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{"start": 591.08, "end": 591.36, "word": " host", "probability": 0.388671875}, {"start": 591.36, "end": 592.38, "word": " على", "probability": 0.5732421875}, {"start": 592.38, "end": 593.18, "word": " اللي", "probability": 0.928955078125}, {"start": 593.18, "end": 593.52, "word": " هو", "probability": 0.93408203125}, {"start": 593.52, "end": 594.2, "word": " السطح", "probability": 0.9541015625}, {"start": 594.2, "end": 594.48, "word": " اللي", "probability": 0.983642578125}, {"start": 594.48, "end": 594.82, "word": " هي", "probability": 0.9599609375}, {"start": 594.82, "end": 595.58, "word": " بدها", "probability": 0.9169921875}, {"start": 595.58, "end": 596.7, "word": " تخزوه", "probability": 0.9826171875}, {"start": 596.7, "end": 597.84, "word": " وبالتالي", "probability": 0.9435546875}], "temperature": 1.0}, {"id": 27, "seek": 62265, "start": 601.77, "end": 622.65, "text": "يبقى هذه أعضاء مش أعضاء حركة زي اللي هو الفلاديلة لأ هذه أعضاء البساق تعمل adhesion ايش adhesion يعني البساق البكتيريا على سطح اللي هو الكائن الحي اللي يبدأ تغذوه زي الإنسان زي الحيوان زي النبات مثلا", "tokens": [1829, 3555, 4587, 7578, 29538, 5551, 3615, 11242, 16606, 37893, 5551, 3615, 11242, 16606, 11331, 31747, 3660, 30767, 1829, 13672, 1829, 31439, 27188, 1211, 18513, 26895, 3660, 5296, 10721, 29538, 5551, 3615, 11242, 16606, 1975, 1211, 3555, 3794, 995, 4587, 6055, 25957, 1211, 614, 38571, 1975, 1829, 8592, 614, 38571, 37495, 22653, 29739, 3794, 995, 4587, 29739, 4117, 2655, 13546, 25528, 15844, 8608, 9566, 5016, 13672, 1829, 31439, 33251, 16373, 1863, 21542, 1829, 13672, 1829, 7251, 44510, 10721, 6055, 17082, 8848, 2407, 3224, 30767, 1829, 33688, 1863, 3794, 7649, 30767, 1829, 21542, 1829, 2407, 7649, 30767, 1829, 28239, 3555, 9307, 50113, 15040], "avg_logprob": -0.18689320012203697, "compression_ratio": 1.8602150537634408, "no_speech_prob": 0.0, "words": [{"start": 601.77, "end": 602.77, "word": "يبقى", "probability": 0.80487060546875}, {"start": 602.77, "end": 603.01, "word": " هذه", 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"text": "العضو الثالث في البكتيريا او القليل البكتيريا هي ال capsule الكبسول حقيقة من اساس زي احنا نقول يعني جشة البورتغانا من برا جشة البورتغانا البرتقالا ايش اهم شئ", "tokens": [6027, 3615, 11242, 2407, 6024, 104, 6027, 12984, 8978, 29739, 4117, 2655, 13546, 25528, 1975, 2407, 25062, 20292, 1211, 29739, 4117, 2655, 13546, 25528, 39896, 2423, 29247, 33251, 3555, 3794, 12610, 11331, 38436, 28671, 9154, 24525, 32277, 30767, 1829, 1975, 5016, 8315, 8717, 39648, 37495, 22653, 10874, 8592, 3660, 29739, 13063, 2655, 17082, 7649, 995, 9154, 4724, 23557, 10874, 8592, 3660, 29739, 13063, 2655, 17082, 7649, 995, 29739, 43500, 4587, 6027, 995, 1975, 1829, 8592, 1975, 16095, 13412, 19986], "avg_logprob": -0.2597656320780516, "compression_ratio": 1.8300653594771241, "no_speech_prob": 0.0, "words": [{"start": 624.41, "end": 625.23, "word": "العضو", "probability": 0.911376953125}, {"start": 625.23, "end": 626.07, "word": " الثالث", "probability": 0.91455078125}, {"start": 626.07, "end": 626.31, 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{"start": 1228.79, "end": 1229.05, "word": " من", "probability": 0.90283203125}, {"start": 1229.05, "end": 1229.65, "word": " الحرارة", "probability": 0.9808349609375}, {"start": 1229.65, "end": 1229.95, "word": " damage", "probability": 0.468017578125}, {"start": 1229.95, "end": 1230.25, "word": " يعني", "probability": 0.927978515625}, {"start": 1230.25, "end": 1230.89, "word": " التلف", "probability": 0.4732666015625}, {"start": 1230.89, "end": 1231.57, "word": " من", "probability": 0.5498046875}, {"start": 1231.57, "end": 1231.97, "word": " الحرارة", "probability": 0.98291015625}, {"start": 1231.97, "end": 1232.71, "word": " فبنحطه", "probability": 0.9239908854166666}, {"start": 1232.71, "end": 1233.19, "word": " في", "probability": 0.7607421875}, {"start": 1233.19, "end": 1233.61, "word": " filter", "probability": 0.59033203125}, {"start": 1233.61, "end": 1234.41, "word": " شبكت", "probability": 0.8421630859375}, {"start": 1234.41, "end": 1234.89, "word": " عيون", "probability": 0.7911783854166666}, {"start": 1234.89, "end": 1235.43, "word": " ال", "probability": 0.471435546875}, {"start": 1235.43, "end": 1235.87, "word": " جيجا", "probability": 0.834716796875}, {"start": 1235.87, "end": 1237.31, "word": " وبنصفيه", "probability": 0.80556640625}, {"start": 1237.31, "end": 1238.53, "word": " وبالتالي", "probability": 0.9255859375}, {"start": 1238.53, "end": 1238.89, "word": " احنا", "probability": 0.93310546875}, {"start": 1238.89, "end": 1239.57, "word": " بنطلعه", "probability": 0.924609375}, {"start": 1239.57, "end": 1239.95, "word": " نقي", "probability": 0.9345703125}, {"start": 1239.95, "end": 1240.81, "word": " من", "probability": 0.9921875}, {"start": 1240.81, "end": 1241.39, "word": " هذه", "probability": 0.90478515625}, {"start": 1241.39, "end": 1242.29, "word": " الشوائط", "probability": 0.865234375}, {"start": 1242.29, "end": 1242.61, "word": " دون", "probability": 0.9287109375}, {"start": 1242.61, "end": 1243.09, "word": " التلف", "probability": 0.9619140625}, {"start": 1243.09, "end": 1243.99, "word": " بالحرارة", "probability": 0.861474609375}, {"start": 1243.99, "end": 1244.27, "word": " دون", "probability": 0.87353515625}, {"start": 1244.27, "end": 1244.71, "word": " التلف", "probability": 0.984619140625}], "temperature": 1.0}, {"id": 51, "seek": 126044, "start": 1245.24, "end": 1260.44, "text": "بالحرارة انا اقرأ انه نستكفي بما وصلنا اليه في محاضرة الخامسة ونقف عند التطهير المرة القادمة يعني بأمر الله وانا شايف الأمور هتكون أحسن", "tokens": [3555, 6027, 5016, 2288, 9640, 3660, 1975, 8315, 1975, 4587, 2288, 10721, 16472, 3224, 8717, 14851, 4117, 41185, 4724, 15042, 4032, 36520, 8315, 45595, 3224, 8978, 3714, 5016, 46958, 25720, 33962, 10943, 3794, 3660, 4032, 1863, 4587, 5172, 43242, 16712, 9566, 3224, 13546, 9673, 25720, 25062, 18513, 46007, 37495, 22653, 4724, 10721, 29973, 21984, 4032, 7649, 995, 13412, 995, 33911, 16247, 2304, 13063, 8032, 2655, 30544, 5551, 5016, 3794, 1863], "avg_logprob": -0.10970510437454976, "compression_ratio": 1.703448275862069, "no_speech_prob": 6.139278411865234e-06, "words": [{"start": 1245.24, "end": 1246.08, "word": "بالحرارة", "probability": 0.9188639322916666}, {"start": 1246.08, "end": 1246.5, "word": " انا", "probability": 0.673828125}, {"start": 1246.5, "end": 1246.76, "word": " اقرأ", "probability": 0.8104248046875}, {"start": 1246.76, "end": 1247.0, "word": " انه", "probability": 0.942626953125}, {"start": 1247.0, "end": 1247.62, "word": " نستكفي", "probability": 0.919921875}, {"start": 1247.62, "end": 1248.84, "word": " بما", "probability": 0.9208984375}, {"start": 1248.84, "end": 1249.26, "word": " وصلنا", "probability": 0.9436848958333334}, {"start": 1249.26, "end": 1249.68, "word": " اليه", "probability": 0.945556640625}, {"start": 1249.68, "end": 1249.84, "word": " في", "probability": 0.810546875}, {"start": 1249.84, "end": 1250.86, "word": " محاضرة", "probability": 0.9075927734375}, {"start": 1250.86, "end": 1251.58, "word": " الخامسة", "probability": 0.9637451171875}, {"start": 1251.58, "end": 1252.14, "word": " ونقف", "probability": 0.8731689453125}, {"start": 1252.14, "end": 1252.5, "word": " عند", "probability": 0.99072265625}, {"start": 1252.5, "end": 1253.74, "word": " التطهير", "probability": 0.947265625}, {"start": 1253.74, "end": 1254.28, "word": " المرة", "probability": 0.97509765625}, {"start": 1254.28, "end": 1254.84, "word": " القادمة", "probability": 0.9939778645833334}, {"start": 1254.84, "end": 1255.94, "word": " يعني", "probability": 0.900146484375}, {"start": 1255.94, "end": 1256.6, "word": " بأمر", "probability": 0.8087565104166666}, {"start": 1256.6, "end": 1256.98, "word": " الله", "probability": 0.96044921875}, {"start": 1256.98, "end": 1257.66, "word": " وانا", "probability": 0.87548828125}, {"start": 1257.66, "end": 1258.04, "word": " شايف", "probability": 0.9845377604166666}, {"start": 1258.04, "end": 1259.1, "word": " الأمور", "probability": 0.8828125}, {"start": 1259.1, "end": 1259.82, "word": " هتكون", "probability": 0.9661458333333334}, {"start": 1259.82, "end": 1260.44, "word": " أحسن", "probability": 0.894775390625}], "temperature": 1.0}, {"id": 52, "seek": 127733, "start": 1260.64, "end": 1277.34, "text": "وهي أنا شايف طالباتي يعني بدوا يستوعبوا بس تقراوا أولا فأول وإن شاء الله ألتقيكم المحاضرة اللي جاية في اللي هو التطهير this infection شكرا لكم والسلام عليكم", "tokens": [2407, 3224, 1829, 41850, 13412, 995, 33911, 23032, 6027, 3555, 9307, 1829, 37495, 22653, 47525, 14407, 7251, 14851, 45367, 3555, 14407, 4724, 3794, 6055, 4587, 23557, 14407, 5551, 12610, 995, 6156, 10721, 12610, 4032, 28814, 1863, 13412, 16606, 21984, 5551, 1211, 2655, 38436, 24793, 9673, 5016, 46958, 25720, 13672, 1829, 10874, 995, 10632, 8978, 13672, 1829, 31439, 16712, 9566, 3224, 13546, 341, 11764, 13412, 4117, 23557, 5296, 24793, 16070, 3794, 37440, 25894, 24793], "avg_logprob": -0.13576857765784134, "compression_ratio": 1.5632183908045978, "no_speech_prob": 8.344650268554688e-07, "words": [{"start": 1260.64, "end": 1261.34, "word": "وهي", "probability": 0.7044270833333334}, {"start": 1261.34, "end": 1261.6, "word": " أنا", "probability": 0.442626953125}, {"start": 1261.6, "end": 1262.12, "word": " شايف", "probability": 0.9912109375}, {"start": 1262.12, "end": 1262.74, "word": " طالباتي", "probability": 0.800244140625}, {"start": 1262.74, "end": 1262.94, "word": " يعني", "probability": 0.88671875}, {"start": 1262.94, "end": 1263.38, "word": " بدوا", "probability": 0.895263671875}, {"start": 1263.38, "end": 1264.4, "word": " يستوعبوا", "probability": 0.958203125}, {"start": 1264.4, "end": 1264.66, "word": " بس", "probability": 0.977783203125}, {"start": 1264.66, "end": 1265.1, "word": " تقراوا", "probability": 0.829345703125}, {"start": 1265.1, "end": 1265.54, "word": " أولا", "probability": 0.8966471354166666}, {"start": 1265.54, "end": 1266.2, "word": " فأول", "probability": 0.8815104166666666}, {"start": 1266.2, "end": 1266.86, "word": " وإن", "probability": 0.759521484375}, {"start": 1266.86, "end": 1266.98, "word": " شاء", "probability": 0.9814453125}, {"start": 1266.98, "end": 1267.16, "word": " الله", "probability": 0.951171875}, {"start": 1267.16, "end": 1267.86, "word": " ألتقيكم", "probability": 0.9630859375}, {"start": 1267.86, "end": 1268.46, "word": " المحاضرة", "probability": 0.972900390625}, {"start": 1268.46, "end": 1268.58, "word": " اللي", "probability": 0.797119140625}, {"start": 1268.58, "end": 1269.4, "word": " جاية", "probability": 0.9236653645833334}, {"start": 1269.4, "end": 1269.72, "word": " في", "probability": 0.943359375}, {"start": 1269.72, "end": 1270.7, "word": " اللي", "probability": 0.948974609375}, {"start": 1270.7, "end": 1271.2, "word": " هو", "probability": 0.98486328125}, {"start": 1271.2, "end": 1273.16, "word": " التطهير", "probability": 0.978271484375}, {"start": 1273.16, "end": 1273.98, "word": " this", "probability": 0.3876953125}, {"start": 1273.98, "end": 1274.68, "word": " infection", "probability": 0.9404296875}, {"start": 1274.68, "end": 1275.76, "word": " شكرا", "probability": 0.96728515625}, {"start": 1275.76, "end": 1276.24, "word": " لكم", "probability": 0.953857421875}, {"start": 1276.24, "end": 1276.84, "word": " والسلام", "probability": 0.8585611979166666}, {"start": 1276.84, "end": 1277.34, "word": " عليكم", "probability": 0.968017578125}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1278.2585, "duration_after_vad": 1251.9147187499998}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/LWHQ2dWz8vI.srt b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/LWHQ2dWz8vI.srt
new file mode 100644
index 0000000000000000000000000000000000000000..1bc39631e64179a3535c1fdab463fc41fae4d601
--- /dev/null
+++ b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/LWHQ2dWz8vI.srt
@@ -0,0 +1,1279 @@
+1
+00:00:05,570 --> 00:00:08,750
+أعوذ بالله من الشيطان الرجيم بسم الله الرحمن
+
+2
+00:00:08,750 --> 00:00:13,550
+الرحيم الحمد لله وأقف أصلي وأسلم على النبي مصطفى
+
+3
+00:00:13,550 --> 00:00:18,310
+أبدأ اليوم في المحاضرة الثلاثين في هذا المساق
+
+4
+00:00:18,310 --> 00:00:27,050
+microbiology of the eye  الـ herpes simplex virus هو
+
+5
+00:00:27,050 --> 00:00:33,660
+أشهر فيروس يصيب العين، يعني البرامج الأخرى تصيب
+
+6
+00:00:33,660 --> 00:00:37,520
+العين لكن الـ herpes simplex احنا حسب تجربة الإكلينيكية
+
+7
+00:00:37,520 --> 00:00:44,320
+بتاعتنا أنه يصيب العين بصورة أكثر يعني تكررًا حقيقة
+
+8
+00:00:44,320 --> 00:00:51,940
+هو double strand DNA يعني خلينا نتفق على أن كل
+
+9
+00:00:51,940 --> 00:00:56,640
+الأسرة هذه تحت الـ herpes كلها DNA و double strand
+
+10
+00:00:56,640 --> 00:01:04,850
+فهو شبه باقي العيلة Double strand DNA حجمه كبير 150
+
+11
+00:01:04,850 --> 00:01:10,190
+-200 nano متر متعدد
+
+12
+00:01:10,190 --> 00:01:13,870
+الأوجه تقريبًا
+
+13
+00:01:13,870 --> 00:01:19,250
+متشابه أنا
+
+14
+00:01:19,250 --> 00:01:25,550
+عندي حاجتين نوعين النوع الأول one والنوع الثاني
+
+15
+00:01:25,550 --> 00:01:30,420
+two أنا عندي herpes simplex one و herpes 
+
+16
+00:01:30,420 --> 00:01:35,380
+simplex 2 الـ herpes
+
+17
+00:01:35,380 --> 00:01:40,380
+simplex one هو الذي يختص بقرنية العين أو بالعين
+
+18
+00:01:40,380 --> 00:01:46,920
+يختص بالعين عشان اسمه keratitis human يعني يصيب
+
+19
+00:01:46,920 --> 00:01:51,100
+اللي هو قرنية العين ويصيب الشفايف herpes labiatis
+
+20
+00:01:51,100 --> 00:01:54,360
+يعني بيعمل التهاب الشفتين و التهاب القرنية
+
+21
+00:01:54,360 --> 00:01:58,940
+keratitis  الـ herpes simplex 2 هي هيربس السيمبليكس
+
+22
+00:01:58,940 --> 00:02:02,640
+genitalis يعني ويصيب الأعضاء التناسلية يبقى فيه
+
+23
+00:02:02,640 --> 00:02:06,160
+هيربس سيمبليكس one وهيربس سيمبليكس two لما أقول one
+
+24
+00:02:06,160 --> 00:02:09,940
+يعني للشفة في العين ولما أقول هيربس سيمبليكس two
+
+25
+00:02:09,940 --> 00:02:17,140
+يعني للجهاز التناسلي في الذكاء العلمي بقول
+
+26
+00:02:17,140 --> 00:02:23,340
+أنه يعني في ميول لهذا أن يصيب الـ genital
+
+27
+00:02:23,340 --> 00:02:30,220
+regions يعني الأعضاء التناسلية، اه لكن ممكن أن
+
+28
+00:02:30,220 --> 00:02:34,040
+يُؤخذ من الأعضاء التناسلية على العين ويصيب العين
+
+29
+00:02:34,040 --> 00:02:38,460
+يبقى اللي احنا بنقوله أن اللي من العين غالبًا
+
+30
+00:02:38,460 --> 00:02:40,660
+لا يصيب الأعضاء التناسلية لكن اللي من أعضاء
+
+31
+00:02:40,660 --> 00:02:45,960
+التناسلية ممكن يصيب العين وهذا سنشاهده قدام شوية
+
+32
+00:02:45,960 --> 00:02:49,320
+يبقى هذه الصورة ليه اللي هو الفيروسات تصيب
+
+33
+00:02:49,320 --> 00:02:52,230
+الأعضاء التناسلية هذه الفيروسات تصيب الأعضاء
+
+34
+00:02:52,230 --> 00:02:57,530
+التناسلية في الذكر والأنثى وهذا الـ herpes simplex 
+
+35
+00:02:57,530 --> 00:03:02,630
+مكبر آلاف المرة، طيب إبيدميولوجيا إيش يعني نواحي
+
+36
+00:03:02,630 --> 00:03:06,290
+الوبائية بتاعته؟ بقول الـ herpes simplex infection
+
+37
+00:03:06,290 --> 00:03:10,850
+ممكن تكون في العقليات subclinical subclinical يعني
+
+38
+00:03:10,850 --> 00:03:16,810
+لا تبدو لها أعراض وعلامات بقول
+
+39
+00:03:16,810 --> 00:03:20,750
+أن في الولايات المتحدة الأمريكية في الـ 50 أو 80
+
+40
+00:03:20,750 --> 00:03:24,530
+في المئة من الأشخاص أو المواطنين في الولايات المتحدة
+
+41
+00:03:24,530 --> 00:03:30,670
+الأمريكية مصابون بالـ virus one أو two أو كلاهما
+
+42
+00:03:30,670 --> 00:03:34,470
+ووجدوا
+
+43
+00:03:34,470 --> 00:03:41,320
+أن في دمهم فيه antibodies يعني أجسام مضادة للـ Herpes
+
+44
+00:03:41,320 --> 00:03:48,800
+Simplex في اللي هو سن 30 سنة وفوق سن 30 سنة
+
+45
+00:03:48,800 --> 00:03:53,540
+من الناس، فأنا جاي أصل 30 وانصابوا 80% من
+
+46
+00:03:53,540 --> 00:03:59,780
+المجتمع، هو ممكن أنا أقول أنه يلاقوا في دمهم اللي
+
+47
+00:03:59,780 --> 00:04:04,140
+هو اللي
+
+48
+00:04:04,140 --> 00:04:08,750
+هو Antibodies هذه الـ antibodies اللي جوه الـ serum
+
+49
+00:04:08,750 --> 00:04:14,250
+convention يعني أنه يصل لدم الـ antibodies لجسم
+
+50
+00:04:14,250 --> 00:04:18,670
+المضادة موجودة كثير في الفقراء اللي هو lower
+
+51
+00:04:18,670 --> 00:04:23,230
+socioeconomic groups في الفقراء أكثر من الأغنياء
+
+52
+00:04:23,230 --> 00:04:27,830
+والدول الغير متطورة لأنهم مُتعرّضون كثير للأمراض ومن
+
+53
+00:04:27,830 --> 00:04:34,310
+الفيروسات، حقيقة أن المشكلة، الـ virus هذا يختبئ في
+
+54
+00:04:34,310 --> 00:04:38,590
+الترايجمنال جانجليون في منطقة اسمها Pons الـ virus
+
+55
+00:04:38,590 --> 00:04:38,650
+Pons الـ virus هذا يختبئ في الترايجمنال جانجليون في
+
+56
+00:04:38,650 --> 00:04:38,870
+منطقة اسمها Pons الـ virus هذا يختبئ في الترايجمنال من
+
+57
+00:04:38,870 --> 00:04:39,330
+الجنجليون في منطقة اسمها Pons الـ virus هذا يختبئ في
+
+58
+00:04:39,330 --> 00:04:40,050
+الترايجمنال جانجليون في منطقة اسمها Pons الـ virus
+
+59
+00:04:40,050 --> 00:04:40,910
+هذا يختبئ في الترايجمنال جانجليون في منطقة اسمها
+
+60
+00:04:40,910 --> 00:04:46,250
+Pons الـ virus هذا يختبئ في الترايجمنال جانجليون في
+
+61
+00:04:46,250 --> 00:04:54,610
+منطقة اسمها Pons الـ virus هذا يختبئ في الترايجمنال من
+
+62
+00:04:54,610 --> 00:05:01,390
+الجنجليون في منطقة اسمها Pons 
+
+63
+00:05:02,620 --> 00:05:13,280
+و الـ Medulla Oblongata هنا في اليمين والشمال من الـ brain في
+
+64
+00:05:13,280 --> 00:05:20,900
+اللي هو إيش؟ اللي هو الـ roots بتاعت اللي هو العصب
+
+65
+00:05:20,900 --> 00:05:26,980
+الخامس، وأظن حتى بتأخذ شوية من الـ Pons من عصب
+
+66
+00:05:26,980 --> 00:05:32,880
+الخامس بتخلع العصب هيك المهم أن الـ virus هذا يختبئ
+
+67
+00:05:32,880 --> 00:05:38,500
+في اللي هو الـ midbrain أو في الـ Pons في النواة
+
+68
+00:05:38,500 --> 00:05:43,740
+Trigeminal Ganglion ولمّا الإنسان يضعف بيمشي مع
+
+69
+00:05:43,740 --> 00:05:48,880
+الشيط بتاع العصب وجروح القرنية وجروح على اللي هو
+
+70
+00:05:48,880 --> 00:05:54,600
+الـ lips وين اللي هو Phalmic nerve هو الـ Trigeminal
+
+71
+00:05:54,600 --> 00:05:59,670
+nerve اللي له ثلاث فروع، اللي هو فرع اسمه ophthalmic
+
+72
+00:05:59,670 --> 00:06:05,170
+وفرع اسمه maxillary وفرع اسمه mandibular nerve فالـ
+
+73
+00:06:05,170 --> 00:06:09,990
+ophthalmic nerve هذا هو اللي بيغذي القرنية وبيغذي
+
+74
+00:06:09,990 --> 00:06:16,490
+lips اللي هو الشفايف لما
+
+75
+00:06:16,490 --> 00:06:21,370
+ينتهي الـ infection أو بيأخذ علاج الـ virus بيهرب
+
+76
+00:06:21,370 --> 00:06:27,890
+وين ثاني ويختبئ في المخفي الـ Pons هنا يختبئ أو في
+
+77
+00:06:27,890 --> 00:06:32,070
+الـ midbrain يختبئ لما يضعف ويسبّبه مثلًا أي ضعف
+
+78
+00:06:32,070 --> 00:06:34,990
+مناعي، بعوض ينزل ويصيب القرنية عشان إنكم تلاقوا أن
+
+79
+00:06:34,990 --> 00:06:40,210
+مرض القرنية بالفيروس herpes simplex هنا كثير أنه
+
+80
+00:06:40,210 --> 00:06:48,670
+يتكرر كل ما يفُلِز أو كل ما يسببه ضعف مناعي، طيب
+
+81
+00:06:48,670 --> 00:06:52,990
+بقول أن الإنسان
+
+82
+00:06:53,890 --> 00:06:57,050
+ممكن أن يصيبه ضعف المناعة ويتكرر الـ herpes
+
+83
+00:06:57,050 --> 00:07:00,850
+simplex infection خاصة في مرضى الـ AIDS يعني الـ
+
+84
+00:07:00,850 --> 00:07:07,230
+AIDS بعطي فرصة للميكروبات opportunistic بيقولوا
+
+85
+00:07:07,230 --> 00:07:11,150
+عنها الانتهازية أنها تأخذ الجسم حتى لما تكون لو
+
+86
+00:07:11,150 --> 00:07:15,710
+كانت commensal بتصير aggressive وبتصير يعني قادرة
+
+87
+00:07:15,710 --> 00:07:18,790
+على أن تُفتك بالإنْسان، فالانسان اللي عنده الـ AIDS
+
+88
+00:07:18,790 --> 00:07:23,380
+ممكن جدًا الـ viruses هذه يتكرر عنده بتصير more
+
+89
+00:07:23,380 --> 00:07:30,720
+frequent أنه تجيه كثير، بقولنا احنا الـ herpes
+
+90
+00:07:30,720 --> 00:07:37,480
+simplex 2 اللي يصيب الأعضاء التناسلية بيكون
+
+91
+00:07:37,480 --> 00:07:41,140
+عنده resistance أنه يصيب الـ herpes simplex 1 يعني
+
+92
+00:07:41,140 --> 00:07:44,900
+لما الواحد ينصاب في أحشائه في المناطق التناسلية
+
+93
+00:07:44,900 --> 00:07:52,360
+صعب يعني أنه يصيب المنطقة هذه بـ Simplex one خلاص
+
+94
+00:07:52,360 --> 00:07:58,420
+الـ two بس مُفَكِّر عليه، لكن الـ الـ الـ one ما بسكر على
+
+95
+00:07:58,420 --> 00:08:01,520
+الـ two يعني ممكن أنه ينصاب من الأعضاء التناسلية
+
+96
+00:08:01,520 --> 00:08:05,240
+على العين لكن مش سهل ينصاب يأخذ من العين ويحط في
+
+97
+00:08:05,240 --> 00:08:10,910
+أعضاء التناسلية يعني لو واحد حق أعضاء تناسلية
+
+98
+00:08:10,910 --> 00:08:14,830
+وحق عين اه ينصاب بالـ herpes simplex 2 كمان، لكن
+
+99
+00:08:14,830 --> 00:08:17,570
+لو أخذ من عينه حق عينه وحق الأعضاء التناسلية
+
+100
+00:08:17,570 --> 00:08:23,130
+ما ينصابش في الأعضاء التناسلية وهذا يعني حاجة بدها
+
+101
+00:08:23,130 --> 00:08:29,610
+بحث علمي ليش هو السبب؟ الـ herpes simplex 1 هذا هو
+
+102
+00:08:29,610 --> 00:08:36,070
+المسؤول عن إصابات العين بكثرة ويقول أن 20% تقريبًا
+
+103
+00:08:36,070 --> 00:08:41,300
+من المرضى ينصابون حتى في stroma بتاعة القرنية
+
+104
+00:08:41,300 --> 00:08:45,960
+وممكن في الـ endothelium يصيبهم عتامة على العين
+
+105
+00:08:45,960 --> 00:08:49,200
+ويصير عينهم opaque خاصة إذا كانت هناك recurrent
+
+106
+00:08:49,200 --> 00:08:53,000
+infection يعني متكررة ممكن يصيبهم stroma
+
+107
+00:08:53,000 --> 00:08:56,740
+الـ keratitis و disciform keratitis يعني التهاب
+
+108
+00:08:56,740 --> 00:09:02,820
+القرنية القرصي وممكن أن يصير عتامة وعمى، طيب إيش هي
+
+109
+00:09:02,820 --> 00:09:06,000
+الـ clinical presentation إيش الأعراض والعلامات
+
+110
+00:09:06,000 --> 00:09:11,860
+نسميها إلى general وإلى ocular general يعني في
+
+111
+00:09:11,860 --> 00:09:15,980
+الجسم كله و ocular في العين بس، طب إيش هي الـ
+
+112
+00:09:15,980 --> 00:09:20,920
+general؟ Gingivitis و stomatitis يعني التهاب اللثة
+
+113
+00:09:20,920 --> 00:09:27,020
+والشفتين اللي بيقولونها labiatis مش بس الشفة، الشفة
+
+114
+00:09:27,020 --> 00:09:35,470
+ومع الشفة إيش اللي هو الشفتين الـ gum يعني أسفل
+
+115
+00:09:35,470 --> 00:09:41,130
+اللثة، pharyngitis التهاب البلعوم rhinitis
+
+116
+00:09:41,130 --> 00:09:44,870
+التهاب الأنف الفيروسي tonsillitis التهاب اللوزتين
+
+117
+00:09:44,870 --> 00:09:51,970
+لأن هم موجودين في الحلقة، طيب هذه الحاجات نسميها
+
+118
+00:09:51,970 --> 00:09:56,630
+general يعني general وprimary و general مصيبة
+
+119
+00:09:56,630 --> 00:10:02,060
+fever سخونة و chills رجفة وميالجيا التهاب اللي
+
+120
+00:10:02,060 --> 00:10:06,220
+هو ألم العضلات و lymphadenopathy التهاب أو تضخم
+
+121
+00:10:06,220 --> 00:10:12,860
+للعُقَد الليمفاوية في الرقبة على جانبي الرقبة كمان
+
+122
+00:10:12,860 --> 00:10:19,240
+اللي قولنا lips اللي هتسيبها vesicular eruptions
+
+123
+00:10:19,240 --> 00:10:24,610
+كلمة vesicular يعني حويصلات أو بقع سائلة فزيكل
+
+124
+00:10:24,610 --> 00:10:29,510
+فزيكل يعني زي كيس مائي صغير على الشفايف وكثير
+
+125
+00:10:29,510 --> 00:10:33,670
+من احنا بنسميها بهايها شايفين بيقولوا طلعت له حُمى احنا
+
+126
+00:10:33,670 --> 00:10:37,770
+بيقول الصبح إيش الولد أو البنت هتطلع له حُمى فزيكلر
+
+127
+00:10:37,770 --> 00:10:43,290
+eruption اه on lips ميوكير اه unresolved يعني بتطبخ
+
+128
+00:10:43,290 --> 00:10:46,730
+للاسماء بتطبخ للاسماء، يبقى الست حاجات هذه general
+
+129
+00:10:46,730 --> 00:10:49,450
+أنا ما أركز على الـ general لكن ممكن تجي بالصح
+
+130
+00:10:49,450 --> 00:10:53,750
+والغلط، يعني لكن أركز على الـ ocular إيش primary
+
+131
+00:10:53,750 --> 00:10:57,770
+ocular يعني primary لأول مرة يعني مش هينصاب كثير لأ
+
+132
+00:10:57,770 --> 00:11:03,850
+أول مرة أول مرة فيه follicular keratoconjunctivitis
+
+133
+00:11:03,850 --> 00:11:08,050
+يعني follicles احنا عارفين follicles يعني نُفَقَات
+
+134
+00:11:08,050 --> 00:11:13,810
+صغيرة، بروزات صغيرة على القرنية وعلى الملتحمة، هذه
+
+135
+00:11:13,810 --> 00:11:20,930
+أول شيء ممكن يصيبهم lymphadenitis يعني اكتهاد العقد
+
+136
+00:11:20,930 --> 00:11:26,090
+الليمفاوية على جانب أي رقبة، الشيء الصعب يكون فيه
+
+137
+00:11:26,090 --> 00:11:29,690
+blepharitis يعني لو احنا شفنا حواف
+
+138
+00:11:29,690 --> 00:11:35,690
+الجفن اللي فيه شعر رموش نجيها ملتهبة، الأخطر أنه
+
+139
+00:11:35,690 --> 00:11:38,930
+يصير stromal keratitis يعني قرنية القلصة قرنية
+
+140
+00:11:38,930 --> 00:11:42,930
+القلصة خطيرة جدًا وهذا ما نقول القرحة الشجرية
+
+141
+00:11:42,930 --> 00:11:46,830
+Dendritic ulcer فنشوفها كاملة شوية Dendritic ulcer
+
+142
+00:11:49,530 --> 00:11:54,250
+ذكروا إذن adenitis اللي هو التهاب الغدد الدمعية
+
+143
+00:11:54,250 --> 00:11:58,610
+التهاب الغدد الدمعية الكبرى اللي هي في المحجر من 
+
+144
+00:11:58,610 --> 00:12:05,450
+ناحية الـ upper lateral side احنا حتى الآن بنتكلم 
+
+145
+00:12:05,450 --> 00:12:09,650
+على primary يبقى هذه primary واحد اثنين ثلاثة
+
+146
+00:12:09,650 --> 00:12:17,110
+أربعة خمسة هذه primary الآن ستة مش منهم هذه ستة
+
+147
+00:12:17,110 --> 00:12:24,130
+كتبوها أنه Recurrent Recurrent يعني صارت راحت وجهة
+
+148
+00:12:24,130 --> 00:12:27,290
+راحت وجهة infection يعني مرة جديدة ثلاثة أربعة
+
+149
+00:12:27,290 --> 00:12:30,550
+خلاص ماتت بقول أنا Recurrent infections المتتابعة
+
+150
+00:12:30,550 --> 00:12:34,630
+بصير كون الإبتداء للـ ulcers يعني الإبتداء بتاع
+
+151
+00:12:34,630 --> 00:12:39,310
+القرنية بتقرر وبخش على الـ stroma يعمل interstitial
+
+152
+00:12:39,310 --> 00:12:43,510
+keratitis keratitis في الـ stroma اه اللي اسمه
+
+153
+00:12:43,510 --> 00:12:46,990
+disceform keratitis هذا هو هذا disceform يعني زي
+
+154
+00:12:46,990 --> 00:12:51,770
+الشكل يعني وهذا كيروتايتس وممكن يعمل تلايف وإيه ذو
+
+155
+00:12:51,770 --> 00:12:56,850
+سايكلايتس يدخل على جوا اللي هو الـ iris والـ ciliary
+
+156
+00:12:56,850 --> 00:13:02,050
+body إذا احنا جسمناهم إلى primary general و
+
+157
+00:13:02,050 --> 00:13:10,470
+primary ocular وكمان recurrent
+
+158
+00:13:10,470 --> 00:13:15,910
+يعني ممكن احنا نجسمهم هذه ثلاثة هنعملهم وبعدين
+
+159
+00:13:15,910 --> 00:13:21,380
+نصليحهم هذه ثلاثة recurrent وهذه اثنين primary
+
+160
+00:13:21,380 --> 00:13:27,680
+primary ocular وهذه واحد primary general تكتب 
+
+161
+00:13:27,680 --> 00:13:34,160
+primary general primary general طيب كون الـ
+
+162
+00:13:34,160 --> 00:13:38,680
+isolation هذه اخطر شيء أنه أو أكثر شيء بيصيب
+
+163
+00:13:38,680 --> 00:13:42,460
+الإنسان في الـ virus herpes simplex خاصة one أنه
+
+164
+00:13:42,460 --> 00:13:46,960
+بيقرّف القرنية ومن اخطر الأشياء اللي بتعملها اه 
+
+165
+00:13:46,960 --> 00:13:50,640
+هو common manifestation common manifestation يعني 
+
+166
+00:13:50,640 --> 00:13:56,100
+ظاهرة معتادة أن تصير في الـ herpes simplex virus
+
+167
+00:13:56,100 --> 00:14:01,740
+اه وللأسف أنها recurrent ليش قلنا أن الفيروس مايحس 
+
+168
+00:14:01,740 --> 00:14:06,240
+بقوة مناعة أو بعلاج بيهرب وين في الـ triangle من 
+
+169
+00:14:06,240 --> 00:14:10,320
+الجنجل وفي الـ brain بالتحديد
+
+170
+00:14:10,320 --> 00:14:19,000
+في الـ middle brain والـ pons طيب الآن الـ infection
+
+171
+00:14:19,000 --> 00:14:23,020
+يعتقد
+
+172
+00:14:23,020 --> 00:14:27,920
+أنها بتيجي من العصب خاصة من الفرع الأول ونقصان
+
+173
+00:14:27,920 --> 00:14:31,520
+مكنير بتاع الـ Trigeminal اللي بيغذي القرنية
+
+174
+00:14:31,520 --> 00:14:35,320
+والشفايف بيغذي القرنية والشفايف الـ prognosis
+
+175
+00:14:35,320 --> 00:14:39,640
+المقال والمصير لأسف على الـ vision يعني غالبا
+
+176
+00:14:39,640 --> 00:14:44,240
+هدولة بيؤدي إلى تعتيم القرنية ويصير very poor
+
+177
+00:14:44,240 --> 00:14:50,340
+vision خاصة مع تأخر التشخيص والعلاج يعني اللي
+
+178
+00:14:50,340 --> 00:14:54,560
+بيجينا على طبيب العيون من أولها بنحط الفلوريسين
+
+179
+00:14:54,560 --> 00:14:58,940
+وبين الخضار هذا اسمها Dendritic Ulcer على طول احنا
+
+180
+00:14:58,940 --> 00:15:02,960
+نعطيه زوبراكس نعطيه حاجات مضادة الفيروسات انتفيروس
+
+181
+00:15:02,960 --> 00:15:08,060
+ممكن يشفى خلال أسبوع أو أسبوعين لكن للأسف أن في
+
+182
+00:15:08,060 --> 00:15:12,140
+كتير من الناس delayed diagnosis يصير يروح يعني إلى
+
+183
+00:15:12,140 --> 00:15:16,410
+واحد ما يعرفش يشخص يصير مش عارف أن هذا فيروس ممكن 
+
+184
+00:15:16,410 --> 00:15:19,670
+يعطيه antibiotic أو أي حاجة والفيروس مايكترش فيه 
+
+185
+00:15:19,670 --> 00:15:23,070
+الـ antibiotic وممكن يعمل destruction of the
+
+186
+00:15:23,070 --> 00:15:25,890
+cornea rapid destruction of the cornea خش من
+
+187
+00:15:25,890 --> 00:15:29,030
+الـ epithelium ومن الـ stroma ومن الـ stroma يخش على
+
+188
+00:15:29,030 --> 00:15:36,430
+اللي هو الداخل العين يعمل iridocyclitis طيب الـ
+
+189
+00:15:36,430 --> 00:15:44,460
+corneal disease بتاعة الـ herpes simplex في ثلاث مناطق
+
+190
+00:15:44,460 --> 00:15:48,060
+المنطقة الخارجية Epithelium of the cornea المنطقة 
+
+191
+00:15:48,060 --> 00:15:50,860
+الوسطى Stroma of the cornea المنطقة الداخلية
+
+192
+00:15:50,860 --> 00:15:54,020
+Endothelium of the cornea احنا عارفين طبقات القرنية
+
+193
+00:15:54,020 --> 00:16:00,500
+الخمسة ماهي طبقات القرنية الخمسة Epithelium
+
+194
+00:16:00,500 --> 00:16:06,060
+Bowman's membrane Stroma Descemet's membrane Endothelium
+
+195
+00:16:06,060 --> 00:16:12,990
+مظبوط هكذا بيصيبها Latent Infection يعني عدوى
+
+196
+00:16:12,990 --> 00:16:17,270
+مضيبة للـ herpes simplex وهذا بتعمل Dendritic Ulcer اللي
+
+197
+00:16:17,270 --> 00:16:20,410
+شوفناه احنا الآن هدف الصحيح هذا اسمه Dendritic
+
+198
+00:16:20,410 --> 00:16:24,070
+Ulcer القرحة الشجرية وهذه المميزة بتتكسف
+
+199
+00:16:24,070 --> 00:16:29,850
+بفلوريسين طب إذا لم تعالج هذه أو تأخرت أساسا
+
+200
+00:16:29,850 --> 00:16:33,930
+والعلاج بتخش ع الـ stroma وبتبدأ تحطم الـ stroma
+
+201
+00:16:33,930 --> 00:16:38,570
+وتعمل Opacification Opacification Opacification هي تعتيم
+
+202
+00:16:38,570 --> 00:16:45,750
+للقرنية والـ Disk Form Stroma اللي هو Opacification وهذا
+
+203
+00:16:45,750 --> 00:16:49,050
+طبعا ناتج عن الـ Antigen Antibody يعني في معركة 
+
+204
+00:16:49,050 --> 00:16:55,770
+بين خلايا الليمفاوية وبين الفيروس بنتج عنها Antigen 
+
+205
+00:16:55,770 --> 00:17:00,070
+Antibody Complement وهذا الـ complement بيرسب في 
+
+206
+00:17:00,070 --> 00:17:05,430
+الـ Stroma وبيعمل لي Opacification طب الـ endothelium لو
+
+207
+00:17:05,430 --> 00:17:08,510
+كان الإنسان ضعيف والقرنية عندي ضعيفة وهزمت
+
+208
+00:17:08,510 --> 00:17:12,910
+تدخل على الـ endothelium آخر طبقة داخل القرنية تسمى
+
+209
+00:17:12,910 --> 00:17:17,630
+الـ endotheliitis تبدأ بخلايا الـ endothelium وهذا خطير
+
+210
+00:17:17,630 --> 00:17:28,630
+جدا لأن الـ endothelium يمنع تكون السائل في طبقات 
+
+211
+00:17:28,630 --> 00:17:35,860
+القرنية اللي بيعمل الـ pumping out mechanism يعني 
+
+212
+00:17:35,860 --> 00:17:39,700
+بيطرد هو الـ aqueous من القرنية إلى الخلف في الـ
+
+213
+00:17:39,700 --> 00:17:44,180
+anterior chamber فلما يصير Endotheliitis يعني بيعجز
+
+214
+00:17:44,180 --> 00:17:49,180
+اللي بيصير القرنية بتبكي وبتصير تبت ومليانة بيك
+
+215
+00:17:49,180 --> 00:17:53,380
+بالسوائل بقول
+
+216
+00:17:53,380 --> 00:17:56,780
+أن هذا غالبا اللي بيعمله النوع الأول هربس simplex
+
+217
+00:17:56,780 --> 00:18:04,280
+one اه قدرة الفيروس الجينية يعني الفيروس مرات 
+
+218
+00:18:04,280 --> 00:18:08,140
+بيكون قوي جدا وعدده كبير يخترق إلى داخل العين
+
+219
+00:18:08,140 --> 00:18:12,640
+الـ endotheliitis ومرات بيكون قوي مناعيا اللي هو
+
+220
+00:18:12,640 --> 00:18:17,020
+المريض وبتعالج بدري بيجي find النوع الأول في
+
+221
+00:18:17,020 --> 00:18:20,360
+الـ episclera مابدخلش لـ stroma ولا بدخل على
+
+222
+00:18:20,360 --> 00:18:27,220
+الـ endothelium High Disc Form اللي هو endotheliitis 
+
+223
+00:18:27,880 --> 00:18:31,020
+شايفين ومبين في اسم الإسلام كيف لكن هذا هيعمل 
+
+224
+00:18:31,020 --> 00:18:37,200
+اعتامة ومش هيخلّي الواحد يشوف يعني بصره كويس طيب
+
+225
+00:18:37,200 --> 00:18:41,800
+لو قلنا إنسان كان ضعيف بيصيبه اللي هو إيه إيش
+
+226
+00:18:41,800 --> 00:18:46,760
+Iritis herpes simplex iritis يعني التهاب قزحية
+
+227
+00:18:46,760 --> 00:18:52,340
+الفيروسي نوعين Granulomatous و Non-Granulomatous
+
+228
+00:18:52,340 --> 00:18:57,460
+من Granuloma لو ترسب في اللي هو خلايا الدم البيضاء
+
+229
+00:18:57,460 --> 00:19:02,440
+على الـ endothelium من الخلف ثم Keratic Precipitates
+
+230
+00:19:02,440 --> 00:19:08,100
+Precipitates يعني خلايا مترسبة على الـ endothelium بتاع
+
+231
+00:19:08,100 --> 00:19:11,100
+القرنية وده أنا في الست سنين بحكي بريكوا معاها
+
+232
+00:19:11,100 --> 00:19:17,020
+الآن وممكن تترسب كمان على الـ iris في الـ ciliary body
+
+233
+00:19:17,020 --> 00:19:23,980
+وعلى الـ trabeculum شوفناها ترابكيولايتس كمان إذا
+
+234
+00:19:23,980 --> 00:19:26,980
+كان عمل ترابكيولايتس في الـ Angle of anterior
+
+235
+00:19:26,980 --> 00:19:30,480
+chamber ممكن ترفع ضغط العين وتعمل بلوكوما وتصبح
+
+236
+00:19:30,480 --> 00:19:35,080
+Intraocular Pressure يبقى هذه الصورة هيها هذه اسمها 
+
+237
+00:19:35,080 --> 00:19:39,260
+Granulomatous ليش؟ لأنه في الخلايا هذه خلف
+
+238
+00:19:39,260 --> 00:19:43,140
+البيضاء هذه خلف الـ endothelium اسمها Granulomatous
+
+239
+00:19:43,140 --> 00:19:47,480
+هيها خلف القرنية نشوفها احنا بيضاء لونها كبيرة في
+
+240
+00:19:47,480 --> 00:19:52,930
+الحجم طيب النوع الثاني Non-Granulomatous هذه ليست 
+
+241
+00:19:52,930 --> 00:19:57,610
+Keratic Precipitates بدون Keratic Precipitates على
+
+242
+00:19:57,610 --> 00:20:01,010
+الـ endothelium وغالبا هذا يحدث في الـ endothelium
+
+243
+00:20:01,010 --> 00:20:09,050
+الـ endothelium اللي هو الضعفاء مناعيا فبتلاقي فيهم
+
+244
+00:20:09,050 --> 00:20:16,950
+حمرة ومؤلمة وفيه دمع كتير من الـ iridocyclitis وفيه 
+
+245
+00:20:16,950 --> 00:20:20,940
+blurred vision مش هيبص كويس وفيه Miosis الـ Miosis
+
+246
+00:20:20,940 --> 00:20:26,640
+النتيجة أن الـ ciliary muscle بتاعتها بتضيق بسبب الـ virus
+
+247
+00:20:26,640 --> 00:20:33,940
+عند Miosis حماية العين تلاقي فيه pinhole pupil pin
+
+248
+00:20:33,940 --> 00:20:39,640
+hole pupil cells and flare موجودين في الآخرة المر
+
+249
+00:20:39,640 --> 00:20:48,800
+وفي يعني زي خلايا عاملة نوع من التعرّك وهنا ممكن
+
+250
+00:20:48,800 --> 00:20:56,120
+تعمل Hypopyon مثل صديد يعني Hypopyon وين Hypopyon 
+
+251
+00:20:56,120 --> 00:21:01,700
+فيه Hypopyon بتكون عامل صديد هيه هذا الأبيض
+
+252
+00:21:01,700 --> 00:21:08,500
+Hypopyon يبقى أنه لو كان المريض يعني شيخ كبير و
+
+253
+00:21:08,850 --> 00:21:13,870
+ومناعيا مش كويس بيعملوا النوع ده Granulomatous
+
+254
+00:21:13,870 --> 00:21:16,970
+وHypopyon يعني كان قوي مناعيا بس بيعملوا
+
+255
+00:21:16,970 --> 00:21:23,890
+Granulomatous وشفاء أكثر طيب لو إنسان ضعيف أكثر زي
+
+256
+00:21:23,890 --> 00:21:26,870
+مرضى الـ AIDS بيعملوا Retinitis herpes simplex 
+
+257
+00:21:26,870 --> 00:21:31,170
+Retinitis يعني وصل للشبكية في الـ
+
+258
+00:21:31,170 --> 00:21:36,160
+immunosuppressed بيروح على الشبكية invade يعني
+
+259
+00:21:36,160 --> 00:21:41,340
+بيغزو الشبكية directly بسرعة وبيعمل Choroiditis
+
+260
+00:21:41,340 --> 00:21:45,520
+وRetinitis Choroiditis وRetinitis وVitritis التهاب
+
+261
+00:21:45,520 --> 00:21:54,100
+اللي هو السائل الزجاجي وممكن اللي هو يصيب اللي هو
+
+262
+00:21:54,100 --> 00:21:58,800
+الشرعين بتاعة الشبكية ممكن يعمل في الشبكية 
+
+263
+00:21:58,800 --> 00:22:04,390
+Hemorrhage هو الـ Hemorrhage هذا لما يشف اللي هو
+
+264
+00:22:04,390 --> 00:22:08,410
+الدم فع الشبكية بيبقى مكان الـ scar يعني يعمل
+
+265
+00:22:08,410 --> 00:22:13,330
+تلايف ويعمل أطر فكرتنا أطر فكرتنا يعني أن الشبكية
+
+266
+00:22:13,330 --> 00:22:20,230
+تصير إيش متلايفة المهم طبعا هذا بيعتمد على النواحي
+
+267
+00:22:20,230 --> 00:22:27,710
+المنعية عند الإنسان طيب نرجع لحديثنا أخطر طبعا شيء 
+
+268
+00:22:27,710 --> 00:22:29,050
+أنه يسيبها الـ herpes
+
+269
+00:22:31,960 --> 00:22:39,440
+بقول لي الـ Retinitis هاني نوعين Congenital وأبطل
+
+270
+00:22:39,440 --> 00:22:45,000
+Congenital يعني لحديث الولادة حديث الولادة أثناء 
+
+271
+00:22:45,000 --> 00:22:50,100
+نزوله في قناة الولادة خاصة عنق الرحم اللي مصاب
+
+272
+00:22:50,100 --> 00:22:54,080
+بالأنسة الحامل herpes simplex to وقلنا هذا herpes
+
+273
+00:22:54,080 --> 00:22:57,900
+simplex to بينزل برأسه ويعني بياخدوا الـ virus 
+
+274
+00:22:57,900 --> 00:23:03,100
+during delivery أثناء الوضع الولادة يعني وهذا
+
+275
+00:23:03,100 --> 00:23:07,040
+بياخده في عينيه وبيصيبه بيكون ضعيف ممكن يصيبه
+
+276
+00:23:07,040 --> 00:23:14,000
+Keratitis وIridocyclitis ويصيبه إيش في عينيه يبقى
+
+277
+00:23:14,000 --> 00:23:18,180
+اسمه Neonatal Keratitis Neonatal حديثي الولادة
+
+278
+00:23:18,180 --> 00:23:23,040
+التهاب الشبكية حديثي الولادة الفيروسي هذا هذا اللي
+
+279
+00:23:23,040 --> 00:23:27,240
+بيعمل الـ tone لأن الأم صابع في أعضائها التناسلية
+
+280
+00:23:27,240 --> 00:23:30,160
+خاصة في الرحم والمهبل طيب 
+
+281
+00:23:33,080 --> 00:23:36,800
+أما اللي بيصيب الـ adults غالبا هربس الـ next one
+
+282
+00:23:36,800 --> 00:23:44,540
+يعني من واحد لواحد من عين لعين يعني خاصة إن واحد
+
+283
+00:23:44,540 --> 00:23:49,940
+حك عينه وسلم على واحد حك عينه هذا اللي سلم عليه 
+
+284
+00:23:49,940 --> 00:23:55,000
+صابه في الشبكة بتاعته فالناس اللي ضعيفين مناعيا
+
+285
+00:23:55,000 --> 00:23:59,380
+immunosuppressed patients is rapidly progressive
+
+286
+00:23:59,380 --> 00:24:03,020
+يعني تتقدم بسرعة في عينيه تنتهي بيلاترال انفكشن في
+
+287
+00:24:03,020 --> 00:24:07,300
+عينيه التنين وممكن حتى تظهر إنكفالايتس fatal
+
+288
+00:24:07,300 --> 00:24:10,540
+encephalitis لأن الشبكية تمشي الفيروس مع العصب
+
+289
+00:24:10,540 --> 00:24:14,800
+البصري of تكناب ويروح على المخ وممكن يعمل fatal
+
+290
+00:24:14,800 --> 00:24:21,360
+encephalitis يعني الجهاب اللي هو المخ المميت طيب
+
+291
+00:24:21,360 --> 00:24:25,540
+ايش اللي عنده Retinitis بيشكي بدينا ايش علاله ايش
+
+292
+00:24:25,540 --> 00:24:29,350
+علاماته يا ربيعلمات و أعراض الـ clinical picture
+
+293
+00:24:29,350 --> 00:24:35,750
+blood pressure في الأول يعني مغبش بعدين نفحص
+
+294
+00:24:35,750 --> 00:24:40,510
+أسلّتنا بنلاقي اللي هو الانتيروي سيجمنت فيها
+
+295
+00:24:40,510 --> 00:24:45,130
+inflammation الـ inflammation هذا جاي من الريدو
+
+296
+00:24:45,130 --> 00:24:49,270
+سايكليتس والسيريدس فازم الريدو سايكليتس أو ال
+
+297
+00:24:49,270 --> 00:24:54,660
+ايريتس يعني وصل القذحية الـ فيروس ممكن أن يظهر
+
+298
+00:24:54,660 --> 00:24:58,740
+الشبكية ونصر الشبكية ونشوف الشبكية حال دا جهها
+
+299
+00:24:58,740 --> 00:25:04,740
+إيديمة متورمة متفيخة وفي عليها hemorrhage يعني
+
+300
+00:25:04,740 --> 00:25:09,800
+عليها دم وممكن ونغلق الشرايين 
+
+301
+00:25:14,820 --> 00:25:18,880
+بعدين نفحص على الـ retina بيجينا ايرايتس وبعدين
+
+302
+00:25:18,880 --> 00:25:24,880
+نوسع الـ pupil ونعمل retina يعني فحص لجناها
+
+303
+00:25:24,880 --> 00:25:28,500
+الهيموتاس الهيمة وفيها الهيموتاس الهيموتاس
+
+304
+00:25:28,500 --> 00:25:29,560
+الهيموتاس الهيموتاس الهيموتاس الهيموتاس الهيموتاس
+
+305
+00:25:29,560 --> 00:25:30,400
+الهيموتاس الهيموتاس الهيموتاس الهيموتاس الهيموتاس
+
+306
+00:25:30,400 --> 00:25:30,600
+الهيموتاس الهيموتاس الهيموتاس الهيموتاس الهيموتاس
+
+307
+00:25:30,600 --> 00:25:33,100
+الهيموتس الهيموتس الهيموتس الهيموتس الهيموتس
+
+308
+00:25:33,100 --> 00:25:38,240
+الهيموتس الهيموتس الهيموتس الهيموتس الهيموتس
+
+309
+00:25:38,240 --> 00:25:43,110
+الهيموتس الهيمأه symptoms and signs هذي clinical
+
+310
+00:25:43,110 --> 00:25:47,970
+الـ diagnoses المخبري للـ herpes simplex virus طبعا
+
+311
+00:25:47,970 --> 00:25:53,890
+إلا ما نحك بطنه ونحك شفاته أو شفايفه هو يعمل
+
+312
+00:25:53,890 --> 00:25:59,590
+viral culture في المزارع الفيروسية مزارع الفيروسية
+
+313
+00:25:59,590 --> 00:26:04,710
+هذا مش عليكم وهذا مش عليكم بس بتقوليلي ايه في
+
+314
+00:26:04,710 --> 00:26:11,470
+viral culture طبعا يعني أنا شايف إنه احنا هيك بلغنا
+
+315
+00:26:11,470 --> 00:26:15,470
+نهاية هذا البروز herpes simplex 1 و2 واسأل الله
+
+316
+00:26:15,470 --> 00:26:20,830
+سبحانه وتعالى إنه يعني ينفع يعني بهذه المحاضرة لأن
+
+317
+00:26:20,830 --> 00:26:25,510
+هذا أكثر شيء بيصيب القرانية الـ herpes simplex
+
+318
+00:26:25,510 --> 00:26:29,310
+تحياتي لكوا في نهاية المحاضرة الثلاثين يعني فضلنا
+
+319
+00:26:29,310 --> 00:26:33,510
+حوالي محاضرة أو تلاتة وبنخلص بالسلامة إن شاء الله
+
+320
+00:26:33,510 --> 00:26:34,490
+السلام عليكم
diff --git a/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/MQ4RtaEQjtc.srt b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/MQ4RtaEQjtc.srt
new file mode 100644
index 0000000000000000000000000000000000000000..e8460a1d4742cf0f7e4da1ea2e6951dd4f2828fa
--- /dev/null
+++ b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/MQ4RtaEQjtc.srt
@@ -0,0 +1,1672 @@
+1
+00:00:00,000 --> 00:00:04,340
+اعوذ بالله من الشيطان الرجيم بسم الله الرحمن الرحيم
+
+2
+00:00:04,340 --> 00:00:08,360
+الحمد لله رب العالمين و أصلي و أسلم على النبي المصطفى
+
+3
+00:00:08,360 --> 00:00:15,060
+بناتي في المستوى الثالث في قسم البصريات 
+مساء الخير
+
+4
+00:00:15,060 --> 00:00:19,920
+أحياء دقيقة أبدأ
+
+5
+00:00:19,920 --> 00:00:24,030
+معكم في المحاضرة الرابعة والعشرين وهذه لعلها تكون
+
+6
+00:00:24,030 --> 00:00:30,570
+أهم محاضرة في هذه السلسلة الأخيرة من محاضرات تتعلق
+
+7
+00:00:30,570 --> 00:00:37,310
+بالـ bacterial keratitis يعني التهاب القرنية
+
+8
+00:00:37,310 --> 00:00:41,810
+البكتيري و تقرحات القرنية الناجمة عنها يبقى 
+
+9
+00:00:41,810 --> 00:00:45,890
+ulceration تقرحات و keratitis التهاب القرنية حقيقة
+
+10
+00:00:45,890 --> 00:00:51,050
+كما أنا قلت أو أضفت أن هذه تكون أهم محاضرة هي و
+
+11
+00:00:51,050 --> 00:00:55,580
+لبعضها في هذا الموضوع اللي بيقول إن البكتيريا
+
+12
+00:00:55,580 --> 00:01:07,460
+keratitis والقرنيه الاصر او الإصراشن هذا الموضوع بيجي
+
+13
+00:01:07,460 --> 00:01:12,280
+من وين يعني من بكتيريا شرسة دي جدا بتكون عايشة في
+
+14
+00:01:12,280 --> 00:01:16,760
+الملتحمة وممكن في الـ eyelid margin يبقى من وين
+
+15
+00:01:16,760 --> 00:01:22,910
+بتجيب البكتيريا بيجي من الملتحمة ومن حواف الجفون
+
+16
+00:01:22,910 --> 00:01:27,510
+مثال على ذلك النيسيريا الجونوريا النيسيريا الجونوريا
+
+17
+00:01:27,510 --> 00:01:31,710
+اللي بتعمل مرض السيلان واتكلمنا عنها قبل ذلك أكثر
+
+18
+00:01:31,710 --> 00:01:38,610
+من مرة النيسيريا الجونوريا أحد البكتيريا اللي يعني
+
+19
+00:01:38,610 --> 00:01:42,790
+تؤدي إلى ulcerative keratitis الى تقرح  مش كل بكتيريا
+
+20
+00:01:42,790 --> 00:01:47,030
+بتعمل ulcer في بكتيريا بتعمل كيراتايتس بس على
+
+21
+00:01:47,030 --> 00:01:51,710
+السطح لكن اللي بتعمل ulcer يعني داخل تحت
+
+22
+00:01:52,930 --> 00:01:57,330
+الابيثيليوم وصلت لبعوما مبرين وممكن تكون وصلت لـ
+
+23
+00:01:57,330 --> 00:02:04,230
+stroma of the cornea تقول إن الـ majority of cornea
+
+24
+00:02:04,230 --> 00:02:08,810
+الأساس الغالبية الأعظم من هذه التقرحات القرنية
+
+25
+00:02:08,810 --> 00:02:13,770
+تالي injury of the cornea ابيثيليوم ليش injury of the
+
+26
+00:02:13,770 --> 00:02:18,910
+cornea ابيثيليوم اللي هو نوع من تجريح للطبقة
+
+27
+00:02:18,910 --> 00:02:23,600
+الطلائية اللي هي بتغطي القرنية يعني فتحنا الباب
+
+28
+00:02:23,600 --> 00:02:29,820
+يعني مثلا هنا قرنية فيها ابيثيليوم هيك إجا شيء 
+
+29
+00:02:29,820 --> 00:02:35,840
+خبشه شل هذه المنطقة هذه المنطقة صارت من دون غطاء
+
+30
+00:02:36,790 --> 00:02:40,610
+البكتيريا اللي في الملتحمة واللي في الـ eyelid واللي
+
+31
+00:02:40,610 --> 00:02:46,910
+في السقف بتاع القرنية وكتابة بتلاقي باب زي
+
+32
+00:02:46,910 --> 00:02:50,990
+اللي بفتح باب الحرامي الحرامي اللي يجيب باب مفتوح
+
+33
+00:02:50,990 --> 00:02:56,230
+يدخل منه طيب ما هي العوامل المساعدة predisposing
+
+34
+00:02:56,230 --> 00:03:00,730
+factors كتيرة بس إحنا هناخد الـ common منها العوامل
+
+35
+00:03:00,730 --> 00:03:06,920
+مساعدة لحدوث البكتيريا كيراتايتس والـ corneal ulcer
+
+36
+00:03:06,920 --> 00:03:12,380
+أولها الـ contact lens use استعمال عدسات  الاصرة
+
+37
+00:03:12,380 --> 00:03:18,300
+الكثير من عدسات الاصرة قد تكون ملوثة أو قد بساء 
+
+38
+00:03:18,300 --> 00:03:25,800
+استعمالها أو قد يصير تقصير في تطهيرها دوريًا وهذه 
+
+39
+00:03:25,800 --> 00:03:31,300
+أحد منعات التهاب القرنية وتقرح القرنية accidental
+
+40
+00:03:31,300 --> 00:03:38,060
+cornea abrasion accidental بالصدفة يعني واحد
+
+41
+00:03:38,060 --> 00:03:43,640
+يعني بيحط عصا خشبية بيدفعها جرح القرنية فهذا
+
+42
+00:03:43,640 --> 00:03:49,500
+accidental مثلا ولد صغير بيلعب
+
+43
+00:03:49,500 --> 00:03:55,560
+ولد صغير يعني أي آلة حادة هيك راح طرف عينه راح 
+
+44
+00:03:55,560 --> 00:04:01,130
+خبشها أو بيدفع خبشها ممكن جدا إن إنسان فينا يتعرض
+
+45
+00:04:01,130 --> 00:04:09,710
+لحاجات كتيرة إن تؤدي إلى خربشة في الابيثيليوم وهذا
+
+46
+00:04:09,710 --> 00:04:13,380
+فتحنا الباب للبكتيريا إن البكتيريا موجودة فيش واحد 
+
+47
+00:04:13,380 --> 00:04:17,360
+بيقول إن العين معقمة يعني بيحسب إن سطح العين معقم 
+
+48
+00:04:17,360 --> 00:04:22,200
+بيكون غلطان في العشرات من البكتيريا والفيروسات 
+
+49
+00:04:22,200 --> 00:04:26,240
+وربما كانت أخرى عايشة بتتغذى على سطح القرنية بس 
+
+50
+00:04:26,240 --> 00:04:30,120
+commensal commensal يعني إيش متعايشة اللي جت الباب
+
+51
+00:04:30,120 --> 00:04:37,400
+مفتوح يعني اللي جت مثلا هيك فتحة راح تخش منها فورًا
+
+52
+00:04:37,400 --> 00:04:42,830
+مش هتستنى طيب trichiasis طبعا إحنا يمكن في ال
+
+53
+00:04:42,830 --> 00:04:49,230
+ايدزز يحطوا trichiasis اللي هو الرموش الحاكّة اللي
+
+54
+00:04:49,230 --> 00:04:55,710
+بتحك زي هذه مثلا trichiasis هذا بيجي بتركيّمات الك
+
+55
+00:04:55,710 --> 00:05:01,890
+تركيّمات بيصير اللي هو الرموش هذه بدل ما هي لبرا زي
+
+56
+00:05:01,890 --> 00:05:05,470
+ما قربنا خرجها هيك زي جرافر فطاقية لبرا بتصير لجوه
+
+57
+00:05:05,470 --> 00:05:11,830
+واتكنّست في سطح القرنية وتجرح فيه وكمان bullous
+
+58
+00:05:11,830 --> 00:05:19,150
+keratopathy هو نوع من الاعتناء القرني يعني اللي 
+
+59
+00:05:19,150 --> 00:05:26,150
+بنفخ الابيثيليوم زي هذه مثلا شايفين كيف هاي هنا زي
+
+60
+00:05:26,150 --> 00:05:33,160
+كيس صغير هيك بتكون على سطح القرنية بيقولوا عنه
+
+61
+00:05:33,160 --> 00:05:42,420
+كيراتوباتي بولص بولص زي يعني كيس مية زي واحد لما 
+
+62
+00:05:42,420 --> 00:05:50,060
+بيبربج بالحرج الجد بيصير فيه يعني بروسه هيتنفخ فيه
+
+63
+00:05:50,060 --> 00:05:55,640
+ميه فهد اسمها بولص كيراتوباتي هذه أحسن جو لأنها
+
+64
+00:05:55,640 --> 00:06:02,180
+ضعيفة إن تدخل البكتيريا خمسة alterations in ocular
+
+65
+00:06:02,180 --> 00:06:06,540
+surface from dry eye إحنا عارفين إن الدموع كتير
+
+66
+00:06:06,540 --> 00:06:10,140
+قلنا فيها defense عن العين وعدّدنا حوالي عشرة أو
+
+67
+00:06:10,140 --> 00:06:16,270
+أكثر من defense mechanisms on the eye surface فلو
+
+68
+00:06:16,270 --> 00:06:20,450
+واحد عنده dry eye بتكون عنده كتير الـ defense هذه
+
+69
+00:06:20,450 --> 00:06:24,750
+ناقصة وبالتالي البكتيريا تتغلب على الـ epithelium
+
+70
+00:06:24,750 --> 00:06:29,150
+متخش منه ستة من العوامل المساعدة chronic
+
+71
+00:06:29,150 --> 00:06:32,910
+blepharitis الناس اللي عندهم التهاب في حواف الجفون
+
+72
+00:06:33,790 --> 00:06:37,210
+كثير في ناس حواف الدفون بتكون عنده حمرة وفيها قشرة
+
+73
+00:06:37,210 --> 00:06:42,370
+دايما فهذه البكتيريا لابد أن تحاول تغزو سطحها
+
+74
+00:06:42,370 --> 00:06:46,610
+القرنية كعمل مساعد diabetes mellitus هو حقيقة مسكين هذا 
+
+75
+00:06:46,610 --> 00:06:51,790
+اللي هو مريض السكري diabetes اسمه آه diabetes mellitus اسم
+
+76
+00:06:51,790 --> 00:06:56,170
+المرض يعني إن كل المناعة بتاعته بتكون subnormal 
+
+77
+00:06:56,170 --> 00:07:01,310
+subnormal يعني أقل من الطبيعي ومنها سطح العين
+
+78
+00:07:01,310 --> 00:07:04,970
+ومنها سطح العين المسكين يعني كل المناعة بتاع الجسم
+
+79
+00:07:04,970 --> 00:07:09,750
+بتكون ضعيفة السكري وإحنا بالمناسبة يعني في مرض 
+
+80
+00:07:09,750 --> 00:07:14,490
+الكورونا الحالي بنخاف على الناس الـ diabetics كتير
+
+81
+00:07:14,490 --> 00:07:18,010
+لأنه لما نسيبهم زي ما نسيب الـ non-diabetics
+
+82
+00:07:19,890 --> 00:07:25,770
+الـ alcoholism يعني الناس مدمني الخمور برضه هذه الخمور
+
+83
+00:07:25,770 --> 00:07:31,350
+لها جثة وبتنزل المناعة كتير وبتساعد على تقرحات سطح 
+
+84
+00:07:31,350 --> 00:07:36,650
+القرنية واخر شيء poor blink reflex يعني إحنا غالبا 
+
+85
+00:07:36,650 --> 00:07:40,510
+إنك تشوف مريع أو مريعة في التلفزيون بتلاقي إنه 
+
+86
+00:07:40,510 --> 00:07:48,050
+خلال دقيقة رمش أقل شيء يمكن عشر مرات برمشتلقائيا و
+
+87
+00:07:48,050 --> 00:07:53,550
+بدون شعور لو راجينا واحد إنه بفتح وبرمش مدة 
+
+88
+00:07:53,550 --> 00:08:00,690
+طويلة هذا أرضى إنه يصيبه تقرحات في القرنية لأن الـ 
+
+89
+00:08:00,690 --> 00:08:08,310
+blink بيقولوا عنها الغمضة هذه بتعمل على يعني إعادة
+
+90
+00:08:08,310 --> 00:08:16,330
+تموضيع وفرد وتوزيع لـ tear film إحنا tear film فيه
+
+91
+00:08:16,330 --> 00:08:20,150
+منه بيروح وفيه منه بيه جديد فلما إحنا نغمض ونفتح
+
+92
+00:08:20,150 --> 00:08:26,050
+يعني زي ما نجيب إحنا يعني مثلث الجبنة ونفتحه
+
+93
+00:08:26,050 --> 00:08:30,310
+بالمعلقة أو بالشوكة نفرّغه على الخبز بيصير مفرون لو 
+
+94
+00:08:30,310 --> 00:08:35,050
+ما حطينا شوكة أو يعني معلقة بيبقى مكّون في النص 
+
+95
+00:08:35,050 --> 00:08:39,450
+وبالتالي صعبانه يغطي المساحة بتاعة الـ sandwich
+
+96
+00:08:39,450 --> 00:08:44,990
+وهكذا الـ blink اللي هو الترميش reflex اسمه مهم جدا
+
+97
+00:08:44,990 --> 00:08:49,950
+يعني واحد عنده واحد أو أكثر من التسعة هدول ممكن 
+
+98
+00:08:49,950 --> 00:08:55,770
+جدا إن يكون a good predisposing factor يعني أو 
+
+99
+00:08:55,770 --> 00:08:59,250
+factors يعني عوامل مساعدة على إحداث
+
+100
+00:08:59,250 --> 00:09:03,090
+البكتيريا كيراتايتس والـ corneal ulceration
+
+101
+00:09:05,450 --> 00:09:12,270
+طيب نتكلم على إنه إيش اللي prognosis على النظر
+
+102
+00:09:12,270 --> 00:09:17,310
+prognosis يعني النتيجة أو المصير أو المقال النتيجة
+
+103
+00:09:17,310 --> 00:09:23,410
+مش diagnosis تشخيص لأ prognosis المقال أو اللي هو
+
+104
+00:09:23,410 --> 00:09:27,690
+النتيجة على الـ visual على الـ vision يعني على الـ
+
+105
+00:09:27,690 --> 00:09:31,110
+vision في حالة في بكتيريا كيروتيتس و corneal
+
+106
+00:09:31,110 --> 00:09:36,540
+ulceration بيقول لي إن في متغيرات بتأثر في الموضوع
+
+107
+00:09:36,540 --> 00:09:40,160
+يعني مش كل الناس زي بعضها الـ variables هذه
+
+108
+00:09:40,160 --> 00:09:44,140
+المتغيرات منها bacterial virulence يعني أنا لما
+
+109
+00:09:44,140 --> 00:09:50,660
+أجيب Staphylococcus aureus وأجيب Staphylococcus epidermidis 
+
+110
+00:09:51,300 --> 00:09:56,280
+طبعا الـ epidermidis هتأكل القرنية لما أجيب أنا
+
+111
+00:09:56,280 --> 00:10:02,380
+Streptococcus pyogenes خطيرة وأجيب Streptococcus
+
+112
+00:10:02,380 --> 00:10:07,560
+viridans لأ الـ viridans ماهي تعمل يعني كل ما كانت
+
+113
+00:10:07,560 --> 00:10:11,980
+الميكروب أو البكتيريا more virulent كل ما كان الـ
+
+114
+00:10:11,980 --> 00:10:18,300
+prognosis bad bad prognosis ليش المعنى bad 
+
+115
+00:10:18,300 --> 00:10:23,880
+prognosis الـ virulent الفيرولاند بكتيريا طب الـ non
+
+116
+00:10:23,880 --> 00:10:30,660
+virulent bacteria لأ تعمل good prognosis
+
+117
+00:10:30,660 --> 00:10:37,520
+يعني المقال على النظر يكون كويس طب host defense
+
+118
+00:10:37,520 --> 00:10:42,940
+طيب اللي هو المناعة بتاعة الشخص ومناعته كله ومناعة
+
+119
+00:10:42,940 --> 00:10:46,980
+عيونه كل ما كانت المناعة قوية كل ما كان good
+
+120
+00:10:46,980 --> 00:10:51,750
+prognosis طب وكل ما كانت المناعة weak إذا ما كنا
+
+121
+00:10:51,750 --> 00:10:53,910
+إذا ما كنا إذا ما كنا إذا ما كنا إذا ما كنا إذا ما
+
+122
+00:10:53,910 --> 00:10:57,630
+كنا إذا ما كنا إذا 
+
+123
+00:10:57,630 --> 00:11:03,990
+ما كنا إذا ما كنا إذا
+
+124
+00:11:03,990 --> 00:11:05,570
+ما كنا إذا ما كنا إذا ما كنا إذا ما كنا إذا ما كنا
+
+125
+00:11:05,570 --> 00:11:05,870
+إذا ما كنا إذا ما كنا إذا ما كنا إذا ما كنا إذا ما
+
+126
+00:11:05,870 --> 00:11:07,390
+كنا إذا ما كنا إذا ما كنا إذا ما كنا إذا ما كنا
+
+127
+00:11:07,390 --> 00:11:07,430
+كنا إذا ما كنا إذا ما كنا إذا ما كنا إذا ما كنا
+
+128
+00:11:07,430 --> 00:11:08,550
+إذا ما كنا إذا ما كنا إذا ما كنا إذا ما كنا إذا ما
+
+129
+00:11:08,550 --> 00:11:11,810
+كنا إذا ما كنا إذا ما كنا إذا ما كنا إذا ما كنا
+
+130
+00:11:11,810 --> 00:11:15,990
+إذا ما 
+
+131
+00:11:15,990 --> 00:11:20,290
+كنا إذا ما بيكون good prognosis يبقى الـ location
+
+132
+00:11:20,290 --> 00:11:25,410
+التموضّع أو المكان اللي بدأ يقول answer primary أنا 
+
+133
+00:11:25,410 --> 00:11:29,490
+كتير مر عليّ لما أكون في الـ periphery بيقول إننا
+
+134
+00:11:29,490 --> 00:11:32,850
+بنعالجها بسلام لأن الـ visual access اسمه
+
+135
+00:11:32,850 --> 00:11:38,330
+هذا clear مش عليه الـ opacity طب effectiveness of
+
+136
+00:11:38,330 --> 00:11:44,800
+treatment آه بروح لـ ... ما تأخذونش طبيب عام يعني حتى
+
+137
+00:11:44,800 --> 00:11:51,380
+لو سبقه وشاف في أسأت أعطاه weak antibiotic ثلاثة
+
+138
+00:11:51,380 --> 00:11:56,520
+أربعة أيام خربت عيونه لكن واحد ثاني راح من أولها
+
+139
+00:11:56,520 --> 00:12:02,360
+للمستشفى العيون أو لطبيب هادق قوي على طول أعطاه أقوى
+
+140
+00:12:02,360 --> 00:12:09,020
+العلاجات فصار effective يبقى فيه تناسب رضى بين 
+
+141
+00:12:09,020 --> 00:12:15,430
+قوة العلاج وبين الـ good prognosis كل ما كان العلاج
+
+142
+00:12:15,430 --> 00:12:20,130
+قويًا كل ما كان البرونوز جيد وكل ما كان العلاج ضعيف
+
+143
+00:12:20,130 --> 00:12:28,930
+أو متأخرًا كل ما كان البرونوز ضعيف طيب 
+
+144
+00:12:28,930 --> 00:12:36,790
+تقول لي ما هي العلامات التي لو وجدها الفاحص
+
+145
+00:12:39,650 --> 00:12:44,130
+يعني في البداية في الـ early stage ممكن جدا يأخذ
+
+146
+00:12:44,130 --> 00:12:49,870
+علاج مجرى أحسن ما هي الـ science الموجودة في
+
+147
+00:12:49,870 --> 00:12:56,910
+البداية والتشخيص فيها بصير سريع وجيد أول شيء لو
+
+148
+00:12:56,910 --> 00:13:02,890
+نظر الفاحص للهيبتيريوم اه هلّاجي فيه نقص في منطقة من 
+
+149
+00:13:02,890 --> 00:13:05,310
+الهيبتيريوم نقص اه
+
+150
+00:13:08,070 --> 00:13:14,390
+طيب لو شاف الـ ulcer يعني يقول لنا هاي القرنية وهي
+
+151
+00:13:14,390 --> 00:13:20,190
+الـ ulcer المنطقة هذه هيك لو شاف الـ base يعني الـ
+
+152
+00:13:20,190 --> 00:13:23,830
+base يعني من ورا هيك الـ base
+
+153
+00:13:27,250 --> 00:13:32,090
+بيشوف degenerating collagen باسم الـ LAMB المنذر
+
+154
+00:13:32,090 --> 00:13:35,870
+and this accumulation of polymorphonucleosis خلايا
+
+155
+00:13:35,870 --> 00:13:40,130
+الدم البيضاء خلايا الدم البيضاء خلايا البارعة اللي
+
+156
+00:13:40,130 --> 00:13:47,030
+بيبعثها الجسم عبر الدم لِتَبتلع الميكروبات فاحنا
+
+157
+00:13:47,030 --> 00:13:51,300
+ساعة ما نشوف الـ ulcer هنلاقي الكولاجين بتاع الـ
+
+158
+00:13:51,300 --> 00:13:57,300
+stroma بادي إن هو يصير thin في جدّي جنسي التأكل
+
+159
+00:13:57,300 --> 00:14:04,400
+يعني ونلاقي كم كبير من الخلايا البارعة البيضاء في
+
+160
+00:14:04,400 --> 00:14:15,610
+قاع القلصة طيب نمر تلاتة الفاحص مشخصهيلهلاحظ إن
+
+161
+00:14:15,610 --> 00:14:21,190
+الـ stroma بعد أكثر فيها نكروزيز ذوبان في الـ stroma
+
+162
+00:14:21,190 --> 00:14:26,900
+وهذا خطير لأن لو رحت الـ stroma هتصير perforation شوفنا
+
+163
+00:14:26,900 --> 00:14:30,260
+حالات صار لها perforation شوفنا حالات صار لها
+
+164
+00:14:30,260 --> 00:14:34,700
+perforation يبقى الـ stroma اللي احنا بسيطنا بشوفها
+
+165
+00:14:34,700 --> 00:14:40,780
+حوالي 500 مليمتر فاللي جايها 100 أو 200 تقريبا
+
+166
+00:14:40,780 --> 00:14:47,780
+بيقول إن الكولاجين bundles بتاعة الـ stroma اه بدأت إن
+
+167
+00:14:47,780 --> 00:14:50,640
+هي تتحلل
+
+168
+00:14:52,200 --> 00:14:58,940
+في نفس الوقت الـ Descemet membrane وهو الطبقة الرابعة
+
+169
+00:14:58,940 --> 00:15:03,660
+في القرنية يعني أول طبقة Epithelium ثاني طبقة 
+
+170
+00:15:03,660 --> 00:15:08,540
+Bowman's membrane ثالث طبقة Stroma رابع طبقة Descemet
+
+171
+00:15:08,540 --> 00:15:12,740
+membrane آخر طبقة داخلها اسمها Endothelium الحقيقة
+
+172
+00:15:12,740 --> 00:15:17,420
+أنه ثبت إن الـ Descemet membrane من أقوى الطبقات في 
+
+173
+00:15:17,420 --> 00:15:21,080
+القرنية إنه يعني بيقاوم الـ infection ومرور
+
+174
+00:15:21,080 --> 00:15:24,940
+البكتيريا يعني هو هيكون هنا تقريبا و الـ stroma
+
+175
+00:15:24,940 --> 00:15:31,860
+Descemet membrane ومنه جوا طبقة الـ endothelium فهو هذا
+
+176
+00:15:31,860 --> 00:15:37,300
+بيقاوم الـ Descemet membrane يعني بقدر الإمكان بيقاوم الـ
+
+177
+00:15:37,300 --> 00:15:42,210
+enzymatic البكتيريا وبتدوب بش يعني فاحنا ممكن إن
+
+178
+00:15:42,210 --> 00:15:46,970
+نلاقي إنه resistant ومازال Impact Impact يعني
+
+179
+00:15:46,970 --> 00:15:54,890
+سليم ووقف بس هذا طبعا هو رجّيخ جدا يعني طيب هلاحظ
+
+180
+00:15:54,890 --> 00:15:59,920
+أنه لو طلعنا بِسُتِخلام في الـ anterior chamber هنلاقي
+
+181
+00:15:59,920 --> 00:16:04,060
+فيها reaction خلايا التهابية يعني خلايا التهابية
+
+182
+00:16:04,060 --> 00:16:08,280
+وبالتالي reaction هذا عمل Trabeculitis أي
+
+183
+00:16:08,280 --> 00:16:11,340
+Trabecula مشورّك اللي في الـ angle of anterior
+
+184
+00:16:11,340 --> 00:16:15,980
+chamber هنلاقي اللي فيه Trabeculitis التهاب في
+
+185
+00:16:15,980 --> 00:16:22,500
+Trabecula مشورّك ولاحظ فيه Iritis اللي هو القزحية
+
+186
+00:16:22,500 --> 00:16:26,990
+الملتهبة وممكن تجد على الـ lens capsule فيه
+
+187
+00:16:26,990 --> 00:16:30,670
+deposits من خلايا المناعية هذه deposits على الـ
+
+188
+00:16:30,670 --> 00:16:35,550
+lens capsule الأمامية للعدسة البلورية طبعا ممكن إن
+
+189
+00:16:35,550 --> 00:16:41,310
+ما تكونش كل العلامات هذه الخمسة موجودة مع بعض يعني
+
+190
+00:16:41,310 --> 00:16:44,530
+كون إن أنا حاطط الـ fluorescein ولجيت الـ
+
+191
+00:16:44,530 --> 00:16:51,430
+epithelium في defect مسبوق يعني بأزرق مثلا بقول اه
+
+192
+00:16:51,430 --> 00:16:59,990
+هذه البداية هنا فيه اللي هو الـ Elsas يعني ممكن جدا هاي
+
+193
+00:16:59,990 --> 00:17:07,570
+شايفين يعني هاي اللي هو أنا صبّغت fluorescein و
+
+194
+00:17:07,570 --> 00:17:14,850
+بعدين أعطاني لون بني أو ذهبي اه بقول هذا كون الـ
+
+195
+00:17:14,850 --> 00:17:20,310
+Elsas يعني إنه أول شيء إن الـ epithelium في detect
+
+196
+00:17:21,150 --> 00:17:24,570
+يعني لو أنا حطيت في الـ fluorescein علاقة intact
+
+197
+00:17:24,570 --> 00:17:29,090
+epithelium لأ بيعطيش اللون هذا الذهبي أو الأصفر
+
+198
+00:17:29,090 --> 00:17:34,230
+اللي بيعطي إنه يكون في defect of epithelium زي
+
+199
+00:17:34,230 --> 00:17:39,110
+احنا ما قلنا في defect of بيكون absent فهذه
+
+200
+00:17:39,110 --> 00:17:43,270
+العلامة الأولى لكن العلامات التانية بتيجي بتأخر
+
+201
+00:17:43,270 --> 00:17:45,770
+مثلا الـ stroma النكروز اللي ما يصيرش في أول يوم و ثاني
+
+202
+00:17:45,770 --> 00:17:49,430
+يوم و تلاتي يوم النكروز هذا يعني أقل شيء هيكون بعد
+
+203
+00:17:49,430 --> 00:17:53,820
+أربع أيام اللي هو من غير علاج حتى Stromal Necrosis
+
+204
+00:17:53,820 --> 00:17:58,660
+و كتير مثلا يصير Trabeculitis و Iritis و Diphtheria
+
+205
+00:17:58,660 --> 00:18:03,000
+يعني بالقليل بعد أسبوع أو عشر أيام أو عشر أيام
+
+206
+00:18:03,000 --> 00:18:05,560
+يبقى اللي بيشخص بيشخص في الأول على القرنية
+
+207
+00:18:05,560 --> 00:18:08,480
+الـ epithelium وما تطلع يبقى فلوريسين وشوف اللون
+
+208
+00:18:08,480 --> 00:18:15,420
+الذهبي أو اللون الأصفر five هذه صورة تمثيلية كيف
+
+209
+00:18:15,420 --> 00:18:20,500
+القرنية الـ ulcer وكيف الـ epithelium مراحلها يعني كل
+
+210
+00:18:20,500 --> 00:18:25,100
+الـ inflammation هذا اللي براني هذا في المنطقة المركزية
+
+211
+00:18:25,100 --> 00:18:30,760
+من هنا إلى هنا راح وكيف حتى الـ stroma راحت
+
+212
+00:18:30,760 --> 00:18:35,720
+ومافضلش إلا شوية الـ Descemet membrane الأخير هذا هو والـ
+
+213
+00:18:35,720 --> 00:18:40,960
+endothelium يعني هذه الصورة صورة يعني تحاتي يعني
+
+214
+00:18:40,960 --> 00:18:47,680
+ما يحدث في عين المصاب ببكتيريا الـ keratitis هذه هنا
+
+215
+00:18:48,240 --> 00:18:54,700
+لما يتأخر صار الـ stroma نفسه والـ collagen يتآكل يتآكل
+
+216
+00:18:54,700 --> 00:19:00,780
+بالتدريج وبالتالي في الـ stroma الكولاجين destruction
+
+217
+00:19:00,780 --> 00:19:08,820
+destruction يعني ذمار أو خراب طيب الكاتب بيقول هنا
+
+218
+00:19:08,820 --> 00:19:15,330
+أنه يعتقد أنه لما احنا شخصنا وبنعالجها بدي أنا
+
+219
+00:19:15,330 --> 00:19:20,270
+أعالج بِـ shotgun shotgun يعني إطلاق النار على اللي
+
+220
+00:19:20,270 --> 00:19:24,830
+يقول بكتيريا shotgun يعني إطلاق النار مش مهادنة عن
+
+221
+00:19:24,830 --> 00:19:28,270
+طريق بس الـ antibiotic therapy علاجه بالـ antibiotic
+
+222
+00:19:28,270 --> 00:19:31,330
+إيش
+
+223
+00:19:31,330 --> 00:19:34,830
+الـ antibiotic اللي موجود في السوق احنا لازم نكون
+
+224
+00:19:34,830 --> 00:19:40,010
+عارفينه إيش القوي وإيش الضعيف بيقول لي إن أنا يعني
+
+225
+00:19:40,010 --> 00:19:45,800
+مازلت إن أنا يعني بعالج كل البكتيريا الـ ulcer
+
+226
+00:19:45,800 --> 00:19:52,400
+بسبوخها بالـ gram stain في الأول عشان أعرف هي gram
+
+227
+00:19:52,400 --> 00:19:56,240
+negative ولا gram positive يعني هي بتاخد اللون
+
+228
+00:19:56,240 --> 00:19:59,900
+الأزرق ولا اللون الأحمر زي ما قلنا في الـ stains في
+
+229
+00:19:59,900 --> 00:20:07,060
+الأول عشان الـ gram stain positive له علاج و
+
+230
+00:20:07,060 --> 00:20:10,940
+negative له علاج يعني احنا زي ما قلنا إن gram هذا
+
+231
+00:20:10,940 --> 00:20:14,710
+العالم الإنجليزي يعني خدم البشرية فيه يعني حتى مش
+
+232
+00:20:14,710 --> 00:20:20,550
+في العين بس في باقي الجسم كان الصبغة بينت اللون
+
+233
+00:20:20,550 --> 00:20:24,470
+الأزرق يعني العلاجات بتختلف والأمراض بتختلف إن
+
+234
+00:20:24,470 --> 00:20:29,030
+بينت أحمر gram negative gram negative يعني تختلف من
+
+235
+00:20:29,030 --> 00:20:34,190
+واحدة لواحدة فبيقول لي أنا عشان بعمل gram عشان أميز
+
+236
+00:20:34,190 --> 00:20:39,630
+الـ gram positive من negative وعشان أطلع الـ fungal
+
+237
+00:20:39,630 --> 00:20:44,260
+infections لازم نكون أكان ثموبة اللي اتكلمنا عنها
+
+238
+00:20:44,260 --> 00:20:48,020
+قبل شوية هذه لا بتاخد أحمر ولا بتاخد أزرق الـ
+
+239
+00:20:48,020 --> 00:20:51,820
+fungus هذا له صفقة لحاله الـ fungal infections له
+
+240
+00:20:51,820 --> 00:20:58,600
+صفقة لحالها طيب بيقول لي أنا يعني من يوم ما طلعت
+
+241
+00:20:58,600 --> 00:21:04,480
+قطرات جديدة fluoroquinolones مجموعة الأفلوكس و
+
+242
+00:21:04,480 --> 00:21:16,210
+أعلى شوية و فلوكسين وفلوكسين وفلوكسين 
+
+243
+00:21:16,210 --> 00:21:16,890
+وفلوكسين وفلوكسين وفلوكسين وفلوكسين وفلوكسين
+
+244
+00:21:16,890 --> 00:21:19,410
+وفلوكسين وفلوكسين وفلوكسين وفلوكسين وفلوكسين
+
+245
+00:21:19,410 --> 00:21:22,070
+وفلوكسين وفلوكسين وفلوكسين وفلوكسين وفلوكسين
+
+246
+00:21:22,070 --> 00:21:24,450
+وفلوكسين وفلوكسين وفلوكسين وفلوكسين وفلوكسين
+
+247
+00:21:24,450 --> 00:21:29,350
+وفلوكسين وفلوكسين
+
+248
+00:21:29,350 --> 00:21:36,530
+وفلوكسين وفلوكسين مش جبارة يعني بتغطيش gram
+
+249
+00:21:36,530 --> 00:21:40,130
+positive و gram negative spectrum بتاعها narrow بس
+
+250
+00:21:40,130 --> 00:21:45,750
+هذه fluoroquinolones لها wide wide spectrum ضد
+
+251
+00:21:45,750 --> 00:21:50,170
+gram negative وضد gram positive بفكرها ولهذا
+
+252
+00:21:50,170 --> 00:21:55,810
+اللي سهل العلاج لكون الـ ulcer اللي سهل الـ
+
+253
+00:21:55,810 --> 00:22:02,090
+reevaluation اللي قعدت تقييم خطورة وسهل الـ
+
+254
+00:22:02,090 --> 00:22:08,680
+diagnosis اه تسهر الـ treatment ظهور مجموعات 
+
+255
+00:22:08,680 --> 00:22:15,680
+antibiotic متقدمة تستطيع إن تكون عملاقة في علاج الـ
+
+256
+00:22:15,680 --> 00:22:24,060
+corneal ulcers  شيرته كمان إنه بطلنا احنا نعمل
+
+257
+00:22:24,060 --> 00:22:28,580
+routine laboratory evaluation يعني نودع المعمل 
+
+258
+00:22:28,580 --> 00:22:35,350
+عيناك كلّ  الـ ulcer يعني زمان كان لازم ياخد مسحة و
+
+259
+00:22:35,350 --> 00:22:40,650
+يحطها في أنبوبة معقمة و يوديها و يعملولها أول شيء
+
+260
+00:22:40,650 --> 00:22:45,330
+stain و culture وانت بقى كده sensitivity test
+
+261
+00:22:45,330 --> 00:22:49,390
+بيقول لك لأ بطلنا نعمل routine laboratory evaluation
+
+262
+00:22:49,390 --> 00:22:58,820
+لكلّ الـ ulcer ليش؟ لأنه 96% من الـ ulcer هي بس 4% لما
+
+263
+00:22:58,820 --> 00:23:05,700
+بتطولها العلاج العلاج التجريبي والقطرات المقوّاة 
+
+264
+00:23:05,700 --> 00:23:13,760
+اللي دخلت بقوة في العلاج خلت 96% من البكتيريا ومن
+
+265
+00:23:13,760 --> 00:23:18,100
+الـ ulcer اللي هي بتعملها تحت الـ control تحت
+
+266
+00:23:18,100 --> 00:23:25,110
+التحكم بتاع الأطباء طيب احنا هنا يعني مثل كيف هيكون
+
+267
+00:23:25,110 --> 00:23:29,750
+الـ ulcer في البداية بدأ الـ leukocytic الـ
+
+268
+00:23:29,750 --> 00:23:33,030
+infiltration الـ leukocytic اللي هو خلايا الدم البيضاء
+
+269
+00:23:33,030 --> 00:23:42,330
+طيب هاي واحد طب اتنين اه صار نوع من اللي هو
+
+270
+00:23:42,330 --> 00:23:46,090
+خلايا الدم البيضاء تعمل اللي هو نوع من السيطرة 
+
+271
+00:23:46,090 --> 00:23:51,010
+على البكتيريا تعمل Regression يعني بعض التحسن بس
+
+272
+00:23:51,010 --> 00:23:55,550
+بدون علاج يعني احنا إذا دخلوا طباء هتصير
+
+273
+00:23:55,550 --> 00:24:02,510
+scarring تليف في الإصابة والتليف يعني معناه 
+
+274
+00:24:02,510 --> 00:24:07,350
+أنه أصبحت القرنية معتمة اه لما يقول scar أو
+
+275
+00:24:07,350 --> 00:24:11,030
+scarring يعني صارت القرنية معتمة وهذا ما فيش
+
+276
+00:24:11,030 --> 00:24:15,420
+علاج فعلا أصبحت معتمة خاصة إن أخذت Bowman's membrane في
+
+277
+00:24:15,420 --> 00:24:19,840
+طريقها بيصير ما فيش شفاء إلا بعد هيك نقل قرنية
+
+278
+00:24:19,840 --> 00:24:27,320
+خاصة لو كانت في المركز بتاع القرنية طيب بيقول لي
+
+279
+00:24:27,320 --> 00:24:30,840
+الـ ophthalmologist اه في البداية اللي هو طبيب 
+
+280
+00:24:30,840 --> 00:24:36,020
+العيون هيعمل تشخيص لـ immediate diagnosis يعني
+
+281
+00:24:36,020 --> 00:24:42,750
+تركيز للأثر في المكتب أو في العيادة ويعطي الـ
+
+282
+00:24:42,750 --> 00:24:46,090
+Commercial Available Antibiotics يعني القطرات اللي 
+
+283
+00:24:46,090 --> 00:24:53,150
+هي في السوق أو متوفرة ويعني الـ cultures هاري بتاعة 
+
+284
+00:24:53,150 --> 00:24:56,890
+أن ياخد قبل ما يعطي القطرات يعني يعمل cultures
+
+285
+00:24:56,890 --> 00:25:04,630
+اللي هو مزارع بكتيرية يقولنا إيش نوع البكتيريا يعني كتير
+
+286
+00:25:04,630 --> 00:25:09,630
+بيعملوهاش أنا شخصياً نادر ما عملتها إلا إذا كان
+
+287
+00:25:09,630 --> 00:25:13,350
+الأثر worsens و worsens يعني أسوأ يعني أنا بعطيه 
+
+288
+00:25:13,350 --> 00:25:17,390
+علاج وهو بسوء في الآخر أنا مضطر أني أعمل culture
+
+289
+00:25:17,390 --> 00:25:22,250
+لكن يعني طريقتي أني أنا بعطي أكثر موضوع حيوي قوي 
+
+290
+00:25:22,250 --> 00:25:27,910
+وبتابع العيان يومياً حتى أني أشوف نتيجة بده حسن ولو
+
+291
+00:25:27,910 --> 00:25:31,850
+أدى إلى أن ياخذ العلاج لشهور طيب 
+
+292
+00:25:33,410 --> 00:25:35,850
+ماهي risk factors من risk factors اللي احنا 
+
+293
+00:25:35,850 --> 00:25:40,730
+اتكلمنا عنها في كون الأثر حاجة كتيرة لكن هلّأ هو 
+
+294
+00:25:40,730 --> 00:25:46,570
+خلّى حاجتين بس خلّى الـ soft lens wear اللي بيستعمل 
+
+295
+00:25:46,570 --> 00:25:53,090
+اللي هو العدسات اللاصقة إذا تلوتت بالـ pseudomonas
+
+296
+00:25:53,090 --> 00:25:57,450
+الـ pseudomonas أي جنوزة نوع من البكتيريا الشريرة 
+
+297
+00:25:58,030 --> 00:26:02,310
+تستطيع أن تخترق العين السليمة يعني العين السليمة
+
+298
+00:26:02,310 --> 00:26:06,490
+اللي مش فيها خدش ولا ضربة ولا عملية غيرها هي ممكن
+
+299
+00:26:06,490 --> 00:26:11,290
+السودوموناس لو دخلت فيها وعششت وكترت في كيس
+
+300
+00:26:11,290 --> 00:26:15,210
+المتحمة والجفون ممكن تخترق الـ intact eye أو الـ
+
+301
+00:26:15,210 --> 00:26:20,690
+healthy eye يبقى إيش كيف الآن السودوموناس وصلت لـ
+
+302
+00:26:20,690 --> 00:26:25,910
+soft contact lens اللي بيعملها بالبس المريض غالباً 
+
+303
+00:26:25,910 --> 00:26:31,450
+أنه يكون المحلول مغشوش أو المحلول ملوث أو ميت
+
+304
+00:26:31,450 --> 00:26:35,970
+حنفية فيها سودوموناس ملوثة بالسودوموناس وهذا شيء
+
+305
+00:26:35,970 --> 00:26:39,390
+خطير جداً ونصيحة للناس اللي بدهم يستعملوا الـ
+
+306
+00:26:39,390 --> 00:26:44,050
+contact lenses أنه يحرصوا على النظافة والتطهير و
+
+307
+00:26:44,050 --> 00:26:49,890
+التعقيم صحيح وإلّا ما يبسّوهاش الثاني أن يكون فيه 
+
+308
+00:26:49,890 --> 00:26:58,010
+مُصاحب للأثر blepharitis التهاب حواف الجفون اللي جاية
+
+309
+00:26:58,010 --> 00:27:01,710
+من staphylococcus aureus وكتير staphylococcus 
+
+310
+00:27:01,710 --> 00:27:06,630
+aureus هذه لبدنة مع إصلاح الشعر أو مع بصيلات الشعر 
+
+311
+00:27:06,630 --> 00:27:13,970
+وهذه دائماً قريبة تستنى أي انتهازية تستنى أي فتحة
+
+312
+00:27:13,970 --> 00:27:17,230
+فيه الـ epithelium وتدخل شلون يبقى دولة عوامل خطر
+
+313
+00:27:17,230 --> 00:27:26,700
+كبرى خلينا نسميها طيب ما هي العوامل التي توجد دخول
+
+314
+00:27:26,700 --> 00:27:31,060
+لابد أن ندخل المريض إلى المستشفى يعني أنا غالباً
+
+315
+00:27:31,060 --> 00:27:34,720
+لما يجيني واحد معاه الأثر باعطيه العلاج وبفهمه
+
+316
+00:27:34,720 --> 00:27:40,400
+كيف يعمل وبقوله كل يوم يجيني عشان أنا أتابعه أو 
+
+317
+00:27:40,400 --> 00:27:45,280
+كله من يجيني حسب لكن في ناس لازم أبعتهم مع 
+
+318
+00:27:45,280 --> 00:27:49,760
+المستشفى ما نفعش أن أنا أكتب له القاعدة وأقول له روح
+
+319
+00:27:50,560 --> 00:27:55,160
+بقول لك إيش عوامل أو وجوب دخول المستشفى أول شيء 
+
+320
+00:27:55,160 --> 00:28:00,540
+عدم قدرة المريض أو العائلة بتاعته على أن تكون 
+
+321
+00:28:00,540 --> 00:28:05,300
+منصاعة للعلاج يعني أنا مع الأولاد بقول القطرة كل 
+
+322
+00:28:05,300 --> 00:28:10,380
+ساعة طب هو إيش عن ولد صغير هو أمه مش قادرة أو مش 
+
+323
+00:28:10,380 --> 00:28:16,820
+فاهمة يبقى إذا كان أمه مش فاهمة أو طفل صغير جاهل 
+
+324
+00:28:16,820 --> 00:28:20,720
+قاصر بده مستشفى hospitalization كلمة
+
+325
+00:28:20,720 --> 00:28:23,440
+hospitalization يعني admission للمستشفى admission
+
+326
+00:28:23,440 --> 00:28:29,420
+الشيء الثاني بيخلّيني أنا أدخله للمستشفى أن كان
+
+327
+00:28:29,420 --> 00:28:37,800
+ب يكفيش فقط اللي هو الدمعة وبده حُقن تحت الملتحمة
+
+328
+00:28:37,800 --> 00:28:39,260
+subconjunctival injection
+
+329
+00:28:48,950 --> 00:28:53,090
+الثالثة أنه أنا باعطيه إلهي لكن شايف الوضع بسوء و
+
+330
+00:28:53,090 --> 00:28:57,990
+القرنية خاصة trauma rapid thinning يعني عملت أكل
+
+331
+00:28:58,550 --> 00:29:02,430
+القرنية بدأت تدوب فبخاف من الـ perforation اختراق 
+
+332
+00:29:02,430 --> 00:29:07,150
+القرنية فأنا بُودي على المستشفى بُودي على المستشفى
+
+333
+00:29:07,150 --> 00:29:11,890
+بريح إذا لو قلنا ما هي العوامل التي توجد دخول
+
+334
+00:29:11,890 --> 00:29:17,050
+المستشفى واحد اثنين ثلاث أرجو أن تحطوها في مخه
+
+335
+00:29:17,050 --> 00:29:26,390
+كويس طبعاً بقول الآن بالنسبة لـ Chlorokolanon therapy
+
+336
+00:29:26,390 --> 00:29:32,450
+أن هذه typical دكتور بكالي يعني Drug fluoro quinolone
+
+337
+00:29:32,450 --> 00:29:38,650
+Therapy أنا هذه عالمية حقيقة الـ بيجاموكس
+
+338
+00:29:38,650 --> 00:29:45,010
+والزايمكسيد والزايمر والفحمة هذه الغالية بس في بعض
+
+339
+00:29:45,010 --> 00:29:51,150
+البكتيريا قد لا تستجيب لها خاصة في الناس اللي 
+
+340
+00:29:51,150 --> 00:29:55,970
+بيلبسوا الـ contact lens smooth أكثر extended wear 
+
+341
+00:29:55,970 --> 00:30:00,490
+أو soft contact lens يعني واحد يقول لك أنا يا عم هذه 
+
+342
+00:30:00,490 --> 00:30:04,210
+contact lens this is visible بس أنا بلبسها أسبوعين
+
+343
+00:30:04,210 --> 00:30:10,410
+أو ثلاث أسابيع وبأشيلهاش هذا وهي ملوثة بالبكتيريا
+
+344
+00:30:10,410 --> 00:30:15,170
+ممكن الـ topical chlorokolanon القطرات هذه ما تجيبش 
+
+345
+00:30:15,170 --> 00:30:18,670
+لأن ممكن تكون فيها pseudomonas و pseudomonas ممكن 
+
+346
+00:30:18,670 --> 00:30:22,930
+ما تجيبش كتير أو أن أنا شكيت السودوموناس أن الـ gram 
+
+347
+00:30:22,930 --> 00:30:26,250
+negative في البكتيريا ممكن ما تغطيهاش قطرات
+
+348
+00:30:26,250 --> 00:30:30,310
+كلوروكولانون زي الناس وبده علاج مختلف مع أن هذه
+
+349
+00:30:30,310 --> 00:30:36,620
+جبارة كتير لكن السودوموناس تتمرد عليها طيب يبقى 
+
+350
+00:30:36,620 --> 00:30:40,380
+هدول الـ pseudomonas بدهم anti-pseudomonal
+
+351
+00:30:40,380 --> 00:30:47,400
+treatment يعني يبقى علاج خاص فيهم مش زي الباقين آه 
+
+352
+00:30:47,400 --> 00:30:53,280
+يبقى لو أنا شكيت أنه من البداية أنه في pseudomonas
+
+353
+00:30:53,280 --> 00:30:59,170
+الجنوزة بكتيريا قرنية العملة اللي هو الـ ciprofloxacin
+
+354
+00:30:59,170 --> 00:31:05,270
+هذه بدي أعطي أنا Anti-pseudomonal therapy تيرابي 
+
+355
+00:31:05,270 --> 00:31:14,050
+يعني علاج Anti يعني مضاد إلها آه ويعني التأخير
+
+356
+00:31:14,050 --> 00:31:20,130
+مش في صالح المريض لأنه حيثما للـ trauma تفتت وده 
+
+357
+00:31:20,130 --> 00:31:22,410
+وبن طيب 
+
+358
+00:31:24,750 --> 00:31:29,330
+الآن الحقيقة يعني العلاج الأساسي هو القطرة طبيعي 
+
+359
+00:31:29,330 --> 00:31:33,690
+لكن في ناس بيقول لك يا عمي أنا بدأت أنقذ القرنية لأن 
+
+360
+00:31:33,690 --> 00:31:38,810
+القرنية هي لغاية يعني راحت القرنية وصارت معتمقة 
+
+361
+00:31:38,810 --> 00:31:43,270
+opaque يعني لغاية بتروح فصار الآن يعني الأطباء
+
+362
+00:31:43,270 --> 00:31:49,370
+بيجمعوا ما بين drops antibiotic eye drops وبين an
+
+363
+00:31:49,370 --> 00:31:53,710
+subconjunctival injection injection يعني حقن يعني 
+
+364
+00:31:53,710 --> 00:31:59,390
+لما تكون البكتيريا تتعرض لقطرات تتعرض لحقن خاصة
+
+365
+00:31:59,390 --> 00:32:04,590
+يومية تحت الملتحمة بيكون فيه مصدرين للـ antibiotic
+
+366
+00:32:04,590 --> 00:32:11,010
+وبالتالي بيكون أكثر تأثيراً وقتلاً للبكتيريا ومحاولة
+
+367
+00:32:11,010 --> 00:32:17,250
+نجاح للقرنية من الضياء ومن الدوبان طيب الـ
+
+368
+00:32:17,250 --> 00:32:24,810
+injection هذا تحت القرنية بيكثر في حالة عدم 
+
+369
+00:32:24,810 --> 00:32:30,490
+الالتزام والطاعة للعلاج خاصة في الرضع والأطفال 
+
+370
+00:32:30,490 --> 00:32:35,430
+الصغار الـ young children الصغار والرضع حقيقة بدهم
+
+371
+00:32:35,430 --> 00:32:40,150
+اللي هو الحقنة ب يكشف همش القطرات أو بيتمردوا حتى
+
+372
+00:32:40,150 --> 00:32:44,670
+على القطرات طيب لو نشوف إحنا يعني إيش هو العلاج
+
+373
+00:32:44,670 --> 00:32:49,090
+الدالي للسودومونال السودومونال السودومونال
+
+374
+00:32:49,090 --> 00:32:50,830
+السودومونال السودومونال السودومونال السودو
+
+375
+00:32:50,830 --> 00:32:55,790
+مونال السودومونال السودومونال السودومونال
+
+376
+00:32:55,790 --> 00:32:59,210
+السودومونال السودومونال السودومونال السودو
+
+377
+00:32:59,210 --> 00:32:59,870
+مونال السودومونال السودومونال السودومونال
+
+378
+00:32:59,870 --> 00:32:59,950
+السودومونال السودومونال السودومونال السودو
+
+379
+00:32:59,950 --> 00:33:00,230
+مونال السودومونال السودومونال السودومونال
+
+380
+00:33:00,230 --> 00:33:02,730
+السودومونال السودومونال السودومونال السودو
+
+381
+00:33:02,730 --> 00:33:05,510
+مونال السودومونال السودومونال السودومونال
+
+382
+00:33:05,510 --> 00:33:12,610
+السودو
+
+383
+00:33:12,610 --> 00:33:17,110
+موناس طبراحة ماشين هو نفسه باعطيه تحت الملتحمة يعني 
+
+384
+00:33:17,110 --> 00:33:22,330
+المصدرين عشان أنقذ العين من البكتيريا المدمرة
+
+385
+00:33:22,330 --> 00:33:27,070
+سودوموناس إيريجينوزا دي طيب لو كان استخدم كوكياس آه 
+
+386
+00:33:27,070 --> 00:33:31,050
+استخدم كوكياس آه ما رها أحسن يعني أنا من أساس ممكن
+
+387
+00:33:31,050 --> 00:33:36,070
+أعطيها اللي هو fluoroquinolone لكن في ناس كانوا 
+
+388
+00:33:36,070 --> 00:33:40,430
+جابلك هيك جاب لك fluoroquinolone يعطيها بس تريسين 
+
+389
+00:33:41,510 --> 00:33:47,030
+بسترسين في قطرة ويعطيها حقن بانثمايسين جي تحت 
+
+390
+00:33:47,030 --> 00:33:50,690
+القرنية وإذا كان فيه حسية عنده يغيروا البانثمايسين
+
+391
+00:33:50,690 --> 00:33:55,670
+إلى دين تابايسيل لكن أنا في ظني أن ستافيلوكوكاس الأثر 
+
+392
+00:33:55,670 --> 00:34:00,410
+ممكن لو أعطيته أنا فلوروكوينولون زي زايمكسيد أو 
+
+393
+00:34:00,410 --> 00:34:04,370
+زايمر أو فيجاموكس أعطيته كل ساعتين كل ساعتين كل 
+
+394
+00:34:04,370 --> 00:34:07,390
+ساعتين كل ساعتين اثنا عشر مرة في اليوم في خلال أسبوع
+
+395
+00:34:07,390 --> 00:34:12,270
+بيبدا يكشف إن شاء الله وممكن أريحه أنا من خوخة لكن 
+
+396
+00:34:12,270 --> 00:34:17,820
+هذا الـ regime القديم أنه أحسن بيقول لك تعطي قطرة زائد 
+
+397
+00:34:17,820 --> 00:34:25,280
+حقن طيب لو هو عنده حسية بانسلين هغير بانسلين أنا 
+
+398
+00:34:25,280 --> 00:34:30,620
+بشيء ثاني مثلاً أعطي بسترسين أو بنكميسين مضاد حيوي 
+
+399
+00:34:30,620 --> 00:34:38,060
+قطرة وبعدها أعطي صفة زولين أو حقن صفة زولين في
+
+400
+00:34:38,060 --> 00:34:46,520
+اسمها مثلاً في جرام نيجاتيف الأثر جرام نيجاتيف زي 
+
+401
+00:34:46,520 --> 00:34:51,100
+بروتيس وزاي كلب سلة وزي اشريشيا كولاي وزي 
+
+402
+00:34:51,100 --> 00:34:55,920
+إنتروبكتر هذول قليل صحيح أن حدوثهم في القرنية
+
+403
+00:34:55,920 --> 00:35:00,980
+أنهم يعملوا أثر لأن دخولهم للعين أقل من أول برضه
+
+404
+00:35:00,980 --> 00:35:04,680
+هذول بدهم حقن وبدهم حقن وبدهم حقن
+
+405
+00:35:10,860 --> 00:35:17,080
+توبراميسين قطرة نفس الشيء توبراميسين أو تيتراميسين أو 
+
+406
+00:35:17,080 --> 00:35:17,920
+تيتراميسين أو تيتراميسين أو تيتراميسين أو تيتراميسين
+
+407
+00:35:17,920 --> 00:35:18,520
+أو تيتراميسين أو تيتراميسين أو تيتراميسين أو
+
+408
+00:35:18,520 --> 00:35:20,400
+تيتراميسين أو تيتراميسين أو تيتراميسين أو تيتراميسين
+
+409
+00:35:20,400 --> 00:35:23,080
+أو تيتراميسين أو تيتراميسين أو تيتراميسين أو
+
+410
+00:35:23,080 --> 00:35:27,260
+تيتراميسين أو تيتراميسين طيب يعني أنا ممكن أن أقول 
+
+411
+00:35:27,260 --> 00:35:34,180
+أنه إحنا بلغنا مبلغ جيد حقيقة ويعني هنتوقف عند اللي
+
+412
+00:35:34,180 --> 00:35:37,540
+هو الـ endophthalmitis اللي هو intraocular
+
+413
+00:35:37,540 --> 00:35:42,260
+bacterial infections يعني لو البكتيريا اخترقت قرنية 
+
+414
+00:35:42,260 --> 00:35:46,220
+ودخلت جوا العين هتعمل endophthalmitis هاري هيكون 
+
+415
+00:35:46,220 --> 00:35:50,440
+موضوع المحاضرة القادمة إن شاء الله عشان إحنا نمشي 
+
+416
+00:35:50,440 --> 00:35:56,300
+systematic وإنتوا يعني تستفيدوا من اللي هو 
+
+417
+00:35:56,300 --> 00:36:02,020
+المحاضرات لما تكون المحاضرات هذه في هذا الشكل وفي 
+
+418
+00:36:02,020 --> 00:36:04,380
+هذا الشكل شكراً لكم والسلام عليكم
diff --git a/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/QMK5WJmZzkk_postprocess.srt b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/QMK5WJmZzkk_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..5f25d1571ba9dae51d858b4c2e94f6d74e395103
--- /dev/null
+++ b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/QMK5WJmZzkk_postprocess.srt
@@ -0,0 +1,1072 @@
+1
+00:00:12,040 --> 00:00:17,100
+عودوا لكم في
+
+2
+00:00:17,100 --> 00:00:21,980
+المحاضرة الحادية والثلاثين حول الفيروسات التي تصيب
+
+3
+00:00:21,980 --> 00:00:28,400
+العينواخدنا ثلاثة من هذه العائلة ال herpes viruses
+
+4
+00:00:28,400 --> 00:00:31,800
+واليوم هناخد الرابع والخامس ان شاء الله العدو
+
+5
+00:00:31,800 --> 00:00:35,980
+الرابع والخامس العدو
+
+6
+00:00:35,980 --> 00:00:43,380
+الرابع هو ال versilia zoster اللي بيقول عنه herpes
+
+7
+00:00:43,380 --> 00:00:52,280
+zoster virus HZV herpes zoster virusهذا يعني
+
+8
+00:00:52,280 --> 00:00:56,840
+بالعربي بيسموه فيروس الحزام الناري الحزام الناري
+
+9
+00:00:56,840 --> 00:01:01,160
+ليش؟ لأنه اصيب نصف الجسم اما اليمين واما الشمال
+
+10
+00:01:01,160 --> 00:01:08,060
+خاصة في الرأس وفي الوجه وفي الرقبة هو بيقول انه
+
+11
+00:01:08,060 --> 00:01:13,480
+عضو من ال headless viruses وكلهم double strand DNA
+
+12
+00:01:13,480 --> 00:01:17,360
+viruses
+
+13
+00:01:18,750 --> 00:01:25,590
+واضح ان انتشار يوبيكويتوس يجيوله
+
+14
+00:01:25,590 --> 00:01:30,530
+فاكسين سنة 95 قبل ما يجوا الفاكسين كان في ملايين
+
+15
+00:01:30,530 --> 00:01:36,060
+الإصابات في العالم اكتر من 3 مليون مصابفي السنة
+
+16
+00:01:36,060 --> 00:01:41,640
+الواحدة كان في أمريكا بس تحالها تلاتة مليون و لما
+
+17
+00:01:41,640 --> 00:01:47,760
+نجوا ال vaccine يعني خف الموضوع المرض بكتر في فصل
+
+18
+00:01:47,760 --> 00:01:53,620
+الربيع spring طب كيف تتم العدوى العدوى حاجتين اما
+
+19
+00:01:53,620 --> 00:02:00,480
+skin to skin يعني واحد مصاب يلانس واحد سليم skin
+
+20
+00:02:00,480 --> 00:02:09,760
+to skinأو انه الصحيح يصيب الإفرازات التي تخرج من
+
+21
+00:02:09,760 --> 00:02:17,740
+حلق وصدر المريض بقول عن respiratory secretions
+
+22
+00:02:17,740 --> 00:02:23,460
+هو حقيقة ممكن أنه يصيب ال normal الناس الأصحى
+
+23
+00:02:23,460 --> 00:02:27,860
+ويصيب ال immunocompromised وضعيفي المناعم كفر السن
+
+24
+00:02:27,860 --> 00:02:34,510
+ومرضى الأمراض المزمنةطيب بقول في حاجة اسمها
+
+25
+00:02:34,510 --> 00:02:39,150
+genetic predisposition يعني مابصيبش كل الناس بنفس
+
+26
+00:02:39,150 --> 00:02:43,310
+اللي هو القدر لأ بصيب ناس اكتر من ناس و ده يعتمد
+
+27
+00:02:43,310 --> 00:02:48,130
+على استعداد ديني لدى بعض الناس اكتر من ناس اخرين
+
+28
+00:02:49,120 --> 00:02:51,920
+طيب نشوف الـ clinical presentation يعني ايش الصورة
+
+29
+00:02:51,920 --> 00:02:58,120
+الكليكية ما هي العلامات والأعراض التي تصيب الإنسان
+
+30
+00:02:58,120 --> 00:03:04,340
+الإنسان اللي بدأ ينصاب يشعر في وشهه و في رجبته في
+
+31
+00:03:04,340 --> 00:03:07,940
+مكان ما بدأ تصير إصابة ب severe burning burning
+
+32
+00:03:07,940 --> 00:03:13,640
+انشعة يعني بتشعته بحق فيها كتير وبتشعته بعد يومين
+
+33
+00:03:13,640 --> 00:03:19,500
+تلاتة بتطلع blistersيعني أكياس صغيرة تجبه مؤلمة
+
+34
+00:03:19,500 --> 00:03:25,180
+يعني زي رأس الإبرة بربيط صغير جد رأس الإبرة اسمها
+
+35
+00:03:25,180 --> 00:03:30,400
+blisters اسمها blisters وهذه ال blisters بتكون في
+
+36
+00:03:30,400 --> 00:03:35,420
+certain area يعني نقول مثلا نص وجه اليمين و نص رأس
+
+37
+00:03:35,420 --> 00:03:40,500
+اليمين و شوية فرجبة هذه بتتوزع غالبا مع الأفعال
+
+38
+00:03:40,500 --> 00:03:44,310
+مجزمين أو بترايدي من النارالناس تراجع من النار
+
+39
+00:03:44,310 --> 00:03:50,970
+لديها ثلاثة فعوض أفثالمك و مادزيلاري و مانديبلار
+
+40
+00:03:50,970 --> 00:03:59,830
+فهو الأفثالمك الذي يغضي العين و الوجه فهو كثير
+
+41
+00:03:59,830 --> 00:04:04,410
+يغضي العين و الوجه في ناحية من واحد اما اليمين او
+
+42
+00:04:04,410 --> 00:04:08,970
+الشمال و غالبا في اوكولار انفراد هنتكلم عنها اللي
+
+43
+00:04:08,970 --> 00:04:13,890
+بتأثر على ال equity او الانفراد يعنيالعين يجتملها
+
+44
+00:04:13,890 --> 00:04:18,990
+او اشملها هذا الإصارة بعد ال blisters اللى زى رأس
+
+45
+00:04:18,990 --> 00:04:24,030
+الدبوس تبدأ تكبر و تصير مكيولز مكيولز هو بيباب
+
+46
+00:04:24,030 --> 00:04:29,930
+صغيرة اكبر شوية مكيولز المكيولز لما تكبر تصير بحجم
+
+47
+00:04:29,930 --> 00:04:35,390
+العدسة عديسات تابيولز لما تصير بحجم الفولة تصير
+
+48
+00:04:35,390 --> 00:04:40,860
+vesiclesيبقى احنا بدأنا في blisters واحد ايش قولنا
+
+49
+00:04:40,860 --> 00:04:46,720
+blisters البلستر لما تكبر بيصير مكيول بيصير ايش
+
+50
+00:04:46,720 --> 00:04:55,200
+يعني زي عدسة العدسة بتكبر شوية بيصير تبيول يعني
+
+51
+00:04:55,200 --> 00:04:58,780
+اكبر من العدسة ال physical بيصير حبة فولة او اكبر
+
+52
+00:04:58,780 --> 00:05:04,820
+وبعدين بتنبعها لما هي تنفجر ال physical بتعمل
+
+53
+00:05:04,820 --> 00:05:10,240
+crustخشور جشرة يعني زى الجرح بعد كام يوم بتغطى
+
+54
+00:05:10,240 --> 00:05:14,180
+بجشرة المنطقة ال physical هذه بتغطى بجشرة وممكن
+
+55
+00:05:14,180 --> 00:05:19,220
+انا اوريكوا يعنى فالاول كانت acute هيها هذه acute
+
+56
+00:05:19,220 --> 00:05:25,200
+مش فيها جشرة يعنى فالوقت هذا صار chronic
+
+57
+00:05:28,180 --> 00:05:33,000
+هي صاد قشور شايفين قشور كيف بتشوه المنطقة ده
+
+58
+00:05:33,000 --> 00:05:39,060
+شايفين كيف نص الرأس الجبهة و نص الوجه و العين و
+
+59
+00:05:39,060 --> 00:05:44,380
+الخد و الشلم صيبه بينما نص الآخر مش فيه حاجة عشان
+
+60
+00:05:44,380 --> 00:05:50,380
+يسموه الحزام الناري يعني زي غص النار الجهة بتتأثر
+
+61
+00:05:50,380 --> 00:05:53,840
+و الجهة التانية لاتتأثر هي شايفين خط كيف هيو ماشي
+
+62
+00:05:53,840 --> 00:05:59,850
+ماشي الخط هيو حتى نص الانفأدل فبجيش على الناحية
+
+63
+00:05:59,850 --> 00:06:06,870
+هذه كله في الناحية هذه طيب البابليستر مكيوز بكيوز
+
+64
+00:06:06,870 --> 00:06:13,930
+physical خمسة إيش trust بشور بعض الناس اللي
+
+65
+00:06:13,930 --> 00:06:19,390
+الفيروس خش على الرأتين عملهم نيومونيا نيومونيا
+
+66
+00:06:19,390 --> 00:06:22,530
+يعني التهاب رأوي وانت خش على الرأب يعملهم
+
+67
+00:06:22,530 --> 00:06:25,890
+encephalitis يعني التهاب مخي وهذا بتكون في الناس
+
+68
+00:06:25,890 --> 00:06:29,820
+بتاع ال aidsهو الناس بتاني السرطان والعياذ بالله
+
+69
+00:06:29,820 --> 00:06:34,000
+يعني مش كل واحد صاب و الحزم ناري عمله التيابري أوي
+
+70
+00:06:34,000 --> 00:06:37,220
+و انه انت فرقتك ايه ليكون مهزوم مناعيا مهزوم
+
+71
+00:06:37,220 --> 00:06:43,500
+مناعيا طيب ال قولنا انه بيمشي مع الوثان ميكديميجن
+
+72
+00:06:43,500 --> 00:06:48,980
+الفرع الأعلى من العصب اللي تراجمنا العصب المخي
+
+73
+00:06:48,980 --> 00:06:57,410
+الخامس او القحط الخامس ممكن انه بيقولك بصيب25% من
+
+74
+00:06:57,410 --> 00:07:02,850
+المرضى 25% cases of shingles shingles القوبة بقول
+
+75
+00:07:02,850 --> 00:07:09,030
+عنها مجموعة القوب اللي في المرضى 25% منها من ال
+
+76
+00:07:09,030 --> 00:07:14,450
+herpes zoster و 75% من فطريات و أشياء تانية طيب
+
+77
+00:07:14,450 --> 00:07:17,730
+نشوف العين لما نقول of time of cast يعني العين
+
+78
+00:07:17,730 --> 00:07:22,450
+نشوف ال herpes zoster في العين هذا احنا شوفناه في
+
+79
+00:07:22,450 --> 00:07:27,620
+الجلدشوفناها في الرياضي شوفناها في المقهى يبقى هذي
+
+80
+00:07:27,620 --> 00:07:33,680
+ممكن تكون general general clinical presentation
+
+81
+00:07:33,680 --> 00:07:41,840
+هذي general الآن لأ هذي ophthalmicus I يعني في ال
+
+82
+00:07:41,840 --> 00:07:48,920
+I بنقول conductivitis افتهاب الملتحة ابسكليريتس
+
+83
+00:07:48,920 --> 00:07:54,200
+يعني الغطاء بسكليرةscleritis الـ sclera نفسها
+
+84
+00:07:54,200 --> 00:07:58,960
+الصلبة الصلبة ممكن تقضي يعني تدل الجفن العلوي تدل
+
+85
+00:07:58,960 --> 00:08:05,080
+الجفن العلوي طيب الآن دخلنا القرانية هذه برا
+
+86
+00:08:05,080 --> 00:08:10,560
+مستحمة و sclera في sclera طيب القرانية و هي الأخطر
+
+87
+00:08:10,560 --> 00:08:15,240
+ليش أخطر لاتؤثر على النظر punctate منقف يعني
+
+88
+00:08:15,240 --> 00:08:21,140
+immaterial keratitis punctate في ال punctate
+
+89
+00:08:24,490 --> 00:08:31,150
+البنك تيت ال material keratitis عبارة عن multiple
+
+90
+00:08:31,150 --> 00:08:36,590
+legions تتقدم إلى dendritic pattern أو dendritic
+
+91
+00:08:36,590 --> 00:08:41,150
+أثر زي اللي شفناه في ال herpes simplex يعني ممكن
+
+92
+00:08:41,150 --> 00:08:45,210
+جدا انه اللي مش عارف انه هذا herpes zoster انه
+
+93
+00:08:45,210 --> 00:08:48,110
+يقول عنه herpes simplex بس لما يشوف وجهه زي
+
+94
+00:08:48,110 --> 00:08:53,350
+المحروق والجبهة بتاعته اه بقول هذا zoster لكن هي
+
+95
+00:08:54,110 --> 00:08:58,930
+Dendritic يعني دندركتش اللي هو شجرية قرحة شجرية في
+
+96
+00:08:58,930 --> 00:09:03,930
+القرنية طيب الان القرحة الشجرية هذه بتدلش بتخش
+
+97
+00:09:03,930 --> 00:09:10,130
+لورا بتروح ال epithelium اه under ال epithelium من
+
+98
+00:09:10,130 --> 00:09:12,590
+ال epithelium under ال epithelium و بتروح ال
+
+99
+00:09:12,590 --> 00:09:16,370
+stroma تعمل anthelostromal keratitis يبقى دخلة من
+
+100
+00:09:16,370 --> 00:09:20,710
+ال epithelium بومز من brain اللي هو ال antigen
+
+101
+00:09:20,710 --> 00:09:24,950
+antibody يعني نتيجة استفاعل بين الفيروسوكورات الدم
+
+102
+00:09:24,950 --> 00:09:31,150
+المفاوية هو عملت stromal keratitis ايش عملت؟
+
+103
+00:09:31,150 --> 00:09:36,190
+stromal keratitis اه
+
+104
+00:09:36,190 --> 00:09:41,110
+بعد اسبوع من البداية يبقى مش القرانية بيصير فيها
+
+105
+00:09:41,110 --> 00:09:43,310
+stromal keratitis في الأول لأ في الأول بيصير
+
+106
+00:09:43,310 --> 00:09:45,850
+punctate بعدين بيصير
+
+107
+00:09:51,210 --> 00:09:55,650
+اللي هو ايش Stromal او anterior stromal keratitis
+
+108
+00:09:55,650 --> 00:09:58,990
+اللي هو تحت برمز ال brain وشتن بقى حوالي اربعين
+
+109
+00:09:58,990 --> 00:10:07,010
+واسبوع من اصابة بقول انه ال keratitis هالي بتسيب
+
+110
+00:10:07,010 --> 00:10:14,230
+اربعين بالمية من المرضى اللي هو اللي صابهم ال
+
+111
+00:10:14,230 --> 00:10:18,330
+virus اربعين بالمية من اللي اصاب القرانية بتاعتهم
+
+112
+00:10:18,840 --> 00:10:22,720
+بقولنا انه يخلط بينه بين ال herpes similis يخطأ
+
+113
+00:10:22,720 --> 00:10:32,780
+فيه طيب هذه اكيوت اكيوت herpes zoster وهذه chronic
+
+114
+00:10:32,780 --> 00:10:36,560
+يعني هذه لها مسكين شهر و اكتر او شهرين شهرين
+
+115
+00:10:36,560 --> 00:10:42,920
+شايفين كيف الوضع عينه وضع صعب طيب بقولكبعد ما خلص
+
+116
+00:10:42,920 --> 00:10:46,060
+من القرانية و دخل من القرانية راق على ال yuvial
+
+117
+00:10:46,060 --> 00:10:52,220
+tract تعمل yuvietis يعني البهاب الارز والسلري بودي
+
+118
+00:10:52,220 --> 00:10:57,680
+و ممكن يصل للكورويد بس هي ده بقولك يعني بيكون rare
+
+119
+00:10:57,680 --> 00:11:03,360
+خاصة في الناس اللي منعتهم قليلة اه بصيبهم بيكون
+
+120
+00:11:03,360 --> 00:11:10,090
+rare و بيعمل yuvietis ممكن يعمل spleritisممكن يعمل
+
+121
+00:11:10,090 --> 00:11:17,010
+iris atrophy ضمور للقزحية هيبوكيوم يعني عبارة عن
+
+122
+00:11:17,010 --> 00:11:23,630
+صديق في الحجرة الأمامية في العين ممكن يعمل
+
+123
+00:11:23,630 --> 00:11:28,590
+antirosigment necrosis ذوبان في مراكبات ال
+
+124
+00:11:28,590 --> 00:11:35,390
+antirosigments مافيها ال iris انجل ممكن يعمل
+
+125
+00:11:35,390 --> 00:11:39,940
+physis physis بلبيسايسس بلبي ضمور العين زى الرجل
+
+126
+00:11:39,940 --> 00:11:44,460
+هذا اللى شوفناه قبل قليل يعنى هذا سايسس بلبي عينه
+
+127
+00:11:44,460 --> 00:11:50,440
+خربت خلاص لإن صار فيها نكروز داخل العين شايفين عين
+
+128
+00:11:50,440 --> 00:11:55,420
+هنا كيف وعين هنا كيف هنا لسه بدية التهيب واشي يعني
+
+129
+00:11:55,420 --> 00:11:59,060
+عبارة عن conjun device مش فاكره تكتر لكن هنا راحت
+
+130
+00:11:59,060 --> 00:12:04,170
+شوه على يوجر تراكت وعملتله ضمورهو عمى يعني physis
+
+131
+00:12:04,170 --> 00:12:09,190
+بلبي معناها blindness physis بلبي معناها blindness
+
+132
+00:12:09,190 --> 00:12:16,830
+عين ضامرة مافيش فيها ضغط طيب
+
+133
+00:12:16,830 --> 00:12:21,990
+الجلوكومه ليه الجلوكومه لأنه خربت الترابيخومشوار
+
+134
+00:12:21,990 --> 00:12:31,430
+اللي في anterior chamber angle ممكن لو زادت تصليله
+
+135
+00:12:31,430 --> 00:12:36,430
+كنايتسالريتنايتس يعني ممكن نصلّى ريتنا و الفيروس
+
+136
+00:12:36,430 --> 00:12:40,370
+هذا يعني لو اجي ناس تعافى ممكن نصلّى ريتنا مافيش
+
+137
+00:12:40,370 --> 00:12:46,690
+علاج طيب high retinitis اه فيه retinal necrosis
+
+138
+00:12:46,690 --> 00:12:53,290
+ذوبان للي اللي هو الشبكية high necrosis من
+
+139
+00:12:53,290 --> 00:12:56,850
+الريتنايتس بتاعة herpes zoster لازم نميز بين ال
+
+140
+00:12:56,850 --> 00:13:02,240
+zoster وبين ال simplex مع أنه اتنينيعني عيلة واحدة
+
+141
+00:13:02,240 --> 00:13:08,620
+لكن بتختلفوا في اللي هو الأعراض والعالمات خلصنا
+
+142
+00:13:08,620 --> 00:13:14,180
+اللي هو ال zooster لان حالي دي ال virus شرس اسمه
+
+143
+00:13:14,180 --> 00:13:19,320
+ال influenza virus مين منا كل عام الشتاء خاصة بقعد
+
+144
+00:13:19,320 --> 00:13:23,320
+صاب بال influenza ال influenza حقيقة ماقدرش اقول
+
+145
+00:13:23,320 --> 00:13:27,760
+انه من عيلة اللي هو ال herpes لأ لأ ال influenza
+
+146
+00:13:27,760 --> 00:13:30,060
+من orthomyxovirus
+
+147
+00:13:31,450 --> 00:13:37,550
+خلاص يعني احنا نكتفي بال .. بال .. بال herpes اللي
+
+148
+00:13:37,550 --> 00:13:43,170
+قولناه الآن زوستر كآخر ايش واحد من اللي هو عيلة ال
+
+149
+00:13:43,170 --> 00:13:49,330
+.. ال .. ال herpes خلاص الآن هنفش في عيلة جديدة اه
+
+150
+00:13:49,330 --> 00:13:55,110
+اللي هو Orthomyxoviruses Orthomyxoviruses و اللي
+
+151
+00:13:55,110 --> 00:13:59,770
+منها ال influenza single strand RNA
+
+152
+00:14:01,960 --> 00:14:07,780
+هذا كما كنا نقول عنه ال herpes double strand DNA
+
+153
+00:14:07,780 --> 00:14:13,700
+هذا single strand يعني فت واحد جيني والحمض النووي
+
+154
+00:14:13,700 --> 00:14:20,220
+RNA رايبو نيوكليك أسد مش DNA طيب انفلوب بايروس
+
+155
+00:14:20,220 --> 00:14:24,000
+يعني إيه انفلوب؟ إيه مظروف خارجي؟ بيهوا في أنا
+
+156
+00:14:24,000 --> 00:14:28,660
+عندي تلات أنواع من ال influenza virus influenza A
+
+157
+00:14:28,660 --> 00:14:30,100
+وB
+
+158
+00:14:32,050 --> 00:14:37,610
+ماهي الفرق بين ال a و ال b و ال c انفلونزا ايه
+
+159
+00:14:37,610 --> 00:14:41,970
+انفلونزا الطيور و كلنا احنا اسمها افين انفلونزا
+
+160
+00:14:41,970 --> 00:14:46,630
+افين يعني الطيور الحقيقة هذا يعني لا تشرح عنه كتير
+
+161
+00:14:46,630 --> 00:14:53,810
+لكن له sudden major mutations يعني له فترات سريعة
+
+162
+00:14:53,810 --> 00:14:59,190
+و قوية يعني بغير في ترتيبه و بصيب الطيور بصورة
+
+163
+00:14:59,190 --> 00:15:10,160
+خطيرةاللي هو ال virus A ال virus A طيب الان هو
+
+164
+00:15:10,160 --> 00:15:16,140
+اللي بصيب برضه الأبين الطيور بصيب ال swine او ال
+
+165
+00:15:16,140 --> 00:15:21,480
+swine اللي هو الخنازير ممكن تصيب الإنسان أحيانا
+
+166
+00:15:21,480 --> 00:15:27,060
+human و avian و swine لكن معروف ان هو في الأبين في
+
+167
+00:15:27,060 --> 00:15:33,670
+الطيورأكتر شيء ويله قدرة كبيرة على ال mutation على
+
+168
+00:15:33,670 --> 00:15:39,330
+القطرات وتغيير الجينات أكتر من اللي هو النوعية
+
+169
+00:15:39,330 --> 00:15:44,770
+التانية طيب هذه الفيروس تحت المايكسكوب الإلكتروني
+
+170
+00:15:44,770 --> 00:15:52,750
+طيب نشوف ال B ال A و ال C بصيبوا البشرة البشرة ال
+
+171
+00:15:52,750 --> 00:15:59,100
+B sequence while being in people يعني انتقلسورة
+
+172
+00:15:59,100 --> 00:16:03,880
+كبيرة بما يسعى بين الإنسان وليس الحيوانات ، لا
+
+173
+00:16:03,880 --> 00:16:09,280
+ينظر إلى الخنازير ولا ينظر إلى الطيور هو ليس لديه
+
+174
+00:16:09,280 --> 00:16:16,580
+طفرة لـ A نقطة اندرجورة بالـ Exchange وليس مختلفة
+
+175
+00:16:16,580 --> 00:16:21,840
+يعني ليس لديها مختلفات كثيرة وفروق كثيرة الـ C
+
+176
+00:16:21,840 --> 00:16:28,360
+أيضًا في الإنسانوهو بيعمل mild illness يعني مرضه
+
+177
+00:16:28,360 --> 00:16:34,980
+خفيف هو بيعملش epidemics اللي بيعمل epidemic ال B
+
+178
+00:16:34,980 --> 00:16:40,780
+epidemic يعني انه مستسع اسمه epidemic يعني وباء ال
+
+179
+00:16:40,780 --> 00:16:48,320
+وباء لل Bوالـ mutation للـ A الـ mutation للـ A
+
+180
+00:16:48,320 --> 00:16:54,300
+والـ C ميلد الـ C بصيب الإنسان بس بيعمل ميلد يعني
+
+181
+00:16:54,300 --> 00:16:57,860
+مش كتير بأثر على الإنسان عشان ايه احنا الآن بدنا
+
+182
+00:16:57,860 --> 00:17:02,460
+ندرس الـ B يعني هات الكلام دلوقت هيكون ايش على
+
+183
+00:17:02,460 --> 00:17:07,840
+الفيروس B الـ B ايش بيعمل في العين احنا ناس
+
+184
+00:17:07,840 --> 00:17:12,840
+افلومتري يعني عيونبعمل optic neuritis ضمور او
+
+185
+00:17:12,840 --> 00:17:17,640
+اتهاب العصب البطري وبعمل شلل بال extraocular
+
+186
+00:17:17,640 --> 00:17:25,640
+muscles extraocular muscle ballsy ballsy يعني
+
+187
+00:17:25,640 --> 00:17:32,740
+شلل في اللي هو ايش العضلات
+
+188
+00:17:32,740 --> 00:17:36,180
+الخارجية العين اللي هم ستة اربعة مستقيمة واثنين
+
+189
+00:17:36,180 --> 00:17:40,030
+مائلةacumulative abnormalities بيأثر على السيري
+
+190
+00:17:40,030 --> 00:17:44,350
+ماصل يعني بيأثر على ال accommodation اللى فى العين
+
+191
+00:17:44,350 --> 00:17:50,670
+ممكن يعمل مدريازيس لأنه يعني بيعمل خلل في اللى هو
+
+192
+00:17:50,670 --> 00:17:54,630
+sphincter في وكلي ماصل فال dialyzer بتغلبها وباك
+
+193
+00:17:54,630 --> 00:18:00,310
+اللى ديما تورم عصب البصري تورم عصب البصري وهذا
+
+194
+00:18:00,310 --> 00:18:05,210
+معروف بيجي من ارتفاع في ضغطاللي هو المخ increase
+
+195
+00:18:05,210 --> 00:18:08,450
+intracranial pressure يبقى إيش بيعمل الانفلوانزا
+
+196
+00:18:08,450 --> 00:18:12,510
+بيه optic neuritis palsy of extracranial muscles
+
+197
+00:18:12,510 --> 00:18:15,530
+بيأثر على أسنان ال muscle بيعمل abnormalities of
+
+198
+00:18:15,530 --> 00:18:18,870
+that accommodation بيأثر على اللي هو sphincter
+
+199
+00:18:18,870 --> 00:18:22,110
+pupillary muscle بضعفها فال director بتوسع اللي هو
+
+200
+00:18:22,110 --> 00:18:27,530
+الحدقة وبيعمل papilloma بيعمل papilloma تورم رأس
+
+201
+00:18:27,530 --> 00:18:35,510
+عصب مصري نتيجة الاتفاق داخل درجة العينبقولي بجانب
+
+202
+00:18:35,510 --> 00:18:39,490
+ذلك ان
+
+203
+00:18:39,490 --> 00:18:46,570
+ممكن انسان ينصاب في مثلا في ال B و بعدها ينصاب في
+
+204
+00:18:46,570 --> 00:18:53,290
+ال C وبالتالي لما يشفى من واحد يجع في التاني فلو
+
+205
+00:18:53,290 --> 00:18:58,350
+يعني الذات البرد او ال influenza و بعد ما يشفى
+
+206
+00:18:58,350 --> 00:19:04,520
+يصير contact او contract يعني يلتقط infectionAgain
+
+207
+00:19:04,520 --> 00:19:08,680
+من فيروس تاني زي و لا يتبقى الكورونا الآن ال فيروس
+
+208
+00:19:08,680 --> 00:19:12,740
+هذا بيقولك انه بيشفى من الكورونا وبعد شهرين تلاتة
+
+209
+00:19:12,740 --> 00:19:16,020
+بترجعله اللي بيرجعله مش نفس الفيروس اللي عمله
+
+210
+00:19:16,020 --> 00:19:21,460
+antibody لأ فيروس محور وعمله طفرة و غير في شكله
+
+211
+00:19:21,460 --> 00:19:26,640
+والانفلوانزا كل سنة ابتدي الانفلوانزا في فيروس
+
+212
+00:19:26,640 --> 00:19:30,620
+جديد يعني اللي اتطعم السنة هذه او اصيب السنة هذه
+
+213
+00:19:30,620 --> 00:19:35,610
+السنة الجاية ممكن يجي فيروسجديد وماينفعلوش اللقاح
+
+214
+00:19:35,610 --> 00:19:38,490
+او التطعيم اللي هو عمله او ال antibodies اللي
+
+215
+00:19:38,490 --> 00:19:44,630
+اكتسبها من مرض هذا العام طيب ال general clinical
+
+216
+00:19:44,630 --> 00:19:48,170
+disease ايش general يعني اقصر فيها ال general اللي
+
+217
+00:19:48,170 --> 00:19:54,610
+هو عامة مش في العين العين خلصناها الآن خمسة العامة
+
+218
+00:19:54,610 --> 00:19:59,430
+fever و headache وmyalgia اي واحد في ال forward
+
+219
+00:19:59,430 --> 00:20:04,450
+بيقولك انا عضلاتك بتجعنيوصودة علي أطاق وسخونة
+
+220
+00:20:04,450 --> 00:20:10,650
+تقريبا 39 درجة هذه الأعراض
+
+221
+00:20:10,650 --> 00:20:17,550
+تبدأ بصورة حادة تتقدم بسرعة يعني من تالت يوم تجي
+
+222
+00:20:17,550 --> 00:20:18,410
+مرمي في ال fresh
+
+223
+00:20:22,500 --> 00:20:26,740
+أو أصابعات البرد في فيروس اسمه common cold virus
+
+224
+00:20:26,740 --> 00:20:30,260
+هذا أضعف من هي لكن ال influenza لا ترميه في الأرض
+
+225
+00:20:30,260 --> 00:20:36,320
+الشباب بيتعافوا
+
+226
+00:20:36,320 --> 00:20:43,580
+after about a week بعد أسبوع الشباب بيرجع لعب كورة
+
+227
+00:20:43,580 --> 00:20:49,410
+و بيروح الجامعة عادي لكن ال old ageاللي هم الناس
+
+228
+00:20:49,410 --> 00:20:55,230
+اللي بعد ال 50 و ال 60 او الناس ال debilitated
+
+229
+00:20:55,230 --> 00:21:01,850
+الناس الضعاف مناعيا ممكن انه يصير معهم مضاعفات زي
+
+230
+00:21:01,850 --> 00:21:06,230
+cardio pulmonary complications يعني ال pulmonary
+
+231
+00:21:06,230 --> 00:21:11,530
+الرئتين زي ال pneumonia وال cardio القلب يعني ممكن
+
+232
+00:21:11,530 --> 00:21:17,010
+تصير مضاعفات في القلب زي تضخم القلب مثلا زي اضطراب
+
+233
+00:21:17,010 --> 00:21:22,610
+القلبفشل القلب وممكن نيومونيا وبرونكايتس وبرونكو
+
+234
+00:21:22,610 --> 00:21:28,630
+نيومونيا اللى هو جهاز التنفسى مما قد يؤدي الى
+
+235
+00:21:28,630 --> 00:21:35,970
+الوفاة الفوزة الأسبانية اللى اجت في 1918 في اوروبا
+
+236
+00:21:35,970 --> 00:21:39,830
+1918 يعني عندما جمت الحرب العالمية الأولى قالوا
+
+237
+00:21:39,830 --> 00:21:44,310
+انها قتلت خمسين الى سبعين مليون انسان خمسين الى
+
+238
+00:21:44,310 --> 00:21:51,380
+سبعينمليون إنسان يعني الفروانزا في كبار السن خطيرة
+
+239
+00:21:51,380 --> 00:21:55,040
+وفي الناس المرضى أمراض مزمنة الشباب يعني كنتوا
+
+240
+00:21:55,040 --> 00:22:00,680
+بتتحملوها لكن كبار السن ممكن تفتك فيهم نرجع
+
+241
+00:22:00,680 --> 00:22:04,700
+للأوكيلار مانفستيشن ان اتكلمنا عنها الان كلام
+
+242
+00:22:04,700 --> 00:22:11,480
+مختصر نرجع لها كودركتروائتس لانفروانزا وايراتسالذي
+
+243
+00:22:11,480 --> 00:22:18,220
+هو الذهاب القزحى وانترستيشيا كيروتايتس تعمل داكرو
+
+244
+00:22:18,220 --> 00:22:23,020
+أدينايتس يعني ادهاب غدة الدم الرئيسية داكرو
+
+245
+00:22:23,020 --> 00:22:28,320
+أدينايتس معروفة وين غدة الدم الرئيسة في العين ممكن
+
+246
+00:22:28,320 --> 00:22:33,220
+تعمل مكولار هيموريج مكولار هيموريج يعني نزيف على
+
+247
+00:22:33,220 --> 00:22:38,900
+المكولة وهذا بيعمل عمى وممكن يعمل star
+
+248
+00:22:41,200 --> 00:22:50,100
+basculopathy يعني تعملي على المكيولة عبارة عن يعني
+
+249
+00:22:50,100 --> 00:22:56,060
+ترسب ضهني نجمي يعني بشكل النجمة يعني يكون هاي
+
+250
+00:22:56,060 --> 00:23:04,320
+المكيولة هيك هي أنا المكيولة اه وحواليها زي شعار
+
+251
+00:23:04,320 --> 00:23:11,790
+يعني الشمس هيك من اللبد الأصفر ترسب ايهدهني ترتب
+
+252
+00:23:11,790 --> 00:23:19,130
+دهني حول ايه هاي الماكولا هنا وهنا limit star
+
+253
+00:23:19,130 --> 00:23:27,330
+وزكرو بكي وهذا نتيجة لهو الفيروس الانفلونزا ومع
+
+254
+00:23:27,330 --> 00:23:32,730
+ذلك الاتناكس ممكن في ناس ضعاف كبار السن تعمله
+
+255
+00:23:32,730 --> 00:23:39,480
+اتهاب شبكي وتعمله نظيف وتعمله اذيمةتورم على
+
+256
+00:23:39,480 --> 00:23:43,480
+الشبكات الصبح هذه مابتصيرش حقيقة في كل ال
+
+257
+00:23:43,480 --> 00:23:47,720
+influenza ونادر يعني ماتصير في كبار السن و المرضى
+
+258
+00:23:47,720 --> 00:23:54,860
+خاصة مرضى ال aids خاصة مرضى ال aids طيب هذه الصورة
+
+259
+00:23:54,860 --> 00:24:01,670
+بتبريك popular disease of influenza virusاللي هو
+
+260
+00:24:01,670 --> 00:24:04,790
+الحمر هذا congenitivitis وممكن scleritis
+
+261
+00:24:04,790 --> 00:24:10,670
+وبسكليريتس الحمر هذا وبعدين الكيروتيتس والايريتس
+
+262
+00:24:10,670 --> 00:24:14,290
+الريدو سايكلاتس اللي هو دوا العين طيب انا حابب اني
+
+263
+00:24:14,290 --> 00:24:20,150
+اتوقف عند هذه الشريحة 277 على ان اكمل ان شاء الله
+
+264
+00:24:20,150 --> 00:24:24,450
+ربما تكون المحاضرة جاية اخر محاضرة او قبل الأخيرة
+
+265
+00:24:24,450 --> 00:24:29,730
+يعني انا مش عارف يعني التسهيلإن تكون هي الأخيرة أو
+
+266
+00:24:29,730 --> 00:24:32,790
+قبل الأثيرة فأسأل الله أن ربنا يتمم إلينا وإلكم
+
+267
+00:24:32,790 --> 00:24:36,950
+على خير و تشوفوا نجاح الباهر والسلام عليكم ورحمة
+
+268
+00:24:36,950 --> 00:24:37,490
+الله
+
diff --git a/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/T_PYo8LaoV4.srt b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/T_PYo8LaoV4.srt
new file mode 100644
index 0000000000000000000000000000000000000000..08706989a0c4f651005292e8848ec0de43387a85
--- /dev/null
+++ b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/T_PYo8LaoV4.srt
@@ -0,0 +1,1411 @@
+1
+00:00:00,560 --> 00:00:06,120
+بسم الله الرحمن الرحيم الحمد لله وكفى وأصلي و
+
+2
+00:00:06,120 --> 00:00:12,600
+أسلم على النبي المصطفى بناتي في المستوى الثالث في
+
+3
+00:00:12,600 --> 00:00:16,500
+قسم البصريات الطبية السلام عليكم ورحمة الله 
+
+4
+00:00:16,500 --> 00:00:22,980
+وبركاته نبدأ اليوم محاضرة ثامنة وعشرين في 
+
+5
+00:00:22,980 --> 00:00:29,670
+chapter fourteen حول Ocular Viral Infections أي
+
+6
+00:00:29,670 --> 00:00:34,650
+الفيروسات التي تصيب العين وما أكثر الفيروسات التي
+
+7
+00:00:34,650 --> 00:00:42,650
+تصيب العين وتؤدي إلى نقص أو فقد الوظيفة البصرية 
+
+8
+00:00:42,650 --> 00:00:49,290
+للعين يقول إن الفيروسات 
+
+9
+00:00:49,290 --> 00:00:55,800
+في العين هي كثيرة ومعقدة يعني ليست كما تصور البعض 
+
+10
+00:00:55,800 --> 00:01:01,380
+أنها قليلة لأ هي كثيرة ومتنوعة في أشكالها وفي
+
+11
+00:01:01,380 --> 00:01:06,500
+أسمائها لِيش؟ لأنها معرضة على الـ external world 
+
+12
+00:01:06,500 --> 00:01:12,640
+معرضة على العالم الخارجي تدخل فيها بكتيريا فيروسات
+
+13
+00:01:12,640 --> 00:01:19,480
+غبار يعني أجسام غريبة وهي محمية بـ  cellular membrane
+
+14
+00:01:19,480 --> 00:01:26,200
+وـ epithelium swans المتحولة أو في الفرنسية وبالتالي 
+
+15
+00:01:26,200 --> 00:01:31,960
+أن يعني الوقاية محدودة مش قوية كثير خاصة ضد الـ
+
+16
+00:01:31,960 --> 00:01:37,080
+airborne particulate matter اللي هو الأجسام الغريبة 
+
+17
+00:01:37,080 --> 00:01:43,420
+اللي يحملها الهواء يحملها الهواء أجسام غريبة يعني
+
+18
+00:01:43,420 --> 00:01:48,560
+ممكن تكون في الهواء أو في الأصابع أو حتى الـ
+
+19
+00:01:48,560 --> 00:01:53,700
+contact lenses اللي إحنا مستخدمينها أو حتى يعني إذا
+
+20
+00:01:53,700 --> 00:01:58,720
+ بالأظافر بتاعة الأصابع يعني ممكن جدا واحد هو بيركب 
+
+21
+00:01:58,720 --> 00:02:03,500
+العدسة اللاصقة يجرح القرنية بتاعته بطرف أظفره خاصة 
+
+22
+00:02:03,500 --> 00:02:12,840
+اللي عندهم أظافر طويلة يبقى الـ external اللي من
+
+23
+00:02:12,840 --> 00:02:19,060
+الخارج هو الأكثر ليه دخول العين من الـ external لكن الـ 
+
+24
+00:02:19,060 --> 00:02:26,300
+internal آه عن طريق الدم آه عن طريق الـ blood 
+
+25
+00:02:26,300 --> 00:02:29,580
+vessels وعن طريق الدم اسمها Internal اللي هو 
+
+26
+00:02:29,580 --> 00:02:33,260
+Entry Internal Entry عن طريق الـ blood vessels يعني
+
+27
+00:02:33,260 --> 00:02:37,320
+عن طريق الدم شيء بيكون في الدم فيروسات ممكن تلج 
+
+28
+00:02:37,320 --> 00:02:45,420
+إلى العين طيب تصنيف الفيروسات عموما وبعدين نخش في 
+
+29
+00:02:45,420 --> 00:02:49,940
+غُلفة العين الفيروسات هي أنا بقول أصغر المخلوقات
+
+30
+00:02:49,940 --> 00:02:53,610
+التي خلق الله عز وجل لقيت أن أنا في قصب الـ
+
+31
+00:02:53,610 --> 00:02:58,010
+nanometer طب إيش هو الـ nanometer؟ الـ nanometer واحد
+
+32
+00:02:58,010 --> 00:03:07,070
+على الألف micron واحد على الألف micro mil micro mil 
+
+33
+00:03:07,070 --> 00:03:19,710
+micro mil طيب الآن الـ micron هذا يساوي واحد على 
+
+34
+00:03:19,710 --> 00:03:28,570
+الألف من إيش؟ من الـ millimeter الـ millimeter كم نانو
+
+35
+00:03:28,570 --> 00:03:37,750
+متر؟ واحد على المليون واحد على ستة أصفار واحد على 
+
+36
+00:03:37,750 --> 00:03:41,530
+مليون نانو متر نانو 
+
+37
+00:03:43,270 --> 00:03:51,190
+m nanometer تساوي واحد على المليون من المليمتر وإحنا 
+
+38
+00:03:51,190 --> 00:03:58,130
+عارفين المليمتر واحد على الألف من المتر من المتر 
+
+39
+00:03:58,130 --> 00:04:06,830
+يعني هذه ستة أصفار هيك ستة أصفار يبقى الآن الـ الـ الـ الـ 
+
+40
+00:04:06,830 --> 00:04:12,290
+الفيروسات تقاس بالنانومتر يعني هتبقى لأ مش فاش بالعين 
+
+41
+00:04:12,290 --> 00:04:20,530
+يعني من عشرين نانو متر إلى مائتين نانو متر تقريبا 
+
+42
+00:04:20,530 --> 00:04:23,730
+يعني الفيروسات سوية إلى عشرين في تلاتين أربعين 
+
+43
+00:04:23,730 --> 00:04:29,940
+خمسين ستين لما يصل لـ مائتين نانو متر أكبر فيروس هذه 
+
+44
+00:04:29,940 --> 00:04:36,700
+الفيروسات Obligate Intracellular Parasites يعني 
+
+45
+00:04:36,700 --> 00:04:43,680
+هذه طفيلية مائة في المائة لا تعيش أبدا خارج خلايا
+
+46
+00:04:43,680 --> 00:04:48,800
+المضيف أو الإنسان أو الحيوان Obligate يعني إجبارية 
+
+47
+00:04:48,800 --> 00:04:53,460
+لا تعيش ما فيش عندها قدرة زي البكتيريا أن تعيش في 
+
+48
+00:04:53,460 --> 00:04:59,540
+الماء وتعيش في التربة لأ Obligate هي حقيقة إحنا
+
+49
+00:04:59,540 --> 00:05:08,180
+هنجيب صورتها لها جينيتي كود رمز جيني آه لكن غير 
+
+50
+00:05:08,180 --> 00:05:11,660
+قادرة على الـ reproduction زي البكتيريا تنقسم ثنائي
+
+51
+00:05:11,660 --> 00:05:16,880
+بسيط في الشلها ولا تتكاثر إلا داخل الخلية الحية
+
+52
+00:05:16,880 --> 00:05:25,330
+للإنسان أو الحيوان آه يبقى هيتستغل وجودها في خلايا 
+
+53
+00:05:25,330 --> 00:05:33,150
+العائل لتمد نفسها بالطاقة اللي هو التغذية اللازمة 
+
+54
+00:05:33,150 --> 00:05:37,030
+لوازم غذائية اللازمة حتى تعمل replication أو تكاثر 
+
+55
+00:05:37,030 --> 00:05:44,350
+حتى تعمل تكاثر بيقول أن كمان حاجة تختلف عن
+
+56
+00:05:44,350 --> 00:05:49,390
+بكتيريا اللي قادرة أن تعيش يعني free في بعض 
+
+57
+00:05:49,390 --> 00:05:58,180
+الأحيان الشيطان والولايات تحتوي على حمضيين نوويين
+
+58
+00:05:58,180 --> 00:06:04,740
+بل على أحدهما إما DNA أو RNA not both يعني واحد 
+
+59
+00:06:04,740 --> 00:06:09,040
+منهم بس يبقى شكل هذه الفيروسات فيها DNA فيروس وفي 
+
+60
+00:06:09,040 --> 00:06:14,160
+RNA فيروس لكن البكتيريا إيش فيها DNA و RNA زي خلية 
+
+61
+00:06:14,160 --> 00:06:19,540
+الإنسان من حيث احتوائها على له نوعين من الأحماض
+
+62
+00:06:19,540 --> 00:06:26,560
+النووية طيب كيف يعني نقسم الفيروسات أو نصنف
+
+63
+00:06:26,560 --> 00:06:31,160
+الفيروسات حقيقة فيه عدة طرق لتصنيف الفيروسات في 
+
+64
+00:06:31,160 --> 00:06:41,600
+تصنيف حسب اللي هو المضيف هل هي مثلا للإنسان بس ولا 
+
+65
+00:06:41,600 --> 00:06:46,780
+للحيوان بس ولا للنبات بس ولا حتى للبكتيريا ولا حتى 
+
+66
+00:06:46,780 --> 00:06:51,340
+للفطريات في فيروسات لها كثير عوائل وفي فيروسات 
+
+67
+00:06:51,340 --> 00:06:57,000
+لها عائل واحد بس يبقى host range يعني في host 
+
+68
+00:06:57,000 --> 00:07:04,940
+wide range وفي host narrow range يعني ضيق كل ما 
+
+69
+00:07:04,940 --> 00:07:09,480
+كان بيصيب إنسان حيوان نبات بكتيريا فطريات زي هيك 
+
+70
+00:07:09,480 --> 00:07:14,260
+هذه بيسميها wide host range viruses بس كان بيصيب 
+
+71
+00:07:14,260 --> 00:07:18,040
+واحد منهم بس أو اثنين بيقول narrow host range 
+
+72
+00:07:18,040 --> 00:07:24,280
+virus التصنيف الثاني حسب المرض في شيء بيعمل 
+
+73
+00:07:24,280 --> 00:07:28,500
+influenza وفي شيء بيعمل في الجلد وفي شيء بيعمل في
+
+74
+00:07:28,500 --> 00:07:35,880
+العين وفي شيء بيعمل في الدماغ وفي شيء بيعمل في اللي 
+
+75
+00:07:35,880 --> 00:07:42,640
+هو البقن وهاكذا يعني حسب الـ disease organ type 
+
+76
+00:07:42,640 --> 00:07:47,320
+حسب العضو يعني في فيروسات بتصيب عضو وفي فيروسات 
+
+77
+00:07:47,320 --> 00:07:53,560
+بتصيب عدة أعضاء يعني فيروس نقص المناعة hiv hiv اللي 
+
+78
+00:07:53,560 --> 00:08:00,920
+هو بتاع الإيدز h i v هذا معروف أن صح بيخش منه
+
+79
+00:08:00,920 --> 00:08:05,820
+الأعضاء التناسلية لكن بينتشر في كل جسم الإنسان و
+
+80
+00:08:05,820 --> 00:08:11,020
+بيصيب كثير organs بينما مثلا التقيح اللي بيصيب بطن
+
+81
+00:08:11,020 --> 00:08:15,020
+الرجل تقرح هذه فيروسات هذه أو التقرح اللي بتكون
+
+82
+00:08:15,020 --> 00:08:19,350
+في الجلد يعني لو حطيناها هو ما حطيناها بتنمو إلا على 
+
+83
+00:08:19,350 --> 00:08:24,410
+الجلد بس خلاص الـ virus of influenza مخصص للصدر
+
+84
+00:08:24,410 --> 00:08:29,270
+لجهاز التنفسي بيعملش في أي مكان ثاني بينما فيه 
+
+85
+00:08:29,270 --> 00:08:33,530
+في فيروسات بتأثر على أكثر من عضو هذه تصنيف ثالثة
+
+86
+00:08:33,530 --> 00:08:39,150
+التصنيف الرابع mode of transmission كيف ينتقل كثير 
+
+87
+00:08:39,150 --> 00:08:43,650
+من الفيروسات تنتقل عن طريق السعال والكحة في
+
+88
+00:08:43,650 --> 00:08:47,270
+في فيروسات عن طريق الملامسة في فيروسات عن طريق
+
+89
+00:08:47,270 --> 00:08:52,930
+الممارسة الجنسية يعني مش كل الفيروسات لها طريقة 
+
+90
+00:08:52,930 --> 00:08:58,290
+انتقال واحدة يعني كثير من الفيروسات لها طريقة أو 
+
+91
+00:08:58,290 --> 00:09:06,050
+طريقتين وفي يعني بس طريقة واحدة في فيروسات تسمى 
+
+92
+00:09:06,050 --> 00:09:10,420
+حسب الـ discoverers اللي اكتشفوها وهم في الغرب
+
+93
+00:09:10,420 --> 00:09:15,440
+بيصيحوا كثير يعني بيحبوا أن يكرموا المخترعين أو
+
+94
+00:09:15,440 --> 00:09:23,340
+المكتشفين فبيسموا اللي هي المكتشف على اسمه يبقى
+
+95
+00:09:23,340 --> 00:09:31,400
+مكتشف حسب اسم المكتشف آخر شيء حسب اللي هو nucleic
+
+96
+00:09:31,400 --> 00:09:37,080
+acid mRNA أو DNA يبقى لو قلنا ما هي طرق تصنيف 
+
+97
+00:09:37,080 --> 00:09:43,500
+البكتيريا حسب اللي هو المدى بتاع المضيف وحسب المرض
+
+98
+00:09:43,500 --> 00:09:48,500
+وحسب العضو اللي يصيبه الفيروس وحسب طريقة الانتقال
+
+99
+00:09:48,500 --> 00:09:54,620
+وممكن حسب المكتشف لهذا الفيروس أو حسب الخارطة
+
+100
+00:09:54,620 --> 00:09:59,440
+الجينية DNA أو RNA طيب في الـ classification 
+
+101
+00:10:02,230 --> 00:10:08,450
+في الآن شكلت لجنة committee لتاکسونومی
+
+102
+00:10:08,450 --> 00:10:13,170
+للتسمية يعني ما خلوهاش عشوائية لأ شكلوا لجنة 
+
+103
+00:10:13,170 --> 00:10:18,450
+دولية international دولية committee تكون هذه taxonomy
+
+104
+00:10:18,450 --> 00:10:24,750
+للتسمية وهذه اشتغلت على الجينوم الجينوم الخارطة 
+
+105
+00:10:24,750 --> 00:10:32,310
+الجينية كل إنسان حي أو حيوان حي أو نبات حي أو فئران
+
+106
+00:10:32,310 --> 00:10:37,410
+أو أوثانيات أو حتى الذباب والسرسير والبعوض
+
+107
+00:10:37,410 --> 00:10:43,730
+والبكتيريا والفطريات والفيروسات لها جينوم جينوم 
+
+108
+00:10:43,730 --> 00:10:46,830
+يبقى لها خِلطة جينية مدى أنك تقدر تعيش في الـ
+
+109
+00:10:46,830 --> 00:10:52,350
+scatter إذا لها جينوم الجينوم هذا إما يكون من حبل
+
+110
+00:10:52,350 --> 00:10:59,410
+DNA أو من حبل RNA يبقى الآن حول صنفه جديد قالوا 
+
+111
+00:10:59,410 --> 00:11:07,170
+نسميهما إما single 
+
+112
+00:11:07,170 --> 00:11:13,930
+strand أو double strand بيقص double double يعني
+
+113
+00:11:13,930 --> 00:11:20,890
+اثنين أو single strand حبل واحد يبقى حبل من الـ DNA
+
+114
+00:11:20,890 --> 00:11:28,880
+أو الـ RNA وحيد single وحبل ملتوي من DNA أو RNA
+
+115
+00:11:28,880 --> 00:11:33,360
+المهم أن حبلين يعني زي هيك يعني هاي صورة هاي
+
+116
+00:11:33,360 --> 00:11:39,400
+double strand هاي strand هيك هاي strand وهاي
+
+117
+00:11:39,400 --> 00:11:43,340
+strand ملتفة عليه كمان هاي اثنين يبقى كيف هيصار
+
+118
+00:11:43,340 --> 00:11:49,500
+double strand طيب هذا هي وهيك الحبل هذا مبين أن 
+
+119
+00:11:49,500 --> 00:11:59,130
+وحيد وهذا وحيد سواء DNA أو RNA كويس يبقى هذا one SS 
+
+120
+00:11:59,130 --> 00:12:08,870
+و هذا ds ليش ds double يعني مضاعف مزدوج 
+
+121
+00:12:08,870 --> 00:12:15,110
+يبقى إما single strand أو double strand الـ 
+
+122
+00:12:15,110 --> 00:12:20,520
+double strand سموّه pair مجوز مدوس اثنين يعني الـ
+
+123
+00:12:20,520 --> 00:12:25,400
+single ss سموّه single يعني فرداني يعني لحاله 
+
+124
+00:12:25,400 --> 00:12:30,340
+واحد بس أو unpaired single أو unpaired هنقضبهم أو
+
+125
+00:12:30,340 --> 00:12:36,400
+paired هاي واحدة منهم طيب
+
+126
+00:12:36,400 --> 00:12:42,040
+ال وين
+
+127
+00:12:42,040 --> 00:12:45,200
+إحنا آه
+
+128
+00:12:45,950 --> 00:12:55,150
+بقول إما ss أو ds عرفناها هذه طيب بقول حاجة ثانية
+
+129
+00:12:55,150 --> 00:13:07,630
+plus أو minus يعني سلبي موجب plus أو سلبي طب يعني
+
+130
+00:13:07,630 --> 00:13:14,630
+إيش موجب أو سلبي بقول لك حسب الاشعار الكهربائي الـ
+
+131
+00:13:14,630 --> 00:13:20,830
+polarity آه آه والـ direction of reading بيقول في
+
+132
+00:13:20,830 --> 00:13:27,110
+الـ direction of reading الموجب الموجب غالبا بيكون
+
+133
+00:13:27,110 --> 00:13:34,630
+رأسي اسمه sense والثاني الـ antisense بيكون له أفقي 
+
+134
+00:13:34,630 --> 00:13:43,370
+بيكون أفقي كيف يعني هاي الرأسي sense بس كان الأحبال 
+
+135
+00:13:43,370 --> 00:13:50,750
+هذه النووية كانت رأسية صف هيك رأسية بيقول عنها
+
+136
+00:13:50,750 --> 00:14:00,530
+موجبة plus أو sense بس كانها أفقية زي هيك مصفوفة هيك
+
+137
+00:14:00,530 --> 00:14:04,850
+الأحبال النووية هذه بيقول عنها antisense أو minus
+
+138
+00:14:04,850 --> 00:14:13,690
+antisense أو minus طيب هي صورة للفيروس إحنا أخذنا
+
+139
+00:14:13,690 --> 00:14:19,950
+قبل هيك الخلية اللي هي إيش البكتيريا وإنتحنّا
+
+140
+00:14:19,950 --> 00:14:24,970
+فيها في الـ mid term الآن الخلية البكتيرية الـ virus 
+
+141
+00:14:24,970 --> 00:14:31,210
+هي الـ viral cell شوف تتكون من إيش تتكون نبدأ من
+
+142
+00:14:31,210 --> 00:14:36,290
+برا شويكات بروتينية صغيرة هذه اسمها envelope
+
+143
+00:14:36,290 --> 00:14:42,530
+protein اللي هو إيش الغطاء أو الغشاء كل
+
+144
+00:14:42,530 --> 00:14:47,350
+واحد من هدولة زي شوك الصبر الصغير فيه خالص اللي
+
+145
+00:14:47,350 --> 00:14:52,490
+لما واحد بصيبه وغز في إيده هذا ليه؟ عشان يشبك في
+
+146
+00:14:52,490 --> 00:14:57,910
+إيش؟ في الأسطح يعني هاي سطح مثلا لإنسان أسابوخاطي
+
+147
+00:14:57,910 --> 00:15:04,970
+مثلا إجا الفيروس هيك دج شوكة صغيرة فيه بسيك
+
+148
+00:15:04,970 --> 00:15:13,330
+envelope بروتين زوائد بروتينية بعدين الـ pink هذا
+
+149
+00:15:13,330 --> 00:15:18,990
+الوردي الـ envelope غش envelope هو اللي هو الغشاء
+
+150
+00:15:18,990 --> 00:15:24,910
+أو الغطاء envelope يعني نحط رسالة في المظروف
+
+151
+00:15:24,910 --> 00:15:30,590
+بنسميه envelope رسالة بيحفظها الـ envelope وهذه
+
+152
+00:15:30,590 --> 00:15:34,670
+الخلية البروسية بيحفظها الـ envelope يبقى هذا
+
+153
+00:15:34,670 --> 00:15:41,480
+الوردي اسمه envelope طيب من جوه الـ envelope في شيء
+
+154
+00:15:41,480 --> 00:15:45,840
+اسمه segment أو segment segment اللي هو هذه
+
+155
+00:15:45,840 --> 00:15:52,080
+الحلقات شوف هذا يعني جدار داخل envelope حامي و
+
+156
+00:15:52,080 --> 00:16:00,620
+واقي اسمه segment segment هاي هذا segment هذا إيش
+
+157
+00:16:00,620 --> 00:16:06,830
+segment فهذا إيش بيظل بيظل غشاء خارجي للحبل النووي
+
+158
+00:16:06,830 --> 00:16:12,590
+اسمه نيوكليو كابسيل nucleocapsid اللي هو هذا هذا
+
+159
+00:16:12,590 --> 00:16:17,990
+اللي بيحيط في الحبل النووي هذا السلسل شكل nucleo
+
+160
+00:16:17,990 --> 00:16:23,450
+capsid إيش بيظل الحبل النووي viral genome هذا
+
+161
+00:16:23,450 --> 00:16:28,510
+الحبل النووي اللي عمل هيك اه genome اسمه genome
+
+162
+00:16:30,380 --> 00:16:34,440
+يعني إيش وجود الذينات فيه ملاحظين ما جالش nucleus
+
+163
+00:16:34,440 --> 00:16:39,520
+لأ لأن هذا مش nucleus ولا علها nuclear membrane
+
+164
+00:16:39,520 --> 00:16:46,900
+لأ لأ هذه بس مجرد حبل نووي و بس طبعت أنا إن الصورة
+
+165
+00:16:46,900 --> 00:16:51,640
+هذه أو نقلت أنا خصوصي الكهانة عشان إن تأخذوا بالكم 
+
+166
+00:16:51,640 --> 00:17:01,440
+منها يا بناتي طيب الآن سؤال كيف يدخل الفيروس و
+
+167
+00:17:01,440 --> 00:17:07,920
+تكاتر داخل جسم الإنسان viral entry أنت دخول يعني
+
+168
+00:17:07,920 --> 00:17:14,360
+and replication يعني تكاتر بقول إن يتم الـ viral
+
+169
+00:17:14,360 --> 00:17:24,010
+entry في العائل أو في الإنسان عبر الجلد غالبا اه بس
+
+170
+00:17:24,010 --> 00:17:28,850
+الجلد هذا لأنه لكن ممكن عبر الغشاء الغشاء المخاطي
+
+171
+00:17:28,850 --> 00:17:33,370
+مبطن مثلا لجهاز 
+
+172
+00:17:33,370 --> 00:17:39,050
+تنفسي غشاء مخاطي مبطن لأجهزة تناثولية أو يعني
+
+173
+00:17:39,050 --> 00:17:44,770
+الأجهزة الهضمى مثلا يبقى المهم سواء skin جلد
+
+174
+00:17:44,770 --> 00:17:48,670
+اكتبوا هنا or mucous
+
+175
+00:17:50,750 --> 00:18:03,070
+mucous membrane membrane mucous membrane mucous
+
+176
+00:18:03,070 --> 00:18:10,410
+membrane mucous membrane mucous
+
+177
+00:18:10,410 --> 00:18:12,870
+membrane mucous membrane mucous membrane mucous
+
+178
+00:18:12,870 --> 00:18:13,830
+membrane mucous membrane mucous membrane mucous
+
+179
+00:18:13,830 --> 00:18:13,950
+membrane mucous membrane mucous membrane mucous
+
+180
+00:18:13,950 --> 00:18:14,910
+membrane mucous membrane mucous membrane mucous
+
+181
+00:18:14,910 --> 00:18:22,250
+membrane mucous membrane mucous membrane تدخل عبر الـ
+
+182
+00:18:22,250 --> 00:18:29,090
+vector bites لدغات الحشرات مثلا البوضة مثلا
+
+183
+00:18:29,090 --> 00:18:32,350
+الجبابة
+
+184
+00:18:32,350 --> 00:18:37,230
+في أنواع من اللي هو الحشرات في أفريقيا في
+
+185
+00:18:37,230 --> 00:18:43,270
+الاستوائيات اه كتيرة بتدخل اللي هو زي ما يدخل
+
+186
+00:18:43,270 --> 00:18:47,130
+ملاريا مثلا في جسم الإنسان البروز برضه بتحمل بعض
+
+187
+00:18:47,670 --> 00:18:55,490
+اللي هو الحشرات لذلك الحشرات واحدة هذه بتدخل
+
+188
+00:18:55,490 --> 00:19:03,530
+الفيروس اتنين الـ abrasions كشوت أو خدوش يعني مثلا
+
+189
+00:19:03,530 --> 00:19:07,850
+القرنية السريمة مش سهل يدخلها الفيروس لكن لو
+
+190
+00:19:07,850 --> 00:19:13,350
+إنكشفت الإبشينة بتاعها بدخلها اه والـ abrasions في
+
+191
+00:19:13,350 --> 00:19:18,410
+الجلد حتى لو الواحد إنكشفت أو انجرح في إيد و
+
+192
+00:19:18,410 --> 00:19:22,710
+افريقلي أو bianidles
+
+193
+00:19:22,710 --> 00:19:27,830
+الإبرة
+
+194
+00:19:27,830 --> 00:19:35,610
+الطبية مثلا لو احنا ضربنا واحد في aids حقنا بالإبرة
+
+195
+00:19:35,610 --> 00:19:44,510
+وبعدها ضربنا واحد سليم بالإبرة نفسها ساعة الإبرة
+
+196
+00:19:44,510 --> 00:19:48,970
+نقلت من المريض الفيروس الـ AIDS الى السليم via
+
+197
+00:19:48,970 --> 00:19:54,670
+needles وقلنا عبر الـ microsal surfaces أو الـ
+
+198
+00:19:54,670 --> 00:19:58,490
+membranes هذا اللي قلناه جاب شوية mm عبر الـ skin
+
+199
+00:19:58,490 --> 00:20:02,290
+أو عبر الـ mucous membranes إيه المبطنة للجهاز
+
+200
+00:20:02,290 --> 00:20:05,330
+التنفسي المبطنة للجهاز الهضمي المبطنة للجهاز
+
+201
+00:20:05,330 --> 00:20:10,470
+التناسوي كل سبحان الله مغلف بأجهزة مخاطية حامية
+
+202
+00:20:10,470 --> 00:20:15,810
+فإذا إجا الفيروس على الإشياء المخاطي ودخل ممكن جدا
+
+203
+00:20:15,810 --> 00:20:23,730
+إن يدخل ويرج إلى الدم مثلا طيب بقول إن الـ virus
+
+204
+00:20:23,730 --> 00:20:30,970
+بتدخل الـ جسم عمر قرق مختلفة حسب الـ outer covering
+
+205
+00:20:30,970 --> 00:20:37,130
+حسب الغطاء الخارجي والـ virus متخصصة في دخولها مش
+
+206
+00:20:37,130 --> 00:20:42,270
+يعني لأ اللي يعني رايح الجهاز العصبي عارف حاله
+
+207
+00:20:42,270 --> 00:20:47,100
+رايح وإيه الـ receptors مستقبلات في الجهاز العصبي
+
+208
+00:20:47,100 --> 00:20:51,240
+واللي رايح على الجهاز التنفسي إله مستقبلات في
+
+209
+00:20:51,240 --> 00:20:54,680
+الجهاز التنفسي واللي رايح على الجهاز التناثوري إله
+
+210
+00:20:54,680 --> 00:20:57,840
+مستقبلات لو راحت الـ influenza على الجهاز التناثوري
+
+211
+00:20:57,840 --> 00:21:01,140
+مابتعملش حاجة ولو إجي الـ ACE على الجهاز التنفسي
+
+212
+00:21:01,140 --> 00:21:06,620
+مابتعملش حاجة ولو راح الـ corona على الجهاز العصبي
+
+213
+00:21:06,620 --> 00:21:12,320
+مابتعملش حاجة هذا لازم يروح عن طريق الأنف يبقى أنا
+
+214
+00:21:12,320 --> 00:21:17,620
+أندي main receptors مستقبلات كثيرة لبعض الفيروسات
+
+215
+00:21:17,620 --> 00:21:22,840
+خاصة بيروس الـ poliovirus شلل الأطفال بيروسات
+
+216
+00:21:22,840 --> 00:21:26,740
+مشلل الأطفال اللي هي تشتغل على الـ motor neurons
+
+217
+00:21:26,740 --> 00:21:33,020
+على الجهاز العصبي على الجهاز العصبي طيب الفيروس
+
+218
+00:21:33,020 --> 00:21:39,300
+مجرد ما يدخل بيكون هباء فبيجي هو بيعمل fusion للـ
+
+219
+00:21:39,300 --> 00:21:44,850
+virus envelope الفرصة envelope هذا بيعمل contact مع
+
+220
+00:21:44,850 --> 00:21:48,930
+الـ human membrane بتاع الإنسان أو الحيوان يعني هاي
+
+221
+00:21:48,930 --> 00:21:55,110
+الخلية الإنسانية هيك هو إيجى أول شي شبك بالشوكة
+
+222
+00:21:55,110 --> 00:22:03,670
+بتاعته هنا بدأ ياخد من هنا metabolites لوازم نمو
+
+223
+00:22:04,430 --> 00:22:08,830
+يبقى .. يبقى عمل fusion بين الـ end lob الخارجي
+
+224
+00:22:08,830 --> 00:22:15,970
+بتاعه وبين الخلية الحية للإنسان أو الحيوان مما أدى
+
+225
+00:22:15,970 --> 00:22:22,790
+إلى عمل فتحة معينة في الددار هذه الفتحة إيه صار
+
+226
+00:22:22,790 --> 00:22:29,510
+الفيروس اللي كان برا صار يهوة يبقى هذا عمل access
+
+227
+00:22:29,510 --> 00:22:34,080
+access يعني مدخلمدخل الـ neurocapsid اللي هو الحبل
+
+228
+00:22:34,080 --> 00:22:41,820
+النووي في الداخل وبعدين صار عمل endocytosis أي
+
+229
+00:22:41,820 --> 00:22:46,740
+إنّه دفن حاله داخل الخلية خلاص ماعادش الوضع صار هيك
+
+230
+00:22:46,740 --> 00:22:54,280
+هذه الخلية هو هنا هو هنا عن طريق الـ proteolysis
+
+231
+00:22:54,280 --> 00:23:00,620
+أذابت غلاف الخلية هنا هو وجب هنا أذاب وفتح فتحة
+
+232
+00:23:00,620 --> 00:23:05,160
+proteolysis وبعدين راح دخل صار inside the cell
+
+233
+00:23:05,160 --> 00:23:12,580
+صار inside the cell طيب الآن ببدأ يتكاتر
+
+234
+00:23:12,580 --> 00:23:17,100
+replication يعني تكاتر gets replicated in
+
+235
+00:23:17,100 --> 00:23:23,990
+different ways بطرق مختلفة والـ RNA فريد الـ RNA
+
+236
+00:23:23,990 --> 00:23:30,510
+unique فريد لأن الـ RNA الـ genetic map بتاعه في
+
+237
+00:23:30,510 --> 00:23:34,470
+الخياطة الجينية ممكن يطلع منها virus أو فيروسات
+
+238
+00:23:34,470 --> 00:23:39,130
+جديدة RNA أو فيروسات جديدة DNA يعني الـ RNA ممكن
+
+239
+00:23:39,130 --> 00:23:44,950
+يتحول لـ DNA أو يظل RNA ويطلع ملايين فيروسات RNA أو
+
+240
+00:23:44,950 --> 00:23:49,370
+يتحول لـ DNA ويطلع ملايين فيروسات جديدة من DNA أما
+
+241
+00:23:49,370 --> 00:23:55,590
+الـ DNA لحاله بيظل DNA يعني فيروس الـ DNA بيظل DNA
+
+242
+00:23:55,590 --> 00:24:02,010
+لكن فيروس الـ RNA ممكن يتحول لـ DNA أو يظل RNA لذا
+
+243
+00:24:02,010 --> 00:24:06,850
+الفيروسات الـ DNA أما هي DNA من أبو أبو أبو أبوها أو
+
+244
+00:24:06,850 --> 00:24:12,750
+هي محورة من RNA DNA محورة من RNA فأنا بقول لك إن
+
+245
+00:24:12,750 --> 00:24:18,800
+هدول الـ DNA RNA unique unique لأنه ممكن يتكاتروا
+
+246
+00:24:18,800 --> 00:24:26,420
+ويتطلعوا اما DNA أو RNA طيب ما هي الصورة الـ
+
+247
+00:24:26,420 --> 00:24:31,960
+إكلينيكية الصورة الإكلينيكية للـ viral infection
+
+248
+00:24:31,960 --> 00:24:37,580
+العدوى الفيروسية هو طبعا كل فيروس له حاجاته للعراض
+
+249
+00:24:37,580 --> 00:24:42,050
+اللي هو بيعملها لكن في أحيان تكون أعراض مشتركة تحصى
+
+250
+00:24:42,050 --> 00:24:46,470
+في البداية الأراضي المشتركة اكود فبرايه الناس
+
+251
+00:24:46,470 --> 00:24:52,650
+فبرايه يعني حرارة يبقى حرارة حادة ممكن تصل الى 104
+
+252
+00:24:52,650 --> 00:24:58,970
+فهرنهايت يعني الـ 104 فهرنهايت ممكن تصل الى 40 درجة
+
+253
+00:24:58,970 --> 00:25:04,810
+مئوية مثلا ومعها chills chills يعني رجفة برجف
+
+254
+00:25:04,810 --> 00:25:10,880
+برجف ومعها headache سواء مهما يلجأ ألم العضلات
+
+255
+00:25:10,880 --> 00:25:17,280
+ومهما ليس يعني ارتخاء ودروحة من يومين إلى أسبوع في
+
+256
+00:25:17,280 --> 00:25:23,460
+المتوسط بخمس أيام يبدأ يسخن عندما يبدأ يسخن هذا
+
+257
+00:25:23,460 --> 00:25:30,120
+الشخص قبل استعمال انفروانزا ولا كورونا ولا فيروس
+
+258
+00:25:30,120 --> 00:25:35,920
+البرد في الأول يسخنو بعدين ببدأ ألام ورجفاء و
+
+259
+00:25:35,920 --> 00:25:42,780
+دروخة ونعس مدة أربع إلى خمس أيام وبيقول لي إنه
+
+260
+00:25:42,780 --> 00:25:46,080
+حتى ممكن بعضهم يخش على الجسر وأنت تستنى للـ track
+
+261
+00:25:47,300 --> 00:25:53,100
+هو يعمل تقئ ويعمل إسهال وبعضهم يدخلوا على الـ
+
+262
+00:25:53,100 --> 00:25:59,060
+system على الجهاز التنفسي زي الكورونا مثلا يدخلوا
+
+263
+00:25:59,060 --> 00:26:01,680
+على الجهاز التنفسي وفي بعضهم يدخلوا على الجثر
+
+264
+00:26:01,680 --> 00:26:05,400
+الستينال وفي بعضهم يدخلوا على الـ nervous system بس
+
+265
+00:26:05,400 --> 00:26:08,990
+الجثر الستينال مثال لكن مش كلهم gut-front-sternal
+
+266
+00:26:08,990 --> 00:26:13,670
+في gut-front-sternal في respiratory اه بسبب الـ
+
+267
+00:26:13,670 --> 00:26:22,210
+system وفي nervous system وفي genital system يعني
+
+268
+00:26:22,210 --> 00:26:28,680
+التناسلي gs gs يعني genital system وفي بروع الـ I
+
+269
+00:26:28,680 --> 00:26:33,080
+والـ I احنا عشان احنا دراستنا في العين نهتم شوية
+
+270
+00:26:33,080 --> 00:26:36,500
+بنزوّل فيها حبتين تعمل conjunctivitis يعني التهاب
+
+271
+00:26:36,500 --> 00:26:41,520
+المتحمة تعمل uveitis التهاب القزحية و التهاب الجسم
+
+272
+00:26:41,520 --> 00:26:46,890
+الهدوي مثلا اه ممكن تعمل retinitis بعض الفيروسات
+
+273
+00:26:46,890 --> 00:26:51,270
+تعمل bilateral retinitis يعني التهاب في العين تاني
+
+274
+00:26:51,270 --> 00:26:55,310
+اللي هو الشبكية اه و تعمل loss of central vision
+
+275
+00:26:55,310 --> 00:26:59,930
+لما الماكورة تنضرب بصير loss of central vision لأن
+
+276
+00:26:59,930 --> 00:27:03,290
+الماكورة بتعمل central vision خلال ثلاث أسابيع من
+
+277
+00:27:03,290 --> 00:27:07,870
+البداية كمان في العين ممكن تصير macular
+
+278
+00:27:07,870 --> 00:27:14,050
+exfoliation رشح يعني على الماكولا وممكن نسيب كمان
+
+279
+00:27:14,050 --> 00:27:19,150
+في الشبكية hemorrhage يعني نظيف vasocolitis يعني
+
+280
+00:27:19,150 --> 00:27:23,650
+التهاب اللي هو الشرايين و vascular occlusion 
+
+281
+00:27:23,650 --> 00:27:29,490
+وانسداد الشرايين زي انسداد the central retinal artery
+
+282
+00:27:29,490 --> 00:27:33,920
+و the central retinal vein هذه شيء خطيروهذا بيكشفوه
+
+283
+00:27:33,920 --> 00:27:36,720
+اللي هو الانجيوجرافي fluorescein angiography يعني
+
+284
+00:27:36,720 --> 00:27:40,360
+بيعطوه فجنة الفلورسين في الوريد و بيصوروا عينه
+
+285
+00:27:40,360 --> 00:27:44,700
+بالكاميرا اسمها the fundus camera بيصوروها و بيبين
+
+286
+00:27:44,700 --> 00:27:49,420
+وين التسكيط لما يكون فيه vascular occlusion يعني
+
+287
+00:27:49,420 --> 00:27:54,960
+سواء انسداد شرياني او انسداد وريدي the fluorescein
+
+288
+00:27:54,960 --> 00:28:02,340
+angiography اللي بيسموه FFF FFA fluorescein angiography
+
+289
+00:28:02,340 --> 00:28:10,000
+الأن جيوجرافي هذه اللي هي بالكاميرا بتبين ممكن اللي
+
+290
+00:28:10,000 --> 00:28:14,640
+يعني ان بعض أعراض العين انه سيها resolve أو
+
+291
+00:28:14,640 --> 00:28:19,960
+resolution تنتهي وبعضها ممكن يقضي الى العمى عمى في
+
+292
+00:28:19,960 --> 00:28:24,290
+الحالات الخطيرة serious cases ممكن أنه يصير loss
+
+293
+00:28:24,290 --> 00:28:29,270
+of central vision ممكن يفقد النظر بالماكولا في
+
+294
+00:28:29,270 --> 00:28:31,130
+عينين وعينين وعينين وعينين وعينين وعينين وعينين
+
+295
+00:28:31,130 --> 00:28:31,950
+وعينين وعينين وعينين وعينين وعينين وعينين وعينين
+
+296
+00:28:31,950 --> 00:28:32,750
+وعينين وعينين وعينين وعينين وعينين وعينين وعينين
+
+297
+00:28:32,750 --> 00:28:39,830
+وعينين وعينين وعينين وعينين وعينين وعينين وعينين
+
+298
+00:28:39,830 --> 00:28:44,540
+وعينينهو ممكن يصير ischemic maculopathy الماكولا
+
+299
+00:28:44,540 --> 00:28:48,500
+مايصلهاش دم كافي شوفوا the virus ايش عمل في العين
+
+300
+00:28:48,500 --> 00:28:53,120
+بهدل العين و يعني و خلها عاملة اه بقول انه ممكن
+
+301
+00:28:53,120 --> 00:28:58,740
+يكونيعني كمان غير العين انه serious sequelae يعني
+
+302
+00:28:58,740 --> 00:29:06,100
+في توابع خطيرة انه تسيب الكبد Hepatitis وتسيب المخ
+
+303
+00:29:06,100 --> 00:29:10,800
+Encephalitis وتسيب اللي هو البطن visceral
+
+304
+00:29:10,800 --> 00:29:13,770
+hemorrhage كل هذا الفيروس عملوه يعني احنا الله
+
+305
+00:29:13,770 --> 00:29:17,430
+معافينا الحمد لله عشنا هذا الزمن وماصارش معناه من
+
+306
+00:29:17,430 --> 00:29:20,630
+هالاشياء هذه ربما التطعيم اللي أخدناه و احنا صغار
+
+307
+00:29:20,630 --> 00:29:25,430
+كان عامل مساعد يعني بإذن الله عامل مساعد الان يعني
+
+308
+00:29:25,430 --> 00:29:29,970
+أي ولاد من ولاد بيعطيه امه دفتر يعني للتطعيم كل
+
+309
+00:29:29,970 --> 00:29:35,530
+شهرين تلاتة بتروح تعطيه تطعيم ضد الفيروسات حتى لما
+
+310
+00:29:35,530 --> 00:29:41,870
+يكبر ماصيرلوش مضاعفات هي مثلا صورة كيف the adenovirus
+
+311
+00:29:41,870 --> 00:29:46,930
+واحد منهم عمل keratitis التهاب في القرنية وعمل
+
+312
+00:29:46,930 --> 00:29:52,290
+اللي هو نوع من the opacities، opacities هنا هيها يعني
+
+313
+00:29:52,290 --> 00:29:56,730
+هيبين لحظة هذا فرصيا حطينا وكيف انه the mucus من
+
+314
+00:29:56,730 --> 00:30:03,130
+brain متبهدل و انه بعد هيك لمطيب بيعمل opacities طيب
+
+315
+00:30:03,130 --> 00:30:06,310
+مقول
+
+316
+00:30:06,310 --> 00:30:11,210
+the herpes viruses the herpes viruses مجموعة أو
+
+317
+00:30:11,210 --> 00:30:16,170
+عائلة اسمها herpes viruses يبقى هي family عائلة
+
+318
+00:30:16,170 --> 00:30:22,820
+اسمها herpes فيها كتير من الأعضاء ضمنهم the
+
+319
+00:30:22,820 --> 00:30:29,040
+herpes simplex virus HSV herpes simplex virus وهذا
+
+320
+00:30:29,040 --> 00:30:33,920
+من أكثر الفيروسات اللي بصيب القرنية وممكن يعمل
+
+321
+00:30:33,920 --> 00:30:39,020
+فيها opacities يعني أتمنا اه بقول ان the family
+
+322
+00:30:39,020 --> 00:30:43,100
+members هي دي هنعدد منها خمسة وبعدين نتناولها واحد
+
+323
+00:30:43,100 --> 00:30:47,460
+واحد في واحد اسمه cytomegalic virus أي الفيروس
+
+324
+00:30:47,460 --> 00:30:54,140
+الضخم cytomegalic خلية وmegalic يعني كبير أو ضخم
+
+325
+00:30:54,140 --> 00:31:03,800
+في Epstein Barr virus EBV Epstein Barr virus في
+
+326
+00:31:03,800 --> 00:31:12,970
+human herpes virus ثمانية اه ويله اسم ناس بيسموه
+
+327
+00:31:12,970 --> 00:31:21,810
+keratic sarcoma herpes virus keratic يعني
+
+328
+00:31:21,810 --> 00:31:28,530
+قرنية اه sarcoma ورم من أحد الأورام يسمى Sarcoma
+
+329
+00:31:28,530 --> 00:31:37,010
+Herpes A Virus بس HP8 يمكن أسهل في Herpes Virus B
+
+330
+00:31:37,010 --> 00:31:41,770
+A فيه بيسموه Ocular Infections Cause Ocular
+
+331
+00:31:41,770 --> 00:31:44,870
+Infections يعني عدوى في العين وHerpes Simplex
+
+332
+00:31:44,870 --> 00:31:49,150
+Virus A اللي هو الشهير اللي احنا قلنا عنه يصيب
+
+333
+00:31:49,150 --> 00:31:52,930
+العين ويدمر القرنية
+
+334
+00:31:56,110 --> 00:32:02,450
+طيب في قواسم مشتركة للعائلة هذه أو قواسم مشتركة
+
+335
+00:32:02,450 --> 00:32:08,850
+القواسم المشتركة الأولى لعائلة the virus is انها كلها
+
+336
+00:32:08,850 --> 00:32:16,570
+double strand DNA يعني حبلين DNA double مش single
+
+337
+00:32:19,840 --> 00:32:28,780
+و كلها اه في amorphous area between the capsid and
+
+338
+00:32:28,780 --> 00:32:32,860
+envelope احنا عرفنا the capsid قبل شوية اللي كان
+
+339
+00:32:32,860 --> 00:32:40,480
+وردي و عرفنا envelope في منطقة يعني معينة فاصلة
+
+340
+00:32:40,480 --> 00:32:45,820
+بين الاثنين يعني لو رجعنا احنا للصورة هذه هنا هيها
+
+341
+00:32:45,820 --> 00:32:59,180
+بين اللي هو the envelope هذا و بين اللي هو the
+
+342
+00:32:59,180 --> 00:33:06,780
+segment هذا في منطقة عازلة في منطقة عازلة منطقة
+
+343
+00:33:06,780 --> 00:33:09,840
+عازلة معينة بين الاثنين
+
+344
+00:33:12,820 --> 00:33:19,880
+طيب الشيء الثالث the segment هذا فيه عدة بروتينات
+
+345
+00:33:19,880 --> 00:33:26,740
+اه وهذه البروتينات لو دخلت في خلية حية توقف نمو
+
+346
+00:33:26,740 --> 00:33:32,820
+البروتين أو تصنيع البروتين نفسي بال ribosomes داخل
+
+347
+00:33:32,820 --> 00:33:38,380
+الخلية الحية مثل الإنسان يعني هذه الخلية لما تخش
+
+348
+00:33:38,380 --> 00:33:43,640
+هنا تستطيع ان توقف من the ribosomes اللي بتكون هنا
+
+349
+00:33:43,640 --> 00:33:49,900
+ribosomes توقف تصنيع البروتينات الانسانية في
+
+350
+00:33:49,900 --> 00:33:56,580
+الخلية طيب احنا هنتوقف عند the cytomegalic virus على
+
+351
+00:33:56,580 --> 00:34:01,560
+امل ان شاء الله انه نبدأ في المحاضرة التاسعة و
+
+352
+00:34:01,560 --> 00:34:06,420
+العشرين يعني احنا ان شاء الله ماشيين بني تعالى يعني
+
+353
+00:34:06,420 --> 00:34:11,120
+ماشي كويس بحيث انه نخلص في موعد المناسب 
diff --git a/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/fo1SxaSczuc_postprocess.srt b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/fo1SxaSczuc_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..6f51377bc89933aae00335d51b03e7040536eb93
--- /dev/null
+++ b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/fo1SxaSczuc_postprocess.srt
@@ -0,0 +1,796 @@
+1
+00:00:00,660 --> 00:00:05,000
+عوض بالله من الشيطان الرجيم بسم الله الرحمن الرحيم
+
+2
+00:00:05,000 --> 00:00:09,260
+الحمد لله وكفا و أصلي و أسلم على النبي المصطفى
+
+3
+00:00:09,260 --> 00:00:13,080
+طالبات العزيزات في قسم البصريات الطبية المستوى
+
+4
+00:00:13,080 --> 00:00:17,580
+الثالث احنا وصلنا الى المحاضرة السابعة عشرة و كنا
+
+5
+00:00:17,580 --> 00:00:23,760
+قد ارسلنا لكم عبر الواتس اب ان الامتحان النصفي هو
+
+6
+00:00:23,760 --> 00:00:29,550
+عند اخر محاضرة الخمس عشر coronavirus عند اخرهاأما
+
+7
+00:00:29,550 --> 00:00:35,410
+المحاضرات التي تتلو هذا فهي غير داخلة إلا في
+
+8
+00:00:35,410 --> 00:00:40,790
+الامتحان النهائي فاطمأنوا أن أريد منكم أن تراجعوا
+
+9
+00:00:40,790 --> 00:00:47,090
+15 محاضرة تماما و تستعدوا لامتحان بها على طريقة
+
+10
+00:00:47,090 --> 00:00:53,180
+true and false وطريقة الخيارات المتعددةأما الآن
+
+11
+00:00:53,180 --> 00:00:59,980
+فسوف نحاول جاهدين ان شاء الله ان نختم ال .. اللي
+
+12
+00:00:59,980 --> 00:01:04,760
+هو يعني هذا الجزء من المساق اللي هو الجزء العام
+
+13
+00:01:04,760 --> 00:01:08,850
+يعني ال general microbiologyوبعد هيك ان شاء الله
+
+14
+00:01:08,850 --> 00:01:14,530
+نستعد ان ندخل في microbiology of the eye يعني اللي
+
+15
+00:01:14,530 --> 00:01:18,030
+يتعلق الميكروبات اللي تتسيب العين نفسها فاليوم بس
+
+16
+00:01:18,030 --> 00:01:22,990
+احنا سنختم اللي هو ال proto دوة الثالث gardia
+
+17
+00:01:22,990 --> 00:01:28,110
+lamblia هذا من أكثر اللي هو الكائنات الحية اللتي
+
+18
+00:01:28,110 --> 00:01:33,010
+تصيب الأطفال وتمنع نموهم وتمنع نموهم هو
+
+19
+00:01:33,010 --> 00:01:39,230
+flagellated يعني له أقدام يتحرك بهاويعني بيعيش في
+
+20
+00:01:39,230 --> 00:01:42,550
+الأمعاء الدقيقة في small intestine either
+
+21
+00:01:42,550 --> 00:01:47,890
+frequently most frequently يعني دائما يعني يوجد ان
+
+22
+00:01:47,890 --> 00:01:53,550
+هو في الأمعاء الدقيقة مش عائل الا الإنسان مالوش
+
+23
+00:01:53,550 --> 00:01:57,610
+عائل وسيطة زي باقي البروتوجوه من الغنم والفئران
+
+24
+00:01:57,610 --> 00:02:04,000
+والقطط والطيور بس هو الإنسانيعني ممكن انسان يكون
+
+25
+00:02:04,000 --> 00:02:09,580
+حالة مرضية او يكون carrier يعني حامل الجردية ولا
+
+26
+00:02:09,580 --> 00:02:15,320
+تبدو عليه كيف يتم العدوى؟ يتم العدوى بالذي هو
+
+27
+00:02:15,320 --> 00:02:19,840
+تناول الطعام و شراب الملوثين بميكروب الجردية
+
+28
+00:02:19,840 --> 00:02:23,420
+اللاملية water and food وهو هذا معروف انه water
+
+29
+00:02:23,420 --> 00:02:29,050
+barn يعني هو بيجي مع الطعام بيجي مع الطعامهذه
+
+30
+00:02:29,050 --> 00:02:32,490
+الطريقة غير مباشرة عن طريق الذباب انه طعام وشرب
+
+31
+00:02:32,490 --> 00:02:36,070
+نباتين وفي طريقة إدارة contact اللي هو hand to
+
+32
+00:02:36,070 --> 00:02:40,690
+hand يعني واحد يكون يعني حامل او مريض للجذية
+
+33
+00:02:40,690 --> 00:02:44,690
+وبيسلم على الناس بعد ما يدّي البراز من غير مغسل
+
+34
+00:02:44,690 --> 00:02:48,690
+إيدي جيدا بالماء والصابون فهذه الطريقة اسمها
+
+35
+00:02:48,690 --> 00:02:52,450
+direct الطريقة الأولى اللي هي عن طريق الذباب طريقة
+
+36
+00:02:52,450 --> 00:02:56,100
+غير مباشرة in directin direct هذه طريقة العدوى
+
+37
+00:02:56,100 --> 00:03:02,380
+mode of infection يعني طريقة العدوى طيب هذا إنسان
+
+38
+00:03:02,380 --> 00:03:08,560
+فى براده طلقة gardia وال gardia هذه بتكون cyst
+
+39
+00:03:08,560 --> 00:03:13,240
+يعني بتكون حوصلة هذه بيحملها دباب إلى طعام و شراب
+
+40
+00:03:13,240 --> 00:03:18,550
+الناسأه بحيث لو يعني أكلوه ممكن انه ينعلوه يمكن
+
+41
+00:03:18,550 --> 00:03:23,830
+انه ينعلوه هاي الشكل بتاع الجرذيا اه هاد ال cyst و
+
+42
+00:03:23,830 --> 00:03:31,290
+هاد ال active اللي هو stage ال active stage طيب
+
+43
+00:03:31,290 --> 00:03:38,990
+الشيء العجيب انه هذا الكائن اللي حي الجرذيا انه لا
+
+44
+00:03:38,990 --> 00:03:43,460
+يقتل بال chlorine ال chlorine يعنيالكلور بيحطوهم
+
+45
+00:03:43,460 --> 00:03:50,720
+لل water supply عساس انه يعني انه يقطوا الميكروبات
+
+46
+00:03:50,720 --> 00:03:54,620
+اللي فيه ماء القبار او ماء الأنهار فوجدوا ان
+
+47
+00:03:54,620 --> 00:04:00,080
+الكلور بتعيش فيه ال cyst can survive يعني تعيش فيه
+
+48
+00:04:00,080 --> 00:04:05,580
+رغم الكلور وهذا يؤدي إلى شيوعه ك water born
+
+49
+00:04:05,580 --> 00:04:09,890
+diseaseيعني كتير في الميه اللى احنا مشربها في هذا
+
+50
+00:04:09,890 --> 00:04:14,790
+الميكروب و احنا مش حاسينه و لأنه الكلور بأثرش فيه
+
+51
+00:04:14,790 --> 00:04:20,230
+طيب المصاب بالمرض اسمه gardiasis يعني هي اسمها
+
+52
+00:04:20,230 --> 00:04:25,450
+gardia الميكروب اسمه gardia المرض اسمه gardiasis
+
+53
+00:04:25,450 --> 00:04:28,350
+ال gardiasis طبعا هذا بيصير في ال small intestine
+
+54
+00:04:28,350 --> 00:04:31,850
+الأمعاي الدقيقة الأمعاي الدقيقة ايش الواحد بيحس
+
+55
+00:04:31,850 --> 00:04:35,690
+اول اشي بيحس فيه cramping cramping تقلصات معاوية
+
+56
+00:04:36,430 --> 00:04:42,050
+وبحث بلوتنج انتفاخ غازات انتفاخ تلاتة بحث فتيج في
+
+57
+00:04:42,050 --> 00:04:48,170
+شمعة مجهود المجهود يعني الفتيج ليش جاي لأنه في
+
+58
+00:04:48,170 --> 00:04:54,530
+poor food absorption ليش poor food absorption يعني
+
+59
+00:04:54,530 --> 00:04:59,890
+في ضعف في انتصار الطعام لأن الأمعاء الدقيقة لو
+
+60
+00:04:59,890 --> 00:05:04,050
+أخدنا قطاع فيها هذه الأمعاء الدقيقة مبطئ بغشاء
+
+61
+00:05:04,050 --> 00:05:10,200
+مخاطئ له خملاتالو بالله يعني ايش بالله هذه الخملات
+
+62
+00:05:10,200 --> 00:05:15,780
+هذه الخملات هي الانبيب
+
+63
+00:05:15,780 --> 00:05:20,860
+الدقيقة الميكروسكوبية اللي يمتص منها الطعام المذاب
+
+64
+00:05:20,860 --> 00:05:25,540
+الطعام المذاب اسمه كائل يبقى الطعام بعد ما يصل
+
+65
+00:05:25,540 --> 00:05:28,840
+لأمعاد دقيقة بيصل دائب بعد هضمه في المعدة أو في
+
+66
+00:05:28,840 --> 00:05:33,420
+الاتناشر و بيصل دائب ال microbe هذا جالس هنا
+
+67
+00:05:33,990 --> 00:05:37,330
+الميكروب هاد جاعد هنا على رأس الفلاي على رأس
+
+68
+00:05:37,330 --> 00:05:43,770
+الأنبوب الآن لما ييجي الطعام عشان يمطص من الخملات
+
+69
+00:05:43,770 --> 00:05:49,270
+بيلاجي الجارديا جاعداله يعني الطعام هو ماشي هيك و
+
+70
+00:05:49,270 --> 00:05:55,450
+بده يخش في الأنابيب هذه عشان يروح الدم بيلاجي
+
+71
+00:05:55,450 --> 00:06:00,270
+الجارديا جاعداله مسكرة الأنبوب و بيمطص الطعام هذا
+
+72
+00:06:00,270 --> 00:06:07,130
+فبصير الطعامالقليل منه اللي بيخش من الخملات ففي
+
+73
+00:06:07,130 --> 00:06:12,870
+poor food absorption وبالتالي مهما يأكل بيبينش فيه
+
+74
+00:06:12,870 --> 00:06:18,090
+وبالتالي في fatigue يعني لو الولد هذا تقولله اشتري
+
+75
+00:06:18,090 --> 00:06:24,850
+كيلو سكر من المحل بيجي يلهت طب ليش ولد عمره عشر
+
+76
+00:06:24,850 --> 00:06:28,370
+سنين بيلهت من كيلو سكر لأنه مافيش عنده طاقة الطعام
+
+77
+00:06:28,370 --> 00:06:32,310
+اللي بيأكله بيبينش عليهوبالتالي في weight loss
+
+78
+00:06:32,310 --> 00:06:37,830
+يعني إيش الفيضة ياخد البروتين وياخد ال
+
+79
+00:06:37,830 --> 00:06:41,290
+carbohydrate في طعامه وياخد دهون وياخد أملح وياخد
+
+80
+00:06:41,290 --> 00:06:46,530
+فيتامينه لكن في weight loss يعني عمال بينجص مش
+
+81
+00:06:46,530 --> 00:06:50,790
+بينزل بينجص مش بيزيل ف cramping, bloating,
+
+82
+00:06:50,930 --> 00:06:56,760
+fatigue, weight losschronic greasy diarrhea دياريا
+
+83
+00:06:56,760 --> 00:07:03,360
+يعني إسهال دهني يعني لو مسكن الإسهال البراز و احنا
+
+84
+00:07:03,360 --> 00:07:09,220
+نابسين جوانتيوحسيناه بيلاقيه بيزحلك يعني هو ذهني
+
+85
+00:07:09,220 --> 00:07:13,860
+ليش؟ لأن الطعام او الذهون والذيوت اللي في الطعام
+
+86
+00:07:13,860 --> 00:07:18,600
+لم تمتص وطلعك في البراز سودان مااستفدش منها
+
+87
+00:07:18,600 --> 00:07:21,460
+فالجريزي ضيارية وملاحظين الجريزي ضيارية احنا
+
+88
+00:07:21,460 --> 00:07:26,200
+مااتكلمناش عنها قبل هيك واحد بيعملها يعني الاسهال
+
+89
+00:07:26,200 --> 00:07:30,520
+الدهني المزمن مااتكلمناش عنه الا هنا اخدنا اسهال
+
+90
+00:07:30,520 --> 00:07:35,510
+دموي او اسهال غير دموي لكن اسهال دهني مااخدنهوشهذه
+
+91
+00:07:35,510 --> 00:07:42,630
+أعراض اللوغارديا لمبيا أو gardiasis طبعا لو أخدنا
+
+92
+00:07:42,630 --> 00:07:46,530
+في البوراز تحليل هنلاقي ان ال cyst موجودة في
+
+93
+00:07:46,530 --> 00:07:51,510
+الفيسز في البوراز ال cyst موجودة في الفيسز هذه
+
+94
+00:07:51,510 --> 00:07:56,090
+طبعا للتشخيص ولا علاج لو احنا لجينا ال cyst معناه
+
+95
+00:07:56,090 --> 00:08:01,690
+انه احنا هنعطيه في يعني علاجات معينةأه ومن هذه
+
+96
+00:08:01,690 --> 00:08:08,010
+الفلاجين وغير الفلاجين لتعالج هذه الميكروبات اخر
+
+97
+00:08:08,010 --> 00:08:12,990
+اشي في ال general microbiology ما هي الاحتياطات
+
+98
+00:08:12,990 --> 00:08:19,250
+اللازمة او اللازم اخدها عند ارسال العينة المخبرية
+
+99
+00:08:19,250 --> 00:08:24,850
+للمختبر يعني احنا لما بدنا نشخص مرض بدنا ناخد عينة
+
+100
+00:08:24,850 --> 00:08:29,600
+مخبرية وبالتالي العينة المخبرية هذه كيف تصل بسلامو
+
+101
+00:08:29,600 --> 00:08:36,020
+تنفحص و يتشخص ايش فيها و بترجع لصاحبها او للطبيب
+
+102
+00:08:36,020 --> 00:08:40,280
+اللي ارسلها عشان يكتب علاج هذا فيه تمني احتياطات
+
+103
+00:08:40,280 --> 00:08:44,220
+اساسية لازم ناخدها كويس و الا بيكون شغل المختبر
+
+104
+00:08:44,220 --> 00:08:52,620
+شغل خطأ اول شيء اخذ العين او العينات اثناء النشاط
+
+105
+00:08:52,620 --> 00:08:58,150
+المرضى المرض نشيط مانخدهاش بعد العلاجduring the
+
+106
+00:08:58,150 --> 00:09:02,650
+active stage ليش؟ لأن الorganism يكون موجود يعني
+
+107
+00:09:02,650 --> 00:09:11,330
+مثلا واحد مع لوز أو مع التهاب رئوي أو مع التهاب في
+
+108
+00:09:11,330 --> 00:09:16,670
+البول أو التهاب في الأمعاء أثناء الألم و أثناء
+
+109
+00:09:16,670 --> 00:09:21,430
+السخونة و أثناء الرسالة و أثناء الكحةوهي على أخرها
+
+110
+00:09:21,430 --> 00:09:25,770
+شديدة ناخد العينة باللهجة ال organism لكن لو
+
+111
+00:09:25,770 --> 00:09:29,350
+سبناها أسبوع أو أسبوعين خاصة بعد ما اتعالج و
+
+112
+00:09:29,350 --> 00:09:31,490
+ناخدها ما نلاقي شيء ما نلاقي شيء ال organism
+
+113
+00:09:31,490 --> 00:09:35,930
+عالفاضي يبقى تاخد العينة أثناء النشاط المرضي
+
+114
+00:09:35,930 --> 00:09:43,610
+الزائد يجب أن تاخد العينة قبل تناول أي علاج before
+
+115
+00:09:43,610 --> 00:09:48,370
+givingthe patient in the treatment خاصة المضادات
+
+116
+00:09:48,370 --> 00:09:52,170
+الحيوية يعني لو واحد معنا التهابات في أي مكان أو
+
+117
+00:09:52,170 --> 00:09:57,090
+عدوة في جسمه وعطينا كابسولة واحدة مضاد حيوي واخدنا
+
+118
+00:09:57,090 --> 00:10:01,150
+منه عينة بعد ساعات مش هنلاقي الميكروب الميكروب
+
+119
+00:10:01,150 --> 00:10:09,730
+بيختفي بطريقة علمية بيلاقوهش لذلك قبل ما ناخد يعني
+
+120
+00:10:09,730 --> 00:10:16,020
+عينة مخبرية عشان شخص بكتيرياسواء كتم البول أو
+
+121
+00:10:16,020 --> 00:10:24,520
+البراز أو الدم أو السائل المنوي أو القصبة الهوائية
+
+122
+00:10:24,520 --> 00:10:32,520
+كله لازم يكون قبل تناول أي علاج تلاتة وضع
+
+123
+00:10:32,520 --> 00:10:37,260
+ال specimens اللي هي العينات في sterile containers
+
+124
+00:10:37,260 --> 00:10:44,160
+sterile containers يعني في وعاء معقّموتم اغلاقه
+
+125
+00:10:44,160 --> 00:10:49,720
+جيدا حتى لا يحدث leak leak يعني نزب خارجي يعني انه
+
+126
+00:10:49,720 --> 00:10:55,620
+يصير تنجيت برا يعني عناق مش مسكر كويس ومال بصير
+
+127
+00:10:55,620 --> 00:11:02,000
+سيء leak او break او كثر طيب ليش احنا الحكمة انه
+
+128
+00:11:02,000 --> 00:11:06,900
+بنحط العينة دم او بول او براز او بلغم ليش بنحطه في
+
+129
+00:11:06,900 --> 00:11:11,720
+استرال كونتينة بنخاف انه احناان جيب اي container
+
+130
+00:11:11,720 --> 00:11:16,780
+اجزادها من الدار مثلا تكون ملوحة و حطينا فيها الدم
+
+131
+00:11:16,780 --> 00:11:22,600
+او البول او البراز و راح فحص المختبر لجي اللي هو
+
+132
+00:11:22,600 --> 00:11:28,920
+ال microbe الاول يعني مافي ال microbe الجديد لأ او
+
+133
+00:11:28,920 --> 00:11:33,040
+لجي التنينفاحنا الأحسن قبل ما ناخد عينة بنروح على
+
+134
+00:11:33,040 --> 00:11:37,380
+الصيدرية أو على المختبر بنشتري اللي هو انبوب
+
+135
+00:11:37,380 --> 00:11:43,500
+اختبار مثلا مغلق بيكون مغلق من مختبره معقم جوا او
+
+136
+00:11:43,500 --> 00:11:49,350
+كاسة للبراز او للبلغم بتكون سكره معقمةو بيحط
+
+137
+00:11:49,350 --> 00:11:54,010
+المادة فيها و بنسكرها كويس كويس و بنبعتها الى
+
+138
+00:11:54,010 --> 00:11:59,110
+المقنبر عشان هو يفصل لكن لو خدنا اي اجزازة او اي
+
+139
+00:11:59,110 --> 00:12:02,590
+طبق من الدار و حطينا فيه البراز او ال bowl و
+
+140
+00:12:02,590 --> 00:12:07,750
+بروحنا ممكن يكون هو ملوت من الاساس رابعا عدم
+
+141
+00:12:07,750 --> 00:12:14,360
+التأخير مافيش delayany delay أخدنا العينة نرسلها
+
+142
+00:12:14,360 --> 00:12:18,160
+فورا since directly to lab without any delay بدون
+
+143
+00:12:18,160 --> 00:12:22,540
+أي تأثير خاصة في الجو الحاريعني لو أخدنا احنا مثلا
+
+144
+00:12:22,540 --> 00:12:25,960
+جوجل برا الذنب و خلانا ساعتين تلاتة خاصة في الجو
+
+145
+00:12:25,960 --> 00:12:30,820
+الحرم البكتيريا بتموت بنلاقي هش بروح بحلل المختبر
+
+146
+00:12:30,820 --> 00:12:35,900
+بلاقي false results يعني نتائج زائفة مش حقيقية
+
+147
+00:12:35,900 --> 00:12:40,780
+فعدم التأخير ناخد من الطفل او اي مريض ناخد منه
+
+148
+00:12:40,780 --> 00:12:46,800
+عينا و فورا خلال نص ساعة تكون في المختبر شيء خامس
+
+149
+00:12:46,800 --> 00:12:55,750
+انه احناالعينة لازم تكون مصاحبة ب full و accurate
+
+150
+00:12:55,750 --> 00:12:58,630
+information ايش يعني full و accurate information
+
+151
+00:12:58,630 --> 00:13:02,550
+يعني العينة هذه لو سبناها احنا من غير ما نحط عليها
+
+152
+00:13:02,550 --> 00:13:09,770
+الاسم و نحط عليها التاريخ و نحط عليها العمر و نحط
+
+153
+00:13:09,770 --> 00:13:14,290
+عليها ال clinical history من وين موجودة او ليش
+
+154
+00:13:14,290 --> 00:13:19,980
+موجودة و عنوان العين و رقم جوالهواللي هو نوع
+
+155
+00:13:19,980 --> 00:13:23,620
+العينة من البلغة من الدم من البراز من أي مكان في
+
+156
+00:13:23,620 --> 00:13:27,720
+الجسم بتضييع يبقى احنا العينة لازم يصاحبها
+
+157
+00:13:27,720 --> 00:13:32,540
+information يعني معلومات كاملة عن العينة وعن
+
+158
+00:13:32,540 --> 00:13:37,900
+صاحبها وعن عنوانه وعن نوع العينة وليش أخدناها عشان
+
+159
+00:13:37,900 --> 00:13:44,560
+اللي بيحلل يفهموهو بيعمل ال analysis خصية مختبر
+
+160
+00:13:44,560 --> 00:13:49,880
+يفهم هو ايش بيحلل بالظبط ولمين بيحلل ولمين يبعتها
+
+161
+00:13:49,880 --> 00:13:54,380
+على عنوان ويراجع سواء عنوانه في المستشفى او عنوانه
+
+162
+00:13:54,380 --> 00:13:59,760
+في يد الطبيب او عنوانه في البيت ثلاثة لازم تكون
+
+163
+00:13:59,760 --> 00:14:05,160
+عينة sufficient size to meet all necessary results
+
+164
+00:14:05,160 --> 00:14:12,670
+يعني احنا مثلابنحلل دم ناخد ملء النبوب مثلا خمسة
+
+165
+00:14:12,670 --> 00:14:17,090
+CC ماناخدش واحد CC ليش؟ لأنه ممكن أحيان يكون مطلوب
+
+166
+00:14:17,090 --> 00:14:25,350
+عدة يعني أنواع من التحليل يعني تحليل ل CBC حد دم
+
+167
+00:14:25,350 --> 00:14:33,210
+كامل تحليل ل مثلا بكتيريا تحليل لهرمونات تحليل
+
+168
+00:14:33,210 --> 00:14:38,950
+لإنزيمات تحليل يعني فاحناناخد عينة كاملة تكون
+
+169
+00:14:38,950 --> 00:14:45,790
+كبيرة مصفشا حتى لو في البراز لما بناخد ناخد من
+
+170
+00:14:45,790 --> 00:14:53,230
+النص ومن الطرف ومن فوق ومن تحت ونجمحها عساس انه
+
+171
+00:14:53,230 --> 00:15:03,170
+ايش انه تكون شاملة ومكافئة الفحص كله الشيء السابع
+
+172
+00:15:04,450 --> 00:15:09,890
+بتكون ال specimen representative تمثل تمثيل حقيقية
+
+173
+00:15:09,890 --> 00:15:15,750
+للمرض يعني مثلا واحد قولله عنده ثغر أوي كح كح كح
+
+174
+00:15:15,750 --> 00:15:22,520
+طلق البلغةأيش فيه دم؟ ايش فيه؟ فراح له تف تف عمل
+
+175
+00:15:22,520 --> 00:15:27,420
+لعاب هل هذا يمثل الحقيقة؟ لأ لا يمثل الحقيقة بيجي
+
+176
+00:15:27,420 --> 00:15:31,280
+اللي بحالي بيجي لعاب كلام فاضي يبقى احنا بنا مثلا
+
+177
+00:15:31,280 --> 00:15:35,520
+dispute and blame true مش saliva مش اللي هو اللعاب
+
+178
+00:15:35,520 --> 00:15:40,160
+فيه تحرير ال TB وامراض اخرى من اتهابات الجهاد
+
+179
+00:15:40,160 --> 00:15:44,300
+التنفسيمثلا احنا بنحلل السائل المنوي السائل المنوي
+
+180
+00:15:44,300 --> 00:15:49,100
+معروف يعني يؤخذ يعني بطريقة معينة بعد القذف مايديش
+
+181
+00:15:49,100 --> 00:15:53,580
+يعطيني urine يعطيني bowl ويقولي حلله عشان ال urine
+
+182
+00:15:53,580 --> 00:15:58,270
+هيطلع aspermia يعني مافيش فيه منوياتوبالتالي احنا
+
+183
+00:15:58,270 --> 00:16:03,190
+يعني بدنا نضحكش لحالنا يعني احنا بدنا ان العينة
+
+184
+00:16:03,190 --> 00:16:07,650
+تكون representative تمثل تمثيل حقيقية المرض وليس
+
+185
+00:16:07,650 --> 00:16:12,090
+فقط انه ناخد اي عينة مانفعش يعني الصليد مثلا لازم
+
+186
+00:16:12,090 --> 00:16:16,910
+بقط الدمل و ناخد صليد مش انه نقصه و ناخد نتفة
+
+187
+00:16:16,910 --> 00:16:22,610
+سائلة هيك لأ لازم ناخد الصليد الحقيقيالاخر شي ان
+
+188
+00:16:22,610 --> 00:16:27,550
+يكون ال specimen عليها label وال label هذا ملصق
+
+189
+00:16:27,550 --> 00:16:34,470
+تماما يعني مثلا مثلا لاصق او blaster ومكتوب عليه
+
+190
+00:16:34,470 --> 00:16:39,350
+كل المعلومات مش اول ما يشيله الممرض يودع المختبر
+
+191
+00:16:39,350 --> 00:16:44,870
+يسحل ولمّا يصل المختبر يكون مالوش صاحب ولا عليه
+
+192
+00:16:44,870 --> 00:16:50,330
+تاريخ ولا عليه اسمولا عادى تمثيل مانفعش هذا السؤال
+
+193
+00:16:50,330 --> 00:16:54,870
+ان الله يحب احدكم اذا عامل عاملا ان يفقنا وبالتالي
+
+194
+00:16:54,870 --> 00:16:58,850
+هيك احنا بنكون يا بناتي خلصنا general microbiology
+
+195
+00:16:58,850 --> 00:17:02,450
+والمرة الجاية ان شاء الله بنكون في microbiology of
+
+196
+00:17:02,450 --> 00:17:05,510
+the eye اسأل الله عز وجل ان شاء الله نحضر الثامن
+
+197
+00:17:05,510 --> 00:17:08,290
+عشرة وانتم في احسن حال واحد اقبال والسلام عليكم
+
+198
+00:17:08,290 --> 00:17:09,850
+ورحمة الله وبركاته
+
+199
+00:17:17,390 --> 00:17:22,290
+هو هو هو
+
diff --git a/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/qoFbPnY6GRo_postprocess.srt b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/qoFbPnY6GRo_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..d8cb765461a3c9ffcdbcbab763fdcb047f8c6a9d
--- /dev/null
+++ b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/qoFbPnY6GRo_postprocess.srt
@@ -0,0 +1,1144 @@
+1
+00:00:01,280 --> 00:00:08,480
+بسم الله الرحمن الرحيم الحمد لله رب العالمين واصلي
+
+2
+00:00:08,480 --> 00:00:13,280
+واسلم على النبي الأمين محمد وعلى آله وأصحابه
+
+3
+00:00:13,280 --> 00:00:17,560
+والسابعين مناكي في خصم المصادر الطبية المستوى
+
+4
+00:00:17,560 --> 00:00:23,140
+الثالث اتخدم اليكم في المحاضرة الثالثة عشر من هذا
+
+5
+00:00:23,140 --> 00:00:30,140
+المسافر لمحاضرة جديدة وهي السنوالالبكتيريا التي
+
+6
+00:00:30,140 --> 00:00:35,600
+تصيب الأمعاء Enteritis تعني التهاب الأمعاء الدقيق
+
+7
+00:00:35,600 --> 00:00:41,440
+Enteritis-causing bacteria أي البكتيريا التي تسبب
+
+8
+00:00:41,440 --> 00:00:47,960
+التهابات أو العدوى داخل الأمعاء الدقيق هنا سنذكر
+
+9
+00:00:47,960 --> 00:00:53,220
+العديد من الأنواع ونحاول أن نفرق بينها هي لها
+
+10
+00:00:53,220 --> 00:00:58,830
+خصائص عامة جميعها يجمعها إنها gram negativeيعني
+
+11
+00:00:58,830 --> 00:01:05,790
+مصبوغ الأحمر بـ Gram الـ Stain ويمكن
+
+12
+00:01:05,790 --> 00:01:12,730
+أن تخمر الجلوكوز A اللي تنتج منه الطاقة اللي تنتج
+
+13
+00:01:12,730 --> 00:01:18,110
+الطاقة من السكريات خاصة الجلوكوز في بعضها موجودة
+
+14
+00:01:18,110 --> 00:01:22,730
+في الأمعاء ك Normal Flora و Flora غير مرضية غير
+
+15
+00:01:22,730 --> 00:01:30,160
+مرضية موجودة في أمعاء الإنسان والحيوانوفي بعضها
+
+16
+00:01:30,160 --> 00:01:34,140
+pathogenic يعني مرضى زى السلمونيلا والشيجيلا اللى
+
+17
+00:01:34,140 --> 00:01:38,500
+هتتكلم عليها يبقى يجمعهم ان كلهم يجرعوا negative
+
+18
+00:01:38,500 --> 00:01:42,580
+كلهم بيخمروا الجلوكوزة عشان يطلعوا منه السكر
+
+19
+00:01:42,580 --> 00:01:45,800
+وبعضهم
+
+20
+00:01:45,800 --> 00:01:51,000
+او اكثرهم أفلورا وقليل منهم اللى هو pathogenic
+
+21
+00:01:51,000 --> 00:01:54,700
+يعني مرضى هنبدأ في الاشيراشيا كولاي
+
+22
+00:01:57,450 --> 00:02:03,490
+أه في ناس يعني بيختصروا الاشراشية بحرف ال E E Dot
+
+23
+00:02:03,490 --> 00:02:09,090
+نقطة E Koli يعني اشراشية كولية ايش الميزات بتاعة
+
+24
+00:02:09,090 --> 00:02:14,790
+الاشراشية الخاصة Gram Negative ماشي Short Baselie
+
+25
+00:02:14,790 --> 00:02:21,210
+يعني عصوية طويلة زي هيك يعني هي مبينة انها عصوية
+
+26
+00:02:21,210 --> 00:02:28,570
+طاولة مش ككاىيعني مش زي استخدام الكحكاية واستخدمت
+
+27
+00:02:28,570 --> 00:02:31,910
+كحكاية كراوية لأ هذا عصاوية عشان هيك احنا بيقول
+
+28
+00:02:31,910 --> 00:02:36,670
+عنها biocelli sort of biocelli facultative
+
+29
+00:02:36,670 --> 00:02:40,050
+anaerobic وقولنا facultative anaerobic انها خطيرة
+
+30
+00:02:40,050 --> 00:02:45,730
+في انها بتعيش في oxygen جليل وكتير
+
+31
+00:02:45,730 --> 00:02:54,410
+تستخدم ال glucose يعني بيقولك بتستخدم ال glucose
+
+32
+00:02:55,110 --> 00:03:01,330
+لإنتاج الغاز اه لإنتاج الغاز باستخدام لوكوز لإنتاج
+
+33
+00:03:01,330 --> 00:03:07,090
+طاقة غازية وممكن تستخدم من لوكوز لكتوز اللي هو سكر
+
+34
+00:03:07,090 --> 00:03:15,830
+ثنائي لوكوز اه سكر أحالي و لكتوز سكر ثنائي طيب
+
+35
+00:03:15,830 --> 00:03:18,790
+source of infection الموجود source of infection
+
+36
+00:03:18,790 --> 00:03:24,430
+مصدر العدوى مصدر العدوى من
+
+37
+00:03:26,250 --> 00:03:31,350
+البراز اللى ياخد من قلون الإنسان وقلون الحيوانات
+
+38
+00:03:31,350 --> 00:03:38,530
+الدقيقة الحيوانات الأليفة أقصد domestic الأليفة زى
+
+39
+00:03:38,530 --> 00:03:43,670
+الكطك والكلاب وهذا البراز ينتشر فى التربة وياخده
+
+40
+00:03:43,670 --> 00:03:50,410
+الذباب إلى طعام وشراب الإنسان هي
+
+41
+00:03:50,410 --> 00:03:58,400
+فى الغالب في أمعاء الناس floraflora يعني متعايشة
+
+42
+00:03:58,400 --> 00:04:06,980
+بدون مرض و تستطيع ان تعيش في خارج جسم الإنسان في
+
+43
+00:04:06,980 --> 00:04:12,200
+التربة في الميه ا لمدة و لو أخدنا عينة ميه و
+
+44
+00:04:12,200 --> 00:04:15,600
+حللناها و لجينا فيه E.coli بتكون هذا مؤشر على انه
+
+45
+00:04:15,600 --> 00:04:21,060
+في مجاري عند الميه مثلا ميه النيل ميه البير انه في
+
+46
+00:04:21,060 --> 00:04:27,280
+مجاري او براس وصل ميه البير او ميه النهرطيب ال E
+
+47
+00:04:27,280 --> 00:04:32,240
+coli ايش خطرها بتوديلك لما تعمل مرض تكونش flora
+
+48
+00:04:32,240 --> 00:04:37,620
+مرات تم ال enteritis التهاية بالأمعايا الدقيقة ال
+
+49
+00:04:37,620 --> 00:04:39,920
+enteritis التهاية بالأمعايا الدقيقة طب الأمعايا
+
+50
+00:04:39,920 --> 00:04:54,440
+الغريضة ايش colitis لما اقول colitis c o l i t i s
+
+51
+00:04:58,910 --> 00:05:03,950
+القليتس الأمعاء الغريضة يعني العدوى أو اتهاب
+
+52
+00:05:03,950 --> 00:05:07,770
+الأمعاء الغريضة قليتس الأمعاء الدقيقة انترايتس
+
+53
+00:05:07,770 --> 00:05:11,530
+وانتم لازم تكون عارفين الاناتوم في فرق بين الأمعاء
+
+54
+00:05:11,530 --> 00:05:18,730
+الدقيقة والامعاء الغريضة تنين peritonitis اتهاب
+
+55
+00:05:18,730 --> 00:05:25,330
+غشاء البريتون وهذا الغشاء هو الغشاء الذي يحويأه
+
+56
+00:05:25,330 --> 00:05:31,770
+داخل البطن جميع مستوات البطن من المعدة ومن الأمعاء
+
+57
+00:05:31,770 --> 00:05:37,230
+الذقيقة ومن الأمعاء الغليظة اللي انتوا عارفينها من
+
+58
+00:05:37,230 --> 00:05:45,130
+الأمعاء الغليظة يحتوي أمعاء ذقيقة أو غليظة أه اللي
+
+59
+00:05:45,130 --> 00:05:49,790
+هو المعدة و الكبد طبعا بيكون الكبد هنا
+
+60
+00:05:52,790 --> 00:05:56,790
+البريتوناتس هو غشاء البريتون الذي يحيط بالأحشاء
+
+61
+00:05:56,790 --> 00:06:01,890
+طيب يبتم الانتهاب العمال دقيقة انتهاب اللي هو
+
+62
+00:06:01,890 --> 00:06:06,730
+الغشاء البريتوني سيستايتس انتهاب المسانة البولية
+
+63
+00:06:06,730 --> 00:06:10,450
+معروف أيش المسانة البولية اللتي تتجمع فيها البول
+
+64
+00:06:10,450 --> 00:06:14,590
+وبتطلع من الحالد الأيمن والأسر الأخطر من هذا كله
+
+65
+00:06:14,590 --> 00:06:20,250
+Infantile Diarrheaيعني اللى هو ال .. ال .. الإسهال
+
+66
+00:06:20,250 --> 00:06:24,870
+عند الأطفال يعني أنا رأيت في حياتي كام أطفال ماتوا
+
+67
+00:06:24,870 --> 00:06:29,690
+من الإسهال التالتش راشا كلها يعني هى مصطلعة كتير
+
+68
+00:06:29,690 --> 00:06:34,890
+في خاصة موسم الربيع أول ما يعني يبدأ الدباب يتكاتب
+
+69
+00:06:34,890 --> 00:06:38,330
+في ال .. في الدفء بتاع الربيع تبدأ الدباب ينطنقوا
+
+70
+00:06:38,330 --> 00:06:42,970
+بيه على مصصات الولاد الصغارو بي .. بي .. لما
+
+71
+00:06:42,970 --> 00:06:48,730
+يشربوا الحليب بيصير معهم فنطال دارية و يعني إسهال
+
+72
+00:06:48,730 --> 00:06:54,170
+و تقيق و يموتوا يموتوا من اللي هو فقدان اللي هو
+
+73
+00:06:54,170 --> 00:06:58,450
+السوائل طيب هذه أربعة أمراض أربعة أمراض تعملها
+
+74
+00:06:58,450 --> 00:07:04,830
+شيراشيا كولاي طيب كيف تنتقل للإنسان تنتقل للإنسان
+
+75
+00:07:04,830 --> 00:07:10,210
+عبر الطعام الشراب food and water علشان هيك بقولك
+
+76
+00:07:11,020 --> 00:07:15,500
+waterborne محمولة بالمياه أو foodborne محمولة
+
+77
+00:07:15,500 --> 00:07:20,820
+بالطعام طب ايش اللي بيديب اللي هو البكتيريا للطعام
+
+78
+00:07:20,820 --> 00:07:26,420
+والشراب الذباب طب من وين بيديبوا الذباب من اللي هو
+
+79
+00:07:26,420 --> 00:07:30,080
+المصارف
+
+80
+00:07:30,080 --> 00:07:35,780
+ومن البرادر اللي في الشارع ومن مقالب القمامة
+
+81
+00:07:35,780 --> 00:07:40,820
+والكلام هذا الناس اللي فيهم عدوى خاصةاللي عندهم
+
+82
+00:07:40,820 --> 00:07:45,360
+الأرياف و بياخدوا الحاجة في اللي هو العراق ممكن
+
+83
+00:07:45,360 --> 00:07:49,780
+جدا أن الدباب يكون موجود وياخد من هذا البراج ويطير
+
+84
+00:07:49,780 --> 00:07:53,680
+إلى البيوت ويضع فيه شراب وطعام الناس اللي لما
+
+85
+00:07:53,680 --> 00:08:00,120
+يشربوا ويأكلوا يصيروا عندهم العدوى طيب كيف نشخصها
+
+86
+00:08:00,120 --> 00:08:01,220
+مخبريا
+
+87
+00:08:03,420 --> 00:08:08,820
+أول اشي Stool Culture يعني ناخد عينة من البراز و
+
+88
+00:08:08,820 --> 00:08:13,620
+نعملها مغرعة و المغرعة في التيام او نكتشف ال
+
+89
+00:08:13,620 --> 00:08:18,780
+Antibodies في الدم يبقى كلمة identification التعرف
+
+90
+00:08:18,780 --> 00:08:25,780
+على اللي هو ال Antibodies الأجسام المضادة للإفراش
+
+91
+00:08:25,780 --> 00:08:31,970
+الكولاعي في دم المريض وهذا مهمكيف يعالجها ال
+
+92
+00:08:31,970 --> 00:08:37,450
+treatment بقول انه في الأبناء الأخيرة انه صار فيه
+
+93
+00:08:37,450 --> 00:08:41,830
+resistance للمضادة الحيوية drug resistance عشان
+
+94
+00:08:41,830 --> 00:08:47,310
+هيك يعني كنا زمان بنعطي يعني أمثلة زي تتراتاكلين
+
+95
+00:08:47,310 --> 00:08:52,190
+أكراس ديانو ميسين كلورومتينيكول كفتوميسين عمياني
+
+96
+00:08:52,660 --> 00:08:57,500
+لكن الان صار صعب ان نعمل culture نعطي واحد منهم
+
+97
+00:08:57,500 --> 00:09:02,060
+اجتهادي افتراضي وبنعمل culture يعني مزرعةمن
+
+98
+00:09:02,060 --> 00:09:07,820
+البراضي بتاع الإنسان منذ تلت أيام عشان يبين ليه ال
+
+99
+00:09:07,820 --> 00:09:11,340
+antibiotic الأحسن ال antibiotic الأحسن الإشعاراش
+
+100
+00:09:11,340 --> 00:09:16,120
+الكولاي خاصة في حياة الأطفال لأن منعتهم ضعيفة فهذه
+
+101
+00:09:16,120 --> 00:09:20,400
+أول واحدة الإشعاراش الكولاي من اللي هو مسببات
+
+102
+00:09:20,400 --> 00:09:25,040
+التهاب الأماء الدقيقة الثانية Protease Protease
+
+103
+00:09:25,040 --> 00:09:33,630
+يعني تتميز إنها gram negativebasal lie هي gram
+
+104
+00:09:33,630 --> 00:09:37,910
+negative بس
+
+105
+00:09:37,910 --> 00:09:45,870
+هي عصوية ومتنية شوية يعني مش مستقيمة ميا ميا يعني
+
+106
+00:09:45,870 --> 00:09:52,710
+تجيب فيها شوية انحلاق بسيطة slightly curved basal
+
+107
+00:09:52,710 --> 00:09:57,590
+lie فكرت ان انا يا روب اه قلنا انت ليش في اكسجين
+
+108
+00:09:57,590 --> 00:10:05,940
+عالي واقعي وانا خاطر منهابتنتج غاز من سكر اسمه
+
+109
+00:10:05,940 --> 00:10:12,320
+ساكروز ساكروز و مالتوز سكريات فنائية و بتنظف منهم
+
+110
+00:10:12,320 --> 00:10:17,860
+غاز يعني مش من الجلوكوز من سكريات أخرى أعقل من
+
+111
+00:10:17,860 --> 00:10:24,240
+اللي هو الجلوكوز وتستطيع الحركة موتايل تتنقل يعني
+
+112
+00:10:24,240 --> 00:10:29,560
+في الأراضي الزراعية في الميهو بتعيش في colonies
+
+113
+00:10:29,560 --> 00:10:33,740
+colonies يعني مستعمرات بكتيرية خاصة لما نفتها في
+
+114
+00:10:33,740 --> 00:10:41,200
+طبق أجار طبق بكتيري في طهائم طيب من وين ال .. ال
+
+115
+00:10:41,200 --> 00:10:45,140
+.. ال .. مصدر أدوى source of infection قولنا أما
+
+116
+00:10:45,140 --> 00:10:51,540
+الإنسان المعدي اللي هو فيه الاشي لما يكون حط يعني
+
+117
+00:10:51,540 --> 00:10:56,310
+البولاج هذا وصل الميه أو التربة ال soil التربةطيب
+
+118
+00:10:56,310 --> 00:11:03,030
+الأمراض المسببة disease اه اللي من المرض او من
+
+119
+00:11:03,030 --> 00:11:09,850
+السلالات المرضية اللتي يعني تسبب المرض اول اشي
+
+120
+00:11:09,850 --> 00:11:14,950
+بتعمل eye infection كتير من عيون الناس بيجوا فيها
+
+121
+00:11:14,950 --> 00:11:20,590
+يعني التهابات وعدوى واحنا بنعرفها هنا E coliair
+
+122
+00:11:20,590 --> 00:11:25,830
+infection أو لو قيت على الأذن ممكن تعمل air يعني
+
+123
+00:11:25,830 --> 00:11:30,430
+اللي هو العدوى في الأذن ممكن عند الأطفال تعمل
+
+124
+00:11:30,430 --> 00:11:34,350
+summer diarrhea summer diarrhea يعني زي ما عملت ال
+
+125
+00:11:34,350 --> 00:11:38,690
+E coli هذه برضه بتعمل نفس الشي عند الأطفال أسهال
+
+126
+00:11:38,690 --> 00:11:42,790
+الأطفال وهذا الأسهال اللي بيعمل فقد للسوائل
+
+127
+00:11:42,790 --> 00:11:47,690
+unattract infection لو دخلت خاصة في الأطفال الصغار
+
+128
+00:11:47,690 --> 00:11:53,460
+خاصة الإناتمن البراز إلى البول في الحفاظة يعني لو
+
+129
+00:11:53,460 --> 00:12:01,780
+كان يعني عند الطفل أو الطفلة في الحفاظة و هو نازل
+
+130
+00:12:01,780 --> 00:12:07,420
+البراز و دخل من فتحة البول إلى الأمام ممكن جدا انه
+
+131
+00:12:07,420 --> 00:12:11,820
+يعمل unit tract infection التهيبات مجاري البول
+
+132
+00:12:11,820 --> 00:12:17,630
+supportive abscess ممكن يعمل دماملخاصة في الجزء
+
+133
+00:12:17,630 --> 00:12:23,390
+الأسفل من الجسم وفيها دي صدير وفيها صدير وكما
+
+134
+00:12:23,390 --> 00:12:29,010
+سيستريتس اتهابات او عدوة البولية و Pileonephritis
+
+135
+00:12:29,010 --> 00:12:33,130
+الأعلى حوض الكيلية يعني معروف ان الكيلية زي هيك
+
+136
+00:12:33,130 --> 00:12:41,450
+وبعدين الكيلية إلى حوض هذا الموقع اسمه حوض الكيلية
+
+137
+00:12:41,450 --> 00:12:47,360
+الحوض الكلوي اللي هو هذابحوض الكلية بحوض الكلية
+
+138
+00:12:47,360 --> 00:12:54,360
+اللى هى أعلى من اللى هو الوريتر اللى هو الحالب
+
+139
+00:12:54,360 --> 00:12:58,980
+بحوض الكلية يبقى التهاب المسان البولية اللى بتكون
+
+140
+00:12:58,980 --> 00:13:04,160
+تحت هنا يصب فيها الحالب والتهاب بحوض الكلية اللى
+
+141
+00:13:04,160 --> 00:13:10,540
+أعلى منه طيب البكتيريا اللى بتعمل أمعاد دقيقة عدوى
+
+142
+00:13:10,540 --> 00:13:18,550
+شجلة فالشجلةتشبههم انها جرام نيجاتيف اه و فكالتاتب
+
+143
+00:13:18,550 --> 00:13:25,370
+انروب زيهم برضه يعني لها هوية اختيارية و بتستخدم
+
+144
+00:13:25,370 --> 00:13:31,970
+الهيلوكوز عشان تطلع منه اسد يعني الطاقة بتاعتها
+
+145
+00:13:31,970 --> 00:13:39,130
+حامض مشغلز تطلع اسد و لا تستطيع الحركة نانو موتايل
+
+146
+00:13:39,130 --> 00:13:43,980
+يعني مالهاش فلاجلة مثلا لاستطيع الحركةمن أي نسبة
+
+147
+00:13:43,980 --> 00:13:51,640
+العدوى ال source من الحالات المرضية والحالات ال
+
+148
+00:13:51,640 --> 00:13:55,400
+carriers او subclinical التي لا يبدو عليها المرض
+
+149
+00:13:55,400 --> 00:14:06,680
+طبعا الأطعمة الملوثة بالبكتيريا اه ازاي ال food و
+
+150
+00:14:06,680 --> 00:14:11,080
+ال fingers و ال pumice يعني ال pumice اللي هو
+
+151
+00:14:12,030 --> 00:14:16,470
+مختصات او اشياء مختصة فيها المريض زي فواط المريض
+
+152
+00:14:16,470 --> 00:14:22,430
+ملابس المريض كباية المريض اي حاجة يعني مناشف
+
+153
+00:14:22,430 --> 00:14:27,850
+المريض يستطيع الدباب ان ينقل من هذه الأشياء الى
+
+154
+00:14:27,850 --> 00:14:32,270
+طعام وشرب الأدمين وسير ومعدين هذا ما اتكلم عن مصدر
+
+155
+00:14:32,270 --> 00:14:37,030
+يعني source of infection يعني مصدر infectionالمصدر
+
+156
+00:14:37,030 --> 00:14:42,030
+هم العيانين بالأحرى والناس اللي مش مبين عليهم ممكن
+
+157
+00:14:42,030 --> 00:14:49,850
+الذباب يطير من برازهم يطير من كيهم يطير من ملابسهم
+
+158
+00:14:49,850 --> 00:14:56,790
+او من يعني افرازاتهم منشفهم وييجي على طعام وشرب
+
+159
+00:14:56,790 --> 00:15:04,430
+الأدمين ويبلعوه ويطير فيهم المرض بتاع الشيجلة اسم
+
+160
+00:15:04,430 --> 00:15:10,370
+شيجل لوزالشيجاللوزس في ناس بيسموه bacillary
+
+161
+00:15:10,370 --> 00:15:14,830
+dysentery الدزونتاليا الباسلية يعني عشان هي
+
+162
+00:15:14,830 --> 00:15:21,950
+بكتيريا باسلائي أو شيجاللوزس طيب هذه الأخطر ان
+
+163
+00:15:21,950 --> 00:15:27,290
+الشيجالة إلها إكزوتوكسين يعني إلها سم سفر ذوكارجي
+
+164
+00:15:27,290 --> 00:15:32,350
+وهذا قوي جدا يمزق الرسالة المخاطرة معاها الدقيقة
+
+165
+00:15:32,350 --> 00:15:38,390
+وبيجيب دمبتصير مجوزة بيصير لها إذابة طيب نشوف
+
+166
+00:15:38,390 --> 00:15:43,250
+الأعراض بتاع الشيجين اليوزس الأعراض bloody ذيارية
+
+167
+00:15:43,250 --> 00:15:49,510
+بفعل اكزيتوكسين يعني يعني يعني عدوة فيها دم أو
+
+168
+00:15:49,510 --> 00:15:55,550
+سقال دموي سقال دموي هنا abdomen cramp تقلص في
+
+169
+00:15:55,550 --> 00:16:01,020
+البطن تقلص في البطن يعني ماغس شديد مع قلمو مع
+
+170
+00:16:01,020 --> 00:16:07,520
+fever اللي هو يعني سخونة و vomiting تقيق و مع تقيق
+
+171
+00:16:07,520 --> 00:16:14,260
+يبقى احنا عندنا تقيق و إسهال الطيارية هي نجرناهم
+
+172
+00:16:14,260 --> 00:16:23,740
+مع مغص و سخونة و ألم طيب في الحلقات الخطيرة بيبدأ
+
+173
+00:16:23,740 --> 00:16:31,480
+يصير بص يعني التخرجات صارت فيها صليبو نزل مع الدم
+
+174
+00:16:31,480 --> 00:16:40,160
+الصديق طيب هو حقيقة أخطر شئ ان هو يمزق الرشاة
+
+175
+00:16:40,160 --> 00:16:45,640
+المخاطر المبطن للأمعاء و بيخليه نكروتك مذاب و
+
+176
+00:16:45,640 --> 00:16:51,460
+ulcerated و فيه تقرر و هذا بيعمل bloody ذيارية
+
+177
+00:16:51,460 --> 00:16:56,440
+bloody ذيارية يعني إسهال دموي و أحيانا صدو ممبرين
+
+178
+00:16:56,440 --> 00:17:02,180
+صدو ممبرين أي رشاة كاربداخل جدار الأمعاء الدقيقة
+
+179
+00:17:02,180 --> 00:17:06,040
+همتكلم انا معاها الدقيقة و لسه على الغاليظة كيف
+
+180
+00:17:06,040 --> 00:17:12,360
+نشخص stool culture يعني لازم ناخد براز المريض اللي
+
+181
+00:17:12,360 --> 00:17:16,380
+معاه إسهال دموي و نفطه تلت أيام في مزرعة و إيش
+
+182
+00:17:16,380 --> 00:17:21,520
+المزرعة بتطلع احنا نتمنى كانوا زمان بيعطوا موركبات
+
+183
+00:17:21,520 --> 00:17:27,240
+سالفة اه و try metaprim وهي الإفتراضيةلكن المدرعة
+
+184
+00:17:27,240 --> 00:17:32,140
+هي الأساس بعد تلت أيام انطلع في antibiotic قوي
+
+185
+00:17:32,140 --> 00:17:37,800
+بنعطيه في ناس بعتوا attenuated vaccine ال vaccine
+
+186
+00:17:37,800 --> 00:17:42,860
+هذا يعني تطعيم بنعطي الأصحاء لو في بلد يعني في
+
+187
+00:17:42,860 --> 00:17:48,060
+شجلة كتير فاحنا بنطعم الأصحاء عشان ال vaccine هذا
+
+188
+00:17:48,060 --> 00:17:52,860
+بتطلعاللي هو antibodies يعني أجسام مضاردة لو إجت
+
+189
+00:17:52,860 --> 00:17:56,860
+الشجلة بتلاقي الأجسام المضاردة مستنياها فلا تفتك
+
+190
+00:17:56,860 --> 00:18:02,700
+في أمعاء المريض اللي عنده vaccine اللي عنده تطعيم
+
+191
+00:18:02,700 --> 00:18:08,520
+زي اللي غير مطعم السالمونيلا
+
+192
+00:18:08,520 --> 00:18:13,520
+نمرة أربعة هذه حقيقة اللي بتعمل حمّة في إيد تسمع
+
+193
+00:18:13,520 --> 00:18:16,860
+عليه حمّة في إيد السالمونيلا
+
+194
+00:18:17,800 --> 00:18:24,760
+هي جرام نيجاتيف بكتيريا و motile و فقط تبقى الهروب
+
+195
+00:18:24,760 --> 00:18:32,360
+يعني تشبه اللي قبلها من أي نتائج العدوى من المرضى؟
+
+196
+00:18:32,360 --> 00:18:36,700
+لما نقول clinical يعني المرضى اللي بيشتكوا من ال
+
+197
+00:18:36,700 --> 00:18:42,040
+aepoid و subclinical او من اصابة خفيفة او carrier
+
+198
+00:18:42,040 --> 00:18:45,900
+اللي هو اللي حاملين للبكتيريا
+
+199
+00:18:46,880 --> 00:18:53,740
+دون أن يبدو عليهم مرض كارير خاصة بعد الشفاء طبعا
+
+200
+00:18:53,740 --> 00:18:58,760
+البراج هو المشكلة لأنه بيحملوا الذباب يبقى الذباب
+
+201
+00:18:58,760 --> 00:19:06,560
+ال flies بيحمل من أدافر وأصابع المريض الملوثة
+
+202
+00:19:06,560 --> 00:19:13,980
+بالبراج ومن طعامه ومن منشبته ومن إفرازاته ومناديره
+
+203
+00:19:13,980 --> 00:19:21,070
+وبينجلها إلىالpopulation إلى الشعب بنجيلها spread
+
+204
+00:19:21,070 --> 00:19:24,590
+ده بس اللي هي يعني انشرها إلى الشعب يبقى هو المصدر
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+هو المريض الذي يحمل هذا النوع من البكينيا كيف يتم
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+نقل العدوى mode of infection كيف يتم نقل العدوى
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+بقول من الميه ومن الحليب ومن اللي هو الطعام food
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+barn water barn و milk barnإيه ده وصف البكتيريا
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+عبر الذباب عبر الذباب بقول إنه ال salmonella
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+pathogenic يعني بتعمل مرض و الغريب إن هي مفكرة
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+00:20:01,130 --> 00:20:07,750
+تستطيع أن تفلت من الفلتوز اللي هو نظام اللي هو
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+الابتلاع اللي هو الخلايا البيضاءالمتعادلة في جسم
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+الإنسان لاتستطيع الخلايا البيضاء أن تلتهمها وإذا
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+التهمتها تفضل حية داخلها وتتحرك alive inside her
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+macrophage وبتعمل Intracereal infection لها
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+216
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+ولاتموت يعني تقدر تجد عليها كما تقضي على بكتيريا
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+217
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+أخرى إيش هي الأجناس بتاع بكتيريا الـPepoid في تلت
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+218
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+أجناس سالمونيلا طيفيسلمونيلا بارا تيفي سلمونيلا
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+219
+00:20:46,040 --> 00:20:54,520
+انتراي تي ديز انتراي تي ديز انتراي
+
+220
+00:20:54,520 --> 00:20:54,820
+تي ديز انتراي تي ديز انتراي تي ديز انتراي تي ديز
+
+221
+00:20:54,820 --> 00:20:55,380
+انتراي تي ديز انتراي تي ديز انتراي تي ديز انتراي
+
+222
+00:20:55,380 --> 00:20:56,640
+تي ديز انتراي تي ديز انتراي تي ديز انتراي تي ديز
+
+223
+00:20:56,640 --> 00:21:11,300
+انتراي تي ديز انتراي تي ديز انتراي تي ديز
+
+224
+00:21:11,300 --> 00:21:17,410
+انالسلمونيلا in 30 days بتعمل food poisoning يعني
+
+225
+00:21:17,410 --> 00:21:23,090
+تسمم غذائي بتعملش طيف و إيد ولا برط في إيد بتعمل
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+00:21:23,090 --> 00:21:32,070
+تسمم غذائي عن طريق السموم طيب ال slide هذه باللغة
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+227
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+العربية وهذه باللغة العربية معكوا homework يعني ان
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+228
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+انتوا تقرؤوها يعني هيبتساعدك على فهم كيف يعني
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+229
+00:21:43,580 --> 00:21:49,340
+تنتقل العدوى وصوب المقاية وكذلك يعني طرق العدوى و
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+230
+00:21:49,340 --> 00:21:54,900
+الأعراض عراض الإصابة بالتفؤيد ضروري تقرأوا ال
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+231
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+slide هذا و ال slide هذا معاكم homeworkهذه
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+232
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+السلمونيلا طيبى وهذه السلمونيلا بارا طيبى ملاحظين
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+انهم أحمر يعني انهم gram negative بسي لاي طيب نجي
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+234
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+ليه تفوقيت fever ايش أعراض اعراض او clinical
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+235
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+picture يعني clinical picture العلامات والأعراض مع
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+236
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+بعض اسمها clinical picture تحت تفوقيتأول اشي بيبدأ
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+المريض general weakness يعني ضعف عام هزال بعد أيام
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+238
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+بيبدأ معاه high fever high fever ال high fever هذه
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+239
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+يعني عجيبة step later فاشر درجات السلم يعني تيجي
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+240
+00:22:43,530 --> 00:22:52,150
+الممرضة اول يوم بتجيها سبعة و تلاتين سبعة و تلاتين
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+241
+00:22:52,150 --> 00:22:58,200
+تاني يوم تمانيةتلافين اتاره يوم تسعة و تلافين رابع
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+242
+00:22:58,200 --> 00:23:07,340
+يوم اربعين لو احنا جينا نوصل هيك هيك هيك
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+243
+00:23:07,340 --> 00:23:14,900
+هيك هيك هذا اسمه strip ladder strip ladder يعني
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+244
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+درجات السلم كأنك انت بتطلع على سلم الحرارة كل يوم
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+245
+00:23:22,090 --> 00:23:27,870
+بتزيد شوية بتزيد شوية بتزيد شوية لما نشبك النقاط
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+246
+00:23:27,870 --> 00:23:32,770
+في بعضها بنلاقي حالنا احنا ماشيين ع درج مدت اربع
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+247
+00:23:32,770 --> 00:23:38,910
+الى خمس أيام مش من اول يوم ال vagina weakness high
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+248
+00:23:38,910 --> 00:23:45,010
+fever بعدين ال rash طفح جلدي هنشوفه يظهر على البطن
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+249
+00:23:45,010 --> 00:23:48,630
+و على الصدر على البطن و الصدر يعني يبدو هاي الطفح
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+250
+00:23:48,630 --> 00:23:53,950
+الجلدي هاي الطفح الجلديالطفل الجلدي على الظهر و
+
+251
+00:23:53,950 --> 00:23:59,150
+على البط من أمام و من الخلف وهي اللي بوستي بلاذر
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+252
+00:23:59,150 --> 00:24:03,750
+fashion زي ما قولنا يعني هي هتبدأ هيك و بعدين تبدأ
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+253
+00:24:03,750 --> 00:24:10,550
+تطلع درجات و درجات لو انا يعني بدأ اوصلها لهيك
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+254
+00:24:10,550 --> 00:24:17,650
+وهذه هيك وهذه هيك بيبين انه انا ماشي درجة بعد رشة
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+255
+00:24:17,650 --> 00:24:22,360
+الطفل الجلدي sweeping عرقو chills راجل فات يعني
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+256
+00:24:22,360 --> 00:24:31,060
+دورجوف بعد هيك drowsiness يعني نوع من الضعف العام
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+257
+00:24:31,060 --> 00:24:40,840
+و يعني دوخة و aching aching ألم في الأقدام و ألم
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+258
+00:24:40,840 --> 00:24:45,580
+في اليد يعني الطرف العلو السفلي بيلاقي فيه أن هو
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+259
+00:24:45,580 --> 00:24:52,330
+فيه ألم بعدين لو ماتعالجشبيصير فيه التهيبات في
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+260
+00:24:52,330 --> 00:24:56,950
+العظم و التهيبات في الطفال في ال cases advanced
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+261
+00:24:56,950 --> 00:25:05,650
+لما تتقدم الكون في النهايات بقول
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+262
+00:25:05,650 --> 00:25:09,350
+انه كتير الحالات بيصيرها recovery a natural
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+263
+00:25:09,350 --> 00:25:18,520
+recovery يعني natural recovery يعني بيشفى لحالهلكن
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+264
+00:25:18,520 --> 00:25:22,120
+افضل انه يتعالج و الناس كانوا بيعطوه امبيسيلين
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+265
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+مركبات البرنسالين و مركبات الكلورامفينيكل
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+266
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+كلورامفينيكل عشان يجدوا على اللي هو الاعراض في
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+267
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+vaccine يعني بنعطيه اسمه تاب فاكسين تاب فاكسين
+
+268
+00:25:47,670 --> 00:25:57,270
+وهذا بيعمل immunity للناس قبل ان يصابوا ال بطل فى
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+269
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+ايد مش مثل فى ايد بيقول انه هتلاقي فيه ضيارية اسهل
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+270
+00:26:04,250 --> 00:26:07,590
+و mild fever يعني السخونة بتاعته مش step ladder
+
+271
+00:26:07,590 --> 00:26:12,050
+وعالية لأ والراشد زى الأولى بس اجل على ال chest
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+272
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+بيلاجيه الراشد طبعا هتيجي اجلوالعلاج الأفضل انه ال
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+273
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+vaccine عشان في أجسام مضادة التسخيص بتاع التفؤيد
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+274
+00:26:25,280 --> 00:26:32,000
+والبراتفؤيد زمان stool specimen يعني عينة براز من
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+275
+00:26:32,000 --> 00:26:36,680
+الإسهال اللي باقولها وعينة بول لعشان يكون مصاب
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+276
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+بالكهابات للبولو بنعمل culture للبراز خاصة لما
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+277
+00:26:43,070 --> 00:26:50,150
+يكون سخن و ممكن ناكل من الدم عشان نكتشف انه فيه
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+278
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+antipodes ولا لا سالمونيلا تفويد و براتفويد هذه ال
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+279
+00:26:56,690 --> 00:27:01,190
+antipodes ده و اكتشفناها اسمها Vidal test هو
+
+280
+00:27:01,190 --> 00:27:06,830
+اكتشاف لسان مضادة من المرضى من المرضى ليه لهو هذا
+
+281
+00:27:07,320 --> 00:27:12,620
+المرض تفويت او الفارع تفويت انا يعني اكتفي بهذا
+
+282
+00:27:12,620 --> 00:27:17,920
+القدر متوقف عند اللي هو ال Vibrio cholera يعني على
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+283
+00:27:17,920 --> 00:27:23,640
+اساس انه ما نطول المحاضرة عن هيك ويعني متأمل من
+
+284
+00:27:23,640 --> 00:27:27,320
+الله عز و جل انه تكونوا انتوا استفدتم من هذه
+
+285
+00:27:27,320 --> 00:27:31,060
+المحاضرة تالتة عشرة و اللقاء في المحاضرة راضي عشرة
+
+286
+00:27:31,060 --> 00:27:31,400
+قريبا
+
diff --git a/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/qoFbPnY6GRo_raw.json b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/qoFbPnY6GRo_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..2be9913f8edc8d70aee09d41e3c563cc6827eab6
--- /dev/null
+++ b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/qoFbPnY6GRo_raw.json
@@ -0,0 +1 @@
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إكزوتوكسين يعني إلها سم سفر ذوكارجي وهذا قوي جدا يمزق الرسالة المخاطرة معاها الدقيقة وبيجيب دم", "tokens": [6027, 8592, 1829, 7435, 6027, 1211, 2407, 11622, 3794, 8978, 8717, 32277, 4724, 1829, 38251, 2407, 3224, 6857, 46367, 15243, 14278, 88, 32748, 11622, 11536, 2655, 6027, 25528, 29739, 32277, 1211, 10632, 37495, 22653, 6225, 8592, 7649, 39896, 4724, 4117, 2655, 13546, 25528, 4724, 32277, 1211, 16373, 1829, 34051, 13412, 1829, 7435, 6027, 1211, 2407, 11622, 3794, 23032, 1829, 3555, 29538, 16247, 9778, 9566, 2288, 16472, 25124, 1829, 7435, 6027, 3660, 11933, 1211, 11296, 11933, 4117, 11622, 35473, 2407, 4117, 3794, 9957, 37495, 22653, 11933, 1211, 11296, 8608, 2304, 8608, 5172, 2288, 29910, 2407, 4117, 9640, 7435, 1829, 37037, 15730, 12174, 45865, 10874, 28259, 7251, 2304, 11622, 4587, 34892, 3794, 6027, 3660, 9673, 9778, 41193, 25720, 20449, 995, 11296, 32748, 38436, 28671, 4032, 21292, 7435, 1829, 3555, 11778, 2304], "avg_logprob": -0.3456730643144021, "compression_ratio": 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{"start": 914.83, "end": 915.39, "word": " بكتيريا", "probability": 0.8224609375}, {"start": 915.39, "end": 916.07, "word": " باسلائي", "probability": 0.6163330078125}, {"start": 916.07, "end": 916.87, "word": " أو", "probability": 0.497802734375}, {"start": 916.87, "end": 918.25, "word": " شيجاللوزس", "probability": 0.88287353515625}, {"start": 918.25, "end": 919.73, "word": " طيب", "probability": 0.8460286458333334}, {"start": 919.73, "end": 920.63, "word": " هذه", "probability": 0.58837890625}, {"start": 920.63, "end": 921.55, "word": " الأخطر", "probability": 0.949462890625}, {"start": 921.55, "end": 921.95, "word": " ان", "probability": 0.5625}, {"start": 921.95, "end": 922.61, "word": " الشيجالة", "probability": 0.80244140625}, {"start": 922.61, "end": 923.39, "word": " إلها", "probability": 0.6019083658854166}, {"start": 923.39, "end": 924.21, "word": " إكزوتوكسين", "probability": 0.70050048828125}, {"start": 924.21, "end": 924.45, "word": " يعني", "probability": 0.9189453125}, {"start": 924.45, "end": 924.83, "word": " إلها", "probability": 0.8390299479166666}, {"start": 924.83, "end": 925.49, "word": " سم", "probability": 0.786376953125}, {"start": 925.49, "end": 926.51, "word": " سفر", "probability": 0.509521484375}, {"start": 926.51, "end": 927.29, "word": " ذوكارجي", "probability": 0.7830810546875}, {"start": 927.29, "end": 928.03, "word": " وهذا", "probability": 0.908935546875}, {"start": 928.03, "end": 928.81, "word": " قوي", "probability": 0.8154296875}, {"start": 928.81, "end": 929.27, "word": " جدا", "probability": 0.987060546875}, {"start": 929.27, "end": 930.47, "word": " يمزق", "probability": 0.933837890625}, {"start": 930.47, "end": 930.99, "word": " الرسالة", "probability": 0.6480712890625}, {"start": 930.99, "end": 931.59, "word": " المخاطرة", "probability": 0.85107421875}, {"start": 931.59, "end": 931.89, "word": " معاها", "probability": 0.5547688802083334}, {"start": 931.89, "end": 932.35, "word": " الدقيقة", "probability": 0.9300130208333334}, {"start": 932.35, "end": 933.55, "word": " وبيجيب", "probability": 0.71982421875}, {"start": 933.55, "end": 933.79, "word": " دم", "probability": 0.984375}], "temperature": 1.0}, {"id": 35, "seek": 96011, "start": 934.03, "end": 960.11, "text": "بتصير مجوزة بيصير لها إذابة طيب نشوف الأعراض بتاع الشيجين اليوزس الأعراض bloody ذيارية بفعل اكزيتوكسين يعني يعني يعني عدوة فيها دم أو سقال دموي سقال دموي هنا abdomen cramp تقلص في البطن تقلص في البطن يعني ماغس شديد مع قلم", "tokens": [3555, 2655, 9381, 13546, 3714, 7435, 2407, 11622, 3660, 4724, 1829, 9381, 13546, 5296, 11296, 11933, 15730, 49401, 23032, 1829, 3555, 8717, 8592, 38688, 16247, 3615, 2288, 46958, 39894, 45761, 25124, 1829, 7435, 9957, 2423, 1829, 2407, 11622, 3794, 16247, 3615, 2288, 46958, 18938, 29910, 1829, 9640, 10632, 4724, 5172, 30241, 1975, 4117, 11622, 36081, 2407, 4117, 3794, 9957, 37495, 22653, 37495, 22653, 37495, 22653, 6225, 3215, 2407, 3660, 8978, 11296, 11778, 2304, 34051, 8608, 4587, 6027, 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"probability": 0.947509765625}, {"start": 939.31, "end": 939.81, "word": " بتاع", "probability": 0.785400390625}, {"start": 939.81, "end": 940.19, "word": " الشيجين", "probability": 0.543060302734375}, {"start": 940.19, "end": 940.71, "word": " اليوزس", "probability": 0.625927734375}, {"start": 940.71, "end": 942.13, "word": " الأعراض", "probability": 0.9647216796875}, {"start": 942.13, "end": 942.63, "word": " bloody", "probability": 0.28955078125}, {"start": 942.63, "end": 943.25, "word": " ذيارية", "probability": 0.78021240234375}, {"start": 943.25, "end": 944.71, "word": " بفعل", "probability": 0.8680013020833334}, {"start": 944.71, "end": 945.47, "word": " اكزيتوكسين", "probability": 0.715545654296875}, {"start": 945.47, "end": 945.93, "word": " يعني", "probability": 0.885009765625}, {"start": 945.93, "end": 946.77, "word": " يعني", "probability": 0.832275390625}, {"start": 946.77, "end": 947.27, "word": " يعني", "probability": 0.753662109375}, {"start": 947.27, "end": 947.99, "word": " عدوة", "probability": 0.86865234375}, {"start": 947.99, "end": 948.69, "word": " فيها", "probability": 0.95458984375}, {"start": 948.69, "end": 948.93, "word": " دم", "probability": 0.9873046875}, {"start": 948.93, "end": 949.51, "word": " أو", "probability": 0.61376953125}, {"start": 949.51, "end": 950.17, "word": " سقال", "probability": 0.5506998697916666}, {"start": 950.17, "end": 950.63, "word": " دموي", "probability": 0.9542643229166666}, {"start": 950.63, "end": 951.25, "word": " سقال", "probability": 0.875}, {"start": 951.25, "end": 952.15, "word": " دموي", "probability": 0.97216796875}, {"start": 952.15, "end": 952.51, "word": " هنا", "probability": 0.16259765625}, {"start": 952.51, "end": 953.09, "word": " abdomen", "probability": 0.55712890625}, {"start": 953.09, "end": 953.85, "word": " cramp", "probability": 0.3680419921875}, {"start": 953.85, "end": 955.17, "word": " تقلص", "probability": 0.980712890625}, {"start": 955.17, "end": 955.55, "word": " في", "probability": 0.96044921875}, {"start": 955.55, "end": 955.97, "word": " البطن", "probability": 0.813720703125}, {"start": 955.97, "end": 956.53, "word": " تقلص", "probability": 0.9342041015625}, {"start": 956.53, "end": 956.65, "word": " في", "probability": 0.974609375}, {"start": 956.65, "end": 957.17, "word": " البطن", "probability": 0.9939778645833334}, {"start": 957.17, "end": 957.95, "word": " يعني", "probability": 0.965087890625}, {"start": 957.95, "end": 958.29, "word": " ماغس", "probability": 0.7056884765625}, {"start": 958.29, "end": 959.11, "word": " شديد", "probability": 0.8421223958333334}, {"start": 959.11, "end": 959.73, "word": " مع", "probability": 0.97802734375}, {"start": 959.73, "end": 960.11, "word": " قلم", "probability": 0.744140625}], "temperature": 1.0}, {"id": 36, "seek": 99018, "start": 960.52, "end": 990.18, "text": "و مع fever اللي هو يعني سخونة و vomiting تقيق و مع تقيق يبقى احنا عندنا تقيق و إسهال الطيارية هي نجرناهم مع مغص و سخونة و ألم طيب في الحلقات الخطيرة بيبدأ يصير بص يعني التخرجات صارت فيها صليب", "tokens": [2407, 20449, 18277, 13672, 1829, 31439, 37495, 22653, 8608, 9778, 11536, 3660, 4032, 46234, 6055, 38436, 4587, 4032, 20449, 6055, 38436, 4587, 7251, 3555, 4587, 7578, 1975, 5016, 8315, 43242, 8315, 6055, 38436, 4587, 4032, 11933, 3794, 3224, 6027, 41950, 1829, 9640, 10632, 39896, 8717, 7435, 2288, 8315, 16095, 20449, 3714, 17082, 9381, 4032, 8608, 9778, 11536, 3660, 4032, 5551, 19528, 23032, 1829, 3555, 8978, 21542, 1211, 4587, 9307, 33962, 9566, 48923, 4724, 1829, 44510, 10721, 7251, 9381, 13546, 4724, 9381, 37495, 22653, 16712, 34740, 7435, 9307, 20328, 9640, 2655, 8978, 11296, 20328, 20292, 3555], "avg_logprob": -0.21272786116848388, "compression_ratio": 1.7010309278350515, "no_speech_prob": 0.0, "words": [{"start": 960.52, "end": 960.78, "word": "و", "probability": 0.58203125}, {"start": 960.78, "end": 961.02, "word": " مع", "probability": 0.48974609375}, {"start": 961.02, "end": 961.76, "word": " fever", 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0.9295247395833334}, {"start": 968.36, "end": 968.9, "word": " عندنا", "probability": 0.990966796875}, {"start": 968.9, "end": 969.8, "word": " تقيق", "probability": 0.9632161458333334}, {"start": 969.8, "end": 970.98, "word": " و", "probability": 0.89892578125}, {"start": 970.98, "end": 971.68, "word": " إسهال", "probability": 0.79315185546875}, {"start": 971.68, "end": 972.82, "word": " الطيارية", "probability": 0.8353271484375}, {"start": 972.82, "end": 973.5, "word": " هي", "probability": 0.529296875}, {"start": 973.5, "end": 974.26, "word": " نجرناهم", "probability": 0.76875}, {"start": 974.26, "end": 975.54, "word": " مع", "probability": 0.89599609375}, {"start": 975.54, "end": 975.94, "word": " مغص", "probability": 0.88232421875}, {"start": 975.94, "end": 976.1, "word": " و", "probability": 0.72802734375}, {"start": 976.1, "end": 976.58, "word": " سخونة", "probability": 0.965576171875}, {"start": 976.58, "end": 977.38, "word": " و", "probability": 0.9287109375}, {"start": 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أربعة هذه حقيقة اللي بتعمل حمّة في إيد تسمع عليه حمّة في إيد السالمونيلا", "tokens": [6027, 20292, 31439, 28356, 37495, 22653, 5551, 7435, 3794, 10943, 3714, 11242, 9640, 41891, 45164, 11933, 7435, 2655, 25124, 7435, 37977, 39894, 15040, 38436, 16247, 7435, 3794, 10943, 9673, 11242, 9640, 41891, 3714, 14851, 22653, 995, 11296, 6156, 15040, 6055, 5172, 2655, 4117, 8978, 5551, 2304, 3615, 16606, 9673, 16572, 11242, 13672, 1829, 43242, 3224, 7007, 13672, 1829, 43242, 3224, 6055, 9566, 3615, 32640, 30767, 1829, 13672, 1829, 32771, 13546, 3714, 9566, 25957, 21136, 6027, 2304, 11536, 1829, 15040, 8717, 2304, 25720, 5551, 25513, 27884, 29538, 11331, 38436, 28671, 13672, 1829, 39894, 25957, 1211, 11331, 2304, 11703, 3660, 8978, 11933, 25708, 6055, 38251, 3615, 47356, 11331, 2304, 11703, 3660, 8978, 11933, 25708, 21136, 45340, 11536, 1829, 15040], "avg_logprob": -0.21001058993703228, "compression_ratio": 1.9210526315789473, "no_speech_prob": 0.0, "words": [{"start": 1069.08, "end": 1069.4, 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"probability": 0.8548177083333334}, {"start": 1590.62, "end": 1591.22, "word": " براز", "probability": 0.8577473958333334}, {"start": 1591.22, "end": 1592.0, "word": " من", "probability": 0.9736328125}, {"start": 1592.0, "end": 1592.76, "word": " الإسهال", "probability": 0.910400390625}, {"start": 1592.76, "end": 1592.88, "word": " اللي", "probability": 0.747802734375}, {"start": 1592.88, "end": 1593.26, "word": " باقولها", "probability": 0.549957275390625}, {"start": 1593.26, "end": 1594.34, "word": " وعينة", "probability": 0.9521484375}, {"start": 1594.34, "end": 1594.74, "word": " بول", "probability": 0.6175537109375}, {"start": 1594.74, "end": 1595.54, "word": " لعشان", "probability": 0.8876953125}, {"start": 1595.54, "end": 1595.92, "word": " يكون", "probability": 0.989501953125}, {"start": 1595.92, "end": 1596.68, "word": " مصاب", "probability": 0.9757486979166666}, {"start": 1596.68, "end": 1597.48, "word": " بالكهابات", "probability": 0.7173828125}, {"start": 1597.48, "end": 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"probability": 0.892578125}, {"start": 1607.05, "end": 1607.63, "word": " ناكل", "probability": 0.9090169270833334}, {"start": 1607.63, "end": 1607.85, "word": " من", "probability": 0.986328125}, {"start": 1607.85, "end": 1608.31, "word": " الدم", "probability": 0.917724609375}, {"start": 1608.31, "end": 1609.33, "word": " عشان", "probability": 0.93408203125}, {"start": 1609.33, "end": 1609.79, "word": " نكتشف", "probability": 0.96953125}, {"start": 1609.79, "end": 1610.01, "word": " انه", "probability": 0.64208984375}, {"start": 1610.01, "end": 1610.15, "word": " فيه", "probability": 0.681640625}, {"start": 1610.15, "end": 1610.57, "word": " antipodes", "probability": 0.4254964192708333}, {"start": 1610.57, "end": 1610.81, "word": " ولا", "probability": 0.9140625}, {"start": 1610.81, "end": 1611.15, "word": " لا", "probability": 0.68798828125}, {"start": 1611.15, "end": 1613.49, "word": " سالمونيلا", "probability": 0.5990397135416666}, {"start": 1613.49, "end": 1614.23, "word": " تفويد", "probability": 0.6290283203125}, {"start": 1614.23, "end": 1614.81, "word": " و", "probability": 0.85888671875}, {"start": 1614.81, "end": 1615.49, "word": " براتفويد", "probability": 0.7847900390625}, {"start": 1615.49, "end": 1616.49, "word": " هذه", "probability": 0.50048828125}, {"start": 1616.49, "end": 1616.69, "word": " ال", "probability": 0.86865234375}, {"start": 1616.69, "end": 1617.09, "word": " antipodes", "probability": 0.7447916666666666}, {"start": 1617.09, "end": 1617.25, "word": " ده", "probability": 0.573974609375}, {"start": 1617.25, "end": 1617.31, "word": " و", "probability": 0.29541015625}, {"start": 1617.31, "end": 1618.01, "word": " اكتشفناها", "probability": 0.9430106026785714}, {"start": 1618.01, "end": 1618.61, "word": " اسمها", "probability": 0.9611002604166666}, {"start": 1618.61, "end": 1619.17, "word": " Vidal", "probability": 0.6163330078125}, {"start": 1619.17, "end": 1619.51, "word": " test", "probability": 0.54052734375}, {"start": 1619.51, "end": 1621.19, "word": " هو", "probability": 0.429443359375}, {"start": 1621.19, "end": 1621.91, "word": " اكتشاف", "probability": 0.991015625}, {"start": 1621.91, "end": 1622.85, "word": " لسان", "probability": 0.80224609375}, {"start": 1622.85, "end": 1623.45, "word": " مضادة", "probability": 0.862060546875}, {"start": 1623.45, "end": 1623.59, "word": " من", "probability": 0.96533203125}, {"start": 1623.59, "end": 1624.03, "word": " المرضى", "probability": 0.974609375}, {"start": 1624.03, "end": 1624.27, "word": " من", "probability": 0.56787109375}, {"start": 1624.27, "end": 1625.29, "word": " المرضى", "probability": 0.986328125}, {"start": 1625.29, "end": 1625.97, "word": " ليه", "probability": 0.85888671875}, {"start": 1625.97, "end": 1626.47, "word": " لهو", "probability": 0.875244140625}, {"start": 1626.47, "end": 1626.83, "word": " هذا", "probability": 0.95654296875}], "temperature": 1.0}, {"id": 60, "seek": 165140, "start": 1627.32, "end": 1651.4, "text": "المرض تفويت او الفارع تفويت انا يعني اكتفي بهذا القدر متوقف عند اللي هو ال Vibrio cholera يعني على اساس انه ما نطول المحاضرة عن هيك ويعني متأمل من الله عز و جل انه تكونوا انتوا استفدتم من هذه المحاضرة تالتة عشرة و اللقاء في المحاضرة راضي عشرة قريبا", "tokens": [45340, 43042, 6055, 5172, 2407, 36081, 1975, 2407, 27188, 9640, 3615, 6055, 5172, 2407, 36081, 1975, 8315, 37495, 22653, 1975, 4117, 2655, 41185, 39627, 15730, 25062, 3215, 2288, 44650, 30543, 5172, 43242, 13672, 1829, 31439, 2423, 691, 897, 6584, 20961, 1663, 37495, 22653, 15844, 24525, 32277, 16472, 3224, 19446, 8717, 9566, 12610, 9673, 5016, 46958, 25720, 18871, 39896, 4117, 4032, 40228, 22653, 44650, 10721, 42213, 9154, 21984, 6225, 11622, 4032, 10874, 1211, 16472, 3224, 6055, 30544, 14407, 16472, 2655, 14407, 44713, 5172, 3215, 39237, 9154, 29538, 9673, 5016, 46958, 25720, 6055, 6027, 2655, 3660, 6225, 8592, 25720, 4032, 13672, 4587, 16606, 8978, 9673, 5016, 46958, 25720, 12602, 46958, 1829, 6225, 8592, 25720, 12174, 16572, 3555, 995], "avg_logprob": -0.19043803062194434, "compression_ratio": 1.8669527896995708, "no_speech_prob": 1.1920928955078125e-07, "words": [{"start": 1627.32, "end": 1628.38, "word": "المرض", "probability": 0.6492919921875}, {"start": 1628.38, "end": 1628.9, "word": " تفويت", "probability": 0.59381103515625}, {"start": 1628.9, "end": 1629.24, "word": " او", "probability": 0.783935546875}, {"start": 1629.24, "end": 1629.9, "word": " الفارع", "probability": 0.624755859375}, {"start": 1629.9, "end": 1630.48, "word": " تفويت", "probability": 0.9693603515625}, {"start": 1630.48, "end": 1631.56, "word": " انا", "probability": 0.907470703125}, {"start": 1631.56, "end": 1631.88, "word": " يعني", "probability": 0.6077880859375}, {"start": 1631.88, "end": 1632.32, "word": " اكتفي", "probability": 0.9117431640625}, {"start": 1632.32, "end": 1632.62, "word": " بهذا", "probability": 0.958984375}, {"start": 1632.62, "end": 1633.0, "word": " القدر", "probability": 0.9866536458333334}, {"start": 1633.0, "end": 1633.86, "word": " متوقف", "probability": 0.7496744791666666}, {"start": 1633.86, "end": 1634.18, "word": " عند", "probability": 0.56689453125}, {"start": 1634.18, "end": 1635.0, "word": " اللي", "probability": 0.873291015625}, {"start": 1635.0, "end": 1635.16, "word": " هو", "probability": 0.96728515625}, {"start": 1635.16, "end": 1635.3, "word": " ال", "probability": 0.85498046875}, {"start": 1635.3, "end": 1635.72, "word": " Vibrio", "probability": 0.6931966145833334}, {"start": 1635.72, "end": 1636.34, "word": " cholera", "probability": 0.876953125}, {"start": 1636.34, "end": 1637.72, "word": " يعني", "probability": 0.9501953125}, {"start": 1637.72, "end": 1637.92, "word": " على", "probability": 0.89013671875}, {"start": 1637.92, "end": 1638.28, "word": " اساس", "probability": 0.827880859375}, {"start": 1638.28, "end": 1638.72, "word": " انه", "probability": 0.94189453125}, {"start": 1638.72, "end": 1639.02, "word": " ما", "probability": 0.86767578125}, {"start": 1639.02, "end": 1639.54, "word": " نطول", "probability": 0.9191080729166666}, {"start": 1639.54, "end": 1640.36, "word": " المحاضرة", "probability": 0.984619140625}, {"start": 1640.36, "end": 1640.64, "word": " عن", "probability": 0.984375}, {"start": 1640.64, "end": 1641.2, "word": " هيك", "probability": 0.961181640625}, {"start": 1641.2, "end": 1642.7, "word": " ويعني", "probability": 0.92333984375}, {"start": 1642.7, "end": 1643.46, "word": " متأمل", "probability": 0.9383138020833334}, {"start": 1643.46, "end": 1643.64, "word": " من", "probability": 0.994140625}, {"start": 1643.64, "end": 1643.9, "word": " الله", "probability": 0.9482421875}, {"start": 1643.9, "end": 1644.14, "word": " عز", "probability": 0.97509765625}, {"start": 1644.14, "end": 1644.28, "word": " و", "probability": 0.55908203125}, {"start": 1644.28, "end": 1644.56, "word": " جل", "probability": 0.956787109375}, {"start": 1644.56, "end": 1645.64, "word": " انه", "probability": 0.892333984375}, {"start": 1645.64, "end": 1646.3, "word": " تكونوا", "probability": 0.9332682291666666}, {"start": 1646.3, "end": 1646.54, "word": " انتوا", "probability": 0.8860677083333334}, {"start": 1646.54, "end": 1646.98, "word": " استفدتم", "probability": 0.74700927734375}, {"start": 1646.98, "end": 1647.1, "word": " من", "probability": 0.9482421875}, {"start": 1647.1, "end": 1647.32, "word": " هذه", "probability": 0.94287109375}, {"start": 1647.32, "end": 1647.84, "word": " المحاضرة", "probability": 0.99609375}, {"start": 1647.84, "end": 1648.3, "word": " تالتة", "probability": 0.7398681640625}, {"start": 1648.3, "end": 1648.6, "word": " عشرة", "probability": 0.8722330729166666}, {"start": 1648.6, "end": 1649.12, "word": " و", "probability": 0.74365234375}, {"start": 1649.12, "end": 1649.62, "word": " اللقاء", "probability": 0.84521484375}, {"start": 1649.62, "end": 1649.74, "word": " في", "probability": 0.94970703125}, {"start": 1649.74, "end": 1650.26, "word": " المحاضرة", "probability": 0.995361328125}, {"start": 1650.26, "end": 1650.72, "word": " راضي", "probability": 0.654296875}, {"start": 1650.72, "end": 1651.06, "word": " عشرة", "probability": 0.8971354166666666}, {"start": 1651.06, "end": 1651.4, "word": " قريبا", "probability": 0.9842529296875}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1652.123, "duration_after_vad": 1621.4034687499977}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/z6wqER2KbqA.srt b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/z6wqER2KbqA.srt
new file mode 100644
index 0000000000000000000000000000000000000000..359f4290a6fbfeebcf61f41a949718d6ef637c73
--- /dev/null
+++ b/PL9fwy3NUQKwY2VeAiCJWVIF9_gd5SI9lJ/z6wqER2KbqA.srt
@@ -0,0 +1,1330 @@
+1
+00:00:00,000 --> 00:00:05,160
+بسم الله الرحمن الرحيم الحمد لله والصلاة والسلام 
+
+2
+00:00:05,160 --> 00:00:12,580
+على النبي المصطفى بناتي في قسم البصريات الطبية مساق
+
+3
+00:00:12,580 --> 00:00:17,420
+الأحياء الدقيقة السلام عليكم ورحمة الله وبركاته
+
+4
+00:00:18,000 --> 00:00:24,580
+يطيب لي اليوم أن أبدأ المحاضرة الثامنة في هذا
+
+5
+00:00:24,580 --> 00:00:29,700
+العلم وأسأل الله عز وجل أن تسلكم وأنتم قد عدتم 
+
+6
+00:00:29,700 --> 00:00:35,890
+العدة يعني وقرأتم ليه الـ quiz القادم، أنا حقيقة آخر 
+
+7
+00:00:35,890 --> 00:00:39,410
+فريحة في المحاضرة السابعة يعني كانت على عجلة
+
+8
+00:00:39,410 --> 00:00:48,030
+فوضعتها أن أعيد هذه الـ slide يعني لأنه هي مهمة يعني 
+
+9
+00:00:48,030 --> 00:00:51,970
+مصادر العدوى في المستشفى يعني اللي مننا بدخل 
+
+10
+00:00:51,970 --> 00:00:57,430
+مستشفى بيخاف كتير إن هو يحمل عدوى و .. يعني حتى 
+
+11
+00:00:57,430 --> 00:01:00,930
+تكون غير مقصودة لأنه لا يرى هذه اللي هو الحياة
+
+12
+00:01:00,930 --> 00:01:05,030
+الدقيقة ومنها الـ .. الـ covid-19 اللي هو الـ ..
+
+13
+00:01:05,030 --> 00:01:08,250
+الفيروس السائد الآن عندنا يعني لا يرى بالعين
+
+14
+00:01:08,250 --> 00:01:12,210
+المجردة الواحد يعني ممكن يسلم على واحد، ممكن واحد
+
+15
+00:01:12,210 --> 00:01:18,690
+يعني يعطيه أكل، ممكن واحد إنه يعني يكح حواليه، ممكن
+
+16
+00:01:18,690 --> 00:01:25,410
+إنّه الواحد مثلاً يعني يحك إن هو مش عارف إنه في
+
+17
+00:01:25,410 --> 00:01:30,610
+فيروس أو في بكتيريا معاه، فاحنا في المستشفيات
+
+18
+00:01:30,610 --> 00:01:33,210
+بالذات والناس اللي أنا متخافةرة عن المستشفيات
+
+19
+00:01:33,210 --> 00:01:37,870
+حابين إن احنا نحدد يعني ما هي مصادر العدوى في 
+
+20
+00:01:37,870 --> 00:01:43,080
+المستشفيات، قلنا إنّه الأول الـ cases، اعني بالـ cases
+
+21
+00:01:43,080 --> 00:01:49,860
+المرضى يعني أنت راح تزور مريض، تحتمل كتير إن هو لما 
+
+22
+00:01:49,860 --> 00:01:55,940
+يجح أو يلمس حاجة إن هو يوصلها الـ micro بالدقيقة
+
+23
+00:01:55,940 --> 00:02:02,400
+وبالتالي أهم حاجة المرضى، الـ cases يعني حالات
+
+24
+00:02:02,400 --> 00:02:08,110
+المرضى اللي راح يزور المريض لازم يكون حاضر من إنه
+
+25
+00:02:08,110 --> 00:02:12,010
+يلامسه أو من إنه يتنفس وجهه، الحاجة التانية الـ 
+
+26
+00:02:12,010 --> 00:02:19,530
+careers، الـ حاملون يعني الناس بيحمل المرض أو بيحمل
+
+27
+00:02:19,530 --> 00:02:23,130
+ميكروب لكن لا يبدو عليه يعني هو مش مبين إنّه في
+
+28
+00:02:23,130 --> 00:02:29,910
+covid مثلاً وهؤلاء كتير بيكونوا بين المرضى وبين
+
+29
+00:02:29,910 --> 00:02:33,370
+الطاقم الطبي في المستشفى، إيش الطاقم الطبي في
+
+30
+00:02:33,370 --> 00:02:39,800
+المستشفى؟ يحتوي على طبيب وعلى حكيم ومرض وعلى أخصائي
+
+31
+00:02:39,800 --> 00:02:43,640
+الأشعة اللي بعملك الأشعة وبيحتوي على اللي هو
+
+32
+00:02:43,640 --> 00:02:47,460
+أخصائي التحاليل الطبية وحتى بيحتوي على اللي هو
+
+33
+00:02:47,460 --> 00:02:53,320
+أخصائين الإسعاف والناس، عمال النضافة، عمال النضافة
+
+34
+00:02:53,320 --> 00:02:58,680
+واللي بوزفوا الأكل يعني كل هذا اسمه medical staff
+
+35
+00:02:58,680 --> 00:03:04,710
+medical staff، الطاقم الطبي العامل داخل المستشفى، هذا 
+
+36
+00:03:04,710 --> 00:03:10,170
+كله ممكن إنه ينقل المرض للإنسان، الشيء الثاني
+
+37
+00:03:10,170 --> 00:03:17,370
+الزوار، من هنا نزور مريض نجد في الغرفة تلاتين واحد 
+
+38
+00:03:17,370 --> 00:03:25,710
+وفي الممرض ستين واحد، كل واحد منهم يعني له شؤونه، كل 
+
+39
+00:03:25,710 --> 00:03:29,390
+واحد منهم بيتنفس، كل واحد منهم بياكل، كل واحد منهم
+
+40
+00:03:29,390 --> 00:03:33,290
+يضحك، كل واحد منهم يكح، كل واحد منهم ممكن يدخن،
+
+41
+00:03:33,290 --> 00:03:38,190
+احنا مش عارفين يعني هالزحمة هذه إيش فيها، فاللي 
+
+42
+00:03:38,190 --> 00:03:43,730
+بتقول إنّه اللي بتقي الزوار والمرضى يحس إن هو 
+
+43
+00:03:44,320 --> 00:03:49,300
+يزوروا بيطلع بدون إنّه يلامس المرضى، hospital
+
+44
+00:03:49,300 --> 00:03:53,880
+visitors اللي هم الزوار، كتير الناس بيجاملوا المريض 
+
+45
+00:03:53,880 --> 00:04:00,360
+مسكين في الغرفة أهله وجرايبه وجيرانه وأصدقائه و
+
+46
+00:04:00,360 --> 00:04:04,660
+الواحد فينا بيروح يزور المريض هذا ولهو طالع مريض
+
+47
+00:04:04,660 --> 00:04:08,480
+زيه، hospital visitors يعني الزوار تلاتة
+
+48
+00:04:08,480 --> 00:04:15,190
+contaminated food الطعام الملوث، يعني كيف طعم ملوث و
+
+49
+00:04:15,190 --> 00:04:19,710
+معه المية ومعه الحليب ومعه العصير، تروح مثلاً لما 
+
+50
+00:04:19,710 --> 00:04:26,800
+تزور المريض بصوبلك إيش، بصوبلك إيش كاسة عصير تشربها 
+
+51
+00:04:26,800 --> 00:04:30,040
+أنت مش عارفها، داخل العصير إيش فيها أساسًا لإن هي في
+
+52
+00:04:30,040 --> 00:04:33,640
+المستشفى، ممكن مسكها واحد قبلك، ممكن يجلط على الأرض
+
+53
+00:04:33,640 --> 00:04:38,060
+ممكن واحد فيها شرب قبلك غسلوها وكذلك زجاجة المية
+
+54
+00:04:38,060 --> 00:04:43,860
+بتشرب منها أو عصير أو حليب اللي هو ممكن إنه داخل
+
+55
+00:04:43,860 --> 00:04:48,880
+المستشفى أي نوع من الطعام أو الشراب يكون ملوث بالـ
+
+56
+00:04:48,880 --> 00:04:51,840
+microbe اللي هو monocrobe يعني سواء بيروس أو 
+
+57
+00:04:51,840 --> 00:04:56,140
+بكتيريا، الحاجة الرابعة لمصاد العدوى في المستشفى
+
+58
+00:04:56,140 --> 00:05:00,960
+اللي هو apparatus يعني الأجهزة الطبية والـ 
+
+59
+00:05:00,960 --> 00:05:04,640
+instruments الأدوات الجراحية which are not
+
+60
+00:05:04,640 --> 00:05:10,960
+properly sterilized، التي لم يسبق يعني أن تعقم
+
+61
+00:05:10,960 --> 00:05:17,320
+يعني مثلاً واحد بدخل ليعمل عملية زائدة، عملية زائدة
+
+62
+00:05:17,320 --> 00:05:22,810
+عملية صغيرة يعني، طيب بعد يومين تلاتة التهاب الجرح
+
+63
+00:05:22,810 --> 00:05:29,010
+صار يجيب صديق وسخن وأرس على عملية إزايدة ليش؟ 
+
+64
+00:05:29,010 --> 00:05:33,850
+لأنه العملية لم تكن sterilized operation، ما كانش
+
+65
+00:05:33,850 --> 00:05:39,750
+عملية يعني معقمة، الأدوات الجراحية أو قيدة الطبيب
+
+66
+00:05:39,750 --> 00:05:45,800
+أو الممرضين ما كانش معقمة كما يجب، لذلك يعني في مصدر
+
+67
+00:05:45,800 --> 00:05:51,560
+عدوى، في مصدر عدوى الجهاز قربان مابيعقمش زي الناس 
+
+68
+00:05:51,560 --> 00:05:56,260
+الحرارة نازلة الكهربا جاطعة، طلعوا الأدوات الجراحية
+
+69
+00:05:56,260 --> 00:06:01,460
+قبل وقت، فهذه مصدر للعدوى اللي هو الأدوات الجراحية
+
+70
+00:06:01,460 --> 00:06:05,840
+وحتى الأجهزة اللي في المستشفى ممكن تكون مصدر
+
+71
+00:06:05,840 --> 00:06:12,140
+العدوى، bed sheets اللي هي الشراشف، كتير احنا بنعرف 
+
+72
+00:06:12,140 --> 00:06:16,980
+إن المريض بينام على سرير والسرير فوقه شرشة والمريض 
+
+73
+00:06:16,980 --> 00:06:21,450
+بتقطب شرشة، تأتي عمال النظافة في الصباح
+
+74
+00:06:21,450 --> 00:06:26,230
+يريدون أن ينظفوا ويمسكوا الشرشف وينفذوا ويتكوا في
+
+75
+00:06:26,230 --> 00:06:32,130
+الممر أو يتكوا بين الصرايا، هذه اللي هو النفض بتاع
+
+76
+00:06:32,130 --> 00:06:37,570
+الشراشف هذا ممكن ينشر عدوى ويفلي الناس كلها 
+
+77
+00:06:37,570 --> 00:06:42,050
+الموجودة في العنبر، إن يدخل في صدرها وفي أنفها
+
+78
+00:06:42,050 --> 00:06:46,770
+وجهاز التنفسي وفي عينيها وفي أنفها اللي هو الميات
+
+79
+00:06:47,310 --> 00:06:52,390
+من اللي هو الـ microbat الدقيقة، لذلك كان الـ bitch 
+
+80
+00:06:52,390 --> 00:06:57,530
+eats هذي مهمة يعني المفروض إنه يعني لما بنعملوا 
+
+81
+00:06:57,530 --> 00:07:00,890
+نضافة، يعملوها بطريقة صحية إنهم ياخدوها في فناء 
+
+82
+00:07:00,890 --> 00:07:06,650
+بعيد تحت الشجر في شناس وهم ينظفوها وهم يعني 
+
+83
+00:07:06,650 --> 00:07:14,340
+لبسين كمامات وجوانتات وهم النظافة، ما ينظفه يعني 
+
+84
+00:07:14,340 --> 00:07:19,700
+وصف الناس بعدين يعني هذه الشراشف المفروض تغير
+
+85
+00:07:19,700 --> 00:07:24,580
+دوريًا يعني مثلاً مريض نام يوم أو يومين وراحل إن هذه
+
+86
+00:07:24,580 --> 00:07:30,040
+تتاخد على الغسيل وتيجي بدلها شراشف نظيفة وحرامات 
+
+87
+00:07:30,040 --> 00:07:35,360
+نظيفة لم يسبق أن استخدمت يعني بدون نظافة وبدون
+
+88
+00:07:35,360 --> 00:07:41,850
+تطهير، كمان من اللي هو المصادر اللي عادوا في 
+
+89
+00:07:41,850 --> 00:07:46,870
+المستشفيات airborne dust، airborne dust يعني الغبرة
+
+90
+00:07:46,870 --> 00:07:56,490
+الغبرة يعني لو مثلاً في غرف العينين كان نفسنا
+
+91
+00:07:56,490 --> 00:08:01,660
+الأرضية ممكن يطلع غبرة، والغبرة هذه فيها micro bag 
+
+92
+00:08:01,660 --> 00:08:08,580
+لو نفضنا الشرشة أه أو نفضنا الفرشات أو المخدات أه 
+
+93
+00:08:08,580 --> 00:08:13,420
+نفس الشيء في الـ dust سواء من الأرض أو من سرير
+
+94
+00:08:13,420 --> 00:08:18,580
+المريض من محتوياته ممكن يحمل عدوى للناس العاديين
+
+95
+00:08:18,580 --> 00:08:24,000
+sneezing، sneezing يعني العطاس، أنتو عارفين العطاس
+
+96
+00:08:24,000 --> 00:08:28,580
+هذا بيطلع من الجهاز التنفسي بسرعة وصوت عالي
+
+97
+00:08:28,580 --> 00:08:34,860
+sneezing العطس أه، والعطس هذا يعني ممكن يوصل الرذاذ 
+
+98
+00:08:34,860 --> 00:08:39,700
+إلى مسافة لا تقل عن 3 أو 4 أمتار قدام المريض، فإذا 
+
+99
+00:08:39,700 --> 00:08:45,300
+كان يعني هو كان مفلولظ أو كان معاه فيروس كورونا أو
+
+100
+00:08:45,300 --> 00:08:48,840
+كان معاه حتى التهابات بكتيرية في حلقه وفي أنفه
+
+101
+00:08:48,840 --> 00:08:53,800
+ممكن إنه يوزعها عن الناس، فكيف لما هذا يكون في غرف
+
+102
+00:08:53,800 --> 00:08:59,180
+عمليات ويعني بطن العيال مفتوح أو عين العيال
+
+103
+00:08:59,180 --> 00:09:03,340
+مفتوحة وواحد يعطس، لازم العطاس يكون من كمامة
+
+104
+00:09:03,340 --> 00:09:10,040
+وجانبي، جانبي يعني مش على الناس، المصدر التام في
+
+105
+00:09:10,040 --> 00:09:15,760
+المستشفيات domestic animals، domestic يعني القليف
+
+106
+00:09:15,760 --> 00:09:21,480
+كتير بنلاقي كطب وكلاب تجدى في المستشفى هذه ممكن
+
+107
+00:09:21,480 --> 00:09:27,760
+جداً لمسها إنه يؤدي إلى إن الإنسان يحمل الـ microbe 
+
+108
+00:09:27,760 --> 00:09:34,180
+خاصة الكلاب القليفة واللي هو قطط القليفة، هذه مصادر
+
+109
+00:09:34,180 --> 00:09:36,860
+العدوى في المستشفيات واحنا الآن في هذا الوقت 
+
+110
+00:09:36,860 --> 00:09:42,860
+العصيب أحوج شيء إنّه احنا نتقي يعني هذه اللي هي
+
+111
+00:09:42,860 --> 00:09:47,460
+المصادر في المستشفيات، إذا كان عزمنا على إنه احنا
+
+112
+00:09:47,460 --> 00:09:53,140
+نزور المستشفى أو حتى يعني بيدخل مريض بمرض معين بيصير
+
+113
+00:09:53,140 --> 00:09:56,740
+معاه مرضين ثلاثة أثناء وهو نايم يعني بياخد العدوى
+
+114
+00:09:56,740 --> 00:10:00,580
+لغير مرضه من جيرانه من الناس النائمين في
+
+115
+00:10:00,580 --> 00:10:05,580
+المستشفى، الآن carriers of infection، carriers يعني 
+
+116
+00:10:05,580 --> 00:10:09,460
+الحاملون للمرض، الحاملون للميكروب أقصد، الحاملون
+
+117
+00:10:09,460 --> 00:10:13,600
+للميكروب وقد لا يبدو عليها، يبقى الـ carrier هو 
+
+118
+00:10:13,600 --> 00:10:22,600
+الحامل هو نوع من الحامل، reservoir يعني زي حامل
+
+119
+00:10:22,600 --> 00:10:30,480
+احتياطي أو خزن الميكروب، وتم اكتشافه
+
+120
+00:10:32,950 --> 00:10:39,350
+وعلاجه recovery يعني شفي من المرض لكنه لا يزال 
+
+121
+00:10:39,350 --> 00:10:43,490
+يخرج الـ pathogenic organisms اللي هو أسباب المرض
+
+122
+00:10:43,490 --> 00:10:48,630
+أو الميكروبات الدقيقة، يبقى هذه يعني مشكلة إن الحامل 
+
+123
+00:10:48,630 --> 00:10:54,870
+تعالج من مرض معين وأخد علاج ولا يبدو عليه الآن أي 
+
+124
+00:10:54,870 --> 00:11:01,130
+آخر مرض لكنه لا يزال يعني بيطلع اللي هو الـ micro
+
+125
+00:11:01,130 --> 00:11:05,270
+organs اللي بتسبب المرض لغيره، عشان هيك سمي career
+
+126
+00:11:05,270 --> 00:11:13,470
+حامل، الحامل ليه الميكروب ممكن يحمله في جهاده
+
+127
+00:11:13,470 --> 00:11:18,470
+التنفسي، خاصة الأنف، يبقى الـ nose ممكن يكون فيه آلاف
+
+128
+00:11:18,470 --> 00:11:21,970
+من الميكروبات لما الواحد يعطس أو يتنفس في وجه
+
+129
+00:11:21,970 --> 00:11:26,910
+الناس ينجل لهم الموضوع هذا، throat الحلق، الحلق اللي 
+
+130
+00:11:26,910 --> 00:11:31,950
+هو يعني في آخر أنف من تحتهذا لو عقصها الناس ممكن
+
+131
+00:11:31,950 --> 00:11:36,110
+يعمل bronchitis يعني التهاب الشعبية، الشعبية الهوائي
+
+132
+00:11:36,110 --> 00:11:41,010
+ممكن جداً إن نوصلهم بكتيريا أو ويروسات واللي مشهور
+
+133
+00:11:41,010 --> 00:11:44,710
+احنا عندنا الآن الـ covid يعني اللي بتنفس في وجه
+
+134
+00:11:44,710 --> 00:11:51,030
+واحد من مسافة تقل عن مترين ممكن يعمله الكورونا، في 
+
+135
+00:11:51,030 --> 00:11:54,510
+إن يعمله الكورونا وأنا بقول إن الـ respiratory
+
+136
+00:11:54,510 --> 00:11:58,890
+carriers هدول أخطر ناس يعني بعض الأطباء بيقولوا
+
+137
+00:11:58,890 --> 00:12:03,870
+يا عم كتير في المجتمع حاملين كوفيد وهم مش مبين
+
+138
+00:12:03,870 --> 00:12:09,550
+عليهم المرض له سخن ولا مع ضيق تنفس ولا مع عراج لكن
+
+139
+00:12:09,550 --> 00:12:14,530
+خليه يتنفس على غيره من اللي مناعتهم ضعيفة من 
+
+140
+00:12:14,530 --> 00:12:18,210
+الأمراض اللي عندهم أمراض سرطانية أو أمراض مناعية أو
+
+141
+00:12:18,210 --> 00:12:22,330
+كبار السن أو الأطفال الصغار ممكن إنه جدًا إنه ينجر
+
+142
+00:12:22,330 --> 00:12:26,530
+إليهم المرض وهو carrier يعني مش مبين عليه مش كل 
+
+143
+00:12:26,530 --> 00:12:30,330
+الناس اللي حاملين الفيروس كورونا معهم مرض كورونا
+
+144
+00:12:30,330 --> 00:12:36,310
+الحامل الثاني بكون في الجهاز البولي مثلًا ميكروب
+
+145
+00:12:36,310 --> 00:12:42,010
+التيفوئيد ممكن تعيش 14 يوم في الجهاز البولي وفي كمان
+
+146
+00:12:42,010 --> 00:12:48,770
+يعني ميكروبات أخرى في الجهاز البولي لذلك يعني صرف
+
+147
+00:12:48,770 --> 00:12:55,490
+البول والبراز بطريقة صحية في السيبون أفضل كم يحدث
+
+148
+00:12:55,490 --> 00:13:00,270
+في الخلاء ويحدث في القرى أن يكون البول والبراز على
+
+149
+00:13:00,270 --> 00:13:03,990
+وجه الأرض فتأتي الذباب تحمي الميكروب وتوصفه إلى 
+
+150
+00:13:03,990 --> 00:13:10,150
+طعام وشراب اللي هو الأصحى stool carrier يعني حامل 
+
+151
+00:13:10,150 --> 00:13:16,130
+المرض أو الميكروب في برازه في جهازه الهضمي في 
+
+152
+00:13:16,130 --> 00:13:20,270
+القولون بتاعه زي الإنتاميبة هستوليتيكا الإنتاميبة المرضية
+
+153
+00:13:20,270 --> 00:13:24,650
+أو الجيارديا لامبليا اللي عند الأطفال وممكن هذه 
+
+154
+00:13:24,650 --> 00:13:31,590
+لسنين يعني واحد إنه يحمل الـ cyst هي السيست اللي
+
+155
+00:13:31,590 --> 00:13:37,090
+هي بتاعة الإنتاميبة أو حويصلات الجيارديا لسنين وهو 
+
+156
+00:13:37,090 --> 00:13:42,410
+بيطلعها هو مش حاسس بالمرض لكن أن طلعها أن وصف أكل 
+
+157
+00:13:42,410 --> 00:13:46,290
+الناس وطعام الناس يعديهم يبقى هذا carrier خطير
+
+158
+00:13:46,290 --> 00:13:52,050
+stool carrier اللي هو في البراز في skin carrier 
+
+159
+00:13:52,050 --> 00:13:56,850
+skin carrier اللي هو على جلدنا بيقول أن كثير من
+
+160
+00:13:56,850 --> 00:14:06,020
+البكتيريا والفيروسات والفطريات أه بتكون محمولة على 
+
+161
+00:14:06,020 --> 00:14:12,120
+الجلد طبعًا البكتيريا معروفة والفطريات معروفة
+
+162
+00:14:12,120 --> 00:14:22,020
+والفطريات هي نوع من اللي هو الـ microbe تختلف عن
+
+163
+00:14:22,020 --> 00:14:26,340
+البكتيريا والفيروسات
+
+164
+00:14:26,340 --> 00:14:30,980
+ممكن تكون محمولة على الجلد والإنسان مابحث فيها
+
+165
+00:14:35,020 --> 00:14:40,960
+أن كان يعني حصل إنه تلامس مع إنسان أو واحد لبس
+
+166
+00:14:40,960 --> 00:14:46,740
+يعني ملابسه فإنّه ينقلها إلى هذا السريع يبقى هذه 
+
+167
+00:14:46,740 --> 00:14:52,620
+اللي هي الحوامل أو الحاملون للميكروبات الحاملون
+
+168
+00:14:52,620 --> 00:14:56,620
+للميكروبات الآن في موضوع جديد ومهم disease
+
+169
+00:14:56,620 --> 00:15:01,540
+progress ديزيز بروسيس عملية تقدم المرض المرض يعني
+
+170
+00:15:01,540 --> 00:15:06,620
+بيمر في أطوار مش طور واحد بيمر فيه أربعة أطوار حتى 
+
+171
+00:15:06,620 --> 00:15:13,640
+يعني يبدأ وينتهي بقول المرض الـ disease طب أنا نسيت
+
+172
+00:15:13,640 --> 00:15:17,500
+أقول أن هذه الفطريات الفنجاي الفطريات 
+
+173
+00:15:19,860 --> 00:15:25,020
+الفطريات فنجاي بالعربي الفطريات تختلف عن 
+
+174
+00:15:25,020 --> 00:15:31,220
+البكتيريا وتختلف عن الفيروسات الفطرية طيب المرض 
+
+175
+00:15:31,220 --> 00:15:38,150
+هو حقيقة يعني مسارعة ما بين competition يعني هو
+
+176
+00:15:38,150 --> 00:15:44,750
+منازلة أو مسارعة بين الـ parasite والـ host إيش الـ
+
+177
+00:15:44,750 --> 00:15:48,370
+parasite الطفيلية؟ إنّه المكروب الدقيقة وبين
+
+178
+00:15:48,370 --> 00:15:53,010
+العائل أو الإنسان اللي هو دخله فيه يبقى المرض هو
+
+179
+00:15:53,010 --> 00:15:58,690
+dynamic series of events هو مسلسل من الأحداث يعبر
+
+180
+00:15:58,690 --> 00:16:04,810
+عن منازلة أو مسارعة ما بين الـ parasite اللي غذا
+
+181
+00:16:04,810 --> 00:16:11,510
+الجسم والـ host اللي المغزو بقول إنه إحنا يعني
+
+182
+00:16:11,510 --> 00:16:19,050
+ممكن لو رسمنا رسم بياني يوضح اللي هو المدة الزمنية
+
+183
+00:16:19,050 --> 00:16:27,230
+زي هيك يعني يوضح مدة زمنية مع اللي هو ظهور أعراض مع
+
+184
+00:16:27,230 --> 00:16:33,470
+ظهور أعراض يعني هنا الرأسي ظهور الأعراض وهنا المدة
+
+185
+00:16:33,470 --> 00:16:40,810
+الزمنية المدة الزمنية ممكن إنه نلاقي أربعة اللي هو 
+
+186
+00:16:40,810 --> 00:16:49,450
+faces  phases اللي هو يعني مناطق 
+
+187
+00:16:49,450 --> 00:17:00,790
+يعني للمرض أو أطوار للمرض طيب نقول من دخول الميكروب
+
+188
+00:17:00,790 --> 00:17:05,030
+لجسم الإنسان إلى انتهاء عملية المرض ممكن إنه يلاقي 
+
+189
+00:17:05,030 --> 00:17:09,230
+أربعة أطوار يبقى certain periods الفترات الأربعة
+
+190
+00:17:09,230 --> 00:17:12,930
+اللي هي ممكن نوصفها أول واحدة incubation period
+
+191
+00:17:12,930 --> 00:17:18,650
+فترة الحضانة يعني الفترة الحضانة إنّه لما الميكروب
+
+192
+00:17:18,650 --> 00:17:24,500
+يخش جسم الإنسان مش بعد ساعة الإنسان بيصير مريض يعني
+
+193
+00:17:24,500 --> 00:17:28,940
+ممكن ياخد له يوم، يومين، تلاتة، أربعة أسبوع لما 
+
+194
+00:17:28,940 --> 00:17:32,700
+يبين طب هذه الفترة التحضنية إيش بيحصل؟ يعني بيقول لك
+
+195
+00:17:32,700 --> 00:17:37,820
+الـ microbe بدخل بتعرف على جسم الإنسان على مستوى
+
+196
+00:17:37,820 --> 00:17:42,590
+المناعة، على درجة الحرارة، على مصادر التغذية وهو 
+
+197
+00:17:42,590 --> 00:17:47,430
+وين الهدف بتاعه بده يروح داخل جسم الإنسان حتى يبدأ
+
+198
+00:17:47,430 --> 00:17:52,830
+يتكاثر ويعمل مرض يبقى مش أول ما يدخش الفيروس مثلًا
+
+199
+00:17:52,830 --> 00:17:56,070
+كورونا في جسم الإنسان بعد نص ساعة أو ساعة بيصير
+
+200
+00:17:56,070 --> 00:17:59,190
+مريض لأ بده ياخد period of incubation وإحنا هنا
+
+201
+00:17:59,190 --> 00:18:03,770
+يعني كملوله فترة حاجة صحي من أسبوع إلى أسبوعين حتى
+
+202
+00:18:03,770 --> 00:18:08,670
+مرات ثلاثة سابقة لأنه مش من أول ما وصل إنه يعمله
+
+203
+00:18:08,670 --> 00:18:13,470
+مسحة يعني بلا جيب هو موجب لأ لسه الميكروب داخل
+
+204
+00:18:13,470 --> 00:18:18,730
+يتعرف وداخل يعني يجيس المناعة فبيقول لك هذه الفترة
+
+205
+00:18:18,730 --> 00:18:28,310
+الحضانة تعكس الوقت الذي يمر ما بين دخول الميكروب
+
+206
+00:18:28,310 --> 00:18:30,470
+داخل جسم الإنسان
+
+207
+00:18:33,910 --> 00:18:40,030
+لم بداية ظهور الأعراض يعني دخل اليوم بعد أسبوع ما 
+ 
+208
+00:18:40,030 --> 00:18:46,550
+يسخن أسبوع هذا سبع أيام فترة حضانة ممكن تكون أقل 
+
+209
+00:18:46,550 --> 00:18:51,280
+أو تكون أطول المهم أن فترة حضانة طالما الأعراض لم 
+
+210
+00:18:51,280 --> 00:18:57,760
+تبدأ هي فترة حضانة تمتد من ساعة الدخول إلى ساعة الـ
+
+211
+00:18:57,760 --> 00:19:02,500
+appearance of symptoms إيه الـ symptoms الأعراض 
+
+212
+00:19:02,500 --> 00:19:07,040
+appearance of symptoms بقول مثلًا مش كل microbe
+
+213
+00:19:07,040 --> 00:19:10,680
+واحد مثلًا بكتيريا الكوليرا اللي بتعمل كوليرا بتاخد
+
+214
+00:19:10,680 --> 00:19:15,420
+ثلاث أيام وهذه short يعني قصيرة
+
+215
+00:19:17,130 --> 00:19:21,850
+ممكن إنه فيروس ثاني يدير الماء اللي بيجي الأطفال و
+
+216
+00:19:21,850 --> 00:19:28,410
+بيعملهم يعني آكلة سمائية على جلد لهم ممكن ياخد تلت
+
+217
+00:19:28,410 --> 00:19:33,210
+أربع أسابيع بينما الجذام ممكن ياخد سنوات طب الـ
+
+218
+00:19:33,210 --> 00:19:40,110
+COVID-19 يعني بياخد أسبوع إلى أسبوعين اسمها
+
+219
+00:19:40,110 --> 00:19:45,000
+incubation period فترة حضانة طيب فترة الحضانة نهارها
+
+220
+00:19:45,000 --> 00:19:52,940
+فيها محددات بقول لك تعتمد على عدد اللي هو الـ microbe
+
+221
+00:19:52,940 --> 00:19:56,200
+اللي دخل كل ما كان microbe عدده أكبر كل ما كان
+
+222
+00:19:56,200 --> 00:20:01,820
+أقصر يبقى هذا تناسب عكسي اثنين virulence of 
+
+223
+00:20:01,820 --> 00:20:06,120
+invading organisms يعني الشراسة والقوة بتاعة الـ
+
+224
+00:20:06,120 --> 00:20:10,870
+microbe كل ما كان شرس كل ما كانت قصيرة الفترة وكل 
+
+225
+00:20:10,870 --> 00:20:15,490
+ما كان هو ضعيف كل ما كانت طويلة generation time
+
+226
+00:20:15,490 --> 00:20:20,150
+اللي هو سرعة التكاثر كل ما كان بتكاثر بسرعة كل ما
+
+227
+00:20:20,150 --> 00:20:26,050
+بدأ أقصر المدة occupation period وكل ما تكاثره
+
+228
+00:20:26,050 --> 00:20:30,010
+كان أبطأ يعني مثلًا الكوليرا هذه تتكاثر كثير جدًا
+
+229
+00:20:30,010 --> 00:20:34,830
+فخلال تلات أيام بتبين يعني خلال ساعات تبدأ تتكاثر
+
+230
+00:20:34,830 --> 00:20:40,390
+بالملايين بينما مثلًا البكتيريا الليبروسي هذه أو
+
+231
+00:20:40,390 --> 00:20:44,970
+حتى الـ TB الـ TB هي لأ هذه بطيئة ممكن تاخد سنوات
+
+232
+00:20:44,970 --> 00:20:48,230
+host resistance إيه في الـ host resistance اللي هو 
+
+233
+00:20:48,230 --> 00:20:52,710
+المقاومة أو المناعة مناعة اللي هو المريض اللي دخل
+
+234
+00:20:52,710 --> 00:20:57,860
+فيه كل ما كانت المناعة قوية كل ما الفترة طالت يعني 
+
+235
+00:20:57,860 --> 00:21:02,660
+ما يبينش بسرعة لأن خلايا المناعة بتاكل اللي بتلتهم
+
+236
+00:21:02,660 --> 00:21:05,700
+اللي هو الـ microbe وكل ما كان ضعيف يعني بعد 
+
+237
+00:21:05,700 --> 00:21:10,900
+السبعين وأقل من عشر سنين ده على طول بتكون سريع و
+
+238
+00:21:10,900 --> 00:21:14,220
+بتبين فيه الأعراض أسرع فهذا الـ host resistance 
+
+239
+00:21:14,220 --> 00:21:20,940
+يعني بتكون تناسب طردي يعني كل ما كانت قوية كل ما 
+
+240
+00:21:20,940 --> 00:21:26,920
+كانت الفترة الـ Incubation period كل مكان طويلة
+
+241
+00:21:26,920 --> 00:21:33,460
+والعكس هي مناعته ضعيفة بتكون قصيرة وبتظهر في 
+
+242
+00:21:33,460 --> 00:21:39,920
+أيام طيب لجيء الطور الثاني في تقدم المرض الـ 
+
+243
+00:21:39,920 --> 00:21:43,460
+Prodromal stage Prodromal مقدمة يعني Prodromal
+
+244
+00:21:43,460 --> 00:21:52,250
+يعني تلاقي المريض تعبان ممكن معاه غثيان غثيان يعني 
+
+245
+00:21:52,250 --> 00:22:00,250
+إحنا إيش بنقول عنها ميوعة نفس يعني نفسه مأنع عنده
+
+246
+00:22:00,250 --> 00:22:09,930
+يعني فش هي للأكل أه ممكن يكون عنده صداع مليز تعب
+
+247
+00:22:09,930 --> 00:22:15,430
+إجهاد في جسمه بتقوله إيش أنت بتشكي بقول لك أنا كلي
+
+248
+00:22:15,430 --> 00:22:21,310
+تعبان أنا كل مكان كسر كل بيوجعني رأسي ظهري بيوجعني 
+
+249
+00:22:21,310 --> 00:22:27,130
+لكن فيش شيء specific الأعراض هذه indefinite و
+
+250
+00:22:27,130 --> 00:22:34,110
+general symptoms indefinite يعني مش مميزة يعني
+
+251
+00:22:34,110 --> 00:22:42,390
+مثلًا باشكيش مثلًا من مغص أو تقيؤ أو يعني باشكي من
+
+252
+00:22:42,390 --> 00:22:50,630
+وجع رأس شديد أو مثلًا باشكي من شلل لأ هو باشكي من
+
+253
+00:22:50,990 --> 00:22:55,850
+الـ indefinite symptoms من أعراض غير محددة، غير 
+
+254
+00:22:55,850 --> 00:23:01,030
+مخصصة، هذه الفترة يعني إحنا نمو فيها الواحد لما 
+
+255
+00:23:01,030 --> 00:23:05,130
+بيفلوس يعني بدأت من الفلوانزا تلاقي أنفه بيهرّج أو
+
+256
+00:23:05,770 --> 00:23:10,770
+تلاقي إنه ظهره بيوجعه ورأسه بيوجعه ونفسه ينام مش 
+
+257
+00:23:10,770 --> 00:23:14,890
+عارف ينام هذه الفترة بتطلّع يومين ثلاثة وبعدين 
+
+258
+00:23:14,890 --> 00:23:21,730
+ابتدي الفترة الضخمة الفترة هذه period of acne قمة
+
+259
+00:23:21,730 --> 00:23:26,260
+المرض قمة المرض acute stage اللي هو الفترة الحادة
+
+260
+00:23:26,260 --> 00:23:30,960
+والأعراض فيها specific إيش specific يعني محددة مش 
+
+261
+00:23:30,960 --> 00:23:34,280
+زي indefinite لأ definite يعني في specific أو 
+
+262
+00:23:34,280 --> 00:23:39,980
+different symptoms و signs وعلامات يعني علامات دي 
+
+263
+00:23:39,980 --> 00:23:46,800
+سبحرارة بتجهي 40 يعني دستور الضغط بتجهي عالي هذه 
+
+264
+00:23:46,800 --> 00:23:51,900
+sign يعني علامة الـ symptom هو ما يشكو منه المريض 
+
+265
+00:23:53,330 --> 00:23:57,890
+والـ sign هو ما يكتشفه المعالج يعني المريض بيقول لك
+
+266
+00:23:57,890 --> 00:24:03,030
+أنا سخن هذا simple جثّناله
+
+267
+00:24:03,030 --> 00:24:06,110
+بالترمومتر لقيته أربعين أو تسعة وتلاتين ونص هذه
+
+268
+00:24:06,110 --> 00:24:12,130
+sign المريض بيقول لك أنا يعني رأسي بتوجعني ومش قادر
+
+269
+00:24:12,130 --> 00:24:15,370
+جثّناله الضغط لقيته مئة وأربعين على مية هذا
+
+270
+00:24:15,370 --> 00:24:22,840
+hypertension sign يبقى الأعراض هنا مخصصة والعلامات
+
+271
+00:24:22,840 --> 00:24:29,180
+واضحة في فترة الأكمل قمة المرض هتلاقي كثير من
+
+272
+00:24:29,180 --> 00:24:38,460
+العينين عنده high fever عنده chills يرجف أه والـ 
+
+273
+00:24:38,460 --> 00:24:43,820
+chills هذه تنتج عن فرق في درجات الحرارة ما بين
+
+274
+00:24:43,820 --> 00:24:51,180
+داخل جسمه وما بين المحيط في الجو عشرين لكن هو تسعة 
+
+275
+00:24:51,180 --> 00:24:58,620
+وتلاتين لما بيتكشف بصير يرجف لأنه في اختلاف market
+
+276
+00:24:58,620 --> 00:25:02,920
+difference في الـ temperature between الـ internal
+
+277
+00:25:02,920 --> 00:25:06,560
+body compartment داخل الجسم with surrounding 
+
+278
+00:25:06,560 --> 00:25:13,740
+weather والجو المحيط ويتلاقي إن جلده dry جلده dry
+
+279
+00:25:13,740 --> 00:25:19,740
+ووجهه شاحب هذا ليه؟ لأن الجسم سبحان الله لما يشوف
+
+280
+00:25:19,740 --> 00:25:25,160
+إنسان مريض كبير بيسحب الدم إلى الداخل من الـ 
+
+281
+00:25:25,160 --> 00:25:30,060
+extremities من يديه وريديه ووجهه وبديها لل
+
+282
+00:25:30,060 --> 00:25:34,740
+internal organs اللي هو الـ organs ليش الـ internal
+
+283
+00:25:34,740 --> 00:25:39,660
+organs اللي القلب و الرئتين عشان يقاوموا المرض
+
+284
+00:25:39,660 --> 00:25:46,060
+يعني فشل الرئتين و القلب و القلة معناه موت الإنسان
+
+285
+00:25:46,390 --> 00:25:50,970
+ولكن عندما يكون يديه و رجليه باردين و وجهه شاحب و
+
+286
+00:25:50,970 --> 00:25:56,890
+لا يوجد دم جليل يعني معناه أنه نقل الدم اللي في
+
+287
+00:25:56,890 --> 00:26:01,650
+خلايا المناعة إلى الـ organs الداخلية اللي يحافظ
+
+288
+00:26:01,650 --> 00:26:05,990
+على حياته ويقاوم الأمراض في داخل الجسم يبقى هنا
+
+289
+00:26:05,990 --> 00:26:13,110
+فيه سخونة شديدة فيه ركفة فيه شحوق في الوجه و فيه 
+290
+00:26:13,110 --> 00:26:20,090
+dry skin كل هذا حتى يعني يواجه المرض بكفاءة طيب
+
+291
+00:26:20,090 --> 00:26:25,170
+الطور الرابع من period of progress اللي هو الـ period
+
+292
+00:26:25,170 --> 00:26:30,350
+of decline يعني بلحظ هنا انه بعد ما وصلنا لأكم
+
+293
+00:26:30,350 --> 00:26:36,830
+يعني هنا الأكم أقيمنا بدأنا في الـ decline decline
+
+294
+00:26:36,830 --> 00:26:45,280
+يعني النزول بدأنا في النزول إذا الـ decline phase
+
+295
+00:26:45,280 --> 00:26:51,340
+انه المرحلة بتاعت الـ severity حدث المرض الشديدة من
+
+296
+00:26:51,340 --> 00:26:56,940
+الأعراض comes to some relief relief يعني هي تنزل
+
+297
+00:26:56,940 --> 00:27:04,200
+with impression of recovery اه يكون في عنده ان هو
+
+298
+00:27:04,200 --> 00:27:13,370
+خفت الحرارة والألم خفت وبدأ المريض يعني ياكل ويعني
+
+299
+00:27:13,370 --> 00:27:17,810
+نفسه أريح فبنقول impression في انطباع بالشفاء
+
+300
+00:27:17,810 --> 00:27:24,610
+العرق هنا common بيعرق كتير لأنه يعني بدأ الدم 
+
+301
+00:27:24,610 --> 00:27:30,860
+يرجع للجلب ويتوسع الهوية الدموية فيبدأ يعرق في
+
+302
+00:27:30,860 --> 00:27:35,920
+مرحلة decline decline يعني النزول تكون عالي من
+
+303
+00:27:35,920 --> 00:27:40,680
+القمة وبنزل أخر شئ اسمه فترة اللي هو نقاهة
+
+304
+00:27:40,680 --> 00:27:45,680
+convergence period of convergence هذه هنا فترة
+
+305
+00:27:45,680 --> 00:27:52,440
+النقاها حيث تختفي الأعراض disappearance of
+
+306
+00:27:52,440 --> 00:27:56,970
+symptoms disappearance of symptoms وهي فعلا actual
+
+307
+00:27:56,970 --> 00:28:00,230
+end of disease يعني اللي له اسبوع في الـ influenza
+
+308
+00:28:00,230 --> 00:28:04,690
+الآن بدأ يقوم بدأ يعني يمشي بدأ بدأ يروح على
+
+309
+00:28:04,690 --> 00:28:10,490
+الجامعة لكن احنا لازم نؤكد على حاجة emphasize يعني
+
+310
+00:28:10,490 --> 00:28:16,550
+نؤكد على ان مناعة المريض هنا fragile fragile يعني
+
+311
+00:28:16,550 --> 00:28:20,890
+ضعيفة ممكن تنكسر يعني الـ immunity is still fragile
+
+312
+00:28:20,890 --> 00:28:27,470
+هشة هشة و ضعيفة وبالتالي مش لازم المريض يعرض حاله
+
+313
+00:28:27,470 --> 00:28:32,790
+للخطر أو للتعب الشديد لألا يدخل في فترة صعبة اسمها
+
+314
+00:28:32,790 --> 00:28:37,350
+نكسة Relapse Relapse كيف يعني؟ يعني واحد وصفوله
+
+315
+00:28:37,350 --> 00:28:43,930
+علاج التهاب صدره مدة عشر أيام أخذ الكبسولات يومين
+
+316
+00:28:43,930 --> 00:28:48,870
+والتالت حس حاله ان هو في convalescence راح رمى
+
+317
+00:28:48,870 --> 00:28:51,990
+العلاج أما بتقوله يا ابني كمل اياه، انت بتقول لا
+
+318
+00:28:51,990 --> 00:28:55,350
+أنا ثبت أنا خلاص أنا مافيش فيه حاجة، وراه الشاب
+
+319
+00:28:55,350 --> 00:29:01,310
+نزل مع أصحابه وراح على البحر وكده، بعد يوم رجع
+
+320
+00:29:01,310 --> 00:29:04,830
+أصعب من أول، و الحرارة أصعب من أول، هاد احنا بنقول
+
+321
+00:29:04,830 --> 00:29:09,640
+عنه relapse relapse ليه؟ لأنه استكتر انه خش في
+
+322
+00:29:09,640 --> 00:29:15,480
+النقاها وبحساب انه قوي، لأ منعته لسه fragile فمش
+
+323
+00:29:15,480 --> 00:29:20,220
+لازم يعرض حاله للأخطار في هذه الفترة، هذه حقيقة
+
+324
+00:29:20,220 --> 00:29:25,530
+المنحنة أنا جبته من الانترنت يعني يوضح كيف الـ
+
+325
+00:29:25,530 --> 00:29:30,950
+incubation period هذه تشفيها أعراض وبعدين بيفدأ
+
+326
+00:29:30,950 --> 00:29:36,290
+الأعراض اللي هو تطلع بالتدريج إلى أن تصل الأكم
+
+327
+00:29:36,290 --> 00:29:41,250
+الأكم هيمتد يوم يومين تلاتة ومع العلاج بيفدأ ينزل
+
+328
+00:29:41,250 --> 00:29:46,030
+بالتدريج decline إلى أن نصل اللي هو الفترة هذه
+
+329
+00:29:46,030 --> 00:29:49,630
+ممكن نقول convalescence الفترة هذه convalescence
+
+330
+00:29:49,630 --> 00:29:55,420
+أنا بشكركم طبعا كتير على يعني حسن الاجتماع وأدعوكم
+
+331
+00:29:55,420 --> 00:29:59,780
+إلى المتابعة والمراجعة وإن شاء الله هذه المحاضرة
+
+332
+00:29:59,780 --> 00:30:04,000
+تصل لكم قريبا عن طريق اللي هو الكلية إن شاء الله
+
+333
+00:30:04,000 --> 00:30:08,160
+وأنا بشكركم والسلام عليكم ورحمة الله
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/-1r5WwuGBZ4_raw.json b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/-1r5WwuGBZ4_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..82f15c7a52df6890585f61643a559b6545cdf93f
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/-1r5WwuGBZ4_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 2546, "start": 1.6, "end": 25.46, "text": "بسم الله الرحمن الرحيم والصلاة والسلام على أشرف المرسلين سيدنا محمد الصادق الأمين أما بعد استكمال اللي ما بدأنا فيه في المحاضرة السابقة حول الـSpermatogenesis و الـOogenesis تحدثنا أن كلا العمليتين تتشابه في نقطة وتختلف في ثلاث نقط تتشابه في الـPrimordial أو الـEmpirionic Germ Cell", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 16070, 9381, 15040, 3660, 16070, 3794, 37440, 15844, 5551, 8592, 28480, 9673, 2288, 3794, 1211, 9957, 8608, 25708, 8315, 3714, 35571, 3215, 31767, 18513, 4587, 16247, 2304, 9957, 5551, 15042, 39182, 44713, 24793, 6027, 13672, 1829, 19446, 47525, 10721, 8315, 8978, 3224, 8978, 9673, 5016, 46958, 25720, 21136, 16758, 28671, 11331, 12610, 2423, 39184, 50, 610, 15677, 8799, 9374, 4032, 2423, 39184, 46, 8799, 9374, 6055, 24401, 12984, 8315, 14739, 9122, 15040, 18863, 42213, 36081, 9957, 6055, 2655, 8592, 16758, 3224, 8978, 8717, 47432, 3660, 34683, 46456, 46538, 8978, 38637, 1211, 5718, 104, 8717, 47432, 6055, 2655, 8592, 16758, 3224, 8978, 2423, 39184, 47, 5565, 765, 831, 34051, 2423, 39184, 36, 2455, 347, 313, 299, 3848, 28859], "avg_logprob": -0.14283956904110945, "compression_ratio": 1.7660377358490567, "no_speech_prob": 2.562999725341797e-06, "words": [{"start": 1.6, "end": 1.92, "word": "بسم", "probability": 0.806640625}, {"start": 1.92, "end": 2.2, "word": " الله", "probability": 0.95361328125}, {"start": 2.2, "end": 2.7, "word": " الرحمن", "probability": 0.9659830729166666}, {"start": 2.7, "end": 3.22, "word": " الرحيم", "probability": 0.99365234375}, {"start": 3.22, "end": 3.76, "word": " والصلاة", "probability": 0.88232421875}, {"start": 3.76, "end": 4.34, "word": " والسلام", "probability": 0.92138671875}, {"start": 4.34, "end": 4.68, "word": " على", "probability": 0.55322265625}, {"start": 4.68, "end": 5.16, "word": " أشرف", "probability": 0.9861653645833334}, {"start": 5.16, "end": 5.82, "word": " المرسلين", "probability": 0.98623046875}, {"start": 5.82, "end": 6.32, "word": " سيدنا", "probability": 0.9095052083333334}, {"start": 6.32, "end": 6.98, "word": " محمد", "probability": 0.9676106770833334}, {"start": 6.98, "end": 7.62, "word": " الصادق", "probability": 0.984375}, {"start": 7.62, "end": 8.1, "word": " الأمين", "probability": 0.94384765625}, {"start": 8.1, "end": 8.44, "word": " أما", "probability": 0.816162109375}, {"start": 8.44, "end": 8.82, "word": " بعد", "probability": 0.9697265625}, {"start": 8.82, "end": 10.44, "word": " استكمال", "probability": 0.9674479166666666}, {"start": 10.44, "end": 10.58, "word": " اللي", "probability": 0.946044921875}, {"start": 10.58, "end": 10.76, "word": " ما", "probability": 0.76904296875}, {"start": 10.76, "end": 11.18, "word": " بدأنا", "probability": 0.9913736979166666}, {"start": 11.18, "end": 11.5, "word": " فيه", "probability": 0.97509765625}, {"start": 11.5, "end": 11.62, "word": " في", "probability": 0.96826171875}, {"start": 11.62, "end": 12.12, "word": " المحاضرة", "probability": 0.970947265625}, {"start": 12.12, "end": 12.74, "word": " السابقة", "probability": 0.9912109375}, {"start": 12.74, "end": 13.26, "word": " حول", "probability": 0.973388671875}, {"start": 13.26, "end": 14.44, "word": " الـSpermatogenesis", "probability": 0.7248883928571429}, {"start": 14.44, "end": 14.58, "word": " و", "probability": 0.74365234375}, {"start": 14.58, "end": 15.8, "word": " الـOogenesis", "probability": 0.708740234375}, {"start": 15.8, "end": 17.08, "word": " تحدثنا", "probability": 0.8626708984375}, {"start": 17.08, "end": 17.32, "word": " أن", "probability": 0.86083984375}, {"start": 17.32, "end": 17.58, "word": " كلا", "probability": 0.81298828125}, {"start": 17.58, "end": 18.44, "word": " العمليتين", "probability": 0.8807373046875}, {"start": 18.44, "end": 19.2, "word": " تتشابه", "probability": 0.98759765625}, {"start": 19.2, "end": 19.44, "word": " في", "probability": 0.97705078125}, {"start": 19.44, "end": 19.82, "word": " نقطة", "probability": 0.98095703125}, {"start": 19.82, "end": 20.4, "word": " وتختلف", "probability": 0.8330078125}, {"start": 20.4, "end": 20.58, "word": " في", "probability": 0.7998046875}, {"start": 20.58, "end": 20.9, "word": " ثلاث", "probability": 0.8258056640625}, {"start": 20.9, "end": 21.34, "word": " نقط", "probability": 0.839111328125}, {"start": 21.34, "end": 22.58, "word": " تتشابه", "probability": 0.90751953125}, {"start": 22.58, "end": 22.7, "word": " في", "probability": 0.9404296875}, {"start": 22.7, "end": 23.46, "word": " الـPrimordial", "probability": 0.8402506510416666}, {"start": 23.46, "end": 23.66, "word": " أو", "probability": 0.9228515625}, {"start": 23.66, "end": 24.66, "word": " الـEmpirionic", "probability": 0.7323172433035714}, {"start": 24.66, "end": 25.08, "word": " Germ", "probability": 0.79150390625}, {"start": 25.08, "end": 25.46, "word": " Cell", "probability": 0.88916015625}], "temperature": 1.0}, {"id": 2, "seek": 4823, "start": 26.19, "end": 48.23, "text": "وتختلف في انقسام الميتوزي وانقسام الميوزي و ال functional and structural maturation of oocyte and sperm ثم تطرقنا إلى ال oocyte بشكلها الكامل وتحدثنا أن ال oocyte تبقى في مرحلة مبكرة جدا تحت مسمى oogonium", "tokens": [35473, 46456, 46538, 8978, 16472, 4587, 3794, 10943, 9673, 36081, 2407, 11622, 1829, 4032, 7649, 4587, 3794, 10943, 9673, 1829, 2407, 11622, 1829, 4032, 2423, 11745, 293, 15067, 3803, 8167, 295, 277, 31078, 975, 293, 32899, 38637, 2304, 6055, 9566, 2288, 4587, 8315, 30731, 2423, 277, 31078, 975, 4724, 8592, 28820, 11296, 33251, 10943, 1211, 34683, 24401, 12984, 8315, 14739, 2423, 277, 31078, 975, 6055, 3555, 4587, 7578, 8978, 3714, 2288, 5016, 37977, 3714, 3555, 4117, 25720, 10874, 28259, 6055, 33753, 3714, 38251, 7578, 277, 664, 266, 2197], "avg_logprob": -0.18785112493493583, "compression_ratio": 1.5803108808290156, "no_speech_prob": 3.5762786865234375e-07, "words": [{"start": 26.19, "end": 26.89, "word": "وتختلف", "probability": 0.9156901041666666}, {"start": 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oocyte", "probability": 0.8331705729166666}, {"start": 34.19, "end": 34.37, "word": " and", "probability": 0.85595703125}, {"start": 34.37, "end": 34.79, "word": " sperm", "probability": 0.340087890625}, {"start": 34.79, "end": 36.17, "word": " ثم", "probability": 0.941162109375}, {"start": 36.17, "end": 36.97, "word": " تطرقنا", "probability": 0.922265625}, {"start": 36.97, "end": 37.29, "word": " إلى", "probability": 0.7626953125}, {"start": 37.29, "end": 37.61, "word": " ال", "probability": 0.87353515625}, {"start": 37.61, "end": 38.17, "word": " oocyte", "probability": 0.84130859375}, {"start": 38.17, "end": 38.69, "word": " بشكلها", "probability": 0.990234375}, {"start": 38.69, "end": 39.37, "word": " الكامل", "probability": 0.9695638020833334}, {"start": 39.37, "end": 40.67, "word": " وتحدثنا", "probability": 0.8756103515625}, {"start": 40.67, "end": 40.89, "word": " أن", "probability": 0.74609375}, {"start": 40.89, "end": 41.03, "word": " ال", "probability": 0.892578125}, 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"probability": 0.982421875}, {"start": 478.89, "end": 479.41, "word": " و150", "probability": 0.758544921875}, {"start": 479.41, "end": 479.89, "word": " مليون", "probability": 0.9910481770833334}, {"start": 479.89, "end": 480.27, "word": " و20", "probability": 0.893310546875}, {"start": 480.27, "end": 480.69, "word": " مليون", "probability": 0.994140625}, {"start": 480.69, "end": 481.73, "word": " بيحصل", "probability": 0.82073974609375}, {"start": 481.73, "end": 481.89, "word": " على", "probability": 0.947265625}, {"start": 481.89, "end": 482.07, "word": " هذا", "probability": 0.92822265625}, {"start": 482.07, "end": 482.55, "word": " الكام", "probability": 0.712646484375}, {"start": 482.55, "end": 482.71, "word": " من", "probability": 0.9853515625}, {"start": 482.71, "end": 482.97, "word": " عدد", "probability": 0.9851888020833334}, {"start": 482.97, "end": 483.33, "word": " الحيوانات", "probability": 0.80595703125}, {"start": 483.33, "end": 483.79, "word": " المنوية", "probability": 0.877197265625}, {"start": 483.79, "end": 484.25, "word": " من", "probability": 0.97509765625}, {"start": 484.25, "end": 484.61, "word": " خلال", "probability": 0.9957682291666666}, {"start": 484.61, "end": 485.77, "word": " استمرارية", "probability": 0.9542236328125}, {"start": 485.77, "end": 486.53, "word": " انقسام", "probability": 0.9853515625}, {"start": 486.53, "end": 487.51, "word": " الخلوي", "probability": 0.92822265625}, {"start": 487.51, "end": 488.09, "word": " تحت", "probability": 0.99267578125}, {"start": 488.09, "end": 488.63, "word": " مسمى", "probability": 0.8636067708333334}, {"start": 488.63, "end": 488.73, "word": " الـ", "probability": 0.69091796875}, {"start": 488.73, "end": 489.09, "word": " meiotic", "probability": 0.7193196614583334}, {"start": 489.09, "end": 489.47, "word": " division", "probability": 0.95654296875}], "temperature": 1.0}, {"id": 19, "seek": 51472, "start": 490.86, "end": 514.72, "text": "طيب الـ spermatogonium تدخل في مرحلة انقسام الميوزي الأول على شكل primary spermatocyte they spent several weeks passing through the first mitotic division يعني في عندي spermatogonium خضعت لانقسام الميتوزي بشكل كبير جدا", "tokens": [9566, 1829, 3555, 2423, 39184, 24152, 15677, 664, 266, 2197, 6055, 3215, 9778, 1211, 8978, 3714, 2288, 5016, 37977, 16472, 4587, 3794, 10943, 9673, 1829, 2407, 11622, 1829, 16247, 12610, 15844, 13412, 28820, 6194, 24152, 15677, 31078, 975, 436, 4418, 2940, 3259, 8437, 807, 264, 700, 2194, 9411, 10044, 37495, 22653, 8978, 18871, 16254, 24152, 15677, 664, 266, 2197, 16490, 11242, 34268, 5296, 7649, 4587, 3794, 10943, 9673, 36081, 2407, 11622, 1829, 4724, 8592, 28820, 9122, 3555, 13546, 10874, 28259], "avg_logprob": -0.18229166666666666, "compression_ratio": 1.4514563106796117, "no_speech_prob": 0.0, "words": [{"start": 490.86, "end": 491.34, "word": "طيب", "probability": 0.7920735677083334}, {"start": 491.34, "end": 491.58, "word": " الـ", "probability": 0.592041015625}, {"start": 491.58, "end": 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spent", "probability": 0.58203125}, {"start": 499.6, "end": 500.16, "word": " several", "probability": 0.92333984375}, {"start": 500.16, "end": 504.06, "word": " weeks", "probability": 0.63330078125}, {"start": 504.06, "end": 505.48, "word": " passing", "probability": 0.5849609375}, {"start": 505.48, "end": 506.18, "word": " through", "probability": 0.81884765625}, {"start": 506.18, "end": 506.4, "word": " the", "probability": 0.89794921875}, {"start": 506.4, "end": 506.76, "word": " first", "probability": 0.72021484375}, {"start": 506.76, "end": 507.14, "word": " mitotic", "probability": 0.721923828125}, {"start": 507.14, "end": 507.62, "word": " division", "probability": 0.92333984375}, {"start": 507.62, "end": 508.98, "word": " يعني", "probability": 0.83642578125}, {"start": 508.98, "end": 509.16, "word": " في", "probability": 0.76953125}, {"start": 509.16, "end": 509.46, "word": " عندي", "probability": 0.643310546875}, {"start": 509.46, "end": 510.42, "word": " spermatogonium", 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تستهلك", "probability": 0.9796142578125}, {"start": 526.42, "end": 526.72, "word": " وقت", "probability": 0.9833984375}, {"start": 526.72, "end": 527.04, "word": " كبير", "probability": 0.9934895833333334}, {"start": 527.04, "end": 527.3, "word": " جدا", "probability": 0.936767578125}, {"start": 527.3, "end": 527.44, "word": " في", "probability": 0.556640625}, {"start": 527.44, "end": 527.88, "word": " انقسام", "probability": 0.98046875}, {"start": 527.88, "end": 528.5, "word": " الميتوزي", "probability": 0.95009765625}, {"start": 528.5, "end": 528.88, "word": " الأول", "probability": 0.92724609375}, {"start": 528.88, "end": 529.56, "word": " الميوزي", "probability": 0.872509765625}, {"start": 529.56, "end": 529.88, "word": " الأول", "probability": 0.9814453125}, {"start": 529.88, "end": 530.66, "word": " قد", "probability": 0.87109375}, {"start": 530.66, "end": 530.96, "word": " يصل", "probability": 0.991943359375}, {"start": 530.96, "end": 531.26, "word": " إلى", "probability": 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خلينا نسميها", "tokens": [18954, 3175, 28868, 3714, 20292, 11536, 37893, 6806, 35525, 19452, 4724, 39648, 1804, 3175, 29538, 2423, 3678, 4724, 1829, 3555, 9957, 32239, 3224, 3714, 23557, 5016, 1211, 6055, 9566, 13063, 2423, 24152, 15677, 664, 266, 2197, 8978, 43242, 29739, 28259, 10632, 24152, 15677, 664, 266, 2197, 12595, 24152, 15677, 31078, 975, 1150, 260, 24152, 15677, 31078, 975, 24152, 15677, 327, 1017, 24152, 15677, 15151, 4106, 11933, 15730, 16247, 12610, 7578, 24152, 15677, 664, 266, 2197, 4032, 39896, 33962, 1211, 10632, 16247, 2304, 16490, 1211, 9957, 995, 8717, 38251, 1829, 11296], "avg_logprob": -0.3003090521791479, "compression_ratio": 1.6179245283018868, "no_speech_prob": 0.0, "words": [{"start": 544.57, "end": 544.93, "word": "plus", "probability": 0.208740234375}, {"start": 544.93, "end": 545.49, "word": " minus", "probability": 0.3505859375}, {"start": 545.49, "end": 546.49, "word": " 74", "probability": 0.6298828125}, {"start": 546.49, "end": 547.03, "word": " 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1108.28, "end": 1108.68, "word": " egg", "probability": 0.9384765625}, {"start": 1108.68, "end": 1111.78, "word": " لازم", "probability": 0.9938151041666666}, {"start": 1111.78, "end": 1112.62, "word": " تكون", "probability": 0.977783203125}, {"start": 1112.62, "end": 1113.2, "word": " مرتبطة", "probability": 0.96552734375}, {"start": 1113.2, "end": 1113.5, "word": " بشيء", "probability": 0.8656005859375}, {"start": 1113.5, "end": 1113.9, "word": " معين", "probability": 0.991943359375}, {"start": 1113.9, "end": 1114.18, "word": " وهو", "probability": 0.7408447265625}, {"start": 1114.18, "end": 1114.6, "word": " مستوى", "probability": 0.964111328125}, {"start": 1114.6, "end": 1114.68, "word": " ال", "probability": 0.89501953125}, {"start": 1114.68, "end": 1114.92, "word": " hormone", "probability": 0.21533203125}, {"start": 1114.92, "end": 1115.9, "word": " كمية", "probability": 0.94091796875}, {"start": 1115.9, "end": 1116.32, "word": " المادة", "probability": 0.9689127604166666}, 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بسميه follicle ال follicle هو عبارة عن سائل يحيط به cell membrane يحيط به خلايا تجريبا ان ال human ovary حوالي 120 يوم تحتاج من ال primary follicle علشان تصل إلى مرحلة ال secondary follicle", "tokens": [4117, 3215, 3224, 1975, 8315, 4724, 39648, 16472, 29739, 45865, 11242, 3660, 19446, 39894, 9566, 1211, 3615, 5296, 5016, 6027, 11296, 35525, 19452, 6055, 9566, 1211, 3615, 44650, 5016, 2407, 36520, 3660, 11778, 47283, 1211, 32771, 15040, 5172, 4724, 38251, 1829, 3224, 25483, 3520, 2423, 25483, 3520, 31439, 6225, 3555, 9640, 3660, 18871, 8608, 16373, 1211, 7251, 5016, 1829, 9566, 39627, 2815, 19651, 7251, 5016, 1829, 9566, 39627, 16490, 15040, 25528, 6055, 7435, 16572, 3555, 995, 16472, 2423, 1952, 14187, 822, 11331, 2407, 6027, 1829, 10411, 7251, 20498, 6055, 33753, 26108, 9154, 2423, 6194, 25483, 3520, 11203, 8592, 7649, 6055, 36520, 30731, 3714, 2288, 5016, 37977, 2423, 11396, 25483, 3520], "avg_logprob": -0.1815878418651787, "compression_ratio": 1.628099173553719, "no_speech_prob": 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2054.37, "word": " أو", "probability": 0.84814453125}, {"start": 2054.37, "end": 2054.53, "word": " ال", "probability": 0.98193359375}, {"start": 2054.53, "end": 2055.17, "word": " oogenesis", "probability": 0.7862955729166666}, {"start": 2055.17, "end": 2055.73, "word": " process", "probability": 0.94091796875}, {"start": 2055.73, "end": 2056.19, "word": " في", "probability": 0.93505859375}, {"start": 2056.19, "end": 2056.87, "word": " المحاضرة", "probability": 0.9947509765625}, {"start": 2056.87, "end": 2057.89, "word": " القادمة", "probability": 0.990234375}, {"start": 2057.89, "end": 2058.45, "word": " ان", "probability": 0.4814453125}, {"start": 2058.45, "end": 2058.67, "word": " شاء", "probability": 0.970458984375}, {"start": 2058.67, "end": 2058.83, "word": " الله", "probability": 0.95458984375}, {"start": 2058.83, "end": 2059.55, "word": " دمتم", "probability": 0.6756184895833334}, {"start": 2059.55, "end": 2059.73, "word": " في", "probability": 0.97265625}, {"start": 2059.73, "end": 2060.07, "word": " حفظ", "probability": 0.9972330729166666}, {"start": 2060.07, "end": 2060.33, "word": " الله", "probability": 0.935546875}, {"start": 2060.33, "end": 2060.67, "word": " و", "probability": 0.9912109375}, {"start": 2060.67, "end": 2061.33, "word": " رعايتك", "probability": 0.87294921875}], "temperature": 1.0}, {"id": 76, "seek": 206644, "start": 2061.53, "end": 2066.45, "text": "على أمل أن أرتح في الأسبوع القادم بأمر الله", "tokens": [3615, 23942, 5551, 42213, 14739, 5551, 43500, 5016, 8978, 16247, 35457, 45367, 25062, 18513, 2304, 4724, 10721, 29973, 21984], "avg_logprob": -0.15087890401482582, "compression_ratio": 1.0985915492957747, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 2061.53, "end": 2061.83, "word": "على", "probability": 0.883056640625}, {"start": 2061.83, "end": 2062.09, "word": " أمل", "probability": 0.839111328125}, {"start": 2062.09, "end": 2062.35, "word": " أن", "probability": 0.83251953125}, {"start": 2062.35, "end": 2062.77, "word": " أرتح", "probability": 0.64404296875}, {"start": 2062.77, "end": 2063.55, "word": " في", "probability": 0.73193359375}, {"start": 2063.55, "end": 2064.73, "word": " الأسبوع", "probability": 0.9440104166666666}, {"start": 2064.73, "end": 2065.55, "word": " القادم", "probability": 0.990234375}, {"start": 2065.55, "end": 2066.27, "word": " بأمر", "probability": 0.9596354166666666}, {"start": 2066.27, "end": 2066.45, "word": " الله", "probability": 0.91796875}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2105.9105625, "duration_after_vad": 2033.2837499999935}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/-1r5WwuGBZ4_raw.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/-1r5WwuGBZ4_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..dda158f78cfce1c05a6ae23e9bfbc3d8adb939ac
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/-1r5WwuGBZ4_raw.srt
@@ -0,0 +1,1860 @@
+1
+00:00:01,600 --> 00:00:05,160
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,160 --> 00:00:10,440
+المرسلين سيدنا محمد الصادق الأمين أما بعد استكمال
+
+3
+00:00:10,440 --> 00:00:13,260
+اللي ما بدأنا فيه في المحاضرة السابقة حول
+
+4
+00:00:13,260 --> 00:00:17,580
+الـSpermatogenesis و الـOogenesis تحدثنا أن كلا
+
+5
+00:00:17,580 --> 00:00:22,580
+العمليتين تتشابه في نقطة وتختلف في ثلاث نقط تتشابه
+
+6
+00:00:22,580 --> 00:00:26,890
+في الـPrimordial أو الـEmpirionic Germ Cellوتختلف
+
+7
+00:00:26,890 --> 00:00:31,210
+في انقسام الميتوزي وانقسام الميوزي و ال functional
+
+8
+00:00:31,210 --> 00:00:36,170
+and structural maturation of oocyte and sperm ثم
+
+9
+00:00:36,170 --> 00:00:41,030
+تطرقنا إلى ال oocyte بشكلها الكامل وتحدثنا أن ال
+
+10
+00:00:41,030 --> 00:00:48,230
+oocyte تبقى في مرحلة مبكرة جدا تحت مسمى oogonium
+
+11
+00:00:50,720 --> 00:00:55,820
+ثم تدخل في انقسام الميتوزي بشكل كامل لمرات متعددة
+
+12
+00:00:55,820 --> 00:01:00,580
+وتنهي الانقسام الميتوزي على شكل ال primary oocyte
+
+13
+00:01:00,580 --> 00:01:04,480
+ال primary oocyte تدخل في انقسام الميوزي الأول
+
+14
+00:01:04,480 --> 00:01:11,220
+وتستقر في stage بنسميه Diplotent stage تبقى في هذا
+
+15
+00:01:11,220 --> 00:01:17,820
+ال phase حتى سن البلوغ بمجرد حدوث ووصول ال female
+
+16
+00:01:17,820 --> 00:01:25,000
+إلى سن البلوغ يبدأالـ ovary كل شهر في انضاج 10 إلى
+
+17
+00:01:25,000 --> 00:01:30,460
+30 primary oocyte تستكمل انقسم الميوز الأول وتدخل
+
+18
+00:01:30,460 --> 00:01:34,320
+في انقسم الميوز التاني وتستقر وتدخل في انقسم
+
+19
+00:01:34,320 --> 00:01:39,180
+الميوز التاني تدخل في انقسم الميوز التاني على شكل
+
+20
+00:01:39,180 --> 00:01:43,440
+أيضًا زي ما شفنا في الصورة السابقة من المحاضرة
+
+21
+00:01:43,440 --> 00:01:49,990
+السابقة دخلت primary oocyte تملتالانقسام الميوزي
+
+22
+00:01:49,990 --> 00:01:53,470
+الأول اللي كان واقف في مرحلة الـdiplotent stage
+
+23
+00:01:53,470 --> 00:01:57,890
+كملت انقسام الميوزي الأول بشكله الكامل أعطتلي
+
+24
+00:01:57,890 --> 00:02:02,490
+secondary oocyte زائد first polar body ال
+
+25
+00:02:02,490 --> 00:02:07,350
+secondary oocyte تستمر في الانقسام الميوزي الثاني
+
+26
+00:02:07,350 --> 00:02:14,010
+حتى لحظة ال ovulation ولكن قبل ال ovulation بتكون
+
+27
+00:02:14,010 --> 00:02:18,070
+وكفة هذه البويضة اللي اسمة secondary oocyteفي
+
+28
+00:02:18,070 --> 00:02:23,470
+مرحلة الـ META Phase 2 طبعا هذه العملية الـ 20 أو
+
+29
+00:02:23,470 --> 00:02:27,530
+30 خلية اللي كانت على شكل الـ primary oocyte ووصلت
+
+30
+00:02:27,530 --> 00:02:31,630
+على شكل الـ 30 مشكلهم بيخضعوا لعملية الـ ovulation
+
+31
+00:02:31,630 --> 00:02:35,970
+الطويلة الطويلة تنتين، واحد، اتنين، تلاتة، وايضا
+
+32
+00:02:35,970 --> 00:02:39,810
+على الأكثر والباقى بيروح لمرحلة الاتريجيا أو
+
+33
+00:02:39,810 --> 00:02:43,570
+الأتريجيا بشكل كامل وهي عبارة عن الـ degeneration
+
+34
+00:02:43,570 --> 00:02:48,240
+of oocyteهذه العملية تستمر بهذا الشكل كل شهر لمدة
+
+35
+00:02:48,240 --> 00:02:55,400
+45 أو 50 سنة الـ secondary oocyte تبدأ في الإنقسام
+
+36
+00:02:55,400 --> 00:03:01,300
+الميتوزي لكن هذه السلسلة ستكون مقفلة في مرحلة
+
+37
+00:03:01,300 --> 00:03:05,820
+محددة تسمى Metaphyse II وهو الإنقسام الميوزي
+
+38
+00:03:05,820 --> 00:03:10,620
+التاني في مرحلة الـ Metaphyse وهي مرحلة استفاف
+
+39
+00:03:10,620 --> 00:03:16,540
+الكرمزومات في منتصف الخليةعبارة عن 2-chromosome او
+
+40
+00:03:16,540 --> 00:03:22,220
+2N استعدادا للفيرتاليزيشن ماهي اللي بيخليها تستكمل
+
+41
+00:03:22,220 --> 00:03:25,040
+اقسام الميوزي التاني هي عبارة عن عملية ال
+
+42
+00:03:25,040 --> 00:03:27,960
+fertilization the stimulation for the releasing
+
+43
+00:03:27,960 --> 00:03:31,380
+from this meiotic block is fertilization by
+
+44
+00:03:31,380 --> 00:03:34,760
+spermatozoon يعني بمجرد البويضة اللي وكفت في
+
+45
+00:03:34,760 --> 00:03:38,890
+الmetaphase 2 والتي تحتوى على 2-chromosomeومجرد
+
+46
+00:03:38,890 --> 00:03:42,470
+حدوث عملية تلقيح لها بيبدأ تشغّل على هذا البواي ده
+
+47
+00:03:42,470 --> 00:03:46,630
+عشان تستكمل تسعى الميوزي الثاني الـ Unfertilized
+
+48
+00:03:46,630 --> 00:03:51,290
+secondary oocyte will be filled or will be failure
+
+49
+00:03:51,290 --> 00:03:55,630
+to complete the secondary meiotic division ال
+
+50
+00:03:55,630 --> 00:03:58,670
+secondary meiotic division مش هتقدر تكمله فبالتالي
+
+51
+00:03:58,670 --> 00:04:04,860
+هتدخل في مرحلة الأتراجيا أو تنزل مع ال bleedingأو
+
+52
+00:04:04,860 --> 00:04:09,220
+مع الـ menstrual cycle على هيئة secondary oocyte
+
+53
+00:04:09,220 --> 00:04:12,200
+the first polar body may be divided during the
+
+54
+00:04:12,200 --> 00:04:16,540
+secondary mitotic division as we see in the last
+
+55
+00:04:16,540 --> 00:04:22,340
+video خلينا نشوف هذا الفيديو اللي بتكلم أيضا عن
+
+56
+00:04:22,340 --> 00:04:27,880
+عملية الـ oogenesis وكيف تتم ولكن هذا بتحدث عن ال
+
+57
+00:04:27,880 --> 00:04:32,010
+polar body بشكل عام هي في عندي primary oocyteفيها
+
+58
+00:04:32,010 --> 00:04:35,930
+احد اتنين تلاتة اربع four كرموزوم فكده بنسميها في
+
+59
+00:04:35,930 --> 00:04:39,590
+الأصل لازم تكون اتنين فكده ساموها deploy to N
+
+60
+00:04:39,590 --> 00:04:45,930
+هتدخل انقسام الميوزي الأول قسمت انقسام الميوزي
+
+61
+00:04:45,930 --> 00:04:50,330
+الأول خلصت من نصف عدد الكرموزومات أعطتني خلية
+
+62
+00:04:50,330 --> 00:04:53,570
+تحتوى على two كرموزوم وخلية تحتوى على two كرموزوم
+
+63
+00:04:53,570 --> 00:04:55,830
+هذه خلية تحتوى على كمية كافية من الـcytoplasm
+
+64
+00:04:55,830 --> 00:05:00,910
+فسماهاprimary or secondary oocyte و هذه خلية تحتوي
+
+65
+00:05:00,910 --> 00:05:05,770
+على عدد قليل جدا من عضيات وكمية صغيرة جدا من
+
+66
+00:05:05,770 --> 00:05:09,190
+الcytoplasm اللي هي تكفي الاستمرار فبسميها polar
+
+67
+00:05:09,190 --> 00:05:13,750
+body طبعا
+
+68
+00:05:13,750 --> 00:05:17,650
+هذه ال first polar body تدخل انقسم الميوزي التاني
+
+69
+00:05:17,650 --> 00:05:20,890
+علشان تجف ال meta phase بمجرد حدوث ال
+
+70
+00:05:20,890 --> 00:05:25,970
+fertilizationتبدأ بتتخلص من نصف عدد الكرمزومات
+
+71
+00:05:25,970 --> 00:05:30,890
+وتحصل على كرمزوم من الأب وكرمزوم من الأم وحصلت على
+
+72
+00:05:30,890 --> 00:05:34,310
+two polar bodies وخلّيكم فاكرين المعلومة هذه إن
+
+73
+00:05:34,310 --> 00:05:39,890
+الخلية إذا كانت mature بتكون خلية تحتوى على two
+
+74
+00:05:39,890 --> 00:05:42,890
+chromosomes for example إذا كنا بنحكي إنه عدد
+
+75
+00:05:42,890 --> 00:05:46,190
+الكرمزومات الأصلية اتنينولكن تحتوي بجوارها على
+
+76
+00:05:46,190 --> 00:05:49,690
+first polar body بعد ال fertilization ما بتصير
+
+77
+00:05:49,690 --> 00:05:54,710
+first polar body في عند ال second polar body تبعد
+
+78
+00:05:54,710 --> 00:05:58,090
+الكرموزومات في الخلية قبل عملية ال fertilization
+
+79
+00:05:58,090 --> 00:06:04,490
+لازم تكون employed لازم تكون employed لمجرد حدوث
+
+80
+00:06:04,490 --> 00:06:10,270
+ال fertilization علشان تستكمل عملية التطوير هذا
+
+81
+00:06:10,270 --> 00:06:15,290
+بالنسبة إلى البوابةخلّينا نشوف استكمال هذه
+
+82
+00:06:15,290 --> 00:06:20,210
+العملية، ماذا سيحدث فيما بعد قلصنا من الـ Female
+
+83
+00:06:20,210 --> 00:06:23,550
+وماذا سيحدث مع الـ Female خلال عملية الـ Oogenesis
+
+84
+00:06:23,550 --> 00:06:27,210
+وكيف تتطور البويضات وفي أي مرحلة تجهز وفي أي stage
+
+85
+00:06:27,210 --> 00:06:32,250
+وكيف تتصير من 2C إلى 1C يعني من 2 كرمزوم إلى 1
+
+86
+00:06:32,250 --> 00:06:36,950
+كرمزوم نجي للمين، وهو القسم الميوزي للـ Female
+
+87
+00:06:36,950 --> 00:06:43,090
+القسم الميوزي للـ Femalein the male does not
+
+88
+00:06:43,090 --> 00:06:47,850
+beginning until after puberty يعني ما بيصير انقسام
+
+89
+00:06:47,850 --> 00:06:54,350
+ميوزي عند الذكور إلا بعد عملية البلوك وهذا بخلاف
+
+90
+00:06:54,350 --> 00:06:58,210
+اللي ما يحدث عند ال female بخلاف ما يحدث عند ال
+
+91
+00:06:58,210 --> 00:07:03,010
+female الشغل التاني الخلاف التاني انه مش كل ال
+
+92
+00:07:03,010 --> 00:07:06,990
+spermatogonium تخضع انقسام الميوزي وإلا ما بيصير
+
+93
+00:07:06,990 --> 00:07:10,530
+في عند استمرارية في إنتاج ال sperm وإلا كلهم خضعوا
+
+94
+00:07:10,530 --> 00:07:13,510
+انقسام الميوزيفكلهم بقى فترة زمنية بيصيرها
+
+95
+00:07:13,510 --> 00:07:17,610
+degeneration فما بيصير عندي spermato site موجودة
+
+96
+00:07:17,610 --> 00:07:20,770
+ما بيصير عندي spermato zoo موجودة فبصير عند ال
+
+97
+00:07:20,770 --> 00:07:24,970
+fertility إذا النقطتين أساسيتين النقطة الأولى إن
+
+98
+00:07:24,970 --> 00:07:29,830
+انقسام الميوزي عند الذكور ما بيبدأ إلا بعد سن
+
+99
+00:07:29,830 --> 00:07:35,230
+البلوغ انقسام الميوزي لل spermatogonia عند الذكور
+
+100
+00:07:35,230 --> 00:07:40,010
+ما بيبدأ كله مع بعض في نفس اللحظة بيبدأ على فتراتA
+
+101
+00:07:40,010 --> 00:07:43,890
+large number of spermatogonia spermatogonia remain
+
+102
+00:07:43,890 --> 00:07:48,290
+in meiotic cycle throughout much of the
+
+103
+00:07:48,290 --> 00:07:52,870
+reproductive lifetime of male يعني كله بيصير ويبقى
+
+104
+00:07:52,870 --> 00:07:55,590
+في انقسام الميوتوزي ويستمر في انقسام الميوتوزي
+
+105
+00:07:55,590 --> 00:07:59,890
+بشكل مستمر وإلا كيف بيحصل على 200 مليون و150 مليون
+
+106
+00:07:59,890 --> 00:08:03,330
+و20 مليون بيحصل على هذا الكام من عدد الحيوانات
+
+107
+00:08:03,330 --> 00:08:08,630
+المنوية من خلال استمرارية انقسام الخلوي تحت مسمى
+
+108
+00:08:08,630 --> 00:08:13,460
+الـ meiotic divisionطيب الـ spermatogonium تدخل في
+
+109
+00:08:13,460 --> 00:08:17,420
+مرحلة انقسام الميوزي الأول على شكل primary
+
+110
+00:08:17,420 --> 00:08:24,060
+spermatocyte they spent several weeks
+
+111
+00:08:24,060 --> 00:08:29,160
+passing through the first mitotic division يعني في
+
+112
+00:08:29,160 --> 00:08:34,060
+عندي spermatogonium خضعت لانقسام الميتوزي بشكل
+
+113
+00:08:34,060 --> 00:08:38,500
+كبير جداهتدخل الـ spermatogonium على شكل
+
+114
+00:08:38,500 --> 00:08:42,560
+spermatocyte primary spermatocyte انقسام الميتوزي
+
+115
+00:08:42,560 --> 00:08:47,880
+الميوزي الأول وتبقى تستهلك وقت كبير جدا في انقسام
+
+116
+00:08:47,880 --> 00:08:52,320
+الميتوزي الأول الميوزي الأول قد يصل إلى عدة أسابيع
+
+117
+00:08:52,320 --> 00:08:58,000
+عملية تخليق ال spermatocyte من بدايتها من منطقة ال
+
+118
+00:08:58,000 --> 00:09:03,020
+spermatogonium حتى منطقة ال mature sperm تاخد 74
+
+119
+00:09:03,020 --> 00:09:08,990
+يومplus minus 74 مليون مش fixed ولكن بقول plus
+
+120
+00:09:08,990 --> 00:09:14,050
+minus هذه ال background بيبين ليه مراحل تطور ال
+
+121
+00:09:14,050 --> 00:09:17,250
+spermatogonium في عند البداية spermatogonium
+
+122
+00:09:17,250 --> 00:09:23,030
+primer spermatocyte seconder spermatocyte
+
+123
+00:09:23,030 --> 00:09:28,190
+spermatid 4 spermatozoon إذا الأولى spermatogonium
+
+124
+00:09:28,190 --> 00:09:32,900
+و هي الخلية الأم خلينا نسميهاالـ spermatozoa أو
+
+125
+00:09:32,900 --> 00:09:38,520
+الـ sperm هي عبارة عن الـ mature sperm في مرحلة
+
+126
+00:09:38,520 --> 00:09:41,740
+بيسميها spermatogenesis و هي عبارة عن عملية
+
+127
+00:09:41,740 --> 00:09:46,500
+التخليق بشكل كام ماذا يحصل؟ في الـ spermatogonium
+
+128
+00:09:46,500 --> 00:09:51,380
+يتضاعف المادة الوراثية تتصير 4S يعني أربعة
+
+129
+00:09:51,380 --> 00:09:55,960
+كروموزوم تدخل الأقسام الميوزي الأول على شكل الـ
+
+130
+00:09:55,960 --> 00:10:00,550
+primary spermatocyteفيها أربعة كرموزومات للتقريب
+
+131
+00:10:00,550 --> 00:10:04,890
+.. للتقريب عدد الكرموزومات بيكتمل القسم الميوزي
+
+132
+00:10:04,890 --> 00:10:10,550
+الأول فكل sperm .. فكل primary spermatocyte تعطيني
+
+133
+00:10:10,550 --> 00:10:14,790
+خليتين كل خلية فيها نصف عدد الكرموزومات فالأصل كان
+
+134
+00:10:14,790 --> 00:10:18,990
+في عندي أربع كرموزومات هجسمهم الأتنين هتعطيني
+
+135
+00:10:18,990 --> 00:10:23,090
+خليتين كل خلية فيها اتنين كرموزومعشان كده سماها
+
+136
+00:10:23,090 --> 00:10:27,630
+secondary spermatocyte من حيث الاسم ولكن من حيث
+
+137
+00:10:27,630 --> 00:10:32,170
+شكل الـ two two secondary spermatocyte إذاً خليتين
+
+138
+00:10:32,170 --> 00:10:36,530
+اتنين في اتنين كروموزوم اربعة كروموزوماتبعد كده
+
+139
+00:10:36,530 --> 00:10:41,050
+بيستمر الانقسام الميوزي التاني فكل خلية بتعطيني
+
+140
+00:10:41,050 --> 00:10:46,690
+خليتين فتوسف secondary spermatocyte بتعطيني four
+
+141
+00:10:46,690 --> 00:10:52,710
+spermatin كل خلية فيها نصف عدد كرومزومات secondary
+
+142
+00:10:52,710 --> 00:10:56,350
+spermatin أو أفر secondary spermatocyte اللي هي
+
+143
+00:10:56,350 --> 00:11:00,230
+عبارة عن اتنين كرومزوم يعني فيها one كرومزوم بعدين
+
+144
+00:11:00,230 --> 00:11:05,830
+تبدأ عملية ال maturation عشان نحصل علىSpermatozoa
+
+145
+00:11:05,830 --> 00:11:09,150
+عملية الـ maturation بتاخد لها من أسبوعين لثلاث
+
+146
+00:11:09,150 --> 00:11:12,990
+أسابيع إذا ال spermatogonium عشان يصير DNA
+
+147
+00:11:12,990 --> 00:11:17,810
+replication بتاخد لها 16 يوم ك duration ال primary
+
+148
+00:11:17,810 --> 00:11:21,630
+spermatocyte عشان تخلص انقسام الميوزي الأول بتاخد
+
+149
+00:11:21,630 --> 00:11:26,850
+لها 24 يوم maximum 30 secondary spermatocyte عشان
+
+150
+00:11:26,850 --> 00:11:32,180
+تخلص انقسام الميوزي التاني بتاخد لها يوم كاملالـ
+
+151
+00:11:32,180 --> 00:11:35,720
+spermatease عشان تتطور و تعطيني immature haploid
+
+152
+00:11:35,720 --> 00:11:41,380
+جميد تعطيني تقريبا اربعة و سبعة و عشرين يوم سبعة و
+
+153
+00:11:41,380 --> 00:11:45,480
+عشرين يوم و يوم تمانية و عشرين تمانية و عشرين و
+
+154
+00:11:45,480 --> 00:11:51,660
+اربعة و عشرين جول تلاتين تلاتين اتنين و خمسين و
+
+155
+00:11:51,660 --> 00:11:57,670
+ستة تمانية و خمسينعشرة تمانية و سبتين تمانية و
+
+156
+00:11:57,670 --> 00:12:02,470
+سبتين plus minus لو زودت للتلاتين او للتمنبعش
+
+157
+00:12:02,470 --> 00:12:08,190
+هتلاقي اربعة و سبعين يوم زاد minus زاد ناقص اكتر
+
+158
+00:12:08,190 --> 00:12:12,670
+من يوم عملية ال maturation لل spermatin وتحويلها
+
+159
+00:12:12,670 --> 00:12:16,650
+إلى ال spermatozoa او ال sperm تاخدلها اسبوعين
+
+160
+00:12:16,650 --> 00:12:20,870
+تاخدلها اسبوعين تاخدلها two week
+
+161
+00:12:22,890 --> 00:12:27,370
+طبعا هذه شكل الـ Testis الخاص بالميل في منطقة
+
+162
+00:12:27,370 --> 00:12:30,450
+بنتسميها الـ Epidermis أو البربخ وهي المنطقة اللي
+
+163
+00:12:30,450 --> 00:12:33,870
+تخزن فيها الـ Sperm ال Vase Difference اللي هو
+
+164
+00:12:33,870 --> 00:12:37,670
+العقل الناقل و ال Testis اللي فيها ال semi-nervous
+
+165
+00:12:37,670 --> 00:12:43,370
+تبيول المصنع اللي بتنفيه الرصنية ال sperm لو أخدت
+
+166
+00:12:43,370 --> 00:12:46,190
+مقفلة من ال semi-nervous هلاجي في عندي خلية
+
+167
+00:12:46,190 --> 00:12:49,710
+بتسميها الـ Sertoli cell هعرف ال function الخاصة
+
+168
+00:12:49,710 --> 00:12:53,490
+بالـ Sertoli cell بشكل كاملفي المحاضرات القادمة
+
+169
+00:12:53,490 --> 00:12:58,350
+سيرتوليسيل تبدأ حواليها spermatogonia أو
+
+170
+00:12:58,350 --> 00:13:02,650
+spermatogonia تنقسم انقسام ميوزي للوصول لـ
+
+171
+00:13:02,650 --> 00:13:07,330
+spermatocyte spermatocyte بتخلص انقسام الميوزي
+
+172
+00:13:07,330 --> 00:13:11,830
+الأول عشان تعطيني seconder spermatocyte عدد اتنين
+
+173
+00:13:11,830 --> 00:13:15,250
+seconder spermatocyte عدد اتنين هتدخل في انقسام
+
+174
+00:13:15,250 --> 00:13:18,650
+الميوزي التاني هتعطيني أربع خلايا بتسميها
+
+175
+00:13:18,650 --> 00:13:22,020
+spermatitesالاربع خلايا الـ spermatite هيصلها
+
+176
+00:13:22,020 --> 00:13:26,740
+maturation وطياطيني لـ sperm أو لـ spermatozoa
+
+177
+00:13:26,740 --> 00:13:30,100
+يعني في المقالات العلمية بيسموها sperm أو بيسموها
+
+178
+00:13:30,100 --> 00:13:34,100
+mature sperm أو بيسموها spermatozoa لو أخدت ال one
+
+179
+00:13:34,100 --> 00:13:39,940
+sperm هلاجي فيه تركيبة ال head ال mid piece و ال
+
+180
+00:13:39,940 --> 00:13:43,180
+tail ال tail مهم جدا للحركة ال mid piece فيها
+
+181
+00:13:43,180 --> 00:13:47,320
+متاكندرية لإنتاج الطاقةوالـ Head فيه الـ Acrosome
+
+182
+00:13:47,320 --> 00:13:50,160
+الخاص بالـ Fertilization لأنه فيه إنزيمات تساعد
+
+183
+00:13:50,160 --> 00:13:53,460
+على اختراق البويضة سنعرف ما هو الـ Acrosome وكيف
+
+184
+00:13:53,460 --> 00:13:56,380
+تصبح الـ Lysis وماذا عن إنزيمات اللي فيه وفيه أند
+
+185
+00:13:56,380 --> 00:14:01,420
+النواء وهي المادة الوراثية الخاصة بالأب هل ال
+
+186
+00:14:01,420 --> 00:14:06,280
+sperm يحتوي على Single Metacondria لأ ال sperm
+
+187
+00:14:06,280 --> 00:14:11,410
+يحتوي على أكثر منمن خمسين لسبعين متاكندرية إذا
+
+188
+00:14:11,410 --> 00:14:15,770
+مافي عندى خلية فيها single متاكندرية زي ال sperm
+
+189
+00:14:15,770 --> 00:14:19,210
+لأ في من خمسين لسبعين وفي بعض الدراسات بتقول 100
+
+190
+00:14:19,210 --> 00:14:24,470
+متاكندرية موجودة بال sperm صورة بتوضح الفرق ما بين
+
+191
+00:14:24,470 --> 00:14:29,610
+ال oogenesis على اليمين مقارنة بال spermatogenesis
+
+192
+00:14:29,610 --> 00:14:34,640
+هنبدأ بال oogenesis هتبدأ بال Ogoniumهأمر بعد
+
+193
+00:14:34,640 --> 00:14:38,720
+انقسام الميتوزي primary oocyte هتدخل انقسام
+
+194
+00:14:38,720 --> 00:14:42,440
+الميوزي أول secondary oocyte زايد first polar body
+
+195
+00:14:42,440 --> 00:14:47,240
+انقسام الميتوزي التاني هتعطيني oocyte زايد second
+
+196
+00:14:47,240 --> 00:14:51,120
+polar body بعد ال fertilization فأخدوا فالك بعد ال
+
+197
+00:14:51,120 --> 00:14:53,720
+fertilization لازم يطلع ال secondary polar body
+
+198
+00:14:53,720 --> 00:14:58,680
+اسم ال metagonian هتدخل عملية التطوير للمادة
+
+199
+00:14:58,680 --> 00:15:02,360
+الوراثية وتضاعفها تديني primary من خلال انقسام
+
+200
+00:15:02,360 --> 00:15:05,740
+الميتوزيهتعطيني primary spermatocyte عشان كده بما
+
+201
+00:15:05,740 --> 00:15:10,000
+يقول growth و maturation معناه انقسام ميتوزي ال
+
+202
+00:15:10,000 --> 00:15:13,340
+primary و ال oocyte هتدخل انقسام ميوزي أول هتعطيني
+
+203
+00:15:13,340 --> 00:15:18,120
+secondary و secondary هتعطيني two secondary
+
+204
+00:15:18,120 --> 00:15:21,360
+spermatocyte كل واحدة منهم هتدخل انقسام ميوزي تاني
+
+205
+00:15:21,360 --> 00:15:24,080
+هتعطيني spermatite ال spermatite بسبب ال
+
+206
+00:15:24,080 --> 00:15:25,680
+maturation و ال differentiation هتعطيني
+
+207
+00:15:25,680 --> 00:15:30,540
+spermatozoa نيجي لأخر stage من مراحل ال
+
+208
+00:15:30,540 --> 00:15:33,880
+spermatogenesis و ال oogenesisوهو عبارة عن الـ
+
+209
+00:15:33,880 --> 00:15:36,740
+Final Structure and Functional Maturation of
+
+210
+00:15:36,740 --> 00:15:41,740
+Oocyte and Sperm ناخدها واحدة واحدة الـ Eugenesis
+
+211
+00:15:41,740 --> 00:15:46,940
+وهي عبارة عن عملية تخليق البويضة حوالي عدد
+
+212
+00:15:46,940 --> 00:15:52,040
+البويضات الموجودة في الـ Ovary في مرحلة جنينية
+
+213
+00:15:52,040 --> 00:15:57,620
+تقدر بـ 7 مليون بويضة ولكناللي بصل لمرحلة ال
+
+214
+00:15:57,620 --> 00:16:02,060
+primary oocyte فقط 2 مليون بوايدة يعني عندك حوالي
+
+215
+00:16:02,060 --> 00:16:07,960
+5 مليون بوايدة دخلت مرحلة ال atresia طيب لما تصير
+
+216
+00:16:07,960 --> 00:16:14,680
+ميلاد و نحصل على طفل جنسه أنثى المبيض في هذا الوقت
+
+217
+00:16:14,680 --> 00:16:22,560
+only about 600000 of oocyte هتكون arrested في
+
+218
+00:16:22,560 --> 00:16:27,740
+مرحلة الضيب latent stageمن أصل اتنين مليون يعني
+
+219
+00:16:27,740 --> 00:16:34,100
+الباقي صارله اتراجع of the first mitotic division
+
+220
+00:16:34,100 --> 00:16:38,860
+survival until puberty يعني السبعة مليون اللي
+
+221
+00:16:38,860 --> 00:16:44,440
+كانوا في المبيعات بمجرد .. بمجرد الميلاد بيصيروا
+
+222
+00:16:44,440 --> 00:16:50,520
+اتنين مليون الاتنين مليون بمجرد وصول إلى سن البلوغ
+
+223
+00:16:50,520 --> 00:16:54,400
+بيصيروا ستمائة الف بويضةمن سبعة مليون صاروا اتنين
+
+224
+00:16:54,400 --> 00:17:00,680
+مليون بعدين ست ميت .. ست ميت الف بوايدة بعد ال
+
+225
+00:17:00,680 --> 00:17:05,240
+blue و بمجرد ما تبدأ ال menstrual cycle السيدة
+
+226
+00:17:05,240 --> 00:17:09,460
+بتفقد تقريبا .. تقريبا ميت بوايدة طبعا مش ميت
+
+227
+00:17:09,460 --> 00:17:13,080
+بوايدة يروحوا مع ال pleading لأ ميت بوايدة في كل
+
+228
+00:17:13,080 --> 00:17:18,700
+دورة اترجى immature egg every month only a single
+
+229
+00:17:18,700 --> 00:17:24,960
+egg should beAt least there are exceptions which
+
+230
+00:17:24,960 --> 00:17:30,680
+in some cases lead to twins عشان هنا كده بقولك أن
+
+231
+00:17:30,680 --> 00:17:35,900
+الأنثى لما تصل لسن البلوخ هيكون فيها عندها 600 ألف
+
+232
+00:17:35,900 --> 00:17:41,900
+ويدة مستقرة في ال diaper rotten stage ومستعدة تدخل
+
+233
+00:17:41,900 --> 00:17:48,340
+متسامل الميتوزي التانيكل شهر من بعد البلوغ السيدة
+
+234
+00:17:48,340 --> 00:17:52,040
+تفقد حوالي ألف بويضة في بعضهم بيقولك 700 بويضة
+
+235
+00:17:52,040 --> 00:17:56,380
+طبعا أتريجيا فقط
+
+236
+00:17:56,380 --> 00:18:01,440
+المسموح له يصير له maturation بويضة واحدة وبعض
+
+237
+00:18:01,440 --> 00:18:05,240
+الأحيان تنتين عشان كده بنلاقي twins بعضهم بيصير
+
+238
+00:18:05,240 --> 00:18:10,120
+تلاتة حالات نادرة ال egg along with its
+
+239
+00:18:10,120 --> 00:18:13,880
+surrounding cell بنسميها follicle هل ال eggبتطلع
+
+240
+00:18:13,880 --> 00:18:18,940
+لحالها لأ ال egg بتطلع ضمن محفظات بسميها follicle
+
+241
+00:18:18,940 --> 00:18:22,780
+هنعرف إيش هي ال follicle و إيش مكونة ال follicle و
+
+242
+00:18:22,780 --> 00:18:28,680
+إيش فيها من المواد ال maturation of oocyte or egg
+
+243
+00:18:28,680 --> 00:18:31,780
+لازم
+
+244
+00:18:31,780 --> 00:18:35,900
+تكون مرتبطة بشيء معين وهو مستوى ال hormone كمية
+
+245
+00:18:35,900 --> 00:18:38,960
+المادة الغذائية التي تصل إليها بالإضافة إلى تطور
+
+246
+00:18:38,960 --> 00:18:42,480
+الخلايا المحيطة فيهاكده انا بقول ان البويضة ما
+
+247
+00:18:42,480 --> 00:18:48,120
+بتطلع لحالها ولكن تطلع متحوصلة داخل غلاف بسميه
+
+248
+00:18:48,120 --> 00:18:52,280
+follicle ال follicle هو عبارة عن سائل يحيط به cell
+
+249
+00:18:52,280 --> 00:18:57,120
+membrane يحيط به خلايا تجريبا ان ال human ovary
+
+250
+00:18:57,120 --> 00:19:01,920
+حوالي 120 يوم
+
+251
+00:19:01,920 --> 00:19:05,820
+تحتاج من ال primary follicle علشان تصل إلى مرحلة
+
+252
+00:19:05,820 --> 00:19:11,660
+ال secondary follicleوبينما تحتاج إلى 71 يوم علشان
+
+253
+00:19:11,660 --> 00:19:15,480
+تنمو ال secondary follicle وتكون جاهزة للانتقال
+
+254
+00:19:15,480 --> 00:19:21,400
+إلى مرحلة أخرى وهي مرحلة ما قبل التطوير 120 يوم،
+
+255
+00:19:21,400 --> 00:19:28,980
+70، 180 يوم، 180، 190 يوم، 191 يوم هذه الدورة اللي
+
+256
+00:19:28,980 --> 00:19:34,180
+بتلتقلها أو تستهلكها البويضة مرورا من ال primary
+
+257
+00:19:34,180 --> 00:19:38,800
+follicle حتى المرحلة ما قبل التطويرخلال هذه الفترة
+
+258
+00:19:38,800 --> 00:19:42,800
+الـ 120 plus الـ 71 يوم بيصير maturation الـ
+
+259
+00:19:42,800 --> 00:19:46,600
+Oocyte تكتسب .. تتراكم فيها كمية كبيرة جدا من الـ
+
+260
+00:19:46,600 --> 00:19:50,380
+cytoplasm بالاضافة إلى الهضيات والمواد الغذائية
+
+261
+00:19:50,380 --> 00:19:54,600
+التي تعتبر .. هي عبارة عن مصدر الغذاء المباشر
+
+262
+00:19:54,600 --> 00:19:59,580
+والأول للجنين بعد عملية ال fertilization وجاب
+
+263
+00:19:59,580 --> 00:20:03,920
+العملية التكوين لـ placenta في عندى خلايا الخلايا
+
+264
+00:20:03,920 --> 00:20:07,950
+دي بتتنقسم يعني تحتاج إلى مواد غذائيةتستمدها من
+
+265
+00:20:07,950 --> 00:20:12,830
+الـCytoplasm المتراكم داخل الـFollicle تحتاجها بعد
+
+266
+00:20:12,830 --> 00:20:16,310
+عملية الـFertilization مباشرة وقبل عملية
+
+267
+00:20:16,310 --> 00:20:19,490
+الـImplantation وتكوين الـPlasma طبعاً هذه المادة
+
+268
+00:20:19,490 --> 00:20:23,250
+الموجودة في الـCytoplasm الخاص بالـFollicle بيحتوى
+
+269
+00:20:23,250 --> 00:20:27,570
+على جين Product مهم جدا في عملية Transcription and
+
+270
+00:20:27,570 --> 00:20:32,550
+Regulation تتحكم في مراحل تكوين وتطور الجنين تحت
+
+271
+00:20:32,550 --> 00:20:37,000
+مصطلح بيسميه Embryogenesis، تخليق الجنينبالـ
+
+272
+00:20:37,000 --> 00:20:42,920
+Embryo الـ Ogonia بتكون نكت يعني غير محاطة في
+
+273
+00:20:42,920 --> 00:20:48,240
+المرحلة الجنينية الـ Ogonia بتكون نكت غير محاطة
+
+274
+00:20:48,240 --> 00:20:52,540
+بأي نوع من أنواع الخلايا ولكن بعد انقسم الميوزي
+
+275
+00:20:52,540 --> 00:20:58,720
+تبدأ الخلايا تحيط بالـ Ogonium لتكوين ما يُعرف
+
+276
+00:20:58,720 --> 00:21:04,260
+باسم الـ Primary Oocyte لمجرد الحدوث الميلاد لـ
+
+277
+00:21:04,260 --> 00:21:11,530
+Primary Oocyteبتكتمل علشان تحصل على غشاء محاط
+
+278
+00:21:11,530 --> 00:21:15,050
+بكمية كبيرة جدا من الـ granulosa cell فبسميها هنا
+
+279
+00:21:15,050 --> 00:21:19,450
+primary follicle هذا التركيب كله بسميه primary
+
+280
+00:21:19,450 --> 00:21:22,670
+follicle طبعا ال primary follicle في عندها غشاء
+
+281
+00:21:22,670 --> 00:21:27,450
+رقيق جدا لا يسمح بدخول المواد الغذائية إلا بناء
+
+282
+00:21:27,450 --> 00:21:31,890
+على حاجة الخلية بسميها zona pellucida في الغالب
+
+283
+00:21:31,890 --> 00:21:37,590
+يسموها ZP و هي zona pellucidaشفافة، non-cellular
+
+284
+00:21:37,590 --> 00:21:40,290
+من الـ brain تسمح لدخول المواد التي تحتاجها
+
+285
+00:21:40,290 --> 00:21:42,870
+الخلية، نسميها zona pellucida هذه الـ zona
+
+286
+00:21:42,870 --> 00:21:46,510
+pellucida تحتوي على الـ sperm receptor فهي مهمة في
+
+287
+00:21:46,510 --> 00:21:50,290
+عملية ال fertilization تحتوي على compound مهم جدا
+
+288
+00:21:50,290 --> 00:21:55,110
+في نجاح عملية ال fertilization و بقاء الجنين و
+
+289
+00:21:55,110 --> 00:22:00,290
+بقاء الخلايا و إبقاء الخلايا قدرتها على القسام بعد
+
+290
+00:22:00,290 --> 00:22:04,120
+عملية ال fertilizationيعني بدون الـ ZP و الـ
+
+291
+00:22:04,120 --> 00:22:07,160
+Zoonopilicida مافي حاجة اسمها fertilization بدون
+
+292
+00:22:07,160 --> 00:22:10,600
+الـ ZP و الـ Zoonopilicida مافي حاجة اسمها خلايا
+
+293
+00:22:10,600 --> 00:22:14,600
+قادرة على انقسام وتكوين الجنين بالشكل المطلوب بدون
+
+294
+00:22:14,600 --> 00:22:17,280
+الـ Zoonopilicida مافي حاجة اسمها implantation
+
+295
+00:22:17,280 --> 00:22:21,680
+انغراض في بطاقة الرحيل هذا مهم جدا هذا الشكل الـ
+
+296
+00:22:21,680 --> 00:22:27,560
+ovary الخاص بالفيميل طبعا ال .. ال .. ال .. ال
+
+297
+00:22:27,560 --> 00:22:31,230
+primary oocyte بتكون منغمسةداخل ال ovary مابتصحب
+
+298
+00:22:31,230 --> 00:22:34,690
+على الصفح إلا عند الحجم و هي فترة طبيبية ال
+
+299
+00:22:34,690 --> 00:22:39,710
+primordial follicle ال primary follicle اللي فيها
+
+300
+00:22:39,710 --> 00:22:43,850
+primary oocyte ال secondary follicle اللي فيها
+
+301
+00:22:43,850 --> 00:22:48,290
+secondary oocyte في هنا جراب بسميه graphian
+
+302
+00:22:48,290 --> 00:22:52,930
+follicle وهي عبارة عن حواصلة كبيرة من حيث الحجم
+
+303
+00:22:52,930 --> 00:22:55,990
+تحتوى على كمية كبيرة جدا من ال cytoplasm والمواد
+
+304
+00:22:55,990 --> 00:23:01,170
+الغذائية بالإضافة إلى إنها تحتوي على الناضجة هنا
+
+305
+00:23:01,170 --> 00:23:05,730
+بصير عملية ال ovulation التبويض تخرج الفوايدة و
+
+306
+00:23:05,730 --> 00:23:09,810
+بمجرد خروج الفوايدة ما بسميها oocyte الصحة سميها
+
+307
+00:23:09,810 --> 00:23:14,250
+mature oocyte او بس عفوا الصحة سميها mature egg او
+
+308
+00:23:14,250 --> 00:23:17,510
+egg طبعا بعضهم اختلفوا يسموها egg ولا يسموها
+
+309
+00:23:17,510 --> 00:23:21,730
+oocyte يسموها egg ولا يسموها mature oocyte مش هنجف
+
+310
+00:23:21,730 --> 00:23:25,060
+على هذا الاختلاف ولكنبتعرف أنه في عدة Primary
+
+311
+00:23:25,060 --> 00:23:27,720
+Follicle فيها Primary Oocyte Secondary Follicle
+
+312
+00:23:27,720 --> 00:23:31,040
+فيها Secondary Oocyte Graphene Follicle هي عبارة
+
+313
+00:23:31,040 --> 00:23:34,760
+عن حويصة بتحتوي على البويضة الناضجة وتحيط فيها
+
+314
+00:23:34,760 --> 00:23:37,580
+كمية كبيرة جدا من الـCytoplasm اللازم في بقاء
+
+315
+00:23:37,580 --> 00:23:41,240
+الخلايا فيما بعد وينقسمها بعد كده بيصير ال
+
+316
+00:23:41,240 --> 00:23:46,320
+ovulation وخروج البويضة الناضجة ال Graphene
+
+317
+00:23:46,320 --> 00:23:49,580
+Follicle ما بيصير له degradation فيما بعد لأ بتحول
+
+318
+00:23:49,580 --> 00:23:53,960
+إلى Corpus Luteum وهو عبارة عن الجسم الأصفرالذي
+
+319
+00:23:53,960 --> 00:23:57,920
+يلعب دورة مهمة في بقاء الحمل لفترة زمانية معينة
+
+320
+00:23:57,920 --> 00:24:01,220
+حتى تكوين الـ Placenta بعد ما يؤدي وظيفته بـ
+
+321
+00:24:01,220 --> 00:24:04,620
+Psilodegeneration ويتحول إلى الـ Corpus الـ Lutein
+
+322
+00:24:04,620 --> 00:24:08,000
+يتحول إلى الـ Corpus البيكاني وعبارة عن الجسم
+
+323
+00:24:08,000 --> 00:24:13,140
+الأبيض، دليل على التلايفه طيب، في عند بعض
+
+324
+00:24:13,140 --> 00:24:17,680
+الهرمونات التي تساهم في نمو ونضوج الخلايا مثلًا،
+
+325
+00:24:17,680 --> 00:24:20,200
+من أشر هذه الهرمونات الـ FSH
+
+326
+00:24:22,180 --> 00:24:25,500
+أو Stimulating Hormone و الـ L-H-Lotilizing
+
+327
+00:24:25,500 --> 00:24:30,220
+Hormone هذه الهرمونات مهمة جدا تفرز من بعض الغدد
+
+328
+00:24:30,220 --> 00:24:33,380
+اللي بحنا نتكلم عنها بالشكل الكامل و بتأثر على الـ
+
+329
+00:24:33,380 --> 00:24:36,740
+Ovary و خاصة على الـ Graafian Follicle من أجل
+
+330
+00:24:36,740 --> 00:24:40,420
+تنضاج القويضة و أظفة للخارج في عملية بتسميها
+
+331
+00:24:40,420 --> 00:24:47,780
+Ovulation حوالي 10 إلى 12 ساعة لازم جاب العملية ال
+
+332
+00:24:47,780 --> 00:24:52,170
+Ovulation لازم يصير استكمال للقسام الميوزييعني من
+
+333
+00:24:52,170 --> 00:24:57,490
+القسام الميوزي والخلايا اللي وقفت في مرحلة معينة
+
+334
+00:24:57,490 --> 00:25:01,490
+من القسام الميوزي لازم تستكمل القسام الميوزي قبل
+
+335
+00:25:01,490 --> 00:25:05,150
+.. الأول طبعا .. قبل عملية ال maturation أو قبل
+
+336
+00:25:05,150 --> 00:25:09,950
+عملية ال ovulation ب 12 ساعة على الأقل يعني لازم
+
+337
+00:25:09,950 --> 00:25:14,830
+الخلية البويضة تكون تخلصت من منتصف عدد الكرومزومات
+
+338
+00:25:14,830 --> 00:25:19,180
+وظهرت على هيئةSecondary Oocyte Plus Ferrous Polar
+
+339
+00:25:19,180 --> 00:25:23,700
+Body جاب يد 12 ساعة كحد أقصى من عملية الـ
+
+340
+00:25:23,700 --> 00:25:28,480
+ovulation طبعا الـ Utilizing hormone هو عبارة عن
+
+341
+00:25:28,480 --> 00:25:31,700
+هرمون مهم جدا يفرز من الـ anterior loop و البطيطة
+
+342
+00:25:31,700 --> 00:25:36,320
+الجلان وبيأثر على ريسبتور مهم جدا في الـ Gravian
+
+343
+00:25:36,320 --> 00:25:40,600
+Follicle علشان يساعد في عملية الـ ovulation طبعا
+
+344
+00:25:40,600 --> 00:25:46,170
+هذا بيسميها Theca Interna Cellموجودة في منطقة الـ
+
+345
+00:25:46,170 --> 00:25:49,470
+Gravian Follicle طبعا هذه ثيكا انترنا انترنا سل
+
+346
+00:25:49,470 --> 00:25:54,490
+بتفرز حاجة بتسمى Androgynous اللي تخترق ال
+
+347
+00:25:54,490 --> 00:25:56,910
+membrane الخاص بالجرانيولوزا و بتأثر على
+
+348
+00:25:56,910 --> 00:25:59,570
+الجرانيولوزا السالي طب ليش بتأثر على الجرانيولوزا
+
+349
+00:25:59,570 --> 00:26:04,690
+السالي؟ علشان تفرز طبعا هرمونات معينة ومواد معينة
+
+350
+00:26:04,690 --> 00:26:08,290
+ال influence of FSH induced الجرانيولوزا السالي
+
+351
+00:26:08,290 --> 00:26:11,540
+الواحد يتعرفنا ال autolysing hormone إيش بيثورالـ
+
+352
+00:26:11,540 --> 00:26:14,340
+FSH هو الـ Follicle Stimulating Hormone اللي بيفرز
+
+353
+00:26:14,340 --> 00:26:17,860
+من الـ anterior lobe و الـ pituitary gland بيحفظ و
+
+354
+00:26:17,860 --> 00:26:21,840
+بيساعد الـ granulosa cell على تخليق إنزيم معين
+
+355
+00:26:21,840 --> 00:26:27,740
+بتسميه الـ Aromatase enzyme اللي بيحفظ الثيكة من
+
+356
+00:26:27,740 --> 00:26:31,200
+أجل تحويل الأندروجين إلى أستروجين شو هو
+
+357
+00:26:31,200 --> 00:26:35,500
+الأستروجين؟ الأستروجين مسمّال أخر أسترديول أو E2
+
+358
+00:26:35,500 --> 00:26:39,840
+اللي هو يعتبر indication على مدى تطور الخلايا و
+
+359
+00:26:39,840 --> 00:26:44,060
+انضج الكليةكل خلية .. المقصود بالخلية هنا البوايضة
+
+360
+00:26:44,060 --> 00:26:49,140
+.. كل بوايضة نادجة تستطيع أن تنتج كمية معينة من
+
+361
+00:26:49,140 --> 00:26:53,000
+الـ E2 هتكلم عن كمية الـ E2 المندجة في حالة الـ
+
+362
+00:26:53,000 --> 00:26:57,040
+ovulation كم هتكون في حالة ال stimulation ان شاء
+
+363
+00:26:57,040 --> 00:27:01,380
+الله تحت عنوان stimulation protocol السيدات اللي
+
+364
+00:27:01,380 --> 00:27:04,980
+بيخضع لل IVF أو للإيجزي تدخل stimulation protocol
+
+365
+00:27:04,980 --> 00:27:10,040
+عشان طيب 12 خلية و 20 خلية بأجازة بوايضة يعنيناضجة
+
+366
+00:27:10,040 --> 00:27:15,180
+عشان يزيد فرصة ال fertilization The estradiol this
+
+367
+00:27:15,180 --> 00:27:18,540
+type of hormone play a very important role in
+
+368
+00:27:18,540 --> 00:27:22,240
+stimulating the formation of LH receptor on the
+
+369
+00:27:22,240 --> 00:27:27,320
+granulosa cell يعني ال FSH هرمون افرز تم افرازه
+
+370
+00:27:27,320 --> 00:27:30,400
+حفظ ال granulosa cell عشان تفرز ال aromatase
+
+371
+00:27:30,400 --> 00:27:34,400
+enzyme ال aromatase enzyme اللي افرز حول ال
+
+372
+00:27:34,400 --> 00:27:39,840
+androgens إلى estrogensالـ Estrogen أو الـ
+
+373
+00:27:39,840 --> 00:27:44,260
+Estradiol هرمون بلعب دور مهم جدا علشان ينشط الـ
+
+374
+00:27:44,260 --> 00:27:48,420
+Receptor الموجودة في الـ Theca و الموجودة في الـ
+
+375
+00:27:48,420 --> 00:27:53,160
+Granulosa بشكل أساسي لإستقبال القلقش هرمون طب أي
+
+376
+00:27:53,160 --> 00:27:56,360
+Receptor؟ الـ Receptor خاص بالقلقش هرمون لأنه في
+
+377
+00:27:56,360 --> 00:27:59,220
+قانون في الـ Endocrine أن كل هرمون له Receptor
+
+378
+00:27:59,220 --> 00:28:02,780
+معين طب إيش دخل ال Receptor بتاعت القلقش؟ لأنه
+
+379
+00:28:02,780 --> 00:28:07,910
+مجرد تنشيط هرمونالـ Receptor خاصة بالـ LH الموجودة
+
+380
+00:28:07,910 --> 00:28:10,010
+في الـ Granulosa Cell المحيطة بالـ Graafian
+
+381
+00:28:10,010 --> 00:28:15,310
+Follicle ومجرد إفراز الـ LH هتستقبل هذه الـ
+
+382
+00:28:15,310 --> 00:28:19,010
+Follicle لـ Utilizing Hormone الذي يساهم بشكل كبير
+
+383
+00:28:19,010 --> 00:28:22,790
+جدا على انفجار الـ Graafian Follicle وخروج
+
+384
+00:28:22,790 --> 00:28:27,450
+البوايطة في مصطلح نسميه Ovulation في مصطلح نسميه
+
+385
+00:28:27,450 --> 00:28:32,430
+Ovulation طبعا هذه النقطة الحمراء هي عبارة ..
