be infect salivary glands or parotid
+
+471
+00:33:26,260 --> 00:33:30,800
+gland نيجي
+
+472
+00:33:30,800 --> 00:33:36,720
+للـ symptoms of cytomegalovirus تقريبا 90% من
+
+473
+00:33:36,720 --> 00:33:39,180
+الحالات الـ congenital مايبقاش عندهم أعراض عند
+
+474
+00:33:39,180 --> 00:33:46,400
+الولادة لكن منهمتقريبًا لغاية 15% بيعانوا من أهراض
+
+475
+00:33:46,400 --> 00:33:49,960
+في السنة الأولى زي «psychomotor» حاجات إلها علاقة
+
+476
+00:33:49,960 --> 00:33:54,080
+بالحركة «hearing» «neurologic» «ocular» «dental
+
+477
+00:33:54,080 --> 00:33:57,120
+abnormalities» with the first few years of life
+
+478
+00:33:57,120 --> 00:34:01,240
+«microcephaly» «Caesars» «pitagia» برضه ممكن إنها
+
+479
+00:34:01,240 --> 00:34:03,780
+اتبين يعني ممكن كل الأشياء هذه تظهر عندهم في
+
+480
+00:34:03,780 --> 00:34:10,910
+السنوات الأولى من العمر10% من الحالات بتطور سنسو
+
+481
+00:34:10,910 --> 00:34:15,790
+neural hearing loss يعني فقدان للسمع حاجة إلها
+
+482
+00:34:15,790 --> 00:34:19,910
+علاقة بالعصب السمعي يعني تأثر للعصب السمعي هو بتلف
+
+483
+00:34:19,910 --> 00:34:23,490
+بأثر على السمعي ‏easy لل lab diagnosis ممكن ناخد
+
+484
+00:34:23,490 --> 00:34:29,330
+pathological studiesإذا أنا أخدت tissue section
+
+485
+00:34:29,330 --> 00:34:34,210
+يعني بلاقي فيه الخلايا المصابة بعض ال particles أو
+
+486
+00:34:34,210 --> 00:34:38,690
+ال inclusions الخاصة بالفيروس واضحة ممكن بالفيروس
+
+487
+00:34:38,690 --> 00:34:45,130
+isolation أو نعمل إليزا IGG أو IGN هنا بقولك ال
+
+488
+00:34:45,130 --> 00:34:48,890
+IGG لما بعمله نادر لما بطلع نيجاتيب فإذا طلع معايا
+
+489
+00:34:48,890 --> 00:34:52,130
+positive لازم أعيده بعد أسبوعين أو تلت أسابيع إذا
+
+490
+00:34:52,130 --> 00:34:55,510
+لقيت ال titer زي ما هو فاعتبر العينة نيجاتيةإذا
+
+491
+00:34:55,510 --> 00:34:59,410
+رأيت فار ارتفاع في الـ tighter مع الكلام إن العينة
+
+492
+00:34:59,410 --> 00:35:02,750
+positive هيك بنكون مرنة على ال torch
+
diff --git a/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/rTh-VWmrZ78_raw.srt b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/rTh-VWmrZ78_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..15a1b4193404ae02e13b4af9b37461e8bc988650
--- /dev/null
+++ b/PL9fwy3NUQKwbgCDEXeWKjhA8JkBZGSYYJ/rTh-VWmrZ78_raw.srt
@@ -0,0 +1,1968 @@
+1
+00:00:01,400 --> 00:00:06,740
+بسم الله الرحمن الرحيم موضوع هذه المحاضرة يتكلم عن
+
+2
+00:00:06,740 --> 00:00:11,680
+مجموعة من الـ organism التي تسبب الـ abortion
+
+3
+00:00:11,680 --> 00:00:19,900
+اختصرت في torch torch هي اختصار لـ toxoplasmosis
+
+4
+00:00:19,900 --> 00:00:27,360
+others, rubella, cytomegalovirus, herbs هذه بعض ال
+
+5
+00:00:27,360 --> 00:00:31,730
+organisms التي تسبب الـ abortionThe five
+
+6
+00:00:31,730 --> 00:00:34,870
+categories of organisms whose antibodies are
+
+7
+00:00:34,870 --> 00:00:38,030
+measured by the torch test are grouped together
+
+8
+00:00:38,030 --> 00:00:41,250
+because they can cause abortion for pregnant women
+
+9
+00:00:41,250 --> 00:00:45,750
+and or birth defects in newborn يعني هذه المجموعة
+
+10
+00:00:45,750 --> 00:00:51,510
+من الفحوصات أو هذه المجموعة من الـ organisms بنحدد
+
+11
+00:00:51,510 --> 00:00:55,750
+الـ antibodies لإلها غالبا بتنطلب مع بعض لما يصير
+
+12
+00:00:55,750 --> 00:01:02,150
+recurrent abortion أو يصير فيbirth defect يعني
+
+13
+00:01:02,150 --> 00:01:06,550
+يبقى الستة هذه مثلا أنجبات مرة أو تنتين والأطفال
+
+14
+00:01:06,550 --> 00:01:10,110
+ييجوا عندهم تشوه أو عيب خلقي فممكن تنطلب هذه
+
+15
+00:01:10,110 --> 00:01:14,230
+الفحوصات عشان نتأكد من عدم وجود أي واحد منهم يعني
+
+16
+00:01:14,230 --> 00:01:17,850
+هذه الأشياء ممكن تسبب abortion وفي بعض الأحيان لو
+
+17
+00:01:17,850 --> 00:01:24,250
+ما صار abortion وكمل الحمل بيتمل مع تشوه خلقي أول
+
+18
+00:01:24,250 --> 00:01:28,490
+واحد له تكسب Lasmosis ثاني واحد others بيشمل
+
+19
+00:01:29,050 --> 00:01:32,990
+Chlamydia, Syphilis, Hepatitis B, Coxsackievirus,
+
+20
+00:01:33,130 --> 00:01:37,490
+Ibstambar virus, Varicella-zoster virus and Human
+
+21
+00:01:37,490 --> 00:01:44,170
+Box virus الـR روبيلة, Cytomegalovirus الـC, Herbs
+
+22
+00:01:44,170 --> 00:01:45,290
+الـH
+
+23
+00:01:51,320 --> 00:01:55,640
+طبعاً هناك مجموعة كبيرة من أسباب الـ abortion يعني
+
+24
+00:01:55,640 --> 00:01:59,820
+فيه أشياء ما إلها علاقة أصلا بالـ organisms وفيه
+
+25
+00:01:59,820 --> 00:02:04,100
+أشياء إلها علاقة بالـ organisms الأشياء اللي إلها
+
+26
+00:02:04,100 --> 00:02:08,040
+علاقة بالـ organisms هي قد تكون viral أو non-viral
+
+27
+00:02:08,040 --> 00:02:12,040
+بعض الـ viruses اللي ممكن تسبب الـ abortion زي الـ
+
+28
+00:02:12,040 --> 00:02:17,320
+cytomegalovirus روبيلا، herpes، الـ non-virus زي
+
+29
+00:02:17,320 --> 00:02:21,180
+الكلاميديا والتكسوفالـ Plasma Gondii التوكسو
+
+30
+00:02:21,180 --> 00:02:25,040
+بلازما هذه عبارة عن براسايت لكلاميديا هي غالبا
+
+31
+00:02:25,040 --> 00:02:31,360
+بكتيريا عندها بعض الصفات من الفيروس نيجي
+
+32
+00:02:31,360 --> 00:02:35,740
+بداية للـ Toxoplasmosis التوكسو بلازموزز عبارة عن
+
+33
+00:02:35,740 --> 00:02:42,200
+مرض يسببه طفل اللي هو التوكسو بلازما Gondii يعتبر
+
+34
+00:02:42,200 --> 00:02:46,080
+zoonotic disease اش يعني zoonotic disease؟
+
+35
+00:02:46,080 --> 00:02:50,220
+zoonotic diseaseتعني بإن هذا المرض ينتقل من
+
+36
+00:02:50,220 --> 00:02:54,540
+الحيوان إلى الإنسان ويسبب له الأمراض Caused by
+
+37
+00:02:54,540 --> 00:02:58,700
+infection with a protozoa Toxoplasma gondii
+
+38
+00:02:58,700 --> 00:03:03,960
+Toxoplasmosis في البداية ممكن يسبب Flu-like
+
+39
+00:03:03,960 --> 00:03:08,740
+symptoms يعني ممكن يسبب أعراض خفيفة زي أعراض الـ
+
+40
+00:03:08,740 --> 00:03:14,340