+
+386
+00:28:32,430 --> 00:28:36,400
+المحيطة فيها النقطة هي عبارة عن الـ Oocyteالخلايا
+
+387
+00:28:36,400 --> 00:28:39,520
+المحيطة فيها كلها تبارع عن cumulus cell و
+
+388
+00:28:39,520 --> 00:28:43,340
+granulosa cell يعني هذه كلها خلايا كرمس cumulus
+
+389
+00:28:43,340 --> 00:28:49,300
+cell و granulosa cell تدعم نضوج هذه القواعدة هذه
+
+390
+00:28:49,300 --> 00:28:52,680
+الـ Follicle Fluid وهذه كلها الـ membrane اللي
+
+391
+00:28:52,680 --> 00:28:57,240
+سمته ZP أو Zona Pellucida وهذه طبقة blood vessels
+
+392
+00:28:57,240 --> 00:29:01,980
+وهذه الـ Internal Fecal Cell اللي حكيت أن الـ
+
+393
+00:29:01,980 --> 00:29:07,120
+Internal Fecal Cellتلعب دور كبير جداً في إنتاج أو
+
+394
+00:29:07,120 --> 00:29:10,720
+في تحفيز أو .. عفوا .. في تحفيز الـ granulosa cell
+
+395
+00:29:10,720 --> 00:29:16,620
+من أجل إنتاج .. عفوا ال .. الـ internal fecal cell
+
+396
+00:29:16,620 --> 00:29:20,540
+هي التي تنتج الـ androgens هرمون أو material أو
+
+397
+00:29:20,540 --> 00:29:25,000
+substance اللي بتخترق الـ granulosa cell و بتحفزها
+
+398
+00:29:25,000 --> 00:29:29,120
+فيما بعد تأثير الـ FSH هرمون لإنتاج الاروماتيز
+
+399
+00:29:29,120 --> 00:29:33,170
+اللي بيحول الاندروجين إلى أستروجين اللي بيحفزالـ
+
+400
+00:29:33,170 --> 00:29:36,270
+Utilizing Hormone Receptor وبيخلّيها قادرة أن
+
+401
+00:29:36,270 --> 00:29:40,610
+تستجيب للـ LH مما يساهم ويسهّل عملية الـ ovulation
+
+402
+00:29:40,610 --> 00:29:47,830
+هذا دياجرام بيمثل الهرمونات التي تستخدم فلو قلت في
+
+403
+00:29:47,830 --> 00:29:50,490
+عندي gonadotropin releasing hormone أو
+
+404
+00:29:50,490 --> 00:29:55,170
+gonadotropin هرمون المتمثل في الـ LH و الـ FSH الـ
+
+405
+00:29:55,170 --> 00:29:59,530
+FSH مهم جداً لـ maturation الـ LH مهم جداً لـ
+
+406
+00:29:59,530 --> 00:30:03,550
+ovulationهي الـ oocyte الـ event in ovary الـ
+
+407
+00:30:03,550 --> 00:30:07,510
+oocyte تطورها بيصير ovulation عندما يفرز الألش
+
+408
+00:30:07,510 --> 00:30:13,030
+بكمية كبيرة جدا بعد ان ال oocyte المخصبة الفوليكل
+
+409
+00:30:13,030 --> 00:30:17,890
+الموجودة كانت فيها تتحول لقربس اليوتيا بمجرد نمو
+
+410
+00:30:17,890 --> 00:30:21,450
+البوايدة بتفرز البوايدة النامية أستروجين أو
+
+411
+00:30:21,450 --> 00:30:25,930
+أستراديول هرمون بكمية معينة جدا بمجرد حدوث ال
+
+412
+00:30:25,930 --> 00:30:31,330
+fertilization يفرز بعد كده روجسترون هرمونالـ
+
+413
+00:30:31,330 --> 00:30:34,890
+menstrual cycle أو الدورة الشهرية لأننا هنتكلم
+
+414
+00:30:34,890 --> 00:30:37,910
+عنها بالتفصيل وإيش الأحداث اللي بتصير فيها وإيش
+
+415
+00:30:37,910 --> 00:30:41,790
+الهرمونات اللي بتشغل إذا قبل هذه العملية في عندي
+
+416
+00:30:41,790 --> 00:30:47,070
+هرمون أستروجين هرمون بروجسترون هرمون القلقاتش
+
+417
+00:30:47,070 --> 00:30:51,230
+وهرمون أفأساتش هذه الهرمونات المهمة جدا التي تدخل
+
+418
+00:30:51,230 --> 00:30:57,610
+في عملية الـ oocyte maturation و ال ovulation و ال
+
+419
+00:30:57,610 --> 00:31:05,130
+fertilization فيما بعدطبعا قبل ما نتكلم عن هذه
+
+420
+00:31:05,130 --> 00:31:09,870
+العملية في عنده كل cycle في عنده حوالي 100 فوليكل
+
+421
+00:31:09,870 --> 00:31:14,170
+بيصير النضوج لها هناك قال 1000 of a cycle لأن
+
+422
+00:31:14,170 --> 00:31:18,270
+الفوليكل ممكن تحتوي على أكتر من بوايدة فقط اللي
+
+423
+00:31:18,270 --> 00:31:22,070
+بينضج هي عبارة عن تلاتة فوليكل و لازم التلاتة
+
+424
+00:31:22,070 --> 00:31:25,350
+فوليكل عشان تنضج يكون ال diameter الخاص فيها أكتر
+
+425
+00:31:25,350 --> 00:31:30,390
+من 8 mm قبل ال ovulation البوايدة اللتي يجب انها
+
+426
+00:31:31,670 --> 00:31:35,470
+before ovulation occur the average diameter of the
+
+427
+00:31:35,470 --> 00:31:42,030
+dominant follicle should be between 22 to 24 mm ده
+
+428
+00:31:42,030 --> 00:31:46,790
+ال range حوالي من 16 ل 18 ل 36 علشان كده بقولي أن
+
+429
+00:31:46,790 --> 00:31:51,770
+أي بويضة أو أي follicle تحتوي على بويضة ناضجة لازم
+
+430
+00:31:51,770 --> 00:31:55,230
+يكون في عند ال diameter لو أنا قصتها يكون أقل شيء
+
+431
+00:31:55,230 --> 00:32:00,670
+18 mm في ال follicular growth initial follicular
+
+432
+00:32:00,670 --> 00:32:05,670
+growthis gonadotropin independent يعني أول ما تبدأ
+
+433
+00:32:05,670 --> 00:32:11,170
+الفوليكل بالمضوج بتكون in gonadotropin independent
+
+434
+00:32:11,170 --> 00:32:13,770
+but continuous growth depending on the minimum
+
+435
+00:32:13,770 --> 00:32:17,890
+level of gonadotropin principle of a such يعني
+
+436
+00:32:17,890 --> 00:32:22,610
+بداية نمو و تطور الفوليكل ما بتكون معتمدة على
+
+437
+00:32:22,610 --> 00:32:26,410
+gonadotropin بشكل أساسي ولكن فيما بعد تحتاج إلى
+
+438
+00:32:26,410 --> 00:32:29,770
+gonadotropin و أهمه من ال a such ولكن بكميات قليلة
+
+439
+00:32:29,770 --> 00:32:33,230
+جداDuring the phase of gonadotropin-induced
+
+440
+00:32:33,230 --> 00:32:36,170
+growth, a domain enlarging follicle became
+
+441
+00:32:36,170 --> 00:32:40,230
+independent of FSH and secreted a large amount of
+
+442
+00:32:40,230 --> 00:32:43,910
+inhibin طالما هي لا تعتمد على ال FSH، إذا أنت تفرز
+
+443
+00:32:43,910 --> 00:32:49,190
+مثبت بسميه inhibin، يعمل على تطبيق إفراز ال FSH
+
+444
+00:32:49,190 --> 00:32:54,170
+طالما أنا كموايدة ما بدي ال FSH، ليش أخلي ال
+
+445
+00:32:54,170 --> 00:32:58,850
+antireliab تفرزه؟ فبفرز هرمون اسمه inhibin بحبط و
+
+446
+00:32:58,850 --> 00:33:04,920
+بطبط نموأو عفوًا بيهبط و بيثبت إفراز الـ FSH
+
+447
+00:33:04,920 --> 00:33:09,120
+الانهيبين suppress the secretion of FSH by
+
+448
+00:33:09,120 --> 00:33:12,600
+pituitary gland and when they .. when the FSH
+
+449
+00:33:12,600 --> 00:33:16,200
+level fall below the level threshold the other
+
+450
+00:33:16,200 --> 00:33:19,940
+developing follicles which are still dependent on
+
+451
+00:33:19,940 --> 00:33:23,640
+FSH for maintenance become at risk هنا في مشكلة
+
+452
+00:33:23,640 --> 00:33:28,580
+طالما أنا هويضة وصلت للحد المطلوب ومش محتاج لل FSH
+
+453
+00:33:28,580 --> 00:33:32,810
+عشان ينضج زيادة عن نسوةببدأ افرز هرمون اسمه
+
+454
+00:33:32,810 --> 00:33:36,770
+الانهيبين، فبثبت افراز الـ FSH من الـ anterior
+
+455
+00:33:36,770 --> 00:33:41,310
+pituitary gland في نفس اللحظة، في فوليكل أخرى لم
+
+456
+00:33:41,310 --> 00:33:45,190
+تصل إلى الدياميتال المجلوب هو الـ 18 فبتحتاج الـ
+
+457
+00:33:45,190 --> 00:33:50,230
+FSH، فمافيش FSH فبتروح أتراجة، عشان كده عدد
+
+458
+00:33:50,230 --> 00:33:55,390
+الفوليكل 50يحتوي minimum على ألف بوايدة مش كل
+
+459
+00:33:55,390 --> 00:33:58,390
+البوايدات اتصل بال maturation فبلاجي في النهاية
+
+460
+00:33:58,390 --> 00:34:03,670
+محصلة تلت بوايدات كحد أقصى هي البصرة لـ maturation
+
+461
+00:34:03,670 --> 00:34:08,330
+هنتافي بهذا القدر في هذه المحاضرة على أمل أن
+
+462
+00:34:08,330 --> 00:34:12,910
+أستكمل عملية ال maturation لل oocyte أو ال
+
+463
+00:34:12,910 --> 00:34:16,870
+oogonium أو ال oogenesis process في المحاضرة
+
+464
+00:34:16,870 --> 00:34:21,830
+القادمة ان شاء الله دمتم في حفظ الله و رعايتكعلى
+
+465
+00:34:21,830 --> 00:34:26,450
+أمل أن أرتح في الأسبوع القادم بأمر الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/04ZuGxhhn40.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/04ZuGxhhn40.srt
new file mode 100644
index 0000000000000000000000000000000000000000..d7075609eccec2d9ab9803f9a2aa209b29549801
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/04ZuGxhhn40.srt
@@ -0,0 +1,1747 @@
+1
+00:00:01,920 --> 00:00:05,800
+باسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,800 --> 00:00:11,640
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين أرجو من 
+
+3
+00:00:11,640 --> 00:00:16,060
+الله الكريم أن تكونوا بخير جميعا استكمالا لما 
+
+4
+00:00:16,060 --> 00:00:20,960
+تحدثنا فيه في المحاضرة السابقة حول عملية انتقال 
+
+5
+00:00:20,960 --> 00:00:25,060
+النطف الذكرية في الـ reproductive tract الخاصة 
+
+6
+00:00:25,060 --> 00:00:28,080
+بالمرأة والنطف الأنثوية في الـ female reproductive 
+
+7
+00:00:28,080 --> 00:00:34,240
+tract ووقفنا في المحاضرة السابقة عند كلمة مهمة جدا 
+
+8
+00:00:34,240 --> 00:00:38,520
+وهي عبارة عن Coagulum حكينا أن الـ Coagulum هي 
+
+9
+00:00:38,520 --> 00:00:43,280
+عبارة عن تجلّقات بسيطة بفعل بروتينات موجودة في الـ 
+
+10
+00:00:43,280 --> 00:00:47,780
+seminal fluid تعمل معامل network الشبكة التي 
+
+11
+00:00:47,780 --> 00:00:52,580
+تحمل sperm بالداخل من الـ environment الخشنة أو 
+
+12
+00:00:52,580 --> 00:00:55,700
+الغريبة أو الضارة الموجودة في الـ reproductive
+
+13
+00:00:55,700 --> 00:01:00,020
+tract الخاصة بالأنثى وخاصة منطقة المهبل بإضافة 
+
+14
+00:01:00,020 --> 00:01:05,060
+إلى اختلاف الـ pH هذه الـ coagulant لازم يصير فيها 
+
+15
+00:01:05,060 --> 00:01:11,400
+عملية dissolving أو losing عشان تتيح الفرصة لهذا 
+
+16
+00:01:11,400 --> 00:01:16,700
+الـ sperm أن يتحرك وصولا إلى منطقة عنق الرحم بعد 
+
+17
+00:01:16,700 --> 00:01:22,040
+حوالي 30 إلى 60 دقيقة من عملية خسارة الكواكولا 
+
+18
+00:01:22,040 --> 00:01:27,360
+للبروستاتا للبروستاتا مخصصة انتجين وإنزيم بروتيوليتك
+
+19
+00:01:27,360 --> 00:01:33,520
+سيكون مفرد ويخسر السائل الكواكولاتي في السائل
+
+20
+00:01:33,520 --> 00:01:37,740
+والمنوي المهبل المادة المنوية يبدأ بالمشاركة 
+
+21
+00:01:37,740 --> 00:01:45,750
+بمجرد عملية... بمجرد عملية تحلل الكواجولام المحيط 
+
+22
+00:01:45,750 --> 00:01:49,330
+بالـ sperm بتاع بعض الإنزيمات التي تكون موجودة في 
+
+23
+00:01:49,330 --> 00:01:52,930
+الـ seminal fluid وأشهرها البروستاتيك specific antigen 
+
+24
+00:01:52,930 --> 00:01:55,330
+أو الـ prostate-specific antigen بالإضافة إلى الـ
+
+25
+00:01:55,330 --> 00:01:59,530
+proteolytic enzyme هذا يؤدي إلى تحلل الكواجولام،
+
+26
+00:01:59,530 --> 00:02:02,410
+تكسر البروتينات التي تعمل الـ coagulation حول الـ
+
+27
+00:02:02,410 --> 00:02:06,320
+sperm فبالتالي الـ sperm بيكون حر و يبدأ يستطيع 
+
+28
+00:02:06,320 --> 00:02:11,720
+الحركة والسباحة في اتجاه قناة فالوب a critical 
+
+29
+00:02:11,720 --> 00:02:15,380
+element in the sperm motility is the availability
+
+30
+00:02:15,380 --> 00:02:19,580
+of fructose أهم شغل في الـ sperm motility توفر كمية 
+
+31
+00:02:19,580 --> 00:02:24,260
+كافية من الفركتوز because of their lack of
+
+32
+00:02:24,260 --> 00:02:27,360
+cytoplasmic spermatozoa required an external 
+
+33
+00:02:27,360 --> 00:02:32,680
+energy source بدون الفركتوز ما في قدرة على الحركة 
+
+34
+00:02:32,680 --> 00:02:36,420
+علشان كده ممكن بعض الذكور يكون عنده الـ sperm طبيعي 
+
+35
+00:02:36,420 --> 00:02:41,420
+الحركة غير طبيعية بفعل شيء واحد وهو كمية الـ
+
+36
+00:02:41,420 --> 00:02:44,440
+fructose الموجودة في السائل المنوي والتي تستخدم كمصدر
+
+37
+00:02:44,440 --> 00:02:49,600
+أساسي للطاقة الخاصة بالـ sperm غير موجودة فلو تم 
+
+38
+00:02:49,600 --> 00:02:55,280
+عمل فحص للـ fructose test الذي يُهمَل بفعل بعض المراكز
+
+39
+00:02:55,280 --> 00:03:00,340
+أو بعض المختبرات هيمكن تشخيص الحالة المرضية يكون
+
+40
+00:03:00,340 --> 00:03:03,680
+علاجها بسيط جدا هي تناول فواكه تحتوي على الفركتوز
+
+41
+00:03:03,680 --> 00:03:06,880
+أو أخذ بعض المكملات الغذائية التي تحتوي على 
+
+42
+00:03:06,880 --> 00:03:11,020
+الفركتوز usually for most cells spermatozoa have a 
+
+43
+00:03:11,020 --> 00:03:13,560
+specific requirement for fructose rather than 
+
+44
+00:03:13,560 --> 00:03:17,300
+glucose the more commonly utilized carbohydrate
+
+45
+00:03:17,300 --> 00:03:21,100
+energy source بيحكيلي أن الـ spermatozoa أو الـ
+
+46
+00:03:21,100 --> 00:03:25,690
+sperm كنطفة أو كخلية تختلف عن الخلايا الأخرى في 
+
+47
+00:03:25,690 --> 00:03:29,910
+مصدرها للطاقة فمعظم الخلايا تستخدم الجلوكوز كمصدر
+
+48
+00:03:29,910 --> 00:03:34,770
+للطاقة باستثناء الـ spermatozoa تستخدم الفركتوز
+
+49
+00:03:34,770 --> 00:03:39,050
+وذلك لسببين حركتها السريعة جدا والتي تحتاج إلى 
+
+50
+00:03:39,050 --> 00:03:43,330
+كمية هائلة من الطاقة بشكل مستمر فبالتالي احتراق
+
+51
+00:03:43,330 --> 00:03:48,000
+الفركتوز لإنتاج الطاقة أسرع من احتراق الجلوكوز إلى
+
+52
+00:03:48,000 --> 00:03:51,180
+بعض الإنزيمات المسؤولة عن احتراق الجلوكوز زي 
+
+53
+00:03:51,180 --> 00:03:54,240
+الـ Hexokinase وبالتالي اللي يمكن استخدامه بالطريقة
+
+54
+00:03:54,240 --> 00:03:59,400
+التي تستخدم فيها الفركتوز الـ hexokinase أو ثاني
+
+55
+00:03:59,400 --> 00:04:05,080
+حاجز أو ثاني خطر بيواجه الـ Sperm عبارة عن منطقة 
+
+56
+00:04:05,080 --> 00:04:07,700
+عنق الرحم مدخل عنق الرحم
+
+57
+00:04:11,120 --> 00:04:14,980
+it is not only very small but it is blocked by 
+
+58
+00:04:14,980 --> 00:04:19,260
+cervical mucus اتخلص الـ sperm من الـ pH الخاص 
+
+59
+00:04:19,260 --> 00:04:24,400
+بالمهبل وصل لعتاب عنق الرحم يصطدم بخطر ثاني وهو 
+
+60
+00:04:24,400 --> 00:04:27,980
+عبارة عن مدخل عنق الرحم مدخل عنق الرحم فيه مشكلتين 
+
+61
+00:04:27,980 --> 00:04:32,060
+المشكلة الأولى أنه very close أو very narrow very
+
+62
+00:04:32,060 --> 00:04:36,840
+small الشيء الثاني أنه مغلق بكمية كبيرة جدا من الـ
+
+63
+00:04:36,840 --> 00:04:41,860
+مخاط تسمى cervical mucus طبعا during the most
+
+64
+00:04:41,860 --> 00:04:44,640
+time of menstrual cycle الـ cervical mucus is very
+
+65
+00:04:44,640 --> 00:04:50,600
+thick and sticky and very difficult to penetrate خلال
+
+66
+00:04:50,600 --> 00:04:54,160
+عملية الدورة الشهرية بنلاقي عنق الرحم مغلق
+
+67
+00:04:54,160 --> 00:04:57,960
+بكمية كبيرة جدا من المخاط الغليظة التي يصعب
+
+68
+00:04:57,960 --> 00:05:01,910
+اختراقها وهذا نوع من أنواع الحماية، وهذا نوع من 
+
+69
+00:05:01,910 --> 00:05:07,510
+أنواع الحماية حتى لو الـ Sperm صار الجماع في
+
+70
+00:05:07,510 --> 00:05:11,730
+غير موضع الإباضة يعني القريب من الدورة الشهرية 
+
+71
+00:05:11,730 --> 00:05:15,130
+أو فترة الدورة الشهرية يصعب على الـ 
+
+72
+00:05:15,130 --> 00:05:20,670
+sperm اختراق هذه الكمية الكثيفة من المخاط طب شو 
+
+73
+00:05:20,670 --> 00:05:23,970
+اللي بيخلي المخاط thick أو sticky؟ هي 
+
+74
+00:05:23,970 --> 00:05:27,290
+حاجة بتسميها cervical myosin هي نوع من أنواع
+
+75
+00:05:27,290 --> 00:05:30,550
+الجليكوبروتين وهو عبارة عن with high carbohydrate 
+
+76
+00:05:30,550 --> 00:05:33,770
+composition الجليكوبروتين هو عبارة عن كمية كبيرة 
+
+77
+00:05:33,770 --> 00:05:37,310
+جدا من الكربوهيدرات متصلة مع البروتين and soluble 
+
+78
+00:05:37,310 --> 00:05:40,330
+compound cervical mucus is not ready for penetration
+
+79
+00:05:40,330 --> 00:05:46,340
+يعني هذه الـ cervical myosin تجعل المخاط الموجود 
+
+80
+00:05:46,340 --> 00:05:49,860
+على مقدمة عنق الرحم أو مدخل عنق الرحم صعب 
+
+81
+00:05:49,860 --> 00:05:53,640
+اختراقه طب إيه اللي بيخلي الـ sperm قادر على
+
+82
+00:05:53,640 --> 00:05:56,820
+اختراقه؟ بيقول لك في أيام الإباضة اليوم 13 واليوم 
+
+83
+00:05:56,820 --> 00:06:01,800
+14 الهرمونات التي تفرز بفعل المبيض زي الـ 
+
+84
+00:06:01,800 --> 00:06:05,300
+estrogenic hormone بعمل على تكوين الـ estrogenic
+
+85
+00:06:05,300 --> 00:06:10,140
+environment هذا اللي بتخلي المخاط loose
+
+86
+00:06:10,140 --> 00:06:14,350
+بتعمل تغيير في التكوين وفي التركيب 
+
+87
+00:06:14,350 --> 00:06:19,630
+وفي قوام مخاط عنق الرحم فبيصير بعد ما كان thick 
+
+88
+00:06:19,630 --> 00:06:24,170
+و sticky و viscous بيصير watery سهل 
+
+89
+00:06:24,170 --> 00:06:29,010
+الـ penetration بفعل أسباب بتتصور متى؟ في لحظة أو
+
+90
+00:06:29,010 --> 00:06:32,270
+أيام الإباضة بيصير إفراز كمية كبيرة جدا من 
+
+91
+00:06:32,270 --> 00:06:36,370
+الإستروجين بيكون استروجينك environment بيغير طبيعة
+
+92
+00:06:36,370 --> 00:06:42,330
+مخاط عنق الرحم بيخليه من sticky إلى watery سهل الـ
+
+93
+00:06:42,330 --> 00:06:47,830
+penetration بفعل الـ sperm العائق رقم ثلاثة اللي
+
+94
+00:06:47,830 --> 00:06:51,710
+بيواجه الـ sperm هو خلال عملية الانتقال بعد دخوله 
+
+95
+00:06:51,710 --> 00:06:55,150
+عنق الرحم هو الـ immunological شو يعني 
+
+96
+00:06:55,150 --> 00:06:58,730
+immunological؟ يعني جهاز المناعة جهاز المناعة 
+
+97
+00:06:58,730 --> 00:07:02,650
+بيتعامل مع الـ sperm كأنه foreign substance وطالما 
+
+98
+00:07:02,650 --> 00:07:06,230
+هو foreign substance إذا بيحفز جهاز المناعة فبيبدأ
+
+99
+00:07:06,230 --> 00:07:12,230
+جهاز المناعة يقضي على الـ sperm بفعل الخلايا البلعمية 
+
+100
+00:07:12,230 --> 00:07:17,690
+زي النيتروفيل والـ Vagocyte المهبلية وأيضا الـ
+
+101
+00:07:17,690 --> 00:07:22,550
+عنق الرحم استخدمت استراتيجية إميونولوجية لإنقاذ الـ
+
+102
+00:07:22,550 --> 00:07:26,750
+ممرض من الانتقال والانتقال إلى الـ cervical 
+
+103
+00:07:26,750 --> 00:07:30,510
+للوصول إلى الجزء الأعلى من الـ female reproductive
+
+104
+00:07:30,510 --> 00:07:34,710
+tract والمقصود فيها الرحم وقناة فالوب 
+
+105
+00:07:34,710 --> 00:07:37,490
+لأن لو الممرض وصل للرحم وقناة فالوب
+
+106
+00:07:37,680 --> 00:07:42,340
+يعني صار فيه التهاب، التهاب يعني ممكن يصير تقرحات،
+
+107
+00:07:42,340 --> 00:07:45,860
+تقرحات يعني ممكن يصير عندي التصاقات، ligament
+
+108
+00:07:45,860 --> 00:07:49,240
+adhesion، بطانة الرحم، يعني في الغالب
+
+109
+00:07:49,240 --> 00:07:54,640
+عقم طبعا من أشهر الخلايا التي تساهم في هذه
+
+110
+00:07:54,640 --> 00:07:57,580
+الحماية هي عبارة عن الـ Neutrophil و الـ macro والـ
+
+111
+00:07:57,580 --> 00:08:01,000
+macrophage بالإضافة إلى بعض الـ monoglobulin like
+
+112
+00:08:01,000 --> 00:08:06,080
+IgA و IgG و الـ IgG بالذات لأنه صغير جدا في 
+
+113
+00:08:06,080 --> 00:08:10,920
+الحجم والـ IgA لأنه ممكن يتواجد في الإفرازات
+
+114
+00:08:10,920 --> 00:08:16,120
+فبالتالي لم يتم اختيار الـ IgA و الـ IgG عبثا ولكن الـ
+
+115
+00:08:16,120 --> 00:08:19,340
+IgG بسبب صغر حجمه فبالتالي ممكن يعمل ترشيح 
+
+116
+00:08:19,340 --> 00:08:23,500
+لأي مكان والـ IgA لأنه سهل تواجده في الإفرازات 
+
+117
+00:08:23,500 --> 00:08:28,080
+فهيكلامه بيشتغل ضد أي foreign substance بيمنعه من
+
+118
+00:08:28,080 --> 00:08:34,520
+الـ invasion السيرماتوزوه أيضا تحفز بعض هذه 
+
+119
+00:08:34,520 --> 00:08:40,200
+الدفاعات لإيقاف أكثر منها في انتقالها إلى داخل
+
+120
+00:08:40,200 --> 00:08:45,060
+عنق الرحم رغم أن السيرماتوزوه تستطيع أن تحفز أحد
+
+121
+00:08:45,060 --> 00:08:49,260
+هذه العوامل الخاصة بالإيميونولوجيكال إلا أنها 
+
+122
+00:08:49,260 --> 00:08:52,600
+تستطيع أن تتغلب عليهم وإلا كيف تصير عملية الـ
+
+123
+00:08:52,600 --> 00:08:57,460
+fertilization بعد 24 ساعة من بقاء السائل المنوي في منطقة
+
+124
+00:08:57,460 --> 00:09:01,290
+عنق الرحم تبدأ الـ Vagocyte تشتغل المتمثلة في الـ
+
+125
+00:09:01,290 --> 00:09:06,810
+Neutrophil و Macrophage بتعمل الـ Vagocytosis و
+
+126
+00:09:06,810 --> 00:09:12,050
+Engulfing للـ spermatozoa فبتعمل reduction في عدد
+
+127
+00:09:12,050 --> 00:09:16,030
+الـ spermatozoa التي قد تصل إلى الـ Oocyte فبدل ما 
+
+128
+00:09:16,030 --> 00:09:20,570
+يصل مليون بيصل 200 ألف، 300 ألف، 400 ألف، 900 ألف 
+
+129
+00:09:20,570 --> 00:09:23,970
+يعني بصلا يطلع عندي 50 مليون، 20 مليون، 30 مليون، 
+
+130
+00:09:23,970 --> 00:09:28,140
+300 مليون بيصل لكمية بالألوف فقط لغير واحد منهم
+
+131
+00:09:28,140 --> 00:09:32,620
+يستطيع تلقيه القوائد الـ swimming speed of the
+
+132
+00:09:32,620 --> 00:09:36,800
+human sperm in the fluid is approximately five
+
+133
+00:09:36,800 --> 00:09:41,220
+millimeters per minute لو أنا قرنت حركة الـ sperm 
+
+134
+00:09:41,220 --> 00:09:45,180
+في الوضع الطبيعي بنلاقي سرعة الـ sperm تصل خمسة ملي
+
+135
+00:09:45,180 --> 00:09:48,800
+متر في الدقيقة يعني بالوضع النظري المعقول و
+
+136
+00:09:48,800 --> 00:09:52,540
+الحسابات المعقولة عشان يصل للمنطقة المطلوبة منه 
+
+137
+00:09:52,540 --> 00:09:57,540
+بحتاج إلى دقائق أو ساعات، ولكن بعض الدراسات وجدت 
+
+138
+00:09:57,540 --> 00:10:03,500
+أن فيه الـ Sperm وصل لأعلى جزء من قناة فالوب 
+
+139
+00:10:03,500 --> 00:10:07,860
+خلال دقائق بعد عملية الجماع فهذه نظرياً
+
+140
+00:10:07,860 --> 00:10:11,240
+okay، ولكن عملياً شيء آخر خلّيني أشوف كيف الـ 
+
+141
+00:10:11,240 --> 00:10:16,200
+phagocytosis بتشتغل على الـSperm خلال بقاءه في
+
+142
+00:10:16,200 --> 00:10:21,160
+منطقة الـcervical بعد 24 ساعة، إن لم يتخطى هذا
+
+143
+00:10:21,160 --> 00:10:29,230
+الحاجزنشوف إيش بيصير في هذه العملية الـ
+
+144
+00:10:29,230 --> 00:10:32,270
+sperm are foreign to a woman's body and are
+
+145
+00:10:32,270 --> 00:10:38,870
+treated as unwanted invaders. her
+
+146
+00:10:38,870 --> 00:10:44,190
+immune system is triggered to kill them once they
+
+147
+00:10:44,190 --> 00:10:48,050
+enter the cervix. they are in a labyrinth of dead
+
+148
+00:10:48,050 --> 00:10:51,510
+ends, perfect
+
+149
+00:10:51,510 --> 00:10:52,450
+for an ambush.
+
+150
+00:10:56,050 --> 00:11:02,650
+هذا البروسايت الورقاء
+
+151
+00:11:02,650 --> 00:11:09,850
+يهاجمون الحرارة من جميع الاتجاهات
+
+152
+00:11:09,850 --> 00:11:21,290
+عندما 
+
+153
+00:11:21,290 --> 00:11:26,000
+يصل أي ناجين للأمان من حفرة فولوبيا of the original
+
+154
+00:11:26,000 --> 00:11:34,640
+250 million that could be as few as 20 left. يعني
+
+155
+00:11:34,640 --> 00:11:38,860
+بيحكي ليه أن أول منطقة تعتبر أمنة لل sperm هي
+
+156
+00:11:38,860 --> 00:11:42,360
+الـferopian tube بعد ما يقطع ال sperm كل هذه
+
+157
+00:11:42,360 --> 00:11:47,840
+العوائق و المخاطر تقريبا بيصل 200 sperm, 300 sperm
+
+158
+00:11:47,840 --> 00:11:52,180
+ممكن يصل 10 وممكن يصل 20 وممكن يصل 50 هذا يعتمد
+
+159
+00:11:52,180 --> 00:11:57,670
+جديش PNDsperm في عملية ال ejaculation فبالتالي كل
+
+160
+00:11:57,670 --> 00:12:01,370
+مراحل التي يمر بها ال sperm مرورا من الفيجاينة
+
+161
+00:12:01,370 --> 00:12:05,630
+مدخل ال cervical, ال cervical هذه مراحل خطرة, أول
+
+162
+00:12:05,630 --> 00:12:09,530
+مرحلة تعتبر آمنة لل sperm هي ال fallopian tube
+
+163
+00:12:09,530 --> 00:12:16,690
+the fallopian tube صورة بتوضح الكلام اللي احنا حكيناه
+
+164
+00:12:16,690 --> 00:12:21,150
+تلاحظ في عندي مطيقة طبعا في عندي هنا واحد، اتنين
+
+165
+00:12:21,150 --> 00:12:25,280
+تلاتة، اربع، خمسة، ستة مناطق، وتحت كل منطقة فيها عدد ال
+
+166
+00:12:25,280 --> 00:12:28,860
+sperm اللي بيكون فيها فبالتالي أول منطقة sperm
+
+167
+00:12:28,860 --> 00:12:32,600
+dumped aside in the upper في جنة يعني المنطقة اللي
+
+168
+00:12:32,600 --> 00:12:36,080
+بيصير فيها عملية ال ejaculation بيكون فيها كل عدد
+
+169
+00:12:36,080 --> 00:12:39,640
+ال sperm قد يصل إلى عشرة والسبعة يعني بالملايين،
+
+170
+00:12:39,640 --> 00:12:44,000
+عشرة مليون، عشرين مليون، ثلاثين مليون يعتمد جداش
+
+171
+00:12:44,000 --> 00:12:50,700
+في عنده عينة المال يليها مباشرة ال cervic يدخل من
+
+172
+00:12:50,700 --> 00:12:55,390
+خلال ال cervicبسل في المرحلة ال base through
+
+173
+00:12:55,390 --> 00:13:01,730
+the cervical ال fast slow phase مليون تقريبا base
+
+174
+00:13:01,730 --> 00:13:07,590
+passage through المدخل الخاص بالرحم يوترست بسل
+
+175
+00:13:07,590 --> 00:13:11,890
+عندي كمان عشرة أو خمسة يعني بالعشر تلاف, عشرين ألف
+
+176
+00:13:11,890 --> 00:13:17,850
+ثلاثين ألف, مدخل القنابيب الخاصة بالفلو بين الطيوب
+
+177
+00:13:17,850 --> 00:13:22,250
+بسل عشرة أو أربعةالمرحلة التالتة هي عبارة عن
+
+178
+00:13:22,250 --> 00:13:26,050
+السباحة وصولا إلى منطقة الفنوبيا التيوبة التي يحدث
+
+179
+00:13:26,050 --> 00:13:29,550
+فيها التبويض التي يحدث فيها التبويض تسمى ال
+
+180
+00:13:29,550 --> 00:13:32,890
+fertilization. بصل .. بعدين بصل لمنطقة ال
+
+181
+00:13:32,890 --> 00:13:37,450
+fertilization بيكون مية إلى ألف يعني فقط البصل
+
+182
+00:13:37,450 --> 00:13:40,750
+للمنطقة اللي بيصير عندها ال fertilization تقريبا
+
+183
+00:13:40,750 --> 00:13:45,590
+يا إما بالمئات يا إما بالألف لا تتجاوز الألف شوف
+
+184
+00:13:45,590 --> 00:13:48,490
+كيف بيصير عندي reduction في ال count من عشر أقل
+
+185
+00:13:48,490 --> 00:13:53,770
+سبعة, العشرة أُس ثلاثة من عشرة أُس سبعة إلى عشرة أُس
+
+186
+00:13:53,770 --> 00:13:58,270
+ثلاثة يعني من عشرة مليون وخمسين مليون وسبعين مليون
+
+187
+00:13:58,270 --> 00:14:04,930
+إلى ألف فقط ده بيعمل طبعا there are two types of
+
+188
+00:14:04,930 --> 00:14:08,670
+sperm transportation through the cervix, الطريقة
+
+189
+00:14:08,670 --> 00:14:12,750
+الأولى هي ال fast أو ال first خلينا نسميها تتميز
+
+190
+00:14:12,750 --> 00:14:16,870
+هنا initial rapidly transport يعني عبارة عن عملية
+
+191
+00:14:16,870 --> 00:14:22,510
+نقلبطيئة سريعة جدا انه يشهر Rapidly Transport by
+
+192
+00:14:22,510 --> 00:14:26,510
+which some spermatozoa can arrive to the uterine
+
+193
+00:14:26,510 --> 00:14:30,330
+tube within five to ten minutes of ejaculation. هذا
+
+194
+00:14:30,330 --> 00:14:34,690
+الطريقة السريعة اللي من خلالها يستطيع ال sperm أن
+
+195
+00:14:34,690 --> 00:14:40,370
+يصل إلى القنوات الإباضة أو القنوات الفلو أو
+
+196
+00:14:40,370 --> 00:14:44,430
+القنوات المبيض خلال خمسة إلى عشرين دقيقة.
+
+197
+00:14:47,050 --> 00:14:50,570
+أما النوع الثاني من الحركة .. الحركة اللي بنسميها
+
+198
+00:14:50,570 --> 00:14:55,210
+slow phase of sperm transport وهذه طبعا بيصير فيها
+
+199
+00:14:55,210 --> 00:15:00,230
+swimming للـ sperm through the cervical mucus, معدل
+
+200
+00:15:00,230 --> 00:15:05,870
+انتقاله 2 إلى 3 ملي متر في الساعة, their storage on
+
+201
+00:15:05,870 --> 00:15:09,370
+the cervix and their final passage through the
+
+202
+00:15:09,370 --> 00:15:15,450
+cervical canal as much as 2 to 4 days later. مين
+
+203
+00:15:15,450 --> 00:15:18,710
+بيهمني الأولى ولا الثانية؟ كلاهما يدعم بعضهما الآخر،
+
+204
+00:15:18,710 --> 00:15:22,430
+ما أقدر أصل للثانية إذا أنا ما بدأت بالأولى، لأن
+
+205
+00:15:22,430 --> 00:15:25,890
+الأولى هي اللي هتخلي الـSperm يقطع الـcervical
+
+206
+00:15:25,890 --> 00:15:29,290
+ويقطع الـcervical canal, يقطع الـcervical ويقطع
+
+207
+00:15:29,290 --> 00:15:34,530
+الـcervical canal. once inside the fallopian tube
+
+208
+00:15:34,530 --> 00:15:38,230
+the spermatozoa influences isocretion of the tube 
+
+209
+00:15:38,230 --> 00:15:41,930
+to undergo the capacitation reaction.مجرد ما يصل
+
+210
+00:15:41,930 --> 00:15:45,650
+الـ sperm للـ fallopian tube بدا الـ sperm يتأثر
+
+211
+00:15:45,650 --> 00:15:49,130
+ببعض الإفرازات اللي بتفرزها الـ fallopian tube أو
+
+212
+00:15:49,130 --> 00:15:54,290
+الـ tubular بشكل عام هذه الـ tube بتفرز مواد بتخلي
+
+213
+00:15:54,290 --> 00:15:58,730
+ال sperm أكثر قدرة على التلقيح. there are two
+
+214
+00:15:58,730 --> 00:16:02,750
+critical events that occur during this period. إيش
+
+215
+00:16:02,750 --> 00:16:06,110
+بيصير خلال وجوده في الـ fallopian tube؟ شغل ثاني
+
+216
+00:16:06,110 --> 00:16:11,620
+الشغل الثاني الأولي تسمى capacitation وخلال عملية
+
+217
+00:16:11,620 --> 00:16:15,760
+الـcapacitation بيصير في عندي اكتساب ال sperm
+
+218
+00:16:15,760 --> 00:16:20,620
+لمقدرة عالية انه يخص بالبوابة من خلال أول حاجة
+
+219
+00:16:20,620 --> 00:16:23,980
+first phase of capacitation is remove the
+
+220
+00:16:23,980 --> 00:16:27,220
+cholesterol from the surface of sperm. عشان يصير
+
+221
+00:16:27,220 --> 00:16:29,900
+capacitation لازم ال sperm يمر بمرحلة ثانية
+
+222
+00:16:29,900 --> 00:16:33,700
+المرحلة الأولى ازالت ما يُعرف اسم ال cholesterol
+
+223
+00:16:33,700 --> 00:16:37,400
+droplets الموجودة في منطقة الـhead فبيخلي ال sperm
+
+224
+00:16:37,400 --> 00:16:41,140
+أخف.الكليسترول الـ droplets مهم جدًا في حماية الـ
+
+225
+00:16:41,140 --> 00:16:47,580
+head للـ sperm. الكليسترول تم تطبيقه على الـ sperm
+
+226
+00:16:47,580 --> 00:16:51,480
+head لتمنع الـ premature capacitation. إذا أضفت
+
+227
+00:16:51,480 --> 00:16:54,580
+الكليسترول الـ droplets حماية الـ sperm وبتمنع
+
+228
+00:16:54,580 --> 00:16:57,900
+الـcapacitation في غير وجهها تحت مسمى premature
+
+229
+00:16:57,900 --> 00:17:02,260
+capacitation should be prevented. the next step of
+
+230
+00:17:02,260 --> 00:17:05,160
+capacitation المرحلة الثانية من الـcapacitation
+
+231
+00:17:05,490 --> 00:17:08,690
+Removal of many of glycoprotein that were
+
+232
+00:17:08,690 --> 00:17:11,170
+hypothesized on the sperm head within the
+
+233
+00:17:11,170 --> 00:17:14,450
+epidermis. After their removal, the spermatozoa is
+
+234
+00:17:14,450 --> 00:17:18,490
+now a chemical core fertilized egg. فالكبستيشن
+
+235
+00:17:18,490 --> 00:17:22,290
+بيصير عندي شغل ثاني، الشغل الأول الكليسترول الدروبلتز
+
+236
+00:17:22,290 --> 00:17:26,930
+الموجودة في ال head يتم التخلص منها، الشغل الثاني
+
+237
+00:17:26,930 --> 00:17:31,170
+بيصير في عندي removing لكمية من ال glycoprotein
+
+238
+00:17:31,170 --> 00:17:34,840
+الموجودة في ال sperm of head.الشغلتين هدولة بيصير
+
+239
+00:17:34,840 --> 00:17:38,520
+الـ sperm قادر على تخصيب المواد الـ second
+
+240
+00:17:38,520 --> 00:17:41,500
+phenomena occur while the sperm are attached to
+
+241
+00:17:41,500 --> 00:17:46,240
+the distal tubule and lining that is hyperactivated،
+
+242
+00:17:46,240 --> 00:17:50,820
+hyperactivation. قُلت إن خلال الفلوبيا التيوب بتأثر
+
+243
+00:17:50,820 --> 00:17:54,660
+ال sperm بالـsecretion اللي بتفرزف فبيصير فيه حدثين
+
+244
+00:17:54,660 --> 00:17:58,680
+الحدث الأول سميته capacitation و بيصير فيه two
+
+245
+00:17:58,680 --> 00:18:02,610
+phases, والحدث الثاني بيسميه hyperactivation. برجع
+
+246
+00:18:02,610 --> 00:18:05,910
+بقول الـcapacitation بيصير عندي two phase أو two
+
+247
+00:18:05,910 --> 00:18:08,810
+stage, ال stage الأولى التخلص من ال cholesterol
+
+248
+00:18:08,810 --> 00:18:12,050
+droplets اللي موجودة في ال head فبالتالي بيصير أخف
+
+249
+00:18:12,050 --> 00:18:15,490
+ال phase الثانية بتخلص من بعض ال glycoprotein
+
+250
+00:18:15,490 --> 00:18:20,710
+فبيصير كده قادر يتحرك بصورة أسرع وقادر على
+
+251
+00:18:20,710 --> 00:18:23,370
+التخصيب. الحدث الثاني اللي بيصير في فعل ال
+
+252
+00:18:23,370 --> 00:18:27,170
+secretion هي ال hyper activation يعني زيادة حركته
+
+253
+00:18:27,170 --> 00:18:32,360
+زيادة قدرته على الاختراق. ال hyper activation هي
+
+254
+00:18:32,360 --> 00:18:37,580
+عبارة عن عملية يُقصد بها زيادة قدرة الـ sperm على
+
+255
+00:18:37,580 --> 00:18:43,420
+السباحة والحركة. بيصير كأنه بالضبط زي شنيور إيه
+
+256
+00:18:43,420 --> 00:18:47,160
+المقصود بالشنيور؟ هو عبارة عن الملف أو المجدح اللي
+
+257
+00:18:47,160 --> 00:18:52,880
+بيعمل عملية اختراق للحاقة أو لأي شيء صلب. فبصير
+
+258
+00:18:52,880 --> 00:18:55,820
+عندي .. هنشوفها كمان شوية في الفيديو كيف بيصير
+
+259
+00:18:55,820 --> 00:19:00,910
+hyper activation لل sperm, ويصيب الـ sperm قادر إنه
+
+260
+00:19:00,910 --> 00:19:05,330
+يخترق بالضبط زي البرريمة اللي بتعمل على الحفر في
+
+261
+00:19:05,330 --> 00:19:10,490
+الصخر من أجل الحصول والوصول إلى البترول بالضبط. and
+
+262
+00:19:10,490 --> 00:19:14,090
+allow the sperm to break free from their binding
+
+263
+00:19:14,090 --> 00:19:16,930
+with the tubule epithelium cell. هذا المقصود
+
+264
+00:19:16,930 --> 00:19:20,690
+بالـhyperactivity. طبعا الـhyperactivity assists the
+
+265
+00:19:20,690 --> 00:19:24,530
+sperm to penetration isthmus mucosa and
+
+266
+00:19:24,530 --> 00:19:29,110
+coronaradiata والـ Zoona Plucida التي تجمع الـ OVA
+
+267
+00:19:29,110 --> 00:19:32,770
+الـهيبر اكتيفيشن ليس بصير عبسا، لأ، بتساعد الـ
+
+268
+00:19:32,770 --> 00:19:35,670
+Desperme أن يخترق الـ Multilayer المحيط بالـ OVA
+
+269
+00:19:35,670 --> 00:19:38,970
+اللي قلنا هي عبارة عن الكيوميلاس من الخارج، يليها
+
+270
+00:19:38,970 --> 00:19:42,860
+من الداخل الـ coronal radiata اللي هي عبارة عن
+
+271
+00:19:42,860 --> 00:19:47,140
+ثلاثة لأربعة أو من اتنين لتلاتة layer ثم يليها الـ
+
+272
+00:19:47,140 --> 00:19:50,840
+zoonapelucida هذه كلها layer لازم يخترقها الـ
+
+273
+00:19:50,840 --> 00:19:54,300
+sperm عشان يخترقها بيحتاج إلى زيادة ال activity
+
+274
+00:19:54,300 --> 00:19:57,940
+تبعته تحت مصطلح بنسمي high bulb activation
+
+275
+00:19:57,940 --> 00:20:02,460
+fertilization of oocyte normally occur in the
+
+276
+00:20:02,460 --> 00:20:06,820
+umbellarium portion وهي عبارة عن ال upper third of
+
+277
+00:20:06,820 --> 00:20:12,050
+the uterine tube أو الوبيايتوبيعني وين بيصير عملية
+
+278
+00:20:12,050 --> 00:20:16,030
+ال fertilization بتصير في الثلث العلوي من
+
+279
+00:20:16,030 --> 00:20:21,170
+الفلوبيان التيوب. استيمتت
+
+280
+00:20:21,170 --> 00:20:25,910
+suggest that sperm return their functional in the 
+
+281
+00:20:25,910 --> 00:20:29,250
+female reproductive tract for approximately 37 to
+
+282
+00:20:29,250 --> 00:20:32,770
+80 hours  الـ sperm طالما وصل للفلوبيان التيوب
+
+283
+00:20:32,770 --> 00:20:36,910
+يستطيع أن يبقى أو فلنسميها بشكل عام الـ sperm
+
+284
+00:20:36,910 --> 00:20:41,120
+يستطيع أن يملك القدرة على الإخصاب ويملك الـ
+
+285
+00:20:41,120 --> 00:20:43,740
+functional كلمة الخاصة به وهو في الـ reproductive
+
+286
+00:20:43,740 --> 00:20:49,000
+tract الخاصة بالـ female لمدة ثلاث أيام لمدة ثلاث
+
+287
+00:20:49,000 --> 00:20:52,420
+أيام يعني لو صار intercourses  قبل .. قبل ال ..
+
+288
+00:20:52,420 --> 00:20:58,940
+ال .. الإباضة بيوم أو بعدها بيوم المفروض الـ sperm
+
+289
+00:20:58,940 --> 00:21:02,880
+يكون قادرًا على التخصيب لأن فترة حياة الـ sperm ثلاث
+
+290
+00:21:02,880 --> 00:21:06,580
+أيام بينما البويضة يوم واحد عشان كده يقول لنا أفضل
+
+291
+00:21:06,580 --> 00:21:11,310
+أوقات لحدوث الـ pregnancy هو حدوث الـ interfaces قبل
+
+292
+00:21:11,310 --> 00:21:16,350
+الإباضة بيوم أو يوم الإباضة خلينا نشوف الفيديو
+
+293
+00:21:16,350 --> 00:21:22,490
+المتعلق بموضوع الـ capacitation والـ hyperactivation
+
+294
+00:21:22,490 --> 00:21:27,230
+طبعًا 
+
+295
+00:21:27,230 --> 00:21:31,950
+هذا الفيديو بيتكلم عن أكثر من أمر الأمر الأول بيتكلم
+
+296
+00:21:31,950 --> 00:21:34,550
+عن الـ capacitation والـ hyperactivation في نهاية 
+
+297
+00:21:34,550 --> 00:21:39,250
+الفيديو بيتكلم كيف الكروموزومات الأبوية الخاصة بالـ
+
+298
+00:21:39,250 --> 00:21:42,050
+Male أو الخاصة بالـ Female بتندمج مع بعضها البعض و
+
+299
+00:21:42,050 --> 00:21:45,790
+بتكون زي الـ God وبتكوّن .. وبيتكلم عن الرحلة الصعبة
+
+300
+00:21:45,790 --> 00:21:48,650
+التي يمر بها الـ Spare في الـ Female
+
+301
+00:21:48,650 --> 00:21:52,730
+reproductive tract وما يقابله من مخاطر بداية 
+
+302
+00:21:52,730 --> 00:21:58,890
+بالـ Low pH مرورا بالـ cervical mucous مرورا بالـ 
+
+303
+00:21:58,890 --> 00:22:03,090
+immunological وصولا لأول منطقة آمنة وهي الـ
+
+304
+00:22:03,090 --> 00:22:09,810
+Fallopian tube أو الأنابيب الخاصة بالرحم
+
+305
+00:22:09,810 --> 00:22:17,410
+fertilization 
+
+306
+00:22:17,410 --> 00:22:20,290
+is the epic story of a single sperm facing
+
+307
+00:22:20,290 --> 00:22:23,670
+incredible odds to unite with an egg and form a
+
+308
+00:22:23,670 --> 00:22:26,870
+new human life it is the story of all of us
+
+309
+00:22:32,330 --> 00:22:35,730
+during sexual intercourse about 300 million sperm
+
+310
+00:22:35,730 --> 00:22:40,670
+enter the vagina soon 
+
+311
+00:22:40,670 --> 00:22:43,050
+afterward millions of them will either flow out of
+
+312
+00:22:43,050 --> 00:22:49,130
+the vagina or die in its acidic environment أول
+
+313
+00:22:49,130 --> 00:22:53,750
+خطر بيواجهه الـ sperm بعد ما كان عنده 300 مليون أنه 
+
+314
+00:22:53,750 --> 00:22:58,050
+كمية كبيرة جدًا منهم بتتوفى أو هتموت أو بتتدمّر بفعل الـ 
+
+315
+00:22:58,050 --> 00:23:01,150
+acidity الخاصة بالـ vagina الـ licensor that we
+
+316
+00:23:01,150 --> 00:23:03,690
+choose however many survive because of the
+
+317
+00:23:03,690 --> 00:23:05,850
+protective elements provided in the fluids 
+
+318
+00:23:05,850 --> 00:23:09,350
+surrounding them next the sperm must pass through
+
+319
+00:23:09,350 --> 00:23:13,670
+the cervix and opening into the uterus usually it
+
+320
+00:23:13,670 --> 00:23:16,910
+remains tightly closed but here the cervix is open
+
+321
+00:23:16,910 --> 00:23:20,990
+for a few days while the woman ovulates ينتقل إلى
+
+322
+00:23:20,990 --> 00:23:23,550
+الـ cervix من خلال الـ opening الخاص بالـ cervix اللي
+
+323
+00:23:23,550 --> 00:23:26,230
+هي دايمًا بتكون closed وما تصير لها opening إلا في 
+
+324
+00:23:26,230 --> 00:23:31,200
+مرحلة الإباضة الشمس تدخل من خلال ميوكس الشمسيكي
+
+325
+00:23:31,200 --> 00:23:34,880
+اللي كانت مدهشة إلى مستوى ماء أكثر لإيقاف المرحلة
+
+326
+00:23:34,880 --> 00:23:39,200
+الأسهل مرة داخل الشمس الشمسيكية الـ mucous الـ mucous
+
+327
+00:23:39,200 --> 00:23:44,240
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+328
+00:23:44,240 --> 00:23:44,500
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+329
+00:23:44,500 --> 00:23:44,560
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+330
+00:23:44,560 --> 00:23:44,660
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+331
+00:23:44,660 --> 00:23:56,720
+الميوكس الميوكس الميوكس الميوكس
+
+332
+00:23:56,720 --> 00:23:57,640
+الميوك
+
+333
+00:24:04,790 --> 00:24:08,630
+النظام اللي بيخلي السُّمْكِ يطفو غريبة تدمر أكثر من
+
+334
+00:24:08,630 --> 00:24:11,810
+الآلاف وأكثر منها تدمر أكثر منها تدمر أكثر منها
+
+335
+00:24:11,810 --> 00:24:16,790
+تدمر أكثر منها تدمر
+
+336
+00:24:16,790 --> 00:24:18,990
+أكثر منها تدمر أكثر منها تدمر أكثر منها تدمر أكثر
+
+337
+00:24:18,990 --> 00:24:19,410
+منها تدمر أكثر منها تدمر أكثر منها تدمر أكثر منها
+
+338
+00:24:19,410 --> 00:24:19,470
+تدمر أكثر منها تدمر أكثر منها تدمر أكثر منها تدمر
+
+339
+00:24:19,470 --> 00:24:26,570
+منها تدمر أكثر منها تدمر أكثر منها تدمر أكثر منها
+
+340
+00:24:26,570 --> 00:24:30,720
+تدمر Inside the fallopian tube, tiny cilia push the 
+
+341
+00:24:30,720 --> 00:24:34,500
+egg toward the uterus To continue, the sperm must
+
+342
+00:24:34,500 --> 00:24:37,920
+surge against this motion to reach the egg Some
+
+343
+00:24:37,920 --> 00:24:41,920
+sperm get trapped in the cilia and die During this
+
+344
+00:24:41,920 --> 00:24:44,380
+part of the journey, chemicals in the reproductive 
+
+345
+00:24:44,380 --> 00:24:46,820
+tract cause the membranes covering the heads of
+
+346
+00:24:46,820 --> 00:24:50,000
+the sperm to change حتى بيقول لي في بعض الدراسات 
+
+347
+00:24:50,000 --> 00:24:52,380
+بيقول لك السّيليا الموجودة في الـ fallopian tube اللي 
+
+348
+00:24:52,380 --> 00:24:56,420
+المفروض تساعد البويضة على النزول قد تقتل الـ Spare
+
+349
+00:24:56,420 --> 00:25:01,840
+من خلال تعثّر الـ Spare .. مش الـ Spare بتعمل كشبكة 
+
+350
+00:25:01,840 --> 00:25:05,020
+الـ Spare فبتعمل catching الـ Spare فبالتالي بيخفف
+
+351
+00:25:05,020 --> 00:25:08,540
+وبتعمل reduction في الـ Spare count أيضًا فبالتالي
+
+352
+00:25:08,540 --> 00:25:12,400
+أصبح الـ fallopian tube أيضًا البعض النظريات لا تعتبر
+
+353
+00:25:12,400 --> 00:25:16,720
+بيها آمنة okay تعتبر بيها آمنة من حيث الـ oxidative 
+
+354
+00:25:16,720 --> 00:25:21,290
+stress من حيث الـ pH من حيث مافيهش immune system،
+
+355
+00:25:21,290 --> 00:25:24,990
+من حيث مافيهش mucous أوكي مافيش مشكلة بسميها
+
+356
+00:25:24,990 --> 00:25:29,790
+safe environment، ولكن من حيث السّيليا، لا تعتبر 
+
+357
+00:25:29,790 --> 00:25:34,410
+safe As a result, the sperm become hydroactive,
+
+358
+00:25:34,870 --> 00:25:36,950
+swimming harder and faster toward their
+
+359
+00:25:36,950 --> 00:25:42,050
+destination At long last, the sperm reach the egg
+
+360
+00:25:45,390 --> 00:25:47,410
+فقط عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+361
+00:25:47,410 --> 00:25:49,070
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+362
+00:25:49,070 --> 00:25:50,130
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+363
+00:25:50,130 --> 00:25:53,770
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+364
+00:25:53,770 --> 00:25:53,850
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+365
+00:25:53,850 --> 00:25:54,150
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+366
+00:25:54,150 --> 00:25:55,470
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+367
+00:25:55,470 --> 00:25:59,490
+عشان عشان عشان عشان عشان
+
+368
+00:26:18,170 --> 00:26:20,650
+بالداخل من المنطقة الـ Pelucida يوجد مكان مليء 
+
+369
+00:26:20,650 --> 00:26:26,050
+بالطبقات المطلوبة فقط خارج إمكانيات البويضة الأول
+
+370
+00:26:26,050 --> 00:26:31,050
+ممكن أن يتواصل معها سوف تخصب البويضة بعد 
+
+371
+00:26:31,050 --> 00:26:35,790
+مهارة غير قوية وعن أعظم فرصة واحدة من البويضة تقع 
+
+372
+00:26:35,790 --> 00:26:40,530
+في إمكانيات البويضة خلال عدة دقائق من الوقت إمكانيات
+
+373
+00:26:40,530 --> 00:26:43,310
+البويضة الخارجية تتجمد وبويضة البويضة تدخل فيها
+
+374
+00:26:43,310 --> 00:26:48,120
+هذا الحدث يسبب في تغييرات في إمكانيات البويضة that 
+
+375
+00:26:48,120 --> 00:26:52,200
+prevent other sperm from attaching to it تحكي لي 
+
+376
+00:26:52,200 --> 00:26:55,740
+بعد اختراق أول Sperm للـ cell membrane الخاصة
+
+377
+00:26:55,740 --> 00:26:59,380
+بالـ Zona pellucida بيتم حجز هذا الـ sperm في الداخل
+
+378
+00:26:59,380 --> 00:27:04,120
+وتغيير التركيب الكيميائي الخاص بالـ Zona pellucida لمنع
+
+379
+00:27:04,120 --> 00:27:08,420
+دخول أي Sperm آخر عشان كده البويضة لا تلقح إلا بـ
+
+380
+00:27:08,420 --> 00:27:11,820
+single Sperm اللذي يخصب اللذي يخصب البويضة هو 
+
+381
+00:27:11,820 --> 00:27:17,500
+الأسرع والذي يصل بشكل أسرع فبالتالي لا يوجد بويضة 
+
+382
+00:27:17,500 --> 00:27:21,360
+تُلقّح بأكثر من الـ sperm لا يوجد بويضة تُلقّح
+
+383
+00:27:21,360 --> 00:27:24,940
+بأكثر من الـ sperm لعدة أسباب هنتكلم عنها أولها 
+
+384
+00:27:24,940 --> 00:27:28,520
+تغيير التركيب الكيميائي للـ receptor وخاص بيه على
+
+385
+00:27:28,520 --> 00:27:31,900
+سطح الـ zoonocyte خاص بالـ sperm Next, the egg
+
+386
+00:27:31,900 --> 00:27:34,500
+releases chemicals that push other sperm away from 
+
+387
+00:27:34,500 --> 00:27:37,400
+the egg and create an impenetrable fertilization 
+
+388
+00:27:37,400 --> 00:27:41,620
+membrane السبب الثاني أن البويضة نفسها بعد عملية
+
+389
+00:27:41,620 --> 00:27:44,550
+الـ fertilization تبدأ تفرز مواد كيميائية تعمل 
+
+390
+00:27:44,550 --> 00:27:48,430
+elimination أو طرد للـ sperm فتمنعه من عملية الـ
+
+391
+00:27:48,430 --> 00:27:51,390
+penetration as the reaction spreads outward the
+
+392
+00:27:51,390 --> 00:27:54,510
+zona pellucida hardens trapping any sperm unlucky
+
+393
+00:27:54,510 --> 00:27:59,750
+enough to be caught inside outside
+
+394
+00:27:59,750 --> 00:28:02,850
+the egg sperm are no longer able to attach to the 
+
+395
+00:28:02,850 --> 00:28:07,610
+zona pellucida الـ Zona pellucida أيضًا أصبحت very 
+
+396
+00:28:07,610 --> 00:28:10,790
+hard فبالتالي الـ sperm مش هيقدر يخترقها يعني ثلاث
+
+397
+00:28:10,790 --> 00:28:16,340
+أسباب تمنع تلقيح البويضة بأكثر من الـ sperm بمجرد 
+
+398
+00:28:16,340 --> 00:28:19,720
+دخول one sperm أو first sperm للبويضة البويضة
+
+399
+00:28:19,720 --> 00:28:23,660
+بتغيّر الـ receptor الخاصة بـ spermatozoon مولودة
+
+400
+00:28:23,660 --> 00:28:26,920
+على سطحها بتصير الـ Zona pellucida أكثر صلابة 
+
+401
+00:28:26,920 --> 00:28:29,840
+البويضة بتفرز بعض المواد الكيميائية اللي بتعمل 
+
+402
+00:28:29,840 --> 00:28:35,760
+elimination للـ sperm meanwhile inside the egg the 
+
+403
+00:28:35,760 --> 00:28:38,560
+tightly packed male genetic material spreads out 
+
+404
+00:28:40,790 --> 00:28:44,610
+تنظيم جديد يتطور حول المادة الجينية ويصنع الـ
+
+405
+00:28:44,610 --> 00:28:49,350
+Pronucleus الرجل في الداخل، المادة الجينية تتطور
+
+406
+00:28:49,350 --> 00:28:53,610
+مرة أخرى إلى 23 كروموزوم المادة الجينية الفتاة 
+
+407
+00:28:53,610 --> 00:28:56,710
+تتطور بمعالجة التعزيز من الزبدة مع الزبدة التي
+
+408
+00:28:56,710 --> 00:28:57,570
+تنتهي في المزيد من المزيد من المزيد من المزيد من 
+
+409
+00:28:57,570 --> 00:29:00,130
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+410
+00:29:00,130 --> 00:29:01,570
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+411
+00:29:01,570 --> 00:29:01,950
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+412
+00:29:01,950 --> 00:29:03,130
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+413
+00:29:03,130 --> 00:29:04,490
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+414
+00:29:04,490 --> 00:29:05,650
+المزيد
+
+415
+00:29:09,770 --> 00:29:14,250
+واتجهوا لبعضهم البعض النّوى النّوى
+
+416
+00:29:14,250 --> 00:29:17,710
+النّوى تتجمع مع بعضها البعض تكمل عملية التّنمية
+
+417
+00:29:17,710 --> 00:29:22,370
+في هذه اللّحظة تتجه موضوع كود جيني مميز للجنس
+
+418
+00:29:22,370 --> 00:29:25,910
+بسرعة تقوم بتحديد جمهورية، ورقم العيون، ورقم 
+
+419
+00:29:25,910 --> 00:29:29,910
+العيون، ومئات أخرى شخصية مختلفة. هذا الجلد 
+
+420
+00:29:29,910 --> 00:29:32,730
+الجنيني الجيني الجيني الجيني الجيني 
+
+421
+00:29:32,730 --> 00:29:33,210
+الانتاجي الانتاجي الانتاجي الانتاجي الانتاجي
+
+422
+00:29:33,210 --> 00:29:36,840
+الانتاجي الانتاجي And now the cilia in the
+
+423
+00:29:36,840 --> 00:29:39,900
+fallopian tube gently sweep the zygote toward the
+
+424
+00:29:39,900 --> 00:29:42,720
+uterus, where it will implant in the rich
+
+425
+00:29:42,720 --> 00:29:45,840
+uterine lining, growing and maturing for the next
+
+426
+00:29:45,840 --> 00:29:51,000
+nine months until ready for birth. هذه
+
+427
+00:29:51,000 --> 00:29:54,680
+عبارة عن رحلة تدخل ال sperm خلال ال female
+
+428
+00:29:54,680 --> 00:29:58,440
+reproductive tract وصولا إلى القنوات التي لها
+
+429
+00:29:58,440 --> 00:30:03,730
+علاقة بالمبيض أو القنوات fallopian tube التي لها
+
+430
+00:30:03,730 --> 00:30:09,170
+علاقة بعملية التبويض حيث تحدث في الثلث الأعلى من
+
+431
+00:30:09,170 --> 00:30:13,770
+fallopian tube عرفنا كيف تتم عملية نقل ال sperm
+
+432
+00:30:13,770 --> 00:30:18,930
+ما هي أهم ال actions اللي بتصير على ال sperm مجرد
+
+433
+00:30:18,930 --> 00:30:23,210
+وصوله لل fallopian tube تحت مصطلح capacitation و
+
+434
+00:30:23,210 --> 00:30:27,450
+hyperactivation تحت مصطلح capacitation و
+
+435
+00:30:27,450 --> 00:30:34,480
+hyperactivationهنتوقف عن هذا الحد في محاضرة اليوم،
+
+436
+00:30:34,480 --> 00:30:38,320
+على أمل أن نلتقي في محاضرة قادمة إن شاء الله،
+
+437
+00:30:38,320 --> 00:30:40,780
+دمتم بخير وفي حفظ الله 
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/04ZuGxhhn40_postprocess.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/04ZuGxhhn40_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..a85adf0e9d7a00a3e9ab6b1c94ce146f1892a31c
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/04ZuGxhhn40_postprocess.srt
@@ -0,0 +1,1748 @@
+1
+00:00:01,920 --> 00:00:05,800
+باسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,800 --> 00:00:11,640
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين أرجو من
+
+3
+00:00:11,640 --> 00:00:16,060
+الله الكريم أن تكونوا بخير جميعا استكمالا لما
+
+4
+00:00:16,060 --> 00:00:20,960
+تحدثنا فيه في المحاضرة السابقة حول عملية انتقال
+
+5
+00:00:20,960 --> 00:00:25,060
+النطف الذكيرية في الـ reproductive track الخاصة
+
+6
+00:00:25,060 --> 00:00:28,080
+بالمال والنطف الأنثوية في ال female reproductive
+
+7
+00:00:28,080 --> 00:00:34,240
+trackوقفنا في المحاضرة السابقة عند كلمة مهمة جدا
+
+8
+00:00:34,240 --> 00:00:38,520
+وهي عبارة عن Coagulum حكينا أن الـ Coagulum هي
+
+9
+00:00:38,520 --> 00:00:43,280
+عبارة عن تجلّقات بسيطة بفعل بروتينات موجودة في الـ
+
+10
+00:00:43,280 --> 00:00:47,780
+seminal fluid تعمل معامل ال network الشبكة التي
+
+11
+00:00:47,780 --> 00:00:52,580
+تحمل sperm بالداخل منالـ environment الخشنة أو
+
+12
+00:00:52,580 --> 00:00:55,700
+الغريبة أو الضارة الموجودة في ال reproductive
+
+13
+00:00:55,700 --> 00:01:00,020
+tract الخاصة بالفيميل وخاصة منطقة الفيجاينة بإضافة
+
+14
+00:01:00,020 --> 00:01:05,060
+إلى اختلاف الـ pH هذه الـ coagulant لازم يصير فيها
+
+15
+00:01:05,060 --> 00:01:11,400
+عملية dissolving أو losing عشان تتيح الفرصة لهذا
+
+16
+00:01:11,400 --> 00:01:16,700
+ال sperm ان يتحرك وصولا إلى منطقة ال cervicalبعد
+
+17
+00:01:16,700 --> 00:01:22,040
+حوالي 30 إلى 60 دقيقة من عملية خسارة الكواكولا
+
+18
+00:01:22,040 --> 00:01:27,360
+لبروستاتا لبروستاتا مخصصة انتجين وإنزايم بروتاليتك
+
+19
+00:01:27,360 --> 00:01:33,520
+سيكون مفرد ويخسر السمن الكواكولاتي في السمن
+
+20
+00:01:33,520 --> 00:01:37,740
+والتراث الفيجينالي الفلويد الاسبامي يبدأ بالمشاركة
+
+21
+00:01:37,740 --> 00:01:45,750
+بمجرد عملية .. بمجرد عمليةتحلل الكواجولام المحيط
+
+22
+00:01:45,750 --> 00:01:49,330
+بالـ sperm بتاع بعض الإنزيمات التي تكون موجودة في
+
+23
+00:01:49,330 --> 00:01:52,930
+الـ seminal fluid وأشهر بروستاتيك specific antigen
+
+24
+00:01:52,930 --> 00:01:55,330
+أو البروستاتيك specific antigen بالإضافة إلى الـ
+
+25
+00:01:55,330 --> 00:01:59,530
+proteolytic enzyme هذا يؤدي إلى تحلل الكواجولام،
+
+26
+00:01:59,530 --> 00:02:02,410
+تكسر البروتينات التي تعمل الـ coagulation حول الـ
+
+27
+00:02:02,410 --> 00:02:06,320
+spermفبالتالي الـ sperm بيكون حُب و بيبدأ يستطيع
+
+28
+00:02:06,320 --> 00:02:11,720
+الحركة والسباحة في اتجاه الفلوبيانيتيوب a critical
+
+29
+00:02:11,720 --> 00:02:15,380
+element in the sperm motility is the atayability
+
+30
+00:02:15,380 --> 00:02:19,580
+of fructose أهم شغل في ال sperm motility توفر كمية
+
+31
+00:02:19,580 --> 00:02:24,260
+كافية من الفرقتوز because of their leak of
+
+32
+00:02:24,260 --> 00:02:27,360
+cytoplasmic spermatozoa required an external
+
+33
+00:02:27,360 --> 00:02:32,680
+energy source بدون الفرقتوزما في قدرة على الحركة
+
+34
+00:02:32,680 --> 00:02:36,420
+علشان كده ممكن بعض الذكور يكون عنده الكون طبيعي
+
+35
+00:02:36,420 --> 00:02:41,420
+الحركة غير طبيعية بفعل شيء واحد وهو كمية ال
+
+36
+00:02:41,420 --> 00:02:44,440
+fractose الموجودة في السيمن والتي تستخدم كمصدر
+
+37
+00:02:44,440 --> 00:02:49,600
+أساسي للطاقة الخاصة بال sperm غير موجودة فلو تم
+
+38
+00:02:49,600 --> 00:02:55,280
+عمل فحص لل fractose test الذي يهمل بفعل بعضالمراكز
+
+39
+00:02:55,280 --> 00:03:00,340
+أو بعض المختبرات هيمكن تشخص الحالة المرضية يكون
+
+40
+00:03:00,340 --> 00:03:03,680
+علاجها بسيط جدا هي تناول فواكه تحتوى على الفركتوز
+
+41
+00:03:03,680 --> 00:03:06,880
+أو أخذ بعض المكملات الغذائية التي تحتوى على
+
+42
+00:03:06,880 --> 00:03:11,020
+الفركتوز usually for most cells spermatozoa have a
+
+43
+00:03:11,020 --> 00:03:13,560
+specific requirement for fructose rather than
+
+44
+00:03:13,560 --> 00:03:17,300
+glycose the more commonly utilized carbohydrate
+
+45
+00:03:17,300 --> 00:03:21,100
+energy source بيحكيلي أن ال spermatozoa أو ال
+
+46
+00:03:21,100 --> 00:03:25,690
+sperm كنطفة أو كخليةتختلف عن الخلايا الأخرى في
+
+47
+00:03:25,690 --> 00:03:29,910
+مصدرها للطاقة فمعظم الخلايا تستخدم الجليكوز كمصدر
+
+48
+00:03:29,910 --> 00:03:34,770
+للطاقة باستثناء الـ spermatozoa تستخدم الفراكتوز
+
+49
+00:03:34,770 --> 00:03:39,050
+وذلك لسببين حركتها السريعة جدا و التي تحتاج إلى
+
+50
+00:03:39,050 --> 00:03:43,330
+كمية هائلة من الطاقة بشكل مستمر فبالتالي احتراق
+
+51
+00:03:43,330 --> 00:03:48,000
+الفراكتوز لإنتاج الطاقة أسرع من احتراق الجليكوزإلى
+
+52
+00:03:48,000 --> 00:03:51,180
+بعض الإنزيمات المسؤولة عن احتراق الجليكوز زي
+
+53
+00:03:51,180 --> 00:03:54,240
+الـNexokinase وبالتالي اللي يمكن استخدامه بالطريقة
+
+54
+00:03:54,240 --> 00:03:59,400
+التي تستخدم فيها الفركتورز الـnexpires أو تاني
+
+55
+00:03:59,400 --> 00:04:05,080
+حاجز أو تاني خطر بجابل الـSperm إعبار عن منطقة
+
+56
+00:04:05,080 --> 00:04:07,700
+الـcervix الـcervical entrance
+
+57
+00:04:11,120 --> 00:04:14,980
+it is not only very small but it is blocked by
+
+58
+00:04:14,980 --> 00:04:19,260
+cervical mucus اتخلص ال sperm من ال pH الخاص
+
+59
+00:04:19,260 --> 00:04:24,400
+بالفاجينه وصل لأعتاب ال cervic يصطدم بخطر تاني وهو
+
+60
+00:04:24,400 --> 00:04:27,980
+عبارة عن مدخل ال cervic مدخل ال cervic فيه مشكلتين
+
+61
+00:04:27,980 --> 00:04:32,060
+المشكلة الأولى انه very close او very inner very
+
+62
+00:04:32,060 --> 00:04:36,840
+smallالشغل التاني انه مغلق بكمية كبيرة جدا من ال
+
+63
+00:04:36,840 --> 00:04:41,860
+ميوكاس تسمى cervical mucus طبعا during the most
+
+64
+00:04:41,860 --> 00:04:44,640
+time of menstrual cycle ال cervical mucus is very
+
+65
+00:04:44,640 --> 00:04:50,600
+high stick and very difficult to penetrate خلال
+
+66
+00:04:50,600 --> 00:04:54,160
+عملية menstrual cycle بنلاقي ال cervical مغلق
+
+67
+00:04:54,160 --> 00:04:57,960
+بكمية كبيرة جدا من الميوكاس الغليظة التي يصعب
+
+68
+00:04:57,960 --> 00:05:01,910
+اختراقهاوهذا نوع من أنواع الحماية، وهذا نوع من
+
+69
+00:05:01,910 --> 00:05:07,510
+أنواع الحماية حتى لو الـ Sperm صار Intercourses في
+
+70
+00:05:07,510 --> 00:05:11,730
+غير موضع الأبويد يعني القريب من ال menstrual cycle
+
+71
+00:05:11,730 --> 00:05:15,130
+أو ال period بتاعة ال menstrual cycle يصعب على ال
+
+72
+00:05:15,130 --> 00:05:20,670
+sperm اختراق هذه الكمية العقلة من ال mucusطب شو
+
+73
+00:05:20,670 --> 00:05:23,970
+اللي بيخلّي الميوكاس very stick أو very thick؟ هي
+
+74
+00:05:23,970 --> 00:05:27,290
+حاجة بتسميها cervical myosin هي نوع من أنواع
+
+75
+00:05:27,290 --> 00:05:30,550
+الجليكوبروتين وهو عبارة with high carbohydrate
+
+76
+00:05:30,550 --> 00:05:33,770
+composition الجليكوبروتين هو عبارة عن كمية كبيرة
+
+77
+00:05:33,770 --> 00:05:37,310
+جدا من الكربوهيدرات متصلة مع البروتين and soluble
+
+78
+00:05:37,310 --> 00:05:40,330
+compound cervical mucus is not ready penetration
+
+79
+00:05:40,330 --> 00:05:46,340
+يعني هذه ال cervical myosinتجعل الميوكاس الموجود
+
+80
+00:05:46,340 --> 00:05:49,860
+على مقدمة الـ cervic أو مدخل الـ cervical صاحب
+
+81
+00:05:49,860 --> 00:05:53,640
+اختراقه طب إيه اللي بيخلي الـ sperm قادر على
+
+82
+00:05:53,640 --> 00:05:56,820
+اختراقه؟ بيقول لك في أيام الطبوية اليوم 13 و اليوم
+
+83
+00:05:56,820 --> 00:06:01,800
+14 الهرمونات التي تفرز بفعل الـ ovary زي الـ
+
+84
+00:06:01,800 --> 00:06:05,300
+estrogenic hormone بعمل على تكوين الـ estrogenic
+
+85
+00:06:05,300 --> 00:06:10,140
+environment هذا اللي بتخلي الـ mucus very loose
+
+86
+00:06:10,140 --> 00:06:14,350
+بتعمل change في ال formationوفي الـ composition
+
+87
+00:06:14,350 --> 00:06:19,630
+وفي قوام ال cervical mucus فبصير بعد ما كان very
+
+88
+00:06:19,630 --> 00:06:24,170
+thick, very sticky, very thickness بصير watery سهل
+
+89
+00:06:24,170 --> 00:06:29,010
+ال penetration بفعل اسباب تصور متى؟ في لحظة أو
+
+90
+00:06:29,010 --> 00:06:32,270
+أيام الطبويل بصير إفراز كمية كبيرة جدا من
+
+91
+00:06:32,270 --> 00:06:36,370
+الاستروجين بيكون استروجينك environment بيغير طبيعة
+
+92
+00:06:36,370 --> 00:06:42,330
+ال cervical mucus بيخليه من stickyإلى واتري سهل ال
+
+93
+00:06:42,330 --> 00:06:47,830
+penetration بفعل ال sperm ال wire رقم تلاتة اللي
+
+94
+00:06:47,830 --> 00:06:51,710
+بيواجه ال sperm هو خلال عملية الانتقال بعد دخوله
+
+95
+00:06:51,710 --> 00:06:55,150
+ال cervic هي ال immunological شو يعني
+
+96
+00:06:55,150 --> 00:06:58,730
+immunological؟ يعني جهاز المناعة جهاز المناعة
+
+97
+00:06:58,730 --> 00:07:02,650
+بتعامل مع ال sperm كأنه foreign substance و طالما
+
+98
+00:07:02,650 --> 00:07:06,230
+هو foreign substance إذا بيحفظ جهاز المناعة فبيبدأ
+
+99
+00:07:06,230 --> 00:07:12,230
+جهاز المناعة يقتلالـ sperm بفعل الخلايا البلعمية
+
+100
+00:07:12,230 --> 00:07:17,690
+زي النيتروفيل و الـ Vagocyte الفاجينة و أيضًا الـ
+
+101
+00:07:17,690 --> 00:07:22,550
+cervic استخدمت استراتيجية إميونولوجية لإنقاذ الـ
+
+102
+00:07:22,550 --> 00:07:26,750
+pathogen من الانتقال و الانتقال إلى الـ cervical
+
+103
+00:07:26,750 --> 00:07:30,510
+للوصول إلى الجزء الأعلى من الـ female reproductive
+
+104
+00:07:30,510 --> 00:07:34,710
+tract و المقصود فيها الرحم و الـ fallopian tube
+
+105
+00:07:34,710 --> 00:07:37,490
+لأن لو ال pathogen وصل للرحم و الـ fallopian tube
+
+106
+00:07:37,680 --> 00:07:42,340
+يعني صار فيه إلتهاب، إلتهاب يعني ممكن يصير تقرحات،
+
+107
+00:07:42,340 --> 00:07:45,860
+تقرحات يعني ممكن يصير عندي adhesion، ligament
+
+108
+00:07:45,860 --> 00:07:49,240
+adhesion، endometriosis، يعني في الغالب
+
+109
+00:07:49,240 --> 00:07:54,640
+infertility طبعا من أشهر الخلايا التي تساهم في هذه
+
+110
+00:07:54,640 --> 00:07:57,580
+الحماية هي عبارة عن الـ Neutrophil و ال macro و ال
+
+111
+00:07:57,580 --> 00:08:01,000
+macrophage بالإضافة إلى بعض الـ monoglobulin like
+
+112
+00:08:01,000 --> 00:08:06,080
+IgAand IGG وال IGG بالذات لإنه very small في ال
+
+113
+00:08:06,080 --> 00:08:10,920
+size وال IGA لإنه ممكن يتواجد في ال secretion
+
+114
+00:08:10,920 --> 00:08:16,120
+فبالتالي لم يتم اختيار ال IGA وال IGG عبثا ولكن ال
+
+115
+00:08:16,120 --> 00:08:19,340
+IGG بسبب صغر حجمه فبالتالي ممكن يعمل filtration
+
+116
+00:08:19,340 --> 00:08:23,500
+لأى مكان وال IGA لإنه سهل تواجده في ال secretion
+
+117
+00:08:23,500 --> 00:08:28,080
+فهيكلامه بيشتغل ضد أي foreign substance بيمنعه من
+
+118
+00:08:28,080 --> 00:08:34,520
+ال invasionالسيرماتوزوه أيضًا تحفز بعض هذه
+
+119
+00:08:34,520 --> 00:08:40,200
+الدفاعات لإيقاف أكتر منها في ترانزيانها إلى داخل
+
+120
+00:08:40,200 --> 00:08:45,060
+السيرفيكال رغم أن السيرماتوزوه تستطيع أن تحفز أحد
+
+121
+00:08:45,060 --> 00:08:49,260
+هذه الـ buyers الخاصة بالإيميونولوجيكال إلى أنها
+
+122
+00:08:49,260 --> 00:08:52,600
+تستطيع أن تتغلب عليهم وإلا كيف تصير عملية ال
+
+123
+00:08:52,600 --> 00:08:57,460
+fertilization بعد 24 ساعة من بقاء السيرم في منطقة
+
+124
+00:08:57,460 --> 00:09:01,290
+السيرفيكالبتبدأ ال Vagocyte تشتغل المتمثلة في الـ
+
+125
+00:09:01,290 --> 00:09:06,810
+Neutrophil و Macrophage بتعمل Vagocytosis و
+
+126
+00:09:06,810 --> 00:09:12,050
+Engulfing للـ spermatozoa فبتعمل reduction في عدد
+
+127
+00:09:12,050 --> 00:09:16,030
+ال spermatozoa التي قد تصل إلى ال Oocyte فبدل ما
+
+128
+00:09:16,030 --> 00:09:20,570
+يصل مليون بيصل 200 ألف، 300 ألف، 400 ألف، 900 ألف
+
+129
+00:09:20,570 --> 00:09:23,970
+يعني بصلا يطلع عندي 50 مليون، 20 مليون، 30 مليون،
+
+130
+00:09:23,970 --> 00:09:28,140
+300 مليونبصل لكمية بالألاف فقط لغير واحد منهم
+
+131
+00:09:28,140 --> 00:09:32,620
+يستطيع تلقيه القوائد الـ swimming speed of the
+
+132
+00:09:32,620 --> 00:09:36,800
+human sperm in the fluid is approximately five
+
+133
+00:09:36,800 --> 00:09:41,220
+millimeters per minute لو أنا قرنت حركة ال sperm
+
+134
+00:09:41,220 --> 00:09:45,180
+في الوضع الطبيعي بناجي سرعة ال sperm تصل خمسة ملي
+
+135
+00:09:45,180 --> 00:09:48,800
+متر في الدقيقة يعني بالوضع النظري المعقول و
+
+136
+00:09:48,800 --> 00:09:52,540
+الحسابات المعقولة عشان يصل للمنطقة المطلوبة منه
+
+137
+00:09:52,540 --> 00:09:57,540
+بحتاج إلى minuteأو hours، ولكن بعض الدراسات وجدت
+
+138
+00:09:57,540 --> 00:10:03,500
+أن فيه الـSperm وصل للأعلى جزء من الفلوبيا نتيوب
+
+139
+00:10:03,500 --> 00:10:07,860
+خلال دقائق بعد عملية الـintercourses فهذه نظرياً
+
+140
+00:10:07,860 --> 00:10:11,240
+okay، ولكن عملياً شيء آخر خلّيني أشوف كيف ال
+
+141
+00:10:11,240 --> 00:10:16,200
+vagocytosis بتشتغل على الـSperm خلال بقاءه في
+
+142
+00:10:16,200 --> 00:10:21,160
+منطقة الـcervical بعد 24 ساعة، إن لم يتخطى هذا
+
+143
+00:10:21,160 --> 00:10:29,230
+الحاجزنشوف إيش بيصير في هذه العملية الـ
+
+144
+00:10:29,230 --> 00:10:32,270
+sperm are foreign to a woman's body and are
+
+145
+00:10:32,270 --> 00:10:38,870
+treated as unwanted invaders her
+
+146
+00:10:38,870 --> 00:10:44,190
+immune system is triggered to kill them once they
+
+147
+00:10:44,190 --> 00:10:48,050
+enter the cervix they are in a labyrinth of dead
+
+148
+00:10:48,050 --> 00:10:51,510
+ends perfect
+
+149
+00:10:51,510 --> 00:10:52,450
+for an ambush
+
+150
+00:10:56,050 --> 00:11:02,650
+هذا البروسايت الورقاء
+
+151
+00:11:02,650 --> 00:11:09,850
+يهاجمون الحرارة من جميع الاتجاهات
+
+152
+00:11:09,850 --> 00:11:21,290
+عندما
+
+153
+00:11:21,290 --> 00:11:26,000
+يصل أي ناجين للأمان من حفرة فولوبياof the original
+
+154
+00:11:26,000 --> 00:11:34,640
+250 million that could be as few as 20 left يعني
+
+155
+00:11:34,640 --> 00:11:38,860
+بيحكي ليه أن أول منطقة تعتبر أمنة لل sperm هي
+
+156
+00:11:38,860 --> 00:11:42,360
+الferopian tube بعد ما يقطع ال sperm كل هذه
+
+157
+00:11:42,360 --> 00:11:47,840
+العوائق و المخاطر تقريبا بيصل 200 sperm 300 sperm
+
+158
+00:11:47,840 --> 00:11:52,180
+ممكن يصل 10 و ممكن يصل 20 و ممكن يصل 50 هذا يعتمد
+
+159
+00:11:52,180 --> 00:11:57,670
+جديش PNDSperm في عملية ال ejaculation فبالتالي كل
+
+160
+00:11:57,670 --> 00:12:01,370
+مراحل التي يمر بها ال sperm مرورا من الفيجاينة
+
+161
+00:12:01,370 --> 00:12:05,630
+مدخل ال cervical ال cervical هذه مراحل خطرة أول
+
+162
+00:12:05,630 --> 00:12:09,530
+مرحلة تعتبر آمنة لل sperm هي ال fallopian tube
+
+163
+00:12:09,530 --> 00:12:16,690
+fallopian tube صورة بتوضح الكلام اللي احنا حكيناه
+
+164
+00:12:16,690 --> 00:12:21,150
+تلاحظ في عندي مطيقة طبعا في عندي هنا واحد اتنين
+
+165
+00:12:21,150 --> 00:12:25,280
+تلاتة اربع خمسة ستة مناطقوتحت كل منطقة فيها عدد ال
+
+166
+00:12:25,280 --> 00:12:28,860
+sperm اللي بيكون فيها فبالتالي أول منطقة sperm
+
+167
+00:12:28,860 --> 00:12:32,600
+dump aside in the upper في جنة يعني المنطقة اللي
+
+168
+00:12:32,600 --> 00:12:36,080
+بيصير فيها عملية ال ejaculation بيكون فيها كل عدد
+
+169
+00:12:36,080 --> 00:12:39,640
+ال sperm قد يصل إلى عشرة والسبعة يعني بالملايين،
+
+170
+00:12:39,640 --> 00:12:44,000
+عشرة مليون، اشرين مليون، تلاتين مليون يعتمد جداش
+
+171
+00:12:44,000 --> 00:12:50,700
+في عنده عينة المال يليها مباشرة ال cervic يدخل من
+
+172
+00:12:50,700 --> 00:12:55,390
+خلال ال cervicبسل في المرحلة ال base through
+
+173
+00:12:55,390 --> 00:13:01,730
+cervical ال fast slow phase مليون تقريبا base
+
+174
+00:13:01,730 --> 00:13:07,590
+passage through المدخل الخاص بالرحم يوترست بسل
+
+175
+00:13:07,590 --> 00:13:11,890
+عندي كمان عشرة أوس خمسة يعني بالعشر تلاف عشرين ألف
+
+176
+00:13:11,890 --> 00:13:17,850
+تلاتين ألف مدخل القنابيب الخاصة بالفلو بين الطيوب
+
+177
+00:13:17,850 --> 00:13:22,250
+بسل عشرة أوس أربعةالمرحلة التالتة هي عبارة عن
+
+178
+00:13:22,250 --> 00:13:26,050
+السباحة وصولا إلى منطقة الفنوبيا التيوبة التي يحدث
+
+179
+00:13:26,050 --> 00:13:29,550
+فيها التبويض التي يحدث فيها التبويض تسمى ال
+
+180
+00:13:29,550 --> 00:13:32,890
+fertilization بصل .. بعدين بصل لمنطقة ال
+
+181
+00:13:32,890 --> 00:13:37,450
+fertilization بيكون مية إلى ألف يعني فقط البصل
+
+182
+00:13:37,450 --> 00:13:40,750
+للمنطقة اللي بيصير عندها ال fertilization تقريبا
+
+183
+00:13:40,750 --> 00:13:45,590
+يا إما بالمئات يا إما بالألف لا تتجاوز الألف شوف
+
+184
+00:13:45,590 --> 00:13:48,490
+كيف بيصير عندي reduction في ال count من عشر أقل
+
+185
+00:13:48,490 --> 00:13:53,770
+سبعةالعشرة أُس ثلاثة من عشرة أُس سبعة إلى عشرة أُس
+
+186
+00:13:53,770 --> 00:13:58,270
+ثلاثة يعني من عشرة مليون وخمسين مليون وسبعين مليون
+
+187
+00:13:58,270 --> 00:14:04,930
+إلى ألف فقط ده بيعمل طبعا there are two type of
+
+188
+00:14:04,930 --> 00:14:08,670
+sperm transportation through the cervix الطريقة
+
+189
+00:14:08,670 --> 00:14:12,750
+الأولى هي ال fast أو ال first خلينا نسميها تتميز
+
+190
+00:14:12,750 --> 00:14:16,870
+هنا initial rapidly transport يعني عبارة عن عملية
+
+191
+00:14:16,870 --> 00:14:22,510
+نقلبطيئة سريعة جدا انه يشهر Rapidly Transport by
+
+192
+00:14:22,510 --> 00:14:26,510
+which some spermatozoa can arrive to the uterine
+
+193
+00:14:26,510 --> 00:14:30,330
+tube within five to ten minutes of ejaculation هذا
+
+194
+00:14:30,330 --> 00:14:34,690
+الطريقة السريعة اللي من خلالها يستطيع ال sperm أن
+
+195
+00:14:34,690 --> 00:14:40,370
+يصل إلى القنوات الإباضة أو القنوات الفلو أو
+
+196
+00:14:40,370 --> 00:14:44,430
+القنوات المبيض خلال خمسة إلى عشرين دقيقة
+
+197
+00:14:47,050 --> 00:14:50,570
+أما النوع التاني من الحركة .. الحركة اللي بنسميها
+
+198
+00:14:50,570 --> 00:14:55,210
+slow phase of sperm transport وهذه طبعا بيصير فيها
+
+199
+00:14:55,210 --> 00:15:00,230
+swimming للـ sperm through the cervical mucus معدل
+
+200
+00:15:00,230 --> 00:15:05,870
+انتقاله 2 إلى 3 ملي متر في الساعة their storage on
+
+201
+00:15:05,870 --> 00:15:09,370
+the cervical and their final passage through the
+
+202
+00:15:09,370 --> 00:15:15,450
+cervical canal as much as 2 to 4 days laterمين
+
+203
+00:15:15,450 --> 00:15:18,710
+بيهمني الأولى ولا التانية؟ كلاهم يدعم بعضهم الآخر،
+
+204
+00:15:18,710 --> 00:15:22,430
+ماقدر أصل للتانية إذا أنا مابدأتش بالأولى، لأن
+
+205
+00:15:22,430 --> 00:15:25,890
+الأولى هي اللي هتخلي الـSperm يقطع الـcervical
+
+206
+00:15:25,890 --> 00:15:29,290
+ويقطع الـcervical canal يقطع الـcervical ويقطع
+
+207
+00:15:29,290 --> 00:15:34,530
+الـcervical canal once inside the fallopian tube
+
+208
+00:15:34,530 --> 00:15:38,230
+الـspermatozoa influences isocretion of the tube
+
+209
+00:15:38,230 --> 00:15:41,930
+to undergo the capacitation reactionمجرد ما يصل
+
+210
+00:15:41,930 --> 00:15:45,650
+الـ sperm للـ fallopian tube بدا الـ sperm يتأثر
+
+211
+00:15:45,650 --> 00:15:49,130
+ببعض الإفرازات اللي بتفرزها الـ fallopian tube أو
+
+212
+00:15:49,130 --> 00:15:54,290
+الـ tubular بشكل عام هذه الـ tube بتفرز مواد بتخلي
+
+213
+00:15:54,290 --> 00:15:58,730
+ال sperm أكثر قدرة على التلقيح there are two
+
+214
+00:15:58,730 --> 00:16:02,750
+critical events that occur during this period إيش
+
+215
+00:16:02,750 --> 00:16:06,110
+بيصير خلال وجوده في الـ fallopian tube؟ شغل تاني
+
+216
+00:16:06,110 --> 00:16:11,620
+الشغل التاني الأولى تسمى capacitationوخلال عملية
+
+217
+00:16:11,620 --> 00:16:15,760
+الcapacitation بيصير في عندي اكتساب ال sperm
+
+218
+00:16:15,760 --> 00:16:20,620
+لمقدرة عالية انه يخص بالبوابة من خلال أول حاجة
+
+219
+00:16:20,620 --> 00:16:23,980
+first phase of capacitation is remove the
+
+220
+00:16:23,980 --> 00:16:27,220
+cholesterol from the surface of sperm عشان يصير
+
+221
+00:16:27,220 --> 00:16:29,900
+capacitation لازم ال sperm يمر بمرحلة تانية
+
+222
+00:16:29,900 --> 00:16:33,700
+المرحلة الأولى ازالت ما يُعرف اسم ال cholesterol
+
+223
+00:16:33,700 --> 00:16:37,400
+droplets الموجودة في منطقة الhead فبيخلي ال sperm
+
+224
+00:16:37,400 --> 00:16:41,140
+أخفالكليسترول الـ droplets مهم جدًا في حماية الـ
+
+225
+00:16:41,140 --> 00:16:47,580
+head للـ sperm الكليسترول تم تطبيقه على الـ sperm
+
+226
+00:16:47,580 --> 00:16:51,480
+head لتمنع الـ premature capacitation إذا أضفت
+
+227
+00:16:51,480 --> 00:16:54,580
+الكليسترول الـ droplets حماية الـ sperm وبتمنع
+
+228
+00:16:54,580 --> 00:16:57,900
+الcapacitation في غير وجهها تحت مسمى premature
+
+229
+00:16:57,900 --> 00:17:02,260
+capacitation should be prevented the next step of
+
+230
+00:17:02,260 --> 00:17:05,160
+capacitation المرحلة التانية من الcapacitation
+
+231
+00:17:05,490 --> 00:17:08,690
+Remove of many of glycoprotein that were
+
+232
+00:17:08,690 --> 00:17:11,170
+hypothesized on the sperm head within the
+
+233
+00:17:11,170 --> 00:17:14,450
+epidermis. After their removal, the spermatozoa is
+
+234
+00:17:14,450 --> 00:17:18,490
+now a chemical core fertilized egg فالكبستيشن
+
+235
+00:17:18,490 --> 00:17:22,290
+بيصير عندي شغل تاني الشغل الأولى كلسترول الدروبلتز
+
+236
+00:17:22,290 --> 00:17:26,930
+الموجودة في ال head يتم التخلص منها الشغل التانى
+
+237
+00:17:26,930 --> 00:17:31,170
+بيصير في عندي removing لكمية من ال glycoprotein
+
+238
+00:17:31,170 --> 00:17:34,840
+الموجودة في ال sperm of headالشغلتين هدولة بيصير
+
+239
+00:17:34,840 --> 00:17:38,520
+الـ sperm قادر على تخصيب المواد الـ second
+
+240
+00:17:38,520 --> 00:17:41,500
+phenomena occur while the sperm are attached to
+
+241
+00:17:41,500 --> 00:17:46,240
+the distal tubule و lining that is hyperactivated،
+
+242
+00:17:46,240 --> 00:17:50,820
+hyperactivation قُلت إن خلال الفلوبيا التيوب بتأثر
+
+243
+00:17:50,820 --> 00:17:54,660
+ال sperm بالsecretion اللي بتفرزف فبيصير فيه حدثين
+
+244
+00:17:54,660 --> 00:17:58,680
+الحدث الأول سميته capacitation و بيصير فيه two
+
+245
+00:17:58,680 --> 00:18:02,610
+phases و الحدث التاني بيسميه hyperactivationبرجع
+
+246
+00:18:02,610 --> 00:18:05,910
+بقول الcapacitation بيصير عندي two phase أو two
+
+247
+00:18:05,910 --> 00:18:08,810
+stage ال stage الأولى التخلص من ال cholesterol
+
+248
+00:18:08,810 --> 00:18:12,050
+droplets اللي موجودة في ال head فبالتالي بيصير أخف
+
+249
+00:18:12,050 --> 00:18:15,490
+ال phase التاني بتخلص من بعض ال glycoprotein
+
+250
+00:18:15,490 --> 00:18:20,710
+فبيصير كده قادر يتحرك بصورة أسرع و قادر على
+
+251
+00:18:20,710 --> 00:18:23,370
+التخصيب الحدث التاني اللي بيصير في فعل ال
+
+252
+00:18:23,370 --> 00:18:27,170
+secretion هي ال hyper activation يعني زيادة حركته
+
+253
+00:18:27,170 --> 00:18:32,360
+زيادة قدرته على الاختراق ال hyper activationهي
+
+254
+00:18:32,360 --> 00:18:37,580
+عبارة عن عملية يُقصد بها زيادة قدرة الـ sperm على
+
+255
+00:18:37,580 --> 00:18:43,420
+السباحة والحركة بيصير كأنه بالظبط زي شنيور إيه
+
+256
+00:18:43,420 --> 00:18:47,160
+المقصود بالشنيور؟ هو عبارة عن الملف أو المجدح اللي
+
+257
+00:18:47,160 --> 00:18:52,880
+بيعمل عملية اختراق للحاقة أو لأي شيء صلي فبصير
+
+258
+00:18:52,880 --> 00:18:55,820
+عندي .. هنشوفها كمان شوية في الفيديو كيف بيصير
+
+259
+00:18:55,820 --> 00:19:00,910
+hyper activation لل spermويصيب الـ sperm قادر إنه
+
+260
+00:19:00,910 --> 00:19:05,330
+يخترق بالضبط زي البرريمة اللي بتعمل على الحفر في
+
+261
+00:19:05,330 --> 00:19:10,490
+الصخر من أجل الحصول والوصول إلى البترول بالضبط and
+
+262
+00:19:10,490 --> 00:19:14,090
+allow the sperm to break free from their binding
+
+263
+00:19:14,090 --> 00:19:16,930
+with the tubule epithelium cell هذا المقصود
+
+264
+00:19:16,930 --> 00:19:20,690
+بالhyperactivity طبعا الhyperactivity assists the
+
+265
+00:19:20,690 --> 00:19:24,530
+sperm to penetration isthmus mucosa and
+
+266
+00:19:24,530 --> 00:19:29,110
+coronaradiataو الـ Zoona Plucida التي تجمع الـ OVA
+
+267
+00:19:29,110 --> 00:19:32,770
+الهيبر اكتيفيشن ليس بصير عبسا، لأ، بتساعد الـ
+
+268
+00:19:32,770 --> 00:19:35,670
+Desperme أن يخلق الـ Multilayer المحيط بالـ OVA
+
+269
+00:19:35,670 --> 00:19:38,970
+اللي قلنا هي عبارة عن الكيوميلاس من الخارج، يليها
+
+270
+00:19:38,970 --> 00:19:42,860
+من الداخلالـ coronal radiata اللي هي عبارة عن
+
+271
+00:19:42,860 --> 00:19:47,140
+تلاتة لأربعة أو من اتنين لتلاتة layer ثم يليها الـ
+
+272
+00:19:47,140 --> 00:19:50,840
+zoonopelucida هذه كلها layer لازم يخترقها الـ
+
+273
+00:19:50,840 --> 00:19:54,300
+sperm عشان يخترقها بيحتاج إلى زيادة ال activity
+
+274
+00:19:54,300 --> 00:19:57,940
+تبعته تحت مصطلح بنسمي high bulb activation
+
+275
+00:19:57,940 --> 00:20:02,460
+fertilization of oocyte normally occur in the
+
+276
+00:20:02,460 --> 00:20:06,820
+umbellarium portion وهي عبارة عن ال upper third of
+
+277
+00:20:06,820 --> 00:20:12,050
+the uterine tube أو الوبيايتوبيعني وين بيصير عملية
+
+278
+00:20:12,050 --> 00:20:16,030
+ال fertilization بتصير في الثلث العلوي من
+
+279
+00:20:16,030 --> 00:20:21,170
+الفلوبيان التيوب استيمتت
+
+280
+00:20:21,170 --> 00:20:25,910
+suggest that sperm return their functional in the
+
+281
+00:20:25,910 --> 00:20:29,250
+female reproductive tract for approximately 37 to
+
+282
+00:20:29,250 --> 00:20:32,770
+80 hours ال sperm طالما وصل للفلوبيان التيوب
+
+283
+00:20:32,770 --> 00:20:36,910
+يستطيع أن يبقى أو فلينا نسميها بشكل عام ال sperm
+
+284
+00:20:36,910 --> 00:20:41,120
+يستطيع أن يملك القدرة على الإخصادويملك ال
+
+285
+00:20:41,120 --> 00:20:43,740
+functional كلمة الخاصة فيه وهو في ال reproductive
+
+286
+00:20:43,740 --> 00:20:49,000
+track الخاصة بال female لمدة تلت أيام لمدة تلت
+
+287
+00:20:49,000 --> 00:20:52,420
+أيام يعني لو صار inter courses جابل .. جابل ال ..
+
+288
+00:20:52,420 --> 00:20:58,940
+ال .. الإبادة بيوم أو بعدها بيوم المفروض ال sperm
+
+289
+00:20:58,940 --> 00:21:02,880
+يكون قادر على التخسيب لأن فترة حياة ال sperm تلت
+
+290
+00:21:02,880 --> 00:21:06,580
+أيام بينما البوايضة يوم واحد عشان كده يقولنا أفضل
+
+291
+00:21:06,580 --> 00:21:11,310
+أوقاتبحدوث ال pregnancy هو حدوث ال interfaces قبل
+
+292
+00:21:11,310 --> 00:21:16,350
+الإبادة بيوم أو يوم الإبادة خلّينا نشوف الفيديو
+
+293
+00:21:16,350 --> 00:21:22,490
+المتعلق بموضوع الcapacitation و الhyperactivation
+
+294
+00:21:22,490 --> 00:21:27,230
+طبعا
+
+295
+00:21:27,230 --> 00:21:31,950
+هذا الفيديو بتكلم عن أكثر من أمر الأمر الأول بتكلم
+
+296
+00:21:31,950 --> 00:21:34,550
+عن الcapacitation و الhyperactivation في نهاية
+
+297
+00:21:34,550 --> 00:21:39,250
+الفيديوبتكلم كيف الكرموزومات الأبوية الخاصة بالـ
+
+298
+00:21:39,250 --> 00:21:42,050
+Male أو الخاصة بال Female بتدمجوا مع بعض البعض و
+
+299
+00:21:42,050 --> 00:21:45,790
+تكون زي God و بتكوّى .. و بتكلم عن الرحلة الصعبة
+
+300
+00:21:45,790 --> 00:21:48,650
+اللتي أمور بيها الـ Spare في الـ Female
+
+301
+00:21:48,650 --> 00:21:52,730
+reproductive tract و ما يقابلها من مخاطر بداية
+
+302
+00:21:52,730 --> 00:21:58,890
+بالـ Low pH مرورا بالـ cervical mucous مرورا بالـ
+
+303
+00:21:58,890 --> 00:22:03,090
+immunological وصولا إلى أول منطقة آمنة وهي ال
+
+304
+00:22:03,090 --> 00:22:09,810
+Fallopian tubeأو الأنابيب خاصة بالرحمة
+
+305
+00:22:09,810 --> 00:22:17,410
+fertilization
+
+306
+00:22:17,410 --> 00:22:20,290
+is the epic story of a single sperm facing
+
+307
+00:22:20,290 --> 00:22:23,670
+incredible odds to unite with an egg and form a
+
+308
+00:22:23,670 --> 00:22:26,870
+new human life it is the story of all of us
+
+309
+00:22:32,330 --> 00:22:35,730
+دuring sexual intercourse about 300 million sperm
+
+310
+00:22:35,730 --> 00:22:40,670
+enter the vagina soon
+
+311
+00:22:40,670 --> 00:22:43,050
+afterward millions of them will either flow out of
+
+312
+00:22:43,050 --> 00:22:49,130
+the vagina or die in its acidic environment أول
+
+313
+00:22:49,130 --> 00:22:53,750
+خطر بواجهه ال spirit بعد ما كان عنده 300 مليون أنه
+
+314
+00:22:53,750 --> 00:22:58,050
+كمية كبيرة جدا منهم بتوفى أو هموت أو بتدمر بفعل ال
+
+315
+00:22:58,050 --> 00:23:01,150
+acidity الخاصة بالفاجينةالـ licensor that we
+
+316
+00:23:01,150 --> 00:23:03,690
+choose however many survive because of the
+
+317
+00:23:03,690 --> 00:23:05,850
+protective elements provided in the fluids
+
+318
+00:23:05,850 --> 00:23:09,350
+surrounding them next the sperm must pass through
+
+319
+00:23:09,350 --> 00:23:13,670
+the cervix and opening into the uterus usually it
+
+320
+00:23:13,670 --> 00:23:16,910
+remains tightly closed but here the cervix is open
+
+321
+00:23:16,910 --> 00:23:20,990
+for a few days while the woman ovulates ينتقل إلى
+
+322
+00:23:20,990 --> 00:23:23,550
+ال cervix من خلال ال opening الخاص بالcervix اللي
+
+323
+00:23:23,550 --> 00:23:26,230
+هي دايما بتكون closed وماتصير لها opening إلا في
+
+324
+00:23:26,230 --> 00:23:31,200
+مرحلة الطبويةالشمس تدخل من خلال ميوكس الشمسيكي
+
+325
+00:23:31,200 --> 00:23:34,880
+اللي كانت مدهشة إلى مستوى ماء أكتر لإيقاف المرحلة
+
+326
+00:23:34,880 --> 00:23:39,200
+الأسهل مرة داخل الشمس الشمسيكية الميوكس الميوكس
+
+327
+00:23:39,200 --> 00:23:44,240
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+328
+00:23:44,240 --> 00:23:44,500
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+329
+00:23:44,500 --> 00:23:44,560
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+330
+00:23:44,560 --> 00:23:44,660
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+331
+00:23:44,660 --> 00:23:56,720
+الميوكس الميوكس الميوكس الميوكس
+
+332
+00:23:56,720 --> 00:23:57,640
+الميوك
+
+333
+00:24:04,790 --> 00:24:08,630
+النظام اللي اخطط السمك لطفولات غريبه تدمر أكتر من
+
+334
+00:24:08,630 --> 00:24:11,810
+الآلاف و أكتر منها تدمر أكتر منها تدمر أكتر منها
+
+335
+00:24:11,810 --> 00:24:16,790
+تدمر أكتر منها تدمر
+
+336
+00:24:16,790 --> 00:24:18,990
+أكتر منها تدمر أكتر منها تدمر أكتر منها تدمر أكتر
+
+337
+00:24:18,990 --> 00:24:19,410
+منها تدمر أكتر منها تدمر أكتر منها تدمر أكتر منها
+
+338
+00:24:19,410 --> 00:24:19,470
+تدمر أكتر منها تدمر أكتر منها تدمر أكتر منها تدمر
+
+339
+00:24:19,470 --> 00:24:26,570
+منها تدمر أكتر منها تدمر أكتر منها تدمر أكتر منها
+
+340
+00:24:26,570 --> 00:24:30,720
+تدمرInside the fallopian tube, tiny cilia push the
+
+341
+00:24:30,720 --> 00:24:34,500
+egg toward the uterusTo continue, the sperm must
+
+342
+00:24:34,500 --> 00:24:37,920
+surge against this motion to reach the eggSome
+
+343
+00:24:37,920 --> 00:24:41,920
+sperm get trapped in the cilia and dieDuring this
+
+344
+00:24:41,920 --> 00:24:44,380
+part of the journey, chemicals in the reproductive
+
+345
+00:24:44,380 --> 00:24:46,820
+tract cause the membranes covering the heads of
+
+346
+00:24:46,820 --> 00:24:50,000
+the sperm to change حتى بيقوللي في بعض الدراسات
+
+347
+00:24:50,000 --> 00:24:52,380
+بيقولك السيلية الموجودة في ال fallopian tube اللي
+
+348
+00:24:52,380 --> 00:24:56,420
+المفروض يتساعد البويضة على النزولقد تقتل الـ Spare
+
+349
+00:24:56,420 --> 00:25:01,840
+من خلال تعثر الـ Spare .. مش الـ Spare بتعمل كشبكة
+
+350
+00:25:01,840 --> 00:25:05,020
+الـ Spare فبتعمل catching الـ Spare فبالتالي بيخفف
+
+351
+00:25:05,020 --> 00:25:08,540
+و بعمل reduction في الـ Spare count أيضا فبالتالي
+
+352
+00:25:08,540 --> 00:25:12,400
+أصبح الفلوبيري تيوب أيضا البعض النظريات لا تعتبر
+
+353
+00:25:12,400 --> 00:25:16,720
+بيها آمنة okay تعتبر بيها آمنة من حيث ال oxidative
+
+354
+00:25:16,720 --> 00:25:21,290
+stress من حيث ال pHمن حيث مافيه end immune system،
+
+355
+00:25:21,290 --> 00:25:24,990
+من حيث مافيه end mucus أوكي مافيش مشكلة بسميها
+
+356
+00:25:24,990 --> 00:25:29,790
+safe environment، ولكن من حيث السيليا، لاتعتبر
+
+357
+00:25:29,790 --> 00:25:34,410
+safe As a result, the sperm become hydroactive,
+
+358
+00:25:34,870 --> 00:25:36,950
+swimming harder and faster toward their
+
+359
+00:25:36,950 --> 00:25:42,050
+destination At long last, the sperm reach the egg
+
+360
+00:25:45,390 --> 00:25:47,410
+فقط عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+361
+00:25:47,410 --> 00:25:49,070
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+362
+00:25:49,070 --> 00:25:50,130
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+363
+00:25:50,130 --> 00:25:53,770
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+364
+00:25:53,770 --> 00:25:53,850
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+365
+00:25:53,850 --> 00:25:54,150
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+366
+00:25:54,150 --> 00:25:55,470
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+367
+00:25:55,470 --> 00:25:59,490
+عشان عشان عشان عشان عشان
+
+368
+00:26:18,170 --> 00:26:20,650
+بالداخل من المنطقة الـ Pelucida يوجد مكان مليء
+
+369
+00:26:20,650 --> 00:26:26,050
+بالطبقات المطلوبة فقط خارج ممكنات الطفولة الأول
+
+370
+00:26:26,050 --> 00:26:31,050
+ممكن أن يتواصل معها سوف تفيرتليفي الطفولة بعد
+
+371
+00:26:31,050 --> 00:26:35,790
+مهارة غير قوية وعن أعظم فرصة واحدة من الطفولة تقع
+
+372
+00:26:35,790 --> 00:26:40,530
+في ممكنات الطفولة خلال عدة دقيقة من الوقت ممكنات
+
+373
+00:26:40,530 --> 00:26:43,310
+الطفولة الخارجية تتجمد وطفولة الطفولة تدخل فيها
+
+374
+00:26:43,310 --> 00:26:48,120
+هذا الحدث يسبب في تغييرات في ممكنات الطفولةthat
+
+375
+00:26:48,120 --> 00:26:52,200
+prevent other sperm from attaching to it تحكيلي
+
+376
+00:26:52,200 --> 00:26:55,740
+بعد اختراق أول sperm للcell membrane الخاصة
+
+377
+00:26:55,740 --> 00:26:59,380
+بالزونابلوسيدا بيتم حجز هذا ال sperm في الداخل
+
+378
+00:26:59,380 --> 00:27:04,120
+وتغيير التركيب الكيميائي الخاص بالزونابلوسيدا لمنع
+
+379
+00:27:04,120 --> 00:27:08,420
+دخول أي sperm آخر عشان كده البويضة لا تلقح إلا ب
+
+380
+00:27:08,420 --> 00:27:11,820
+single sperm اللذي يلقح اللذي يلقح البويضة هو
+
+381
+00:27:11,820 --> 00:27:17,500
+الأسرع والذي يصل بشكل أسرعفبالتالي لا يوجد بويضة
+
+382
+00:27:17,500 --> 00:27:21,360
+تُلقّح بأكثر من الـ sperm لا يوجد بويضة تُلقّح
+
+383
+00:27:21,360 --> 00:27:24,940
+بأكثر من الـ sperm لعدة أسباب هتتكلم عنها أولها
+
+384
+00:27:24,940 --> 00:27:28,520
+تغيير التركيب الكيميائي للـ receptor و خاص بيه على
+
+385
+00:27:28,520 --> 00:27:31,900
+سطح الـ zoonocyte خاص بالـ sperm Next, the egg
+
+386
+00:27:31,900 --> 00:27:34,500
+releases chemicals that push other sperm away from
+
+387
+00:27:34,500 --> 00:27:37,400
+the egg and create an impenetrable fertilization
+
+388
+00:27:37,400 --> 00:27:41,620
+membrane السبب التاني أن البويضة نفسها بعد عملية
+
+389
+00:27:41,620 --> 00:27:44,550
+ال fertilization تبدأ تفرز مواد كيميائيةتعمل
+
+390
+00:27:44,550 --> 00:27:48,430
+elimination أو طرد للـ sperm فتمنعه من عملية الـ
+
+391
+00:27:48,430 --> 00:27:51,390
+penetration as the reaction spreads outward the
+
+392
+00:27:51,390 --> 00:27:54,510
+zona pellucida hardens trapping any sperm unlucky
+
+393
+00:27:54,510 --> 00:27:59,750
+enough to be caught inside outside
+
+394
+00:27:59,750 --> 00:28:02,850
+the egg sperm are no longer able to attach to the
+
+395
+00:28:02,850 --> 00:28:07,610
+zona pellucida ال zona pellucida أيضا أصبحت very
+
+396
+00:28:07,610 --> 00:28:10,790
+hard فبالتالي ال sperm مش هيقدر يخترقها يعني تلت
+
+397
+00:28:10,790 --> 00:28:16,340
+أسباب تمنعتلقيح البوايضة بأكثر من الـ sperm بمجرد
+
+398
+00:28:16,340 --> 00:28:19,720
+دخول one sperm أو first sperm للبوايضة البوايضة
+
+399
+00:28:19,720 --> 00:28:23,660
+بتغير ال receptor الخاصة بـ spermatozoon مولودة
+
+400
+00:28:23,660 --> 00:28:26,920
+على سطحها بتصير الـ zoonablecida أكثر صلابة
+
+401
+00:28:26,920 --> 00:28:29,840
+البوايضة بتفرز بعض المواد الكيميائية اللي بتعمل
+
+402
+00:28:29,840 --> 00:28:35,760
+elimination لل sperm meanwhile inside the egg the
+
+403
+00:28:35,760 --> 00:28:38,560
+tightly packed male genetic material spreads out
+
+404
+00:28:40,790 --> 00:28:44,610
+تنظيم جديد يتطور حول المادة الجنية ويصنع الـ
+
+405
+00:28:44,610 --> 00:28:49,350
+Pronucleus الرجل في الداخل، المادة الجنية تتطور
+
+406
+00:28:49,350 --> 00:28:53,610
+مرة أخرى إلى 23 كرموزومتين المادة الجنية الفتاة
+
+407
+00:28:53,610 --> 00:28:56,710
+تتطور بمعالجة التعزيز من الزبدة مع الزبدة التي
+
+408
+00:28:56,710 --> 00:28:57,570
+تنتهي في المزيد من المزيد من المزيد من المزيد من
+
+409
+00:28:57,570 --> 00:29:00,130
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+410
+00:29:00,130 --> 00:29:01,570
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+411
+00:29:01,570 --> 00:29:01,950
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+412
+00:29:01,950 --> 00:29:03,130
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+413
+00:29:03,130 --> 00:29:04,490
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+414
+00:29:04,490 --> 00:29:05,650
+المزيد
+
+415
+00:29:09,770 --> 00:29:14,250
+واتجههم إلى بعضهم البعض الانتجارات الانتجارات
+
+416
+00:29:14,250 --> 00:29:17,710
+الانتجارات تتجمع مع بعضها البعض تكمل عملية التنمية
+
+417
+00:29:17,710 --> 00:29:22,370
+في هذه اللحظة تتجه موضوع كودة جينيكي مميز للجنس
+
+418
+00:29:22,370 --> 00:29:25,910
+بسرعة تقوم بتحديد جمهورية، ورقم العيون، ورقم
+
+419
+00:29:25,910 --> 00:29:29,910
+العيون، ومئات أخرى شخصية مختلفة. هذا الجلد
+
+420
+00:29:29,910 --> 00:29:32,730
+الانتجاري الانتجاري الانتجاري الانتجاري الانتجاري
+
+421
+00:29:32,730 --> 00:29:33,210
+الانتجاري الانتجاري الانتجاري الانتجاري الانتجاري
+
+422
+00:29:33,210 --> 00:29:36,840
+الانتجاري الانتجاريAnd now the cilia in the
+
+423
+00:29:36,840 --> 00:29:39,900
+fallopian tube gently sweep the zygote toward the
+
+424
+00:29:39,900 --> 00:29:42,720
+uterus, where he or she will implant in the rich
+
+425
+00:29:42,720 --> 00:29:45,840
+uterine lining, growing and maturing for the next
+
+426
+00:29:45,840 --> 00:29:51,000
+nine months until ready for birth هذه
+
+427
+00:29:51,000 --> 00:29:54,680
+عبارة عن رحلة تدخل ال sperm خلال ال female
+
+428
+00:29:54,680 --> 00:29:58,440
+reproductive tract وصولا إلى القنوات التي لها
+
+429
+00:29:58,440 --> 00:30:03,730
+علاقة بالميبياأو القنوات fallopian tube التي لها
+
+430
+00:30:03,730 --> 00:30:09,170
+علاقة بعملية التوقيح حيث تحدث في الثلث الأعلى من
+
+431
+00:30:09,170 --> 00:30:13,770
+fallopian tube أعرفنا كيف بتم عملية نقل ال sperm
+
+432
+00:30:13,770 --> 00:30:18,930
+إيش أهم ال action اللي بتصير على ال sperm مجرد
+
+433
+00:30:18,930 --> 00:30:23,210
+وصوله لل fallopian tube تحت مصطلح capacitation و
+
+434
+00:30:23,210 --> 00:30:27,450
+hyperactivation تحت مصطلح capacitation و
+
+435
+00:30:27,450 --> 00:30:34,480
+hyperactivationهنتقف عن هذا الحد في محاضرة اليوم،
+
+436
+00:30:34,480 --> 00:30:38,320
+على أمل أن نلتقي في محاضرة قادمة ان شاء الله،
+
+437
+00:30:38,320 --> 00:30:40,780
+دومتم بخير وفي حفظ الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/04ZuGxhhn40_raw.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/04ZuGxhhn40_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..1fdd0ce726720d087c012cccd20094f2c63ae540
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/04ZuGxhhn40_raw.srt
@@ -0,0 +1,1752 @@
+1
+00:00:01,920 --> 00:00:05,800
+باسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,800 --> 00:00:11,640
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين أرجو من
+
+3
+00:00:11,640 --> 00:00:16,060
+الله الكريم أن تكونوا بخير جميعا استكمالا لما
+
+4
+00:00:16,060 --> 00:00:20,960
+تحدثنا فيه في المحاضرة السابقة حول عملية انتقال
+
+5
+00:00:20,960 --> 00:00:25,060
+النطف الذكيرية في الـ reproductive track الخاصة
+
+6
+00:00:25,060 --> 00:00:28,080
+بالمال والنطف الأنثوية في ال female reproductive
+
+7
+00:00:28,080 --> 00:00:34,240
+trackوقفنا في المحاضرة السابقة عند كلمة مهمة جدا
+
+8
+00:00:34,240 --> 00:00:38,520
+وهي عبارة عن Coagulum حكينا أن الـ Coagulum هي
+
+9
+00:00:38,520 --> 00:00:43,280
+عبارة عن تجلّقات بسيطة بفعل بروتينات موجودة في الـ
+
+10
+00:00:43,280 --> 00:00:47,780
+seminal fluid تعمل معامل ال network الشبكة التي
+
+11
+00:00:47,780 --> 00:00:52,580
+تحمل sperm بالداخل منالـ environment الخشنة أو
+
+12
+00:00:52,580 --> 00:00:55,700
+الغريبة أو الضارة الموجودة في ال reproductive
+
+13
+00:00:55,700 --> 00:01:00,020
+tract الخاصة بالفيميل وخاصة منطقة الفيجاينة بإضافة
+
+14
+00:01:00,020 --> 00:01:05,060
+إلى اختلاف الـ pH هذه الـ coagulant لازم يصير فيها
+
+15
+00:01:05,060 --> 00:01:11,400
+عملية dissolving أو losing عشان تتيح الفرصة لهذا
+
+16
+00:01:11,400 --> 00:01:16,700
+ال sperm ان يتحرك وصولا إلى منطقة ال cervicalبعد
+
+17
+00:01:16,700 --> 00:01:22,040
+حوالي 30 إلى 60 دقيقة من عملية خسارة الكواكولا
+
+18
+00:01:22,040 --> 00:01:27,360
+لبروستاتا لبروستاتا مخصصة انتجين وإنزايم بروتاليتك
+
+19
+00:01:27,360 --> 00:01:33,520
+سيكون مفرد ويخسر السمن الكواكولاتي في السمن
+
+20
+00:01:33,520 --> 00:01:37,740
+والتراث الفيجينالي الفلويد الاسبامي يبدأ بالمشاركة
+
+21
+00:01:37,740 --> 00:01:45,750
+بمجرد عملية .. بمجرد عمليةتحلل الكواجولام المحيط
+
+22
+00:01:45,750 --> 00:01:49,330
+بالـ sperm بتاع بعض الإنزيمات التي تكون موجودة في
+
+23
+00:01:49,330 --> 00:01:52,930
+الـ seminal fluid وأشهر بروستاتيك specific antigen
+
+24
+00:01:52,930 --> 00:01:55,330
+أو البروستاتيك specific antigen بالإضافة إلى الـ
+
+25
+00:01:55,330 --> 00:01:59,530
+proteolytic enzyme هذا يؤدي إلى تحلل الكواجولام،
+
+26
+00:01:59,530 --> 00:02:02,410
+تكسر البروتينات التي تعمل الـ coagulation حول الـ
+
+27
+00:02:02,410 --> 00:02:06,320
+spermفبالتالي الـ sperm بيكون حُب و بيبدأ يستطيع
+
+28
+00:02:06,320 --> 00:02:11,720
+الحركة والسباحة في اتجاه الفلوبيانيتيوب a critical
+
+29
+00:02:11,720 --> 00:02:15,380
+element in the sperm motility is the atayability
+
+30
+00:02:15,380 --> 00:02:19,580
+of fructose أهم شغل في ال sperm motility توفر كمية
+
+31
+00:02:19,580 --> 00:02:24,260
+كافية من الفرقتوز because of their leak of
+
+32
+00:02:24,260 --> 00:02:27,360
+cytoplasmic spermatozoa required an external
+
+33
+00:02:27,360 --> 00:02:32,680
+energy source بدون الفرقتوزما في قدرة على الحركة
+
+34
+00:02:32,680 --> 00:02:36,420
+علشان كده ممكن بعض الذكور يكون عنده الكون طبيعي
+
+35
+00:02:36,420 --> 00:02:41,420
+الحركة غير طبيعية بفعل شيء واحد وهو كمية ال
+
+36
+00:02:41,420 --> 00:02:44,440
+fractose الموجودة في السيمن والتي تستخدم كمصدر
+
+37
+00:02:44,440 --> 00:02:49,600
+أساسي للطاقة الخاصة بال sperm غير موجودة فلو تم
+
+38
+00:02:49,600 --> 00:02:55,280
+عمل فحص لل fractose test الذي يهمل بفعل بعضالمراكز
+
+39
+00:02:55,280 --> 00:03:00,340
+أو بعض المختبرات هيمكن تشخص الحالة المرضية يكون
+
+40
+00:03:00,340 --> 00:03:03,680
+علاجها بسيط جدا هي تناول فواكه تحتوى على الفركتوز
+
+41
+00:03:03,680 --> 00:03:06,880
+أو أخذ بعض المكملات الغذائية التي تحتوى على
+
+42
+00:03:06,880 --> 00:03:11,020
+الفركتوز usually for most cells spermatozoa have a
+
+43
+00:03:11,020 --> 00:03:13,560
+specific requirement for fructose rather than
+
+44
+00:03:13,560 --> 00:03:17,300
+glycose the more commonly utilized carbohydrate
+
+45
+00:03:17,300 --> 00:03:21,100
+energy source بيحكيلي أن ال spermatozoa أو ال
+
+46
+00:03:21,100 --> 00:03:25,690
+sperm كنطفة أو كخليةتختلف عن الخلايا الأخرى في
+
+47
+00:03:25,690 --> 00:03:29,910
+مصدرها للطاقة فمعظم الخلايا تستخدم الجليكوز كمصدر
+
+48
+00:03:29,910 --> 00:03:34,770
+للطاقة باستثناء الـ spermatozoa تستخدم الفراكتوز
+
+49
+00:03:34,770 --> 00:03:39,050
+وذلك لسببين حركتها السريعة جدا و التي تحتاج إلى
+
+50
+00:03:39,050 --> 00:03:43,330
+كمية هائلة من الطاقة بشكل مستمر فبالتالي احتراق
+
+51
+00:03:43,330 --> 00:03:48,000
+الفراكتوز لإنتاج الطاقة أسرع من احتراق الجليكوزإلى
+
+52
+00:03:48,000 --> 00:03:51,180
+بعض الإنزيمات المسؤولة عن احتراق الجليكوز زي
+
+53
+00:03:51,180 --> 00:03:54,240
+الـNexokinase وبالتالي اللي يمكن استخدامه بالطريقة
+
+54
+00:03:54,240 --> 00:03:59,400
+التي تستخدم فيها الفركتورز الـnexpires أو تاني
+
+55
+00:03:59,400 --> 00:04:05,080
+حاجز أو تاني خطر بجابل الـSperm إعبار عن منطقة
+
+56
+00:04:05,080 --> 00:04:07,700
+الـcervix الـcervical entrance
+
+57
+00:04:11,120 --> 00:04:14,980
+it is not only very small but it is blocked by
+
+58
+00:04:14,980 --> 00:04:19,260
+cervical mucus اتخلص ال sperm من ال pH الخاص
+
+59
+00:04:19,260 --> 00:04:24,400
+بالفاجينه وصل لأعتاب ال cervic يصطدم بخطر تاني وهو
+
+60
+00:04:24,400 --> 00:04:27,980
+عبارة عن مدخل ال cervic مدخل ال cervic فيه مشكلتين
+
+61
+00:04:27,980 --> 00:04:32,060
+المشكلة الأولى انه very close او very inner very
+
+62
+00:04:32,060 --> 00:04:36,840
+smallالشغل التاني انه مغلق بكمية كبيرة جدا من ال
+
+63
+00:04:36,840 --> 00:04:41,860
+ميوكاس تسمى cervical mucus طبعا during the most
+
+64
+00:04:41,860 --> 00:04:44,640
+time of menstrual cycle ال cervical mucus is very
+
+65
+00:04:44,640 --> 00:04:50,600
+high stick and very difficult to penetrate خلال
+
+66
+00:04:50,600 --> 00:04:54,160
+عملية menstrual cycle بنلاقي ال cervical مغلق
+
+67
+00:04:54,160 --> 00:04:57,960
+بكمية كبيرة جدا من الميوكاس الغليظة التي يصعب
+
+68
+00:04:57,960 --> 00:05:01,910
+اختراقهاوهذا نوع من أنواع الحماية، وهذا نوع من
+
+69
+00:05:01,910 --> 00:05:07,510
+أنواع الحماية حتى لو الـ Sperm صار Intercourses في
+
+70
+00:05:07,510 --> 00:05:11,730
+غير موضع الأبويد يعني القريب من ال menstrual cycle
+
+71
+00:05:11,730 --> 00:05:15,130
+أو ال period بتاعة ال menstrual cycle يصعب على ال
+
+72
+00:05:15,130 --> 00:05:20,670
+sperm اختراق هذه الكمية العقلة من ال mucusطب شو
+
+73
+00:05:20,670 --> 00:05:23,970
+اللي بيخلّي الميوكاس very stick أو very thick؟ هي
+
+74
+00:05:23,970 --> 00:05:27,290
+حاجة بتسميها cervical myosin هي نوع من أنواع
+
+75
+00:05:27,290 --> 00:05:30,550
+الجليكوبروتين وهو عبارة with high carbohydrate
+
+76
+00:05:30,550 --> 00:05:33,770
+composition الجليكوبروتين هو عبارة عن كمية كبيرة
+
+77
+00:05:33,770 --> 00:05:37,310
+جدا من الكربوهيدرات متصلة مع البروتين and soluble
+
+78
+00:05:37,310 --> 00:05:40,330
+compound cervical mucus is not ready penetration
+
+79
+00:05:40,330 --> 00:05:46,340
+يعني هذه ال cervical myosinتجعل الميوكاس الموجود
+
+80
+00:05:46,340 --> 00:05:49,860
+على مقدمة الـ cervic أو مدخل الـ cervical صاحب
+
+81
+00:05:49,860 --> 00:05:53,640
+اختراقه طب إيه اللي بيخلي الـ sperm قادر على
+
+82
+00:05:53,640 --> 00:05:56,820
+اختراقه؟ بيقول لك في أيام الطبوية اليوم 13 و اليوم
+
+83
+00:05:56,820 --> 00:06:01,800
+14 الهرمونات التي تفرز بفعل الـ ovary زي الـ
+
+84
+00:06:01,800 --> 00:06:05,300
+estrogenic hormone بعمل على تكوين الـ estrogenic
+
+85
+00:06:05,300 --> 00:06:10,140
+environment هذا اللي بتخلي الـ mucus very loose
+
+86
+00:06:10,140 --> 00:06:14,350
+بتعمل change في ال formationوفي الـ composition
+
+87
+00:06:14,350 --> 00:06:19,630
+وفي قوام ال cervical mucus فبصير بعد ما كان very
+
+88
+00:06:19,630 --> 00:06:24,170
+thick, very sticky, very thickness بصير watery سهل
+
+89
+00:06:24,170 --> 00:06:29,010
+ال penetration بفعل اسباب تصور متى؟ في لحظة أو
+
+90
+00:06:29,010 --> 00:06:32,270
+أيام الطبويل بصير إفراز كمية كبيرة جدا من
+
+91
+00:06:32,270 --> 00:06:36,370
+الاستروجين بيكون استروجينك environment بيغير طبيعة
+
+92
+00:06:36,370 --> 00:06:42,330
+ال cervical mucus بيخليه من stickyإلى واتري سهل ال
+
+93
+00:06:42,330 --> 00:06:47,830
+penetration بفعل ال sperm ال wire رقم تلاتة اللي
+
+94
+00:06:47,830 --> 00:06:51,710
+بيواجه ال sperm هو خلال عملية الانتقال بعد دخوله
+
+95
+00:06:51,710 --> 00:06:55,150
+ال cervic هي ال immunological شو يعني
+
+96
+00:06:55,150 --> 00:06:58,730
+immunological؟ يعني جهاز المناعة جهاز المناعة
+
+97
+00:06:58,730 --> 00:07:02,650
+بتعامل مع ال sperm كأنه foreign substance و طالما
+
+98
+00:07:02,650 --> 00:07:06,230
+هو foreign substance إذا بيحفظ جهاز المناعة فبيبدأ
+
+99
+00:07:06,230 --> 00:07:12,230
+جهاز المناعة يقتلالـ sperm بفعل الخلايا البلعمية
+
+100
+00:07:12,230 --> 00:07:17,690
+زي النيتروفيل و الـ Vagocyte الفاجينة و أيضًا الـ
+
+101
+00:07:17,690 --> 00:07:22,550
+cervic استخدمت استراتيجية إميونولوجية لإنقاذ الـ
+
+102
+00:07:22,550 --> 00:07:26,750
+pathogen من الانتقال و الانتقال إلى الـ cervical
+
+103
+00:07:26,750 --> 00:07:30,510
+للوصول إلى الجزء الأعلى من الـ female reproductive
+
+104
+00:07:30,510 --> 00:07:34,710
+tract و المقصود فيها الرحم و الـ fallopian tube
+
+105
+00:07:34,710 --> 00:07:37,490
+لأن لو ال pathogen وصل للرحم و الـ fallopian tube
+
+106
+00:07:37,680 --> 00:07:42,340
+يعني صار فيه إلتهاب، إلتهاب يعني ممكن يصير تقرحات،
+
+107
+00:07:42,340 --> 00:07:45,860
+تقرحات يعني ممكن يصير عندي adhesion، ligament
+
+108
+00:07:45,860 --> 00:07:49,240
+adhesion، endometriosis، يعني في الغالب
+
+109
+00:07:49,240 --> 00:07:54,640
+infertility طبعا من أشهر الخلايا التي تساهم في هذه
+
+110
+00:07:54,640 --> 00:07:57,580
+الحماية هي عبارة عن الـ Neutrophil و ال macro و ال
+
+111
+00:07:57,580 --> 00:08:01,000
+macrophage بالإضافة إلى بعض الـ monoglobulin like
+
+112
+00:08:01,000 --> 00:08:06,080
+IgAand IGG وال IGG بالذات لإنه very small في ال
+
+113
+00:08:06,080 --> 00:08:10,920
+size وال IGA لإنه ممكن يتواجد في ال secretion
+
+114
+00:08:10,920 --> 00:08:16,120
+فبالتالي لم يتم اختيار ال IGA وال IGG عبثا ولكن ال
+
+115
+00:08:16,120 --> 00:08:19,340
+IGG بسبب صغر حجمه فبالتالي ممكن يعمل filtration
+
+116
+00:08:19,340 --> 00:08:23,500
+لأى مكان وال IGA لإنه سهل تواجده في ال secretion
+
+117
+00:08:23,500 --> 00:08:28,080
+فهيكلامه بيشتغل ضد أي foreign substance بيمنعه من
+
+118
+00:08:28,080 --> 00:08:34,520
+ال invasionالسيرماتوزوه أيضًا تحفز بعض هذه
+
+119
+00:08:34,520 --> 00:08:40,200
+الدفاعات لإيقاف أكتر منها في ترانزيانها إلى داخل
+
+120
+00:08:40,200 --> 00:08:45,060
+السيرفيكال رغم أن السيرماتوزوه تستطيع أن تحفز أحد
+
+121
+00:08:45,060 --> 00:08:49,260
+هذه الـ buyers الخاصة بالإيميونولوجيكال إلى أنها
+
+122
+00:08:49,260 --> 00:08:52,600
+تستطيع أن تتغلب عليهم وإلا كيف تصير عملية ال
+
+123
+00:08:52,600 --> 00:08:57,460
+fertilization بعد 24 ساعة من بقاء السيرم في منطقة
+
+124
+00:08:57,460 --> 00:09:01,290
+السيرفيكالبتبدأ ال Vagocyte تشتغل المتمثلة في الـ
+
+125
+00:09:01,290 --> 00:09:06,810
+Neutrophil و Macrophage بتعمل Vagocytosis و
+
+126
+00:09:06,810 --> 00:09:12,050
+Engulfing للـ spermatozoa فبتعمل reduction في عدد
+
+127
+00:09:12,050 --> 00:09:16,030
+ال spermatozoa التي قد تصل إلى ال Oocyte فبدل ما
+
+128
+00:09:16,030 --> 00:09:20,570
+يصل مليون بيصل 200 ألف، 300 ألف، 400 ألف، 900 ألف
+
+129
+00:09:20,570 --> 00:09:23,970
+يعني بصلا يطلع عندي 50 مليون، 20 مليون، 30 مليون،
+
+130
+00:09:23,970 --> 00:09:28,140
+300 مليونبصل لكمية بالألاف فقط لغير واحد منهم
+
+131
+00:09:28,140 --> 00:09:32,620
+يستطيع تلقيه القوائد الـ swimming speed of the
+
+132
+00:09:32,620 --> 00:09:36,800
+human sperm in the fluid is approximately five
+
+133
+00:09:36,800 --> 00:09:41,220
+millimeters per minute لو أنا قرنت حركة ال sperm
+
+134
+00:09:41,220 --> 00:09:45,180
+في الوضع الطبيعي بناجي سرعة ال sperm تصل خمسة ملي
+
+135
+00:09:45,180 --> 00:09:48,800
+متر في الدقيقة يعني بالوضع النظري المعقول و
+
+136
+00:09:48,800 --> 00:09:52,540
+الحسابات المعقولة عشان يصل للمنطقة المطلوبة منه
+
+137
+00:09:52,540 --> 00:09:57,540
+بحتاج إلى minuteأو hours، ولكن بعض الدراسات وجدت
+
+138
+00:09:57,540 --> 00:10:03,500
+أن فيه الـSperm وصل للأعلى جزء من الفلوبيا نتيوب
+
+139
+00:10:03,500 --> 00:10:07,860
+خلال دقائق بعد عملية الـintercourses فهذه نظرياً
+
+140
+00:10:07,860 --> 00:10:11,240
+okay، ولكن عملياً شيء آخر خلّيني أشوف كيف ال
+
+141
+00:10:11,240 --> 00:10:16,200
+vagocytosis بتشتغل على الـSperm خلال بقاءه في
+
+142
+00:10:16,200 --> 00:10:21,160
+منطقة الـcervical بعد 24 ساعة، إن لم يتخطى هذا
+
+143
+00:10:21,160 --> 00:10:29,230
+الحاجزنشوف إيش بيصير في هذه العملية الـ
+
+144
+00:10:29,230 --> 00:10:32,270
+sperm are foreign to a woman's body and are
+
+145
+00:10:32,270 --> 00:10:38,870
+treated as unwanted invaders her
+
+146
+00:10:38,870 --> 00:10:44,190
+immune system is triggered to kill them once they
+
+147
+00:10:44,190 --> 00:10:48,050
+enter the cervix they are in a labyrinth of dead
+
+148
+00:10:48,050 --> 00:10:51,510
+ends perfect
+
+149
+00:10:51,510 --> 00:10:52,450
+for an ambush
+
+150
+00:10:56,050 --> 00:11:02,650
+هذا البروسايت الورقاء
+
+151
+00:11:02,650 --> 00:11:09,850
+يهاجمون الحرارة من جميع الاتجاهات
+
+152
+00:11:09,850 --> 00:11:21,290
+عندما
+
+153
+00:11:21,290 --> 00:11:26,000
+يصل أي ناجين للأمان من حفرة فولوبياof the original
+
+154
+00:11:26,000 --> 00:11:34,640
+250 million that could be as few as 20 left يعني
+
+155
+00:11:34,640 --> 00:11:38,860
+بيحكي ليه أن أول منطقة تعتبر أمنة لل sperm هي
+
+156
+00:11:38,860 --> 00:11:42,360
+الferopian tube بعد ما يقطع ال sperm كل هذه
+
+157
+00:11:42,360 --> 00:11:47,840
+العوائق و المخاطر تقريبا بيصل 200 sperm 300 sperm
+
+158
+00:11:47,840 --> 00:11:52,180
+ممكن يصل 10 و ممكن يصل 20 و ممكن يصل 50 هذا يعتمد
+
+159
+00:11:52,180 --> 00:11:57,670
+جديش PNDSperm في عملية ال ejaculation فبالتالي كل
+
+160
+00:11:57,670 --> 00:12:01,370
+مراحل التي يمر بها ال sperm مرورا من الفيجاينة
+
+161
+00:12:01,370 --> 00:12:05,630
+مدخل ال cervical ال cervical هذه مراحل خطرة أول
+
+162
+00:12:05,630 --> 00:12:09,530
+مرحلة تعتبر آمنة لل sperm هي ال fallopian tube
+
+163
+00:12:09,530 --> 00:12:16,690
+fallopian tube صورة بتوضح الكلام اللي احنا حكيناه
+
+164
+00:12:16,690 --> 00:12:21,150
+تلاحظ في عندي مطيقة طبعا في عندي هنا واحد اتنين
+
+165
+00:12:21,150 --> 00:12:25,280
+تلاتة اربع خمسة ستة مناطقوتحت كل منطقة فيها عدد ال
+
+166
+00:12:25,280 --> 00:12:28,860
+sperm اللي بيكون فيها فبالتالي أول منطقة sperm
+
+167
+00:12:28,860 --> 00:12:32,600
+dump aside in the upper في جنة يعني المنطقة اللي
+
+168
+00:12:32,600 --> 00:12:36,080
+بيصير فيها عملية ال ejaculation بيكون فيها كل عدد
+
+169
+00:12:36,080 --> 00:12:39,640
+ال sperm قد يصل إلى عشرة والسبعة يعني بالملايين،
+
+170
+00:12:39,640 --> 00:12:44,000
+عشرة مليون، اشرين مليون، تلاتين مليون يعتمد جداش
+
+171
+00:12:44,000 --> 00:12:50,700
+في عنده عينة المال يليها مباشرة ال cervic يدخل من
+
+172
+00:12:50,700 --> 00:12:55,390
+خلال ال cervicبسل في المرحلة ال base through
+
+173
+00:12:55,390 --> 00:13:01,730
+cervical ال fast slow phase مليون تقريبا base
+
+174
+00:13:01,730 --> 00:13:07,590
+passage through المدخل الخاص بالرحم يوترست بسل
+
+175
+00:13:07,590 --> 00:13:11,890
+عندي كمان عشرة أوس خمسة يعني بالعشر تلاف عشرين ألف
+
+176
+00:13:11,890 --> 00:13:17,850
+تلاتين ألف مدخل القنابيب الخاصة بالفلو بين الطيوب
+
+177
+00:13:17,850 --> 00:13:22,250
+بسل عشرة أوس أربعةالمرحلة التالتة هي عبارة عن
+
+178
+00:13:22,250 --> 00:13:26,050
+السباحة وصولا إلى منطقة الفنوبيا التيوبة التي يحدث
+
+179
+00:13:26,050 --> 00:13:29,550
+فيها التبويض التي يحدث فيها التبويض تسمى ال
+
+180
+00:13:29,550 --> 00:13:32,890
+fertilization بصل .. بعدين بصل لمنطقة ال
+
+181
+00:13:32,890 --> 00:13:37,450
+fertilization بيكون مية إلى ألف يعني فقط البصل
+
+182
+00:13:37,450 --> 00:13:40,750
+للمنطقة اللي بيصير عندها ال fertilization تقريبا
+
+183
+00:13:40,750 --> 00:13:45,590
+يا إما بالمئات يا إما بالألف لا تتجاوز الألف شوف
+
+184
+00:13:45,590 --> 00:13:48,490
+كيف بيصير عندي reduction في ال count من عشر أقل
+
+185
+00:13:48,490 --> 00:13:53,770
+سبعةالعشرة أُس ثلاثة من عشرة أُس سبعة إلى عشرة أُس
+
+186
+00:13:53,770 --> 00:13:58,270
+ثلاثة يعني من عشرة مليون وخمسين مليون وسبعين مليون
+
+187
+00:13:58,270 --> 00:14:04,930
+إلى ألف فقط ده بيعمل طبعا there are two type of
+
+188
+00:14:04,930 --> 00:14:08,670
+sperm transportation through the cervix الطريقة
+
+189
+00:14:08,670 --> 00:14:12,750
+الأولى هي ال fast أو ال first خلينا نسميها تتميز
+
+190
+00:14:12,750 --> 00:14:16,870
+هنا initial rapidly transport يعني عبارة عن عملية
+
+191
+00:14:16,870 --> 00:14:22,510
+نقلبطيئة سريعة جدا انه يشهر Rapidly Transport by
+
+192
+00:14:22,510 --> 00:14:26,510
+which some spermatozoa can arrive to the uterine
+
+193
+00:14:26,510 --> 00:14:30,330
+tube within five to ten minutes of ejaculation هذا
+
+194
+00:14:30,330 --> 00:14:34,690
+الطريقة السريعة اللي من خلالها يستطيع ال sperm أن
+
+195
+00:14:34,690 --> 00:14:40,370
+يصل إلى القنوات الإباضة أو القنوات الفلو أو
+
+196
+00:14:40,370 --> 00:14:44,430
+القنوات المبيض خلال خمسة إلى عشرين دقيقة
+
+197
+00:14:47,050 --> 00:14:50,570
+أما النوع التاني من الحركة .. الحركة اللي بنسميها
+
+198
+00:14:50,570 --> 00:14:55,210
+slow phase of sperm transport وهذه طبعا بيصير فيها
+
+199
+00:14:55,210 --> 00:15:00,230
+swimming للـ sperm through the cervical mucus معدل
+
+200
+00:15:00,230 --> 00:15:05,870
+انتقاله 2 إلى 3 ملي متر في الساعة their storage on
+
+201
+00:15:05,870 --> 00:15:09,370
+the cervical and their final passage through the
+
+202
+00:15:09,370 --> 00:15:15,450
+cervical canal as much as 2 to 4 days laterمين
+
+203
+00:15:15,450 --> 00:15:18,710
+بيهمني الأولى ولا التانية؟ كلاهم يدعم بعضهم الآخر،
+
+204
+00:15:18,710 --> 00:15:22,430
+ماقدر أصل للتانية إذا أنا مابدأتش بالأولى، لأن
+
+205
+00:15:22,430 --> 00:15:25,890
+الأولى هي اللي هتخلي الـSperm يقطع الـcervical
+
+206
+00:15:25,890 --> 00:15:29,290
+ويقطع الـcervical canal يقطع الـcervical ويقطع
+
+207
+00:15:29,290 --> 00:15:34,530
+الـcervical canal once inside the fallopian tube
+
+208
+00:15:34,530 --> 00:15:38,230
+الـspermatozoa influences isocretion of the tube
+
+209
+00:15:38,230 --> 00:15:41,930
+to undergo the capacitation reactionمجرد ما يصل
+
+210
+00:15:41,930 --> 00:15:45,650
+الـ sperm للـ fallopian tube بدا الـ sperm يتأثر
+
+211
+00:15:45,650 --> 00:15:49,130
+ببعض الإفرازات اللي بتفرزها الـ fallopian tube أو
+
+212
+00:15:49,130 --> 00:15:54,290
+الـ tubular بشكل عام هذه الـ tube بتفرز مواد بتخلي
+
+213
+00:15:54,290 --> 00:15:58,730
+ال sperm أكثر قدرة على التلقيح there are two
+
+214
+00:15:58,730 --> 00:16:02,750
+critical events that occur during this period إيش
+
+215
+00:16:02,750 --> 00:16:06,110
+بيصير خلال وجوده في الـ fallopian tube؟ شغل تاني
+
+216
+00:16:06,110 --> 00:16:11,620
+الشغل التاني الأولى تسمى capacitationوخلال عملية
+
+217
+00:16:11,620 --> 00:16:15,760
+الcapacitation بيصير في عندي اكتساب ال sperm
+
+218
+00:16:15,760 --> 00:16:20,620
+لمقدرة عالية انه يخص بالبوابة من خلال أول حاجة
+
+219
+00:16:20,620 --> 00:16:23,980
+first phase of capacitation is remove the
+
+220
+00:16:23,980 --> 00:16:27,220
+cholesterol from the surface of sperm عشان يصير
+
+221
+00:16:27,220 --> 00:16:29,900
+capacitation لازم ال sperm يمر بمرحلة تانية
+
+222
+00:16:29,900 --> 00:16:33,700
+المرحلة الأولى ازالت ما يُعرف اسم ال cholesterol
+
+223
+00:16:33,700 --> 00:16:37,400
+droplets الموجودة في منطقة الhead فبيخلي ال sperm
+
+224
+00:16:37,400 --> 00:16:41,140
+أخفالكليسترول الـ droplets مهم جدًا في حماية الـ
+
+225
+00:16:41,140 --> 00:16:47,580
+head للـ sperm الكليسترول تم تطبيقه على الـ sperm
+
+226
+00:16:47,580 --> 00:16:51,480
+head لتمنع الـ premature capacitation إذا أضفت
+
+227
+00:16:51,480 --> 00:16:54,580
+الكليسترول الـ droplets حماية الـ sperm وبتمنع
+
+228
+00:16:54,580 --> 00:16:57,900
+الcapacitation في غير وجهها تحت مسمى premature
+
+229
+00:16:57,900 --> 00:17:02,260
+capacitation should be prevented the next step of
+
+230
+00:17:02,260 --> 00:17:05,160
+capacitation المرحلة التانية من الcapacitation
+
+231
+00:17:05,490 --> 00:17:08,690
+Remove of many of glycoprotein that were
+
+232
+00:17:08,690 --> 00:17:11,170
+hypothesized on the sperm head within the
+
+233
+00:17:11,170 --> 00:17:14,450
+epidermis. After their removal, the spermatozoa is
+
+234
+00:17:14,450 --> 00:17:18,490
+now a chemical core fertilized egg فالكبستيشن
+
+235
+00:17:18,490 --> 00:17:22,290
+بيصير عندي شغل تاني الشغل الأولى كلسترول الدروبلتز
+
+236
+00:17:22,290 --> 00:17:26,930
+الموجودة في ال head يتم التخلص منها الشغل التانى
+
+237
+00:17:26,930 --> 00:17:31,170
+بيصير في عندي removing لكمية من ال glycoprotein
+
+238
+00:17:31,170 --> 00:17:34,840
+الموجودة في ال sperm of headالشغلتين هدولة بيصير
+
+239
+00:17:34,840 --> 00:17:38,520
+الـ sperm قادر على تخصيب المواد الـ second
+
+240
+00:17:38,520 --> 00:17:41,500
+phenomena occur while the sperm are attached to
+
+241
+00:17:41,500 --> 00:17:46,240
+the distal tubule و lining that is hyperactivated،
+
+242
+00:17:46,240 --> 00:17:50,820
+hyperactivation قُلت إن خلال الفلوبيا التيوب بتأثر
+
+243
+00:17:50,820 --> 00:17:54,660
+ال sperm بالsecretion اللي بتفرزف فبيصير فيه حدثين
+
+244
+00:17:54,660 --> 00:17:58,680
+الحدث الأول سميته capacitation و بيصير فيه two
+
+245
+00:17:58,680 --> 00:18:02,610
+phases و الحدث التاني بيسميه hyperactivationبرجع
+
+246
+00:18:02,610 --> 00:18:05,910
+بقول الcapacitation بيصير عندي two phase أو two
+
+247
+00:18:05,910 --> 00:18:08,810
+stage ال stage الأولى التخلص من ال cholesterol
+
+248
+00:18:08,810 --> 00:18:12,050
+droplets اللي موجودة في ال head فبالتالي بيصير أخف
+
+249
+00:18:12,050 --> 00:18:15,490
+ال phase التاني بتخلص من بعض ال glycoprotein
+
+250
+00:18:15,490 --> 00:18:20,710
+فبيصير كده قادر يتحرك بصورة أسرع و قادر على
+
+251
+00:18:20,710 --> 00:18:23,370
+التخصيب الحدث التاني اللي بيصير في فعل ال
+
+252
+00:18:23,370 --> 00:18:27,170
+secretion هي ال hyper activation يعني زيادة حركته
+
+253
+00:18:27,170 --> 00:18:32,360
+زيادة قدرته على الاختراق ال hyper activationهي
+
+254
+00:18:32,360 --> 00:18:37,580
+عبارة عن عملية يُقصد بها زيادة قدرة الـ sperm على
+
+255
+00:18:37,580 --> 00:18:43,420
+السباحة والحركة بيصير كأنه بالظبط زي شنيور إيه
+
+256
+00:18:43,420 --> 00:18:47,160
+المقصود بالشنيور؟ هو عبارة عن الملف أو المجدح اللي
+
+257
+00:18:47,160 --> 00:18:52,880
+بيعمل عملية اختراق للحاقة أو لأي شيء صلي فبصير
+
+258
+00:18:52,880 --> 00:18:55,820
+عندي .. هنشوفها كمان شوية في الفيديو كيف بيصير
+
+259
+00:18:55,820 --> 00:19:00,910
+hyper activation لل spermويصيب الـ sperm قادر إنه
+
+260
+00:19:00,910 --> 00:19:05,330
+يخترق بالضبط زي البرريمة اللي بتعمل على الحفر في
+
+261
+00:19:05,330 --> 00:19:10,490
+الصخر من أجل الحصول والوصول إلى البترول بالضبط and
+
+262
+00:19:10,490 --> 00:19:14,090
+allow the sperm to break free from their binding
+
+263
+00:19:14,090 --> 00:19:16,930
+with the tubule epithelium cell هذا المقصود
+
+264
+00:19:16,930 --> 00:19:20,690
+بالhyperactivity طبعا الhyperactivity assists the
+
+265
+00:19:20,690 --> 00:19:24,530
+sperm to penetration isthmus mucosa and
+
+266
+00:19:24,530 --> 00:19:29,110
+coronaradiataو الـ Zoona Plucida التي تجمع الـ OVA
+
+267
+00:19:29,110 --> 00:19:32,770
+الهيبر اكتيفيشن ليس بصير عبسا، لأ، بتساعد الـ
+
+268
+00:19:32,770 --> 00:19:35,670
+Desperme أن يخلق الـ Multilayer المحيط بالـ OVA
+
+269
+00:19:35,670 --> 00:19:38,970
+اللي قلنا هي عبارة عن الكيوميلاس من الخارج، يليها
+
+270
+00:19:38,970 --> 00:19:42,860
+من الداخلالـ coronal radiata اللي هي عبارة عن
+
+271
+00:19:42,860 --> 00:19:47,140
+تلاتة لأربعة أو من اتنين لتلاتة layer ثم يليها الـ
+
+272
+00:19:47,140 --> 00:19:50,840
+zoonopelucida هذه كلها layer لازم يخترقها الـ
+
+273
+00:19:50,840 --> 00:19:54,300
+sperm عشان يخترقها بيحتاج إلى زيادة ال activity
+
+274
+00:19:54,300 --> 00:19:57,940
+تبعته تحت مصطلح بنسمي high bulb activation
+
+275
+00:19:57,940 --> 00:20:02,460
+fertilization of oocyte normally occur in the
+
+276
+00:20:02,460 --> 00:20:06,820
+umbellarium portion وهي عبارة عن ال upper third of
+
+277
+00:20:06,820 --> 00:20:12,050
+the uterine tube أو الوبيايتوبيعني وين بيصير عملية
+
+278
+00:20:12,050 --> 00:20:16,030
+ال fertilization بتصير في الثلث العلوي من
+
+279
+00:20:16,030 --> 00:20:21,170
+الفلوبيان التيوب استيمتت
+
+280
+00:20:21,170 --> 00:20:25,910
+suggest that sperm return their functional in the
+
+281
+00:20:25,910 --> 00:20:29,250
+female reproductive tract for approximately 37 to
+
+282
+00:20:29,250 --> 00:20:32,770
+80 hours ال sperm طالما وصل للفلوبيان التيوب
+
+283
+00:20:32,770 --> 00:20:36,910
+يستطيع أن يبقى أو فلينا نسميها بشكل عام ال sperm
+
+284
+00:20:36,910 --> 00:20:41,120
+يستطيع أن يملك القدرة على الإخصادويملك ال
+
+285
+00:20:41,120 --> 00:20:43,740
+functional كلمة الخاصة فيه وهو في ال reproductive
+
+286
+00:20:43,740 --> 00:20:49,000
+track الخاصة بال female لمدة تلت أيام لمدة تلت
+
+287
+00:20:49,000 --> 00:20:52,420
+أيام يعني لو صار inter courses جابل .. جابل ال ..
+
+288
+00:20:52,420 --> 00:20:58,940
+ال .. الإبادة بيوم أو بعدها بيوم المفروض ال sperm
+
+289
+00:20:58,940 --> 00:21:02,880
+يكون قادر على التخسيب لأن فترة حياة ال sperm تلت
+
+290
+00:21:02,880 --> 00:21:06,580
+أيام بينما البوايضة يوم واحد عشان كده يقولنا أفضل
+
+291
+00:21:06,580 --> 00:21:11,310
+أوقاتبحدوث ال pregnancy هو حدوث ال interfaces قبل
+
+292
+00:21:11,310 --> 00:21:16,350
+الإبادة بيوم أو يوم الإبادة خلّينا نشوف الفيديو
+
+293
+00:21:16,350 --> 00:21:22,490
+المتعلق بموضوع الcapacitation و الhyperactivation
+
+294
+00:21:22,490 --> 00:21:27,230
+طبعا
+
+295
+00:21:27,230 --> 00:21:31,950
+هذا الفيديو بتكلم عن أكثر من أمر الأمر الأول بتكلم
+
+296
+00:21:31,950 --> 00:21:34,550
+عن الcapacitation و الhyperactivation في نهاية
+
+297
+00:21:34,550 --> 00:21:39,250
+الفيديوبتكلم كيف الكرموزومات الأبوية الخاصة بالـ
+
+298
+00:21:39,250 --> 00:21:42,050
+Male أو الخاصة بال Female بتدمجوا مع بعض البعض و
+
+299
+00:21:42,050 --> 00:21:45,790
+تكون زي God و بتكوّى .. و بتكلم عن الرحلة الصعبة
+
+300
+00:21:45,790 --> 00:21:48,650
+اللتي أمور بيها الـ Spare في الـ Female
+
+301
+00:21:48,650 --> 00:21:52,730
+reproductive tract و ما يقابلها من مخاطر بداية
+
+302
+00:21:52,730 --> 00:21:58,890
+بالـ Low pH مرورا بالـ cervical mucous مرورا بالـ
+
+303
+00:21:58,890 --> 00:22:03,090
+immunological وصولا إلى أول منطقة آمنة وهي ال
+
+304
+00:22:03,090 --> 00:22:09,810
+Fallopian tubeأو الأنابيب خاصة بالرحمة
+
+305
+00:22:09,810 --> 00:22:17,410
+fertilization
+
+306
+00:22:17,410 --> 00:22:20,290
+is the epic story of a single sperm facing
+
+307
+00:22:20,290 --> 00:22:23,670
+incredible odds to unite with an egg and form a
+
+308
+00:22:23,670 --> 00:22:26,870
+new human life it is the story of all of us
+
+309
+00:22:32,330 --> 00:22:35,730
+دuring sexual intercourse about 300 million sperm
+
+310
+00:22:35,730 --> 00:22:40,670
+enter the vagina soon
+
+311
+00:22:40,670 --> 00:22:43,050
+afterward millions of them will either flow out of
+
+312
+00:22:43,050 --> 00:22:49,130
+the vagina or die in its acidic environment أول
+
+313
+00:22:49,130 --> 00:22:53,750
+خطر بواجهه ال spirit بعد ما كان عنده 300 مليون أنه
+
+314
+00:22:53,750 --> 00:22:58,050
+كمية كبيرة جدا منهم بتوفى أو هموت أو بتدمر بفعل ال
+
+315
+00:22:58,050 --> 00:23:01,150
+acidity الخاصة بالفاجينةالـ licensor that we
+
+316
+00:23:01,150 --> 00:23:03,690
+choose however many survive because of the
+
+317
+00:23:03,690 --> 00:23:05,850
+protective elements provided in the fluids
+
+318
+00:23:05,850 --> 00:23:09,350
+surrounding them next the sperm must pass through
+
+319
+00:23:09,350 --> 00:23:13,670
+the cervix and opening into the uterus usually it
+
+320
+00:23:13,670 --> 00:23:16,910
+remains tightly closed but here the cervix is open
+
+321
+00:23:16,910 --> 00:23:20,990
+for a few days while the woman ovulates ينتقل إلى
+
+322
+00:23:20,990 --> 00:23:23,550
+ال cervix من خلال ال opening الخاص بالcervix اللي
+
+323
+00:23:23,550 --> 00:23:26,230
+هي دايما بتكون closed وماتصير لها opening إلا في
+
+324
+00:23:26,230 --> 00:23:31,200
+مرحلة الطبويةالشمس تدخل من خلال ميوكس الشمسيكي
+
+325
+00:23:31,200 --> 00:23:34,880
+اللي كانت مدهشة إلى مستوى ماء أكتر لإيقاف المرحلة
+
+326
+00:23:34,880 --> 00:23:39,200
+الأسهل مرة داخل الشمس الشمسيكية الميوكس الميوكس
+
+327
+00:23:39,200 --> 00:23:44,240
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+328
+00:23:44,240 --> 00:23:44,500
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+329
+00:23:44,500 --> 00:23:44,560
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+330
+00:23:44,560 --> 00:23:44,660
+الميوكس الميوكس الميوكس الميوكس الميوكس الميوكس
+
+331
+00:23:44,660 --> 00:23:56,720
+الميوكس الميوكس الميوكس الميوكس
+
+332
+00:23:56,720 --> 00:23:57,640
+الميوك
+
+333
+00:24:04,790 --> 00:24:08,630
+النظام اللي اخطط السمك لطفولات غريبه تدمر أكتر من
+
+334
+00:24:08,630 --> 00:24:11,810
+الآلاف و أكتر منها تدمر أكتر منها تدمر أكتر منها
+
+335
+00:24:11,810 --> 00:24:16,790
+تدمر أكتر منها تدمر
+
+336
+00:24:16,790 --> 00:24:18,990
+أكتر منها تدمر أكتر منها تدمر أكتر منها تدمر أكتر
+
+337
+00:24:18,990 --> 00:24:19,410
+منها تدمر أكتر منها تدمر أكتر منها تدمر أكتر منها
+
+338
+00:24:19,410 --> 00:24:19,470
+تدمر أكتر منها تدمر أكتر منها تدمر أكتر منها تدمر
+
+339
+00:24:19,470 --> 00:24:19,470
+أكتر منها تدمر أكتر منها تدمر أكتر منها تدمر أكتر
+
+340
+00:24:19,470 --> 00:24:26,570
+منها تدمر أكتر منها تدمر أكتر منها تدمر أكتر منها
+
+341
+00:24:26,570 --> 00:24:30,720
+تدمرInside the fallopian tube, tiny cilia push the
+
+342
+00:24:30,720 --> 00:24:34,500
+egg toward the uterusTo continue, the sperm must
+
+343
+00:24:34,500 --> 00:24:37,920
+surge against this motion to reach the eggSome
+
+344
+00:24:37,920 --> 00:24:41,920
+sperm get trapped in the cilia and dieDuring this
+
+345
+00:24:41,920 --> 00:24:44,380
+part of the journey, chemicals in the reproductive
+
+346
+00:24:44,380 --> 00:24:46,820
+tract cause the membranes covering the heads of
+
+347
+00:24:46,820 --> 00:24:50,000
+the sperm to change حتى بيقوللي في بعض الدراسات
+
+348
+00:24:50,000 --> 00:24:52,380
+بيقولك السيلية الموجودة في ال fallopian tube اللي
+
+349
+00:24:52,380 --> 00:24:56,420
+المفروض يتساعد البويضة على النزولقد تقتل الـ Spare
+
+350
+00:24:56,420 --> 00:25:01,840
+من خلال تعثر الـ Spare .. مش الـ Spare بتعمل كشبكة
+
+351
+00:25:01,840 --> 00:25:05,020
+الـ Spare فبتعمل catching الـ Spare فبالتالي بيخفف
+
+352
+00:25:05,020 --> 00:25:08,540
+و بعمل reduction في الـ Spare count أيضا فبالتالي
+
+353
+00:25:08,540 --> 00:25:12,400
+أصبح الفلوبيري تيوب أيضا البعض النظريات لا تعتبر
+
+354
+00:25:12,400 --> 00:25:16,720
+بيها آمنة okay تعتبر بيها آمنة من حيث ال oxidative
+
+355
+00:25:16,720 --> 00:25:21,290
+stress من حيث ال pHمن حيث مافيه end immune system،
+
+356
+00:25:21,290 --> 00:25:24,990
+من حيث مافيه end mucus أوكي مافيش مشكلة بسميها
+
+357
+00:25:24,990 --> 00:25:29,790
+safe environment، ولكن من حيث السيليا، لاتعتبر
+
+358
+00:25:29,790 --> 00:25:34,410
+safe As a result, the sperm become hydroactive,
+
+359
+00:25:34,870 --> 00:25:36,950
+swimming harder and faster toward their
+
+360
+00:25:36,950 --> 00:25:42,050
+destination At long last, the sperm reach the egg
+
+361
+00:25:45,390 --> 00:25:47,410
+فقط عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+362
+00:25:47,410 --> 00:25:49,070
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+363
+00:25:49,070 --> 00:25:50,130
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+364
+00:25:50,130 --> 00:25:53,770
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+365
+00:25:53,770 --> 00:25:53,850
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+366
+00:25:53,850 --> 00:25:54,150
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+367
+00:25:54,150 --> 00:25:55,470
+عشان عشان عشان عشان عشان عشان عشان عشان عشان عشان
+
+368
+00:25:55,470 --> 00:25:59,490
+عشان عشان عشان عشان عشان
+
+369
+00:26:18,170 --> 00:26:20,650
+بالداخل من المنطقة الـ Pelucida يوجد مكان مليء
+
+370
+00:26:20,650 --> 00:26:26,050
+بالطبقات المطلوبة فقط خارج ممكنات الطفولة الأول
+
+371
+00:26:26,050 --> 00:26:31,050
+ممكن أن يتواصل معها سوف تفيرتليفي الطفولة بعد
+
+372
+00:26:31,050 --> 00:26:35,790
+مهارة غير قوية وعن أعظم فرصة واحدة من الطفولة تقع
+
+373
+00:26:35,790 --> 00:26:40,530
+في ممكنات الطفولة خلال عدة دقيقة من الوقت ممكنات
+
+374
+00:26:40,530 --> 00:26:43,310
+الطفولة الخارجية تتجمد وطفولة الطفولة تدخل فيها
+
+375
+00:26:43,310 --> 00:26:48,120
+هذا الحدث يسبب في تغييرات في ممكنات الطفولةthat
+
+376
+00:26:48,120 --> 00:26:52,200
+prevent other sperm from attaching to it تحكيلي
+
+377
+00:26:52,200 --> 00:26:55,740
+بعد اختراق أول sperm للcell membrane الخاصة
+
+378
+00:26:55,740 --> 00:26:59,380
+بالزونابلوسيدا بيتم حجز هذا ال sperm في الداخل
+
+379
+00:26:59,380 --> 00:27:04,120
+وتغيير التركيب الكيميائي الخاص بالزونابلوسيدا لمنع
+
+380
+00:27:04,120 --> 00:27:08,420
+دخول أي sperm آخر عشان كده البويضة لا تلقح إلا ب
+
+381
+00:27:08,420 --> 00:27:11,820
+single sperm اللذي يلقح اللذي يلقح البويضة هو
+
+382
+00:27:11,820 --> 00:27:17,500
+الأسرع والذي يصل بشكل أسرعفبالتالي لا يوجد بويضة
+
+383
+00:27:17,500 --> 00:27:21,360
+تُلقّح بأكثر من الـ sperm لا يوجد بويضة تُلقّح
+
+384
+00:27:21,360 --> 00:27:24,940
+بأكثر من الـ sperm لعدة أسباب هتتكلم عنها أولها
+
+385
+00:27:24,940 --> 00:27:28,520
+تغيير التركيب الكيميائي للـ receptor و خاص بيه على
+
+386
+00:27:28,520 --> 00:27:31,900
+سطح الـ zoonocyte خاص بالـ sperm Next, the egg
+
+387
+00:27:31,900 --> 00:27:34,500
+releases chemicals that push other sperm away from
+
+388
+00:27:34,500 --> 00:27:37,400
+the egg and create an impenetrable fertilization
+
+389
+00:27:37,400 --> 00:27:41,620
+membrane السبب التاني أن البويضة نفسها بعد عملية
+
+390
+00:27:41,620 --> 00:27:44,550
+ال fertilization تبدأ تفرز مواد كيميائيةتعمل
+
+391
+00:27:44,550 --> 00:27:48,430
+elimination أو طرد للـ sperm فتمنعه من عملية الـ
+
+392
+00:27:48,430 --> 00:27:51,390
+penetration as the reaction spreads outward the
+
+393
+00:27:51,390 --> 00:27:54,510
+zona pellucida hardens trapping any sperm unlucky
+
+394
+00:27:54,510 --> 00:27:59,750
+enough to be caught inside outside
+
+395
+00:27:59,750 --> 00:28:02,850
+the egg sperm are no longer able to attach to the
+
+396
+00:28:02,850 --> 00:28:07,610
+zona pellucida ال zona pellucida أيضا أصبحت very
+
+397
+00:28:07,610 --> 00:28:10,790
+hard فبالتالي ال sperm مش هيقدر يخترقها يعني تلت
+
+398
+00:28:10,790 --> 00:28:16,340
+أسباب تمنعتلقيح البوايضة بأكثر من الـ sperm بمجرد
+
+399
+00:28:16,340 --> 00:28:19,720
+دخول one sperm أو first sperm للبوايضة البوايضة
+
+400
+00:28:19,720 --> 00:28:23,660
+بتغير ال receptor الخاصة بـ spermatozoon مولودة
+
+401
+00:28:23,660 --> 00:28:26,920
+على سطحها بتصير الـ zoonablecida أكثر صلابة
+
+402
+00:28:26,920 --> 00:28:29,840
+البوايضة بتفرز بعض المواد الكيميائية اللي بتعمل
+
+403
+00:28:29,840 --> 00:28:35,760
+elimination لل sperm meanwhile inside the egg the
+
+404
+00:28:35,760 --> 00:28:38,560
+tightly packed male genetic material spreads out
+
+405
+00:28:40,790 --> 00:28:44,610
+تنظيم جديد يتطور حول المادة الجنية ويصنع الـ
+
+406
+00:28:44,610 --> 00:28:49,350
+Pronucleus الرجل في الداخل، المادة الجنية تتطور
+
+407
+00:28:49,350 --> 00:28:53,610
+مرة أخرى إلى 23 كرموزومتين المادة الجنية الفتاة
+
+408
+00:28:53,610 --> 00:28:56,710
+تتطور بمعالجة التعزيز من الزبدة مع الزبدة التي
+
+409
+00:28:56,710 --> 00:28:57,570
+تنتهي في المزيد من المزيد من المزيد من المزيد من
+
+410
+00:28:57,570 --> 00:29:00,130
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+411
+00:29:00,130 --> 00:29:01,570
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+412
+00:29:01,570 --> 00:29:01,950
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+413
+00:29:01,950 --> 00:29:03,130
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+414
+00:29:03,130 --> 00:29:04,490
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+415
+00:29:04,490 --> 00:29:05,650
+المزيد
+
+416
+00:29:09,770 --> 00:29:14,250
+واتجههم إلى بعضهم البعض الانتجارات الانتجارات
+
+417
+00:29:14,250 --> 00:29:17,710
+الانتجارات تتجمع مع بعضها البعض تكمل عملية التنمية
+
+418
+00:29:17,710 --> 00:29:22,370
+في هذه اللحظة تتجه موضوع كودة جينيكي مميز للجنس
+
+419
+00:29:22,370 --> 00:29:25,910
+بسرعة تقوم بتحديد جمهورية، ورقم العيون، ورقم
+
+420
+00:29:25,910 --> 00:29:29,910
+العيون، ومئات أخرى شخصية مختلفة. هذا الجلد
+
+421
+00:29:29,910 --> 00:29:32,730
+الانتجاري الانتجاري الانتجاري الانتجاري الانتجاري
+
+422
+00:29:32,730 --> 00:29:33,210
+الانتجاري الانتجاري الانتجاري الانتجاري الانتجاري
+
+423
+00:29:33,210 --> 00:29:36,840
+الانتجاري الانتجاريAnd now the cilia in the
+
+424
+00:29:36,840 --> 00:29:39,900
+fallopian tube gently sweep the zygote toward the
+
+425
+00:29:39,900 --> 00:29:42,720
+uterus, where he or she will implant in the rich
+
+426
+00:29:42,720 --> 00:29:45,840
+uterine lining, growing and maturing for the next
+
+427
+00:29:45,840 --> 00:29:51,000
+nine months until ready for birth هذه
+
+428
+00:29:51,000 --> 00:29:54,680
+عبارة عن رحلة تدخل ال sperm خلال ال female
+
+429
+00:29:54,680 --> 00:29:58,440
+reproductive tract وصولا إلى القنوات التي لها
+
+430
+00:29:58,440 --> 00:30:03,730
+علاقة بالميبياأو القنوات fallopian tube التي لها
+
+431
+00:30:03,730 --> 00:30:09,170
+علاقة بعملية التوقيح حيث تحدث في الثلث الأعلى من
+
+432
+00:30:09,170 --> 00:30:13,770
+fallopian tube أعرفنا كيف بتم عملية نقل ال sperm
+
+433
+00:30:13,770 --> 00:30:18,930
+إيش أهم ال action اللي بتصير على ال sperm مجرد
+
+434
+00:30:18,930 --> 00:30:23,210
+وصوله لل fallopian tube تحت مصطلح capacitation و
+
+435
+00:30:23,210 --> 00:30:27,450
+hyperactivation تحت مصطلح capacitation و
+
+436
+00:30:27,450 --> 00:30:34,480
+hyperactivationهنتقف عن هذا الحد في محاضرة اليوم،
+
+437
+00:30:34,480 --> 00:30:38,320
+على أمل أن نلتقي في محاضرة قادمة ان شاء الله،
+
+438
+00:30:38,320 --> 00:30:40,780
+دومتم بخير وفي حفظ الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/1ufMvFV5K5U.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/1ufMvFV5K5U.srt
new file mode 100644
index 0000000000000000000000000000000000000000..b212369b2ce8d4b921e3debf8a27a4e22bfaa495
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/1ufMvFV5K5U.srt
@@ -0,0 +1,1827 @@
+1
+00:00:00,890 --> 00:00:05,230
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,230 --> 00:00:11,250
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين، طلابنا 
+
+3
+00:00:11,250 --> 00:00:16,490
+الأعزاء، أرجو من الله الكريم أن تكونوا جميعا بخير و
+
+4
+00:00:16,490 --> 00:00:22,890
+بصحة جيدة. اليوم سوف ننتقل إلى موضوع جديد يكمل ما
+
+5
+00:00:22,890 --> 00:00:28,870
+سبقه من مواضيع خاصة لمساق التلقيح الصناعي، طرقه 
+
+6
+00:00:28,870 --> 00:00:34,620
+وأساليبه. الموضوع اليوم يتحدث عن  الـ ICSI وهو عبارة
+
+7
+00:00:34,620 --> 00:00:40,660
+عن اختصار لكلمة يُقصد بها Intracytoplasmic sperm 
+
+8
+00:00:40,660 --> 00:00:46,140
+injection، يعني الحقن المجهري باستخدام حيوان منوي
+
+9
+00:00:46,140 --> 00:00:51,060
+واحد. سنتكلم في هذا الـ chapter عن عدة أمور منها
+
+10
+00:00:51,060 --> 00:00:56,020
+الآلية المستخدمة في القبض على الحيوان المنوي تحت 
+
+11
+00:00:56,020 --> 00:00:59,600
+مصطلح Spermatozoa Catching or Catching of
+
+12
+00:00:59,600 --> 00:01:04,300
+Spermatozoa. مصطلح إعطاب الحيوان المنوي وفقدان 
+
+13
+00:01:04,300 --> 00:01:08,360
+القدرة على الحركة من خلال مصطلح بنسميه sperm
+
+14
+00:01:08,360 --> 00:01:12,860
+immobilization. بعدين ننتقل إلى الميكروسكوب الذي
+
+15
+00:01:12,860 --> 00:01:17,360
+يستخدم في الحقن المجهري. ننتقل للتحدث عن الـ media
+
+16
+00:01:17,360 --> 00:01:21,980
+التي تقلل من حركة الحيوان المنوي. ننتقل إلى آلية 
+
+17
+00:01:21,980 --> 00:01:27,100
+الحقن. ثم نتدرج فيما بعد إلى تطور الجنين منذ لحظة
+
+18
+00:01:27,100 --> 00:01:32,660
+حقن الحيوان المنوي حتى لحظة الإرجاع داخل رحم سيدة
+
+19
+00:01:32,660 --> 00:01:38,540
+بداية عندما نقول ICSI هي عبارة عن كلمة مكونة من
+
+20
+00:01:38,540 --> 00:01:45,160
+أربع حروف، الحرف الأول I-C-S-I وهي اختصار
+
+21
+00:01:45,160 --> 00:01:49,820
+للـ Intracytoplasmic sperm injection، يعني حقن
+
+22
+00:01:49,820 --> 00:01:56,490
+الحيوان داخل الـ cytoplasm. وهذه العملية تشمل اختيار
+
+23
+00:01:56,490 --> 00:02:01,170
+single sperm وعمل insertion لهذا الـ sperm داخل الـ
+
+24
+00:02:01,170 --> 00:02:06,050
+oocyte، بشرط أن تكون هذه الخلية أو هذه البويضة
+
+25
+00:02:06,050 --> 00:02:11,930
+ناضجة، أي هي عبارة عن بويضة استقرت في الـ metaphase
+
+26
+00:02:11,930 --> 00:02:17,010
+الخاص بالانقسام الميوزي الثاني. By passing all the
+
+27
+00:02:17,010 --> 00:02:21,630
+egg coat penetration and gamete fusion step
+
+28
+00:02:22,000 --> 00:02:26,460
+characterized of natural fertilization. من خلال
+
+29
+00:02:26,460 --> 00:02:30,200
+اختراق جميع الأغلفة المحيطة بالبويضة ووصول إلى
+
+30
+00:02:30,200 --> 00:02:33,300
+الـ cytoplasm. يتم إطلاق الحيوان المنوي في 
+
+31
+00:02:33,300 --> 00:02:36,960
+الـ cytoplasm الخاص بالبويضة، مما يسمح باندماج
+
+32
+00:02:36,960 --> 00:02:41,020
+النواة الذكرية مع النواة الأنثوية لتكوين خلية
+
+33
+00:02:41,020 --> 00:02:45,500
+جديدة. هذه العملية بالمجمل تسمى الإخصاب أو الـ
+
+34
+00:02:45,500 --> 00:02:49,540
+fertilization. أول ما تم إنشاء الـ ICSI كان على الـ
+
+35
+00:02:49,540 --> 00:02:54,260
+rabbit بشكل أساسي. وأول عملية تم فيها استخدامها للـ
+
+36
+00:02:54,260 --> 00:02:58,040
+human gamete كانت وادت طبعا إلى حدوث الـ pregnancy
+
+37
+00:02:58,040 --> 00:03:03,900
+كانت حوالي فيها بداية عام 1992. ثم بعد ذلك توالت
+
+38
+00:03:03,900 --> 00:03:09,180
+الحالات وتوالى إنجاب أطفال باستخدام خاصية الحقن
+
+39
+00:03:09,180 --> 00:03:15,740
+المجهري أو تقنية الحقن المجهري اللي اسمها ICSI. The
+
+40
+00:03:15,740 --> 00:03:18,700
+technique was developed to help achieve the
+
+41
+00:03:18,700 --> 00:03:22,840
+fertilization for couples. لمين الـ couples؟ أو هل
+
+42
+00:03:22,840 --> 00:03:26,340
+التقنية تساعد مين؟ تساعد الـ couples اللي عندهم 
+
+43
+00:03:26,340 --> 00:03:31,380
+مشكلة في الـ infertility وبكون سبب هذه المشكلة male
+
+44
+00:03:31,380 --> 00:03:35,580
+بشكل أساسي أو الـ couples اللي عندهم مشكلة في 
+
+45
+00:03:35,580 --> 00:03:40,860
+الحصول على بويضة ملقحة أو تلقيح البويضة بشكلها
+
+46
+00:03:40,860 --> 00:03:45,460
+الطبيعي، وهي عبارة عن الحاجة بتسميها in vivo
+
+47
+00:03:45,460 --> 00:03:48,940
+fertilization. يعني عند two couples عندهم مشكلة في 
+
+48
+00:03:48,940 --> 00:03:53,170
+التلقيح الطبيعي أو two couples مشكلتهم خاصة بالميل
+
+49
+00:03:53,170 --> 00:03:58,490
+وهذه المشكلة بتكون في مراحل متقدمة بشكل كبير جدا
+
+50
+00:03:58,490 --> 00:04:05,090
+طبعا متى نلجأ إلى الـ ICSI؟ بشكل عام إذا كان عندي ما 
+
+51
+00:04:05,090 --> 00:04:09,550
+يقارب من حيث الـ semen parameter عدد الـ sperm أو الـ
+
+52
+00:04:09,550 --> 00:04:13,210
+concentration of sperm ما توزع في الـ semen fluid
+
+53
+00:04:13,210 --> 00:04:18,910
+أقل من 5 مليون sperm per milliliter ساعتها هذه
+
+54
+00:04:18,910 --> 00:04:24,710
+الحالة يمكن أن تستخدم إلى الـ ICSI أو الـ IVF، ولكن 
+
+55
+00:04:24,710 --> 00:04:29,530
+بشكل عام كل ما قل عدد الـ sperm كل ما قل عدد الـ
+
+56
+00:04:29,530 --> 00:04:34,530
+sperm المتحرك، نميل إلى استخدام الـ ICSI أفضل من الـ
+
+57
+00:04:34,530 --> 00:04:38,490
+IVF. So, likelihood of fertilization with a
+
+58
+00:04:38,490 --> 00:04:41,990
+standard IVF is significantly reduced and
+
+59
+00:04:41,990 --> 00:04:45,030
+therefore such couples should be considered
+
+60
+00:04:45,030 --> 00:04:49,090
+unstable for this procedure particularly where
+
+61
+00:04:49,090 --> 00:04:53,590
+less than 1% normal form while we are observed
+
+62
+00:04:53,590 --> 00:04:57,370
+يعني إذا كان عندي عدد الحيوانات المنوية الموجودة
+
+63
+00:04:57,370 --> 00:05:02,550
+في العينة أقل من 5 مليون، نميل إلى الـ IVF. كل ما قل ..
+
+64
+00:05:02,550 --> 00:05:06,250
+كل ما قل عدد الحيوانات المنوية كل ما قل عدد
+
+65
+00:05:06,250 --> 00:05:10,890
+الحيوان المنوي المتحرك، نلجأ إلى الـ ICSI فبالتالي 
+
+66
+00:05:10,890 --> 00:05:15,730
+بشكل مجمل إذا كان عندك كمية الـ motile كمية قليلة
+
+67
+00:05:15,730 --> 00:05:20,870
+جدا جدا تكاد تعاد على أصابع يد الواحدة أو تعاد
+
+68
+00:05:20,870 --> 00:05:24,550
+بشكل مئات فقط لا غير ولا تصل إلى آلاف أو مئات
+
+69
+00:05:24,550 --> 00:05:28,720
+الآلاف ساعتها هذه الـ couples وهذه الـ case تروح إلى
+
+70
+00:05:28,720 --> 00:05:34,020
+الحقن المجهري ولا تذهب إلى التلقيح الصناعي المسمى
+
+71
+00:05:34,020 --> 00:05:38,420
+بالـ IVF. However, fertilization of mature oocyte
+
+72
+00:05:38,420 --> 00:05:42,760
+may still fail to occur in the presence of normal
+
+73
+00:05:42,760 --> 00:05:47,520
+sperm because of hardening or very hard
+
+74
+00:05:47,520 --> 00:05:51,880
+zona pellucida or when oocyte revival or plasma
+
+75
+00:05:51,880 --> 00:05:57,110
+membrane inclusion. بعض الأحيان بيكون عندي الـ cytoplasm
+
+76
+00:05:57,110 --> 00:06:01,110
+بيكون عنده عدد الحيوانات المنوية طبيعي بشكل أو
+
+77
+00:06:01,110 --> 00:06:06,950
+بآخر، ولكن تفشل عملية التلقيح بسبب ما يلي. السبب
+
+78
+00:06:06,950 --> 00:06:09,470
+الأول أن يكون فيها zona pellucida very hard
+
+79
+00:06:09,470 --> 00:06:13,430
+فيصعب على الـ sperm أن يخترقها بطريقة التلقيح
+
+80
+00:06:13,430 --> 00:06:17,290
+الطبيعي أو طريقة التلقيح في المختبر ما يعرف باسم
+
+81
+00:06:17,290 --> 00:06:21,330
+الـ IVF. بخلاف الـ ICSI الـ IVF أنا بخلي الجميط مع 
+
+82
+00:06:21,330 --> 00:06:25,010
+بعض وبعض الـ oocyte مع الـ sperm وبتيح الفرصة للـ
+
+83
+00:06:25,010 --> 00:06:29,270
+sperm أن يخترق البويضة. بس في الـ ICSI أنا اللي بخترق
+
+84
+00:06:29,270 --> 00:06:32,950
+البويضة وبدخل الـ sperm من خلال الـ needle. في بعض
+
+85
+00:06:32,950 --> 00:06:36,430
+الأحيان بيكون عندي الـ normal semen parameter
+
+86
+00:06:36,430 --> 00:06:39,780
+normal أو الـ semen parameter as normal، بارامترات 
+
+87
+00:06:39,780 --> 00:06:44,920
+ولكن يفشل الـ sperm في عملية التلقيح بسبب زيادة في
+
+88
+00:06:44,920 --> 00:06:49,960
+صعوبة اختراق البويضة أو فقدان الـ sperm القدرة في
+
+89
+00:06:49,960 --> 00:06:54,700
+اختراق البويضة بسبب زيادة الـ thickness تبع
+
+90
+00:06:54,700 --> 00:06:58,280
+الـ zona pellucida أو الصلابة. الشغل التاني أن يكون
+
+91
+00:06:58,280 --> 00:07:01,920
+الـ cytoplasm of oocyte يحتوي على بعض الـ inclusion
+
+92
+00:07:01,920 --> 00:07:05,820
+body التي تعيق الـ Spermatozoa من عملية الاختراق 
+
+93
+00:07:05,820 --> 00:07:08,940
+لأنّ abnormalities في الـ zona pellucida أكيد بتعمل
+
+94
+00:07:08,940 --> 00:07:11,700
+الـ prevention و preventing للـ sperm fusion
+
+95
+00:07:11,700 --> 00:07:17,280
+فبالتالي يصعب عملية الاختراق أيضًا. منها الـ sperm
+
+96
+00:07:17,280 --> 00:07:21,040
+may not move in normal fusion. الـ sperm ما بتتحرك
+
+97
+00:07:21,040 --> 00:07:24,630
+بالشكل الطبيعي، فبالتالي ما بيخترق بالشكل الطبيعي أو
+
+98
+00:07:24,630 --> 00:07:27,810
+الـ sperm عنده troubleshooting في عملية الـ
+
+99
+00:07:27,810 --> 00:07:31,110
+attachment مع الـ receptor الموجودة على الـ egg
+
+100
+00:07:31,110 --> 00:07:36,290
+فبالتالي هذه الأمور، الصلابة في الـ zona pellucida، وجود
+
+101
+00:07:36,290 --> 00:07:39,430
+inclusion body في الـ cytoplasm الخاص بالـ oocyte
+
+102
+00:07:39,430 --> 00:07:43,870
+وجود خطأ في حركة الحيوان المنوي أو حركة الحيوان
+
+103
+00:07:43,870 --> 00:07:49,710
+المنوي الغير طبيعية، أيضا وجود فشل في اتصال وارتباط
+
+104
+00:07:49,710 --> 00:07:54,660
+الحيوان المنوي بالـ oocyte. هذه الأمور تؤدي إلى فشل 
+
+105
+00:07:54,660 --> 00:08:01,020
+عملية التلقيح الصناعي المعروف بالـ IVF. لذلك نلجأ
+
+106
+00:08:01,020 --> 00:08:05,460
+إلى الـ ICSI أيضًا. الـ ICSI مهم جدًا في الأشخاص
+
+107
+00:08:05,460 --> 00:08:10,480
+المصابين بالـ HIV أو الأشخاص المصابين بالـ 
+
+108
+00:08:10,480 --> 00:08:15,420
+Hepatitis C Viral. الناس المصابة بالـ HIV ما بتقدر
+
+109
+00:08:15,420 --> 00:08:19,400
+تنجب بشكل طبيعي. هي بتنجب بشكل طبيعي، ولكن ما بتقدر 
+
+110
+00:08:19,400 --> 00:08:24,380
+تنجب baby طبيعي خالي من المرض. فبتلجأ إلى التلقيح
+
+111
+00:08:24,380 --> 00:08:28,340
+الصناعي عشان يعمل عملية filtration وعملية washing
+
+112
+00:08:28,340 --> 00:08:32,760
+للـ spermatozoa والتخلص من كل الـ antigens اللي لها 
+
+113
+00:08:32,760 --> 00:08:37,520
+علاقة بالـ HIV فبحصل على single sperm pure بحقنه في 
+
+114
+00:08:37,520 --> 00:08:41,380
+البويضة علشان أمنع انتقال هذا المرض. Finally,
+
+115
+00:08:41,600 --> 00:08:46,520
+because only single spermatozoa is needed for each
+
+116
+00:08:46,520 --> 00:08:50,180
+egg, ICSI has allowed the treatment of men who
+
+117
+00:08:50,180 --> 00:08:57,780
+are suffering from azoospermia. أيضًا بعض الـ male
+
+118
+00:08:57,780 --> 00:09:01,120
+بيعانوا من حالة بنسميها azoospermia وهذه الـ
+
+119
+00:09:01,120 --> 00:09:05,530
+azoospermia عرفنا تعريفها في مصطلح بمعنى آخر عنده
+
+120
+00:09:05,530 --> 00:09:09,450
+كمية قليلة جدا جدا جدا من عدد الحيوانات المنوية
+
+121
+00:09:09,450 --> 00:09:13,250
+تكاد تكون معدومة. فبالتالي single sperm لو أنا
+
+122
+00:09:13,250 --> 00:09:16,970
+وجدته في العينة يكفي لإنجاح حملة الحقن المجهري
+
+123
+00:09:16,970 --> 00:09:22,110
+فبالتالي بلجأ إلى البحث في العينة عن طريق الـ TESA
+
+124
+00:09:22,110 --> 00:09:25,470
+أو الـ PESA. الـ blockage في الـ main reproductive
+
+125
+00:09:25,470 --> 00:09:29,710
+tract may keep sperm from getting out. فبالتالي
+
+126
+00:09:29,710 --> 00:09:34,660
+بلجأ إلى الـ PESA أو الـ TESA. البدء في استخدام الـ
+
+127
+00:09:34,660 --> 00:09:37,880
+Immature Oocyte لأنّ الـ Immature Oocyte يمكن
+
+128
+00:09:37,880 --> 00:09:41,620
+أن ينضج في المختبر فيصبح mature، عندئذ أستطيع
+
+129
+00:09:41,620 --> 00:09:46,180
+استخدامها في عملية الحقن المجهري. أيضًا الـ oocyte
+
+130
+00:09:46,180 --> 00:09:50,680
+الزائدة عن الحاجة ممكن سيدة بعد الـ response يصير
+
+131
+00:09:50,680 --> 00:09:54,520
+عندها very high فتعطيني 35 بويضة. مش منطقي ألقح الـ
+
+132
+00:09:54,520 --> 00:09:58,240
+35 بويضة بشكل كامل لأنّ مش هقدر أرجع إلى maximum
+
+133
+00:09:58,240 --> 00:10:03,150
+خمس أجنة. أفضل خمس أجنة. فبروح بخزن هذه البويضات
+
+134
+00:10:03,150 --> 00:10:08,830
+الزائدة إلى الـ next cycle فبحمي السيدة من عملية
+
+135
+00:10:08,830 --> 00:10:12,270
+الـ stimulation التالية، فبالتالي بقل العدد وكمية
+
+136
+00:10:12,270 --> 00:10:15,490
+الهرمونات والحقن التي تتناولها السيدة من خلال 
+
+137
+00:10:15,490 --> 00:10:20,450
+استخدام الـ oocyte المجمدة. طبعًا هذا كله أعطاني
+
+138
+00:10:20,450 --> 00:10:26,430
+فرصة لاستخدام الـ ICSI بدلاً عن الـ IVF. الـ ICSI
+
+139
+00:10:26,430 --> 00:10:32,260
+procedure بشكل عام تحتاج إلى Male و Female. الـ male
+
+140
+00:10:32,260 --> 00:10:34,720
+بيخضع لـ الـ Sample Collection ثم الـ Sample 
+
+141
+00:10:34,720 --> 00:10:37,040
+Preparation Sample Collection ثم Sample
+
+142
+00:10:37,040 --> 00:10:42,120
+Preparation علشان احصل على الـ Pure Spermatozoa من
+
+143
+00:10:42,120 --> 00:10:47,200
+خلال الـ Gradient من خلال الـ Simple Dilution أو 
+
+144
+00:10:47,200 --> 00:10:50,520
+من خلال الـ Swim Up أما في المايل بيخضع على
+
+145
+00:10:50,520 --> 00:10:54,420
+برنامج خاص بيسميه Ovarian Stimulation أو Ovarian
+
+146
+00:10:54,420 --> 00:10:57,640
+Hyperstimulation أو Ovarian أو Controlled Ovarian
+
+147
+00:10:57,640 --> 00:11:02,800
+Stimulation حقنها بأنواع معينة من الهرمونات من أجل
+
+148
+00:11:02,800 --> 00:11:07,420
+زيادة استجابة المبيض لهذه الهرمونات مما يؤدي إلى
+
+149
+00:11:07,420 --> 00:11:12,900
+إخراج بويضات أكثر من حيث العدد إخراج بويضات أكثر 
+
+150
+00:11:12,900 --> 00:11:16,980
+من حيث النضوج فبالتالي بيصير عندي فرصة أكثر وأكبر
+
+151
+00:11:16,980 --> 00:11:21,870
+لحقن أكبر عدد من البويضات The semen sample is
+
+152
+00:11:21,870 --> 00:11:24,830
+prepared by centrifugation. The sperm should be
+
+153
+00:11:24,830 --> 00:11:27,850
+collected in special media. The separated sperm
+
+154
+00:11:27,850 --> 00:11:30,990
+should be separated from the live sperm from
+
+155
+00:11:30,990 --> 00:11:34,990
+depressed and most dead sperm هذه الـ Spermatozoa
+
+156
+00:11:34,990 --> 00:11:38,050
+اللي عملت لها عملية purification و washing لازم ال
+
+157
+00:11:38,050 --> 00:11:41,410
+live sperm والذي يستخدم في عملية الحقن المجهري
+
+158
+00:11:41,410 --> 00:11:45,530
+أفصلوا بشكل كامل عن كل ال depressed الموجودة وعن
+
+159
+00:11:45,530 --> 00:11:49,170
+كل ال dead sperm الموجودة عن كل ال immature sperm
+
+160
+00:11:49,170 --> 00:11:53,070
+الموجودة اللي سمناها Spermato-Spermated فيما سابق
+
+161
+00:11:53,070 --> 00:11:56,510
+الـ Embryologists فيما بعد وظيفته انه يعمل
+
+162
+00:11:56,510 --> 00:12:00,670
+catching أو pick up لل single live sperm ويعمله
+
+163
+00:12:00,670 --> 00:12:06,310
+عملية injection داخل البويضة علشان كده عملية الحقن
+
+164
+00:12:06,310 --> 00:12:10,850
+تحتاج الى two arms واحد اسمه holder بيبت holder
+
+165
+00:12:10,850 --> 00:12:14,610
+بيحمل فيه الـ pipette بيحمل فيه عفوا الـ oocyte وبيكون 
+
+166
+00:12:14,610 --> 00:12:18,530
+على اليسار في الغالب و injection needle بتكون على
+
+167
+00:12:18,530 --> 00:12:22,990
+اليمين في الغالب كلهم mainly glass واحدة بتثبت
+
+168
+00:12:22,990 --> 00:12:27,730
+البويضة واحدة بتحمل الـ sperm وبتعمل injection في
+
+169
+00:12:27,730 --> 00:12:32,110
+داخل البويضة هنشوفها بالصورة إن شاء الله جاب
+
+170
+00:12:32,110 --> 00:12:36,050
+المبدأ في عملية ال catching أو ال pick up of
+
+171
+00:12:36,050 --> 00:12:39,910
+spermatozoa في المحاضرات السابقة تكلمنا عن ال
+
+172
+00:12:39,910 --> 00:12:42,970
+semen parameter تكلمنا عن ال semen collection
+
+173
+00:12:42,970 --> 00:12:46,370
+تكلمنا عن ال purification method التلات أقسام 
+
+174
+00:12:46,370 --> 00:12:51,820
+حالياً العينة وصلتني كمختبر embryologist as
+
+175
+00:12:51,820 --> 00:12:58,400
+spermatozoa pure يعني sperm live متحرك يصلح لعملية
+
+176
+00:12:58,400 --> 00:13:01,980
+الـ IVF أو عملية الحقن الـ ICSI احنا بنتكلم عن ال
+
+177
+00:13:01,980 --> 00:13:06,060
+ICSI عشان أتم عملية الـ ICSI لازم ابدأ بعملية
+
+178
+00:13:06,060 --> 00:13:10,080
+مهمة جدا اسمها ICSI dish preparation كيف يتم 
+
+179
+00:13:10,080 --> 00:13:13,480
+تحضير أطباق الحقن الـ majority طبق الحقن ال
+
+180
+00:13:13,480 --> 00:13:18,200
+majority هو طبق very sterile dish يشبه إلى حد ما
+
+181
+00:13:18,200 --> 00:13:22,180
+الأطباق الخاصة بالـ Microbiology ولكن أصغر من حيث 
+
+182
+00:13:22,180 --> 00:13:27,780
+الحجم تكون معقمة بشكل كامل لا تستخدم ولا تفتح إلا
+
+183
+00:13:27,780 --> 00:13:32,540
+عند الاستخدام رغم أن بعض الدراسات تقولك يجب فتح ال
+
+184
+00:13:32,540 --> 00:13:37,040
+bucket الخاص بالـ dish الـ ICSI dish علشان يطلع منها 
+
+185
+00:13:37,040 --> 00:13:41,160
+الـ volatile gas لأن بقاءه بيأثر سلبا على الجنين
+
+186
+00:13:41,160 --> 00:13:45,020
+فماشي بنفتحها وبنخليها في درج وفي مكان معقم وعند
+
+187
+00:13:45,020 --> 00:13:48,430
+الحاجة بناخد الطبق في sterile condition، sterile
+
+188
+00:13:48,430 --> 00:13:52,870
+media، داخل الـ safety cabinet نضع داخل الطبق تمان
+
+189
+00:13:52,870 --> 00:13:57,210
+قطرات أو تسع قطرات، في الغالب تسع قطرات تمانية على
+
+190
+00:13:57,210 --> 00:14:02,210
+المحيط وواحدة في المنتصف فبالتالي، nine drops
+
+191
+00:14:02,210 --> 00:14:05,790
+contained eight microliter of injection media are
+
+192
+00:14:05,790 --> 00:14:09,210
+replaced in the Petri dish with one in the center
+
+193
+00:14:09,210 --> 00:14:13,830
+and the rest around this drop يعني بمعنى أخر باخد
+
+194
+00:14:13,830 --> 00:14:16,470
+ثمانية microliter وبعض الأحيان عشرة microliter
+
+195
+00:14:16,470 --> 00:14:21,710
+بضع تسع نقاط واحدة في المنتصف وثمانية حولها كل
+
+196
+00:14:21,710 --> 00:14:25,290
+نقطة فيها من ثمانية لعشرة microliter من ال
+
+197
+00:14:25,290 --> 00:14:30,230
+injection media طب ليش حطيت نقطة في المنتصف؟ وإيش 
+
+198
+00:14:30,230 --> 00:14:34,210
+وظيفة الثمانية الموجودة على الحواف؟ الثمانية
+
+199
+00:14:34,210 --> 00:14:38,610
+الموجودة على الدائرة والحواف هي المسئولة عن أو
+
+200
+00:14:38,610 --> 00:14:42,440
+المكان الذي سوف نضع فيه البوايضات بعد عملية ال
+
+201
+00:14:42,440 --> 00:14:45,500
+Denudation اللي أخدناها فيه من قبل أما القطرة
+
+202
+00:14:45,500 --> 00:14:49,000
+الموجودة في المنتصف هي التي سنحمل فيها ال
+
+203
+00:14:49,000 --> 00:14:53,500
+spermatozoa فبالتالي بصير هندي 8 قطرات لو وضعت في
+
+204
+00:14:53,500 --> 00:14:57,180
+كل قطرة بويضة هي 8 بوايضات في كل قطرة بويضتين هي 
+
+205
+00:14:57,180 --> 00:15:01,240
+16 بويضة وقطرة في المنتصف تحتوي على ال
+
+206
+00:15:01,240 --> 00:15:05,380
+spermatozoa التي سوف تستخدم في عملية الحقن ال
+
+207
+00:15:05,380 --> 00:15:09,600
+drops should be close together في فترة المسافة بينهم
+
+208
+00:15:09,600 --> 00:15:13,740
+لا تتجاوز الـ 20 ميلي متر لتسهيل عملية الانتقال من 
+
+209
+00:15:13,740 --> 00:15:17,520
+قطرة إلى قطرة ولازم تكون على heat stage درجة
+
+210
+00:15:17,520 --> 00:15:22,420
+حرارته وليس في درجة حرارة جسم الإنسان 37 the
+
+211
+00:15:22,420 --> 00:15:27,300
+drops should be then overlaid with oil to prevent
+
+212
+00:15:27,300 --> 00:15:31,600
+evaporation طبعا بعد إضافة القطرات لازم أغطي القطرات
+
+213
+00:15:31,600 --> 00:15:36,740
+وأغمر القطرات بـ oil عشان أمنع عملية ال evaporation
+
+214
+00:15:36,740 --> 00:15:41,460
+وأحافظ على الجنين بعد إضافتها فيما بعد طبعا أضيف
+
+215
+00:15:41,460 --> 00:15:45,400
+oil ولا أضيف الجنينات قبل؟ لا بضيف التسع قطرات و
+
+216
+00:15:45,400 --> 00:15:49,240
+بعدين بضيف oil بعد كده تكون جاهزة لإضافة الجنين
+
+217
+00:15:49,240 --> 00:15:53,960
+طبعا فيما بعد بستخدم ال marker علشان أعلم عند
+
+218
+00:15:53,960 --> 00:15:57,180
+الساعة 12 وهي عبارة عن ال position اللي حددناه 
+
+219
+00:15:57,180 --> 00:16:00,920
+من هو دايما بعد في عكس عقارب الساعة انت بتعد في
+
+220
+00:16:00,920 --> 00:16:04,700
+اتجاه عقارب الساعة عكس عقارب الساعة بما يرتقيه
+
+221
+00:16:04,700 --> 00:16:07,760
+يعني في ناس دايما الترقيم يكون عكس عقارب الساعة
+
+222
+00:16:07,760 --> 00:16:11,240
+فبالتالي القطرة التي تكون عند الساعة 12 برقمها 1
+
+223
+00:16:11,240 --> 00:16:16,840
+وببدأ عكس عقارب الساعة ثم بعد ذلك أقوم بإغلاق
+
+224
+00:16:16,840 --> 00:16:21,660
+الطبق يكون كده جاهز لعملية تحميل الجنينات فيه أضعه
+
+225
+00:16:21,660 --> 00:16:25,600
+في الـ incubator على درجة حرارة 37 درجة مئوية لكي
+
+226
+00:16:25,600 --> 00:16:30,120
+تتأقلم مع الـ atmosphere المتعلق بالـ Incubator
+
+227
+00:16:30,120 --> 00:16:36,260
+طبعا هذا شكل الـ Petri dish في الغالب هذا شكل ال
+
+228
+00:16:36,260 --> 00:16:39,820
+Petri dish طبعا هذه في الغالب هي عبارة عن 
+
+229
+00:16:39,820 --> 00:16:43,960
+injection needle وهذه الـ holding pipette هذه
+
+230
+00:16:43,960 --> 00:16:48,140
+القطرة الموجودة في المنتصف هي حوالي 8 قطرات 1 2 3
+
+231
+00:16:48,140 --> 00:16:54,150
+4 5 6 7 8 أي شكل تاني من الأشكال المستخدمة هي
+
+232
+00:16:54,150 --> 00:16:56,770
+القطرة الموجودة في المنتصف هذه التي بعلّم عليها
+
+233
+00:16:56,770 --> 00:17:01,670
+أنا هنا وحواليها الـ line الأحمر هعمل hold .. هعمل
+
+234
+00:17:01,670 --> 00:17:08,190
+عملية loading لـ spermatozoa وبويضاتها و الثمانية
+
+235
+00:17:08,190 --> 00:17:11,770
+المنتصف هعمل عملية loading لـ oocyte للـ  oocyte
+
+236
+00:17:11,770 --> 00:17:15,170
+بعد عملية الـ denudation .. بعد عملية الـ denudation
+
+237
+00:17:15,170 --> 00:17:20,250
+دلوقتي نشوف كيف بتم تحضير الطبق بالطريقة التي
+
+238
+00:17:20,250 --> 00:17:21,970
+تكلمنا فيها قبل بشوية 
+
+239
+00:17:25,390 --> 00:17:28,050
+طبعاً هنا هي الطبق بالـ dropper, sterile dropper
+
+240
+00:17:28,050 --> 00:17:32,490
+بضيف القطرات المطلوبة في بعضهم بضيفها على شكل line
+
+241
+00:17:32,490 --> 00:17:37,110
+في بعضهم بضيفها على شكل دائرة كلاهما صح أنت شو
+
+242
+00:17:37,110 --> 00:17:41,290
+بترتأي وشو بتُرتاح تشتغل ولكن الصح انك تضيفهم على
+
+243
+00:17:41,290 --> 00:17:46,530
+شكل دائرة بعدين ضاف حوالهم الـ oil طبعاً هنا ضاف
+
+244
+00:17:46,530 --> 00:17:50,910
+أربع قطرات وغطاهم بالـ oil والـ oil لازم يغطي 
+
+245
+00:17:50,910 --> 00:17:56,200
+الطبق ككل عشان شو؟ عشان أمنع عملية ال evaporation
+
+246
+00:17:56,200 --> 00:18:01,380
+جهز الطبق لتحميل عليها الجاميطات ولما أقول جاميط
+
+247
+00:18:01,380 --> 00:18:05,600
+يعني male جاميط وfemale جاميط لازم أحمل الـ male وال
+
+248
+00:18:05,600 --> 00:18:10,560
+female بعد مباشرة immediately before injection
+
+249
+00:18:10,560 --> 00:18:14,300
+and under stereomicroscope the centered drop
+
+250
+00:18:14,300 --> 00:18:17,980
+should be removed and replaced with one microliter
+
+251
+00:18:17,980 --> 00:18:25,450
+of sperm suspended diluted in 4µL of 7% PVB ما أعرفش 
+
+252
+00:18:25,450 --> 00:18:28,170
+يعني PVB شو معنى الكلام هذا ببساطة جدا بيقول
+
+253
+00:18:28,170 --> 00:18:32,030
+القطرة التي وضعتها في المنتصف وهي رقم 9 بتزيلها
+
+254
+00:18:32,030 --> 00:18:39,930
+أو تستبدلها بـ 1µL من الـ spermatozoa التي تم
+
+255
+00:18:39,930 --> 00:18:45,890
+تخفيفها في 4µL من الـ PVB يعني كأنه بيقولك ببساطة
+
+256
+00:18:45,890 --> 00:18:51,060
+جدا بتجيب 1µL من الـ spermatozoa التي حضرتها عن طريق
+
+257
+00:18:51,060 --> 00:18:56,300
+الـ Gradient أو حضرتها عن طريق Swim Up وبتعملها
+
+258
+00:18:56,300 --> 00:19:01,820
+Mixing في 4 ملي لتر من ميديا تركيزها 7% تسمى PVP
+
+259
+00:19:01,820 --> 00:19:06,020
+الـ Total Volume 5 تأخذ الخمسة micro وتضيفها مكان
+
+260
+00:19:06,020 --> 00:19:09,680
+القطرة الموجودة في المنتصف مش كده في البداية قلت
+
+261
+00:19:09,680 --> 00:19:12,240
+القطرة التاسعة الموجودة في المنتصف هي القطرة التي
+
+262
+00:19:12,240 --> 00:19:14,760
+يحمل عليها spermatozoa
+
+263
+00:19:17,710 --> 00:19:20,650
+باستخدام الـ Pasteur Pipette أو Plastic Pipette بتكون 
+
+264
+00:19:20,650 --> 00:19:24,010
+ضمن ديامتر معين باجي بنقل البويضات التي عملتي لها
+
+265
+00:19:24,010 --> 00:19:28,110
+denudation وبضع في كل قطرة الموجودة على الجوانب 
+
+266
+00:19:28,110 --> 00:19:32,590
+بويضة أو بويضتين بناء على عدد البويضات التي موجودة 
+
+267
+00:19:32,590 --> 00:19:37,130
+عندي لأن هتصير أتحرك من المنتصف من القطرة التي
+
+268
+00:19:37,130 --> 00:19:40,310
+تحتوي على الـ spermatozoa إلى القطرة التي تحتوي
+
+269
+00:19:40,310 --> 00:19:44,510
+على الـ oocyte فمن المنتصف للخارج من المنتصف للخارج 
+
+270
+00:19:44,510 --> 00:19:50,170
+عشان كده مهم جدا أحدد الساعة 12 وين هي طالما أحدد
+
+271
+00:19:50,170 --> 00:19:54,930
+الساعة 12 هي نقطة البداية نقطة البداية So what is
+
+272
+00:19:54,930 --> 00:20:00,430
+the function of PVB media during ICSI? The PVB
+
+273
+00:20:00,430 --> 00:20:03,710
+media has four function or three function The
+
+274
+00:20:03,710 --> 00:20:07,970
+first function reduce the motility of spermatozoa
+
+275
+00:20:08,430 --> 00:20:11,410
+احنا بنعرف إنه sperm very fast فأنا بعمل عشان
+
+276
+00:20:11,410 --> 00:20:14,990
+أعمله catching بدي أعمله reducing للموتility عشان 
+
+277
+00:20:14,990 --> 00:20:19,990
+أتحرك ببطء وأقدر أعمله catching و pick up ثاني بدي
+
+278
+00:20:19,990 --> 00:20:23,030
+أعمل ال preventing لل sticking في ال inner surface
+
+279
+00:20:23,030 --> 00:20:27,090
+من الـ injection tube أنا لما أجي أمسك ال sperm
+
+280
+00:20:27,090 --> 00:20:30,430
+وأعمله suction ممكن ال sperm يلتصق بالجدار 
+
+281
+00:20:30,430 --> 00:20:34,290
+الداخلي للـ needle فأنا بدي أمنع هذه العملية من
+
+282
+00:20:34,290 --> 00:20:40,140
+خلال استخدام الـ BVP فبتعمل زي غشاء لاصق يمنع التصاق
+
+283
+00:20:40,140 --> 00:20:44,200
+للـ sperm بالـ inner surface of injection needle
+
+284
+00:20:44,200 --> 00:20:47,840
+to give more control over the flow of fluid in the
+
+285
+00:20:47,840 --> 00:20:54,120
+exit أيضًا بسمح لي أن أتحكم بدخول وخروج الـ sperm
+
+286
+00:20:54,120 --> 00:20:58,260
+بكل سهولة لأن الفسكوسية التي تبعت الـ BVP media إلى
+
+287
+00:20:58,260 --> 00:21:04,450
+حد عالية فبتتحرك بدرجة خفيفة من السرعة ما بتتحرك 
+
+288
+00:21:04,450 --> 00:21:07,430
+بسرعة فبالتالي بفقد الـ sperm بسرعة فبالتالي هذه
+
+289
+00:21:07,430 --> 00:21:13,410
+اللزوجة مهمة جدا في التحكم في عملية تدفق السائل أو
+
+290
+00:21:13,410 --> 00:21:18,930
+تدفق وحركة الـ sperm الـ media which is usually
+
+291
+00:21:18,930 --> 00:21:21,870
+present in the cultural media has the ability to
+
+292
+00:21:21,870 --> 00:21:25,250
+act as membrane and egg شو يعني membrane بعد egg
+
+293
+00:21:25,250 --> 00:21:30,190
+بقول الـ media اللي أنا استخدمتها واللي خلطت فيها
+
+294
+00:21:30,190 --> 00:21:34,150
+واحد microliter من الـ sperm تستخدم كلاسق زي
+
+295
+00:21:34,150 --> 00:21:38,590
+plaster شو دخل الـ plaster في الموضوع؟ في مصطلح
+
+296
+00:21:38,590 --> 00:21:43,210
+هناخده كمان شوية اسمه spermatozoa immobilization
+
+297
+00:21:43,210 --> 00:21:48,590
+يعني إعطاب الحيوان المنوي أو إفقاد قدرة الحركة لدى
+
+298
+00:21:48,590 --> 00:21:51,690
+الحيوان المنوي كيف بتصير هذه؟ من خلال جرح الحيوان
+
+299
+00:21:51,690 --> 00:21:58,090
+المنوي أو قطع جزء من ذيل الخاص بحيوان المنوي لو أنا
+
+300
+00:21:58,580 --> 00:22:02,080
+عملت sharpening cutting في الـ tail of الـ
+
+301
+00:22:02,080 --> 00:22:05,820
+spermatozoa كل المادة الموجودة في الـ sperm هتتدفق
+
+302
+00:22:05,820 --> 00:22:10,760
+في الخارج ولكن وجود الـ BVP media بتعمل زي plaster
+
+303
+00:22:10,760 --> 00:22:15,200
+فبتمنع عملية التدفق وإلا أنا هفقد كل المواد
+
+304
+00:22:15,200 --> 00:22:18,980
+اللازمة لإتمام عملية الـ fertilization وبكدا أنا
+
+305
+00:22:18,980 --> 00:22:23,340
+فقدت الـ sperm عشان كده بقولك أن الـ BVP media بتعمل
+
+306
+00:22:23,340 --> 00:22:28,870
+زي الـ membrane or band aid يعني اللاصقة الخاصة
+
+307
+00:22:28,870 --> 00:22:32,230
+بالإسعافات الأولية الـ Plasma Brain Damage induced
+
+308
+00:22:32,230 --> 00:22:36,650
+by the touching tail does not allow anything from
+
+309
+00:22:36,650 --> 00:22:39,610
+the sperm cell to leak into the surrounding media
+
+310
+00:22:39,610 --> 00:22:45,170
+أيضًا، الـ sperm cell بعد عملية الـ immobilization،
+
+311
+00:22:45,170 --> 00:22:48,710
+بجد الـ immobilization عفوًا، بجد أن الـ sperm لا
+
+312
+00:22:48,710 --> 00:22:54,070
+يزال يبقى قادر على إخصاب البويضة لفترة زمنية
+
+313
+00:22:54,070 --> 00:23:00,970
+تتراوح لعدد ساعات مش many hours .. several hours
+
+314
+00:23:00,970 --> 00:23:07,250
+هذا بعد الـ gamete immobilization طيب حملت الحيوانات
+
+315
+00:23:07,250 --> 00:23:10,890
+المنوية في القطارة الموجودة في المنتصف حالياً هالشيء
+
+316
+00:23:10,890 --> 00:23:14,090
+على نقطة تانية أن بتعمل catching للحيوان المنوي
+
+317
+00:23:14,090 --> 00:23:17,770
+لأن مش كل sperm أنا بدي أستخدمها بدي أستخدم
+
+318
+00:23:17,770 --> 00:23:21,430
+الحيوان المنوي الـ morphological normal و بتحرك
+
+319
+00:23:21,430 --> 00:23:25,950
+بشكل طبيعي في مصطلح بنسميه catching the sperm كيف
+
+320
+00:23:25,950 --> 00:23:30,850
+بتعمل catching للـ sperm؟ و أنا جئت بعمل
+
+321
+00:23:30,850 --> 00:23:34,110
+denudation و خلصت؟ بتعمل catching of spermatozoa
+
+322
+00:23:34,110 --> 00:23:39,150
+من خلال أني أسحب ثلاثة أربعة sperm و أعملهم
+
+323
+00:23:39,150 --> 00:23:43,850
+immobilization شو يعني immobilization؟ يعني إعطاب
+
+324
+00:23:43,850 --> 00:23:49,470
+و فقدان الحركة من خلال جرح الـ sperm Since in most
+
+325
+00:23:49,470 --> 00:23:52,610
+of patients specific percentage of sperm is
+
+326
+00:23:52,610 --> 00:23:55,950
+motile, embryologists are faced with the problem
+
+327
+00:23:55,950 --> 00:24:00,450
+of catching this gamete before to immobilization
+
+328
+00:24:00,450 --> 00:24:03,570
+and injection يعني أول مشكلة بتواجهني ك
+
+329
+00:24:03,570 --> 00:24:09,130
+embryologist كيف أستطيع أن أمسك هذا الجاميت أو هذه
+
+330
+00:24:09,130 --> 00:24:13,530
+الجامتات الذكرية ليه المشكلة؟ لأن الحيوان حكيت أنه
+
+331
+00:24:13,530 --> 00:24:17,640
+بيتحرك بسرعة فما بقدر أتحكم فيه فبدّي شيء يعمل
+
+332
+00:24:17,640 --> 00:24:21,880
+reduction لـ motility و inhibition وهي الـ BVP
+
+333
+00:24:21,880 --> 00:24:25,360
+media شو الـ media أو الـ procedure can be performed
+
+334
+00:24:25,360 --> 00:24:31,500
+in the different .. خلّيني أسميها type of media زي
+
+335
+00:24:31,500 --> 00:24:35,340
+الـ culture media in general الـ BVP media وحاجة
+
+336
+00:24:35,340 --> 00:24:38,860
+بتسميها more physiological viscous solution يعني
+
+337
+00:24:38,860 --> 00:24:44,860
+هذه ثلاث أمور مهمة جدا تلقى دور كبير في اختزال حركة
+
+338
+00:24:44,860 --> 00:24:49,550
+الحيواناتثير عملية الـ catching أو الـ pick-up للـ
+
+339
+00:24:49,550 --> 00:24:52,510
+spermatozoa الـ PVP media الـ physiological
+
+340
+00:24:52,510 --> 00:24:57,390
+viscous media و الـ cultured media loading process
+
+341
+00:24:57,390 --> 00:25:01,350
+sperm sample into media drop on the exodash has
+
+342
+00:25:01,350 --> 00:25:04,930
+the benefit that motile sperm will automatically
+
+343
+00:25:04,930 --> 00:25:08,670
+separated from immotile gamete, somatic cell and
+
+344
+00:25:08,670 --> 00:25:13,390
+other debris أنت بمجرد ما تخلط واحد microliter من
+
+345
+00:25:13,390 --> 00:25:17,350
+الـ spermatozoa بعد الـ swim upمع أربعة من PVP
+
+346
+00:25:17,350 --> 00:25:20,610
+تركيزه سبعة وتحميلها في القطرة الموجودة في الـ
+
+347
+00:25:20,610 --> 00:25:24,530
+center هذا سرعان ما يساعد الـ sperm أن يصير
+
+348
+00:25:24,530 --> 00:25:28,950
+separation between normal sperm, live sperm and
+
+349
+00:25:28,950 --> 00:25:32,990
+other type of spermatozoa and the debris هذا يعني
+
+350
+00:25:32,990 --> 00:25:38,910
+خطوة إضافية من ناحية الـ purification this make the
+
+351
+00:25:38,910 --> 00:25:43,010
+purity of whole drop much higher and minimized the
+
+352
+00:25:43,010 --> 00:25:46,850
+contamination theoreticallyيعني هذه الخطوة عملية
+
+353
+00:25:46,850 --> 00:25:53,070
+الـ mixing بتقلل الـ motility وبتقلل أي خطأ ولو
+
+354
+00:25:53,070 --> 00:25:56,430
+كانت خطأ نظري أو contamination بشكل نظري however
+
+355
+00:25:56,430 --> 00:26:00,410
+this mode of catching sperm has the drawback that
+
+356
+00:26:00,410 --> 00:26:03,250
+without viscous solution covering the inner
+
+357
+00:26:03,250 --> 00:26:06,030
+surface of the injection pipet sperm manipulation
+
+358
+00:26:06,030 --> 00:26:11,410
+during injection is not smoothly عدم وجود solution
+
+359
+00:26:11,410 --> 00:26:16,000
+داخل الـ injection needle الفسكوسية تبعته عالية معناها الـ
+
+360
+00:26:16,000 --> 00:26:19,620
+catching للـ sperm مش هتكون سهلة مش هتكون لطيفة مش
+
+361
+00:26:19,620 --> 00:26:24,060
+هتكون بالصورة just game لأ هتتغلر فيها بشكل كبير
+
+362
+00:26:24,060 --> 00:26:29,160
+جدا و أي حركة و لو كانت حركة عبثية أو غير محسوبة
+
+363
+00:26:29,160 --> 00:26:32,740
+هضيع الـ sperm فالمبالك لو أنت بتشتغل على عين مافيش
+
+364
+00:26:32,740 --> 00:26:36,400
+فيها الله أربعة sperm أربعة sperm ماتو زواج this
+
+365
+00:26:36,400 --> 00:26:39,940
+problem cannot be overcome but it can be reduced
+
+366
+00:26:39,940 --> 00:26:47,740
+by washing the XYZ tool by PVPأي العملية هذه عشان
+
+367
+00:26:47,740 --> 00:26:51,520
+أقلل الخطأ اللي فيها و أتحكم بالـ spermatozoa و ال
+
+368
+00:26:51,520 --> 00:26:54,880
+aspiration للـ spermatozoa بشكل كبير جدا و أمنع ال
+
+369
+00:26:54,880 --> 00:26:59,360
+contamination و أتحكم بالـ flow و تدفق السائل
+
+370
+00:26:59,360 --> 00:27:02,940
+خلال عملية الـ injection أو الـ aspiration لازم أغسل
+
+371
+00:27:02,940 --> 00:27:08,000
+الـ media عفوا أغسل الـ tools الخاصة بالـ exit tools
+
+372
+00:27:08,000 --> 00:27:11,380
+زي الـ holder و الـ injection بالـ BVP media كيف
+
+373
+00:27:11,380 --> 00:27:14,780
+أغسلهم؟ بعمل aspiration و releasing sucking و
+
+374
+00:27:14,780 --> 00:27:19,280
+releasing كإن أنا بخسلها من الداخل it is
+
+375
+00:27:19,280 --> 00:27:22,660
+recommended that minimum volume of media is placed
+
+376
+00:27:22,660 --> 00:27:26,740
+in the exit pipet and that sperm is placed in the
+
+377
+00:27:26,740 --> 00:27:30,040
+foremost third of visible part of a glass tool بعد
+
+378
+00:27:30,040 --> 00:27:32,360
+أن أنت ما تعمل aspiration و releasing suction و
+
+379
+00:27:32,360 --> 00:27:36,540
+releasing للـ PVP media داخل الـ injection needle و ال
+
+380
+00:27:36,540 --> 00:27:40,040
+holder pipet بعد كده تبقى الـ catching للـ sperm
+
+381
+00:27:40,040 --> 00:27:44,960
+بسهولة و خدوا بالكم الـ catching للـ sperm لازم أنا
+
+382
+00:27:44,960 --> 00:27:47,680
+بعد ما أعمل catching و أدخل الـ sperm داخل ال
+
+383
+00:27:47,680 --> 00:27:51,200
+needle لازم يظهر الـ sperm تحت النظر كافي يظهر تحت
+
+384
+00:27:51,200 --> 00:27:54,780
+النظر نص الـ needle بتكون ظاهرة في الـ microscope
+
+385
+00:27:54,780 --> 00:27:59,500
+فلازم يكون الـ sperm في الثلث الأول من الـ needle
+
+386
+00:27:59,500 --> 00:28:03,740
+عشان أتأكد أن الـ sperm موجود في الـ needle بعد كده
+
+387
+00:28:03,740 --> 00:28:07,800
+الـ embryologist في عنده مشكلة هل يسحب الـ sperm من
+
+388
+00:28:07,800 --> 00:28:11,510
+الـ head؟ ولا يسحب الـ sperm من الـ tail لما أنا ببدأ
+
+389
+00:28:11,510 --> 00:28:15,710
+أسحب الـ sperm لأول مرة عشان أحوله لخطوة ال
+
+390
+00:28:15,710 --> 00:28:20,030
+immobilization بسحبه من الـ head لأنه أسهل تصور أن
+
+391
+00:28:20,030 --> 00:28:23,870
+عندك sperm الـ head كبير واضح و الـ tail متحرك تمسكه
+
+392
+00:28:23,870 --> 00:28:26,410
+من الـ tail ولا تمسكه من الـ head لأ أنا بعمله
+
+393
+00:28:26,410 --> 00:28:30,110
+suction من الـ head لأنه أسهل بعد ما أعمله
+
+394
+00:28:30,110 --> 00:28:33,330
+immobilization بعمله suction من الـ tail لأن ال
+
+395
+00:28:33,330 --> 00:28:39,280
+tail فقد قدرته على الحركة في مشكلة تانية بتواجهني
+
+396
+00:28:39,280 --> 00:28:45,600
+أن لما أجي أعمل injection بلاقي أن جزء من الـ PVP
+
+397
+00:28:45,600 --> 00:28:48,700
+media الموجود داخل الـ injection needle قد يدخل إلى
+
+398
+00:28:48,700 --> 00:28:52,920
+الـ cytoplasm للـ oocyte وإذا أنت ما كنتش صاحي
+
+399
+00:28:52,920 --> 00:28:57,160
+للموضوع ده كمية كبيرة جدا تدخل للـ oocyte cytoplasm
+
+400
+00:28:57,160 --> 00:29:01,800
+فده بيعمل مشاكل خلال عملية تطور الـ oocyte الملقحة
+
+401
+00:29:01,800 --> 00:29:06,650
+وانقسامها طب ليه بيعمل مشاكل؟ لأن المجلد densityو الـ
+
+402
+00:29:06,650 --> 00:29:11,430
+size تبع جزيئات الـ PVP Media كبيرة إلى حد ما فما
+
+403
+00:29:11,430 --> 00:29:15,110
+تستطيع الـ oocyte تتخلص منها من خلال القنوات
+
+404
+00:29:15,110 --> 00:29:18,470
+الموجودة في الـ plasma membrane الخاصة بالـ oocyte
+
+405
+00:29:18,470 --> 00:29:23,350
+عشان كده لازم تكون حذر و ما تتنزل كمية كبيرة جدا
+
+406
+00:29:23,350 --> 00:29:27,910
+أو تدخل كمية كمية كبيرة جدا من الـ PVP Media داخل
+
+407
+00:29:27,910 --> 00:29:31,690
+الـ oocyte إلا بالحد القليل المسموح طب كيف ده
+
+408
+00:29:31,690 --> 00:29:37,660
+بتصير؟ ببساطة جدا لما انتيجت تخترق قبل ما تخترق
+
+409
+00:29:37,660 --> 00:29:43,160
+البويضة هتنزل الـ sperm إلى أقرب نقطة من فوهة ال
+
+410
+00:29:43,160 --> 00:29:47,920
+injection needle وبعدين تخترق البويضة هتسحب جزء
+
+411
+00:29:47,920 --> 00:29:51,680
+بسيط من الـ cytoplasm عشان تتأكد أنك داخل الـ oocyte
+
+412
+00:29:51,680 --> 00:29:56,180
+مش خرقت من أو تم اختراق الـ oocyte من جانب وخرجت
+
+413
+00:29:56,180 --> 00:30:01,040
+من الجانب الآخر إذا سحبت الـ cytoplasm وتأكدت أن ال
+
+414
+00:30:01,040 --> 00:30:04,500
+cytoplasm سحب قدامك وتشافت تحت الـ microscope معناه
+
+415
+00:30:04,500 --> 00:30:09,600
+أنت داخل الـ Oocyte هتعمل releasing للـ sperm أول
+
+416
+00:30:09,600 --> 00:30:13,640
+ما الـ sperm ينزل من الـ injection needle هترفع
+
+417
+00:30:13,640 --> 00:30:19,720
+وتعمل عملية removing للـ injection needle من الـ
+
+418
+00:30:19,720 --> 00:30:24,500
+cytoplasm فبالتالي بتكون كميات ضئيلة جدا من الـ BVP
+
+419
+00:30:24,500 --> 00:30:28,800
+media الموجودة بداخل الـ injection needle وفرغت
+
+420
+00:30:28,800 --> 00:30:32,100
+داخل الـ oocyte فبالتالي تأثيرها بيكون إلى حد ما
+
+421
+00:30:32,100 --> 00:30:38,850
+محدود أو معدوم طيب كيف أنا أبدأ أعمل عملية ال
+
+422
+00:30:38,850 --> 00:30:41,950
+catching؟ في عندي طريقتين الطريقة الأولى بيسموها
+
+423
+00:30:41,950 --> 00:30:45,390
+sperm slow  والطريقة الثانية بيسموها sperm 
+
+424
+00:30:45,390 --> 00:30:50,550
+catching طبعا كلاهما أو كلا الطريقتين باعتمدوا على
+
+425
+00:30:50,550 --> 00:30:55,830
+مبدأ واحد وهو عبارة عن ما يليه the major compound
+
+426
+00:30:55,830 --> 00:31:01,740
+of the cumulus cell matrix هي هيالورونات slow down to
+
+427
+00:31:01,740 --> 00:31:05,160
+move the spermatozoa and could act as natural
+
+428
+00:31:05,160 --> 00:31:10,540
+alternative to PVP وجدوا أن الـ Oocyte خلاياها
+
+429
+00:31:10,540 --> 00:31:14,740
+تحتوي على كمية كبيرة جدا cumulus cell matrix تحتوي
+
+430
+00:31:14,740 --> 00:31:18,920
+على مركب طبيعي يسمى هيالورونات وهذا اللي هي
+
+431
+00:31:18,920 --> 00:31:24,340
+هيالورونات يلعب دور كبير جدا في إنقاص وخفض واختزال
+
+432
+00:31:24,340 --> 00:31:29,980
+الحركة لدى ال spermatozoa فبالتالي أستطيع استخدام
+
+433
+00:31:30,660 --> 00:31:35,220
+دم هذا المركب الطبيعي بدلاً من الـ PVP media
+
+434
+00:31:35,220 --> 00:31:40,100
+اللي هي هيالورونات relatively high negative charge
+
+435
+00:31:40,100 --> 00:31:44,680
+and high hydration capacity which allow for the
+
+436
+00:31:44,680 --> 00:31:47,500
+preparation of solution with adequate viscosity
+
+437
+00:31:47,500 --> 00:31:52,940
+for exit ليه السبب أو شو السبب اللي خلى اللي هي
+
+438
+00:31:52,940 --> 00:31:59,140
+هيالورونات مقابل أو عوض عن ال PVP أو alternative لل
+
+439
+00:31:59,140 --> 00:32:03,820
+PVP عدة أسباب منه الـ Negative Charge منه أن الـ
+
+440
+00:32:03,820 --> 00:32:08,140
+Hydration  كبسية عالية جدا كلاهما يمنحان القدرة
+
+441
+00:32:08,140 --> 00:32:14,080
+بالتكوين محلول لزوجته عالية أو كافية لإعاقة
+
+442
+00:32:14,080 --> 00:32:17,800
+حركة الـ spermatozoa والتحكم بشكل كبير في عملية
+
+443
+00:32:17,800 --> 00:32:21,940
+التلقيح It has been reported that its effect on
+
+444
+00:32:21,940 --> 00:32:26,020
+the sperm motility is reversible يعني تأثير
+
+445
+00:32:26,020 --> 00:32:28,840
+الهيالورونات إضافة إلى ذلك تأثيره على ال spermatozoa
+
+446
+00:32:28,840 --> 00:32:33,420
+غير دائم reversible مش irreversible لا reversible
+
+447
+00:32:33,420 --> 00:32:41,560
+يعني عكسي and is used and it is used and it is
+
+448
+00:32:41,560 --> 00:32:44,260
+used does not affect the outcome of treatment
+
+449
+00:32:44,260 --> 00:32:47,380
+cycle in term fertilization pregnancy and live
+
+450
+00:32:47,380 --> 00:32:51,280
+birth rate بمعنى آخر رغم أنه تأثيره على ال sperm
+
+451
+00:32:51,280 --> 00:32:55,440
+motility تأثير ليس بدائم أيضا الدراسات قالت ما
+
+452
+00:32:55,440 --> 00:32:58,000
+بتأثر على ال pregnancy rate ما بتأثر على ال
+
+453
+00:32:58,000 --> 00:33:01,460
+fertilization rate ما بتأثر على معدل الحصول على
+
+454
+00:33:01,460 --> 00:33:06,920
+live births وهذا شيء مهم جدا خلال عملية الإخصاب وال
+
+455
+00:33:06,920 --> 00:33:11,660
+injection سنكتفي بهذا القدر في هذه المحاضرة على أن 
+
+456
+00:33:11,660 --> 00:33:16,780
+نلتقي في محاضرة جديدة إن شاء الله دمتم في حفظ
+
+457
+00:33:16,780 --> 00:33:19,140
+الله والسلام عليكم ورحمة الله
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/1ufMvFV5K5U_postprocess.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/1ufMvFV5K5U_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..2ecd61d90c736026c31351b5fb58cf50c3840334
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/1ufMvFV5K5U_postprocess.srt
@@ -0,0 +1,1828 @@
+1
+00:00:00,890 --> 00:00:05,230
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,230 --> 00:00:11,250
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا
+
+3
+00:00:11,250 --> 00:00:16,490
+الأعزاء أرجو من الله الكريم أن تكونوا جميعا بخير و
+
+4
+00:00:16,490 --> 00:00:22,890
+بصحة جيدة اليوم سوف ننتقل إلى موضوع جديد يكمل ما
+
+5
+00:00:22,890 --> 00:00:28,870
+سبقه من مواضيع خاصة لمساق التلقيح الصناعي طرقه
+
+6
+00:00:28,870 --> 00:00:34,620
+وأساليبهالموضوع اليوم يتحدث عن الـ IGESI وهو عبارة
+
+7
+00:00:34,620 --> 00:00:40,660
+عن اختصار لكلمة يُقصد بها Intracytoplasmic sperm
+
+8
+00:00:40,660 --> 00:00:46,140
+injection يعني الحقن المجهري باستخدام حيوان منوي
+
+9
+00:00:46,140 --> 00:00:51,060
+واحد سنتكلم في هذا ال chapter عن عدة أمور منها
+
+10
+00:00:51,060 --> 00:00:56,020
+القالية المستخدمة في القبض على الحيوان المنوي تحت
+
+11
+00:00:56,020 --> 00:00:59,600
+مصطلحSpermatozoa Catching or Catching of
+
+12
+00:00:59,600 --> 00:01:04,300
+Spermatozoa مصطلح إعطاب الحيوان المنوي وفقدان
+
+13
+00:01:04,300 --> 00:01:08,360
+القدرة على الحركة من خلال مصطلح بنسميه sperm
+
+14
+00:01:08,360 --> 00:01:12,860
+immobilization بعدين ننتقل إلى الميكروسكوب الذي
+
+15
+00:01:12,860 --> 00:01:17,360
+يستخدم في الحقن المجهري ننتقل للتحدث عن ال media
+
+16
+00:01:17,360 --> 00:01:21,980
+التي تقلل من حركة الحيوان المنوي ننتقل إلى آلية
+
+17
+00:01:21,980 --> 00:01:27,100
+الحقنثم نتدرج فيما بعد إلى تطور الجنين منذ لحظة
+
+18
+00:01:27,100 --> 00:01:32,660
+حقن الحيوان المنوي حتى لحظة الإرجاع داخل رحمه سيدة
+
+19
+00:01:32,660 --> 00:01:38,540
+بداية عندما نقول IGESI هي عبارة عن تلمة مكوّنة من
+
+20
+00:01:38,540 --> 00:01:45,160
+أربع حروف الحرف الأول I-C-S-I وهي اختصار
+
+21
+00:01:45,160 --> 00:01:49,820
+للـIntracytoplasmic sperm injection يعني حقن
+
+22
+00:01:49,820 --> 00:01:56,490
+الحيوان داخل الـcytoplasmوهذه العملية تشمل اختيار
+
+23
+00:01:56,490 --> 00:02:01,170
+single sperm وعمل insertion لهذا ال sperm داخل ال
+
+24
+00:02:01,170 --> 00:02:06,050
+oocyte بشرط أن تكون هذه الخيلية أو هذه البويضة
+
+25
+00:02:06,050 --> 00:02:11,930
+ناضجة أي هي عبارة عن بويضة استقرت في ال metaphase
+
+26
+00:02:11,930 --> 00:02:17,010
+الخاص بالانقسام الميوزي الثاني By passing all the
+
+27
+00:02:17,010 --> 00:02:21,630
+egg coat penetration and jameed fusion step
+
+28
+00:02:22,000 --> 00:02:26,460
+characterized of natural fertilization من خلال
+
+29
+00:02:26,460 --> 00:02:30,200
+اختراق جميع الأغلفة المحيطة بالبوايضة ووصول إلى
+
+30
+00:02:30,200 --> 00:02:33,300
+الـcytoplasm يتم إطلاق الحيوان المنوي في
+
+31
+00:02:33,300 --> 00:02:36,960
+الـcytoplasm الخاص بالبوايضة مما يسمح باندماج
+
+32
+00:02:36,960 --> 00:02:41,020
+النواة الذكرية مع النواة الأنثوية لتكوين خلية
+
+33
+00:02:41,020 --> 00:02:45,500
+جديدة هذه العملية بالمجمل تسمى الإخصاب أو ال
+
+34
+00:02:45,500 --> 00:02:49,540
+fertilization أول ما تم إنشاء ال XE كان على ال
+
+35
+00:02:49,540 --> 00:02:54,260
+rabbit بشكل أساسيوأول عملية تم فيها استخدام ل
+
+36
+00:02:54,260 --> 00:02:58,040
+human جميد كانت وادت طبعا إلى حدوث ال pregnancy
+
+37
+00:02:58,040 --> 00:03:03,900
+كانت حوالي فيها بداية عام 1992 ثم بعد ذلك توالت
+
+38
+00:03:03,900 --> 00:03:09,180
+الحالات وتوالى إنجاب أطفال باستخدام خاصية الحقن
+
+39
+00:03:09,180 --> 00:03:15,740
+المجهري أو تقنية الحقن المجهري اللي اسمها EXIT the
+
+40
+00:03:15,740 --> 00:03:18,700
+technique was developed to help achieve the
+
+41
+00:03:18,700 --> 00:03:22,840
+fertilizationfor couples لمين ال couples؟ أو هل
+
+42
+00:03:22,840 --> 00:03:26,340
+التقنية تساعد مين؟ تساعد ال couples اللي عندهم
+
+43
+00:03:26,340 --> 00:03:31,380
+مشكلة في ال infertility وبكون سبب هذه المشكلة male
+
+44
+00:03:31,380 --> 00:03:35,580
+بشكل أساسي أو ال couples اللي عندهم مشكلة في
+
+45
+00:03:35,580 --> 00:03:40,860
+الحصول على بويضة ملقحة أو تلقيح البويضة بشكلها
+
+46
+00:03:40,860 --> 00:03:45,460
+الطبيعي وهي عبارة عن الحاجة بتسميها in vivo
+
+47
+00:03:45,460 --> 00:03:48,940
+fertilization يعني عند two couples عندهم مشكلة في
+
+48
+00:03:48,940 --> 00:03:53,170
+التلقيح الطبيعيأو two couples مشكلتهم خاصة بالميل
+
+49
+00:03:53,170 --> 00:03:58,490
+وهذه المشكلة بتكون في مراحل متقدمة بشكل كبير جدا
+
+50
+00:03:58,490 --> 00:04:05,090
+طبعا متى نلجأ إلى الإجزي؟ بشكل عام إذا كان عندي ما
+
+51
+00:04:05,090 --> 00:04:09,550
+يقارب من حيث الcement parameter عدد ال sperm أو ال
+
+52
+00:04:09,550 --> 00:04:13,210
+concentration of sperm ماتزوّع في الcement fluid
+
+53
+00:04:13,210 --> 00:04:18,910
+أقل من 5 مليون sperm per milliliter ساعتهاهذه
+
+54
+00:04:18,910 --> 00:04:24,710
+الحالة يمكن أن تُستخدم إلى الـ EXY أو الـ IVF ولكن
+
+55
+00:04:24,710 --> 00:04:29,530
+بشكل عام كل ما قل عدد ال sperm كل ما قل عدد ال
+
+56
+00:04:29,530 --> 00:04:34,530
+sperm المتحركنميل إلى استخدام الإجزي أفضل من ال
+
+57
+00:04:34,530 --> 00:04:38,490
+IVF So, likelihood of fertilization with a
+
+58
+00:04:38,490 --> 00:04:41,990
+standard IVF is significantly reduced and
+
+59
+00:04:41,990 --> 00:04:45,030
+therefore such couples should be considered
+
+60
+00:04:45,030 --> 00:04:49,090
+unstable for this procedure particularly where
+
+61
+00:04:49,090 --> 00:04:53,590
+less than 1% normal form while we are observed
+
+62
+00:04:53,590 --> 00:04:57,370
+يعني إذا كان عندى عدد الحيوانات المنوية الموجودة
+
+63
+00:04:57,370 --> 00:05:02,550
+في العين أقل من 5 مليون يميل إلى ال IVFكل ما قل ..
+
+64
+00:05:02,550 --> 00:05:06,250
+كل ما قل عدد الحيوانات المنوية كل ما قل عدد
+
+65
+00:05:06,250 --> 00:05:10,890
+الحيوان منوي المتحرك نلجأ إلى ال exit فبالتالي
+
+66
+00:05:10,890 --> 00:05:15,730
+بشكل مجمل إذا كان عندك كمية ال motile كمية قليلة
+
+67
+00:05:15,730 --> 00:05:20,870
+جدا جدا تكاد تعاد على أصابع يد الواحدة أو تعاد
+
+68
+00:05:20,870 --> 00:05:24,550
+بشكل مئات فقط لا غير ولا تصل إلى آلاف أو مئات
+
+69
+00:05:24,550 --> 00:05:28,720
+الألاف ساعتها هذه ال couplesوهذه ال case تروح إلى
+
+70
+00:05:28,720 --> 00:05:34,020
+الحقن المجهري و لا تذهب إلى التلقيح الصناعي المسمى
+
+71
+00:05:34,020 --> 00:05:38,420
+بال IVF however, fertilization of mature oocyte
+
+72
+00:05:38,420 --> 00:05:42,760
+may still fail to occur in the presence of normal
+
+73
+00:05:42,760 --> 00:05:47,520
+sperm because of hardening or very hard
+
+74
+00:05:47,520 --> 00:05:51,880
+xenopelicida or when oocyte revival or plasma
+
+75
+00:05:51,880 --> 00:05:57,110
+inclusion بعض الأحيان بيكون عنديالـ Cytoplasm
+
+76
+00:05:57,110 --> 00:06:01,110
+بيكون عنده عدد الحيوانات المنوية طبيعي بشكل أو
+
+77
+00:06:01,110 --> 00:06:06,950
+باخر ولكن تفشل عملية التلقيح بسبب ما يلي السبب
+
+78
+00:06:06,950 --> 00:06:09,470
+الأول أن يكون فيها اندزونة بليوسيدا very hard
+
+79
+00:06:09,470 --> 00:06:13,430
+فيصعب على ال sperm أن يخترقها بطريقة التلقيح
+
+80
+00:06:13,430 --> 00:06:17,290
+الطبيعي أو طريقة التلقيح في المختبر ما يعرف باسم
+
+81
+00:06:17,290 --> 00:06:21,330
+ال IVF بخلاف ال exitالـ IVF أنا بخلّي الجميط مع
+
+82
+00:06:21,330 --> 00:06:25,010
+بعض وبعض الـ oocyte مع ال sperm وبتيح الفرصة لل
+
+83
+00:06:25,010 --> 00:06:29,270
+sperm أن يخترق البوادة بس في ال XE أنا اللي بخترق
+
+84
+00:06:29,270 --> 00:06:32,950
+البوادة و بدخل ال sperm من خلال ال needle في بعض
+
+85
+00:06:32,950 --> 00:06:36,430
+الأحيان بيكون عندي ال normal semen parameter
+
+86
+00:06:36,430 --> 00:06:39,780
+normal أو ال semen parameter as normalباراميترا
+
+87
+00:06:39,780 --> 00:06:44,920
+ولكن يفشل ال sperm في عملية التلقيح بسبب زيادة في
+
+88
+00:06:44,920 --> 00:06:49,960
+صعوبة اختراق البوايدة او فقدار ال sperm القدرة في
+
+89
+00:06:49,960 --> 00:06:54,700
+اختراق البوايدة بسبب زيادة ال thickness تبعة
+
+90
+00:06:54,700 --> 00:06:58,280
+الزونا بليوسيدا أو الصلابةالشغل التاني أن يكون
+
+91
+00:06:58,280 --> 00:07:01,920
+الـcytoplasm of oocyte يحتوى على بعض الـinclusion
+
+92
+00:07:01,920 --> 00:07:05,820
+body التي تعيق الـSpermatozoa من عملية الاختراق
+
+93
+00:07:05,820 --> 00:07:08,940
+لأبنرمالات الفيزيوناب اليوسيدا أكيد بتعمل
+
+94
+00:07:08,940 --> 00:07:11,700
+الـpreventation وpreventing للـSperm fusion
+
+95
+00:07:11,700 --> 00:07:17,280
+فبالتالي يصعب عملية الاختراق أيضًا منها الـSperm
+
+96
+00:07:17,280 --> 00:07:21,040
+may not move in normal fusion الـSperm ما بتتحرك
+
+97
+00:07:21,040 --> 00:07:24,630
+بالشكل الطبيعي فبالتالي ما بيخترق بالشكل الطبيعيأو
+
+98
+00:07:24,630 --> 00:07:27,810
+الـ sperm عنده troubleshooting في عملية الـ
+
+99
+00:07:27,810 --> 00:07:31,110
+attached مع الـ receptor الموجودة على ال egg
+
+100
+00:07:31,110 --> 00:07:36,290
+فبالتالي هذه الأمور الصلابة في الزوناب اليسدة وجود
+
+101
+00:07:36,290 --> 00:07:39,430
+inclusion body في الـ cytoplasm الخاص بالـ oocyte
+
+102
+00:07:39,430 --> 00:07:43,870
+وجود خطأ في حركة الحيوان المنوي أو حركة الحيوان
+
+103
+00:07:43,870 --> 00:07:49,710
+البني والغير طبيعية أيضا وجود فشل في اتصال وارتباط
+
+104
+00:07:49,710 --> 00:07:54,660
+الحيوان المنوي بالـ oocyte هذه الأمورتؤدي إلى فشل
+
+105
+00:07:54,660 --> 00:08:01,020
+عملية التلقيح الصناعي المعروف بالـ IVF لذلك نلجأ
+
+106
+00:08:01,020 --> 00:08:05,460
+إلى الـ IGC أيضًا الـ IGC مهم جدًا في الأشخاص
+
+107
+00:08:05,460 --> 00:08:10,480
+المصابين بالـ HIV أو الأشخاص المصابين بالـ
+
+108
+00:08:10,480 --> 00:08:15,420
+Hepatitis C Viral الناس المصابة بالـ HIV ما بتقدر
+
+109
+00:08:15,420 --> 00:08:19,400
+تنجب بشكل طبيعي هي بتنجب بشكل طبيعي ولكن ما بتقدر
+
+110
+00:08:19,400 --> 00:08:24,380
+تنجب babyطبيعي خالي من المرض فبتلجأ إلى التلقيح
+
+111
+00:08:24,380 --> 00:08:28,340
+الصناعي عشان يعمل عملية filtration و عملية washing
+
+112
+00:08:28,340 --> 00:08:32,760
+لل spermatozoa و التخلص من كل الانتجينات اللي لها
+
+113
+00:08:32,760 --> 00:08:37,520
+علاقة بال HIV فبحصل على single sperm pure بحكنه في
+
+114
+00:08:37,520 --> 00:08:41,380
+البويضة علشان أمنع انتقال هذا المرضFinally,
+
+115
+00:08:41,600 --> 00:08:46,520
+because only single spermatozoa is needed for each
+
+116
+00:08:46,520 --> 00:08:50,180
+egg, Eggsy has allowed the treatment of men who
+
+117
+00:08:50,180 --> 00:08:57,780
+are suffering from azoospermia أيضًا بعض ال male
+
+118
+00:08:57,780 --> 00:09:01,120
+بيعانوا من حالة بنسميها azoospermia وهذه ال
+
+119
+00:09:01,120 --> 00:09:05,530
+azoospermia عرفنا تعريفها في مصبق بمعنى آخرعنده
+
+120
+00:09:05,530 --> 00:09:09,450
+كمية قليلة جدا جدا جدا من عدد الحيوانات المنوية
+
+121
+00:09:09,450 --> 00:09:13,250
+تكاد تكون معدومة فبالتالي single sperm لو أنا
+
+122
+00:09:13,250 --> 00:09:16,970
+وجدته في المصنع يكفي لإنجاح حملية الحقن المجهري
+
+123
+00:09:16,970 --> 00:09:22,110
+فبالتالي بلجأ إلى البحث في المصنع عن طريق ال TSA
+
+124
+00:09:22,110 --> 00:09:25,470
+أو ال PISA ال blockage في ال main reproductive
+
+125
+00:09:25,470 --> 00:09:29,710
+tract may keep sperm from getting out فبالتالي
+
+126
+00:09:29,710 --> 00:09:34,660
+بلجأ إلى ال PISA أو ال TSA البدء في استخدامالـ
+
+127
+00:09:34,660 --> 00:09:37,880
+Immature Oocyte لأن الـ Immature Oocyte يمكن
+
+128
+00:09:37,880 --> 00:09:41,620
+انضاجة في المختبر فتصبح mature عندئذ أستطيع
+
+129
+00:09:41,620 --> 00:09:46,180
+استخدامها في عملية الحقن المجهري أيضًا الـ Oocyte
+
+130
+00:09:46,180 --> 00:09:50,680
+الزائدة عن الحاجة ممكن سيدة بعد ال response يصير
+
+131
+00:09:50,680 --> 00:09:54,520
+عندها very high فتعطيني 35 بوايدة مش منطقي ألقح ال
+
+132
+00:09:54,520 --> 00:09:58,240
+35 بوايدة بشكل كامل لأن مش هقدر أرجع إلى maximum
+
+133
+00:09:58,240 --> 00:10:03,150
+خمس أجنة أفضل خمس أجنة فبروح بخزنهذه البويضات
+
+134
+00:10:03,150 --> 00:10:08,830
+الزائدة إلى الـ Next Cycle فبحمي السيدة من عملية
+
+135
+00:10:08,830 --> 00:10:12,270
+ال stimulation التالية فبالتالي بقل العدد وكمية
+
+136
+00:10:12,270 --> 00:10:15,490
+الهرمونات و الحُقن التي تتناول السيدة من خلال
+
+137
+00:10:15,490 --> 00:10:20,450
+استخدام الـ Oocyte المجمدة طبعاً هذا كله أعطاني
+
+138
+00:10:20,450 --> 00:10:26,430
+فرصة لاستخدام الـ IGESI بدلاً عن ال IVF الـ IGESI
+
+139
+00:10:26,430 --> 00:10:32,260
+procedure بشكل عام تحتاج إلى Male و Femaleالمايل
+
+140
+00:10:32,260 --> 00:10:34,720
+بيخضع على الـ Sample Collection ثم الـ Sample
+
+141
+00:10:34,720 --> 00:10:37,040
+Preparation Sample Collection ثم Sample
+
+142
+00:10:37,040 --> 00:10:42,120
+Preparation علشان احصل على الـ Pure Spermatozoa من
+
+143
+00:10:42,120 --> 00:10:47,200
+خلال الـ Gradient من خلال الـ Simple Dilution أو
+
+144
+00:10:47,200 --> 00:10:50,520
+من خلال الـ Swamp Up أما في المايل بيخضع على
+
+145
+00:10:50,520 --> 00:10:54,420
+برنامج خاص بيسميه Ovarian Stimulation أو Ovarian
+
+146
+00:10:54,420 --> 00:10:57,640
+Hyper Stimulation أو Ovarian أو Control Ovarian
+
+147
+00:10:57,640 --> 00:11:02,800
+Stimulationحقنها بأنواع معينة من الهرمونات من أجل
+
+148
+00:11:02,800 --> 00:11:07,420
+زيادة استجابة المبيض لهذه الهرمونات مما يؤدي إلى
+
+149
+00:11:07,420 --> 00:11:12,900
+إخراج بويضات أكثر من حيث العدد إخراج بويضات أكثر
+
+150
+00:11:12,900 --> 00:11:16,980
+من حيث النضوج فبالتالي بيصير عندي فرصة أكثر وأكبر
+
+151
+00:11:16,980 --> 00:11:21,870
+لحقن أكبر عدد من البويضةThe semen sample is
+
+152
+00:11:21,870 --> 00:11:24,830
+prepared by centrifugation. The sperm should be
+
+153
+00:11:24,830 --> 00:11:27,850
+collected in special media. The separated sperm
+
+154
+00:11:27,850 --> 00:11:30,990
+should be separated from the live sperm from
+
+155
+00:11:30,990 --> 00:11:34,990
+depressed and most dead sperm هذه الـSperm Metazoa
+
+156
+00:11:34,990 --> 00:11:38,050
+اللي عملت لها عملية purification و washing لازم ال
+
+157
+00:11:38,050 --> 00:11:41,410
+life sperm والذي يستخدم في عملية الحقن المجهري
+
+158
+00:11:41,410 --> 00:11:45,530
+أفصلوا بشكل كامل عن كل ال depressed الموجودة وعن
+
+159
+00:11:45,530 --> 00:11:49,170
+كل ال dead sperm الموجودة عن كل ال immature sperm
+
+160
+00:11:49,170 --> 00:11:53,070
+الموجودة اللي سمناهاSpermato-Spermated فيما سابق
+
+161
+00:11:53,070 --> 00:11:56,510
+الـ Imperologists فيما بعد وظيفته انه يعمل
+
+162
+00:11:56,510 --> 00:12:00,670
+catching او pick up لل single life sperm ويعمله
+
+163
+00:12:00,670 --> 00:12:06,310
+عملية injection داخل البوادة علشان كده عملية الحقن
+
+164
+00:12:06,310 --> 00:12:10,850
+تحتاج الى two arms واحد اسمه holder بيبت holder
+
+165
+00:12:10,850 --> 00:12:14,610
+بيحمل فيه البيبت بيحمل فيه عفوا ال oocyte وبيكون
+
+166
+00:12:14,610 --> 00:12:18,530
+على اليسار في الغالب و injection needle بتكون على
+
+167
+00:12:18,530 --> 00:12:22,990
+اليمين في الغالبوكلهم mainly glass واحدة بتثبت
+
+168
+00:12:22,990 --> 00:12:27,730
+البوادة واحدة بتحمل ال sperm وبتعمل injection في
+
+169
+00:12:27,730 --> 00:12:32,110
+داخل البوادة هنشوفها بالصورة ان شاء الله جاب
+
+170
+00:12:32,110 --> 00:12:36,050
+المبدأ في عملية ال catching أو ال pick up of
+
+171
+00:12:36,050 --> 00:12:39,910
+spermatozoa في المحاضرات السابقة تكلمنا عن ال
+
+172
+00:12:39,910 --> 00:12:42,970
+semen parameter تكلمنا عن ال semen collection
+
+173
+00:12:42,970 --> 00:12:46,370
+تكلمنا عن ال purification method التلات أقسام
+
+174
+00:12:46,370 --> 00:12:51,820
+حالياًالعينة وصلتني كمختبر emperiologist as
+
+175
+00:12:51,820 --> 00:12:58,400
+spermatozoa pure يعني sperm life متحرك يصلح لعملية
+
+176
+00:12:58,400 --> 00:13:01,980
+ال IVF او عملية الحقن ال eggsy احنا بنتكلم عن ال
+
+177
+00:13:01,980 --> 00:13:06,060
+eggsy عشان اتم عملية ال eggsy لازم ابدأ بعملية
+
+178
+00:13:06,060 --> 00:13:10,080
+مهمة جدا اسمها eggsy dish preparation كيف يتم
+
+179
+00:13:10,080 --> 00:13:13,480
+تحضير أطباق الحقن ال majority طبق الحقن ال
+
+180
+00:13:13,480 --> 00:13:18,200
+majority هو طبق very sterile dishيشبه إلى حد ما
+
+181
+00:13:18,200 --> 00:13:22,180
+الأطباق الخاصة بالـ Microbiology ولكن أصغر من حيث
+
+182
+00:13:22,180 --> 00:13:27,780
+الحجب تكون معقمة بشكل كامل لا تستخدم ولا تفتح إلا
+
+183
+00:13:27,780 --> 00:13:32,540
+عند الاستخدام رغم أن بعض الدراسات تقولك يجب فتح ال
+
+184
+00:13:32,540 --> 00:13:37,040
+bucket الخاص بال dish ال Exidish علشان يطلع منها
+
+185
+00:13:37,040 --> 00:13:41,160
+ال volatile gas لأن بقاءه بيأثر سلبا على الجنين
+
+186
+00:13:41,160 --> 00:13:45,020
+فماشي بنفتحها و بنخليها في درج و في مكان معقم و
+
+187
+00:13:45,020 --> 00:13:48,430
+عند الحجب ناخد الطبقفي sterile condition، sterile
+
+188
+00:13:48,430 --> 00:13:52,870
+media، داخل ال safety cabinet نضع داخل الطبق تمان
+
+189
+00:13:52,870 --> 00:13:57,210
+قطرات أو تسع قطرات، في الغالب تسع قطرات تمانية على
+
+190
+00:13:57,210 --> 00:14:02,210
+المحيط وواحدة في المنتصف فبالتالي، nine drops
+
+191
+00:14:02,210 --> 00:14:05,790
+contained eight microliter of injection media are
+
+192
+00:14:05,790 --> 00:14:09,210
+replaced in the Petri dish with one in the center
+
+193
+00:14:09,210 --> 00:14:13,830
+and the rest around this dropيعني بمعنى أخر باخد
+
+194
+00:14:13,830 --> 00:14:16,470
+تمانية microliter و بعض الأحيان عشرة microliter
+
+195
+00:14:16,470 --> 00:14:21,710
+بضع تسع نقاط واحدة في المنتصف و تمانية حوالها كل
+
+196
+00:14:21,710 --> 00:14:25,290
+نقطة فيها من تمانية لعشرة microliter من ال
+
+197
+00:14:25,290 --> 00:14:30,230
+injection media طب ليش حطيت نقطة في المنتصف؟ وإيش
+
+198
+00:14:30,230 --> 00:14:34,210
+وظيفة التمانية الموجودة على الحواف؟ التمانية
+
+199
+00:14:34,210 --> 00:14:38,610
+الموجودة على الدائر و الحواف هي المسئولة عن أو
+
+200
+00:14:38,610 --> 00:14:42,440
+المكان الذي سوف نضع فيه البوايضاتبعد عملية الـ
+
+201
+00:14:42,440 --> 00:14:45,500
+Denodation اللي أخدناها فيه من السبب أما القطرة
+
+202
+00:14:45,500 --> 00:14:49,000
+الموجودة في المنتصف هي اللتي سنحمل فيها ال
+
+203
+00:14:49,000 --> 00:14:53,500
+spermatozoa فبالتالي بصير هندي 8 قطرات لو وضعت في
+
+204
+00:14:53,500 --> 00:14:57,180
+كل قطرة بوايدة هي 8 بوايدات في كل قطرة بوايدتين هي
+
+205
+00:14:57,180 --> 00:15:01,240
+16 بوايدة وقطرة في المنتصف تحتوي على ال
+
+206
+00:15:01,240 --> 00:15:05,380
+spermatozoa اللتي سوف تستخدم في عملية الحطب ال
+
+207
+00:15:05,380 --> 00:15:09,600
+drop should be close togetherفي فترة المسافة بينهم
+
+208
+00:15:09,600 --> 00:15:13,740
+لا تتجاوز الـ 20 ميلي متر لتسيل عملية الانتقال من
+
+209
+00:15:13,740 --> 00:15:17,520
+قطرة إلى قطرة و لازم تكون على heat stage درجة
+
+210
+00:15:17,520 --> 00:15:22,420
+حرارته و ليس في درجة حرارة جسم الإنسان 37 the
+
+211
+00:15:22,420 --> 00:15:27,300
+drops should be then over lied with oil to prevent
+
+212
+00:15:27,300 --> 00:15:31,600
+evaporation طبعا بعد مضيف القطرات لازم أخط القطرات
+
+213
+00:15:31,600 --> 00:15:36,740
+و أغمر القطرات ب oilعشان أمنع عملية ال evaporation
+
+214
+00:15:36,740 --> 00:15:41,460
+و أحافظ على الجميط بعد إضافتها فيما بعد طبعا أضيف
+
+215
+00:15:41,460 --> 00:15:45,400
+oil ولا أضيف الجميطات قبل؟ لأ بضيف التسعة قطارات و
+
+216
+00:15:45,400 --> 00:15:49,240
+بعدين بضيف oil بعد كده تكون جاهزة لإضافة الجميط
+
+217
+00:15:49,240 --> 00:15:53,960
+طبعا فيما بعد بستخدم ال marker علشان أعلم عند
+
+218
+00:15:53,960 --> 00:15:57,180
+الساعة 12 و هي عبارة عن ال position اللي حد قعد
+
+219
+00:15:57,180 --> 00:16:00,920
+منهو دايما بعد في عكس عقارب الساعة انت بتعد في
+
+220
+00:16:00,920 --> 00:16:04,700
+اتجاه عقارب الساعة عكس عقارب الساعة بما ترتقيه
+
+221
+00:16:04,700 --> 00:16:07,760
+يعني في ناس دايما الترقيم يكون عكس عقارب الساعة
+
+222
+00:16:07,760 --> 00:16:11,240
+فبالتالي القطرة اللي بتكون عند الساعة 12 برقمها 1
+
+223
+00:16:11,240 --> 00:16:16,840
+و ببدأ عكس عقارب الساعة ثم بعد ذلك أقوم بإغلاق
+
+224
+00:16:16,840 --> 00:16:21,660
+الطبق يكون كده جاهز لعملية تحميل الجميطات فيه أضعه
+
+225
+00:16:21,660 --> 00:16:25,600
+في ال incubator على درجة حرارة 37 درجة مئوية لكي
+
+226
+00:16:25,600 --> 00:16:30,120
+تتأقلم مع ال atmosphereالمتعلق بالـ Incubator
+
+227
+00:16:30,120 --> 00:16:36,260
+طبعاً هذا شكل الـ Petri dish في الغالب هذا شكل الـ
+
+228
+00:16:36,260 --> 00:16:39,820
+Petri dish طبعا هذه في الغالب هي عبارة عن
+
+229
+00:16:39,820 --> 00:16:43,960
+injection needle وهذه الـ holder pipette هذه
+
+230
+00:16:43,960 --> 00:16:48,140
+القطرة الموجودة في المنتصف هي حوالي 8 قطرات 1 2 3
+
+231
+00:16:48,140 --> 00:16:54,150
+4 5 6 7 8 أي شكل تاني من الأشكال المستخدمةهي
+
+232
+00:16:54,150 --> 00:16:56,770
+القطرة الموجودة في المنتصف هذه اللي بعلّب عليها
+
+233
+00:16:56,770 --> 00:17:01,670
+أنا هنا و حواليها ال line أحمر هعمل hold .. هعمل
+
+234
+00:17:01,670 --> 00:17:08,190
+عملية loading ل ال spare mat و ذوها و التمانية
+
+235
+00:17:08,190 --> 00:17:11,770
+المنتصف هعمل عملية loading ل ال bit .. لل OO site
+
+236
+00:17:11,770 --> 00:17:15,170
+بعد عملية ال donation .. بعد عملية ال donation
+
+237
+00:17:15,170 --> 00:17:20,250
+دلنا نشوف كيف بتم تحضير الطبق بالطريقة اللي
+
+238
+00:17:20,250 --> 00:17:21,970
+اتكلمنا فيها قبل بشوية
+
+239
+00:17:25,390 --> 00:17:28,050
+طبعاً هنا هي الطبق بالـ dropper, sterile dropper
+
+240
+00:17:28,050 --> 00:17:32,490
+بضيف القطرات المطلوبة في بعضهم بضيفها على شكل line
+
+241
+00:17:32,490 --> 00:17:37,110
+في بعضهم بضيفها على شكل دائرة كلاهم صح انت شو
+
+242
+00:17:37,110 --> 00:17:41,290
+بترتأي و شو بترتاح تشتغل ولكن الصح انك تضيفهم على
+
+243
+00:17:41,290 --> 00:17:46,530
+شكل دائرة بعدين ضاف حوالهم ال oil طبعاً هنا ضاف
+
+244
+00:17:46,530 --> 00:17:50,910
+أربع قطرات و غطاهم بال oil و ال oil لازم يغطي
+
+245
+00:17:50,910 --> 00:17:56,200
+الطبق ككل عشان شو؟ عشان أمنععملية ال evaporation
+
+246
+00:17:56,200 --> 00:18:01,380
+جهز الطبق بتحمل عليها الجاميطات و لما أقول جاميط
+
+247
+00:18:01,380 --> 00:18:05,600
+يعني male جاميط و female جاميط لازم أحمل ال male و
+
+248
+00:18:05,600 --> 00:18:10,560
+ال female بعد مباشرة immediately before injection
+
+249
+00:18:10,560 --> 00:18:14,300
+and under stereomicroscope the centered drop
+
+250
+00:18:14,300 --> 00:18:17,980
+should be removed and replaced with one microliter
+
+251
+00:18:17,980 --> 00:18:25,450
+of sperm suspendedDiluted in 4µL of 7% PVB ماعرفش
+
+252
+00:18:25,450 --> 00:18:28,170
+يعني PVB شو معنى الكلام هذا ببساطة جدا بيقول
+
+253
+00:18:28,170 --> 00:18:32,030
+القطرة اللي توضعتها في المتصف و هي رقم 9 بتزيلها
+
+254
+00:18:32,030 --> 00:18:39,930
+أو تستبدلها ب 1µL من ال spermatozoa اللي تم
+
+255
+00:18:39,930 --> 00:18:45,890
+تخفيفها في 4µL من ال PVB يعني كأنه بيقولك ببساطة
+
+256
+00:18:45,890 --> 00:18:51,060
+جدا بتجيب 1µL من ال spermatozoaاللي حضرتها عن طريق
+
+257
+00:18:51,060 --> 00:18:56,300
+الـ Gradient أو حضرتها عن طريق Swamp Up وبتعملها
+
+258
+00:18:56,300 --> 00:19:01,820
+Mixing في 4 ملي لتر من ميديا تركيزها 7% تسمى PVP
+
+259
+00:19:01,820 --> 00:19:06,020
+الـ Total Volume 5 تاخد الخمسة micro وبضيفها مكان
+
+260
+00:19:06,020 --> 00:19:09,680
+القطرة الموجودة في المنتصف مش كده في البداية قلت
+
+261
+00:19:09,680 --> 00:19:12,240
+القطرة التاسعة الموجودة في المنتصف هي القطرة اللتي
+
+262
+00:19:12,240 --> 00:19:14,760
+يحمل عليها spermatozoon
+
+263
+00:19:17,710 --> 00:19:20,650
+باستخدام الـ Pasteur Pipet أو Plastic Pipet بتكون
+
+264
+00:19:20,650 --> 00:19:24,010
+ضمن ديامتر معين باجي بانقل البويضات اللي عملتي لها
+
+265
+00:19:24,010 --> 00:19:28,110
+denotation و بضع في كل قطرة الموجودة على الجوانب
+
+266
+00:19:28,110 --> 00:19:32,590
+بويضة أو بويضتين بناء على عدد البويضات اللي موجودة
+
+267
+00:19:32,590 --> 00:19:37,130
+عندي لإن هتصير أتحرك من المنتصف من القطرة اللتي
+
+268
+00:19:37,130 --> 00:19:40,310
+تحتوي على ال spermatozoa إلى القطرة اللتي تحتوي
+
+269
+00:19:40,310 --> 00:19:44,510
+على ال oocyteفمن المنتصف للخارج من المنتصف للخارج
+
+270
+00:19:44,510 --> 00:19:50,170
+عشان كده مهم جدا أحدد الساعة 12 وين هي طالما أحدد
+
+271
+00:19:50,170 --> 00:19:54,930
+الساعة 12 هي نقطة البداية نقطة البداية So what is
+
+272
+00:19:54,930 --> 00:20:00,430
+the function of BVB media during exit? The BVB
+
+273
+00:20:00,430 --> 00:20:03,710
+media has four function or three function The
+
+274
+00:20:03,710 --> 00:20:07,970
+first function reduce the motility of spermatozoa
+
+275
+00:20:08,430 --> 00:20:11,410
+أحنا بنعرف إنه sperm very fast فأنا بعمل عشان
+
+276
+00:20:11,410 --> 00:20:14,990
+أعمله catching بدي أعمله reducing للموتility عشان
+
+277
+00:20:14,990 --> 00:20:19,990
+أتحرك ببطء وأقدر أعمله catching و pick up نين بدي
+
+278
+00:20:19,990 --> 00:20:23,030
+أعمل ال preventing لل sticking في ال inner surface
+
+279
+00:20:23,030 --> 00:20:27,090
+من ال injection ال tube أنا لما أجي أمسك ال sperm
+
+280
+00:20:27,090 --> 00:20:30,430
+و أعمله suction ممكن ال sperm يلتصق بالجدار
+
+281
+00:20:30,430 --> 00:20:34,290
+الداخلي لل needle فانا بدي أمنع هذه العملية من
+
+282
+00:20:34,290 --> 00:20:40,140
+خلال استخدام ال BVB فبتعمل زيغشاء لاصق يمنع التصاق
+
+283
+00:20:40,140 --> 00:20:44,200
+للـ sperm بالـ inner service of injection needle
+
+284
+00:20:44,200 --> 00:20:47,840
+to give more control over the flow of fluid in the
+
+285
+00:20:47,840 --> 00:20:54,120
+exit أيضًا بسمح لي أن أتحكم بدخول وخروج ال sperm
+
+286
+00:20:54,120 --> 00:20:58,260
+بكل سهولة لأن الفسكوس التي تبعت ال BVP media إلى
+
+287
+00:20:58,260 --> 00:21:04,450
+حد عالية فبتتحرك بدرجة خفيفة من السرعة ما بتتحرك
+
+288
+00:21:04,450 --> 00:21:07,430
+بسرعة فبالتالي بفقد ال spirit بسرعة فبالتالي هذه
+
+289
+00:21:07,430 --> 00:21:13,410
+لزوجتها مهمة جدا في التحكم في عملية تدفق السائل أو
+
+290
+00:21:13,410 --> 00:21:18,930
+تدفق وحركة ال spirit ال media which is usually
+
+291
+00:21:18,930 --> 00:21:21,870
+present in the cultural media has the ability to
+
+292
+00:21:21,870 --> 00:21:25,250
+act as membrane and egg شو يعني ممبرين بعد egg
+
+293
+00:21:25,250 --> 00:21:30,190
+بقول ال media اللي أنا استخدمتهاواللي خلطت فيها
+
+294
+00:21:30,190 --> 00:21:34,150
+واحد microliter من ال sperm تستخدم كلاسق زي
+
+295
+00:21:34,150 --> 00:21:38,590
+plaster شو دخل ال plaster في الموضوع؟ في مصطلح
+
+296
+00:21:38,590 --> 00:21:43,210
+هناخده كمان شوية اسمه spermatozoa immobilization
+
+297
+00:21:43,210 --> 00:21:48,590
+يعني إعطاب الحيوان المنوي أو إفقاد قدر الحركة لدى
+
+298
+00:21:48,590 --> 00:21:51,690
+الحيوان المنوي كيف بتصير هذه؟ من خلال جرح الحيوان
+
+299
+00:21:51,690 --> 00:21:58,090
+المنوي أو قطع جزء لديل الخاص بحيوان المنوي لو أنا
+
+300
+00:21:58,580 --> 00:22:02,080
+عملت sharpening cutting في الـ tail of الـ
+
+301
+00:22:02,080 --> 00:22:05,820
+spermatozoa كل المادة الموجودة في ال sperm هتتدفق
+
+302
+00:22:05,820 --> 00:22:10,760
+في الخارج ولكن وجود ال BVP media بتعمل زي plaster
+
+303
+00:22:10,760 --> 00:22:15,200
+فبتمنع عملية التدفق وإلا أنا هفقد كل المواد
+
+304
+00:22:15,200 --> 00:22:18,980
+اللازمة لإتمام عملية ال fertilization وبكدا أنا
+
+305
+00:22:18,980 --> 00:22:23,340
+فقدت ال sperm عشان كده بقولك ان ال BVP media بتعمل
+
+306
+00:22:23,340 --> 00:22:28,870
+زي ال membrane or band aid يعنيالوثاقة الخاصة
+
+307
+00:22:28,870 --> 00:22:32,230
+بالإسعافات الأولين الـ Plasma Brain Damage induced
+
+308
+00:22:32,230 --> 00:22:36,650
+by the touching tail does not allow anything from
+
+309
+00:22:36,650 --> 00:22:39,610
+the sperm cell to leak into the surrounding media
+
+310
+00:22:39,610 --> 00:22:45,170
+أيضًا، الـ sperm cell بعد عملية ال- impolization،
+
+311
+00:22:45,170 --> 00:22:48,710
+بجد ال- immobilization عفوًا، بجد إن الـ sperm لا
+
+312
+00:22:48,710 --> 00:22:54,070
+تزوّايبقى قادر على إخصاب البويضة لفترة زمانية
+
+313
+00:22:54,070 --> 00:23:00,970
+تتراوح لعدد ساعات مش many hours .. several hours
+
+314
+00:23:00,970 --> 00:23:07,250
+هذا بعد ال game immobilization طيب حملت الحيوانات
+
+315
+00:23:07,250 --> 00:23:10,890
+المنوية في القطرس الموجودة في المنتصف حالياً هالجي
+
+316
+00:23:10,890 --> 00:23:14,090
+على نقطة تانية إن بتعمل catching للحيوان المنوي
+
+317
+00:23:14,090 --> 00:23:17,770
+لأن مش كل sperm أنا بدي أستخدمها بدي أستخدم
+
+318
+00:23:17,770 --> 00:23:21,430
+الحيوان المنويالـ morphological normal و بتحرك
+
+319
+00:23:21,430 --> 00:23:25,950
+بشكل طبيعي في مصطلح بنسميه catching the sperm كيف
+
+320
+00:23:25,950 --> 00:23:30,850
+بتعمل catching لل sperm؟ و أنا جاعت بعمل
+
+321
+00:23:30,850 --> 00:23:34,110
+denodation و خلصت؟ بتعمل catching of spermatozoa
+
+322
+00:23:34,110 --> 00:23:39,150
+من خلال أني أسحب تلاتة أربعة sperm و أعملهم
+
+323
+00:23:39,150 --> 00:23:43,850
+immobilization شو يعني immobilization؟ يعني إعطاب
+
+324
+00:23:43,850 --> 00:23:49,470
+و فقدان الحركة من خلال جرح ال spermSince in most
+
+325
+00:23:49,470 --> 00:23:52,610
+of patients specific percentage of sperm is
+
+326
+00:23:52,610 --> 00:23:55,950
+motile, embryologists are faced with the problem
+
+327
+00:23:55,950 --> 00:24:00,450
+of catching this gamete before to immobilization
+
+328
+00:24:00,450 --> 00:24:03,570
+and injection يعني أول مشكلة بتواجهني ك
+
+329
+00:24:03,570 --> 00:24:09,130
+embryologist كيف أستطيع أن أمسك هذا الجاميت أو هذه
+
+330
+00:24:09,130 --> 00:24:13,530
+الجامتات الذكرية ليه المشكلة؟ لأن الحيوان حكيت أنه
+
+331
+00:24:13,530 --> 00:24:17,640
+بتحرك بسرعة فما بقدر أتحكم فيهفبدّي شيء يعمل
+
+332
+00:24:17,640 --> 00:24:21,880
+reduction لـ motility وinhibition وهي الـ BVP
+
+333
+00:24:21,880 --> 00:24:25,360
+media شو ال media أو ال procedure can be performed
+
+334
+00:24:25,360 --> 00:24:31,500
+in the different .. خلّيني أسميها type of media زي
+
+335
+00:24:31,500 --> 00:24:35,340
+ال culture media in general ال BVP media وحاجة
+
+336
+00:24:35,340 --> 00:24:38,860
+بتسميها more physiological viscous solution يعني
+
+337
+00:24:38,860 --> 00:24:44,860
+هذه تلت أمور مهمة جدا تلقى دور كبير في اختزاد حركة
+
+338
+00:24:44,860 --> 00:24:49,550
+الحيوانتثير عملية الـ catching أو الـ pick-up للـ
+
+339
+00:24:49,550 --> 00:24:52,510
+spermatozoa الـ PVV media الـ physiological
+
+340
+00:24:52,510 --> 00:24:57,390
+viscous media و الـ cultured media loading process
+
+341
+00:24:57,390 --> 00:25:01,350
+sperm sample into media drop on the exodash has
+
+342
+00:25:01,350 --> 00:25:04,930
+the benefit that motile sperm will automatically
+
+343
+00:25:04,930 --> 00:25:08,670
+separated from immotile gamete, somatic cell and
+
+344
+00:25:08,670 --> 00:25:13,390
+other debris انت بمجرد ما تخلط واحد microliter من
+
+345
+00:25:13,390 --> 00:25:17,350
+ال spermatozoa بعد ال swarm upمع أربعة من PVP
+
+346
+00:25:17,350 --> 00:25:20,610
+تركيزة سبعة وتحميلها في القطرة الموجودة في الـ
+
+347
+00:25:20,610 --> 00:25:24,530
+center هذا سرعان ما يساعد الـ sperm أن يصير
+
+348
+00:25:24,530 --> 00:25:28,950
+separation between normal sperm, live sperm and
+
+349
+00:25:28,950 --> 00:25:32,990
+other type of spermatozoa and the breast هذا يعني
+
+350
+00:25:32,990 --> 00:25:38,910
+خطوة إضافية من ناحية ال purification this make the
+
+351
+00:25:38,910 --> 00:25:43,010
+purity of whole drop much higher and minimized the
+
+352
+00:25:43,010 --> 00:25:46,850
+contamination theoreticallyيعني هذه الخطوة عملية
+
+353
+00:25:46,850 --> 00:25:53,070
+الـ mixing بتقلل الـ motility وبتقلل أي خطأ ولو
+
+354
+00:25:53,070 --> 00:25:56,430
+كانت خطأ نظري أو contamination بشكل نظري however
+
+355
+00:25:56,430 --> 00:26:00,410
+this mood of catching spear has the drawback that
+
+356
+00:26:00,410 --> 00:26:03,250
+without viscous solution covering the inner
+
+357
+00:26:03,250 --> 00:26:06,030
+surface of the injection pipet spear manipulation
+
+358
+00:26:06,030 --> 00:26:11,410
+during injection is not smoothly عدم وجود solution
+
+359
+00:26:11,410 --> 00:26:16,000
+داخل injection needle الفسكوس تبعته عاليةمعناه ال
+
+360
+00:26:16,000 --> 00:26:19,620
+catching لل spare مش هتكون سهلة مش هتكون لطيفة مش
+
+361
+00:26:19,620 --> 00:26:24,060
+هتكون بالصورة just game لأ هتتغلر فيها بشكل كبير
+
+362
+00:26:24,060 --> 00:26:29,160
+جدا و أي حركة و لو كانت حركة عبثية أو غير محسوبة
+
+363
+00:26:29,160 --> 00:26:32,740
+هضيع ال spare فالمبالك لو أنت بتشتغل على عين مافيش
+
+364
+00:26:32,740 --> 00:26:36,400
+فيها الله أربع spare أربع spare ماتو زواج this
+
+365
+00:26:36,400 --> 00:26:39,940
+problem cannot be overcome but it can be reduced
+
+366
+00:26:39,940 --> 00:26:47,740
+by washing the xyz tool by pvpأي العملية هذه عشان
+
+367
+00:26:47,740 --> 00:26:51,520
+أقلل الخطأ اللي فيها و أتحكم بالـ spermatozoa و ال
+
+368
+00:26:51,520 --> 00:26:54,880
+aspiration للـ spermatozoa بشكل كبير جدا و أمنع ال
+
+369
+00:26:54,880 --> 00:26:59,360
+contamination و أتحكم بال follow و تضفق السائل
+
+370
+00:26:59,360 --> 00:27:02,940
+خلال عملية ال injection أو ال aspiration لازم أغسل
+
+371
+00:27:02,940 --> 00:27:08,000
+ال media عفوا أغسل ال tools الخاصة بال exit tools
+
+372
+00:27:08,000 --> 00:27:11,380
+زي ال holder و ال injection بال BVB media كيف
+
+373
+00:27:11,380 --> 00:27:14,780
+أغسلهم؟ بعمل aspiration و releasing sucking و
+
+374
+00:27:14,780 --> 00:27:19,280
+releasingكإن أنا بخسلها من الداخل it is
+
+375
+00:27:19,280 --> 00:27:22,660
+recommended that minimum volume of media is placed
+
+376
+00:27:22,660 --> 00:27:26,740
+in the exit pipet and that sperm is placed in the
+
+377
+00:27:26,740 --> 00:27:30,040
+foremost third of visible part of a glass tool بعد
+
+378
+00:27:30,040 --> 00:27:32,360
+أن انت ماتعمل aspiration و releasing suction و
+
+379
+00:27:32,360 --> 00:27:36,540
+releasing لل PVP media داخل injection needle و ال
+
+380
+00:27:36,540 --> 00:27:40,040
+holder pipet بعد كده تبقى ال catching لل sperm
+
+381
+00:27:40,040 --> 00:27:44,960
+بسهولة و خدوا بالكوا ال catching لل spermلازم انا
+
+382
+00:27:44,960 --> 00:27:47,680
+بعد ما اعمل catching و ادخل ال sperm داخل ال
+
+383
+00:27:47,680 --> 00:27:51,200
+needle لازم يضغوا ال sperm تحت النظر كافي تضغط تحت
+
+384
+00:27:51,200 --> 00:27:54,780
+النظر نص ال needle بتكون ظهرة في ال microscope
+
+385
+00:27:54,780 --> 00:27:59,500
+فلازم يكون ال sperm في التلت الأول من ال needle
+
+386
+00:27:59,500 --> 00:28:03,740
+عشان اتأكد ان ال sperm موجود في ال needle بعد كده
+
+387
+00:28:03,740 --> 00:28:07,800
+ال embryologist في عنده مشكلة هل يسحب ال sperm من
+
+388
+00:28:07,800 --> 00:28:11,510
+ال head؟ولا يسحب ال sperm من ال tail لما أنا بدأ
+
+389
+00:28:11,510 --> 00:28:15,710
+أسحب ال sperm لأول مرة عشان أحوله لخطوة ال
+
+390
+00:28:15,710 --> 00:28:20,030
+immobilization بسحبه من ال head لأنه أسهل تصور إن
+
+391
+00:28:20,030 --> 00:28:23,870
+عندك sperm ال head كبير واضح و ال tail متحرك تمسكه
+
+392
+00:28:23,870 --> 00:28:26,410
+من ال tail ولا تمسكه من ال head لأ أنا بعمله
+
+393
+00:28:26,410 --> 00:28:30,110
+suction من ال head لأنه أسهل بعد ما أعمله
+
+394
+00:28:30,110 --> 00:28:33,330
+immobilization بعمله suction من ال tail لأن ال
+
+395
+00:28:33,330 --> 00:28:39,280
+tail فقد قدرته على الحركةفي مشكلة تانية بتواجهني
+
+396
+00:28:39,280 --> 00:28:45,600
+أنه لما أجي أعمل injection بلاقي أن جزء من ال PVP
+
+397
+00:28:45,600 --> 00:28:48,700
+media الموجود داخل ال injection needle قد يدخل إلى
+
+398
+00:28:48,700 --> 00:28:52,920
+الـCytoplasm القصب الـOocyte وإذا أنت ما كنتش صاحي
+
+399
+00:28:52,920 --> 00:28:57,160
+للموضوع ده كمية كبيرة جدا تدخل للـOocyte Cytoplasm
+
+400
+00:28:57,160 --> 00:29:01,800
+فده بيعمل مشاكل خلال عملية تطور الـOocyte الملقحة
+
+401
+00:29:01,800 --> 00:29:06,650
+وانقسمها طب ليه بيعمل مشاكل؟ لأن مجلد densityو الـ
+
+402
+00:29:06,650 --> 00:29:11,430
+Size تبع جزيئات الـ PVP Media كبيرة إلى حد ما فما
+
+403
+00:29:11,430 --> 00:29:15,110
+تستطيع الـ Oocyte تتخلص منها من خلال القنوات
+
+404
+00:29:15,110 --> 00:29:18,470
+الموجودة في الـ Plasma Membrane الخاصة بالـ Oocyte
+
+405
+00:29:18,470 --> 00:29:23,350
+عشان كده لازم تكون حذر و ما تتنزل كمية كبيرة جدا
+
+406
+00:29:23,350 --> 00:29:27,910
+أو تدخل كمية كمية كبيرة جدا من الـ PVP Media داخل
+
+407
+00:29:27,910 --> 00:29:31,690
+الـ Oocyte إلا بالحد القليل المسموع طب كيف ده
+
+408
+00:29:31,690 --> 00:29:37,660
+بتصير؟ ببساطة جدا لما انتيجت تخترقجبل ما تخترق
+
+409
+00:29:37,660 --> 00:29:43,160
+البويضة هتنزل ال sperm إلى أقرب نقطة من فوهة ال
+
+410
+00:29:43,160 --> 00:29:47,920
+injection needle وبعدين تخترق البويضة هتسحب جزء
+
+411
+00:29:47,920 --> 00:29:51,680
+بسيط من ال cytoplasm عشان تتأكد أنك داخل ال oocyte
+
+412
+00:29:51,680 --> 00:29:56,180
+مش خرقت من ال أو تم اختراق ال oocyte من جانب وخرجت
+
+413
+00:29:56,180 --> 00:30:01,040
+من الجانب الآخر إذا سحبت ال cytoplasm وتأكدت أن ال
+
+414
+00:30:01,040 --> 00:30:04,500
+cytoplasm سحب قدامك وتشافت تحت ال microscope معناه
+
+415
+00:30:04,500 --> 00:30:09,600
+أنتداخل الـ Oocyte هتعمل releasing للـ sperm أول
+
+416
+00:30:09,600 --> 00:30:13,640
+ما الـ sperm ينزل من ال injection needle هترفع
+
+417
+00:30:13,640 --> 00:30:19,720
+وتعمل عملية removing لل injection needle من الـ
+
+418
+00:30:19,720 --> 00:30:24,500
+cytoplasm فبالتالي بتكون كميات ضئيلة جدا من ال BVP
+
+419
+00:30:24,500 --> 00:30:28,800
+media الموجودة بداخل ال injection needle وفرغت
+
+420
+00:30:28,800 --> 00:30:32,100
+داخل الـ Oocyte فبالتالي تأثيرها بيكون إلى حد ما
+
+421
+00:30:32,100 --> 00:30:38,850
+محدود أو معدومطيب كيف انا بدأ اعمل عملية ال
+
+422
+00:30:38,850 --> 00:30:41,950
+catching؟ في عندى طريقتين الطريقة الأولى بيسموها
+
+423
+00:30:41,950 --> 00:30:45,390
+sperm slow و الطريقة التانية بيسموها sperm
+
+424
+00:30:45,390 --> 00:30:50,550
+catching طبعا كلاهم او كلا الطريقتين باعتمدوا على
+
+425
+00:30:50,550 --> 00:30:55,830
+مبدأ واحد وهو عبارة عن ما يليه the major compound
+
+426
+00:30:55,830 --> 00:31:01,740
+of the cumulus cell matrix هي لورينيتslow down to
+
+427
+00:31:01,740 --> 00:31:05,160
+move the spermatozoa and could act as natural
+
+428
+00:31:05,160 --> 00:31:10,540
+alternative to PVP وجدوا أن الـ Oocyte خلاياها
+
+429
+00:31:10,540 --> 00:31:14,740
+تحتوي على كمية كبيرة جدا cumulus cell matrix تحتوي
+
+430
+00:31:14,740 --> 00:31:18,920
+على مركب طبيعي يسمى هي لورينيت وهذا اللي هي
+
+431
+00:31:18,920 --> 00:31:24,340
+لورينيت يلعب ضوء كبير جدا في انقاص واخفاض واختزان
+
+432
+00:31:24,340 --> 00:31:29,980
+الحركة لدى ال spermatozoa فبالتالي أستطيع استخدام
+
+433
+00:31:30,660 --> 00:31:35,220
+دم هذا المُركّب الطبيعي بدلاً من الـ PVP media
+
+434
+00:31:35,220 --> 00:31:40,100
+اللي هي لورينايت relatively high negative charge
+
+435
+00:31:40,100 --> 00:31:44,680
+and high hydration capacity which allow for the
+
+436
+00:31:44,680 --> 00:31:47,500
+preparation of solution with adequate viscosity
+
+437
+00:31:47,500 --> 00:31:52,940
+for exit ليه السبب أو شو السبب اللي خلّه اللي هي
+
+438
+00:31:52,940 --> 00:31:59,140
+لورينايت مقابل أو عوض عن ال PVP أو alternative لل
+
+439
+00:31:59,140 --> 00:32:03,820
+PVP عدة أسبابمنه الـ Negative Charge منه أن الـ
+
+440
+00:32:03,820 --> 00:32:08,140
+Hydration كبسطة عالية جدا كلاهم يمنحن القدرة
+
+441
+00:32:08,140 --> 00:32:14,080
+بالتكوين محلول فسكوسية تبعته عالية أو كافية لإعاقط
+
+442
+00:32:14,080 --> 00:32:17,800
+حركة الـ spermatozoa والتحكم بشكل كبير في عملية
+
+443
+00:32:17,800 --> 00:32:21,940
+التضافق It has been reported that its effect on
+
+444
+00:32:21,940 --> 00:32:26,020
+the sperm motility is reversible يعني تأثير
+
+445
+00:32:26,020 --> 00:32:28,840
+الهيوروناية تأضف إلى ذلك تأثيره على ال spermatozoa
+
+446
+00:32:28,840 --> 00:32:33,420
+مش دائمreversible مش irreversible لأ reversible
+
+447
+00:32:33,420 --> 00:32:41,560
+يعني عكسي and is used and it is used and it is
+
+448
+00:32:41,560 --> 00:32:44,260
+used does not affect the outcome of treatment
+
+449
+00:32:44,260 --> 00:32:47,380
+cycle in term fertilization pregnancy and live
+
+450
+00:32:47,380 --> 00:32:51,280
+birth rate بمعنى أخر رغم أنه تأثيره على ال sperm
+
+451
+00:32:51,280 --> 00:32:55,440
+motility تأثير ليس بدائم أيضا الدراسات جالت ما
+
+452
+00:32:55,440 --> 00:32:58,000
+بتأثر على ال pregnancy rate ما بتأثر على ال
+
+453
+00:32:58,000 --> 00:33:01,460
+fertilization rateما بتأثر على معدل الحصول على
+
+454
+00:33:01,460 --> 00:33:06,920
+life pairs وهذا شيء مهم جدا خلال عملية الإجذب وال
+
+455
+00:33:06,920 --> 00:33:11,660
+injection سنكتفي بهذا القدر في هذه المحاضرة على أن
+
+456
+00:33:11,660 --> 00:33:16,780
+نلتقي في محاضرة جديدة ان شاء الله دومتم في حفظ
+
+457
+00:33:16,780 --> 00:33:19,140
+الله والسلام عليكم ورحمة الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/9mspvrq6uv4_postprocess.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/9mspvrq6uv4_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..97cd2044a73726b074c8a4d8a408f9c1a2a6d19d
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/9mspvrq6uv4_postprocess.srt
@@ -0,0 +1,2596 @@
+1
+00:00:00,570 --> 00:00:04,290
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:04,290 --> 00:00:09,550
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا
+
+3
+00:00:09,550 --> 00:00:13,330
+الأعزاء نرجو من الله الكريم أن تكونوا جميعا بخير
+
+4
+00:00:13,330 --> 00:00:18,670
+وبصحة جيدة تحدثنا في المحاضرة السابقة عن فحص يعتبر
+
+5
+00:00:18,670 --> 00:00:22,550
+من أهم الفعوصات التي تستخدم في تقييم قدرة الرجل
+
+6
+00:00:22,550 --> 00:00:26,650
+على الإنجاب وهو فحص تحليل السائل المنوي تحت مصطلح
+
+7
+00:00:26,650 --> 00:00:31,760
+Seminal Analysis قررناخلال الحديث عن هذا الفحص عن
+
+8
+00:00:31,760 --> 00:00:37,540
+عدة معايير مهمة كالـ volume الـ pH الفسكوسيتي الـ
+
+9
+00:00:37,540 --> 00:00:41,540
+concentration الـ count الـ motility بأقسامها
+
+10
+00:00:41,540 --> 00:00:45,280
+متمثلة في الـ progressive motile الـ non
+
+11
+00:00:45,280 --> 00:00:48,120
+progressive motile الـ non motile spermatozoa
+
+12
+00:00:48,120 --> 00:00:51,820
+انتقلنا للحديث عن الـ morphology انتقلنا للحديث عن
+
+13
+00:00:51,820 --> 00:00:56,060
+بعض الفحوصات المتعلقة بنشاط الـ sperm زي الـ
+
+14
+00:00:56,060 --> 00:01:00,070
+fructose test هذه معظمها فحوصاتلها علاقة بالـ
+
+15
+00:01:00,070 --> 00:01:04,610
+Seminal Fluid جميعها يتم إجراءها و يتم إنجازها في
+
+16
+00:01:04,610 --> 00:01:09,990
+المختبر وبعضها لا يتم تطرق إليها مثل فحص الفرقتوز
+
+17
+00:01:09,990 --> 00:01:15,350
+على سبيل المثال اليوم سوف نتحدث عن موضوع جديد له
+
+18
+00:01:15,350 --> 00:01:19,930
+علاقة بالآلية المتبعة و الطرق المستخدمة لتحضير
+
+19
+00:01:19,930 --> 00:01:24,170
+عينة الساقل للحقن المجهري أو للتلقيح الصناعي
+
+20
+00:01:24,170 --> 00:01:30,490
+التقليدي المسمى باسمIVF In Vitro Fertilization
+
+21
+00:01:30,490 --> 00:01:36,590
+ولكن قبل أن نتحدث عن هذه الآليات وهذه الطرق التي
+
+22
+00:01:36,590 --> 00:01:40,890
+يمكن أن تستخدم من أجل تحضير عينة السائل دعونا
+
+23
+00:01:40,890 --> 00:01:45,750
+نتكلم عن مصالحات طبية مهمة جداً لها علاقة بالـ XY
+
+24
+00:01:45,750 --> 00:01:51,510
+ولها علاقة بالـ Seminal Fluid من أشهرها Aspermia
+
+25
+00:01:51,510 --> 00:01:56,170
+فالـ Aspermia معناها أنعدم وجود seminal fluid هذا
+
+26
+00:01:56,170 --> 00:02:00,350
+الرجل لا يستطيع أن يعمل ejaculation فبالتالي في
+
+27
+00:02:00,350 --> 00:02:03,390
+عنده seminal fluid ال volume الخاص فيه zero مافي
+
+28
+00:02:03,390 --> 00:02:07,770
+عنده seminal أو semen volume مافي عنده semen
+
+29
+00:02:07,770 --> 00:02:12,150
+volume so the definition of a spermia is no
+
+30
+00:02:12,150 --> 00:02:17,190
+seminal fluid وينطبق عليها مصطلحين hypospermia
+
+31
+00:02:17,190 --> 00:02:21,120
+وhyperspermiaالـ Hyper-Spermia زيادة في الـ volume
+
+32
+00:02:21,120 --> 00:02:26,660
+في الحجم بيتجاوز الـ 5.5 ملي لتر أما الـ Hypo
+
+33
+00:02:26,660 --> 00:02:31,780
+-Spermia نقصان في الـ volume لكي يكون أقل من 2 ملي
+
+34
+00:02:31,780 --> 00:02:35,240
+لتر لأننا اتفقنا أن الـ normal volume للـ seminal
+
+35
+00:02:35,240 --> 00:02:40,820
+fluid 2 ملي لتر فزيادته و نقصانه له مصطلح معين
+
+36
+00:02:40,820 --> 00:02:46,400
+يليه مصطلح مهم جدا و هو أكثر انتشارا هو عبارة عن
+
+37
+00:02:46,400 --> 00:02:50,530
+الـ Oligospermiaالـ Ologospermia معناها نقصان في
+
+38
+00:02:50,530 --> 00:02:54,410
+عدد الحيوانات المنوية في كل واحد مليليتر لكي تصل
+
+39
+00:02:54,410 --> 00:02:59,590
+إلى أقل من 20 مليون حيوان في المليلتر الواحد يليه
+
+40
+00:02:59,590 --> 00:03:04,150
+مصطلح مهم ويعتبر من المصطلحات الأكثر انتشارا و
+
+41
+00:03:04,150 --> 00:03:08,170
+الأهم وهي مصطلح الـ Azospermia فالـ Azospermia
+
+42
+00:03:08,170 --> 00:03:12,350
+معناها عدم وجود سبيرماتوزوة في الـ seminal fluid
+
+43
+00:03:12,350 --> 00:03:18,070
+so the leak of sperm in the semen جدش بتتمثلهذه
+
+44
+00:03:18,070 --> 00:03:23,390
+العملية وهذا المصطلح مصطلح الازوسبيرميا يمثل 2% أو
+
+45
+00:03:23,390 --> 00:03:29,170
+يتواجد بمعدل 2% من ال total males population يعني
+
+46
+00:03:29,170 --> 00:03:33,870
+بمعنى أخر كل 100 male وكل 100 men فيهم اتنين
+
+47
+00:03:33,870 --> 00:03:38,070
+مصابين بالازوسبيرميا أيضا وجدوا ان الازوسبيرميا
+
+48
+00:03:38,070 --> 00:03:43,490
+تتواجد بمعدل 10-15% من الذكور المشخصين بأنهم
+
+49
+00:03:43,490 --> 00:03:47,710
+infertile هذا المصطلح مصطلحمهم وخاطير في نفس
+
+50
+00:03:47,710 --> 00:03:51,790
+اللحظة خدوا بالك في مصطلحين انهم علاقة بال
+
+51
+00:03:51,790 --> 00:03:56,070
+asospermia asospermia as general term و asospermia
+
+52
+00:03:56,070 --> 00:04:02,230
+after centrifugation ال asospermia as general term
+
+53
+00:04:02,230 --> 00:04:05,490
+انه تكنولوجيست عامل scanning للشريحة مالجاش فيها
+
+54
+00:04:05,490 --> 00:04:08,410
+sperm وضع انه عدد ال sperm zero فبالتالي
+
+55
+00:04:08,410 --> 00:04:12,530
+asospermia في تكنولوجيست اخر و emperiologist اخر
+
+56
+00:04:12,530 --> 00:04:16,840
+اكتر ضراية بالعملفأخد العينة ك total sample وضعها
+
+57
+00:04:16,840 --> 00:04:19,960
+في test tube وعملها centrifugation أخد جزء من ال
+
+58
+00:04:19,960 --> 00:04:24,800
+sediment وعملها scanning ماوجد sperm فبسميه
+
+59
+00:04:24,800 --> 00:04:29,060
+aspermia after centrifugation وهو المصطلح الأدق
+
+60
+00:04:29,060 --> 00:04:32,960
+لأن ممكن أنا لما أعمل mixing و أخد 50 micro أو 10
+
+61
+00:04:32,960 --> 00:04:35,780
+micro و أعملها scanning ومالاجيش لو أنا عملت
+
+62
+00:04:35,780 --> 00:04:39,020
+mixing كويس أو عملت centrifugation للعينة يعني
+
+63
+00:04:39,020 --> 00:04:42,650
+جمعتها ورصبتها وعملت لها concentrationواخدت من الـ
+
+64
+00:04:42,650 --> 00:04:45,650
+sediments ممكن ألاقي sperm او اتنين او تلاتة لأن
+
+65
+00:04:45,650 --> 00:04:50,130
+هذا بيأثر على طبيعة علاج المريض فيما بعد فمهم جدا
+
+66
+00:04:50,130 --> 00:04:54,070
+بعد ما ألاقي مصطلح Azospermia في العينة و أعمل فحص
+
+67
+00:04:54,070 --> 00:04:56,930
+للعينة و ألاقيها Azospermia أعملها centrifugation
+
+68
+00:04:56,930 --> 00:05:00,710
+و أفحصها مرة تانية عشان أقول Azospermia after
+
+69
+00:05:00,710 --> 00:05:04,030
+centrifugation أو لجت واحد sperm after
+
+70
+00:05:04,030 --> 00:05:08,150
+centrifugation فهذا المصطلح مهم جداهنتكلم عنه لما
+
+71
+00:05:08,150 --> 00:05:11,310
+نصل إلى الـ testicular biopsy كيف المصطلح
+
+72
+00:05:11,310 --> 00:05:15,570
+الازوسبيرميا after centrifugation بلعب دور كبير
+
+73
+00:05:15,570 --> 00:05:20,830
+ومهم في تحديد هل هذا الذكر أو هذا الرجل يلجأ إلى
+
+74
+00:05:20,830 --> 00:05:24,310
+ال testicular biopsy أو لا وإن لجأ إلى ال
+
+75
+00:05:24,310 --> 00:05:27,450
+testicular biopsy ما طبيعة ال biopsy هنتكلم في
+
+76
+00:05:27,450 --> 00:05:31,810
+عيندي أربع أنواع أسبابها بشكل أساسي أسباب
+
+77
+00:05:31,810 --> 00:05:35,150
+الازوسبيرميا قد تكون ال blockage على طول ال
+
+78
+00:05:35,150 --> 00:05:38,280
+reproductive tractأو قد يكون عندي abnormality في
+
+79
+00:05:38,280 --> 00:05:41,700
+ال hormone level وأشهرهم in FSH and H-testosterone
+
+80
+00:05:41,700 --> 00:05:45,040
+قد يكون عندي مشكلة في ال ejaculatory duct قد يكون
+
+81
+00:05:45,040 --> 00:05:48,820
+عندي مشكلة أساسية وظيفية أو تركيبية في ال
+
+82
+00:05:48,820 --> 00:05:52,580
+testicular وال testicular أو ال testis هي المصنع
+
+83
+00:05:52,580 --> 00:05:57,620
+الأساسي لإنتاج الاسبيرميا وبناء على هذا تم تقسيم
+
+84
+00:05:57,620 --> 00:06:01,880
+الاسبيرميا إلى قسمين أساسيين obstructive aspermia
+
+85
+00:06:01,880 --> 00:06:07,400
+و non-obstructive aspermiaفطالما تم تقسيم الـ
+
+86
+00:06:07,400 --> 00:06:09,700
+Azospermia إلى Obstructive وNon-obstructive
+
+87
+00:06:09,700 --> 00:06:13,720
+Azospermia ما هو الفرق؟ ما هو الفرق بين الـ
+
+88
+00:06:13,720 --> 00:06:17,020
+Obstructive وNon-obstructive Azospermia؟ الـ
+
+89
+00:06:17,020 --> 00:06:21,620
+Obstructive Azospermia وجدوا أن أكثر أسباب توجودها
+
+90
+00:06:21,620 --> 00:06:26,560
+هي عبارة عن Blockage في الـ Vase Difference أو الـ
+
+91
+00:06:26,560 --> 00:06:29,780
+Epidermis أو الـ Ejaculatory Duct فقط Blockage؟ لأ
+
+92
+00:06:30,010 --> 00:06:33,150
+واجهته ممكن يكون سبب آخر إن الـ Congenital Absence
+
+93
+00:06:33,150 --> 00:06:37,190
+في الـ Vast Difference إبداد مصر وإيجاكلوتريدارت
+
+94
+00:06:37,190 --> 00:06:39,650
+تبشوفوا الفرق بين ال blockage و الcongenital
+
+95
+00:06:39,650 --> 00:06:43,270
+absence ال blockage إن هذا علم الذكر أو هذا الرجل
+
+96
+00:06:43,270 --> 00:06:46,990
+تعرض إلى حادث معين عمل وجود blockage وانسداد في
+
+97
+00:06:46,990 --> 00:06:50,170
+هذه القنوات المذكورة التلاتة أما الcongenital
+
+98
+00:06:50,170 --> 00:06:55,290
+absence .. absence .. absence وهو إن ال male خُلِق
+
+99
+00:06:55,290 --> 00:07:00,610
+وولد وجاء على قيد الحياة وماعندهش هدىالمُركّبات أو
+
+100
+00:07:00,610 --> 00:07:03,510
+واحد منهم ماعندهوش الـ Epidermis ماعندهوش ال vast
+
+101
+00:07:03,510 --> 00:07:06,630
+difference وماعندهوش ال ejaculatory duct وارد صحيح
+
+102
+00:07:06,630 --> 00:07:11,390
+وارد ماهي المشاكل والأسباب التي تؤدي إلى حدوث ال
+
+103
+00:07:11,390 --> 00:07:13,990
+blockage بشكل أساسي لأن ال blockage يُعتبر هو
+
+104
+00:07:13,990 --> 00:07:18,350
+الأكثر انتشارة من أشهر الأسباب في عندي trauma أو
+
+105
+00:07:18,350 --> 00:07:21,810
+injury في منطقة .. في منطقة خاصة بال reproductive
+
+106
+00:07:21,810 --> 00:07:26,650
+tract infection أو inflammation في عندي عملية
+
+107
+00:07:26,650 --> 00:07:29,680
+جراحية في منطقة ال pelvic areaفي عندي الـ
+
+108
+00:07:29,680 --> 00:07:32,800
+vasectomy وهو إن الـ vas deference تعرض للاستقصال
+
+109
+00:07:32,800 --> 00:07:39,700
+ذكر رجل مصاب بـ cystic fibrosis أو mutation في
+
+110
+00:07:39,700 --> 00:07:43,040
+الجين الخاص بالـ cystic fibrosis فهذا الـ mutation
+
+111
+00:07:43,040 --> 00:07:47,600
+أدى إلى حدوث مشكلة في الـ vas deference مما أدى
+
+112
+00:07:47,600 --> 00:07:51,400
+إلى وجود مشكلة في تطور الـ vas deference فأدى إلى
+
+113
+00:07:51,400 --> 00:07:56,100
+حدوث blockage في الـ vas deference بشكل أساسي إذن،
+
+114
+00:07:56,100 --> 00:07:59,770
+بناء على هذا الكلامفي أسباب معينة علاقة بالـ
+
+115
+00:07:59,770 --> 00:08:05,770
+Obstructive Azospermia وتطرقنا إليها بشكل و بآخر و
+
+116
+00:08:05,770 --> 00:08:08,010
+من أشهر اللي قلنا عنها هي الـ Blockage في الـ
+
+117
+00:08:08,010 --> 00:08:11,270
+Vasodifference اللي بتدمس و النوع التاني الـ
+
+118
+00:08:11,270 --> 00:08:14,730
+Ejaculatory duct واحد منهم أو التلاتة مع بعضنجي
+
+119
+00:08:14,730 --> 00:08:18,990
+للشق الأخر من أنواع الـ Azospermia اللي حكيناها
+
+120
+00:08:18,990 --> 00:08:22,430
+Non-obstructive Azospermia والمعصود بالـ Non
+
+121
+00:08:22,430 --> 00:08:26,690
+-obstructive Azospermia أن التلاتة المُركّبات
+
+122
+00:08:26,690 --> 00:08:29,710
+الأساسية أو التركيبات التلاتة الأساسية سواء كان
+
+123
+00:08:29,710 --> 00:08:31,950
+الـ Epidermis أو الـBase Difference أو
+
+124
+00:08:31,950 --> 00:08:35,250
+الـGeriatric Reduct بيكونوا سالمين 100% ما في
+
+125
+00:08:35,250 --> 00:08:40,720
+عندهم Blockage ولكن في أسباب أخرى عبارة عنأسباب
+
+126
+00:08:40,720 --> 00:08:48,560
+جانبية أدت إلى إنقاس معدل إنتاج الـ sperm فبالتالي
+
+127
+00:08:48,560 --> 00:08:51,260
+هذه الـ external factor أو الـ other factor هي
+
+128
+00:08:51,260 --> 00:08:56,140
+اللي أثرت على المصنع بشكل أساسي ولم تؤثر على عوامل
+
+129
+00:08:56,140 --> 00:09:00,040
+أخرى خلّينا نشوف إيش ممكن الأسباب التي تؤدي إلى
+
+130
+00:09:00,040 --> 00:09:03,520
+الـ non-obstructive azospermia الـ non-obstructive
+
+131
+00:09:03,520 --> 00:09:07,760
+azospermia المقصود فيها أن التلت تركيباتالأساسية
+
+132
+00:09:07,760 --> 00:09:11,120
+اللي اتكلمنا عليها Vas deferens Epidermis جاكولاتي
+
+133
+00:09:11,120 --> 00:09:15,320
+ردكت Normal there is no blockage in this tipule or
+
+134
+00:09:15,320 --> 00:09:19,160
+in this tract ولكن there is another external
+
+135
+00:09:19,160 --> 00:09:23,140
+factor أثرت على الـ testis بشكل أساسي منها الـ
+
+136
+00:09:23,140 --> 00:09:29,800
+genetic causes أسباب ورثية من أشعر الـ Klinefelter
+
+137
+00:09:29,800 --> 00:09:33,620
+والـ Klinefelter هو عبارة عن male with two copies
+
+138
+00:09:33,620 --> 00:09:38,270
+of X chromosome فهذا يؤدي إلىوجود ضمور في الـ
+
+139
+00:09:38,270 --> 00:09:41,230
+testis مما يؤدي إلى إنقاس معدّى لإنتاج الـ spermia
+
+140
+00:09:41,230 --> 00:09:44,750
+أيضًا من أسباب الوراثية التي تؤدي إلى non
+
+141
+00:09:44,750 --> 00:09:47,030
+-obstructive azospermia أو بشكل أساسي الـ
+
+142
+00:09:47,030 --> 00:09:50,570
+azospermia ولكن non-obstructive هي وجود micro
+
+143
+00:09:50,570 --> 00:09:53,710
+-deletion في الـ Y-Chromosome لأن الـ Y-Chromosome
+
+144
+00:09:53,710 --> 00:09:58,750
+يحتوي على جينات تلعب دورة مهمة وأساسية وحساسة في
+
+145
+00:09:58,750 --> 00:10:02,820
+إنتاج الحيوانات المنويةفلو صار microdilation في
+
+146
+00:10:02,820 --> 00:10:06,000
+الـY كرمز وملاجينات أساسية معناه لـ production
+
+147
+00:10:06,000 --> 00:10:10,560
+rate will be declined هرمون abnormality or
+
+148
+00:10:10,560 --> 00:10:14,820
+imbalance ومن أشهر هذه الحالات وجود ما يُعرف اسمه
+
+149
+00:10:14,820 --> 00:10:18,940
+الـ Hypogonadotropic Hypogonadotropic يعني نقصان
+
+150
+00:10:18,940 --> 00:10:22,700
+في مستوى الهرمونات التي تفرز من مناطق معينة الجناد
+
+151
+00:10:22,700 --> 00:10:27,240
+ومن أشهر هذه الهرمونات التستيستيرون الذي يلعب دورة
+
+152
+00:10:27,240 --> 00:10:33,090
+مهمة في إنتاج وتطور ومدوجالحيوانات المنوية أيضًا
+
+153
+00:10:33,090 --> 00:10:38,130
+Hypogonadism من حيث الـGonadism أيضًا من أشهر
+
+154
+00:10:38,130 --> 00:10:44,830
+الأسباب أيضًا Hyperprolactinemia
+
+155
+00:10:44,830 --> 00:10:49,650
+بمعنى آخر زيادة مستوى هرمون البرولاكتين زي ما
+
+156
+00:10:49,650 --> 00:10:52,810
+البرولاكتين بيعمل infertility مؤقت عند الفيميل
+
+157
+00:10:52,810 --> 00:10:56,310
+أيضًا البرولاكتين قد يؤدي ويعمل بشكل سلبي على
+
+158
+00:10:56,310 --> 00:11:00,070
+المادة فبالتالي لازم للبرولاكتين يصير فيه عنده
+
+159
+00:11:00,690 --> 00:11:04,390
+عملية معالجة في حالة ارتفاعه من أسباب الهرمونية
+
+160
+00:11:04,390 --> 00:11:07,890
+أيضًا الـ Androgen-resistant أنه في عندي Androgen
+
+161
+00:11:07,890 --> 00:11:11,590
+-hormone وفي عندي Sex-hormone ولكن الـ Receptor مش
+
+162
+00:11:11,590 --> 00:11:15,230
+شغال عشان تستقبله فبالتالي لا يؤد الوظيفة المقلوبة
+
+163
+00:11:15,230 --> 00:11:19,650
+فيه سبب تاني من أسباب الـ Azoospermia ولكن الـ Non
+
+164
+00:11:19,650 --> 00:11:23,250
+-obstructive Azoospermia سيرتولي سيل Only Syndrome
+
+165
+00:11:23,250 --> 00:11:26,990
+وهي عبارة عن مشكلة في السيرتولي السيل التي تلعب
+
+166
+00:11:26,990 --> 00:11:31,540
+دورة مهمة في تطور وانضاجالحيوانات المنوية
+
+167
+00:11:31,540 --> 00:11:38,220
+spermatogenic arrest تستكل failure to produce full
+
+168
+00:11:38,220 --> 00:11:43,180
+mature sperm cell انه تستشغالة ولكن في عندها ضعف
+
+169
+00:11:43,180 --> 00:11:46,780
+في منطقة معينة أو في مرحلة معينة من مراحل التطور
+
+170
+00:11:46,780 --> 00:11:50,600
+ونضوج الحيوانات المنوية فبالتالي بيعطيني sperm
+
+171
+00:11:50,600 --> 00:11:55,600
+ولكن هذا ال sperm لا يكون ناضج بالشكل المطلوب أو
+
+172
+00:11:55,600 --> 00:12:01,400
+بالكيفية المطلوبةسبب آخر من أسباب الـ azoospermia
+
+173
+00:12:01,400 --> 00:12:05,640
+ولكن الـ non-obstructive ال trauma ال radiation ال
+
+174
+00:12:05,640 --> 00:12:09,760
+varicosein أيضا كيدنفيريا ال diabetes .. ال
+
+175
+00:12:09,760 --> 00:12:13,480
+diabetic أو ال diabetes ال cirrhosis هذه كلها
+
+176
+00:12:13,480 --> 00:12:18,300
+تعتبر من الأسباب التي تؤدي وتساهم في حدود ال non
+
+177
+00:12:18,300 --> 00:12:20,740
+-obstructive azoospermia ال non-obstructive
+
+178
+00:12:20,740 --> 00:12:25,260
+azoospermia في مصطلح تاني من المصطلحات الطبية
+
+179
+00:12:25,260 --> 00:12:31,460
+المهمةas in to zoospermia وهذا المصطلح مقصود فيه
+
+180
+00:12:31,460 --> 00:12:36,880
+أنه فيها عندي ك technologist عندي عينات عينات هذه
+
+181
+00:12:36,880 --> 00:12:41,220
+فيها sperm motility أو sperm motile ولكن في عندي
+
+182
+00:12:41,220 --> 00:12:45,900
+reduction في كمية ونسبة الحيوانات المنوية المتحركة
+
+183
+00:12:45,900 --> 00:12:51,260
+حتى تصل إلى أقل من 40% ورغم أنه ال normal range ل
+
+184
+00:12:51,260 --> 00:12:57,430
+ال total motile 42% عفوا 40%بس لـ Progressive 32%
+
+185
+00:12:57,430 --> 00:13:00,210
+فبالتالي لو صار في عندي reduction in the
+
+186
+00:13:00,210 --> 00:13:05,390
+percentage of total sperm motile less than 40% هذا
+
+187
+00:13:05,390 --> 00:13:09,870
+المصطلح بسميه سينو ذي سبيرميا طب شو أسبابه؟ شو
+
+188
+00:13:09,870 --> 00:13:13,670
+العوامل الممكن تسبب و تأثر على ال sperm motility؟
+
+189
+00:13:13,670 --> 00:13:17,290
+في عندي عدة عوامل من أول عوامل التي تؤثر سلبا عن
+
+190
+00:13:17,290 --> 00:13:21,670
+ال sperm motility ال Vercosyl دوال الخصية اخدوا
+
+191
+00:13:21,670 --> 00:13:25,290
+بالك ال Vercosyl هو عبارة عن تضخم في بعض الأوردةأو
+
+192
+00:13:25,290 --> 00:13:30,690
+التي تحيط بالـ testes تعتبر reversible بمعنى آخر
+
+193
+00:13:30,690 --> 00:13:35,910
+إنه ممكن يصير علاج إلها و ترجع مرة تانية هذا يعتبر
+
+194
+00:13:35,910 --> 00:13:39,930
+مشكلة مؤقتة تزال بعملية جراحية في عندي مشكلة أيضًا
+
+195
+00:13:39,930 --> 00:13:43,710
+seminal tract infection في عندي antisperm antibody
+
+196
+00:13:43,710 --> 00:13:47,190
+لأن الـ antibody هيعمل قتل للـ sperm ويفقد قدرته
+
+197
+00:13:47,190 --> 00:13:51,310
+على حركة فيما بيعمل reduction poor nutrition عندي
+
+198
+00:13:51,310 --> 00:13:54,380
+مشكلة في التخزينةما عنده كمية كافية من ال fractose
+
+199
+00:13:54,380 --> 00:13:58,400
+ما بتناول فواكه بكمية كافرة ما بتناول مصادر ال
+
+200
+00:13:58,400 --> 00:14:01,980
+fractose فبالتالي هيفقد ال sperm قدرته على الحركة
+
+201
+00:14:01,980 --> 00:14:07,460
+بسبب فقدانه العنصر الأساسي للحركة ال smoking ال
+
+202
+00:14:07,460 --> 00:14:10,280
+alcohol intake ال caffeine ال tobacco consumption
+
+203
+00:14:10,280 --> 00:14:17,020
+هذا كلها تعتبر من أسباب التي تؤدي إلى نقصان مستوى
+
+204
+00:14:17,020 --> 00:14:23,560
+ونسبة حركة الحيوانات المنوية هذه بشكل أساسيمن
+
+205
+00:14:23,560 --> 00:14:28,060
+الأسباب الأخرى التي تساهم في نقصان معدل ونسبة تحرك
+
+206
+00:14:28,060 --> 00:14:31,840
+الحيوانات المنوية هو التعرض لبعض الـ toxic agents
+
+207
+00:14:31,840 --> 00:14:36,740
+زي الناس الـ farmers الناس اللي بتشتغل في البنزينة
+
+208
+00:14:36,740 --> 00:14:38,960
+الناس اللي بتشتغل كمزارعين الناس اللي بتشتغل في
+
+209
+00:14:38,960 --> 00:14:43,120
+مصنع البطاريات الناس اللي بتشتغل في المناجم الفحم
+
+210
+00:14:43,120 --> 00:14:46,820
+تتعرض لكمية كبيرة جدا من ال organic solvent أو
+
+211
+00:14:46,820 --> 00:14:51,470
+المواد التي تعتبر مواد سامةالمشكلة ليست في التعرض،
+
+212
+00:14:51,470 --> 00:14:54,030
+المشكلة في كمية التعرض ووقت التعرض و ال
+
+213
+00:14:54,030 --> 00:14:56,350
+concentration اللي بتتعرض إليه الإنسان يعني ممكن
+
+214
+00:14:56,350 --> 00:14:59,250
+أي إنس إحنا في حياتنا اليوم دي متتعرض ولكن جنتيش
+
+215
+00:14:59,250 --> 00:15:01,910
+متتعرض، أنت ممكن تتعرض ساعة، من إزاي اللي بيشتغل
+
+216
+00:15:01,910 --> 00:15:04,870
+في البنزينة بدوام 12 ساعة؟ ومش اللي بيشتغل في
+
+217
+00:15:04,870 --> 00:15:09,110
+الفحم و في منجم الفحم بدوام ممكن يصل إلى 24 ساعة،
+
+218
+00:15:09,110 --> 00:15:12,710
+متواصل أو متقطع فبالتالي في عنده duration لل
+
+219
+00:15:12,710 --> 00:15:18,750
+exposure كمية، توقت عالي جدا، فبيعمل مشاكل في ال
+
+220
+00:15:18,750 --> 00:15:22,970
+spare motilityأيضًا الـ Age بيلعب دور عكسي في
+
+221
+00:15:22,970 --> 00:15:29,390
+وجهية الدراسات أن هناك علاقة سلبية ما بين الـ Age
+
+222
+00:15:29,390 --> 00:15:34,870
+و percentage of sperm motility تحت مصطلح Negative
+
+223
+00:15:34,870 --> 00:15:37,690
+Correlation between the Male Age and the
+
+224
+00:15:37,690 --> 00:15:41,130
+Percentage of Sperm Motile كل ما زاد ال Age قل
+
+225
+00:15:41,130 --> 00:15:44,510
+الموتلتي كل ما قل ال Age زاد الموتالي ال sperm
+
+226
+00:15:44,510 --> 00:15:48,170
+أيضًا ال Cancer بيلعب دور سلبي لأنه طول ما في عندي
+
+227
+00:15:48,170 --> 00:15:50,540
+Cancerفي عند الـ Radiotherapy، في عند الـ
+
+228
+00:15:50,540 --> 00:15:55,000
+Chemotherapy وكلهم يؤثر سلبًا على مصنع الحيوانات
+
+229
+00:15:55,000 --> 00:15:57,980
+المنوية وفيأثر سلبًا على الحيوانات المنوية
+
+230
+00:15:57,980 --> 00:16:00,600
+الموجودة في الـ edited mass ويؤثر سلبًا على
+
+231
+00:16:00,600 --> 00:16:04,740
+الحيوانات المنوية التي ما زالت تُخلق فبالتالي، دي
+
+232
+00:16:04,740 --> 00:16:09,180
+بيعمل reduction عندى في عدد ال sperm المتحارب في
+
+233
+00:16:09,180 --> 00:16:13,540
+عنده مصطلح آخر اسمه Teratospermia ما المقصود بهذا
+
+234
+00:16:13,540 --> 00:16:18,320
+المصطلح Teratospermia معناه إن في أنا عند spermفي
+
+235
+00:16:18,320 --> 00:16:22,980
+عندى spermatozoa وفي عندى mature sperm ولكن معدل
+
+236
+00:16:22,980 --> 00:16:28,560
+ال .. او نسبة .. نسبة ال sperm اللى يعتبر up
+
+237
+00:16:28,560 --> 00:16:32,360
+normal form عالى جدا up normal form يعني ميجارو
+
+238
+00:16:32,360 --> 00:16:36,060
+head، pen head، double tail، two mid piece يعني
+
+239
+00:16:36,060 --> 00:16:40,440
+بمعنى اخر انا عملت scanning للعينة لجيت عدد ومستوى
+
+240
+00:16:40,440 --> 00:16:44,240
+ونسبة ومعدل تواجد ال up normal form spermatozoa
+
+241
+00:16:44,240 --> 00:16:49,850
+عالى جدابالتالي بسميها Teratospermia Teratospermia
+
+242
+00:16:49,850 --> 00:16:53,530
+شو أسبابها؟ شو ال most common؟ شو الفكرة التي تؤدي
+
+243
+00:16:53,530 --> 00:16:58,010
+إلى حدوث Teratospermia؟ أول حاجة ال infection ال
+
+244
+00:16:58,010 --> 00:17:01,650
+chronic infection كل ما اتعرضت أو حنعرف إيش عن ال
+
+245
+00:17:01,650 --> 00:17:05,250
+chronic infection أو كيف ال chronic infection بسبب
+
+246
+00:17:05,250 --> 00:17:09,790
+تغيب في أشكال الحيوانات خدوا بالكوا أربطوها و
+
+247
+00:17:09,790 --> 00:17:12,770
+هنتكلم عنها بشكل مستفيد تكلمنا عن المحاضرة الفاتتة
+
+248
+00:17:13,100 --> 00:17:15,660
+Coronic infection يعني ال immune system هيشتغل
+
+249
+00:17:15,660 --> 00:17:19,560
+يعني في عندي white pieces هتهاجل للمنطقة هذه هتفرز
+
+250
+00:17:19,560 --> 00:17:22,720
+ال white pieces كمية كبيرة جدا من ال free radical
+
+251
+00:17:22,720 --> 00:17:27,380
+فتديني ROS Reactive Oxygen Species هذي بتعملي
+
+252
+00:17:27,380 --> 00:17:30,780
+degradation في ال DNA و في المorphology بتاعة ال
+
+253
+00:17:30,780 --> 00:17:35,040
+sperm ببساطة جدا Smoking و ال alcohol intake تؤدي
+
+254
+00:17:35,040 --> 00:17:39,600
+إلى Teratospermia عدم وجود اتزان و تناور طعام صحي
+
+255
+00:17:39,600 --> 00:17:43,250
+تؤدي إلى Teratospermiaالـ Obesity تعتبر من أهم
+
+256
+00:17:43,250 --> 00:17:46,730
+العوامل التي تساعد في وجود Teratospermia الـ Drug
+
+257
+00:17:46,730 --> 00:17:51,830
+الذي يتم تناوله بغير وصفة طبية أو بغير جرعة طبية
+
+258
+00:17:51,830 --> 00:17:55,210
+بعض الأدوية تؤثر سلبة أيضًا وجود ال trauma في
+
+259
+00:17:55,210 --> 00:17:59,610
+منطقة ال testicular تؤثر على ال morphology الخاص
+
+260
+00:17:59,610 --> 00:18:04,870
+بالـ spermatozoa كل هذه المصطلحات وكل هذه الأسباب
+
+261
+00:18:04,870 --> 00:18:09,990
+تؤدي إلى حدوث مشاكل في عملية إنتاجأو تطور أو مدوج
+
+262
+00:18:09,990 --> 00:18:14,730
+الـ spermatozoa مصطلح آخر بنسميه polyospermia
+
+263
+00:18:14,730 --> 00:18:20,710
+polyospermia وهو عبارة عن مصطلح المقصود فيه زيادة
+
+264
+00:18:20,710 --> 00:18:25,490
+عدد الحيوانات المنوية في السائل لتصل إلى أكثر من
+
+265
+00:18:25,490 --> 00:18:29,850
+200 مليون خلية أو 200 مليون sperm per milliliter
+
+266
+00:18:29,850 --> 00:18:34,450
+increase in the total number of spermatozoa to
+
+267
+00:18:34,450 --> 00:18:39,550
+arrive 200 million per milliliterطبعا هذا العدد
+
+268
+00:18:39,550 --> 00:18:43,670
+مهول يعتبر ومش كل زيادة في العدد تعتبر زيادة
+
+269
+00:18:43,670 --> 00:18:48,170
+إيجابية فبالتالي الزيادة قد تكون سلبية ببساطة جدا
+
+270
+00:18:48,170 --> 00:18:51,870
+تصور أن أنت عندك كمية كبيرة جدا قد كل المدرسة أو
+
+271
+00:18:51,870 --> 00:18:56,130
+كل الجامعة في حالة من حالات التصقيد سوف تخرج من
+
+272
+00:18:56,130 --> 00:19:00,730
+بوابة صغيرة جدا سوف يحدث تدافع عند عملية الخروج
+
+273
+00:19:00,730 --> 00:19:05,970
+مما يؤدي إلى وجود إصابات وقد يؤدي إلى اختناقات على
+
+274
+00:19:05,970 --> 00:19:10,640
+صعيد بسيط جداعلى الوضع الحالي فمباناك لو كان عندك
+
+275
+00:19:10,640 --> 00:19:17,340
+200 مليون sperm هيخرجوه بشكل دفقات متتالية هيصير
+
+276
+00:19:17,340 --> 00:19:21,240
+في اندي نوع من أنواع إعاقة في الحركة إعاقة في
+
+277
+00:19:21,240 --> 00:19:26,340
+الحركة يعني تدمير يعني ال fertility chance حدجه و
+
+278
+00:19:26,340 --> 00:19:30,420
+حدجيه عند المال طبعا it is usually associated with
+
+279
+00:19:30,420 --> 00:19:33,940
+a decrease in the volume of ejaculatory matter هذا
+
+280
+00:19:33,940 --> 00:19:37,390
+السبب اللي بيؤدي إلى زيادة الحجز زيادة العددإن ال
+
+281
+00:19:37,390 --> 00:19:40,210
+volume بدل ما يكون خمسة فيهم 200 مليون كان فيها
+
+282
+00:19:40,210 --> 00:19:45,090
+واحد مل فيهم 200 مليون فمن أهم أسباب زيادة ال
+
+283
+00:19:45,090 --> 00:19:49,330
+concentration of sperm أو دعنا نسميها زيادة ال
+
+284
+00:19:49,330 --> 00:19:52,330
+count of sperm هو عبارة عن حدوث reduction في ال
+
+285
+00:19:52,330 --> 00:19:55,730
+sperm volume في ال seminal volume it may be a
+
+286
+00:19:55,730 --> 00:19:59,610
+cause of infertility since such high concentration
+
+287
+00:19:59,610 --> 00:20:03,250
+can be difficult to their movement طبعا زيادة في
+
+288
+00:20:03,250 --> 00:20:08,670
+العدديودى الى تزاحم أثناء المسير في رحلة ال
+
+289
+00:20:08,670 --> 00:20:13,450
+fertilization فالتزاحم هذا هيكون تزاحم عكسى فهيمنع
+
+290
+00:20:13,450 --> 00:20:17,030
+من حركة ال despair ما تزوى بشكل المطلوب و بشكل
+
+291
+00:20:17,030 --> 00:20:22,970
+المناسب لأن فيه تدافع طبعا it is important
+
+292
+00:20:22,970 --> 00:20:26,710
+condition in male fertility because white cell
+
+293
+00:20:26,710 --> 00:20:30,790
+weak in the sperm and can't damage its genetic
+
+294
+00:20:30,790 --> 00:20:38,690
+material طبعا أيضا من أهم المصطلحاتوجود بعض ال
+
+295
+00:20:38,690 --> 00:20:43,790
+white pieces تؤثر سلبًا على هذه العملية طبعًا وجود
+
+296
+00:20:43,790 --> 00:20:47,970
+ال white pieces لها علاقة بحاجة بتسميها
+
+297
+00:20:47,970 --> 00:20:52,250
+Pyrospermia أو حاجة بتسميها present of leukocyte
+
+298
+00:20:52,250 --> 00:20:56,230
+in seminal fluid طبعًا وجود ال leukocyte في ال
+
+299
+00:20:56,230 --> 00:21:00,190
+seminal fluid معناه أنه في عندى infection ال
+
+300
+00:21:00,190 --> 00:21:03,230
+infection هيهاجر كمية كبيرة جدًا من ال white
+
+301
+00:21:03,230 --> 00:21:05,470
+pieces لدى المكان فبالتالي هيعملها destruction
+
+302
+00:21:06,450 --> 00:21:10,990
+ببساطة جدا وجود ال white pieces هيعمل رُس رُس
+
+303
+00:21:10,990 --> 00:21:15,870
+هيعمل destruction لgenetic material فيؤدي إلى فشل
+
+304
+00:21:15,870 --> 00:21:21,870
+ال sperm في قدرته على عملية الإخصاب while the
+
+305
+00:21:21,870 --> 00:21:24,170
+blood cell released powerful substance called
+
+306
+00:21:24,170 --> 00:21:27,430
+reactive oxygen species which destroy organism
+
+307
+00:21:27,430 --> 00:21:32,650
+that cause infection unfortunately أو للأسف بشكل
+
+308
+00:21:32,650 --> 00:21:38,540
+كبير جداوجدوا إن الرُس بتأثر سلبًا بشكل كبير جدًا
+
+309
+00:21:38,540 --> 00:21:42,260
+على الـ sperm DNA على الـ sperm motility وعلى الـ
+
+310
+00:21:42,260 --> 00:21:45,280
+sperm movement طبعًا فادوا بالكواخر تلت نقاط اللي
+
+311
+00:21:45,280 --> 00:21:49,540
+لهم علاقة بمصطلح وجود حاجة بنتسميها leukospermia
+
+312
+00:21:49,540 --> 00:21:53,260
+وليكوسبيرميا بيسموها وجود الـ leukocyte بكميات
+
+313
+00:21:53,260 --> 00:21:57,740
+كبيرة جدًا في الـ seminal fluid هذه رقم تلاتة
+
+314
+00:21:57,740 --> 00:22:01,560
+النقطة رقم تلاتة ونقطة رقم أربع ونقطة رقم خامسة
+
+315
+00:22:01,560 --> 00:22:05,140
+إلها علاقة بمصطلح اسمه leukospermia أو Pyrospermia
+
+316
+00:22:05,660 --> 00:22:08,740
+وهذا المصطلح Leukospermia أو Pyrospermia هي عبارة
+
+317
+00:22:08,740 --> 00:22:12,240
+عن present of leukocyte in seminal fluid with high
+
+318
+00:22:12,240 --> 00:22:19,120
+number طبعا هذه المفروض في هنا عنوان جديد خلصنا من
+
+319
+00:22:19,120 --> 00:22:23,120
+المصطلحات التطبيقية المهمة سننتقل إلى موضوع جديد
+
+320
+00:22:23,120 --> 00:22:28,780
+كيف يتم تحضير عينات السائل من أجل ال ART أو ال X
+
+321
+00:22:28,780 --> 00:22:36,070
+أحد تقنيات ال ART طبعا في البداية في عندي مصطلحالـ
+
+322
+00:22:36,070 --> 00:22:39,630
+IVF In Vitro Fertilization فيها عند مصطلح الـ IGSI
+
+323
+00:22:39,630 --> 00:22:43,550
+وفيها عند مصطلح ال IUI إيش يعني ال IUI اختصارها
+
+324
+00:22:43,550 --> 00:22:49,650
+Intrauterine Insemination وهي ببساطة جدا هي إيصال
+
+325
+00:22:49,650 --> 00:22:56,510
+لـ spermatozoa الناضجة إلى الرحم
+
+326
+00:22:56,510 --> 00:23:03,930
+متى بنستخدمها إذا كان في مواجهة عنيفةمن قبل الـ
+
+327
+00:23:03,930 --> 00:23:06,970
+Female Piers الموجودة في منطقة الـ cervic ومنطقة
+
+328
+00:23:06,970 --> 00:23:11,130
+الفيجاينة لـ spermatozoa أو ال spermatozoa لا تقدر
+
+329
+00:23:11,130 --> 00:23:15,010
+تقطع هذه المسافة فبيجي الطبيب بياخد ال spermatozoa
+
+330
+00:23:15,010 --> 00:23:17,550
+بيعملها preparation بيحطها في انبوبة اسمها
+
+331
+00:23:17,550 --> 00:23:21,270
+catheter tube very thin و بيحطنها داخل الفاجاينة
+
+332
+00:23:21,270 --> 00:23:24,890
+الخاصة بالفيميل أو ببعناء آخر داخل الرحم الخاص
+
+333
+00:23:24,890 --> 00:23:28,690
+بالفيميل مرورا بالفاجاينة و السيرفيكال فبيقصر
+
+334
+00:23:28,690 --> 00:23:33,240
+المسافة اللي هتمشيها ال spermatozoa و بيقصروبيقلل
+
+335
+00:23:33,240 --> 00:23:35,980
+معدل الأخطار اللي بتوجهها الـ spermatozoa هذا
+
+336
+00:23:35,980 --> 00:23:41,100
+المصطلح بنسميه IUI intrauterine insemination يعني
+
+337
+00:23:41,100 --> 00:23:45,780
+الحقن داخل الرحم طبعا هذه بنعملها إذا كان الفيمايل
+
+338
+00:23:45,780 --> 00:23:49,580
+قبيعية 100% ولكن في عندى مشكلة في ال motility
+
+339
+00:23:49,580 --> 00:23:56,360
+الخاصة بال male spermatozoa شو السبب منها؟ شو
+
+340
+00:23:56,360 --> 00:24:00,700
+الهدف منها؟ تقليلالمصاعب والمخاطر اللي يتواجهها
+
+341
+00:24:00,700 --> 00:24:05,340
+الـ spermatozoa خلال رحلة ال fertilization في
+
+342
+00:24:05,340 --> 00:24:08,700
+منطقة ال cervical أو منطقة الفاجينة مرتبطة على الـ
+
+343
+00:24:08,700 --> 00:24:14,920
+leukocyte و الـ antisperm antibody و خلافه طيب ال
+
+344
+00:24:14,920 --> 00:24:20,440
+sperm process for IVF كيف يتم تحضير العينة؟ أو
+
+345
+00:24:20,440 --> 00:24:24,210
+خلال عملية تحضير العينة، شو بيصير؟طبعا خلال .. أو
+
+346
+00:24:24,210 --> 00:24:27,250
+فكرة تحضير العينة و الفكرة الأساسية للتحضير العينة
+
+347
+00:24:27,250 --> 00:24:31,010
+ومبدأ تحضير العينة يقوم على مبدأ أساسي هو عزل
+
+348
+00:24:31,010 --> 00:24:35,370
+الحيوانات المنوية الجيدة التي تعتبر normal form و
+
+349
+00:24:35,370 --> 00:24:38,690
+good motile فبالتالي طالما في عندي عزل للحيوانات
+
+350
+00:24:38,690 --> 00:24:42,130
+المنوية الجيدة إذا سوف يتم التخلص من ال similar
+
+351
+00:24:42,130 --> 00:24:47,830
+fluid أو ال similar plasma يتم التخلص من خلالها من
+
+352
+00:24:47,830 --> 00:24:50,790
+العوامل التي تعمل decapacitation والمقصود بال
+
+353
+00:24:50,790 --> 00:24:53,880
+decapacitationيعني فقدان الحيوانة المنوية القدرة
+
+354
+00:24:53,880 --> 00:24:59,920
+على الإخصاب إبعاد وعزل الـ dysfunctional والرُس
+
+355
+00:24:59,920 --> 00:25:05,680
+producing sperm بمعنى آخر إبعاد الـ sperm بـ
+
+356
+00:25:05,680 --> 00:25:09,340
+dysfunction اللي ممكن يفرس كمية كبيرة جدا من الرُس
+
+357
+00:25:09,340 --> 00:25:13,460
+اللي بتدمر الحيوانات المنوية الأخرى التخلص من الـ
+
+358
+00:25:13,460 --> 00:25:16,980
+leukocyte لأن الـ leukocyte جالب شوية حكينا ممكن
+
+359
+00:25:16,980 --> 00:25:22,580
+تفرس كمية كبيرة جدا من الرُس التخلص من البكتيريامن
+
+360
+00:25:22,580 --> 00:25:26,720
+أن البكتيريا تلعب سلبًا ودورًا سلبيًا على
+
+361
+00:25:26,720 --> 00:25:31,940
+الحيوانات المنوية المتبقية وتحسين قدرة الـ sperm
+
+362
+00:25:31,940 --> 00:25:36,000
+من حيث الحركة والمحافظة على المادة الوراثية بالشكل
+
+363
+00:25:36,000 --> 00:25:39,040
+الكامل بالإضافة إلى المحافظة على الـ Acrosome
+
+364
+00:25:39,040 --> 00:25:41,780
+Reaction والمحافظة على الـ sperm في حالة Normal
+
+365
+00:25:41,780 --> 00:25:47,580
+Form إذن هذه الخمس نقاط، خمس نقاط أساسية تحدث خلال
+
+366
+00:25:47,580 --> 00:25:51,720
+عملية الـ Sperm Processing for IVF-CorIgZ من أجلها
+
+367
+00:25:51,920 --> 00:25:54,900
+يتم المحافظة على الـ sperm يتم المحافظة على الـ
+
+368
+00:25:54,900 --> 00:25:57,780
+sperm و الـ acrosome .. sperm morphology و الـ
+
+369
+00:25:57,780 --> 00:26:01,580
+acrosome reaction و الـ motility الخاصة بالـ sperm
+
+370
+00:26:01,580 --> 00:26:05,580
+كيف يتم المحافظة على هذه الأمور؟ من خلال التخلص من
+
+371
+00:26:05,580 --> 00:26:08,520
+الحيوانات المنوية الميتة التخلص من البكتيريا
+
+372
+00:26:08,520 --> 00:26:12,100
+التخلص من الكورات الدم البيضاء و التخلص من الـ
+
+373
+00:26:12,100 --> 00:26:15,600
+seminal plasma التي قد تحتوي على الـ ant sperm
+
+374
+00:26:15,600 --> 00:26:20,200
+antibody أو إذا كان طبعاً للملاي يصنع antibody ضد
+
+375
+00:26:20,200 --> 00:26:25,070
+نفسهأو يحتوي على الـ Decapitation Factor هذه أهم
+
+376
+00:26:25,070 --> 00:26:30,750
+خمسة نقاط أساسية أهم خمسة نقاط أساسية ما هي الطرق
+
+377
+00:26:30,750 --> 00:26:34,130
+التي تستخدم في عملية ال isolation أول طريقة تستخدم
+
+378
+00:26:34,130 --> 00:26:36,750
+في عملية ال isolation و ال extraction و ال
+
+379
+00:26:36,750 --> 00:26:41,770
+processing هي طريقة بسيطة جدا تسمى simple dilution
+
+380
+00:26:41,770 --> 00:26:45,190
+and washing simple dilution and washing هنتكلم
+
+381
+00:26:45,190 --> 00:26:48,490
+عنها بالتفصيل النقطة التانية أو الطريقة التانية هي
+
+382
+00:26:48,490 --> 00:26:53,710
+ال swarm up و من اسمهاسباحة للأعلى النقطة التالتة
+
+383
+00:26:53,710 --> 00:26:57,510
+و الطريقة التالتة هي density أو density gradient
+
+384
+00:26:57,510 --> 00:27:01,510
+centrifugation density gradient gradient
+
+385
+00:27:01,510 --> 00:27:06,870
+centrifugation بمعنى آخر الفصل بناء على الكثافة
+
+386
+00:27:06,870 --> 00:27:11,270
+المتدرجة في عندي simple dilution and washing في
+
+387
+00:27:11,270 --> 00:27:14,650
+عندي sperm swarm up في عندي density gradient
+
+388
+00:27:14,650 --> 00:27:18,420
+centrifugationطبعا هذه التلت نقاط أو التلت عوامل
+
+389
+00:27:18,420 --> 00:27:22,960
+أو التلت طرق ان صح التعبير الأكثر استخداما والأكثر
+
+390
+00:27:22,960 --> 00:27:27,080
+شيوعا ولكن حاليا الأكثر استخداما الطريقة التانية
+
+391
+00:27:27,080 --> 00:27:30,960
+أو التالتة والأكثر على الإطلاق والأكثر استخداما في
+
+392
+00:27:30,960 --> 00:27:34,060
+مختبرات ال IWF هي الطريقة التالتة اللي لها علاقة
+
+393
+00:27:34,060 --> 00:27:37,700
+بال credit خلينا ناخد الطريقة الأولى اللي اسمها
+
+394
+00:27:37,700 --> 00:27:42,010
+simple dilution and washingببساطة جدًا خلال هذه
+
+395
+00:27:42,010 --> 00:27:45,550
+العملية يتم فصل الـ spermatozoa عن الـ seminal
+
+396
+00:27:45,550 --> 00:27:49,810
+fluid بما يحتويه فصل ال spermatozoa عن ال seminal
+
+397
+00:27:49,810 --> 00:27:55,130
+fluid بما يحتويه هذا البرنامج يحفظ قدرة البرنامج
+
+398
+00:27:55,130 --> 00:27:58,910
+للتواصل بشكل كبير بما يحتوي على البرنامج بما يحتوي
+
+399
+00:27:58,910 --> 00:28:01,110
+على البرنامج بما يحتوي على البرنامج بما يحتوي على
+
+400
+00:28:01,110 --> 00:28:02,530
+البرنامج بما يحتوي على البرنامج بما يحتوي على
+
+401
+00:28:02,530 --> 00:28:05,310
+البرنامج بما يحتوي على البرنامج بما يحتوي على
+
+402
+00:28:05,310 --> 00:28:06,170
+البرنامج بما يحتوي على البرنامج بما يحتوي على
+
+403
+00:28:06,170 --> 00:28:08,210
+البرنامج بما يحتوي على البرنامج بما يحتوي على
+
+404
+00:28:08,210 --> 00:28:11,770
+البرنامج بما يحتوي على الهذه الطريقة الأولى، يعني
+
+405
+00:28:11,770 --> 00:28:16,430
+أكثر .. أو أكثر الحالات التي يستخدم معها الطريقة
+
+406
+00:28:16,430 --> 00:28:19,050
+الأولى الـ simple dilution and washing مثل .. إذا
+
+407
+00:28:19,050 --> 00:28:23,570
+كان في عندي immune disorder إذا كان في عندي male
+
+408
+00:28:23,570 --> 00:28:30,590
+factor أو حالات عدم إنجاب غير معروفة السبب طبعا
+
+409
+00:28:30,590 --> 00:28:33,070
+هذا ال .. هذا ال technique بيحتاج dilution و
+
+410
+00:28:33,070 --> 00:28:37,270
+centrifugation طبعا ال sperm بيصير له washing ب
+
+411
+00:28:37,270 --> 00:28:40,370
+solution يحتوي على ال antibioticوبعض الـ
+
+412
+00:28:40,370 --> 00:28:44,390
+Supplemental Protein ومن أشهرهم الـ albumin يُضاف
+
+413
+00:28:44,390 --> 00:28:47,530
+يعني كإن أنا بستخدم media هذه ال media فيها
+
+414
+00:28:47,530 --> 00:28:52,210
+Antibiotic plus Supplemental Protein like albumin
+
+415
+00:28:52,210 --> 00:28:56,890
+بضيفها على عينة السمن بمعدل 1 إلى 1، 2 إلى 2
+
+416
+00:28:56,890 --> 00:29:00,350
+وخلافه ولكن الأكثر استخدام من ال ratio one to one
+
+417
+00:29:00,350 --> 00:29:05,590
+ال media sterile of the equal volume from the
+
+418
+00:29:05,590 --> 00:29:07,970
+seminal fluid يعني ال ratio ما بين ال media
+
+419
+00:29:07,970 --> 00:29:10,930
+المستخدمةالتي تحتوى على الـ Supplement Protein و
+
+420
+00:29:10,930 --> 00:29:15,330
+الـ Antibiotic إلى كمية السمن الفلويد لازم تكون 1
+
+421
+00:29:15,330 --> 00:29:19,690
+ل 1 بمعنى انا اضفت او بدي اعمل Washing ل 1ml من
+
+422
+00:29:19,690 --> 00:29:23,590
+العينة بدي اضيف 1ml من الـ Sample فباتشي بعمل
+
+423
+00:29:23,590 --> 00:29:26,770
+Mixing للعينة و بقيس كده عندى ال volume تدريجى
+
+424
+00:29:26,770 --> 00:29:30,400
+عندى 5mlإذا لازم أضيف عليهم خمسة mil من ال media
+
+425
+00:29:30,400 --> 00:29:34,220
+بعملها good mixing بعدين بضيفها في test tube و
+
+426
+00:29:34,220 --> 00:29:38,140
+بعملها centrifugation ع باستخدام طبعا ال
+
+427
+00:29:38,140 --> 00:29:42,300
+centrifuge طبعا ال centrifugation لها زمن معين و
+
+428
+00:29:42,300 --> 00:29:46,760
+سرعة معينة فبعملها centrifugation على تلاتمية دورة
+
+429
+00:29:46,760 --> 00:29:52,840
+300G لمدة عشر دقائق فهتفصلن مركبين أو طبقتين ال
+
+430
+00:29:52,840 --> 00:29:55,560
+cinnamon في الأسفل و ال supernatant كلها في الأعلى
+
+431
+00:29:56,430 --> 00:30:00,630
+removing with sterile pipet طبعا هنا for 10 minute
+
+432
+00:30:00,630 --> 00:30:04,310
+and then the supernatant is very careful remove
+
+433
+00:30:04,310 --> 00:30:08,630
+طبعا ال supernatant أنا مابديه لإنه فيه كل ال
+
+434
+00:30:08,630 --> 00:30:12,410
+depressed فيه كل ال decomposition factor فيه كل
+
+435
+00:30:12,410 --> 00:30:17,010
+العوامل اللي ممكن تأثر سلبا على ال sperm فبعمل
+
+436
+00:30:17,010 --> 00:30:21,530
+removing لل supernatant بسحبه بال sterile pipet او
+
+437
+00:30:21,530 --> 00:30:25,030
+ال dropper و برميهالـ Palette أو الـ Sediment
+
+438
+00:30:25,030 --> 00:30:28,230
+الموجود بعملها Resuspension و بضيف عليها بعد كده
+
+439
+00:30:28,230 --> 00:30:31,610
+واحد ملي من نفس ال media و بعملها Mixing و
+
+440
+00:30:31,610 --> 00:30:35,810
+Centrifugation لمدة خمس دقائق على نفس السرعة 300G
+
+441
+00:30:35,810 --> 00:30:39,110
+برفع ال supernatant و برميه بتخلص منه و بعمله
+
+442
+00:30:39,110 --> 00:30:42,910
+discard بعد كده بعمل Resuspension لل Palette و
+
+443
+00:30:42,910 --> 00:30:46,010
+بضيف عليها واحد مل من نفس ال media أنا كده بكون
+
+444
+00:30:46,010 --> 00:30:49,410
+غسلتها مرتين ممكن أغسلها كمان مرة مافيش مشكلة بضيف
+
+445
+00:30:49,410 --> 00:30:53,140
+واحد مل مرة تانيةmixing centrifugation على 300G
+
+446
+00:30:53,140 --> 00:30:57,580
+لمدة خمس دقائق بتخلص من ال super net and بضيف او
+
+447
+00:30:57,580 --> 00:31:01,780
+بعمل resuspension لل sediment الموجود او للبلد
+
+448
+00:31:01,780 --> 00:31:09,060
+الموجود طبعا كده ال sediment بتكون جاهزة لعملية ال
+
+449
+00:31:09,060 --> 00:31:13,360
+IUI for example جاهزة لعملية ال IVF for example
+
+450
+00:31:13,360 --> 00:31:16,620
+بناء على طبيعة العينة او طبيعة ال process اللي انا
+
+451
+00:31:16,620 --> 00:31:19,990
+بدي استخدامهطبعا استخدمت عشر دقائق و بعدين عشر
+
+452
+00:31:19,990 --> 00:31:22,630
+دقائق و بعدين عشر دقائق يعني ممكن تاخد ل minimum
+
+453
+00:31:22,630 --> 00:31:27,110
+تلاتين دقيقة العملية ككل ما بين عملية ال first
+
+454
+00:31:27,110 --> 00:31:33,150
+centrifugation حتى ال last time أو ال last step
+
+455
+00:31:33,150 --> 00:31:37,630
+centrifugation طبعا مهم جدا جابل ما أكون جهزت
+
+456
+00:31:37,630 --> 00:31:43,090
+العينة و بعدتها ل ال empirical lab أو لعملية الحقن
+
+457
+00:31:43,090 --> 00:31:47,420
+بشكل أساسي لازم أعمل evaluationللعينة او للبلد او
+
+458
+00:31:47,420 --> 00:31:50,560
+لل cinnamon ان اشوف ماجدش فيه متايل sperm ماجدش
+
+459
+00:31:50,560 --> 00:31:54,420
+فيه count sperm بعد كده اعملها preparation
+
+460
+00:31:54,420 --> 00:31:58,480
+preparing for insemination insemination يعني الحقن
+
+461
+00:31:58,480 --> 00:32:02,900
+الحقن اي ماقصود فيه برجع بأكد ان هذه العملية بتاخد
+
+462
+00:32:02,900 --> 00:32:06,680
+لها كمية قليلة جدا من الوقت يعني تلاتين الاربعين
+
+463
+00:32:06,680 --> 00:32:10,960
+دقيقة يعني مش الوقت الكبير المرحلة التانية من
+
+464
+00:32:10,960 --> 00:32:13,720
+المرحلة التي تستخدم او الطريقة التانية طريقة ال
+
+465
+00:32:13,720 --> 00:32:16,400
+swarm upطبعاً طريقة this warm-up هي أكثر الطرق
+
+466
+00:32:16,400 --> 00:32:18,660
+التي يتم فيها استخدامها في ال research على سبيل
+
+467
+00:32:18,660 --> 00:32:22,500
+المثال و ال I.O.I. ال research و ال I.O.I. طبعاً
+
+468
+00:32:22,500 --> 00:32:25,240
+في هذه العملية أو عملية this warm-up ال principle
+
+469
+00:32:25,240 --> 00:32:29,140
+أساسي الخاص فيها أنه فقط ال spermatozoa التي
+
+470
+00:32:29,140 --> 00:32:32,940
+بتعتبر pest motility أو pest motile .. pest motile
+
+471
+00:32:32,940 --> 00:32:36,880
+spermatozoa هي التي تستطيع السباحة للأعلى يعني هنا
+
+472
+00:32:36,880 --> 00:32:41,180
+بفصل فقط ال motile sperm عن باقي ال spermatozoa عن
+
+473
+00:32:41,180 --> 00:32:45,170
+باقي ال depressedعن باقي الأمور التي لا نريد أن
+
+474
+00:32:45,170 --> 00:32:50,450
+تتواجد مع العينة ليه؟ لأن ببساطة جدا الحيوانات
+
+475
+00:32:50,450 --> 00:32:54,750
+المنوية الأكثر صحة الأكثر قدرة على الحركة التي
+
+476
+00:32:54,750 --> 00:32:57,950
+تعتبر حركتها طبيعية هي التي تستطيع أن تسبح للأعلى
+
+477
+00:32:57,950 --> 00:33:03,170
+طب ليه تسبح للأعلى؟ هنعرف ليه سميت أصلا سواقة طبعا
+
+478
+00:33:03,170 --> 00:33:06,130
+this procedure is very easy to perform and allowed
+
+479
+00:33:06,130 --> 00:33:07,970
+recovery for good number of progressive
+
+480
+00:33:07,970 --> 00:33:14,430
+spermatozoaفي مجموعة Normal Spermatozoa أو مجموعة
+
+481
+00:33:14,430 --> 00:33:22,490
+Normal Spermic طبعاً في البداية هذه الطريقة لديها
+
+482
+00:33:22,490 --> 00:33:25,530
+عديد من المفاتيح منها على سبيل المثال إنه بيعمل
+
+483
+00:33:25,530 --> 00:33:27,870
+reduction في percentage of normal chromatin
+
+484
+00:33:27,870 --> 00:33:31,610
+condensation in spermatozoa بيعمل why pellets
+
+485
+00:33:31,610 --> 00:33:35,330
+spermatozoa are in close contact with other cell
+
+486
+00:33:35,330 --> 00:33:38,450
+depressed anticocyte at the bottom of the tube
+
+487
+00:33:38,620 --> 00:33:42,460
+beginning exposure to the high level of ROS طبعا
+
+488
+00:33:42,460 --> 00:33:46,880
+طالما فقط ال spermatozoa التي تتميز بالجودموتالي
+
+489
+00:33:46,880 --> 00:33:50,580
+التي تسبح في الأعلى إذا أنا هفقد كمية كبيرة جدا من
+
+490
+00:33:50,580 --> 00:33:54,360
+ال spermatozoa في ال centrifugation و هدلها في
+
+491
+00:33:54,360 --> 00:33:58,260
+البلد وجودها في البلد يعني قريبة من ال leukocyte
+
+492
+00:33:58,260 --> 00:34:01,640
+قريبة من ال leukocyte يعني قريبة من ال ROS قريبة
+
+493
+00:34:01,640 --> 00:34:05,500
+من ال ROS يعني عندي ال ROS هيأثّر ال spermatozoa و
+
+494
+00:34:05,500 --> 00:34:08,970
+هيعمل لي destructure لهاعشان كده بلاقي عدد
+
+495
+00:34:08,970 --> 00:34:13,890
+الحيوانات المنوية التي تسبح للأعلى قليل جداً قد
+
+496
+00:34:13,890 --> 00:34:17,370
+تكون Normal Motile ولكن قد لا تكون Normal
+
+497
+00:34:17,370 --> 00:34:20,570
+Morphology أو Normal Sperm Condensation المادة
+
+498
+00:34:20,570 --> 00:34:24,390
+الوراثية مش هتكون .. ممكن ما تكونش Normal بنسبة
+
+499
+00:34:24,390 --> 00:34:29,410
+100% فبالتالي هذه تُعتبر من الطرق التي تُستخدم
+
+500
+00:34:29,410 --> 00:34:33,870
+طبعا أكثر استخدام هذه الطريقة في عملية الـ I.O.I
+
+501
+00:34:33,870 --> 00:34:38,880
+بسميتها Intra-UterineIn Semination كيف انا هتشتغل
+
+502
+00:34:38,880 --> 00:34:42,940
+هذه الفريقة و كيف بتتم ببساطة جدا بجيب عينة ال
+
+503
+00:34:42,940 --> 00:34:47,660
+seminal fluid بعمل mixing بينها و بين ال media
+
+504
+00:34:47,660 --> 00:34:52,880
+اسمها IOI media بنسبة 1 إلى 2 شو يعني 1 إلى 2؟
+
+505
+00:34:52,880 --> 00:34:58,280
+بمعنى اخر انا عندي 1ml سيمن بضيف عليها 2ml washing
+
+506
+00:34:58,280 --> 00:35:03,200
+culture media او IOI media او بسموها washing media
+
+507
+00:35:04,630 --> 00:35:08,670
+أو swarm up media اللي هي مسميات كتيرة عندى 1 مل
+
+508
+00:35:08,670 --> 00:35:12,530
+بضيف عليها 2 مل من ال media بعمل mixing طبعا هذا
+
+509
+00:35:12,530 --> 00:35:15,450
+في ال sterilized tube و بعمله centrifugation لمدت
+
+510
+00:35:15,450 --> 00:35:22,230
+10 دقائق على 2200 rpm بعد كده بتخلص من كل ال
+
+511
+00:35:22,230 --> 00:35:25,090
+supernatant ماليش علاقة بيه بعمله discard و moving
+
+512
+00:35:25,090 --> 00:35:31,030
+بعدين بضيف عليه نفس ال media بكمية معينة 1 مل 1.5
+
+513
+00:35:31,030 --> 00:35:35,430
+مل بناء على كمية البلة الموجودةولكن عملية إضافة ال
+
+514
+00:35:35,430 --> 00:35:38,950
+media هنا بت cool بشكل very slowly وعلى الجدار
+
+515
+00:35:38,950 --> 00:35:42,090
+الداخل للأنبوبة يعني باخد بالاسترالي و أضربها 1
+
+516
+00:35:42,090 --> 00:35:47,410
+mil أو 2 mil بإنها ماجدش عندي حجم ال pellet عندي
+
+517
+00:35:47,410 --> 00:35:50,370
+حجم ال pellet أو ال sediment 1 mil باخد 2 mil و
+
+518
+00:35:50,370 --> 00:35:54,650
+بميل الأنبوبة و بنزل السائل أو ال solution أو ال
+
+519
+00:35:54,650 --> 00:35:58,510
+media على الجدار الداخل للأنبوبة عشان مايصيرش drop
+
+520
+00:35:58,510 --> 00:36:05,160
+مرة واحدة مع ال sedimentبعد كده باخد الأنبوبة هذه
+
+521
+00:36:05,160 --> 00:36:11,460
+و بضيف ثراج بشكل مائل بزاوية 45 درجة و بحطه في ال
+
+522
+00:36:11,460 --> 00:36:17,540
+incubator لمدة 45 دقيقة على 37 درجة مائوية طبعا
+
+523
+00:36:17,540 --> 00:36:23,540
+هذه الإيمالة أو بزاوية 45 بالـdenis landship بساعد
+
+524
+00:36:23,540 --> 00:36:28,840
+ال spermatozoa أنها تسبح بسهولة نحو السطح فبالتالي
+
+525
+00:36:28,840 --> 00:36:32,900
+ما بيكون فيه قوة كبيرة جدابتواجد الـ spermatozoa
+
+526
+00:36:32,900 --> 00:36:36,140
+تقيق عملية السباحة للأعلى بالفعل الـ gravity فأنا
+
+527
+00:36:36,140 --> 00:36:39,140
+عملت عملية إيمان لإلها عشان أتقلل المسافة اللي
+
+528
+00:36:39,140 --> 00:36:42,340
+هتقطعها ال spermatozoa وما أجهد ال sperm لإن أنا
+
+529
+00:36:42,340 --> 00:36:46,360
+محتاج حركته في عملية ال fertilization بعد ما اتخلص
+
+530
+00:36:46,360 --> 00:36:53,200
+ال 40 أو ال 45 دقيقة باجي بطلع ال أنبوبة برفعها
+
+531
+00:36:53,200 --> 00:36:56,840
+باجي supernatant بعد ما كانت clear صار تربط معناه
+
+532
+00:36:56,840 --> 00:37:00,900
+في spermatozoa صعدت للأعلىباخد كل الـ supernatant
+
+533
+00:37:00,900 --> 00:37:03,780
+اللي فيه spermatozoon و بضيفه في الـ sterile test
+
+534
+00:37:03,780 --> 00:37:08,160
+tube و بعمل evaluation للعينة من حيث ال count و من
+
+535
+00:37:08,160 --> 00:37:11,700
+حيث ال motility جدّيش فيها sperm و جدّيش فيها
+
+536
+00:37:11,700 --> 00:37:15,470
+متغير ال spermطبعاً هذه صورة بتوضح الكلام فيها
+
+537
+00:37:15,470 --> 00:37:18,490
+عندى test tube ضفت العينة واحد منه وضفت عليها
+
+538
+00:37:18,490 --> 00:37:21,890
+اتنين من ال media عملتلها mixing ثم تخلصت
+
+539
+00:37:21,890 --> 00:37:26,450
+centrifugation وتخلصت من السبرانيتل ضفت media أخرى
+
+540
+00:37:26,450 --> 00:37:30,590
+تتناسب مع كمية ال sediment الموجودة ضفتها وقمت
+
+541
+00:37:30,590 --> 00:37:34,250
+بوضعها في راك بزاوية 45 درجة مئوية ودخلتها ال
+
+542
+00:37:34,250 --> 00:37:38,910
+incubator على 37 درجة .. عفوا ضفتها في الراك
+
+543
+00:37:38,910 --> 00:37:42,990
+بزاوية 45 درجةبعدين أدخلت الراك بالأنبوبة داخل من
+
+544
+00:37:42,990 --> 00:37:48,850
+كيبيتو على درجة حرارة 37 درجة موية لمدة من 20 ل 40
+
+545
+00:37:48,850 --> 00:37:51,910
+دقيقة بعد كده هرفع الأنبوبة هلاجي ال supernatant
+
+546
+00:37:51,910 --> 00:37:55,330
+تيربت بعد ما كان clear دليل أنه في spermatozoon
+
+547
+00:37:55,640 --> 00:37:58,420
+باخد كل ال super net worth اللي موجود بالأعلى دون
+
+548
+00:37:58,420 --> 00:38:02,040
+ما ألامس ال sediment و بضيفها في مبوبة جديدة بعدين
+
+549
+00:38:02,040 --> 00:38:05,380
+باخد منه عشرة micro بعمله assessment علشان أشوف كم
+
+550
+00:38:05,380 --> 00:38:09,080
+في عندي sperm count و كم في عندي motile و كم في
+
+551
+00:38:09,080 --> 00:38:13,500
+عندي عدد من حيث عدد ال sperm طبعا هذه الطريقة
+
+552
+00:38:13,500 --> 00:38:18,080
+مابتحتاج skill معينة طريقة سهلة جدا رخيصة جدا
+
+553
+00:38:18,080 --> 00:38:23,120
+مابتحتاج لدست تيوب و media و أكثر استخدامها لل IVF
+
+554
+00:38:23,120 --> 00:38:24,920
+التقليدي بالإضافة
+
+555
+00:38:30,570 --> 00:38:35,230
+الطريقة التالتة التي تعتبر هي أكثر الطرق استخداما
+
+556
+00:38:35,230 --> 00:38:38,630
+طريقة الـDensity Gradient Centrifugation يعني
+
+557
+00:38:38,630 --> 00:38:43,050
+الفصل باستخدام الكثافة المختلفة أو طبقة الكثافية
+
+558
+00:38:43,050 --> 00:38:49,740
+المختلفة طبعاهذه التقنية هي تقنية مهمة جدًا لتختار
+
+559
+00:38:49,740 --> 00:38:53,640
+عدد كبير أو عدد كبير من مطايل السبرماتوزوة في حالة
+
+560
+00:38:53,640 --> 00:38:55,100
+عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد
+
+561
+00:38:55,100 --> 00:38:55,920
+عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد
+
+562
+00:38:55,920 --> 00:38:57,260
+عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد
+
+563
+00:38:57,260 --> 00:38:57,980
+عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد
+
+564
+00:38:57,980 --> 00:39:08,900
+عدد عدد عدد عدد عدد عدد عدد عدد عدد
+
+565
+00:39:08,900 --> 00:39:09,520
+ع
+
+566
+00:39:14,210 --> 00:39:17,850
+العينات التي تُصنف على أنها Oligospermia أو
+
+567
+00:39:17,850 --> 00:39:23,070
+Teratospermia أو Asinodyspermia طبعاً، in this
+
+568
+00:39:23,070 --> 00:39:25,890
+method, good quality sperm can be separated from
+
+569
+00:39:25,890 --> 00:39:29,270
+dead sperm أمر طبيعي، from leukocyte، from other
+
+570
+00:39:29,270 --> 00:39:32,490
+compounds of the seminal plasma by density
+
+571
+00:39:32,490 --> 00:39:35,770
+discontinuous gradient ماهي المقصود فيه؟ ال
+
+572
+00:39:35,770 --> 00:39:39,090
+density discontinuous gradient يعني كثافة متدرجة
+
+573
+00:39:39,090 --> 00:39:44,290
+غير متصلةمن حيث الكثافة ما بقول كل لنبوبة 90%
+
+574
+00:39:44,290 --> 00:39:48,090
+كثافتها هنحكي عنها إشي عن كثافة متدرجة أو كثافة
+
+575
+00:39:48,090 --> 00:39:52,650
+غير متواصلة فكرتها إنه أنا بفصل ال good sperm من
+
+576
+00:39:52,650 --> 00:39:56,430
+حيث ال quality عن ال other spermatozoa عن ال bad
+
+577
+00:39:56,430 --> 00:39:59,270
+quality sperm عن ال dead sperm عن ال ecocide عن ال
+
+578
+00:39:59,270 --> 00:40:02,210
+depress عن ال other material فكيف أنا بدي أشتغلها
+
+579
+00:40:02,210 --> 00:40:06,450
+ببساطة جدا ببساطة جدا بجيب test tube بضيف فيها
+
+580
+00:40:06,450 --> 00:40:11,020
+عندي two type of media نفس ال mediaولكن with
+
+581
+00:40:11,020 --> 00:40:13,960
+different concentrations كدا بسميها two types of
+
+582
+00:40:13,960 --> 00:40:18,780
+media من حيث ال density وليس من حيث النوع two
+
+583
+00:40:18,780 --> 00:40:23,320
+types of media according to density not according
+
+584
+00:40:23,320 --> 00:40:27,400
+to composition فنفرض إن ال media الأولى تركيزة 40
+
+585
+00:40:27,400 --> 00:40:30,860
+و ال media الأولى كثافتها 40 و ال media التانية
+
+586
+00:40:30,860 --> 00:40:38,080
+كثافتها 80 فباخد ببساطة جدا بجيب ال test tube بضيف
+
+587
+00:40:38,080 --> 00:40:43,520
+عليهاtop layer 40% يعني بمعنى أخر بجيب ال media
+
+588
+00:40:43,520 --> 00:40:47,680
+اللي كثافتها 80% و أضيف واحد منه بعدين كده بجيب ال
+
+589
+00:40:47,680 --> 00:40:51,920
+media اللي كثافتها 40% و أضيف واحد منه آخر بشرط أن
+
+590
+00:40:51,920 --> 00:40:55,500
+الإضافة تكون بشكل مائل عشان مايصير strong mix
+
+591
+00:40:55,500 --> 00:41:00,460
+between two type of media فهتكون ال layer السفلة
+
+592
+00:41:00,460 --> 00:41:04,800
+لها علاقة بال media اللي كثافتها 80% بينما ال
+
+593
+00:41:04,800 --> 00:41:08,720
+layer العلوية لها علاقة بال media اللي كثافتها 40%
+
+594
+00:41:09,440 --> 00:41:13,060
+بعدين بجيب 2ml .. طبعا خدوا بالكوا النسبة لازم
+
+595
+00:41:13,060 --> 00:41:17,000
+تكون 1 إلى 1 حطت 1ml من ال media الأولى هتكون 1ml
+
+596
+00:41:17,000 --> 00:41:20,700
+من ال media التانية و 1ml من ال seminal fluid أو
+
+597
+00:41:20,700 --> 00:41:28,020
+العينة حطت 2ml 80% و 2ml 40% بعدين ضفت العينة و
+
+598
+00:41:28,020 --> 00:41:33,270
+قلت هتكون 2ml من عينة ال semen ما بعمل mix؟وعملية
+
+599
+00:41:33,270 --> 00:41:36,690
+الإضافة بتكون بشكل very slowly على الجدار الداخل
+
+600
+00:41:36,690 --> 00:41:40,350
+للأنبوبة عشان مايصيرش mix بين الطبقات الداخلية من
+
+601
+00:41:40,350 --> 00:41:46,370
+الأسفل لأعلى media 8% و2% و140% ورقم 3 seminal
+
+602
+00:41:46,370 --> 00:41:51,410
+flow بعمله centrifugation على 300xg لمدة 20 minute
+
+603
+00:41:51,410 --> 00:41:56,430
+بطلّع الأنبوبة بكل بساطة و بدون استأجال عشان
+
+604
+00:41:56,430 --> 00:42:01,720
+ماعملش mix حلاجة في عندي انقسام separatingمن
+
+605
+00:42:01,720 --> 00:42:04,860
+الأعلى للأسفل سيكون في الأعلى الـ Seminal Fluid
+
+606
+00:42:04,860 --> 00:42:08,220
+يليه بالـ sperm, other debris, bacteria,
+
+607
+00:42:08,420 --> 00:42:11,960
+dipethylamin, immature, non mature, spermatozoa,
+
+608
+00:42:12,080 --> 00:42:16,160
+pellet, other target يعني سيكون عندي فقط طبقتين
+
+609
+00:42:16,160 --> 00:42:20,640
+الطبقة العلوية هي الـ Seminal Fluid بكل ما ذكرنا و
+
+610
+00:42:20,640 --> 00:42:23,260
+الطبقة السفلية هي ال pellet اللي فيها ال target
+
+611
+00:42:23,260 --> 00:42:27,140
+بأخد
+
+612
+00:42:27,140 --> 00:42:31,930
+كل الطبقة العلويةبدون أعمل أي touch لل ballot و
+
+613
+00:42:31,930 --> 00:42:36,730
+برميها بعملها discard we don't need it بعد كده
+
+614
+00:42:36,730 --> 00:42:41,530
+transfer the spare ballot to the new tube and then
+
+615
+00:42:41,530 --> 00:42:45,210
+add 5ml of your spare wash في ناس بتاخد ال ballot
+
+616
+00:42:45,210 --> 00:42:49,410
+لتسة تيوب جديدة و في ناس أصلا بتضيف على ال ballot
+
+617
+00:42:49,410 --> 00:42:54,650
+مباشرة و بتعملها mixing من pure media و pure wash
+
+618
+00:42:54,650 --> 00:42:56,870
+media خمسة ميل بضيفه على ال ballot بعمله
+
+619
+00:42:56,870 --> 00:43:00,950
+resuspensioncentrifugation لمدة 10 دقائق على 500
+
+620
+00:43:00,950 --> 00:43:06,190
+XG بعمل remove all the pure sperm washing except
+
+621
+00:43:06,190 --> 00:43:09,730
+the last one mil بمعنى أخر بعد ما أضفت الخمسة mil
+
+622
+00:43:09,730 --> 00:43:13,290
+وعملت centrifugation لمدة عشر دقائق باخد ال test
+
+623
+00:43:13,290 --> 00:43:16,950
+tube برفع أربع mil من الخمسة mil برميهم و بخل أخر
+
+624
+00:43:16,950 --> 00:43:20,450
+واحد mil اللي فيه spermatozoa اللي أنا بديها اللي
+
+625
+00:43:20,450 --> 00:43:24,210
+سميتها target spermatozoa ممكن أخد منها عشرة micro
+
+626
+00:43:24,210 --> 00:43:29,210
+و أعمل evaluation للعينة و أشوف كميةالـ sperm من
+
+627
+00:43:29,210 --> 00:43:32,950
+حيث ال concentration وقداش كمية ال sperm من حيث
+
+628
+00:43:32,950 --> 00:43:38,130
+motility as percentage طبعا هذه شكل ال conical
+
+629
+00:43:38,130 --> 00:43:43,970
+test tube أنا أضفت ال layer الأولى 2 mil وليكن من
+
+630
+00:43:43,970 --> 00:43:49,690
+الميدة التركيزة أو كثفتها 80 بعض الأحيان 90 وطبقة
+
+631
+00:43:49,690 --> 00:43:53,350
+تانية 2 mil من الميدة اللي كثفتها 40وبعض الأحيان
+
+632
+00:43:53,350 --> 00:43:56,530
+طبعا 45 فهو بنادأ بناء على شركة على شركة في شركة
+
+633
+00:43:56,530 --> 00:43:58,970
+بتعمل 80 اربعين وفي شركة بتعمل 90 اربعين و45
+
+634
+00:43:58,970 --> 00:44:03,710
+اربعين وكذا بعد انضفت اتنين ميل من العينة ادخلتهم
+
+635
+00:44:03,710 --> 00:44:06,010
+ال centrifugation بعد انتهاء ال centrifugation
+
+636
+00:44:06,010 --> 00:44:09,570
+اللي جات فيه عند كل السيمون الفلويد في الأعلى بما
+
+637
+00:44:09,570 --> 00:44:14,340
+يحتوي من material unwantedوالـ Target ماتيريا
+
+638
+00:44:14,340 --> 00:44:17,440
+الموجودة في الـ Sediment بتخلص من الـ Supernatant
+
+639
+00:44:17,440 --> 00:44:21,720
+وبضيف عليها خمسة مل من Pure Washing Solution
+
+640
+00:44:21,720 --> 00:44:25,340
+بعملها Mixing و Centrifugation بعد كده بتخلص من
+
+641
+00:44:25,340 --> 00:44:29,520
+أربع مل وبترك الواحد مل كما هو و هو اللي فيه
+
+642
+00:44:29,520 --> 00:44:34,400
+Target إذا الواحد مل الأخير هو اللي فيه Target
+
+643
+00:44:34,400 --> 00:44:38,500
+Spermatozoa with high quality باخد منها عشرة micro
+
+644
+00:44:38,500 --> 00:44:41,420
+بعملها evaluation assessment عشان يشوف كدهش ال
+
+645
+00:44:41,420 --> 00:44:44,410
+total countكداش ال concentration، كداش ال
+
+646
+00:44:44,410 --> 00:44:47,330
+motility، كداش ال progressiveotype، و كده بتكون
+
+647
+00:44:47,330 --> 00:44:52,930
+العين جاهزة لل exit سنستكفي بهذا القدر ان شاء الله
+
+648
+00:44:52,930 --> 00:44:58,090
+على أمل أن نلتقي في محاضرات مستقبلية تم تم في حفظ
+
+649
+00:44:58,090 --> 00:44:59,270
+الوريعات
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/9mspvrq6uv4_raw.json b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/9mspvrq6uv4_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..0ec6805943855cdf77512aa6af62d76bf87bbb33
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/9mspvrq6uv4_raw.json
@@ -0,0 +1 @@
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28671, 20666, 39184, 14421, 2071, 33612, 327, 9154, 5551, 8592, 3224, 2288, 11296, 1018, 610, 29958, 6156, 6027, 39184, 1018, 610, 29958, 20449, 8315, 11296, 14739], "avg_logprob": -0.17472825905551082, "compression_ratio": 1.5766129032258065, "no_speech_prob": 3.916025161743164e-05, "words": [{"start": 88.61, "end": 89.29, "word": "IVF", "probability": 0.61834716796875}, {"start": 89.29, "end": 89.51, "word": " In", "probability": 0.267822265625}, {"start": 89.51, "end": 89.81, "word": " Vitro", "probability": 0.856689453125}, {"start": 89.81, "end": 90.49, "word": " Fertilization", "probability": 0.9022216796875}, {"start": 90.49, "end": 91.75, "word": " ولكن", "probability": 0.7445068359375}, {"start": 91.75, "end": 92.49, "word": " قبل", "probability": 0.967041015625}, {"start": 92.49, "end": 92.71, "word": " أن", "probability": 0.92529296875}, {"start": 92.71, "end": 93.27, "word": " نتحدث", "probability": 0.9798583984375}, {"start": 93.27, "end": 93.47, "word": " عن", "probability": 0.99560546875}, {"start": 93.47, "end": 93.81, "word": " هذه", "probability": 0.97509765625}, {"start": 93.81, "end": 94.57, "word": " الآليات", "probability": 0.858154296875}, {"start": 94.57, "end": 95.81, "word": " وهذه", "probability": 0.7213134765625}, {"start": 95.81, "end": 96.29, "word": " الطرق", "probability": 0.8221028645833334}, {"start": 96.29, "end": 96.59, "word": " التي", "probability": 0.93212890625}, {"start": 96.59, "end": 97.05, "word": " يمكن", "probability": 0.96630859375}, {"start": 97.05, "end": 97.27, "word": " أن", "probability": 0.634765625}, {"start": 97.27, "end": 97.91, "word": " تستخدم", "probability": 0.9775390625}, {"start": 97.91, "end": 98.41, "word": " من", "probability": 0.9453125}, {"start": 98.41, "end": 98.71, "word": " أجل", "probability": 0.94677734375}, {"start": 98.71, "end": 99.25, "word": " تحضير", "probability": 0.98193359375}, {"start": 99.25, "end": 99.65, "word": " عينة", "probability": 0.92041015625}, {"start": 99.65, "end": 100.19, "word": " السائل", "probability": 0.98095703125}, {"start": 100.19, "end": 100.89, "word": " دعونا", "probability": 0.9498291015625}, {"start": 100.89, "end": 101.43, "word": " نتكلم", "probability": 0.9915771484375}, {"start": 101.43, "end": 101.65, "word": " عن", "probability": 0.99560546875}, {"start": 101.65, "end": 102.27, "word": " مصالحات", "probability": 0.9552734375}, {"start": 102.27, "end": 102.67, "word": " طبية", "probability": 0.8836263020833334}, {"start": 102.67, "end": 103.17, "word": " مهمة", "probability": 0.97998046875}, {"start": 103.17, "end": 104.01, "word": " جداً", "probability": 0.7620442708333334}, {"start": 104.01, "end": 104.25, "word": " لها", "probability": 0.93798828125}, {"start": 104.25, "end": 104.71, "word": " علاقة", "probability": 0.98681640625}, {"start": 104.71, "end": 105.25, "word": " بالـ", "probability": 0.6712646484375}, {"start": 105.25, "end": 105.75, "word": " XY", "probability": 0.3736572265625}, {"start": 105.75, "end": 107.51, "word": " ولها", "probability": 0.6315104166666666}, {"start": 107.51, "end": 107.97, "word": " علاقة", "probability": 0.9879557291666666}, {"start": 107.97, "end": 108.25, "word": " بالـ", "probability": 0.55633544921875}, {"start": 108.25, "end": 108.55, "word": " Seminal", "probability": 0.7142333984375}, {"start": 108.55, "end": 109.29, "word": " Fluid", "probability": 0.893310546875}, {"start": 109.29, "end": 109.69, "word": " من", "probability": 0.94482421875}, {"start": 109.69, "end": 110.53, "word": " أشهرها", "probability": 0.99501953125}, {"start": 110.53, "end": 111.51, "word": " Aspermia", "probability": 0.79736328125}, {"start": 111.51, "end": 112.39, "word": " فالـ", "probability": 0.8232421875}, {"start": 112.39, "end": 112.85, "word": " Aspermia", "probability": 0.9737955729166666}, {"start": 112.85, "end": 113.35, "word": " معناها", "probability": 0.9744466145833334}, {"start": 113.35, "end": 113.57, "word": " أن", "probability": 0.69970703125}], "temperature": 1.0}, {"id": 5, "seek": 13853, "start": 113.97, "end": 138.53, "text": "عدم وجود seminal fluid هذا الرجل لا يستطيع أن يعمل ejaculation فبالتالي في عنده seminal fluid ال volume الخاص فيه zero مافي عنده seminal أو semen volume مافي عنده semen volume so the definition of a spermia is no seminal fluid وينطبق عليها مصطلحين hypospermia وhyperspermia", "tokens": [22488, 2304, 49610, 23328, 4361, 2071, 9113, 23758, 34892, 7435, 1211, 20193, 7251, 14851, 9566, 40228, 14739, 7251, 25957, 1211, 10012, 326, 2776, 6156, 3555, 6027, 2655, 6027, 1829, 8978, 43242, 3224, 4361, 2071, 9113, 2423, 5523, 33962, 33546, 8978, 3224, 4018, 19446, 41185, 43242, 3224, 4361, 2071, 34051, 4361, 268, 5523, 19446, 41185, 43242, 3224, 4361, 268, 5523, 370, 264, 7123, 295, 257, 24152, 29958, 307, 572, 4361, 2071, 9113, 4032, 9957, 9566, 3555, 4587, 25894, 11296, 3714, 9381, 9566, 1211, 5016, 9957, 7420, 329, 610, 29958, 4032, 3495, 21819, 610, 29958], "avg_logprob": -0.18334441695441592, "compression_ratio": 1.6883720930232557, "no_speech_prob": 1.1920928955078125e-07, "words": [{"start": 113.97, "end": 114.55, "word": "عدم", "probability": 0.740966796875}, {"start": 114.55, "end": 115.09, "word": " وجود", "probability": 0.862060546875}, {"start": 115.09, "end": 115.49, "word": " seminal", "probability": 0.779052734375}, {"start": 115.49, "end": 115.91, "word": " fluid", "probability": 0.92041015625}, {"start": 115.91, "end": 116.17, "word": " هذا", "probability": 0.72998046875}, {"start": 116.17, "end": 116.73, "word": " الرجل", "probability": 0.931640625}, {"start": 116.73, "end": 116.89, "word": " لا", "probability": 0.7490234375}, {"start": 116.89, "end": 117.43, "word": " يستطيع", "probability": 0.8883056640625}, {"start": 117.43, "end": 117.83, "word": " أن", "probability": 0.5439453125}, {"start": 117.83, "end": 118.37, "word": " يعمل", "probability": 0.9832356770833334}, {"start": 118.37, "end": 119.23, "word": " ejaculation", "probability": 0.9357096354166666}, {"start": 119.23, "end": 120.15, "word": " فبالتالي", "probability": 0.8733723958333334}, {"start": 120.15, "end": 120.35, "word": " في", "probability": 0.8486328125}, {"start": 120.35, "end": 120.71, "word": " عنده", "probability": 0.6676025390625}, {"start": 120.71, "end": 121.03, "word": " seminal", "probability": 0.9130859375}, {"start": 121.03, "end": 121.39, "word": " fluid", "probability": 0.94189453125}, {"start": 121.39, "end": 121.53, "word": " ال", "probability": 0.77880859375}, {"start": 121.53, "end": 121.77, "word": " volume", "probability": 0.94091796875}, {"start": 121.77, "end": 122.21, "word": " الخاص", "probability": 0.78076171875}, {"start": 122.21, "end": 122.45, "word": " فيه", "probability": 0.947509765625}, {"start": 122.45, "end": 122.77, "word": " zero", "probability": 0.3916015625}, {"start": 122.77, "end": 123.39, "word": " مافي", "probability": 0.868896484375}, {"start": 123.39, "end": 124.01, "word": " عنده", "probability": 0.94580078125}, {"start": 124.01, "end": 124.65, "word": " seminal", "probability": 0.919189453125}, {"start": 124.65, "end": 125.25, "word": " أو", "probability": 0.65869140625}, {"start": 125.25, "end": 125.83, "word": " semen", "probability": 0.6065673828125}, {"start": 125.83, "end": 126.73, "word": " volume", "probability": 0.9609375}, {"start": 126.73, "end": 127.03, "word": " مافي", "probability": 0.748779296875}, {"start": 127.03, "end": 127.33, "word": " عنده", "probability": 0.955810546875}, {"start": 127.33, "end": 127.77, "word": " semen", "probability": 0.770263671875}, {"start": 127.77, "end": 128.21, "word": " volume", "probability": 0.98974609375}, {"start": 128.21, "end": 128.71, "word": " so", "probability": 0.31494140625}, {"start": 128.71, "end": 129.25, "word": " the", "probability": 0.73779296875}, {"start": 129.25, "end": 129.73, "word": " definition", "probability": 0.935546875}, {"start": 129.73, "end": 130.03, "word": " of", "probability": 0.978515625}, {"start": 130.03, "end": 130.21, "word": " a", "probability": 0.4462890625}, {"start": 130.21, "end": 130.69, "word": " spermia", "probability": 0.9296875}, {"start": 130.69, "end": 131.49, "word": " is", "probability": 0.9658203125}, {"start": 131.49, "end": 132.15, "word": " no", "probability": 0.84912109375}, {"start": 132.15, "end": 132.83, "word": " seminal", "probability": 0.63818359375}, {"start": 132.83, "end": 133.35, "word": " fluid", "probability": 0.90380859375}, {"start": 133.35, "end": 134.39, "word": " وينطبق", "probability": 0.96416015625}, {"start": 134.39, "end": 134.85, "word": " عليها", "probability": 0.970947265625}, {"start": 134.85, "end": 135.69, "word": " مصطلحين", "probability": 0.9881998697916666}, {"start": 135.69, "end": 137.19, "word": " hypospermia", "probability": 0.841552734375}, {"start": 137.19, "end": 138.53, "word": " وhyperspermia", "probability": 0.9166015625}], "temperature": 1.0}, {"id": 6, "seek": 16744, "start": 138.78, "end": 167.44, "text": "الـ Hyper-Spermia زيادة في الـ volume في الحجم بيتجاوز الـ 5.5 ملي لتر أما الـ Hypo-Spermia نقصان في الـ volume لكي يكون أقل من 2 ملي لتر لأننا اتفقنا أن الـ normal volume للـ seminal fluid 2 ملي لتر فزيادته و نقصانه له مصطلح معين يليه مصطلح مهم جدا و هو أكثر انتشارا هو عبارة عن الـ Oligospermia", "tokens": [6027, 39184, 29592, 12, 50, 610, 29958, 30767, 1829, 18513, 3660, 8978, 2423, 39184, 5523, 8978, 21542, 7435, 2304, 4724, 36081, 7435, 995, 2407, 11622, 2423, 39184, 1025, 13, 20, 3714, 20292, 5296, 2655, 2288, 5551, 15042, 2423, 39184, 5701, 2259, 12, 50, 610, 29958, 8717, 4587, 9381, 7649, 8978, 2423, 39184, 5523, 5296, 4117, 1829, 7251, 30544, 5551, 4587, 1211, 9154, 568, 3714, 20292, 5296, 2655, 2288, 5296, 33456, 8315, 1975, 2655, 5172, 4587, 8315, 14739, 2423, 39184, 2710, 5523, 24976, 39184, 4361, 2071, 9113, 568, 3714, 20292, 5296, 2655, 2288, 6156, 11622, 1829, 18513, 47395, 4032, 8717, 4587, 9381, 7649, 3224, 46740, 3714, 9381, 9566, 1211, 5016, 20449, 9957, 7251, 20292, 3224, 3714, 9381, 9566, 1211, 5016, 3714, 16095, 10874, 28259, 4032, 31439, 5551, 4117, 49115, 16472, 2655, 8592, 9640, 995, 31439, 6225, 3555, 9640, 3660, 18871, 2423, 39184, 422, 5073, 329, 610, 29958], "avg_logprob": -0.1319090136054422, "compression_ratio": 1.8134920634920635, "no_speech_prob": 1.7881393432617188e-07, "words": [{"start": 138.78, "end": 139.12, "word": "الـ", "probability": 0.962646484375}, {"start": 139.12, "end": 139.28, "word": " Hyper", "probability": 0.38134765625}, {"start": 139.28, "end": 139.84, "word": "-Spermia", "probability": 0.72637939453125}, {"start": 139.84, "end": 140.42, "word": " زيادة", "probability": 0.965087890625}, {"start": 140.42, "end": 140.56, "word": " في", "probability": 0.974609375}, {"start": 140.56, "end": 140.88, "word": " الـ", "probability": 0.70703125}, {"start": 140.88, "end": 141.12, "word": " volume", "probability": 0.6357421875}, {"start": 141.12, "end": 141.32, "word": " في", "probability": 0.426025390625}, {"start": 141.32, "end": 141.78, "word": " الحجم", "probability": 0.9947916666666666}, {"start": 141.78, "end": 142.86, "word": " بيتجاوز", "probability": 0.8758951822916666}, {"start": 142.86, "end": 143.3, "word": " الـ", "probability": 0.670654296875}, {"start": 143.3, "end": 143.58, "word": " 5", "probability": 0.83251953125}, {"start": 143.58, "end": 144.82, "word": ".5", "probability": 0.9853515625}, {"start": 144.82, "end": 145.12, "word": " ملي", "probability": 0.65380859375}, {"start": 145.12, "end": 145.48, "word": " لتر", "probability": 0.84130859375}, {"start": 145.48, "end": 146.12, "word": " أما", "probability": 0.92138671875}, {"start": 146.12, "end": 146.32, "word": " الـ", "probability": 0.976318359375}, {"start": 146.32, "end": 146.66, "word": " Hypo", "probability": 0.65380859375}, {"start": 146.66, "end": 147.12, "word": "-Spermia", "probability": 0.887939453125}, {"start": 147.12, "end": 148.04, "word": " نقصان", "probability": 0.9766845703125}, {"start": 148.04, "end": 148.2, "word": " في", "probability": 0.986328125}, {"start": 148.2, "end": 148.4, "word": " الـ", "probability": 0.727294921875}, {"start": 148.4, "end": 148.7, "word": " volume", "probability": 0.947265625}, {"start": 148.7, "end": 149.3, "word": " لكي", "probability": 0.9347330729166666}, {"start": 149.3, "end": 149.66, "word": " يكون", "probability": 0.987060546875}, {"start": 149.66, "end": 150.1, "word": " أقل", "probability": 0.98291015625}, {"start": 150.1, "end": 150.38, "word": " من", "probability": 0.99462890625}, {"start": 150.38, "end": 151.18, "word": " 2", "probability": 0.9521484375}, {"start": 151.18, "end": 151.78, "word": " ملي", "probability": 0.952392578125}, {"start": 151.78, "end": 152.18, "word": " لتر", "probability": 0.9918619791666666}, {"start": 152.18, "end": 152.82, "word": " لأننا", "probability": 0.8987630208333334}, {"start": 152.82, "end": 153.38, "word": " اتفقنا", "probability": 0.9625}, {"start": 153.38, "end": 153.6, "word": " أن", "probability": 0.814453125}, {"start": 153.6, "end": 153.82, "word": " الـ", "probability": 0.813720703125}, {"start": 153.82, "end": 154.1, "word": " normal", "probability": 0.434814453125}, {"start": 154.1, "end": 154.64, "word": " volume", "probability": 0.97705078125}, {"start": 154.64, "end": 154.94, "word": " للـ", "probability": 0.7529296875}, {"start": 154.94, "end": 155.24, "word": " seminal", "probability": 0.6431884765625}, {"start": 155.24, "end": 155.6, "word": " fluid", "probability": 0.912109375}, {"start": 155.6, "end": 155.9, "word": " 2", "probability": 0.85400390625}, {"start": 155.9, "end": 156.18, "word": " ملي", "probability": 0.928955078125}, {"start": 156.18, "end": 156.56, "word": " لتر", "probability": 0.9938151041666666}, {"start": 156.56, "end": 157.6, "word": " فزيادته", "probability": 0.98251953125}, {"start": 157.6, "end": 158.38, "word": " و", "probability": 0.95068359375}, {"start": 158.38, "end": 159.0, "word": " نقصانه", "probability": 0.91298828125}, {"start": 159.0, "end": 159.36, "word": " له", "probability": 0.97607421875}, {"start": 159.36, "end": 160.02, "word": " مصطلح", "probability": 0.99345703125}, {"start": 160.02, "end": 160.82, "word": " معين", "probability": 0.98974609375}, {"start": 160.82, "end": 162.28, "word": " يليه", "probability": 0.92626953125}, {"start": 162.28, "end": 162.72, "word": " مصطلح", "probability": 0.996875}, {"start": 162.72, "end": 163.04, "word": " مهم", "probability": 0.972900390625}, {"start": 163.04, "end": 163.4, "word": " جدا", "probability": 0.9775390625}, {"start": 163.4, "end": 163.58, "word": " و", "probability": 0.65478515625}, {"start": 163.58, "end": 163.78, "word": " هو", "probability": 0.89404296875}, {"start": 163.78, "end": 164.32, "word": " أكثر", "probability": 0.8702799479166666}, {"start": 164.32, "end": 165.12, "word": " انتشارا", "probability": 0.965234375}, {"start": 165.12, "end": 165.74, "word": " هو", "probability": 0.68994140625}, {"start": 165.74, "end": 166.2, "word": " عبارة", "probability": 0.9918212890625}, {"start": 166.2, "end": 166.4, "word": " عن", "probability": 0.9970703125}, {"start": 166.4, "end": 166.58, "word": " الـ", "probability": 0.89208984375}, {"start": 166.58, "end": 167.44, "word": " Oligospermia", "probability": 0.84423828125}], "temperature": 1.0}, {"id": 7, "seek": 19723, "start": 167.75, "end": 197.23, "text": "الـ Ologospermia معناها نقصان في عدد الحيوانات المنوية في كل واحد مليليتر لكي تصل إلى أقل من 20 مليون حيوان في المليلتر الواحد يليه مصطلح مهم ويعتبر من المصطلحات الأكثر انتشارا و الأهم وهي مصطلح الـ Azospermia فالـ Azospermia معناها عدم وجود سبيرماتوزوة في الـ seminal fluid so the leak of sperm in the semen جدش بتتمثل", "tokens": [6027, 39184, 422, 4987, 329, 610, 29958, 20449, 8315, 11296, 8717, 4587, 9381, 7649, 8978, 6225, 3215, 3215, 21542, 1829, 2407, 7649, 9307, 9673, 1863, 2407, 10632, 8978, 28242, 36764, 24401, 3714, 20292, 20292, 2655, 2288, 5296, 4117, 1829, 6055, 36520, 30731, 5551, 4587, 1211, 9154, 945, 3714, 20292, 11536, 11331, 1829, 2407, 7649, 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مصطلح تاني من المصطلحات الطبية المهمة", "tokens": [35457, 3555, 19753, 34740, 9154, 5551, 35457, 16758, 2423, 39184, 257, 4765, 329, 610, 29958, 35525, 19452, 2423, 39184, 2107, 12, 996, 372, 21673, 2423, 11407, 2423, 12420, 2423, 1374, 299, 541, 259, 36632, 11242, 995, 9122, 25708, 1863, 5172, 13546, 25528, 2423, 6801, 10671, 279, 4386, 2423, 50238, 34051, 2423, 13881, 2423, 2450, 48759, 8211, 29538, 28242, 11296, 6055, 34268, 26890, 9154, 16247, 35457, 16758, 38392, 6055, 33604, 16254, 34683, 3794, 995, 16095, 8978, 11331, 3215, 23328, 2423, 2107, 12, 996, 372, 21673, 257, 4765, 329, 610, 29958, 2423, 2107, 12, 996, 372, 21673, 257, 4765, 329, 610, 29958, 8978, 3714, 9381, 9566, 1211, 5016, 6055, 7649, 1829, 9154, 9673, 9381, 9566, 1211, 5016, 9307, 41950, 3555, 10632, 9673, 16095, 3660], "avg_logprob": -0.27286586092739573, "compression_ratio": 1.8252032520325203, "no_speech_prob": 0.0, "words": [{"start": 717.84, "end": 718.28, "word": "سبب", "probability": 0.91162109375}, 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"word": " حدود", "probability": 0.9303385416666666}, {"start": 737.28, "end": 738.1, "word": " ال", "probability": 0.9521484375}, {"start": 738.1, "end": 738.3, "word": " non", "probability": 0.88916015625}, {"start": 738.3, "end": 738.9, "word": "-obstructive", "probability": 0.9273681640625}, {"start": 738.9, "end": 739.62, "word": " azoospermia", "probability": 0.9619140625}, {"start": 739.62, "end": 739.88, "word": " ال", "probability": 0.80517578125}, {"start": 739.88, "end": 740.04, "word": " non", "probability": 0.88623046875}, {"start": 740.04, "end": 740.74, "word": "-obstructive", "probability": 0.9698486328125}, {"start": 740.74, "end": 741.76, "word": " azoospermia", "probability": 0.97802734375}, {"start": 741.76, "end": 743.28, "word": " في", "probability": 0.88232421875}, {"start": 743.28, "end": 743.72, "word": " مصطلح", "probability": 0.9869140625}, {"start": 743.72, "end": 744.1, "word": " تاني", "probability": 0.9353841145833334}, {"start": 744.1, "end": 744.26, "word": " من", "probability": 0.9814453125}, {"start": 744.26, "end": 744.84, "word": " المصطلحات", "probability": 0.9868977864583334}, {"start": 744.84, "end": 745.26, "word": " الطبية", "probability": 0.8733723958333334}, {"start": 745.26, "end": 745.84, "word": " المهمة", "probability": 0.99658203125}], "temperature": 1.0}, {"id": 28, "seek": 77542, "start": 746.08, "end": 775.42, "text": "as in to zoospermia وهذا المصطلح مقصود فيه أنه فيها عندي ك technologist عندي عينات عينات هذه فيها sperm motility أو sperm motile ولكن في عندي reduction في كمية ونسبة الحيوانات المنوية المتحركة حتى تصل إلى أقل من 40% ورغم أنه ال normal range ل ال total motile 42% عفوا 40%", "tokens": [296, 294, 281, 5721, 329, 610, 29958, 37037, 15730, 9673, 9381, 9566, 1211, 5016, 3714, 4587, 9381, 23328, 8978, 3224, 14739, 3224, 8978, 11296, 18871, 16254, 9122, 1537, 9201, 18871, 16254, 6225, 1829, 8315, 2655, 6225, 1829, 8315, 2655, 29538, 8978, 11296, 32899, 2184, 1140, 34051, 32899, 2184, 794, 35525, 19452, 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"probability": 0.97626953125}, {"start": 764.82, "end": 765.22, "word": " المنوية", "probability": 0.9609375}, {"start": 765.22, "end": 765.9, "word": " المتحركة", "probability": 0.995703125}, {"start": 765.9, "end": 766.58, "word": " حتى", "probability": 0.935302734375}, {"start": 766.58, "end": 766.92, "word": " تصل", "probability": 0.980224609375}, {"start": 766.92, "end": 767.08, "word": " إلى", "probability": 0.91455078125}, {"start": 767.08, "end": 767.42, "word": " أقل", "probability": 0.95751953125}, {"start": 767.42, "end": 767.56, "word": " من", "probability": 0.99560546875}, {"start": 767.56, "end": 767.96, "word": " 40", "probability": 0.94189453125}, {"start": 767.96, "end": 768.32, "word": "%", "probability": 0.966796875}, {"start": 768.32, "end": 768.68, "word": " ورغم", "probability": 0.905029296875}, {"start": 768.68, "end": 769.08, "word": " أنه", "probability": 0.72021484375}, {"start": 769.08, "end": 769.54, "word": " ال", "probability": 0.81396484375}, {"start": 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reduction in the percentage of total sperm motile less than 40% هذا المصطلح بسميه سينو ذي سبيرميا طب شو أسبابه؟ شو العوامل الممكن تسبب و تأثر على ال sperm motility؟ في عندي عدة عوامل من أول عوامل التي تؤثر سلبا عن ال sperm motility ال Vercosyl دوال الخصية اخدوا بالك ال Vercosyl هو عبارة عن تضخم في بعض الأوردة", "tokens": [3555, 3794, 5296, 39184, 32587, 488, 8858, 4, 6156, 3555, 6027, 2655, 6027, 1829, 45164, 20328, 9640, 8978, 18871, 16254, 11004, 294, 264, 9668, 295, 3217, 32899, 2184, 794, 1570, 813, 3356, 4, 23758, 9673, 9381, 9566, 1211, 5016, 4724, 38251, 1829, 3224, 8608, 9957, 2407, 29910, 1829, 8608, 3555, 13546, 2304, 25528, 23032, 3555, 13412, 2407, 5551, 35457, 16758, 3224, 22807, 13412, 2407, 18863, 2407, 10943, 1211, 9673, 43020, 6055, 35457, 3555, 4032, 6055, 10721, 49115, 15844, 2423, 32899, 2184, 1140, 22807, 8978, 18871, 16254, 6225, 41891, 6225, 2407, 10943, 1211, 9154, 5551, 12610, 6225, 2407, 10943, 1211, 38392, 6055, 33604, 49115, 8608, 46152, 995, 18871, 2423, 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"probability": 0.982421875}, {"start": 1307.38, "end": 1308.32, "word": " حاجة", "probability": 0.8551432291666666}, {"start": 1308.32, "end": 1308.76, "word": " بنتسميها", "probability": 0.747802734375}, {"start": 1308.76, "end": 1309.54, "word": " leukospermia", "probability": 0.756256103515625}, {"start": 1309.54, "end": 1310.74, "word": " وليكوسبيرميا", "probability": 0.7987060546875}, {"start": 1310.74, "end": 1311.32, "word": " بيسموها", "probability": 0.9296875}, {"start": 1311.32, "end": 1312.0, "word": " وجود", "probability": 0.971923828125}, {"start": 1312.0, "end": 1312.2, "word": " الـ", "probability": 0.396240234375}, {"start": 1312.2, "end": 1312.66, "word": " leukocyte", "probability": 0.8312174479166666}, {"start": 1312.66, "end": 1313.26, "word": " بكميات", "probability": 0.96875}, {"start": 1313.26, "end": 1313.7, "word": " كبيرة", "probability": 0.9938151041666666}, {"start": 1313.7, "end": 1314.26, "word": " جدًا", "probability": 0.97900390625}, {"start": 1314.26, 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"end": 1382.43, "text": "الـ IVF In Vitro Fertilization فيها عند مصطلح الـ IGSI وفيها عند مصطلح ال IUI إيش يعني ال IUI اختصارها Intrauterine Insemination وهي ببساطة جدا هي إيصال لـ spermatozoa الناضجة إلى الرحم متى بنستخدمها إذا كان في مواجهة عنيفة", "tokens": [6027, 39184, 15967, 37, 682, 22463, 340, 479, 911, 388, 2144, 8978, 11296, 43242, 3714, 9381, 9566, 1211, 5016, 2423, 39184, 26367, 20262, 4032, 41185, 11296, 43242, 3714, 9381, 9566, 1211, 5016, 2423, 286, 46324, 11933, 1829, 8592, 37495, 22653, 2423, 286, 46324, 1975, 46456, 9381, 9640, 11296, 5681, 424, 20314, 533, 682, 405, 2367, 399, 37037, 1829, 4724, 3555, 3794, 41193, 3660, 10874, 28259, 39896, 11933, 1829, 9381, 6027, 5296, 39184, 32899, 2513, 4765, 64, 28239, 46958, 7435, 3660, 30731, 2423, 2288, 35571, 44650, 7578, 44945, 14851, 9778, 40448, 11296, 11933, 15730, 25961, 8978, 3714, 2407, 26108, 3224, 3660, 18871, 33911, 3660], "avg_logprob": -0.21183894503001982, "compression_ratio": 1.511111111111111, 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0.6773681640625}, {"start": 2646.89, "end": 2646.99, "word": " عند", "probability": 0.94970703125}, {"start": 2646.99, "end": 2647.27, "word": " كل", "probability": 0.93212890625}, {"start": 2647.27, "end": 2647.61, "word": " السيمون", "probability": 0.5741780598958334}, {"start": 2647.61, "end": 2648.09, "word": " الفلويد", "probability": 0.7979736328125}, {"start": 2648.09, "end": 2648.25, "word": " في", "probability": 0.7861328125}, {"start": 2648.25, "end": 2648.79, "word": " الأعلى", "probability": 0.9453125}, {"start": 2648.79, "end": 2649.57, "word": " بما", "probability": 0.93603515625}, {"start": 2649.57, "end": 2650.03, "word": " يحتوي", "probability": 0.97998046875}, {"start": 2650.03, "end": 2650.39, "word": " من", "probability": 0.9873046875}, {"start": 2650.39, "end": 2651.21, "word": " material", "probability": 0.401611328125}, {"start": 2651.21, "end": 2651.35, "word": " unwanted", "probability": 0.93701171875}], "temperature": 1.0}, {"id": 97, "seek": 268204, "start": 2652.46, "end": 2682.04, "text": "والـ Target ماتيريا الموجودة في الـ Sediment بتخلص من الـ Supernatant وبضيف عليها خمسة مل من Pure Washing Solution بعملها Mixing و Centrifugation بعد كده بتخلص من أربع مل وبترك الواحد مل كما هو و هو اللي فيه Target إذا الواحد مل الأخير هو اللي فيه Target Spermatozoa with high quality باخد منها عشرة micro بعملها evaluation assessment عشان يشوف كدهش ال total count", "tokens": [2407, 6027, 39184, 24586, 3714, 9307, 13546, 25528, 9673, 29245, 23328, 3660, 8978, 2423, 39184, 31213, 2328, 39894, 9778, 1211, 9381, 9154, 2423, 39184, 4548, 12241, 394, 46599, 11242, 33911, 25894, 11296, 16490, 2304, 3794, 3660, 3714, 1211, 9154, 29474, 3027, 571, 318, 3386, 4724, 25957, 1211, 11296, 12769, 278, 4032, 3408, 22575, 697, 399, 39182, 9122, 3215, 3224, 39894, 9778, 1211, 9381, 9154, 5551, 25513, 3615, 3714, 1211, 46599, 2655, 31747, 2423, 14407, 24401, 3714, 1211, 9122, 15042, 31439, 4032, 31439, 13672, 1829, 8978, 3224, 24586, 11933, 15730, 2423, 14407, 24401, 3714, 1211, 16247, 9778, 13546, 31439, 13672, 1829, 8978, 3224, 24586, 1738, 966, 2513, 4765, 64, 365, 1090, 3125, 4724, 47283, 3215, 9154, 11296, 6225, 8592, 25720, 4532, 4724, 25957, 1211, 11296, 13344, 9687, 6225, 8592, 7649, 7251, 8592, 38688, 9122, 3215, 3224, 8592, 2423, 3217, 1207], "avg_logprob": -0.24553571566939353, "compression_ratio": 1.7087378640776698, "no_speech_prob": 5.960464477539062e-07, "words": [{"start": 2652.46, "end": 2653.2, "word": "والـ", "probability": 0.6673177083333334}, {"start": 2653.2, "end": 2653.58, "word": " Target", "probability": 0.427734375}, {"start": 2653.58, "end": 2654.34, "word": " ماتيريا", "probability": 0.50439453125}, {"start": 2654.34, "end": 2654.88, "word": " الموجودة", "probability": 0.9754638671875}, {"start": 2654.88, "end": 2655.1, "word": " في", "probability": 0.95947265625}, {"start": 2655.1, "end": 2655.3, "word": " الـ", "probability": 0.740966796875}, {"start": 2655.3, "end": 2655.68, "word": " Sediment", "probability": 0.63232421875}, {"start": 2655.68, "end": 2656.54, "word": " بتخلص", "probability": 0.8424072265625}, {"start": 2656.54, "end": 2656.68, "word": " من", "probability": 0.98779296875}, {"start": 2656.68, "end": 2656.82, "word": " الـ", "probability": 0.56494140625}, {"start": 2656.82, "end": 2657.44, "word": " Supernatant", "probability": 0.6832682291666666}, {"start": 2657.44, "end": 2658.28, "word": " وبضيف", "probability": 0.673095703125}, {"start": 2658.28, "end": 2658.8, "word": " عليها", "probability": 0.985595703125}, {"start": 2658.8, "end": 2659.48, "word": " خمسة", "probability": 0.65631103515625}, {"start": 2659.48, "end": 2659.6, "word": " مل", "probability": 0.733642578125}, {"start": 2659.6, "end": 2659.86, "word": " من", "probability": 0.9873046875}, {"start": 2659.86, "end": 2660.42, "word": " Pure", "probability": 0.513671875}, {"start": 2660.42, "end": 2661.08, "word": " Washing", "probability": 0.866943359375}, {"start": 2661.08, "end": 2661.72, "word": " Solution", "probability": 0.73486328125}, {"start": 2661.72, "end": 2662.56, "word": " بعملها", "probability": 0.9111328125}, {"start": 2662.56, "end": 2662.94, "word": " Mixing", "probability": 0.854248046875}, {"start": 2662.94, "end": 2663.04, "word": " و", "probability": 0.94677734375}, {"start": 2663.04, "end": 2663.8, "word": " Centrifugation", "probability": 0.8455810546875}, {"start": 2663.8, "end": 2664.4, "word": " بعد", "probability": 0.8916015625}, {"start": 2664.4, "end": 2664.66, "word": " كده", "probability": 0.9737955729166666}, {"start": 2664.66, "end": 2665.22, "word": " بتخلص", "probability": 0.951904296875}, {"start": 2665.22, "end": 2665.34, "word": " من", "probability": 0.994140625}, {"start": 2665.34, "end": 2665.68, "word": " أربع", "probability": 0.7775065104166666}, {"start": 2665.68, "end": 2665.94, "word": " مل", "probability": 0.98681640625}, {"start": 2665.94, "end": 2666.58, "word": " وبترك", "probability": 0.7342122395833334}, {"start": 2666.58, "end": 2667.04, "word": " الواحد", "probability": 0.96826171875}, {"start": 2667.04, "end": 2667.42, "word": " مل", "probability": 0.861328125}, {"start": 2667.42, "end": 2668.04, "word": " كما", "probability": 0.927734375}, {"start": 2668.04, "end": 2668.34, "word": " هو", "probability": 0.99755859375}, {"start": 2668.34, "end": 2668.78, "word": " و", "probability": 0.49560546875}, {"start": 2668.78, "end": 2668.92, "word": " هو", "probability": 0.68505859375}, {"start": 2668.92, "end": 2669.12, "word": " اللي", "probability": 0.962646484375}, {"start": 2669.12, "end": 2669.52, "word": " فيه", "probability": 0.933837890625}, {"start": 2669.52, "end": 2670.36, "word": " Target", "probability": 0.82373046875}, {"start": 2670.36, "end": 2671.56, "word": " إذا", "probability": 0.667236328125}, {"start": 2671.56, "end": 2671.84, "word": " الواحد", "probability": 0.9835611979166666}, {"start": 2671.84, "end": 2672.02, "word": " مل", "probability": 0.850341796875}, {"start": 2672.02, "end": 2672.46, "word": " الأخير", "probability": 0.8531901041666666}, {"start": 2672.46, "end": 2672.88, "word": " هو", "probability": 0.98095703125}, {"start": 2672.88, "end": 2673.1, "word": " اللي", "probability": 0.97900390625}, {"start": 2673.1, "end": 2673.52, "word": " فيه", "probability": 0.978759765625}, {"start": 2673.52, "end": 2674.4, "word": " Target", "probability": 0.90380859375}, {"start": 2674.4, "end": 2675.7, "word": " Spermatozoa", "probability": 0.749755859375}, {"start": 2675.7, "end": 2675.98, "word": " with", "probability": 0.82080078125}, {"start": 2675.98, "end": 2676.38, "word": " high", "probability": 0.591796875}, {"start": 2676.38, "end": 2676.94, "word": " quality", "probability": 0.7998046875}, {"start": 2676.94, "end": 2677.62, "word": " باخد", "probability": 0.8107096354166666}, {"start": 2677.62, "end": 2677.88, "word": " منها", "probability": 0.991455078125}, {"start": 2677.88, "end": 2678.22, "word": " عشرة", "probability": 0.8359375}, {"start": 2678.22, "end": 2678.5, "word": " micro", "probability": 0.41455078125}, {"start": 2678.5, "end": 2678.94, "word": " بعملها", "probability": 0.812744140625}, {"start": 2678.94, "end": 2679.4, "word": " evaluation", "probability": 0.71435546875}, {"start": 2679.4, "end": 2680.26, "word": " assessment", "probability": 0.441650390625}, {"start": 2680.26, "end": 2680.8, "word": " عشان", "probability": 0.96923828125}, {"start": 2680.8, "end": 2681.0, "word": " يشوف", "probability": 0.7635091145833334}, {"start": 2681.0, "end": 2681.32, "word": " كدهش", "probability": 0.80029296875}, {"start": 2681.32, "end": 2681.42, "word": " ال", "probability": 0.97412109375}, {"start": 2681.42, "end": 2681.6, "word": " total", "probability": 0.7265625}, {"start": 2681.6, "end": 2682.04, "word": " count", "probability": 0.91845703125}], "temperature": 1.0}, {"id": 98, "seek": 269927, "start": 2682.31, "end": 2699.27, "text": "كداش ال concentration، كداش ال motility، كداش ال progressiveotype، و كده بتكون العين جاهزة لل exit سنستكفي بهذا القدر ان شاء الله على أمل أن نلتقي في محاضرات مستقبلية تم تم في حفظ الوريعات", "tokens": [4117, 3215, 33599, 2423, 9856, 12399, 9122, 3215, 33599, 2423, 2184, 1140, 12399, 9122, 3215, 33599, 2423, 16131, 13108, 12399, 4032, 9122, 3215, 3224, 39894, 30544, 18863, 9957, 10874, 40294, 11622, 3660, 24976, 11043, 8608, 1863, 14851, 4117, 41185, 39627, 15730, 25062, 3215, 2288, 16472, 13412, 16606, 21984, 15844, 5551, 42213, 14739, 8717, 1211, 2655, 38436, 8978, 3714, 5016, 46958, 2288, 9307, 3714, 14851, 4587, 36150, 10632, 46811, 46811, 8978, 11331, 5172, 19913, 2423, 13063, 1829, 3615, 9307], "avg_logprob": -0.2569224774083005, "compression_ratio": 1.51, "no_speech_prob": 1.8477439880371094e-06, "words": [{"start": 2682.31, "end": 2682.69, "word": "كداش", "probability": 0.6664225260416666}, {"start": 2682.69, "end": 2682.81, "word": " ال", "probability": 0.974609375}, {"start": 2682.81, "end": 2683.75, "word": " concentration،", "probability": 0.37664794921875}, {"start": 2683.75, "end": 2684.27, "word": " كداش", "probability": 0.9729817708333334}, {"start": 2684.27, "end": 2684.41, "word": " ال", "probability": 0.98828125}, {"start": 2684.41, "end": 2685.23, "word": " motility،", "probability": 0.7432454427083334}, {"start": 2685.23, "end": 2685.55, "word": " كداش", "probability": 0.984375}, {"start": 2685.55, "end": 2685.67, "word": " ال", "probability": 0.9697265625}, {"start": 2685.67, "end": 2686.79, "word": " progressiveotype،", "probability": 0.50439453125}, {"start": 2686.79, "end": 2686.91, "word": " و", "probability": 0.5498046875}, {"start": 2686.91, "end": 2687.01, "word": " كده", "probability": 0.81103515625}, {"start": 2687.01, "end": 2687.33, "word": " بتكون", "probability": 0.88671875}, {"start": 2687.33, "end": 2687.71, "word": " العين", "probability": 0.91943359375}, {"start": 2687.71, "end": 2688.73, "word": " جاهزة", "probability": 0.9036865234375}, {"start": 2688.73, "end": 2689.39, "word": " لل", "probability": 0.26904296875}, {"start": 2689.39, "end": 2689.87, "word": " exit", "probability": 0.5029296875}, {"start": 2689.87, "end": 2691.65, "word": " سنستكفي", "probability": 0.9216796875}, {"start": 2691.65, "end": 2691.95, "word": " بهذا", "probability": 0.965087890625}, {"start": 2691.95, "end": 2692.35, "word": " القدر", "probability": 0.9889322916666666}, {"start": 2692.35, "end": 2692.53, "word": " ان", "probability": 0.5205078125}, {"start": 2692.53, "end": 2692.83, "word": " شاء", "probability": 0.972412109375}, {"start": 2692.83, "end": 2692.93, "word": " الله", "probability": 0.95654296875}, {"start": 2692.93, "end": 2693.33, "word": " على", "probability": 0.83056640625}, {"start": 2693.33, "end": 2693.69, "word": " أمل", "probability": 0.81494140625}, {"start": 2693.69, "end": 2694.17, "word": " أن", "probability": 0.5888671875}, {"start": 2694.17, "end": 2694.55, "word": " نلتقي", "probability": 0.9576416015625}, {"start": 2694.55, "end": 2694.73, "word": " في", "probability": 0.93798828125}, {"start": 2694.73, "end": 2695.45, "word": " محاضرات", "probability": 0.78505859375}, {"start": 2695.45, "end": 2696.41, "word": " مستقبلية", "probability": 0.9376953125}, {"start": 2696.41, "end": 2697.31, "word": " تم", "probability": 0.368408203125}, {"start": 2697.31, "end": 2697.55, "word": " تم", "probability": 0.65966796875}, {"start": 2697.55, "end": 2697.77, "word": " في", "probability": 0.96484375}, {"start": 2697.77, "end": 2698.09, "word": " حفظ", "probability": 0.9967447916666666}, {"start": 2698.09, "end": 2699.27, "word": " الوريعات", "probability": 0.7150390625}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2744.34325, "duration_after_vad": 2668.520624999991}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/9mspvrq6uv4_raw.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/9mspvrq6uv4_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..97cd2044a73726b074c8a4d8a408f9c1a2a6d19d
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/9mspvrq6uv4_raw.srt
@@ -0,0 +1,2596 @@
+1
+00:00:00,570 --> 00:00:04,290
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:04,290 --> 00:00:09,550
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا
+
+3
+00:00:09,550 --> 00:00:13,330
+الأعزاء نرجو من الله الكريم أن تكونوا جميعا بخير
+
+4
+00:00:13,330 --> 00:00:18,670
+وبصحة جيدة تحدثنا في المحاضرة السابقة عن فحص يعتبر
+
+5
+00:00:18,670 --> 00:00:22,550
+من أهم الفعوصات التي تستخدم في تقييم قدرة الرجل
+
+6
+00:00:22,550 --> 00:00:26,650
+على الإنجاب وهو فحص تحليل السائل المنوي تحت مصطلح
+
+7
+00:00:26,650 --> 00:00:31,760
+Seminal Analysis قررناخلال الحديث عن هذا الفحص عن
+
+8
+00:00:31,760 --> 00:00:37,540
+عدة معايير مهمة كالـ volume الـ pH الفسكوسيتي الـ
+
+9
+00:00:37,540 --> 00:00:41,540
+concentration الـ count الـ motility بأقسامها
+
+10
+00:00:41,540 --> 00:00:45,280
+متمثلة في الـ progressive motile الـ non
+
+11
+00:00:45,280 --> 00:00:48,120
+progressive motile الـ non motile spermatozoa
+
+12
+00:00:48,120 --> 00:00:51,820
+انتقلنا للحديث عن الـ morphology انتقلنا للحديث عن
+
+13
+00:00:51,820 --> 00:00:56,060
+بعض الفحوصات المتعلقة بنشاط الـ sperm زي الـ
+
+14
+00:00:56,060 --> 00:01:00,070
+fructose test هذه معظمها فحوصاتلها علاقة بالـ
+
+15
+00:01:00,070 --> 00:01:04,610
+Seminal Fluid جميعها يتم إجراءها و يتم إنجازها في
+
+16
+00:01:04,610 --> 00:01:09,990
+المختبر وبعضها لا يتم تطرق إليها مثل فحص الفرقتوز
+
+17
+00:01:09,990 --> 00:01:15,350
+على سبيل المثال اليوم سوف نتحدث عن موضوع جديد له
+
+18
+00:01:15,350 --> 00:01:19,930
+علاقة بالآلية المتبعة و الطرق المستخدمة لتحضير
+
+19
+00:01:19,930 --> 00:01:24,170
+عينة الساقل للحقن المجهري أو للتلقيح الصناعي
+
+20
+00:01:24,170 --> 00:01:30,490
+التقليدي المسمى باسمIVF In Vitro Fertilization
+
+21
+00:01:30,490 --> 00:01:36,590
+ولكن قبل أن نتحدث عن هذه الآليات وهذه الطرق التي
+
+22
+00:01:36,590 --> 00:01:40,890
+يمكن أن تستخدم من أجل تحضير عينة السائل دعونا
+
+23
+00:01:40,890 --> 00:01:45,750
+نتكلم عن مصالحات طبية مهمة جداً لها علاقة بالـ XY
+
+24
+00:01:45,750 --> 00:01:51,510
+ولها علاقة بالـ Seminal Fluid من أشهرها Aspermia
+
+25
+00:01:51,510 --> 00:01:56,170
+فالـ Aspermia معناها أنعدم وجود seminal fluid هذا
+
+26
+00:01:56,170 --> 00:02:00,350
+الرجل لا يستطيع أن يعمل ejaculation فبالتالي في
+
+27
+00:02:00,350 --> 00:02:03,390
+عنده seminal fluid ال volume الخاص فيه zero مافي
+
+28
+00:02:03,390 --> 00:02:07,770
+عنده seminal أو semen volume مافي عنده semen
+
+29
+00:02:07,770 --> 00:02:12,150
+volume so the definition of a spermia is no
+
+30
+00:02:12,150 --> 00:02:17,190
+seminal fluid وينطبق عليها مصطلحين hypospermia
+
+31
+00:02:17,190 --> 00:02:21,120
+وhyperspermiaالـ Hyper-Spermia زيادة في الـ volume
+
+32
+00:02:21,120 --> 00:02:26,660
+في الحجم بيتجاوز الـ 5.5 ملي لتر أما الـ Hypo
+
+33
+00:02:26,660 --> 00:02:31,780
+-Spermia نقصان في الـ volume لكي يكون أقل من 2 ملي
+
+34
+00:02:31,780 --> 00:02:35,240
+لتر لأننا اتفقنا أن الـ normal volume للـ seminal
+
+35
+00:02:35,240 --> 00:02:40,820
+fluid 2 ملي لتر فزيادته و نقصانه له مصطلح معين
+
+36
+00:02:40,820 --> 00:02:46,400
+يليه مصطلح مهم جدا و هو أكثر انتشارا هو عبارة عن
+
+37
+00:02:46,400 --> 00:02:50,530
+الـ Oligospermiaالـ Ologospermia معناها نقصان في
+
+38
+00:02:50,530 --> 00:02:54,410
+عدد الحيوانات المنوية في كل واحد مليليتر لكي تصل
+
+39
+00:02:54,410 --> 00:02:59,590
+إلى أقل من 20 مليون حيوان في المليلتر الواحد يليه
+
+40
+00:02:59,590 --> 00:03:04,150
+مصطلح مهم ويعتبر من المصطلحات الأكثر انتشارا و
+
+41
+00:03:04,150 --> 00:03:08,170
+الأهم وهي مصطلح الـ Azospermia فالـ Azospermia
+
+42
+00:03:08,170 --> 00:03:12,350
+معناها عدم وجود سبيرماتوزوة في الـ seminal fluid
+
+43
+00:03:12,350 --> 00:03:18,070
+so the leak of sperm in the semen جدش بتتمثلهذه
+
+44
+00:03:18,070 --> 00:03:23,390
+العملية وهذا المصطلح مصطلح الازوسبيرميا يمثل 2% أو
+
+45
+00:03:23,390 --> 00:03:29,170
+يتواجد بمعدل 2% من ال total males population يعني
+
+46
+00:03:29,170 --> 00:03:33,870
+بمعنى أخر كل 100 male وكل 100 men فيهم اتنين
+
+47
+00:03:33,870 --> 00:03:38,070
+مصابين بالازوسبيرميا أيضا وجدوا ان الازوسبيرميا
+
+48
+00:03:38,070 --> 00:03:43,490
+تتواجد بمعدل 10-15% من الذكور المشخصين بأنهم
+
+49
+00:03:43,490 --> 00:03:47,710
+infertile هذا المصطلح مصطلحمهم وخاطير في نفس
+
+50
+00:03:47,710 --> 00:03:51,790
+اللحظة خدوا بالك في مصطلحين انهم علاقة بال
+
+51
+00:03:51,790 --> 00:03:56,070
+asospermia asospermia as general term و asospermia
+
+52
+00:03:56,070 --> 00:04:02,230
+after centrifugation ال asospermia as general term
+
+53
+00:04:02,230 --> 00:04:05,490
+انه تكنولوجيست عامل scanning للشريحة مالجاش فيها
+
+54
+00:04:05,490 --> 00:04:08,410
+sperm وضع انه عدد ال sperm zero فبالتالي
+
+55
+00:04:08,410 --> 00:04:12,530
+asospermia في تكنولوجيست اخر و emperiologist اخر
+
+56
+00:04:12,530 --> 00:04:16,840
+اكتر ضراية بالعملفأخد العينة ك total sample وضعها
+
+57
+00:04:16,840 --> 00:04:19,960
+في test tube وعملها centrifugation أخد جزء من ال
+
+58
+00:04:19,960 --> 00:04:24,800
+sediment وعملها scanning ماوجد sperm فبسميه
+
+59
+00:04:24,800 --> 00:04:29,060
+aspermia after centrifugation وهو المصطلح الأدق
+
+60
+00:04:29,060 --> 00:04:32,960
+لأن ممكن أنا لما أعمل mixing و أخد 50 micro أو 10
+
+61
+00:04:32,960 --> 00:04:35,780
+micro و أعملها scanning ومالاجيش لو أنا عملت
+
+62
+00:04:35,780 --> 00:04:39,020
+mixing كويس أو عملت centrifugation للعينة يعني
+
+63
+00:04:39,020 --> 00:04:42,650
+جمعتها ورصبتها وعملت لها concentrationواخدت من الـ
+
+64
+00:04:42,650 --> 00:04:45,650
+sediments ممكن ألاقي sperm او اتنين او تلاتة لأن
+
+65
+00:04:45,650 --> 00:04:50,130
+هذا بيأثر على طبيعة علاج المريض فيما بعد فمهم جدا
+
+66
+00:04:50,130 --> 00:04:54,070
+بعد ما ألاقي مصطلح Azospermia في العينة و أعمل فحص
+
+67
+00:04:54,070 --> 00:04:56,930
+للعينة و ألاقيها Azospermia أعملها centrifugation
+
+68
+00:04:56,930 --> 00:05:00,710
+و أفحصها مرة تانية عشان أقول Azospermia after
+
+69
+00:05:00,710 --> 00:05:04,030
+centrifugation أو لجت واحد sperm after
+
+70
+00:05:04,030 --> 00:05:08,150
+centrifugation فهذا المصطلح مهم جداهنتكلم عنه لما
+
+71
+00:05:08,150 --> 00:05:11,310
+نصل إلى الـ testicular biopsy كيف المصطلح
+
+72
+00:05:11,310 --> 00:05:15,570
+الازوسبيرميا after centrifugation بلعب دور كبير
+
+73
+00:05:15,570 --> 00:05:20,830
+ومهم في تحديد هل هذا الذكر أو هذا الرجل يلجأ إلى
+
+74
+00:05:20,830 --> 00:05:24,310
+ال testicular biopsy أو لا وإن لجأ إلى ال
+
+75
+00:05:24,310 --> 00:05:27,450
+testicular biopsy ما طبيعة ال biopsy هنتكلم في
+
+76
+00:05:27,450 --> 00:05:31,810
+عيندي أربع أنواع أسبابها بشكل أساسي أسباب
+
+77
+00:05:31,810 --> 00:05:35,150
+الازوسبيرميا قد تكون ال blockage على طول ال
+
+78
+00:05:35,150 --> 00:05:38,280
+reproductive tractأو قد يكون عندي abnormality في
+
+79
+00:05:38,280 --> 00:05:41,700
+ال hormone level وأشهرهم in FSH and H-testosterone
+
+80
+00:05:41,700 --> 00:05:45,040
+قد يكون عندي مشكلة في ال ejaculatory duct قد يكون
+
+81
+00:05:45,040 --> 00:05:48,820
+عندي مشكلة أساسية وظيفية أو تركيبية في ال
+
+82
+00:05:48,820 --> 00:05:52,580
+testicular وال testicular أو ال testis هي المصنع
+
+83
+00:05:52,580 --> 00:05:57,620
+الأساسي لإنتاج الاسبيرميا وبناء على هذا تم تقسيم
+
+84
+00:05:57,620 --> 00:06:01,880
+الاسبيرميا إلى قسمين أساسيين obstructive aspermia
+
+85
+00:06:01,880 --> 00:06:07,400
+و non-obstructive aspermiaفطالما تم تقسيم الـ
+
+86
+00:06:07,400 --> 00:06:09,700
+Azospermia إلى Obstructive وNon-obstructive
+
+87
+00:06:09,700 --> 00:06:13,720
+Azospermia ما هو الفرق؟ ما هو الفرق بين الـ
+
+88
+00:06:13,720 --> 00:06:17,020
+Obstructive وNon-obstructive Azospermia؟ الـ
+
+89
+00:06:17,020 --> 00:06:21,620
+Obstructive Azospermia وجدوا أن أكثر أسباب توجودها
+
+90
+00:06:21,620 --> 00:06:26,560
+هي عبارة عن Blockage في الـ Vase Difference أو الـ
+
+91
+00:06:26,560 --> 00:06:29,780
+Epidermis أو الـ Ejaculatory Duct فقط Blockage؟ لأ
+
+92
+00:06:30,010 --> 00:06:33,150
+واجهته ممكن يكون سبب آخر إن الـ Congenital Absence
+
+93
+00:06:33,150 --> 00:06:37,190
+في الـ Vast Difference إبداد مصر وإيجاكلوتريدارت
+
+94
+00:06:37,190 --> 00:06:39,650
+تبشوفوا الفرق بين ال blockage و الcongenital
+
+95
+00:06:39,650 --> 00:06:43,270
+absence ال blockage إن هذا علم الذكر أو هذا الرجل
+
+96
+00:06:43,270 --> 00:06:46,990
+تعرض إلى حادث معين عمل وجود blockage وانسداد في
+
+97
+00:06:46,990 --> 00:06:50,170
+هذه القنوات المذكورة التلاتة أما الcongenital
+
+98
+00:06:50,170 --> 00:06:55,290
+absence .. absence .. absence وهو إن ال male خُلِق
+
+99
+00:06:55,290 --> 00:07:00,610
+وولد وجاء على قيد الحياة وماعندهش هدىالمُركّبات أو
+
+100
+00:07:00,610 --> 00:07:03,510
+واحد منهم ماعندهوش الـ Epidermis ماعندهوش ال vast
+
+101
+00:07:03,510 --> 00:07:06,630
+difference وماعندهوش ال ejaculatory duct وارد صحيح
+
+102
+00:07:06,630 --> 00:07:11,390
+وارد ماهي المشاكل والأسباب التي تؤدي إلى حدوث ال
+
+103
+00:07:11,390 --> 00:07:13,990
+blockage بشكل أساسي لأن ال blockage يُعتبر هو
+
+104
+00:07:13,990 --> 00:07:18,350
+الأكثر انتشارة من أشهر الأسباب في عندي trauma أو
+
+105
+00:07:18,350 --> 00:07:21,810
+injury في منطقة .. في منطقة خاصة بال reproductive
+
+106
+00:07:21,810 --> 00:07:26,650
+tract infection أو inflammation في عندي عملية
+
+107
+00:07:26,650 --> 00:07:29,680
+جراحية في منطقة ال pelvic areaفي عندي الـ
+
+108
+00:07:29,680 --> 00:07:32,800
+vasectomy وهو إن الـ vas deference تعرض للاستقصال
+
+109
+00:07:32,800 --> 00:07:39,700
+ذكر رجل مصاب بـ cystic fibrosis أو mutation في
+
+110
+00:07:39,700 --> 00:07:43,040
+الجين الخاص بالـ cystic fibrosis فهذا الـ mutation
+
+111
+00:07:43,040 --> 00:07:47,600
+أدى إلى حدوث مشكلة في الـ vas deference مما أدى
+
+112
+00:07:47,600 --> 00:07:51,400
+إلى وجود مشكلة في تطور الـ vas deference فأدى إلى
+
+113
+00:07:51,400 --> 00:07:56,100
+حدوث blockage في الـ vas deference بشكل أساسي إذن،
+
+114
+00:07:56,100 --> 00:07:59,770
+بناء على هذا الكلامفي أسباب معينة علاقة بالـ
+
+115
+00:07:59,770 --> 00:08:05,770
+Obstructive Azospermia وتطرقنا إليها بشكل و بآخر و
+
+116
+00:08:05,770 --> 00:08:08,010
+من أشهر اللي قلنا عنها هي الـ Blockage في الـ
+
+117
+00:08:08,010 --> 00:08:11,270
+Vasodifference اللي بتدمس و النوع التاني الـ
+
+118
+00:08:11,270 --> 00:08:14,730
+Ejaculatory duct واحد منهم أو التلاتة مع بعضنجي
+
+119
+00:08:14,730 --> 00:08:18,990
+للشق الأخر من أنواع الـ Azospermia اللي حكيناها
+
+120
+00:08:18,990 --> 00:08:22,430
+Non-obstructive Azospermia والمعصود بالـ Non
+
+121
+00:08:22,430 --> 00:08:26,690
+-obstructive Azospermia أن التلاتة المُركّبات
+
+122
+00:08:26,690 --> 00:08:29,710
+الأساسية أو التركيبات التلاتة الأساسية سواء كان
+
+123
+00:08:29,710 --> 00:08:31,950
+الـ Epidermis أو الـBase Difference أو
+
+124
+00:08:31,950 --> 00:08:35,250
+الـGeriatric Reduct بيكونوا سالمين 100% ما في
+
+125
+00:08:35,250 --> 00:08:40,720
+عندهم Blockage ولكن في أسباب أخرى عبارة عنأسباب
+
+126
+00:08:40,720 --> 00:08:48,560
+جانبية أدت إلى إنقاس معدل إنتاج الـ sperm فبالتالي
+
+127
+00:08:48,560 --> 00:08:51,260
+هذه الـ external factor أو الـ other factor هي
+
+128
+00:08:51,260 --> 00:08:56,140
+اللي أثرت على المصنع بشكل أساسي ولم تؤثر على عوامل
+
+129
+00:08:56,140 --> 00:09:00,040
+أخرى خلّينا نشوف إيش ممكن الأسباب التي تؤدي إلى
+
+130
+00:09:00,040 --> 00:09:03,520
+الـ non-obstructive azospermia الـ non-obstructive
+
+131
+00:09:03,520 --> 00:09:07,760
+azospermia المقصود فيها أن التلت تركيباتالأساسية
+
+132
+00:09:07,760 --> 00:09:11,120
+اللي اتكلمنا عليها Vas deferens Epidermis جاكولاتي
+
+133
+00:09:11,120 --> 00:09:15,320
+ردكت Normal there is no blockage in this tipule or
+
+134
+00:09:15,320 --> 00:09:19,160
+in this tract ولكن there is another external
+
+135
+00:09:19,160 --> 00:09:23,140
+factor أثرت على الـ testis بشكل أساسي منها الـ
+
+136
+00:09:23,140 --> 00:09:29,800
+genetic causes أسباب ورثية من أشعر الـ Klinefelter
+
+137
+00:09:29,800 --> 00:09:33,620
+والـ Klinefelter هو عبارة عن male with two copies
+
+138
+00:09:33,620 --> 00:09:38,270
+of X chromosome فهذا يؤدي إلىوجود ضمور في الـ
+
+139
+00:09:38,270 --> 00:09:41,230
+testis مما يؤدي إلى إنقاس معدّى لإنتاج الـ spermia
+
+140
+00:09:41,230 --> 00:09:44,750
+أيضًا من أسباب الوراثية التي تؤدي إلى non
+
+141
+00:09:44,750 --> 00:09:47,030
+-obstructive azospermia أو بشكل أساسي الـ
+
+142
+00:09:47,030 --> 00:09:50,570
+azospermia ولكن non-obstructive هي وجود micro
+
+143
+00:09:50,570 --> 00:09:53,710
+-deletion في الـ Y-Chromosome لأن الـ Y-Chromosome
+
+144
+00:09:53,710 --> 00:09:58,750
+يحتوي على جينات تلعب دورة مهمة وأساسية وحساسة في
+
+145
+00:09:58,750 --> 00:10:02,820
+إنتاج الحيوانات المنويةفلو صار microdilation في
+
+146
+00:10:02,820 --> 00:10:06,000
+الـY كرمز وملاجينات أساسية معناه لـ production
+
+147
+00:10:06,000 --> 00:10:10,560
+rate will be declined هرمون abnormality or
+
+148
+00:10:10,560 --> 00:10:14,820
+imbalance ومن أشهر هذه الحالات وجود ما يُعرف اسمه
+
+149
+00:10:14,820 --> 00:10:18,940
+الـ Hypogonadotropic Hypogonadotropic يعني نقصان
+
+150
+00:10:18,940 --> 00:10:22,700
+في مستوى الهرمونات التي تفرز من مناطق معينة الجناد
+
+151
+00:10:22,700 --> 00:10:27,240
+ومن أشهر هذه الهرمونات التستيستيرون الذي يلعب دورة
+
+152
+00:10:27,240 --> 00:10:33,090
+مهمة في إنتاج وتطور ومدوجالحيوانات المنوية أيضًا
+
+153
+00:10:33,090 --> 00:10:38,130
+Hypogonadism من حيث الـGonadism أيضًا من أشهر
+
+154
+00:10:38,130 --> 00:10:44,830
+الأسباب أيضًا Hyperprolactinemia
+
+155
+00:10:44,830 --> 00:10:49,650
+بمعنى آخر زيادة مستوى هرمون البرولاكتين زي ما
+
+156
+00:10:49,650 --> 00:10:52,810
+البرولاكتين بيعمل infertility مؤقت عند الفيميل
+
+157
+00:10:52,810 --> 00:10:56,310
+أيضًا البرولاكتين قد يؤدي ويعمل بشكل سلبي على
+
+158
+00:10:56,310 --> 00:11:00,070
+المادة فبالتالي لازم للبرولاكتين يصير فيه عنده
+
+159
+00:11:00,690 --> 00:11:04,390
+عملية معالجة في حالة ارتفاعه من أسباب الهرمونية
+
+160
+00:11:04,390 --> 00:11:07,890
+أيضًا الـ Androgen-resistant أنه في عندي Androgen
+
+161
+00:11:07,890 --> 00:11:11,590
+-hormone وفي عندي Sex-hormone ولكن الـ Receptor مش
+
+162
+00:11:11,590 --> 00:11:15,230
+شغال عشان تستقبله فبالتالي لا يؤد الوظيفة المقلوبة
+
+163
+00:11:15,230 --> 00:11:19,650
+فيه سبب تاني من أسباب الـ Azoospermia ولكن الـ Non
+
+164
+00:11:19,650 --> 00:11:23,250
+-obstructive Azoospermia سيرتولي سيل Only Syndrome
+
+165
+00:11:23,250 --> 00:11:26,990
+وهي عبارة عن مشكلة في السيرتولي السيل التي تلعب
+
+166
+00:11:26,990 --> 00:11:31,540
+دورة مهمة في تطور وانضاجالحيوانات المنوية
+
+167
+00:11:31,540 --> 00:11:38,220
+spermatogenic arrest تستكل failure to produce full
+
+168
+00:11:38,220 --> 00:11:43,180
+mature sperm cell انه تستشغالة ولكن في عندها ضعف
+
+169
+00:11:43,180 --> 00:11:46,780
+في منطقة معينة أو في مرحلة معينة من مراحل التطور
+
+170
+00:11:46,780 --> 00:11:50,600
+ونضوج الحيوانات المنوية فبالتالي بيعطيني sperm
+
+171
+00:11:50,600 --> 00:11:55,600
+ولكن هذا ال sperm لا يكون ناضج بالشكل المطلوب أو
+
+172
+00:11:55,600 --> 00:12:01,400
+بالكيفية المطلوبةسبب آخر من أسباب الـ azoospermia
+
+173
+00:12:01,400 --> 00:12:05,640
+ولكن الـ non-obstructive ال trauma ال radiation ال
+
+174
+00:12:05,640 --> 00:12:09,760
+varicosein أيضا كيدنفيريا ال diabetes .. ال
+
+175
+00:12:09,760 --> 00:12:13,480
+diabetic أو ال diabetes ال cirrhosis هذه كلها
+
+176
+00:12:13,480 --> 00:12:18,300
+تعتبر من الأسباب التي تؤدي وتساهم في حدود ال non
+
+177
+00:12:18,300 --> 00:12:20,740
+-obstructive azoospermia ال non-obstructive
+
+178
+00:12:20,740 --> 00:12:25,260
+azoospermia في مصطلح تاني من المصطلحات الطبية
+
+179
+00:12:25,260 --> 00:12:31,460
+المهمةas in to zoospermia وهذا المصطلح مقصود فيه
+
+180
+00:12:31,460 --> 00:12:36,880
+أنه فيها عندي ك technologist عندي عينات عينات هذه
+
+181
+00:12:36,880 --> 00:12:41,220
+فيها sperm motility أو sperm motile ولكن في عندي
+
+182
+00:12:41,220 --> 00:12:45,900
+reduction في كمية ونسبة الحيوانات المنوية المتحركة
+
+183
+00:12:45,900 --> 00:12:51,260
+حتى تصل إلى أقل من 40% ورغم أنه ال normal range ل
+
+184
+00:12:51,260 --> 00:12:57,430
+ال total motile 42% عفوا 40%بس لـ Progressive 32%
+
+185
+00:12:57,430 --> 00:13:00,210
+فبالتالي لو صار في عندي reduction in the
+
+186
+00:13:00,210 --> 00:13:05,390
+percentage of total sperm motile less than 40% هذا
+
+187
+00:13:05,390 --> 00:13:09,870
+المصطلح بسميه سينو ذي سبيرميا طب شو أسبابه؟ شو
+
+188
+00:13:09,870 --> 00:13:13,670
+العوامل الممكن تسبب و تأثر على ال sperm motility؟
+
+189
+00:13:13,670 --> 00:13:17,290
+في عندي عدة عوامل من أول عوامل التي تؤثر سلبا عن
+
+190
+00:13:17,290 --> 00:13:21,670
+ال sperm motility ال Vercosyl دوال الخصية اخدوا
+
+191
+00:13:21,670 --> 00:13:25,290
+بالك ال Vercosyl هو عبارة عن تضخم في بعض الأوردةأو
+
+192
+00:13:25,290 --> 00:13:30,690
+التي تحيط بالـ testes تعتبر reversible بمعنى آخر
+
+193
+00:13:30,690 --> 00:13:35,910
+إنه ممكن يصير علاج إلها و ترجع مرة تانية هذا يعتبر
+
+194
+00:13:35,910 --> 00:13:39,930
+مشكلة مؤقتة تزال بعملية جراحية في عندي مشكلة أيضًا
+
+195
+00:13:39,930 --> 00:13:43,710
+seminal tract infection في عندي antisperm antibody
+
+196
+00:13:43,710 --> 00:13:47,190
+لأن الـ antibody هيعمل قتل للـ sperm ويفقد قدرته
+
+197
+00:13:47,190 --> 00:13:51,310
+على حركة فيما بيعمل reduction poor nutrition عندي
+
+198
+00:13:51,310 --> 00:13:54,380
+مشكلة في التخزينةما عنده كمية كافية من ال fractose
+
+199
+00:13:54,380 --> 00:13:58,400
+ما بتناول فواكه بكمية كافرة ما بتناول مصادر ال
+
+200
+00:13:58,400 --> 00:14:01,980
+fractose فبالتالي هيفقد ال sperm قدرته على الحركة
+
+201
+00:14:01,980 --> 00:14:07,460
+بسبب فقدانه العنصر الأساسي للحركة ال smoking ال
+
+202
+00:14:07,460 --> 00:14:10,280
+alcohol intake ال caffeine ال tobacco consumption
+
+203
+00:14:10,280 --> 00:14:17,020
+هذا كلها تعتبر من أسباب التي تؤدي إلى نقصان مستوى
+
+204
+00:14:17,020 --> 00:14:23,560
+ونسبة حركة الحيوانات المنوية هذه بشكل أساسيمن
+
+205
+00:14:23,560 --> 00:14:28,060
+الأسباب الأخرى التي تساهم في نقصان معدل ونسبة تحرك
+
+206
+00:14:28,060 --> 00:14:31,840
+الحيوانات المنوية هو التعرض لبعض الـ toxic agents
+
+207
+00:14:31,840 --> 00:14:36,740
+زي الناس الـ farmers الناس اللي بتشتغل في البنزينة
+
+208
+00:14:36,740 --> 00:14:38,960
+الناس اللي بتشتغل كمزارعين الناس اللي بتشتغل في
+
+209
+00:14:38,960 --> 00:14:43,120
+مصنع البطاريات الناس اللي بتشتغل في المناجم الفحم
+
+210
+00:14:43,120 --> 00:14:46,820
+تتعرض لكمية كبيرة جدا من ال organic solvent أو
+
+211
+00:14:46,820 --> 00:14:51,470
+المواد التي تعتبر مواد سامةالمشكلة ليست في التعرض،
+
+212
+00:14:51,470 --> 00:14:54,030
+المشكلة في كمية التعرض ووقت التعرض و ال
+
+213
+00:14:54,030 --> 00:14:56,350
+concentration اللي بتتعرض إليه الإنسان يعني ممكن
+
+214
+00:14:56,350 --> 00:14:59,250
+أي إنس إحنا في حياتنا اليوم دي متتعرض ولكن جنتيش
+
+215
+00:14:59,250 --> 00:15:01,910
+متتعرض، أنت ممكن تتعرض ساعة، من إزاي اللي بيشتغل
+
+216
+00:15:01,910 --> 00:15:04,870
+في البنزينة بدوام 12 ساعة؟ ومش اللي بيشتغل في
+
+217
+00:15:04,870 --> 00:15:09,110
+الفحم و في منجم الفحم بدوام ممكن يصل إلى 24 ساعة،
+
+218
+00:15:09,110 --> 00:15:12,710
+متواصل أو متقطع فبالتالي في عنده duration لل
+
+219
+00:15:12,710 --> 00:15:18,750
+exposure كمية، توقت عالي جدا، فبيعمل مشاكل في ال
+
+220
+00:15:18,750 --> 00:15:22,970
+spare motilityأيضًا الـ Age بيلعب دور عكسي في
+
+221
+00:15:22,970 --> 00:15:29,390
+وجهية الدراسات أن هناك علاقة سلبية ما بين الـ Age
+
+222
+00:15:29,390 --> 00:15:34,870
+و percentage of sperm motility تحت مصطلح Negative
+
+223
+00:15:34,870 --> 00:15:37,690
+Correlation between the Male Age and the
+
+224
+00:15:37,690 --> 00:15:41,130
+Percentage of Sperm Motile كل ما زاد ال Age قل
+
+225
+00:15:41,130 --> 00:15:44,510
+الموتلتي كل ما قل ال Age زاد الموتالي ال sperm
+
+226
+00:15:44,510 --> 00:15:48,170
+أيضًا ال Cancer بيلعب دور سلبي لأنه طول ما في عندي
+
+227
+00:15:48,170 --> 00:15:50,540
+Cancerفي عند الـ Radiotherapy، في عند الـ
+
+228
+00:15:50,540 --> 00:15:55,000
+Chemotherapy وكلهم يؤثر سلبًا على مصنع الحيوانات
+
+229
+00:15:55,000 --> 00:15:57,980
+المنوية وفيأثر سلبًا على الحيوانات المنوية
+
+230
+00:15:57,980 --> 00:16:00,600
+الموجودة في الـ edited mass ويؤثر سلبًا على
+
+231
+00:16:00,600 --> 00:16:04,740
+الحيوانات المنوية التي ما زالت تُخلق فبالتالي، دي
+
+232
+00:16:04,740 --> 00:16:09,180
+بيعمل reduction عندى في عدد ال sperm المتحارب في
+
+233
+00:16:09,180 --> 00:16:13,540
+عنده مصطلح آخر اسمه Teratospermia ما المقصود بهذا
+
+234
+00:16:13,540 --> 00:16:18,320
+المصطلح Teratospermia معناه إن في أنا عند spermفي
+
+235
+00:16:18,320 --> 00:16:22,980
+عندى spermatozoa وفي عندى mature sperm ولكن معدل
+
+236
+00:16:22,980 --> 00:16:28,560
+ال .. او نسبة .. نسبة ال sperm اللى يعتبر up
+
+237
+00:16:28,560 --> 00:16:32,360
+normal form عالى جدا up normal form يعني ميجارو
+
+238
+00:16:32,360 --> 00:16:36,060
+head، pen head، double tail، two mid piece يعني
+
+239
+00:16:36,060 --> 00:16:40,440
+بمعنى اخر انا عملت scanning للعينة لجيت عدد ومستوى
+
+240
+00:16:40,440 --> 00:16:44,240
+ونسبة ومعدل تواجد ال up normal form spermatozoa
+
+241
+00:16:44,240 --> 00:16:49,850
+عالى جدابالتالي بسميها Teratospermia Teratospermia
+
+242
+00:16:49,850 --> 00:16:53,530
+شو أسبابها؟ شو ال most common؟ شو الفكرة التي تؤدي
+
+243
+00:16:53,530 --> 00:16:58,010
+إلى حدوث Teratospermia؟ أول حاجة ال infection ال
+
+244
+00:16:58,010 --> 00:17:01,650
+chronic infection كل ما اتعرضت أو حنعرف إيش عن ال
+
+245
+00:17:01,650 --> 00:17:05,250
+chronic infection أو كيف ال chronic infection بسبب
+
+246
+00:17:05,250 --> 00:17:09,790
+تغيب في أشكال الحيوانات خدوا بالكوا أربطوها و
+
+247
+00:17:09,790 --> 00:17:12,770
+هنتكلم عنها بشكل مستفيد تكلمنا عن المحاضرة الفاتتة
+
+248
+00:17:13,100 --> 00:17:15,660
+Coronic infection يعني ال immune system هيشتغل
+
+249
+00:17:15,660 --> 00:17:19,560
+يعني في عندي white pieces هتهاجل للمنطقة هذه هتفرز
+
+250
+00:17:19,560 --> 00:17:22,720
+ال white pieces كمية كبيرة جدا من ال free radical
+
+251
+00:17:22,720 --> 00:17:27,380
+فتديني ROS Reactive Oxygen Species هذي بتعملي
+
+252
+00:17:27,380 --> 00:17:30,780
+degradation في ال DNA و في المorphology بتاعة ال
+
+253
+00:17:30,780 --> 00:17:35,040
+sperm ببساطة جدا Smoking و ال alcohol intake تؤدي
+
+254
+00:17:35,040 --> 00:17:39,600
+إلى Teratospermia عدم وجود اتزان و تناور طعام صحي
+
+255
+00:17:39,600 --> 00:17:43,250
+تؤدي إلى Teratospermiaالـ Obesity تعتبر من أهم
+
+256
+00:17:43,250 --> 00:17:46,730
+العوامل التي تساعد في وجود Teratospermia الـ Drug
+
+257
+00:17:46,730 --> 00:17:51,830
+الذي يتم تناوله بغير وصفة طبية أو بغير جرعة طبية
+
+258
+00:17:51,830 --> 00:17:55,210
+بعض الأدوية تؤثر سلبة أيضًا وجود ال trauma في
+
+259
+00:17:55,210 --> 00:17:59,610
+منطقة ال testicular تؤثر على ال morphology الخاص
+
+260
+00:17:59,610 --> 00:18:04,870
+بالـ spermatozoa كل هذه المصطلحات وكل هذه الأسباب
+
+261
+00:18:04,870 --> 00:18:09,990
+تؤدي إلى حدوث مشاكل في عملية إنتاجأو تطور أو مدوج
+
+262
+00:18:09,990 --> 00:18:14,730
+الـ spermatozoa مصطلح آخر بنسميه polyospermia
+
+263
+00:18:14,730 --> 00:18:20,710
+polyospermia وهو عبارة عن مصطلح المقصود فيه زيادة
+
+264
+00:18:20,710 --> 00:18:25,490
+عدد الحيوانات المنوية في السائل لتصل إلى أكثر من
+
+265
+00:18:25,490 --> 00:18:29,850
+200 مليون خلية أو 200 مليون sperm per milliliter
+
+266
+00:18:29,850 --> 00:18:34,450
+increase in the total number of spermatozoa to
+
+267
+00:18:34,450 --> 00:18:39,550
+arrive 200 million per milliliterطبعا هذا العدد
+
+268
+00:18:39,550 --> 00:18:43,670
+مهول يعتبر ومش كل زيادة في العدد تعتبر زيادة
+
+269
+00:18:43,670 --> 00:18:48,170
+إيجابية فبالتالي الزيادة قد تكون سلبية ببساطة جدا
+
+270
+00:18:48,170 --> 00:18:51,870
+تصور أن أنت عندك كمية كبيرة جدا قد كل المدرسة أو
+
+271
+00:18:51,870 --> 00:18:56,130
+كل الجامعة في حالة من حالات التصقيد سوف تخرج من
+
+272
+00:18:56,130 --> 00:19:00,730
+بوابة صغيرة جدا سوف يحدث تدافع عند عملية الخروج
+
+273
+00:19:00,730 --> 00:19:05,970
+مما يؤدي إلى وجود إصابات وقد يؤدي إلى اختناقات على
+
+274
+00:19:05,970 --> 00:19:10,640
+صعيد بسيط جداعلى الوضع الحالي فمباناك لو كان عندك
+
+275
+00:19:10,640 --> 00:19:17,340
+200 مليون sperm هيخرجوه بشكل دفقات متتالية هيصير
+
+276
+00:19:17,340 --> 00:19:21,240
+في اندي نوع من أنواع إعاقة في الحركة إعاقة في
+
+277
+00:19:21,240 --> 00:19:26,340
+الحركة يعني تدمير يعني ال fertility chance حدجه و
+
+278
+00:19:26,340 --> 00:19:30,420
+حدجيه عند المال طبعا it is usually associated with
+
+279
+00:19:30,420 --> 00:19:33,940
+a decrease in the volume of ejaculatory matter هذا
+
+280
+00:19:33,940 --> 00:19:37,390
+السبب اللي بيؤدي إلى زيادة الحجز زيادة العددإن ال
+
+281
+00:19:37,390 --> 00:19:40,210
+volume بدل ما يكون خمسة فيهم 200 مليون كان فيها
+
+282
+00:19:40,210 --> 00:19:45,090
+واحد مل فيهم 200 مليون فمن أهم أسباب زيادة ال
+
+283
+00:19:45,090 --> 00:19:49,330
+concentration of sperm أو دعنا نسميها زيادة ال
+
+284
+00:19:49,330 --> 00:19:52,330
+count of sperm هو عبارة عن حدوث reduction في ال
+
+285
+00:19:52,330 --> 00:19:55,730
+sperm volume في ال seminal volume it may be a
+
+286
+00:19:55,730 --> 00:19:59,610
+cause of infertility since such high concentration
+
+287
+00:19:59,610 --> 00:20:03,250
+can be difficult to their movement طبعا زيادة في
+
+288
+00:20:03,250 --> 00:20:08,670
+العدديودى الى تزاحم أثناء المسير في رحلة ال
+
+289
+00:20:08,670 --> 00:20:13,450
+fertilization فالتزاحم هذا هيكون تزاحم عكسى فهيمنع
+
+290
+00:20:13,450 --> 00:20:17,030
+من حركة ال despair ما تزوى بشكل المطلوب و بشكل
+
+291
+00:20:17,030 --> 00:20:22,970
+المناسب لأن فيه تدافع طبعا it is important
+
+292
+00:20:22,970 --> 00:20:26,710
+condition in male fertility because white cell
+
+293
+00:20:26,710 --> 00:20:30,790
+weak in the sperm and can't damage its genetic
+
+294
+00:20:30,790 --> 00:20:38,690
+material طبعا أيضا من أهم المصطلحاتوجود بعض ال
+
+295
+00:20:38,690 --> 00:20:43,790
+white pieces تؤثر سلبًا على هذه العملية طبعًا وجود
+
+296
+00:20:43,790 --> 00:20:47,970
+ال white pieces لها علاقة بحاجة بتسميها
+
+297
+00:20:47,970 --> 00:20:52,250
+Pyrospermia أو حاجة بتسميها present of leukocyte
+
+298
+00:20:52,250 --> 00:20:56,230
+in seminal fluid طبعًا وجود ال leukocyte في ال
+
+299
+00:20:56,230 --> 00:21:00,190
+seminal fluid معناه أنه في عندى infection ال
+
+300
+00:21:00,190 --> 00:21:03,230
+infection هيهاجر كمية كبيرة جدًا من ال white
+
+301
+00:21:03,230 --> 00:21:05,470
+pieces لدى المكان فبالتالي هيعملها destruction
+
+302
+00:21:06,450 --> 00:21:10,990
+ببساطة جدا وجود ال white pieces هيعمل رُس رُس
+
+303
+00:21:10,990 --> 00:21:15,870
+هيعمل destruction لgenetic material فيؤدي إلى فشل
+
+304
+00:21:15,870 --> 00:21:21,870
+ال sperm في قدرته على عملية الإخصاب while the
+
+305
+00:21:21,870 --> 00:21:24,170
+blood cell released powerful substance called
+
+306
+00:21:24,170 --> 00:21:27,430
+reactive oxygen species which destroy organism
+
+307
+00:21:27,430 --> 00:21:32,650
+that cause infection unfortunately أو للأسف بشكل
+
+308
+00:21:32,650 --> 00:21:38,540
+كبير جداوجدوا إن الرُس بتأثر سلبًا بشكل كبير جدًا
+
+309
+00:21:38,540 --> 00:21:42,260
+على الـ sperm DNA على الـ sperm motility وعلى الـ
+
+310
+00:21:42,260 --> 00:21:45,280
+sperm movement طبعًا فادوا بالكواخر تلت نقاط اللي
+
+311
+00:21:45,280 --> 00:21:49,540
+لهم علاقة بمصطلح وجود حاجة بنتسميها leukospermia
+
+312
+00:21:49,540 --> 00:21:53,260
+وليكوسبيرميا بيسموها وجود الـ leukocyte بكميات
+
+313
+00:21:53,260 --> 00:21:57,740
+كبيرة جدًا في الـ seminal fluid هذه رقم تلاتة
+
+314
+00:21:57,740 --> 00:22:01,560
+النقطة رقم تلاتة ونقطة رقم أربع ونقطة رقم خامسة
+
+315
+00:22:01,560 --> 00:22:05,140
+إلها علاقة بمصطلح اسمه leukospermia أو Pyrospermia
+
+316
+00:22:05,660 --> 00:22:08,740
+وهذا المصطلح Leukospermia أو Pyrospermia هي عبارة
+
+317
+00:22:08,740 --> 00:22:12,240
+عن present of leukocyte in seminal fluid with high
+
+318
+00:22:12,240 --> 00:22:19,120
+number طبعا هذه المفروض في هنا عنوان جديد خلصنا من
+
+319
+00:22:19,120 --> 00:22:23,120
+المصطلحات التطبيقية المهمة سننتقل إلى موضوع جديد
+
+320
+00:22:23,120 --> 00:22:28,780
+كيف يتم تحضير عينات السائل من أجل ال ART أو ال X
+
+321
+00:22:28,780 --> 00:22:36,070
+أحد تقنيات ال ART طبعا في البداية في عندي مصطلحالـ
+
+322
+00:22:36,070 --> 00:22:39,630
+IVF In Vitro Fertilization فيها عند مصطلح الـ IGSI
+
+323
+00:22:39,630 --> 00:22:43,550
+وفيها عند مصطلح ال IUI إيش يعني ال IUI اختصارها
+
+324
+00:22:43,550 --> 00:22:49,650
+Intrauterine Insemination وهي ببساطة جدا هي إيصال
+
+325
+00:22:49,650 --> 00:22:56,510
+لـ spermatozoa الناضجة إلى الرحم
+
+326
+00:22:56,510 --> 00:23:03,930
+متى بنستخدمها إذا كان في مواجهة عنيفةمن قبل الـ
+
+327
+00:23:03,930 --> 00:23:06,970
+Female Piers الموجودة في منطقة الـ cervic ومنطقة
+
+328
+00:23:06,970 --> 00:23:11,130
+الفيجاينة لـ spermatozoa أو ال spermatozoa لا تقدر
+
+329
+00:23:11,130 --> 00:23:15,010
+تقطع هذه المسافة فبيجي الطبيب بياخد ال spermatozoa
+
+330
+00:23:15,010 --> 00:23:17,550
+بيعملها preparation بيحطها في انبوبة اسمها
+
+331
+00:23:17,550 --> 00:23:21,270
+catheter tube very thin و بيحطنها داخل الفاجاينة
+
+332
+00:23:21,270 --> 00:23:24,890
+الخاصة بالفيميل أو ببعناء آخر داخل الرحم الخاص
+
+333
+00:23:24,890 --> 00:23:28,690
+بالفيميل مرورا بالفاجاينة و السيرفيكال فبيقصر
+
+334
+00:23:28,690 --> 00:23:33,240
+المسافة اللي هتمشيها ال spermatozoa و بيقصروبيقلل
+
+335
+00:23:33,240 --> 00:23:35,980
+معدل الأخطار اللي بتوجهها الـ spermatozoa هذا
+
+336
+00:23:35,980 --> 00:23:41,100
+المصطلح بنسميه IUI intrauterine insemination يعني
+
+337
+00:23:41,100 --> 00:23:45,780
+الحقن داخل الرحم طبعا هذه بنعملها إذا كان الفيمايل
+
+338
+00:23:45,780 --> 00:23:49,580
+قبيعية 100% ولكن في عندى مشكلة في ال motility
+
+339
+00:23:49,580 --> 00:23:56,360
+الخاصة بال male spermatozoa شو السبب منها؟ شو
+
+340
+00:23:56,360 --> 00:24:00,700
+الهدف منها؟ تقليلالمصاعب والمخاطر اللي يتواجهها
+
+341
+00:24:00,700 --> 00:24:05,340
+الـ spermatozoa خلال رحلة ال fertilization في
+
+342
+00:24:05,340 --> 00:24:08,700
+منطقة ال cervical أو منطقة الفاجينة مرتبطة على الـ
+
+343
+00:24:08,700 --> 00:24:14,920
+leukocyte و الـ antisperm antibody و خلافه طيب ال
+
+344
+00:24:14,920 --> 00:24:20,440
+sperm process for IVF كيف يتم تحضير العينة؟ أو
+
+345
+00:24:20,440 --> 00:24:24,210
+خلال عملية تحضير العينة، شو بيصير؟طبعا خلال .. أو
+
+346
+00:24:24,210 --> 00:24:27,250
+فكرة تحضير العينة و الفكرة الأساسية للتحضير العينة
+
+347
+00:24:27,250 --> 00:24:31,010
+ومبدأ تحضير العينة يقوم على مبدأ أساسي هو عزل
+
+348
+00:24:31,010 --> 00:24:35,370
+الحيوانات المنوية الجيدة التي تعتبر normal form و
+
+349
+00:24:35,370 --> 00:24:38,690
+good motile فبالتالي طالما في عندي عزل للحيوانات
+
+350
+00:24:38,690 --> 00:24:42,130
+المنوية الجيدة إذا سوف يتم التخلص من ال similar
+
+351
+00:24:42,130 --> 00:24:47,830
+fluid أو ال similar plasma يتم التخلص من خلالها من
+
+352
+00:24:47,830 --> 00:24:50,790
+العوامل التي تعمل decapacitation والمقصود بال
+
+353
+00:24:50,790 --> 00:24:53,880
+decapacitationيعني فقدان الحيوانة المنوية القدرة
+
+354
+00:24:53,880 --> 00:24:59,920
+على الإخصاب إبعاد وعزل الـ dysfunctional والرُس
+
+355
+00:24:59,920 --> 00:25:05,680
+producing sperm بمعنى آخر إبعاد الـ sperm بـ
+
+356
+00:25:05,680 --> 00:25:09,340
+dysfunction اللي ممكن يفرس كمية كبيرة جدا من الرُس
+
+357
+00:25:09,340 --> 00:25:13,460
+اللي بتدمر الحيوانات المنوية الأخرى التخلص من الـ
+
+358
+00:25:13,460 --> 00:25:16,980
+leukocyte لأن الـ leukocyte جالب شوية حكينا ممكن
+
+359
+00:25:16,980 --> 00:25:22,580
+تفرس كمية كبيرة جدا من الرُس التخلص من البكتيريامن
+
+360
+00:25:22,580 --> 00:25:26,720
+أن البكتيريا تلعب سلبًا ودورًا سلبيًا على
+
+361
+00:25:26,720 --> 00:25:31,940
+الحيوانات المنوية المتبقية وتحسين قدرة الـ sperm
+
+362
+00:25:31,940 --> 00:25:36,000
+من حيث الحركة والمحافظة على المادة الوراثية بالشكل
+
+363
+00:25:36,000 --> 00:25:39,040
+الكامل بالإضافة إلى المحافظة على الـ Acrosome
+
+364
+00:25:39,040 --> 00:25:41,780
+Reaction والمحافظة على الـ sperm في حالة Normal
+
+365
+00:25:41,780 --> 00:25:47,580
+Form إذن هذه الخمس نقاط، خمس نقاط أساسية تحدث خلال
+
+366
+00:25:47,580 --> 00:25:51,720
+عملية الـ Sperm Processing for IVF-CorIgZ من أجلها
+
+367
+00:25:51,920 --> 00:25:54,900
+يتم المحافظة على الـ sperm يتم المحافظة على الـ
+
+368
+00:25:54,900 --> 00:25:57,780
+sperm و الـ acrosome .. sperm morphology و الـ
+
+369
+00:25:57,780 --> 00:26:01,580
+acrosome reaction و الـ motility الخاصة بالـ sperm
+
+370
+00:26:01,580 --> 00:26:05,580
+كيف يتم المحافظة على هذه الأمور؟ من خلال التخلص من
+
+371
+00:26:05,580 --> 00:26:08,520
+الحيوانات المنوية الميتة التخلص من البكتيريا
+
+372
+00:26:08,520 --> 00:26:12,100
+التخلص من الكورات الدم البيضاء و التخلص من الـ
+
+373
+00:26:12,100 --> 00:26:15,600
+seminal plasma التي قد تحتوي على الـ ant sperm
+
+374
+00:26:15,600 --> 00:26:20,200
+antibody أو إذا كان طبعاً للملاي يصنع antibody ضد
+
+375
+00:26:20,200 --> 00:26:25,070
+نفسهأو يحتوي على الـ Decapitation Factor هذه أهم
+
+376
+00:26:25,070 --> 00:26:30,750
+خمسة نقاط أساسية أهم خمسة نقاط أساسية ما هي الطرق
+
+377
+00:26:30,750 --> 00:26:34,130
+التي تستخدم في عملية ال isolation أول طريقة تستخدم
+
+378
+00:26:34,130 --> 00:26:36,750
+في عملية ال isolation و ال extraction و ال
+
+379
+00:26:36,750 --> 00:26:41,770
+processing هي طريقة بسيطة جدا تسمى simple dilution
+
+380
+00:26:41,770 --> 00:26:45,190
+and washing simple dilution and washing هنتكلم
+
+381
+00:26:45,190 --> 00:26:48,490
+عنها بالتفصيل النقطة التانية أو الطريقة التانية هي
+
+382
+00:26:48,490 --> 00:26:53,710
+ال swarm up و من اسمهاسباحة للأعلى النقطة التالتة
+
+383
+00:26:53,710 --> 00:26:57,510
+و الطريقة التالتة هي density أو density gradient
+
+384
+00:26:57,510 --> 00:27:01,510
+centrifugation density gradient gradient
+
+385
+00:27:01,510 --> 00:27:06,870
+centrifugation بمعنى آخر الفصل بناء على الكثافة
+
+386
+00:27:06,870 --> 00:27:11,270
+المتدرجة في عندي simple dilution and washing في
+
+387
+00:27:11,270 --> 00:27:14,650
+عندي sperm swarm up في عندي density gradient
+
+388
+00:27:14,650 --> 00:27:18,420
+centrifugationطبعا هذه التلت نقاط أو التلت عوامل
+
+389
+00:27:18,420 --> 00:27:22,960
+أو التلت طرق ان صح التعبير الأكثر استخداما والأكثر
+
+390
+00:27:22,960 --> 00:27:27,080
+شيوعا ولكن حاليا الأكثر استخداما الطريقة التانية
+
+391
+00:27:27,080 --> 00:27:30,960
+أو التالتة والأكثر على الإطلاق والأكثر استخداما في
+
+392
+00:27:30,960 --> 00:27:34,060
+مختبرات ال IWF هي الطريقة التالتة اللي لها علاقة
+
+393
+00:27:34,060 --> 00:27:37,700
+بال credit خلينا ناخد الطريقة الأولى اللي اسمها
+
+394
+00:27:37,700 --> 00:27:42,010
+simple dilution and washingببساطة جدًا خلال هذه
+
+395
+00:27:42,010 --> 00:27:45,550
+العملية يتم فصل الـ spermatozoa عن الـ seminal
+
+396
+00:27:45,550 --> 00:27:49,810
+fluid بما يحتويه فصل ال spermatozoa عن ال seminal
+
+397
+00:27:49,810 --> 00:27:55,130
+fluid بما يحتويه هذا البرنامج يحفظ قدرة البرنامج
+
+398
+00:27:55,130 --> 00:27:58,910
+للتواصل بشكل كبير بما يحتوي على البرنامج بما يحتوي
+
+399
+00:27:58,910 --> 00:28:01,110
+على البرنامج بما يحتوي على البرنامج بما يحتوي على
+
+400
+00:28:01,110 --> 00:28:02,530
+البرنامج بما يحتوي على البرنامج بما يحتوي على
+
+401
+00:28:02,530 --> 00:28:05,310
+البرنامج بما يحتوي على البرنامج بما يحتوي على
+
+402
+00:28:05,310 --> 00:28:06,170
+البرنامج بما يحتوي على البرنامج بما يحتوي على
+
+403
+00:28:06,170 --> 00:28:08,210
+البرنامج بما يحتوي على البرنامج بما يحتوي على
+
+404
+00:28:08,210 --> 00:28:11,770
+البرنامج بما يحتوي على الهذه الطريقة الأولى، يعني
+
+405
+00:28:11,770 --> 00:28:16,430
+أكثر .. أو أكثر الحالات التي يستخدم معها الطريقة
+
+406
+00:28:16,430 --> 00:28:19,050
+الأولى الـ simple dilution and washing مثل .. إذا
+
+407
+00:28:19,050 --> 00:28:23,570
+كان في عندي immune disorder إذا كان في عندي male
+
+408
+00:28:23,570 --> 00:28:30,590
+factor أو حالات عدم إنجاب غير معروفة السبب طبعا
+
+409
+00:28:30,590 --> 00:28:33,070
+هذا ال .. هذا ال technique بيحتاج dilution و
+
+410
+00:28:33,070 --> 00:28:37,270
+centrifugation طبعا ال sperm بيصير له washing ب
+
+411
+00:28:37,270 --> 00:28:40,370
+solution يحتوي على ال antibioticوبعض الـ
+
+412
+00:28:40,370 --> 00:28:44,390
+Supplemental Protein ومن أشهرهم الـ albumin يُضاف
+
+413
+00:28:44,390 --> 00:28:47,530
+يعني كإن أنا بستخدم media هذه ال media فيها
+
+414
+00:28:47,530 --> 00:28:52,210
+Antibiotic plus Supplemental Protein like albumin
+
+415
+00:28:52,210 --> 00:28:56,890
+بضيفها على عينة السمن بمعدل 1 إلى 1، 2 إلى 2
+
+416
+00:28:56,890 --> 00:29:00,350
+وخلافه ولكن الأكثر استخدام من ال ratio one to one
+
+417
+00:29:00,350 --> 00:29:05,590
+ال media sterile of the equal volume from the
+
+418
+00:29:05,590 --> 00:29:07,970
+seminal fluid يعني ال ratio ما بين ال media
+
+419
+00:29:07,970 --> 00:29:10,930
+المستخدمةالتي تحتوى على الـ Supplement Protein و
+
+420
+00:29:10,930 --> 00:29:15,330
+الـ Antibiotic إلى كمية السمن الفلويد لازم تكون 1
+
+421
+00:29:15,330 --> 00:29:19,690
+ل 1 بمعنى انا اضفت او بدي اعمل Washing ل 1ml من
+
+422
+00:29:19,690 --> 00:29:23,590
+العينة بدي اضيف 1ml من الـ Sample فباتشي بعمل
+
+423
+00:29:23,590 --> 00:29:26,770
+Mixing للعينة و بقيس كده عندى ال volume تدريجى
+
+424
+00:29:26,770 --> 00:29:30,400
+عندى 5mlإذا لازم أضيف عليهم خمسة mil من ال media
+
+425
+00:29:30,400 --> 00:29:34,220
+بعملها good mixing بعدين بضيفها في test tube و
+
+426
+00:29:34,220 --> 00:29:38,140
+بعملها centrifugation ع باستخدام طبعا ال
+
+427
+00:29:38,140 --> 00:29:42,300
+centrifuge طبعا ال centrifugation لها زمن معين و
+
+428
+00:29:42,300 --> 00:29:46,760
+سرعة معينة فبعملها centrifugation على تلاتمية دورة
+
+429
+00:29:46,760 --> 00:29:52,840
+300G لمدة عشر دقائق فهتفصلن مركبين أو طبقتين ال
+
+430
+00:29:52,840 --> 00:29:55,560
+cinnamon في الأسفل و ال supernatant كلها في الأعلى
+
+431
+00:29:56,430 --> 00:30:00,630
+removing with sterile pipet طبعا هنا for 10 minute
+
+432
+00:30:00,630 --> 00:30:04,310
+and then the supernatant is very careful remove
+
+433
+00:30:04,310 --> 00:30:08,630
+طبعا ال supernatant أنا مابديه لإنه فيه كل ال
+
+434
+00:30:08,630 --> 00:30:12,410
+depressed فيه كل ال decomposition factor فيه كل
+
+435
+00:30:12,410 --> 00:30:17,010
+العوامل اللي ممكن تأثر سلبا على ال sperm فبعمل
+
+436
+00:30:17,010 --> 00:30:21,530
+removing لل supernatant بسحبه بال sterile pipet او
+
+437
+00:30:21,530 --> 00:30:25,030
+ال dropper و برميهالـ Palette أو الـ Sediment
+
+438
+00:30:25,030 --> 00:30:28,230
+الموجود بعملها Resuspension و بضيف عليها بعد كده
+
+439
+00:30:28,230 --> 00:30:31,610
+واحد ملي من نفس ال media و بعملها Mixing و
+
+440
+00:30:31,610 --> 00:30:35,810
+Centrifugation لمدة خمس دقائق على نفس السرعة 300G
+
+441
+00:30:35,810 --> 00:30:39,110
+برفع ال supernatant و برميه بتخلص منه و بعمله
+
+442
+00:30:39,110 --> 00:30:42,910
+discard بعد كده بعمل Resuspension لل Palette و
+
+443
+00:30:42,910 --> 00:30:46,010
+بضيف عليها واحد مل من نفس ال media أنا كده بكون
+
+444
+00:30:46,010 --> 00:30:49,410
+غسلتها مرتين ممكن أغسلها كمان مرة مافيش مشكلة بضيف
+
+445
+00:30:49,410 --> 00:30:53,140
+واحد مل مرة تانيةmixing centrifugation على 300G
+
+446
+00:30:53,140 --> 00:30:57,580
+لمدة خمس دقائق بتخلص من ال super net and بضيف او
+
+447
+00:30:57,580 --> 00:31:01,780
+بعمل resuspension لل sediment الموجود او للبلد
+
+448
+00:31:01,780 --> 00:31:09,060
+الموجود طبعا كده ال sediment بتكون جاهزة لعملية ال
+
+449
+00:31:09,060 --> 00:31:13,360
+IUI for example جاهزة لعملية ال IVF for example
+
+450
+00:31:13,360 --> 00:31:16,620
+بناء على طبيعة العينة او طبيعة ال process اللي انا
+
+451
+00:31:16,620 --> 00:31:19,990
+بدي استخدامهطبعا استخدمت عشر دقائق و بعدين عشر
+
+452
+00:31:19,990 --> 00:31:22,630
+دقائق و بعدين عشر دقائق يعني ممكن تاخد ل minimum
+
+453
+00:31:22,630 --> 00:31:27,110
+تلاتين دقيقة العملية ككل ما بين عملية ال first
+
+454
+00:31:27,110 --> 00:31:33,150
+centrifugation حتى ال last time أو ال last step
+
+455
+00:31:33,150 --> 00:31:37,630
+centrifugation طبعا مهم جدا جابل ما أكون جهزت
+
+456
+00:31:37,630 --> 00:31:43,090
+العينة و بعدتها ل ال empirical lab أو لعملية الحقن
+
+457
+00:31:43,090 --> 00:31:47,420
+بشكل أساسي لازم أعمل evaluationللعينة او للبلد او
+
+458
+00:31:47,420 --> 00:31:50,560
+لل cinnamon ان اشوف ماجدش فيه متايل sperm ماجدش
+
+459
+00:31:50,560 --> 00:31:54,420
+فيه count sperm بعد كده اعملها preparation
+
+460
+00:31:54,420 --> 00:31:58,480
+preparing for insemination insemination يعني الحقن
+
+461
+00:31:58,480 --> 00:32:02,900
+الحقن اي ماقصود فيه برجع بأكد ان هذه العملية بتاخد
+
+462
+00:32:02,900 --> 00:32:06,680
+لها كمية قليلة جدا من الوقت يعني تلاتين الاربعين
+
+463
+00:32:06,680 --> 00:32:10,960
+دقيقة يعني مش الوقت الكبير المرحلة التانية من
+
+464
+00:32:10,960 --> 00:32:13,720
+المرحلة التي تستخدم او الطريقة التانية طريقة ال
+
+465
+00:32:13,720 --> 00:32:16,400
+swarm upطبعاً طريقة this warm-up هي أكثر الطرق
+
+466
+00:32:16,400 --> 00:32:18,660
+التي يتم فيها استخدامها في ال research على سبيل
+
+467
+00:32:18,660 --> 00:32:22,500
+المثال و ال I.O.I. ال research و ال I.O.I. طبعاً
+
+468
+00:32:22,500 --> 00:32:25,240
+في هذه العملية أو عملية this warm-up ال principle
+
+469
+00:32:25,240 --> 00:32:29,140
+أساسي الخاص فيها أنه فقط ال spermatozoa التي
+
+470
+00:32:29,140 --> 00:32:32,940
+بتعتبر pest motility أو pest motile .. pest motile
+
+471
+00:32:32,940 --> 00:32:36,880
+spermatozoa هي التي تستطيع السباحة للأعلى يعني هنا
+
+472
+00:32:36,880 --> 00:32:41,180
+بفصل فقط ال motile sperm عن باقي ال spermatozoa عن
+
+473
+00:32:41,180 --> 00:32:45,170
+باقي ال depressedعن باقي الأمور التي لا نريد أن
+
+474
+00:32:45,170 --> 00:32:50,450
+تتواجد مع العينة ليه؟ لأن ببساطة جدا الحيوانات
+
+475
+00:32:50,450 --> 00:32:54,750
+المنوية الأكثر صحة الأكثر قدرة على الحركة التي
+
+476
+00:32:54,750 --> 00:32:57,950
+تعتبر حركتها طبيعية هي التي تستطيع أن تسبح للأعلى
+
+477
+00:32:57,950 --> 00:33:03,170
+طب ليه تسبح للأعلى؟ هنعرف ليه سميت أصلا سواقة طبعا
+
+478
+00:33:03,170 --> 00:33:06,130
+this procedure is very easy to perform and allowed
+
+479
+00:33:06,130 --> 00:33:07,970
+recovery for good number of progressive
+
+480
+00:33:07,970 --> 00:33:14,430
+spermatozoaفي مجموعة Normal Spermatozoa أو مجموعة
+
+481
+00:33:14,430 --> 00:33:22,490
+Normal Spermic طبعاً في البداية هذه الطريقة لديها
+
+482
+00:33:22,490 --> 00:33:25,530
+عديد من المفاتيح منها على سبيل المثال إنه بيعمل
+
+483
+00:33:25,530 --> 00:33:27,870
+reduction في percentage of normal chromatin
+
+484
+00:33:27,870 --> 00:33:31,610
+condensation in spermatozoa بيعمل why pellets
+
+485
+00:33:31,610 --> 00:33:35,330
+spermatozoa are in close contact with other cell
+
+486
+00:33:35,330 --> 00:33:38,450
+depressed anticocyte at the bottom of the tube
+
+487
+00:33:38,620 --> 00:33:42,460
+beginning exposure to the high level of ROS طبعا
+
+488
+00:33:42,460 --> 00:33:46,880
+طالما فقط ال spermatozoa التي تتميز بالجودموتالي
+
+489
+00:33:46,880 --> 00:33:50,580
+التي تسبح في الأعلى إذا أنا هفقد كمية كبيرة جدا من
+
+490
+00:33:50,580 --> 00:33:54,360
+ال spermatozoa في ال centrifugation و هدلها في
+
+491
+00:33:54,360 --> 00:33:58,260
+البلد وجودها في البلد يعني قريبة من ال leukocyte
+
+492
+00:33:58,260 --> 00:34:01,640
+قريبة من ال leukocyte يعني قريبة من ال ROS قريبة
+
+493
+00:34:01,640 --> 00:34:05,500
+من ال ROS يعني عندي ال ROS هيأثّر ال spermatozoa و
+
+494
+00:34:05,500 --> 00:34:08,970
+هيعمل لي destructure لهاعشان كده بلاقي عدد
+
+495
+00:34:08,970 --> 00:34:13,890
+الحيوانات المنوية التي تسبح للأعلى قليل جداً قد
+
+496
+00:34:13,890 --> 00:34:17,370
+تكون Normal Motile ولكن قد لا تكون Normal
+
+497
+00:34:17,370 --> 00:34:20,570
+Morphology أو Normal Sperm Condensation المادة
+
+498
+00:34:20,570 --> 00:34:24,390
+الوراثية مش هتكون .. ممكن ما تكونش Normal بنسبة
+
+499
+00:34:24,390 --> 00:34:29,410
+100% فبالتالي هذه تُعتبر من الطرق التي تُستخدم
+
+500
+00:34:29,410 --> 00:34:33,870
+طبعا أكثر استخدام هذه الطريقة في عملية الـ I.O.I
+
+501
+00:34:33,870 --> 00:34:38,880
+بسميتها Intra-UterineIn Semination كيف انا هتشتغل
+
+502
+00:34:38,880 --> 00:34:42,940
+هذه الفريقة و كيف بتتم ببساطة جدا بجيب عينة ال
+
+503
+00:34:42,940 --> 00:34:47,660
+seminal fluid بعمل mixing بينها و بين ال media
+
+504
+00:34:47,660 --> 00:34:52,880
+اسمها IOI media بنسبة 1 إلى 2 شو يعني 1 إلى 2؟
+
+505
+00:34:52,880 --> 00:34:58,280
+بمعنى اخر انا عندي 1ml سيمن بضيف عليها 2ml washing
+
+506
+00:34:58,280 --> 00:35:03,200
+culture media او IOI media او بسموها washing media
+
+507
+00:35:04,630 --> 00:35:08,670
+أو swarm up media اللي هي مسميات كتيرة عندى 1 مل
+
+508
+00:35:08,670 --> 00:35:12,530
+بضيف عليها 2 مل من ال media بعمل mixing طبعا هذا
+
+509
+00:35:12,530 --> 00:35:15,450
+في ال sterilized tube و بعمله centrifugation لمدت
+
+510
+00:35:15,450 --> 00:35:22,230
+10 دقائق على 2200 rpm بعد كده بتخلص من كل ال
+
+511
+00:35:22,230 --> 00:35:25,090
+supernatant ماليش علاقة بيه بعمله discard و moving
+
+512
+00:35:25,090 --> 00:35:31,030
+بعدين بضيف عليه نفس ال media بكمية معينة 1 مل 1.5
+
+513
+00:35:31,030 --> 00:35:35,430
+مل بناء على كمية البلة الموجودةولكن عملية إضافة ال
+
+514
+00:35:35,430 --> 00:35:38,950
+media هنا بت cool بشكل very slowly وعلى الجدار
+
+515
+00:35:38,950 --> 00:35:42,090
+الداخل للأنبوبة يعني باخد بالاسترالي و أضربها 1
+
+516
+00:35:42,090 --> 00:35:47,410
+mil أو 2 mil بإنها ماجدش عندي حجم ال pellet عندي
+
+517
+00:35:47,410 --> 00:35:50,370
+حجم ال pellet أو ال sediment 1 mil باخد 2 mil و
+
+518
+00:35:50,370 --> 00:35:54,650
+بميل الأنبوبة و بنزل السائل أو ال solution أو ال
+
+519
+00:35:54,650 --> 00:35:58,510
+media على الجدار الداخل للأنبوبة عشان مايصيرش drop
+
+520
+00:35:58,510 --> 00:36:05,160
+مرة واحدة مع ال sedimentبعد كده باخد الأنبوبة هذه
+
+521
+00:36:05,160 --> 00:36:11,460
+و بضيف ثراج بشكل مائل بزاوية 45 درجة و بحطه في ال
+
+522
+00:36:11,460 --> 00:36:17,540
+incubator لمدة 45 دقيقة على 37 درجة مائوية طبعا
+
+523
+00:36:17,540 --> 00:36:23,540
+هذه الإيمالة أو بزاوية 45 بالـdenis landship بساعد
+
+524
+00:36:23,540 --> 00:36:28,840
+ال spermatozoa أنها تسبح بسهولة نحو السطح فبالتالي
+
+525
+00:36:28,840 --> 00:36:32,900
+ما بيكون فيه قوة كبيرة جدابتواجد الـ spermatozoa
+
+526
+00:36:32,900 --> 00:36:36,140
+تقيق عملية السباحة للأعلى بالفعل الـ gravity فأنا
+
+527
+00:36:36,140 --> 00:36:39,140
+عملت عملية إيمان لإلها عشان أتقلل المسافة اللي
+
+528
+00:36:39,140 --> 00:36:42,340
+هتقطعها ال spermatozoa وما أجهد ال sperm لإن أنا
+
+529
+00:36:42,340 --> 00:36:46,360
+محتاج حركته في عملية ال fertilization بعد ما اتخلص
+
+530
+00:36:46,360 --> 00:36:53,200
+ال 40 أو ال 45 دقيقة باجي بطلع ال أنبوبة برفعها
+
+531
+00:36:53,200 --> 00:36:56,840
+باجي supernatant بعد ما كانت clear صار تربط معناه
+
+532
+00:36:56,840 --> 00:37:00,900
+في spermatozoa صعدت للأعلىباخد كل الـ supernatant
+
+533
+00:37:00,900 --> 00:37:03,780
+اللي فيه spermatozoon و بضيفه في الـ sterile test
+
+534
+00:37:03,780 --> 00:37:08,160
+tube و بعمل evaluation للعينة من حيث ال count و من
+
+535
+00:37:08,160 --> 00:37:11,700
+حيث ال motility جدّيش فيها sperm و جدّيش فيها
+
+536
+00:37:11,700 --> 00:37:15,470
+متغير ال spermطبعاً هذه صورة بتوضح الكلام فيها
+
+537
+00:37:15,470 --> 00:37:18,490
+عندى test tube ضفت العينة واحد منه وضفت عليها
+
+538
+00:37:18,490 --> 00:37:21,890
+اتنين من ال media عملتلها mixing ثم تخلصت
+
+539
+00:37:21,890 --> 00:37:26,450
+centrifugation وتخلصت من السبرانيتل ضفت media أخرى
+
+540
+00:37:26,450 --> 00:37:30,590
+تتناسب مع كمية ال sediment الموجودة ضفتها وقمت
+
+541
+00:37:30,590 --> 00:37:34,250
+بوضعها في راك بزاوية 45 درجة مئوية ودخلتها ال
+
+542
+00:37:34,250 --> 00:37:38,910
+incubator على 37 درجة .. عفوا ضفتها في الراك
+
+543
+00:37:38,910 --> 00:37:42,990
+بزاوية 45 درجةبعدين أدخلت الراك بالأنبوبة داخل من
+
+544
+00:37:42,990 --> 00:37:48,850
+كيبيتو على درجة حرارة 37 درجة موية لمدة من 20 ل 40
+
+545
+00:37:48,850 --> 00:37:51,910
+دقيقة بعد كده هرفع الأنبوبة هلاجي ال supernatant
+
+546
+00:37:51,910 --> 00:37:55,330
+تيربت بعد ما كان clear دليل أنه في spermatozoon
+
+547
+00:37:55,640 --> 00:37:58,420
+باخد كل ال super net worth اللي موجود بالأعلى دون
+
+548
+00:37:58,420 --> 00:38:02,040
+ما ألامس ال sediment و بضيفها في مبوبة جديدة بعدين
+
+549
+00:38:02,040 --> 00:38:05,380
+باخد منه عشرة micro بعمله assessment علشان أشوف كم
+
+550
+00:38:05,380 --> 00:38:09,080
+في عندي sperm count و كم في عندي motile و كم في
+
+551
+00:38:09,080 --> 00:38:13,500
+عندي عدد من حيث عدد ال sperm طبعا هذه الطريقة
+
+552
+00:38:13,500 --> 00:38:18,080
+مابتحتاج skill معينة طريقة سهلة جدا رخيصة جدا
+
+553
+00:38:18,080 --> 00:38:23,120
+مابتحتاج لدست تيوب و media و أكثر استخدامها لل IVF
+
+554
+00:38:23,120 --> 00:38:24,920
+التقليدي بالإضافة
+
+555
+00:38:30,570 --> 00:38:35,230
+الطريقة التالتة التي تعتبر هي أكثر الطرق استخداما
+
+556
+00:38:35,230 --> 00:38:38,630
+طريقة الـDensity Gradient Centrifugation يعني
+
+557
+00:38:38,630 --> 00:38:43,050
+الفصل باستخدام الكثافة المختلفة أو طبقة الكثافية
+
+558
+00:38:43,050 --> 00:38:49,740
+المختلفة طبعاهذه التقنية هي تقنية مهمة جدًا لتختار
+
+559
+00:38:49,740 --> 00:38:53,640
+عدد كبير أو عدد كبير من مطايل السبرماتوزوة في حالة
+
+560
+00:38:53,640 --> 00:38:55,100
+عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد
+
+561
+00:38:55,100 --> 00:38:55,920
+عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد
+
+562
+00:38:55,920 --> 00:38:57,260
+عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد
+
+563
+00:38:57,260 --> 00:38:57,980
+عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد عدد
+
+564
+00:38:57,980 --> 00:39:08,900
+عدد عدد عدد عدد عدد عدد عدد عدد عدد
+
+565
+00:39:08,900 --> 00:39:09,520
+ع
+
+566
+00:39:14,210 --> 00:39:17,850
+العينات التي تُصنف على أنها Oligospermia أو
+
+567
+00:39:17,850 --> 00:39:23,070
+Teratospermia أو Asinodyspermia طبعاً، in this
+
+568
+00:39:23,070 --> 00:39:25,890
+method, good quality sperm can be separated from
+
+569
+00:39:25,890 --> 00:39:29,270
+dead sperm أمر طبيعي، from leukocyte، from other
+
+570
+00:39:29,270 --> 00:39:32,490
+compounds of the seminal plasma by density
+
+571
+00:39:32,490 --> 00:39:35,770
+discontinuous gradient ماهي المقصود فيه؟ ال
+
+572
+00:39:35,770 --> 00:39:39,090
+density discontinuous gradient يعني كثافة متدرجة
+
+573
+00:39:39,090 --> 00:39:44,290
+غير متصلةمن حيث الكثافة ما بقول كل لنبوبة 90%
+
+574
+00:39:44,290 --> 00:39:48,090
+كثافتها هنحكي عنها إشي عن كثافة متدرجة أو كثافة
+
+575
+00:39:48,090 --> 00:39:52,650
+غير متواصلة فكرتها إنه أنا بفصل ال good sperm من
+
+576
+00:39:52,650 --> 00:39:56,430
+حيث ال quality عن ال other spermatozoa عن ال bad
+
+577
+00:39:56,430 --> 00:39:59,270
+quality sperm عن ال dead sperm عن ال ecocide عن ال
+
+578
+00:39:59,270 --> 00:40:02,210
+depress عن ال other material فكيف أنا بدي أشتغلها
+
+579
+00:40:02,210 --> 00:40:06,450
+ببساطة جدا ببساطة جدا بجيب test tube بضيف فيها
+
+580
+00:40:06,450 --> 00:40:11,020
+عندي two type of media نفس ال mediaولكن with
+
+581
+00:40:11,020 --> 00:40:13,960
+different concentrations كدا بسميها two types of
+
+582
+00:40:13,960 --> 00:40:18,780
+media من حيث ال density وليس من حيث النوع two
+
+583
+00:40:18,780 --> 00:40:23,320
+types of media according to density not according
+
+584
+00:40:23,320 --> 00:40:27,400
+to composition فنفرض إن ال media الأولى تركيزة 40
+
+585
+00:40:27,400 --> 00:40:30,860
+و ال media الأولى كثافتها 40 و ال media التانية
+
+586
+00:40:30,860 --> 00:40:38,080
+كثافتها 80 فباخد ببساطة جدا بجيب ال test tube بضيف
+
+587
+00:40:38,080 --> 00:40:43,520
+عليهاtop layer 40% يعني بمعنى أخر بجيب ال media
+
+588
+00:40:43,520 --> 00:40:47,680
+اللي كثافتها 80% و أضيف واحد منه بعدين كده بجيب ال
+
+589
+00:40:47,680 --> 00:40:51,920
+media اللي كثافتها 40% و أضيف واحد منه آخر بشرط أن
+
+590
+00:40:51,920 --> 00:40:55,500
+الإضافة تكون بشكل مائل عشان مايصير strong mix
+
+591
+00:40:55,500 --> 00:41:00,460
+between two type of media فهتكون ال layer السفلة
+
+592
+00:41:00,460 --> 00:41:04,800
+لها علاقة بال media اللي كثافتها 80% بينما ال
+
+593
+00:41:04,800 --> 00:41:08,720
+layer العلوية لها علاقة بال media اللي كثافتها 40%
+
+594
+00:41:09,440 --> 00:41:13,060
+بعدين بجيب 2ml .. طبعا خدوا بالكوا النسبة لازم
+
+595
+00:41:13,060 --> 00:41:17,000
+تكون 1 إلى 1 حطت 1ml من ال media الأولى هتكون 1ml
+
+596
+00:41:17,000 --> 00:41:20,700
+من ال media التانية و 1ml من ال seminal fluid أو
+
+597
+00:41:20,700 --> 00:41:28,020
+العينة حطت 2ml 80% و 2ml 40% بعدين ضفت العينة و
+
+598
+00:41:28,020 --> 00:41:33,270
+قلت هتكون 2ml من عينة ال semen ما بعمل mix؟وعملية
+
+599
+00:41:33,270 --> 00:41:36,690
+الإضافة بتكون بشكل very slowly على الجدار الداخل
+
+600
+00:41:36,690 --> 00:41:40,350
+للأنبوبة عشان مايصيرش mix بين الطبقات الداخلية من
+
+601
+00:41:40,350 --> 00:41:46,370
+الأسفل لأعلى media 8% و2% و140% ورقم 3 seminal
+
+602
+00:41:46,370 --> 00:41:51,410
+flow بعمله centrifugation على 300xg لمدة 20 minute
+
+603
+00:41:51,410 --> 00:41:56,430
+بطلّع الأنبوبة بكل بساطة و بدون استأجال عشان
+
+604
+00:41:56,430 --> 00:42:01,720
+ماعملش mix حلاجة في عندي انقسام separatingمن
+
+605
+00:42:01,720 --> 00:42:04,860
+الأعلى للأسفل سيكون في الأعلى الـ Seminal Fluid
+
+606
+00:42:04,860 --> 00:42:08,220
+يليه بالـ sperm, other debris, bacteria,
+
+607
+00:42:08,420 --> 00:42:11,960
+dipethylamin, immature, non mature, spermatozoa,
+
+608
+00:42:12,080 --> 00:42:16,160
+pellet, other target يعني سيكون عندي فقط طبقتين
+
+609
+00:42:16,160 --> 00:42:20,640
+الطبقة العلوية هي الـ Seminal Fluid بكل ما ذكرنا و
+
+610
+00:42:20,640 --> 00:42:23,260
+الطبقة السفلية هي ال pellet اللي فيها ال target
+
+611
+00:42:23,260 --> 00:42:27,140
+بأخد
+
+612
+00:42:27,140 --> 00:42:31,930
+كل الطبقة العلويةبدون أعمل أي touch لل ballot و
+
+613
+00:42:31,930 --> 00:42:36,730
+برميها بعملها discard we don't need it بعد كده
+
+614
+00:42:36,730 --> 00:42:41,530
+transfer the spare ballot to the new tube and then
+
+615
+00:42:41,530 --> 00:42:45,210
+add 5ml of your spare wash في ناس بتاخد ال ballot
+
+616
+00:42:45,210 --> 00:42:49,410
+لتسة تيوب جديدة و في ناس أصلا بتضيف على ال ballot
+
+617
+00:42:49,410 --> 00:42:54,650
+مباشرة و بتعملها mixing من pure media و pure wash
+
+618
+00:42:54,650 --> 00:42:56,870
+media خمسة ميل بضيفه على ال ballot بعمله
+
+619
+00:42:56,870 --> 00:43:00,950
+resuspensioncentrifugation لمدة 10 دقائق على 500
+
+620
+00:43:00,950 --> 00:43:06,190
+XG بعمل remove all the pure sperm washing except
+
+621
+00:43:06,190 --> 00:43:09,730
+the last one mil بمعنى أخر بعد ما أضفت الخمسة mil
+
+622
+00:43:09,730 --> 00:43:13,290
+وعملت centrifugation لمدة عشر دقائق باخد ال test
+
+623
+00:43:13,290 --> 00:43:16,950
+tube برفع أربع mil من الخمسة mil برميهم و بخل أخر
+
+624
+00:43:16,950 --> 00:43:20,450
+واحد mil اللي فيه spermatozoa اللي أنا بديها اللي
+
+625
+00:43:20,450 --> 00:43:24,210
+سميتها target spermatozoa ممكن أخد منها عشرة micro
+
+626
+00:43:24,210 --> 00:43:29,210
+و أعمل evaluation للعينة و أشوف كميةالـ sperm من
+
+627
+00:43:29,210 --> 00:43:32,950
+حيث ال concentration وقداش كمية ال sperm من حيث
+
+628
+00:43:32,950 --> 00:43:38,130
+motility as percentage طبعا هذه شكل ال conical
+
+629
+00:43:38,130 --> 00:43:43,970
+test tube أنا أضفت ال layer الأولى 2 mil وليكن من
+
+630
+00:43:43,970 --> 00:43:49,690
+الميدة التركيزة أو كثفتها 80 بعض الأحيان 90 وطبقة
+
+631
+00:43:49,690 --> 00:43:53,350
+تانية 2 mil من الميدة اللي كثفتها 40وبعض الأحيان
+
+632
+00:43:53,350 --> 00:43:56,530
+طبعا 45 فهو بنادأ بناء على شركة على شركة في شركة
+
+633
+00:43:56,530 --> 00:43:58,970
+بتعمل 80 اربعين وفي شركة بتعمل 90 اربعين و45
+
+634
+00:43:58,970 --> 00:44:03,710
+اربعين وكذا بعد انضفت اتنين ميل من العينة ادخلتهم
+
+635
+00:44:03,710 --> 00:44:06,010
+ال centrifugation بعد انتهاء ال centrifugation
+
+636
+00:44:06,010 --> 00:44:09,570
+اللي جات فيه عند كل السيمون الفلويد في الأعلى بما
+
+637
+00:44:09,570 --> 00:44:14,340
+يحتوي من material unwantedوالـ Target ماتيريا
+
+638
+00:44:14,340 --> 00:44:17,440
+الموجودة في الـ Sediment بتخلص من الـ Supernatant
+
+639
+00:44:17,440 --> 00:44:21,720
+وبضيف عليها خمسة مل من Pure Washing Solution
+
+640
+00:44:21,720 --> 00:44:25,340
+بعملها Mixing و Centrifugation بعد كده بتخلص من
+
+641
+00:44:25,340 --> 00:44:29,520
+أربع مل وبترك الواحد مل كما هو و هو اللي فيه
+
+642
+00:44:29,520 --> 00:44:34,400
+Target إذا الواحد مل الأخير هو اللي فيه Target
+
+643
+00:44:34,400 --> 00:44:38,500
+Spermatozoa with high quality باخد منها عشرة micro
+
+644
+00:44:38,500 --> 00:44:41,420
+بعملها evaluation assessment عشان يشوف كدهش ال
+
+645
+00:44:41,420 --> 00:44:44,410
+total countكداش ال concentration، كداش ال
+
+646
+00:44:44,410 --> 00:44:47,330
+motility، كداش ال progressiveotype، و كده بتكون
+
+647
+00:44:47,330 --> 00:44:52,930
+العين جاهزة لل exit سنستكفي بهذا القدر ان شاء الله
+
+648
+00:44:52,930 --> 00:44:58,090
+على أمل أن نلتقي في محاضرات مستقبلية تم تم في حفظ
+
+649
+00:44:58,090 --> 00:44:59,270
+الوريعات
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/C8pUDf7Uze8_postprocess.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/C8pUDf7Uze8_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..9126603c8c24520059c04200a35727387e9afd37
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/C8pUDf7Uze8_postprocess.srt
@@ -0,0 +1,2112 @@
+1
+00:00:01,250 --> 00:00:05,090
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,090 --> 00:00:09,750
+المرسلين سيدنا محمد الصادق الأمين أما بعد بداية
+
+3
+00:00:09,750 --> 00:00:14,970
+نرحب بكم في مصاف مواضيع خاصة في العلوم الطبية
+
+4
+00:00:14,970 --> 00:00:19,980
+المخبرية لطلبة الماجستير المستوى الثانياتحدثنا في
+
+5
+00:00:19,980 --> 00:00:25,200
+اللقاء التعريفي عن محتويات هذا المصدق وقد أسلفنا
+
+6
+00:00:25,200 --> 00:00:29,840
+أن هذا المصدق سوف يتحدث عن تقنية مهمة جدا وهي
+
+7
+00:00:29,840 --> 00:00:33,580
+تقنية التلقيح الصناعي أو أطفال الأنابيب أو ما
+
+8
+00:00:33,580 --> 00:00:38,380
+يُعرف حاليا بالحقن المجهري حكينا إن هناك تلت طرق
+
+9
+00:00:38,380 --> 00:00:44,160
+مختلفة هي عبارة عن عملية التلقيح الصناعي أو أطفال
+
+10
+00:00:44,160 --> 00:00:47,970
+الأنابيب وهي عبارة عن الطريقة التقليديةثم ارتقت
+
+11
+00:00:47,970 --> 00:00:52,390
+فيما بعد إلى الحقن المجهري الذي يُعرف باختصار IGC
+
+12
+00:00:52,390 --> 00:00:57,590
+أي Intracytoplasmic sperm injection تكلمنا في
+
+13
+00:00:57,590 --> 00:01:01,670
+البداية عن محتوى هذا المصاق ما على الطلاب من
+
+14
+00:01:01,670 --> 00:01:06,070
+واجبات وما على المدرس من التزامات وواجبات أيضا
+
+15
+00:01:06,070 --> 00:01:10,950
+توقفنا عن أسباب ال IGC واليوم سنستكمل هذا الموضوع
+
+16
+00:01:10,950 --> 00:01:15,520
+حول مصطلح مهم جدا وهو ال infertilityال infertility
+
+17
+00:01:15,520 --> 00:01:20,600
+ككلمة تعني عدم القدرة على الإنجاب فال infertility
+
+18
+00:01:20,600 --> 00:01:26,500
+ككلمة بشكلها العام و شكلها المعروف هي عدم قدرة
+
+19
+00:01:26,500 --> 00:01:31,040
+الزوجين على الحصول على طفل خلال فترة زمنية معينة
+
+20
+00:01:31,040 --> 00:01:35,480
+ولكن للأسف في مجتمعنا الحالي أو مجتمعنا المتواجد
+
+21
+00:01:35,480 --> 00:01:40,220
+الآن هناك اختلاف في المعنى ما بين العقوم و عدم
+
+22
+00:01:40,220 --> 00:01:44,020
+القدرة على الإنجابواسلفنا فيما سبق إن العكم هو
+
+23
+00:01:44,020 --> 00:01:48,420
+الـsterility وعدم القدرة على الإنجاب بأي شكل من
+
+24
+00:01:48,420 --> 00:01:53,480
+الأشكال أما ال infertility وهي عبارة عن مشكلة
+
+25
+00:01:53,480 --> 00:01:58,640
+يواجهها بعض الناس أو بعض العائلات هي عبارة عن تأخر
+
+26
+00:01:58,640 --> 00:02:02,380
+الإنجاب أو عدم القدرة على الإنجاب بالطريقة
+
+27
+00:02:02,380 --> 00:02:06,120
+التخلدية وللأسف، بناء على العادات والتقاليد
+
+28
+00:02:06,120 --> 00:02:09,860
+الموجودة في مجتمعنادائما أي two couples تبدو حياة
+
+29
+00:02:09,860 --> 00:02:14,620
+جديدة متى سوف يتم الإنجاب وينتأخر الإنجاب لفترة
+
+30
+00:02:14,620 --> 00:02:18,940
+زمنية بسيطة تقدر بشهور و لو خمسة شهور أو ستة شهور
+
+31
+00:02:18,940 --> 00:02:24,100
+أو سنة يصنفهم المجتمع يصنفه على إنه infertile أو
+
+32
+00:02:24,100 --> 00:02:28,000
+غير قادر على الإنجاب طبعا هذا مصطلح خاطئ جدا
+
+33
+00:02:28,000 --> 00:02:33,320
+وتصنيف خاطئ جدا التعريف العلمي لل infertility هي
+
+34
+00:02:33,320 --> 00:02:38,170
+عبارة عن عدم القدرة على الإنجاب بشرطفي فترة زمانية
+
+35
+00:02:38,170 --> 00:02:45,290
+تقدر بسنة واحدة من بعد الزواج بشرط أن يكون هناك
+
+36
+00:02:45,290 --> 00:02:52,610
+نية للإنجاب بشكل مستمر علشان كده يُعرف بإنه يُعرف
+
+37
+00:02:52,610 --> 00:02:56,150
+هذا المصطلح بإنه usually defined as inability to
+
+38
+00:02:56,150 --> 00:03:01,010
+get pregnant after trying for one year of regular
+
+39
+00:03:01,010 --> 00:03:05,010
+sexual intercourse without any contraceptive يعني
+
+40
+00:03:05,010 --> 00:03:08,910
+في عندك two couplesعندهم الرغبة في الإنجاب و
+
+41
+00:03:08,910 --> 00:03:13,970
+بيحاولوا .. و بيحاولوا بيسعوا في الإنجاب للحصول
+
+42
+00:03:13,970 --> 00:03:16,670
+على طفل سواء كان طبعا male أو female بغض النظر عن
+
+43
+00:03:16,670 --> 00:03:20,810
+جنس المولود حاليا ولكن لا يملكوا القدرة خلال هذه
+
+44
+00:03:20,810 --> 00:03:23,910
+السنة إذا فقدوا القدرة على الإنجاب بنسميهم
+
+45
+00:03:23,910 --> 00:03:29,090
+infertile طب هل ال infertility تعتبر مشكلة؟ وهل
+
+46
+00:03:29,090 --> 00:03:33,920
+تصنف بناء على التصنيفات الألمية مشكلة؟صحيح تعتبر
+
+47
+00:03:33,920 --> 00:03:37,300
+من أكتر المشاكل الانتشارة سواء كان في المجتمع
+
+48
+00:03:37,300 --> 00:03:41,980
+الغربي أو المجتمع العربي أو الشرقي رغم كثافة
+
+49
+00:03:41,980 --> 00:03:46,760
+السكانية الموجودة زيها زي السمنة زيها زي الـ
+
+50
+00:03:46,760 --> 00:03:52,100
+Diabetes زيها زي blood pressure تصنف كحالة مرضية
+
+51
+00:03:52,100 --> 00:03:57,860
+حوالين العالم تقدر ال infertility بحوالي 8 إلى 12%
+
+52
+00:03:57,860 --> 00:04:00,790
+between two couples يعني عندي لو أنا عنديmeat
+
+53
+00:04:00,790 --> 00:04:06,690
+couples منهم 12% يصنفوا على إنهم infertile على
+
+54
+00:04:06,690 --> 00:04:09,670
+سبيل المثال في ال united states كانت النسبة أعلى
+
+55
+00:04:09,670 --> 00:04:13,530
+تصل إلى 15% يعني لو أنا عنده meat couples بطلّق
+
+56
+00:04:13,530 --> 00:04:18,250
+منهم 15 couples infertile ولو توجهنا إلى المجتمعات
+
+57
+00:04:18,250 --> 00:04:23,570
+الغربية هنلاقي كنسبة بتزيد يعني على سبيل المثال
+
+58
+00:04:23,570 --> 00:04:27,190
+ألمانيا بلاقي نسبة ال infertility عالية جدا و ال
+
+59
+00:04:27,190 --> 00:04:32,300
+infertility دي مش سببها أمورطبية، ولكن فقدان الـ
+
+60
+00:04:32,300 --> 00:04:36,540
+two couples الرغبة في اقتناء طفل أو امتلاك طفل أو
+
+61
+00:04:36,540 --> 00:04:40,780
+الحصول على طفل طبيعة مجتمع، طبيعة عاداته تقاليد في
+
+62
+00:04:40,780 --> 00:04:45,440
+ال United States حوالي 15 أو 10% من السيدات اللي
+
+63
+00:04:45,440 --> 00:04:52,020
+عمهم يتروح ما بين 15 إلى 44 سنة يصنفوا بعدم القدرة
+
+64
+00:04:52,020 --> 00:04:56,900
+على الإنجاب بشكل طبيعي أو عدم القدرة على الاحتفاظ
+
+65
+00:04:56,900 --> 00:05:01,200
+بالجنين بشكله الطبيعيليش صنف الخمستعش لأربع
+
+66
+00:05:01,200 --> 00:05:04,540
+واربعين سنة؟ لأن الخمستعش و الأربع و أربعين سنة
+
+67
+00:05:04,540 --> 00:05:08,680
+العمر الواقع ما بينهم يعتبر هو سن الإنجاب عند
+
+68
+00:05:08,680 --> 00:05:13,900
+السيدة فحوالي من كل ميت سيدة عمرها خمستعش إلى أربع
+
+69
+00:05:13,900 --> 00:05:18,020
+واربعين سنة بطلّها منهم عشر سيدات تفقد القدرة على
+
+70
+00:05:18,020 --> 00:05:22,360
+الاحتفاظ بالجنين غير قادرة على الإنجاب بشكل طبيعي
+
+71
+00:05:22,360 --> 00:05:28,820
+وتصنف بأنها infertileبأنها infertile، هذا التعريف
+
+72
+00:05:28,820 --> 00:05:32,680
+الأساسي هل هناك تعريف أخر لل infertility؟ أكيد
+
+73
+00:05:32,680 --> 00:05:36,020
+هناك تعريف أخر ل infertility فعلى سبيل المثال لو
+
+74
+00:05:36,020 --> 00:05:39,120
+أنا عرفت ال infertility according to reproductive
+
+75
+00:05:39,120 --> 00:05:42,940
+age يعني بمناعة اخر أنا بدي أصنف ال infertility
+
+76
+00:05:42,940 --> 00:05:46,660
+بناء على العمر الإنجابي، طبعا ال male له عمر
+
+77
+00:05:46,660 --> 00:05:51,100
+إنجابي يختلف عن ال femaleالمال عمر الإنجابي من 16
+
+78
+00:05:51,100 --> 00:05:57,480
+حوالي ل 60 أو ل 50 طبعا زيادة العمر هيأثر على ال
+
+79
+00:05:57,480 --> 00:06:01,320
+ability of production عند المال بينما ال female ال
+
+80
+00:06:01,320 --> 00:06:06,160
+reproductive age محدود يقدر من على سبيل المثال من
+
+81
+00:06:06,160 --> 00:06:11,720
+مجتمع لمجتمع يختلف من 15 سنة ل 35 سنة ل 40 سنة
+
+82
+00:06:11,720 --> 00:06:16,190
+ماكسما هذا عبارة عن العمر الإنجابي عند السيدةطب
+
+83
+00:06:16,190 --> 00:06:18,830
+العمر الإنجابي عند ال male أطول؟ أكيد أطول وحنا
+
+84
+00:06:18,830 --> 00:06:22,990
+نعرف السبب كمان شوية إذا لو أنا قسمت ال
+
+85
+00:06:22,990 --> 00:06:26,170
+infertility أو عرفت ال infertility بتعريف آخر بناء
+
+86
+00:06:26,170 --> 00:06:30,410
+على ال reproductive age هو عدم قدرة ال two couples
+
+87
+00:06:30,410 --> 00:06:34,930
+على الإنجاب أو على الحصول على طفل خلال الفترة
+
+88
+00:06:34,930 --> 00:06:39,970
+الإنجابية التي تتروح من 15 ل 49 سنة إذا اندمجت ال
+
+89
+00:06:39,970 --> 00:06:43,230
+male مع ال female to become or remain pregnant
+
+90
+00:06:43,610 --> 00:06:46,970
+within five years of exposure to pregnancy يعني
+
+91
+00:06:46,970 --> 00:06:52,750
+أنا عندي سيدات عمرهم يتروح من 15 إلى 49 سنة فقدوا
+
+92
+00:06:52,750 --> 00:06:57,410
+القدرة على الإنجاب لمدة خمس سنوات متتالية رغم
+
+93
+00:06:57,410 --> 00:07:00,850
+المحاولة
+
+94
+00:07:00,850 --> 00:07:06,290
+المستمرة من أجل إنجاب طفل بسميها infertile تعريف
+
+95
+00:07:06,290 --> 00:07:10,370
+آخر بسمي inability to become pregnant with live
+
+96
+00:07:10,370 --> 00:07:14,780
+pairs within five years of exposurebased on
+
+97
+00:07:14,780 --> 00:07:19,100
+constant unique status بمعنى آخر إن هذه ال women
+
+98
+00:07:19,100 --> 00:07:25,780
+تفقد القدرة على الإنجاب خلال خمس سنوات من المحاولة
+
+99
+00:07:25,780 --> 00:07:29,720
+على الإنجاب ولكن هنا صنف ال infertility كأنها
+
+100
+00:07:29,720 --> 00:07:34,000
+infertility ليس فقط القدرة على الحمل فقط ولكن
+
+101
+00:07:34,000 --> 00:07:38,620
+القدرة على الحصول life baby life birth يعني سيدة
+
+102
+00:07:38,620 --> 00:07:44,900
+تحمل وتحصل على طفل حيعلى قيد الحياة، يعني تصل
+
+103
+00:07:44,900 --> 00:07:49,240
+لمرحلة الولادة، فهذا تعريف آخر لل infertility بشرط
+
+104
+00:07:49,240 --> 00:07:53,960
+.. بشرط أن هذه السيدة تكون مازالت محافظة على
+
+105
+00:07:53,960 --> 00:07:59,560
+الرغبة في الإنجاب غير مرضعة ولا تتناول موانع حمل،
+
+106
+00:07:59,560 --> 00:08:02,880
+بنسميها oral contraception طب ليه السمة أو ليش
+
+107
+00:08:02,880 --> 00:08:07,690
+حافظة على تلت معايير الأساسية؟إن السيدة ما زالت
+
+108
+00:08:07,690 --> 00:08:11,170
+تملك القدرة على الإنجاب لإن هذه الأمور لها علاقة
+
+109
+00:08:11,170 --> 00:08:14,710
+بالأمور النفسية كمان شوية هنتعرف إن الأمور النفسية
+
+110
+00:08:14,710 --> 00:08:16,950
+و ال depression اللي بتعرض إليها ال male و ال
+
+111
+00:08:16,950 --> 00:08:20,870
+female يعمل على إنقاس القدرة على الإنجاب No
+
+112
+00:08:20,870 --> 00:08:25,130
+lactation أو lacting لإن عملية الإرضاع للطفل تؤدي
+
+113
+00:08:25,130 --> 00:08:28,690
+إلى تأخير عملية ال ovulation فبالتالي تؤدي إلى
+
+114
+00:08:28,690 --> 00:08:32,950
+تأخير عملية الإنجاب لإن ما بنعرف إن هرمون الحليب
+
+115
+00:08:33,760 --> 00:08:38,380
+الـ LH يؤثر على الدورة الخاصة بالسيدة، مما يؤدي
+
+116
+00:08:38,380 --> 00:08:42,040
+إلى تأخير عملية الإبادة، مما يؤدي إلى تأخير الحمض
+
+117
+00:08:42,040 --> 00:08:45,020
+السبب التالت هو الـ oral contraceptive الممكن
+
+118
+00:08:45,020 --> 00:08:49,160
+تتناول السيدة من أجل منع عملية الحمض فبالتالي،
+
+119
+00:08:49,160 --> 00:08:54,020
+السيدة حافظة على الرغبة على الإنجاب لم تتناول
+
+120
+00:08:54,020 --> 00:08:58,960
+موانع حمض وغير مرضعة، ولكنها غير قادرة على الإنجاب
+
+121
+00:08:58,960 --> 00:09:05,000
+أو الحصول على طفل حي، مولود حييعني بتحصل على جنين
+
+122
+00:09:05,000 --> 00:09:11,080
+حي بعد 9 شهور لمدة خمس سنوات متواصلة يمكن أن تصنف
+
+123
+00:09:11,080 --> 00:09:16,620
+بأنها infertile ما هي أسباب ال infertility عند ال
+
+124
+00:09:16,620 --> 00:09:19,940
+male وما هي أسباب ال infertility عند ال female؟
+
+125
+00:09:19,940 --> 00:09:24,140
+وهل هناك أسباب مختلفة أو أسباب متشابهة؟ أكيد تبع
+
+126
+00:09:24,140 --> 00:09:29,450
+الجنس و ال reproductive age هناك أسباب مختلفةسنبدأ
+
+127
+00:09:29,450 --> 00:09:33,030
+بأسباب ال infertility عند الفيميل وأولهم هيعرف اسم
+
+128
+00:09:33,030 --> 00:09:36,970
+tubular blockage كلمنا في المحاضرة السابقة إن ال
+
+129
+00:09:36,970 --> 00:09:41,070
+reproductive system عند الفيميل بيبدأ بالcervix،
+
+130
+00:09:41,070 --> 00:09:44,290
+بعدين الرحم أو عنق الرحم خلّيني أسميه، بعدين
+
+131
+00:09:44,290 --> 00:09:48,610
+الرحم، بعدين قنوات فلوك، بعدين المبيض هذا هو عبارة
+
+132
+00:09:48,610 --> 00:09:51,690
+عن ال reproductive system عند السيدة أي مشكلة في
+
+133
+00:09:51,690 --> 00:09:56,370
+أي منطقة من تلك المناطق يودي إلى حدوث infertility
+
+134
+00:09:56,660 --> 00:10:02,420
+قد تكون دائمة و قد تكون مؤقتة تحل بالإلاج قد يكون
+
+135
+00:10:02,420 --> 00:10:06,240
+إلاج عن طريق medication و قد يكون إلاج يستوجب
+
+136
+00:10:06,240 --> 00:10:09,640
+الجراحة سنتحدث عن هذا الموضوع أول سبب من أسباب ال
+
+137
+00:10:09,640 --> 00:10:13,300
+infertility هو عبارة عن انغلاق في الأنابيب أي
+
+138
+00:10:13,300 --> 00:10:18,820
+أنابيب أشهرها الفانوبيا نتيوب أول سبب من الأسباب
+
+139
+00:10:18,820 --> 00:10:23,180
+التي تؤدي إلى تأخر الإنجاب عند السيدة هي انغلاق
+
+140
+00:10:23,180 --> 00:10:27,990
+الأنابيب انغلاق الأنابيبشو بيعمل؟ ببساطة جدا أول
+
+141
+00:10:27,990 --> 00:10:32,550
+شغلة بشكل طلقائي يمنع وصول ال sperm إلى ال oocyte
+
+142
+00:10:32,550 --> 00:10:37,310
+لإن ال oocyte وهي البويضة إذا كانت ناضجة تلقح في
+
+143
+00:10:37,310 --> 00:10:42,010
+الفلوبيا نتيوب ولكي يتم التلقيح في الفلوبيا نتيوب
+
+144
+00:10:42,010 --> 00:10:46,230
+يجب على ال sperm أن يقطع منطقة عنق الرحم والرحم
+
+145
+00:10:46,230 --> 00:10:49,750
+ليصل إلى الفلوبيا نتيوب ويلقح البويضة في هذا
+
+146
+00:10:49,750 --> 00:10:53,930
+المكان فإذا صار عندى blockage في الفلوبيا نتيوب
+
+147
+00:10:53,930 --> 00:10:57,890
+أدبنها ال sperm أن يصللـ Targeted Place اللي موجود
+
+148
+00:10:57,890 --> 00:11:01,870
+فيها البويضة فبالتالي مش هيصير عملية التلقيح إذن
+
+149
+00:11:01,870 --> 00:11:07,690
+أول شغلة أن الـ Tepular Blockage تمنا لـ Pregnancy
+
+150
+00:11:07,690 --> 00:11:12,490
+من خلال منع الستر من الوصول إلى البويضة و تلقيحها
+
+151
+00:11:12,490 --> 00:11:19,150
+أو من خلال منع وصول البويضة الملقحة إلى الرحم لأن
+
+152
+00:11:19,150 --> 00:11:23,370
+البويضة بعد ما تتلقح في ال Fallopian Tube المفروض
+
+153
+00:11:23,600 --> 00:11:26,780
+تسافر من الـ Fallopian tube حتى تصل إلى الرحم
+
+154
+00:11:26,780 --> 00:11:31,600
+وتنغرز في بطانة الرحم لتكوين الجنين اللي فيما بعد
+
+155
+00:11:31,600 --> 00:11:35,200
+يكوّن لـ Placenta أو لتكوين الـ Placenta التي تؤدي
+
+156
+00:11:35,200 --> 00:11:41,540
+إلى مصدر غذاء للجنين فعندي طريقتين أو two way للـ
+
+157
+00:11:41,540 --> 00:11:45,940
+tubular blockage التي تؤدي لمنع الحمض أول حاجة منع
+
+158
+00:11:45,940 --> 00:11:49,400
+وصول الحيوان المنو ال sperm إلى البويضة مما يمنع
+
+159
+00:11:49,400 --> 00:11:54,210
+التلقيح منعانتقال البويضة الملقحة من الـ Fallopian
+
+160
+00:11:54,210 --> 00:11:58,310
+tube إلى الرحم مما يؤدي إلى عدم تكوين الجنين
+
+161
+00:11:58,310 --> 00:12:02,410
+فبالتالي المحصلة سفر في الشيبرجنانسي السبب التاني
+
+162
+00:12:02,410 --> 00:12:05,950
+عند الفيميل حاجة بنتسميها Endometriosis ببساطة جدا
+
+163
+00:12:05,950 --> 00:12:09,270
+Endometriosis مصطلح من ال Endometrium و ال
+
+164
+00:12:09,270 --> 00:12:13,350
+Endometrium هي عبارة عن النسيج المبطن للرحم أو
+
+165
+00:12:13,350 --> 00:12:17,690
+بطانة الرحم بسموهافي بعض الأحيان وبعض الحالات
+
+166
+00:12:17,690 --> 00:12:21,690
+المرضية بيصير في عندي خلل في الأنسجة المبطنة للرحم
+
+167
+00:12:21,690 --> 00:12:25,410
+اللي بنسميها بطنط الرحم أو ال endometerium فبصير
+
+168
+00:12:25,410 --> 00:12:30,030
+إليها انتقال أو نمو خارج الرحم انتقال ال
+
+169
+00:12:30,030 --> 00:12:35,310
+endometerium ونموها خارج الرحم يؤدي إلى تكوين
+
+170
+00:12:35,310 --> 00:12:39,150
+pregnancy failure يؤدي إلى تكوين pregnancy failure
+
+171
+00:12:39,150 --> 00:12:43,800
+لأنه بيبنع عملية أصلا التبويضأو قد يمنع وصول
+
+172
+00:12:43,800 --> 00:12:48,320
+البوايضة الملقحة إلى المكان المناسب لتكوين الجنين
+
+173
+00:12:48,320 --> 00:12:51,560
+داخل الرحم السبب التالت بنسميه حاجة بنسميها
+
+174
+00:12:51,560 --> 00:12:55,600
+cervical factor cervical factor يعني عوامل لها
+
+175
+00:12:55,600 --> 00:13:00,520
+علاقة بأنق الرحم وأن أنق الرحم يعتبر أول محطات
+
+176
+00:13:00,520 --> 00:13:04,460
+انتقال ال sperm بعد ال .. بعد ال .. ال .. ال .. ال
+
+177
+00:13:04,460 --> 00:13:05,080
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+178
+00:13:05,080 --> 00:13:05,680
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+179
+00:13:05,680 --> 00:13:06,800
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+180
+00:13:06,800 --> 00:13:07,680
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+181
+00:13:07,680 --> 00:13:08,180
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+182
+00:13:08,180 --> 00:13:08,260
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+183
+00:13:08,260 --> 00:13:12,010
+.. ال .. ال .. ال .. ال .. ال .. ال .. الor
+
+184
+00:13:12,010 --> 00:13:15,130
+antagonist to sperm يعني في عندى في ال cervical
+
+185
+00:13:15,130 --> 00:13:20,190
+factor two factors الأول كمية الميوكاس الموجودة في
+
+186
+00:13:20,190 --> 00:13:26,130
+منطقة ال cervical كمية قليلة جدا هى أدلها way تمنع
+
+187
+00:13:26,130 --> 00:13:30,370
+حدوث ال pregnancy او الشيء التانى ان وجود في منطقة
+
+188
+00:13:30,370 --> 00:13:35,230
+ال cervical sperm يعمل ك antagonist يعني مضاد أو
+
+189
+00:13:35,230 --> 00:13:39,330
+مواد تستخدم او مواد موجودة عفوا مواد موجودة في
+
+190
+00:13:39,330 --> 00:13:42,650
+منطقة ال cervicalتعمل ك antagonist ضد ال sperm
+
+191
+00:13:42,650 --> 00:13:45,430
+يعني مجرد ما يتواجد ال sperm في منطقة ال cervical
+
+192
+00:13:45,430 --> 00:13:49,210
+هذه المواد بتعمل destructure ل ال sperm فبالتالي
+
+193
+00:13:49,210 --> 00:13:53,350
+ال sperm يفقد قدرته على الانتقال ثم يفقد قدرته على
+
+194
+00:13:53,350 --> 00:13:57,550
+الإخصاد ال ant sperm antibody من أهم هذه المواد
+
+195
+00:13:57,550 --> 00:14:01,750
+اللتي تعمل ك antagonist against sperm في بعض
+
+196
+00:14:01,750 --> 00:14:05,730
+الأحيان بيكون اندي two couples normal 100% ال male
+
+197
+00:14:05,730 --> 00:14:09,650
+و ال female لاندو crime level normalال Anatomy تبع
+
+198
+00:14:09,650 --> 00:14:12,490
+ال pelvic عند ال male و ال female normal ال
+
+199
+00:14:12,490 --> 00:14:15,630
+Anatomy ال productive system عند ال male و ال
+
+200
+00:14:15,630 --> 00:14:18,890
+female normal بنسبة 100% ولكن غير قادرين على
+
+201
+00:14:18,890 --> 00:14:24,090
+الإنجاب السبب أن هذه الزوجة أو هذه ال female عندها
+
+202
+00:14:24,090 --> 00:14:29,670
+ant sperm موجودة في منطقة ال cervic تشتغل ضد ال
+
+203
+00:14:29,670 --> 00:14:33,730
+sperm الخاص بهذا الرجل أو خاص بهذا الزوجة فبالتالي
+
+204
+00:14:33,940 --> 00:14:39,820
+لا يحدث تلقيح للبويضة حتى لو كانت البويضة نادجة
+
+205
+00:14:39,820 --> 00:14:43,360
+لأن مافيه spear بيصل للبويضة النادجة وبيعملها
+
+206
+00:14:43,360 --> 00:14:48,140
+عملية تلقيح فبالتالي ال ant spear من أهم الأسباب
+
+207
+00:14:48,140 --> 00:14:54,200
+التي تؤدي إلى منع تلقيح البويضة والتي تؤدي إلى قتل
+
+208
+00:14:54,200 --> 00:14:59,200
+الحيوان بمجرد تواجده في منطقة ال cervical فمجرد
+
+209
+00:14:59,200 --> 00:15:03,060
+أنه اشتغلت هذا ال ant spear ضد ال spear فبيعملها
+
+210
+00:15:03,320 --> 00:15:07,000
+انتاجونيست بتفقد ال capacity تبع ال sperm على ال
+
+211
+00:15:07,000 --> 00:15:11,260
+fertilization سؤال هل يمكن للذكر تكوين ant sperm
+
+212
+00:15:11,260 --> 00:15:14,980
+ضد نفسه أو ضد الحيوانات المنوية الخاصة فيه؟ صحيح
+
+213
+00:15:14,980 --> 00:15:20,560
+يمكن في أدت حالات رغم علميا أن ال testes الخاصة
+
+214
+00:15:20,560 --> 00:15:24,620
+بالميل موجودة في منطقة معزولة عن ال blood stream
+
+215
+00:15:24,620 --> 00:15:29,020
+بشكل كامل فبالتالي ما في الها ما بتعرضلها جهاز
+
+216
+00:15:29,020 --> 00:15:33,420
+المناعةولكن في لحظة من اللحظات بخطأ طبي بسيط على
+
+217
+00:15:33,420 --> 00:15:36,840
+سبيل المثال لو صار عندك trauma أو injury في منطقة
+
+218
+00:15:36,840 --> 00:15:39,800
+ال testis بيصير في عندك direct contact ما بين
+
+219
+00:15:39,800 --> 00:15:44,800
+immune system و ال testis فبادي إلى تكوين antibody
+
+220
+00:15:44,800 --> 00:15:48,600
+ضد ال sperm الخاص بهذا الإنسان فيصبح الإنسان غير
+
+221
+00:15:48,600 --> 00:15:52,260
+قادر على الإنجاب بفئة جهازه المناعي بفئة جهازه
+
+222
+00:15:52,260 --> 00:15:58,140
+المناعي فبتكون السيدة ما إلها سبب في تأخر الإنجاب
+
+223
+00:15:58,140 --> 00:16:01,740
+في هذه اللحظةفي أمور تانية بنسميها cervical factor
+
+224
+00:16:01,740 --> 00:16:06,140
+could be physical problem or mucus related problem
+
+225
+00:16:06,140 --> 00:16:10,340
+بعض الأحيان ال cervical factor قسموها إلى عوامل
+
+226
+00:16:10,340 --> 00:16:14,960
+فيزيائية علاقة مثلا بال thickness الخاصة بالميوكاس
+
+227
+00:16:14,960 --> 00:16:20,220
+أو عوامل ليس لها علاقة بال physical أبدا فعلى سبيل
+
+228
+00:16:20,220 --> 00:16:25,280
+المثال لو كان عندي cervical mucus very thick
+
+229
+00:16:25,280 --> 00:16:28,320
+الميوكاس الموجود في منطقة ال cervical عند السيدة
+
+230
+00:16:28,870 --> 00:16:33,770
+very very very thick هذا بيعمل كشبكة شبكة مغلقة
+
+231
+00:16:33,770 --> 00:16:39,250
+محكمة الإغلاق تمنع انتقال أي sperm داخل ال
+
+232
+00:16:39,250 --> 00:16:42,950
+cervical فبالتالي ما بيقطع ال cervical وما بيقطع
+
+233
+00:16:42,950 --> 00:16:47,270
+الرحم وما بيصل لل Fallopian tube فبالتالي ال
+
+234
+00:16:47,270 --> 00:16:51,130
+fertilization محصلة سفر فماعندي pregnancy صرفي
+
+235
+00:16:51,130 --> 00:16:55,670
+عندي infertility و لو كانت موقفة شغل تاني أقول ليه
+
+236
+00:16:56,310 --> 00:17:00,990
+الـ physical problem الخاصة بالـ cervic لها علاقة
+
+237
+00:17:00,990 --> 00:17:04,750
+بشكل كبير جدا جدا بالـ miscarriage والـ
+
+238
+00:17:04,750 --> 00:17:09,030
+miscarriage بشكل أساسي هو عبارة عن الإجهاض الـ
+
+239
+00:17:09,030 --> 00:17:12,870
+miscarriage زي ال abortion الإجهاض الـ mucus
+
+240
+00:17:12,870 --> 00:17:16,510
+related problem ممكن يؤدي لميوكس إلى عدة مشاكل
+
+241
+00:17:16,510 --> 00:17:20,750
+بفعل كمية الميوكس الموجودة في ال cervical غير
+
+242
+00:17:20,750 --> 00:17:25,380
+كافية فبالتاليالـ sperm غير قادر على البقاء طب إيش
+
+243
+00:17:25,380 --> 00:17:28,360
+دخل ال mucus في بقاء ال sperm؟ طب إحنا حكينا إن ال
+
+244
+00:17:28,360 --> 00:17:33,080
+mucus بيقتل ال sperm خد بالك يقتل ال sperm في حالة
+
+245
+00:17:33,080 --> 00:17:37,240
+زيادة ال thickness تبع ال mucus فبالتالي وجود ال
+
+246
+00:17:37,240 --> 00:17:41,780
+mucus في منطقة ال cervical بعمل عملية حماية لل
+
+247
+00:17:41,780 --> 00:17:45,380
+sperm من ال pH الخاص بال cervical ال pH اللي
+
+248
+00:17:45,380 --> 00:17:49,100
+موجودة عند السيدة لإن ال pH تبع ال male يختلف عن
+
+249
+00:17:49,100 --> 00:17:53,030
+ال pH تبع ال female فلو كان في عنديفيش عنده
+
+250
+00:17:53,030 --> 00:17:56,150
+ميوكاس، هيصير عنده shock للـ sperm ويصيرله
+
+251
+00:17:56,150 --> 00:18:01,650
+destructure فكمية الـ mucus المعقولة والكافية تعمل
+
+252
+00:18:01,650 --> 00:18:07,250
+حماية للـ sperm بعد الintercourses من أجل المحافظة
+
+253
+00:18:07,250 --> 00:18:10,390
+على الـ sperm بال full activity الخاصة فيه للوصول
+
+254
+00:18:10,390 --> 00:18:14,830
+إلى ال fallopian tube ففي حالة وجود كمية غير كافية
+
+255
+00:18:14,830 --> 00:18:19,770
+من الميوكاس، معناه ال survivor rate للـ sperm هقل
+
+256
+00:18:19,770 --> 00:18:27,060
+بشكل كبيرis too thick for sperm to survive لو كان
+
+257
+00:18:27,060 --> 00:18:32,500
+لدي الميوكاس ثقبته عالية جدا أو الدنسته عالية جدا
+
+258
+00:18:32,500 --> 00:18:37,160
+معناه أن كمية ال sperm اللي هتصل إلى الفلوبيا
+
+259
+00:18:37,160 --> 00:18:40,620
+هتكون قليلة جدا لأن الميوكاس في هذا اللحظة عمل زي
+
+260
+00:18:40,620 --> 00:18:45,400
+شبكة أسطاد كل sperm وعملهم ال structureالحاجة
+
+261
+00:18:45,400 --> 00:18:48,980
+التالتة بيسموها The Mucus Contains Spam Antibody
+
+262
+00:18:48,980 --> 00:18:53,160
+اتكلمنا عليها في مصابق ان الميوكاس نفسه في منطقة
+
+263
+00:18:53,160 --> 00:18:56,780
+الـ cervical الخاص بالفيميل يحتوي على Antibody
+
+264
+00:18:56,780 --> 00:19:00,580
+طبعا Antibody في هذه اللحظة السيدة اللتي تصنعه
+
+265
+00:19:00,580 --> 00:19:06,600
+وليس الراجل السيدة وليس الراجل السبب الرابع حاجة
+
+266
+00:19:06,600 --> 00:19:10,740
+بيسمونها الـ Belvic Adhesion ببساطة في بعض الأحيان
+
+267
+00:19:10,740 --> 00:19:14,900
+السيدات بتتعرض ل trauma في منطقة ال belvicأو تتعرض
+
+268
+00:19:14,900 --> 00:19:18,300
+لـ inflammation في منطقة الـ pelvic أو بتتعرض ل
+
+269
+00:19:18,300 --> 00:19:21,920
+surgical operation في منطقة الـ pelvic عملية الـ
+
+270
+00:19:21,920 --> 00:19:25,620
+healing للتيشو في منطقة الـ pelvic تؤدي في بعض
+
+271
+00:19:25,620 --> 00:19:29,480
+الأحيان إلى تكوين pelvic adhesion الـ pelvic
+
+272
+00:19:29,480 --> 00:19:32,460
+adhesion ببساطة زي ما احنا شايفنا في الصورة هي
+
+273
+00:19:32,460 --> 00:19:39,340
+عبارة عن فلمة اتطورت، نمت بشكل كبير جداعملت رابط
+
+274
+00:19:39,340 --> 00:19:42,960
+لبعض الأعضاء الموجودة في منطقة ال abdominal ومنطقة
+
+275
+00:19:42,960 --> 00:19:47,840
+ال pelvic عند السيدة فأدت إلى وجود anatomical ..
+
+276
+00:19:47,840 --> 00:19:50,560
+anatomical structure لـ reproductive system غير
+
+277
+00:19:50,560 --> 00:19:56,000
+طبيعي فأدى إلى عدم القدرة على الإنجاب عدم القدرة
+
+278
+00:19:56,000 --> 00:20:00,000
+على الإنجاب السبب الأساسي أن هذه السيدة اتعرضت ل
+
+279
+00:20:00,000 --> 00:20:04,200
+trauma inflammation surgical operation في منطقة ال
+
+280
+00:20:04,200 --> 00:20:08,350
+pelvic بعد فترة صار healing لل tissueالـ healing
+
+281
+00:20:08,350 --> 00:20:12,710
+كون filament الـ filament أملت ربط لبعض الأعضاء
+
+282
+00:20:12,710 --> 00:20:16,090
+الموجودة في منطقة ال بالبج مع بعض البعض فأدى إلى
+
+283
+00:20:16,090 --> 00:20:20,470
+تكوين anatomical structure abnormal shape او
+
+284
+00:20:20,470 --> 00:20:25,530
+abnormal anatomical structure أدى إلى تأخر الإنجاب
+
+285
+00:20:25,530 --> 00:20:30,730
+أو حدوث infertility سبب
+
+286
+00:20:30,730 --> 00:20:34,990
+الخامس الذي يعتبر من أسباب ال female infertility
+
+287
+00:20:34,990 --> 00:20:39,450
+هو عبارة عنOvulation Disorder يعني السيدة تمام
+
+288
+00:20:39,450 --> 00:20:42,830
+مافيش عندها Antisperm Antibody مافيش عندها Pelvic
+
+289
+00:20:42,830 --> 00:20:46,890
+Adhesion ال Anatomical Reproductive System Normal
+
+290
+00:20:46,890 --> 00:20:51,950
+ولكن في عندها مشكلة في عملية ال Ovulation نفسها
+
+291
+00:20:51,950 --> 00:20:56,190
+يعني في عملية التبويض نعرف بشكل أساسي و بشكل مبدئي
+
+292
+00:20:56,190 --> 00:21:00,710
+أن المتعرف عليه ان ال menstrual cycle لأي سيدة 28
+
+293
+00:21:00,710 --> 00:21:04,570
+يوم من إلى من لحظة ال bleeding إلى ال bleeding
+
+294
+00:21:05,390 --> 00:21:07,930
+التاني الموجود في الـ cycle التاني يعني 28 يوم
+
+295
+00:21:07,930 --> 00:21:11,510
+ولكن هذا ميثابت في بعضهم تصل لـ 30 وفي بعضهم تصل
+
+296
+00:21:11,510 --> 00:21:15,750
+لـ 36 يوم زي ما احنا بنعرف ان ال pleading time
+
+297
+00:21:15,750 --> 00:21:19,610
+تمان تيام في بعضهم أربع في بعضهم عشر في بعض
+
+298
+00:21:19,610 --> 00:21:24,030
+السيدات بيكون عندهم ovulation disorder يعني بمعنى
+
+299
+00:21:24,030 --> 00:21:28,110
+أخر ان في عوامل بتأثر على عملية ال egg releasing
+
+300
+00:21:28,110 --> 00:21:31,750
+ايش عن ال ovulation؟ ovulation هي عبارة عن التبويض
+
+301
+00:21:31,750 --> 00:21:35,500
+أو الإبادةإيش معنى التفويض أو الإبادة؟ هي عبارة عن
+
+302
+00:21:35,500 --> 00:21:39,800
+خروج البويضة الناضجة من الـ ovary إلى قناة
+
+303
+00:21:39,800 --> 00:21:42,500
+Fallopian هذه بسميها الـ ovulation طبعا دايما
+
+304
+00:21:42,500 --> 00:21:45,520
+بتصير في اليوم التلتاش أو اليوم الأربعة عشر من
+
+305
+00:21:45,520 --> 00:21:49,600
+الدورة الشهرية اللي بيسميها menstrual cycle بعض
+
+306
+00:21:49,600 --> 00:21:54,100
+السيدات عندهم مشكلة في وقت التفويض أو عندهم مشكلة
+
+307
+00:21:54,100 --> 00:21:57,060
+في قليل التفويض أو عندهم مشكلة في كيفية التفويض
+
+308
+00:21:57,060 --> 00:22:00,260
+عندهم عملية إخراج البويضةأو عملية الـ ovulation
+
+309
+00:22:00,260 --> 00:22:04,260
+بشكل الطبيعي لأ مابتحدث، أسبابها شوف في عندى
+
+310
+00:22:04,260 --> 00:22:07,320
+هرمون، فمش داخل الهرمون في الموضوع هذا؟ ببساطة
+
+311
+00:22:07,320 --> 00:22:10,440
+جدا، عارفين أن ال reproductive system و ال
+
+312
+00:22:10,440 --> 00:22:14,820
+ovulation ما بيصير إلا تحت تأثير الهرمونات، وأهمها
+
+313
+00:22:14,820 --> 00:22:19,740
+ال FSH و ال LH اللي فيما بعد بيحفظ الإنتاج
+
+314
+00:22:19,740 --> 00:22:23,500
+للبروجسترون و الاستروجين، وهذا هناخده بالتفصيل
+
+315
+00:22:23,500 --> 00:22:28,280
+الممل في chapter رقم 2 ان شاء اللهإذا الأول سبب من
+
+316
+00:22:28,280 --> 00:22:31,700
+أسباب الـ ovulation disorder أنه في عندي hormonal
+
+317
+00:22:31,700 --> 00:22:35,860
+disorder ومن أشهرها ال polycystic ovarian syndrome
+
+318
+00:22:35,860 --> 00:22:39,180
+شو مقصود بال polycystic ovarian syndrome؟ حاجة
+
+319
+00:22:39,180 --> 00:22:45,400
+بيسموها PCOS Polycystic
+
+320
+00:22:45,400 --> 00:22:50,020
+Ovarian Syndrome يعني في عندي تكييسات حول المبيض
+
+321
+00:22:50,020 --> 00:22:56,180
+تمنع عملية الإبادة تحجب عملية الإبادة تمنع خروج
+
+322
+00:22:57,400 --> 00:23:00,800
+البوايضة في ناس بتقولك لأ انه انا عندى الفوليكل
+
+323
+00:23:00,800 --> 00:23:05,420
+اللى موجود فيها البوايضة بتنتفخ و بتكبر لدرجة انه
+
+324
+00:23:05,420 --> 00:23:10,640
+انا لو شوفتها ال ultrasound باعتبرها فوليكل طبيعية
+
+325
+00:23:10,640 --> 00:23:16,140
+تحتوي على بوايضة طبيعية ناضجة ولكن لو دققت النظر
+
+326
+00:23:16,140 --> 00:23:20,020
+فيها بلاج الفوليكل فاضية مافيها بوايضة ناضجة عشان
+
+327
+00:23:20,020 --> 00:23:24,620
+كده بيسموها polycystic ovary syndrome polycystic
+
+328
+00:23:24,620 --> 00:23:29,720
+ovary syndrome يعني الفوليكلوصلت للديامتر الخاص
+
+329
+00:23:29,720 --> 00:23:33,740
+بالفوليكيل الناضجة ولكن في داخلها Zero بويضات
+
+330
+00:23:33,740 --> 00:23:38,440
+ناضجة سبب التاني حاجة بنتسميها Hyperproto .. حاجة
+
+331
+00:23:38,440 --> 00:23:44,200
+.. اللي لها علاقة بال .. ال .. Lactemia يعني ..
+
+332
+00:23:44,200 --> 00:23:47,960
+هرمون الحليب .. اللي لها علاقة بهرمون الحليب زيادة
+
+333
+00:23:47,960 --> 00:23:53,080
+في مستوى هرمون الحليب Prolactin hormone حاجة
+
+334
+00:23:53,080 --> 00:23:56,730
+بنتسميها Hyperprolactinemiaيعني مستوى هرمون الحليب
+
+335
+00:23:56,730 --> 00:24:01,330
+بيكون عالي جدا فبتتأخر عملية التبويض اللي احنا
+
+336
+00:24:01,330 --> 00:24:05,070
+بنسميها بالمصطلح العام تأخر الدورة عشان كده معظم
+
+337
+00:24:05,070 --> 00:24:07,990
+السيدات اللي بينجبوا و بكونوا في مرحلة الرضاعة ال
+
+338
+00:24:07,990 --> 00:24:11,150
+lactation بلاجئ الدورة ما بتيجي بشكل منتظم أو
+
+339
+00:24:11,150 --> 00:24:15,330
+بتتأخر شهرين تلاتة و ممكن تتأخر سنة كاملة عند بعض
+
+340
+00:24:15,330 --> 00:24:21,210
+السيدات سبب التالت لل ovulation disorder هي too
+
+341
+00:24:21,210 --> 00:24:24,890
+much thyroid hormone اللي بنسميهاhyperthyroidism
+
+342
+00:24:24,890 --> 00:24:28,630
+أو hypothyroidism سيدة عندها thyroid hormone
+
+343
+00:24:28,630 --> 00:24:32,270
+activity عالي جدا بتسميها hyperthyroidism أو very
+
+344
+00:24:32,270 --> 00:24:36,430
+low بتسميها hypothyroidism وهذا بيأثر بشكل كبير
+
+345
+00:24:36,430 --> 00:24:41,270
+جدا على ال ovulation و ال menstrual cycle عشان كده
+
+346
+00:24:41,270 --> 00:24:45,490
+أي سيدة .. خدوا بالكوا .. أي سيدة بتروح تعمل إجزي
+
+347
+00:24:45,490 --> 00:24:49,990
+تلقيح صناعي أو حق المجهري بيقصولها هرمونات ال FSH
+
+348
+00:24:49,990 --> 00:24:57,180
+و ال LH و ال E2والـ TSH هو Thyroid Stimulating
+
+349
+00:24:57,180 --> 00:25:00,280
+Hormone Thyroid Stimulating Hormone وكمان هرمون
+
+350
+00:25:00,280 --> 00:25:05,340
+جديد بيسموه AMH Anti-Mullerian Hormone وحنتكلم عنه
+
+351
+00:25:05,340 --> 00:25:09,360
+باستفادة شو هو الـ Anti-Mullerian Hormone علشان
+
+352
+00:25:09,360 --> 00:25:14,140
+كده مهم جدا الـ prolactin يكون طبيعي مهم جدا ال
+
+353
+00:25:14,140 --> 00:25:18,960
+FSH يكون طبيعي مهم جدا ال LH يكون طبيعي مهم جدا ال
+
+354
+00:25:18,960 --> 00:25:24,960
+E2مهم جداً الـ TSH يكون طبيعي قبل الزوجة أو السيدة
+
+355
+00:25:24,960 --> 00:25:31,140
+ما تروح تعمل إجزي وإلا هتدخل في برنامج علاجي يرجع
+
+356
+00:25:31,140 --> 00:25:35,520
+هذه الهرمونات لوضعها كالطبيعي ال other causes اللي
+
+357
+00:25:35,520 --> 00:25:39,960
+بتأدي إلى ال ovulation disorder بعض الأحيان أن هذه
+
+358
+00:25:39,960 --> 00:25:45,080
+السيدة بتعمل exercise بشكل hard exercise hard
+
+359
+00:25:45,080 --> 00:25:50,490
+exercise بيأدي إلى حدوث تلفعندها في بعض المناطق
+
+360
+00:25:50,490 --> 00:25:54,050
+الخاصة بال reproductive system eating disorder أو
+
+361
+00:25:54,050 --> 00:26:00,190
+tumor بعض الأحيان بصير عندها tumor في منطقة ال
+
+362
+00:26:00,190 --> 00:26:04,650
+بالبك tumor في ال ovary tumor في الفلوجياليتيوب
+
+363
+00:26:04,650 --> 00:26:10,530
+تمنع عملية ال ovulation بالشكل الطبيعي سبب سادس من
+
+364
+00:26:10,530 --> 00:26:15,050
+أسباب ال female infertility وهو primary ovarian
+
+365
+00:26:15,050 --> 00:26:15,770
+insufficiency
+
+366
+00:26:18,060 --> 00:26:20,240
+What's the meaning of the primary or variant
+
+367
+00:26:20,240 --> 00:26:24,200
+sufficient هو عبارة عن ال early monopioes ال
+
+368
+00:26:24,200 --> 00:26:27,740
+monopioes أنا ما بدي أسميها فترة اليأس أو زمن
+
+369
+00:26:27,740 --> 00:26:32,500
+اليأس أو وقت اليأس أنا بسميها لبساطة جدا انقطاع
+
+370
+00:26:32,500 --> 00:26:37,700
+الدورة أو انقطاع الطمف بعضهم من أجل تغيير الوصولات
+
+371
+00:26:37,700 --> 00:26:43,100
+بسميها سن الأمد لأ هو عبارة عن وقت انقطاع الدورة
+
+372
+00:26:43,100 --> 00:26:47,980
+أو وقت انقطاع الطمف بسموها monopioesفي هذا السبب
+
+373
+00:26:47,980 --> 00:26:52,220
+اللي بنسميه Primary Ovarian Insufficiency إله اسم
+
+374
+00:26:52,220 --> 00:26:56,980
+آخر وهو الـ Early Monobiosis السيدة بشكلها الطبيعي
+
+375
+00:26:56,980 --> 00:27:00,040
+و بعمرها الطبيعي و ال physiological الطبيعية
+
+376
+00:27:00,040 --> 00:27:03,100
+الخاصة فيها تصل لـ Monobiosis أربعين و أحد و
+
+377
+00:27:03,100 --> 00:27:05,860
+أربعين و أتنين و أربعين سنة يعني لما تصل لعمر من
+
+378
+00:27:05,860 --> 00:27:08,020
+أربعين لتانين و أربعين سنة المفروض كانت وصلت لـ
+
+379
+00:27:08,020 --> 00:27:10,940
+Monobiosis و هنعرف أيش الأسباب التي تؤدي إلى الـ
+
+380
+00:27:10,940 --> 00:27:16,830
+Monobiosis ولكن لكل قاعدةشواذ في بعض السيدات ما
+
+381
+00:27:16,830 --> 00:27:20,290
+بتصل لـ Monobios على ال 40 بتصل على 35 هذا
+
+382
+00:27:20,290 --> 00:27:25,250
+بنتسميها Early Monobios Early Monobios و طبعا
+
+383
+00:27:25,250 --> 00:27:29,390
+بعضهم أو بعض المقالات بتقولك أنه .. و بعض المراجع
+
+384
+00:27:29,390 --> 00:27:34,530
+بتقولك أن أسبابها unknown حتى الآن ولكن في factors
+
+385
+00:27:34,530 --> 00:27:39,850
+تساعد و ترتبط بال Early Monobios منها عندك problem
+
+386
+00:27:39,850 --> 00:27:42,790
+في ال immune systemهيصير ال immune system يشتغل
+
+387
+00:27:42,790 --> 00:27:48,070
+على ال بويضات المخزنة بيدمرها وبتصل ل 35-36 ما
+
+388
+00:27:48,070 --> 00:27:52,010
+بيكون عندها مخزون وبتتوقف الدورة عندها او بعض اللي
+
+389
+00:27:52,010 --> 00:27:54,410
+أحيان بيقولك في عندي genetical condition زي
+
+390
+00:27:54,410 --> 00:27:58,790
+الternal syndrome زي ال fragile egg syndrome أو
+
+391
+00:27:58,790 --> 00:28:01,530
+بعض السيدات اللي بتتعرضوا لل radiotherapy و ال
+
+392
+00:28:01,530 --> 00:28:06,150
+chemotherapy إذا هذه عبارة عن تلت عوامل أساسية
+
+393
+00:28:06,150 --> 00:28:11,860
+تساعد وتدفعالسيدة للوصول إلى الـ Airline Monobios
+
+394
+00:28:11,860 --> 00:28:15,840
+قبل الوقت الطبيعي يعني قبل الأربعين في خلصه تلقين
+
+395
+00:28:15,840 --> 00:28:21,420
+ستة أولوية طيب خلصنا من أسباب الـ Monobios عند
+
+396
+00:28:21,420 --> 00:28:25,500
+الفيميل عفوا خلصنا عند أعوام الـ Monobios أو
+
+397
+00:28:25,500 --> 00:28:29,820
+Airline Monobios عند الفيميل وبالتالي أنهينا
+
+398
+00:28:29,820 --> 00:28:34,460
+الأسباب التي تؤدي إلى الـ Female Infertility نيجي
+
+399
+00:28:34,460 --> 00:28:37,000
+لـ Male Infertility ولكن قبل ما نيجي لـ Male
+
+400
+00:28:37,000 --> 00:28:44,480
+Infertilityمش صح إنه أنا أرجع و أعود بأسباب ال
+
+401
+00:28:44,480 --> 00:28:48,240
+infertility إلى شخص دون الآخر أو إلى جنس دون الآخر
+
+402
+00:28:48,240 --> 00:28:52,420
+ولا بقول إن ال infertility لها علاقة بال female أو
+
+403
+00:28:52,420 --> 00:28:56,200
+لها علاقة بال male لأ في أسباب خاصة بال male في
+
+404
+00:28:56,200 --> 00:28:59,600
+أسباب خاصة بال female فبالتالي قبل ما أطلق أي حاجة
+
+405
+00:28:59,600 --> 00:29:04,640
+و أقول إن ال infertility خاصة بال female فبالتالي
+
+406
+00:29:04,640 --> 00:29:08,690
+لازم أنا أستشير طبيبأستشير أخصائي البريولوجيست
+
+407
+00:29:08,690 --> 00:29:13,050
+أعمل الفحوصات المطلوبة عشان أحدد السبب علشان بعد
+
+408
+00:29:13,050 --> 00:29:17,230
+تحديد السبب بدأ الإلاج فبالتالي ما بلقي التهم
+
+409
+00:29:17,230 --> 00:29:22,750
+جوزافة أسباب ال male infertility بداية لما أقول
+
+410
+00:29:22,750 --> 00:29:27,110
+أنا عندي infertility عند ال male معناه إن هذا ال
+
+411
+00:29:27,110 --> 00:29:33,920
+male قد ينتج seminal fluid ولكن مافي spermأو قد
+
+412
+00:29:33,920 --> 00:29:38,000
+ينتج seminal fluid وفي sperm ولكن الـ sperm non
+
+413
+00:29:38,000 --> 00:29:41,840
+-functional يعني بمعنى أخر ممكن يكون أنا عندي
+
+414
+00:29:41,840 --> 00:29:46,040
+مشكلة في ال seminal fluid composition أو ممكن يكون
+
+415
+00:29:46,040 --> 00:29:50,700
+عندي مشكلة في المصنع و هو ال testis بس لأ ممكن
+
+416
+00:29:50,700 --> 00:29:54,780
+يكون عندي مشكلة أيضا في القنابيب الناقلة من المصنع
+
+417
+00:29:54,780 --> 00:29:59,080
+إلى ال .. إلى ال .. إلى .. خلّيني أسميه ال ..