+Influenza عند بعض الناس ناس أخرى يعني ممكن يجيهم
+
+41
+00:03:14,340 --> 00:03:20,160
+هذا الطفلبدون ما يسبب عندهم أي أعراض يعني بيجي
+
+42
+00:03:20,160 --> 00:03:24,980
+وبيخلص بدون ما يسبب عندهم أي symptoms for infants
+
+43
+00:03:24,980 --> 00:03:27,980
+born to infected mother and for people with
+
+44
+00:03:27,980 --> 00:03:31,640
+weakened immune system toxoplasmosis can cause
+
+45
+00:03:31,640 --> 00:03:35,720
+extremely serious complications وين بتكمل المشكلة
+
+46
+00:03:35,720 --> 00:03:42,760
+لو كان أصيبت ست حامل بهذا الطفل أو أصيب فيه إنسان
+
+47
+00:03:42,760 --> 00:03:47,030
+من ذوي المناعة المنخفضةهنا ممكن يعمل عندنا serious
+
+48
+00:03:47,030 --> 00:03:52,030
+complications ممكن يعمل عندنا أعراض ومضاعفات خطيرة
+
+49
+00:03:52,030 --> 00:03:55,430
+أول
+
+50
+00:03:55,430 --> 00:03:59,910
+حاجة نحكي على الـ Toxoplasma Gondii الـ Toxoplasma
+
+51
+00:03:59,910 --> 00:04:03,490
+Gondii عبارة عن obligate intracellular parasite
+
+52
+00:04:03,490 --> 00:04:10,230
+بعيش في داخل الخلية طبعا هذا الطفل عنده القدرة على
+
+53
+00:04:10,230 --> 00:04:14,740
+أنه يصيب كلالـ warm-blooded animals اللي هي كل
+
+54
+00:04:14,740 --> 00:04:17,540
+الحيوانات ذوات الدم الحار يعني lack of host
+
+55
+00:04:17,540 --> 00:04:22,920
+specificity مالهاش host محدد تعتبر ال cats هي ال
+
+56
+00:04:22,920 --> 00:04:25,900
+definitive host إيش يعني definitive host؟ يعني
+
+57
+00:04:25,900 --> 00:04:30,700
+بيعتبروا ال host النهائي اللي بيكمل نضوج ال
+
+58
+00:04:30,700 --> 00:04:35,960
+parasite فيه أو الطفال فيه وبيقدر في هذه المرحلة
+
+59
+00:04:35,960 --> 00:04:39,600
+أنه يعمل reproductionفبالتالي في ال «cats» هو
+
+60
+00:04:39,600 --> 00:04:43,060
+بيتكاثر يعني هو ممكن يصيب الحيوانات الأخرى لكن لا
+
+61
+00:04:43,060 --> 00:04:48,240
+يتكاثر فيها هو ينتقل إلها و بتكون كوسيط للنقل مثلا
+
+62
+00:04:48,240 --> 00:04:53,240
+أو مثلا ممكن ينتقل للأبقار ع سبيل المثال لو انتقل
+
+63
+00:04:53,240 --> 00:04:56,880
+للأبقار ممكن ينتقل إلى الإنسان ويصيبه يعمل عنده
+
+64
+00:04:56,880 --> 00:05:02,200
+مشاكل لكن عملية التكاثر بتكون في ال «cat» عشان هيك
+
+65
+00:05:02,200 --> 00:05:07,270
+بيسموها جرثومة خاصة بالقطط و بتسبب الإجهاضTissue
+
+66
+00:05:07,270 --> 00:05:10,330
+cyst formed in any organ especially brain, eyes
+
+67
+00:05:10,330 --> 00:05:13,950
+and strength muscles هذه لو انتقلت إلى الكائن الحي
+
+68
+00:05:13,950 --> 00:05:18,490
+الإنسان أو الحيوان اللي هي الـ cyst بتعيش في
+
+69
+00:05:18,490 --> 00:05:23,750
+الانسشة ممكن في الـbrain، في العين، في ال strength
+
+70
+00:05:23,750 --> 00:05:28,170
+muscles، في العضلات، في أي مكان من الجسم ممكن تعيش
+
+71
+00:05:28,170 --> 00:05:31,890
+وتستقر وتعمل مضاعفات ومشايا هذا الطفل زي ما قلت
+
+72
+00:05:31,890 --> 00:05:35,370
+لكم بيعيش في ال intestine لل cat وهناك بتم تكاثره
+
+73
+00:05:35,860 --> 00:05:39,660
+بطلع الطور المعدى الطور المعدى اللي هو الـ Oocyste
+
+74
+00:05:39,660 --> 00:05:44,360
+الـ Oocyste هذا قد يصيب الأم الحامل مباشرة عن طريق
+
+75
+00:05:44,360 --> 00:05:50,460
+تلوث الطعام بيه الـ Fecal Cat طبعا إذا أصاب الأم
+
+76
+00:05:50,460 --> 00:05:54,480
+الحامل هيعمل مضاعفات عند الجنين قد يصيب مثلا
+
+77
+00:05:54,480 --> 00:06:00,750
+الفئرانوممكن ترجع من تاني إلى القطط قد تصيب
+
+78
+00:06:00,750 --> 00:06:04,230
+الحيوانات الأخرى اللي الإنسان بيتغذى عليها زي
+
+79
+00:06:04,230 --> 00:06:09,530
+الأبطار والأغنام إذا أصاب هذه الحيوانات ممكن تنتقل
+
+80
+00:06:09,530 --> 00:06:14,130
+من هذه الحيوانات عبر التعامل مع اللحوم الغير مطهوة
+
+81
+00:06:14,130 --> 00:06:18,410
+جيدا وتنتقل إلى الإنسان يعني قد تنتقل مباشرة الـ
+
+82
+00:06:18,410 --> 00:06:22,390
+Oocyte إلى الإنسان أو قد تنتقل عبر وسيط من
+
+83
+00:06:22,390 --> 00:06:27,010
+الحيوانات تدخل هذه لجسم الحيوانوتستقر في ال
+
+84
+00:06:27,010 --> 00:06:31,530
+muscles بتاعته وبعد هيك تنتقل لإنسان أخذ هذه
+
+85
+00:06:31,530 --> 00:06:37,110
+العضلات الغير مطهوة جيدا أو اللحم نيجي لطرق انتقال
+
+86
+00:06:37,110 --> 00:06:42,750
+العدوى كيف تنتقل العدوى إلى الإنسان أول حاجة ممكن
+
+87
+00:06:42,750 --> 00:06:48,150
+تنتقل من اللحم الغير مطهو جيدا يعني لو اللحمة مثلا
+
+88
+00:06:48,150 --> 00:06:52,520
+ماكنتش متعرضة لدرجة حرارة مناسبةأو مشتقات اللحوم
+
+89
+00:06:52,520 --> 00:06:57,880
+زي الـ Luncheon والسجق والبرجر هذه الأشياء لو ما
+
+90
+00:06:57,880 --> 00:07:02,820
+كانت مطهوة بالشكل الجيد ممكن تؤدي إلى نقل الطفل
+
+91
+00:07:02,820 --> 00:07:07,960
+شغلة تانية لو أنا اللحوم الغير مطهوة عند التعامل
+
+92
+00:07:07,960 --> 00:07:12,560
+معها وتقطيعها وغسلها الأدوات اللي حطيتها فيها
+
+93
+00:07:12,560 --> 00:07:16,390
+ماكنتش منضفاها كويس زيالـ cutting board مثلًا لوحة
+
+94
+00:07:16,390 --> 00:07:20,450
+التقطيع هذه ممكن يعلق فيها هذا الطفيل وبعد هيك
+
+95
+00:07:20,450 --> 00:07:25,270
+ينتقل إلى الخضار والاشياء اللي بتأكل fresh ما
+
+96
+00:07:25,270 --> 00:07:28,090
+بتنطبخ فبالتالي ممكن تصير الإصابة ك cross
+
+97
+00:07:28,090 --> 00:07:31,470
+-contamination drinking water contaminated with
+
+98
+00:07:31,470 --> 00:07:35,950
+toxoplasma gondii لو الإنسان شرب ميه ملوثة بهذا
+
+99
+00:07:35,950 --> 00:07:40,730
+الطفيل ممكن يصاب بالعدل mother to childcongenital
+
+100
+00:07:40,730 --> 00:07:45,570
+transmission ممكن ينتقل برضه من الأم إلى الطفل إذا
+
+101
+00:07:45,570 --> 00:07:49,070
+كانت مثلا الأم مربي بساس والبساس هدول انتقلت
+
+102
+00:07:49,070 --> 00:07:52,890
+العدوى من القطة إلى الأم وممكن تنتقل إلى الطفل
+
+103
+00:07:52,890 --> 00:07:55,670
+accidentally swallowing the parasite through
+
+104
+00:07:55,670 --> 00:07:59,570
+contact with cat feces that contain toxoplasma
+
+105
+00:07:59,570 --> 00:08:03,270
+تمام؟ receiving an infected organ transplant or