+
+418
+00:30:02,470 --> 00:30:05,710
+النبوبة القاضي فخلّيني أسميها بهذا الشكل فبالتالي
+
+419
+00:30:05,710 --> 00:30:10,510
+في عندي مرحلة التصنيع مرحلة النقل والمنتج المنتج
+
+420
+00:30:10,510 --> 00:30:13,330
+هو عبارة عن الـ seminal fluid ممكن يكون عندي مشكلة
+
+421
+00:30:13,330 --> 00:30:16,770
+في مرحلة التصنيع في المصنع في المصنع هو ال testis
+
+422
+00:30:16,770 --> 00:30:20,890
+ممكن يكون عندي مشكلة في ال vas deferens وهو
+
+423
+00:30:20,890 --> 00:30:24,570
+الأنابيب الناقلة وممكن يكون عندي مشكلة في العينة
+
+424
+00:30:24,570 --> 00:30:29,570
+يعني كل ما سبق طبيعي ولكن المشكلة في العينة بمعنى
+
+425
+00:30:29,570 --> 00:30:35,090
+آخرإن العينة ما فيها sperm أو العينة فيها sperm
+
+426
+00:30:35,090 --> 00:30:38,670
+ولكن عدده قليل أو العينة فيها sperm وعدده 100%
+
+427
+00:30:38,670 --> 00:30:42,170
+ولكن non-functional غير قادر على الإتجاب أو غير
+
+428
+00:30:42,170 --> 00:30:45,910
+قادر على التلقيح هي المقصود فيه فبالتالي ال
+
+429
+00:30:45,910 --> 00:30:51,810
+problem with sperm ال problem with sperm خلّيني
+
+430
+00:30:51,810 --> 00:30:56,750
+أقول إن الأسباب المرتبطة بالعقوم عند الرجال لها
+
+431
+00:30:56,750 --> 00:31:02,790
+عدة سببلو أنا بتاخد على مستوى ال testis فيه أسباب
+
+432
+00:31:02,790 --> 00:31:05,770
+على مستوى ال fast difference و العنابيب الناقلة
+
+433
+00:31:05,770 --> 00:31:09,970
+فيه أسباب و عوامل على مستوى العينة بحد ذاتها فيه
+
+434
+00:31:09,970 --> 00:31:15,130
+أسباب و عوامل أيضا ولكن بشكل عام أن عندي some man
+
+435
+00:31:15,130 --> 00:31:19,950
+produce no sperm فبسميه asospermia زي ما حكينا في
+
+436
+00:31:19,950 --> 00:31:25,350
+slide ما قبل الأخيرة المحاضرة السابقة أو somemale
+
+437
+00:31:25,350 --> 00:31:29,950
+produce seminal fluid with a few number of sperm
+
+438
+00:31:29,950 --> 00:31:34,050
+بنسميها oligospermia العينة ككل بنسميها seminal
+
+439
+00:31:34,050 --> 00:31:38,930
+fluid ال sperm ال بالداخل إذا كان طبيعي بنسميه
+
+440
+00:31:38,930 --> 00:31:43,250
+normal seminal fluid طبعا إذا كان طبيعي من حياته
+
+441
+00:31:43,250 --> 00:31:47,970
+العدد من حياته الحركة من حياته الحجم ومن حياته ال
+
+442
+00:31:47,970 --> 00:31:51,070
+progressive motility اللي هتكلم عنها بشكلها الأوضح
+
+443
+00:31:51,070 --> 00:31:55,780
+ولكن إذا كان عدد الحيوانات المنوية في العينةأقل من
+
+444
+00:31:55,780 --> 00:32:02,340
+20 مليون بسميها Oligospermia بسميها Oligospermia
+
+445
+00:32:02,340 --> 00:32:06,380
+طيب other problem include في عندي sexual
+
+446
+00:32:06,380 --> 00:32:11,020
+dysfunction عند مشاكل في الأعضاء التناثورية الخاصة
+
+447
+00:32:11,020 --> 00:32:14,440
+بالميل فبالتالي ما بتقوم بالوظيفة المطلوبة منه
+
+448
+00:32:14,440 --> 00:32:18,420
+ومنها في عندي hormonal and endocrine abnormality
+
+449
+00:32:18,420 --> 00:32:23,570
+مثلا عند مشكلة في ال FSH عند مشكلة في ال LHعندي
+
+450
+00:32:23,570 --> 00:32:27,330
+مشكلة في الـ Testosterone لأنه هو الهرمون الذكوري
+
+451
+00:32:27,330 --> 00:32:30,470
+الموجود عند الذكور و ال Progesterone هو الهرمون
+
+452
+00:32:30,470 --> 00:32:34,950
+الأنثوي الموجود عند الإناس فبالتالي لو كان عندي
+
+453
+00:32:34,950 --> 00:32:38,390
+مشكلة في ال FSH و ال LH ال Testosterone معناه
+
+454
+00:32:38,390 --> 00:32:42,370
+مشكلة عندي في عملية الإنتاج Infection صار عند هذا
+
+455
+00:32:42,370 --> 00:32:45,710
+ال male Infection في ال testis أو Infection في ال
+
+456
+00:32:45,710 --> 00:32:50,690
+accessory gland أو حاجة نسموها الغدد المساعدة
+
+457
+00:32:50,750 --> 00:32:54,210
+فبالتالي مش هينتج حيوانات منوية بالشكل المطلوب و
+
+458
+00:32:54,210 --> 00:32:57,530
+بالكم المطلوب و بالكفاءة المطلوب Congenital
+
+459
+00:32:57,530 --> 00:33:02,290
+problems like pear defect such as the absence of
+
+460
+00:33:02,290 --> 00:33:05,130
+tubule that carried the sperm و هي ال vase
+
+461
+00:33:05,130 --> 00:33:09,430
+difference بعض الذكور بيولدوا عندهم مشكلة في ال
+
+462
+00:33:09,430 --> 00:33:12,390
+vase difference و هو القنطوب الناقل أو الوعاء
+
+463
+00:33:12,390 --> 00:33:17,470
+الناقل مفقود فبالتالي المصنع شغال و يخلق ولكن مافي
+
+464
+00:33:17,470 --> 00:33:22,400
+شيء ينقل من الداخل للخارجطبعا هدولة يعتبروا
+
+465
+00:33:22,400 --> 00:33:27,180
+infertile .. infertile غير قادر عن جبب بشكل طبيعي
+
+466
+00:33:27,180 --> 00:33:32,500
+ولكن لو أنا روحت أعملتله حاجة بتسميها تيسا أو بيسا
+
+467
+00:33:32,500 --> 00:33:36,440
+يكون .. ممكن يكون قادر عن جبب طبعا شو التيسا و شو
+
+468
+00:33:36,440 --> 00:33:41,740
+البيسا هتكلم عنها في محاضرات لاحقة إن شاء الله
+
+469
+00:33:41,740 --> 00:33:47,400
+ببساطة تعريفة أنا باخد عينة أو خزعة من ال testis
+
+470
+00:33:47,400 --> 00:33:52,570
+نفسهGenetic Chromosomal Abnormality من الأسباب
+
+471
+00:33:52,570 --> 00:33:56,910
+التي قد تؤدي إلى المال Infertility بعض الأسباب
+
+472
+00:33:56,910 --> 00:34:00,910
+والمشاكل التي لها علاقة بالكرومزوم أو بعض المشاكل
+
+473
+00:34:00,910 --> 00:34:05,250
+الجينية Anti-Sperm Antibody حكينا أن المال يمكن
+
+474
+00:34:05,250 --> 00:34:08,710
+يكون Anti-Sperm Antibody صحيح ضد نفسه إذا اتعرض
+
+475
+00:34:08,710 --> 00:34:12,410
+لترومة في منطقة الـ Reproductive System
+
+476
+00:34:12,410 --> 00:34:16,510
+الـVaricoseal الدوالي وهي عبارة عن انتفاخات في
+
+477
+00:34:16,510 --> 00:34:20,200
+الأواعي الدموية الموصلة لهالدم والغذاء الى ال
+
+478
+00:34:20,200 --> 00:34:24,280
+testis فبتصير عندي Varicosel تؤدي الى تأخر الإنجاب
+
+479
+00:34:24,280 --> 00:34:27,460
+يعني تؤدي الى infertility لها علاج صحيح لها علاج
+
+480
+00:34:27,460 --> 00:34:30,760
+ال lifestyle ممكن تأثر على ال number و ال quality
+
+481
+00:34:30,760 --> 00:34:35,300
+تبع ال sperm ال lifestyle يعني تتحدث عنها بلا حرج
+
+482
+00:34:35,300 --> 00:34:42,020
+زى التدخين زى الدخان و الشيشة و العمل في مصنع
+
+483
+00:34:42,020 --> 00:34:45,360
+البطاريات العمل في مصانع ال sponge التعرض لدرجات
+
+484
+00:34:45,360 --> 00:34:49,300
+حرارة عالية لفترة وقت زمنية طويلةالتعرض للفسفور
+
+485
+00:34:49,300 --> 00:34:55,560
+الأبيض وخلافه الالكحول and drug ممكن تسبب
+
+486
+00:34:55,560 --> 00:34:59,000
+abnormality وممكن في ال semen parameter أو ممكن
+
+487
+00:34:59,000 --> 00:35:02,700
+تؤدي إلى reduction في ال seminal quality أو في ال
+
+488
+00:35:02,700 --> 00:35:06,440
+sperm quality بشكل مؤقت لأن ال cigarette smoking
+
+489
+00:35:06,440 --> 00:35:09,640
+تأثيره عند ال male يختلف عن تأثيره عند ال female
+
+490
+00:35:09,640 --> 00:35:13,560
+ولكن اللي بدأنا أعرفه أن الالكحول و ال cigarette
+
+491
+00:35:13,560 --> 00:35:16,920
+smoking في الغالب تأثيره بكون temporary عند ال
+
+492
+00:35:16,920 --> 00:35:23,790
+maleلأن الـ seminal fluid أو الـ sperm ما بيخزن
+
+493
+00:35:23,790 --> 00:35:27,630
+لفترات زمنية طويلة جدا لأ هو في حالة تخليق بشكل
+
+494
+00:35:27,630 --> 00:35:31,070
+مستمر فلو أتوقف الإنسان عن شرب الكحول أو عن تناول
+
+495
+00:35:31,070 --> 00:35:35,010
+التدخين برجع الأمر لوضعه الطبيعي ولكن بعد فترة
+
+496
+00:35:35,010 --> 00:35:40,330
+زمنية معينة ال environment toxin المتعرض لها خاصة
+
+497
+00:35:40,330 --> 00:35:46,590
+ال pesticide والمواد الثقيلة والمواد الإشعاعيةبعض
+
+498
+00:35:46,590 --> 00:35:50,570
+الأحيان بيصنف بعض الحالات unexplained infertility
+
+499
+00:35:50,570 --> 00:35:54,310
+اديوباثيك يعني كله طبيعي مية في المية الإنتاج مية
+
+500
+00:35:54,310 --> 00:35:55,910
+في المية الهرمونات مية في المية ال reproductive
+
+501
+00:35:55,910 --> 00:35:58,630
+system مية في المية مافي عنده antiferrent body
+
+502
+00:35:58,630 --> 00:36:02,230
+مافي عنده ال percocial lifestyle مية في المية مافي
+
+503
+00:36:02,230 --> 00:36:05,490
+عنده مشكلة ولكن والجيلاتك برضه مافي عنده مشكلة
+
+504
+00:36:05,490 --> 00:36:09,570
+جينية أو مافي عنده مشكلة جينية ولكن يصنف infertile
+
+505
+00:36:09,570 --> 00:36:15,200
+تحت عنوان adiopathic infertility أوExcipline
+
+506
+00:36:15,200 --> 00:36:19,720
+Infertility يعني أسباب غير معروفة طبعا عندي
+
+507
+00:36:19,720 --> 00:36:24,280
+بالنسبة لل infertility cases .. courses عندي 30%
+
+508
+00:36:24,280 --> 00:36:28,660
+اللي لها علاقة بالمال عندي 30% اللي لها علاقة بال
+
+509
+00:36:28,660 --> 00:36:32,560
+female عندي 10% اللي لهم علاقة بال male و female
+
+510
+00:36:32,560 --> 00:36:38,480
+25% تعتبر idiopathic و 5% غير معروفين حتى مش
+
+511
+00:36:38,480 --> 00:36:42,740
+مصنفين ك idiopathic بدي أنا قبل ما أختم هذه
+
+512
+00:36:42,740 --> 00:36:46,850
+المحاضرةبدي أحكي ببساطة جدا أن كمية و نسبة ال
+
+513
+00:36:46,850 --> 00:36:51,330
+infertility في الواقع اللي بيعيش في قطاع غزة زادت
+
+514
+00:36:51,330 --> 00:36:57,210
+بعد حرب 2008 بشكل ملحوظ جدا بعد حرب 2012 and المية
+
+515
+00:36:57,210 --> 00:37:00,510
+طبعا بعد حرب 2012 صار and the recurrent abortion
+
+516
+00:37:00,510 --> 00:37:06,870
+بشكل ملحوظ جدا وصوصا عند سكان المناطق الحدودية
+
+517
+00:37:06,870 --> 00:37:09,950
+سواء المناطق الشرقية أو المناطق الشمالية قد يكون
+
+518
+00:37:09,950 --> 00:37:14,440
+له علاقةوقد يكون .. وقد لا يكون له علاقة بمخلفات
+
+519
+00:37:14,440 --> 00:37:18,280
+الحروب هذا بيحتاج إلى دراسة ولكن ما تم لمسه على
+
+520
+00:37:18,280 --> 00:37:21,600
+أرض الواقع أن ال male infertility زادت بعد حرب
+
+521
+00:37:21,600 --> 00:37:26,540
+2008 و ال miscarriage أو ال recurrent abortion أو
+
+522
+00:37:26,540 --> 00:37:31,560
+التشوهات الجنينية التي تظهر على الأجنة بعد عملية
+
+523
+00:37:31,560 --> 00:37:34,800
+ال miscarriage أو بعد عملية ال abortion كانت عالية
+
+524
+00:37:34,800 --> 00:37:40,580
+بعد حرب 2012 في المناطق القدودية الشرقية والشمالية
+
+525
+00:37:40,830 --> 00:37:44,530
+سوف نكتفي بهذا القدر في محاضرة اليوم، على أمل أن
+
+526
+00:37:44,530 --> 00:37:48,290
+نستكمل في المحاضرة التالية تحت عنوان Primary
+
+527
+00:37:48,290 --> 00:37:53,470
+Fertility and Secondary Infertility، دمتم في حفظ
+
+528
+00:37:53,470 --> 00:37:54,570
+الله ورياه حياتي
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/DYESKICx4QA_postprocess.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/DYESKICx4QA_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..df7581d08b490ae9c14151d24be94471f5d8b2ef
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/DYESKICx4QA_postprocess.srt
@@ -0,0 +1,1680 @@
+1
+00:00:00,770 --> 00:00:04,450
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:04,450 --> 00:00:09,830
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا
+
+3
+00:00:09,830 --> 00:00:14,270
+العزاء أرجو من الله أن تكونوا بخير استكمالا لما
+
+4
+00:00:14,270 --> 00:00:17,930
+بدأنا فيه من محاضرة sperm assessment processing
+
+5
+00:00:17,930 --> 00:00:22,230
+and selection تحدثنا عن عدة أمور لها علاقة بال
+
+6
+00:00:22,230 --> 00:00:25,170
+macroscopic examination وmicroscopic examination
+
+7
+00:00:25,870 --> 00:00:29,110
+وفي النهاية، تحدثنا عن الـVatility Test أو الـLife
+
+8
+00:00:29,110 --> 00:00:33,450
+Sperm Examination من خلال فحص الأيوزين أو
+
+9
+00:00:33,450 --> 00:00:38,150
+النجروسين استثنى استكمال لهذا الأمر، سوف نتكلم عن
+
+10
+00:00:38,150 --> 00:00:41,610
+الـHoss Test أو ما يُعرف باسم الـHypoosmotic
+
+11
+00:00:41,610 --> 00:00:45,770
+Swelling Test الـHypoosmotic Swelling Test، اختصار
+
+12
+00:00:45,770 --> 00:00:50,910
+Hoss Test وهو عبارة عن فحص يُستخدم للتفريغ ما بين
+
+13
+00:00:50,910 --> 00:00:56,570
+الحيوان المنوي الحيوالحيوان المنوي الميت وهو كفحص
+
+14
+00:00:56,570 --> 00:01:00,850
+مهم جدا خلال عملية ال fertilization لإنه أنا بهمني
+
+15
+00:01:00,850 --> 00:01:05,590
+أحقن الخلية بحيوان منوي حي حتى لو كان مش متحرك
+
+16
+00:01:05,590 --> 00:01:10,890
+فالمهم أن يكون حي The principle only living cell
+
+17
+00:01:10,890 --> 00:01:14,590
+with intact membrane will swell under hypoosmotic
+
+18
+00:01:14,590 --> 00:01:20,530
+condition 150 mO·L يعني المبدأ عمل هذا الفحص إن
+
+19
+00:01:20,530 --> 00:01:25,960
+الخلايا الحيةتميل إلى الـ swelling في حالة تعرضها
+
+20
+00:01:25,960 --> 00:01:30,480
+إلى الـ hypo osmotic condition يعني أنا أي خلية
+
+21
+00:01:30,480 --> 00:01:34,400
+حاططها في hypo osmotic condition هتنتفخ وهذه نفس
+
+22
+00:01:34,400 --> 00:01:39,360
+الفكرة في الـ host test أو الـ hypo osmotic
+
+23
+00:01:39,360 --> 00:01:44,540
+swelling the influx of a fluid into via pedicel is
+
+24
+00:01:44,540 --> 00:01:49,020
+reflected by the coiling of the sperm يعني ال
+
+25
+00:01:49,020 --> 00:01:53,080
+sperm إذا كان هذا ال sperm حيوضعته في hypo-osmotic
+
+26
+00:01:53,080 --> 00:01:57,640
+swelling or solution مباشرة، نهاية التل الخاصة فيه
+
+27
+00:01:57,640 --> 00:02:02,200
+هتنتفخ، معناه إن والله هذا ال sperm life، هذا ال
+
+28
+00:02:02,200 --> 00:02:07,660
+sperm available or lifeأحد أفضلات هذا الاختبار هو
+
+29
+00:02:07,660 --> 00:02:13,460
+أنه لا يقتل الفحص الذي يسمح بالتوليجة لهذا الفحص
+
+30
+00:02:13,460 --> 00:02:18,500
+للتكنولوجيا التجاربية يعني بمعنى أخر أن هذا الفحص
+
+31
+00:02:18,500 --> 00:02:21,480
+ما بيأثر على الفحص ما بيأثر على المادة الوراثية
+
+32
+00:02:21,480 --> 00:02:24,240
+بتاعة الفحص ما بيأثر على الـ function بتاعة الفحص
+
+33
+00:02:24,240 --> 00:02:28,640
+ما بيأثر على الكبسط بتاعة الفحص فبالتالي أي فحص
+
+34
+00:02:28,640 --> 00:02:32,600
+أخضعته لهذه العملية واتضح فيما بعد أن الـ life
+
+35
+00:02:32,600 --> 00:02:39,220
+ممكن أن أستخدمه في الـ Xبشكل مباشر بدون أي تردد In
+
+36
+00:02:39,220 --> 00:02:42,100
+this method, sperm sample should be mixed with the
+
+37
+00:02:42,100 --> 00:02:46,660
+hypoosmotic solution and incubated at 37 Celsius
+
+38
+00:02:46,660 --> 00:02:50,700
+for 30 minutes عشان انا اتأكد هذا ال sperm alive
+
+39
+00:02:50,700 --> 00:02:54,320
+ولا لا طب اذا كانت العينة بتستخدمها للإكزي يكفي
+
+40
+00:02:54,320 --> 00:02:59,910
+خمس دقائق تحضيرها بال hypoosmotic solutionبعد
+
+41
+00:02:59,910 --> 00:03:05,930
+عملية أحضين على 37 درجة مئوية لمدة 30 دقيقة أو
+
+42
+00:03:05,930 --> 00:03:11,150
+لمدة 5 دقائق باجي بعمل check up لل sperm أو بعد ال
+
+43
+00:03:11,150 --> 00:03:16,070
+sperm بعمل with preparation على ال slide should be
+
+44
+00:03:16,070 --> 00:03:19,170
+made and assess the sample under phase contrast
+
+45
+00:03:19,170 --> 00:03:23,630
+microscope على عدسة تكبير 400 أو 200 بعيد 200
+
+46
+00:03:23,630 --> 00:03:28,330
+sperm بشوف مين فيهم life و مين فيهم deadبناء على
+
+47
+00:03:28,330 --> 00:03:34,450
+الانتفاخ اللي يظهر أسفل الذئب في هذا الشكل طبعا دي
+
+48
+00:03:34,450 --> 00:03:37,890
+اللي على اليسار رقم A هي عبارة عن ال fertility
+
+49
+00:03:37,890 --> 00:03:42,590
+test بفعل النجروسين أو ال Iosin بضيف I قطرة من ال
+
+50
+00:03:42,590 --> 00:03:46,170
+Iosin بضيف قطرة من النجروسين و بضيف قطرة من السيمن
+
+51
+00:03:46,170 --> 00:03:50,450
+بعمله mix او واحد سيمن اتنين drop Iosin اتنين drop
+
+52
+00:03:50,450 --> 00:03:54,170
+نجروسين بعمل mix و بشوفها تحت الميكروسكوب اللي
+
+53
+00:03:54,170 --> 00:04:00,980
+بالشب هو ال lifeأما الأخر صفقة الـ Iosin هو الـ
+
+54
+00:04:00,980 --> 00:04:05,340
+dead أو الـ non-viable اللي على اليسار هي عبارة عن
+
+55
+00:04:05,340 --> 00:04:09,700
+الـ hypo osmotic swelling test الـ host test بضيف
+
+56
+00:04:09,700 --> 00:04:14,140
+sample من الـ seminal fluid بضيف عليه الـ hypo
+
+57
+00:04:14,140 --> 00:04:18,180
+osmotic swelling fluid or solution وبعمل mixing
+
+58
+00:04:18,180 --> 00:04:24,900
+وincubation لمدة 30 أو 5 دقائقعلى 37 درجة مهوية أي
+
+59
+00:04:24,900 --> 00:04:29,440
+sperm بظهر لـ swelling في أسفله هذا معناه normal
+
+60
+00:04:29,440 --> 00:04:32,280
+sperm swelling زي ما أحنا شايفينه على جهة اليسار
+
+61
+00:04:32,280 --> 00:04:36,840
+في منطقة التل بسميه normal sperm viable sperm أما
+
+62
+00:04:36,840 --> 00:04:39,800
+إذا كان مافيه swelling في نهاية التل فهو عبارة عن
+
+63
+00:04:39,800 --> 00:04:45,420
+non viable sperm أو dead sperm هذا الفرق ما بين
+
+64
+00:04:45,420 --> 00:04:50,220
+الفرقتانفي طريقة تانية وهي طريقة العدو معتمدة على
+
+65
+00:04:50,220 --> 00:04:54,480
+الكمبيوتر بنسميها Computerized
+
+66
+00:04:54,480 --> 00:05:00,560
+Assisted Sperm Analysis أو Computer Assisted Sperm
+
+67
+00:05:00,560 --> 00:05:07,840
+Analysis تحت مصطلح كذا كذا C للكمبيوتر A Assisted
+
+68
+00:05:07,840 --> 00:05:12,940
+Sperm Analysis يعني أنت كتكنيشن ما بتشتغل شيء إلا
+
+69
+00:05:12,940 --> 00:05:16,360
+بتعمل weight mount يعني كتانك تضيف خمسين micro من
+
+70
+00:05:16,730 --> 00:05:19,590
+عينة الـ Similar Fluid بعد الـ mix الجيد و بتغطيها
+
+71
+00:05:19,590 --> 00:05:22,930
+بـ cover slide و بتدخلها تحت ال microscope و ال
+
+72
+00:05:22,930 --> 00:05:26,550
+microscope بناء على software معين بيقرأ كل ال
+
+73
+00:05:26,550 --> 00:05:29,870
+field بيهدلك ال sperm و بيجيبلك ال motility و
+
+74
+00:05:29,870 --> 00:05:34,130
+بيجيبلك ال morphology حتى بيجيبلك تصنيف ال motile
+
+75
+00:05:34,130 --> 00:05:37,830
+هى ال progressive و لا non progressive motile ولكن
+
+76
+00:05:37,830 --> 00:05:42,410
+خد بالك أنه لازمبنعمل check-up على نتائجه لأن في
+
+77
+00:05:42,410 --> 00:05:47,270
+نسبة خطأ منها بفعل أن بعض الـ Depress ممكن يعدها ك
+
+78
+00:05:47,270 --> 00:05:56,030
+Spare خلينا نشوف الفيديو متعلق بعد الموضوع نشوف
+
+79
+00:05:56,030 --> 00:05:59,030
+الفيديو Motility and concentration sample
+
+80
+00:05:59,030 --> 00:06:03,290
+preparation First step is to prepare a sample for
+
+81
+00:06:03,290 --> 00:06:05,410
+motility and concentration analysis
+
+82
+00:06:12,750 --> 00:06:13,950
+يمكن استخدام بطاريات مستخدمة يمكن استخدامها
+
+83
+00:06:13,950 --> 00:06:16,590
+بطاريات مستخدمة يمكن استخدامها بطاريات مستخدمة
+
+84
+00:06:16,590 --> 00:06:20,710
+يمكن استخدامها بطاريات مستخدمة يمكن استخدامها
+
+85
+00:06:20,710 --> 00:06:21,250
+بطاريات مستخدمة يمكن استخدامها بطاريات مستخدمة
+
+86
+00:06:21,250 --> 00:06:23,670
+يمكن استخدامها بطاريات مستخدمة يمكن استخدامها
+
+87
+00:06:23,670 --> 00:06:27,550
+بطاريات مستخدمة يمكن استخدامها بطاريات مستخدمة
+
+88
+00:06:27,550 --> 00:06:29,270
+يمكن استخدامها بطاريات مستخدمة يمكن استخدامها
+
+89
+00:06:29,270 --> 00:06:31,470
+بطاريات مستخدمة يمكن استخدامها بطاريات مستخدمة
+
+90
+00:06:31,470 --> 00:06:36,270
+يمكن استخدامها بطاريات مستخدمة يمكن استخ
+
+91
+00:06:40,810 --> 00:06:45,450
+ثم إزالة المواصفات المكسورة السلسلة مستعدة للتعامل
+
+92
+00:06:45,450 --> 00:06:50,150
+معها مقاطع الميكروسكوبللتحديث الموتولوجيا
+
+93
+00:06:50,150 --> 00:06:54,150
+والتركيزية سنستخدم الـ Green Filter، الـ Condenser
+
+94
+00:06:54,150 --> 00:06:59,490
+في موقع PH1 و10X Face Consciousness Objective تذكر
+
+95
+00:06:59,490 --> 00:07:02,650
+أنه ممكن أيضًا أن تستخدم الـ Fluorescence
+
+96
+00:07:02,650 --> 00:07:06,870
+موتولوجيا والتركيزية تستخدم الـ Fluorescence It is
+
+97
+00:07:06,870 --> 00:07:09,670
+possible to access the analysis module from the
+
+98
+00:07:09,670 --> 00:07:12,670
+respective button in results tab or from the icons
+
+99
+00:07:12,670 --> 00:07:16,810
+bar In this window, the user can choose different
+
+100
+00:07:16,810 --> 00:07:20,760
+analysis configurationsThis is the main analysis
+
+101
+00:07:20,760 --> 00:07:23,540
+window where the sample information is presented
+
+102
+00:07:23,540 --> 00:07:28,400
+Press analyze to start Live image is displayed
+
+103
+00:07:28,400 --> 00:07:34,420
+focus طبعا هنا ضاف العينة وشغل الميكروسكوب وعمل
+
+104
+00:07:34,420 --> 00:07:38,000
+analysis فجاب ال field أخد capture الميكروسكوب
+
+105
+00:07:38,000 --> 00:07:41,100
+فيما بعد ببدأ أو الكمبيوتر ببدأ يعد ال sperm
+
+106
+00:07:41,100 --> 00:07:47,140
+الموجودة في هذا ال capture بناء علىطبعاً عدد و
+
+107
+00:07:47,140 --> 00:07:53,220
+Parameter معينة و طول و عرض خاصة بالhead بعد كده
+
+108
+00:07:53,220 --> 00:07:55,600
+بياخد أكتر من ال capture و بيقارنهم مع بعض و مع
+
+109
+00:07:55,600 --> 00:08:00,740
+بعض علشان يشوف مين المتايل و مين المش متايل spare
+
+110
+00:08:00,740 --> 00:08:04,220
+fill and start the analysis clicking again the
+
+111
+00:08:04,220 --> 00:08:08,560
+analyze button main analysis information is always
+
+112
+00:08:08,560 --> 00:08:12,760
+present on this side or capture sequences can be
+
+113
+00:08:12,760 --> 00:08:17,250
+played in the analysis user tabباستخدام مانيال
+
+114
+00:08:17,250 --> 00:08:18,930
+النتائج، يمكن المستخدم أن يختار مقاطع الـSperm
+
+115
+00:08:18,930 --> 00:08:22,830
+مختلفة ويقوم بمعرفة أو لا معرفة أي Spermatozoa تم
+
+116
+00:08:22,830 --> 00:08:25,850
+إظهارها
+
+117
+00:08:25,850 --> 00:08:33,950
+.من
+
+118
+00:08:33,950 --> 00:08:36,790
+الممكن أيضًا أن تشاهد المعلومات عن واحدة Sperm
+
+119
+00:08:36,790 --> 00:08:42,260
+بمضغط عينيها وفتح مقاطع الـSperm Infoبنقل إلى
+
+120
+00:08:42,260 --> 00:08:44,100
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+121
+00:08:44,100 --> 00:08:46,600
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+122
+00:08:46,600 --> 00:08:49,960
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+123
+00:08:49,960 --> 00:08:55,400
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+124
+00:08:55,400 --> 00:08:55,500
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+125
+00:08:55,500 --> 00:08:55,600
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+126
+00:08:55,600 --> 00:09:05,720
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+127
+00:09:05,720 --> 00:09:10,080
+نتيج
+
+128
+00:09:10,580 --> 00:09:13,360
+أتابع مع المعلومات عن مصادرها الـ Spermatozoon
+
+129
+00:09:13,360 --> 00:09:28,380
+وخلاصًا
+
+130
+00:09:28,380 --> 00:09:32,040
+مصادر تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+131
+00:09:32,040 --> 00:09:33,260
+تجارب تجارب تجارب
+
+132
+00:09:41,070 --> 00:09:44,770
+هو بسهولة جدًا للوصول إلى مقال التجارب اللي يمكن
+
+133
+00:09:44,770 --> 00:09:55,650
+أن يتم تحميله لأي مصمم التجارب التجاربية
+
+134
+00:09:55,650 --> 00:09:57,210
+يمكن أن يتم تحميله لأي مصمم التجارب التجاربية
+
+135
+00:09:57,210 --> 00:10:00,650
+التجاربية يمكن أن يتم تحميله لأي مصمم التجارب
+
+136
+00:10:00,650 --> 00:10:02,630
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+137
+00:10:02,630 --> 00:10:03,230
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+138
+00:10:03,230 --> 00:10:03,310
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+139
+00:10:03,310 --> 00:10:03,710
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+140
+00:10:03,710 --> 00:10:09,650
+التجاربية التجاربية التجاربية التجاربية التجارب
+
+141
+00:10:14,380 --> 00:10:18,700
+إذا هذه فكرة الكازة و هي ال computer assist sperm
+
+142
+00:10:18,700 --> 00:10:22,200
+analysis إنه أنا ك technician ما بشغل شيء بيدي و
+
+143
+00:10:22,200 --> 00:10:25,320
+جرد إن بحضر ال sample من خلال وضع خمسين micro أو
+
+144
+00:10:25,320 --> 00:10:28,740
+عشرة micro بناء على ال protocol المستخدم و بعدين
+
+145
+00:10:28,740 --> 00:10:31,220
+بضيفه تحت ال fluorescent microscope أو ال face
+
+146
+00:10:31,220 --> 00:10:34,840
+contrast microscope على عدسة عشرة بعدين بعمل
+
+147
+00:10:34,840 --> 00:10:38,640
+switch on للجهاز و بخليه ياخد capture و 2 و 3 و 4
+
+148
+00:10:39,000 --> 00:10:42,500
+بعدين بدأت على ال analysis عشان يبدأ الجهاز يحلل
+
+149
+00:10:42,500 --> 00:10:46,100
+الصور اللي أخدهم أكتر من مرة بيديني ال utility،
+
+150
+00:10:46,100 --> 00:10:48,520
+بيديني أنواعها، بيديني ال concentration، بيديني ال
+
+151
+00:10:48,520 --> 00:10:51,540
+total count، بيديني ال morphology، بناء على شو أنا
+
+152
+00:10:51,540 --> 00:10:54,720
+بدي براميتر كلها متوفرة، بناء على ال program
+
+153
+00:10:54,720 --> 00:10:59,130
+المستخدم، كل شركة لها program خاص فيهاخدوا بالكوا
+
+154
+00:10:59,130 --> 00:11:03,030
+الكازم ما بيستخدم في الـ routine lab أو اللي بيقول
+
+155
+00:11:03,030 --> 00:11:06,790
+كمية العيلة بتجي لها خمسة، ستة، سبعة، تمانية في
+
+156
+00:11:06,790 --> 00:11:12,030
+اليوم لأ بيستخدم في المختبرات الكبيرة اللتي يوجد
+
+157
+00:11:12,030 --> 00:11:16,190
+عندها ضغط كبير من العمل أو مختبرات اللي لها علاقة
+
+158
+00:11:16,190 --> 00:11:20,370
+بال research المتعلق في ال anthropology هذه فكرة
+
+159
+00:11:20,370 --> 00:11:25,470
+الكازم الفكرة التانية اللي بتتكلم عنها كيف تعمل
+
+160
+00:11:25,470 --> 00:11:29,850
+evaluation لل sperm DNAطبعا ال sperm اعرفته انه
+
+161
+00:11:29,850 --> 00:11:33,590
+life ال sperm اعرفته انه motile هل ال sperm DNA
+
+162
+00:11:33,590 --> 00:11:37,710
+جيد فيه damage في ال sperm DNA لأنه ممكن ال sperm
+
+163
+00:11:37,710 --> 00:11:43,210
+يكون motile ويكون life ولكن ال capacity تبعته مش
+
+164
+00:11:43,210 --> 00:11:47,350
+هال capacity و ال DNA تبعته صار فيها fragmentation
+
+165
+00:11:47,350 --> 00:11:50,790
+فبالتالي لو عمل fertilization ممكن يؤدي إلى إجهاض
+
+166
+00:11:50,790 --> 00:11:56,480
+الجنيه لأنه ما ارتقى إلىالكيف والكم المناسب لإتمام
+
+167
+00:11:56,480 --> 00:12:00,180
+عملية ال fertilization بالشكل المطلوب تحت مصطلح
+
+168
+00:12:00,180 --> 00:12:03,680
+evaluation of sperm DNA damage the maintenance of
+
+169
+00:12:03,680 --> 00:12:08,160
+sperm DNA integrity is vital for fertilized and to
+
+170
+00:12:08,160 --> 00:12:10,440
+transmitted the genetic material from one
+
+171
+00:12:10,440 --> 00:12:13,880
+generation to another لأن المادة الوراثية هي عبارة
+
+172
+00:12:13,880 --> 00:12:18,800
+عن جوهر العملية ال fertilization تصير عشان ينقل
+
+173
+00:12:18,800 --> 00:12:23,350
+المادة النووية الخاصة بالأب إلىالمادة النووية
+
+174
+00:12:23,350 --> 00:12:26,810
+الخاصة بالقمج تكوين الزيجوت إذا كان هذا المادة
+
+175
+00:12:26,810 --> 00:12:29,550
+النووية فيها مشكلة معناه الزيجوت اللي اتكوّنت
+
+176
+00:12:29,550 --> 00:12:34,310
+حتصير فيها مشكلة معناه فرصة ال up portion هتزيد ال
+
+177
+00:12:34,310 --> 00:12:37,850
+sperm chromatin undergoes extensive remodeling
+
+178
+00:12:37,850 --> 00:12:43,430
+during spermatogenesis to protect sperm DNA بمعنى
+
+179
+00:12:43,430 --> 00:12:46,590
+آخر إن هذا ال DNA الموجود داخل ال sperm في ال head
+
+180
+00:12:46,590 --> 00:12:50,450
+تاع ال sperm فيه عند ال chromatinالقرمتين الموجود
+
+181
+00:12:50,450 --> 00:12:53,970
+هناك بيصير له عملية كبيرة جدا من الـ remedulling
+
+182
+00:12:53,970 --> 00:12:58,050
+علشان يحافظ على ال sperm و يحمل مادة نوية لخاصة
+
+183
+00:12:58,050 --> 00:13:02,690
+بال sperm من التكسير أو من التلف إذا ما صارش إلها
+
+184
+00:13:02,690 --> 00:13:06,130
+remedulling معناه فيه defect حيصير على صعيد ال
+
+185
+00:13:06,130 --> 00:13:10,410
+sperm DNA in this process most of sperm DNA
+
+186
+00:13:10,410 --> 00:13:14,610
+hostone should be replaced with protamine Iو
+
+187
+00:13:14,610 --> 00:13:19,050
+البروتامين 2 و كمية صغيرة من البروتامين يجب أن
+
+188
+00:13:19,050 --> 00:13:24,530
+تبقى موجودة في الديانة، في المبالغة هذه العملية
+
+189
+00:13:24,530 --> 00:13:27,550
+مهمة جدا أنه إذا كان عندك كمية كبيرة جدا من
+
+190
+00:13:27,550 --> 00:13:31,550
+البروتامين كبروتين هذا البروتامين سوف يستبدل
+
+191
+00:13:31,550 --> 00:13:35,790
+بالبروتامين 1 وبروتامين 2 و لازم ما يتبقى من
+
+192
+00:13:35,790 --> 00:13:40,310
+البروتامين إلا كمية قليلة جدا جدا جدا لو لم تحدث
+
+193
+00:13:40,310 --> 00:13:44,760
+هذه العملية عملية البروتامين replacementهيكون فيه
+
+194
+00:13:44,760 --> 00:13:47,800
+end effect في الـ structure of DNA في الـ
+
+195
+00:13:47,800 --> 00:13:50,720
+spermatogenesis، معناه الـ sperm لن يؤدي الوظيفة
+
+196
+00:13:50,720 --> 00:13:55,140
+المطلوبة منه if this event don't occur probably
+
+197
+00:13:55,140 --> 00:13:58,240
+endospermatozoa will retain more or save more
+
+198
+00:13:58,240 --> 00:14:01,460
+histone than they should sperm DNA become more
+
+199
+00:14:01,460 --> 00:14:04,060
+sensitive to damaging هذا الكلام اللي حكيته قبل
+
+200
+00:14:04,060 --> 00:14:07,560
+بشوية إنه يجب أن تتم عملية استبدال الهستون
+
+201
+00:14:07,560 --> 00:14:11,300
+بالبروتامين 1 وبروتامين 2 ويبقى الهستون بكمية
+
+202
+00:14:11,300 --> 00:14:14,830
+قليلة جدا جدا جدا داخل ال spermإذا لم تحدث هذه
+
+203
+00:14:14,830 --> 00:14:18,450
+العملية، معناه إن الـDNA الموجود داخل الـSperm
+
+204
+00:14:18,450 --> 00:14:23,230
+هيكون أكثر حساسية للتلف والتكسير طيب، شو اللي
+
+205
+00:14:23,230 --> 00:14:27,250
+هيكسر؟ وشو هيخليه عرض للتلف؟ بقول الـDNA الـdamage
+
+206
+00:14:27,250 --> 00:14:31,090
+can occur only during spermatogenesis أكيد، but
+
+207
+00:14:31,090 --> 00:14:35,610
+also during storage in epidermis or transport from
+
+208
+00:14:35,610 --> 00:14:39,310
+one place to another يعني معنى آخر إن الـSperm
+
+209
+00:14:39,310 --> 00:14:43,950
+طالما خُلقولم يحدث له عن أي مشكلة خلال عمل التخليق
+
+210
+00:14:43,950 --> 00:14:49,470
+أنه بيكون فيه أمان وفيه مكان مأمون عن المخاطر لأ
+
+211
+00:14:49,470 --> 00:14:53,150
+ممكن يتعرض إلى external factor أو another factor
+
+212
+00:14:53,150 --> 00:14:56,330
+خلال عملية التخزين في الepidermis أو خلال عملية ال
+
+213
+00:14:56,330 --> 00:14:59,650
+ejaculation أو خلال ال transfer من منطقة إلى منطقة
+
+214
+00:14:59,650 --> 00:15:04,020
+يودي إلى تلفد يعنيمن أشهر العوامل التي تؤدي إلى
+
+215
+00:15:04,020 --> 00:15:07,460
+DNA damage هي عبارة عن Oxidative Stress اللي
+
+216
+00:15:07,460 --> 00:15:11,680
+بتسميه OS شو يعني Oxidative Stress؟ ببساطة في
+
+217
+00:15:11,680 --> 00:15:15,160
+أجسامنا في حاجة اسمها Free Radical وفي حاجة اسمها
+
+218
+00:15:15,160 --> 00:15:18,020
+Antioxidant لازم يصير فيه balance ما بين ال
+
+219
+00:15:18,020 --> 00:15:23,200
+antioxidantو ال free radical إذا صار في عندي
+
+220
+00:15:23,200 --> 00:15:26,200
+imbalance ما بين ال free radical و ال antioxidant
+
+221
+00:15:26,200 --> 00:15:30,520
+حيصير عندي حالة بنسميها oxidative stress oxidative
+
+222
+00:15:30,520 --> 00:15:33,460
+stress is one of the most common intrinsic factors
+
+223
+00:15:33,460 --> 00:15:37,640
+leading to sperm DNA damage but it may also result
+
+224
+00:15:37,640 --> 00:15:42,440
+from pathogenic status of the reproductive system
+
+225
+00:15:42,440 --> 00:15:48,610
+برجع بقول مرة تانيةالـ Oxidative Stress ينتج من
+
+226
+00:15:48,610 --> 00:15:52,750
+خلال عدم وجود اتزان ما بين كمية الـ Antioxidant
+
+227
+00:15:52,750 --> 00:15:56,890
+الموجودة في أجسامنا و الـ Free Radical و الأكتر
+
+228
+00:15:56,890 --> 00:16:01,590
+تخصيص عدم وجود اتزان ما بين كمية الـ Antioxidant و
+
+229
+00:16:01,590 --> 00:16:04,470
+الـ Free Radical الموجودة في سمن الفلويد فواحد
+
+230
+00:16:04,470 --> 00:16:08,310
+بزيد عن التاني هيعطيني Oxidative Stress Oxidative
+
+231
+00:16:08,310 --> 00:16:12,620
+Stress يعتبر من أشهر وأكترالأسباب المسببة إلى
+
+232
+00:16:12,620 --> 00:16:16,800
+تكسير و تلف المادة الوراطية الخاصة بالـ sperm ولكن
+
+233
+00:16:16,800 --> 00:16:21,940
+هناك عوام الأخرى لها علاقة بالأمراض المتعلقة بالـ
+
+234
+00:16:21,940 --> 00:16:28,680
+Mere Reproductive System حوالي 25% زيادة من الـ
+
+235
+00:16:28,680 --> 00:16:33,940
+reactive oxidase species اللي سمنها free radical
+
+236
+00:16:33,940 --> 00:16:38,030
+25% increase in seminalمعنى الـ Reactive Oxygen
+
+237
+00:16:38,030 --> 00:16:43,070
+Species Level مرتبط بـ 10% تزيد في عدد الـ Sperm
+
+238
+00:16:43,070 --> 00:16:47,190
+DNA Fragmentation يعني عندي لو زاد الـ Reactive
+
+239
+00:16:47,190 --> 00:16:53,050
+Oxygen Species اللي سميتها Free Radical 25% ستكون
+
+240
+00:16:53,050 --> 00:16:59,970
+سبب في تدمير 10% من الـ Sperm DNA تحت مصطلح DNA
+
+241
+00:16:59,970 --> 00:17:04,790
+Fragmentation بمعدل 10% DNA Damage can affect both
+
+242
+00:17:04,790 --> 00:17:09,940
+Nuclear DNAوMitochondrial DNA يعني بمعنى آخر أن
+
+243
+00:17:09,940 --> 00:17:13,760
+الـ Oxidative Stress لن يؤثر فقط على الـ Nucleic
+
+244
+00:17:13,760 --> 00:17:16,500
+Acid الموجود في الـ head، في الـ Nuclear ولكن
+
+245
+00:17:16,500 --> 00:17:19,040
+هيؤثر أيضًا على الـ Nucleic Acid الموجود في الـ
+
+246
+00:17:19,040 --> 00:17:23,300
+Mitochondria Oxidative Stress induced damage to
+
+247
+00:17:23,300 --> 00:17:27,180
+Nuclear DNA may accelerate germ cell apoptosis
+
+248
+00:17:27,180 --> 00:17:30,300
+leading to decline in sperm production and
+
+249
+00:17:30,300 --> 00:17:35,080
+consequently decrease sperm count in ejaculationلو
+
+250
+00:17:35,080 --> 00:17:38,440
+حصل فيه stress إكسيداتيه سيدمر ال DNA الموجودة في
+
+251
+00:17:38,440 --> 00:17:42,120
+نوات ال sperm فبالتالي سيسرق تواجه ال sperm إلى
+
+252
+00:17:42,120 --> 00:17:46,120
+Epiptosis معناه سيصير نقصان في عدد ال sperm
+
+253
+00:17:46,120 --> 00:17:50,760
+الموجود في ال ejaculation معناه في عندي ببساطة جدا
+
+254
+00:17:50,760 --> 00:17:54,640
+نقصان في كمية ال sperm المخلق معناه في عندي نقصان
+
+255
+00:17:54,640 --> 00:17:58,780
+في ال sperm count يعني one step another step go to
+
+256
+00:17:58,780 --> 00:18:02,080
+another step a positive sum study
+
+257
+00:18:13,420 --> 00:18:18,640
+معناه زيادة الـ sperm DNA fragmentation متعلق
+
+258
+00:18:18,640 --> 00:18:22,440
+بزيادة الـ abnormal في الـ sperm morphology و
+
+259
+00:18:22,440 --> 00:18:26,820
+بالذات في الـ sperm تاني في دراسة أخرى قالت إنه في
+
+260
+00:18:26,820 --> 00:18:30,800
+عندي higher incidence of aneuploidy in manin men
+
+261
+00:18:30,800 --> 00:18:34,520
+or males with high spare DNA fragmentation ال
+
+262
+00:18:34,520 --> 00:18:40,120
+incidence تبع الانبلويدي في الذكور بيزيد لو زاد
+
+263
+00:18:40,120 --> 00:18:46,160
+عندي ال DNA fragmentation هذه شكل أخر ودراسة أخرى
+
+264
+00:18:46,160 --> 00:18:50,800
+وجدت أن ال higher incidence of anibluity في الذكور
+
+265
+00:18:50,800 --> 00:18:58,480
+مرتبط بالhigh spare DNA fragmentation صورة بتوضح
+
+266
+00:18:58,480 --> 00:19:02,580
+الكلام اللي اتكلمنا عنههذا الـ sperm في أعلى الـ
+
+267
+00:19:02,580 --> 00:19:06,000
+slide sperm، normal sperm بيصيرله capacitation
+
+268
+00:19:06,000 --> 00:19:09,260
+بيصير عندي acrosome reaction بيصير عندي
+
+269
+00:19:09,260 --> 00:19:12,880
+hyperactivation يعني بيصير عندي fertilization ما
+
+270
+00:19:12,880 --> 00:19:15,960
+بيصير fertilization إلا إذا صارت capacitation وهو
+
+271
+00:19:15,960 --> 00:19:19,900
+تحول ال sperm إلى completely mature sperm بعدين
+
+272
+00:19:19,900 --> 00:19:23,960
+بيصير acrosome reaction من خلال اتصال ال sperm مع
+
+273
+00:19:23,960 --> 00:19:26,440
+الـ receptor الموجودة في الزنا باليسود رقم 3
+
+274
+00:19:26,440 --> 00:19:30,430
+وإفراز إنزيماته الهاضمةبعدين بيصير الـ
+
+275
+00:19:30,430 --> 00:19:33,950
+hyperactivation و هي عبارة عن زيادة الحركة مما
+
+276
+00:19:33,950 --> 00:19:36,630
+يسمح للـ sperm باختراق الـ void بتصير
+
+277
+00:19:36,630 --> 00:19:40,510
+fertilization تصور صار عندك imbalance ما بين الـ
+
+278
+00:19:40,510 --> 00:19:43,710
+free radical reactive oxygen species و ال
+
+279
+00:19:43,710 --> 00:19:47,790
+antioxidant هتعطيلي حالة بنسميها oxidative stress
+
+280
+00:19:47,790 --> 00:19:51,570
+هذا ال oxidative stress مصدرها قد يكون أسبابها
+
+281
+00:19:51,570 --> 00:19:55,830
+خارجية زي ال smoking زي ال radiation زي الكحول و
+
+282
+00:19:55,830 --> 00:19:59,400
+زي المواد التكسيديةوقد تكون داخلية زي الـ
+
+283
+00:19:59,400 --> 00:20:04,060
+Varicosel دوال الخصية زي الـ Leukocyte زيادة في
+
+284
+00:20:04,060 --> 00:20:06,700
+عدد Leukocyte يعني الـ inflammation وزي ال
+
+285
+00:20:06,700 --> 00:20:11,600
+immature spermatozoa خدوا بالكم النقطة التهاب
+
+286
+00:20:11,600 --> 00:20:16,460
+وزيادة عدد الحيوانات المنوية الغير ناضجة يؤدي إلى
+
+287
+00:20:16,460 --> 00:20:20,080
+زيادة عدد الرُس زيادة عدد الرُس تعتبر من أهم
+
+288
+00:20:20,080 --> 00:20:23,840
+العوامل التي تؤدي إلى الـ oxidative stress طب صار
+
+289
+00:20:23,840 --> 00:20:27,890
+في oxidative stress إيش هيسوي؟هيعمل على تعطيل الـ
+
+290
+00:20:27,890 --> 00:20:31,410
+physiological rules الخاصة بالـ sperm هتعطل
+
+291
+00:20:31,410 --> 00:20:34,810
+الcapacitation، هتعطل الacrosome reaction، هتعطل
+
+292
+00:20:34,810 --> 00:20:38,070
+الhyperactivity، يعني مافيه fertilization أضف إلى
+
+293
+00:20:38,070 --> 00:20:42,310
+ذلك، هتعمل apoptosis، هتعمل DNA damage على صحيح
+
+294
+00:20:42,310 --> 00:20:47,590
+الـDNA، هتعمل مشاكل في الـ lipid protein الموجودة
+
+295
+00:20:47,850 --> 00:20:52,730
+في الـ peroxidation الخاصة بالـ sperm فبالتالي الـ
+
+296
+00:20:52,730 --> 00:20:57,070
+infertility بتكون أقرب في هذه الحالة إلى الذكورة
+
+297
+00:20:57,070 --> 00:21:01,030
+Alteration in mitochondria sperm DNA mainly led to
+
+298
+00:21:01,030 --> 00:21:04,470
+impaired mitochondrial function those resulting in
+
+299
+00:21:04,470 --> 00:21:08,030
+the homotility abnormality, hyperactivity
+
+300
+00:21:08,030 --> 00:21:11,310
+abnormality, inability to fertilization يعني بمعنى
+
+301
+00:21:11,310 --> 00:21:16,030
+أخر ليس الخطر مرتبط بالدمج في ال sperm nuclear DNA
+
+302
+00:21:16,510 --> 00:21:19,990
+ولكن لو حد رزد دمش في ال sperm يتقندر ال DNA، هذا
+
+303
+00:21:19,990 --> 00:21:22,670
+معناه هيوقف ال motility، هتكون ال motility غير
+
+304
+00:21:22,670 --> 00:21:28,610
+متكافئة، غير سليمة، غير صحيحة، غير مطلوبة ال
+
+305
+00:21:28,610 --> 00:21:32,570
+hyperactivity هيصير فيها defect، هيصير غير قادر
+
+306
+00:21:32,570 --> 00:21:35,970
+على ال fertilization زي ما شفنا في ال slide السابق
+
+307
+00:21:45,480 --> 00:21:54,500
+الفرصة اللي تبقى
+
+308
+00:21:54,500 --> 00:21:58,060
+محدودة
+
+309
+00:21:58,060 --> 00:22:01,000
+في الـ sperm DNA لإصلاح المزيد من المزيد من المزيد
+
+310
+00:22:01,000 --> 00:22:03,160
+من المزيد من المزيدو Damage في الـ DNA معناه
+
+311
+00:22:03,160 --> 00:22:06,260
+البروتينات الموجودة في الـ Spare هتفقد وظيفتها
+
+312
+00:22:06,260 --> 00:22:10,200
+معناه الـ Spare هيفقد وظيفته The available method
+
+313
+00:22:10,200 --> 00:22:13,280
+we can use it to detect the DNA damage
+
+314
+00:22:13,280 --> 00:22:17,080
+fragmentation or apoptosis عندي تلت طرق Measured
+
+315
+00:22:17,080 --> 00:22:22,400
+DNA damage by incorporating DNA probe Measured the
+
+316
+00:22:22,400 --> 00:22:26,580
+sensitivity of DNA to denaturationindirect
+
+317
+00:22:26,580 --> 00:22:30,300
+measures of level chromatin compaction هذه التلت
+
+318
+00:22:30,300 --> 00:22:34,640
+عوامل أساسية هناخد تنتين مهمين جدا و لازم يتم
+
+319
+00:22:34,640 --> 00:22:39,080
+إجراءهم في مراكز التوضيح الصناعي So what is the
+
+320
+00:22:39,080 --> 00:22:42,620
+type of DNA damage؟ according to the type بقدر
+
+321
+00:22:42,620 --> 00:22:46,380
+أحدد ال test أول حاجة DNA fragmentationوالـ DNA
+
+322
+00:22:46,380 --> 00:22:50,380
+Fragmentation في عوامل أخرى كثيرة تساهم فيه منها
+
+323
+00:22:50,380 --> 00:22:53,220
+الـ Intrinsic أو الـ Extrinsic Factor الـ
+
+324
+00:22:53,220 --> 00:22:56,600
+Intrinsic Factor التي تؤدي إلى DNA Fragmentation
+
+325
+00:22:56,600 --> 00:23:01,980
+والذي يعتبر أحد أنواع الـ DNA Damaged Epitosis and
+
+326
+00:23:01,980 --> 00:23:05,620
+Oxidative Stress وحكينا عنها الـ Defect في الـ
+
+327
+00:23:05,620 --> 00:23:08,140
+Protamination وهي عملية استبدال الـ stone
+
+328
+00:23:08,140 --> 00:23:13,220
+بالبروتامين لأن وجود البروتامين مهم جدا لحمايةDNA
+
+329
+00:23:13,220 --> 00:23:17,480
+of spermatozoa Insufficient chromatin remodeling
+
+330
+00:23:17,480 --> 00:23:20,780
+خلل في الـ spermatogenesis إذا الأربع عوامل
+
+331
+00:23:20,780 --> 00:23:26,400
+الأساسية تصنف intrinsic factor تعمل على و تساهم في
+
+332
+00:23:26,400 --> 00:23:30,420
+حدوث الـ DNA fragmentation الذي يعتبر أحد أنواع
+
+333
+00:23:30,420 --> 00:23:33,830
+الـ DNA damageالعوامل الأخرى بنسميها external
+
+334
+00:23:33,830 --> 00:23:38,530
+factors زي ال life style زي الـ diet و ال drug
+
+335
+00:23:38,530 --> 00:23:43,110
+consuming و ال tobacco، cigarette smoking، الشيشة،
+
+336
+00:23:43,110 --> 00:23:46,330
+ال advancing age زيادة العمر، ال environment
+
+337
+00:23:46,330 --> 00:23:50,770
+exposure زي ال pesticide و ال pollution، بعض ال
+
+338
+00:23:50,770 --> 00:23:53,430
+medical history زي ال inflammation و الفارقوسيل و
+
+339
+00:23:53,430 --> 00:23:58,420
+ال cancerدول الأربع يعتبروا external factor تساهم
+
+340
+00:23:58,420 --> 00:24:02,600
+في إحداث DNA fragmentation الذي يعتبر أحد أنواع
+
+341
+00:24:02,600 --> 00:24:08,360
+الـ DNA damage صورة بتوضح الكلام اللي احنا اتكلمنا
+
+342
+00:24:08,360 --> 00:24:14,220
+عنه في sperm and sperm DNA damage بيصير بفعل أول
+
+343
+00:24:14,220 --> 00:24:18,480
+حاجة ال aging advanced aging infection cancer
+
+344
+00:24:18,480 --> 00:24:24,360
+toxic material radiation pollutionCaffeine Intake
+
+345
+00:24:24,360 --> 00:24:30,100
+Body Mass Index Malnutrition Poor Diet Alcohol
+
+346
+00:24:30,100 --> 00:24:34,560
+Stress Smoking Increase in testicular temperature
+
+347
+00:24:34,560 --> 00:24:37,360
+و البركوسيلة عشان كده الناس اللي بتشتغل في المخابز
+
+348
+00:24:37,360 --> 00:24:40,520
+القديمة و الناس اللي بتشتغل في مصانع الاسفنج و
+
+349
+00:24:40,520 --> 00:24:43,560
+بتتعرض لكمية كبيرة جدا من الحرارة بتكون أقرب لل
+
+350
+00:24:43,560 --> 00:24:48,700
+infertility بفيها الحدوث اتدمج في ال DNA طبعا مهم
+
+351
+00:24:48,700 --> 00:24:52,640
+جدا نعرف على هذه العوامل اللي قسمها Intrinsic
+
+352
+00:24:52,860 --> 00:24:57,400
+وextrinsic factor أكثر انتشاراً الـextrinsic
+
+353
+00:24:57,400 --> 00:25:01,860
+factor هي الأكثر انتشارا من أشهر الفحوصات التي
+
+354
+00:25:01,860 --> 00:25:05,860
+يمكن أن تستخدم بتحديد الـDNA fragmentationهي عبارة
+
+355
+00:25:05,860 --> 00:25:09,400
+عن فحص بنسميه Tunnel فحص Tunnel هو عبارة عن
+
+356
+00:25:09,400 --> 00:25:12,800
+Microscopic Dediction للأبيبتوسس فحص Tunnel هو
+
+357
+00:25:12,800 --> 00:25:17,240
+عبارة عن Microscopic Dediction للأبيبتوسس شو ال
+
+358
+00:25:17,240 --> 00:25:21,320
+принцип الأساسي الخاص فيه؟ ببساطة جدا، this assay
+
+359
+00:25:21,320 --> 00:25:27,580
+is based on the labeling of 3'3-hydroxyl-M of the
+
+360
+00:25:27,580 --> 00:25:32,770
+fragmented DNA with fluorescenceDiet catalyzed by
+
+361
+00:25:32,770 --> 00:25:36,930
+terminal DTT يعني بمعنى آخر، لو أنا فيه عندي
+
+362
+00:25:36,930 --> 00:25:40,670
+الـDNA الخاص بالـSpermatozoa الموجودة في الهدف، لو
+
+363
+00:25:40,670 --> 00:25:46,410
+صار لها fragmentation، هيصير عندي Freeموجودة على
+
+364
+00:25:46,410 --> 00:25:50,770
+الـ 3 Prime الـ Free OH الموجودة على الـ 3 Prime
+
+365
+00:25:50,770 --> 00:25:57,390
+تعتبر كمكان مميز ومكان as mark indicator على وجود
+
+366
+00:25:57,390 --> 00:26:01,190
+الـ Fragmentation ففي صبغة ممكن ترتبط مع هذا
+
+367
+00:26:01,190 --> 00:26:06,870
+المكان و تعطيني fluorescent dye الـ DTTP مميز مع
+
+368
+00:26:06,870 --> 00:26:10,050
+الـ fluorescent probe نستطيع اتجاهه باستخدام
+
+369
+00:26:10,050 --> 00:26:13,910
+ميكروسكوب fluorescent أو فلو سايتوميترالوصول
+
+370
+00:26:13,910 --> 00:26:18,150
+للسيجنال الطبيعي سيكون مرتبط بقيمة الـ Strand
+
+371
+00:26:18,150 --> 00:26:23,930
+Breaks والتي ستتفكر كمية الـ sperm DNA باختصار
+
+372
+00:26:23,930 --> 00:26:28,850
+شديد الـ Tunnel هو عبارة عن تحس يستخدم لقياس مدى
+
+373
+00:26:28,850 --> 00:26:32,310
+الـ Apoptosis أو الـ DNA Fragmentation في الـ
+
+374
+00:26:32,310 --> 00:26:36,870
+spermatozoa DNA من خلال أن في مادة موجودة في هذا
+
+375
+00:26:36,870 --> 00:26:42,560
+الـ reagent لها قابلية للارتباط مع الـ OHالـ Free
+
+376
+00:26:42,560 --> 00:26:46,440
+الموجودة على الـ 3 Prime من أين أجت أن عند Double
+
+377
+00:26:46,440 --> 00:26:50,960
+Strand DNA صارها Fragmentation أدت إلى وجود Free
+
+378
+00:26:50,960 --> 00:26:55,280
+OH موجودة على الـ 3 Prime ترتبط بهذه المادة المادة
+
+379
+00:26:55,280 --> 00:27:02,000
+هذه مرتبطة بـ Fluorescent Pro إذا عرضت للـ UV أو
+
+380
+00:27:02,000 --> 00:27:06,220
+لـ Fluorescent أو لـ Fluorescent Microscope هشوفها
+
+381
+00:27:06,220 --> 00:27:10,320
+تحت الميكروسكوب فممكن أقرأها ببساطة جدا على هيئة
+
+382
+00:27:10,320 --> 00:27:15,640
+percentageفي علاقة ما بين عدد ال indicator اللتي
+
+383
+00:27:15,640 --> 00:27:19,320
+تظهر عدد ال flow اللتي تظهر عدد ال light ال
+
+384
+00:27:19,320 --> 00:27:21,920
+ignition light اللتي تظهر ال emission light اللتي
+
+385
+00:27:21,920 --> 00:27:28,860
+تظهر و نسبة ال apoptosis كل ما زاد .. كل ما زاد ال
+
+386
+00:27:28,860 --> 00:27:34,020
+signal معناه في عندي عدد كبير من ال DNA apoptosis
+
+387
+00:27:34,020 --> 00:27:38,550
+أو ال DNA fragmentationصورة بتوضح الكلمة ده هاي في
+
+388
+00:27:38,550 --> 00:27:42,550
+عندي spam double strand يعنيه صار في عندي break في
+
+389
+00:27:42,550 --> 00:27:46,310
+ال double strand أدت إلى تكوين OH3 على ال 3 prime
+
+390
+00:27:46,310 --> 00:27:52,050
+عملتلها mixing بال tunnel kit فلجيت أنه في عند ال
+
+391
+00:27:52,050 --> 00:27:57,010
+DTT انزايم ارتبط فيها ومربوط بال fluoro scan لو
+
+392
+00:27:57,010 --> 00:27:59,630
+عرضته ل flow cytometer أو fluorescent microscope
+
+393
+00:27:59,630 --> 00:28:03,150
+هتعطيني emission لونه green ال emissionأو light
+
+394
+00:28:03,150 --> 00:28:07,610
+لونه green light لونه green يتناسب تناسبان طرديا
+
+395
+00:28:07,610 --> 00:28:11,470
+مع عدد الحيوانات المنوية التي بها defect أو بها
+
+396
+00:28:11,470 --> 00:28:17,470
+apoptosis الصورة أفضل دالين هي عندي صورة ال
+
+397
+00:28:17,470 --> 00:28:24,130
+background black وفي عندي لونين لون pale green
+
+398
+00:28:24,130 --> 00:28:29,090
+فاتح أخضر فاتح و لون dark green ال dark green
+
+399
+00:28:29,090 --> 00:28:31,930
+معناه اتونال positiveماذا يعني الـ tone الـ
+
+400
+00:28:31,930 --> 00:28:35,170
+positive؟ معناه إنه في صار في عندي fragmentation
+
+401
+00:28:35,170 --> 00:28:40,070
+ارتبطت ال probe مع ال OH الـ3 الموجودة على الـ 3
+
+402
+00:28:40,070 --> 00:28:44,810
+prime معناه إذا عرضتها لفلورسانت مايكروسكوب أو
+
+403
+00:28:44,810 --> 00:28:49,570
+الفلورسكال هيعطيني signal light لونه green كل ما
+
+404
+00:28:49,570 --> 00:28:53,110
+زاد ال intensity لل green color معناه في عندي كمية
+
+405
+00:28:53,110 --> 00:28:56,610
+fragmentation أعلى أما ال pale color معناه ال tone
+
+406
+00:28:56,610 --> 00:28:59,740
+الـ negative يعني مافي عندي fragmentation هناما في
+
+407
+00:28:59,740 --> 00:29:04,200
+OH3 يرتبط فيها الـ probe هنا عشان كده بقوللي
+
+408
+00:29:04,200 --> 00:29:06,740
+Tunnel Assay for Detection of Spare DNA
+
+409
+00:29:06,740 --> 00:29:13,060
+Fragmentation Under Fluorescent Microscope الـ
+
+410
+00:29:13,060 --> 00:29:16,640
+Normal DNA هيديني الـ Light Green عشان كده بسميه
+
+411
+00:29:16,640 --> 00:29:19,920
+Tunnel Negative بينما الـ Damaged DNA أو الـ
+
+412
+00:29:19,920 --> 00:29:24,940
+Apoptosis Spare هيعطيني Bright أو Dark Green وهو
+
+413
+00:29:24,940 --> 00:29:29,740
+عبارة عن الـ Tunnel الـ Positiveعن الـ tunnel
+
+414
+00:29:29,740 --> 00:29:34,860
+positive طبعاً هذا هي عبارة عن الفكرة ما بين ال
+
+415
+00:29:34,860 --> 00:29:38,160
+tunnel positive وال tunnel ال negative الخاصة
+
+416
+00:29:38,160 --> 00:29:42,120
+بقياس ال fragmentation sperm يعني fragmentation أو
+
+417
+00:29:42,120 --> 00:29:50,660
+sperm apoptosis سنكتفي
+
+418
+00:29:50,660 --> 00:29:55,000
+بهذا القدر من المعلومات في هذه المحاضرة على أمل أن
+
+419
+00:29:55,000 --> 00:29:59,280
+نتقي في المحاضرة القادمة ان شاء اللهDom Tom في حفظ
+
+420
+00:29:59,280 --> 00:29:59,420
+الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/DYESKICx4QA_raw.json b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/DYESKICx4QA_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..5fd4f142751e30e5041edfe66ad466b22c7794d5
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/DYESKICx4QA_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 2517, "start": 0.77, "end": 25.17, "text": "بسم الله الرحمن الرحيم والصلاة والسلام على أشرف المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا العزاء أرجو من الله أن تكونوا بخير استكمالا لما بدأنا فيه من محاضرة sperm assessment processing and selection تحدثنا عن عدة أمور لها علاقة بال macroscopic examination وmicroscopic examination", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 16070, 9381, 15040, 3660, 16070, 3794, 37440, 15844, 5551, 8592, 28480, 9673, 2288, 3794, 1211, 9957, 8608, 25708, 8315, 3714, 35571, 3215, 4032, 3615, 23942, 19753, 43761, 4032, 9381, 5016, 3555, 3224, 5551, 7435, 2304, 3615, 9957, 23032, 15040, 3555, 8315, 18863, 11622, 16606, 5551, 47341, 2407, 9154, 21984, 14739, 6055, 30544, 14407, 4724, 9778, 13546, 44713, 24793, 6027, 995, 5296, 15042, 47525, 10721, 8315, 8978, 3224, 9154, 3714, 5016, 46958, 25720, 32899, 9687, 9007, 293, 9450, 6055, 24401, 12984, 8315, 18871, 6225, 41891, 5551, 2304, 13063, 5296, 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Sperm Examination من خلال فحص الأيوزين أو النجروسين استثنى استكمال لهذا الأمر، سوف نتكلم عن الـHoss Test أو ما يُعرف باسم الـHypoosmotic Swelling Test الـHypoosmotic Swelling Test، اختصار Hoss Test وهو عبارة عن فحص يُستخدم للتفريغ ما بين الحيوان المنوي الحي", "tokens": [38688, 1829, 28239, 11296, 10632, 12399, 6055, 24401, 12984, 8315, 18871, 2423, 39184, 53, 20758, 9279, 34051, 2423, 39184, 25900, 318, 610, 76, 24755, 2486, 9154, 16490, 1211, 6027, 6156, 5016, 9381, 16247, 1829, 2407, 11622, 9957, 34051, 28239, 7435, 32887, 3794, 9957, 44713, 12984, 1863, 7578, 44713, 24793, 6027, 46740, 15730, 16247, 29973, 12399, 8608, 38688, 8717, 2655, 4117, 19528, 18871, 2423, 39184, 39, 772, 9279, 34051, 19446, 7251, 10859, 3615, 28480, 4724, 32277, 2304, 2423, 39184, 38792, 2259, 329, 76, 9411, 29918, 2669, 9279, 2423, 39184, 38792, 2259, 329, 76, 9411, 29918, 2669, 9279, 12399, 1975, 46456, 9381, 9640, 389, 772, 9279, 37037, 2407, 6225, 3555, 9640, 3660, 18871, 6156, 5016, 9381, 7251, 10859, 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"probability": 0.93212890625}, {"start": 154.46, "end": 154.6, "word": " الـ", "probability": 0.673095703125}, {"start": 154.6, "end": 154.82, "word": " X", "probability": 0.1910400390625}], "temperature": 1.0}, {"id": 7, "seek": 17836, "start": 155.2, "end": 178.36, "text": "بشكل مباشر بدون أي تردد In this method, sperm sample should be mixed with the hypoosmotic solution and incubated at 37 Celsius for 30 minutes عشان انا اتأكد هذا ال sperm alive ولا لا طب اذا كانت العينة بتستخدمها للإكزي يكفي خمس دقائق تحضيرها بال hypoosmotic solution", "tokens": [3555, 8592, 28820, 3714, 3555, 33599, 2288, 47525, 11536, 36632, 6055, 2288, 3215, 3215, 682, 341, 3170, 11, 32899, 6889, 820, 312, 7467, 365, 264, 2477, 2259, 329, 76, 9411, 3827, 293, 33345, 770, 412, 13435, 22658, 337, 2217, 2077, 6225, 8592, 7649, 1975, 8315, 1975, 2655, 10721, 4117, 3215, 23758, 2423, 32899, 5465, 49429, 20193, 23032, 3555, 1975, 15730, 25961, 2655, 18863, 9957, 3660, 39894, 14851, 9778, 40448, 11296, 24976, 28814, 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0.7939453125}, {"start": 160.6, "end": 160.96, "word": " sample", "probability": 0.5673828125}, {"start": 160.96, "end": 161.2, "word": " should", "probability": 0.951171875}, {"start": 161.2, "end": 161.4, "word": " be", "probability": 0.9521484375}, {"start": 161.4, "end": 161.72, "word": " mixed", "probability": 0.90380859375}, {"start": 161.72, "end": 161.96, "word": " with", "probability": 0.92724609375}, {"start": 161.96, "end": 162.1, "word": " the", "probability": 0.7255859375}, {"start": 162.1, "end": 162.68, "word": " hypoosmotic", "probability": 0.752294921875}, {"start": 162.68, "end": 163.26, "word": " solution", "probability": 0.9541015625}, {"start": 163.26, "end": 163.96, "word": " and", "probability": 0.8974609375}, {"start": 163.96, "end": 164.72, "word": " incubated", "probability": 0.955810546875}, {"start": 164.72, "end": 165.58, "word": " at", "probability": 0.83740234375}, {"start": 165.58, "end": 166.18, "word": " 37", "probability": 0.96484375}, {"start": 166.18, "end": 166.66, "word": " Celsius", "probability": 0.252197265625}, {"start": 166.66, "end": 167.16, "word": " for", "probability": 0.9619140625}, {"start": 167.16, "end": 167.8, "word": " 30", "probability": 0.9462890625}, {"start": 167.8, "end": 168.2, "word": " minutes", "probability": 0.7998046875}, {"start": 168.2, "end": 168.76, "word": " عشان", "probability": 0.9571940104166666}, {"start": 168.76, "end": 169.04, "word": " انا", "probability": 0.66845703125}, {"start": 169.04, "end": 169.78, "word": " اتأكد", "probability": 0.8953125}, {"start": 169.78, "end": 169.96, "word": " هذا", "probability": 0.387451171875}, {"start": 169.96, "end": 170.1, "word": " ال", "probability": 0.94921875}, {"start": 170.1, "end": 170.34, "word": " sperm", "probability": 0.92333984375}, {"start": 170.34, "end": 170.7, "word": " alive", "probability": 0.40576171875}, {"start": 170.7, "end": 170.96, "word": " ولا", "probability": 0.73583984375}, {"start": 170.96, "end": 171.42, "word": " لا", "probability": 0.69970703125}, {"start": 171.42, "end": 171.86, "word": " طب", "probability": 0.6885986328125}, {"start": 171.86, "end": 172.0, "word": " اذا", "probability": 0.80322265625}, {"start": 172.0, "end": 172.26, "word": " كانت", "probability": 0.8935546875}, {"start": 172.26, "end": 172.56, "word": " العينة", "probability": 0.81884765625}, {"start": 172.56, "end": 173.12, "word": " بتستخدمها", "probability": 0.96123046875}, {"start": 173.12, "end": 173.7, "word": " للإكزي", "probability": 0.66875}, {"start": 173.7, "end": 174.32, "word": " يكفي", "probability": 0.8409830729166666}, {"start": 174.32, "end": 174.72, "word": " خمس", "probability": 0.8169759114583334}, {"start": 174.72, "end": 175.2, "word": " دقائق", "probability": 0.9461669921875}, {"start": 175.2, "end": 175.92, "word": " تحضيرها", "probability": 0.94990234375}, {"start": 175.92, "end": 176.34, "word": " بال", "probability": 0.93701171875}, {"start": 176.34, "end": 177.6, "word": " hypoosmotic", "probability": 0.80087890625}, {"start": 177.6, "end": 178.36, "word": " solution", "probability": 0.966796875}], "temperature": 1.0}, {"id": 8, "seek": 20735, "start": 179.57, "end": 207.35, "text": "بعد عملية أحضين على 37 درجة مئوية لمدة 30 دقيقة أو لمدة 5 دقائق باجي بعمل check up لل sperm أو بعد ال sperm بعمل with preparation على ال slide should be made and assess the sample under phase contrast microscope على عدسة تكبير 400 أو 200 بعيد 200 sperm بشوف مين فيهم life و مين فيهم dead", "tokens": [3555, 22488, 6225, 42213, 10632, 5551, 5016, 11242, 9957, 15844, 13435, 11778, 47341, 3660, 3714, 19986, 2407, 10632, 32767, 41891, 2217, 11778, 38436, 28671, 34051, 32767, 41891, 1025, 11778, 4587, 16373, 4587, 4724, 26108, 1829, 4724, 25957, 1211, 1520, 493, 24976, 32899, 34051, 45030, 3215, 2423, 32899, 4724, 25957, 1211, 365, 13081, 15844, 2423, 4137, 820, 312, 1027, 293, 5877, 264, 6889, 833, 5574, 8712, 29753, 15844, 6225, 3215, 3794, 3660, 6055, 4117, 3555, 13546, 8423, 34051, 2331, 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بعد", "probability": 0.564697265625}, {"start": 190.71, "end": 191.15, "word": " ال", "probability": 0.76611328125}, {"start": 191.15, "end": 191.53, "word": " sperm", "probability": 0.94091796875}, {"start": 191.53, "end": 193.27, "word": " بعمل", "probability": 0.9669596354166666}, {"start": 193.27, "end": 193.49, "word": " with", "probability": 0.1885986328125}, {"start": 193.49, "end": 194.61, "word": " preparation", "probability": 0.92236328125}, {"start": 194.61, "end": 195.09, "word": " على", "probability": 0.7978515625}, {"start": 195.09, "end": 195.23, "word": " ال", "probability": 0.9111328125}, {"start": 195.23, "end": 195.57, "word": " slide", "probability": 0.9267578125}, {"start": 195.57, "end": 195.87, "word": " should", "probability": 0.7265625}, {"start": 195.87, "end": 196.07, "word": " be", "probability": 0.9599609375}, {"start": 196.07, "end": 196.41, "word": " made", "probability": 0.7998046875}, {"start": 196.41, "end": 197.21, "word": " and", "probability": 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{"start": 202.01, "end": 202.37, "word": " 200", "probability": 0.92724609375}, {"start": 202.37, "end": 203.27, "word": " بعيد", "probability": 0.603759765625}, {"start": 203.27, "end": 203.63, "word": " 200", "probability": 0.92578125}, {"start": 203.63, "end": 204.53, "word": " sperm", "probability": 0.90283203125}, {"start": 204.53, "end": 205.29, "word": " بشوف", "probability": 0.9205729166666666}, {"start": 205.29, "end": 205.53, "word": " مين", "probability": 0.940185546875}, {"start": 205.53, "end": 205.97, "word": " فيهم", "probability": 0.98095703125}, {"start": 205.97, "end": 206.45, "word": " life", "probability": 0.52685546875}, {"start": 206.45, "end": 206.61, "word": " و", "probability": 0.98388671875}, {"start": 206.61, "end": 206.79, "word": " مين", "probability": 0.755615234375}, {"start": 206.79, "end": 207.05, "word": " فيهم", "probability": 0.986328125}, {"start": 207.05, "end": 207.35, "word": " dead", "probability": 0.7412109375}], "temperature": 1.0}, {"id": 9, "seek": 23533, "start": 207.61, "end": 235.33, "text": "بناء على الانتفاخ اللي يظهر أسفل الذئب في هذا الشكل طبعا دي اللي على اليسار رقم A هي عبارة عن ال fertility test بفعل النجروسين أو ال Iosin بضيف I قطرة من ال Iosin بضيف قطرة من النجروسين و بضيف قطرة من السيمن بعمله mix او واحد سيمن اتنين drop Iosin اتنين drop نجروسين بعمل mix و بشوفها تحت الميكروسكوب اللي بالشب هو ال life", "tokens": [3555, 1863, 16606, 15844, 2423, 7649, 2655, 5172, 47283, 13672, 1829, 7251, 19913, 3224, 2288, 5551, 3794, 5172, 1211, 32545, 19986, 3555, 8978, 23758, 25124, 28820, 23032, 3555, 3615, 995, 11778, 1829, 13672, 1829, 15844, 45595, 3794, 9640, 12602, 4587, 2304, 316, 39896, 6225, 3555, 9640, 3660, 18871, 2423, 31707, 1500, 4724, 5172, 30241, 28239, 7435, 32887, 3794, 9957, 34051, 2423, 286, 329, 259, 4724, 11242, 33911, 286, 12174, 9566, 25720, 9154, 2423, 286, 329, 259, 4724, 11242, 33911, 12174, 9566, 25720, 9154, 28239, 7435, 32887, 3794, 9957, 4032, 4724, 11242, 33911, 12174, 9566, 25720, 9154, 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{"start": 226.17, "end": 226.61, "word": " بعمله", "probability": 0.8084309895833334}, {"start": 226.61, "end": 226.95, "word": " mix", "probability": 0.857421875}, {"start": 226.95, "end": 227.27, "word": " او", "probability": 0.7454833984375}, {"start": 227.27, "end": 227.69, "word": " واحد", "probability": 0.7010498046875}, {"start": 227.69, "end": 228.13, "word": " سيمن", "probability": 0.7731119791666666}, {"start": 228.13, "end": 228.53, "word": " اتنين", "probability": 0.9105224609375}, {"start": 228.53, "end": 228.97, "word": " drop", "probability": 0.415771484375}, {"start": 228.97, "end": 229.93, "word": " Iosin", "probability": 0.9407552083333334}, {"start": 229.93, "end": 230.19, "word": " اتنين", "probability": 0.9788818359375}, {"start": 230.19, "end": 230.45, "word": " drop", "probability": 0.97119140625}, {"start": 230.45, "end": 231.07, "word": " نجروسين", "probability": 0.97001953125}, {"start": 231.07, "end": 231.69, "word": " بعمل", "probability": 0.81689453125}, {"start": 231.69, "end": 231.99, "word": " mix", "probability": 0.95703125}, {"start": 231.99, "end": 232.19, "word": " و", "probability": 0.7158203125}, {"start": 232.19, "end": 232.51, "word": " بشوفها", "probability": 0.967529296875}, {"start": 232.51, "end": 232.75, "word": " تحت", "probability": 0.994873046875}, {"start": 232.75, "end": 233.49, "word": " الميكروسكوب", "probability": 0.7217843191964286}, {"start": 233.49, "end": 234.17, "word": " اللي", "probability": 0.81884765625}, {"start": 234.17, "end": 234.73, "word": " بالشب", "probability": 0.5506184895833334}, {"start": 234.73, "end": 234.93, "word": " هو", "probability": 0.8837890625}, {"start": 234.93, "end": 235.09, "word": " ال", "probability": 0.77978515625}, {"start": 235.09, "end": 235.33, "word": " life", "probability": 0.8759765625}], "temperature": 1.0}, {"id": 10, "seek": 26245, "start": 236.5, "end": 262.46, "text": "أما الأخر صفقة الـ Iosin هو الـ dead أو الـ non-viable اللي على اليسار هي عبارة عن الـ hypo osmotic swelling test الـ host test بضيف sample من الـ seminal fluid بضيف عليه الـ hypo osmotic swelling fluid or solution وبعمل mixing وincubation لمدة 30 أو 5 دقائق", "tokens": [10721, 15042, 16247, 34740, 20328, 5172, 28671, 2423, 39184, 286, 329, 259, 31439, 2423, 39184, 3116, 34051, 2423, 39184, 2107, 12, 4917, 712, 13672, 1829, 15844, 45595, 3794, 9640, 39896, 6225, 3555, 9640, 3660, 18871, 2423, 39184, 2477, 2259, 3003, 76, 9411, 33127, 1500, 2423, 39184, 3975, 1500, 4724, 11242, 33911, 6889, 9154, 2423, 39184, 4361, 2071, 9113, 4724, 11242, 33911, 47356, 2423, 39184, 2477, 2259, 3003, 76, 9411, 33127, 9113, 420, 3827, 46599, 25957, 1211, 11983, 4032, 4647, 836, 399, 32767, 41891, 2217, 34051, 1025, 11778, 4587, 16373, 4587], "avg_logprob": -0.2695741790991563, "compression_ratio": 1.5605381165919283, "no_speech_prob": 1.1920928955078125e-07, "words": [{"start": 236.5, "end": 236.96, "word": "أما", "probability": 0.929931640625}, {"start": 236.96, "end": 237.5, "word": " الأخر", 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{"start": 248.66, "end": 249.7, "word": " بضيف", "probability": 0.8473307291666666}, {"start": 249.7, "end": 251.42, "word": " sample", "probability": 0.6904296875}, {"start": 251.42, "end": 252.14, "word": " من", "probability": 0.99169921875}, {"start": 252.14, "end": 252.36, "word": " الـ", "probability": 0.42535400390625}, {"start": 252.36, "end": 252.64, "word": " seminal", "probability": 0.7149658203125}, {"start": 252.64, "end": 253.04, "word": " fluid", "probability": 0.9091796875}, {"start": 253.04, "end": 253.5, "word": " بضيف", "probability": 0.90625}, {"start": 253.5, "end": 253.7, "word": " عليه", "probability": 0.958984375}, {"start": 253.7, "end": 253.86, "word": " الـ", "probability": 0.745361328125}, {"start": 253.86, "end": 254.14, "word": " hypo", "probability": 0.9462890625}, {"start": 254.14, "end": 254.68, "word": " osmotic", "probability": 0.9466145833333334}, {"start": 254.68, "end": 255.28, "word": " swelling", "probability": 0.90478515625}, {"start": 255.28, "end": 255.9, "word": " fluid", "probability": 0.9189453125}, {"start": 255.9, "end": 256.54, "word": " or", "probability": 0.38623046875}, {"start": 256.54, "end": 257.08, "word": " solution", "probability": 0.95263671875}, {"start": 257.08, "end": 257.68, "word": " وبعمل", "probability": 0.83251953125}, {"start": 257.68, "end": 258.18, "word": " mixing", "probability": 0.86767578125}, {"start": 258.18, "end": 259.36, "word": " وincubation", "probability": 0.87548828125}, {"start": 259.36, "end": 260.18, "word": " لمدة", "probability": 0.918701171875}, {"start": 260.18, "end": 261.3, "word": " 30", "probability": 0.5849609375}, {"start": 261.3, "end": 261.58, "word": " أو", "probability": 0.90380859375}, {"start": 261.58, "end": 261.86, "word": " 5", "probability": 0.91455078125}, {"start": 261.86, "end": 262.46, "word": " دقائق", "probability": 0.9761962890625}], "temperature": 1.0}, {"id": 11, "seek": 28636, "start": 262.62, "end": 286.36, "text": "على 37 درجة مهوية أي sperm بظهر لـ swelling في أسفله هذا معناه normal sperm swelling زي ما أحنا شايفينه على جهة اليسار في منطقة التل بسميه normal sperm viable sperm أما إذا كان مافيه swelling في نهاية التل فهو عبارة عن non viable sperm أو dead sperm هذا الفرق ما بين الفرقتان", "tokens": [3615, 23942, 13435, 11778, 47341, 3660, 3714, 3224, 2407, 10632, 36632, 32899, 4724, 19913, 3224, 2288, 5296, 39184, 33127, 8978, 5551, 3794, 5172, 43761, 23758, 20449, 8315, 3224, 2710, 32899, 33127, 30767, 1829, 19446, 5551, 5016, 8315, 13412, 995, 33911, 9957, 3224, 15844, 10874, 3224, 3660, 45595, 3794, 9640, 8978, 9154, 9566, 28671, 16712, 1211, 4724, 38251, 1829, 3224, 2710, 32899, 22024, 32899, 5551, 15042, 11933, 15730, 25961, 19446, 41185, 3224, 33127, 8978, 8717, 11296, 10632, 16712, 1211, 6156, 3224, 2407, 6225, 3555, 9640, 3660, 18871, 2107, 22024, 32899, 34051, 3116, 32899, 23758, 27188, 2288, 4587, 19446, 49374, 27188, 2288, 4587, 2655, 7649], "avg_logprob": -0.16721754793364269, "compression_ratio": 1.771551724137931, 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277.98, "end": 278.18, "word": " في", "probability": 0.958984375}, {"start": 278.18, "end": 278.4, "word": " نهاية", "probability": 0.8702799479166666}, {"start": 278.4, "end": 278.74, "word": " التل", "probability": 0.96533203125}, {"start": 278.74, "end": 279.0, "word": " فهو", "probability": 0.9708658854166666}, {"start": 279.0, "end": 279.44, "word": " عبارة", "probability": 0.9969482421875}, {"start": 279.44, "end": 279.8, "word": " عن", "probability": 0.99755859375}, {"start": 279.8, "end": 280.7, "word": " non", "probability": 0.86181640625}, {"start": 280.7, "end": 281.66, "word": " viable", "probability": 0.5322265625}, {"start": 281.66, "end": 282.42, "word": " sperm", "probability": 0.9716796875}, {"start": 282.42, "end": 283.14, "word": " أو", "probability": 0.8291015625}, {"start": 283.14, "end": 283.6, "word": " dead", "probability": 0.919921875}, {"start": 283.6, "end": 284.16, "word": " sperm", "probability": 0.97802734375}, {"start": 284.16, "end": 284.58, "word": " هذا", "probability": 0.60693359375}, {"start": 284.58, "end": 284.98, "word": " الفرق", "probability": 0.9703776041666666}, {"start": 284.98, "end": 285.14, "word": " ما", "probability": 0.4609375}, {"start": 285.14, "end": 285.42, "word": " بين", "probability": 0.9150390625}, {"start": 285.42, "end": 286.36, "word": " الفرقتان", "probability": 0.690673828125}], "temperature": 1.0}, {"id": 12, "seek": 31636, "start": 286.94, "end": 316.36, "text": "في طريقة تانية وهي طريقة العدو معتمدة على الكمبيوتر بنسميها Computerized Assisted Sperm Analysis أو Computer Assisted Sperm Analysis تحت مصطلح كذا كذا C للكمبيوتر A Assisted Sperm Analysis يعني أنت كتكنيشن ما بتشتغل شيء إلا بتعمل weight mount يعني كتانك تضيف خمسين micro من", "tokens": [41185, 23032, 16572, 28671, 6055, 7649, 10632, 37037, 1829, 23032, 16572, 28671, 18863, 3215, 2407, 3714, 34268, 2304, 41891, 15844, 2423, 24793, 21292, 35473, 2288, 4724, 1863, 38251, 1829, 11296, 22289, 1602, 6281, 33250, 318, 610, 76, 38172, 34051, 22289, 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288.72, "end": 289.36, "word": " العدو", "probability": 0.6982421875}, {"start": 289.36, "end": 290.0, "word": " معتمدة", "probability": 0.813232421875}, {"start": 290.0, "end": 290.22, "word": " على", "probability": 0.86962890625}, {"start": 290.22, "end": 290.9, "word": " الكمبيوتر", "probability": 0.9759765625}, {"start": 290.9, "end": 291.42, "word": " بنسميها", "probability": 0.788330078125}, {"start": 291.42, "end": 294.48, "word": " Computerized", "probability": 0.437744140625}, {"start": 294.48, "end": 295.6, "word": " Assisted", "probability": 0.5484619140625}, {"start": 295.6, "end": 296.38, "word": " Sperm", "probability": 0.8942057291666666}, {"start": 296.38, "end": 297.24, "word": " Analysis", "probability": 0.95166015625}, {"start": 297.24, "end": 297.9, "word": " أو", "probability": 0.73681640625}, {"start": 297.9, "end": 298.96, "word": " Computer", "probability": 0.88623046875}, {"start": 298.96, "end": 299.9, "word": " Assisted", "probability": 0.9560546875}, {"start": 299.9, "end": 300.56, "word": " Sperm", "probability": 0.9708658854166666}, {"start": 300.56, "end": 301.08, "word": " Analysis", "probability": 0.97900390625}, {"start": 301.08, "end": 301.92, "word": " تحت", "probability": 0.975830078125}, {"start": 301.92, "end": 302.46, "word": " مصطلح", "probability": 0.97529296875}, {"start": 302.46, "end": 303.18, "word": " كذا", "probability": 0.62353515625}, {"start": 303.18, "end": 304.16, "word": " كذا", "probability": 0.795166015625}, {"start": 304.16, "end": 304.84, "word": " C", "probability": 0.18212890625}, {"start": 304.84, "end": 306.1, "word": " للكمبيوتر", "probability": 0.888916015625}, {"start": 306.1, "end": 306.66, "word": " A", "probability": 0.783203125}, {"start": 306.66, "end": 307.84, "word": " Assisted", "probability": 0.791015625}, {"start": 307.84, "end": 308.92, "word": " Sperm", "probability": 0.9479166666666666}, {"start": 308.92, "end": 310.44, "word": " Analysis", "probability": 0.58935546875}, {"start": 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880.37, "text": "إذا لم تحدث هذه العملية، معناه إن الـDNA الموجود داخل الـSperm هيكون أكثر حساسية للتلف والتكسير طيب، شو اللي هيكسر؟ وشو هيخليه عرض للتلف؟ بقول الـDNA الـdamage can occur only during spermatogenesis أكيد، but also during storage in epidermis or transport from one place to another يعني معنى آخر إن الـSperm طالما خُلق", "tokens": [28814, 15730, 32767, 6055, 24401, 12984, 29538, 18863, 42213, 10632, 12399, 20449, 8315, 3224, 36145, 2423, 39184, 35, 5321, 9673, 29245, 23328, 11778, 47283, 1211, 2423, 39184, 50, 610, 76, 39896, 30544, 5551, 4117, 49115, 11331, 3794, 32277, 10632, 24976, 2655, 46538, 16070, 2655, 4117, 3794, 13546, 23032, 1829, 3555, 12399, 13412, 2407, 13672, 1829, 39896, 4117, 3794, 2288, 22807, 4032, 8592, 2407, 39896, 9778, 20292, 3224, 6225, 43042, 24976, 2655, 46538, 22807, 4724, 39648, 2423, 39184, 35, 5321, 2423, 39184, 10170, 609, 393, 5160, 787, 1830, 24152, 15677, 8799, 9374, 5551, 4117, 25708, 12399, 457, 611, 1830, 6725, 294, 2388, 327, 966, 271, 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"word": " أكيد،", "probability": 0.8846435546875}, {"start": 870.83, "end": 871.09, "word": " but", "probability": 0.9140625}, {"start": 871.09, "end": 871.69, "word": " also", "probability": 0.8388671875}, {"start": 871.69, "end": 872.43, "word": " during", "probability": 0.8779296875}, {"start": 872.43, "end": 872.91, "word": " storage", "probability": 0.9189453125}, {"start": 872.91, "end": 873.13, "word": " in", "probability": 0.86669921875}, {"start": 873.13, "end": 873.81, "word": " epidermis", "probability": 0.7250213623046875}, {"start": 873.81, "end": 874.45, "word": " or", "probability": 0.44189453125}, {"start": 874.45, "end": 875.25, "word": " transport", "probability": 0.7275390625}, {"start": 875.25, "end": 875.61, "word": " from", "probability": 0.90185546875}, {"start": 875.61, "end": 875.81, "word": " one", "probability": 0.939453125}, {"start": 875.81, "end": 876.19, "word": " place", "probability": 0.90966796875}, {"start": 876.19, "end": 876.33, "word": " to", 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transfer من منطقة إلى منطقة يودي إلى تلفد يعني", "tokens": [12610, 2304, 7251, 24401, 12984, 46740, 18871, 36632, 37893, 28820, 3660, 16490, 1211, 6027, 6225, 42213, 16712, 9778, 20292, 4587, 14739, 3224, 4724, 1829, 30544, 8978, 3224, 5551, 2304, 7649, 4032, 41185, 3224, 3714, 41361, 3714, 10721, 2304, 11536, 18871, 9673, 9778, 41193, 2288, 5296, 10721, 3714, 43020, 7251, 2655, 3615, 43042, 30731, 8320, 5952, 34051, 1071, 5952, 16490, 1211, 6027, 6225, 42213, 10632, 16712, 9778, 11622, 9957, 8978, 2423, 595, 327, 966, 271, 34051, 16490, 1211, 6027, 6225, 42213, 10632, 2423, 10012, 326, 2776, 34051, 16490, 1211, 6027, 2423, 5003, 9154, 9154, 9566, 28671, 30731, 9154, 9566, 28671, 7251, 23328, 1829, 30731, 6055, 46538, 3215, 37495, 22653], "avg_logprob": -0.17416857798165136, "compression_ratio": 1.7659574468085106, "no_speech_prob": 1.4901161193847656e-06, "words": [{"start": 880.87, "end": 881.25, "word": "ولم", "probability": 0.8583984375}, {"start": 881.25, "end": 881.65, "word": " 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901.78, "end": 918.72, "text": "من أشهر العوامل التي تؤدي إلى DNA damage هي عبارة عن Oxidative Stress اللي بتسميه OS شو يعني Oxidative Stress؟ ببساطة في أجسامنا في حاجة اسمها Free Radical وفي حاجة اسمها Antioxidant لازم يصير فيه balance ما بين ال antioxidant", "tokens": [27842, 5551, 8592, 3224, 2288, 18863, 2407, 10943, 1211, 38392, 6055, 33604, 16254, 30731, 8272, 4344, 39896, 6225, 3555, 9640, 3660, 18871, 16489, 327, 1166, 38258, 13672, 1829, 39894, 38251, 1829, 3224, 12731, 13412, 2407, 37495, 22653, 16489, 327, 1166, 38258, 22807, 4724, 3555, 3794, 41193, 3660, 8978, 5551, 7435, 3794, 10943, 8315, 8978, 11331, 26108, 3660, 24525, 2304, 11296, 11551, 9654, 804, 4032, 41185, 11331, 26108, 3660, 24525, 2304, 11296, 5130, 30565, 394, 5296, 31377, 2304, 7251, 9381, 13546, 8978, 3224, 4772, 19446, 49374, 2423, 33369, 394], "avg_logprob": -0.15862007757251181, "compression_ratio": 1.4954954954954955, "no_speech_prob": 4.76837158203125e-07, "words": [{"start": 901.78, "end": 902.02, 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{"start": 1704.13, "end": 1704.85, "word": " فاتح", "probability": 0.9542643229166666}, {"start": 1704.85, "end": 1705.21, "word": " أخضر", "probability": 0.82958984375}, {"start": 1705.21, "end": 1705.85, "word": " فاتح", "probability": 0.99267578125}, {"start": 1705.85, "end": 1706.17, "word": " و", "probability": 0.76904296875}, {"start": 1706.17, "end": 1706.51, "word": " لون", "probability": 0.834228515625}, {"start": 1706.51, "end": 1707.33, "word": " dark", "probability": 0.951171875}, {"start": 1707.33, "end": 1707.71, "word": " green", "probability": 0.92919921875}, {"start": 1707.71, "end": 1708.39, "word": " ال", "probability": 0.92919921875}, {"start": 1708.39, "end": 1708.65, "word": " dark", "probability": 0.95751953125}, {"start": 1708.65, "end": 1709.09, "word": " green", "probability": 0.94482421875}, {"start": 1709.09, "end": 1709.69, "word": " معناه", "probability": 0.9700520833333334}, {"start": 1709.69, "end": 1710.23, "word": " اتونال", "probability": 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ال", "probability": 0.94580078125}, {"start": 1735.35, "end": 1735.51, "word": " pale", "probability": 0.69873046875}, {"start": 1735.51, "end": 1735.91, "word": " color", "probability": 0.90771484375}, {"start": 1735.91, "end": 1736.29, "word": " معناه", "probability": 0.9410807291666666}, {"start": 1736.29, "end": 1736.41, "word": " ال", "probability": 0.67333984375}, {"start": 1736.41, "end": 1736.61, "word": " tone", "probability": 0.89208984375}, {"start": 1736.61, "end": 1736.83, "word": " الـ", "probability": 0.5765380859375}, {"start": 1736.83, "end": 1737.15, "word": " negative", "probability": 0.92529296875}, {"start": 1737.15, "end": 1737.51, "word": " يعني", "probability": 0.957763671875}, {"start": 1737.51, "end": 1737.81, "word": " مافي", "probability": 0.8916015625}, {"start": 1737.81, "end": 1738.05, "word": " عندي", "probability": 0.906982421875}, {"start": 1738.05, "end": 1738.63, "word": " fragmentation", "probability": 0.893310546875}, {"start": 1738.63, "end": 1738.91, "word": " هنا", "probability": 0.99609375}], "temperature": 1.0}, {"id": 68, "seek": 176764, "start": 1739.3, "end": 1767.64, "text": "ما في OH3 يرتبط فيها الـ probe هنا عشان كده بقوللي Tunnel Assay for Detection of Spare DNA Fragmentation Under Fluorescent Microscope الـ Normal DNA هيديني الـ Light Green عشان كده بسميه Tunnel Negative بينما الـ Damaged DNA أو الـ Apoptosis Spare هيعطيني Bright أو Dark Green وهو عبارة عن الـ Tunnel الـ Positive", "tokens": [15042, 8978, 13931, 18, 7251, 43500, 3555, 9566, 8978, 11296, 2423, 39184, 22715, 34105, 6225, 8592, 7649, 9122, 3215, 3224, 4724, 39648, 20292, 21363, 6396, 6281, 320, 337, 4237, 10183, 295, 1738, 543, 8272, 479, 3731, 19631, 6974, 33612, 2706, 2207, 5818, 2635, 13960, 2423, 39184, 21277, 8272, 39896, 3215, 9957, 1829, 2423, 39184, 8279, 6969, 6225, 8592, 7649, 9122, 3215, 3224, 4724, 38251, 1829, 3224, 21363, 6396, 43230, 49374, 15042, 2423, 39184, 5885, 2980, 8272, 34051, 2423, 39184, 8723, 5747, 8211, 1738, 543, 39896, 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Tunnel", "probability": 0.920166015625}, {"start": 1756.98, "end": 1757.52, "word": " Negative", "probability": 0.60986328125}, {"start": 1757.52, "end": 1758.38, "word": " بينما", "probability": 0.9697265625}, {"start": 1758.38, "end": 1758.72, "word": " الـ", "probability": 0.79541015625}, {"start": 1758.72, "end": 1758.98, "word": " Damaged", "probability": 0.880615234375}, {"start": 1758.98, "end": 1759.44, "word": " DNA", "probability": 0.96826171875}, {"start": 1759.44, "end": 1759.8, "word": " أو", "probability": 0.77783203125}, {"start": 1759.8, "end": 1759.92, "word": " الـ", "probability": 0.689697265625}, {"start": 1759.92, "end": 1760.44, "word": " Apoptosis", "probability": 0.8336588541666666}, {"start": 1760.44, "end": 1760.88, "word": " Spare", "probability": 0.719482421875}, {"start": 1760.88, "end": 1761.92, "word": " هيعطيني", "probability": 0.8140625}, {"start": 1761.92, "end": 1762.7, "word": " Bright", "probability": 0.2469482421875}, {"start": 1762.7, "end": 1763.04, "word": " أو", "probability": 0.388671875}, {"start": 1763.04, "end": 1763.5, "word": " Dark", "probability": 0.884765625}, {"start": 1763.5, "end": 1764.28, "word": " Green", "probability": 0.951171875}, {"start": 1764.28, "end": 1764.94, "word": " وهو", "probability": 0.854248046875}, {"start": 1764.94, "end": 1765.52, "word": " عبارة", "probability": 0.995361328125}, {"start": 1765.52, "end": 1765.78, "word": " عن", "probability": 0.99755859375}, {"start": 1765.78, "end": 1766.06, "word": " الـ", "probability": 0.6102294921875}, {"start": 1766.06, "end": 1766.52, "word": " Tunnel", "probability": 0.94921875}, {"start": 1766.52, "end": 1767.3, "word": " الـ", "probability": 0.571044921875}, {"start": 1767.3, "end": 1767.64, "word": " Positive", "probability": 0.8505859375}], "temperature": 1.0}, {"id": 69, "seek": 179750, "start": 1769.06, "end": 1797.5, "text": "عن الـ tunnel positive طبعاً هذا هي عبارة عن الفكرة ما بين ال tunnel positive وال tunnel ال negative الخاصة بقياس ال fragmentation sperm يعني fragmentation أو sperm apoptosis سنكتفي بهذا القدر من المعلومات في هذه المحاضرة على أمل أن نتقي في المحاضرة القادمة ان شاء الله", "tokens": [3615, 1863, 2423, 39184, 13186, 3353, 23032, 3555, 3615, 995, 14111, 23758, 39896, 6225, 3555, 9640, 3660, 18871, 27188, 4117, 25720, 19446, 49374, 2423, 13186, 3353, 16070, 13186, 2423, 3671, 33962, 33546, 3660, 4724, 4587, 25528, 3794, 2423, 9241, 19631, 32899, 37495, 22653, 9241, 19631, 34051, 32899, 1882, 5747, 8211, 8608, 1863, 4117, 2655, 41185, 39627, 15730, 25062, 3215, 2288, 9154, 9673, 30241, 20498, 9307, 8978, 29538, 9673, 5016, 46958, 25720, 15844, 5551, 42213, 14739, 8717, 2655, 38436, 8978, 9673, 5016, 46958, 25720, 25062, 18513, 46007, 16472, 13412, 16606, 21984], "avg_logprob": -0.18973214121965262, "compression_ratio": 1.7841409691629957, "no_speech_prob": 4.708766937255859e-06, "words": [{"start": 1769.06, "end": 1769.38, "word": "عن", "probability": 0.836181640625}, {"start": 1769.38, "end": 1769.56, "word": " الـ", "probability": 0.806396484375}, {"start": 1769.56, "end": 1769.74, "word": " tunnel", "probability": 0.40087890625}, {"start": 1769.74, "end": 1770.22, "word": " positive", "probability": 0.83349609375}, {"start": 1770.22, "end": 1770.84, "word": " طبعاً", "probability": 0.86171875}, {"start": 1770.84, "end": 1771.1, "word": " هذا", "probability": 0.4267578125}, {"start": 1771.1, "end": 1771.68, "word": " هي", "probability": 0.346435546875}, {"start": 1771.68, "end": 1772.36, "word": " عبارة", "probability": 0.995849609375}, {"start": 1772.36, "end": 1773.02, "word": " عن", "probability": 0.984375}, {"start": 1773.02, "end": 1773.94, "word": " الفكرة", "probability": 0.9685872395833334}, {"start": 1773.94, "end": 1774.28, "word": " ما", "probability": 0.728515625}, {"start": 1774.28, "end": 1774.56, "word": " بين", "probability": 0.994140625}, {"start": 1774.56, "end": 1774.86, "word": " ال", "probability": 0.92724609375}, {"start": 1774.86, "end": 1775.06, "word": " tunnel", "probability": 0.7646484375}, {"start": 1775.06, "end": 1775.52, "word": " positive", "probability": 0.888671875}, {"start": 1775.52, "end": 1776.0, "word": " وال", "probability": 0.479248046875}, {"start": 1776.0, "end": 1776.36, "word": " tunnel", "probability": 0.91650390625}, {"start": 1776.36, "end": 1776.68, "word": " ال", "probability": 0.634765625}, {"start": 1776.68, "end": 1777.08, "word": " negative", "probability": 0.7353515625}, {"start": 1777.08, "end": 1778.16, "word": " الخاصة", "probability": 0.9583333333333334}, {"start": 1778.16, "end": 1778.76, "word": " بقياس", "probability": 0.9407958984375}, {"start": 1778.76, "end": 1778.9, "word": " ال", "probability": 0.2978515625}, {"start": 1778.9, "end": 1779.72, "word": " fragmentation", "probability": 0.852294921875}, {"start": 1779.72, "end": 1780.44, "word": " sperm", "probability": 0.481689453125}, {"start": 1780.44, "end": 1780.74, "word": " يعني", "probability": 0.6002197265625}, {"start": 1780.74, "end": 1781.48, "word": " fragmentation", "probability": 0.778076171875}, {"start": 1781.48, "end": 1782.12, "word": " أو", "probability": 0.3408203125}, {"start": 1782.12, "end": 1782.74, "word": " sperm", "probability": 0.955078125}, {"start": 1782.74, "end": 1783.9, "word": " apoptosis", "probability": 0.8738606770833334}, {"start": 1783.9, "end": 1790.66, "word": " سنكتفي", "probability": 0.95625}, {"start": 1790.66, "end": 1791.04, "word": " بهذا", "probability": 0.964599609375}, {"start": 1791.04, "end": 1791.54, "word": " القدر", "probability": 0.9944661458333334}, {"start": 1791.54, "end": 1792.04, "word": " من", "probability": 0.98291015625}, {"start": 1792.04, "end": 1793.04, "word": " المعلومات", "probability": 0.990966796875}, {"start": 1793.04, "end": 1793.16, "word": " في", "probability": 0.9736328125}, {"start": 1793.16, "end": 1793.34, "word": " هذه", "probability": 0.460205078125}, {"start": 1793.34, "end": 1793.92, "word": " المحاضرة", "probability": 0.9779052734375}, {"start": 1793.92, "end": 1794.32, "word": " على", "probability": 0.9111328125}, {"start": 1794.32, "end": 1794.68, "word": " أمل", "probability": 0.90234375}, {"start": 1794.68, "end": 1795.0, "word": " أن", "probability": 0.82177734375}, {"start": 1795.0, "end": 1795.38, "word": " نتقي", "probability": 0.6788736979166666}, {"start": 1795.38, "end": 1795.56, "word": " في", "probability": 0.9697265625}, {"start": 1795.56, "end": 1796.08, "word": " المحاضرة", "probability": 0.9927978515625}, {"start": 1796.08, "end": 1796.7, "word": " القادمة", "probability": 0.9939778645833334}, {"start": 1796.7, "end": 1797.12, "word": " ان", "probability": 0.5009765625}, {"start": 1797.12, "end": 1797.38, "word": " شاء", "probability": 0.959228515625}, {"start": 1797.38, "end": 1797.5, "word": " الله", "probability": 0.9228515625}], "temperature": 1.0}, {"id": 70, "seek": 179942, "start": 1797.98, "end": 1799.42, "text": "Dom Tom في حفظ الله", "tokens": [35, 298, 5041, 8978, 11331, 5172, 19913, 21984], "avg_logprob": -0.3155381944444444, "compression_ratio": 0.8235294117647058, "no_speech_prob": 0.0, "words": [{"start": 1797.98, "end": 1798.3, "word": "Dom", "probability": 0.52197265625}, {"start": 1798.3, "end": 1798.56, "word": " Tom", "probability": 0.70849609375}, {"start": 1798.56, "end": 1798.9, "word": " في", "probability": 0.9208984375}, {"start": 1798.9, "end": 1799.28, "word": " حفظ", "probability": 0.789306640625}, {"start": 1799.28, "end": 1799.42, "word": " الله", "probability": 0.87939453125}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1836.9770625, "duration_after_vad": 1758.4231249999964}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/DYESKICx4QA_raw.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/DYESKICx4QA_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..939afd60d0f7c06206748c7b12ff8bd0b1f085bf
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/DYESKICx4QA_raw.srt
@@ -0,0 +1,1716 @@
+1
+00:00:00,770 --> 00:00:04,450
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:04,450 --> 00:00:09,830
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا
+
+3
+00:00:09,830 --> 00:00:14,270
+العزاء أرجو من الله أن تكونوا بخير استكمالا لما
+
+4
+00:00:14,270 --> 00:00:17,930
+بدأنا فيه من محاضرة sperm assessment processing
+
+5
+00:00:17,930 --> 00:00:22,230
+and selection تحدثنا عن عدة أمور لها علاقة بال
+
+6
+00:00:22,230 --> 00:00:25,170
+macroscopic examination وmicroscopic examination
+
+7
+00:00:25,870 --> 00:00:29,110
+وفي النهاية، تحدثنا عن الـVatility Test أو الـLife
+
+8
+00:00:29,110 --> 00:00:33,450
+Sperm Examination من خلال فحص الأيوزين أو
+
+9
+00:00:33,450 --> 00:00:38,150
+النجروسين استثنى استكمال لهذا الأمر، سوف نتكلم عن
+
+10
+00:00:38,150 --> 00:00:41,610
+الـHoss Test أو ما يُعرف باسم الـHypoosmotic
+
+11
+00:00:41,610 --> 00:00:45,770
+Swelling Test الـHypoosmotic Swelling Test، اختصار
+
+12
+00:00:45,770 --> 00:00:50,910
+Hoss Test وهو عبارة عن فحص يُستخدم للتفريغ ما بين
+
+13
+00:00:50,910 --> 00:00:56,570
+الحيوان المنوي الحيوالحيوان المنوي الميت وهو كفحص
+
+14
+00:00:56,570 --> 00:01:00,850
+مهم جدا خلال عملية ال fertilization لإنه أنا بهمني
+
+15
+00:01:00,850 --> 00:01:05,590
+أحقن الخلية بحيوان منوي حي حتى لو كان مش متحرك
+
+16
+00:01:05,590 --> 00:01:10,890
+فالمهم أن يكون حي The principle only living cell
+
+17
+00:01:10,890 --> 00:01:14,590
+with intact membrane will swell under hypoosmotic
+
+18
+00:01:14,590 --> 00:01:20,530
+condition 150 mO·L يعني المبدأ عمل هذا الفحص إن
+
+19
+00:01:20,530 --> 00:01:25,960
+الخلايا الحيةتميل إلى الـ swelling في حالة تعرضها
+
+20
+00:01:25,960 --> 00:01:30,480
+إلى الـ hypo osmotic condition يعني أنا أي خلية
+
+21
+00:01:30,480 --> 00:01:34,400
+حاططها في hypo osmotic condition هتنتفخ وهذه نفس
+
+22
+00:01:34,400 --> 00:01:39,360
+الفكرة في الـ host test أو الـ hypo osmotic
+
+23
+00:01:39,360 --> 00:01:44,540
+swelling the influx of a fluid into via pedicel is
+
+24
+00:01:44,540 --> 00:01:49,020
+reflected by the coiling of the sperm يعني ال
+
+25
+00:01:49,020 --> 00:01:53,080
+sperm إذا كان هذا ال sperm حيوضعته في hypo-osmotic
+
+26
+00:01:53,080 --> 00:01:57,640
+swelling or solution مباشرة، نهاية التل الخاصة فيه
+
+27
+00:01:57,640 --> 00:02:02,200
+هتنتفخ، معناه إن والله هذا ال sperm life، هذا ال
+
+28
+00:02:02,200 --> 00:02:07,660
+sperm available or lifeأحد أفضلات هذا الاختبار هو
+
+29
+00:02:07,660 --> 00:02:13,460
+أنه لا يقتل الفحص الذي يسمح بالتوليجة لهذا الفحص
+
+30
+00:02:13,460 --> 00:02:18,500
+للتكنولوجيا التجاربية يعني بمعنى أخر أن هذا الفحص
+
+31
+00:02:18,500 --> 00:02:21,480
+ما بيأثر على الفحص ما بيأثر على المادة الوراثية
+
+32
+00:02:21,480 --> 00:02:24,240
+بتاعة الفحص ما بيأثر على الـ function بتاعة الفحص
+
+33
+00:02:24,240 --> 00:02:28,640
+ما بيأثر على الكبسط بتاعة الفحص فبالتالي أي فحص
+
+34
+00:02:28,640 --> 00:02:32,600
+أخضعته لهذه العملية واتضح فيما بعد أن الـ life
+
+35
+00:02:32,600 --> 00:02:39,220
+ممكن أن أستخدمه في الـ Xبشكل مباشر بدون أي تردد In
+
+36
+00:02:39,220 --> 00:02:42,100
+this method, sperm sample should be mixed with the
+
+37
+00:02:42,100 --> 00:02:46,660
+hypoosmotic solution and incubated at 37 Celsius
+
+38
+00:02:46,660 --> 00:02:50,700
+for 30 minutes عشان انا اتأكد هذا ال sperm alive
+
+39
+00:02:50,700 --> 00:02:54,320
+ولا لا طب اذا كانت العينة بتستخدمها للإكزي يكفي
+
+40
+00:02:54,320 --> 00:02:59,910
+خمس دقائق تحضيرها بال hypoosmotic solutionبعد
+
+41
+00:02:59,910 --> 00:03:05,930
+عملية أحضين على 37 درجة مئوية لمدة 30 دقيقة أو
+
+42
+00:03:05,930 --> 00:03:11,150
+لمدة 5 دقائق باجي بعمل check up لل sperm أو بعد ال
+
+43
+00:03:11,150 --> 00:03:16,070
+sperm بعمل with preparation على ال slide should be
+
+44
+00:03:16,070 --> 00:03:19,170
+made and assess the sample under phase contrast
+
+45
+00:03:19,170 --> 00:03:23,630
+microscope على عدسة تكبير 400 أو 200 بعيد 200
+
+46
+00:03:23,630 --> 00:03:28,330
+sperm بشوف مين فيهم life و مين فيهم deadبناء على
+
+47
+00:03:28,330 --> 00:03:34,450
+الانتفاخ اللي يظهر أسفل الذئب في هذا الشكل طبعا دي
+
+48
+00:03:34,450 --> 00:03:37,890
+اللي على اليسار رقم A هي عبارة عن ال fertility
+
+49
+00:03:37,890 --> 00:03:42,590
+test بفعل النجروسين أو ال Iosin بضيف I قطرة من ال
+
+50
+00:03:42,590 --> 00:03:46,170
+Iosin بضيف قطرة من النجروسين و بضيف قطرة من السيمن
+
+51
+00:03:46,170 --> 00:03:50,450
+بعمله mix او واحد سيمن اتنين drop Iosin اتنين drop
+
+52
+00:03:50,450 --> 00:03:54,170
+نجروسين بعمل mix و بشوفها تحت الميكروسكوب اللي
+
+53
+00:03:54,170 --> 00:04:00,980
+بالشب هو ال lifeأما الأخر صفقة الـ Iosin هو الـ
+
+54
+00:04:00,980 --> 00:04:05,340
+dead أو الـ non-viable اللي على اليسار هي عبارة عن
+
+55
+00:04:05,340 --> 00:04:09,700
+الـ hypo osmotic swelling test الـ host test بضيف
+
+56
+00:04:09,700 --> 00:04:14,140
+sample من الـ seminal fluid بضيف عليه الـ hypo
+
+57
+00:04:14,140 --> 00:04:18,180
+osmotic swelling fluid or solution وبعمل mixing
+
+58
+00:04:18,180 --> 00:04:24,900
+وincubation لمدة 30 أو 5 دقائقعلى 37 درجة مهوية أي
+
+59
+00:04:24,900 --> 00:04:29,440
+sperm بظهر لـ swelling في أسفله هذا معناه normal
+
+60
+00:04:29,440 --> 00:04:32,280
+sperm swelling زي ما أحنا شايفينه على جهة اليسار
+
+61
+00:04:32,280 --> 00:04:36,840
+في منطقة التل بسميه normal sperm viable sperm أما
+
+62
+00:04:36,840 --> 00:04:39,800
+إذا كان مافيه swelling في نهاية التل فهو عبارة عن
+
+63
+00:04:39,800 --> 00:04:45,420
+non viable sperm أو dead sperm هذا الفرق ما بين
+
+64
+00:04:45,420 --> 00:04:50,220
+الفرقتانفي طريقة تانية وهي طريقة العدو معتمدة على
+
+65
+00:04:50,220 --> 00:04:54,480
+الكمبيوتر بنسميها Computerized
+
+66
+00:04:54,480 --> 00:05:00,560
+Assisted Sperm Analysis أو Computer Assisted Sperm
+
+67
+00:05:00,560 --> 00:05:07,840
+Analysis تحت مصطلح كذا كذا C للكمبيوتر A Assisted
+
+68
+00:05:07,840 --> 00:05:12,940
+Sperm Analysis يعني أنت كتكنيشن ما بتشتغل شيء إلا
+
+69
+00:05:12,940 --> 00:05:16,360
+بتعمل weight mount يعني كتانك تضيف خمسين micro من
+
+70
+00:05:16,730 --> 00:05:19,590
+عينة الـ Similar Fluid بعد الـ mix الجيد و بتغطيها
+
+71
+00:05:19,590 --> 00:05:22,930
+بـ cover slide و بتدخلها تحت ال microscope و ال
+
+72
+00:05:22,930 --> 00:05:26,550
+microscope بناء على software معين بيقرأ كل ال
+
+73
+00:05:26,550 --> 00:05:29,870
+field بيهدلك ال sperm و بيجيبلك ال motility و
+
+74
+00:05:29,870 --> 00:05:34,130
+بيجيبلك ال morphology حتى بيجيبلك تصنيف ال motile
+
+75
+00:05:34,130 --> 00:05:37,830
+هى ال progressive و لا non progressive motile ولكن
+
+76
+00:05:37,830 --> 00:05:42,410
+خد بالك أنه لازمبنعمل check-up على نتائجه لأن في
+
+77
+00:05:42,410 --> 00:05:47,270
+نسبة خطأ منها بفعل أن بعض الـ Depress ممكن يعدها ك
+
+78
+00:05:47,270 --> 00:05:56,030
+Spare خلينا نشوف الفيديو متعلق بعد الموضوع نشوف
+
+79
+00:05:56,030 --> 00:05:59,030
+الفيديو Motility and concentration sample
+
+80
+00:05:59,030 --> 00:06:03,290
+preparation First step is to prepare a sample for
+
+81
+00:06:03,290 --> 00:06:05,410
+motility and concentration analysis
+
+82
+00:06:12,750 --> 00:06:13,950
+يمكن استخدام بطاريات مستخدمة يمكن استخدامها
+
+83
+00:06:13,950 --> 00:06:16,590
+بطاريات مستخدمة يمكن استخدامها بطاريات مستخدمة
+
+84
+00:06:16,590 --> 00:06:20,710
+يمكن استخدامها بطاريات مستخدمة يمكن استخدامها
+
+85
+00:06:20,710 --> 00:06:21,250
+بطاريات مستخدمة يمكن استخدامها بطاريات مستخدمة
+
+86
+00:06:21,250 --> 00:06:23,670
+يمكن استخدامها بطاريات مستخدمة يمكن استخدامها
+
+87
+00:06:23,670 --> 00:06:27,550
+بطاريات مستخدمة يمكن استخدامها بطاريات مستخدمة
+
+88
+00:06:27,550 --> 00:06:29,270
+يمكن استخدامها بطاريات مستخدمة يمكن استخدامها
+
+89
+00:06:29,270 --> 00:06:31,470
+بطاريات مستخدمة يمكن استخدامها بطاريات مستخدمة
+
+90
+00:06:31,470 --> 00:06:36,270
+يمكن استخدامها بطاريات مستخدمة يمكن استخ
+
+91
+00:06:40,810 --> 00:06:45,450
+ثم إزالة المواصفات المكسورة السلسلة مستعدة للتعامل
+
+92
+00:06:45,450 --> 00:06:50,150
+معها مقاطع الميكروسكوبللتحديث الموتولوجيا
+
+93
+00:06:50,150 --> 00:06:54,150
+والتركيزية سنستخدم الـ Green Filter، الـ Condenser
+
+94
+00:06:54,150 --> 00:06:59,490
+في موقع PH1 و10X Face Consciousness Objective تذكر
+
+95
+00:06:59,490 --> 00:07:02,650
+أنه ممكن أيضًا أن تستخدم الـ Fluorescence
+
+96
+00:07:02,650 --> 00:07:06,870
+موتولوجيا والتركيزية تستخدم الـ Fluorescence It is
+
+97
+00:07:06,870 --> 00:07:09,670
+possible to access the analysis module from the
+
+98
+00:07:09,670 --> 00:07:12,670
+respective button in results tab or from the icons
+
+99
+00:07:12,670 --> 00:07:16,810
+bar In this window, the user can choose different
+
+100
+00:07:16,810 --> 00:07:20,760
+analysis configurationsThis is the main analysis
+
+101
+00:07:20,760 --> 00:07:23,540
+window where the sample information is presented
+
+102
+00:07:23,540 --> 00:07:28,400
+Press analyze to start Live image is displayed
+
+103
+00:07:28,400 --> 00:07:34,420
+focus طبعا هنا ضاف العينة وشغل الميكروسكوب وعمل
+
+104
+00:07:34,420 --> 00:07:38,000
+analysis فجاب ال field أخد capture الميكروسكوب
+
+105
+00:07:38,000 --> 00:07:41,100
+فيما بعد ببدأ أو الكمبيوتر ببدأ يعد ال sperm
+
+106
+00:07:41,100 --> 00:07:47,140
+الموجودة في هذا ال capture بناء علىطبعاً عدد و
+
+107
+00:07:47,140 --> 00:07:53,220
+Parameter معينة و طول و عرض خاصة بالhead بعد كده
+
+108
+00:07:53,220 --> 00:07:55,600
+بياخد أكتر من ال capture و بيقارنهم مع بعض و مع
+
+109
+00:07:55,600 --> 00:08:00,740
+بعض علشان يشوف مين المتايل و مين المش متايل spare
+
+110
+00:08:00,740 --> 00:08:04,220
+fill and start the analysis clicking again the
+
+111
+00:08:04,220 --> 00:08:08,560
+analyze button main analysis information is always
+
+112
+00:08:08,560 --> 00:08:12,760
+present on this side or capture sequences can be
+
+113
+00:08:12,760 --> 00:08:17,250
+played in the analysis user tabباستخدام مانيال
+
+114
+00:08:17,250 --> 00:08:18,930
+النتائج، يمكن المستخدم أن يختار مقاطع الـSperm
+
+115
+00:08:18,930 --> 00:08:22,830
+مختلفة ويقوم بمعرفة أو لا معرفة أي Spermatozoa تم
+
+116
+00:08:22,830 --> 00:08:25,850
+إظهارها
+
+117
+00:08:25,850 --> 00:08:33,950
+.من
+
+118
+00:08:33,950 --> 00:08:36,790
+الممكن أيضًا أن تشاهد المعلومات عن واحدة Sperm
+
+119
+00:08:36,790 --> 00:08:42,260
+بمضغط عينيها وفتح مقاطع الـSperm Infoبنقل إلى
+
+120
+00:08:42,260 --> 00:08:44,100
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+121
+00:08:44,100 --> 00:08:46,600
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+122
+00:08:46,600 --> 00:08:49,960
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+123
+00:08:49,960 --> 00:08:55,400
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+124
+00:08:55,400 --> 00:08:55,500
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+125
+00:08:55,500 --> 00:08:55,600
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+126
+00:08:55,600 --> 00:09:05,720
+نتيجة نتيجة نتيجة نتيجة نتيجة نتيجة
+
+127
+00:09:05,720 --> 00:09:10,080
+نتيج
+
+128
+00:09:10,580 --> 00:09:13,360
+أتابع مع المعلومات عن مصادرها الـ Spermatozoon
+
+129
+00:09:13,360 --> 00:09:28,380
+وخلاصًا
+
+130
+00:09:28,380 --> 00:09:32,040
+مصادر تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+131
+00:09:32,040 --> 00:09:33,260
+تجارب تجارب تجارب
+
+132
+00:09:41,070 --> 00:09:44,770
+هو بسهولة جدًا للوصول إلى مقال التجارب اللي يمكن
+
+133
+00:09:44,770 --> 00:09:55,650
+أن يتم تحميله لأي مصمم التجارب التجاربية
+
+134
+00:09:55,650 --> 00:09:57,210
+يمكن أن يتم تحميله لأي مصمم التجارب التجاربية
+
+135
+00:09:57,210 --> 00:10:00,650
+التجاربية يمكن أن يتم تحميله لأي مصمم التجارب
+
+136
+00:10:00,650 --> 00:10:02,630
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+137
+00:10:02,630 --> 00:10:03,230
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+138
+00:10:03,230 --> 00:10:03,310
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+139
+00:10:03,310 --> 00:10:03,710
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+140
+00:10:03,710 --> 00:10:09,650
+التجاربية التجاربية التجاربية التجاربية التجارب
+
+141
+00:10:14,380 --> 00:10:18,700
+إذا هذه فكرة الكازة و هي ال computer assist sperm
+
+142
+00:10:18,700 --> 00:10:22,200
+analysis إنه أنا ك technician ما بشغل شيء بيدي و
+
+143
+00:10:22,200 --> 00:10:25,320
+جرد إن بحضر ال sample من خلال وضع خمسين micro أو
+
+144
+00:10:25,320 --> 00:10:28,740
+عشرة micro بناء على ال protocol المستخدم و بعدين
+
+145
+00:10:28,740 --> 00:10:31,220
+بضيفه تحت ال fluorescent microscope أو ال face
+
+146
+00:10:31,220 --> 00:10:34,840
+contrast microscope على عدسة عشرة بعدين بعمل
+
+147
+00:10:34,840 --> 00:10:38,640
+switch on للجهاز و بخليه ياخد capture و 2 و 3 و 4
+
+148
+00:10:39,000 --> 00:10:42,500
+بعدين بدأت على ال analysis عشان يبدأ الجهاز يحلل
+
+149
+00:10:42,500 --> 00:10:46,100
+الصور اللي أخدهم أكتر من مرة بيديني ال utility،
+
+150
+00:10:46,100 --> 00:10:48,520
+بيديني أنواعها، بيديني ال concentration، بيديني ال
+
+151
+00:10:48,520 --> 00:10:51,540
+total count، بيديني ال morphology، بناء على شو أنا
+
+152
+00:10:51,540 --> 00:10:54,720
+بدي براميتر كلها متوفرة، بناء على ال program
+
+153
+00:10:54,720 --> 00:10:59,130
+المستخدم، كل شركة لها program خاص فيهاخدوا بالكوا
+
+154
+00:10:59,130 --> 00:11:03,030
+الكازم ما بيستخدم في الـ routine lab أو اللي بيقول
+
+155
+00:11:03,030 --> 00:11:06,790
+كمية العيلة بتجي لها خمسة، ستة، سبعة، تمانية في
+
+156
+00:11:06,790 --> 00:11:12,030
+اليوم لأ بيستخدم في المختبرات الكبيرة اللتي يوجد
+
+157
+00:11:12,030 --> 00:11:16,190
+عندها ضغط كبير من العمل أو مختبرات اللي لها علاقة
+
+158
+00:11:16,190 --> 00:11:20,370
+بال research المتعلق في ال anthropology هذه فكرة
+
+159
+00:11:20,370 --> 00:11:25,470
+الكازم الفكرة التانية اللي بتتكلم عنها كيف تعمل
+
+160
+00:11:25,470 --> 00:11:29,850
+evaluation لل sperm DNAطبعا ال sperm اعرفته انه
+
+161
+00:11:29,850 --> 00:11:33,590
+life ال sperm اعرفته انه motile هل ال sperm DNA
+
+162
+00:11:33,590 --> 00:11:37,710
+جيد فيه damage في ال sperm DNA لأنه ممكن ال sperm
+
+163
+00:11:37,710 --> 00:11:43,210
+يكون motile ويكون life ولكن ال capacity تبعته مش
+
+164
+00:11:43,210 --> 00:11:47,350
+هال capacity و ال DNA تبعته صار فيها fragmentation
+
+165
+00:11:47,350 --> 00:11:50,790
+فبالتالي لو عمل fertilization ممكن يؤدي إلى إجهاض
+
+166
+00:11:50,790 --> 00:11:56,480
+الجنيه لأنه ما ارتقى إلىالكيف والكم المناسب لإتمام
+
+167
+00:11:56,480 --> 00:12:00,180
+عملية ال fertilization بالشكل المطلوب تحت مصطلح
+
+168
+00:12:00,180 --> 00:12:03,680
+evaluation of sperm DNA damage the maintenance of
+
+169
+00:12:03,680 --> 00:12:08,160
+sperm DNA integrity is vital for fertilized and to
+
+170
+00:12:08,160 --> 00:12:10,440
+transmitted the genetic material from one
+
+171
+00:12:10,440 --> 00:12:13,880
+generation to another لأن المادة الوراثية هي عبارة
+
+172
+00:12:13,880 --> 00:12:18,800
+عن جوهر العملية ال fertilization تصير عشان ينقل
+
+173
+00:12:18,800 --> 00:12:23,350
+المادة النووية الخاصة بالأب إلىالمادة النووية
+
+174
+00:12:23,350 --> 00:12:26,810
+الخاصة بالقمج تكوين الزيجوت إذا كان هذا المادة
+
+175
+00:12:26,810 --> 00:12:29,550
+النووية فيها مشكلة معناه الزيجوت اللي اتكوّنت
+
+176
+00:12:29,550 --> 00:12:34,310
+حتصير فيها مشكلة معناه فرصة ال up portion هتزيد ال
+
+177
+00:12:34,310 --> 00:12:37,850
+sperm chromatin undergoes extensive remodeling
+
+178
+00:12:37,850 --> 00:12:43,430
+during spermatogenesis to protect sperm DNA بمعنى
+
+179
+00:12:43,430 --> 00:12:46,590
+آخر إن هذا ال DNA الموجود داخل ال sperm في ال head
+
+180
+00:12:46,590 --> 00:12:50,450
+تاع ال sperm فيه عند ال chromatinالقرمتين الموجود
+
+181
+00:12:50,450 --> 00:12:53,970
+هناك بيصير له عملية كبيرة جدا من الـ remedulling
+
+182
+00:12:53,970 --> 00:12:58,050
+علشان يحافظ على ال sperm و يحمل مادة نوية لخاصة
+
+183
+00:12:58,050 --> 00:13:02,690
+بال sperm من التكسير أو من التلف إذا ما صارش إلها
+
+184
+00:13:02,690 --> 00:13:06,130
+remedulling معناه فيه defect حيصير على صعيد ال
+
+185
+00:13:06,130 --> 00:13:10,410
+sperm DNA in this process most of sperm DNA
+
+186
+00:13:10,410 --> 00:13:14,610
+hostone should be replaced with protamine Iو
+
+187
+00:13:14,610 --> 00:13:19,050
+البروتامين 2 و كمية صغيرة من البروتامين يجب أن
+
+188
+00:13:19,050 --> 00:13:24,530
+تبقى موجودة في الديانة، في المبالغة هذه العملية
+
+189
+00:13:24,530 --> 00:13:27,550
+مهمة جدا أنه إذا كان عندك كمية كبيرة جدا من
+
+190
+00:13:27,550 --> 00:13:31,550
+البروتامين كبروتين هذا البروتامين سوف يستبدل
+
+191
+00:13:31,550 --> 00:13:35,790
+بالبروتامين 1 وبروتامين 2 و لازم ما يتبقى من
+
+192
+00:13:35,790 --> 00:13:40,310
+البروتامين إلا كمية قليلة جدا جدا جدا لو لم تحدث
+
+193
+00:13:40,310 --> 00:13:44,760
+هذه العملية عملية البروتامين replacementهيكون فيه
+
+194
+00:13:44,760 --> 00:13:47,800
+end effect في الـ structure of DNA في الـ
+
+195
+00:13:47,800 --> 00:13:50,720
+spermatogenesis، معناه الـ sperm لن يؤدي الوظيفة
+
+196
+00:13:50,720 --> 00:13:55,140
+المطلوبة منه if this event don't occur probably
+
+197
+00:13:55,140 --> 00:13:58,240
+endospermatozoa will retain more or save more
+
+198
+00:13:58,240 --> 00:14:01,460
+histone than they should sperm DNA become more
+
+199
+00:14:01,460 --> 00:14:04,060
+sensitive to damaging هذا الكلام اللي حكيته قبل
+
+200
+00:14:04,060 --> 00:14:07,560
+بشوية إنه يجب أن تتم عملية استبدال الهستون
+
+201
+00:14:07,560 --> 00:14:11,300
+بالبروتامين 1 وبروتامين 2 ويبقى الهستون بكمية
+
+202
+00:14:11,300 --> 00:14:14,830
+قليلة جدا جدا جدا داخل ال spermإذا لم تحدث هذه
+
+203
+00:14:14,830 --> 00:14:18,450
+العملية، معناه إن الـDNA الموجود داخل الـSperm
+
+204
+00:14:18,450 --> 00:14:23,230
+هيكون أكثر حساسية للتلف والتكسير طيب، شو اللي
+
+205
+00:14:23,230 --> 00:14:27,250
+هيكسر؟ وشو هيخليه عرض للتلف؟ بقول الـDNA الـdamage
+
+206
+00:14:27,250 --> 00:14:31,090
+can occur only during spermatogenesis أكيد، but
+
+207
+00:14:31,090 --> 00:14:35,610
+also during storage in epidermis or transport from
+
+208
+00:14:35,610 --> 00:14:39,310
+one place to another يعني معنى آخر إن الـSperm
+
+209
+00:14:39,310 --> 00:14:43,950
+طالما خُلقولم يحدث له عن أي مشكلة خلال عمل التخليق
+
+210
+00:14:43,950 --> 00:14:49,470
+أنه بيكون فيه أمان وفيه مكان مأمون عن المخاطر لأ
+
+211
+00:14:49,470 --> 00:14:53,150
+ممكن يتعرض إلى external factor أو another factor
+
+212
+00:14:53,150 --> 00:14:56,330
+خلال عملية التخزين في الepidermis أو خلال عملية ال
+
+213
+00:14:56,330 --> 00:14:59,650
+ejaculation أو خلال ال transfer من منطقة إلى منطقة
+
+214
+00:14:59,650 --> 00:15:04,020
+يودي إلى تلفد يعنيمن أشهر العوامل التي تؤدي إلى
+
+215
+00:15:04,020 --> 00:15:07,460
+DNA damage هي عبارة عن Oxidative Stress اللي
+
+216
+00:15:07,460 --> 00:15:11,680
+بتسميه OS شو يعني Oxidative Stress؟ ببساطة في
+
+217
+00:15:11,680 --> 00:15:15,160
+أجسامنا في حاجة اسمها Free Radical وفي حاجة اسمها
+
+218
+00:15:15,160 --> 00:15:18,020
+Antioxidant لازم يصير فيه balance ما بين ال
+
+219
+00:15:18,020 --> 00:15:23,200
+antioxidantو ال free radical إذا صار في عندي
+
+220
+00:15:23,200 --> 00:15:26,200
+imbalance ما بين ال free radical و ال antioxidant
+
+221
+00:15:26,200 --> 00:15:30,520
+حيصير عندي حالة بنسميها oxidative stress oxidative
+
+222
+00:15:30,520 --> 00:15:33,460
+stress is one of the most common intrinsic factors
+
+223
+00:15:33,460 --> 00:15:37,640
+leading to sperm DNA damage but it may also result
+
+224
+00:15:37,640 --> 00:15:42,440
+from pathogenic status of the reproductive system
+
+225
+00:15:42,440 --> 00:15:48,610
+برجع بقول مرة تانيةالـ Oxidative Stress ينتج من
+
+226
+00:15:48,610 --> 00:15:52,750
+خلال عدم وجود اتزان ما بين كمية الـ Antioxidant
+
+227
+00:15:52,750 --> 00:15:56,890
+الموجودة في أجسامنا و الـ Free Radical و الأكتر
+
+228
+00:15:56,890 --> 00:16:01,590
+تخصيص عدم وجود اتزان ما بين كمية الـ Antioxidant و
+
+229
+00:16:01,590 --> 00:16:04,470
+الـ Free Radical الموجودة في سمن الفلويد فواحد
+
+230
+00:16:04,470 --> 00:16:08,310
+بزيد عن التاني هيعطيني Oxidative Stress Oxidative
+
+231
+00:16:08,310 --> 00:16:12,620
+Stress يعتبر من أشهر وأكترالأسباب المسببة إلى
+
+232
+00:16:12,620 --> 00:16:16,800
+تكسير و تلف المادة الوراطية الخاصة بالـ sperm ولكن
+
+233
+00:16:16,800 --> 00:16:21,940
+هناك عوام الأخرى لها علاقة بالأمراض المتعلقة بالـ
+
+234
+00:16:21,940 --> 00:16:28,680
+Mere Reproductive System حوالي 25% زيادة من الـ
+
+235
+00:16:28,680 --> 00:16:33,940
+reactive oxidase species اللي سمنها free radical
+
+236
+00:16:33,940 --> 00:16:38,030
+25% increase in seminalمعنى الـ Reactive Oxygen
+
+237
+00:16:38,030 --> 00:16:43,070
+Species Level مرتبط بـ 10% تزيد في عدد الـ Sperm
+
+238
+00:16:43,070 --> 00:16:47,190
+DNA Fragmentation يعني عندي لو زاد الـ Reactive
+
+239
+00:16:47,190 --> 00:16:53,050
+Oxygen Species اللي سميتها Free Radical 25% ستكون
+
+240
+00:16:53,050 --> 00:16:59,970
+سبب في تدمير 10% من الـ Sperm DNA تحت مصطلح DNA
+
+241
+00:16:59,970 --> 00:17:04,790
+Fragmentation بمعدل 10% DNA Damage can affect both
+
+242
+00:17:04,790 --> 00:17:09,940
+Nuclear DNAوMitochondrial DNA يعني بمعنى آخر أن
+
+243
+00:17:09,940 --> 00:17:13,760
+الـ Oxidative Stress لن يؤثر فقط على الـ Nucleic
+
+244
+00:17:13,760 --> 00:17:16,500
+Acid الموجود في الـ head، في الـ Nuclear ولكن
+
+245
+00:17:16,500 --> 00:17:19,040
+هيؤثر أيضًا على الـ Nucleic Acid الموجود في الـ
+
+246
+00:17:19,040 --> 00:17:23,300
+Mitochondria Oxidative Stress induced damage to
+
+247
+00:17:23,300 --> 00:17:27,180
+Nuclear DNA may accelerate germ cell apoptosis
+
+248
+00:17:27,180 --> 00:17:30,300
+leading to decline in sperm production and
+
+249
+00:17:30,300 --> 00:17:35,080
+consequently decrease sperm count in ejaculationلو
+
+250
+00:17:35,080 --> 00:17:38,440
+حصل فيه stress إكسيداتيه سيدمر ال DNA الموجودة في
+
+251
+00:17:38,440 --> 00:17:42,120
+نوات ال sperm فبالتالي سيسرق تواجه ال sperm إلى
+
+252
+00:17:42,120 --> 00:17:46,120
+Epiptosis معناه سيصير نقصان في عدد ال sperm
+
+253
+00:17:46,120 --> 00:17:50,760
+الموجود في ال ejaculation معناه في عندي ببساطة جدا
+
+254
+00:17:50,760 --> 00:17:54,640
+نقصان في كمية ال sperm المخلق معناه في عندي نقصان
+
+255
+00:17:54,640 --> 00:17:58,780
+في ال sperm count يعني one step another step go to
+
+256
+00:17:58,780 --> 00:18:02,080
+another step a positive sum study
+
+257
+00:18:13,420 --> 00:18:18,640
+معناه زيادة الـ sperm DNA fragmentation متعلق
+
+258
+00:18:18,640 --> 00:18:22,440
+بزيادة الـ abnormal في الـ sperm morphology و
+
+259
+00:18:22,440 --> 00:18:26,820
+بالذات في الـ sperm تاني في دراسة أخرى قالت إنه في
+
+260
+00:18:26,820 --> 00:18:30,800
+عندي higher incidence of aneuploidy in manin men
+
+261
+00:18:30,800 --> 00:18:34,520
+or males with high spare DNA fragmentation ال
+
+262
+00:18:34,520 --> 00:18:40,120
+incidence تبع الانبلويدي في الذكور بيزيد لو زاد
+
+263
+00:18:40,120 --> 00:18:46,160
+عندي ال DNA fragmentation هذه شكل أخر ودراسة أخرى
+
+264
+00:18:46,160 --> 00:18:50,800
+وجدت أن ال higher incidence of anibluity في الذكور
+
+265
+00:18:50,800 --> 00:18:58,480
+مرتبط بالhigh spare DNA fragmentation صورة بتوضح
+
+266
+00:18:58,480 --> 00:19:02,580
+الكلام اللي اتكلمنا عنههذا الـ sperm في أعلى الـ
+
+267
+00:19:02,580 --> 00:19:06,000
+slide sperm، normal sperm بيصيرله capacitation
+
+268
+00:19:06,000 --> 00:19:09,260
+بيصير عندي acrosome reaction بيصير عندي
+
+269
+00:19:09,260 --> 00:19:12,880
+hyperactivation يعني بيصير عندي fertilization ما
+
+270
+00:19:12,880 --> 00:19:15,960
+بيصير fertilization إلا إذا صارت capacitation وهو
+
+271
+00:19:15,960 --> 00:19:19,900
+تحول ال sperm إلى completely mature sperm بعدين
+
+272
+00:19:19,900 --> 00:19:23,960
+بيصير acrosome reaction من خلال اتصال ال sperm مع
+
+273
+00:19:23,960 --> 00:19:26,440
+الـ receptor الموجودة في الزنا باليسود رقم 3
+
+274
+00:19:26,440 --> 00:19:30,430
+وإفراز إنزيماته الهاضمةبعدين بيصير الـ
+
+275
+00:19:30,430 --> 00:19:33,950
+hyperactivation و هي عبارة عن زيادة الحركة مما
+
+276
+00:19:33,950 --> 00:19:36,630
+يسمح للـ sperm باختراق الـ void بتصير
+
+277
+00:19:36,630 --> 00:19:40,510
+fertilization تصور صار عندك imbalance ما بين الـ
+
+278
+00:19:40,510 --> 00:19:43,710
+free radical reactive oxygen species و ال
+
+279
+00:19:43,710 --> 00:19:47,790
+antioxidant هتعطيلي حالة بنسميها oxidative stress
+
+280
+00:19:47,790 --> 00:19:51,570
+هذا ال oxidative stress مصدرها قد يكون أسبابها
+
+281
+00:19:51,570 --> 00:19:55,830
+خارجية زي ال smoking زي ال radiation زي الكحول و
+
+282
+00:19:55,830 --> 00:19:59,400
+زي المواد التكسيديةوقد تكون داخلية زي الـ
+
+283
+00:19:59,400 --> 00:20:04,060
+Varicosel دوال الخصية زي الـ Leukocyte زيادة في
+
+284
+00:20:04,060 --> 00:20:06,700
+عدد Leukocyte يعني الـ inflammation وزي ال
+
+285
+00:20:06,700 --> 00:20:11,600
+immature spermatozoa خدوا بالكم النقطة التهاب
+
+286
+00:20:11,600 --> 00:20:16,460
+وزيادة عدد الحيوانات المنوية الغير ناضجة يؤدي إلى
+
+287
+00:20:16,460 --> 00:20:20,080
+زيادة عدد الرُس زيادة عدد الرُس تعتبر من أهم
+
+288
+00:20:20,080 --> 00:20:23,840
+العوامل التي تؤدي إلى الـ oxidative stress طب صار
+
+289
+00:20:23,840 --> 00:20:27,890
+في oxidative stress إيش هيسوي؟هيعمل على تعطيل الـ
+
+290
+00:20:27,890 --> 00:20:31,410
+physiological rules الخاصة بالـ sperm هتعطل
+
+291
+00:20:31,410 --> 00:20:34,810
+الcapacitation، هتعطل الacrosome reaction، هتعطل
+
+292
+00:20:34,810 --> 00:20:38,070
+الhyperactivity، يعني مافيه fertilization أضف إلى
+
+293
+00:20:38,070 --> 00:20:42,310
+ذلك، هتعمل apoptosis، هتعمل DNA damage على صحيح
+
+294
+00:20:42,310 --> 00:20:47,590
+الـDNA، هتعمل مشاكل في الـ lipid protein الموجودة
+
+295
+00:20:47,850 --> 00:20:52,730
+في الـ peroxidation الخاصة بالـ sperm فبالتالي الـ
+
+296
+00:20:52,730 --> 00:20:57,070
+infertility بتكون أقرب في هذه الحالة إلى الذكورة
+
+297
+00:20:57,070 --> 00:21:01,030
+Alteration in mitochondria sperm DNA mainly led to
+
+298
+00:21:01,030 --> 00:21:04,470
+impaired mitochondrial function those resulting in
+
+299
+00:21:04,470 --> 00:21:08,030
+the homotility abnormality, hyperactivity
+
+300
+00:21:08,030 --> 00:21:11,310
+abnormality, inability to fertilization يعني بمعنى
+
+301
+00:21:11,310 --> 00:21:16,030
+أخر ليس الخطر مرتبط بالدمج في ال sperm nuclear DNA
+
+302
+00:21:16,510 --> 00:21:19,990
+ولكن لو حد رزد دمش في ال sperm يتقندر ال DNA، هذا
+
+303
+00:21:19,990 --> 00:21:22,670
+معناه هيوقف ال motility، هتكون ال motility غير
+
+304
+00:21:22,670 --> 00:21:28,610
+متكافئة، غير سليمة، غير صحيحة، غير مطلوبة ال
+
+305
+00:21:28,610 --> 00:21:32,570
+hyperactivity هيصير فيها defect، هيصير غير قادر
+
+306
+00:21:32,570 --> 00:21:35,970
+على ال fertilization زي ما شفنا في ال slide السابق
+
+307
+00:21:45,480 --> 00:21:54,500
+الفرصة اللي تبقى
+
+308
+00:21:54,500 --> 00:21:58,060
+محدودة
+
+309
+00:21:58,060 --> 00:22:01,000
+في الـ sperm DNA لإصلاح المزيد من المزيد من المزيد
+
+310
+00:22:01,000 --> 00:22:01,000
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+311
+00:22:01,000 --> 00:22:01,000
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+312
+00:22:01,000 --> 00:22:01,000
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+313
+00:22:01,000 --> 00:22:01,000
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+314
+00:22:01,000 --> 00:22:01,000
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+315
+00:22:01,000 --> 00:22:01,000
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+316
+00:22:01,000 --> 00:22:01,000
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+317
+00:22:01,000 --> 00:22:01,000
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+318
+00:22:01,000 --> 00:22:01,000
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+319
+00:22:01,000 --> 00:22:03,160
+من المزيد من المزيدو Damage في الـ DNA معناه
+
+320
+00:22:03,160 --> 00:22:06,260
+البروتينات الموجودة في الـ Spare هتفقد وظيفتها
+
+321
+00:22:06,260 --> 00:22:10,200
+معناه الـ Spare هيفقد وظيفته The available method
+
+322
+00:22:10,200 --> 00:22:13,280
+we can use it to detect the DNA damage
+
+323
+00:22:13,280 --> 00:22:17,080
+fragmentation or apoptosis عندي تلت طرق Measured
+
+324
+00:22:17,080 --> 00:22:22,400
+DNA damage by incorporating DNA probe Measured the
+
+325
+00:22:22,400 --> 00:22:26,580
+sensitivity of DNA to denaturationindirect
+
+326
+00:22:26,580 --> 00:22:30,300
+measures of level chromatin compaction هذه التلت
+
+327
+00:22:30,300 --> 00:22:34,640
+عوامل أساسية هناخد تنتين مهمين جدا و لازم يتم
+
+328
+00:22:34,640 --> 00:22:39,080
+إجراءهم في مراكز التوضيح الصناعي So what is the
+
+329
+00:22:39,080 --> 00:22:42,620
+type of DNA damage؟ according to the type بقدر
+
+330
+00:22:42,620 --> 00:22:46,380
+أحدد ال test أول حاجة DNA fragmentationوالـ DNA
+
+331
+00:22:46,380 --> 00:22:50,380
+Fragmentation في عوامل أخرى كثيرة تساهم فيه منها
+
+332
+00:22:50,380 --> 00:22:53,220
+الـ Intrinsic أو الـ Extrinsic Factor الـ
+
+333
+00:22:53,220 --> 00:22:56,600
+Intrinsic Factor التي تؤدي إلى DNA Fragmentation
+
+334
+00:22:56,600 --> 00:23:01,980
+والذي يعتبر أحد أنواع الـ DNA Damaged Epitosis and
+
+335
+00:23:01,980 --> 00:23:05,620
+Oxidative Stress وحكينا عنها الـ Defect في الـ
+
+336
+00:23:05,620 --> 00:23:08,140
+Protamination وهي عملية استبدال الـ stone
+
+337
+00:23:08,140 --> 00:23:13,220
+بالبروتامين لأن وجود البروتامين مهم جدا لحمايةDNA
+
+338
+00:23:13,220 --> 00:23:17,480
+of spermatozoa Insufficient chromatin remodeling
+
+339
+00:23:17,480 --> 00:23:20,780
+خلل في الـ spermatogenesis إذا الأربع عوامل
+
+340
+00:23:20,780 --> 00:23:26,400
+الأساسية تصنف intrinsic factor تعمل على و تساهم في
+
+341
+00:23:26,400 --> 00:23:30,420
+حدوث الـ DNA fragmentation الذي يعتبر أحد أنواع
+
+342
+00:23:30,420 --> 00:23:33,830
+الـ DNA damageالعوامل الأخرى بنسميها external
+
+343
+00:23:33,830 --> 00:23:38,530
+factors زي ال life style زي الـ diet و ال drug
+
+344
+00:23:38,530 --> 00:23:43,110
+consuming و ال tobacco، cigarette smoking، الشيشة،
+
+345
+00:23:43,110 --> 00:23:46,330
+ال advancing age زيادة العمر، ال environment
+
+346
+00:23:46,330 --> 00:23:50,770
+exposure زي ال pesticide و ال pollution، بعض ال
+
+347
+00:23:50,770 --> 00:23:53,430
+medical history زي ال inflammation و الفارقوسيل و
+
+348
+00:23:53,430 --> 00:23:58,420
+ال cancerدول الأربع يعتبروا external factor تساهم
+
+349
+00:23:58,420 --> 00:24:02,600
+في إحداث DNA fragmentation الذي يعتبر أحد أنواع
+
+350
+00:24:02,600 --> 00:24:08,360
+الـ DNA damage صورة بتوضح الكلام اللي احنا اتكلمنا
+
+351
+00:24:08,360 --> 00:24:14,220
+عنه في sperm and sperm DNA damage بيصير بفعل أول
+
+352
+00:24:14,220 --> 00:24:18,480
+حاجة ال aging advanced aging infection cancer
+
+353
+00:24:18,480 --> 00:24:24,360
+toxic material radiation pollutionCaffeine Intake
+
+354
+00:24:24,360 --> 00:24:30,100
+Body Mass Index Malnutrition Poor Diet Alcohol
+
+355
+00:24:30,100 --> 00:24:34,560
+Stress Smoking Increase in testicular temperature
+
+356
+00:24:34,560 --> 00:24:37,360
+و البركوسيلة عشان كده الناس اللي بتشتغل في المخابز
+
+357
+00:24:37,360 --> 00:24:40,520
+القديمة و الناس اللي بتشتغل في مصانع الاسفنج و
+
+358
+00:24:40,520 --> 00:24:43,560
+بتتعرض لكمية كبيرة جدا من الحرارة بتكون أقرب لل
+
+359
+00:24:43,560 --> 00:24:48,700
+infertility بفيها الحدوث اتدمج في ال DNA طبعا مهم
+
+360
+00:24:48,700 --> 00:24:52,640
+جدا نعرف على هذه العوامل اللي قسمها Intrinsic
+
+361
+00:24:52,860 --> 00:24:57,400
+وextrinsic factor أكثر انتشاراً الـextrinsic
+
+362
+00:24:57,400 --> 00:25:01,860
+factor هي الأكثر انتشارا من أشهر الفحوصات التي
+
+363
+00:25:01,860 --> 00:25:05,860
+يمكن أن تستخدم بتحديد الـDNA fragmentationهي عبارة
+
+364
+00:25:05,860 --> 00:25:09,400
+عن فحص بنسميه Tunnel فحص Tunnel هو عبارة عن
+
+365
+00:25:09,400 --> 00:25:12,800
+Microscopic Dediction للأبيبتوسس فحص Tunnel هو
+
+366
+00:25:12,800 --> 00:25:17,240
+عبارة عن Microscopic Dediction للأبيبتوسس شو ال
+
+367
+00:25:17,240 --> 00:25:21,320
+принцип الأساسي الخاص فيه؟ ببساطة جدا، this assay
+
+368
+00:25:21,320 --> 00:25:27,580
+is based on the labeling of 3'3-hydroxyl-M of the
+
+369
+00:25:27,580 --> 00:25:32,770
+fragmented DNA with fluorescenceDiet catalyzed by
+
+370
+00:25:32,770 --> 00:25:36,930
+terminal DTT يعني بمعنى آخر، لو أنا فيه عندي
+
+371
+00:25:36,930 --> 00:25:40,670
+الـDNA الخاص بالـSpermatozoa الموجودة في الهدف، لو
+
+372
+00:25:40,670 --> 00:25:46,410
+صار لها fragmentation، هيصير عندي Freeموجودة على
+
+373
+00:25:46,410 --> 00:25:50,770
+الـ 3 Prime الـ Free OH الموجودة على الـ 3 Prime
+
+374
+00:25:50,770 --> 00:25:57,390
+تعتبر كمكان مميز ومكان as mark indicator على وجود
+
+375
+00:25:57,390 --> 00:26:01,190
+الـ Fragmentation ففي صبغة ممكن ترتبط مع هذا
+
+376
+00:26:01,190 --> 00:26:06,870
+المكان و تعطيني fluorescent dye الـ DTTP مميز مع
+
+377
+00:26:06,870 --> 00:26:10,050
+الـ fluorescent probe نستطيع اتجاهه باستخدام
+
+378
+00:26:10,050 --> 00:26:13,910
+ميكروسكوب fluorescent أو فلو سايتوميترالوصول
+
+379
+00:26:13,910 --> 00:26:18,150
+للسيجنال الطبيعي سيكون مرتبط بقيمة الـ Strand
+
+380
+00:26:18,150 --> 00:26:23,930
+Breaks والتي ستتفكر كمية الـ sperm DNA باختصار
+
+381
+00:26:23,930 --> 00:26:28,850
+شديد الـ Tunnel هو عبارة عن تحس يستخدم لقياس مدى
+
+382
+00:26:28,850 --> 00:26:32,310
+الـ Apoptosis أو الـ DNA Fragmentation في الـ
+
+383
+00:26:32,310 --> 00:26:36,870
+spermatozoa DNA من خلال أن في مادة موجودة في هذا
+
+384
+00:26:36,870 --> 00:26:42,560
+الـ reagent لها قابلية للارتباط مع الـ OHالـ Free
+
+385
+00:26:42,560 --> 00:26:46,440
+الموجودة على الـ 3 Prime من أين أجت أن عند Double
+
+386
+00:26:46,440 --> 00:26:50,960
+Strand DNA صارها Fragmentation أدت إلى وجود Free
+
+387
+00:26:50,960 --> 00:26:55,280
+OH موجودة على الـ 3 Prime ترتبط بهذه المادة المادة
+
+388
+00:26:55,280 --> 00:27:02,000
+هذه مرتبطة بـ Fluorescent Pro إذا عرضت للـ UV أو
+
+389
+00:27:02,000 --> 00:27:06,220
+لـ Fluorescent أو لـ Fluorescent Microscope هشوفها
+
+390
+00:27:06,220 --> 00:27:10,320
+تحت الميكروسكوب فممكن أقرأها ببساطة جدا على هيئة
+
+391
+00:27:10,320 --> 00:27:15,640
+percentageفي علاقة ما بين عدد ال indicator اللتي
+
+392
+00:27:15,640 --> 00:27:19,320
+تظهر عدد ال flow اللتي تظهر عدد ال light ال
+
+393
+00:27:19,320 --> 00:27:21,920
+ignition light اللتي تظهر ال emission light اللتي
+
+394
+00:27:21,920 --> 00:27:28,860
+تظهر و نسبة ال apoptosis كل ما زاد .. كل ما زاد ال
+
+395
+00:27:28,860 --> 00:27:34,020
+signal معناه في عندي عدد كبير من ال DNA apoptosis
+
+396
+00:27:34,020 --> 00:27:38,550
+أو ال DNA fragmentationصورة بتوضح الكلمة ده هاي في
+
+397
+00:27:38,550 --> 00:27:42,550
+عندي spam double strand يعنيه صار في عندي break في
+
+398
+00:27:42,550 --> 00:27:46,310
+ال double strand أدت إلى تكوين OH3 على ال 3 prime
+
+399
+00:27:46,310 --> 00:27:52,050
+عملتلها mixing بال tunnel kit فلجيت أنه في عند ال
+
+400
+00:27:52,050 --> 00:27:57,010
+DTT انزايم ارتبط فيها ومربوط بال fluoro scan لو
+
+401
+00:27:57,010 --> 00:27:59,630
+عرضته ل flow cytometer أو fluorescent microscope
+
+402
+00:27:59,630 --> 00:28:03,150
+هتعطيني emission لونه green ال emissionأو light
+
+403
+00:28:03,150 --> 00:28:07,610
+لونه green light لونه green يتناسب تناسبان طرديا
+
+404
+00:28:07,610 --> 00:28:11,470
+مع عدد الحيوانات المنوية التي بها defect أو بها
+
+405
+00:28:11,470 --> 00:28:17,470
+apoptosis الصورة أفضل دالين هي عندي صورة ال
+
+406
+00:28:17,470 --> 00:28:24,130
+background black وفي عندي لونين لون pale green
+
+407
+00:28:24,130 --> 00:28:29,090
+فاتح أخضر فاتح و لون dark green ال dark green
+
+408
+00:28:29,090 --> 00:28:31,930
+معناه اتونال positiveماذا يعني الـ tone الـ
+
+409
+00:28:31,930 --> 00:28:35,170
+positive؟ معناه إنه في صار في عندي fragmentation
+
+410
+00:28:35,170 --> 00:28:40,070
+ارتبطت ال probe مع ال OH الـ3 الموجودة على الـ 3
+
+411
+00:28:40,070 --> 00:28:44,810
+prime معناه إذا عرضتها لفلورسانت مايكروسكوب أو
+
+412
+00:28:44,810 --> 00:28:49,570
+الفلورسكال هيعطيني signal light لونه green كل ما
+
+413
+00:28:49,570 --> 00:28:53,110
+زاد ال intensity لل green color معناه في عندي كمية
+
+414
+00:28:53,110 --> 00:28:56,610
+fragmentation أعلى أما ال pale color معناه ال tone
+
+415
+00:28:56,610 --> 00:28:59,740
+الـ negative يعني مافي عندي fragmentation هناما في
+
+416
+00:28:59,740 --> 00:29:04,200
+OH3 يرتبط فيها الـ probe هنا عشان كده بقوللي
+
+417
+00:29:04,200 --> 00:29:06,740
+Tunnel Assay for Detection of Spare DNA
+
+418
+00:29:06,740 --> 00:29:13,060
+Fragmentation Under Fluorescent Microscope الـ
+
+419
+00:29:13,060 --> 00:29:16,640
+Normal DNA هيديني الـ Light Green عشان كده بسميه
+
+420
+00:29:16,640 --> 00:29:19,920
+Tunnel Negative بينما الـ Damaged DNA أو الـ
+
+421
+00:29:19,920 --> 00:29:24,940
+Apoptosis Spare هيعطيني Bright أو Dark Green وهو
+
+422
+00:29:24,940 --> 00:29:29,740
+عبارة عن الـ Tunnel الـ Positiveعن الـ tunnel
+
+423
+00:29:29,740 --> 00:29:34,860
+positive طبعاً هذا هي عبارة عن الفكرة ما بين ال
+
+424
+00:29:34,860 --> 00:29:38,160
+tunnel positive وال tunnel ال negative الخاصة
+
+425
+00:29:38,160 --> 00:29:42,120
+بقياس ال fragmentation sperm يعني fragmentation أو
+
+426
+00:29:42,120 --> 00:29:50,660
+sperm apoptosis سنكتفي
+
+427
+00:29:50,660 --> 00:29:55,000
+بهذا القدر من المعلومات في هذه المحاضرة على أمل أن
+
+428
+00:29:55,000 --> 00:29:59,280
+نتقي في المحاضرة القادمة ان شاء اللهDom Tom في حفظ
+
+429
+00:29:59,280 --> 00:29:59,420
+الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/LftGtVx2Jyc_postprocess.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/LftGtVx2Jyc_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..b1a31a1a4343ddf0674350f90b00e5a3f7bec3d8
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/LftGtVx2Jyc_postprocess.srt
@@ -0,0 +1,2388 @@
+1
+00:00:00,930 --> 00:00:05,210
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,210 --> 00:00:11,650
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلبنا
+
+3
+00:00:11,650 --> 00:00:16,070
+الأكارم نرجو من الله الكريم أن تكونوا جميعا بخير
+
+4
+00:00:16,070 --> 00:00:21,810
+وبصحة جيدة اليوم سوف نستكمل ما تقطع من الشبط
+
+5
+00:00:21,810 --> 00:00:26,880
+الرابعحيث تحدثنا في المحاضرات السابقة عن القالية
+
+6
+00:00:26,880 --> 00:00:31,600
+والنظام المتبع من أجل تحفيز المبيض للسيدة التي
+
+7
+00:00:31,600 --> 00:00:35,780
+تخضع لعمليات التلقيح الصناعي أو الزراعة من أجل
+
+8
+00:00:35,780 --> 00:00:40,500
+الحصول على أكبر عدد من البويضات الناضجة وذات
+
+9
+00:00:40,500 --> 00:00:45,520
+الجودة العالية وقُسمت هذه الأنظمة المستخدمة إلى
+
+10
+00:00:45,520 --> 00:00:50,020
+Agonist Protocol وAntagonist Protocolالـ Agonist
+
+11
+00:00:50,020 --> 00:00:54,100
+Protocol على سبيل المثال قُسم إلى Ultra Short و
+
+12
+00:00:54,100 --> 00:00:59,300
+Short و Long والـ Antagonist Protocol قُسم إلى One
+
+13
+00:00:59,300 --> 00:01:04,000
+Dose أو Single Dose أو Multi Doseأدى بالنسبة إلى
+
+14
+00:01:04,000 --> 00:01:08,380
+ما تحدثنا عنه في المحاضرة السابقة ثم انتقلنا
+
+15
+00:01:08,380 --> 00:01:13,160
+للتحدث عن حالة مرضية تسمى Hyperovarian Stimulation
+
+16
+00:01:13,160 --> 00:01:17,700
+Syndrome والتي تحدث عند بعض السيدات بسبب الإفراط
+
+17
+00:01:17,700 --> 00:01:22,740
+في عملية إعطاء الأدوية التي تعمل على تحفيظ المبيض
+
+18
+00:01:22,740 --> 00:01:27,920
+مما يؤدي إلى إنتاج بويضات غير ناضجة أو الوصول إلى
+
+19
+00:01:27,920 --> 00:01:35,050
+فوليكل ناضق تحتوي علىfluid بدون أي mature oocyte
+
+20
+00:01:35,050 --> 00:01:40,270
+اليوم سوف نتكلم عن المرحلة الثانية من مراحل تحضير
+
+21
+00:01:40,270 --> 00:01:46,090
+السيدة فبعد إعطاء السيدة هرمون الـHCG لـHuman
+
+22
+00:01:46,090 --> 00:01:50,710
+Chronic Gynadotropin الذي يعمل عمل الـLH من أجل
+
+23
+00:01:50,710 --> 00:01:56,280
+عمل ovulationيجب أن نلتقي وننتقل إلى نقطة جديدة
+
+24
+00:01:56,280 --> 00:02:04,060
+اسمها or oocyte pick up بمعنى
+
+25
+00:02:04,060 --> 00:02:08,860
+آخر عملية الحصاد عملية ال harvest بعد ما تم تحفيز
+
+26
+00:02:08,860 --> 00:02:14,900
+المبيع و اتصل فولكل بعدد معين و بعدد مناسب إلى
+
+27
+00:02:14,900 --> 00:02:20,680
+ديامتر مناسب أكبر من أو يساوي 18 ملي مترمعناه إن
+
+28
+00:02:20,680 --> 00:02:25,560
+هذه الفوليكل تحتوي على بويضة ناضجة تكون صالحة
+
+29
+00:02:25,560 --> 00:02:30,220
+للطلقيح الصناعي إذا كانت متوقفة في الـ Metaphase 2
+
+30
+00:02:30,220 --> 00:02:35,300
+Metaphase التاني يعني الـ Metaphase الخاص بالقسام
+
+31
+00:02:35,300 --> 00:02:38,920
+الميوزي الثاني والذي يدل على هذا الأمر وجود الـ
+
+32
+00:02:38,920 --> 00:02:42,600
+Ferrous Polar Body ننتقل إلى مرحلة جديدة وهي مرحلة
+
+33
+00:02:42,600 --> 00:02:47,560
+الـ Collection أو الـ Oocyte Retrieval أو الـ Ovum
+
+34
+00:02:47,560 --> 00:02:53,180
+Pick Upبمعنى آخر إن كل follicle وصلت إلى الـ
+
+35
+00:02:53,180 --> 00:02:57,900
+maturation stage المفروض تحتوي على بويضة ناتجة
+
+36
+00:02:57,900 --> 00:03:02,780
+المفروض بعد إعطاء الكورونادوتروبين administration
+
+37
+00:03:02,780 --> 00:03:08,260
+نستطيع هذه الـ follicle أن تقوم بعملية ovulation
+
+38
+00:03:08,260 --> 00:03:12,520
+ليه بتضبط بعد الكورونادوتروبين؟ لأن هذا الهرمون
+
+39
+00:03:12,520 --> 00:03:18,280
+مسئول عن عمل الألأتش أو عمله يحاكي عمل الألأتشوهي
+
+40
+00:03:18,280 --> 00:03:23,000
+عبارة عن عملية الـ ovulation and oocyte pickup is
+
+41
+00:03:23,000 --> 00:03:27,460
+performed approximately 36 hours later by
+
+42
+00:03:27,460 --> 00:03:31,940
+ultrasound transvaginal aspiration بمعنى آخر إن
+
+43
+00:03:31,940 --> 00:03:37,680
+عملية جمع البويضات تحدث بعد 36 ساعة من إعطاء إبرة
+
+44
+00:03:37,680 --> 00:03:42,000
+التفجير اللي بنسميها بالوضع العام بإبرة التفجير أو
+
+45
+00:03:42,000 --> 00:03:46,500
+sheregon يعني إبرة التفجير إبرة الشيرجون وهي عبارة
+
+46
+00:03:46,500 --> 00:03:52,320
+عنأبرة تحتوي على كورونات جونادوتروبين هورمون طبعاً
+
+47
+00:03:52,320 --> 00:03:55,820
+عملية بتصير عملية ال collection عن طريق ال
+
+48
+00:03:55,820 --> 00:04:00,080
+aspiration باستخدام needle معينة بجوج معينة تدخل
+
+49
+00:04:00,080 --> 00:04:03,500
+من خلال ما يُعرف باسم ال Transvaginal aspiration
+
+50
+00:04:03,500 --> 00:04:09,240
+هذه العملية ككلفي لحظة عمل الـ Oocyte Collection
+
+51
+00:04:09,240 --> 00:04:12,980
+لازم نعمل Clearing للفاجينة بالـ Normal Saline
+
+52
+00:04:12,980 --> 00:04:18,440
+بدون استخدام أي مطهر على سبيل المثال الـ Betadine
+
+53
+00:04:18,440 --> 00:04:24,040
+لا يمكن ولا ينصح باستخدامه كنوع من أنواع المطهرات
+
+54
+00:04:24,040 --> 00:04:28,900
+قبل عملية الـ Egg Collectionلأنه very toxic وممكن
+
+55
+00:04:28,900 --> 00:04:33,920
+يؤثر على ال egg بشكل سلبي وبشكل غير مرغوب فيه
+
+56
+00:04:33,920 --> 00:04:37,500
+عملية جمع البويضات تسمى ال oocyte pick up أو ال
+
+57
+00:04:37,500 --> 00:04:41,820
+oocyte harvest أو harvest the harvesting is
+
+58
+00:04:41,820 --> 00:04:45,660
+carried out using the aspiration unit composed of
+
+59
+00:04:45,660 --> 00:04:50,260
+vacuum pumpA collection tube connected to 70 gauge
+
+60
+00:04:50,260 --> 00:04:53,840
+needle and collection test tube يعني الوحدة
+
+61
+00:04:53,840 --> 00:04:57,720
+المسؤولة عن عملية جمع البويضات تتكون من تلت مكونات
+
+62
+00:04:57,720 --> 00:05:02,020
+أساسية المكون الأول هو ال vacuum pump مضخة تعتمد
+
+63
+00:05:02,020 --> 00:05:08,590
+علىالـ suction سحب الأواء الشغلة التانية و سحب الـ
+
+64
+00:05:08,590 --> 00:05:11,710
+fluid الشغلة التانية الـ collection tube متصلة
+
+65
+00:05:11,710 --> 00:05:16,910
+بنيدل الجوج تبعها 17 بالإضافة إلى collection test
+
+66
+00:05:16,910 --> 00:05:20,590
+tube وهي الـ test tube التي تجمع بها البوايضات هذه
+
+67
+00:05:20,590 --> 00:05:25,750
+عبارة عن الـ oocyte collection unit تلت مكونات
+
+68
+00:05:25,750 --> 00:05:30,910
+vacuum pump collection tube متصلة بالجوج نيدل 17 و
+
+69
+00:05:30,910 --> 00:05:35,160
+collection test tubeالـ fluid الموجود داخل الـ
+
+70
+00:05:35,160 --> 00:05:39,100
+follicle يجب أن يُسحب كله ويجب أن يُسحب من كل
+
+71
+00:05:39,100 --> 00:05:43,400
+follicle وصلت إلى 18 mm على الأقل سواء كان في الـ
+
+72
+00:05:43,400 --> 00:05:46,960
+over اليمين أو في ال over اليسار فبالتالي أنا أسحب
+
+73
+00:05:46,960 --> 00:05:50,720
+كل fluid الموجود معناه أنا بسحب ال fluid مع ال
+
+74
+00:05:50,720 --> 00:05:54,280
+oocyte سواء كانت mature أو immature لأن ال
+
+75
+00:05:54,280 --> 00:05:59,400
+immature في خارج جسم الإنسان لها استخدامات شتة بعد
+
+76
+00:05:59,400 --> 00:06:03,310
+كده ببدأأعمل examination للـ fluid اللي جمع في ال
+
+77
+00:06:03,310 --> 00:06:07,790
+test tube علشان أشوف كداش عدد البوايدات الموجودة و
+
+78
+00:06:07,790 --> 00:06:10,710
+أبدأ أعمل collection لهذه البوايدات و أنقلها من
+
+79
+00:06:10,710 --> 00:06:16,150
+هذا ال fluid إلى a new media اللي اسمها maturation
+
+80
+00:06:16,150 --> 00:06:23,800
+media أو IVF mediaDuring the collection يجب أن
+
+81
+00:06:23,800 --> 00:06:28,740
+يستخدم ضغط يقدر على أقصى حد مائة وعشرين ميلي متر
+
+82
+00:06:28,740 --> 00:06:34,080
+ذئبقي هذا الضغط الموصفي خلال عملية الجمع وإلا
+
+83
+00:06:34,080 --> 00:06:37,670
+زيادة الضغط بيعمل rupture في ال follicleوهذا شيء
+
+84
+00:06:37,670 --> 00:06:41,950
+غير مطلوب to avoid the risk of damage of oocyte
+
+85
+00:06:41,950 --> 00:06:45,990
+such as stripping the cumulus cell or the zona
+
+86
+00:06:45,990 --> 00:06:50,910
+plucida بمعنى آخر إنه مهم جدا أستخدم ضغط يقدر
+
+87
+00:06:50,910 --> 00:06:56,400
+بـ120 ميلي متر ذئبقي خلال عملية الجمعما أزيد هذا
+
+88
+00:06:56,400 --> 00:07:00,280
+الضغط لأن زيادته ممكن تؤثر على ال oocyte بشكل سلبي
+
+89
+00:07:00,280 --> 00:07:04,660
+وتدمرها أو تدمر ال cumulus الموجودة حوالي ال
+
+90
+00:07:04,660 --> 00:07:07,700
+oocyte أو تدمر الزيونابليوسيدا ودمرت
+
+91
+00:07:07,700 --> 00:07:10,440
+الزيونابليوسيدا يعني أنا فقط ال cytoplasm والمادة
+
+92
+00:07:10,440 --> 00:07:14,980
+النووية once the oocyte are collected they are
+
+93
+00:07:14,980 --> 00:07:19,320
+placed or put in culture plate with neutron media
+
+94
+00:07:19,320 --> 00:07:24,060
+and then placed into incubator بمجرد ما أحصل على
+
+95
+00:07:24,060 --> 00:07:28,050
+ال oocyteالـ fluid اللي جمعته من الـ follicle و
+
+96
+00:07:28,050 --> 00:07:31,130
+ابتدأ أعمل examination تحت ال inverted microscope
+
+97
+00:07:31,130 --> 00:07:34,910
+و أجمع البويضات هذه البويضات باخدها ب sterile
+
+98
+00:07:34,910 --> 00:07:38,830
+dropper و بنجلها على طبق يحتوي على قطرات من ال
+
+99
+00:07:38,830 --> 00:07:43,630
+media المغذية و بنقل هذا الطبق و بوضعه في ال
+
+100
+00:07:43,630 --> 00:07:49,210
+incubator بقولي ببساطة جدا هذه العملية كلها تحدث
+
+101
+00:07:49,210 --> 00:07:54,100
+عملية ال oocyte collection تحت تخدير موضعيأو تخدير
+
+102
+00:07:54,100 --> 00:07:58,080
+كلي ولكن خفيف لفترة زمانية قصيرة الفترة الزمانية
+
+103
+00:07:58,080 --> 00:08:00,840
+المفروض تاخدها العملية كلها عملية ال egg
+
+104
+00:08:00,840 --> 00:08:04,340
+collection و ال fluid aspiration من 10 إلى 15
+
+105
+00:08:04,340 --> 00:08:09,020
+دقيقة و الطبيب الشاطر ما بتطلق blood في ال fluid
+
+106
+00:08:09,020 --> 00:08:14,640
+المسحوب من ال follicle Therefore, during a system
+
+107
+00:08:14,640 --> 00:08:17,080
+reproductive technology procedure, cumulus cells
+
+108
+00:08:17,080 --> 00:08:19,440
+surrounding the oocyte should be removed to
+
+109
+00:08:19,440 --> 00:08:23,120
+improve oocyte evaluation and manipulationهنعرف
+
+110
+00:08:23,120 --> 00:08:26,500
+إيش يعني cumulus cell واتكلمنا عنها cumulus cell
+
+111
+00:08:26,500 --> 00:08:29,900
+فيما سبق إنه في خلايا خفيفة موجودة حول ال oocyte
+
+112
+00:08:29,900 --> 00:08:33,200
+تسمى cumulus cell هذه ال cumulus cell لازم أخفف
+
+113
+00:08:33,200 --> 00:08:37,120
+عددها بشكل كبير جدا أو أزينها علشان يسهل عملية
+
+114
+00:08:37,120 --> 00:08:42,380
+evaluation لل oocyte وأحدد هل هي mature ولا
+
+115
+00:08:42,380 --> 00:08:45,460
+immature ويسهل عملية ال manipulation وما المقصود
+
+116
+00:08:45,460 --> 00:08:50,060
+فيها ال injection مهم جداأعرّ الخلية، أخفف عدد الـ
+
+117
+00:08:50,060 --> 00:08:52,920
+Cumulus Cell اللي حوالها، أزيل الـ Cumulus Cell
+
+118
+00:08:52,920 --> 00:08:59,500
+اللي حوالها بعض الأحيان بكون عندى بويضات أو بكون
+
+119
+00:08:59,500 --> 00:09:03,800
+عندى Full Hill وصلت للـ18 مليمتر ولكن البويضات لم
+
+120
+00:09:03,800 --> 00:09:07,450
+تصل إلى درجة النضوجةفبطّر في هذه الحلقة أعملها
+
+121
+00:09:07,450 --> 00:09:11,710
+maturation outside in vitro maturation تحت مصطلح
+
+122
+00:09:11,710 --> 00:09:15,670
+oocyte maturation في ال clinical IVF laboratories
+
+123
+00:09:15,670 --> 00:09:21,090
+التكنولوجيست اللي بيشتغلوا في هذا المجال بيميلوا
+
+124
+00:09:21,090 --> 00:09:25,890
+إلى استغلال البويضات الغير ناضجة وانضاجها في
+
+125
+00:09:25,890 --> 00:09:31,470
+المختبر ثم استخدامها في عملية الحقد من أجل زيادة
+
+126
+00:09:31,470 --> 00:09:36,740
+عدد البويضات المحقونة مما يؤدي لزيادة معدلالحقن أو
+
+127
+00:09:36,740 --> 00:09:40,200
+معدل ال fertilization وخدوا بالك بعض البويضات اللي
+
+128
+00:09:40,200 --> 00:09:44,060
+بالشكل هذا بتنجح و بتعطيني embryo و البعض لا ينجح
+
+129
+00:09:44,060 --> 00:09:47,780
+ولا يعطي embryo في بعض البويضات في بتكون في مرحلة
+
+130
+00:09:47,780 --> 00:09:54,000
+ال GV وهي التي تسمى germinal vesicle وفي مرحلة ال
+
+131
+00:09:54,000 --> 00:09:59,600
+M1 وهي القسم الميوز الأولوفي الـ M2 القسم الميوزي
+
+132
+00:09:59,600 --> 00:10:05,680
+التاني فبالتالي myotic maturation actually is a
+
+133
+00:10:05,680 --> 00:10:08,740
+continuous process and some oocyte aspirated from
+
+134
+00:10:08,740 --> 00:10:14,000
+follicle of various size would be expected to be
+
+135
+00:10:14,000 --> 00:10:16,560
+intermediate stage of maturation يعني في بعض
+
+136
+00:10:16,560 --> 00:10:20,060
+الأحيان بيصير في عندي بعض ال follicle تحتوي على
+
+137
+00:10:20,060 --> 00:10:26,420
+بويضات أنا بسحب هذه ال fluid وبما فيها منبوايضات
+
+138
+00:10:26,420 --> 00:10:30,700
+ولكن بلاج البوايضات غير ناضجة أو وكفت في أحد ال
+
+139
+00:10:30,700 --> 00:10:34,560
+stage الذي يُعتبر intermediate stage خلال عملية ال
+
+140
+00:10:34,560 --> 00:10:39,640
+maturation من أشهر هذه البوايضات زي ما حكينا هي ال
+
+141
+00:10:39,640 --> 00:10:43,840
+GV من أشهر هذه البوايضات التي تُعتبر إما pure
+
+142
+00:10:43,840 --> 00:10:48,240
+oocyte هي ال GV وهي ال germinal vesicle و ال
+
+143
+00:10:48,240 --> 00:10:53,120
+metaphase I إذن أنا عندي أربع .. تلت أقسام
+
+144
+00:10:53,120 --> 00:11:00,080
+للبوايضة ممكن أحصل عليهاإما GV أو M1 أو M2 M2
+
+145
+00:11:00,080 --> 00:11:05,400
+معناه إن البويضة وقفت في انقسام الميوز الثاني في
+
+146
+00:11:05,400 --> 00:11:10,440
+الـ Stage Metaphyse فهي صالحة للحقن الـ GV الـ
+
+147
+00:11:10,440 --> 00:11:14,660
+Germinal Vesicle و الـ M1 يعني انقسام الميوز الأول
+
+148
+00:11:14,660 --> 00:11:18,100
+في الـ Metaphyse الأول أو انقسام الميوز الأول
+
+149
+00:11:18,100 --> 00:11:23,280
+معناه هذه البويضات إما pure oocyte تكون غير صالحة
+
+150
+00:11:23,280 --> 00:11:28,810
+للحقن إلا بعضبعد الإنضاج ومش كلهم بيصلوا لل level
+
+151
+00:11:28,810 --> 00:11:32,210
+الخاص بال maturation break down of germinal
+
+152
+00:11:32,210 --> 00:11:39,050
+vesicle indicates the continuance of meiosis and
+
+153
+00:11:39,050 --> 00:11:42,590
+ejaculate of the first polar body indicates
+
+154
+00:11:42,590 --> 00:11:45,250
+complete the first meiotic division in human
+
+155
+00:11:45,250 --> 00:11:49,130
+oocyte عشان أقول والله الخلية أو الويضة التي
+
+156
+00:11:49,130 --> 00:11:53,480
+سُحِبت وهي في مرحلة ال GV ال germinal vesicleلازم
+
+157
+00:11:53,480 --> 00:11:58,060
+أوضعها في ظروف تشبه الظروف الموجودة داخل الـ Opera
+
+158
+00:11:58,060 --> 00:12:01,480
+الخاصة بالسيدة يعني في ظروف شبه طبيعية في media
+
+159
+00:12:01,480 --> 00:12:06,280
+تحاكي الظرفة التي تعيش فيها البوايدة عشان أسمح لها
+
+160
+00:12:06,280 --> 00:12:11,960
+بالنضوج والدليل على نضوجها أو تحويلها من GV إلى
+
+161
+00:12:11,960 --> 00:12:19,240
+مثلا M2 تكون عند إذن صالح للحقل أنه يزيد حجمها
+
+162
+00:12:19,730 --> 00:12:24,290
+وتقضف ال first polar body الخاص بها للخارج فبتطيني
+
+163
+00:12:24,290 --> 00:12:30,210
+خلية أو بويضة اسمها بويضة ناضجة في مرحلة ال M2 عند
+
+164
+00:12:30,210 --> 00:12:34,110
+هذا اللحظة أو عند تلك اللحظة تكون صالحة للإخصام
+
+165
+00:12:34,110 --> 00:12:40,630
+اذا تلت حالات البويضة تلخيص الحدث GV M1 M2 هذه
+
+166
+00:12:40,630 --> 00:12:44,390
+حالات البويضة التي يمكن أنراها ال M2 تكون هي
+
+167
+00:12:44,390 --> 00:12:49,030
+الوحيدة الصالحة لعملية الإخصادالـ GV هي عبارة عن
+
+168
+00:12:49,030 --> 00:12:54,150
+خلية غير ناضجة والـ M1 خلية غير ناضجة أيضًا يمكن
+
+169
+00:12:54,150 --> 00:12:59,350
+أن تنضج في المختبر صورة توضح الكلام اللي احنا
+
+170
+00:12:59,350 --> 00:13:05,170
+حكيناه عن طبيعة انقسام البويضة هي في عندي الـ GV
+
+171
+00:13:05,170 --> 00:13:11,190
+الخاص بالبويضة على سبيل المثال هذه GV وهي عبارة عن
+
+172
+00:13:11,190 --> 00:13:15,970
+German Visicleوهي عند ال M1 وهي عبارة عن البويضة
+
+173
+00:13:15,970 --> 00:13:18,770
+اللتي وقفت في أحد الستجل خاصة بالانقسام الميوزي
+
+174
+00:13:18,770 --> 00:13:25,590
+الأول وهي M2 وهي عبارة عن البويضة البويضة دخلت
+
+175
+00:13:25,590 --> 00:13:32,570
+وأنهت الانقسام الميوزي الأول واتوقفت في الانقسام
+
+176
+00:13:32,570 --> 00:13:37,110
+الميوزي التاني في مرحلة ال meta phase مما أدى إلى
+
+177
+00:13:37,110 --> 00:13:43,730
+ظهور ال fairest polar bodyبعد ال maturation و ال
+
+178
+00:13:43,730 --> 00:13:48,450
+fertilization يظهر ال second polar body لأنه حكينا
+
+179
+00:13:48,450 --> 00:13:52,530
+أن ال first polar body هو أول indication على أن
+
+180
+00:13:52,530 --> 00:13:57,150
+البويضة أنهت الانقسام الميوز الأول و أنهت جزء كبير
+
+181
+00:13:57,150 --> 00:14:01,470
+من انقسام الميوز التاني و توقفت في ال stage الاسم
+
+182
+00:14:01,470 --> 00:14:06,850
+ميتا فيز 2 يعني الميتا فيز التاني من انقسام التاني
+
+183
+00:14:06,850 --> 00:14:10,440
+او الميتا فيز الخاص بالانقسام الميوز التانيأما
+
+184
+00:14:10,440 --> 00:14:13,160
+بالنسبة إلى الـ two polar body أو الـ second polar
+
+185
+00:14:13,160 --> 00:14:19,040
+body لا يظهر إلا بعد عملية ونجاح عملية ال
+
+186
+00:14:19,040 --> 00:14:23,800
+fertilization تلقيح البويضة من خلال وجود ال spirit
+
+187
+00:14:23,800 --> 00:14:31,060
+هذه عبارة عن مراحل البويضة بشكل الكامل طيب the
+
+188
+00:14:31,060 --> 00:14:34,520
+immature oocyte are incubated in the original
+
+189
+00:14:34,870 --> 00:14:38,570
+Culture Media or Original Tissue Culture Dish
+
+190
+00:14:38,570 --> 00:14:42,570
+بتكون من واحد أو يحتوي على واحد مليمتر من الـ
+
+191
+00:14:42,570 --> 00:14:45,670
+Oocyte Maturation Media يعني الميديا المستخدمة
+
+192
+00:14:45,670 --> 00:14:50,370
+لتطوير ونضوج الـ Oocyte حيث تحتوي هذه الميديا على
+
+193
+00:14:50,370 --> 00:14:55,630
+75 ملل International Unit لكل مليلتر من الـ FSH
+
+194
+00:14:55,630 --> 00:15:00,530
+بالإضافة إلى 75 من الـ LH وموجودة في إنكبياتور 37
+
+195
+00:15:00,530 --> 00:15:05,730
+درجة مئوية يعني كل هذه الميدياهي مواد مغذية ودرجة
+
+196
+00:15:05,730 --> 00:15:09,570
+حرارة مناسبة بالإضافة إلى هرمونات الأفاساتش
+
+197
+00:15:09,570 --> 00:15:14,910
+والألاتش المستخدمان في إنضاج البوايدة طبعا بوضعوها
+
+198
+00:15:14,910 --> 00:15:20,630
+في إنكبياتور على 37 درجة مئوية في وجود 5% carbon
+
+199
+00:15:20,630 --> 00:15:27,050
+dioxide و95% air with high humidity ويجب أن تكون
+
+200
+00:15:27,050 --> 00:15:31,110
+في نسبة عالية من الرطوبة طبعا يفضل إنها تحضن
+
+201
+00:15:31,110 --> 00:15:35,570
+البوايدة الغير نادجة لكي تنضجفي وجود انكبياتور فيه
+
+202
+00:15:35,570 --> 00:15:39,410
+triple gas نيتروجين كاربون دايفسايد اكسيجين
+
+203
+00:15:39,410 --> 00:15:45,570
+النيتروجين يوصف 90% الثريفستر كاربون 5% والأكسيجن
+
+204
+00:15:45,570 --> 00:15:50,870
+5% و ال humidity الرطوبة 100% عشان كده لإما بيكون
+
+205
+00:15:50,870 --> 00:15:55,190
+في عندي normal saline bottle معلقة في الانكبياتور
+
+206
+00:15:55,190 --> 00:15:59,250
+من الخارج موصلة بأنبوب لداخل الانكبياتور عشان توفر
+
+207
+00:15:59,800 --> 00:16:03,820
+الرطوبة المناسبة أو بيضعوا يعني زي حاوية بسيطة
+
+208
+00:16:03,820 --> 00:16:06,980
+فيها ديستل ووتر أو ultra pure water داخل ال
+
+209
+00:16:06,980 --> 00:16:10,900
+incubator علشان في درجة حرارة 37 بتتبخر الماء
+
+210
+00:16:10,900 --> 00:16:15,880
+فبتكونلي كمية مناسبة ودرجة مناسبة من الرطوبة التي
+
+211
+00:16:15,880 --> 00:16:20,820
+تبقي البوايدة في حالة جيدة جدا ال oocyte
+
+212
+00:16:20,820 --> 00:16:26,220
+maturation media should be preparedبنسبة .. طبعا
+
+213
+00:16:26,220 --> 00:16:30,740
+ال media التي تستخدم لإنضاج ال oocyte يجب أن تحضر
+
+214
+00:16:30,740 --> 00:16:35,360
+قبل ساعتين من وضع البويضة الغير نادجة ويفضل أن
+
+215
+00:16:35,360 --> 00:16:40,040
+تحضر قبل بيوم يعني بنحضرها و بنحط لها drops أو
+
+216
+00:16:40,040 --> 00:16:42,480
+بنحط ال media في ال petri dish و ال petri dish
+
+217
+00:16:42,480 --> 00:16:46,280
+بندخله داخل ال incubator اللي فيه ال triple gas و
+
+218
+00:16:46,280 --> 00:16:52,040
+37 درجة موية علشان يصير في عندي balance و عملية
+
+219
+00:16:52,040 --> 00:16:57,450
+اتزان في ال pHمهم جدا علشان ما تروح البويضة على
+
+220
+00:16:57,450 --> 00:17:02,010
+أتموسفير أو تروح على ميديا مختلفة اختلاف كل فبيصير
+
+221
+00:17:02,010 --> 00:17:05,830
+فيها shock وممكن يصير failure فتحضير ال media جابل
+
+222
+00:17:05,830 --> 00:17:09,050
+بساعتين من خلال وضعها في الطبق ويدخل الطبق لل
+
+223
+00:17:09,050 --> 00:17:13,630
+incubator بيخل فيه اتزان واستقبال وتكييف للميديا
+
+224
+00:17:13,630 --> 00:17:18,870
+مع الظرف المحيط بها ال oocyte will be arrivedto
+
+225
+00:17:18,870 --> 00:17:22,550
+the metaphase of the second meiotic division stage
+
+226
+00:17:22,550 --> 00:17:29,610
+on the day of collection are stripping
+
+227
+00:17:29,610 --> 00:17:33,230
+and fertilized يعني بمعنى أخر بيسميها الـ
+
+228
+00:17:33,230 --> 00:17:37,330
+denudation بمعنى أخر أن البوايضة اللي كانت في حالة
+
+229
+00:17:37,330 --> 00:17:42,350
+ال maturation و ساحبناها و هي mature لازم في يوم
+
+230
+00:17:42,350 --> 00:17:47,240
+السحب تتعرض لحالتينولا خطواتين الخطوة الأولى الـ
+
+231
+00:17:47,240 --> 00:17:50,980
+Denodation أو الـ Stripping بسموها التعرية وإزالة
+
+232
+00:17:50,980 --> 00:17:54,540
+الكيومال السل و النقطة التانية ال fertilization
+
+233
+00:17:54,540 --> 00:17:59,920
+طبعا together with any in vitro matured oocyte
+
+234
+00:17:59,920 --> 00:18:04,240
+while immature oocyte are collected in IVM media
+
+235
+00:18:04,240 --> 00:18:10,640
+for 24 to 48 hours يعني أي بويضة ناضجة وكانت ناضجة
+
+236
+00:18:10,640 --> 00:18:14,440
+في يوم السحب يجب أن يحدث لها denodation أو
+
+237
+00:18:14,440 --> 00:18:17,760
+strippingو fertilization في نفس اليوم مش أجيله من
+
+238
+00:18:17,760 --> 00:18:21,400
+أي يوم تاني لأ في نفس اليوم السحب بيصير ال
+
+239
+00:18:21,400 --> 00:18:25,920
+injection أما بالنسبة للبوايضة الغير نادجة لازم
+
+240
+00:18:25,920 --> 00:18:30,700
+أوضعها في ال IVM media و يعني ما يطلق عليها in
+
+241
+00:18:30,700 --> 00:18:36,430
+vitro maturation mediaلمدة 24 ساعة على الأقل وعلى
+
+242
+00:18:36,430 --> 00:18:42,150
+الأكثر 48 ساعة لكي يسمح أو نسمح لهذه البويضة
+
+243
+00:18:42,150 --> 00:18:46,730
+بالنضوج الـ Follicle is the basic functional unit
+
+244
+00:18:46,730 --> 00:18:51,050
+of mammalian ovary which each follicle contained a
+
+245
+00:18:51,050 --> 00:18:53,370
+single oocyte surrounded by inner layer of
+
+246
+00:18:53,370 --> 00:18:56,170
+granulosa cell and outer layer of fecal cell
+
+247
+00:18:56,170 --> 00:19:00,650
+الفوليكل هي الوحدة الأساسية التي تحتوي على البويضة
+
+248
+00:19:00,650 --> 00:19:09,360
+الناضجة أو غير ناضجةفبالتالي هذه البويضة و
+
+249
+00:19:09,360 --> 00:19:14,330
+كل بويضة ناضجةتكون محاطة بطبقة خفيفة و رقيقة جدا
+
+250
+00:19:14,330 --> 00:19:17,210
+من الـ granulosa cell بالاضافة .. طبعا هذه طبقة
+
+251
+00:19:17,210 --> 00:19:21,270
+داخلية أو طبقات في بعض الأحيان بتكون داخلية من الـ
+
+252
+00:19:21,270 --> 00:19:25,270
+granulosa cell بالاضافة إلى طبقة أو طبقات متعددة
+
+253
+00:19:25,270 --> 00:19:29,010
+من الخارج تسمى fecal cell وحنشوفها كمان شوية
+
+254
+00:19:29,010 --> 00:19:35,030
+بالصورة يعني في المركز بويضة حواليها طبقات متعددة
+
+255
+00:19:35,030 --> 00:19:39,740
+من الخلايا تسمى الـ granulosa cellومن الخارج طبقات
+
+256
+00:19:39,740 --> 00:19:43,120
+متعددة من الـ fecal cell الـ granulosa cell بتلعب
+
+257
+00:19:43,120 --> 00:19:47,280
+دور مهم جدا بتعمل زي ال nursing يعني زي كأنها
+
+258
+00:19:47,280 --> 00:19:53,000
+بتعمل خادمة أو ممرضة أو يعني حاجة بتسهر على راحة
+
+259
+00:19:53,000 --> 00:19:57,520
+البوادة توفر الأمور اللازمة للبوادة nurse أو
+
+260
+00:19:57,520 --> 00:20:01,540
+nursing the oocyte and differentiated and
+
+261
+00:20:01,540 --> 00:20:06,530
+proliferation in response to gonadotropinالتي مهمة
+
+262
+00:20:06,530 --> 00:20:12,310
+لتطبيق و تضميد و إنعاش البويضة لعنى الـ Granulosa
+
+263
+00:20:12,310 --> 00:20:17,230
+cell بالمجمل تلعب دور مهم جدا في تطبيق و تضميد و
+
+264
+00:20:17,230 --> 00:20:22,550
+إنعاش البويضة كما أنها تلعب دور مهم جدا في تميز و
+
+265
+00:20:22,550 --> 00:20:27,750
+نمو البويضة كما أنها تلعب مهم جدا في استجابة و
+
+266
+00:20:27,750 --> 00:20:31,750
+زيادة استجابة البويضة لل-gonadotropin هرمون الذي
+
+267
+00:20:31,750 --> 00:20:37,630
+يُعطى فبالتاليفهي تلعب دورة حاسمة ودورة مهمة في
+
+268
+00:20:37,630 --> 00:20:42,430
+نجاح نمو البوايضة ونجاح عملية ال ovulation هذا
+
+269
+00:20:42,430 --> 00:20:46,230
+بالنسبة إلى ال granulosa cell بدونها البوايضة لن
+
+270
+00:20:46,230 --> 00:20:51,430
+تنمو بدونها البوايضة لن تنضج بدونها ال ovulation
+
+271
+00:20:51,430 --> 00:20:55,970
+لن يحدث لأن حكينا إنها بتلعب دور كبير وسارفنا إيش
+
+272
+00:20:55,970 --> 00:20:58,730
+الدور اللي بتلعبه من أهمها ال response for
+
+273
+00:20:58,730 --> 00:21:02,250
+gonadotropin على سبيل المثالThere are bi
+
+274
+00:21:02,250 --> 00:21:05,830
+-directional communication between the oocyte and
+
+275
+00:21:05,830 --> 00:21:09,290
+the surrounding somatic cell من خلال الـ Gap
+
+276
+00:21:09,290 --> 00:21:13,430
+Injection and Paracrine Signal طبعا الـ Somatic
+
+277
+00:21:13,430 --> 00:21:17,730
+Cell أو الـ Oocyte خليني أسميها بالمجمل ما بتكون
+
+278
+00:21:17,730 --> 00:21:22,750
+في معزل عن الخلايا الأخرى أو البيئة المحيطة فيها
+
+279
+00:21:22,750 --> 00:21:27,610
+لأ في عندي connection تؤثر وتتأثر تتأثر بالبيئة
+
+280
+00:21:27,610 --> 00:21:31,610
+المحيطة وتؤثر على البيئة المحيطةمن خلال junction
+
+281
+00:21:31,610 --> 00:21:34,270
+gap موجودة ما بينها وما بين الـ somatic cell
+
+282
+00:21:34,270 --> 00:21:38,710
+المحيطة بها ومن خلال ما يُعرف اسم الـ Paracrine
+
+283
+00:21:38,710 --> 00:21:42,650
+Signal ويعرفين الناس اللي أخدت Indocrine في حسمة
+
+284
+00:21:42,650 --> 00:21:48,690
+Autocrine في Paracrine وفي أنواع مختلفة من ال
+
+285
+00:21:48,690 --> 00:21:52,230
+signal من Indocrine و Paracrine و Autocrine هذه
+
+286
+00:21:52,230 --> 00:21:57,370
+أنواع مختلفة من ال signal بتفرز بالفعل الخلايا
+
+287
+00:21:57,370 --> 00:22:02,090
+الموجودة طبعاهذه العملية بتسهل بشكل كبير جدا نمو
+
+288
+00:22:02,090 --> 00:22:05,890
+البوايضة و تطور البوايضة الموجودة داخل الـ
+
+289
+00:22:05,890 --> 00:22:08,850
+follicle مما يؤدي إلى نجاح عملية الـ
+
+290
+00:22:08,850 --> 00:22:14,690
+folliculogenesis عملية تطور البوايضة نجد المرحلة
+
+291
+00:22:14,690 --> 00:22:18,230
+الأولى التي تحدث و العملية الأولى التي تحدث بعد
+
+292
+00:22:18,230 --> 00:22:21,530
+عملية الـ collection و هي ما يُعرف اسم oocyte
+
+293
+00:22:21,530 --> 00:22:25,510
+denodation أو denoding في الغالب بيسموها stripping
+
+294
+00:22:25,510 --> 00:22:30,030
+أو denodation يعني التعرية أو الإزالةطبعاً لما
+
+295
+00:22:30,030 --> 00:22:34,550
+أقول oocyte denoding تعني إزالة الـ somatic cell
+
+296
+00:22:34,550 --> 00:22:38,890
+المحيطة بالـ oocyte لأن أنا ما بدي أثناء عملية ال
+
+297
+00:22:38,890 --> 00:22:43,650
+injection أدخل somatic cell داخل الـ oocyte خلال
+
+298
+00:22:43,650 --> 00:22:46,510
+عملية ال injection أو جزء من المادة الوراثية
+
+299
+00:22:46,510 --> 00:22:49,770
+الخاصة بالـ somatic cell تدخل مع الإبرة خلال عملية
+
+300
+00:22:49,770 --> 00:22:52,830
+ال injection فبدي أزيل أغلب الـ somatic cell
+
+301
+00:22:52,830 --> 00:22:56,670
+المحيطة بالـ oocyte علشان أعمل injection بشكل صحيح
+
+302
+00:22:57,000 --> 00:23:00,980
+و مضمون 100% The removal of cumulus cell become
+
+303
+00:23:00,980 --> 00:23:04,860
+critical step, very necessary step, very important
+
+304
+00:23:04,860 --> 00:23:09,940
+step before fertilization since it allow an
+
+305
+00:23:09,940 --> 00:23:14,940
+evaluation of oocyte nuclear maturity and easily
+
+306
+00:23:14,940 --> 00:23:19,150
+handling of the oocyteDuring manipulation عملية
+
+307
+00:23:19,150 --> 00:23:22,790
+الإزالة عملية الـ stripping تسمح لأنا ك تكنولوجيست
+
+308
+00:23:22,790 --> 00:23:27,370
+أقيم ال Oocyte بشكل صحيح هل هي M1 ولا M2 ولا GV
+
+309
+00:23:27,370 --> 00:23:32,170
+أيضا بسهل عملية ال injection أن أعمل injection في
+
+310
+00:23:32,170 --> 00:23:35,510
+منطقة بعيدة عن ال polar body أعمل injection في
+
+311
+00:23:35,510 --> 00:23:39,130
+منطقةتحتوي على كمية قليلة جدا من الـ somatic cell
+
+312
+00:23:39,130 --> 00:23:44,270
+The cumulus and corona cell are removed before any
+
+313
+00:23:44,270 --> 00:23:49,670
+step of micromanipulation procedure by using two
+
+314
+00:23:49,670 --> 00:23:54,190
+method enzymatic method و mechanical treatment أنا
+
+315
+00:23:54,190 --> 00:23:57,770
+ممكن أعمل denodation أو stripping قبل ما أعمل أي
+
+316
+00:23:57,770 --> 00:24:01,400
+خطوة من خطوات ال injectionإما بستخدم إنزيم، هنعرف
+
+317
+00:24:01,400 --> 00:24:06,100
+إيش هو الإنزيم وكيف بستخدمه أو بستخدم طريقة يدوية،
+
+318
+00:24:06,100 --> 00:24:10,320
+ميكانيكية من أشهر الإنزيمات اللي تستخدم هو إنزيم
+
+319
+00:24:10,320 --> 00:24:15,600
+يؤثر على مادة تسمى الـ Hyaluronic Acid الـ
+
+320
+00:24:15,600 --> 00:24:18,260
+Hyaluronic Acid مادة بتعمل عملية تلاحق ما بين
+
+321
+00:24:18,260 --> 00:24:23,880
+الخلية و تباصق ما بين الخلية فبصير عملية زعزعة
+
+322
+00:24:23,880 --> 00:24:26,660
+الخلايا أو إزالة الخلايا صعب هذا الـ Hyaluronic
+
+323
+00:24:26,660 --> 00:24:32,630
+Acid فبدي مادة تشتغل عليه و تزيلههيالورينك أسد هو
+
+324
+00:24:32,630 --> 00:24:38,050
+مجموعة كبيرة من مجموعة كيومولاس المتحركة التي تجمع
+
+325
+00:24:38,050 --> 00:24:41,850
+الهيالورينك أسد فبالتالي بستخدم إنزيم اسمه
+
+326
+00:24:41,850 --> 00:24:47,850
+هيورينيداز اللي بلعب دوري كتير جدا في إزالة وتقطيع
+
+327
+00:24:47,850 --> 00:24:52,510
+الهيالورينك أسد مما يؤدي إلى إزالة الخلايا ده
+
+328
+00:24:52,510 --> 00:24:56,870
+البروسيجير عادةً يتم تفعيله تحت ميكروسكوب ستيريو
+
+329
+00:24:58,790 --> 00:25:00,970
+الأنواع الأجهزة الموجودة أشهر على الـ
+
+330
+00:25:00,970 --> 00:25:04,990
+Stereomicroscope Indifferent well or micro drop
+
+331
+00:25:04,990 --> 00:25:09,170
+containing content buffer media usually covered by
+
+332
+00:25:09,170 --> 00:25:13,350
+oil on the warm thermoplane Stereomicroscope هو
+
+333
+00:25:13,350 --> 00:25:18,570
+عبارة عن ميكروسكوب الـ stage الخاص بيه بيكون فيه
+
+334
+00:25:18,570 --> 00:25:24,930
+heating stage يعني موصول ببطارية بتعطي حرارةأو
+
+335
+00:25:24,930 --> 00:25:28,710
+heater بيعطي حرارة 37 درجة مئوية عشان تكون قريبة
+
+336
+00:25:28,710 --> 00:25:33,950
+من درجة حرارة الجسم وأنا بستخدم طبق فيه drop أو
+
+337
+00:25:33,950 --> 00:25:37,950
+فيه well كل well فيها media موجود بداخلها البويضات
+
+338
+00:25:37,950 --> 00:25:42,250
+الناضجة ومغطى بال oil عشان أمنع ال contamination
+
+339
+00:25:42,250 --> 00:25:46,330
+دخول أي شيء من الخارج داخل ال media فبالتالي بيؤثر
+
+340
+00:25:46,330 --> 00:25:51,650
+سلبا على البويضاتكيف انا ممكن اسرع و ادى عملية ال
+
+341
+00:25:51,650 --> 00:25:55,470
+removing لل cumulus و ال corona cell بستخدم انزيم
+
+342
+00:25:55,470 --> 00:26:00,790
+اسمه اللي هي lorandase enzyme او ممكن اعمل
+
+343
+00:26:00,790 --> 00:26:04,570
+stripping شو يعني stripping ببساطة جدا بجيب
+
+344
+00:26:04,570 --> 00:26:07,450
+plastic dropper استرايه plastic dropper إلى gauge
+
+345
+00:26:07,450 --> 00:26:12,610
+معين او ديامتر معين هيكون اكبر بقليل او اصغر بقليل
+
+346
+00:26:12,610 --> 00:26:17,220
+من ال oocyteو بعمل suction و releasing suction و
+
+347
+00:26:17,220 --> 00:26:21,020
+releasing حوالي 7-8 مرات خلال عملية ال suction و
+
+348
+00:26:21,020 --> 00:26:23,880
+ال releasing أو ال aspiration و ال releasing لل
+
+349
+00:26:23,880 --> 00:26:27,900
+oocyte بيصير خلخلة في ال cumulus cell و تفتت أنا
+
+350
+00:26:27,900 --> 00:26:30,920
+كده بكون خلصتها بعد ما أعمل عشر مرات في ال drop
+
+351
+00:26:30,920 --> 00:26:34,040
+هذه باخد ال void و بالقلها ل drop جديدة و مظيفة
+
+352
+00:26:34,040 --> 00:26:39,810
+مافيها أي شوائب أو مافي حدث فيهاSuction و
+
+353
+00:26:39,810 --> 00:26:42,430
+Releasing للجوايدات يعني مافيها خلايا طبعا هذه
+
+354
+00:26:42,430 --> 00:26:44,910
+العملية عملية ال aspiration و ال releasing لل
+
+355
+00:26:44,910 --> 00:26:48,750
+oocyte ممكن تكرر بالعدد 20 مرة أو لمدة اعمالها
+
+356
+00:26:48,750 --> 00:26:51,950
+كررها لمدة 30 ثانية يعني انت بدك بالوقت او بدك
+
+357
+00:26:51,950 --> 00:26:58,770
+بالعدد سين once initial cell this خلينا نسميها
+
+358
+00:26:58,770 --> 00:27:04,130
+removing is observed oocyte are removed to the
+
+359
+00:27:04,130 --> 00:27:07,310
+second well droplet containing buffer media taking
+
+360
+00:27:07,310 --> 00:27:11,640
+careto carry over minimum amount of enzyme طبعا
+
+361
+00:27:11,640 --> 00:27:15,560
+هذه ال media ممكن تكون media وفيها انزيم الانزيم
+
+362
+00:27:15,560 --> 00:27:19,120
+المسئول عن خلخلة ال hyaluronic acid بالاضافة إلى
+
+363
+00:27:19,120 --> 00:27:21,740
+ال aspiration و ال releasing فبصير عندي mechanical
+
+364
+00:27:21,740 --> 00:27:26,000
+aspiration releasing و enzymatic وجود الانزيم بعد
+
+365
+00:27:26,000 --> 00:27:30,100
+ما أعمل aspiration و releasing لمدة 30 ثانية بنقل
+
+366
+00:27:30,100 --> 00:27:34,250
+البوايدة هذه إلى قطرة جديدةلم يحدث فيها عملية
+
+367
+00:27:34,250 --> 00:27:37,090
+removing للـ Oocyte طبعاً بكرر هذه العملية مرة و
+
+368
+00:27:37,090 --> 00:27:42,790
+مرتين و تلاتة حتى أتأكد أن كمية الكيوملة السل
+
+369
+00:27:42,790 --> 00:27:47,050
+المحيطة بالـ Oocyte قليلة جداً جداً جداً جداً
+
+370
+00:27:47,050 --> 00:27:50,350
+طبعاً في القطرة الأولى بستخدم الـ dropper بدياميتر
+
+371
+00:27:50,350 --> 00:27:53,370
+معين في القطرة التالية بستخدم الـ dropper بدياميتر
+
+372
+00:27:53,370 --> 00:27:58,070
+أقل لأن كل منقل البويضة من قطرة لقطرة جديدة الـ
+
+373
+00:27:58,070 --> 00:28:01,710
+Oocyte الدياميتر بتقل و الكيوملة السل الحواليها
+
+374
+00:28:01,710 --> 00:28:05,730
+بتقلفبالتالي بدّي Dropper جديدة بـ Diameter أقل
+
+375
+00:28:05,730 --> 00:28:10,250
+عشان أقدر أعمل قوة احتكار أثناء دخول وخرول
+
+376
+00:28:10,250 --> 00:28:17,070
+البوايضة من الفوه .. من الفوهات الأنبوبة طيب،
+
+377
+00:28:17,070 --> 00:28:21,710
+لازم أعمل Washing للـ Oocyte بشكل كامل علشان أوقف
+
+378
+00:28:21,710 --> 00:28:25,810
+عملية عمل الـEnzyme عشان مايضلش فيه Enzyme مرتبط
+
+379
+00:28:25,810 --> 00:28:29,350
+بخلايا الكيوميلاصيل المتبقية وبالتالي أنا بعمل
+
+380
+00:28:29,350 --> 00:28:33,540
+Stopping لعمل الEnzyme فلازم أعملها Washingبعد
+
+381
+00:28:33,540 --> 00:28:36,180
+after partially removal of the cumulus cell by
+
+382
+00:28:36,180 --> 00:28:40,400
+short exposure أو exposure to buffered media
+
+383
+00:28:40,400 --> 00:28:45,960
+contained an enzyme the oocyte are removed and put
+
+384
+00:28:45,960 --> 00:28:49,400
+in the culture media and placed back to the
+
+385
+00:28:49,400 --> 00:28:52,960
+incubator for 30 minutes أنا عملت Deunidation كامل
+
+386
+00:28:52,960 --> 00:28:57,220
+ماخلت ولا cumulus cell حوالين الخلية أو عدد قليل
+
+387
+00:28:57,220 --> 00:29:06,110
+جدا باخد ال oocyte بضيفه في mediaClear Media بدخل
+
+388
+00:29:06,110 --> 00:29:09,530
+الطبق للإنكبيوتر عشان الخلية تستقر لأجل أن أنا
+
+389
+00:29:09,530 --> 00:29:16,030
+كانت مجهدة بفعل وجود الإنزيم وعملية ال aspiration
+
+390
+00:29:16,030 --> 00:29:20,630
+و ال releasing لمدة 30 دقيقة على الأقل قبل ال
+
+391
+00:29:20,630 --> 00:29:25,150
+injection يعني قبل .. ما بين ال stripping و ما بين
+
+392
+00:29:25,150 --> 00:29:29,110
+ال injection في فترة زمانية تسمى rested stage خاصة
+
+393
+00:29:29,110 --> 00:29:34,970
+براحةلازم تحتاجها الـ oocyte عشان لا تجهد في نوع
+
+394
+00:29:34,970 --> 00:29:37,630
+من أنواع الاستقرار المادة الوراثية بداخلها تقدر
+
+395
+00:29:37,630 --> 00:29:43,270
+بتلاتين دقيقة على حد أدنى ف future step أو this
+
+396
+00:29:43,270 --> 00:29:49,890
+future step led to طبعا عملية ال mixing للبوايضة
+
+397
+00:29:49,890 --> 00:29:53,950
+مع ال media اللي بتحتوي على الهيرون ديز as enzyme
+
+398
+00:29:53,950 --> 00:29:58,650
+تعمل عملية tweaking لقوة الترابط ما بين القلاعين
+
+399
+00:29:58,650 --> 00:30:02,680
+فبسهل عملية ال removingبعد الـdenodation الـ
+
+400
+00:30:02,680 --> 00:30:05,480
+Oocyte should be examined under inverted
+
+401
+00:30:05,480 --> 00:30:09,940
+microscope to assess integrity and the stage of
+
+402
+00:30:09,940 --> 00:30:13,480
+maturation عملت الـ denodation جاب المداخلة في الـ
+
+403
+00:30:13,480 --> 00:30:17,980
+incubator لمدة 30 دقيقة طلّق البوادة نقولها عن
+
+404
+00:30:17,980 --> 00:30:20,360
+inverted microscope فشوفها تحت ال inverted
+
+405
+00:30:20,360 --> 00:30:24,440
+microscope شو ال integrity تبعتها؟ جداش ال
+
+406
+00:30:24,440 --> 00:30:28,150
+maturation stage تبعتها؟ هل هي M1 ولا M2؟ولّا أي
+
+407
+00:30:28,150 --> 00:30:31,750
+نوع من أنواع يعني تصلح أم لا تصلح لعملية ال
+
+408
+00:30:31,750 --> 00:30:36,030
+fertilization the incomplete denodation of oocyte
+
+409
+00:30:36,030 --> 00:30:39,710
+before eggsy يعني في بعض الناس بيقولك لأ أنا بتعمل
+
+410
+00:30:39,710 --> 00:30:43,810
+complete denodation ما بتخلي أي cumula cell بهدوء
+
+411
+00:30:43,810 --> 00:30:47,030
+لازم يكون فيه جزء من ال cumula cell لأن هذا بيفيد
+
+412
+00:30:47,030 --> 00:30:50,430
+ال oocyte كيف بيفيد ال oocyte؟ لأنه في دراسات
+
+413
+00:30:50,430 --> 00:30:54,710
+بتقولك عملية ال denodation الغير كاملة يعني التي
+
+414
+00:30:54,710 --> 00:30:57,950
+تترك عدد قليل من ال cumula cellطبقة محيطة بالـ
+
+415
+00:30:57,950 --> 00:31:02,030
+Oocyte تساعد في تحسين جودة الـ embryo بعد ال
+
+416
+00:31:02,030 --> 00:31:05,730
+fertilization وتساعد في تحسين الـ developmental
+
+417
+00:31:05,730 --> 00:31:10,230
+embryo أيضًا تلعب دور كبير جدًا في الـ assist
+
+418
+00:31:10,230 --> 00:31:13,770
+embryonic metabolism و ال stimulation gene
+
+419
+00:31:13,770 --> 00:31:17,810
+expression تعمل reduction لل oxidative stress يعني
+
+420
+00:31:17,810 --> 00:31:22,490
+مش شضارة ولا دقة في الأداء إنك تتعرّض الخلية بشكل
+
+421
+00:31:22,490 --> 00:31:26,740
+الكامل و ما تخلّي أي كيوم للسلحة حولها، لأخفف قدر
+
+422
+00:31:26,740 --> 00:31:31,100
+الإمكان و افقي و لو two layers حوالها عدد قليل من
+
+423
+00:31:31,100 --> 00:31:34,060
+الخلايا إنك انت ماتضرك الخلايا أثناء عملية ال
+
+424
+00:31:34,060 --> 00:31:38,840
+injection و ماتضر الجنين لإن وجودها مفيد في أربع
+
+425
+00:31:38,840 --> 00:31:42,820
+أو خمس نقاط بتساعد ال embryo quality أو بتحسن ال
+
+426
+00:31:42,820 --> 00:31:46,260
+embryo quality و ال embryo development و بتعمل أسس
+
+427
+00:31:46,260 --> 00:31:49,560
+embryonic metabolism بتعمل stimulation لـ Angelic
+
+428
+00:31:49,560 --> 00:31:52,440
+suppression وتعمل reduction لل oxidative stress
+
+429
+00:31:52,440 --> 00:31:59,330
+خمس فوائدمهمة لبقاء كمية من كيومة الـ cell حوالين
+
+430
+00:31:59,330 --> 00:32:06,350
+الـ Oocyte طبعا هذه ببساطة جدا شكل الـ Oocyte لما
+
+431
+00:32:06,350 --> 00:32:11,050
+تطلع هذه شكل الـ Oocyte لما تطلع من ال fluid و أنا
+
+432
+00:32:11,050 --> 00:32:13,850
+أحصلها من ال fluid لو أنقلها لقطرة جديدة هذه بتكون
+
+433
+00:32:13,850 --> 00:32:19,470
+كلها عبارة عن الـ Oocyte ولكن لو أنا فرغت هذه الـ
+
+434
+00:32:19,470 --> 00:32:24,350
+Oocyteوهذه كلها cumulus cell و corona cell حوالها
+
+435
+00:32:24,350 --> 00:32:28,310
+بعد ال denodation لازم تكون بهذا الشكل طبعا هذا
+
+436
+00:32:28,310 --> 00:32:31,470
+اللي باللون الأحمر هذا خلينا نسميه هذا ال zoona
+
+437
+00:32:31,470 --> 00:32:35,490
+وهذا ال polar body وهذا ال polar body وهذه كلها
+
+438
+00:32:35,490 --> 00:32:42,550
+طبقة من ال cytoplasm هاي ال oocyte اللي باللون
+
+439
+00:32:42,550 --> 00:32:46,290
+الأخضر الفاتح بيسموها cumulus cell اللي باللون
+
+440
+00:32:46,290 --> 00:32:50,520
+الأخضر الداكن موريلا وهذا ال thica cellطبعاً لما
+
+441
+00:32:50,520 --> 00:32:55,100
+أجى أعمل aspiration و releasing سكشن و releasing
+
+442
+00:32:55,100 --> 00:33:00,740
+هتروح كل هدوء يدل اللي باللون الأخضر الفاتح و هي
+
+443
+00:33:00,740 --> 00:33:04,840
+الكيومولا السل لازم انا اتجنب كمية كبيرة جدا ال
+
+444
+00:33:04,840 --> 00:33:08,880
+granulosa cell هي عبارة عن خليط من الموريلا cell و
+
+445
+00:33:08,880 --> 00:33:15,650
+الكيومولا cell دعونانرى هذا الفيديو المتعلق بعملية
+
+446
+00:33:15,650 --> 00:33:20,270
+ال denotation علشان تكون الأمر أوضح ان شاء الله
+
+447
+00:33:20,270 --> 00:33:27,090
+طبعا
+
+448
+00:33:27,090 --> 00:33:34,970
+هيتكلم عن ال denotation تحت ال microscope طبعا
+
+449
+00:33:34,970 --> 00:33:38,290
+هذه ال pasteur tube او pasteur pipet او dropper
+
+450
+00:33:38,290 --> 00:33:43,280
+طبعا هنا هذه البوايضات الليموجودة فيها بيعمل
+
+451
+00:33:43,280 --> 00:33:45,780
+suction بداخل البيضات للداخل وبعدين بيعملها
+
+452
+00:33:45,780 --> 00:33:49,040
+releasing أكتر من مرة وشوف كيف بيصير تفتت لل
+
+453
+00:33:49,040 --> 00:33:49,500
+cumulus
+
+454
+00:34:24,960 --> 00:34:27,440
+و اخدوا بالكوا في الخطوة التانية اغير ال pipet يا
+
+455
+00:34:27,440 --> 00:34:31,580
+بابت اقل ال diameter تبعها اقل لان الخلية او
+
+456
+00:34:31,580 --> 00:34:35,120
+البويضة فقدت الجرانيلوزا سيل فقدت الكيوركيوميلاس
+
+457
+00:34:35,120 --> 00:34:39,120
+سيل فصغر حجمها فابدي ب steer pipet ال diameter اقل
+
+458
+00:35:22,520 --> 00:35:25,720
+شايفين في كل مرة بيعمل aspiration و releasing
+
+459
+00:35:25,720 --> 00:35:29,140
+بيعمل في منطقة جديدة علشان ما يصير الشواقب حوالها
+
+460
+00:35:29,140 --> 00:35:33,320
+و في كل مرة بعد فترة زمنية بعد ما يعمل يعني خمسين
+
+461
+00:35:33,320 --> 00:35:37,700
+عشر مرات عشرين مرة خمسين ثانية بنقل هذه ال oxide
+
+462
+00:35:37,700 --> 00:35:40,300
+كلها بداخلها داخل ال dropout او داخل ال pasture
+
+463
+00:35:40,300 --> 00:35:41,940
+pipe و بنقلها ل drop جديد
+
+464
+00:36:07,360 --> 00:36:10,260
+شوف كيف شكل البويضات هي عندي واحدة ..تنتين ..تلاتة
+
+465
+00:36:10,260 --> 00:36:12,840
+..اربعة ..خمسة ..ستة ..سبعة ..تمانية ..عشرة
+
+466
+00:36:12,840 --> 00:36:16,220
+..احداشر بويضة من سيدة واحدة اللي كانت مفروضة تطلع
+
+467
+00:36:16,220 --> 00:36:19,500
+فقط تلت بويضات كحد أقصى هذا طبعا بعد ال
+
+468
+00:36:19,500 --> 00:36:25,200
+stimulation هذه
+
+469
+00:36:25,200 --> 00:36:28,320
+طريقة ال stripping أو ال denodation الخاصة
+
+470
+00:36:28,320 --> 00:36:30,660
+بالاواصيت خليني أشوف فيديو تاني يتكلم عن هذا
+
+471
+00:36:30,660 --> 00:36:31,120
+الموضوع
+
+472
+00:36:37,110 --> 00:36:40,190
+طبعا هذا شكل البوايضات أول ما نحزلهم من ال fluid
+
+473
+00:36:40,190 --> 00:36:42,990
+أو من ال flucular fluid بكون شكلهم بهذا الشكل زي
+
+474
+00:36:42,990 --> 00:36:45,790
+ما شوفناها تحت الصورة هذه البوايضة و هذه كل
+
+475
+00:36:45,790 --> 00:36:49,830
+الثيكاسيل و الكيملاسسيل و ال موريلاسيل و ال
+
+476
+00:36:49,830 --> 00:36:53,410
+somatic cell كلها محيطة فيها بده يعملها pipetting
+
+477
+00:36:53,410 --> 00:36:59,370
+هالوقت بيجي بالدربر بيعملها suction و releasing
+
+478
+00:36:59,370 --> 00:37:06,230
+لمدة تلاتين ثانية على الأقل مش وجدش ال diameter
+
+479
+00:37:08,580 --> 00:37:11,900
+الخاصة بال بستير بايبت أو الخاصة بالدروبة اللي
+
+480
+00:37:11,900 --> 00:37:15,740
+لازم تكون استراتيك خمسة، ستة، سبعة، تمان مرات أو
+
+481
+00:37:15,740 --> 00:37:22,100
+تلاتين ثانية كحد أدنى و بعدين بيعملهم transfer إلى
+
+482
+00:37:22,100 --> 00:37:25,880
+a new drop علشان يتخلص من كمية الشباب هاي فال new
+
+483
+00:37:25,880 --> 00:37:29,980
+drop عملها releasing و بعدين بيعملهم suction و
+
+484
+00:37:29,980 --> 00:37:33,640
+releasing بس بده يغير ال bybitتغير بايبت لأنه بده
+
+485
+00:37:33,640 --> 00:37:38,020
+بايبت الديامتر تبعته أقل علشان يقدر يصير قوة
+
+486
+00:37:38,020 --> 00:37:42,300
+احتكاك ما بين الجدار الداخل للأنبوبة و البويضة
+
+487
+00:37:42,300 --> 00:37:45,800
+واحدة واحدة و في بعضهم بيعملها كاملة ولكن افضل
+
+488
+00:37:45,800 --> 00:37:49,980
+واحدة واحدة علشان مايصيرش تزاحم و مما يدى لتهتك
+
+489
+00:37:49,980 --> 00:37:54,800
+الخلايا في بعض الأحيان ممكن يعيدها تلاتين ثانية زي
+
+490
+00:37:54,800 --> 00:37:59,200
+ما قلنا و ينتقل إلى drop جديدة فيما بعد هينقل إلى
+
+491
+00:37:59,200 --> 00:38:04,880
+drop جديدة هيغير ال بايبتالمفروض يغير الـ Pivot
+
+492
+00:38:04,880 --> 00:38:09,980
+علشان يعطيني نتائج أفضل يعطيني Diameter Pivot with
+
+493
+00:38:09,980 --> 00:38:15,580
+low diameter اكبر
+
+494
+00:38:15,580 --> 00:38:21,900
+البوايضات هتشوفهم بهذا الشكل هذه فكرة الـ
+
+495
+00:38:21,900 --> 00:38:25,800
+Denotation بشكل أساسي كيف بتصير عملية الـ
+
+496
+00:38:25,800 --> 00:38:29,760
+Denotation اتعرفنا عنها بعد ما حكينا عن الـ
+
+497
+00:38:29,760 --> 00:38:32,900
+Denotationالـ timing للـ oocyte denodation الـ
+
+498
+00:38:32,900 --> 00:38:37,160
+oocyte denodation is usually performed between 37
+
+499
+00:38:37,160 --> 00:38:42,220
+and 40 hours after HCG يعني عملية الـ denodation
+
+500
+00:38:42,220 --> 00:38:46,360
+بتصير بعد عملية ال injection للشريجون أو لل human
+
+501
+00:38:46,360 --> 00:38:50,540
+chronic gonadotropin اللي بيعمل ovulation بـ 37
+
+502
+00:38:50,540 --> 00:38:56,050
+إلى 40 ساعة ولكن يجب أن تحدثقبل الـ insemination
+
+503
+00:38:56,050 --> 00:39:00,250
+بساعة أو نص ساعة على الأقل الإنزيمات التي تستخدم
+
+504
+00:39:00,250 --> 00:39:04,670
+وتركيزها بشكل عام وtraditionally الـdenodation أو
+
+505
+00:39:04,670 --> 00:39:09,050
+الـ denoding process أو procedure involve a
+
+506
+00:39:09,050 --> 00:39:14,670
+poivrein derivative هيلورينيدازي يعني هيلورينيدازي
+
+507
+00:39:14,670 --> 00:39:19,490
+مع مشتق من الـpoivrein بشكل أساسي in order to
+
+508
+00:39:19,490 --> 00:39:23,130
+minimum any potential toxic effect on oocyte for
+
+509
+00:39:23,130 --> 00:39:26,420
+this type of enzymewe should be reduce the
+
+510
+00:39:26,420 --> 00:39:28,440
+enzymatic concentration or the enzyme
+
+511
+00:39:28,440 --> 00:39:33,340
+concentration or reduce that duration for oocyte
+
+512
+00:39:33,340 --> 00:39:37,640
+exposure to this type of enzyme يعني أنا ممكن أجلل
+
+513
+00:39:37,640 --> 00:39:39,840
+ال toxicity الخاصة بهذا الانزيم بطريقة تانية
+
+514
+00:39:39,840 --> 00:39:43,500
+الطريقة الأولى أنه أجلل ال time اللي بتتعرض فيه
+
+515
+00:39:43,500 --> 00:39:47,540
+الخلية لهذا الانزيم أو أجلل ما يُعرف باسم ال
+
+516
+00:39:47,540 --> 00:39:50,440
+concentration الخاصة فيه وفي بعضهم بيجلد ال time
+
+517
+00:39:50,440 --> 00:39:54,760
+أفضل لإن ال concentration بيكون fixedأقل الـ
+
+518
+00:39:54,760 --> 00:39:57,540
+concentration ممكن أن أستخدم خلال الـ denotation
+
+519
+00:39:57,540 --> 00:40:02,040
+80 international units per milliliter يعني لو الـ
+
+520
+00:40:02,040 --> 00:40:05,620
+one drop فيها 80 unit ممكن أن أضع هذه الـ one drop
+
+521
+00:40:05,620 --> 00:40:10,520
+من الإنزيم على 1 مليليتر من ال media وكل ما كان
+
+522
+00:40:10,520 --> 00:40:15,620
+أقل تركيزه وكل ما كان تأثير السلبي أقل أو ال
+
+523
+00:40:15,620 --> 00:40:20,830
+toxicity أقل فممكن أناأخفض درجة حرارته .. عفوا ..
+
+524
+00:40:20,830 --> 00:40:24,870
+أخفض تركيزه وأخفض effect تبعته إن أستخدم تركيز
+
+525
+00:40:24,870 --> 00:40:28,470
+عشرة international unit per milliliter بعض
+
+526
+00:40:28,470 --> 00:40:32,170
+الدراسات قالت إن هذا التركيز has also been shown
+
+527
+00:40:32,170 --> 00:40:37,970
+to be able to make denotation for mature oocyte
+
+528
+00:40:37,970 --> 00:40:43,150
+بشكل عالي جدا يعني العشرة international unit قادرة
+
+529
+00:40:43,150 --> 00:40:46,190
+أن تعمل denotation وبكفاءة عالية جدا فأنا ليش
+
+530
+00:40:46,190 --> 00:40:49,690
+أستخدم التمانين؟فلو بدى أستخدم الـ 80 بدي أقلل ال
+
+531
+00:40:49,690 --> 00:40:53,490
+duration لازم
+
+532
+00:40:53,490 --> 00:40:57,230
+أقلل ال duration خلصنا كده من عملية ال denodation
+
+533
+00:40:57,230 --> 00:40:59,790
+و ال stripping جاهز لعملية ال injection اللى
+
+534
+00:40:59,790 --> 00:41:04,570
+هناخدها في الشكتر الجديد ولكن قبل ما نخلص الموضوع
+
+535
+00:41:04,570 --> 00:41:09,570
+ده فيه موضوع صغير بتنوح له وهو هرمون ال EAMH ال
+
+536
+00:41:09,570 --> 00:41:14,170
+EAMH ببساطة جدا يا طلابنا الأعزاء هو عبارة عن
+
+537
+00:41:14,170 --> 00:41:18,730
+هرمون يطلق عليه protein هرمونيُفرز بشكل أساسي من
+
+538
+00:41:18,730 --> 00:41:22,350
+الـ granulosa cell in the ovarian follicle in the
+
+539
+00:41:22,350 --> 00:41:27,130
+ovarian follicle لما تكون أو يكون عند سيدة تفرز ال
+
+540
+00:41:27,130 --> 00:41:29,830
+ovarian follicle هرمون أو ال granulosa cell
+
+541
+00:41:29,830 --> 00:41:32,250
+الموجودة في ال ovarian follicle تفرز هرمون
+
+542
+00:41:32,250 --> 00:41:35,590
+antimolarin هرمون خدوا بالك هذا الهرمون مهم جدا
+
+543
+00:41:35,590 --> 00:41:39,790
+وبناء عليه بعض الأضطراب بيستخدموه عشان يحددوا هدى
+
+544
+00:41:39,790 --> 00:41:43,630
+الزوجة أو هدى السيدة تروح agonist أو antagonist
+
+545
+00:41:43,630 --> 00:41:48,700
+short protocol ولا long protocolوبعضهم بيستخدم ال
+
+546
+00:41:48,700 --> 00:41:51,740
+A match عشان يحدد ال shorter protocol أو ال longer
+
+547
+00:41:51,740 --> 00:41:55,840
+protocol شو هيختار طبعا ال A match level بلعب دور
+
+548
+00:41:55,840 --> 00:42:01,120
+كبير جدا حيث أنه يزيد بعد ال 25 سنة عند السيدات
+
+549
+00:42:01,120 --> 00:42:05,800
+ويبدأ في التناقص بعد ال 30 أو عند 30 سنة ال A
+
+550
+00:42:05,800 --> 00:42:10,060
+match بلعب دور كبير جدا في ال development of sex
+
+551
+00:42:10,060 --> 00:42:15,400
+organ في ال unborn baby كيف بلعب هذا الدور؟بقولك
+
+552
+00:42:15,400 --> 00:42:20,420
+ببساطة جدا في أول أسابيع من الحمل ال baby will be
+
+553
+00:42:20,420 --> 00:42:24,240
+start reproductive organ development إذا كان ال
+
+554
+00:42:24,240 --> 00:42:28,960
+baby male فهيفرس كمية كبيرة جدا من ال AMH علشان
+
+555
+00:42:28,960 --> 00:42:33,700
+يمنع تكوين بالإضافة طبعا إلى ال male hormone علشان
+
+556
+00:42:33,700 --> 00:42:40,180
+يمنع تكوين ال female organ development ويسمح
+
+557
+00:42:40,180 --> 00:42:47,160
+بتكوين ال maledeveloped male organ يعني ال AMH
+
+558
+00:42:47,160 --> 00:42:52,860
+يفرز في المرحلة الجنينية إذا كان الجنين ذكر يفرز
+
+559
+00:42:52,860 --> 00:42:57,680
+كمية كبيرة جدا من ال AMH plus ال sex hormone الخاص
+
+560
+00:42:57,680 --> 00:43:02,460
+بالذكور مما يمنع تكوين ال organ الخاص بال female
+
+561
+00:43:02,460 --> 00:43:08,060
+organويسمح ويساعد على إنتاج وتكوين ال organ الخاص
+
+562
+00:43:08,060 --> 00:43:13,340
+بالمال لو كان العكس عند ال unborn baby في المرحلة
+
+563
+00:43:13,340 --> 00:43:17,500
+الجنينية female كمية اللي قد أبقاش هتقل، هتكون أقل
+
+564
+00:43:17,500 --> 00:43:23,940
+ما يمكن و تكاد تكون غير مذكورة مما يسمح بظهور ال
+
+565
+00:43:23,940 --> 00:43:27,680
+organ related with female و عدم ظهور ال organ
+
+566
+00:43:27,680 --> 00:43:33,510
+related with male مما يؤدي إلى ظهور الجنين كجنين
+
+567
+00:43:33,510 --> 00:43:39,230
+أنثى عشان كده بعض الأطباء وبعض المراكز ممكن تستخدم
+
+568
+00:43:39,230 --> 00:43:42,570
+ال AMH تحديد مستوى ال AMH في المرحلة الجنينية
+
+569
+00:43:42,570 --> 00:43:47,470
+لتحديد جنس المولود هل هو male أو female إذا كان
+
+570
+00:43:47,470 --> 00:43:53,050
+مستوى عالي جدا بيكون male إذا كان مستوى منخفض أو
+
+571
+00:43:53,050 --> 00:44:00,970
+منعدم بيكون female لإن وجوده يسمح بإنشاء الأعضاء
+
+572
+00:44:00,970 --> 00:44:06,920
+الذكريةيمنع تكوين الأعضاء الجنثوية في المرحلة
+
+573
+00:44:06,920 --> 00:44:11,540
+الجنينية طبعاً الـ AMH has a different role for
+
+574
+00:44:11,540 --> 00:44:17,360
+female from or after puberty at the time of his
+
+575
+00:44:17,360 --> 00:44:21,020
+beginning making AMH the more egg cell there are
+
+576
+00:44:21,020 --> 00:44:25,400
+the high level of AMH ال AMH يمكن أن يستخدم as
+
+577
+00:44:25,400 --> 00:44:29,610
+marker or indicator for ovarian responseجدّيش أنا
+
+578
+00:44:29,610 --> 00:44:32,870
+عند مستوى الـ AMH عند السيدات جدّيش بكون عندها
+
+579
+00:44:32,870 --> 00:44:36,810
+مخزون في المبيض ففي علاقة طردية ما بين مستوى الـ
+
+580
+00:44:36,810 --> 00:44:40,950
+AMH ومخزون المبيض كل ما كان الـ AMH عالي، معناه
+
+581
+00:44:40,950 --> 00:44:45,570
+فيه بيبايدات كتير جدا عند السيدة الـ AMH يمكن أن
+
+582
+00:44:45,570 --> 00:44:50,710
+يستخدم ليه؟ predict for started monobios متى كل ما
+
+583
+00:44:50,710 --> 00:44:54,770
+كان قليل المنوبيوز بتكون أقرب يستخدم في تشخيص الـ
+
+584
+00:44:54,770 --> 00:44:57,530
+polycystic ovarian syndrome ال hormonal disorder
+
+585
+00:44:58,580 --> 00:45:02,840
+يستخدم في .. for infant .. infant .. chick infant
+
+586
+00:45:02,840 --> 00:45:06,260
+with genital that are not clear identified عند ال
+
+587
+00:45:06,260 --> 00:45:10,700
+male و female monitoring women who have some type
+
+588
+00:45:10,700 --> 00:45:15,000
+of ovarian cancer we can use it as indicator for
+
+589
+00:45:15,000 --> 00:45:18,640
+fertility in women specifically in relation to the
+
+590
+00:45:18,640 --> 00:45:25,740
+number of egg in reserve of ovaries so AMHcan be
+
+591
+00:45:25,740 --> 00:45:30,740
+used as indicator for ovarian response and ovarian
+
+592
+00:45:30,740 --> 00:45:34,440
+reserve
+
+593
+00:45:34,440 --> 00:45:40,540
+على مخزون المبيض ومدى استجابة المبيض so we can use
+
+594
+00:45:40,540 --> 00:45:44,160
+a match as a predictor for ovarian reserve and
+
+595
+00:45:44,160 --> 00:45:48,000
+ovarian response سوف نكتفي بهذا القدر في المحاضرة
+
+596
+00:45:48,000 --> 00:45:51,380
+اليوم على أن نكمل ما تبقى من هذا ال chapter في
+
+597
+00:45:51,380 --> 00:45:54,020
+المحاضرة القادمة ان شاء الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/N-8xgiNju1w_postprocess.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/N-8xgiNju1w_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..a86dd5a397c8d8d779f847546f506020f79a37eb
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/N-8xgiNju1w_postprocess.srt
@@ -0,0 +1,1588 @@
+1
+00:00:00,960 --> 00:00:04,200
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:04,200 --> 00:00:09,020
+المرسلين سيدنا محمد وعلى آله وصاحبه أجمعين طلابنا
+
+3
+00:00:09,020 --> 00:00:12,720
+الأعزاء نرجو من الله الكريم أن تكونوا جميعا بخير و
+
+4
+00:00:12,720 --> 00:00:16,840
+بصحة جيدة استكمالا لما بدأنا فيه في المحاضرة
+
+5
+00:00:16,840 --> 00:00:21,080
+السابقة تحدثنا عن الآليات والطرق التي يمكن أن
+
+6
+00:00:21,080 --> 00:00:24,780
+تستخدم من أجل تحضير عينة السائل الحطن المجهري أو
+
+7
+00:00:24,780 --> 00:00:29,060
+التلقيح الصناعيواتطرحنا إلى ثلاث طرق أساسية طريقة
+
+8
+00:00:29,060 --> 00:00:32,560
+الأولى طريقة الـ Simple Washing Method طريقة تليها
+
+9
+00:00:32,560 --> 00:00:36,080
+طريقة الـ Swamp Up و الأكثر استخداما في حالة الـ
+
+10
+00:00:36,080 --> 00:00:39,840
+IOI أو الـ IVF الـ Traditional IVF و الطريقة
+
+11
+00:00:39,840 --> 00:00:43,060
+الثالثة هي عبارة عن الـ Density Gradient
+
+12
+00:00:43,060 --> 00:00:47,020
+Centrifugation and this method will be used in IGZ
+
+13
+00:00:47,020 --> 00:00:52,560
+or during IGZ process اليوم سوف نستكمل هذا الأمر
+
+14
+00:00:52,560 --> 00:00:57,220
+في التعرف على طرق أخرىيمكن من خلالها الحصول على
+
+15
+00:00:57,220 --> 00:01:03,060
+عينة السمن في حالات معينة تعتبر حالات مرضية تحت
+
+16
+00:01:03,060 --> 00:01:09,020
+مصطلح تيسا أو تيسي، بيسا أو ميسا شو معنى هذه
+
+17
+00:01:09,020 --> 00:01:14,960
+المصطلحات وما المقصود بها في المحاضرة السابقة
+
+18
+00:01:14,960 --> 00:01:20,540
+تكلمنا عن مصطلح asospermia وهو عدد عدم وجود
+
+19
+00:01:20,540 --> 00:01:25,040
+spermatozoa في السمن الفلويدوقُسمت Clinical من
+
+20
+00:01:25,040 --> 00:01:27,820
+ناحية كليكية إلى Obstructive وNon-obstructive
+
+21
+00:01:27,820 --> 00:01:31,740
+Azospermia والـ Obstructive Azospermia هي عبارة عن
+
+22
+00:01:31,740 --> 00:01:36,320
+عدم وجود سبرماتوزوة في السمن الفلويد بفعل خلل
+
+23
+00:01:36,320 --> 00:01:39,680
+ميكانيكي يسمى Mechanical Blockage في الـ Vase
+
+24
+00:01:39,680 --> 00:01:43,840
+Difference أو الـ Ejaculatory Duct أو الـ
+
+25
+00:01:43,840 --> 00:01:47,620
+Epidermis معناة تلاتة هدولة، تلاتة مناطق هذه فيها
+
+26
+00:01:47,620 --> 00:01:52,080
+Blockage فأثدت إلى عدم خروج لسبرماتوزوة من المصنع
+
+27
+00:01:53,210 --> 00:01:56,670
+قسموهم الـ Obstructive Azoospermia إلى Acquired و
+
+28
+00:01:56,670 --> 00:01:59,890
+Congenital الـ Acquired إن الإنسان كان طبيعي و
+
+29
+00:01:59,890 --> 00:02:03,470
+فجأة تعرض إلى حادث معين حدث عنده Obstructive
+
+30
+00:02:03,470 --> 00:02:07,490
+Azoospermia زي الـ Vasectomy الـ Post Infection
+
+31
+00:02:07,490 --> 00:02:12,150
+Disease Surgical Operation أو أي مشكلة في منطقة
+
+32
+00:02:12,150 --> 00:02:17,190
+الـ Abdominal أو منطقة الـ Pelvic أو صاروا Trauma
+
+33
+00:02:17,190 --> 00:02:18,670
+في منطقة الـ Reproductive System
+
+34
+00:02:21,980 --> 00:02:24,080
+الـ Congenital Obstructive Azoospermia الـ
+
+35
+00:02:24,080 --> 00:02:27,560
+Congenital Obstructive Azoospermia إن الطفل الذكر
+
+36
+00:02:27,560 --> 00:02:31,380
+يولد بعدم موجود لا إبداد مصر ولا Fast Difference
+
+37
+00:02:31,380 --> 00:02:36,380
+ولا Ejaculatory Duct أو واحد منهم مختفي أو بمعنى
+
+38
+00:02:36,380 --> 00:02:40,000
+آخر عنده مشكلة في الـ Prostatic Cyst أو مرحلة
+
+39
+00:02:40,000 --> 00:02:44,340
+بنسميها Young Syndrome طبعا هذا Genetic بشكل عام
+
+40
+00:02:44,340 --> 00:02:48,720
+وبشكل أساسي طبعا هذه هي عبارة عن الأسباب التي تؤدي
+
+41
+00:02:48,720 --> 00:02:52,610
+وتقصي وتقسيمات الـ Obstructive Azoospermiaأما
+
+42
+00:02:52,610 --> 00:02:55,490
+بالنسبة لتقسيمات الـ Non-obstructive Azospermia
+
+43
+00:02:55,490 --> 00:02:59,290
+فحكينا إن الـ Non-obstructive إن هذا الإنسان طبيعي
+
+44
+00:02:59,290 --> 00:03:03,050
+بكل نواقله المخصص بالـ Reproductive tract موجودة
+
+45
+00:03:03,050 --> 00:03:07,890
+وطبيعية ولكن تعرض إلى أمور أدت إلى حدوث خلل في
+
+46
+00:03:07,890 --> 00:03:11,510
+المصدر، في المصنع، في الـ Testis زي الـ Endocrine
+
+47
+00:03:11,510 --> 00:03:16,110
+abnormality زي الـ Genetic abnormality كرومزوم الـ
+
+48
+00:03:16,110 --> 00:03:18,570
+abnormality أنبلود الـ Translocation الـ Y
+
+49
+00:03:18,570 --> 00:03:20,550
+-microchromosome deletion abnormality في
+
+50
+00:03:20,550 --> 00:03:24,660
+الكاريوتيبلفي عنده post infection، في عنده trauma،
+
+51
+00:03:24,660 --> 00:03:28,020
+في عنده environment toxic exposure to radiation or
+
+52
+00:03:28,020 --> 00:03:30,740
+chemotherapy or radiotherapy exposure to heavy
+
+53
+00:03:30,740 --> 00:03:37,200
+metal and varicose veins this point أو هذه النقات
+
+54
+00:03:37,200 --> 00:03:41,660
+تعتبر من أكثر النقات التي تؤدي إلى حدوث non
+
+55
+00:03:41,660 --> 00:03:46,380
+-obstructive azospermia طيب السؤال اللي بترح نفسه
+
+56
+00:03:46,380 --> 00:03:50,870
+إنسان في عنده seminal fluidولكن بدون وجود
+
+57
+00:03:50,870 --> 00:03:56,470
+spermatozoa في السمن قد يكون obstructive و قد يكون
+
+58
+00:03:56,470 --> 00:04:00,070
+non-obstructive إذا كان obstructive الأمر بسيط
+
+59
+00:04:00,070 --> 00:04:05,930
+بعملية جروحية يعالج الأمر إذا كان هذا obstructive
+
+60
+00:04:05,930 --> 00:04:10,530
+إذا كان non-obstructive فبلجأ إلى الحصول على ال
+
+61
+00:04:10,530 --> 00:04:13,730
+spermatozoa من المصنع المباشرة يعني بمعنى آخر
+
+62
+00:04:13,730 --> 00:04:16,750
+طالما ال Epidermis موجود و ال vas deferens موجود
+
+63
+00:04:17,120 --> 00:04:21,760
+والتستش موجود قادر على إنتاج الـ spermatozoa ولكن
+
+64
+00:04:21,760 --> 00:04:25,260
+في عندها مشكلة ما بتقدر تخرج ال spermatozoa فبلجأ
+
+65
+00:04:25,260 --> 00:04:28,560
+إلى الوصول إلى ال spermatozoa بشكل مباشر و الحصول
+
+66
+00:04:28,560 --> 00:04:32,620
+عليها سواء كان في عندي obstructive أو في عندي non
+
+67
+00:04:32,620 --> 00:04:36,960
+-obstructive بشرط ما يكون عندي complete failure في
+
+68
+00:04:36,960 --> 00:04:40,120
+ال testicle function في ال non-obstructive ساعتها
+
+69
+00:04:40,120 --> 00:04:44,080
+بقدر أحصل على spermatozoa من المصنع طب كيف بحصل
+
+70
+00:04:44,080 --> 00:04:48,420
+على spermatozoa في تلت مصطلحات أساسيةبريكتانيوس
+
+71
+00:04:48,420 --> 00:04:56,860
+بيدمل sperm aspiration هذا بيسميها PECA PECA PECA
+
+72
+00:04:56,860 --> 00:04:59,460
+PECA PECA PECA PECA PECA PECA PECA PECA PECA PECA
+
+73
+00:04:59,460 --> 00:04:59,520
+PECA PECA PECA PECA PECA PECA PECA PECA PECA PECA
+
+74
+00:04:59,520 --> 00:04:59,580
+PECA PECA PECA PECA PECA PECA PECA PECA PECA PECA
+
+75
+00:04:59,580 --> 00:05:02,400
+PECA PECA PECA PECA PECA PECA PECA PECA PECA PECA
+
+76
+00:05:02,400 --> 00:05:03,380
+PECA PECA PECA PECA PECA PECA PECA PECA PECA PECA
+
+77
+00:05:03,380 --> 00:05:11,600
+PECA PECA PECA PECA PECA
+
+78
+00:05:11,600 --> 00:05:15,820
+P
+
+79
+00:05:16,070 --> 00:05:19,970
+أختصار لـ testicular sperm aspiration وفي مصطلح
+
+80
+00:05:19,970 --> 00:05:23,770
+تاني بسميه TSA وهو عبارة عن testicular sperm
+
+81
+00:05:23,770 --> 00:05:28,610
+extraction أن أنا باخد sperm مباشرة بدون ما أعمل
+
+82
+00:05:28,610 --> 00:05:32,150
+aspiration طبعاً this is the method for harvest
+
+83
+00:05:32,150 --> 00:05:36,110
+sperm from the testicular in obstructed aspermia
+
+84
+00:05:36,110 --> 00:05:39,710
+يعني التلات مصطلحات هذه أو الأربعة هي المصطلحات
+
+85
+00:05:39,710 --> 00:05:43,290
+التي يمكن أن تستخدم للحصول و الوصول
+
+86
+00:05:47,440 --> 00:05:52,320
+obstructive azospermia يعني التستشغالة ولكن
+
+87
+00:05:52,320 --> 00:05:56,740
+النواقل فيها مشكلة in contrast, open testicular
+
+88
+00:05:56,740 --> 00:06:00,440
+sperm extraction تيسيه using single or multi
+
+89
+00:06:00,440 --> 00:06:06,420
+-biopsy and تيسيه with the aid of microsurgical R
+
+90
+00:06:06,420 --> 00:06:09,500
+-method to harvest sperm from man with non
+
+91
+00:06:09,500 --> 00:06:13,980
+-obstructive azospermia يعني بمعنى آخر أن ممكن أن
+
+92
+00:06:13,980 --> 00:06:17,930
+أعمل أكتر من biopsy في هذه الحالةإن تم فشل الـ
+
+93
+00:06:17,930 --> 00:06:21,190
+biopsy الأولى والـ biopsy التانية فالـ TSA هي
+
+94
+00:06:21,190 --> 00:06:26,230
+الأكثر استخداما أيضا في الـ non-obstructive
+
+95
+00:06:26,230 --> 00:06:30,950
+azoospermia الـ non-obstructive azoospermia تمام؟
+
+96
+00:06:30,950 --> 00:06:35,270
+مين هي؟ اللي هي سمناها microdissection testicular
+
+97
+00:06:35,270 --> 00:06:42,250
+sperm extraction أو micro TSA micro TSA صورة بتوضح
+
+98
+00:06:42,250 --> 00:06:47,400
+الكلام اللي أنا قلته خلّينا نبدأ من اليمينTC من
+
+99
+00:06:47,400 --> 00:06:52,580
+يمين أعلى الشاشة شايف أنا باخد بيوبسي tissue من ال
+
+100
+00:06:52,580 --> 00:06:57,440
+testis مباشرة التي تقابلها باخد aspiration من ال
+
+101
+00:06:57,440 --> 00:07:00,880
+fluid الموجود في ال testis الصورة السفلة على
+
+102
+00:07:00,880 --> 00:07:03,960
+اليمين باخد aspiration ال fluid من ال epidermis
+
+103
+00:07:03,960 --> 00:07:09,420
+واللي وراها باخد aspiration من ال epidermis ولكن
+
+104
+00:07:09,420 --> 00:07:14,580
+باختراق هنا في الأولى من الأسفل مباشرة ال needle
+
+105
+00:07:14,580 --> 00:07:19,750
+بتروح علىهي بتدمس يعني بيصير فتح بعملية جراحية أما
+
+106
+00:07:19,750 --> 00:07:22,870
+في التانية العليا الصالة أنا بقترق الجلد بدون
+
+107
+00:07:22,870 --> 00:07:28,130
+مفتاح ال testis و هنشوف كيف العملية بيهتم نجي
+
+108
+00:07:28,130 --> 00:07:33,690
+للمرة الأولى أو المصطلح الأول اللي سمته مي سا و بي
+
+109
+00:07:33,690 --> 00:07:38,490
+سا ال procedure to collect this step او this
+
+110
+00:07:38,490 --> 00:07:42,260
+method we used itأو الـ procedure for this method
+
+111
+00:07:42,260 --> 00:07:47,040
+we can use it to collect sperm from Epidermis عن
+
+112
+00:07:47,040 --> 00:07:50,860
+طريق الـ MESA و الـ PESA يعني الـ Epidermis أنا
+
+113
+00:07:50,860 --> 00:07:54,760
+بجمع منه spermatozoa كتكنولوجيس باستخدام طريقتين
+
+114
+00:07:54,760 --> 00:08:03,560
+طريقة بسميها MESA و PESA طريقة الأولى فيها فتحة
+
+115
+00:08:03,560 --> 00:08:08,360
+بتصير في ال testicularis و الطريقة التانيةبيصير عن
+
+116
+00:08:08,360 --> 00:08:10,440
+طريق الـ aspiration بدخول الـ needle وحنشوفها
+
+117
+00:08:10,440 --> 00:08:15,400
+بالصورة كمان شوية اذا fine needle is used to
+
+118
+00:08:15,400 --> 00:08:22,400
+puncture the epidermis and the epidermal fluid is
+
+119
+00:08:22,400 --> 00:08:27,840
+collected by fine gauge needle aspiration الميسة
+
+120
+00:08:27,840 --> 00:08:31,080
+طبعا هذه لما نقول fine needle بتخترق ال epidermis
+
+121
+00:08:31,080 --> 00:08:37,230
+وبتصير aspiration لل epidermal fluidإذا هدف طالما
+
+122
+00:08:37,230 --> 00:08:40,450
+فيها aspiration بسميها و بدون وجود فتحة جراحية
+
+123
+00:08:40,450 --> 00:08:47,070
+بسميها PSA Aspiration Spam Aspiration في ال MESA
+
+124
+00:08:47,070 --> 00:08:52,170
+بصير فتحة جراحية بسميها Open Surgical Spam
+
+125
+00:08:52,170 --> 00:08:56,350
+Retrovide Procedure that used an operating
+
+126
+00:08:56,350 --> 00:09:01,650
+microscopic to locate the tupule of the epidermis
+
+127
+00:09:01,650 --> 00:09:05,450
+يعني بمعنى أخر أنا بحدد ال epidermis و بعمل فتحة
+
+128
+00:09:05,700 --> 00:09:10,080
+جراحية في الغلاف المحيط بالتستس و بصل إلى ال
+
+129
+00:09:10,080 --> 00:09:13,680
+Epidermis عشان أعمل aspiration لل fluid الموجود
+
+130
+00:09:13,680 --> 00:09:18,520
+منه يعني ما بخترق ال skin و ما بعمل puncture لل
+
+131
+00:09:18,520 --> 00:09:22,120
+skin المحيط بالتستس بفعل needle من الخارج لأن أنا
+
+132
+00:09:22,120 --> 00:09:28,280
+بعمل فتحة جراحية فيها once they are located the
+
+133
+00:09:28,280 --> 00:09:32,540
+tupules are opened and the spermatic fluid that
+
+134
+00:09:32,540 --> 00:09:37,410
+follow out is aspiratedببساطة جدا يعني انا حددت
+
+135
+00:09:37,410 --> 00:09:41,990
+الـ Epidermis عملت فتحة جراحية بمشروط جراحي حددت
+
+136
+00:09:41,990 --> 00:09:45,330
+التيبيول اللي انا بده اسحب منه ال spermatozoa عملت
+
+137
+00:09:45,330 --> 00:09:47,790
+aspiration لل spermatozoa fluid او ال spermatic
+
+138
+00:09:47,790 --> 00:09:53,350
+fluid من منطقة ال Epidermis إذا كلا الطريقتين سواء
+
+139
+00:09:53,350 --> 00:09:57,510
+كانت الميسا أو البيسا بتصير في ال Epidermis
+
+140
+00:09:57,510 --> 00:10:04,720
+aspiration أو ال Epidermislocation او epidermis
+
+141
+00:10:04,720 --> 00:10:09,040
+part ولكن واحدة بتصير micro surgical واحدة بتصير
+
+142
+00:10:09,040 --> 00:10:14,740
+حاجة بتسميها puncture of the skin precontinuous
+
+143
+00:10:14,740 --> 00:10:21,440
+regardless for the approach of epidermal fluid is
+
+144
+00:10:21,440 --> 00:10:24,460
+placed on the petri dish and examined under the
+
+145
+00:10:24,460 --> 00:10:27,710
+microscope in vitro microscopeInverted Microscope
+
+146
+00:10:27,710 --> 00:10:31,610
+to confirm the presence of Motile Sperm سواء أنا
+
+147
+00:10:31,610 --> 00:10:35,850
+جمعت الـ Epidermal Fluid أو أفضل Epidermal Fluid
+
+148
+00:10:35,850 --> 00:10:39,330
+سواء جمعت Epidermal Fluid باستخدام الـ ESA أو الـ
+
+149
+00:10:39,330 --> 00:10:43,850
+PSA هذا ال Epidermal Fluid بوضعه في Petri dish و
+
+150
+00:10:43,850 --> 00:10:47,190
+بفحصه تحت ال Inverted Microscope على عدسة وقوة
+
+151
+00:10:47,190 --> 00:10:51,310
+تكبير 400X و بشوف هل يحتوى على Spermatozoa ولا لأ
+
+152
+00:10:51,310 --> 00:10:56,540
+بشرط أن تكون Motile Spermatozoaإذن هذا الفرق ما
+
+153
+00:10:56,540 --> 00:11:02,860
+بين ال PC و ال MESA ال PC أسبيراشن بشكل مباشر بدون
+
+154
+00:11:02,860 --> 00:11:06,300
+اختراق للجلد لفتحة جراحية أما ال MESA هي
+
+155
+00:11:06,300 --> 00:11:10,040
+Microsurgical أنا بعمل فتحة لفي الجلد طبعا هي أنا
+
+156
+00:11:10,040 --> 00:11:14,060
+شايف أدخل نيدل في الإبددمس مباشرة إذن هذا بسميه
+
+157
+00:11:14,060 --> 00:11:19,000
+Precutaneous Epidermal Sperm Aspirationعمل سكشة لـ
+
+158
+00:11:19,000 --> 00:11:23,580
+spermatozoa لـ spermatozoa او لإبّي dead male
+
+159
+00:11:23,580 --> 00:11:28,440
+fluid حطها
+
+160
+00:11:28,440 --> 00:11:31,400
+في petri dish وشافها تحت الـ inverted microscope
+
+161
+00:11:31,400 --> 00:11:35,600
+هل تحتوي على motile sperm ولا لأ طبعا إذا كانت
+
+162
+00:11:35,600 --> 00:11:39,140
+تحتوي إليها فعل وحدث وإذا كانت لا تحتوي إليها فعل
+
+163
+00:11:39,140 --> 00:11:44,440
+وحدث مغير ومختلف طبعا
+
+164
+00:11:44,440 --> 00:11:46,240
+بعد ما أقيسها
+
+165
+00:11:49,150 --> 00:11:54,650
+والله في sperm كافي ومافيش إذا في sperm كافي
+
+166
+00:11:54,650 --> 00:11:57,950
+مباشرة بعمل sperm washing أو بعمل gradient
+
+167
+00:11:57,950 --> 00:12:01,470
+centrifugation بناء على اللي أنا شو بده أعمل
+
+168
+00:12:01,470 --> 00:12:04,850
+بالعينة و الله إذا بده أعمل بالعينة I و I sperm أو
+
+169
+00:12:04,850 --> 00:12:08,190
+swarm up بتكفي إذا بده أعمل Xيه ال gradient مهم
+
+170
+00:12:08,190 --> 00:12:12,450
+جدا طب تصور إنه مافيش end sperm في العينة بس حتي
+
+171
+00:12:12,450 --> 00:12:17,790
+اللي بيدتمل fluid أو ال fluid الموجودفي الـ
+
+172
+00:12:17,790 --> 00:12:20,350
+Epidermis ما لاجدش فيه أندي كمية كافية من ال
+
+173
+00:12:20,350 --> 00:12:24,970
+spermatozoa إيش بده أعمل ساعتها مباشرة بلجأ إلى ال
+
+174
+00:12:24,970 --> 00:12:28,550
+M مايعرف اسم ال Microscopic Examination طبعا
+
+175
+00:12:28,550 --> 00:12:33,350
+عملتها مالاجدش كمية كافية بلجأ إلى ال MEC وهي
+
+176
+00:12:33,350 --> 00:12:37,750
+عبارة عن فتحة جراحية في الscortum بحدد اللوب الخاص
+
+177
+00:12:37,750 --> 00:12:42,650
+بال Epidermis و بعمل aspiration منه بشكله المباشر
+
+178
+00:12:42,650 --> 00:12:48,470
+والثاني إذا لاجدتالكمية طبعا الكافية و حضرت العينة
+
+179
+00:12:48,470 --> 00:12:51,370
+جزء من العينة بخليها تروح للحفن و الجزء التاني
+
+180
+00:12:51,370 --> 00:12:54,710
+بعملها freezing او ما يُعرف اسم ال
+
+181
+00:12:54,710 --> 00:13:00,110
+cryopreservation للمستقبل تمام؟ هذه الفرق ما بين
+
+182
+00:13:00,110 --> 00:13:06,110
+ال Pc و ال Mc for sperm aspiration or collection
+
+183
+00:13:06,110 --> 00:13:10,930
+from a bed moss خلينا نشوف الفيديو المتعلق بهذه
+
+184
+00:13:10,930 --> 00:13:11,450
+العملية
+
+185
+00:13:36,500 --> 00:13:37,900
+موسيقى
+
+186
+00:14:08,680 --> 00:14:10,080
+موسيقى
+
+187
+00:14:55,100 --> 00:14:57,000
+هو العملية اللي شبهت في الفيديو هي عبارة عن عملية
+
+188
+00:14:57,000 --> 00:15:00,760
+مصغرة تم فتح الجلد المحيط بالـ Testis ثم وصولا إلى
+
+189
+00:15:00,760 --> 00:15:05,360
+ال Epidermis طبعا فتح وعمل جروح في ال Epidermis
+
+190
+00:15:05,360 --> 00:15:08,140
+عشان يخرج السائل الموجود فيه المكازن فيه و بعدين
+
+191
+00:15:08,140 --> 00:15:11,420
+يعمله suction طالما أنا عملت بهذا الشكل و فيه فتحة
+
+192
+00:15:11,420 --> 00:15:15,500
+جراحية بسميها MS micro-surgical لو أنا دخلت ب
+
+193
+00:15:15,500 --> 00:15:18,700
+needle و بس اخترق الجلد عن طريق ال needle بدون
+
+194
+00:15:18,700 --> 00:15:23,040
+فتحة جراحية بسميها PC طبعا المنطق بقول إن أعمل PC
+
+195
+00:15:23,040 --> 00:15:28,660
+في الأول مالاجهش أعملهذه الفكرة الأساسية المتعلقة
+
+196
+00:15:28,660 --> 00:15:35,800
+بهذا الموضوع الطريقة التانية طريقة الـ TSA هي
+
+197
+00:15:35,800 --> 00:15:38,960
+عبارة عن طريقة يتم فيها عمل collection للـ
+
+198
+00:15:38,960 --> 00:15:42,700
+spermatozoa من المصنع مباشرة مش من مكان التخزين من
+
+199
+00:15:42,700 --> 00:15:46,140
+المصنع المباشرة يعني مقصود فيها من الـ testis so
+
+200
+00:15:46,140 --> 00:15:49,160
+the sample spermatozoa should be collected from
+
+201
+00:15:49,160 --> 00:15:53,380
+the testis either by testicular sperm aspirationor
+
+202
+00:15:53,380 --> 00:15:56,280
+testicular sperm extraction لما أقول aspiration
+
+203
+00:15:56,280 --> 00:15:58,980
+يعني أنا باخد fluid لما أقول extraction يعني أنا
+
+204
+00:15:58,980 --> 00:16:04,080
+باخد tissue he say samples are obtained with wide
+
+205
+00:16:04,080 --> 00:16:08,640
+pore needle pushed recontinuously into the testis
+
+206
+00:16:08,640 --> 00:16:11,740
+يعني في عندى needle هذه ال needle ال pores تبعتها
+
+207
+00:16:11,740 --> 00:16:16,760
+عريضة جدا بتتم اختراقها للجلد وصولا إلى ال testis
+
+208
+00:16:16,760 --> 00:16:20,980
+مجرد أنه اتصل لل testis بتتم عمل suction لل fluid
+
+209
+00:16:20,980 --> 00:16:25,830
+الموجود أو لجزءمن .. خلّيني أسأل .. إذا صح التعبير
+
+210
+00:16:25,830 --> 00:16:30,290
+لجزء من الـ tissue عمل suction عن طريق بنزع ال
+
+211
+00:16:30,290 --> 00:16:35,790
+tissue انتزاع بدون اختراق الجلد أنا بدخل needle و
+
+212
+00:16:35,790 --> 00:16:39,210
+ال needle هي اللي بتعمل catching ل ال biopsy أو ال
+
+213
+00:16:39,210 --> 00:16:41,750
+tissue ال testicular tissue و بتعملها عملية
+
+214
+00:16:41,750 --> 00:16:46,890
+extraction أما بالنسبة لل TC بال E لأ أنا بعمل
+
+215
+00:16:46,890 --> 00:16:50,670
+removingOpen technique that removes several pieces
+
+216
+00:16:50,670 --> 00:16:54,530
+of testis tissue بعدين باخد يعني بعمل فتحة جراحية
+
+217
+00:16:54,530 --> 00:16:59,470
+بصل ال testis وباخد منها نسيج اتنين تلاتة من اكتر
+
+218
+00:16:59,470 --> 00:17:04,690
+من منطقة TSA samples are evaluated for motile or
+
+219
+00:17:04,690 --> 00:17:08,210
+immotile spermatozoa with stereo microscope هناخد
+
+220
+00:17:08,210 --> 00:17:10,730
+إيش يعني stereo وإيش يعني inverted microscope
+
+221
+00:17:10,730 --> 00:17:14,940
+العين اللي أخدتها من ال testicular tissueأو
+
+222
+00:17:14,940 --> 00:17:18,400
+testicular biopsy سواء كانت باستخدام الـ TSA أو
+
+223
+00:17:18,400 --> 00:17:22,520
+الـ TSA بعمل إيه ما إلها عملية evaluation باستخدام
+
+224
+00:17:22,520 --> 00:17:26,880
+الـ stereomicroscope و بشوف هل تحتوى على motile أو
+
+225
+00:17:26,880 --> 00:17:30,360
+non motile sperm ولكن خدوا بالك طالما أنا آخر ما
+
+226
+00:17:30,360 --> 00:17:33,960
+أخد tissue لازم هذا ال tissue أقطعه بشكل كبير جدا
+
+227
+00:17:33,960 --> 00:17:37,620
+جدا جدا جدا أقطعه أكثر من مرة عشان يصير انديجيزيات
+
+228
+00:17:37,620 --> 00:17:41,920
+صغيرة جدا جدا جدا تم تسمح بخروج ال spermatozoa
+
+229
+00:17:41,920 --> 00:17:46,240
+اللي تكون محجوزة داخل هذاالـ tissue داخل هذا الـ
+
+230
+00:17:46,240 --> 00:17:51,260
+tissue طبعا هي عند الـ TSA بالـ A طالما بالـ A
+
+231
+00:17:51,260 --> 00:17:54,560
+يعني بعمل aspiration هاي ال needle اللي بتاع ..
+
+232
+00:17:54,560 --> 00:17:58,260
+اللي لها pores very wide دخلت من خلال ال testes
+
+233
+00:17:58,260 --> 00:18:04,920
+اخترقتها وصلت ل testicular عملت ضغط عن طريق high
+
+234
+00:18:04,920 --> 00:18:09,240
+pressure أو high push اخترقت ال TSA وأخدت منها
+
+235
+00:18:09,240 --> 00:18:12,960
+قطعة من النسيج هذه قطعة النسيج الموجودة في ال test
+
+236
+00:18:12,960 --> 00:18:18,240
+tubeبعملها عملية fragmentation أو بسميها عملية
+
+237
+00:18:18,240 --> 00:18:22,680
+section عن طريق ال forceps الحالي بقطعها قطع صغيرة
+
+238
+00:18:22,680 --> 00:18:26,800
+جدا جدا جدا حتى تسمح و بغسلها مرة و اتنين حتى تسمح
+
+239
+00:18:26,800 --> 00:18:30,860
+بخروج طبعا مش بغسلها بضيف عليها المحلول و بكبه لأ
+
+240
+00:18:30,860 --> 00:18:33,840
+ان بضيف عليها المحلول علشان تسمح بخروج ال
+
+241
+00:18:33,840 --> 00:18:39,250
+spermatozoa و بشوف هذا النسيج تحت ال microscopeبعد
+
+242
+00:18:39,250 --> 00:18:42,130
+كده بعملها عملية centrifugation عشان يتخلص من كل
+
+243
+00:18:42,130 --> 00:18:46,230
+fluid و ما يتخلص من كل ال tissue و يبقى ال fluid
+
+244
+00:18:46,230 --> 00:18:49,930
+اللي يحتوي على ال spermatozoon بعملها evaluation
+
+245
+00:18:49,930 --> 00:18:55,910
+فيما بعد طيب إذا عملت ال aspiration أو تسأل P سا
+
+246
+00:18:55,910 --> 00:18:59,350
+بالA aspiration و لجيت في عندك كمية كافية من ال
+
+247
+00:18:59,350 --> 00:19:04,250
+spermatozoon تحت ال inverted microscope ببدأ
+
+248
+00:19:04,250 --> 00:19:09,220
+أحضرهالعملية الحقن المجهوري من خلال الـ Density
+
+249
+00:19:09,220 --> 00:19:12,960
+Gradient Centrifugation و ببعتها للمختبر إذا كانت
+
+250
+00:19:12,960 --> 00:19:16,360
+العينة كافية و جزء منها بخزنه إذا كانت العينة لا
+
+251
+00:19:16,360 --> 00:19:20,720
+تحتوى على كمية كافية من الـ sperm metazoa تصلح
+
+252
+00:19:20,720 --> 00:19:25,000
+للإكزي يعني adequated sample for sperm for إكزي is
+
+253
+00:19:25,000 --> 00:19:28,660
+not enough بروح بعمل موضوع تاني وهو عبارة عن الـ
+
+254
+00:19:28,660 --> 00:19:34,230
+TC بالـ E وهو أنا باخد tissueمرة و مرتين و تلاتة
+
+255
+00:19:34,230 --> 00:19:39,610
+باستخدام micro operation .. micro surgical
+
+256
+00:19:39,610 --> 00:19:43,870
+operation في منطقة ال testis و باخد النسيج من اكثر
+
+257
+00:19:43,870 --> 00:19:48,370
+من منطقة من one side سواء كانت ال left او ال right
+
+258
+00:19:48,370 --> 00:19:52,970
+testis left او ال right testis خلينا نشوف الكلام
+
+259
+00:19:52,970 --> 00:19:57,970
+اللي كلمنا عنه و اللي متعلق بال TC او ال TC
+
+260
+00:20:12,620 --> 00:20:14,020
+أمريكا
+
+261
+00:20:22,830 --> 00:20:26,590
+طب نخدوا بالكوا هنا عمل فتحة جراحية في منطقة ال
+
+262
+00:20:26,590 --> 00:20:30,750
+testis وصل إلى الأنسجة المخلقة ال spermatozoa و
+
+263
+00:20:30,750 --> 00:20:33,770
+بدأ ياخد بيبس منها عن طريق عملية الانتزاع فهذه
+
+264
+00:20:33,770 --> 00:20:40,470
+عبارة عن TESE وليس TESE مافيها aspiration لأنه عمل
+
+265
+00:20:40,470 --> 00:20:43,190
+extraction ل testicular tissue
+
+266
+00:21:07,000 --> 00:21:08,400
+موسيقى
+
+267
+00:21:47,680 --> 00:21:50,640
+طبعا هنا بتكلم كيف بدي أعمل ال processing لعينة ال
+
+268
+00:21:50,640 --> 00:21:53,800
+testicular tissue في عينة محاضرة وشكتر كامل اللي
+
+269
+00:21:53,800 --> 00:21:57,520
+علاقة بال sample processing وكيف أنا بدي أعمل ال
+
+270
+00:21:57,520 --> 00:22:02,360
+spermatozoa تحت الميكروسكوب وفي عملية ال exudation
+
+271
+00:22:02,360 --> 00:22:02,780
+preparation
+
+272
+00:22:28,870 --> 00:22:33,070
+طبعا هذه العملية المتعلقة بالـ Tc بالـ A والـ Tc
+
+273
+00:22:33,070 --> 00:22:37,170
+بالـ E و الفرق ما بينهم و كيف أخد عينة الـ
+
+274
+00:22:37,170 --> 00:22:41,970
+testicular fluid و testicular tissue أيضا في حالة
+
+275
+00:22:41,970 --> 00:22:45,640
+ال micro operationوكيف بدأ يفحصها تحت ال inverted
+
+276
+00:22:45,640 --> 00:22:49,800
+microscope و ال stereo microscope علشان يتأكد فيها
+
+277
+00:22:49,800 --> 00:22:54,920
+spermatozoa ولا لأ هذه الفكرة ال testicular tissue
+
+278
+00:22:54,920 --> 00:23:00,020
+او ال epidermis fluid aspiration في حالة ال
+
+279
+00:23:00,020 --> 00:23:02,960
+obstructive و ال non-obstructive azosperma طب لو
+
+280
+00:23:02,960 --> 00:23:06,540
+انا قرنت بينهم على سبيل المثال بيسا بدها local
+
+281
+00:23:06,540 --> 00:23:11,850
+anesthesia يعني انك ك male يخضر تخضير موضعيفإنما
+
+282
+00:23:11,850 --> 00:23:17,190
+في الميسا في عملية جراحية تخضير كلي نسبة الحصول
+
+283
+00:23:17,190 --> 00:23:23,230
+على ال sperm 80% إلى 100% في الطريقة الأولى من 95%
+
+284
+00:23:23,230 --> 00:23:27,510
+إلى 100% في الطريقة التانية طبعا في الها
+
+285
+00:23:27,510 --> 00:23:33,410
+disadvantage مافي طريقة صحية وسليمة 100% كلها
+
+286
+00:23:33,410 --> 00:23:36,150
+advantage لأ في disadvantage فالطريقة الأولى
+
+287
+00:23:36,150 --> 00:23:41,350
+disadvantage هيماتوما بيظهر عندىفي فرصة للمحصولة
+
+288
+00:23:41,350 --> 00:23:44,590
+على كمية كافية من الـ spermatozoa بالإضافة إلى can
+
+289
+00:23:44,590 --> 00:23:48,990
+induce epidermal obstruction ممكن يبدأ لها أما
+
+290
+00:23:48,990 --> 00:23:52,510
+الميسا required operation room and micro surgical
+
+291
+00:23:52,510 --> 00:23:55,710
+scale يعني عملية جراحية حتى لو كانت عملية جراحية
+
+292
+00:23:55,710 --> 00:24:01,770
+صغيرة لو أنا قرنت ما بين ال Tc و Tc طبعا الأولى
+
+293
+00:24:01,770 --> 00:24:04,810
+طالما aspiration local واناستيزيا التانية طالما
+
+294
+00:24:04,810 --> 00:24:08,660
+operation generalالكمية الـ spermatozoa التي يمكن
+
+295
+00:24:08,660 --> 00:24:12,520
+أن نحصل عليها بالطريقة الأولى 52% إلا 100% أما
+
+296
+00:24:12,520 --> 00:24:15,800
+الطريقة التانية 100% عشان كده اللي هتبقى بالجائلة
+
+297
+00:24:15,800 --> 00:24:20,540
+بشكل عام ولكن مشكلتها أنها very painful شغلة تانية
+
+298
+00:24:20,540 --> 00:24:23,820
+أن النسيج اللي بتاخده مايرجع بيه المتاني بيصير
+
+299
+00:24:23,820 --> 00:24:26,800
+تليف في هذا المنطقة يعني كأنه منطقة بتموت
+
+300
+00:24:26,800 --> 00:24:31,320
+disadvantage hematomaكمية قليلة جدا من الـ
+
+301
+00:24:31,320 --> 00:24:33,800
+spermatosis و ممكن نحصل عليها بالطريقة الأولى أما
+
+302
+00:24:33,800 --> 00:24:37,360
+الطريقة التانية ال risk of testicular atrophy and
+
+303
+00:24:37,360 --> 00:24:40,320
+hypo functional في عند ال risk أنه يصير عندي hypo
+
+304
+00:24:40,320 --> 00:24:44,360
+functional في ال testis تحتاج إلى غرفة جراحية،
+
+305
+00:24:44,360 --> 00:24:48,880
+تحتاج إلى معدات، تحتاج إلى اهتمام بشكل كبير جدا
+
+306
+00:24:48,880 --> 00:24:54,500
+جدا جدا خلال عملية الاستشفاء خلال عملية الاستشفاء
+
+307
+00:24:55,960 --> 00:24:58,860
+طبعاً الـ spermatozoa حصلنا عليها باستخدام
+
+308
+00:24:58,860 --> 00:25:02,640
+testicular biopsy، كيف نتأكد أن هذا الحيوان المنوي
+
+309
+00:25:02,640 --> 00:25:06,640
+اللي حصلنا عليه حي؟ لأن عملية الحقن يجب أن تحدث
+
+310
+00:25:06,640 --> 00:25:10,600
+باستخدام life spermatozoa، مش أي حيوان منوي أنا
+
+311
+00:25:10,600 --> 00:25:13,970
+باستخدمه في عملية الحقنلازم يكون أقل شيء live
+
+312
+00:25:13,970 --> 00:25:19,610
+فممكن أنا أفحصه باستخدام فحص بتسميه hypo osmotic
+
+313
+00:25:19,610 --> 00:25:22,630
+swelling test اللي سمته host test واتكلمنا عنه في
+
+314
+00:25:22,630 --> 00:25:26,790
+المرحلة السابقة إن أنا بضيف ال spermatozoa اللي
+
+315
+00:25:26,790 --> 00:25:30,410
+أنا طلعتها فيه محلولهو عبارة عن hypotonic solution
+
+316
+00:25:30,410 --> 00:25:34,170
+وبشوف ال tail الخاص بهذا ال sperm صاله swelling
+
+317
+00:25:34,170 --> 00:25:37,070
+ولا لأ والله إذا صاله swelling ال end of tail
+
+318
+00:25:37,070 --> 00:25:40,690
+معناه هذا ال sperm متزوه استجاب واتفاعل مع المحلول
+
+319
+00:25:40,690 --> 00:25:44,970
+إذا هذا ال sperm متزوه أو ال sperm حي يمكن أن
+
+320
+00:25:44,970 --> 00:25:50,850
+يستخدم ومهم جدا أنه يتم غسل ال sperm الحي بعد
+
+321
+00:25:50,850 --> 00:25:54,930
+تعريضه لل hypo osmotic solution ب fresh mediaعلشان
+
+322
+00:25:54,930 --> 00:25:59,550
+يتخلص من المحلول اللي دخل على هذا ال sperm هذه
+
+323
+00:25:59,550 --> 00:26:05,810
+العملية فقط بتحتاج إلى 20 دقيقة ثانية على حد أعلى
+
+324
+00:26:05,810 --> 00:26:10,510
+أثناء استخدام وفحص ال spermatozoon هل هو حي أم لأ
+
+325
+00:26:10,510 --> 00:26:15,710
+من أجل إخضاعه وإشراكه في عملية الحقن الميجاري هذه
+
+326
+00:26:15,710 --> 00:26:19,890
+الشكل اللي بقصود فيه تلاقي ال sperm في عنده هذا ال
+
+327
+00:26:19,890 --> 00:26:22,630
+sperm dead هذا ال sperm اللي في نهاية التل فيه
+
+328
+00:26:22,630 --> 00:26:27,260
+عنده انتفارأو انتفاخ معناه أن الـ sperm حي يصلح أن
+
+329
+00:26:27,260 --> 00:26:31,360
+يستخدم في عملية الحقن الميجاري في طريقة تانية
+
+330
+00:26:31,360 --> 00:26:35,400
+طريقة ال sperm tail flexibility test ان انا بشوف
+
+331
+00:26:35,400 --> 00:26:38,980
+هل ال sperm flexible ولا مش flexible كيف انا بده
+
+332
+00:26:38,980 --> 00:26:43,860
+اقيصه لبساطة جدا ان using micro injection pipette
+
+333
+00:26:44,520 --> 00:26:48,680
+up morphological normal in motile sperm from sperm
+
+334
+00:26:48,680 --> 00:26:52,400
+micro drop and transferred to the PPV solution
+
+335
+00:26:52,400 --> 00:26:57,120
+يعني تحت الميكروسكوب أي sperm مش متحرك ولكن
+
+336
+00:26:57,120 --> 00:27:01,040
+morphological normal بسحبه وبنقله لقطرة جديدة
+
+337
+00:27:01,040 --> 00:27:05,320
+بنقله لبتردش جديد بنقله لبتردش يحتوي على media
+
+338
+00:27:05,320 --> 00:27:09,180
+بسميها PVP media خدوا بالكوا من هذه ال media
+
+339
+00:27:09,180 --> 00:27:13,420
+هنتكلم عنها بشكل مستفيد شو هي ال media وشو أهميتها
+
+340
+00:27:14,360 --> 00:27:17,860
+ببساطة جدا مش هنتكلم عنها اليوم ولكن من أحد
+
+341
+00:27:17,860 --> 00:27:21,760
+أهميتها أن تبقى طبق الحيوان المنوي في ظروف طبيعية
+
+342
+00:27:21,760 --> 00:27:25,620
+هنتكلم اللي هي وظائف أخرى اللي هي علاقة بطريقة
+
+343
+00:27:25,620 --> 00:27:30,300
+التعامل وإخفاء حركة الحيوان المنوي ولكن ببساطة
+
+344
+00:27:30,300 --> 00:27:33,460
+شوفت هذا الحيوان المنوي normal form ولكن non
+
+345
+00:27:33,460 --> 00:27:36,540
+-mutation بعمله aspiration و بلقله في petri dish
+
+346
+00:27:36,540 --> 00:27:42,840
+يحتوي على ميديا اسم PVP Media بعد كده باجي بطرف ال
+
+347
+00:27:42,840 --> 00:27:47,740
+injection needleبعمل touching للـ sperm with the
+
+348
+00:27:47,740 --> 00:27:50,940
+tip of micro injection pipet and forces the tail
+
+349
+00:27:50,940 --> 00:27:55,320
+to move up and down يعني بمعنى أخر باجي في نهاية
+
+350
+00:27:55,320 --> 00:28:00,160
+الـ tail الخاص بالـ sperm بدفع الـ sperm للأعلى أو
+
+351
+00:28:00,160 --> 00:28:05,160
+بدفع للأسفل وبشوف هل الـ sperm الـ tail الخاص بالـ
+
+352
+00:28:05,160 --> 00:28:08,660
+sperm فيه رد فعل ولا لا tail is considered
+
+353
+00:28:08,660 --> 00:28:12,020
+flexible when it moves independent of sperm head
+
+354
+00:28:12,530 --> 00:28:16,210
+بمعنى آخر إذا كان الـ sperm flexible الـ tail
+
+355
+00:28:16,210 --> 00:28:20,730
+الخاص بالـ sperm flexible هلاجي أن الـ head بتحرك
+
+356
+00:28:20,730 --> 00:28:24,430
+في اتجاه و الـ tail بتحرك في اتجاه آخر يعني بمعنى
+
+357
+00:28:24,430 --> 00:28:28,730
+آخر حركة الـ they لا تعتمد على حركة الـ head يعني
+
+358
+00:28:28,730 --> 00:28:33,050
+منفصلين منفصلين so sperm tail flexible is
+
+359
+00:28:33,050 --> 00:28:35,930
+considered a marker or indicator of sperm
+
+360
+00:28:35,930 --> 00:28:40,010
+viability إذا والله أنا أخدت هذا الـ sperm أتزوه
+
+361
+00:28:40,460 --> 00:28:43,860
+وحطته في طبق تحتوي على ال pvp media وجبت ال
+
+362
+00:28:43,860 --> 00:28:47,660
+injection needle وحركت نهاية ال sperm tail ولاجيت
+
+363
+00:28:47,660 --> 00:28:51,480
+أن ال sperm بتحرك في جهة و ال head بتحرك في جهة
+
+364
+00:28:51,480 --> 00:28:56,600
+معناه هذا أن ال sperm flexible ال tail لهذا ال
+
+365
+00:28:56,600 --> 00:29:01,860
+sperm flexible معناه أن ال sperm هذا حي الله يصلح
+
+366
+00:29:01,860 --> 00:29:05,640
+عملية الحقن المجاني والله لو انا حركته ولاجيت ال
+
+367
+00:29:05,640 --> 00:29:10,040
+tail و ال head بتحركوا مع بعض في اتجاه واحدمعناه
+
+368
+00:29:10,040 --> 00:29:14,080
+إن هذا الـ sperm non-flexibility دبعته equal zero
+
+369
+00:29:14,080 --> 00:29:18,240
+فلا يمكن أن يستخدم في الحقن المجاري if the tail
+
+370
+00:29:18,240 --> 00:29:21,860
+remain bridge upon touching and sperm head and
+
+371
+00:29:21,860 --> 00:29:25,940
+tail move together as one unit this sperm .. the
+
+372
+00:29:25,940 --> 00:29:28,680
+flexibility of this sperm equal zero and we cannot
+
+373
+00:29:28,680 --> 00:29:35,400
+be used for exit إذن الديل والديل بعد عملية اللمس
+
+374
+00:29:35,400 --> 00:29:39,270
+باستخدام ال injection needleتحرك بشكل مستقل عن
+
+375
+00:29:39,270 --> 00:29:42,550
+الهد يعني كلاهم في اتجاه المختلفين إذا هذا الحيوان
+
+376
+00:29:42,550 --> 00:29:47,430
+المنوي حي يمكن استخدامه الذير والهد تحركوا كقطلة
+
+377
+00:29:47,430 --> 00:29:50,790
+واحدة واحدة واحدة في اتجاه واحد إذا لا يمكن
+
+378
+00:29:50,790 --> 00:29:57,710
+استخدامه في عملية الحقن هذا ما يتعلق بمحاضرة اليوم
+
+379
+00:29:57,710 --> 00:30:01,770
+كيف يمكن الحصول على ال spermatozoa باستخدام ال
+
+380
+00:30:01,770 --> 00:30:05,770
+testicular biopsy بالأنواع الثلاثة المختلفة كيف
+
+381
+00:30:06,160 --> 00:30:11,540
+يمكن فحص الحيوان المنوي بعد ما أنا أحضره و أستخلصه
+
+382
+00:30:11,540 --> 00:30:15,340
+من النسيج هل هو mutile ولا non-mutile واللي أهم من
+
+383
+00:30:15,340 --> 00:30:19,000
+كده هل هو life ولا non-life ولا non-life or dead
+
+384
+00:30:19,000 --> 00:30:23,540
+sperm لأنه مهم جدا أن أعمل عملية الحقن باستخدام
+
+385
+00:30:23,540 --> 00:30:29,420
+life sperm, no dead sperm we cannot be used dead
+
+386
+00:30:29,420 --> 00:30:34,950
+sperm during IGZ or in IGZ processفممكن أنا بعد ال
+
+387
+00:30:34,950 --> 00:30:38,210
+testicular biopsy ألاقي كل الحيوانات المنوية non
+
+388
+00:30:38,210 --> 00:30:42,790
+-motile ما أفقد الثقة و أفقد الفرصة بقول ممكن يكون
+
+389
+00:30:42,790 --> 00:30:47,350
+non-motile ولكنه life فبأخد هذه ال normal form non
+
+390
+00:30:47,350 --> 00:30:51,250
+-motile spermatozoa و بعرضها لل hypotonic solution
+
+391
+00:30:51,250 --> 00:30:54,850
+أو بعملها flexibility test و أشوف هل ال sperm tail
+
+392
+00:30:54,850 --> 00:30:59,590
+بتحرك في اتجاه ال head tail كوحدة واحدة أو في
+
+393
+00:30:59,590 --> 00:31:02,490
+اتجاهين مختلفينإذا كانوا في اتجاهين مختلفين is a
+
+394
+00:31:02,490 --> 00:31:05,950
+life sphere, we can use it during or exit process
+
+395
+00:31:05,950 --> 00:31:09,370
+or exit operation إذا كانوا بتحركوا كوحدة واحدة لا
+
+396
+00:31:09,370 --> 00:31:12,970
+يمكن استخدامه يكفي في هذا القدر من المعلومات في
+
+397
+00:31:12,970 --> 00:31:17,630
+هذه المحاضرة على أمل أن نلتقي دائما بخير وعلى خير
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/OQJTimakS2c.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/OQJTimakS2c.srt
new file mode 100644
index 0000000000000000000000000000000000000000..ece40b1b5ef393f3aaa83023b799aa14e68c70c5
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/OQJTimakS2c.srt
@@ -0,0 +1,1339 @@
+1
+00:00:01,030 --> 00:00:04,750
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:04,750 --> 00:00:10,130
+المرسلين سيدنا محمد الصادق الأمين  أما بعد بداية
+
+3
+00:00:10,130 --> 00:00:14,070
+نرحب بكم طلبة الماجستير في قسم العلوم الطبية
+
+4
+00:00:14,070 --> 00:00:21,050
+المخبرية كلية العلوم الصحية والمسجلين لمساق مواضيع 
+
+5
+00:00:21,050 --> 00:00:26,130
+خاصة في العلوم الطبية المخبرية سأكون معكم أنا
+
+6
+00:00:26,130 --> 00:00:33,250
+الدكتور محمد ماروان مرقان، حصل على درجة الدكتوراه من
+
+7
+00:00:33,250 --> 00:00:37,790
+جامعة Saarland ألمانيا في تخصص molecular biology
+
+8
+00:00:37,790 --> 00:00:43,450
+and biochemistry of reproductive medicine طبعاً
+
+9
+00:00:43,450 --> 00:00:48,690
+هذا الـ course هيتناول بشكل أساسي مصطلح الـ IVF
+
+10
+00:00:48,690 --> 00:00:53,990
+مصطلح الإكزي وهو عبارة عن مصطلح قد يكون سمع به
+
+11
+00:00:53,990 --> 00:01:00,420
+البعض والبعض الآخر قرأ عنه في مكان، طبعاً، بدايةً،
+
+12
+00:01:00,420 --> 00:01:04,540
+مصطلح الـ ICSI معناه الحقن المجهري وهو اختصار للـ 
+
+13
+00:01:04,540 --> 00:01:09,060
+Intracytoplasmic injection ومصطلح الـ IVF هو مصطلح
+
+14
+00:01:09,060 --> 00:01:13,680
+In vitro fertilization أي التلقيح خارج الرحم
+
+15
+00:01:13,680 --> 00:01:19,120
+هنتكلم عن بعض الأمور التي سنتناولها خلال هذا
+
+16
+00:01:19,120 --> 00:01:23,600
+المساق سنتكلم عن الواجبات وعن واجبات الطالب
+
+17
+00:01:23,600 --> 00:01:29,180
+وواجبات المدرس وننطلق في هذه المحاضرة إن شاء الله
+
+18
+00:01:29,180 --> 00:01:34,920
+أهم المواضيع التي سنتكلم عنها موضوع له علاقة مهمة
+
+19
+00:01:34,920 --> 00:01:39,600
+جداً وخاصة في وضعنا الحالي ومجتمعنا الغزاوي موضوع
+
+20
+00:01:39,600 --> 00:01:43,540
+الـ infertility ما هو أو ما هي مشكلة الـ infertility 
+
+21
+00:01:43,540 --> 00:01:47,020
+وهل المقصود بالـ infertility تأخر الإنجاب، عدم
+
+22
+00:01:47,020 --> 00:01:51,080
+الإنجاب، عدم القدرة على الإنجاب أو العقوبة هذي
+
+23
+00:01:51,080 --> 00:01:54,500
+المقصود أو ما هي الـ infertility احنا نتكلم عنها،
+
+24
+00:01:54,500 --> 00:01:59,430
+عن مشاكلها، عن أسبابها، عن تعريفاتها، ثم سوف ننتقل
+
+25
+00:01:59,430 --> 00:02:02,510
+إلى التكلم عن الـ Male and Female gamete ما هي
+
+26
+00:02:02,510 --> 00:02:06,530
+جاميطات الأنثى وما هي جاميطات الذكر كيف تخلق جاميطات
+
+27
+00:02:06,530 --> 00:02:10,210
+الأنثى بين جُثَيْن البويضات وكيف تخلق جاميطات الذكر
+
+28
+00:02:10,210 --> 00:02:15,390
+بين جُثَيْن الـ sperm وكيف تنقل من مصنع التخليق إلى
+
+29
+00:02:15,390 --> 00:02:19,770
+مكان التخزين وكيف تنقل من مكان التخزين إلى مكان الـ
+
+30
+00:02:19,770 --> 00:02:22,690
+fertilization الـ fertilization المقصود فيها عملية
+
+31
+00:02:22,690 --> 00:02:27,460
+الإخصاب بحد ذاتها، ثم سوف ننتقل إلى موضوع جديد وهو
+
+32
+00:02:27,460 --> 00:02:30,960
+الـ Stimulation Protocol at Cultural Media كيف يتم
+
+33
+00:02:30,960 --> 00:02:34,960
+تحفيز مبيض السيدة للوصول إلى عدد كبير جدا من
+
+34
+00:02:34,960 --> 00:02:38,540
+البويضات؟ وما هي أنواع البروتوكولات التي قد
+
+35
+00:02:38,540 --> 00:02:43,040
+تستخدم؟ وما هي مدتها؟ وكيف يمكن تحديد نوع
+
+36
+00:02:43,040 --> 00:02:47,320
+البروتوكول؟ البروتوكول هل يحدد جزافا، عشوائيا،
+
+37
+00:02:47,320 --> 00:02:51,240
+بناء على الأقواء، بناء على المصالح المادية أم هناك
+
+38
+00:02:51,240 --> 00:02:56,320
+أسس معينة بناء عليها يحدد البروتوكول؟ الـ culture
+
+39
+00:02:56,320 --> 00:03:00,460
+media هي عبارة عن الأوساط الزراعية التي تنمى وينمى
+
+40
+00:03:00,460 --> 00:03:04,480
+فيها الـ embryo تقريباً زي الناس اللي بتشتغل في الـ
+
+41
+00:03:04,480 --> 00:03:07,940
+microbiology بتزرع بكتيريا على طبق هذا الطبق هو
+
+42
+00:03:07,940 --> 00:03:12,360
+culture media يسمح بانقسام البكتيريا وفي الـ IVF أو 
+
+43
+00:03:12,360 --> 00:03:18,880
+الـ ICSI نستخدم طبق تحتوي على media تسمح بانقسام الـ
+
+44
+00:03:18,880 --> 00:03:23,610
+embryo للوصول إلى عدد معين من الخلايا، ننتقل فيما
+
+45
+00:03:23,610 --> 00:03:26,250
+بعد إلى حاجة نسميها الـ sperm assessment and
+
+46
+00:03:26,250 --> 00:03:30,570
+processing selection كيف نعمل seminal analysis كيف
+
+47
+00:03:30,570 --> 00:03:33,230
+يتم عمل processing و purification للـ seminal
+
+48
+00:03:33,230 --> 00:03:36,410
+fluid كيف يتم اختيار الحيوان المنوي و الـ single
+
+49
+00:03:36,410 --> 00:03:41,130
+sperm من أجل عملية الحقن ثم سننتقل إلى عملية الحقن
+
+50
+00:03:41,130 --> 00:03:45,790
+بحد ذاتها وهي مصطلح ICSI اسمها الكامل
+
+51
+00:03:45,790 --> 00:03:50,250
+Intracytoplasmic sperm injection Intracytoplasmic
+
+52
+00:03:50,250 --> 00:03:53,170
+sperm injection ثم ننتقل إلى الـ Embryo
+
+53
+00:03:53,170 --> 00:03:56,490
+implantation and embryo biopsy كيف يتم إعادة
+
+54
+00:03:56,490 --> 00:04:01,590
+الجنين بعد عملية انقسامه في المختبر إلى رحم الأنثى
+
+55
+00:04:01,590 --> 00:04:07,010
+ورحم السيدة وكيف نحصل على جنين كامل ثم كيف يتم
+
+56
+00:04:07,010 --> 00:04:11,090
+تشخيص الجنين قبل عملية الإرجاع لأن في بعض العائلات
+
+57
+00:04:11,090 --> 00:04:15,330
+عندهم genetic disease تنتقل من generation لآخر
+
+58
+00:04:15,330 --> 00:04:19,190
+فبحاول أمنع انتقال هذا الـ genetic disease من
+
+59
+00:04:19,190 --> 00:04:23,170
+الأباء إلى الأبناء من خلال فحص الجنين قبل عملية
+
+60
+00:04:23,170 --> 00:04:28,050
+إرجاعه بمصطلح embryobiopsy أو مصطلح آخر PGD
+
+61
+00:04:28,050 --> 00:04:33,130
+Preimplantation Genetic Diagnosis البيوبسي هي أخذ
+
+62
+00:04:33,130 --> 00:04:37,550
+مخزعة من الجنين نفسه إذا كان الجنين 16 خلية بأخد
+
+63
+00:04:37,550 --> 00:04:41,710
+خلية مثلاً ثم ننتقل إلى موضوع جديد وهو الـ
+
+64
+00:04:41,710 --> 00:04:46,590
+cryopreservation كيف يتم الحفاظ على الأجنة الزائدة
+
+65
+00:04:46,590 --> 00:04:50,860
+أو البويضات الزائدة أو الحيوانات المنوية كيف يتم
+
+66
+00:04:50,860 --> 00:04:55,260
+تجميدها، مصطلح معناه التجميد ويعبر عن عملية
+
+67
+00:04:55,260 --> 00:04:59,480
+باختصار يتم فيها تخزين البويضات أو الأجنة في الـ
+
+68
+00:04:59,480 --> 00:05:03,680
+liquid nitrogen الذي تصل درجة حرارته إلى minus
+
+69
+00:05:03,680 --> 00:05:09,260
+سالب 196 درجة مئوية، إن كانت تبقى لدينا وقت سوف
+
+70
+00:05:09,260 --> 00:05:12,840
+نتكلم عن الـ IVF equipment lab equipment ما هي
+
+71
+00:05:12,840 --> 00:05:17,160
+الأجهزة ما هي الأدوات التي يجب وينبغي أن تتواجد في
+
+72
+00:05:17,160 --> 00:05:21,600
+مختبر التلقيح الصناعي طبعاً المواضيع كثيرة مش
+
+73
+00:05:21,600 --> 00:05:25,660
+هأتناولها كلها بناء على الوقت لأن أنا بهمني الـ كيف
+
+74
+00:05:25,660 --> 00:05:30,020
+ولا أهتم بالكم، بهمني الطالب يطلع فاهم بكمية كبيرة
+
+75
+00:05:30,020 --> 00:05:34,140
+جداً لمعلومات المطلوبة، مطلب منكم الـ PowerPoint
+
+76
+00:05:34,140 --> 00:05:36,980
+lecture بشكل أساسي الـ PowerPoint lecture اللي
+
+77
+00:05:36,980 --> 00:05:40,420
+هتنزل على الـ Moodle بشكل مستمر كل يوم ثلاثاء هي
+
+78
+00:05:40,420 --> 00:05:46,780
+المطلوبين فيها فقط لا غير، الكتب المذكورة للاستذكار
+
+79
+00:05:46,780 --> 00:05:50,460
+والاستذكار مثلاً في عند الـ Human Embryology وفي
+
+80
+00:05:50,460 --> 00:05:53,520
+عند In Vitro Fertilization وهو عبارة عن أحدث كتب
+
+81
+00:05:53,520 --> 00:05:58,640
+إلى حد ما في طبع جديدة منهم في 2019 ولكن بطول
+
+82
+00:05:58,640 --> 00:06:04,280
+الكتب هو ما تم اعتماد عليهم عليها من أجل إنتاج هذه
+
+83
+00:06:04,280 --> 00:06:10,260
+المحاضرة طبعاً الـ grading و الـ evaluation الخاصة في
+
+84
+00:06:10,260 --> 00:06:14,990
+الـ course تعتمد على ثلاث مراحل، المرحلة الأولى هي الـ
+
+85
+00:06:14,990 --> 00:06:17,810
+quizzes و الـ homework طبعاً الـ attendance إن رجعنا
+
+86
+00:06:17,810 --> 00:06:22,430
+للتعليم الوجاهي ممكن يكون فيه حضور غياب وخلاله
+
+87
+00:06:22,430 --> 00:06:26,910
+ولكن حيكون فيه end quiz و homework بمعدل 30 درجة طبعاً
+
+88
+00:06:26,910 --> 00:06:30,390
+الـ quizzes هنحدد أوقات معينة بتاريخ معين عشان يعرف
+
+89
+00:06:30,390 --> 00:06:33,330
+الطالب إن والله في اليوم الفلاني هيكون عنده quiz 
+
+90
+00:06:33,330 --> 00:06:37,990
+بالإضافة إلى الـ chapter اللي المفروض يكون فيه الـ
+
+91
+00:06:37,990 --> 00:06:42,430
+quiz مش هنخالف عن الموضوع، ثم بعد ذلك هيكون في end
+
+92
+00:06:42,430 --> 00:06:46,770
+presentation وهي seminar بسيط كل طالبة من الطالبات
+
+93
+00:06:46,770 --> 00:06:51,130
+المسجلين في هذا الـ course هتختار عنوان معين له
+
+94
+00:06:51,130 --> 00:06:53,510
+علاقة بالـ male infertility له علاقة بالـ female
+
+95
+00:06:53,510 --> 00:06:57,710
+infertility له علاقة بالـ diagnostic genetic أي شيء
+
+96
+00:06:57,710 --> 00:07:01,150
+أو أي موضوع له علاقة بالـ IVF أو الـ ICSI بشكل عام
+
+97
+00:07:01,150 --> 00:07:06,930
+هتعمل عليه presentation لمدة 20 دقيقة وتسجله زي
+
+98
+00:07:06,930 --> 00:07:11,250
+ما أنا بسجل صوت مع صورة لسطح المكتب وهي بتشرح هذا
+
+99
+00:07:11,250 --> 00:07:14,950
+الموضوع وترسله على الـ Moodle هيكون في الـ Moodle
+
+100
+00:07:14,950 --> 00:07:17,010
+أيقونة اللي هي علاقة بالـ seminar أو الـ
+
+101
+00:07:17,010 --> 00:07:21,230
+presentation ووقته هنحدده هيكون وقته مفتوح هيكون
+
+102
+00:07:21,230 --> 00:07:26,950
+معكم شهرين ثلاثة ترسله في الـ seminar ثم سوف يكون
+
+103
+00:07:26,950 --> 00:07:30,130
+في النهاية الـ final exam وعليه 60 درجة وهذا طبعاً
+
+104
+00:07:30,130 --> 00:07:33,670
+الـ quiz و الـ final exam كله هيكون إلكتروني ما لم
+
+105
+00:07:33,670 --> 00:07:36,250
+يحدث أي جديد يعني ممكن في لحظة اللي عصابي أقوله
+
+106
+00:07:36,250 --> 00:07:41,650
+رجعنا للتعليم الوجاهي على طر يكون ورقي هذا المقصود
+
+107
+00:07:41,650 --> 00:07:45,170
+في عملية الـ evaluation الخاصة بالطالب وعلشان تتم
+
+108
+00:07:45,170 --> 00:07:49,590
+عملية الـ evaluation والمتابعة بشكل سليم أرجو من
+
+109
+00:07:49,590 --> 00:07:54,030
+أحد الطالبات عمل مجموعة WhatsApp أو مجموعة
+
+110
+00:07:54,030 --> 00:07:57,110
+Facebook whatever اللي بتتلاقوه مناسب بالنسبة لكم
+
+111
+00:07:57,110 --> 00:08:02,250
+تحت عنوان IVF courses for example وإضافة للطالبات
+
+112
+00:08:02,250 --> 00:08:06,580
+زميلاتها عليه بالإضافة إلى إضافتي وإشعار إياد بالأمر
+
+113
+00:08:06,580 --> 00:08:10,400
+علشان يتم متابعة بشكل مستمر وإنزال إعلانات على هذه
+
+114
+00:08:10,400 --> 00:08:14,940
+المجموعة إن شاء الله أول محاضرة اللي مش هننطلق
+
+115
+00:08:14,940 --> 00:08:19,220
+فيها مباشرة كثير جدا هنمشي 5،6،7 شرائح هنتكلم عن
+
+116
+00:08:19,220 --> 00:08:22,980
+الـ infertility ولكن قبل ما نتكلم عن infertility و
+
+117
+00:08:22,980 --> 00:08:26,580
+infertility problem خلينا ناخد نبذة بسيطة عن الـ
+
+118
+00:08:26,580 --> 00:08:32,440
+IVF الـ IVF اختصار عبارة عن ثلاث حروف IVF كل حرف
+
+119
+00:08:32,440 --> 00:08:38,060
+عبارة عن كلمة، كل حرف عبارة عن كلمة وهي اختصار In
+
+120
+00:08:38,060 --> 00:08:45,520
+Vitro fertilization in-vitro fertilization يعني
+
+121
+00:08:45,520 --> 00:08:50,860
+التلقيح خارج الرحم أو التلقيح في الخارج أو التلقيح
+
+122
+00:08:50,860 --> 00:08:54,600
+الصناعي ولكن الأقرب هو بيسموه التلقيح الخارجي In
+
+123
+00:08:54,600 --> 00:08:58,380
+Vitro fertilization in-vitro fertilization طب ليش
+
+124
+00:08:58,380 --> 00:09:01,760
+بيسموه In-Vitro fertilization لأن عملية تلقيح
+
+125
+00:09:01,760 --> 00:09:05,640
+البويضة بِسَنجَل في الـ sperm تتم في المختبر بعيداً عن
+
+126
+00:09:05,640 --> 00:09:09,980
+السيدة وبعيداً عن رحم السيدة، طبعاً مين بالجلادة؟ أي
+
+127
+00:09:09,980 --> 00:09:12,500
+Couples ولما أقول Couples يعني مالهم في مالهم عندهم
+
+128
+00:09:12,500 --> 00:09:16,060
+مشكلة في الإنجاب أي Couples غير قادرين على الإنجاب
+
+129
+00:09:16,060 --> 00:09:18,940
+بالشكل الطبيعي بيلجؤوا إلى الـ in vitro
+
+130
+00:09:18,940 --> 00:09:21,780
+fertilization طبعاً الـ in vitro fertilization مرّ
+
+131
+00:09:21,780 --> 00:09:25,700
+بمراحل مختلفة من عملية التطور بداية من in vitro
+
+132
+00:09:25,700 --> 00:09:28,280
+fertilization وصولاً إلى الـ إكزي هو الـ
+
+133
+00:09:28,280 --> 00:09:31,810
+Intracytoplasmic sperm injection يعني أول وأبسط
+
+134
+00:09:31,810 --> 00:09:37,470
+الطرُق كانت الـ IVF و... واللي أحدث هي الـ ICSI أو 
+
+135
+00:09:37,470 --> 00:09:40,930
+الحقن المجهري بيسموه الـ ICSI والحقن المجهري طب
+
+136
+00:09:40,930 --> 00:09:44,870
+ليه سُمّي in vitro fertilization أو بالمصطلح القديم
+
+137
+00:09:44,870 --> 00:09:48,750
+كان بيسموه أطفال الأنابيب سُمّيت أطفال الأنابيب لأن
+
+138
+00:09:48,750 --> 00:09:54,490
+البويضة كانت تُلَقَّح في أنبوبة اختبار أو تُلَقَّح في
+
+139
+00:09:54,490 --> 00:09:58,890
+Petri dish أو تُلَقَّح في beaker يعني الحاوية اللي كان
+
+140
+00:09:58,890 --> 00:10:03,150
+فيها البويضة مع الـ media يا كانت Test tube يا كانت
+
+141
+00:10:03,150 --> 00:10:06,970
+بيكر يا كانت petri dish طبق عشان كده سموهم أطفال
+
+142
+00:10:06,970 --> 00:10:13,410
+الأنابيب طبعا عملية التلطيح كانت تترك للحيوانات 
+
+143
+00:10:13,410 --> 00:10:16,910
+المنوية يعني عندي بويضة بيصير إضافة عليها ال
+
+144
+00:10:16,910 --> 00:10:20,470
+seminal fluid والحيوان المنوي اللي يصل أسرع هو
+
+145
+00:10:20,470 --> 00:10:24,830
+اللي يلقح البويضة ثم بعد ذلك هذه البويضة الملقحة
+
+146
+00:10:24,830 --> 00:10:28,970
+تنقسم عدة انقسامات  للوصول إلى embryo، هذا ال embryo
+
+147
+00:10:28,970 --> 00:10:33,830
+ينقل إلى رحم السيدة لكي نحصل على عملية
+
+148
+00:10:33,830 --> 00:10:38,710
+implantation وهي انغراس في بطانة الرحم ثم نحصل على 
+
+149
+00:10:38,710 --> 00:10:42,710
+ال placenta المشيمة ثم نحصل على complete baby هذه
+
+150
+00:10:42,710 --> 00:10:48,310
+كانت فكرة ال IVF الفكرة التقليدية عشان أهم ال IVF 
+
+151
+00:10:48,310 --> 00:10:51,780
+لازم يمر بمراحل مختلفة المرحلة الأولى بسميها 
+
+152
+00:10:51,780 --> 00:10:55,060
+Ovarian Stimulation يعني أنا عندي سيدة .. السيدة
+
+153
+00:10:55,060 --> 00:10:59,320
+ده بتعطيها أدوية عشان أحفز المبيض ينتج أكبر عدد
+
+154
+00:10:59,320 --> 00:11:02,400
+من البويضات كده، ممكن تصل تلاتة؟ مال الطبيعي ..
+
+155
+00:11:02,400 --> 00:11:07,020
+السيدة ممكن تعطي تلاتة أو اتنين لأ ممكن تصل عشر أو 
+
+156
+00:11:07,020 --> 00:11:11,300
+عشرين وخمسة وعشرين بويضة وفي بعض السيدات تصل خمسة
+
+157
+00:11:11,300 --> 00:11:14,360
+وثلاثين بويضة عشان كده ال Ovarian Stimulation
+
+158
+00:11:14,360 --> 00:11:16,880
+بسميها أو بعض اللي حاببين يسموه Ovarian Hyper
+
+159
+00:11:16,880 --> 00:11:20,900
+Stimulationيعني أنا بحفز المبيض أكتر من الطبيعي
+
+160
+00:11:20,900 --> 00:11:25,700
+لينتج عدد بويضات أكتر من الطبيعي طبعا قبل ال
+
+161
+00:11:25,700 --> 00:11:27,840
+ovarian stimulation لازم يكون في عندي couple
+
+162
+00:11:27,840 --> 00:11:31,820
+examination male examination وأنا بعمله hormone
+
+163
+00:11:31,820 --> 00:11:36,080
+analysis وبعمله seminal analysis وفي عندي women
+
+164
+00:11:36,080 --> 00:11:40,940
+أو female examination من خلال ال hormone analysis
+
+165
+00:11:40,940 --> 00:11:45,440
+ومن خلال ال ultrasound إن بعمل ultrasound للسيدة 
+
+166
+00:11:45,440 --> 00:11:48,640
+عشان أشوف ال pelvic طبيعي ولا لأ ال uterus طبيعي
+
+167
+00:11:48,640 --> 00:11:51,800
+ولا لأ ال ovarian tube طبيعي ولا لأ ال ovary طبيعي
+
+168
+00:11:51,800 --> 00:11:54,620
+ولا لأ لإن ال reproductive system عند الفيميل هو
+
+169
+00:11:54,620 --> 00:11:59,440
+عبارة عن cervic رحم .. قلت رحم .. رحم و ال ovarian
+
+170
+00:11:59,440 --> 00:12:02,840
+tube مبيض ولازم كلهم يكونوا سالمين علشان تتم
+
+171
+00:12:02,840 --> 00:12:07,140
+عملية الإنجاب بشكل طبيعي ثم بعمل بعد ذلك ما يُعرف
+
+172
+00:12:07,140 --> 00:12:09,820
+باسم ال eggs .. أو عفوا ال egg and sperm
+
+173
+00:12:09,820 --> 00:12:12,980
+preparation تحضير الجاميطات الخاصة بال male و ال
+
+174
+00:12:12,980 --> 00:12:17,600
+female ثم عملية ال fertilization أو الإخصاب ثم
+
+175
+00:12:17,600 --> 00:12:21,180
+عملية ال embryoculture إن أنا البويضة المخصبة التي
+
+176
+00:12:21,180 --> 00:12:24,420
+تم تخصيبها بضعها في media ال media هذه تساعد 
+
+177
+00:12:24,420 --> 00:12:27,020
+البويضة فيها مواد غذائية تساعد البويضة على الانقسام
+
+178
+00:12:27,020 --> 00:12:32,020
+من 2 إلى 4 من 4 إلى 8 من 8 إلى 16 ومن 16 إلى 32
+
+179
+00:12:32,020 --> 00:12:35,840
+هذه عبارة عن عدد خلايا عندما تصل إلى مرحلة معينة
+
+180
+00:12:35,840 --> 00:12:39,600
+من الخلايا بعملها عملية الحاجة نسميها assist
+
+181
+00:12:39,600 --> 00:12:43,120
+hatching إن أنا بعمل تقشير للمنبرين المحيط
+
+182
+00:12:43,120 --> 00:12:46,820
+بالإمبريو عشان أسمح للإمبريو أن يخرج من المحفظة
+
+183
+00:12:46,820 --> 00:12:51,800
+الحوالين مما يؤدي إلى تسريع عملية انغرازه وانغماسه
+
+184
+00:12:51,800 --> 00:12:57,300
+في بطانة الرحم بعد معمل embryo transfer ولكن قبل 
+
+185
+00:12:57,300 --> 00:12:59,700
+معمل embryo transfer في حاجة اسمها PGD
+
+186
+00:12:59,700 --> 00:13:04,600
+Preimplantation Genetic Diagnostic إن أنا في بعض
+
+187
+00:13:04,600 --> 00:13:07,810
+ال couples بعض ال family عندهم genetic disease
+
+188
+00:13:07,810 --> 00:13:10,390
+تنتقل من generation ل generation كما أسبقنا و
+
+189
+00:13:10,390 --> 00:13:13,890
+حكينا إن أنا بدأ أعمل عملية إيقاف لهذا genetic
+
+190
+00:13:13,890 --> 00:13:19,550
+disease transfer أو transmission إن بعمل عملية
+
+191
+00:13:19,550 --> 00:13:23,210
+examination لهذه الأجنة وبرجّع الجنين الذي لا
+
+192
+00:13:23,210 --> 00:13:26,270
+يحتوي على المرض الوراثي كدا أنا بضمن إن أرجع
+
+193
+00:13:26,270 --> 00:13:31,290
+الجنين سليم وأوقف انتقال المرض الوراثي إلى ال
+
+194
+00:13:31,290 --> 00:13:34,450
+generation الجديد ثم فيما بعد بعمل embryo
+
+195
+00:13:34,450 --> 00:13:39,420
+cryopreservation بدي أجمد ال embryo كيف يتم تجميد
+
+196
+00:13:39,420 --> 00:13:45,520
+ال embryo حكينا في طريقة معينة تكنيك معين أن أنا 
+
+197
+00:13:45,520 --> 00:13:50,360
+بجمد ال embryo في درجة حرارة سالب 196 درجة مئوية
+
+198
+00:13:50,360 --> 00:13:53,960
+باستخدام ال liquid nitrogen طبعا للأسف الكل بيعتقد
+
+199
+00:13:53,960 --> 00:13:56,980
+أن أنا بضع ال embryo في ال liquid nitrogen ولكن
+
+200
+00:13:56,980 --> 00:14:01,660
+أصح ولا أدق أن أنا فقط بجمد ال embryo على بخار ال
+
+201
+00:14:01,660 --> 00:14:06,700
+liquid nitrogen طبعاً هذه الصورة توضح العملية اللي
+
+202
+00:14:06,700 --> 00:14:11,100
+اتكلمنا عليها 1. Ovarian Stimulation 2. Egg
+
+203
+00:14:11,100 --> 00:14:14,580
+Collection 3. Spare Preparation and Processing and
+
+204
+00:14:14,580 --> 00:14:18,820
+Selection 4. Fertilization تحت مسمى الـ IGZ أو IVF
+
+205
+00:14:18,820 --> 00:14:23,880
+5. Inbrot Transfer و ال Cryopreservation لعدد
+
+206
+00:14:23,880 --> 00:14:27,500
+البويضات الزائدة وفيها عدد بويضات زائدة؟ أه حكينا
+
+207
+00:14:27,500 --> 00:14:32,580
+قبل بشوية أن سيدة واحدة تعطي 13 و15 بويضة نفرض أن
+
+208
+00:14:32,580 --> 00:14:37,800
+سيدة أعطت 7 بويضات، 10 بويضات، خلينا على 10 بويضات، 
+
+209
+00:14:37,800 --> 00:14:41,180
+خلينا على 10 بويضات لقحنا الـ10 بويضات وتشاء 
+
+210
+00:14:41,180 --> 00:14:45,580
+الأقدار أن 10 بويضات تُلقح بشكل سليم 100% وتنقسم
+
+211
+00:14:45,580 --> 00:14:51,140
+وتصل إلى جنين ليس منطقيًا أو قانونيًا إعادة العشر 
+
+212
+00:14:51,140 --> 00:14:55,880
+أجنة للسيدة لأن هذا بيصير عملية منافسة ما بين 
+
+213
+00:14:55,880 --> 00:14:59,800
+الأجنة على كمية الطعام والغذاء المتوفر فبيؤدي إلى 
+
+214
+00:14:59,800 --> 00:15:04,560
+إجهاد السيدة وممكن إجهاد الأجنة فالقانون في بعض
+
+215
+00:15:04,560 --> 00:15:09,260
+الدول الأوروبية بيقول فقط جنين واحد يتم إرجاعه إلى
+
+216
+00:15:09,260 --> 00:15:14,760
+رحم السيدة جنينين على مسئولية الـcouples فبيوقعوا
+
+217
+00:15:14,760 --> 00:15:18,860
+تعهد إنه تم إرجاع جنينين على مسئوليتهم في بلادنا
+
+218
+00:15:18,860 --> 00:15:24,180
+للأسف بيرجع 1 و2 و3 و4 و5 و6 و7 و8 و10 و
+
+219
+00:15:24,180 --> 00:15:28,780
+هذا غير منطقي وغير قانوني بشكل أو بآخر طبعا تدخل 
+
+220
+00:15:28,780 --> 00:15:32,460
+فيه الأهواء الشخصية تدخل فيها العاطفة تدخل فيها
+
+221
+00:15:32,460 --> 00:15:37,440
+الأمور المادية أيضا قانونا تلاتة أكثر من تلاتة لا 
+
+222
+00:15:37,440 --> 00:15:42,380
+يجب الإرجاع لأن كل واحدة من صحة السيدة أولا و
+
+223
+00:15:42,380 --> 00:15:46,280
+ثانيا فيما بعد على الأمور المادية والنفسية للـ
+
+224
+00:15:46,280 --> 00:15:49,980
+family بعد عملية الإنشاء بعد عملية الإنشاء عشان
+
+225
+00:15:49,980 --> 00:15:55,420
+كده باقي العشرة الـ embryo سبعة أنه بأعملهم عملية
+
+226
+00:15:55,420 --> 00:15:57,920
+cryo reservation باستخدام الـ liquid nitrogen
+
+227
+00:15:57,920 --> 00:16:01,360
+باستخدام الـ liquid nitrogen هل يمكن استخدام
+
+228
+00:16:01,360 --> 00:16:06,740
+الأجنة المجمدة في المستقبل والحصول على baby طبيعي
+
+229
+00:16:06,740 --> 00:16:12,420
+صحيح ممكن استخدامهم بشكل طبيعي جدا بعد عملية
+
+230
+00:16:12,420 --> 00:16:16,840
+الإذابة أو عملية حاجة نسميها «thawing» وهي إذابة
+
+231
+00:16:16,840 --> 00:16:22,160
+يمكن وضعهم في Liquid Media علشان يرجع ينقسم ويكمل
+
+232
+00:16:22,160 --> 00:16:28,120
+عملية انقسام ثم يتم إعادتهم إلى رحم السيدة ويمكن 
+
+233
+00:16:28,120 --> 00:16:33,840
+الوصول على طفل سليم 100% عشان أحفظ الحق في عندي
+
+234
+00:16:33,840 --> 00:16:38,140
+دراسات بتقول يمكن استخدام الأجنة المجمدة والحصول
+
+235
+00:16:38,140 --> 00:16:42,000
+على طفل سليم بنسبة 100% وفي بعض الدراسات بتقول لأ
+
+236
+00:16:42,000 --> 00:16:46,100
+في بعض الدراسات بتقول الأجنة المجمدة يحدث لها 
+
+237
+00:16:46,100 --> 00:16:50,940
+عملية إتلاف بنسبة معينة 50% يعني لو أنا رجعت خمسة
+
+238
+00:16:50,940 --> 00:16:55,480
+ممكن تلاتة يتلافوا واتنين يكونوا بشكل طبيعي إذا في
+
+239
+00:16:55,480 --> 00:17:00,840
+تضارب في نتائج المقالات أو نتائج الأبحاث طبعا ما
+
+240
+00:17:00,840 --> 00:17:05,620
+بقدر أقول هذا صح وهذا صح إلا من خلال الرؤية أو من
+
+241
+00:17:05,620 --> 00:17:10,040
+خلال المشاهدة أو من خلال التجربة الشخصية من خلال
+
+242
+00:17:10,040 --> 00:17:15,080
+التجربة الشخصية إنها تنجح بنسبة 80% إعادة الأجنة
+
+243
+00:17:15,080 --> 00:17:19,460
+المجمدة تنجح بنسبة 80% بشرط إذا خُذت زينة الأجنة
+
+244
+00:17:19,460 --> 00:17:23,880
+بشكل طبيعي سليم وصار لها عملية thawing بشكل سليم
+
+245
+00:17:23,880 --> 00:17:30,190
+وصارت culturing بشكل سليم وإعادة بشكل سليم فيها
+
+246
+00:17:30,190 --> 00:17:34,770
+صورة بتبين الـXE و الـIVF Conventional IVF يعني
+
+247
+00:17:34,770 --> 00:17:41,410
+الـIVF التقليدي ببساطة فيها أنت بتضع بويضة تم 
+
+248
+00:17:41,410 --> 00:17:45,430
+إضافة الـseminal fluid عليها فبالتالي لا يوجد تدخل 
+
+249
+00:17:45,430 --> 00:17:48,790
+للإنسان في هذه العملية الحقيقية ال IVF اللي موجودة
+
+250
+00:17:48,790 --> 00:17:54,690
+على اليمين الحيوان المنوي الأكثر صحة والأكثر قدرة
+
+251
+00:17:54,690 --> 00:17:58,390
+والأسرع يصل إلى البويضة أسرع يخترق البويضة ويلقحها
+
+252
+00:17:58,750 --> 00:18:03,170
+فأنا بسميها IVF Conventional IVF ليس للإنسان أي 
+
+253
+00:18:03,170 --> 00:18:07,390
+علاقة فيها الصورة الأخرى على اليسار تحت مصطلح
+
+254
+00:18:07,390 --> 00:18:10,310
+IGESI Intracytoplasmic Sperm Injection معناها
+
+255
+00:18:10,310 --> 00:18:17,310
+إخصاب صناعي بحقن المجاري يعني أنا بأخذ بويضة بأعملها
+
+256
+00:18:17,310 --> 00:18:21,510
+fixation باستخدام ال holding pipet وبأخذ single
+
+257
+00:18:21,510 --> 00:18:24,630
+sperm باستخدام ال injection pipet وبأعمله 
+
+258
+00:18:24,630 --> 00:18:29,270
+injection داخل البويضة إذن اللي أشرف الـ Sperm من
+
+259
+00:18:29,270 --> 00:18:33,450
+أن يدخل في البويضة الإنسان الـ Embryologist عالم 
+
+260
+00:18:33,450 --> 00:18:35,870
+الأجنة أو الـ Technologist اللي بيشتغل في هذا
+
+261
+00:18:35,870 --> 00:18:43,110
+المجال كلا الطريقتين تحدث في المختبر خارج إطار
+
+262
+00:18:43,110 --> 00:18:46,790
+الرحم ولكن تحت مظلة قدرة الله يعني ممكن ينجح عملية
+
+263
+00:18:46,790 --> 00:18:50,710
+الحقن ولكن تفشل عملية الانقسام ممكن ينجح عملية
+
+264
+00:18:50,710 --> 00:18:53,870
+الحقن وتنجح عملية الانقسام وتنجح عملية الرجوع
+
+265
+00:18:53,870 --> 00:18:57,690
+ولكن تفشل عملية الـ Implantation وهي الانغراس في
+
+266
+00:18:57,690 --> 00:19:02,490
+بطانة الرحم فبالتالي هذا ما فيه تعدي على قدرة
+
+267
+00:19:02,490 --> 00:19:07,410
+الله زي ما البعض بيحاول يروّج للموضوع طب مين بيلجأ
+
+268
+00:19:07,410 --> 00:19:11,890
+للـ ICSI ومين بيلجأ للـ IVF؟ خليني أقول الـ IVF معظم 
+
+269
+00:19:11,890 --> 00:19:16,930
+اللي بيلجأوله Couples المشكلة عند الـ female لإنه
+
+270
+00:19:16,930 --> 00:19:20,690
+الـ female عنده مشاكل في عدد البويضات المنتجة بروح 
+
+271
+00:19:20,690 --> 00:19:24,670
+كطبيب بأعملها Ovarian stimulation فبأحصل على بويضات
+
+272
+00:19:24,670 --> 00:19:27,910
+الـ female طبيعي 100% بأخد ال seminal بأعمله 
+
+273
+00:19:27,910 --> 00:19:33,470
+purification وبعمل عملية pouring ل seminal على ال
+
+274
+00:19:33,470 --> 00:19:36,750
+oocyte فبيصير عملية fertilization بشكل طبيعي إذا 
+
+275
+00:19:36,750 --> 00:19:40,350
+معظم ال IVF بيكون عند ال male normal و ال female
+
+276
+00:19:40,350 --> 00:19:43,870
+abnormal أما ال ICSI ممكن يكون ال male و ال female
+
+277
+00:19:43,870 --> 00:19:46,390
+abnormal ممكن يكون ال male abnormal و ال female
+
+278
+00:19:46,390 --> 00:19:49,050
+normal ممكن تكون ال female abnormal و ال male
+
+279
+00:19:49,050 --> 00:19:53,370
+normal ولكن معظم الأسباب التي تؤدي إلى الإخصاب خُد
+
+280
+00:19:53,370 --> 00:19:55,930
+عندك فيها الأسباب الثانية في عندنا مصطلح 
+
+281
+00:19:55,930 --> 00:20:00,110
+azospermia و الـ azospermia المقصود فيها عدم وجود
+
+282
+00:20:00,110 --> 00:20:03,530
+حيوانات منوية في السائل المنوي يعني sperm
+
+283
+00:20:03,530 --> 00:20:08,550
+completely absent from the ejaculate. Oligospermia 
+
+284
+00:20:08,550 --> 00:20:12,710
+يعني وجود حيوانات منوية ولكن أقل من الوضع الطبيعي
+
+285
+00:20:12,710 --> 00:20:16,410
+يعني sperm present in low concentration. الوضع
+
+286
+00:20:16,410 --> 00:20:20,130
+الطبيعي 20 مليون هي بتكون 5 مليون، 7 مليون بسميها 
+
+287
+00:20:20,130 --> 00:20:24,850
+oligospermia. Asthenozoospermia هي عبارة عن poor
+
+288
+00:20:24,850 --> 00:20:27,370
+sperm motility. الـ sperm motility ضعيفة جدا
+
+289
+00:20:27,370 --> 00:20:31,490
+تيراتوزوسبيرميا. بعضهم بيسميه Teratozoospermia
+
+290
+00:20:31,490 --> 00:20:35,010
+بعضهم بيسميه Teratozoospermia. Teratozoospermia
+
+291
+00:20:35,010 --> 00:20:38,490
+يعني الـ poor sperm morphology. في sperm ولكن الـ
+
+292
+00:20:38,490 --> 00:20:41,290
+morphology تبعتها غير طبيعية. نسبة الـ abnormal
+
+293
+00:20:41,290 --> 00:20:44,490
+morphology عالية جدا. طبعا هذه مصطلحات قد تكون
+
+294
+00:20:44,490 --> 00:20:49,990
+جديدة على بعضكم، وقد تكون سمعت من برف أشخاص أخرى أو
+
+295
+00:20:49,990 --> 00:20:54,030
+باليبات أخرى. فبالتالي مافي عنده أي مشكلة، هنتيجي
+
+296
+00:20:54,030 --> 00:20:58,790
+معناه في مصطلحات وفي سلايدات أخرى. أسباب أخرى في 
+
+297
+00:20:58,790 --> 00:21:02,010
+عندي مشكلة في الـ sperm نفسه. الـ sperm ما بيقدر يعمل
+
+298
+00:21:02,010 --> 00:21:05,690
+sperm binding أو penetration. يعني الـ sperm okay
+
+299
+00:21:05,690 --> 00:21:09,150
+طبيعي ولكن بيجي عند الواحدة بجد مابلتسقش فيها
+
+300
+00:21:09,150 --> 00:21:12,510
+وللتسق فيها مابعملها penetration. فبالتالي مش هيحدث
+
+301
+00:21:12,510 --> 00:21:15,970
+fertilization. أو في عندي anti sperm antibody يعني 
+
+302
+00:21:15,970 --> 00:21:18,790
+أجسام مضادة ضد الـ sperm. إن موجودة الـ sperm بيعمله
+
+303
+00:21:18,790 --> 00:21:24,850
+تكسير. anti sperm antibody معناه أجسام مضادة تعمل
+
+304
+00:21:24,850 --> 00:21:27,410
+على تكسير الحيوانات المنوية. طب تكون عند الـ male
+
+305
+00:21:27,410 --> 00:21:31,390
+ممكن تكون تكون عند الـ female. ممكن تكون. طب عشان هذا
+
+306
+00:21:31,390 --> 00:21:36,330
+الحل في لحلول كثيرة هنتكلم عنها عندما نصل لعملية
+
+307
+00:21:36,330 --> 00:21:40,770
+الـ sperm processing. في عندي سبب تاني. الـ egg have
+
+308
+00:21:40,770 --> 00:21:44,210
+not fertilized by traditional IVF. يعني
+
+309
+00:21:44,210 --> 00:21:48,090
+الإمبريولوجيس عامل IVF للمرة الأولى مافي انجح. مافي
+
+310
+00:21:48,090 --> 00:21:51,630
+تلقيح. عامل IVF للمرة التانية مافي. عامل IVF للمرة
+
+311
+00:21:51,630 --> 00:21:56,870
+التالتة مافي. فمباشرة بلجأ للإجزي. سبب ما قبل الأخير
+
+312
+00:21:56,870 --> 00:22:01,830
+هو عبارة عن وجود الـ mature oocyte يعني أو وجود ان
+
+313
+00:22:01,830 --> 00:22:07,010
+mature oocyte. أصبحنا قادرين على إنتاجها وانضاجها
+
+314
+00:22:07,010 --> 00:22:11,970
+داخل المختبر. السيدة ممكن تعطيني بعد الـ ovulation
+
+315
+00:22:11,970 --> 00:22:18,190
+القبويد 13 بويضة، 10 mature و 3 immature. التلاتة
+
+316
+00:22:18,190 --> 00:22:21,410
+immature الغير ناضجات ممكن أعملهم انضاج في المختبر
+
+317
+00:22:21,410 --> 00:22:27,090
+فلازم أعملهم إجزي فيما بعد. السبب 
+
+318
+00:22:27,090 --> 00:22:31,710
+الأخير هو عبارة عن وجود بويضات مجمدة في مصبع يعني
+
+319
+00:22:31,710 --> 00:22:37,290
+السيدة عملت تلقيح صناعي، أعدد 5 بويضات، لقحت تلاتة و
+
+320
+00:22:37,290 --> 00:22:40,810
+تنتهي مجمدتهم. المرة التانية المفروض ما تخشش الـ
+
+321
+00:22:40,810 --> 00:22:44,210
+cycle من الأول خلاص. طالما في أنا عند بويضات مجمدة
+
+322
+00:22:44,210 --> 00:22:48,230
+بطلّع البويضات المجمدة بعملهم thawing و بعملهم
+
+323
+00:22:48,230 --> 00:22:52,830
+fertilization ثم بعمل عملية culturing للـ embryo ثم 
+
+324
+00:22:52,830 --> 00:22:57,310
+بعمل عملية embryo transfer. لذا هذه الأسباب المهمة
+
+325
+00:22:57,310 --> 00:23:02,550
+التي ينبغي اللجوء إلى الإجزة في حالتها. طبعا الـ IVF
+
+326
+00:23:02,550 --> 00:23:06,290
+حكينا معظم الحالات التي تؤدي إليه أن يكون الـ
+
+327
+00:23:06,290 --> 00:23:11,400
+female abnormal والـ male normal. هذه الأسباب
+
+328
+00:23:11,400 --> 00:23:16,240
+الأساسية. هنتوقف عندها تقدر من المعلومات أي طالبة
+
+329
+00:23:16,240 --> 00:23:20,920
+عندها أي سؤال مافي عنده مشكلة ممكن تسأل سواء تبعت
+
+330
+00:23:20,920 --> 00:23:24,600
+سؤالها على الـ facebook سواء تبعت سؤالها على
+
+331
+00:23:24,600 --> 00:23:28,900
+مجموعات الـ whatsapp سواء تبعت سؤالها على الـ moodle
+
+332
+00:23:28,900 --> 00:23:32,530
+بشكل طبيعي من خلال رسالة ستم الإجابة عنها إن شاء
+
+333
+00:23:32,530 --> 00:23:36,810
+الله. أرجو إنجاز مجموعة الواتس أب في أقرأ فرصة معاه
+
+334
+00:23:36,810 --> 00:23:41,810
+الممكنة لكي نتفق على ما اتبقى من الأمور. دمتم في
+
+335
+00:23:41,810 --> 00:23:45,930
+حفظ الله والسلام عليكم ورحمة الله وبركاته
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/OQJTimakS2c_raw.json b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/OQJTimakS2c_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..e6aec1a5a8ae7ee1351b6bdef6665f8621a3c2ad
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/OQJTimakS2c_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 2827, "start": 1.03, "end": 28.27, "text": "بسم الله الرحمن الرحيم والصلاة والسلام على أشرف المرسلين سيدنا محمد الصادق الأمين أما بعد بداية نرحب بكم طلبة الماجستير في قسم العلوم الطبية المخبرية كلية العلوم الصحية والمسجلين لمساق مواضيع خاصة في العلوم الطبية المخبرية سأكون معكم أنا الدكتور محمد ماروان مرقان", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 16070, 9381, 15040, 3660, 16070, 3794, 37440, 15844, 5551, 8592, 28480, 9673, 2288, 3794, 1211, 9957, 8608, 25708, 8315, 3714, 35571, 3215, 31767, 18513, 4587, 16247, 2304, 9957, 5551, 15042, 39182, 4724, 28259, 10632, 8717, 2288, 5016, 3555, 4724, 24793, 23032, 46152, 3660, 9673, 26108, 14851, 13546, 8978, 12174, 38251, 18863, 1211, 20498, 41950, 3555, 10632, 9673, 9778, 3555, 2288, 10632, 9122, 20292, 3660, 18863, 1211, 20498, 31767, 5016, 10632, 16070, 2304, 3794, 7435, 1211, 9957, 32767, 3794, 995, 4587, 3714, 2407, 46958, 40228, 16490, 33546, 3660, 8978, 18863, 1211, 20498, 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abnormal و ال male normal ولكن معظم الأسباب اللتي تؤدي إلى الإجزي خُد عندك فيها الأسباب التانية في عندنا مصطلح asospermia و ال asospermia المقصود فيها عدم وجود حيوانات منوية في السائل المنوي يعني sperm completely absent from the ejaculate oligospermia يعني وجود حيوانات منوية ولكن أقل من الوضع الطبيعي يعني sperm present in low concentration", "tokens": [2304, 43020, 6055, 30544, 2423, 6556, 32847, 4032, 2423, 7133, 2710, 35525, 19452, 20449, 19913, 2304, 16247, 35457, 16758, 13672, 31371, 6055, 33604, 16254, 30731, 33688, 7435, 11622, 1829, 16490, 10859, 3215, 43242, 4117, 8978, 11296, 16247, 35457, 16758, 16712, 7649, 10632, 8978, 43242, 8315, 3714, 9381, 9566, 1211, 5016, 382, 329, 610, 29958, 4032, 2423, 382, 329, 610, 29958, 9673, 4587, 9381, 23328, 8978, 11296, 6225, 40448, 49610, 23328, 11331, 1829, 2407, 7649, 9307, 9154, 2407, 10632, 8978, 21136, 16373, 1211, 9673, 1863, 45865, 37495, 22653, 32899, 2584, 25185, 490, 264, 10012, 326, 5256, 2545, 13348, 610, 29958, 37495, 22653, 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1206.87, "word": " ejaculate", "probability": 0.9236653645833334}, {"start": 1206.87, "end": 1208.55, "word": " oligospermia", "probability": 0.735198974609375}, {"start": 1208.55, "end": 1209.11, "word": " يعني", "probability": 0.97216796875}, {"start": 1209.11, "end": 1209.55, "word": " وجود", "probability": 0.9853515625}, {"start": 1209.55, "end": 1210.05, "word": " حيوانات", "probability": 0.9857421875}, {"start": 1210.05, "end": 1210.41, "word": " منوية", "probability": 0.9674479166666666}, {"start": 1210.41, "end": 1210.81, "word": " ولكن", "probability": 0.932373046875}, {"start": 1210.81, "end": 1211.27, "word": " أقل", "probability": 0.9656575520833334}, {"start": 1211.27, "end": 1211.57, "word": " من", "probability": 0.99267578125}, {"start": 1211.57, "end": 1212.13, "word": " الوضع", "probability": 0.985107421875}, {"start": 1212.13, "end": 1212.71, "word": " الطبيعي", "probability": 0.9754638671875}, {"start": 1212.71, "end": 1213.37, "word": " يعني", "probability": 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"word": " sperm", "probability": 0.69189453125}, {"start": 1226.11, "end": 1226.59, "word": " motility", "probability": 0.987548828125}, {"start": 1226.59, "end": 1227.09, "word": " ضعيفة", "probability": 0.98681640625}, {"start": 1227.09, "end": 1227.37, "word": " جدا", "probability": 0.984130859375}, {"start": 1227.37, "end": 1229.61, "word": " تيراتوزيوسبيرميا", "probability": 0.7958762428977273}, {"start": 1229.61, "end": 1230.51, "word": " بعضهم", "probability": 0.8235677083333334}, {"start": 1230.51, "end": 1230.81, "word": " بيسميه", "probability": 0.81923828125}, {"start": 1230.81, "end": 1231.49, "word": " تيراتوزيوسبيرميا", "probability": 0.8902254971590909}, {"start": 1231.49, "end": 1232.11, "word": " بعضهم", "probability": 0.8341471354166666}, {"start": 1232.11, "end": 1232.47, "word": " بيسميه", "probability": 0.97275390625}, {"start": 1232.47, "end": 1234.13, "word": " تيراتوزيوسبيرميا", "probability": 0.9297318892045454}, {"start": 1234.13, "end": 1235.01, "word": " تيراتوزيوسبيرميا", "probability": 0.93359375}, {"start": 1235.01, "end": 1235.65, "word": " يعني", "probability": 0.9765625}, {"start": 1235.65, "end": 1235.81, "word": " ال", "probability": 0.75537109375}, {"start": 1235.81, "end": 1236.03, "word": " poor", "probability": 0.9638671875}, {"start": 1236.03, "end": 1236.41, "word": " sperm", "probability": 0.9189453125}, {"start": 1236.41, "end": 1236.91, "word": " morphology", "probability": 0.95703125}, {"start": 1236.91, "end": 1237.07, "word": " في", "probability": 0.638671875}, {"start": 1237.07, "end": 1237.51, "word": " sperm", "probability": 0.681640625}, {"start": 1237.51, "end": 1238.39, "word": " ولكن", "probability": 0.91748046875}, {"start": 1238.39, "end": 1238.49, "word": " ال", "probability": 0.71923828125}, {"start": 1238.49, "end": 1238.85, "word": " morphology", "probability": 0.953857421875}, {"start": 1238.85, "end": 1239.27, "word": " تبعتها", "probability": 0.8353271484375}, {"start": 1239.27, "end": 1239.45, 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الأساسية هنتوقف عندها تقدر من المعلومات أي طالبة عندها أي سؤال مافي عنده مشكلة ممكن تسأل سواء تبعت سؤالها على ال facebook سواء تبعت سؤالها على مجموعات ال whatsapp سواء تبعت سؤالها على ال moodle بشكل طبيعي من خلال رسالة", "tokens": [2407, 6027, 39184, 10071, 2710, 29538, 16247, 35457, 16758, 16247, 3794, 32277, 10632, 8032, 29399, 30543, 5172, 43242, 11296, 6055, 28543, 2288, 9154, 9673, 30241, 20498, 9307, 36632, 23032, 6027, 49401, 43242, 11296, 36632, 8608, 33604, 6027, 19446, 41185, 43242, 3224, 37893, 28820, 3660, 3714, 43020, 6055, 3794, 10721, 1211, 8608, 2407, 16606, 6055, 3555, 34268, 8608, 33604, 6027, 11296, 15844, 2423, 23372, 8608, 2407, 16606, 6055, 3555, 34268, 8608, 33604, 6027, 11296, 15844, 3714, 7435, 2304, 45367, 9307, 2423, 29625, 1746, 8608, 2407, 16606, 6055, 3555, 34268, 8608, 33604, 6027, 11296, 15844, 2423, 9268, 306, 4724, 8592, 28820, 23032, 21292, 3615, 1829, 9154, 16490, 1211, 6027, 12602, 3794, 6027, 3660], "avg_logprob": -0.13406807982495852, "compression_ratio": 1.882882882882883, "no_speech_prob": 1.2934207916259766e-05, "words": [{"start": 1388.36, "end": 1388.7, "word": "والـ", "probability": 0.7555338541666666}, {"start": 1388.7, "end": 1388.96, "word": " mail", "probability": 0.41064453125}, {"start": 1388.96, "end": 1389.84, "word": " normal", "probability": 0.406982421875}, {"start": 1389.84, "end": 1391.04, "word": " هذه", "probability": 0.85498046875}, {"start": 1391.04, "end": 1391.4, "word": " الأسباب", "probability": 0.9884440104166666}, {"start": 1391.4, "end": 1391.86, "word": " الأساسية", "probability": 0.9830322265625}, {"start": 1391.86, "end": 1392.44, "word": " هنتوقف", "probability": 0.74017333984375}, {"start": 1392.44, "end": 1392.86, "word": " عندها", "probability": 0.9248046875}, {"start": 1392.86, "end": 1393.76, "word": " تقدر", "probability": 0.6753336588541666}, {"start": 1393.76, "end": 1394.08, "word": " من", "probability": 0.9296875}, {"start": 1394.08, "end": 1395.22, "word": " المعلومات", "probability": 0.9910888671875}, {"start": 1395.22, "end": 1395.78, "word": " أي", "probability": 0.497314453125}, {"start": 1395.78, "end": 1396.24, "word": " طالبة", "probability": 0.9417317708333334}, {"start": 1396.24, "end": 1396.74, "word": " عندها", "probability": 0.994140625}, {"start": 1396.74, "end": 1396.98, "word": " أي", "probability": 0.86865234375}, {"start": 1396.98, "end": 1397.44, "word": " سؤال", "probability": 0.9959309895833334}, {"start": 1397.44, "end": 1397.84, "word": " مافي", "probability": 0.854248046875}, {"start": 1397.84, "end": 1398.18, "word": " عنده", "probability": 0.65478515625}, {"start": 1398.18, "end": 1398.58, "word": " مشكلة", "probability": 0.9816080729166666}, {"start": 1398.58, "end": 1399.04, "word": " ممكن", "probability": 0.940185546875}, {"start": 1399.04, "end": 1400.04, "word": " تسأل", "probability": 0.9918212890625}, {"start": 1400.04, "end": 1400.54, "word": " سواء", "probability": 0.8333333333333334}, {"start": 1400.54, "end": 1400.92, "word": " تبعت", "probability": 0.88037109375}, {"start": 1400.92, "end": 1401.62, "word": " سؤالها", "probability": 0.994873046875}, {"start": 1401.62, "end": 1402.04, "word": " على", "probability": 0.91650390625}, {"start": 1402.04, "end": 1402.96, "word": " ال", "probability": 0.80322265625}, {"start": 1402.96, "end": 1403.36, "word": " facebook", "probability": 0.422119140625}, {"start": 1403.36, "end": 1403.8, "word": " سواء", "probability": 0.9065755208333334}, {"start": 1403.8, "end": 1404.08, "word": " تبعت", "probability": 0.9873046875}, {"start": 1404.08, "end": 1404.44, "word": " سؤالها", "probability": 0.9931640625}, {"start": 1404.44, "end": 1404.6, "word": " على", "probability": 0.9169921875}, {"start": 1404.6, "end": 1405.04, "word": " مجموعات", "probability": 0.90439453125}, {"start": 1405.04, "end": 1405.14, "word": " ال", "probability": 0.98486328125}, {"start": 1405.14, "end": 1405.52, "word": " whatsapp", "probability": 0.6527099609375}, {"start": 1405.52, "end": 1405.76, "word": " سواء", "probability": 0.93994140625}, {"start": 1405.76, "end": 1406.1, "word": " تبعت", "probability": 0.9781901041666666}, {"start": 1406.1, "end": 1407.04, "word": " سؤالها", "probability": 0.9903564453125}, {"start": 1407.04, "end": 1407.6, "word": " على", "probability": 0.93017578125}, {"start": 1407.6, "end": 1408.6, "word": " ال", "probability": 0.44140625}, {"start": 1408.6, "end": 1408.9, "word": " moodle", "probability": 0.783447265625}, {"start": 1408.9, "end": 1409.24, "word": " بشكل", "probability": 0.990234375}, {"start": 1409.24, "end": 1409.68, "word": " طبيعي", "probability": 0.9814453125}, {"start": 1409.68, "end": 1409.82, "word": " من", "probability": 0.99462890625}, {"start": 1409.82, "end": 1410.06, "word": " خلال", "probability": 0.9912109375}, {"start": 1410.06, "end": 1410.54, "word": " رسالة", "probability": 0.95068359375}], "temperature": 1.0}, {"id": 52, "seek": 142593, "start": 1410.73, "end": 1425.93, "text": "ستم الإجابة عنها إن شاء الله أرجو إنجاز مجموعة الواتس أب في أقرأ فرصة معاه الممكنة لكي نتفق على ما اتبقى من الأمور دمتم في حفظ الله والسلام عليكم ورحمة الله وبركاته", "tokens": [3794, 39237, 33688, 7435, 16758, 3660, 18871, 11296, 36145, 13412, 16606, 21984, 5551, 47341, 2407, 36145, 7435, 31377, 3714, 7435, 2304, 2407, 27884, 2423, 2407, 9307, 3794, 5551, 3555, 8978, 5551, 4587, 2288, 10721, 6156, 2288, 9381, 3660, 20449, 40294, 9673, 43020, 3660, 5296, 4117, 1829, 8717, 2655, 5172, 4587, 15844, 19446, 1975, 2655, 3555, 4587, 7578, 9154, 16247, 2304, 13063, 11778, 2304, 39237, 8978, 11331, 5172, 19913, 21984, 16070, 3794, 37440, 25894, 24793, 4032, 2288, 35571, 3660, 21984, 4032, 26890, 4117, 9307, 3224], "avg_logprob": -0.14641543486539055, "compression_ratio": 1.697142857142857, "no_speech_prob": 3.904104232788086e-05, "words": [{"start": 1410.73, "end": 1411.15, "word": "ستم", "probability": 0.69189453125}, {"start": 1411.15, "end": 1411.83, "word": " الإجابة", "probability": 0.9705810546875}, {"start": 1411.83, "end": 1412.29, "word": " عنها", "probability": 0.87060546875}, {"start": 1412.29, "end": 1412.37, "word": " إن", "probability": 0.386962890625}, {"start": 1412.37, "end": 1412.53, "word": " شاء", "probability": 0.974609375}, {"start": 1412.53, "end": 1412.75, "word": " الله", "probability": 0.95703125}, {"start": 1412.75, "end": 1413.51, "word": " أرجو", "probability": 0.7715657552083334}, {"start": 1413.51, "end": 1414.11, "word": " إنجاز", "probability": 0.8958333333333334}, {"start": 1414.11, "end": 1414.93, "word": " مجموعة", "probability": 0.9005859375}, {"start": 1414.93, "end": 1415.43, "word": " الواتس", "probability": 0.7777099609375}, {"start": 1415.43, "end": 1415.57, "word": " أب", "probability": 0.698486328125}, {"start": 1415.57, "end": 1415.69, "word": " في", "probability": 0.95849609375}, {"start": 1415.69, "end": 1416.01, "word": " أقرأ", "probability": 0.9696044921875}, {"start": 1416.01, "end": 1416.47, "word": " فرصة", "probability": 0.972900390625}, {"start": 1416.47, "end": 1416.81, "word": " معاه", "probability": 0.47314453125}, {"start": 1416.81, "end": 1417.57, "word": " الممكنة", "probability": 0.90625}, {"start": 1417.57, "end": 1417.89, "word": " لكي", "probability": 0.8927408854166666}, {"start": 1417.89, "end": 1418.33, "word": " نتفق", "probability": 0.946533203125}, {"start": 1418.33, "end": 1418.55, "word": " على", "probability": 0.88525390625}, {"start": 1418.55, "end": 1418.71, "word": " ما", "probability": 0.9208984375}, {"start": 1418.71, "end": 1419.41, "word": " اتبقى", "probability": 0.93828125}, {"start": 1419.41, "end": 1419.91, "word": " من", "probability": 0.99072265625}, {"start": 1419.91, "end": 1420.93, "word": " الأمور", "probability": 0.9762369791666666}, {"start": 1420.93, "end": 1421.57, "word": " دمتم", "probability": 0.7802734375}, {"start": 1421.57, "end": 1421.81, "word": " في", "probability": 0.93603515625}, {"start": 1421.81, "end": 1422.17, "word": " حفظ", "probability": 0.9970703125}, {"start": 1422.17, "end": 1422.49, "word": " الله", "probability": 0.9267578125}, {"start": 1422.49, "end": 1423.31, "word": " والسلام", "probability": 0.771484375}, {"start": 1423.31, "end": 1423.89, "word": " عليكم", "probability": 0.973876953125}, {"start": 1423.89, "end": 1424.83, "word": " ورحمة", "probability": 0.9757080078125}, {"start": 1424.83, "end": 1425.29, "word": " الله", "probability": 0.9560546875}, {"start": 1425.29, "end": 1425.93, "word": " وبركاته", "probability": 0.93037109375}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1450.03975, "duration_after_vad": 1404.7331249999984}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/OQJTimakS2c_raw.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/OQJTimakS2c_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..17c0824a29dc13a1c04e1f65e1ee0d08791f38ce
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/OQJTimakS2c_raw.srt
@@ -0,0 +1,1340 @@
+1
+00:00:01,030 --> 00:00:04,750
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:04,750 --> 00:00:10,130
+المرسلين سيدنا محمد الصادق الأمين أما بعد بداية
+
+3
+00:00:10,130 --> 00:00:14,070
+نرحب بكم طلبة الماجستير في قسم العلوم الطبية
+
+4
+00:00:14,070 --> 00:00:21,050
+المخبرية كلية العلوم الصحية والمسجلين لمساق مواضيع
+
+5
+00:00:21,050 --> 00:00:26,130
+خاصة في العلوم الطبية المخبرية سأكون معكم أنا
+
+6
+00:00:26,130 --> 00:00:33,250
+الدكتور محمد ماروان مرقانحصل على درجة الدكتوراه من
+
+7
+00:00:33,250 --> 00:00:37,790
+جامعة Zarland ألمانيا في تخصص molecular biology
+
+8
+00:00:37,790 --> 00:00:43,450
+and biochemistry of reproductive medicine طبعاً
+
+9
+00:00:43,450 --> 00:00:48,690
+هذا ال course هيتناول بشكل أساسي مصطلح ال IVF
+
+10
+00:00:48,690 --> 00:00:53,990
+مصطلح الإجزي وهو عبارة عن مصطلح قد يكون سمع به
+
+11
+00:00:53,990 --> 00:01:00,420
+البعض والبعض الآخر قرأ عنه في مكانهطبعاً، بدايةً،
+
+12
+00:01:00,420 --> 00:01:04,540
+مصطلح الـ XE معناه الحقن الميجاري وهو اختصار للـ
+
+13
+00:01:04,540 --> 00:01:09,060
+Intracytoplasmic injection ومصطلح الـ IDF هو مصطلح
+
+14
+00:01:09,060 --> 00:01:13,680
+In vitro fertilization أي التلقيح خارج الرحمة
+
+15
+00:01:13,680 --> 00:01:19,120
+هنتكلم عن بعض الأمور التي سنتناولها خلال هذا
+
+16
+00:01:19,120 --> 00:01:23,600
+المساق سنتكلم عن الواجبات وعن الواجبات للطالب
+
+17
+00:01:23,600 --> 00:01:29,180
+والواجبات للمدرس وننطيل في هذه المحاضرةإن شاء الله
+
+18
+00:01:29,180 --> 00:01:34,920
+أهم المواضيع التي سنتكلم عنها موضوع له علاقة مهمة
+
+19
+00:01:34,920 --> 00:01:39,600
+جداً وخاصة في وضعنا الحالي ومجتمعنا الغزاوي موضوع
+
+20
+00:01:39,600 --> 00:01:43,540
+ال infertility ما هو أو ما هي مشكلة ال infertility
+
+21
+00:01:43,540 --> 00:01:47,020
+وهل المقصود بال infertility تأخر الإنجاب، عدم
+
+22
+00:01:47,020 --> 00:01:51,080
+الإنجاب، عدم القدرة على الإنجاب أو العقوب هذي
+
+23
+00:01:51,080 --> 00:01:54,500
+المقصود أو ما هي ال infertility احنا نتكلم عنها،
+
+24
+00:01:54,500 --> 00:01:59,430
+عن مشاكلها، عن أسبابها، عن تعريفاتهاثم سوف ننتقل
+
+25
+00:01:59,430 --> 00:02:02,510
+إلى التكلم عن الـ Male and Female جميط ما هي
+
+26
+00:02:02,510 --> 00:02:06,530
+جميطات الأنثى وما هي جميطات الذكر كيف تخلق جميطات
+
+27
+00:02:06,530 --> 00:02:10,210
+الأنثى بين جثيين البوايدة وكيف تخلق جميطات الذكر
+
+28
+00:02:10,210 --> 00:02:15,390
+بين جثيين الـ sperm وكيف تنقل من مصنع التخليق إلى
+
+29
+00:02:15,390 --> 00:02:19,770
+مكان التخزين وكيف تنقل من مكان التخزين إلى مكان ال
+
+30
+00:02:19,770 --> 00:02:22,690
+fertilization ال fertilization المقصود فيها عملية
+
+31
+00:02:22,690 --> 00:02:27,460
+الإخصاب بحد ذاتهاثم سوف ننتقل إلى موضوع جديد وهو
+
+32
+00:02:27,460 --> 00:02:30,960
+الـ Stimulation Protocol at Cultural Media كيف يتم
+
+33
+00:02:30,960 --> 00:02:34,960
+تحفيز مبيض السيدة للوصول إلى عدد كبير جدا من
+
+34
+00:02:34,960 --> 00:02:38,540
+البوايضات؟ وما هي أنواع البروتوكولات التي قد
+
+35
+00:02:38,540 --> 00:02:43,040
+تستخدم؟ وما هي مدتها؟ وكيف يمكن تحديد نوع
+
+36
+00:02:43,040 --> 00:02:47,320
+البروتوكال؟ البروتوكول هل يحدد جزافا، عشوائيا،
+
+37
+00:02:47,320 --> 00:02:51,240
+بناء على الأقواء، بناء على المصالح المادية أم هناك
+
+38
+00:02:51,240 --> 00:02:56,320
+أسس معينة بناء عليها يحدد البروتوكول؟الـ culture
+
+39
+00:02:56,320 --> 00:03:00,460
+media هي عبارة عن الأوساط الزراعية التي تنمى وينمى
+
+40
+00:03:00,460 --> 00:03:04,480
+فيها الـ embryo تقريبا زي الناس اللي بتشتغل في ال
+
+41
+00:03:04,480 --> 00:03:07,940
+microbiology بتزرع بكتيريا على طبق هذا الطبق هو
+
+42
+00:03:07,940 --> 00:03:12,360
+culture media يسمح بانقسام البكتيريا وفي ال IVF أو
+
+43
+00:03:12,360 --> 00:03:18,880
+ال IGC نستخدم طبق تحتوي على media تسمح بانقسام ال
+
+44
+00:03:18,880 --> 00:03:23,610
+embryo للوصول إلى عدد معين من الخلاياسننتقل فيما
+
+45
+00:03:23,610 --> 00:03:26,250
+بعد إلى حاجة نسميها الـ sperm assessment and
+
+46
+00:03:26,250 --> 00:03:30,570
+processing selection كيف نعمل seminal analysis كيف
+
+47
+00:03:30,570 --> 00:03:33,230
+يتم عمل processing و purification للـ seminal
+
+48
+00:03:33,230 --> 00:03:36,410
+fluid كيف يتم اختيار الحيوان المنى و ال single
+
+49
+00:03:36,410 --> 00:03:41,130
+sperm من أجل عملية الحقن ثم سننتقل إلى عملية الحقن
+
+50
+00:03:41,130 --> 00:03:45,790
+بحد ذاتها وهي مصطلح XE اسمها الكمل
+
+51
+00:03:45,790 --> 00:03:50,250
+Intracytoplasmic sperm injection Intracytoplasmic
+
+52
+00:03:50,250 --> 00:03:53,170
+sperm injectionثم ننتقل إلى الـ Embryo
+
+53
+00:03:53,170 --> 00:03:56,490
+implantation and embryo biopsy كيف يتم إعادة
+
+54
+00:03:56,490 --> 00:04:01,590
+الجنين بعد عملية انقسامه في المختبر إلى رحم الأنثى
+
+55
+00:04:01,590 --> 00:04:07,010
+ورحم السيدة وكيف نحصل على جنين كامل ثم كيف يتم
+
+56
+00:04:07,010 --> 00:04:11,090
+تشخيص الجنين قبل عملية الإرجاع لأن في بعض العائلات
+
+57
+00:04:11,090 --> 00:04:15,330
+عندهم genetic disease تنتقل من generation لآخر
+
+58
+00:04:15,330 --> 00:04:19,190
+فبحاول أمنع انتقال هذا ال genetic disease من
+
+59
+00:04:19,190 --> 00:04:23,170
+الأباء إلى الأبناء من خلالفحص الجنين قبل عملية
+
+60
+00:04:23,170 --> 00:04:28,050
+إرجاعه بمصطلح embryobiopsy أو مصطلح آخر PGD
+
+61
+00:04:28,050 --> 00:04:33,130
+Preimplant Genetic Diagnostic البيوبسي هي أخذ
+
+62
+00:04:33,130 --> 00:04:37,550
+مخزعة من الجنين نفسه إذا كان الجنين 16 خلية بأخد
+
+63
+00:04:37,550 --> 00:04:41,710
+خلية مثلا ثم ننتقل إلى موضوع جديد و هو ال
+
+64
+00:04:41,710 --> 00:04:46,590
+cryopreservation كيف يتم الحفاظ على الأجنة الزائدة
+
+65
+00:04:46,590 --> 00:04:50,860
+أو البويضات الزائدةأو الحيوانات المنوية كيف يتم
+
+66
+00:04:50,860 --> 00:04:55,260
+تجميدها مصطلح معناه التجميد ويعبارة عن عملية
+
+67
+00:04:55,260 --> 00:04:59,480
+باختصار يتم فيها تخزين البويضات أو الأجنة في ال
+
+68
+00:04:59,480 --> 00:05:03,680
+liquid nitrogen الذي يصل درجة حرارته إلى minus
+
+69
+00:05:03,680 --> 00:05:09,260
+سالب 196 درجة مئوية إن كانت تبقى لدينا وقت سوف
+
+70
+00:05:09,260 --> 00:05:12,840
+نتكلم عن ال IVF equipment lab equipment ما هي
+
+71
+00:05:12,840 --> 00:05:17,160
+الأجهزة ما هي الأدوات التي يجب وينبغي أن تتواجد في
+
+72
+00:05:17,160 --> 00:05:21,600
+مختبرالبلقيح الصناعي طبعا المواضيع كتيرة مش
+
+73
+00:05:21,600 --> 00:05:25,660
+هيتناولها كلها بناء على الوقت لإن أنا بهمني ال كيف
+
+74
+00:05:25,660 --> 00:05:30,020
+ولا أهتم بالكم بهمني الطالب يطلع فاهم بكمية كبيرة
+
+75
+00:05:30,020 --> 00:05:34,140
+جدا لمعلومات المطلوبة مطلب منكوا ال powerpoint
+
+76
+00:05:34,140 --> 00:05:36,980
+lecture بشكل أساسي ال powerpoint lecture اللي
+
+77
+00:05:36,980 --> 00:05:40,420
+هتنزل على الموديل بشكل مستمر كل يوم تلاتة هي
+
+78
+00:05:40,420 --> 00:05:46,780
+المطالبين فيها فقط لا غيرالكتب المذكورة للاستذادة
+
+79
+00:05:46,780 --> 00:05:50,460
+والاستذكار مثلا في عند الـ Human Imperiology وفي
+
+80
+00:05:50,460 --> 00:05:53,520
+عند In Vitro Fertilization وهو عبارة عن أجدد كتب
+
+81
+00:05:53,520 --> 00:05:58,640
+إلى حد ما في طبع جديدة منهم في 2019 ولكن بطول
+
+82
+00:05:58,640 --> 00:06:04,280
+الكتب هو ما تم اعتماد عليهم عليهم من أجل إنتاج هذه
+
+83
+00:06:04,280 --> 00:06:10,260
+المحاضرة طبعا ال grading وال evaluation الخاصة في
+
+84
+00:06:10,260 --> 00:06:14,990
+القرن تعتمد على ثلاث مراحلالمرحلة الأولى هي ال
+
+85
+00:06:14,990 --> 00:06:17,810
+quizzes و ال humor طبعا ال attendance إن رجعنا
+
+86
+00:06:17,810 --> 00:06:22,430
+للتعليم الوجاهي ممكن يكون فيه حضور غياب و خلاله
+
+87
+00:06:22,430 --> 00:06:26,910
+ولكن حيكون فيه end quiz و humor بمعدل 30 درجة طبعا
+
+88
+00:06:26,910 --> 00:06:30,390
+ال quizzes هنحدد أوقات معينة بتوريخ معين عشان يعرف
+
+89
+00:06:30,390 --> 00:06:33,330
+الطالب إن والله في اليوم الفلاني هيكون عنده quiz
+
+90
+00:06:33,330 --> 00:06:37,990
+بالإضافة إلى ال chapter اللي المفروض يكون فيه ال
+
+91
+00:06:37,990 --> 00:06:42,430
+quiz مش هنخلف عن الموضوعثم بعد ذلك هيكون في انت
+
+92
+00:06:42,430 --> 00:06:46,770
+presentation وهي seminar بسيط كل طالبة من الطالبات
+
+93
+00:06:46,770 --> 00:06:51,130
+المسجلات في هذا المرمساق هتختار أنوان معين له
+
+94
+00:06:51,130 --> 00:06:53,510
+علاقة بال male infertility له علاقة بال female
+
+95
+00:06:53,510 --> 00:06:57,710
+infertility له علاقة بال diagnostic genetic أي شيء
+
+96
+00:06:57,710 --> 00:07:01,150
+أو أي موضوع له علاقة بال IVF أو ال XD بشكل عام
+
+97
+00:07:01,150 --> 00:07:06,930
+هتعمل عليه presentation لمدة 20 دقيقة و تسجله زي
+
+98
+00:07:06,930 --> 00:07:11,250
+ما أنا بسجل صوتمع صورة لسطح المكتب وهي بتشرح هذا
+
+99
+00:07:11,250 --> 00:07:14,950
+الموضوع و ترسله على ال model هيكون في ال model
+
+100
+00:07:14,950 --> 00:07:17,010
+ايقونة اللي هي علاقة بال seminar او ال
+
+101
+00:07:17,010 --> 00:07:21,230
+presentation وقته هنحدده هيكون وقته مفتوح هيكون
+
+102
+00:07:21,230 --> 00:07:26,950
+معاكوا شهرين تلاتة ترسله في ال seminar ثم سوف يكون
+
+103
+00:07:26,950 --> 00:07:30,130
+في النهاية ال final exam وعليه 60 درجة و هذا طبعا
+
+104
+00:07:30,130 --> 00:07:33,670
+ال quiz و ال final exam كله هيكون إلكتروني ما لم
+
+105
+00:07:33,670 --> 00:07:36,250
+يسجد أي جديد يعني ممكن في لحظة اللي عصابي أقوله
+
+106
+00:07:36,250 --> 00:07:41,650
+رجعنا للتعليم الواجهيعلى طر يكون ورقي هذا المقصود
+
+107
+00:07:41,650 --> 00:07:45,170
+في عملية ال evaluation الخاصة بالطالب وعلشان تتم
+
+108
+00:07:45,170 --> 00:07:49,590
+عملية ال evaluation و المتابعة بشكل سليم أرجو من
+
+109
+00:07:49,590 --> 00:07:54,030
+أحد الطالبات عمل مجموعة whatsapp أو مجموعة
+
+110
+00:07:54,030 --> 00:07:57,110
+facebook whatever اللي بتتلاقوه مناسب بالنسبةلكم
+
+111
+00:07:57,110 --> 00:08:02,250
+تحت عنوان ibf courses for example وإضافة للطالبات
+
+112
+00:08:02,250 --> 00:08:06,580
+زميلاتها عليه بالإضافة إلى إضافتيوإشعار إياد الأمر
+
+113
+00:08:06,580 --> 00:08:10,400
+علشان يتم متابعة بشكل مستمر وإنزال إعلانات على هذه
+
+114
+00:08:10,400 --> 00:08:14,940
+المجموعة إن شاء الله أول محاضرة اللي مش هننطلع
+
+115
+00:08:14,940 --> 00:08:19,220
+فيها شراكة كتير جدا هنمشي 5،6،7 سلايذات هنتكلم عن
+
+116
+00:08:19,220 --> 00:08:22,980
+ال infertility ولكن جابل ما نتكلم عن infertility و
+
+117
+00:08:22,980 --> 00:08:26,580
+infertility problem خلينا ناخد نوبة بسيطة عن ال
+
+118
+00:08:26,580 --> 00:08:32,440
+IVF ال IVF اختصار عبارة عن تلات حروف IVF كل حرف
+
+119
+00:08:32,440 --> 00:08:38,060
+عبارة عن كلمةكل حرف عبارة عن كلمة وهي اختصار in
+
+120
+00:08:38,060 --> 00:08:45,520
+-vitro fertilization in-vitro fertilization يعني
+
+121
+00:08:45,520 --> 00:08:50,860
+التلقيح خارج الرحم أو التلقيح في الخارج أو التلقيح
+
+122
+00:08:50,860 --> 00:08:54,600
+الصناعي ولكن الأقرب هو بيسموه التلقيح الخارجي in
+
+123
+00:08:54,600 --> 00:08:58,380
+-vitro fertilization in-vitro fertilization طب ليش
+
+124
+00:08:58,380 --> 00:09:01,760
+بيسموه in-vitro fertilization لأن عملية تلقيح
+
+125
+00:09:01,760 --> 00:09:05,640
+البويضةبسنجل في الـ sperm تتم في المختبر بعيدا عن
+
+126
+00:09:05,640 --> 00:09:09,980
+السيدة و بعيدا عن رحم السيدة طبعا مين بالجلادة؟ أي
+
+127
+00:09:09,980 --> 00:09:12,500
+كابلز و لما أقول كابلز يعني ماله في ماله عندهم
+
+128
+00:09:12,500 --> 00:09:16,060
+مشكلة في الإنجاب أي كابلز غير قادرين على الإنجاب
+
+129
+00:09:16,060 --> 00:09:18,940
+بالشكل الطبيعي بيلجأوا إلى الـ in vitro
+
+130
+00:09:18,940 --> 00:09:21,780
+fertilization طبعا ال vitro fertilization مر
+
+131
+00:09:21,780 --> 00:09:25,700
+بمراحل مختلفة من عملية التطور بداية من in vitro
+
+132
+00:09:25,700 --> 00:09:28,280
+fertilization وصولا بال إكزي هو الـ
+
+133
+00:09:28,280 --> 00:09:31,810
+Intracytoplasmic sperm injectionيعني أول و أبسط
+
+134
+00:09:31,810 --> 00:09:37,470
+الطرق كانت ال IVF و .. و اللي أحدث هي ال XE أو
+
+135
+00:09:37,470 --> 00:09:40,930
+الحقن الميجاري بيسموه ال XE و الحقن الميجاري طب
+
+136
+00:09:40,930 --> 00:09:44,870
+ليه سموه in vitro fertilization أو بالمصطلح القديم
+
+137
+00:09:44,870 --> 00:09:48,750
+كان بيسموه أطفال الأنابيب سميت أطفال الأنابيب لأن
+
+138
+00:09:48,750 --> 00:09:54,490
+البويضة كانت طلقح في انبوبة استاتيوب أو طلقح في
+
+139
+00:09:54,490 --> 00:09:58,890
+petri dish أو طلقح في beakerيعني الحاوية اللي كان
+
+140
+00:09:58,890 --> 00:10:03,150
+فيها البويضة مع ال media يا كانت test tube يا كانت
+
+141
+00:10:03,150 --> 00:10:06,970
+beaker يا كانت petri dish طبق عشان كده سموهم أطفال
+
+142
+00:10:06,970 --> 00:10:13,410
+الأنابيب طبعا عملية التلطيح كانت تترك للحيوانات
+
+143
+00:10:13,410 --> 00:10:16,910
+المنوية يعني عندي بويضة بيصير اضافت عليها ال
+
+144
+00:10:16,910 --> 00:10:20,470
+seminal fluid و الحيوان المنوي اللي يصل أسرع هو
+
+145
+00:10:20,470 --> 00:10:24,830
+اللي يلقح البويضة ثم بعد ذلك هذا البويضة الملقح
+
+146
+00:10:24,830 --> 00:10:28,970
+تنقسم عدة انقساماتلوصول إلى embryo، هذا ال embryo
+
+147
+00:10:28,970 --> 00:10:33,830
+ينقل إلى رحم السيدة لكي نحصل على عملية
+
+148
+00:10:33,830 --> 00:10:38,710
+implantation وهي انغراس في بطانة الرحم ثم نحصل على
+
+149
+00:10:38,710 --> 00:10:42,710
+ال placenta المشيمة ثم نحصل على complete baby هذه
+
+150
+00:10:42,710 --> 00:10:48,310
+كانت فكرة ال IVF الفكرة التقليدية عشان أهم ال IVF
+
+151
+00:10:48,310 --> 00:10:51,780
+لازم يمر بمراحل مختلفةالمرحلة الأولى بسميها
+
+152
+00:10:51,780 --> 00:10:55,060
+Ovarian Stimulation يعني أنا عندى سيدة .. السيدة
+
+153
+00:10:55,060 --> 00:10:59,320
+ده بتعطيها أدوية عشان أحفظ المبيع بينتاج أكبر عدد
+
+154
+00:10:59,320 --> 00:11:02,400
+من البوايدة كدهش ممكن تصل تلاتة؟ مالبقى الطبيعي ..
+
+155
+00:11:02,400 --> 00:11:07,020
+السيدة ممكن تعطي تلاتة او اتنين لأ ممكن تصل عشر او
+
+156
+00:11:07,020 --> 00:11:11,300
+عشرين وخمسة وعشرين بوايدة وفي بعض السيدات تصل خمسة
+
+157
+00:11:11,300 --> 00:11:14,360
+وتلاتين بوايدة عشان كده ال Ovarian Stimulation
+
+158
+00:11:14,360 --> 00:11:16,880
+بسميها أو بعض اللي حاببين يسموه Ovarian Hyper
+
+159
+00:11:16,880 --> 00:11:20,900
+Stimulationيعني أنا بحفظ المبيان أكتر من الطبيعي
+
+160
+00:11:20,900 --> 00:11:25,700
+لينتاج عدد بويضات أكتر من الطبيعي طبعا جابلي ال
+
+161
+00:11:25,700 --> 00:11:27,840
+ovarian stimulation لازم يكون في عندي couple
+
+162
+00:11:27,840 --> 00:11:31,820
+examination male examination و أنا بعمله hormone
+
+163
+00:11:31,820 --> 00:11:36,080
+analysis و بعمله seminal analysis و في عندي women
+
+164
+00:11:36,080 --> 00:11:40,940
+أو female examination من خلال ال hormone analysis
+
+165
+00:11:40,940 --> 00:11:45,440
+و من خلال ال ultrasoundإن بعمل ultrasound للسيدة
+
+166
+00:11:45,440 --> 00:11:48,640
+عشان أشوف ال pelvic طبيعي ولا لأ ال uterus طبيعي
+
+167
+00:11:48,640 --> 00:11:51,800
+ولا لأ ال ovarian tube طبيعي ولا لأ ال ovary طبيعي
+
+168
+00:11:51,800 --> 00:11:54,620
+ولا لأ لإن ال reproductive system عند الفيميل هو
+
+169
+00:11:54,620 --> 00:11:59,440
+عبارة عن cervic رحم .. قلت رحم .. رحم و ال ovarian
+
+170
+00:11:59,440 --> 00:12:02,840
+tube مبيع و لازم كلهم يكونوا سالمين علشان تتم
+
+171
+00:12:02,840 --> 00:12:07,140
+عملية الإنجاب بشكل طبيعي ثم بعمل بعد ذلك ما يُعرف
+
+172
+00:12:07,140 --> 00:12:09,820
+باسم ال eggs .. او عفوا ال egg and sperm
+
+173
+00:12:09,820 --> 00:12:12,980
+preparation تحضيرالجاميطات الخاصة بال male و ال
+
+174
+00:12:12,980 --> 00:12:17,600
+female ثم عملية ال fertilization أو الإجزي ثم
+
+175
+00:12:17,600 --> 00:12:21,180
+عملية ال empericulture إن أنا البويضة المخصبة التي
+
+176
+00:12:21,180 --> 00:12:24,420
+تم تخصيبها بضعها في media ال media هذه تساعد
+
+177
+00:12:24,420 --> 00:12:27,020
+البويضة فيها مواد غذائية تساعد البويضة على القسم
+
+178
+00:12:27,020 --> 00:12:32,020
+من 2 إلى 4 من 4 إلى 8 من 8 إلى 16 و من 16 إلى 32
+
+179
+00:12:32,020 --> 00:12:35,840
+هذه عبارة عن عدد خلايا عندما تصل إلى مرحلة معينة
+
+180
+00:12:35,840 --> 00:12:39,600
+من الخلايا بعملها عمليةالحاجة نسميها assist
+
+181
+00:12:39,600 --> 00:12:43,120
+hatching إن أنا بعمل تقشير للمنبرين المحيط
+
+182
+00:12:43,120 --> 00:12:46,820
+بالإمبريو عشان أسمح للإمبرو أن يخرج من المحفظة
+
+183
+00:12:46,820 --> 00:12:51,800
+الحوالين مما يؤدي إلى تسريع عملية انغرازه وانغماسه
+
+184
+00:12:51,800 --> 00:12:57,300
+في بطانة الرحم بعد معمل embryo transfer ولكن قبل
+
+185
+00:12:57,300 --> 00:12:59,700
+معمل embryo transfer في حاجة اسمها PGD
+
+186
+00:12:59,700 --> 00:13:04,600
+Preimplantation Genetic Diagnostic إن أنا في بعض
+
+187
+00:13:04,600 --> 00:13:07,810
+ال couples بعض ال familyعندهم genetic disease
+
+188
+00:13:07,810 --> 00:13:10,390
+تنتقل من generation ل generation كما أسبقنا و
+
+189
+00:13:10,390 --> 00:13:13,890
+حكينا إن أنا بدأ أعمل عملية إيقاف لهذا genetic
+
+190
+00:13:13,890 --> 00:13:19,550
+disease transfer أو transmission إن بعمل عملية
+
+191
+00:13:19,550 --> 00:13:23,210
+examination لهذه الأجنة و برجّع الجنين الذي لا
+
+192
+00:13:23,210 --> 00:13:26,270
+يحتوي على المرض الوراثي كدا أنا بضمن إن أرجع
+
+193
+00:13:26,270 --> 00:13:31,290
+الجنين سليم و أوقف انتقال المرض الوراثي إلى ال
+
+194
+00:13:31,290 --> 00:13:34,450
+generation الجديد ثم فيما بعد بعمل embryo
+
+195
+00:13:34,450 --> 00:13:39,420
+cryopreservationبدي اجمد ال embryo كيف يتم تجميد
+
+196
+00:13:39,420 --> 00:13:45,520
+ال embryo حكينا في طريقة معينة تكنيك معين ان انا
+
+197
+00:13:45,520 --> 00:13:50,360
+بجمد ال embryo في درجة حرارة سالف 196 درجة مئوية
+
+198
+00:13:50,360 --> 00:13:53,960
+استخدام ال liquid nitrogen طبعا للأسف الكل باعتقد
+
+199
+00:13:53,960 --> 00:13:56,980
+ان انا بلق ال embryo في ال liquid nitrogen ولكن
+
+200
+00:13:56,980 --> 00:14:01,660
+اصح ولا ضق ان انا فقط بجمد ال embryo على بخار ال
+
+201
+00:14:01,660 --> 00:14:06,700
+liquid nitrogenطبعاً هذه الصورة تتوضح العملية اللي
+
+202
+00:14:06,700 --> 00:14:11,100
+اتكلمنا عليها 1. Ovarian Stimulation 2. Egg
+
+203
+00:14:11,100 --> 00:14:14,580
+Collection 3. Spare Preparation and Processing and
+
+204
+00:14:14,580 --> 00:14:18,820
+Selection 4. Fertilization تحت مسمى الـ IGZ أو IVF
+
+205
+00:14:18,820 --> 00:14:23,880
+5. Inbrot Transferالـ Cryopreservation لعدد
+
+206
+00:14:23,880 --> 00:14:27,500
+البويضات الزائدة وفيها عدد بويضات زائدة؟ أه حكينا
+
+207
+00:14:27,500 --> 00:14:32,580
+قبل بشوية أن سيدة واحدة تُعطي 13 و15 بويضة نفرض أن
+
+208
+00:14:32,580 --> 00:14:37,800
+سيدة أعطت 7 بويضة، 10 بويضة، خلّينا على 10 بويضة،
+
+209
+00:14:37,800 --> 00:14:41,180
+خلّينا على 10 بويضة لقّحنا الـ10 بويضات وتشاء
+
+210
+00:14:41,180 --> 00:14:45,580
+الأقدار أن 10 بويضات تُلقّح بشكل سليم 100% وتنقسم
+
+211
+00:14:45,580 --> 00:14:51,140
+وتصل إلى جنيهليس منطقيًا أو قانونيًا إعادة العشر
+
+212
+00:14:51,140 --> 00:14:55,880
+أجنة للسيدة لأن هذا بيصير عملية منافسة ما بين
+
+213
+00:14:55,880 --> 00:14:59,800
+الأجنة على كمية الطعام والغذاء المتوفر فبيؤدي إلى
+
+214
+00:14:59,800 --> 00:15:04,560
+إجهاد السيدة وممكن إجهاد الأجنة فالقانون في بعض
+
+215
+00:15:04,560 --> 00:15:09,260
+الدول الأوروبية بتقول فقط جنين واحد يتم إرجاعه إلى
+
+216
+00:15:09,260 --> 00:15:14,760
+رحم السيدة جنينين على مسئولية الـcouples فبيواقعوا
+
+217
+00:15:14,760 --> 00:15:18,860
+تعهد إنه تم إرجاع جنينين على مسئوليتهمفي بلادنا
+
+218
+00:15:18,860 --> 00:15:24,180
+للأسف برجع 1 و 2 و 3 و 4 و 5 و 6 و 7 و 8 و 10 و
+
+219
+00:15:24,180 --> 00:15:28,780
+هذا غير منطقي و غير قانوني بشكل أو باخر طبعا تدخل
+
+220
+00:15:28,780 --> 00:15:32,460
+فيها الأهواء الشخصية تدخل فيها العاطفة تدخل فيها
+
+221
+00:15:32,460 --> 00:15:37,440
+الأمور المادية أيضا قانونا تلاتة أكثر من تلاتة لا
+
+222
+00:15:37,440 --> 00:15:42,380
+يجب الإرجاع لأن كل واحدة من صحة السيدة أولا و
+
+223
+00:15:42,380 --> 00:15:46,280
+ثانيا فيما بعدعلى الأمور المادية والنفسية للـ
+
+224
+00:15:46,280 --> 00:15:49,980
+family بعد عملية الإنشاء بعد عملية الإنشاء عشان
+
+225
+00:15:49,980 --> 00:15:55,420
+كده باقي العشرة الـ embryo سبعة أنه بأعملهم عملية
+
+226
+00:15:55,420 --> 00:15:57,920
+crib reservation باستخدام الـ liquid nitrogen
+
+227
+00:15:57,920 --> 00:16:01,360
+باستخدام الـ liquid nitrogen هل يمكن استخدام
+
+228
+00:16:01,360 --> 00:16:06,740
+الأجنة المجمدة في المستقبل و الحصول على baby طبيعي
+
+229
+00:16:06,740 --> 00:16:12,420
+صحيح ممكن استخدامهم بشكل طبيعي جدا بعد عملية
+
+230
+00:16:12,420 --> 00:16:16,840
+الإذابةأو عملية حاجة نسميها «thawing» وهي ذابة
+
+231
+00:16:16,840 --> 00:16:22,160
+يمكن وضعهم في Liquid Media علشان يرجع ينقسم ويكمل
+
+232
+00:16:22,160 --> 00:16:28,120
+عملية انقسام ثم يتم إعادتهم إلى رحم السيدة ويمكن
+
+233
+00:16:28,120 --> 00:16:33,840
+الوصول على طفل سليم 100% عشان إحفظ الحقفي عندي
+
+234
+00:16:33,840 --> 00:16:38,140
+دراسات بتقول يمكن استخدام الأجنة المجمدة والبحصول
+
+235
+00:16:38,140 --> 00:16:42,000
+على طفل سليم بنسبة 100% وفي بعض الدراسات بتقول لأ
+
+236
+00:16:42,000 --> 00:16:46,100
+في بعض الدراسات بتقول الأجنة المجمدة يحدث لها
+
+237
+00:16:46,100 --> 00:16:50,940
+عملية إتلاف بنسبة معينة 50% يعني لو أنا رجعت خمسة
+
+238
+00:16:50,940 --> 00:16:55,480
+ممكن تلاتة يتلافوا واتنين يكونوا بشكل طبيعي إذا في
+
+239
+00:16:55,480 --> 00:17:00,840
+تضارب في نتائج المقالات أو نتائج الأبحاث طبعا ما
+
+240
+00:17:00,840 --> 00:17:05,620
+بقدر أقول هذا صح وهذا صح إلامن خلال الرؤية أو من
+
+241
+00:17:05,620 --> 00:17:10,040
+خلال المشاهدة أو من خلال التجربة الشخصية من خلال
+
+242
+00:17:10,040 --> 00:17:15,080
+التجربة الشخصية إنها تنجح بنسبة 80% إعادة الأجنة
+
+243
+00:17:15,080 --> 00:17:19,460
+المجمدة تنجح بنسبة 8% بشرط إذا خُذ زينة الأجنة
+
+244
+00:17:19,460 --> 00:17:23,880
+بشكل طبيعي سليم وصار لها عملية throwing بشكل سليم
+
+245
+00:17:23,880 --> 00:17:30,190
+وصارت culturing بشكل سليم وإعادة بشكل سليمفيها
+
+246
+00:17:30,190 --> 00:17:34,770
+اندسورة بتبين الـXE والـIVF Conventional IVF يعني
+
+247
+00:17:34,770 --> 00:17:41,410
+الـIVF التقليدي ببساطة فيها انت بدردش بويضة تم
+
+248
+00:17:41,410 --> 00:17:45,430
+إضافة السمنة لفلود عليها فبالتالي لا يوجد تدخل
+
+249
+00:17:45,430 --> 00:17:48,790
+للإنسان في هذه العملية الحقيقية ال IVF اللي موجودة
+
+250
+00:17:48,790 --> 00:17:54,690
+على اليمين الحيوان المنوى الأكثر صحة والأكثر قدرة
+
+251
+00:17:54,690 --> 00:17:58,390
+والأسرع يصل إلى بويضة أسرع يخترق البويضة ويرقحها
+
+252
+00:17:58,750 --> 00:18:03,170
+فانا بسميها IVF Conventional IVF ليس للإنسان أي
+
+253
+00:18:03,170 --> 00:18:07,390
+علاقة فيها الصورة الأخرى على اليسار تحت مصطلح
+
+254
+00:18:07,390 --> 00:18:10,310
+IGESI Intracytoplasmic Sperm Injection معناها
+
+255
+00:18:10,310 --> 00:18:17,310
+ألقيح صناعة حق المجاري يعني أنا باخد بوايدة بعملها
+
+256
+00:18:17,310 --> 00:18:21,510
+fixation باستخدام ال holding pipet و باخد single
+
+257
+00:18:21,510 --> 00:18:24,630
+sperm باستخدام ال injection pipet و بعمله
+
+258
+00:18:24,630 --> 00:18:29,270
+injection داخل البوايدةإذن اللي أشبر الـ Spare من
+
+259
+00:18:29,270 --> 00:18:33,450
+أن يدخل في البوايضة الإنسان الـ Imperologist عالم
+
+260
+00:18:33,450 --> 00:18:35,870
+الأجنة أو الـ Technologist اللي بيشتغل في هذا
+
+261
+00:18:35,870 --> 00:18:43,110
+المجال كلا الطريقتين تحدث في المختبر خارج إطار
+
+262
+00:18:43,110 --> 00:18:46,790
+الرحم ولكن تحت مظل قدرته يعني ممكن ينجح عملية
+
+263
+00:18:46,790 --> 00:18:50,710
+الحقن ولكن تفشل عملية الإنقسام ممكن ينجح عملية
+
+264
+00:18:50,710 --> 00:18:53,870
+الحقن و تنجح عملية الإنقسام و تنجح عملية الرجع
+
+265
+00:18:53,870 --> 00:18:57,690
+ولكن تفشل عملية الـ Implantationوهي الإنغراس في
+
+266
+00:18:57,690 --> 00:19:02,490
+بطانة الرحل فبالتالي هذا ما فيها تعدى على قدرة
+
+267
+00:19:02,490 --> 00:19:07,410
+الله زى ما البعض بيحاول يروّج للموضوع طب مين بلجأ
+
+268
+00:19:07,410 --> 00:19:11,890
+لل إكزي ومين بلجأ لل IVF؟ خلّيني أقول ال IVF معظم
+
+269
+00:19:11,890 --> 00:19:16,930
+اللى بلجأوله Cabels المشكلة عند الفيميل لإنه
+
+270
+00:19:16,930 --> 00:19:20,690
+الفيميل عنده مشاكل في عدد البويضات المنتجة بروح
+
+271
+00:19:20,690 --> 00:19:24,670
+كطبيب بعملها ovarian stimulation فبحصل على بويضات
+
+272
+00:19:24,670 --> 00:19:27,910
+الفيميل طبيعى100% باخد ال seminal بعمله
+
+273
+00:19:27,910 --> 00:19:33,470
+purification و بعمل عملية pouring ل seminal على ال
+
+274
+00:19:33,470 --> 00:19:36,750
+oocyte فبصير عملية fertilization بشكل طبيعي إذا
+
+275
+00:19:36,750 --> 00:19:40,350
+معظم ال IVF بيكون عند ال male normal و ال female
+
+276
+00:19:40,350 --> 00:19:43,870
+abnormal أما ال XA ممكن يكون ال male و ال female
+
+277
+00:19:43,870 --> 00:19:46,390
+abnormal ممكن يكون ال male abnormal و ال female
+
+278
+00:19:46,390 --> 00:19:49,050
+normalممكن تكون ال female abnormal و ال male
+
+279
+00:19:49,050 --> 00:19:53,370
+normal ولكن معظم الأسباب اللتي تؤدي إلى الإجزي خُد
+
+280
+00:19:53,370 --> 00:19:55,930
+عندك فيها الأسباب التانية في عندنا مصطلح
+
+281
+00:19:55,930 --> 00:20:00,110
+asospermia و ال asospermia المقصود فيها عدم وجود
+
+282
+00:20:00,110 --> 00:20:03,530
+حيوانات منوية في السائل المنوي يعني sperm
+
+283
+00:20:03,530 --> 00:20:08,550
+completely absent from the ejaculate oligospermia
+
+284
+00:20:08,550 --> 00:20:12,710
+يعني وجود حيوانات منوية ولكن أقل من الوضع الطبيعي
+
+285
+00:20:12,710 --> 00:20:16,410
+يعني sperm present in low concentrationالوضع
+
+286
+00:20:16,410 --> 00:20:20,130
+الطبيعي 20 مليون هي بتكون 5 مليون، 7 مليون بسميها
+
+287
+00:20:20,130 --> 00:20:24,850
+Oregospermia أثينوسبيزيوسبيرميا هي عبارة عن poor
+
+288
+00:20:24,850 --> 00:20:27,370
+sperm motility ال sperm motility ضعيفة جدا
+
+289
+00:20:27,370 --> 00:20:31,490
+تيراتوزيوسبيرميا بعضهم بيسميه تيراتوزيوسبيرميا
+
+290
+00:20:31,490 --> 00:20:35,010
+بعضهم بيسميه تيراتوزيوسبيرميا تيراتوزيوسبيرميا
+
+291
+00:20:35,010 --> 00:20:38,490
+يعني ال poor sperm morphology في sperm ولكن ال
+
+292
+00:20:38,490 --> 00:20:41,290
+morphology تبعتها غير طبيعية نسبة ال abnormal
+
+293
+00:20:41,290 --> 00:20:44,490
+morphology عالية جدا طبعا هذه مصطلحات قد تكون
+
+294
+00:20:44,490 --> 00:20:49,990
+جديدة على بعضكموقد تكون سُمعت من برف أشخاص أخرى أو
+
+295
+00:20:49,990 --> 00:20:54,030
+باليبات أخرى فبالتالي مافي عنده أي مشكلة هنتيجي
+
+296
+00:20:54,030 --> 00:20:58,790
+معناه في مصطلحات وفي سلايدات أخرى أسباب أخرى في
+
+297
+00:20:58,790 --> 00:21:02,010
+عندي مشكلة في ال sperm نفسه ال sperm ما بيقدر يعمل
+
+298
+00:21:02,010 --> 00:21:05,690
+sperm binding أو penetration يعني ال sperm okay
+
+299
+00:21:05,690 --> 00:21:09,150
+طبيعي ولكن بيجي عند الواحدة بجد مابلتسقش فيها
+
+300
+00:21:09,150 --> 00:21:12,510
+وللتسق فيها مابعملها penetration فبالتالي مش هيحدث
+
+301
+00:21:12,510 --> 00:21:15,970
+fertilizationأو في عندي ant sperm antibody يعني
+
+302
+00:21:15,970 --> 00:21:18,790
+أجسام مضادة ضد ال sperm إن موجودة ال sperm بيعمله
+
+303
+00:21:18,790 --> 00:21:24,850
+تكسير ant sperm antibody معناه أجسام مضادة تعمل
+
+304
+00:21:24,850 --> 00:21:27,410
+على تكسير الحيوانات المنوية طب تكون عند ال male
+
+305
+00:21:27,410 --> 00:21:31,390
+ممكن تكون تكون عند ال female ممكن تكون طب عشان هذا
+
+306
+00:21:31,390 --> 00:21:36,330
+الحل في لحلول كثيرة هنتكلم عنها عندما نصل لعملية
+
+307
+00:21:36,330 --> 00:21:40,770
+ال sperm processing في عندي سبب تاني ال egg have
+
+308
+00:21:40,770 --> 00:21:44,210
+not fertilizedby traditional IVF يعني
+
+309
+00:21:44,210 --> 00:21:48,090
+الإمبريولوجيس عامل IVF للمرة الأولى مافي انجح مافي
+
+310
+00:21:48,090 --> 00:21:51,630
+تلقيح عامل IVF للمرة التانية مافي عامل IVF للمرة
+
+311
+00:21:51,630 --> 00:21:56,870
+التالتة مافي فمباشرة بلجأ للإجزي سبب ما قبل الأخير
+
+312
+00:21:56,870 --> 00:22:01,830
+هو عبارة عن وجود ال mature oocyte يعني أو وجود ان
+
+313
+00:22:01,830 --> 00:22:07,010
+mature oocyte أصبحنا قادرين على إنتاجها وانضاجها
+
+314
+00:22:07,010 --> 00:22:11,970
+داخل المختبرالسيدة ممكن تعطيني بعد ال ovulation
+
+315
+00:22:11,970 --> 00:22:18,190
+القبويد 13 بويضة، 10 mature و 3 immature التلاتة
+
+316
+00:22:18,190 --> 00:22:21,410
+immature الغير ناضجات ممكن أعملهم انضاج في المختبر
+
+317
+00:22:21,410 --> 00:22:27,090
+فلازم أعملهم إجزي فيما بعد السبب
+
+318
+00:22:27,090 --> 00:22:31,710
+الأخير هو عبارة عن وجود بويضات مجمدة في مصبع يعني
+
+319
+00:22:31,710 --> 00:22:37,290
+السيدة عملت تلقيح صناعي أعدد 5 بويضات لقحت تلاتة و
+
+320
+00:22:37,290 --> 00:22:40,810
+تنتهي مجمدتهمالمرة التانية المفروض ما تخشش ال
+
+321
+00:22:40,810 --> 00:22:44,210
+cycle من الأول خلاص طالما في أنا عند بويضات مجمدة
+
+322
+00:22:44,210 --> 00:22:48,230
+بطلّع البويضات المجمدة بعملهم thawing و بعملهم
+
+323
+00:22:48,230 --> 00:22:52,830
+fertilization ثم بعمل عملية culturing لل embryo ثم
+
+324
+00:22:52,830 --> 00:22:57,310
+بعمل عملية embryo transfer لذا هذه الأسباب المهمة
+
+325
+00:22:57,310 --> 00:23:02,550
+التي ينبغي اللجوء إلى الإجزة في حالتها طبعا ال IVF
+
+326
+00:23:02,550 --> 00:23:06,290
+حكينا معظم الحالات التي تؤدي إليه أن يكون ال
+
+327
+00:23:06,290 --> 00:23:11,400
+female abnormalوالـ mail normal هذه الأسباب
+
+328
+00:23:11,400 --> 00:23:16,240
+الأساسية هنتوقف عندها تقدر من المعلومات أي طالبة
+
+329
+00:23:16,240 --> 00:23:20,920
+عندها أي سؤال مافي عنده مشكلة ممكن تسأل سواء تبعت
+
+330
+00:23:20,920 --> 00:23:24,600
+سؤالها على ال facebook سواء تبعت سؤالها على
+
+331
+00:23:24,600 --> 00:23:28,900
+مجموعات ال whatsapp سواء تبعت سؤالها على ال moodle
+
+332
+00:23:28,900 --> 00:23:32,530
+بشكل طبيعي من خلال رسالةستم الإجابة عنها إن شاء
+
+333
+00:23:32,530 --> 00:23:36,810
+الله أرجو إنجاز مجموعة الواتس أب في أقرأ فرصة معاه
+
+334
+00:23:36,810 --> 00:23:41,810
+الممكنة لكي نتفق على ما اتبقى من الأمور دمتم في
+
+335
+00:23:41,810 --> 00:23:45,930
+حفظ الله والسلام عليكم ورحمة الله وبركاته
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/UpgBJG4XVfA.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/UpgBJG4XVfA.srt
new file mode 100644
index 0000000000000000000000000000000000000000..705570da0fb3eb6ec155eaa405b813d8ba4a5bf4
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/UpgBJG4XVfA.srt
@@ -0,0 +1,2675 @@
+1
+00:00:00,000 --> 00:00:05,240
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,240 --> 00:00:11,080
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين، طلابنا 
+
+3
+00:00:11,080 --> 00:00:15,240
+الأعزاء، نرجو من الله الكريم أن تكونوا جميعا بخير
+
+4
+00:00:15,240 --> 00:00:21,760
+وبصحة جيدة. اليوم سوف ننتقل إلى مربع جديد يعتبر جزء
+
+5
+00:00:21,760 --> 00:00:27,130
+أساسيا من عمليات الحقن المجهري، والذي سوف يتحدث عن
+
+6
+00:00:27,130 --> 00:00:31,050
+تحفيز المبيض لدى السيدات تحت مصطلح stimulation
+
+7
+00:00:31,050 --> 00:00:35,490
+protocol. ثم ننتقل إلى أنواع الـ media التي تستخدم
+
+8
+00:00:35,490 --> 00:00:40,030
+من أجل نضج البويضة إذا كانت البويضة غير ناضجة
+
+9
+00:00:40,030 --> 00:00:45,590
+لحظة السحب أو وضع البويضة المخصبة في الـ media معينة
+
+10
+00:00:45,590 --> 00:00:51,710
+بناء على أيام انقسامها. عملية stimulation protocol
+
+11
+00:00:51,710 --> 00:00:57,310
+مهمة جدا في عمليات الحقن المجهري، ومن خلال عملية
+
+12
+00:00:57,310 --> 00:01:02,830
+تحفيز المبيض، نصل إلى عدد معين من البويضات التي
+
+13
+00:01:02,830 --> 00:01:07,870
+ينبغي أن تكون ناضجة وينبغي أن تكون صالحة للإخصاب
+
+14
+00:01:07,870 --> 00:01:12,890
+بأن تكون تحتوي على first polar body. اليوم سوف
+
+15
+00:01:12,890 --> 00:01:18,010
+نتحدث عن هذه البروتوكولات المختلفة، وكيف، وما هي، وما
+
+16
+00:01:18,010 --> 00:01:23,490
+الاختلاف ما بين هذه البروتوكولات. في البداية، في بدايات
+
+17
+00:01:23,490 --> 00:01:27,730
+عملية التلقيح الصناعي أو عملية الإخصاب الصناعي 
+
+18
+00:01:27,730 --> 00:01:32,770
+المعترف بها، اسمها In vitro fertilization، يعني أطفال
+
+19
+00:01:32,770 --> 00:01:38,530
+الأنابيب. كان هناك حالات يحدث فيها حمل، ولكن من أجل
+
+20
+00:01:38,530 --> 00:01:44,390
+زيادة فرصة نجاح عملية التلقيح الصناعي، وزيادة فرصة
+
+21
+00:01:44,390 --> 00:01:49,370
+وجود حمل ونجاح عملية التلقيح، يجب علينا أن نصل إلى
+
+22
+00:01:49,370 --> 00:01:53,790
+مرحلة، وهي مرحلة الحصول على أكبر عدد من البويضات
+
+23
+00:01:53,790 --> 00:02:00,090
+الناضجة من أجل ضمان إلى حد ما نجاح عملية الحقن أو 
+
+24
+00:02:00,090 --> 00:02:07,130
+الـ تلقيح الصناعي. فبالتالي من أجل تحسين عملية الحقن
+
+25
+00:02:07,130 --> 00:02:13,090
+ومن أجل تحسين معدل الحقن، ومن أجل تحسين معدل حدوث
+
+26
+00:02:13,090 --> 00:02:18,810
+عملية الحمل pregnancy rate، يجب علينا أن نسحب ونجمع
+
+27
+00:02:18,810 --> 00:02:23,490
+أكبر عدد من البويضات الناضجة التي تكون صالحة
+
+28
+00:02:23,490 --> 00:02:27,250
+لعملية الإخصاب. فالبويضة الناضجة تكون صالحة لعملية
+
+29
+00:02:27,250 --> 00:02:31,790
+الإخصاب إذا كانت على شكل بويضة تحتوي على first
+
+30
+00:02:31,790 --> 00:02:36,510
+polar body. فهذه العملية التي يتم من خلال تحسين
+
+31
+00:02:36,510 --> 00:02:42,160
+وزيادة عدد البويضات المخصبة، يتم من خلال حث المبيض
+
+32
+00:02:42,160 --> 00:02:47,740
+على إنتاج أكبر عدد من خلال تحفيزه بهرمونات خارجية
+
+33
+00:02:47,740 --> 00:02:52,560
+أو داخلية، تشبه الهرمونات التي تعمل على المبيض من 
+
+34
+00:02:52,560 --> 00:02:55,520
+أشهر الهرمونات التي تعمل على المبيض، بناء على ما
+
+35
+00:02:55,520 --> 00:03:01,580
+درسنا، الـ FSH والـ LH. فبالتالي أنا كإنسان بشتغل في
+
+36
+00:03:01,580 --> 00:03:05,840
+الـ embryologist، بدي أعمل تحفيز للمبيض، وغادر طبعا 
+
+37
+00:03:05,840 --> 00:03:08,400
+الطبيب هو اللي بيحدد الـ dose، بناء على الـ history
+
+38
+00:03:08,400 --> 00:03:13,330
+باستخدام Exogenous أو Endogenous هرمون، في الغالب 
+
+39
+00:03:13,330 --> 00:03:17,770
+بيكون FSH، في الغالب بيكون FSH أو ما يُعرف باسم
+
+40
+00:03:17,770 --> 00:03:22,550
+Gonadotropin، والـ Gonadotropin هما نوعين FSH و LH.
+
+41
+00:03:22,550 --> 00:03:27,790
+خلال السنوات المتعاقبة التي تتعلق بعمليات الحقن 
+
+42
+00:03:27,790 --> 00:03:31,670
+المجهري والتلقيح الصناعي، يوجد هناك العديد من الـ
+
+43
+00:03:31,670 --> 00:03:35,670
+protocols التي يمكن استخدامها، وكل الـ protocol له
+
+44
+00:03:35,670 --> 00:03:39,270
+advantage وله disadvantage. فلا يمكن استخدام
+
+45
+00:03:39,270 --> 00:03:43,290
+protocol واحد لجميع السيدات. فبالتالي كل حالة
+
+46
+00:03:43,290 --> 00:03:48,070
+مستقلة عن الأخرى، ولها protocol خاص فيها. أول من
+
+47
+00:03:48,070 --> 00:03:52,590
+استخدم عملية الـ protocols وعملية تحفيز المبيض كان
+
+48
+00:03:52,590 --> 00:03:58,190
+Porter وزملاؤه. هما استخدموا ما يسمى الـ Gonadotropin
+
+49
+00:03:58,190 --> 00:04:02,650
+Releasing Hormone Agonist في عملية الـ IVF treatment.
+
+50
+00:04:02,650 --> 00:04:07,350
+فهو أول من استخدم عملية حقن السيدات
+
+51
+00:04:07,350 --> 00:04:13,130
+بهرمونات خارجية من أجل تحفيز المبيض تحت مصطلح GnRH Agonist.
+
+52
+00:04:13,130 --> 00:04:17,790
+أي Gonadotropin Releasing Hormone Agonist.
+
+53
+00:04:17,790 --> 00:04:22,730
+هذا كان أول واحد. فيما يلي تتابع الأحداث وتتاليتها
+
+54
+00:04:23,160 --> 00:04:27,520
+وتم تطوير قاعدة البروتوكولات تقليديًا. تطوير عدد
+
+55
+00:04:27,520 --> 00:04:32,420
+مرتبط oocytes كان ممكنًا فقط بعد تطوير التحكم 
+
+56
+00:04:32,420 --> 00:04:37,900
+التسلسلي ovarian. بمعنى آخر، يمكن للسيدة أن تعطي
+
+57
+00:04:37,900 --> 00:04:41,700
+عدد كبير جدًا من البويضات، أكبر من الوضع الطبيعي.
+
+58
+00:04:41,700 --> 00:04:45,480
+جعلنا في الوضع الطبيعي واحدة، اثنتين، ثلاث بويضات.
+
+59
+00:04:45,480 --> 00:04:50,580
+بينما إذا خضعت لمصطلح يسمى COS وهو عبارة عن 
+
+60
+00:04:50,580 --> 00:04:54,740
+Controlled Ovarian Stimulation، تحصل على عدد كبير من
+
+61
+00:04:54,740 --> 00:05:00,000
+البويضات، قد يصل إلى 25 بويضة، وبعض الحالات تصل
+
+62
+00:05:00,000 --> 00:05:05,100
+إلى 35 بويضة. طبعا للأسف كلهم مش ناضجين، ولكن أقل شيء
+
+63
+00:05:05,100 --> 00:05:09,460
+ثلاث إلى أربعة بيكونوا ناضجين. شو يعني Controlled Ovarian
+
+64
+00:05:09,460 --> 00:05:12,680
+Hyperstimulation Protocol؟ هو عبارة عن نظام
+
+65
+00:05:12,680 --> 00:05:17,540
+وبروتوكول يستخدم فيه هرمونات تعمل على تحفيز المبيض
+
+66
+00:05:17,810 --> 00:05:22,350
+ولكن تحت عملية السيطرة. ما بيغرد المبيض .. المبيض
+
+67
+00:05:22,350 --> 00:05:26,450
+ما بيخرج سرب، وبيصير يشتغل من تلقاء نفسه، ما بيصير
+
+68
+00:05:26,450 --> 00:05:32,670
+عندي hyper response، لا الـ response بيكون محكم ..
+
+69
+00:05:32,670 --> 00:05:37,970
+أنا كـ technologist أو كـ embryologist متحكم فيه بناء
+
+70
+00:05:37,970 --> 00:05:41,870
+على الـ dose اللي بعطيها للسيدة. طبعا في الوضع 
+
+71
+00:05:41,870 --> 00:05:46,460
+الطبيعي، وفي الدورة الشهرية الطبيعية، تنمو عدة من 
+
+72
+00:05:46,460 --> 00:05:51,280
+الـ Anterior Follicle الموجودة في المبيض، ولكن ما 
+
+73
+00:05:51,280 --> 00:05:55,540
+بيصل إلى الـ Grafian Follicle وهي لحظة الـ ovulation
+
+74
+00:05:55,540 --> 00:05:59,460
+واحدة، اثنتين، ثلاث، ماكسيموم. الـ interaction between
+
+75
+00:05:59,460 --> 00:06:03,040
+growing follicle and pituitary gland and
+
+76
+00:06:03,040 --> 00:06:06,620
+hypothalamus prevented multifollicle growth and
+
+77
+00:06:06,620 --> 00:06:10,140
+allowed only one follicle complete maturation and
+
+78
+00:06:10,140 --> 00:06:13,400
+arrive to the stage of ovulation. إيش اللي بيخلي
+
+79
+00:06:13,630 --> 00:06:16,790
+المبيض في الوضع الطبيعي ما بيطلع أكتر من ثلاث 
+
+80
+00:06:16,790 --> 00:06:20,350
+بويضات أو بويضتين كحد أقصى؟ إنه في عندي نوع من 
+
+81
+00:06:20,350 --> 00:06:23,370
+أنواع الـ correlation، نوع من أنواع الـ interaction
+
+82
+00:06:23,370 --> 00:06:27,850
+نوع من أنواع الـ connection ما بين الـ hypothalamus
+
+83
+00:06:27,850 --> 00:06:32,230
+كـ master والـ pituitary gland التي تفرز الهرمونات
+
+84
+00:06:32,230 --> 00:06:36,590
+وال FSH وال LH، والـ growing follicle. فهذه الهرمونات اللي
+
+85
+00:06:36,590 --> 00:06:40,140
+بتكون رايحة جاية بين التلت مناطق، هذه هي اللي بتتحكم
+
+86
+00:06:40,140 --> 00:06:43,340
+في عمل المبيض، وبتقول للمبيض يكفي إنتاج بويضتين
+
+87
+00:06:43,340 --> 00:06:47,960
+أو ثلاثة كحد أقصى في الوضع الطبيعي، لأن هذا
+
+88
+00:06:47,960 --> 00:06:52,020
+شغل هرمونات. كل ما زاد هرمون الـ FSH، كل ما زاد معدل
+
+89
+00:06:52,020 --> 00:06:57,840
+نضج البويضات وهكذا. فبالتالي controlled ovarian
+
+90
+00:06:57,840 --> 00:07:02,100
+stimulation required multiply daily injection and
+
+91
+00:07:02,100 --> 00:07:05,620
+frequently monitoring scanning that creating
+
+92
+00:07:05,620 --> 00:07:08,580
+directly and indirectly caused loss of working
+
+93
+00:07:08,580 --> 00:07:14,280
+time. للأسف وجدوا أن عملية تحفيز المبيض المتحكم به
+
+94
+00:07:14,280 --> 00:07:18,460
+المسمى Controlled Ovarian Hyper Stimulation، يتم من خلال
+
+95
+00:07:18,460 --> 00:07:23,400
+إعطاء الزوجة أو إعطاء السيدة جرعات متتالية ويومية 
+
+96
+00:07:23,400 --> 00:07:28,460
+من الهرمونات بشكل متتالي، تكون هذه الجرعات تحت
+
+97
+00:07:28,460 --> 00:07:32,720
+السيطرة وتحت المراقبة، بالإضافة إلى مراقبة وقياس 
+
+98
+00:07:32,720 --> 00:07:37,320
+المبيض والـ Diameter الخاصة بالفوليكول. ولكن للأسف
+
+99
+00:07:37,320 --> 00:07:40,860
+وجدوا أن هذه العملية، عملية بشكل عام متعبة 
+
+100
+00:07:40,860 --> 00:07:47,880
+مرهقة، مكلفة، إضافة إلى أنها مضيعة للوقت. في النظام 
+
+101
+00:07:47,880 --> 00:07:52,240
+العالمي اللي يعتمد على أن الشخص يشتغل 8 ساعات 
+
+102
+00:07:52,240 --> 00:07:56,120
+يوميا أو 9 ساعات يوميا. فإذا هذه السيدة كانت عاملة
+
+103
+00:07:56,120 --> 00:08:00,280
+تشتغل في وظيفة معينة، فبدأت تخضع للـ control of
+
+104
+00:08:00,280 --> 00:08:04,910
+ovarian stimulation، من الراحة إلى حد ما، وعدم الإجهاد.
+
+105
+00:08:04,910 --> 00:08:08,350
+فبالتالي هتخسر من ساعات أو هتقلل من ساعات دوامها.
+
+106
+00:08:08,350 --> 00:08:12,190
+فبالتالي الإنتاج بتأثر. عشان كده قالوا إنه يؤثر على
+
+107
+00:08:12,190 --> 00:08:18,430
+عدد ساعات العمل بشكل مباشر أو غير مباشر. ولكن 
+
+108
+00:08:18,430 --> 00:08:22,970
+المشكلة الأساسية هي مشكلة مادية. فوجدوا إن الناس 
+
+109
+00:08:22,970 --> 00:08:26,510
+والسيدات اللي بتخضع لدى الـ protocol، بدفع كميات
+
+110
+00:08:26,510 --> 00:08:30,960
+مهولة من الأموال. فبالتالي بتكون عندي عبء مالي على 
+
+111
+00:08:30,960 --> 00:08:35,560
+هذه العائلة. The most important medical problem
+
+112
+00:08:35,560 --> 00:08:39,480
+associated with controlled ovarian stimulation is the
+
+113
+00:08:39,480 --> 00:08:43,940
+risk for ovarian hyperstimulation syndrome. risk
+
+114
+00:08:43,940 --> 00:08:48,760
+الخطير أو خليني أقول إن المعضلة الخطيرة اللي ممكن
+
+115
+00:08:48,760 --> 00:08:54,180
+تظهر عند هؤلاء السيدات اللواتي يخضعن إلى الـ 
+
+116
+00:08:54,180 --> 00:08:59,400
+Controlled Ovarian Stimulation. عفوا، ممكن يصير عندهم
+
+117
+00:08:59,400 --> 00:09:03,940
+حالة سميتها قبل شوية Hyper Stimulation. ولكن إن ظهر
+
+118
+00:09:03,940 --> 00:09:08,140
+عليهم symptoms، بسميها في هذه الحالة Ovarian Hyper
+
+119
+00:09:08,140 --> 00:09:12,640
+Stimulation Syndrome. وحنتكلم عنها باستفاضة في الشق
+
+120
+00:09:12,640 --> 00:09:15,480
+الثاني من المحاضرة. الـ Ovarian Hyper Stimulation
+
+121
+00:09:15,480 --> 00:09:18,460
+Syndrome تتميز إن في عندي enlargement في الـ Ovary.
+
+122
+00:09:18,460 --> 00:09:24,380
+زيادة في blood capillary permeability، بالإضافة إلى
+
+123
+00:09:24,380 --> 00:09:29,100
+shifting للـ fluid داخل الـ space المحيط بالـ
+
+124
+00:09:29,100 --> 00:09:33,920
+abdominal المحيط بالـ ovary. طبعًا، this result
+
+125
+00:09:33,920 --> 00:09:37,980
+يؤدي إلى تكوين ما يُعرف باسم hypovolemia. بيؤدي إلى
+
+126
+00:09:37,980 --> 00:09:40,980
+تكوين hemoconcentration. بيؤدي إلى تكوين
+
+127
+00:09:40,980 --> 00:09:43,480
+hypercoagulopathy.
+
+128
+00:09:45,660 --> 00:09:49,940
+high blood coagulability. هنتكلم عنها باستفاضة، كيف 
+
+129
+00:09:49,940 --> 00:09:55,280
+ممكن يصير عندك high blood في الـ coagulation. الـ OHSS 
+
+130
+00:09:55,280 --> 00:10:01,260
+maybe have some complicated like acute renal 
+
+131
+00:10:01,260 --> 00:10:09,380
+failure, hypovolemic shock, thrombosis.
+
+132
+00:10:13,940 --> 00:10:19,840
+في عندي مشاكل في الجهاز التنفسي، بالإضافة إلى أنه
+
+133
+00:10:19,840 --> 00:10:24,780
+قد يكون قاتل. شو يعني قد يكون قاتل؟ اه، قد يكون قاتل.
+
+134
+00:10:24,780 --> 00:10:31,620
+الـ OHSS اللي لم يعالج هيكون يؤدي بالوفاة للسيدات
+
+135
+00:10:31,620 --> 00:10:35,260
+المصابات فيه. طبعا أنا مش هستفاض في هذا الموضوع، ولكن 
+
+136
+00:10:35,260 --> 00:10:39,780
+كانت علاج بسيط. هنعرف كيف بيكون قاتل بناء على الـ
+
+137
+00:10:39,780 --> 00:10:44,560
+severity الخاصة فيه. الـ risk for OHSS can be high
+
+138
+00:10:44,560 --> 00:10:49,180
+as 6% in young women with the polycystic ovarian
+
+139
+00:10:49,180 --> 00:10:52,600
+syndrome. طبعا الـ polycystic ovarian syndrome حالة
+
+140
+00:10:52,600 --> 00:10:58,420
+مرضية تختلف عن الـ OHSS. الـ polycystic ovarian
+
+141
+00:10:58,420 --> 00:11:03,100
+syndrome قد تؤدي إلى إعاقة الحمل بسبب وجود تكيسات
+
+142
+00:11:03,100 --> 00:11:08,310
+حول المبيض أو تكيسات في المبايض هذا مرض يختلف عن
+
+143
+00:11:08,310 --> 00:11:12,390
+المرض الآخر اسمه ovarian hyperstimulation syndrome
+
+144
+00:11:12,390 --> 00:11:15,830
+PCOS
+
+145
+00:11:15,830 --> 00:11:20,270
+ممكن يحدث بشكل طبيعي هذا يحدث بفعل effect أو 
+
+146
+00:11:20,270 --> 00:11:26,470
+influence factor زي ال exogenous hormone طيب كيف
+
+147
+00:11:26,470 --> 00:11:30,970
+يمكن تحضير المبيض وإعطائها بعض الأنواع من
+
+148
+00:11:30,970 --> 00:11:34,150
+الأدوية التي يمكن أن تستخدم في تحفيز المبايض؟
+
+149
+00:11:35,730 --> 00:11:40,570
+Controlled Ovarian Hyperstimulation كان فيما سبق
+
+150
+00:11:40,570 --> 00:11:48,190
+يتم فيه استخدام نوع معين من الدواء يسمى Colombirin
+
+151
+00:11:48,190 --> 00:11:53,250
+Citrate هذا النوع من أنواع الأدوية فيما بعد تم 
+
+152
+00:11:53,250 --> 00:11:58,710
+استبداله بـHuman Menopausal Gonadotropin وخدوا
+
+153
+00:11:58,710 --> 00:12:04,250
+بالكم من كلمة monopiosal و human يعني بشري وله
+
+154
+00:12:04,250 --> 00:12:08,750
+علاقة بسن اليأس عند السيدات ثم تم استبداله بالـ
+
+155
+00:12:08,750 --> 00:12:12,810
+Urinary FSH Preparation ثم تم استبداله بالـ
+
+156
+00:12:12,810 --> 00:12:17,130
+Recombinant FSH يعني لو أنا عرفت التدريج تبعه،
+
+157
+00:12:17,130 --> 00:12:21,330
+هيكون في البداية عندي من الأسفل إلى الأعلى بناء
+
+158
+00:12:21,330 --> 00:12:25,590
+على التقدم هيكون فيه Human Menopausal Gonadotropin
+
+159
+00:12:25,590 --> 00:12:29,600
+Urinary FSH Preparation والـ
+
+160
+00:12:29,600 --> 00:12:33,700
+Recombinant FSH Preparation إذا ما هي
+
+161
+00:12:33,700 --> 00:12:37,420
+ال gonadotropins؟ ال gonadotropins هي الهرمونات المهمة
+
+162
+00:12:37,420 --> 00:12:41,340
+التي تفرز من ال anterior pituitary gland وتأثير
+
+163
+00:12:41,340 --> 00:12:46,300
+على ال specific cell in the ovary هذه الهرمونات
+
+164
+00:12:46,300 --> 00:12:51,300
+أفضل مثال عليها الـ FSH أو هي عبارة عن الـ FSH و
+
+165
+00:12:51,300 --> 00:12:56,950
+LH ال human menopausal gonadotropin تم استخدامه
+
+166
+00:12:56,950 --> 00:13:04,630
+في البداية عام 1960 وهو عبارة عن drug يستخدم من
+
+167
+00:13:04,630 --> 00:13:09,590
+أجل تحفيز المبيض The initial preparations were
+
+168
+00:13:09,590 --> 00:13:15,530
+very impure with mainly contaminated protein with
+
+169
+00:13:15,530 --> 00:13:22,030
+less than 5% of protein being bioactive بمعنى آخر
+
+170
+00:13:22,030 --> 00:13:26,460
+أن هذا الدواء اللي سميته human menopausal
+
+171
+00:13:26,460 --> 00:13:31,100
+gonadotropin والذي استخدم في بدايات 1960 من أجل
+
+172
+00:13:31,100 --> 00:13:37,900
+تحفيز المبايض أول ما تم إنشائه كان باحتواء على
+
+173
+00:13:37,900 --> 00:13:42,060
+كمية كبيرة جدا من الشوائب فهو not a pure drug
+
+174
+00:13:42,060 --> 00:13:45,740
+بالإضافة إلى أنه في بعض ال contaminants البروتين
+
+175
+00:13:45,740 --> 00:13:49,280
+اللي مفروض ما تكون موجودة فالمفروض لمن بدأ يعمل
+
+176
+00:13:49,280 --> 00:13:53,800
+stimulation للسيدة لل ovary خاص بسيدة معينة لازم
+
+177
+00:13:53,800 --> 00:13:58,820
+أعطيها pure drug يعني pure هرمون ما في other
+
+178
+00:13:58,820 --> 00:14:03,280
+compound ممكن تأثر سلبًا على هذا ال structure
+
+179
+00:14:03,280 --> 00:14:12,000
+الموجود في جسد السيدة مع ذلك وبتتالي الاختبارات
+
+180
+00:14:12,000 --> 00:14:16,120
+على الهرمونات المستخلصة والمستخدمة والمصنعة في عام
+
+181
+00:14:16,120 --> 00:14:23,060
+1980 تم تحسين وتطوير نوع من أنواع ال drug عمل نوع
+
+182
+00:14:23,060 --> 00:14:26,060
+من أنواع الـ Improvement للـ Action والـ
+
+183
+00:14:26,060 --> 00:14:29,720
+Structure والـ Composition الخاصة بالـ
+
+184
+00:14:29,720 --> 00:14:35,820
+Gonadotropin تحت مصطلح مهم جدا هو الـ Urinary FSH
+
+185
+00:14:35,820 --> 00:14:40,560
+وفكرته ببساطة أن في عند السيدات اللي بتصل لمرحلة
+
+186
+00:14:40,560 --> 00:14:47,120
+ال Menopause هيصير كمية releasing للـ FSH و LH في
+
+187
+00:14:47,120 --> 00:14:50,190
+الـ urine بكمية كبيرة جدافكانوا ياخدوا هذا ال
+
+188
+00:14:50,190 --> 00:14:54,330
+urine ويعملوله عملية extraction أو عملية خلينا
+
+189
+00:14:54,330 --> 00:14:58,850
+نقول extraction لل FSH و extraction لل LH الموجودة
+
+190
+00:14:58,850 --> 00:15:01,830
+في كميات المهولة من ال urine الخاص بالسيدات اللي
+
+191
+00:15:01,830 --> 00:15:06,270
+وصلوا لـ Menopause وبيعملوا بعد كده عملية تنقية إذا
+
+192
+00:15:06,270 --> 00:15:11,310
+سيدات بيجمعوا منهم ال urine بس سيدة وصلت إلى سن
+
+193
+00:15:11,310 --> 00:15:15,970
+ال Menopause جمعوا ال urine حلجوا كمية كبيرة جدا من
+
+194
+00:15:15,970 --> 00:15:20,410
+ال FSH و LH يفرص في عينة ال urineعملوا extraction
+
+195
+00:15:20,410 --> 00:15:23,610
+للـ FSH والـ LH بعدين عملوا عملية ال purification
+
+196
+00:15:23,610 --> 00:15:28,030
+باستخدام ال monoclonal antibody أو ما يُعرف باسم
+
+197
+00:15:28,030 --> 00:15:32,810
+ال affinity chromatography ثم تطور هذا الأمر فأصبح
+
+198
+00:15:32,810 --> 00:15:37,230
+لدينا قدرة على استخدام ال DNA technology أو
+
+199
+00:15:37,230 --> 00:15:40,930
+biotechnology تحت مصطلح recombinant DNA وأكيد
+
+200
+00:15:40,930 --> 00:15:44,330
+عارفين إيش عن ال recombinant DNA ببساطة جدا ال
+
+201
+00:15:44,330 --> 00:15:48,650
+recombinant DNA هو أنا بجيب fragment من الـ DNA للـ
+
+202
+00:15:48,650 --> 00:15:53,010
+target protein أو target هرمون وبعملها عملية
+
+203
+00:15:53,010 --> 00:15:56,470
+ligation مع vector like plasmid و plasmid هذا
+
+204
+00:15:56,470 --> 00:15:59,450
+بعملها insertion داخل الـ E.coli for example و
+
+205
+00:15:59,450 --> 00:16:02,790
+بدفع ال E.coli إنها تتطور وتنمو وتتضاعف بكميات
+
+206
+00:16:02,790 --> 00:16:06,590
+كبيرة جدا مما يسمح لها بعمل replication و
+
+207
+00:16:06,590 --> 00:16:09,630
+transcription و translation للمادة اللي ورا فيها
+
+208
+00:16:09,630 --> 00:16:14,610
+plus ال inserted DNA فبالتالي ال protein هينتج
+
+209
+00:16:14,610 --> 00:16:19,160
+هعمله عملية collection extraction purification
+
+210
+00:16:19,160 --> 00:16:26,360
+سميته Recombinant FSH وأول ما تم استخدام نوع معين
+
+211
+00:16:26,360 --> 00:16:31,540
+من أنواع ال Ovary سموها Chinese Hamster Ovary
+
+212
+00:16:31,540 --> 00:16:37,860
+Cell Line CHO Chinese Hamster Ovary Cell Line
+
+213
+00:16:37,860 --> 00:16:43,300
+وذلك لأنها تنتج كمية كبيرة جدا من البروتين البروتين
+
+214
+00:16:43,300 --> 00:16:47,540
+الموجود في جسم الإنسان post modification حتى بعد
+
+215
+00:16:47,540 --> 00:16:50,920
+ال post modification لأن احنا عارفين إن معظم
+
+216
+00:16:50,920 --> 00:16:54,420
+الهرمونات Alpha subunit و Beta subunit ال Alpha
+
+217
+00:16:54,420 --> 00:16:58,220
+subunit متشابهة في الجميع لل Beta subunit مختلفة
+
+218
+00:16:58,220 --> 00:17:03,020
+فوجدوا ان ال chinese hamster ovarian cell line
+
+219
+00:17:03,020 --> 00:17:06,680
+تستطيع ان تنتج Beta subunit من ال gonadotropin
+
+220
+00:17:06,680 --> 00:17:11,260
+هرمون يشبه بشكل كبير جدا جدا جدا ل human
+
+221
+00:17:11,260 --> 00:17:16,480
+gonadotropin فبالتالي أستطيع أن أجبرها وأسخرها لكي
+
+222
+00:17:16,480 --> 00:17:21,660
+تنتج هذا الهرمون المطلوب control أو مايعرف اسم ال
+
+223
+00:17:21,660 --> 00:17:25,640
+hamster أو ال chinese hamster cell line were
+
+224
+00:17:25,640 --> 00:17:29,860
+selected as recipient cell since they were easily
+
+225
+00:17:29,860 --> 00:17:33,420
+transferred with a foreign DNA and are capable to
+
+226
+00:17:33,420 --> 00:17:36,500
+synthesize a very large amount of complex
+
+227
+00:17:36,500 --> 00:17:40,840
+glycoprotein هي في عندي كمان صفتين جديدتين رغم
+
+228
+00:17:40,840 --> 00:17:44,590
+أنها بتفرز ما يشبهما يوجد في جسم الإنسان they
+
+229
+00:17:44,590 --> 00:17:47,250
+could be grown in the cell culture on a large
+
+230
+00:17:47,250 --> 00:17:50,790
+scale ممكن أنميها بكميات كبيرة جدا وكميات مهولة
+
+231
+00:17:50,790 --> 00:17:56,070
+اللي تخدمني على الصعيد ال industrial لو أنا فرجت
+
+232
+00:17:56,070 --> 00:18:01,210
+فرقت ببساطة جدا ما بين ال urinary FSH و ال human
+
+233
+00:18:01,210 --> 00:18:06,190
+menopausal gonadotropin ال human menopausal
+
+234
+00:18:06,190 --> 00:18:11,350
+gonadotropin يُرمز له HMG human menopausal G
+
+235
+00:18:11,350 --> 00:18:15,950
+-gonadotropin بيقول ببساطة إن نسبة ال FSH إلى ال
+
+236
+00:18:15,950 --> 00:18:21,410
+LH في ال HMG 1 إلى 1 بينما في ال urinary FSH
+
+237
+00:18:21,410 --> 00:18:26,190
+preparation كمية contained a small amount of LH
+
+238
+00:18:26,190 --> 00:18:30,910
+يعني كمية ال LH إلى كمية ال FSH متساوية في ال
+
+239
+00:18:30,910 --> 00:18:34,610
+human menopausal gonadotropin ولكن كمية ال LH
+
+240
+00:18:34,610 --> 00:18:39,300
+قليلة في ال urinary FSH من اسمه Urinary FSH يعني
+
+241
+00:18:39,300 --> 00:18:44,820
+كمية الـ FSH عارية جدا طبعا الـ Follicles may be
+
+242
+00:18:44,820 --> 00:18:49,140
+exposed to the high level of LH وجدوا أن تعرض الـ
+
+243
+00:18:49,140 --> 00:18:53,180
+Ovary لكميات كبيرة جدا من الـ LH خلال عملية ال
+
+244
+00:18:53,180 --> 00:18:57,640
+development وقبل عملية ال ovulation يلعب دورة
+
+245
+00:18:57,640 --> 00:19:02,080
+سلبية على عملية ال ovulation بشكلها الأساسي مش
+
+246
+00:19:02,080 --> 00:19:07,550
+منطقي أعرض ال Ovary و ال Follicle لدوز عالي من
+
+247
+00:19:07,550 --> 00:19:13,010
+ال LH في اليوم 13 و14 لأن إذا بتذكروا حكينا إن
+
+248
+00:19:13,010 --> 00:19:16,790
+ال LH بيلعب دور مهم جدا في ال ovulation فالمفروض
+
+249
+00:19:16,790 --> 00:19:20,610
+بناء على ال chart ما يظهر إلا على هيئة sharp في
+
+250
+00:19:20,610 --> 00:19:26,150
+اليوم 13 و14 ظهوره قبل هذه الأيام يعني في أيام ال
+
+251
+00:19:26,150 --> 00:19:31,320
+development له تأثير سلبي فبالتالي المفروض ما يكون
+
+252
+00:19:31,320 --> 00:19:36,040
+موجود فمنطقيا ان تأثير ال human menopausal
+
+253
+00:19:36,040 --> 00:19:40,260
+gonadotropin إذا قرنته بال urinary FSH preparation
+
+254
+00:19:40,260 --> 00:19:45,500
+على ال development هيكون سيء إلى حد ما سيء إلى حد
+
+255
+00:19:45,500 --> 00:19:50,000
+ما فبالتالي high level of LH during their early
+
+256
+00:19:50,000 --> 00:19:52,520
+stage of development when stimulated with human
+
+257
+00:19:52,520 --> 00:19:55,920
+menopausal gonadotropin to compare to the urinary
+
+258
+00:19:55,920 --> 00:20:00,880
+FSH هذا بيعمل عملية failure للـ follicle maturation
+
+259
+00:20:00,880 --> 00:20:05,160
+إلى حد ما من ال study have demonstrated that too
+
+260
+00:20:05,160 --> 00:20:08,420
+much LH during this time هي follicular
+
+261
+00:20:08,420 --> 00:20:15,160
+development before ovulation day هيلعب دورة سلبية
+
+262
+00:20:15,160 --> 00:20:19,540
+ودورة سلبية في عملية ال maturation ولاجوا انه
+
+263
+00:20:19,540 --> 00:20:25,680
+associated with more than one rule او more than one point
+
+264
+00:20:25,680 --> 00:20:28,910
+for example the first one بيعمل reduction في ال rate
+
+265
+00:20:28,910 --> 00:20:31,730
+of fertilization بيعمل reduction في ال pregnancy
+
+266
+00:20:31,730 --> 00:20:35,210
+rate وبيعمل increase في ال spontaneous abortion
+
+267
+00:20:35,210 --> 00:20:39,050
+يعني السيدة إذا اتعرضت لل human
+
+268
+00:20:39,050 --> 00:20:43,570
+menopausal gonadotropin يعني ال ovary اتعرضت لدوز
+
+269
+00:20:43,570 --> 00:20:47,970
+عالي جدا من ال LH قبل أيام التطوير في الأشهر أيام
+
+270
+00:20:47,970 --> 00:20:52,410
+الأولى هذا وجدوا أنه بلعب دور سلبي و بأثر بشكل
+
+271
+00:20:52,410 --> 00:20:56,240
+سلبي على عملية ال oocyte maturation والـ Follicular
+
+272
+00:20:56,240 --> 00:20:59,660
+Maturation أو Development هذه نقطة وجدوا إنه
+
+273
+00:20:59,660 --> 00:21:02,820
+بيأثر سلبًا على ال rate of fertilization و rate of
+
+274
+00:21:02,820 --> 00:21:06,100
+pregnancy زيادة ال LH في هذه المرحلة بيعمل
+
+275
+00:21:06,100 --> 00:21:10,920
+reduction فالعلاقة علاقة عكسية أيضًا وجدوا إنه
+
+276
+00:21:10,920 --> 00:21:15,680
+بيعمل زيادة في احتمالية حدوث ال abortion بسبب أو
+
+277
+00:21:15,680 --> 00:21:20,220
+من نوع spontaneous abortion هذا قران اتبان لل
+
+278
+00:21:20,220 --> 00:21:25,310
+human menopausal gonadotropin والـ Urinary FSH طب لو
+
+279
+00:21:25,310 --> 00:21:28,390
+أنا قرنت بين الـ Recombinant FSH و الـ Human
+
+280
+00:21:28,390 --> 00:21:32,510
+Menopausal Gonadotropin The main source of Human 
+
+281
+00:21:32,510 --> 00:21:36,810
+Human Menopausal Gonadotropin and FSH preparation هي الـ
+
+282
+00:21:36,810 --> 00:21:40,870
+urine زي ما حكينا بشكل أساسي أن المصدر الأساسي للـ
+
+283
+00:21:40,870 --> 00:21:44,530
+FSH في الـ Human Menopausal Gonadotropin هو عبارة 
+
+284
+00:21:44,530 --> 00:21:47,890
+عن الـ FSH مستخلص من الـ urine sample الخاص
+
+285
+00:21:47,890 --> 00:21:52,500
+بالسيدات التي وصلت إلى أو اللواتي وصلنا إلى الـ
+
+286
+00:21:52,500 --> 00:21:55,780
+menopause الـ development الجديدة أو التكنيك
+
+287
+00:21:55,780 --> 00:21:58,280
+الجديد أو التكنولوجيا الجديدة اللي سميناها
+
+288
+00:21:58,280 --> 00:22:02,820
+recombinant يعني إيه؟ لأ ما إلها علاقة ما إلها
+
+289
+00:22:02,820 --> 00:22:06,880
+علاقة بال in vitro .. in vivo لأ أنا بصنع ال FSH
+
+290
+00:22:06,880 --> 00:22:13,020
+in vitro يشبه بشكل كبير قد تصل ل 99% و بعض الأحيان
+
+291
+00:22:13,020 --> 00:22:17,880
+إلى 100% إلى ال human FSH this preparation have an
+
+292
+00:22:17,880 --> 00:22:22,260
+extremely high purity which makes them attractive as
+
+293
+00:22:22,260 --> 00:22:27,480
+an alternative to human menopausal gonadotropin and
+
+294
+00:22:27,480 --> 00:22:33,060
+urinary FSH وذلك لأن سلبياته و ال complications
+
+295
+00:22:33,060 --> 00:22:37,960
+خاصة فيه تعتبر قليلة جدا مقارنة بال complications
+
+296
+00:22:37,960 --> 00:22:42,600
+التي تنتج عن ال human menopausal gonadotropin or
+
+297
+00:22:42,600 --> 00:22:50,320
+urinary FSH دراسات جريت في عام 2003 وجدت أنه مافي
+
+298
+00:22:50,320 --> 00:22:52,900
+significant مافي difference significant ما بين
+
+299
+00:22:52,900 --> 00:22:58,520
+استخدام ال HMG واستخدام ال recombinant FSH من حيث
+
+300
+00:22:58,520 --> 00:23:03,980
+نمو وفطور ال void من حيث معدل الحمل ومن حيث ال
+
+301
+00:23:03,980 --> 00:23:09,740
+live births كلام يحترم هذا في 2003 طب لو اتقدم الزمن
+
+302
+00:23:09,740 --> 00:23:18,800
+وجدوا في 2008 فيه دراسات وجدت انه في اختلاف في
+
+303
+00:23:18,800 --> 00:23:24,660
+ال live birth rate ما بين استخدام ال HMG و ال
+
+304
+00:23:24,660 --> 00:23:29,440
+recombinant FSH فوجدوا ان السيدات او الحالات اللي
+
+305
+00:23:29,440 --> 00:23:33,920
+أخذت recombinant FSH معدل الحمل عندهم أعلى من
+
+306
+00:23:33,920 --> 00:23:37,180
+السيدات اللي أخذوا human menopausal gonadotropin
+
+307
+00:23:37,180 --> 00:23:41,660
+و هذا المنطق جدا بسبب الأسباب اللي ذكرناها في مصدر
+
+308
+00:23:41,660 --> 00:23:48,300
+في أول شغلة مصطلح سموه جنادو تروبيين releasing
+
+309
+00:23:48,300 --> 00:23:53,340
+hormone agonist GnRHa
+
+310
+00:23:53,340 --> 00:23:58,100
+جنادو تروبيين releasing hormone agonist وهو عبارة
+
+311
+00:23:58,100 --> 00:24:02,260
+عن نوع من أنواع ال protocols التي تستخدم من أجل عمل
+
+312
+00:24:02,260 --> 00:24:05,540
+down regulation for pituitary gland شو يعني down
+
+313
+00:24:05,540 --> 00:24:08,700
+regulation أنه بتقول للـ pituitary gland بيكفيكي
+
+314
+00:24:08,700 --> 00:24:14,780
+إفراز FSH و LH أنا هقوم بالوظيفة من حيث إعطاء
+
+315
+00:24:14,780 --> 00:24:19,780
+هرمونات خارجية وبالتالي أوقف إفراز الهرمونات
+
+316
+00:24:19,780 --> 00:24:25,180
+الطبيعية وأعطي هرمونات مصنعة من الخارج أتحكم في
+
+317
+00:24:25,180 --> 00:24:26,620
+كميتها كطبيب 
+
+318
+00:24:30,380 --> 00:24:33,720
+طيب بالنسبة للـ gonadotropin releasing hormone
+
+319
+00:24:33,720 --> 00:24:37,980
+agonist قسموها إلى عدة أقسام بناء على ال duration
+
+320
+00:24:37,980 --> 00:24:42,380
+قسموها إلى long protocol يعني بتاخد عدد أيام أكثر
+
+321
+00:24:42,380 --> 00:24:47,000
+short protocol و ultra short protocol يعني في عندي
+
+322
+00:24:47,000 --> 00:24:50,480
+ultra short protocol و في عندي short protocol و في
+
+323
+00:24:50,480 --> 00:24:53,440
+عندي longer protocol احنا عارفين قد ايش عدد أيام كل
+
+324
+00:24:53,440 --> 00:24:57,260
+protocol The stimulation may be initiated in the
+
+325
+00:24:57,260 --> 00:25:00,520
+first day of that cycle إذا والله أنا بدأت ال
+
+326
+00:25:00,520 --> 00:25:03,060
+stimulation من أول يوم في الدورة من أول يوم
+
+327
+00:25:03,060 --> 00:25:07,120
+bleeding بسمي هذا ال protocol short protocol the
+
+328
+00:25:07,120 --> 00:25:12,920
+cycle preceding the stimulation cycle is long
+
+329
+00:25:12,920 --> 00:25:17,520
+protocol بمعنى آخر بمعنى آخر أنه أنا عملت
+
+330
+00:25:17,520 --> 00:25:21,320
+stimulation في ال cycle السابقة هذا ال cycle
+
+331
+00:25:21,320 --> 00:25:25,070
+السابق يعني أنا أخذت ثلاث أربع خمس أيام من أيام
+
+332
+00:25:25,070 --> 00:25:28,970
+الدورة السابقة فمعناه هاخد سبع أيام من الدورة
+
+333
+00:25:28,970 --> 00:25:31,970
+السابقة و سبع أيام من الدورة الجديدة حتى أصل إلى
+
+334
+00:25:31,970 --> 00:25:34,830
+يوم الطبويد يعني أخذت أربعة عشر أيام بسميه long
+
+335
+00:25:34,830 --> 00:25:38,790
+protocol هاي الفرق بين ال long و ال short ال short
+
+336
+00:25:38,790 --> 00:25:42,950
+protocol بدأت من أول يوم الدورة عمل stimulation ال
+
+337
+00:25:42,950 --> 00:25:46,170
+long protocol بدأت من الأيام السابقة أخذت أيام
+
+338
+00:25:46,170 --> 00:25:49,830
+سابقة من الدورة السابقة أو أيام إضافية من الدورة
+
+339
+00:25:49,830 --> 00:25:55,540
+السابقة يعني كإني بدأت مثلاً مثلاً في اليوم رقم 20 من
+
+340
+00:25:55,540 --> 00:26:01,020
+الدورة السابقة و أخذت آخر 8 أيام و أخذت كمان 10
+
+341
+00:26:01,020 --> 00:26:03,720
+أيام من الدورة الجديدة و أخذت كإني ما أخذت 18 يوم
+
+342
+00:26:03,720 --> 00:26:06,980
+و بيساعدها طبعاً هذه الأيام ال duration تعتمد على
+
+343
+00:26:06,980 --> 00:26:12,180
+عمر السيدة طبيعة المبيض مستوى هرموني القامع ش
+
+344
+00:26:12,180 --> 00:26:17,720
+سنتحدث عن هذا مستقبلاً إن شاء الله several years
+
+345
+00:26:17,720 --> 00:26:23,200
+later following a several studies have been shown
+
+346
+00:26:23,200 --> 00:26:27,660
+that the long protocol gave the best result in the
+
+347
+00:26:27,660 --> 00:26:30,540
+term of pregnancy rate يعني بناء على الدراسات
+
+348
+00:26:30,540 --> 00:26:34,720
+الجديدة التي يتم استحداثها مقارنة ما بين ال
+
+349
+00:26:34,720 --> 00:26:38,820
+different protocol وجدوا أن معدل ال pregnancy rate
+
+350
+00:26:38,820 --> 00:26:43,600
+بيكون أفضل إذا استخدمنا ال long protocol بمنطق جيد
+
+351
+00:26:44,030 --> 00:26:46,770
+في الـ long protocol أنا ما بخضع و ما بجبر
+
+352
+00:26:46,770 --> 00:26:50,990
+البويضات أن تتطور بسرعة و ما بعطيها دوز عالي لأ
+
+353
+00:26:50,990 --> 00:26:54,810
+أنا بعطي دوز معقول خلال فترة زمنية طويلة يعني كإني
+
+354
+00:26:54,810 --> 00:26:58,790
+بخل المبيض يشتغل بوضعه الطبيعي ولكن تحت تأثير
+
+355
+00:26:58,790 --> 00:27:02,030
+الهرمونات اللي أنا بعطيها مش الهرمونات الطبيعية
+
+356
+00:27:02,030 --> 00:27:06,290
+عشان كده ممكن يكون عندي ال pregnancy rate أفضل عند
+
+357
+00:27:06,290 --> 00:27:12,090
+استخدام ال long protocol في مادة بيسموها 
+
+358
+00:27:12,090 --> 00:27:16,170
+gonadotropin-releasing hormone analogues شو يعني
+
+359
+00:27:16,170 --> 00:27:20,210
+analogues؟ ال analogues ببساطة هي عبارة عن نوع من
+
+360
+00:27:20,210 --> 00:27:24,890
+أنواع المواد المصنعة مشبه مادة طبيعية أصلية موجودة
+
+361
+00:27:24,890 --> 00:27:28,670
+في جسم الإنسان فسموها gonadotropin-releasing
+
+362
+00:27:28,670 --> 00:27:32,190
+hormone analogues هي عبارة عن short peptide من
+
+363
+00:27:32,190 --> 00:27:35,750
+gonadotropin-releasing hormone يعني هي عبارة عن
+
+364
+00:27:35,750 --> 00:27:39,290
+هرمون اسمه gonadotropin-releasing hormone ولكن
+
+365
+00:27:39,290 --> 00:27:44,860
+short peptide that causes profound inhibition of
+
+366
+00:27:44,860 --> 00:27:48,400
+estrogen and androgen synthesis وجدوا أن
+
+367
+00:27:48,400 --> 00:27:52,360
+الـ Analogues هذه، اللي هي عبارة عن short peptide
+
+368
+00:27:52,360 --> 00:27:55,600
+من الـ Gonadotropin releasing hormone تلعب دور
+
+369
+00:27:55,600 --> 00:28:00,340
+مهمة جدا في تثبيط الاستروجين وتثبيط الاندروجين
+
+370
+00:28:01,980 --> 00:28:05,220
+Gonadotropin-releasing hormone analogues were
+
+371
+00:28:05,220 --> 00:28:09,280
+created by a series of modifications in
+
+372
+00:28:09,280 --> 00:28:12,260
+Gonadotropin-releasing hormone molecule that led
+
+373
+00:28:12,260 --> 00:28:16,960
+to the development of a new agonist or antagonist يعني
+
+374
+00:28:16,960 --> 00:28:19,740
+أنا جبت الـ Gonadotropin-releasing hormone عملت
+
+375
+00:28:19,740 --> 00:28:23,220
+عليه modifications، حصلت على مادة جديدة اسمها
+
+376
+00:28:23,220 --> 00:28:26,660
+Gonadotropin-releasing hormone analogues وجود هذه
+
+377
+00:28:26,660 --> 00:28:30,400
+المادة الجديدة أدت إلى وجود two protocols عظيmain
+
+378
+00:28:30,620 --> 00:28:33,440
+البروتوكول الأول اسمه agonist البروتوكول الثاني
+
+379
+00:28:33,440 --> 00:28:41,240
+اسمه antagonist agonist يعني محفز مناهض يعني
+
+380
+00:28:41,240 --> 00:28:47,280
+بيعمل ضد بمعنى آخر ال agonist بيعمل ببساطة جدا
+
+381
+00:28:47,280 --> 00:28:52,600
+enhancing for gonadotropin production كأنه بيجبر
+
+382
+00:28:52,600 --> 00:28:56,650
+ال anterior lobe أو بطيوتة رجلان على إنتاج كمية
+
+383
+00:28:56,650 --> 00:29:01,390
+كبيرة جدا من الـ gonadotropin بين جثين FSH وLH ما
+
+384
+00:29:01,390 --> 00:29:08,370
+يستمر إعطاء هذا الهرمون الخارجي كدا الخلية أو
+
+385
+00:29:08,370 --> 00:29:11,790
+الغدة بتقول و الله طالما فيه هرمون يأتي من الخارج
+
+386
+00:29:11,790 --> 00:29:17,150
+أنا مافي داعي أفرز فتتوقف الغدة عن الإفراز فيبقى
+
+387
+00:29:17,150 --> 00:29:21,170
+الجسم فقط يستجيب إلى كمية الـ gonadotropin التي
+
+388
+00:29:21,170 --> 00:29:25,770
+تأتي من الخارج والتي تتمثل في الـ LH والـ FSH يعني
+
+389
+00:29:25,770 --> 00:29:28,970
+فكرته أنه في البداية بيحفز الـ Anterior Lobe
+
+390
+00:29:28,970 --> 00:29:32,590
+و Pituitary Gland لإفراز الـ Gonadotropin بعد فترة مع
+
+391
+00:29:32,590 --> 00:29:35,350
+استمرار ال injection هتيجي في الـ Anterior Lobe
+
+392
+00:29:35,350 --> 00:29:38,290
+و Pituitary Gland ليش تجيد نفسها طالما فيه هرمون
+
+393
+00:29:38,290 --> 00:29:42,410
+جايس بييجي بيصير reduction في ال level of FSH LH
+
+394
+00:29:42,410 --> 00:29:46,210
+المفروض من الـ Anterior Lobe و Pituitary Gland ويتم
+
+395
+00:29:46,210 --> 00:29:50,590
+استعادة استعادة عنهم من الـ Gonadotropin releasing
+
+396
+00:29:50,590 --> 00:29:55,920
+hormone الذي يأتي من الخارج اولا وهذا المصطلح اللي
+
+397
+00:29:55,920 --> 00:30:02,160
+سموه Gonadotropin agonist agonist يعني يحفز ثم
+
+398
+00:30:02,160 --> 00:30:06,720
+يثبط وهي اللي شفناها حفظ الانتريو اللوب و بطيوت 
+
+399
+00:30:06,720 --> 00:30:11,740
+رجلها وبعدين ثبتها traditionally a tutoring down
+
+400
+00:30:11,740 --> 00:30:15,060
+regulation has been the most common protocol
+
+401
+00:30:15,060 --> 00:30:19,560
+utilized in IUI or IVF يعني كل ال protocolات اللي
+
+402
+00:30:19,560 --> 00:30:23,180
+لها علاقة بال stimulation وظيفتها الأساسية أنها
+
+403
+00:30:23,180 --> 00:30:28,170
+تقوم بإيقاف الـ anterior loop و Pituitary Gland من
+
+404
+00:30:28,170 --> 00:30:31,750
+إفراز الـ FSH والـ LH يعني كذا بتعمل ال blocking خد
+
+405
+00:30:31,750 --> 00:30:38,270
+بالك و ال blocking مؤقت طبعا من خلال إعطاء هرمون
+
+406
+00:30:38,270 --> 00:30:41,910
+مصنع في الخارج نعطيه subcutaneous ال
+
+407
+00:30:41,910 --> 00:30:44,650
+administration of gonadotropin releasing hormone
+
+408
+00:30:44,650 --> 00:30:48,010
+agonist will be initiated the cause of releasing
+
+409
+00:30:48,010 --> 00:30:51,430
+FSH وLH from the anterior loop هذا الكلام حكيناه
+
+410
+00:30:51,430 --> 00:30:57,060
+في ال slide الفقرة الأخيرة بعد أكثر من يوم بعد
+
+411
+00:30:57,060 --> 00:31:01,200
+several days الإعطاء المستمر بيعمل inhibition و
+
+412
+00:31:01,200 --> 00:31:04,060
+dropping في مستوى الافاسش والقلاتش المفروض من
+
+413
+00:31:04,060 --> 00:31:06,780
+هذه ال loop أو من هذه ال gland دي اسمها anterior
+
+414
+00:31:06,780 --> 00:31:10,460
+pituitary gland نسبة إلى وجود كمية كبيرة جدا
+
+415
+00:31:10,460 --> 00:31:14,240
+في الدم فمفيش داعي تفرز طالما في كمية كافية في
+
+416
+00:31:14,240 --> 00:31:18,520
+الدم عالية في الدم أنا ك loop اسمي anterior loop و
+
+417
+00:31:18,520 --> 00:31:22,730
+pituitary gland ما بفرز ال hormone طالما موجودة So
+
+418
+00:31:22,730 --> 00:31:26,890
+dropping in the circulating concentration of FSH
+
+419
+00:31:26,890 --> 00:31:33,010
+and LH and to prevent LH wave or surge من خلال
+
+420
+00:31:33,010 --> 00:31:37,770
+مصطلح بيسمي desensitization أي receptor 
+
+421
+00:31:37,770 --> 00:31:41,960
+desensitization يعني الفكرة ببساطة أنه أنا كطبيب
+
+422
+00:31:41,960 --> 00:31:45,340
+بأعطي الـ gonadotropin-releasing hormone agonist 
+
+423
+00:31:45,340 --> 00:31:51,480
+عدة أيام بحفظ الخلية أو الغدة التي تُسمى anterior
+
+424
+00:31:51,480 --> 00:31:55,540
+lobe وبتوتر الغدة لإفراز الـ FSH والـ LH باستمرار
+
+425
+00:31:55,540 --> 00:32:00,120
+عند الـ injection الغدة تقول المستوى عالي أنا ما بدي 
+
+426
+00:32:00,120 --> 00:32:04,120
+أفرز فتتوقف عن إفراز الـ normal FSH والـ LH 
+
+427
+00:32:04,120 --> 00:32:08,870
+الـ human الـ indigenous مع استمرار الإعطاء
+
+428
+00:32:08,870 --> 00:32:11,350
+بيصير الـ dropping في الـ level للـ FSH والـ LH
+
+429
+00:32:11,350 --> 00:32:14,770
+الـ dropping في الـ level للـ FSH والـ LH يؤدي
+
+430
+00:32:14,770 --> 00:32:20,290
+إلى منع تكوين الـ LH search or قلقش with تحت مصطلح
+
+431
+00:32:20,290 --> 00:32:25,510
+بنسميها desensitization أو receptor desensitization
+
+432
+00:32:25,510 --> 00:32:29,110
+so what's the meaning of desensitization what's
+
+433
+00:32:29,110 --> 00:32:31,170
+the meaning of receptor desensitization
+
+434
+00:32:31,810 --> 00:32:35,450
+desensitization of this phenomenon occurs when
+
+435
+00:32:35,450 --> 00:32:39,450
+receptor decreases its response to agonist at high
+
+436
+00:32:39,450 --> 00:32:44,190
+concentration يعني أنا كـ response موجود على سطح الـ
+
+437
+00:32:44,190 --> 00:32:48,070
+ovary أو خلايا معينة في الـ ovary باستقبل الـ FSH
+
+438
+00:32:48,070 --> 00:32:53,750
+هيصير استقبالي للـ FSH ورضي على الـ FSH من خلال الـ
+
+439
+00:32:53,750 --> 00:33:00,030
+response قليل جداً هذه بنسميها desensitization it's
+
+440
+00:33:00,030 --> 00:33:06,250
+a process through which وهذا يحدث من خلال إعطاء جرعات
+
+441
+00:33:06,250 --> 00:33:09,750
+متتالية من الـ human gonadotropin-releasing
+
+442
+00:33:09,750 --> 00:33:13,710
+hormone agonist خلال عملية induction الحدث
+
+443
+00:33:13,710 --> 00:33:17,010
+Inducing Stimulation Stimulation بنسميها induction
+
+444
+00:33:17,010 --> 00:33:22,730
+كمان هذا المصطلح بنسميه desensitization يعني
+
+445
+00:33:22,730 --> 00:33:28,650
+reduction in the response of receptor  receptor for
+
+446
+00:33:28,650 --> 00:33:31,970
+example gonadotropin-releasing hormone agonist are
+
+447
+00:33:31,970 --> 00:33:37,400
+type of medication that suppress ovulation by
+
+448
+00:33:37,400 --> 00:33:39,560
+stopping the production of estrogen and
+
+449
+00:33:39,560 --> 00:33:42,620
+progesterone الـ gonadotropin releasing hormone
+
+450
+00:33:42,620 --> 00:33:47,660
+agonist they had الـ advantage تبعته أنه عنده high
+
+451
+00:33:47,660 --> 00:33:51,560
+affinity for gonadotropin releasing hormone
+
+452
+00:33:51,560 --> 00:33:56,140
+receptor compared to native يعني أنا لو قارنت الـ
+
+453
+00:33:56,140 --> 00:34:02,710
+receptor لو قارنت الـ receptor قابليتها للارتباط مع الـ
+
+454
+00:34:02,710 --> 00:34:05,010
+agonist gonadotropin releasing hormone و لا 
+
+455
+00:34:05,010 --> 00:34:08,150
+الناتيف هتلاقي أن الـ gonadotropin releasing hormone
+
+456
+00:34:08,150 --> 00:34:12,030
+له قابلية للارتباط مع الـ receptor أكثر من 
+
+457
+00:34:12,030 --> 00:34:15,490
+الناتيف عشان كده له أفضلية they have greater
+
+458
+00:34:15,490 --> 00:34:19,290
+resistance to enzyme breakdown فطالما بيقاوم
+
+459
+00:34:19,290 --> 00:34:22,850
+التكسير بفعل الإنزيمات المحللة إذن هيبقى لفترة
+
+460
+00:34:22,850 --> 00:34:27,450
+زمنية طويلة جداً إذا فترة بقائه أكثر من فترة بقاء
+
+461
+00:34:27,450 --> 00:34:30,450
+الناتيف gonadotropin releasing hormone they have a
+
+462
+00:34:30,450 --> 00:34:34,930
+prolonged life half-life شو يعني طالما فترة بقائه
+
+463
+00:34:34,930 --> 00:34:39,690
+أطول وطالما بيقاوم إذا فترة بقائه أطول يعني الـ
+
+464
+00:34:39,690 --> 00:34:42,630
+half-life تبعته أطول من النتيجة هذه تُعتبر
+
+465
+00:34:42,630 --> 00:34:46,970
+advantage خاصة بالـ gonadotropin releasing hormone
+
+466
+00:34:46,970 --> 00:34:52,090
+بشكل عام الـ gonadotropin releasing hormone agonist
+
+467
+00:34:52,090 --> 00:34:59,220
+يجب أن تُعطى يجب أن تُعطى لمدة 10 إلى 15 يوم before
+
+468
+00:34:59,220 --> 00:35:02,100
+down regulation يعني قبل ما يصير الـ down
+
+469
+00:35:02,100 --> 00:35:06,240
+regulation السيدة بتكون ماخدة dose من الـ gonadotropin
+
+470
+00:35:06,240 --> 00:35:09,040
+releasing hormone agonist من 10 إلى 15
+
+471
+00:35:09,040 --> 00:35:16,720
+يوم علشان يصير عندي سرعة في استجابة الـ
+
+472
+00:35:16,720 --> 00:35:20,400
+anterior loop للبطنيوتر الغدة من أجل إخفاض مستوى الـ
+
+473
+00:35:20,400 --> 00:35:25,140
+FSH والـ LH يعني سرعة في الـ dropping الخاصة بالـ FSH
+
+474
+00:35:25,140 --> 00:35:29,510
+والـ LH نتيجة أو الخاصة بعمل ما يُعرف باسم 
+
+475
+00:35:29,510 --> 00:35:33,110
+Downregulation of antilipopapotatory gland لازم
+
+476
+00:35:33,110 --> 00:35:36,430
+أبدأ عملية الـ injection بالجناداتروبيين releasing
+
+477
+00:35:36,430 --> 00:35:40,390
+hormone في مرحلة الـ middle luteal phase أي ما يُعرف
+
+478
+00:35:40,390 --> 00:35:45,810
+في اليوم الـ 21 من الدورة السابقة إذا أنا في عندي 
+
+479
+00:35:45,810 --> 00:35:50,890
+احتمالين والثالث جاي في الطريقة الاحتمال الأول أن 
+
+480
+00:35:50,890 --> 00:35:55,570
+السيدة لازم يصير لها injection و induction بالـ
+
+481
+00:35:55,570 --> 00:35:58,830
+gonadotropin-releasing hormone agonist لمدة من 10
+
+482
+00:35:58,830 --> 00:36:02,510
+إلى 15 يوم قبل الـ down regulation علشان يصير
+
+483
+00:36:02,510 --> 00:36:06,950
+عندي down regulation سريع ببدأ في اليوم 21 من 
+
+484
+00:36:06,950 --> 00:36:11,510
+الدورة السابقة ببدأ في اليوم 21 من الدورة السابقة
+
+485
+00:36:11,510 --> 00:36:15,650
+it can also be started in the early follicular
+
+486
+00:36:15,650 --> 00:36:21,600
+phase في اليوم السادس أو اليوم الثالث عشر أيضاً بعد 
+
+487
+00:36:21,600 --> 00:36:26,340
+إنتاج
+
+488
+00:36:26,340 --> 00:36:33,840
+الـ anterior للبطنيوتر الغدة إنتاج
+
+489
+00:36:33,840 --> 00:36:34,320
+الإنتاج الإنتاج الإنتاج الإنتاج الإنتاج
+
+490
+00:36:34,320 --> 00:36:36,960
+الإنتاج الإنتاج الإنتاج الإنتاج الإنتاج
+
+491
+00:36:36,960 --> 00:36:37,020
+الإنتاج الإنتاج الإنتاج الإنتاج الإنتاج
+
+492
+00:36:37,020 --> 00:36:37,240
+الإنتاج الإنتاج الإنتاج الإنتاج الإنتاج
+
+493
+00:36:37,240 --> 00:36:41,560
+الإنتاج الإنتاج الإنتاج الإنتاج الإنتاج
+
+494
+00:36:41,560 --> 00:36:50,400
+الإنتاج الإنتاج الإنتاج الإنتاج الإنتاج الـ 
+
+495
+00:36:50,400 --> 00:36:54,820
+gonadotropin releasing hormone agonist كمية الإبرة
+
+496
+00:36:54,820 --> 00:36:59,100
+اللي بأعطيها حتى الوصول إلى مرحلة الـ ovulation
+
+497
+00:36:59,100 --> 00:37:06,720
+بأعطي FSH علشان يعمل نضوج للبويضة استعداداً للإباضة
+
+498
+00:37:06,720 --> 00:37:11,640
+استعداداً للـ ovulation طبعاً الـ dose of FSH required
+
+499
+00:37:11,640 --> 00:37:14,820
+may be different from one person to another person
+
+500
+00:37:14,820 --> 00:37:19,320
+يعني من 150 إلى 450 international unit per day
+
+501
+00:37:19,720 --> 00:37:24,500
+فبالتالي الـ FSH هو المسؤول عن عملية .. المسؤول عن
+
+502
+00:37:24,500 --> 00:37:29,680
+عملية الـ maturation of oocyte الـ maturation of
+
+503
+00:37:29,680 --> 00:37:34,520
+oocyte what is the side effect of gonadotropin
+
+504
+00:37:34,520 --> 00:37:37,320
+releasing hormone agonist؟ هل هو له side effect؟
+
+505
+00:37:37,320 --> 00:37:41,260
+أكيد له side effect لأن أنا بأعطي السيدة hormone
+
+506
+00:37:41,260 --> 00:37:44,900
+بأعطيها hormone exogenous hormone فبالتالي هيكون
+
+507
+00:37:44,900 --> 00:37:49,480
+عندها side effect منها hot flush أنها بقت من الحمة
+
+508
+00:37:50,630 --> 00:37:53,690
+في عندها dryness في الفاجينة، في عندها headache،
+
+509
+00:37:53,690 --> 00:37:58,310
+fatigue، في عندها sweating في مرحلة الليل، في 
+
+510
+00:37:58,310 --> 00:38:01,570
+عندها مشاكل في الـ mood، الـ mood غير متزن، أعصابية،
+
+511
+00:38:01,570 --> 00:38:06,390
+tension، قلقة، بتكون، في عندها decrease في الـ bone
+
+512
+00:38:06,390 --> 00:38:11,270
+mineral density عندها كثافة العظام لحد ما بتكون
+
+513
+00:38:11,270 --> 00:38:15,810
+قليلة أو تميل إلى عدم وجود mineral فيها، هذا 
+
+514
+00:38:15,810 --> 00:38:18,810
+المقصود فيها طبعاً الـ gonadotropin اللي لازم هرمون
+
+515
+00:38:18,810 --> 00:38:23,100
+agonist هذا كل اللي حكينا فيه عشر إلى خمس عشر يوم
+
+516
+00:38:23,100 --> 00:38:25,280
+وممكن أبدأ في اليوم الواحد والعشرين من الدورة
+
+517
+00:38:25,280 --> 00:38:28,420
+السابقة أو اليوم السادس من الدورة الحالية كلّه 
+
+518
+00:38:28,420 --> 00:38:31,500
+علاقة بالـ long protocol تعالوا شوفوا الـ short
+
+519
+00:38:31,500 --> 00:38:37,180
+protocol the continuous for a duration of two week
+
+520
+00:38:37,180 --> 00:38:41,800
+required patient to take a drug to stimulate the
+
+521
+00:38:41,800 --> 00:38:47,120
+ovaries for just five to nine days before a
+
+522
+00:38:47,120 --> 00:38:53,490
+collection rather than five4 to 5 days in long
+
+523
+00:38:53,490 --> 00:38:57,190
+protocol خذوا بالكم وبيقول هنا في الـ gonadotropin
+
+524
+00:38:57,190 --> 00:39:00,270
+releasing hormone agonist الـ long protocol بياخد 
+
+525
+00:39:00,270 --> 00:39:04,490
+خمس أسابيع الـ short protocol بياخد أسبوعين فقط
+
+526
+00:39:04,490 --> 00:39:09,450
+لغيره شوفت الفرق من خمس أسابيع لأسبوعين في الـ long
+
+527
+00:39:09,450 --> 00:39:15,460
+protocol خمس أسابيع خمس أسابيع يوم يوم هتأخذ الزوجة 
+
+528
+00:39:15,460 --> 00:39:20,020
+أو السيدة induction إبر حتى الوصول إلى مرحلة التفجير
+
+529
+00:39:20,020 --> 00:39:24,820
+والمقصود بالتفجير يعني الـ ovulation هذا في الـ long
+
+530
+00:39:24,820 --> 00:39:27,780
+في الـ short protocol و gonadotropin releasing hormone
+
+531
+00:39:27,780 --> 00:39:33,640
+agonist أسبوعين أسبوعين بتشمل الـ down regulation و
+
+532
+00:39:33,640 --> 00:39:39,120
+بتشمل الـ ovulation أيضاً فترة زمنية أقصر هنا صورة 
+
+533
+00:39:39,120 --> 00:39:43,920
+بتوضح الكلام اللي احنا حكينا من حيث عملية الـ 
+
+534
+00:39:43,920 --> 00:39:48,360
+duration لو أنا عندي هذا اليوم 21 من الدورة
+
+535
+00:39:48,360 --> 00:39:52,760
+السابقة الـ past cycle الـ past menstrual cycle
+
+536
+00:39:52,760 --> 00:39:59,640
+الدورة الحالية 1 لحد دي اليوم 11 وهو يوم التفجير 
+
+537
+00:39:59,640 --> 00:40:05,080
+أعتبره الـ long protocol بدأ من يوم الـ long
+
+538
+00:40:05,080 --> 00:40:11,230
+protocol بدأ من يوم 21 من الدورة السابقة فاخذ عندي
+
+539
+00:40:11,230 --> 00:40:17,110
+21 و 22 و 23 و 24 و 25 و 26 و 27 و 28 تمام أيام من الدورة 
+
+540
+00:40:17,110 --> 00:40:21,550
+السابقة وكمان أخذ عشر أيام من الدورة الحالية يعني
+
+541
+00:40:21,550 --> 00:40:27,030
+ما يقارب 18 يوم يعني تقريباً تلات أسابيع هذا بيسموه 
+
+542
+00:40:27,030 --> 00:40:31,930
+long protocol الـ short protocol بدأ فقط لغير من 
+
+543
+00:40:31,930 --> 00:40:38,810
+اليوم مثلاً الثالث من الدورة الحالية لحد دي عشر أيام
+
+544
+00:40:38,810 --> 00:40:44,390
+يعني تقريباً أسبوع إلا شوية الـ ultra short ما بياخد 
+
+545
+00:40:44,390 --> 00:40:48,310
+فترة زمنية طويلة جداً في الـ stimulation ما بياخد 
+
+546
+00:40:48,310 --> 00:40:51,970
+فترة زمنية طويلة جداً في الـ stimulation هذه الفرق
+
+547
+00:40:51,970 --> 00:40:56,370
+بين الـ long و الـ short و الـ ultra short الـ started
+
+548
+00:40:56,370 --> 00:41:01,010
+point وين هل الـ 21 من الدورة السابقة و لا اليوم
+
+549
+00:41:01,010 --> 00:41:07,480
+الأول من الدورة السابقة و لا اليوم السادس من الدورة
+
+550
+00:41:07,480 --> 00:41:12,520
+الحالية هذه اللي احنا بنحكي عنها ايش الفرق ما بين
+
+551
+00:41:12,520 --> 00:41:17,020
+الـ long و الـ short protocol خلينا نشوف الـ short 
+
+552
+00:41:17,020 --> 00:41:21,280
+protocol شو هو بناء على الفيديو وبعدين ننتقل لـ
+
+553
+00:41:21,280 --> 00:41:26,980
+long protocol كمقارنة بسيطة في الأيام الأولى من 
+
+554
+00:41:26,980 --> 00:41:30,500
+المدرسة، تم التحقق من مدرسة الـ endometrium من مصفحة
+
+555
+00:41:30,500 --> 00:41:34,100
+الـ hCG والتعامل مع الموجودة من السيستات في
+
+556
+00:41:34,100 --> 00:41:38,120
+الـ Racin
+
+557
+00:41:38,120 --> 00:41:44,620
+إذا
+
+558
+00:41:44,620 --> 00:41:48,500
+كانت كل شيء عادي، يتم تحقيق الـ GnRH-Analog Agonist 
+
+559
+00:41:49,720 --> 00:41:54,820
+1 أو 2 أيام لاحقاً تبدأ استخدام الهرمون FSH في
+
+560
+00:41:54,820 --> 00:42:01,200
+اليوم اليوم اليوم يومي
+
+561
+00:42:01,200 --> 00:42:02,860
+يومي يومي يومي يومي يومي يومي
+
+562
+00:42:06,690 --> 00:42:10,030
+في نهاية أقل من 4 إلى 6 أيام من التدخل، يتم تجريبها
+
+563
+00:42:10,030 --> 00:42:13,690
+مرة أخرى لتحقق من رقمها ومجموعتها من الفوليكولات
+
+564
+00:42:13,690 --> 00:42:18,130
+ومجموعتها من الاندومتريا كل 2 أو 3 أيام، يتم تجريبها 
+
+565
+00:42:18,130 --> 00:42:21,050
+مرة أخرى لتحقيق الـ Ultrasound عندما تكون أقل من 3
+
+566
+00:42:21,050 --> 00:42:26,350
+فوليكولات أكبر إلى أقل من 18 ميليمتر، يتم تحريكها
+
+567
+00:42:26,350 --> 00:42:28,770
+بالهورمون HCG
+
+568
+00:42:32,660 --> 00:42:35,500
+Oocyte recovery is undertaken 36 hours later.