+
+106
+00:08:03,270 --> 00:08:08,000
+infected blood via transfusionبس يعني على الرغم إن
+
+107
+00:08:08,000 --> 00:08:11,480
+ممكن تصير هذه الشغلة لكن نادرة من خلال نقل أعضاء
+
+108
+00:08:11,480 --> 00:08:19,080
+أو نقل دم طيب
+
+109
+00:08:19,080 --> 00:08:22,580
+الآن السؤال اللي بيترح نفسه is toxoplasmosis
+
+110
+00:08:22,580 --> 00:08:28,120
+serious عادة toxoplasmosis يعني ما بيخوف ليش؟ لأن
+
+111
+00:08:28,120 --> 00:08:31,120
+ال immune system عنده القدرة على إنه يتعامل معاه
+
+112
+00:08:31,120 --> 00:08:36,370
+ويقضي على ال infection بدون أن يحدث مضاعفاتعادة
+
+113
+00:08:36,370 --> 00:08:40,250
+بعد ال infection معظم الناس بيظل عندهم مناعة ال
+
+114
+00:08:40,250 --> 00:08:45,250
+IGG بتظل عندهم for the rest of life طول حياتهم
+
+115
+00:08:45,250 --> 00:08:49,650
+بيظل ال IGG موجود لكن في بعض الأحيان ممكن يكون
+
+116
+00:08:49,650 --> 00:08:53,290
+serious problems عند مين؟ عند الستات الحوامل
+
+117
+00:08:53,290 --> 00:08:58,290
+والناس اللي منعتهم ضعيفة ال IGG لل congenital
+
+118
+00:08:58,290 --> 00:09:03,820
+toxoplasmosis اللي هو بينتقل من الأم إلى الطفلالآن
+
+119
+00:09:03,820 --> 00:09:07,700
+تقريبًا من 10 إلى 20% من الـ Pregnant Woman اللي
+
+120
+00:09:07,700 --> 00:09:12,180
+بتوصاب بتكسب لازماجوندياي تظهر عندها بعض الأعراض
+
+121
+00:09:12,180 --> 00:09:16,520
+معظم الأعراض اللي بتظهر حمّة بسيطة مع لمثا
+
+122
+00:09:16,520 --> 00:09:21,920
+دينوباثي تضخم في الغدد اللمفاوية الآن إذا أصيبت
+
+123
+00:09:21,920 --> 00:09:26,880
+الأم بتكسب لازماجوندياي خلال الحمل الطفالها ده
+
+124
+00:09:26,880 --> 00:09:29,740
+ممكن إنه ينتقل عبر الـ placenta إلى ال baby
+
+125
+00:09:30,530 --> 00:09:33,590
+وبالتالي infection may be transmitted to the fetus
+
+126
+00:09:33,590 --> 00:09:39,550
+transplacenta يعني أن طبابي بتوصلوا الـ Toxo أو
+
+127
+00:09:39,550 --> 00:09:43,950
+الطفال من خلال الـ Placenta طيب الطفل لما بيوصلوا
+
+128
+00:09:43,950 --> 00:09:47,990
+الطفال إيش ممكن يصير فيه؟ فهذا بيعتمد على في أي
+
+129
+00:09:47,990 --> 00:09:51,330
+شهر من الحمل الست أصيبة بقولك إذا كان ال infection
+
+130
+00:09:51,330 --> 00:09:56,530
+كانت في فترة قصيرة قبل الحمل تمام within a few
+
+131
+00:09:56,530 --> 00:09:59,370
+weeks before يعني في الأسبوع القليلة قبل فترة
+
+132
+00:09:59,370 --> 00:10:04,880
+الحملCarriers a 1% risk or below of transmission
+
+133
+00:10:04,880 --> 00:10:10,160
+to the baby يعني فرصة انتقالها إلى ال baby أقل من
+
+134
+00:10:10,160 --> 00:10:17,900
+1% تمام؟ لكن إذا وصلت لل baby حيصير فيه خطر من أن
+
+135
+00:10:17,900 --> 00:10:21,500
+يصير miscarriageيعني إذا فعلاً الجرثومة وصلت
+
+136
+00:10:21,500 --> 00:10:25,040
+للبابي هيبقى في احتمال كبير أن يصير abortion أو
+
+137
+00:10:25,040 --> 00:10:28,160
+miscarriage تمام؟ إذن هي بس الفرصة إنها توصل
+
+138
+00:10:28,160 --> 00:10:31,740
+للبابي أقل من 1% لكن في ال .. لو وصلت غالباً بيصير
+
+139
+00:10:31,740 --> 00:10:35,980
+إجهاض if infection was in the first trimester يعني
+
+140
+00:10:35,980 --> 00:10:40,260
+لو العتوى صارت في الأسبوع الأول من الحمل في ال ..
+
+141
+00:10:40,260 --> 00:10:43,340
+في ال trimester عفوا الأول من الحمل اللي هو أول
+
+142
+00:10:43,340 --> 00:10:49,110
+تلت شهورمن الأسبوع الأول للأسبوع الأتناش عادة
+
+143
+00:10:49,110 --> 00:10:54,750
+الستات اللي أصيبوا عشرة إلى خمستاشر في المية منهم
+
+144
+00:10:54,750 --> 00:10:58,810
+ممكن ينقلوها لل baby a baby infected at this stage
+
+145
+00:10:58,810 --> 00:11:02,510
+has a risk of being miscarried or stillbirth يعني
+
+146
+00:11:02,510 --> 00:11:06,590
+ممكن يصير abortion أو أنه يموت في داخل الرحم وبعد
+
+147
+00:11:06,590 --> 00:11:12,490
+هيك يصيرله abortionإذن كل ما اتقدمنا في شهور الحمل
+
+148
+00:11:12,490 --> 00:11:15,670
+كل ما كانت الخطورة على ال baby أكتر لغاية الآن
+
+149
+00:11:15,670 --> 00:11:22,030
+الفرصة قبل الحمل 1% فرصة انتقالها لل baby لكن في
+
+150
+00:11:22,030 --> 00:11:28,930
+ال first trimester من 10 إلى 15% طيب هنا لو ال
+
+151
+00:11:28,930 --> 00:11:32,630
+infection صارت في second trimester من الحمل يعني
+
+152
+00:11:32,630 --> 00:11:37,790
+في الأسبوع 13 إلى 28فرصة انتقالها للـ baby هتزيد
+
+153
+00:11:37,790 --> 00:11:42,970
+هتصير 25% لكن الـ baby اللي بيصاب في هذه المرحلة
+
+154
+00:11:42,970 --> 00:11:47,690
+غالبا ما بيصير له miscarriage وإنما بيظل موجود لكن
+
+155
+00:11:47,690 --> 00:11:52,030
+غالبا بيصير عنده تشوهات خلقية زي Hydrocephaly كبير
+
+156
+00:11:52,030 --> 00:11:56,150
+حجم الشمشمة تجمع سوائل فيها calcification of the
+
+157
+00:11:56,150 --> 00:11:59,970
+brain retinocarditis اللي هو inflammation of the
+
+158
+00:11:59,970 --> 00:12:02,770
+retina التهاب في شبكية العين قد يؤدي إلى العمى
+
+159
+00:12:03,180 --> 00:12:06,380
+microcephaly صغر حجم الجمجمة neurological
+
+160
+00:12:06,380 --> 00:12:09,740
+disorders مشاكل اللي لو انتقلت في الـ third
+
+161
+00:12:09,740 --> 00:12:14,280
+trimester في آخر تلت شهور من الحمل من 29 إلى 40
+
+162
+00:12:14,280 --> 00:12:19,540
+أسبوع هنا عادة الفرصة هتصير عالية للانتقال من 70
+
+163
+00:12:19,540 --> 00:12:25,100
+إلى 80% هتصير فرصة انتقال إلى ال baby هنا ال baby
+
+164
+00:12:25,100 --> 00:12:30,120
+مش هيصيرله غالبا مسكرج ولا حاجة وهينولد طبيعي لكن
+
+165
+00:12:30,120 --> 00:12:35,940
+عدد كبير منهمبيصير عندهم symptoms بعد الولادة يعني
+
+166
+00:12:35,940 --> 00:12:40,320
+ممكن يصير عندهم eye damage ممكن يصير عندهم بعض الـ
+
+167
+00:12:40,320 --> 00:12:45,420
+neurological problems أو disorders من الحاجات
+
+168
+00:12:45,420 --> 00:12:48,780
+الشائعة اللي ممكن تصير كمضاعفة للـ toxoplasmosis
+
+169
+00:12:48,780 --> 00:12:52,020
+سواء الـ congenital أو الـ acute infection اللي هو
+
+170
+00:12:52,020 --> 00:12:56,760
+الـ retinocarditis أو ocular toxoplasmosis عادةً
+
+171
+00:12:56,760 --> 00:12:59,440
+هذا بينتج من الـ reactivation of congenital
+
+172
+00:12:59,440 --> 00:13:05,000
+infectionيعني إعادة تنشيط للطفال or part of acute
+
+173
+00:13:05,000 --> 00:13:09,040
+infection كيف بيصير هذا؟ لما ال organism بيوصل
+
+174
+00:13:09,040 --> 00:13:13,640
+للعين قبر ال blood stream طبعا هناك ممكن تبقى
+
+175
+00:13:13,640 --> 00:13:17,500
+المناعة تحت الشخص كويسة يعني ال immune status
+
+176
+00:13:17,500 --> 00:13:25,100
+كويسة فبتلالي هتلاقي أن الطفال هيقعد في العين ومش
+
+177
+00:13:25,100 --> 00:13:30,310
+هيعمل مشاكل تمام؟الان في لحظة معينة ممكن تضعف
+
+178
+00:13:30,310 --> 00:13:34,170
+المناعة فلقيت لو ضعفت المناعة الطفل هذا هيتنشط
+
+179
+00:13:34,170 --> 00:13:38,710
+ويبدأ يطلق ال parasites تمام ال parasites هذه
+
+180
+00:13:38,710 --> 00:13:42,490
+هتعمل inflammatory response هيؤذي شبكية العين الان
+
+181
+00:13:42,490 --> 00:13:48,950
+فينا بقولك يعني انه كيف ايش اللي بيصير كرد فعل
+
+182
+00:13:48,950 --> 00:13:52,990
+لجهاز المناعة assist form و assist هذه مقاومة
+
+183
+00:13:52,990 --> 00:13:56,310
+لجهاز المناعةوالاتنين بيكونوا على الحياد يعني ولا
+
+184
+00:13:56,310 --> 00:13:59,710
+واحد فيهم بأذى التاني فتتحول ل chronic infection
+
+185
+00:13:59,710 --> 00:14:02,730
+ال cyst موجودة يعني لو الدكتور اتطلع على الشبكية
+
+186
+00:14:02,730 --> 00:14:09,570
+ممكن يشوف ال cyst في العين تمام whenever the host
+
+187
+00:14:09,570 --> 00:14:13,190
+immune function declines for any reason لأي سبب
+
+188
+00:14:13,190 --> 00:14:16,110
+اتغيرت ال host immune function ال cyst و ال
+
+189
+00:14:16,110 --> 00:14:18,890
+rupture ال cyst اللي اتكونت هذي هيصير لها rupture
+
+190
+00:14:19,390 --> 00:14:22,910
+وهي تطلع ال organism على ال retina على الشبكية
+
+191
+00:14:22,910 --> 00:14:26,970
+وبتعمل inflammatory process طبعا ال inflammatory
+
+192
+00:14:26,970 --> 00:14:31,870
+process ممكن تعمل lesion نتيجة التفاعل ممكن ال
+
+193
+00:14:31,870 --> 00:14:36,870
+healing يصير على الالشبكية نفسها وانتوا عارفين أي
+
+194
+00:14:36,870 --> 00:14:40,810
+حاجة عال الشبكية ممكن تعمل الاسكار وممكن تأثر على
+
+195
+00:14:40,810 --> 00:14:44,190
+القلبي ال diagnosis of toxoplasmosis الفحوصات يعني
+
+196
+00:14:44,190 --> 00:14:48,650
+قد تكون serological tests أو PCR أو ناخد مقطع من
+
+197
+00:14:48,650 --> 00:14:52,210
+النسيج histologic determination of the parasite و
+
+198
+00:14:52,210 --> 00:14:56,850
+بنسبغها بال immunobricosidase 2 و بنشوف ال
+
+199
+00:14:56,850 --> 00:14:59,970
+parasite إذا كان موجود ممكن نعمل isolation لل
+
+200
+00:14:59,970 --> 00:15:04,840
+organismفي طرق أخرى أقل شيوعا زي الـ Demonstration
+
+201
+00:15:04,840 --> 00:15:07,660
+of Antigen in Serum and Body Fluids إن ندور على
+
+202
+00:15:07,660 --> 00:15:10,700
+الـ Antigen مش على الـ Antibody فينا فحص اسمه A
+
+203
+00:15:10,700 --> 00:15:14,680
+Toxoplasmic Skin Test Antigen Specific Lymphocyte
+
+204
+00:15:14,680 --> 00:15:18,820
+Transformation فلقيت إحنا هركز بشكل أساسي على الـ
+
+205
+00:15:18,820 --> 00:15:22,840
+Serological Serological Test فينا فحصات سيرولوجي
+
+206
+00:15:22,840 --> 00:15:27,520
+كتير عملت عشان الـ Toxoplasmosisطبعاً بندور على
+
+207
+00:15:27,520 --> 00:15:30,820
+الـ Antibody إذا طلع عندنا الفحص positive المفروض
+
+208
+00:15:30,820 --> 00:15:35,740
+نشوف يعني هل هو IgG أو IgM؟ هل ال infection قديمة؟
+
+209
+00:15:35,740 --> 00:15:39,740
+هل هي مثلا recent infection؟ وهي اللي أثرت وعملت
+
+210
+00:15:39,740 --> 00:15:42,340
+abortion أو عملت تشوهات عند الجنين ولا لأ؟ لذا
+
+211
+00:15:42,340 --> 00:15:47,980
+لازم نحدد نوع الـ Antibody الموجود إذا كان فيه
+
+212
+00:15:47,980 --> 00:15:50,320
+أنشكة في التكسو أو الناس معاه أولاً الـ IgG
+
+213
+00:15:50,320 --> 00:15:57,270
+Antibodyالـ IgG Antibodies عادة بتظهر خلال أسبوع
+
+214
+00:15:57,270 --> 00:16:01,690
+إلى أسبوعين من الـ infection وبتوصل الـ peak من
+
+215
+00:16:01,690 --> 00:16:06,390
+شهر إلى شهرين ممكن بعد هيك تنزل لكن لا تنعدم يعني
+
+216
+00:16:06,390 --> 00:16:10,630
+ممكن تظلها طول الحياة وبيختلف هذا من شخص لشخص
+
+217
+00:16:10,630 --> 00:16:14,870
+القرق المستخدمة في قياس الـ IgG فيه أن السابين
+
+218
+00:16:14,870 --> 00:16:19,660
+فيلدمان دايتست إليزاimmunofluorescence assay and
+
+219
+00:16:19,660 --> 00:16:22,860
+modified direct agglutination test IGM antibodies
+
+220
+00:16:22,860 --> 00:16:29,260
+IGM antibodies عادة بترتفع من خمس أيام إلى أسبوع
+
+221
+00:16:29,260 --> 00:16:34,860
+بعد الـ acute infection بتوصل لـ maximum خلال واحد
+
+222
+00:16:34,860 --> 00:16:40,340
+وعشرين يوم وبتنزل أسرع من الـ IgG the most
+
+223
+00:16:40,340 --> 00:16:43,900
+commonly used test for the measurement of IGM برضه
+
+224
+00:16:43,900 --> 00:16:47,840
+الـ ELISA الimmune fluorescenceالـ Immunosorbent
+
+225
+00:16:47,840 --> 00:16:54,480
+Agglutination Assay الآن من الفحصات اللي بنكشف عن
+
+226
+00:16:54,480 --> 00:16:57,900
+الـ Antibodies من خلالها اللي هو Sabine Fieldman
+
+227
+00:16:57,900 --> 00:17:03,340
+-Dye Test الفحص فكرته بسيطة كتير أنه أنا بجيب عينة
+
+228
+00:17:03,340 --> 00:17:07,260
+الـ Serum و بجيب الطفل نفسه تكسب Plasma
+
+229
+00:17:07,260 --> 00:17:13,060
+Etrophosite بحط عينة الـ Serum مع الـ Etrophosite
+
+230
+00:17:13,060 --> 00:17:16,610
+مع complementتمام؟ الـ complement عشان يعمل
+
+231
+00:17:16,610 --> 00:17:20,610
+activation للـ antigen-antibody reaction هلقيت،
+
+232
+00:17:20,610 --> 00:17:24,570
+إذا كان الـ antibody موجود في عينة السيرام هيتفاعل
+
+233
+00:17:24,570 --> 00:17:28,170
+مع الـ trophocyte في وجود الـ complement، بتعرفي
+
+234
+00:17:28,170 --> 00:17:30,750