+
+569
+00:42:35,960 --> 00:42:38,640
+Following the procedure, daily administration of
+
+570
+00:42:38,640 --> 00:42:41,720
+the hormone progesterone is given vaginally. Two
+
+571
+00:42:41,720 --> 00:42:44,560
+to five days after oocyte recovery, the embryos
+
+572
+00:42:44,560 --> 00:42:48,020
+are transferred. Two weeks later, a pregnancy test
+
+573
+00:42:48,020 --> 00:42:52,580
+is performed طبعا هنا بتحكي عن شغلة، شايفين هنا في 
+
+574
+00:42:52,580 --> 00:42:55,060
+عيني، سماها gonadotropin-releasing hormone
+
+575
+00:42:55,060 --> 00:42:59,680
+Analogues بعدين أعطى الـ FSH اللي بتعمل stimulation
+
+576
+00:42:59,680 --> 00:43:04,400
+و induction ولما وصلت الفولك الـ 18 ميلي متر وهي
+
+577
+00:43:04,400 --> 00:43:07,980
+عبارة عن الـ .. الـ .. الـ diameter المسموح بعملية 
+
+578
+00:43:07,980 --> 00:43:12,980
+الإباضة أعطى ما يُعرف الـ hCG وهو عبارة عن human
+
+579
+00:43:12,980 --> 00:43:17,220
+chorionic gonadotropin ولكن recombinant وعمله يشبه
+
+580
+00:43:17,220 --> 00:43:21,780
+عمل الـ LH وهو عبارة عن الـ ovulation بعد كده أعطى
+
+581
+00:43:21,780 --> 00:43:25,560
+الـ progesterone بعد عملية الـ embryo transfer من أجل
+
+582
+00:43:25,560 --> 00:43:28,820
+تثبيت عملية الحمل إن وجدت
+
+583
+00:43:37,790 --> 00:43:41,790
+هذا الـ long protocol طبعا بدأ من long protocol
+
+584
+00:43:41,790 --> 00:43:47,190
+هيبدأ من اليوم رقم 21 من الدورة السابقة وصولا إلى 
+
+585
+00:43:47,190 --> 00:43:51,350
+اليوم 13 أو 12 لعملية الإباضة بعد كده الـ
+
+586
+00:43:51,350 --> 00:43:58,120
+embryo transfer و خلافه الـ GnRH-Analog antagonist يتم
+
+587
+00:43:58,120 --> 00:44:01,820
+استخدامه بشكل نسبي أو بشكل أساسي من اليوم الـ 21
+
+588
+00:44:01,820 --> 00:44:02,000
+من عملية عملية عملية عملية عملية عملية الـ
+
+589
+00:44:02,000 --> 00:44:05,780
+Menstrual Cycle. بالتالي، بسبب تأثير الـ LH الأول،
+
+590
+00:44:05,780 --> 00:44:09,480
+تم إطلاق الـ Pituitary للـ LH والذلك يقوم بتحرير
+
+591
+00:44:09,480 --> 00:44:09,980
+عملية عملية عملية عملية عملية العملية الـ LH بشكل
+
+592
+00:44:09,980 --> 00:44:10,400
+أساسي لتحرير عملية عملية عملية عملية العملية
+
+593
+00:44:10,400 --> 00:44:11,640
+العملية العملية العملية العملية العملية
+
+594
+00:44:11,640 --> 00:44:11,980
+العملية العملية العملية العملية العملية
+
+595
+00:44:11,980 --> 00:44:13,140
+العملية العملية العملية العملية العملية
+
+596
+00:44:13,140 --> 00:44:17,360
+العملية العملية العملية في وقت الاستعمال، يتم إعطاء
+
+597
+00:44:17,360 --> 00:44:21,760
+صورة لتحقق أضعف الـ Endometrium في المخزون الدوري،
+
+598
+00:44:21,760 --> 00:44:31,080
+ويقوم بإدخال موجودة من الـ Cysts في الأعضاء. إذا
+
+599
+00:44:31,080 --> 00:44:36,220
+كانت كل شيء عاديًا، يتم إدخال تدخلات FSH بسرعة
+
+600
+00:44:36,220 --> 00:44:38,650
+أساسية. هذا الهرمون يساعد على اكتشاف عبارة عن عبارة
+
+601
+00:44:38,650 --> 00:44:38,990
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+602
+00:44:38,990 --> 00:44:39,650
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+603
+00:44:39,650 --> 00:44:40,950
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+604
+00:44:40,950 --> 00:44:42,770
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+605
+00:44:42,770 --> 00:44:49,290
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+606
+00:44:49,290 --> 00:44:49,910
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+607
+00:44:49,910 --> 00:44:52,990
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+608
+00:44:52,990 --> 00:44:56,370
+عبارة
+
+609
+00:44:56,370 --> 00:44:58,430
+عن عب
+
+610
+00:45:00,760 --> 00:45:04,840
+كل 2 أو 3 أيام يتم تجريب جرس جديد، عندما يكون أقل
+
+611
+00:45:04,840 --> 00:45:08,960
+من 3 فوليكولات أكبر إلى أقل من 18 ميلي متر. أخيرًا،
+
+612
+00:45:08,960 --> 00:45:14,400
+تشغيل مادة الفوليكولات مع هرمون HCG، الفوليكولات
+
+613
+00:45:14,400 --> 00:45:16,960
+الموجودة داخل الفوليكولات ستبدأ في التطور. التجارب
+
+614
+00:45:16,960 --> 00:45:21,860
+الأمريكية تتم 36 ساعات لاحقًا، وبالتالي، يتم
+
+615
+00:45:21,860 --> 00:45:24,300
+إعادة الهرمون البروجيسترون. يتم إعادة الهرمون 
+
+616
+00:45:24,300 --> 00:45:27,720
+البروجيسترون بشكل مهبلي، و2 إلى 5 أيام بعد التعامل
+
+617
+00:45:27,720 --> 00:45:29,460
+مع الـ Oocyte، يتم إعادة التعامل مع الهرمون
+
+618
+00:45:29,460 --> 00:45:31,020
+البروجيسترون بشكل مهبلي، و2 أيام لاحقًا، يتم إعادة 
+
+619
+00:45:31,020 --> 00:45:34,730
+التعامل مع الهرمون البروجيسترون بشكل مهبلي. في كل
+
+620
+00:45:34,730 --> 00:45:37,310
+المرحلة من البداية حتى النهاية من مرحلة الـ
+
+621
+00:45:37,310 --> 00:45:41,970
+induction حتى مرحلة الـ beta hCG analysis أنا بحكي 
+
+622
+00:45:41,970 --> 00:45:45,030
+على الـ long protocol تحت مصطلح gonadotropin
+
+623
+00:45:45,030 --> 00:45:48,690
+-releasing hormone analogues agonist أعطاها في
+
+624
+00:45:48,690 --> 00:45:52,290
+اليوم الـ 21 من الدورة السابقة من أجل تحفيز الـ
+
+625
+00:45:52,290 --> 00:45:54,870
+hypothalamic pituitary loop للـ Pituitary gland لإنتاج الـ FSH
+
+626
+00:45:54,870 --> 00:45:57,770
+والـ LH بعد كده عملها dropping أو down أو 
+
+627
+00:45:57,770 --> 00:46:02,340
+shutdown أو down regulation فبطلت تفرز. بعد كده عمل
+
+628
+00:46:02,340 --> 00:46:06,900
+عملية scanning للـ ovary شاف الـ endometrium أو
+
+629
+00:46:06,900 --> 00:46:11,100
+بطانة الرحم نمت بشكل .. في استجابة ولا لأ؟ إذا وجد
+
+630
+00:46:11,100 --> 00:46:13,600
+في استجابة هيبدأ يعطيها الـ recombinant FSH
+
+631
+00:46:13,600 --> 00:46:19,280
+حتى اليوم الـ 12 كل تلات أيام أو كل يومين بصور بشوف
+
+632
+00:46:19,280 --> 00:46:25,290
+وضع المبيض كيف هو؟ هل استجاب لهرمون علشان يظبط
+
+633
+00:46:25,290 --> 00:46:28,110
+الدوز؟ ممكن في بعض الأحيان نلاقي الاستجابة سريعة
+
+634
+00:46:28,110 --> 00:46:31,750
+فبيقلل الدوز. الاستجابة بطيئة فبيزود الدوز. الطبيب
+
+635
+00:46:31,750 --> 00:46:35,030
+هذا من خلال حاجة بنسميها الـ E2 level والـ
+
+636
+00:46:35,030 --> 00:46:39,430
+Estrogen يعني و تصوير الرحم مع تصوير المبيض و
+
+637
+00:46:39,430 --> 00:46:43,050
+الفوليكل. إذا الفوليكل عدد من الفوليكولات أقل شيء
+
+638
+00:46:43,050 --> 00:46:46,550
+تلاتة فوليكولات وصلوا إلى الـ Diameter المطلوب 18
+
+639
+00:46:46,550 --> 00:46:50,990
+Millimeter يعني معناه فيه mature oocyte. هيعطيها 
+
+640
+00:46:50,990 --> 00:46:54,570
+للزوجة ما يُعرف باسم أو للسيدة ما يُعرف باسم الـ 
+
+641
+00:46:54,570 --> 00:46:59,850
+Recombinant hCG الذي يعمل عملية الإباضة. بعد
+
+642
+00:46:59,850 --> 00:47:03,750
+كده بيصير puncture أنه بيعمل aspiration للـ oocyte
+
+643
+00:47:03,750 --> 00:47:07,430
+بعدين بيعملها تلقيح. بعد يومين تلاتة بيعمل embryo
+
+644
+00:47:07,430 --> 00:47:11,170
+transfer وبعد أسبوعين بيعمل pregnancy test علشان
+
+645
+00:47:11,170 --> 00:47:14,490
+نشوف الـ beta hCG قد إيش الـ level تبعها ولكن بعد ما
+
+646
+00:47:14,490 --> 00:47:18,230
+يعمل embryo transfer لازم يعطي الـ progesterone علشان
+
+647
+00:47:18,230 --> 00:47:22,490
+يزيد من تثبيت و الـ implantation rate اللي احنا 
+
+648
+00:47:22,490 --> 00:47:26,730
+بنسميها حبوب التثبيت أو أقراص التثبيت هي عبارة عن 
+
+649
+00:47:26,730 --> 00:47:32,250
+هرمون الـ progesterone. هذه فكرة الـ long protocol و
+
+650
+00:47:32,250 --> 00:47:35,610
+short protocol المتعلق بالـ gonadotropin releasing 
+
+651
+00:47:35,610 --> 00:47:40,030
+hormone agonist. so what is the advantage of short
+
+652
+00:47:40,030 --> 00:47:43,650
+protocol؟ الـ advantage of short protocol إن أنا ما
+
+653
+00:47:43,650 --> 00:47:48,070
+بجهد. أفضل الـ advantage of short protocol أول شغلة
+
+654
+00:47:48,290 --> 00:47:51,050
+إن أنا بيصير عندي reduction في الـ chance of a
+
+655
+00:47:51,050 --> 00:47:55,430
+premature and low birth weight baby بيصير عندي
+
+656
+00:47:55,430 --> 00:47:58,490
+reduction في الـ risk of ovarian hyperstimulation
+
+657
+00:47:58,490 --> 00:48:03,590
+syndrome. بيصير أكثر تركيزا على البويضات الناضجة
+
+658
+00:48:03,590 --> 00:48:08,170
+لوحدها بشكل طبيعي ولكن تحتاج إلى تدقيم قليل لأن في
+
+659
+00:48:08,170 --> 00:48:11,310
+بويضات بتكون ناضجة طبيعي ولكن تحتاج إلى dose بسيطة
+
+660
+00:48:11,310 --> 00:48:16,030
+علشان تنضج وتنمو فهذه بتكون الـ quality تبعتها جيدة
+
+661
+00:48:16,030 --> 00:48:19,900
+جدا، بتكون mature و high quality. It is more
+
+662
+00:48:19,900 --> 00:48:24,860
+inexpensive because we used low dose of medication
+
+663
+00:48:24,860 --> 00:48:27,980
+reducing the cost of treatment. يعني فيه علاقة بالـ
+
+664
+00:48:27,980 --> 00:48:31,700
+quality of mature oocyte. فيه علاقة بانخفاض معدل
+
+665
+00:48:31,700 --> 00:48:37,120
+حدوث الـ premature baby. فيه علاقة بانخفاض معدل حدوث
+
+666
+00:48:37,120 --> 00:48:40,520
+الـ ovarian hyperstimulation syndrome. بالإضافة إلى
+
+667
+00:48:40,520 --> 00:48:45,780
+أن تكلفته قليلة إلى حد ما. سوف نكتفي بهذا القدر في
+
+668
+00:48:45,780 --> 00:48:50,230
+محاضرة اليوم، على أمل أن نلتقي في محاضرات قادمة إن 
+
+669
+00:48:50,230 --> 00:48:50,770
+شاء الله
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/UpgBJG4XVfA_postprocess.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/UpgBJG4XVfA_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..691801886101dbab62f19f3f831b87c00880b88e
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/UpgBJG4XVfA_postprocess.srt
@@ -0,0 +1,2676 @@
+1
+00:00:00,000 --> 00:00:05,240
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,240 --> 00:00:11,080
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا
+
+3
+00:00:11,080 --> 00:00:15,240
+الأعزاء نرجو من الله الكريم أن تكونوا جميعا بخير
+
+4
+00:00:15,240 --> 00:00:21,760
+وبصحة جيدة اليوم سوف ننتقل إلى مربع جديد يعتبر جزء
+
+5
+00:00:21,760 --> 00:00:27,130
+أساسيا من عمليات الحقن المجهريوالذي سوف يتحدث عن
+
+6
+00:00:27,130 --> 00:00:31,050
+تحفيز المبيض لدى السيدات تحت مصطلح stimulation
+
+7
+00:00:31,050 --> 00:00:35,490
+protocol ثم ننتقل إلى أنواع ال media التي تستخدم
+
+8
+00:00:35,490 --> 00:00:40,030
+من أجل انضاج البوايضة إذا كانت البوايضة غير ناضجة
+
+9
+00:00:40,030 --> 00:00:45,590
+لحظة السحب أو وضع البوايضة المخصبة في media معينة
+
+10
+00:00:45,590 --> 00:00:51,710
+بناء على أيام انقسامها عملية stimulation protocol
+
+11
+00:00:51,710 --> 00:00:57,310
+مهمة جدا في عمليات الحقن المجهريومن خلال عملية
+
+12
+00:00:57,310 --> 00:01:02,830
+تحفيظ المبيض نصل إلى عدد معين من البويضات التي
+
+13
+00:01:02,830 --> 00:01:07,870
+ينبغي أن تكون ناضجة وينبغي أن تكون صالح للإخصاد
+
+14
+00:01:07,870 --> 00:01:12,890
+بأن تكون تحتوي على first polar body اليوم سوف
+
+15
+00:01:12,890 --> 00:01:18,010
+نتحدث عن هذه البروتوكولات المختلفة وكيف وما هي وما
+
+16
+00:01:18,010 --> 00:01:23,490
+اختلاف ما بين هذه البروتوكولات في البدايةفي بدايات
+
+17
+00:01:23,490 --> 00:01:27,730
+عملية التلقيح الصناعي أو عملية التلقيح الصناعي
+
+18
+00:01:27,730 --> 00:01:32,770
+المعترف بيها اسم In vitro fertilization يعني أطفال
+
+19
+00:01:32,770 --> 00:01:38,530
+النبيب كان هناك حالات يحدث فيها حمل ولكن من أجل
+
+20
+00:01:38,530 --> 00:01:44,390
+زيادة فرصة نجاح عملية التلقيح الصناعي وزيادة فرصة
+
+21
+00:01:44,390 --> 00:01:49,370
+وجود حمل ونجاح عملية التلقيح يجب علينا أن نصل إلى
+
+22
+00:01:49,370 --> 00:01:53,790
+مرحلةوهي مرحلة الحصول على أكبر عدد من البويضات
+
+23
+00:01:53,790 --> 00:02:00,090
+النادجة من أجل ضمان إلى حد ما نجاح عملية الحقن أو
+
+24
+00:02:00,090 --> 00:02:07,130
+التلقيح الصناعي فبالتالي من أجل تحسين عملية الحقن
+
+25
+00:02:07,130 --> 00:02:13,090
+ومن أجل تحسين معدل الحقن ومن أجل تحسين معدلحدوث
+
+26
+00:02:13,090 --> 00:02:18,810
+عملية الحمل pregnancy rate يجب علينا أن نسحب ونجمع
+
+27
+00:02:18,810 --> 00:02:23,490
+أكبر عدد من البويضات الناضجة التي تكون صالحة
+
+28
+00:02:23,490 --> 00:02:27,250
+لعملية الإخصاد فالبويضة الناضجة تكون صالحة لعملية
+
+29
+00:02:27,250 --> 00:02:31,790
+الإخصاد إذا كانت على شكل بويضة تحتوي على fairest
+
+30
+00:02:31,790 --> 00:02:36,510
+polar body فهذه العملية التي يتم من خلال تحسين
+
+31
+00:02:36,510 --> 00:02:42,160
+وزيادة عدد البويضات المسعوبة يتم من خلالحث المبيض
+
+32
+00:02:42,160 --> 00:02:47,740
+على إنتاج أكبر عدد من خلال تحفيزه بهرمونات خارجية
+
+33
+00:02:47,740 --> 00:02:52,560
+أو داخلية تشبه الهرمونات التي تعمل على المبيض من
+
+34
+00:02:52,560 --> 00:02:55,520
+أشهر الهرمونات التي تعمل على المبيض بناء على ما
+
+35
+00:02:55,520 --> 00:03:01,580
+دراسنا ال FSH و ال LH فبالتالي أنا كإنسان بشتغل في
+
+36
+00:03:01,580 --> 00:03:05,840
+ال emperiologist بدي أعمل تحفيز للمبيض و غادر طبعا
+
+37
+00:03:05,840 --> 00:03:08,400
+الطبيب هو اللي بحدد ال dose بناء على ال history
+
+38
+00:03:08,400 --> 00:03:13,330
+باستخدامExogenous أو Endogenous هرمون في الغالب
+
+39
+00:03:13,330 --> 00:03:17,770
+بيكون FSH في الغالب بيكون FSH أو ما يُعرف باسم
+
+40
+00:03:17,770 --> 00:03:22,550
+Gonadotropin والـ Gonadotropin هما نوعين FSH و LH
+
+41
+00:03:22,550 --> 00:03:27,790
+خلال السنوات المتعاقبة التي تتعلق بعمليات الحقن
+
+42
+00:03:27,790 --> 00:03:31,670
+المجهري والتلقيح الصناعيوجد هناك العديد من ال
+
+43
+00:03:31,670 --> 00:03:35,670
+protocolات التي يمكن استخدامها وكل ال protocol له
+
+44
+00:03:35,670 --> 00:03:39,270
+advantage و له disadvantage فلا يمكن استخدام
+
+45
+00:03:39,270 --> 00:03:43,290
+protocol واحد لجميع السيدات فبالتالي كل حالة
+
+46
+00:03:43,290 --> 00:03:48,070
+مستقلة عن الأخرى ولها protocol خاص فيها أول من
+
+47
+00:03:48,070 --> 00:03:52,590
+استخدم عملية ال protocols وعملية تحفيز المبيض كان
+
+48
+00:03:52,590 --> 00:03:58,190
+Porterزملاءه هما استخدموا ما يسمى الـ Gonadotropin
+
+49
+00:03:58,190 --> 00:04:02,650
+Releasing Hormone Agonist في عملية الـ IV Epi
+
+50
+00:04:02,650 --> 00:04:07,350
+Treatment فهو أول من استخدم عملية حقن السيدات
+
+51
+00:04:07,350 --> 00:04:13,130
+بغرمونات خارجية من أجل تحفيز المبيض تحت مصطلح GnRa
+
+52
+00:04:13,130 --> 00:04:17,790
+Agonist أي Gonadotropin Releasing Hormone Agonist
+
+53
+00:04:17,790 --> 00:04:22,730
+هذا كان أول واحد فيما يلي تعاقبة الأحداث وتتاليت
+
+54
+00:04:23,160 --> 00:04:27,520
+وتم تطوير قعدة البروتوكولات تقليديًا تطوير عدد
+
+55
+00:04:27,520 --> 00:04:32,420
+مرتبط أوسايت كان ممكنًا فقط بعد تطوير التحكم
+
+56
+00:04:32,420 --> 00:04:37,900
+التسلسلي أوفريانية بمعنى آخر يمكن للسيدة أن تعطي
+
+57
+00:04:37,900 --> 00:04:41,700
+عدد كبير جدًا من البويضات أكبر من الوضع الطبيعي
+
+58
+00:04:41,700 --> 00:04:45,480
+جعلنا في الوضع الطبيعي واحدة تنتين تلاتة بويضة
+
+59
+00:04:45,480 --> 00:04:50,580
+بينما إذا خضعت لمصطلح يسمى COS وهو عبارة عن
+
+60
+00:04:50,580 --> 00:04:54,740
+Controlled Ovarian Stimulationحطيط عدد كبير من
+
+61
+00:04:54,740 --> 00:05:00,000
+البوايدات قد يصل إلى 25 بوايدة وبعض الحالات تصل
+
+62
+00:05:00,000 --> 00:05:05,100
+إلى 35 بوايدة طبعا للأسف كلهم مش ناضج ولكن أقل شئ
+
+63
+00:05:05,100 --> 00:05:09,460
+تلتينه بيكون ناضجين شو يعني Controlled Ovarian
+
+64
+00:05:09,460 --> 00:05:12,680
+Hyperstimulation Protocol؟ هو عبارة عن نظام
+
+65
+00:05:12,680 --> 00:05:17,540
+وبروتوكول يستخدم فيه هرمونات تعمل على تحفيز المبيض
+
+66
+00:05:17,810 --> 00:05:22,350
+ولكن تحت عملية السيطرة ما بيغرد المبرة .. المبية
+
+67
+00:05:22,350 --> 00:05:26,450
+تخرج السرب و بيصير يشتغل من تلقاء نفسه ما بيصير
+
+68
+00:05:26,450 --> 00:05:32,670
+عندي hyper response لأ ال response بيكون محكم ..
+
+69
+00:05:32,670 --> 00:05:37,970
+انا ك technologist او ك imperialist متحكم فيه بناء
+
+70
+00:05:37,970 --> 00:05:41,870
+على ال dose اللي بعطيها للسيدة طبعا في الوضع
+
+71
+00:05:41,870 --> 00:05:46,460
+الطبيعي و في الدورة الشهرية الطبيعية تنموعدت من
+
+72
+00:05:46,460 --> 00:05:51,280
+الـAnterior Follicle الموجودة في المبيض ولكن ما
+
+73
+00:05:51,280 --> 00:05:55,540
+يصل إلى الـGrafian Follicle وهي لحظة الـ ovulation
+
+74
+00:05:55,540 --> 00:05:59,460
+واحدة، اتن، تلاتة ماكسيما الـ interaction between
+
+75
+00:05:59,460 --> 00:06:03,040
+growing follicle and pituitary gland and
+
+76
+00:06:03,040 --> 00:06:06,620
+hypothalamus prevented multifollicle growth and
+
+77
+00:06:06,620 --> 00:06:10,140
+allowed only one follicle complete maturation and
+
+78
+00:06:10,140 --> 00:06:13,400
+arrive to the stage of ovulation إيش اللي بيخلي
+
+79
+00:06:13,630 --> 00:06:16,790
+المبيض في الوضع الطبيعي ما بيطلّع أكتر من تلت
+
+80
+00:06:16,790 --> 00:06:20,350
+بويضات أو بويضتين كحد أقصى إنه في عندي نوع من
+
+81
+00:06:20,350 --> 00:06:23,370
+أنواع ال correlation نوع من أنواع ال interaction
+
+82
+00:06:23,370 --> 00:06:27,850
+نوع من أنواع ال connection ما بين ال hypothalamus
+
+83
+00:06:27,850 --> 00:06:32,230
+كmaster و ال pituitary gland التي تفرز الأفسح
+
+84
+00:06:32,230 --> 00:06:36,590
+والأدش و ال growing follicle فهذه الهرمونات اللي
+
+85
+00:06:36,590 --> 00:06:40,140
+بتكون رايحة جاية بين التلت مناطق هذههي اللي بتتحكم
+
+86
+00:06:40,140 --> 00:06:43,340
+في عمل المبيض و بتقول المبيض يكفي إنتاج بوايض
+
+87
+00:06:43,340 --> 00:06:47,960
+تانية أو ثلاثة كحد أقصى في الوضع الطبيعي لأن هذا
+
+88
+00:06:47,960 --> 00:06:52,020
+شغل هرمونات كل ما زاد هرمون ال FSH كل ما زاد معدل
+
+89
+00:06:52,020 --> 00:06:57,840
+نضوج البوايض و هكذا فبالتالي control ovarian
+
+90
+00:06:57,840 --> 00:07:02,100
+stimulation required multiply tele injection and
+
+91
+00:07:02,100 --> 00:07:05,620
+frequently monitoring scanning that creating
+
+92
+00:07:05,620 --> 00:07:08,580
+directly and indirectly caused lose of working
+
+93
+00:07:08,580 --> 00:07:14,280
+timeللأسف وجدوا أن عملية تحفيظ المبيض المتحكم به
+
+94
+00:07:14,280 --> 00:07:18,460
+مسمى Control Ovarian Hyper Stimulation يتم من خلال
+
+95
+00:07:18,460 --> 00:07:23,400
+إعطاء الزوجة أو إعطاء السيدة جرعات متتالية ويومية
+
+96
+00:07:23,400 --> 00:07:28,460
+من الهرمونات بشكل متتالي تكون هذه الجرعات تحت
+
+97
+00:07:28,460 --> 00:07:32,720
+السيطرة وتحت المراقبة بالإضافة إلى مراقبة وظهر
+
+98
+00:07:32,720 --> 00:07:37,320
+المبيضو الـ Diameter الخاصة بالفوليكيد ولكن للأسف
+
+99
+00:07:37,320 --> 00:07:40,860
+وجدوا أن هذه العملية عملية بالشكل العام متعبة
+
+100
+00:07:40,860 --> 00:07:47,880
+مرهقة مكلفة إضافة إلى أنها مضيعة للوقت في النظام
+
+101
+00:07:47,880 --> 00:07:52,240
+العالمي اللي يعتمد على أن الشخص يشتغل 8 ساعات
+
+102
+00:07:52,240 --> 00:07:56,120
+يوميا أو 9 ساعات يوميا فإذا هذه السيدة كانت عاملة
+
+103
+00:07:56,120 --> 00:08:00,280
+تشتغل في وظيفة معينة فبدت تخضع لل control of
+
+104
+00:08:00,280 --> 00:08:04,910
+various stimulationمن الراحة إلى حد ما عدم الإجهاد
+
+105
+00:08:04,910 --> 00:08:08,350
+فبالتالي هتخسر من ساعات أو هتقلل من ساعات دوامها
+
+106
+00:08:08,350 --> 00:08:12,190
+فبالتالي الإنتاج بتأثر عشان كده قالوا إنه يؤثر على
+
+107
+00:08:12,190 --> 00:08:18,430
+عدد ساعات العمل بشكل مباشر أو غير مباشر ولكن
+
+108
+00:08:18,430 --> 00:08:22,970
+المشكلة الأساسية هي مشكلة مادية فوجدوا إن الناس
+
+109
+00:08:22,970 --> 00:08:26,510
+والسيدات اللي بتخضع لدى ال protocol بدفع كميات
+
+110
+00:08:26,510 --> 00:08:30,960
+مهولة من الأموال فبالتالي بتكون عندى عبق ماليعلى
+
+111
+00:08:30,960 --> 00:08:35,560
+هذه العائلة The most important medical problem
+
+112
+00:08:35,560 --> 00:08:39,480
+associated with control ovarian stimulation is the
+
+113
+00:08:39,480 --> 00:08:43,940
+risk for ovarian hyperstimulation syndrome رسك
+
+114
+00:08:43,940 --> 00:08:48,760
+الخطير أو خلّيني أقول إن المعضلة الخطيرة اللي ممكن
+
+115
+00:08:48,760 --> 00:08:54,180
+تظهر عند هؤلاء السيداتاللواتي يخضعنا إلى الـ
+
+116
+00:08:54,180 --> 00:08:59,400
+Control Ovarian Stimulation عفوا ممكن يصير عندهم
+
+117
+00:08:59,400 --> 00:09:03,940
+حالة سميتها قبل شوية Hyper Stimulation ولكن إن ظهر
+
+118
+00:09:03,940 --> 00:09:08,140
+عليهم symptoms بسميها في هذه الحالة Ovarian Hyper
+
+119
+00:09:08,140 --> 00:09:12,640
+Stimulation Syndrome وحنتكلم عنها باستفادة في الشق
+
+120
+00:09:12,640 --> 00:09:15,480
+التاني من المحاضرة الـ Ovarian Hyper Stimulation
+
+121
+00:09:15,480 --> 00:09:18,460
+Syndrome تتميز إن في عندي enlargement في الـ Ovary
+
+122
+00:09:18,460 --> 00:09:24,380
+زيادة في blood capillaryPermeability بالإضافة إلى
+
+123
+00:09:24,380 --> 00:09:29,100
+shifting للـ fluid داخل الـ space المحيط بالـ
+
+124
+00:09:29,100 --> 00:09:33,920
+abdominal المحيط بالـ ovary طبعاً، this result
+
+125
+00:09:33,920 --> 00:09:37,980
+يؤدى إلى تكوين ما يُعرف باسم hypovolemia بيؤدى إلى
+
+126
+00:09:37,980 --> 00:09:40,980
+تكوين hemoconcentration بيؤدى إلى تكوين
+
+127
+00:09:40,980 --> 00:09:43,480
+hypercoagulopathy
+
+128
+00:09:45,660 --> 00:09:49,940
+high bar coagulability هنتكلم عنها باستفادة كيف
+
+129
+00:09:49,940 --> 00:09:55,280
+ممكن يصير عندك high bar في ال coagulation ال OHSS
+
+130
+00:09:55,280 --> 00:10:01,260
+maybe have some complicated like acute renal
+
+131
+00:10:01,260 --> 00:10:09,380
+failure, hypovolemic shock, thrombosis
+
+132
+00:10:13,940 --> 00:10:19,840
+في عندي مشاكل في الجهاز التنفسي بالاضافة إلى أنه
+
+133
+00:10:19,840 --> 00:10:24,780
+قد يكون قاتل شو يعني قد يكون قاتل؟ اه قد يكون قاتل
+
+134
+00:10:24,780 --> 00:10:31,620
+ال OHSS اللي لم يعالج هيكون يؤدي بالوفاة للسيدات
+
+135
+00:10:31,620 --> 00:10:35,260
+مصابين فيه طبعا انا مش هستفيد في هذا الموضوع ولكن
+
+136
+00:10:35,260 --> 00:10:39,780
+كانت علاج بسيطهنعرف كيف بيكون قاتل بناء على ال
+
+137
+00:10:39,780 --> 00:10:44,560
+severity الخاصة فيه ال risk for OHSS can be high
+
+138
+00:10:44,560 --> 00:10:49,180
+as 6% in young women with the polycystic ovarian
+
+139
+00:10:49,180 --> 00:10:52,600
+syndrome طبعا ال polycystic ovarian syndrome حالة
+
+140
+00:10:52,600 --> 00:10:58,420
+مرضية تختلف عن ال OHSS ال polycystic ovarian
+
+141
+00:10:58,420 --> 00:11:03,100
+syndrome قد تؤدي إلى إعاقة الحمل بسبب وجود تكييسات
+
+142
+00:11:03,100 --> 00:11:08,310
+حول المبيض أو تكييساتفي المبيعات هذا مرض يختلف عن
+
+143
+00:11:08,310 --> 00:11:12,390
+المرض الآخر اسمه ovarian hyperstimulation syndrome
+
+144
+00:11:12,390 --> 00:11:15,830
+PCOS
+
+145
+00:11:15,830 --> 00:11:20,270
+ممكن يحدث بشكل طبيعي هذا بيحدث بفعل effect أو
+
+146
+00:11:20,270 --> 00:11:26,470
+influence factor زي ال exogenous hormone طيب كيف
+
+147
+00:11:26,470 --> 00:11:30,970
+يمكن تحضير الذأسية و إعطائها بعض الأنواع من
+
+148
+00:11:30,970 --> 00:11:34,150
+الأتوية التي يمكن أن تستخدم في تحفيز المبيعات؟
+
+149
+00:11:35,730 --> 00:11:40,570
+Controlled Ovarian Hyperstimulation كان فيما سبق
+
+150
+00:11:40,570 --> 00:11:48,190
+يتم فيه استخدام نوع معين من الدراج يسمى Colombirin
+
+151
+00:11:48,190 --> 00:11:53,250
+Citrate هذا النوع من أنواع الأدوية فيما بعد تم
+
+152
+00:11:53,250 --> 00:11:58,710
+استبداله بـHuman Monopiosal Gonadotropin وخدوا
+
+153
+00:11:58,710 --> 00:12:04,250
+بالكم من كلمة monopiosal و human يعني بشريويله
+
+154
+00:12:04,250 --> 00:12:08,750
+علاقة بسن اليأس عند السيدات ثم تم استبداله بالـ
+
+155
+00:12:08,750 --> 00:12:12,810
+Urinary FSH Preparation ثم تم استبداله بال
+
+156
+00:12:12,810 --> 00:12:17,130
+Recomponent FSH يعني لو أنا عرفت التدريج تبعته،
+
+157
+00:12:17,130 --> 00:12:21,330
+هيكون في البداية عندى من الأسفل إلى الأعلى بناء
+
+158
+00:12:21,330 --> 00:12:25,590
+على التقدم هيكون فيه End Human Monobiosal
+
+159
+00:12:25,590 --> 00:12:29,600
+Gonadotropin Urinary FSH Preparationو الـ
+
+160
+00:12:29,600 --> 00:12:33,700
+Recombinant FSH Preparation إذا ماهي
+
+161
+00:12:33,700 --> 00:12:37,420
+الجونادوتروبين؟ الجونادوتروبين هي الهرمونات المهمة
+
+162
+00:12:37,420 --> 00:12:41,340
+التي تفرز من الـ anterior lobopatary gland و تأثير
+
+163
+00:12:41,340 --> 00:12:46,300
+على الـ specific cell in the ovary هذه الهرمونات
+
+164
+00:12:46,300 --> 00:12:51,300
+أفضل مثال عليها الـ FSH أو هي عبارة عن الـ FSH و
+
+165
+00:12:51,300 --> 00:12:56,950
+LH الـ human monopiosal gonadotropinمتم استخدامه
+
+166
+00:12:56,950 --> 00:13:04,630
+في البداية عام 1960 وهو عبارة عن drug يستخدم من
+
+167
+00:13:04,630 --> 00:13:09,590
+أجل تحفيز المبيض The initial preparations were
+
+168
+00:13:09,590 --> 00:13:15,530
+very impure with mainly contaminated protein with
+
+169
+00:13:15,530 --> 00:13:22,030
+less than 5% of protein being bioactive بمعنى آخر
+
+170
+00:13:22,030 --> 00:13:26,460
+أن هذاالدراج اللي سميته human monobiosal
+
+171
+00:13:26,460 --> 00:13:31,100
+gonadotropin والذي استخدم في بدايات 1960 من أجل
+
+172
+00:13:31,100 --> 00:13:37,900
+تحفيز المبيان أول ما تم إنشائه كان باحتواء على
+
+173
+00:13:37,900 --> 00:13:42,060
+كمية كبيرة جدا من الشوائب فهو not pure drug
+
+174
+00:13:42,060 --> 00:13:45,740
+بالإضافة إلى أنه في بعض ال contaminant البروتين
+
+175
+00:13:45,740 --> 00:13:49,280
+اللي مفروض ما تكون موجودة فالمفروض لمن بدأ يعمل
+
+176
+00:13:49,280 --> 00:13:53,800
+stimulation للسيدة للovering خاص بسيدة معينةلازم
+
+177
+00:13:53,800 --> 00:13:58,820
+اعطيها pure drug يعني pure هرمون مافي other
+
+178
+00:13:58,820 --> 00:14:03,280
+compound ممكن تأثر سلبا على هذا ال structure
+
+179
+00:14:03,280 --> 00:14:12,000
+الموجود في جسد السيدة مع ذلك وبتتالي الاختبارات
+
+180
+00:14:12,000 --> 00:14:16,120
+على الهرمونات المستخلصة والمستخدمة والمصنعة في عام
+
+181
+00:14:16,120 --> 00:14:23,060
+1980 تم تحسين وتطوير نوع من أنواع ال drug عملنوع
+
+182
+00:14:23,060 --> 00:14:26,060
+من أنواع الـ Improvement للـ Action و الـ
+
+183
+00:14:26,060 --> 00:14:29,720
+Structure و الـ Composition الخاصة بالـ
+
+184
+00:14:29,720 --> 00:14:35,820
+Gonadotropin تحت مصطلح مهم جدا هو الـ Urinary FSH
+
+185
+00:14:35,820 --> 00:14:40,560
+و فكرته ببساطة أن في عند السيدات اللي بتصل لمرحلة
+
+186
+00:14:40,560 --> 00:14:47,120
+الـ Monopiose هيصير كمية releasing للـ FSH و LH في
+
+187
+00:14:47,120 --> 00:14:50,190
+الـ urine بكمية كبيرة جدافكانوا ياخدوا هذا ال
+
+188
+00:14:50,190 --> 00:14:54,330
+urine ويعملوله عملية extraction او عملية خلينا
+
+189
+00:14:54,330 --> 00:14:58,850
+نقول extraction لل FSH و extraction لل LH الموجودة
+
+190
+00:14:58,850 --> 00:15:01,830
+في كميات المهولة من ال urine الخاص بالسيدات اللي
+
+191
+00:15:01,830 --> 00:15:06,270
+وصلوا للمونوبيوز و بيعملوا بعد كده عملية تنقية إذا
+
+192
+00:15:06,270 --> 00:15:11,310
+سيدات بيجمعوا منهم ال urine بس سيدة وصلت إلى سن
+
+193
+00:15:11,310 --> 00:15:15,970
+المونوبيوز جمعوا ال urine حلجوا كمية كبيرة جدا من
+
+194
+00:15:15,970 --> 00:15:20,410
+ال FSH و LH يفرص في عينة ال urineعملوا extraction
+
+195
+00:15:20,410 --> 00:15:23,610
+للـ FSH والـ LH بعدين عملوا عملية ال purification
+
+196
+00:15:23,610 --> 00:15:28,030
+باستخدام ال monoclonal antibody أو ما يُعرف باسم
+
+197
+00:15:28,030 --> 00:15:32,810
+ال affinity chromatography ثم تطور هذا الأمر فأصبح
+
+198
+00:15:32,810 --> 00:15:37,230
+لدينا قدرة على استخدام ال DNA technology أو
+
+199
+00:15:37,230 --> 00:15:40,930
+biotechnology تحت مصطلح recombinant DNA وأكيد
+
+200
+00:15:40,930 --> 00:15:44,330
+عارفين إيش عن ال recombinant DNA ببساطة جدا ال
+
+201
+00:15:44,330 --> 00:15:48,650
+recombinant DNA هو أنا بجيب fragmentمن الـ DNA للـ
+
+202
+00:15:48,650 --> 00:15:53,010
+target protein أو target هرمون و بعمله عملية
+
+203
+00:15:53,010 --> 00:15:56,470
+ligation مع vector like بلزميد و البلزميد هذا
+
+204
+00:15:56,470 --> 00:15:59,450
+بعملها insertion داخل الـ E.coli for example و
+
+205
+00:15:59,450 --> 00:16:02,790
+بدفع ال E.coli إنها تتطور و تنمو و تتضاعف بكميات
+
+206
+00:16:02,790 --> 00:16:06,590
+كبيرة جدا مما يسمح لها بعمل replication و
+
+207
+00:16:06,590 --> 00:16:09,630
+transcription و translation للمادة اللي ورا فيها
+
+208
+00:16:09,630 --> 00:16:14,610
+plus ال inserted DNA فبالتالي ال protein هينتج
+
+209
+00:16:14,610 --> 00:16:19,160
+هعمله عملية collectionExtraction Purification
+
+210
+00:16:19,160 --> 00:16:26,360
+سميته Recomponent FSH وأول ما تم استخدام نوع معين
+
+211
+00:16:26,360 --> 00:16:31,540
+من أنواع الـ Ovary سموها Chinese Hemisphere Ovary
+
+212
+00:16:31,540 --> 00:16:37,860
+Cell Line CHO Chinese Hemisphere Ovary Cell Line
+
+213
+00:16:37,860 --> 00:16:43,300
+وذلك لأنها تنتج كمية كبيرة جدا من البروتينالروتين
+
+214
+00:16:43,300 --> 00:16:47,540
+الموجود في جسم الإنسان post modification حتى بعد
+
+215
+00:16:47,540 --> 00:16:50,920
+ال post modification لأن احنا عارفين ان معظم
+
+216
+00:16:50,920 --> 00:16:54,420
+الهرمونات Alpha subunit و Beta subunit ال Alpha
+
+217
+00:16:54,420 --> 00:16:58,220
+subunit متشابهة في الجميع لل Beta subunit مختلفة
+
+218
+00:16:58,220 --> 00:17:03,020
+فوجدوا ان ال chinese hamster ovarian cell line
+
+219
+00:17:03,020 --> 00:17:06,680
+تستطيه ان تنتج Beta subunit من ال gonadotropin
+
+220
+00:17:06,680 --> 00:17:11,260
+هرميون يشبه بشكل كبير جدا جدا جدا ل human
+
+221
+00:17:11,260 --> 00:17:16,480
+gonadotropinفبالتالي أستطيع أن أجبرها و أسخرها لكي
+
+222
+00:17:16,480 --> 00:17:21,660
+تنتج هذا الهرمون المطلوب control أو مايعرف اسم ال
+
+223
+00:17:21,660 --> 00:17:25,640
+hamster أو ال chinese hamster cell line were
+
+224
+00:17:25,640 --> 00:17:29,860
+selected as recipient cell since they were easily
+
+225
+00:17:29,860 --> 00:17:33,420
+transfer with a foreign DNA and are capable to
+
+226
+00:17:33,420 --> 00:17:36,500
+synthesize a very large amount of complex
+
+227
+00:17:36,500 --> 00:17:40,840
+glycoprotein هي في عندي كمان صفتين جديدتين رغم
+
+228
+00:17:40,840 --> 00:17:44,590
+أنها بتفرز ما يشبهما يوجد في جسم الإنسان they
+
+229
+00:17:44,590 --> 00:17:47,250
+could be growing in the cell culture on a large
+
+230
+00:17:47,250 --> 00:17:50,790
+scale ممكن أنميها بكميات كبيرة جدا وكميات مهولة
+
+231
+00:17:50,790 --> 00:17:56,070
+اللي تخدمني على الصعيد ال industrial لو أنا فرجت
+
+232
+00:17:56,070 --> 00:18:01,210
+فرقت ببساطة جدا ما بين ال urinary FSH و ال human
+
+233
+00:18:01,210 --> 00:18:06,190
+monobiosis gonadotropin ال human monobiosis
+
+234
+00:18:06,190 --> 00:18:11,350
+gonadotropin يُرمز له H humanM-monobiosal G
+
+235
+00:18:11,350 --> 00:18:15,950
+-gonadotropin بيقول ببساطة إن نسبة ال FSH إلى ال
+
+236
+00:18:15,950 --> 00:18:21,410
+LH في ال HMG 1 إلى 1 بينما في ال urinary FSH
+
+237
+00:18:21,410 --> 00:18:26,190
+preparation كمية contained a small amount of LH
+
+238
+00:18:26,190 --> 00:18:30,910
+يعني كمية ال LH إلى كمية ال FSH متساوية في ال
+
+239
+00:18:30,910 --> 00:18:34,610
+human monobiosal gonadotropin ولكن كمية ال ALH
+
+240
+00:18:34,610 --> 00:18:39,300
+قليلة في ال urinary FSH من اسمهUranary FSH يعني
+
+241
+00:18:39,300 --> 00:18:44,820
+كمية الـ FSH عارية جدا طبعا الـ Follicles may be
+
+242
+00:18:44,820 --> 00:18:49,140
+exposed to the high level of LH وجدوا أن تعرض الـ
+
+243
+00:18:49,140 --> 00:18:53,180
+Ovary لكميات كبيرة جدا من الـ LH خلال عملية ال
+
+244
+00:18:53,180 --> 00:18:57,640
+development و قبل عملية ال ovulation يلعب دورة
+
+245
+00:18:57,640 --> 00:19:02,080
+سلبية على عملية ال ovulation بشكلها الأساسي مش
+
+246
+00:19:02,080 --> 00:19:07,550
+منطقي أعرض ال Ovary و ال Follicleلدوز عالم من
+
+247
+00:19:07,550 --> 00:19:13,010
+الالأتش جاب اليوم 13 و14 لأن إذا بتذكروا حكينا إن
+
+248
+00:19:13,010 --> 00:19:16,790
+الالأتش بيلعب دور مهم جدا في ال ovulation فالمفروض
+
+249
+00:19:16,790 --> 00:19:20,610
+بناء على ال chart ما يظهر إلا على هيئة sharp في
+
+250
+00:19:20,610 --> 00:19:26,150
+اليوم 13 و14 ظهوره قبل هذه الأيام يعني في أيام ال
+
+251
+00:19:26,150 --> 00:19:31,320
+development له تأثير سلبي فبالتالي المفروضما يكون
+
+252
+00:19:31,320 --> 00:19:36,040
+موجود فمنطقيا ان تأثير ال human monobiosal
+
+253
+00:19:36,040 --> 00:19:40,260
+gonadotropin إذا قرنته بال urinary FSH preparation
+
+254
+00:19:40,260 --> 00:19:45,500
+على ال development هيكون سيء إلى حد ما سيء إلى حد
+
+255
+00:19:45,500 --> 00:19:50,000
+ما فبالتالي high level of LH during their early
+
+256
+00:19:50,000 --> 00:19:52,520
+stage of development when stimulated with human
+
+257
+00:19:52,520 --> 00:19:55,920
+monobiosal gonadotropin to compare to the urinary
+
+258
+00:19:55,920 --> 00:20:00,880
+FSHهذا بيعمل عملية failure للـ follicle maturation
+
+259
+00:20:00,880 --> 00:20:05,160
+إلى حد ما من ال study have demonstrated that too
+
+260
+00:20:05,160 --> 00:20:08,420
+much allergy during this time هي follicular
+
+261
+00:20:08,420 --> 00:20:15,160
+development before ovulation day هيلعب دورة سلبية
+
+262
+00:20:15,160 --> 00:20:19,540
+ودورة سلبية في عملية ال maturation ولاجوا انه
+
+263
+00:20:19,540 --> 00:20:25,680
+associated with more one rules او more one point
+
+264
+00:20:25,680 --> 00:20:28,910
+for example the first oneبعمل reduction في ال rate
+
+265
+00:20:28,910 --> 00:20:31,730
+of fertilization بعمل reduction في ال pregnancy
+
+266
+00:20:31,730 --> 00:20:35,210
+rate و بعمل increase في ال spontaneous abortion
+
+267
+00:20:35,210 --> 00:20:39,050
+يعني السيدة إذا اتعرضت لل human
+
+268
+00:20:39,050 --> 00:20:43,570
+monopiosargonadotropin يعني ال ovary اتعرضت لدوز
+
+269
+00:20:43,570 --> 00:20:47,970
+عالي جدا من ال LH قبل أيام التطوير في الأشهر أيام
+
+270
+00:20:47,970 --> 00:20:52,410
+الأولى هذا وجدوا أنه بلعب دور سلبي و بأثر بشكل
+
+271
+00:20:52,410 --> 00:20:56,240
+سلبي على عملية ال oocyte maturationوالـ Follicular
+
+272
+00:20:56,240 --> 00:20:59,660
+Maturation أو Development، هذه نقطة وجدوا إنه
+
+273
+00:20:59,660 --> 00:21:02,820
+بيأثر سلبًا على ال rate of fertilization و rate of
+
+274
+00:21:02,820 --> 00:21:06,100
+pregnancy زيادة الألاتش في هذا المرحلة بيعمل
+
+275
+00:21:06,100 --> 00:21:10,920
+reduction فالعلاقة علاقة عكسية أيضًا وجدوا إنه
+
+276
+00:21:10,920 --> 00:21:15,680
+بيعمل زيادة في احتمالية حدوث ال abortion بسبب أو
+
+277
+00:21:15,680 --> 00:21:20,220
+من نوع spontaneous abortion هذا قران اتبان لل
+
+278
+00:21:20,220 --> 00:21:25,310
+human مونوبيوزر جونات أتروبيوالـ Urinary FSH طب لو
+
+279
+00:21:25,310 --> 00:21:28,390
+أنا قرنت بين الـ Recombinant FSH و الـ Human
+
+280
+00:21:28,390 --> 00:21:32,510
+Monobiosal Gonadotropin The main source of Human
+
+281
+00:21:32,510 --> 00:21:36,810
+Monobiosal Gonadotropin and FSH preparation هي الـ
+
+282
+00:21:36,810 --> 00:21:40,870
+urine زي ما حكينا بشكل أساسي أن المصدر الأساسي للـ
+
+283
+00:21:40,870 --> 00:21:44,530
+FSH في الـ Human Monobiosal Gonadotropin هو عبارة
+
+284
+00:21:44,530 --> 00:21:47,890
+عن الـ FSH استخلص من الـ urine sample الخاص
+
+285
+00:21:47,890 --> 00:21:52,500
+بالسيدات التي وصلت إلى أو اللواتي وصلنا إلىالـ
+
+286
+00:21:52,500 --> 00:21:55,780
+monobiosis الـ development الجديدة أو التكنيك
+
+287
+00:21:55,780 --> 00:21:58,280
+الجديد أو التكنولوجيا الجديدة اللي سميناها
+
+288
+00:21:58,280 --> 00:22:02,820
+recombinant يعني إيه؟ لأ ما إلها علاقة ما إلها
+
+289
+00:22:02,820 --> 00:22:06,880
+علاقة بال in vitro .. in vivo لأ أنا بصنا ال FSH
+
+290
+00:22:06,880 --> 00:22:13,020
+in vitro يشبه بشكل كبير قد تصل ل 99% و بعض الأحيان
+
+291
+00:22:13,020 --> 00:22:17,880
+إلى 100% إلى ال human FSH this preparation have an
+
+292
+00:22:17,880 --> 00:22:22,260
+extremely high purity which make them attractiveas
+
+293
+00:22:22,260 --> 00:22:27,480
+alternative to human monobiosargonadotropin and
+
+294
+00:22:27,480 --> 00:22:33,060
+urinary FSH وذلك لأن سلبياته و ال complications
+
+295
+00:22:33,060 --> 00:22:37,960
+خاصة فيه تعتبر قليلة جدا مقارنة بال complications
+
+296
+00:22:37,960 --> 00:22:42,600
+التي تنتج عن ال human monobiosargonadotropin or
+
+297
+00:22:42,600 --> 00:22:50,320
+urinary FSH دراساتوجريت في عام 2003 وجدت أنه مافي
+
+298
+00:22:50,320 --> 00:22:52,900
+significant مافي difference significant ما بين
+
+299
+00:22:52,900 --> 00:22:58,520
+استخدام ال HMG واستخدام ال recombinant FSH من حيث
+
+300
+00:22:58,520 --> 00:23:03,980
+نمو وفطور ال void من حيث معدل الحمل ومن حيث ال
+
+301
+00:23:03,980 --> 00:23:09,740
+life pairsكلام يحترم هذا في 2003 طب لو اتقدم الزمن
+
+302
+00:23:09,740 --> 00:23:18,800
+وجدوا في 2008 فيه دراسات وجدت انه في اختلاف في
+
+303
+00:23:18,800 --> 00:23:24,660
+ال life birth rate ما بين استخدام ال HMG و ال
+
+304
+00:23:24,660 --> 00:23:29,440
+recombinant FSH فوجدوا ان السيدات او الحالات اللي
+
+305
+00:23:29,440 --> 00:23:33,920
+اخدت recombinant FSH معدل الحمل عندهم اعلىمن
+
+306
+00:23:33,920 --> 00:23:37,180
+السيدات اللي أخدوا human monobiosis الجنادو تروبيه
+
+307
+00:23:37,180 --> 00:23:41,660
+و هذا المنطق جدا بسبب الأسباب اللي ذكرناها في مصدر
+
+308
+00:23:41,660 --> 00:23:48,300
+في أول شغلة مصطلح سموه جنادو تروبيين releasing
+
+309
+00:23:48,300 --> 00:23:53,340
+hormone agonist NGRARHA
+
+310
+00:23:53,340 --> 00:23:58,100
+جنادو تروبيين releasing hormone agonist وهو عبارة
+
+311
+00:23:58,100 --> 00:24:02,260
+عن نوع من أنواع ال protocols التي تستخدممن أجل عمل
+
+312
+00:24:02,260 --> 00:24:05,540
+down regulation for pituitary gland شو يعني down
+
+313
+00:24:05,540 --> 00:24:08,700
+regulation أنه بتقول للـ pituitary gland بيكفيكي
+
+314
+00:24:08,700 --> 00:24:14,780
+إفراز FSH و LH أنا هقوم بالوظيفة من حيث إعطاء
+
+315
+00:24:14,780 --> 00:24:19,780
+هرمونات خارجية وبالتالي أوقف إفراز الهرمونات
+
+316
+00:24:19,780 --> 00:24:25,180
+الطبيعية وأعطي هرمونات مصنعة من الخارج أتحكم في
+
+317
+00:24:25,180 --> 00:24:26,620
+كميتها كطبيب
+
+318
+00:24:30,380 --> 00:24:33,720
+طيب بالنسبة للـ gonadotropin releasing hormone
+
+319
+00:24:33,720 --> 00:24:37,980
+agonist قسموها إلى عدة أقسام بناء على ال duration
+
+320
+00:24:37,980 --> 00:24:42,380
+قسموها إلى long protocol يعني بتاخد عدد أيام أكتر
+
+321
+00:24:42,380 --> 00:24:47,000
+short protocol و ultra short protocol يعني في عندي
+
+322
+00:24:47,000 --> 00:24:50,480
+ultra short protocol و في عندي short protocol و في
+
+323
+00:24:50,480 --> 00:24:53,440
+عندي longer protocol حنا عارف جديش عدد أيام كل
+
+324
+00:24:53,440 --> 00:24:57,260
+protocolThe stimulation may be initiated in the
+
+325
+00:24:57,260 --> 00:25:00,520
+first day of that cycle إذا والله أنا بدأت ال
+
+326
+00:25:00,520 --> 00:25:03,060
+stimulation من أول يوم في الدورة من أول يوم
+
+327
+00:25:03,060 --> 00:25:07,120
+bleeding بسمي هذا ال protocol short protocol the
+
+328
+00:25:07,120 --> 00:25:12,920
+cycle preceding the stimulation cycle long
+
+329
+00:25:12,920 --> 00:25:17,520
+protocol بمعنى أخر بمعنى أخر أنه أنا عملت
+
+330
+00:25:17,520 --> 00:25:21,320
+stimulation في ال cycle السابقة هذا ال cycle
+
+331
+00:25:21,320 --> 00:25:25,070
+السابق يعني أنا أخدتتلت أربع خمس أيام من أيام
+
+332
+00:25:25,070 --> 00:25:28,970
+الدورة السابقة فمعناه هاخد سبع أيام من الدورة
+
+333
+00:25:28,970 --> 00:25:31,970
+السابقة و سبع أيام من الدورة الجديدة حتى أصل إلى
+
+334
+00:25:31,970 --> 00:25:34,830
+يوم الطبويد يعني أخدت أربعة عشر أيام بسميه long
+
+335
+00:25:34,830 --> 00:25:38,790
+protocol هاي الفرق بين ال long و ال short ال short
+
+336
+00:25:38,790 --> 00:25:42,950
+protocol بدأت من أول يوم الدورة عمل stimulation ال
+
+337
+00:25:42,950 --> 00:25:46,170
+long protocol بدأت من الأيام السابقة أخدت أيام
+
+338
+00:25:46,170 --> 00:25:49,830
+سابقة من الدورة السابقة أو أيام إضافية من الدورة
+
+339
+00:25:49,830 --> 00:25:55,540
+السابقة يعني كإني بدأت مثلا مثلافي اليوم رقم 20 من
+
+340
+00:25:55,540 --> 00:26:01,020
+الدورة السابقة و أخدت أخر 8 أيام و أخدت كمان 10
+
+341
+00:26:01,020 --> 00:26:03,720
+أيام من الدورة الجديدة و أخدت كأني ما أخدت 18 أيام
+
+342
+00:26:03,720 --> 00:26:06,980
+و بيسعلها طبعا هذه الأيام ال duration تعتمد على
+
+343
+00:26:06,980 --> 00:26:12,180
+عمر السيدة طبيعة المبيض مستوى هرموني القامعش
+
+344
+00:26:12,180 --> 00:26:17,720
+سنتحدث عن هذا مستقبلا ان شاء اللهseveral years
+
+345
+00:26:17,720 --> 00:26:23,200
+later following a several studies have been shown
+
+346
+00:26:23,200 --> 00:26:27,660
+that a long protocol gave the best result in the
+
+347
+00:26:27,660 --> 00:26:30,540
+term of pregnancy rate يعني بناء على الدراسات
+
+348
+00:26:30,540 --> 00:26:34,720
+الجديدة اللتي يتم استحداثها مقارنة ما بين ال
+
+349
+00:26:34,720 --> 00:26:38,820
+different protocol وجدوا ان معدل ال pregnancy rate
+
+350
+00:26:38,820 --> 00:26:43,600
+بيكون أفضل إذا استخدمنا ال long protocol بمنطق جيد
+
+351
+00:26:44,030 --> 00:26:46,770
+في الـ long protocol أنا ما بخضع و ما بجبر
+
+352
+00:26:46,770 --> 00:26:50,990
+البويضات أن تتطور بسرعة و ما بعطيها دوز عالي لأ
+
+353
+00:26:50,990 --> 00:26:54,810
+أنا بعطي دوز معقول خلال فترة زمنية طويلة يعني كإني
+
+354
+00:26:54,810 --> 00:26:58,790
+بخل المبيض يشتغل بوضعه الطبيعي ولكن تحت تأثير
+
+355
+00:26:58,790 --> 00:27:02,030
+الهرمونات اللي أنا بعطيها مش الهرمونات الطبيعية
+
+356
+00:27:02,030 --> 00:27:06,290
+عشان كده ممكن يكون عندي ال pregnancy rate أفضل عند
+
+357
+00:27:06,290 --> 00:27:12,090
+استخدام ال long protocolفي مادة بيسموها
+
+358
+00:27:12,090 --> 00:27:16,170
+gonadotropin-releasing hormone analogues شو يعني
+
+359
+00:27:16,170 --> 00:27:20,210
+analogues؟ ال analogues ببساطة هي عبارة عن نوع من
+
+360
+00:27:20,210 --> 00:27:24,890
+أنواع المواد المصنعة مشبه مادة طبيعية أصلية موجودة
+
+361
+00:27:24,890 --> 00:27:28,670
+في جسم الإنسان فسموها gonadotropin-releasing
+
+362
+00:27:28,670 --> 00:27:32,190
+hormone analogues هي عبارة عن short peptide من
+
+363
+00:27:32,190 --> 00:27:35,750
+gonadotropin-releasing hormone يعني هي عبارة عن
+
+364
+00:27:35,750 --> 00:27:39,290
+هرمون اسمه gonadotropin-releasing hormone ولكن
+
+365
+00:27:39,290 --> 00:27:44,860
+short peptidethat caused profound inhibition of
+
+366
+00:27:44,860 --> 00:27:48,400
+estrogen and androgen synthase وجدوا أن
+
+367
+00:27:48,400 --> 00:27:52,360
+الـAnalogues هذه، اللي هي عبارة عن short peptide
+
+368
+00:27:52,360 --> 00:27:55,600
+من الـGonadotropin releasing hormone تلعب دورة
+
+369
+00:27:55,600 --> 00:28:00,340
+مهمة جدا في تثبيت الاستروجين والتثبيت الاندروجين
+
+370
+00:28:01,980 --> 00:28:05,220
+Gynadotropin-releasing hormone analogues were
+
+371
+00:28:05,220 --> 00:28:09,280
+created by a series of modification in
+
+372
+00:28:09,280 --> 00:28:12,260
+Gynadotropin-releasing hormone molecule that led
+
+373
+00:28:12,260 --> 00:28:16,960
+to a viable of a new agonist or antagonist يعني
+
+374
+00:28:16,960 --> 00:28:19,740
+أنا جبت الـGynadotropin-releasing hormone عملت
+
+375
+00:28:19,740 --> 00:28:23,220
+عليه modification، كوللي مادة جديدة اسمها
+
+376
+00:28:23,220 --> 00:28:26,660
+Gynadotropin-releasing hormone analogues وجود هذه
+
+377
+00:28:26,660 --> 00:28:30,400
+المادة الجديدة أدت إلى وجود two protocol عظيمين
+
+378
+00:28:30,620 --> 00:28:33,440
+البروتوكول الأول اسمه agonist البروتوكول التاني
+
+379
+00:28:33,440 --> 00:28:41,240
+اسمه antagonist agonist يعني محافظة مناهض يعني
+
+380
+00:28:41,240 --> 00:28:47,280
+بيعمل ضد بمعنى أخر ال agonist بيعمل ببساطة جدا
+
+381
+00:28:47,280 --> 00:28:52,600
+enhancing for gonadotropin production كأنه بيجبر
+
+382
+00:28:52,600 --> 00:28:56,650
+ال anterior lobe أو بطيوتة رجلانعلى إنتاج كمية
+
+383
+00:28:56,650 --> 00:29:01,390
+كبيرة جدا من الـ gonadotropin بين جثين FSH وH ما
+
+384
+00:29:01,390 --> 00:29:08,370
+إستمرار إعطاء هذا الهرمون الخارجي كدا الخلية أو
+
+385
+00:29:08,370 --> 00:29:11,790
+الغدة بتقول و الله طالما فيه هرمون يأتي من الخارج
+
+386
+00:29:11,790 --> 00:29:17,150
+أنا مافي داعي أفرز فتتوقف الغدة عن الإفراز فيبقى
+
+387
+00:29:17,150 --> 00:29:21,170
+الجسم فقط يستجيب إلى كمية الـ gonadotropin التي
+
+388
+00:29:21,170 --> 00:29:25,770
+تأتي من الخارج والتي تتمثلفي الـLH والـFSH يعني
+
+389
+00:29:25,770 --> 00:29:28,970
+فكرته أنه في البداية بيحفظ الـAnterior Lobe
+
+390
+00:29:28,970 --> 00:29:32,590
+وPatentary Glan لإفراز الـGonadotropin بعد فترة مع
+
+391
+00:29:32,590 --> 00:29:35,350
+استمرار ال injection هتيجي في الـAnterior Lobe
+
+392
+00:29:35,350 --> 00:29:38,290
+وPatentary Glan ليش تجيد نفسها طالما فيه هرمون
+
+393
+00:29:38,290 --> 00:29:42,410
+جايس بييجي بيصير reduction في ال level of FSH LH
+
+394
+00:29:42,410 --> 00:29:46,210
+المفروض من الـAnterior Lobe وPatentary Glan ويتم
+
+395
+00:29:46,210 --> 00:29:50,590
+استعادة استعادة عنهم من الـGonadotropin releasing
+
+396
+00:29:50,590 --> 00:29:55,920
+hormone الذي يأتي من الخارجأول وهذا المصطلح اللي
+
+397
+00:29:55,920 --> 00:30:02,160
+سموه Gunadotropin agonist agonist يعني يحفظ ثم
+
+398
+00:30:02,160 --> 00:30:06,720
+يثبت وهي اللي شفناها حفظ الانتريو اللوب و بطيت
+
+399
+00:30:06,720 --> 00:30:11,740
+رجلها وبعدين ثبتها traditionally a tutoring down
+
+400
+00:30:11,740 --> 00:30:15,060
+regulation has been the most common protocol
+
+401
+00:30:15,060 --> 00:30:19,560
+utilized by IGC or IVF يعني كل ال protocolات اللي
+
+402
+00:30:19,560 --> 00:30:23,180
+لها علاقة بال stimulation وظيفتها الأساسية أنها
+
+403
+00:30:23,180 --> 00:30:28,170
+تقومبإيقاف الـ anterior loop وبتيوتر الجلد من
+
+404
+00:30:28,170 --> 00:30:31,750
+إفراز الـ FSH والـ H يعني كذا بتعمل ال blocking خد
+
+405
+00:30:31,750 --> 00:30:38,270
+بالكوا ال blocking مؤقت طبعا من خلال إعطاء هرمون
+
+406
+00:30:38,270 --> 00:30:41,910
+مصنع في الخارج نعطيه subcutaneous ال
+
+407
+00:30:41,910 --> 00:30:44,650
+administration of gonadotropin releasing hormone
+
+408
+00:30:44,650 --> 00:30:48,010
+agonist will be initiated the cause of releasing
+
+409
+00:30:48,010 --> 00:30:51,430
+FSH الـ H from the anterior loop هذا الكلام حكيناه
+
+410
+00:30:51,430 --> 00:30:57,060
+في ال slideالفقرة الأخيرة بعد أكثر من يوم بعد
+
+411
+00:30:57,060 --> 00:31:01,200
+several days الإعطاء المستمر بيعمل inhibition و
+
+412
+00:31:01,200 --> 00:31:04,060
+dropping في مستوى الافاساتش والقلاتش المفروض من
+
+413
+00:31:04,060 --> 00:31:06,780
+هذه ال loop أو من هذه ال gland دي اسمه anterior
+
+414
+00:31:06,780 --> 00:31:10,460
+and pituitary gland نسبة إلى وجود كمية كبيرة جدا
+
+415
+00:31:10,460 --> 00:31:14,240
+في الدم فمفيش داعة تفرز طالما في كمية كافية في
+
+416
+00:31:14,240 --> 00:31:18,520
+الدم عالية في الدم أنا ك loop اسمي anterior loop و
+
+417
+00:31:18,520 --> 00:31:22,730
+pituitary gland ما بفرز ال hormone طالما موجودةSo
+
+418
+00:31:22,730 --> 00:31:26,890
+dropping in the circulating concentration of FSH
+
+419
+00:31:26,890 --> 00:31:33,010
+and LH and to prevent LH wave or surge من خلال
+
+420
+00:31:33,010 --> 00:31:37,770
+مصطلح بيسمي desensitization أي receptor
+
+421
+00:31:37,770 --> 00:31:41,960
+desensitization يعني الفكرة ببساطةإنه أنا كطبيب
+
+422
+00:31:41,960 --> 00:31:45,340
+باعطي الـ gonadotropin-releasing hormone agonist
+
+423
+00:31:45,340 --> 00:31:51,480
+عدة أيام بحفظ الخلية أو الغدة الاسمها anterior
+
+424
+00:31:51,480 --> 00:31:55,540
+lobe وبتوتر جلاد لإفراز ال FSH والالاتش باستمرار
+
+425
+00:31:55,540 --> 00:32:00,120
+ال injection الغدة بتقول المستوى عالي أنا ما بد
+
+426
+00:32:00,120 --> 00:32:04,120
+أفرز فتتوقف على إفراز ال normal FSH والالاتش ال
+
+427
+00:32:04,120 --> 00:32:08,870
+human ال inside ال indigenousمع استمرار الإعطاء
+
+428
+00:32:08,870 --> 00:32:11,350
+بيصير ال dropping في ال level للأفقس أتش والقلقش
+
+429
+00:32:11,350 --> 00:32:14,770
+ال dropping في ال level للأفقس أتش والقلقش يؤدي
+
+430
+00:32:14,770 --> 00:32:20,290
+إلى منع تكوين القلقش search or قلقش with تحت مصطلح
+
+431
+00:32:20,290 --> 00:32:25,510
+بنسمي desensitization or receptor desensitization
+
+432
+00:32:25,510 --> 00:32:29,110
+so what's the meaning of desensitization what's
+
+433
+00:32:29,110 --> 00:32:31,170
+the meaning of receptor desensitization
+
+434
+00:32:31,810 --> 00:32:35,450
+desensitization of this phenomenon occurs when
+
+435
+00:32:35,450 --> 00:32:39,450
+receptor decreases its response to agonist at high
+
+436
+00:32:39,450 --> 00:32:44,190
+concentration يعني أنا ك response موجود على سطح ال
+
+437
+00:32:44,190 --> 00:32:48,070
+ovary أو خلايا معينة في ال ovary باستقبل ال FSH
+
+438
+00:32:48,070 --> 00:32:53,750
+هيصير استقبالي لل FSH و رضي على ال FSH من خلال ال
+
+439
+00:32:53,750 --> 00:33:00,030
+response قليل جدا هذه بنسميها desensitization it's
+
+440
+00:33:00,030 --> 00:33:06,250
+a process through whichوهذا يحدث من خلال إعطاء جرع
+
+441
+00:33:06,250 --> 00:33:09,750
+متتالية من الـ human gonadotropin-releasing
+
+442
+00:33:09,750 --> 00:33:13,710
+hormone agonist خلال عملية induction الحدث
+
+443
+00:33:13,710 --> 00:33:17,010
+Inducing Stimulation Stimulation بنسميها induction
+
+444
+00:33:17,010 --> 00:33:22,730
+كمان هذا المصطلح بسميه desensitization يعني
+
+445
+00:33:22,730 --> 00:33:28,650
+reduction in the response of receptor receptor for
+
+446
+00:33:28,650 --> 00:33:31,970
+example gonadotropin-releasing hormone agonist are
+
+447
+00:33:31,970 --> 00:33:37,400
+typeof medication that suppress ovulation by
+
+448
+00:33:37,400 --> 00:33:39,560
+stopping the production of estrogen and
+
+449
+00:33:39,560 --> 00:33:42,620
+progesterone الـ gonadotropin releasing hormone
+
+450
+00:33:42,620 --> 00:33:47,660
+agonist they had ال advantage تبعته انه عنده high
+
+451
+00:33:47,660 --> 00:33:51,560
+affinity for gonadotropin releasing hormone
+
+452
+00:33:51,560 --> 00:33:56,140
+receptor compared to native يعني انا لو قرنت ال
+
+453
+00:33:56,140 --> 00:34:02,710
+receptor لو قرنت ال receptor قابليتها للارتباطما
+
+454
+00:34:02,710 --> 00:34:05,010
+الـ agonist جناد تربين releasing hormone و لا
+
+455
+00:34:05,010 --> 00:34:08,150
+الناتيف هتلاقي اللي جناد تربين releasing hormone
+
+456
+00:34:08,150 --> 00:34:12,030
+إله قابلية للارتباط مع الـ receptor أكتر من
+
+457
+00:34:12,030 --> 00:34:15,490
+الناتيف عشان كده إله أفضلية they have greater
+
+458
+00:34:15,490 --> 00:34:19,290
+resistance to enzyme breakdown فطالما بقاوم
+
+459
+00:34:19,290 --> 00:34:22,850
+التكسير بفعل الإنزيمات المحللة إذاً هيبقى لفترة
+
+460
+00:34:22,850 --> 00:34:27,450
+زمنية طويلة جدا إذا فترة بقاءه أكتر من فترة بقاء
+
+461
+00:34:27,450 --> 00:34:30,450
+الناتيف جناد تربين releasing hormonethey have a
+
+462
+00:34:30,450 --> 00:34:34,930
+prolonged life half-life شو يعني طالما فترة بقاءه
+
+463
+00:34:34,930 --> 00:34:39,690
+أطول و طالما بيقاوم إذا فترة بقاءه أطول يعني ال
+
+464
+00:34:39,690 --> 00:34:42,630
+half-life تبعته أطول من النتيجة هذه تعتبر
+
+465
+00:34:42,630 --> 00:34:46,970
+advantage خاصة بال gonadotropin releasing hormone
+
+466
+00:34:46,970 --> 00:34:52,090
+بشكل عام ال gonadotropin releasing hormone agonist
+
+467
+00:34:52,090 --> 00:34:59,220
+يجب أن تُعطى يجب أن تُعطى لمدة 10 إلى 15 يومbefore
+
+468
+00:34:59,220 --> 00:35:02,100
+down regulation يعني قبل ما يصير ال down
+
+469
+00:35:02,100 --> 00:35:06,240
+regulation السيدة بتكون ماخدة dose من الجناد
+
+470
+00:35:06,240 --> 00:35:09,040
+التروبيين releasing hormone agonist من 10 ل 15
+
+471
+00:35:09,040 --> 00:35:16,720
+اشهر يوم علشان يصير في عيندي سرعة في استجابة ال
+
+472
+00:35:16,720 --> 00:35:20,400
+anterior loop لبطيوتر الجلد من أجل إخفاض مستوى ال
+
+473
+00:35:20,400 --> 00:35:25,140
+FSH والLH يعني سرعة في ال dropping الخاصة بال FSH
+
+474
+00:35:25,140 --> 00:35:29,510
+والLH نتيجةأو الخاصة بعمل ما يُعرف اسم
+
+475
+00:35:29,510 --> 00:35:33,110
+Downregulation of antilipopapotatory gland لازم
+
+476
+00:35:33,110 --> 00:35:36,430
+أبدأ عملية ال injection بالجناداتروبيين releasing
+
+477
+00:35:36,430 --> 00:35:40,390
+hormone في مرحلة ال middle utl phase أي ما يُعرف
+
+478
+00:35:40,390 --> 00:35:45,810
+في اليوم ال 21 من الدورة السابقة إذا أنا في عندي
+
+479
+00:35:45,810 --> 00:35:50,890
+احتمالين و التالت جاي في الطريقة الاحتمال الأول إن
+
+480
+00:35:50,890 --> 00:35:55,570
+السيدة لازم يصيرها injection و inductionبالـ
+
+481
+00:35:55,570 --> 00:35:58,830
+gonadotropin-releasing hormone agonist لمدة من 10
+
+482
+00:35:58,830 --> 00:36:02,510
+إلى 15 يوم جابل الـ down regulation علشان يصير
+
+483
+00:36:02,510 --> 00:36:06,950
+عندي down regulation سريع ببدأ في اليوم 21 من
+
+484
+00:36:06,950 --> 00:36:11,510
+الدورة السابقة ببدأ في اليوم 21 من الدورة السابقة
+
+485
+00:36:11,510 --> 00:36:15,650
+it can also be started in the early follicular
+
+486
+00:36:15,650 --> 00:36:21,600
+phase في اليوم السادس أو اليوم التلاتعاش أيضابعد
+
+487
+00:36:21,600 --> 00:36:26,340
+انتجار
+
+488
+00:36:26,340 --> 00:36:33,840
+الانترول للبطيوتر الانتجار
+
+489
+00:36:33,840 --> 00:36:34,320
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+490
+00:36:34,320 --> 00:36:36,960
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+491
+00:36:36,960 --> 00:36:37,020
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+492
+00:36:37,020 --> 00:36:37,240
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+493
+00:36:37,240 --> 00:36:41,560
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+494
+00:36:41,560 --> 00:36:50,400
+الانتجار الانتجار الانتجار الانتجار الانتجار الالـ
+
+495
+00:36:50,400 --> 00:36:54,820
+gonadotropin releasing hormone agonist كمية الإبرة
+
+496
+00:36:54,820 --> 00:36:59,100
+اللي باعطيها حتى الوصول إلى مرحلة ال ovulation
+
+497
+00:36:59,100 --> 00:37:06,720
+باعطي FSH علشان يعمل نضوج للبويضة استعدادا للإبادة
+
+498
+00:37:06,720 --> 00:37:11,640
+استعدادا لل ovulation طبعا ال dose of FSH required
+
+499
+00:37:11,640 --> 00:37:14,820
+may be different from one person to another person
+
+500
+00:37:14,820 --> 00:37:19,320
+يعني من 150 إلى 450 international unit per day
+
+501
+00:37:19,720 --> 00:37:24,500
+فبالتالي ال FSH هو المسئول عن عملية .. المسئول عن
+
+502
+00:37:24,500 --> 00:37:29,680
+عملية ال maturation of oocyte ال maturation of
+
+503
+00:37:29,680 --> 00:37:34,520
+oocyte what is the side effect of gonadotropin
+
+504
+00:37:34,520 --> 00:37:37,320
+releasing hormone agonist؟ هل هو إله side effect؟
+
+505
+00:37:37,320 --> 00:37:41,260
+أكيد إله side effect لإن أنا بعطي السيدة hormone
+
+506
+00:37:41,260 --> 00:37:44,900
+بعطيها hormone exogenous hormone فبالتالي هيكون
+
+507
+00:37:44,900 --> 00:37:49,480
+عندها side effect منها hot flush انه بقت من الحمّة
+
+508
+00:37:50,630 --> 00:37:53,690
+في عندها dryness في الفاجينة، في عندها headache،
+
+509
+00:37:53,690 --> 00:37:58,310
+fatigue، في عندها sweating في مرحلة الليل، في
+
+510
+00:37:58,310 --> 00:38:01,570
+عندها مشاكل في ال mood، ال mood غير متزن، أعصابية،
+
+511
+00:38:01,570 --> 00:38:06,390
+tension، قلقة، بتكون، في عندها decrease في ال bone
+
+512
+00:38:06,390 --> 00:38:11,270
+mineral density عندها كثافة الإظام لحد ما بتكون
+
+513
+00:38:11,270 --> 00:38:15,810
+قليلة أو تميل إلى عدم وجود mineral فيها، هذا
+
+514
+00:38:15,810 --> 00:38:18,810
+المقصود فيها طبعا الولادة الروبيين اللي لازم هرمون
+
+515
+00:38:18,810 --> 00:38:23,100
+agonistهذا كل اللي حكينا فيه عشر إلى خمس عشر يوم
+
+516
+00:38:23,100 --> 00:38:25,280
+وممكن أبدأ في اليوم الواحد وعشرين من الدورة
+
+517
+00:38:25,280 --> 00:38:28,420
+السابقة أو اليوم السادس من الدورة الحالية كله
+
+518
+00:38:28,420 --> 00:38:31,500
+علاقة بالـ long protocol تعالوا شوفوا ال short
+
+519
+00:38:31,500 --> 00:38:37,180
+protocol the continuous for a duration of two week
+
+520
+00:38:37,180 --> 00:38:41,800
+required patient to take a drug to stimulate the
+
+521
+00:38:41,800 --> 00:38:47,120
+ovaries for just five to nine days before a
+
+522
+00:38:47,120 --> 00:38:53,490
+collection rather than five4 to 5 days in long
+
+523
+00:38:53,490 --> 00:38:57,190
+protocol خدوا بالك و بيقول هنا في الـ gonadotropin
+
+524
+00:38:57,190 --> 00:39:00,270
+-releasing hormone agonist الـ long protocol بياخد
+
+525
+00:39:00,270 --> 00:39:04,490
+خمس أسابيع ال short protocol بياخد أسبوعين فقط
+
+526
+00:39:04,490 --> 00:39:09,450
+لغيره شوفت الفرق من خمس أسابيع لأسبوعين في ال long
+
+527
+00:39:09,450 --> 00:39:15,460
+protocol خمس أسابيعخمس أسابيع يوم يوم هتاخد الزوجة
+
+528
+00:39:15,460 --> 00:39:20,020
+أو السيدة induction إبر حتى وصول إلى مرحلة التفجير
+
+529
+00:39:20,020 --> 00:39:24,820
+والمقصود بالتفجير يعني ال ovulation هذا في ال long
+
+530
+00:39:24,820 --> 00:39:27,780
+في ال short protocol و notropine releasing hormone
+
+531
+00:39:27,780 --> 00:39:33,640
+agonist أسبوعين أسبوعين بتشمل ال down regulation و
+
+532
+00:39:33,640 --> 00:39:39,120
+بتشمل ال ovulation أيضافترة زمنية قوية هنا صورة
+
+533
+00:39:39,120 --> 00:39:43,920
+بتوضح الكلام اللي احنا حكينا من حيث عملية ال
+
+534
+00:39:43,920 --> 00:39:48,360
+duration لو انا عندي هذه اليوم 21 من الدورة
+
+535
+00:39:48,360 --> 00:39:52,760
+السابقة ال past cycle ال past menstrual cycle
+
+536
+00:39:52,760 --> 00:39:59,640
+الدورة الحالية 1 لحد دي اليوم 11 وهو يوم التفجير
+
+537
+00:39:59,640 --> 00:40:05,080
+اعتبره ال long protocol بدأ من يوم ال long
+
+538
+00:40:05,080 --> 00:40:11,230
+protocol بدأ منيوم 21 من الدورة السابقة فاخد عندي
+
+539
+00:40:11,230 --> 00:40:17,110
+21 و22 و23 و24 و25 و26 و27 و28 تمام أيام من الدورة
+
+540
+00:40:17,110 --> 00:40:21,550
+السابقة وكمان أخد عشر أيام من الدورة الحالية يعني
+
+541
+00:40:21,550 --> 00:40:27,030
+ما يقارب 18 يوم يعني تقريبا تلات أسابيع هذا بيسموه
+
+542
+00:40:27,030 --> 00:40:31,930
+long protocol ال short protocol بدأ فقط لغير من
+
+543
+00:40:31,930 --> 00:40:38,810
+اليوم مثلا التالت من الدورة الحاليةلحد دي عشر أيام
+
+544
+00:40:38,810 --> 00:40:44,390
+يعني تقريبا أسبوع إلا شوية ال ultra short ما بياخد
+
+545
+00:40:44,390 --> 00:40:48,310
+فترة زمنية طويلة جدا في ال stimulation ما بياخد
+
+546
+00:40:48,310 --> 00:40:51,970
+فترة زمنية طويلة جدا في ال stimulation هذه الفرق
+
+547
+00:40:51,970 --> 00:40:56,370
+بين ال long و ال short و ال ultra short ال started
+
+548
+00:40:56,370 --> 00:41:01,010
+point وين هل ال 21 من الدورة السابقة و لا اليوم
+
+549
+00:41:01,010 --> 00:41:07,480
+الأول من الدورة السابقة و لا اليومالسادس من الدورة
+
+550
+00:41:07,480 --> 00:41:12,520
+الحالية هذه اللي احنا بنحكي عنها ايش الفرق ما بين
+
+551
+00:41:12,520 --> 00:41:17,020
+ال long و ال short protocol خلينا نشوف ال short
+
+552
+00:41:17,020 --> 00:41:21,280
+protocol شو هو بناء على الفيديو وبعدين ننتقل ال
+
+553
+00:41:21,280 --> 00:41:26,980
+long protocol كمقارنة بسيطةفي الأيام الأولى من
+
+554
+00:41:26,980 --> 00:41:30,500
+المدرسة، تم التحقق من مدرسة الاندومتريام من مصفحة
+
+555
+00:41:30,500 --> 00:41:34,100
+الهوتران والتعامل مع موجودة من السيستات في
+
+556
+00:41:34,100 --> 00:41:38,120
+الـRacin
+
+557
+00:41:38,120 --> 00:41:44,620
+إذا
+
+558
+00:41:44,620 --> 00:41:48,500
+كانت كل شيء عادي، يتم تحقيق الـGnRH-Analog Agonist
+
+559
+00:41:49,720 --> 00:41:54,820
+1 أو 2 أيام لاحقاً تبدأ استخدام الهورمون FSH في
+
+560
+00:41:54,820 --> 00:42:01,200
+اليوم اليوم اليوم يومي
+
+561
+00:42:01,200 --> 00:42:02,860
+يومي يومي يومي يومي يومي يومي
+
+562
+00:42:06,690 --> 00:42:10,030
+في نهاية أقل من 4 إلى 6 أيام من التدخل، يتم تجاربه
+
+563
+00:42:10,030 --> 00:42:13,690
+مرة أخرى لتحقق رقمه ومعمومته من الفوليكولات
+
+564
+00:42:13,690 --> 00:42:18,130
+ومعمومته من الاندومتريا كل 2 أو 3 أيام، يتم تجاربه
+
+565
+00:42:18,130 --> 00:42:21,050
+مرة أخرى لتحقيق الـ Ultrasound عندما تكون أقل من 3
+
+566
+00:42:21,050 --> 00:42:26,350
+فوليكولات أكبر إلى أقل من 18 ميليمتر، يتم تحريكه
+
+567
+00:42:26,350 --> 00:42:28,770
+بالهورمون HCG
+
+568
+00:42:32,660 --> 00:42:35,500
+Oocyte recovery is undertaken 36 hours later.
+
+569
+00:42:35,960 --> 00:42:38,640
+Following the procedure, daily administration of
+
+570
+00:42:38,640 --> 00:42:41,720
+the hormone progesterone is given vaginally. Two
+
+571
+00:42:41,720 --> 00:42:44,560
+to five days after oocyte recovery, the embryos
+
+572
+00:42:44,560 --> 00:42:48,020
+are transferred. Two weeks later, a pregnancy test
+
+573
+00:42:48,020 --> 00:42:52,580
+is performed طبعا هنا بتحكي عن شغلة، شايفين هنا في
+
+574
+00:42:52,580 --> 00:42:55,060
+عيني، سماها gonadotropin-releasing hormone
+
+575
+00:42:55,060 --> 00:42:59,680
+Analogues بعدين أعطى ال FH اللي بتعمل stimulation
+
+576
+00:42:59,680 --> 00:43:04,400
+و inductionولمّا نوصلت الفولك الـ 18 ميلي متر و هي
+
+577
+00:43:04,400 --> 00:43:07,980
+عبارة عن ال .. ال .. ال diameter المسموح بعملية
+
+578
+00:43:07,980 --> 00:43:12,980
+الإبادة أعطى ما يُعرف الـ RHCG وهو عبارة عن human
+
+579
+00:43:12,980 --> 00:43:17,220
+chronic gonadotropin ولكن recombinant وعمله يشبه
+
+580
+00:43:17,220 --> 00:43:21,780
+عمل الـ LH وهو عبارة عن ال ovulation بعد كده أعطى
+
+581
+00:43:21,780 --> 00:43:25,560
+لبروجسترون بعد عملية ال embryo transfer من أجل
+
+582
+00:43:25,560 --> 00:43:28,820
+تثبيت عملية الحمل إن وجدت
+
+583
+00:43:37,790 --> 00:43:41,790
+هذا الـ long protocol طبعا بدأ من long protocol
+
+584
+00:43:41,790 --> 00:43:47,190
+هيبدأ من اليوم رقم 21 من الدورة السابقة وصولا إلى
+
+585
+00:43:47,190 --> 00:43:51,350
+اليوم 13 او 12 لعملية ال ovulation بعد كده ال
+
+586
+00:43:51,350 --> 00:43:58,120
+embryo transfer و خلافهالـ GnRH-Analog أغانيست يتم
+
+587
+00:43:58,120 --> 00:44:01,820
+استخدامه بشكل نسوي أو بشكل أساسي من اليوم الـ 21
+
+588
+00:44:01,820 --> 00:44:02,000
+من عملية عملية عملية عملية عملية عملية الـ
+
+589
+00:44:02,000 --> 00:44:05,780
+Menstrual Cycle.بالتالي، بسبب تأثير الـ LH الأول،
+
+590
+00:44:05,780 --> 00:44:09,480
+تم إطلاق الـ Pituity للـ LH والذلك يقوم بتحرير
+
+591
+00:44:09,480 --> 00:44:09,980
+عملية عملية عملية عملية عملية العملية الـ LH بشكل
+
+592
+00:44:09,980 --> 00:44:10,400
+أساسي لتحرير عملية عملية عملية عملية العملية
+
+593
+00:44:10,400 --> 00:44:11,640
+العملية العملية العملية العملية العملية العملية
+
+594
+00:44:11,640 --> 00:44:11,980
+العملية العملية العملية العملية العملية العملية
+
+595
+00:44:11,980 --> 00:44:13,140
+العملية العملية العملية العملية العملية العملية
+
+596
+00:44:13,140 --> 00:44:17,360
+العملية العملية العملفي وقت الإستعمار، يتم إتجار
+
+597
+00:44:17,360 --> 00:44:21,760
+صورة لتحقق أضعف الـEndometrium في المخزن الدوري،
+
+598
+00:44:21,760 --> 00:44:31,080
+ويقوم بإدخال موجودة من الـCysts في الأعضاء.إذا
+
+599
+00:44:31,080 --> 00:44:36,220
+كانت كل شيء عاديًا، يتم إدخال تدخلات FSH بسرعة
+
+600
+00:44:36,220 --> 00:44:38,650
+أساسيةهذا الهورمون يساعد على اكتشاف عبارة عن عبارة
+
+601
+00:44:38,650 --> 00:44:38,990
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+602
+00:44:38,990 --> 00:44:39,650
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+603
+00:44:39,650 --> 00:44:40,950
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+604
+00:44:40,950 --> 00:44:42,770
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+605
+00:44:42,770 --> 00:44:49,290
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+606
+00:44:49,290 --> 00:44:49,910
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+607
+00:44:49,910 --> 00:44:52,990
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+608
+00:44:52,990 --> 00:44:56,370
+عبارة
+
+609
+00:44:56,370 --> 00:44:58,430
+عن عب
+
+610
+00:45:00,760 --> 00:45:04,840
+كل 2 أو 3 أيام يتم تجريب جرس جديد، عندما يكوّن أقل
+
+611
+00:45:04,840 --> 00:45:08,960
+من 3 فوليكولات أكتر إلى أقل من 18 ميلي مترأخيرًا،
+
+612
+00:45:08,960 --> 00:45:14,400
+تشغّل مادة الفلائكولات مع هرمون HCG، الفلائكولات
+
+613
+00:45:14,400 --> 00:45:16,960
+الموجودة داخل الفلائكولات ستبدأ في التطور التجارب
+
+614
+00:45:16,960 --> 00:45:21,860
+الأمريكية يتعامل 36 ساعات لاحقًا، وبالتالي، يتم
+
+615
+00:45:21,860 --> 00:45:24,300
+إعادة الهرمون البروجيسترون يتم إعادة الهرمون
+
+616
+00:45:24,300 --> 00:45:27,720
+البروجيسترون بشكل عقلي، و2 إلى 5 أيام بعد التعامل
+
+617
+00:45:27,720 --> 00:45:29,460
+مع الهرمون الأمريكي، يتم إعادة التعامل مع الهرمون
+
+618
+00:45:29,460 --> 00:45:31,020
+البروجيسترون بشكل عقلي، و2 أيام لاحقًا، يتم إعادة
+
+619
+00:45:31,020 --> 00:45:34,730
+التعامل مع الهرمون البروجيسترون بشكل عقليفي كل
+
+620
+00:45:34,730 --> 00:45:37,310
+المرحلة من البداية حتى النهاية من مرحلة ال
+
+621
+00:45:37,310 --> 00:45:41,970
+induction حتى مرحلة ال beta CG analysis أنا بحكي
+
+622
+00:45:41,970 --> 00:45:45,030
+على ال long protocol تحت مصطلح gonadotropin
+
+623
+00:45:45,030 --> 00:45:48,690
+-releasing hormone analogues agonist أعطاها في
+
+624
+00:45:48,690 --> 00:45:52,290
+اليوم ال 21 من الدورة السابقة من أجل تحفيز ال
+
+625
+00:45:52,290 --> 00:45:54,870
+antiloid loop للبتيوتر gland لإنتاج الأفسادش
+
+626
+00:45:54,870 --> 00:45:57,770
+والألاتش بعد كده عملها dropping أو down or
+
+627
+00:45:57,770 --> 00:46:02,340
+shutdown أو down regulation فبطلت تفرزبعد كده عمل
+
+628
+00:46:02,340 --> 00:46:06,900
+عملية scanning لل ovary شاف ال endomaterium أو
+
+629
+00:46:06,900 --> 00:46:11,100
+بطانة الرحم نمت بشكل .. في استجابة ولا لأ؟ إذا لجأ
+
+630
+00:46:11,100 --> 00:46:13,600
+في استجابة هيبدأ يعطيها ال recomponent of a such
+
+631
+00:46:13,600 --> 00:46:19,280
+حتى اليوم ال 12 كل تلت أيام أو كل يومين بصور بشوف
+
+632
+00:46:19,280 --> 00:46:25,290
+وضع المبيضكيف هو؟ هل استجاب لهرمون علشان يظبط
+
+633
+00:46:25,290 --> 00:46:28,110
+الدوز؟ ممكن في بعض الأحيان نلاقي الاستجابة سريعة
+
+634
+00:46:28,110 --> 00:46:31,750
+فبيقلل الدوز الاستجابة بطيقة فبيزود الدوز الطبيب
+
+635
+00:46:31,750 --> 00:46:35,030
+هذا من خلال حاجة بنسميها الـ E2 level و الـ
+
+636
+00:46:35,030 --> 00:46:39,430
+Estrogen يعني و تصوير الرحم مع تصوير المبيض و
+
+637
+00:46:39,430 --> 00:46:43,050
+الفوليكل إذا الفوليكل عدد من الفوليكل أقل شيء
+
+638
+00:46:43,050 --> 00:46:46,550
+تلاتة فوليكل وصلوا إلى الـ Diameter المطلوب على 18
+
+639
+00:46:46,550 --> 00:46:50,990
+Millimeter يعني معناه فيه mature oocyteهيعطيها
+
+640
+00:46:50,990 --> 00:46:54,570
+للزوجة ما يُعرف باسم أو للسيدة ما يُعرف باسم الـ
+
+641
+00:46:54,570 --> 00:46:59,850
+Recombinant HCG الذي يعمل عملية الـ ovulation بعد
+
+642
+00:46:59,850 --> 00:47:03,750
+كده بيصير pancture أنه بيعمل aspiration للـ oocyte
+
+643
+00:47:03,750 --> 00:47:07,430
+بعدين بيعملها تلقيح بعد يومين تلاتة بيعمل embryo
+
+644
+00:47:07,430 --> 00:47:11,170
+transfer و بعد أسبوعين بيعمل pregnancy test علشان
+
+645
+00:47:11,170 --> 00:47:14,490
+نشوف ال beta HCG قداشي ال level تبعها ولكن بعد ما
+
+646
+00:47:14,490 --> 00:47:18,230
+يعمل embryo transfer لازم يعطي البروجيسترون علشان
+
+647
+00:47:18,230 --> 00:47:22,490
+يزيدمن تثبيت والـ implantation rate اللي احنا
+
+648
+00:47:22,490 --> 00:47:26,730
+بنسميها حبوب التثبيت او اغار التثبيت هي عبارة عن
+
+649
+00:47:26,730 --> 00:47:32,250
+هرمون لبروجسترون هذه فكرة الـ long protocol و
+
+650
+00:47:32,250 --> 00:47:35,610
+short protocol المتعلق بالـ gonadotropin releasing
+
+651
+00:47:35,610 --> 00:47:40,030
+hormone agonist so what is the advantage of short
+
+652
+00:47:40,030 --> 00:47:43,650
+protocol؟ ال advantage of short protocol ان انا ما
+
+653
+00:47:43,650 --> 00:47:48,070
+بجهد افضل ال advantage of short protocol أول شغلة
+
+654
+00:47:48,290 --> 00:47:51,050
+إن أنا بيصير عندي reduction في ال chance of a
+
+655
+00:47:51,050 --> 00:47:55,430
+premature and low birth weight baby بيصير عندي
+
+656
+00:47:55,430 --> 00:47:58,490
+reduction في ال risk of ovarian hyper stimulation
+
+657
+00:47:58,490 --> 00:48:03,590
+syndrome بيصير أكثر تركيزا على البويضات الناضجة
+
+658
+00:48:03,590 --> 00:48:08,170
+لوحدها بشكل طبيعي ولكن تحتاج إلى تدقيم قليل لأن في
+
+659
+00:48:08,170 --> 00:48:11,310
+بويضات بتكون ناضج طبيعي ولكن تحتاج إلى dose بسيطة
+
+660
+00:48:11,310 --> 00:48:16,030
+علشان تنضج وتنمو فهذه بتكون ال quality تبعتها جيدة
+
+661
+00:48:16,030 --> 00:48:19,900
+جدا، بتكون matureوhigh equality it is more
+
+662
+00:48:19,900 --> 00:48:24,860
+inexpensive because we used low dose of medication
+
+663
+00:48:24,860 --> 00:48:27,980
+reducing the cost of treatment يعني فيه علاقة بال
+
+664
+00:48:27,980 --> 00:48:31,700
+equality of mature oocyte في علاقة بانقاس معدل
+
+665
+00:48:31,700 --> 00:48:37,120
+حدوث ال pre mature baby في علاقة بانقاس معدل حدوث
+
+666
+00:48:37,120 --> 00:48:40,520
+ال ovarian hyperstimulation syndrome بالاضافة إلى
+
+667
+00:48:40,520 --> 00:48:45,780
+أن تكلفته قليلة إلى حد ما سوف نكتفي بهذا القدر في
+
+668
+00:48:45,780 --> 00:48:50,230
+محاضرة اليومعلى أمل أن نلتقي في محاضرات قادمة ان
+
+669
+00:48:50,230 --> 00:48:50,770
+شاء الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/UpgBJG4XVfA_raw.json b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/UpgBJG4XVfA_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..b044c93a5489cc5e0e31c34d3720724f5ffdfb1a
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/UpgBJG4XVfA_raw.json
@@ -0,0 +1 @@
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"seek": 20937, "start": 189.99, "end": 209.37, "text": "Exogenous أو Endogenous هرمون في الغالب بيكون FSH في الغالب بيكون FSH أو ما يُعرف باسم Gonadotropin والـ Gonadotropin هما نوعين FSH و LH خلال السنوات المتعاقبة التي تتعلق بعمليات الحقن المجهري والتلقيح الصناعي", "tokens": [11149, 8799, 563, 34051, 6967, 8799, 563, 8032, 2288, 2304, 11536, 8978, 6024, 118, 6027, 3555, 4724, 1829, 30544, 479, 17308, 8978, 6024, 118, 6027, 3555, 4724, 1829, 30544, 479, 17308, 34051, 19446, 7251, 10859, 3615, 28480, 4724, 32277, 2304, 460, 266, 345, 310, 1513, 259, 4032, 6027, 39184, 47403, 345, 310, 1513, 259, 8032, 15042, 8717, 45367, 9957, 479, 17308, 4032, 441, 39, 16490, 1211, 6027, 21136, 1863, 2407, 9307, 9673, 2655, 3615, 995, 4587, 49401, 38392, 6055, 2655, 30241, 4587, 4724, 25957, 20292, 9307, 21542, 4587, 1863, 9673, 7435, 3224, 16572, 16070, 2655, 1211, 38436, 5016, 31767, 8315, 3615, 1829], "avg_logprob": -0.20464199607812086, "compression_ratio": 1.6717171717171717, "no_speech_prob": 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"probability": 0.89794921875}, {"start": 764.32, "end": 764.74, "word": " ovary", "probability": 0.94677734375}, {"start": 764.74, "end": 765.44, "word": " هذه", "probability": 0.77392578125}, {"start": 765.44, "end": 766.3, "word": " الهرمونات", "probability": 0.9434291294642857}, {"start": 766.3, "end": 767.8, "word": " أفضل", "probability": 0.94873046875}, {"start": 767.8, "end": 768.28, "word": " مثال", "probability": 0.92822265625}, {"start": 768.28, "end": 768.6, "word": " عليها", "probability": 0.960693359375}, {"start": 768.6, "end": 768.78, "word": " الـ", "probability": 0.81689453125}, {"start": 768.78, "end": 769.16, "word": " FSH", "probability": 0.8798828125}, {"start": 769.16, "end": 769.4, "word": " أو", "probability": 0.75}, {"start": 769.4, "end": 769.56, "word": " هي", "probability": 0.515625}, {"start": 769.56, "end": 769.9, "word": " عبارة", "probability": 0.9952392578125}, {"start": 769.9, "end": 770.08, "word": " عن", "probability": 0.99072265625}, {"start": 770.08, "end": 770.22, "word": " الـ", "probability": 0.837890625}, {"start": 770.22, "end": 770.68, "word": " FSH", "probability": 0.9228515625}, {"start": 770.68, "end": 771.3, "word": " و", "probability": 0.744140625}, {"start": 771.3, "end": 771.94, "word": " LH", "probability": 0.60211181640625}, {"start": 771.94, "end": 772.94, "word": " الـ", "probability": 0.5316162109375}, {"start": 772.94, "end": 773.3, "word": " human", "probability": 0.64892578125}, {"start": 773.3, "end": 774.26, "word": " monopiosal", "probability": 0.75439453125}, {"start": 774.26, "end": 775.14, "word": " gonadotropin", "probability": 0.825390625}], "temperature": 1.0}, {"id": 30, "seek": 80301, "start": 775.59, "end": 803.01, "text": "متم استخدامه في البداية عام 1960 وهو عبارة عن drug يستخدم من أجل تحفيز المبيض The initial preparations were very impure with mainly contaminated protein with less than 5% of protein being bioactive بمعنى آخر أن هذا", "tokens": [2304, 39237, 44713, 9778, 3215, 10943, 3224, 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789.59, "word": " were", "probability": 0.87841796875}, {"start": 789.59, "end": 790.63, "word": " very", "probability": 0.837890625}, {"start": 790.63, "end": 792.11, "word": " impure", "probability": 0.924072265625}, {"start": 792.11, "end": 792.93, "word": " with", "probability": 0.8251953125}, {"start": 792.93, "end": 793.45, "word": " mainly", "probability": 0.381591796875}, {"start": 793.45, "end": 794.45, "word": " contaminated", "probability": 0.68798828125}, {"start": 794.45, "end": 794.97, "word": " protein", "probability": 0.57763671875}, {"start": 794.97, "end": 795.53, "word": " with", "probability": 0.56591796875}, {"start": 795.53, "end": 795.75, "word": " less", "probability": 0.9384765625}, {"start": 795.75, "end": 796.05, "word": " than", "probability": 0.9384765625}, {"start": 796.05, "end": 796.35, "word": " 5", "probability": 0.763671875}, {"start": 796.35, "end": 796.87, "word": "%", "probability": 0.83203125}, {"start": 796.87, "end": 797.29, "word": " of", 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LH", "probability": 0.912109375}, {"start": 1131.84, "end": 1132.58, "word": " خلال", "probability": 0.9775390625}, {"start": 1132.58, "end": 1132.98, "word": " عملية", "probability": 0.9835611979166666}, {"start": 1132.98, "end": 1133.18, "word": " ال", "probability": 0.814453125}, {"start": 1133.18, "end": 1133.68, "word": " development", "probability": 0.54345703125}, {"start": 1133.68, "end": 1134.34, "word": " و", "probability": 0.970703125}, {"start": 1134.34, "end": 1134.76, "word": " قبل", "probability": 0.787353515625}, {"start": 1134.76, "end": 1135.38, "word": " عملية", "probability": 0.9884440104166666}, {"start": 1135.38, "end": 1135.56, "word": " ال", "probability": 0.9306640625}, {"start": 1135.56, "end": 1136.18, "word": " ovulation", "probability": 0.8779296875}, {"start": 1136.18, "end": 1137.22, "word": " يلعب", "probability": 0.9876708984375}, {"start": 1137.22, "end": 1137.64, "word": " دورة", "probability": 0.9000651041666666}, {"start": 1137.64, "end": 1138.38, "word": " سلبية", "probability": 0.9576822916666666}, {"start": 1138.38, "end": 1138.76, "word": " على", "probability": 0.76904296875}, {"start": 1138.76, "end": 1139.18, "word": " عملية", "probability": 0.9811197916666666}, {"start": 1139.18, "end": 1139.38, "word": " ال", "probability": 0.9658203125}, {"start": 1139.38, "end": 1139.86, "word": " ovulation", "probability": 0.9150390625}, {"start": 1139.86, "end": 1140.6, "word": " بشكلها", "probability": 0.9442138671875}, {"start": 1140.6, "end": 1141.58, "word": " الأساسي", "probability": 0.9334716796875}, {"start": 1141.58, "end": 1142.08, "word": " مش", "probability": 0.53662109375}, {"start": 1142.08, "end": 1142.78, "word": " منطقي", "probability": 0.90380859375}, {"start": 1142.78, "end": 1143.8, "word": " أعرض", "probability": 0.8629557291666666}, {"start": 1143.8, "end": 1144.0, "word": " ال", "probability": 0.94287109375}, {"start": 1144.0, "end": 1144.48, "word": " Ovary", "probability": 0.824462890625}, {"start": 1144.48, 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"text": "والـ Follicular Maturation أو Development، هذه نقطة وجدوا إنه بيأثر سلبًا على ال rate of fertilization و rate of pregnancy زيادة الألاتش في هذا المرحلة بيعمل reduction فالعلاقة علاقة عكسية أيضًا وجدوا إنه بيعمل زيادة في احتمالية حدوث ال abortion بسبب أو من نوع spontaneous abortion هذا قران اتبان لل human مونوبيوزر جونات أتروبي", "tokens": [2407, 6027, 39184, 479, 1833, 14646, 6789, 8167, 34051, 15041, 12399, 29538, 8717, 47432, 3660, 49610, 3215, 14407, 36145, 3224, 4724, 1829, 10721, 49115, 8608, 46152, 14111, 995, 15844, 2423, 3314, 295, 18512, 2144, 4032, 3314, 295, 16120, 30767, 1829, 18513, 3660, 16247, 1211, 9307, 8592, 8978, 23758, 9673, 2288, 5016, 37977, 4724, 1829, 25957, 1211, 11004, 6156, 6027, 3615, 15040, 28671, 6225, 15040, 28671, 6225, 4117, 3794, 10632, 36632, 11242, 14111, 995, 49610, 3215, 14407, 36145, 3224, 4724, 1829, 25957, 1211, 30767, 1829, 18513, 3660, 8978, 1975, 33753, 2304, 6027, 10632, 11331, 3215, 2407, 12984, 2423, 22902, 4724, 35457, 3555, 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"word": " وجدوا", "probability": 0.8561197916666666}, {"start": 1270.72, "end": 1270.92, "word": " إنه", "probability": 0.916015625}, {"start": 1270.92, "end": 1271.26, "word": " بيعمل", "probability": 0.9755859375}, {"start": 1271.26, "end": 1271.86, "word": " زيادة", "probability": 0.9898681640625}, {"start": 1271.86, "end": 1272.04, "word": " في", "probability": 0.8984375}, {"start": 1272.04, "end": 1272.76, "word": " احتمالية", "probability": 0.9572265625}, {"start": 1272.76, "end": 1273.56, "word": " حدوث", "probability": 0.967529296875}, {"start": 1273.56, "end": 1273.72, "word": " ال", "probability": 0.84912109375}, {"start": 1273.72, "end": 1274.32, "word": " abortion", "probability": 0.75244140625}, {"start": 1274.32, "end": 1275.44, "word": " بسبب", "probability": 0.9855143229166666}, {"start": 1275.44, "end": 1275.68, "word": " أو", "probability": 0.8408203125}, {"start": 1275.68, "end": 1276.1, "word": " من", "probability": 0.9970703125}, {"start": 1276.1, "end": 1276.38, 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"text": "والـ Urinary FSH طب لو أنا قرنت بين الـ Recombinant FSH و الـ Human Monobiosal Gonadotropin The main source of Human Monobiosal Gonadotropin and FSH preparation هي الـ urine زي ما حكينا بشكل أساسي أن المصدر الأساسي للـ FSH في الـ Human Monobiosal Gonadotropin هو عبارة عن الـ FSH استخلص من الـ urine sample الخاص بالسيدات التي وصلت إلى أو اللواتي وصلنا إلى", "tokens": [2407, 6027, 39184, 9533, 4066, 479, 17308, 23032, 3555, 45164, 41850, 12174, 2288, 29399, 49374, 2423, 39184, 1300, 38763, 259, 394, 479, 17308, 4032, 2423, 39184, 10294, 4713, 996, 2717, 304, 47403, 345, 310, 1513, 259, 440, 2135, 4009, 295, 10294, 4713, 996, 2717, 304, 47403, 345, 310, 1513, 259, 293, 479, 17308, 13081, 39896, 2423, 39184, 27638, 30767, 1829, 19446, 11331, 4117, 1829, 8315, 4724, 8592, 28820, 5551, 3794, 32277, 1829, 14739, 9673, 9381, 3215, 2288, 16247, 3794, 32277, 1829, 24976, 39184, 479, 17308, 8978, 2423, 39184, 10294, 4713, 996, 2717, 304, 47403, 345, 310, 1513, 259, 31439, 6225, 3555, 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ال human FSH this preparation have an extremely high purity which make them attractive", "tokens": [6027, 39184, 1108, 996, 48783, 2423, 39184, 3250, 25724, 16254, 41891, 34051, 16712, 19452, 1829, 4117, 25724, 16254, 3215, 34051, 16712, 19452, 12610, 29245, 25528, 25724, 16254, 41891, 13672, 1829, 8608, 2304, 1829, 8315, 11296, 850, 3548, 259, 394, 37495, 22653, 11933, 1829, 3224, 22807, 5296, 10721, 19446, 11933, 1211, 11296, 11203, 995, 28671, 19446, 11933, 1211, 11296, 11203, 995, 28671, 20666, 294, 9467, 340, 4386, 294, 30689, 5296, 10721, 41850, 4724, 9381, 8315, 2423, 479, 17308, 294, 9467, 340, 7251, 8592, 3555, 3224, 4724, 8592, 28820, 9122, 3555, 13546, 12174, 3215, 6055, 36520, 5296, 11803, 4, 4032, 45030, 11242, 16247, 5016, 1829, 7649, 30731, 2319, 4, 30731, 2423, 1952, 479, 17308, 341, 13081, 362, 364, 4664, 1090, 34382, 597, 652, 552, 12609], "avg_logprob": -0.2423135134721956, "compression_ratio": 1.6140939597315436, "no_speech_prob": 2.980232238769531e-07, "words": 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مقارنة", "probability": 0.96064453125}, {"start": 1356.22, "end": 1356.44, "word": " بال", "probability": 0.93505859375}, {"start": 1356.44, "end": 1357.96, "word": " complications", "probability": 0.3544921875}, {"start": 1357.96, "end": 1358.8, "word": " التي", "probability": 0.83935546875}, {"start": 1358.8, "end": 1359.28, "word": " تنتج", "probability": 0.97900390625}, {"start": 1359.28, "end": 1359.48, "word": " عن", "probability": 0.97021484375}, {"start": 1359.48, "end": 1359.6, "word": " ال", "probability": 0.41943359375}, {"start": 1359.6, "end": 1359.88, "word": " human", "probability": 0.74560546875}, {"start": 1359.88, "end": 1361.76, "word": " monobiosargonadotropin", "probability": 0.97119140625}, {"start": 1361.76, "end": 1362.6, "word": " or", "probability": 0.61669921875}, {"start": 1362.6, "end": 1363.28, "word": " urinary", "probability": 0.927978515625}, {"start": 1363.28, "end": 1364.46, "word": " FSH", "probability": 0.933349609375}, {"start": 1364.46, "end": 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"text": "في مادة بيسموها gonadotropin-releasing hormone analogues شو يعني analogues؟ ال analogues ببساطة هي عبارة عن نوع من أنواع المواد المصنعة مشبه مادة طبيعية أصلية موجودة في جسم الإنسان فسموها gonadotropin-releasing hormone analogues هي عبارة عن short peptide من gonadotropin-releasing hormone يعني هي عبارة عن هرمون اسمه gonadotropin-releasing hormone ولكن short peptide", "tokens": [41185, 3714, 18513, 3660, 4724, 1829, 38251, 2407, 11296, 26307, 345, 310, 1513, 259, 12, 265, 306, 3349, 24211, 16660, 1247, 13412, 2407, 37495, 22653, 16660, 1247, 22807, 2423, 16660, 1247, 4724, 3555, 3794, 41193, 3660, 39896, 6225, 3555, 9640, 3660, 18871, 8717, 45367, 9154, 14739, 14407, 3615, 9673, 14407, 3215, 9673, 9381, 1863, 27884, 37893, 3555, 3224, 3714, 18513, 3660, 23032, 21292, 3615, 10632, 5551, 36520, 10632, 3714, 29245, 23328, 3660, 8978, 10874, 38251, 33688, 1863, 3794, 7649, 6156, 38251, 2407, 11296, 26307, 345, 310, 1513, 259, 12, 265, 306, 3349, 24211, 16660, 1247, 39896, 6225, 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أنواع", "probability": 0.947265625}, {"start": 1640.73, "end": 1641.47, "word": " المواد", "probability": 0.9482421875}, {"start": 1641.47, "end": 1642.29, "word": " المصنعة", "probability": 0.9854736328125}, {"start": 1642.29, "end": 1642.95, "word": " مشبه", "probability": 0.931640625}, {"start": 1642.95, "end": 1643.39, "word": " مادة", "probability": 0.9493815104166666}, {"start": 1643.39, "end": 1643.95, "word": " طبيعية", "probability": 0.9737548828125}, {"start": 1643.95, "end": 1644.43, "word": " أصلية", "probability": 0.731201171875}, {"start": 1644.43, "end": 1644.89, "word": " موجودة", "probability": 0.987060546875}, {"start": 1644.89, "end": 1645.01, "word": " في", "probability": 0.97705078125}, {"start": 1645.01, "end": 1645.25, "word": " جسم", "probability": 0.983642578125}, {"start": 1645.25, "end": 1646.35, "word": " الإنسان", "probability": 0.9857177734375}, {"start": 1646.35, "end": 1647.05, "word": " فسموها", "probability": 0.930908203125}, {"start": 1647.05, "end": 1648.17, "word": " gonadotropin", "probability": 0.96943359375}, {"start": 1648.17, "end": 1648.67, "word": "-releasing", "probability": 0.9593505859375}, {"start": 1648.67, "end": 1649.11, "word": " hormone", "probability": 0.95556640625}, {"start": 1649.11, "end": 1649.79, "word": " analogues", "probability": 0.9677734375}, {"start": 1649.79, "end": 1650.27, "word": " هي", "probability": 0.79833984375}, {"start": 1650.27, "end": 1650.73, "word": " عبارة", "probability": 0.9981689453125}, {"start": 1650.73, "end": 1650.93, "word": " عن", "probability": 0.99658203125}, {"start": 1650.93, "end": 1651.31, "word": " short", "probability": 0.89306640625}, {"start": 1651.31, "end": 1652.01, "word": " peptide", "probability": 0.875732421875}, {"start": 1652.01, "end": 1652.19, "word": " من", "probability": 0.99462890625}, {"start": 1652.19, "end": 1653.33, "word": " gonadotropin", "probability": 0.84580078125}, {"start": 1653.33, "end": 1653.89, "word": "-releasing", "probability": 0.9415283203125}, {"start": 1653.89, "end": 1654.31, "word": " hormone", "probability": 0.9462890625}, {"start": 1654.31, "end": 1655.07, "word": " يعني", "probability": 0.9609375}, {"start": 1655.07, "end": 1655.25, "word": " هي", "probability": 0.7607421875}, {"start": 1655.25, "end": 1655.57, "word": " عبارة", "probability": 0.998046875}, {"start": 1655.57, "end": 1655.75, "word": " عن", "probability": 0.99658203125}, {"start": 1655.75, "end": 1656.31, "word": " هرمون", "probability": 0.9501953125}, {"start": 1656.31, "end": 1656.89, "word": " اسمه", "probability": 0.95068359375}, {"start": 1656.89, "end": 1657.63, "word": " gonadotropin", "probability": 0.9162109375}, {"start": 1657.63, "end": 1657.99, "word": "-releasing", "probability": 0.96337890625}, {"start": 1657.99, "end": 1658.43, "word": " hormone", "probability": 0.92822265625}, {"start": 1658.43, "end": 1659.29, "word": " ولكن", "probability": 0.839111328125}, {"start": 1659.29, "end": 1659.69, "word": " short", "probability": 0.9130859375}, {"start": 1659.69, "end": 1660.31, "word": " peptide", "probability": 0.941650390625}], "temperature": 1.0}, {"id": 62, "seek": 168034, "start": 1660.68, "end": 1680.34, "text": "that caused profound inhibition of estrogen and androgen synthase وجدوا أن الـAnalogues هذه، اللي هي عبارة عن short peptide من الـGonadotropin releasing hormone تلعب دورة مهمة جدا في تثبيت الاستروجين والتثبيت الاندروجين", "tokens": [6780, 7008, 14382, 20406, 849, 295, 44754, 293, 293, 7747, 10657, 651, 49610, 3215, 14407, 14739, 2423, 39184, 32, 4660, 664, 1247, 29538, 12399, 13672, 1829, 39896, 6225, 3555, 9640, 3660, 18871, 2099, 41781, 482, 9154, 2423, 39184, 38, 266, 345, 310, 1513, 259, 16327, 24211, 6055, 1211, 3615, 3555, 11778, 13063, 3660, 3714, 16095, 3660, 10874, 28259, 8978, 6055, 12984, 21292, 2655, 42963, 14851, 2288, 29245, 9957, 16070, 2655, 12984, 21292, 2655, 2423, 7649, 3215, 2288, 29245, 9957], "avg_logprob": -0.2437499973922968, "compression_ratio": 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that led to a viable of a new agonist or antagonist يعني أنا جبت الـGynadotropin-releasing hormone عملت عليه modification، كوللي مادة جديدة اسمها Gynadotropin-releasing hormone analogues وجود هذه المادة الجديدة أدت إلى وجود two protocol عظيمين", "tokens": [38, 2534, 345, 310, 1513, 259, 12, 265, 306, 3349, 24211, 16660, 1247, 645, 2942, 538, 257, 2638, 295, 26747, 294, 460, 2534, 345, 310, 1513, 259, 12, 265, 306, 3349, 24211, 15582, 300, 4684, 281, 257, 22024, 295, 257, 777, 623, 266, 468, 420, 32590, 468, 37495, 22653, 41850, 10874, 3555, 2655, 2423, 39184, 38, 2534, 345, 310, 1513, 259, 12, 265, 306, 3349, 24211, 6225, 42213, 2655, 47356, 26747, 12399, 9122, 12610, 20292, 3714, 18513, 3660, 10874, 16254, 41891, 24525, 2304, 11296, 460, 2534, 345, 310, 1513, 259, 12, 265, 306, 3349, 24211, 16660, 1247, 49610, 23328, 29538, 9673, 18513, 3660, 25724, 16254, 41891, 5551, 3215, 2655, 30731, 49610, 23328, 732, 10336, 6225, 19913, 32640, 9957], "avg_logprob": -0.16176470087355926, 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Following the procedure, daily administration of the hormone progesterone is given vaginally. Two to five days after oocyte recovery, the embryos are transferred. 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" تركيزا", "probability": 0.97705078125}, {"start": 2881.85, "end": 2882.13, "word": " على", "probability": 0.82958984375}, {"start": 2882.13, "end": 2882.77, "word": " البويضات", "probability": 0.880615234375}, {"start": 2882.77, "end": 2883.59, "word": " الناضجة", "probability": 0.9285888671875}, {"start": 2883.59, "end": 2884.51, "word": " لوحدها", "probability": 0.9658203125}, {"start": 2884.51, "end": 2884.97, "word": " بشكل", "probability": 0.9934895833333334}, {"start": 2884.97, "end": 2885.49, "word": " طبيعي", "probability": 0.87158203125}, {"start": 2885.49, "end": 2885.87, "word": " ولكن", "probability": 0.892333984375}, {"start": 2885.87, "end": 2886.37, "word": " تحتاج", "probability": 0.9700520833333334}, {"start": 2886.37, "end": 2886.59, "word": " إلى", "probability": 0.84765625}, {"start": 2886.59, "end": 2887.05, "word": " تدقيم", "probability": 0.8690185546875}, {"start": 2887.05, "end": 2887.51, "word": " قليل", "probability": 0.9794921875}, {"start": 2887.51, "end": 2888.01, "word": " لأن", "probability": 0.778564453125}, {"start": 2888.01, "end": 2888.17, "word": " في", "probability": 0.89013671875}, {"start": 2888.17, "end": 2888.67, "word": " بويضات", "probability": 0.9583740234375}, {"start": 2888.67, "end": 2888.97, "word": " بتكون", "probability": 0.742919921875}, {"start": 2888.97, "end": 2889.23, "word": " ناضج", "probability": 0.9752604166666666}, {"start": 2889.23, "end": 2889.55, "word": " طبيعي", "probability": 0.906494140625}, {"start": 2889.55, "end": 2889.85, "word": " ولكن", "probability": 0.926513671875}, {"start": 2889.85, "end": 2890.31, "word": " تحتاج", "probability": 0.8922526041666666}, {"start": 2890.31, "end": 2890.49, "word": " إلى", "probability": 0.90283203125}, {"start": 2890.49, "end": 2890.71, "word": " dose", "probability": 0.392333984375}, {"start": 2890.71, "end": 2891.31, "word": " بسيطة", "probability": 0.9890625}, {"start": 2891.31, "end": 2891.97, "word": " علشان", "probability": 0.9469401041666666}, 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"end": 2926.78, "text": "وhigh equality it is more inexpensive because we used low dose of medication reducing the cost of treatment يعني فيه علاقة بال equality of mature oocyte في علاقة بانقاس معدل حدوث ال pre mature baby في علاقة بانقاس معدل حدوث ال ovarian hyperstimulation syndrome بالاضافة إلى أن تكلفته قليلة إلى حد ما سوف نكتفي بهذا القدر في محاضرة اليوم", "tokens": [2407, 21454, 14949, 309, 307, 544, 28382, 570, 321, 1143, 2295, 14041, 295, 13851, 12245, 264, 2063, 295, 5032, 37495, 22653, 8978, 3224, 11203, 995, 28671, 20666, 14949, 295, 14442, 277, 31078, 975, 8978, 11203, 995, 28671, 4724, 7649, 4587, 32277, 20449, 3215, 1211, 11331, 3215, 2407, 12984, 2423, 659, 14442, 3186, 8978, 11203, 995, 28671, 4724, 7649, 4587, 32277, 20449, 3215, 1211, 11331, 3215, 2407, 12984, 2423, 277, 8517, 952, 9848, 372, 332, 2776, 19371, 20666, 46958, 31845, 3660, 30731, 14739, 6055, 28820, 5172, 47395, 12174, 20292, 37977, 30731, 11331, 3215, 19446, 8608, 38688, 8717, 4117, 2655, 41185, 39627, 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0.9169921875}, {"start": 2903.66, "end": 2904.04, "word": " dose", "probability": 0.8271484375}, {"start": 2904.04, "end": 2904.28, "word": " of", "probability": 0.96923828125}, {"start": 2904.28, "end": 2904.86, "word": " medication", "probability": 0.9111328125}, {"start": 2904.86, "end": 2905.66, "word": " reducing", "probability": 0.80908203125}, {"start": 2905.66, "end": 2905.92, "word": " the", "probability": 0.888671875}, {"start": 2905.92, "end": 2906.16, "word": " cost", "probability": 0.90087890625}, {"start": 2906.16, "end": 2906.3, "word": " of", "probability": 0.908203125}, {"start": 2906.3, "end": 2906.66, "word": " treatment", "probability": 0.87646484375}, {"start": 2906.66, "end": 2907.24, "word": " يعني", "probability": 0.904052734375}, {"start": 2907.24, "end": 2907.46, "word": " فيه", "probability": 0.784912109375}, {"start": 2907.46, "end": 2907.86, "word": " علاقة", "probability": 0.9637044270833334}, {"start": 2907.86, "end": 2907.98, "word": " بال", "probability": 0.966796875}, {"start": 2907.98, "end": 2908.38, "word": " equality", "probability": 0.338134765625}, {"start": 2908.38, "end": 2908.62, "word": " of", "probability": 0.951171875}, {"start": 2908.62, "end": 2909.02, "word": " mature", "probability": 0.9482421875}, {"start": 2909.02, "end": 2909.64, "word": " oocyte", "probability": 0.8927408854166666}, {"start": 2909.64, "end": 2910.12, "word": " في", "probability": 0.626953125}, {"start": 2910.12, "end": 2910.56, "word": " علاقة", "probability": 0.8942057291666666}, {"start": 2910.56, "end": 2911.22, "word": " بانقاس", "probability": 0.82470703125}, {"start": 2911.22, "end": 2911.7, "word": " معدل", "probability": 0.8826497395833334}, {"start": 2911.7, "end": 2912.22, "word": " حدوث", "probability": 0.93017578125}, {"start": 2912.22, "end": 2912.74, "word": " ال", "probability": 0.9052734375}, {"start": 2912.74, "end": 2913.16, "word": " pre", "probability": 0.421630859375}, {"start": 2913.16, "end": 2914.26, "word": " mature", "probability": 0.91015625}, {"start": 2914.26, "end": 2914.7, "word": " baby", "probability": 0.90771484375}, {"start": 2914.7, "end": 2915.24, "word": " في", "probability": 0.87255859375}, {"start": 2915.24, "end": 2915.76, "word": " علاقة", "probability": 0.9622395833333334}, {"start": 2915.76, "end": 2916.36, "word": " بانقاس", "probability": 0.9090576171875}, {"start": 2916.36, "end": 2916.78, "word": " معدل", "probability": 0.9640299479166666}, {"start": 2916.78, "end": 2917.12, "word": " حدوث", "probability": 0.944091796875}, {"start": 2917.12, "end": 2917.24, "word": " ال", "probability": 0.8857421875}, {"start": 2917.24, "end": 2917.62, "word": " ovarian", "probability": 0.8527018229166666}, {"start": 2917.62, "end": 2918.42, "word": " hyperstimulation", "probability": 0.7779541015625}, {"start": 2918.42, "end": 2919.4, "word": " syndrome", "probability": 0.94091796875}, {"start": 2919.4, "end": 2920.3, "word": " بالاضافة", "probability": 0.901123046875}, {"start": 2920.3, "end": 2920.52, "word": " إلى", "probability": 0.76806640625}, {"start": 2920.52, "end": 2920.7, "word": " أن", "probability": 0.576171875}, {"start": 2920.7, "end": 2921.36, "word": " تكلفته", "probability": 0.985107421875}, {"start": 2921.36, "end": 2922.32, "word": " قليلة", "probability": 0.8914388020833334}, {"start": 2922.32, "end": 2922.62, "word": " إلى", "probability": 0.9169921875}, {"start": 2922.62, "end": 2923.18, "word": " حد", "probability": 0.991455078125}, {"start": 2923.18, "end": 2923.54, "word": " ما", "probability": 0.6474609375}, {"start": 2923.54, "end": 2924.36, "word": " سوف", "probability": 0.964111328125}, {"start": 2924.36, "end": 2924.8, "word": " نكتفي", "probability": 0.9229736328125}, {"start": 2924.8, "end": 2925.18, "word": " بهذا", "probability": 0.9658203125}, {"start": 2925.18, "end": 2925.62, "word": " القدر", "probability": 0.982421875}, {"start": 2925.62, "end": 2925.78, "word": " في", "probability": 0.97998046875}, {"start": 2925.78, "end": 2926.36, "word": " محاضرة", "probability": 0.97705078125}, {"start": 2926.36, "end": 2926.78, "word": " اليوم", "probability": 0.9765625}], "temperature": 1.0}, {"id": 110, "seek": 293077, "start": 2927.03, "end": 2930.77, "text": "على أمل أن نلتقي في محاضرات قادمة ان شاء الله", "tokens": [3615, 23942, 5551, 42213, 14739, 8717, 1211, 2655, 38436, 8978, 3714, 5016, 46958, 2288, 9307, 12174, 18513, 46007, 16472, 13412, 16606, 21984], "avg_logprob": -0.1415591045566227, "compression_ratio": 1.1095890410958904, "no_speech_prob": 0.0, "words": [{"start": 2927.03, "end": 2927.37, "word": "على", "probability": 0.93359375}, {"start": 2927.37, "end": 2927.75, "word": " أمل", "probability": 0.890380859375}, {"start": 2927.75, "end": 2927.99, "word": " أن", "probability": 0.78125}, {"start": 2927.99, "end": 2928.45, "word": " نلتقي", "probability": 0.71783447265625}, {"start": 2928.45, "end": 2928.65, "word": " في", "probability": 0.9794921875}, {"start": 2928.65, "end": 2929.33, "word": " محاضرات", "probability": 0.97578125}, {"start": 2929.33, "end": 2929.89, "word": " قادمة", "probability": 0.99365234375}, {"start": 2929.89, "end": 2930.23, "word": " ان", "probability": 0.5458984375}, {"start": 2930.23, "end": 2930.63, "word": " شاء", "probability": 0.990966796875}, {"start": 2930.63, "end": 2930.77, "word": " الله", "probability": 0.94775390625}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2932.6570625, "duration_after_vad": 2876.0822187499884}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/VNoCop9C_V4_postprocess.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/VNoCop9C_V4_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..98830f242512166d717ffac7934be8942eada165
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/VNoCop9C_V4_postprocess.srt
@@ -0,0 +1,1600 @@
+1
+00:00:00,000 --> 00:00:04,480
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:04,480 --> 00:00:09,580
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلبنا
+
+3
+00:00:09,580 --> 00:00:13,500
+الأعزاء نرجو من الله الكريم أن تكونوا بصحة جيدة
+
+4
+00:00:13,500 --> 00:00:18,480
+وبكل خيارة اليوم سوف نستكمل ما بدأنا فيه من
+
+5
+00:00:18,480 --> 00:00:22,340
+stimulation protocol what is the difference
+
+6
+00:00:22,340 --> 00:00:24,680
+between agonist and antagonist what is the
+
+7
+00:00:24,680 --> 00:00:27,800
+difference between long short ultra short protocol
+
+8
+00:00:28,380 --> 00:00:32,100
+تحدثنا في المحاضرة السابقة عن الـ Gonadotropin
+
+9
+00:00:32,100 --> 00:00:36,420
+-releasing hormone agonist protocol وقولنا أن هذا
+
+10
+00:00:36,420 --> 00:00:39,940
+ال protocol ينقسم إلى long و short و ultra short
+
+11
+00:00:39,940 --> 00:00:43,940
+بناء على ال duration time وحكينا إن هذه فكرته
+
+12
+00:00:43,940 --> 00:00:48,640
+ببساطة إن أنا بعطي السيدة gonadotropin-releasing
+
+13
+00:00:48,640 --> 00:00:52,560
+hormone analogues وظيفتها الأساسية بتعمل induction
+
+14
+00:00:52,560 --> 00:00:56,540
+و inducing و stimulationللـ anterior loop بقبطة
+
+15
+00:00:56,540 --> 00:01:01,320
+رجلان من أجل إفراز الناتيف FSH والقلاتش بعد فترة
+
+16
+00:01:01,320 --> 00:01:05,860
+زمانية باستمرار ال injection بيصير down regulation
+
+17
+00:01:05,860 --> 00:01:10,600
+للـ anterior loop مما يؤهلني إلى أطاق الركم بين
+
+18
+00:01:10,600 --> 00:01:16,660
+FSH بدوز معين ولفترة زمانية معينة تتعلق وتعتمد على
+
+19
+00:01:17,150 --> 00:01:22,110
+البطانة الرحم كيف وضعها ومدى استجابة المبيض عندما
+
+20
+00:01:22,110 --> 00:01:25,490
+تصل الفوليكل إلى أقل شيء تلاتة فوليكل وصلت إلى
+
+21
+00:01:25,490 --> 00:01:31,710
+الديامتر أكبر من أو يسوى 18 ملي ميتر ساعتها بعطي
+
+22
+00:01:31,710 --> 00:01:35,430
+ال injection اللي اسمه RHCG human corona
+
+23
+00:01:35,430 --> 00:01:39,130
+gonadotropin اللي بيعمل عمل القلش واللي بيساعد على
+
+24
+00:01:39,130 --> 00:01:43,230
+ال ovulation هذه فكرة ال gonadotropin releasing
+
+25
+00:01:43,230 --> 00:01:47,210
+hormone agonistاليوم نتكلم عن الـ Gonadotropin
+
+26
+00:01:47,210 --> 00:01:51,010
+Releasing Hormone Antagonist وكلهما يستخدم
+
+27
+00:01:51,010 --> 00:01:54,630
+Gonadotropin Releasing Hormone Analogues من أجل
+
+28
+00:01:54,630 --> 00:01:58,130
+تحفيز الـ anterior loop of pituitary gland الـ
+
+29
+00:01:58,130 --> 00:02:00,490
+Gonadotropin Releasing Hormone Antagonist
+
+30
+00:02:00,490 --> 00:02:03,350
+reversable binding to Gonadotropin Releasing
+
+31
+00:02:03,350 --> 00:02:07,210
+Hormone Receptor and prevent the releasing of FSH
+
+32
+00:02:07,210 --> 00:02:11,270
+and ALH يعني هذا الـ protocol اللي أنا بستخدمهما
+
+33
+00:02:11,270 --> 00:02:15,430
+بيحفظ الـ anterior loop و الـ pituitary gland لأ
+
+34
+00:02:15,430 --> 00:02:20,730
+بيعملها blocking بشكل مباشر وبشكل سريع من خلال
+
+35
+00:02:20,730 --> 00:02:25,430
+ارتباط مادة معينة مع الـ receptor اللي لها علاقة
+
+36
+00:02:25,430 --> 00:02:28,790
+بالـ gonadotropin-releasing hormone receptor مما
+
+37
+00:02:28,790 --> 00:02:32,810
+يؤدي إلى امتناع الـ loop الخاصة بالـ pituitary
+
+38
+00:02:32,810 --> 00:02:36,650
+gland الـ anterior loop من إفراز الـ FSH والـ LH
+
+39
+00:02:36,650 --> 00:02:41,500
+So in the antagonist protocolThere is no down
+
+40
+00:02:41,500 --> 00:02:44,900
+regulation.A gonadotropin-releasing hormone
+
+41
+00:02:44,900 --> 00:02:48,480
+antagonist bind and block the receptor of
+
+42
+00:02:48,480 --> 00:02:51,580
+gonadotropin-releasing hormone in pituitary gland
+
+43
+00:02:51,580 --> 00:02:58,800
+.This action led to immediately suppression of FSH
+
+44
+00:02:58,800 --> 00:03:03,380
+-FLH releasing يعني هنا الفرغ انه مافي اندي down
+
+45
+00:03:03,380 --> 00:03:06,720
+regulation يعني inducing بعدين reduction لأ في
+
+46
+00:03:06,720 --> 00:03:11,770
+اندي blocking بشكلمباشر من خلال إغلاق الـReceptor
+
+47
+00:03:11,770 --> 00:03:15,690
+الخاص بالـFSH والـLH.Gonadotropin-releasing
+
+48
+00:03:15,690 --> 00:03:19,730
+-hormone-antagonist have long half-life and high
+
+49
+00:03:19,730 --> 00:03:22,990
+affinity binding to the receptor of gonadotropin
+
+50
+00:03:22,990 --> 00:03:26,890
+-releasing-hormone but without activation them or
+
+51
+00:03:26,890 --> 00:03:29,630
+activating them صح إنه برتبط مع هذا الـReceptor
+
+52
+00:03:29,630 --> 00:03:34,610
+ولكن ما بحفظها بخلاف الـagonist.The gonadotropin
+
+53
+00:03:34,610 --> 00:03:37,790
+-releasing-hormone-antagonist immediately actionon
+
+54
+00:03:37,790 --> 00:03:42,290
+the prevention of LH surge and required a few
+
+55
+00:03:42,290 --> 00:03:46,990
+injections during the treatment cycle ما بحتاج إلى
+
+56
+00:03:46,990 --> 00:03:54,230
+حقن متعدد، لأ حقن بسيطة جدا، معدودة for this
+
+57
+00:03:54,230 --> 00:03:58,830
+protocol, gonadotropins are started on the cycle 2
+
+58
+00:03:58,830 --> 00:04:02,610
+in the cycle day number 2 يعني هذا ال protocol
+
+59
+00:04:02,610 --> 00:04:06,090
+بتميز أنه يبدأ في اليوم أو يمكن أن نبدأ فيه في
+
+60
+00:04:06,090 --> 00:04:10,110
+اليوم التاني من الدورةفمش محتاج ناخد من اليوم رقم
+
+61
+00:04:10,110 --> 00:04:14,490
+21 من الدورة السابقة ال advantage الخاصة فيه fewer
+
+62
+00:04:14,490 --> 00:04:19,270
+injections زي ما اتكلمنا قبل بشوية بيعمل
+
+63
+00:04:19,270 --> 00:04:24,270
+suppression ل ال FSH و ال LH بشكل سريع فبالتالي
+
+64
+00:04:24,270 --> 00:04:29,450
+بحتاج إلى injection و عدد قليل جدا بيعمل reduction
+
+65
+00:04:29,450 --> 00:04:33,390
+في فرصة حدوث الجنادو ال Oberian hyperstimulation
+
+66
+00:04:33,390 --> 00:04:38,760
+syndrome بعض الدراساتأو وجدت معلومات معينة ونتاج
+
+67
+00:04:38,760 --> 00:04:42,100
+معين على سبيل المثال وجدت أن الـ gonadotropin
+
+68
+00:04:42,100 --> 00:04:47,420
+-releasing hormone antagonist was effectiveness
+
+69
+00:04:47,420 --> 00:04:51,340
+as gonadotropin-releasing hormone analogues for
+
+70
+00:04:51,340 --> 00:04:56,420
+prevention of premature LH surge يعني وجدوا أن
+
+71
+00:04:56,420 --> 00:05:02,440
+كفائته ال effectiveness طبعته على منع ال premature
+
+72
+00:05:02,440 --> 00:05:10,650
+LH surgeأعلى من الـ agonist ايضا
+
+73
+00:05:10,650 --> 00:05:14,010
+احتمالية الحصول على ال pregnancy clinical
+
+74
+00:05:14,010 --> 00:05:18,970
+pregnancy وجدوا rate was shown to be lower than
+
+75
+00:05:18,970 --> 00:05:21,750
+gonadotropin releasing hormone antagonist group
+
+76
+00:05:21,750 --> 00:05:25,310
+وجدوا ان ال pregnancy rate عند استخدام ال
+
+77
+00:05:25,310 --> 00:05:28,950
+gonadotropin releasing hormone antagonist أقل ايضا
+
+78
+00:05:28,950 --> 00:05:32,530
+there is no difference in the life birth rateيعني
+
+79
+00:05:32,530 --> 00:05:37,250
+هذه تعتبر دراسات بعضهم قالت أن والله ال antagonist
+
+80
+00:05:37,250 --> 00:05:40,510
+أفضل من ال agonist بعضهم قال مافي اختلاف ما بينهم
+
+81
+00:05:40,510 --> 00:05:43,450
+و بعض قال لأ والله ال pregnancy rate as a clinical
+
+82
+00:05:43,450 --> 00:05:47,250
+pregnancy rate في ال antagonist أقل من ال agonist
+
+83
+00:05:47,250 --> 00:05:52,550
+فبتدالها دراسات تختلف بناء على طبيعة الدراسة في
+
+84
+00:05:52,550 --> 00:05:55,750
+ND2 protocol خاصة بال antagonist ال protocol الأول
+
+85
+00:05:55,750 --> 00:05:59,050
+اسمه single dose protocol و ال protocol التاني
+
+86
+00:05:59,050 --> 00:06:02,690
+اسمه multiply dose protocolبالـ Single dose
+
+87
+00:06:02,690 --> 00:06:06,130
+protocol أنا بعطي dose واحد بمعدل تلاتة milligram
+
+88
+00:06:06,130 --> 00:06:12,750
+في مرحلة ال late follicular stage في ال multiple
+
+89
+00:06:12,750 --> 00:06:16,470
+dose أنا بعطي أكتر من dose بشكل يومي بمعدل ربع
+
+90
+00:06:16,470 --> 00:06:19,850
+milligram من ال analogues اللي هي عبارة عن جولات
+
+91
+00:06:19,850 --> 00:06:22,850
+ربين و raising hormone analogues تبدأ في اليوم
+
+92
+00:06:22,850 --> 00:06:26,010
+الخامس أو السادس من الدورة هذا الفرق بين ال single
+
+93
+00:06:26,010 --> 00:06:31,950
+dose و multiple dose protocolصورة بتوضح الفرق بين
+
+94
+00:06:31,950 --> 00:06:34,490
+ال agonist و ال antagonist لو بدأت انا من ال
+
+95
+00:06:34,490 --> 00:06:37,490
+agonist هى ال hypothalamus هى ال pituitary gland
+
+96
+00:06:37,490 --> 00:06:40,150
+هى ال receptor الخاص بال gonadotropin releasing
+
+97
+00:06:40,150 --> 00:06:44,650
+hormone receptor انا هنا باعطي gonadotropin
+
+98
+00:06:44,650 --> 00:06:47,710
+releasing hormone analogues هترتبط بال receptor
+
+99
+00:06:47,710 --> 00:06:51,190
+فهتحفظ ال receptor الموجودة على ال anterior loop
+
+100
+00:06:51,190 --> 00:06:53,490
+فبتدفع ال anterior loop و ال pituitary gland
+
+101
+00:06:53,490 --> 00:06:58,290
+لإفراز كمية كبيرة جدا من الأفسش و الألاتشفي لحظة
+
+102
+00:06:58,290 --> 00:07:05,030
+معينة تتوقف بتبطل تفرز الـLH والـLH أنا كطبيب ببدأ
+
+103
+00:07:05,030 --> 00:07:09,230
+أعطي الـrecombinant FSH هذا ما نسميه agonist
+
+104
+00:07:09,230 --> 00:07:14,790
+الـantagonist لأ مباشرة المادة اللي تحققن تعمل
+
+105
+00:07:14,790 --> 00:07:18,290
+blocking للـreceptor الموجودة في الـpatietary
+
+106
+00:07:18,290 --> 00:07:22,490
+gland فتعمل على إيقاف الـgonadotropin releasing
+
+107
+00:07:22,490 --> 00:07:29,150
+releasing like FSH and LH فبالتاليبعطي مباشرة ال
+
+108
+00:07:29,150 --> 00:07:32,030
+recombinant همجمون من الخارج هذا الفرق بين ال
+
+109
+00:07:32,030 --> 00:07:38,150
+agonist و ال antagonist طيب بعد ما عرفنا الفرق بين
+
+110
+00:07:38,150 --> 00:07:43,230
+ال agonist و ال antagonist صورة بتوضح و بتعمل
+
+111
+00:07:43,230 --> 00:07:47,290
+summarization لكل ال information اللي احنا اتكلمنا
+
+112
+00:07:47,290 --> 00:07:51,850
+عنها سابقا فلو انا بديت لو نفرض ان عندي هي اليوم
+
+113
+00:07:51,850 --> 00:07:55,470
+الأول من الدورة و هذه الأيام السابقة من الدورة
+
+114
+00:07:55,470 --> 00:08:01,500
+السابقةفي الـ ultra short و short و long و long
+
+115
+00:08:01,500 --> 00:08:06,420
+mid-uteal protocol و agonist هذا كله .. عفوًا هذا
+
+116
+00:08:06,420 --> 00:08:09,940
+antagonist هذا كله agonist اللي فوق ال ultra short
+
+117
+00:08:09,940 --> 00:08:13,980
+لحد دي ال long هذا كله agonist في ال ultra short
+
+118
+00:08:13,980 --> 00:08:17,600
+بدأ من اليوم الأول للدورة أعطى جناد تروبين
+
+119
+00:08:17,600 --> 00:08:21,400
+releasing hormone analogues تلت أيام بعضين أعطى
+
+120
+00:08:21,400 --> 00:08:27,030
+FSH بعضين في اليوم العاشر أعطىالـ human coronary
+
+121
+00:08:27,030 --> 00:08:30,790
+gonadotropin اللي بيعمل ovulation فجدتش أخد أيام
+
+122
+00:08:30,790 --> 00:08:37,270
+تقريبا 10 أيام في ال short اختلف الموضوع أعطى
+
+123
+00:08:37,270 --> 00:08:42,430
+Analogues تلت أيام من الدورة بعدين أعطى FSH plus
+
+124
+00:08:42,430 --> 00:08:45,090
+gonadotropin releasing hormone Analogues علشان
+
+125
+00:08:45,090 --> 00:08:49,050
+يستمر في تحفيز ال anterior loop of pituitary gland
+
+126
+00:08:49,050 --> 00:08:53,150
+من أجل إنتاج ال FSH والLHلما نصل إلى الـ
+
+127
+00:08:53,150 --> 00:08:58,410
+Downregulation حيس يعطي الـ FSH Recomponent ويصل
+
+128
+00:08:58,410 --> 00:09:02,450
+لاداميتر المطلوب للفوليكل من أجل إعطاء الـ Human
+
+129
+00:09:02,450 --> 00:09:06,650
+-Corona-Gonadotropin في الـ Long Protocol المفروض
+
+130
+00:09:06,650 --> 00:09:09,990
+في الـ Long Protocol عندي نوعين Long Protocol في
+
+131
+00:09:09,990 --> 00:09:13,210
+الـ Follicular Stage و Long Protocol في الـ Middle
+
+132
+00:09:13,210 --> 00:09:17,210
+Blutial Stage Long Protocol في الـ Follicular ببدأ
+
+133
+00:09:17,210 --> 00:09:21,010
+من اليوم الأول من الدورة الحالية هيعطي Analogues
+
+134
+00:09:21,010 --> 00:09:26,800
+لمدة13 يوم او 12 يوم بعدين بمجرد ما يصير down
+
+135
+00:09:26,800 --> 00:09:31,280
+regulation هيعطي ال recomponent FSH بمجرد الفلك
+
+136
+00:09:31,280 --> 00:09:35,040
+اللي ما تصل الى 18 ميلي متر او اكبر هيعطي ال HCG
+
+137
+00:09:35,040 --> 00:09:39,420
+اللي سميتها هي human chronic gonadotropin اللي
+
+138
+00:09:39,420 --> 00:09:44,310
+بيشتغل شغل ال LH وهي ال ovulationفي الـ Long
+
+139
+00:09:44,310 --> 00:09:48,230
+Middle Luteal Protocol حيبدأ بإعطاء الجنادو تروبين
+
+140
+00:09:48,230 --> 00:09:51,790
+Releasing Hormone Analogues من آخر عشر أيام في
+
+141
+00:09:51,790 --> 00:09:58,990
+الدورة السابقة ويستمر إلى اليوم السابع
+
+142
+00:09:58,990 --> 00:10:03,710
+من الدورة الحالية تجريبا اليوم السابع أو اليوم
+
+143
+00:10:03,710 --> 00:10:07,690
+التامن، اليوم السابع بعد كده، هيستمر بإعطاء
+
+144
+00:10:07,690 --> 00:10:10,830
+الجنادو تروبين Releasing Hormone حتى يصل إلى مرحلة
+
+145
+00:10:10,830 --> 00:10:14,310
+الـ Down Regulationof anterior lobopertatory gland
+
+146
+00:10:14,310 --> 00:10:19,450
+وقتها هيعطي ال FSH من أجل إنضاج البويضات بمجرد
+
+147
+00:10:19,450 --> 00:10:23,650
+البويضة ما تنضج وتنضج بشكل كامل وتصل الفولكل
+
+148
+00:10:23,650 --> 00:10:28,330
+الأكبر من أو تسبب 18 ميلي متر هيبدأ يعطي هرمون
+
+149
+00:10:28,330 --> 00:10:32,810
+مسئول عن عملية ال ovulation هذه كلها ال protocol
+
+150
+00:10:32,810 --> 00:10:36,530
+هذه الأربع اللي حكينا عنها هي عبارة عن
+
+151
+00:10:36,530 --> 00:10:42,200
+gonadotropin releasing hormone agonistنأتي للـ
+
+152
+00:10:42,200 --> 00:10:46,080
+Antagonist الـ Antagonist ما في عندي Analogues
+
+153
+00:10:46,080 --> 00:10:49,580
+بمعنى آخر، ما في عندي Down Regulation في عندي
+
+154
+00:10:49,580 --> 00:10:55,460
+مباشرة Blocking للـ Receptor الخاصة بالـ FSH
+
+155
+00:10:55,460 --> 00:10:58,760
+والألاتش الموجودة في الـ Anterior Loop فبيعطي FSH
+
+156
+00:10:58,760 --> 00:11:03,260
+مباشرة، بعدين بيعطي FSH Recombinant المسئولة عن
+
+157
+00:11:03,260 --> 00:11:06,920
+عملية إنضاج الفوليكل لما انتصر الفوليكل للحد
+
+158
+00:11:06,920 --> 00:11:09,760
+المطلوب والدياميتر المطلوب، بيعطيها لـ Human
+
+159
+00:11:09,760 --> 00:11:13,750
+Chronic Gonadotropinهذا المقصود فيها Antagonist
+
+160
+00:11:13,750 --> 00:11:18,830
+الـ Agonist Stimulation Releasing Stopping الـ
+
+161
+00:11:18,830 --> 00:11:22,970
+Antagonist Stopping Directly Without Activation،
+
+162
+00:11:22,970 --> 00:11:28,070
+Without Stimulation هذا الفرق ما بين الاتنين طيب،
+
+163
+00:11:28,070 --> 00:11:32,990
+العملية إعطاء الجرأ هادي و إعطاء الهرمونات و إعطاء
+
+164
+00:11:32,990 --> 00:11:35,490
+الـ Analogues و إعطاء الـ F-Acetyl-Component
+
+165
+00:11:35,490 --> 00:11:38,050
+البروتين و إعطاء الـ Human Colonic Gonadotropin
+
+166
+00:11:38,050 --> 00:11:42,090
+المسئول عن الـ Ovulation هل تحدث عبثاً؟هل يجب أن
+
+167
+00:11:42,090 --> 00:11:45,370
+تخضأ إلى عملية monitoring؟ لأ يجب أن تخضأ إلى
+
+168
+00:11:45,370 --> 00:11:49,210
+عملية monitoring بشكل مستمر حتى بعض المختبرات و
+
+169
+00:11:49,210 --> 00:11:54,130
+بعض المراكز بتعمل monitoring يوم بيوم كل يوم لازم
+
+170
+00:11:54,130 --> 00:11:58,590
+الزوجة تيجي تعمل E2 level examination و تعمل
+
+171
+00:11:58,590 --> 00:12:02,190
+vaginal ultrasound examination يعني انا بحدد مستوى
+
+172
+00:12:02,190 --> 00:12:08,970
+ال E2 و باخد صورة للأوبري والرحم بشكل مستمر بعد
+
+173
+00:12:08,970 --> 00:12:13,260
+الدراسات جالتE2 level is used to determine the
+
+174
+00:12:13,260 --> 00:12:16,800
+dose of gonadotropin and if under or over
+
+175
+00:12:16,800 --> 00:12:20,720
+stimulation okay يعني جدش انا فيه عندى E2 جدش
+
+176
+00:12:20,720 --> 00:12:25,300
+المفروض يكون فيه عندى بوايضة لأن كل بوايضة بتفرز
+
+177
+00:12:25,300 --> 00:12:29,240
+كمية معينة من ال E2 لو انا حددت جدش عندى كمية ال
+
+178
+00:12:29,240 --> 00:12:34,760
+E2 وجسمت على كمية ال E2 المفرز من كل بوايضة هعرف
+
+179
+00:12:34,760 --> 00:12:40,000
+تقديرا إلى حد اللي ما جدش عندي mature oversightبعض
+
+180
+00:12:40,000 --> 00:12:45,300
+الدراسات قالت إن الـ E2 ليس له أهمية يكفي أن نعمل
+
+181
+00:12:45,300 --> 00:12:48,280
+monitoring من خلال ما يُعرف باسم الـ vaginal
+
+182
+00:12:48,280 --> 00:12:53,340
+ultrasound examination and so the E2 level is not
+
+183
+00:12:53,340 --> 00:12:56,520
+necessary is not always necessary and the response
+
+184
+00:12:56,520 --> 00:12:59,160
+to the treatment can be followed by ultrasound
+
+185
+00:12:59,160 --> 00:13:02,800
+monitoring only the goal for ovarian hyper
+
+186
+00:13:02,800 --> 00:13:07,740
+stimulation is to develop at least three mature
+
+187
+00:13:07,740 --> 00:13:14,410
+oocyteأو 3 mature follicle الديامتر أكبر من أو
+
+188
+00:13:14,410 --> 00:13:20,670
+يساوي 18 مليلتر بعضهم بيديني لأ بيكفلي 18 بدي يكون
+
+189
+00:13:20,670 --> 00:13:26,090
+الديامتر من 22 ل 24 بس كحد أخدنا 18 و يطلع لازم
+
+190
+00:13:26,090 --> 00:13:31,530
+يكون ال follicle as diameter 18 مليمتر طيب لما نصل
+
+191
+00:13:31,530 --> 00:13:36,020
+أو تصل ال follicle لديامتر المطلوباقتصى للدياميتر
+
+192
+00:13:36,020 --> 00:13:39,960
+المطلوب يكون 18 ميلي متر ال FSH و الاخرى مدعومين
+
+193
+00:13:39,960 --> 00:13:44,880
+مستمرين و الانجيكشن الوحيد من الهيومان كورونادو
+
+194
+00:13:44,880 --> 00:13:48,060
+تروبيل يجب أن يتم إعطاءه لتعامل الفوليكين و يسمح
+
+195
+00:13:48,060 --> 00:13:52,260
+له فرتاليز يعني وصلت الفوليكين لحد المطلوب و وصلت
+
+196
+00:13:52,260 --> 00:13:56,420
+للدياميتر المطلوبة خلاص بواجف اعطاء ال FSH و ال
+
+197
+00:13:56,420 --> 00:13:59,140
+medication الأخرى او ال injection الأخرى و بعطي
+
+198
+00:13:59,140 --> 00:14:04,020
+injection واحدة بهرمون اسمه HCG hormone واضيف
+
+199
+00:14:04,020 --> 00:14:07,730
+تقولناتشبه وظيفة الـLH وهي مسئولة عن الـ ovulation
+
+200
+00:14:07,730 --> 00:14:12,770
+الـ HCG لـ administration will be cause ovulation
+
+201
+00:14:12,770 --> 00:14:17,550
+so it is equal in the function like LH but this
+
+202
+00:14:17,550 --> 00:14:22,290
+does not occur until 36 to 40 hours after the
+
+203
+00:14:22,290 --> 00:14:26,750
+injection طبعا عملية ال ovulation ما بتحدث بشكل
+
+204
+00:14:26,750 --> 00:14:31,430
+مباشر لأتحدث بعد 36 إلى 40 ساعة من ال injection
+
+205
+00:14:31,430 --> 00:14:37,110
+يعني لو أنا أعطيت الزوجة ال HCG الساعة 4 العصر عيد
+
+206
+00:14:37,110 --> 00:14:41,070
+36 ساعة إلى 40 ساعة خلال الفترة هذه لازم يصير عندي
+
+207
+00:14:41,070 --> 00:14:45,970
+ovulation therefore it is standard that the HCG
+
+208
+00:14:45,970 --> 00:14:49,990
+injection is administrated 36 hours before the
+
+209
+00:14:49,990 --> 00:14:55,230
+schedule egg collected such thatthis will allow a
+
+210
+00:14:55,230 --> 00:14:58,790
+quieted maturation of the oocyte and yet there
+
+211
+00:14:58,790 --> 00:15:02,090
+would be little risk for ovulation علشان كده مهم
+
+212
+00:15:02,090 --> 00:15:05,130
+جدا انت كانسان بيشتغل في هذا المجال انك تعمل
+
+213
+00:15:05,130 --> 00:15:09,050
+schedule time table time انا لو اعطيت السيدة هذه
+
+214
+00:15:09,050 --> 00:15:15,550
+ال hcg الساعة كده الساعة الخامسة متى المفروض اجمع
+
+215
+00:15:15,550 --> 00:15:18,250
+البويضات الستة و تلاتين ساعة نهايتها متى هتكون
+
+216
+00:15:18,250 --> 00:15:21,990
+علشان اشوف هل جدوة اللي بسمح ولا لأ لأنه مش منطق
+
+217
+00:15:21,990 --> 00:15:26,370
+اخليهابعد 36 ساعة انتظر انه ممكن يصير ovulation
+
+218
+00:15:26,370 --> 00:15:29,550
+انا مابدي يصير ovulation انا بدي اصل الى لحظة ال
+
+219
+00:15:29,550 --> 00:15:32,710
+ovulation قبلها بقليل و ادخل بالنيد الوهم ال
+
+220
+00:15:32,710 --> 00:15:38,070
+aspiration هاي المقصود بالموضوع ايجينا مصطلح مهم
+
+221
+00:15:38,070 --> 00:15:42,270
+جدا كلمنا عنه باختصار شديد في البداية المحاضرة
+
+222
+00:15:42,270 --> 00:15:46,170
+السابقة وهي ovarian hyper stimulation syndrome ال
+
+223
+00:15:46,170 --> 00:15:48,770
+ovarian hyper stimulation syndrome هو عبارة عن
+
+224
+00:15:48,770 --> 00:15:53,910
+حالة ومظهريحدث عند السيدات اللى ممكن يخضعوا لل
+
+225
+00:15:53,910 --> 00:15:57,090
+injection أو ال induction أو ال stimulation
+
+226
+00:15:57,090 --> 00:16:02,670
+فبالتالي بيصير عندى مشكلة في مستوى الهرمونات
+
+227
+00:16:02,670 --> 00:16:07,390
+treatment that taking hormone as injection or a
+
+228
+00:16:07,390 --> 00:16:12,230
+drug to stimulation the ovary and increase the
+
+229
+00:16:12,230 --> 00:16:18,750
+number of oocyte it will be evaluated ovulated it
+
+230
+00:16:18,750 --> 00:16:23,890
+will be ovulatedBut there are rare cases of OHSS
+
+231
+00:16:23,890 --> 00:16:27,150
+occurring spontaneously يعني بوضع الطبيعي أن هذا
+
+232
+00:16:27,150 --> 00:16:30,910
+المرض أو هذه الحالة أو هذه ال case اللي سميتها
+
+233
+00:16:30,910 --> 00:16:34,170
+ovarian hyperstimulation syndrome ما بتحدث في شكل
+
+234
+00:16:34,170 --> 00:16:38,210
+تلقائي إلا في عدد قليل جدا لا يذكر معظم الحالات
+
+235
+00:16:38,210 --> 00:16:40,790
+اللي تم تأكيدها أنها ovarian hyperstimulation
+
+236
+00:16:40,790 --> 00:16:44,910
+syndrome بتكون لسيدات خضعوا إلى ال ovarian
+
+237
+00:16:44,910 --> 00:16:50,260
+induction أو ال ovarian stimulationطيب ال OHSS
+
+238
+00:16:50,260 --> 00:16:52,620
+happened during fertility treatment using
+
+239
+00:16:52,620 --> 00:17:00,400
+medication you take by mouth such as Clomipherine
+
+240
+00:17:00,400 --> 00:17:04,000
+يعني بعض السيدات ممكن تكون ماخدة fertility
+
+241
+00:17:04,000 --> 00:17:10,920
+treatment عن طريق ال mouth فممكن يظهر عندها زي
+
+242
+00:17:10,920 --> 00:17:14,640
+عفوا ال Clomipherine فممكن يظهر عندها ما يعرف باسم
+
+243
+00:17:14,640 --> 00:17:20,440
+ال OHSSالـ excessive dose للهرمونات التي تُعطى
+
+244
+00:17:20,440 --> 00:17:28,720
+بدون أي رقابة قد تؤدي إلى حدوث OHSS مما يصاحبه من
+
+245
+00:17:28,720 --> 00:17:34,180
+زيادة في حجم المبيض، تضخم في حجم المبيض، ظهور للـ
+
+246
+00:17:34,180 --> 00:17:37,720
+cyst حوالين المبيض، وضفق لكمية كبيرة جدا من ال
+
+247
+00:17:37,720 --> 00:17:43,600
+fluid في الـ intravascular space فبالتالي قسموا من
+
+248
+00:17:43,600 --> 00:17:48,470
+حيث ال severity إلى moderate و severeقسموا من حيث
+
+249
+00:17:48,470 --> 00:17:52,890
+بقض الحدوث إلى Early وLate قسموا من حيث الأسباب
+
+250
+00:17:52,890 --> 00:17:59,790
+إلى spontaneous وحاجة بنتسموها heterogenic وهي
+
+251
+00:17:59,790 --> 00:18:03,930
+عبارة عن حالة مرضية تحدث بالفعل تناول السيدة
+
+252
+00:18:03,930 --> 00:18:08,150
+لهرمونات عن طريق ال mouth أو عن طريق ال injection
+
+253
+00:18:08,150 --> 00:18:17,960
+ال Early OHSS تظهربعد عملية ال ovulation بعد ال
+
+254
+00:18:17,960 --> 00:18:22,700
+ovulatory dose بتلت إلى سبع أيام of the HCG where
+
+255
+00:18:22,700 --> 00:18:27,260
+as ال late من 12 إلى 17 دقيقة يعني وين اليوم اللي
+
+256
+00:18:27,260 --> 00:18:34,400
+تم اعطاء الزوج ال HCG ممكن يظهر ال OHSS إذا ظهر من
+
+257
+00:18:34,400 --> 00:18:38,500
+اتنين لتلت أيام بعد ال ovulation بيكون early إذا
+
+258
+00:18:38,500 --> 00:18:43,040
+ظهر بعد اتناشر يوم بيكون lateمشكلة أكتر لـ Ovarian
+
+259
+00:18:43,040 --> 00:18:48,540
+hyperstimulation syndrome هي أتاروجينك بسبب إعطاء
+
+260
+00:18:48,540 --> 00:18:54,100
+الجونادوتروبين الهرمون كمية قليلة جدا تحدث بفعل
+
+261
+00:18:54,100 --> 00:18:58,900
+spontaneous قد تكون بفعل الـ mutation أثرت على الـ
+
+262
+00:18:58,900 --> 00:19:02,500
+receptor المسؤول عن استقبال الـ FSH و الـLH مما
+
+263
+00:19:02,500 --> 00:19:06,580
+أدى إلى حدوث الـ Ovarian hyperstimulation syndrome
+
+264
+00:19:06,580 --> 00:19:11,590
+الذي يؤثر على الـ pregnancy بشكل عامEvarian
+
+265
+00:19:11,590 --> 00:19:14,550
+hyperstimulation syndrome, we can classify it
+
+266
+00:19:14,550 --> 00:19:17,750
+according to the severity into mild, moderate,
+
+267
+00:19:18,310 --> 00:19:23,070
+severe وفي بعض الأحيان بيسموه critical grade الـ
+
+268
+00:19:23,070 --> 00:19:27,270
+mild الـ ovary إذا أنا قسته عن طريق ال ultrasound
+
+269
+00:19:27,270 --> 00:19:31,490
+هيكون أقل من 8 cm و في الغالب بيكون عندها mild ال
+
+270
+00:19:31,490 --> 00:19:35,630
+symptoms اللي علاقة بالأبدومير المoderate إذا أنا
+
+271
+00:19:35,630 --> 00:19:39,030
+قست ال ovary من خلال ال ultrasound هيكون من 8 إلى
+
+272
+00:19:39,030 --> 00:19:47,730
+12الـ fluid حوالين الـ abdominal البريتونيوم في
+
+273
+00:19:47,730 --> 00:19:51,610
+الـ severe هيكون ال diameter بتاع ال ovary أكتر من
+
+274
+00:19:51,610 --> 00:19:57,010
+12 صنطي و هذه حالة مقلقة إلى حد ما بالنسبة ل ال
+
+275
+00:19:57,010 --> 00:19:59,890
+mild و ال moderate ال symptoms بصير عندها
+
+276
+00:19:59,890 --> 00:20:04,550
+abdominal pain السيدة بصير عندها زيادة في محيط
+
+277
+00:20:04,550 --> 00:20:09,190
+الخسر و عندها انتفاخات بصير عندها adenasia و
+
+278
+00:20:09,190 --> 00:20:12,880
+vomiting دياريابصير في عندها تصلب في منطقة الـ
+
+279
+00:20:12,880 --> 00:20:16,000
+ovary أيضًا الـ severe ovarian hyperstimulation
+
+280
+00:20:16,000 --> 00:20:19,620
+syndrome بصير في عندها rapid weight تكتسب
+
+281
+00:20:19,620 --> 00:20:25,500
+increasing in the body weight بشكل سريع جدًا بمعدل
+
+282
+00:20:25,500 --> 00:20:29,620
+1 kilogram لكل 24 ساعة بصير عندها abdominal pain
+
+283
+00:20:29,620 --> 00:20:32,520
+بصير عندها nasal vomiting very severe بصير عندها
+
+284
+00:20:32,520 --> 00:20:34,760
+decrease في ال urination بصير في عندها blood
+
+285
+00:20:34,760 --> 00:20:38,940
+clotting بصير في عندها problem in the breathing
+
+286
+00:20:38,940 --> 00:20:42,290
+short breathingبصير عندها أيضًا enlargement في
+
+287
+00:20:42,290 --> 00:20:47,890
+منطقة الـ Tide ومنطقة الـ Abdomen طب إيش العامل
+
+288
+00:20:47,890 --> 00:20:50,310
+اللي ممكن يتزيد من فرصة حدوث الـ Ovarian
+
+289
+00:20:50,310 --> 00:20:54,370
+Hyperstimulation Syndrome؟ أول عامل وأختارهم هو
+
+290
+00:20:54,370 --> 00:20:57,630
+الـ Polycystic Ovarian Syndrome الـ Polycystic
+
+291
+00:20:57,630 --> 00:21:02,030
+Ovarian Syndrome حالة مرضية بتعاني منها بعض
+
+292
+00:21:02,030 --> 00:21:06,910
+السيدات اللي لهم أصلاً history خاص بالـ Polycystic
+
+293
+00:21:06,910 --> 00:21:11,970
+Ovarian Syndromeمشكلة polycystic ovarian syndrome
+
+294
+00:21:11,970 --> 00:21:16,730
+هو بيظهر سيست في منطقة الـ ovary مما يؤدي إلى
+
+295
+00:21:16,730 --> 00:21:19,910
+خربطة في ال menstrual cycle بيبقى ال menstrual
+
+296
+00:21:19,910 --> 00:21:24,810
+cycle مش منتظمة طبعا هذا بيمنع الإنجاب أو يؤخر
+
+297
+00:21:24,810 --> 00:21:28,690
+الإنجاب ولكن لا يمنعه بشكل مطلق ممكن لو تم إزالة
+
+298
+00:21:28,690 --> 00:21:35,460
+السيست مع إلاجات ترجع السيدة تنجب بشكل طبيعيممكن
+
+299
+00:21:35,460 --> 00:21:39,880
+ال risk factor يزيد لو تم اعطاء الزوجة او السيدة
+
+300
+00:21:39,880 --> 00:21:43,780
+دوز عالي من ال human كوروناتروبين خلال ال IVF
+
+301
+00:21:43,780 --> 00:21:50,260
+cycle او اعطت large number of follicles ممكن بعضهم
+
+302
+00:21:50,260 --> 00:21:57,840
+يكون free امرها اقل من 35 ال body weight very low
+
+303
+00:21:57,840 --> 00:22:03,440
+او عندها في تاريخ الطب اصابات سابقة بال ovarian
+
+304
+00:22:03,440 --> 00:22:08,780
+hyper stimulationSo what is the complication؟
+
+305
+00:22:08,780 --> 00:22:11,760
+الكمبليكيشن لهذه الحالة المرضية أول حاجة بتسميها
+
+306
+00:22:11,760 --> 00:22:16,320
+من الكمبليكيشن وجود imbalance في ال electrolyte
+
+307
+00:22:16,320 --> 00:22:20,300
+وذلك بسبب severe fluid will be shifted out of the
+
+308
+00:22:20,300 --> 00:22:22,060
+blood vessels may be effected on the blood
+
+309
+00:22:22,060 --> 00:22:26,120
+pressure أنه بيصير في shifting كمية كبيرة جدا من
+
+310
+00:22:26,120 --> 00:22:31,000
+السواعر من الدموية إلى الفراغ ما بين الخلايافهذا
+
+311
+00:22:31,000 --> 00:22:36,020
+يجعل لدي الـ Electrolyte imbalance في عندي status
+
+312
+00:22:36,020 --> 00:22:41,620
+of thrombotic abnormality وذلك بفعل عند وجود خلل
+
+313
+00:22:41,620 --> 00:22:45,980
+في الأستروجين لأن الأستروجين بيلعب دور مهم جدا as
+
+314
+00:22:45,980 --> 00:22:51,060
+a pro-coagulant hormone one may develop
+
+315
+00:22:51,060 --> 00:22:55,460
+hemoconcentration and cause abnormal blood clot in
+
+316
+00:22:55,460 --> 00:23:01,660
+large vessels usually lower limbفي عندى مشكلة في
+
+317
+00:23:01,660 --> 00:23:07,020
+مستوى الأستروجين في السيدات اللى عندهم ovarian
+
+318
+00:23:07,020 --> 00:23:11,240
+hyperstimulation syndrome فبصير عندهم مشاكل في ال
+
+319
+00:23:11,240 --> 00:23:14,200
+coagulation cascade أو ال coagulation status أو ال
+
+320
+00:23:14,200 --> 00:23:18,640
+thrombotic status بفعل وجود خلل في الأستروجين لإن
+
+321
+00:23:18,640 --> 00:23:21,920
+الأستروجين في الأصل بيشتغل ك pro-coagulant hormone
+
+322
+00:23:21,920 --> 00:23:25,320
+فيممكن يصير عندها من أحد ال complications kidney
+
+323
+00:23:25,320 --> 00:23:32,200
+فالية مشاكل في ال ovaryالتوقعات في الـ Ovary يصير
+
+324
+00:23:32,200 --> 00:23:34,780
+في عندي rupture للسست الموجودة مما يؤدي إلى حدوث
+
+325
+00:23:34,780 --> 00:23:38,180
+ال bleeding ممكن يصير عندي مشكلة في ال breathing
+
+326
+00:23:38,180 --> 00:23:41,540
+ماتقدر تاخد نفسها بفعل كمية كبيرة جدا من ال fluid
+
+327
+00:23:41,540 --> 00:23:45,420
+اللي تسربت فتضغط على الرؤى ممكن يصير عندها
+
+328
+00:23:45,420 --> 00:23:48,880
+abortion, miscarriage ممكن يؤدي إلى ال death في
+
+329
+00:23:48,880 --> 00:23:53,300
+بعض الحالات سجلات سيدات بسبب النزيف الداخلي العصبي
+
+330
+00:23:53,300 --> 00:23:56,700
+مثلًا بسبب كمية ال fluid الموجودة على الرؤتين بفعل
+
+331
+00:23:56,700 --> 00:23:59,580
+أحد ال complicationsفي فئة ال bleeding هذه كلها
+
+332
+00:23:59,580 --> 00:24:03,320
+إذا كانت مافي monitoring مافي treatment قد تؤدي
+
+333
+00:24:03,320 --> 00:24:09,100
+إلى الوفاة فبالتالي كيف يمكن تجنب هذا القمر ال
+
+334
+00:24:09,100 --> 00:24:14,080
+prevention من خلال أول حاجة أن أعمل evaluation و
+
+335
+00:24:14,080 --> 00:24:19,520
+adjusting ل ال medication الدكتور و الطبيب المعالج
+
+336
+00:24:19,770 --> 00:24:23,790
+لازم يتأكد من كمية من الجرعة وكيفية يعطاها ويعطاها
+
+337
+00:24:23,790 --> 00:24:28,110
+بالشكل السريب الجرعة المناسبة تحدد من خلال عدد
+
+338
+00:24:28,110 --> 00:24:33,690
+الـboilers التي تؤهل للنضوج كيف هي استجابة المبيض
+
+339
+00:24:33,690 --> 00:24:38,510
+للـanalogues اللتي تُعطى أو للهرمونات اللتي تُعطى
+
+340
+00:24:38,510 --> 00:24:42,810
+أيضًا، some medications seem to reduce the risk of
+
+341
+00:24:42,810 --> 00:24:45,510
+ovarian hyperstimulation syndrome without
+
+342
+00:24:45,510 --> 00:24:49,710
+affecting the odds of pregnancyبعض الأحيان فيه
+
+343
+00:24:49,710 --> 00:24:54,850
+medication توصف تتأدي إلى خفض معدل أو risk factor
+
+344
+00:24:54,850 --> 00:24:58,030
+لهذا الحالة أو لهذا المرض ولكن ما بتأثر على ال
+
+345
+00:24:58,030 --> 00:25:01,790
+fertility و ما بتأثر على ال pregnancy ايضا بياضف
+
+346
+00:25:01,790 --> 00:25:06,610
+إلى ذلك من اهم الأمور التثبيت او الهبوط ايش يعني
+
+347
+00:25:06,610 --> 00:25:10,890
+التثبيت او الهبوط يعني انا ممكن اقلل الجرعة ببساطة
+
+348
+00:25:10,890 --> 00:25:14,870
+جدا ما اخليها ع جرعة واحدة if your estrogen for
+
+349
+00:25:14,870 --> 00:25:19,170
+example level is very high or you havea large
+
+350
+00:25:19,170 --> 00:25:21,950
+number of development follicle your doctor may
+
+351
+00:25:21,950 --> 00:25:25,630
+have you stop injectable medication and wait a few
+
+352
+00:25:25,630 --> 00:25:29,870
+days يعني والله خمس أيام بيعطيها جرعة معينة من
+
+353
+00:25:29,870 --> 00:25:35,310
+الهرمونات لجى فجأة الاستروجين عالي جدا عمل ال
+
+354
+00:25:35,310 --> 00:25:38,710
+ultrasound كمية كبيرة جدا او عدد لبأس فيه من ال
+
+355
+00:25:38,710 --> 00:25:43,650
+follicle قريب انه ينضج يصير mature مافي عندي مشكلة
+
+356
+00:25:43,650 --> 00:25:47,330
+لو وقفت عملية ال injection يوم يومين تلاتة اربع
+
+357
+00:25:47,330 --> 00:25:52,210
+حتىأؤخر عملية الـ maturation وما أخلى الزوجة أو
+
+358
+00:25:52,210 --> 00:25:54,390
+السيدة تدخل في الـ ovarian hyperstimulation
+
+359
+00:25:54,390 --> 00:25:59,310
+syndrome بعد كده أرجع أعطيها الهرمونات مرة جديدة
+
+360
+00:25:59,310 --> 00:26:02,270
+لاستكمال عملية ال ovarian أو الfurricular
+
+361
+00:26:02,270 --> 00:26:06,270
+maturation هذا ما في عندها مشكلة أنه أهبط و أخفض
+
+362
+00:26:06,270 --> 00:26:10,450
+الجرعة مافي مشكلة أيضا حاجة مهمة جدا أن نعمل
+
+363
+00:26:10,450 --> 00:26:14,370
+cancel ال cycle cancellation او canceling cycleمش
+
+364
+00:26:14,370 --> 00:26:18,190
+غلط انه انا لو كان معظم المعايير و المؤشرات
+
+365
+00:26:18,190 --> 00:26:20,870
+بتقولوا ان هذه الزوجة او هذه السيدة هتروح لل
+
+366
+00:26:20,870 --> 00:26:24,730
+ovarian hyper stimulation syndrome مش غلط ان اوجف
+
+367
+00:26:24,730 --> 00:26:28,130
+ال cycle و اعمل dropping و اعمل canceling لل cycle
+
+368
+00:26:28,130 --> 00:26:32,450
+و اريح السيدة شهر شهرين تلاتة و ارجع من أوله جديد
+
+369
+00:26:32,450 --> 00:26:42,090
+في cycle جديدة مش غلط يعني خسارة قريبة أفضل من ما
+
+370
+00:26:42,090 --> 00:26:48,720
+اكسب بعيدمهم جدا ان انا اوقف الـ cycle اوقف ال
+
+371
+00:26:48,720 --> 00:26:51,760
+stimulation اوقف ال induction في الوقت المناسب
+
+372
+00:26:51,760 --> 00:26:57,260
+holding HCG used to be the most common method used
+
+373
+00:26:57,260 --> 00:27:00,240
+to prevent ovarian hyperstimulation syndrome in
+
+374
+00:27:00,240 --> 00:27:03,480
+patients predicted to be at high risk for
+
+375
+00:27:03,480 --> 00:27:05,460
+development or to development of ovarian
+
+376
+00:27:05,460 --> 00:27:09,480
+hyperstimulation syndrome بمعنى اخر انه حكوا
+
+377
+00:27:09,870 --> 00:27:16,650
+العلماء أن أي سيدة مستوى الاستروجين بيكون أكبر من
+
+378
+00:27:16,650 --> 00:27:23,770
+أو يساوي 4000 Pg per ml هذه السيدة مؤهلة للدخول في
+
+379
+00:27:23,770 --> 00:27:27,190
+الـ Ovarian Hyper Stimulation صندوق فبالتالي قدامك
+
+380
+00:27:27,190 --> 00:27:31,110
+حال من الإتنين يا تخفض الدوز أو توقفها مؤقت أو
+
+381
+00:27:31,110 --> 00:27:36,910
+توقف عملية ال induction equal or more important
+
+382
+00:27:36,910 --> 00:27:40,700
+and criticalfor cancelling cycle than estradiol
+
+383
+00:27:40,700 --> 00:27:46,100
+level are the number of follicle اربعة تمانية
+
+384
+00:27:46,100 --> 00:27:49,820
+لعشرة ملي متر follicle that maybe have acquired
+
+385
+00:27:49,820 --> 00:27:55,740
+الاتش ريسبتور خد بجنب ال E2 جدش عندي عدد ال
+
+386
+00:27:55,740 --> 00:27:58,620
+follicle اللي وصلت ل تمانية لعشرة ملي متر يعني
+
+387
+00:27:58,620 --> 00:28:02,740
+ضايقها اربعة ملي متر و تصل ل ال mature ممكن يكون
+
+388
+00:28:02,740 --> 00:28:06,500
+عندي ما تقدر تصل ل ال mature فبالتالي هعضيها دوز
+
+389
+00:28:06,500 --> 00:28:10,910
+عاليهستمر في عضاء الدوز يعني كأني بجبر المبيض انه
+
+390
+00:28:10,910 --> 00:28:14,210
+ينضج لأكبر عدد من الـ follicle التي تحتوي على
+
+391
+00:28:14,210 --> 00:28:18,270
+البويضات الناضجة وهذا مشكلة بيقع فيها بعض الأطباء
+
+392
+00:28:18,270 --> 00:28:21,910
+انه ما بياخدوا القرار المناسب في الوقت المناسب من
+
+393
+00:28:21,910 --> 00:28:27,090
+أجل إيقاف الدورة أو انقاص الدوز أو إيقاف الدوز ولو
+
+394
+00:28:27,090 --> 00:28:31,430
+بشكل مؤقت هذه الأمور المتعلقة بالـ ovarian
+
+395
+00:28:31,430 --> 00:28:36,320
+hyperstimulation syndrome بالإضافة إلىالكمبليكيشن
+
+396
+00:28:36,320 --> 00:28:40,300
+ال risk factor وكيف ممكن نعمل presentation أو نعمل
+
+397
+00:28:40,300 --> 00:28:44,760
+avoiding لل ovarian hyperstimulation syndrome سوف
+
+398
+00:28:44,760 --> 00:28:48,360
+نتوقف عند هذا الكام من المعلومات في هذه المحاضرة
+
+399
+00:28:48,360 --> 00:28:52,340
+على أمل أن نلتقي في محاضرات قادمة ان شاء الله دوم
+
+400
+00:28:52,340 --> 00:28:53,540
+دوم في حفظ الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Vk4A33MkSlQ.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Vk4A33MkSlQ.srt
new file mode 100644
index 0000000000000000000000000000000000000000..8c596a3973551e199b94dc1e940e390c4c52533f
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Vk4A33MkSlQ.srt
@@ -0,0 +1,2747 @@
+1
+00:00:00,670 --> 00:00:04,590
+بسم الله الرحمن الرحيم والصلاة والسلام على أفضل
+
+2
+00:00:04,590 --> 00:00:09,750
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا 
+
+3
+00:00:09,750 --> 00:00:14,110
+الأعزاء أرجو من الله الكريم أن تكونوا جميعا بخير 
+
+4
+00:00:14,110 --> 00:00:19,430
+وبصحة جيدة. تكلمنا في المحاضرات السابقة عن أمور شتى
+
+5
+00:00:19,430 --> 00:00:25,430
+تتعلق بقضية التلقيح وعملية الحقن المجهري ومن أشهر 
+
+6
+00:00:25,430 --> 00:00:29,820
+هذه المواضيع التي تحدثنا عنها كيف تتكون الجَمِيْطات 
+
+7
+00:00:29,820 --> 00:00:33,980
+عند الـ male و الـ female تحت عنوان spermatogenesis
+
+8
+00:00:33,980 --> 00:00:39,460
+و oogenesis كيف تنتقل هذه الجَمِيْطات من مكان التصنيع 
+
+9
+00:00:39,460 --> 00:00:44,800
+إلى مكان التخزين ثم إلى مكان التطور والنضوج لكي 
+
+10
+00:00:44,800 --> 00:00:49,500
+يمكن أن تُستخدم ثم تحدثنا عن القالية التي يتم من 
+
+11
+00:00:49,500 --> 00:00:53,240
+خلالها تحضير الأطباق الخاصة بالحقن المجهري 
+
+12
+00:00:53,240 --> 00:00:58,200
+تحت عنوان XY dish preparation ثم تحدثنا عن عملية 
+
+13
+00:00:58,200 --> 00:01:02,620
+الحقن المجهري وكيف تتم ومن خلال عملية التحدث عن 
+
+14
+00:01:02,620 --> 00:01:05,760
+الحقن المجهري تحدثنا عن آلية التعامل مع الـ 
+
+15
+00:01:05,760 --> 00:01:09,060
+spermatozoa من خلال مصطلح سميناه sperm 
+
+16
+00:01:09,060 --> 00:01:14,240
+immobilization spermatozoa ثم تحدثنا عن الـ oocyte 
+
+17
+00:01:14,240 --> 00:01:19,040
+preparation من خلال عملية الـ denudation وهي عبارة 
+
+18
+00:01:19,040 --> 00:01:23,720
+عن التخلص من الخلايا الذائدة المحيطة بالبويضات 
+
+19
+00:01:23,720 --> 00:01:29,080
+الناضجة التي تصلح لعملية الحقن. الآن تمت عملية 
+
+20
+00:01:29,080 --> 00:01:34,320
+الحقن. سوف نتحدث عن عدة أمور مختلفة لها بالعلاقة 
+
+21
+00:01:34,320 --> 00:01:39,080
+بانقسام الخلايا الملقحة أو البويضات الملقحة وكيف 
+
+22
+00:01:39,080 --> 00:01:43,420
+تنقسم هذه البويضات وماذا تُسمى كل مرحلة من مراحل 
+
+23
+00:01:43,420 --> 00:01:48,460
+الانقسام ثم كيف تنتقل البويضة الملقحة من مكان 
+
+24
+00:01:48,460 --> 00:01:52,220
+التلقيح الطبيعي وهو عبارة عن الـ Fallopian tube 
+
+25
+00:01:52,220 --> 00:01:58,040
+حتى حدوث عملية implantation في بطانة الرحمة. هذا ما 
+
+26
+00:01:58,040 --> 00:02:02,440
+سوف نتحدث عنه في هذا الشيء من هذه المحاضرة ثم 
+
+27
+00:02:02,440 --> 00:02:07,280
+ننتقل إلى موضوع جديد وهو كيف نحدد بعض الأمراض 
+
+28
+00:02:07,280 --> 00:02:11,580
+الوراثية المتعلقة بالأجنة من خلال ما يُعرف اسم 
+
+29
+00:02:11,580 --> 00:02:18,850
+Empyreobiosis أو polar body biopsy هذا ما سوف نتحدث 
+
+30
+00:02:18,850 --> 00:02:23,670
+عنه في الـ Chapter رقم 6 After fertilization، بعد 
+
+31
+00:02:23,670 --> 00:02:27,090
+عملية الـ fertilization وهو إدخال single sperm في 
+
+32
+00:02:27,090 --> 00:02:31,470
+mature oocyte تبدأ عملية اندماج النواة الذكرية مع 
+
+33
+00:02:31,470 --> 00:02:35,530
+النواة الأنثوية، مما يؤدي إلى تكوين خلية جديدة تُسمى 
+
+34
+00:02:35,530 --> 00:02:41,450
+الزيجوت فالزيجوت هي عبارة عن أول ناتج طبيعي لعملية 
+
+35
+00:02:41,450 --> 00:02:45,840
+الحقن المجهري. إلى العملية تكوين الزيجوت بيحدث 
+
+36
+00:02:45,840 --> 00:02:50,360
+shifting لـ metabolic process و الـ event اللي ممكن 
+
+37
+00:02:50,360 --> 00:02:55,080
+تحدث في الخلية والبوايضة الملقحة مما يؤدي إلى 
+
+38
+00:02:55,080 --> 00:03:00,060
+دخولها في عدة انقسامات للحصول على الـ embryo الذي 
+
+39
+00:03:00,060 --> 00:03:04,620
+سوف يحدث له عملية implantation في بطانة الرحم 
+
+40
+00:03:04,620 --> 00:03:10,290
+ليكوّن a new baby خلال هذه الفترة وخلال هذه العملية 
+
+41
+00:03:10,290 --> 00:03:14,730
+من لحظة التلقيح وتكون الـ Zygote حتى لحظة الـ 
+
+42
+00:03:14,730 --> 00:03:18,410
+implantation يبقى الجنين أو قبل لحظة الـ 
+
+43
+00:03:18,410 --> 00:03:22,270
+implantation بشيء بسيط يبقى الجنين والخلايا 
+
+44
+00:03:22,270 --> 00:03:26,190
+الجنينية محاطة بغلاف واحد وهو عبارة عن الـ 
+
+45
+00:03:26,190 --> 00:03:31,410
+Zona pellucida و لا يتحطم هذا الغلاف يعني ما بيصير 
+
+46
+00:03:31,410 --> 00:03:35,210
+the structure أو breakdown for Zona pellucida حتى 
+
+47
+00:03:35,210 --> 00:03:39,630
+لحظة الـ implantation بمجرد أن يصل الجنين لعدد معين 
+
+48
+00:03:39,630 --> 00:03:44,310
+من القسمات والخلايا ويصل للمكان المعد له لكي يحدث 
+
+49
+00:03:44,310 --> 00:03:47,270
+له عملية انغراض في بطانة الرحم تبدأ الـ 
+
+50
+00:03:47,270 --> 00:03:50,670
+Zona pellucida في التهتك وتبدأ الـ Zona pellucida 
+
+51
+00:03:50,670 --> 00:03:55,910
+في التكسر والتحطم لكي تسمح بوجود منفذ لهذا الجنين 
+
+52
+00:03:55,910 --> 00:04:00,930
+لحدوث اتصال مباشر ما بينه وما بين بطانة الرحم 
+
+53
+00:04:00,930 --> 00:04:04,170
+الموجودة في المنطقة التي يحدث لها عملية الـ 
+
+54
+00:04:04,170 --> 00:04:10,040
+implantation إلى حد ما حوالي 6 أيام بعد ذلك 
+
+55
+00:04:10,040 --> 00:04:15,380
+الانبريو شد ذونا باليوسيدا واتشت اليوتران لين يعني 
+
+56
+00:04:15,380 --> 00:04:20,060
+بعد ست أيام من عملية الحقل أو بعد ست أيام بالضبط 
+
+57
+00:04:20,060 --> 00:04:26,860
+يبدأ الانبريو بالخروج من الذونا باليوسيدا الاتفاق 
+
+58
+00:04:26,860 --> 00:04:31,140
+بين البلاسنتل والماترة التي أدت لإنقاذ الوحوسيت 
+
+59
+00:04:31,140 --> 00:04:35,400
+لتخزين كمية يوكساك that needed during development
+
+60
+00:04:35,400 --> 00:04:39,440
+therefore the eggs of mammalian are very small هذه 
+
+61
+00:04:39,440 --> 00:04:44,920
+الفقرة بتوضع سؤال مهم جدا لو أنا قرنت البويضة 
+
+62
+00:04:44,920 --> 00:04:49,300
+الخاصة بالفديات زي الـ human مع البويضة الخاصة بالـ 
+
+63
+00:04:49,300 --> 00:04:54,180
+animal بالطيور مثلا في بعض الحيوانات بتبيض على 
+
+64
+00:04:54,180 --> 00:05:00,260
+سبيل المثال فيه. فبالتالي لو أنا قرنت حجم البويضة 
+
+65
+00:05:00,260 --> 00:05:04,270
+مع حجم البويضة الأخرى هلاجي حجم البويضة الخاصة 
+
+66
+00:05:04,270 --> 00:05:08,190
+بليه human صغيرة جدا مقارنة مع حجم البويضة الخاصة 
+
+67
+00:05:08,190 --> 00:05:14,490
+ببعض أنواع من الطيور أو بعض أنواع من الحيوانات 
+
+68
+00:05:14,490 --> 00:05:19,150
+التي الطبيب فالسبب في هذا الموضوع يرجع إلى وجود 
+
+69
+00:05:19,150 --> 00:05:23,310
+كمية كبيرة جدا من الـ yolk sac في عفوا كمية كبيرة 
+
+70
+00:05:23,310 --> 00:05:28,750
+جدا من الـ yolk داخل الـ yolk sac تستخدمها البويضة 
+
+71
+00:05:28,750 --> 00:05:34,160
+ذات الحجم الكبير لعملية التغذية والنمو للحصول على 
+
+72
+00:05:34,160 --> 00:05:38,140
+جنين طبيعي وجنين كامل النمو بينما في الـ human 
+
+73
+00:05:38,140 --> 00:05:43,220
+البويضة الملقحة تتحول إلى embryo الـ embryo ينغمس 
+
+74
+00:05:43,220 --> 00:05:47,100
+في بطانة الرحم الخاصة بالأم مما يسمح له بتكوين 
+
+75
+00:05:47,100 --> 00:05:51,360
+structure بنسميه placenta التي تصبح فيما بعد مصدر 
+
+76
+00:05:51,360 --> 00:05:55,680
+للغذاء مصدر للغذاء فلا داعي ولا حاجة للبويضة 
+
+77
+00:05:55,680 --> 00:05:59,880
+الخاصة بالـ human أن تتغذى وتتخزن تتغذى بنفسها 
+
+78
+00:05:59,880 --> 00:06:04,220
+أو تتخزن كمية كبيرة جدا من الـ yolk في داخلها فبالتالي 
+
+79
+00:06:04,220 --> 00:06:09,360
+الحجم يبقى صغير. إذا كبر الحجم من صغره يعتمد على هل 
+
+80
+00:06:09,360 --> 00:06:12,960
+البويضة بعد الطلقية سوف تُغذي نفسها من نفسها أو 
+
+81
+00:06:12,960 --> 00:06:16,160
+تعتمد على مصدر آخر. إذا تُغذي نفسها من نفسها زي 
+
+82
+00:06:16,160 --> 00:06:21,400
+البويضات بتاعة القيور مثلا فبالتالي لازم تكون كمية 
+
+83
+00:06:21,400 --> 00:06:25,580
+كبيرة جدا من الـ yolk مخزنة بداخل البويضة حتى تسمح 
+
+84
+00:06:25,580 --> 00:06:30,160
+لها بعملية النمو والانقسام. Mammalian cleavage is a
+
+85
+00:06:30,160 --> 00:06:34,900
+prolonged process that typically takes a large 
+
+86
+00:06:34,900 --> 00:06:39,680
+amount of time and requires to transport the early 
+
+87
+00:06:39,680 --> 00:06:44,340
+embryo form its site of fertilization to the site 
+
+88
+00:06:44,340 --> 00:06:48,320
+of implantation. بمعنى آخر أن عملية الـ cleavage 
+
+89
+00:06:48,320 --> 00:06:51,740
+الخاصة بالبويضة الملقحة الخاصة بالماماليا الفديات 
+
+90
+00:06:51,740 --> 00:06:55,160
+تأخذ فترة زمنية طويلة جدا ما بين لحظة الـ 
+
+91
+00:06:55,160 --> 00:06:59,980
+fertilization مرورا بالانقسامات المتتالية ووصولا 
+
+92
+00:06:59,980 --> 00:07:03,900
+إلى منطقة الـ Implantation في بطانة الرحم. هنعرف 
+
+93
+00:07:03,900 --> 00:07:07,720
+جدّيش بتاخد فترة زمنية. the development procedure at
+
+94
+00:07:07,720 --> 00:07:11,280
+the rate of roughly one cleavage division per one
+
+95
+00:07:11,280 --> 00:07:15,500
+day. يعني عملية الانقسام في البويضة الملقحة في أول 
+
+96
+00:07:15,500 --> 00:07:19,400
+يومين بيكون ثابت انقسام واحد كل يوم. بعد كده بعد 
+
+97
+00:07:19,400 --> 00:07:22,880
+اليوم الأول والثاني بشكل أساسي تختلف معدلات 
+
+98
+00:07:22,880 --> 00:07:27,180
+الانقسامات فتصبح متسارعة عشان تصل للعدد المطلوب 
+
+99
+00:07:27,180 --> 00:07:33,620
+من الخلايا. بعد اليوم الثاني أو بعد ما تكوين two 
+
+100
+00:07:33,620 --> 00:07:37,500
+cells خلينا نسميها بشكل أوضح وشكل أدق بيصير في 
+
+101
+00:07:37,500 --> 00:07:40,960
+عندي نوع من أنواع التزامن في الانقسامات بمعنى آخر 
+
+102
+00:07:40,960 --> 00:07:44,160
+أن الخلية في اليوم الأول بتاعة خليتين فبسمّي 
+
+103
+00:07:44,160 --> 00:07:49,540
+الخليتين الـ Blastomere بعد كده الـ Blastomere 
+
+104
+00:07:49,540 --> 00:07:54,360
+هتنقسم إلى تلات خلايا والتلات وكذا هينقسموا يعني 
+
+105
+00:07:54,360 --> 00:07:56,560
+بيصير عندي اتنين الاتنين بيصيروا تلاتة بعدين 
+
+106
+00:07:56,560 --> 00:07:58,740
+بيصيروا أربعة الأربعة بيصيروا ثمانية ثمانية 
+
+107
+00:07:58,740 --> 00:08:02,840
+بيصيروا ستة عشر. لما نصل لمرحلة خلية واحدة تحتوي 
+
+108
+00:08:02,840 --> 00:08:07,400
+بداخلها على ستة عشر خلية بنسمي الـ whole structure 
+
+109
+00:08:07,400 --> 00:08:11,560
+Morula بنسمي الـ whole structure Morula وهذا الكلام 
+
+110
+00:08:11,560 --> 00:08:16,320
+خدناه في المحاضرة السابقة. الخلايا الموجودة بداخل 
+
+111
+00:08:16,320 --> 00:08:20,000
+الخلية الأم أو البويضة الأم إذا كانت تحتوي على 
+
+112
+00:08:20,000 --> 00:08:24,540
+ثمانية لستة عشر. stage the embryo of placental 
+
+113
+00:08:24,540 --> 00:08:27,360
+mammalian enter in the phase called compaction 
+
+114
+00:08:27,360 --> 00:08:31,920
+يعني بمجرد ما تصل عدد الخلايا في الداخل اللي 
+
+115
+00:08:31,920 --> 00:08:36,860
+سميناها embryonic stem cell ثمان خلايا وتبدأ تتزايد 
+
+116
+00:08:36,860 --> 00:08:40,670
+لتصل إلى ستة عشر خلية عشان تعطيني الـ Morula بيصير هذه 
+
+117
+00:08:40,670 --> 00:08:43,570
+المرحلة بنسميها compaction stage شو معنى 
+
+118
+00:08:43,570 --> 00:08:45,450
+compaction stage؟ what's the meaning of 
+
+119
+00:08:45,450 --> 00:08:47,690
+compaction stage؟ what do you know about the
+
+120
+00:08:47,690 --> 00:08:50,730
+compaction stage؟ الـ compaction stage ببساطة جدا 
+
+121
+00:08:50,730 --> 00:08:54,150
+هي مرحلة يتم فيها تداخل الخلايا مع بعض على بعض 
+
+122
+00:08:54,150 --> 00:08:59,930
+لدرجة أنك ما بتقدر تشوف حد كل خلية عن الأخرى أنت 
+
+123
+00:08:59,930 --> 00:09:04,650
+بتلاقيهم كجملة واحدة كتلة واحدة مدمجين مع بعض ومع 
+
+124
+00:09:04,650 --> 00:09:09,490
+بعض ما في حدود ما بين الخلايا ما في خلية تقول والله 
+
+125
+00:09:09,490 --> 00:09:13,770
+أنا هذا الـ outer layer الخاص بها. بتلاقيهم نوع من 
+
+126
+00:09:13,770 --> 00:09:17,470
+أنواع الاندماج. this process which occur 
+
+127
+00:09:17,470 --> 00:09:21,250
+approximately four days after fertilization وهذه 
+
+128
+00:09:21,250 --> 00:09:26,590
+العملية بنسميها cavitation في عملية الـ compaction 
+
+129
+00:09:26,590 --> 00:09:31,980
+بشكل أساسي بيصير اندماج الخلايا مع بعضها البعض ما في 
+
+130
+00:09:31,980 --> 00:09:36,260
+عندي outer layer للخلايا وحدود الخلايا بتصير عندي 
+
+131
+00:09:36,260 --> 00:09:39,840
+junction بين بعض البعض تحت مصطلح tied adhere 
+
+132
+00:09:39,840 --> 00:09:44,180
+through the gap and tight junction and lose their 
+
+133
+00:09:44,180 --> 00:09:48,820
+individual identity individual line when view from
+
+134
+00:09:48,820 --> 00:09:51,480
+the surface. يعني الخلايا بتندمج مع بعض البعض 
+
+135
+00:09:51,480 --> 00:09:55,640
+الخلايا تتداخل مع بعض البعض ما في outer layer أو 
+
+136
+00:09:55,640 --> 00:10:00,100
+outline لكل خلية ما في border لكل خلية بتلاقي 
+
+137
+00:10:00,100 --> 00:10:03,300
+الخلايا اندمجت مع بعض البعض واتصلت مع بعض البعض 
+
+138
+00:10:03,300 --> 00:10:08,680
+طبعا اندماج الخلايا وانغماسها مع بعض البعض المرحلة 
+
+139
+00:10:08,680 --> 00:10:13,000
+كلها بنسميها compaction as phase بينما الـ process 
+
+140
+00:10:13,000 --> 00:10:18,900
+هذه بنسميها cavitation وبتصير في اليوم الرابع من 
+
+141
+00:10:18,900 --> 00:10:22,480
+بعد عملية ال fertilization at this stage المقصود
+
+142
+00:10:22,480 --> 00:10:26,580
+فيه ال competition stage the embryo as a whole is no
+
+143
+00:10:26,580 --> 00:10:30,720
+plastocyst لما بعد يصير عندي أربع أيام ويصير 
+
+144
+00:10:30,720 --> 00:10:34,380
+الاندماج المتميز بين الخلايا يعني تصير مرحلة ال
+
+145
+00:10:34,380 --> 00:10:40,520
+cavitation بسمي ال structure ككل بسميه blastocyst
+
+146
+00:10:40,520 --> 00:10:45,500
+بسميه blastocyst  خلية أو صورة بتوضح الكلام هذا في
+
+147
+00:10:45,500 --> 00:10:49,890
+عندي هنا وهي عبارة عن بويضة لقحت أعطتني في اليوم
+
+148
+00:10:49,890 --> 00:10:53,950
+الأول خليتين كانت one cell سميتها as I got بعدين
+
+149
+00:10:53,950 --> 00:10:56,870
+اتقسمت التلت ل two cells هذا في اليوم الأول في
+
+150
+00:10:56,870 --> 00:10:59,730
+اليوم الثاني أدتني أربع خلايا كل خلية بتسميها plus
+
+151
+00:10:59,730 --> 00:11:04,110
+to minus في اليوم الثاني ونص جريبا علشان نتصل
+
+152
+00:11:04,110 --> 00:11:08,030
+اليوم الثالث وهي 8 من 8 ل 16 خلية في اليوم الثالث
+
+153
+00:11:08,030 --> 00:11:12,410
+16 خلية اللي بتسميها morula في اليوم الرابع تصير
+
+154
+00:11:12,410 --> 00:11:17,240
+58 خلية بتسميها plus to sixth في اليوم الخامس
+
+155
+00:11:17,240 --> 00:11:21,820
+بتنقسم إلى 107 خلية بنسميها blastocyst أيضًا إذا
+
+156
+00:11:21,820 --> 00:11:27,280
+المورولا بتظهر في اليوم الثالث من التخصيب وتحتوي
+
+157
+00:11:27,280 --> 00:11:32,940
+على أكثر من 8 خلايا كحد أدنى وحد أقصى 16 خلية
+
+158
+00:11:32,940 --> 00:11:37,640
+blastocyst بتزيد عن 16 خلية وكل هذه المراحل بتكون
+
+159
+00:11:37,640 --> 00:11:40,700
+مازالت محاطة بالـ zona pellucida
+
+160
+00:11:42,660 --> 00:11:45,860
+At the beginning of cleavage, the zona is still in
+
+161
+00:11:45,860 --> 00:11:52,300
+case or in covering the
+
+162
+00:11:52,300 --> 00:11:56,120
+cell plus الـ cell المقصود فيها الخلايا الداخلية
+
+163
+00:11:56,120 --> 00:11:58,760
+ال embryonic stem cell يعني ال embryonic stem cell
+
+164
+00:11:58,760 --> 00:12:01,420
+مازالت ضمن محفظة واحدة اللي هي ال zona pellucida
+
+165
+00:12:01,420 --> 00:12:04,740
+وفي الخارج يحيط بيها طبقة رقيقة من ال corona
+
+166
+00:12:04,740 --> 00:12:08,920
+radiata ال corona radiata تبقى كما هي حتى اليوم
+
+167
+00:12:08,920 --> 00:12:12,670
+الثاني بعد اليوم الثاني من عملية الإنقسامات تبدأ
+
+168
+00:12:12,670 --> 00:12:17,970
+بالاختفاء تدريجيًا رغم إن ال corona radiata منها
+
+169
+00:12:17,970 --> 00:12:21,310
+removing بالـ denudation ولكن ما بنقدر نعمل
+
+170
+00:12:21,310 --> 00:12:24,530
+removing completely بلقى جزء منها ما زال موجود
+
+171
+00:12:24,530 --> 00:12:28,740
+الـ zona pellucida remained intact. However, until the
+
+172
+00:12:28,740 --> 00:12:31,140
+embryo arrives to the uterus
+
+173
+00:12:40,420 --> 00:12:43,160
+وخذوا بالكم مهم جدا .. هنعرف كمان شوية شو هي
+
+174
+00:12:43,160 --> 00:12:46,000
+أهمية الـ zona pellucida ده مهم جدا الـ zona pellucida ده
+
+175
+00:12:46,000 --> 00:12:51,020
+تبقى عشان ما يصيرش تفتت للخلايا ويصير تفرق للخلايا
+
+176
+00:12:51,020 --> 00:12:54,980
+وبالتالي أفقد الجنين لأنه خلال عملية انتقال البيضة
+
+177
+00:12:54,980 --> 00:12:58,800
+المخصبة بحكي بشكل طبيعي من قناة فالوب إلى الرحم
+
+178
+00:12:58,800 --> 00:13:04,300
+بتمر بعوائق كثيرة أقلها حركة السيليا فتصور لو أن
+
+179
+00:13:04,300 --> 00:13:07,980
+هذه الخلايا الـ embryonic stem cell اللي مش موجود
+
+180
+00:13:07,980 --> 00:13:11,860
+حولها الزونا بيلوسيدا، هيصيرها تفتت وتفرق، بالتالي،
+
+181
+00:13:11,860 --> 00:13:15,680
+هيصير المحصلة أنها نهائية صفر مافي عند الـ embryo
+
+182
+00:13:15,680 --> 00:13:19,340
+completely embryo الـ embryo تبقى في جزء الأنبوبي
+
+183
+00:13:19,340 --> 00:13:24,200
+من اليوتران تيوب ثلاثة أيام، يعني ببدأ في منطقة
+
+184
+00:13:24,200 --> 00:13:27,840
+الأنبوبي الخاصة بالفلوبيان تيوب ثلاثة أيام، يعني
+
+185
+00:13:27,840 --> 00:13:31,740
+البويضة المخصبة تجلس في فلوبيان تيوب، وهي المرحلة
+
+186
+00:13:31,740 --> 00:13:34,980
+اللي هتنتقل منها، المسافة اللي هتقطعها، حوالي ثلاثة
+
+187
+00:13:34,980 --> 00:13:39,120
+أيام. It then crossed the isthmus portion of the
+
+188
+00:13:39,120 --> 00:13:42,180
+tube in the little of eight hours. يعني بويضة
+
+189
+00:13:42,180 --> 00:13:45,160
+خصبت في الطولة الأول الأعلى من ال fallopian tube،
+
+190
+00:13:45,160 --> 00:13:49,140
+هذا في الوضع الطبيعي، هتستمر وهتتدهرج لمدة زمنية
+
+191
+00:13:49,140 --> 00:13:52,840
+تقدر بثلاثة أيام، علشان تقطع طول ال fallopian tube
+
+192
+00:13:53,340 --> 00:13:56,560
+هتصل إلى منطقة المضيق وهو المنطقة التي تفصل
+
+193
+00:13:56,560 --> 00:13:59,700
+fallopian tube عن بداية الرحم والتي سميتها في ال
+
+194
+00:13:59,700 --> 00:14:04,020
+chapter الأول isthmus عشان تخترق ال isthmus وتعمل
+
+195
+00:14:04,020 --> 00:14:07,360
+scabbing لل isthmus أو entering لل isthmus تأخذ
+
+196
+00:14:07,360 --> 00:14:11,780
+فقط 8 ساعات. Under the influence of progesterone
+
+197
+00:14:11,780 --> 00:14:16,480
+neutral tube junction relaxation contraction
+
+198
+00:14:16,480 --> 00:14:20,720
+relaxation those allow the embryo to enter the
+
+199
+00:14:20,720 --> 00:14:23,860
+uterine cavity. تحت تأثير الـ Progesterone الذي
+
+200
+00:14:23,860 --> 00:14:27,960
+يُفرز بشكل مستمر تحت تأثير انقباض وارتخاء العضلات
+
+201
+00:14:27,960 --> 00:14:32,840
+الخاصة بالرحم والأنابيب المتعلقة بالجهاز الـ
+
+202
+00:14:32,840 --> 00:14:38,280
+genital الـ reproductive system يسمح بدخول ال
+
+203
+00:14:38,280 --> 00:14:44,680
+embryo إلى الرحم، طالما دخل الرحم، إذن هيتكون معدل
+
+204
+00:14:44,680 --> 00:14:49,750
+عملية ال implantation. Couples of day من ستة إلى ستة
+
+205
+00:14:49,750 --> 00:14:53,110
+تقريبًا days after fertilization the embryo implanted
+
+206
+00:14:53,110 --> 00:14:56,150
+in the mid portion of the posterior wall of the
+
+207
+00:14:56,150 --> 00:15:01,310
+uterus. يعني بعد حوالي ستة أيام على الأقل إلى ثلاثة
+
+208
+00:15:01,310 --> 00:15:05,110
+أيام على الأكثر من عملية ال fertilization المفروض
+
+209
+00:15:05,110 --> 00:15:10,250
+المفروض يكون الجنين قطع كل المسافة الخاصة بال
+
+210
+00:15:10,250 --> 00:15:14,490
+Fallopian tube وقطع الإزمس ووصل لمنطقة معينة عشان
+
+211
+00:15:14,490 --> 00:15:18,440
+يصيله implantation فيهبط في الرحم وفي جدار الرحم
+
+212
+00:15:18,440 --> 00:15:22,500
+وفي المنطقة بيسموها بالضبط middle portion of
+
+213
+00:15:22,500 --> 00:15:27,120
+posterior wall of the uterus. يعني لو صارت تلقيح
+
+214
+00:15:27,120 --> 00:15:34,040
+يوم 13 هتحسب الزوجة 13 14 15 16 17 18 19 20 في
+
+215
+00:15:34,040 --> 00:15:37,960
+اليوم ال 20 المفروض الجنين يكون صار له implantation
+
+216
+00:15:37,960 --> 00:15:41,760
+هذا الوضع الطبيعي الوضع الطبيعي علشان كده معظم
+
+217
+00:15:41,760 --> 00:15:45,970
+المراكز التي بتعمل حقن مجهري بتطلع الجنين في اليوم
+
+218
+00:15:45,970 --> 00:15:49,050
+بعد اليوم الثالث يا إما الرابع، يا إما الخامس، يا
+
+219
+00:15:49,050 --> 00:15:53,610
+إما السادس علشان يحاكي الوضع الطبيعي during this
+
+220
+00:15:53,610 --> 00:15:57,330
+time. خلال هذه الأيام، الـ6 إلى الـ8 أيام بعد عملية
+
+221
+00:15:57,330 --> 00:16:00,150
+ال fertilization الـ zona pellucida بيصير فيها
+
+222
+00:16:00,150 --> 00:16:04,690
+تغير في تركيبها علشان تلائم المرحلة الجديدة تغير
+
+223
+00:16:04,690 --> 00:16:10,650
+في تركيبها تبدأ يصير فيها تغير علشان تبدأ يصيلها
+
+224
+00:16:10,650 --> 00:16:14,940
+عملية hatching. شو يعني hatching؟ يعني opening طبعا
+
+225
+00:16:14,940 --> 00:16:18,580
+أتروا contribution from the blastomere and the
+
+226
+00:16:18,580 --> 00:16:20,900
+maternal reproductive tissue and this change
+
+227
+00:16:20,900 --> 00:16:24,120
+facilitated the transport and differentiation of
+
+228
+00:16:24,120 --> 00:16:26,560
+the embryo. هذه مهمة جدا التغييرات التي بتصير في
+
+229
+00:16:26,560 --> 00:16:29,120
+الزونا بيلوسيدا لأن المفروض الزونا بيلوسيدا ما
+
+230
+00:16:29,120 --> 00:16:33,440
+تبقى rigid ما تبقى hard لفترة زمنية طويلة مهمة في
+
+231
+00:16:33,440 --> 00:16:38,640
+مرحلة الانتقال ولكن بمجرد حدوث ووصول إلى مرحلة ال
+
+232
+00:16:38,640 --> 00:16:42,950
+implantation لازم يصير فيها changing أو يصير فيها
+
+233
+00:16:42,950 --> 00:16:49,310
+thinning علشان تبدأ وتسمح لل embryo بالخروج طبعا
+
+234
+00:16:49,310 --> 00:16:54,510
+بعد ما يصل ال embryo لبطانة الرحم أو الرحم أو
+
+235
+00:16:54,510 --> 00:16:57,590
+تجويف الرحم تبدأ ال zona pellucida بتعمل hatching
+
+236
+00:16:57,590 --> 00:17:01,610
+أو تعمل removing أو تعمل opening تمهيد لل
+
+237
+00:17:01,610 --> 00:17:06,110
+implantation وعملية وجود ثقوب وفتح ثقوب في zona
+
+238
+00:17:06,110 --> 00:17:10,270
+pellucida بنسمي هذه العملية hatching أو بنسميها
+
+239
+00:17:10,270 --> 00:17:16,750
+blastocyst hatching. Hatching يعني poor formation
+
+240
+00:17:16,750 --> 00:17:21,150
+متى بيبدأ الهاتشينج؟ بعد ثمانية أيام من عملية
+
+241
+00:17:21,150 --> 00:17:26,810
+التلقيح وذلك بمجرد وصول الويضة الملقحة التي صارت
+
+242
+00:17:26,810 --> 00:17:30,490
+embryo إلى تجويف الرحم. A small region of the
+
+243
+00:17:30,490 --> 00:17:33,150
+navel used a huge one directly over the inner cell
+
+244
+00:17:33,150 --> 00:17:37,250
+mass in the mammalian for example, the sole and
+
+245
+00:17:37,250 --> 00:17:42,240
+the blastocyst embedded from the hole. يعني بمعنى آخر
+
+246
+00:17:42,240 --> 00:17:45,400
+إن الـ zona pellucida ده كمية كبيرة ومناطق معينة من
+
+247
+00:17:45,400 --> 00:17:50,280
+الـ zona pellucida ده تتحطم تتفتح هذا يسمح بيصيرها
+
+248
+00:17:50,280 --> 00:17:54,540
+dissolving. بمعنى آخر يسمح بخروج الـ blastocyst و
+
+249
+00:17:54,540 --> 00:18:00,040
+يحدث لها direct contact مع البطانة الرحم مما يمهد
+
+250
+00:18:00,040 --> 00:18:04,060
+لعملية ال implantation. يعني كأنه بيصير hole أو
+
+251
+00:18:04,060 --> 00:18:10,040
+pores في الرحم في الرحم بيصير عندي حاجة بتسميها The
+
+252
+00:18:10,040 --> 00:18:13,260
+trophoectoderm projections then contact with the
+
+253
+00:18:13,260 --> 00:18:16,180
+endometrium epithelium cell as the process of
+
+254
+00:18:16,180 --> 00:18:19,580
+implantation. الـ trophoectoderm هي عبارة عن نوع من
+
+255
+00:18:19,580 --> 00:18:22,260
+أنواع الخلايا الموجودة في الـ embryo، إذا بتذكروا
+
+256
+00:18:22,260 --> 00:18:26,600
+في المحاضرة السابقة الـ trophoectoderm و endoderm
+
+257
+00:18:26,600 --> 00:18:30,860
+و mesoderm. هذا الـ trophoectoderm هي التي تبدأ كبروز
+
+258
+00:18:30,860 --> 00:18:34,420
+تتحد مع بطانة الرحم، علشان تبدأ تمهيد
+
+259
+00:18:34,420 --> 00:18:37,800
+للـ implantation. في enzymatic activity around the
+
+260
+00:18:37,800 --> 00:18:41,400
+enter trophoplast soon beginning to dissolve the
+
+261
+00:18:41,400 --> 00:18:44,180
+rest of the zona pellucida. بعد ما تبدأ ال
+
+262
+00:18:44,180 --> 00:18:48,060
+projection تظهر وتصير contact مع ال endometrium
+
+263
+00:18:48,060 --> 00:18:52,080
+of the epithelium cell. في بعض التغيرات الإنزيمية
+
+264
+00:18:52,080 --> 00:18:56,560
+والنشاطات الإنزيمية التي تبدأ في الحدوث مما يمهد
+
+265
+00:18:56,560 --> 00:19:00,980
+إلى اختفاء ما تبقى من ال zona pellucida وتحللها
+
+266
+00:19:00,980 --> 00:19:07,270
+هذا بالنسبة إلى عملية الحطن. كيف تتم عملية انتقال
+
+267
+00:19:07,270 --> 00:19:13,290
+البويضة بعد عملية التلقيح الطبيعي في الصورة
+
+268
+00:19:13,290 --> 00:19:16,130
+التالية بتوضح عند البويضة صار لها عملية
+
+269
+00:19:16,130 --> 00:19:20,130
+implantation. اعفوا صار لها عملية ovulation ثم في
+
+270
+00:19:20,130 --> 00:19:23,830
+النهاية implantation. ال ovulation للبويضة البويضة
+
+271
+00:19:23,830 --> 00:19:28,550
+صار لها بويضة طبعا ناضجة في المبيض صار لها ovulation
+
+272
+00:19:28,550 --> 00:19:32,030
+في صار contact بين ال male وال female صار عند ال
+
+273
+00:19:32,030 --> 00:19:36,630
+fertilization الفيرتاليزيشن صار عندي 2 nuclei فداني
+
+274
+00:19:36,630 --> 00:19:41,610
+الزيجوت تطورت من مادة إلى تكوين 1 cell بعدين 2
+
+275
+00:19:41,610 --> 00:19:46,730
+cell بعدين 4 cell بعدين 8 cell بعدين morula هي من
+
+276
+00:19:46,730 --> 00:19:51,090
+أكثر من 8 خلايا إلى 16 خلية بعدين ال blastocyst
+
+277
+00:19:51,090 --> 00:19:56,350
+بعدين بعد 8 أيام صار عملية ال implantation في جدار
+
+278
+00:19:56,350 --> 00:20:02,610
+الرحم في جدار الرحم هذه عبارة عن الصور التي تحدد أو
+
+279
+00:20:02,610 --> 00:20:06,090
+الصورة التي تحدد مراحل عملية انتقال البويضة بعد
+
+280
+00:20:06,090 --> 00:20:09,270
+التخصيب من ال fallopian tube إلى بطانة الرحم. 
+
+281
+00:20:09,270 --> 00:20:13,450
+طبعا الصورة السفلية بتحدد كيف بيصير عندي عملية
+
+282
+00:20:13,450 --> 00:20:18,530
+removing للـ half of number of chromosome من أجل
+
+283
+00:20:18,530 --> 00:20:23,110
+ظهور الـ first و second polar body لأنه قلنا أن أول
+
+284
+00:20:23,110 --> 00:20:27,370
+علامة من عمليات نجاح الحقن المجهري أو عمليات
+
+285
+00:20:27,370 --> 00:20:32,190
+التلقيح بشكل عام هي ظهور الـ second polar body طيب
+
+286
+00:20:32,190 --> 00:20:35,810
+الـ Zona pellucida حكينا عنها بكمية كبيرة جدا ما هي
+
+287
+00:20:35,810 --> 00:20:39,850
+أهميتها؟ الـ Zona pellucida لها أهمية كبيرة جدا شو
+
+288
+00:20:39,850 --> 00:20:43,870
+هي أهميتها؟ لماذا تستخدم؟ وكيف تستخدم؟ الـ
+
+289
+00:20:43,870 --> 00:20:47,670
+Zona pellucida هي عبارة عن طبقة رقيقة في البداية
+
+290
+00:20:47,670 --> 00:20:51,770
+تحيط بالبويضة لتحمل البويضة وتسهل عملية ال
+
+291
+00:20:51,770 --> 00:20:55,480
+connection ما بين البويضة والوسط الخارجي أو المحيط
+
+292
+00:20:55,480 --> 00:20:59,700
+الخارجي أو البيئة الخارجية كما أسلفنا سابقًا هل
+
+293
+00:20:59,700 --> 00:21:03,620
+لها عوامل أخرى وظائف أخرى؟ أكيد لها وظائف أخرى
+
+294
+00:21:03,620 --> 00:21:06,720
+وظائف شتى الـ Zona pellucida بنرمز إليها بالـ ZP
+
+295
+00:21:06,720 --> 00:21:10,300
+وتتكون في الغالب من sulphated glycoprotein يعني
+
+296
+00:21:10,300 --> 00:21:14,440
+بتتكون من protein plus carbohydrate الـ
+
+297
+00:21:14,440 --> 00:21:16,720
+Zona pellucida بتلعب دور كبير جدا في عملية ال
+
+298
+00:21:16,720 --> 00:21:19,940
+protection بتلعب دور كبير جدا في عملية الـ embryo
+
+299
+00:21:19,940 --> 00:21:25,700
+development بتلعب دور كبير جدا في عملية step by
+
+300
+00:21:25,700 --> 00:21:29,000
+step أو point by point أول حاجة الـ function
+
+301
+00:21:29,000 --> 00:21:32,080
+الأساسية للـ Zona pellucida بعد الـ fertilization
+
+302
+00:21:32,080 --> 00:21:35,860
+إنها بتعمل protection للـ embryo وبتعمل إليه
+
+303
+00:21:35,860 --> 00:21:39,480
+maintenance of its integrity مهم جدا لأن الـ
+
+304
+00:21:39,480 --> 00:21:44,420
+Zona pellucida إنها بتحمل الجنين بتحمل خلايا
+
+305
+00:21:44,420 --> 00:21:48,240
+الجنينية ما بتخلي الخلايا الجنينية متفرقة مبعثرة
+
+306
+00:21:48,240 --> 00:21:53,190
+فبالتالي تبقى الـ Zona pellucida أشهر وظيفة لها بعد ال
+
+307
+00:21:53,190 --> 00:21:56,190
+fertilization هي حماية الجنين والمحافظة على
+
+308
+00:21:56,190 --> 00:22:01,170
+التراكيب الداخلية الخاصة فيه الـ Zona pellucida هي التي
+
+309
+00:22:01,170 --> 00:22:05,250
+تسمح بعملية الـ maturation للـ oocyte في البداية
+
+310
+00:22:05,250 --> 00:22:12,160
+الـ Zona pellucida تعتبر عامل مهم جدا حيث تسمح لتمام
+
+311
+00:22:12,160 --> 00:22:15,360
+عملية الـ Fertilization من خلال وجود Receptor خاصة
+
+312
+00:22:15,360 --> 00:22:18,140
+بالـ spermatozoa هذه الـ Receptor موجودة في
+
+313
+00:22:18,140 --> 00:22:20,900
+الـ Zona pellucida ده الـ three لأن قلنا الـ Zona pellucida ده
+
+314
+00:22:20,900 --> 00:22:24,540
+أكثر من طبقة الـ Zona pellucida ده هي التي تسمح
+
+315
+00:22:24,540 --> 00:22:28,260
+بعملية الـ Acrosome reaction يعني عملية ال
+
+316
+00:22:28,260 --> 00:22:32,260
+fertilization مش sperm ارتبط ببويضة فقط لا sperm
+
+317
+00:22:32,260 --> 00:22:36,120
+وصلت للبويضة ارتبط بالـ Receptor نشطت البويضة الـ
+
+318
+00:22:36,120 --> 00:22:39,750
+Acrosome reaction علشان يساعد على الاختراق فمهم جدا
+
+319
+00:22:39,750 --> 00:22:43,030
+after fertilization the modified Zona pellucida
+
+320
+00:22:43,030 --> 00:22:47,090
+prevent any additional sperm from the arrival to
+
+321
+00:22:47,090 --> 00:22:52,030
+the zygote or another penetration يعني شفنا
+
+322
+00:22:52,030 --> 00:22:55,190
+وظيفتها قبل الـ fertilization وشفنا وظيفتها بعد الـ
+
+323
+00:22:55,190 --> 00:22:58,210
+fertilization قبل الـ fertilization حماية البويضة
+
+324
+00:22:58,210 --> 00:23:03,950
+تطوير البويضة تسهيل عملية الـ fertilization كمان
+
+325
+00:23:03,950 --> 00:23:07,450
+تنشيط الـ Acrosome reaction هذا كلها before fertilization
+
+326
+00:23:07,450 --> 00:23:10,960
+after fertilization تعمل على منع الـ polyspermia
+
+327
+00:23:10,960 --> 00:23:17,080
+injection أو fertilize the oocyte by two sperms من
+
+328
+00:23:17,080 --> 00:23:20,460
+خلال تغيير الـ Receptor أيضًا بتحافظ على الجنين زي
+
+329
+00:23:20,460 --> 00:23:22,980
+ما قلنا و هي الـ main function of Zona pellucida
+
+330
+00:23:22,980 --> 00:23:27,500
+خلال المراحل المتقدمة أو المراحل المبكرة من مراحل
+
+331
+00:23:27,500 --> 00:23:34,060
+انقسام الجنين الـ Zona pellucida بتعمل كـ pores أو كشرط
+
+332
+00:23:34,060 --> 00:23:39,880
+مرور بالضبط تتحكم بما يدخل إلى الخلية وتمنع المواد
+
+333
+00:23:39,880 --> 00:23:43,360
+الأخرى من الدخول إلى الخلية وذلك بناء على احتياج
+
+334
+00:23:43,360 --> 00:23:48,060
+الخلية بالضبط تعمل زي إشارة المرور تسمح بدخول
+
+335
+00:23:48,060 --> 00:23:52,440
+مواد وتمنع دخول مواد أخرى بناء على احتياج الجنين
+
+336
+00:23:53,610 --> 00:23:57,350
+طبعا بسبب عدم وجود أو فقدان الـ Zona pellucida
+
+337
+00:23:57,350 --> 00:24:00,250
+الحالية بتسميها histocompatibility وهي نوع من
+
+338
+00:24:00,250 --> 00:24:02,530
+أنواع الـ human leukocyte antigen الـ
+
+339
+00:24:02,530 --> 00:24:06,190
+Zona pellucida serve as immunological pairs between
+
+340
+00:24:06,190 --> 00:24:10,590
+mother and the antigenetical different embryo بسبب
+
+341
+00:24:10,590 --> 00:24:13,170
+فقدان الـ Zona pellucida الـ human leukocyte
+
+342
+00:24:13,170 --> 00:24:17,670
+antigen فبتعمل كحاجز مناعي يحمل جنين ويحمل أم
+
+343
+00:24:17,670 --> 00:24:21,770
+Zona pellucida بتعمل على تسهيل الـ differentiation
+
+344
+00:24:21,770 --> 00:24:27,680
+للـ trophoplastic cell it is normally prevent
+
+345
+00:24:27,680 --> 00:24:31,120
+premature implantation of the cleavage embryo into
+
+346
+00:24:31,120 --> 00:24:33,380
+the wall of the uterine tube طبعا الـ
+
+347
+00:24:33,380 --> 00:24:38,160
+Zona pellucida وجودها ووجودها بشكل hard إلى حد ما
+
+348
+00:24:38,160 --> 00:24:41,220
+في أول أربعة أيام إلى ثلاثة أيام من الـ fertilization
+
+349
+00:24:41,220 --> 00:24:45,720
+تمنع تحافظ على الجنين وتمنع حدوث implantation مبكر
+
+350
+00:24:45,720 --> 00:24:49,740
+في منطقة غير معدة زي حدوث الـ implantation في منطقة
+
+351
+00:24:49,740 --> 00:24:52,520
+الـ fallopian tube مما يؤدي إلى حدوث ectopic
+
+352
+00:24:52,520 --> 00:24:55,250
+pregnancy يعني أحد أسباب الـ ectopic pregnancy
+
+353
+00:24:55,250 --> 00:25:01,650
+الخلل في الـ Zona pellucida طيب وصلنا لحرفنا أهمية
+
+354
+00:25:01,650 --> 00:25:05,190
+الـ Zona pellucida الـ function الخاصة فيها بعد كده
+
+355
+00:25:05,190 --> 00:25:10,530
+كيف يمكن أن نعمل على ترقيق الـ Zona pellucida بمعنى
+
+356
+00:25:10,530 --> 00:25:14,210
+آخر في الحقن المجهري جاب العملية الـ embryo
+
+357
+00:25:14,210 --> 00:25:17,750
+transfer أو إرجاع الـ embryo لازم أعمل حاجة بنسميها
+
+358
+00:25:17,750 --> 00:25:22,150
+thinning يعني بمعنى آخر ترفيه أو ترقيق الـ
+
+359
+00:25:22,150 --> 00:25:25,370
+Zona pellucida ليه بنرقيق الـ Zona pellucida؟ علشان
+
+360
+00:25:25,370 --> 00:25:29,030
+أسمح للـ Zona pellucida إنها تتلاشى ببساطة جدا
+
+361
+00:25:29,030 --> 00:25:32,990
+وبسهولة جدا دون تأخير وتساهم في عملية الـ
+
+362
+00:25:32,990 --> 00:25:37,190
+Implantation حاجة بنسميها Assisted Hatching in Exit
+
+363
+00:25:37,190 --> 00:25:40,890
+يا إما بعمل Thinning، ترقيق، يا إما بعمل  Pouring،
+
+364
+00:25:40,890 --> 00:25:45,010
+هنشوف كيف بعمل Pouring الـ Implantation خلال الحقن
+
+365
+00:25:45,010 --> 00:25:50,990
+المجهري يحتاج إلى عملية بنسميها Hatching technique وهي
+
+366
+00:25:50,990 --> 00:25:55,430
+عمل ثقوب في جدار الـ Zona pellucida وهذا الثقوب ما
+
+367
+00:25:55,430 --> 00:25:58,670
+بتكون غائرة أو بعض الأحيان بتسميها filling of
+
+368
+00:25:58,670 --> 00:26:02,350
+Zona pellucida failure of the embryo to escape the
+
+369
+00:26:02,350 --> 00:26:05,390
+Zona pellucida is believed to be related to low
+
+370
+00:26:05,390 --> 00:26:08,650
+implantation rate for poor prognosis patients and
+
+371
+00:26:08,650 --> 00:26:14,620
+the main goal of assisted hatching is overcome this
+
+372
+00:26:14,620 --> 00:26:19,620
+obstacle يعني بيقول لي ببساطة جدا أن في حالات يكون
+
+373
+00:26:19,620 --> 00:26:25,580
+الإجراء فشل في الحصول على جنين صحيح أو جنين سليم
+
+374
+00:26:25,580 --> 00:26:28,100
+بعد عملية الـ implantation بعد عملية ال
+
+375
+00:26:28,100 --> 00:26:32,630
+fertilization وبعد عملية الـ embryo transfer بكون
+
+376
+00:26:32,630 --> 00:26:37,270
+سببها بشكل أساسي أن Zona pellucida فشلت في التكسّر
+
+377
+00:26:37,270 --> 00:26:42,590
+أو Zona pellucida ما زالت قوية صلبة منعت الجنين من
+
+378
+00:26:42,590 --> 00:26:46,530
+الخروج فهذا بنسميها embryo to escape prevent the
+
+379
+00:26:46,530 --> 00:26:49,810
+embryo or failure the embryo to escape from
+
+380
+00:26:49,810 --> 00:26:53,670
+Zona pellucida بقى الـ embryo محبوس داخل Zona pellucida
+
+381
+00:26:53,670 --> 00:26:58,190
+Zona pellucida بقيت كما هي قوية لا تسمح بخروج الـ
+
+382
+00:26:58,190 --> 00:27:01,470
+Embryo فبالتالي فشلت عملية الحقن المجهري في الوصول
+
+383
+00:27:01,470 --> 00:27:06,910
+إلى الـ True Embryo داخل الرحم فبالتالي ممكن أن
+
+384
+00:27:06,910 --> 00:27:10,110
+أتغلب على هذا الموضوع من خلال عملية قوية جدا
+
+385
+00:27:10,110 --> 00:27:16,230
+بنسميها Assisted Hatching حاجة برمز لها بالرمز AH
+
+386
+00:27:16,230 --> 00:27:21,530
+طبعا هذه العملية بتحدث في الـ Assisted Reproductive
+
+387
+00:27:21,530 --> 00:27:25,490
+Technology عملية مهمة جدا بتصير من خلالها عمل pores
+
+388
+00:27:25,490 --> 00:27:27,890
+في الـ Zona pellucida إما هذه الـ pores بتكون
+
+389
+00:27:27,890 --> 00:27:31,410
+mechanical pore أو chemical pore يعني ممكن أستخدم
+
+390
+00:27:31,410 --> 00:27:35,950
+مواد كيميائية وأنيمات أو ممكن أستخدم طرق
+
+391
+00:27:35,950 --> 00:27:39,610
+ميكانيكية باستخدام الـ injection needle و هنشوفها
+
+392
+00:27:39,610 --> 00:27:42,830
+كمان شوية كيف أنا ممكن أستخدم الـ injection needle
+
+393
+00:27:43,590 --> 00:27:48,050
+إذا الـ Assisted Hatching في الإجزي بيصير بعد ال
+
+394
+00:27:48,050 --> 00:27:51,410
+fertilization بعد اليوم الخامس من الـ fertilization
+
+395
+00:27:51,410 --> 00:27:53,490
+يعني لو صار الـ fertilization والـ injection في
+
+396
+00:27:53,490 --> 00:27:57,010
+اليوم الأول يعني المفروض تصير في اليوم الخامس وهو
+
+397
+00:27:57,010 --> 00:27:59,810
+يوم الرابع مثلا إذا كان يوم السبت هتصير يوم
+
+398
+00:27:59,810 --> 00:28:03,550
+الرابع وظيفتها أن تعمل pores في Zona pellucida
+
+399
+00:28:03,550 --> 00:28:07,270
+علشان تسمح للجنين بالخروج وأخذ دقيقته ونقله إلى
+
+400
+00:28:07,270 --> 00:28:11,870
+الرحم هل كل الحالات أعملها Assisted Hatching ولا
+
+401
+00:28:11,870 --> 00:28:16,350
+حالات معينة؟ في حالات معينة مهم جدا بل لازب يجب
+
+402
+00:28:16,350 --> 00:28:20,910
+بشكل واجب أن يعمل Assisted Hatching قبل ما يعمل
+
+403
+00:28:20,910 --> 00:28:25,090
+embryo transfer من أشهر هذه الحالات السيدات اللي
+
+404
+00:28:25,090 --> 00:28:28,730
+عندهم recurrent failure of embryo implantation
+
+405
+00:28:28,730 --> 00:28:32,150
+after embryo transfer يعني عند سيدة خضعت للإجزي
+
+406
+00:28:32,150 --> 00:28:36,170
+ثلاث أربع أو خمس مرات كل مرة برجع جنين بيصير عنده
+
+407
+00:28:36,170 --> 00:28:39,030
+فشل في الـ implantation فبالتالي النتيجة negative
+
+408
+00:28:39,480 --> 00:28:42,220
+رجعت الجنين لدورة ثانية، فشل في الـ Implantation
+
+409
+00:28:42,220 --> 00:28:45,500
+النتيجة نيجاتيف وهي نتيجة البيتا الـ hCG فهذا معناه
+
+410
+00:28:45,500 --> 00:28:48,020
+أن الـ Zona pellucida ما صار فيها dissolving،
+
+411
+00:28:48,020 --> 00:28:50,720
+partial dissolving فبالتالي ما صار Implantation
+
+412
+00:28:50,720 --> 00:28:55,440
+فلازم أعمل Assisted Hatching جاب العملية للـ transfer
+
+413
+00:28:55,440 --> 00:28:59,220
+الـ embryo exhibiting thickened Zona pellucida و لا
+
+414
+00:28:59,220 --> 00:29:04,240
+بحكم لجد Zona pellucida very thick مقاومة لعملية ال
+
+415
+00:29:04,240 --> 00:29:08,540
+penetration فلازم أعمل Hatching السيدات اللي عندهم
+
+416
+00:29:08,540 --> 00:29:12,260
+advanced age أكثر من 37 سنة السيدات اللي عندهم
+
+417
+00:29:12,260 --> 00:29:16,580
+مستوى الـ FSH عالي جدا السيدات .. الـ cycle اللي
+
+418
+00:29:16,580 --> 00:29:18,480
+بدأت من الـ cryopreservation شو يعني cryopreservation؟
+
+419
+00:29:18,480 --> 00:29:21,160
+أن السيدة خضعت لـ protocol
+
+420
+00:29:21,160 --> 00:29:26,500
+stimulation أخرجت 35 بويضة حُقّنت 10 بويضات والباقي 
+
+421
+00:29:26,500 --> 00:29:32,280
+عملتلهم preservation جمّعتهم الدورة التانية مش
+
+422
+00:29:32,280 --> 00:29:35,940
+هتطبطب تخضع لعملية ovulation أو مش هتخضع لعملية
+
+423
+00:29:35,940 --> 00:29:40,040
+stimulation فبضطر باخد من البويضات اللي مخزنة فهذه
+
+424
+00:29:40,040 --> 00:29:43,280
+البويضات طالما مخزنة إذا صار في تغير في تركيب
+
+425
+00:29:43,280 --> 00:29:46,480
+الـ zona pellucida في الـ membrane فبعد عملية الحقل
+
+426
+00:29:46,480 --> 00:29:50,880
+لازم أعمل assist hatching علشان أسمح للـ embryo
+
+427
+00:29:50,880 --> 00:29:56,540
+بالخروج بكل بساطة كيف تتم عملية zona pellucida
+
+428
+00:29:56,540 --> 00:30:00,210
+assist hatching أو zona pellucida thinning؟ ترفيه
+
+429
+00:30:00,210 --> 00:30:03,910
+الـ zona pellucida لما اقول thinning بيكون مش كاملة مش
+
+430
+00:30:03,910 --> 00:30:07,810
+completely لأ partially completely لأ partially
+
+431
+00:30:07,810 --> 00:30:12,030
+because thinning partially أو عمل عدد معين من ال
+
+432
+00:30:12,030 --> 00:30:16,770
+pores أو الـ holes zona pellucida removal total
+
+433
+00:30:16,770 --> 00:30:20,050
+zona pellucida removal before embryo transfer has
+
+434
+00:30:20,050 --> 00:30:23,690
+been expected to bring out closer contact and
+
+435
+00:30:23,690 --> 00:30:27,350
+communication of the trophoectoderm of the
+
+436
+00:30:27,350 --> 00:30:31,090
+blastocyst with the endometrium thereby improving
+
+437
+00:30:31,090 --> 00:30:34,950
+implantation وهذا الهدف الأساسي منها إنه يصير في
+
+438
+00:30:34,950 --> 00:30:38,010
+عندي direct contact ما بين الخلايا الخاصة بالـ
+
+439
+00:30:38,010 --> 00:30:41,930
+embryonic stem cell أو الـ embryonic cell و ال
+
+440
+00:30:41,930 --> 00:30:46,250
+endometrium of female الموجودة في بطانة الرحم مما
+
+441
+00:30:46,250 --> 00:30:49,810
+يحسن عملية الـ implantation الـ zona pellucida can be
+
+442
+00:30:49,810 --> 00:30:53,410
+totally removed by chemical or enzymatic method or
+
+443
+00:30:53,410 --> 00:30:58,900
+by using laser يعني أنا ممكن أعمل pores أو holes أو
+
+444
+00:30:58,900 --> 00:31:01,900
+completely removing أو partially removing الأربعة
+
+445
+00:31:01,900 --> 00:31:06,080
+بناء على حالة الـ zona pellucida من خلال طريقة
+
+446
+00:31:06,080 --> 00:31:10,420
+ميكانيكية طريقة كيميائية أو استخدام إنزيمات أو
+
+447
+00:31:10,420 --> 00:31:16,020
+باستخدام الـ laser طلاقات الـ laser هناخد أكثر من
+
+448
+00:31:16,020 --> 00:31:19,580
+طريقة جزء هناخده حاليًا و الجزء الثاني هناخده لما
+
+449
+00:31:19,580 --> 00:31:24,340
+نقول polar body biopsy أنواع من أنواع التخفيف أول
+
+450
+00:31:24,340 --> 00:31:28,660
+طريقة هي طريقة الـ traditional method وهي عمل
+
+451
+00:31:28,660 --> 00:31:32,600
+pores و holes في الـ zona pellucida من خلال الـ
+
+452
+00:31:32,600 --> 00:31:36,680
+mechanical zona pellucida dissection أو الـ
+
+453
+00:31:36,680 --> 00:31:41,120
+traditional method ببساطة جدا بجيب الطبق اللي فيه
+
+454
+00:31:41,120 --> 00:31:46,320
+الجنين بعد عملية تطوره وانقسامه بوضعه على stage
+
+455
+00:31:46,320 --> 00:31:51,380
+درجة حرارته 37 في منطقة معقمة بنسبة 100% تحت ال
+
+456
+00:31:51,380 --> 00:31:56,760
+inverted microscope بحمل الجنين وبثبته باستخدام ال
+
+457
+00:31:56,760 --> 00:31:59,740
+holder أو الـ sucker أو الـ suction holder أو ال
+
+458
+00:31:59,740 --> 00:32:04,320
+holding tube الموجودة دائما على جهة اليسار اللي
+
+459
+00:32:04,320 --> 00:32:06,920
+أنا كنت بثبت فيها البويضة أثناء عملية الـ injection
+
+460
+00:32:06,920 --> 00:32:11,620
+فكده أنا ثبتت الجنين وبجيب الـ injection needle
+
+461
+00:32:11,620 --> 00:32:17,540
+اللي كنت أحطّ فيها الـ sperm بعمل اختراق بعمل اختراق
+
+462
+00:32:17,540 --> 00:32:22,020
+للجنين في الغلاف الخارجي ببدأ من الساعة الواحدة و
+
+463
+00:32:22,020 --> 00:32:26,560
+بصل للساعة 11 الساعة الواحدة للساعة 11 شو يعني
+
+464
+00:32:26,560 --> 00:32:29,400
+الساعة الواحدة للساعة 11؟ لإن الجنين عبارة عن دائرة
+
+465
+00:32:29,400 --> 00:32:35,020
+بقسمها ساعات 12 6 3 9 أنا بدخلت بال
+
+466
+00:32:35,020 --> 00:32:39,300
+injection needle injection needle من الساعة الواحدة هطلع هتخرج
+
+467
+00:32:39,300 --> 00:32:42,680
+الـ needle من الساعة 11 بعد كده أعمل releasing لل
+
+468
+00:32:42,680 --> 00:32:49,720
+embryo بإني أخلي الـ holder tube الضغط فيها غير كافي
+
+469
+00:32:49,720 --> 00:32:52,140
+إنه يبدأ يعمل catching للـ embryo فالـ embryo
+
+470
+00:32:52,140 --> 00:32:56,980
+بيصير معلق في الـ injection needle باجي بعمل عملية
+
+471
+00:32:56,980 --> 00:33:02,800
+احتكاك بالـ needle في طرف الـ holder tube علشان أعمل
+
+472
+00:33:02,800 --> 00:33:08,240
+تآكل للـ zona pellucida فبهذا الشكل بكون عملت تآكل
+
+473
+00:33:08,240 --> 00:33:11,660
+لجزء من الـ zona pellucida وعملت removing أو
+
+474
+00:33:11,660 --> 00:33:15,260
+dissolving هدف نسميها طريقة التآكل أو الطريقة
+
+475
+00:33:15,260 --> 00:33:19,540
+الميكانيكية طريقة الاحتكاك التي تؤدي لتأكل الزونا
+
+476
+00:33:19,540 --> 00:33:23,720
+pellucida وهي طريقة ميكانيكية خلّينا نشوف بالفيديو
+
+477
+00:33:23,720 --> 00:33:27,460
+كيف تصير هذه الطريقة الميكانيكية اللي من خلالها
+
+478
+00:33:27,460 --> 00:33:31,800
+أنا بتخلص من جزء من الزونا pellucida وهي ال
+
+479
+00:33:31,800 --> 00:33:38,800
+traditional method طبعًا
+
+480
+00:33:38,800 --> 00:33:43,640
+هي عند البويضة عفوًا للجنين الجنين هذا عند الـ holder
+
+481
+00:33:43,640 --> 00:33:47,690
+أو الـ suction tube وهذه الـ injection needle أو في
+
+482
+00:33:47,690 --> 00:33:51,370
+بعض الأحيان بيسموها needle الخاصة بعملية
+
+483
+00:33:51,370 --> 00:33:59,730
+zona pellucida dissolving باجي بعمل fixation و بعمل
+
+484
+00:33:59,730 --> 00:34:04,730
+holding للـ embryo باستخدام الـ holder tube هي
+
+485
+00:34:04,730 --> 00:34:09,610
+الساعة 12 هي الساعة 6 هي الساعة 3 هي الساعة 9 باجي
+
+486
+00:34:09,610 --> 00:34:13,290
+بأخترق من الساعة 1 في هذا الاتجاه و بطلع بالـ needle
+
+487
+00:34:13,290 --> 00:34:17,280
+من الساعة 11 إن ما أضرب حوافّها في منطقة الزونا
+
+488
+00:34:17,280 --> 00:34:24,100
+pellucida الفاتحة دخل
+
+489
+00:34:24,100 --> 00:34:31,160
+بالـ needle المفروض يخرج من الطرف الآخر خرج
+
+490
+00:34:31,160 --> 00:34:34,340
+من الطرف الآخر ما بين الساعة الواحدة و 12 و خرج
+
+491
+00:34:34,340 --> 00:34:40,600
+ما بين الساعة 11 و 12 بعدين ببدأ يعمل
+
+492
+00:34:40,600 --> 00:34:49,460
+احتكاك بجزء السفلي للـ holder tube كده بيكون بدأ الجنين
+
+493
+00:34:49,460 --> 00:34:52,520
+يخرج زي ما احنا شايفين في هذه المنطقة هذه معناه
+
+494
+00:34:52,520 --> 00:34:56,940
+صار في عدة opening للجنين أو الخلايا الـ blastomeres
+
+495
+00:34:56,940 --> 00:35:00,380
+أو الـ blastocyst بدأت تنفذ للخارج
+
+496
+00:35:03,860 --> 00:35:09,020
+هذه الفكرة بتسميها الـ traditional method أو
+
+497
+00:35:09,020 --> 00:35:13,700
+mechanical method for assist hatching فقط لغة هذا
+
+498
+00:35:13,700 --> 00:35:19,360
+كثير الناس بتسويها و مازالت بتحقق نجاحات قوية طيب
+
+499
+00:35:19,360 --> 00:35:24,680
+طب أنا عملت hatching وعملت pores أو holes في
+
+500
+00:35:24,680 --> 00:35:27,280
+الـ zona pellucida هل ممكن أعملها قبل عملية ال
+
+501
+00:35:27,280 --> 00:35:32,330
+implantation اه ممكن أعملها طب شو هدفها؟ هدفها إن
+
+502
+00:35:32,330 --> 00:35:36,510
+أحصل على مادة وراثية خاصة بالجنين أو أحصل على مادة
+
+503
+00:35:36,510 --> 00:35:40,470
+وراثية خاصة بالأم من أجل الفحوصات الوراثية التي
+
+504
+00:35:40,470 --> 00:35:44,670
+تسمى pre-implantation genetic testing يعني الفحص
+
+505
+00:35:44,670 --> 00:35:49,370
+الجنيني أو الفحص الجيني قبل عملية الـ implantation
+
+506
+00:35:49,370 --> 00:35:54,430
+أو الانغراس أو الزراعة أو إعادة الـ embryo هذا
+
+507
+00:35:54,430 --> 00:35:58,270
+مصطلح بنسميه polar body biopsy ممكن آخذ polar body
+
+508
+00:35:58,270 --> 00:36:01,870
+biopsy يعني آخذ جزء من الـ polar body و أعمله
+
+509
+00:36:01,870 --> 00:36:05,510
+genetic testing فلازم عشان أصل للـ polar body أعمل
+
+510
+00:36:05,510 --> 00:36:08,150
+opening في الـ zona pellucida لأن أحنا عارفين أن
+
+511
+00:36:08,150 --> 00:36:11,670
+البويضة الملقحة فيها two polar body بتكون ما بين
+
+512
+00:36:11,670 --> 00:36:15,690
+البويضة و ما بين الـ zona pellucida فلازم أخترق ال
+
+513
+00:36:15,690 --> 00:36:18,910
+zona pellucida عشان أعمل suction للـ polar body تحت
+
+514
+00:36:18,910 --> 00:36:23,210
+مصطلح polar body biopsy الـ polar body biopsy كان
+
+515
+00:36:23,210 --> 00:36:28,150
+أول ما تم تكوينه و إنجازه في عام 1990 ال
+
+516
+00:36:28,150 --> 00:36:32,200
+polar body بيحتوي على المادة الوراثية الخاصة بالأم
+
+517
+00:36:32,200 --> 00:36:35,860
+polar body consists of genetic material related to
+
+518
+00:36:35,860 --> 00:36:39,720
+mother or maternal only خدوا بالكم من القصة يعني
+
+519
+00:36:39,720 --> 00:36:43,780
+أي مرض وراثي متعلق بالأم بأفحصه من خلال الـ polar
+
+520
+00:36:43,780 --> 00:36:48,780
+body أي مرض وراثي متعلق بالجنين بأفحصه من خلال ال
+
+521
+00:36:48,780 --> 00:36:50,260
+embryonic cell
+
+522
+00:36:54,000 --> 00:36:56,480
+The analysis polar body can be used to determine
+
+523
+00:36:56,480 --> 00:37:00,860
+chromosomal aneuploidy related to maternal meiosis
+
+524
+00:37:00,860 --> 00:37:05,180
+and maternal divide-unbalanced translocation
+
+525
+00:37:05,180 --> 00:37:10,320
+chromosome. To detect single gene defect related
+
+526
+00:37:10,320 --> 00:37:13,100
+to who related to the mother related to the
+
+527
+00:37:13,100 --> 00:37:19,100
+maternal allowing for day 3 embryo transfer ممكن
+
+528
+00:37:19,100 --> 00:37:23,980
+أنا أستخدم الـ polar body علشان أعمل HLA typing وهي
+
+529
+00:37:23,980 --> 00:37:27,840
+human leukocyte antigen typing وهو التوافق وممكن
+
+530
+00:37:27,840 --> 00:37:33,560
+أفحص من خلالها الـ X-linked disorder خاصة لما نقول X
+
+531
+00:37:33,560 --> 00:37:37,340
+linked disorder مفهوم أن معظم الأمراض الوراثية
+
+532
+00:37:37,340 --> 00:37:41,520
+المرتبطة بالـ X linked سواء كانت X-linked dominant أو X
+
+533
+00:37:41,520 --> 00:37:44,980
+linked recessive وعارفينها أن مصدر الخلل بيكون الأم
+
+534
+00:37:44,980 --> 00:37:51,240
+في هذه الحالة إيه الـ polar body؟ هي الـ GVBD طبعًا
+
+535
+00:37:51,240 --> 00:37:55,940
+هذه الـ spindle الـ simply بعدين صار عندي هجرة
+
+536
+00:37:55,940 --> 00:37:59,740
+جزء من الخلايا أو عفوًا جزء من الكروموسومات إلى
+
+537
+00:37:59,740 --> 00:38:03,280
+طرف الخلية والجزء الآخر تبقى توني الـ first
+
+538
+00:38:03,280 --> 00:38:06,760
+polar body بعد الـ fertilization أي النواة الذكرية
+
+539
+00:38:06,760 --> 00:38:10,560
+النواة الأنثوية اندمجت صار الـ fertilization خرج ال
+
+540
+00:38:10,560 --> 00:38:13,500
+second polar body فأنا ممكن أسحب هذا الـ polar body
+
+541
+00:38:13,500 --> 00:38:16,520
+و ممكن أسحب اثنين مع بعض هذا له وظيفة و هذا له
+
+542
+00:38:16,520 --> 00:38:22,100
+وظيفة هدف و أهداف و هدف طيب technical aspect of
+
+543
+00:38:22,100 --> 00:38:25,860
+polar body biopsy عرفنا أن الـ polar body مهم جدا
+
+544
+00:38:25,860 --> 00:38:29,960
+في تشخيص بعض الأمراض الوراثية الخاصة بالأم بعض
+
+545
+00:38:29,960 --> 00:38:32,120
+الأمراض المتعلقة بالـ abnormal chromosome
+
+546
+00:38:32,120 --> 00:38:36,980
+structural or number فبالتالي لازم أعمل opening في
+
+547
+00:38:36,980 --> 00:38:40,320
+الـ zona pellucida علشان أصل للـ polar body و أعمله
+
+548
+00:38:40,320 --> 00:38:44,610
+suction مهم جدا الـ time The most relevant part of
+
+549
+00:38:44,610 --> 00:38:47,750
+polar body biopsy are timing of biopsy, the
+
+550
+00:38:47,750 --> 00:38:50,050
+opening of zona pellucida, and the removing of
+
+551
+00:38:50,050 --> 00:38:53,470
+polar body يعني ثلاث مراحل متى أعمل polar body
+
+552
+00:38:53,470 --> 00:38:58,030
+biopsy و لماذا؟ كيف يمكن فتح الـ zona pellucida و
+
+553
+00:38:58,030 --> 00:39:01,450
+أعمل opening فيها؟ و كيف يتم إزالة الـ polar body؟
+
+554
+00:39:01,450 --> 00:39:05,830
+هذه الثلاث نقاط الأساسية والمهمة الـ timing and
+
+555
+00:39:05,830 --> 00:39:08,510
+oocyte representing a first polar body is
+
+556
+00:39:08,510 --> 00:39:12,150
+usually considered to be metaphase II يعني أي
+
+557
+00:39:12,150 --> 00:39:16,820
+بويضة يظهر فيها الـ First Polar Body هي بويضة ناضجة
+
+558
+00:39:16,820 --> 00:39:21,860
+وقفت في الـ Metaphase 2 يعني الـ Metaphase الخاص
+
+559
+00:39:21,860 --> 00:39:25,880
+بـ الأقسام الميوز الثاني وتكون صالحة لعملية الحقن
+
+560
+00:39:25,880 --> 00:39:29,580
+فبالتالي ممكن أحصل على الـ Polar Body منها الـ 
+
+561
+00:39:29,580 --> 00:39:32,160
+Zona pellucida ممكن أعملها Opening من خلال
+
+562
+00:39:32,160 --> 00:39:34,980
+Mechanical زي ما شوفنا قبل شوية الفيديو أو 
+
+563
+00:39:34,980 --> 00:39:38,180
+Chemical باستخدام انزيم معين هتتكلم عنه وLaser
+
+564
+00:39:38,180 --> 00:39:41,960
+Hatching Opening إنه أنا أستخدم الـ Laser  طلقات
+
+565
+00:39:41,960 --> 00:39:46,680
+الـ Laser  الـ chemical الـ mechanical أتكلمنا عنه
+
+566
+00:39:46,680 --> 00:39:50,080
+الـ chemical أنه أنا بستخدم solution بيسموه acidic
+
+567
+00:39:50,080 --> 00:39:56,060
+Tyrode's solution وهي أول طريقة تم فيها استخدام مادة
+
+568
+00:39:56,060 --> 00:39:59,760
+كيميائية من أجل إزالة جزء من الـ zona pellucida
+
+569
+00:39:59,760 --> 00:40:04,720
+وعمل zona pellucida opening هذي استخدموها بعد الـ
+
+570
+00:40:04,720 --> 00:40:09,440
+chemical الـ acidic Tyrode's كان بي applied at the
+
+571
+00:40:09,440 --> 00:40:12,870
+embryo stage Applied at the embryo stage, there was
+
+572
+00:40:12,870 --> 00:40:15,690
+an inhibitory effect in the embryonic development
+
+573
+00:40:15,690 --> 00:40:19,570
+when oocytes were exposed to the ascetic Tyrode's
+
+574
+00:40:19,570 --> 00:40:22,270
+يعني ال Tyrode's أو ال ascetic Tyrode's okay أنا ممكن
+
+575
+00:40:22,270 --> 00:40:25,990
+أستخدمه لعمل zona pellucida hatching ولكن ال side
+
+576
+00:40:25,990 --> 00:40:28,410
+effect ايه له أو ال disadvantage انه ممكن يعمل
+
+577
+00:40:28,410 --> 00:40:32,710
+inhibition لل embryo development وانا رأسمالي في
+
+578
+00:40:32,710 --> 00:40:36,930
+هذه الحتة ال embryo مش منطق اعمله inhibition لأنه
+
+579
+00:40:36,930 --> 00:40:40,480
+ممكن يعملي abnormality في الـ embryo development،
+
+580
+00:40:40,480 --> 00:40:42,500
+abnormality في الـ embryo development و أخسر
+
+581
+00:40:42,500 --> 00:40:47,300
+الجنين Therefore, since both oocytes and polar body
+
+582
+00:40:47,300 --> 00:40:50,180
+are sensitive to the effect of this acid, zona
+
+583
+00:40:50,180 --> 00:40:54,100
+peellucida draining by acidic Tyrode's solution is unsuitable for
+
+584
+00:40:54,100 --> 00:40:57,940
+polar body biopsy عشان كده أنا مهمنيش أعمل أو مش
+
+585
+00:40:57,940 --> 00:41:03,200
+لازم أعمل polar body biopsy أو zona pellucida
+
+586
+00:41:03,200 --> 00:41:06,800
+opening باستخدام ال chemical material اسمها Tyrode's
+
+587
+00:41:06,800 --> 00:41:10,300
+acid أو Tyrode's solution اللي هنا بتأثر شكلا سلبيا
+
+588
+00:41:10,300 --> 00:41:16,620
+بشكل سلبي على ال embryo وعلى ال oocyte وعلى ال
+
+589
+00:41:16,620 --> 00:41:21,320
+polar body ال laser hatching وهي الطريقة التالية
+
+590
+00:41:21,320 --> 00:41:25,060
+اللتي تستخدم ببساطة جدا ان انا في عندي مطلق لل
+
+591
+00:41:25,060 --> 00:41:29,440
+laser هنشوفها في الفيديو كمان شوية بيجي بيعمل
+
+592
+00:41:29,440 --> 00:41:34,820
+طلقات لل laser في depth معين ب thickness معين بعدد
+
+593
+00:41:34,820 --> 00:41:39,320
+معين كأنه بيعمل thinning وتقشير للـ zona pellucida
+
+594
+00:41:39,320 --> 00:41:44,860
+ببساطة جدا طبعا ال laser assisted polar body biopsy
+
+595
+00:41:44,860 --> 00:41:48,240
+is the best method when the oocyte is fixed with
+
+596
+00:41:48,240 --> 00:41:51,180
+the holder capillary يعني بداية زي ما شوفنا في
+
+597
+00:41:51,180 --> 00:41:54,960
+الفيديو بعمل laser hatching إما بعملها للإمبريو أو
+
+598
+00:41:54,960 --> 00:41:58,740
+بعملها للبويضة وطالما أنا بتعمل polar body biopsy
+
+599
+00:41:58,740 --> 00:42:03,520
+إذا بعملها للبويضة الغير ملقحة أو الملقحة بناء على
+
+600
+00:42:03,520 --> 00:42:07,980
+أنا شو ايه بتشتغل والأفضل أعملها للملقحة بعد
+
+601
+00:42:07,980 --> 00:42:11,680
+تكوين وظهور ال tube polar body ال first وال second
+
+602
+00:42:11,680 --> 00:42:17,120
+بعمل fixation ل ... أو بعمل حاجة بنسميها fixation ل
+
+603
+00:42:17,120 --> 00:42:22,580
+... أو catching ل ال oocyte باستخدام ال holder tube
+
+604
+00:42:22,580 --> 00:42:26,920
+بعدين باجي بشعاع ال laser بحدد عند الساعة 12 لساعة
+
+605
+00:42:26,920 --> 00:42:31,080
+3 مناطق الطلاقات اللي هيطلق عليها ال laser ب depth
+
+606
+00:42:31,080 --> 00:42:37,000
+معين كأنه بعملي تقشير للـ zona pellucida هنشوفها
+
+607
+00:42:37,000 --> 00:42:40,820
+بالفيديو ال opening تقريبا بتكون ال size تبعها من
+
+608
+00:42:40,820 --> 00:42:44,520
+15 إلى 25 ميكرو متر وبتكون ما بين الساعة الثانية
+
+609
+00:42:44,520 --> 00:42:47,100
+والساعة الثالثة الساعة الثانية والساعة الثالثة
+
+610
+00:42:47,100 --> 00:42:53,120
+طبعا بيصير عندي thinning لل zona pellucida and by
+
+611
+00:42:53,120 --> 00:42:57,280
+pushing the biopsy capillary into the perivitelline space
+
+612
+00:42:57,280 --> 00:43:02,280
+both polar bodies can be removed together يعني بمعنى
+
+613
+00:43:02,280 --> 00:43:08,640
+آخر بعد أن أنا معملت holding و fixation ل ال .. ال
+
+614
+00:43:08,640 --> 00:43:13,080
+oocyte باستخدام ال .. ال holder tube و أعرضت طلقات
+
+615
+00:43:13,080 --> 00:43:15,600
+ال laser للمنطقة اتنين و تلاتة فصار في عندي فتحة
+
+616
+00:43:15,600 --> 00:43:18,260
+في المنطقة ما بين الساعة اتنين و تلاتة باجي ال
+
+617
+00:43:18,260 --> 00:43:22,380
+aspiration tube بدخل من خلال الفتحة و بعمل suction
+
+618
+00:43:22,380 --> 00:43:25,960
+لل polar body ممكن أعمل لل polar body الأول ممكن
+
+619
+00:43:25,960 --> 00:43:29,160
+أعمل لل polar body التاني كل واحد على حد أو ممكن
+
+620
+00:43:29,160 --> 00:43:35,420
+أعملهم مع بعض طبعا أعمل .. بقول في trick فني انه
+
+621
+00:43:35,420 --> 00:43:41,900
+بقول لي ببساطة وانت داخل ال aspiration tube عملت
+
+622
+00:43:41,900 --> 00:43:46,240
+catching لل first polar body حاول ارجع جدّام شوية وبعدين
+
+623
+00:43:46,240 --> 00:43:49,920
+بعدين اعمل aspiration لأن عملية التقديم بتحرك ال
+
+624
+00:43:49,920 --> 00:43:52,740
+first polar body لان عارفين احنا ال first polar
+
+625
+00:43:52,740 --> 00:43:55,880
+body بيكون في الأول يلي من جهة اليسار ال second
+
+626
+00:43:55,880 --> 00:43:58,720
+polar body يعني انت كأنك بتطلع في الأول ال second
+
+627
+00:43:58,720 --> 00:44:02,820
+polar body بعدين بتطلع ال first polar body لما تعمل
+
+628
+00:44:02,820 --> 00:44:06,100
+catching للـ second polar body اعمل عملية
+
+629
+00:44:06,100 --> 00:44:11,420
+إدخال ل ال aspiration tube بزيادة شوية عشان يتحرك
+
+630
+00:44:11,420 --> 00:44:16,560
+ال first polar body من مكانه ويصير سهل الحركة من
+
+631
+00:44:16,560 --> 00:44:21,080
+أجل تثير عملية ال suction الخاصة فيه The procedure
+
+632
+00:44:21,080 --> 00:44:26,240
+is accurate, reproducible and safe and it also
+
+633
+00:44:26,240 --> 00:44:28,360
+reduces the number of cells which cannot be
+
+634
+00:44:28,360 --> 00:44:32,080
+diagnosed as a result of a technical problem 
+
+635
+00:44:32,080 --> 00:44:35,840
+during biopsy procedure يعني مهم جدا بيقولك هذا
+
+636
+00:44:35,840 --> 00:44:40,560
+الطريقة طريقة ال laser hatching طريقة سهلة آمنة
+
+637
+00:44:40,560 --> 00:44:45,920
+مضمونة إلى حد ما تقلل عدد الخلايا التي تخرج من ال
+
+638
+00:44:45,920 --> 00:44:51,110
+embryo أو البويضة خلايا ال Polar Body Biopsy والتي
+
+639
+00:44:51,110 --> 00:44:56,350
+قد لا تساهم في عملية التشخيص الجيني طبعا هذه
+
+640
+00:44:56,350 --> 00:45:01,250
+الفكرة ببساطة هذه البويضة عند ال first polar body
+
+641
+00:45:01,250 --> 00:45:04,630
+موجود في ال aspiration needle وعند ال second
+
+642
+00:45:04,630 --> 00:45:08,650
+polar body وهذا ال first polar body لأن دائما هذه
+
+643
+00:45:08,650 --> 00:45:11,430
+البويضة يكون ال first polar body عند الساعة 12
+
+644
+00:45:11,430 --> 00:45:15,910
+for example وال second polar body على يمينه دائما
+
+645
+00:45:15,910 --> 00:45:19,130
+بيكون على يمينه فبالتالي لما انت تعمل دخول بال
+
+646
+00:45:19,130 --> 00:45:22,970
+aspiration needle أو aspiration pipet هتسحب في
+
+647
+00:45:22,970 --> 00:45:25,450
+البداية ال first polar body .. ال second polar
+
+648
+00:45:25,450 --> 00:45:29,980
+body ولكن في البداية هيكون ال second polar body هنا
+
+649
+00:45:29,980 --> 00:45:33,660
+هتدخل بال aspiration tube شوية فبالتالي بتكون حركة
+
+650
+00:45:33,660 --> 00:45:38,340
+ال polar body هذا عن مكانه فبتسحب ال second polar
+
+651
+00:45:38,340 --> 00:45:41,800
+body بتدخله داخل ال aspiration tube وبعدين بتسحب
+
+652
+00:45:41,800 --> 00:45:45,080
+ال second polar body كما هو ال first وال second
+
+653
+00:45:45,080 --> 00:45:49,200
+بيكون سحتهم مع بعض خليني أشوف الفيديو اللي بتكلم
+
+654
+00:45:49,200 --> 00:45:53,280
+عن هذه العملية وبعدين نرجع للموضوع مرة أخرى
+
+655
+00:46:00,380 --> 00:46:03,620
+طبعا هنا هيتكلم عن ال assist hatching باستخدام ال
+
+656
+00:46:03,620 --> 00:46:07,520
+laser طبعا يحدد المناطق هيما بين الساعة 2 والساعة
+
+657
+00:46:07,520 --> 00:46:11,600
+3 هيعمل اطلاق لشعاع ال laser في المناطق هذه
+
+658
+00:46:19,130 --> 00:46:22,930
+هو عنده زي حاجة تشبه القناص إلى حد ما زي شريط
+
+659
+00:46:22,930 --> 00:46:26,270
+القناص بتغطي في هذه المنطقة تشوف حدد ال depth لوين
+
+660
+00:46:26,270 --> 00:46:31,250
+نهايته هذه حدد وبعمل clicking على الذر كأنه بطلق
+
+661
+00:46:31,250 --> 00:46:35,410
+لل laser هنا بيكون حدد المكان مجرد ما ضغط على الذر
+
+662
+00:46:35,410 --> 00:46:39,030
+بيصير اطلاق لشعاع ال laser بيكون معايره ل depth
+
+663
+00:46:39,030 --> 00:46:43,370
+معين بقوة معينة هذي ال Embryonic stem cell في
+
+664
+00:46:43,370 --> 00:46:43,730
+الغالب
+
+665
+00:47:07,290 --> 00:47:10,870
+شوفش هنا كتب start firing لما ضغط على الذر هذا
+
+666
+00:47:10,870 --> 00:47:15,470
+الذر ده اسمها start firing يعني بداية إطلاق ال
+
+667
+00:47:15,470 --> 00:47:18,410
+laser فبطلقها ب depth معين في مكان معين بناء على
+
+668
+00:47:18,410 --> 00:47:23,540
+المنطقة اللي حدث أيضا هنا بيقول يا كام holes بده
+
+669
+00:47:23,540 --> 00:47:26,720
+بده ال width بده ال size ده ال hole و كام hole بده
+
+670
+00:47:26,720 --> 00:47:29,720
+ستة سبعة تمانية بناء على حجم الخلية اللي بده
+
+671
+00:47:29,720 --> 00:47:34,080
+يسحبها طبعا هنا بده يسحب ال embryo cells احنا
+
+672
+00:47:34,080 --> 00:47:36,560
+بنحكي على ال biopsy بنفس الطريقة ولكن هنا بده يسحب
+
+673
+00:47:36,560 --> 00:47:39,700
+ال embryo cells فبالتالي بيكون أعمق علشان يصل ال
+
+674
+00:47:39,700 --> 00:47:40,940
+embryo بشكل أسلوب
+
+675
+00:48:08,590 --> 00:48:12,370
+هكذا بيكون عمل assist hatching باستخدام ال laser
+
+676
+00:48:12,370 --> 00:48:17,350
+أخرج embryonic stem cell واحدة طبعا ال polar body
+
+677
+00:48:17,350 --> 00:48:20,910
+مهم جدا مهم جدا ال polar body علشان يكشف على
+
+678
+00:48:20,910 --> 00:48:24,110
+الأمراض الوراثية المتعلقة بال female بشكل أساسي
+
+679
+00:48:38,850 --> 00:48:42,930
+هذا بيقلل كمية ال contamination التي يمكن أن تحدث
+
+680
+00:48:42,930 --> 00:48:46,990
+فبالتالي من خلال تقليل عدد الخلايا التي يمكن أن
+
+681
+00:48:46,990 --> 00:48:51,890
+تخرج مع ال polar body مع ال polar body هذا شكل أخر
+
+682
+00:48:51,890 --> 00:48:56,830
+من الأشكال الخاصة فيه طبعا هذه بدخل ب aspiration
+
+683
+00:48:56,830 --> 00:49:01,490
+needle سحب أو ثبت ال first polar body بعدين
+
+684
+00:49:01,490 --> 00:49:04,890
+بيسحبوا بهذا الشكل سحب ال second polar body بعدين
+
+685
+00:49:04,890 --> 00:49:08,570
+سحب ال first polar body طلع منهم وأضافهم في منطقة
+
+686
+00:49:08,960 --> 00:49:13,240
+خالية كدا سنكتفي بهذا القدر في هذه المحاضرة على
+
+687
+00:49:13,240 --> 00:49:16,640
+أمل أن نلتقي في محاضرة قادمة إن شاء الله
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Vk4A33MkSlQ_postprocess.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Vk4A33MkSlQ_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..26880fa511ff51fe1ed5f882e58b6f0da40f94a8
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Vk4A33MkSlQ_postprocess.srt
@@ -0,0 +1,2748 @@
+1
+00:00:00,670 --> 00:00:04,590
+بسم الله الرحمن الرحيم والصلاة والسلام على أفضل
+
+2
+00:00:04,590 --> 00:00:09,750
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا
+
+3
+00:00:09,750 --> 00:00:14,110
+الأعزاء أرجو من الله الكريم أن تكونوا جميعا بخير
+
+4
+00:00:14,110 --> 00:00:19,430
+وبصحة جيدة تكلمنا في المحاضرات السابقة عن أمور شتة
+
+5
+00:00:19,430 --> 00:00:25,430
+تتعلق بقضية التلقيح وعملية الحقن المجهري ومن أشهر
+
+6
+00:00:25,430 --> 00:00:29,820
+هذه المواضيع التي تحدثنا عنهاكيف تتكون الجميطات
+
+7
+00:00:29,820 --> 00:00:33,980
+عند ال male و ال female تحت عنوان spermatogenesis
+
+8
+00:00:33,980 --> 00:00:39,460
+و oogenesis كيف تنتقل هذه الجميطات من مكان التصنيع
+
+9
+00:00:39,460 --> 00:00:44,800
+إلى مكان التخزين ثم إلى مكان التطور والنضوج لكي
+
+10
+00:00:44,800 --> 00:00:49,500
+يمكن أن تستخدم ثم تحدثنا عن القالية التي يتم من
+
+11
+00:00:49,500 --> 00:00:53,240
+خلالها تحضير الأطواق الأطباق الخاصة بالحقن المجهري
+
+12
+00:00:53,240 --> 00:00:58,200
+تحت عنوان XY dish preparationثم تحدثنا عن عملية
+
+13
+00:00:58,200 --> 00:01:02,620
+الحقن المجهري وكيف تتم ومن خلال عملية التحدث عن
+
+14
+00:01:02,620 --> 00:01:05,760
+الحقن المجهري تحدثنا عن آلية التعامل مع ال
+
+15
+00:01:05,760 --> 00:01:09,060
+spermatozoa من خلال مصطلح سمناه sperm
+
+16
+00:01:09,060 --> 00:01:14,240
+immobilization spermatozoa ثم تحدثنا عن ال oocyte
+
+17
+00:01:14,240 --> 00:01:19,040
+preparation من خلال عملية ال denudationوهي عبارة
+
+18
+00:01:19,040 --> 00:01:23,720
+عن التخلص من الخلايا الذائدة المحيطة بالبويضات
+
+19
+00:01:23,720 --> 00:01:29,080
+الناضجة التي تصلح لعملية الحقن الآن تمت عملية
+
+20
+00:01:29,080 --> 00:01:34,320
+الحقن سوف نتحدث عن عدة أمور مختلفة لها بالعلاقة
+
+21
+00:01:34,320 --> 00:01:39,080
+بانقسام الخلايا الملقحة أو البويضات الملقحة وكيف
+
+22
+00:01:39,080 --> 00:01:43,420
+تنقسم هذه البويضات وماذا تسمى كل مرحلة من مراحل
+
+23
+00:01:43,420 --> 00:01:48,460
+الانقسام ثم كيف تنتقل البويضة الملقحةمن مكان
+
+24
+00:01:48,460 --> 00:01:52,220
+التلقيح الطبيعي وهو عبارة عن الـ Fallopian tube
+
+25
+00:01:52,220 --> 00:01:58,040
+حتى حدوث عملية implantation في بطانة الرحمة هذا ما
+
+26
+00:01:58,040 --> 00:02:02,440
+سوف نتحدث عنه في هذا الشيء من هذه المحاضرة ثم
+
+27
+00:02:02,440 --> 00:02:07,280
+ننتقل إلى موضوع جديد وهو كيف نحدد بعض الأمراض
+
+28
+00:02:07,280 --> 00:02:11,580
+الوراثية المتعلقة بالأجنة من خلال ما يُعرف اسم
+
+29
+00:02:11,580 --> 00:02:18,850
+Empyreobiosis أو polar body biopsyهذا ما سوف نتحدث
+
+30
+00:02:18,850 --> 00:02:23,670
+عنه في الـ Chapter رقم 6 After fertilization، بعد
+
+31
+00:02:23,670 --> 00:02:27,090
+عملية ال fertilization وهو إدخال single sperm في
+
+32
+00:02:27,090 --> 00:02:31,470
+mature oocyte تبدأ عملية اندماج النواذ ذكرية مع
+
+33
+00:02:31,470 --> 00:02:35,530
+النواذ أنثوية، مما يؤدي إلى تكوين خلية جديدة تسمى
+
+34
+00:02:35,530 --> 00:02:41,450
+الزيجوت فالزيجوت هي عبارة عن أول ناتج طبيعي لعملية
+
+35
+00:02:41,450 --> 00:02:45,840
+الحقن المجهريإلى العملية تكوين الزيجوت بيحدث
+
+36
+00:02:45,840 --> 00:02:50,360
+shifting لـmetabolic process و ال event اللي ممكن
+
+37
+00:02:50,360 --> 00:02:55,080
+تحدث في الخلية والبوايضة الملقحة مما يؤدي إلى
+
+38
+00:02:55,080 --> 00:03:00,060
+دخولها في عدة انقسامات للحصول على ال embryo الذي
+
+39
+00:03:00,060 --> 00:03:04,620
+سوف يحدث له عملية implantation في بطانة الرحم
+
+40
+00:03:04,620 --> 00:03:10,290
+ليكوّن a new babyخلال هذه الفترة وخلال هذه العملية
+
+41
+00:03:10,290 --> 00:03:14,730
+من لحظة التلقيح وتكون الـ Zygote حتى لحظة ال
+
+42
+00:03:14,730 --> 00:03:18,410
+implantation يبقى الجنين أو قبل لحظة ال
+
+43
+00:03:18,410 --> 00:03:22,270
+implantation بشيء بسيط يبقى الجنين والخلايا
+
+44
+00:03:22,270 --> 00:03:26,190
+الجنينية محاطة بغلاف واحد وهو عبارة عن الـ
+
+45
+00:03:26,190 --> 00:03:31,410
+Zoonopelucida و لا يتحطم هذا الغلاف يعني ما بيصير
+
+46
+00:03:31,410 --> 00:03:35,210
+the structure أو breakdown for Zoonopelucida حتى
+
+47
+00:03:35,210 --> 00:03:39,630
+لحظة ال implantationبمجرد أن يصل الجنين لعدد معين
+
+48
+00:03:39,630 --> 00:03:44,310
+من القسمات و الخلايا و يصل للمكان المعدله لكي يحدث
+
+49
+00:03:44,310 --> 00:03:47,270
+له عملية انغراض في بطانة الرحل تبدأ الـ
+
+50
+00:03:47,270 --> 00:03:50,670
+Zoonopelucida في التهتق و تبدأ الـ Zoonopelucida
+
+51
+00:03:50,670 --> 00:03:55,910
+في التكسر و التحطم لكي تسمح بوجود منفذ لهذا الجنين
+
+52
+00:03:55,910 --> 00:04:00,930
+لحدوث اتصال مباشر ما بينه و ما بين بطانة الرحل
+
+53
+00:04:00,930 --> 00:04:04,170
+الموجودة في المنطقة التي يحدث لها عملية ال
+
+54
+00:04:04,170 --> 00:04:10,040
+implantationالى حد ما حوالي 6 ايام بعد ذلك
+
+55
+00:04:10,040 --> 00:04:15,380
+الانبريو شد ذونا باليوسيدا واتشت اليوتران لين يعني
+
+56
+00:04:15,380 --> 00:04:20,060
+بعد ست أيام من عملية الحقل او بعد ست أيام بالضبط
+
+57
+00:04:20,060 --> 00:04:26,860
+يبدأ الانبريو بالخروج من الذونا باليوسيدا الاتفاق
+
+58
+00:04:26,860 --> 00:04:31,140
+بين البلاسنتل والماترة التي أدت لإنقاذ الوحوسيت
+
+59
+00:04:31,140 --> 00:04:35,400
+لتخزين كمية يوكساكthat needed during development
+
+60
+00:04:35,400 --> 00:04:39,440
+therefore the eggs of mammalian are very small هذه
+
+61
+00:04:39,440 --> 00:04:44,920
+الفقرة بتوضع سؤال مهم جدا لو أنا قرنت البوايضة
+
+62
+00:04:44,920 --> 00:04:49,300
+الخاصة بالفديات زي ال human مع البوايضة الخاصة بال
+
+63
+00:04:49,300 --> 00:04:54,180
+animal بالطيور مثلا في بعض الحيوانات بتبيض على
+
+64
+00:04:54,180 --> 00:05:00,260
+سبيل المثال فيه فبالتالي لو أنا قرنت حجم البوايضة
+
+65
+00:05:00,260 --> 00:05:04,270
+مع حجم البوايضة الأخرىهلاجي حجم البوايضة الخاصة
+
+66
+00:05:04,270 --> 00:05:08,190
+بليه human صغيرة جدا مقارنة مع حجم البوايضة الخاصة
+
+67
+00:05:08,190 --> 00:05:14,490
+ببعض أنواع من الطيور أو بعض أنواع من الحيوانات
+
+68
+00:05:14,490 --> 00:05:19,150
+التي الطبيب فالسبب في هذا الموضوع يرجع إلى وجود
+
+69
+00:05:19,150 --> 00:05:23,310
+كمية كبيرة جدا من ال yolk sac في عفوا كمية كبيرة
+
+70
+00:05:23,310 --> 00:05:28,750
+جدا من ال yolk داخل ال yolk sac تستخدمها البوايضة
+
+71
+00:05:28,750 --> 00:05:34,160
+ذات الحجم الكبير لعملية التخذيةوالنموك للحصول على
+
+72
+00:05:34,160 --> 00:05:38,140
+جنين طبيعي وجنين كامل النمو بينما في ال human
+
+73
+00:05:38,140 --> 00:05:43,220
+البوايضة الملقحة تتحول إلى embryo ال embryo ينغمس
+
+74
+00:05:43,220 --> 00:05:47,100
+في بطانة الرحم الخاصة بالأم مما يسمح له بتكوين
+
+75
+00:05:47,100 --> 00:05:51,360
+structure بنسميه placenta التي تصبح فيما بعد مصدر
+
+76
+00:05:51,360 --> 00:05:55,680
+للغذاء مصدر للغذاء فلا داعي ولا حاجة للبوايضة
+
+77
+00:05:55,680 --> 00:05:59,880
+الخاصة بال human ان تتغذى و تتخزن تتغذى نفسه بنفسه
+
+78
+00:05:59,880 --> 00:06:04,220
+او تتخزن كمية كبيرة جدامن اليوك في داخلها فبالتالي
+
+79
+00:06:04,220 --> 00:06:09,360
+الحجم يبقى صغير إذا كبر الحجم من صغره يعتمد على هل
+
+80
+00:06:09,360 --> 00:06:12,960
+البويضة بعد الطلقية سوف تغذي نفسها من نفسها أو
+
+81
+00:06:12,960 --> 00:06:16,160
+تعتمد على مصدر آخر إذا تغذي نفسها من نفسها زي
+
+82
+00:06:16,160 --> 00:06:21,400
+البويضات بتاعة القيور مثلا فبالتالي لازم تكون كمية
+
+83
+00:06:21,400 --> 00:06:25,580
+كبيرة جدا من اليوك مخزنة بداخل البويضة حتى تسمح
+
+84
+00:06:25,580 --> 00:06:30,160
+لها بعملية النمو والانقسامMammalian cleavage is a
+
+85
+00:06:30,160 --> 00:06:34,900
+prolonged process that typically takes a large
+
+86
+00:06:34,900 --> 00:06:39,680
+amount of time and requires to transport the early
+
+87
+00:06:39,680 --> 00:06:44,340
+embryo form its site of fertilization to the site
+
+88
+00:06:44,340 --> 00:06:48,320
+of implantation بمعنى آخر أن عملية الـ cleavage
+
+89
+00:06:48,320 --> 00:06:51,740
+الخاصة بالبويضة الملقح الخاصة بالماماليا الفديات
+
+90
+00:06:51,740 --> 00:06:55,160
+تأخذ فترة زمنية طويلة جدا ما بين لحظة ال
+
+91
+00:06:55,160 --> 00:06:59,980
+fertilizationمرورا بالانقسامات المتتالية ووصولا
+
+92
+00:06:59,980 --> 00:07:03,900
+إلى منطقة الـ Implantation في بيطانة الرحم الحنعرف
+
+93
+00:07:03,900 --> 00:07:07,720
+جديش بتاخد فترة زمنية ال development procedure at
+
+94
+00:07:07,720 --> 00:07:11,280
+the rate of roughly one cleavage division per one
+
+95
+00:07:11,280 --> 00:07:15,500
+day يعني عملية الانقسام في البوايدة الملقحة في أول
+
+96
+00:07:15,500 --> 00:07:19,400
+يومين بيكون ثابت انقسام واحد كل يومبعد كده بعد
+
+97
+00:07:19,400 --> 00:07:22,880
+اليوم الأول والتاني بشكل أساسي تختلف معدّى
+
+98
+00:07:22,880 --> 00:07:27,180
+الإنقسامات فتصبح متسارعة عشان تصل للعدد المطموعة
+
+99
+00:07:27,180 --> 00:07:33,620
+من الخلايا بعد اليوم التاني أو بعد ما تكوين two
+
+100
+00:07:33,620 --> 00:07:37,500
+cells خلينا نسميها بشكل أوضح وشكل أدق بيصير في
+
+101
+00:07:37,500 --> 00:07:40,960
+عندي نوع من أنواع التزامن في الإنقسامات بمعنى أخر
+
+102
+00:07:40,960 --> 00:07:44,160
+أن الخلية في اليوم الأول بتاعة خليتين فبسمّي
+
+103
+00:07:44,160 --> 00:07:49,540
+الخليتينالـ Plastomere بعد كده الـ Plastomere
+
+104
+00:07:49,540 --> 00:07:54,360
+هتنقسم إلى تلات خلائي والتلات و كذا هينقسموا يعني
+
+105
+00:07:54,360 --> 00:07:56,560
+بيصير عندى اتنين الاتنين بيصيروا تلاتة بعدين
+
+106
+00:07:56,560 --> 00:07:58,740
+بيصيروا اربعة الاربعة بيصيروا تمانية تمانية
+
+107
+00:07:58,740 --> 00:08:02,840
+بيصيروا ستاشر لما نتصل لمرحلة خلية واحدة تحتوي
+
+108
+00:08:02,840 --> 00:08:07,400
+بداخلها على ست عشر خلية بنسمي ال whole structure
+
+109
+00:08:07,400 --> 00:08:11,560
+موريلا بنسمي ال whole structure موريلا وهذا الكلام
+
+110
+00:08:11,560 --> 00:08:16,320
+خدناه في المحاضرة السابقةالخلايا الموجودة بداخل
+
+111
+00:08:16,320 --> 00:08:20,000
+الخلية الأم أو البويضة الأم إذا كانت تحتوي على
+
+112
+00:08:20,000 --> 00:08:24,540
+تمانية لستة عشر stage the embryo of placental
+
+113
+00:08:24,540 --> 00:08:27,360
+mammalian enter in the phase called competition
+
+114
+00:08:27,360 --> 00:08:31,920
+يعني بمجرد ما تصل عدد الخلايا في الداخل اللي
+
+115
+00:08:31,920 --> 00:08:36,860
+سمناها embryonic stem cell تمان خلايا وتبدأ تتزايد
+
+116
+00:08:36,860 --> 00:08:40,670
+لتصل إلى ستة عشر خلية عشان تعطين الموريلابصير هذه
+
+117
+00:08:40,670 --> 00:08:43,570
+المرحلة بنسميها competition stage شو معنى
+
+118
+00:08:43,570 --> 00:08:45,450
+competition stage؟ what's the meaning of
+
+119
+00:08:45,450 --> 00:08:47,690
+competition stage؟ what do you know about the
+
+120
+00:08:47,690 --> 00:08:50,730
+competition stage؟ ال competition stage ببساطة جدا
+
+121
+00:08:50,730 --> 00:08:54,150
+هي مرحلة يتم فيها تداخل الخلايا مع بعض على بعض
+
+122
+00:08:54,150 --> 00:08:59,930
+لدرجة انك مابتقدر تشوف حد كل خلية عن الأخرى انت
+
+123
+00:08:59,930 --> 00:09:04,650
+بتلاقيهم كجملة واحدة كتلة واحدة مدمجين مع بعض ومع
+
+124
+00:09:04,650 --> 00:09:09,490
+بعض مافيحدود ما بين الخلايا مافي خلية تقول والله
+
+125
+00:09:09,490 --> 00:09:13,770
+أنا هذا ال outer layer الخاص بيها بتلاقيهم نوع من
+
+126
+00:09:13,770 --> 00:09:17,470
+أنواع الاندماج this process which occur
+
+127
+00:09:17,470 --> 00:09:21,250
+approximately four days after fertilization وهذه
+
+128
+00:09:21,250 --> 00:09:26,590
+العملية بنسميها cavitation في عملية ال competition
+
+129
+00:09:26,590 --> 00:09:31,980
+بشكل أساسي بيصير اندماج الخلايا مع بعضها البعضمافي
+
+130
+00:09:31,980 --> 00:09:36,260
+عندى outer layer للخلايا وحدود الخلايا بتصير عندى
+
+131
+00:09:36,260 --> 00:09:39,840
+junction بين بعض البعض تحت مصطلح tied adhere
+
+132
+00:09:39,840 --> 00:09:44,180
+through the gap and tied junction and lose their
+
+133
+00:09:44,180 --> 00:09:48,820
+individual identity individual line win view from
+
+134
+00:09:48,820 --> 00:09:51,480
+the surface يعني الخلايا بتندمش مع بعض البعض
+
+135
+00:09:51,480 --> 00:09:55,640
+الخلايا تداخل مع بعض البعض مافي outer layer أو
+
+136
+00:09:55,640 --> 00:10:00,100
+outline لكل خلية مافي border لكل خليةبتلاقي
+
+137
+00:10:00,100 --> 00:10:03,300
+الخلايا اندمجت مع بعض البعض واتصلت مع بعض البعض
+
+138
+00:10:03,300 --> 00:10:08,680
+طبعا اندماج الخلايا وانغماسها مع بعض البعض المرحلة
+
+139
+00:10:08,680 --> 00:10:13,000
+كلها بنسميها competition as phase بينما ال process
+
+140
+00:10:13,000 --> 00:10:18,900
+هذه بنسميها cavitation وبتصير في اليوم الرابعمن
+
+141
+00:10:18,900 --> 00:10:22,480
+بعد عملية ال fertilization at this stage المقصود
+
+142
+00:10:22,480 --> 00:10:26,580
+فيه ال competition stage the embryo as whole is no
+
+143
+00:10:26,580 --> 00:10:30,720
+plastocyst لما بعد يصير عندي أربع أيام و يصير
+
+144
+00:10:30,720 --> 00:10:34,380
+الاندماج المتميز بين الخلايا يعني تصير مرحلة ال
+
+145
+00:10:34,380 --> 00:10:40,520
+cavitation بسمي ال structure ككل بسميه plastocyst
+
+146
+00:10:40,520 --> 00:10:45,500
+بسميه plastocyst خلاية أو صورة بتوضح الكلام هذا في
+
+147
+00:10:45,500 --> 00:10:49,890
+عندي هناوهي عبارة عن بويضة لقحت أعطتني في اليوم
+
+148
+00:10:49,890 --> 00:10:53,950
+الأول خليتين كانت one cells سميتها as I got بعدين
+
+149
+00:10:53,950 --> 00:10:56,870
+اتقسمت التلت ل two cells هذا في اليوم الأول في
+
+150
+00:10:56,870 --> 00:10:59,730
+اليوم التاني أدتني أربع خلايا كل خلية بتسميها plus
+
+151
+00:10:59,730 --> 00:11:04,110
+to minus في اليوم التاني ونص جريبا علشان نتصل
+
+152
+00:11:04,110 --> 00:11:08,030
+اليوم التالت وهي 8 من 8 ل 16 خلية في اليوم التالت
+
+153
+00:11:08,030 --> 00:11:12,410
+16 خلية اللي بتسميها morela في اليوم الرابع تصير
+
+154
+00:11:12,410 --> 00:11:17,240
+58 خلية بتسميها plus to sixthفي اليوم الخامس
+
+155
+00:11:17,240 --> 00:11:21,820
+بتنقسم إلى 107 خلية بنسميها Plastocyst أيضًا إذا
+
+156
+00:11:21,820 --> 00:11:27,280
+الموريلا بتظهر في اليوم التالت من الخسام وتحتوي
+
+157
+00:11:27,280 --> 00:11:32,940
+على أكتر من 8 خلايا كحد أدنى وحد أقصى 16 خلية
+
+158
+00:11:32,940 --> 00:11:37,640
+Plastocyst بتزيد عن 16 خلية وكل هذه المراحل بتكون
+
+159
+00:11:37,640 --> 00:11:40,700
+مازالت محاطة بالـ Zoonapelucida
+
+160
+00:11:42,660 --> 00:11:45,860
+At the beginning of cleavage, the zona is still in
+
+161
+00:11:45,860 --> 00:11:52,300
+case or in covering the
+
+162
+00:11:52,300 --> 00:11:56,120
+cell plus الـ cell المقصود فيها الخلايا الداخلية
+
+163
+00:11:56,120 --> 00:11:58,760
+ال embryonic stem cell يعني ال embryonic stem cell
+
+164
+00:11:58,760 --> 00:12:01,420
+ما ذالت ضمن محفظة واحدة اللي هي ال zona pellucida
+
+165
+00:12:01,420 --> 00:12:04,740
+و في الخارج يحيط بيها طبقة رقيقة من ال corona
+
+166
+00:12:04,740 --> 00:12:08,920
+radiata ال corona radiata تبقى كما هي حتى اليوم
+
+167
+00:12:08,920 --> 00:12:12,670
+الثانيبعد اليوم الثاني من عملية الإنقسامات تبدأ
+
+168
+00:12:12,670 --> 00:12:17,970
+بالاختفاء تدريجي رغم إن ال Corona Radiata منها
+
+169
+00:12:17,970 --> 00:12:21,310
+removing بالـdenodation ولكن ما بنقدر نعمل
+
+170
+00:12:21,310 --> 00:12:24,530
+removing completely بلقى جزء منها ما زال موجود
+
+171
+00:12:24,530 --> 00:12:28,740
+الـZoonableucida remained intactHowever, until the
+
+172
+00:12:28,740 --> 00:12:31,140
+embryo arrives to the uterus
+
+173
+00:12:40,420 --> 00:12:43,160
+وخدوا بالكوا مهم جدا .. هنعرف كمان شوية شو هي
+
+174
+00:12:43,160 --> 00:12:46,000
+أهمية الـ Zoonopathy ده مهم جدا الـ Zoonopathy ده
+
+175
+00:12:46,000 --> 00:12:51,020
+تبقى عشان مايصيرش تفتت للخلايا ويصير تفرق للخلايا
+
+176
+00:12:51,020 --> 00:12:54,980
+وبالتالي أفقد الجنين لأنه خلال عملية انتقال البيضة
+
+177
+00:12:54,980 --> 00:12:58,800
+المخصبة بحكي بشكل طبيعي من قناة فلوف إلى الرحم
+
+178
+00:12:58,800 --> 00:13:04,300
+بتبرم بعويقات كثيرة أقلها حركة السيليا فتصور لو أن
+
+179
+00:13:04,300 --> 00:13:07,980
+هذه الخلايا الـ Empyrenic Stem Cellاللي مش موجود
+
+180
+00:13:07,980 --> 00:13:11,860
+حولها الزنباليسيدا، هيصيرها تفتت و تفرق، بالتالي،
+
+181
+00:13:11,860 --> 00:13:15,680
+هيصير المحصلة انهائية Zero مافي عند الـ embryo
+
+182
+00:13:15,680 --> 00:13:19,340
+completely embryo الـ embryo تبقى في جزء الانبولار
+
+183
+00:13:19,340 --> 00:13:24,200
+من اليوتران تيوب تلت أيام، يعني ببدأ في منطقة
+
+184
+00:13:24,200 --> 00:13:27,840
+الانبولار الخاصة بالفلوبيان تيوب تلت أيام، يعني
+
+185
+00:13:27,840 --> 00:13:31,740
+البوايدة المخصبة تجلس في فلوبيان تيوب، وهي المرحلة
+
+186
+00:13:31,740 --> 00:13:34,980
+اللي هتنتقل منها، المسافة اللي هتقطعها، حوالي تلت
+
+187
+00:13:34,980 --> 00:13:39,120
+أيامIt then crossed the isthmus portion of the
+
+188
+00:13:39,120 --> 00:13:42,180
+tube in the little of eight hours يعني بوايدة
+
+189
+00:13:42,180 --> 00:13:45,160
+خُصبت في الطولة الأول الأعلى من ال fallopian tube،
+
+190
+00:13:45,160 --> 00:13:49,140
+هذا في الوضع الطبيعي، هتستمر و هتتدهرج لمدة زمانية
+
+191
+00:13:49,140 --> 00:13:52,840
+تقدر بتلت أيام، علشان تقطع طول ال fallopian tube
+
+192
+00:13:53,340 --> 00:13:56,560
+هتصل إلى منطقة المضيق وهو المنطقة اللتي تفصل
+
+193
+00:13:56,560 --> 00:13:59,700
+fallopian tube عن بداية الرحم واللي سميتها في ال
+
+194
+00:13:59,700 --> 00:14:04,020
+chapter الأول isthmus عشان تخترق ال isthmus و تعمل
+
+195
+00:14:04,020 --> 00:14:07,360
+scabbing لل isthmus أو entering لل isthmus تاخد
+
+196
+00:14:07,360 --> 00:14:11,780
+فقط 8 ساعات Under the influence of progesterone
+
+197
+00:14:11,780 --> 00:14:16,480
+neutral tube junction relaxation contraction
+
+198
+00:14:16,480 --> 00:14:20,720
+relaxation those allow the embryo to enter the
+
+199
+00:14:20,720 --> 00:14:23,860
+uterine cavityتحت تأثير الـ Progesterone الذي
+
+200
+00:14:23,860 --> 00:14:27,960
+يُفرز بشكل مستمر تحت تأثير انقباض وارتخاء العضلات
+
+201
+00:14:27,960 --> 00:14:32,840
+الخاصة بالرحم والأنابيب المتعلقة بالجهاز الـ
+
+202
+00:14:32,840 --> 00:14:38,280
+genital الـ reproductive system يسمح بدخول ال
+
+203
+00:14:38,280 --> 00:14:44,680
+embryo إلى الرحم، طالما دخل الرحم، إذن هيتكون معدل
+
+204
+00:14:44,680 --> 00:14:49,750
+عملية ال implantationCouples of day من ستة لات ستة
+
+205
+00:14:49,750 --> 00:14:53,110
+تقيد day after fertilization the embryo implanted
+
+206
+00:14:53,110 --> 00:14:56,150
+in the mid portion of the posterior wall of the
+
+207
+00:14:56,150 --> 00:15:01,310
+uterus يعني بعد حوالي ست أيام على الأقل إلى تلت
+
+208
+00:15:01,310 --> 00:15:05,110
+أيام على الأكثر من عملية ال fertilization المفروض
+
+209
+00:15:05,110 --> 00:15:10,250
+المفروض يكون الجنين قطع كل المسافة الخاصة بال
+
+210
+00:15:10,250 --> 00:15:14,490
+Fallopian tube وقطع الإزمس ووصل لمنطقة معينة عشان
+
+211
+00:15:14,490 --> 00:15:18,440
+يصيله implantation فيهبطن في الرحم وفي جدار الرحم
+
+212
+00:15:18,440 --> 00:15:22,500
+وفي المنطقة بيسموها بالضبط middle portion of
+
+213
+00:15:22,500 --> 00:15:27,120
+posterior wall of the uterus يعني لو صارت طلقاح
+
+214
+00:15:27,120 --> 00:15:34,040
+يوم 13 هتحسب الزوجة 13 14 15 16 17 18 19 20 في
+
+215
+00:15:34,040 --> 00:15:37,960
+اليوم ال 20 المفروض الجنين يكون صارله implantation
+
+216
+00:15:37,960 --> 00:15:41,760
+هذا الوضع الطبيعي الوضع الطبيعي علشان كده معظم
+
+217
+00:15:41,760 --> 00:15:45,970
+المراكز اللي بتعمل حق مجهريبتطلج الجنين في اليوم
+
+218
+00:15:45,970 --> 00:15:49,050
+بعد اليوم التالت يا إما الرابع، يا إما الخامس، يا
+
+219
+00:15:49,050 --> 00:15:53,610
+إما السادس علشان يحاكي الوضع الطبيعي during this
+
+220
+00:15:53,610 --> 00:15:57,330
+time خلال هذه الأيام، الـ6 إلى الـ8 أيام بعد عملية
+
+221
+00:15:57,330 --> 00:16:00,150
+ال fertilization الـZoona Pellucida بيصير فيها
+
+222
+00:16:00,150 --> 00:16:04,690
+تغير في تركيبها علشان تلائم المرحلة الجديدة تغير
+
+223
+00:16:04,690 --> 00:16:10,650
+في تركيبها تبدأ يصير فيها تغير علشان تبدأ يصيلها
+
+224
+00:16:10,650 --> 00:16:14,940
+عملية hatching شو يعني hatching؟ يعني openingطبعا
+
+225
+00:16:14,940 --> 00:16:18,580
+اتروا contribution from the blastomera and the
+
+226
+00:16:18,580 --> 00:16:20,900
+maternal reproductive tissue and this change
+
+227
+00:16:20,900 --> 00:16:24,120
+facilitated the transport and differentiation of
+
+228
+00:16:24,120 --> 00:16:26,560
+the embryo هذه مهمة جدا التغييرات اللي بتصير في
+
+229
+00:16:26,560 --> 00:16:29,120
+الزونا بليوسيدا لأن المفروض الزونا بليوسيدا ما
+
+230
+00:16:29,120 --> 00:16:33,440
+تبقى rigid ما تبقى hard لفترة زمنية طويلة مهمة في
+
+231
+00:16:33,440 --> 00:16:38,640
+مرحلة الانتقال ولكن بمجرد حدوث ووصول إلى مرحلة ال
+
+232
+00:16:38,640 --> 00:16:42,950
+implantation لازم يصير فيها changingأو يصير فيها
+
+233
+00:16:42,950 --> 00:16:49,310
+thinning علشان تبدأ وتسمح لل embryo بالخروج طبعا
+
+234
+00:16:49,310 --> 00:16:54,510
+بعد ما يصل ال embryo لبطانة الرحم أو الرحم أو
+
+235
+00:16:54,510 --> 00:16:57,590
+تجويف الرحم تبدأ ال zona pellucida بتعمل hatching
+
+236
+00:16:57,590 --> 00:17:01,610
+أو تعمل removing أو تعمل opening تمهيد لل
+
+237
+00:17:01,610 --> 00:17:06,110
+implantation وعملية وجود ثقوب وفتح ثقوب في zona
+
+238
+00:17:06,110 --> 00:17:10,270
+pellucida بنسمي هذه العملية hatching أو بنسميها
+
+239
+00:17:10,270 --> 00:17:16,750
+plastocyst hatchingHatching يعني poor formation
+
+240
+00:17:16,750 --> 00:17:21,150
+متى بيبدأ الهاتشينج؟ بعد تمان أيام من عملية
+
+241
+00:17:21,150 --> 00:17:26,810
+التلقيح و ذلك بمجرد وصول الويضة الملقح اللي صارت
+
+242
+00:17:26,810 --> 00:17:30,490
+embryo إلى تجويف الرحمة a small region of the
+
+243
+00:17:30,490 --> 00:17:33,150
+navel used a huge one directly over the inner cell
+
+244
+00:17:33,150 --> 00:17:37,250
+mass in the mammalian for example, the sole and
+
+245
+00:17:37,250 --> 00:17:42,240
+the plosocyst embeddedfrom the hole يعني بمعنى آخر
+
+246
+00:17:42,240 --> 00:17:45,400
+إن الـ zoonapalus ده كمية كبيرة ومناطق معينة من
+
+247
+00:17:45,400 --> 00:17:50,280
+الـ zoonapalus ده تتحطم تتفتح هذا يسمح بيصيرها
+
+248
+00:17:50,280 --> 00:17:54,540
+dissolving بمعنى آخر يسمح بخروج الـ plastocyst و
+
+249
+00:17:54,540 --> 00:18:00,040
+يحدث لها direct contact مع البطانة الرحم مما يمهد
+
+250
+00:18:00,040 --> 00:18:04,060
+لعملية ال implantation يعني كأنه بيصير hole أو
+
+251
+00:18:04,060 --> 00:18:10,040
+pores في الرحم في الرحم بيصير عندي حاجة بتسميهاThe
+
+252
+00:18:10,040 --> 00:18:13,260
+trophoectoderm projections then contact with the
+
+253
+00:18:13,260 --> 00:18:16,180
+endomaterium epithelium cell as the process of
+
+254
+00:18:16,180 --> 00:18:19,580
+implantation الـTrophoectoderm هي عبارة عن نوع من
+
+255
+00:18:19,580 --> 00:18:22,260
+أنواع الخلايا الموجودة في الـembryo، إذا بتذكروا
+
+256
+00:18:22,260 --> 00:18:26,600
+في المحاضرة السابقة الـTrophoectoderm وIntoderm
+
+257
+00:18:26,600 --> 00:18:30,860
+وMesoderm هذا الـTrophoectoderm هي التي تبدأ كبروز
+
+258
+00:18:30,860 --> 00:18:34,420
+تتحد مع بطانط الرحم، علشان تبدأ تمهيد
+
+259
+00:18:34,420 --> 00:18:37,800
+للـimplantationفي enzymatic activity around the
+
+260
+00:18:37,800 --> 00:18:41,400
+enter trophoplast soon beginning to dissolve the
+
+261
+00:18:41,400 --> 00:18:44,180
+rest of the zona pellucida بعد ما تبدأ ال
+
+262
+00:18:44,180 --> 00:18:48,060
+projection تظهر و تصير contact مع ال endometrium
+
+263
+00:18:48,060 --> 00:18:52,080
+of the epithelium cell في بعض التغيرات الإنزيمية
+
+264
+00:18:52,080 --> 00:18:56,560
+والنشاطات الإنزيمية التي تبدأ في الحدوث مما يمهد
+
+265
+00:18:56,560 --> 00:19:00,980
+إلى اختفاء ما تبقى من الzona pellucida وتحلولها
+
+266
+00:19:00,980 --> 00:19:07,270
+هذا بالنسبة إلى عملية الحطنوكيف تتم عملية انتقال
+
+267
+00:19:07,270 --> 00:19:13,290
+البويضة بعد عملية التلقيح الطبيعي في الصورة
+
+268
+00:19:13,290 --> 00:19:16,130
+التالية بتوضح عند البويضة صار لها عملية
+
+269
+00:19:16,130 --> 00:19:20,130
+implantation اعفوا صار لها عملية ovulation ثم في
+
+270
+00:19:20,130 --> 00:19:23,830
+النهاية implantation ال ovulation للبويضة البويضة
+
+271
+00:19:23,830 --> 00:19:28,550
+صارت بويضة طبعا ماضجة في المبيض صار لها ovulation
+
+272
+00:19:28,550 --> 00:19:32,030
+في صار contact بين ال male و ال female صار عند ال
+
+273
+00:19:32,030 --> 00:19:36,630
+fertilizationالفيرتاليزيشن صار عندى 2 nuclei فداني
+
+274
+00:19:36,630 --> 00:19:41,610
+الزيجوت تطورت من مادة إلى تكوين 1 cell بعدين 2
+
+275
+00:19:41,610 --> 00:19:46,730
+cell بعدين 4 cell بعدين 8 cell بعدين موريلا هي من
+
+276
+00:19:46,730 --> 00:19:51,090
+أكتر من 8 خلايا إلى 16 خلية بعدين ال plasticest
+
+277
+00:19:51,090 --> 00:19:56,350
+بعدين بعد 8 أيام صار عملية ال implantation في جدار
+
+278
+00:19:56,350 --> 00:20:02,610
+الرحم في جدار الرحم هذه عبارة عن الصورالتي تحدد أو
+
+279
+00:20:02,610 --> 00:20:06,090
+الصورة التي تحدد مراحل عملية انتقال البويضة بعد
+
+280
+00:20:06,090 --> 00:20:09,270
+التخصيف من الـ fallopian tube إلى بيطانة الرحل
+
+281
+00:20:09,270 --> 00:20:13,450
+طبعا الصورة السفلية بتحدد كيف بيصير عندي عملية
+
+282
+00:20:13,450 --> 00:20:18,530
+removing لل half of number of chromosome من أجل
+
+283
+00:20:18,530 --> 00:20:23,110
+ظهور ال first و second polar body لأنه قلنا أن أول
+
+284
+00:20:23,110 --> 00:20:27,370
+علامة من عمليات نجاح الحقن المجهريأو عمليات
+
+285
+00:20:27,370 --> 00:20:32,190
+التلقيح بشكل عام هي ظهور الـ second polar bond طيب
+
+286
+00:20:32,190 --> 00:20:35,810
+الـ Zoonapolysida حكينا عنها بكمية كبيرة جدا ما هي
+
+287
+00:20:35,810 --> 00:20:39,850
+أهميتها؟ الـ Zoonapolysida لها أهمية كبيرة جدا شو
+
+288
+00:20:39,850 --> 00:20:43,870
+هي أهميتها؟ لماذا تستخدم؟ وكيف تستخدم؟ الـ
+
+289
+00:20:43,870 --> 00:20:47,670
+Zoonapolysida هي عبارة عن طبقة رقيقة في البداية
+
+290
+00:20:47,670 --> 00:20:51,770
+تحيط بالبوايدة لتحمل بوايدة وتسهل عملية ال
+
+291
+00:20:51,770 --> 00:20:55,480
+connection ما بين البوايدةوالوسط الخارجي أو المحيط
+
+292
+00:20:55,480 --> 00:20:59,700
+الخارجي أو البيئة الخارجية كما أسلفنا سابقًا هل
+
+293
+00:20:59,700 --> 00:21:03,620
+لها عوامل أخرى وظائف أخرى؟ أكيد لها وظائف أخرى
+
+294
+00:21:03,620 --> 00:21:06,720
+وظائف شتة الـ Zoonopelucida بنرمز إلى بالـ ZB
+
+295
+00:21:06,720 --> 00:21:10,300
+وبتتكون في الغالب من sulphide glycoprotein يعني
+
+296
+00:21:10,300 --> 00:21:14,440
+هتبارع عن ال protein plus carbohydrate الـ
+
+297
+00:21:14,440 --> 00:21:16,720
+Zoonopelucida بتلعب دور كبير جدًا في عملية ال
+
+298
+00:21:16,720 --> 00:21:19,940
+protection بتلعب دور كبير جدًا في عملية ال embryo
+
+299
+00:21:19,940 --> 00:21:25,700
+developmentبتلعب دور كبير جدا في عملية step by
+
+300
+00:21:25,700 --> 00:21:29,000
+step أو point by point أول حاجة الـ function
+
+301
+00:21:29,000 --> 00:21:32,080
+الأساسية للـ Zoonopelucida بعد ال fertilization
+
+302
+00:21:32,080 --> 00:21:35,860
+إنها بتعمل protection للـ embryo وبتعمل إليه
+
+303
+00:21:35,860 --> 00:21:39,480
+maintenance of its integrity مهم جدا لأن الـ
+
+304
+00:21:39,480 --> 00:21:44,420
+Zoonopelucida إنها بتحمل الجنين بتحمل خلايا
+
+305
+00:21:44,420 --> 00:21:48,240
+الجنينية ما بتخلي الخلايا الجنينية متفرقة مبعثرة
+
+306
+00:21:48,240 --> 00:21:53,190
+فبالتالي تبقىالزونابلوسيدا أشهر وظيفة لها بعد ال
+
+307
+00:21:53,190 --> 00:21:56,190
+fertilization هي حماية الجنين والمحافظة على
+
+308
+00:21:56,190 --> 00:22:01,170
+التراكيب الداخلية الخاصة فيه الزونابلوسيدا هي التي
+
+309
+00:22:01,170 --> 00:22:05,250
+تسمح بعملية ال maturation لل oocyte في البداية
+
+310
+00:22:05,250 --> 00:22:12,160
+الزونابلوسيدا تعتبر عامل مهم جدا حيث تسمحليتمام
+
+311
+00:22:12,160 --> 00:22:15,360
+عملية الـ Fertilization من خلال وجود Receptor خاصة
+
+312
+00:22:15,360 --> 00:22:18,140
+بالـ spermatozoa هذه الـ Receptor موجودة في
+
+313
+00:22:18,140 --> 00:22:20,900
+الزونابليوس ده الـ three لأنه جُلنا الزونابليوس ده
+
+314
+00:22:20,900 --> 00:22:24,540
+أكثر من طبقة الـ zoonabelius ده هي التي تسمح
+
+315
+00:22:24,540 --> 00:22:28,260
+بعملية الـ Acrosome reaction يعني عملية ال
+
+316
+00:22:28,260 --> 00:22:32,260
+fertilization مش sperm ارتبط ببوايضة فقط لأ sperm
+
+317
+00:22:32,260 --> 00:22:36,120
+وصلت للبوايضة ارتبط بال Receptor نشطت البوايضة ال
+
+318
+00:22:36,120 --> 00:22:39,750
+Acrosome reaction علشان يساعد على الاختراقفمهم جدا
+
+319
+00:22:39,750 --> 00:22:43,030
+after fertilization the modified zona pellucida
+
+320
+00:22:43,030 --> 00:22:47,090
+prevent any additional sperm from the arrival to
+
+321
+00:22:47,090 --> 00:22:52,030
+the zygote or another penetration يعني شفنا
+
+322
+00:22:52,030 --> 00:22:55,190
+وظيفتها قبل ال fertilization وشفنا وظيفتها بعد ال
+
+323
+00:22:55,190 --> 00:22:58,210
+fertilization قبل ال fertilization حماية البويضة
+
+324
+00:22:58,210 --> 00:23:03,950
+تطوير البويضة تسهيل عملية ال fertilization كمان
+
+325
+00:23:03,950 --> 00:23:07,450
+تنشيط الأكروزمراكتش هذا كلها before fertilization
+
+326
+00:23:07,450 --> 00:23:10,960
+after fertilizationتعمل على منع الـ polyspermia
+
+327
+00:23:10,960 --> 00:23:17,080
+injection أو fertilize the oocyte by two sperms من
+
+328
+00:23:17,080 --> 00:23:20,460
+خلال تغيير الـ receptor أيضًا بتحافظ على الجنين زي
+
+329
+00:23:20,460 --> 00:23:22,980
+ما جُنّا و هي ال main function of Zoonopelucida
+
+330
+00:23:22,980 --> 00:23:27,500
+خلال المراحل المتقدمة أو المراحل المبكرة من مراحل
+
+331
+00:23:27,500 --> 00:23:34,060
+انقسام الجنة الـ Zoonopelucida بتعمل كبورز أو كشرط
+
+332
+00:23:34,060 --> 00:23:39,880
+مرور بالضبط تتحكم بما يدخل إلى الخليةوتمنع المواد
+
+333
+00:23:39,880 --> 00:23:43,360
+الأخرى من الدخول إلى الخلية وذلك بناء على إحتياج
+
+334
+00:23:43,360 --> 00:23:48,060
+الخلية بالضبط تعمل زي إشارة المورور تسمح بدخول
+
+335
+00:23:48,060 --> 00:23:52,440
+مواد وتمنع دخول مواد أخرى بناء على إحتياج الجنين
+
+336
+00:23:53,610 --> 00:23:57,350
+طبعا بسبب عدم وجود أو فقدان الـ Zoonopelucida
+
+337
+00:23:57,350 --> 00:24:00,250
+الحالية بتسميها hostocompatibility وهي النوع من
+
+338
+00:24:00,250 --> 00:24:02,530
+أنواع الـ human leukocyte antigen الـ
+
+339
+00:24:02,530 --> 00:24:06,190
+Zoonopelucida serve as immunological pairs between
+
+340
+00:24:06,190 --> 00:24:10,590
+mother and the antigenetical different embryo بسبب
+
+341
+00:24:10,590 --> 00:24:13,170
+فقدان الـ Zoonopelucida الـ human leukocyte
+
+342
+00:24:13,170 --> 00:24:17,670
+antigen فبتعمل كحاجز مناعي يحمل جنين ويحمل أم
+
+343
+00:24:17,670 --> 00:24:21,770
+Zoonopelucida بتعمل على تثييل الـ differentiation
+
+344
+00:24:21,770 --> 00:24:27,680
+للـ trophoplastic cell it is normally prevent
+
+345
+00:24:27,680 --> 00:24:31,120
+premature implantation of the cleavage embryo into
+
+346
+00:24:31,120 --> 00:24:33,380
+the wall of the uterine tube طبعا الـ
+
+347
+00:24:33,380 --> 00:24:38,160
+Zoonableucida وجودها ووجودها بشكل hard إلى حد ما
+
+348
+00:24:38,160 --> 00:24:41,220
+في أول أربع أيام إلى تلت أيام من ال fertilization
+
+349
+00:24:41,220 --> 00:24:45,720
+تمنع تحافظ على الجنين وتمنع حدوث implantation مبكر
+
+350
+00:24:45,720 --> 00:24:49,740
+في منطقة غير معدة زي حدوث ال implantation في منطقة
+
+351
+00:24:49,740 --> 00:24:52,520
+ال fallopian tube مما يؤدي إلى حدوث ectopic
+
+352
+00:24:52,520 --> 00:24:55,250
+pregnancyيعني أحد أسباب الـ ectopic pregnancy
+
+353
+00:24:55,250 --> 00:25:01,650
+الخلل في الزونا بليوسيدا طيب وصلت حرفنا أهمية
+
+354
+00:25:01,650 --> 00:25:05,190
+الزونا بليوسيدا ال function الخاصة فيها بعد كده
+
+355
+00:25:05,190 --> 00:25:10,530
+كيف يمكن أن نعمل على ترقيق الزونا بليوسيدا بمعنى
+
+356
+00:25:10,530 --> 00:25:14,210
+آخر في الحقن المجهري جاب العملية ال embryo
+
+357
+00:25:14,210 --> 00:25:17,750
+transfer أو إرجاع ال embryo لازم أعمل حاجة بنسميها
+
+358
+00:25:17,750 --> 00:25:22,150
+thinning يعني بمعنى آخرترفيه أو ترقيق الـ
+
+359
+00:25:22,150 --> 00:25:25,370
+Zoonopelucida ليه بنرقيق الـ Zoonopelucida؟ علشان
+
+360
+00:25:25,370 --> 00:25:29,030
+أسمح للـ Zoonopelucida إنها تتلاشى ببساطة جدا
+
+361
+00:25:29,030 --> 00:25:32,990
+وبسهولة جدا دون تأخير وتساهم في عملية الـ
+
+362
+00:25:32,990 --> 00:25:37,190
+Implantation حاجة بنسميها Assist Hatching in Exit
+
+363
+00:25:37,190 --> 00:25:40,890
+يا إما بعمل Thinning، ترقيق، يا إما بعمل Pouring،
+
+364
+00:25:40,890 --> 00:25:45,010
+هنشوف كيف بعمل Pouring الـ Implantation خلال الحقن
+
+365
+00:25:45,010 --> 00:25:50,990
+المجهري يحتاج إلى عملية بنسميهاهاتشينج تكنيك وهي
+
+366
+00:25:50,990 --> 00:25:55,430
+عمل ثقوب في جدار الزونابلوسيدا وهذا الثقوب ما
+
+367
+00:25:55,430 --> 00:25:58,670
+بتكون غائرة أو بعض الأحيان بتسميها filling of
+
+368
+00:25:58,670 --> 00:26:02,350
+zoonablusida failure of the embryo to escape the
+
+369
+00:26:02,350 --> 00:26:05,390
+zoonablusida is believed to be related to low
+
+370
+00:26:05,390 --> 00:26:08,650
+implantation rate for poor prognosis patients and
+
+371
+00:26:08,650 --> 00:26:14,620
+the main goal of assistant hatchedis overcome this
+
+372
+00:26:14,620 --> 00:26:19,620
+obstacle يعني بيقول لي ببساطة جدا ان في حالات يكون
+
+373
+00:26:19,620 --> 00:26:25,580
+الإجزي فشلت في الحصول على جنين صحيح أو جنين سليم
+
+374
+00:26:25,580 --> 00:26:28,100
+بعد عملية ال implantation بعد عملية ال
+
+375
+00:26:28,100 --> 00:26:32,630
+fertilizationوبعد عملية الـ embryo transfer بكون
+
+376
+00:26:32,630 --> 00:26:37,270
+سببها بشكل أساسي إن زونابليوسيدا فشلت في التكسّر
+
+377
+00:26:37,270 --> 00:26:42,590
+أو زونابليوسيدا ما زالت قوية صلبة منعت الجنين من
+
+378
+00:26:42,590 --> 00:26:46,530
+الخروج فهذا بنسميها embryo to escape prevent the
+
+379
+00:26:46,530 --> 00:26:49,810
+embryo or failure the embryo to escape from
+
+380
+00:26:49,810 --> 00:26:53,670
+زونابليوسيدا بقى ال embryo محضون داخل زونابليوسيدا
+
+381
+00:26:53,670 --> 00:26:58,190
+زونابليوسيدا بقيت كما هي قويةلا تسمح بخروج الـ
+
+382
+00:26:58,190 --> 00:27:01,470
+Embryo فبالتالي فشلت عملية الحقن المجهري في الوصول
+
+383
+00:27:01,470 --> 00:27:06,910
+إلى الـ True Embryo داخل الرحم فبالتالي ممكن أن
+
+384
+00:27:06,910 --> 00:27:10,110
+أتغلب على هذا الموضوع من خلال عملية قوية جدا
+
+385
+00:27:10,110 --> 00:27:16,230
+بنسميها Assist Hatching حاجة برمزولها بالرمز A H
+
+386
+00:27:16,230 --> 00:27:21,530
+طبعا هذه العملية بتحدث في الـ Assist Reproductive
+
+387
+00:27:21,530 --> 00:27:25,490
+Technology عملية مهمة جدابصير من خلالها عمل pores
+
+388
+00:27:25,490 --> 00:27:27,890
+في الـ zona pellucida إما هذه ال pores بتكون
+
+389
+00:27:27,890 --> 00:27:31,410
+mechanical pore أو chemical pore يعني ممكن أستخدم
+
+390
+00:27:31,410 --> 00:27:35,950
+مواد كيميائية و أنزيمات أو ممكن أستخدم طرق
+
+391
+00:27:35,950 --> 00:27:39,610
+ميكانيكية باستخدام ال injection needle و هنشوفها
+
+392
+00:27:39,610 --> 00:27:42,830
+كمان شوية كيف أنا ممكن أستخدم ال injection needle
+
+393
+00:27:43,590 --> 00:27:48,050
+إذا الـ Assisted Hatching في الإجزي بيصير بعد ال
+
+394
+00:27:48,050 --> 00:27:51,410
+fertilization بعد اليوم الخامس من ال fertilization
+
+395
+00:27:51,410 --> 00:27:53,490
+يعني لو صار ال fertilization و ال injection في
+
+396
+00:27:53,490 --> 00:27:57,010
+اليوم الأول يعني المفروض تصير في اليوم الخامس و هو
+
+397
+00:27:57,010 --> 00:27:59,810
+يوم الأربعة مثلا إذا كان يوم السبت هتصير يوم
+
+398
+00:27:59,810 --> 00:28:03,550
+الأربعة وظيفتها أن تعمل pores في zona pellucida
+
+399
+00:28:03,550 --> 00:28:07,270
+علشان تسمح للجنين بالخروج أين دقيقاته و نقله إلى
+
+400
+00:28:07,270 --> 00:28:11,870
+الرحم هل كل الحالات أعملها Assisted Hatching ولا
+
+401
+00:28:11,870 --> 00:28:16,350
+حالات معينة؟في حالات معينة مهم جدا بل لاجب يجب
+
+402
+00:28:16,350 --> 00:28:20,910
+بشكل واجب أنه يعمل assist hatching قبل ما يعمل
+
+403
+00:28:20,910 --> 00:28:25,090
+embryo transfer من أشهر هذه الحالات السيدات اللي
+
+404
+00:28:25,090 --> 00:28:28,730
+عندهم recurrent failure of embryo implantation
+
+405
+00:28:28,730 --> 00:28:32,150
+after embryo transfer يعني عند سيدة خضعت للإجزي
+
+406
+00:28:32,150 --> 00:28:36,170
+تلت أربع أو خمس مرات كل مرة برجع جنين بيصير عنده
+
+407
+00:28:36,170 --> 00:28:39,030
+فشل في ال implantation فبالتالي النتيجة negative
+
+408
+00:28:39,480 --> 00:28:42,220
+رجعت الجنين لدورة تانية، فشل في الـ Implantation
+
+409
+00:28:42,220 --> 00:28:45,500
+النتيجة نيجاتيف وهي نتيجة البييدا الـCG فهذا معناه
+
+410
+00:28:45,500 --> 00:28:48,020
+أن الـZoonopolisida ما صارش فيها dissolving،
+
+411
+00:28:48,020 --> 00:28:50,720
+partial dissolving فبالتالي ما صار Implantation
+
+412
+00:28:50,720 --> 00:28:55,440
+فلازم أعمل assist hatching جاب العملية لل transfer
+
+413
+00:28:55,440 --> 00:28:59,220
+ال embryo exhibiting thickened Zoonopolisida و لا
+
+414
+00:28:59,220 --> 00:29:04,240
+بحكم لجد Zoonopolisida very thick مقاومة لعملية ال
+
+415
+00:29:04,240 --> 00:29:08,540
+penetration فلازم أعملHatching السيدات اللي عندهم
+
+416
+00:29:08,540 --> 00:29:12,260
+advanced age أكتر من 37 سنة السيدات اللي عندهم
+
+417
+00:29:12,260 --> 00:29:16,580
+مستوى ال FSH عالي جدا السيدات .. ال cycle اللي
+
+418
+00:29:16,580 --> 00:29:18,480
+بدأت من ال crime preservation شو يعني crime
+
+419
+00:29:18,480 --> 00:29:21,160
+preservation؟ إن السيدة خضعت ل protocol
+
+420
+00:29:21,160 --> 00:29:26,500
+stimulation أخرجت 35 بوادة حقلت 10 بوادة و الباقي
+
+421
+00:29:26,500 --> 00:29:32,280
+25 عملتلهم preservation جمّتهمالدورة التانية مش
+
+422
+00:29:32,280 --> 00:29:35,940
+هتطبط تخضع لعملية ovulation أو مش هتخضع لعملية
+
+423
+00:29:35,940 --> 00:29:40,040
+stimulation فبضطر باخد من البويضات اللي مخزنة فهذه
+
+424
+00:29:40,040 --> 00:29:43,280
+البويضات طالما مخزنة إذا صار في تغير في تركيب
+
+425
+00:29:43,280 --> 00:29:46,480
+الزونابليوسيدا في ال membrane فبعد عملية الحقل
+
+426
+00:29:46,480 --> 00:29:50,880
+لازم أعمل assist hatching علشان أسمح لل embryo
+
+427
+00:29:50,880 --> 00:29:56,540
+بالخروج بكل بساطة كيف تتم عملية زونابليوسيدا
+
+428
+00:29:56,540 --> 00:30:00,210
+assist hatching أو زونابليوسيدا thinning؟ترفيه
+
+429
+00:30:00,210 --> 00:30:03,910
+الزونابليوسيدا لما اقول thinning بيكون مش كامي مش
+
+430
+00:30:03,910 --> 00:30:07,810
+completely لأ partially completely لأ partially
+
+431
+00:30:07,810 --> 00:30:12,030
+because thinning partially او عمل عدد معين من ال
+
+432
+00:30:12,030 --> 00:30:16,770
+pores او ال holes زونابليوسيدا removal total
+
+433
+00:30:16,770 --> 00:30:20,050
+zoonablusida removal before embryo transfer has
+
+434
+00:30:20,050 --> 00:30:23,690
+been expected to bring out closer contact and
+
+435
+00:30:23,690 --> 00:30:27,350
+communication of the trophoEctoderm of the
+
+436
+00:30:27,350 --> 00:30:31,090
+blastocyst with the endomaterium thereby improving
+
+437
+00:30:31,090 --> 00:30:34,950
+implantation وهذا الهدف الأساسي منها إنه يصير في
+
+438
+00:30:34,950 --> 00:30:38,010
+عندي direct contact ما بين الخلايا الخاصة بالـ
+
+439
+00:30:38,010 --> 00:30:41,930
+embryonic stem cell أو ال embryonic cell و ال
+
+440
+00:30:41,930 --> 00:30:46,250
+endomaterium of female الموجودة في ضلط الرحم مما
+
+441
+00:30:46,250 --> 00:30:49,810
+يحسن عملية ال implantation الـ zoonablusida can be
+
+442
+00:30:49,810 --> 00:30:53,410
+totally removed by chemical or enzymatic method or
+
+443
+00:30:53,410 --> 00:30:58,900
+by using laserيعني انا ممكن اعمل pools او holes او
+
+444
+00:30:58,900 --> 00:31:01,900
+completely removing او partially removing الاربعة
+
+445
+00:31:01,900 --> 00:31:06,080
+بناء على حالة الزيونابلوسيدا من خلال طريقة
+
+446
+00:31:06,080 --> 00:31:10,420
+ميكانيكية طريقة كيميائية او استخدام انزيمات او
+
+447
+00:31:10,420 --> 00:31:16,020
+باستخدام ال laser طلاقات ال laser هناخد اكثر من
+
+448
+00:31:16,020 --> 00:31:19,580
+طريقة جزء هناخده حاليا و الجزء التاني هناخده لما
+
+449
+00:31:19,580 --> 00:31:24,340
+نقول polar body biopsy انوع من انواع التخفيفأول
+
+450
+00:31:24,340 --> 00:31:28,660
+طريقة هي طريقة الـ traditional method وهي عمل
+
+451
+00:31:28,660 --> 00:31:32,600
+pores و holes في الـ zona pellucida من خلال الـ
+
+452
+00:31:32,600 --> 00:31:36,680
+mechanical zona pellucida dissection أو الـ
+
+453
+00:31:36,680 --> 00:31:41,120
+traditional method ببساطة جدا بجيب الطبق اللي فيه
+
+454
+00:31:41,120 --> 00:31:46,320
+الجنين بعد عملية تطوره وانقسامه بوضعه على stage
+
+455
+00:31:46,320 --> 00:31:51,380
+درجة حرارته 37 في منطقة معقمة بنسبة 100% تحت ال
+
+456
+00:31:51,380 --> 00:31:56,760
+inverted microscopeبحمل الجنين وبثبته باستخدام الـ
+
+457
+00:31:56,760 --> 00:31:59,740
+holder أو الـ sucker أو الـ suction holder أو الـ
+
+458
+00:31:59,740 --> 00:32:04,320
+holding tube الموجودة دائما على جهة اليسار اللي
+
+459
+00:32:04,320 --> 00:32:06,920
+أنا كنت بثبت فيها البويضة أثناء عملية ال injection
+
+460
+00:32:06,920 --> 00:32:11,620
+فكده أنا ثبتت الجنين وبجيب ال injection needed
+
+461
+00:32:11,620 --> 00:32:17,540
+اللي كنت أحطن فيها ال sperm بعمل اختراقبعمل اختراق
+
+462
+00:32:17,540 --> 00:32:22,020
+للجنين في الغلاف الخارجي ببدأ من الساعة واحدة و
+
+463
+00:32:22,020 --> 00:32:26,560
+بصل للساعة 11 الساعة واحدة للساعة 11 شو يعني
+
+464
+00:32:26,560 --> 00:32:29,400
+الساعة واحدة للساعة 11؟ لإن الجنين عبارة عن دائرة
+
+465
+00:32:29,400 --> 00:32:35,020
+بقسمها ساعات اتناش ستة تلاتة تسعة انا بدخلت بال
+
+466
+00:32:35,020 --> 00:32:39,300
+needle injection needle من الساعة واحدة هطلع هتخرج
+
+467
+00:32:39,300 --> 00:32:42,680
+ال needle من الساعة 11 بعد كده اعمل releasing لل
+
+468
+00:32:42,680 --> 00:32:49,720
+embryo بإني أخلي ال holder tubeالضغط فيها غير كافي
+
+469
+00:32:49,720 --> 00:32:52,140
+إنه يبدأ يعمل catching للـ embryo فالـ embryo
+
+470
+00:32:52,140 --> 00:32:56,980
+بيصير معلق في ال injection needle باجي بعمل عملية
+
+471
+00:32:56,980 --> 00:33:02,800
+احتكاك بال needle في طرف ال holder tube علشان أعمل
+
+472
+00:33:02,800 --> 00:33:08,240
+تآكل للـ zona pellucida فبهذا الشكل بكون عملت تآكل
+
+473
+00:33:08,240 --> 00:33:11,660
+لجزء من ال zona pellucida وعملت removing أو
+
+474
+00:33:11,660 --> 00:33:15,260
+dissolving هدف نسميها طريقة التآكل أو الطريقة
+
+475
+00:33:15,260 --> 00:33:19,540
+الميكانيكيةطريقة الاحتكاج التي تؤدي لتأكل الزونا
+
+476
+00:33:19,540 --> 00:33:23,720
+بليوسيدا وهي طريقة ميكانيكية خلّينا نشوف بالفيديو
+
+477
+00:33:23,720 --> 00:33:27,460
+كيف تصير هذه الطريقة الميكانيكية اللي من خلالها
+
+478
+00:33:27,460 --> 00:33:31,800
+أنا بتخلص من جزء من الزونا بليوسيدا وهي الـ
+
+479
+00:33:31,800 --> 00:33:38,800
+traditional method طبعا
+
+480
+00:33:38,800 --> 00:33:43,640
+هي عند البويضة عفو للجنين الجنين هذا عند ال holder
+
+481
+00:33:43,640 --> 00:33:47,690
+أو ال suction tubeوهذه ال injection needle أو في
+
+482
+00:33:47,690 --> 00:33:51,370
+بعض الأحيان بيسموها needle الخاصة بعملية
+
+483
+00:33:51,370 --> 00:33:59,730
+zoonablucida dissolving باجي بعمل fixation و بعمل
+
+484
+00:33:59,730 --> 00:34:04,730
+holding لل embryo باستخدام ال holder tube هي
+
+485
+00:34:04,730 --> 00:34:09,610
+الساعة 12 هي الساعة 6 هي الساعة 3 هي الساعة 9 باجي
+
+486
+00:34:09,610 --> 00:34:13,290
+بخترق من الساعة 1 في هذا الاتجاه و بطلع بال needle
+
+487
+00:34:13,290 --> 00:34:17,280
+من الساعة 11إن ما أضرب حوافة في منطقة الزونا
+
+488
+00:34:17,280 --> 00:34:24,100
+باليوسدان الفاتحة دخل
+
+489
+00:34:24,100 --> 00:34:31,160
+بالنيدل المفروض يخرج من الطرف الآخر خرج
+
+490
+00:34:31,160 --> 00:34:34,340
+من الطرف الآخر ما بين الساعة واحدة و اتناشر و خرج
+
+491
+00:34:34,340 --> 00:34:40,600
+ما بين الساعة احداشر و اتناشر بعدين ببدأ يعمل
+
+492
+00:34:40,600 --> 00:34:49,460
+احتكاك بجزء السفلي للولداركدا بيكون بدأ الجنين
+
+493
+00:34:49,460 --> 00:34:52,520
+يخرج زي ما احنا شايفين في هذا المنطقة هذه معناه
+
+494
+00:34:52,520 --> 00:34:56,940
+صار في عدة opening الجنين او الخلايا الـplastomera
+
+495
+00:34:56,940 --> 00:35:00,380
+او الـplastocyst بدأت تنفذ للخارج
+
+496
+00:35:03,860 --> 00:35:09,020
+هذه الفكرة بتسميها ال traditional method او
+
+497
+00:35:09,020 --> 00:35:13,700
+mechanical method for assist hatching فقط لغة هذا
+
+498
+00:35:13,700 --> 00:35:19,360
+كتير الناس بتسويها و مازالت بتحقق نجاحات قوية طيب
+
+499
+00:35:19,360 --> 00:35:24,680
+طب انا عملت hatching و عملت pores او holes في
+
+500
+00:35:24,680 --> 00:35:27,280
+الزولة باليسنا ممكن اعملها جاب العملية ال
+
+501
+00:35:27,280 --> 00:35:32,330
+implantation اه ممكن اعملها طب شو هدفها؟هدفها إن
+
+502
+00:35:32,330 --> 00:35:36,510
+أحصل على مادة وراثية خاصة بالجنين أو أحصل على مادة
+
+503
+00:35:36,510 --> 00:35:40,470
+وراثية خاصة بالأم من أجل الفحوصات الوراثية التي
+
+504
+00:35:40,470 --> 00:35:44,670
+تسمى pre-implantation genetic testing يعني الفحص
+
+505
+00:35:44,670 --> 00:35:49,370
+الجنيني أو الفحص الجيني قبل عملية ال implantation
+
+506
+00:35:49,370 --> 00:35:54,430
+أو الانغراس أو الزراع أو الإعادة ال embryo هذا
+
+507
+00:35:54,430 --> 00:35:58,270
+مصطلح بنسميه polar body biopsy ممكن أخد polar body
+
+508
+00:35:58,270 --> 00:36:01,870
+biopsy يعني أخد جزء من ال polar bodyو أعمله
+
+509
+00:36:01,870 --> 00:36:05,510
+genetic testing فلازم عشان أصل للـ polar body أعمل
+
+510
+00:36:05,510 --> 00:36:08,150
+opening في الـ zoonableucida لأن أحنا عارفين أن
+
+511
+00:36:08,150 --> 00:36:11,670
+البويضة الملقحة فيها two polar body بتكون ما بين
+
+512
+00:36:11,670 --> 00:36:15,690
+البويضة و ما بين ال zoonableucida فلازم أخترق ال
+
+513
+00:36:15,690 --> 00:36:18,910
+zoonableucida عشان أعمل suction لل polar body تحت
+
+514
+00:36:18,910 --> 00:36:23,210
+مصطلح polar body biopsy ال polar body biopsy كان
+
+515
+00:36:23,210 --> 00:36:28,150
+أول ما تم تكوينه في عام و إنجازه في عام 1990 ال
+
+516
+00:36:28,150 --> 00:36:32,200
+polar bodyبيحتوي على المادة الوراثية الخاصة بالأم
+
+517
+00:36:32,200 --> 00:36:35,860
+polar body consists of genetic material related to
+
+518
+00:36:35,860 --> 00:36:39,720
+mother or maternal only خدوا بالكوا من القصة يعنى
+
+519
+00:36:39,720 --> 00:36:43,780
+أي مرض وراثي متعلق بالأم بافحصه من خلال ال polar
+
+520
+00:36:43,780 --> 00:36:48,780
+body أي مرض وراثي متعلق بالجنين بافحصه من خلال ال
+
+521
+00:36:48,780 --> 00:36:50,260
+embryonic cell
+
+522
+00:36:54,000 --> 00:36:56,480
+The analysis polar body can be used to determine
+
+523
+00:36:56,480 --> 00:37:00,860
+chromosomal aniploidy related to maternal meiosis
+
+524
+00:37:00,860 --> 00:37:05,180
+and maternal divide-unbalance translocation
+
+525
+00:37:05,180 --> 00:37:10,320
+chromosome. To detect single gene defect related
+
+526
+00:37:10,320 --> 00:37:13,100
+to who related to the mother related to the
+
+527
+00:37:13,100 --> 00:37:19,100
+maternal allowing for day 3 embryo transfer ممكن
+
+528
+00:37:19,100 --> 00:37:23,980
+أناأستخدم الـ polar body علشان أعمل HLA typing وهي
+
+529
+00:37:23,980 --> 00:37:27,840
+human leukocyte antigen typing وهو التوافق وممكن
+
+530
+00:37:27,840 --> 00:37:33,560
+أفحص من خلالها ال X link disorder خاصة لما نقول X
+
+531
+00:37:33,560 --> 00:37:37,340
+link disorder مفهوم أن معظم الأمراض الوراثية
+
+532
+00:37:37,340 --> 00:37:41,520
+المرتبطة بال X link سواء كانت X link dominant أو X
+
+533
+00:37:41,520 --> 00:37:44,980
+link recessive وعارفينها أن مصدر الخلل بيكون الأم
+
+534
+00:37:44,980 --> 00:37:51,240
+في هذه الحالة أيه ال polar body؟هي الـ GVPD طبعا
+
+535
+00:37:51,240 --> 00:37:55,940
+هذه الـ spindle الـ simply بعدين صار عندى مهاجرة
+
+536
+00:37:55,940 --> 00:37:59,740
+جزء من الخلايا أو عفوا جزء من الكرموزومات إلى
+
+537
+00:37:59,740 --> 00:38:03,280
+الطرف الخلية والجزء الأخر تبقى توني ال fairest
+
+538
+00:38:03,280 --> 00:38:06,760
+polar body بعد ال fertilization أي النواء الذكرية
+
+539
+00:38:06,760 --> 00:38:10,560
+النواء الأنثوية اندمجت صار ال fertilization خرج ال
+
+540
+00:38:10,560 --> 00:38:13,500
+second polar body فانا ممكن أسحب هذا ال polar body
+
+541
+00:38:13,500 --> 00:38:16,520
+و ممكن أسحب اتنين مع بعض هذا له وظيفة و هذا له
+
+542
+00:38:16,520 --> 00:38:22,100
+وظيفةهدف و هدايل و هدف طيب technical aspect of
+
+543
+00:38:22,100 --> 00:38:25,860
+polar body biopsy عرفنا أن ال polar body مهم جدا
+
+544
+00:38:25,860 --> 00:38:29,960
+في تشخيص بعض الأمراض الوراثية الخاصة بالأم بعض
+
+545
+00:38:29,960 --> 00:38:32,120
+الأمراض المتعلقة بال abnormal chromosome
+
+546
+00:38:32,120 --> 00:38:36,980
+structural or number فبالتالي لازم أعمل opening في
+
+547
+00:38:36,980 --> 00:38:40,320
+ال zona pellucida علشان أصل لل polar body و أعمله
+
+548
+00:38:40,320 --> 00:38:44,610
+suction مهم جدا ال timeThe most relevant part of
+
+549
+00:38:44,610 --> 00:38:47,750
+polar body biopsy are timing of biopsy, the
+
+550
+00:38:47,750 --> 00:38:50,050
+opening of zona pellucida, and the removing of
+
+551
+00:38:50,050 --> 00:38:53,470
+polar body يعني تلت مراحل متى أعمل polar body
+
+552
+00:38:53,470 --> 00:38:58,030
+biopsy و لماذا؟ كيف يمكن فتح ال zona pellucida و
+
+553
+00:38:58,030 --> 00:39:01,450
+أعمل opening فيها؟ و كيف يتم إزالة ال polar body؟
+
+554
+00:39:01,450 --> 00:39:05,830
+هذه التلت نقاط الأساسية والمهمة ال timing an
+
+555
+00:39:05,830 --> 00:39:08,510
+oocyte representing a ferrous polar body is
+
+556
+00:39:08,510 --> 00:39:12,150
+usually considered to be metaphysical too يعني أي
+
+557
+00:39:12,150 --> 00:39:16,820
+بويضةيظهر فيها الـ First Polar Body هي بويضة ناضجة
+
+558
+00:39:16,820 --> 00:39:21,860
+وقفت في الـ Metaphase 2 يعني الـ Metaphase الخاص
+
+559
+00:39:21,860 --> 00:39:25,880
+بالإقسام الميوز التاني وتكون صالح لعملية الحقن
+
+560
+00:39:25,880 --> 00:39:29,580
+فبالتالي ممكن أحصل على الـ Polar Body منها الـ
+
+561
+00:39:29,580 --> 00:39:32,160
+Zolopelucida ممكن أعملها Opening من خلال