+إن الـ complement لما بتكون موجودة بتعمل license
+
+235
+00:17:30,750 --> 00:17:33,630
+للـ cell membrane إذا اتفاعل الـ antigen والـ
+
+236
+00:17:33,630 --> 00:17:37,450
+antibody واتنشطت الـ complement هيطلف الـ cell
+
+237
+00:17:37,450 --> 00:17:43,470
+membrane بتاع الـ toxin تمام؟لو كان الـ Antibody
+
+238
+00:17:43,470 --> 00:17:46,870
+مش موجود مش هيتم التفاعل و هيظل الـ Cell Membrane
+
+239
+00:17:46,870 --> 00:17:50,770
+كويس يعني مش هيطلع طيب أنا كيف بدي أستدل هل الـ
+
+240
+00:17:50,770 --> 00:17:56,570
+Cell Membrane ضاله Intact ولا صارله Lysis؟ عن طريق
+
+241
+00:17:56,570 --> 00:18:01,290
+إضافة صبغة الميسيليني بلو هلأ الميسيليني بلو
+
+242
+00:18:01,290 --> 00:18:05,410
+المفروض بتصبغ الخلية الكاملة إذا كانت خلية كاملة و
+
+243
+00:18:05,410 --> 00:18:08,890
+إلها Cell Membrane هيدخل الميسيليني بلو لداخلها و
+
+244
+00:18:08,890 --> 00:18:12,200
+يصبغها و مش هيطلع منهالكن لو كان الـ Cell Membrane
+
+245
+00:18:12,200 --> 00:18:17,660
+تالف بالتالي هتلاقي إنه الخلية مش هتنصبغ إذن
+
+246
+00:18:17,660 --> 00:18:21,080
+الخلية المصبوغة بتدل على إن العينة Negative مافيش
+
+247
+00:18:21,080 --> 00:18:24,640
+فيها Antibody الخلية الغير مصبوغة بتدل على إن
+
+248
+00:18:24,640 --> 00:18:28,600
+الخلية Positive يعني الـ Cell Membrane فقدت عن
+
+249
+00:18:28,600 --> 00:18:31,400
+طريق الـ Antibody الموجود في عينة الـ Serum دلنا
+
+250
+00:18:31,400 --> 00:18:34,780
+نشوف إيش موجودThis is based on the presence of
+
+251
+00:18:34,780 --> 00:18:37,720
+certain antibodies that prevent Mycelin Blue dye
+
+252
+00:18:37,720 --> 00:18:40,140
+from entering the cytoplasm of Toxoplasma
+
+253
+00:18:40,140 --> 00:18:43,800
+organisms.Patient serum is treated with Toxoplasma
+
+254
+00:18:43,800 --> 00:18:49,240
+trophozoite patient serum and complement as
+
+255
+00:18:49,240 --> 00:18:53,160
+activator and then incubated بعمل incubation بعد
+
+256
+00:18:53,160 --> 00:18:56,260
+ال incubation Mycelin Blue is added عشان أشوف هل
+
+257
+00:18:56,260 --> 00:18:59,230
+هتنصبه ولا مش هتنصبهإذا كانت الـ Antitoxin
+
+258
+00:18:59,230 --> 00:19:03,470
+Antibodies موجودة في السيروم لأن هذه الانتباطات تم
+
+259
+00:19:03,470 --> 00:19:07,750
+اكتشافها بـ Complement وكذلك برسايت ممبران تكسو
+
+260
+00:19:07,750 --> 00:19:11,890
+بلازمة تروفوزايت ليسوا مظهرين مظهرين ليسوا مظهرين
+
+261
+00:19:11,890 --> 00:19:15,810
+يعني نتيجة جيدة إذا لم يكن هناك انتباطات تروفوزايت
+
+262
+00:19:15,810 --> 00:19:21,110
+مع ممبران مستقل مظهرين ومظهرين تحت الميكروسكوب
+
+263
+00:19:21,110 --> 00:19:26,750
+اللي هي نتيجة أخرى للكشف عن الـ IgM Antibodies
+
+264
+00:19:27,310 --> 00:19:30,450
+التقنية هذه بتجمع ما بين الـ immunosorbent والـ
+
+265
+00:19:30,450 --> 00:19:34,930
+agglutination بتعتمد فكرتها كتير بسيطة إنه في عندى
+
+266
+00:19:34,930 --> 00:19:39,290
+ولات الول هذه على شكل U-shape دائرية القاع داعها
+
+267
+00:19:39,290 --> 00:19:44,750
+دائري مثبت عليها Anti-IgM مثبت عليها Anti-IgM اللي
+
+268
+00:19:44,750 --> 00:19:47,890
+هو هذا اللون الأزرق فلاقيت أنا بضيف عينة الـ serum
+
+269
+00:19:47,890 --> 00:19:52,610
+إذا كان الـ IgM موجود هيربط مع الـ Anti-IgM بعدين
+
+270
+00:19:52,610 --> 00:19:56,860
+بعمل washing عشان أتخلص من أي إجزة من الـ plasmaأو
+
+271
+00:19:56,860 --> 00:20:02,780
+من الـ Serum تمام الخطوة اللي بعدها بضيف Particles
+
+272
+00:20:02,780 --> 00:20:07,440
+أو Vessels ملونة محمل عليها الـ Antigen هلاقيت الـ
+
+273
+00:20:07,440 --> 00:20:11,680
+Vessels هذه إذا لاقت الـ Antibody الـ IgM موجود
+
+274
+00:20:11,680 --> 00:20:16,680
+هتروحه هي مرتبطة فيه و تظهر على شكل انتشار على قاع
+
+275
+00:20:16,680 --> 00:20:19,620
+الـ Well يعني هتكون الصورة عندي على شكل انتشار
+
+276
+00:20:19,620 --> 00:20:26,130
+شايفين كيف؟ بتكون منتشرة الآنالخيار التاني إنه
+
+277
+00:20:26,130 --> 00:20:29,030
+يكون الـ Serum مافيه Antibody عن العينة Negative
+
+278
+00:20:29,030 --> 00:20:33,930
+إذا كانت العينة Negative مش هيرتبط الـ IgM من الـ
+
+279
+00:20:33,930 --> 00:20:37,550
+Well وبالتالي الحبيبات هذه الـ Vessels الخضراء
+
+280
+00:20:37,550 --> 00:20:41,560
+اللي أنا ضفتهاهتتجمع في القاع بدل من أن تنتشر على
+
+281
+00:20:41,560 --> 00:20:44,820
+جدران الـ Well هتتجمع في القاع لأنها ما لقيت حاجة
+
+282
+00:20:44,820 --> 00:20:49,760
+ترتبط فيها فهتنزل على شكل نقطة في قاع ال tube طبعا
+
+283
+00:20:49,760 --> 00:20:52,500
+اللي بيساعدني أشوف ال agglutination أو التجمع على
+
+284
+00:20:52,500 --> 00:20:56,500
+هذا الشكل إن ال well على شكل U فهذا بيسمح لها إنها
+
+285
+00:20:56,500 --> 00:21:00,460
+ما ارتبطت هتنزل في القاع ويظهر ال reaction بهذا
+
+286
+00:21:00,460 --> 00:21:04,020
+الشكل تجمع في قاع الأنبوبة إذا ال negative تجمع
+
+287
+00:21:04,020 --> 00:21:09,260
+بهذا الشكل ال positive انتشار تمام؟هنا في عندنا
+
+288
+00:21:09,260 --> 00:21:12,060
+ملاحظة حاجة بيسموها الـ Ectric phase الـ Ectric
+
+289
+00:21:12,060 --> 00:21:15,580
+phase هي مرحلة الـ switching ما بين الـ IgM و IgG
+
+290
+00:21:15,580 --> 00:21:19,380
+أحياناً هذه المرحلة بتخدعني بيكونوا التانين فيها
+
+291
+00:21:19,380 --> 00:21:25,600
+with low level نيجي للـ IgA antibodies ممكن الـ
+
+292
+00:21:25,600 --> 00:21:28,900
+IgA antibodies تكون موجودة ونحددها في الـ serum في
+
+293
+00:21:28,900 --> 00:21:32,790
+حالات الـ acute infectionسواء acute أو congenital
+
+294
+00:21:32,790 --> 00:21:36,090
+infection ممكن نحددها بالـ ELISA أو بالتكنيك اللي
+
+295
+00:21:36,090 --> 00:21:38,510
+حكينا عنها قبل بشوية اللي هي immunosorbent
+
+296
+00:21:38,510 --> 00:21:42,350
+agglutination assay بدل ما أثبت عليه الـ Anti-IgM
+
+297
+00:21:42,350 --> 00:21:49,990
+بثبت Anti-IgA الـ IgA بظهر بالـ Serum لما يتكون
+
+298
+00:21:49,990 --> 00:21:53,110