+
+562
+00:39:32,160 --> 00:39:34,980
+Mechanical زي ما شوفنا قبل شوية الفيديو أو
+
+563
+00:39:34,980 --> 00:39:38,180
+Chemical باستخدام انزين معين هتتكلم عنه وLaser
+
+564
+00:39:38,180 --> 00:39:41,960
+Hatching Opening إنه أنا أستخدم الـ Laser طلقات
+
+565
+00:39:41,960 --> 00:39:46,680
+الـ Laserالـ chemical الـ mechanical أتكلمنا عنه
+
+566
+00:39:46,680 --> 00:39:50,080
+الـ chemical أنه أنا بستخدم solution بيسموه acidic
+
+567
+00:39:50,080 --> 00:39:56,060
+triode solution وهي أول طريقة تم فيها استخدام مادة
+
+568
+00:39:56,060 --> 00:39:59,760
+كيميائية من أجل إزالة جزء من الـ zoonopelucida
+
+569
+00:39:59,760 --> 00:40:04,720
+وعمل zoonopelucida opening هذي استخدموها بعد الـ
+
+570
+00:40:04,720 --> 00:40:09,440
+chemical الـ acidic triode كان بي applied at the
+
+571
+00:40:09,440 --> 00:40:12,870
+embryo stageApplied at the embryo stage, there was
+
+572
+00:40:12,870 --> 00:40:15,690
+an inhibitor effect in the embryonic development
+
+573
+00:40:15,690 --> 00:40:19,570
+when oocyte were exposed to the ascetic triode
+
+574
+00:40:19,570 --> 00:40:22,270
+يعني ال triode أو ال ascetic triode okay أنا ممكن
+
+575
+00:40:22,270 --> 00:40:25,990
+أستخدمه لعمل zoonablucid hatching ولكن ال side
+
+576
+00:40:25,990 --> 00:40:28,410
+effect ايه له او ال disadvantage انه ممكن يعمل
+
+577
+00:40:28,410 --> 00:40:32,710
+inhibition لل embryo development وانا رأسمالي في
+
+578
+00:40:32,710 --> 00:40:36,930
+هذه الحتة ال embryo مش منطق اعمله inhibition لأنه
+
+579
+00:40:36,930 --> 00:40:40,480
+ممكن يعملي abnormalفي الـ embryo development،
+
+580
+00:40:40,480 --> 00:40:42,500
+abnormality في الـ embryo development و أخسر
+
+581
+00:40:42,500 --> 00:40:47,300
+الجنين Therefore, since both oocyte and polar body
+
+582
+00:40:47,300 --> 00:40:50,180
+are sensitive to effect of this acid, zoonia
+
+583
+00:40:50,180 --> 00:40:54,100
+draining by acidic triode solution is unstable for
+
+584
+00:40:54,100 --> 00:40:57,940
+polar body biopsy عشان كده أنا مهمنيش أعمل أو مش
+
+585
+00:40:57,940 --> 00:41:03,200
+لازم أعمل polar body biopsy أو zoonia bilucida
+
+586
+00:41:03,200 --> 00:41:06,800
+opening باستخدام ال chemical material اسمها triode
+
+587
+00:41:06,800 --> 00:41:10,300
+acidأو trial solution اللي هنا بتأثر شكلا سلبية
+
+588
+00:41:10,300 --> 00:41:16,620
+بشكل سلبي على ال embryo وعلى ال oocyte وعلى ال
+
+589
+00:41:16,620 --> 00:41:21,320
+polar body ال laser hatching وهي الطريقة التالية
+
+590
+00:41:21,320 --> 00:41:25,060
+اللتي تستخدم ببساطة جدا ان انا في عندي مطلق لل
+
+591
+00:41:25,060 --> 00:41:29,440
+laser هنشوفها في الفيديو كمان شوية بيجي بيعمل
+
+592
+00:41:29,440 --> 00:41:34,820
+طلقات لل laser في depth معين ب thickness معين بعدد
+
+593
+00:41:34,820 --> 00:41:39,320
+معين كأنه بيعمل thinningو تقشير للـ zona pellucida
+
+594
+00:41:39,320 --> 00:41:44,860
+ببساطة جدا طبعا ال laser assist polar body biopsy
+
+595
+00:41:44,860 --> 00:41:48,240
+is the best method when the oocyte is fixed with
+
+596
+00:41:48,240 --> 00:41:51,180
+the holder capillary يعني بداية زي ما شوفنا في
+
+597
+00:41:51,180 --> 00:41:54,960
+الفيديو بعمل laser hatching إما بعملها للإمبريو أو
+
+598
+00:41:54,960 --> 00:41:58,740
+بعملها للبويضة و طالما أنا بتعمل polar body biopsy
+
+599
+00:41:58,740 --> 00:42:03,520
+إذا بعملها للبويضة الغير ملطحة أو الملطحة بناء أن
+
+600
+00:42:03,520 --> 00:42:07,980
+أنا شو إيه بتشتغل و الأفضل أعملها لالملقحة بعد
+
+601
+00:42:07,980 --> 00:42:11,680
+تكوين وظهور ال tube polar body ال first وال second
+
+602
+00:42:11,680 --> 00:42:17,120
+بعمل fixation ل .. او بعمل حاجة بنسميها fixation ل
+
+603
+00:42:17,120 --> 00:42:22,580
+.. او catching ل ال oocyte باستخدام ال holder tube
+
+604
+00:42:22,580 --> 00:42:26,920
+بعدين باجي بشعاع ال laser بحدد اند الساعة 12 لساعة
+
+605
+00:42:26,920 --> 00:42:31,080
+3 مناطق الطلاقات اللي هيطلق عليها ال laser ب depth
+
+606
+00:42:31,080 --> 00:42:37,000
+معينكأنه بعملي تقشير للـ zona pellucida هنشوفها
+
+607
+00:42:37,000 --> 00:42:40,820
+بالفيديو ال opening تقريبا بتكون ال size تبعها من
+
+608
+00:42:40,820 --> 00:42:44,520
+15 إلى 25 ميكرو متر و بتكون ما بين الساعة التانية
+
+609
+00:42:44,520 --> 00:42:47,100
+والساعة التلاتة الساعة التانية والساعة التلاتة
+
+610
+00:42:47,100 --> 00:42:53,120
+طبعا بيصير عندي thinning لل zona pellucida and by
+
+611
+00:42:53,120 --> 00:42:57,280
+pushing the biopsy capillary into prevental space
+
+612
+00:42:57,280 --> 00:43:02,280
+both polar body can be removed togetherيعني بمعنى
+
+613
+00:43:02,280 --> 00:43:08,640
+أخر بعد أن أنا معملت holding و fixation ل ال .. ال
+
+614
+00:43:08,640 --> 00:43:13,080
+oocyte استخدام ال .. ال holder tube و أعرضت طلقات
+
+615
+00:43:13,080 --> 00:43:15,600
+ال laser للمنطقة اتنين و تلاتة فصار في عندي فتحة
+
+616
+00:43:15,600 --> 00:43:18,260
+في المنطقة ما بين الساعة اتنين و تلاتة باجب ال
+
+617
+00:43:18,260 --> 00:43:22,380
+aspiration tube بدخل من خلال الفتحة و بعمل suction
+
+618
+00:43:22,380 --> 00:43:25,960
+لل polar body ممكن أعمل لل polar body الأول ممكن
+
+619
+00:43:25,960 --> 00:43:29,160
+أعمل لل polar body التاني كل واحد على حد أو ممكن
+
+620
+00:43:29,160 --> 00:43:35,420
+أعملهم مع بعضطبعا اعمل .. بقول في trick فني انه
+
+621
+00:43:35,420 --> 00:43:41,900
+بقول لي ببساطة و انت داخل ال aspiration tube اعملت
+
+622
+00:43:41,900 --> 00:43:46,240
+catching لل first polar body حاول ارجع جدّم شوية و
+
+623
+00:43:46,240 --> 00:43:49,920
+بعدين اعمل aspiration لان عملية التقديم بتحرك ال
+
+624
+00:43:49,920 --> 00:43:52,740
+first polar body لان عارفين احنا ال first polar
+
+625
+00:43:52,740 --> 00:43:55,880
+body بيكون في الأول يلي من جهة اليسار ال second
+
+626
+00:43:55,880 --> 00:43:58,720
+polar body يعني انت كأنك بتطلع في الأول ال second
+
+627
+00:43:58,720 --> 00:44:02,820
+polar bodyبعدين بتطلع ال first polar body لما تعمل
+
+628
+00:44:02,820 --> 00:44:06,100
+catching للفئر ال second polar body اعمل عملية
+
+629
+00:44:06,100 --> 00:44:11,420
+ادخال ل ال aspiration tube بزيادة شوية عشان يتحرك
+
+630
+00:44:11,420 --> 00:44:16,560
+ال first polar body من مكانه و يصير سهل الحركة من
+
+631
+00:44:16,560 --> 00:44:21,080
+أجل تثير عملية ال suction الخاصة فيهThe procedure
+
+632
+00:44:21,080 --> 00:44:26,240
+is accurate, reproducible and safe and it also
+
+633
+00:44:26,240 --> 00:44:28,360
+reduces the number of cells which cannot be
+
+634
+00:44:28,360 --> 00:44:32,080
+diagnosed as a result of a technical problem
+
+635
+00:44:32,080 --> 00:44:35,840
+during biopsy procedure يعني مهم جدا بيقولك هذا
+
+636
+00:44:35,840 --> 00:44:40,560
+الطريقة طريقة ال laser hatching طريقة سهلة آمنة
+
+637
+00:44:40,560 --> 00:44:45,920
+مضمونة إلى حد ما تقلل عدد الخلال التي تخرج من ال
+
+638
+00:44:45,920 --> 00:44:51,110
+embryo أو البوايدة خلالالـ Polar Body Biopsy والتي
+
+639
+00:44:51,110 --> 00:44:56,350
+قد لا تساهم في عملية التشخيص الجيني طبعا هذه
+
+640
+00:44:56,350 --> 00:45:01,250
+الفكرة ببساطة هذه البوايضة عند ال first polar body
+
+641
+00:45:01,250 --> 00:45:04,630
+موجود في ال aspiration needle و عند ال second
+
+642
+00:45:04,630 --> 00:45:08,650
+polar body و هذا ال first polar body لأن دائما هذه
+
+643
+00:45:08,650 --> 00:45:11,430
+البوايضة يكون ال first polar body عند الساعة 12
+
+644
+00:45:11,430 --> 00:45:15,910
+for exampleو ال second polar body على يمينه دائما
+
+645
+00:45:15,910 --> 00:45:19,130
+بكون على يمينه فبالتالي لما انت تعمل دخول بال
+
+646
+00:45:19,130 --> 00:45:22,970
+aspiration needle او aspiration pipet هتسحب في
+
+647
+00:45:22,970 --> 00:45:25,450
+البداية ال first polar body .. ال second polar
+
+648
+00:45:25,450 --> 00:45:29,980
+bodyولكن في البداية هيكون ال second polar body هنا
+
+649
+00:45:29,980 --> 00:45:33,660
+هتدخل بال aspiration tube شوية فبالتالي بتكون حركة
+
+650
+00:45:33,660 --> 00:45:38,340
+ال polar body هذا عن مكانه فبتسحب ال second polar
+
+651
+00:45:38,340 --> 00:45:41,800
+body بتدخله داخل ال aspiration tube وبعدين بتسحب
+
+652
+00:45:41,800 --> 00:45:45,080
+ال second polar body كما هو ال first وال second
+
+653
+00:45:45,080 --> 00:45:49,200
+بيكون سحتهم مع بعض خليني أشوف الفيديو اللي بتكلم
+
+654
+00:45:49,200 --> 00:45:53,280
+عن هذه العملية وبعدين نرجع للموضوع مرة أخرى
+
+655
+00:46:00,380 --> 00:46:03,620
+طبعا هنا هيتكلم عن ال assist hatching باستخدام ال
+
+656
+00:46:03,620 --> 00:46:07,520
+laser طبعا يحدد المناطق هيما بين الساعة 2 والساعة
+
+657
+00:46:07,520 --> 00:46:11,600
+3 هيعمل اطلاق لشعار ال laser في المناطق هذه
+
+658
+00:46:19,130 --> 00:46:22,930
+هو عنده زي حاجة تشبه القناص إلى حد ما زي شرط
+
+659
+00:46:22,930 --> 00:46:26,270
+القناص بتغطي في هذه المنطقة تشوف حدد ال depth لوين
+
+660
+00:46:26,270 --> 00:46:31,250
+نهايته هذه حدد و بعمل clicking على الذر كأنه بطلق
+
+661
+00:46:31,250 --> 00:46:35,410
+لل laser هنا بيكون حدد المكان مجرد ما ضغط على الذر
+
+662
+00:46:35,410 --> 00:46:39,030
+بيصير اطلاق لشعار ال laser بيكون معايره ل depth
+
+663
+00:46:39,030 --> 00:46:43,370
+معين بقوة معينة هذي ال Empyrenic stem cell في
+
+664
+00:46:43,370 --> 00:46:43,730
+الغالب
+
+665
+00:47:07,290 --> 00:47:10,870
+شوفش هنا كتب start firing لما ضغط على الذر هذا
+
+666
+00:47:10,870 --> 00:47:15,470
+الذر ده اسمها start firing يعني بداية إطلاق ال
+
+667
+00:47:15,470 --> 00:47:18,410
+laser فبطلقها ب depth معين في مكان معين بناء على
+
+668
+00:47:18,410 --> 00:47:23,540
+المنطقة اللي حدثأيضًا هنا بيقول يا كام holes بده
+
+669
+00:47:23,540 --> 00:47:26,720
+بده ال width بده ال size ده ال hole و كام hole بده
+
+670
+00:47:26,720 --> 00:47:29,720
+ستة سبعة تمانية بناء على حجم الخلية اللي بده
+
+671
+00:47:29,720 --> 00:47:34,080
+يسحبها طبعًا هنا بده يسحب ال embryo cells احنا
+
+672
+00:47:34,080 --> 00:47:36,560
+بنحكي على ال biopsy بنفس الطريقة ولكن هنا بده يسحب
+
+673
+00:47:36,560 --> 00:47:39,700
+ال embryo cells فبالتالي بيكون أعمق علشان يصل ال
+
+674
+00:47:39,700 --> 00:47:40,940
+embryo بشكل أسلوب
+
+675
+00:48:08,590 --> 00:48:12,370
+هكذا بيكون عمل assist hatching باستخدام ال laser
+
+676
+00:48:12,370 --> 00:48:17,350
+أخرج embryonic stem سل واحدة طبعا ال polar body
+
+677
+00:48:17,350 --> 00:48:20,910
+مهم جدا مهم جدا ال polar body علشان يكشف على
+
+678
+00:48:20,910 --> 00:48:24,110
+الأمراض الوراثية المتعلقة بال female بشكل أساسي
+
+679
+00:48:38,850 --> 00:48:42,930
+هذا بيقلل كمية ال contamination التي يمكن أن تحدث
+
+680
+00:48:42,930 --> 00:48:46,990
+فبالتالي من خلال تقليل عدد الخلال التي يمكن أن
+
+681
+00:48:46,990 --> 00:48:51,890
+تخرج مع ال polar body مع ال polar body هذا شكل أخر
+
+682
+00:48:51,890 --> 00:48:56,830
+من الأشكال الخاصة فيه طبعا هذه بدخل ب aspiration
+
+683
+00:48:56,830 --> 00:49:01,490
+needle سحب أو ثبت ال first polar body بعدين
+
+684
+00:49:01,490 --> 00:49:04,890
+بيسحبوا بهذا الشكل سحب ال second polar body بعدين
+
+685
+00:49:04,890 --> 00:49:08,570
+سحب ال first polar body طلع منهم و أضافهم في منطقة
+
+686
+00:49:08,960 --> 00:49:13,240
+خالية كدا سنكتفي بهذا القدر في هذه المحاضرة على
+
+687
+00:49:13,240 --> 00:49:16,640
+أمل أن نلتقي في محاضرة قادمة ان شاء الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Vk4A33MkSlQ_raw.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Vk4A33MkSlQ_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..26880fa511ff51fe1ed5f882e58b6f0da40f94a8
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Vk4A33MkSlQ_raw.srt
@@ -0,0 +1,2748 @@
+1
+00:00:00,670 --> 00:00:04,590
+بسم الله الرحمن الرحيم والصلاة والسلام على أفضل
+
+2
+00:00:04,590 --> 00:00:09,750
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا
+
+3
+00:00:09,750 --> 00:00:14,110
+الأعزاء أرجو من الله الكريم أن تكونوا جميعا بخير
+
+4
+00:00:14,110 --> 00:00:19,430
+وبصحة جيدة تكلمنا في المحاضرات السابقة عن أمور شتة
+
+5
+00:00:19,430 --> 00:00:25,430
+تتعلق بقضية التلقيح وعملية الحقن المجهري ومن أشهر
+
+6
+00:00:25,430 --> 00:00:29,820
+هذه المواضيع التي تحدثنا عنهاكيف تتكون الجميطات
+
+7
+00:00:29,820 --> 00:00:33,980
+عند ال male و ال female تحت عنوان spermatogenesis
+
+8
+00:00:33,980 --> 00:00:39,460
+و oogenesis كيف تنتقل هذه الجميطات من مكان التصنيع
+
+9
+00:00:39,460 --> 00:00:44,800
+إلى مكان التخزين ثم إلى مكان التطور والنضوج لكي
+
+10
+00:00:44,800 --> 00:00:49,500
+يمكن أن تستخدم ثم تحدثنا عن القالية التي يتم من
+
+11
+00:00:49,500 --> 00:00:53,240
+خلالها تحضير الأطواق الأطباق الخاصة بالحقن المجهري
+
+12
+00:00:53,240 --> 00:00:58,200
+تحت عنوان XY dish preparationثم تحدثنا عن عملية
+
+13
+00:00:58,200 --> 00:01:02,620
+الحقن المجهري وكيف تتم ومن خلال عملية التحدث عن
+
+14
+00:01:02,620 --> 00:01:05,760
+الحقن المجهري تحدثنا عن آلية التعامل مع ال
+
+15
+00:01:05,760 --> 00:01:09,060
+spermatozoa من خلال مصطلح سمناه sperm
+
+16
+00:01:09,060 --> 00:01:14,240
+immobilization spermatozoa ثم تحدثنا عن ال oocyte
+
+17
+00:01:14,240 --> 00:01:19,040
+preparation من خلال عملية ال denudationوهي عبارة
+
+18
+00:01:19,040 --> 00:01:23,720
+عن التخلص من الخلايا الذائدة المحيطة بالبويضات
+
+19
+00:01:23,720 --> 00:01:29,080
+الناضجة التي تصلح لعملية الحقن الآن تمت عملية
+
+20
+00:01:29,080 --> 00:01:34,320
+الحقن سوف نتحدث عن عدة أمور مختلفة لها بالعلاقة
+
+21
+00:01:34,320 --> 00:01:39,080
+بانقسام الخلايا الملقحة أو البويضات الملقحة وكيف
+
+22
+00:01:39,080 --> 00:01:43,420
+تنقسم هذه البويضات وماذا تسمى كل مرحلة من مراحل
+
+23
+00:01:43,420 --> 00:01:48,460
+الانقسام ثم كيف تنتقل البويضة الملقحةمن مكان
+
+24
+00:01:48,460 --> 00:01:52,220
+التلقيح الطبيعي وهو عبارة عن الـ Fallopian tube
+
+25
+00:01:52,220 --> 00:01:58,040
+حتى حدوث عملية implantation في بطانة الرحمة هذا ما
+
+26
+00:01:58,040 --> 00:02:02,440
+سوف نتحدث عنه في هذا الشيء من هذه المحاضرة ثم
+
+27
+00:02:02,440 --> 00:02:07,280
+ننتقل إلى موضوع جديد وهو كيف نحدد بعض الأمراض
+
+28
+00:02:07,280 --> 00:02:11,580
+الوراثية المتعلقة بالأجنة من خلال ما يُعرف اسم
+
+29
+00:02:11,580 --> 00:02:18,850
+Empyreobiosis أو polar body biopsyهذا ما سوف نتحدث
+
+30
+00:02:18,850 --> 00:02:23,670
+عنه في الـ Chapter رقم 6 After fertilization، بعد
+
+31
+00:02:23,670 --> 00:02:27,090
+عملية ال fertilization وهو إدخال single sperm في
+
+32
+00:02:27,090 --> 00:02:31,470
+mature oocyte تبدأ عملية اندماج النواذ ذكرية مع
+
+33
+00:02:31,470 --> 00:02:35,530
+النواذ أنثوية، مما يؤدي إلى تكوين خلية جديدة تسمى
+
+34
+00:02:35,530 --> 00:02:41,450
+الزيجوت فالزيجوت هي عبارة عن أول ناتج طبيعي لعملية
+
+35
+00:02:41,450 --> 00:02:45,840
+الحقن المجهريإلى العملية تكوين الزيجوت بيحدث
+
+36
+00:02:45,840 --> 00:02:50,360
+shifting لـmetabolic process و ال event اللي ممكن
+
+37
+00:02:50,360 --> 00:02:55,080
+تحدث في الخلية والبوايضة الملقحة مما يؤدي إلى
+
+38
+00:02:55,080 --> 00:03:00,060
+دخولها في عدة انقسامات للحصول على ال embryo الذي
+
+39
+00:03:00,060 --> 00:03:04,620
+سوف يحدث له عملية implantation في بطانة الرحم
+
+40
+00:03:04,620 --> 00:03:10,290
+ليكوّن a new babyخلال هذه الفترة وخلال هذه العملية
+
+41
+00:03:10,290 --> 00:03:14,730
+من لحظة التلقيح وتكون الـ Zygote حتى لحظة ال
+
+42
+00:03:14,730 --> 00:03:18,410
+implantation يبقى الجنين أو قبل لحظة ال
+
+43
+00:03:18,410 --> 00:03:22,270
+implantation بشيء بسيط يبقى الجنين والخلايا
+
+44
+00:03:22,270 --> 00:03:26,190
+الجنينية محاطة بغلاف واحد وهو عبارة عن الـ
+
+45
+00:03:26,190 --> 00:03:31,410
+Zoonopelucida و لا يتحطم هذا الغلاف يعني ما بيصير
+
+46
+00:03:31,410 --> 00:03:35,210
+the structure أو breakdown for Zoonopelucida حتى
+
+47
+00:03:35,210 --> 00:03:39,630
+لحظة ال implantationبمجرد أن يصل الجنين لعدد معين
+
+48
+00:03:39,630 --> 00:03:44,310
+من القسمات و الخلايا و يصل للمكان المعدله لكي يحدث
+
+49
+00:03:44,310 --> 00:03:47,270
+له عملية انغراض في بطانة الرحل تبدأ الـ
+
+50
+00:03:47,270 --> 00:03:50,670
+Zoonopelucida في التهتق و تبدأ الـ Zoonopelucida
+
+51
+00:03:50,670 --> 00:03:55,910
+في التكسر و التحطم لكي تسمح بوجود منفذ لهذا الجنين
+
+52
+00:03:55,910 --> 00:04:00,930
+لحدوث اتصال مباشر ما بينه و ما بين بطانة الرحل
+
+53
+00:04:00,930 --> 00:04:04,170
+الموجودة في المنطقة التي يحدث لها عملية ال
+
+54
+00:04:04,170 --> 00:04:10,040
+implantationالى حد ما حوالي 6 ايام بعد ذلك
+
+55
+00:04:10,040 --> 00:04:15,380
+الانبريو شد ذونا باليوسيدا واتشت اليوتران لين يعني
+
+56
+00:04:15,380 --> 00:04:20,060
+بعد ست أيام من عملية الحقل او بعد ست أيام بالضبط
+
+57
+00:04:20,060 --> 00:04:26,860
+يبدأ الانبريو بالخروج من الذونا باليوسيدا الاتفاق
+
+58
+00:04:26,860 --> 00:04:31,140
+بين البلاسنتل والماترة التي أدت لإنقاذ الوحوسيت
+
+59
+00:04:31,140 --> 00:04:35,400
+لتخزين كمية يوكساكthat needed during development
+
+60
+00:04:35,400 --> 00:04:39,440
+therefore the eggs of mammalian are very small هذه
+
+61
+00:04:39,440 --> 00:04:44,920
+الفقرة بتوضع سؤال مهم جدا لو أنا قرنت البوايضة
+
+62
+00:04:44,920 --> 00:04:49,300
+الخاصة بالفديات زي ال human مع البوايضة الخاصة بال
+
+63
+00:04:49,300 --> 00:04:54,180
+animal بالطيور مثلا في بعض الحيوانات بتبيض على
+
+64
+00:04:54,180 --> 00:05:00,260
+سبيل المثال فيه فبالتالي لو أنا قرنت حجم البوايضة
+
+65
+00:05:00,260 --> 00:05:04,270
+مع حجم البوايضة الأخرىهلاجي حجم البوايضة الخاصة
+
+66
+00:05:04,270 --> 00:05:08,190
+بليه human صغيرة جدا مقارنة مع حجم البوايضة الخاصة
+
+67
+00:05:08,190 --> 00:05:14,490
+ببعض أنواع من الطيور أو بعض أنواع من الحيوانات
+
+68
+00:05:14,490 --> 00:05:19,150
+التي الطبيب فالسبب في هذا الموضوع يرجع إلى وجود
+
+69
+00:05:19,150 --> 00:05:23,310
+كمية كبيرة جدا من ال yolk sac في عفوا كمية كبيرة
+
+70
+00:05:23,310 --> 00:05:28,750
+جدا من ال yolk داخل ال yolk sac تستخدمها البوايضة
+
+71
+00:05:28,750 --> 00:05:34,160
+ذات الحجم الكبير لعملية التخذيةوالنموك للحصول على
+
+72
+00:05:34,160 --> 00:05:38,140
+جنين طبيعي وجنين كامل النمو بينما في ال human
+
+73
+00:05:38,140 --> 00:05:43,220
+البوايضة الملقحة تتحول إلى embryo ال embryo ينغمس
+
+74
+00:05:43,220 --> 00:05:47,100
+في بطانة الرحم الخاصة بالأم مما يسمح له بتكوين
+
+75
+00:05:47,100 --> 00:05:51,360
+structure بنسميه placenta التي تصبح فيما بعد مصدر
+
+76
+00:05:51,360 --> 00:05:55,680
+للغذاء مصدر للغذاء فلا داعي ولا حاجة للبوايضة
+
+77
+00:05:55,680 --> 00:05:59,880
+الخاصة بال human ان تتغذى و تتخزن تتغذى نفسه بنفسه
+
+78
+00:05:59,880 --> 00:06:04,220
+او تتخزن كمية كبيرة جدامن اليوك في داخلها فبالتالي
+
+79
+00:06:04,220 --> 00:06:09,360
+الحجم يبقى صغير إذا كبر الحجم من صغره يعتمد على هل
+
+80
+00:06:09,360 --> 00:06:12,960
+البويضة بعد الطلقية سوف تغذي نفسها من نفسها أو
+
+81
+00:06:12,960 --> 00:06:16,160
+تعتمد على مصدر آخر إذا تغذي نفسها من نفسها زي
+
+82
+00:06:16,160 --> 00:06:21,400
+البويضات بتاعة القيور مثلا فبالتالي لازم تكون كمية
+
+83
+00:06:21,400 --> 00:06:25,580
+كبيرة جدا من اليوك مخزنة بداخل البويضة حتى تسمح
+
+84
+00:06:25,580 --> 00:06:30,160
+لها بعملية النمو والانقسامMammalian cleavage is a
+
+85
+00:06:30,160 --> 00:06:34,900
+prolonged process that typically takes a large
+
+86
+00:06:34,900 --> 00:06:39,680
+amount of time and requires to transport the early
+
+87
+00:06:39,680 --> 00:06:44,340
+embryo form its site of fertilization to the site
+
+88
+00:06:44,340 --> 00:06:48,320
+of implantation بمعنى آخر أن عملية الـ cleavage
+
+89
+00:06:48,320 --> 00:06:51,740
+الخاصة بالبويضة الملقح الخاصة بالماماليا الفديات
+
+90
+00:06:51,740 --> 00:06:55,160
+تأخذ فترة زمنية طويلة جدا ما بين لحظة ال
+
+91
+00:06:55,160 --> 00:06:59,980
+fertilizationمرورا بالانقسامات المتتالية ووصولا
+
+92
+00:06:59,980 --> 00:07:03,900
+إلى منطقة الـ Implantation في بيطانة الرحم الحنعرف
+
+93
+00:07:03,900 --> 00:07:07,720
+جديش بتاخد فترة زمنية ال development procedure at
+
+94
+00:07:07,720 --> 00:07:11,280
+the rate of roughly one cleavage division per one
+
+95
+00:07:11,280 --> 00:07:15,500
+day يعني عملية الانقسام في البوايدة الملقحة في أول
+
+96
+00:07:15,500 --> 00:07:19,400
+يومين بيكون ثابت انقسام واحد كل يومبعد كده بعد
+
+97
+00:07:19,400 --> 00:07:22,880
+اليوم الأول والتاني بشكل أساسي تختلف معدّى
+
+98
+00:07:22,880 --> 00:07:27,180
+الإنقسامات فتصبح متسارعة عشان تصل للعدد المطموعة
+
+99
+00:07:27,180 --> 00:07:33,620
+من الخلايا بعد اليوم التاني أو بعد ما تكوين two
+
+100
+00:07:33,620 --> 00:07:37,500
+cells خلينا نسميها بشكل أوضح وشكل أدق بيصير في
+
+101
+00:07:37,500 --> 00:07:40,960
+عندي نوع من أنواع التزامن في الإنقسامات بمعنى أخر
+
+102
+00:07:40,960 --> 00:07:44,160
+أن الخلية في اليوم الأول بتاعة خليتين فبسمّي
+
+103
+00:07:44,160 --> 00:07:49,540
+الخليتينالـ Plastomere بعد كده الـ Plastomere
+
+104
+00:07:49,540 --> 00:07:54,360
+هتنقسم إلى تلات خلائي والتلات و كذا هينقسموا يعني
+
+105
+00:07:54,360 --> 00:07:56,560
+بيصير عندى اتنين الاتنين بيصيروا تلاتة بعدين
+
+106
+00:07:56,560 --> 00:07:58,740
+بيصيروا اربعة الاربعة بيصيروا تمانية تمانية
+
+107
+00:07:58,740 --> 00:08:02,840
+بيصيروا ستاشر لما نتصل لمرحلة خلية واحدة تحتوي
+
+108
+00:08:02,840 --> 00:08:07,400
+بداخلها على ست عشر خلية بنسمي ال whole structure
+
+109
+00:08:07,400 --> 00:08:11,560
+موريلا بنسمي ال whole structure موريلا وهذا الكلام
+
+110
+00:08:11,560 --> 00:08:16,320
+خدناه في المحاضرة السابقةالخلايا الموجودة بداخل
+
+111
+00:08:16,320 --> 00:08:20,000
+الخلية الأم أو البويضة الأم إذا كانت تحتوي على
+
+112
+00:08:20,000 --> 00:08:24,540
+تمانية لستة عشر stage the embryo of placental
+
+113
+00:08:24,540 --> 00:08:27,360
+mammalian enter in the phase called competition
+
+114
+00:08:27,360 --> 00:08:31,920
+يعني بمجرد ما تصل عدد الخلايا في الداخل اللي
+
+115
+00:08:31,920 --> 00:08:36,860
+سمناها embryonic stem cell تمان خلايا وتبدأ تتزايد
+
+116
+00:08:36,860 --> 00:08:40,670
+لتصل إلى ستة عشر خلية عشان تعطين الموريلابصير هذه
+
+117
+00:08:40,670 --> 00:08:43,570
+المرحلة بنسميها competition stage شو معنى
+
+118
+00:08:43,570 --> 00:08:45,450
+competition stage؟ what's the meaning of
+
+119
+00:08:45,450 --> 00:08:47,690
+competition stage؟ what do you know about the
+
+120
+00:08:47,690 --> 00:08:50,730
+competition stage؟ ال competition stage ببساطة جدا
+
+121
+00:08:50,730 --> 00:08:54,150
+هي مرحلة يتم فيها تداخل الخلايا مع بعض على بعض
+
+122
+00:08:54,150 --> 00:08:59,930
+لدرجة انك مابتقدر تشوف حد كل خلية عن الأخرى انت
+
+123
+00:08:59,930 --> 00:09:04,650
+بتلاقيهم كجملة واحدة كتلة واحدة مدمجين مع بعض ومع
+
+124
+00:09:04,650 --> 00:09:09,490
+بعض مافيحدود ما بين الخلايا مافي خلية تقول والله
+
+125
+00:09:09,490 --> 00:09:13,770
+أنا هذا ال outer layer الخاص بيها بتلاقيهم نوع من
+
+126
+00:09:13,770 --> 00:09:17,470
+أنواع الاندماج this process which occur
+
+127
+00:09:17,470 --> 00:09:21,250
+approximately four days after fertilization وهذه
+
+128
+00:09:21,250 --> 00:09:26,590
+العملية بنسميها cavitation في عملية ال competition
+
+129
+00:09:26,590 --> 00:09:31,980
+بشكل أساسي بيصير اندماج الخلايا مع بعضها البعضمافي
+
+130
+00:09:31,980 --> 00:09:36,260
+عندى outer layer للخلايا وحدود الخلايا بتصير عندى
+
+131
+00:09:36,260 --> 00:09:39,840
+junction بين بعض البعض تحت مصطلح tied adhere
+
+132
+00:09:39,840 --> 00:09:44,180
+through the gap and tied junction and lose their
+
+133
+00:09:44,180 --> 00:09:48,820
+individual identity individual line win view from
+
+134
+00:09:48,820 --> 00:09:51,480
+the surface يعني الخلايا بتندمش مع بعض البعض
+
+135
+00:09:51,480 --> 00:09:55,640
+الخلايا تداخل مع بعض البعض مافي outer layer أو
+
+136
+00:09:55,640 --> 00:10:00,100
+outline لكل خلية مافي border لكل خليةبتلاقي
+
+137
+00:10:00,100 --> 00:10:03,300
+الخلايا اندمجت مع بعض البعض واتصلت مع بعض البعض
+
+138
+00:10:03,300 --> 00:10:08,680
+طبعا اندماج الخلايا وانغماسها مع بعض البعض المرحلة
+
+139
+00:10:08,680 --> 00:10:13,000
+كلها بنسميها competition as phase بينما ال process
+
+140
+00:10:13,000 --> 00:10:18,900
+هذه بنسميها cavitation وبتصير في اليوم الرابعمن
+
+141
+00:10:18,900 --> 00:10:22,480
+بعد عملية ال fertilization at this stage المقصود
+
+142
+00:10:22,480 --> 00:10:26,580
+فيه ال competition stage the embryo as whole is no
+
+143
+00:10:26,580 --> 00:10:30,720
+plastocyst لما بعد يصير عندي أربع أيام و يصير
+
+144
+00:10:30,720 --> 00:10:34,380
+الاندماج المتميز بين الخلايا يعني تصير مرحلة ال
+
+145
+00:10:34,380 --> 00:10:40,520
+cavitation بسمي ال structure ككل بسميه plastocyst
+
+146
+00:10:40,520 --> 00:10:45,500
+بسميه plastocyst خلاية أو صورة بتوضح الكلام هذا في
+
+147
+00:10:45,500 --> 00:10:49,890
+عندي هناوهي عبارة عن بويضة لقحت أعطتني في اليوم
+
+148
+00:10:49,890 --> 00:10:53,950
+الأول خليتين كانت one cells سميتها as I got بعدين
+
+149
+00:10:53,950 --> 00:10:56,870
+اتقسمت التلت ل two cells هذا في اليوم الأول في
+
+150
+00:10:56,870 --> 00:10:59,730
+اليوم التاني أدتني أربع خلايا كل خلية بتسميها plus
+
+151
+00:10:59,730 --> 00:11:04,110
+to minus في اليوم التاني ونص جريبا علشان نتصل
+
+152
+00:11:04,110 --> 00:11:08,030
+اليوم التالت وهي 8 من 8 ل 16 خلية في اليوم التالت
+
+153
+00:11:08,030 --> 00:11:12,410
+16 خلية اللي بتسميها morela في اليوم الرابع تصير
+
+154
+00:11:12,410 --> 00:11:17,240
+58 خلية بتسميها plus to sixthفي اليوم الخامس
+
+155
+00:11:17,240 --> 00:11:21,820
+بتنقسم إلى 107 خلية بنسميها Plastocyst أيضًا إذا
+
+156
+00:11:21,820 --> 00:11:27,280
+الموريلا بتظهر في اليوم التالت من الخسام وتحتوي
+
+157
+00:11:27,280 --> 00:11:32,940
+على أكتر من 8 خلايا كحد أدنى وحد أقصى 16 خلية
+
+158
+00:11:32,940 --> 00:11:37,640
+Plastocyst بتزيد عن 16 خلية وكل هذه المراحل بتكون
+
+159
+00:11:37,640 --> 00:11:40,700
+مازالت محاطة بالـ Zoonapelucida
+
+160
+00:11:42,660 --> 00:11:45,860
+At the beginning of cleavage, the zona is still in
+
+161
+00:11:45,860 --> 00:11:52,300
+case or in covering the
+
+162
+00:11:52,300 --> 00:11:56,120
+cell plus الـ cell المقصود فيها الخلايا الداخلية
+
+163
+00:11:56,120 --> 00:11:58,760
+ال embryonic stem cell يعني ال embryonic stem cell
+
+164
+00:11:58,760 --> 00:12:01,420
+ما ذالت ضمن محفظة واحدة اللي هي ال zona pellucida
+
+165
+00:12:01,420 --> 00:12:04,740
+و في الخارج يحيط بيها طبقة رقيقة من ال corona
+
+166
+00:12:04,740 --> 00:12:08,920
+radiata ال corona radiata تبقى كما هي حتى اليوم
+
+167
+00:12:08,920 --> 00:12:12,670
+الثانيبعد اليوم الثاني من عملية الإنقسامات تبدأ
+
+168
+00:12:12,670 --> 00:12:17,970
+بالاختفاء تدريجي رغم إن ال Corona Radiata منها
+
+169
+00:12:17,970 --> 00:12:21,310
+removing بالـdenodation ولكن ما بنقدر نعمل
+
+170
+00:12:21,310 --> 00:12:24,530
+removing completely بلقى جزء منها ما زال موجود
+
+171
+00:12:24,530 --> 00:12:28,740
+الـZoonableucida remained intactHowever, until the
+
+172
+00:12:28,740 --> 00:12:31,140
+embryo arrives to the uterus
+
+173
+00:12:40,420 --> 00:12:43,160
+وخدوا بالكوا مهم جدا .. هنعرف كمان شوية شو هي
+
+174
+00:12:43,160 --> 00:12:46,000
+أهمية الـ Zoonopathy ده مهم جدا الـ Zoonopathy ده
+
+175
+00:12:46,000 --> 00:12:51,020
+تبقى عشان مايصيرش تفتت للخلايا ويصير تفرق للخلايا
+
+176
+00:12:51,020 --> 00:12:54,980
+وبالتالي أفقد الجنين لأنه خلال عملية انتقال البيضة
+
+177
+00:12:54,980 --> 00:12:58,800
+المخصبة بحكي بشكل طبيعي من قناة فلوف إلى الرحم
+
+178
+00:12:58,800 --> 00:13:04,300
+بتبرم بعويقات كثيرة أقلها حركة السيليا فتصور لو أن
+
+179
+00:13:04,300 --> 00:13:07,980
+هذه الخلايا الـ Empyrenic Stem Cellاللي مش موجود
+
+180
+00:13:07,980 --> 00:13:11,860
+حولها الزنباليسيدا، هيصيرها تفتت و تفرق، بالتالي،
+
+181
+00:13:11,860 --> 00:13:15,680
+هيصير المحصلة انهائية Zero مافي عند الـ embryo
+
+182
+00:13:15,680 --> 00:13:19,340
+completely embryo الـ embryo تبقى في جزء الانبولار
+
+183
+00:13:19,340 --> 00:13:24,200
+من اليوتران تيوب تلت أيام، يعني ببدأ في منطقة
+
+184
+00:13:24,200 --> 00:13:27,840
+الانبولار الخاصة بالفلوبيان تيوب تلت أيام، يعني
+
+185
+00:13:27,840 --> 00:13:31,740
+البوايدة المخصبة تجلس في فلوبيان تيوب، وهي المرحلة
+
+186
+00:13:31,740 --> 00:13:34,980
+اللي هتنتقل منها، المسافة اللي هتقطعها، حوالي تلت
+
+187
+00:13:34,980 --> 00:13:39,120
+أيامIt then crossed the isthmus portion of the
+
+188
+00:13:39,120 --> 00:13:42,180
+tube in the little of eight hours يعني بوايدة
+
+189
+00:13:42,180 --> 00:13:45,160
+خُصبت في الطولة الأول الأعلى من ال fallopian tube،
+
+190
+00:13:45,160 --> 00:13:49,140
+هذا في الوضع الطبيعي، هتستمر و هتتدهرج لمدة زمانية
+
+191
+00:13:49,140 --> 00:13:52,840
+تقدر بتلت أيام، علشان تقطع طول ال fallopian tube
+
+192
+00:13:53,340 --> 00:13:56,560
+هتصل إلى منطقة المضيق وهو المنطقة اللتي تفصل
+
+193
+00:13:56,560 --> 00:13:59,700
+fallopian tube عن بداية الرحم واللي سميتها في ال
+
+194
+00:13:59,700 --> 00:14:04,020
+chapter الأول isthmus عشان تخترق ال isthmus و تعمل
+
+195
+00:14:04,020 --> 00:14:07,360
+scabbing لل isthmus أو entering لل isthmus تاخد
+
+196
+00:14:07,360 --> 00:14:11,780
+فقط 8 ساعات Under the influence of progesterone
+
+197
+00:14:11,780 --> 00:14:16,480
+neutral tube junction relaxation contraction
+
+198
+00:14:16,480 --> 00:14:20,720
+relaxation those allow the embryo to enter the
+
+199
+00:14:20,720 --> 00:14:23,860
+uterine cavityتحت تأثير الـ Progesterone الذي
+
+200
+00:14:23,860 --> 00:14:27,960
+يُفرز بشكل مستمر تحت تأثير انقباض وارتخاء العضلات
+
+201
+00:14:27,960 --> 00:14:32,840
+الخاصة بالرحم والأنابيب المتعلقة بالجهاز الـ
+
+202
+00:14:32,840 --> 00:14:38,280
+genital الـ reproductive system يسمح بدخول ال
+
+203
+00:14:38,280 --> 00:14:44,680
+embryo إلى الرحم، طالما دخل الرحم، إذن هيتكون معدل
+
+204
+00:14:44,680 --> 00:14:49,750
+عملية ال implantationCouples of day من ستة لات ستة
+
+205
+00:14:49,750 --> 00:14:53,110
+تقيد day after fertilization the embryo implanted
+
+206
+00:14:53,110 --> 00:14:56,150
+in the mid portion of the posterior wall of the
+
+207
+00:14:56,150 --> 00:15:01,310
+uterus يعني بعد حوالي ست أيام على الأقل إلى تلت
+
+208
+00:15:01,310 --> 00:15:05,110
+أيام على الأكثر من عملية ال fertilization المفروض
+
+209
+00:15:05,110 --> 00:15:10,250
+المفروض يكون الجنين قطع كل المسافة الخاصة بال
+
+210
+00:15:10,250 --> 00:15:14,490
+Fallopian tube وقطع الإزمس ووصل لمنطقة معينة عشان
+
+211
+00:15:14,490 --> 00:15:18,440
+يصيله implantation فيهبطن في الرحم وفي جدار الرحم
+
+212
+00:15:18,440 --> 00:15:22,500
+وفي المنطقة بيسموها بالضبط middle portion of
+
+213
+00:15:22,500 --> 00:15:27,120
+posterior wall of the uterus يعني لو صارت طلقاح
+
+214
+00:15:27,120 --> 00:15:34,040
+يوم 13 هتحسب الزوجة 13 14 15 16 17 18 19 20 في
+
+215
+00:15:34,040 --> 00:15:37,960
+اليوم ال 20 المفروض الجنين يكون صارله implantation
+
+216
+00:15:37,960 --> 00:15:41,760
+هذا الوضع الطبيعي الوضع الطبيعي علشان كده معظم
+
+217
+00:15:41,760 --> 00:15:45,970
+المراكز اللي بتعمل حق مجهريبتطلج الجنين في اليوم
+
+218
+00:15:45,970 --> 00:15:49,050
+بعد اليوم التالت يا إما الرابع، يا إما الخامس، يا
+
+219
+00:15:49,050 --> 00:15:53,610
+إما السادس علشان يحاكي الوضع الطبيعي during this
+
+220
+00:15:53,610 --> 00:15:57,330
+time خلال هذه الأيام، الـ6 إلى الـ8 أيام بعد عملية
+
+221
+00:15:57,330 --> 00:16:00,150
+ال fertilization الـZoona Pellucida بيصير فيها
+
+222
+00:16:00,150 --> 00:16:04,690
+تغير في تركيبها علشان تلائم المرحلة الجديدة تغير
+
+223
+00:16:04,690 --> 00:16:10,650
+في تركيبها تبدأ يصير فيها تغير علشان تبدأ يصيلها
+
+224
+00:16:10,650 --> 00:16:14,940
+عملية hatching شو يعني hatching؟ يعني openingطبعا
+
+225
+00:16:14,940 --> 00:16:18,580
+اتروا contribution from the blastomera and the
+
+226
+00:16:18,580 --> 00:16:20,900
+maternal reproductive tissue and this change
+
+227
+00:16:20,900 --> 00:16:24,120
+facilitated the transport and differentiation of
+
+228
+00:16:24,120 --> 00:16:26,560
+the embryo هذه مهمة جدا التغييرات اللي بتصير في
+
+229
+00:16:26,560 --> 00:16:29,120
+الزونا بليوسيدا لأن المفروض الزونا بليوسيدا ما
+
+230
+00:16:29,120 --> 00:16:33,440
+تبقى rigid ما تبقى hard لفترة زمنية طويلة مهمة في
+
+231
+00:16:33,440 --> 00:16:38,640
+مرحلة الانتقال ولكن بمجرد حدوث ووصول إلى مرحلة ال
+
+232
+00:16:38,640 --> 00:16:42,950
+implantation لازم يصير فيها changingأو يصير فيها
+
+233
+00:16:42,950 --> 00:16:49,310
+thinning علشان تبدأ وتسمح لل embryo بالخروج طبعا
+
+234
+00:16:49,310 --> 00:16:54,510
+بعد ما يصل ال embryo لبطانة الرحم أو الرحم أو
+
+235
+00:16:54,510 --> 00:16:57,590
+تجويف الرحم تبدأ ال zona pellucida بتعمل hatching
+
+236
+00:16:57,590 --> 00:17:01,610
+أو تعمل removing أو تعمل opening تمهيد لل
+
+237
+00:17:01,610 --> 00:17:06,110
+implantation وعملية وجود ثقوب وفتح ثقوب في zona
+
+238
+00:17:06,110 --> 00:17:10,270
+pellucida بنسمي هذه العملية hatching أو بنسميها
+
+239
+00:17:10,270 --> 00:17:16,750
+plastocyst hatchingHatching يعني poor formation
+
+240
+00:17:16,750 --> 00:17:21,150
+متى بيبدأ الهاتشينج؟ بعد تمان أيام من عملية
+
+241
+00:17:21,150 --> 00:17:26,810
+التلقيح و ذلك بمجرد وصول الويضة الملقح اللي صارت
+
+242
+00:17:26,810 --> 00:17:30,490
+embryo إلى تجويف الرحمة a small region of the
+
+243
+00:17:30,490 --> 00:17:33,150
+navel used a huge one directly over the inner cell
+
+244
+00:17:33,150 --> 00:17:37,250
+mass in the mammalian for example, the sole and
+
+245
+00:17:37,250 --> 00:17:42,240
+the plosocyst embeddedfrom the hole يعني بمعنى آخر
+
+246
+00:17:42,240 --> 00:17:45,400
+إن الـ zoonapalus ده كمية كبيرة ومناطق معينة من
+
+247
+00:17:45,400 --> 00:17:50,280
+الـ zoonapalus ده تتحطم تتفتح هذا يسمح بيصيرها
+
+248
+00:17:50,280 --> 00:17:54,540
+dissolving بمعنى آخر يسمح بخروج الـ plastocyst و
+
+249
+00:17:54,540 --> 00:18:00,040
+يحدث لها direct contact مع البطانة الرحم مما يمهد
+
+250
+00:18:00,040 --> 00:18:04,060
+لعملية ال implantation يعني كأنه بيصير hole أو
+
+251
+00:18:04,060 --> 00:18:10,040
+pores في الرحم في الرحم بيصير عندي حاجة بتسميهاThe
+
+252
+00:18:10,040 --> 00:18:13,260
+trophoectoderm projections then contact with the
+
+253
+00:18:13,260 --> 00:18:16,180
+endomaterium epithelium cell as the process of
+
+254
+00:18:16,180 --> 00:18:19,580
+implantation الـTrophoectoderm هي عبارة عن نوع من
+
+255
+00:18:19,580 --> 00:18:22,260
+أنواع الخلايا الموجودة في الـembryo، إذا بتذكروا
+
+256
+00:18:22,260 --> 00:18:26,600
+في المحاضرة السابقة الـTrophoectoderm وIntoderm
+
+257
+00:18:26,600 --> 00:18:30,860
+وMesoderm هذا الـTrophoectoderm هي التي تبدأ كبروز
+
+258
+00:18:30,860 --> 00:18:34,420
+تتحد مع بطانط الرحم، علشان تبدأ تمهيد
+
+259
+00:18:34,420 --> 00:18:37,800
+للـimplantationفي enzymatic activity around the
+
+260
+00:18:37,800 --> 00:18:41,400
+enter trophoplast soon beginning to dissolve the
+
+261
+00:18:41,400 --> 00:18:44,180
+rest of the zona pellucida بعد ما تبدأ ال
+
+262
+00:18:44,180 --> 00:18:48,060
+projection تظهر و تصير contact مع ال endometrium
+
+263
+00:18:48,060 --> 00:18:52,080
+of the epithelium cell في بعض التغيرات الإنزيمية
+
+264
+00:18:52,080 --> 00:18:56,560
+والنشاطات الإنزيمية التي تبدأ في الحدوث مما يمهد
+
+265
+00:18:56,560 --> 00:19:00,980
+إلى اختفاء ما تبقى من الzona pellucida وتحلولها
+
+266
+00:19:00,980 --> 00:19:07,270
+هذا بالنسبة إلى عملية الحطنوكيف تتم عملية انتقال
+
+267
+00:19:07,270 --> 00:19:13,290
+البويضة بعد عملية التلقيح الطبيعي في الصورة
+
+268
+00:19:13,290 --> 00:19:16,130
+التالية بتوضح عند البويضة صار لها عملية
+
+269
+00:19:16,130 --> 00:19:20,130
+implantation اعفوا صار لها عملية ovulation ثم في
+
+270
+00:19:20,130 --> 00:19:23,830
+النهاية implantation ال ovulation للبويضة البويضة
+
+271
+00:19:23,830 --> 00:19:28,550
+صارت بويضة طبعا ماضجة في المبيض صار لها ovulation
+
+272
+00:19:28,550 --> 00:19:32,030
+في صار contact بين ال male و ال female صار عند ال
+
+273
+00:19:32,030 --> 00:19:36,630
+fertilizationالفيرتاليزيشن صار عندى 2 nuclei فداني
+
+274
+00:19:36,630 --> 00:19:41,610
+الزيجوت تطورت من مادة إلى تكوين 1 cell بعدين 2
+
+275
+00:19:41,610 --> 00:19:46,730
+cell بعدين 4 cell بعدين 8 cell بعدين موريلا هي من
+
+276
+00:19:46,730 --> 00:19:51,090
+أكتر من 8 خلايا إلى 16 خلية بعدين ال plasticest
+
+277
+00:19:51,090 --> 00:19:56,350
+بعدين بعد 8 أيام صار عملية ال implantation في جدار
+
+278
+00:19:56,350 --> 00:20:02,610
+الرحم في جدار الرحم هذه عبارة عن الصورالتي تحدد أو
+
+279
+00:20:02,610 --> 00:20:06,090
+الصورة التي تحدد مراحل عملية انتقال البويضة بعد
+
+280
+00:20:06,090 --> 00:20:09,270
+التخصيف من الـ fallopian tube إلى بيطانة الرحل
+
+281
+00:20:09,270 --> 00:20:13,450
+طبعا الصورة السفلية بتحدد كيف بيصير عندي عملية
+
+282
+00:20:13,450 --> 00:20:18,530
+removing لل half of number of chromosome من أجل
+
+283
+00:20:18,530 --> 00:20:23,110
+ظهور ال first و second polar body لأنه قلنا أن أول
+
+284
+00:20:23,110 --> 00:20:27,370
+علامة من عمليات نجاح الحقن المجهريأو عمليات
+
+285
+00:20:27,370 --> 00:20:32,190
+التلقيح بشكل عام هي ظهور الـ second polar bond طيب
+
+286
+00:20:32,190 --> 00:20:35,810
+الـ Zoonapolysida حكينا عنها بكمية كبيرة جدا ما هي
+
+287
+00:20:35,810 --> 00:20:39,850
+أهميتها؟ الـ Zoonapolysida لها أهمية كبيرة جدا شو
+
+288
+00:20:39,850 --> 00:20:43,870
+هي أهميتها؟ لماذا تستخدم؟ وكيف تستخدم؟ الـ
+
+289
+00:20:43,870 --> 00:20:47,670
+Zoonapolysida هي عبارة عن طبقة رقيقة في البداية
+
+290
+00:20:47,670 --> 00:20:51,770
+تحيط بالبوايدة لتحمل بوايدة وتسهل عملية ال
+
+291
+00:20:51,770 --> 00:20:55,480
+connection ما بين البوايدةوالوسط الخارجي أو المحيط
+
+292
+00:20:55,480 --> 00:20:59,700
+الخارجي أو البيئة الخارجية كما أسلفنا سابقًا هل
+
+293
+00:20:59,700 --> 00:21:03,620
+لها عوامل أخرى وظائف أخرى؟ أكيد لها وظائف أخرى
+
+294
+00:21:03,620 --> 00:21:06,720
+وظائف شتة الـ Zoonopelucida بنرمز إلى بالـ ZB
+
+295
+00:21:06,720 --> 00:21:10,300
+وبتتكون في الغالب من sulphide glycoprotein يعني
+
+296
+00:21:10,300 --> 00:21:14,440
+هتبارع عن ال protein plus carbohydrate الـ
+
+297
+00:21:14,440 --> 00:21:16,720
+Zoonopelucida بتلعب دور كبير جدًا في عملية ال
+
+298
+00:21:16,720 --> 00:21:19,940
+protection بتلعب دور كبير جدًا في عملية ال embryo
+
+299
+00:21:19,940 --> 00:21:25,700
+developmentبتلعب دور كبير جدا في عملية step by
+
+300
+00:21:25,700 --> 00:21:29,000
+step أو point by point أول حاجة الـ function
+
+301
+00:21:29,000 --> 00:21:32,080
+الأساسية للـ Zoonopelucida بعد ال fertilization
+
+302
+00:21:32,080 --> 00:21:35,860
+إنها بتعمل protection للـ embryo وبتعمل إليه
+
+303
+00:21:35,860 --> 00:21:39,480
+maintenance of its integrity مهم جدا لأن الـ
+
+304
+00:21:39,480 --> 00:21:44,420
+Zoonopelucida إنها بتحمل الجنين بتحمل خلايا
+
+305
+00:21:44,420 --> 00:21:48,240
+الجنينية ما بتخلي الخلايا الجنينية متفرقة مبعثرة
+
+306
+00:21:48,240 --> 00:21:53,190
+فبالتالي تبقىالزونابلوسيدا أشهر وظيفة لها بعد ال
+
+307
+00:21:53,190 --> 00:21:56,190
+fertilization هي حماية الجنين والمحافظة على
+
+308
+00:21:56,190 --> 00:22:01,170
+التراكيب الداخلية الخاصة فيه الزونابلوسيدا هي التي
+
+309
+00:22:01,170 --> 00:22:05,250
+تسمح بعملية ال maturation لل oocyte في البداية
+
+310
+00:22:05,250 --> 00:22:12,160
+الزونابلوسيدا تعتبر عامل مهم جدا حيث تسمحليتمام
+
+311
+00:22:12,160 --> 00:22:15,360
+عملية الـ Fertilization من خلال وجود Receptor خاصة
+
+312
+00:22:15,360 --> 00:22:18,140
+بالـ spermatozoa هذه الـ Receptor موجودة في
+
+313
+00:22:18,140 --> 00:22:20,900
+الزونابليوس ده الـ three لأنه جُلنا الزونابليوس ده
+
+314
+00:22:20,900 --> 00:22:24,540
+أكثر من طبقة الـ zoonabelius ده هي التي تسمح
+
+315
+00:22:24,540 --> 00:22:28,260
+بعملية الـ Acrosome reaction يعني عملية ال
+
+316
+00:22:28,260 --> 00:22:32,260
+fertilization مش sperm ارتبط ببوايضة فقط لأ sperm
+
+317
+00:22:32,260 --> 00:22:36,120
+وصلت للبوايضة ارتبط بال Receptor نشطت البوايضة ال
+
+318
+00:22:36,120 --> 00:22:39,750
+Acrosome reaction علشان يساعد على الاختراقفمهم جدا
+
+319
+00:22:39,750 --> 00:22:43,030
+after fertilization the modified zona pellucida
+
+320
+00:22:43,030 --> 00:22:47,090
+prevent any additional sperm from the arrival to
+
+321
+00:22:47,090 --> 00:22:52,030
+the zygote or another penetration يعني شفنا
+
+322
+00:22:52,030 --> 00:22:55,190
+وظيفتها قبل ال fertilization وشفنا وظيفتها بعد ال
+
+323
+00:22:55,190 --> 00:22:58,210
+fertilization قبل ال fertilization حماية البويضة
+
+324
+00:22:58,210 --> 00:23:03,950
+تطوير البويضة تسهيل عملية ال fertilization كمان
+
+325
+00:23:03,950 --> 00:23:07,450
+تنشيط الأكروزمراكتش هذا كلها before fertilization
+
+326
+00:23:07,450 --> 00:23:10,960
+after fertilizationتعمل على منع الـ polyspermia
+
+327
+00:23:10,960 --> 00:23:17,080
+injection أو fertilize the oocyte by two sperms من
+
+328
+00:23:17,080 --> 00:23:20,460
+خلال تغيير الـ receptor أيضًا بتحافظ على الجنين زي
+
+329
+00:23:20,460 --> 00:23:22,980
+ما جُنّا و هي ال main function of Zoonopelucida
+
+330
+00:23:22,980 --> 00:23:27,500
+خلال المراحل المتقدمة أو المراحل المبكرة من مراحل
+
+331
+00:23:27,500 --> 00:23:34,060
+انقسام الجنة الـ Zoonopelucida بتعمل كبورز أو كشرط
+
+332
+00:23:34,060 --> 00:23:39,880
+مرور بالضبط تتحكم بما يدخل إلى الخليةوتمنع المواد
+
+333
+00:23:39,880 --> 00:23:43,360
+الأخرى من الدخول إلى الخلية وذلك بناء على إحتياج
+
+334
+00:23:43,360 --> 00:23:48,060
+الخلية بالضبط تعمل زي إشارة المورور تسمح بدخول
+
+335
+00:23:48,060 --> 00:23:52,440
+مواد وتمنع دخول مواد أخرى بناء على إحتياج الجنين
+
+336
+00:23:53,610 --> 00:23:57,350
+طبعا بسبب عدم وجود أو فقدان الـ Zoonopelucida
+
+337
+00:23:57,350 --> 00:24:00,250
+الحالية بتسميها hostocompatibility وهي النوع من
+
+338
+00:24:00,250 --> 00:24:02,530
+أنواع الـ human leukocyte antigen الـ
+
+339
+00:24:02,530 --> 00:24:06,190
+Zoonopelucida serve as immunological pairs between
+
+340
+00:24:06,190 --> 00:24:10,590
+mother and the antigenetical different embryo بسبب
+
+341
+00:24:10,590 --> 00:24:13,170
+فقدان الـ Zoonopelucida الـ human leukocyte
+
+342
+00:24:13,170 --> 00:24:17,670
+antigen فبتعمل كحاجز مناعي يحمل جنين ويحمل أم
+
+343
+00:24:17,670 --> 00:24:21,770
+Zoonopelucida بتعمل على تثييل الـ differentiation
+
+344
+00:24:21,770 --> 00:24:27,680
+للـ trophoplastic cell it is normally prevent
+
+345
+00:24:27,680 --> 00:24:31,120
+premature implantation of the cleavage embryo into
+
+346
+00:24:31,120 --> 00:24:33,380
+the wall of the uterine tube طبعا الـ
+
+347
+00:24:33,380 --> 00:24:38,160
+Zoonableucida وجودها ووجودها بشكل hard إلى حد ما
+
+348
+00:24:38,160 --> 00:24:41,220
+في أول أربع أيام إلى تلت أيام من ال fertilization
+
+349
+00:24:41,220 --> 00:24:45,720
+تمنع تحافظ على الجنين وتمنع حدوث implantation مبكر
+
+350
+00:24:45,720 --> 00:24:49,740
+في منطقة غير معدة زي حدوث ال implantation في منطقة
+
+351
+00:24:49,740 --> 00:24:52,520
+ال fallopian tube مما يؤدي إلى حدوث ectopic
+
+352
+00:24:52,520 --> 00:24:55,250
+pregnancyيعني أحد أسباب الـ ectopic pregnancy
+
+353
+00:24:55,250 --> 00:25:01,650
+الخلل في الزونا بليوسيدا طيب وصلت حرفنا أهمية
+
+354
+00:25:01,650 --> 00:25:05,190
+الزونا بليوسيدا ال function الخاصة فيها بعد كده
+
+355
+00:25:05,190 --> 00:25:10,530
+كيف يمكن أن نعمل على ترقيق الزونا بليوسيدا بمعنى
+
+356
+00:25:10,530 --> 00:25:14,210
+آخر في الحقن المجهري جاب العملية ال embryo
+
+357
+00:25:14,210 --> 00:25:17,750
+transfer أو إرجاع ال embryo لازم أعمل حاجة بنسميها
+
+358
+00:25:17,750 --> 00:25:22,150
+thinning يعني بمعنى آخرترفيه أو ترقيق الـ
+
+359
+00:25:22,150 --> 00:25:25,370
+Zoonopelucida ليه بنرقيق الـ Zoonopelucida؟ علشان
+
+360
+00:25:25,370 --> 00:25:29,030
+أسمح للـ Zoonopelucida إنها تتلاشى ببساطة جدا
+
+361
+00:25:29,030 --> 00:25:32,990
+وبسهولة جدا دون تأخير وتساهم في عملية الـ
+
+362
+00:25:32,990 --> 00:25:37,190
+Implantation حاجة بنسميها Assist Hatching in Exit
+
+363
+00:25:37,190 --> 00:25:40,890
+يا إما بعمل Thinning، ترقيق، يا إما بعمل Pouring،
+
+364
+00:25:40,890 --> 00:25:45,010
+هنشوف كيف بعمل Pouring الـ Implantation خلال الحقن
+
+365
+00:25:45,010 --> 00:25:50,990
+المجهري يحتاج إلى عملية بنسميهاهاتشينج تكنيك وهي
+
+366
+00:25:50,990 --> 00:25:55,430
+عمل ثقوب في جدار الزونابلوسيدا وهذا الثقوب ما
+
+367
+00:25:55,430 --> 00:25:58,670
+بتكون غائرة أو بعض الأحيان بتسميها filling of
+
+368
+00:25:58,670 --> 00:26:02,350
+zoonablusida failure of the embryo to escape the
+
+369
+00:26:02,350 --> 00:26:05,390
+zoonablusida is believed to be related to low
+
+370
+00:26:05,390 --> 00:26:08,650
+implantation rate for poor prognosis patients and
+
+371
+00:26:08,650 --> 00:26:14,620
+the main goal of assistant hatchedis overcome this
+
+372
+00:26:14,620 --> 00:26:19,620
+obstacle يعني بيقول لي ببساطة جدا ان في حالات يكون
+
+373
+00:26:19,620 --> 00:26:25,580
+الإجزي فشلت في الحصول على جنين صحيح أو جنين سليم
+
+374
+00:26:25,580 --> 00:26:28,100
+بعد عملية ال implantation بعد عملية ال
+
+375
+00:26:28,100 --> 00:26:32,630
+fertilizationوبعد عملية الـ embryo transfer بكون
+
+376
+00:26:32,630 --> 00:26:37,270
+سببها بشكل أساسي إن زونابليوسيدا فشلت في التكسّر
+
+377
+00:26:37,270 --> 00:26:42,590
+أو زونابليوسيدا ما زالت قوية صلبة منعت الجنين من
+
+378
+00:26:42,590 --> 00:26:46,530
+الخروج فهذا بنسميها embryo to escape prevent the
+
+379
+00:26:46,530 --> 00:26:49,810
+embryo or failure the embryo to escape from
+
+380
+00:26:49,810 --> 00:26:53,670
+زونابليوسيدا بقى ال embryo محضون داخل زونابليوسيدا
+
+381
+00:26:53,670 --> 00:26:58,190
+زونابليوسيدا بقيت كما هي قويةلا تسمح بخروج الـ
+
+382
+00:26:58,190 --> 00:27:01,470
+Embryo فبالتالي فشلت عملية الحقن المجهري في الوصول
+
+383
+00:27:01,470 --> 00:27:06,910
+إلى الـ True Embryo داخل الرحم فبالتالي ممكن أن
+
+384
+00:27:06,910 --> 00:27:10,110
+أتغلب على هذا الموضوع من خلال عملية قوية جدا
+
+385
+00:27:10,110 --> 00:27:16,230
+بنسميها Assist Hatching حاجة برمزولها بالرمز A H
+
+386
+00:27:16,230 --> 00:27:21,530
+طبعا هذه العملية بتحدث في الـ Assist Reproductive
+
+387
+00:27:21,530 --> 00:27:25,490
+Technology عملية مهمة جدابصير من خلالها عمل pores
+
+388
+00:27:25,490 --> 00:27:27,890
+في الـ zona pellucida إما هذه ال pores بتكون
+
+389
+00:27:27,890 --> 00:27:31,410
+mechanical pore أو chemical pore يعني ممكن أستخدم
+
+390
+00:27:31,410 --> 00:27:35,950
+مواد كيميائية و أنزيمات أو ممكن أستخدم طرق
+
+391
+00:27:35,950 --> 00:27:39,610
+ميكانيكية باستخدام ال injection needle و هنشوفها
+
+392
+00:27:39,610 --> 00:27:42,830
+كمان شوية كيف أنا ممكن أستخدم ال injection needle
+
+393
+00:27:43,590 --> 00:27:48,050
+إذا الـ Assisted Hatching في الإجزي بيصير بعد ال
+
+394
+00:27:48,050 --> 00:27:51,410
+fertilization بعد اليوم الخامس من ال fertilization
+
+395
+00:27:51,410 --> 00:27:53,490
+يعني لو صار ال fertilization و ال injection في
+
+396
+00:27:53,490 --> 00:27:57,010
+اليوم الأول يعني المفروض تصير في اليوم الخامس و هو
+
+397
+00:27:57,010 --> 00:27:59,810
+يوم الأربعة مثلا إذا كان يوم السبت هتصير يوم
+
+398
+00:27:59,810 --> 00:28:03,550
+الأربعة وظيفتها أن تعمل pores في zona pellucida
+
+399
+00:28:03,550 --> 00:28:07,270
+علشان تسمح للجنين بالخروج أين دقيقاته و نقله إلى
+
+400
+00:28:07,270 --> 00:28:11,870
+الرحم هل كل الحالات أعملها Assisted Hatching ولا
+
+401
+00:28:11,870 --> 00:28:16,350
+حالات معينة؟في حالات معينة مهم جدا بل لاجب يجب
+
+402
+00:28:16,350 --> 00:28:20,910
+بشكل واجب أنه يعمل assist hatching قبل ما يعمل
+
+403
+00:28:20,910 --> 00:28:25,090
+embryo transfer من أشهر هذه الحالات السيدات اللي
+
+404
+00:28:25,090 --> 00:28:28,730
+عندهم recurrent failure of embryo implantation
+
+405
+00:28:28,730 --> 00:28:32,150
+after embryo transfer يعني عند سيدة خضعت للإجزي
+
+406
+00:28:32,150 --> 00:28:36,170
+تلت أربع أو خمس مرات كل مرة برجع جنين بيصير عنده
+
+407
+00:28:36,170 --> 00:28:39,030
+فشل في ال implantation فبالتالي النتيجة negative
+
+408
+00:28:39,480 --> 00:28:42,220
+رجعت الجنين لدورة تانية، فشل في الـ Implantation
+
+409
+00:28:42,220 --> 00:28:45,500
+النتيجة نيجاتيف وهي نتيجة البييدا الـCG فهذا معناه
+
+410
+00:28:45,500 --> 00:28:48,020
+أن الـZoonopolisida ما صارش فيها dissolving،
+
+411
+00:28:48,020 --> 00:28:50,720
+partial dissolving فبالتالي ما صار Implantation
+
+412
+00:28:50,720 --> 00:28:55,440
+فلازم أعمل assist hatching جاب العملية لل transfer
+
+413
+00:28:55,440 --> 00:28:59,220
+ال embryo exhibiting thickened Zoonopolisida و لا
+
+414
+00:28:59,220 --> 00:29:04,240
+بحكم لجد Zoonopolisida very thick مقاومة لعملية ال
+
+415
+00:29:04,240 --> 00:29:08,540
+penetration فلازم أعملHatching السيدات اللي عندهم
+
+416
+00:29:08,540 --> 00:29:12,260
+advanced age أكتر من 37 سنة السيدات اللي عندهم
+
+417
+00:29:12,260 --> 00:29:16,580
+مستوى ال FSH عالي جدا السيدات .. ال cycle اللي
+
+418
+00:29:16,580 --> 00:29:18,480
+بدأت من ال crime preservation شو يعني crime
+
+419
+00:29:18,480 --> 00:29:21,160
+preservation؟ إن السيدة خضعت ل protocol
+
+420
+00:29:21,160 --> 00:29:26,500
+stimulation أخرجت 35 بوادة حقلت 10 بوادة و الباقي
+
+421
+00:29:26,500 --> 00:29:32,280
+25 عملتلهم preservation جمّتهمالدورة التانية مش
+
+422
+00:29:32,280 --> 00:29:35,940
+هتطبط تخضع لعملية ovulation أو مش هتخضع لعملية
+
+423
+00:29:35,940 --> 00:29:40,040
+stimulation فبضطر باخد من البويضات اللي مخزنة فهذه
+
+424
+00:29:40,040 --> 00:29:43,280
+البويضات طالما مخزنة إذا صار في تغير في تركيب
+
+425
+00:29:43,280 --> 00:29:46,480
+الزونابليوسيدا في ال membrane فبعد عملية الحقل
+
+426
+00:29:46,480 --> 00:29:50,880
+لازم أعمل assist hatching علشان أسمح لل embryo
+
+427
+00:29:50,880 --> 00:29:56,540
+بالخروج بكل بساطة كيف تتم عملية زونابليوسيدا
+
+428
+00:29:56,540 --> 00:30:00,210
+assist hatching أو زونابليوسيدا thinning؟ترفيه
+
+429
+00:30:00,210 --> 00:30:03,910
+الزونابليوسيدا لما اقول thinning بيكون مش كامي مش
+
+430
+00:30:03,910 --> 00:30:07,810
+completely لأ partially completely لأ partially
+
+431
+00:30:07,810 --> 00:30:12,030
+because thinning partially او عمل عدد معين من ال
+
+432
+00:30:12,030 --> 00:30:16,770
+pores او ال holes زونابليوسيدا removal total
+
+433
+00:30:16,770 --> 00:30:20,050
+zoonablusida removal before embryo transfer has
+
+434
+00:30:20,050 --> 00:30:23,690
+been expected to bring out closer contact and
+
+435
+00:30:23,690 --> 00:30:27,350
+communication of the trophoEctoderm of the
+
+436
+00:30:27,350 --> 00:30:31,090
+blastocyst with the endomaterium thereby improving
+
+437
+00:30:31,090 --> 00:30:34,950
+implantation وهذا الهدف الأساسي منها إنه يصير في
+
+438
+00:30:34,950 --> 00:30:38,010
+عندي direct contact ما بين الخلايا الخاصة بالـ
+
+439
+00:30:38,010 --> 00:30:41,930
+embryonic stem cell أو ال embryonic cell و ال
+
+440
+00:30:41,930 --> 00:30:46,250
+endomaterium of female الموجودة في ضلط الرحم مما
+
+441
+00:30:46,250 --> 00:30:49,810
+يحسن عملية ال implantation الـ zoonablusida can be
+
+442
+00:30:49,810 --> 00:30:53,410
+totally removed by chemical or enzymatic method or
+
+443
+00:30:53,410 --> 00:30:58,900
+by using laserيعني انا ممكن اعمل pools او holes او
+
+444
+00:30:58,900 --> 00:31:01,900
+completely removing او partially removing الاربعة
+
+445
+00:31:01,900 --> 00:31:06,080
+بناء على حالة الزيونابلوسيدا من خلال طريقة
+
+446
+00:31:06,080 --> 00:31:10,420
+ميكانيكية طريقة كيميائية او استخدام انزيمات او
+
+447
+00:31:10,420 --> 00:31:16,020
+باستخدام ال laser طلاقات ال laser هناخد اكثر من
+
+448
+00:31:16,020 --> 00:31:19,580
+طريقة جزء هناخده حاليا و الجزء التاني هناخده لما
+
+449
+00:31:19,580 --> 00:31:24,340
+نقول polar body biopsy انوع من انواع التخفيفأول
+
+450
+00:31:24,340 --> 00:31:28,660
+طريقة هي طريقة الـ traditional method وهي عمل
+
+451
+00:31:28,660 --> 00:31:32,600
+pores و holes في الـ zona pellucida من خلال الـ
+
+452
+00:31:32,600 --> 00:31:36,680
+mechanical zona pellucida dissection أو الـ
+
+453
+00:31:36,680 --> 00:31:41,120
+traditional method ببساطة جدا بجيب الطبق اللي فيه
+
+454
+00:31:41,120 --> 00:31:46,320
+الجنين بعد عملية تطوره وانقسامه بوضعه على stage
+
+455
+00:31:46,320 --> 00:31:51,380
+درجة حرارته 37 في منطقة معقمة بنسبة 100% تحت ال
+
+456
+00:31:51,380 --> 00:31:56,760
+inverted microscopeبحمل الجنين وبثبته باستخدام الـ
+
+457
+00:31:56,760 --> 00:31:59,740
+holder أو الـ sucker أو الـ suction holder أو الـ
+
+458
+00:31:59,740 --> 00:32:04,320
+holding tube الموجودة دائما على جهة اليسار اللي
+
+459
+00:32:04,320 --> 00:32:06,920
+أنا كنت بثبت فيها البويضة أثناء عملية ال injection
+
+460
+00:32:06,920 --> 00:32:11,620
+فكده أنا ثبتت الجنين وبجيب ال injection needed
+
+461
+00:32:11,620 --> 00:32:17,540
+اللي كنت أحطن فيها ال sperm بعمل اختراقبعمل اختراق
+
+462
+00:32:17,540 --> 00:32:22,020
+للجنين في الغلاف الخارجي ببدأ من الساعة واحدة و
+
+463
+00:32:22,020 --> 00:32:26,560
+بصل للساعة 11 الساعة واحدة للساعة 11 شو يعني
+
+464
+00:32:26,560 --> 00:32:29,400
+الساعة واحدة للساعة 11؟ لإن الجنين عبارة عن دائرة
+
+465
+00:32:29,400 --> 00:32:35,020
+بقسمها ساعات اتناش ستة تلاتة تسعة انا بدخلت بال
+
+466
+00:32:35,020 --> 00:32:39,300
+needle injection needle من الساعة واحدة هطلع هتخرج
+
+467
+00:32:39,300 --> 00:32:42,680
+ال needle من الساعة 11 بعد كده اعمل releasing لل
+
+468
+00:32:42,680 --> 00:32:49,720
+embryo بإني أخلي ال holder tubeالضغط فيها غير كافي
+
+469
+00:32:49,720 --> 00:32:52,140
+إنه يبدأ يعمل catching للـ embryo فالـ embryo
+
+470
+00:32:52,140 --> 00:32:56,980
+بيصير معلق في ال injection needle باجي بعمل عملية
+
+471
+00:32:56,980 --> 00:33:02,800
+احتكاك بال needle في طرف ال holder tube علشان أعمل
+
+472
+00:33:02,800 --> 00:33:08,240
+تآكل للـ zona pellucida فبهذا الشكل بكون عملت تآكل
+
+473
+00:33:08,240 --> 00:33:11,660
+لجزء من ال zona pellucida وعملت removing أو
+
+474
+00:33:11,660 --> 00:33:15,260
+dissolving هدف نسميها طريقة التآكل أو الطريقة
+
+475
+00:33:15,260 --> 00:33:19,540
+الميكانيكيةطريقة الاحتكاج التي تؤدي لتأكل الزونا
+
+476
+00:33:19,540 --> 00:33:23,720
+بليوسيدا وهي طريقة ميكانيكية خلّينا نشوف بالفيديو
+
+477
+00:33:23,720 --> 00:33:27,460
+كيف تصير هذه الطريقة الميكانيكية اللي من خلالها
+
+478
+00:33:27,460 --> 00:33:31,800
+أنا بتخلص من جزء من الزونا بليوسيدا وهي الـ
+
+479
+00:33:31,800 --> 00:33:38,800
+traditional method طبعا
+
+480
+00:33:38,800 --> 00:33:43,640
+هي عند البويضة عفو للجنين الجنين هذا عند ال holder
+
+481
+00:33:43,640 --> 00:33:47,690
+أو ال suction tubeوهذه ال injection needle أو في
+
+482
+00:33:47,690 --> 00:33:51,370
+بعض الأحيان بيسموها needle الخاصة بعملية
+
+483
+00:33:51,370 --> 00:33:59,730
+zoonablucida dissolving باجي بعمل fixation و بعمل
+
+484
+00:33:59,730 --> 00:34:04,730
+holding لل embryo باستخدام ال holder tube هي
+
+485
+00:34:04,730 --> 00:34:09,610
+الساعة 12 هي الساعة 6 هي الساعة 3 هي الساعة 9 باجي
+
+486
+00:34:09,610 --> 00:34:13,290
+بخترق من الساعة 1 في هذا الاتجاه و بطلع بال needle
+
+487
+00:34:13,290 --> 00:34:17,280
+من الساعة 11إن ما أضرب حوافة في منطقة الزونا
+
+488
+00:34:17,280 --> 00:34:24,100
+باليوسدان الفاتحة دخل
+
+489
+00:34:24,100 --> 00:34:31,160
+بالنيدل المفروض يخرج من الطرف الآخر خرج
+
+490
+00:34:31,160 --> 00:34:34,340
+من الطرف الآخر ما بين الساعة واحدة و اتناشر و خرج
+
+491
+00:34:34,340 --> 00:34:40,600
+ما بين الساعة احداشر و اتناشر بعدين ببدأ يعمل
+
+492
+00:34:40,600 --> 00:34:49,460
+احتكاك بجزء السفلي للولداركدا بيكون بدأ الجنين
+
+493
+00:34:49,460 --> 00:34:52,520
+يخرج زي ما احنا شايفين في هذا المنطقة هذه معناه
+
+494
+00:34:52,520 --> 00:34:56,940
+صار في عدة opening الجنين او الخلايا الـplastomera
+
+495
+00:34:56,940 --> 00:35:00,380
+او الـplastocyst بدأت تنفذ للخارج
+
+496
+00:35:03,860 --> 00:35:09,020
+هذه الفكرة بتسميها ال traditional method او
+
+497
+00:35:09,020 --> 00:35:13,700
+mechanical method for assist hatching فقط لغة هذا
+
+498
+00:35:13,700 --> 00:35:19,360
+كتير الناس بتسويها و مازالت بتحقق نجاحات قوية طيب
+
+499
+00:35:19,360 --> 00:35:24,680
+طب انا عملت hatching و عملت pores او holes في
+
+500
+00:35:24,680 --> 00:35:27,280
+الزولة باليسنا ممكن اعملها جاب العملية ال
+
+501
+00:35:27,280 --> 00:35:32,330
+implantation اه ممكن اعملها طب شو هدفها؟هدفها إن
+
+502
+00:35:32,330 --> 00:35:36,510
+أحصل على مادة وراثية خاصة بالجنين أو أحصل على مادة
+
+503
+00:35:36,510 --> 00:35:40,470
+وراثية خاصة بالأم من أجل الفحوصات الوراثية التي
+
+504
+00:35:40,470 --> 00:35:44,670
+تسمى pre-implantation genetic testing يعني الفحص
+
+505
+00:35:44,670 --> 00:35:49,370
+الجنيني أو الفحص الجيني قبل عملية ال implantation
+
+506
+00:35:49,370 --> 00:35:54,430
+أو الانغراس أو الزراع أو الإعادة ال embryo هذا
+
+507
+00:35:54,430 --> 00:35:58,270
+مصطلح بنسميه polar body biopsy ممكن أخد polar body
+
+508
+00:35:58,270 --> 00:36:01,870
+biopsy يعني أخد جزء من ال polar bodyو أعمله
+
+509
+00:36:01,870 --> 00:36:05,510
+genetic testing فلازم عشان أصل للـ polar body أعمل
+
+510
+00:36:05,510 --> 00:36:08,150
+opening في الـ zoonableucida لأن أحنا عارفين أن
+
+511
+00:36:08,150 --> 00:36:11,670
+البويضة الملقحة فيها two polar body بتكون ما بين
+
+512
+00:36:11,670 --> 00:36:15,690
+البويضة و ما بين ال zoonableucida فلازم أخترق ال
+
+513
+00:36:15,690 --> 00:36:18,910
+zoonableucida عشان أعمل suction لل polar body تحت
+
+514
+00:36:18,910 --> 00:36:23,210
+مصطلح polar body biopsy ال polar body biopsy كان
+
+515
+00:36:23,210 --> 00:36:28,150
+أول ما تم تكوينه في عام و إنجازه في عام 1990 ال
+
+516
+00:36:28,150 --> 00:36:32,200
+polar bodyبيحتوي على المادة الوراثية الخاصة بالأم
+
+517
+00:36:32,200 --> 00:36:35,860
+polar body consists of genetic material related to
+
+518
+00:36:35,860 --> 00:36:39,720
+mother or maternal only خدوا بالكوا من القصة يعنى
+
+519
+00:36:39,720 --> 00:36:43,780
+أي مرض وراثي متعلق بالأم بافحصه من خلال ال polar
+
+520
+00:36:43,780 --> 00:36:48,780
+body أي مرض وراثي متعلق بالجنين بافحصه من خلال ال
+
+521
+00:36:48,780 --> 00:36:50,260
+embryonic cell
+
+522
+00:36:54,000 --> 00:36:56,480
+The analysis polar body can be used to determine
+
+523
+00:36:56,480 --> 00:37:00,860
+chromosomal aniploidy related to maternal meiosis
+
+524
+00:37:00,860 --> 00:37:05,180
+and maternal divide-unbalance translocation
+
+525
+00:37:05,180 --> 00:37:10,320
+chromosome. To detect single gene defect related
+
+526
+00:37:10,320 --> 00:37:13,100
+to who related to the mother related to the
+
+527
+00:37:13,100 --> 00:37:19,100
+maternal allowing for day 3 embryo transfer ممكن
+
+528
+00:37:19,100 --> 00:37:23,980
+أناأستخدم الـ polar body علشان أعمل HLA typing وهي
+
+529
+00:37:23,980 --> 00:37:27,840
+human leukocyte antigen typing وهو التوافق وممكن
+
+530
+00:37:27,840 --> 00:37:33,560
+أفحص من خلالها ال X link disorder خاصة لما نقول X
+
+531
+00:37:33,560 --> 00:37:37,340
+link disorder مفهوم أن معظم الأمراض الوراثية
+
+532
+00:37:37,340 --> 00:37:41,520
+المرتبطة بال X link سواء كانت X link dominant أو X
+
+533
+00:37:41,520 --> 00:37:44,980
+link recessive وعارفينها أن مصدر الخلل بيكون الأم
+
+534
+00:37:44,980 --> 00:37:51,240
+في هذه الحالة أيه ال polar body؟هي الـ GVPD طبعا
+
+535
+00:37:51,240 --> 00:37:55,940
+هذه الـ spindle الـ simply بعدين صار عندى مهاجرة
+
+536
+00:37:55,940 --> 00:37:59,740
+جزء من الخلايا أو عفوا جزء من الكرموزومات إلى
+
+537
+00:37:59,740 --> 00:38:03,280
+الطرف الخلية والجزء الأخر تبقى توني ال fairest
+
+538
+00:38:03,280 --> 00:38:06,760
+polar body بعد ال fertilization أي النواء الذكرية
+
+539
+00:38:06,760 --> 00:38:10,560
+النواء الأنثوية اندمجت صار ال fertilization خرج ال
+
+540
+00:38:10,560 --> 00:38:13,500
+second polar body فانا ممكن أسحب هذا ال polar body
+
+541
+00:38:13,500 --> 00:38:16,520
+و ممكن أسحب اتنين مع بعض هذا له وظيفة و هذا له
+
+542
+00:38:16,520 --> 00:38:22,100
+وظيفةهدف و هدايل و هدف طيب technical aspect of
+
+543
+00:38:22,100 --> 00:38:25,860
+polar body biopsy عرفنا أن ال polar body مهم جدا
+
+544
+00:38:25,860 --> 00:38:29,960
+في تشخيص بعض الأمراض الوراثية الخاصة بالأم بعض
+
+545
+00:38:29,960 --> 00:38:32,120
+الأمراض المتعلقة بال abnormal chromosome
+
+546
+00:38:32,120 --> 00:38:36,980
+structural or number فبالتالي لازم أعمل opening في
+
+547
+00:38:36,980 --> 00:38:40,320
+ال zona pellucida علشان أصل لل polar body و أعمله
+
+548
+00:38:40,320 --> 00:38:44,610
+suction مهم جدا ال timeThe most relevant part of
+
+549
+00:38:44,610 --> 00:38:47,750
+polar body biopsy are timing of biopsy, the
+
+550
+00:38:47,750 --> 00:38:50,050
+opening of zona pellucida, and the removing of
+
+551
+00:38:50,050 --> 00:38:53,470
+polar body يعني تلت مراحل متى أعمل polar body
+
+552
+00:38:53,470 --> 00:38:58,030
+biopsy و لماذا؟ كيف يمكن فتح ال zona pellucida و
+
+553
+00:38:58,030 --> 00:39:01,450
+أعمل opening فيها؟ و كيف يتم إزالة ال polar body؟
+
+554
+00:39:01,450 --> 00:39:05,830
+هذه التلت نقاط الأساسية والمهمة ال timing an
+
+555
+00:39:05,830 --> 00:39:08,510
+oocyte representing a ferrous polar body is
+
+556
+00:39:08,510 --> 00:39:12,150
+usually considered to be metaphysical too يعني أي
+
+557
+00:39:12,150 --> 00:39:16,820
+بويضةيظهر فيها الـ First Polar Body هي بويضة ناضجة
+
+558
+00:39:16,820 --> 00:39:21,860
+وقفت في الـ Metaphase 2 يعني الـ Metaphase الخاص
+
+559
+00:39:21,860 --> 00:39:25,880
+بالإقسام الميوز التاني وتكون صالح لعملية الحقن
+
+560
+00:39:25,880 --> 00:39:29,580
+فبالتالي ممكن أحصل على الـ Polar Body منها الـ
+
+561
+00:39:29,580 --> 00:39:32,160
+Zolopelucida ممكن أعملها Opening من خلال
+
+562
+00:39:32,160 --> 00:39:34,980
+Mechanical زي ما شوفنا قبل شوية الفيديو أو
+
+563
+00:39:34,980 --> 00:39:38,180
+Chemical باستخدام انزين معين هتتكلم عنه وLaser
+
+564
+00:39:38,180 --> 00:39:41,960
+Hatching Opening إنه أنا أستخدم الـ Laser طلقات
+
+565
+00:39:41,960 --> 00:39:46,680
+الـ Laserالـ chemical الـ mechanical أتكلمنا عنه
+
+566
+00:39:46,680 --> 00:39:50,080
+الـ chemical أنه أنا بستخدم solution بيسموه acidic
+
+567
+00:39:50,080 --> 00:39:56,060
+triode solution وهي أول طريقة تم فيها استخدام مادة
+
+568
+00:39:56,060 --> 00:39:59,760
+كيميائية من أجل إزالة جزء من الـ zoonopelucida
+
+569
+00:39:59,760 --> 00:40:04,720
+وعمل zoonopelucida opening هذي استخدموها بعد الـ
+
+570
+00:40:04,720 --> 00:40:09,440
+chemical الـ acidic triode كان بي applied at the
+
+571
+00:40:09,440 --> 00:40:12,870
+embryo stageApplied at the embryo stage, there was
+
+572
+00:40:12,870 --> 00:40:15,690
+an inhibitor effect in the embryonic development
+
+573
+00:40:15,690 --> 00:40:19,570
+when oocyte were exposed to the ascetic triode
+
+574
+00:40:19,570 --> 00:40:22,270
+يعني ال triode أو ال ascetic triode okay أنا ممكن
+
+575
+00:40:22,270 --> 00:40:25,990
+أستخدمه لعمل zoonablucid hatching ولكن ال side
+
+576
+00:40:25,990 --> 00:40:28,410
+effect ايه له او ال disadvantage انه ممكن يعمل
+
+577
+00:40:28,410 --> 00:40:32,710
+inhibition لل embryo development وانا رأسمالي في
+
+578
+00:40:32,710 --> 00:40:36,930
+هذه الحتة ال embryo مش منطق اعمله inhibition لأنه
+
+579
+00:40:36,930 --> 00:40:40,480
+ممكن يعملي abnormalفي الـ embryo development،
+
+580
+00:40:40,480 --> 00:40:42,500
+abnormality في الـ embryo development و أخسر
+
+581
+00:40:42,500 --> 00:40:47,300
+الجنين Therefore, since both oocyte and polar body
+
+582
+00:40:47,300 --> 00:40:50,180
+are sensitive to effect of this acid, zoonia
+
+583
+00:40:50,180 --> 00:40:54,100
+draining by acidic triode solution is unstable for
+
+584
+00:40:54,100 --> 00:40:57,940
+polar body biopsy عشان كده أنا مهمنيش أعمل أو مش
+
+585
+00:40:57,940 --> 00:41:03,200
+لازم أعمل polar body biopsy أو zoonia bilucida
+
+586
+00:41:03,200 --> 00:41:06,800
+opening باستخدام ال chemical material اسمها triode
+
+587
+00:41:06,800 --> 00:41:10,300
+acidأو trial solution اللي هنا بتأثر شكلا سلبية
+
+588
+00:41:10,300 --> 00:41:16,620
+بشكل سلبي على ال embryo وعلى ال oocyte وعلى ال
+
+589
+00:41:16,620 --> 00:41:21,320
+polar body ال laser hatching وهي الطريقة التالية
+
+590
+00:41:21,320 --> 00:41:25,060
+اللتي تستخدم ببساطة جدا ان انا في عندي مطلق لل
+
+591
+00:41:25,060 --> 00:41:29,440
+laser هنشوفها في الفيديو كمان شوية بيجي بيعمل
+
+592
+00:41:29,440 --> 00:41:34,820
+طلقات لل laser في depth معين ب thickness معين بعدد
+
+593
+00:41:34,820 --> 00:41:39,320
+معين كأنه بيعمل thinningو تقشير للـ zona pellucida
+
+594
+00:41:39,320 --> 00:41:44,860
+ببساطة جدا طبعا ال laser assist polar body biopsy
+
+595
+00:41:44,860 --> 00:41:48,240
+is the best method when the oocyte is fixed with
+
+596
+00:41:48,240 --> 00:41:51,180
+the holder capillary يعني بداية زي ما شوفنا في
+
+597
+00:41:51,180 --> 00:41:54,960
+الفيديو بعمل laser hatching إما بعملها للإمبريو أو
+
+598
+00:41:54,960 --> 00:41:58,740
+بعملها للبويضة و طالما أنا بتعمل polar body biopsy
+
+599
+00:41:58,740 --> 00:42:03,520
+إذا بعملها للبويضة الغير ملطحة أو الملطحة بناء أن
+
+600
+00:42:03,520 --> 00:42:07,980
+أنا شو إيه بتشتغل و الأفضل أعملها لالملقحة بعد
+
+601
+00:42:07,980 --> 00:42:11,680
+تكوين وظهور ال tube polar body ال first وال second
+
+602
+00:42:11,680 --> 00:42:17,120
+بعمل fixation ل .. او بعمل حاجة بنسميها fixation ل
+
+603
+00:42:17,120 --> 00:42:22,580
+.. او catching ل ال oocyte باستخدام ال holder tube
+
+604
+00:42:22,580 --> 00:42:26,920
+بعدين باجي بشعاع ال laser بحدد اند الساعة 12 لساعة
+
+605
+00:42:26,920 --> 00:42:31,080
+3 مناطق الطلاقات اللي هيطلق عليها ال laser ب depth
+
+606
+00:42:31,080 --> 00:42:37,000
+معينكأنه بعملي تقشير للـ zona pellucida هنشوفها
+
+607
+00:42:37,000 --> 00:42:40,820
+بالفيديو ال opening تقريبا بتكون ال size تبعها من
+
+608
+00:42:40,820 --> 00:42:44,520
+15 إلى 25 ميكرو متر و بتكون ما بين الساعة التانية
+
+609
+00:42:44,520 --> 00:42:47,100
+والساعة التلاتة الساعة التانية والساعة التلاتة
+
+610
+00:42:47,100 --> 00:42:53,120
+طبعا بيصير عندي thinning لل zona pellucida and by
+
+611
+00:42:53,120 --> 00:42:57,280
+pushing the biopsy capillary into prevental space
+
+612
+00:42:57,280 --> 00:43:02,280
+both polar body can be removed togetherيعني بمعنى
+
+613
+00:43:02,280 --> 00:43:08,640
+أخر بعد أن أنا معملت holding و fixation ل ال .. ال
+
+614
+00:43:08,640 --> 00:43:13,080
+oocyte استخدام ال .. ال holder tube و أعرضت طلقات
+
+615
+00:43:13,080 --> 00:43:15,600
+ال laser للمنطقة اتنين و تلاتة فصار في عندي فتحة
+
+616
+00:43:15,600 --> 00:43:18,260
+في المنطقة ما بين الساعة اتنين و تلاتة باجب ال
+
+617
+00:43:18,260 --> 00:43:22,380
+aspiration tube بدخل من خلال الفتحة و بعمل suction
+
+618
+00:43:22,380 --> 00:43:25,960
+لل polar body ممكن أعمل لل polar body الأول ممكن
+
+619
+00:43:25,960 --> 00:43:29,160
+أعمل لل polar body التاني كل واحد على حد أو ممكن
+
+620
+00:43:29,160 --> 00:43:35,420
+أعملهم مع بعضطبعا اعمل .. بقول في trick فني انه
+
+621
+00:43:35,420 --> 00:43:41,900
+بقول لي ببساطة و انت داخل ال aspiration tube اعملت
+
+622
+00:43:41,900 --> 00:43:46,240
+catching لل first polar body حاول ارجع جدّم شوية و
+
+623
+00:43:46,240 --> 00:43:49,920
+بعدين اعمل aspiration لان عملية التقديم بتحرك ال
+
+624
+00:43:49,920 --> 00:43:52,740
+first polar body لان عارفين احنا ال first polar
+
+625
+00:43:52,740 --> 00:43:55,880
+body بيكون في الأول يلي من جهة اليسار ال second
+
+626
+00:43:55,880 --> 00:43:58,720
+polar body يعني انت كأنك بتطلع في الأول ال second
+
+627
+00:43:58,720 --> 00:44:02,820
+polar bodyبعدين بتطلع ال first polar body لما تعمل
+
+628
+00:44:02,820 --> 00:44:06,100
+catching للفئر ال second polar body اعمل عملية
+
+629
+00:44:06,100 --> 00:44:11,420
+ادخال ل ال aspiration tube بزيادة شوية عشان يتحرك
+
+630
+00:44:11,420 --> 00:44:16,560
+ال first polar body من مكانه و يصير سهل الحركة من
+
+631
+00:44:16,560 --> 00:44:21,080
+أجل تثير عملية ال suction الخاصة فيهThe procedure
+
+632
+00:44:21,080 --> 00:44:26,240
+is accurate, reproducible and safe and it also
+
+633
+00:44:26,240 --> 00:44:28,360
+reduces the number of cells which cannot be
+
+634
+00:44:28,360 --> 00:44:32,080
+diagnosed as a result of a technical problem
+
+635
+00:44:32,080 --> 00:44:35,840
+during biopsy procedure يعني مهم جدا بيقولك هذا
+
+636
+00:44:35,840 --> 00:44:40,560
+الطريقة طريقة ال laser hatching طريقة سهلة آمنة
+
+637
+00:44:40,560 --> 00:44:45,920
+مضمونة إلى حد ما تقلل عدد الخلال التي تخرج من ال
+
+638
+00:44:45,920 --> 00:44:51,110
+embryo أو البوايدة خلالالـ Polar Body Biopsy والتي
+
+639
+00:44:51,110 --> 00:44:56,350
+قد لا تساهم في عملية التشخيص الجيني طبعا هذه
+
+640
+00:44:56,350 --> 00:45:01,250
+الفكرة ببساطة هذه البوايضة عند ال first polar body
+
+641
+00:45:01,250 --> 00:45:04,630
+موجود في ال aspiration needle و عند ال second
+
+642
+00:45:04,630 --> 00:45:08,650
+polar body و هذا ال first polar body لأن دائما هذه
+
+643
+00:45:08,650 --> 00:45:11,430
+البوايضة يكون ال first polar body عند الساعة 12
+
+644
+00:45:11,430 --> 00:45:15,910
+for exampleو ال second polar body على يمينه دائما
+
+645
+00:45:15,910 --> 00:45:19,130
+بكون على يمينه فبالتالي لما انت تعمل دخول بال
+
+646
+00:45:19,130 --> 00:45:22,970
+aspiration needle او aspiration pipet هتسحب في
+
+647
+00:45:22,970 --> 00:45:25,450
+البداية ال first polar body .. ال second polar
+
+648
+00:45:25,450 --> 00:45:29,980
+bodyولكن في البداية هيكون ال second polar body هنا
+
+649
+00:45:29,980 --> 00:45:33,660
+هتدخل بال aspiration tube شوية فبالتالي بتكون حركة
+
+650
+00:45:33,660 --> 00:45:38,340
+ال polar body هذا عن مكانه فبتسحب ال second polar
+
+651
+00:45:38,340 --> 00:45:41,800
+body بتدخله داخل ال aspiration tube وبعدين بتسحب
+
+652
+00:45:41,800 --> 00:45:45,080
+ال second polar body كما هو ال first وال second
+
+653
+00:45:45,080 --> 00:45:49,200
+بيكون سحتهم مع بعض خليني أشوف الفيديو اللي بتكلم
+
+654
+00:45:49,200 --> 00:45:53,280
+عن هذه العملية وبعدين نرجع للموضوع مرة أخرى
+
+655
+00:46:00,380 --> 00:46:03,620
+طبعا هنا هيتكلم عن ال assist hatching باستخدام ال
+
+656
+00:46:03,620 --> 00:46:07,520
+laser طبعا يحدد المناطق هيما بين الساعة 2 والساعة
+
+657
+00:46:07,520 --> 00:46:11,600
+3 هيعمل اطلاق لشعار ال laser في المناطق هذه
+
+658
+00:46:19,130 --> 00:46:22,930
+هو عنده زي حاجة تشبه القناص إلى حد ما زي شرط
+
+659
+00:46:22,930 --> 00:46:26,270
+القناص بتغطي في هذه المنطقة تشوف حدد ال depth لوين
+
+660
+00:46:26,270 --> 00:46:31,250
+نهايته هذه حدد و بعمل clicking على الذر كأنه بطلق
+
+661
+00:46:31,250 --> 00:46:35,410
+لل laser هنا بيكون حدد المكان مجرد ما ضغط على الذر
+
+662
+00:46:35,410 --> 00:46:39,030
+بيصير اطلاق لشعار ال laser بيكون معايره ل depth
+
+663
+00:46:39,030 --> 00:46:43,370
+معين بقوة معينة هذي ال Empyrenic stem cell في
+
+664
+00:46:43,370 --> 00:46:43,730
+الغالب
+
+665
+00:47:07,290 --> 00:47:10,870
+شوفش هنا كتب start firing لما ضغط على الذر هذا
+
+666
+00:47:10,870 --> 00:47:15,470
+الذر ده اسمها start firing يعني بداية إطلاق ال
+
+667
+00:47:15,470 --> 00:47:18,410
+laser فبطلقها ب depth معين في مكان معين بناء على
+
+668
+00:47:18,410 --> 00:47:23,540
+المنطقة اللي حدثأيضًا هنا بيقول يا كام holes بده
+
+669
+00:47:23,540 --> 00:47:26,720
+بده ال width بده ال size ده ال hole و كام hole بده
+
+670
+00:47:26,720 --> 00:47:29,720
+ستة سبعة تمانية بناء على حجم الخلية اللي بده
+
+671
+00:47:29,720 --> 00:47:34,080
+يسحبها طبعًا هنا بده يسحب ال embryo cells احنا
+
+672
+00:47:34,080 --> 00:47:36,560
+بنحكي على ال biopsy بنفس الطريقة ولكن هنا بده يسحب
+
+673
+00:47:36,560 --> 00:47:39,700
+ال embryo cells فبالتالي بيكون أعمق علشان يصل ال
+
+674
+00:47:39,700 --> 00:47:40,940
+embryo بشكل أسلوب
+
+675
+00:48:08,590 --> 00:48:12,370
+هكذا بيكون عمل assist hatching باستخدام ال laser
+
+676
+00:48:12,370 --> 00:48:17,350
+أخرج embryonic stem سل واحدة طبعا ال polar body
+
+677
+00:48:17,350 --> 00:48:20,910
+مهم جدا مهم جدا ال polar body علشان يكشف على
+
+678
+00:48:20,910 --> 00:48:24,110
+الأمراض الوراثية المتعلقة بال female بشكل أساسي
+
+679
+00:48:38,850 --> 00:48:42,930
+هذا بيقلل كمية ال contamination التي يمكن أن تحدث
+
+680
+00:48:42,930 --> 00:48:46,990
+فبالتالي من خلال تقليل عدد الخلال التي يمكن أن
+
+681
+00:48:46,990 --> 00:48:51,890
+تخرج مع ال polar body مع ال polar body هذا شكل أخر
+
+682
+00:48:51,890 --> 00:48:56,830
+من الأشكال الخاصة فيه طبعا هذه بدخل ب aspiration
+
+683
+00:48:56,830 --> 00:49:01,490
+needle سحب أو ثبت ال first polar body بعدين
+
+684
+00:49:01,490 --> 00:49:04,890
+بيسحبوا بهذا الشكل سحب ال second polar body بعدين
+
+685
+00:49:04,890 --> 00:49:08,570
+سحب ال first polar body طلع منهم و أضافهم في منطقة
+
+686
+00:49:08,960 --> 00:49:13,240
+خالية كدا سنكتفي بهذا القدر في هذه المحاضرة على
+
+687
+00:49:13,240 --> 00:49:16,640
+أمل أن نلتقي في محاضرة قادمة ان شاء الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/WkQtL6R0CPk.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/WkQtL6R0CPk.srt
new file mode 100644
index 0000000000000000000000000000000000000000..38d0c3945d7325fcf7c4e511ecacf760e1330a10
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/WkQtL6R0CPk.srt
@@ -0,0 +1,2639 @@
+1
+00:00:02,600 --> 00:00:06,900
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:06,900 --> 00:00:12,620
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين، طلابنا 
+
+3
+00:00:12,620 --> 00:00:17,240
+الأفاضل، نرجو من الله أن تكونوا جميعا بخير وبصحة 
+
+4
+00:00:17,240 --> 00:00:22,790
+جيدة، استكمالًا لما بدأنا فيه في مساق مواضيع خاصة في 
+
+5
+00:00:22,790 --> 00:00:27,190
+العلوم الطبية المخبرية، والذي سوف يتناول هذا المساق 
+
+6
+00:00:27,190 --> 00:00:31,070
+عملية التلقيح الصناعي أو الحقن المجهري، طرقه 
+
+7
+00:00:31,070 --> 00:00:36,630
+وأسبابه وأساليبه، اليوم سوف نبدأ في Chapter جديد 
+
+8
+00:00:36,630 --> 00:00:41,610
+وهو الـ Chapter الثاني، والذي سوف يتحدث عن عملية نقل 
+
+9
+00:00:41,610 --> 00:00:46,110
+الجاميتات، والجاميتات المقصود بها هي عبارة عن النطف
+
+10
+00:00:46,110 --> 00:00:49,250
+الذكورية المتمثلة في الـ Spermatozoa والنطف
+
+11
+00:00:49,250 --> 00:00:53,430
+الأنثوية المتمثلة في الـ Oocyte، كيف يتم نقلها من 
+
+12
+00:00:53,430 --> 00:00:56,730
+مكان التصنيع إلى مكان الاستخدام، والمقصود 
+
+13
+00:00:56,730 --> 00:01:00,490
+بالاستخدام؟ هي عبارة عن منطقة الـ Fertilization 
+
+14
+00:01:00,490 --> 00:01:05,190
+والتي تحدث في الـ Fallopian Tube عند الفيميل، مرورا
+
+15
+00:01:05,190 --> 00:01:10,150
+بالـ Fertilization، وانهاء بمرض يحدث عند السيدات 
+
+16
+00:01:10,150 --> 00:01:15,530
+يؤدي إلى عدم إنجاب يسمى Ectopic Pregnancy، هذه أهم 
+
+17
+00:01:15,530 --> 00:01:20,070
+النقاط اللي احنا هنتكلم فيها خلال هذه المحاضرة 
+
+18
+00:01:20,070 --> 00:01:28,130
+وعلى مدار الشابتر هذا بشكل كامل، بداية سوف نتكلم
+
+19
+00:01:28,130 --> 00:01:35,430
+عن الـ Fertilization، الـ Fertilization كمصطلح يعني 
+
+20
+00:01:35,430 --> 00:01:39,780
+الإخصاب، يعني اتحاد الجاميتات الذكرية مع الجاميتات 
+
+21
+00:01:39,780 --> 00:01:44,640
+الأنثوية في منطقة معينة، واندماجهم مع بعضهم البعض، 
+
+22
+00:01:44,640 --> 00:01:49,320
+وخاصة في الـ Female Reproductive Tract، مما يؤدي
+
+23
+00:01:49,320 --> 00:01:54,220
+إلى تكوين خلية تسمى الزيجوت، الزيجوت هي عبارة عن
+
+24
+00:01:54,220 --> 00:01:59,600
+أول خلية تنتج من خلال اندماج الجاميتات الذكرية مع 
+
+25
+00:01:59,600 --> 00:02:04,200
+الجاميتات الأنثوية، تحت مصطلح Fertilization، وعشان 
+
+26
+00:02:04,200 --> 00:02:07,820
+أبدأ أحكي عن الـ Fertilization، لازم أبدأ أحكي عن 
+
+27
+00:02:07,820 --> 00:02:11,440
+أول حدث بيصير عند الـ Female، وهو عبارة عن الـ 
+
+28
+00:02:11,440 --> 00:02:16,120
+Ovulation، فالـ Ovulation كمصطلح يقصد به عملية 
+
+29
+00:02:16,120 --> 00:02:21,860
+الإباضة، عرفنا إن الفيميل تصل لسنة رشد وهي تملك عدد 
+
+30
+00:02:21,860 --> 00:02:27,020
+معين من البويضات يقدر بـ 250 ألف بويضة، ربع مليون 
+
+31
+00:02:27,020 --> 00:02:31,660
+بويضة، لا يتم استخدام كل هذه البويضات، إنما معظمها
+
+32
+00:02:31,660 --> 00:02:37,400
+يدخل في الـ Apoptosis، تحت مصطلح Atresia، فبالتالي هناك
+
+33
+00:02:37,400 --> 00:02:41,960
+عدد من البويضات يتم استخدام بشكل شهري في مصطلح الـ 
+
+34
+00:02:41,960 --> 00:02:46,970
+Menstrual Cycle، بعضهم يخصب ويؤدي لتكوين جنين، والبعض 
+
+35
+00:02:46,970 --> 00:02:51,550
+الآخر يخرج مع الدورة الشهرية في عملية الـ Bleeding 
+
+36
+00:02:51,550 --> 00:02:56,870
+وعرفنا أن الدورة الشهرية تتراوح ما بين 28 يوم من 
+
+37
+00:02:56,870 --> 00:03:00,850
+البداية حتى النهاية، بس كمان بينما كان الـ Duration 
+
+38
+00:03:00,850 --> 00:03:06,190
+مع الـ Bleeding خمس أيام، As Average في المتوسط
+
+39
+00:03:06,190 --> 00:03:09,250
+الدورة الشهرية، At The Middle Point Of Menstrual
+
+40
+00:03:09,250 --> 00:03:12,550
+Cycle، في اليوم الـ 13 والـ 14 بيحدث عملية الـ 
+
+41
+00:03:12,550 --> 00:03:18,540
+Ovulation، حيث تتطور وتنضج عدد من الفوليكول تسمى
+
+42
+00:03:18,540 --> 00:03:21,780
+Graafian Follicle، وإذا نضجت تسميها Mature Graafian 
+
+43
+00:03:21,780 --> 00:03:27,040
+Follicle، تحتوي بداخلها على بويضة واحدة ناضجة، هذه 
+
+44
+00:03:27,040 --> 00:03:31,460
+البويضة الواحدة الناضجة يجب أن تستقر وتدخل في
+
+45
+00:03:31,460 --> 00:03:35,420
+مرحلة Arrested Stage، في مرحلة يسميها Prophase Of 
+
+46
+00:03:35,420 --> 00:03:39,080
+The First Meiotic Division، Prophase Of The
+
+47
+00:03:39,080 --> 00:03:42,600
+First Meiotic Division، Prophase Of The First
+
+48
+00:03:42,600 --> 00:03:45,340
+Meiotic Division، يعني هذه البويضة الناضجة عشان
+
+49
+00:03:45,340 --> 00:03:49,960
+أقول إنها ناضجة و Graafian Follicle ناضجة، لازم هذه 
+
+50
+00:03:49,960 --> 00:03:54,520
+الفوليكول تحتوي على بويضة داخلها في مرحلة Arrested
+
+51
+00:03:54,520 --> 00:03:58,900
+في الانقسام الميوزي الأول في أي طور من انقسام 
+
+52
+00:03:58,900 --> 00:04:02,900
+الميوزي الأول، لـ Prophase، في هذه اللحظة تبدأ
+
+53
+00:04:02,900 --> 00:04:08,930
+البويضة تظهر على سطح الـ Ovary، بعد كده البويضة 
+
+54
+00:04:08,930 --> 00:04:11,730
+لازم تستجيب لبعض الهرمونات، أشهرها الـ Follicle
+
+55
+00:04:11,730 --> 00:04:15,210
+Stimulating Hormone والـ Luteinizing Hormone اللي
+
+56
+00:04:15,210 --> 00:04:20,150
+بيعملوا عملية نضوج وتطور دراماتيكي للبويضة عشان
+
+57
+00:04:20,150 --> 00:04:24,190
+تصل للقطر المطلوب و لعدد الكروموسومات المطلوبة، 
+
+58
+00:04:24,190 --> 00:04:29,170
+The First Meiotic Division Will Be Completely Then
+
+59
+00:04:29,170 --> 00:04:32,590
+The Second Meiotic Division Will Be Start Until
+
+60
+00:04:32,590 --> 00:04:36,560
+Metaphase Stage، يعني وصلت الفوليكول الـ Graafian 
+
+61
+00:04:36,560 --> 00:04:43,440
+Follicle لحد النضوج، هيكتمل انقسام الميوزي الأول ثم 
+
+62
+00:04:43,440 --> 00:04:48,060
+تبدأ البويضة في الدخول في انقسام الميوزي الثاني 
+
+63
+00:04:48,060 --> 00:04:53,180
+وتستقر في الـ Metaphase، من أشهر الـ Marker الخاصة 
+
+64
+00:04:53,180 --> 00:04:56,160
+باستقرارها في الـ Metaphase ظهور ما يُعرف اسم 
+
+65
+00:04:56,160 --> 00:05:00,000
+الـ First Polar Body، وعارفين أن الـ First Polar
+
+66
+00:05:00,000 --> 00:05:04,740
+Body عبارة عن جزء من الكروموسومات بعد عملية انقسام 
+
+67
+00:05:04,740 --> 00:05:08,930
+السيتوبلازمي،  أولًا، بيتودّي لتكوين خلية، هذه الخلية
+
+68
+00:05:08,930 --> 00:05:12,810
+تحتوي على كمية قليلة جدًا من الـ Cytoplasm لا تكفي 
+
+69
+00:05:12,810 --> 00:05:16,190
+للاستقرار أو للبقاء أو لاستمرار عملية الانقسام 
+
+70
+00:05:16,190 --> 00:05:20,310
+فبسميها The Rest Polar Body، وقوف الخلية أو
+
+71
+00:05:20,310 --> 00:05:23,450
+البويضة عند الـ Metaphase الخاص بالانقسام الميوزي
+
+72
+00:05:23,450 --> 00:05:28,310
+الثاني دليل على نضوجها وقدرتنا على استخدامها في 
+
+73
+00:05:28,310 --> 00:05:33,320
+عملية الـ Fertilization، يعني بمعنى آخر لا يمكن تلقيح 
+
+74
+00:05:33,320 --> 00:05:39,280
+أي بويضة إلا عند وقوفها في الـ Metaphase Stage الخاص
+
+75
+00:05:39,280 --> 00:05:44,160
+بالانقسام الميوزي الثاني، يعني بويضة زائد First Polar
+
+76
+00:05:44,160 --> 00:05:48,240
+Body، ساعتها بقول والله دي البويضة أستطيع أن أدخلها 
+
+77
+00:05:48,240 --> 00:05:56,280
+في عملية التلقيح الصناعي أو الحقن المجهري، After
+
+78
+00:05:56,280 --> 00:05:58,920
+The First Meiotic Division, The First Polar Body 
+
+79
+00:05:58,920 --> 00:06:08,430
+Will Be Appeared، هذا هو المقياس لإنه ينقص 
+
+80
+00:06:08,430 --> 00:06:12,230
+الميوزي الأول ودخلت في انقسام الميوزي الثاني
+
+81
+00:06:12,230 --> 00:06:16,450
+استعدادا لعملية الـ Fertilization، الـ Stimulus For 
+
+82
+00:06:16,450 --> 00:06:22,470
+Ovulation Is The Wave Or Surge Of LH Secreted By
+
+83
+00:06:22,470 --> 00:06:25,390
+Anterior Lobe Of Pituitary Gland In The Middle Point
+
+84
+00:06:25,390 --> 00:06:31,580
+Of Menstrual Cycle، يعني نقطة التحفيز الخاصة بعملية 
+
+85
+00:06:31,580 --> 00:06:36,560
+الإباضة تنتج وتحدث بفعل إفراز كميات هائلة من
+
+86
+00:06:36,560 --> 00:06:39,880
+الـ Luteinizing Hormone تُعرف باسم الـ LH Wave يعني
+
+87
+00:06:39,880 --> 00:06:44,380
+الموجة الخاصة بالـ LH، والذي يُفرز كما أسلفنا من 
+
+88
+00:06:44,380 --> 00:06:47,740
+الـ Anterior Lobe Of Pituitary Gland في منتصف الدورة 
+
+89
+00:06:47,740 --> 00:06:49,460
+الشهرية، يوم 13 أو 14
+
+90
+00:07:00,060 --> 00:07:06,640
+بمجرد إفراز كميات مهولة من الـ LH، يتم بدرجة وبوقت 
+
+91
+00:07:06,640 --> 00:07:11,140
+قصير جدًا بعد هذه العملية، بعد إفراز الـ LH بكمية من
+
+92
+00:07:11,140 --> 00:07:15,460
+الوقت قليلة جدًا، تزداد و تزيد  تضخّم الدم بكمية كبيرة 
+
+93
+00:07:15,460 --> 00:07:18,880
+جدا إلى الـ Outer Layer الخاصة بالـ Follicular Wall
+
+94
+00:07:18,880 --> 00:07:24,360
+اللي بحتوي على بويضة ناضجة، مع زيادة تضخّم الدم 
+
+95
+00:07:24,360 --> 00:07:30,240
+بيصير Leakage تسريب لـ Plasma Protein Into The
+
+96
+00:07:30,240 --> 00:07:34,540
+Tissue Through Post Capillary Venules، مما يؤدي إلى 
+
+97
+00:07:34,540 --> 00:07:38,520
+تكوين ما يُعرف باسم Local Edema، يعني كام إفراز 
+
+98
+00:07:38,520 --> 00:07:42,420
+كمية هائلة من الـ Luteinizing Hormone في منتصف الدورة
+
+99
+00:07:42,420 --> 00:07:47,040
+الخاصة في الأنثى يليه مباشرة بكمية قليلة جدًا من
+
+100
+00:07:47,040 --> 00:07:53,470
+الوقت، بإفراز كمية كبيرة و اتضافة كمية كبيرة جدا من
+
+101
+00:07:53,470 --> 00:07:58,230
+الدم لهذا المكان يليه إفراز كمية هائلة و تثيرية 
+
+102
+00:07:58,230 --> 00:08:01,150
+كمية هائلة من الـ Plasma Protein في الـ Tissue عن 
+
+103
+00:08:01,150 --> 00:08:06,310
+طريق الـ Post Capillary Venules، مما يؤدي إلى تدوين 
+
+104
+00:08:06,310 --> 00:08:12,730
+Local Edema، المقصود بالـ Local Edema هي عبارة عن
+
+105
+00:08:12,730 --> 00:08:16,750
+إفراز كمية كبيرة جدًا من الـ Fluid، So The Edema
+
+106
+00:08:16,750 --> 00:08:21,360
+And The Releasing Of Certain Locally Activity 
+
+107
+00:08:21,360 --> 00:08:24,160
+Compounds Such As Prostaglandin, Histamine,
+
+108
+00:08:24,300 --> 00:08:28,640
+Vasopressin, Plasmin And G-Activator Will Provide
+
+109
+00:08:28,640 --> 00:08:31,660
+A Starting Point For A Series Of Reactions That
+
+110
+00:08:31,660 --> 00:08:34,900
+Result In The Local Production Of A Matrix
+
+111
+00:08:34,900 --> 00:08:39,080
+Metalloproteinase Family Of Lytic Enzymes That
+
+112
+00:08:39,080 --> 00:08:42,520
+Degrade A Compound Of The Extracellular Matrix
+
+113
+00:08:42,520 --> 00:08:48,770
+يعني، هتنتج كمية كبيرة جدا من Blood بالإضافة إلى
+
+114
+00:08:48,770 --> 00:08:52,010
+الـ Leakage الخاص بالـ Plasma Protein وحدوث الـ 
+
+115
+00:08:52,010 --> 00:08:56,310
+Local Edema، يتبعها مباشرة إفراز كميات كبيرة جدا
+
+116
+00:08:56,310 --> 00:08:59,690
+من الـ Active Compound، على رأسها الـ Prostaglandin 
+
+117
+00:08:59,690 --> 00:09:05,710
+يليها الهيستامين ثم Vasopressin ثم الـ 
+
+118
+00:09:05,710 --> 00:09:09,670
+Plasminogen Activator، هذه كلها عبارة عن مواد كيميائية
+
+119
+00:09:09,670 --> 00:09:14,670
+تشبه إلى حد ما الـ Hormone Action، تساعد في عملية 
+
+120
+00:09:14,670 --> 00:09:18,140
+الـ Ovulation، كيف تساعد في عملية الـ Ovulation؟ من 
+
+121
+00:09:18,140 --> 00:09:25,020
+خلال إفرازها والمساعدة في عمل Series Or Serial Of 
+
+122
+00:09:25,020 --> 00:09:29,760
+Reaction، هذه الـ Reaction Like Reaction Cascade، هذه 
+
+123
+00:09:29,760 --> 00:09:34,800
+الـ Reaction بتعمل على إفراز كمية من Matrix 
+
+124
+00:09:34,800 --> 00:09:40,080
+Metalloproteinase Family، Which Working As Lytic
+
+125
+00:09:40,080 --> 00:09:44,890
+Enzyme، هذه الـ Metalloproteinase Family بتشتغل على 
+
+126
+00:09:44,890 --> 00:09:49,710
+شكل Lytic Enzyme، يعني إنزيمات محللة مما يعمل 
+
+127
+00:09:49,710 --> 00:09:53,630
+ويؤدي إلى تحليل الخلايا الخارجية لـ Graafian 
+
+128
+00:09:53,630 --> 00:09:58,930
+Follicle، والسماح للبويضة الناضجة بالخروج، هذه فكرة 
+
+129
+00:09:58,930 --> 00:10:02,930
+الـ Ovulation، At That Same Time في نفس الوقت اللي 
+
+130
+00:10:02,930 --> 00:10:06,390
+بتتم فيها إفراز الكملها، إن الـ Active Compound 
+
+131
+00:10:06,390 --> 00:10:11,300
+بالإضافة إلى الـ Lytic Enzyme، يتم إفراز مُركّب آخر،
+
+132
+00:10:11,300 --> 00:10:15,960
+هو عبارة عن الـ Hyaluronic Acid، هذا الـ Hyaluronic 
+
+133
+00:10:15,960 --> 00:10:20,500
+Acid، By Cells Of The Cumulus، Results In Losing Of 
+
+134
+00:10:20,500 --> 00:10:25,600
+The Cells Surrounding The Egg، بمعنى آخر، مرافق 
+
+135
+00:10:25,600 --> 00:10:32,040
+للأحداث السابقة، يفرز مادة تسمى Hyaluronic Acid عن
+
+136
+00:10:32,040 --> 00:10:35,740
+طريق خلايا، By The Cells Of The Cumulus، عن طريق 
+
+137
+00:10:35,740 --> 00:10:39,460
+خلايا تسمى Cumulus Cells، هذه الخلايا أو هذه المادة
+
+138
+00:10:39,460 --> 00:10:44,100
+اللي وفرزت تسمح بتحلل وتفكك الخلايا المحيطة 
+
+139
+00:10:44,100 --> 00:10:48,880
+بالبويضة، علشان تكون البويضة سهلة الانتقال، سهلة 
+
+140
+00:10:48,880 --> 00:10:53,240
+الخروج، سهلة التخصيب، لأنه ليس منطقي البويضة تخرج 
+
+141
+00:10:53,450 --> 00:10:58,310
+ويكون محيطها كمية كبيرة وهائلة جدا من الخلايا الـ
+
+142
+00:10:58,310 --> 00:11:02,630
+lytic action of the matrix metalloproteinase produce
+
+143
+00:11:02,630 --> 00:11:06,570
+an inflammatory-like reaction يعني هذه الكمية
+
+144
+00:11:06,570 --> 00:11:10,910
+المهولة من الـ lytic action بفعل إفراز الـ matrix
+
+145
+00:11:10,910 --> 00:11:15,150
+metalloproteinase or the material
+
+146
+00:11:15,150 --> 00:11:20,230
+or the enzyme بتعمل عمل الـ inflammatory substance
+
+147
+00:11:20,920 --> 00:11:23,800
+شو يعني إذا بيصير عندي inflammatory؟ أول علامات ال
+
+148
+00:11:23,800 --> 00:11:29,260
+inflammation عارفين swelling, fever, redness و ال
+
+149
+00:11:29,260 --> 00:11:32,740
+redness معناها زيادة تضافة الدم في المنطقة اللي
+
+150
+00:11:32,740 --> 00:11:35,680
+صار فيها ال inflammation أو اللي وصل إليها العوامل
+
+151
+00:11:35,680 --> 00:11:39,240
+اللي بتعمل inflammation فإنه يشتغل الـ matrix
+
+152
+00:11:39,240 --> 00:11:43,540
+metalloproteinase as inflammatory reaction هذا مهم
+
+153
+00:11:43,540 --> 00:11:48,610
+جدا و بيساعد بشكل كبير جدا على حدوث rapture للـ
+
+154
+00:11:48,610 --> 00:11:52,950
+outer layer أو الـ outer wall الخاص بالـ Graafian
+
+155
+00:11:52,950 --> 00:11:59,410
+Follicle مما يسمح بخروج البويضة طبعا ما بيصير و
+
+156
+00:11:59,410 --> 00:12:02,590
+ما بيفرز و ما بيصير ال rupture و ما بيصير ال
+
+157
+00:12:02,590 --> 00:12:06,970
+ovulation بعد خروج ال luteinizing hormone و وصوله
+
+158
+00:12:06,970 --> 00:12:13,990
+إلى أعلى بيك بمعدل 28 إلى 36 ساعة يعني لو السيدة
+
+159
+00:12:13,990 --> 00:12:19,350
+عملت تحليل للـ LH و قالت و الله أو وجدت أن الـ LH
+
+160
+00:12:19,350 --> 00:12:25,410
+وصل لأعلى بيك الساعة واحدة صباحًا غبرًا مثلًا عدت 28
+
+161
+00:12:25,410 --> 00:12:29,730
+ساعة على الأقل بعدين هيبدأ عملية ال ovulation و
+
+162
+00:12:29,730 --> 00:12:33,450
+البويضة تخرج من ال Graafian follicle و تصل لل
+
+163
+00:12:33,450 --> 00:12:39,030
+fallopian tube هذه الأحداث أو الأحداث اللي بتصير
+
+164
+00:12:39,030 --> 00:12:42,990
+بشكل متتالي و بشكل متتابع علشان هالصناعية دي
+
+165
+00:12:42,990 --> 00:12:48,950
+ovulation الـ ovulation result هو عبارة عن انفجار
+
+166
+00:12:48,950 --> 00:12:53,290
+للـ anterior follicle and the ovum from the ovary
+
+167
+00:12:53,290 --> 00:12:58,890
+into the .. into the special cavity located in the
+
+168
+00:12:58,890 --> 00:13:02,810
+ovary .. located in the ovary الـ ovum is not
+
+169
+00:13:02,810 --> 00:13:08,930
+ovulated as single naked as complex هذه
+
+170
+00:13:08,930 --> 00:13:12,830
+البويضة اللي بتطلع من ال Graafian follicle بفعل حدوث
+
+171
+00:13:12,830 --> 00:13:17,130
+rupture في الـ Graafian follicle rupture في الـ
+
+172
+00:13:17,130 --> 00:13:23,070
+anterior الـ anterior fluid and ovum ما بتخرج هذه
+
+173
+00:13:23,070 --> 00:13:28,210
+البويضة بشكل نيكد يعني عارية من الخلايا لأ ما بتخرج
+
+174
+00:13:28,210 --> 00:13:33,030
+single لوحدها لأ بتخرج محاطة بكمية من الخلايا تعرض
+
+175
+00:13:33,030 --> 00:13:38,830
+كالتالي تخرج عبارة عن ovum zona pellucida وهي عبارة
+
+176
+00:13:38,830 --> 00:13:44,450
+عن cell membrane as word 2 أو 3 طبقات من الكورونا
+
+177
+00:13:44,450 --> 00:13:52,010
+radiata و الـ «ماتريكس» يحتوي على «سلب الكيومولاس»
+
+178
+00:13:52,010 --> 00:13:56,770
+يعني عندي في المنتصف الـ ovum البويضة الناضجة التي
+
+179
+00:13:56,770 --> 00:14:01,310
+تُلقح يليها مباشرة من الخارج الـ zona pellucida التي
+
+180
+00:14:01,310 --> 00:14:05,850
+تعمل كـ cell membrane يليها طبقتين أو ثلاث طبقات من
+
+181
+00:14:05,850 --> 00:14:12,130
+الكورونا radiata يليها طبقة سميكة من الـ cells أو
+
+182
+00:14:12,130 --> 00:14:15,930
+الـ cumulus وهذا الـ cumulus مهم جدا نتخلص منها
+
+183
+00:14:15,930 --> 00:14:21,790
+قبل عملية ال fertilization مهم جدا نفهم أن بعض
+
+184
+00:14:21,790 --> 00:14:25,810
+السيدات وبعض الحالات أثناء عملية ال rupture أو ال
+
+185
+00:14:25,810 --> 00:14:29,590
+ovulation بيصير عند السيدة bleeding وهذا أمر طبيعي
+
+186
+00:14:29,590 --> 00:14:34,210
+جدا ال bleeding ما اتش عن تفجر ال follicular الـ
+
+187
+00:14:34,210 --> 00:14:37,010
+Graafian follicle أو تفجر ال follicle وخروج
+
+188
+00:14:37,010 --> 00:14:41,110
+البويضة فما في عندنا منه خوف طالما كان slightly بينما
+
+189
+00:14:41,110 --> 00:14:45,310
+إذا كان heavy و continuously هنا مشكلة لازم يصير
+
+190
+00:14:45,310 --> 00:14:51,150
+فيها زيارة لطبيب طبعا يرافقها ألم مستمر في منطقة ال
+
+191
+00:14:51,150 --> 00:14:55,110
+ovary خلينا نشوف الفيديو المتعلق بهذا الموضوع إيش
+
+192
+00:14:55,110 --> 00:14:59,290
+فيه يحكي على عملية ال ovulation و كيف تتم عملية ال
+
+193
+00:14:59,290 --> 00:15:03,550
+ovulation Structure
+
+194
+00:15:03,550 --> 00:15:04,490
+of Open Ovary
+
+195
+00:15:09,460 --> 00:15:13,540
+الـ ovum هو البويضة الناتجة اللي بتتطور من جرم
+
+196
+00:15:13,540 --> 00:15:17,940
+البويضات الجرثومية اللي موجودة في قشرة المبيض كل
+
+197
+00:15:17,940 --> 00:15:23,100
+جرم البويضات الجرثومية يتطور إلى عدد صغير من الجراثيم
+
+198
+00:15:23,100 --> 00:15:33,240
+يسمى Oogonia من خلال انقسامات مستمرة وتطور Oogonia
+
+199
+00:15:33,240 --> 00:15:36,940
+تتطور إلى بويضات ابتدائية ومن ثم إلى بويضات
+
+200
+00:15:36,940 --> 00:15:37,320
+ناضجة
+
+201
+00:15:40,850 --> 00:15:43,390
+هل كنت تعرف أن أولاد الحيوانات أو الحيوانات من
+
+202
+00:15:43,390 --> 00:15:49,030
+الحيوانات يمكنها أن تنزل إلى شخص جديد بداخل فترة
+
+203
+00:15:49,030 --> 00:15:52,910
+قصيرة من أيام أو أيام أو أسابيع؟ هل هذا لا
+
+204
+00:15:52,910 --> 00:15:57,990
+يجعل الحيوانات حقا مميزة في الحيوانات؟ هيا،
+
+205
+00:15:57,990 --> 00:16:01,370
+دعنا نتعرف أكثر عن أسلوب هذه الحيوانات المميزة
+
+206
+00:16:03,920 --> 00:16:08,120
+طبعا في الشق الأول اتكلم عن ال Oogonia وكيف تتطور
+
+207
+00:16:08,120 --> 00:16:12,100
+البويضات من البداية وصولا إلى ال Oocyte حاليا
+
+208
+00:16:12,100 --> 00:16:16,300
+هيتكلم عن ال structure of ovum or oocyte at the
+
+209
+00:16:16,300 --> 00:16:19,760
+end of this module you will be able to describe
+
+210
+00:16:19,760 --> 00:16:25,480
+the structure of a mature ovum structure of an
+
+211
+00:16:25,480 --> 00:16:30,460
+ovum the ovum of humans are spherical about 0.2
+
+212
+00:16:30,460 --> 00:16:35,240
+millimeters in diameter وهي موجودة مغلقة في المبيض
+
+213
+00:16:35,240 --> 00:16:41,900
+المبيض عادة موجودة واحدة في المبيض في المبيض
+
+214
+00:16:41,900 --> 00:16:45,140
+واحدة
+
+215
+00:16:45,140 --> 00:16:46,460
+من المبيض موجودة واحدة في المبيض موجودة واحدة من
+
+216
+00:16:46,460 --> 00:16:46,500
+المبيض موجودة واحدة في المبيض موجودة واحدة من
+
+217
+00:16:46,500 --> 00:16:47,320
+المبيض موجودة واحدة في المبيض موجودة واحدة من
+
+218
+00:16:47,320 --> 00:16:47,480
+المبيض موجودة واحدة في المبيض موجودة واحدة من
+
+219
+00:16:47,480 --> 00:16:50,900
+المبيض موجودة واحدة في المبيض موجودة واحدة من
+
+220
+00:16:50,900 --> 00:17:00,500
+المبيض موجودة واحدة
+
+221
+00:17:00,500 --> 00:17:05,980
+من المبيض إذن الـ cytoplasm الخاص بالـ Oocyte أو الـ
+
+222
+00:17:05,980 --> 00:17:11,120
+Ovum بنسميه O-plasm O-plasm، plasma من الـ plasma و
+
+223
+00:17:11,120 --> 00:17:15,560
+O من ال Oocyte أو ال Ovum فبنسميه O-plasm الـ
+
+224
+00:17:15,560 --> 00:17:19,120
+vesicle and the nucleolus is known as the germinal
+
+225
+00:17:19,120 --> 00:17:23,940
+spot a thick transparent envelope covering the
+
+226
+00:17:23,940 --> 00:17:28,620
+ovum is called zona striata or zona pellucida
+
+227
+00:17:29,710 --> 00:17:34,810
+والخلايا الجريبية التي تتجاوز من الفوليكل إلى الجسم
+
+228
+00:17:34,810 --> 00:17:40,270
+الخارجي تسمى كورونا رادياتا دعونا نعرف أكثر عن
+
+229
+00:17:40,270 --> 00:17:44,870
+الجزءين المختلفين من الـ ovum يلك
+
+230
+00:17:44,870 --> 00:17:50,530
+أو أوفم الوحوش من أوفم يمكن أن يكون مختلفاة إلى
+
+231
+00:17:50,530 --> 00:17:55,250
+اكسوبلازم المظهر الخارجي ايضا يسمى البرتقال الأجهزي
+
+232
+00:17:55,250 --> 00:17:59,250
+واندوبلازم المظهر الداخلي ايضا يسمى أوفم 
+
+233
+00:18:25,380 --> 00:18:28,620
+طبعا هذه التفاصيل اللي بيحكيها كلها مش مهتمين فيها
+
+234
+00:18:28,620 --> 00:18:34,590
+بشكل أساسي ولكن مهتمين بما تتكون الـ ovum الجسم
+
+235
+00:18:34,590 --> 00:18:38,310
+البشري ليس لديه الكثير من هذا اليوك المدعم الذي
+
+236
+00:18:38,310 --> 00:18:45,870
+يدفع الجسم بسرعة في تطوره، لذلك الجسم البشري يسمى
+
+237
+00:18:45,870 --> 00:18:50,550
+كـ Microlecithal لأن Microlecithal هو كلمة استخدامها
+
+238
+00:18:50,550 --> 00:18:55,490
+لتسمية أشجار صغيرة ليس لديها الكثير من اليوك جرثومي
+
+239
+00:18:55,490 --> 00:19:02,100
+الوثيقل الجسم يسمى جرثومي الوثيقالجرمن البسيكل هو
+
+240
+00:19:02,100 --> 00:19:07,500
+كبير ومركزي وفي البداية يحتوي على موقع أساسي ولكن
+
+241
+00:19:07,500 --> 00:19:11,080
+عندما يتكبر الـ ovum فهو يصبح ألا مركز في الموقع،
+
+242
+00:19:11,080 --> 00:19:15,640
+فالبويضة البشرية تحتوي على مقاومة قطبية. جزء من الـ
+
+243
+00:19:15,640 --> 00:19:21,240
+ovum مع جسمه وجسمه القطبي يسمى بـ Animal Pole وجزء
+
+244
+00:19:21,240 --> 00:19:27,540
+آخر يسمى بـ Vegetable Pole. جسم جسم الـ ovum هو
+
+245
+00:19:27,540 --> 00:19:31,370
+نفس ما يكون من جسم عضوية وهي مغلقة في محطة
+
+246
+00:19:31,370 --> 00:19:37,850
+نواة  وداخل النواة يوجد نوية مفهوم كما
+
+247
+00:19:37,850 --> 00:19:44,530
+يسمى كـ Germinal Spot غشاء النواة غشاء ضخم
+
+248
+00:19:44,530 --> 00:19:49,970
+يسمى Zona striata أو Zona pellucida غشاء النواة
+
+249
+00:19:49,970 --> 00:19:54,830
+لفترة طويلة من وقت التكوين هذا الغشاء قد يساعد في
+
+250
+00:19:54,830 --> 00:20:00,220
+الحماية في أول مرات من التكاثر الـ Corona Radiata
+
+251
+00:20:00,220 --> 00:20:04,420
+هو مجموعة من 2 أو 3 مجموعات من الخلايا التي تم تجريبها
+
+252
+00:20:04,420 --> 00:20:08,940
+من الفوليكلات هذه الخلايا تتجه إلى الوضع الخارجي
+
+253
+00:20:08,940 --> 00:20:15,880
+من الـ Zona pellucida عند إطلاقها من الفوليكلات
+
+254
+00:20:15,880 --> 00:20:20,240
+خلايا الـ Corona Radiata تم تجريبها من حول الـ
+
+255
+00:20:20,240 --> 00:20:24,100
+Zona pellucida والخلايا الأعلى من هذه المجموعة هي
+
+256
+00:20:24,100 --> 00:20:25,680
+عمودية في الشكل
+
+257
+00:20:28,620 --> 00:20:32,720
+طبعا هذه أهم المعلومات الخاصة بالـ Ovum الـ
+
+258
+00:20:32,720 --> 00:20:36,740
+Structure و الـ Ovum مهم منها الـ Zona pellucida و
+
+259
+00:20:36,740 --> 00:20:38,980
+الـ Function اللي خاصة فيها وهذا هنتكلم فيها
+
+260
+00:20:38,980 --> 00:20:43,960
+باستفاضة في محاضرات لاحقة ثم يليها الـ two أو
+
+261
+00:20:43,960 --> 00:20:48,400
+three layer من الـ corona radiata ثم يليها الـ cells
+
+262
+00:20:48,400 --> 00:20:51,480
+cumulus أو الـ cumulus cell المهم جدا في
+
+263
+00:20:51,480 --> 00:20:56,480
+عملية الحماية في عملية الحماية هذه أهم مكونات
+
+264
+00:20:57,440 --> 00:21:03,540
+الخاصة بالـ ovum ننتقل فيما بعد إلى كيف تنقل
+
+265
+00:21:03,540 --> 00:21:07,900
+البويضة كيف تنقل البويضة تحت مصطلح ovum transport
+
+266
+00:21:07,900 --> 00:21:13,400
+or egg transport the first step in egg transport
+
+267
+00:21:13,400 --> 00:21:18,300
+is capture of the ovulated egg by the fallopian
+
+268
+00:21:18,300 --> 00:21:21,980
+tube بمعنى
+
+269
+00:21:21,980 --> 00:21:26,840
+آخر أنه بمجرد خروج البويضة من الـ follicle أو من
+
+270
+00:21:26,840 --> 00:21:30,820
+الـ Graafian follicle، لازم شعيرات موجودة في نهاية
+
+271
+00:21:30,820 --> 00:21:33,800
+الـ fallopian tube تعمل catching للبويضة،
+
+272
+00:21:33,800 --> 00:21:38,380
+capturing، capture or catching shortly before
+
+273
+00:21:38,380 --> 00:21:42,820
+ovulation, the epithelial cells of the fallopian tube
+
+274
+00:21:42,820 --> 00:21:47,020
+become more highly ciliated and smooth muscles
+
+275
+00:21:47,020 --> 00:21:52,040
+activity in the tube and isthmus ligament increase as
+
+276
+00:21:52,040 --> 00:21:55,620
+the result of hormone influx بمعنى آخر إن هذه
+
+277
+00:21:55,620 --> 00:22:00,220
+العملية لازم تكون عملية متناسقة بمجرد ما البويضة
+
+278
+00:22:00,220 --> 00:22:04,220
+تصل لمرحلة ال ovulation لازم الهرمونات تأثر على
+
+279
+00:22:04,220 --> 00:22:08,000
+ال fallopian tube وعلى ال filaments و ال ligament
+
+280
+00:22:08,000 --> 00:22:12,120
+الموجودة في نهاية ال fallopian tube عشان تصير more
+
+281
+00:22:12,120 --> 00:22:16,800
+ciliated مما يساعد على حركة البويضة للداخل more
+
+282
+00:22:16,800 --> 00:22:20,360
+flexible علشان تقدر تصل للبويضة في المكان اللي
+
+283
+00:22:20,360 --> 00:22:24,760
+بده تخرج منه بمجرد خروج البويضة بتعمل catching
+
+284
+00:22:24,760 --> 00:22:28,740
+هذه الـ filament أو هذه الـ ligament لهذه البويضة و
+
+285
+00:22:28,740 --> 00:22:32,140
+بتحركها في اتجاه الداخل طب إيش اللي بيخلي الـ
+
+286
+00:22:32,140 --> 00:22:36,240
+ligament more flexible و more ciliated؟ وإيش اللي
+
+287
+00:22:36,240 --> 00:22:38,440
+بيخلي الـ smooth muscles الخاصة في الـ fallopian
+
+288
+00:22:38,440 --> 00:22:41,860
+tube more active؟ هي عبارة عن الـ hormones اللي
+
+289
+00:22:41,860 --> 00:22:45,330
+تفرز من خلال الـ anterior pituitary gland بالإضافة
+
+290
+00:22:45,330 --> 00:22:48,630
+إلى الهرمونات التي تفرز من خلال الـ ovary زي الـ
+
+291
+00:22:48,630 --> 00:22:55,970
+Estrogen ثم البيض سينتقل اتجاه اليوترس
+
+292
+00:22:55,970 --> 00:23:01,570
+أخيرًا بسبب تقلص عضلات الرحم من جزء لجزء
+
+293
+00:23:01,570 --> 00:23:01,850
+من الجزء من الجزء من الجزء من الجزء من الجزء من
+
+294
+00:23:01,850 --> 00:23:02,370
+الجزء من الجزء من الجزء من الجزء من الجزء من الجزء
+
+295
+00:23:02,370 --> 00:23:07,210
+من الجزء من الجزء من الجزء من الجزء من الجزء من
+
+296
+00:23:07,210 --> 00:23:07,430
+الجزء من الجزء من الجزء من الجزء من الجزء من الجزء
+
+297
+00:23:07,430 --> 00:23:07,450
+من الجزء من الجزء من الجزء من الجزء من الجزء من
+
+298
+00:23:07,450 --> 00:23:07,470
+الجزء من الجزء من الجزء من الجزء من الجزء من الجزء
+
+299
+00:23:07,470 --> 00:23:11,090
+من الجزء من
+
+300
+00:23:11,090 --> 00:23:14,590
+الجزء من خلال .. أو عفواً إلى الرحم من خلال
+
+301
+00:23:14,590 --> 00:23:18,130
+the fallopian tube ويتم نقله من خلال Contraction
+
+302
+00:23:18,130 --> 00:23:20,850
+Muscles الخاصة في الـ fallopian tube بالإضافة إلى
+
+303
+00:23:20,850 --> 00:23:24,370
+السيريا الموجودة في الداخل وحنشوفها كمان شوية
+
+304
+00:23:24,370 --> 00:23:29,250
+بولّت معلومة جانبية أن الـ fallopian tube أو هذه
+
+305
+00:23:29,250 --> 00:23:34,090
+الـ tube الموجودة في المبيض لأن المبيض هو عبارة عن
+
+306
+00:23:34,090 --> 00:23:38,630
+الـ ovary الـ fallopian tube و الرحم وخلافه وأنا
+
+307
+00:23:38,630 --> 00:23:42,110
+كله reproductive system والمبيض هو المنطقة اللي
+
+308
+00:23:42,110 --> 00:23:46,270
+بيصير فيها نضوج للبويضة، يليها fallopian tube اللي
+
+309
+00:23:46,270 --> 00:23:50,050
+بتنقل البويضة بعد الـ maturation و الـ ovulation إلى
+
+310
+00:23:50,050 --> 00:23:55,330
+الرحم هذه الـ tubes بتكون ciliated من الداخل، بتكون
+
+311
+00:23:55,330 --> 00:24:01,290
+مبطنة بالسيلية من الداخل، like the tubule mucosa may
+
+312
+00:24:01,290 --> 00:24:04,650
+also play a role in the egg transportation، their
+
+313
+00:24:04,650 --> 00:24:08,110
+action is not obligatory because women with
+
+314
+00:24:08,110 --> 00:24:13,410
+immotile cilia syndrome are often fertile وجدوا
+
+315
+00:24:13,410 --> 00:24:18,630
+أن الأنابيب هذه اللي بتوصل من المبيض حتى الرحم 
+
+316
+00:24:18,630 --> 00:24:23,670
+مبطنة بالداخل بالسيلية وهي كمان فيها ميوكاس هذه
+
+317
+00:24:23,670 --> 00:24:27,150
+السيلية والميوكاس بتساعد البويضة على الحركة
+
+318
+00:24:27,150 --> 00:24:31,790
+الميوكاس بتعمل كمادة تشحيم تساعد انزلاق البويضة و
+
+319
+00:24:31,790 --> 00:24:35,610
+السيلية أيضا تدفع البويضة وتسارع من عملية انزلاقها
+
+320
+00:24:35,610 --> 00:24:40,660
+وصولاً للرحم لكن عملية وجود السيلية ليس عملية
+
+321
+00:24:40,660 --> 00:24:45,100
+وحركتها ليس عملية إجبارية لأن بعض الدراسات العلمية
+
+322
+00:24:45,100 --> 00:24:49,420
+وجدت أن بعض السيدات تفتقر إلى السيلية تحت مصطلح
+
+323
+00:24:49,420 --> 00:24:54,340
+Immotile Cilia Syndrome ولكنها ما زالت قادرة على
+
+324
+00:24:54,340 --> 00:24:58,940
+الإنجاب وصنفت as fertile women or fertile female
+
+325
+00:25:00,930 --> 00:25:04,830
+عملية نقل البويضة من خلال الأنابيب التي تسمى
+
+326
+00:25:04,830 --> 00:25:09,930
+tubular transport تستغرق حوالي 3 إلى 4 أيام، يعني
+
+327
+00:25:09,930 --> 00:25:13,170
+البويضة أول ما تدخل في الـ fallopian tube بفعل
+
+328
+00:25:13,170 --> 00:25:17,010
+الـ ligament، بفعل عملية الـ catching لها، تأخذ من 3
+
+329
+00:25:17,010 --> 00:25:21,730
+إلى 4 أيام سواء كانت هذه البويضة مخصبة أو غير مخصبة
+
+330
+00:25:23,170 --> 00:25:27,230
+لأنه لو كانت مخصبة هتنزل للرحم الذي يترسب على شكل
+
+331
+00:25:27,230 --> 00:25:31,450
+embryo ولو كانت غير مخصبة هتنزل على شكل oocyte و
+
+332
+00:25:31,450 --> 00:25:37,210
+تطلع معها لـ bleeding كل fallopian tube طولها ..
+
+333
+00:25:37,210 --> 00:25:42,130
+كل fallopian tube طوله ما يقارب من 10 إلى 13 سم طب
+
+334
+00:25:42,130 --> 00:25:45,390
+الـ egg transport لها نفس الـ phase أم لها phase
+
+335
+00:25:45,390 --> 00:25:49,250
+مختلفة؟ وجد العلماء أن الـ egg transportation as a
+
+336
+00:25:49,250 --> 00:25:53,100
+process تمر بـ two phase الـ phase الأول وهو الـ
+
+337
+00:25:53,100 --> 00:25:57,840
+slowly transport و بتأخذ و بيستغرق حوالي 72 ساعة
+
+338
+00:25:57,840 --> 00:26:03,160
+يليه الـ more rapid phase و بتستغرق حوالي 8 ساعات
+
+339
+00:26:03,160 --> 00:26:06,800
+during which the egg or the embryo passes through
+
+340
+00:26:06,800 --> 00:26:11,940
+the isthmus and into the uterus يعني بمعنى آخر أن الـ
+
+341
+00:26:11,940 --> 00:26:17,700
+slowly transportation phase بيستغرق 72 ساعة وهو
+
+342
+00:26:17,700 --> 00:26:20,740
+بيقطع هذه الـ 72 ساعة بس بيقطع
+
+343
+00:26:23,770 --> 00:26:28,250
+10 إلى 13 سم أما الـ rapid phase اللي
+
+344
+00:26:28,250 --> 00:26:32,510
+بيستغرق 8 ساعات فقط لقطع المسافة ما بين الـ
+
+345
+00:26:32,510 --> 00:26:36,310
+fallopian tube و اليوترس اللي بتسميه الـ isthmus
+
+346
+00:26:36,310 --> 00:26:39,750
+أو المضيق، هنشوفه كمان شوية في الصورة if
+
+347
+00:26:39,750 --> 00:26:42,450
+fertilization has not occurred, the egg will be
+
+348
+00:26:42,450 --> 00:26:46,650
+degenerated and is phagocytosed يعني والله إذا كانت
+
+349
+00:26:46,650 --> 00:26:49,430
+البويضة ما حصل لهاش fertilization ممكن يصيبها
+
+350
+00:26:49,430 --> 00:26:51,070
+degeneration في الـ fallopian tube، وبعدين
+
+351
+00:26:51,070 --> 00:26:57,590
+phagocytosisالأخضر وظلت يصير عملية تدحرج  وصولاً
+
+352
+00:26:57,590 --> 00:27:02,550
+لليوترس هتنزل مع الـ bleeding و لكن .. و لكن .. و
+
+353
+00:27:02,550 --> 00:27:09,030
+لكن الأكثر دقة والأصح أن عمر البويضة 24 ساعة
+
+354
+00:27:09,030 --> 00:27:13,550
+فبالتالي طالما هي 24 ساعة هتتموت في الفلوبيان تيوب 
+
+355
+00:27:13,550 --> 00:27:18,190
+وهو تتحرك بعد 24 ساعة يعني بعد يوم ما حصلش
+
+356
+00:27:18,190 --> 00:27:24,590
+fertilization هتستغرق لنقلها للإزمس 72 ساعة أخذت من
+
+357
+00:27:24,590 --> 00:27:30,670
+الـ 72 ساعة لـ 24 ساعة ليه؟ as half-life عشان
+
+358
+00:27:30,670 --> 00:27:38,530
+تتلقح أو ما تتلقحش ما تلقحتش لسه دا لها كمان 24 و
+
+359
+00:27:38,530 --> 00:27:43,370
+24 فبالتالي بيصير لها عملية degradation يعني ما
+
+360
+00:27:43,370 --> 00:27:47,150
+وصلتش لـ rapid phase يعني بيصير عملية degradation
+
+361
+00:27:47,150 --> 00:27:50,810
+برجع بأكد مرة ثانية إن البويضة تستقر في الـ
+
+362
+00:27:50,810 --> 00:27:54,930
+fallopian tube 24 ساعة الـ half-life حقها 24
+
+363
+00:27:54,930 --> 00:28:00,330
+ساعة بعد 24 ساعة ما صار لهاش عملية تلقيح لهذه
+
+364
+00:28:00,330 --> 00:28:03,890
+البويضة البويضة مباشرة بيصيبها degradation وبعدين
+
+365
+00:28:03,890 --> 00:28:09,250
+phagocytosis طب ليش ما بتكمل؟ لأن عملية إكمالها
+
+366
+00:28:09,250 --> 00:28:13,290
+للوصول إلى اليوترس بتحتاج إلى 72 ساعة من الـ 72
+
+367
+00:28:13,290 --> 00:28:16,210
+ساعة اختصرت في الـ 24 ساعة عشان بس يصيبها
+
+368
+00:28:16,210 --> 00:28:19,720
+fertilization ولا لا، حصل لها fertilization بتكمل أو
+
+369
+00:28:19,720 --> 00:28:24,280
+بتقطع، ما حصل لهاش بتصير self-degradation أو بعد كده
+
+370
+00:28:24,280 --> 00:28:28,540
+phagocytosis هذا الشكل اللي احنا بنحكي عنه، هذا الـ
+
+371
+00:28:28,540 --> 00:28:32,620
+ligament هنا اللي طبعاً المبيض وهذه الـ fimbria
+
+372
+00:28:32,620 --> 00:28:38,600
+الفوليكل وصلت لـ diameter أكثر من 18 مليمتر الفوليكل،
+
+373
+00:28:38,600 --> 00:28:41,460
+يعني دا دليل إن هو mature؟ بيبدأ يصير عملية الـ
+
+374
+00:28:41,460 --> 00:28:44,640
+ovulation، خروج البويضة الـ ligament هذه اللي
+
+375
+00:28:44,640 --> 00:28:47,200
+موجودة في نهاية الـ fallopian tube نفسها بتكون flexible
+
+376
+00:28:47,850 --> 00:28:54,850
+ciliated و قادرة على الـ contraction فبتعمل
+
+377
+00:28:54,850 --> 00:28:59,390
+catching أو capturing للـ oocyte أو للـ ova لازم
+
+378
+00:28:59,390 --> 00:29:02,750
+يصلها fertilization في هذه المنطقة في الثلث الأول
+
+379
+00:29:02,750 --> 00:29:06,310
+أو الربع الأول من الـ fallopian tube طبعاً السيلية ماشية
+
+380
+00:29:06,310 --> 00:29:11,450
+تقطع هذه العملية كلها تحتاج 72 ساعة عشان تدخل
+
+381
+00:29:11,450 --> 00:29:14,570
+المضيق هذا وهي المنطقة التي تفصل الـ fallopian tube
+
+382
+00:29:14,570 --> 00:29:21,600
+عن اليوترس تقدرها 8 ساعات في أول 24 ساعة هي
+
+383
+00:29:21,600 --> 00:29:24,520
+فرصتها للـ fertilization بعد كده يصيبها degradation
+
+384
+00:29:24,520 --> 00:29:29,920
+و elimination ما بتكمل للآخر ما بتكمل للآخر خلينا
+
+385
+00:29:29,920 --> 00:29:35,180
+نشوف الفيديو اللي بحكي في هذا الموضوع كيف تنتقل
+
+386
+00:29:35,180 --> 00:29:39,760
+البويضة أيضاً ovulation is the release of an egg from
+
+387
+00:29:39,760 --> 00:29:42,640
+one of the ovaries it often happens about midway
+
+388
+00:29:42,640 --> 00:29:45,260
+through the menstrual cycle although the exact
+
+389
+00:29:45,260 --> 00:29:48,980
+timing may vary. In preparation for ovulation, the
+
+390
+00:29:48,980 --> 00:29:51,520
+lining of the uterus, or endometrium, thickens.
+
+391
+00:29:52,160 --> 00:29:55,080
+The pituitary gland in the brain stimulates one of
+
+392
+00:29:55,080 --> 00:29:58,260
+the ovaries to release an egg. The wall of the
+
+393
+00:29:58,260 --> 00:30:00,820
+ovarian follicle ruptures at the surface of the
+
+394
+00:30:00,820 --> 00:30:04,740
+ovary. The egg is released. Finger-like structures
+
+395
+00:30:04,740 --> 00:30:07,500
+called fimbriae sweep the egg into the neighboring
+
+396
+00:30:07,500 --> 00:30:12,160
+fallopian tube. الـ fimbria سماه هنا finger-like
+
+397
+00:30:12,160 --> 00:30:15,490
+structure البويضة بتسير من خلال الـ fallopian tube
+
+398
+00:30:15,490 --> 00:30:17,670
+تحركها بشكل أكبر من التعبيرات في أعضاء الـ
+
+399
+00:30:17,670 --> 00:30:22,230
+fallopian tube هنا في الـ fallopian tube البويضة
+
+400
+00:30:22,230 --> 00:30:27,050
+يمكن أن تكون مجرد مجرد مجرد مجرد مجرد مجرد مجرد
+
+401
+00:30:27,050 --> 00:30:27,350
+مجرد مجرد مجرد مجرد مجرد مجرد مجرد مجرد مجرد مجرد
+
+402
+00:30:27,350 --> 00:30:27,690
+مجرد مجرد مجرد مجرد مجرد مجرد مجرد مجرد مجرد مجرد
+
+403
+00:30:27,690 --> 00:30:36,530
+مجرد مجرد مجرد مجرد
+
+404
+00:30:36,530 --> 00:30:41,630
+مجرد
+
+405
+00:30:42,010 --> 00:30:45,250
+طبعاً بيحكيلي إذا الـ oocyte صار لها fertilization في
+
+406
+00:30:45,250 --> 00:30:49,090
+الـ fallopian tube، هيصير لها عملية division بشكل
+
+407
+00:30:49,090 --> 00:30:52,750
+مستمر جداً، هتتكون لـ cluster أو complex من
+
+408
+00:30:52,750 --> 00:30:57,790
+الخلايا، تبدأ بالزيجوت، بعد كده هتبدأ تستمر رحلتها
+
+409
+00:30:57,790 --> 00:31:02,010
+وصولاً إلى اليوترس When the zygote reaches the
+
+410
+00:31:02,010 --> 00:31:04,790
+uterus, it implants in the lining of the uterus,
+
+411
+00:31:04,970 --> 00:31:06,250
+and pregnancy begins.
+
+412
+00:31:13,720 --> 00:31:18,800
+معلومة مهمة جداً البويضة إن خُصّبت هتستمر في عملية
+
+413
+00:31:18,800 --> 00:31:22,840
+الانقسام المتتالي لوصول إلى عدد كبير جداً من
+
+414
+00:31:22,840 --> 00:31:27,460
+الخلايا اللي هتعبر الـ isthmus وصولاً إلى الرحم و
+
+415
+00:31:27,460 --> 00:31:31,160
+تنغمس فيه بداية لتكوين الجنين ولكن ذكروا في
+
+416
+00:31:31,160 --> 00:31:35,340
+الفيديو إذا البويضة لم تخصب سوف يصير يحدث عملية
+
+417
+00:31:35,340 --> 00:31:41,530
+degradation و self degradation و phagocytosis أو
+
+418
+00:31:41,530 --> 00:31:45,710
+self absorption قبل ما تصل اليوترس بمعنى آخر قبل
+
+419
+00:31:45,710 --> 00:31:58,750
+ما تدخل الإزماس في أول 72 ساعة طبعاً
+
+420
+00:32:06,570 --> 00:32:09,510
+بعد .. بعد هذه العملية ما تخلص و ما تصير الدورة الشهرية 
+
+421
+00:32:09,510 --> 00:32:13,550
+fertilization بسفوعين تكمل الدورة تبدأ ودورة شهرية
+
+422
+00:32:13,550 --> 00:32:18,270
+جديدة نسميها menstruation أو الدورة الشهرية
+
+423
+00:32:18,270 --> 00:32:23,870
+هذا بالنسبة لعملية انتقال البويضة من لحظة تخليقها
+
+424
+00:32:23,870 --> 00:32:29,580
+ونضوجها مرورا بوصولها إلى الرحم أو بنقاط الرحمنجي
+
+425
+00:32:29,580 --> 00:32:33,680
+لشقة تانية المتعلقة بالـ Male Gametes وهو عبارة عن
+
+426
+00:32:33,680 --> 00:32:37,620
+الـ spermatozoa تحت أنواع sperm transportation أو 
+
+427
+00:32:37,620 --> 00:32:41,000
+الـ transport the sperm transport occur in both
+
+428
+00:32:41,000 --> 00:32:43,820
+male reproductive tract and female reproductive
+
+429
+00:32:43,820 --> 00:32:47,020
+tract يعني ما بقدر أقول إن عملية نقل الجاميتات
+
+430
+00:32:47,020 --> 00:32:50,220
+الذكرية فقط تحدث في ال reproductive system للذكر
+
+431
+00:32:50,220 --> 00:32:53,440
+لأ في كمان تحدث في reproductive systemللأنثى
+
+432
+00:32:53,440 --> 00:32:57,260
+وتكون الأصعب لأن ال sperm في داخل ال
+
+433
+00:32:57,260 --> 00:33:01,330
+reproductive system للأنثى هي عبارة عن رحلة
+
+434
+00:33:01,330 --> 00:33:06,350
+محفوفة بالمخاطر وصولا إلى مكان تلقيح البويضة في
+
+435
+00:33:06,350 --> 00:33:09,450
+الـ Fallopian tube هنعرف أيش المخاطر والصعوبات
+
+436
+00:33:09,450 --> 00:33:12,770
+اللي بواجهتها الـ sperm انتقالا من منطقة الفيجاينة
+
+437
+00:33:12,770 --> 00:33:16,410
+حتى وصولا إلى الـ Fallopian tube in the male
+
+438
+00:33:16,410 --> 00:33:19,350
+reproductive tract, transport of spermatozoa is
+
+439
+00:33:19,350 --> 00:33:22,870
+closely connected with their structural and
+
+440
+00:33:22,870 --> 00:33:28,000
+functional maturation يعني ينتقل ال sperm في الـ 
+مكان التصنيع لمكان التخزين ثم Ejaculation في
+
+441
+00:33:28,000 --> 00:33:31,180
+الخارج بينما .. فبالتالي البيئة واحدة .. البيئة
+
+442
+00:33:31,180 --> 00:33:35,260
+واحدة خاصة بال reproductive system and the male
+
+443
+00:33:35,260 --> 00:33:38,540
+البيئة واحدة خاصة بالتصنيع والنضوج والتخزين ما فيش
+
+444
+00:33:38,540 --> 00:33:43,440
+أي مخاطر عليه إلا إذا كان بيكون self-antibody ضده
+
+445
+00:33:43,440 --> 00:33:47,980
+In female reproductive tract it is important for
+
+446
+00:33:47,980 --> 00:33:52,220
+spermatozoa to pass or transport to the upper
+
+447
+00:33:52,220 --> 00:33:55,920
+uterine tube where they can meet with oocyte to
+
+448
+00:33:55,920 --> 00:34:01,390
+fertilize مهم جدا بالنسبة للـ reproductive tract
+
+449
+00:34:01,390 --> 00:34:04,770
+أن الـ sperm يقطع مسافة خطرة ومحفوفة بالمخاطر من
+
+450
+00:34:04,770 --> 00:34:09,530
+بداية الـ cervix حتى وصولا إلى الأنابيب الفلوب يلتقي
+
+451
+00:34:09,530 --> 00:34:14,350
+هناك مع البويضة لكي يحدث عملية ال fertilization
+
+452
+00:34:14,350 --> 00:34:16,930
+بعد ما يصير عملية الـ spermatogenesis في
+
+453
+00:34:16,930 --> 00:34:20,670
+seminiferous tubule يُنقل الحيوان المنوي أو النطفة إلى الـ
+
+454
+00:34:20,670 --> 00:34:25,870
+epididymis من أجل التخزين والنضوج أثناء عملية نقله
+
+455
+00:34:25,870 --> 00:34:32,070
+يكون هذا الـ sperm mature but are non-motile يعني
+
+456
+00:34:32,070 --> 00:34:40,130
+خلال عملية تصنيعه إلى حد ما وعملية نقله يكون 
+
+457
+00:34:40,130 --> 00:34:46,250
+mature already ولكن non-functional، non-motile
+
+458
+00:34:46,250 --> 00:34:50,330
+unable for fertilizationمهم جدا أن هذا الـ sperm
+
+459
+00:34:50,330 --> 00:34:56,180
+صار mature و ينقل إلى الـ epididymis لكي يخزن و
+
+460
+00:34:56,180 --> 00:35:02,320
+يحدث له عملية ال functionality بمعنى أخر اكتساب
+
+461
+00:35:02,320 --> 00:35:07,000
+القدرة على الحركة من خلال طباول الفلاجلة واكتساب
+
+462
+00:35:07,000 --> 00:35:14,680
+قدرته على إخصاب البويضة بعد ال spermatozoa تنتقل من ال
+
+463
+00:35:14,680 --> 00:35:18,860
+seminal vesicleإلى الـ epididymis بطريقة معينة
+
+464
+00:35:18,860 --> 00:35:22,980
+تسمى الـ passive transportation ال passive
+
+465
+00:35:22,980 --> 00:35:25,580
+transportation يعني عبارة عن عملية لا تحتاج إلى
+
+466
+00:35:25,580 --> 00:35:28,680
+طاقة فبالتالي الشول بيخليها تنقل ببساطة to the
+
+467
+00:35:28,680 --> 00:35:34,700
+head of the epididymis يعني في بعض ال fluid يفرز
+
+468
+00:35:34,700 --> 00:35:40,120
+يساعد في نقل ال sperm اللي mature بعد ما صُنّى في
+
+469
+00:35:40,120 --> 00:35:44,560
+ال seminiferous tubule ينقل من ال seminiferous tubule to الhead
+
+470
+00:35:44,560 --> 00:35:48,200
+of the epididymisالـ epididymis منطقة مهمة جدًا
+
+471
+00:35:48,200 --> 00:35:51,960
+للتخزين والـ functionality الخاصة من الـ sperm
+
+472
+00:35:51,960 --> 00:35:55,480
+طبعًا الـ sperm حوالي بستغرق 12 يوم in the high
+
+473
+00:35:55,480 --> 00:36:00,120
+equivalent duct of the epididymis which measured 60
+
+474
+00:36:00,120 --> 00:36:05,240
+meter in the human during which they undergo
+
+475
+00:36:05,240 --> 00:36:09,520
+biochemical maturation يعني الـ epididymis هذا طوله
+
+476
+00:36:09,520 --> 00:36:13,780
+حوالي 6 مترالحيوان المنوي يستقر فيه ويستغرق فيه 6
+
+477
+00:36:13,780 --> 00:36:18,360
+أيام 12 يوم 6 متر يستغرق الحيوان المنوي فيه 12 يوم
+
+478
+00:36:18,360 --> 00:36:23,500
+خلال 12 يوم يكتسب الحيوان المنوي القدرة العالية على التطور
+
+479
+00:36:23,500 --> 00:36:29,760
+والنضوج بالشكل الكامل تحت مصطلح biochemical
+
+480
+00:36:29,760 --> 00:36:35,480
+maturation شو يحصل في هذه العملية
+
+481
+00:36:35,480 --> 00:36:39,080
+أول شغلة بيصير فيها من الـ maturation أو الـ 
+
+482
+00:36:45,640 --> 00:36:48,040
+exchange أو الـ variation أن هناك بعض التغيرات
+
+483
+00:36:48,040 --> 00:36:50,840
+التي تحدث على الـ glycoprotein الموجود في الـ cell
+
+484
+00:36:50,840 --> 00:36:54,620
+membrane أو الـ plasma membrane الخاصة بالـ head
+
+485
+00:36:54,620 --> 00:36:57,240
+sphere by the time spermatozoa have arrived at the
+
+486
+00:36:57,240 --> 00:37:02,000
+tail of the epididymis they are capable of
+
+487
+00:37:02,000 --> 00:37:05,480
+fertilizing it بعد هذه الاثناشر يوم ما تبدأ تمضي
+
+488
+00:37:10,430 --> 00:37:14,010
+بشكل أو بآخر تبدأ الحيوانات المنوية في الوصول إلى
+
+489
+00:37:14,010 --> 00:37:17,810
+نهاية الـ epididymis دليل على أنها اكتسبت القدرة
+
+490
+00:37:17,810 --> 00:37:24,290
+على الحركة والقدرة على عملية التخصيب لذا سوف تنطلق
+
+491
+00:37:24,290 --> 00:37:27,670
+لكي تؤدي الوظيفة المطلوبة منها من خلال عملية
+
+492
+00:37:27,670 --> 00:37:31,030
+بتسميها ال ejaculation ال ejaculation هي عبارة عن
+
+493
+00:37:31,030 --> 00:37:38,600
+عملية خروج المني من الإنسان إلى الـ cervix أو
+
+494
+00:37:38,600 --> 00:37:43,920
+الفرجية الـ sperm will be rapidly passed through
+
+495
+00:37:43,920 --> 00:37:51,560
+the vas deferens and are mixed with the fluid
+
+496
+00:37:51,560 --> 00:37:55,360
+secretion from the seminal vesicle and prostatic
+
+497
+00:37:55,360 --> 00:37:59,320
+gland لحظة ال ejaculation يتم نقل الحيوانات
+
+498
+00:37:59,320 --> 00:38:02,760
+المنوية أو النطف الذكرية بفعل ال vas deferens
+
+499
+00:38:02,760 --> 00:38:09,980
+للخارج ولكنها تنقل للخارج لوحدها لأ تنقل خليط مع
+
+500
+00:38:09,980 --> 00:38:15,380
+ال fluid الذي يفرز من ال seminal vesicles بالإضافة
+
+501
+00:38:15,380 --> 00:38:18,680
+للبرستاتيكي كلها يعني ال seminal fluid اللي هناخده
+
+502
+00:38:18,680 --> 00:38:22,660
+مستقبلا في محاضرة خاصة فيه هو عبارة عن خليط من ال
+
+503
+00:38:22,660 --> 00:38:27,290
+spermatozoa النطف الذكرية وال fluid يخرج من منطقة
+
+504
+00:38:27,290 --> 00:38:31,530
+ثانية منطقة لها علاقة بالـ seminal vesicles النبيب
+
+505
+00:38:31,530 --> 00:38:35,710
+المنوي ومنطقة تسمى ال prostatic gland غدة
+
+506
+00:38:35,710 --> 00:38:39,270
+البرستاتا طبعا ال prostatic fluid اللي يخرج من
+
+507
+00:38:39,270 --> 00:38:43,690
+البرستاتا غني ببعض المواد زي ال citric acid زي
+
+508
+00:38:43,690 --> 00:38:48,070
+الacidic phosphatase زي الزنك وزي المغنيسيوم بينما
+
+509
+00:38:48,070 --> 00:38:50,990
+الفلويد اللي بيخرج من ال seminal vesicle غني
+
+510
+00:38:50,990 --> 00:38:56,220
+بالفركتوز والفركتوز يعتبر من أهم مصادر الطاقة
+
+511
+00:38:56,220 --> 00:39:00,940
+الخاصة بالحيوان المنوي بالإضافة إلى الفركتوز بيكون خاص
+
+512
+00:39:00,940 --> 00:39:04,000
+فيه مادة أخرى ال prostaglandin يعني similar to
+
+513
+00:39:04,000 --> 00:39:07,920
+physical بيخرج fluid الفلويد غني بالفركتوز و
+
+514
+00:39:07,920 --> 00:39:11,350
+للپروستاجلاندينالـ prostatic gland أو الـ
+
+515
+00:39:11,350 --> 00:39:14,890
+prostatic gland تخرج fluid غني بالزنك و ال citric
+
+516
+00:39:14,890 --> 00:39:19,650
+acid و الفوسفاتيز و الماغنيسيوم طب سؤالي لماذا
+
+517
+00:39:19,650 --> 00:39:22,710
+يستخدم ال sperm ال fructose ولا يستخدم الجلوكوز
+
+518
+00:39:22,710 --> 00:39:27,410
+لأن احتراق الجلوكوز أسرع من احتراق الجليكوز
+
+519
+00:39:27,410 --> 00:39:33,930
+وبالتالي طالما ال sperm يتحرك بسرعة هائلة فبيحتاج
+
+520
+00:39:33,930 --> 00:39:38,630
+إلى كمية كبيرة من الطاقة تحرق بسرعة أضف إلى ذلك إنه
+
+521
+00:39:38,630 --> 00:39:44,230
+إن الـ sperm الـ cell يمتلك بعض الإنزيمات
+
+522
+00:39:44,230 --> 00:39:47,750
+المسؤولة عن ال consuming للجلوكوز واستهلاك
+
+523
+00:39:47,750 --> 00:39:51,470
+الجلوكوز ومن أشهرها ال Exokinase for example فما
+
+524
+00:39:51,470 --> 00:39:56,170
+بيقدر يستخدم الجلوكوز فبيستخدم ال fructose أسرع في
+
+525
+00:39:56,170 --> 00:40:01,950
+الاحتراق وتماشى مع الإنزيمات التي يمتلكها صورة
+
+526
+00:40:01,950 --> 00:40:07,310
+بتوضح الكلام اللي أنا حكيته من خلالالـ Testes وهي
+
+527
+00:40:07,310 --> 00:40:11,750
+المصنع الخاص بتصنيع الحيوانات المنوية أو النطف
+
+528
+00:40:11,750 --> 00:40:15,230
+الذكرية في منطقة سميها Seminiferous tubule يتم
+
+529
+00:40:15,230 --> 00:40:17,970
+نقلها إلى الـ epididymis عن طريق الـ Passive
+
+530
+00:40:17,970 --> 00:40:22,210
+Transportation الـ epididymis في الـ Head يبقى 12
+
+531
+00:40:22,210 --> 00:40:24,590
+يوم من أجل عملية الـ Maturation و الـ
+
+532
+00:40:24,590 --> 00:40:29,230
+Functionality بعدين بيصل لـ epididymis ينتقل من خلال
+
+533
+00:40:29,230 --> 00:40:33,550
+ما يُعرف باسم الـ Vas Deferens إلى قناة الـ
+
+534
+00:40:33,550 --> 00:40:37,870
+Ejaculation قناة الخروج أو قناة القلب في الـ Vas
+
+535
+00:40:37,870 --> 00:40:41,970
+Deferens يتم خلطه بـ Fluid تأتي جزء من الـ
+
+536
+00:40:41,970 --> 00:40:45,890
+Prostatic Fluid و Fluid آخر يأتي من الـ Seminal
+
+537
+00:40:45,890 --> 00:40:50,390
+Vesicle طبعا هذه الـ Fluid مهمة جدا في حماية الـ
+
+538
+00:40:50,390 --> 00:40:54,290
+Spermatozoa وفي تغذية الـ Spermatozoa في حماية و
+
+539
+00:40:54,290 --> 00:40:58,050
+تغذية الـ Spermatozoa يعني ديش الـ sperm بيقعد في
+
+540
+00:40:58,050 --> 00:41:03,750
+limited mass 12 يوم أو أسبوعين على حد أقصى الـ
+
+541
+00:41:03,750 --> 00:41:06,550
+Sperm Maturation in epididymis شو بيصير في الـ
+
+542
+00:41:06,550 --> 00:41:09,930
+sperm من Maturation أو variation في الـ epididymis
+
+543
+00:41:09,930 --> 00:41:13,810
+أول حاجة بيكتسب القدرة على ال progressive motility
+
+544
+00:41:13,810 --> 00:41:17,090
+ولما أقول progressive motility يعني الحركة التي
+
+545
+00:41:17,090 --> 00:41:20,970
+تحدث في اتجاه واحد وبشكل مستقيم progressive
+
+546
+00:41:20,970 --> 00:41:25,870
+motility بيزيد قدرته على تخصيب البويضة بيعمل
+
+547
+00:41:25,870 --> 00:41:29,610
+change في مادة البروتين الموجودة داخل ال sperm
+
+548
+00:41:29,610 --> 00:41:34,680
+فبيخلي ال sperm تتخرج Maturation of Acrosome والـ
+
+549
+00:41:34,680 --> 00:41:37,640
+Acrosome باكل بيحتوى على كمية كبيرة جدا من الـ
+
+550
+00:41:37,640 --> 00:41:40,880
+lytic enzyme أو الإنزيمات الهاضمة التي تساعد في
+
+551
+00:41:40,880 --> 00:41:43,980
+عملية ال penetration بيعمل تغيير في الـ plasma
+
+552
+00:41:43,980 --> 00:41:48,180
+membrane بيخلّي ال sperm أكثر ملائمة لعملية ال
+
+553
+00:41:48,180 --> 00:41:54,180
+fertilizationباكتسب الـ sperm قدرة على امتلاك
+
+554
+00:41:54,180 --> 00:41:57,960
+مستقبلات خاصة بالـ zona pellucida يعني بمعنى آخر
+
+555
+00:41:57,960 --> 00:42:00,800
+بيصير more specific أنه يرتبط بالـ zona pellucida
+
+556
+00:42:00,800 --> 00:42:06,300
+الموجودة as outer layer خاصة بالـ oocyte بدونها
+
+557
+00:42:06,300 --> 00:42:09,640
+مش هيقدر يتعرف على هذا الريسيبتور increased
+
+558
+00:42:09,640 --> 00:42:13,900
+disulfide bond between the nucleoprotein وهذا الـ
+
+559
+00:42:13,900 --> 00:42:17,120
+disulfide bond بتخليه more stable بيخلي البروتين
+
+561
+00:42:17,120 --> 00:42:21,840
+أو بيخلي المادة الورقية more stable تقوم المواد
+
+562
+00:42:21,840 --> 00:42:25,300
+وتقوم العقبات اللي هتواجهها في عملية انتقالها
+
+563
+00:42:25,300 --> 00:42:27,140
+للفلوجيا من الـ tube عندما تصل إلى الـ
+
+564
+00:42:27,140 --> 00:42:31,020
+reproductive system الخاص بالفيميل فال stability
+
+565
+00:42:31,020 --> 00:42:36,400
+بتصير أعلى accumulation of manosalate residue on
+
+566
+00:42:36,400 --> 00:42:41,300
+the acrosome plasma membrane طبعا هذا أيضا بيخليها
+
+567
+00:42:41,300 --> 00:42:46,600
+more stable في عملية الانتقال في عملية الانتقال
+
+568
+00:42:48,000 --> 00:42:50,820
+طبعا message of sperm through the female
+
+569
+00:42:50,820 --> 00:42:55,660
+reproductive tract is regularity to maximum of its
+
+570
+00:42:55,660 --> 00:42:58,360
+chance of fertilization and ensure that sperm with
+
+571
+00:42:58,360 --> 00:43:02,640
+normal morphology and motility will be once to
+
+572
+00:43:02,640 --> 00:43:06,060
+success يعني نقل ال sperm خلال ال reproductive
+
+573
+00:43:06,060 --> 00:43:10,960
+system لازم نحافظ على ال sperm بكامل هيئته، بكامل 
+
+574
+00:43:10,960 --> 00:43:15,630
+نشاطه، بكامل حيويته، بكامل وظيفته الحفاظ على الـ
+
+575
+00:43:15,630 --> 00:43:20,650
+sperm بكامل هذه المؤشرات يساعد على زيادة فرصة ال
+
+576
+00:43:20,650 --> 00:43:25,770
+fertilization مما يساعد على حدوث الحمل والحصول على
+
+577
+00:43:25,770 --> 00:43:30,310
+بيبي أو إمبريو the sperm are subject to physical
+
+578
+00:43:30,310 --> 00:43:34,350
+stress during ejaculation and contraction of the
+
+579
+00:43:34,350 --> 00:43:38,720
+female tract and they may be oxidative يعني بمعنى
+
+580
+00:43:38,720 --> 00:43:41,480
+آخر خلال عملية الـ ejaculation في ال reproductive
+
+581
+00:43:41,480 --> 00:43:45,980
+system الخاص بالفيميل بسبب بواجه كمية كبيرة جدا من
+
+582
+00:43:45,980 --> 00:43:50,120
+المعوقات والمخاطر أولهم ال stress ال physical
+
+583
+00:43:50,120 --> 00:43:53,360
+stress الناتج عن اختلاف ال environment ما بين ال
+
+584
+00:43:53,360 --> 00:43:56,100
+reproductive system الخاص بالفيميل و reproductive
+
+585
+00:43:56,100 --> 00:43:59,660
+system الخاص بالميل أو ما يُعرف اسم ال
+
+586
+00:43:59,660 --> 00:44:02,640
+reproductive tract male reproductive tract أو
+
+587
+00:44:02,640 --> 00:44:05,650
+female reproductive tract أضف إلى ذلك الـ
+
+588
+00:44:05,650 --> 00:44:08,990
+contraction الخاص بالـ female tract الـ female
+
+589
+00:44:08,990 --> 00:44:11,730
+tract الخاص بالـ reproductive tract عند الفميل
+
+590
+00:44:11,730 --> 00:44:14,770
+فيها contraction مختلفة عن ال contraction الموجودة
+
+591
+00:44:14,770 --> 00:44:18,730
+عند المال فبالتالي هذا يكبر أحد المخاطر والصعوبات
+
+592
+00:44:18,730 --> 00:44:22,430
+اللي بوجهها ال sperm أضف إلى ذلك ال oxidative
+
+593
+00:44:22,430 --> 00:44:27,530
+damage بفعل اختلاف ال pH واختلاف المواد الموجودة
+
+594
+00:44:27,530 --> 00:44:33,360
+عند الفميل عن المال because sperm are allogenic to
+
+595
+00:44:33,360 --> 00:44:38,820
+female they may be prepared and activated the
+
+596
+00:44:38,820 --> 00:44:46,740
+immune system باختلاف الطبيعة الـ sperm عن الهيئة
+
+597
+00:44:46,740 --> 00:44:49,900
+أو خلّيني أقول عن البيئة الخاصة بال reproductive
+
+598
+00:44:49,900 --> 00:44:55,440
+system عند ال female الجهاز المناعي اللي عند ال
+
+599
+00:44:55,440 --> 00:44:59,480
+female بيتعرف على ال sperm كأنه abnormal or
+
+600
+00:44:59,480 --> 00:45:03,710
+foreign substance فبحث الجهاز المناعة مما يؤدي إلى
+
+601
+00:45:03,710 --> 00:45:08,510
+تدميره علشان كده بلاقي دايما ال normal sperm count
+
+602
+00:45:08,510 --> 00:45:13,390
+تكون بالملايين علشان لو صار فيه reduction في ال
+
+603
+00:45:13,390 --> 00:45:17,390
+count الخاص بال sperm أثناء نقله من ال .. في خلال
+
+604
+00:45:17,390 --> 00:45:20,150
+ال reproductive .. female reproductive tract
+
+605
+00:45:20,150 --> 00:45:25,110
+transportation process يظل في عندي عدد يكفي لعملية
+
+606
+00:45:25,110 --> 00:45:29,110
+ال fertilization during intercourses or coitus
+
+607
+00:45:32,600 --> 00:45:35,780
+the upper vagina to grow close to the cervix يعني
+
+608
+00:45:35,780 --> 00:45:39,980
+خلال عملية الإبتصال كل sperm أو كل السيمن بيقع في
+
+609
+00:45:39,980 --> 00:45:43,560
+منطقة معينة تعرف باسم ال upper vagina وهي عبارة عن
+
+610
+00:45:43,560 --> 00:45:47,220
+منطقة قريبة جدا من ال cervix وهو عنق الرحم اللذي
+
+611
+00:45:47,220 --> 00:45:50,640
+يعتبر بوابة ال reproductive system الخاصة بال
+
+612
+00:45:50,640 --> 00:45:55,980
+female the normal environment of vagina is unstable
+
+613
+00:45:55,980 --> 00:46:03,620
+for sperm لأنها تقريبا أقل من خمسة pH أقل من خمسة
+
+614
+00:46:03,620 --> 00:46:07,680
+فبالتالي الـ pH الخاصة بالفيجاينة و الخاصة
+
+615
+00:46:07,680 --> 00:46:13,500
+بالفيميل تكون أقل من خمسة pH فالي انستابل للسبرم
+
+616
+00:46:13,500 --> 00:46:17,300
+فلا تساعد على بقاء السبرم بالشكل الحي أو بالشكل
+
+617
+00:46:17,300 --> 00:46:22,080
+المطلوب مما يؤدي إلى ثلاث كمية كبيرة جدا و عدد
+
+618
+00:46:22,080 --> 00:46:28,730
+كبير جدا من السبرم the lower pH of vagina is a
+
+619
+00:46:28,730 --> 00:46:31,970
+protective mechanism for women against many
+
+620
+00:46:31,970 --> 00:46:35,350
+sexually transmitted pathogens يعني بمعنى أخر هذه
+
+621
+00:46:35,350 --> 00:46:38,630
+الـ pH الأقل من خالصها ما بيكون بشكل عشوائي وشكل
+
+622
+00:46:38,630 --> 00:46:42,150
+غير مدروس لأ، مهم جدا عشان يحمي ال reproductive
+
+623
+00:46:42,150 --> 00:46:45,790
+system الخاص بالفيميل من ال sexually transmitted
+
+624
+00:46:45,790 --> 00:46:49,730
+disease sexually transmitted disease، so this pH
+
+625
+00:46:49,730 --> 00:46:52,630
+working like fires حواجز
+
+626
+00:46:55,050 --> 00:47:01,870
+مجرّات مباشرة شهدت أنه في 10 ثانية من إدارة الحركة
+
+627
+00:47:01,870 --> 00:47:10,150
+الحركة العقلية ترتفع من 4.3 إلى 7.2 وهذا يجعل الـ
+
+628
+00:47:10,150 --> 00:47:13,830
+sperm أكثر قدرة على البقاء وبكسب قدرة على الحركة
+
+629
+00:47:13,830 --> 00:47:17,150
+بقولك بعد الـ ejaculation ووصول الحركة الحركة
+
+630
+00:47:17,150 --> 00:47:20,710
+العقلية إلى أعلى جزء الحركة العقلية مقابل الحركة
+
+631
+00:47:20,710 --> 00:47:27,420
+العقلية مباشرة احسب عشر ثواني تبدأ البيئة الخاصة
+
+632
+00:47:27,420 --> 00:47:31,340
+بالفيجاينال بـH تتغير فتصبح من خمسة إلى سبعة
+
+633
+00:47:31,340 --> 00:47:35,700
+واثنين وهي عبارة عن بيئة مناسبة لبقاء ال sperm
+
+634
+00:47:35,700 --> 00:47:39,760
+واكتسابه قدرة على الحركة يعني كأنه بتفعل عملية
+
+635
+00:47:39,760 --> 00:47:43,720
+الحركة لل sperm بتصير ال sperm عنده قدرة ورغبة في
+
+636
+00:47:43,720 --> 00:47:48,260
+الحركة بدل ما كان عنده غير قادر على الحركة وممكن
+
+637
+00:47:48,260 --> 00:47:52,540
+يصيله destruction بشكل أو بآخر الـ optimal pH للـ
+
+638
+00:47:52,540 --> 00:48:00,020
+sperm motility تقدر من 6 ل 6.5 6 ل 6.5 خلال دقائق
+
+639
+00:48:00,020 --> 00:48:03,080
+بعد دخول الفجاية .. ده دخول الـ semen للفجاية
+
+640
+00:48:03,080 --> 00:48:07,380
+الخاصة بالفمان the human semen will be coagulated
+
+641
+00:48:07,380 --> 00:48:11,760
+into loose gel شو يعني loose gel؟ أن الـ semen
+
+642
+00:48:11,760 --> 00:48:16,420
+بيكون عبارة عن كتل بفعل عمليات التجلط الموجودة فيه
+
+643
+00:48:16,420 --> 00:48:20,060
+طبعا هذه التجلطات الموجودة بتحميه خلال انتقاله من
+
+644
+00:48:20,060 --> 00:48:24,740
+الـ Reproductive Tract للألمان وصولا إلى الـ
+
+645
+00:48:24,740 --> 00:48:28,620
+Cervix طبعا بيبدأ هذا الكواجوليت يسيله عملية إذابة
+
+646
+00:48:28,620 --> 00:48:32,380
+علشان يتحرر ال sperm إيش يعني إذابة؟ الكواجوليت
+
+647
+00:48:32,380 --> 00:48:36,920
+عبارة عن شبكة تحمل ال sperm من أي خطر ممكن يواجهه
+
+648
+00:48:36,920 --> 00:48:41,170
+خلال عملية الانتقال وعلشان ال sperm يتحررويبدأ
+
+649
+00:48:41,170 --> 00:48:46,270
+يتحرك، لازم يصير تفكك لهذا الخيوط تحت حاجة نسميها
+
+650
+00:48:46,270 --> 00:48:53,530
+«Lose the Gel» «الكواجولان» يحمي الـ Sperm من مجال
+
+651
+00:48:53,530 --> 00:48:56,930
+الـ «ميكروعينفيرومنت» الـ Harsh Vaginal ويمكن
+
+652
+00:48:56,930 --> 00:49:00,450
+أيضا تحمي الـ Sperm قريبًا من الـ Serum إيش وظيفة
+
+653
+00:49:00,450 --> 00:49:04,470
+الكواجولان أو التجلطات أو التخثرات الموجودة في الـ
+
+654
+00:49:04,470 --> 00:49:10,520
+seminal؟ هي عبارة عن عوامل تحمي الـ sperm من أي up
+
+655
+00:49:10,520 --> 00:49:16,180
+-normality موجودة في الفيجاينة و تعمل على إيصال ال
+
+656
+00:49:16,180 --> 00:49:21,600
+sperm إلى طرف ال cervical بكفاءة عالية و بدرجة
+
+657
+00:49:21,600 --> 00:49:27,240
+عالية من الأمام
+
+658
+00:49:27,240 --> 00:49:31,840
+سوف نكتفي على هذا الحد في مهدد المحاضرة على أمل أن
+
+659
+00:49:31,840 --> 00:49:36,100
+نكمل في المحاضرة القادمة إن شاء الله أرجو أن
+
+660
+00:49:36,100 --> 00:49:39,010
+تكونوا دائما بخير  تروحوا سالمين
+
+
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Z4YwVN8UPs8.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Z4YwVN8UPs8.srt
new file mode 100644
index 0000000000000000000000000000000000000000..482f8119322aba3e897a2fb2289789f7f20f6191
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Z4YwVN8UPs8.srt
@@ -0,0 +1,2699 @@
+1
+00:00:01,530 --> 00:00:05,430
+بسم الله الرحمن الرحيم الصلاة والسلام على أشرف
+
+2
+00:00:05,430 --> 00:00:10,270
+المرسلين سيدنا محمد الصادق الأمين  أما بعد بداية
+
+3
+00:00:10,270 --> 00:00:14,090
+أرحب بكم جميعا  جديدًا وأرجو من الله الكريم أن 
+
+4
+00:00:14,090 --> 00:00:18,960
+تكونوا جميعا بخير و بصحة جيدة في المحاضرة السابقة
+
+5
+00:00:18,960 --> 00:00:23,680
+تطرقنا إلى عدة نقاط أهمها الـ infertility problem
+
+6
+00:00:23,680 --> 00:00:29,040
+تعريف ال infertility كيف تصنف ال infertility هل
+
+7
+00:00:29,040 --> 00:00:34,060
+تعتبر ال infertility أو التأثير في الإنجاب مشكلة 
+
+8
+00:00:34,060 --> 00:00:39,680
+يعاني منها جميع الناس أم فيها معينة؟ تحدثنا عن 
+
+9
+00:00:39,680 --> 00:00:43,320
+أسباب ال infertility عند ال male و عند ال female
+
+10
+00:00:43,320 --> 00:00:48,490
+تحدثنا عن العوامل التي تؤثر على ال fertility أي
+
+11
+00:00:48,490 --> 00:00:52,270
+الخصوبة عند ال male و عند ال female و فيما سبق
+
+12
+00:00:52,270 --> 00:00:58,210
+تحدثنا عن ال IVF و تحدثنا عن ال IGC  وكان  حديثًا بسيطًا
+
+13
+00:00:58,210 --> 00:01:05,110
+عنه و توقفنا عند مصطلح جديد كيف يمكن الحصول على 
+
+14
+00:01:05,110 --> 00:01:12,780
+baby أو كيف يمكن الحصول على حالة من الإنجاب تحت
+
+15
+00:01:12,780 --> 00:01:18,140
+عنوان getting ready for pregnancy كيف يحدث الحمل
+
+16
+00:01:18,140 --> 00:01:24,760
+عند ال female وكيف يساهم نطف الرجل أو ال male على 
+
+17
+00:01:24,760 --> 00:01:28,720
+الإنجاب هنتكلم هلأ عدة أمور هنتكلم على ال
+
+18
+00:01:28,720 --> 00:01:33,780
+spermogenesis هنتكلم عن ال oogenesis كتعريفهما
+
+19
+00:01:33,780 --> 00:01:39,750
+ والأحداث التي تصير في كلا العمليتين كيف تساهم عملية الـ
+
+20
+00:01:39,750 --> 00:01:43,770
+sperm metagenesis والتخليق النطف الذكرية في الحصول 
+
+21
+00:01:43,770 --> 00:01:50,370
+على sperm mature قادر أن يخصب بويضة ناضجة هذه 
+
+22
+00:01:50,370 --> 00:01:54,530
+البويضة تتحول إلى جنين، هذا الجنين يصبح
+
+23
+00:01:54,530 --> 00:02:00,240
+implantation في جدار الرحم للوصول إلى مولود كامل
+
+24
+00:02:00,240 --> 00:02:05,780
+بعد تسعة أشهر أو سبعة أشهر يناير على الحالة الخاصة 
+
+25
+00:02:05,780 --> 00:02:11,600
+بالأنثى أو السيدة في نقاط بسيطة إن شاء الله سنتكلم
+
+26
+00:02:11,600 --> 00:02:17,500
+عن getting pregnancy بداية عملية ال pregnancy ليست
+
+27
+00:02:17,500 --> 00:02:22,200
+عملية سهلة بل هي عبارة عن عملية معقدة جدا جدا جدا
+
+28
+00:02:22,200 --> 00:02:27,240
+تمر بعدة مراحل و عدة أحداث و يشارك فيها الرجل
+
+29
+00:02:27,720 --> 00:02:32,780
+وتشارك فيها السيدة كلًا بجاميطته المقصود 
+
+30
+00:02:32,780 --> 00:02:36,300
+بالجاميطات ال female gametes هي عبارة عن ال oocyte
+
+31
+00:02:36,300 --> 00:02:42,020
+و لازم تكون ضمن صفات معينة ومواصفات معينة حتى ضمن
+
+32
+00:02:42,020 --> 00:02:46,400
+Diameter معين وجاميطات الذكر اللي بنسميها male 
+
+33
+00:02:46,400 --> 00:02:49,400
+gametes هي عبارة عن ال sperm و هذا ال sperm لازم
+
+34
+00:02:49,400 --> 00:02:53,600
+يكون completely normal أو بنسبة معينة طبعًا لما
+
+35
+00:02:53,600 --> 00:02:56,700
+نقول normal لما نحكي عن ال sperm من حيث ال
+
+36
+00:02:56,700 --> 00:02:59,760
+morphology أما  لنحكي على الـ semen و هنتكلم عنه بشكل
+
+37
+00:02:59,760 --> 00:03:04,260
+مُفصّل لازم يكون normal من حيث الـ count من حيث ال
+
+38
+00:03:04,260 --> 00:03:08,940
+motility و من حيث ال morphology علشان يصير في عنده
+
+39
+00:03:08,940 --> 00:03:12,880
+pregnancy و ال pregnancy should be  pregnancy لازم
+
+40
+00:03:12,880 --> 00:03:17,240
+يصير عنده fusion ما بين ال sperm ال خاص بال male
+
+41
+00:03:17,240 --> 00:03:21,900
+مع ال oocyte الخاصة بال female وهذه عملية ال
+
+42
+00:03:21,900 --> 00:03:26,550
+fusion أو ال fertilization بالمصطلح العلمي تحدث في
+
+43
+00:03:26,550 --> 00:03:29,730
+منطقة معينة من ال reproductive system عند الفيميل
+
+44
+00:03:29,730 --> 00:03:34,090
+وهي عبارة عن ال fallopian tube أو reproductive
+
+45
+00:03:34,090 --> 00:03:38,810
+tract إذا صار في عندي fusion يعني صار في عندي أول 
+
+46
+00:03:38,810 --> 00:03:42,910
+خطوة من خطوات ال pregnancy وعلشان يصير في عندي
+
+47
+00:03:42,910 --> 00:03:47,270
+pregnancy لازم يصير عندي steps أول حاجة both male
+
+48
+00:03:47,270 --> 00:03:51,290
+and female sex cell should be or must be passed
+
+49
+00:03:51,290 --> 00:03:57,310
+through a long series of exchanges وهي اللي بنسميها
+
+50
+00:03:57,310 --> 00:04:01,510
+gametogenesis بمعنى آخر أنه أنا عندي male gametes و
+
+51
+00:04:01,510 --> 00:04:05,130
+female gametes هذه ال male و ال female gametes لازم
+
+52
+00:04:05,130 --> 00:04:08,810
+أن يصير فيها عملية maturation للوصول إلى ال
+
+53
+00:04:08,810 --> 00:04:13,030
+formula أو ال form اللي بسمح لها بعملية التلقيح
+
+54
+00:04:13,030 --> 00:04:18,230
+هذه ال exchange اللي بتصير بنسميها gametogenesis أي
+
+55
+00:04:18,230 --> 00:04:23,820
+تخليق الجاميتات تخليق عفواً بنسميها Gametogenesis هي 
+
+56
+00:04:23,820 --> 00:04:27,940
+عبارة عن تخليق الجميطات  نسميها Gametogenesis وهي
+
+57
+00:04:27,940 --> 00:04:33,160
+عبارة عن عملية يتم فيها تحويل وتخليق الجميطات و لكي
+
+58
+00:04:33,160 --> 00:04:36,420
+تخلق الجميطات ال male و ال female gametes لازم
+
+59
+00:04:36,420 --> 00:04:40,660
+يصير في عندك convert لهم في ال genetic material في 
+
+60
+00:04:40,660 --> 00:04:46,020
+ال phenotype و تبقى structure عشان تصل لمرحلة جاميط وإذا 
+
+61
+00:04:46,020 --> 00:04:50,580
+وصلت لمرحلة جاميط معناها سوف تكون قادرة حتماً على ال
+
+62
+00:04:50,580 --> 00:04:54,500
+fertilization بشرط أن تكون Normal من حيث الـ
+
+63
+00:04:54,500 --> 00:04:57,420
+Function لأن في عندي بعض الجميطات زي الـ Oocyte
+
+64
+00:04:57,420 --> 00:05:03,140
+جميط أو الـ spermatozoite أو الـ spermatozoa أو
+
+65
+00:05:03,140 --> 00:05:08,480
+الـ sperm بتكون phenotypically normal ولكن 
+
+66
+00:05:08,480 --> 00:05:12,020
+functionally abnormal فما بتقدر تعمل ال
+
+67
+00:05:12,020 --> 00:05:15,240
+fertilization هذه ال spermatozoa أو ال oocyte ما
+
+68
+00:05:15,240 --> 00:05:19,640
+بتقدر تستمر بعد عملية ال fertilization هذه إذا
+
+69
+00:05:19,640 --> 00:05:23,910
+كانت functionally غير طبيعية المرحلة الثانية من
+
+70
+00:05:23,910 --> 00:05:29,070
+المراحل وهي عبارة عن بعد عملية الـ Gametogenesis
+
+71
+00:05:29,070 --> 00:05:34,370
+عملية التخليق لازم هذه الجميطات تنتقل من مكان
+
+72
+00:05:34,370 --> 00:05:38,770
+التخليق إلى مكان النضوج فبالتالي نستطيع أن نستوعب
+
+73
+00:05:38,770 --> 00:05:42,330
+و نفهم شيء هنا أن الـ place of production should
+
+74
+00:05:42,330 --> 00:05:45,290
+be separated from the place of storage and
+
+75
+00:05:45,290 --> 00:05:49,330
+maturation فبالتالي معناه أن الجميطات تخلق في مكان
+
+76
+00:05:49,800 --> 00:05:54,740
+وتنضج في مكان وتُخزن في مكان آخر أو تستخدم في 
+
+77
+00:05:54,740 --> 00:05:59,800
+التخصيب في مكان آخر فلو أنا أجهز على سبيل المثال على
+
+78
+00:05:59,800 --> 00:06:05,300
+الجاميطات الخاصة أو الـ Gametocyte الخاصة بالفيميل 
+
+79
+00:06:05,300 --> 00:06:10,180
+هلاجيها تُخلق في ال ovary و بيصير لها maturation في 
+
+80
+00:06:10,180 --> 00:06:13,440
+ال ovary ولكن بيصير لها fertilization في ال 
+
+81
+00:06:13,440 --> 00:06:17,400
+fallopian tube فبالتالي مكان ال maturation حتى في 
+
+82
+00:06:17,400 --> 00:06:20,870
+ال ovary مكان ال maturation يختلف عن مكان الـ 
+
+83
+00:06:20,870 --> 00:06:24,610
+formation لو أنا أتكلمت على الـ spermatocyte 
+
+84
+00:06:24,610 --> 00:06:28,210
+هلاجيها تخلق في الـ testis وتنضج في الـ embedded 
+
+85
+00:06:28,210 --> 00:06:32,510
+muscle وهو جوز من الـ testis تُخلق في منطقة في الـ 
+
+86
+00:06:32,510 --> 00:06:36,750
+testis، عن كلام أنا بالصورة و ثم بعد ذلك بيصير لها
+
+87
+00:06:36,750 --> 00:06:42,230
+ejaculation خارج جسم الإنسان علشان تستخدم في عملية
+
+88
+00:06:42,230 --> 00:06:46,170
+تلقيح البويضة الناضجة بـ fallopian tube هذه رحلة 
+
+89
+00:06:46,170 --> 00:06:51,470
+طويلة جداً يتم فيها انتقال ال sperm من ال male إلى
+
+90
+00:06:51,470 --> 00:06:54,370
+ال female لتلقح البويضة واحنا نتكلم عنها بشكل
+
+91
+00:06:54,370 --> 00:06:57,890
+واضح جداً طب ليش هنتكلم عن هذا الموضوع؟ لأنه لازم
+
+92
+00:06:57,890 --> 00:07:01,790
+نفهم ال gametogenesis كيف تخلّق أي خلل في تخليق
+
+93
+00:07:01,790 --> 00:07:06,030
+الجميطة  معناه فشل في ال fertilization فشل في ال
+
+94
+00:07:06,030 --> 00:07:11,990
+fertilization يعني غير .. غير قادرين على الحصول 
+
+95
+00:07:11,990 --> 00:07:17,720
+على حالة من حالة pregnancy بالنسبة للموضوع الواضح
+
+96
+00:07:17,720 --> 00:07:23,940
+أن الوضع 
+
+97
+00:07:23,940 --> 00:07:26,820
+يتنصف بالنسبة للموضوع الواضح أن الوضع يتنصف
+
+98
+00:07:26,820 --> 00:07:26,920
+بالنسبة للموضوع الواضح ان الوضع يتنصف بالنسبة
+
+99
+00:07:26,920 --> 00:07:26,980
+للموضوع الواضح ان الوضع يتنصف بالنسبة للموضوع
+
+100
+00:07:26,980 --> 00:07:28,800
+الواضح ان الوضع يتنصف بالنسبة للموضوع الواضح ان
+
+101
+00:07:28,800 --> 00:07:30,520
+الوضع يتنصف بالنسبة للموضوع الواضح ان الوضع يتنصف
+
+102
+00:07:30,520 --> 00:07:33,320
+بالنسبة للموضوع الواضح ان الوضع يتنصف بالنسبة
+
+103
+00:07:33,320 --> 00:07:37,100
+للموضوع الواضح ان الوضع يتنصف بالنسبة للموضوع
+
+104
+00:07:37,100 --> 00:07:42,970
+الواضح ان الـأي Oocyte بعد عملية التخصيب لازم
+
+105
+00:07:42,970 --> 00:07:47,650
+تُنقل بفعل السيليا على سبيل المثال بفعل انقباضات 
+
+106
+00:07:47,650 --> 00:07:51,510
+لعضلات اللي خاصة بال reproductive tract و ال
+
+107
+00:07:51,510 --> 00:07:54,870
+fallopian tube تنتقل من منطقة التلقيح و هي
+
+108
+00:07:54,870 --> 00:07:59,210
+fallopian tube فنشوف صورة في هذه عملية التلقيح
+
+109
+00:07:59,210 --> 00:08:02,970
+البويضة animation من منطقة التلقيح fallopian tube
+
+110
+00:08:02,970 --> 00:08:07,150
+إلى الرحم لكي تنغرز في بطانة الرحم تحت مصطلح 
+
+111
+00:08:07,150 --> 00:08:13,420
+بتسميه implantation هو عبارة عن انغراس أو الانغماس 
+
+112
+00:08:13,420 --> 00:08:17,120
+فبيصير في عندي انغماس البويضة الملقحة في بطانة الرحم
+
+113
+00:08:17,120 --> 00:08:21,200
+والأم فيما بعد بتمدها أو الدورة الدموية الخاصة 
+
+114
+00:08:21,200 --> 00:08:24,360
+بالأم بتمدها بكل المواد الغذائية لتكوين ال 
+
+115
+00:08:24,360 --> 00:08:29,900
+placenta التي تعتبر مصدر ومدخل للغذاء ال 
+
+116
+00:08:29,900 --> 00:08:33,760
+gametogenesis هل هي عبارة عن حدث واحد فقط لغير one
+
+117
+00:08:33,760 --> 00:08:37,960
+event one step ولا في different steps؟ وهل ال male و
+
+118
+00:08:37,960 --> 00:08:41,780
+female gametogenesis مختلفين؟ أكيد مختلفين، لكن
+
+119
+00:08:41,780 --> 00:08:45,700
+لكي نبسط المعلومة، بما نستطيع أن نقول إن ال male 
+
+120
+00:08:45,700 --> 00:08:50,100
+gametogenesis similar with female
+
+121
+00:08:50,100 --> 00:08:55,680
+gametogenesis في only one phase؟ هل هناك أطوار 
+
+122
+00:08:55,680 --> 00:08:59,540
+أخرى؟ أكيد في عندي أربع أطوار أو أربع مراحل لتكوين
+
+123
+00:08:59,540 --> 00:09:03,380
+ال gametocyte أو ال gametogenesis العملية المرحلة
+
+124
+00:09:03,380 --> 00:09:07,500
+الأولى بنسميها extra-embryonic origin أو origin
+
+125
+00:09:07,500 --> 00:09:11,600
+of the germ cell and their migration into gonads
+
+126
+00:09:11,600 --> 00:09:17,180
+وهي عبارة عن عملية يتم فيها تخليق الجميطات في ال
+
+127
+00:09:17,180 --> 00:09:20,920
+embryo اللي بنسميها extra embryonic ليش سموها 
+
+128
+00:09:20,920 --> 00:09:25,380
+extra embryonic؟ لأنها بتحدث خارج أو قبل تكوين ال
+
+129
+00:09:25,380 --> 00:09:29,640
+embryo بالشكل اللي احنا بنعرفه ثم بعد ذلك يتم
+
+130
+00:09:29,640 --> 00:09:34,320
+نقلها إلى منطقة الجناد في ناس تعرفها بمنطق آخر هي
+
+131
+00:09:34,320 --> 00:09:38,240
+عبارة .. بمنطق آخر هي عبارة عن تصنيع الجميطات في
+
+132
+00:09:38,240 --> 00:09:42,940
+غير مكانها يعني المفروض الجميل كالـ sperm يُصنع في
+
+133
+00:09:42,940 --> 00:09:46,660
+الـ testis وكالـ oocyte تُصنع في الـ ovary ولكن 
+
+134
+00:09:46,660 --> 00:09:51,140
+أول مرحلة بنتسموها extra-embryonic وهي عبارة عن
+
+135
+00:09:51,140 --> 00:09:55,500
+عملية يتم فيها تصنيع الجميطات خارج منطقة الجنادى 
+
+136
+00:09:55,500 --> 00:09:58,380
+الجنادى اللي بنتسميه ال reproductive system للـ
+
+137
+00:09:58,380 --> 00:10:02,000
+male أو reproductive system لل female ال ovary و
+
+138
+00:10:02,000 --> 00:10:06,450
+ال testis هذه المرحلة الأولى وهذه المرحلة تتشابه 
+
+139
+00:10:06,450 --> 00:10:09,990
+عند الـ Male وعند الـ Female يليها ثلاث مراحل،
+
+140
+00:10:09,990 --> 00:10:13,610
+المرحلة الثانية زيادة في عدد الـ Germ Cells 
+
+141
+00:10:13,610 --> 00:10:18,750
+استخدام انقسام ميتوزي يليه reduction in the 
+
+142
+00:10:18,750 --> 00:10:22,530
+chromosome number في الأنثى والذكر تحت انقسام 
+
+143
+00:10:22,530 --> 00:10:26,370
+ميوزي وآخر الـ phase بنسميه Structural and
+
+144
+00:10:26,370 --> 00:10:30,130
+Functional Maturation of the Oocyte and Sperm أربع
+
+145
+00:10:30,130 --> 00:10:35,380
+خطوات الأولى هي عبارة عن تخليق الجاميط خارج منطقة
+
+146
+00:10:35,380 --> 00:10:40,440
+الجناد بالسمية Extra-Empirionic Origin وهي تتشابه
+
+147
+00:10:40,440 --> 00:10:44,760
+عند الذكر والأنثى، الـ three step الأخيرة تختلف عند
+
+148
+00:10:44,760 --> 00:10:48,460
+الذكر عن الأنثى وهي عبارة عن increase in the
+
+149
+00:10:48,460 --> 00:10:52,580
+number of germ cells من القسم الميتوزي reduction in
+
+150
+00:10:52,580 --> 00:10:55,840
+the chromosome number من القسم الميوزي وبعدين
+
+151
+00:10:55,840 --> 00:10:59,020
+structural and functional maturation of the oocyte
+
+152
+00:10:59,020 --> 00:11:04,700
+بأكد مرة أخرى أن الثلاث خطوات الأخيرة تختلف عند ال
+
+153
+00:11:04,700 --> 00:11:08,760
+male وعند ال female بينما الخطوة الأولى متشابهة
+
+154
+00:11:08,760 --> 00:11:13,160
+عند الذكر والأنثى، نيجي للخطوة خطوة، الخطوة الأولى
+
+155
+00:11:13,160 --> 00:11:17,920
+اللي سميناها Extra Embryonic Origin and Migration
+
+156
+00:11:17,920 --> 00:11:23,520
+of Germ Cells to the Gonadal Place في خلية بنسميها
+
+157
+00:11:23,520 --> 00:11:27,640
+الخلية الأم زي الخلية الـ stem cell في خلايانا
+
+158
+00:11:27,640 --> 00:11:31,690
+جميعا في خلية أم بنسميها Stem Cell ولكن الخلية
+
+159
+00:11:31,690 --> 00:11:36,130
+الأم الخاصة بالجاميط عند الذكر وعند الأنثى بنسميها
+
+160
+00:11:36,130 --> 00:11:41,450
+PGS Primordial Germ Cell من اسم الجيرم سيل ولكن 
+
+161
+00:11:41,450 --> 00:11:45,150
+ضافوا لها Primordial لأنها خلية الأم، هذه الخلية
+
+162
+00:11:45,150 --> 00:11:48,170
+الأم اللي بنسميها Primordial Germ Cell واختصارها
+
+163
+00:11:48,170 --> 00:11:53,390
+PGS هي عبارة عن الخلية الأولى التي تظهر خلال عملية
+
+164
+00:11:53,390 --> 00:11:57,510
+تكوين الجاميط، فبنسميها Precursor Cell for Gamete
+
+165
+00:11:57,510 --> 00:12:01,930
+Formation أو Precursor Cell for Gamete هذه الخلايا
+
+166
+00:12:01,930 --> 00:12:07,610
+الـ PGS تظهر خارج الجناد وبعد أن تتكاثر بأعداد
+
+167
+00:12:07,610 --> 00:12:11,930
+مناسبة بيصير لها Migration لمنطقة الجناد وهذه 
+
+168
+00:12:11,930 --> 00:12:15,870
+العملية بتصير في الـ early embryonic development في
+
+169
+00:12:15,870 --> 00:12:21,930
+الـ early embryonic development وهي أول شهور الحمل
+
+170
+00:12:21,930 --> 00:12:27,010
+على سبيل المثال حمل الذكر أو أنثى طبعا بيصير في
+
+171
+00:12:27,010 --> 00:12:32,680
+عين دي Primordial Germ Cells تبدأ تظهر في منطقة خارج
+
+172
+00:12:32,680 --> 00:12:37,900
+الجناد ثم عندما تكثر من حيث العدد تنتقل إلى منطقة 
+
+173
+00:12:37,900 --> 00:12:41,800
+الجناد Human Primordial Germ Cells first become
+
+174
+00:12:41,800 --> 00:12:47,720
+pretty recognizable at 24 days after fertilization
+
+175
+00:12:47,720 --> 00:12:52,420
+يعني ببدأ أتعرف على هذه الـ Primordial Germ Cells
+
+176
+00:12:52,420 --> 00:12:56,590
+بعد 24 يوم من الـ fertilization لو صار فيها في عندي 
+
+177
+00:12:56,590 --> 00:13:00,830
+Fertilization Aid 1، 2، 3 لحد اليوم الـ 24 بعد اليوم 
+
+178
+00:13:00,830 --> 00:13:05,690
+الـ 24 تبدأ Primordial Germ Cells تظهر وببدأ أنا
+
+179
+00:13:05,690 --> 00:13:10,450
+أتعرف عليها in the endodermal layer of the yolk sac
+
+180
+00:13:10,450 --> 00:13:14,570
+يوك ساك زي المحي، بنسميه المحي من اللغة العربية
+
+181
+00:13:14,570 --> 00:13:18,190
+طبعا بتكون في الـ size .. من حيث الـ size Very Large
+
+182
+00:13:18,190 --> 00:13:22,940
+بتحتوي هذه الخلايا على كمية كبيرة جدا من الجليكوجين
+
+183
+00:13:22,940 --> 00:13:26,320
+وبعض الإنزيمات زي الـ Alkaline Phosphatase طبعا هذا
+
+184
+00:13:26,320 --> 00:13:29,240
+الجليكوجين بيحافظ على شكلها ويحميها والـ Alkaline
+
+185
+00:13:29,240 --> 00:13:32,960
+Phosphatase بيلعب دور كبير جدا في الـ metabolic الـ
+
+186
+00:13:32,960 --> 00:13:36,680
+process الخاصة بهذه الخلايا، طبعا عملوا دراسة على
+
+187
+00:13:36,680 --> 00:13:40,760
+الماوس كـ Model وجدوا أنه فيه عنده حوالي 100 Cell
+
+188
+00:13:40,760 --> 00:13:44,540
+موجودة أو تغادر، خليني أسمي الـ Yolk Sac 100 Cell
+
+189
+00:13:44,540 --> 00:13:48,730
+من الـ Primordial Germ Cells تغادر الـ Yolk Sac وبتخضع
+
+190
+00:13:48,730 --> 00:13:51,150
+لإنقسام الميتوزي المتكرر بيصير عندنا 
+
+191
+00:13:51,150 --> 00:13:56,630
+Multiplication حوالي 6 إلى 7 مرات، الخلية بتصل
+
+192
+00:13:56,630 --> 00:14:01,210
+إلى 4000 خلية من حيث العدد وهذه بنسميها 4000
+
+193
+00:14:01,210 --> 00:14:04,630
+Primordial Germ Cells will be entered the 
+
+194
+00:14:04,630 --> 00:14:09,890
+Embryonic Colon هذه الخلايا من دراسة حدثت على
+
+195
+00:14:09,890 --> 00:14:13,310
+الفقاريات وجدوا أن الخلايا من الـ Primordial Germ 
+
+196
+00:14:13,310 --> 00:14:18,240
+Cells موجودة في هذه المنطقة أو تنتقل، خليني أسميها
+
+197
+00:14:18,240 --> 00:14:22,540
+من منطقة الـ Yolk Sac إلى منطقة الجناد، ولكن قبل أن
+
+198
+00:14:22,540 --> 00:14:27,080
+تنتقل لازم تخضع إلى انقسام الميتوزي حوالي 7 مرات
+
+199
+00:14:27,080 --> 00:14:32,940
+عشان يصل عددها إلى 4000 خلية، هذه الـ 4000 خلية هي 
+
+200
+00:14:32,940 --> 00:14:37,020
+اللي بتدخل في منطقة الـ Embryonic جناد اللي بنسميها 
+
+201
+00:14:37,020 --> 00:14:42,220
+Primitive أو Embryonic Gonad علشان تبدأ تصنع الجناد
+
+202
+00:14:43,460 --> 00:14:46,800
+عشان تبدأ تصنع الجناد الخاصة بالـ Membrane تيجي
+
+203
+00:14:46,800 --> 00:14:49,300
+المرحلة الثانية، طبعا هذه المرحلة Similar in Male
+
+204
+00:14:49,300 --> 00:14:52,540
+and Female المرحلة الثانية هي Increasing the
+
+205
+00:14:52,540 --> 00:14:56,180
+number of Germ Cells by Mitosis بعد ما تصل
+
+206
+00:14:56,180 --> 00:14:59,640
+لـ Primordial Germ Cells الأربع ألاف خلية، تصل
+
+207
+00:14:59,640 --> 00:15:03,960
+للجناد، Primordial Germ Cells Begin a phase of 
+
+208
+00:15:03,960 --> 00:15:07,180
+rapidly Mitotic Proliferation أول ما تصل 
+
+209
+00:15:07,180 --> 00:15:10,900
+الـ Primordial Germ Cells إلى الجناد تبدأ في عملية
+
+210
+00:15:10,900 --> 00:15:14,720
+الانقسام الميتوزي المتكرر عشان يزيد العدد لأن 
+
+211
+00:15:14,720 --> 00:15:18,220
+البيض في الأرض مش هيكفي، فبالتالي لازم يصير زيادة
+
+212
+00:15:18,220 --> 00:15:20,960
+في العدد، زيادة في العدد معناه أنه لازم يصير في
+
+213
+00:15:20,960 --> 00:15:24,300
+عنده انقسام ميتوزي وعارفين أن انقسام الميتوزي من 
+
+214
+00:15:24,300 --> 00:15:27,620
+المحاضرة السابقة ومن المعلومات السابقة اللي كنا
+
+215
+00:15:27,620 --> 00:15:31,140
+بنعرفها أن كل خلية بتدخل في انقسام الميتوزي تعطي 
+
+216
+00:15:31,140 --> 00:15:36,770
+خليتين متطابقتين بنسميهم Two Daughter Cells في الـ 
+
+217
+00:15:36,770 --> 00:15:41,590
+Mitotic Division، كل خلية تعطي 2 Diploid Progen
+
+218
+00:15:41,590 --> 00:15:44,910
+that are Genetically Equal، عشان كده بنسميهم 
+
+219
+00:15:44,910 --> 00:15:47,930
+Daughter Cells، تبقى إيش يعني Diploid؟ يعني فيها
+
+220
+00:15:47,930 --> 00:15:51,610
+أزواج من الكروموزوم، إذا كان أنا في الخلية الأصلية
+
+221
+00:15:51,610 --> 00:15:54,710
+فيها عندي اتنين كروموزوم، فبتعطيني خليتين كل خلية
+
+222
+00:15:54,710 --> 00:15:58,390
+فيها اتنين كروموزوم، Diploid، الـ Diploid منصف 
+
+223
+00:15:58,390 --> 00:16:04,960
+لعدد الكروموزوم طبعا بعد انقسام ميتوزي بشكل مستمر
+
+224
+00:16:04,960 --> 00:16:08,700
+وبشكل متتالي للـ Primordial Germ Cells اتصل من
+
+225
+00:16:08,700 --> 00:16:12,660
+Hundred أو Thousand إلى مليون لأن وجودنا مية خلية
+
+226
+00:16:12,660 --> 00:16:16,800
+في الفئران انقسموا انقسام ميتوزي ووصلوا أربعة آلاف
+
+227
+00:16:16,800 --> 00:16:19,300
+للأربعة آلاف انتقلوا إلى الـ Primordial Germ Cells
+
+228
+00:16:19,300 --> 00:16:21,740
+إلى الـ Gonad Place اللي بنسميها Embryonic Gonad
+
+229
+00:16:21,740 --> 00:16:25,220
+طبعا هذه تستمر في انقسام الميتوزي عشان تصل
+
+230
+00:16:25,220 --> 00:16:28,950
+للملايين الخلايا هل هي الـ Primordial Germ Cells لها
+
+231
+00:16:28,950 --> 00:16:31,850
+علاقة بالـ Oocyte والـ Spermatocyte؟ أكيد عشان
+
+232
+00:16:31,850 --> 00:16:34,690
+كده لازم تصير ملايين عشان هتخدم الـ Male والـ
+
+233
+00:16:34,690 --> 00:16:37,730
+Female طيلة فترة حياته من الخمسين أو الستين أو 
+
+234
+00:16:37,730 --> 00:16:41,810
+السبعين سنة، طبعا في الـ Mitotic Proliferation في 
+
+235
+00:16:41,810 --> 00:16:44,650
+بعض الـ Different Marks عند الـ Male وعند الـ Female
+
+236
+00:16:44,650 --> 00:16:48,710
+Germ Cells هنتكلم عنها يعني كيف الـ Male بتختلف عن
+
+237
+00:16:48,710 --> 00:16:51,850
+الـ Female أو كيف الـ Male يختلف عن الـ Female في 
+
+238
+00:16:51,850 --> 00:16:55,610
+الانقسام الميتوزي هنتكلم عنه في Mark معين وSite
+
+239
+00:16:55,610 --> 00:17:01,720
+معين بداية الـ Mitotic Active Germ Cells في الـ Female
+
+240
+00:17:01,720 --> 00:17:06,220
+بنسميها Oogonia يعني الخلايا اللي دخلت القسم 
+
+241
+00:17:06,220 --> 00:17:11,200
+الميتوزي عند الـ Female وصارت بالملايين بنسميها Oogonia
+
+242
+00:17:11,200 --> 00:17:16,500
+which is going through a period of mitotic 
+
+243
+00:17:16,500 --> 00:17:19,840
+activity in the embryonic ovary from the second
+
+244
+00:17:19,840 --> 00:17:24,280
+month to the fifth month of pregnancy in the
+
+245
+00:17:24,280 --> 00:17:28,330
+human اللي بتفهمه من هذه العبارة إن الـ Oogonia
+
+246
+00:17:28,330 --> 00:17:34,050
+تستمر في الانقسام الميتوزي من الشهر الثاني لعمر 
+
+247
+00:17:34,050 --> 00:17:38,210
+الجنين حتى الشهر الخامس بعد كده مافيش حاجة اسمها
+
+248
+00:17:38,210 --> 00:17:41,750
+Oogonia أو بمعنى آخر بعد كده بتتوقف الانقسام
+
+249
+00:17:41,750 --> 00:17:45,290
+الميتوزي إذا بالنسبة للـ Female وهذا أول نقاط 
+
+250
+00:17:45,290 --> 00:17:49,090
+الاختلاف ما بين الـ Male والـ Female في الحدث
+
+251
+00:17:49,090 --> 00:17:54,100
+الثاني أو الـ Phase الثاني من تكوين الجاميطات إن الـ 
+
+252
+00:17:54,100 --> 00:17:59,520
+Female تستمر عملية الانقسام الميتوزي بشكل تبدأ في
+
+253
+00:17:59,520 --> 00:18:03,240
+الشهر الثاني من الحمل أو الشهر الثاني من عمر 
+
+254
+00:18:03,240 --> 00:18:08,000
+الجنين حتى الشهر الخامس يعني بمجرد الجنين يدخل 
+
+255
+00:18:08,000 --> 00:18:11,720
+الشهر الخامس الانقسام الميتوزي إذا كان الجنين 
+
+256
+00:18:11,720 --> 00:18:18,580
+Female بتوقف، هذه النقطة الأولى طيب بالنسبة لـ ..
+
+257
+00:18:18,580 --> 00:18:22,830
+أنا خلصت بالنسبة لنقطة الأولى طبعا خلال هذين الشهرين 
+
+258
+00:18:22,830 --> 00:18:26,810
+إلى خمس شهور الـ Primordial Germ Cells بيزيد عددها
+
+259
+00:18:26,810 --> 00:18:30,470
+بشكل كبير جدا تصل إلى ملايين، تصل عند الـ Female
+
+260
+00:18:30,470 --> 00:18:35,230
+تقريبا سبعة ملايين خلية، هذه السبعة ملايين خلية هيتطور
+
+261
+00:18:35,230 --> 00:18:41,430
+ويعطوني سبعة ملايين Oocyte The number represents the
+
+262
+00:18:41,430 --> 00:18:45,190
+maximum number of Germ Cells that are ever found
+
+263
+00:18:45,190 --> 00:18:49,590
+in the ovary يعني هدول السبعة ملايين Germ Cells هيتطوروا
+
+264
+00:18:49,590 --> 00:18:53,830
+إلى سبعة ملايين Oocyte وهي بتمثل عدد البويضات في الـ
+
+265
+00:18:53,830 --> 00:18:58,230
+Ovary طبعا لما أقول Ovaries كل سيدة في عندها مبيض 
+
+266
+00:18:58,230 --> 00:19:02,030
+على اليمين ومبيض على اليسار، محصلة البويضات الموجودة
+
+267
+00:19:02,030 --> 00:19:07,190
+في كل المبيضين سبعة ملايين بويضة أو سبعة ملايين 
+
+268
+00:19:07,450 --> 00:19:11,370
+Primordial Germ Cells طبعا ما بيبقوا 7 ملايين وما
+
+269
+00:19:11,370 --> 00:19:15,310
+بيستمروا 7 ملايين لإنه بيدخلوا في مراحل الـ Apoptosis
+
+270
+00:19:15,310 --> 00:19:20,990
+فيما بعد طبعا خلال هذه الفترة الـ Oogonia بتدخل في
+
+271
+00:19:20,990 --> 00:19:26,590
+مرحلة بنسميها Natural Degeneration أو التدمير
+
+272
+00:19:26,590 --> 00:19:30,630
+الطبيعي إنه كل خلية إلى Half-Life معين بعد كده لم 
+
+273
+00:19:30,630 --> 00:19:35,470
+تستعمل بتصير لها تدمير بنسميها هذه العملية الـ Atresia
+
+274
+00:19:35,660 --> 00:19:40,080
+إذا الـ Atresia هي عبارة عن تدمير طبيعي للـ Oogonia
+
+275
+00:19:40,080 --> 00:19:44,880
+تدمير طبيعي للـ Oogonia .. للـ Oogonia بينما الـ
+
+276
+00:19:44,880 --> 00:19:48,480
+Atresia في مرحلة ثانية بتشبه الـ Menstrual Cycle
+
+277
+00:19:48,480 --> 00:19:52,380
+أو الدورة الخاصة بالسيدة لأنه مافيش مقحت للبويضة
+
+278
+00:19:52,380 --> 00:19:57,520
+فتنزل مع بطانة الرحم في حالة البلد، أما الـ Oogonia
+
+279
+00:19:57,520 --> 00:20:01,980
+تدخل مرحلة Apoptosis أو الـ Degeneration طبيعية
+
+280
+00:20:01,980 --> 00:20:05,360
+بنسمي هذا الـ Degeneration الطبيعي Atresia طبعا 
+
+281
+00:20:05,360 --> 00:20:13,160
+الـAtresia تستمر خلال فترة حياة الأنثى من و هي جنين
+
+282
+00:20:13,160 --> 00:20:18,260
+حتى تصل مرحلة الـ monobiosis هي Atresia بشكل مستمر
+
+283
+00:20:18,260 --> 00:20:24,200
+و بشكل شهري و إلا كيف السيدة هتتخلص من الـ 7 مليون
+
+284
+00:20:24,200 --> 00:20:30,520
+بويضة أو 7 مليون جرسل هذه
+
+285
+00:20:30,520 --> 00:20:34,240
+الصورة بتبين لي الـ Atresia اللي بتصير من لحظة
+
+286
+00:20:35,710 --> 00:20:40,190
+الإخصاب مرورا بلحظة الميلاد يعني الفترة الجانبية
+
+287
+00:20:40,190 --> 00:20:45,510
+مرورا بلحظة الميلاد وصولا إلى مرحلة الـ monobios
+
+288
+00:20:45,510 --> 00:20:49,850
+طبعا في عندنا اللون الـ yellow أو الذهبي نسميها
+
+289
+00:20:49,850 --> 00:20:54,010
+follicular pool اللون الأخضر الـ Atresia اللي بيصير
+
+290
+00:20:54,010 --> 00:20:57,190
+فيها degeneration اللون ال purple هي ال growing
+
+291
+00:20:57,190 --> 00:21:00,470
+follicle المرحلة اللي بيصير فيها تطور الخلايا و
+
+292
+00:21:00,470 --> 00:21:04,610
+اللون اللي باللون ال red أو الـ Kermidi هي عبارة عن
+
+293
+00:21:04,610 --> 00:21:06,850
+الـ ovulated follicle هي المرحلة اللي بيصل فيها
+
+294
+00:21:06,850 --> 00:21:11,230
+ovulation طبعا فيها دياجرام بيمثل ال years وبيمثل
+
+295
+00:21:11,230 --> 00:21:15,270
+ال number of germ cell خلال فترات الحياة في أول
+
+296
+00:21:15,270 --> 00:21:22,910
+فترات الحياة قبل سن الرشد أو 15 أو 16 سنة  كواتبار
+
+297
+00:21:22,910 --> 00:21:27,270
+السن بيصل فيها اندي كمية كبيرة جدا من ال follicle
+
+298
+00:21:27,270 --> 00:21:31,610
+folds لأن ال follicle أو ال germ cell بتكون زي ما
+
+299
+00:21:31,610 --> 00:21:36,610
+هي في حالة خمول وفي حالة .. زي حاجة بتسميها
+
+300
+00:21:36,610 --> 00:21:41,770
+arrested phase و بيصير في هذه المرحلة atresia بشكل
+
+301
+00:21:41,770 --> 00:21:46,890
+واضح جدا لما بعد سن الرشد أو مقصير adult من 20 ل
+
+302
+00:21:46,890 --> 00:21:52,030
+30 أو ل 35 بلاقي أنا في عندي atresia زادت بشكل
+
+303
+00:21:52,030 --> 00:21:56,710
+ملحوظ طبعا زيادة ال atresia معناه هيصير في عندي
+
+304
+00:21:56,710 --> 00:22:01,290
+نقصان في ال follicular pool عشان كده اللون الدهبي
+
+305
+00:22:01,290 --> 00:22:06,560
+بلاقيه بيقل في المقابل، سيكون في عندي Follicle Growth
+
+306
+00:22:06,560 --> 00:22:10,800
+عشان الدورة أو الـ Menstrual Cycle وفي عندي
+
+307
+00:22:10,800 --> 00:22:14,680
+Ovulated Follicle بدأت تظهر طبعا هذا العمر من 20
+
+308
+00:22:14,680 --> 00:22:22,780
+أو من 15 حتى 35 من 40 فما فوق، بلاقي كل المرحلة
+
+309
+00:22:22,780 --> 00:22:29,880
+هذه كلها Atresia كمية قليلة جدا جدا جدا هي عبارة
+
+310
+00:22:29,880 --> 00:22:33,900
+عن Ovulated Follicle لأن في هذه المرحلة، مرحلة الـ
+
+311
+00:22:33,900 --> 00:22:37,940
+post-monobiose أو الـ monobiosal مافي عندي
+
+312
+00:22:37,940 --> 00:22:41,720
+bleeding بيصير، مافي عندي menstrual cycle بيصير
+
+313
+00:22:41,720 --> 00:22:46,180
+إلا بكمية قليلة جدا في السيدات، بنسبة قليلة جدا
+
+314
+00:22:46,180 --> 00:22:50,420
+بعد الـ 40 أو بعد الـ 45 طب ليش ما بيصير في عندي
+
+315
+00:22:50,420 --> 00:22:54,180
+ovulated follicle أو ما بيصير عندي menstrual
+
+316
+00:22:54,180 --> 00:22:57,960
+cycle؟ لأن كل الـ follicle الموجودة أو ال germ
+
+317
+00:22:57,960 --> 00:23:02,350
+cell الموجودة أو القوائدات الموجودة تم استهلاكها و
+
+318
+00:23:02,350 --> 00:23:08,050
+جزء كبير منها دخل في مرحلة الـ Atresia فبلاجي مخزن
+
+319
+00:23:08,050 --> 00:23:13,610
+البويضات الـ ovary تكون محصلة المخزون فيه تكاد
+
+320
+00:23:13,610 --> 00:23:18,270
+تكون منعدمة فما تصير عنده menstrual cycle بالإضافة
+
+321
+00:23:18,270 --> 00:23:21,790
+إلى إن الهرمونات تصير في عنده fluctuation في مستوى
+
+322
+00:23:21,790 --> 00:23:25,950
+الهرمونات أو في كفاءة الـ Receptor إذا الـ Atresia
+
+323
+00:23:25,950 --> 00:23:31,590
+بتكون واضحة قبل عملية البلوغ تزداد بشكل ملحوظ جدا
+
+324
+00:23:31,590 --> 00:23:35,710
+بعد البلوغ في مرحلة الضغط تكون هي المسيطرة على
+
+325
+00:23:35,710 --> 00:23:40,670
+حياة السيدة بعد ال post-menopausal stage فبتصير هي
+
+326
+00:23:40,670 --> 00:23:45,470
+اللي بتاخد أكبر حيز من الأحداث، lethargy انقسام
+
+327
+00:23:45,470 --> 00:23:49,950
+الميتوزي عند الذكور كمان أنا حكيت عند الإناث بتبقى
+
+328
+00:23:49,950 --> 00:23:54,010
+في الشهر الثاني للشهر الخامس من عمر الجنين للأنثى
+
+329
+00:23:54,010 --> 00:23:58,610
+عند الذكور يختلف، فألاقي أن انقسام الميتوزي عند
+
+330
+00:23:58,610 --> 00:24:03,510
+الذكور يبدأ بشكل مبكر جدا من مرحلة الـ Empyrionic
+
+331
+00:24:03,510 --> 00:24:08,210
+Testes ولكن يتوجه في الـ Second Trimester يعني
+
+332
+00:24:08,210 --> 00:24:11,950
+بداية ال Second Trimester يتوجه في بداية ال Second
+
+333
+00:24:11,950 --> 00:24:15,330
+Trimester لأنهم عارفين الحمل يقص تسعة شهور يقسم
+
+334
+00:24:15,330 --> 00:24:20,170
+First, Second, Third Trimester ثلاثة شهور الأولى،
+
+335
+00:24:20,170 --> 00:24:23,730
+ثلاثة شهور الثانية، ثلاثة شهور الأخيرة من واحد لثلاثة،
+
+336
+00:24:23,730 --> 00:24:28,330
+من أربعة لستة ومن سبعة لثمانية وتسعة لل Third
+
+337
+00:24:28,330 --> 00:24:34,170
+Trimester أو بتسميه ال third أو ال trimester طبعا
+
+338
+00:24:34,170 --> 00:24:37,510
+ال third trimester في ال second trimester يعني
+
+339
+00:24:37,510 --> 00:24:41,110
+بمعنى آخر في نهاية الشهر الثالث من الحمل إذا كان
+
+340
+00:24:41,110 --> 00:24:45,770
+الجنين ذكر يتوقف الانقسام الميتوزي و يظل انقسام
+
+341
+00:24:45,770 --> 00:24:54,050
+الميتوزي متوقفا and does not resume until حتى ال
+
+342
+00:24:54,050 --> 00:24:57,970
+puberty يعني بمعنى آخر إن الإنقسام الميتوزي يتوقف عند
+
+343
+00:24:57,970 --> 00:25:04,350
+الجنين الذكر من بداية الـ second trimester حتى سن
+
+344
+00:25:04,350 --> 00:25:07,190
+البلوغ بمجرد ما يصل الذكر لسن البلوغ يبدأ
+
+345
+00:25:07,190 --> 00:25:11,410
+الإنقسام الميتوزي يشتغل ويستمر مرة أخرى in
+
+346
+00:25:11,410 --> 00:25:14,070
+contrast to female germ cell male germ cell
+
+347
+00:25:14,070 --> 00:25:16,410
+maintains the ability to divide throughout
+
+348
+00:25:16,410 --> 00:25:21,270
+postnatal life بمعنى آخر إن ال germ cell الخاصة
+
+349
+00:25:21,270 --> 00:25:27,120
+بالذكر تستمر في الإنقسام طيلة فترة حياته، طيلة فترة
+
+350
+00:25:27,120 --> 00:25:30,280
+حياته، عشان كده بلاقي ال male بعد الخمسين و بعد
+
+351
+00:25:30,280 --> 00:25:33,720
+الستين و بعد السبعين، فيه عندهم spermatocyte و
+
+352
+00:25:33,720 --> 00:25:36,660
+spermateid، فيه عندهم spermatozoa و فيه عندهم
+
+353
+00:25:36,660 --> 00:25:40,680
+sperm، هذه كلها مصطلحات لل sperm، بينما ال female
+
+354
+00:25:40,680 --> 00:25:44,060
+ما بلاقي عندها oocyte بعد الخمسة و أربعين، نادر جدا
+
+355
+00:25:45,290 --> 00:25:48,030
+طبعا في منطقة في الـ testes endymal بنتسميها الـ
+
+356
+00:25:48,030 --> 00:25:52,670
+semi-nervostipule هي المنطقة المصنع المصنع اللي
+
+357
+00:25:52,670 --> 00:25:56,670
+بتتم فيها تصنيع ال sperm metocyte اللي بنتسميه
+
+358
+00:25:56,670 --> 00:26:00,890
+spermatogonia sperm metocyte أو ال sperm لما يكون
+
+359
+00:26:00,890 --> 00:26:05,190
+في منطقة ال seminal .. seminal .. semen .. nervous
+
+360
+00:26:05,190 --> 00:26:10,570
+tipule بسميه spermatogonia في بداية سن البلوغ الـ
+
+361
+00:26:10,570 --> 00:26:14,270
+spermatogonium بتمر بعدة مراحل من التغيرات من
+
+362
+00:26:14,270 --> 00:26:20,330
+القسم الميتوزي علشان تتحول من spermatogonium إلى
+
+363
+00:26:20,330 --> 00:26:25,690
+sperm .. إلى sperm وهذه العملية بتظل مستمرة طول
+
+364
+00:26:25,690 --> 00:26:32,290
+فترة حياة الذكر .. طول فترة حياة الذكر نجي للحدث
+
+365
+00:26:32,290 --> 00:26:36,130
+الثالث اللي بيصير وهو عبارة عن reduction in the
+
+366
+00:26:36,130 --> 00:26:39,940
+chromosome number طبعا عشان أقول reduction إذا لازم
+
+367
+00:26:39,940 --> 00:26:44,380
+يكون فيها انقسام منصف وانقسام المنصف هو عبارة عن
+
+368
+00:26:44,380 --> 00:26:50,120
+انقسام الميوزي وده انقسام ميوز عارفين ان خلية
+
+369
+00:26:50,120 --> 00:26:54,280
+بتكون فيها اثنين chromosome تعطيني خليتين كل واحدة
+
+370
+00:26:54,280 --> 0:26:57,580
+فيها واحد chromosome نسميها خلية فيها اثنين N
+
+371
+00:26:57,580 --> 00:27:01,440
+تعطيني two cell كل واحدة فيها one N عشان كده
+
+372
+00:27:01,440 --> 00:27:06,260
+بنسميه انقسام منصف او ميوز طبعا ال biological
+
+373
+00:27:06,260 --> 00:27:10,080
+significance of meiosis should be or will be
+
+374
+00:27:10,080 --> 00:27:13,220
+summarized as the following عشان أصبح عندي انقسام
+
+375
+00:27:13,220 --> 00:27:17,300
+ميوزي لازم أن ألخصه في أكثر من نقطة النقطة الأولى
+
+376
+00:27:17,300 --> 00:27:20,760
+نقطة ال reduction وإيش بيصير في ال reduction أنه
+
+377
+00:27:20,760 --> 00:27:26,040
+في عندي خلية تحتوي على diploid 2N أو 2S المقصود
+
+378
+00:27:26,040 --> 00:27:30,120
+بالـ2N هي الـ2 كروموزوم الـS اختصارا لكروموزوم
+
+379
+00:27:30,120 --> 00:27:35,120
+هتنقسم لتعطي خليتين و الخلية فيها 1N اللي بنسميه
+
+380
+00:27:35,280 --> 00:27:38,760
+Haploid So that the kind number of chromosome can
+
+381
+00:27:38,760 --> 00:27:42,380
+be maintained from generation to generation بهذه
+
+382
+00:27:42,380 --> 00:27:47,000
+الطريقة  قالية ال reduction التي تتبع انقسام
+
+383
+00:27:47,000 --> 00:27:52,280
+الميوزي بتم المحافظة على المادة الوراثية و
+
+384
+00:27:52,280 --> 00:27:55,720
+الكروموزومات لكي تنتقل من generation ل generation
+
+385
+00:27:55,720 --> 00:28:00,540
+لذلك هذه أول مرحلة من المراحل الميوزي يليها
+
+386
+00:28:00,540 --> 00:28:03,860
+independent أو حاجة نسميها
+
+387
+00:28:07,790 --> 00:28:11,630
+assortment أي بمعنى أخر إعادة التجميع إعادة
+
+388
+00:28:11,630 --> 00:28:15,090
+التجميع إيش بمعنى إعادة التجميع؟ إنه في عنده
+
+389
+00:28:15,090 --> 00:28:18,410
+جامطات من الذكر و هي المادة الوراثية اللي جاي من
+
+390
+00:28:18,410 --> 00:28:22,530
+ال sperm و جامطات من الأنثى و هي المادة الوراثية
+
+391
+00:28:22,530 --> 00:28:25,450
+اللي جاي من الأنثى كروموزومات ذكرية و كروموزومات
+
+392
+00:28:25,450 --> 00:28:30,270
+أنثوية لازم يجتمعوا مع بعض و يصير mix ما بينهم و
+
+393
+00:28:30,270 --> 00:28:34,890
+تبادل للمادة الوراثية هذا بنسميها التجميع الغير
+
+394
+00:28:34,890 --> 00:28:42,170
+مُعتمد يعني ما بيتمد على شيء بيدفعه بيصير بشكل مستقل
+
+395
+00:28:42,170 --> 00:28:45,670
+independent بعد كده بيصير حاجة بيسميها
+
+396
+00:28:45,670 --> 00:28:50,010
+redistribution
+
+397
+00:28:50,010 --> 00:28:54,550
+يعني إعادة التوزيع سبحان الله في مناطق على
+
+398
+00:28:54,550 --> 00:28:57,690
+الكروموزومات ال male و الكروموزومات ال female
+
+399
+00:28:57,690 --> 00:29:03,110
+متشابهة فبيصير تبديل المنطقة هذه بتروح كروموزوم
+
+400
+00:29:03,110 --> 00:29:06,080
+الأولى و المنطقة هي دي نفسها اللي موجودة على
+
+401
+00:29:06,080 --> 00:29:10,020
+كروموزوم الأنثى بتروح كروموزوم الذكر تحت مصطلح
+
+402
+00:29:10,020 --> 00:29:13,040
+redistribution redistribution for what?
+
+403
+00:29:13,400 --> 00:29:16,320
+redistribution for maternal and paternal genetic
+
+404
+00:29:16,320 --> 00:29:20,640
+information through this process called crossing
+
+405
+00:29:20,640 --> 00:29:25,280
+over اللي كنا ناس نسميها فيما سبق التصالب العبور
+
+406
+00:29:25,280 --> 00:29:29,460
+إيش التصالب العبور؟ ببساطة جدا أي كروموزوم في عنده
+
+407
+00:29:29,460 --> 00:29:33,380
+عبارة عن two sister chromatid two sister chromatid
+
+408
+00:29:33,860 --> 00:29:38,200
+لو الكروموزوم رقم واحد في الذكر بيجي في الكروموزوم
+
+409
+00:29:38,200 --> 00:29:42,140
+رقم واحد في الأنثى متقابلين ال sister chromatid
+
+410
+00:29:42,140 --> 00:29:46,000
+الداخلي في نقاط ومناطق معينة متشابهة على كيلو
+
+411
+00:29:46,000 --> 00:29:51,600
+الكروموزوم بتم تبادلهم تحت مصطلح redistribution أو
+
+412
+00:29:51,600 --> 00:29:56,620
+crossing over on a major compound of the first
+
+413
+00:29:56,620 --> 00:30:00,660
+meiotic division is genetic recombination takes a
+
+414
+00:30:00,660 --> 00:30:06,330
+change من المادة
+
+415
+00:30:06,330 --> 00:30:10,230
+الوراثية أو مناطق معينة موجودة على الكروموزوم بتتم
+
+416
+00:30:10,230 --> 00:30:16,170
+تبادلهم في السيستر كروماتيد الداخل One form of
+
+417
+00:30:16,170 --> 00:30:20,170
+recombination which typically occur early in the
+
+418
+00:30:20,170 --> 00:30:22,850
+prophase involve short segments and occur through
+
+419
+00:30:22,850 --> 00:30:27,660
+the mechanism similar to the homologous أحد صفات الـ
+
+420
+00:30:27,660 --> 00:30:32,060
+Redistribution أو الـ Recombination إن قطعة معينة 
+
+421
+00:30:32,060 --> 00:30:35,800
+موجودة على الـ Male أو الـ Female كروموزوم نفس
+
+422
+00:30:35,800 --> 00:30:38,220
+الكروموزوم طبعاً لما نقول كروموزوم 1 عند الـ Male 
+
+423
+00:30:38,220 --> 00:30:40,620
+و الـ Female أو كروموزوم 8 عند الـ Male و الـ
+
+424
+00:30:40,620 --> 00:30:45,520
+Female تصير تبادل لهذه القطعة بمصطلح يشبه إلى حد 
+
+425
+00:30:45,520 --> 00:30:49,820
+ما مصطلح التصاريف العجول وتشبه إلى حد ما حاجة
+
+426
+00:30:49,820 --> 00:30:53,500
+بنسميها الـ DNA repair شو يعني الـ DNA repair؟
+
+427
+00:30:53,500 --> 00:30:58,190
+يعني تصليح الأخطاء هل في أخطاء بتصير؟ هو يعتبر
+
+428
+00:30:58,190 --> 00:31:02,910
+انتقال القطعة من كروموزوم الأب إلى كروموزوم الأم
+
+429
+00:31:02,910 --> 00:31:06,350
+وانتقال نفس القطعة من كروموزوم الأم إلى كروموزوم 
+
+430
+00:31:06,350 --> 00:31:09,810
+الأب هي عبارة عن عملية قطع ولصق فهي عبارة عن 
+
+431
+00:31:09,810 --> 00:31:13,550
+repair وبعض الأحيان بيعمل check up عشان يتأكد إن
+
+432
+00:31:13,550 --> 00:31:17,270
+نفس القطعة نقلت أو لا طبعا هذه العملية عملية
+
+433
+00:31:17,270 --> 00:31:21,170
+crossing over أو redistribution بتصير في stage
+
+434
+00:31:21,170 --> 00:31:27,450
+معين بنسمي Pachytene stage  أيضاً هذه العملية لا تحدث
+
+435
+00:31:27,450 --> 00:31:31,810
+على الـ autosome للكروموزوم وهي الكروموزوم الجسدية
+
+436
+00:31:31,810 --> 00:31:36,330
+لها تحدث على 6 كروموزوم زي ال X و ال Y معقول هل في
+
+437
+00:31:36,330 --> 00:31:39,750
+مناطق على ال X تشبه المناطق الموجودة على ال Y؟
+
+438
+00:31:39,750 --> 00:31:43,550
+صحيح، في مناطق على ال X تتشبه مع المناطق الموجودة
+
+439
+00:31:43,550 --> 00:31:48,450
+على ال Y وهي عبارة عن مناطق حيوية ولكن لا تدخل في 
+
+440
+00:31:48,450 --> 00:31:51,810
+تحديد جنس المولود في هذه المناطق بيصير لها crossing
+
+441
+00:31:51,810 --> 00:31:56,790
+over أو redistribution أو استبدال crossing over is 
+
+442
+00:31:56,790 --> 00:32:01,550
+not okay و randomly طبعا هذه عملية التصالب والعبور 
+
+443
+00:32:01,550 --> 00:32:06,830
+أو عملية تبادل القطع ما بتصير بشكل عشوائي لا بتصير
+
+444
+00:32:06,830 --> 00:32:11,970
+تحت control بشكل عالي جدا بطريقة مرتبة جدا في
+
+445
+00:32:11,970 --> 00:32:15,390
+مناطق معينة جدا هذه المناطق في الغالب بيسموها hot
+
+446
+00:32:15,390 --> 00:32:19,010
+spot على الكروموزوم ما في حاجة بتصير داخل جسم
+
+447
+00:32:19,010 --> 00:32:24,870
+الإنسان بشكل عشوائي أو بشكل تلقائي في الوضع 
+
+448
+00:32:24,870 --> 00:32:32,110
+الطبيعي طبعا هذه صورة بتوضح لي الـ Prophase وهو 
+
+449
+00:32:32,110 --> 00:32:37,390
+عبارة عن انقسام أو طور من أطوار انقسام الميوزي لو
+
+450
+00:32:37,390 --> 00:32:41,290
+أنا جيت للطور التالت الـ Pachytene Stage اللي بيصير
+
+451
+00:32:41,290 --> 00:32:45,270
+فيه التصالب والعبور وعبارة عن أحد الأطوار اللي 
+
+452
+00:32:45,270 --> 00:32:48,860
+بيصير فيها ال crossing over يأتي مباشرة بعد تكوين 
+
+453
+00:32:48,860 --> 00:32:53,680
+الزيجوت طب شو هي الزيجوت؟ الزيجوت هي اندماج النواة
+
+454
+00:32:53,680 --> 00:32:57,900
+الخاصة بالـ Sperm مع النواة الخاصة بالـ Oocyte 
+
+455
+00:32:57,900 --> 00:33:03,620
+لتكوين نواة واحدة بنسميها زيجوت أو الزيجوت هي
+
+456
+00:33:03,620 --> 00:33:09,160
+عبارة عن خلية تحتوي على نواة واحدة هذه النواة تنتج
+
+457
+00:33:09,160 --> 00:33:12,660
+من اندماج المادة الوراثية الخاصة بالأب مع المادة
+
+458
+00:33:12,660 --> 00:33:17,760
+الوراثية الخاصة بالأم فبسميها زيجوت أسميها زي ما
+
+459
+00:33:17,760 --> 00:33:23,120
+ترونها طبعاً موقعها يعتمد على تنظيم البروتين التي
+
+460
+00:33:23,120 --> 00:33:28,600
+أُرغنزت الكروموزوم في الميوزيس فهذه العملية والمناطق 
+
+461
+00:33:28,600 --> 00:33:32,720
+اللي بيصير فيها الـ crossing over تعتمد على درجة
+
+462
+00:33:32,720 --> 00:33:38,080
+عالية من الكرتير والتأكد وتكتب بروتينات معينة 
+
+463
+00:33:38,080 --> 00:33:41,600
+مسؤولة عن عملية العملية من أشهر هذه العملية التي 
+
+464
+00:33:41,600 --> 00:33:46,880
+تعمل على إتمام عملية الـ crossing over بروتين نسميه 
+
+465
+00:33:46,880 --> 00:33:53,120
+Cohesin protein من أشهر البروتينات التي تساعد على 
+
+466
+00:33:53,120 --> 00:33:58,040
+إتمام وبدء الـ crossing over حيث تساعد على ربط 
+
+467
+00:33:58,040 --> 00:34:01,240
+الـ two sister chromatid مع بعض ومع البعض two 
+
+468
+00:34:01,240 --> 00:34:04,840
+sister chromatid عفوا المقصود في hold sister
+
+469
+00:34:04,840 --> 00:34:07,000
+chromatid together during division لما أقول two
+
+470
+00:34:07,000 --> 00:34:09,860
+sister chromatid يعني كل كروموزوم في two sister
+
+471
+00:34:09,860 --> 00:34:12,910
+chromatid لما أجيب كروموزوم واحد من الأب مع كروموزوم
+
+472
+00:34:12,910 --> 00:34:18,710
+واحد من الـ Oocyte لازم يصطفوا أمام بعض بشكل متوازي 
+
+473
+00:34:18,710 --> 00:34:22,010
+وبعدين ييجي الـ sister الكروماتيد الداخلي الخاص
+
+474
+00:34:22,010 --> 00:34:24,730
+بالأب مع ال sister الكروماتيد الداخلي الخاص بالأم 
+
+475
+00:34:24,730 --> 00:34:28,330
+بيصير فيهم crossing over طبعا البروتين اللي بيقوم 
+
+476
+00:34:28,330 --> 00:34:33,550
+بعملية الاصطفاف البروتين بنسميه Cohesin protein في
+
+477
+00:34:33,550 --> 00:34:36,710
+عملية ثانية بنسميها Hypermethylation هذه الـ 
+
+478
+00:34:36,710 --> 00:34:39,990
+Hypermethylation بتصير على ال DNA وبتصير على الـ 
+
+479
+00:34:39,990 --> 00:34:43,070
+هيستون والهيستون هو عبارة عن البروتين لكن الـ
+
+480
+00:34:43,070 --> 00:34:45,070
+Hypermethylation بتصير على الـ Histone ولما أقول
+
+481
+00:34:45,070 --> 00:34:48,010
+Hypermethylation يعني زيادة في عملية الـ 
+
+482
+00:34:48,010 --> 00:34:50,790
+Methylation شو هي الـ Methylation؟ الـ Methylation
+
+483
+00:34:50,790 --> 00:34:54,810
+هي عبارة عن عملية يتم فيها إضافة مجموعة Methyl 
+
+484
+00:34:54,810 --> 00:34:59,910
+group CH3 على الـ Cytosine طب على كل الـ Cytosine؟
+
+485
+00:34:59,910 --> 00:35:03,550
+لا على الـ Cytosine التي تتبعها جوانين فقط لغاية
+
+486
+00:35:03,550 --> 00:35:07,250
+طبعا لما نصير Hypermethylation على الـ Histone in
+
+487
+00:35:07,250 --> 00:35:10,650
+Chromatin بعمل indication specific site where DNA 
+
+488
+00:35:10,650 --> 00:35:14,650
+strand should be break and are later repaired
+
+489
+00:35:14,650 --> 00:35:16,910
+after crossing over لما يصير في عندي
+
+490
+00:35:16,910 --> 00:35:20,070
+Hypermethylation بيصير Relaxation للـ Histone
+
+491
+00:35:20,070 --> 00:35:24,150
+Relaxation للـ Histone بيسمح لبعض الإنزيمات تدخل وتقطع 
+
+492
+00:35:24,150 --> 00:35:27,430
+مناطق معينة هذه المناطق لازم يصير فيها 
+
+493
+00:35:27,430 --> 00:35:31,630
+crossing over بعد كده بيصير لها repairing في
+
+494
+00:35:31,630 --> 00:35:35,150
+بروتين آخر بيساعد في عملية ال crossing over بنسميه 
+
+495
+00:35:35,290 --> 00:35:39,350
+Condensin Protein أو Condensed Protein هذا مهم 
+
+496
+00:35:39,350 --> 00:35:44,850
+جدا للبروتين لأنه يعمل عملية مهمة جدا في عمل
+
+497
+00:35:44,850 --> 00:35:49,450
+Condensation للكروموزوم ناخذ ملاحظة مهمة جدا أن
+
+498
+00:35:49,450 --> 00:35:53,270
+الكروموزوم في الأصل المادة الوراثية الموجودة بداخله 
+
+499
+00:35:53,270 --> 00:35:57,190
+وهي الكروماتين لازم تكون Closed عشان تكون Closed
+
+500
+00:35:57,190 --> 00:36:01,170
+لازم تصير Condensed لأنها لما تصير Condensed هذا
+
+501
+00:36:01,170 --> 00:36:06,000
+يمنعها من أي ضرر ممكن يواجهها أي إنزيم ممكن يشتغل 
+
+502
+00:36:06,000 --> 00:36:09,820
+عليها طب علشان يصير ال crossing over لازم يصير في
+
+503
+00:36:09,820 --> 00:36:12,760
+عندي Decondensation لهذا الكروماتين، يعني 
+
+504
+00:36:12,760 --> 00:36:16,180
+Relaxation واللي بيعمل ال Relaxation هي عبارة عن 
+
+505
+00:36:16,180 --> 00:36:19,380
+الـ Hypermethylation لذلك، البروتين الـ Condensed 
+
+506
+00:36:19,380 --> 00:36:22,800
+يلعب دور مهم جدا في ال crossing over من
+
+507
+00:36:22,800 --> 00:36:26,740
+الكروموزوم اللي محتاجه لكلا الميوتك والميتوتك 
+
+508
+00:36:26,740 --> 00:36:32,040
+للاكمال بدون البروتين الـ Condensed ما فيه ميتوتك 
+
+509
+00:36:32,040 --> 00:36:36,060
+Division وما فيه ميوتك Division الـ Second Meiotic
+
+510
+00:36:36,060 --> 00:36:43,160
+Division أو انقسام الميوز الثاني هو انقسام منصف
+
+511
+00:36:43,160 --> 00:36:46,980
+وفي الغالب ... في الغالب انقسام الميوز الثاني هو
+
+512
+00:36:46,980 --> 00:36:53,040
+عبارة عن انقسام ميتوزي ولكن لا يسبقه طور تمهيدي 
+
+513
+00:36:53,040 --> 00:36:58,470
+يؤدي إلى زيادة عدد الكروموزومات لأن أي انقسام مثل 
+
+514
+00:36:58,470 --> 00:37:04,130
+انقسام الميتوزي يمر بالـ Prophase الـ Metaphase 
+
+515
+00:37:04,130 --> 00:37:08,770
+الـ Anaphase الـ Telophase هو يسبقه انقسام تمهيدي 
+
+516
+00:37:08,770 --> 00:37:13,790
+انقسام تمهيدي أو عفوا طور تمهيدي بتمثيل تضاعف 
+
+517
+00:37:13,790 --> 00:37:18,010
+المادة الوراثية تضاعف المادة الوراثية فبالتالي
+
+518
+00:37:18,010 --> 00:37:22,950
+انقسام الميوزي الثاني هو عبارة عن انقسام ميتوزي
+
+519
+00:37:22,950 --> 00:37:28,480
+ولكن لا يسبقه طور تمهيدي تضاعف المادة الوراثية
+
+520
+00:37:28,480 --> 00:37:32,060
+عشان كده بتدخل اتنين n وتطلع two cell كل واحدة 
+
+521
+00:37:32,060 --> 00:37:38,500
+منهم one n فسمّاه انقسام منصف صورة بتوضح لي 
+
+522
+00:37:38,500 --> 00:37:41,420
+الكلام اللي أنا حكيته على البويضة الصورة ممكن
+
+523
+00:37:41,420 --> 00:37:45,220
+تلاقيها معقدة ولكن خلينا ناخدها step by step تحت
+
+524
+00:37:45,220 --> 00:37:49,420
+عنوان the major event of human oogenesis and 
+
+525
+00:37:49,420 --> 00:37:53,900
+follicular development هي عمر السيدة عمر السيدة 
+
+526
+00:37:53,900 --> 00:38:00,380
+يقسم لكتاليفترة أو العمر الجنيني ما قبل الولادة حتى
+
+527
+00:38:00,380 --> 00:38:05,300
+الولادة نبدأ من اليسار بعد الولادة وبعد الولادة 
+
+528
+00:38:05,300 --> 00:38:09,400
+هذه ثلاث أحداث ايش بيصير فيها؟ طبعا لو انا طلعت 
+
+529
+00:38:09,400 --> 00:38:14,840
+على الصورة الصورة عبارة عن بويضة سمّوها بهذا الشكل في
+
+530
+00:38:14,840 --> 00:38:18,320
+ما قبل الميلاد أو عفوا الطور الجنيني اللي بتسميه
+
+531
+00:38:18,320 --> 00:38:23,040
+fetal period no follicles مافي follicles تكونت
+
+532
+00:38:24,060 --> 00:38:29,840
+الـ Follicle هي عبارة عن بويضات موجودة داخل خلية 
+
+533
+00:38:29,840 --> 00:38:33,340
+محفظة، بسميها لكل الـ Structure Follicle وهذه ما 
+
+534
+00:38:33,340 --> 00:38:37,080
+بتكون إلا في وجود الرحم وعفوا، وجود المبيض، الذي
+
+535
+00:38:37,080 --> 00:38:39,500
+يعتبر جزء من الجهاز التناسلي الـ Reproductive 
+
+536
+00:38:39,500 --> 00:38:43,440
+System طبعا الـ Fetal Period لسه ما فيه Ovary تكون
+
+537
+00:38:43,440 --> 00:38:46,260
+لأن الـ Primordial Germ Cell لسه خارج منطقة
+
+538
+00:38:46,260 --> 00:38:52,640
+الكونية فما فيه No Follicle قبل الميلاد تكون الـ
+
+539
+00:38:52,640 --> 00:38:55,500
+Follicle بدأت تتكون والـ Primordial Germ Cell اللي
+
+540
+00:38:55,500 --> 00:39:00,560
+تكونت بعد الميلاد بسمي ال Primordial Germ Cell أو
+
+541
+00:39:00,560 --> 00:39:03,900
+الـ Primordial Follicle إلى Primary Follicle بعد 
+
+542
+00:39:03,900 --> 00:39:07,060
+البلوغ بسمي ال Primary Follicle Secondary Follicle
+
+543
+00:39:07,060 --> 00:39:11,580
+بعدين بسميها Tertiary بعدين بصير Ovulated Oocyte
+
+544
+00:39:11,580 --> 00:39:15,120
+بعدين ال Fertilization Oocyte انصار Fertilization 
+
+545
+00:39:15,120 --> 00:39:19,740
+طب ايش الأحداث اللي بتصير؟ في ناس بيسميها أو علماء 
+
+546
+00:39:19,740 --> 00:39:24,080
+بيسموها أو مدارس بيسموها تسمية أخرى في منطقة الـ
+
+547
+00:39:24,080 --> 00:39:28,160
+Fetal Primordial بيسموها Oogonium حكينا ايش هي الـ
+
+548
+00:39:28,160 --> 00:39:32,240
+Oogonium هي عبارة عن Primordial Germ Cell خضعت
+
+549
+00:39:32,240 --> 00:39:38,280
+لانقسام ميتوزي متكرر وصلت لسبعة ملايين بعد كده جاب
+
+550
+00:39:38,280 --> 00:39:44,080
+للميلاد حتى الميلاد بيسميها Primary Oocyte طبعا
+
+551
+00:39:44,080 --> 00:39:46,620
+الأحداث اللي بتصير ما بين ال Oogonium و ال Primary 
+
+552
+00:39:46,620 --> 00:39:51,800
+Oocyte هي انقسامات ميتوزية علشان كده السيدة أو
+
+553
+00:39:51,800 --> 00:39:58,040
+الأنثى عندما تولد يكون المبيض يحتوي على خلايا تقدر 
+
+554
+00:39:58,040 --> 00:40:02,040
+بعدد كبير ملايين الخلايا هنعرف قد ايش العدد بالضبط
+
+555
+00:40:02,040 --> 00:40:09,060
+تسمى Primary Oocyte طالما هو عبارة عن جنين بسميها
+
+556
+00:40:09,060 --> 00:40:14,500
+Oogonium أول ما يصير مولود Baby حي بسميها Primary
+
+557
+00:40:14,500 --> 00:40:19,380
+Oocyte طبعا ال Primary Oocyte بتخضع لانقسام ميوزي 
+
+558
+00:40:20,300 --> 00:40:24,400
+وتظلها حتى بعد الميلاد على شكل الـ primary oocyte
+
+559
+00:40:24,400 --> 00:40:29,360
+بعد الميلاد بتصير عملية Arrested استقرار وإيقاف
+
+560
+00:40:29,360 --> 00:40:34,660
+للانقسام الميتوزي في طور معين وهو عبارة عن الـ
+
+561
+00:40:34,660 --> 00:40:41,180
+diplotene stage الخاص بالانقسام الميتوزي إذا وصلت
+
+562
+00:40:41,180 --> 00:40:46,400
+الأنثى إلى سن البلوغ 8، 9، 10، 11، 12، 13 whatever
+
+563
+00:40:47,310 --> 00:40:55,390
+الـ Primary Oocyte تبقى Primary Oocyte وتستكمل
+
+564
+00:40:55,390 --> 00:40:59,050
+انقسام الميوزي الأول لأنه صار في عندي إيقاف
+
+565
+00:40:59,050 --> 00:41:03,490
+لانقسام الميوزي الأول في مرحلة نُسميها الـ
+
+566
+00:41:03,490 --> 00:41:08,470
+diplotene stage تستكمل انقسام الميوزي الأول بمجرد
+
+567
+00:41:08,470 --> 00:41:13,650
+استكمالها انقسام الميوزي الأول  حطيحصلني خلية تسمى
+
+568
+00:41:13,650 --> 00:41:20,490
+secondary oocyte وخلية تسمى polar body أيش الفرق
+
+569
+00:41:20,490 --> 00:41:23,010
+بين ال secondary oocyte و ال polar body تعالى
+
+570
+00:41:23,010 --> 00:41:26,950
+ناخدها من الأول ال Oogonia بيقول فيها عندها خلية
+
+571
+00:41:26,950 --> 00:41:32,270
+تحتوي على two chromosome two C نين S two S يعني
+
+572
+00:41:32,270 --> 00:41:36,370
+two chromosome الـ Primary Oocyte لأنها اتخضعت 
+
+573
+00:41:36,370 --> 00:41:40,210
+لانقسام ميتوزي يحدث فيه تضاعف لعدد الكروموزومات
+
+574
+00:41:40,210 --> 00:41:45,070
+وتضاعف الخلايا فاعطاني Primary Oocyte تحتوي على 4S
+
+575
+00:41:45,070 --> 00:41:50,450
+يعني أربع كروموزومات تستمر على شكل Primary Oocyte
+
+576
+00:41:50,450 --> 00:41:54,030
+Primary Oocyte ومجرد ال Primary Oocyte بعد ما
+
+577
+00:41:54,030 --> 00:41:57,370
+اتوقفت في الـ Diplotene Stage الخاص بالانقسام
+
+578
+00:41:57,370 --> 00:42:01,610
+الميتوزي الأول معناه هي ما كملت انقسام الميتوزي
+
+579
+00:42:01,610 --> 00:42:06,380
+الأول بمجرد ما تكمل انقسام الـ mitosis الأول و هو
+
+580
+00:42:06,380 --> 00:42:11,720
+الذي يحدث بمجرد وصول السيدة إلى سن الرشد الخلايا
+
+581
+00:42:11,720 --> 00:42:16,800
+اللي بتكون 4C تتحول إلى خليتين، كل خلية فيها اثنين
+
+582
+00:42:16,800 --> 00:42:21,080
+أس، الاثنين أس التانية، وين راحت؟ تحولت إلى polar
+
+583
+00:42:21,080 --> 00:42:24,960
+body يعني في عندي خلية هي عبارة عن ال primary
+
+584
+00:42:24,960 --> 00:42:28,490
+oocyte كملت الإنقسام اللي تحتوي على الاربعة
+
+585
+00:42:28,490 --> 00:42:33,750
+كروموزومات، كملت الإنقسام الميتوزي الأول فعطتني خلية
+
+586
+00:42:33,750 --> 00:42:38,290
+فيها 2S وخلية فيها 2S، الخلية الأولى فيها 2S سميتها
+
+587
+00:42:38,290 --> 00:42:42,290
+secondary oocyte و الخلية التانية فيها 2S سميتها
+
+588
+00:42:42,290 --> 00:42:47,110
+polar body why؟ ليش أنا سميتها polar body؟ لأنها
+
+589
+00:42:47,110 --> 00:42:51,030
+عبارة عن خلية تحتوي على 2 كروموزومات، 2 من
+
+590
+00:42:51,030 --> 00:42:55,290
+الكروموزومات، ولكن كمية الهضيات وكمية الـ cytoplasm
+
+591
+00:42:55,290 --> 00:43:00,110
+اللي موجودة فيها لا تكفي أو لا تكفيها لكي ترتقي
+
+592
+00:43:00,110 --> 00:43:04,350
+إلى أن تصبح بويضة ناضجة فبسميها polar body هل تخضع
+
+593
+00:43:04,350 --> 00:43:06,890
+لل fertilization؟ ليس لها علاقة بال fertilization
+
+594
+00:43:06,890 --> 00:43:11,610
+هل تنقسم؟ بعض المدارس بيقولك تنقسم ولكن لا ترتقي
+
+595
+00:43:11,610 --> 00:43:15,450
+إلى درجة secondary oocyte لكي تكمل عملية النقسام
+
+596
+00:43:15,450 --> 00:43:20,650
+ونحصل على بويضة ناضجة الـ secondary oocyte بعد
+
+597
+00:43:20,650 --> 00:43:25,470
+البلوغ بيصير اللي هي عملية ovulation على شكل
+
+598
+00:43:25,470 --> 00:43:28,890
+secondary oocyte طب السؤال ال secondary oocyte
+
+599
+00:43:28,890 --> 00:43:32,530
+فيها اثنين كروموزوم و لو لقحت هتاخد كمان كروموزوم
+
+600
+00:43:32,530 --> 00:43:35,690
+من الذكر، الـ sperm هيصير فيه عندي ثلاثة كروموزوم
+
+601
+00:43:35,690 --> 00:43:39,950
+يعني عدد الكروموزومات لازم تكون في الطبيعة اثنين
+
+602
+00:43:39,950 --> 00:43:43,150
+فإذا حصلت على ثلاثة فلا تصلح لعملية ال
+
+603
+00:43:43,150 --> 00:43:48,580
+fertilization البويضة إذا صارها ovulation على شكل
+
+604
+00:43:48,580 --> 00:43:56,720
+secondary oocyte وتحتوي على 2 كروموزوم تكون صالحة
+
+605
+00:43:56,720 --> 00:44:01,400
+لل fertilization ولا تستكمل عملية الانقسام الميوزي
+
+606
+00:44:01,400 --> 00:44:05,800
+التالي إلا بعد عملية ال fertilization بمجرد ما
+
+607
+00:44:05,800 --> 00:44:09,660
+يصير fertilization وهذا اللي بنسميها secondary
+
+608
+00:44:09,660 --> 00:44:13,660
+oocyte plus polar body بتصيرها arrested في مرحلة
+
+609
+00:44:13,660 --> 00:44:17,760
+ال metaphase 2 إيه شعر مرحلة ال metaphase 2؟ يعني الـ
+
+610
+00:44:17,760 --> 00:44:21,200
+metaphase الخاص بالانقسام الميوزي الثاني فهل في
+
+611
+00:44:21,200 --> 00:44:24,260
+انقسام ميوزي ثاني؟ أكيد لأن احنا حكينا انقسام
+
+612
+00:44:24,260 --> 00:44:27,340
+الميوزي هو عبارة عن ميوزي أول وميوزي ثاني الميوزي
+
+613
+00:44:27,340 --> 00:44:30,440
+الثاني يشبه انقسام الميتوزي ولكن لا يسبقه تضاعف
+
+614
+00:44:30,440 --> 00:44:33,520
+المادة الوراثية فيه بمجرد ما يصير fertilization
+
+615
+00:44:33,520 --> 00:44:38,180
+ودخول ال sperm ال sperm بعمل activation للبويضة
+
+616
+00:44:38,180 --> 00:44:43,120
+اللي في شكل secondary oocyte علشان تكمل انقسام
+
+617
+00:44:43,120 --> 00:44:47,080
+الميوزي تكمل انقسام الميوزي كيف؟ هتفصل الـ two
+
+618
+00:44:47,080 --> 00:44:51,660
+chromosome واحد هيطلع بخلية تسمى secondary polar
+
+619
+00:44:51,660 --> 00:44:56,520
+body والتاني هيبقى داخل ال oocyte عشان يندمج مع ال
+
+620
+00:44:56,520 --> 00:44:59,980
+chromosome اللي جاي من ال sperm ويحصل لي على خلية
+
+621
+00:44:59,980 --> 00:45:05,700
+تحتوي على two chromosome بسميها fertilized oocyte
+
+622
+00:45:05,700 --> 00:45:11,620
+يعني المحصلة النهائية هي عبارة عن mature oocyte
+
+623
+00:45:11,620 --> 00:45:18,510
+تحتوي plus one polar body أو fertilized oocyte plus
+
+624
+00:45:18,510 --> 00:45:24,050
+two polar body خليني أشوف الفيديو اللي بتكلم عن
+
+625
+00:45:24,050 --> 00:45:29,370
+هذه العملية طبعا
+
+626
+00:45:29,370 --> 00:45:33,650
+هذا الفيديو بتكلم كيف بتصير عملية ال fertilization
+
+627
+00:45:33,650 --> 00:45:41,150
+وعملية ال oogenesis طبعا هذا عندي هذه منطقة ال
+
+628
+00:45:41,150 --> 00:45:43,830
+cervical هذه منطقة الرحم هذه منطقة الفلوبيا
+
+629
+00:45:43,830 --> 00:45:48,420
+الكيوبا هذه منطقة ال ovary في منطقة الـ ovary في
+
+630
+00:45:48,420 --> 00:45:57,020
+عند الـ fully kill بتكون مصفوفة على طول ال ovary
+
+631
+00:45:57,020 --> 00:46:00,340
+طبعا هذه المراحل اللي بيمر فيها من اليمين لليسار
+
+632
+00:46:00,340 --> 00:46:05,420
+بتكون primordial
+
+633
+00:46:05,420 --> 00:46:11,400
+germ cell وخلافه أو immature oocyte أو first
+
+634
+00:46:11,400 --> 00:46:15,940
+oocyte أو primary oocyte مش المسمى ولكن أكثر
+
+635
+00:46:16,240 --> 00:46:20,200
+المسميات انتشارا هي ال primary oocyte أو ال
+
+636
+00:46:20,200 --> 00:46:24,060
+oogonia بعدين تديني primary لأن حكينا oogonia
+
+637
+00:46:24,060 --> 00:46:32,380
+primary secondary خلينا نشوف أيش العملية تصير فيها
+
+638
+00:46:32,380 --> 00:46:39,660
+هذا
+
+639
+00:46:39,660 --> 00:46:45,780
+بيعمل zoom على البويضة هي ال oogonia عمل zoom لها
+
+640
+00:46:46,680 --> 00:46:52,140
+البويضة بدأت تتطور دخلت الانقسام الميتوزي علشان
+
+641
+00:46:52,140 --> 00:47:00,060
+تتضاعف، تضاعفت البويضة اعطتلي اثنتين مثلا أو جونيام
+
+642
+00:47:00,060 --> 00:47:05,400
+هتدخل انقسام نمت هتدخل انقسام الميوزي الأول فيه
+
+643
+00:47:05,400 --> 00:47:10,840
+عنده two chromosome وعشانها بويضة لازم تاخد
+
+644
+00:47:10,840 --> 00:47:13,680
+كروموزوم من الأم وكروموزوم من الأب لذا هذا ال two
+
+645
+00:47:13,680 --> 00:47:17,040
+chromosome لازم تفصل نحصل على واحد كروموزوم والتاني
+
+646
+00:47:17,040 --> 00:47:21,980
+جيميل الأب طيب هتدخل انقسام ميوزي أول ومجرد إيه
+
+647
+00:47:21,980 --> 00:47:26,900
+primary oocyte primary oocyte دخلت انقسام ميوزي
+
+648
+00:47:26,900 --> 00:47:31,900
+أول هيتخلص من هذا الكروموزوم على شكل polar body
+
+649
+00:47:31,900 --> 00:47:37,580
+وعندي هذا الكروموزوم طبعا خد بالك كروموزوم هو عبارة
+
+650
+00:47:37,580 --> 00:47:41,140
+عن two sister chromatid فلازم تخلص من one sister
+
+651
+00:47:41,140 --> 00:47:45,070
+chromatid علشان ناخد الثاني من الأب فبالتالي بحصل
+
+652
+00:47:45,070 --> 00:47:49,450
+على زوج من الكروموزوم خلص منه أو chromatid
+
+653
+00:47:49,450 --> 00:47:52,590
+whatever المسمى مش عندهم كثير عن المسمى حاليا لأن
+
+654
+00:47:52,590 --> 00:47:56,670
+هموضحها قدام بالتحصيل إن شاء الله هداني polar body
+
+655
+00:47:56,670 --> 00:48:02,870
+و secondary oocyte دخلت في انقسام الميوزي الثاني
+
+656
+00:48:02,870 --> 00:48:07,410
+كملته طبعا هداني secondary polar body بس علشان
+
+657
+00:48:07,410 --> 00:48:12,650
+يكون الموضوع واضح جدا إن انقسام الميوزي الثاني لا
+
+658
+00:48:13,050 --> 00:48:17,730
+يحدث ولا يتم إلا بمجرد حدوث ال fertilization
+
+659
+00:48:17,730 --> 00:48:22,030
+طالما البويضة ما صارلها fertilization تبقى secondary
+
+660
+00:48:22,030 --> 00:48:27,410
+oocyte بدون second polar body لكن هذا animation ما
+
+661
+00:48:27,410 --> 00:48:33,110
+بقدر أوضحها فيه في ال animation هذا بالفعل طبعا
+
+662
+00:48:33,110 --> 00:48:36,630
+هنا بيقول الفولار بادي قد ينقسم صحيح قد ينقسم ولكن
+
+663
+00:48:36,630 --> 00:48:39,630
+لا يرتقي إلى بويضة تلقح عشان كده بيصير له
+
+664
+00:48:39,630 --> 00:48:44,110
+degradation عشان كده بيصير له degradation فيما بعد
+
+665
+00:48:44,110 --> 00:48:48,770
+هذه
+
+666
+00:48:48,770 --> 00:48:53,270
+الفولار بادي بيصير لها عملية تدمير و removing و
+
+667
+00:48:53,270 --> 00:48:57,890
+بعدين بيصير لها the ghost أنا سايرالايسز داخل الخلية
+
+668
+00:48:57,890 --> 00:49:03,990
+حصلت على employ egg طبعا جاهزة للتلقيح بس ده مش
+
+669
+00:49:03,990 --> 00:49:07,710
+دقيق، ال animation كثير هنشوف animation ثاني أكثر
+
+670
+00:49:07,710 --> 00:49:12,170
+دقة إن شاء الله هذا بالنسبة إلى تصنيع ال oocyte
+
+671
+00:49:12,170 --> 00:49:15,910
+ال primary و ال secondary ال first polar body و ال
+
+672
+00:49:15,910 --> 00:49:20,210
+second polar body كيف يتم عملية التنصيب هنكتفي
+
+673
+00:49:20,210 --> 00:49:24,610
+بذا القدر في هذه المحاضرة على أن نستكمل في
+
+674
+00:49:24,610 --> 00:49:28,870
+المحاضرة القادمة إن شاء الله توم توم في حفظ الله
+
+675
+00:49:28,870 --> 00:49:29,910
+وارعة
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Z4YwVN8UPs8_raw.json b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Z4YwVN8UPs8_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..df1428af5ac6e39587d5fe30e9f5161c65af46ad
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/Z4YwVN8UPs8_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 1682, "start": 1.53, "end": 16.83, "text": "بسم الله الرحمن الرحيم الصلاة والسلام على أشرف المرسلين سيدنا محمد الصادق الأمين أما بعد بداية أراحب بكم جميعا جديد وأرجو من الله الكريم أن تكونوا جميعا بخير و بصحة جيدة", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 31767, 15040, 3660, 16070, 3794, 37440, 15844, 5551, 8592, 28480, 9673, 2288, 3794, 1211, 9957, 8608, 25708, 8315, 3714, 35571, 3215, 31767, 18513, 4587, 16247, 2304, 9957, 5551, 15042, 39182, 4724, 28259, 10632, 5551, 23557, 5016, 3555, 4724, 24793, 10874, 2304, 40228, 995, 10874, 16254, 3215, 36725, 47341, 2407, 9154, 21984, 33251, 16572, 2304, 14739, 6055, 30544, 14407, 10874, 2304, 40228, 995, 4724, 9778, 13546, 4032, 4724, 9381, 5016, 3660, 10874, 25708, 3660], "avg_logprob": -0.10871611750987639, "compression_ratio": 1.811764705882353, "no_speech_prob": 6.556510925292969e-07, "words": [{"start": 1.53, "end": 1.89, "word": "بسم", "probability": 0.813232421875}, {"start": 1.89, "end": 2.21, "word": " الله", "probability": 0.96240234375}, {"start": 2.21, "end": 2.81, "word": " الرحمن", "probability": 0.9724934895833334}, {"start": 2.81, "end": 3.41, "word": " الرحيم", "probability": 0.9928385416666666}, {"start": 3.41, "end": 3.97, "word": " الصلاة", "probability": 0.7788899739583334}, {"start": 3.97, "end": 4.61, "word": " والسلام", "probability": 0.9298502604166666}, {"start": 4.61, "end": 4.93, "word": " على", "probability": 0.75048828125}, {"start": 4.93, "end": 5.43, "word": " أشرف", "probability": 0.9547526041666666}, {"start": 5.43, "end": 6.13, "word": " المرسلين", "probability": 0.9888671875}, {"start": 6.13, "end": 6.71, "word": " سيدنا", "probability": 0.93798828125}, {"start": 6.71, "end": 7.37, "word": " محمد", "probability": 0.98388671875}, {"start": 7.37, "end": 7.97, "word": " الصادق", "probability": 0.9871419270833334}, {"start": 7.97, "end": 8.57, "word": " الأمين", "probability": 0.9466145833333334}, {"start": 8.57, "end": 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اتراجيا بشكل مستمر و بشكل شهري و إلا كيف السيدة هتتخلص من الـ 7 مليون بوايضة أو 7 مليون جرسل هذه الصورة بتبين لي الاتراجيا اللي بتصير من لحظة", "tokens": [9566, 3555, 3615, 995, 2423, 9307, 2288, 26108, 25528, 6055, 14851, 29973, 16490, 1211, 6027, 6156, 2655, 25720, 11331, 25528, 3660, 16247, 1863, 12984, 7578, 9154, 4032, 39896, 10874, 1863, 9957, 11331, 49975, 6055, 36520, 3714, 2288, 5016, 37977, 2423, 39184, 1108, 996, 48783, 39896, 1975, 2655, 2288, 26108, 25528, 4724, 8592, 28820, 3714, 14851, 29973, 4032, 4724, 8592, 28820, 13412, 3224, 16572, 4032, 11933, 15040, 9122, 33911, 21136, 25708, 3660, 8032, 2655, 2655, 9778, 1211, 9381, 9154, 2423, 39184, 1614, 3714, 20292, 11536, 4724, 14407, 1829, 11242, 3660, 34051, 1614, 3714, 20292, 11536, 10874, 2288, 3794, 1211, 29538, 31767, 13063, 3660, 39894, 3555, 9957, 32239, 2423, 9307, 2288, 26108, 25528, 13672, 1829, 39894, 9381, 13546, 9154, 5296, 5016, 19913, 3660], "avg_logprob": -0.20350922607496136, "compression_ratio": 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"start": 1235.71, "end": 1261.89, "text": "الاخصاب مرورا بلحظة الميلاد يعني الفترة الجانبية مرورا بلحظة الميلاد وصولا إلى مرحلة الـ monobios طبعا في عند اللون الـ yellow أو الذهبي نسميها follicular pool اللون الأخضر الأتراجيا اللي بيصير فيها degeneration اللون ال purple هي ال growing follicle المرحلة اللي بيصير فيها تطور الخلايا و اللون اللي باللون ال red", "tokens": [6027, 47283, 9381, 16758, 3714, 2288, 13063, 995, 4724, 1211, 5016, 19913, 3660, 9673, 1829, 15040, 3215, 37495, 22653, 27188, 2655, 25720, 25724, 7649, 3555, 10632, 3714, 2288, 13063, 995, 4724, 1211, 5016, 19913, 3660, 9673, 1829, 15040, 3215, 4032, 9381, 12610, 995, 30731, 3714, 2288, 5016, 37977, 2423, 39184, 1108, 996, 2717, 23032, 3555, 3615, 995, 8978, 43242, 13672, 11536, 2423, 39184, 5566, 34051, 32545, 3224, 21292, 8717, 38251, 1829, 11296, 25483, 14646, 7005, 13672, 11536, 16247, 9778, 11242, 2288, 16247, 2655, 2288, 26108, 25528, 13672, 1829, 4724, 1829, 9381, 13546, 8978, 11296, 368, 30372, 13672, 11536, 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1430.51, "word": " الشهر", "probability": 0.986328125}, {"start": 1430.51, "end": 1430.99, "word": " التاني", "probability": 0.8645833333333334}, {"start": 1430.99, "end": 1431.83, "word": " للشهر", "probability": 0.92041015625}, {"start": 1431.83, "end": 1432.33, "word": " الخامس", "probability": 0.9889322916666666}, {"start": 1432.33, "end": 1432.51, "word": " من", "probability": 0.98876953125}, {"start": 1432.51, "end": 1432.75, "word": " عمر", "probability": 0.9453125}, {"start": 1432.75, "end": 1433.21, "word": " الجنين", "probability": 0.9728190104166666}, {"start": 1433.21, "end": 1434.01, "word": " للأنثى", "probability": 0.70849609375}, {"start": 1434.01, "end": 1434.69, "word": " عند", "probability": 0.869140625}, {"start": 1434.69, "end": 1435.07, "word": " الذكور", "probability": 0.9777018229166666}, {"start": 1435.07, "end": 1436.13, "word": " يختلف،", "probability": 0.7757568359375}, {"start": 1436.13, "end": 1436.59, "word": " فألاقي", "probability": 0.648284912109375}, {"start": 1436.59, "end": 1436.89, "word": " أن", "probability": 0.6376953125}, {"start": 1436.89, "end": 1437.75, "word": " انقسام", "probability": 0.9688720703125}, {"start": 1437.75, "end": 1438.37, "word": " الميتوزي", "probability": 0.967578125}, {"start": 1438.37, "end": 1438.61, "word": " عند", "probability": 0.9921875}, {"start": 1438.61, "end": 1439.23, "word": " الذكور", "probability": 0.9666341145833334}], "temperature": 1.0}, {"id": 53, "seek": 146889, "start": 1439.71, "end": 1468.89, "text": "ببدأ بشكل مبكر جدا من مرحلة الـ Empyrionic Testes ولكن بتوجه في الـ Second Trimester يعني بداية ال Second Trimester بتوجه في بداية ال Second Trimester لإنوا عارفين الحمل يقص تسعة شهور يقسم First, Second, Third Trimester تلت شهور الأولى، تلت شهور التانية، تلت شهور الأخيرة من واحد لدلده، من أربع على ستة ومن سبعة تمانية تسعة لل Third Trimester", "tokens": [3555, 44510, 10721, 4724, 8592, 28820, 3714, 3555, 37983, 10874, 28259, 9154, 3714, 2288, 5016, 37977, 2423, 39184, 8599, 6016, 313, 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should be or will be summarized as the following عشان أصبح عندي انقسام ميوزي لازم أن ألخصه في أكثر من نقطة النقطة الأولى نقطة ال reduction وإيش بيصير في ال reduction أنه في عندى خلية تحتوي على deploy 2N أو 2S المقصود بالـ2N هي الـ2 كروموزوم الـS اختصارا لكروموزوم هتنقسم لتعطي خليتك و الخلية فيها 1N اللي بنسميه", "tokens": [9566, 3555, 3615, 995, 2423, 13910, 17687, 295, 385, 48783, 820, 312, 420, 486, 312, 14611, 1602, 382, 264, 3480, 6225, 8592, 7649, 5551, 9381, 49628, 43242, 1829, 16472, 4587, 3794, 10943, 3714, 1829, 2407, 11622, 1829, 5296, 31377, 2304, 14739, 5551, 1211, 9778, 9381, 3224, 8978, 5551, 4117, 49115, 9154, 8717, 47432, 3660, 28239, 47432, 3660, 16247, 12610, 7578, 8717, 47432, 3660, 2423, 11004, 4032, 28814, 1829, 8592, 4724, 1829, 9381, 13546, 8978, 2423, 11004, 14739, 3224, 8978, 43242, 7578, 16490, 1211, 10632, 6055, 33753, 45865, 15844, 7274, 568, 45, 34051, 568, 50, 9673, 4587, 9381, 23328, 20666, 39184, 17, 45, 39896, 2423, 39184, 17, 9122, 2288, 20498, 2407, 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{"start": 2324.86, "end": 2325.12, "word": " Cell", "probability": 0.9140625}, {"start": 2325.12, "end": 2325.54, "word": " لسه", "probability": 0.98828125}, {"start": 2325.54, "end": 2325.86, "word": " خارج", "probability": 0.9939778645833334}, {"start": 2325.86, "end": 2326.26, "word": " منطقة", "probability": 0.9786783854166666}, {"start": 2326.26, "end": 2326.76, "word": " الكونية", "probability": 0.6398111979166666}, {"start": 2326.76, "end": 2327.7, "word": " فما", "probability": 0.93603515625}, {"start": 2327.7, "end": 2328.2, "word": " فيه", "probability": 0.90869140625}, {"start": 2328.2, "end": 2328.54, "word": " No", "probability": 0.8017578125}, {"start": 2328.54, "end": 2329.0, "word": " Follicle", "probability": 0.9716796875}, {"start": 2329.0, "end": 2330.08, "word": " جبل", "probability": 0.750732421875}, {"start": 2330.08, "end": 2330.98, "word": " الميلاد", "probability": 0.9619140625}, {"start": 2330.98, "end": 2332.44, "word": " تكون", "probability": 0.668701171875}, {"start": 2332.44, "end": 2332.64, "word": " الـ", "probability": 0.645263671875}, {"start": 2332.64, "end": 2332.92, "word": " Follicle", "probability": 0.9794921875}, {"start": 2332.92, "end": 2333.26, "word": " بدأت", "probability": 0.9112955729166666}, {"start": 2333.26, "end": 2333.68, "word": " تتكون", "probability": 0.9361979166666666}], "temperature": 1.0}, {"id": 85, "seek": 236271, "start": 2334.06, "end": 2362.72, "text": "و ال primordial germ cell اللي اتكونت بعد الميلاد بسمي ال primordial germ cell أو ال primordial follicle إلى primar follicle بعد البلو بسمي ال primar follicle secondary follicle بعدين بسميها tertiary بعدين بصير ovulated oocyte بعدين ال fertilization oocyte انصار fertilization طب إيش الأحداث اللي بتصير؟ في ناس بيسميها أو علماء بيسموها أو مدارس بيسموها تسمية أخرى", "tokens": [2407, 2423, 2886, 765, 831, 19858, 2815, 13672, 1829, 1975, 2655, 30544, 2655, 39182, 9673, 1829, 15040, 3215, 4724, 38251, 1829, 2423, 2886, 765, 831, 19858, 2815, 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"word": " primordial", "probability": 0.6444905598958334}, {"start": 2334.92, "end": 2335.12, "word": " germ", "probability": 0.88671875}, {"start": 2335.12, "end": 2335.38, "word": " cell", "probability": 0.87841796875}, {"start": 2335.38, "end": 2335.5, "word": " اللي", "probability": 0.557861328125}, {"start": 2335.5, "end": 2336.18, "word": " اتكونت", "probability": 0.7322998046875}, {"start": 2336.18, "end": 2337.84, "word": " بعد", "probability": 0.7939453125}, {"start": 2337.84, "end": 2338.4, "word": " الميلاد", "probability": 0.968017578125}, {"start": 2338.4, "end": 2338.84, "word": " بسمي", "probability": 0.8245442708333334}, {"start": 2338.84, "end": 2338.9, "word": " ال", "probability": 0.79931640625}, {"start": 2338.9, "end": 2339.5, "word": " primordial", "probability": 0.9417317708333334}, {"start": 2339.5, "end": 2339.76, "word": " germ", "probability": 0.9130859375}, {"start": 2339.76, "end": 2340.2, "word": " cell", "probability": 0.958984375}, {"start": 2340.2, "end": 2340.56, "word": " أو", "probability": 0.55517578125}, {"start": 2340.56, "end": 2340.74, "word": " ال", "probability": 0.8486328125}, {"start": 2340.74, "end": 2341.28, "word": " primordial", "probability": 0.9222005208333334}, {"start": 2341.28, "end": 2341.68, "word": " follicle", "probability": 0.886962890625}, {"start": 2341.68, "end": 2341.9, "word": " إلى", "probability": 0.3759765625}, {"start": 2341.9, "end": 2342.38, "word": " primar", "probability": 0.4228515625}, {"start": 2342.38, "end": 2342.86, "word": " follicle", "probability": 0.898681640625}, {"start": 2342.86, "end": 2343.9, "word": " بعد", "probability": 0.80712890625}, {"start": 2343.9, "end": 2344.72, "word": " البلو", "probability": 0.7801106770833334}, {"start": 2344.72, "end": 2345.2, "word": " بسمي", "probability": 0.9842122395833334}, {"start": 2345.2, "end": 2345.26, "word": " ال", "probability": 0.88671875}, {"start": 2345.26, "end": 2345.68, "word": " primar", "probability": 0.841064453125}, {"start": 2345.68, "end": 2346.04, "word": " follicle", "probability": 0.95263671875}, {"start": 2346.04, "end": 2346.46, "word": " secondary", "probability": 0.162353515625}, {"start": 2346.46, "end": 2347.06, "word": " follicle", "probability": 0.947998046875}, {"start": 2347.06, "end": 2347.72, "word": " بعدين", "probability": 0.7142333984375}, {"start": 2347.72, "end": 2348.16, "word": " بسميها", "probability": 0.970458984375}, {"start": 2348.16, "end": 2348.7, "word": " tertiary", "probability": 0.95361328125}, {"start": 2348.7, "end": 2349.44, "word": " بعدين", "probability": 0.90478515625}, {"start": 2349.44, "end": 2349.74, "word": " بصير", "probability": 0.8818359375}, {"start": 2349.74, "end": 2350.5, "word": " ovulated", "probability": 0.760498046875}, {"start": 2350.5, "end": 2351.58, "word": " oocyte", "probability": 0.86328125}, {"start": 2351.58, "end": 2352.16, "word": " بعدين", "probability": 0.84716796875}, {"start": 2352.16, "end": 2352.26, "word": " ال", "probability": 0.80908203125}, {"start": 2352.26, "end": 2352.96, "word": " fertilization", "probability": 0.89794921875}, {"start": 2352.96, "end": 2353.48, "word": " oocyte", "probability": 0.9191080729166666}, {"start": 2353.48, "end": 2354.16, "word": " انصار", "probability": 0.6138916015625}, {"start": 2354.16, "end": 2355.12, "word": " fertilization", "probability": 0.862060546875}, {"start": 2355.12, "end": 2355.9, "word": " طب", "probability": 0.782958984375}, {"start": 2355.9, "end": 2356.02, "word": " إيش", "probability": 0.7093505859375}, {"start": 2356.02, "end": 2356.62, "word": " الأحداث", "probability": 0.9688720703125}, {"start": 2356.62, "end": 2356.8, "word": " اللي", "probability": 0.936279296875}, {"start": 2356.8, "end": 2357.84, "word": " بتصير؟", "probability": 0.93603515625}, {"start": 2357.84, "end": 2358.0, "word": " في", "probability": 0.6748046875}, {"start": 2358.0, "end": 2358.22, "word": " ناس", "probability": 0.965576171875}, {"start": 2358.22, "end": 2358.8, "word": " بيسميها", "probability": 0.928125}, {"start": 2358.8, "end": 2359.1, "word": " أو", "probability": 0.77001953125}, {"start": 2359.1, "end": 2359.74, "word": " علماء", "probability": 0.9298502604166666}, {"start": 2359.74, "end": 2360.32, "word": " بيسموها", "probability": 0.9865234375}, {"start": 2360.32, "end": 2360.54, "word": " أو", "probability": 0.71240234375}, {"start": 2360.54, "end": 2360.88, "word": " مدارس", "probability": 0.939453125}, {"start": 2360.88, "end": 2361.46, "word": " بيسموها", "probability": 0.9923828125}, {"start": 2361.46, "end": 2362.36, "word": " تسمية", "probability": 0.9641927083333334}, {"start": 2362.36, "end": 2362.72, "word": " أخرى", "probability": 0.9757486979166666}], "temperature": 1.0}, {"id": 86, "seek": 239250, "start": 2363.22, "end": 2392.5, "text": "في منطقة الـ Fetal Primordial بيسموها Ogonium حكينا إيش هي الـ Ogonium هي عبارة عن Primordial جنب سلخ خضعت لانقسام ميتوزي متكرر وصلت لسبعة ملوى بعد كده جاب للميلاد حتى الميلاد بيسميها Primary Oocyte طبعا الأحداث اللي بتصير ما بين ال Ogonium و ال Primary Oocyte هي انقسامات ميتوزية علشان كده السيدة أو الأنثى", "tokens": [41185, 9154, 9566, 28671, 2423, 39184, 479, 302, 304, 19671, 765, 831, 4724, 1829, 38251, 2407, 11296, 422, 10660, 2197, 11331, 4117, 1829, 8315, 11933, 1829, 8592, 39896, 2423, 39184, 422, 10660, 2197, 39896, 6225, 3555, 9640, 3660, 18871, 19671, 765, 831, 10874, 1863, 3555, 8608, 1211, 9778, 16490, 11242, 34268, 5296, 7649, 4587, 3794, 10943, 3714, 36081, 2407, 11622, 1829, 44650, 37983, 2288, 4032, 36520, 2655, 5296, 35457, 27884, 3714, 1211, 2407, 7578, 39182, 9122, 3215, 3224, 10874, 16758, 5296, 19528, 1829, 15040, 3215, 11331, 49975, 9673, 1829, 15040, 3215, 4724, 1829, 38251, 1829, 11296, 42576, 422, 31078, 975, 23032, 3555, 3615, 995, 16247, 24401, 5718, 104, 13672, 1829, 39894, 9381, 13546, 19446, 49374, 2423, 422, 10660, 2197, 4032, 2423, 42576, 422, 31078, 975, 39896, 16472, 4587, 3794, 10943, 9307, 3714, 36081, 2407, 11622, 10632, 11203, 8592, 7649, 9122, 3215, 3224, 21136, 25708, 3660, 34051, 16247, 1863, 12984, 7578], "avg_logprob": -0.17187500631572394, "compression_ratio": 1.7717391304347827, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 2363.22, "end": 2363.42, "word": "في", "probability": 0.87353515625}, {"start": 2363.42, "end": 2363.8, "word": " منطقة", "probability": 0.98779296875}, {"start": 2363.8, "end": 2364.08, "word": " الـ", "probability": 0.876953125}, {"start": 2364.08, "end": 2364.46, "word": " Fetal", "probability": 0.6626790364583334}, {"start": 2364.46, "end": 2365.48, "word": " Primordial", "probability": 0.8326822916666666}, {"start": 2365.48, "end": 2366.02, "word": " بيسموها", "probability": 0.90341796875}, {"start": 2366.02, "end": 2366.82, "word": " Ogonium", "probability": 0.7781575520833334}, {"start": 2366.82, "end": 2367.66, "word": " حكينا", "probability": 0.96728515625}, {"start": 2367.66, "end": 2367.86, "word": " إيش", "probability": 0.85107421875}, {"start": 2367.86, "end": 2368.02, "word": " هي", "probability": 0.89599609375}, {"start": 2368.02, "end": 2368.16, "word": " الـ", "probability": 0.65869140625}, {"start": 2368.16, "end": 2368.66, "word": " Ogonium", "probability": 0.9397786458333334}, {"start": 2368.66, "end": 2370.14, "word": " هي", "probability": 0.1614990234375}, {"start": 2370.14, "end": 2370.42, "word": " عبارة", "probability": 0.990966796875}, {"start": 2370.42, "end": 2370.58, "word": " عن", "probability": 0.99169921875}, {"start": 2370.58, "end": 2371.14, "word": " Primordial", "probability": 0.8636067708333334}, {"start": 2371.14, "end": 2371.42, "word": " جنب", "probability": 0.6024576822916666}, {"start": 2371.42, "end": 2371.76, "word": " سلخ", "probability": 0.8186848958333334}, {"start": 2371.76, "end": 2372.24, "word": " خضعت", "probability": 0.90771484375}, {"start": 2372.24, "end": 2372.78, "word": " لانقسام", "probability": 0.806591796875}, {"start": 2372.78, "end": 2373.26, "word": " ميتوزي", "probability": 0.84443359375}, {"start": 2373.26, "end": 2373.84, "word": " متكرر", "probability": 0.96533203125}, {"start": 2373.84, "end": 2374.56, "word": " وصلت", "probability": 0.9222005208333334}, {"start": 2374.56, "end": 2374.92, "word": " لسبعة", "probability": 0.7109375}, {"start": 2374.92, "end": 2375.94, "word": " ملوى", "probability": 0.7117919921875}, {"start": 2375.94, "end": 2377.12, "word": " بعد", "probability": 0.46240234375}, {"start": 2377.12, "end": 2377.6, "word": " كده", "probability": 0.9759114583333334}, {"start": 2377.6, "end": 2378.28, "word": " جاب", "probability": 0.939208984375}, {"start": 2378.28, "end": 2380.16, "word": " للميلاد", "probability": 0.75927734375}, {"start": 2380.16, "end": 2380.52, "word": " حتى", "probability": 0.6793212890625}, {"start": 2380.52, "end": 2380.94, "word": " الميلاد", "probability": 0.9464111328125}, {"start": 2380.94, "end": 2381.38, "word": " بيسميها", "probability": 0.95947265625}, {"start": 2381.38, "end": 2382.1, "word": " Primary", "probability": 0.81884765625}, {"start": 2382.1, "end": 2383.14, "word": " Oocyte", "probability": 0.90185546875}, {"start": 2383.14, "end": 2384.08, "word": " طبعا", "probability": 0.9542236328125}, {"start": 2384.08, "end": 2384.46, "word": " الأحداث", "probability": 0.80462646484375}, {"start": 2384.46, "end": 2384.6, "word": " اللي", "probability": 0.94140625}, {"start": 2384.6, "end": 2384.92, "word": " بتصير", "probability": 0.8102213541666666}, {"start": 2384.92, "end": 2385.1, "word": " ما", "probability": 0.72607421875}, {"start": 2385.1, "end": 2385.24, "word": " بين", "probability": 0.9921875}, {"start": 2385.24, "end": 2385.4, "word": " ال", "probability": 0.9716796875}, {"start": 2385.4, "end": 2385.98, "word": " Ogonium", "probability": 0.76611328125}, {"start": 2385.98, "end": 2386.08, "word": " و", "probability": 0.94970703125}, {"start": 2386.08, "end": 2386.18, "word": " ال", "probability": 0.619140625}, {"start": 2386.18, "end": 2386.62, "word": " Primary", "probability": 0.85107421875}, {"start": 2386.62, "end": 2387.32, "word": " Oocyte", "probability": 0.9485677083333334}, {"start": 2387.32, "end": 2387.82, "word": " هي", "probability": 0.92919921875}, {"start": 2387.82, "end": 2388.54, "word": " انقسامات", "probability": 0.9859375}, {"start": 2388.54, "end": 2389.26, "word": " ميتوزية", "probability": 0.9734375}, {"start": 2389.26, "end": 2390.18, "word": " علشان", "probability": 0.9786783854166666}, {"start": 2390.18, "end": 2390.5, "word": " كده", "probability": 0.9900716145833334}, {"start": 2390.5, "end": 2391.5, "word": " السيدة", "probability": 0.9772135416666666}, {"start": 2391.5, "end": 2391.8, "word": " أو", "probability": 0.84912109375}, {"start": 2391.8, "end": 2392.5, "word": " الأنثى", "probability": 0.92431640625}], "temperature": 1.0}, {"id": 87, "seek": 241938, "start": 2392.76, "end": 2419.38, "text": "عندما تولد يكون المبيض يحتوي على خلايا تقدر بعدد كبير ملايين الخلايا هنعرف قداش العدد بالضبط تسمى Primary Oocyte طالما هو عبارة عن جنين بسميها Ogonium أول ما يصير مولود بابي حي بسميها Primary Oocyte طبعا ال Primary Oocyte بتخضع لانقسام ميوزي", "tokens": [3615, 41260, 15042, 6055, 12610, 3215, 7251, 30544, 9673, 21292, 11242, 7251, 33753, 45865, 15844, 16490, 15040, 25528, 6055, 28543, 2288, 4724, 22488, 3215, 9122, 3555, 13546, 3714, 15040, 1829, 9957, 33962, 15040, 25528, 8032, 1863, 3615, 28480, 12174, 3215, 33599, 18863, 3215, 3215, 20666, 11242, 3555, 9566, 6055, 38251, 7578, 42576, 422, 31078, 975, 23032, 6027, 15042, 31439, 6225, 3555, 9640, 3660, 18871, 10874, 1863, 9957, 4724, 38251, 1829, 11296, 422, 10660, 2197, 5551, 12610, 19446, 7251, 9381, 13546, 3714, 12610, 23328, 4724, 16758, 1829, 11331, 1829, 4724, 38251, 1829, 11296, 42576, 422, 31078, 975, 23032, 3555, 3615, 995, 2423, 42576, 422, 31078, 975, 39894, 9778, 11242, 3615, 5296, 7649, 4587, 3794, 10943, 3714, 1829, 2407, 11622, 1829], "avg_logprob": -0.14895833184321722, "compression_ratio": 1.7873303167420815, "no_speech_prob": 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0.99267578125}, {"start": 2408.1, "end": 2408.48, "word": " جنين", "probability": 0.766845703125}, {"start": 2408.48, "end": 2409.06, "word": " بسميها", "probability": 0.8968505859375}, {"start": 2409.06, "end": 2409.68, "word": " Ogonium", "probability": 0.7159830729166666}, {"start": 2409.68, "end": 2410.78, "word": " أول", "probability": 0.92041015625}, {"start": 2410.78, "end": 2411.42, "word": " ما", "probability": 0.8017578125}, {"start": 2411.42, "end": 2411.82, "word": " يصير", "probability": 0.861328125}, {"start": 2411.82, "end": 2412.44, "word": " مولود", "probability": 0.9840494791666666}, {"start": 2412.44, "end": 2412.82, "word": " بابي", "probability": 0.7452799479166666}, {"start": 2412.82, "end": 2413.14, "word": " حي", "probability": 0.841552734375}, {"start": 2413.14, "end": 2414.0, "word": " بسميها", "probability": 0.9749755859375}, {"start": 2414.0, "end": 2414.5, "word": " Primary", "probability": 0.88427734375}, {"start": 2414.5, "end": 2415.44, "word": " Oocyte", "probability": 0.96484375}, {"start": 2415.44, "end": 2416.02, "word": " طبعا", "probability": 0.9345703125}, {"start": 2416.02, "end": 2416.1, "word": " ال", "probability": 0.9736328125}, {"start": 2416.1, "end": 2416.48, "word": " Primary", "probability": 0.52978515625}, {"start": 2416.48, "end": 2417.22, "word": " Oocyte", "probability": 0.9513346354166666}, {"start": 2417.22, "end": 2418.26, "word": " بتخضع", "probability": 0.8839111328125}, {"start": 2418.26, "end": 2418.84, "word": " لانقسام", "probability": 0.82099609375}, {"start": 2418.84, "end": 2419.38, "word": " ميوزي", "probability": 0.94033203125}], "temperature": 1.0}, {"id": 88, "seek": 244640, "start": 2420.3, "end": 2446.4, "text": "وبتظلها حتى بعد الميلاد على شكل الـ primary oocyte بعد الميلاد بتصير عملية arrested استقرار وإيقاف للانقسام الميتوزي في طور معين وهو عبارة عن الـ diprotin stage الخاص بالانقسام الميتوزي إذا وصلت الأنثى إلى سن البلوغ 8، 9، 10، 11، 12، 13 whatever", "tokens": [37746, 2655, 19913, 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0.789306640625}, {"start": 2444.4, "end": 2444.8, "word": " 10،", "probability": 0.875732421875}, {"start": 2444.8, "end": 2445.28, "word": " 11،", "probability": 0.934814453125}, {"start": 2445.28, "end": 2445.7, "word": " 12،", "probability": 0.922119140625}, {"start": 2445.7, "end": 2446.02, "word": " 13", "probability": 0.9296875}, {"start": 2446.02, "end": 2446.4, "word": " whatever", "probability": 0.5478515625}], "temperature": 1.0}, {"id": 89, "seek": 247492, "start": 2447.31, "end": 2474.93, "text": "الـ Primary Oocyte تبقى Primary Oocyte وتستكمل انقسام الميوزي الأول لأنه صار في عندي إيقاف لانقسام الميوزي الأول في مرحلة بنتسميها الـ diprotin stage تستكمل انقسام الميوزي الأول بمجرد استكمالها انقسام الميوزي الأول حطيقيني خلية تسمى secondary oocyte", "tokens": [6027, 39184, 42576, 422, 31078, 975, 6055, 3555, 4587, 7578, 42576, 422, 31078, 975, 34683, 14851, 24793, 1211, 16472, 4587, 3794, 10943, 9673, 1829, 2407, 11622, 1829, 16247, 12610, 5296, 33456, 3224, 20328, 9640, 8978, 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"text": "وخلية تسمى polar body أيش الفرق بين ال secondary oocyte و ال polar body تعالى ناخدها من الأول ال Ogonia بيقول فيها عندها خلية تحتوى على two chromosome two C نين S two S يعني two chromosome", "tokens": [2407, 9778, 1211, 10632, 6055, 38251, 7578, 12367, 1772, 36632, 8592, 27188, 2288, 4587, 49374, 2423, 11396, 277, 31078, 975, 4032, 2423, 12367, 1772, 37279, 6027, 7578, 8717, 47283, 3215, 11296, 9154, 16247, 12610, 2423, 422, 10660, 654, 4724, 1829, 39648, 8978, 11296, 43242, 11296, 16490, 1211, 10632, 6055, 33753, 2407, 7578, 15844, 732, 42896, 732, 383, 8717, 9957, 318, 732, 318, 37495, 22653, 732, 42896], "avg_logprob": -0.30923508797118915, "compression_ratio": 1.52, "no_speech_prob": 9.5367431640625e-07, "words": [{"start": 2475.39, "end": 2476.05, "word": "وخلية", "probability": 0.891845703125}, {"start": 2476.05, "end": 2476.65, "word": " تسمى", "probability": 0.9586588541666666}, {"start": 2476.65, "end": 2477.03, "word": " polar", "probability": 0.56103515625}, {"start": 2477.03, "end": 2477.51, "word": " body", "probability": 0.814453125}, {"start": 2477.51, "end": 2480.07, "word": " أيش", "probability": 0.4827880859375}, {"start": 2480.07, "end": 2480.49, "word": " الفرق", "probability": 0.97021484375}, {"start": 2480.49, "end": 2480.75, "word": " بين", "probability": 0.88330078125}, {"start": 2480.75, "end": 2480.87, "word": " ال", "probability": 0.54638671875}, {"start": 2480.87, "end": 2481.41, "word": " secondary", "probability": 0.8427734375}, {"start": 2481.41, "end": 2482.09, "word": " oocyte", "probability": 0.7109781901041666}, {"start": 2482.09, "end": 2482.17, "word": " و", "probability": 0.77392578125}, {"start": 2482.17, "end": 2482.25, "word": " ال", "probability": 0.66357421875}, {"start": 2482.25, "end": 2482.47, "word": " polar", "probability": 0.77685546875}, {"start": 2482.47, "end": 2482.75, "word": " body", "probability": 0.88818359375}, {"start": 2482.75, "end": 2483.01, "word": " تعالى", "probability": 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لعدد الكرموزومات وتضاعف الخلايا فاعطاني Primary Oocyte تحتوي على 4S يعني أربع كرموزومات تستمر على شكل Primary Oocyte Primary Oocyte ومجرد ال Primary Oocyte بعد ما اتوجفت في الـ Diploting Stage الخاص بالانقسام الميتوزي الأول معناه هي ما كمل انقسام الميتوزي الأول", "tokens": [6027, 39184, 42576, 422, 31078, 975, 5296, 33456, 11296, 1975, 2655, 9778, 11242, 34268, 5296, 7649, 4587, 3794, 10943, 3714, 36081, 2407, 11622, 1829, 7251, 24401, 12984, 8978, 3224, 6055, 11242, 45761, 5172, 5296, 22488, 3215, 33251, 2288, 2304, 2407, 11622, 20498, 9307, 34683, 11242, 45761, 5172, 33962, 15040, 25528, 6156, 45761, 9566, 7649, 1829, 42576, 422, 31078, 975, 6055, 33753, 45865, 15844, 1017, 50, 37495, 22653, 5551, 25513, 3615, 9122, 2288, 2304, 2407, 11622, 20498, 9307, 6055, 14851, 29973, 15844, 13412, 28820, 42576, 422, 31078, 975, 42576, 422, 31078, 975, 4032, 2304, 7435, 2288, 3215, 2423, 42576, 422, 31078, 975, 39182, 19446, 1975, 2655, 29245, 5172, 2655, 8978, 2423, 39184, 33486, 75, 17001, 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" بالانقسام", "probability": 0.9716796875}, {"start": 2517.37, "end": 2518.33, "word": " الميتوزي", "probability": 0.966015625}, {"start": 2518.33, "end": 2519.29, "word": " الأول", "probability": 0.983642578125}, {"start": 2519.29, "end": 2520.09, "word": " معناه", "probability": 0.90185546875}, {"start": 2520.09, "end": 2520.27, "word": " هي", "probability": 0.442626953125}, {"start": 2520.27, "end": 2520.43, "word": " ما", "probability": 0.96826171875}, {"start": 2520.43, "end": 2520.71, "word": " كمل", "probability": 0.5223388671875}, {"start": 2520.71, "end": 2521.15, "word": " انقسام", "probability": 0.9595947265625}, {"start": 2521.15, "end": 2521.61, "word": " الميتوزي", "probability": 0.98271484375}, {"start": 2521.61, "end": 2521.89, "word": " الأول", "probability": 0.975830078125}], "temperature": 1.0}, {"id": 92, "seek": 254564, "start": 2522.2, "end": 2545.64, "text": "بمجرد ما تكمل انقسام الـ mitosis الأول و هو الذي يحدث بمجرد وصول السيدة إلى سن الرشد الخلايا اللي بتكون 4C تتحول إلى خليتين، كل خلية فيها اتنين أس الاتنين أس التانية وين راحت؟ تحولت إلى polar body يعني في عندي خلية هي عبارة عن ال primary oocyte", "tokens": [3555, 2304, 7435, 2288, 3215, 19446, 6055, 24793, 1211, 16472, 4587, 3794, 10943, 2423, 39184, 2194, 8211, 16247, 12610, 4032, 31439, 43527, 7251, 24401, 12984, 4724, 2304, 7435, 2288, 3215, 4032, 9381, 12610, 21136, 1829, 41891, 30731, 8608, 1863, 34892, 8592, 3215, 33962, 15040, 25528, 13672, 1829, 39894, 30544, 1017, 34, 6055, 2655, 5016, 12610, 30731, 16490, 20292, 2655, 9957, 12399, 28242, 16490, 1211, 10632, 8978, 11296, 1975, 2655, 1863, 9957, 5551, 3794, 2423, 9307, 1863, 9957, 5551, 3794, 16712, 7649, 10632, 4032, 9957, 12602, 39319, 2655, 22807, 6055, 5016, 12610, 2655, 30731, 12367, 1772, 37495, 22653, 8978, 18871, 16254, 16490, 1211, 10632, 39896, 6225, 3555, 9640, 3660, 18871, 2423, 6194, 277, 31078, 975], "avg_logprob": -0.21480977561162864, "compression_ratio": 1.7012448132780082, "no_speech_prob": 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oocyte", "probability": 0.8046875}], "temperature": 1.0}, {"id": 93, "seek": 256819, "start": 2545.91, "end": 2568.19, "text": "كملت الإنقسام اللي تحتوي على الاربعة كرموزومات قملت الإنقسام الميتوزي الأول فعطتني خلية فيها 2S وخلية فيها 2S الخلية الأولى فيها 2S سميتها secondary oocyte و الخلية التانية فيها 2S سميتها polar body why؟ ليش أنا سميتها polar body؟ لأنها عبارة عن خلية", "tokens": [24793, 1211, 2655, 33688, 1863, 4587, 3794, 10943, 13672, 1829, 6055, 33753, 45865, 15844, 2423, 9640, 3555, 27884, 9122, 2288, 2304, 2407, 11622, 20498, 9307, 12174, 42213, 2655, 33688, 1863, 4587, 3794, 10943, 9673, 36081, 2407, 11622, 1829, 16247, 12610, 6156, 3615, 9566, 2655, 22653, 16490, 1211, 10632, 8978, 11296, 568, 50, 4032, 9778, 1211, 10632, 8978, 11296, 568, 50, 33962, 1211, 10632, 16247, 12610, 7578, 8978, 11296, 568, 50, 8608, 2304, 36081, 11296, 11396, 277, 31078, 975, 4032, 33962, 1211, 10632, 16712, 7649, 10632, 8978, 11296, 568, 50, 8608, 2304, 36081, 11296, 12367, 1772, 983, 22807, 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كروموزوم من الذكر ال spirit هيصير فيه عند تلاتة كروموزوم يعني عدد الكروموزومات لازم تكون في الطبيعة اتنين فإذا حصلت على تلاتة فلا تصلح لعملية ال fertilization البويضة إذا صارها ovulation", "tokens": [6027, 39184, 11396, 277, 31078, 975, 39182, 29739, 1211, 2407, 17082, 4724, 1829, 9381, 13546, 13672, 1829, 39896, 6225, 42213, 10632, 14187, 2776, 15844, 13412, 28820, 11396, 277, 31078, 975, 23032, 3555, 21136, 33604, 6027, 2423, 11396, 277, 31078, 975, 8978, 11296, 1975, 2655, 1863, 9957, 9122, 2288, 20498, 2407, 11622, 20498, 4032, 45164, 5296, 4587, 33753, 8032, 2655, 47283, 3215, 9122, 2304, 7649, 9122, 2288, 20498, 2407, 11622, 20498, 9154, 32545, 37983, 2423, 3797, 8032, 1829, 9381, 13546, 8978, 3224, 43242, 6055, 1211, 9307, 3660, 9122, 2288, 20498, 2407, 11622, 20498, 37495, 22653, 6225, 3215, 3215, 33251, 2288, 20498, 2407, 11622, 20498, 9307, 5296, 31377, 2304, 6055, 30544, 8978, 41950, 21292, 27884, 1975, 2655, 1863, 9957, 6156, 28814, 15730, 11331, 36520, 2655, 15844, 6055, 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الطبيعة", "probability": 0.9051106770833334}, {"start": 2619.55, "end": 2619.95, "word": " اتنين", "probability": 0.976318359375}, {"start": 2619.95, "end": 2620.49, "word": " فإذا", "probability": 0.7335611979166666}, {"start": 2620.49, "end": 2620.91, "word": " حصلت", "probability": 0.9798177083333334}, {"start": 2620.91, "end": 2620.99, "word": " على", "probability": 0.75390625}, {"start": 2620.99, "end": 2621.55, "word": " تلاتة", "probability": 0.9830322265625}, {"start": 2621.55, "end": 2622.05, "word": " فلا", "probability": 0.855712890625}, {"start": 2622.05, "end": 2622.55, "word": " تصلح", "probability": 0.9287109375}, {"start": 2622.55, "end": 2622.99, "word": " لعملية", "probability": 0.9324951171875}, {"start": 2622.99, "end": 2623.15, "word": " ال", "probability": 0.9541015625}, {"start": 2623.15, "end": 2623.87, "word": " fertilization", "probability": 0.919677734375}, {"start": 2623.87, "end": 2625.35, "word": " البويضة", "probability": 0.623748779296875}, {"start": 2625.35, "end": 2625.71, "word": " إذا", "probability": 0.903076171875}, {"start": 2625.71, "end": 2626.07, "word": " صارها", "probability": 0.9661458333333334}, {"start": 2626.07, "end": 2626.75, "word": " ovulation", "probability": 0.953369140625}], "temperature": 1.0}, {"id": 96, "seek": 265692, "start": 2627.98, "end": 2656.92, "text": "على شكل secondary oocyte وتحتوى على 2 كروموزوم تكون صالحة لل fertilization ولا تستكمل عملية الانقسام الميوزي التالي إلا بعد عملية ال fertilization بمجرد ما يصير fertilization وهذا اللي بنسميها secondary oocyte plus polar body بتصيرها arrested في مرحلة الmetaphase 2 إيه شعر مرحلة الmetaphase 2؟", "tokens": [3615, 23942, 13412, 28820, 11396, 277, 31078, 975, 34683, 33753, 2407, 7578, 15844, 568, 9122, 2288, 20498, 2407, 11622, 20498, 6055, 30544, 20328, 6027, 5016, 3660, 24976, 18512, 2144, 49429, 6055, 14851, 24793, 1211, 6225, 42213, 10632, 2423, 7649, 4587, 3794, 10943, 9673, 1829, 2407, 11622, 1829, 16712, 6027, 1829, 11933, 15040, 39182, 6225, 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{"start": 2654.94, "end": 2655.52, "word": " إيه", "probability": 0.6905110677083334}, {"start": 2655.52, "end": 2655.66, "word": " شعر", "probability": 0.7900390625}, {"start": 2655.66, "end": 2655.98, "word": " مرحلة", "probability": 0.93701171875}, {"start": 2655.98, "end": 2656.54, "word": " الmetaphase", "probability": 0.71014404296875}, {"start": 2656.54, "end": 2656.92, "word": " 2؟", "probability": 0.87841796875}], "temperature": 1.0}, {"id": 97, "seek": 268586, "start": 2657.0, "end": 2685.86, "text": "يعني الـ metaphase الخاص للانقسام الميوزي التاني فهل في انقسام ميوزي تاني؟ أكيد لأن احنا حكينا انقسام الميوزي هو عبارة عن ميوزي أول وميوزي تاني الميوزي التاني يشبه انقسام الميتوزي ولكن لا يسبق وتضاعف المادة الوراق فيها بمجرد ما يصير fertilization ودخول ال sperm ال sperm بعمل activation للبويضة اللي في شكل secondary oocyte علشان تكمل انقسام الميوزي تكمل انقسام الميوزي كيف؟", "tokens": [40228, 22653, 2423, 39184, 30946, 651, 33962, 33546, 24976, 7649, 4587, 3794, 10943, 9673, 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ينقسم صحيح قد ينقسم ولكن لا يرتقي الى بوادة تلقح عشان كده بيصيرله degradation عشان كده بيصيرله degradation فيما بعد هذه الفولار بادي بيصيرها عملية تدمير و removing و بعدين بيصيرها the ghost انا سايرالايسز داخل الخلية حصلت على employ egg طبعا", "tokens": [9566, 3555, 3615, 995, 34105, 4724, 1829, 39648, 27188, 12610, 9640, 4724, 995, 16254, 12174, 3215, 7251, 1863, 4587, 38251, 20328, 5016, 1829, 5016, 12174, 3215, 7251, 1863, 4587, 38251, 35525, 19452, 20193, 7251, 43500, 38436, 2423, 7578, 4724, 14407, 41891, 6055, 1211, 4587, 5016, 6225, 8592, 7649, 9122, 3215, 3224, 4724, 1829, 9381, 13546, 43761, 40519, 6225, 8592, 7649, 9122, 3215, 3224, 4724, 1829, 9381, 13546, 43761, 40519, 8978, 15042, 39182, 29538, 27188, 12610, 9640, 4724, 995, 16254, 4724, 1829, 9381, 13546, 11296, 6225, 42213, 10632, 6055, 40448, 13546, 4032, 12720, 4032, 39182, 9957, 4724, 1829, 9381, 13546, 11296, 264, 8359, 1975, 8315, 8608, 995, 13546, 6027, 47302, 3794, 11622, 11778, 47283, 1211, 33962, 1211, 10632, 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"word": " على", "probability": 0.9013671875}, {"start": 2938.55, "end": 2939.15, "word": " employ", "probability": 0.2802734375}, {"start": 2939.15, "end": 2940.13, "word": " egg", "probability": 0.58837890625}, {"start": 2940.13, "end": 2941.73, "word": " طبعا", "probability": 0.9775390625}], "temperature": 1.0}, {"id": 107, "seek": 296991, "start": 2942.21, "end": 2969.91, "text": "جاهزة للتلقيح بس ده مش دقيق ال animation كتير هنشوف animation تاني أكثر درجة ان شاء الله هذا بالنسبة إلى تصنيع ال oocyte ال primary وال secondary ال first polar body وال second polar body كيف يتم عملية التنصيب هنكتفي بهذا القدر في هذه المحاضرة على أن نستكمل في المحاضرة القادمة ان شاء الله توم توم في حفظ الله وارعة", "tokens": [7435, 40294, 11622, 3660, 24976, 2655, 1211, 38436, 5016, 4724, 3794, 11778, 3224, 37893, 11778, 38436, 4587, 2423, 9603, 9122, 2655, 13546, 8032, 1863, 8592, 38688, 9603, 6055, 7649, 1829, 5551, 4117, 49115, 11778, 47341, 3660, 16472, 13412, 16606, 21984, 23758, 20666, 1863, 35457, 3660, 30731, 6055, 9381, 22653, 3615, 2423, 277, 31078, 975, 2423, 6194, 16070, 11396, 2423, 700, 12367, 1772, 16070, 1150, 12367, 1772, 9122, 33911, 7251, 39237, 6225, 42213, 10632, 16712, 1863, 9381, 1829, 3555, 8032, 1863, 4117, 2655, 41185, 39627, 15730, 25062, 3215, 2288, 8978, 29538, 9673, 5016, 46958, 25720, 15844, 14739, 8717, 14851, 24793, 1211, 8978, 9673, 5016, 46958, 25720, 25062, 18513, 46007, 16472, 13412, 16606, 21984, 6055, 20498, 6055, 20498, 8978, 11331, 5172, 19913, 21984, 4032, 9640, 27884], "avg_logprob": -0.27999999904632566, "compression_ratio": 1.8254545454545454, "no_speech_prob": 3.1113624572753906e-05, "words": [{"start": 2942.21, "end": 2942.85, "word": "جاهزة", "probability": 0.822509765625}, {"start": 2942.85, "end": 2943.45, "word": " للتلقيح", "probability": 0.703369140625}, {"start": 2943.45, "end": 2943.71, "word": " بس", "probability": 0.782470703125}, {"start": 2943.71, "end": 2943.85, "word": " ده", "probability": 0.6805419921875}, {"start": 2943.85, "end": 2943.99, "word": " مش", "probability": 0.98388671875}, {"start": 2943.99, "end": 2944.35, "word": " دقيق", "probability": 0.94921875}, {"start": 2944.35, "end": 2944.53, "word": " ال", "probability": 0.384033203125}, {"start": 2944.53, "end": 2944.99, "word": " animation", "probability": 0.94921875}, {"start": 2944.99, "end": 2945.37, "word": " كتير", "probability": 0.86474609375}, {"start": 2945.37, "end": 2945.91, "word": " هنشوف", "probability": 0.68145751953125}, {"start": 2945.91, "end": 2946.31, "word": " animation", "probability": 0.76220703125}, {"start": 2946.31, "end": 2947.11, "word": " تاني", "probability": 0.6944173177083334}, {"start": 2947.11, "end": 2947.71, "word": " أكثر", "probability": 0.75341796875}, {"start": 2947.71, "end": 2948.37, "word": " درجة", "probability": 0.6378580729166666}, {"start": 2948.37, "end": 2948.55, "word": " ان", "probability": 0.6201171875}, {"start": 2948.55, "end": 2948.75, "word": " شاء", "probability": 0.98193359375}, 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{"start": 2954.67, "end": 2954.93, "word": " first", "probability": 0.92333984375}, {"start": 2954.93, "end": 2955.19, "word": " polar", "probability": 0.8017578125}, {"start": 2955.19, "end": 2955.49, "word": " body", "probability": 0.89990234375}, {"start": 2955.49, "end": 2955.91, "word": " وال", "probability": 0.53076171875}, {"start": 2955.91, "end": 2956.15, "word": " second", "probability": 0.6162109375}, {"start": 2956.15, "end": 2956.45, "word": " polar", "probability": 0.9580078125}, {"start": 2956.45, "end": 2956.83, "word": " body", "probability": 0.88330078125}, {"start": 2956.83, "end": 2957.41, "word": " كيف", "probability": 0.866455078125}, {"start": 2957.41, "end": 2957.65, "word": " يتم", "probability": 0.76708984375}, {"start": 2957.65, "end": 2958.13, "word": " عملية", "probability": 0.9889322916666666}, {"start": 2958.13, "end": 2959.19, "word": " التنصيب", "probability": 0.77275390625}, {"start": 2959.19, "end": 2960.21, "word": " هنكتفي", "probability": 0.785546875}, {"start": 2960.21, "end": 2960.93, "word": " بهذا", "probability": 0.57061767578125}, {"start": 2960.93, "end": 2961.39, "word": " القدر", "probability": 0.9894205729166666}, {"start": 2961.39, "end": 2961.81, "word": " في", "probability": 0.93798828125}, {"start": 2961.81, "end": 2962.05, "word": " هذه", "probability": 0.8935546875}, {"start": 2962.05, "end": 2962.63, "word": " المحاضرة", "probability": 0.986083984375}, {"start": 2962.63, "end": 2963.23, "word": " على", "probability": 0.76416015625}, {"start": 2963.23, "end": 2963.45, "word": " أن", "probability": 0.416748046875}, {"start": 2963.45, "end": 2964.15, "word": " نستكمل", "probability": 0.86224365234375}, {"start": 2964.15, "end": 2964.61, "word": " في", "probability": 0.76416015625}, {"start": 2964.61, "end": 2965.23, "word": " المحاضرة", "probability": 0.9810791015625}, {"start": 2965.23, "end": 2965.99, "word": " القادمة", "probability": 0.9952799479166666}, {"start": 2965.99, "end": 2966.59, "word": " ان", "probability": 0.84326171875}, {"start": 2966.59, "end": 2966.93, "word": " شاء", "probability": 0.991455078125}, {"start": 2966.93, "end": 2967.05, "word": " الله", "probability": 0.9443359375}, {"start": 2967.05, "end": 2967.45, "word": " توم", "probability": 0.47088623046875}, {"start": 2967.45, "end": 2967.77, "word": " توم", "probability": 0.760009765625}, {"start": 2967.77, "end": 2968.27, "word": " في", "probability": 0.412353515625}, {"start": 2968.27, "end": 2968.57, "word": " حفظ", "probability": 0.9801432291666666}, {"start": 2968.57, "end": 2968.87, "word": " الله", "probability": 0.96630859375}, {"start": 2968.87, "end": 2969.91, "word": " وارعة", "probability": 0.6234537760416666}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 3026.7675625, "duration_after_vad": 2927.751249999988}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/diNdtthu9cM.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/diNdtthu9cM.srt
new file mode 100644
index 0000000000000000000000000000000000000000..08325f9ee7bdb539506352c06e08dbd2c53bc99a
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/diNdtthu9cM.srt
@@ -0,0 +1,1819 @@
+1
+00:00:01,350 --> 00:00:04,750
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:04,750 --> 00:00:09,470
+المرسلين سيدنا محمد الصادق الأمين أما بعد توقفنا
+
+3
+00:00:09,470 --> 00:00:13,510
+في المحاضرة السابقة عند ال ovulatory phase as one
+
+4
+00:00:13,510 --> 00:00:16,910
+of the menstrual cycle stage or phase وقلنا أن هذا
+
+5
+00:00:16,910 --> 00:00:22,410
+الطور يستهلك ما يقارب من 32 ساعة إلى 16 ساعة من
+
+6
+00:00:22,410 --> 00:00:26,690
+خلال أيام الدورة الشهرية الكاملة التي تتمثل في 28
+
+7
+00:00:26,690 --> 00:00:32,290
+يوماً. في هذا الطور يتمثل خروج البويضة من المبيض تحت
+
+8
+00:00:32,290 --> 00:00:36,570
+مصطلح يُسمى الـ ovulation أي الطبويد وهذا الطبويد
+
+9
+00:00:36,570 --> 00:00:39,790
+يحدث بفعل هرمون يُسمى الـ luteinizing hormone حيث
+
+10
+00:00:39,790 --> 00:00:44,370
+عندما تصل لـ Graafian follicle الحجم المطلوب الذي
+
+11
+00:00:44,370 --> 00:00:47,830
+يدل على وصوله إلى الـ maturation stage تبدأ بإفراز
+
+12
+00:00:47,830 --> 00:00:51,970
+كمية كبيرة جداً من هرمون الـ estrogen. هذا الـ
+
+13
+00:00:51,970 --> 00:00:55,610
+estrogen هرمون يحفظ الـ pituitary gland anterior
+
+14
+00:00:55,610 --> 00:01:00,460
+loop لإفراز luteinizing hormoneالذي يعمل على تفجير
+
+15
+00:01:00,460 --> 00:01:06,620
+الفوليكل وخروج البويضة. البويضة خرجت من الفوليكل
+
+16
+00:01:06,620 --> 00:01:09,340
+الذي سمّيتها Graafian follicle والـ Graafian
+
+17
+00:01:09,340 --> 00:01:13,620
+follicle في المبايض يتحول إلى الجسم الأصفر أو corpus
+
+18
+00:01:13,620 --> 00:01:18,800
+luteum الذي يلعب دوراً مهماً جداً في عملية استمرار أو
+
+19
+00:01:18,800 --> 00:01:22,700
+تغذية الجسم بالـ progesterone هرمون في بداية الحمل
+
+20
+00:01:22,700 --> 00:01:28,790
+وهو الذي يعمل على استقرار الحمل في أول أيامه. طبعاً
+
+21
+00:01:28,790 --> 00:01:34,130
+في نهاية الـ wave الخاصة بالـ LH تبدأ عملية
+
+22
+00:01:34,130 --> 00:01:41,370
+التبويض بالحدوث ما بين 10 إلى 12 ساعة، يعني بعد الـ
+
+23
+00:01:41,370 --> 00:01:45,350
+wave أو نهاية الـ LH wave بعشر ساعات ممكن يصير
+
+24
+00:01:45,350 --> 00:01:49,550
+التبويض أو 12 ساعة ممكن يصير التبويض، فبالتالي الـ
+
+25
+00:01:49,550 --> 00:01:52,930
+LH وظيفته فقط الـ ovulation، ما له علاقة بالـ
+
+26
+00:01:52,930 --> 00:01:57,230
+maturation الذي له دور مهم في عملية ال maturation
+
+27
+00:01:57,230 --> 00:02:03,770
+هو الـ FSH. هرمون الـ FSH هرمون طبعاً، الـ oocyte about
+
+28
+00:02:03,770 --> 00:02:09,530
+24 hours after this day the egg will be die or
+
+29
+00:02:09,530 --> 00:02:14,260
+dissolve if there is no fertilization، okay. طبعاً
+
+30
+00:02:14,260 --> 00:02:18,380
+فترة حياة البويضة بعد التبويض 24 ساعة فقط، لغير، يعني
+
+31
+00:02:18,380 --> 00:02:20,460
+يوم كامل، يعني خلال هذا اليوم لازم يصير
+
+32
+00:02:20,460 --> 00:02:24,440
+fertilization أو intercourses علشان يصير عنده
+
+33
+00:02:24,440 --> 00:02:28,420
+pregnancy، يصير عنده fetus مستقبلاً، إذا ما صار فيه
+
+34
+00:02:28,420 --> 00:02:31,360
+intercourses، يعني ما صار فيه fertilization،
+
+35
+00:02:31,360 --> 00:02:36,260
+البويضة بتموت وبتدوب وتخرج مع ال bleeding في
+
+36
+00:02:36,260 --> 00:02:40,860
+مرحلة الـ menstrual phase. Fertilization is more
+
+37
+00:02:40,860 --> 00:02:44,280
+likely when sperm are present in the reproductive
+
+38
+00:02:44,280 --> 00:02:48,460
+tract before the egg is released. أفضل حالات ال
+
+39
+00:02:48,460 --> 00:02:52,980
+fertilization تحدث والأكثر حدوثاً أن ال sperm يكون
+
+40
+00:02:52,980 --> 00:02:56,920
+موجوداً في ال fallopian tube قبل أيام الطبوية بيوم
+
+41
+00:02:56,920 --> 00:03:00,180
+أو بيومين لأن ال sperm يتميز بأن ال half-life
+
+42
+00:03:00,180 --> 00:03:03,430
+الخاصة به تصل إلى ثلاثة أيام، بينما ال half-life تبعت ال
+
+43
+00:03:03,430 --> 00:03:06,650
+oocyte يوم واحد، علشان أطمئن أنه يحصل فيه pregnancy
+
+44
+00:03:06,650 --> 00:03:10,970
+ويحصل fertilization لازم يكون ال sperm في انتظار
+
+45
+00:03:10,970 --> 00:03:14,010
+البويضة، يعني ال sperm يكون وصل في لُبّ الـ tube
+
+46
+00:03:14,010 --> 00:03:18,950
+قبل البويضة، ما يصير لها عملية ovulation، وهذه أكثر
+
+47
+00:03:18,950 --> 00:03:23,590
+حالات لـ pregnancy حدوثاً. طبعاً، the egg released does
+
+48
+00:03:23,590 --> 00:03:27,130
+not alternate between the two ovaries and appear
+
+49
+00:03:27,130 --> 00:03:31,350
+to be random. بمعنى آخر أن ال ovary الأيمن والـ ovary
+
+50
+00:03:31,350 --> 00:03:36,130
+الأيسر كلاهما يعمل بشكل مستقل، بمعنى آخر أن كلاهما
+
+51
+00:03:36,130 --> 00:03:40,510
+يستطيع إخراج بويضة في نفس الشهر، ما في حاجة اسمها أن
+
+52
+00:03:40,510 --> 00:03:45,670
+المبيضين يتناوبوا، في شهر مايو يشغل المبيض الأيمن
+
+53
+00:03:45,670 --> 00:03:49,710
+في شهر يونيو يشغل الأيسر، في شهر يوليو يرجع الأيمن، في
+
+54
+00:03:49,710 --> 00:03:54,790
+شهر أغسطس يرجع الأيسر، ما في تناوب في العمل، والدليل
+
+55
+00:03:54,790 --> 00:04:00,850
+أن في بعض الأحيان ممكن يصير في عندي twins أو triple
+
+56
+00:04:00,850 --> 00:04:04,970
+لأن المبيض أفرز بويضتين، وهذا المبيض أفرز بويضة
+
+57
+00:04:04,970 --> 00:04:08,010
+أو أُفرز بويضة من المبيض الأيمن وبويضة من المبيض
+
+58
+00:04:08,010 --> 00:04:13,050
+الأيسر. حالة أخرى تؤكد هذا الكلام، بمعنى آخر إن
+
+59
+00:04:13,050 --> 00:04:17,150
+السيدة لو خضعت إلى عملية جراحية استُئصل أحد
+
+60
+00:04:17,150 --> 00:04:21,490
+المبيضين، فالمبيض الآخر سوف يستمر كل شهر في إفراز
+
+61
+00:04:21,490 --> 00:04:27,890
+وانضاج بويضة، ما بنلاقي شهر اه وشهر لا، فالعملية
+
+62
+00:04:28,160 --> 00:04:32,660
+بتكون بشكل عشوائي، ما في نوع من أنواع الترتيب. الطور
+
+63
+00:04:32,660 --> 00:04:35,540
+الأخير من أطوار الدورة الشهرية اللي بنسميه الـ luteal
+
+64
+00:04:35,540 --> 00:04:39,120
+phase أو حاجة بنسميها الـ post-ovulatory phase
+
+65
+00:04:39,120 --> 00:04:45,720
+وبتأخذ من 15 إلى 28 من أيام الدورة، خلال الـ luteal
+
+66
+00:04:45,720 --> 00:04:48,760
+phase، واللي بيصير بعد الـ rupture of the follicle
+
+67
+00:04:48,760 --> 00:04:51,480
+which causes releasing of the oocyte and forms a
+
+68
+00:04:51,480 --> 00:04:54,160
+structure called the corpus luteum. يعني الفولكل
+
+69
+00:04:54,160 --> 00:04:58,630
+صار له rupture، طلعت الـ oocyte، بعد ما تطلع الـ oocyte
+
+70
+00:04:58,630 --> 00:05:03,690
+هذه الفوليكة بتتحول إلى corpus luteum الذي يقوم
+
+71
+00:05:03,690 --> 00:05:06,810
+بإفراز وإزالة البروجسترون. هذا الـ corpus luteum
+
+72
+00:05:06,810 --> 00:05:10,890
+مهم جداً في أول بداية الحمل بعد أن يحدث البروجسترون
+
+73
+00:05:10,890 --> 00:05:16,570
+أو في أول العملية أو في أول عملية الـ luteal phase
+
+74
+00:05:16,570 --> 00:05:20,130
+أول أطوار الـ luteal phase، لأنه بيعمل على إنتاج كمية
+
+75
+00:05:20,130 --> 00:05:24,430
+كبيرة جداً من البروجسترون على أمل أن يحصل في عندي
+
+76
+00:05:24,430 --> 00:05:29,140
+البروجسترون. البروجسترون هل له وظيفة معينة؟ أكيد
+
+77
+00:05:29,140 --> 00:05:33,980
+البروجسترون بيعمل على تحفيز المبيض على تهيئة
+
+78
+00:05:33,980 --> 00:05:38,000
+المبيض لعملية الـ implantation من خلال تدعيم الـ
+
+79
+00:05:38,000 --> 00:05:42,220
+endometrium regeneration، تدعيم بطانة الرحم، caused
+
+80
+00:05:42,220 --> 00:05:46,220
+endometrium to thicken، بيخلي بطانة الرحم أكثر سماكة،
+
+81
+00:05:46,220 --> 00:05:50,880
+إذا صارت أكثر سماكة، يعني إن عندها قابلية أكبر إنها
+
+82
+00:05:50,880 --> 00:05:55,260
+تستقبل الجنين وتعمل له implantation. وبتصير أكثر
+
+83
+00:05:55,260 --> 00:05:59,060
+سماكة من خلال زيادة المواد الغذائية وإضافة الدم
+
+84
+00:05:59,060 --> 00:06:04,100
+إلى هذه المنطقة. Caused the mucus in the cervix to
+
+85
+00:06:04,100 --> 00:06:08,160
+thicken so that the sperm or bacteria are less
+
+86
+00:06:08,160 --> 00:06:11,880
+likely to enter the uterus. بيخلّي المنطقة الـ
+
+87
+00:06:11,880 --> 00:06:16,160
+cervical... الميوكاس، المنطقة الـ cervical الكثافة
+
+88
+00:06:16,160 --> 00:06:19,800
+تبعتها عالية جداً، فبيصير الميوكاس more thick، هذا
+
+89
+00:06:19,800 --> 00:06:24,370
+بيمنع أي sperm أو أي نوع من أنواع البكتيريا يدخلوا
+
+90
+00:06:24,370 --> 00:06:28,930
+يتخطّوا منطقة الـ cervix ويصلوا للرحم فيعملوا التهابات
+
+91
+00:06:28,930 --> 00:06:32,730
+حادة جداً في منطقة الرحم، مما يؤدي إلى إجهاض الجنين.