+العين affected يعني لما يوصل ال parasite للعين
+
+299
+00:21:53,110 --> 00:21:56,730
+ويتكون فعلا العين اتأثرت أو موجود ال parasite في
+
+300
+00:21:56,730 --> 00:22:00,830
+العينin a number of newborn with congenital
+
+301
+00:22:00,830 --> 00:22:03,950
+toxoplasmosis and negative IgM antibodies the
+
+302
+00:22:03,950 --> 00:22:06,850
+surgical diagnosis has been established by the
+
+303
+00:22:06,850 --> 00:22:11,210
+presence of IgA and IgM يعني أحيانا الطفل أول ما
+
+304
+00:22:11,210 --> 00:22:15,970
+بنولد لو أنا شاكة أنه عنده تكسو ممكن ال IgM يبقى
+
+305
+00:22:15,970 --> 00:22:20,330
+عنده negative لكن ممكن ألاقي ال IgG positive أو ال
+
+306
+00:22:20,330 --> 00:22:26,790
+IgAIgE Antibody ممكن يتحدد برضه بالـ ELISA في الـ
+
+307
+00:22:26,790 --> 00:22:29,550
+Acutely Infected Adult وفي حالات الـ Congenital
+
+308
+00:22:29,550 --> 00:22:35,790
+Toxoplasmosis ال duration of IgE قليلة كتير أقل من
+
+309
+00:22:35,790 --> 00:22:39,930
+الـ IgM أو الـ IgA يعني ممكن يساعدني في التشخيص ال
+
+310
+00:22:39,930 --> 00:22:42,250
+recent acquired infection لأنه دُغري بينجل بعدين
+
+311
+00:22:42,250 --> 00:22:45,290
+جي للـ histological diagnosis ممكن ال diagnosis
+
+312
+00:22:45,290 --> 00:22:50,560
+نعمل من خلال ال biopsy ناخد ال tissue sectionونشوف
+
+313
+00:22:50,560 --> 00:22:54,180
+الـ Parasite فيه مباشرة ممكن نستخدم
+
+314
+00:22:54,180 --> 00:22:58,460
+Immunofluorescence Stain عشان نشوف ال Parasite
+
+315
+00:22:58,460 --> 00:23:02,400
+ممكن نستخدم Sabine Field Man Stain طبعا هذه
+
+316
+00:23:02,400 --> 00:23:06,000
+التقنية مش كتير يعنى مش روتينية ومتستخدمش كتير
+
+317
+00:23:06,000 --> 00:23:09,340
+لأنه أول إشي العينات هذه صعب أني أحصل عليها يعني
+
+318
+00:23:09,340 --> 00:23:12,300
+أنا بدأ أخد Tissue Biopsy عشان أشخص Toxin لأ يعني
+
+319
+00:23:12,300 --> 00:23:16,380
+حاجة مش عملية بالمرة تفضل يقول ممكن بغرض الأبحاث
+
+320
+00:23:16,380 --> 00:23:19,930
+أنها تنعمل أو تنعمل لل Animals مثلاأما للـ human
+
+321
+00:23:19,930 --> 00:23:24,810
+عادة ما يعني مش حاجة روتينية لل isolation برضه هذه
+
+322
+00:23:24,810 --> 00:23:30,530
+طريقة يعني مش مابتنعملش كتير و مش روتينية أنه أخد
+
+323
+00:23:30,530 --> 00:23:34,450
+ال parasite و أعمله isolation من ال blood أو من أي
+
+324
+00:23:34,450 --> 00:23:38,530
+body fluid و أعمله culture أو أعمله animal
+
+325
+00:23:38,530 --> 00:23:41,350
+inoculation و أشوف النتيجة بتاعته بس طبعا زي ما
+
+326
+00:23:41,350 --> 00:23:47,080
+قلتلكم هي مكلفة و بتغلب و بتاخد وقت طويلالـ PCR
+
+327
+00:23:47,080 --> 00:23:51,800
+إنه نشوف الـ DNA للفيروس للـ Parasite وهذا من
+
+328
+00:23:51,800 --> 00:23:55,960
+الفحصات اللي بتنعمل على الـ amniotic fluid طبعا
+
+329
+00:23:55,960 --> 00:24:02,060
+إذا كانت الأم يعني ظهر عند ال baby هذا دلائل تشوه
+
+330
+00:24:02,060 --> 00:24:06,940
+مثلا أو فيه خطورة على ال baby معينة فيه أعراض تقصه
+
+331
+00:24:06,940 --> 00:24:09,880
+يعني الدكتور كتير مرجح إنه يكون فيه تقصه Plasmosis
+
+332
+00:24:09,880 --> 00:24:13,400
+وفحصات الـ serology لا قادرة تثبت ولا قادرة تنفي
+
+333
+00:24:13,400 --> 00:24:16,990
+إنه فيه فعلا infection ولا لأممكن ياخدوا عينة
+
+334
+00:24:16,990 --> 00:24:20,090
+Amniotic Flu ويعملوا لها PCR عشان يشوفوا الـ DNA
+
+335
+00:24:20,090 --> 00:24:25,390
+للطفال ممكن ياخدوا Fetal Blood Sampling ياخدوا
+
+336
+00:24:25,390 --> 00:24:28,850
+عينة blood من الـ umbilical cord الفيتس خلال الحمل
+
+337
+00:24:28,850 --> 00:24:33,870
+بس هاد الطريقة يعني invasive وممكن تشكل risk على
+
+338
+00:24:33,870 --> 00:24:36,390
+ال baby يعني ممكن هي نفسها تكون خطيرة على ال baby
+
+339
+00:24:37,150 --> 00:24:40,370
+عشان هيك يعني كانت زمان تستخدم في شكل أساسي بس
+
+340
+00:24:40,370 --> 00:24:44,830
+الآن ماتستخدمش لأنها الـ Ocular Disease إنه كيف
+
+341
+00:24:44,830 --> 00:24:47,390
+بدنا نحدد إذا كان فيه مشكلة في العين ولا لأ طبعا
+
+342
+00:24:47,390 --> 00:24:51,130
+هذه بتبين إن الطبيب العيون بيشوف ال lesion في
+
+343
+00:24:51,130 --> 00:24:55,830
+العين بالإضافة لـ Serological Testing قياس ال
+
+344
+00:24:55,830 --> 00:24:57,430
+level الخاصة لل IGA
+
+345
+00:25:00,320 --> 00:25:03,700
+نيجي للـ Chlamydia الـ Chlamydia برضه من الأشياء
+
+346
+00:25:03,700 --> 00:25:06,320
+اللي ممكن أو من البراسايت اللي ممكن تأذي الأم
+
+347
+00:25:06,320 --> 00:25:09,780
+الحامل وتسبب Abortion هي عبارة عن Obligate
+
+348
+00:25:09,780 --> 00:25:13,680
+Intracellular Parasite في منها أكتر من نوع في منها
+
+349
+00:25:13,680 --> 00:25:18,020
+Chlamydia Cetaceae وفي منها Lymphogranulomatous
+
+350
+00:25:18,020 --> 00:25:24,060
+وفي منها Trachomatous وفي Oculogenitis نيجي لأول
+
+351
+00:25:24,060 --> 00:25:29,370
+نوع اللي هو Cetacosis عبارة عنال respiratory
+
+352
+00:25:29,370 --> 00:25:33,450
+disease بيجي من ال infected birds ال infected
+
+353
+00:25:33,450 --> 00:25:37,670
+birds بتطلع لكلاميديا سيتاسي في ال stool و ممكن عن
+
+354
+00:25:37,670 --> 00:25:43,150
+طريق الغبار ينتقل إلى الإنسان طبعا بسبب infection
+
+355
+00:25:43,150 --> 00:25:46,430
+في ال upper respiratory system و ممكن يؤدي إلى
+
+356
+00:25:46,430 --> 00:25:50,250
+نمونيا كيف بنعمل ال diagnosis طبعا حسب مكان العينة
+
+357
+00:25:50,250 --> 00:25:54,330
+هناخد sputum و ممكن نعمل blood testSmear to show
+
+358
+00:25:54,330 --> 00:25:57,530
+elementary bodies الـ elementary bodies هذه بتبين
+
+359
+00:25:57,530 --> 00:26:00,190
+في داخل الخلاهي الكلاميديا نفسها بتبين في داخل
+
+360
+00:26:00,190 --> 00:26:02,650
+الخلايا اللي لها شكل معين بيسمى بالـ elementary
+
+361
+00:26:02,650 --> 00:26:10,070
+bodies ممكن نعمل إليزا و ممكن نعمل PCR ممكن
+
+362
+00:26:10,070 --> 00:26:14,490
+نعمل لها isolation في اليكساك اللي هو ال
+
+363