+
+92
+00:06:32,730 --> 00:06:35,810
+فالبروجسترون بيمنع الكلام هذا. شغل ثانية
+
+93
+00:06:35,810 --> 00:06:39,230
+البروجسترون بيعمل causing body temperature to
+
+94
+00:06:39,230 --> 00:06:43,630
+increase slightly during the luteal phase and remain
+
+95
+00:06:43,630 --> 00:06:47,870
+elevated until menstrual cycle period. علشان يحفظ
+
+96
+00:06:47,870 --> 00:06:52,350
+هذه المنطقة، أن يصير فيه إنه تجديد. أضف إلى ذلك أنه
+
+97
+00:06:52,350 --> 00:06:56,400
+بيحفظ جهاز المناعة. إن والله في عندي شيء غريب هيحدث
+
+98
+00:06:56,400 --> 00:07:00,440
+في منطقة الـ abdominal فلازم جهاز المناعة يظل محافظاً
+
+99
+00:07:00,440 --> 00:07:06,100
+يحفظ جهاز المناعة من خلال ارتفاع درجة حرارة الجسم
+
+100
+00:07:06,100 --> 00:07:11,740
+بشكل تدريجي، معناه جهاز المناعة عنده معيار معين
+
+101
+00:07:11,740 --> 00:07:17,110
+ارتفاع درجة الحرارة، معناه إن في عندي حالة أو خطر أو
+
+102
+00:07:17,110 --> 00:07:21,330
+حالة من الاستعداد يجب أن يكون فيه من خلال الجهاز
+
+103
+00:07:21,330 --> 00:07:26,850
+المناعي لأي invasion ممكن يصير للجسم، if the women
+
+104
+00:07:26,850 --> 00:07:30,070
+become pregnant، إذا صار في عندي fertilization
+
+105
+00:07:30,070 --> 00:07:33,430
+وشاء الأقدار وشاء الله إن يصير fertilization هيصير
+
+106
+00:07:33,430 --> 00:07:37,290
+هنا في الـ fallopian tube يبدأ الجسم يفرز هرموناً
+
+107
+00:07:37,290 --> 00:07:41,190
+نسميه هرمون الحمل، وهو عبارة عن الـ beta-human
+
+108
+00:07:41,190 --> 00:07:48,110
+chorionic gonadotropin، بيسموها beta-hCG.
+
+109
+00:07:48,110 --> 00:07:54,290
+اختصار beta-hCG، Human Chorionic Gonadotropin. طبعاً
+
+110
+00:07:54,290 --> 00:08:00,410
+هذا الهرمون يُفرز يُسمى بهرمون الحمل، ويتم إفرازه and
+
+111
+00:08:00,410 --> 00:08:04,850
+its help، يتم إفرازه بمجرد حدوث الـ fertilization من
+
+112
+00:08:04,850 --> 00:08:09,850
+قبل الجسم، وظيفته الأساسية بيحفظ الـ corpus luteum
+
+113
+00:08:09,850 --> 00:08:14,630
+من أجل استمرار إفراز البروجسترون، كمان هذا الـ beta-
+
+114
+00:08:14,630 --> 00:08:19,330
+hCG يحفظ بطانة الرحم إنها تبقى thick ما يصير لها
+
+115
+00:08:19,330 --> 00:08:23,020
+thinning، وبالتالي بيصير لها degradation بشكل سريع.
+
+116
+00:08:23,020 --> 00:08:25,920
+During a pregnancy, all events of the menstrual
+
+117
+00:08:25,920 --> 00:08:30,000
+cycle will be stopped and there is no menstruation.
+
+118
+00:08:30,000 --> 00:08:33,820
+خلال عملية الحمل وإذا صار في fertilization، كل
+
+119
+00:08:33,820 --> 00:08:37,580
+أحداث الدورة الشهرية كلها هتتوقف ومش هيصير a
+
+120
+00:08:37,580 --> 00:08:40,800
+bleeding في نهاية الثمانية والعشرين يوماً، لإنه صار في
+
+121
+00:08:40,800 --> 00:08:45,290
+عندي جنين. والجنين يعني إنغرز في بطانة الرحم، يعني
+
+122
+00:08:45,290 --> 00:08:48,350
+بطانة الرحم لازم تبقى موجودة ومايصلهاش degradation.
+
+123
+00:08:48,350 --> 00:08:51,570
+طب إذا ما صار ش فيه pregnancy كل الهرمونات هذه
+
+124
+00:08:51,570 --> 00:08:55,710
+هتتغير، هيبدأ الـ corpus luteum يوقف إفراز
+
+125
+00:08:55,710 --> 00:09:00,070
+البروجسترون، هيصير فيه shrinkage بشكل تدريجي ويصير له
+
+126
+00:09:00,070 --> 00:09:04,590
+degradation. إفراز هرمون البروجسترون كمان في
+
+127
+00:09:04,590 --> 00:09:09,140
+المقابل يقلل إفراز هرمون الاستروجين. كلهم يلعبوا دوراً
+
+128
+00:09:09,140 --> 00:09:12,500
+سلبياً على بطانة الرحم، مما يؤدي إلى إضعافها
+
+129
+00:09:12,500 --> 00:09:18,180
+وتهتكها وتكسيرها وخروجها مع ال bleeding في نهاية
+
+130
+00:09:18,180 --> 00:09:23,400
+هذا الـ cycle والتي تعتبر بداية cycle جديدة. هذا
+
+131
+00:09:23,400 --> 00:09:24,180
+بالنسبة إلى
+
+132
+00:09:27,980 --> 00:09:32,380
+هنتكلم ببساطة في صورة هي في عين دي hypothalamic
+
+133
+00:09:32,380 --> 00:09:35,560
+وهو عبارة عن الـ hypothalamus اللي بيفرز
+
+134
+00:09:35,560 --> 00:09:38,060
+gonadotropin releasing hormone للناس اللي أخدت
+
+135
+00:09:38,060 --> 00:09:40,880
+endocrinology بأثر على الـ anterior loop
+
+136
+00:09:40,880 --> 00:09:44,040
+للـ pituitary gland، فبيفرز الـ FSH، follicle
+
+137
+00:09:44,040 --> 00:09:48,660
+stimulating hormone، وبيفرز الـ luteinizing hormone. الـ
+
+138
+00:09:48,660 --> 00:09:52,060
+follicle stimulating hormone وظيفته الأساسية بيحفظ
+
+139
+00:09:52,060 --> 00:09:56,500
+الـ follicle للنضوج، للوصول إلى الجريفة الـ
+
+140
+00:09:56,500 --> 00:10:00,470
+Graafian follicle. بمجرد وصول الـ
+
+141
+00:10:00,470 --> 00:10:02,730
+Graafian Follicle إلى الـ Diameter المطلوب من 18
+
+142
+00:10:02,730 --> 00:10:07,930
+-36 ببدأ يفرز كمية كبيرة جدا من الـ Estrogen اللي
+
+143
+00:10:07,930 --> 00:10:10,910
+بحفظ الـ Anterior lobe للـ Pituitary Gland فتفرز الـ
+
+144
+00:10:10,910 --> 00:10:14,970
+Luteinizing Hormone اللي بيعمل Ovulation للفوليكل 
+
+145
+00:10:14,970 --> 00:10:17,890
+هذه اللي صار فيها Ovulation تتحول إلى Corpus
+
+146
+00:10:17,890 --> 00:10:22,490
+Luteum من أجل إفراز هرمون البروجسترون هذه فكرة
+
+147
+00:10:22,490 --> 00:10:27,030
+عملية الدورة الشهرية أو هرمونات الدورة الشهرية
+
+148
+00:10:27,030 --> 00:10:30,890
+عند السيدات خلّينا نشوف الفيديو اللي بتكلم عن هذه
+
+149
+00:10:30,890 --> 00:10:38,190
+العملية الـ
+
+150
+00:10:38,190 --> 00:10:41,470
+The menstrual cycle is a term used to describe monthly
+
+151
+00:10:41,470 --> 00:10:44,130
+events that occur within a woman's body in 
+
+152
+00:10:44,130 --> 00:10:48,270
+preparation for the possibility of pregnancy each
+
+153
+00:10:48,270 --> 00:10:50,570
+month an egg is released from an ovary
+
+154
+00:10:53,700 --> 00:10:58,220
+في نفس الوقت، يتحرر خطوط البرتقال لاستعداد الحضور
+
+155
+00:10:58,220 --> 00:11:03,000
+إذا لم تتحرر الخطوط بالبرتقال لاستعداد الحضور
+
+156
+00:11:03,000 --> 00:11:04,220
+للاستعداد الحضور للاستعداد الحضور للاستعداد الحضور
+
+157
+00:11:04,220 --> 00:11:04,620
+للاستعداد الحضور للاستعداد الحضور للاستعداد الحضور
+
+158
+00:11:04,620 --> 00:11:04,720
+للاستعداد الحضور للاستعداد الحضور للاستعداد الحضور
+
+159
+00:11:04,720 --> 00:11:06,340
+للاستعداد الحضور للاستعداد الحضور للاستعداد الحضور
+
+160
+00:11:06,340 --> 00:11:09,740
+للاستعداد الحضور للاستعداد الحضور للاستعداد الحضور
+
+161
+00:11:09,740 --> 00:11:16,800
+للاستعداد الحضور للاستعداد الحضور للاستعداد
+
+162
+00:11:16,800 --> 00:11:19,760
+الحضور للاستعداد الح
+
+163
+00:11:22,610 --> 00:11:26,010
+المنسوي سايكل يتحكم في الهرمونات التي يتم تحريرها
+
+164
+00:11:26,010 --> 00:11:32,290
+من الجلد والعضلات الجلد الهرموني نفسه يتحكم في
+
+165
+00:11:32,290 --> 00:11:37,150
+الهيبوتلاموس الهيبوتلاموس ينتج هرمون يدعى
+
+166
+00:11:37,150 --> 00:11:44,090
+Gonadotropin Releasing Hormone أو GNRH  GNRH يدفع  جذب
+
+167
+00:11:44,090 --> 00:11:47,670
+الهرمون الهرموني لتحرير الهرمون الهرموني يدفع
+
+168
+00:11:47,670 --> 00:11:53,230
+الهرمون الهرموني لتحرير الـ FSH تسير في مصادر الدم
+
+169
+00:11:53,230 --> 00:11:58,750
+إلى الأعضاء ويعزز مجموعة من الفوليكولات لتنمو هذه
+
+170
+00:11:58,750 --> 00:12:02,330
+الفوليكولات الأساسية تتطور إلى فوليكولات أساسية ثم 
+
+171
+00:12:02,330 --> 00:12:06,710
+فوليكولات ثانوية هذه الفوليكولات تنتج هرمون اسمه
+
+172
+00:12:06,710 --> 00:12:10,350
+أستروجين وهو يعمل لإنشطة تنمو تطور الاندومتريوم
+
+173
+00:12:10,350 --> 00:12:15,190
+البطانة من الجلد الفوليكولات
+
+174
+00:12:15,190 --> 00:12:17,430
+الثانوية تقاتلوا مع بعضها البعض وإلا واحد منهم
+
+175
+00:12:17,430 --> 00:12:22,060
+سيبقى ناضج من الفوليكولات والباقي يتعذب ويموت.
+
+176
+00:12:23,420 --> 00:12:26,200
+مستوى المزيد من الاستروجين يعمل أيضًا على الـ
+
+177
+00:12:26,200 --> 00:12:31,180
+Hypothalamus ومعينة الأمامية لإزالة مستوى الـ GNRH 
+
+178
+00:12:31,180 --> 00:12:37,920
+ويجعله ينتج هرمون آخر، هرمون الـ LH. تشغل تشغف
+
+179
+00:12:37,920 --> 00:12:42,840
+الـ LH تشغّف الـ Ovulation. إطلاق البويضة من
+
+180
+00:12:42,840 --> 00:12:47,200
+الفوليكول والأعضاء. والأجهزة ثم تسحب من الـ Fimbriae
+
+181
+00:12:47,200 --> 00:12:52,120
+ويتخلص من مخصصة الـ Uterine. Fertilization by a
+
+182
+00:12:52,120 --> 00:12:55,540
+spermatozoan when it occurs usually takes place in
+
+183
+00:12:55,540 --> 00:12:58,100
+the ampulla, the widest section of the fallopian
+
+184
+00:12:58,100 --> 00:13:01,660
+tube لذن عملية ال fertilization بتصير في ال
+
+185
+00:13:01,660 --> 00:13:04,740
+Fallopian tube في منطقة بيسموها ال Ampulla في منطقة
+
+186
+00:13:04,740 --> 00:13:09,120
+بيسموها ال Ampulla لأن هذا المصطلح هيمر علينا قدام
+
+187
+00:13:09,120 --> 00:13:11,760
+The fertilized egg immediately begins the process
+
+188
+00:13:11,760 --> 00:13:14,880
+of development while traveling towards the uterus
+
+189
+00:13:14,880 --> 00:13:20,410
+after six days it becomes a blastocyst وهي مصابة في
+
+190
+00:13:20,410 --> 00:13:24,710
+الاندومتريوم في الجلد طبعا بعد كده البويضة
+
+191
+00:13:24,710 --> 00:13:28,210
+المخصبة هتنتقل إلى الرحم وتنغرس في بطانة الرحم في
+
+192
+00:13:28,210 --> 00:13:32,030
+مرحلة معينة إلى أقسام معينة هنتكلم عنه لما نصل إلى ال
+
+193
+00:13:32,030 --> 00:13:37,690
+Embryo Grading و ال Embryo Typing meanwhile the 
+
+194
+00:13:37,690 --> 00:13:40,210
+leftover of the ruptured follicle has become a 
+
+195
+00:13:40,210 --> 00:13:42,930
+corpus luteum which secretes progesterone
+
+196
+00:13:42,930 --> 00:13:46,150
+Progesterone further stimulates uterine
+
+197
+00:13:46,150 --> 00:13:50,440
+development تجعلها مجلد مدعوم للمجلد في حالة
+
+198
+00:13:50,440 --> 00:13:55,620
+الحفاظ على الحمل في حالة مفاوضة الحفاظ على الحمل، يتخلص الكوربوس لوتيوم
+
+199
+00:13:55,620 --> 00:14:01,080
+ويتخلص مستوى البروجسترون هذا يعيد إلى انتقال من
+
+200
+00:14:01,080 --> 00:14:04,760
+الاندومتريوم، يبدأ الانسلال ويبدأ السيكلية بالعكس
+
+201
+00:14:04,760 --> 00:14:11,040
+طبعا
+
+202
+00:14:11,040 --> 00:14:13,720
+هذه الكلام تخلق الدورة الشهرية وأحداث الدورة 
+
+203
+00:14:13,720 --> 00:14:17,970
+الشهرية والهرمونات التي تنتج من الـ Gonadotropin من
+
+204
+00:14:17,970 --> 00:14:20,150
+الـ Hypothalamus متمثل في الـ Gonadotropin الـ
+
+205
+00:14:20,150 --> 00:14:23,230
+Releasing Hormone من الـ Pituitary Gland متمثل في
+
+206
+00:14:23,230 --> 00:14:26,950
+الـ FSH و الـ LH و من ال Corpus Luteum متمثل
+
+207
+00:14:26,950 --> 00:14:32,030
+بالبروجسترون و من ال Follicular متمثل بالـ E2
+
+208
+00:14:32,030 --> 00:14:35,670
+متمثل بالـ E2 طبعا كل هذه الهرمونات مهمة جدا كل
+
+209
+00:14:35,670 --> 00:14:41,180
+واحد له وظيفة معينة مصدر معين وأهمية معينة خلال
+
+210
+00:14:41,180 --> 00:14:46,200
+عملية Menstrual Cycle للوصول إلى Pregnancy Status
+
+211
+00:14:46,200 --> 00:14:51,860
+طبعا هذه شكل ومنحنيات الهرمونات طبعا في عند ال FSH 
+
+212
+00:14:51,860 --> 00:14:54,600
+وال LH يفرز من ال Anterior Lobe للـ Pituitary Gland
+
+213
+00:14:54,600 --> 00:15:01,960
+يفرز ال FSH على شكل مستمر وال LH يفرز ب High 
+
+214
+00:15:01,960 --> 00:15:07,510
+Peak في مرة واحدة فقط لغير وهي عبارة عن لحظة
+
+215
+00:15:07,510 --> 00:15:11,070
+التبويض اللي بتسميها لحظة التبويض وهي الـ LH Wave
+
+216
+00:15:11,070 --> 00:15:16,370
+Triggered for Ovulation هاي المراحل تدور البويضة
+
+217
+00:15:16,370 --> 00:15:19,850
+من Primordial Germ Cell، Primary Oocyte، Secondary 
+
+218
+00:15:19,850 --> 00:15:25,510
+Oocyte، Follicle، Single Follicle، ال Graafian 
+
+219
+00:15:25,510 --> 00:15:29,230
+Follicle، وبعدين ال Ovulation، Corpus Luteum، لما
+
+220
+00:15:29,230 --> 00:15:33,270
+يصير له Degeneration في الـ Luteal Phase
+
+221
+00:15:34,540 --> 00:15:38,760
+الـ Ovarian Hormone أول هرمون يفرز هو الاستروجين
+
+222
+00:15:38,760 --> 00:15:43,680
+لأنه يفرز من البويضات أو الفوليكول التي تبدأ بتطور
+
+223
+00:15:43,680 --> 00:15:48,180
+ونضوج ثم بعد ال Ovulation يبدأ إفراز هرمون 
+
+224
+00:15:48,180 --> 00:15:52,020
+البروجسترون من الكوربوس لوتيوم طبعا هذه المراحل
+
+225
+00:15:52,020 --> 00:15:55,020
+بيصير فيها ال Bleeding أول دورة شهرية بيصير فيها
+
+226
+00:15:55,020 --> 00:15:59,880
+Endometrial Bleeding من خلال تهتك وتمزق بطانة الرحم عملية
+
+227
+00:15:59,880 --> 00:16:02,980
+قبل الـ Ovulation تبدأ الـ Endometrium يصير لها
+
+228
+00:16:02,980 --> 00:16:06,600
+عملية Regeneration مرة أخرى علشان تستقبل البويضة
+
+229
+00:16:06,600 --> 00:16:11,180
+المخصبة البويضة المخصبة في حالة تخزينها بأسفل الرحم
+
+230
+00:16:11,180 --> 00:16:16,580
+طيب في بعض الحالات ممكن يزيد ال Duration خاصة بين
+
+231
+00:16:16,580 --> 00:16:19,800
+ال Menstrual Cycle في بعض الحالات يزيد أكثر لعدة
+
+232
+00:16:19,800 --> 00:16:24,920
+أسباب السبب الأول أنه يصير في عندي عدم انتظام في
+
+233
+00:16:24,920 --> 00:16:27,980
+الهرمونات السبب الأول أنه الهرمونات Out of Work 
+
+234
+00:16:27,980 --> 00:16:32,240
+خارج العمل الهرمونات بتكون Out of Work يعني Out of
+
+235
+00:16:32,240 --> 00:16:36,920
+Control خارج العمل خارج .. خارج قدرة التنظيم و هذا
+
+236
+00:16:36,920 --> 00:16:40,540
+بيصير من خلال الـ PCOS الـ Polycystic Ovarian
+
+237
+00:16:40,540 --> 00:16:44,980
+Syndrome اللي اتكلمنا عليها وهي عبارة عن أن ..
+
+238
+00:16:44,980 --> 00:16:48,780
+عبارة عن خلق .. يعني عبارة عن حالة تؤدي إلى إفقاد
+
+239
+00:16:48,780 --> 00:16:52,700
+المبيض وظيفته يعني بتصير عند الفليل اللي بتنمو و
+
+240
+00:16:52,700 --> 00:16:56,480
+مافيها بويضة ناضجة أو ممكن يكون Under Reacted أو 
+
+241
+00:16:56,480 --> 00:17:02,670
+Over ..Underactive أو Overactive للـ Thyroid Gland
+
+242
+00:17:02,670 --> 00:17:06,030
+اللي بتفرز هرمون الـ Thyroid Hormone and other
+
+243
+00:17:06,030 --> 00:17:11,710
+Disorders that affected in the sex hormone in 
+
+244
+00:17:11,710 --> 00:17:17,390
+Female من أشهرها أو هذه الأمور اللي اتكلمنا عليها
+
+245
+00:17:17,390 --> 00:17:21,990
+سواء كانت الـ PCOS أو زيادة نشاط أو نقصان نشاط
+
+246
+00:17:21,990 --> 00:17:27,560
+هرمون هرمون المفرز من الغدة الدرقية يؤدي إلى زيادة
+
+247
+00:17:27,560 --> 00:17:32,360
+طول الدورة كالوقت اللي تستهلكه بدل سبع أيام أو
+
+248
+00:17:32,360 --> 00:17:35,960
+متوسط خمس أيام تصبح عشرة أو سبعة أو ثمانية وتصبح
+
+249
+00:17:35,960 --> 00:17:40,200
+الدورة Heavy و Irregular أيضا بعض ال Medication
+
+250
+00:17:40,200 --> 00:17:44,960
+إذا كانت السيدة بتاخد Thyroid Medication، Steroid 
+
+251
+00:17:44,960 --> 00:17:51,540
+بعض الأدوية بتعمل على تأثير سلبي على ال Sex 
+
+252
+00:17:51,540 --> 00:17:54,800
+Hormone الخاصة فيها زي الفسادش واللاتشفبالتالي
+
+253
+00:17:54,800 --> 00:17:57,180
+بيغير من طبيعة الدورة، بيغير من ال Evaluation
+
+254
+00:17:57,180 --> 00:18:01,600
+للدورة، عشان كده أي سيدة بتتناول هرمونات اللي هي
+
+255
+00:18:01,600 --> 00:18:04,620
+علاقة بالسترويد هرمون أو بتتناول Medication اللي
+
+256
+00:18:04,620 --> 00:18:08,920
+هي علاقة بالـ Thyroid Medication أو السترويد هرمون،
+
+257
+00:18:08,920 --> 00:18:11,720
+لازم تتأكد من الكمية اللي بتاخدها أو الكيفية اللي
+
+258
+00:18:11,720 --> 00:18:15,820
+بتاخد فيها Exposure to Environmental Estrogen بعض
+
+259
+00:18:15,820 --> 00:18:19,820
+الأحيان بعض السيدات بتتعرض لهرمونات من ال
+
+260
+00:18:19,820 --> 00:18:22,440
+Environment خاصة الهرمونات اللي بتتواجد في ال
+
+261
+00:18:22,440 --> 00:18:27,780
+Plastic Material، Plastic Product، Pesticide
+
+262
+00:18:27,780 --> 00:18:32,800
+تناول لحوم أبقار معالجة بالهرمونات يعني كأنها
+
+263
+00:18:32,800 --> 00:18:37,380
+بتاخد هرمون من مصدر آخر فهذا بيخل الهرمونات داخل
+
+264
+00:18:37,380 --> 00:18:42,980
+الجسم Out of Control فبيغير مدى استجابة الـ Ovary
+
+265
+00:18:42,980 --> 00:18:47,280
+لهذه الهرمونات فبؤدي إلى تغيير طبيعة الدورة من حيث
+
+266
+00:18:47,280 --> 00:18:50,800
+ال Duration أيضًا من الأسباب التي تؤدي إلى زيادة
+
+267
+00:18:50,800 --> 00:18:55,380
+فترة الدورة الدموية اكتساب الوزن أو ال Stress بعض
+
+268
+00:18:55,380 --> 00:18:58,300
+السيدات لو زاد وزنها عن الوزن المطلوب أو الوزن 
+
+269
+00:18:58,300 --> 00:19:01,760
+الصحيح أو الوزن المثالي خلّينا نسميه بناء على ال
+
+270
+00:19:01,760 --> 00:19:04,880
+Body Mass Index يصير فيه عدة Fluctuation أو
+
+271
+00:19:04,880 --> 00:19:08,420
+Irregularity في ال Menstrual Cycle ال Menstrual 
+
+272
+00:19:08,420 --> 00:19:13,600
+Cycle بتكون Irregular أيضا ال Stress القلق يؤدي 
+
+273
+00:19:13,600 --> 00:19:19,800
+إلى إنقاص العمر بشكل حرفي لأن القلق مسؤول عن إنقاص
+
+274
+00:19:19,800 --> 00:19:24,440
+العمر الافتراضي للخلايا هذا كما قلت على مرحلة من
+
+275
+00:19:24,440 --> 00:19:28,160
+ناحية الـ Genetics القلق يؤدي إلى إنقاص التيلوميرات
+
+276
+00:19:28,160 --> 00:19:32,040
+فالتيلوميرات تعمل على إفقاد الخلية قدرتها على البقاء
+
+277
+00:19:32,040 --> 00:19:36,180
+فبصير Destructured أيضا القلق بيعمل Fluctuation في 
+
+278
+00:19:36,180 --> 00:19:39,560
+ال Hormones بشكل عام ومن أشهرهم ال Six Hormones زي
+
+279
+00:19:39,560 --> 00:19:43,240
+ال FSH و ال LH فبيدّي الحالة النفسية إلى فقدان
+
+280
+00:19:43,240 --> 00:19:50,400
+السيدة أو فقدان الزوج الذكر الرغبة في الإنجاب مما 
+
+281
+00:19:50,400 --> 00:19:55,020
+يؤدي إلى تأخر الإنجاب فما بالك هذا على سعيد تأخر
+
+282
+00:19:55,020 --> 00:19:59,020
+الإنجاب كمشكلة عامة فما بالك على سعيد  phases
+
+283
+00:19:59,020 --> 00:20:02,020
+الخاصة بتدورة ممكن تصير fluctuation في مستوى
+
+284
+00:20:02,020 --> 00:20:04,900
+الهرمونات في كمية الهرمونات في كيفية إفراز
+
+285
+00:20:04,900 --> 00:20:09,760
+الهرمونات فبالتالي بيصير في اندي increasing in the
+
+286
+00:20:09,760 --> 00:20:15,300
+duration of menstrual cycle خلصنا من الـ Female و
+
+287
+00:20:15,300 --> 00:20:19,940
+الهرمونات الخاصة بها، سنتحدث عن الهرمون الخاص بال
+
+288
+00:20:19,940 --> 00:20:24,300
+Male هل هناك هرمونات خاصة بال Male Reproductive
+
+289
+00:20:24,300 --> 00:20:28,900
+System مُغيرة عن الهرمونات التي ذُكرت في ال Female؟
+
+290
+00:20:28,900 --> 00:20:31,420
+معظم الهرمونات متشابهة باستثناء الـ Testosterone
+
+291
+00:20:32,880 --> 00:20:37,580
+الذكورة لا يوجد إلا عند الذكور يوجد عند الإناث
+
+292
+00:20:37,580 --> 00:20:42,460
+بكمية قليلة جدا تكاد لا تذكر ولكن يبدأ بالزيادة
+
+293
+00:20:42,460 --> 00:20:46,280
+بعد الـ menstrual cycle عشان كده السيدة بعد سن
+
+294
+00:20:46,280 --> 00:20:51,880
+انقطاع الطمث بيبدأ عندها زيادة في حجم العظم
+
+295
+00:20:51,880 --> 00:20:57,220
+بالإضافة إلى خشونة في الصوت فبالتالي الـ hormones
+
+296
+00:20:57,220 --> 00:20:59,960
+and reproduction in male
+
+297
+00:21:02,970 --> 00:21:05,670
+الـ Gonadotropin-releasing hormone اللي بيأثر على
+
+298
+00:21:05,670 --> 00:21:09,270
+الـ anterior lobe للـ  hypothalamus فبيفرز الـ FSH والـ
+
+299
+00:21:09,270 --> 00:21:14,810
+LH الـ LH يستقبله ريسبتور تقدر بـ 20 ألف ريسبتور
+
+300
+00:21:14,810 --> 00:21:17,510
+موجودة على سطح الـ Leydig cells الموجودة في الـ
+
+301
+00:21:17,510 --> 00:21:21,950
+testes فمجرد إفراز الـ LH من خلال الـ anterior
+
+302
+00:21:21,950 --> 00:21:25,710
+lobe للـ  hypothalamus ينقل عبر الدم إلى الـ Leydig
+
+303
+00:21:25,710 --> 00:21:31,010
+cells الموجودة في الـ testes الخاصة بالذكور هذا الـ
+
+304
+00:21:31,010 --> 00:21:34,310
+LH  يحفظ الـ Leydig cells على 
+
+305
+00:21:34,310 --> 00:21:39,290
+إنتاج الـ testosterone ينتج من ماذا؟ ينتج من مادة مهمة
+
+306
+00:21:39,290 --> 00:21:43,990
+جدا الكوليسترول إذا الكوليسترول هو المكون الأساسي
+
+307
+00:21:43,990 --> 00:21:48,150
+للـ sex hormone بشكل أساسي الـ testosterone بمجرد
+
+308
+00:21:48,150 --> 00:21:50,590
+إفرازه من الـ Leydig cells is released in the blood
+
+309
+00:21:50,590 --> 00:21:55,310
+and is taken to the Sertoli cells بمجرد أن الـ
+
+310
+00:21:55,310 --> 00:21:58,170
+Leydig cells تستقبل الـ LH تفرز الـ testosterone
+
+311
+00:21:58,170 --> 00:22:02,170
+الـ testosterone ينقل عبر الدم إلى مناطق مختلفة من
+
+312
+00:22:02,170 --> 00:22:05,530
+الجسم ويصلها الـ Sertoli cells الموجودة في الـ testes
+
+313
+00:22:05,530 --> 00:22:10,190
+أيضًا بمجرد وصولها إلى الـ Sertoli cells أو وصولها
+
+314
+00:22:10,190 --> 00:22:12,810
+إلى الـ Sertoli cells where it is affected in the
+
+315
+00:22:12,810 --> 00:22:15,570
+secondary sexual tissues يعني بأثر على الـ Sertoli
+
+316
+00:22:15,570 --> 00:22:19,290
+cells و بأثر أيضًا على أنسجة أخرى في الجسم هنتكلم
+
+317
+00:22:19,290 --> 00:22:23,310
+عنها زي مثلًا الـ muscles بيزيد الـ thickness للـ
+
+318
+00:22:23,310 --> 00:22:29,790
+muscles العظم بيزيد كثافة العظم الصوت بيزيد خشونة
+
+319
+00:22:29,790 --> 00:22:33,630
+الصوت عند الذكور أيضًا في بعض المناطق اللي بتعمل
+
+320
+00:22:33,630 --> 00:22:37,830
+على ظهور الصفات الذكورية الثانوية الـ Sertoli cells
+
+321
+00:22:37,830 --> 00:22:42,350
+مهمة جدًا طبعًا بمجرد أنه يصير لها stimulation
+
+322
+00:22:42,350 --> 00:22:47,190
+للـ Sertoli cells بفعل هرمون اسمه FSH تفرز الـ Sertoli
+
+323
+00:22:47,190 --> 00:22:51,280
+cells مادة تسمى Androgen Binding Protein هذا
+
+324
+00:22:51,280 --> 00:22:54,760
+الـ Androgen binding protein يعتبر carrier for
+
+325
+00:22:54,760 --> 00:22:59,220
+الـ testosterone بيرتبط مع الـ testosterone وبيعمل على نقله
+
+326
+00:22:59,220 --> 00:23:03,200
+إلى مناطق مختلفة من أشهرها الـ seminiferous tubules
+
+327
+00:23:03,200 --> 00:23:07,080
+وهو المكان الذي يصنع فيه الـ sperm with its
+
+328
+00:23:07,080 --> 00:23:11,980
+strong influence of the course of spermatogenesis
+
+329
+00:23:11,980 --> 00:23:15,860
+يعني الـ hypothalamus يفرز Gonadotropin Releasing Hormone
+
+330
+00:23:15,860 --> 00:23:19,260
+(GnRH) بأثر على الـ anterior lobe للـ  pituitary gland بتفرز
+
+331
+00:23:19,260 --> 00:23:24,870
+FSH و الـ LH يُنقل إلى الـ Leydig cells ويؤثر عليها
+
+332
+00:23:24,870 --> 00:23:30,930
+تفرز الـ testosterone من الكوليسترول الـ testosterone يُنقل
+
+333
+00:23:30,930 --> 00:23:34,750
+في الدم فيؤثر على الـ Sertoli cells الـ Sertoli cells بتفرز
+
+334
+00:23:34,750 --> 00:23:37,910
+مادة عبارة عن carrier protein بتسمى Androgen
+
+335
+00:23:37,910 --> 00:23:41,950
+Binding Protein يرتبط مع الـ testosterone ويعمل على نقل
+
+336
+00:23:41,950 --> 00:23:46,550
+الـ testosterone إلى مناطق مختلفة طيب الـ Sertoli cells
+
+337
+00:23:46,550 --> 00:23:50,980
+production الـ Sertoli cells تنتج أيضًا نوع آخر من
+
+338
+00:23:50,980 --> 00:23:54,540
+الهرمون يسمى Inhibin طبعًا هذا الـ Inhibin اللي تم
+
+339
+00:23:54,540 --> 00:23:58,620
+إفرازه من الـ Sertoli cells إلى الـ anterior lobe للـ  pituitary gland وممكنًا إلى
+
+340
+00:23:58,620 --> 00:24:03,120
+الـ hypothalamus الـ Inhibin يعمل كعامل مُنظم  لإيقاف
+
+341
+00:24:03,120 --> 00:24:09,400
+إفراز الـ FSH طبعًا بمجرد أن الـ Sertoli cells تتأثر
+
+342
+00:24:09,400 --> 00:24:12,800
+بالتستوستيرون هتفرز الـ carrier protein اللي اسمه
+
+343
+00:24:12,800 --> 00:24:16,120
+Androgen Binding Protein اللي بيرتبط مع الـ
+
+344
+00:24:16,120 --> 00:24:19,700
+Testosterone وينقله إلى مناطق مختلفة من الجسم أهمها
+
+345
+00:24:19,700 --> 00:24:21,900
+الـ seminiferous tubules الموجودة في الـ Testis
+
+346
+00:24:21,900 --> 00:24:26,240
+اللي تعتبر مصنع الـ spermatocytes أيضًا الـ
+
+347
+00:24:26,240 --> 00:24:29,280
+Sertoli cells لا تكتفي بهذا الأمر بل تقوم بإفراز
+
+348
+00:24:29,280 --> 00:24:33,300
+هرمون آخر اسمه الـ Inhibin هذا الـ Inhibin هو المُنظم
+
+349
+00:24:33,300 --> 00:24:37,180
+الذي  ممكن يصل إلى الـ anterior lobe للـ  pituitary gland
+
+350
+00:24:37,180 --> 00:24:41,540
+وإلى الـ hypothalamus ويعمل لهم shutdown بمعنى آخر
+
+351
+00:24:41,540 --> 00:24:45,860
+ليس shutdown completelyلأ، بيعمل إيقاف لإفراز هرمون
+
+352
+00:24:45,860 --> 00:24:49,800
+الـ FSH طيب، what is the function أو what is the
+
+353
+00:24:49,800 --> 00:24:52,580
+major function of Sertoli cells؟ أول حاجة بتعمل
+
+354
+00:24:52,580 --> 00:24:56,840
+maintenance لـ blood-testis barrier الحواجز
+
+355
+00:24:56,840 --> 00:25:00,480
+الموجودة بين الدورة الدموية و الـ testes المسئولة عن الـ
+
+356
+00:25:00,480 --> 00:25:04,240
+maintenance الخاصة بها الـ Sertoli cells وإلا، حيصير
+
+357
+00:25:04,240 --> 00:25:07,820
+في direct contact ما بين blood circulation و الـ
+
+358
+00:25:07,820 --> 00:25:12,420
+testes ويعمل الجسم Antibody ضد الـ sperm، ضد نفسه أي
+
+359
+00:25:12,420 --> 00:25:15,580
+شيء .. شغلة ثانية Secretion of tubular fluid مهم
+
+360
+00:25:15,580 --> 00:25:18,900
+جدا Secretion of Androgen Binding Protein اللي
+
+361
+00:25:18,900 --> 00:25:22,360
+تحدثنا فيها قبل بشوية Secretion of estrogen and
+
+362
+00:25:22,360 --> 00:25:25,300
+Inhibin و الـ Inhibin مهم جدا في عملية الـ regulation
+
+363
+00:25:25,300 --> 00:25:30,360
+Secretion of a wide number of other proteins vary
+
+364
+00:25:30,360 --> 00:25:36,140
+growth factors Transferrin بالإضافة إلى هرمون آخر مثلًا
+
+365
+00:25:36,140 --> 00:25:41,180
+binding protein هذا مهم جدا Maintenance and
+
+366
+00:25:41,510 --> 00:25:44,450
+coordination of spermatogenesis بتعمل maintenance
+
+367
+00:25:44,450 --> 00:25:49,010
+لعملية الـ spermatogenesis وبتعمل تنظيم متى ينتقل
+
+368
+00:25:49,010 --> 00:25:53,470
+من الـ type A إلى type B للـ spermatocyte لسه 
+
+369
+00:25:53,470 --> 00:25:56,830
+كان spermatocyte هذا كله مسئولة على الـ Sertoli
+
+370
+00:25:56,830 --> 00:26:00,130
+cells عشان كده الـ Sertoli cells قلنا في البداية أن
+
+371
+00:26:00,130 --> 00:26:04,270
+one Sertoli cell تستطيع أن تدعم إنتاج 50 من 
+
+372
+00:26:04,270 --> 00:26:09,000
+30 إلى 50 spermatocytes أو sperm Phagocytosis of
+
+373
+00:26:09,000 --> 00:26:12,620
+residual bodies of sperm cells مسئولة عنها الـ Sertoli cells
+
+374
+00:26:12,620 --> 00:26:16,800
+فالـ Sertoli cells لها أكثر من function خلينا نشوف
+
+375
+00:26:16,800 --> 00:26:22,980
+الفيديو اللي بيتكلم عن الهرمون الخاص بالذكور وكيف
+
+376
+00:26:22,980 --> 00:26:30,520
+مسئولة عن إنتاج الـ spermatocytes Testosterone
+
+377
+00:26:30,520 --> 00:26:31,000
+production
+
+378
+00:26:34,110 --> 00:26:37,490
+الـ Hypothalamus تطلع Gonadotropin Releasing Hormone تطلع الهرمون أو
+
+379
+00:26:37,490 --> 00:26:42,670
+GnRH في حركة كل 60 إلى 90 دقيقة لتشغيل تطلع
+
+380
+00:26:42,670 --> 00:26:49,710
+الهرمون الـ LH من الـ anterior lobe إلى الدم الـ LH
+
+381
+00:26:49,710 --> 00:26:53,570
+يُجمع على الـ Leydig cells للـ testes
+
+382
+00:26:56,150 --> 00:26:58,670
+Binding initiates a cascade of events, which
+
+383
+00:26:58,670 --> 00:27:01,610
+include the conversion of cholesterol, depicted as
+
+384
+00:27:01,610 --> 00:27:05,050
+LDL here, to pregnenolone, followed by a series of
+
+385
+00:27:05,050 --> 00:27:07,810
+reactions, which convert pregnenolone to
+
+386
+00:27:07,810 --> 00:27:12,050
+testosterone Testosterone
+
+387
+00:27:12,050 --> 00:27:14,750
+secreted by the testes diffuses into the
+
+388
+00:27:14,750 --> 00:27:17,190
+peripheral circulation to be carried to target
+
+389
+00:27:17,190 --> 00:27:24,310
+tissues In liver .. طبعًا في بعض ال .. ال .. ال ..
+
+390
+00:27:24,310 --> 00:27:24,630
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+391
+00:27:24,630 --> 00:27:25,030
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+392
+00:27:25,030 --> 00:27:25,930
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+393
+00:27:25,930 --> 00:27:25,950
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+394
+00:27:25,950 --> 00:27:27,680
+ال .. ال .. ال .. المعادلة مش مطالبين فيها In
+
+395
+00:27:27,680 --> 00:27:30,700
+genital and adipose tissue testosterone binds
+
+396
+00:27:30,700 --> 00:27:34,380
+directly to its androgen receptor or AR to exert
+
+397
+00:27:34,380 --> 00:27:38,840
+its biological effect In skin, hair, the prostate
+
+398
+00:27:38,840 --> 00:27:42,460
+gland and gonadal tissue testosterone must be
+
+399
+00:27:42,460 --> 00:27:46,660
+converted to dihydrotestosterone or DHT by 5
+
+400
+00:27:46,660 --> 00:27:49,440
+alpha reductase in order to bind the androgen
+
+401
+00:27:49,440 --> 00:27:55,060
+receptor In bone and brain, testosterone is
+
+402
+00:27:55,060 --> 00:27:55,720
+converted by
+
+403
+00:28:00,140 --> 00:28:04,400
+وينتقل إلى مستقبلات الإستروجين E2R ليُحدث تأثيره
+
+404
+00:28:06,740 --> 00:28:09,920
+هذا بالنسبة إلى الهرمونات التي لها علاقة بالذكور
+
+405
+00:28:09,920 --> 00:28:14,180
+بشكل أساسي كيف تُفرز و من أين تُفرز و كيف تساهم في
+
+406
+00:28:14,180 --> 00:28:18,300
+العملية هذه الصورة تُؤكد العملية مرة أخرى هي عند
+
+407
+00:28:18,300 --> 00:28:20,720
+الـ hypothalamus وهو عبارة عن الـ master gland
+
+408
+00:28:20,720 --> 00:28:25,080
+الخاص بالجسم بتحكم بكل شيء له علاقة بالجسم يفرز
+
+409
+00:28:25,080 --> 00:28:28,120
+هرمون اسمه Gonadotropin Releasing Hormone اللي
+
+410
+00:28:28,120 --> 00:28:30,700
+بينتقل إلى الـ anterior lobe للـ  pituitary gland هذا
+
+411
+00:28:30,700 --> 00:28:33,960
+اللون الأبيض الـ anterior lobe وهذا اللون الغامق الـ posterior lobe
+
+412
+00:28:34,990 --> 00:28:38,770
+طبعًا بيتكلم إنه في عندي أسهم باللون الأحمر دائمًا
+
+413
+00:28:38,770 --> 00:28:43,370
+بتعمل enhancing بتعمل stimulation واللي باللون الـ
+
+414
+00:28:43,370 --> 00:28:46,770
+bare ball بتعمل depression أو بتعمل reduction أو
+
+415
+00:28:46,770 --> 00:28:51,470
+بتعمل feedback يعني كأنها بتعمل عملية إنقاص في
+
+416
+00:28:51,470 --> 00:28:55,490
+كمية الهرمون المُفرز إذا بتعمل inhibitor إذا اللي
+
+417
+00:28:55,490 --> 00:28:58,310
+بالأحمر بتعمل stimulation واللي بالـ bare ball
+
+418
+00:28:58,310 --> 00:29:01,690
+بتعمل inhibition طبعًا Gonadotropin Releasing Hormone
+
+419
+00:29:01,690 --> 00:29:04,910
+بيأثر على الـ anterior lobe للـ pituitary gland بيفرز
+
+420
+00:29:04,910 --> 00:29:09,310
+الـ FSH وبيفرز الـ LH الـ LH يُنقل إلى الـ Target 
+
+421
+00:29:09,310 --> 00:29:11,930
+Cell وهي الـ Leading Cell لأن الـ Receptor موجود
+
+422
+00:29:11,930 --> 00:29:15,290
+على سطحها فبتفرز هرمون الـ Testosterone الـ
+
+423
+00:29:15,290 --> 00:29:18,750
+Testosterone يُنطقى .. يُنقل إلى مناطق مختلفة من
+
+424
+00:29:18,750 --> 00:29:23,430
+أجل إظهار الصفات الذكورية الثانوية فيُنقل إلى
+
+425
+00:29:23,430 --> 00:29:26,630
+البرستاتا، يُنقل إلى ال muscles، يُنقل إلى
+
+426
+00:29:26,630 --> 00:29:29,610
+الepidermis، يُنقل إلى ال seminal vesicles وخلافه
+
+427
+00:29:29,980 --> 00:29:33,420
+كمان ينقل إلى الـ Sertoli cell فيحفظ الـ Sertoli cell
+
+428
+00:29:33,420 --> 00:29:37,000
+تحت 
+
+429
+00:29:37,000 --> 00:29:42,180
+تأثير الـ FSH-Hormone ستفرز مادة بسميها Androgen
+
+430
+00:29:42,180 --> 00:29:46,500
+Binding Protein  الـ Androgen Binding Protein برتبط 
+
+431
+00:29:46,500 --> 00:29:49,520
+مع الـ Testosterone وبينقله إلى الـ
+
+432
+00:29:49,520 --> 00:29:54,140
+Seminiferous tubule المسؤول عن إنتاج الـ
+
+433
+00:29:54,140 --> 00:29:58,540
+spermatocyte طب خلص وظيفتها أيضًا السيرتولى سيل
+
+434
+00:29:58,540 --> 00:30:02,160
+طالما خلصت وظيفتها هتفرز هرمون اسمه الانهيبين
+
+435
+00:30:02,160 --> 00:30:05,180
+باللون البربول فبتأثر على الـ anterior lobe و
+
+436
+00:30:05,180 --> 00:30:08,280
+الباتيوترجلاند بتعملها negative feedback و بتأثر
+
+437
+00:30:08,280 --> 00:30:13,000
+على الhypothalamus أيضًا التستسترون قد وظيفته 
+
+438
+00:30:13,000 --> 00:30:16,560
+هيشتغل على الhypothalamus فيعمله negative
+
+439
+00:30:16,560 --> 00:30:20,460
+inhibition أو inhibitor وعلى ال anterior lobe
+
+440
+00:30:20,460 --> 00:30:25,980
+للباتيوترجلاندبالإضافة إلى إن الـ Sertoli cell بعد ما
+
+441
+00:30:25,980 --> 00:30:29,500
+تخلص الوظيفة المطلوبة منها ويكون أفرزة الكمية 
+
+442
+00:30:29,500 --> 00:30:32,560
+المطلوبة من الهرمونات المسؤولة عن تصنيع الـ
+
+443
+00:30:32,560 --> 00:30:36,420
+spermatozoa تعمل على إفراز هرمون اسمه الـ Estrogen
+
+444
+00:30:36,420 --> 00:30:39,920
+leading cell stimulating factor هذا الـ Estrogen
+
+445
+00:30:39,920 --> 00:30:47,170
+يعمل أيضًا على تحفيز الـ leading cell لإستمرار
+
+446
+00:30:47,170 --> 00:30:50,850
+إفراز الـ testosterone عند الحاجة أو يفبطها عند
+
+447
+00:30:50,850 --> 00:30:55,050
+انتهاء الوظيفة المطلوبة منها إذا في عندي two
+
+448
+00:30:55,050 --> 00:30:58,950
+arrows red for stimulation و purple for inhibitor
+
+449
+00:30:58,950 --> 00:31:01,470
+نفس الهرمون ممكن يعمل inhibition و يعمل
+
+450
+00:31:01,470 --> 00:31:05,970
+stimulation أو ممكن هرمون آخر يفرز من نفس ال cells
+
+451
+00:31:05,970 --> 00:31:09,250
+من أجل عمل inhibition للـhypothalamus و
+
+452
+00:31:09,250 --> 00:31:14,900
+الانتيرويوب أوبهذا القدر نقوم انتهينا من ال
+
+453
+00:31:14,900 --> 00:31:18,720
+chapter الأول ان شاء الله على أمل أن نستكمل في
+
+454
+00:31:18,720 --> 00:31:23,060
+المحاضرات القادمة بأم الله، دومتم في حفظ الله
+
+455
+00:31:23,060 --> 00:31:24,280
+ورعايته 
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/e8zUWOaK1rw_raw.json b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/e8zUWOaK1rw_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..b06708f5bea4cbf3ad751c829322c3e0c9eff512
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/e8zUWOaK1rw_raw.json
@@ -0,0 +1 @@
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{"start": 705.51, "end": 705.83, "word": " a", "probability": 0.9853515625}, {"start": 705.83, "end": 706.09, "word": " new", "probability": 0.8740234375}, {"start": 706.09, "end": 706.51, "word": " chance", "probability": 0.96875}, {"start": 706.51, "end": 706.71, "word": " for", "probability": 0.875}, {"start": 706.71, "end": 707.39, "word": " fertilization", "probability": 0.937744140625}, {"start": 707.39, "end": 708.99, "word": " بمجرد", "probability": 0.9779296875}, {"start": 708.99, "end": 709.29, "word": " أنه", "probability": 0.66064453125}, {"start": 709.29, "end": 709.81, "word": " يبدأ", "probability": 0.9930013020833334}, {"start": 709.81, "end": 711.11, "word": " الكوربسليوتن", "probability": 0.7095075334821429}, {"start": 711.11, "end": 711.27, "word": " في", "probability": 0.93798828125}, {"start": 711.27, "end": 711.37, "word": " ال", "probability": 0.9755859375}, {"start": 711.37, "end": 711.93, "word": " degradation", "probability": 0.9248046875}, {"start": 711.93, 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okay by the 22 to 24 of menstrual cycle يعني بمعنى أخر أن هذه العملية و هذه ال atrophy تبدأ بتصير", "tokens": [3555, 22488, 29910, 23275, 30731, 2423, 39184, 22272, 6367, 295, 264, 10147, 1983, 822, 43284, 6225, 8592, 7649, 6055, 44510, 10721, 11778, 13063, 3660, 10874, 16254, 41891, 9154, 11933, 5172, 2288, 31377, 2423, 479, 17308, 16070, 43, 39, 6225, 8592, 7649, 37495, 9566, 1829, 22653, 11778, 13063, 3660, 13412, 3224, 2288, 10632, 10874, 16254, 41891, 4032, 25957, 1211, 10632, 11933, 3555, 18513, 3660, 10874, 16254, 41891, 10874, 16254, 41891, 3714, 15042, 7251, 38251, 5016, 4724, 24401, 23328, 21542, 42213, 3714, 14851, 4587, 3555, 15040, 14111, 293, 309, 311, 1392, 538, 264, 5853, 281, 4022, 295, 38827, 304, 6586, 37495, 22653, 4724, 2304, 3615, 1863, 7578, 5551, 34740, 14739, 29538, 18863, 42213, 10632, 4032, 29538, 2423, 412, 40826, 6055, 44510, 10721, 39894, 9381, 13546], "avg_logprob": -0.20816531621160045, "compression_ratio": 1.5970695970695972, "no_speech_prob": 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"end": 1077.65, "word": " كاملا", "probability": 0.9677734375}, {"start": 1077.65, "end": 1078.11, "word": " من", "probability": 0.859375}, {"start": 1078.11, "end": 1078.47, "word": " حصول", "probability": 0.9842122395833334}, {"start": 1078.47, "end": 1079.35, "word": " نواة", "probability": 0.7317708333333334}, {"start": 1079.35, "end": 1080.07, "word": " واحدة", "probability": 0.9720052083333334}, {"start": 1080.07, "end": 1080.45, "word": " هنا", "probability": 0.391845703125}, {"start": 1080.45, "end": 1081.03, "word": " بسميها", "probability": 0.937255859375}, {"start": 1081.03, "end": 1082.05, "word": " fertilized", "probability": 0.840576171875}, {"start": 1082.05, "end": 1082.99, "word": " oocyte", "probability": 0.8505859375}, {"start": 1082.99, "end": 1083.97, "word": " fertilized", "probability": 0.720947265625}, {"start": 1083.97, "end": 1084.99, "word": " oocyte", "probability": 0.98095703125}, {"start": 1084.99, "end": 1085.27, "word": " يعني", "probability": 0.908935546875}, {"start": 1085.27, "end": 1085.91, "word": " بويضة", "probability": 0.9228515625}, {"start": 1085.91, "end": 1086.87, "word": " مخصمة", "probability": 0.842041015625}, {"start": 1086.87, "end": 1088.25, "word": " ال", "probability": 0.673828125}, {"start": 1088.25, "end": 1088.55, "word": " corona", "probability": 0.331298828125}, {"start": 1088.55, "end": 1089.19, "word": " radiata", "probability": 0.918212890625}, {"start": 1089.19, "end": 1089.73, "word": " هي", "probability": 0.93359375}, {"start": 1089.73, "end": 1090.15, "word": " عبارة", "probability": 0.99658203125}, {"start": 1090.15, "end": 1090.37, "word": " عن", "probability": 0.99853515625}, {"start": 1090.37, "end": 1090.77, "word": " خلايا", "probability": 0.88671875}, {"start": 1090.77, "end": 1091.17, "word": " تحيط", "probability": 0.897705078125}, {"start": 1091.17, "end": 1091.37, "word": " بالـ", "probability": 0.837158203125}, {"start": 1091.37, "end": 1091.89, "word": " oocyte", "probability": 0.91015625}], "temperature": 1.0}, {"id": 42, "seek": 110507, "start": 1092.25, "end": 1105.07, "text": "with a high cellular layer with an intracellular matrix consist of يعني هي عبارة عن خلايا محيطة بالـ Oocyte من الخارج ولكن ال matrix في الداخل التابع الخاص فيها يحتوي على مواد أخرى", "tokens": [11820, 257, 1090, 29267, 4583, 365, 364, 17467, 617, 285, 1040, 8141, 4603, 295, 37495, 22653, 39896, 6225, 3555, 9640, 3660, 18871, 16490, 15040, 25528, 3714, 5016, 1829, 9566, 3660, 20666, 39184, 422, 31078, 975, 9154, 33962, 9640, 7435, 35525, 19452, 2423, 8141, 8978, 32748, 47283, 1211, 16712, 16758, 3615, 2423, 9778, 33546, 8978, 11296, 7251, 33753, 45865, 15844, 3714, 14407, 3215, 5551, 34740, 7578], "avg_logprob": -0.2232481065121564, "compression_ratio": 1.4285714285714286, "no_speech_prob": 1.9669532775878906e-06, "words": [{"start": 1092.25, "end": 1092.55, "word": "with", "probability": 0.36328125}, {"start": 1092.55, "end": 1092.79, "word": " a", "probability": 0.94970703125}, 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important role", "tokens": [6027, 26890, 35473, 9957, 11622, 4724, 8592, 28820, 5551, 3794, 32277, 1829, 2423, 1090, 9856, 295, 47048, 293, 2477, 304, 374, 11630, 8258, 16490, 3215, 14407, 20666, 4117, 9673, 14407, 3215, 29538, 3714, 16095, 3660, 10874, 28259, 5296, 31377, 2304, 6055, 30544, 8978, 11296, 5296, 33456, 11296, 39894, 17082, 8848, 29739, 45865, 11242, 3660, 4724, 8592, 28820, 5551, 3794, 32277, 1829, 8978, 9673, 23557, 5016, 1211, 16247, 12610, 7578, 9154, 6225, 42213, 10632, 2423, 3803, 8167, 309, 307, 983, 7847, 300, 2477, 304, 374, 266, 327, 651, 1974, 420, 4736, 490, 264, 1378, 295, 257, 32899, 862, 257, 588, 1021, 3090], "avg_logprob": -0.18504901610168756, "compression_ratio": 1.4872727272727273, "no_speech_prob": 3.5762786865234375e-07, "words": [{"start": 1107.59, "end": 1108.49, "word": "البروتينز", "probability": 0.76435546875}, {"start": 1108.49, "end": 1108.89, "word": " بشكل", "probability": 0.9055989583333334}, {"start": 1108.89, "end": 1109.45, "word": " 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"seek": 124720, "start": 1218.66, "end": 1247.2, "text": "بشرحها و نسمعها و نشوفها في فيديو ان شاء الله اذا عملية ال penetration تعتمد على نقطتين أساسيتين افراز انزيم يعمل على الهيارونك أسد الهيارونك أسد بيشتغل عليه و ال movement اللي تحدث في ال sperm من خلال ال swimming من خلال ال swimming اخترق ال sperm ال corona radiata بعد كده لازم يواجه", "tokens": [3555, 46309, 5016, 11296, 4032, 8717, 38251, 3615, 11296, 4032, 8717, 8592, 38688, 11296, 8978, 8978, 16254, 2407, 16472, 13412, 16606, 21984, 1975, 15730, 6225, 42213, 10632, 2423, 35187, 6055, 34268, 2304, 3215, 15844, 8717, 47432, 2655, 9957, 5551, 3794, 32277, 36081, 9957, 1975, 5172, 2288, 31377, 16472, 11622, 32640, 7251, 25957, 1211, 15844, 2423, 3224, 1829, 9640, 11536, 4117, 5551, 3794, 3215, 2423, 3224, 1829, 9640, 11536, 4117, 5551, 3794, 3215, 4724, 1829, 8592, 2655, 17082, 1211, 47356, 4032, 2423, 3963, 13672, 1829, 6055, 24401, 12984, 8978, 2423, 32899, 9154, 16490, 1211, 6027, 2423, 11989, 9154, 16490, 1211, 6027, 2423, 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عن زونافليوسيدا، so the sperm should be penetrated the zoonapelucida after attachment with the receptor", "tokens": [6027, 5016, 16373, 9566, 6024, 95, 34740, 34051, 9673, 7649, 3615, 6024, 95, 34740, 10874, 16606, 9154, 4032, 7251, 36520, 5296, 19528, 18513, 3660, 2423, 13063, 5718, 104, 10632, 13672, 1829, 16490, 33546, 3660, 20666, 3555, 45865, 11242, 3660, 37037, 15730, 9673, 7649, 3615, 7251, 38251, 7578, 1176, 35, 37037, 2407, 6225, 3555, 9640, 3660, 18871, 30767, 2407, 8315, 5172, 20292, 41779, 25708, 995, 12399, 370, 264, 32899, 820, 312, 16183, 5468, 264, 710, 4106, 569, 338, 1311, 2887, 934, 19431, 365, 264, 32264], "avg_logprob": -0.3246323515387142, "compression_ratio": 1.4285714285714286, "no_speech_prob": 4.172325134277344e-07, "words": [{"start": 1247.75, "end": 1248.37, "word": "الحائط", "probability": 0.8236083984375}, {"start": 1248.37, "end": 1248.93, "word": " الآخر", "probability": 0.7582194010416666}, {"start": 1248.93, "end": 1249.17, "word": " أو", 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بتصير و إلا ممكن أحطن بوايض ال human مثلا بوايض الطائر نطف تعتبط خاصة بطائر معين أو بحيوان معين و هذا شيء غير منطقي فبالتالي في رسبتور مهم جدا علشان يصير في عندي", "tokens": [2278, 5925, 260, 36052, 295, 1176, 4106, 404, 9527, 4032, 41185, 12602, 3794, 3555, 2655, 13063, 15844, 2423, 39184, 422, 31078, 975, 5551, 4117, 25708, 8978, 12602, 3794, 3555, 2655, 13063, 4032, 20193, 9122, 33911, 39894, 9381, 13546, 8978, 3224, 14739, 3224, 18871, 16254, 8717, 45367, 9154, 14739, 14407, 3615, 16712, 9778, 9381, 9381, 10632, 34051, 33962, 9381, 2407, 9381, 10632, 2423, 2685, 507, 9122, 33911, 39894, 9381, 13546, 4032, 11933, 15040, 3714, 43020, 5551, 5016, 9566, 1863, 4724, 14407, 1829, 11242, 2423, 1952, 50113, 15040, 4724, 14407, 1829, 11242, 41950, 16373, 2288, 8717, 9566, 5172, 6055, 34268, 3555, 9566, 16490, 33546, 3660, 4724, 9566, 16373, 2288, 20449, 9957, 34051, 4724, 5016, 1829, 2407, 7649, 20449, 9957, 4032, 23758, 44049, 38207, 32771, 13546, 9154, 9566, 38436, 6156, 3555, 6027, 2655, 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1354.79, "word": " attached", "probability": 0.8515625}, {"start": 1354.79, "end": 1355.39, "word": " with", "probability": 0.87353515625}, {"start": 1355.39, "end": 1355.65, "word": " the", "probability": 0.87109375}, {"start": 1355.65, "end": 1356.45, "word": " polypeptide", "probability": 0.958984375}, {"start": 1356.45, "end": 1356.87, "word": " core", "probability": 0.9580078125}, {"start": 1356.87, "end": 1357.13, "word": " of", "probability": 0.97216796875}, {"start": 1357.13, "end": 1357.17, "word": " the", "probability": 0.58935546875}, {"start": 1357.17, "end": 1357.89, "word": " zoonopelucida", "probability": 0.63037109375}, {"start": 1357.89, "end": 1358.87, "word": " molecule", "probability": 0.73876953125}, {"start": 1358.87, "end": 1359.47, "word": " بمعنى", "probability": 0.952734375}, {"start": 1359.47, "end": 1359.95, "word": " آخر", "probability": 0.7421875}, {"start": 1359.95, "end": 1360.57, "word": " أنه", "probability": 0.5516357421875}, {"start": 1360.57, "end": 1360.81, "word": " عشان", "probability": 0.9793294270833334}, {"start": 1360.81, "end": 1361.13, "word": " يصير", "probability": 0.9228515625}, {"start": 1361.13, "end": 1361.83, "word": " penetration", "probability": 0.921875}, {"start": 1361.83, "end": 1363.27, "word": " للـOocyte", "probability": 0.621435546875}, {"start": 1363.27, "end": 1363.45, "word": " أو", "probability": 0.94921875}, {"start": 1363.45, "end": 1364.27, "word": " للـZoonopelucida", "probability": 0.845458984375}, {"start": 1364.27, "end": 1365.07, "word": " لازم", "probability": 0.86572265625}, {"start": 1365.07, "end": 1365.23, "word": " ال", "probability": 0.87744140625}, {"start": 1365.23, "end": 1365.85, "word": " sperm", "probability": 0.67431640625}, {"start": 1365.85, "end": 1366.91, "word": " ينسك", "probability": 0.9208984375}, {"start": 1366.91, "end": 1367.07, "word": " في", "probability": 0.93798828125}, {"start": 1367.07, "end": 1367.59, "word": " منطقة", "probability": 0.9601236979166666}, {"start": 1367.59, "end": 1368.29, "word": " معينة", "probability": 0.9903971354166666}], "temperature": 1.0}, {"id": 53, "seek": 139205, "start": 1368.59, "end": 1392.05, "text": "لا تتواجد إلا في الـ zoonabulucida 3 تسمى الـ silica acid molecule يعني كأن الـ sperm متخصص بالارتباط بالـ silica acid molecule الموجود في zoonabulucida 3 والذي مرتبط بالـ polypeptide core of zoonabulucida 3 بشكل أساسي", "tokens": [15040, 6055, 2655, 2407, 26108, 3215, 11933, 15040, 8978, 2423, 39184, 710, 4106, 14057, 1311, 2887, 805, 6055, 38251, 7578, 2423, 39184, 3425, 2262, 8258, 15582, 37495, 22653, 9122, 33456, 2423, 39184, 32899, 44650, 9778, 9381, 9381, 20666, 9640, 2655, 3555, 41193, 20666, 39184, 3425, 2262, 8258, 15582, 9673, 29245, 23328, 8978, 710, 4106, 14057, 1311, 2887, 805, 16070, 8848, 1829, 3714, 43500, 3555, 9566, 20666, 39184, 6754, 494, 662, 482, 4965, 295, 710, 4106, 14057, 1311, 2887, 805, 4724, 8592, 28820, 5551, 3794, 32277, 1829], "avg_logprob": -0.23096264333560548, "compression_ratio": 1.618279569892473, "no_speech_prob": 1.1920928955078125e-06, "words": [{"start": 1368.59, "end": 1368.91, "word": "لا", "probability": 0.6318359375}, {"start": 1368.91, "end": 1369.69, "word": " تتواجد", "probability": 0.97470703125}, {"start": 1369.69, "end": 1370.15, "word": " إلا", "probability": 0.92919921875}, {"start": 1370.15, "end": 1370.55, "word": " في", "probability": 0.9833984375}, {"start": 1370.55, "end": 1370.87, "word": " الـ", "probability": 0.7017822265625}, {"start": 1370.87, "end": 1371.45, "word": " zoonabulucida", "probability": 0.4450927734375}, {"start": 1371.45, "end": 1371.85, "word": " 3", "probability": 0.347412109375}, {"start": 1371.85, "end": 1372.77, "word": " تسمى", "probability": 0.84375}, {"start": 1372.77, "end": 1373.01, "word": " الـ", "probability": 0.6126708984375}, {"start": 1373.01, "end": 1373.35, "word": " silica", "probability": 0.753173828125}, {"start": 1373.35, "end": 1373.81, "word": " acid", "probability": 0.88134765625}, {"start": 1373.81, "end": 1374.47, "word": " molecule", "probability": 0.8251953125}, {"start": 1374.47, "end": 1375.25, "word": " يعني", "probability": 0.810546875}, {"start": 1375.25, "end": 1375.79, "word": " كأن", "probability": 0.828369140625}, {"start": 1375.79, "end": 1376.13, "word": " الـ", "probability": 0.59326171875}, {"start": 1376.13, "end": 1376.59, "word": " sperm", "probability": 0.89990234375}, {"start": 1376.59, "end": 1377.91, "word": " متخصص", "probability": 0.9884033203125}, {"start": 1377.91, "end": 1378.85, "word": " بالارتباط", "probability": 0.9107421875}, {"start": 1378.85, "end": 1379.11, "word": " بالـ", "probability": 0.827880859375}, {"start": 1379.11, "end": 1379.47, "word": " silica", "probability": 0.9599609375}, {"start": 1379.47, "end": 1381.49, "word": " acid", "probability": 0.7734375}, {"start": 1381.49, "end": 1383.71, "word": " molecule", "probability": 0.75732421875}, {"start": 1383.71, "end": 1384.57, "word": " الموجود", "probability": 0.9544270833333334}, {"start": 1384.57, "end": 1385.39, "word": " في", "probability": 0.97607421875}, {"start": 1385.39, "end": 1387.05, "word": " zoonabulucida", "probability": 0.855322265625}, {"start": 1387.05, "end": 1387.57, "word": " 3", "probability": 0.8662109375}, {"start": 1387.57, "end": 1388.85, "word": " والذي", "probability": 0.6184895833333334}, {"start": 1388.85, "end": 1389.27, "word": " مرتبط", "probability": 0.98828125}, {"start": 1389.27, "end": 1389.47, "word": " بالـ", "probability": 0.864990234375}, {"start": 1389.47, "end": 1390.03, "word": " polypeptide", "probability": 0.83648681640625}, {"start": 1390.03, "end": 1390.35, "word": " core", "probability": 0.90283203125}, {"start": 1390.35, "end": 1390.51, "word": " of", "probability": 0.32177734375}, {"start": 1390.51, "end": 1391.03, "word": " zoonabulucida", "probability": 0.9478515625}, {"start": 1391.03, "end": 1391.25, "word": " 3", "probability": 0.75537109375}, {"start": 1391.25, "end": 1391.57, "word": " بشكل", "probability": 0.9754231770833334}, {"start": 1391.57, "end": 1392.05, "word": " أساسي", "probability": 0.97607421875}], "temperature": 1.0}, {"id": 54, "seek": 141556, "start": 1392.66, "end": 1415.56, "text": "بشكل أساسي موجودة في أو مرتبط بهذا الـ Silic Acid في الـ Poly-Tied Core of Zoonopelucid-3 ميكيول on the surface of sperm head are specific binding site of Zoonopelucid-3 sperm receptor on the Zoonopelucid So what is the meaning of this paragraph؟ ببساطة إن الـ sperm", "tokens": [3555, 8592, 28820, 5551, 3794, 32277, 1829, 3714, 29245, 23328, 3660, 8978, 34051, 3714, 43500, 3555, 9566, 39627, 15730, 2423, 39184, 6943, 299, 5097, 327, 8978, 2423, 39184, 18553, 12, 51, 1091, 14798, 295, 1176, 4106, 404, 338, 1311, 327, 12, 18, 3714, 1829, 4117, 1829, 12610, 322, 264, 3753, 295, 32899, 1378, 366, 2685, 17359, 3621, 295, 1176, 4106, 404, 338, 1311, 327, 12, 18, 32899, 32264, 322, 264, 1176, 4106, 404, 338, 1311, 327, 407, 437, 307, 264, 3620, 295, 341, 18865, 22807, 4724, 3555, 3794, 41193, 3660, 36145, 2423, 39184, 32899], "avg_logprob": -0.3789473822242335, "compression_ratio": 1.3793103448275863, "no_speech_prob": 1.1920928955078125e-07, "words": [{"start": 1392.66, "end": 1393.0, "word": "بشكل", "probability": 0.86767578125}, {"start": 1393.0, "end": 1393.56, "word": " أساسي", "probability": 0.9752197265625}, {"start": 1393.56, "end": 1394.64, "word": " موجودة", "probability": 0.73492431640625}, {"start": 1394.64, "end": 1394.98, "word": " في", "probability": 0.454345703125}, {"start": 1394.98, "end": 1395.32, "word": " أو", "probability": 0.689453125}, {"start": 1395.32, "end": 1395.72, "word": " مرتبط", "probability": 0.9688720703125}, {"start": 1395.72, "end": 1395.92, "word": " بهذا", "probability": 0.571533203125}, {"start": 1395.92, "end": 1395.98, "word": " الـ", "probability": 0.892333984375}, {"start": 1395.98, "end": 1396.18, "word": " Silic", "probability": 0.47869873046875}, {"start": 1396.18, "end": 1396.48, "word": " Acid", "probability": 0.7412109375}, {"start": 1396.48, "end": 1396.76, "word": " في", "probability": 0.9013671875}, {"start": 1396.76, "end": 1397.06, "word": " الـ", "probability": 0.759765625}, {"start": 1397.06, "end": 1397.28, "word": " Poly", "probability": 0.24755859375}, {"start": 1397.28, "end": 1398.34, "word": "-Tied", "probability": 0.20231119791666666}, {"start": 1398.34, "end": 1398.74, "word": " Core", "probability": 0.587890625}, {"start": 1398.74, "end": 1399.0, "word": " of", "probability": 0.83544921875}, {"start": 1399.0, "end": 1399.84, "word": " Zoonopelucid", "probability": 0.6239827473958334}, {"start": 1399.84, "end": 1400.48, "word": "-3", "probability": 0.517333984375}, {"start": 1400.48, "end": 1402.12, "word": " ميكيول", "probability": 0.4823974609375}, {"start": 1402.12, "end": 1402.26, "word": " on", "probability": 0.181640625}, {"start": 1402.26, "end": 1402.42, "word": " the", "probability": 0.908203125}, {"start": 1402.42, "end": 1402.74, "word": " surface", "probability": 0.92431640625}, {"start": 1402.74, "end": 1402.9, "word": " of", "probability": 0.98193359375}, {"start": 1402.9, "end": 1403.3, "word": " sperm", "probability": 0.68408203125}, {"start": 1403.3, "end": 1403.62, "word": " head", "probability": 0.50634765625}, {"start": 1403.62, "end": 1404.0, "word": " are", "probability": 0.89599609375}, {"start": 1404.0, "end": 1404.52, "word": " specific", "probability": 0.7392578125}, {"start": 1404.52, "end": 1404.94, "word": " binding", "probability": 0.82666015625}, {"start": 1404.94, "end": 1405.24, "word": " site", "probability": 0.732421875}, {"start": 1405.24, "end": 1405.4, "word": " of", "probability": 0.92529296875}, {"start": 1405.4, "end": 1405.9, "word": " Zoonopelucid", "probability": 0.9342447916666666}, {"start": 1405.9, "end": 1406.28, "word": "-3", "probability": 0.932373046875}, {"start": 1406.28, "end": 1407.14, "word": " sperm", "probability": 0.70458984375}, {"start": 1407.14, "end": 1407.84, "word": " receptor", "probability": 0.796875}, {"start": 1407.84, "end": 1408.16, "word": " on", "probability": 0.9111328125}, {"start": 1408.16, "end": 1408.34, "word": " the", "probability": 0.84423828125}, {"start": 1408.34, "end": 1409.2, "word": " Zoonopelucid", "probability": 0.8939615885416666}, {"start": 1409.2, "end": 1409.98, "word": " So", "probability": 0.2261962890625}, {"start": 1409.98, "end": 1410.36, "word": " what", "probability": 0.4951171875}, {"start": 1410.36, "end": 1410.48, "word": " is", "probability": 0.412353515625}, {"start": 1410.48, "end": 1410.56, "word": " the", "probability": 0.8994140625}, {"start": 1410.56, "end": 1410.78, "word": " meaning", "probability": 0.88037109375}, {"start": 1410.78, "end": 1411.06, "word": " of", "probability": 0.97900390625}, {"start": 1411.06, "end": 1411.64, "word": " this", "probability": 0.9189453125}, {"start": 1411.64, "end": 1413.92, "word": " paragraph؟", "probability": 0.760009765625}, {"start": 1413.92, "end": 1414.64, "word": " ببساطة", "probability": 0.97705078125}, {"start": 1414.64, "end": 1415.0, "word": " إن", "probability": 0.325927734375}, {"start": 1415.0, "end": 1415.24, "word": " الـ", "probability": 0.79833984375}, {"start": 1415.24, "end": 1415.56, "word": " sperm", "probability": 0.87548828125}], "temperature": 1.0}, {"id": 55, "seek": 143405, "start": 1416.25, "end": 1434.05, "text": "بيبحث عن منطقة في الـ Zoonabolista 3 فقط لغير هي عبارة عن الـ Receptor لأنها تحتوي على مادة يختص فيها ولا يتعرف إلا عليها لـ sperm مثلا تسمى Silic Acid، هذا الـ Silic Acid الـ attachment و الـ polypeptide core الموجود في الـ Zoonabolista", "tokens": [21292, 49628, 12984, 18871, 9154, 9566, 28671, 8978, 2423, 39184, 1176, 4106, 14923, 5236, 805, 6156, 47432, 5296, 17082, 13546, 39896, 6225, 3555, 9640, 3660, 18871, 2423, 39184, 1300, 1336, 284, 5296, 33456, 11296, 6055, 33753, 45865, 15844, 3714, 18513, 3660, 7251, 46456, 9381, 8978, 11296, 49429, 7251, 2655, 3615, 28480, 11933, 15040, 25894, 11296, 5296, 39184, 32899, 50113, 15040, 6055, 38251, 7578, 6943, 299, 5097, 327, 12399, 23758, 2423, 39184, 6943, 299, 5097, 327, 2423, 39184, 19431, 4032, 2423, 39184, 6754, 494, 662, 482, 4965, 9673, 29245, 23328, 8978, 2423, 39184, 1176, 4106, 14923, 5236], "avg_logprob": -0.28302191704818885, "compression_ratio": 1.5350877192982457, "no_speech_prob": 6.556510925292969e-07, "words": [{"start": 1416.25, "end": 1416.91, "word": "بيبحث", "probability": 0.8963216145833334}, {"start": 1416.91, "end": 1417.37, "word": " عن", "probability": 0.99365234375}, {"start": 1417.37, "end": 1418.15, "word": " منطقة", "probability": 0.9601236979166666}, {"start": 1418.15, "end": 1418.53, "word": " في", "probability": 0.93212890625}, {"start": 1418.53, "end": 1418.65, "word": " الـ", "probability": 0.77685546875}, {"start": 1418.65, "end": 1419.23, "word": " Zoonabolista", "probability": 0.4758148193359375}, {"start": 1419.23, "end": 1419.51, "word": " 3", "probability": 0.386962890625}, {"start": 1419.51, "end": 1419.97, "word": " فقط", "probability": 0.977783203125}, {"start": 1419.97, "end": 1420.43, "word": " لغير", "probability": 0.9674479166666666}, {"start": 1420.43, "end": 1421.17, "word": " هي", "probability": 0.44384765625}, {"start": 1421.17, "end": 1421.59, "word": " عبارة", "probability": 0.9884033203125}, {"start": 1421.59, "end": 1421.73, "word": " عن", "probability": 0.99755859375}, {"start": 1421.73, "end": 1421.91, "word": " الـ", "probability": 0.92529296875}, {"start": 1421.91, "end": 1422.41, "word": " Receptor", "probability": 0.7456868489583334}, {"start": 1422.41, "end": 1422.87, "word": " لأنها", "probability": 0.8889973958333334}, {"start": 1422.87, "end": 1423.35, "word": " تحتوي", "probability": 0.9874674479166666}, {"start": 1423.35, "end": 1423.55, "word": " على", "probability": 0.85986328125}, {"start": 1423.55, "end": 1424.07, "word": " مادة", "probability": 0.9881184895833334}, {"start": 1424.07, "end": 1424.87, "word": " يختص", "probability": 0.9816080729166666}, {"start": 1424.87, "end": 1425.21, "word": " فيها", "probability": 0.989501953125}, {"start": 1425.21, "end": 1425.41, "word": " ولا", "probability": 0.65966796875}, {"start": 1425.41, "end": 1425.93, "word": " يتعرف", "probability": 0.9765625}, {"start": 1425.93, "end": 1426.21, "word": " إلا", "probability": 0.673828125}, {"start": 1426.21, "end": 1426.53, "word": " عليها", "probability": 0.85498046875}, {"start": 1426.53, "end": 1426.67, "word": " لـ", "probability": 0.6845703125}, {"start": 1426.67, "end": 1427.05, "word": " sperm", "probability": 0.74169921875}, {"start": 1427.05, "end": 1427.55, "word": " مثلا", "probability": 0.94140625}, {"start": 1427.55, "end": 1428.49, "word": " تسمى", "probability": 0.93994140625}, {"start": 1428.49, "end": 1428.85, "word": " Silic", "probability": 0.398681640625}, {"start": 1428.85, "end": 1429.59, "word": " Acid،", "probability": 0.604248046875}, {"start": 1429.59, "end": 1429.75, "word": " هذا", "probability": 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"probability": 0.6904296875}, {"start": 1433.63, "end": 1434.05, "word": " Zoonabolista", "probability": 0.88330078125}], "temperature": 1.0}, {"id": 56, "seek": 145696, "start": 1434.44, "end": 1456.96, "text": "يعني تشتغل هذه المنطقة كـ Receptor وهي موجودة هيرقبط فيها ب sperm تمهيدة لعملية إفراز الإنزيمات الهاضمة للـ Zona Pellucida طيب، before binding to the Zona Pellucida ممانيا الـ spermatozoa undergo to a chromosomal reaction طبعا جابل", "tokens": [40228, 22653, 6055, 8592, 2655, 17082, 1211, 29538, 9673, 1863, 9566, 28671, 9122, 39184, 1300, 1336, 284, 37037, 1829, 3714, 29245, 23328, 3660, 39896, 2288, 4587, 3555, 9566, 8978, 11296, 4724, 32899, 46811, 3224, 25708, 3660, 5296, 25957, 1211, 10632, 11933, 5172, 2288, 31377, 33688, 1863, 11622, 32640, 9307, 2423, 3224, 46958, 46007, 24976, 39184, 1176, 4037, 430, 898, 1311, 2887, 23032, 1829, 3555, 12399, 949, 17359, 281, 264, 1176, 4037, 430, 898, 1311, 2887, 3714, 2304, 7649, 25528, 2423, 39184, 32899, 2513, 4765, 64, 26426, 281, 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"word": " chromosomal", "probability": 0.8821614583333334}, {"start": 1454.66, "end": 1455.1, "word": " reaction", "probability": 0.92626953125}, {"start": 1455.1, "end": 1455.52, "word": " طبعا", "probability": 0.8870849609375}, {"start": 1455.52, "end": 1456.96, "word": " جابل", "probability": 0.6366373697916666}], "temperature": 1.0}, {"id": 57, "seek": 147641, "start": 1458.13, "end": 1476.41, "text": "ما يتم الإرتباط و قبل ما يصل إلى الـ receptor و يصير فيه إرتباط بشكل واضح و قوي لازم يصير عند الـ sperm full active و لشأن يصير الـ sperm full active يعني لازم يكون قادر على إفراز الإنزيمات المقلوبة تحت مصطلح", "tokens": [15042, 7251, 39237, 33688, 43500, 3555, 41193, 4032, 12174, 36150, 19446, 7251, 36520, 30731, 2423, 39184, 32264, 4032, 7251, 9381, 13546, 8978, 3224, 11933, 43500, 3555, 41193, 4724, 8592, 28820, 4032, 46958, 5016, 4032, 12174, 45865, 5296, 31377, 2304, 7251, 9381, 13546, 43242, 2423, 39184, 32899, 1577, 4967, 4032, 5296, 8592, 33456, 7251, 9381, 13546, 2423, 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reaction؟ وشو هو الـ acrosomal reaction؟ الـ acrosomal reaction سلسلة من التفاعلات بتصير على الـ acrosome الموجود في مقدمة الـ head للـ sperm تمهيدا لإفراز محتويات الـ physical التي تحتوي على الإنزيمات الغاضبة كيف تبدأ؟ في البداية", "tokens": [10721, 4117, 32887, 11622, 20498, 6027, 5480, 6055, 3555, 13412, 2407, 4724, 1829, 9381, 13546, 8978, 2423, 39184, 696, 2635, 298, 304, 5480, 22807, 4032, 8592, 2407, 31439, 2423, 39184, 696, 2635, 298, 304, 5480, 22807, 2423, 39184, 696, 2635, 298, 304, 5480, 8608, 1211, 3794, 37977, 9154, 16712, 5172, 995, 30241, 9307, 39894, 9381, 13546, 15844, 2423, 39184, 696, 2635, 423, 9673, 29245, 23328, 8978, 3714, 28543, 46007, 2423, 39184, 1378, 24976, 39184, 32899, 46811, 3224, 25708, 995, 5296, 28814, 5172, 2288, 31377, 3714, 33753, 45865, 9307, 2423, 39184, 4001, 38392, 6055, 33753, 45865, 15844, 33688, 1863, 11622, 32640, 9307, 6024, 118, 46958, 49401, 9122, 33911, 6055, 44510, 10721, 22807, 8978, 29739, 28259, 10632], "avg_logprob": 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"text": "في بداية تطور الـ acrosome reaction بيصير في عندي حاجة بيسموها massive influx of calcium شو يعني massive؟ يعني without ATP influx خروج، تدفق يعني كأنه الكالسيوم الموجود في الـ head of the sperm أو الموجود في الـ acrosome يخرج نحو الخارج بشكل تلقائي CA plus 2 through the plasma membrane of the sperm head", "tokens": [41185, 4724, 28259, 10632, 6055, 9566, 13063, 2423, 39184, 696, 2635, 423, 5480, 4724, 1829, 9381, 13546, 8978, 18871, 16254, 11331, 26108, 3660, 4724, 1829, 38251, 2407, 11296, 5994, 9922, 2449, 295, 20918, 13412, 2407, 37495, 22653, 5994, 22807, 37495, 22653, 1553, 39202, 9922, 2449, 16490, 2288, 29245, 12399, 6055, 3215, 5172, 4587, 37495, 22653, 9122, 33456, 3224, 33251, 6027, 3794, 1829, 20498, 9673, 29245, 23328, 8978, 2423, 39184, 1378, 295, 264, 32899, 34051, 9673, 29245, 23328, 8978, 2423, 39184, 696, 2635, 423, 7251, 34740, 7435, 8717, 5016, 2407, 33962, 9640, 7435, 4724, 8592, 28820, 6055, 1211, 4587, 16373, 1829, 22852, 1804, 568, 807, 264, 22564, 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للسوديوم و efflux للهيدروجين يعني كأنه مجرد ما يبدأ ال reaction الكالسيوم هيطلع من جهة إسبانيا", "tokens": [3224, 15730, 2423, 26890, 2407, 3794, 1829, 11622, 13672, 1829, 3714, 4587, 9381, 23328, 8978, 11296, 9922, 2449, 34051, 9922, 2449, 9122, 3555, 13546, 9154, 33251, 6027, 3794, 1829, 20498, 9154, 10874, 3224, 3660, 11933, 35457, 7649, 25528, 7251, 30544, 3714, 9381, 39319, 3555, 3224, 3714, 3555, 33599, 25720, 9922, 2449, 24976, 3794, 23328, 1829, 20498, 4032, 1244, 75, 2449, 24976, 3224, 25708, 2288, 29245, 9957, 37495, 22653, 9122, 33456, 3224, 3714, 7435, 2288, 3215, 19446, 7251, 44510, 10721, 2423, 5480, 2423, 4117, 6027, 3794, 1829, 20498, 39896, 9566, 1211, 3615, 9154, 10874, 3224, 3660, 11933, 35457, 7649, 25528], "avg_logprob": -0.2651562577486038, "compression_ratio": 1.7619047619047619, "no_speech_prob": 4.172325134277344e-07, "words": [{"start": 1525.11, "end": 1525.63, "word": "هذا", "probability": 0.40618896484375}, {"start": 1525.63, "end": 1526.21, "word": " 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this process caused exocytosis of the acrosomal vesicle هذه مهمة جدا، خروج الكالسوم، خروج السوديوم", "tokens": [3224, 1829, 9566, 1211, 3615, 20449, 3224, 21136, 23328, 1829, 20498, 49374, 15042, 2423, 3224, 25708, 2288, 29245, 9957, 39896, 3215, 9778, 1211, 11778, 47283, 1211, 2423, 39184, 1378, 295, 3797, 33962, 2288, 29245, 16070, 2655, 3215, 5172, 4587, 9922, 2449, 16070, 3215, 9778, 12610, 1244, 75, 2449, 23758, 4724, 1829, 25957, 1211, 5662, 24976, 39184, 17467, 617, 285, 1040, 21677, 341, 1399, 7008, 454, 905, 4328, 8211, 295, 264, 696, 2635, 298, 304, 28274, 3520, 29538, 3714, 16095, 3660, 10874, 28259, 12399, 16490, 2288, 29245, 33251, 6027, 3794, 20498, 12399, 16490, 2288, 29245, 21136, 23328, 1829, 20498], "avg_logprob": -0.27020200936481203, "compression_ratio": 1.5347826086956522, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 1546.32, "end": 1546.88, "word": "هيطلع", "probability": 0.6952392578125}, {"start": 1546.88, "end": 1547.18, "word": " معه", 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"صار في عنده اختلاف هل الـ DNA الخاص في الـ metacondria الموجود في الأجنة تتبع ال male و لا يتبع ال female بمعنى أخر خاص بالأب paterna ولا خاص بالأم materna وهذا كان نقطة خلاف كبير جدا ما بين العلماء على هذا الموضوع ولكن الموضوع أنه في حاجة اسمها autophage system بتعمل engulfing لل paterna الميتاكندريا الدياني إن دخلت الcytoplasma عشان كده جدا نادر ما بتشوف", "tokens": [9381, 9640, 8978, 43242, 3224, 1975, 46456, 15040, 5172, 8032, 1211, 2423, 39184, 8272, 33962, 33546, 8978, 2423, 39184, 1131, 326, 684, 4668, 9673, 29245, 23328, 8978, 16247, 7435, 1863, 3660, 6055, 2655, 3555, 3615, 2423, 7133, 4032, 20193, 7251, 2655, 3555, 3615, 2423, 6556, 4724, 2304, 3615, 1863, 7578, 5551, 34740, 16490, 33546, 20666, 10721, 3555, 42302, 629, 49429, 16490, 33546, 20666, 10721, 2304, 2389, 629, 37037, 15730, 25961, 8717, 47432, 3660, 16490, 15040, 5172, 9122, 3555, 13546, 10874, 28259, 19446, 49374, 18863, 19528, 16606, 15844, 23758, 9673, 2407, 11242, 45367, 35525, 19452, 9673, 2407, 11242, 45367, 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2173.39, "end": 2173.61, "word": " DNA", "probability": 0.401123046875}, {"start": 2173.61, "end": 2173.99, "word": " الخاص", "probability": 0.95263671875}, {"start": 2173.99, "end": 2174.13, "word": " في", "probability": 0.75048828125}, {"start": 2174.13, "end": 2174.25, "word": " الـ", "probability": 0.83251953125}, {"start": 2174.25, "end": 2174.85, "word": " metacondria", "probability": 0.62646484375}, {"start": 2174.85, "end": 2175.33, "word": " الموجود", "probability": 0.9104817708333334}, {"start": 2175.33, "end": 2175.49, "word": " في", "probability": 0.9765625}, {"start": 2175.49, "end": 2176.11, "word": " الأجنة", "probability": 0.78662109375}, {"start": 2176.11, "end": 2176.97, "word": " تتبع", "probability": 0.80419921875}, {"start": 2176.97, "end": 2177.13, "word": " ال", "probability": 0.82568359375}, {"start": 2177.13, "end": 2177.47, "word": " male", "probability": 0.7333984375}, {"start": 2177.47, "end": 2177.83, "word": " و", "probability": 0.64208984375}, {"start": 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2182.53, "end": 2183.65, "word": " materna", "probability": 0.84375}, {"start": 2183.65, "end": 2184.29, "word": " وهذا", "probability": 0.6900634765625}, {"start": 2184.29, "end": 2184.51, "word": " كان", "probability": 0.984375}, {"start": 2184.51, "end": 2184.85, "word": " نقطة", "probability": 0.986328125}, {"start": 2184.85, "end": 2185.23, "word": " خلاف", "probability": 0.9591471354166666}, {"start": 2185.23, "end": 2185.65, "word": " كبير", "probability": 0.9840494791666666}, {"start": 2185.65, "end": 2185.99, "word": " جدا", "probability": 0.966552734375}, {"start": 2185.99, "end": 2186.17, "word": " ما", "probability": 0.83837890625}, {"start": 2186.17, "end": 2186.37, "word": " بين", "probability": 0.9931640625}, {"start": 2186.37, "end": 2186.89, "word": " العلماء", "probability": 0.9327799479166666}, {"start": 2186.89, "end": 2187.43, "word": " على", "probability": 0.88671875}, {"start": 2187.43, "end": 2187.69, "word": " هذا", "probability": 0.96044921875}, {"start": 2187.69, "end": 2188.05, "word": " الموضوع", "probability": 0.9986572265625}, {"start": 2188.05, "end": 2189.49, "word": " ولكن", "probability": 0.75146484375}, {"start": 2189.49, "end": 2190.17, "word": " الموضوع", "probability": 0.9683837890625}, {"start": 2190.17, "end": 2190.49, "word": " أنه", "probability": 0.51611328125}, {"start": 2190.49, "end": 2190.57, "word": " في", "probability": 0.90625}, {"start": 2190.57, "end": 2190.89, "word": " حاجة", "probability": 0.9890950520833334}, {"start": 2190.89, "end": 2191.33, "word": " اسمها", "probability": 0.9508463541666666}, {"start": 2191.33, "end": 2192.25, "word": " autophage", "probability": 0.7425130208333334}, {"start": 2192.25, "end": 2193.07, "word": " system", "probability": 0.9296875}, {"start": 2193.07, "end": 2193.73, "word": " بتعمل", "probability": 0.8077799479166666}, {"start": 2193.73, "end": 2194.51, "word": " engulfing", "probability": 0.8955078125}, {"start": 2194.51, "end": 2194.71, "word": " لل", "probability": 0.8291015625}, {"start": 2194.71, "end": 2195.27, "word": " paterna", "probability": 0.6678466796875}, {"start": 2195.27, "end": 2196.11, "word": " الميتاكندريا", "probability": 0.7733677455357143}, {"start": 2196.11, "end": 2196.53, "word": " الدياني", "probability": 0.7630615234375}, {"start": 2196.53, "end": 2196.81, "word": " إن", "probability": 0.79638671875}, {"start": 2196.81, "end": 2197.25, "word": " دخلت", "probability": 0.98583984375}, {"start": 2197.25, "end": 2197.95, "word": " الcytoplasma", "probability": 0.6157470703125}, {"start": 2197.95, "end": 2198.37, "word": " عشان", "probability": 0.8347981770833334}, {"start": 2198.37, "end": 2198.57, "word": " كده", "probability": 0.9256184895833334}, {"start": 2198.57, "end": 2199.07, "word": " جدا", "probability": 0.91796875}, {"start": 2199.07, "end": 2199.61, "word": " نادر", "probability": 0.9850260416666666}, {"start": 2199.61, "end": 2199.71, "word": " ما", "probability": 0.923828125}, {"start": 2199.71, "end": 2200.23, "word": " بتشوف", "probability": 0.8997395833333334}], "temperature": 1.0}, {"id": 84, "seek": 222650, "start": 2200.7, "end": 2226.5, "text": "الـ Paternal Mitochondrial في البشر الـ sperm تشغّل الـ Centrosome اللي محتاجه لتنزيف الجسد موجود في المادة الوراثية للأب بشكل أساسي مهم جدا علشان يكمل عملية الغسام الخاصة بالجنين ال paternal mitochondrial اللي حكينا فيها اندخلت خلال عملية ال fertilization ووصلت لها", "tokens": [6027, 39184, 430, 771, 4660, 376, 3528, 339, 684, 7111, 8978, 29739, 46309, 2423, 39184, 32899, 6055, 8592, 17082, 11703, 1211, 2423, 39184, 3408, 2635, 423, 13672, 1829, 3714, 33753, 26108, 3224, 5296, 2655, 1863, 11622, 33911, 25724, 3794, 3215, 3714, 29245, 23328, 8978, 9673, 18513, 3660, 2423, 13063, 5718, 104, 10632, 24976, 10721, 3555, 4724, 8592, 28820, 5551, 3794, 32277, 1829, 3714, 16095, 10874, 28259, 11203, 8592, 7649, 7251, 24793, 1211, 6225, 42213, 10632, 6024, 118, 3794, 10943, 33962, 33546, 3660, 20666, 7435, 1863, 9957, 2423, 42302, 4660, 41008, 7111, 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2204.56, "end": 2205.1, "word": " الـ", "probability": 0.5411376953125}, {"start": 2205.1, "end": 2206.22, "word": " Centrosome", "probability": 0.683349609375}, {"start": 2206.22, "end": 2206.68, "word": " اللي", "probability": 0.630126953125}, {"start": 2206.68, "end": 2207.42, "word": " محتاجه", "probability": 0.5396728515625}, {"start": 2207.42, "end": 2208.44, "word": " لتنزيف", "probability": 0.39384765625}, {"start": 2208.44, "end": 2208.52, "word": " الجسد", "probability": 0.2906494140625}, {"start": 2208.52, "end": 2210.04, "word": " موجود", "probability": 0.6999918619791666}, {"start": 2210.04, "end": 2210.76, "word": " في", "probability": 0.7841796875}, {"start": 2210.76, "end": 2212.76, "word": " المادة", "probability": 0.77197265625}, {"start": 2212.76, "end": 2213.12, "word": " الوراثية", "probability": 0.802587890625}, {"start": 2213.12, "end": 2213.56, "word": " للأب", "probability": 0.8411458333333334}, {"start": 2213.56, "end": 2215.04, "word": " بشكل", "probability": 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"word": " mitochondrial", "probability": 0.86962890625}, {"start": 2221.94, "end": 2222.06, "word": " اللي", "probability": 0.79931640625}, {"start": 2222.06, "end": 2222.38, "word": " حكينا", "probability": 0.9833984375}, {"start": 2222.38, "end": 2222.7, "word": " فيها", "probability": 0.973876953125}, {"start": 2222.7, "end": 2223.5, "word": " اندخلت", "probability": 0.92021484375}, {"start": 2223.5, "end": 2223.98, "word": " خلال", "probability": 0.9677734375}, {"start": 2223.98, "end": 2224.36, "word": " عملية", "probability": 0.99169921875}, {"start": 2224.36, "end": 2224.62, "word": " ال", "probability": 0.904296875}, {"start": 2224.62, "end": 2225.72, "word": " fertilization", "probability": 0.873046875}, {"start": 2225.72, "end": 2226.26, "word": " ووصلت", "probability": 0.9625244140625}, {"start": 2226.26, "end": 2226.5, "word": " لها", "probability": 0.785400390625}], "temperature": 1.0}, {"id": 85, "seek": 224930, "start": 2226.96, "end": 2249.3, "text": "الـfertilized oocyte أو الـCytoplasma الخاص بالـfertilized oocyte هتلاقي مباشرة فيه إلها elimination يعني بتترد أو بيصيلها breakdown أو degeneration بفعل إنزين يسميه autophagocyte و لكن الطريقة و الميكنزم حتى الآن في عندي limitation", "tokens": [6027, 39184, 612, 20007, 1602, 277, 31078, 975, 34051, 2423, 39184, 34, 4328, 404, 7743, 1696, 33962, 33546, 20666, 39184, 612, 20007, 1602, 277, 31078, 975, 8032, 2655, 15040, 38436, 3714, 3555, 33599, 25720, 8978, 3224, 11933, 1211, 11296, 29224, 37495, 22653, 39894, 2655, 2288, 3215, 34051, 4724, 1829, 9381, 1829, 1211, 11296, 18188, 34051, 368, 30372, 4724, 5172, 30241, 36145, 11622, 9957, 7251, 38251, 1829, 3224, 1476, 5317, 559, 31078, 975, 4032, 44381, 41950, 16572, 28671, 4032, 9673, 1829, 19452, 11622, 2304, 11331, 49975, 6024, 48506, 8978, 18871, 16254, 27432], "avg_logprob": -0.34765624125366623, "compression_ratio": 1.509009009009009, "no_speech_prob": 8.940696716308594e-07, "words": [{"start": 2226.96, "end": 2228.48, "word": "الـfertilized", "probability": 0.59775390625}, {"start": 2228.48, "end": 2229.12, "word": " oocyte", "probability": 0.7762044270833334}, {"start": 2229.12, "end": 2229.64, "word": " أو", "probability": 0.65576171875}, {"start": 2229.64, "end": 2230.36, "word": " الـCytoplasma", "probability": 0.7323346819196429}, {"start": 2230.36, "end": 2230.68, "word": " الخاص", "probability": 0.981689453125}, {"start": 2230.68, "end": 2231.32, "word": " بالـfertilized", "probability": 0.794140625}, {"start": 2231.32, "end": 2232.26, "word": " oocyte", "probability": 0.966796875}, {"start": 2232.26, "end": 2232.76, "word": " هتلاقي", "probability": 0.83892822265625}, {"start": 2232.76, "end": 2233.48, "word": " مباشرة", "probability": 0.9744873046875}, {"start": 2233.48, "end": 2234.22, "word": " فيه", "probability": 0.4764404296875}, {"start": 2234.22, "end": 2234.4, "word": " إلها", "probability": 0.5847981770833334}, {"start": 2234.4, "end": 2235.16, "word": " elimination", "probability": 0.8857421875}, {"start": 2235.16, "end": 2235.74, "word": " يعني", "probability": 0.7763671875}, {"start": 2235.74, "end": 2236.4, "word": " بتترد", "probability": 0.72705078125}, {"start": 2236.4, "end": 2236.78, "word": " أو", "probability": 0.92041015625}, {"start": 2236.78, "end": 2237.42, "word": " بيصيلها", "probability": 0.6940511067708334}, {"start": 2237.42, "end": 2237.82, "word": " breakdown", "probability": 0.85400390625}, {"start": 2237.82, "end": 2238.38, "word": " أو", "probability": 0.62060546875}, {"start": 2238.38, "end": 2239.3, "word": " degeneration", "probability": 0.59686279296875}, {"start": 2239.3, "end": 2240.26, "word": " بفعل", "probability": 0.9152018229166666}, {"start": 2240.26, "end": 2240.68, "word": " إنزين", "probability": 0.6590169270833334}, {"start": 2240.68, "end": 2241.3, "word": " يسميه", "probability": 0.6641845703125}, {"start": 2241.3, "end": 2242.7, "word": " autophagocyte", "probability": 0.815966796875}, {"start": 2242.7, "end": 2244.1, "word": " و", "probability": 0.246826171875}, {"start": 2244.1, "end": 2244.38, "word": " لكن", "probability": 0.73388671875}, {"start": 2244.38, "end": 2245.42, "word": " الطريقة", "probability": 0.9440104166666666}, {"start": 2245.42, "end": 2245.6, "word": " و", "probability": 0.72021484375}, {"start": 2245.6, "end": 2246.3, "word": " الميكنزم", "probability": 0.64658203125}, {"start": 2246.3, "end": 2246.82, "word": " حتى", "probability": 0.9248046875}, {"start": 2246.82, "end": 2247.22, "word": " الآن", "probability": 0.824462890625}, {"start": 2247.22, "end": 2247.66, "word": " في", "probability": 0.6474609375}, {"start": 2247.66, "end": 2248.12, "word": " عندي", "probability": 0.787353515625}, {"start": 2248.12, "end": 2249.3, "word": " limitation", "probability": 0.7783203125}], "temperature": 1.0}, {"id": 86, "seek": 227983, "start": 2254.85, "end": 2279.83, "text": "المتوفرة عن هذا السبب أو عن هذه القالية The inheritance of metachondria اتفق العلماء أن معظم الـ metachondrial في أجسادنا 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{"start": 2403.71, "end": 2403.99, "word": " واحدة", "probability": 0.9763997395833334}, {"start": 2403.99, "end": 2404.43, "word": " paternal", "probability": 0.982666015625}, {"start": 2404.43, "end": 2404.51, "word": " ..", "probability": 0.60205078125}, {"start": 2404.51, "end": 2405.75, "word": " متكندرية", "probability": 0.97880859375}, {"start": 2405.75, "end": 2405.95, "word": " او", "probability": 0.677978515625}, {"start": 2405.95, "end": 2406.13, "word": " لاجوا", "probability": 0.9514973958333334}, {"start": 2406.13, "end": 2407.47, "word": " تلاتة", "probability": 0.9794921875}, {"start": 2407.47, "end": 2407.59, "word": " ..", "probability": 0.3466796875}, {"start": 2407.59, "end": 2407.81, "word": " واحدة", "probability": 0.9718424479166666}, {"start": 2407.81, "end": 2408.11, "word": " خاصة", "probability": 0.98388671875}, {"start": 2408.11, "end": 2408.41, "word": " بالأب", "probability": 0.9466145833333334}, {"start": 2408.41, "end": 2408.51, "word": " ..", "probability": 0.48388671875}, {"start": 2408.51, "end": 2408.69, "word": " واحدة", "probability": 0.9650065104166666}, {"start": 2408.69, "end": 2408.99, "word": " خاصة", "probability": 0.9739583333333334}, {"start": 2408.99, "end": 2409.69, "word": " بالأم", "probability": 0.9640299479166666}, {"start": 2409.69, "end": 2409.73, "word": " ..", "probability": 0.79443359375}, {"start": 2409.73, "end": 2410.27, "word": " والتالتة", "probability": 0.92578125}, {"start": 2410.27, "end": 2410.61, "word": " فيما", "probability": 0.8251953125}, {"start": 2410.61, "end": 2410.87, "word": " بعد", "probability": 0.94775390625}, {"start": 2410.87, "end": 2411.43, "word": " اكتشفوا", "probability": 0.990234375}, {"start": 2411.43, "end": 2411.61, "word": " انها", "probability": 0.70458984375}, {"start": 2411.61, "end": 2411.91, "word": " عبارة", "probability": 0.9921875}, {"start": 2411.91, "end": 2412.07, "word": " عن", "probability": 0.99072265625}, {"start": 2412.07, "end": 2412.51, "word": " 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4587, 7578, 8978, 2423, 39184, 44615, 9122, 3215, 3224, 8032, 1863, 9778, 1211, 9381, 23758, 9673, 2407, 11242, 45367, 4032, 29538, 9673, 5016, 46958, 25720, 43242, 23758, 21542, 3215, 16472, 13412, 16606, 21984, 15844, 5551, 42213, 14739, 8717, 1211, 2655, 38436, 8978, 9673, 5016, 46958, 25720, 25062, 18513, 46007, 16472, 13412, 16606, 21984, 46811, 46811, 8978, 12602, 3615, 995, 10632, 21984], "avg_logprob": -0.18411726804123713, "compression_ratio": 1.784688995215311, "no_speech_prob": 7.3909759521484375e-06, "words": [{"start": 2414.36, "end": 2414.7, "word": "يعني", "probability": 0.924072265625}, {"start": 2414.7, "end": 2415.1, "word": " دليل", "probability": 0.95947265625}, {"start": 2415.1, "end": 2415.36, "word": " أن", "probability": 0.53857421875}, {"start": 2415.36, "end": 2416.54, "word": " الـ", "probability": 0.6357421875}, {"start": 2416.54, "end": 2417.12, "word": " metacondria", "probability": 0.577392578125}, {"start": 2417.12, "end": 2417.62, "word": " الموجودة", "probability": 0.9642333984375}, {"start": 2417.62, "end": 2417.72, "word": " في", "probability": 0.9560546875}, {"start": 2417.72, "end": 2417.84, "word": " الـ", "probability": 0.9013671875}, {"start": 2417.84, "end": 2418.12, "word": " spam", "probability": 0.583984375}, {"start": 2418.12, "end": 2418.7, "word": " قد", "probability": 0.980712890625}, {"start": 2418.7, "end": 2419.54, "word": " تتواجد", "probability": 0.9388671875}, {"start": 2419.54, "end": 2419.78, "word": " و", "probability": 0.332763671875}, {"start": 2419.78, "end": 2420.34, "word": " تضاعف", "probability": 0.8824462890625}, {"start": 2420.34, "end": 2420.46, "word": " و", "probability": 0.70068359375}, {"start": 2420.46, "end": 2420.76, "word": " تبقى", "probability": 0.983154296875}, {"start": 2420.76, "end": 2420.88, "word": " في", "probability": 0.9443359375}, {"start": 2420.88, "end": 2421.0, "word": " الـ", "probability": 0.59100341796875}, {"start": 2421.0, "end": 2421.32, "word": " imprint", "probability": 0.3662109375}, {"start": 2421.32, "end": 2423.28, "word": " كده", "probability": 0.7607421875}, {"start": 2423.28, "end": 2424.02, "word": " هنخلص", "probability": 0.9138671875}, {"start": 2424.02, "end": 2424.48, "word": " هذا", "probability": 0.83984375}, {"start": 2424.48, "end": 2425.28, "word": " الموضوع", "probability": 0.997802734375}, {"start": 2425.28, "end": 2425.4, "word": " و", "probability": 0.6650390625}, {"start": 2425.4, "end": 2425.6, "word": " هذه", "probability": 0.7958984375}, {"start": 2425.6, "end": 2426.26, "word": " المحاضرة", "probability": 0.9759521484375}, {"start": 2426.26, "end": 2426.54, "word": " عند", "probability": 0.81884765625}, {"start": 2426.54, "end": 2426.76, "word": " هذا", "probability": 0.90625}, {"start": 2426.76, "end": 2427.16, "word": " الحد", "probability": 0.986328125}, {"start": 2427.16, "end": 2427.36, "word": " ان", "probability": 0.59228515625}, {"start": 2427.36, "end": 2427.58, "word": " شاء", "probability": 0.976318359375}, {"start": 2427.58, "end": 2427.68, "word": " الله", "probability": 0.94580078125}, {"start": 2427.68, "end": 2427.86, "word": " على", "probability": 0.8916015625}, {"start": 2427.86, "end": 2428.2, "word": " أمل", "probability": 0.8134765625}, {"start": 2428.2, "end": 2428.84, "word": " أن", "probability": 0.634765625}, {"start": 2428.84, "end": 2429.28, "word": " نلتقي", "probability": 0.960693359375}, {"start": 2429.28, "end": 2429.48, "word": " في", "probability": 0.9541015625}, {"start": 2429.48, "end": 2430.04, "word": " المحاضرة", "probability": 0.9931640625}, {"start": 2430.04, "end": 2430.7, "word": " القادمة", "probability": 0.9938151041666666}, {"start": 2430.7, "end": 2431.12, "word": " ان", "probability": 0.537109375}, {"start": 2431.12, "end": 2431.5, "word": " شاء", "probability": 0.995361328125}, {"start": 2431.5, "end": 2432.0, "word": " الله", "probability": 0.95947265625}, {"start": 2432.0, "end": 2432.22, "word": " تم", "probability": 0.312255859375}, {"start": 2432.22, "end": 2432.5, "word": " تم", "probability": 0.72119140625}, {"start": 2432.5, "end": 2433.06, "word": " في", "probability": 0.89453125}, {"start": 2433.06, "end": 2433.54, "word": " رعاية", "probability": 0.9903564453125}, {"start": 2433.54, "end": 2433.78, "word": " الله", "probability": 0.62158203125}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2484.767375, "duration_after_vad": 2368.9899999999916}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/e8zUWOaK1rw_raw.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/e8zUWOaK1rw_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..0017ec1a544a2dbb7dd040fdff4872fb8f60a78a
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/e8zUWOaK1rw_raw.srt
@@ -0,0 +1,2308 @@
+1
+00:00:01,480 --> 00:00:05,680
+باسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,680 --> 00:00:11,460
+المسلين سيدنا محمد وعلى آله وصحبه أجمعين بداية
+
+3
+00:00:11,460 --> 00:00:16,740
+نرجو من الله الكريم أن تكونوا جميعا بخير استكمالا
+
+4
+00:00:16,740 --> 00:00:20,580
+لمبدأنا فيه من سلسلة محاضرات التلقيح الصناعي
+
+5
+00:00:20,580 --> 00:00:26,520
+أسبابه وسبوله وطرقه المتنوعة تحدثنا في الأسبوع
+
+6
+00:00:26,520 --> 00:00:35,040
+الماضي عن رحلة لسبيرنبداية من الـ cervic حتى وصولا
+
+7
+00:00:35,040 --> 00:00:37,860
+إلى ال fallopian tube من أجل حدوث عملية ال
+
+8
+00:00:37,860 --> 00:00:43,180
+fertilization وما يواجله من مخاطر ومعويقات هذه
+
+9
+00:00:43,180 --> 00:00:49,140
+المخاطر والمعويقات تلعب دورا أساسيا في انقاس عدد
+
+10
+00:00:49,140 --> 00:00:53,380
+ال sperm الذي قد يصل إلى البويضة وهذا أمر طبيعي
+
+11
+00:00:53,380 --> 00:00:58,160
+وامر محمود ولكن بشرط أن لا يزيد عن الأمر الطبيعي
+
+12
+00:00:59,840 --> 00:01:04,340
+سنستكمل اليوم بعض النقاط المتعلقة بالـ Transport
+
+13
+00:01:04,340 --> 00:01:09,260
+of Gametes and Fertilization وهو الجزء الثالث من
+
+14
+00:01:09,260 --> 00:01:12,260
+هذا الـ chapter والذي يتحدث عن آلية ال
+
+15
+00:01:12,260 --> 00:01:15,680
+fertilization كيف تحدث ال fertilization و أين تحدث
+
+16
+00:01:15,680 --> 00:01:19,740
+عملية ال fertilization وما المانع من إخصاب البويضة
+
+17
+00:01:19,740 --> 00:01:23,480
+بتوسبيرم وإن تم إخصاب البويضة بتوسبيرم ماذا سوف
+
+18
+00:01:23,480 --> 00:01:28,200
+يحدث هذه أمور سوف نتطرق إليها خلال محاضرة الأسبوع
+
+19
+00:01:28,200 --> 00:01:32,910
+الحالي إن شاء اللهبداية و قبل أن نبدأ بعملية ال
+
+20
+00:01:32,910 --> 00:01:36,750
+fertilization توقفنا فيما سبق عند الكوربوس
+
+21
+00:01:36,750 --> 00:01:41,610
+اليوتيوم و كيف ينتج هذا الجسم الأصفر و تحدثنا أن
+
+22
+00:01:41,610 --> 00:01:44,370
+الجسم الأصفر في البداية هو عبارة عن ال graphian
+
+23
+00:01:44,370 --> 00:01:50,770
+follicle بعد عملية ال ovulation تتحول
+
+24
+00:01:50,770 --> 00:01:57,290
+إلى كوربوس اليوتيوم بسبب بخ الدم بكمية كبيرة جدا
+
+25
+00:01:57,290 --> 00:02:02,220
+إلى هذه المنطقةوهذه المنطقة تلعب دورة مهمة في
+
+26
+00:02:02,220 --> 00:02:07,440
+إبقاء الحمل إن حدث من خلال إفراز بعض الهرمونات
+
+27
+00:02:07,440 --> 00:02:11,040
+فبالتالي Rapture Follicle بين جثين Giraffen
+
+28
+00:02:11,040 --> 00:02:15,340
+Follicle undergoes a series of strict changes that
+
+29
+00:02:15,340 --> 00:02:18,620
+are essentially for progression and of even
+
+30
+00:02:18,620 --> 00:02:23,500
+leading and supporting pregnancyيعني هذه التحولات
+
+31
+00:02:23,500 --> 00:02:26,400
+والتغيرات اللي بتصير على الجرفيا الفوليكي بعد
+
+32
+00:02:26,400 --> 00:02:30,460
+عملية ال ovulation تعتبر عاملًا حيويًا وعاملًا
+
+33
+00:02:30,460 --> 00:02:35,720
+أساسيًا في بقاء الحمل إن حدث و تدعيمه فبالتالي
+
+34
+00:02:35,720 --> 00:02:40,360
+وجودها ليس بالأمر الافتراضي الذي يحدث بشكل عشوائي
+
+35
+00:02:41,510 --> 00:02:44,630
+فماذا يحدث بعد عملية الـ ovulation؟ مباشرة بعد
+
+36
+00:02:44,630 --> 00:02:47,730
+عملية الإبادة الـ basement membrane الخاص بالـ
+
+37
+00:02:47,730 --> 00:02:52,190
+griffion follicle that's separated the granulosa
+
+38
+00:02:52,190 --> 00:02:56,330
+cell from the theca breakdown those allowing
+
+39
+00:02:56,330 --> 00:02:59,690
+thecal blood vessels to grow into the cavity of
+
+40
+00:02:59,690 --> 00:03:04,310
+the ruptured follicle يعني عملية الـ separation
+
+41
+00:03:04,310 --> 00:03:08,230
+اللي بتحدث ما بين الـ theca cell و ال granulosa
+
+42
+00:03:08,230 --> 00:03:12,180
+cell اللي موجودة في ال basement membraneللـ
+
+43
+00:03:12,180 --> 00:03:16,140
+Graafian Follicle تسمح بضخ كمية كبيرة جدا من الدم
+
+44
+00:03:16,140 --> 00:03:22,780
+في هذه المنطقة مما يسمح بتكوين الكوربوس اليوتر
+
+45
+00:03:22,780 --> 00:03:25,480
+فيما بعد و هذا بيقولك allowing thecal blood
+
+46
+00:03:25,480 --> 00:03:28,140
+vessels ال blood vessels الموجودة في الثيكل أنها
+
+47
+00:03:28,140 --> 00:03:33,030
+تنمو و تضخ كمية كبيرة جدا من الدمالمحمّد بالمواد
+
+48
+00:03:33,030 --> 00:03:36,650
+الغذائية في الـ cavity بعد عملية الـ rupture الـ
+
+49
+00:03:36,650 --> 00:03:39,710
+granulosa cell تعمل stimulation أو بيصيرلها
+
+50
+00:03:39,710 --> 00:03:43,030
+stimulation أو خلّيني أسميها بمعنى آخر بيصيرلها
+
+51
+00:03:43,030 --> 00:03:48,270
+variation و changing بفعل تلقائي مما يؤدي إلى
+
+52
+00:03:48,270 --> 00:03:52,170
+سلسلة من التغيرات هذه التغيرات تحدث في الشكل و في
+
+53
+00:03:52,170 --> 00:03:55,750
+الوظيفة نطلق على هذه التغيرات عملية بيسميها
+
+54
+00:03:55,750 --> 00:04:00,550
+لوتونيزيشن لذا اللوتونيزيشن هي a series or group
+
+55
+00:04:00,550 --> 00:04:06,100
+ofModification happened on granulosa cell لماذا
+
+56
+00:04:06,100 --> 00:04:11,040
+تحدث عن granulosa cell؟ لكي تخدم الوظيفة التي كانت
+
+57
+00:04:11,040 --> 00:04:15,540
+كوّنة لأجلها فيما بعد إذا اتحولت المكان إلى كورباس
+
+58
+00:04:15,540 --> 00:04:18,100
+اليوتيام أو الفولك الهادي اتحول إلى كورباس
+
+59
+00:04:18,100 --> 00:04:23,960
+اليوتيام وبقيت لتخدم الحمل خلال ما يقارب من 30 إلى
+
+60
+00:04:23,960 --> 00:04:30,060
+40 ساعة بعد ال ال H-waveبعد الـ high peak للـ LH
+
+61
+00:04:30,060 --> 00:04:33,740
+احسب تلاتين لاربعين ساعة this cell اللي سميتها
+
+62
+00:04:33,740 --> 00:04:38,620
+granulosa cell تسمى فيما بعد او تتحول فيما بعد إلى
+
+63
+00:04:38,620 --> 00:04:44,200
+خلايا اخرى تسمى granulosa utian cell اذا ال
+
+64
+00:04:44,200 --> 00:04:46,720
+granulosa cell بعد ما يصير عليها ال modification
+
+65
+00:04:46,720 --> 00:04:51,240
+اللي احنا حكينا عنه وسميناه lutealization بعد
+
+66
+00:04:51,240 --> 00:04:56,560
+اربعين ساعة من ال lutealizationأصبحت تسمى
+
+67
+00:04:56,560 --> 00:05:01,460
+Granulosa Lutein Cell وإلها وظيفة معينة Beginning
+
+68
+00:05:01,460 --> 00:05:06,060
+secreting increasing amount of progesterone along
+
+69
+00:05:06,060 --> 00:05:09,380
+with some estrogen إذن هذه الجرانيلوزا سيل اللي
+
+70
+00:05:09,380 --> 00:05:13,740
+اتحولت إلى Granulosa Lutein Cell أصبحت تلعب دورة
+
+71
+00:05:13,740 --> 00:05:19,400
+مهمة في إفراز كمية كبيرة وكافية من البروجسترون
+
+72
+00:05:19,400 --> 00:05:23,510
+بالإضافة إلى كمية من الاستروجينوالبروجيسترون عرفنا
+
+73
+00:05:23,510 --> 00:05:28,050
+في مصبق أنه همور مهم جدا يساعد على بقاء الحمل
+
+74
+00:05:28,050 --> 00:05:31,750
+وعملية ال implantation مهم جدا عملية ال
+
+75
+00:05:31,750 --> 00:05:36,250
+implantation لأن بدونها بصير عندي a portion in the
+
+76
+00:05:36,250 --> 00:05:39,810
+first trimester ولما نقول first trimester يعني أول
+
+77
+00:05:39,810 --> 00:05:45,010
+ثلاثة شهور من عملية الحمل ال granulosa اليوتيان
+
+78
+00:05:45,010 --> 00:05:49,530
+cell are terminally differentiated يعني بتصير
+
+79
+00:05:49,530 --> 00:05:52,320
+لعملية differentiatedتنتهي عملية الـ
+
+80
+00:05:52,320 --> 00:05:56,760
+differentiated وتبقى كما هي في مبتعد بمجرد
+
+81
+00:05:56,760 --> 00:06:01,880
+انقسامها يتوقف أو توقف عملية الانقسام تتوقف خلاص
+
+82
+00:06:01,880 --> 00:06:05,260
+بمجرد تحويل الـ granulosa cell إلى granulosa الـ
+
+83
+00:06:05,260 --> 00:06:08,440
+lutein cell مافي انقسام بعد كده مافي
+
+84
+00:06:08,440 --> 00:06:12,200
+differentiation توقفت جميع عمليات الانقسام وعمليات
+
+85
+00:06:12,200 --> 00:06:16,400
+التمييز المتعلقة بالـ granulosa cell بمجرد تحولها
+
+86
+00:06:16,400 --> 00:06:22,630
+إلى granulosa lutein cell بفعل lotalizationbut
+
+87
+00:06:22,630 --> 00:06:25,890
+they continued to secreted progesterone for 10
+
+88
+00:06:25,890 --> 00:06:29,350
+days طبعا مهمة جدا بيقولك صحيح ان اتحولت من
+
+89
+00:06:29,350 --> 00:06:33,510
+granulosa cell ل granulosa lutein cell واتوقفت من
+
+90
+00:06:33,510 --> 00:06:37,970
+انقسام واتوقفت من التمايز يعني هتبقى كما هي ولكنها
+
+91
+00:06:37,970 --> 00:06:41,790
+تبقى تلعب دورة مهمة في إفراز ال progesterone لمدة
+
+92
+00:06:41,790 --> 00:06:46,650
+عشر أيام او عشر أيام طب ليه؟ ببساطة جدا لإن خلال
+
+93
+00:06:46,650 --> 00:06:50,450
+فترة العشر أيام يجب أن تتكوّل بلسنتر
+
+94
+00:06:53,640 --> 00:06:58,320
+عفراز البروجيسترون منها وبالتالي يتوقف عفراز
+
+95
+00:06:58,320 --> 00:07:02,960
+البروجيسترون من الجرانيولوجيا اليوتيان سيت قدت
+
+96
+00:07:02,960 --> 00:07:06,400
+وظيفتها بعد عشر أيام خدوا بالك ليش بعد عشر أيام؟
+
+97
+00:07:06,400 --> 00:07:10,440
+لأن في فترة هذه يا إما بيصير pregnancy موجود وصار
+
+98
+00:07:10,440 --> 00:07:13,120
+له implantation يا إما مافيه عنده pregnancy
+
+99
+00:07:13,120 --> 00:07:18,740
+فبالتالي بيصير عنده menstrual cycle جديد The
+
+100
+00:07:18,740 --> 00:07:21,960
+secretion of human coronaginatotropin اللي بتسمي
+
+101
+00:07:21,960 --> 00:07:26,060
+HCGيلعب دورة مهمة في عملية الـ Maintenance of
+
+102
+00:07:26,060 --> 00:07:29,920
+Pregnancy until approximately the seventh week of
+
+103
+00:07:29,920 --> 00:07:35,100
+the pregnancy أو الـ gestation يعني بمعنى أخر أن
+
+104
+00:07:35,100 --> 00:07:39,560
+الهرمون اللي سميته HCG وهو اختصار له Human Chronic
+
+105
+00:07:39,560 --> 00:07:43,760
+Gonadotropin هذا مش هرمون عبث يفرز، لأ هرمون مهم
+
+106
+00:07:43,760 --> 00:07:50,060
+جدا يفرز بشكل مستمر ويلعب دورة أساسية ومهمة بجانب
+
+107
+00:07:50,060 --> 00:07:55,450
+البروجسترونفي المحافظة على الحمل وبقاءه لمدة ما
+
+108
+00:07:55,450 --> 00:08:00,770
+يقارب سبع أسابيع لمدة أول سبع أسابيع من الحمل ما
+
+109
+00:08:00,770 --> 00:08:04,010
+بين الأسبوع السابع للأسبوع العاشر من عملية الحمل
+
+110
+00:08:04,010 --> 00:08:08,230
+ال Corpus Luteum is replaced by the placenta in
+
+111
+00:08:08,230 --> 00:08:14,530
+term of progesterone production يعني بعد السبع
+
+112
+00:08:14,530 --> 00:08:19,290
+أسابيع وصولا للأسبوع العاشر البروجسترون يفقد
+
+113
+00:08:24,490 --> 00:08:29,330
+يعني الكوربوس اليوتياب تدريجيا يفقد قدرته على
+
+114
+00:08:29,330 --> 00:08:34,350
+إخراج وإفراز البروجسترون فمن سيحل محله؟ سيحل محله
+
+115
+00:08:34,350 --> 00:08:38,750
+الـ placental اللي بدأ تتكوّن هذه الفترة عملية
+
+116
+00:08:38,750 --> 00:08:41,110
+التحول وهذا الـ event اللي بتصير وهذا الطول اللي
+
+117
+00:08:41,110 --> 00:08:46,200
+بيصير هذه الفترة من عملية اليوتيابUteal Placenta
+
+118
+00:08:46,200 --> 00:08:50,420
+Shift ماهي المقصود فيها؟ بداية في أربع نقاط بسيطة
+
+119
+00:08:50,420 --> 00:08:54,300
+جدا جرانيلوزا سيل اتحولت إلى الجرانيلوزا اليوتيان
+
+120
+00:08:54,300 --> 00:09:00,460
+سيل قادر على إفراز البروجسترون وكمية من الاستروجين
+
+121
+00:09:00,460 --> 00:09:05,320
+البروجسترون مهم جدا في إبقاء الحمل و المساعدة على
+
+122
+00:09:05,320 --> 00:09:11,360
+الimplantationيبقى هذه العملية لمدة 7 أسابيع أول 7
+
+123
+00:09:11,360 --> 00:09:14,560
+أسابيع من عملية الحميدة ما بين السبوع السابع
+
+124
+00:09:14,560 --> 00:09:18,080
+والعشر تبدأ البلانسينتا في التكون لكي تأخذ مكان
+
+125
+00:09:18,080 --> 00:09:22,860
+الكوربوس اليوتيوم في إفراز البروجسترون بمجرد توقف
+
+126
+00:09:22,860 --> 00:09:27,340
+إفراز البروجسترون من الكوربوس اليوتيوم وإفرازه من
+
+127
+00:09:27,340 --> 00:09:31,760
+البلانسينتا هذه العملية بنسميها الـUtil Placental
+
+128
+00:09:31,760 --> 00:09:37,850
+Shift بمعنى آخر برجسترون as hormoneبدل ما يُفرَز
+
+129
+00:09:37,850 --> 00:09:40,850
+من الـ Luteal جرانيولوجيا الـ Luteal Cell أصبح
+
+130
+00:09:40,850 --> 00:09:45,230
+يُفرَز من الـ Placenta شيء كده يسموها Luteal الأصل
+
+131
+00:09:45,230 --> 00:09:50,690
+Placental الجديدة Shift من إلها In conception
+
+132
+00:09:50,690 --> 00:09:55,690
+cycle the life of the corpus luteum is extended
+
+133
+00:09:55,690 --> 00:09:58,570
+until the luteal placenta shift again يعني في
+
+134
+00:09:58,570 --> 00:10:02,230
+الوضع الطبيعي بقولك ال corpus luteum يبقى متوفر
+
+135
+00:10:02,230 --> 00:10:08,390
+يبقى فعال يبقى يعمل على إفراج البروجسترونحتى تكوّل
+
+136
+00:10:08,390 --> 00:10:11,790
+الـ placenta بمجرد تكوّل الـ placenta يتوقف عن
+
+137
+00:10:11,790 --> 00:10:17,370
+عملية الإفراز يعني بمعنى آخر وبشكل منطقي المفروض
+
+138
+00:10:17,370 --> 00:10:21,630
+يتوقف بشكل كامل عند الأسبوع العاشر ويبدأ بعد كده
+
+139
+00:10:21,630 --> 00:10:24,970
+في عملية ال degradation أو ال atrophy فده يعني
+
+140
+00:10:24,970 --> 00:10:29,410
+الكوربس اليوتيوم in the absence of fertilization
+
+141
+00:10:29,410 --> 00:10:33,410
+ماصارش فيه fertilization and hormone stimulus
+
+142
+00:10:33,410 --> 00:10:37,340
+provided by the early embryoالكوربس اليوتيام يبدأ
+
+143
+00:10:37,340 --> 00:10:41,440
+بالتخصيب للبوايضة والتخصيب للبوايضة والتخصيب
+
+144
+00:10:41,440 --> 00:10:46,260
+للبوايضة والتخصيب للبوايضة والتخصيب للبوايضة
+
+145
+00:10:46,260 --> 00:10:46,520
+والتخصيب للبوايضة والتخصيب للبوايضة والتخصيب
+
+146
+00:10:46,520 --> 00:10:48,260
+للبوايضة والتخصيب للبوايضة والتخصيب للبوايضة
+
+147
+00:10:48,260 --> 00:10:49,540
+والتخصيب للبوايضة والتخصيب للبوايضة والتخصيب
+
+148
+00:10:49,540 --> 00:10:54,900
+للبوايضة والتخصيب للبوايضة والتخصيب للبوايضة
+
+149
+00:10:54,900 --> 00:11:02,840
+والتخصيب للبوايضة والتخصيب للبوايضة والتخصيب
+
+150
+00:11:02,840 --> 00:11:12,290
+للبالنسبة للبروجيسترون ستكون تنقس
+
+151
+00:11:12,290 --> 00:11:16,790
+بشكل تدريجي او
+
+152
+00:11:16,790 --> 00:11:19,370
+تنقس او تدريجي او تدريجي او تدريجي او تدريجي او
+
+153
+00:11:19,370 --> 00:11:20,370
+تدريجي او تدريجي او تدريجي او تدريجي او تدريجي او
+
+154
+00:11:20,370 --> 00:11:21,710
+تدريجي او تدريجي او تدريجي او تدريجي او تدريجي او
+
+155
+00:11:21,710 --> 00:11:21,710
+تدريجي او تدريجي او تدريجي او تدريجي او تدريجي او
+
+156
+00:11:21,710 --> 00:11:23,790
+تدريجي او تدريجي او تدريجي او تدريجي او تدريجي او
+
+157
+00:11:23,790 --> 00:11:30,550
+تدريجي او تدريجي او تدريجي او تلأنه مافي بلسنت
+
+158
+00:11:30,550 --> 00:11:35,390
+أتكونت فبالتالي بعد 8 أسابيع أو 10 أسابيع مالوش
+
+159
+00:11:35,390 --> 00:11:38,970
+function فبصير له لوتوليزي اللي أنا حكيتها قبل
+
+160
+00:11:38,970 --> 00:11:43,030
+بشوية أو الـdegeneration طيب، this is necessary to
+
+161
+00:11:43,030 --> 00:11:45,510
+allow the development of a new follicle providing
+
+162
+00:11:45,510 --> 00:11:49,810
+a new chance for fertilization بمجرد أنه يبدأ
+
+163
+00:11:49,810 --> 00:11:53,590
+الكوربسليوتن في ال degradation أو ال breakdown هذا
+
+164
+00:11:53,590 --> 00:11:57,720
+بيعطي إشارة مباشرة إلى الhybrophilomasبعد ذلك إلى
+
+165
+00:11:57,720 --> 00:11:59,960
+الـ anterior loop of the pituitary gland عشان تبدأ
+
+166
+00:11:59,960 --> 00:12:04,660
+دورة جديدة من إفراز ال FSH والLH عشان يعطيني دورة
+
+167
+00:12:04,660 --> 00:12:09,140
+شهرية جديدة وعملية إبادة جديدة جديدة مما يسمح
+
+168
+00:12:09,140 --> 00:12:15,280
+بحدود الحمل مستقبلاً and it's okay by the 22 to 24
+
+169
+00:12:15,280 --> 00:12:19,140
+of menstrual cycle يعني بمعنى أخر أن هذه العملية و
+
+170
+00:12:19,140 --> 00:12:25,100
+هذه ال atrophy تبدأ بتصيرفي اليوم 22 لليوم 24 من
+
+171
+00:12:25,100 --> 00:12:29,520
+الدورة عشان تبدأ دورة جديدة تماشي ماتبيحدث إذا
+
+172
+00:12:29,520 --> 00:12:32,760
+ماصارش fertilization يعني there is no pregnancy
+
+173
+00:12:32,760 --> 00:12:36,300
+خدوا
+
+174
+00:12:36,300 --> 00:12:40,360
+بالكوا من الكلام مافي مشكلة بعد سبع أسابيع بيصيروا
+
+175
+00:12:40,360 --> 00:12:44,320
+أثروا فيه بعد سبع أسابيع هو فبتوقف خليني أسميه إذا
+
+176
+00:12:44,320 --> 00:12:47,680
+جاز التعبير لإنه لبدأ سنة أخدت الكمل أكبر
+
+177
+00:12:50,310 --> 00:12:54,050
+خلاص فصار له reduction في ال functional limit هذا
+
+178
+00:12:54,050 --> 00:12:58,540
+يعني الكوربوس اليتيحولكن لو ماصارش حمل مافيش داعي
+
+179
+00:12:58,540 --> 00:13:03,840
+إنه يستمر في إنتاج البروجسترون عشان كده بتوقف و
+
+180
+00:13:03,840 --> 00:13:06,900
+ببدأ يدخل فيه الـdegeneration في اليوم ال 22 من
+
+181
+00:13:06,900 --> 00:13:10,400
+الدورة إذا المعلومة الأولى مافيها تعارض في
+
+182
+00:13:10,400 --> 00:13:13,560
+المعلومة التانية المعلومة الأولى تتعلق إذا صار
+
+183
+00:13:13,560 --> 00:13:16,720
+pregnancy المعلومة التانية إذا ماصارش pregnancy
+
+184
+00:13:16,720 --> 00:13:21,100
+تمام؟ تمام ال second phase the functional
+
+185
+00:13:33,860 --> 00:13:37,460
+مهم جدًا بعد ما يصيره الـ Degeneration و يصير
+
+186
+00:13:37,460 --> 00:13:39,420
+Reduction عفويا، بعد ما يصير Reduction في
+
+187
+00:13:39,420 --> 00:13:42,640
+البروجسترون و يبدأ يصير له Lutealization و
+
+188
+00:13:42,640 --> 00:13:46,420
+Degeneration لازم يصير Removing للقربس اليوتيام
+
+189
+00:13:46,420 --> 00:13:49,920
+بشكل كامل علشان ما يصيرش Accumulation لأنه كده
+
+190
+00:13:49,920 --> 00:13:54,280
+بالك كل دورةبيصير عندك Corpus Luteum Formation لأن
+
+191
+00:13:54,280 --> 00:13:58,340
+أصد الـ Corpus Luteum هو عبارة عن Graphene
+
+192
+00:13:58,340 --> 00:14:01,420
+Follicle اللي بتطلع منها البويضة إذا كل عملية
+
+193
+00:14:01,420 --> 00:14:05,000
+إبادة وخروج بويضة في عندك Graphene Follicle تتحول
+
+194
+00:14:05,000 --> 00:14:09,160
+إلى Corpus Luteum تصور على مدار السنة في عندك مثلا
+
+195
+00:14:09,160 --> 00:14:15,150
+على أقل تقليد 12عملية لبعضة، يعني إتناشر فوريكل،
+
+196
+00:14:15,150 --> 00:14:17,650
+يعني إتناشر كوربا سليوتين إذا صار accumulation
+
+197
+00:14:17,650 --> 00:14:23,230
+لهذه الأنسجة مع بعض لبعض تؤدي إلى حدوث مشكلة في ال
+
+198
+00:14:23,230 --> 00:14:27,490
+over it إحنا ك human في غين عنها، إحنا ك human في
+
+199
+00:14:27,490 --> 00:14:30,630
+غين عنها فبالتالي لازم يصير ال degeneration و
+
+200
+00:14:30,630 --> 00:14:36,970
+removing لكوربا سليوتين بشكل كاملremoving الكوربا
+
+201
+00:14:36,970 --> 00:14:42,110
+سليوتيام بشكل ثوري ولكن بياخد فترة زمانية طويلة
+
+202
+00:14:42,110 --> 00:14:45,450
+إلى حد ما مش طويلة يعني سنين لأ طويلة إلى حد ما
+
+203
+00:14:45,450 --> 00:14:48,710
+مقصود بالcycle مش بعد كل cycle بروح وبنتي بده
+
+204
+00:14:48,710 --> 00:14:51,730
+اتنين اتلات اربع cycle عشان ينتهي الاول كوربا
+
+205
+00:14:51,730 --> 00:14:55,210
+سليوتيام عشان كده بحكيلي انه ال structure
+
+206
+00:14:55,210 --> 00:14:58,230
+lutealized and its beginning after the degrees of
+
+207
+00:14:58,230 --> 00:15:01,810
+progesterone as we said secretion also complete
+
+208
+00:15:01,810 --> 00:15:04,750
+deletion of the كوربا سليوتيامshould be take
+
+209
+00:15:04,750 --> 00:15:08,370
+several cycle يعني ممكن بعد 20 cycle كوربس
+
+210
+00:15:08,370 --> 00:15:12,250
+اليوتيام يختفي الأول اللي اتكون هذه الفكرة المقصود
+
+211
+00:15:12,250 --> 00:15:17,250
+فيها يعني بمعنى أخر مش انتهاء الدورة ومافي عملية
+
+212
+00:15:17,250 --> 00:15:20,770
+pregnancy ينتهي الكوربس اليوتيام بشكل فوري لأ
+
+213
+00:15:20,770 --> 00:15:24,090
+بياخد several cycle ممكن تكون خمسة، ستة، سبعة،
+
+214
+00:15:24,090 --> 00:15:29,590
+عشر، بيننا على طبيعة السيدةDuring the regeneration
+
+215
+00:15:29,590 --> 00:15:32,830
+of the corpus luteum, the granulosa luteum cell
+
+216
+00:15:32,830 --> 00:15:37,810
+degenerate and are replaced with collagenous scar
+
+217
+00:15:37,810 --> 00:15:40,770
+tissue خلال عملية الـdegeneration و الـlysis،
+
+218
+00:15:40,770 --> 00:15:44,150
+الجرانولوزا السل تتحول وتستبدل وتكسى
+
+219
+00:15:44,150 --> 00:15:48,110
+بالـcollagenous tissue لونها أبيض، عشان كده
+
+220
+00:15:48,110 --> 00:15:50,850
+الـcorpus luteum بتتحول من corpus luteum with
+
+221
+00:15:50,850 --> 00:15:55,050
+yellow color إلى corpus albicum with white color،
+
+222
+00:15:55,050 --> 00:15:59,300
+لأنه عبارة عن أليافكل جيل والكل جيل دائما أبيض
+
+223
+00:15:59,300 --> 00:16:03,720
+اللون لذلك كوربس اليوتيام في حالة شيخوخته خلّيني
+
+224
+00:16:03,720 --> 00:16:08,540
+أسميه أو توجهه إلى الـdegeneration phase بتحول من
+
+225
+00:16:08,540 --> 00:16:11,780
+اللون الأصفر إلى اللون الأبيض بسميه كوربس اليوتيام
+
+226
+00:16:11,780 --> 00:16:21,780
+2 كوربس البكند ده السؤال المهم جدافهمنا كيف تحدث
+
+227
+00:16:21,780 --> 00:16:25,580
+الـ ovulation فهمنا كيف تتحول الجريفيا الفوليكية
+
+228
+00:16:25,580 --> 00:16:29,120
+إلى كوربس اليوتيام فهمنا متى يختفي الكوربس
+
+229
+00:16:29,120 --> 00:16:33,760
+اليوتيام سواء كان في ال case pregnant أو non
+
+230
+00:16:33,760 --> 00:16:37,320
+-pregnant شو بيحصل في ال fertilization؟ وشو هي ال
+
+231
+00:16:37,320 --> 00:16:40,500
+fertilization؟ و أين بتحصل ال fertilization؟ ال
+
+232
+00:16:40,500 --> 00:16:44,120
+fertilization ببساطة جدا هي عملية تحدث عند القيقاء
+
+233
+00:16:44,120 --> 00:16:50,830
+الجميطات process should be occur when جميطface to
+
+234
+00:16:50,830 --> 00:16:54,370
+face يعني الجميع بتبقى face to face علشان يصير في
+
+235
+00:16:54,370 --> 00:16:57,990
+coupling ما بينهم أو joint ما بينهم إيش يعني
+
+236
+00:16:57,990 --> 00:17:00,510
+coupling و إيش يعني joint؟ مش coupling بالشكل
+
+237
+00:17:00,510 --> 00:17:04,030
+المتعارف أو الشكل المتوقع ولكن هي عبارة عن
+
+238
+00:17:04,030 --> 00:17:07,310
+penetration لل spear ال oocyte يحدث لها
+
+239
+00:17:07,310 --> 00:17:11,970
+penetration بواصل spear only one single spear أي
+
+240
+00:17:11,970 --> 00:17:15,130
+بويضة تخصّف ب two spear إن حدث بيصيرها
+
+241
+00:17:15,130 --> 00:17:18,330
+degeneration مباشرة إن حدث بيصيرها degeneration
+
+242
+00:17:18,330 --> 00:17:22,620
+مباشرةإتفقنا؟ إتفقنا When spermatozoa started to
+
+243
+00:17:22,620 --> 00:17:26,300
+penetrate the coronary dieta that surrounding the
+
+244
+00:17:26,300 --> 00:17:32,000
+egg and end with the invasion of the maternal and
+
+245
+00:17:32,000 --> 00:17:35,580
+paternal chromosomes after spermatozoa has entered
+
+246
+00:17:35,580 --> 00:17:38,860
+the egg يعني هي عبارة عن عملية تبدأ باقتراط ال
+
+247
+00:17:38,860 --> 00:17:42,420
+sperm ال male gametes من ال female gametes ال
+
+248
+00:17:42,420 --> 00:17:45,930
+Oocyteيبدأ الـ sperm باختراق الـ corona radiata
+
+249
+00:17:45,930 --> 00:17:51,450
+السلسة المحيطة فيها ثم الـ zona pellucida ثم تندمج
+
+250
+00:17:51,450 --> 00:17:54,210
+المادة الوراثية الخاصة بالـ maternal بالمادة
+
+251
+00:17:54,210 --> 00:17:58,110
+الوراثية الخاصة بالـ maternal اندماجا كاملا من
+
+252
+00:17:58,110 --> 00:18:02,990
+حصول نواة واحدة هنا بسميها fertilized oocyte
+
+253
+00:18:02,990 --> 00:18:08,550
+fertilized oocyte يعني بويضة مخصمة ال corona
+
+254
+00:18:08,550 --> 00:18:12,790
+radiata هي عبارة عن خلايا تحيط بالـ oocytewith a
+
+255
+00:18:12,790 --> 00:18:16,410
+high cellular layer with an intracellular matrix
+
+256
+00:18:16,410 --> 00:18:19,370
+consist of يعني هي عبارة عن خلايا محيطة بالـ
+
+257
+00:18:19,370 --> 00:18:22,170
+Oocyte من الخارج ولكن ال matrix في الداخل التابع
+
+258
+00:18:22,170 --> 00:18:29,450
+الخاص فيها يحتوي على مواد أخرىالبروتينز بشكل أساسي
+
+259
+00:18:29,450 --> 00:18:33,990
+ال high concentration of carbohydrate and
+
+260
+00:18:33,990 --> 00:18:37,610
+hyaluronic acid خدوا بالك المواد هذه مهمة جدا لازم
+
+261
+00:18:37,610 --> 00:18:41,450
+تكون فيها لأنها بتغذ البويضة بشكل أساسي في المراحل
+
+262
+00:18:41,450 --> 00:18:45,850
+الأولى من عملية ال maturation it is why believed
+
+263
+00:18:45,850 --> 00:18:51,910
+that hyaluronidase present
+
+264
+00:18:51,910 --> 00:18:56,050
+or released from the head of a sperm play a very
+
+265
+00:18:56,050 --> 00:19:00,390
+important roleوبين تريدت كورونا ردياتا طالما أن
+
+266
+00:19:00,390 --> 00:19:03,490
+كورونا ردياتا هذه الخلية فيها مراكب اسمه الهيارونك
+
+267
+00:19:03,490 --> 00:19:08,470
+أسد طبيعي ومنطقي يجب أن يكون في ال sperm head
+
+268
+00:19:08,470 --> 00:19:12,390
+إنزين يكسر هذه المكونة لماذا هذه المكونة موجودة؟
+
+269
+00:19:12,390 --> 00:19:15,870
+أو لماذا هذه المادة موجودة؟ الهيارونك أسد الموجود
+
+270
+00:19:15,870 --> 00:19:19,210
+في كورونا ردياتا بحافظ على تماسك الخلايا حول
+
+271
+00:19:19,210 --> 00:19:23,210
+البويضة عشان ال sperm يخترق هذا التماسك البنيان
+
+272
+00:19:23,210 --> 00:19:27,610
+المرسوسحول البوايدة لازم يعمل تكسير في هذا البنيان
+
+273
+00:19:27,610 --> 00:19:31,830
+أو تكسير في المادة الموجودة فبيفرز الـ heto-sperm
+
+274
+00:19:31,830 --> 00:19:37,050
+بيحتوي على vesicles تفرز انزيم بيشتغل ضد الـ
+
+275
+00:19:37,050 --> 00:19:41,050
+hyaluronic acid اسمه hyaluronidase enzyme بيعمل
+
+276
+00:19:41,050 --> 00:19:46,070
+breakdown for this complex فبيساعد الـ sperm على
+
+277
+00:19:46,070 --> 00:19:51,800
+اختراق البوايدةمن خلال اختراق الكورونا رادياتا but
+
+278
+00:19:51,800 --> 00:19:55,000
+the active swimming movement of the sperm are also
+
+279
+00:19:55,000 --> 00:19:58,860
+important هل يعني ان ال sperm يستطيع اختراق
+
+280
+00:19:58,860 --> 00:20:04,360
+البويضة من خلال افراز المادة اللي سمتها هيرونيد من
+
+281
+00:20:04,360 --> 00:20:09,760
+خلال افراز المادة التي تعمل على الهيرونك أسد؟ لأ
+
+282
+00:20:09,760 --> 00:20:13,400
+صح هي بتلعب دور أساسي ولكن لازم plus ال movement
+
+283
+00:20:13,400 --> 00:20:17,400
+وحنشوفها كمان شوية تحت انوار ال activation ال
+
+284
+00:20:17,400 --> 00:20:21,020
+movement حنشوفهابشرحها و نسمعها و نشوفها في فيديو
+
+285
+00:20:21,020 --> 00:20:24,340
+ان شاء الله اذا عملية ال penetration تعتمد على
+
+286
+00:20:24,340 --> 00:20:28,180
+نقطتين أساسيتين افراز انزيم يعمل على الهيارونك أسد
+
+287
+00:20:28,180 --> 00:20:34,640
+الهيارونك أسد بيشتغل عليه و ال movement اللي تحدث
+
+288
+00:20:34,640 --> 00:20:37,480
+في ال sperm من خلال ال swimming من خلال ال
+
+289
+00:20:37,480 --> 00:20:45,420
+swimming اخترق ال sperm ال corona radiata بعد كده
+
+290
+00:20:45,420 --> 00:20:50,890
+لازم يواجهالحائط الآخر أو المانع الآخر جاء من و
+
+291
+00:20:50,890 --> 00:20:54,710
+يصل للمادة الوراثية اللي خاصة بالبويضة وهذا المانع
+
+292
+00:20:54,710 --> 00:21:00,490
+يسمى ZD وهو عبارة عن زونافليوسيدا، so the sperm
+
+293
+00:21:00,490 --> 00:21:04,090
+should be penetrated the zoonapelucida after
+
+294
+00:21:04,090 --> 00:21:07,660
+attachment with the receptorThe Outer Surface of
+
+295
+00:21:07,660 --> 00:21:12,100
+Zoonopathy وفي رسبتور على الـ Oocyte أكيد في
+
+296
+00:21:12,100 --> 00:21:14,860
+رسبتور و لا كيف بتصير فيه أنه عندي نوع من أنواع
+
+297
+00:21:14,860 --> 00:21:19,080
+التخصصية أو الخصوصية ال specificity كيف بتصير و
+
+298
+00:21:19,080 --> 00:21:25,520
+إلا ممكن أحطن بوايض ال human مثلا بوايض الطائر نطف
+
+299
+00:21:25,520 --> 00:21:29,020
+تعتبط خاصة بطائر معين أو بحيوان معين و هذا شيء غير
+
+300
+00:21:29,020 --> 00:21:33,960
+منطقي فبالتالي في رسبتور مهم جدا علشان يصير في
+
+301
+00:21:33,960 --> 00:21:37,730
+عنديattachment ثم penetration ثم fertilization
+
+302
+00:21:37,730 --> 00:21:44,430
+زوناف اليوسيدا ثقنسها يقدر بحوالي 13 ميكромتر تبعد
+
+303
+00:21:44,430 --> 00:21:49,650
+خاصة بـ human female oocyte تتكوّر من جليكو بروتين
+
+304
+00:21:49,650 --> 00:21:55,670
+بشكل أساسي تقسم إلى زوناف اليوسيدا 1,2,3,4 جمعها
+
+305
+00:21:55,670 --> 00:21:59,930
+مع بعضها لتصميم جزء أساسي من الـ polymerized into
+
+306
+00:21:59,930 --> 00:22:03,720
+long filamentيعني هذه ترتبط مع بعضها البعض عشان
+
+307
+00:22:03,720 --> 00:22:07,900
+تديني الـ Zoonopelucida الكاملة المتعرف عليها طبعا
+
+308
+00:22:07,900 --> 00:22:11,820
+بعد ما يصير اختراق للـ corona radiata بفعل الـ
+
+309
+00:22:11,820 --> 00:22:16,100
+sperm الـ sperm مباشرة بعمل search على الـ
+
+310
+00:22:16,100 --> 00:22:22,200
+receptor و بتتصل مع الـ Zoonopelucida من خلال الـ
+
+311
+00:22:22,200 --> 00:22:25,860
+receptor الـ Zoonopelucida by mean of the plasma
+
+312
+00:22:25,860 --> 00:22:29,830
+membrane of the sperm headSpermatozoa binds
+
+313
+00:22:29,830 --> 00:22:34,170
+specifically to the silica acid molecule that is
+
+314
+00:22:34,170 --> 00:22:37,170
+attached with the polypeptide core of the
+
+315
+00:22:37,170 --> 00:22:41,130
+zoonopelucida molecule بمعنى آخر أنه عشان يصير
+
+316
+00:22:41,130 --> 00:22:45,230
+penetration للـOocyte أو للـZoonopelucida لازم ال
+
+317
+00:22:45,230 --> 00:22:50,870
+sperm ينسك في منطقة معينةلا تتواجد إلا في الـ
+
+318
+00:22:50,870 --> 00:22:55,250
+zoonabulucida 3 تسمى الـ silica acid molecule يعني
+
+319
+00:22:55,250 --> 00:23:01,490
+كأن الـ sperm متخصص بالارتباط بالـ silica acid
+
+320
+00:23:01,490 --> 00:23:09,270
+molecule الموجود في zoonabulucida 3 والذي مرتبط
+
+321
+00:23:09,270 --> 00:23:11,570
+بالـ polypeptide core of zoonabulucida 3 بشكل
+
+322
+00:23:11,570 --> 00:23:16,180
+أساسيبشكل أساسي موجودة في أو مرتبط بهذا الـ Silic
+
+323
+00:23:16,180 --> 00:23:20,480
+Acid في الـ Poly-Tied Core of Zoonopelucid-3
+
+324
+00:23:20,480 --> 00:23:24,520
+ميكيول on the surface of sperm head are specific
+
+325
+00:23:24,520 --> 00:23:28,160
+binding site of Zoonopelucid-3 sperm receptor on
+
+326
+00:23:28,160 --> 00:23:31,640
+the Zoonopelucid So what is the meaning of this
+
+327
+00:23:31,640 --> 00:23:38,530
+paragraph؟ ببساطة إن الـ spermبيبحث عن منطقة في
+
+328
+00:23:38,530 --> 00:23:41,910
+الـ Zoonabolista 3 فقط لغير هي عبارة عن الـ
+
+329
+00:23:41,910 --> 00:23:45,930
+Receptor لأنها تحتوي على مادة يختص فيها ولا يتعرف
+
+330
+00:23:45,930 --> 00:23:49,870
+إلا عليها لـ sperm مثلا تسمى Silic Acid، هذا الـ
+
+331
+00:23:49,870 --> 00:23:52,890
+Silic Acid الـ attachment و الـ polypeptide core
+
+332
+00:23:52,890 --> 00:23:56,100
+الموجود في الـ Zoonabolistaيعني تشتغل هذه المنطقة
+
+333
+00:23:56,100 --> 00:24:01,220
+كـ Receptor وهي موجودة هيرقبط فيها ب sperm تمهيدة
+
+334
+00:24:01,220 --> 00:24:06,540
+لعملية إفراز الإنزيمات الهاضمة للـ Zona Pellucida
+
+335
+00:24:06,540 --> 00:24:11,840
+طيب، before binding to the Zona Pellucida ممانيا
+
+336
+00:24:11,840 --> 00:24:15,100
+الـ spermatozoa undergo to a chromosomal reaction
+
+337
+00:24:15,100 --> 00:24:21,250
+طبعا جابلما يتم الإرتباط و قبل ما يصل إلى الـ
+
+338
+00:24:21,250 --> 00:24:24,650
+receptor و يصير فيه إرتباط بشكل واضح و قوي لازم
+
+339
+00:24:24,650 --> 00:24:28,830
+يصير عند الـ sperm full active و لشأن يصير الـ
+
+340
+00:24:28,830 --> 00:24:33,530
+sperm full active يعني لازم يكون قادر على إفراز
+
+341
+00:24:33,530 --> 00:24:38,740
+الإنزيمات المقلوبة تحت مصطلحأكروزومال reaction تب
+
+342
+00:24:38,740 --> 00:24:41,160
+شو بيصير في الـ acrosomal reaction؟ وشو هو الـ
+
+343
+00:24:41,160 --> 00:24:43,840
+acrosomal reaction؟ الـ acrosomal reaction سلسلة
+
+344
+00:24:43,840 --> 00:24:47,020
+من التفاعلات بتصير على الـ acrosome الموجود في
+
+345
+00:24:47,020 --> 00:24:51,800
+مقدمة الـ head للـ sperm تمهيدا لإفراز محتويات الـ
+
+346
+00:24:51,800 --> 00:24:56,120
+physical التي تحتوي على الإنزيمات الغاضبة كيف
+
+347
+00:24:56,120 --> 00:25:00,780
+تبدأ؟ في البدايةفي بداية تطور الـ acrosome
+
+348
+00:25:00,780 --> 00:25:04,740
+reaction بيصير في عندي حاجة بيسموها massive influx
+
+349
+00:25:04,740 --> 00:25:07,100
+of calcium شو يعني massive؟ يعني without ATP
+
+350
+00:25:07,100 --> 00:25:11,620
+influx خروج، تدفق يعني كأنه الكالسيوم الموجود في
+
+351
+00:25:11,620 --> 00:25:14,360
+الـ head of the sperm أو الموجود في الـ acrosome
+
+352
+00:25:14,360 --> 00:25:22,280
+يخرج نحو الخارج بشكل تلقائي CA plus 2 through the
+
+353
+00:25:22,280 --> 00:25:26,410
+plasma membrane of the sperm headهذا البروسيز اللي
+
+354
+00:25:26,410 --> 00:25:30,570
+مقصود فيها influx أو influx كبير من الكالسيوم من
+
+355
+00:25:30,570 --> 00:25:36,630
+جهة إسبانيا يكون مصاحبه مباشرة influx للسوديوم و
+
+356
+00:25:36,630 --> 00:25:40,690
+efflux للهيدروجين يعني كأنه مجرد ما يبدأ ال
+
+357
+00:25:40,690 --> 00:25:47,180
+reaction الكالسيوم هيطلع من جهة إسبانياهيطلع معه
+
+358
+00:25:47,180 --> 00:25:51,760
+السوديوم بينما الهيدروجين هيدخل داخل الـ head of
+
+359
+00:25:51,760 --> 00:25:57,560
+spirit الخروج والتدفق influx والدخول efflux هذا
+
+360
+00:25:57,560 --> 00:26:01,600
+بيعمل increasing للـ intracellular pH this process
+
+361
+00:26:01,600 --> 00:26:06,780
+caused exocytosis of the acrosomal vesicle هذه
+
+362
+00:26:06,780 --> 00:26:09,580
+مهمة جدا، خروج الكالسوم، خروج السوديومودخول
+
+363
+00:26:09,580 --> 00:26:13,040
+الهيدروجين بيعمل زيادة في الـ intracellular بيقرش
+
+364
+00:26:13,040 --> 00:26:17,500
+الخاصة بالـ sperm مما يسمح ويسبب عيب نسميه
+
+365
+00:26:17,500 --> 00:26:22,360
+Exocytosis Exocytosis of acrosome vesicles يعني
+
+366
+00:26:22,360 --> 00:26:25,440
+خروج الـ acrosome في الـ vesicles تخدوا بالك اندو
+
+367
+00:26:25,440 --> 00:26:30,240
+تختلف عن إجزو اندو للداخل إجزو للخارج لأنه لازم
+
+368
+00:26:30,240 --> 00:26:33,900
+تطلع هذه الـ vesicles عشان تفرز محتوى عشان تدمر
+
+369
+00:26:33,900 --> 00:26:41,050
+الحواجز التي تمناها من الوصول إلى الواحدةطبعاً هذا
+
+370
+00:26:41,050 --> 00:26:49,870
+الوضع في إطلاق مجموعة من الانزينات اللاتك انزينات
+
+371
+00:26:49,870 --> 00:26:51,290
+اللاتك انزينات اللاتك انزينات اللاتك انزينات
+
+372
+00:26:51,290 --> 00:26:51,870
+اللاتك انزينات اللاتك انزينات اللاتك انزينات
+
+373
+00:26:51,870 --> 00:26:53,050
+اللاتك انزينات اللاتك انزينات اللاتك انزينات
+
+374
+00:26:53,050 --> 00:26:53,510
+اللاتك انزينات اللاتك انزينات اللاتك انزينات
+
+375
+00:26:53,510 --> 00:26:53,510
+اللاتك انزينات اللاتك انزينات اللاتك انزينات
+
+376
+00:26:53,510 --> 00:26:54,510
+اللاتك انزينات اللاتك انزينات اللاتك انزينات
+
+377
+00:26:54,510 --> 00:26:54,850
+اللاتك انزينات اللاتك انزينات اللاتك انزينات
+
+378
+00:26:54,850 --> 00:26:57,750
+اللاتك انزينات اللاتك انزينات اللاتك انزينات
+
+379
+00:26:57,750 --> 00:27:07,770
+اللاتك انزينات اللاتك انزينات اللاتك انزينات
+
+380
+00:27:07,770 --> 00:27:12,820
+اللاتوإفراز محتويات الـ acrosome اللي بنسميها
+
+381
+00:27:12,820 --> 00:27:16,280
+lithic enzyme أو degenerate enzyme أو licensed
+
+382
+00:27:16,280 --> 00:27:20,840
+enzyme يعني الانزيمات الغاضمة بشكل أساسي فبالتالي
+
+383
+00:27:20,840 --> 00:27:25,960
+مهم جدا أن تصير هذه العمليات علشان تبدأ ويبدأ ال
+
+384
+00:27:25,960 --> 00:27:30,880
+acrosome أن يفرز محتوى ماهي محتوياته؟ licensed
+
+385
+00:27:30,880 --> 00:27:34,240
+enzyme أو lithic enzyme penetration of the zona
+
+386
+00:27:34,240 --> 00:27:41,230
+pellucida بتصير بطريقتينالطريقة الأولى هي
+
+387
+00:27:41,230 --> 00:27:44,470
+إفراز الإنزيمات الطريقة التانية هي عبارة عن الـ
+
+388
+00:27:44,470 --> 00:27:47,090
+high active motility للـ sperm اللي بنسميها
+
+389
+00:27:47,090 --> 00:27:50,270
+hyperactivation .. hyperactivation .. هنشوفها و
+
+390
+00:27:50,270 --> 00:27:54,810
+اتكلمنا عنها المحاضرة السابقة أشهر الإنزيمات التي
+
+391
+00:27:54,810 --> 00:28:00,150
+تُفرَز خلال عملية الـ acrosome reaction هو إنزين
+
+392
+00:28:00,150 --> 00:28:04,760
+بنسميه الـ acrosinالـ Acrosin هو عبارة عن a serine
+
+393
+00:28:04,760 --> 00:28:08,440
+proteinase that is formed to the inner acrosome
+
+394
+00:28:08,440 --> 00:28:11,540
+membrane هو عبارة عن البروتينيز، عشان كده بسميه
+
+395
+00:28:11,540 --> 00:28:15,180
+Acrosin هو بروتينيز انزيم يحتوى على الـ Serine
+
+396
+00:28:15,180 --> 00:28:19,140
+موجود في الـ Acrosome membrane ومهم جدا في عملية
+
+397
+00:28:19,140 --> 00:28:22,140
+.. مرتبط في inner surface of Acrosome membrane
+
+398
+00:28:22,140 --> 00:28:26,520
+ومهم جدا في عملية ال penetration الـ Acrosin هل له
+
+399
+00:28:26,520 --> 00:28:31,040
+معلومات أخرى، تعريف آخر، مواصفات أخرى؟ بهمنيبرو
+
+400
+00:28:31,040 --> 00:28:36,320
+أكروزين عبارة عن endoprotease enzyme هو عبارة عن
+
+401
+00:28:36,320 --> 00:28:39,580
+endoprotease enzyme with terpsin-like for example
+
+402
+00:28:39,580 --> 00:28:44,420
+بيكون localized في الـ acrosome reaction الـ
+
+403
+00:28:44,420 --> 00:28:47,380
+enzymatic بيكون الـ activity تبعته بيكون inactive
+
+404
+00:28:47,380 --> 00:28:50,940
+طالما هو داخل الـ acrosome بيكون inactive على شكل
+
+405
+00:28:50,940 --> 00:28:57,260
+زيموجين برو أكروزين بمجرد ما يتحول ويتنشط بتتحول
+
+406
+00:28:57,260 --> 00:29:00,710
+من البرو أكروزين in active formأو زي الموجود in
+
+407
+00:29:00,710 --> 00:29:06,650
+active form إلى أكروزين في ال active form أو بيبدأ
+
+408
+00:29:06,650 --> 00:29:09,930
+ال action تبعه مهم جدا يكون داخل ال physical
+
+409
+00:29:09,930 --> 00:29:12,970
+الخاصة بالchromosome inactive علشان ما يعمل side
+
+410
+00:29:12,970 --> 00:29:19,470
+effect خلال عمل و تطور ال spirit هذه فكرة أو طريقة
+
+411
+00:29:19,470 --> 00:29:26,540
+شغل الأكروزين as a lithic enzyme صورة بتوضحالـ
+
+412
+00:29:26,540 --> 00:29:30,220
+event اللى ممكن تصير خلال ال fertilization هى في
+
+413
+00:29:30,220 --> 00:29:35,380
+عندى ال oocyte هى في عندى ال sperm ال sperm makes
+
+414
+00:29:35,380 --> 00:29:39,120
+contact with egg الخطوة الأولى ال acrosome طبعا
+
+415
+00:29:39,120 --> 00:29:42,080
+قولناها دى باللون الأخضر اللى بتكون دايما في مقدمة
+
+416
+00:29:42,080 --> 00:29:47,380
+رأس النطوة الذكية ال event رقم اتنين ان ال
+
+417
+00:29:47,380 --> 00:29:50,720
+acrosome react with زونابلوسيدا من خلال
+
+418
+00:29:50,720 --> 00:29:53,640
+زونابلوسيدا رقم تلاتة فبفرز ال lytic enzyme اللى
+
+419
+00:29:53,640 --> 00:29:57,910
+بتعمل على التدميريعني كأنه بيعمل عملية opening أو
+
+420
+00:29:57,910 --> 00:30:01,050
+holes في الـ Zoonapalus ده الـ acrosome reacts
+
+421
+00:30:01,050 --> 00:30:07,370
+with pre-vital space يعني هذا الـ space اللي احنا
+
+422
+00:30:07,370 --> 00:30:11,370
+شايفينه هذا الـ space اللونه زي لون الزهر الفاتح
+
+423
+00:30:11,370 --> 00:30:16,610
+بنتسميه pre-vital space طبعا هنا هيلاقي granules
+
+424
+00:30:16,610 --> 00:30:20,250
+بسيطة بنتسميها protein receptor هذا هيتصل فيها لـ
+
+425
+00:30:20,250 --> 00:30:24,340
+spermPlasma membrane of sperm and egg تبدأ تعمل
+
+426
+00:30:24,340 --> 00:30:27,580
+fusion مع بعض من البعض وبتدخل بس النواة الخاصة
+
+427
+00:30:27,580 --> 00:30:32,260
+بالـ sperm يعني بمعنى أخر النواة الخاصة بالـ sperm
+
+428
+00:30:32,260 --> 00:30:35,420
+هي التي تشارك في عملية ال fertilization كمان شوية،
+
+429
+00:30:35,420 --> 00:30:38,540
+حلاج الكلام يختلف، حلاج النواة والـ metacondria،
+
+430
+00:30:38,540 --> 00:30:44,320
+ويلها تفاصيل تانية خلّيني أشوف الفيديو اللي بتكلم
+
+431
+00:30:44,320 --> 00:30:49,000
+عن عملية ال fertilization وقريتها وأهم ال event
+
+432
+00:30:49,000 --> 00:30:50,280
+اللي ممكن تحصل خلالها
+
+433
+00:30:57,290 --> 00:31:01,210
+عندما يحدث الهجوم خلال التجارب، يتم دفع ما يقارب
+
+434
+00:31:01,210 --> 00:31:07,470
+200 مليون سبرم أو spermatozoa إلى الجلد. هم
+
+435
+00:31:07,470 --> 00:31:10,090
+يسافرون من خلال عصرهم، ويحركوا من خلال حركتين مثل
+
+436
+00:31:10,090 --> 00:31:14,850
+الـ whip أو الـ flagella، ومن ثم تدفعهم من خلال
+
+437
+00:31:14,850 --> 00:31:17,830
+عضلات عضلات عضلة عضلة عضلة عضلة عضلة عضلة عضلة
+
+438
+00:31:17,830 --> 00:31:18,530
+عضلة عضلة عضلة عضلة عضلة عضلة عضلة عضلة عضلة عضلة
+
+439
+00:31:18,530 --> 00:31:19,170
+عضلة عضلة عضلة عضلة عضلة عضلة عضلة عضلة عضلة عضلة
+
+440
+00:31:19,170 --> 00:31:24,710
+عضلة عضلة عضلة عضلة عضلة عضلة
+
+441
+00:31:24,710 --> 00:31:28,670
+عضلة عضلة عضلة عضلة عضلة عضقبل 200 سبيرمتازوه فقط
+
+442
+00:31:28,670 --> 00:31:32,810
+ستصل إلى الـ secondary oocyte في البرمجل و من هذه
+
+443
+00:31:32,810 --> 00:31:37,090
+فقط واحدة سوف تفردلها الفرداليزية لا يمكن أن تحدث
+
+444
+00:31:37,090 --> 00:31:42,870
+حتى أن اتجهت اتجاهين كتابة و اتجاه الاكراسومال
+
+445
+00:31:42,870 --> 00:31:48,470
+يمكن ان تأخذ ساعات كتابة و اتجاه الاكراسومال لا
+
+446
+00:31:48,470 --> 00:31:53,920
+يمكن ان تأخذ ساعاتولكن تحريكات من الجدران والجدران
+
+447
+00:31:53,920 --> 00:31:58,220
+التجاري تحرير ممكنات البلازمة اللي تقع في جدران
+
+448
+00:31:58,220 --> 00:32:03,280
+السفرمتازوة أو الـ Acrosome تتسبب في الممكنات تصبح
+
+449
+00:32:03,280 --> 00:32:07,420
+أكتر مطرقة، وهذا يساعد في تحريك السفرمتازوة لأحداث
+
+450
+00:32:07,420 --> 00:32:13,360
+الترتيب السفرمتازوة تصبح حيبر اكتر، فالجسدها تضرب
+
+451
+00:32:13,360 --> 00:32:18,220
+أكتر بشكل عادى، ومصادرها تتحرك من الجهدالـ
+
+452
+00:32:18,220 --> 00:32:20,880
+Capacitated Spermatozoa تتحرك من خلال كورونا
+
+453
+00:32:20,880 --> 00:32:22,780
+راديايدا، عبارة عن عبارة عن عبارة عن عبارة عن
+
+454
+00:32:22,780 --> 00:32:24,000
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+455
+00:32:24,000 --> 00:32:24,620
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+456
+00:32:24,620 --> 00:32:25,480
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+457
+00:32:25,480 --> 00:32:25,700
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+458
+00:32:25,700 --> 00:32:25,880
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+459
+00:32:25,880 --> 00:32:27,700
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+460
+00:32:27,700 --> 00:32:45,140
+عبارة عن عبارة
+
+461
+00:32:46,040 --> 00:32:51,240
+عندما يتم إطلاق مصادر الأنزيمات للـ Acrosome هذه
+
+462
+00:32:51,240 --> 00:32:54,180
+الأنزيمات ساعدت في تجهيز طريقة من خلال الـ
+
+463
+00:32:54,180 --> 00:32:57,460
+Zonopelucida يسمح بشركة الـ Spermatozoa بإدخال
+
+464
+00:32:57,460 --> 00:33:01,700
+مخطط الـ Perivitalin و تصل إلى مصادر الـ Plasma من
+
+465
+00:33:01,700 --> 00:33:05,920
+مصادر الـ Oocyte الثانوية التي تتعامل معها لتأكيد
+
+466
+00:33:05,920 --> 00:33:08,660
+أن فقط واحد من الـ Spermatozoa يدخل مصادر الـ
+
+467
+00:33:08,660 --> 00:33:13,410
+Zonopelucida و يتعامل مع مصادر الـ OocyteFusion of
+
+468
+00:33:13,410 --> 00:33:16,570
+the spermatozoan and oocyte membranes activates a
+
+469
+00:33:16,570 --> 00:33:21,090
+fast and a slow block to polyspermy. During fast
+
+470
+00:33:21,090 --> 00:33:24,450
+block to polyspermy, after fusion, the oocyte
+
+471
+00:33:24,450 --> 00:33:28,530
+membrane depolarizes, preventing other spermatozoa
+
+472
+00:33:28,530 --> 00:33:34,150
+from fusing with it. slow طبعا هنا بتكلم ما هي
+
+473
+00:33:34,150 --> 00:33:38,410
+الألية اللتي تستخدمها البويضة لمنع قلقيها بأكثر من
+
+474
+00:33:38,410 --> 00:33:43,160
+سبقين و هذا هنشرحه كمان شويةوالمجلد لـ Polyspermia
+
+475
+00:33:43,160 --> 00:33:48,400
+هو أيضًا مدفع من هذا الانتقال. في مجلد مدفع لـ
+
+476
+00:33:48,400 --> 00:33:51,840
+Polyspermia، يتم إطلاق حوار من الكالسيوم
+
+477
+00:33:51,840 --> 00:33:56,260
+الانتقالية، يسبب فيها عصباء صغيرة وكورتقالات تحت
+
+478
+00:33:56,260 --> 00:34:00,300
+عصباء الـ Oocyte Membrane لإطلاق مواصلتهم، يجعل
+
+479
+00:34:00,300 --> 00:34:05,100
+الـ ZP3 غير مفتوح ويجعل الـ Zonopelucida غير مدفع.
+
+480
+00:34:05,680 --> 00:34:09,180
+عندما يدخل الـ spermatozoon، يتعامل الـ Oocyte
+
+481
+00:34:09,180 --> 00:34:16,940
+ميوزس 2و يتطور إلى الـ female pronucleus في هذه
+
+482
+00:34:16,940 --> 00:34:21,060
+الوقت، الـ sperm يتطور إلى الـ male pronucleus و
+
+483
+00:34:21,060 --> 00:34:25,680
+الـ two pronuclei يتجمدوا لتصميم نوكليس ديبلويد أو
+
+484
+00:34:25,680 --> 00:34:30,820
+زيجوت طبعا
+
+485
+00:34:30,820 --> 00:34:37,120
+هنا اتكلم عن أكثر من حالة على سبيل المثال، اتكلم
+
+486
+00:34:37,120 --> 00:34:40,840
+عن الألية التي يتم في عملية ال penetrationدور الـ
+
+487
+00:34:40,840 --> 00:34:47,960
+ZE3 الموجودة بالوسداء كيف الـ oocyte تمنع التوقيع
+
+488
+00:34:47,960 --> 00:34:52,120
+نفسها بأكثر من sperm من خلال إفراز بعض المُركّبات
+
+489
+00:34:52,120 --> 00:34:57,620
+كيف يتكون الزيجات أيضًا طبعًا عملية منع التوقيع بـ
+
+490
+00:34:57,620 --> 00:35:01,340
+two sperm لها طريقتين سنتحدث عنهم واحدة سلوك واحدة
+
+491
+00:35:01,340 --> 00:35:05,640
+فصل سأشرحهم في الفيديو بشكل مقتصر وسنتحدث عنهم إن
+
+492
+00:35:05,640 --> 00:35:08,920
+شاء الله طبعًا
+
+493
+00:35:10,340 --> 00:35:18,520
+بعد اتفاق الـ Spermatozoa الوارثية
+
+494
+00:35:18,520 --> 00:35:21,380
+للمادة الوارثية في الـ site الخاص بالـ sperm في
+
+495
+00:35:21,380 --> 00:35:24,540
+الـ cytoplasm الخاص بالـ oocyte عشان يبدأ عملية
+
+496
+00:35:24,540 --> 00:35:27,560
+الاندماج ما بين الـ maternal و الـ maternal
+
+497
+00:35:27,560 --> 00:35:33,240
+nucleic acid في بعضهم بقول ليه و بعض العلماء هنا
+
+498
+00:35:33,240 --> 00:35:36,500
+فيه نقطة اختلاف Also, metachondria located in the
+
+499
+00:35:36,500 --> 00:35:39,900
+sperm neck enter the egg, they do not contribute
+
+500
+00:35:41,270 --> 00:35:44,750
+metachondrial complement of the zygote يعني في ناس
+
+501
+00:35:44,750 --> 00:35:47,710
+بتحكي و علماء بتقول أن الـ metachondria الموجودة
+
+502
+00:35:47,710 --> 00:35:52,150
+في الـ neck أو الخاصة بالـ sperm تدخل مع المادة
+
+503
+00:35:52,150 --> 00:35:57,610
+الوراثية داخل الـ cytoplasm الخاص بالـ oocyte ولكن
+
+504
+00:35:57,610 --> 00:36:01,670
+لا تساهم في تكوين الـ zygote هل هذا صحيح؟ لأن في
+
+505
+00:36:01,670 --> 00:36:04,310
+ناس تانية بتقول لك لأ مافي عندي metachondrial
+
+506
+00:36:04,310 --> 00:36:07,070
+paternal metachondrial دي يعني مافي حاجة اسمها
+
+507
+00:36:07,070 --> 00:36:09,890
+paternal metachondrial دي يعني ممكن ألجيها في
+
+508
+00:36:09,890 --> 00:36:13,990
+الجنين عشان كدهصار في عنده اختلاف هل الـ DNA الخاص
+
+509
+00:36:13,990 --> 00:36:17,470
+في الـ metacondria الموجود في الأجنة تتبع ال male
+
+510
+00:36:17,470 --> 00:36:21,190
+و لا يتبع ال female بمعنى أخر خاص بالأب paterna
+
+511
+00:36:21,190 --> 00:36:25,990
+ولا خاص بالأم materna وهذا كان نقطة خلاف كبير جدا
+
+512
+00:36:25,990 --> 00:36:30,570
+ما بين العلماء على هذا الموضوع ولكن الموضوع أنه في
+
+513
+00:36:30,570 --> 00:36:34,710
+حاجة اسمها autophage system بتعمل engulfing لل
+
+514
+00:36:34,710 --> 00:36:37,950
+paterna الميتاكندريا الدياني إن دخلت الcytoplasma
+
+515
+00:36:37,950 --> 00:36:41,120
+عشان كده جدا نادر ما بتشوفالـ Paternal
+
+516
+00:36:41,120 --> 00:36:45,100
+Mitochondrial في البشر الـ sperm تشغّل الـ
+
+517
+00:36:45,100 --> 00:36:50,760
+Centrosome اللي محتاجه لتنزيف الجسد موجود في
+
+518
+00:36:50,760 --> 00:36:56,540
+المادة الوراثية للأب بشكل أساسي مهم جدا علشان يكمل
+
+519
+00:36:56,540 --> 00:37:01,340
+عملية الغسام الخاصة بالجنين ال paternal
+
+520
+00:37:01,340 --> 00:37:04,620
+mitochondrial اللي حكينا فيها اندخلت خلال عملية ال
+
+521
+00:37:04,620 --> 00:37:09,640
+fertilization ووصلت لهاالـfertilized oocyte أو
+
+522
+00:37:09,640 --> 00:37:12,760
+الـCytoplasma الخاص بالـfertilized oocyte هتلاقي
+
+523
+00:37:12,760 --> 00:37:17,420
+مباشرة فيه إلها elimination يعني بتترد أو بيصيلها
+
+524
+00:37:17,420 --> 00:37:21,300
+breakdown أو degeneration بفعل إنزين يسميه
+
+525
+00:37:21,300 --> 00:37:27,660
+autophagocyte و لكن الطريقة و الميكنزم حتى الآن في
+
+526
+00:37:27,660 --> 00:37:29,300
+عندي limitation
+
+527
+00:37:34,850 --> 00:37:41,310
+المتوفرة عن هذا السبب أو عن هذه القالية The
+
+528
+00:37:41,310 --> 00:37:45,850
+inheritance of metachondria اتفق العلماء أن معظم
+
+529
+00:37:45,850 --> 00:37:49,070
+الـ metachondrial في أجسادنا inherited from mother
+
+530
+00:37:49,070 --> 00:37:54,270
+so this type of metachondrial is maternal
+
+531
+00:37:54,270 --> 00:37:57,310
+inheritance يعني معظم الـ metachondrial في أجسادنا
+
+532
+00:37:57,310 --> 00:38:02,350
+أصلها ومصدرها الأمبسيط الفيرتاليزيات البيتيرنا
+
+533
+00:38:02,350 --> 00:38:02,990
+البيتيرنا البيتيرنا البيتيرنا البيتيرنا البيتيرنا
+
+534
+00:38:02,990 --> 00:38:12,570
+البيتيرنا البيتيرنا البيتيرنا البيتيرنا
+
+535
+00:38:12,570 --> 00:38:14,250
+البيتيرنا البيتيرنا البيتيرنا البيتيرنا البيتيرنا
+
+536
+00:38:14,250 --> 00:38:16,110
+البيتيرنا البيتيرنا البيتيرنا البيتيرنا البيتيرنا
+
+537
+00:38:16,110 --> 00:38:19,210
+البيتيرنا
+
+538
+00:38:19,210 --> 00:38:23,750
+البيتيرنا
+
+539
+00:38:23,750 --> 00:38:26,610
+البيتيرنا البيتيرنا البيتيرنا البيتيرنا البيتيرنا
+
+540
+00:38:26,610 --> 00:38:27,990
+البيتيرنا البيتيرنا البيتيرنا البيتيرنا البيتيرنا
+
+541
+00:38:27,990 --> 00:38:28,050
+البيتيرنا البيتيرنا البيتيرنا البيتيرنا البيتيرنا
+
+542
+00:38:28,050 --> 00:38:28,050
+البيتيرنا البيتيرنا البيتيرنا البيتيرنا البيتيرنا
+
+543
+00:38:28,050 --> 00:38:31,190
+البيRecently, several authors have found that
+
+544
+00:38:31,190 --> 00:38:33,270
+sperm mitochondrial DNA remains in the
+
+545
+00:38:33,270 --> 00:38:36,750
+preimplantation embryo دراسات لما اتطورت و الأبحاث
+
+546
+00:38:36,750 --> 00:38:40,110
+وجدوا انه في مرحلة ال preimplantation embryo، ال
+
+547
+00:38:40,110 --> 00:38:43,870
+embryo جاب لعملية ال implantation وجدوا في عندي
+
+548
+00:38:43,870 --> 00:38:47,650
+بعض ال maternal mitochondrial DNA، طبعا هذا تفسيره
+
+549
+00:38:47,890 --> 00:38:51,710
+إنه قد يكون هناك خلل في الـ autophage system ففي
+
+550
+00:38:51,710 --> 00:38:55,450
+بعض الـ maternal metacondrial DNA scabbing وظلت
+
+551
+00:38:55,450 --> 00:38:58,630
+كما هي بدون ما يصيرها degeneration this finding ..
+
+552
+00:38:58,630 --> 00:39:02,570
+this finding suggest that spare metacondrial DNA
+
+553
+00:39:02,570 --> 00:39:05,850
+is replicated compound and is not actively
+
+554
+00:39:05,850 --> 00:39:09,930
+eliminated during infragenesis ببساطة جدا ماصارداش
+
+555
+00:39:09,930 --> 00:39:13,250
+من elimination بفعل خلل في ال autophage system
+
+556
+00:39:13,250 --> 00:39:17,880
+وصار هي replication فتضعفت بكمية موجودةفوجدناها
+
+557
+00:39:17,880 --> 00:39:22,180
+فيما بعد and the other explanation is that the
+
+558
+00:39:22,180 --> 00:39:25,840
+mitophage mechanism of the oocyte is defect ببساطة
+
+559
+00:39:25,840 --> 00:39:30,260
+جدا يعني في عدة سببين السبب الأول أن الميتوفاج ..
+
+560
+00:39:30,260 --> 00:39:33,380
+الميكنزم اللي سميته autophage الخاص بالـ oocyte
+
+561
+00:39:33,380 --> 00:39:37,280
+defect أو السبب التاني أنه صار لها replication
+
+562
+00:39:37,280 --> 00:39:40,800
+بكميات كبيرة جدا فأجد مابدتش تشغل ال autophage مش
+
+563
+00:39:40,800 --> 00:39:46,170
+هتقضي عليها فبالتالي هذاصارت حالة .. طبعا ما
+
+564
+00:39:46,170 --> 00:39:49,350
+اكتشفوهاش بكمية كبيرة جدا فقط حالات معدودة .. 7 ..
+
+565
+00:39:49,350 --> 00:39:52,730
+8 .. 9 حالات حتى الآن اكتشفوهم حتى بالـ whole
+
+566
+00:39:52,730 --> 00:39:55,830
+genome sequencing أو الـ DNA Sequencing لما عملوا
+
+567
+00:39:55,830 --> 00:39:59,370
+الـ DNA Sequencing للمادة الوراقية الموجودة في الـ
+
+568
+00:39:59,370 --> 00:40:01,530
+embryo لاجوا عندي تلاتة .. واحدة paternal ..
+
+569
+00:40:01,530 --> 00:40:04,430
+متكندرية واحدة maternal .. متكندرية واحدة paternal
+
+570
+00:40:04,430 --> 00:40:08,510
+.. متكندرية او لاجوا تلاتة .. واحدة خاصة بالأب ..
+
+571
+00:40:08,510 --> 00:40:11,610
+واحدة خاصة بالأم .. والتالتة فيما بعد اكتشفوا انها
+
+572
+00:40:11,610 --> 00:40:14,700
+عبارة عن paternal .. متكندرية .. DNA sequenceيعني
+
+573
+00:40:14,700 --> 00:40:18,700
+دليل أن الـ metacondria الموجودة في الـ spam قد
+
+574
+00:40:18,700 --> 00:40:24,480
+تتواجد و تضاعف و تبقى في الـ imprint كده هنخلص هذا
+
+575
+00:40:24,480 --> 00:40:27,680
+الموضوع و هذه المحاضرة عند هذا الحد ان شاء الله
+
+576
+00:40:27,680 --> 00:40:32,000
+على أمل أن نلتقي في المحاضرة القادمة ان شاء الله
+
+577
+00:40:32,000 --> 00:40:33,780
+تم تم في رعاية الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/g1I29Wemtw4_raw.json b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/g1I29Wemtw4_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..3598cc40afe32faa1cc560529f70c91cd790751d
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/g1I29Wemtw4_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 2978, "start": 1.16, "end": 29.78, "text": "بسم الله الرحمن الرحيم والصلاة والسلام على أشرف المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا الأعزاء أرجو من الله الكريم أن تكونوا جميعًا بخير اليوم سوف نستكمل ما بدأنا فيه في المحاضرة السابقة المتعلقة بالإكزي الـ Intracytoplasmic sperm injection حيث تحدثنا في المحاضرة السابقة عن القالية sperm catching", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 16070, 9381, 15040, 3660, 16070, 3794, 37440, 15844, 5551, 8592, 28480, 9673, 2288, 3794, 1211, 9957, 8608, 25708, 8315, 3714, 35571, 3215, 4032, 3615, 23942, 19753, 43761, 4032, 9381, 5016, 3555, 3224, 5551, 7435, 2304, 3615, 9957, 23032, 15040, 3555, 8315, 16247, 3615, 11622, 16606, 5551, 47341, 2407, 9154, 21984, 33251, 16572, 2304, 14739, 6055, 30544, 14407, 10874, 2304, 40228, 14111, 995, 4724, 9778, 13546, 45595, 20498, 8608, 38688, 8717, 14851, 24793, 1211, 19446, 47525, 10721, 8315, 8978, 3224, 8978, 9673, 5016, 46958, 25720, 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" التي", "probability": 0.92822265625}, {"start": 49.39, "end": 49.77, "word": " يمكن", "probability": 0.9814453125}, {"start": 49.77, "end": 49.93, "word": " أن", "probability": 0.77587890625}, {"start": 49.93, "end": 50.51, "word": " تستخدم", "probability": 0.9615478515625}, {"start": 50.51, "end": 50.93, "word": " بدل", "probability": 0.8505859375}, {"start": 50.93, "end": 51.31, "word": " المينا", "probability": 0.77880859375}, {"start": 51.31, "end": 51.49, "word": " الـ", "probability": 0.698974609375}, {"start": 51.49, "end": 52.03, "word": " PVP", "probability": 0.8505859375}, {"start": 52.03, "end": 52.71, "word": " وما", "probability": 0.940673828125}, {"start": 52.71, "end": 52.91, "word": " هو", "probability": 0.97802734375}, {"start": 52.91, "end": 53.31, "word": " السبب", "probability": 0.9890950520833334}, {"start": 53.31, "end": 53.57, "word": " الذي", "probability": 0.73974609375}, {"start": 53.57, "end": 54.21, "word": " جعلها", "probability": 0.966796875}, {"start": 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{"start": 76.49, "end": 77.17, "word": " القدرة", "probability": 0.7864583333333334}, {"start": 77.17, "end": 77.33, "word": " على", "probability": 0.87255859375}, {"start": 77.33, "end": 77.93, "word": " الحركة", "probability": 0.9847005208333334}, {"start": 77.93, "end": 78.89, "word": " تمهيدا", "probability": 0.9677734375}, {"start": 78.89, "end": 79.73, "word": " لاستخدامه", "probability": 0.8931477864583334}, {"start": 79.73, "end": 79.87, "word": " في", "probability": 0.96044921875}, {"start": 79.87, "end": 80.39, "word": " عملية", "probability": 0.9918619791666666}, {"start": 80.39, "end": 81.33, "word": " الحطب", "probability": 0.7421061197916666}, {"start": 81.33, "end": 82.19, "word": " once", "probability": 0.5029296875}, {"start": 82.19, "end": 82.47, "word": " the", "probability": 0.7880859375}, {"start": 82.47, "end": 83.33, "word": " spermatozoa", "probability": 0.7384033203125}, {"start": 83.33, "end": 83.57, "word": " is", "probability": 0.9541015625}, {"start": 83.57, "end": 83.97, "word": " catch", "probability": 0.7314453125}, {"start": 83.97, "end": 84.43, "word": " or", "probability": 0.73095703125}, {"start": 84.43, "end": 84.75, "word": " pick", "probability": 0.68994140625}, {"start": 84.75, "end": 85.07, "word": " up", "probability": 0.91796875}, {"start": 85.07, "end": 85.93, "word": " it", "probability": 0.84375}, {"start": 85.93, "end": 86.07, "word": " is", "probability": 0.8046875}, {"start": 86.07, "end": 86.55, "word": " appeared", "probability": 0.5517578125}, {"start": 86.55, "end": 87.19, "word": " necessary", "probability": 0.9384765625}, {"start": 87.19, "end": 88.45, "word": " immobilized", "probability": 0.95458984375}, {"start": 88.45, "end": 89.11, "word": " before", "probability": 0.87646484375}, {"start": 89.11, "end": 89.63, "word": " injection", "probability": 0.8984375}], "temperature": 1.0}, {"id": 4, "seek": 11793, "start": 89.89, "end": 117.93, "text": "بمعنى آخر طالما انت عملت catching ل3، 4، 5، 6 sperm هتستخدمهم في عملية ال injection لازم تخليهم immobilized يعني immutable جبل ما تستخدمهم في عملية ال injection فبالتالي كيف تتم عملية ال immobilization for spermatozoa regardless of the fact that under normal in vivo condition no sperm tail", "tokens": [3555, 2304, 3615, 1863, 7578, 19753, 34740, 23032, 6027, 15042, 16472, 2655, 6225, 42213, 2655, 16124, 5296, 18, 12399, 1017, 12399, 1025, 12399, 1386, 32899, 8032, 2655, 14851, 9778, 40448, 16095, 8978, 6225, 42213, 10632, 2423, 22873, 5296, 31377, 2304, 6055, 9778, 20292, 16095, 3397, 21725, 1602, 37495, 22653, 3397, 32148, 10874, 36150, 19446, 6055, 14851, 9778, 40448, 16095, 8978, 6225, 42213, 10632, 2423, 22873, 6156, 3555, 6027, 2655, 6027, 1829, 9122, 33911, 6055, 39237, 6225, 42213, 10632, 2423, 3397, 21725, 2144, 337, 32899, 2513, 4765, 64, 10060, 295, 264, 1186, 300, 833, 2710, 294, 30689, 4188, 572, 32899, 6838], "avg_logprob": -0.1680074204312693, "compression_ratio": 1.6141078838174274, "no_speech_prob": 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"probability": 0.70166015625}], "temperature": 1.0}, {"id": 5, "seek": 14763, "start": 118.24, "end": 147.64, "text": "will be entered in the oocyte immobilized or spermatozoa has two beneficial effects في الوضع الطبيعي لما يصير injection في الوضع الطبيعي لل oocyte و fertilization لل oocyte مافي tail يساهم في عملية مافي tail بيدخل داخل الخلية يعني بمعنى آخر ال tail له علاقة في ال fertilization إن كان طبيعي ولكن ما بدخل داخل الخلية لأن ال fertilization مهم جدا من أوامل وجود", "tokens": [17044, 312, 9065, 294, 264, 277, 31078, 975, 3397, 21725, 1602, 420, 24152, 15677, 15151, 23254, 575, 732, 14072, 5065, 8978, 2423, 2407, 11242, 3615, 41950, 21292, 3615, 1829, 5296, 15042, 7251, 9381, 13546, 22873, 8978, 2423, 2407, 11242, 3615, 41950, 21292, 3615, 1829, 24976, 277, 31078, 975, 4032, 18512, 2144, 24976, 277, 31078, 975, 19446, 41185, 6838, 7251, 3794, 995, 16095, 8978, 6225, 42213, 10632, 19446, 41185, 6838, 4724, 25708, 9778, 1211, 11778, 47283, 1211, 33962, 1211, 10632, 37495, 22653, 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{"start": 137.3, "end": 137.52, "word": " له", "probability": 0.427734375}, {"start": 137.52, "end": 137.9, "word": " علاقة", "probability": 0.9871419270833334}, {"start": 137.9, "end": 138.04, "word": " في", "probability": 0.865234375}, {"start": 138.04, "end": 138.14, "word": " ال", "probability": 0.92333984375}, {"start": 138.14, "end": 138.84, "word": " fertilization", "probability": 0.952880859375}, {"start": 138.84, "end": 139.12, "word": " إن", "probability": 0.84423828125}, {"start": 139.12, "end": 139.3, "word": " كان", "probability": 0.9931640625}, {"start": 139.3, "end": 139.84, "word": " طبيعي", "probability": 0.9814453125}, {"start": 139.84, "end": 141.08, "word": " ولكن", "probability": 0.870361328125}, {"start": 141.08, "end": 141.26, "word": " ما", "probability": 0.96240234375}, {"start": 141.26, "end": 141.82, "word": " بدخل", "probability": 0.7375081380208334}, {"start": 141.82, "end": 142.52, "word": " داخل", "probability": 0.97412109375}, {"start": 142.52, "end": 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immobilization قبل عملية ال injection any possible damage to the cytoskeleton caused by a motile sperm is theoretically ineligible بمعنى آخر أنا لما أجي أعمل", "tokens": [6027, 39184, 6838, 11203, 8592, 7649, 7251, 9381, 13546, 9848, 24433, 30767, 1829, 19446, 13412, 38688, 8315, 11296, 8978, 9673, 5016, 46958, 2288, 9307, 21136, 16758, 28671, 35525, 19452, 8978, 33688, 7435, 11622, 1829, 2423, 39184, 6838, 37893, 3714, 16095, 9122, 2655, 13546, 5296, 33456, 2423, 22873, 8608, 38688, 7251, 24401, 12984, 4724, 5172, 30241, 2978, 5551, 12610, 11331, 26108, 3660, 5551, 39648, 32239, 3224, 13412, 2407, 39896, 5551, 16095, 10632, 16472, 8717, 25957, 1211, 32899, 3397, 21725, 2144, 12174, 36150, 6225, 42213, 10632, 2423, 22873, 604, 1944, 4344, 281, 264, 40248, 329, 330, 14806, 7008, 538, 257, 2184, 794, 32899, 307, 29400, 294, 338, 11292, 4724, 2304, 3615, 1863, 7578, 19753, 34740, 41850, 5296, 15042, 5551, 7435, 1829, 5551, 25957, 1211], "avg_logprob": -0.22675304635753477, 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ال spermاترزوه هاد المنطقة هي عبارة عن منطقة القطع طريقة تالتة بيستخدموها و هي طريقة ال aspiration او ال repeated aspiration ان نعمل suction releasing releasing suction و هكذا بشكل متتالي كدا انا بجبر يصير في عملية damage ل ال sperm تالت", "tokens": [5172, 4117, 28259, 39896, 19913, 3224, 2288, 32239, 2423, 32899, 39627, 15730, 25124, 28820, 11778, 20292, 1211, 16472, 1975, 8315, 12174, 9566, 34268, 2423, 32899, 9307, 2288, 11622, 2407, 3224, 8032, 18513, 9673, 1863, 9566, 28671, 39896, 6225, 3555, 9640, 3660, 18871, 9154, 9566, 28671, 25062, 9566, 3615, 23032, 16572, 28671, 6055, 6027, 2655, 3660, 4724, 1829, 14851, 9778, 40448, 2407, 11296, 4032, 39896, 23032, 16572, 28671, 2423, 44565, 1975, 2407, 2423, 10477, 44565, 16472, 8717, 25957, 1211, 40431, 16327, 16327, 40431, 4032, 8032, 4117, 15730, 4724, 8592, 28820, 44650, 2655, 6027, 1829, 9122, 28259, 1975, 8315, 4724, 7435, 26890, 7251, 9381, 13546, 8978, 6225, 42213, 10632, 4344, 5296, 2423, 32899, 6055, 6027, 2655], "avg_logprob": 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0.93603515625}, {"start": 464.29, "end": 464.79, "word": " عملية", "probability": 0.9384765625}, {"start": 464.79, "end": 465.43, "word": " damage", "probability": 0.77490234375}, {"start": 465.43, "end": 465.83, "word": " ل", "probability": 0.73828125}, {"start": 465.83, "end": 466.39, "word": " ال", "probability": 0.42919921875}, {"start": 466.39, "end": 466.75, "word": " sperm", "probability": 0.984375}, {"start": 466.75, "end": 468.43, "word": " تالت", "probability": 0.477783203125}], "temperature": 1.0}, {"id": 17, "seek": 49890, "start": 469.58, "end": 498.9, "text": "أو بسرع في عملية ال sperm immobilization طريقة الرابعة وهي الأكثر استخداما حاليا بسبب تطور الأدوات المستخدمة هي طريقة ال laser وهي ببساطة جدا في عندي مؤشر زي مؤشر القناص بجيبه على منتصف الدل وبعمل click بالماوس او بكنوب معين كنوب معين زر معين بطلق شعاع laser هذا شعاع laser بدرب", "tokens": [10721, 2407, 4724, 3794, 2288, 3615, 8978, 6225, 42213, 10632, 2423, 32899, 3397, 21725, 2144, 23032, 16572, 28671, 34892, 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"word": " بكنوب", "probability": 0.65899658203125}, {"start": 492.42, "end": 493.12, "word": " معين", "probability": 0.964599609375}, {"start": 493.12, "end": 494.6, "word": " كنوب", "probability": 0.7181803385416666}, {"start": 494.6, "end": 495.12, "word": " معين", "probability": 0.983154296875}, {"start": 495.12, "end": 495.46, "word": " زر", "probability": 0.770263671875}, {"start": 495.46, "end": 495.96, "word": " معين", "probability": 0.993408203125}, {"start": 495.96, "end": 496.96, "word": " بطلق", "probability": 0.877685546875}, {"start": 496.96, "end": 497.3, "word": " شعاع", "probability": 0.8474934895833334}, {"start": 497.3, "end": 497.6, "word": " laser", "probability": 0.41015625}, {"start": 497.6, "end": 497.82, "word": " هذا", "probability": 0.72900390625}, {"start": 497.82, "end": 498.06, "word": " شعاع", "probability": 0.9562174479166666}, {"start": 498.06, "end": 498.34, "word": " laser", "probability": 0.84912109375}, {"start": 498.34, "end": 498.9, "word": " بدرب", "probability": 0.765380859375}], "temperature": 1.0}, {"id": 18, "seek": 51962, "start": 499.14, "end": 519.62, "text": "الـ cell membrane فبعمل قطع بسيط فيه أو بضرب الـ cell membrane الخاص بالـ tail of spermatozoa فبعمل قطع في spermatozoa وهو قطع بسيط مما يؤدي إلى عمل spermatozoa immobilization طبعا في دراسات اختلفت في", "tokens": [6027, 39184, 2815, 19651, 6156, 3555, 25957, 1211, 12174, 9566, 3615, 4724, 3794, 1829, 9566, 8978, 3224, 34051, 4724, 11242, 25513, 2423, 39184, 2815, 19651, 33962, 33546, 20666, 39184, 6838, 295, 32899, 2513, 4765, 64, 6156, 3555, 25957, 1211, 12174, 9566, 3615, 8978, 32899, 2513, 4765, 64, 37037, 2407, 12174, 9566, 3615, 4724, 3794, 1829, 9566, 3714, 15042, 7251, 33604, 16254, 30731, 6225, 42213, 32899, 2513, 4765, 64, 3397, 21725, 2144, 23032, 3555, 3615, 995, 8978, 11778, 23557, 3794, 9307, 1975, 46456, 46538, 2655, 8978], "avg_logprob": -0.16051961758802102, "compression_ratio": 1.6420454545454546, "no_speech_prob": 3.9577484130859375e-05, "words": [{"start": 499.14, "end": 499.46, "word": "الـ", "probability": 0.5128173828125}, {"start": 499.46, "end": 499.58, "word": " cell", "probability": 0.37841796875}, {"start": 499.58, "end": 500.04, "word": " membrane", "probability": 0.904296875}, {"start": 500.04, "end": 501.0, "word": " فبعمل", "probability": 0.73974609375}, {"start": 501.0, "end": 501.44, "word": " قطع", "probability": 0.9915364583333334}, {"start": 501.44, "end": 502.08, "word": " بسيط", "probability": 0.9927978515625}, {"start": 502.08, "end": 502.66, "word": " فيه", "probability": 0.67333984375}, {"start": 502.66, "end": 502.92, "word": " أو", "probability": 0.5693359375}, {"start": 502.92, "end": 503.56, "word": " بضرب", "probability": 0.7643229166666666}, {"start": 503.56, "end": 504.04, "word": " الـ", "probability": 0.741943359375}, {"start": 504.04, "end": 504.28, "word": " cell", "probability": 0.88818359375}, {"start": 504.28, "end": 504.58, "word": " membrane", "probability": 0.9248046875}, {"start": 504.58, "end": 505.08, "word": " الخاص", "probability": 0.9130859375}, {"start": 505.08, "end": 505.66, "word": " بالـ", "probability": 0.74609375}, {"start": 505.66, "end": 505.88, "word": " tail", "probability": 0.6640625}, {"start": 505.88, "end": 506.06, "word": " of", "probability": 0.72265625}, {"start": 506.06, "end": 506.74, "word": " spermatozoa", "probability": 0.74261474609375}, {"start": 506.74, "end": 507.48, "word": " فبعمل", "probability": 0.903076171875}, {"start": 507.48, "end": 507.82, "word": " قطع", "probability": 0.99462890625}, {"start": 507.82, "end": 508.08, "word": " في", "probability": 0.98291015625}, {"start": 508.08, "end": 509.32, "word": " spermatozoa", "probability": 0.87548828125}, {"start": 509.32, "end": 509.74, "word": " وهو", "probability": 0.849853515625}, {"start": 509.74, "end": 510.06, "word": " قطع", "probability": 0.9938151041666666}, {"start": 510.06, "end": 510.52, "word": " بسيط", "probability": 0.9981689453125}, {"start": 510.52, "end": 511.04, "word": " مما", "probability": 0.95458984375}, {"start": 511.04, "end": 511.5, "word": " يؤدي", "probability": 0.9420572916666666}, {"start": 511.5, "end": 511.82, "word": " إلى", "probability": 0.666015625}, {"start": 511.82, "end": 512.16, "word": " عمل", "probability": 0.9892578125}, {"start": 512.16, "end": 513.74, "word": " spermatozoa", "probability": 0.9468994140625}, {"start": 513.74, "end": 515.0, "word": " immobilization", "probability": 0.9451497395833334}, {"start": 515.0, "end": 517.36, "word": " طبعا", "probability": 0.950927734375}, {"start": 517.36, "end": 517.78, "word": " في", "probability": 0.63330078125}, {"start": 517.78, "end": 518.42, "word": " دراسات", "probability": 0.971923828125}, {"start": 518.42, "end": 519.42, "word": " اختلفت", "probability": 0.960205078125}, {"start": 519.42, "end": 519.62, "word": " في", "probability": 0.9833984375}], "temperature": 1.0}, {"id": 19, "seek": 54147, "start": 520.05, "end": 541.47, "text": "نتائجها ففي دراسة جالت أنه more aggressive mechanical immobilization process للـ Epidermal sperm تساعد على زيادة ال fertilization rate بمعدل من 48 إلى 82 بس بشرط أنه تم تطبيقها على ال spermatozoa اللي جاي من Epidermal يعني من التيسا أو البيسا مش ال ejaculation العادي", "tokens": [29399, 16373, 7435, 11296, 6156, 41185, 11778, 23557, 3794, 3660, 10874, 6027, 2655, 14739, 3224, 544, 10762, 12070, 3397, 21725, 2144, 1399, 24976, 39184, 9970, 327, 966, 304, 32899, 6055, 3794, 995, 22488, 15844, 30767, 1829, 18513, 3660, 2423, 18512, 2144, 3314, 4724, 2304, 22488, 1211, 9154, 11174, 30731, 29097, 4724, 3794, 4724, 46309, 9566, 14739, 3224, 46811, 6055, 9566, 21292, 4587, 11296, 15844, 2423, 32899, 2513, 4765, 64, 13672, 1829, 10874, 47302, 9154, 9970, 327, 966, 304, 37495, 22653, 9154, 16712, 1829, 3794, 995, 34051, 2423, 21292, 3794, 995, 37893, 2423, 10012, 326, 2776, 18863, 995, 16254], "avg_logprob": -0.2405303063416722, "compression_ratio": 1.5099601593625498, "no_speech_prob": 5.364418029785156e-07, 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1919.77, "end": 1920.33, "word": " السليم", "probability": 0.9669596354166666}, {"start": 1920.33, "end": 1921.33, "word": " والشكل", "probability": 0.8878580729166666}, {"start": 1921.33, "end": 1921.83, "word": " المطلوب", "probability": 0.9757080078125}], "temperature": 1.0}, {"id": 69, "seek": 193475, "start": 1922.47, "end": 1934.75, "text": "هنكتفي بهذا القدر في هذه المحاضرة على أمل أن نكمل ما تبقى من محاضرة ال Exe وعملية التلقيح و الحقنص مجهري في المحاضرات القادمة", "tokens": [3224, 1863, 4117, 2655, 41185, 39627, 15730, 25062, 3215, 2288, 8978, 29538, 9673, 5016, 46958, 25720, 15844, 5551, 42213, 14739, 8717, 24793, 1211, 19446, 6055, 3555, 4587, 7578, 9154, 3714, 5016, 46958, 25720, 2423, 2111, 68, 4032, 25957, 1211, 10632, 16712, 1211, 4587, 1829, 5016, 4032, 21542, 4587, 1863, 9381, 3714, 7435, 3224, 16572, 8978, 9673, 5016, 46958, 2288, 9307, 25062, 18513, 46007], "avg_logprob": -0.15502929221838713, "compression_ratio": 1.6115107913669064, "no_speech_prob": 8.940696716308594e-07, "words": [{"start": 1922.47, "end": 1923.01, "word": "هنكتفي", "probability": 0.89443359375}, {"start": 1923.01, "end": 1923.35, "word": " بهذا", "probability": 0.9443359375}, {"start": 1923.35, "end": 1923.79, "word": " القدر", "probability": 0.9905598958333334}, {"start": 1923.79, "end": 1923.97, "word": " في", "probability": 0.9599609375}, {"start": 1923.97, "end": 1924.33, "word": " هذه", "probability": 0.98095703125}, {"start": 1924.33, "end": 1924.97, "word": " المحاضرة", "probability": 0.9864501953125}, {"start": 1924.97, "end": 1925.49, "word": " على", "probability": 0.8046875}, {"start": 1925.49, "end": 1925.83, "word": " أمل", "probability": 0.921630859375}, {"start": 1925.83, "end": 1926.15, "word": " أن", "probability": 0.83447265625}, {"start": 1926.15, "end": 1926.57, "word": " نكمل", "probability": 0.9825846354166666}, {"start": 1926.57, "end": 1926.69, "word": " ما", "probability": 0.904296875}, {"start": 1926.69, "end": 1927.43, "word": " تبقى", "probability": 0.9813232421875}, {"start": 1927.43, "end": 1928.01, "word": " من", "probability": 0.9853515625}, {"start": 1928.01, "end": 1928.53, "word": " محاضرة", "probability": 0.98193359375}, {"start": 1928.53, "end": 1928.69, "word": " ال", "probability": 0.86279296875}, {"start": 1928.69, "end": 1929.07, "word": " Exe", "probability": 0.4417724609375}, {"start": 1929.07, "end": 1930.47, "word": " وعملية", "probability": 0.9063720703125}, {"start": 1930.47, "end": 1931.25, "word": " التلقيح", "probability": 0.82431640625}, {"start": 1931.25, "end": 1931.41, "word": " و", "probability": 0.72802734375}, {"start": 1931.41, "end": 1932.13, "word": " الحقنص", "probability": 0.7591552734375}, {"start": 1932.13, "end": 1932.79, "word": " مجهري", "probability": 0.76611328125}, {"start": 1932.79, "end": 1933.47, "word": " في", "probability": 0.93505859375}, {"start": 1933.47, "end": 1934.21, "word": " المحاضرات", "probability": 0.99169921875}, {"start": 1934.21, "end": 1934.75, "word": " القادمة", "probability": 0.9938151041666666}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1938.0535, "duration_after_vad": 1873.5093749999953}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/kSV23vKKJRo.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/kSV23vKKJRo.srt
new file mode 100644
index 0000000000000000000000000000000000000000..62348d1a37fc4d0616efa94990d76d1987c9c059
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/kSV23vKKJRo.srt
@@ -0,0 +1,2387 @@
+1
+00:00:00,840 --> 00:00:04,860
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:04,860 --> 00:00:10,460
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا 
+
+3
+00:00:10,460 --> 00:00:14,600
+الأعزاء نرجو من الله الكريم أن تكونوا جميعا بخير 
+
+4
+00:00:14,600 --> 00:00:19,980
+وبصحة جيدة استكمالا لما بدأنا فيه من مواضيع متعلقة 
+
+5
+00:00:19,980 --> 00:00:25,240
+بالحقن المجهري أساليبه وأنواعه وطرقه تحدثنا في 
+
+6
+00:00:25,240 --> 00:00:28,340
+المحاضرات السابقة عن الـspermogenesis والـ 
+
+7
+00:00:28,340 --> 00:00:32,600
+oogenesis تحدثنا عن الخطوات التي تمر بها الـ
+
+8
+00:00:32,600 --> 00:00:36,720
+spermocyte من لحظة التصنيع حتى لحظة الـejaculation
+
+9
+00:00:36,720 --> 00:00:40,980
+ثم مرورا بالـ reproductive system الخاص بالفيميل
+
+10
+00:00:40,980 --> 00:00:44,980
+لحظة الـ intercourse من أجل الـ fertilization ثم 
+
+11
+00:00:44,980 --> 00:00:48,800
+تحدثنا عن الـ oogenesis and الفيميل و كيف يحدث
+
+12
+00:00:48,800 --> 00:00:53,360
+عملية الـ reduction في الـ oocyte count تحت مصطلح
+
+13
+00:00:53,360 --> 00:00:59,920
+atresia وصولا إلى سن الرشد ثم مرورا بمراحل الدورة
+
+14
+00:00:59,920 --> 00:01:04,140
+الشهرية menstrual cycle التي تحدث عند السيدة وكم
+
+15
+00:01:04,140 --> 00:01:09,020
+بوايضة تت نفقدها تحت مصطلح atresia بشكل شهري؟ ماهي
+
+16
+00:01:09,020 --> 00:01:13,720
+الهرمونات التي تساهم في إنتاج وانضاج البوايضة؟ متى
+
+17
+00:01:13,720 --> 00:01:17,280
+يحدث التلقيح؟ وأين يحدث التلقيح؟ ماهو الـ corpus
+
+18
+00:01:17,280 --> 00:01:21,690
+luteum؟ ماهو الـ corpus albicans؟ متى يتكون ومتى
+
+19
+00:01:21,690 --> 00:01:27,290
+يندثر أو يتكسّر؟ اليوم سننتقل إلى مربع جديد له
+
+20
+00:01:27,290 --> 00:01:31,990
+علاقة بالميل بشكل أساسي تحت مصطلح sperm assessment
+
+21
+00:01:31,990 --> 00:01:37,170
+،processing and selection وذلك لأن عملية الـ
+
+22
+00:01:37,170 --> 00:01:41,010
+fertilization أو عملية الإخصاب الـ Intracytoplasmic
+
+23
+00:01:41,010 --> 00:01:44,810
+sperm injection تحتاج إلى single sperm لكي تتم
+
+24
+00:01:44,810 --> 00:01:50,790
+بشكل طبيعي وبشكل سليم. إضافة إلى single oocyte يجب 
+
+25
+00:01:50,790 --> 00:01:56,130
+أن تكون mature فبالتالي الإخصاب عملية تحتاج إلى two
+
+26
+00:01:56,130 --> 00:02:00,050
+جاميط، Male جاميط هي single sperm mature و Female
+
+27
+00:02:00,050 --> 00:02:04,390
+جاميط هي oocyte mature. و لكي تحدث عملية الـ
+
+28
+00:02:04,390 --> 00:02:07,850
+fertilization يجب أن يحدث عملية treatment أو 
+
+29
+00:02:07,850 --> 00:02:12,110
+processing للسمين الـ fluid أو للسمين الـ sample أو
+
+30
+00:02:12,110 --> 00:02:16,070
+للسمين الـ sample علشان أقدر أن أحصل على only one
+
+31
+00:02:16,070 --> 00:02:16,910
+single sperm.
+
+32
+00:02:21,890 --> 00:02:26,780
+العملية تحتاج إلى عملية Evaluation للـ Seminal
+
+33
+00:02:26,780 --> 00:02:30,620
+Fluid. تحتاج إلى عملية assessment للـ Seminal Fluid.
+
+34
+00:02:30,620 --> 00:02:35,380
+تحتاج إنك تكتب تقرير صحيح وسليم. المشكلة إن معظم الـ
+
+35
+00:02:35,380 --> 00:02:38,040
+routine lab ما بتقوم بعمل الـ Seminal Fluid
+
+36
+00:02:38,040 --> 00:02:41,700
+Analysis أو الـ Semin Analysis باستثناء المراكز 
+
+37
+00:02:41,700 --> 00:02:45,480
+والمختبرات المتخصصة التي لها علاقة بالـ Andrology 
+
+38
+00:02:45,480 --> 00:02:50,100
+أو التي لها علاقة بأطفال الأنابيب. معظم الطلاب
+
+39
+00:02:50,100 --> 00:02:56,090
+يكون عندهم افتقار في هذا الشق بسبب عدم التمرس وعدم 
+
+40
+00:02:56,090 --> 00:03:00,630
+التدريب والتدرب عليه. لذلك يجب علينا أن نفرض جزء
+
+41
+00:03:00,630 --> 00:03:05,890
+من هذه المحاضرات تتعلق بـ Seminal Process أو 
+
+42
+00:03:05,890 --> 00:03:10,130
+Seminal Analysis. لما أقول أنا عندي infertility
+
+43
+00:03:10,130 --> 00:03:14,190
+Male infertile يعني غير قادر أو عنده مشكلة خليني
+
+44
+00:03:14,190 --> 00:03:18,490
+أسميها في الحصول على طفل. لما أقول عندي Male Sterile
+
+45
+00:03:18,490 --> 00:03:22,850
+يعني ذكر عقيم لا يستطيع أن ينجب سواء كان بالطريقة
+
+46
+00:03:22,850 --> 00:03:27,710
+الطبيعية أو بالطريقة الصناعية من خلال الحقن 
+
+47
+00:03:27,710 --> 00:03:34,930
+المجهرّي. ومع ذلك صنّف الـ WHO بعض الذكور على أنه
+
+48
+00:03:34,930 --> 00:03:40,540
+Proven Fertile, fertile, subfertile, sterile. طبعا
+
+49
+00:03:40,540 --> 00:03:44,980
+هذا يعتمد على المقدر على الإنجاب بشكل طبيعي، المقدر
+
+50
+00:03:44,980 --> 00:03:48,320
+على الإنجاب بعد التلقيح الصناعي، وكيف تكون الـ semen
+
+51
+00:03:48,320 --> 00:03:53,660
+parameter. فبالتالي وجدوا أن الـ seminal analysis أو
+
+52
+00:03:53,660 --> 00:03:59,600
+تحليل السائل عند الذكور هو عبارة عن أول فحص يطلب 
+
+53
+00:03:59,600 --> 00:04:04,930
+من أجل تشخيص القدرة الإنجابية عند الرجل. We can
+
+54
+00:04:04,930 --> 00:04:08,330
+evaluate the fertility status for any male person 
+
+55
+00:04:08,330 --> 00:04:12,890
+by using seminal analysis as a fair system. بناء
+
+56
+00:04:12,890 --> 00:04:15,930
+على الـ seminal analysis ممكن أن أحصل على بعض الـ
+
+57
+00:04:15,930 --> 00:04:20,490
+information التي تتعلق بالـ functional of sperm 
+
+58
+00:04:20,490 --> 00:04:23,730
+production by testis. هل الـ testis بتفرز لي و
+
+59
+00:04:23,730 --> 00:04:29,390
+بتنتج لي sperm بشكل كافي وبالكمية المطلوبة وبالحجم
+
+60
+00:04:29,390 --> 00:04:34,450
+المطلوب وبالعدد المطلوب. أضف إلى ذلك الـ potency of 
+
+61
+00:04:34,450 --> 00:04:39,690
+genital tract. كيف هي قدرة الـ genital tract في نقل
+
+62
+00:04:39,690 --> 00:04:43,090
+وفي إخراج الـ seminal fluid؟ هل تمشي وتسير بشكل
+
+63
+00:04:43,090 --> 00:04:47,790
+طبيعي أم هناك بعض المشاكل؟ أيضًا بيعطيني picture و
+
+64
+00:04:47,790 --> 00:04:52,410
+photo كاملة عن الـ secretory activity of the all
+
+65
+00:04:52,410 --> 00:04:54,370
+accessory gland. الـ accessory gland زي الـ
+
+66
+00:04:54,370 --> 00:04:58,110
+prostatic gland. كيف طبيعة عملها؟ هل تعمل بشكل سليم؟
+
+67
+00:04:58,280 --> 00:05:01,420
+تعمل بشكل دقيق، في عندها مشكلة، في عندي
+
+68
+00:05:01,420 --> 00:05:03,660
+deficiencies في الـ activity الخاصة فيها؟ أهمية 
+
+69
+00:05:03,660 --> 00:05:06,580
+normal في الـ normal status. The information 
+
+70
+00:05:06,580 --> 00:05:11,720
+contributes to the effective establishment of
+
+71
+00:05:11,720 --> 00:05:15,200
+individual diagnoses and serve as the essential 
+
+72
+00:05:15,200 --> 00:05:18,460
+basic investigation of male factors on the
+
+73
+00:05:18,460 --> 00:05:22,240
+infertile couple. فبالتالي، الـ seminal fluid يعتبر 
+
+74
+00:05:22,240 --> 00:05:26,180
+أول فحص يطلب في تشخيص الحالة الإنجابية أو القدرة
+
+75
+00:05:26,180 --> 00:05:30,950
+الإنجابية عند الرجل لأنه هيعطيني صورة عامة إلى حد ما
+
+76
+00:05:30,950 --> 00:05:37,230
+عن الوضع الحالي الذي يتمتع به الذكر بالنسبة للـ
+
+77
+00:05:37,230 --> 00:05:40,810
+Basic Seminal Analysis. بيلعب دور مهم جدا في الـ
+
+78
+00:05:40,810 --> 00:05:43,350
+Central... الـ Central role في الـ diagnostic of
+
+79
+00:05:43,350 --> 00:05:46,990
+male infertility. في الـ making significant 
+
+80
+00:05:46,990 --> 00:05:49,750
+contribution to the diagnosis process in 
+
+81
+00:05:49,750 --> 00:05:54,390
+andrology، gynecology، clinical urology. في ثلاثة
+
+82
+00:05:54,390 --> 00:05:57,970
+unit. هذه الـ unit الخاص بالـ clinical urology، الـ unit
+
+83
+00:05:57,970 --> 00:06:00,150
+الخاص بالـ andrology، الـ unit الخاص بالـ clinical الـ
+
+84
+00:06:00,150 --> 00:06:04,810
+clinic أو الـ unit الخاص بكينيكولوجيا. تولدت ثلاثة 
+
+85
+00:06:04,810 --> 00:06:08,710
+unit بيهتموا بالـ seminal analysis بالدرجة الأولى 
+
+86
+00:06:08,710 --> 00:06:14,470
+as basic analysis or basic test. في طبعا اختلاف ما
+
+87
+00:06:14,470 --> 00:06:17,650
+بين العلماء فعلى سبيل المثال في الأيام الحالية
+
+88
+00:06:17,650 --> 00:06:21,680
+الدراسات حكت أنه Examination include the analysis
+
+89
+00:06:21,680 --> 00:06:26,000
+of certain established seminal parameters can
+
+90
+00:06:26,000 --> 00:06:29,020
+provide key information about the quality of 
+
+91
+00:06:29,020 --> 00:06:33,880
+patient's semen and functional of sperm. بمعنى آخر
+
+92
+00:06:33,880 --> 00:06:37,620
+إن أنا بمجرد ما أحصل على تقرير له علاقة بالـ
+
+93
+00:06:37,620 --> 00:06:41,760
+Seminal Analysis بشكل صحيح ومضبوط أستطيع أن أحصل 
+
+94
+00:06:41,760 --> 00:06:45,800
+على صورة مبدئية عن الوضع الصحي والإنجابي الخاص 
+
+95
+00:06:45,800 --> 00:06:49,910
+بالمريض. وبناء عليه بقدر أشخص الحالة المرضية وبقدر 
+
+96
+00:06:49,910 --> 00:06:53,610
+أحدد في بعض طبيعة الفحوصات اللي أنا ممكن أطلبها
+
+97
+00:06:53,610 --> 00:06:57,990
+في المستقبل علشان يعملي correct or true diagnostic
+
+98
+00:06:57,990 --> 00:07:04,310
+or حاجة بنسميها تشخيص سليم، تشخيص صحيح 100%. This
+
+99
+00:07:04,310 --> 00:07:06,850
+information can help to determine reproductive
+
+100
+00:07:06,850 --> 00:07:11,630
+capacity of male. فبالتالي ممكن أنا من فقط الـ 
+
+101
+00:07:11,630 --> 00:07:14,910
+seminal fluid أو الـ seminal analysis أتعرف على 
+
+102
+00:07:14,910 --> 00:07:19,110
+الحالة الإنجابية. الـ WHO وهي اختصار للـ World 
+
+103
+00:07:19,110 --> 00:07:23,650
+Healthy Organization عملت دراسات وعملت reference
+
+104
+00:07:23,650 --> 00:07:28,090
+value للـ seminal fluid بمعنى قيم متعلقة بالـ
+
+105
+00:07:28,090 --> 00:07:32,010
+Fertile Men أو Fertile Males. ما هي الـ reference؟
+
+106
+00:07:32,010 --> 00:07:34,530
+يعني كم يجب أن تكون الـ utility؟ كم يجب أن تكون
+
+107
+00:07:34,530 --> 00:07:36,790
+الحركة؟ كم يجب أن تكون العدد؟ كم يجب أن تكون الـ
+
+108
+00:07:36,790 --> 00:07:39,430
+morphology؟ كم يجب أن تكون الـ volume؟ كم يجب أن
+
+109
+00:07:39,430 --> 00:07:44,580
+تكون الـ pH؟ هذا نسميه reference value. أيضا وجدوا
+
+110
+00:07:44,580 --> 00:07:49,300
+وصنعوا وكوّنوا وحضروا multi-step for manual
+
+111
+00:07:49,300 --> 00:07:54,280
+seminal analysis. كنت كـ تكنيشن، كـ أندرولوجيست، كيف
+
+112
+00:07:54,280 --> 00:07:57,580
+تستطيع عمل تحليل السائل؟ ما هي الخطوات المتبعة من
+
+113
+00:07:57,580 --> 00:08:03,560
+لحظة استلام العينة حتى كتابة التقرير؟ لكي نجمّل هذه
+
+114
+00:08:03,560 --> 00:08:08,760
+النقاط وهذه الخطوات قسموها إلى pre-analytical وهي 
+
+115
+00:08:08,760 --> 00:08:13,110
+خطواتنا قبل الفحص، analytical خطوات متعلقة بالفحص،
+
+116
+00:08:13,110 --> 00:08:18,130
+post-analytical خطوات ما بعد الفحص وهي التي تشمل 
+
+117
+00:08:18,130 --> 00:08:22,690
+في كتابة التقرير وتفسير النتائج. فبالتالي الـ 
+
+118
+00:08:22,690 --> 00:08:25,690
+Seminal بالوضع الطبيعي هو عبارة عن heterogeneous 
+
+119
+00:08:25,690 --> 00:08:31,530
+fluid بتكون من عدة مكونات مختلفة. هذه المكونات قد 
+
+120
+00:08:31,530 --> 00:08:36,650
+تتأثر بعوامل داخلية لها علاقة بالبيئة الداخلية
+
+121
+00:08:36,650 --> 00:08:41,870
+لجسد الإنسان أو جسد الذكر وطبيعة غذائه وعوامل 
+
+122
+00:08:41,870 --> 00:08:44,450
+خارجية اللي بتسميها environment factor أو
+
+123
+00:08:44,450 --> 00:08:48,870
+extrinsic factor. من أشهر العوامل التي قد تؤثر على 
+
+124
+00:08:48,870 --> 00:08:52,650
+الـ infertility أو على خليني أسميها بشكل أوضح على 
+
+125
+00:08:52,650 --> 00:08:57,150
+الـ seminal analysis الـ infection. هل وجود infection
+
+126
+00:08:57,150 --> 00:09:02,130
+في القنوات الناقلة أو في المصنع الـ accessory gland
+
+127
+00:09:02,130 --> 00:09:06,770
+function. كيف وظيفة هذه الغدد المساعدة؟ هل تقوم 
+
+128
+00:09:06,770 --> 00:09:11,330
+بالوظيفة المطلوبة ولا فيها انها inhibition. الـ
+
+129
+00:09:11,330 --> 00:09:14,870
+period of sexual absence، الفترة الامتناع عن الـ
+
+130
+00:09:14,870 --> 00:09:17,570
+ejaculation تلت أيام ولا أربع أيام ولا خمس أيام؟
+
+131
+00:09:17,570 --> 00:09:21,450
+خدوا بالكم، الفترة هذه مهمة جدا لأنه بناء عليها أنا
+
+132
+00:09:21,450 --> 00:09:26,410
+بقدر أقيم بشكل سليم وبشكل صحيح الـ value اللي بتطلع 
+
+133
+00:09:26,410 --> 00:09:31,090
+بعد تحليل السائل. أيضا من العوامل التي تؤثر 
+
+134
+00:09:31,090 --> 00:09:35,570
+anatomical، hormonal، Genetic، Life Style Factors. All
+
+135
+00:09:35,570 --> 00:09:39,450
+of these factors can contribute to male fertility.
+
+136
+00:09:39,450 --> 00:09:42,490
+خدوا بالكم، الهرمون عامل مهم زي ما شفنا في الشريحة
+
+137
+00:09:42,490 --> 00:09:45,910
+الرقم 2 هو المسؤول عن إنتاج الـ spermatocyte.
+
+138
+00:09:45,910 --> 00:09:50,450
+Life Style زي الـ smoking والكفين والـ stress عندك، 
+
+139
+00:09:50,450 --> 00:09:53,230
+الـ anatomical هنتكلم عنها زي ما اتكلمنا عنها عند
+
+140
+00:09:53,230 --> 00:09:58,650
+الـ female، و genetic بعض المشاكل الوراثية قد تؤدي 
+
+141
+00:09:58,650 --> 00:10:05,250
+إلى ال infertility عند ال male طبعاً هذا شكل بوضّح
+
+142
+00:10:05,250 --> 00:10:08,910
+و جدول بوضّح الـ Normal Value للـ Semen Parameter
+
+143
+00:10:08,910 --> 00:10:12,710
+الـ Liquefaction Time و هو وقت الإسالة تلاتين
+
+144
+00:10:12,710 --> 00:10:16,790
+minutes كحد أقصى الـ Ejaculate Volume و هو
+
+145
+00:10:16,790 --> 00:10:20,910
+الحجم المقضوف لازم يكون أكبر من أو يساوي
+
+146
+00:10:20,910 --> 00:10:26,050
+1.5 مل لتر عند الـ Normal من الـ Viscosity اللزوجة
+
+147
+00:10:26,050 --> 00:10:30,330
+لازم تعطيني Line خطّ بسمّيه و هنعرف إيش يعني Line
+
+148
+00:10:31,010 --> 00:10:35,510
+طوله أقل من أو يساوى 2 cm هي ال line اللي بتخرج من
+
+149
+00:10:35,510 --> 00:10:38,770
+ال pipet ال plastic pipet اللي هنتكلم عنها ال
+
+150
+00:10:38,770 --> 00:10:43,030
+total sperm count يجب أن يكون أكبر من أو يساوى 39
+
+151
+00:10:43,030 --> 00:10:46,990
+مليون ال sperm concentration لازم يكون أكبر من أو
+
+152
+00:10:46,990 --> 00:10:51,150
+يساوى 15 مليون ال total motility لازم يكون أكبر من
+
+153
+00:10:51,150 --> 00:10:58,020
+أو يساوى 40% أكبر من أو يساوى 32% الـ viability أو 
+
+154
+00:10:58,020 --> 00:11:01,220
+الـ life sperm لازم العينة تحتوي على أكثر من أو
+
+155
+00:11:01,220 --> 00:11:06,120
+يساوى 58% أما بالنسبة للـ normal form الشكل
+
+156
+00:11:06,120 --> 00:11:10,480
+الطبيعي للـ sperm يجب أن تحتوي العينة على أكثر من
+
+157
+00:11:10,480 --> 00:11:14,960
+40% من ال spermatocytes عفواً أكثر من 4% من ال
+
+158
+00:11:14,960 --> 00:11:19,500
+spermatocytes تكون normal form فبنلاحظ كل هذه ال
+
+159
+00:11:19,500 --> 00:11:24,310
+parameters مهمة هي في المنطق والمعقول مهمة ولكن أكثر
+
+160
+00:11:24,310 --> 00:11:28,790
+ما نهتم فيه إيجاد ال volume و ال sperm
+
+161
+00:11:28,790 --> 00:11:32,250
+concentration و ال total motility و المورفولوجي بس
+
+162
+00:11:32,250 --> 00:11:37,250
+في ال X المورفولوجي نسقط عنه أهم شيء ال motility و
+
+163
+00:11:37,250 --> 00:11:41,330
+ال concentration 
+
+164
+00:11:41,330 --> 00:11:46,930
+صورة توضّح ال step اللي احنا قسمناها pre analytical
+
+165
+00:11:46,930 --> 00:11:50,650
+و analytical و post analytical أول حاجة في عندي الـ
+
+166
+00:11:50,650 --> 00:11:55,410
+Sample Collection وهي مسئولية المريض بحدّ ذاته أولاً
+
+167
+00:11:55,410 --> 00:11:59,850
+وبدرجة أولى الـ Technician وظيفته الأساسية يعطي
+
+168
+00:11:59,850 --> 00:12:04,950
+الـ Container Strip ويقول له ويحكي له أهم التعليمات
+
+169
+00:12:04,950 --> 00:12:09,470
+اللازمة أثناء جمع العينة يعطيه بعض التوصيات من
+
+170
+00:12:09,470 --> 00:12:14,740
+خلالها بيقدر يوصل العينة بشكل سليم 100% ممكن تجمع
+
+171
+00:12:14,740 --> 00:12:17,980
+العينة في المكان، مكان إجراء الفحص أو في البيت بس
+
+172
+00:12:17,980 --> 00:12:21,620
+بشرط منطقة اللي هو فترة زمان يا دوبنا وصولها
+
+173
+00:12:21,620 --> 00:12:25,620
+للمختبر وجمعها في البيت لا تزيد عن نص ساعة أما
+
+174
+00:12:25,620 --> 00:12:29,320
+بالنسبة إلى عملية الـ Analysis وهي الـ Analytical
+
+175
+00:12:29,320 --> 00:12:33,820
+تقسم إلى قسمين Macro و Micro الـ Macro أي شيء أنا
+
+176
+00:12:33,820 --> 00:12:38,900
+بشوفه بالعين المجردة زي Liquefaction Time Sample Age
+
+177
+00:12:38,900 --> 00:12:43,180
+يعني جمعت من ساعة، من ساعة ونصف الـ Appearance، الـ
+
+178
+00:12:43,180 --> 00:12:47,440
+Volume، الـ Viscosity و الـ pH هذه تقسيم الـ Macro أما
+
+179
+00:12:47,440 --> 00:12:50,820
+ال Micro زي ال motility، ال concentration، ال
+
+180
+00:12:50,820 --> 00:12:56,020
+morphology، ال agglutination في بعض المصطلحات وبعض
+
+181
+00:12:56,020 --> 00:12:59,680
+الأطباء خلّيني أسمّيها وبعض المصطلحات الطبية التي
+
+182
+00:12:59,680 --> 00:13:05,760
+تستخدم وتُطلب من قبل أطباء كفحوصات مساعدة ولكنها
+
+183
+00:13:05,760 --> 00:13:11,840
+أساسية تحت عنوان Helping test أو خلّيني أسمّيها 
+
+184
+00:13:11,840 --> 00:13:15,140
+اوكي من أشهرها ال fructose نقص نسبة ال fructose
+
+185
+00:13:15,140 --> 00:13:18,900
+في السائل المنوي و ال sperm و ال viability جداش
+
+186
+00:13:18,900 --> 00:13:23,940
+عدد ال life sperm مهم جداً خصوصاً أثناء عملية الإلاج
+
+187
+00:13:23,940 --> 00:13:30,020
+هذه أشهر المصطلحات اللي احنا هنواجهها خلال عملية
+
+188
+00:13:30,020 --> 00:13:35,740
+ال seminal analysis طبعاً عملية جمع العينة بشكل
+
+189
+00:13:35,740 --> 00:13:39,960
+أساسي تعتبر هي الـ critical step بمعنى آخر لو جمعت
+
+190
+00:13:39,960 --> 00:13:43,660
+العينة بطريقة غير سليمة فالنتيجة تلقائياً غير سليمة
+
+191
+00:13:43,660 --> 00:13:47,540
+وغير صحيحة فيجب أن تجمع العينة بطريقة سليمة طريقة
+
+192
+00:13:47,540 --> 00:13:52,640
+صحيحة 100% لكي تؤدي إلى إنتاج نتيجة سليمة وللعملية
+
+193
+00:13:52,640 --> 00:13:57,100
+الـ sample collection مسئولية المريض بحدّ ذاته وبحدّ
+
+194
+00:13:57,100 --> 00:14:01,400
+ودرجة أولى ولكن if liquefaction does not occur
+
+195
+00:14:01,400 --> 00:14:04,360
+probably the physical and chemical properties of
+
+196
+00:14:04,360 --> 00:14:10,340
+the seminal may be wrong or have a problem بمعنى
+
+197
+00:14:10,340 --> 00:14:14,300
+آخر، العينة المرسلة للمختبر لازم تصلها إسالة بشكل
+
+198
+00:14:14,300 --> 00:14:18,220
+سليم وصحيح إذا صارت لها إسالة بشكل غير سليم وغير
+
+199
+00:14:18,220 --> 00:14:22,720
+صحيح، النتيجة تعتبر غير دقيقة من أهم الـ Adjacent
+
+200
+00:14:22,720 --> 00:14:25,340
+Test أو الـ Helping Test اللي احنا حكينا فيها الـ
+
+201
+00:14:25,340 --> 00:14:28,820
+viability الـ lycoside الـ concentration of
+
+202
+00:14:28,820 --> 00:14:33,560
+fructose الـ concentration of fructose for example
+
+203
+00:14:33,560 --> 00:14:38,080
+هذه الـ most common الفحوصات التي يمكن أن تُستخدم و
+
+204
+00:14:38,080 --> 00:14:42,940
+تُطلب من قبل الطبيب للمساعدة في تشخيص المرض Sample
+
+205
+00:14:42,940 --> 00:14:47,120
+Collection تُجمع العينة في container استلاءة استرايه
+
+206
+00:14:47,120 --> 00:14:50,240
+container with wide mouth مايعني wide mouth؟ يعني
+
+207
+00:14:50,240 --> 00:14:54,200
+فتحة ال container تكون واسعة ليس منطقي تجمع في ال
+
+208
+00:14:54,200 --> 00:14:58,460
+test tube على سبيل المثال لازم تجمع في cup يشبه ال
+
+209
+00:14:58,460 --> 00:15:02,820
+urine cup ولكن استرالي دايمًا بكون cover red color
+
+210
+00:15:02,820 --> 00:15:07,620
+زي على سبيل المثال ال cup اللي يُستخدم فيه ال urine
+
+211
+00:15:07,620 --> 00:15:15,560
+culture طبعاً ممنوع أنا ك technician لازم عليّ أنه
+
+212
+00:15:15,560 --> 00:15:20,080
+أقول للمريض أنه يجب أن يمتنع عن جمع العينة باستخدام
+
+213
+00:15:20,080 --> 00:15:24,200
+ال apricot أو ال condom لأن كلاهما فيه مواد قاتلة لل
+
+214
+00:15:24,200 --> 00:15:30,580
+sperm حاجة بتسمّيها spermicidal agent تُجمع
+
+215
+00:15:30,580 --> 00:15:33,600
+العينة بطريقة واحدة وأفضل الطرق على الإطلاق هي
+
+216
+00:15:33,600 --> 00:15:37,840
+طريقة ال masterbation طريقة تُتّبع في مراكز
+
+217
+00:15:37,840 --> 00:15:42,740
+التلقيح الصناعي العينة جميعها يجب أن تُجمع في ال
+
+218
+00:15:42,740 --> 00:15:45,960
+container أي قدر للعينة يجب أن يُبلغ به ال
+
+219
+00:15:45,960 --> 00:15:49,560
+technician يعني بمعنى آخر المفروض يعمل ejaculation
+
+220
+00:15:49,560 --> 00:15:54,850
+لخمسة مل تم جمع أربعة مل إذا بكتب خمسة أربعة ملخمسة
+
+221
+00:15:54,850 --> 00:15:58,970
+ml collected قسمين أربعة ml received و one ml
+
+222
+00:15:58,970 --> 00:16:08,010
+مفقد ال time of collection مهم جداً لو أنا كمريض
+
+223
+00:16:08,010 --> 00:16:11,510
+جمعت العينة في المختبر لازم أبلغ التكنيشن بالوقت
+
+224
+00:16:11,510 --> 00:16:15,530
+اللي جمعت فيه العينة لو كمريض جمعت العينة في البيت
+
+225
+00:16:15,530 --> 00:16:18,930
+لازم أبلغ التكنيشن بالوقت اللي جمعت فيه العينة
+
+226
+00:16:18,930 --> 00:16:23,050
+سواء كان في البيت أو في المختبر عشان بناء عليه لازم
+
+227
+00:16:23,050 --> 00:16:28,130
+يحسب الـ liquefaction ال sample collection بمجرد
+
+228
+00:16:28,130 --> 00:16:30,550
+ما أحصل عليها لازم أكتب كل البيانات على ال
+
+229
+00:16:30,550 --> 00:16:34,390
+container وأدخلها في ال incubator على 37 درجة
+
+230
+00:16:34,390 --> 00:16:38,790
+موية من أجل ال liquefaction ثم أبدأ فيما بعد بال
+
+231
+00:16:38,790 --> 00:16:43,930
+macroscopic analysis اللي لازم يتم خلال فترة زمنية
+
+232
+00:16:43,930 --> 00:16:48,200
+من نصفها إلى ساعة، 60 دقيقة خلال هذه الفترة الزمنية
+
+233
+00:16:48,200 --> 00:16:52,500
+لازم كل ال macroscopic examination أو analysis
+
+234
+00:16:52,500 --> 00:16:58,640
+تكون انتهيت منها بشكل كامل زي ال viscosity زي ال pH
+
+235
+00:16:58,640 --> 00:17:04,000
+زي ال color زي ال volume وخلافه The most important
+
+236
+00:17:04,000 --> 00:17:06,980
+issue of the sample collection is the abstinence time
+
+237
+00:17:06,980 --> 00:17:10,880
+the number of days without ejaculation مهم جداً
+
+238
+00:17:10,880 --> 00:17:15,830
+بشكل كبير جداً أنه تُجمع العينة بعد امتناع عن ال
+
+239
+00:17:15,830 --> 00:17:19,270
+ejaculation أو عن ال intercourse بفترة زمنية معينة
+
+240
+00:17:19,270 --> 00:17:24,570
+أقلها تلات أيام، أكثرها خمس أيام ولكن معظم المراكز
+
+241
+00:17:24,570 --> 00:17:27,410
+تستعمل أن يجب على المريض الامتناع عن ال
+
+242
+00:17:27,410 --> 00:17:31,430
+ejaculation أو ال intercourse تلات أيام بشكل أساسي
+
+243
+00:17:31,430 --> 00:17:34,970
+في اليوم التالت بيجمع العينة في نهاية اليوم التالت
+
+244
+00:17:34,970 --> 00:17:38,340
+أو بعض الأحيان بيقول لك في بداية اليوم الرابع المهم
+
+245
+00:17:38,340 --> 00:17:41,820
+يكون له تلات أيام ممتنع before sample collection
+
+246
+00:17:41,820 --> 00:17:44,840
+spermatozoa are stored in the epididymis until
+
+247
+00:17:44,840 --> 00:17:50,180
+ejaculation however, the epididymal storage is not
+
+248
+00:17:50,180 --> 00:17:53,200
+completely empty in a single ejaculation and the
+
+249
+00:17:53,200 --> 00:17:56,240
+remaining spermatozoa stay until the next
+
+250
+00:17:56,240 --> 00:18:00,560
+ejaculation كون على ثقة أن صحيح أن ال spermatozoa
+
+251
+00:18:00,560 --> 00:18:04,920
+تُخزن في ال epididymis ولكن خلال ال ejaculation اللي
+
+252
+00:18:04,920 --> 00:18:08,860
+بيعطيها الـ 105 أو 3 أو 4 ml ما بيطلع كل المخزون
+
+253
+00:18:08,860 --> 00:18:14,920
+جزء منه يبقى لـ Ejaculation التالية علشان كده مهم
+
+254
+00:18:14,920 --> 00:18:21,180
+جداً أكون هذه المعلومة في نص عيني وأبقى على دراية
+
+255
+00:18:21,180 --> 00:18:26,420
+فيها علشان أقدر أقيم بشكل سليم Ideal duration of
+
+256
+00:18:26,420 --> 00:18:32,120
+sexual absence 2 to 3 days و لكن الكل متّفق على تلات
+
+257
+00:18:32,120 --> 00:18:35,100
+أيام معظمهم متّفق على تلات أيام يجب على المريض اللي
+
+258
+00:18:35,100 --> 00:18:39,460
+مدينة عنه ejaculation أو ال intercourse تلات أيام
+
+259
+00:18:39,460 --> 00:18:45,320
+طيب لو أنا بدي أعمل تحليل آخر كقبل طلب تحليل آخر
+
+260
+00:18:45,320 --> 00:18:50,100
+المريض يجمع العينة مباشرة ولا ينتظر فترة لازم
+
+261
+00:18:50,100 --> 00:18:55,060
+المريض ينتظر فترة أقلها أسبوعين يعني التحليل الأول
+
+262
+00:18:55,060 --> 00:18:58,280
+كان في واحد عشرة التحليل الثاني لازم يكون في أربع
+
+263
+00:18:58,280 --> 00:19:02,770
+عشر  يعني بمعنى آخر بين التحليل الأول والثاني
+
+264
+00:19:02,770 --> 00:19:08,870
+أسبوعين هي نقطة تُجمع بنفس الطريقة هي نقطتين تُجمع
+
+265
+00:19:08,870 --> 00:19:12,470
+بنفس ال absence of intercourse أو ال sexual
+
+266
+00:19:12,470 --> 00:19:15,110
+absence في المرة الأولى امتنع يومين في المرة
+
+267
+00:19:15,110 --> 00:19:17,490
+الثانية لازم يمتنع يومين في المرة الأولى امتنع
+
+268
+00:19:17,490 --> 00:19:20,670
+تلاتة في المرة الثانية لازم يمتنع تلات أيام علشان
+
+269
+00:19:20,670 --> 00:19:25,210
+يصير في عندي نوع من أنواع ال bias نتجنبه نتجنب الـ
+
+270
+00:19:25,210 --> 00:19:28,730
+bias أو الـ interfere اللي ممكن تصير ال interval
+
+271
+00:19:28,730 --> 00:19:31,350
+between separated  samples من ال analysis is generally
+
+272
+00:19:31,350 --> 00:19:36,070
+recommended to be two to four weeks ولكن الكل متّفق
+
+273
+00:19:36,070 --> 00:19:40,190
+أنه أقل شيء أسبوعين فبالتالي أسبوعين وأيام ما ينفع
+
+274
+00:19:40,190 --> 00:19:43,750
+معك من أسبوعين لأربع أسابيع كمريض ولكن الكل متّفق
+
+275
+00:19:43,750 --> 00:19:46,650
+زي ما هو متّفق على تلات أيام sexual absence الكل
+
+276
+00:19:46,650 --> 00:19:51,490
+متّفق على تلات أسابيع ما بين العينة الأولى والعينة
+
+277
+00:19:51,490 --> 00:19:52,670
+التالية
+
+278
+00:19:54,630 --> 00:19:58,050
+نبدأ بأول نقطة تتعلق بالـ macroscopic
+
+279
+00:19:58,050 --> 00:20:00,970
+evaluation كيف يمكن تحديد الـ macroscopic
+
+280
+00:20:00,970 --> 00:20:03,970
+evaluation؟ بمعنى آخر، هل يمكن تحديد الـ 
+
+281
+00:20:03,970 --> 00:20:07,770
+macroscopic evaluation؟ وما هي؟ أول test له علاقة 
+
+282
+00:20:07,770 --> 00:20:10,970
+بالـ macroscopic الـ liquefication، وهي الإسالة
+
+283
+00:20:10,970 --> 00:20:17,850
+الإسالة هي تحول الـ seminal fluid من شكل الكتل إلى 
+
+284
+00:20:17,850 --> 00:20:21,490
+شكل liquid من الشكل الـ semisolid إلى شكل الـ
+
+285
+00:20:21,490 --> 00:20:21,650
+liquid
+
+286
+00:20:26,220 --> 00:20:31,500
+الـ Semen بيخرج على شكل دفقات هي عبارة محاطة بكمية
+
+287
+00:20:31,500 --> 00:20:35,700
+من البروتين لتحميه من ال external environment أو
+
+288
+00:20:35,700 --> 00:20:40,040
+external factor بالإضافة إلى ال environment
+
+289
+00:20:40,040 --> 00:20:43,100
+المختلفة الموجودة في ال reproductive tract الخاصة
+
+290
+00:20:43,100 --> 00:20:47,320
+بالفيميل فبالتالي after ejaculation human semen
+
+291
+00:20:47,320 --> 00:20:51,600
+forms lose gel-like coagulant in a few seconds by
+
+292
+00:20:51,600 --> 00:20:55,790
+cross-linking of seminal vesicle protein لذّن السمنة
+
+293
+00:20:55,790 --> 00:20:59,170
+الـ fluid بمجرد خروجه من جسم الإنسان بيتحول من
+
+294
+00:20:59,170 --> 00:21:02,430
+القوام الجيلاتيني الجلي إلى القوام السائل بفعل 
+
+295
+00:21:02,430 --> 00:21:05,810
+إنزيمات وبروتينات موجودة في السمنة الـ fluid من
+
+296
+00:21:05,810 --> 00:21:11,450
+أهمها الـ سينوكليين 1 و 2 والفيبرينوكتين as 
+
+297
+00:21:11,450 --> 00:21:17,170
+proteins the formation of coagulant مهم جدا، ماهو
+
+298
+00:21:17,170 --> 00:21:20,150
+هدف الـ coagulant؟ ماهو هدف المادة الجيلاتينية
+
+299
+00:21:20,150 --> 00:21:26,370
+التي تحيط بالسمنة بال spermatozoa أو بـ sperm حكينا
+
+300
+00:21:26,370 --> 00:21:32,530
+أول شغلة بتعمل على تقليل معدل خروج السمن الفلود من
+
+301
+00:21:32,530 --> 00:21:36,150
+من منطقة الفاجينة فهذا بيزيد من فرصة ال fertilization
+
+302
+00:21:36,150 --> 00:21:39,910
+to minimize the backflow يعني التطفق للخارج أو
+
+303
+00:21:39,910 --> 00:21:44,810
+للخلف بعد التبويض في الفاجينة نقطة تانية to
+
+304
+00:21:44,810 --> 00:21:50,850
+protect the spermatozoa or sperm from the acidic
+
+305
+00:21:50,850 --> 00:21:55,170
+pH of vagina and to protect them from immune attack
+
+306
+00:21:55,170 --> 00:21:59,670
+يعني تلت أسباب ووظائف للـ coagulant المادة
+
+307
+00:21:59,670 --> 00:22:02,590
+الجيلاتينية التي تحيط بالـ sperm حماية من الـ 
+
+308
+00:22:02,590 --> 00:22:05,450
+acidic pH الموجودة في الفاجينة حماية من ال immune
+
+309
+00:22:05,450 --> 00:22:09,390
+system attack أو الimmune attack ومنع ال back
+
+310
+00:22:09,390 --> 00:22:15,050
+flow بعد التبويض اللي بيصير في الفاجينة مادة
+
+311
+00:22:15,050 --> 00:22:17,650
+أخرى موجودة في الـ seminal fluid وتساعد على
+
+312
+00:22:17,650 --> 00:22:22,090
+الليكوفيكاشن هي البروستاتا specific antigen بقعة
+
+313
+00:22:22,090 --> 00:22:25,950
+اللي عاوز أسموها البروستاتيك specific antigen ABCA
+
+314
+00:22:25,950 --> 00:22:30,510
+هذه تلعب
+
+315
+00:22:30,510 --> 00:22:35,390
+دور كبير جدا ومهم في تكسير الكواكولوم علشان تعمل
+
+316
+00:22:35,390 --> 00:22:41,730
+تحرير للسبيرماتوزوة مصدرها بشكل أساسي لبروستاتا في
+
+317
+00:22:41,730 --> 00:22:46,010
+أيضا مادة أخرى الـ Vibrinolysis Vibrinolysis هو
+
+318
+00:22:46,010 --> 00:22:50,570
+عبارة عن بروتاليتك إنزين يفرز أيضًا من البرستاتا
+
+319
+00:22:50,570 --> 00:22:54,290
+وبيلعب دور مهم جدًا في تكسير الفيبرين المسؤول عن
+
+320
+00:22:54,290 --> 00:22:58,870
+تكوين الـ coagulant which liquefies the seminal
+
+321
+00:22:58,870 --> 00:23:01,790
+fluid within fifty to thirty minutes the function of
+
+322
+00:23:01,790 --> 00:23:05,790
+this enzyme is gradual طبعًا البرستاتك ال specific
+
+323
+00:23:05,790 --> 00:23:08,330
+انتجن أو البرستاتك ال specific antigen و ال
+
+324
+00:23:08,330 --> 00:23:12,670
+Vibrinolysis ال Vibrinolysin as enzyme ما بيشتغلوا 
+
+325
+00:23:12,670 --> 00:23:18,610
+بشكل مفاجئ، لأ بشكل تدريجي ما بيقطع منطقة الـ
+
+326
+00:23:18,610 --> 00:23:21,890
+cervical إلا بيكون صارله complete liquefaction هذا
+
+327
+00:23:21,890 --> 00:23:25,890
+بالوضع الطبيعي، عشان كده بتاخد من 15 أقل شيء إلى
+
+328
+00:23:25,890 --> 00:23:30,590
+30 الـ liquefaction كان okay رأي رومتون بريتشار
+
+329
+00:23:30,880 --> 00:23:36,280
+ويمكننا إستعمال ذلك باستخدام مخزن لدرجة 37 دقائق
+
+330
+00:23:36,280 --> 00:23:37,960
+مستمر في المزيد من المزيد من المزيد من المزيد من
+
+331
+00:23:37,960 --> 00:23:40,380
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+332
+00:23:40,380 --> 00:23:40,820
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+333
+00:23:40,820 --> 00:23:47,520
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+334
+00:23:47,520 --> 00:23:51,480
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+335
+00:23:51,480 --> 00:23:51,500
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+336
+00:23:51,500 --> 00:23:58,010
+المزيد من المزيد من المزيد من المزيد الprocess of
+
+337
+00:23:58,010 --> 00:24:01,050
+liquefaction is significant as it allows for
+
+338
+00:24:01,050 --> 00:24:04,410
+immobilized sperm to become motile مهم جدا عشان تسمح
+
+339
+00:24:04,410 --> 00:24:07,790
+للـ spermatozoa أنها تتحرك، ما تكون عالقة داخل
+
+340
+00:24:07,790 --> 00:24:12,110
+الشبكة، if the semen fails to liquefy it, it can
+
+341
+00:24:12,110 --> 00:24:17,670
+be indicative of a glandular dysfunction of the
+
+342
+00:24:17,670 --> 00:24:20,750
+prostata والله بعد نص ساعة ما أصلحش liquefaction
+
+343
+00:24:20,750 --> 00:24:24,780
+لعينة، استنيت كمان 35، كمان 5 دقايق خمس و تلاتين،
+
+344
+00:24:24,780 --> 00:24:27,440
+اربعين، خمس و اربعين، خمسين ما صارش liquefaction
+
+345
+00:24:27,440 --> 00:24:30,820
+إذا أنا بعرف إن فيه أنا عندي مشكلة في البروستاتا
+
+346
+00:24:30,820 --> 00:24:33,720
+لإن هي اللي بتفرز البروستاتا ال specific antigen و
+
+347
+00:24:33,720 --> 00:24:37,760
+ال fibrinolysis أو fibrinolysin as a proteolytic
+
+348
+00:24:37,760 --> 00:24:40,720
+enzyme معناه في عندي dysfunction اللي فيه
+
+349
+00:24:40,720 --> 00:24:45,020
+البروستاتا ال abnormality الخاصة بال liquefication
+
+350
+00:24:45,020 --> 00:24:49,360
+أسبابها عندي ejaculatory duct obstruction في عندي
+
+351
+00:24:49,360 --> 00:24:51,400
+obstruction في ال ejaculatory duct في القضايا
+
+352
+00:24:51,400 --> 00:24:56,070
+القادرة فيها اندى congenital absence للسمن physical
+
+353
+00:24:56,070 --> 00:25:00,690
+الناقل أو فيها اندى genital tract infection وهي
+
+354
+00:25:00,690 --> 00:25:06,370
+تعتبر من أكثر الأسباب شيوعا لحدوث elongation in
+
+355
+00:25:06,370 --> 00:25:09,850
+the duration of .. in the duration time of السمن
+
+356
+00:25:09,850 --> 00:25:13,670
+liquification يعني زيادة أكثر الأسباب انتشارا
+
+357
+00:25:13,670 --> 00:25:19,230
+والتي تؤدي إلى زيادة الوقت المستهلك لتميُع السائل
+
+358
+00:25:19,230 --> 00:25:25,630
+هي عبارة عن ال genital tract infection النوع التاني
+
+359
+00:25:25,630 --> 00:25:28,850
+أو ال test التاني من ال macroscopic هي عبارة عن ال
+
+360
+00:25:28,850 --> 00:25:32,910
+viscosity اللزوجة طبعا after liquefaction تصل
+
+361
+00:25:32,910 --> 00:25:36,210
+liquification بعد نص ساعة كل الفحوصات مباحة يعني
+
+362
+00:25:36,210 --> 00:25:39,450
+ممكن أنت تستطيع أن تعمل أي فحص بعد ال
+
+363
+00:25:39,450 --> 00:25:41,930
+liquification قبل ال liquefification ممنوع تعمل أي
+
+364
+00:25:41,930 --> 00:25:46,050
+فحص حتى لو كان فحص بسيط جدا ال viscosity referred
+
+365
+00:25:46,050 --> 00:25:49,390
+to elastic properties of the sample after
+
+366
+00:25:49,390 --> 00:25:53,110
+liquefaction يعني أنا بشوف ميعدتها كيف؟ بشوف 
+
+367
+00:25:53,110 --> 00:25:56,700
+لزوجتها كيف؟ بشوف قوامها كيف، قوام مين؟ قوام العينة
+
+368
+00:25:56,700 --> 00:25:59,380
+اللي عبارة عن السمن طب كيف بتعملها عملية
+
+369
+00:25:59,380 --> 00:26:02,740
+evaluation ببساطة جدا بجيب dropper، plastic
+
+370
+00:26:02,740 --> 00:26:07,060
+dropper، استراعي بعمل mixing و باخد العينة كلها و
+
+371
+00:26:07,060 --> 00:26:11,780
+برفع إيدي و بعمل dropping بشوف السمن ال fluid بنزل
+
+372
+00:26:11,780 --> 00:26:15,840
+قطرة قطرة ولا بنزل على هذه ال line و ال line اللي
+
+373
+00:26:15,840 --> 00:26:19,240
+بنزل جدش تورو تقديرا، مش بجيب مصدر وقيص، لأ تقديرا
+
+374
+00:26:19,240 --> 00:26:23,960
+فإذا كانت بنزل drop by drop معناه انه liquification
+
+375
+00:26:23,960 --> 00:26:29,020
+طبيعية و الviscosity طبيعية والله نزل على شكل ال
+
+376
+00:26:29,020 --> 00:26:33,300
+line طوله 2 cm تقريبا إذا بسميها hyperviscosity من
+
+377
+00:26:33,300 --> 00:26:37,220
+2 إلى 4 slightly hyperviscosity من 4 إلى 6
+
+378
+00:26:37,220 --> 00:26:42,500
+moderate hyperviscosity أكتر من 6 cm معناها higher
+
+379
+00:26:42,500 --> 00:26:48,380
+hyperviscosity هذه فكرة الviscosity معظمه يكون ما
+
+380
+00:26:48,380 --> 00:26:52,830
+بين hyper و slightly ولكن في ناس بتكون normal drop
+
+381
+00:26:52,830 --> 00:26:57,710
+by drop الـ abnormal viscosity وجدوا أنها لها
+
+382
+00:26:57,710 --> 00:27:03,030
+علاقة بأمر معين وهو hypofunction of prostata or
+
+383
+00:27:03,030 --> 00:27:06,450
+seminal vesicle يعني عندي reduction في الـ
+
+384
+00:27:06,450 --> 00:27:10,530
+functional المتعلقة بالبرستاتكي gland و ال seminal
+
+385
+00:27:10,530 --> 00:27:14,610
+vesicle علما عندي مشكلة في ال functional إذا كلا
+
+386
+00:27:14,610 --> 00:27:16,790
+المنطقتين سواء كانت البرستاتا أو ال seminal
+
+387
+00:27:16,790 --> 00:27:21,180
+vesicle لن تستطيع إخراج محتوىها فبالتالي، هيكون
+
+388
+00:27:21,180 --> 00:27:23,360
+عندي مشكلة في الـ liquefication ومشكلة في
+
+389
+00:27:23,360 --> 00:27:26,460
+الviscosity on the other hand, infection and
+
+390
+00:27:26,460 --> 00:27:30,100
+inflammation of accessory gland or other male
+
+391
+00:27:30,100 --> 00:27:32,860
+fertility related disease may also lead to semen
+
+392
+00:27:32,860 --> 00:27:36,800
+hyperviscosity in men with functionally normal
+
+393
+00:27:36,800 --> 00:27:40,760
+accessory gland في بعض الأحيان، ممكن يكون عندي ال
+
+394
+00:27:40,760 --> 00:27:44,680
+functional gland normal 100% ولكن في مشكلة عندي في
+
+395
+00:27:44,680 --> 00:27:47,720
+الviscosity بيكون سببها infection أو inflammation
+
+396
+00:27:47,720 --> 00:27:51,900
+في ال accessary gland فممكن أنا أطلق عليها و
+
+397
+00:27:51,900 --> 00:27:55,640
+أشخصها عفوا من خلال اعمل مظرة على ال seminal fluid
+
+398
+00:27:55,640 --> 00:27:59,860
+زي ما بعمل مظرة على ال urine بعمل مظرة على ال
+
+399
+00:27:59,860 --> 00:28:04,680
+seminal fluid ال hyperviscosity has been shown to
+
+400
+00:28:04,680 --> 00:28:07,980
+be ايش ال hyperviscosity أسبابها what is the
+
+401
+00:28:07,980 --> 00:28:11,460
+reasons of hyperviscosity أول حاجة وجدوا انها
+
+402
+00:28:11,460 --> 00:28:17,790
+associated with a lower percentage of motility spermatozoa بمعنى آخر
+
+403
+00:28:17,790 --> 00:28:20,890
+خلّيني أسميها رغم إن عرفنا في النقطة الأولى
+
+404
+00:28:20,890 --> 00:28:25,530
+أسبابها زي الـ Hypofunctional Prostatic أو الـ
+
+405
+00:28:25,530 --> 00:28:27,750
+Hypofunctional Seminal Vesicle أو عنده
+
+406
+00:28:27,750 --> 00:28:30,890
+Inflammation أو Infection طب الـ Hyperfiscosity
+
+407
+00:28:30,890 --> 00:28:36,350
+لإيش تؤدي؟ إيش مخاطرها؟ إيش الـ side effect تبعها؟
+
+408
+00:28:36,350 --> 00:28:40,460
+الـ side effect أول حاجة بتعملي lower أو الـ
+
+409
+00:28:40,460 --> 00:28:43,580
+reduction in the percentage of motile sperm نسبة
+
+410
+00:28:43,580 --> 00:28:46,060
+الـ motile sperm بتكون قليلة جدا لإن ال sperm
+
+411
+00:28:46,060 --> 00:28:52,020
+بيكون محصور داخل شبكة اتنين indicative of a
+
+412
+00:28:52,020 --> 00:28:54,700
+deficiency in the functional activity of accessory
+
+413
+00:28:54,700 --> 00:28:58,340
+sex glands لما تكون ال viscosity عالية معناه أنه أنا
+
+414
+00:28:58,340 --> 00:29:02,760
+عندي مشكلة في وظائف الغدد الجنسية أو الغدد المساعدة
+
+415
+00:29:02,760 --> 00:29:08,520
+ل ال reproductive system عند المن نجلد نوع تالت من
+
+416
+00:29:08,520 --> 00:29:14,010
+أنواع الـ Macroscopic Examination و هو الـ pH طبعا
+
+417
+00:29:14,010 --> 00:29:18,170
+في عندي accessor gland أو accessory sex gland هي التي
+
+418
+00:29:18,170 --> 00:29:23,930
+تساهم في إنتاج الـ pH الخاص بالـ seminal fluid على
+
+419
+00:29:23,930 --> 00:29:28,070
+سبيل المثال الـ seminal is multiglandular in
+
+420
+00:29:28,070 --> 00:29:31,050
+origin with the acidic prostata and alkaline
+
+421
+00:29:31,050 --> 00:29:36,330
+seminal vesicle يعني الـ prostate بتفرز fluid acid و
+
+422
+00:29:36,330 --> 00:29:37,950
+الـ seminal vesicle بتفرز
+
+423
+00:29:41,680 --> 00:29:46,440
+مين بتغير تاني بيديني تكوين الـ pH الخاص بالـ semen
+
+424
+00:29:46,440 --> 00:29:51,440
+وهو high pH يعني إيش يعني high pH؟ يعني أكبر من 7
+
+425
+00:29:51,440 --> 00:29:56,340
+يعني alkaline combining to produce alkaline fluid
+
+426
+00:29:56,340 --> 00:30:01,200
+with the high pH range from 7.2 ل 8 إذا أخذنا
+
+427
+00:30:01,200 --> 00:30:04,720
+بالكم هنا من النقطة صحيح إنه في عندك بروستاتا
+
+428
+00:30:04,720 --> 00:30:08,660
+بتفرز acidic fluid وصحيح عندك في seminal physically
+
+429
+00:30:08,660 --> 00:30:12,420
+بتفرز alkaline fluid والاتنين الـ fluid يلتقوا في
+
+430
+00:30:12,420 --> 00:30:16,840
+مجلة واحد وهو الـ ejaculatory duct ولكن الـ pH تبع
+
+431
+00:30:16,840 --> 00:30:20,240
+الـ seminal physical يطغى على الـ pH تبع ال
+
+432
+00:30:20,240 --> 00:30:23,440
+prostatic لأن كمية الـ fluid اللي جاي من الـ seminal
+
+433
+00:30:23,440 --> 00:30:27,660
+physical أعلى فبالتالي بيعطي الـ pH الـ alkaline
+
+434
+00:30:27,660 --> 00:30:32,920
+الخاص بالـ seminal fluid الـ pH اللي له عبارة من 7
+
+435
+00:30:32,920 --> 00:30:41,720
+.2 ل 8 الـ pH إذا كان أقل من 7 بكون أسبابها أو تقنين
+
+436
+00:30:41,720 --> 00:30:45,740
+مؤشر أنه في congenital absent في الـ vas deferens
+
+437
+00:30:45,740 --> 00:30:49,680
+أو obstruction في الـ ejaculatory duct يعني لما اجى
+
+438
+00:30:49,680 --> 00:30:52,960
+الـ pH على طريق الـ stream أقل من 7 نقول من الـ fluid
+
+439
+00:30:52,960 --> 00:30:57,580
+بقول والله ممكن يكون absent في الـ congenital أو
+
+440
+00:30:57,580 --> 00:31:00,420
+يعني بمعنى absent في الـ vas deferens وهذا طبيعة ال
+
+441
+00:31:00,420 --> 00:31:03,840
+absent congenital يعني الذكر هذا مولود بالـ absent
+
+442
+00:31:03,840 --> 00:31:08,400
+منذ الولادة أو في عندي انسداد في الـ ejaculatory
+
+443
+00:31:08,400 --> 00:31:15,620
+duct القناة القادفة لو زاد الـ pH عن 7.8 أو زاد عن 8
+
+444
+00:31:15,620 --> 00:31:19,620
+صار more alkaline أسبابها أو بيعطيني indication
+
+445
+00:31:19,620 --> 00:31:22,120
+أنه والله عندي فيه مشكلة في الـ seminal vesicle
+
+446
+00:31:22,120 --> 00:31:25,560
+حاجة بنسميها dysfunctional seminal vesicle
+
+447
+00:31:25,560 --> 00:31:30,260
+dysfunctional seminal vesicle إذن الـ normal range
+
+448
+00:31:30,260 --> 00:31:34,340
+عرفناه للـ pH للـ seminal fluid إن زاد الـ pH وإن قل
+
+449
+00:31:34,340 --> 00:31:38,940
+الـ pH بيعتبر indicative و indication على شو بالضبط
+
+450
+00:31:40,780 --> 00:31:44,220
+كذا بيكون خلصنا الـ microscopic التي تورا بالعين
+
+451
+00:31:44,220 --> 00:31:48,680
+المجردة سنتنتقل إلى موضوع جديد له علاقة بال
+
+452
+00:31:48,680 --> 00:31:53,740
+microscopic examination وهذا الكلام إن شاء الله
+
+453
+00:31:53,740 --> 00:32:00,640
+هنمشي فيه بخطة على أمل إنه نبسط بعض النقاط ال
+
+454
+00:32:00,640 --> 00:32:04,140
+microscopic examination أول مصطلح اللي بنحكي فيه و
+
+455
+00:32:04,140 --> 00:32:08,940
+هو أهم مصطلح هو الـ sperm concentration خدوا بالكم
+
+456
+00:32:08,940 --> 00:32:14,200
+keep in your mind There are two terms sperm
+
+457
+00:32:14,200 --> 00:32:18,460
+concentration and total sperm count دولة different
+
+458
+00:32:18,460 --> 00:32:24,360
+term sperm concentration معناه ببساطة عدد
+
+459
+00:32:24,360 --> 00:32:28,540
+الحيوانات المنوية في ملليلتر واحد يعني أنا عندي ملليلتر
+
+460
+00:32:28,540 --> 00:32:31,760
+واحد أكثر حيوان منوي أكثر نطفة موجودة عندي هذا
+
+461
+00:32:31,760 --> 00:32:37,600
+بسميها لإنه صار في حجم معين وهو one milliliter
+
+462
+00:32:37,600 --> 00:32:42,430
+بسميه sperm concentration الـ sperm الـ total count
+
+463
+00:32:42,430 --> 00:32:46,150
+هو عبارة عن عدد الحيوانات المنوية في العينة ككل
+
+464
+00:32:46,150 --> 00:32:51,210
+كيف تحسب؟ بقول الـ total sperm count يساوي الـ sperm
+
+465
+00:32:51,210 --> 00:32:54,910
+concentration ضرب الـ total volume يعني لو أنا اللي
+
+466
+00:32:54,910 --> 00:32:59,050
+جيت ببساطة عندي خمسة مليون as sperm concentration
+
+467
+00:32:59,050 --> 00:33:02,610
+في الـ واحد مل وعندي الـ total volume خمسة إذا ال
+
+468
+00:33:02,610 --> 00:33:07,660
+total sperm count خمسة في خمسة وعشرين مليون Sperm
+
+469
+00:33:07,660 --> 00:33:12,100
+concentration can be assessed by haemocytometer هذه
+
+470
+00:33:12,100 --> 00:33:14,960
+طريقة من طرق القياس وهي التي تعتبر reference
+
+471
+00:33:14,960 --> 00:33:20,180
+method الـ macular هو عبارة عن slide خاصة بال
+
+472
+00:33:20,180 --> 00:33:24,200
+seminal fluid يستخدم في الـ fertility center وال
+
+473
+00:33:24,200 --> 00:33:28,260
+slide method وهي عبارة عن طريقة روتينية لها طريقة
+
+474
+00:33:28,260 --> 00:33:33,920
+معينة في القياس الأصح يابتستخدم macular يابتستخدم
+
+475
+00:33:33,920 --> 00:33:38,490
+haemocytometer هذا صح The concentration of the semen
+
+476
+00:33:38,490 --> 00:33:43,110
+depending on what يعني عدد الحيوانات في الـ one
+
+477
+00:33:43,110 --> 00:33:46,790
+milliliter تعتمد على شغل أول حاجة تعتمد على volume
+
+478
+00:33:46,790 --> 00:33:50,450
+of testis حجم الـ testis جدّش كل ما زاد الحجم
+
+479
+00:33:50,450 --> 00:33:55,210
+المنطقي يقول هيزيد عملية التصنيع، هيزيد المخزون،
+
+480
+00:33:55,210 --> 00:34:00,070
+هيزيد عدد الحيوانات المقذوفة اثنين الـ period of
+
+481
+00:34:00,070 --> 00:34:03,550
+sexual absence هل امتنع عن الـ intercourse أو ال
+
+482
+00:34:03,550 --> 00:34:06,630
+ejaculation ثلاث أيام ولا أسبوع؟ طبعا هذا منطق كل
+
+483
+00:34:06,630 --> 00:34:09,950
+ما زاد الامتناع زادت عملية التحصيل والتخزين
+
+484
+00:34:09,950 --> 00:34:14,890
+فبالتالي زاد عملية الـ sperm اللي مقذوف الـ size of
+
+485
+00:34:14,890 --> 00:34:19,930
+epididymal sperm منطقي كل ما زاد الـ size يعني كل ما
+
+486
+00:34:19,930 --> 00:34:23,910
+زاد المستودع كل ما زادت عملية التخزين إذن ثلاث عوامل
+
+487
+00:34:23,910 --> 00:34:29,030
+الأساسية هي التي تساهم وتعتمد عليها عدد الحيوانات
+
+488
+00:34:29,030 --> 00:34:32,770
+المنوية أو ما يُعرف باسم الـ sperm concentration
+
+489
+00:34:32,770 --> 00:34:40,660
+sperm morphology من أشهر وأهم الـ parameter احنا
+
+490
+00:34:40,660 --> 00:34:43,660
+عارفين دائما إن الـ Sperm بتكون من head و neck و
+
+491
+00:34:43,660 --> 00:34:47,460
+mid piece و tail الـ head فيه الـ acrosome وفيه ال
+
+492
+00:34:47,460 --> 00:34:53,720
+nuclear acid الـ mid piece فيها ميتوكوندريا وال
+
+493
+00:34:53,720 --> 00:34:57,420
+flagella أو الـ tail مسئولة عن الحركة طبعا هذه
+
+494
+00:34:57,420 --> 00:35:00,220
+الصورة هي عبارة عن الـ normal shape أو الـ normal
+
+495
+00:35:00,220 --> 00:35:04,560
+form لـ Sperm في بعض الأحيان في عندي abnormal form
+
+496
+00:35:04,560 --> 00:35:10,940
+زي زيادة في الـ head size نقصان في الـ head size
+
+497
+00:35:10,940 --> 00:35:20,520
+نقصان في الـ head size نقصان في الـ head size نقصان
+
+498
+00:35:20,520 --> 00:35:22,080
+في الـ head size نقصان في الـ head size نقصان في ال
+
+499
+00:35:22,080 --> 00:35:22,320
+head size نقصان في الـ head size نقصان في ال
+
+500
+00:35:22,320 --> 00:35:22,420
+head size نقصان في الـ head size نقصان في ال head
+
+501
+00:35:22,420 --> 00:35:23,260
+size نقصان في الـ head size نقصان في ال head size نقصان
+
+502
+00:35:23,260 --> 00:35:25,060
+في الـ head size نقصان في الـ head size نقصان في ال
+
+503
+00:35:25,060 --> 00:35:26,240
+head size نقصان في الـ head size نقصان في ال
+
+504
+00:35:26,240 --> 00:35:28,540
+head size نقصان في الـ head size نقصان في ال head size
+
+505
+00:35:28,540 --> 00:35:29,880
+نقصان في الـ head size نقصان في الـ head size نقصان
+
+506
+00:35:29,880 --> 00:35:31,560
+head size نقصان في الـ head size abnormal
+
+507
+00:35:31,560 --> 00:35:35,420
+morphology may have an impact on هذه الـ abnormal
+
+508
+00:35:35,420 --> 00:35:37,760
+morphology لما أشوف abnormality عالية في ال
+
+509
+00:35:37,760 --> 00:35:41,180
+morphology للـ sperm تعطيني indication على شو؟
+
+510
+00:35:41,180 --> 00:35:44,740
+تعطيلي إن في عندي chromatin condensation بشكل غير
+
+511
+00:35:44,740 --> 00:35:50,180
+طبيعي في عندي acrosome أو عفوا بتأثر على شو؟ بتعمل
+
+512
+00:35:50,180 --> 00:35:53,480
+impact على شو؟ لما يكون عندي abnormality في ال
+
+513
+00:35:53,480 --> 00:35:54,020
+morphology
+
+514
+00:36:10,230 --> 00:36:16,610
+الحركة نشاط الـ acrosome الـ apoptosis كلهم يتأثروا
+
+515
+00:36:16,610 --> 00:36:19,590
+بالمورفولوجي يعني بمعنى آخر إن المورفولوجي السيء
+
+516
+00:36:19,590 --> 00:36:23,950
+يتأثر عليه بشكل سيء Specific morphological defects
+
+517
+00:36:23,950 --> 00:36:29,170
+such as multiple tail abnormalities or headless
+
+518
+00:36:29,170 --> 00:36:33,870
+spermatozoa may be associated with genetic
+
+519
+00:36:33,870 --> 00:36:37,650
+abnormality يعني في عندي بعض الـ abnormal form
+
+520
+00:36:37,650 --> 00:36:41,670
+اللي علاقة بالـ genetic زي فقدان الـ head على سبيل
+
+521
+00:36:41,670 --> 00:36:46,070
+المثال أو وجود أكثر من tail وجود أكثر من tail زي
+
+522
+00:36:46,070 --> 00:36:50,210
+ما أحنا شايفين في رقم ثلاثة من جهة اليمين قد يكون
+
+523
+00:36:50,210 --> 00:36:55,370
+genetical abnormality صورة بتوضح الـ abnormal بالـ
+
+524
+00:36:55,370 --> 00:37:01,870
+head double head يعني
+
+525
+00:37:01,870 --> 00:37:04,630
+حاجة مثل الـ cytoplasmic droplet بين head بين head
+
+526
+00:37:04,630 --> 00:37:08,850
+في هنا أشكال في الـ mid piece وهنا أشكال في ال
+
+527
+00:37:08,850 --> 00:37:14,390
+tail طبعا أنا ما أميل أن أحفظ الأشكال ولكن أميل أن
+
+528
+00:37:14,390 --> 00:37:19,090
+يكون في عندي صورة كاملة لكل الـ abnormal form or
+
+529
+00:37:19,090 --> 00:37:22,830
+morphology موجودة أمام الـ technician علشان يقدر
+
+530
+00:37:23,160 --> 00:37:30,000
+يُصنف شكل آخر بوضّح لي الـ abnormal form الممكن أنا
+
+531
+00:37:30,000 --> 00:37:33,140
+كـ recognition ألاقيها تحت الـ microscope أشكال اللي
+
+532
+00:37:33,140 --> 00:37:36,060
+علاقة بالـ head defect أشكال اللي علاقة بالـ mid
+
+533
+00:37:36,060 --> 00:37:40,760
+piece or neck defect أشكال اللي علاقة بالـ tail
+
+534
+00:37:40,760 --> 00:37:45,520
+defect يعني على سبيل المثال واللي أنا شفته شوفت الـ
+
+535
+00:37:45,520 --> 00:37:51,320
+megalo الـ large head شوفت الـ pin head شوفت الـ neck
+
+536
+00:37:51,320 --> 00:37:54,740
+بتكون شبه مكسورة زي الرقم اثنين هذه شوفت الـ
+
+537
+00:37:54,740 --> 00:38:01,200
+droplet cytoplasm حوالي الـ mid piece شوفت الـ thin
+
+538
+00:38:01,200 --> 00:38:07,920
+mid piece شوفت الـ coiled tail شوفت الـ bent tail أيضا
+
+539
+00:38:07,920 --> 00:38:11,580
+شوفت الـ terminal coiled tail بهذا الشكل يعني في
+
+540
+00:38:11,580 --> 00:38:14,960
+أشكال مختلفة من الـ abnormal morphology اللي ممكن
+
+541
+00:38:14,960 --> 00:38:20,650
+أنت تشوفها تحت الـ microscope مصطلح له علاقة بال
+
+542
+00:38:20,650 --> 00:38:25,670
+sperm viability وبعض الأحيان بيطلب عليه sperm
+
+543
+00:38:25,670 --> 00:38:30,130
+viability يعني بمعنى آخر حيوية الـ sperm هل ال
+
+544
+00:38:30,130 --> 00:38:34,630
+sperm حي أم ميت الـ percentage of live ended sperm
+
+545
+00:38:34,630 --> 00:38:38,470
+in the sample and it's indicative of abnormalities
+
+546
+00:38:38,470 --> 00:38:42,850
+in any of the genital organs لما أقوم أن أعمل ال
+
+547
+00:38:42,850 --> 00:38:46,550
+viability test أو الـ viability test هد بتعطيني
+
+548
+00:38:46,550 --> 00:38:49,430
+indication جدّش في عندك sperm حيّ جدّش في عندي ال
+
+549
+00:38:49,430 --> 00:38:52,970
+sperm ميت وبتعطيني indication على وجود
+
+550
+00:38:52,970 --> 00:38:56,610
+abnormality في الـ genital organ أو لا طب كيف أنا
+
+551
+00:38:56,610 --> 00:39:01,610
+ممكن أحللها؟ الـ analysis of sperm vitality is
+
+552
+00:39:01,610 --> 00:39:04,470
+based on the integrity of the sperm cell membrane
+
+553
+00:39:04,470 --> 00:39:07,730
+هذا الـ principle يعني الـ vitality test على شو
+
+554
+00:39:07,730 --> 00:39:11,630
+بتعتمد؟ تعتمد على الـ integrity تبع الـ sperm cell
+
+555
+00:39:11,630 --> 00:39:15,170
+membrane هل في عندي integrity بشكل معقول صحيح؟ هل
+
+556
+00:39:15,170 --> 00:39:20,300
+في عملو controlling لـ cell membrane على ما يدخل و
+
+557
+00:39:20,300 --> 00:39:24,760
+ما يخرج من خلية الحيوان المنوي بالشكل المطلوب ولا
+
+558
+00:39:24,760 --> 00:39:27,940
+لأ ممكن أنا أعملها evaluation لـ viability
+
+559
+00:39:27,940 --> 00:39:32,720
+باستخدام Eosin-Nigrosin stain أو باستخدام الـ hypo
+
+560
+00:39:32,720 --> 00:39:40,550
+osmotic swelling test ثلاث فحوصين مهمين جدا viability
+
+561
+00:39:40,550 --> 00:39:44,590
+is affected by a number of variables such as
+
+562
+00:39:44,590 --> 00:39:47,390
+abnormal spermatogenesis and vascular and 
+
+563
+00:39:47,390 --> 00:39:51,710
+prostatic fluid تلت عوامل بأثروا على حيوية ال
+
+564
+00:39:51,710 --> 00:39:55,390
+sperm أول حاجة ال abnormality في spermatogenesis
+
+565
+00:39:55,390 --> 00:39:58,750
+الشغل التاني ع ال abnormal في ال vascular ال
+
+566
+00:39:58,750 --> 00:40:02,310
+vascular أو ال prostatic fluid ال principle ببساطة
+
+567
+00:40:02,310 --> 00:40:06,750
+جدا أن أنا بصبغ ال sperm بصبغة ال sperm إذا كان
+
+568
+00:40:06,750 --> 00:40:10,290
+الـ Integrity تبع الـ cell membrane بتكون
+
+569
+00:40:10,290 --> 00:40:15,310
+defect فبتسنح بدخول الصبغة إذا اللي كان ال sperm
+
+570
+00:40:15,310 --> 00:40:18,910
+live ال Integrity بتكون سليمة فتمنع دخول الصبغة
+
+571
+00:40:18,910 --> 00:40:23,930
+فبالتالي بشوف أنا ال sperm in live cell membrane
+
+572
+00:40:23,930 --> 00:40:27,790
+remain intact and therefore exclude the dye from
+
+573
+00:40:27,790 --> 00:40:32,990
+penetrating بمعنى آخر إن إذا كان الحيوان المنوي حي
+
+574
+00:40:32,990 --> 00:40:39,850
+يبقى بلونه الطبيعي pale colorفاتح أما إذا كان الـ
+
+575
+00:40:39,850 --> 00:40:44,110
+sperm dead بياخد صبغة النجروسين أعفوا لل eosin أو
+
+576
+00:40:44,110 --> 00:40:47,570
+النجروسين و في الغالب صبغة ال eosin بتكون pink
+
+577
+00:40:47,570 --> 00:40:50,070
+color فبياخد اللون ال pink و هنشوفها كمان شوية
+
+578
+00:40:50,070 --> 00:40:56,090
+بصورة متى تستخدم و يجرى فحص ال viability عشان كده
+
+579
+00:40:56,090 --> 00:41:01,110
+بقولك ليس جميع المراكز تقوم بهذه الفرصات كلها تهتم 
+
+580
+00:41:01,110 --> 00:41:04,110
+بال concentration و ال motility و ال volume بينما
+
+581
+00:41:04,110 --> 00:41:09,260
+ال viability test يتم إجراءها إذا كان عدد الـ sperm
+
+582
+00:41:09,260 --> 00:41:13,320
+الـ motility أو ك percentage أقل من 10% يعني لما
+
+583
+00:41:13,320 --> 00:41:17,200
+أنا بطلع أتقرر و ألاجي عندي ال motility total
+
+584
+00:41:17,200 --> 00:41:21,400
+motile أقل من 10% المفروض أعمل viability test لأنه
+
+585
+00:41:21,400 --> 00:41:25,500
+قد يكون ال sperm صحيح immotile ولكنه live فبالتالي
+
+586
+00:41:25,500 --> 00:41:30,500
+يمكن استخدامه في الحقن المجهري ما بروحش آخد
+
+587
+00:41:30,500 --> 00:41:35,740
+testicular biopsy خزعة من ال testes طبعاً هذه
+
+588
+00:41:35,740 --> 00:41:40,040
+الصورة بتوضح الكلام اللي أنا قلته Hi في عندي صبغت
+
+589
+00:41:40,040 --> 00:41:44,080
+بال eosin الدد sperm أخد اللون ال pink في منطقة
+
+590
+00:41:44,080 --> 00:41:46,840
+ال head لأن ال integrity تبعت ال cell membrane
+
+591
+00:41:46,840 --> 00:41:51,760
+defect فسمحت بدخول الصبغة أما ال pale color أو ال
+
+592
+00:41:51,760 --> 00:41:55,880
+white color هو عبارة عن ال life sperm فبالتالي ما
+
+593
+00:41:55,880 --> 00:41:58,280
+أخد الصبغة لأن ال integrity تبعت ال cell membrane
+
+594
+00:41:58,280 --> 00:42:02,460
+كما هي فمنعت دخول الصبغة أو إن دخلت الصبغة عملت ال
+
+595
+00:42:02,460 --> 00:42:07,430
+exclusion طبعا هذه معظم النقاط اللي أنا بتتكلم عنها
+
+596
+00:42:07,430 --> 00:42:11,450
+في محاضرة اليوم، نرجو أن نكمل في المحاضرة القادمة
+
+597
+00:42:11,450 --> 00:42:13,950
+إن شاء الله، دوم توم في حفظ الله 
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/vcJ75dxZ2fw.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/vcJ75dxZ2fw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..e382376a8c24cec283ea63f402778f6f5cfde6e8
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/vcJ75dxZ2fw.srt
@@ -0,0 +1,1668 @@
+1
+00:00:01,530 --> 00:00:05,490
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,490 --> 00:00:10,230
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا 
+
+3
+00:00:10,230 --> 00:00:14,150
+الأفضل نرجو من الله العلي الكريم أن تكونوا جميعا 
+
+4
+00:00:14,150 --> 00:00:19,350
+بخير وبصحة جيدة استكمالا لما بدأنا فيه في المحاضرة
+
+5
+00:00:19,350 --> 00:00:24,030
+السابقة عن الأحداث التي تحدث أثناء عملية ال
+
+6
+00:00:24,030 --> 00:00:29,050
+fertilization توقفنا عند مصطلح مهم وهو عبارة عن
+
+7
+00:00:29,050 --> 00:00:37,290
+عدم تلقيح البويضة بأكثر من نطفة بمعنى آخر مصطلح له
+
+8
+00:00:37,290 --> 00:00:41,330
+أهمية كبيرة جدا مقصود فيه penetration of
+
+9
+00:00:41,330 --> 00:00:46,670
+polyspermia أو polyspermy كيف بيصير عملية ال
+
+10
+00:00:46,670 --> 00:00:51,370
+penetration؟ حكينا عنها بالتفصيل وشوفنا الفيديو
+
+11
+00:00:51,370 --> 00:00:54,330
+اللي بتكلم عن عملية الـ penetration  والفيديو تطرق
+
+12
+00:00:54,330 --> 00:00:59,730
+إلى عملية منع تلقيح البويضة بحيوان منوي آخر إن تم
+
+13
+00:00:59,730 --> 00:01:04,570
+تلقيحها في مصطلح مهم جدا هنتكلم عنه وهو
+
+14
+00:01:04,570 --> 00:01:08,730
+عبارة عن prevention of polyspermia ومصطلح آخر
+
+15
+00:01:08,730 --> 00:01:14,070
+اسمه ectopic pregnancy كحالة مرضية تتعرض له السيدة
+
+16
+00:01:14,070 --> 00:01:20,870
+طبعا بمجرد حدوث fusion للـ sperm ودخوله واختراقه 
+
+17
+00:01:20,870 --> 00:01:26,790
+الـ zona pellucida برقم ZP3تدخل المادة الوراثية
+
+18
+00:01:26,790 --> 00:01:30,630
+الخاصة بالـ sperm وتندمج مع المادة الوراثية الخاصة
+
+19
+00:01:30,630 --> 00:01:35,590
+بالـ oocyte لتكوين الـ zygote ولكن قبل عملية
+
+20
+00:01:35,590 --> 00:01:39,050
+الاندماج اللي يجب أن يحدث هناك بعض التغييرات على 
+
+21
+00:01:39,050 --> 00:01:43,570
+السطح الخارجي للبويضة يمنع اختراقها بـ other sperm
+
+22
+00:01:43,570 --> 00:01:49,330
+تحت مسمى «prevention of polyspermia» كيف عملية الـ
+
+23
+00:01:49,330 --> 00:01:50,550
+«prevention» بتصير؟
+
+24
+00:01:53,800 --> 00:02:00,280
+واحد Fast وواحد Slow الـ Fast Block to Polyspermia
+
+25
+00:02:00,280 --> 00:02:02,260
+هي عبارة عن عملية
+
+26
+00:02:02,260 --> 00:02:16,240
+سسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسسس
+
+27
+00:02:23,170 --> 00:02:27,070
+بمجرد دخول الـ Sperm تتغير الشحنات في أقل من ثواني
+
+28
+00:02:27,070 --> 00:02:31,590
+هذا ما نسميه الـ Electrical Depolarization فعلى
+
+29
+00:02:31,590 --> 00:02:36,030
+سبيل المثال بيصير restarting و change للـ charge
+
+30
+00:02:36,030 --> 00:02:41,250
+الموجودة على سطح الخارج للـ Oocyte فبتتحول من minus
+
+31
+00:02:41,250 --> 00:02:48,290
+17 لـ plus 10 MV خلال two second to three second
+
+32
+00:02:48,290 --> 00:02:53,000
+بعد الـ effusion اللي بيصير لـ single sperm هذا
+
+33
+00:02:53,000 --> 00:02:55,800
+التغير في الشحنة وهذا التغير في الـ polarization
+
+34
+00:02:55,800 --> 00:03:00,060
+للـ plasma membrane بعمل prevent for other sperm
+
+35
+00:03:00,060 --> 00:03:05,400
+to enter this Oocyte لأنه غير الشحنات فأصبح ال
+
+36
+00:03:05,400 --> 00:03:09,740
+sperm مش قادر يتعرف عليها حتى مش قادر يقترب أو
+
+37
+00:03:09,740 --> 00:03:15,620
+يتعرف على الزونا باليوسيدا ZP3 الـ second phase or
+
+38
+00:03:15,620 --> 00:03:20,040
+mechanism اللي بنسميها بـ  Cortical Reaction
+
+39
+00:03:20,040 --> 00:03:23,460
+mechanismوهذه الـ Slow Mechanism بتاخد فترة زمانية
+
+40
+00:03:23,460 --> 00:03:28,100
+طويلة جدا بتشارك فيها الـ Cortical Granules which
+
+41
+00:03:28,100 --> 00:03:31,400
+are small membrane-formed vesicles that are owned
+
+42
+00:03:31,400 --> 00:03:35,660
+off from Golgi apparatus during oogenesis بتشارك
+
+43
+00:03:35,660 --> 00:03:39,520
+فيها بشكل أساسي طبعا هذه الـ Cortical Granules
+
+44
+00:03:39,520 --> 00:03:42,520
+تحتوى على Protolytic enzyme and polysaccharide
+
+45
+00:03:42,520 --> 00:03:46,220
+بتسمى polysaccharide يعني بشكل أساسي في عندي
+
+46
+00:03:46,220 --> 00:03:49,480
+Protolytic enzyme في عندي polysaccharide وفي عندي
+
+47
+00:03:49,480 --> 00:03:55,300
+cortical granuleهي تتوزع بشكل كبير جدا على محيط
+
+48
+00:03:55,300 --> 00:04:01,280
+الـ plasma membrane الخاص بالـ oocyte بمجرد دخول
+
+49
+00:04:01,280 --> 00:04:06,100
+الـ sperm يبدأ إفراز كمية كبيرة جدا من الكالسيوم
+
+50
+00:04:06,100 --> 00:04:10,620
+على شكل نبضات على شكل waves through the
+
+51
+00:04:10,620 --> 00:04:14,520
+cytoplasm of the oocyte the first set of waves
+
+52
+00:04:14,520 --> 00:04:18,580
+separating from the site of sperm egg fusion يعني
+
+53
+00:04:18,580 --> 00:04:25,040
+خلال دخول الـ sperm للـ oocyte يبدأ خروج نبضات و ..
+
+54
+00:04:25,040 --> 00:04:30,100
+و مجموعات من .. و كميات من الكالسيوم على شكل نبضات
+
+55
+00:04:30,100 --> 00:04:35,740
+متتالية أول نبضة وأول موجة يتم خروجها من منطقة
+
+56
+00:04:35,740 --> 00:04:39,800
+دخول الـ sperm الـ sperm دخل على الـ oocyte من
+
+57
+00:04:39,800 --> 00:04:43,980
+منطقة اسمها X مباشرة من هذه المنطقة يفرز كميات
+
+58
+00:04:43,980 --> 00:04:51,940
+هائلة من الـ calcium تحت مصطلح efflux تحت مصطلح من
+
+59
+00:04:51,940 --> 00:04:59,080
+الخارج يعني
+
+60
+00:04:59,080 --> 00:05:02,240
+هذه العملية النبضة الأولى أو الدفعة الأولى أو
+
+61
+00:05:02,240 --> 00:05:07,080
+الدفقة الأولى من الكالسيوم اللي بيخرج من منطقة
+
+62
+00:05:07,080 --> 00:05:11,960
+دخول الـ sperm أول دفقة أو أول دفعة أو أول موجة من
+
+63
+00:05:11,960 --> 00:05:15,600
+الـ calcium wave اللي بتخرج تعمل switch on عشان
+
+64
+00:05:15,600 --> 00:05:19,650
+تكمل الـ oocyte الانقسام الميوزي الثاني الميوزي
+
+65
+00:05:19,650 --> 00:05:23,430
+الثاني الذي توقفت فيه في الـ Metaphase II من
+
+66
+00:05:23,430 --> 00:05:29,170
+انقسام الميوزي الثاني يلي التدافعات وموجات متتالية
+
+67
+00:05:29,170 --> 00:05:34,330
+من إفرازات من الكالسيوم تعمل عملية نسميها initiated
+
+68
+00:05:34,330 --> 00:05:40,510
+of maternal RNA in the egg and act on the cortical
+
+69
+00:05:40,510 --> 00:05:44,230
+granule at the base by them يعني تعمل على تنشيط
+
+70
+00:05:44,230 --> 00:05:47,600
+الـ cortical granule علشان تبدأ في الشغل المطلوب
+
+71
+00:05:47,600 --> 00:05:53,600
+منها عرض الـ cortical granule للكالسيوم ودفعات
+
+72
+00:05:53,600 --> 00:05:57,940
+الكالسيوم وموجات الكالسيوم المفرزة  بتسبب
+
+73
+00:05:57,940 --> 00:06:01,420
+fuse with the plasma membrane and release their
+
+74
+00:06:01,420 --> 00:06:05,800
+content on the perivitelline space يعني مجرد ما تتنشط
+
+75
+00:06:05,800 --> 00:06:09,320
+الـ cortical granule وتتعرض لدفعات ودفقات وموجات من
+
+76
+00:06:09,320 --> 00:06:14,340
+الكالسيوم الذي يفرز تعمل Cortical Granule اندفاع
+
+77
+00:06:14,340 --> 00:06:17,900
+نحو الـ Plasma Membrane الخاص للـ Oocyte و بتفرغ
+
+78
+00:06:17,900 --> 00:06:21,900
+محتوها داخل هذه المنطقة ماهي المنطقة؟ هي الـ
+
+79
+00:06:21,900 --> 00:06:28,200
+Perivitelline Space تفرغ Cortical Granule محتواتها في
+
+80
+00:06:28,200 --> 00:06:31,840
+هذه المنطقة الـ Polysaccharide released into
+
+81
+00:06:44,080 --> 00:06:49,540
+أيضا تتعرض الـ Cortical Granule للكالسيوم بدأت
+
+82
+00:06:49,540 --> 00:06:52,340
+تهاجر في اتجاه الـ Plasma Membrane للـ Oocyte
+
+83
+00:06:52,340 --> 00:06:55,560
+ووصلت للـ Plasma Membrane للـ Oocyte صارت Fusion
+
+84
+00:06:55,560 --> 00:07:00,590
+اندمجت فيه أفرغت محتوياتها من الـ lytic enzyme و
+
+85
+00:07:00,590 --> 00:07:03,350
+الـ proteolytic enzyme والـ polysaccharide في الـ
+
+86
+00:07:03,350 --> 00:07:08,170
+space اللي سميته perivitelline space فأصبح ال
+
+87
+00:07:08,170 --> 00:07:11,210
+polysaccharide موجود في هذه المنطقة خلى هذه
+
+88
+00:07:11,210 --> 00:07:15,190
+المنطقة rigid .. rigid .. rigid .. rigid خلىها
+
+89
+00:07:15,190 --> 00:07:21,850
+rigid يعني very .. not flexible صلبة غير قادر ال
+
+90
+00:07:21,850 --> 00:07:26,210
+sperm من اختراقها الشيء الثاني من نشطة الـ cortical
+
+91
+00:07:26,210 --> 00:07:33,150
+granule تدفع إلى بروز من zona pellucida وهيدروليسيز
+
+92
+00:07:33,150 --> 00:07:39,190
+الـ sperm receptor جزيء zona pellucida يعني
+
+93
+00:07:39,190 --> 00:07:43,130
+الإنزيمات اللي كانت في الـ cortical granule أفرزت
+
+94
+00:07:43,130 --> 00:07:45,710
+والبوليساكاريد الموجود في الـ cortical granule
+
+95
+00:07:45,710 --> 00:07:51,610
+أفرز البوليساكاريد خلى الـ perivitelline space أكثر
+
+96
+00:07:51,610 --> 00:07:57,180
+صلابة فبالتالي صعب أن يخترقوا الـ sperm أيضًا ال ..
+
+97
+00:07:57,180 --> 00:08:01,200
+ال .. ال .. البروتاليتك إنزيم أو البروتيز إنزيم
+
+98
+00:08:01,200 --> 00:08:03,620
+الموجود في الـ cortical granule اللي موجود في هذا
+
+99
+00:08:03,620 --> 00:08:07,020
+المنطقة عملت على تدمير الريسبتور الموجود في
+
+100
+00:08:07,020 --> 00:08:09,620
+الـ zona pellucida الخاص بالـ sperm فأصبح الـ sperm
+
+101
+00:08:09,620 --> 00:08:13,800
+غير قادر على التعرف على الريسبتور أيضًا تغيير
+
+102
+00:08:13,800 --> 00:08:17,720
+الـ zona pellucida إلى 2 جزيء هذه الاتفاقية اسمها
+
+103
+00:08:17,720 --> 00:08:20,300
+الاتفاقية الـ zona pellucida أساسًا elimination
+
+104
+00:08:24,490 --> 00:08:28,610
+or adhere to and penetrate the zona pellucida يعني
+
+105
+00:08:28,610 --> 00:08:33,670
+هذه الأحداث اللي صارت تشمل الـ space وتدمير الـ zona
+
+106
+00:08:33,670 --> 00:08:38,090
+pellucida وتقطيع الـ zona pellucida receptor وتقطيع
+
+107
+00:08:38,090 --> 00:08:43,330
+الـ zona pellucida إلى 2 جزيء أدى إلى فقدان قدرته
+
+108
+00:08:43,330 --> 00:08:47,050
+قدرته على التعرف على الـ receptor الموجودة في ال
+
+109
+00:08:47,050 --> 00:08:49,870
+plasma membrane أو الموجودة في الـ zona pellucida
+
+110
+00:08:49,870 --> 00:08:52,570
+رقم 3 وبالتالي فقد قدرته على
+
+111
+00:08:57,470 --> 00:09:04,530
+الـ slowly phase of polyspermy prevention خليني 
+
+112
+00:09:04,530 --> 00:09:09,330
+نشوف الفيديو اللي بتكلم عن هذا الموضوع بشكل أساسي
+
+113
+00:09:09,330 --> 00:09:16,070
+بس هذا الفيديو سريع شوفوا 
+
+114
+00:09:16,070 --> 00:09:20,830
+كيف صار انتفاخ للويضة بمجرد دخول الـ sperm الخاص
+
+115
+00:09:20,830 --> 00:09:28,060
+فيها نعيده مرة ثانية مع بعض التأكيد خليني أتفرج
+
+116
+00:09:28,060 --> 00:09:31,520
+عليها دي دخل الـ sperm عامل penetration صار انتفاخ
+
+117
+00:09:31,520 --> 00:09:34,880
+البويضة بفعل إفراز الـ polysaccharide وإفراز الـ
+
+118
+00:09:34,880 --> 00:09:39,840
+lytic enzyme هذا بالنسبة لعملية الـ blocking كيف
+
+119
+00:09:39,840 --> 00:09:46,040
+تمنع البويضة نفسها من التلقيح بـ sperm آخر بالتالي،
+
+120
+00:09:46,040 --> 00:09:49,460
+بعد penetration من الـ Oocyte إلى الـ spermatozoon من
+
+121
+00:09:49,460 --> 00:09:52,420
+خلال الـ spermatozoon بالتأكيد، نكولة الـ Oocyte
+
+122
+00:09:52,420 --> 00:09:58,000
+يجب أن تندمج مع نكولة الـ sperm ولكن قبل أن يحدث
+
+123
+00:09:58,000 --> 00:10:02,200
+الاندماج، يجب أن يكتمل انقسام الميوزي الثاني لأن
+
+124
+00:10:02,200 --> 00:10:08,390
+البويضة توقفت في الـ Metaphase II اكتمال انقسام
+
+125
+00:10:08,390 --> 00:10:11,530
+الميوزي الثاني، ظهور الـ second polar body في
+
+126
+00:10:11,530 --> 00:10:15,570
+منطقة الـ perivitelline space.Cytoplasmic factors
+
+127
+00:10:15,570 --> 00:10:19,670
+control the growth of female and male pronuclear
+
+128
+00:10:19,670 --> 00:10:25,370
+.البرونيوكليار تظهر بعد الإخصاب بـ 6 إلى 8 ساعات كحد
+
+129
+00:10:25,370 --> 00:10:29,390
+أدنى and they continue for approximately 10 to
+
+130
+00:10:29,390 --> 00:10:34,230
+12 hours.يعني هذه البرونيوكليار تظهر بعد عملية ال
+
+131
+00:10:34,230 --> 00:10:40,540
+penetration بـ 8 ساعات كحد أدنى وتبقى كما هي لمدة 12
+
+132
+00:10:40,540 --> 00:10:44,480
+ساعة كحد أقصى when the male and female pronuclear
+
+133
+00:10:44,480 --> 00:10:47,920
+come into contact their membrane breakdown and the
+
+134
+00:10:47,920 --> 00:10:52,440
+chromosomes will be fused علشان يكونوا نواة جديدة
+
+135
+00:10:52,440 --> 00:10:58,060
+بنسميها الزيجوت يعني بمعنى آخر الزيجوت هي عبارة عن
+
+136
+00:10:58,060 --> 00:11:02,380
+محصلة اندماج النواة الذكرية اللي كانت عادت من
+
+137
+00:11:02,380 --> 00:11:05,860
+الإسبرم مع النواة الأنثوية اللي كانت بالبويضة
+
+138
+00:11:05,860 --> 00:11:10,260
+عشان تكونوا نواة واحدة بيسميها Zygote وهي عبارة عن
+
+139
+00:11:10,260 --> 00:11:15,960
+المادة الأساسية لتكوين الجنين هذا بالنسبة للـ
+
+140
+00:11:15,960 --> 00:11:18,460
+penetration والـ fertilization ومكان حدوث ال
+
+141
+00:11:18,460 --> 00:11:20,840
+fertilization والمعوقات اللي بتواجه ال
+
+142
+00:11:20,840 --> 00:11:24,520
+fertilization والقُليّة التي تعتمد عليها البويضة 
+
+143
+00:11:24,520 --> 00:11:30,060
+لمنع القيحة بأكثر من نطفة في مصطلح كتير بنسمعه اسم 
+
+144
+00:11:30,060 --> 00:11:30,820
+Ectopic Pregnancy
+
+145
+00:11:34,240 --> 00:11:37,240
+الأكتوبيك برجننسي ببساطة جدا هي حالة مرضية وقد
+
+146
+00:11:37,240 --> 00:11:40,980
+تؤدي إلى الوفاة في بعض الأحيان. أكتوبيك برجننسي
+
+147
+00:11:40,980 --> 00:11:45,980
+هي عبارة عن الحمل خارج الرحم. المفروض والمنطقي أن
+
+148
+00:11:45,980 --> 00:11:48,900
+الجنين يصير له Implementation في بطانة الرحم عشان
+
+149
+00:11:48,900 --> 00:11:52,780
+يتكون له بلاسنتا ويتكون له جنين. في الأكتوبيك 
+
+150
+00:11:52,780 --> 00:11:56,360
+البرجننسي بيصير خارج الرحم. قد يصير في بداية الرحم 
+
+151
+00:11:56,900 --> 00:12:00,120
+في نهاية فالوبيان تيوب، في بداية فالوبيان تيوب، في
+
+152
+00:12:00,120 --> 00:12:02,980
+منطقة أخرى غير المنطقة المخصصة لها، عشان كده 
+
+153
+00:12:02,980 --> 00:12:08,120
+بيسموها حمل خارج الرحم، وهي حالة خطيرة
+
+154
+00:12:08,120 --> 00:12:11,540
+جدا. الـ Ectopic Pregnancy most often occurred in
+
+155
+00:12:11,540 --> 00:12:15,040
+Fallopian tube for example which carried egg from
+
+156
+00:12:15,040 --> 00:12:18,920
+the ovary to the uterus. This type of Ectopic Pregnancy
+
+157
+00:12:18,920 --> 00:12:21,880
+called a Tubular Pregnancy. يعني إذا صار الـ
+
+158
+00:12:21,880 --> 00:12:25,220
+Ectopic Pregnancy في منطقة الفالوبيان تيوب بسميها
+
+159
+00:12:25,220 --> 00:12:28,700
+Tubular Pregnancy. Ectopic Tubular Pregnancy أو
+
+160
+00:12:28,700 --> 00:12:34,680
+Tubular Pregnancy as we wish. Sometime Ectopic 
+
+161
+00:12:34,680 --> 00:12:37,940
+Pregnancy occur in other side for example Ovary
+
+162
+00:12:37,940 --> 00:12:40,360
+ممكن يصير في الـ Ovary؟ آه ممكن يصير في الـ Ovary
+
+163
+00:12:40,360 --> 00:12:44,840
+Abdominal Cavity or the lower part of Uterus في 
+
+164
+00:12:44,840 --> 00:12:49,240
+السرڤيكال. يعني في أكتر من منطقة ممكن يصير فيها الـ
+
+165
+00:12:49,240 --> 00:12:52,520
+Ectopic Pregnancy ولكن الأكثر انتشارا هي في
+
+166
+00:12:52,520 --> 00:12:56,220
+الفلوبيان تيوب اللي سميتها Tubular Pregnancy. الـ
+
+167
+00:12:56,220 --> 00:12:59,880
+Ectopic Pregnancy cannot proceed... cannot...
+
+168
+00:12:59,880 --> 00:13:03,700
+cannot be still for a long time لأنه شيء not
+
+169
+00:13:03,700 --> 00:13:07,620
+normal. فالمفروض يصير له Elimination أو يحدث له 
+
+170
+00:13:07,620 --> 00:13:10,740
+Elimination. The fertilized egg cannot be survived
+
+171
+00:13:10,740 --> 00:13:16,320
+and growing tissue may cause life limiting bleeding.
+
+172
+00:13:16,320 --> 00:13:21,320
+and if left untreated. يعني بمعنى آخر البويضة
+
+173
+00:13:21,320 --> 00:13:26,660
+المفروض بعد 24 ساعة يصير لها Elimination يا إما 
+
+174
+00:13:26,660 --> 00:13:29,200
+بيصير لها Absorption يا إما بيصير لها خروج مع الدورة
+
+175
+00:13:29,200 --> 00:13:33,380
+هذا منطق لأن الـ Sperm بايش 73 ساعة زي ما حكينا
+
+176
+00:13:33,380 --> 00:13:37,940
+فبالتالي الـ Ectopic Pregnancy إذا لم يعالج حدث
+
+177
+00:13:37,940 --> 00:13:42,000
+في منطقة معينة ولم يعالج يؤدي إلى النزيف وقد يؤدي 
+
+178
+00:13:42,000 --> 00:13:47,410
+إلى فقدان الحياة. طبعا إذا لم يعالج... إذا لم يعالج
+
+179
+00:13:47,410 --> 00:13:51,190
+هذه الشكل بنسميها على اليسار الـ Normal Pregnancy.
+
+180
+00:13:51,190 --> 00:13:55,550
+إن عند الـ Ovary بيصير عندي Ovulation بويضة وخصبة
+
+181
+00:13:55,550 --> 00:13:59,330
+بتمشي على طول الـ Fallopian Tube في بطانة الرحم
+
+182
+00:13:59,330 --> 00:14:02,750
+بيصير الـ Fertilized Egg Implanted عملية ال
+
+183
+00:14:02,750 --> 00:14:07,410
+Implantation عشان تكون للمشيمة فيما بعد. على اليسار
+
+184
+00:14:07,410 --> 00:14:10,810
+الصورة في عندي Fallopian... في عندي مناطق حدوث الـ
+
+185
+00:14:10,810 --> 00:14:16,180
+Ectopic Pregnancy. في هنا عندي أيضا صار لها
+
+186
+00:14:16,180 --> 00:14:20,820
+Ovulation. مشيت خُصبت التصقت بجدار الداخل
+
+187
+00:14:20,820 --> 00:14:24,340
+الفلوبيان تيوب وبقيت كما هي Fertilized Egg
+
+188
+00:14:24,340 --> 00:14:27,080
+implanted in the fallopian tube. نسميه Tubular
+
+189
+00:14:27,080 --> 00:14:30,420
+Pregnancy وهذا منطقة خطيرة ممكن يصير في ال
+
+190
+00:14:30,420 --> 00:14:33,980
+Isthmus نهاية الفلوبيان تيوب ممكن ممكن يصير في
+
+191
+00:14:33,980 --> 00:14:37,400
+منطقة الـ Cervix ممكن وهذا منطقة حاجة خطيرة جدا 
+
+192
+00:14:37,400 --> 00:14:43,930
+لأن المفروض الجنين بده يكبر بده يصير له تمدد، بالتالي 
+
+193
+00:14:43,930 --> 00:14:47,450
+ممكن يعمل Rupture للفلوبيان تيوب وتمزق فيها
+
+194
+00:14:47,450 --> 00:14:52,370
+فبالتالي يفقد أو تفقد السيدة القدرة على الإنجاب.
+
+195
+00:14:52,370 --> 00:14:57,550
+مرة أخرى إن لم يتم معالجته. الـ Symptoms ببساطة جدا
+
+196
+00:14:57,550 --> 00:15:01,750
+في Some Women with an ectopic pregnancy have the
+
+197
+00:15:01,750 --> 00:15:04,290
+usually early signs and symptoms of pregnancy
+
+198
+00:15:04,290 --> 00:15:08,970
+missed period, missed tendency, nausea
+
+199
+00:15:14,240 --> 00:15:17,240
+بعض السيدات اللي عندهم Ectopic Pregnancy بيظهر
+
+200
+00:15:17,240 --> 00:15:21,700
+عليهم أعراض الحمل الطبيعية جدا. فقدان الدورة، فشل
+
+201
+00:15:21,700 --> 00:15:25,760
+دورة، تظهر عندها السيدة، في عندها تجمد في منطقة الـ
+
+202
+00:15:25,760 --> 00:15:30,340
+Breast، تصلب في عندها غفيان، في عندها إرهاق
+
+203
+00:15:33,860 --> 00:15:38,380
+الـ PSG بحث الحمل هتطلع Positive. خدوا بالك فيه فرق 
+
+204
+00:15:38,380 --> 00:15:41,660
+بين الـ Ectopic Pregnancy وفيه فرق بين الحمل...
+
+205
+00:15:41,660 --> 00:15:45,460
+يعني الحمل خارج الرحم وفيه فرق بين الحمل العنقودي 
+
+206
+00:15:45,460 --> 00:15:48,860
+و الحمل الكاذب. دولة تلات مصطلحات مختلفين عن بعضهم 
+
+207
+00:15:48,860 --> 00:15:52,780
+البعض... بعضهم البعض. طب إيش أهم السمكة... الـ Sign 
+
+208
+00:15:52,780 --> 00:15:56,080
+الخاص بالـ Ectopic Pregnancy؟ أهمها أول حاجة بيصير 
+
+209
+00:15:56,080 --> 00:16:00,470
+عندي Vaginal Bleeding وبالذات في جانب اليدك بتكون
+
+210
+00:16:00,470 --> 00:16:03,770
+خفيفة جدا لأنه أصلا مافيش دورة لأنه في حمل بس 
+
+211
+00:16:03,770 --> 00:16:09,710
+الحمل مش في مكانه. بيصير في عندي Headache صداع
+
+212
+00:16:09,710 --> 00:16:14,450
+بيصير في عندي ألم واضطرابات في المعدة ومع Vomiting
+
+213
+00:16:14,450 --> 00:16:18,290
+عشان كده بنسميه Vomiting وغفيان بيصير في عندي
+
+214
+00:16:18,290 --> 00:16:23,610
+تقلصات في عضلات الـ Abdominal بيصير في عندي Pain في
+
+215
+00:16:23,610 --> 00:16:26,690
+One Side of the body وإن صار في Implantation بيصير
+
+216
+00:16:26,690 --> 00:16:31,080
+في عندي ألم. بيصير عندي Weakness بشكل عام، فيصير في 
+
+217
+00:16:31,080 --> 00:16:35,840
+عندي Pain في الـ Neck والـ Shoulder هذه كلها تعتبر 
+
+218
+00:16:35,840 --> 00:16:40,680
+Sign لـ Ectopic Pregnancy. طيب الـ Ectopic
+
+219
+00:16:40,680 --> 00:16:44,820
+Pregnancy Causes and Risk Factor لو بدأنا بالـ Most
+
+220
+00:16:44,820 --> 00:16:48,180
+Common وهو عبارة عن Tubular Pregnancy نقول The 
+
+221
+00:16:48,180 --> 00:16:50,560
+Most Common Type of Ectopic Pregnancy happened is
+
+222
+00:16:50,560 --> 00:16:53,280
+Tubular Pregnancy يعني بتحدث في الـ Follow up
+
+223
+00:16:53,280 --> 00:16:58,040
+behind a tube. سببين بشكل أساسي When Fertilized Egg
+
+224
+00:16:58,040 --> 00:17:02,720
+Get Stick on the on its way to the Uterus Often
+
+225
+00:17:02,720 --> 00:17:05,340
+because the Fallopian Tube is damaged by the
+
+226
+00:17:05,340 --> 00:17:10,680
+Deformation or Mishappen. بمعنى آخر أن ممكن الـ
+
+227
+00:17:10,680 --> 00:17:13,900
+Oocyte يصير لها Fertilization بشكل طبيعي في الـ
+
+228
+00:17:13,900 --> 00:17:17,400
+Fallopian Tube وخلال رحلتها من الـ Fallopian Tube 
+
+229
+00:17:17,400 --> 00:17:21,900
+لليوتيرس صار فيها لها انغراس في البطانة الداخلية
+
+230
+00:17:21,900 --> 00:17:25,750
+للـ Fallopian Tube. يصير لها Implantation وبالتالي
+
+231
+00:17:25,750 --> 00:17:30,410
+هتستقر في هذه المنطقة. لو كبر وصار جنين طبعا هي
+
+232
+00:17:30,410 --> 00:17:34,110
+السيدة ما عليها علم بالموضوع هذا عملت فحص الـ Pregnancy
+
+233
+00:17:34,110 --> 00:17:37,630
+وطلعت Positive ما راحت راجعة للطبيب عشان كده بنقول
+
+234
+00:17:37,630 --> 00:17:42,310
+أن أي سيدة صار عندها Intercourse بعد كده عملت فحص 
+
+235
+00:17:42,310 --> 00:17:46,010
+الحمل وصارت Positive ولجت فحص الحمل Positive لازم
+
+236
+00:17:46,010 --> 00:17:50,150
+تتابع الطبيب عشان تتأكد أن الحمل حدث بشكل صحيح وفي
+
+237
+00:17:50,150 --> 00:17:53,770
+المكان الصحيح صار الـ Implantation. هذا المنطق قدامش 
+
+238
+00:17:53,770 --> 00:17:57,170
+كده بيقولوا لازم يصير متابعة بشكل شهري للسيدة
+
+239
+00:17:57,170 --> 00:18:01,730
+الحامل. فبالتالي ما راحتش تتابع صار عندها تضخم صار 
+
+240
+00:18:01,730 --> 00:18:05,330
+عندها انفجار في الفلوبيان تيوب فبالتالي فقدت جزء
+
+241
+00:18:05,330 --> 00:18:07,650
+من الـ Reproductive System وهو عبارة عن 
+
+242
+00:18:07,650 --> 00:18:11,370
+الفلوبيان تيوب. ليه المفروض يصير في عملية الحمل الـ
+
+243
+00:18:11,370 --> 00:18:15,470
+Fertilization فبالتالي مستقبلا لن تستفيد من هذا
+
+244
+00:18:15,470 --> 00:18:19,180
+الفلوبيان تيوب. Hormonal imbalance or abnormal
+
+245
+00:18:19,180 --> 00:18:22,720
+development of the fertilized egg also maybe play
+
+246
+00:18:22,720 --> 00:18:27,360
+a role. بعض الأحيان يصير عندي Problem ومشكلة في
+
+247
+00:18:27,360 --> 00:18:30,560
+الهرمونات المفروضة بعد عملية الـ Fertilization 
+
+248
+00:18:30,560 --> 00:18:36,400
+فبالتالي تجعل البويضة تغرز وتنغمس في مكان آخر. إيش 
+
+249
+00:18:36,400 --> 00:18:39,540
+الـ Risk Factor اللي ممكن تزيد من فرصة حدوث 
+
+250
+00:18:39,540 --> 00:18:42,520
+الـ Ectopic Pregnancy؟ عندي أكتر من Risk Factor،
+
+251
+00:18:42,520 --> 00:18:45,980
+حنتكلم فيها كمان شوية، بس يشوف الفيديو هذا
+
+252
+00:18:55,800 --> 00:19:01,260
+التّرَاث الأكتوبي هو تراث يحدث خارج الرحم. عادةً
+
+253
+00:19:01,260 --> 00:19:05,420
+تحدث التّراث في أجزاء أجزاء الـ Fallopian Tube.
+
+254
+00:19:05,840 --> 00:19:09,440
+فالرّحم التّرابيّ يتّجه إلى الرحم الّذي يجب أن يتمّ
+
+255
+00:19:09,440 --> 00:19:13,820
+امتلاكه. التّرَاث الأكتوبيّ يحدث عندما يصيب البويضة على
+
+256
+00:19:13,820 --> 00:19:18,960
+طريقه ويبدأ في التّطور داخل الّرحم. هذا يُعرَف كتابة
+
+257
+00:19:18,960 --> 00:19:19,680
+تّراث رَحميّ.
+
+258
+00:19:25,610 --> 00:19:29,630
+ولكن التّجارب التجريبيّة هي بالطّبع أكثر عمومًا، مع
+
+259
+00:19:29,630 --> 00:19:33,030
+اختيارات عامّة غير عاديّة، لا يمكن للفتاة أن تنجح
+
+260
+00:19:33,030 --> 00:19:38,380
+خارج الرحم، بدون تجارب، ربط الجسد قد يتحرك التي 
+
+261
+00:19:38,380 --> 00:19:42,420
+تسبب في إدمان المصادر الموجودة حولها ومخاطر حياته
+
+262
+00:19:42,420 --> 00:19:44,200
+كبيرة، يمكن أن تكون حرارة حياته حياته حياته حياته
+
+263
+00:19:44,200 --> 00:19:48,500
+حياته حياته حياته حياته حياته حياته حياته حياته
+
+264
+00:19:48,500 --> 00:20:04,780
+حياته حياته
+
+265
+00:20:05,900 --> 00:20:08,580
+ممكن أيضًا أن يكون هناك صعوبة في الرحم إذا كانت 
+
+266
+00:20:08,580 --> 00:20:10,520
+الـ Fallopian Tube رَبشّة، يمكن أن يكون هناك 
+
+267
+00:20:10,520 --> 00:20:16,700
+عَواقِب، عَواقِب، أو فَجأة. هذه مجرد أمور مهمّة
+
+268
+00:20:16,700 --> 00:20:22,080
+ومحتاجة إلى اهتمام مباشر. يحدث الفطورية بسبب مشاكل
+
+269
+00:20:22,080 --> 00:20:25,000
+في Transportation of the fertilized egg through
+
+270
+00:20:25,000 --> 00:20:28,320
+the tube. الـ Fallopian Tubes مُلْعَقَةٌ مع أهداب مثل
+
+271
+00:20:28,320 --> 00:20:33,440
+الشعر تُدْعى Cilia. يساعدوا في تحريك البويضة. من المؤكد 
+
+272
+00:20:33,440 --> 00:20:38,460
+بأن تقليل عدد الـ Cilia قد يقلل حركة البويضة ويؤدي إلى 
+
+273
+00:20:38,460 --> 00:20:43,480
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+274
+00:20:43,480 --> 00:20:45,340
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+275
+00:20:45,340 --> 00:20:45,380
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+276
+00:20:45,380 --> 00:20:45,460
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+277
+00:20:45,460 --> 00:20:51,140
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+278
+00:20:51,140 --> 00:20:57,150
+Chlamydia أو Infection من أجزاء الرحم، أجزاء
+
+279
+00:20:57,150 --> 00:20:59,370
+الرحم تسبب في Infection من أجزاء الرحم تسبب في 
+
+280
+00:20:59,370 --> 00:21:01,870
+Infection من أجزاء الرحم تسبب في Infection من أجزاء 
+
+281
+00:21:01,870 --> 00:21:02,570
+الحرارة تسبب في إينفكشن من أعضاء الحرارة تسبب في
+
+282
+00:21:02,570 --> 00:21:04,810
+إينفكشن من أعضاء الحرارة تسبب في إينفكشن من أعضاء
+
+283
+00:21:04,810 --> 00:21:08,590
+الحرارة تسبب في إينفكشن من أعضاء الحرارة تسبب في
+
+284
+00:21:08,590 --> 00:21:12,470
+إينفكشن من أعضاء الحرارة تسبب في إينفكشن من أعضاء
+
+285
+00:21:12,470 --> 00:21:17,740
+الحرارة تسبب في إينفكشن التراث الأكتوبيكي السابق
+
+286
+00:21:17,740 --> 00:21:27,600
+مطلوبات غير طبيعية بسبب مخاطر الطفولة الناس الذين 
+
+287
+00:21:27,600 --> 00:21:33,440
+أخذوا الإستروجين الدياتلستوبسترال في مرحلة أبناء
+
+288
+00:21:33,440 --> 00:21:36,400
+أبناء أبناء أبناء أبناء أبناء أبناء أبناء أبناء
+
+289
+00:21:36,400 --> 00:21:36,440
+أبناء أبناء أبناء أبناء أبناء أبناء أبناء أبناء
+
+290
+00:21:36,440 --> 00:21:36,500
+أبناء أبناء أبناء أبناء أبناء أبناء أبناء أبناء
+
+291
+00:21:36,500 --> 00:21:39,840
+أبناء أبناء أبناء أبناء أبناء أبناء
+
+292
+00:21:39,840 --> 00:21:43,070
+أبناء إذا تم إتجار البرمجة الأكتوبيكية بسرعة، يمكن أن 
+
+293
+00:21:43,070 --> 00:21:48,350
+يتم إدخال ميثوتركسي لتدمير عضو البرمجة في حالات
+
+294
+00:21:48,350 --> 00:21:50,850
+أخرى، يمكن أن يتم إدخال عبارة عن عبارة عن عبارة عن
+
+295
+00:21:50,850 --> 00:21:51,070
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+296
+00:21:51,070 --> 00:21:52,430
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+297
+00:21:52,430 --> 00:21:53,630
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+298
+00:21:53,630 --> 00:21:55,510
+عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن
+
+299
+00:21:55,510 --> 00:22:06,730
+عبارة عن عبارة عن عبارة عن عبارة عن عبارة عن عبارة
+
+300
+00:22:07,170 --> 00:22:14,370
+HCG مرتفع يبقى عالي يتطلب تقديم أكثر شكرا للمشاهدة
+
+301
+00:22:14,370 --> 00:22:20,610
+زي ما شوفنا الـ Ectopic Pregnancy حالة مش بسيطة قد
+
+302
+00:22:20,610 --> 00:22:25,370
+تؤدي إلى ال Infertility عند السيدة إذا حدثت نمرة
+
+303
+00:22:25,370 --> 00:22:29,430
+واحدة بدون الانتباه إليها وصار ربتشر طبعا لأنها
+
+304
+00:22:29,430 --> 00:22:32,090
+هتفقد جزء من ال reproductive system هو ال
+
+305
+00:22:32,090 --> 00:22:33,250
+Fallopian tube المهم جدا
+
+306
+00:22:36,560 --> 00:22:39,400
+من خلال وجود بعض الـ imbalance في الغرمونات من
+
+307
+00:22:39,400 --> 00:22:44,720
+خلال تناول بعض المواد قد تكون سامة أخدنا فكرة عن
+
+308
+00:22:44,720 --> 00:22:49,080
+ال risk factor زي ال Smoking زي أخد الإستروجين
+
+309
+00:22:49,080 --> 00:22:55,860
+external dose يعني بمعنى آخر الإستروجين الخارجي
+
+310
+00:22:55,860 --> 00:22:59,920
+لعلاج معين هذه معظمها عبارة عن risk factor
+
+311
+00:23:02,350 --> 00:23:04,890
+بعض ال risk factors اللي هنذكرها أول حاجة
+
+312
+00:23:04,890 --> 00:23:08,650
+ال Ectopic Pregnancy السابق يعني معناه ممكن يصير في
+
+313
+00:23:08,650 --> 00:23:11,430
+عندي Ectopic Pregnancy في المستقبل ال Inflammation
+
+314
+00:23:11,430 --> 00:23:14,030
+في منطقة ال reproductive system أو ال Fallopian tube
+
+315
+00:23:14,030 --> 00:23:19,510
+ال Tibial surgery إذا صار عندي عملية جراحية في ال
+
+316
+00:23:19,510 --> 00:23:23,890
+Tibials معناه ممكن يصير Scar أو ممكن يصير Adhesion
+
+317
+00:23:23,890 --> 00:23:28,130
+أو ممكن يصير Filament for example فهذه كلها
+
+318
+00:23:28,130 --> 00:23:36,160
+مستقبلا قد تؤدي إلى بشكل أساسي في عندي أيضا ال
+
+319
+00:23:36,160 --> 00:23:40,340
+Smoking كسبب أو عامل في عندي ال Increasing في ال
+
+320
+00:23:40,340 --> 00:23:43,840
+Maternal age أكثر من 35 سنة في عندي ال Sexual
+
+321
+00:23:43,840 --> 00:23:48,780
+Transmitted disease ال STD في عندي ال Fertility
+
+322
+00:23:48,780 --> 00:23:52,140
+Drug اللي بتاخدها السيدة من أجل منع الحمل أو تأثير
+
+323
+00:23:52,140 --> 00:23:55,620
+الحمل هذا بأثر سلبا بشكل كبير جدا في عند الـ
+
+324
+00:23:55,620 --> 00:24:01,220
+Endometriosis وهي البقانة المهاجرة التي قد تسكن في
+
+325
+00:24:01,220 --> 00:24:04,380
+منطقة الـ Fallopian tube وتؤدي إلى تكوين Activity
+
+326
+00:24:04,380 --> 00:24:08,980
+Pregnancy أضف إلى ذلك ما يُعرف باسم الـ Intra
+
+327
+00:24:08,980 --> 00:24:13,960
+Uterine Device أي مانع الحمل المسمى اللولب اللولب
+
+328
+00:24:13,960 --> 00:24:19,420
+أو مانع الحمل بيسموه IUD Intra Uterine Device قد
+
+329
+00:24:19,420 --> 00:24:24,160
+يكون سبب أساسي من أسباب الـ Ectopic Pregnancy طبعا
+
+330
+00:24:24,160 --> 00:24:28,180
+بالنسبة إلى مانع الحمل يعتبر هو Safe ولكن يجب أن 
+
+331
+00:24:28,180 --> 00:24:32,780
+يحدث له عملية مراقبة مستمرة كل ثلاثة شهور إما Safe
+
+332
+00:24:32,780 --> 00:24:40,380
+أو من خلال طبيب بحد ذاته طبعا في عندي أنواع مختلفة
+
+333
+00:24:40,380 --> 00:24:45,140
+من ال IUD بعضهم بيعيش سنة وبعضهم بيعيش ستة وبعضهم
+
+334
+00:24:45,140 --> 00:24:48,580
+بيعيش عشر سنين بناء على طبيعته ولكن ال Mechanism
+
+335
+00:24:48,580 --> 00:24:53,560
+الأساسية الخاصة بكل نوع مختلفة فبعض الأنواع من
+
+336
+00:24:53,560 --> 00:24:57,680
+اللولب أو ال Intra-Uterine Device يفرز مواد
+
+337
+00:24:57,680 --> 00:25:01,760
+كيميائية تحفظ جهاز المناعة بما يؤدي إلى عمل
+
+338
+00:25:01,760 --> 00:25:07,560
+Engulfing للـ Spermatocyte يعني هدفه الأساسي هو
+
+339
+00:25:07,560 --> 00:25:12,600
+منع Spermatocyte اختراق منطقة الـ Cervix أو منطقة
+
+340
+00:25:12,600 --> 00:25:15,720
+اليوترا يعني منهم من الوصول إلى Fallopian tube
+
+341
+00:25:15,720 --> 00:25:20,500
+ففيه منه أنواع تفرز مواد كيميائية تحفظ بطانة الرحم
+
+342
+00:25:20,500 --> 00:25:24,900
+فبتخلي بطانة الرحم كإنها في مرحلة Inflammation مما
+
+343
+00:25:24,900 --> 00:25:29,460
+يؤدي إلى تقوية جهاز المناعة بوضخ جنوده من الـ
+
+344
+00:25:29,460 --> 00:25:34,100
+Engulfing Cells لمنطقة اليوترات فبتعمل Engulfing
+
+345
+00:25:34,100 --> 00:25:39,100
+للـ OO للـ Spermatocyte طريقة تانية أن بعضهم الآخر
+
+346
+00:25:39,100 --> 00:25:44,740
+بيفرس مواد Toxic تقتل الـ OO تقتل الـ Spermatocyte
+
+347
+00:25:44,740 --> 00:25:49,490
+إن تواجد في مناطق اليوترات Note that chance to
+
+348
+00:25:49,490 --> 00:25:51,950
+having successful pregnancy after Ectopic
+
+349
+00:25:51,950 --> 00:25:55,570
+Pregnancy may be reduced لأنها فقدت وفي عندها
+
+350
+00:25:55,570 --> 00:25:59,750
+احتمالية العودة لل Ectopic Pregnancy but this will
+
+351
+00:25:59,750 --> 00:26:03,610
+be depend on why that pregnancy was Ectopic and
+
+352
+00:26:03,610 --> 00:26:08,610
+what is your medical history فبالتالي أي سيدة
+
+353
+00:26:08,610 --> 00:26:12,630
+تتعرض لل Ectopic Pregnancy للمرة الأولى يجب مباشرة
+
+354
+00:26:12,630 --> 00:26:17,510
+متابعة الطبيب عند حدود حمل ثاني بشكل مباشر و بشكل
+
+355
+00:26:17,510 --> 00:26:21,230
+دوري ال Fallopian tube have been left in a place
+
+356
+00:26:21,230 --> 00:26:25,590
+you have approximately 60% chance to having
+
+357
+00:26:25,590 --> 00:26:30,590
+successful pregnancy لو قدر الله .. لو قدر الله
+
+358
+00:26:30,590 --> 00:26:34,130
+وصار عند السيدة Ectopic Pregnancy وصار في عندها
+
+359
+00:26:34,130 --> 00:26:40,630
+عملية جراحية أو أخدت أدوية أو صار 
+المناظر والتخلص
+
+360
+00:26:40,630 --> 00:26:43,670
+من ال Ectopic Pregnancy وباقية الـ Fallopian tube
+
+361
+00:26:43,670 --> 00:26:49,490
+على ما هي عليه تستطيع هذه السيدة أن تنجب بشكل
+
+362
+00:26:49,490 --> 00:26:54,310
+طبيعي بنسبة 60% في المستقبل خلّيني نشوف الفيديو
+
+363
+00:26:54,310 --> 00:26:58,030
+اللي بيتكلم عن ال Intra-Uterine Device وهو أحد
+
+364
+00:26:58,030 --> 00:27:02,110
+موانع الحمل المتحدث أو المتقدم به الأولى الدراسة
+
+365
+00:27:02,110 --> 00:27:06,890
+الانتجارية أو IUD هي طريقة تحكم الأطفال تتكون من
+
+366
+00:27:06,890 --> 00:27:10,570
+دراسة صغيرة ومتوسطة ومشكلة ومشكلة ومشكلة ومشكلة
+
+367
+00:27:10,570 --> 00:27:11,330
+ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة
+
+368
+00:27:11,330 --> 00:27:14,550
+ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة
+
+369
+00:27:14,550 --> 00:27:17,930
+ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة
+
+370
+00:27:17,930 --> 00:27:18,930
+ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة ومشكلة
+
+371
+00:27:18,930 --> 00:27:28,750
+ومشكلة ومشكلة ومشكلة ومشكلة
+
+372
+00:27:28,750 --> 00:27:33,370
+ومبتجارب كلا الـ IUD يسببان إلتهابا صغيرا من خلق
+
+373
+00:27:33,370 --> 00:27:38,970
+الـ uterine lining وهو يطرح جمعين محيطين ومخلوقات
+
+374
+00:27:38,970 --> 00:27:44,270
+يقتلوا الـ sperm IUD
+
+375
+00:27:44,270 --> 00:27:48,750
+الهرمونية تحتوي أيضا على نوع من البروجيسترون
+
+376
+00:27:48,750 --> 00:27:50,650
+الليفانورجسترال
+
+377
+00:27:52,150 --> 00:27:54,950
+Levonorgestrel mainly prevents pregnancy by
+
+378
+00:27:54,950 --> 00:27:57,650
+thickening the mucous inside the cervix, which
+
+379
+00:27:57,650 --> 00:28:00,930
+prevents sperm from entering the uterus. بعناها
+
+380
+00:28:00,930 --> 00:28:06,670
+بيحكيلي أن النوع الأول من اللولب بيعمل Induction
+
+381
+00:28:06,670 --> 00:28:10,630
+بيعمل Inducing لجهاز المناعة من ما يؤدي إلى جعل
+
+382
+00:28:10,630 --> 00:28:13,310
+جهاز المناعة يضف كمية كبيرة جدا من الـ Leukocytes
+
+383
+00:28:13,310 --> 00:28:18,030
+في المنطقة هذه، في مناطق الـ Uterus أما النوع
+
+384
+00:28:18,030 --> 00:28:21,170
+الثاني الخاص بالهرمونات يفرز مواد معينة تعمل على
+
+385
+00:28:21,170 --> 00:28:24,590
+زيادة ال Thickness تبع الـ Mucous وإذا بتتذكر قلنا
+
+386
+00:28:24,590 --> 00:28:28,550
+الـ Mucous يعتبر من أحد الحواجز التي تمنع وصول ال
+
+387
+00:28:28,550 --> 00:28:35,570
+Sperm إلى منطقة اليوترات أو قطع منطقة ال Cervix it
+
+388
+00:28:35,570 --> 00:28:38,290
+also prevents the Uterine lining from thickening
+
+389
+00:28:38,290 --> 00:28:41,410
+so it is less likely to receive a fertilized egg
+
+390
+00:28:45,910 --> 00:28:49,450
+قريبا من شهر بعد إدخال IUD، قد يقوم الدكتور
+
+391
+00:28:49,450 --> 00:28:54,390
+بإدخال تجارب للتأكد من أنها مازالت موجودة. قد يقوم
+
+392
+00:28:54,390 --> 00:28:58,010
+الدكتور أيضا بإعطاء الفتاة كيفية تحقق IUD بين
+
+393
+00:28:58,010 --> 00:29:03,810
+مقابلتها بشعور بالسطح في داخل الوجهة. بما يتعامل
+
+394
+00:29:03,810 --> 00:29:09,850
+مع الوضع، يمكن ترك IUD موجودة لـ 3 إلى 10 سنة. يمكن
+
+395
+00:29:09,850 --> 00:29:13,970
+أن يتحقق الدكتور من IUD في أي وقت، لأي سبب.