+00:26:14,490 --> 00:26:19,970
+embryonated egg or intracerebral or intranasal في
+
+364
+00:26:19,970 --> 00:26:22,770
+المايس يعني ممكن نعمل animal oligulation أو egg
+
+365
+00:26:23,080 --> 00:26:25,440
+inoculation من الـ serological tests اللي ممكن
+
+366
+00:26:25,440 --> 00:26:28,500
+تنعمل complement fixation agglutination ال
+
+367
+00:26:28,500 --> 00:26:31,060
+neutralization هدول هناخدهم ال agglutination اللي
+
+368
+00:26:31,060 --> 00:26:32,620
+بنعرفه و ال complement fixation و ال
+
+369
+00:26:32,620 --> 00:26:36,700
+neutralization هناخدهم لقدام شاء الله ال
+
+370
+00:26:36,700 --> 00:26:39,900
+lymphogranuloma venerum عبارة عن venereal disease
+
+371
+00:26:39,900 --> 00:26:44,300
+بيأثر على ال lymph nodes بيعمل enlargement في ال
+
+372
+00:26:44,300 --> 00:26:47,700
+lymph nodes بالإضافة لإنه ممكن يعمل infection ل
+
+373
+00:26:47,700 --> 00:26:53,190
+اليوريثرة و طبعا يعني بيصاحبه systemic symptomsالـ
+
+374
+00:26:53,190 --> 00:26:55,810
+Lab diagnosis ممكن نعمل سمير عشان نشوف الـ
+
+375
+00:26:55,810 --> 00:26:58,750
+elementary body ممكن ناخد بيبس من الـ infected
+
+376
+00:26:58,750 --> 00:27:02,350
+lymph node برضه الـ bust cells اللي فيها ممكن يكون
+
+377
+00:27:02,350 --> 00:27:06,930
+فيها الـ elementary bodies الكلتر ما بتفيدني لأن
+
+378
+00:27:06,930 --> 00:27:09,810
+هي عبارة عن intracellular parasite فبالتالي لو
+
+379
+00:27:09,810 --> 00:27:14,590
+عملت كلتر هتبقى إقليمية Trachomatous طبعا هذه ممكن
+
+380
+00:27:14,590 --> 00:27:19,530
+تسبب conjunctivitis وهي عبارة عن sexually
+
+381
+00:27:19,530 --> 00:27:23,600
+transmitted diseaseهي ممكن تسبب تركومة عن طريق
+
+382
+00:27:23,600 --> 00:27:27,600
+نموها في الـ conjunctiva و القرنية للـ I يعني
+
+383
+00:27:27,600 --> 00:27:33,260
+بتنمو في أنسجة العين و بتسبب keratoconjunctivitis
+
+384
+00:27:33,260 --> 00:27:36,640
+بتسبب التهاب للعين كيف ممكن تنتقل للطفل خلال
+
+385
+00:27:36,640 --> 00:27:39,800
+الولادة عبر مرور الطفل في ال birth canal ممكن
+
+386
+00:27:39,800 --> 00:27:42,880
+تتأثر على الطفل و تعمل عنده مضاعفات زي ال
+
+387
+00:27:42,880 --> 00:27:46,640
+conjunctivitis و ممكن تعمل عنده كمان التهاب في
+
+388
+00:27:46,640 --> 00:27:48,480
+الرئتين اللي هو يومانيا
+
+389
+00:27:51,800 --> 00:27:56,920
+هنا بقولك إنه كتير في ستات بيصابوا فيها بس مايبقوا
+
+390
+00:27:56,920 --> 00:28:01,120
+عندهم أي أعراض لكن هذه مشكلتها إن لو ما اتعالجت
+
+391
+00:28:01,120 --> 00:28:04,920
+ممكن تعمل damage في ال reproductive system عند ال
+
+392
+00:28:04,920 --> 00:28:09,320
+female خاصة عند الفلوبيا نتيوب ممكن تعمل
+
+393
+00:28:09,320 --> 00:28:13,500
+infertility نتيجة تسديد الفلوبيا نتيوب ممكن تعمل
+
+394
+00:28:13,500 --> 00:28:18,240
+tubular pregnancy يعني تعمل حمل خارج الرحم اللي هو
+
+395
+00:28:18,240 --> 00:28:22,130
+في قناة فلوب وطبعا هذا بيكون كتير سيءالـ Lab
+
+396
+00:28:22,130 --> 00:28:25,190
+diagnosis ممكن نعمل I-swab عشان برضه نشوف الـ
+
+397
+00:28:25,190 --> 00:28:26,910
+elementary .. إيش هي الـ elementary bodies؟ قاعدين
+
+398
+00:28:26,910 --> 00:28:30,470
+إحنا بنقولها الـ elementary bodies هي لما بيجي
+
+399
+00:28:30,470 --> 00:28:34,610
+ميكروب مثلا زي الـChlamydia وبيجي الفاجوسايت تعمله
+
+400
+00:28:34,610 --> 00:28:40,210
+Fagocytosis هيظهر في داخل الخلية على شكل حبيبات
+
+401
+00:28:40,210 --> 00:28:44,890
+هذه هي يعني هذه الحبيبات اللي ظهر في داخل الخلية
+
+402
+00:28:45,960 --> 00:28:49,660
+ممكن نعمل الـ ELISA نشوف الـ IgM أو IgG أو IgE
+
+403
+00:28:49,660 --> 00:28:52,580
+نيجي للروبيلا الروبيلا اللى بتسمى كانت قديما
+
+404
+00:28:52,580 --> 00:28:58,240
+بالحصبة الألمانية عبارة عن mild disease بينتقل عن
+
+405
+00:28:58,240 --> 00:29:02,700
+طريق الجهاز التنفسى أو skin contact أو عن طريق الـ
+
+406
+00:29:02,700 --> 00:29:06,700
+congenital يعني من الطفل ينتقل من الأم إلى طفلها
+
+407
+00:29:07,370 --> 00:29:11,190
+The virus can cross placental wall and infect the
+
+408
+00:29:11,190 --> 00:29:13,830
+fetus يعني هي مشكلته أنه ممكن يعدي لـ placenta
+
+409
+00:29:13,830 --> 00:29:17,750
+ويصيب الطفل this may lead to fetal death or
+
+410
+00:29:17,750 --> 00:29:21,670
+congenital defect يعني ممكن يؤدي إلى وفاة الطفل
+
+411
+00:29:21,670 --> 00:29:26,190
+وممكن يؤدي إلى birth defect من الحاجات اللي ممكن
+
+412
+00:29:26,190 --> 00:29:31,150
+تأثر أو تأديها لـ Bruxelles الـ hearing loss فقدان
+
+413
+00:29:31,150 --> 00:29:34,750
+السماعة تخلف عقلي mental retardation heart disease
+
+414
+00:29:35,540 --> 00:29:39,020
+retarded growth أثر على نمو الطفل blood disorders
+
+415
+00:29:39,020 --> 00:29:42,600
+vision problems مشاكل في الرؤية pneumonia عشان هيك
+
+416
+00:29:42,600 --> 00:29:47,560
+هذه من الأشياء اللي بيتطعموا إليها الأطفال الصغار
+
+417
+00:29:47,560 --> 00:29:52,880
+وحتى ال female بيعاد ينعطق جرعة داعمة في سن تقريبا
+
+418
+00:29:52,880 --> 00:29:57,200
+12 أو 13 سنة عشان يضمنوا إن ال title لل antibodies
+
+419
+00:29:57,200 --> 00:30:01,860
+لإلها موجود بشكل محترم وإنه مايأثر لو صار حمل بعد
+
+420
+00:30:01,860 --> 00:30:09,170
+هيك في المستقبل مايأثر على الأجنةفي عند الستات ال
+
+421
+00:30:09,170 --> 00:30:11,610
+lab diagnosis فيها فحوصات زي ال complement
+
+422
+00:30:11,610 --> 00:30:14,630
+fixation ال neutralization ال hemagglutination
+
+423
+00:30:14,630 --> 00:30:20,390
+inhibition ال إيليزا IGM and IGG طبعا هذه هي
+
+424
+00:30:20,390 --> 00:30:23,890
+الفحوصات هدول التانين احنا لسه هناخدهم لقدام ال
+
+425
+00:30:23,890 --> 00:30:26,910
+principle لإلهم اللي هو ال complement fixation و
+
+426
+00:30:26,910 --> 00:30:30,050
+ال neutralization ال hemagglutination inhibition
+
+427
+00:30:30,050 --> 00:30:34,650
+هذا إذا تدل على شاء بتدل على أنهالروبيلا بتعمل
+
+428
+00:30:34,650 --> 00:30:37,170
+hemagglutination لأنه مش احنا قولنا في بعض ال
+
+429
+00:30:37,170 --> 00:30:41,090
+viruses بتعمل hemagglutination فأنا لما بكون أدور
+
+430
+00:30:41,090 --> 00:30:45,090
+على ال serum لإلها ال antibody في ال serum إذا كان
+
+431
+00:30:45,090 --> 00:30:49,570
+موجود هيعمل hemagglutination inhibition تمام ممكن
+
+432
+00:30:49,570 --> 00:30:56,190
+نعمل إليزا IgM أو IgG الآن نحكي عن ال herpes virus
+
+433
+00:30:56,190 --> 00:31:00,690
+ال herpes في منه خمس أنواع الخمس أنواع one two
+
+434
+00:31:00,690 --> 00:31:05,320
+three four fiveخلّيني أشوف كل واحدة سمبل بسيطة عنه
+
+435
+00:31:05,320 --> 00:31:08,980
+«Virus 1» اللي هي بيسبب الحبيبات اللي بتظهر على
+
+436
+00:31:08,980 --> 00:31:14,020
+الشفتان بعد الحمّة بيسموه «fever blisters» هذا
+
+437
+00:31:14,020 --> 00:31:18,300
+عادة يعني بيكون موجود، latent، خامل، بعد أول مرة
+
+438
+00:31:18,300 --> 00:31:22,810
+بيصاب فيه الإنسانبمجرد ما تضعف المناعة نتيجة حمى
+
+439
+00:31:22,810 --> 00:31:26,210
+نتيجة نزلة برد بتلاقي بعاوض برجع يعني كل ما
+
+440
+00:31:26,210 --> 00:31:29,390
+الإنسان ضعفت مناعته بنشط هذا الفيروس و بعمل الحب
+
+441
+00:31:29,390 --> 00:31:33,050
+اللي ممكن تصيبنا كلنا بعد نزلات البرد نيجي لل
+
+442
+00:31:33,050 --> 00:31:36,970
+Herpes Simplex Virus 2 هذا عبارة عن sexually
+
+443
+00:31:36,970 --> 00:31:40,730
+transmitted disease بعمل blisters في منطقة
+
+444
+00:31:40,730 --> 00:31:45,650
+الجينيتالية نيجي
+
+445
+00:31:45,650 --> 00:31:49,190
+لل Herpes Simplex Virus اللي هو type 3الـ Type 3
+
+446
+00:31:49,190 --> 00:31:52,650
+هذا اللي هو عبارة عن الـ Varicose Loss Virus هذا
+
+447
+00:31:52,650 --> 00:31:57,110
+اللي بيسبب الـ Chickenpox اللي وجده للأطفال طبعا
+
+448
+00:31:57,110 --> 00:32:00,310
+هذا ممكن يصيب الأطفال أو يصيب الأكبار إذا أصاب
+
+449
+00:32:00,310 --> 00:32:03,210
+الأكبار غالبا بيجيهم على شكل ما يسمى بالحزام
+
+450
+00:32:03,210 --> 00:32:06,490
+الناري وبتبقى أعراضه شديدة على الأكبار مختلفة عن
+
+451
+00:32:06,490 --> 00:32:09,330
+الأصغار الأصغار بيكون بسيطة حمى يومين مع شوية
+
+452
+00:32:09,330 --> 00:32:12,890
+حبيبته وبينتهي بس مع الأكبار يعني بياخد وقت أطول
+
+453
+00:32:12,890 --> 00:32:20,310
+لغاية ما يطيببنتقل عن طريق العطس أو السعال من
+
+454
+00:32:20,310 --> 00:32:25,410
+الإنسان المريض إلى الإنسان السليماني طبعاً هذا
+
+455
+00:32:25,410 --> 00:32:29,590
+بشكل خطورة فعلية لو أصيبت فيه السد الحامل ممكن
+
+456
+00:32:29,590 --> 00:32:33,190
+يعمل abortion وممكن يعمل scarring لل baby ممكن
+
+457
+00:32:33,190 --> 00:32:36,070
+يعمل mal formation في ال limbs، في الأطراف، تشوّه
+
+458
+00:32:36,070 --> 00:32:41,610
+في الأطراف ممكن يعمل مشاكل في العين وفي الدماغ
+
+459
+00:32:41,610 --> 00:32:45,530
+نيجي لل diagnosis of herpes simplex virusأول حاجة
+
+460
+00:32:45,530 --> 00:32:48,310
+الـ Viral Culture بس طبعا احنا بندور على بدائي لأن
+
+461
+00:32:48,310 --> 00:32:52,830
+هذا الحل يعني مش سهل و بكلف و بياخد وقت في عندي
+
+462
+00:32:52,830 --> 00:32:56,150
+الـ Zinc Smear Zinc Smear هي عبارة عن كشطة بتتاخد
+
+463
+00:32:56,150 --> 00:33:01,310
+من مكان الحبيبات اللي طالع نتيجة الفيروس و بتنصبغ
+
+464
+00:33:01,310 --> 00:33:04,530
+تظهر فيها حاجة تسمى Zinc Cell اللي لها criteria
+
+465
+00:33:04,530 --> 00:33:09,310
+خاصة إذا طبعا اتوفر عندي Monoclonal Antibody ممكن
+
+466
+00:33:09,310 --> 00:33:12,950
+أعمل Direct Immunofluorescence Study ممكن نعمل PCR
+
+467
+00:33:13,540 --> 00:33:18,000
+ممكن نعمل type specific surgical test لـ Herpes
+
+468
+00:33:18,000 --> 00:33:20,840
+simplex virus نيجي للـ cytomegalovirus الـ
+
+469
+00:33:20,840 --> 00:33:23,500
+cytomegalovirus بيسمى بالـ salivary gland virus
+
+470
+00:33:23,500 --> 00:33:26,260
+which may be infect salivary glands or parotid
+
+471
+00:33:26,260 --> 00:33:30,800
+gland نيجي
+
+472
+00:33:30,800 --> 00:33:36,720
+للـ symptoms of cytomegalovirus تقريبا 90% من
+
+473
+00:33:36,720 --> 00:33:39,180
+الحالات الـ congenital مايبقاش عندهم أعراض عند
+
+474
+00:33:39,180 --> 00:33:46,400
+الولادة لكن منهمتقريبًا لغاية 15% بيعانوا من أهراض
+
+475
+00:33:46,400 --> 00:33:49,960
+في السنة الأولى زي «psychomotor» حاجات إلها علاقة
+
+476
+00:33:49,960 --> 00:33:54,080
+بالحركة «hearing» «neurologic» «ocular» «dental
+
+477
+00:33:54,080 --> 00:33:57,120
+abnormalities» with the first few years of life
+
+478
+00:33:57,120 --> 00:34:01,240
+«microcephaly» «Caesars» «pitagia» برضه ممكن إنها
+
+479
+00:34:01,240 --> 00:34:03,780
+اتبين يعني ممكن كل الأشياء هذه تظهر عندهم في
+
+480
+00:34:03,780 --> 00:34:10,910
+السنوات الأولى من العمر10% من الحالات بتطور سنسو
+
+481
+00:34:10,910 --> 00:34:15,790
+neural hearing loss يعني فقدان للسمع حاجة إلها
+
+482
+00:34:15,790 --> 00:34:19,910
+علاقة بالعصب السمعي يعني تأثر للعصب السمعي هو بتلف
+
+483
+00:34:19,910 --> 00:34:23,490
+بأثر على السمعي ‏easy لل lab diagnosis ممكن ناخد
+
+484
+00:34:23,490 --> 00:34:29,330
+pathological studiesإذا أنا أخدت tissue section
+
+485
+00:34:29,330 --> 00:34:34,210
+يعني بلاقي فيه الخلايا المصابة بعض ال particles أو
+
+486
+00:34:34,210 --> 00:34:38,690
+ال inclusions الخاصة بالفيروس واضحة ممكن بالفيروس
+
+487
+00:34:38,690 --> 00:34:45,130
+isolation أو نعمل إليزا IGG أو IGN هنا بقولك ال
+
+488
+00:34:45,130 --> 00:34:48,890
+IGG لما بعمله نادر لما بطلع نيجاتيب فإذا طلع معايا
+
+489
+00:34:48,890 --> 00:34:52,130
+positive لازم أعيده بعد أسبوعين أو تلت أسابيع إذا
+
+490
+00:34:52,130 --> 00:34:55,510
+لقيت ال titer زي ما هو فاعتبر العينة نيجاتيةإذا
+
+491
+00:34:55,510 --> 00:34:59,410
+رأيت فار ارتفاع في الـ tighter مع الكلام إن العينة
+
+492
+00:34:59,410 --> 00:35:02,750
+positive هيك بنكون مرنة على ال torch
+