+
+396
+00:29:14,260 --> 00:29:20,880
+including the desire to have children An
+
+397
+00:29:20,880 --> 00:29:24,380
+Intrauterine device or IUD is one of the most
+
+398
+00:29:24,380 --> 00:29:29,240
+effective methods of birth control IUDs are over
+
+399
+00:29:29,240 --> 00:29:34,080
+99% effective at preventing pregnancy This means
+
+400
+00:29:34,080 --> 00:29:36,720
+that less than 1 out of 100 women will become
+
+401
+00:29:36,720 --> 00:29:40,280
+pregnant each year if they use an IUD and check it
+
+402
+00:29:40,280 --> 00:29:42,080
+regularly for correct placement
+
+403
+00:29:45,140 --> 00:29:49,620
+However, IUDs are only about 97% effective if not
+
+404
+00:29:49,620 --> 00:29:56,420
+checked for correct placement إذا 
+
+405
+00:29:56,420 --> 00:30:00,060
+المهم جدا في هذه العملية إنه يصير في عندي Recheck
+
+406
+00:30:00,060 --> 00:30:04,860
+بشكل شهري هل ال IUD في مكانه؟ هل ال IUD بيشتغل
+
+407
+00:30:04,860 --> 00:30:08,500
+بشكل طبيعي و بشكل سليم؟ ومافيش مشكلة إذا صار عملية
+
+408
+00:30:08,500 --> 00:30:11,620
+زيارة للطبيب كل فترة زمنها الـ 6 شهور، 4 شهور
+
+409
+00:30:11,620 --> 00:30:17,290
+علشان يتأكد من هذا الموضوع وفي بعض بعض التوصيات
+
+410
+00:30:17,290 --> 00:30:20,870
+تقول إنه ما في كمان مشكلة لو صار تغيير إليه كل سنة
+
+411
+00:30:20,870 --> 00:30:25,010
+كل سنتين بـ Device جديد هذا الخاص بالـ Ectopic
+
+412
+00:30:25,010 --> 00:30:29,750
+Pregnancy والـ IUD اللي أتكلمنا عنه أحد ال Risk
+
+413
+00:30:29,750 --> 00:30:34,770
+Factor الخاصة بالـ Ectopic Pregnancy لهذا الكم من
+
+414
+00:30:34,770 --> 00:30:38,470
+المعلومات و هذه المحاضرات المتتالية نقود قد أنهينا
+
+415
+00:30:38,470 --> 00:30:42,430
+من هذا ال Chapter نرجو من الله أن تكون متأمن بخير
+
+416
+00:30:42,430 --> 00:30:47,530
+على أمل أن نلتقي في أفضل الأوقات إن شاء الله دو دو
+
+417
+00:30:47,530 --> 00:30:47,790
+بخير
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/vcJ75dxZ2fw_raw.json b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/vcJ75dxZ2fw_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..c064db42a1ab56e694f08a1d72c3dd2382b2f767
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/vcJ75dxZ2fw_raw.json
@@ -0,0 +1 @@
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0.96826171875}, {"start": 18.77, "end": 19.35, "word": " المحاضرة", "probability": 0.9840087890625}, {"start": 19.35, "end": 20.87, "word": " السابقة", "probability": 0.9889322916666666}, {"start": 20.87, "end": 21.09, "word": " عن", "probability": 0.974609375}, {"start": 21.09, "end": 21.63, "word": " الأحداث", "probability": 0.9815673828125}, {"start": 21.63, "end": 21.91, "word": " التي", "probability": 0.806640625}, {"start": 21.91, "end": 23.07, "word": " تحدث", "probability": 0.95947265625}, {"start": 23.07, "end": 23.49, "word": " أثناء", "probability": 0.97119140625}, {"start": 23.49, "end": 23.87, "word": " عملية", "probability": 0.9871419270833334}, {"start": 23.87, "end": 24.03, "word": " ال", "probability": 0.9619140625}, {"start": 24.03, "end": 24.89, "word": " fertilization", "probability": 0.869384765625}, {"start": 24.89, "end": 26.37, "word": " توقفنا", "probability": 0.8778076171875}, {"start": 26.37, "end": 26.61, "word": " عند", "probability": 0.9658203125}, {"start": 26.61, "end": 27.11, "word": " مصطلح", "probability": 0.99287109375}, {"start": 27.11, "end": 27.51, "word": " مهم", "probability": 0.9873046875}, {"start": 27.51, "end": 28.07, "word": " وهو", "probability": 0.809326171875}, {"start": 28.07, "end": 28.69, "word": " عبارة", "probability": 0.991455078125}, {"start": 28.69, "end": 29.05, "word": " عن", "probability": 0.99658203125}, {"start": 29.05, "end": 30.05, "word": " عدم", "probability": 0.966064453125}], "temperature": 1.0}, {"id": 2, "seek": 5591, "start": 30.39, "end": 55.91, "text": "طلقيح البويضة بأكثر من نطفة بمعنى آخر مصطلح له أهمية كبيرة جدا مقصود فيه penetration of polyspermia أو polyspermia كيف بيصير عملية ال penetration؟ حكينا عنها بالتفصيل وشوفنا الفيديو اللي بتكلم عن عملية ال penetration و الفيديو تطرق إلى عملية منع", "tokens": [9566, 1211, 4587, 1829, 5016, 29739, 45865, 11242, 3660, 4724, 10721, 4117, 49115, 9154, 8717, 9566, 5172, 3660, 4724, 2304, 3615, 1863, 7578, 19753, 34740, 3714, 9381, 9566, 1211, 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"end": 33.55, "word": " نطفة", "probability": 0.968017578125}, {"start": 33.55, "end": 34.41, "word": " بمعنى", "probability": 0.8982421875}, {"start": 34.41, "end": 34.93, "word": " آخر", "probability": 0.873046875}, {"start": 34.93, "end": 36.09, "word": " مصطلح", "probability": 0.920703125}, {"start": 36.09, "end": 37.29, "word": " له", "probability": 0.96923828125}, {"start": 37.29, "end": 37.93, "word": " أهمية", "probability": 0.9778645833333334}, {"start": 37.93, "end": 38.33, "word": " كبيرة", "probability": 0.9791666666666666}, {"start": 38.33, "end": 38.73, "word": " جدا", "probability": 0.952880859375}, {"start": 38.73, "end": 39.59, "word": " مقصود", "probability": 0.8653564453125}, {"start": 39.59, "end": 39.99, "word": " فيه", "probability": 0.788818359375}, {"start": 39.99, "end": 40.75, "word": " penetration", "probability": 0.253173828125}, {"start": 40.75, "end": 41.33, "word": " of", "probability": 0.97802734375}, {"start": 41.33, "end": 42.25, "word": " 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"probability": 0.867919921875}, {"start": 51.37, "end": 51.47, "word": " اللي", "probability": 0.904052734375}, {"start": 51.47, "end": 51.89, "word": " بتكلم", "probability": 0.8868815104166666}, {"start": 51.89, "end": 52.11, "word": " عن", "probability": 0.9765625}, {"start": 52.11, "end": 52.43, "word": " عملية", "probability": 0.9833984375}, {"start": 52.43, "end": 52.59, "word": " ال", "probability": 0.97216796875}, {"start": 52.59, "end": 53.07, "word": " penetration", "probability": 0.98681640625}, {"start": 53.07, "end": 53.39, "word": " و", "probability": 0.72021484375}, {"start": 53.39, "end": 53.79, "word": " الفيديو", "probability": 0.9462890625}, {"start": 53.79, "end": 54.33, "word": " تطرق", "probability": 0.857421875}, {"start": 54.33, "end": 54.55, "word": " إلى", "probability": 0.77783203125}, {"start": 54.55, "end": 55.27, "word": " عملية", "probability": 0.9855143229166666}, {"start": 55.27, "end": 55.91, "word": " منع", "probability": 0.829345703125}], "temperature": 1.0}, {"id": 3, "seek": 8417, "start": 56.33, "end": 84.17, "text": "التلقيح البويضة بحيوان منوي آخر إن تم تلقيحها في مصابق مصطلح مهم جدا هتتكلم عنه وهو عبارة of prevention of polyspermia ومصطلح آخر اسمهectopic pregnancy كحالة مرضية تتعرض له السيدة طبعا بمجرد حدوث fusion للـ sperm ودخوله واختراقه الـ zoonabucida برقم SZP3", "tokens": [6027, 2655, 1211, 38436, 5016, 29739, 45865, 11242, 3660, 4724, 5016, 1829, 2407, 7649, 9154, 45865, 19753, 34740, 36145, 46811, 6055, 1211, 38436, 5016, 11296, 8978, 3714, 9381, 16758, 4587, 3714, 9381, 9566, 1211, 5016, 3714, 16095, 10874, 28259, 8032, 2655, 2655, 4117, 19528, 18871, 3224, 37037, 2407, 6225, 3555, 9640, 3660, 295, 659, 553, 83, 313, 295, 6754, 82, 610, 29958, 4032, 2304, 9381, 9566, 1211, 5016, 19753, 34740, 24525, 2304, 3224, 557, 40216, 16120, 9122, 5016, 6027, 3660, 3714, 43042, 10632, 6055, 2655, 3615, 43042, 46740, 21136, 25708, 3660, 23032, 3555, 3615, 995, 4724, 2304, 7435, 2288, 3215, 11331, 3215, 2407, 12984, 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76.95, "word": " fusion", "probability": 0.55419921875}, {"start": 76.95, "end": 77.83, "word": " للـ", "probability": 0.430908203125}, {"start": 77.83, "end": 78.25, "word": " sperm", "probability": 0.56005859375}, {"start": 78.25, "end": 79.89, "word": " ودخوله", "probability": 0.97685546875}, {"start": 79.89, "end": 80.87, "word": " واختراقه", "probability": 0.9588216145833334}, {"start": 80.87, "end": 80.99, "word": " الـ", "probability": 0.7392578125}, {"start": 80.99, "end": 81.65, "word": " zoonabucida", "probability": 0.4677490234375}, {"start": 81.65, "end": 82.61, "word": " برقم", "probability": 0.9688720703125}, {"start": 82.61, "end": 84.17, "word": " SZP3", "probability": 0.80322265625}], "temperature": 1.0}, {"id": 4, "seek": 11055, "start": 85.17, "end": 110.55, "text": "تدخل المادة الوراثية الخاصة بالـ sperm وتندمج مع المادة الوراثية الخاصة بالـ oocyte لتجوين الـ zygote ولكن قبل عملية الاندماج اللي يجب أن يحدث هناك بعض التغييرات على السطح الخارجي للبوايضة يمنع اختراقها بother sperm تحت مسمة «prevention of polyspermia» كيف عملية الـ «prevention» بتصير؟", "tokens": [2655, 3215, 9778, 1211, 9673, 18513, 3660, 2423, 13063, 5718, 104, 10632, 33962, 33546, 3660, 20666, 39184, 32899, 34683, 1863, 40448, 7435, 20449, 9673, 18513, 3660, 2423, 13063, 5718, 104, 10632, 33962, 33546, 3660, 20666, 39184, 277, 31078, 975, 5296, 2655, 7435, 2407, 9957, 2423, 39184, 710, 18103, 1370, 35525, 19452, 12174, 36150, 6225, 42213, 10632, 2423, 7649, 40448, 26108, 13672, 1829, 7251, 7435, 3555, 14739, 7251, 24401, 12984, 34105, 4117, 45030, 11242, 16712, 17082, 1829, 13546, 9307, 15844, 21136, 9566, 5016, 33962, 9640, 7435, 1829, 24976, 3555, 14407, 1829, 11242, 3660, 7251, 27842, 3615, 1975, 46456, 23557, 4587, 11296, 4724, 802, 32899, 6055, 33753, 3714, 38251, 3660, 4657, 3712, 2475, 313, 295, 6754, 82, 610, 29958, 5933, 9122, 33911, 6225, 42213, 10632, 2423, 39184, 4657, 3712, 2475, 313, 5933, 39894, 9381, 13546, 22807], "avg_logprob": -0.16319445062566687, 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563.25, "word": " تانية", "probability": 0.9073893229166666}, {"start": 563.25, "end": 564.45, "word": " مع", "probability": 0.91259765625}, {"start": 564.45, "end": 564.93, "word": " بعض", "probability": 0.96826171875}, {"start": 564.93, "end": 565.51, "word": " التأكيد", "probability": 0.8626708984375}], "temperature": 1.0}, {"id": 21, "seek": 58438, "start": 567.34, "end": 584.38, "text": "خلّيني أتفرج عليها دي دخل الـ sperm عامل penetration صار انتفاف البويضة بفعل إفراز الـ polysaccharide وإفراز الـ lytic enzyme هذا بالنسبة لعملية ال blocking كيف تمنع البويضة نفسها من التلقيه في sperm آخر", "tokens": [9778, 1211, 11703, 9957, 1829, 5551, 2655, 5172, 47341, 25894, 11296, 11778, 1829, 11778, 9778, 1211, 2423, 39184, 32899, 6225, 10943, 1211, 35187, 20328, 9640, 16472, 2655, 5172, 31845, 29739, 45865, 11242, 3660, 4724, 5172, 30241, 11933, 5172, 2288, 31377, 2423, 39184, 6754, 82, 326, 7374, 482, 4032, 28814, 5172, 2288, 31377, 2423, 39184, 287, 43658, 24521, 23758, 20666, 1863, 35457, 3660, 5296, 25957, 1211, 10632, 2423, 17776, 9122, 33911, 6055, 27842, 3615, 29739, 45865, 11242, 3660, 8717, 36178, 11296, 9154, 16712, 1211, 38436, 3224, 8978, 32899, 19753, 34740], "avg_logprob": -0.24618054843611187, "compression_ratio": 1.4976525821596245, "no_speech_prob": 3.0994415283203125e-06, "words": [{"start": 567.34, "end": 567.68, "word": "خلّيني", "probability": 0.7540771484375}, {"start": 567.68, "end": 568.06, "word": " أتفرج", "probability": 0.86328125}, {"start": 568.06, "end": 568.38, "word": " عليها", "probability": 0.856689453125}, {"start": 568.38, "end": 568.98, "word": " دي", "probability": 0.93310546875}, {"start": 568.98, "end": 569.38, "word": " دخل", "probability": 0.7794596354166666}, {"start": 569.38, "end": 569.58, "word": " الـ", "probability": 0.689697265625}, {"start": 569.58, "end": 569.8, "word": " sperm", "probability": 0.2900390625}, {"start": 569.8, "end": 570.02, "word": " عامل", "probability": 0.5509440104166666}, {"start": 570.02, "end": 570.48, "word": " penetration", "probability": 0.7685546875}, {"start": 570.48, "end": 571.1, "word": " صار", "probability": 0.81103515625}, {"start": 571.1, "end": 571.52, "word": " انتفاف", "probability": 0.760498046875}, {"start": 571.52, "end": 571.98, "word": " البويضة", "probability": 0.8350830078125}, {"start": 571.98, "end": 572.34, "word": " بفعل", "probability": 0.8645833333333334}, {"start": 572.34, "end": 572.7, "word": " إفراز", "probability": 0.9310302734375}, {"start": 572.7, "end": 572.88, "word": " الـ", "probability": 0.594970703125}, {"start": 572.88, "end": 573.5, "word": " polysaccharide", "probability": 0.934375}, {"start": 573.5, "end": 574.58, "word": " وإفراز", "probability": 0.85380859375}, {"start": 574.58, "end": 574.88, "word": " الـ", "probability": 0.55517578125}, {"start": 574.88, "end": 575.04, "word": " lytic", "probability": 0.753662109375}, {"start": 575.04, "end": 575.44, "word": " enzyme", "probability": 0.89111328125}, {"start": 575.44, "end": 576.02, "word": " هذا", "probability": 0.75732421875}, {"start": 576.02, "end": 576.72, "word": " بالنسبة", "probability": 0.9927978515625}, {"start": 576.72, "end": 578.12, "word": " لعملية", "probability": 0.961669921875}, {"start": 578.12, "end": 578.3, "word": " ال", "probability": 0.83203125}, {"start": 578.3, "end": 578.72, "word": " blocking", "probability": 0.716796875}, {"start": 578.72, "end": 579.84, "word": " كيف", "probability": 0.936279296875}, {"start": 579.84, "end": 580.74, "word": " تمنع", "probability": 0.8435872395833334}, {"start": 580.74, "end": 581.32, "word": " البويضة", "probability": 0.9886474609375}, {"start": 581.32, "end": 581.86, "word": " نفسها", "probability": 0.99072265625}, {"start": 581.86, "end": 582.08, "word": " من", "probability": 0.9951171875}, {"start": 582.08, "end": 582.72, "word": " التلقيه", "probability": 0.649658203125}, {"start": 582.72, "end": 582.86, "word": " في", "probability": 0.37353515625}, {"start": 582.86, "end": 583.26, "word": " sperm", "probability": 0.97607421875}, {"start": 583.26, "end": 584.38, "word": " آخر", "probability": 0.85107421875}], "temperature": 1.0}, {"id": 22, "seek": 60567, "start": 585.68, "end": 605.68, "text": "بالتالي، بعد بنتراجن من الـ Oocyte إلى الـ spermatozoon من خلال الـ spermatozoon بالتأكيد، نكولة الـ Oocyte يجب أن تتفجر مع نكولة الـ sperm ولكن قبل أن يحدث التفجير، يجب أن يكتمل انقسام الميوزي الثاني لأن البوايضة تتوقفت في الـ Metaphase II", "tokens": [3555, 6027, 2655, 6027, 1829, 12399, 39182, 44945, 2655, 2288, 26108, 1863, 9154, 2423, 39184, 422, 31078, 975, 30731, 2423, 39184, 32899, 2513, 89, 4106, 9154, 16490, 1211, 6027, 2423, 39184, 32899, 2513, 89, 4106, 20666, 2655, 10721, 4117, 25708, 12399, 8717, 4117, 12610, 3660, 2423, 39184, 422, 31078, 975, 7251, 7435, 3555, 14739, 6055, 2655, 5172, 7435, 2288, 20449, 8717, 4117, 12610, 3660, 2423, 39184, 32899, 35525, 19452, 12174, 36150, 14739, 7251, 24401, 12984, 16712, 5172, 7435, 13546, 12399, 7251, 7435, 3555, 14739, 7251, 4117, 39237, 1211, 16472, 4587, 3794, 10943, 9673, 1829, 2407, 11622, 1829, 6024, 104, 7649, 1829, 5296, 33456, 29739, 14407, 1829, 11242, 3660, 6055, 2655, 30543, 5172, 2655, 8978, 2423, 39184, 6377, 13957, 651, 6351], "avg_logprob": -0.42407024990428577, "compression_ratio": 1.759090909090909, "no_speech_prob": 4.76837158203125e-07, "words": [{"start": 585.68, "end": 586.04, "word": "بالتالي،", "probability": 0.5998331705729166}, {"start": 586.04, "end": 586.04, "word": " بعد", "probability": 0.8349609375}, {"start": 586.04, "end": 586.68, "word": " بنتراجن", "probability": 0.677783203125}, {"start": 586.68, "end": 586.94, "word": " من", "probability": 0.37353515625}, {"start": 586.94, "end": 587.14, "word": " الـ", "probability": 0.465087890625}, {"start": 587.14, "end": 587.76, "word": " Oocyte", "probability": 0.7635904947916666}, {"start": 587.76, "end": 587.98, "word": " إلى", "probability": 0.1275634765625}, {"start": 587.98, "end": 588.06, "word": " الـ", "probability": 0.733642578125}, {"start": 588.06, "end": 588.76, "word": " spermatozoon", "probability": 0.67578125}, {"start": 588.76, "end": 589.46, "word": " من", "probability": 0.280517578125}, {"start": 589.46, "end": 589.48, "word": " خلال", "probability": 0.7277018229166666}, {"start": 589.48, "end": 589.62, "word": " الـ", "probability": 0.4814453125}, {"start": 589.62, "end": 590.24, "word": " spermatozoon", "probability": 0.9415283203125}, {"start": 590.24, "end": 590.98, "word": " بالتأكيد،", "probability": 0.6765543619791666}, {"start": 590.98, "end": 591.62, "word": " نكولة", "probability": 0.4620361328125}, {"start": 591.62, "end": 591.78, "word": " الـ", "probability": 0.82763671875}, {"start": 591.78, "end": 592.42, "word": " Oocyte", "probability": 0.8805338541666666}, {"start": 592.42, "end": 592.94, "word": " يجب", "probability": 0.7383626302083334}, {"start": 592.94, "end": 593.08, "word": " أن", "probability": 0.70849609375}, {"start": 593.08, "end": 594.04, "word": " تتفجر", "probability": 0.552001953125}, {"start": 594.04, "end": 594.3, "word": " مع", "probability": 0.77587890625}, {"start": 594.3, "end": 595.44, "word": " نكولة", "probability": 0.9822998046875}, {"start": 595.44, "end": 595.84, "word": " الـ", "probability": 0.806884765625}, {"start": 595.84, "end": 596.74, "word": " sperm", "probability": 0.92626953125}, {"start": 596.74, "end": 597.44, "word": " ولكن", "probability": 0.7109375}, {"start": 597.44, "end": 597.66, "word": " قبل", "probability": 0.84423828125}, {"start": 597.66, "end": 597.82, "word": " أن", "probability": 0.60888671875}, {"start": 597.82, "end": 598.0, "word": " يحدث", "probability": 0.6753743489583334}, {"start": 598.0, "end": 598.5, "word": " التفجير،", "probability": 0.8548828125}, {"start": 598.5, "end": 598.7, "word": " يجب", "probability": 0.9401041666666666}, {"start": 598.7, "end": 598.8, "word": " أن", "probability": 0.67626953125}, {"start": 598.8, "end": 599.46, "word": " يكتمل", "probability": 0.777191162109375}, {"start": 599.46, "end": 600.08, "word": " انقسام", "probability": 0.745513916015625}, {"start": 600.08, "end": 600.98, "word": " الميوزي", "probability": 0.92529296875}, {"start": 600.98, "end": 601.56, "word": " الثاني", "probability": 0.910400390625}, {"start": 601.56, "end": 602.2, "word": " لأن", "probability": 0.8193359375}, {"start": 602.2, "end": 602.7, "word": " البوايضة", "probability": 0.631201171875}, {"start": 602.7, "end": 603.9, "word": " تتوقفت", "probability": 0.76025390625}, {"start": 603.9, "end": 604.54, "word": " في", "probability": 0.916015625}, {"start": 604.54, "end": 604.82, "word": " الـ", "probability": 0.666748046875}, {"start": 604.82, "end": 605.38, "word": " Metaphase", "probability": 0.6763509114583334}, {"start": 605.38, "end": 605.68, "word": " II", "probability": 0.400634765625}], "temperature": 1.0}, {"id": 23, "seek": 63671, "start": 607.11, "end": 636.71, "text": "اكتمال انقسام الميوز التاني، ظهور الـ second polar body في منطقات الـ pre-deline space.Cytoplasmic factors control the growth of female and male pronuclear.البرونيوكلر تظهر بعد الإخصاف ب6 إلى 8 ساعات كحد أدنى and they continuous for approximately 10 to 12 hours.يعني هذه البرونيوكلر تظهر بعد عملية ال penetration ب8 ساعات كحد أدنى", "tokens": [995, 4117, 39237, 6027, 16472, 4587, 3794, 10943, 9673, 1829, 2407, 11622, 16712, 7649, 1829, 12399, 1357, 116, 3224, 13063, 2423, 39184, 1150, 12367, 1772, 8978, 9154, 9566, 4587, 9307, 2423, 39184, 659, 12, 67, 5440, 1901, 13, 34, 4328, 404, 7743, 13195, 6771, 1969, 264, 4599, 295, 6556, 293, 7133, 7569, 30335, 13, 6027, 26890, 11536, 1829, 2407, 28820, 2288, 6055, 19913, 3224, 2288, 39182, 33688, 9778, 9381, 31845, 4724, 21, 30731, 1649, 8608, 45761, 9307, 9122, 24401, 5551, 3215, 1863, 7578, 293, 436, 10957, 337, 10447, 1266, 281, 2272, 2496, 13, 40228, 22653, 29538, 2423, 26890, 11536, 1829, 2407, 28820, 2288, 6055, 19913, 3224, 2288, 39182, 6225, 42213, 10632, 2423, 35187, 4724, 23, 8608, 45761, 9307, 9122, 24401, 5551, 3215, 1863, 7578], "avg_logprob": -0.2549999933242798, "compression_ratio": 1.577319587628866, "no_speech_prob": 0.0, "words": [{"start": 607.11, "end": 607.75, "word": "اكتمال", "probability": 0.70355224609375}, {"start": 607.75, "end": 608.39, "word": " انقسام", "probability": 0.799560546875}, {"start": 608.39, "end": 608.83, "word": " الميوز", "probability": 0.8297119140625}, {"start": 608.83, "end": 609.45, "word": " التاني،", "probability": 0.74951171875}, {"start": 609.45, "end": 609.81, "word": " ظهور", "probability": 0.88720703125}, {"start": 609.81, "end": 610.11, "word": " الـ", "probability": 0.829833984375}, {"start": 610.11, "end": 610.33, "word": " second", "probability": 0.259033203125}, {"start": 610.33, "end": 610.77, "word": " polar", "probability": 0.85693359375}, {"start": 610.77, "end": 611.21, "word": " body", "probability": 0.8720703125}, {"start": 611.21, "end": 611.53, "word": " في", "probability": 0.8720703125}, {"start": 611.53, "end": 612.03, "word": " منطقات", "probability": 0.7203369140625}, {"start": 612.03, "end": 612.27, "word": " الـ", "probability": 0.941162109375}, {"start": 612.27, "end": 612.49, "word": " pre", "probability": 0.74169921875}, {"start": 612.49, "end": 613.31, "word": "-deline", "probability": 0.3475138346354167}, {"start": 613.31, "end": 613.79, "word": " space", "probability": 0.7666015625}, {"start": 613.79, "end": 614.93, "word": ".Cytoplasmic", "probability": 0.6867777506510416}, {"start": 614.93, "end": 615.57, "word": " factors", "probability": 0.87744140625}, {"start": 615.57, "end": 616.45, "word": " control", "probability": 0.8173828125}, {"start": 616.45, "end": 616.77, "word": " the", "probability": 0.91162109375}, {"start": 616.77, "end": 617.09, "word": " growth", "probability": 0.93310546875}, {"start": 617.09, "end": 617.47, "word": " of", "probability": 0.97802734375}, {"start": 617.47, "end": 617.87, "word": " female", "probability": 0.76513671875}, {"start": 617.87, "end": 618.57, "word": " and", "probability": 0.9580078125}, {"start": 618.57, "end": 618.99, "word": " male", "probability": 0.89990234375}, {"start": 618.99, "end": 619.67, "word": " pronuclear", "probability": 0.829345703125}, {"start": 619.67, "end": 620.83, "word": ".البرونيوكلر", "probability": 0.7830810546875}, {"start": 620.83, "end": 621.49, "word": " تظهر", "probability": 0.9951171875}, {"start": 621.49, "end": 621.79, "word": " بعد", "probability": 0.96044921875}, {"start": 621.79, "end": 622.33, "word": " الإخصاف", "probability": 0.7916259765625}, {"start": 622.33, "end": 623.09, "word": " ب6", "probability": 0.738037109375}, {"start": 623.09, "end": 623.67, "word": " إلى", "probability": 0.8662109375}, {"start": 623.67, "end": 624.13, "word": " 8", "probability": 0.97900390625}, {"start": 624.13, "end": 624.87, "word": " ساعات", "probability": 0.97412109375}, {"start": 624.87, "end": 625.37, "word": " كحد", "probability": 0.748291015625}, {"start": 625.37, "end": 626.21, "word": " أدنى", "probability": 0.8837890625}, {"start": 626.21, "end": 626.67, "word": " and", "probability": 0.583984375}, {"start": 626.67, "end": 626.79, "word": " they", "probability": 0.87548828125}, {"start": 626.79, "end": 627.29, "word": " continuous", "probability": 0.447998046875}, {"start": 627.29, "end": 627.93, "word": " for", "probability": 0.9609375}, {"start": 627.93, "end": 628.51, "word": " approximately", "probability": 0.80419921875}, {"start": 628.51, "end": 629.25, "word": " 10", "probability": 0.92919921875}, {"start": 629.25, "end": 629.39, "word": " to", "probability": 0.80517578125}, {"start": 629.39, "end": 629.75, "word": " 12", "probability": 0.96337890625}, {"start": 629.75, "end": 630.25, "word": " hours", "probability": 0.7939453125}, {"start": 630.25, "end": 631.15, "word": ".يعني", "probability": 0.75146484375}, {"start": 631.15, "end": 631.91, "word": " هذه", "probability": 0.218017578125}, {"start": 631.91, "end": 632.67, "word": " 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chromosome will be fusion علشان يكوّل مراكب جديد بنسمي الزيجوت يعني بمعنى أخر الزيجوت هي عبارة عن محصلة اندماج النواة الذكرية اللي كانت", "tokens": [2407, 6055, 3555, 4587, 7578, 9122, 15042, 39896, 5296, 2304, 41891, 2272, 8608, 995, 27884, 9122, 24401, 5551, 4587, 9381, 7578, 562, 264, 7133, 293, 6556, 7569, 30335, 808, 666, 3385, 641, 19651, 18188, 293, 264, 42896, 486, 312, 23100, 11203, 8592, 7649, 7251, 4117, 2407, 11703, 1211, 3714, 23557, 4117, 3555, 10874, 16254, 3215, 44945, 38251, 1829, 6024, 110, 1829, 7435, 35473, 37495, 22653, 4724, 2304, 3615, 1863, 7578, 5551, 34740, 6024, 110, 1829, 7435, 35473, 39896, 6225, 3555, 9640, 3660, 18871, 3714, 5016, 36520, 3660, 16472, 40448, 26108, 28239, 14407, 3660, 32545, 4117, 16572, 3660, 13672, 1829, 25961, 2655], "avg_logprob": -0.23238358018445035, "compression_ratio": 1.4552529182879377, "no_speech_prob": 2.6226043701171875e-06, "words": [{"start": 637.08, "end": 637.28, "word": "و", "probability": 0.505859375}, {"start": 637.28, 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"probability": 0.898046875}, {"start": 1817.29, "end": 1817.55, "word": " تقول", "probability": 0.6251220703125}, {"start": 1817.55, "end": 1818.03, "word": " إنه", "probability": 0.578125}, {"start": 1818.03, "end": 1818.17, "word": " ما", "probability": 0.71875}, {"start": 1818.17, "end": 1818.37, "word": " في", "probability": 0.61865234375}, {"start": 1818.37, "end": 1818.63, "word": " كمان", "probability": 0.8169759114583334}, {"start": 1818.63, "end": 1819.01, "word": " مشكلة", "probability": 0.9793294270833334}, {"start": 1819.01, "end": 1819.17, "word": " لو", "probability": 0.89892578125}, {"start": 1819.17, "end": 1819.39, "word": " صار", "probability": 0.8486328125}, {"start": 1819.39, "end": 1820.09, "word": " تغيير", "probability": 0.9693603515625}, {"start": 1820.09, "end": 1820.49, "word": " إليه", "probability": 0.54248046875}, {"start": 1820.49, "end": 1820.65, "word": " كل", "probability": 0.96630859375}, {"start": 1820.65, "end": 1820.87, "word": " سنة", "probability": 0.98486328125}, {"start": 1820.87, "end": 1821.05, "word": " كل", "probability": 0.189697265625}, {"start": 1821.05, "end": 1821.57, "word": " سنتين", "probability": 0.9959309895833334}, {"start": 1821.57, "end": 1822.13, "word": " ب", "probability": 0.7568359375}, {"start": 1822.13, "end": 1822.87, "word": " device", "probability": 0.59326171875}, {"start": 1822.87, "end": 1823.67, "word": " جديد", "probability": 0.9793294270833334}, {"start": 1823.67, "end": 1824.15, "word": " هذا", "probability": 0.86865234375}, {"start": 1824.15, "end": 1824.53, "word": " الخاص", "probability": 0.951171875}, {"start": 1824.53, "end": 1824.75, "word": " بالـ", "probability": 0.822265625}, {"start": 1824.75, "end": 1825.01, "word": " Octopic", "probability": 0.4686279296875}, {"start": 1825.01, "end": 1825.67, "word": " Pregnancy", "probability": 0.9093017578125}, {"start": 1825.67, "end": 1826.95, "word": " والـ", "probability": 0.4752197265625}, {"start": 1826.95, "end": 1827.71, "word": " IUD", "probability": 0.794921875}, {"start": 1827.71, "end": 1828.21, "word": " اللي", "probability": 0.67578125}, {"start": 1828.21, "end": 1828.65, "word": " أتكلمنا", "probability": 0.741357421875}, {"start": 1828.65, "end": 1828.95, "word": " عنه", "probability": 0.993408203125}, {"start": 1828.95, "end": 1829.31, "word": " أحد", "probability": 0.968017578125}, {"start": 1829.31, "end": 1829.57, "word": " ال", "probability": 0.935546875}, {"start": 1829.57, "end": 1829.75, "word": " risk", "probability": 0.72314453125}, {"start": 1829.75, "end": 1830.27, "word": " factor", "probability": 0.55078125}, {"start": 1830.27, "end": 1831.45, "word": " الخاصة", "probability": 0.9318033854166666}, {"start": 1831.45, "end": 1832.55, "word": " بالـ", "probability": 0.888427734375}, {"start": 1832.55, "end": 1832.89, "word": " Octopic", "probability": 0.877685546875}, {"start": 1832.89, "end": 1833.51, "word": " Pregnancy", "probability": 0.968505859375}, {"start": 1833.51, "end": 1834.39, "word": " لهذا", "probability": 0.6102294921875}, {"start": 1834.39, "end": 1834.61, "word": " الكم", "probability": 0.692626953125}, {"start": 1834.61, "end": 1834.77, "word": " من", "probability": 0.99609375}, {"start": 1834.77, "end": 1835.37, "word": " المعلومات", "probability": 0.9908447265625}, {"start": 1835.37, "end": 1835.49, "word": " و", "probability": 0.62451171875}, {"start": 1835.49, "end": 1835.75, "word": " هذه", "probability": 0.630859375}, {"start": 1835.75, "end": 1836.37, "word": " المحاضرات", "probability": 0.94775390625}, {"start": 1836.37, "end": 1837.07, "word": " المتتالية", "probability": 0.98974609375}, {"start": 1837.07, "end": 1837.69, "word": " نقود", "probability": 0.8899739583333334}, {"start": 1837.69, "end": 1837.99, "word": " قد", "probability": 0.984375}, {"start": 1837.99, "end": 1838.47, "word": " أنهينا", "probability": 0.940185546875}, {"start": 1838.47, "end": 1838.63, "word": " من", "probability": 0.98095703125}, {"start": 1838.63, "end": 1838.87, "word": " هذا", "probability": 0.98388671875}, {"start": 1838.87, "end": 1839.01, "word": " ال", "probability": 0.71630859375}, {"start": 1839.01, "end": 1839.33, "word": " chapter", "probability": 0.70751953125}, {"start": 1839.33, "end": 1840.95, "word": " نرجو", "probability": 0.8966471354166666}, {"start": 1840.95, "end": 1841.11, "word": " من", "probability": 0.904296875}, {"start": 1841.11, "end": 1841.25, "word": " الله", "probability": 0.951171875}, {"start": 1841.25, "end": 1841.39, "word": " أن", "probability": 0.88037109375}, {"start": 1841.39, "end": 1841.65, "word": " تكون", "probability": 0.965576171875}, {"start": 1841.65, "end": 1842.01, "word": " متأمن", "probability": 0.611328125}, {"start": 1842.01, "end": 1842.43, "word": " بخير", "probability": 0.9874674479166666}, {"start": 1842.43, "end": 1842.61, "word": " على", "probability": 0.9111328125}, {"start": 1842.61, "end": 1842.89, "word": " أمل", "probability": 0.92431640625}, {"start": 1842.89, "end": 1843.11, "word": " أن", "probability": 0.9365234375}, {"start": 1843.11, "end": 1843.59, "word": " نلتقي", "probability": 0.976318359375}, {"start": 1843.59, "end": 1843.99, "word": " في", "probability": 0.9345703125}, {"start": 1843.99, "end": 1844.55, "word": " أفضل", "probability": 0.99560546875}], "temperature": 1.0}, {"id": 70, "seek": 184779, "start": 1845.89, "end": 1847.79, "text": "الأوقات ان شاء الله دو دو بخي", "tokens": [6027, 10721, 30543, 9307, 16472, 13412, 16606, 21984, 11778, 2407, 11778, 2407, 4724, 9778, 1829], "avg_logprob": -0.23608398623764515, "compression_ratio": 1.0, "no_speech_prob": 0.0, "words": [{"start": 1845.89, "end": 1846.41, "word": "الأوقات", "probability": 0.85205078125}, {"start": 1846.41, "end": 1846.51, "word": " ان", "probability": 0.75244140625}, {"start": 1846.51, "end": 1846.75, "word": " شاء", "probability": 0.980224609375}, {"start": 1846.75, "end": 1847.09, "word": " الله", "probability": 0.9599609375}, {"start": 1847.09, "end": 1847.41, "word": " دو", "probability": 0.65283203125}, {"start": 1847.41, "end": 1847.53, "word": " دو", "probability": 0.83935546875}, {"start": 1847.53, "end": 1847.79, "word": " بخي", "probability": 0.6954752604166666}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 1889.2219375, "duration_after_vad": 1783.0462499999944}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/wi8cqG8vR_Q_raw.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/wi8cqG8vR_Q_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..0b56cc1e04332e0e5d20cb94e369e8adf9c64a2b
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/wi8cqG8vR_Q_raw.srt
@@ -0,0 +1,1980 @@
+1
+00:00:00,790 --> 00:00:04,650
+باسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:04,650 --> 00:00:10,210
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين اليوم
+
+3
+00:00:10,210 --> 00:00:14,230
+سوف نستكمل الجزء الأخير من هذا ال chapter والذي
+
+4
+00:00:14,230 --> 00:00:19,850
+سوف يتكلم بشكل أساسي عن ال culture media بمعنى ما
+
+5
+00:00:19,850 --> 00:00:24,350
+هي الأوساط التي يمكن أن تستخدم خلال عملية التلقيح
+
+6
+00:00:24,350 --> 00:00:28,980
+الصناعيما هي الأوساط التي يمكن أن تستخدم خلال نضوج
+
+7
+00:00:28,980 --> 00:00:33,800
+وانضاج البويضات خارج الرحم وما هي مكونات هذه
+
+8
+00:00:33,800 --> 00:00:39,080
+الأوساط وما هي الهدف الأساسي من استخدام هذه
+
+9
+00:00:39,080 --> 00:00:43,840
+المكونات ال culture media بشكل عام هي عبارة عن وسط
+
+10
+00:00:43,840 --> 00:00:48,360
+غذائي يشبه وسط الغذاء التي تكون متواجدة فيه
+
+11
+00:00:48,360 --> 00:00:52,400
+البويضة وتستخدم يا إما من أجل إنماء البويضة
+
+12
+00:00:52,610 --> 00:00:57,150
+واستكمال نموها إذا كانت في مرحة الـ M1 أو إبقائها
+
+13
+00:00:57,150 --> 00:01:02,350
+في وسط طبيعي يشبه الوسط الذي سوف تنتقل إليه وهو
+
+14
+00:01:02,350 --> 00:01:07,370
+عبارة عن رحم السيدة خلال عملية ال injection The
+
+15
+00:01:07,370 --> 00:01:11,390
+optimal cultural media which reflect the changing
+
+16
+00:01:11,390 --> 00:01:17,770
+need of the developed embryo is important for
+
+17
+00:01:17,770 --> 00:01:23,260
+success of IVF treatmentيعني بمعنى آخر كل ما كانت
+
+18
+00:01:23,260 --> 00:01:29,880
+الوسط الزراعي أو ال media قريبة من الوسط التي يوجد
+
+19
+00:01:29,880 --> 00:01:35,080
+فيه ال embryo أو توجد فيه البويضة كل ما زاد فرصة
+
+20
+00:01:35,080 --> 00:01:39,040
+نجاح عملية التلقيح أو عملية الحقن المجاني ال
+
+21
+00:01:39,040 --> 00:01:44,660
+environment بتلعب دور مهم جداالضغط الشديد اللى
+
+22
+00:01:44,660 --> 00:01:48,160
+بتتعرضلها الخلية بتتعرضل الـ oocyte من oxidative
+
+23
+00:01:48,160 --> 00:01:52,200
+stress من pH من كمية البومين من كمية البروتين من
+
+24
+00:01:52,200 --> 00:01:56,280
+كمية الجلوكوز من كمية البيروفيت يجب أن تشبه إلى حد
+
+25
+00:01:56,280 --> 00:02:00,480
+ما الكمية اللى بتتعرضلها و هي في ال ovary و هي في
+
+26
+00:02:00,480 --> 00:02:05,580
+ال uterus و هي كمان في ال fallopian tube فمش هيكون
+
+27
+00:02:05,580 --> 00:02:10,760
+هناك اختلاف لضمان نجاح عملية الحقن المجهري سواء
+
+28
+00:02:10,760 --> 00:02:15,370
+كانت البويضةفي مرحلة بويضة أو في مرحلة زيجوت أو في
+
+29
+00:02:15,370 --> 00:02:19,070
+مرحلة الامبريو في كل مرحلة من المراحل بيكون
+
+30
+00:02:19,070 --> 00:02:23,330
+حواليها وسط غذائي في داخل جسم السيدة خاص فيها
+
+31
+00:02:23,330 --> 00:02:27,070
+يختلف عن الوسط اللي بيكون في الزيجوت أو يختلف عن
+
+32
+00:02:27,070 --> 00:02:30,630
+الوسط اللي بيكون في الامبريو فبالتالي لازم اوفر
+
+33
+00:02:30,630 --> 00:02:35,590
+وسط غذائي في المعمل يشبه الوسط الغذائي اللي بيكون
+
+34
+00:02:35,590 --> 00:02:38,650
+في الامبريو اللي بتكون فيها البويضة و اللي بيكون
+
+35
+00:02:38,650 --> 00:02:42,450
+فيها البويضة خلال انتقالها في ال fallopian tubeThe
+
+36
+00:02:42,450 --> 00:02:46,610
+culture media need to meet the metabolic need of
+
+37
+00:02:46,610 --> 00:02:52,450
+pre-implantation embryo by addressing genetic and
+
+38
+00:02:52,450 --> 00:02:55,830
+amino acid requirement in stage specific manner
+
+39
+00:02:55,830 --> 00:03:00,410
+بمعنى أخر أن مرحلة البويضة تحتاج إلى كمية من ال
+
+40
+00:03:00,410 --> 00:03:04,350
+amino acid تختلف عن المرحلة الجنينية تختلف عن
+
+41
+00:03:04,350 --> 00:03:08,750
+مرحلة الزيجوت فبالتالي لكل مرحلة احتياجاتها لازم
+
+42
+00:03:08,750 --> 00:03:11,330
+أعرف أنا هذه الاحتياجات وأوفرها في ال culture
+
+43
+00:03:11,330 --> 00:03:14,810
+mediaأول ما تم اكتشاف الـ Culture Media أو الـ
+
+44
+00:03:14,810 --> 00:03:20,850
+Media الخاصة بالـ IVF كان في عام 1980 في عام 1985
+
+45
+00:03:20,850 --> 00:03:25,170
+كان أول Media يصرح باستخدامها وكان يطلق عليها الـ
+
+46
+00:03:25,170 --> 00:03:32,390
+HITF بمعنى Human Tupule Fluid وهي تشبه إلى حد ال
+
+47
+00:03:32,390 --> 00:03:36,190
+Mediaإلى حد كبير جدا ال media الموجودة in vivo
+
+48
+00:03:36,190 --> 00:03:40,230
+environment to which the embryo is exposed يعني
+
+49
+00:03:40,230 --> 00:03:44,610
+تشبه بشكل كبير جدا ال media الداخلية التي يتعرض
+
+50
+00:03:44,610 --> 00:03:48,310
+إليها ال embryo خلال عملية انتقاله من ال fallopian
+
+51
+00:03:48,310 --> 00:03:52,870
+tube إلى الرحم الهدف الأساسي من ال culture media
+
+52
+00:03:52,870 --> 00:03:56,610
+أو ال embryo culture as a part of human assisted
+
+53
+00:03:56,610 --> 00:04:00,230
+reproduction is to provide a stable environment
+
+54
+00:04:00,230 --> 00:04:04,760
+for embryo to growand develop from fertilization
+
+55
+00:04:04,760 --> 00:04:10,160
+through the early stage for transfer into the
+
+56
+00:04:10,160 --> 00:04:14,020
+uterus or cryopreservation يعني بمعنى بسيط جدا
+
+57
+00:04:14,020 --> 00:04:17,520
+الهدف الأساسي من ال embryonic media أو ال embryo
+
+58
+00:04:17,520 --> 00:04:22,280
+media هي توفير ظروف مناخية تناسب الجنين في كل
+
+59
+00:04:22,280 --> 00:04:26,260
+مراحله في المراحل أثناء انتقاله من fallopian tube
+
+60
+00:04:26,720 --> 00:04:29,500
+في المراحل التي ينغرس فيها في بطانة الرحم في
+
+61
+00:04:29,500 --> 00:04:33,440
+المراحل التي تؤهله لعملية الـ Cryopreservation أي
+
+62
+00:04:33,440 --> 00:04:38,320
+التجميد باستخدام الـ Liquid Nitrogen فعلى سبيل
+
+63
+00:04:38,320 --> 00:04:42,900
+المثال، في ميديا تستخدم في الـ cleavage stage في
+
+64
+00:04:42,900 --> 00:04:46,360
+اليوم التاني والتالت شو يعني الـ cleavage stage؟
+
+65
+00:04:46,360 --> 00:04:51,360
+شو يعني اليوم التاني والتالت؟ ببساطة جدا، البويضة
+
+66
+00:04:51,360 --> 00:04:55,560
+بعد إخصابها بتمر بخمس أيام كل يوم بيصير فيها
+
+67
+00:04:55,560 --> 00:04:58,920
+انقسامانقسام اليوم الأول وانقسام اليوم التاني
+
+68
+00:04:58,920 --> 00:05:02,080
+وانقسام اليوم التالت وانقسام اليوم الرابع وانقسام
+
+69
+00:05:02,080 --> 00:05:06,500
+اليوم الخامس هذه كل يوم عبارة عن انقسام وفي كل يوم
+
+70
+00:05:06,500 --> 00:05:11,160
+تنتقل من مكان وفي كل يوم تنتقل من مكان إلى مكان
+
+71
+00:05:11,160 --> 00:05:16,620
+آخر خلال عملية الانتقال من Fallopian tube إلى
+
+72
+00:05:16,620 --> 00:05:22,020
+بيطانة الرحم ثم الانغراس فبالتالي احتياجته في
+
+73
+00:05:22,020 --> 00:05:25,520
+اليوم الأولللمادة الغذائية تختلف عن اليوم التاني،
+
+74
+00:05:25,520 --> 00:05:28,300
+تختلف عن التالت، تختلف عن الرابع، تختلف عن الخامس
+
+75
+00:05:28,300 --> 00:05:32,320
+و هكذا، فلازم كل يوم أعرف شو هو اليوم و شو هو
+
+76
+00:05:32,320 --> 00:05:35,560
+الاحتياجات فالcleavage stage for example دي اتنين
+
+77
+00:05:35,560 --> 00:05:41,240
+لديه تلاتة it has become clear that it isprefer to
+
+78
+00:05:41,240 --> 00:05:46,420
+transfer at the plastocyst stage day 5 or day 6
+
+79
+00:05:46,420 --> 00:05:50,160
+for the number of reasons شو يعني plastocyst؟ شو
+
+80
+00:05:50,160 --> 00:05:53,860
+يعني morella؟ هي عبارة عن مرحلة من مراحل تطور
+
+81
+00:05:53,860 --> 00:05:58,920
+الجنين، هناخدها باستفادة، سي goat, plastocyst,
+
+82
+00:05:59,840 --> 00:06:03,300
+morella، أسماء كتيرة هنتكلم عنها، بس احنا مش
+
+83
+00:06:03,300 --> 00:06:07,460
+هنستفيد في الحتة هذه، في اللحظة هذهفي عند عزبين
+
+84
+00:06:07,460 --> 00:06:12,100
+المثال spontaneous conception لـ human embryo does
+
+85
+00:06:12,100 --> 00:06:16,500
+not normally pass into the uterus until morella في
+
+86
+00:06:16,500 --> 00:06:20,220
+التلقيح الطبيعي وعملية التلقيح الطبيعية الـ
+
+87
+00:06:20,220 --> 00:06:26,320
+intercourses ال embryo ما بينتقل إلى الرحم إلا إذا
+
+88
+00:06:26,320 --> 00:06:29,900
+وصل لمرحلة الموريلا والموريلا هي عبارة عن خلية
+
+89
+00:06:29,900 --> 00:06:34,650
+تحتوي بداخلها على أكتر من 32 خليةهذا تعريف البسيط
+
+90
+00:06:34,650 --> 00:06:37,870
+خلّينا نعرفها بهذا الشكل حتى الآن و قدام هناخد
+
+91
+00:06:37,870 --> 00:06:41,970
+استفادة شوية عن موريلا to the early plastocyst
+
+92
+00:06:41,970 --> 00:06:46,830
+stage and the aortas is like not well occupied to
+
+93
+00:06:46,830 --> 00:06:50,830
+support the cleavage stage embryo يعني بيقول لي
+
+94
+00:06:50,830 --> 00:06:55,970
+ببساطة جدا أنه في الوضع الطبيعي و التلقيح الطبيعي
+
+95
+00:06:55,970 --> 00:07:02,510
+ال embryo لن ينتقل إلى الرحم إلا بعد أن تتحول
+
+96
+00:07:02,510 --> 00:07:08,160
+لموريلاوهي أحد أطوار الجنين إلى Plastocyst والـ
+
+97
+00:07:08,160 --> 00:07:13,980
+Plastocyst أكتر من 64 خلية ببساطة يعني إذا كان
+
+98
+00:07:13,980 --> 00:07:17,440
+موريلا معناه لسه مش هينزل إلى الرحم، هيظل في الـ
+
+99
+00:07:17,440 --> 00:07:21,580
+Fallopian tube وين انتقل لمرحلة Plastocyst؟ هينتقل
+
+100
+00:07:21,580 --> 00:07:26,980
+إلى الـ Uterus ويصيرله Implantationواخدوا بالك
+
+101
+00:07:26,980 --> 00:07:30,420
+طالما موريلا إلا إحتياجاتها طالما Plastocyst إلا
+
+102
+00:07:30,420 --> 00:07:34,420
+إحتياجات مختلفة الـ gonadotropin stimulation of
+
+103
+00:07:34,420 --> 00:07:38,400
+the ovary to provide an increased number of oocyte
+
+104
+00:07:38,400 --> 00:07:42,720
+result is very high circulating concentration of
+
+105
+00:07:42,720 --> 00:07:47,420
+estrogen that led to abnormal development and
+
+106
+00:07:47,420 --> 00:07:50,820
+functional activity of uterus خلال عملية تحفيز
+
+107
+00:07:50,820 --> 00:07:54,220
+المبيض الزوجة والسيدة بتاخد كمية كبيرة جدا من
+
+108
+00:07:54,220 --> 00:07:58,740
+الهرموناتهذه الهرمونات تعمل خربة خلّينا نسميها عدم
+
+109
+00:07:58,740 --> 00:08:04,780
+انتظام في الحالة العامة للسيدة في الدورة الدموية
+
+110
+00:08:04,780 --> 00:08:09,460
+للسيدة في عملية .. العمليات التي تحدث في ال
+
+111
+00:08:09,460 --> 00:08:12,960
+reproductive system نسبة إلى وجود كمية كبيرة جدا و
+
+112
+00:08:12,960 --> 00:08:16,180
+تركيز كبير وعالي من الاستروجين في الدورة الدموية
+
+113
+00:08:16,180 --> 00:08:19,800
+هذا ممكن يعمل abnormality في development of
+
+114
+00:08:19,800 --> 00:08:23,400
+unfunctional activity of uterus يعني بمعنى أخر
+
+115
+00:08:23,750 --> 00:08:28,110
+الرحم ما بيعمل بالطريقة المطلوبة في هذه اللحظة سبب
+
+116
+00:08:28,110 --> 00:08:32,550
+التالت بعض الأحيان بيقول ال culture to plastocyst
+
+117
+00:08:32,550 --> 00:08:38,550
+stage allowed for more extensive evaluation of the
+
+118
+00:08:38,550 --> 00:08:44,550
+embryo خاصة بال genetic testing أنا لما أجي أخلي
+
+119
+00:08:44,550 --> 00:08:48,250
+ال embryo في media ليوم أو يومين قبل عملية الإرجاع
+
+120
+00:08:48,250 --> 00:08:51,610
+هذا بتحلي فرصة أن أعمل selection شو يعني
+
+121
+00:08:51,610 --> 00:08:55,570
+selection؟أرجع على سبيل المثال الجنين السليم الذي
+
+122
+00:08:55,570 --> 00:08:59,430
+لا يحتوي على أمراض غيراثية أو أرجع الجنين الذكر أو
+
+123
+00:08:59,430 --> 00:09:03,370
+أرجع الجنين الأنثى يعني بتيح لفترة زمانية كافية أن
+
+124
+00:09:03,370 --> 00:09:08,210
+أعمل فحوصات جينية على الجنين قبل الإرجاع مما يضمن
+
+125
+00:09:08,210 --> 00:09:12,830
+ليه بشكل كبير إلى حد ما إرجاع الجنين المطلوب أو
+
+126
+00:09:12,830 --> 00:09:17,440
+الجنين السليمفي هندى من أشهر أنواع ال media اللى
+
+127
+00:09:17,440 --> 00:09:20,420
+استخدمت هي ال tissue culture media ال tissue
+
+128
+00:09:20,420 --> 00:09:24,000
+culture media من أشهر هذه ال media اللى استخدمت
+
+129
+00:09:24,000 --> 00:09:27,620
+وكانت تحتوي solution salt solution بيحتوى على
+
+130
+00:09:27,620 --> 00:09:29,480
+Sodium chloride, potassium chloride, calcium
+
+131
+00:09:29,480 --> 00:09:33,540
+chloride و low concentration of sodium bicarbonate
+
+132
+00:09:33,540 --> 00:09:37,860
+عشان تعمل ال balance في ال pH وهذه طبعا إلى حد ما
+
+133
+00:09:37,860 --> 00:09:43,720
+استخدمت بكمية كبيرة جدا for the study of the frog
+
+134
+00:09:43,720 --> 00:09:49,270
+heartنبضات قلب الضفدع و كانوا يستخدموها .. طبعا
+
+135
+00:09:49,270 --> 00:09:52,870
+كانوا زمان يستخلصوا و ينزعوا قلب الضفدع و يضيفوا
+
+136
+00:09:52,870 --> 00:09:56,030
+عليه ال ringer solution اللي هو عبارة عن Sodium
+
+137
+00:09:56,030 --> 00:09:58,350
+Chloride أو Potassium Chloride أو whatever و يشوف
+
+138
+00:09:58,350 --> 00:10:02,210
+هل هو باستجيب لهذه الأملح بقداش كمية استجابته فهم
+
+139
+00:10:02,210 --> 00:10:07,150
+بدوا يستخدموا هذه ال media إلى ال IVF أو لل IVF
+
+140
+00:10:07,150 --> 00:10:11,230
+بعدها أثبت كفاوب و لكن بعد كده تم تطوير الأمر بشكل
+
+141
+00:10:11,230 --> 00:10:14,930
+كبير جدا حاليا في عند media كاملة و media جاهزة
+
+142
+00:10:15,110 --> 00:10:18,650
+تستخدم بكفاءة عالية جدا إيش موجود في ال media؟
+
+143
+00:10:18,650 --> 00:10:21,270
+وإيش ال reagent اللي موجود؟ في عندي media بيسميها
+
+144
+00:10:21,270 --> 00:10:24,650
+cleavage media وفي media بيسميها plastocyst media
+
+145
+00:10:24,650 --> 00:10:28,510
+من اسمة cleavage media يعني media .. mediaة
+
+146
+00:10:28,510 --> 00:10:32,830
+الإنقسام الوسط الغذائي للإنقسام وهو يستخدم في
+
+147
+00:10:32,830 --> 00:10:36,870
+اليوم الأول والتاني والتالت من الحقن يعني لو أنا
+
+148
+00:10:36,870 --> 00:10:39,950
+حقنت ال boiler يوم السبت هستخدم ال cleavage media
+
+149
+00:10:39,950 --> 00:10:43,910
+يوم السبت والأحد والإتنينبلاستوست ميديا التلاتة
+
+150
+00:10:43,910 --> 00:10:47,470
+والاربعة ليش التلاتة والاربعة؟ أو ليش خمس أيام؟
+
+151
+00:10:47,470 --> 00:10:52,170
+لأن عملية الإرجع تحدث في اليوم التالت أو الرابع أو
+
+152
+00:10:52,170 --> 00:10:55,230
+الخامس في الدول المتقدمة في راجعه في الخامس فإن
+
+153
+00:10:55,230 --> 00:11:00,090
+بيراجعه في التالت أو الرابع كحد أقصى فيه طبعا في
+
+154
+00:11:00,090 --> 00:11:04,290
+ال media reagent منها اللي هي lorandaise serum
+
+155
+00:11:04,290 --> 00:11:08,490
+sperm preparation media هذه أنواع الميديا التي
+
+156
+00:11:08,490 --> 00:11:13,540
+تستخدم خلال الحقنفي عند الـ Hyaluronidase Media في
+
+157
+00:11:13,540 --> 00:11:15,960
+عند الـ Sperm Preparation Media وفي عند الـ PVP
+
+158
+00:11:15,960 --> 00:11:19,940
+Media يعني في أنا عندي أربع أنواع من ال media أو
+
+159
+00:11:19,940 --> 00:11:23,520
+أربع أنواع من ال reagent تستخدم بشكل كامل culture
+
+160
+00:11:23,520 --> 00:11:27,260
+media خاصة بالـ oocyte و ال embryo أفضل مثال عليها
+
+161
+00:11:27,260 --> 00:11:31,600
+ال cleavage media و ال blastocyst media cleavage
+
+162
+00:11:31,600 --> 00:11:33,780
+media في اليوم الأول و التالت و ال blastocyst في
+
+163
+00:11:33,780 --> 00:11:36,320
+اليوم الرابع و الخامس في ال media اسمها الـ
+
+164
+00:11:36,320 --> 00:11:39,160
+Hyaluronidase اللي استخدمناها في ال cumulus
+
+165
+00:11:39,160 --> 00:11:42,600
+removing ال strippingفي عند الـ sperm preparation
+
+166
+00:11:42,600 --> 00:11:46,120
+media وهذا هنستخدمها في الـ chapter اللي جاي علشان
+
+167
+00:11:46,120 --> 00:11:50,700
+أنا أحصل على single sperm صالح لل injection وفي
+
+168
+00:11:50,700 --> 00:11:55,060
+عند ال BVB media طبعا هذه ال BVB media هي عبارة عن
+
+169
+00:11:55,060 --> 00:11:59,120
+intracytoplasmic sperm injection media أو في بعض
+
+170
+00:11:59,120 --> 00:12:02,620
+الأحيان بيسموها media used during injection طبعا
+
+171
+00:12:02,620 --> 00:12:06,280
+مهمة جدا هذه ال media ووظيفتها إنها بتقلل قدرة ال
+
+172
+00:12:06,280 --> 00:12:09,220
+sperm على ال motility يعني بتعمل reduction in the
+
+173
+00:12:09,220 --> 00:12:13,030
+motility of spermatozoaتعمل prevent their sticking
+
+174
+00:12:13,030 --> 00:12:18,650
+to the injection pipet بمعنى آخر إن ال sperm قدرته
+
+175
+00:12:18,650 --> 00:12:21,350
+على الموتلتي بتقل يعني أنا بقدر أتحكم بال sperm و
+
+176
+00:12:21,350 --> 00:12:25,350
+أعمله catching أيضا تمنع اتصاق ال sperm بالجدار
+
+177
+00:12:25,350 --> 00:12:31,250
+الداخلي لل tube فبالتالي أنا ال sperm بقدر أشوف هو
+
+178
+00:12:31,250 --> 00:12:37,030
+بتحرك داخل ال tube خلال عملية الإنزال والسحبDuring
+
+179
+00:12:37,030 --> 00:12:40,610
+the procedure and to give more control over the
+
+180
+00:12:40,610 --> 00:12:44,970
+flow of a fluid in the XZ needle أيضًا بتعطيني
+
+181
+00:12:44,970 --> 00:12:49,010
+قدرة كبيرة جدًا على التحكم بالسائل أثناء دخوله
+
+182
+00:12:49,010 --> 00:12:52,710
+وخروجه من ال injection needle إبرة تلحقت عشان
+
+183
+00:12:52,710 --> 00:12:59,330
+كثافتها، الكثافة تبعتها كافية لإحداث تحكم واضح من
+
+184
+00:12:59,330 --> 00:13:02,170
+ال reagent اللي يستخدم إضافة إلى ال culture media
+
+185
+00:13:02,170 --> 00:13:06,020
+اللي هي الورينبيز وال C-Spermpreparation media و
+
+186
+00:13:06,020 --> 00:13:10,020
+ال PVP في ال oil طبعا انا بستخدم ال oil بشكل كبير
+
+187
+00:13:10,020 --> 00:13:14,560
+جدا عشان اغطي ال media لما انا بتردش اضيف قطرة
+
+188
+00:13:14,560 --> 00:13:17,320
+drop .. drop .. drop .. drop من ال media لازم
+
+189
+00:13:17,320 --> 00:13:22,000
+اغطيها ب oil هذا ال oil بيحمي ال media و بيحمي
+
+190
+00:13:22,000 --> 00:13:25,340
+البويضة اللي موجودة داخل ال media او بيحمي ال
+
+191
+00:13:25,340 --> 00:13:28,280
+embryo اللي موجود داخل ال media من ال external
+
+192
+00:13:28,280 --> 00:13:32,480
+environment factor فبيعطيها كمية حرارة ثابتة
+
+193
+00:13:32,480 --> 00:13:37,450
+cosmolarity ثابتةبـH ثابتة، humidity ثابتة مافي
+
+194
+00:13:37,450 --> 00:13:42,210
+fluctuation، تزحزح، تغير، عدم ثبات والـ oil
+
+195
+00:13:42,210 --> 00:13:46,830
+بيعمللي نوع من أنواع ال sterilization هائل جدا ده
+
+196
+00:13:46,830 --> 00:13:50,690
+ال quality of oil can be affected by shipping طبعا
+
+197
+00:13:50,690 --> 00:13:53,910
+أكيد بتأثر بال shipping، بال storage، ال light
+
+198
+00:13:53,910 --> 00:14:00,270
+فبالتالي لازم ال oil يتم شرائه من مكان موثوق فيه
+
+199
+00:14:00,270 --> 00:14:04,450
+خاص بال IPF مش أي oil يستخدمThe oil type commonly
+
+200
+00:14:04,450 --> 00:14:09,210
+used are mineral oil و paraffin oil و بعض الأحيان
+
+201
+00:14:09,210 --> 00:14:13,270
+الناس بتخلق mineral مقرفين يعني هذا أفضل ال oil
+
+202
+00:14:13,270 --> 00:14:17,010
+مستخدم ال human serum albumin يعتبر من المواد التي
+
+203
+00:14:17,010 --> 00:14:21,930
+تستخدم وتوجد في ال media بكمية معينة و بدرجة معينة
+
+204
+00:14:21,930 --> 00:14:25,570
+جدا السبب استخدامه لأنه بلعب على التوتر السطحي
+
+205
+00:14:25,570 --> 00:14:29,670
+بلعب على عامل التوتر السطحي كيف بيعمل و إيش وظيفته
+
+206
+00:14:30,020 --> 00:14:33,200
+بعمل preventing embryo and gamete from sticking
+
+207
+00:14:33,200 --> 00:14:41,440
+the inner surface of the tube يعني بمعنى آخر بعمل
+
+208
+00:14:41,440 --> 00:14:45,820
+منع لالتصاق ال embryo أو الجاميطات سواء كانت ال
+
+209
+00:14:45,820 --> 00:14:49,520
+oocyte أو ال sperm أن تلتصق بالجدار الداخلي خلال
+
+210
+00:14:49,520 --> 00:14:53,200
+عملية ال injection مش منطق أنا أجي أعمل injection
+
+211
+00:14:53,200 --> 00:14:55,860
+ولاجي ال sperm مملزج في الجدار الداخلي لل
+
+212
+00:14:55,860 --> 00:15:01,140
+injection needle مش راضي ينزل خطأأنا عملت pools
+
+213
+00:15:01,140 --> 00:15:05,920
+فاشل injection فاشل فلازم يكون فيه هندي human
+
+214
+00:15:05,920 --> 00:15:11,320
+serum albumin علشان يقلل ال sticking ال attachment
+
+215
+00:15:11,320 --> 00:15:14,620
+with the inner surface of injection needle
+
+216
+00:15:14,620 --> 00:15:19,020
+additionally albumin can protect embryo from toxic
+
+217
+00:15:19,020 --> 00:15:22,500
+substance in the culture environment and act as
+
+218
+00:15:22,500 --> 00:15:26,240
+buffer مهم جدا أن يحمل embryo من أي toxic material
+
+219
+00:15:26,240 --> 00:15:32,650
+وبيلعب ك bufferفي إمبريو بعد تطور الأحداث و تطور
+
+220
+00:15:32,650 --> 00:15:36,270
+الدراسات صار في عندي إمبريو جديد اسمه sequential
+
+221
+00:15:36,270 --> 00:15:40,810
+إمبريو يعني التدريجية أو التتابعية الـ early
+
+222
+00:15:40,810 --> 00:15:45,510
+culture media used in human IVF tend to be rather
+
+223
+00:15:45,510 --> 00:15:49,010
+simply very simple تحتوي على بعض السلط
+
+224
+00:15:49,010 --> 00:15:52,930
+والهيدروكربونيات والهيدروكربونيات يعني أول ما تم
+
+225
+00:15:52,930 --> 00:15:56,430
+إنشاء الميديا كانت بسيطة جدا water, sterile water,
+
+226
+00:15:56,550 --> 00:15:59,830
+sterile water, ultra pure waterفيها كمية من
+
+227
+00:15:59,830 --> 00:16:03,630
+الأملاح و فيها carbohydrate طيب بعد كده اتغير
+
+228
+00:16:03,630 --> 00:16:07,090
+الموضوع صاروا يضيفوا او يستخدموا ال media الخاصة
+
+229
+00:16:07,090 --> 00:16:11,630
+بال tissue culture و أعطت كفاءة كافية و كفاءة و
+
+230
+00:16:11,630 --> 00:16:17,670
+نتائج معينة بعد كده اتطور الموضوع فصار يدمجوا بعض
+
+231
+00:16:17,670 --> 00:16:20,970
+الأنواع المختلفة من ال media مع بعض البعض فصار في
+
+232
+00:16:20,970 --> 00:16:25,970
+عندي simple media those lead amino acid such as
+
+233
+00:16:25,970 --> 00:16:31,310
+those develop initial form mouseand adapted for
+
+234
+00:16:31,310 --> 00:16:34,930
+the human يعني أول أنواع ال simple media هي عبارة
+
+235
+00:16:34,930 --> 00:16:38,570
+عن ال simple media التي تفتقر إلى بعض أنواع من
+
+236
+00:16:38,570 --> 00:16:41,710
+الأحماض الأمنية كانوا يستخدموها في البداية علشان
+
+237
+00:16:41,710 --> 00:16:45,530
+ال ember الخاص بال mouse و يستخدموها مع ال human
+
+238
+00:16:45,530 --> 00:16:49,930
+أعطت نتاج أعطت نتاج مين مثال عليها؟ مثال عليها ال
+
+239
+00:16:49,930 --> 00:16:56,230
+human tubule fluid media ولكن we're not effective
+
+240
+00:16:56,570 --> 00:17:00,110
+in supporting a human embryo past itself صحيح أنها
+
+241
+00:17:00,110 --> 00:17:02,990
+أعطت نتائج في البدايات ولكن لما نيصل ال embryo إلى
+
+242
+00:17:02,990 --> 00:17:07,610
+8 خلايا مافي إلى أهمية مافي إلى أي قيمة فبالتالي
+
+243
+00:17:07,610 --> 00:17:12,150
+أثبتت فشلها مع ال embryo related with the human
+
+244
+00:17:12,150 --> 00:17:18,210
+عندما يصل إلى 8 خلايا فاستخدموا sequential median
+
+245
+00:17:18,210 --> 00:17:23,950
+بمعنى آخر في آخرعشر إلى خمس عشر سنة صار في عندي
+
+246
+00:17:23,950 --> 00:17:28,030
+shifting بشكل دراماتيكي في تطور ال media فأصبح
+
+247
+00:17:28,030 --> 00:17:33,790
+يستخدم media للcleavage و للplastocyst و لل embryo
+
+248
+00:17:33,790 --> 00:17:36,850
+يعني تلتة في واحد يعني هذه ال media تصلح لجميع
+
+249
+00:17:36,850 --> 00:17:42,030
+المراحل تطور الجنين so the stage of cleavage و
+
+250
+00:17:42,030 --> 00:17:44,850
+stage of embryo are cultured in one media
+
+251
+00:17:44,850 --> 00:17:49,320
+formation of the first one to three daysthen
+
+252
+00:17:49,320 --> 00:17:53,280
+subsequently placed into a second media formation
+
+253
+00:17:53,280 --> 00:17:56,320
+for the next two to three days to support Morella
+
+254
+00:17:56,320 --> 00:18:00,960
+and Plastocyst development يعني في .. في .. في ..
+
+255
+00:18:00,960 --> 00:18:05,380
+بمعنى آخر قبل ما يصير تطور للميديا و يصير dramatic
+
+256
+00:18:05,380 --> 00:18:09,040
+shifting بشكل واضح كانوا يستخدموا ميديا لأول تلت
+
+257
+00:18:09,040 --> 00:18:12,980
+أيام بعدين ينقلوا الجنين و يضيفوا ميديا تانية
+
+258
+00:18:12,980 --> 00:18:16,620
+لليوم الرابع والخامس ال media الأولى مسئولة عن ال
+
+259
+00:18:16,620 --> 00:18:21,810
+developmentوالميديا التانية مسؤولة عن تدعيم نمو
+
+260
+00:18:21,810 --> 00:18:27,190
+الموريلا والبلاستوسيست هذه الميديا قليلًا في
+
+261
+00:18:27,190 --> 00:18:30,990
+مجموعتهم تغيير مستوى الجليكوز ومجموعات الطاقة
+
+262
+00:18:30,990 --> 00:18:35,270
+الأخرى كذلك في تغيير المزيد من المزيد من المزيد من
+
+263
+00:18:35,270 --> 00:18:36,010
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+264
+00:18:36,010 --> 00:18:36,490
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+265
+00:18:36,490 --> 00:18:38,490
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+266
+00:18:38,490 --> 00:18:41,310
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+267
+00:18:41,310 --> 00:18:41,610
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+268
+00:18:41,610 --> 00:18:43,730
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+269
+00:18:43,730 --> 00:18:47,680
+المزيد من المزيد من المبالإضافة إلى كمية الـ
+
+270
+00:18:47,680 --> 00:18:51,820
+substrate اللي بتاعة الطاقة أضف إلى ذلك أنواع
+
+271
+00:18:51,820 --> 00:18:56,340
+الأحماض الأمينية هذا الاختلاف البسيط ما بينهم صورة
+
+272
+00:18:56,340 --> 00:19:01,020
+بتوضحلي شو يعني ال common integrity اللي موجودة في
+
+273
+00:19:01,020 --> 00:19:05,640
+ال sequential culture system في عند اليوم الأول و
+
+274
+00:19:05,640 --> 00:19:09,640
+اليوم التاني و اليوم التالتو اليوم الرابع و اليوم
+
+275
+00:19:09,640 --> 00:19:12,440
+الخامس و اليوم السادس هذه عبارة عن أيام الإنقسام
+
+276
+00:19:12,440 --> 00:19:16,560
+الستة في ناس بترجع في اليوم التالت أو بعد عفوًا
+
+277
+00:19:16,560 --> 00:19:21,580
+اليوم التالت و في ناس بترجع في اليوم الرابع أو
+
+278
+00:19:21,580 --> 00:19:28,160
+الخامس أو السادس بناءً على كفاءة الجنين وجودته الـ
+
+279
+00:19:28,160 --> 00:19:32,800
+sequential media هي عبارة عن media جزء منها أو هي
+
+280
+00:19:32,800 --> 00:19:36,930
+عبارة عن media تتكون من two partsالـ Part الأول أو
+
+281
+00:19:36,930 --> 00:19:40,770
+الـ Vial الأول يستخدم من اليوم الأول للتالت والـ
+
+282
+00:19:40,770 --> 00:19:44,670
+Vial التاني يستخدم من اليوم الرابع للخامس يحتوي
+
+283
+00:19:44,670 --> 00:19:48,710
+على نفس المواد ولكن بتركيز مختلفة هذا بنتسميه
+
+284
+00:19:48,710 --> 00:19:52,390
+Sequential Media التي تستخدم في اليوم الأول للتالت
+
+285
+00:19:52,390 --> 00:19:57,450
+تحتوي على كمية قليل جدا من الجريكوز فيها إيديتا
+
+286
+00:19:57,450 --> 00:20:00,290
+فيها بيروفيت فيها لاكتيت وما فيها essential amino
+
+287
+00:20:00,290 --> 00:20:04,500
+acidالتي تستخدم من اليوم الرابع للسادس فيها
+
+288
+00:20:04,500 --> 00:20:09,540
+essential amino acid فيها كمية واثيرة من الجليكوز
+
+289
+00:20:09,540 --> 00:20:13,960
+فيها بيروفيت و فيها لاكتيت أضف إلى ذلك no
+
+290
+00:20:13,960 --> 00:20:17,680
+essential amino acid no essential amino acid أو
+
+291
+00:20:17,680 --> 00:20:19,980
+fine non essential amino acid مش موجود عفوا فيها
+
+292
+00:20:19,980 --> 00:20:22,700
+non essential amino acid يعني بمعنى أخر non
+
+293
+00:20:22,700 --> 00:20:25,800
+essential amino acid موجود في البارت الأول موجود
+
+294
+00:20:25,800 --> 00:20:29,330
+في البارت التانيالجليكوز موجود في ال part الأول
+
+295
+00:20:29,330 --> 00:20:32,490
+بكمية قليلة في ال part التاني بكمية أعلى ال bio
+
+296
+00:20:32,490 --> 00:20:35,530
+rate موجود في كلاهما ال lactate موجود في كلاهما ال
+
+297
+00:20:35,530 --> 00:20:38,970
+Edita موجودة في ال part الأول مش موجودة في ال part
+
+298
+00:20:38,970 --> 00:20:42,190
+التاني و ال part التاني يختلف عن ال part الأول في
+
+299
+00:20:42,190 --> 00:20:45,250
+وجود ال essential amino acid في وجود ال essential
+
+300
+00:20:45,250 --> 00:20:48,630
+amino acid هذه بيسموها sequential cultural media
+
+301
+00:20:48,630 --> 00:20:51,470
+هي عبارة عن ميديا بتكوين من two files ال file
+
+302
+00:20:51,470 --> 00:20:54,320
+الأول لأول تلت أيام و الفعل التاني لتلت أياملتالي
+
+303
+00:20:54,320 --> 00:20:57,440
+تلت أيام و هو الرابع و الخمسة و السادس او الرابع و
+
+304
+00:20:57,440 --> 00:21:00,900
+الخمس و السادس استقدروا هذا الموضوع ب one media
+
+305
+00:21:00,900 --> 00:21:05,660
+وهي media يمكن ان تستخدم من اليوم الأول لليوم
+
+306
+00:21:05,660 --> 00:21:10,220
+السادس فيها non-essential فيها essential فيها
+
+307
+00:21:10,220 --> 00:21:13,820
+edita فيها jericose فيها pyruvate و فيها lactate
+
+308
+00:21:13,820 --> 00:21:18,280
+يعني كأنه بيقولك تحتوي على جميع المواد و اللي عاوز
+
+309
+00:21:18,280 --> 00:21:22,200
+الجنين ياخدهاللي عاوزة الموريلا من المواد تاخدها
+
+310
+00:21:22,200 --> 00:21:26,860
+عاوزة بلاستوست مواد معينة تاخدها الزيجوت عاوزة من
+
+311
+00:21:26,860 --> 00:21:30,500
+المواد معينة تاخدها والمواد التانية مايلها side
+
+312
+00:21:30,500 --> 00:21:35,460
+effect عليها أشهر المواد الموجودة الجليكوز الذي
+
+313
+00:21:35,460 --> 00:21:40,120
+يعتبر أشهر وأكبر مادة موجودة في ال culture media
+
+314
+00:21:40,120 --> 00:21:46,070
+الجنين بيحتاجهand is one of the primary variable
+
+315
+00:21:46,070 --> 00:21:49,310
+in sequential media culture media أكيد لأنه قولنا
+
+316
+00:21:49,310 --> 00:21:53,890
+الفي ال very low في step one أو ال vial one و very
+
+317
+00:21:53,890 --> 00:21:57,010
+high في ال vial two طبعا ال cleavage stage human
+
+318
+00:21:57,010 --> 00:22:03,050
+embryo can be used glucose ولكن بكميات قليلة بيزيد
+
+319
+00:22:03,050 --> 00:22:07,170
+كل ما زاد عمر الجنين ال lactate و ال pyruvate the
+
+320
+00:22:07,170 --> 00:22:11,480
+additionof lactate to early salt solution media
+
+321
+00:22:11,480 --> 00:22:16,320
+was instrumental in supporting development from
+
+322
+00:22:16,320 --> 00:22:19,380
+the two cell stage of the mouse embryo وجدوا إن
+
+323
+00:22:19,380 --> 00:22:25,060
+اللاكتات يستخدم بشكل كبير جدا في تدعيم نمو الخلايا
+
+324
+00:22:25,060 --> 00:22:29,260
+أو البويضة الملقحة لما تصل إلى ال two stage خصوصا
+
+325
+00:22:29,260 --> 00:22:34,200
+ال embryo mouse أو ال mouse of embryo البيروفيت تم
+
+326
+00:22:34,200 --> 00:22:39,290
+فيما بعد اكتشافه واستخدامهأعطى نتائج فعالة في
+
+327
+00:22:39,290 --> 00:22:45,690
+تطوير وتحسين نضوج الزيجون وتم استخدامه as a
+
+328
+00:22:45,690 --> 00:22:48,970
+primary source of energy for a cleavage stage
+
+329
+00:22:48,970 --> 00:22:52,570
+embryo including a human where it is used
+
+330
+00:22:52,570 --> 00:22:56,210
+throughout development of a blastocyst stageيعني
+
+331
+00:22:56,210 --> 00:22:59,310
+بمعنى أخر البيوروفيت أصبح استخدامه أكثر من
+
+332
+00:22:59,310 --> 00:23:04,250
+اللاكتات as source of energy سواء كان في المرحلة
+
+333
+00:23:04,250 --> 00:23:07,470
+المتقدمة أول تلات أيام أو في مرحلة الـPlesiocyst
+
+334
+00:23:07,470 --> 00:23:12,190
+اللي بتظهر في اليوم الرابع أو الخامس أو السادس بعض
+
+335
+00:23:12,190 --> 00:23:16,590
+الأحماض الأمنية التي تلعب دور أساسي كمصدر من مصادر
+
+336
+00:23:16,590 --> 00:23:20,970
+الطاقة المستخدمة من قبل الجنين أثناء عملية ال
+
+337
+00:23:20,970 --> 00:23:24,540
+developmentولكن أيضًا تساعد في التدخل في
+
+338
+00:23:24,540 --> 00:23:27,780
+الهيموستاسي داخل الخلايا رغم أنها تعتبر مصدر
+
+339
+00:23:27,780 --> 00:23:33,040
+للطاقة أن الـ Amino Acid أصبحت تستخدم كمصدر مهم
+
+340
+00:23:33,040 --> 00:23:36,320
+جدًا للمحافظة على الهيموستاسي داخل الخلايا فهي
+
+341
+00:23:36,320 --> 00:23:40,900
+تعمل كـ Buffering أيضًا تعمل كـ Antioxidant وتعمل
+
+342
+00:23:40,900 --> 00:23:45,280
+أيضًا Organic Osmolites to control cell volume
+
+343
+00:23:45,280 --> 00:23:49,980
+يعني الـ Amino Acid مادة مش هينة في الـ Culture
+
+344
+00:23:49,980 --> 00:23:55,090
+Media خاصةفي بعد اليوم التالت Amino acid,
+
+345
+00:23:55,290 --> 00:23:58,950
+pyruvate, lactate were recognized as preferred
+
+346
+00:23:58,950 --> 00:24:03,850
+energy source for all or for the early embryo over
+
+347
+00:24:03,850 --> 00:24:08,050
+glucose يعني لو أنا قرنت ال substance كلهم مع ال
+
+348
+00:24:08,050 --> 00:24:12,590
+glucose بلاقي إنه أكثر استخدام لمصادر الطاقة لل
+
+349
+00:24:12,590 --> 00:24:17,070
+embryo وخاصة في المناطق المبكرة يعني أول يومين تلت
+
+350
+00:24:17,070 --> 00:24:21,530
+أيام يستخدم ال amino acid كمصدر للطاقةبيروفيت والـ
+
+351
+00:24:21,530 --> 00:24:27,630
+Lactate يعتبر مفضل أو مفضلين عن الجليكوز بالنسبة
+
+352
+00:24:27,630 --> 00:24:32,850
+للجنين في أول أيامه في أول أيام طبعا بعض الدراسات
+
+353
+00:24:32,850 --> 00:24:37,930
+التي حدثت على ال mouse embryo Demonstrated وجدت إن
+
+354
+00:24:37,930 --> 00:24:41,030
+non-essential amino acids are important during
+
+355
+00:24:41,030 --> 00:24:42,610
+early embryo development
+
+356
+00:24:46,110 --> 00:24:48,410
+Essentially and non-essential amino acids should
+
+357
+00:24:48,410 --> 00:24:52,450
+be included in the media after 8th to 6th cell
+
+358
+00:24:52,450 --> 00:24:56,450
+stage ايش يعني 6th stage؟ خدوا بالكوا اليوم الأول
+
+359
+00:24:56,450 --> 00:25:05,190
+انقسم بقدر 2 cell التاني 4 التالت 8 الرابع 16
+
+360
+00:25:05,190 --> 00:25:12,470
+الخامس 32 السادس 64 لأن الأمر متضائف هي المقصود من
+
+361
+00:25:12,470 --> 00:25:17,360
+انقسم إذا ال 8 خلايا بيكون في اليومالثالث لأنه
+
+362
+00:25:17,360 --> 00:25:21,020
+عندى أربعة تمانية هذه الفكرة الموجودة فبقول لي
+
+363
+00:25:21,020 --> 00:25:25,080
+ببساطة جدا أنه بناء على التجربة وجدوا أن الأحماض
+
+364
+00:25:25,080 --> 00:25:29,220
+الأمينية الغير أساسية تعتبر مهمة لتطور الجنين في
+
+365
+00:25:29,220 --> 00:25:32,660
+مراحل الأولى بينما الأساسية والغير أساسية من حيث
+
+366
+00:25:32,660 --> 00:25:37,640
+الأحماض الأمينية تعتبر لتطور ونضوج ونمو الجنين في
+
+367
+00:25:37,640 --> 00:25:42,760
+المراحل بعد اليوم التالت لما يصل لست اتمن خلايا أو
+
+368
+00:25:42,760 --> 00:25:47,720
+ستاشر خلية يعني في اليوم التالتواليوم الرابع The
+
+369
+00:25:47,720 --> 00:25:52,780
+use of amino acid and specifically glutamine in
+
+370
+00:25:52,780 --> 00:25:55,700
+the media is associated with ammonium accumulation
+
+371
+00:25:55,700 --> 00:25:59,660
+هل في accumulation للأمونيا بتصير داخل ال media أو
+
+372
+00:25:59,660 --> 00:26:03,380
+بتصير داخل الأكيد في accumulation لأنه خلية
+
+373
+00:26:03,380 --> 00:26:08,600
+والخلية بيطلع منها waste product واجدوا على سبيل
+
+374
+00:26:08,600 --> 00:26:13,360
+المثال إن embryo واحد في اليوم الرابع يستطيع إنتاج
+
+375
+00:26:13,360 --> 00:26:17,500
+100 micro mole من الأمونيا and the amino acid
+
+376
+00:26:17,500 --> 00:26:21,220
+breakdown added few charge .. few ذرع to this
+
+377
+00:26:21,220 --> 00:26:24,620
+which can affected in the development capacity and
+
+378
+00:26:24,620 --> 00:26:27,740
+gene expression يعني تصور أنا عندي embryo في اليوم
+
+379
+00:26:27,740 --> 00:26:35,040
+الرابع يعني عدد خليات2، 4، 8، 16 خلية يستطيع إنتاج
+
+380
+00:26:35,040 --> 00:26:38,760
+100 micromole من الأمونيا بالإضافة إلى وجود
+
+381
+00:26:38,760 --> 00:26:43,560
+الأحماض الأمنية التي تتكسر داخل الوسط أو داخل ال
+
+382
+00:26:43,560 --> 00:26:47,280
+media هيزيد مستوى الأمونيا زيادة مستوى الأمونيا
+
+383
+00:26:47,280 --> 00:26:51,460
+بيعمل feedback أو negative feedback على ال
+
+384
+00:26:51,460 --> 00:26:55,000
+capacity لل gene development لل embryo development
+
+385
+00:26:55,000 --> 00:26:58,520
+و ال gene expression يعني في تأثير سلبي على ال
+
+386
+00:26:58,520 --> 00:27:02,960
+gene expression لل embryoوالـ capacity التي تتعلق
+
+387
+00:27:02,960 --> 00:27:07,020
+بالـ embryo development فبالتالي لازم نتخلص منها
+
+388
+00:27:07,020 --> 00:27:12,220
+من خلال وجود system معين في الـ osmolarity an
+
+389
+00:27:12,220 --> 00:27:18,340
+important concept to be aware of in regard to
+
+390
+00:27:18,340 --> 00:27:22,560
+culture media is osmolarity and it is resulting
+
+391
+00:27:22,560 --> 00:27:26,820
+affected one cell on the cell volume and embryo
+
+392
+00:27:26,820 --> 00:27:30,680
+development ال osmolarity لو اختلفتال volume الخاص
+
+393
+00:27:30,680 --> 00:27:34,420
+بال embryo هيختلف ال development الخاص بال embryo
+
+394
+00:27:34,420 --> 00:27:38,820
+هتختلف فعلى سبيل المثال بناء على التجارب وجدوا ان
+
+395
+00:27:38,820 --> 00:27:42,500
+ال high osmolarity كان affected embryo development
+
+396
+00:27:42,500 --> 00:27:46,980
+and was one of the underlying causes of the two
+
+397
+00:27:46,980 --> 00:27:50,380
+cell blocking observed in early embryo culture
+
+398
+00:27:50,380 --> 00:27:54,060
+media study شو يعني معنى الكلام؟ وجدوا ان ارتفاع
+
+399
+00:27:54,060 --> 00:27:58,290
+ال osmolarity في ال media خلالتحضين الجنين في هذه
+
+400
+00:27:58,290 --> 00:28:01,830
+الـ media في اليوم التالت أو اليوم الرابع يؤدي إلى
+
+401
+00:28:01,830 --> 00:28:06,410
+إيقاف أو اليوم التاني ممكن يؤدي إلى إيقاف تطول
+
+402
+00:28:06,410 --> 00:28:10,510
+الجنين في الاتنين cell يعني ينقسم في انقسام الأول
+
+403
+00:28:10,510 --> 00:28:14,650
+وانقسام التاني بس يعني بيقف فقط أن خلية فيها
+
+404
+00:28:14,650 --> 00:28:18,190
+خليتين خلية كبيرة بداخل ال two cell يعني تقريبا
+
+405
+00:28:18,190 --> 00:28:22,150
+يقف في نهاية اليوم الأول و بداية اليوم التاني ماهو
+
+406
+00:28:22,150 --> 00:28:26,670
+هذا اللي يجعله يجف انقسام الخلايا؟blocking a two
+
+407
+00:28:26,670 --> 00:28:32,830
+-cell هو وجود نسبة ومستوى عالي من الـosmolarity so
+
+408
+00:28:32,830 --> 00:28:35,970
+high osmolarity will be affected on the
+
+409
+00:28:35,970 --> 00:28:39,410
+development of embryo and it is considered as the
+
+410
+00:28:39,410 --> 00:28:45,030
+one causes of two-cell block بعض الدراسات اللي
+
+411
+00:28:45,030 --> 00:28:49,010
+أجريت على أحماض أمينية مختلفة وجدت إن provided
+
+412
+00:28:49,010 --> 00:28:52,670
+prediction against high osmolarity and are those
+
+413
+00:28:52,670 --> 00:28:57,280
+recommended in all mediaدراسات حدثت على بعض
+
+414
+00:28:57,280 --> 00:28:59,920
+اللحماض الأمنية وجدت إن هذه اللحماض الأمنية بتلعب
+
+415
+00:28:59,920 --> 00:29:03,360
+دور إيجابي في حماية ال embryo من ال isoglarity
+
+416
+00:29:03,360 --> 00:29:07,240
+فبالتالي بتمنع من ال two cell block بعض ال
+
+417
+00:29:07,240 --> 00:29:11,460
+additive زي ال antioxidant يمكن أن تضاف إلى ال
+
+418
+00:29:11,460 --> 00:29:14,220
+media ومن أشهر هذه ال antioxidant ال pyruvate it
+
+419
+00:29:14,220 --> 00:29:18,620
+will be pyruvate act as powerful antioxidant
+
+420
+00:29:18,620 --> 00:29:22,680
+فبالتالي بيحمي ال embryo من التأثير السلبي والسيء
+
+421
+00:29:22,680 --> 00:29:28,160
+لل reactive oxygen speciesمن أشهر أنواع الـ
+
+422
+00:29:28,160 --> 00:29:33,280
+Antioxidant إيثايل بيروفيت وميثايل بيروفيت وأيضا
+
+423
+00:29:33,280 --> 00:29:37,200
+في عيني الـ Sodium Pyruvate بيعتبر من أشهر أنواع
+
+424
+00:29:37,200 --> 00:29:43,540
+الـ Antioxidant التي قد تستخدم في حماية الـ embryo
+
+425
+00:29:43,540 --> 00:29:50,630
+من الـ oxidative stressوتعمل بشكل كبير جدا على
+
+426
+00:29:50,630 --> 00:29:53,790
+تدعيم الـ embryo الخاص بالماوس خلال عملية الـ
+
+427
+00:29:53,790 --> 00:29:59,170
+development عالية مصدر من مصادر الطاقة مصدر من
+
+428
+00:29:59,170 --> 00:30:03,030
+مصادر الطاقة فبالتالي الـ Pyruvate مهم جدا في
+
+429
+00:30:03,030 --> 00:30:07,710
+إحداث stability بنسبة و بكمية و بمستوى عالي جدا
+
+430
+00:30:07,710 --> 00:30:13,850
+كمان بعمل increasing لـ membrane permeability
+
+431
+00:30:13,850 --> 00:30:19,190
+factor which could have an impact on bothImbrio or
+
+432
+00:30:19,190 --> 00:30:24,110
+imbrio metabolism or ability to scavenge الرُس
+
+433
+00:30:24,110 --> 00:30:29,950
+يعني مقاومة الرُس التغلب على الرُس الرُس اختصار لل
+
+434
+00:30:29,950 --> 00:30:35,430
+reactive oxygen species وهي very toxic substance
+
+435
+00:30:35,430 --> 00:30:42,050
+harmful harmful harmful سؤال بطرح نفسه هل الجليكوز
+
+436
+00:30:42,050 --> 00:30:47,930
+يعتبر مادة أساسية او مادة مضرة؟الجليكوز تُعتبر
+
+437
+00:30:47,930 --> 00:30:53,090
+essential أو harmful substance The toxicity of
+
+438
+00:30:53,090 --> 00:30:57,210
+glicose for the early embryo is controversial
+
+439
+00:30:57,210 --> 00:31:01,930
+بمعنى آخر اختلف العلماء حول تأثير الجليكوز على
+
+440
+00:31:01,930 --> 00:31:05,430
+تطور الجنين في مراحل الأولية بعضهم قال بيأثر
+
+441
+00:31:05,430 --> 00:31:08,650
+التأثير السلبي بعضهم قال يعني toxic و بعضهم قال لأ
+
+442
+00:31:08,650 --> 00:31:11,950
+ما إلو أي علاقة أو ما إلو تأثير Provoist study
+
+443
+00:31:11,950 --> 00:31:15,870
+conclude that glicose is not harmful for the early
+
+444
+00:31:15,870 --> 00:31:22,040
+embryoفي المقابل في دراسات تانية قالت إن الجليكوز
+
+445
+00:31:22,040 --> 00:31:27,640
+والفركتوز يعتبروا من المكونات or fractose is
+
+446
+00:31:27,640 --> 00:31:31,080
+essential and amino acid were considered a key of
+
+447
+00:31:31,080 --> 00:31:34,140
+overcoming two cell blocking possible by
+
+448
+00:31:34,140 --> 00:31:38,280
+regulating the reactive oxygen species يعني بمعنى
+
+449
+00:31:38,280 --> 00:31:44,760
+أخر دراسة أخرى قالت وحدثت أن الجليكوز والفركتوز
+
+450
+00:31:44,760 --> 00:31:48,710
+essentialوmylo acid بلعب دور كبير جدا في حماية ال
+
+451
+00:31:48,710 --> 00:31:53,050
+embryo من الروس ويمنع حدوث ال two cell blocking
+
+452
+00:31:53,050 --> 00:31:57,810
+study showed that the reduction in the embryo
+
+453
+00:31:57,810 --> 00:32:00,010
+quality was associated with the high level of
+
+454
+00:32:00,010 --> 00:32:04,930
+glucose أي دراسة تانية in another site or in
+
+455
+00:32:04,930 --> 00:32:08,570
+another hand another study found that a media
+
+456
+00:32:08,570 --> 00:32:12,980
+content 4.7 millimole per literChelicose
+
+457
+00:32:12,980 --> 00:32:15,580
+supporting the human embryo development to
+
+458
+00:32:15,580 --> 00:32:20,180
+plasticest with high effectiveness يعني حتى
+
+459
+00:32:20,180 --> 00:32:25,880
+الدراسات مختلفة علشان كده أنا مابقدر أحكم على مادة
+
+460
+00:32:25,880 --> 00:32:29,840
+إلا بعد أدرسها على المجتمع اللي أنا بعيش فيه لأنه
+
+461
+00:32:29,840 --> 00:32:35,160
+من مجتمع لمجتمع من عدد لعدد تختلف نتائج الدراسة
+
+462
+00:32:35,160 --> 00:32:39,160
+study compared three cultures فيه study عملت
+
+463
+00:32:39,160 --> 00:32:43,350
+comparingلتأثير تلت أنواع من الـ Media الـ Media
+
+464
+00:32:43,350 --> 00:32:47,090
+الأولى P1 بتحتوى على جليكوز Free مافيش فيها جليكوز
+
+465
+00:32:47,090 --> 00:32:52,750
+يعني و Media اسمها SIM1 بتحتوى على 1 ميلي مول من
+
+466
+00:32:52,750 --> 00:32:57,650
+الجليكوز و Media اسمها Universal IVF Media بتحتوى
+
+467
+00:32:57,650 --> 00:33:02,230
+على 5.55 ميلي مول Bare Little للجليكوز يعني Media
+
+468
+00:33:02,230 --> 00:33:05,090
+مافيش فيهاو ميديا فيها كمية قليلة و ميديا فيها
+
+469
+00:33:05,090 --> 00:33:08,790
+كمية كبيرة جدا طب النتائج ببساطة جدا demonstrate
+
+470
+00:33:08,790 --> 00:33:12,490
+that high concentration did not affected in the
+
+471
+00:33:12,490 --> 00:33:17,390
+embryo quality but result in high polyploidy
+
+472
+00:33:17,390 --> 00:33:24,790
+fertilized and affected cleavage rate while SIMI
+
+473
+00:33:24,790 --> 00:33:27,750
+had beneficial effect on the embryo development
+
+474
+00:33:28,360 --> 00:33:32,500
+يعني بمعنى آخر الدراسة استخلصت إن وجود الجليكوز
+
+475
+00:33:32,500 --> 00:33:36,140
+بكميات كبيرة جدا ما بتأثر على جودة الـ Imperium
+
+476
+00:33:36,140 --> 00:33:41,980
+كجودة ولكن ممكن تؤدي إلى وجود polyploidy
+
+477
+00:33:41,980 --> 00:33:46,180
+fertilization ممكن تؤثر على الـ cleavage rate لل
+
+478
+00:33:46,180 --> 00:33:51,160
+Imperium بينما النوع التاني الـ media رقم 2 اللي
+
+479
+00:33:51,160 --> 00:33:57,380
+فيها كمية قليلة وجد إن هيله تأثير إيجابي علىنمو
+
+480
+00:33:57,380 --> 00:34:02,500
+وتطور الجنين it has been suggested that glucose is
+
+481
+00:34:02,500 --> 00:34:07,700
+not inhibitor or have negative effect for the
+
+482
+00:34:07,700 --> 00:34:11,380
+early embryo and the concentration that mimics the
+
+483
+00:34:11,380 --> 00:34:15,180
+in vivo condition of voiding extremely خلاصة هذه
+
+484
+00:34:15,180 --> 00:34:19,960
+الدراسة قالت أن الجليكوز لا يؤثر تأثير سلبي على
+
+485
+00:34:19,960 --> 00:34:26,150
+تطور الجنين ونموه طالمايحاكي نسبته نسبة طبيعية
+
+486
+00:34:26,150 --> 00:34:30,090
+الموجودة في جسم السيدة أو في جسم الأنثى ما لم يزيد
+
+487
+00:34:30,090 --> 00:34:34,510
+ما لم يزيد زيادته ساعتها بيأثر مش على ال quality
+
+488
+00:34:34,510 --> 00:34:40,830
+بيأثر على ال polyploidy بيأثر على ال polyploidy
+
+489
+00:34:40,830 --> 00:34:43,870
+بيأثر على ال polyploidy fertilization وبيأثر على
+
+490
+00:34:43,870 --> 00:34:47,730
+ال cleavage rate بيأثر على ال cleavage rate بهذا
+
+491
+00:34:47,730 --> 00:34:52,550
+الشكل نكون قد أنهينا من ال chapterهذا الشبتر
+
+492
+00:34:52,550 --> 00:34:56,110
+الشبتر الرابع على أمل أن نلتقي في شبتر جديد الشبتر
+
+493
+00:34:56,110 --> 00:34:59,970
+الجديد سوف نتحدث فيه عن كيف تتم عملية الحقن
+
+494
+00:34:59,970 --> 00:35:06,710
+process على أمل أن نلتقي دائما على خير دمتم في حفظ
+
+495
+00:35:06,710 --> 00:35:06,910
+الله
+
diff --git a/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/xq8dGPuJD2c_postprocess.srt b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/xq8dGPuJD2c_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..6db60c91faf9ae4032af3e7c277cd176fb3759bd
--- /dev/null
+++ b/PL9fwy3NUQKwZ2maYQWAufx8JKyPTiiP30/xq8dGPuJD2c_postprocess.srt
@@ -0,0 +1,3056 @@
+1
+00:00:01,300 --> 00:00:05,440
+بسم الله الرحمن الرحيم والصلاة والسلام على أشرف
+
+2
+00:00:05,440 --> 00:00:10,820
+المرسلين سيدنا محمد وعلى آله وصحبه أجمعين طلابنا
+
+3
+00:00:10,820 --> 00:00:15,120
+الأعزاء نرجو من الله الكريم أن تكونوا جميعا بخير
+
+4
+00:00:15,120 --> 00:00:21,520
+اليوم سوف نستكمل ما بدأنا فيه من الجزء السادس من
+
+5
+00:00:21,520 --> 00:00:26,380
+محاضرة التي كانت تتحدث عن عملية ال implantation
+
+6
+00:00:26,380 --> 00:00:31,530
+الخاصة بال embryo بعد نجاح عملية الحقن المجهريوكيف
+
+7
+00:00:31,530 --> 00:00:36,530
+يمكن أن ينتقل الجنين من مكان التلقيح المتمثل في
+
+8
+00:00:36,530 --> 00:00:41,090
+الثلث الأول من قناة fallopian tube وصولا إلى الرحم
+
+9
+00:00:41,090 --> 00:00:47,350
+ثم بعد ذلك الانطلاق في مرحلة انغراس وتكوين المشيمة
+
+10
+00:00:47,350 --> 00:00:51,490
+ثم تحدثنا عن مصطلح جديد وهو عبارة عن ال biopsy
+
+11
+00:00:51,490 --> 00:00:56,470
+الذي يستخدم لتشخيص بعض الأمراض الوراثية التي تنتقل
+
+12
+00:00:56,470 --> 00:01:01,190
+من الأم إلى الأبناء أوبعض الأمراض الوراثية التي
+
+13
+00:01:01,190 --> 00:01:06,730
+لها علاقة بالعائلة ككل ثم سوف ننتقل إلى أنواع أخرى
+
+14
+00:01:06,730 --> 00:01:11,530
+من ال biopsy ولكن في البداية تحدثنا عن نوع واحد من
+
+15
+00:01:11,530 --> 00:01:16,290
+ال biopsy وهي عبارة عن ال polar body biopsy سننتقل
+
+16
+00:01:16,290 --> 00:01:21,550
+للحديث عن ال embryo biopsy و الحديث عن ال PGD و ال
+
+17
+00:01:21,550 --> 00:01:27,790
+sex selection أيضا لأن كلا الموضوعينلهم علاقة
+
+18
+00:01:27,790 --> 00:01:34,470
+كبيرة جدا بعملية الـ embryo biopsy خاصة لعمليات
+
+19
+00:01:34,470 --> 00:01:38,110
+الحقن المجهري وبعض العائلات التي تعاني من أمراض
+
+20
+00:01:38,110 --> 00:01:42,450
+وراثية معينة أو التي تحتاج إلى عمل تحديد جنس
+
+21
+00:01:42,450 --> 00:01:45,510
+للمولود سواء كان يحتاجوا إلى مولود بكر أو مولود
+
+22
+00:01:45,510 --> 00:01:49,650
+أنثى هذا ما سوف نتحدث عنه في محاضرة اليوم إن شاء
+
+23
+00:01:49,650 --> 00:01:54,970
+الله المتعلقة بالجزء السادس أو الشبط الرقم 6 الجزء
+
+24
+00:01:54,970 --> 00:01:59,970
+2لما تحدثنا عن ال polar body تحدثنا إن أنا عندي ال
+
+25
+00:01:59,970 --> 00:02:03,030
+two polar body فممكن أخد ال first polar body وممكن
+
+26
+00:02:03,030 --> 00:02:05,890
+أخد ال second polar body أو ممكن أخد ال two polar
+
+27
+00:02:05,890 --> 00:02:10,410
+body مع بعضهم البعض ومن أشهر أنواع الفحوصات التي
+
+28
+00:02:10,410 --> 00:02:14,370
+يمكن أن تجرى على ال polar body تحت مصطلح polar
+
+29
+00:02:14,370 --> 00:02:17,610
+body biopsy إما فحص ال fish technique وهو ال
+
+30
+00:02:17,610 --> 00:02:21,350
+fluorescent in situ hybridization أو فحص ال PCR
+
+31
+00:02:21,350 --> 00:02:27,000
+وال PCR بشكل أساسي عملية يتم فيها مضاعفةالـ DNA أو
+
+32
+00:02:27,000 --> 00:02:30,660
+ضعفة fragment من الـ DNA إذا أنا ببحث عن جين معين
+
+33
+00:02:30,660 --> 00:02:33,960
+أو defect في جين معين أما ال fluorescent in situ
+
+34
+00:02:33,960 --> 00:02:38,120
+hybridization أنا بدي أعمل targeting ل part معين ل
+
+35
+00:02:38,120 --> 00:02:41,540
+sequence معينة أو لجين معين إذا كنت بدور على
+
+36
+00:02:41,540 --> 00:02:45,760
+defect gene بشكل الكامل هذا المقصود بال
+
+37
+00:02:45,760 --> 00:02:48,900
+fluorescent in situ hybridization و ال PCR أو
+
+38
+00:02:48,900 --> 00:02:54,840
+polymerase chain reactionطبعاً ال transfer عملية
+
+39
+00:02:54,840 --> 00:02:59,320
+ال transfer ل ال embryo عملية تعتبر very critical
+
+40
+00:02:59,320 --> 00:03:04,000
+.. very critical و عملية ال transfer ل ال .. أو ال
+
+41
+00:03:04,000 --> 00:03:07,440
+biopsy خلينا نسميها من منطلق آخر ل ال embryo
+
+42
+00:03:07,440 --> 00:03:12,020
+biopsy أو .. أو polar polar biopsy تعتبر عملية
+
+43
+00:03:12,020 --> 00:03:16,340
+very critical أي خطأ فيها يودي إلى تدمير الجنين
+
+44
+00:03:16,340 --> 00:03:20,550
+بشكل كامل فبالتالي أنا بفقدجنين رغم أنه عملية
+
+45
+00:03:20,550 --> 00:03:24,370
+الحقن أي ال fertilization عملية طبيعية و عملية
+
+46
+00:03:24,370 --> 00:03:27,850
+ناجحة transfer for fluorescent in situ
+
+47
+00:03:27,850 --> 00:03:31,910
+hybridization تختلف اختلافا كليا عن العملية اللي
+
+48
+00:03:31,910 --> 00:03:34,910
+انا بدي استخدم فيها ال PCR يعني لو انا اليوم بدي
+
+49
+00:03:34,910 --> 00:03:40,000
+اعمل fish techniqueعملية نقل الـ polar body تختلف
+
+50
+00:03:40,000 --> 00:03:42,900
+عن عملية نقلها إذا أنا بدي أعمل ال PCR فبالتالي في
+
+51
+00:03:42,900 --> 00:03:46,440
+حالة ال fish technique immediately after biopsy of
+
+52
+00:03:46,440 --> 00:03:49,940
+an oocyte the corresponding polar body are placed
+
+53
+00:03:49,940 --> 00:03:54,080
+in the naporing droplet of the media until the
+
+54
+00:03:54,080 --> 00:03:59,960
+oocyte are biopsied بمعنى إنه أنا مباشرة أنا عشرين
+
+55
+00:03:59,960 --> 00:04:03,140
+بوايدة لعشرين بوايدة بسحب منهم ال polar body و ال
+
+56
+00:04:03,140 --> 00:04:07,840
+polar body بنقلهم إلىقطرة مجاورة للقطرة التي تحتوي
+
+57
+00:04:07,840 --> 00:04:11,140
+على الـ oocyte فبالتالي ماعملش حاجة اسمها
+
+58
+00:04:11,140 --> 00:04:15,020
+separation شو يعني separation؟ يعني ما بقوم بفصل و
+
+59
+00:04:15,020 --> 00:04:18,180
+الله قطرة لل first polar body و قطرة لل second
+
+60
+00:04:18,180 --> 00:04:21,500
+polar body عشان بقول ليه كده بقول ان ال fish
+
+61
+00:04:21,500 --> 00:04:24,280
+technique it is not essentially to place the first
+
+62
+00:04:24,280 --> 00:04:26,660
+polar body and the second polar body in different
+
+63
+00:04:26,660 --> 00:04:30,120
+droplets يعني ممكن أضيفهم مع بعض لإنه حكيت في
+
+64
+00:04:30,120 --> 00:04:32,640
+البداية أن ال first polar body و ال second polar
+
+65
+00:04:32,640 --> 00:04:38,140
+bodyهي عبارة عن مادة وراثية متعلقة بويضة واحدة
+
+66
+00:04:38,140 --> 00:04:42,380
+تعود إلى الأم فأي defect له علاقة بالأم maternal
+
+67
+00:04:42,380 --> 00:04:46,660
+defect فما بحتاج أني أفرق ال polar body الأول عن
+
+68
+00:04:46,660 --> 00:04:50,580
+ال polar body التاني و مجرد بعمل biopsy بحطهم في
+
+69
+00:04:50,580 --> 00:04:54,370
+نفس القطرة أو بنقلهمفي نفس القطرة as they can be
+
+70
+00:04:54,370 --> 00:04:58,810
+visualized during fluorescent evaluation هذا
+
+71
+00:04:58,810 --> 00:05:01,230
+بالنسبة إلى ال polar body و second polar body
+
+72
+00:05:01,230 --> 00:05:06,450
+عملية ال transfer الخاصة فيهم فبالتالي مش مهم عندي
+
+73
+00:05:06,450 --> 00:05:09,710
+أفصل ما بينهم due to small cytoplasmic content of
+
+74
+00:05:09,710 --> 00:05:15,050
+polar body a special pretreatment like hypoosmatic
+
+75
+00:05:15,050 --> 00:05:19,690
+swelling or proteinase treatment prior fish is not
+
+76
+00:05:19,690 --> 00:05:24,440
+necessaryمعنى آخر أن عملية ال fish technique أو
+
+77
+00:05:24,440 --> 00:05:27,440
+الخاصة بالخلينا نسميها أن ال polar body لما نبدأ
+
+78
+00:05:27,440 --> 00:05:30,980
+أعمله fish technique مش لازم أعمل حاجة بتسميها
+
+79
+00:05:30,980 --> 00:05:34,460
+pretreatment قبل ال testing أو pretreatment قبل ال
+
+80
+00:05:34,460 --> 00:05:38,800
+analysis يعني مش مطلوب مني أعمل swelling باستخدام
+
+81
+00:05:38,800 --> 00:05:42,540
+ال hypo osmotic swelling test لل polar body مش
+
+82
+00:05:42,540 --> 00:05:46,470
+مطلوب أعمل ما يُعرف باسم ال proteinaseTreatment لـ
+
+83
+00:05:46,470 --> 00:05:50,610
+Polar Body قبل عملية Fish Technique سبب ببساطة أن
+
+84
+00:05:50,610 --> 00:05:53,750
+كمية الـCytoplasma الموجودة في Polar Body كمية
+
+85
+00:05:53,750 --> 00:05:58,430
+قليلة جدا فهذا يسمح لنا بإجراء الفحص مباشرة دون أي
+
+86
+00:05:58,430 --> 00:06:01,970
+خطوة من خطوات المعالجة قبل عملية الـFish Technique
+
+87
+00:06:01,970 --> 00:06:06,670
+For transfer into the glass slide polar body of
+
+88
+00:06:06,670 --> 00:06:09,410
+one oocyte are removed from their drop and
+
+89
+00:06:09,410 --> 00:06:14,210
+transferred intointo tin drop 0.2ml of water
+
+90
+00:06:14,210 --> 00:06:16,730
+placed on the cleaning glass slide يعني هالوقت
+
+91
+00:06:16,730 --> 00:06:20,750
+بتدبدأ أعمل الفحص باخد واحد من ال polar body بضعه
+
+92
+00:06:20,750 --> 00:06:25,060
+في قطرة تحتوى على 0.2ملي لتر من الماء تقريبا يعني
+
+93
+00:06:25,060 --> 00:06:27,800
+200 ميكرو لتر water خدوا بالكوا لما اقول water
+
+94
+00:06:27,800 --> 00:06:30,920
+يعني ultra pure water في كل شيء له علاقة بال
+
+95
+00:06:30,920 --> 00:06:34,460
+molecular biology او ال emperiology small volume
+
+96
+00:06:34,460 --> 00:06:39,020
+مهم جدا طب ليش انا بستخدم 200 micro أو 0.2 ملي لتر
+
+97
+00:06:39,020 --> 00:06:43,040
+من ال water لأنه مهم جدا فيهالمساعدة للـ Polar
+
+98
+00:06:43,040 --> 00:06:45,520
+Body المساعدة للـ Polar Body ان يصيله Attachment
+
+99
+00:06:45,520 --> 00:06:49,120
+مع الـ Glass خلال عملية الـ Drying طالما انا حطيت
+
+100
+00:06:49,120 --> 00:06:52,080
+200 Micro وضفت فيها الـ Polar Body حسيب هذا الـ
+
+101
+00:06:52,080 --> 00:06:56,980
+GIF عملية الـ Drying تعمل عملية Attachment او
+
+102
+00:06:56,980 --> 00:07:01,820
+Fixation بتشتغل ك Fixation Step أو Fixative Step
+
+103
+00:07:01,820 --> 00:07:05,920
+فتعمل Fixation للـ Polar Body في الـ Glass Slide
+
+104
+00:07:05,920 --> 00:07:09,080
+فبالتالي الـ Polar Body بيصير ثابت اي عملية
+
+105
+00:07:09,080 --> 00:07:12,920
+Removing او Washing بيصير له عمليةdrilling أو
+
+106
+00:07:12,920 --> 00:07:16,600
+removing خلاص صار له عملية attachment مع ال glass
+
+107
+00:07:16,600 --> 00:07:19,880
+slide placing the polar body directly at the
+
+108
+00:07:19,880 --> 00:07:22,860
+bottom of the slide will prevent floating and
+
+109
+00:07:22,860 --> 00:07:25,780
+rupture of the polar body انا وانا برفع ال polar
+
+110
+00:07:25,780 --> 00:07:29,080
+body و بنقله الى القطرة التي تحتوى على 200 micro
+
+111
+00:07:29,080 --> 00:07:34,120
+liter من الماء بكون دائما في بالي ان انا اضع ال
+
+112
+00:07:34,120 --> 00:07:37,600
+polar body في اسفل القطرة مش ارميها على سطح القطرة
+
+113
+00:07:37,600 --> 00:07:43,050
+لأ بده ادخل بال needle في القطرةبتأكد إن أنا وضعته
+
+114
+00:07:43,050 --> 00:07:48,250
+بأقرب مسافة من ال slide علشان هذا بمنع ال polar
+
+115
+00:07:48,250 --> 00:07:51,030
+body أن يصير floating و بيساعد على عملية ال
+
+116
+00:07:51,030 --> 00:07:54,870
+fixation بشكل كبير جدا لأن لو صار عملية floating
+
+117
+00:07:54,870 --> 00:07:59,230
+على ال polar body احتمالية فقدره بتكون أكبر بكثير
+
+118
+00:07:59,230 --> 00:08:02,670
+The drying process must be observed under a
+
+119
+00:08:02,670 --> 00:08:05,350
+stereomicroscope and the final location of the
+
+120
+00:08:05,350 --> 00:08:09,010
+polar body after air dries should be markedبمعنى
+
+121
+00:08:09,010 --> 00:08:13,250
+آخر إن بدي أسرع عملية ال drying باخد ال glass اللي
+
+122
+00:08:13,250 --> 00:08:16,730
+فيها 200 ميكرو ليتر water و اللي ضيفت فيها ال
+
+123
+00:08:16,730 --> 00:08:20,650
+polar body بضيفها أو بوضعها على ال stereo
+
+124
+00:08:20,650 --> 00:08:24,830
+microscope واحد الميكروسكوبات اللتي تستخدم في
+
+125
+00:08:24,830 --> 00:08:28,990
+مختبر الأجنة طبعا بكون ال light معرض إليها مشكلة
+
+126
+00:08:28,990 --> 00:08:32,900
+مباشرةهذا بيعمل نوع من أنواع الحرارة المقبولة التي
+
+127
+00:08:32,900 --> 00:08:36,520
+تساعد على تبخر الماء بسرعة مما يؤدي إلى تسريح
+
+128
+00:08:36,520 --> 00:08:40,840
+عملية ال fixation خلصت عملية ال fixation باستخدام
+
+129
+00:08:40,840 --> 00:08:45,620
+ال heating مع ال drying بقوم بعمل markering لل
+
+130
+00:08:45,620 --> 00:08:49,080
+polar body مكانه بيجب أطلع على ال slide من الأسفل
+
+131
+00:08:49,080 --> 00:08:53,100
+هي مكان ال polar body بعمله markering بوضع دائرة
+
+132
+00:08:53,100 --> 00:08:56,040
+باستخدام marker معين بشرط أن ال marker حتى ال
+
+133
+00:08:56,040 --> 00:08:59,500
+marker اللي يستخدمفي الـ Polar Body أو في الـ
+
+134
+00:08:59,500 --> 00:09:04,300
+Imperium لازم يكونش volatile علشان مايأذيش ال
+
+135
+00:09:04,300 --> 00:09:08,130
+Imperiumخلصنا من طريقة الـ Fixation الأولى،
+
+136
+00:09:08,130 --> 00:09:11,310
+بإمكاننا عمل Fixation تانية من خلال استخدام
+
+137
+00:09:11,310 --> 00:09:16,350
+Methanol Acidic Acid Solution من خلال تركيزه 3
+
+138
+00:09:16,350 --> 00:09:20,790
+Methanol إلى 1 Microliter Acidic Acid يعني ممكن
+
+139
+00:09:20,790 --> 00:09:25,050
+يحضروا 3 Methanol إلى 1 Methanol Acidic Acid أو
+
+140
+00:09:25,050 --> 00:09:30,130
+100 أو 300 إلى 100 يعني المفروض يكون النسبة 3 إلى
+
+141
+00:09:30,130 --> 00:09:35,730
+1 3 Methanol إلى 1 Acidic Acidبقوم بوضع تقريباً 20
+
+142
+00:09:35,730 --> 00:09:40,650
+أو 30 microliter يعني تلاتة ضرب على الـ polar body
+
+143
+00:09:40,650 --> 00:09:45,190
+هذا بعمل عملية fixation لمدة طبعا فترة زمانية
+
+144
+00:09:45,190 --> 00:09:49,510
+معينةتقريباً تلاتين ثانية اربعين ثانية هذا كنوع من
+
+145
+00:09:49,510 --> 00:09:52,850
+أنواع ال fixation رقم اتنين بعد ما يصيله fixation
+
+146
+00:09:52,850 --> 00:09:56,050
+another fixation after air dried using methanol at
+
+147
+00:09:56,050 --> 00:09:58,770
+room temperature for five minutes يعني عملت تلت
+
+148
+00:09:58,770 --> 00:10:01,190
+أنواع من ال fixation fixation الأول باستخدام ال
+
+149
+00:10:01,190 --> 00:10:05,150
+water والdrying fixation التاني باستخدام تلاتة إلى
+
+150
+00:10:05,150 --> 00:10:08,210
+واحد methanol acidic acid وال fixation التالت وهو
+
+151
+00:10:08,210 --> 00:10:12,570
+ال methanol على room temperature خمسة minutes خلصت
+
+152
+00:10:12,570 --> 00:10:17,540
+كدهتحضير الـ Polar Body لعملية الـ Fish Technique
+
+153
+00:10:17,540 --> 00:10:20,580
+بعد كده الـ Fish Technique هو Protocol يعتمد على
+
+154
+00:10:20,580 --> 00:10:23,900
+الشركة اللي أنا ماخد منها الـ Sequence المحمل
+
+155
+00:10:23,900 --> 00:10:29,800
+عليها ال Prob أو ال Die هذا مافيش فيه اي اختلافكيف
+
+156
+00:10:29,800 --> 00:10:33,280
+انا بده اعمل transfer ل ال polar body عشان اعمل
+
+157
+00:10:33,280 --> 00:10:37,320
+PCR؟ طبعا بالنسبة لل polar body ال transfer for
+
+158
+00:10:37,320 --> 00:10:40,320
+PCR ال differentiation of the first and second
+
+159
+00:10:40,320 --> 00:10:43,820
+polar body is very important لما بده اعمل PCR
+
+160
+00:10:43,820 --> 00:10:46,460
+باستخدام المادة الوراثية المتعلقة بال polar body
+
+161
+00:10:46,820 --> 00:10:50,320
+هنا لازم أفصل ال first polar body عن ال second
+
+162
+00:10:50,320 --> 00:10:53,460
+polar body لأن لو ال defect صارت في ال first polar
+
+163
+00:10:53,460 --> 00:10:56,260
+body إلها معنى ال defect صار في ال second polar
+
+164
+00:10:56,260 --> 00:10:59,720
+body إلها معنى تاني يختلف عن المعنى الأولاني
+
+165
+00:10:59,720 --> 00:11:04,900
+فبالتالي هنا معناه أن الخلية أو البوايضة فيها خلل
+
+166
+00:11:04,900 --> 00:11:08,280
+في القسم الميوز الأول هنا البوايضة فيها خلل في
+
+167
+00:11:08,280 --> 00:11:14,240
+القسم الميوز التاني فبالتالي الخلل ممكن يكون مستمر
+
+168
+00:11:14,240 --> 00:11:17,810
+مع الأجيالفمعنى آخر إذا كان في عندي خلال في ال
+
+169
+00:11:17,810 --> 00:11:23,270
+polar body biopsy الأول معناه قد يكون تم تصحيحه
+
+170
+00:11:23,270 --> 00:11:27,090
+عندما تم إنتاج ال polar body التاني أو لم يتم
+
+171
+00:11:27,090 --> 00:11:30,650
+تصحيحه فاللي بأكد هذا الكلامالـ second polar body
+
+172
+00:11:30,650 --> 00:11:34,830
+biopsy فبالتالي في حالة ال PCR لازم افصل ال first
+
+173
+00:11:34,830 --> 00:11:38,070
+polar body عن ال second polar body therefore the
+
+174
+00:11:38,070 --> 00:11:40,570
+first and the second polar body are released after
+
+175
+00:11:40,570 --> 00:11:45,110
+biopsy in the two different droplets و لازم اغطي
+
+176
+00:11:45,110 --> 00:11:47,810
+ال cover بعد ما اضفه في ال droplets الخاص بال
+
+177
+00:11:47,810 --> 00:11:52,070
+media اعمله covering و اغطي ال drops باستخدام
+
+178
+00:11:52,070 --> 00:11:56,720
+mineral oil علشان احافظ على المادة الوراثيةكما هي
+
+179
+00:11:56,720 --> 00:12:01,280
+وحافظ على البولار بادي بدون أي external effect
+
+180
+00:12:01,280 --> 00:12:06,740
+خلصنا من البولار بادي نيجي لقى ال embryo واللي
+
+181
+00:12:06,740 --> 00:12:09,920
+الكل الناس اللي بتشتغل في هذا المجال بتنيل إلى
+
+182
+00:12:09,920 --> 00:12:13,400
+استخدام ال embryo فيبسي في تشخيص الأمراض الوراثية
+
+183
+00:12:13,400 --> 00:12:19,420
+أو تحديد مرض معين إذا كان الطبيب بتبحث عنه طبعا
+
+184
+00:12:19,420 --> 00:12:23,100
+بالنسبة لل embryoهذه عملية ..عملية critical إلى حد
+
+185
+00:12:23,100 --> 00:12:27,900
+ما بشكل كبير جدا لأن أنا مهمتي هنا أخد خلية من وسط
+
+186
+00:12:27,900 --> 00:12:32,000
+تمام الخلايا أو أخد خاليتين من وسط 32 خلية
+
+187
+00:12:32,000 --> 00:12:36,140
+فبالتالي أي خطأ أثناء ال biopsy معناه rupture و
+
+188
+00:12:36,140 --> 00:12:39,660
+destructure لل embryo يعني أنا كده فشلت في أخذ
+
+189
+00:12:39,660 --> 00:12:43,540
+الخزعة وفشلت في إتمام عملية الحقن المجهر إلى
+
+190
+00:12:43,540 --> 00:12:49,000
+النهاية للحصول على true baby فبالتالي مهم جدا أعرف
+
+191
+00:12:49,000 --> 00:12:53,770
+وقت الخزعةوكم خلية اخد هذا مهم جدا اهم two factor
+
+192
+00:12:53,770 --> 00:12:59,330
+لنجاح عملية ال embryo biopsy حكينا في حاجة اسمة
+
+193
+00:12:59,330 --> 00:13:03,790
+Plastomere وهي كل خلية تظهر بعد اليوم الثاني من
+
+194
+00:13:03,790 --> 00:13:08,000
+الانقسان بسميها Plastomereكل خلية أنا باخدها
+
+195
+00:13:08,000 --> 00:13:12,540
+بسميها embryo biopsy Plastomere biopsy or embryo
+
+196
+00:13:12,540 --> 00:13:16,240
+biopsy is a technique that is performed during IVF
+
+197
+00:13:16,240 --> 00:13:20,340
+when an embryo has arrived at the 6th or 8th cell
+
+198
+00:13:20,340 --> 00:13:24,740
+يعني بعد تلت أيام من القسم يعني معنى الكلام أن ال
+
+199
+00:13:24,740 --> 00:13:28,460
+embryo biopsy لها مسمة أخر هي Plastomere biopsy
+
+200
+00:13:28,460 --> 00:13:32,920
+وهي عبارة عن عملية يتم فيها أخذ خلية واحد أو
+
+201
+00:13:32,920 --> 00:13:37,470
+خاليتينمن جنين يحتوي في الأصل على 6 خلايا على
+
+202
+00:13:37,470 --> 00:13:41,410
+الأقل أو 8 خلايا متى بيصير 6 خلايا أو 8 خلايا؟ لأن
+
+203
+00:13:41,410 --> 00:13:45,590
+هذه فترة في اليوم التالت من الإنقسام الهدف الأساسي
+
+204
+00:13:45,590 --> 00:13:48,990
+للإمبيريوبيبسي هو إزالة صفشا من تشو الإمبيريونيك
+
+205
+00:13:48,990 --> 00:13:53,770
+لجيناتك الدياجنوستيك مثلا من أشهر أنواع الجيناتك
+
+206
+00:13:53,770 --> 00:13:58,270
+الدياجنوستيك الحاجة بيسميها pre-genetic أو pre
+
+207
+00:13:58,270 --> 00:14:01,920
+-genetic diagnosticأو خلّينا نسميه Pre
+
+208
+00:14:01,920 --> 00:14:04,080
+-implantation Genetic Diagnostic اللي حاجة نسميه
+
+209
+00:14:04,080 --> 00:14:07,960
+PGD Pre-implantation Genetic Diagnostic و اللي
+
+210
+00:14:07,960 --> 00:14:13,560
+كانت أول مطاردة في عام 1989 كبداية تم فيها تشقيس
+
+211
+00:14:13,560 --> 00:14:17,840
+بعض الأمراض المتصلة بال X-Chromosome سواء كان
+
+212
+00:14:17,840 --> 00:14:20,620
+dominant أو recessive اللي سمينا X-linked disorder
+
+213
+00:14:20,620 --> 00:14:26,320
+أيضا بعد كده استخدموا الامبروبيوتس 4-6 selection
+
+214
+00:14:27,020 --> 00:14:29,420
+الـ Embryo biopsy هي عبارة عن two-step
+
+215
+00:14:29,420 --> 00:14:33,700
+micromanipulation process تشمل الخطواتين الخطوة
+
+216
+00:14:33,700 --> 00:14:37,120
+الأولى تشمل penetration للزونا بليوسيدا أو
+
+217
+00:14:37,120 --> 00:14:40,780
+partially removing للزونا بليوسيدا علشان انا
+
+218
+00:14:40,780 --> 00:14:46,660
+استطيع ان ادخل للخلية بعد كده بعد ما يصير عندي
+
+219
+00:14:46,660 --> 00:14:51,970
+partially penetration للزونا بليوسيدالازم بعد كده
+
+220
+00:14:51,970 --> 00:14:57,270
+اعمل removing ل one cell او two cells من الخلية
+
+221
+00:14:57,270 --> 00:15:01,810
+إذن هي عبارة عن عملية بتتم بخطواتين الخطوة الأولى
+
+222
+00:15:01,810 --> 00:15:04,290
+partial removing for zona pellucida
+
+223
+00:15:07,620 --> 00:15:14,000
+مؤقت الشغلة التانية بشكل جزء خلينا نسميه بعد كده
+
+224
+00:15:14,000 --> 00:15:18,360
+بدخل بال aspiration needle عشان أجي أعمل حاجة
+
+225
+00:15:18,360 --> 00:15:23,660
+بنسميها aspiration أو removing لل one or more one
+
+226
+00:15:23,660 --> 00:15:28,320
+cells طبعا عدد الخلايا أنا مش اللي بتحكم فيه بشكل
+
+227
+00:15:28,320 --> 00:15:32,740
+عام بل بتحكم فيهطبيعة الـ embryo أكم خلية موجودة
+
+228
+00:15:32,740 --> 00:15:35,760
+في الـ embryo هذا اللي يتحكم فيه بالنسبة للبيوبس
+
+229
+00:15:35,760 --> 00:15:39,200
+التكنيكي ممكن أنا أعمل penetration لزونا بليوسيدا
+
+230
+00:15:39,200 --> 00:15:41,860
+mechanical زي ما احنا شوفنا في الـ assistant
+
+231
+00:15:41,860 --> 00:15:46,080
+hatching و بالفيديو chemical باستخدام بعض المواد
+
+232
+00:15:46,080 --> 00:15:49,980
+الكيميائية وهي عبارة عن مواد في الغالب تكون acidic
+
+233
+00:15:49,980 --> 00:15:54,640
+زي الـ triode acid هذا أخدناها في الـ polar body
+
+234
+00:15:54,640 --> 00:15:58,670
+biopsy إذا في عندي mechanical وفي عنديكيميكال وفي
+
+235
+00:15:58,670 --> 00:16:03,070
+عندى الحاجة اللى بنسميها ال laser hatching إن أنا
+
+236
+00:16:03,070 --> 00:16:06,910
+بستخدم طريقة ال laser وإني بعمل firing بدبث معين
+
+237
+00:16:06,910 --> 00:16:10,970
+بعدد معين Plastomera Remove قولنا إيه إيه ال
+
+238
+00:16:10,970 --> 00:16:14,190
+Plastomera؟ حكى إن Plastomera هي كل خلية موجودة
+
+239
+00:16:14,190 --> 00:16:17,670
+داخل ال embryo بعد اليوم التاني the most
+
+240
+00:16:17,670 --> 00:16:20,350
+frequently used method for Plastomera Remove is
+
+241
+00:16:20,350 --> 00:16:24,710
+aspiration هذه هي الطريقة اللى تستخدم بشكل عالميش
+
+242
+00:16:24,710 --> 00:16:29,960
+بط بتدخل بال forceps مثلا و بسحدالبلاستوميرا لأ،
+
+243
+00:16:29,960 --> 00:16:34,340
+هي عبارة عن suction tube أو aspiration needle بدخل
+
+244
+00:16:34,340 --> 00:16:39,700
+داخل البويضة بعد عملية التعرية أو إزالة جزء من الـ
+
+245
+00:16:39,700 --> 00:16:42,660
+zona pellucida من نفس المكان اللي أزلت منه zona
+
+246
+00:16:42,660 --> 00:16:46,140
+pellucida بدخل بال aspiration needle وبعمل
+
+247
+00:16:46,140 --> 00:16:50,580
+aspiration or suction ل one or two cell after
+
+248
+00:16:50,580 --> 00:16:53,380
+remove the cell, the developed embryo is placed
+
+249
+00:16:53,380 --> 00:16:56,800
+back in the culture media andturned to the
+
+250
+00:16:56,800 --> 00:16:59,760
+incubator where it can be resumed it's normal
+
+251
+00:16:59,760 --> 00:17:02,440
+growth and development طبعا هذه العملية .. عملية
+
+252
+00:17:02,440 --> 00:17:05,120
+ال aspiration بتكون في اليوم التاني .. عفوا في
+
+253
+00:17:05,120 --> 00:17:08,100
+اليوم التالت .. في اليوم الرابع بناء على عدد
+
+254
+00:17:08,100 --> 00:17:10,940
+الخلايا الموجودة داخل الجنين بعد ما أخد الخلايا
+
+255
+00:17:10,940 --> 00:17:14,320
+المطلوبة .. الخلية أو التنتين مباشرة برجع الجنين
+
+256
+00:17:14,320 --> 00:17:17,380
+في ال petri dish أو عفوا برجع الجنين الموجود في ال
+
+257
+00:17:17,380 --> 00:17:22,060
+petri dish كله في ال petri dish الموجود كامل ك one
+
+258
+00:17:22,060 --> 00:17:26,670
+unit في ال incubatorوبسمح للجنين إنه في هذه اللحظة
+
+259
+00:17:26,670 --> 00:17:32,150
+يستكمل عملية نموه وانقسامه عشان يصل إلى 16 خلية و
+
+260
+00:17:32,150 --> 00:17:38,510
+2 تلاتية خلية و يصل لمرحلة الموريلا أيضا هذه الشكل
+
+261
+00:17:38,510 --> 00:17:44,690
+اللي أنا بقصده في الخطوة الأولى عملت عملية holding
+
+262
+00:17:44,690 --> 00:17:52,700
+ل ال embryo بتكون من 1,2,3,4,5,6 حوالي 6 خلاياعملت
+
+263
+00:17:52,700 --> 00:17:55,980
+له holding في ال holder طيبت بعدين دخلت بال needle
+
+264
+00:17:55,980 --> 00:17:59,440
+عشان أعمل حاجة بنسميها mechanical zoonapelucida
+
+265
+00:17:59,440 --> 00:18:04,300
+removing أو mechanical hatching بعد كده حكيت أنه
+
+266
+00:18:04,300 --> 00:18:08,400
+بعمل releasing إلها من ال holder tube و باخدها و
+
+267
+00:18:08,400 --> 00:18:13,440
+بحك أو بعمل عملية احتكاك بسيط في أسفل ال holder
+
+268
+00:18:13,440 --> 00:18:16,300
+tube علشان أعمل removing لهذه المنطقة
+
+269
+00:18:19,740 --> 00:18:22,800
+طبعا بعد ما أعمل removing بدخل بال aspiration
+
+270
+00:18:22,800 --> 00:18:28,340
+needle و بعمل aspiration ل one tube إذن في هذه
+
+271
+00:18:28,340 --> 00:18:31,860
+العملية يتم عمل partial removing للـ zona
+
+272
+00:18:31,860 --> 00:18:36,080
+pellucida كما هو موضح في الصورة الأولى ثم بعد ذلك
+
+273
+00:18:36,080 --> 00:18:40,080
+الدخول بال aspiration needle من المنطقة التي تم
+
+274
+00:18:40,080 --> 00:18:43,360
+عمل فيها partial removing للـ zona pellucida و عمل
+
+275
+00:18:43,360 --> 00:18:48,460
+suction أو aspiration ل one cell من الblastomera
+
+276
+00:18:48,460 --> 00:18:53,380
+الموجودةهذا بالنسبة لعملية الـ Empyrean biopsy
+
+277
+00:18:53,380 --> 00:18:59,500
+سؤال مهم بالنسبة لـ Empyrean biopsy شو أهم عوامل
+
+278
+00:18:59,500 --> 00:19:03,280
+بتتحكم فيها؟ أقول إن الـ timing متى أعمل زونة
+
+279
+00:19:03,280 --> 00:19:07,200
+بليستر removing أو متى أعمل Empyrean biopsy في أي
+
+280
+00:19:07,200 --> 00:19:11,840
+يوم وعدد الخلايا اللي أنا جادر أخدها فبالتالي ال
+
+281
+00:19:11,840 --> 00:19:14,820
+timing of biopsy domestically Vigestige biopsy
+
+282
+00:19:14,820 --> 00:19:18,360
+taking place on the third morning followed of
+
+283
+00:19:18,520 --> 00:19:23,080
+Insemination بمعنى آخر انه انا في معظم الحالات لو
+
+284
+00:19:23,080 --> 00:19:25,980
+بدي اعمل embryo biopsy بدي اعملها في اليوم التالت
+
+285
+00:19:25,980 --> 00:19:30,340
+من عملية الاجزي يعني بمعنى آخر لو صارت عملية ال
+
+286
+00:19:30,340 --> 00:19:35,260
+injection في اليوم الأول و هو يوم السبت السبت خلص
+
+287
+00:19:35,260 --> 00:19:39,260
+الأحد يوم الأثنين ممكن ابدأ اعمل embryo biopsy
+
+288
+00:19:39,260 --> 00:19:43,620
+وهذا ال protocol معظم مختبرات الاجزي او مختبرات ال
+
+289
+00:19:43,620 --> 00:19:47,100
+IVF ال IVF بتعتمد عليه انه في اليوم التالت هو
+
+290
+00:19:47,100 --> 00:19:52,660
+اليوماللي مفضل لعمل ال biopsy طبعاً لما نبدأ أجي
+
+291
+00:19:52,660 --> 00:19:57,740
+أعمل biopsy مهم جدا أن بعضهم بيعمل biopsy في اليوم
+
+292
+00:19:57,740 --> 00:20:01,500
+الأول فبالتالي إذا كانت النتيجة بتحتاج إلى فترة
+
+293
+00:20:01,500 --> 00:20:05,400
+زمنية طويلة جدا يومين أو تلاتة علشان تطلع عن نتيجة
+
+294
+00:20:05,400 --> 00:20:09,980
+نتيجة ال genetic testing فبرجع في اليوم الخامس
+
+295
+00:20:09,980 --> 00:20:13,700
+والله إذا كان النتيجة بتطلع خلال 24 ساعة برجع في
+
+296
+00:20:13,700 --> 00:20:19,270
+اليومالرابع يعني مهم جدا ان عملية الترجية تحدث بعد
+
+297
+00:20:19,270 --> 00:20:23,290
+يومين كحد اقصى او تلاتة كحد اقصى من عملية ال
+
+298
+00:20:23,290 --> 00:20:25,610
+embryo biopsy اذا انا عملت ال embryo biopsy في
+
+299
+00:20:25,610 --> 00:20:29,470
+اليوم التالت في اليوم التالت من عملية ال
+
+300
+00:20:29,470 --> 00:20:34,170
+insemination النقطة التانية المهمة جدا ال number
+
+301
+00:20:34,170 --> 00:20:38,410
+of cells اكمل Plastomere انا ممكن اخد من الbiopsy
+
+302
+00:20:38,410 --> 00:20:45,610
+او من ال embryo هذاأكم او أكم cells موجودة داخل ال
+
+303
+00:20:45,610 --> 00:20:50,630
+embryo هاي موجود 6 موجود 8 موجود 16 موجود 32 كل ما
+
+304
+00:20:50,630 --> 00:20:54,110
+زاد عدد الخلايا كل ما كان عندي إمكانية أن أاخد
+
+305
+00:20:54,110 --> 00:21:00,410
+بيبسي 2 و 3 و 4 فهذا مهم جدا في معظم أو العديد من
+
+306
+00:21:00,410 --> 00:21:04,770
+مختبرات ال IVF بيعتوا second blastomera is removed
+
+307
+00:21:04,770 --> 00:21:10,270
+from embryo having 7 or more cellsيعني أي embryo
+
+308
+00:21:10,270 --> 00:21:14,870
+بيحتوي على ستة أو سبع خلايا أو أكتر كل المختبرات
+
+309
+00:21:14,870 --> 00:21:17,630
+أو عدد خليني أسميها من المختبرات بياخد خليتين يعني
+
+310
+00:21:17,630 --> 00:21:21,650
+بياخد two blastomeras و بيخضعهم لل genetic testing
+
+311
+00:21:21,650 --> 00:21:25,890
+بعضهم لأ بياخد واحدة بقولك لأنه بعض الدراسات جلت
+
+312
+00:21:25,890 --> 00:21:29,350
+أنه كل ما زاد عدد ال pipes المأخوذة كل ما كانت لها
+
+313
+00:21:29,350 --> 00:21:33,950
+تأثير سلبي على تطور و نمو الجديد في بعض الأحيان أو
+
+314
+00:21:33,950 --> 00:21:37,740
+بعض الدراسات جلت لأ مافيش منه الكلام هذالأن الجنين
+
+315
+00:21:37,740 --> 00:21:42,660
+قادر إنه ينمو ويتأقلم على الوضع الجديد فبالتالي
+
+316
+00:21:42,660 --> 00:21:49,220
+القرار الأساسي اللي بحكمني أكم بيوبسي أخد أو أكم
+
+317
+00:21:49,220 --> 00:21:54,660
+Plastomere أخد واحدة أو تنتين يعتمد على عدة عوامل
+
+318
+00:21:54,660 --> 00:21:57,860
+العامل الأول الـ embryo cell number أكم خلية
+
+319
+00:21:57,860 --> 00:22:02,780
+موجودة داخل ال embryo والشغل التاني ال testing
+
+320
+00:22:02,780 --> 00:22:05,660
+اللي أنا بدي أعمله و ال diagnostic اللي بدي أعمله
+
+321
+00:22:05,920 --> 00:22:09,280
+أنا ماحتاج جداش كمية من المادة الوراثية يعني مش
+
+322
+00:22:09,280 --> 00:22:13,760
+منطقي و الله انا بدي اعمل خمس فحوصات وراثية فال
+
+323
+00:22:13,760 --> 00:22:18,100
+one embryo او one biopsy او one plasomera الكمية
+
+324
+00:22:18,100 --> 00:22:21,560
+المادة الوراثية الموجودة فيها لن تكفي فمش منطقي
+
+325
+00:22:21,560 --> 00:22:25,060
+اروح اعمل بس اتنين واسيب الخمسة او باجد الخمس
+
+326
+00:22:25,060 --> 00:22:27,880
+فحوصات المطلوبة ففي نفس اللحظة باخد اتنين
+
+327
+00:22:27,880 --> 00:22:31,600
+plasomera او تلاتة plasomera علشان اضمن ان الكمية
+
+328
+00:22:31,600 --> 00:22:35,550
+المتوفرة لدي من المادة الوراثية الخاصة بالجنينتكفي
+
+329
+00:22:35,550 --> 00:22:40,490
+لعمل جميع الفحوصات الوراثية المطلوبة remove of two
+
+330
+00:22:40,490 --> 00:22:44,030
+cells should only be considered one embryo with
+
+331
+00:22:44,030 --> 00:22:47,770
+six or more cells يعني keep it in your mind as
+
+332
+00:22:47,770 --> 00:22:53,450
+note ان عزل خلية واحدة plus تميرة او خليتين يجب ان
+
+333
+00:22:53,450 --> 00:22:58,090
+تكون او تحدث على امبريو يحتوي على الأقل ست خلايا
+
+334
+00:22:58,090 --> 00:23:02,950
+اول الفحوصات اللي انا ممكن اشتغلها فحص بنسمي ال
+
+335
+00:23:02,950 --> 00:23:08,720
+BGD وهوimplantation genetic testing من اسمه تشخيص
+
+336
+00:23:08,720 --> 00:23:14,720
+جيني قبل الإنغراس أو قبل الجرجعة وهو أحد الفحوصات
+
+337
+00:23:14,720 --> 00:23:19,280
+الوراثية المنتشرة في المراكز التحقن المجهري أو
+
+338
+00:23:19,280 --> 00:23:23,680
+التلقيح الصناعي والتي تعتمد على تشخيص أمراض معينة
+
+339
+00:23:23,680 --> 00:23:29,040
+لها علاقة بعائلة معينة يعني بمعنى آخر زي
+
+340
+00:23:29,040 --> 00:23:31,340
+الهموفيليا منتشرة في عائلة معينة ال sickle cell
+
+341
+00:23:31,340 --> 00:23:34,630
+منتشرة في عائلة معينةالأنيميا بأنواعها متشرة في
+
+342
+00:23:34,630 --> 00:23:39,450
+بعض العائلات فبدي أنا أرجّق جنين هذا الجنين لا
+
+343
+00:23:39,450 --> 00:23:43,990
+يحمل الجين المسؤول عن المرض يعني جنين normal بنسبة
+
+344
+00:23:43,990 --> 00:23:47,630
+كبيرة جدا during PGD the genetic analysis is done
+
+345
+00:23:47,630 --> 00:23:51,490
+for of the single cell from 8 cell embryo نفس
+
+346
+00:23:51,490 --> 00:23:54,930
+القصة يقول إن أنا بعمل analysis للمادة الوراثية
+
+347
+00:23:54,930 --> 00:23:58,730
+المأخوذة من خلية واحدة من ال embryo يحتوي على 8
+
+348
+00:23:58,730 --> 00:24:02,390
+خلاياعشان كده قلنا فيما سبق أنه أقل شيء من 6 إلى 7
+
+349
+00:24:02,390 --> 00:24:05,830
+خلايا هو الجنين المسموح له يخضع للـ Empyrean
+
+350
+00:24:05,830 --> 00:24:10,510
+Biopsy الـ PGD هي عبارة عن الـ procedure تحدث بعد
+
+351
+00:24:10,510 --> 00:24:14,870
+عملية ال fertilization وتحدث قبل عملية ال
+
+352
+00:24:14,870 --> 00:24:18,610
+implantation وهذا أمر طبيعي جدا جدا عشان أنا أشخص
+
+353
+00:24:18,610 --> 00:24:22,730
+أي defect في المادة الوراثية المتعلقة بالجنين وليس
+
+354
+00:24:22,730 --> 00:24:25,890
+المتعلقة بالأب والأم لأن هذه المادة الوراثية الـ
+
+355
+00:24:25,890 --> 00:24:30,810
+Plastomereهي مادة وراثية خاصة بالجنين كحد عام أو
+
+356
+00:24:30,810 --> 00:24:36,090
+بشكل خاص جدا الـ PGD لا يُعتبر therapeutic
+
+357
+00:24:36,090 --> 00:24:40,650
+procedure بمعنى آخر إنه أنا برغم إنه عملت PGD ما
+
+358
+00:24:40,650 --> 00:24:45,430
+في عندي جارانتي إنه الطفل المرجع يكون سالم بنسبة
+
+359
+00:24:45,430 --> 00:24:49,530
+100% يكون سليم بنسبة 100% فبالتالي
+
+360
+00:24:54,410 --> 00:24:58,830
+مادة أو عملية الـ BGD هي عبارة عن عملية تشخيصية
+
+361
+00:24:58,830 --> 00:25:03,530
+محظة بالشكل الأول ومن الدرجة الأولى لا تعتبر عملية
+
+362
+00:25:03,530 --> 00:25:07,410
+علاجية لأنه لا يتم حدوث تغير في المادة الوراثية
+
+363
+00:25:07,410 --> 00:25:12,090
+المتعلقة بالجنين ما بدخل جين مقابل جين هذا إشي
+
+364
+00:25:12,090 --> 00:25:17,810
+تاني طبعا الـ BGD مرت بتسميات مختلفة منها الـ BGT
+
+365
+00:25:17,810 --> 00:25:21,050
+وهي الـ Preimplantation Genetic Testing بعد أن
+
+366
+00:25:21,050 --> 00:25:26,980
+تطورت إلى تشخيص أنبلودي فسموهاBGT-A يعني بلودي بعد
+
+367
+00:25:26,980 --> 00:25:30,600
+ان اتطورت الى الـ BGT-M اللي لها علاقة بالـ Single
+
+368
+00:25:30,600 --> 00:25:33,760
+Gene Defect أو الـ Monogenetic بعد ان اتطورت الى
+
+369
+00:25:33,760 --> 00:25:36,880
+الـ BGT-SR اللي لها علاقة بالـ Structure
+
+370
+00:25:36,880 --> 00:25:42,140
+Rearrangement فبالاصل هي عبارة عن BGT or BGT بناء
+
+371
+00:25:42,140 --> 00:25:46,420
+على ماذا تستخدم أو لماذا تستخدم أو في ماذا تستخدم
+
+372
+00:25:46,790 --> 00:25:50,110
+إذا كانت تستخدم لتشخيص الانبلودي، بضيف حرف A إذا
+
+373
+00:25:50,110 --> 00:25:53,050
+كانت تستخدم لتشخيص الـ monogenetic أو single gene
+
+374
+00:25:53,050 --> 00:25:57,190
+defect، بضيف M إذا كانت تستخدم لتشخيص الكرومزومة
+
+375
+00:25:57,190 --> 00:26:01,950
+الـ Structural Rearrangement بضيف BGTSR Single
+
+376
+00:26:01,950 --> 00:26:06,190
+Structural Rearrangement مين ممكن يستفيد من الـ
+
+377
+00:26:06,190 --> 00:26:11,120
+BGT؟ عدةحالات ممكن تستفيد من الـ BGD أول حالة ان
+
+378
+00:26:11,120 --> 00:26:16,660
+الكابلز اللي عندهم career for sex link disorder او
+
+379
+00:26:16,660 --> 00:26:19,360
+genetic disorder اللي بنسميه sex link genetic
+
+380
+00:26:19,360 --> 00:26:22,940
+disorder الكاريار لل single gene disorder الناس
+
+381
+00:26:22,940 --> 00:26:25,720
+اللي عندهم الكرموزومة الأبطول مالتيال women اللي
+
+382
+00:26:25,720 --> 00:26:29,300
+عمرها أكتر من 38 سنة لإن عرض ال structure
+
+383
+00:26:29,300 --> 00:26:33,100
+rearrangement بتكون أكتر ال chance لظهورها ال
+
+384
+00:26:33,100 --> 00:26:38,260
+women have severe .. or several خلينا نسميها
+
+385
+00:26:38,260 --> 00:26:42,900
+miscarriage السيدات اللي عندهم pregnancy lose بشكل
+
+386
+00:26:42,900 --> 00:26:46,860
+مستمر السيدات اللي عندهم chromosomal abnormality
+
+387
+00:26:46,860 --> 00:26:51,940
+بشكل واضحو تم تشخيصهم بالـ chromosomal abnormality
+
+388
+00:26:51,940 --> 00:26:55,080
+بشكل واضح قبل عملية الحمل فبالتالي ممكن هذه الحالة
+
+389
+00:26:55,080 --> 00:26:59,820
+تنتقل للجنين فبالتالي بعمل BGD للجنين علشان أتأكد
+
+390
+00:26:59,820 --> 00:27:03,980
+أن هذه الحالة مش موجودة عنده أيضا ال BGD ممكن
+
+391
+00:27:03,980 --> 00:27:08,040
+أستخدمها لل sex selection ال BGD ممكن أعملها لل
+
+392
+00:27:08,040 --> 00:27:11,440
+balancing for sex يعني بدي family تبتعد من اتنين
+
+393
+00:27:11,440 --> 00:27:15,480
+ذكور اتنين اناف هذا ما يسمى balanceالـ PGD ممكن
+
+394
+00:27:15,480 --> 00:27:20,100
+تحدث للـ couples اللي عندهم IVF فاليار أكتر من تلت
+
+395
+00:27:20,100 --> 00:27:25,740
+مرات man with some of sperm abnormality سواء كانت
+
+396
+00:27:25,740 --> 00:27:28,800
+عنده sperm abnormality في الـ head في الميتاكندرية
+
+397
+00:27:28,800 --> 00:27:34,580
+في الـ chromatin abnormality في الكرومزوم
+
+398
+00:27:34,580 --> 00:27:38,560
+كوندنسيشن هذه كلها ممكن أنا أستخدم PGD عشان أتأكد
+
+399
+00:27:38,560 --> 00:27:41,700
+أن الحالة المرضية مش موجودة الـ Unexplained
+
+400
+00:27:41,700 --> 00:27:45,340
+infertility ممكن أستخدم فيها PGDY chromosome
+
+401
+00:27:45,340 --> 00:27:50,560
+deletion found in 5-10% of male with those pair
+
+402
+00:27:50,560 --> 00:27:54,180
+count يعني ممكن انا اعمل Y chromosome deletion او
+
+403
+00:27:54,180 --> 00:27:58,740
+micro deletion باستخدام ال BGD صحيح ممكن ان اشوف
+
+404
+00:27:58,740 --> 00:28:01,420
+ال chromosome هذا او ال micro deletion الخاصة
+
+405
+00:28:01,420 --> 00:28:05,240
+بالchromosome Y موجودة في ال embryo خاصة اذا كان
+
+406
+00:28:05,240 --> 00:28:08,340
+ال embryo طبعا male اذا كان الجينات المسؤولة عن
+
+407
+00:28:08,340 --> 00:28:11,780
+ظهور ال reproductive system for male موجودة في ال
+
+408
+00:28:11,780 --> 00:28:15,580
+embryoأو الجينات المسؤولة عن الـ spermatogenesis
+
+409
+00:28:15,580 --> 00:28:18,820
+موجودة في الـ embryo فبالتالي هذا الـ embryo
+
+410
+00:28:18,820 --> 00:28:23,660
+هيتحول لميل فيما بعد فبالتالي ممكن أنا أبحث عن ال
+
+411
+00:28:23,660 --> 00:28:27,480
+micro deletion أو بنسميها Y كرمزوم micro deletion
+
+412
+00:28:27,480 --> 00:28:31,160
+abnormality إذا موجودة و لا مش موجودة و خاصة في
+
+413
+00:28:31,160 --> 00:28:35,000
+الميل اللي عندهم low sperm count اللي سمناها
+
+414
+00:28:35,000 --> 00:28:40,020
+Oligosperm هنعرف إيش يعني ما هي الجينات المحمولة
+
+415
+00:28:40,020 --> 00:28:44,500
+على ال Y كرمزومأول الفحوصات التي يمكن أن تشخص
+
+416
+00:28:44,500 --> 00:28:48,380
+باستخدام الـ BGD فحص بنسميه الـ Anplody الـ
+
+417
+00:28:48,380 --> 00:28:52,960
+Anplody و أكيد كلنا بنعرفها هي عبارة عن وجود مشكلة
+
+418
+00:28:52,960 --> 00:28:56,720
+في عدد الكرمزومات وجود مشكلة في عدد الكرمزومات
+
+419
+00:28:56,720 --> 00:29:00,240
+يعني عدد الكرمزومات مش طبيعي سواء هذه المشكلة
+
+420
+00:29:00,240 --> 00:29:03,120
+زيادة في عدد الكرمزومات بالكرمزوم واحد أو اتنين أو
+
+421
+00:29:03,120 --> 00:29:06,880
+نقصان في عدد الكرمزومات بالكرمزوم واحد او اتنين أو
+
+422
+00:29:06,880 --> 00:29:12,110
+أكتر أو أقل هذا بنسميها Anplody زيادة أو نقصانتؤدي
+
+423
+00:29:12,110 --> 00:29:16,310
+إلى اختلاف في عدد الكروموزوم يعني abnormality in
+
+424
+00:29:16,310 --> 00:29:19,770
+the number of chromosomes Anaploidy occur during
+
+425
+00:29:19,770 --> 00:29:22,930
+cell division when the chromosomes don't separated
+
+426
+00:29:22,930 --> 00:29:26,870
+probably between the two cells يعني الهدف الأساسي
+
+427
+00:29:26,870 --> 00:29:31,010
+أو السبب الأساسي من ال Anaploidy يعبر عن خلل في
+
+428
+00:29:31,010 --> 00:29:34,130
+انقسام الخلية عندما في مرحلة من مراحل الخلية
+
+429
+00:29:34,130 --> 00:29:38,680
+وخصوصا في مرحلة الانافيزإنه بيصير عندي فصل
+
+430
+00:29:38,680 --> 00:29:42,780
+للكرمزومة عن بعض البعض بشكل غير صحيح فخلية بتاخد
+
+431
+00:29:42,780 --> 00:29:46,560
+عدد زيادة وخلية بيكون فيها عدد ناقص من الكرمزومة
+
+432
+00:29:46,560 --> 00:29:49,380
+الـ Abnormality most frequently caused of
+
+433
+00:29:49,380 --> 00:29:53,380
+spontaneous abortion بناء على دراسات معينة يوجد
+
+434
+00:29:53,380 --> 00:29:58,960
+عديد من الأشكال المتعلقة بالأنبلودي زي تريزوم 21،
+
+435
+00:29:58,960 --> 00:30:05,010
+تريزوم 18، الادوارووالـ Trisomy 13 كمان من أشهر
+
+436
+00:30:05,010 --> 00:30:07,910
+أنواع الانبلودي طبعاً في انبلودي كتير بس احنا
+
+437
+00:30:07,910 --> 00:30:12,710
+مانشوفهاش لإنه بيصيلها defect قبل الميلاد The
+
+438
+00:30:12,710 --> 00:30:16,810
+impact of a chromosome abnormality شو بتأثر أو على
+
+439
+00:30:16,810 --> 00:30:19,190
+شو بتأثر الكرمزومات abnormality؟ شو ال influence
+
+440
+00:30:19,190 --> 00:30:22,510
+تبعتها؟ بتأثر على .. بتؤدي إلى .. خلّيني أسمي أو
+
+441
+00:30:22,510 --> 00:30:25,770
+تأثيرها يؤدي إلى decrease في ال embryo transfer
+
+442
+00:30:25,770 --> 00:30:29,490
+طالما أنا عندي خمسة embryo في عندهم تلاتة embryo
+
+443
+00:30:31,100 --> 00:30:34,160
+فبالتالي مش منطق ارجعهم و انا اكتشفت ان فيهم عندهم
+
+444
+00:30:34,160 --> 00:30:37,760
+انبلوه دي فبرجع اتنين فصار عندي reduction في ال
+
+445
+00:30:37,760 --> 00:30:41,900
+rate of embryo transfer implantation failure ممكن
+
+446
+00:30:41,900 --> 00:30:46,860
+تصير في عندي pregnancy loss بشكل مستمر وارد او
+
+447
+00:30:46,860 --> 00:30:51,780
+miscarriage في عندي birth defect ممكن الطفل يولد و
+
+448
+00:30:51,780 --> 00:30:57,080
+هو ميت maternal and physical problem in offspring
+
+449
+00:30:57,080 --> 00:31:02,210
+ممكن الأجيالالجيل يورّف الـ abnormality للجيل
+
+450
+00:31:02,210 --> 00:31:06,430
+التاني فبتبقى سما غاهرة في هذه العائلة هذه كلها
+
+451
+00:31:06,430 --> 00:31:10,590
+تعتبر the impact of a chromosome abnormality سؤال
+
+452
+00:31:10,590 --> 00:31:14,330
+بيطرح نفسه هل ال PGD safe على ال embryo أم بيعمل
+
+453
+00:31:14,330 --> 00:31:17,650
+defect لل embryo؟ والله معظم .. معظم المقالات اللي
+
+454
+00:31:17,650 --> 00:31:20,930
+قرأناها و معظم المراجع العلمية الحديثة والقديمة
+
+455
+00:31:20,930 --> 00:31:25,610
+تقول أن ال PGD يعتبرvery safe عن ال embryo لأن ال
+
+456
+00:31:25,610 --> 00:31:29,170
+embryo زي ما حكينا يستطيع ان يتأقلم على الوضع
+
+457
+00:31:29,170 --> 00:31:33,410
+الجديد بسرعة وتستمر عملية النمو المتعلقة فيه
+
+458
+00:31:33,410 --> 00:31:38,570
+فبالتالي ال BGD safe بشكل كبير جدا evaluation of
+
+459
+00:31:38,570 --> 00:31:41,570
+children born after BGD does not show any
+
+460
+00:31:41,570 --> 00:31:48,230
+indication for a determinal effect of the process
+
+461
+00:31:48,230 --> 00:31:51,190
+of new growth or neurological development والدليل
+
+462
+00:31:51,190 --> 00:31:57,380
+ان دراسةدراسة عملت scanning على ال embryo أو على
+
+463
+00:31:57,380 --> 00:32:01,680
+الأطفال اللي أجوا من embryo اتعرض لل PGD فوجدوا
+
+464
+00:32:01,680 --> 00:32:05,800
+أنه ما عندهم أي مشكلة في عملية النمو ما عندهم أي
+
+465
+00:32:05,800 --> 00:32:11,540
+مشكلة في أيضا المشاكل اللي لها علاقة بالأعصاب و
+
+466
+00:32:11,540 --> 00:32:15,220
+التي تعمل على إيقاف ال development فبالتالي أنجبت
+
+467
+00:32:15,220 --> 00:32:20,960
+الأطفال التي أتت من أجنة خضعت لل PGD بشكل طبيعي من
+
+468
+00:32:20,960 --> 00:32:23,940
+حيث النمومن حيث الـ Intelligence من حيث الـ
+
+469
+00:32:23,940 --> 00:32:26,680
+Nervous System من حيث الـ Reaction و الـ Action
+
+470
+00:32:26,680 --> 00:32:31,420
+مافيش أي مشكلة سؤال تاني هل الـ PGD يُعتبر ضامن
+
+471
+00:32:31,420 --> 00:32:34,580
+إنه تنجح عملية الـ IVF أو الإجزة يعطيني Healthy
+
+472
+00:32:34,580 --> 00:32:38,460
+Baby بنسبة 100%؟ طبعا للأسف هذه العملية مافيها
+
+473
+00:32:38,460 --> 00:32:43,580
+ضمان So there is no guarantee for PGD to giving a
+
+474
+00:32:43,580 --> 00:32:47,380
+completely healthy baby بنسبة 100% لأنك أنت بتدور
+
+475
+00:32:47,380 --> 00:32:50,640
+على جينات معينة موجودة في العائلة ممكن يصير لحظة
+
+476
+00:32:50,640 --> 00:32:54,910
+من لحظات ال mutationيعطيك طفرة تعطيك مرض جديد وارد
+
+477
+00:32:54,910 --> 00:32:59,110
+أو يصير الحملية تتخلص بسبب external factor ل
+
+478
+00:32:59,110 --> 00:33:03,030
+الجنين فيصير اندي a portion وارد فبالتالي مافي
+
+479
+00:33:03,030 --> 00:33:07,290
+حاجة اسمها guarantee بنسبة 100% so no there is
+
+480
+00:33:07,290 --> 00:33:09,910
+many different factors can be affected in the
+
+481
+00:33:09,910 --> 00:33:14,650
+chance of IVF successful or success transferring
+
+482
+00:33:14,650 --> 00:33:18,190
+an embryo that have undergone PGD does not
+
+483
+00:33:18,190 --> 00:33:22,350
+guarantee a pregnancy or a healthy baby حوالي3 إلى
+
+484
+00:33:22,350 --> 00:33:27,510
+5% كل pregnancy كل حالة حمل في عندها 3 إلى 5% as
+
+485
+00:33:27,510 --> 00:33:32,790
+risk for baby lose or defect يعني كل سيدة بتحمل
+
+486
+00:33:32,790 --> 00:33:37,730
+حمل معين عندها احتمالية فقدان الجنين بمعدل 3 إلى 5
+
+487
+00:33:37,730 --> 00:33:42,250
+% يعني بمعنى أخر عندي خمس سيدات بيصير عندهم حمل
+
+488
+00:33:42,250 --> 00:33:47,270
+ممكن يصير عندهم فقدان للجنين فقدان للجنين so what
+
+489
+00:33:47,270 --> 00:33:50,680
+is the advantage of PGDالـ PGD له عدة advantages
+
+490
+00:33:50,680 --> 00:33:53,480
+إنه بعمل لـ improved للـ embryo selection لأن ما
+
+491
+00:33:53,480 --> 00:33:57,000
+برجع إلا للـ embryo اللي واثق إن هذا المرض الوراثي
+
+492
+00:33:57,000 --> 00:34:00,400
+مش موجود بناء على ال data الموجودة عليه بعمل
+
+493
+00:34:00,400 --> 00:34:06,080
+reduction أو decline لمعدل نقل الأجنة التي تحتوى
+
+494
+00:34:06,080 --> 00:34:10,040
+على تشوّق قبل ال implantation بعمل عملية reduction
+
+495
+00:34:10,040 --> 00:34:12,940
+for transfer of embryo that will lead to pregnancy
+
+496
+00:34:12,940 --> 00:34:17,700
+loss فبالتاليمعدل فقدان الجنين معدل ال up portion
+
+497
+00:34:17,700 --> 00:34:21,360
+معدل ال spontaneous up portion بقل لإن أنا برجع
+
+498
+00:34:21,360 --> 00:34:26,240
+الجنين السليم برجع الجنين الحيوي إلى حد ما reduce
+
+499
+00:34:26,240 --> 00:34:30,420
+the financial responsibility طبعا خد بالك أنه معنى
+
+500
+00:34:30,420 --> 00:34:34,640
+جنين فقد أو جنين تم إعادته وصار له up portion
+
+501
+00:34:34,640 --> 00:34:40,460
+معناه في مشاكل صحية مشاكل نفسية مشاكل آطفية عند ال
+
+502
+00:34:40,460 --> 00:34:46,770
+two couples معناه إعادة ال cycleيعني دفع و cost
+
+503
+00:34:46,770 --> 00:34:52,790
+أعلى فده أنا بتجنبها من خلال ال BGD ايضا ال BGD
+
+504
+00:34:52,790 --> 00:34:56,950
+بيعطي ضعم نفسي من ناحية إيجابية positive بشكل كبير
+
+505
+00:34:56,950 --> 00:35:02,430
+جدا مما يساعد على إكمال الحياة و إكمال عملية
+
+506
+00:35:02,430 --> 00:35:05,890
+الإنجاب بالشكل الطبيعي لما والله السيدة و ال two
+
+507
+00:35:05,890 --> 00:35:09,550
+couples بتعرف أنه الجنين اللي تم إرجاع هو الجنين
+
+508
+00:35:09,550 --> 00:35:14,040
+السليم طبعا بصير عنده نوع من أنواع الاهتمامبشكل
+
+509
+00:35:14,040 --> 00:35:19,560
+كبير جدا القلق بقل فبالتالي معدل فقدار الجنين من
+
+510
+00:35:19,560 --> 00:35:24,220
+خلال ال stress العالي بقل بشكل كبير جدا هذه فوائد
+
+511
+00:35:24,220 --> 00:35:29,060
+ال BGD خلصنا من فوائد ال BGD واتكلمنا عنها نيجي
+
+512
+00:35:29,060 --> 00:35:32,400
+لمرحلة تانية من مراحل ال genetic testing إلها
+
+513
+00:35:32,400 --> 00:35:35,100
+علاقة بال بي جي إلها علاقة أيضا بال sex selection
+
+514
+00:35:35,100 --> 00:35:38,520
+إلها علاقة بال embryo biopsyاسمها sex selection طب
+
+515
+00:35:38,520 --> 00:35:41,700
+شو علاقة ال embryo biopsy بال sex selection؟ لأن
+
+516
+00:35:41,700 --> 00:35:45,220
+ال sex selection هو عبارة عن فحص جيني يحتاج إلى ال
+
+517
+00:35:45,220 --> 00:35:48,840
+embryo biopsy لكي يتم لأن ال embryo biopsy هي خزعة
+
+518
+00:35:48,840 --> 00:35:52,980
+من الجنين تحتوي على مادة وراثية أقوم بفحصها من
+
+519
+00:35:52,980 --> 00:35:56,980
+خلال ال sex selection طبعا ال sex selection هو
+
+520
+00:35:56,980 --> 00:36:02,770
+مصطلح يستخدم بشكل عام as a medical termas medical
+
+521
+00:36:02,770 --> 00:36:08,110
+term إذا كان هدفه طبي ولكن أصبح استخداماته مختلفة
+
+522
+00:36:08,110 --> 00:36:12,190
+ال sex selection we can use to making selection of
+
+523
+00:36:12,190 --> 00:36:15,790
+the embryo for transfer and implantation followed
+
+524
+00:36:15,790 --> 00:36:21,490
+IVF separating sperm and selectivity transmitting
+
+525
+00:36:21,490 --> 00:36:26,890
+a pregnancy يعني sex selection بمعنى آخر هو مصطلح
+
+526
+00:36:26,890 --> 00:36:32,940
+يستخدم لاختيار جنس المولود أو عمليةتستخدم لاختيار
+
+527
+00:36:32,940 --> 00:36:36,780
+جنس المولود طبعا في الغالب هي عبارة عن عملية قطبية
+
+528
+00:36:36,780 --> 00:36:40,960
+خاصة في العوائل التي تحتوي على أمراض متعلقة
+
+529
+00:36:40,960 --> 00:36:45,860
+بالفيميل فبالتالي بيعطيني فيميل مشوهة أو فيميل
+
+530
+00:36:45,860 --> 00:36:51,640
+عندها مشاكل جينية أو فيميل defect فبالتالي مش منطق
+
+531
+00:36:51,640 --> 00:36:54,360
+اروح ارجع الأجنة اللي عندهم female او ال female
+
+532
+00:36:54,360 --> 00:36:58,200
+inferior طبعا ال six solution ممكن انا اعمله من
+
+533
+00:36:58,200 --> 00:37:02,220
+خلالتحديد جينات معينة إنها علاقة بالـ Male أو بالـ
+
+534
+00:37:02,220 --> 00:37:04,720
+Female، أي طريقة أو أعمل separation للـ
+
+535
+00:37:04,720 --> 00:37:08,380
+spermatozoa إن أحضن الـ boy ده فقط بـ sperm يحمل Y
+
+536
+00:37:08,380 --> 00:37:12,460
+كروموزوم أو يحمل X كروموزوم بناء على شو الهدف من
+
+537
+00:37:12,460 --> 00:37:15,740
+ال sex selection أو بعمل حاجة بنسميها للأسف
+
+538
+00:37:15,740 --> 00:37:19,920
+بيسخدموها بشكل أو بآخر إنه selectivity pregnancy
+
+539
+00:37:19,920 --> 00:37:24,100
+أو بمعنى آخر cancelling pregnancy يعني بعد الشهر
+
+540
+00:37:24,100 --> 00:37:29,160
+التاني أو التالت أو الرابع اتأكد إنه المولودmale
+
+541
+00:37:29,160 --> 00:37:33,960
+فأجهضه اتأكد ان المولود female فأجهضها هذه تعتبر
+
+542
+00:37:33,960 --> 00:37:37,240
+طريقة من طرق ال sex selection التي كانت تستخدم
+
+543
+00:37:37,240 --> 00:37:42,580
+فيما سبق بكميات كبيرة جدا طبعا بالنسبة لل sex
+
+544
+00:37:42,580 --> 00:37:47,020
+selection has a wide range of ethical legal social
+
+545
+00:37:47,020 --> 00:37:51,440
+problem يعني ماذا ده حتى لأنه رغم انه عمر طبي الا
+
+546
+00:37:51,440 --> 00:37:55,350
+انه في بعض المشاكلالأخلاقية عليه، بعض المشاكل
+
+547
+00:37:55,350 --> 00:37:58,270
+الطبية عليه، بعض المشاكل اجتماعية عليه في بعض
+
+548
+00:37:58,270 --> 00:38:03,890
+المجتمعات ما بتقبل ان يحصل sex selection في دولتها
+
+549
+00:38:03,890 --> 00:38:07,490
+أو في مجتمعها في بعض الدول عليها فرض انه ما تعمل
+
+550
+00:38:07,490 --> 00:38:10,930
+sex selection بعد الحرب العالمية تانية تتانية انه
+
+551
+00:38:10,930 --> 00:38:14,770
+ممنوع انت كدولة تعملي genetic implantation ممنوع
+
+552
+00:38:14,770 --> 00:38:19,950
+كدولة تعملي sex selection إليها هذا من أحد الفروضة
+
+553
+00:38:19,950 --> 00:38:24,700
+اللتي فرضت عليهاطبعا الـ Gender Selection is used
+
+554
+00:38:24,700 --> 00:38:28,500
+to prevent genetic disease the process is called
+
+555
+00:38:28,500 --> 00:38:31,880
+medical genetic أو gender selection إذا كان الهدف
+
+556
+00:38:31,880 --> 00:38:36,800
+الأساسي من اختيار جنس مولود تجنب مرض ورث معين فعند
+
+557
+00:38:36,800 --> 00:38:40,940
+الإذن بسميه medical gender selection أو medical
+
+558
+00:38:40,940 --> 00:38:45,380
+sex selection وهذا الهدف الأساسي من هذه العملية من
+
+559
+00:38:45,380 --> 00:38:48,520
+أشهر الأمراض هي الأمراض المتعلقة بال sex link
+
+560
+00:38:48,520 --> 00:38:53,860
+disorder أو ال X linkdisorder التي تخصيب الذكور عن
+
+561
+00:38:53,860 --> 00:38:58,340
+الاناث بكمية كبيرة جدا بعض الأحيان يكون الهدف من
+
+562
+00:38:58,340 --> 00:39:01,300
+ال sex selection ليس طبي فبسميه في هذه الحالة
+
+563
+00:39:01,300 --> 00:39:05,540
+elective اختياري انه انا والله بدي موليد بدي عيلة
+
+564
+00:39:05,540 --> 00:39:08,600
+تكونها اناث او بدي عيلة تكونها ذكور او بدي balance
+
+565
+00:39:08,600 --> 00:39:12,220
+اتنين الاناس اتنين الذكور فادم يسميه elective sex
+
+566
+00:39:12,220 --> 00:39:17,460
+selection او non medical sex selection ايضا زي ما
+
+567
+00:39:17,460 --> 00:39:22,340
+حكينا انه اكثرالأسباب التي تؤدي لعمل sex relation
+
+568
+00:39:22,340 --> 00:39:26,240
+هي ال family balancing أنه أنا بدي عيلة فقط قفلين
+
+569
+00:39:26,240 --> 00:39:31,000
+ولد و بنت بدي عيلة خمسة ولدين و تلت بنات و تلت
+
+570
+00:39:31,000 --> 00:39:33,740
+بنات وولدين وها كذا يعني بدي نوع من أنواع
+
+571
+00:39:33,740 --> 00:39:38,940
+الإختيارية أو نوع من أنواع الإتزال في أفراد الأسرة
+
+572
+00:39:38,940 --> 00:39:43,320
+طبعا هذا الأمر منطقيا غير مقبولطب كيف بدنا نعمل
+
+573
+00:39:43,320 --> 00:39:45,300
+six selection؟ و إيش طبيعة العين اللى بدنا
+
+574
+00:39:45,300 --> 00:39:48,460
+نستخدمها؟ في مسابق كانوا يستخدموا حاجة بتسميها
+
+575
+00:39:48,460 --> 00:39:51,620
+chronic villus sampling شو يعني chronic villus
+
+576
+00:39:51,620 --> 00:39:56,780
+sampling؟ CVS chronic villus sampling ببساطة جدا
+
+577
+00:39:56,780 --> 00:40:00,700
+is a paternal test in which sample of chronic
+
+578
+00:40:00,700 --> 00:40:04,260
+villi is removed from the placenta of testing يعني
+
+579
+00:40:04,260 --> 00:40:10,090
+أنا كطبيب بروح باخد جزء أو .. يا إماخلايا من خلايا
+
+580
+00:40:10,090 --> 00:40:14,530
+البلاسينتا أو دم من دم لبلاسينتا وبعمله عملية
+
+581
+00:40:14,530 --> 00:40:18,850
+فحوصات لتبحث عن الجينات المتعلقة بال female أو
+
+582
+00:40:18,850 --> 00:40:22,730
+الجينات المتعلقة بال male بشكل أساسي that test can
+
+583
+00:40:22,730 --> 00:40:27,390
+be done as early as 10 weeks of pregnancy يعني هذا
+
+584
+00:40:27,390 --> 00:40:31,130
+الفحص أو هذا ال sample اللي سميتها chronic villus
+
+585
+00:40:31,130 --> 00:40:35,830
+sampling بتخضع لها المرأة في أول عشر أسابيع من
+
+586
+00:40:35,830 --> 00:40:39,990
+عملية الحببطبعا chronic villasamling كان exhibited
+
+587
+00:40:39,990 --> 00:40:42,970
+if a baby has chromosomal conditions such as down
+
+588
+00:40:42,970 --> 00:40:46,230
+syndrome and other type of genetic disorder like
+
+589
+00:40:46,230 --> 00:40:49,810
+cystic fibrosis also chronic villasamling can
+
+590
+00:40:49,810 --> 00:40:54,270
+provide viable information about your baby healthy
+
+591
+00:40:54,270 --> 00:40:58,590
+يعني أنا لما أخد عين الدم أو عين نسيجية من ال
+
+592
+00:40:58,590 --> 00:41:02,230
+placenta تحت مصطلح ال chronic villasamling أنا
+
+593
+00:41:02,230 --> 00:41:06,890
+باخد معلومات طبية عن حالة المولودممكن أشخص جنس
+
+594
+00:41:06,890 --> 00:41:10,570
+المولود منها ممكن أعرف هل المولود يحتوي على بعض
+
+595
+00:41:10,570 --> 00:41:13,470
+الأمراض الوراثية الـGastric Fibrosis for example
+
+596
+00:41:13,470 --> 00:41:18,170
+أو الـ Down Syndrome النوع التاني من أنواع الـ
+
+597
+00:41:18,170 --> 00:41:20,930
+material التي يمكن أن تُستخدم في حالة الـ sex
+
+598
+00:41:20,930 --> 00:41:25,470
+selection الأمنو- الامنوسينتيسيز وهي عبارة عن أخذ
+
+599
+00:41:25,470 --> 00:41:29,190
+عينة من السائل المحيط بالجنين السائل المحيط
+
+600
+00:41:29,190 --> 00:41:33,810
+بالجنين هو عبارة عن سائل مغذر الجنين، حامل الجنين
+
+601
+00:41:33,990 --> 00:41:37,390
+يحتوي على بعض الخلايا المتعلقة بالجنين فلو أنا
+
+602
+00:41:37,390 --> 00:41:41,930
+أخدت sample منها أنا كده أخدت cells related with
+
+603
+00:41:41,930 --> 00:41:45,690
+embryo يعني أنا كده أخدت مادة ورثية لها علاقة
+
+604
+00:41:45,690 --> 00:41:50,090
+بالجنين لها علاقة بالجنين what is the purpose of
+
+605
+00:41:50,090 --> 00:41:52,830
+the aminothensis? check the inherited blood
+
+606
+00:41:52,830 --> 00:41:54,870
+disorder like sickle cell anemia, hemophilia,
+
+607
+00:41:54,950 --> 00:41:59,210
+thalassemia muscular skeletal disorder check
+
+608
+00:41:59,210 --> 00:42:02,350
+chromosome abnormality and fetal infection and
+
+609
+00:42:02,350 --> 00:42:06,580
+also we can use itfor sex selection or sex
+
+610
+00:42:06,580 --> 00:42:10,820
+determination هذه أهم الصفات أو أهم الاستخدامات
+
+611
+00:42:10,820 --> 00:42:18,100
+التي تنطوي أو تتعلق باخذ عينة من السائل الجنين
+
+612
+00:42:18,100 --> 00:42:21,360
+خلينا نشوف الفيديو اللي بتكلم عن هذا الموضوع وكيف
+
+613
+00:42:21,360 --> 00:42:25,420
+بياخد العينة المتعلقة بالسائل الجنين
+
+614
+00:42:29,970 --> 00:42:33,750
+Amniocentesis Amniocentesis is a medical procedure
+
+615
+00:42:33,750 --> 00:42:37,810
+called in prenatal diagnosis of chromosomal
+
+616
+00:42:37,810 --> 00:42:43,560
+abnormalities and fetal infectionsوهي أيضًا
+
+617
+00:42:43,560 --> 00:42:46,220
+استخدامة لتحريك الزبدة في الواقع التي تحتوي عدد
+
+618
+00:42:46,220 --> 00:42:49,620
+صغير من الموارد الأمنياطية التي تحتوي على دماغ
+
+619
+00:42:49,620 --> 00:42:54,340
+أمنياطية مجموعة أمنياطية مجموعة أمنياطية مجموعة
+
+620
+00:42:54,340 --> 00:42:54,580
+أمنياطية مجموعة أمنياطية مجموعة أمنياطية مجموعة
+
+621
+00:42:54,580 --> 00:42:55,180
+أمنياطية مجموعة أمنياطية مجموعة أمنياطية مجموعة
+
+622
+00:42:55,180 --> 00:42:58,940
+أمنياطية مجموعة أمنياطية مجموعة أمنياطية مجموعة
+
+623
+00:42:58,940 --> 00:43:05,000
+أمنياطية مجموعة أمنياطية مجموعة أمنياطية مجموعة
+
+624
+00:43:05,000 --> 00:43:11,480
+أمنياطية مجموعة أمنياطية مجمو
+
+625
+00:43:39,160 --> 00:43:42,660
+ببساطة، حكى عن الـ Amniotic Fluid والسائل المحيط
+
+626
+00:43:42,660 --> 00:43:45,830
+بالجنينوسائل يحتوي على العديد من البروتينات
+
+627
+00:43:45,830 --> 00:43:48,930
+والإنزيمات المتعلقة بالجنين بالإضافة إلى بعض
+
+628
+00:43:48,930 --> 00:43:52,590
+الخلايا الجدية المتعلقة بالجنين التي يمكن فصلها
+
+629
+00:43:52,590 --> 00:43:56,430
+وعمل culture لها لكي نحصل علامات دوراتية كافية
+
+630
+00:43:56,430 --> 00:44:01,170
+لإجراء الفحوصات الطبية والفحوصات الجينية المطلوبة
+
+631
+00:44:01,170 --> 00:44:06,090
+هذا بالنسبة للـ Amnotic Fluid أو عملية الـ
+
+632
+00:44:06,090 --> 00:44:12,720
+Amnothynthesisالتي يمكن من خلالها سحب جزء من الـ
+
+633
+00:44:12,720 --> 00:44:16,480
+Amniotic Fluid لإجراء الحصافة الطبية المطلوبة
+
+634
+00:44:16,480 --> 00:44:19,800
+النوع التالت أو الطريقة التالتة من طرق عمل Sex
+
+635
+00:44:19,800 --> 00:44:22,880
+Selection وهي الـ Sperm Separation by
+
+636
+00:44:22,880 --> 00:44:27,500
+Fluocytometer أنه أنا قبل ما أعمل حقن مجهري بفصل
+
+637
+00:44:27,500 --> 00:44:31,820
+الـ spermatozoa إلى sperm تحمل Y-chromosome و
+
+638
+00:44:31,820 --> 00:44:36,380
+sperm يحمل X-chromosome وبناء على حاجة المريض بحقن
+
+639
+00:44:36,380 --> 00:44:40,800
+يا إما بالـ X-chromosomeSperm with X Chromosome أو
+
+640
+00:44:40,800 --> 00:44:44,740
+Sperm with Y Chromosome طب كيف انا بدي افصل ال X
+
+641
+00:44:44,740 --> 00:44:49,160
+عن ال Y Chromosome الموجودة في Sperm Metazoa ممكن
+
+642
+00:44:49,160 --> 00:44:54,140
+افصلها بناء على كثافة ال DNA او كمية ال DNA فوجدوا
+
+643
+00:44:54,140 --> 00:44:58,380
+ان ال Sperm Metazoa المحملة بال X Chromosome حوالي
+
+644
+00:44:58,380 --> 00:45:04,240
+2.8% more DNA than those carrying Y Chromosome
+
+645
+00:45:04,240 --> 00:45:07,700
+يعني بمعنى اخر ال Sperm Metazoaاللي إلها علاقة
+
+646
+00:45:07,700 --> 00:45:10,860
+بالـ X كرموزوم أو محمول عليها الـ X كرموزوم كمية
+
+647
+00:45:10,860 --> 00:45:13,960
+الـ DNA أكتر من الـ sperm المتزول عليها Y كرموزوم
+
+648
+00:45:13,960 --> 00:45:17,440
+بمعدل 2.8 والسبب زي أحنا ما بنعرف في الـ
+
+649
+00:45:17,440 --> 00:45:22,200
+karyotyping أن الـ Y كرموزوم أقصر من الـ X كرموزوم
+
+650
+00:45:22,200 --> 00:45:26,700
+الـ X كرموزوم very long مقارنة بالـ Y كرموزوم
+
+651
+00:45:26,700 --> 00:45:30,460
+فبالتالي وجدوا أن كمية الـ DNA في الـ X أكتر من
+
+652
+00:45:30,460 --> 00:45:34,160
+كمية الـ DNA في الـ Y أو الـ sperm المحمل عليه الـ
+
+653
+00:45:34,160 --> 00:45:41,360
+Y كرموزوم بمعدل2.8 فممكن ببساطة جدا باستخدام ال
+
+654
+00:45:41,360 --> 00:45:45,500
+fluorocytometer أستخدم صبغة هذه الصبغة related
+
+655
+00:45:45,500 --> 00:45:49,720
+with amount of DNA فهي ترتبط بكمية ال DNA الموجودة
+
+656
+00:45:49,720 --> 00:45:53,580
+هنا وكمية ال DNA الموجودة هنا طالما ال X sperm
+
+657
+00:45:53,580 --> 00:45:57,660
+يحتوي على كمية DNA أكبر فبالتالي كمية صبغة أكبر
+
+658
+00:45:57,660 --> 00:46:01,360
+هترتبط فيها طالما ال Y sperm يحتوي على كمية DNA
+
+659
+00:46:01,360 --> 00:46:08,460
+أقل هترتبط في كميةدى يعني صبغة أقل فبيجي بعد كده
+
+660
+00:46:08,460 --> 00:46:15,140
+بيجي بقطع بعمل عملية ادخال لل Siemens sample في
+
+661
+00:46:15,140 --> 00:46:18,680
+capillary tube هذه ال capillary tube تمشي من خلال
+
+662
+00:46:18,680 --> 00:46:24,120
+مثلا طيار الكهربائي و في أخرها laser line بقطع ال
+
+663
+00:46:24,120 --> 00:46:27,400
+spermatozoa و بيقيز جداش كمية الصبغة و بين أعلى
+
+664
+00:46:27,400 --> 00:46:31,760
+قيمة الصبغة مقارنة مع reference value موجودةبقسم
+
+665
+00:46:31,760 --> 00:46:36,500
+هذا X-Sperm وهذا Y-Sperm وبفصلهم إلى two separated
+
+666
+00:46:36,500 --> 00:46:40,680
+tubes بعد كده أنا واجه ما بدي أو زي ما بدي أو بناء
+
+667
+00:46:40,680 --> 00:46:43,400
+على احتياج المريض يا اما بحتنها بال spermatozoa
+
+668
+00:46:43,400 --> 00:46:46,620
+الموجودة في ال tube اللي تتحتوي على X-Sperm أو ال
+
+669
+00:46:46,620 --> 00:46:49,600
+spermatozoa الموجودة في ال tube اللي تحتوي على Y
+
+670
+00:46:49,600 --> 00:46:54,800
+-Sperm فهذه بنسميها sperm separation by flow
+
+671
+00:46:54,800 --> 00:46:58,640
+cytometer وهي عبارة عن عملية تحدث قبل عملية ال
+
+672
+00:46:58,640 --> 00:47:01,820
+fertilization قبل عملية ال fertilizationفي طريقة
+
+673
+00:47:01,820 --> 00:47:05,960
+تانية و طريقة ماشي طريقة ولكن مشكلة في كتير لغة
+
+674
+00:47:05,960 --> 00:47:10,340
+حواليها اسمها طريقة .. طريقة اسمها Ericsson
+
+675
+00:47:10,340 --> 00:47:13,180
+albumin method طبعا اللغة اللي صار حواليها لأن
+
+676
+00:47:13,180 --> 00:47:16,460
+معظم المقالات اللي نشرت كان Ericsson موجود فيها
+
+677
+00:47:16,460 --> 00:47:20,860
+يعني معظم المقالات اللي لها علاقة بفصل spermatozoa
+
+678
+00:47:20,860 --> 00:47:24,340
+بناء على طريقة Ericsson albumin method كان
+
+679
+00:47:24,340 --> 00:47:30,480
+Ericsson هو الكاتب و المؤلف الموجود في كل المقالات
+
+680
+00:47:31,050 --> 00:47:34,150
+طبعا الـ effectiveness of this method is high
+
+681
+00:47:34,150 --> 00:47:40,070
+..highly disputed يعني في عندها شكوك حواليها، في
+
+682
+00:47:40,070 --> 00:47:43,390
+لغب حواليها، في كلام عنها الريكسون method involve
+
+683
+00:47:43,390 --> 00:47:46,590
+placing special washing sperm cell on the top of
+
+684
+00:47:46,590 --> 00:47:49,910
+layer solution of albumin ببساطة جدا بجيب solution
+
+685
+00:47:49,910 --> 00:47:52,910
+of albumin و بجيب عينة ال spermatozoa بعد ال
+
+686
+00:47:52,910 --> 00:47:56,810
+washing و بعد density gradient و بعد ال swamp up
+
+687
+00:47:56,810 --> 00:48:01,010
+بحملها فوق ال solution هذاطبعا معروف أن الـ
+
+688
+00:48:01,010 --> 00:48:06,350
+thickness للألبومين مختلفة عن ال thickness للمادة
+
+689
+00:48:06,350 --> 00:48:10,630
+أو ال media اللي عملت فيها washing لل spermatozoa
+
+690
+00:48:10,630 --> 00:48:13,890
+فبالتالي ال spermatozoa بتبدأ أنها تتحرك نحو
+
+691
+00:48:13,890 --> 00:48:17,890
+الأسفل بفعلة جاذبية و المعروف كل ما اتحركنا للأسفل
+
+692
+00:48:17,890 --> 00:48:20,570
+ال thickness أو ال density تبعة ال albumin
+
+693
+00:48:20,570 --> 00:48:24,470
+solution هتكون أعلى albumin is kind of a protein
+
+694
+00:48:24,470 --> 00:48:29,060
+found in the cementThe albumin is layer with
+
+695
+00:48:29,060 --> 00:48:32,160
+increased thickness with the thickness layer in
+
+696
+00:48:32,160 --> 00:48:35,780
+the bottom معناه أنه كل ما توجهنا للأسفل هيكون ال
+
+697
+00:48:35,780 --> 00:48:38,220
+thickness أو ال density خلّيني أقول ال thickness
+
+698
+00:48:38,220 --> 00:48:41,440
+زي ما موجودة في ال slide هتكون أعلى فبالتالي هلاقي
+
+699
+00:48:41,440 --> 00:48:45,320
+ال spermatozoon هتتقاوم .. هيتلاقي مقاومة كبيرة
+
+700
+00:48:45,320 --> 00:48:50,440
+جدا أثناء عملية انتقالها من السطح لل albumin
+
+701
+00:48:50,440 --> 00:48:55,040
+solution حتى أسفل اللمبوبة الفكرة أن ال Y sperm
+
+702
+00:48:55,040 --> 00:48:59,030
+cell والسوامdown and arrive to the thick layer
+
+703
+00:48:59,030 --> 00:49:02,550
+faster ليه؟ لأن كمية الـ DNA الموجودة فيه كمية
+
+704
+00:49:02,550 --> 00:49:08,710
+قليلة جدا مقارنة بالـ X-Spermatozoa for those that
+
+705
+00:49:08,710 --> 00:49:12,310
+want a baby the filtration method is called by
+
+706
+00:49:12,310 --> 00:49:17,570
+insemination or IY طالما أنا بدي baby male هحقن
+
+707
+00:49:17,570 --> 00:49:21,230
+البوايضة من الـ spermatozoa الموجودة في منطقة ال
+
+708
+00:49:21,230 --> 00:49:25,350
+thicker solution layerوالله إذا بدي على سبيل
+
+709
+00:49:25,350 --> 00:49:29,430
+المثال female as imperial بحقنها من ال spermatozoa
+
+710
+00:49:29,430 --> 00:49:34,910
+اللي موجودة في المنطقة العلوية لإنها بتكون كثافتها
+
+711
+00:49:34,910 --> 00:49:40,050
+او كثافة ال spermatozoa أعلى لإنه Y .. او لإنه X
+
+712
+00:49:40,050 --> 00:49:43,130
+spermatozoa spermatozoa يحتوى على ال X chromosome
+
+713
+00:49:43,130 --> 00:49:47,830
+اللي فيه مادة وراثية أعلى نحيثه الكميةفي بعض
+
+714
+00:49:47,830 --> 00:49:52,550
+الأحيان بيقولك لأ أنا عندي spermatozoa كتيرة بيدور
+
+715
+00:49:52,550 --> 00:49:56,330
+على جينات معينة بيدور على جينات معينة gene that
+
+716
+00:49:56,330 --> 00:50:02,010
+are exclusive of Y-chromosome خلصت من عملية sex
+
+717
+00:50:02,010 --> 00:50:06,610
+selection سواء كان pre-implantation أو بعد ال
+
+718
+00:50:06,610 --> 00:50:11,210
+pregnancy أو قبل عملية ال fertilization باستخدام
+
+719
+00:50:11,210 --> 00:50:15,740
+ال Eryxolipamine method لأ أنا عندي سارجانينأو
+
+720
+00:50:15,740 --> 00:50:18,960
+عندى أجنة فى المختبر حقنت وبدى أرجع بس الجنين اللى
+
+721
+00:50:18,960 --> 00:50:21,080
+هو عبارة عن الـ Male أو الجنين اللى عبارة عن
+
+722
+00:50:21,080 --> 00:50:24,060
+Female إذا بدى أرجع الجنين اللى عبارة عن ال Male
+
+723
+00:50:24,060 --> 00:50:28,580
+بدى أحاول باستخدام ال Fish Technique أبحث عن جينات
+
+724
+00:50:28,580 --> 00:50:32,480
+لا توجد إلا على ال Y-Chromosome فبالتالي ببحث عن
+
+725
+00:50:32,480 --> 00:50:36,460
+جينات مهمة وهي اللى باللون الأزرق زى ال AZF
+
+726
+00:50:36,460 --> 00:50:40,400
+Azospermia Factor 1 في عند ال 6th determining
+
+727
+00:50:40,400 --> 00:50:45,280
+region Yوهي المسؤولة عن إنتاج الـ Phenotype الخاصة
+
+728
+00:50:45,280 --> 00:50:50,220
+بالميل في عند الـ TspY Testis Specific Protein Y
+
+729
+00:50:50,220 --> 00:50:55,500
+-Link في عندي كمان Basic Protein on Y-Chromosome
+
+730
+00:50:55,500 --> 00:51:02,040
+في عندي الـ Delete in Azospermia 1 وفي عند ال Y
+
+731
+00:51:02,040 --> 00:51:07,860
+-Link Protein Kinase هذه معظمها الجينات لا تتواجد
+
+732
+00:51:07,860 --> 00:51:11,200
+إلا على الـ Y-Chromosome ولكن أشهرها التلاتة اللي
+
+733
+00:51:11,200 --> 00:51:16,150
+باللونالأزرق و بالذات رقم 2 باللون الأزرق اللي
+
+734
+00:51:16,150 --> 00:51:23,410
+سمته SRY 6-Determining Region Y هذه أشهر أنواع
+
+735
+00:51:23,410 --> 00:51:26,710
+الجينات المحملة على Y كرموزوم و التي من خلالها
+
+736
+00:51:26,710 --> 00:51:32,150
+أستطيع تحديد جنس المولود أو تحديد جنس الجنين
+
+737
+00:51:32,150 --> 00:51:37,450
+الموجود في البيتردش قبل عملية الرجعة عشان كده حكيت
+
+738
+00:51:37,450 --> 00:51:42,400
+أن ال embryo بيبسي ممكن أعملها بعد كده PCRأو fish
+
+739
+00:51:42,400 --> 00:51:45,840
+technique و هذه الطريقة طريقة تحديد الجينات يمكن
+
+740
+00:51:45,840 --> 00:51:50,420
+استخدام ال fish technique فيها بشكل سريع طبعا عند
+
+741
+00:51:50,420 --> 00:51:54,420
+slide بعد ال fish technique و عملت six
+
+742
+00:51:54,420 --> 00:51:58,020
+determination لجيت فيها اندي two spots لونها blue
+
+743
+00:51:58,020 --> 00:52:01,900
+و one spot green و one spot violet ال pam fetish
+
+744
+00:52:01,900 --> 00:52:05,520
+بتقول ايه؟ بتقول ايه هذه خلية تحتوي على خلية
+
+745
+00:52:05,520 --> 00:52:09,640
+مأخوذة من جنين يعني هذه ال plus two mirror عملنا
+
+746
+00:52:09,640 --> 00:52:13,560
+لها fish techniqueعطاني green color يعني هذا X
+
+747
+00:52:13,560 --> 00:52:19,340
+كرمزوم red color يعني Y كرمزوم وعندي blue color
+
+748
+00:52:19,340 --> 00:52:25,380
+علاقة بالكرمزوم رقم 18 كرمزوم 18 as we show normal
+
+749
+00:52:25,380 --> 00:52:29,820
+يعني عندي two copy يعني هذا الكرمزوم ماعندهش انبلو
+
+750
+00:52:29,820 --> 00:52:33,820
+دي من كرمزوم 18 ممكن أستخدم الكرمزوم 21؟ okay ممكن
+
+751
+00:52:33,820 --> 00:52:39,010
+بس بدي sequence related with كرمزوم 21فهذا بقدر
+
+752
+00:52:39,010 --> 00:52:44,750
+أقول إنه male with normal number of chromosome 18
+
+753
+00:52:44,750 --> 00:52:48,110
+يعني مافي عندي مشكلة في ال chromosome 18 لأنه two
+
+754
+00:52:48,110 --> 00:52:51,450
+copy طب ليش male لأنه في عندي ال red color و هو
+
+755
+00:52:51,450 --> 00:52:54,930
+عبارة عن ال probe موجهة ضد sequence لأ تواجد إلا
+
+756
+00:52:54,930 --> 00:52:58,930
+على ال Y-chromosome كده أنا بكون حدد الجنس المولود
+
+757
+00:52:58,930 --> 00:53:02,190
+بالإضافة إلى شخصتي المولود من حيث Down Syndrome
+
+758
+00:53:02,190 --> 00:53:05,730
+اللي له علاقة بال three copy من ال chromosome 18
+
+759
+00:53:05,730 --> 00:53:08,750
+موجودة ولا لأ؟فهذا normal لأنه عندي two copies من
+
+760
+00:53:08,750 --> 00:53:12,790
+كرموزوم 18 عندي X كرموزوم و عندي Y كرموزوم طبعا
+
+761
+00:53:12,790 --> 00:53:15,690
+هذه الطريقة بتسميها Fish technique fluorescent in
+
+762
+00:53:15,690 --> 00:53:19,650
+situ hybridization technique بهذا القدر نقوم قد
+
+763
+00:53:19,650 --> 00:53:22,690
+انتهينا من ال chapter 6 على أمل أن نلتقي في ال
+
+764
+00:53:22,690 --> 00:53:26,230
+chapter السابع و الأخير ان شاء الله في المحاضرات
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/0RZGsRZ35mw_raw.json b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/0RZGsRZ35mw_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..ce889b9fac932ce8c635c05d6f690e37d762b8e8
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/0RZGsRZ35mw_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 4793, "start": 20.69, "end": 47.93, "text": "أهلا و مرحبا اليوم إن شاء الله سوف نكمل تحقيق القرارات و سنركز على القرارات المزدوجة باستخدام القرارات المختلفة ربما القرارات التجاربية أو الفيزيوكالية مع قرارات المجتمع و سنرى تحقيق هذه القرارات و بعد ذلك سنذهب لقرارات ال MIS", "tokens": [10721, 3224, 15040, 4032, 3714, 2288, 5016, 3555, 995, 45595, 20498, 36145, 13412, 16606, 21984, 8608, 38688, 8717, 24793, 1211, 6055, 5016, 38436, 4587, 25062, 2288, 9640, 9307, 4032, 8608, 1863, 31747, 11622, 15844, 25062, 2288, 9640, 9307, 9673, 11622, 3215, 29245, 3660, 4724, 995, 14851, 9778, 3215, 10943, 25062, 2288, 9640, 9307, 9673, 46456, 46538, 3660, 12602, 3555, 15042, 25062, 2288, 9640, 9307, 16712, 7435, 9640, 3555, 10632, 34051, 27188, 1829, 11622, 1829, 2407, 4117, 6027, 10632, 20449, 12174, 2288, 9640, 9307, 9673, 7435, 39237, 3615, 4032, 8608, 1863, 2288, 7578, 6055, 5016, 38436, 4587, 29538, 25062, 2288, 9640, 9307, 4032, 39182, 29910, 23275, 8608, 1863, 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ال mixed policies على هذه الأربع متغيرات اختارولنا سياستين انتوا اختاروا سياستين نستخدمهم مع بعض ونشوف تأثيرهم expansion fiscal with", "tokens": [39237, 10943, 22807, 4724, 16254, 5551, 8592, 38688, 13412, 2407, 2423, 5065, 15844, 2423, 7467, 7657, 15844, 29538, 16247, 25513, 3615, 44650, 17082, 13546, 9307, 1975, 46456, 9640, 12610, 8315, 8608, 25528, 14851, 9957, 16472, 2655, 14407, 1975, 46456, 9640, 14407, 8608, 25528, 14851, 9957, 8717, 14851, 9778, 40448, 16095, 20449, 45030, 11242, 4032, 1863, 8592, 38688, 6055, 10721, 12984, 13546, 16095, 11260, 15897, 365], "avg_logprob": -0.21803976798599417, "compression_ratio": 1.4722222222222223, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 774.22, "end": 775.18, "word": "تمام؟", "probability": 0.6027628580729166}, {"start": 775.18, "end": 775.36, "word": " بدي", "probability": 0.41741943359375}, {"start": 775.36, "end": 775.6, "word": " أشوف", "probability": 0.88623046875}, {"start": 775.6, "end": 775.8, "word": " شو", 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expansionary fiscal with contractionary monetary وحللنا خلّيني ناخد expansionary fiscal with contractionary with expansionary monetary", "tokens": [9566, 3555, 45164, 12602, 2407, 33753, 3714, 47283, 3215, 7297, 300, 321, 366, 516, 281, 764, 364, 11260, 822, 15897, 3897, 365, 11260, 822, 26388, 3897, 37495, 22653, 16490, 1211, 11703, 9957, 1829, 8717, 5016, 4117, 1829, 8978, 11260, 822, 15897, 365, 11260, 822, 26388, 37495, 22653, 1975, 5016, 8315, 44713, 9778, 40448, 8315, 1975, 1829, 8592, 11260, 822, 15897, 365, 37372, 822, 26388, 4032, 5016, 1211, 1211, 8315, 16490, 1211, 11703, 9957, 1829, 8717, 47283, 3215, 11260, 822, 15897, 365, 37372, 822, 365, 11260, 822, 26388], "avg_logprob": -0.1711647700179707, "compression_ratio": 2.1390374331550803, "no_speech_prob": 0.0, "words": [{"start": 1236.63, "end": 1236.87, "word": "طب", "probability": 0.55157470703125}, {"start": 1236.87, "end": 1237.01, "word": " لو", "probability": 0.990234375}, {"start": 1237.01, "end": 1237.27, "word": " 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IS عبارة عن إيش؟ هو شكل بياني negative slope يعكس علاقة عكسية ما بين ال R و ال Y في سوق ال goods and services market صح؟ مظبوط ولا مش مظبوط؟ هيو increasing في ال R نزل ال Y", "tokens": [1863, 11622, 1211, 2655, 11933, 15730, 9154, 5016, 1863, 2423, 6205, 6225, 3555, 9640, 3660, 18871, 11933, 1829, 8592, 22807, 31439, 13412, 28820, 4724, 1829, 7649, 1829, 3671, 13525, 37495, 4117, 3794, 11203, 995, 28671, 6225, 4117, 3794, 10632, 19446, 49374, 2423, 497, 4032, 2423, 398, 8978, 8608, 30543, 2423, 10179, 293, 3328, 2142, 20328, 5016, 22807, 3714, 19913, 3555, 2407, 9566, 49429, 37893, 3714, 19913, 3555, 2407, 9566, 22807, 8032, 1829, 2407, 5662, 8978, 2423, 497, 8717, 11622, 1211, 2423, 398], "avg_logprob": -0.17460467513785305, "compression_ratio": 1.4393939393939394, "no_speech_prob": 0.0, "words": [{"start": 2150.14, "end": 2150.72, "word": "نزلت", "probability": 0.7652587890625}, {"start": 2150.72, "end": 2154.22, "word": " إذا", "probability": 0.6724853515625}, {"start": 2154.22, 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"probability": 0.405517578125}, {"start": 2410.11, "end": 2410.51, "word": " M", "probability": 0.93798828125}, {"start": 2410.51, "end": 2410.97, "word": " curve", "probability": 0.92431640625}], "temperature": 1.0}, {"id": 89, "seek": 244044, "start": 2413.49, "end": 2440.45, "text": "خد النقطة الأولى هيها عند ال interest rate this is E1 وهذا R1 Y1 شو اللي صار زيادة في ال Y؟ شو عملت في ال R؟ increased R so there is a positive relationship between Y and R this is E2 صح؟", "tokens": [9778, 3215, 28239, 47432, 3660, 16247, 12610, 7578, 39896, 11296, 43242, 2423, 1179, 3314, 341, 307, 462, 16, 37037, 15730, 497, 16, 398, 16, 13412, 2407, 13672, 1829, 20328, 9640, 30767, 1829, 18513, 3660, 8978, 2423, 398, 22807, 13412, 2407, 6225, 42213, 2655, 8978, 2423, 497, 22807, 6505, 497, 370, 456, 307, 257, 3353, 2480, 1296, 398, 293, 497, 341, 307, 462, 17, 20328, 5016, 22807], "avg_logprob": -0.253031717307532, "compression_ratio": 1.320855614973262, "no_speech_prob": 0.0, "words": [{"start": 2413.49, "end": 2413.75, "word": "خد", "probability": 0.72900390625}, {"start": 2413.75, "end": 2414.05, "word": " النقطة", "probability": 0.95703125}, {"start": 2414.05, "end": 2414.35, "word": " الأولى", "probability": 0.9423828125}, {"start": 2414.35, "end": 2414.91, "word": " هيها", "probability": 0.38836669921875}, {"start": 2414.91, "end": 2415.77, "word": " عند", "probability": 0.466064453125}, {"start": 2415.77, "end": 2415.91, "word": " ال", "probability": 0.955078125}, {"start": 2415.91, "end": 2416.21, "word": " interest", "probability": 0.677734375}, {"start": 2416.21, "end": 2416.49, "word": " rate", "probability": 0.97314453125}, {"start": 2416.49, "end": 2416.69, "word": " this", "probability": 0.331787109375}, {"start": 2416.69, "end": 2417.01, "word": " is", "probability": 0.9384765625}, {"start": 2417.01, "end": 2417.79, "word": " E1", "probability": 0.771484375}, {"start": 2417.79, "end": 2419.63, "word": " وهذا", "probability": 0.6572265625}, {"start": 2419.63, "end": 2420.29, "word": " R1", "probability": 0.78466796875}, {"start": 2420.29, "end": 2422.23, "word": " Y1", "probability": 0.6593017578125}, {"start": 2422.23, "end": 2423.69, "word": " شو", "probability": 0.747802734375}, {"start": 2423.69, "end": 2423.83, "word": " اللي", "probability": 0.955078125}, {"start": 2423.83, "end": 2424.03, "word": " صار", "probability": 0.98193359375}, {"start": 2424.03, "end": 2424.45, "word": " زيادة", "probability": 0.97998046875}, {"start": 2424.45, "end": 2424.59, "word": " في", "probability": 0.96533203125}, {"start": 2424.59, "end": 2424.71, "word": " ال", "probability": 0.77392578125}, {"start": 2424.71, "end": 2425.39, "word": " Y؟", "probability": 0.6240234375}, {"start": 2425.39, "end": 2425.51, "word": " شو", "probability": 0.91650390625}, {"start": 2425.51, "end": 2425.79, "word": " عملت", "probability": 0.95751953125}, {"start": 2425.79, "end": 2425.89, "word": " في", "probability": 0.95654296875}, {"start": 2425.89, "end": 2425.99, "word": " ال", "probability": 0.9697265625}, {"start": 2425.99, "end": 2428.29, "word": " R؟", "probability": 0.903564453125}, {"start": 2428.29, "end": 2430.97, "word": " increased", "probability": 0.403564453125}, {"start": 2430.97, "end": 2431.31, "word": " R", "probability": 0.9677734375}, {"start": 2431.31, "end": 2431.73, "word": " so", "probability": 0.1513671875}, {"start": 2431.73, "end": 2431.97, "word": " there", "probability": 0.9052734375}, {"start": 2431.97, "end": 2432.13, "word": " is", "probability": 0.95263671875}, {"start": 2432.13, "end": 2432.27, "word": " a", "probability": 0.798828125}, {"start": 2432.27, "end": 2432.61, "word": " positive", "probability": 0.93994140625}, {"start": 2432.61, "end": 2433.33, "word": " relationship", "probability": 0.91064453125}, {"start": 2433.33, "end": 2433.77, "word": " between", "probability": 0.94775390625}, {"start": 2433.77, "end": 2434.95, "word": " Y", "probability": 0.97998046875}, {"start": 2434.95, "end": 2435.35, "word": " and", "probability": 0.884765625}, {"start": 2435.35, "end": 2435.75, "word": " R", "probability": 0.9951171875}, {"start": 2435.75, "end": 2436.67, "word": " this", "probability": 0.72216796875}, {"start": 2436.67, "end": 2436.93, "word": " is", "probability": 0.9599609375}, {"start": 2436.93, "end": 2437.87, "word": " E2", "probability": 0.983154296875}, {"start": 2437.87, "end": 2440.45, "word": " صح؟", "probability": 0.8670247395833334}], "temperature": 1.0}, {"id": 90, "seek": 246091, "start": 2440.97, "end": 2460.91, "text": "إيه؟ ولا مش بظبط؟ So LM is a curve illustrates the positive relationship between Y and R and it illustrates also the different equilibrium points in the money market صح؟", "tokens": [28814, 1829, 3224, 22807, 49429, 37893, 4724, 19913, 3555, 9566, 22807, 407, 46529, 307, 257, 7605, 41718, 264, 3353, 2480, 1296, 398, 293, 497, 293, 309, 41718, 611, 264, 819, 15625, 2793, 294, 264, 1460, 2142, 20328, 5016, 22807], "avg_logprob": -0.2587890520691872, "compression_ratio": 1.2236842105263157, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 2440.97, "end": 2441.77, "word": "إيه؟", "probability": 0.674560546875}, {"start": 2441.77, "end": 2442.03, "word": " ولا", "probability": 0.58447265625}, {"start": 2442.03, "end": 2442.17, "word": " مش", "probability": 0.978515625}, {"start": 2442.17, "end": 2443.41, "word": " بظبط؟", "probability": 0.75625}, {"start": 2443.41, "end": 2443.59, "word": " So", "probability": 0.4091796875}, {"start": 2443.59, "end": 2444.75, "word": " LM", "probability": 0.3662109375}, {"start": 2444.75, "end": 2445.33, "word": " is", "probability": 0.939453125}, {"start": 2445.33, "end": 2447.23, "word": " a", "probability": 0.96728515625}, {"start": 2447.23, "end": 2447.71, "word": " curve", "probability": 0.966796875}, {"start": 2447.71, "end": 2449.11, "word": " illustrates", "probability": 0.68115234375}, {"start": 2449.11, "end": 2449.57, "word": " the", "probability": 0.87841796875}, {"start": 2449.57, "end": 2449.97, "word": " positive", "probability": 0.939453125}, {"start": 2449.97, "end": 2450.63, "word": " relationship", "probability": 0.91455078125}, {"start": 2450.63, "end": 2451.13, "word": " between", "probability": 0.935546875}, {"start": 2451.13, "end": 2451.69, "word": " Y", "probability": 0.8896484375}, {"start": 2451.69, "end": 2452.11, "word": " and", "probability": 0.9384765625}, {"start": 2452.11, "end": 2452.53, "word": " R", "probability": 0.99267578125}, {"start": 2452.53, "end": 2453.29, "word": " and", "probability": 0.70068359375}, {"start": 2453.29, "end": 2453.65, "word": " it", "probability": 0.935546875}, {"start": 2453.65, "end": 2454.29, "word": " illustrates", "probability": 0.9384765625}, {"start": 2454.29, "end": 2454.89, "word": " also", "probability": 0.86181640625}, {"start": 2454.89, "end": 2456.79, "word": " the", "probability": 0.900390625}, {"start": 2456.79, "end": 2457.37, "word": " different", "probability": 0.88818359375}, {"start": 2457.37, "end": 2458.01, "word": " equilibrium", "probability": 0.955078125}, {"start": 2458.01, "end": 2458.69, "word": " points", "probability": 0.90380859375}, {"start": 2458.69, "end": 2458.91, "word": " in", "probability": 0.9248046875}, {"start": 2458.91, "end": 2459.05, "word": " the", "probability": 0.88232421875}, {"start": 2459.05, "end": 2459.21, "word": " money", "probability": 0.9462890625}, {"start": 2459.21, "end": 2459.71, "word": " market", "probability": 0.93359375}, {"start": 2459.71, "end": 2460.91, "word": " صح؟", "probability": 0.8184407552083334}], "temperature": 1.0}, {"id": 91, "seek": 248742, "start": 2461.3, "end": 2487.42, "text": "يعكس توازنات في سوق النقد حُط قد أي نقطة نزل ال money demand و money demand 3 شو اللي بصير؟ هيلاجيله نقطة هنا هيك Y نزل و Y3 و R نزل to R3 so there is the same or they have the same direction positive relationship تمام افهمنا؟ ولا مافهمناش؟ تمام يعطيكم العفو", "tokens": [40228, 4117, 3794, 33427, 31377, 8315, 2655, 8978, 8608, 30543, 28239, 28543, 11331, 10859, 9566, 12174, 3215, 36632, 8717, 47432, 3660, 8717, 11622, 1211, 2423, 1460, 4733, 4032, 1460, 4733, 805, 13412, 2407, 13672, 1829, 4724, 9381, 13546, 22807, 39896, 15040, 7435, 26895, 3224, 8717, 47432, 3660, 34105, 39896, 4117, 398, 8717, 11622, 1211, 4032, 398, 18, 4032, 497, 8717, 11622, 1211, 281, 497, 18, 370, 456, 307, 264, 912, 420, 436, 362, 264, 912, 3513, 3353, 2480, 46811, 10943, 1975, 5172, 16095, 8315, 22807, 49429, 19446, 5172, 16095, 1863, 33599, 22807, 46811, 10943, 37495, 9566, 1829, 24793, 18863, 5172, 2407], "avg_logprob": -0.3092830873587552, "compression_ratio": 1.5523012552301256, "no_speech_prob": 1.7881393432617188e-07, "words": [{"start": 2461.3, "end": 2461.94, "word": "يعكس", "probability": 0.9013671875}, {"start": 2461.94, "end": 2462.94, "word": " توازنات", "probability": 0.92333984375}, {"start": 2462.94, "end": 2463.1, "word": " في", "probability": 0.93701171875}, {"start": 2463.1, "end": 2463.4, "word": " سوق", "probability": 0.94384765625}, {"start": 2463.4, "end": 2463.86, "word": " النقد", "probability": 0.963134765625}, {"start": 2463.86, "end": 2464.62, "word": " حُط", "probability": 0.3686930338541667}, {"start": 2464.62, "end": 2464.84, "word": " قد", "probability": 0.754150390625}, {"start": 2464.84, "end": 2465.02, "word": " أي", "probability": 0.77099609375}, {"start": 2465.02, "end": 2465.32, "word": " نقطة", "probability": 0.9806315104166666}, {"start": 2465.32, "end": 2465.82, "word": " نزل", "probability": 0.6783447265625}, {"start": 2465.82, "end": 2465.92, "word": " ال", "probability": 0.689453125}, {"start": 2465.92, "end": 2466.04, "word": " money", "probability": 0.7509765625}, {"start": 2466.04, "end": 2466.4, "word": " demand", "probability": 0.9375}, {"start": 2466.4, "end": 2466.6, "word": " و", "probability": 0.31298828125}, {"start": 2466.6, "end": 2466.76, "word": " money", "probability": 0.9033203125}, {"start": 2466.76, "end": 2467.18, "word": " demand", "probability": 0.9453125}, {"start": 2467.18, "end": 2467.54, "word": " 3", "probability": 0.4580078125}, {"start": 2467.54, "end": 2468.24, "word": " شو", "probability": 0.72802734375}, {"start": 2468.24, "end": 2468.32, "word": " اللي", "probability": 0.951171875}, {"start": 2468.32, "end": 2469.62, "word": " بصير؟", "probability": 0.709869384765625}, {"start": 2469.62, "end": 2470.24, "word": " هيلاجيله", "probability": 0.6280517578125}, {"start": 2470.24, "end": 2470.56, "word": " نقطة", "probability": 0.9607747395833334}, {"start": 2470.56, "end": 2470.76, "word": " هنا", "probability": 0.84423828125}, {"start": 2470.76, "end": 2471.74, "word": " هيك", "probability": 0.6925048828125}, {"start": 2471.74, "end": 2472.16, "word": " Y", "probability": 0.50830078125}, {"start": 2472.16, "end": 2472.66, "word": " نزل", "probability": 0.98779296875}, {"start": 2472.66, "end": 2473.08, "word": " و", "probability": 0.38525390625}, {"start": 2473.08, "end": 2473.52, "word": " Y3", "probability": 0.4920654296875}, {"start": 2473.52, "end": 2474.26, "word": " و", "probability": 0.96142578125}, {"start": 2474.26, "end": 2474.46, "word": " R", "probability": 0.71435546875}, {"start": 2474.46, "end": 2474.82, "word": " نزل", "probability": 0.9938151041666666}, {"start": 2474.82, "end": 2475.0, "word": " to", "probability": 0.1937255859375}, {"start": 2475.0, "end": 2475.48, "word": " R3", "probability": 0.92578125}, {"start": 2475.48, "end": 2476.06, "word": " so", "probability": 0.27099609375}, {"start": 2476.06, "end": 2476.28, "word": " there", "probability": 0.6396484375}, {"start": 2476.28, "end": 2476.58, "word": " is", "probability": 0.96728515625}, {"start": 2476.58, "end": 2477.26, "word": " the", "probability": 0.7041015625}, {"start": 2477.26, "end": 2477.58, "word": " same", "probability": 0.8974609375}, {"start": 2477.58, "end": 2477.86, "word": " or", "probability": 0.492431640625}, {"start": 2477.86, "end": 2478.18, "word": " they", "probability": 0.8642578125}, {"start": 2478.18, "end": 2478.62, "word": " have", "probability": 0.796875}, {"start": 2478.62, "end": 2478.8, "word": " the", "probability": 0.92578125}, {"start": 2478.8, "end": 2479.02, "word": " same", "probability": 0.90625}, {"start": 2479.02, "end": 2479.6, "word": " direction", "probability": 0.96533203125}, {"start": 2479.6, "end": 2480.18, "word": " positive", "probability": 0.81298828125}, {"start": 2480.18, "end": 2480.98, "word": " relationship", "probability": 0.91015625}, {"start": 2480.98, "end": 2482.02, "word": " تمام", "probability": 0.73193359375}, {"start": 2482.02, "end": 2483.56, "word": " افهمنا؟", "probability": 0.76787109375}, {"start": 2483.56, "end": 2483.96, "word": " ولا", "probability": 0.72998046875}, {"start": 2483.96, "end": 2485.8, "word": " مافهمناش؟", "probability": 0.808837890625}, {"start": 2485.8, "end": 2486.2, "word": " تمام", "probability": 0.811279296875}, {"start": 2486.2, "end": 2487.08, "word": " يعطيكم", "probability": 0.9107666015625}, {"start": 2487.08, "end": 2487.42, "word": " العفو", "probability": 0.79443359375}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2488.111, "duration_after_vad": 2296.7374999999906}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/1aY1T9K_Css_postprocess.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/1aY1T9K_Css_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..1ea8ac1071442195025ba50a69accfe1b4fdf4aa
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/1aY1T9K_Css_postprocess.srt
@@ -0,0 +1,2112 @@
+1
+00:00:21,050 --> 00:00:25,530
+اليوم ان شاء الله سنكمل الحلقة السادسة والتي هي
+
+2
+00:00:25,530 --> 00:00:31,130
+مصادر المال والمحافظة الوطنية في
+
+3
+00:00:31,130 --> 00:00:34,990
+السلاسة السابقة نتكلم عن بعض المصادر والمصادر
+
+4
+00:00:34,990 --> 00:00:38,010
+المالية
+
+5
+00:00:38,010 --> 00:00:44,540
+ومصادر المالالنظام الـ barter الذي تم إصلاحه
+
+6
+00:00:44,540 --> 00:00:57,800
+بإستعمال
+
+7
+00:00:57,800 --> 00:01:02,340
+نظام الـ barter نظام المقيدةوبعد ذلك، كانت فكرة
+
+8
+00:01:02,340 --> 00:01:08,920
+المال تم إصلاح المشكلات المختلفة التي تتعامل مع
+
+9
+00:01:08,920 --> 00:01:14,360
+نظام البرتقال اليوم، إن شاء الله، سنكمل مصطلح
+
+10
+00:01:14,360 --> 00:01:19,580
+المال وسنركز
+
+11
+00:01:19,580 --> 00:01:26,260
+على اتنين أفكار أهمالأدوات الرئيسية التي يستخدمها
+
+12
+00:01:26,260 --> 00:01:33,040
+الحكومة أو الشركة الأمريكية لإصلاح المال أو التحكم
+
+13
+00:01:33,040 --> 00:01:39,740
+في مصادر المال وكيفية تخطيط المزيد من المال ومصادر
+
+14
+00:01:39,740 --> 00:01:43,140
+المال الشركة
+
+15
+00:01:43,140 --> 00:01:46,660
+الأمريكية أو الشركة الأمريكية استخدمت أو استخدمت
+
+16
+00:01:46,660 --> 00:01:50,500
+ثلاث أدوات الرئيسية للتحكم في مصادر المال هذه
+
+17
+00:01:50,500 --> 00:01:56,260
+الأدواتالنسبة للاحتياط القانوني الاحتياط القانوني
+
+18
+00:01:56,260 --> 00:01:59,680
+الاحتياط القانوني الاحتياط القانوني الاحتياط
+
+19
+00:01:59,680 --> 00:02:00,840
+القانوني الاحتياط القانوني الاحتياط القانوني
+
+20
+00:02:00,840 --> 00:02:04,440
+الاحتياط
+
+21
+00:02:04,440 --> 00:02:04,940
+القانوني الاحتياط القانوني الاحتياط القانوني
+
+22
+00:02:04,940 --> 00:02:06,220
+الاحتياط القانوني الاحتياط القانوني الاحتياط
+
+23
+00:02:06,220 --> 00:02:06,280
+القانوني الاحتياط القانوني الاحتياط القانوني
+
+24
+00:02:06,280 --> 00:02:13,680
+الاحتياط قانوني الاحتياط
+
+25
+00:02:13,680 --> 00:02:21,800
+قانوني الاحتياطمثلًا، إذا كان لديك 100 دولار و كنت
+
+26
+00:02:21,800 --> 00:02:27,380
+تريد أن تضعه كدفع في بنك البلستيني، في هذه الحالة،
+
+27
+00:02:27,380 --> 00:02:32,260
+يجب أن يقوم بنك البلستيني بإختيار أو تقطيع جزء من
+
+28
+00:02:32,260 --> 00:02:35,160
+هذه المادة و يقوم بإختيارها في الشركة الأساسية.
+
+29
+00:02:37,560 --> 00:02:44,290
+قيمة الدفع هو ما يسمى كـ Required Reserve.الجزء
+
+30
+00:02:44,290 --> 00:02:47,990
+هذا اللي بنقصه من المية دولار نحطه في سلطة النقد
+
+31
+00:02:47,990 --> 00:02:53,490
+أو في البنك المركزي اسمه required reserve in order
+
+32
+00:02:53,490 --> 00:02:59,000
+to protect the deposits for the depositorsعشان
+
+33
+00:02:59,000 --> 00:03:03,280
+نحمي اللي هم الإيداعات أو الوذائع تباعت الناس اللي
+
+34
+00:03:03,280 --> 00:03:06,560
+بيحطوا مصاريهم في البنوك تمام؟ طيب، so suppose
+
+35
+00:03:06,560 --> 00:03:09,940
+that the required reserve ratio is the required
+
+36
+00:03:09,940 --> 00:03:15,440
+reserve ratio نسبة الاحتياط القانوني equals twenty
+
+37
+00:03:15,440 --> 00:03:20,940
+percent this means that the Bank of Palestine must
+
+38
+00:03:20,940 --> 00:03:25,040
+deduct twenty percent out of this deposit this is
+
+39
+00:03:25,040 --> 00:03:25,560
+a deposit
+
+40
+00:03:28,220 --> 00:03:34,020
+هي تسمى كتابة مالية 100 دولار في هذه الحالة، يجب
+
+41
+00:03:34,020 --> 00:03:38,880
+أن يقوم البنك بالفلسطينية باستخدام أو تقطيع 20% من
+
+42
+00:03:38,880 --> 00:03:43,480
+100 دولار ويقوم باستخدامه في الشركة الأساسية أو
+
+43
+00:03:43,480 --> 00:03:48,520
+الحكومة المالية البلسطينية، ففي هذه الحالة، مقاومة
+
+44
+00:03:48,520 --> 00:03:53,560
+المالية المطلوبة هي مقاومة المالية المطلوبة مرة
+
+45
+00:03:53,560 --> 00:03:54,900
+مرة مقاومة
+
+46
+00:03:59,390 --> 00:04:03,790
+المستقبل المطلوب يعني
+
+47
+00:04:03,790 --> 00:04:11,070
+كم هي مستقبل المطلوب 20% مرة مرة مرة مرة مرة مرة
+
+48
+00:04:11,070 --> 00:04:11,770
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+49
+00:04:11,770 --> 00:04:12,730
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+50
+00:04:12,730 --> 00:04:12,750
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+51
+00:04:12,750 --> 00:04:15,150
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+52
+00:04:15,150 --> 00:04:16,910
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+53
+00:04:16,910 --> 00:04:22,250
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مequals
+
+54
+00:04:22,250 --> 00:04:26,690
+هذا اللي هو الاحتياط المطلوب يلحق في سلطة النقد
+
+55
+00:04:26,690 --> 00:04:30,190
+equals twenty dollars in this case we have x's
+
+56
+00:04:30,190 --> 00:04:34,050
+reserve by how much eighty dollars يعني احتياط
+
+57
+00:04:34,050 --> 00:04:37,810
+الفقه ده بنقدر نتصرف فيه صح؟ so in this case the
+
+58
+00:04:37,810 --> 00:04:46,310
+x's reserve reserves equals the actual reserve
+
+59
+00:04:46,310 --> 00:04:52,200
+minus the required reserveأو المحافظات المجتمعية
+
+60
+00:04:52,200 --> 00:04:55,880
+المجتمعية
+
+61
+00:04:55,880 --> 00:04:57,280
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+62
+00:04:57,280 --> 00:04:57,860
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+63
+00:04:57,860 --> 00:04:57,920
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+64
+00:04:57,920 --> 00:04:58,780
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+65
+00:04:58,780 --> 00:05:01,900
+المجتمعية
+
+66
+00:05:01,900 --> 00:05:03,380
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+67
+00:05:03,380 --> 00:05:12,200
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+68
+00:05:12,200 --> 00:05:18,060
+المج
+
+69
+00:05:20,490 --> 00:05:25,810
+هو لا يستطيع أن يدفع الانتجار الكام لأنه يجب أن
+
+70
+00:05:25,810 --> 00:05:33,350
+يدفع 20% من هذا الانتجار وانتجاره في البنك أو
+
+71
+00:05:33,350 --> 00:05:37,050
+البنك الرئيسي أو الوظيفة الأمريكية أو الحكومة
+
+72
+00:05:37,050 --> 00:05:39,670
+المالية البلسانية كما تعرف في بلسطين
+
+73
+00:05:44,000 --> 00:05:49,000
+هذا هو أسلحة الأساسية أو أحد الأسلحة أو ثلاث أسلحة
+
+74
+00:05:49,000 --> 00:05:51,060
+التي يمكن استخدامها الشركة الأمريكية أو الوظيفة
+
+75
+00:05:51,060 --> 00:05:54,280
+الأمريكية لتحكم
+
+76
+00:05:54,280 --> 00:05:54,540
+مصادر الدولة الأمريكية لتحكم مصادر الدولة
+
+77
+00:05:54,540 --> 00:05:58,040
+الأمريكية لتحكم مصادر الدولة الأمريكية لتحكم مصادر
+
+78
+00:05:58,040 --> 00:06:01,860
+الدولة الأمريكية لتحكم
+
+79
+00:06:01,860 --> 00:06:02,080
+الدولة الأمريكية لتحكم مصادر الدولة الأمريكية
+
+80
+00:06:02,080 --> 00:06:08,200
+لتحكم مصادر الدولة الأمريكية لتحكم مصاد
+
+81
+00:06:09,210 --> 00:06:19,470
+إن المقاومة المتطلبة تزداد من 20% إلى 40% هذا يعني
+
+82
+00:06:19,470 --> 00:06:25,130
+ماذا؟ يتقلل المقاومة المتطلبة التي يمكنها البنك أن
+
+83
+00:06:25,130 --> 00:06:31,770
+تدفعها للجمهور او الناس بالضبط ففي هذه الحالة،
+
+84
+00:06:31,770 --> 00:06:37,450
+ستزداد أو تتقل المساعدة المالية؟ بالضبط، ستتقل
+
+85
+00:06:37,450 --> 00:06:41,290
+المساعدة الماليةصح ولا لأ؟ لأنه المسار عمليا صار
+
+86
+00:06:41,290 --> 00:06:43,810
+البنك اللي .. اللي قدر يقرضه من بنك فلسطين للناس
+
+87
+00:06:43,810 --> 00:06:46,930
+جلوة بتالس ال money supply would decline صح ولا
+
+88
+00:06:46,930 --> 00:06:51,090
+لأ؟ so we have an inverse relationship between the
+
+89
+00:06:51,090 --> 00:06:53,850
+required reserve ratio and money supply صح؟
+
+90
+00:06:53,850 --> 00:06:59,810
+exactly هلأ شو هذا معناه؟ انه لو راح البنك او ال
+
+91
+00:06:59,810 --> 00:07:02,190
+central bank او ال federal reserve system جالك انه
+
+92
+00:07:02,190 --> 00:07:05,470
+انا required reserve ratio بدل ما هو 20 بنقص 40
+
+93
+00:07:05,470 --> 00:07:09,310
+ونخليهم عند ال central bankعمليا بيبطل البنوك معاه
+
+94
+00:07:09,310 --> 00:07:11,830
+مصارى أو حجم الوثائع اللى موجودة عند البنوك اللى
+
+95
+00:07:11,830 --> 00:07:14,210
+بتتصرف فيها بتقل و بتقل ال money supply with what؟
+
+96
+00:07:14,210 --> 00:07:18,070
+with decline right؟ so there is an inverse
+
+97
+00:07:18,070 --> 00:07:21,370
+relationship between the required reserve ratio
+
+98
+00:07:21,370 --> 00:07:26,690
+and the money supplyهذا يعني أننا لدينا النتيجة
+
+99
+00:07:26,690 --> 00:07:30,690
+الأخيرة أو النظرية هي أن هناك علاقة عكسية بين
+
+100
+00:07:30,690 --> 00:07:32,370
+مقاومة المال والمقاومة المحتاجة لها ومقاومة المال
+
+101
+00:07:32,370 --> 00:07:33,610
+المحتاجة لها ومقاومة المال المحتاجة لها ومقاومة
+
+102
+00:07:33,610 --> 00:07:36,310
+المال المحتاجة لها ومقاومة المال المحتاجة لها
+
+103
+00:07:36,310 --> 00:07:39,030
+ومقاومة المال المحتاجة لها ومقاومة المال المحتاجة
+
+104
+00:07:39,030 --> 00:07:40,550
+لها ومقاومة المال المحتاجة لها ومقاومة المال
+
+105
+00:07:40,550 --> 00:07:40,870
+المال المحتاجة لها ومقاومة المال المحتاجة لها
+
+106
+00:07:40,870 --> 00:07:48,750
+ومقاومة المال المحتاجة لها ومقاالمدفع الثاني اللي
+
+107
+00:07:48,750 --> 00:07:50,790
+يستطيع استخدامه الشركة الرئيسية أو الشركة الرئيسية
+
+108
+00:07:50,790 --> 00:07:58,690
+هو اتفاق الدفع اتفاق الدفع اتفاق الدفع اتفاق الدفع
+
+109
+00:07:58,690 --> 00:08:04,530
+اتفاق الدفع اتفاق
+
+110
+00:08:04,530 --> 00:08:10,550
+الدفع
+
+111
+00:08:10,550 --> 00:08:16,830
+اتفاق الدفع
+
+112
+00:08:16,870 --> 00:08:24,690
+الدسكاوت ريت دسكاوت ريت
+
+113
+00:08:24,690 --> 00:08:30,190
+دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت
+
+114
+00:08:30,190 --> 00:08:30,250
+دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت
+
+115
+00:08:30,250 --> 00:08:34,650
+ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت
+
+116
+00:08:34,650 --> 00:08:45,530
+دسكاوت ريت دسكاوت ريت دسكاوت روانت ترغب ان تتخلص
+
+117
+00:08:45,530 --> 00:08:49,890
+من دولة او تأخذ دولة من هذه المصرفة انت يجب ان
+
+118
+00:08:49,890 --> 00:08:56,710
+تدفع اهتمامك كمستخدم اذا ذهبت إلى المصرفة التجارية
+
+119
+00:08:56,710 --> 00:09:00,770
+لتدفع دولة في هذه الحالة يجب ان تدفع اهتمامك انت
+
+120
+00:09:00,770 --> 00:09:05,110
+تدفع اهتمامك انت تدفع اهتمامك انت دفع اهتمامك انت
+
+121
+00:09:05,110 --> 00:09:05,350
+دفع اهتمامك انت دفع اهتمامك انت دفع اهتمامك انت
+
+122
+00:09:05,350 --> 00:09:06,650
+دفع اهتمامك انت دفع اهتمامك انت دفع اهتمامك انت
+
+123
+00:09:06,650 --> 00:09:10,510
+دفع اهتمام
+
+124
+00:09:11,240 --> 00:09:18,420
+أو اذا كان لديه إفلاس إذا كان بحاجة إلى المال أو
+
+125
+00:09:18,420 --> 00:09:24,720
+إذا كان بحاجة إلى المال من مركز التجارب يمكنه
+
+126
+00:09:24,720 --> 00:09:32,120
+الذهاب إلى مركز التجارب لإستغلال المال الوحيد اللي
+
+127
+00:09:32,120 --> 00:09:35,880
+كمان البنك التجارب يروح يقترض من من؟ من سلطة النقد
+
+128
+00:09:35,880 --> 00:09:40,810
+أو من البنك المركزيThey have to pay a discount
+
+129
+00:09:40,810 --> 00:09:43,550
+it's called or the cost of borrowing تكلفة
+
+130
+00:09:43,550 --> 00:09:45,830
+الاقتراض هذه من البنك التجاري from the central
+
+131
+00:09:45,830 --> 00:09:49,010
+bank is called the discount rate لأن هم بيدفعوا
+
+132
+00:09:49,010 --> 00:09:54,190
+interest كمان صح ال central bank باعترش الفلوس هيك
+
+133
+00:09:54,190 --> 00:09:57,690
+so we have what a discount rate the cost of
+
+134
+00:09:57,690 --> 00:10:00,470
+borrowing for the commercial banks from the
+
+135
+00:10:00,470 --> 00:10:02,630
+central bank or the federal reserve system is
+
+136
+00:10:02,630 --> 00:10:08,050
+called the discount rate سعر خصم تمام so suppose
+
+137
+00:10:08,050 --> 00:10:16,250
+thatأو سؤالي هو ماهي علاقة بين رقم التسكيب والمال
+
+138
+00:10:16,250 --> 00:10:24,770
+المستخدم؟ إذا رقم التسكيب أزداد
+
+139
+00:10:24,770 --> 00:10:29,290
+تسكيب المال المستخدم يعني سبوز أنه البنك المركزي
+
+140
+00:10:29,290 --> 00:10:33,210
+يقول لك والله أنا بدل بدأ أخد على السحبات بعتك
+
+141
+00:10:33,210 --> 00:10:36,350
+كبنك تجاري إذا بدأ أخد بدل ما أخد تلاتين في المية
+
+142
+00:10:36,350 --> 00:10:40,130
+بدي أخد سبعين في الميةتمام؟ و بيبطلوا .. بيبطلوا
+
+143
+00:10:40,130 --> 00:10:42,370
+البنوك التجارية تقترض منهم، مظبوط ولا لأ؟ و ابتدال
+
+144
+00:10:42,370 --> 00:10:45,250
+ال money supply هو what؟ هو ال decline، مظبوط ولا
+
+145
+00:10:45,250 --> 00:10:47,630
+لأ؟ لأن ال money supply هو الجزء منه هو اللي موجود
+
+146
+00:10:47,630 --> 00:10:52,130
+في ال .. ال commercial banks، صح شباب؟ So, there
+
+147
+00:10:52,130 --> 00:10:54,490
+is an inverse relationship between the discount
+
+148
+00:10:54,490 --> 00:10:56,310
+rate and money supply, yes
+
+149
+00:10:59,350 --> 00:11:06,010
+القيمة التي ذكرتها هي قيمة الانتجار من الشركات
+
+150
+00:11:06,010 --> 00:11:09,950
+التقليدية من الشركة التقليدية، إذا كان الشركة
+
+151
+00:11:09,950 --> 00:11:15,630
+التقليدية بحاجة إلى المال و ذهبت إلى الشركة
+
+152
+00:11:15,630 --> 00:11:21,040
+التقليدية لتلقى دفعةهو يجب أن يدفع اهتمام ما يدفع
+
+153
+00:11:21,040 --> 00:11:25,200
+اهتمام هذا الاهتمام يسمى بـ Discount Rate اعتبر ان
+
+154
+00:11:25,200 --> 00:11:28,060
+الشركة الأساسية قررت ان تزيد اهتمام الـDiscount
+
+155
+00:11:28,060 --> 00:11:32,640
+Rate بيقولهم ان سعر الاقتراض عالي بديش اخليه 20%
+
+156
+00:11:32,640 --> 00:11:35,420
+بدي اخليه 60% و بدي اخليه 50% في هذه الحالة ماذا
+
+157
+00:11:35,420 --> 00:11:40,320
+سيحدث؟ مصادر المال اللي متوفر في مصادر الشركات
+
+158
+00:11:40,320 --> 00:11:43,540
+التقليدية لتحفزها في هذه الحالة ماذا سيحدث؟
+
+159
+00:11:43,540 --> 00:11:46,120
+ستتخلص. لذلك مصادر المال بالعام ستتخلص
+
+160
+00:11:50,380 --> 00:11:54,840
+النهاية، لدينا علاقة عادية بين عدد المساعدة
+
+161
+00:11:54,840 --> 00:11:58,420
+والمساعدة والمساعدة والمساعدة والمساعدة والمساعدة
+
+162
+00:11:58,420 --> 00:12:04,680
+والمساعدة والمساعدة والمساعدة
+
+163
+00:12:04,680 --> 00:12:07,600
+والمساعدة والمساعدة
+
+164
+00:12:13,460 --> 00:12:17,060
+القاعدة تبعتنا هي القاعدة تبعتنا في انفرس
+
+165
+00:12:17,060 --> 00:12:21,080
+relationship between record ratio and money supply
+
+166
+00:12:21,080 --> 00:12:24,200
+as well as انفرس relationship between the discount
+
+167
+00:12:24,200 --> 00:12:26,860
+rate and money supply what about the last point
+
+168
+00:12:26,860 --> 00:12:29,340
+which is or the last tool that the central bank
+
+169
+00:12:29,340 --> 00:12:33,260
+can use or uses in order to control the money
+
+170
+00:12:33,260 --> 00:12:37,850
+supply the last point isالعملات في السوق المفتوحة
+
+171
+00:12:37,850 --> 00:12:41,470
+في السوق المفتوحة فهذه هي الأولى هذه هي الطريقة
+
+172
+00:12:41,470 --> 00:12:45,590
+الثانية الطريقة الثالثة هي العملات في السوق
+
+173
+00:12:45,590 --> 00:12:49,010
+المفتوحة في السوق المفتوحة
+
+174
+00:13:05,410 --> 00:13:10,530
+of bonds عادي لو انه suppose that ال central bank
+
+175
+00:13:10,530 --> 00:13:16,390
+would like to increase the money supply بيشتر
+
+176
+00:13:16,390 --> 00:13:20,710
+ورق و بيعطيهم مصاريبيشتري securities و bonds و هيك
+
+177
+00:13:20,710 --> 00:13:25,190
+و بيعطيهم مصارى، so in this case if the central
+
+178
+00:13:25,190 --> 00:13:28,910
+bank would like to increase the money supply بيزود
+
+179
+00:13:28,910 --> 00:13:31,050
+المصارى في دنيا الناس مش بيعمل، بيشتري منهم الورق
+
+180
+00:13:31,050 --> 00:13:35,670
+اللي موجود معاهم، so in this case it can purchase
+
+181
+00:13:35,670 --> 00:13:42,450
+or buySecurities or bonds and so on صح؟ and if you
+
+182
+00:13:42,450 --> 00:13:45,450
+.. if the banks or the central bank would like to
+
+183
+00:13:45,450 --> 00:13:47,950
+decrease the money supply بدي أسحب المسار من دين
+
+184
+00:13:47,950 --> 00:13:52,130
+الناس إيش ببيعهم؟ بعطيهم ورق و باخد مساري so in
+
+185
+00:13:52,130 --> 00:13:56,170
+this case it can what? sell securities or bonds
+
+186
+00:13:56,170 --> 00:14:02,430
+treasure bonds and notes تمام؟ صعب؟ بس يعني ببيعهم
+
+187
+00:14:02,430 --> 00:14:04,830
+ورق و باخد منهم الفلوس و بتاع ليه in this case the
+
+188
+00:14:04,830 --> 00:14:08,770
+money supply would decline right؟الان دعونا نذهب
+
+189
+00:14:08,770 --> 00:14:14,790
+إلى مجالات مختلفة أو مجالات مرتبطة بالمقاومة
+
+190
+00:14:14,790 --> 00:14:21,230
+والمقاومة المتطلبة ومشكلة مختلفة مرتبطة بالمال
+
+191
+00:14:21,230 --> 00:14:24,350
+المستعمر لذلك كما ترى المقاومة
+
+192
+00:14:27,420 --> 00:14:31,100
+means the total reserves are what the deposit that
+
+193
+00:14:31,100 --> 00:14:35,020
+the bank has at the federal reserve a reserve bank
+
+194
+00:14:35,020 --> 00:14:38,440
+plus it cashed on hand the required reserve ratio
+
+195
+00:14:38,440 --> 00:14:42,720
+اللي هو هذا نسبة الاحتياط القانوني what is it is
+
+196
+00:14:42,720 --> 00:14:45,880
+the percentage of its total deposits that the
+
+197
+00:14:45,880 --> 00:14:49,000
+banks must keep as a reserves at the federal
+
+198
+00:14:49,000 --> 00:14:52,620
+reserve system اللي وضحناه تمام؟ طيب
+
+199
+00:14:58,590 --> 00:15:04,990
+الخطوات المتوفرة هي او اقل الخطوات الحقيقية او اقل
+
+200
+00:15:04,990 --> 00:15:13,690
+الخطوات المتوفرة او اقل الخطوات المتوفرة او اقل
+
+201
+00:15:13,690 --> 00:15:18,370
+الخطوات المتوفرة او اقل الخطوات
+
+202
+00:15:18,370 --> 00:15:27,270
+المتوفرة او اقل
+
+203
+00:15:27,270 --> 00:15:36,970
+الخطوات المتوفرةطيب .. اعتبر .. لنذهب
+
+204
+00:15:36,970 --> 00:15:44,010
+لهذا المثال أو التعليم .. كما ترى .. إذا كانت
+
+205
+00:15:44,010 --> 00:15:53,150
+المقاومة المطلوبة هي 20 شخص .. فالبنك لديه مقاومة
+
+206
+00:15:53,150 --> 00:15:59,800
+مقاومة ماذا؟ 80 دولارمع 80 دولار اكتشف مقاومة 100
+
+207
+00:15:59,800 --> 00:16:06,200
+دولار اكتشف مقاومة 100 دولار اكتشف مقاومة 100
+
+208
+00:16:06,200 --> 00:16:10,260
+دولار اكتشف مقاومة 100 دولار اكتشف مقاومة 100
+
+209
+00:16:10,260 --> 00:16:12,500
+دولار اكتشف مقاومة 100 دولار اكتشف مقاومة 100
+
+210
+00:16:12,500 --> 00:16:17,160
+دولار اكتشف مقاومة 100 دولار اكتشف
+
+211
+00:16:17,160 --> 00:16:19,660
+مقاومة 100 دولار اكتشف مقاومة 100 دولار اكتشف
+
+212
+00:16:19,660 --> 00:16:19,800
+مقاومة 100 دولار اكتشف مقاومة 100 دولار اكتشف
+
+213
+00:16:19,800 --> 00:16:22,160
+مقاومة 100 دولار اكتشف مقاومة 100 دولار اكتشف
+
+214
+00:16:22,160 --> 00:16:27,460
+مقاومة 100 دولار اكتشف مقاequals twenty person
+
+215
+00:16:27,460 --> 00:16:31,660
+times five hundred كده اندي reserves one hundred
+
+216
+00:16:31,660 --> 00:16:34,920
+هذا required reserve كله مظبوط وفي اندي loans كده
+
+217
+00:16:34,920 --> 00:16:38,760
+اش بقدر اعمل four hundred خلي بقدر اروح على اشي
+
+218
+00:16:38,760 --> 00:16:48,200
+اوضح ادحن
+
+219
+00:16:48,200 --> 00:16:49,140
+رجعله هال gate
+
+220
+00:16:57,970 --> 00:17:16,530
+لأ كله رجال له هذا عشان الله نفسي Now
+
+221
+00:17:16,530 --> 00:17:22,690
+suppose that we have the following example The
+
+222
+00:17:22,690 --> 00:17:26,150
+first charter bank has assets and liabilities
+
+223
+00:17:27,730 --> 00:17:31,050
+الليابيتيز .. نحن لدينا ديبوزيت نت وورث و
+
+224
+00:17:31,050 --> 00:17:36,490
+الليابيتيز عامة .. لذا كما ترى ديبوزيت يعني كم؟
+
+225
+00:17:36,490 --> 00:17:42,570
+800، صحيح؟ نت وورث يعني 400، هدول اللي بقدر يتصرف،
+
+226
+00:17:42,570 --> 00:17:45,690
+اللي مقدرش يتصرف فيهم البنك، خلينا نشوف، لنذهب
+
+227
+00:17:45,690 --> 00:17:50,790
+للتعاملاتاستخدام الاسم الموجود في الاسم الموجود في
+
+228
+00:17:50,790 --> 00:17:51,730
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+229
+00:17:51,730 --> 00:17:55,410
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+230
+00:17:55,410 --> 00:17:59,010
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+231
+00:17:59,010 --> 00:17:59,030
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+232
+00:17:59,030 --> 00:17:59,790
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+233
+00:17:59,790 --> 00:18:03,170
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+234
+00:18:03,170 --> 00:18:03,470
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+235
+00:18:03,470 --> 00:18:05,330
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+236
+00:18:05,330 --> 00:18:07,090
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+237
+00:18:07,090 --> 00:18:12,910
+الاسم الموجود في الاسم الموجود في الاس
+
+238
+00:18:14,610 --> 00:18:19,370
+اللي ا suppose انه ال deposit equal كدهش؟ 800 و
+
+239
+00:18:19,370 --> 00:18:23,870
+عند ال required reserve ratio كدهش؟ 25% كدهش بيكون
+
+240
+00:18:23,870 --> 00:18:29,410
+فيه عند ال reserves؟ 865% exactly so the reserves
+
+241
+00:18:29,410 --> 00:18:34,690
+in this
+
+242
+00:18:34,690 --> 00:18:36,750
+case the reserves equals
+
+243
+00:18:44,280 --> 00:18:51,240
+equals deposit times the required reserve ratio
+
+244
+00:18:51,240 --> 00:18:55,580
+طبعا هذا when x is reserved بيساوى صفر لأنه بيقول
+
+245
+00:18:55,580 --> 00:18:58,240
+ليه مافيش عند x is reserves وبالتالي ال reserves
+
+246
+00:18:58,240 --> 00:19:00,700
+كله إيش بيساوي بيساوي required reserve يعني بترجع
+
+247
+00:19:00,700 --> 00:19:03,680
+للسؤال هيك شو شباب؟
+
+248
+00:19:06,330 --> 00:19:10,710
+هذا بيقولنا و انه ايش انه if the first chartered
+
+249
+00:19:10,710 --> 00:19:14,070
+bank is meeting its reserves requirements and has
+
+250
+00:19:14,070 --> 00:19:17,590
+no excess reserves لما بيكون فيش اندي excess
+
+251
+00:19:17,590 --> 00:19:20,790
+reserves يعني excess reserves equals قداش Zero
+
+252
+00:19:20,790 --> 00:19:23,650
+يعني ال reserves في هذا الحالة ان ال reserves كله
+
+253
+00:19:23,650 --> 00:19:28,030
+ايش بيسوي لأ لابد ارجع لل law طبعا لل formula
+
+254
+00:19:28,030 --> 00:19:30,710
+reserves كله total reserves هذا لما بحكي في
+
+255
+00:19:30,710 --> 00:19:36,160
+reserves بحكي في total reserves equalsالـ Required
+
+256
+00:19:36,160 --> 00:19:39,280
+Reserves plus ال Excess Reserves
+
+257
+00:19:47,090 --> 00:19:51,470
+X's هل هو قولي انه if the X's reserves equals 0
+
+258
+00:19:51,470 --> 00:19:54,190
+معناه الكلام انه ال total reserves اللي هو ال
+
+259
+00:19:54,190 --> 00:19:57,710
+reserves هذا بيساوي ال quadreserves صح؟ هي السؤال
+
+260
+00:19:57,710 --> 00:20:01,290
+هيك so let's come back to the question لما يعطينا
+
+261
+00:20:01,290 --> 00:20:05,410
+that quadreserve ratio is 25% إذا كان ال X's
+
+262
+00:20:05,410 --> 00:20:10,150
+reserves يساوي صفر قداش في عندى the question is
+
+263
+00:20:10,150 --> 00:20:15,810
+its reserves قداش اللي هو عمليا reserves هذا قداش
+
+264
+00:20:15,810 --> 00:20:21,270
+بيساويit equals deposits times times required
+
+265
+00:20:21,270 --> 00:20:25,370
+reserve ratio لأنه ال reserves هو يساوي required
+
+266
+00:20:25,370 --> 00:20:30,430
+reserves في هذه الحالة لأن هذا صفر صح؟ so it
+
+267
+00:20:30,430 --> 00:20:37,710
+equals eight hundred dollars times zero point
+
+268
+00:20:37,710 --> 00:20:40,670
+twenty five كدهش هذا بيكون؟
+
+269
+00:20:43,260 --> 00:20:46,760
+So in this case the reserves equals 200 اللي في ال
+
+270
+00:20:46,760 --> 00:20:49,440
+exercise اللي جاي هتوضح الصورة بشكل أوضح بس لإنه
+
+271
+00:20:49,440 --> 00:20:55,020
+هذا the first example طب ال loans قدش بيخطط اللي
+
+272
+00:20:55,020 --> 00:20:57,660
+ال total ال total لازم ال liabilities equals
+
+273
+00:20:57,660 --> 00:21:01,260
+assets لازم ال assets تساوي ال liabilities
+
+274
+00:21:01,260 --> 00:21:07,920
+وبالتالي ال total must equal 1200 إذا قدش فيه in
+
+275
+00:21:07,920 --> 00:21:11,160
+the loans بيقدر يعطيه؟ 1000
+
+276
+00:21:14,100 --> 00:21:21,220
+صح؟ تمام؟ طيب so the question is how much is the
+
+277
+00:21:21,220 --> 00:21:27,820
+reserve? 200 و ال total assets equals one hundred
+
+278
+00:21:27,820 --> 00:21:29,000
+.. تمام؟
+
+279
+00:21:31,360 --> 00:21:35,720
+اللي بعد هو بيقولنا انه its loans equals how much
+
+280
+00:21:35,720 --> 00:21:40,400
+one thousand بعدين اللي هو ال total assets one
+
+281
+00:21:40,400 --> 00:21:43,460
+thousand two hundred طب let's go to this example
+
+282
+00:21:43,460 --> 00:21:49,480
+the
+
+283
+00:21:49,480 --> 00:21:53,740
+first commercial bank has the following assets and
+
+284
+00:21:53,740 --> 00:21:56,580
+liabilities right the information about the
+
+285
+00:21:56,580 --> 00:22:02,270
+liabilities are givenThe total assets equals the
+
+286
+00:22:02,270 --> 00:22:07,630
+total liabilities, right؟ طيب As
+
+287
+00:22:07,630 --> 00:22:10,930
+you see, the total reserves equals how much؟
+
+288
+00:22:10,930 --> 00:22:15,550
+800000$، صح؟ كدهش في عندنا required reserve؟ 200
+
+289
+00:22:15,550 --> 00:22:24,030
+كدهش ال excess reserve؟ Exactly، متممتها 600000$،
+
+290
+00:22:24,030 --> 00:22:31,180
+صح؟ كدهش في عندى loans، إذن؟ اللي هو2 مليون و نص 2
+
+291
+00:22:31,180 --> 00:22:37,600
+.5 مليون minus ال reserves صحش بقى؟ أثبت ولا لأ؟
+
+292
+00:22:37,600 --> 00:22:42,860
+مين مش فاهم طيب ال total assets عبارة عن إيش ال
+
+293
+00:22:42,860 --> 00:22:48,060
+reserves plus ال loans صح؟ وبالتالي ال total أو ال
+
+294
+00:22:48,060 --> 00:22:51,180
+loans بيساوي 2 مليون و نص ناقص 800 ألف جدش بيكون
+
+295
+00:22:51,180 --> 00:23:04,670
+مليون و سبعمية ألف 1.7 خلاص مليونأو هذا
+
+296
+00:23:04,670 --> 00:23:10,390
+كل شيء تمام؟ طيب، فالسؤال هو تفضل للأسفل، أولاً،
+
+297
+00:23:10,390 --> 00:23:17,510
+كمية محافظة X كمية محافظة X هو كم؟ تمام، ورقم
+
+298
+00:23:17,510 --> 00:23:21,650
+محافظة محافظة محافظة محافظة محافظة محافظة محافظة
+
+299
+00:23:21,650 --> 00:23:22,430
+محافظة محافظة محافظة محافظة محافظة محافظة محافظة
+
+300
+00:23:22,430 --> 00:23:24,870
+محافظة محافظة محافظة محافظة محافظة محافظة محافظة
+
+301
+00:23:24,870 --> 00:23:25,970
+محافظة محافظة محافظة محافظة محافظة محافظة محافظة
+
+302
+00:23:25,970 --> 00:23:28,930
+محافظة محافظة محافظة محافظة مSo، كدهش الـ Required
+
+303
+00:23:28,930 --> 00:23:36,810
+Reserve Ratio؟ Required Reserve Ratio equals
+
+304
+00:23:36,810 --> 00:23:41,570
+Required
+
+305
+00:23:41,570 --> 00:23:48,070
+Reserves over Deposits طبعا
+
+306
+00:23:48,070 --> 00:23:48,830
+مضروب في 100%
+
+307
+00:23:54,120 --> 00:23:58,520
+بالنسبة لهذه الحالة دعونا نعود إلى المعلومات كما
+
+308
+00:23:58,520 --> 00:24:01,520
+ترى مقارنة المقارنة المطلوبة بالمقارنة المطلوبة
+
+309
+00:24:01,520 --> 00:24:05,660
+بالمقارنة المطلوبة بالمقارنة المطلوبة بالمقارنة
+
+310
+00:24:05,660 --> 00:24:05,780
+المطلوبة المطلوبة المطلوبة المطلوبة المطلوبة
+
+311
+00:24:05,780 --> 00:24:08,060
+المطلوبة المطلوبة المطلوبة المطلوبة المطلوبة
+
+312
+00:24:08,060 --> 00:24:09,640
+المطلوبة المطلوبة المطلوبة المطلوبة المطلوبة
+
+313
+00:24:09,640 --> 00:24:13,800
+المطلوبة المطلوبة المطلوبة
+
+314
+00:24:13,800 --> 00:24:19,860
+المطلوبة المطلوبة المطلوبة المطلوبة المطلوبة
+
+315
+00:24:19,860 --> 00:24:21,500
+المطل
+
+316
+00:24:23,980 --> 00:24:29,000
+x100 وبالتالي هذا بيساوي عشرة في المية that's it
+
+317
+00:24:29,000 --> 00:24:36,180
+تمام okay مين
+
+318
+00:24:36,180 --> 00:24:41,360
+مش فاهم طيب اعيد لون اه شباب حبابي مين اعيد لون
+
+319
+00:24:41,360 --> 00:24:46,440
+okay okay
+
+320
+00:24:46,440 --> 00:24:50,060
+the first commercial bank total loans equals قداش
+
+321
+00:24:50,060 --> 00:24:57,770
+how muchحسبناها one million seven hundred thousand
+
+322
+00:24:57,770 --> 00:25:02,150
+dollars the
+
+323
+00:25:02,150 --> 00:25:06,130
+last دي the answer is دي okay let's go to this
+
+324
+00:25:06,130 --> 00:25:14,210
+example طبعا
+
+325
+00:25:14,210 --> 00:25:17,450
+هذا أجى بالامتحان ال .. بال final exam المرة
+
+326
+00:25:17,450 --> 00:25:23,760
+الماضيةكما ترى لدينا مصالح او مصالح المساواة مصالح
+
+327
+00:25:23,760 --> 00:25:26,260
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+328
+00:25:26,260 --> 00:25:29,260
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+329
+00:25:29,260 --> 00:25:30,620
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+330
+00:25:30,620 --> 00:25:30,640
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+331
+00:25:30,640 --> 00:25:32,220
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+332
+00:25:32,220 --> 00:25:36,120
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+333
+00:25:36,120 --> 00:25:41,660
+مصالح م
+
+334
+00:25:47,840 --> 00:25:54,920
+دفع خمس عشر ألف دولار، كم هو مجموعه؟ ثلاث
+
+335
+00:25:54,920 --> 00:26:00,080
+عشر ألف دولار، كم هو مجموعه؟ ثلاث عشر ألف دولار،
+
+336
+00:26:00,080 --> 00:26:07,140
+كم هو مجموعه؟ ثلاث عشر ألف دولار، كم هو مجموعه؟
+
+337
+00:26:10,110 --> 00:26:15,910
+exactly 500000$ thank you تمام طيب so how much is
+
+338
+00:26:15,910 --> 00:26:19,310
+the required reserve ratio the required reserve
+
+339
+00:26:19,310 --> 00:26:23,030
+ratio equals the required reserve over deposits
+
+340
+00:26:23,030 --> 00:26:33,430
+قداش 100100000 over 500$ قداش 20%مظبوط twenty
+
+341
+00:26:33,430 --> 00:26:37,110
+percent so the required reserve equals twenty
+
+342
+00:26:37,110 --> 00:26:41,810
+percent what else ال excess reserve equals how
+
+343
+00:26:41,810 --> 00:26:45,530
+much exactly two hundred it's already calculated
+
+344
+00:26:45,530 --> 00:26:50,050
+هيها ال loans five hundred و ال net worth three
+
+345
+00:26:50,050 --> 00:26:58,610
+hundred these are the questions طيب crescent اه
+
+346
+00:26:58,610 --> 00:27:00,950
+هذا another question
+
+347
+00:27:07,320 --> 00:27:12,600
+Crescent City Bank لديها 2 مليون دفعات، فالدفع يقل
+
+348
+00:27:12,600 --> 00:27:19,960
+كم؟ 2 مليون، فالدفع يقل
+
+349
+00:27:19,960 --> 00:27:22,100
+200 مليون
+
+350
+00:27:26,190 --> 00:27:29,210
+Crescent City Bank is meeting its reserve
+
+351
+00:27:29,210 --> 00:27:33,430
+requirement and has no excess reserves. This means
+
+352
+00:27:33,430 --> 00:27:37,230
+ان ال excess reserves equals كداش؟ Zero. So عند ال
+
+353
+00:27:37,230 --> 00:27:44,370
+excess reserves equals zero. Or this means ان ال
+
+354
+00:27:44,370 --> 00:27:49,910
+reserves كله equals required reserve. شايف معناه؟
+
+355
+00:27:51,100 --> 00:27:54,020
+بسبب ان الاختصارات المحتاجة او الاختصارات المحتاجة
+
+356
+00:27:54,020 --> 00:27:56,920
+او الاختصارات المحتاجة او الاختصارات المحتاجة او
+
+357
+00:27:56,920 --> 00:28:00,840
+الاختصارات المحتاجة او الاختصارات المحتاجة او
+
+358
+00:28:00,840 --> 00:28:07,100
+الاختصارات المحتاجة او الاختصارات
+
+359
+00:28:07,100 --> 00:28:16,110
+المحتاجةطيب، لنعود إلى التعليم، لديه 40 مليون في
+
+360
+00:28:16,110 --> 00:28:19,210
+محافظات، يعني عند الـ required reserves أو
+
+361
+00:28:19,210 --> 00:28:27,050
+محافظات، كداش؟ 40، لذا، محافظات أو محافظات محتاجة
+
+362
+00:28:27,050 --> 00:28:32,210
+تقريبا 40 مليون، صحيح؟ مركز أو محافظة أو محافظة
+
+363
+00:28:32,210 --> 00:28:38,620
+تقريبا كداش؟ 30%exactly مظبوط so the required
+
+364
+00:28:38,620 --> 00:28:44,320
+reserve ratio equals the required reserves over
+
+365
+00:28:44,320 --> 00:28:48,440
+deposits equals
+
+366
+00:28:48,440 --> 00:28:53,400
+four hundred over two hundred كدهش بيطلع هذا
+
+367
+00:28:53,400 --> 00:29:01,680
+twenty percent that's it صعب ايه طب مين مش فاهم
+
+368
+00:29:01,680 --> 00:29:11,650
+ايدلهطيب لنذهب لهذا المثال ناريان ناشنال بنك لديه
+
+369
+00:29:11,650 --> 00:29:17,230
+750 دولار او مليون دولار في المقاومات لذا مقاومة
+
+370
+00:29:17,230 --> 00:29:27,790
+كم؟ مقاومة 750
+
+371
+00:29:27,790 --> 00:29:35,090
+مليون دولارالمقاومة المطلوبة هي 30% المقاومة
+
+372
+00:29:35,090 --> 00:29:41,750
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+373
+00:29:41,750 --> 00:29:44,190
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+374
+00:29:44,190 --> 00:29:45,190
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+375
+00:29:45,190 --> 00:29:46,410
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+376
+00:29:46,410 --> 00:29:48,070
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+377
+00:29:48,070 --> 00:29:49,110
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+378
+00:29:49,110 --> 00:29:49,710
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+379
+00:29:49,710 --> 00:29:57,810
+المطلوبة هي 30% المقاومة المطلوبة هي 30
+
+380
+00:29:57,810 --> 00:30:10,250
+% المق0.30 x 750 equals 225 مليون دولار this is
+
+381
+00:30:10,250 --> 00:30:17,950
+the required reserve ratio طيب كده يكون عندهم اللي
+
+382
+00:30:17,950 --> 00:30:23,950
+هو ال X is reserve in this case 750 minus 250
+
+383
+00:30:23,950 --> 00:30:27,610
+exactly اللي هو ال X is reserve in this case مجلدش
+
+384
+00:30:27,610 --> 00:30:33,150
+انه يسوى صفر equals zeroالخطوة التالية هي خطوة
+
+385
+00:30:33,150 --> 00:30:34,110
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+386
+00:30:34,110 --> 00:30:39,290
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+387
+00:30:39,290 --> 00:30:44,150
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+388
+00:30:44,150 --> 00:30:44,970
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+389
+00:30:44,970 --> 00:30:45,230
+الاستخدم الاستخدم الاستخدم الاستخدم الاستخدم
+
+390
+00:30:45,230 --> 00:30:52,190
+الاستخدم الاستخدم
+
+391
+00:30:52,190 --> 00:31:00,200
+الاانترا كوستال بانك لديه 5 مليون ديبوزيت و 500
+
+392
+00:31:00,200 --> 00:31:05,420
+ألف محافظة خليني
+
+393
+00:31:05,420 --> 00:31:10,780
+نشوف نعمل تجزئة للبيانات و نشوف شو الحقيقه فالسؤال
+
+394
+00:31:10,780 --> 00:31:20,800
+هو اذا ان الديبوزيت ايه كم؟ ديبوزيت
+
+395
+00:31:23,280 --> 00:31:39,260
+equals 500000$ 500000
+
+396
+00:31:39,260 --> 00:31:47,780
+$ in reserves 500000
+
+397
+00:31:47,780 --> 00:32:06,000
+$إذا كانت مقاومة الـ RRR مقاومة 5% إذا
+
+398
+00:32:06,000 --> 00:32:15,300
+كانت مقاومة الـ
+
+399
+00:32:15,300 --> 00:32:18,680
+RRR مقاومة 5% إذا كانت مقاومة الـ RRR مقاومة 5%
+
+400
+00:32:22,880 --> 00:32:27,240
+الأموال المطلوبة مطلوبة مطلوبة مطلوبة مطلوبة
+
+401
+00:32:27,240 --> 00:32:29,820
+مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة
+
+402
+00:32:29,820 --> 00:32:34,600
+مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة
+
+403
+00:32:34,600 --> 00:32:34,980
+مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة
+
+404
+00:32:34,980 --> 00:32:35,040
+مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة
+
+405
+00:32:35,040 --> 00:32:39,940
+مطلوبة مطلوبة مطلوبة مطلوب
+
+406
+00:32:42,860 --> 00:32:46,500
+هنا إيش؟ this is the required reserve طب قديش ال
+
+407
+00:32:46,500 --> 00:32:49,780
+excess reserve? how much is the excess reserve?
+
+408
+00:32:50,160 --> 00:32:54,320
+exactly total reserves minus the required reserves
+
+409
+00:32:54,320 --> 00:33:01,160
+so the excess reserve equals
+
+410
+00:33:01,160 --> 00:33:08,860
+the total reserves or reserves minus the required
+
+411
+00:33:08,860 --> 00:33:14,470
+reservesصح؟ so equals five hundred thousand
+
+412
+00:33:14,470 --> 00:33:18,110
+dollars minus two hundred fifty thousand dollars
+
+413
+00:33:18,110 --> 00:33:23,390
+equals two hundred fifty thousand dollars that's
+
+414
+00:33:23,390 --> 00:33:31,770
+it صعب الأمور؟ ده ده ده طيب let's go to another
+
+415
+00:33:31,770 --> 00:33:41,800
+questionالبنك في أسيا لديه نفس الشيء أعتقد دبوزيت
+
+416
+00:33:41,800 --> 00:33:49,260
+980 ألف محافظة و 9 مليون دبوزيت و مقارنة المحافظة
+
+417
+00:33:49,260 --> 00:33:51,340
+الواحدة 10% كمية محافظة ال X
+
+418
+00:33:56,780 --> 00:34:04,840
+حسنًا، مصدر Red Oak لديه 2 مليون دفعات و 400 ألف
+
+419
+00:34:04,840 --> 00:34:11,300
+محافظة إذا كانت محافظة الـ X هي 800 ألف دولار، كم
+
+420
+00:34:11,300 --> 00:34:19,480
+هي محافظة الريكويد؟ دعنا نجزء البيانات، كما ترى،
+
+421
+00:34:19,480 --> 00:34:31,950
+المحافظة هي كميةمدفعات كم؟ 2 مليون 400000
+
+422
+00:34:31,950 --> 00:34:38,130
+$ 400000
+
+423
+00:34:38,130 --> 00:34:52,350
+$ وإذا مقاومة X مقاومة X مقاومة X مقاومة X مقاومة
+
+424
+00:34:52,350 --> 00:34:58,090
+X 100000$ماذا يعني عدد عدد المحافظة المطلوبة؟ يجب
+
+425
+00:34:58,090 --> 00:35:00,570
+أن نتكلم عن عدد المحافظة المطلوبة ومن ثم عدد
+
+426
+00:35:00,570 --> 00:35:11,710
+المحافظة المطلوبة
+
+427
+00:35:14,550 --> 00:35:17,530
+because total reserves لما بيقولي reserves على طول
+
+428
+00:35:17,530 --> 00:35:20,870
+بيعرف بفهم انه بيحكي عن total reserves تمام؟ so
+
+429
+00:35:20,870 --> 00:35:25,270
+reserves انت كدهش؟ four hundred thousand dollars
+
+430
+00:35:25,270 --> 00:35:29,930
+minus x's reserves one hundred thousand three
+
+431
+00:35:29,930 --> 00:35:35,250
+hundred thousand dollars so how much is the
+
+432
+00:35:35,250 --> 00:35:40,870
+required reserve ratio أبو جزر؟So the required
+
+433
+00:35:40,870 --> 00:35:45,250
+reserve ratio equals required reserves over
+
+434
+00:35:45,250 --> 00:35:49,070
+deposits equals
+
+435
+00:35:49,070 --> 00:35:57,130
+300000 over 2 million dollars equals how much
+
+436
+00:35:57,130 --> 00:36:07,920
+exactly 15% right صعب الأمورلنذهب إلى هذا المثال
+
+437
+00:36:07,920 --> 00:36:14,620
+كما ترى كل شيء مُعطلوب هنا كما
+
+438
+00:36:14,620 --> 00:36:22,860
+ترى مقالات المالية 1.2 مليون ومقالات المالية 6.8
+
+439
+00:36:22,860 --> 00:36:31,300
+ومقالات المالية 8 مليون ومقالات المالية 8 مليون
+
+440
+00:36:31,300 --> 00:36:33,840
+ومقالات المالية 8 مليون ومقالات المالية 8 مليون
+
+441
+00:36:36,840 --> 00:36:41,340
+Okay, let's go to the exercise of the required
+
+442
+00:36:41,340 --> 00:36:44,840
+reserve ratio if the required reserve ratio equals
+
+443
+00:36:44,840 --> 00:36:50,920
+or is is 15% the first charter bank is what؟ يعني
+
+444
+00:36:50,920 --> 00:36:54,480
+لو suppose ان required reserves عندي ratio بيساوي
+
+445
+00:36:54,480 --> 00:36:58,080
+15% كداش عندي required reserves في هذا الحالة in
+
+446
+00:36:58,080 --> 00:37:02,940
+this case عشان نشوف شو هوضع ال bank So as you see
+
+447
+00:37:02,940 --> 00:37:12,390
+ان required reserve ratioequals 15% required
+
+448
+00:37:12,390 --> 00:37:18,670
+reserve ratio equals 15% right ومعطيني reserves
+
+449
+00:37:18,670 --> 00:37:22,930
+بيسوي 1.2 طب قديش ال required reserve هذا السؤال
+
+450
+00:37:22,930 --> 00:37:26,090
+عشان أشوف شو وضع البنك how much is the required
+
+451
+00:37:26,090 --> 00:37:32,590
+reserve required reserve ratio times deposits صح
+
+452
+00:37:34,130 --> 00:37:42,430
+equals 15% times deposits 8 million equals how
+
+453
+00:37:42,430 --> 00:37:51,030
+much? 1.2 مليون دولار معناه الكلام ايش ان ال
+
+454
+00:37:51,030 --> 00:37:54,090
+required reserve ratio او sorry required reserve
+
+455
+00:37:54,090 --> 00:37:57,870
+بتسوي ايش؟ reserves وبالتالي X is reserve ايش ماله
+
+456
+00:37:57,870 --> 00:38:02,940
+يسوي؟إذا كانت المقاومة X صفر بساوي صفر بساوي صفر
+
+457
+00:38:02,940 --> 00:38:03,280
+بساوي صفر بساوي صفر بساوي صفر بساوي صفر بساوي صفر
+
+458
+00:38:03,280 --> 00:38:06,460
+بساوي صفر بساوي صفر بساوي صفر بساوي صفر بساوي صفر
+
+459
+00:38:06,460 --> 00:38:09,420
+بساوي صفر بساوي صفر بساوي صفر بساوي صفر بساوي صفر
+
+460
+00:38:09,420 --> 00:38:11,480
+بساوي صفر بساوي صفر بساوي صفر بساوي صفر بساوي صفر
+
+461
+00:38:11,480 --> 00:38:20,080
+بساوي صفر بساوي صفر بساوي
+
+462
+00:38:20,080 --> 00:38:24,680
+صفر
+
+463
+00:38:24,680 --> 00:38:25,140
+ب
+
+464
+00:38:29,810 --> 00:38:34,330
+equals 1.2 هذا يعني أن مقاومة المقاومات كلها
+
+465
+00:38:34,330 --> 00:38:41,890
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة
+
+466
+00:38:41,890 --> 00:38:46,910
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة
+
+467
+00:38:46,910 --> 00:38:48,190
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة
+
+468
+00:38:48,190 --> 00:38:51,750
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة
+
+469
+00:38:51,750 --> 00:38:55,570
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة
+
+470
+00:38:55,570 --> 00:39:12,020
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاعندما تقرر
+
+471
+00:39:12,020 --> 00:39:22,060
+الـ X بالمقارنة
+
+472
+00:39:22,060 --> 00:39:23,340
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+473
+00:39:23,340 --> 00:39:25,960
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+474
+00:39:25,960 --> 00:39:27,040
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+475
+00:39:27,040 --> 00:39:27,660
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+476
+00:39:27,660 --> 00:39:33,030
+بالمقارنةأصبح 5% وشركة الشرطة الأولى استمرت في حفظ
+
+477
+00:39:33,030 --> 00:39:39,590
+1.2 مليون دولار 1 مليون 200 ألف دولار في مقاوماتها
+
+478
+00:39:39,590 --> 00:39:41,110
+مقاوماتها مقاوماتها مقاوماتها مقاوماتها مقاوماتها
+
+479
+00:39:41,110 --> 00:39:41,450
+مقاوماتها مقاوماتها مقاوماتها مقاوماتها مقاوماتها
+
+480
+00:39:41,450 --> 00:39:41,890
+مقاوماتها مقاوماتها مقاوماتها مقاوماتها مقاوماتها
+
+481
+00:39:41,890 --> 00:39:42,490
+مقاوماتها مقاوماتها مقاوماتها مقاوماتها مقاوماتها
+
+482
+00:39:42,490 --> 00:39:51,870
+مقاوماتها مقاوماتها مقاوماتها مقاوماتها مقاوماتها
+
+483
+00:39:53,580 --> 00:39:57,480
+هول قدش اندي free reserves 1.2 مليون يعني free
+
+484
+00:39:57,480 --> 00:40:03,580
+reserves اندي one point two one million point two
+
+485
+00:40:03,580 --> 00:40:09,080
+hundred thousand dollars the question is ال X's
+
+486
+00:40:09,080 --> 00:40:12,440
+reserve equals how much this is the question so we
+
+487
+00:40:12,440 --> 00:40:15,920
+have to calculate the required reserve صح؟ and
+
+488
+00:40:15,920 --> 00:40:20,080
+then the X's reserve صح؟ so the required reserve
+
+489
+00:40:20,080 --> 00:40:22,560
+equals five percent
+
+490
+00:40:31,970 --> 00:40:38,830
+400000 400000 400000
+
+491
+00:40:38,830 --> 00:40:45,550
+400000 400000 400000 400000 400000 400000 400000
+
+492
+00:40:45,550 --> 00:40:50,870
+400000 400000 400000 400000 400000 400000 400000
+
+493
+00:40:50,870 --> 00:40:50,990
+400000 400000 400000 400000 400000 400000 400000
+
+494
+00:40:50,990 --> 00:40:54,770
+400000 400000 400000 400000equals the total
+
+495
+00:40:54,770 --> 00:40:58,550
+reserves or reserves minus the required reserves
+
+496
+00:40:58,550 --> 00:41:02,170
+so the total reserves equals how much كداش one
+
+497
+00:41:02,170 --> 00:41:07,110
+million two hundred thousand minus the required
+
+498
+00:41:07,110 --> 00:41:11,790
+reserve so
+
+499
+00:41:11,790 --> 00:41:19,210
+the excess reserve eight hundred thousand dollars
+
+500
+00:41:19,210 --> 00:41:22,550
+right صعب؟
+
+501
+00:41:24,790 --> 00:41:34,230
+لنذهب إلى هذا المثال .. كما ترى .. المقاومات
+
+502
+00:41:34,230 --> 00:41:36,130
+الجديدة .. مقاومات الريكويلد .. ومقاومات الريكويلد
+
+503
+00:41:36,130 --> 00:41:40,550
+.. ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+504
+00:41:40,550 --> 00:41:40,590
+ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+505
+00:41:40,590 --> 00:41:40,770
+ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+506
+00:41:40,770 --> 00:41:41,850
+ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+507
+00:41:41,850 --> 00:41:44,170
+ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+508
+00:41:44,170 --> 00:41:48,170
+ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+509
+00:41:48,170 --> 00:41:53,830
+ومقاومات الريكويلد .. ومقاومإذاً كداش الـ required
+
+510
+00:41:53,830 --> 00:41:58,690
+reserve ratio؟ خمسة في المية، تمام؟ راحوا .. راحوا
+
+511
+00:41:58,690 --> 00:42:02,370
+البنك ماتي loans بقدرش؟ بخمسة وتسعين ألف، تمام؟
+
+512
+00:42:02,370 --> 00:42:06,850
+صح؟ صح راحوا اللي .. اللي أخد ال loan هذا حطه في
+
+513
+00:42:06,850 --> 00:42:12,250
+بنك تاني، in the second bank خمسة وتسعين في المية
+
+514
+00:42:12,250 --> 00:42:17,260
+as a deposit in the second bankالشخص التاني عمل
+
+515
+00:42:17,260 --> 00:42:20,840
+deduction بخمسة في المية بال reserves هذا وصار
+
+516
+00:42:20,840 --> 00:42:24,060
+عنده قداش required reserve هلقدر وصار ميعطى loans
+
+517
+00:42:24,060 --> 00:42:30,440
+هلقدر الشخص التاني الشخص التاني شو عمل؟ أخد هذا
+
+518
+00:42:30,440 --> 00:42:35,080
+المبلغ as a loan وراح حاطهم في بنك تالت هيوم as a
+
+519
+00:42:35,080 --> 00:42:40,770
+depositThe third bank ايش عمل؟ عمل deduction بخمسة
+
+520
+00:42:40,770 --> 00:42:43,650
+في المية قداش خمسة في المية من هذا المبلغ هيوم
+
+521
+00:42:43,650 --> 00:42:47,890
+هلقد وبالتالي بيعمل loan هلقد and so on طيب السؤال
+
+522
+00:42:47,890 --> 00:42:50,630
+بيقولنا let's go to the .. refer to the scenario
+
+523
+00:42:50,630 --> 00:42:54,510
+what is the required reserve ratio لو required
+
+524
+00:42:54,510 --> 00:42:58,990
+reserves over deposits صح؟ طيب what is the money
+
+525
+00:42:58,990 --> 00:43:01,410
+multiplier in this economy let's come back to the
+
+526
+00:43:01,410 --> 00:43:05,590
+money multiplier هلأ الصورة واضحة بالنسبالكم صارت
+
+527
+00:43:05,590 --> 00:43:10,580
+شباب؟بموضوع ال required reserve ratio و ال excess
+
+528
+00:43:10,580 --> 00:43:11,080
+reserves
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/1aY1T9K_Css_raw.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/1aY1T9K_Css_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..7782b89d0ac796a3664a12a8f270b6fff8e83bac
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/1aY1T9K_Css_raw.srt
@@ -0,0 +1,2252 @@
+1
+00:00:21,050 --> 00:00:25,530
+اليوم ان شاء الله سنكمل الحلقة السادسة والتي هي
+
+2
+00:00:25,530 --> 00:00:31,130
+مصادر المال والمحافظة الوطنية في
+
+3
+00:00:31,130 --> 00:00:34,990
+السلاسة السابقة نتكلم عن بعض المصادر والمصادر
+
+4
+00:00:34,990 --> 00:00:38,010
+المالية
+
+5
+00:00:38,010 --> 00:00:44,540
+ومصادر المالالنظام الـ barter الذي تم إصلاحه
+
+6
+00:00:44,540 --> 00:00:57,800
+بإستعمال
+
+7
+00:00:57,800 --> 00:01:02,340
+نظام الـ barter نظام المقيدةوبعد ذلك، كانت فكرة
+
+8
+00:01:02,340 --> 00:01:08,920
+المال تم إصلاح المشكلات المختلفة التي تتعامل مع
+
+9
+00:01:08,920 --> 00:01:14,360
+نظام البرتقال اليوم، إن شاء الله، سنكمل مصطلح
+
+10
+00:01:14,360 --> 00:01:19,580
+المال وسنركز
+
+11
+00:01:19,580 --> 00:01:26,260
+على اتنين أفكار أهمالأدوات الرئيسية التي يستخدمها
+
+12
+00:01:26,260 --> 00:01:33,040
+الحكومة أو الشركة الأمريكية لإصلاح المال أو التحكم
+
+13
+00:01:33,040 --> 00:01:39,740
+في مصادر المال وكيفية تخطيط المزيد من المال ومصادر
+
+14
+00:01:39,740 --> 00:01:43,140
+المال الشركة
+
+15
+00:01:43,140 --> 00:01:46,660
+الأمريكية أو الشركة الأمريكية استخدمت أو استخدمت
+
+16
+00:01:46,660 --> 00:01:50,500
+ثلاث أدوات الرئيسية للتحكم في مصادر المال هذه
+
+17
+00:01:50,500 --> 00:01:56,260
+الأدواتالنسبة للاحتياط القانوني الاحتياط القانوني
+
+18
+00:01:56,260 --> 00:01:59,680
+الاحتياط القانوني الاحتياط القانوني الاحتياط
+
+19
+00:01:59,680 --> 00:02:00,840
+القانوني الاحتياط القانوني الاحتياط القانوني
+
+20
+00:02:00,840 --> 00:02:04,440
+الاحتياط
+
+21
+00:02:04,440 --> 00:02:04,940
+القانوني الاحتياط القانوني الاحتياط القانوني
+
+22
+00:02:04,940 --> 00:02:06,220
+الاحتياط القانوني الاحتياط القانوني الاحتياط
+
+23
+00:02:06,220 --> 00:02:06,280
+القانوني الاحتياط القانوني الاحتياط القانوني
+
+24
+00:02:06,280 --> 00:02:06,280
+الاحتياط القانوني الاحتياط القانوني الاحتياط
+
+25
+00:02:06,280 --> 00:02:06,280
+القانوني الاحتياط القانوني الاحتياط القانوني
+
+26
+00:02:06,280 --> 00:02:06,280
+الاحتياط القانوني الاحتياط القانوني الاحتياط
+
+27
+00:02:06,280 --> 00:02:06,280
+القانوني الاحتياط القانوني الاحتياط قانوني
+
+28
+00:02:06,280 --> 00:02:13,680
+الاحتياط قانوني الاحتياط
+
+29
+00:02:13,680 --> 00:02:21,800
+قانوني الاحتياطمثلًا، إذا كان لديك 100 دولار و كنت
+
+30
+00:02:21,800 --> 00:02:27,380
+تريد أن تضعه كدفع في بنك البلستيني، في هذه الحالة،
+
+31
+00:02:27,380 --> 00:02:32,260
+يجب أن يقوم بنك البلستيني بإختيار أو تقطيع جزء من
+
+32
+00:02:32,260 --> 00:02:35,160
+هذه المادة و يقوم بإختيارها في الشركة الأساسية.
+
+33
+00:02:37,560 --> 00:02:44,290
+قيمة الدفع هو ما يسمى كـ Required Reserve.الجزء
+
+34
+00:02:44,290 --> 00:02:47,990
+هذا اللي بنقصه من المية دولار نحطه في سلطة النقد
+
+35
+00:02:47,990 --> 00:02:53,490
+أو في البنك المركزي اسمه required reserve in order
+
+36
+00:02:53,490 --> 00:02:59,000
+to protect the deposits for the depositorsعشان
+
+37
+00:02:59,000 --> 00:03:03,280
+نحمي اللي هم الإيداعات أو الوذائع تباعت الناس اللي
+
+38
+00:03:03,280 --> 00:03:06,560
+بيحطوا مصاريهم في البنوك تمام؟ طيب، so suppose
+
+39
+00:03:06,560 --> 00:03:09,940
+that the required reserve ratio is the required
+
+40
+00:03:09,940 --> 00:03:15,440
+reserve ratio نسبة الاحتياط القانوني equals twenty
+
+41
+00:03:15,440 --> 00:03:20,940
+percent this means that the Bank of Palestine must
+
+42
+00:03:20,940 --> 00:03:25,040
+deduct twenty percent out of this deposit this is
+
+43
+00:03:25,040 --> 00:03:25,560
+a deposit
+
+44
+00:03:28,220 --> 00:03:34,020
+هي تسمى كتابة مالية 100 دولار في هذه الحالة، يجب
+
+45
+00:03:34,020 --> 00:03:38,880
+أن يقوم البنك بالفلسطينية باستخدام أو تقطيع 20% من
+
+46
+00:03:38,880 --> 00:03:43,480
+100 دولار ويقوم باستخدامه في الشركة الأساسية أو
+
+47
+00:03:43,480 --> 00:03:48,520
+الحكومة المالية البلسطينية، ففي هذه الحالة، مقاومة
+
+48
+00:03:48,520 --> 00:03:53,560
+المالية المطلوبة هي مقاومة المالية المطلوبة مرة
+
+49
+00:03:53,560 --> 00:03:54,900
+مرة مقاومة
+
+50
+00:03:59,390 --> 00:04:03,790
+المستقبل المطلوب يعني
+
+51
+00:04:03,790 --> 00:04:11,070
+كم هي مستقبل المطلوب 20% مرة مرة مرة مرة مرة مرة
+
+52
+00:04:11,070 --> 00:04:11,770
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+53
+00:04:11,770 --> 00:04:12,730
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+54
+00:04:12,730 --> 00:04:12,750
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+55
+00:04:12,750 --> 00:04:15,150
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+56
+00:04:15,150 --> 00:04:16,910
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+57
+00:04:16,910 --> 00:04:16,910
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+58
+00:04:16,910 --> 00:04:16,910
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+59
+00:04:16,910 --> 00:04:22,250
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مequals
+
+60
+00:04:22,250 --> 00:04:26,690
+هذا اللي هو الاحتياط المطلوب يلحق في سلطة النقد
+
+61
+00:04:26,690 --> 00:04:30,190
+equals twenty dollars in this case we have x's
+
+62
+00:04:30,190 --> 00:04:34,050
+reserve by how much eighty dollars يعني احتياط
+
+63
+00:04:34,050 --> 00:04:37,810
+الفقه ده بنقدر نتصرف فيه صح؟ so in this case the
+
+64
+00:04:37,810 --> 00:04:46,310
+x's reserve reserves equals the actual reserve
+
+65
+00:04:46,310 --> 00:04:52,200
+minus the required reserveأو المحافظات المجتمعية
+
+66
+00:04:52,200 --> 00:04:55,880
+المجتمعية
+
+67
+00:04:55,880 --> 00:04:57,280
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+68
+00:04:57,280 --> 00:04:57,860
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+69
+00:04:57,860 --> 00:04:57,920
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+70
+00:04:57,920 --> 00:04:58,780
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+71
+00:04:58,780 --> 00:05:01,900
+المجتمعية
+
+72
+00:05:01,900 --> 00:05:03,380
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+73
+00:05:03,380 --> 00:05:03,380
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+74
+00:05:03,380 --> 00:05:03,380
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+75
+00:05:03,380 --> 00:05:12,200
+المجتمعية المجتمعية المجتمعية المجتمعية المجتمعية
+
+76
+00:05:12,200 --> 00:05:18,060
+المج
+
+77
+00:05:20,490 --> 00:05:25,810
+هو لا يستطيع أن يدفع الانتجار الكام لأنه يجب أن
+
+78
+00:05:25,810 --> 00:05:33,350
+يدفع 20% من هذا الانتجار وانتجاره في البنك أو
+
+79
+00:05:33,350 --> 00:05:37,050
+البنك الرئيسي أو الوظيفة الأمريكية أو الحكومة
+
+80
+00:05:37,050 --> 00:05:39,670
+المالية البلسانية كما تعرف في بلسطين
+
+81
+00:05:44,000 --> 00:05:49,000
+هذا هو أسلحة الأساسية أو أحد الأسلحة أو ثلاث أسلحة
+
+82
+00:05:49,000 --> 00:05:51,060
+التي يمكن استخدامها الشركة الأمريكية أو الوظيفة
+
+83
+00:05:51,060 --> 00:05:54,280
+الأمريكية لتحكم
+
+84
+00:05:54,280 --> 00:05:54,540
+مصادر الدولة الأمريكية لتحكم مصادر الدولة
+
+85
+00:05:54,540 --> 00:05:58,040
+الأمريكية لتحكم مصادر الدولة الأمريكية لتحكم مصادر
+
+86
+00:05:58,040 --> 00:06:01,860
+الدولة الأمريكية لتحكم
+
+87
+00:06:01,860 --> 00:06:01,860
+مصادر الدولة الأمريكية لتحكم مصادر الدولة
+
+88
+00:06:01,860 --> 00:06:01,860
+الأمريكية لتحكم مصادر الدولة الأمريكية لتحكم مصادر
+
+89
+00:06:01,860 --> 00:06:02,080
+الدولة الأمريكية لتحكم مصادر الدولة الأمريكية
+
+90
+00:06:02,080 --> 00:06:08,200
+لتحكم مصادر الدولة الأمريكية لتحكم مصاد
+
+91
+00:06:09,210 --> 00:06:19,470
+إن المقاومة المتطلبة تزداد من 20% إلى 40% هذا يعني
+
+92
+00:06:19,470 --> 00:06:25,130
+ماذا؟ يتقلل المقاومة المتطلبة التي يمكنها البنك أن
+
+93
+00:06:25,130 --> 00:06:31,770
+تدفعها للجمهور او الناس بالضبط ففي هذه الحالة،
+
+94
+00:06:31,770 --> 00:06:37,450
+ستزداد أو تتقل المساعدة المالية؟ بالضبط، ستتقل
+
+95
+00:06:37,450 --> 00:06:41,290
+المساعدة الماليةصح ولا لأ؟ لأنه المسار عمليا صار
+
+96
+00:06:41,290 --> 00:06:43,810
+البنك اللي .. اللي قدر يقرضه من بنك فلسطين للناس
+
+97
+00:06:43,810 --> 00:06:46,930
+جلوة بتالس ال money supply would decline صح ولا
+
+98
+00:06:46,930 --> 00:06:51,090
+لأ؟ so we have an inverse relationship between the
+
+99
+00:06:51,090 --> 00:06:53,850
+required reserve ratio and money supply صح؟
+
+100
+00:06:53,850 --> 00:06:59,810
+exactly هلأ شو هذا معناه؟ انه لو راح البنك او ال
+
+101
+00:06:59,810 --> 00:07:02,190
+central bank او ال federal reserve system جالك انه
+
+102
+00:07:02,190 --> 00:07:05,470
+انا required reserve ratio بدل ما هو 20 بنقص 40
+
+103
+00:07:05,470 --> 00:07:09,310
+ونخليهم عند ال central bankعمليا بيبطل البنوك معاه
+
+104
+00:07:09,310 --> 00:07:11,830
+مصارى أو حجم الوثائع اللى موجودة عند البنوك اللى
+
+105
+00:07:11,830 --> 00:07:14,210
+بتتصرف فيها بتقل و بتقل ال money supply with what؟
+
+106
+00:07:14,210 --> 00:07:18,070
+with decline right؟ so there is an inverse
+
+107
+00:07:18,070 --> 00:07:21,370
+relationship between the required reserve ratio
+
+108
+00:07:21,370 --> 00:07:26,690
+and the money supplyهذا يعني أننا لدينا النتيجة
+
+109
+00:07:26,690 --> 00:07:30,690
+الأخيرة أو النظرية هي أن هناك علاقة عكسية بين
+
+110
+00:07:30,690 --> 00:07:32,370
+مقاومة المال والمقاومة المحتاجة لها ومقاومة المال
+
+111
+00:07:32,370 --> 00:07:33,610
+المحتاجة لها ومقاومة المال المحتاجة لها ومقاومة
+
+112
+00:07:33,610 --> 00:07:36,310
+المال المحتاجة لها ومقاومة المال المحتاجة لها
+
+113
+00:07:36,310 --> 00:07:39,030
+ومقاومة المال المحتاجة لها ومقاومة المال المحتاجة
+
+114
+00:07:39,030 --> 00:07:40,550
+لها ومقاومة المال المحتاجة لها ومقاومة المال
+
+115
+00:07:40,550 --> 00:07:40,550
+المحتاجة لها ومقاومة المال المحتاجة لها ومقاومة
+
+116
+00:07:40,550 --> 00:07:40,870
+المال المحتاجة لها ومقاومة المال المحتاجة لها
+
+117
+00:07:40,870 --> 00:07:48,750
+ومقاومة المال المحتاجة لها ومقاالمدفع الثاني اللي
+
+118
+00:07:48,750 --> 00:07:50,790
+يستطيع استخدامه الشركة الرئيسية أو الشركة الرئيسية
+
+119
+00:07:50,790 --> 00:07:58,690
+هو اتفاق الدفع اتفاق الدفع اتفاق الدفع اتفاق الدفع
+
+120
+00:07:58,690 --> 00:08:04,530
+اتفاق الدفع اتفاق
+
+121
+00:08:04,530 --> 00:08:10,550
+الدفع
+
+122
+00:08:10,550 --> 00:08:16,830
+اتفاق الدفع
+
+123
+00:08:16,870 --> 00:08:24,690
+الدسكاوت ريت دسكاوت ريت
+
+124
+00:08:24,690 --> 00:08:30,190
+دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت
+
+125
+00:08:30,190 --> 00:08:30,190
+ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت
+
+126
+00:08:30,190 --> 00:08:30,250
+دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت
+
+127
+00:08:30,250 --> 00:08:30,250
+ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت
+
+128
+00:08:30,250 --> 00:08:30,250
+دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت
+
+129
+00:08:30,250 --> 00:08:34,650
+ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت دسكاوت ريت
+
+130
+00:08:34,650 --> 00:08:45,530
+دسكاوت ريت دسكاوت ريت دسكاوت روانت ترغب ان تتخلص
+
+131
+00:08:45,530 --> 00:08:49,890
+من دولة او تأخذ دولة من هذه المصرفة انت يجب ان
+
+132
+00:08:49,890 --> 00:08:56,710
+تدفع اهتمامك كمستخدم اذا ذهبت إلى المصرفة التجارية
+
+133
+00:08:56,710 --> 00:09:00,770
+لتدفع دولة في هذه الحالة يجب ان تدفع اهتمامك انت
+
+134
+00:09:00,770 --> 00:09:05,110
+تدفع اهتمامك انت تدفع اهتمامك انت دفع اهتمامك انت
+
+135
+00:09:05,110 --> 00:09:05,350
+دفع اهتمامك انت دفع اهتمامك انت دفع اهتمامك انت
+
+136
+00:09:05,350 --> 00:09:06,650
+دفع اهتمامك انت دفع اهتمامك انت دفع اهتمامك انت
+
+137
+00:09:06,650 --> 00:09:06,650
+دفع اهتمامك انت دفع اهتمامك انت دفع اهتمامك انت
+
+138
+00:09:06,650 --> 00:09:10,510
+دفع اهتمام
+
+139
+00:09:11,240 --> 00:09:18,420
+أو اذا كان لديه إفلاس إذا كان بحاجة إلى المال أو
+
+140
+00:09:18,420 --> 00:09:24,720
+إذا كان بحاجة إلى المال من مركز التجارب يمكنه
+
+141
+00:09:24,720 --> 00:09:32,120
+الذهاب إلى مركز التجارب لإستغلال المال الوحيد اللي
+
+142
+00:09:32,120 --> 00:09:35,880
+كمان البنك التجارب يروح يقترض من من؟ من سلطة النقد
+
+143
+00:09:35,880 --> 00:09:40,810
+أو من البنك المركزيThey have to pay a discount
+
+144
+00:09:40,810 --> 00:09:43,550
+it's called or the cost of borrowing تكلفة
+
+145
+00:09:43,550 --> 00:09:45,830
+الاقتراض هذه من البنك التجاري from the central
+
+146
+00:09:45,830 --> 00:09:49,010
+bank is called the discount rate لأن هم بيدفعوا
+
+147
+00:09:49,010 --> 00:09:54,190
+interest كمان صح ال central bank باعترش الفلوس هيك
+
+148
+00:09:54,190 --> 00:09:57,690
+so we have what a discount rate the cost of
+
+149
+00:09:57,690 --> 00:10:00,470
+borrowing for the commercial banks from the
+
+150
+00:10:00,470 --> 00:10:02,630
+central bank or the federal reserve system is
+
+151
+00:10:02,630 --> 00:10:08,050
+called the discount rate سعر خصم تمام so suppose
+
+152
+00:10:08,050 --> 00:10:16,250
+thatأو سؤالي هو ماهي علاقة بين رقم التسكيب والمال
+
+153
+00:10:16,250 --> 00:10:24,770
+المستخدم؟ إذا رقم التسكيب أزداد
+
+154
+00:10:24,770 --> 00:10:29,290
+تسكيب المال المستخدم يعني سبوز أنه البنك المركزي
+
+155
+00:10:29,290 --> 00:10:33,210
+يقول لك والله أنا بدل بدأ أخد على السحبات بعتك
+
+156
+00:10:33,210 --> 00:10:36,350
+كبنك تجاري إذا بدأ أخد بدل ما أخد تلاتين في المية
+
+157
+00:10:36,350 --> 00:10:40,130
+بدي أخد سبعين في الميةتمام؟ و بيبطلوا .. بيبطلوا
+
+158
+00:10:40,130 --> 00:10:42,370
+البنوك التجارية تقترض منهم، مظبوط ولا لأ؟ و ابتدال
+
+159
+00:10:42,370 --> 00:10:45,250
+ال money supply هو what؟ هو ال decline، مظبوط ولا
+
+160
+00:10:45,250 --> 00:10:47,630
+لأ؟ لأن ال money supply هو الجزء منه هو اللي موجود
+
+161
+00:10:47,630 --> 00:10:52,130
+في ال .. ال commercial banks، صح شباب؟ So, there
+
+162
+00:10:52,130 --> 00:10:54,490
+is an inverse relationship between the discount
+
+163
+00:10:54,490 --> 00:10:56,310
+rate and money supply, yes
+
+164
+00:10:59,350 --> 00:11:06,010
+القيمة التي ذكرتها هي قيمة الانتجار من الشركات
+
+165
+00:11:06,010 --> 00:11:09,950
+التقليدية من الشركة التقليدية، إذا كان الشركة
+
+166
+00:11:09,950 --> 00:11:15,630
+التقليدية بحاجة إلى المال و ذهبت إلى الشركة
+
+167
+00:11:15,630 --> 00:11:21,040
+التقليدية لتلقى دفعةهو يجب أن يدفع اهتمام ما يدفع
+
+168
+00:11:21,040 --> 00:11:25,200
+اهتمام هذا الاهتمام يسمى بـ Discount Rate اعتبر ان
+
+169
+00:11:25,200 --> 00:11:28,060
+الشركة الأساسية قررت ان تزيد اهتمام الـDiscount
+
+170
+00:11:28,060 --> 00:11:32,640
+Rate بيقولهم ان سعر الاقتراض عالي بديش اخليه 20%
+
+171
+00:11:32,640 --> 00:11:35,420
+بدي اخليه 60% و بدي اخليه 50% في هذه الحالة ماذا
+
+172
+00:11:35,420 --> 00:11:40,320
+سيحدث؟ مصادر المال اللي متوفر في مصادر الشركات
+
+173
+00:11:40,320 --> 00:11:43,540
+التقليدية لتحفزها في هذه الحالة ماذا سيحدث؟
+
+174
+00:11:43,540 --> 00:11:46,120
+ستتخلص. لذلك مصادر المال بالعام ستتخلص
+
+175
+00:11:50,380 --> 00:11:54,840
+النهاية، لدينا علاقة عادية بين عدد المساعدة
+
+176
+00:11:54,840 --> 00:11:58,420
+والمساعدة والمساعدة والمساعدة والمساعدة والمساعدة
+
+177
+00:11:58,420 --> 00:12:04,680
+والمساعدة والمساعدة والمساعدة
+
+178
+00:12:04,680 --> 00:12:07,600
+والمساعدة والمساعدة
+
+179
+00:12:13,460 --> 00:12:17,060
+القاعدة تبعتنا هي القاعدة تبعتنا في انفرس
+
+180
+00:12:17,060 --> 00:12:21,080
+relationship between record ratio and money supply
+
+181
+00:12:21,080 --> 00:12:24,200
+as well as انفرس relationship between the discount
+
+182
+00:12:24,200 --> 00:12:26,860
+rate and money supply what about the last point
+
+183
+00:12:26,860 --> 00:12:29,340
+which is or the last tool that the central bank
+
+184
+00:12:29,340 --> 00:12:33,260
+can use or uses in order to control the money
+
+185
+00:12:33,260 --> 00:12:37,850
+supply the last point isالعملات في السوق المفتوحة
+
+186
+00:12:37,850 --> 00:12:41,470
+في السوق المفتوحة فهذه هي الأولى هذه هي الطريقة
+
+187
+00:12:41,470 --> 00:12:45,590
+الثانية الطريقة الثالثة هي العملات في السوق
+
+188
+00:12:45,590 --> 00:12:49,010
+المفتوحة في السوق المفتوحة
+
+189
+00:13:05,410 --> 00:13:10,530
+of bonds عادي لو انه suppose that ال central bank
+
+190
+00:13:10,530 --> 00:13:16,390
+would like to increase the money supply بيشتر
+
+191
+00:13:16,390 --> 00:13:20,710
+ورق و بيعطيهم مصاريبيشتري securities و bonds و هيك
+
+192
+00:13:20,710 --> 00:13:25,190
+و بيعطيهم مصارى، so in this case if the central
+
+193
+00:13:25,190 --> 00:13:28,910
+bank would like to increase the money supply بيزود
+
+194
+00:13:28,910 --> 00:13:31,050
+المصارى في دنيا الناس مش بيعمل، بيشتري منهم الورق
+
+195
+00:13:31,050 --> 00:13:35,670
+اللي موجود معاهم، so in this case it can purchase
+
+196
+00:13:35,670 --> 00:13:42,450
+or buySecurities or bonds and so on صح؟ and if you
+
+197
+00:13:42,450 --> 00:13:45,450
+.. if the banks or the central bank would like to
+
+198
+00:13:45,450 --> 00:13:47,950
+decrease the money supply بدي أسحب المسار من دين
+
+199
+00:13:47,950 --> 00:13:52,130
+الناس إيش ببيعهم؟ بعطيهم ورق و باخد مساري so in
+
+200
+00:13:52,130 --> 00:13:56,170
+this case it can what? sell securities or bonds
+
+201
+00:13:56,170 --> 00:14:02,430
+treasure bonds and notes تمام؟ صعب؟ بس يعني ببيعهم
+
+202
+00:14:02,430 --> 00:14:04,830
+ورق و باخد منهم الفلوس و بتاع ليه in this case the
+
+203
+00:14:04,830 --> 00:14:08,770
+money supply would decline right؟الان دعونا نذهب
+
+204
+00:14:08,770 --> 00:14:14,790
+إلى مجالات مختلفة أو مجالات مرتبطة بالمقاومة
+
+205
+00:14:14,790 --> 00:14:21,230
+والمقاومة المتطلبة ومشكلة مختلفة مرتبطة بالمال
+
+206
+00:14:21,230 --> 00:14:24,350
+المستعمر لذلك كما ترى المقاومة
+
+207
+00:14:27,420 --> 00:14:31,100
+means the total reserves are what the deposit that
+
+208
+00:14:31,100 --> 00:14:35,020
+the bank has at the federal reserve a reserve bank
+
+209
+00:14:35,020 --> 00:14:38,440
+plus it cashed on hand the required reserve ratio
+
+210
+00:14:38,440 --> 00:14:42,720
+اللي هو هذا نسبة الاحتياط القانوني what is it is
+
+211
+00:14:42,720 --> 00:14:45,880
+the percentage of its total deposits that the
+
+212
+00:14:45,880 --> 00:14:49,000
+banks must keep as a reserves at the federal
+
+213
+00:14:49,000 --> 00:14:52,620
+reserve system اللي وضحناه تمام؟ طيب
+
+214
+00:14:58,590 --> 00:15:04,990
+الخطوات المتوفرة هي او اقل الخطوات الحقيقية او اقل
+
+215
+00:15:04,990 --> 00:15:13,690
+الخطوات المتوفرة او اقل الخطوات المتوفرة او اقل
+
+216
+00:15:13,690 --> 00:15:18,370
+الخطوات المتوفرة او اقل الخطوات
+
+217
+00:15:18,370 --> 00:15:27,270
+المتوفرة او اقل
+
+218
+00:15:27,270 --> 00:15:36,970
+الخطوات المتوفرةطيب .. اعتبر .. لنذهب
+
+219
+00:15:36,970 --> 00:15:44,010
+لهذا المثال أو التعليم .. كما ترى .. إذا كانت
+
+220
+00:15:44,010 --> 00:15:53,150
+المقاومة المطلوبة هي 20 شخص .. فالبنك لديه مقاومة
+
+221
+00:15:53,150 --> 00:15:59,800
+مقاومة ماذا؟ 80 دولارمع 80 دولار اكتشف مقاومة 100
+
+222
+00:15:59,800 --> 00:16:06,200
+دولار اكتشف مقاومة 100 دولار اكتشف مقاومة 100
+
+223
+00:16:06,200 --> 00:16:10,260
+دولار اكتشف مقاومة 100 دولار اكتشف مقاومة 100
+
+224
+00:16:10,260 --> 00:16:12,500
+دولار اكتشف مقاومة 100 دولار اكتشف مقاومة 100
+
+225
+00:16:12,500 --> 00:16:17,160
+دولار اكتشف مقاومة 100 دولار اكتشف
+
+226
+00:16:17,160 --> 00:16:19,660
+مقاومة 100 دولار اكتشف مقاومة 100 دولار اكتشف
+
+227
+00:16:19,660 --> 00:16:19,800
+مقاومة 100 دولار اكتشف مقاومة 100 دولار اكتشف
+
+228
+00:16:19,800 --> 00:16:22,160
+مقاومة 100 دولار اكتشف مقاومة 100 دولار اكتشف
+
+229
+00:16:22,160 --> 00:16:27,460
+مقاومة 100 دولار اكتشف مقاequals twenty person
+
+230
+00:16:27,460 --> 00:16:31,660
+times five hundred كده اندي reserves one hundred
+
+231
+00:16:31,660 --> 00:16:34,920
+هذا required reserve كله مظبوط وفي اندي loans كده
+
+232
+00:16:34,920 --> 00:16:38,760
+اش بقدر اعمل four hundred خلي بقدر اروح على اشي
+
+233
+00:16:38,760 --> 00:16:48,200
+اوضح ادحن
+
+234
+00:16:48,200 --> 00:16:49,140
+رجعله هال gate
+
+235
+00:16:57,970 --> 00:17:16,530
+لأ كله رجال له هذا عشان الله نفسي Now
+
+236
+00:17:16,530 --> 00:17:22,690
+suppose that we have the following example The
+
+237
+00:17:22,690 --> 00:17:26,150
+first charter bank has assets and liabilities
+
+238
+00:17:27,730 --> 00:17:31,050
+الليابيتيز .. نحن لدينا ديبوزيت نت وورث و
+
+239
+00:17:31,050 --> 00:17:36,490
+الليابيتيز عامة .. لذا كما ترى ديبوزيت يعني كم؟
+
+240
+00:17:36,490 --> 00:17:42,570
+800، صحيح؟ نت وورث يعني 400، هدول اللي بقدر يتصرف،
+
+241
+00:17:42,570 --> 00:17:45,690
+اللي مقدرش يتصرف فيهم البنك، خلينا نشوف، لنذهب
+
+242
+00:17:45,690 --> 00:17:50,790
+للتعاملاتاستخدام الاسم الموجود في الاسم الموجود في
+
+243
+00:17:50,790 --> 00:17:51,730
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+244
+00:17:51,730 --> 00:17:55,410
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+245
+00:17:55,410 --> 00:17:59,010
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+246
+00:17:59,010 --> 00:17:59,030
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+247
+00:17:59,030 --> 00:17:59,790
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+248
+00:17:59,790 --> 00:18:03,170
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+249
+00:18:03,170 --> 00:18:03,470
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+250
+00:18:03,470 --> 00:18:05,330
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+251
+00:18:05,330 --> 00:18:07,090
+الاسم الموجود في الاسم الموجود في الاسم الموجود في
+
+252
+00:18:07,090 --> 00:18:12,910
+الاسم الموجود في الاسم الموجود في الاس
+
+253
+00:18:14,610 --> 00:18:19,370
+اللي ا suppose انه ال deposit equal كدهش؟ 800 و
+
+254
+00:18:19,370 --> 00:18:23,870
+عند ال required reserve ratio كدهش؟ 25% كدهش بيكون
+
+255
+00:18:23,870 --> 00:18:29,410
+فيه عند ال reserves؟ 865% exactly so the reserves
+
+256
+00:18:29,410 --> 00:18:34,690
+in this
+
+257
+00:18:34,690 --> 00:18:36,750
+case the reserves equals
+
+258
+00:18:44,280 --> 00:18:51,240
+equals deposit times the required reserve ratio
+
+259
+00:18:51,240 --> 00:18:55,580
+طبعا هذا when x is reserved بيساوى صفر لأنه بيقول
+
+260
+00:18:55,580 --> 00:18:58,240
+ليه مافيش عند x is reserves وبالتالي ال reserves
+
+261
+00:18:58,240 --> 00:19:00,700
+كله إيش بيساوي بيساوي required reserve يعني بترجع
+
+262
+00:19:00,700 --> 00:19:03,680
+للسؤال هيك شو شباب؟
+
+263
+00:19:06,330 --> 00:19:10,710
+هذا بيقولنا و انه ايش انه if the first chartered
+
+264
+00:19:10,710 --> 00:19:14,070
+bank is meeting its reserves requirements and has
+
+265
+00:19:14,070 --> 00:19:17,590
+no excess reserves لما بيكون فيش اندي excess
+
+266
+00:19:17,590 --> 00:19:20,790
+reserves يعني excess reserves equals قداش Zero
+
+267
+00:19:20,790 --> 00:19:23,650
+يعني ال reserves في هذا الحالة ان ال reserves كله
+
+268
+00:19:23,650 --> 00:19:28,030
+ايش بيسوي لأ لابد ارجع لل law طبعا لل formula
+
+269
+00:19:28,030 --> 00:19:30,710
+reserves كله total reserves هذا لما بحكي في
+
+270
+00:19:30,710 --> 00:19:36,160
+reserves بحكي في total reserves equalsالـ Required
+
+271
+00:19:36,160 --> 00:19:39,280
+Reserves plus ال Excess Reserves
+
+272
+00:19:47,090 --> 00:19:51,470
+X's هل هو قولي انه if the X's reserves equals 0
+
+273
+00:19:51,470 --> 00:19:54,190
+معناه الكلام انه ال total reserves اللي هو ال
+
+274
+00:19:54,190 --> 00:19:57,710
+reserves هذا بيساوي ال quadreserves صح؟ هي السؤال
+
+275
+00:19:57,710 --> 00:20:01,290
+هيك so let's come back to the question لما يعطينا
+
+276
+00:20:01,290 --> 00:20:05,410
+that quadreserve ratio is 25% إذا كان ال X's
+
+277
+00:20:05,410 --> 00:20:10,150
+reserves يساوي صفر قداش في عندى the question is
+
+278
+00:20:10,150 --> 00:20:15,810
+its reserves قداش اللي هو عمليا reserves هذا قداش
+
+279
+00:20:15,810 --> 00:20:21,270
+بيساويit equals deposits times times required
+
+280
+00:20:21,270 --> 00:20:25,370
+reserve ratio لأنه ال reserves هو يساوي required
+
+281
+00:20:25,370 --> 00:20:30,430
+reserves في هذه الحالة لأن هذا صفر صح؟ so it
+
+282
+00:20:30,430 --> 00:20:37,710
+equals eight hundred dollars times zero point
+
+283
+00:20:37,710 --> 00:20:40,670
+twenty five كدهش هذا بيكون؟
+
+284
+00:20:43,260 --> 00:20:46,760
+So in this case the reserves equals 200 اللي في ال
+
+285
+00:20:46,760 --> 00:20:49,440
+exercise اللي جاي هتوضح الصورة بشكل أوضح بس لإنه
+
+286
+00:20:49,440 --> 00:20:55,020
+هذا the first example طب ال loans قدش بيخطط اللي
+
+287
+00:20:55,020 --> 00:20:57,660
+ال total ال total لازم ال liabilities equals
+
+288
+00:20:57,660 --> 00:21:01,260
+assets لازم ال assets تساوي ال liabilities
+
+289
+00:21:01,260 --> 00:21:07,920
+وبالتالي ال total must equal 1200 إذا قدش فيه in
+
+290
+00:21:07,920 --> 00:21:11,160
+the loans بيقدر يعطيه؟ 1000
+
+291
+00:21:14,100 --> 00:21:21,220
+صح؟ تمام؟ طيب so the question is how much is the
+
+292
+00:21:21,220 --> 00:21:27,820
+reserve? 200 و ال total assets equals one hundred
+
+293
+00:21:27,820 --> 00:21:29,000
+.. تمام؟
+
+294
+00:21:31,360 --> 00:21:35,720
+اللي بعد هو بيقولنا انه its loans equals how much
+
+295
+00:21:35,720 --> 00:21:40,400
+one thousand بعدين اللي هو ال total assets one
+
+296
+00:21:40,400 --> 00:21:43,460
+thousand two hundred طب let's go to this example
+
+297
+00:21:43,460 --> 00:21:49,480
+the
+
+298
+00:21:49,480 --> 00:21:53,740
+first commercial bank has the following assets and
+
+299
+00:21:53,740 --> 00:21:56,580
+liabilities right the information about the
+
+300
+00:21:56,580 --> 00:22:02,270
+liabilities are givenThe total assets equals the
+
+301
+00:22:02,270 --> 00:22:07,630
+total liabilities, right؟ طيب As
+
+302
+00:22:07,630 --> 00:22:10,930
+you see, the total reserves equals how much؟
+
+303
+00:22:10,930 --> 00:22:15,550
+800000$، صح؟ كدهش في عندنا required reserve؟ 200
+
+304
+00:22:15,550 --> 00:22:24,030
+كدهش ال excess reserve؟ Exactly، متممتها 600000$،
+
+305
+00:22:24,030 --> 00:22:31,180
+صح؟ كدهش في عندى loans، إذن؟ اللي هو2 مليون و نص 2
+
+306
+00:22:31,180 --> 00:22:37,600
+.5 مليون minus ال reserves صحش بقى؟ أثبت ولا لأ؟
+
+307
+00:22:37,600 --> 00:22:42,860
+مين مش فاهم طيب ال total assets عبارة عن إيش ال
+
+308
+00:22:42,860 --> 00:22:48,060
+reserves plus ال loans صح؟ وبالتالي ال total أو ال
+
+309
+00:22:48,060 --> 00:22:51,180
+loans بيساوي 2 مليون و نص ناقص 800 ألف جدش بيكون
+
+310
+00:22:51,180 --> 00:23:04,670
+مليون و سبعمية ألف 1.7 خلاص مليونأو هذا
+
+311
+00:23:04,670 --> 00:23:10,390
+كل شيء تمام؟ طيب، فالسؤال هو تفضل للأسفل، أولاً،
+
+312
+00:23:10,390 --> 00:23:17,510
+كمية محافظة X كمية محافظة X هو كم؟ تمام، ورقم
+
+313
+00:23:17,510 --> 00:23:21,650
+محافظة محافظة محافظة محافظة محافظة محافظة محافظة
+
+314
+00:23:21,650 --> 00:23:22,430
+محافظة محافظة محافظة محافظة محافظة محافظة محافظة
+
+315
+00:23:22,430 --> 00:23:24,870
+محافظة محافظة محافظة محافظة محافظة محافظة محافظة
+
+316
+00:23:24,870 --> 00:23:25,970
+محافظة محافظة محافظة محافظة محافظة محافظة محافظة
+
+317
+00:23:25,970 --> 00:23:28,930
+محافظة محافظة محافظة محافظة مSo، كدهش الـ Required
+
+318
+00:23:28,930 --> 00:23:36,810
+Reserve Ratio؟ Required Reserve Ratio equals
+
+319
+00:23:36,810 --> 00:23:41,570
+Required
+
+320
+00:23:41,570 --> 00:23:48,070
+Reserves over Deposits طبعا
+
+321
+00:23:48,070 --> 00:23:48,830
+مضروب في 100%
+
+322
+00:23:54,120 --> 00:23:58,520
+بالنسبة لهذه الحالة دعونا نعود إلى المعلومات كما
+
+323
+00:23:58,520 --> 00:24:01,520
+ترى مقارنة المقارنة المطلوبة بالمقارنة المطلوبة
+
+324
+00:24:01,520 --> 00:24:05,660
+بالمقارنة المطلوبة بالمقارنة المطلوبة بالمقارنة
+
+325
+00:24:05,660 --> 00:24:05,780
+المطلوبة المطلوبة المطلوبة المطلوبة المطلوبة
+
+326
+00:24:05,780 --> 00:24:08,060
+المطلوبة المطلوبة المطلوبة المطلوبة المطلوبة
+
+327
+00:24:08,060 --> 00:24:09,640
+المطلوبة المطلوبة المطلوبة المطلوبة المطلوبة
+
+328
+00:24:09,640 --> 00:24:13,800
+المطلوبة المطلوبة المطلوبة
+
+329
+00:24:13,800 --> 00:24:13,800
+المطلوبة المطلوبة المطلوبة المطلوبة المطلوبة
+
+330
+00:24:13,800 --> 00:24:19,860
+المطلوبة المطلوبة المطلوبة المطلوبة المطلوبة
+
+331
+00:24:19,860 --> 00:24:21,500
+المطل
+
+332
+00:24:23,980 --> 00:24:29,000
+x100 وبالتالي هذا بيساوي عشرة في المية that's it
+
+333
+00:24:29,000 --> 00:24:36,180
+تمام okay مين
+
+334
+00:24:36,180 --> 00:24:41,360
+مش فاهم طيب اعيد لون اه شباب حبابي مين اعيد لون
+
+335
+00:24:41,360 --> 00:24:46,440
+okay okay
+
+336
+00:24:46,440 --> 00:24:50,060
+the first commercial bank total loans equals قداش
+
+337
+00:24:50,060 --> 00:24:57,770
+how muchحسبناها one million seven hundred thousand
+
+338
+00:24:57,770 --> 00:25:02,150
+dollars the
+
+339
+00:25:02,150 --> 00:25:06,130
+last دي the answer is دي okay let's go to this
+
+340
+00:25:06,130 --> 00:25:14,210
+example طبعا
+
+341
+00:25:14,210 --> 00:25:17,450
+هذا أجى بالامتحان ال .. بال final exam المرة
+
+342
+00:25:17,450 --> 00:25:23,760
+الماضيةكما ترى لدينا مصالح او مصالح المساواة مصالح
+
+343
+00:25:23,760 --> 00:25:26,260
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+344
+00:25:26,260 --> 00:25:29,260
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+345
+00:25:29,260 --> 00:25:30,620
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+346
+00:25:30,620 --> 00:25:30,640
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+347
+00:25:30,640 --> 00:25:32,220
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+348
+00:25:32,220 --> 00:25:36,120
+مصالح مصالح مصالح مصالح مصالح مصالح مصالح مصالح
+
+349
+00:25:36,120 --> 00:25:41,660
+مصالح م
+
+350
+00:25:47,840 --> 00:25:54,920
+دفع خمس عشر ألف دولار، كم هو مجموعه؟ ثلاث
+
+351
+00:25:54,920 --> 00:26:00,080
+عشر ألف دولار، كم هو مجموعه؟ ثلاث عشر ألف دولار،
+
+352
+00:26:00,080 --> 00:26:07,140
+كم هو مجموعه؟ ثلاث عشر ألف دولار، كم هو مجموعه؟
+
+353
+00:26:10,110 --> 00:26:15,910
+exactly 500000$ thank you تمام طيب so how much is
+
+354
+00:26:15,910 --> 00:26:19,310
+the required reserve ratio the required reserve
+
+355
+00:26:19,310 --> 00:26:23,030
+ratio equals the required reserve over deposits
+
+356
+00:26:23,030 --> 00:26:33,430
+قداش 100100000 over 500$ قداش 20%مظبوط twenty
+
+357
+00:26:33,430 --> 00:26:37,110
+percent so the required reserve equals twenty
+
+358
+00:26:37,110 --> 00:26:41,810
+percent what else ال excess reserve equals how
+
+359
+00:26:41,810 --> 00:26:45,530
+much exactly two hundred it's already calculated
+
+360
+00:26:45,530 --> 00:26:50,050
+هيها ال loans five hundred و ال net worth three
+
+361
+00:26:50,050 --> 00:26:58,610
+hundred these are the questions طيب crescent اه
+
+362
+00:26:58,610 --> 00:27:00,950
+هذا another question
+
+363
+00:27:07,320 --> 00:27:12,600
+Crescent City Bank لديها 2 مليون دفعات، فالدفع يقل
+
+364
+00:27:12,600 --> 00:27:19,960
+كم؟ 2 مليون، فالدفع يقل
+
+365
+00:27:19,960 --> 00:27:22,100
+200 مليون
+
+366
+00:27:26,190 --> 00:27:29,210
+Crescent City Bank is meeting its reserve
+
+367
+00:27:29,210 --> 00:27:33,430
+requirement and has no excess reserves. This means
+
+368
+00:27:33,430 --> 00:27:37,230
+ان ال excess reserves equals كداش؟ Zero. So عند ال
+
+369
+00:27:37,230 --> 00:27:44,370
+excess reserves equals zero. Or this means ان ال
+
+370
+00:27:44,370 --> 00:27:49,910
+reserves كله equals required reserve. شايف معناه؟
+
+371
+00:27:51,100 --> 00:27:54,020
+بسبب ان الاختصارات المحتاجة او الاختصارات المحتاجة
+
+372
+00:27:54,020 --> 00:27:56,920
+او الاختصارات المحتاجة او الاختصارات المحتاجة او
+
+373
+00:27:56,920 --> 00:28:00,840
+الاختصارات المحتاجة او الاختصارات المحتاجة او
+
+374
+00:28:00,840 --> 00:28:07,100
+الاختصارات المحتاجة او الاختصارات
+
+375
+00:28:07,100 --> 00:28:16,110
+المحتاجةطيب، لنعود إلى التعليم، لديه 40 مليون في
+
+376
+00:28:16,110 --> 00:28:19,210
+محافظات، يعني عند الـ required reserves أو
+
+377
+00:28:19,210 --> 00:28:27,050
+محافظات، كداش؟ 40، لذا، محافظات أو محافظات محتاجة
+
+378
+00:28:27,050 --> 00:28:32,210
+تقريبا 40 مليون، صحيح؟ مركز أو محافظة أو محافظة
+
+379
+00:28:32,210 --> 00:28:38,620
+تقريبا كداش؟ 30%exactly مظبوط so the required
+
+380
+00:28:38,620 --> 00:28:44,320
+reserve ratio equals the required reserves over
+
+381
+00:28:44,320 --> 00:28:48,440
+deposits equals
+
+382
+00:28:48,440 --> 00:28:53,400
+four hundred over two hundred كدهش بيطلع هذا
+
+383
+00:28:53,400 --> 00:29:01,680
+twenty percent that's it صعب ايه طب مين مش فاهم
+
+384
+00:29:01,680 --> 00:29:11,650
+ايدلهطيب لنذهب لهذا المثال ناريان ناشنال بنك لديه
+
+385
+00:29:11,650 --> 00:29:17,230
+750 دولار او مليون دولار في المقاومات لذا مقاومة
+
+386
+00:29:17,230 --> 00:29:27,790
+كم؟ مقاومة 750
+
+387
+00:29:27,790 --> 00:29:35,090
+مليون دولارالمقاومة المطلوبة هي 30% المقاومة
+
+388
+00:29:35,090 --> 00:29:41,750
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+389
+00:29:41,750 --> 00:29:44,190
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+390
+00:29:44,190 --> 00:29:45,190
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+391
+00:29:45,190 --> 00:29:46,410
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+392
+00:29:46,410 --> 00:29:48,070
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+393
+00:29:48,070 --> 00:29:49,110
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+394
+00:29:49,110 --> 00:29:49,710
+المطلوبة هي 30% المقاومة المطلوبة هي 30% المقاومة
+
+395
+00:29:49,710 --> 00:29:57,810
+المطلوبة هي 30% المقاومة المطلوبة هي 30
+
+396
+00:29:57,810 --> 00:30:10,250
+% المق0.30 x 750 equals 225 مليون دولار this is
+
+397
+00:30:10,250 --> 00:30:17,950
+the required reserve ratio طيب كده يكون عندهم اللي
+
+398
+00:30:17,950 --> 00:30:23,950
+هو ال X is reserve in this case 750 minus 250
+
+399
+00:30:23,950 --> 00:30:27,610
+exactly اللي هو ال X is reserve in this case مجلدش
+
+400
+00:30:27,610 --> 00:30:33,150
+انه يسوى صفر equals zeroالخطوة التالية هي خطوة
+
+401
+00:30:33,150 --> 00:30:34,110
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+402
+00:30:34,110 --> 00:30:39,290
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+403
+00:30:39,290 --> 00:30:44,150
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+404
+00:30:44,150 --> 00:30:44,970
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+405
+00:30:44,970 --> 00:30:44,970
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+406
+00:30:44,970 --> 00:30:44,970
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+407
+00:30:44,970 --> 00:30:44,970
+الاستخدام الاستخدم الاستخدم الاستخدم الاستخدم
+
+408
+00:30:44,970 --> 00:30:45,230
+الاستخدم الاستخدم الاستخدم الاستخدم الاستخدم
+
+409
+00:30:45,230 --> 00:30:52,190
+الاستخدم الاستخدم
+
+410
+00:30:52,190 --> 00:31:00,200
+الاانترا كوستال بانك لديه 5 مليون ديبوزيت و 500
+
+411
+00:31:00,200 --> 00:31:05,420
+ألف محافظة خليني
+
+412
+00:31:05,420 --> 00:31:10,780
+نشوف نعمل تجزئة للبيانات و نشوف شو الحقيقه فالسؤال
+
+413
+00:31:10,780 --> 00:31:20,800
+هو اذا ان الديبوزيت ايه كم؟ ديبوزيت
+
+414
+00:31:23,280 --> 00:31:39,260
+equals 500000$ 500000
+
+415
+00:31:39,260 --> 00:31:47,780
+$ in reserves 500000
+
+416
+00:31:47,780 --> 00:32:06,000
+$إذا كانت مقاومة الـ RRR مقاومة 5% إذا
+
+417
+00:32:06,000 --> 00:32:15,300
+كانت مقاومة الـ
+
+418
+00:32:15,300 --> 00:32:18,680
+RRR مقاومة 5% إذا كانت مقاومة الـ RRR مقاومة 5%
+
+419
+00:32:18,680 --> 00:32:18,680
+إذا كانت مقاومة الـ RRR مقاومة 5%
+
+420
+00:32:22,880 --> 00:32:27,240
+الأموال المطلوبة مطلوبة مطلوبة مطلوبة مطلوبة
+
+421
+00:32:27,240 --> 00:32:29,820
+مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة
+
+422
+00:32:29,820 --> 00:32:34,600
+مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة
+
+423
+00:32:34,600 --> 00:32:34,600
+مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة
+
+424
+00:32:34,600 --> 00:32:34,980
+مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة
+
+425
+00:32:34,980 --> 00:32:35,040
+مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة مطلوبة
+
+426
+00:32:35,040 --> 00:32:39,940
+مطلوبة مطلوبة مطلوبة مطلوب
+
+427
+00:32:42,860 --> 00:32:46,500
+هنا إيش؟ this is the required reserve طب قديش ال
+
+428
+00:32:46,500 --> 00:32:49,780
+excess reserve? how much is the excess reserve?
+
+429
+00:32:50,160 --> 00:32:54,320
+exactly total reserves minus the required reserves
+
+430
+00:32:54,320 --> 00:33:01,160
+so the excess reserve equals
+
+431
+00:33:01,160 --> 00:33:08,860
+the total reserves or reserves minus the required
+
+432
+00:33:08,860 --> 00:33:14,470
+reservesصح؟ so equals five hundred thousand
+
+433
+00:33:14,470 --> 00:33:18,110
+dollars minus two hundred fifty thousand dollars
+
+434
+00:33:18,110 --> 00:33:23,390
+equals two hundred fifty thousand dollars that's
+
+435
+00:33:23,390 --> 00:33:31,770
+it صعب الأمور؟ ده ده ده طيب let's go to another
+
+436
+00:33:31,770 --> 00:33:41,800
+questionالبنك في أسيا لديه نفس الشيء أعتقد دبوزيت
+
+437
+00:33:41,800 --> 00:33:49,260
+980 ألف محافظة و 9 مليون دبوزيت و مقارنة المحافظة
+
+438
+00:33:49,260 --> 00:33:51,340
+الواحدة 10% كمية محافظة ال X
+
+439
+00:33:56,780 --> 00:34:04,840
+حسنًا، مصدر Red Oak لديه 2 مليون دفعات و 400 ألف
+
+440
+00:34:04,840 --> 00:34:11,300
+محافظة إذا كانت محافظة الـ X هي 800 ألف دولار، كم
+
+441
+00:34:11,300 --> 00:34:19,480
+هي محافظة الريكويد؟ دعنا نجزء البيانات، كما ترى،
+
+442
+00:34:19,480 --> 00:34:31,950
+المحافظة هي كميةمدفعات كم؟ 2 مليون 400000
+
+443
+00:34:31,950 --> 00:34:38,130
+$ 400000
+
+444
+00:34:38,130 --> 00:34:52,350
+$ وإذا مقاومة X مقاومة X مقاومة X مقاومة X مقاومة
+
+445
+00:34:52,350 --> 00:34:58,090
+X 100000$ماذا يعني عدد عدد المحافظة المطلوبة؟ يجب
+
+446
+00:34:58,090 --> 00:35:00,570
+أن نتكلم عن عدد المحافظة المطلوبة ومن ثم عدد
+
+447
+00:35:00,570 --> 00:35:11,710
+المحافظة المطلوبة
+
+448
+00:35:14,550 --> 00:35:17,530
+because total reserves لما بيقولي reserves على طول
+
+449
+00:35:17,530 --> 00:35:20,870
+بيعرف بفهم انه بيحكي عن total reserves تمام؟ so
+
+450
+00:35:20,870 --> 00:35:25,270
+reserves انت كدهش؟ four hundred thousand dollars
+
+451
+00:35:25,270 --> 00:35:29,930
+minus x's reserves one hundred thousand three
+
+452
+00:35:29,930 --> 00:35:35,250
+hundred thousand dollars so how much is the
+
+453
+00:35:35,250 --> 00:35:40,870
+required reserve ratio أبو جزر؟So the required
+
+454
+00:35:40,870 --> 00:35:45,250
+reserve ratio equals required reserves over
+
+455
+00:35:45,250 --> 00:35:49,070
+deposits equals
+
+456
+00:35:49,070 --> 00:35:57,130
+300000 over 2 million dollars equals how much
+
+457
+00:35:57,130 --> 00:36:07,920
+exactly 15% right صعب الأمورلنذهب إلى هذا المثال
+
+458
+00:36:07,920 --> 00:36:14,620
+كما ترى كل شيء مُعطلوب هنا كما
+
+459
+00:36:14,620 --> 00:36:22,860
+ترى مقالات المالية 1.2 مليون ومقالات المالية 6.8
+
+460
+00:36:22,860 --> 00:36:31,300
+ومقالات المالية 8 مليون ومقالات المالية 8 مليون
+
+461
+00:36:31,300 --> 00:36:33,840
+ومقالات المالية 8 مليون ومقالات المالية 8 مليون
+
+462
+00:36:36,840 --> 00:36:41,340
+Okay, let's go to the exercise of the required
+
+463
+00:36:41,340 --> 00:36:44,840
+reserve ratio if the required reserve ratio equals
+
+464
+00:36:44,840 --> 00:36:50,920
+or is is 15% the first charter bank is what؟ يعني
+
+465
+00:36:50,920 --> 00:36:54,480
+لو suppose ان required reserves عندي ratio بيساوي
+
+466
+00:36:54,480 --> 00:36:58,080
+15% كداش عندي required reserves في هذا الحالة in
+
+467
+00:36:58,080 --> 00:37:02,940
+this case عشان نشوف شو هوضع ال bank So as you see
+
+468
+00:37:02,940 --> 00:37:12,390
+ان required reserve ratioequals 15% required
+
+469
+00:37:12,390 --> 00:37:18,670
+reserve ratio equals 15% right ومعطيني reserves
+
+470
+00:37:18,670 --> 00:37:22,930
+بيسوي 1.2 طب قديش ال required reserve هذا السؤال
+
+471
+00:37:22,930 --> 00:37:26,090
+عشان أشوف شو وضع البنك how much is the required
+
+472
+00:37:26,090 --> 00:37:32,590
+reserve required reserve ratio times deposits صح
+
+473
+00:37:34,130 --> 00:37:42,430
+equals 15% times deposits 8 million equals how
+
+474
+00:37:42,430 --> 00:37:51,030
+much? 1.2 مليون دولار معناه الكلام ايش ان ال
+
+475
+00:37:51,030 --> 00:37:54,090
+required reserve ratio او sorry required reserve
+
+476
+00:37:54,090 --> 00:37:57,870
+بتسوي ايش؟ reserves وبالتالي X is reserve ايش ماله
+
+477
+00:37:57,870 --> 00:38:02,940
+يسوي؟إذا كانت المقاومة X صفر بساوي صفر بساوي صفر
+
+478
+00:38:02,940 --> 00:38:03,280
+بساوي صفر بساوي صفر بساوي صفر بساوي صفر بساوي صفر
+
+479
+00:38:03,280 --> 00:38:06,460
+بساوي صفر بساوي صفر بساوي صفر بساوي صفر بساوي صفر
+
+480
+00:38:06,460 --> 00:38:09,420
+بساوي صفر بساوي صفر بساوي صفر بساوي صفر بساوي صفر
+
+481
+00:38:09,420 --> 00:38:09,420
+بساوي صفر بساوي صفر بساوي صفر بساوي صفر بساوي صفر
+
+482
+00:38:09,420 --> 00:38:11,480
+بساوي صفر بساوي صفر بساوي صفر بساوي صفر بساوي صفر
+
+483
+00:38:11,480 --> 00:38:20,080
+بساوي صفر بساوي صفر بساوي
+
+484
+00:38:20,080 --> 00:38:24,680
+صفر
+
+485
+00:38:24,680 --> 00:38:25,140
+ب
+
+486
+00:38:29,810 --> 00:38:34,330
+equals 1.2 هذا يعني أن مقاومة المقاومات كلها
+
+487
+00:38:34,330 --> 00:38:41,890
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة
+
+488
+00:38:41,890 --> 00:38:46,910
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة
+
+489
+00:38:46,910 --> 00:38:48,190
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة
+
+490
+00:38:48,190 --> 00:38:51,750
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة
+
+491
+00:38:51,750 --> 00:38:55,570
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة مقاومة
+
+492
+00:38:55,570 --> 00:39:12,020
+مقاومة مقاومة مقاومة مقاومة مقاومة مقاعندما تقرر
+
+493
+00:39:12,020 --> 00:39:22,060
+الـ X بالمقارنة
+
+494
+00:39:22,060 --> 00:39:23,340
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+495
+00:39:23,340 --> 00:39:25,960
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+496
+00:39:25,960 --> 00:39:27,040
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+497
+00:39:27,040 --> 00:39:27,660
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+498
+00:39:27,660 --> 00:39:27,660
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+499
+00:39:27,660 --> 00:39:33,030
+بالمقارنةأصبح 5% وشركة الشرطة الأولى استمرت في حفظ
+
+500
+00:39:33,030 --> 00:39:39,590
+1.2 مليون دولار 1 مليون 200 ألف دولار في مقاوماتها
+
+501
+00:39:39,590 --> 00:39:41,110
+مقاوماتها مقاوماتها مقاوماتها مقاوماتها مقاوماتها
+
+502
+00:39:41,110 --> 00:39:41,450
+مقاوماتها مقاوماتها مقاوماتها مقاوماتها مقاوماتها
+
+503
+00:39:41,450 --> 00:39:41,890
+مقاوماتها مقاوماتها مقاوماتها مقاوماتها مقاوماتها
+
+504
+00:39:41,890 --> 00:39:42,490
+مقاوماتها مقاوماتها مقاوماتها مقاوماتها مقاوماتها
+
+505
+00:39:42,490 --> 00:39:51,870
+مقاوماتها مقاوماتها مقاوماتها مقاوماتها مقاوماتها
+
+506
+00:39:53,580 --> 00:39:57,480
+هول قدش اندي free reserves 1.2 مليون يعني free
+
+507
+00:39:57,480 --> 00:40:03,580
+reserves اندي one point two one million point two
+
+508
+00:40:03,580 --> 00:40:09,080
+hundred thousand dollars the question is ال X's
+
+509
+00:40:09,080 --> 00:40:12,440
+reserve equals how much this is the question so we
+
+510
+00:40:12,440 --> 00:40:15,920
+have to calculate the required reserve صح؟ and
+
+511
+00:40:15,920 --> 00:40:20,080
+then the X's reserve صح؟ so the required reserve
+
+512
+00:40:20,080 --> 00:40:22,560
+equals five percent
+
+513
+00:40:31,970 --> 00:40:38,830
+400000 400000 400000
+
+514
+00:40:38,830 --> 00:40:45,550
+400000 400000 400000 400000 400000 400000 400000
+
+515
+00:40:45,550 --> 00:40:50,870
+400000 400000 400000 400000 400000 400000 400000
+
+516
+00:40:50,870 --> 00:40:50,870
+400000 400000 400000 400000 400000 400000 400000
+
+517
+00:40:50,870 --> 00:40:50,870
+400000 400000 400000 400000 400000 400000 400000
+
+518
+00:40:50,870 --> 00:40:50,870
+400000 400000 400000 400000 400000 400000 400000
+
+519
+00:40:50,870 --> 00:40:50,870
+400000 400000 400000 400000 400000 400000 400000
+
+520
+00:40:50,870 --> 00:40:50,870
+400000 400000 400000 400000 400000 400000 400000
+
+521
+00:40:50,870 --> 00:40:50,990
+400000 400000 400000 400000 400000 400000 400000
+
+522
+00:40:50,990 --> 00:40:50,990
+400000 400000 400000 400000 400000 400000 400000
+
+523
+00:40:50,990 --> 00:40:50,990
+400000 400000 400000 400000 400000 400000 400000
+
+524
+00:40:50,990 --> 00:40:50,990
+400000 400000 400000 400000 400000 400000 400000
+
+525
+00:40:50,990 --> 00:40:50,990
+400000 400000 400000 400000 400000 400000 400000
+
+526
+00:40:50,990 --> 00:40:50,990
+400000 400000 400000 400000 400000 400000 400000
+
+527
+00:40:50,990 --> 00:40:50,990
+400000 400000 400000 400000 400000 400000 400000
+
+528
+00:40:50,990 --> 00:40:50,990
+400000 400000 400000 400000 400000 400000 400000
+
+529
+00:40:50,990 --> 00:40:54,770
+400000 400000 400000 400000equals the total
+
+530
+00:40:54,770 --> 00:40:58,550
+reserves or reserves minus the required reserves
+
+531
+00:40:58,550 --> 00:41:02,170
+so the total reserves equals how much كداش one
+
+532
+00:41:02,170 --> 00:41:07,110
+million two hundred thousand minus the required
+
+533
+00:41:07,110 --> 00:41:11,790
+reserve so
+
+534
+00:41:11,790 --> 00:41:19,210
+the excess reserve eight hundred thousand dollars
+
+535
+00:41:19,210 --> 00:41:22,550
+right صعب؟
+
+536
+00:41:24,790 --> 00:41:34,230
+لنذهب إلى هذا المثال .. كما ترى .. المقاومات
+
+537
+00:41:34,230 --> 00:41:36,130
+الجديدة .. مقاومات الريكويلد .. ومقاومات الريكويلد
+
+538
+00:41:36,130 --> 00:41:40,550
+.. ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+539
+00:41:40,550 --> 00:41:40,590
+ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+540
+00:41:40,590 --> 00:41:40,770
+ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+541
+00:41:40,770 --> 00:41:41,850
+ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+542
+00:41:41,850 --> 00:41:44,170
+ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+543
+00:41:44,170 --> 00:41:48,170
+ومقاومات الريكويلد .. ومقاومات الريكويلد ..
+
+544
+00:41:48,170 --> 00:41:53,830
+ومقاومات الريكويلد .. ومقاومإذاً كداش الـ required
+
+545
+00:41:53,830 --> 00:41:58,690
+reserve ratio؟ خمسة في المية، تمام؟ راحوا .. راحوا
+
+546
+00:41:58,690 --> 00:42:02,370
+البنك ماتي loans بقدرش؟ بخمسة وتسعين ألف، تمام؟
+
+547
+00:42:02,370 --> 00:42:06,850
+صح؟ صح راحوا اللي .. اللي أخد ال loan هذا حطه في
+
+548
+00:42:06,850 --> 00:42:12,250
+بنك تاني، in the second bank خمسة وتسعين في المية
+
+549
+00:42:12,250 --> 00:42:17,260
+as a deposit in the second bankالشخص التاني عمل
+
+550
+00:42:17,260 --> 00:42:20,840
+deduction بخمسة في المية بال reserves هذا وصار
+
+551
+00:42:20,840 --> 00:42:24,060
+عنده قداش required reserve هلقدر وصار ميعطى loans
+
+552
+00:42:24,060 --> 00:42:30,440
+هلقدر الشخص التاني الشخص التاني شو عمل؟ أخد هذا
+
+553
+00:42:30,440 --> 00:42:35,080
+المبلغ as a loan وراح حاطهم في بنك تالت هيوم as a
+
+554
+00:42:35,080 --> 00:42:40,770
+depositThe third bank ايش عمل؟ عمل deduction بخمسة
+
+555
+00:42:40,770 --> 00:42:43,650
+في المية قداش خمسة في المية من هذا المبلغ هيوم
+
+556
+00:42:43,650 --> 00:42:47,890
+هلقد وبالتالي بيعمل loan هلقد and so on طيب السؤال
+
+557
+00:42:47,890 --> 00:42:50,630
+بيقولنا let's go to the .. refer to the scenario
+
+558
+00:42:50,630 --> 00:42:54,510
+what is the required reserve ratio لو required
+
+559
+00:42:54,510 --> 00:42:58,990
+reserves over deposits صح؟ طيب what is the money
+
+560
+00:42:58,990 --> 00:43:01,410
+multiplier in this economy let's come back to the
+
+561
+00:43:01,410 --> 00:43:05,590
+money multiplier هلأ الصورة واضحة بالنسبالكم صارت
+
+562
+00:43:05,590 --> 00:43:10,580
+شباب؟بموضوع ال required reserve ratio و ال excess
+
+563
+00:43:10,580 --> 00:43:11,080
+reserves
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/5La1lkc1hBw_postprocess.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/5La1lkc1hBw_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..0a461cd7a380d0a92cadd10469b4d35c3d3ab100
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/5La1lkc1hBw_postprocess.srt
@@ -0,0 +1,2408 @@
+1
+00:00:20,670 --> 00:00:21,390
+السلام عليكم ورحمة الله ورحمة الله ورحمة الله
+
+2
+00:00:21,390 --> 00:00:23,970
+ورحمة الله ورحمة الله ورحمة الله ورحمة الله ورحمة
+
+3
+00:00:23,970 --> 00:00:24,850
+الله ورحمة الله ورحمة الله ورحمة الله ورحمة الله
+
+4
+00:00:24,850 --> 00:00:27,250
+ورحمة الله ورحمة الله ورحمة الله ورحمة الله ورحمة
+
+5
+00:00:27,250 --> 00:00:30,770
+الله ورحمة الله ورحمة الله ورحمة الله ورحمة الله
+
+6
+00:00:30,770 --> 00:00:42,970
+ورحمة الله ورحمة
+
+7
+00:00:42,970 --> 00:00:46,790
+الله ورحمة
+
+8
+00:00:46,790 --> 00:00:52,970
+اللهوالـ GDP المميز في الوقت طويل وفي الوقت قصير
+
+9
+00:00:52,970 --> 00:00:57,710
+كما تشاهد في هذا البرنامج، لدينا الـ Equilibrium
+
+10
+00:00:57,710 --> 00:01:01,710
+هذا هو المساعدة الأساسية الأساسية الأساسية
+
+11
+00:01:01,710 --> 00:01:04,170
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+12
+00:01:04,170 --> 00:01:05,170
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+13
+00:01:05,170 --> 00:01:06,070
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+14
+00:01:06,070 --> 00:01:12,230
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+15
+00:01:12,230 --> 00:01:17,350
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+16
+00:01:17,350 --> 00:01:18,180
+الأساسية الأساسية الأساسية الأساسية الأساسيةكما
+
+17
+00:01:18,180 --> 00:01:24,900
+ذكرنا أن إذا كانت الحكومة تستخدم حكومة اتفاقية او
+
+18
+00:01:24,900 --> 00:01:27,800
+حكومة مالية اتفاقية أو مالية اتفاقية أو مالية
+
+19
+00:01:27,800 --> 00:01:27,820
+اتفاقية أو مالية اتفاقية أو مالية اتفاقية أو مالية
+
+20
+00:01:27,820 --> 00:01:29,940
+اتفاقية أو مالية اتفاقية أو مالية اتفاقية او مالية
+
+21
+00:01:29,940 --> 00:01:34,560
+اتفاقية او مالية اتفاقية او مالية اتفاقية او مالية
+
+22
+00:01:34,560 --> 00:01:39,100
+اتفاقية اتفاقية او مالية اتفاقية اتفاقية اتفاقية
+
+23
+00:01:39,100 --> 00:01:42,940
+اتفاقية ات
+
+24
+00:01:44,940 --> 00:01:48,900
+تحول إلى كلمة صحيحة وطرق مطالبة المطالبة من مطالبة
+
+25
+00:01:48,900 --> 00:01:54,200
+المطالبة 1 إلى مطالبة المطالبة 2 وهو يعني أننا
+
+26
+00:01:54,200 --> 00:02:00,560
+لدينا نقطة ايقاليبريان جديدة هنا اي وان اي اتو
+
+27
+00:02:00,560 --> 00:02:07,760
+الأسعار كانت تزيد من نقطة P1 إلى P2 في هذه الحالة
+
+28
+00:02:07,760 --> 00:02:13,180
+يزيد Y من Y1 إلى Y2
+
+29
+00:02:18,120 --> 00:02:23,700
+عندما يزال السعر يزال يزال يزال يزال يزال يزال
+
+30
+00:02:23,700 --> 00:02:28,430
+يزالالتحويل إلى تحويل الحكومة، فهنا نتحدث عن تحويل
+
+31
+00:02:28,430 --> 00:02:33,050
+الحكومة، رغم أنه يكون مالي أو فسكت، فهذا يؤدي إلى
+
+32
+00:02:33,050 --> 00:02:36,570
+تحويل
+
+33
+00:02:36,570 --> 00:02:42,170
+المساعدة المالية، يؤدي إلى تحويل R، تحويل I،
+
+34
+00:02:42,170 --> 00:02:44,530
+تحويل، تحويل المساعدة التجارية أو التحويل التجارية
+
+35
+00:02:46,720 --> 00:02:49,080
+لذلك Y ستزال يزال يزال يزال يزال يزال يزال يزال
+
+36
+00:02:49,080 --> 00:02:53,840
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+37
+00:02:53,840 --> 00:02:56,160
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+38
+00:02:56,160 --> 00:03:01,780
+يزال يزال يزال
+
+39
+00:03:01,780 --> 00:03:01,920
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+40
+00:03:01,920 --> 00:03:02,240
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+41
+00:03:02,240 --> 00:03:02,280
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+42
+00:03:02,280 --> 00:03:03,440
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+43
+00:03:03,440 --> 00:03:05,560
+يزال يزال
+
+44
+00:03:16,340 --> 00:03:23,360
+وهذا يعني اتقال في المصادر المجاورة، فهناك تحويل
+
+45
+00:03:23,360 --> 00:03:27,880
+مجاور للأعلى ومجاورة المصادر المجاورة، فهناك تحويل
+
+46
+00:03:27,880 --> 00:03:33,340
+مجاور للأعلى من المصادر المجاورة 1 إلى المصادر
+
+47
+00:03:33,340 --> 00:03:38,700
+المجاورة 2بالتالي، في هذه الحالة، ستزداد الأسعار
+
+48
+00:03:38,700 --> 00:03:46,300
+من P2 إلى P3، وY ستتخلص من Y2 إلى Y1، وهو الـ GDP
+
+49
+00:03:46,300 --> 00:03:47,360
+الممكنة
+
+50
+00:03:55,190 --> 00:04:00,350
+لذلك كما ترى هناك تغيير للمساعدة التجارية من
+
+51
+00:04:00,350 --> 00:04:04,010
+المساعدة التجارية 1 إلى 2 مما يعني أنه يزيد
+
+52
+00:04:04,010 --> 00:04:10,340
+السعوديين، لكن ماهو أفضل لنا؟ لماذا 1؟without
+
+53
+00:04:10,340 --> 00:04:14,840
+increasing the prices or y1 here is the potential
+
+54
+00:04:14,840 --> 00:04:19,460
+GDP يعني أقصى حاجة ممكن نوصلها هو y1 صحيح أن ال y1
+
+55
+00:04:19,460 --> 00:04:22,400
+increase بعدين then decrease which is better for
+
+56
+00:04:22,400 --> 00:04:28,280
+us for the economy y1 without increasing the
+
+57
+00:04:28,280 --> 00:04:32,800
+prices or without inflation or y1 with inflation
+
+58
+00:04:32,800 --> 00:04:39,200
+without inflation exactlyY1 هنا في الواقع الأول في
+
+59
+00:04:39,200 --> 00:04:47,320
+الـ A1 يسمى الـ GDP الممكنة بدون الإنفلاش Y1 هنا
+
+60
+00:04:47,320 --> 00:04:52,040
+إذا ارتفع التطبيق التجاري و بعد ذلك تتخلص التطبيق
+
+61
+00:04:52,040 --> 00:04:58,360
+التجاري هذا يعني أننا سنصل أو سنعود إلى القدرة أو
+
+62
+00:04:58,360 --> 00:05:02,880
+استخدام القدرة التجارية أو GDP الممكنة ولكن لدينا
+
+63
+00:05:02,880 --> 00:05:08,180
+ارتفاع الأسعاروهذا يعني أننا لدينا GDP ممكنة مع
+
+64
+00:05:08,180 --> 00:05:11,980
+زيادة الأسعار بدون تغيير في الوصول الانتجاري،
+
+65
+00:05:11,980 --> 00:05:18,660
+ويعني GDP ممكنة مع تغيير الانتجار، لذلك نحن سنفضر
+
+66
+00:05:18,660 --> 00:05:28,000
+أن نعمل في Y1 بدون تغيير الانتجار، صح؟و اذا وصلنا
+
+67
+00:05:28,000 --> 00:05:32,860
+احنا اصلا ل A1 هنا خلاص مش لازم ان انا اروح اعمل
+
+68
+00:05:32,860 --> 00:05:36,840
+increasing of money supply او using an
+
+69
+00:05:36,840 --> 00:05:42,380
+expansionary fiscal or monetary policyالتحويل من
+
+70
+00:05:42,380 --> 00:05:49,580
+تحويل الأسعار إلى تحويل الأسعار ثم تحويل الأسعار
+
+71
+00:05:49,580 --> 00:05:51,560
+إلى تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+72
+00:05:51,560 --> 00:05:51,700
+الأسعار ثم تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+73
+00:05:51,700 --> 00:05:51,760
+الأسعار ثم تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+74
+00:05:51,760 --> 00:05:51,940
+الأسعار ثم تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+75
+00:05:51,940 --> 00:05:52,100
+الأسعار ثم تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+76
+00:05:52,100 --> 00:05:56,420
+الأسعار ثم تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+77
+00:05:56,420 --> 00:06:06,640
+الأسعار ثم تحويل الأسعار ثم
+
+78
+00:06:06,830 --> 00:06:12,550
+وما هو أفضل بالنسبة لي A1 او A3؟ A1 أفضل من A3 لأن
+
+79
+00:06:12,550 --> 00:06:18,390
+A1 يعني أنني سأصبح في Y1، صحيح؟ الوصول المجلدية
+
+80
+00:06:18,390 --> 00:06:27,810
+سيكون Y1 بقيمة P1 ولكن A3 يعني نفس الوصول المجلدية
+
+81
+00:06:27,810 --> 00:06:35,410
+بقيمة أعلى، مظبوط؟ لنذهب إلى مشكلة أخرى
+
+82
+00:06:49,710 --> 00:06:56,150
+كما ذكرنا سابقًا، نستطيع
+
+83
+00:06:56,150 --> 00:06:57,990
+ان نقوم باستخدام مجموعة تدفع مجموعة تدفع مجموعة
+
+84
+00:06:57,990 --> 00:06:58,830
+تدفع مجموعة تدفع مجموعة تدفع مجموعة تدفع مجموعة
+
+85
+00:06:58,830 --> 00:06:59,230
+تدفع مجموعة تدفع مجموعة تدفع مجموعة تدفع مجموعة
+
+86
+00:06:59,230 --> 00:07:00,190
+تدفع مجموعة تدفع مجموعة تدفع مجموعة تدفع مجموعة
+
+87
+00:07:00,190 --> 00:07:00,830
+تدفع مجموعة تدفع مجموعة تدفع مجموعة تدفع مجموعة
+
+88
+00:07:00,830 --> 00:07:18,470
+تدفع مجموعة تدفع مجموعة تدفع مجموعة تدفع م
+
+89
+00:07:18,580 --> 00:07:22,900
+في الفترة الصغيرة أو الفترة الصغيرة للغاية إذا كنا
+
+90
+00:07:22,900 --> 00:07:27,720
+نستخدم قرار اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+91
+00:07:27,720 --> 00:07:28,520
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+92
+00:07:28,520 --> 00:07:32,440
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+93
+00:07:32,440 --> 00:07:32,500
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+94
+00:07:32,500 --> 00:07:33,000
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+95
+00:07:47,740 --> 00:07:52,800
+إذا استخدمنا قياسية اتفاق أو قياسية اتفاق اتفاق
+
+96
+00:07:52,800 --> 00:07:55,620
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+97
+00:07:55,620 --> 00:07:59,460
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+98
+00:07:59,460 --> 00:08:03,640
+اتفاق اتفاق اتفاق اتفاق اتفاق
+
+99
+00:08:03,640 --> 00:08:05,420
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+100
+00:08:05,420 --> 00:08:06,320
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+101
+00:08:06,320 --> 00:08:17,530
+اتفاق اتفاincreasing from Y to Y0 to Y1 مصبوط؟ مين
+
+102
+00:08:17,530 --> 00:08:21,210
+اللي تتغير فيه أعلى؟ الـY أو الـPrices؟ الـY،
+
+103
+00:08:21,210 --> 00:08:23,490
+الـY، الـY، الـY، الـY، الـY، الـY، الـY، الـY،
+
+104
+00:08:23,490 --> 00:08:24,190
+الـY، الـY، الـY، الـY، الـY، الـY، الـY، الـY،
+
+105
+00:08:24,190 --> 00:08:25,550
+الـY، الـY، الـY، الـY، الـY، الـY، الـY، الـY،
+
+106
+00:08:25,550 --> 00:08:25,570
+الـY، الـY، الـY، الـY، الـY، الـY، الـY، الـY،
+
+107
+00:08:25,570 --> 00:08:30,750
+الـY، الـY، الـY، الـY، الـY،
+
+108
+00:08:40,590 --> 00:08:46,270
+جليل exactly it's a small بظبط ولا لأ صح لأنه
+
+109
+00:08:46,270 --> 00:08:48,990
+effective وبتقل ال increasing the aggregate output
+
+110
+00:08:48,990 --> 00:08:54,290
+is larger than طب why is the change or does the
+
+111
+00:08:54,290 --> 00:08:57,130
+change in aggregate output is larger than the
+
+112
+00:08:57,130 --> 00:08:59,270
+change in the prices here okay
+
+113
+00:09:14,620 --> 00:09:20,180
+exactly but why my question is why in the short
+
+114
+00:09:20,180 --> 00:09:26,240
+run here why does the change in y is larger than
+
+115
+00:09:26,240 --> 00:09:31,010
+the change in the price levelExactly thank you
+
+116
+00:09:31,010 --> 00:09:35,130
+because the slope of aggregate supply curve in the
+
+117
+00:09:35,130 --> 00:09:39,990
+short run and the very short run is small or it
+
+118
+00:09:39,990 --> 00:09:43,930
+should be more elastic than the long run period or
+
+119
+00:09:43,930 --> 00:09:48,530
+stage صح exactly the elasticity that you have
+
+120
+00:09:48,530 --> 00:09:53,150
+studied in the micro economics تمام طيب let's go
+
+121
+00:09:59,560 --> 00:10:02,460
+على مجموعة الـ Aggregate curve أو مجموعة الـ
+
+122
+00:10:02,460 --> 00:10:09,060
+Aggregate supply curve، لا تعمل بشكل جيد على
+
+123
+00:10:09,060 --> 00:10:13,040
+المجموعة الـ Aggregate supply curve أو
+
+124
+00:10:13,040 --> 00:10:14,100
+مجموعة الـ Aggregate supply curve أو مجموعة الـ
+
+125
+00:10:14,100 --> 00:10:14,180
+Aggregate supply curve أو مجموعة الـ Aggregate
+
+126
+00:10:14,180 --> 00:10:16,200
+supply curve أو مجموعة الـ Aggregate supply curve
+
+127
+00:10:16,200 --> 00:10:17,120
+أو مجموعة الـ Aggregate supply curve أو مجموعة الـ
+
+128
+00:10:17,120 --> 00:10:17,380
+Aggregate supply curve أو مجموعة الـ Aggregate
+
+129
+00:10:17,380 --> 00:10:17,460
+أو مجموعة الـ Aggregate supply curve أو مجموعة الـ
+
+130
+00:10:17,460 --> 00:10:18,740
+Aggregate supply curve أو مجموعة الـ Aggregate
+
+131
+00:10:18,740 --> 00:10:21,200
+supply curve أو مجموعة الـ Aggregate supply curve
+
+132
+00:10:21,200 --> 00:10:23,180
+أو مجموعة الـ Aggregate supply curve أو مجموعة
+
+133
+00:10:24,860 --> 00:10:30,560
+مثلًا، إذا كنا نستخدم قيادة إتصالية، فهذا يسبب
+
+134
+00:10:30,560 --> 00:10:36,720
+فيها ارتفاع صغير في الـY وارتفاع كبير في الأسعار
+
+135
+00:10:36,720 --> 00:10:42,040
+لأن مستقبل مجموعة الـSupply Curve قريب من مجموعة
+
+136
+00:10:42,040 --> 00:10:46,840
+اتصالية مرتفعة. لكن في هذه الحالة، ماذا تقول؟ ماذا
+
+137
+00:10:46,840 --> 00:10:52,210
+عن إتصال المجموعة في الـPlanned Investment؟لدينا
+
+138
+00:10:52,210 --> 00:10:57,330
+مجموعات كبيرة أو مجموعات كبيرة في الاستثمار
+
+139
+00:10:57,330 --> 00:11:02,130
+المخطط، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم،
+
+140
+00:11:02,130 --> 00:11:02,250
+نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم،
+
+141
+00:11:02,250 --> 00:11:02,490
+نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم،
+
+142
+00:11:02,490 --> 00:11:05,530
+نعم، نعم، نعم، نعم، نعم، نعم،
+
+143
+00:11:05,530 --> 00:11:05,650
+ن
+
+144
+00:11:09,110 --> 00:11:12,170
+سيكون حرارة المصادر المجاورة أقل أو أقل ، لذلك في
+
+145
+00:11:12,170 --> 00:11:15,710
+هذه الحالة إذا كنا نستخدم اتصال مصادر المصادر
+
+146
+00:11:15,710 --> 00:11:18,350
+المجاورة ، فهذا يؤدي إلى تحويل مصادر المصادر
+
+147
+00:11:18,350 --> 00:11:19,690
+المجاورة إلى حرارة المصادر المجاورة ، من حرارة
+
+148
+00:11:19,690 --> 00:11:21,510
+المصادر المجاورة لا إلى حرارة المصادر المجاورة إذا
+
+149
+00:11:21,510 --> 00:11:28,050
+كان لدينا نقطة إيقاف جديدة P لا P إلى P ، وهو يعني
+
+150
+00:11:29,390 --> 00:11:35,030
+أو نحن لدينا أكبر أزمة في الأسعار أو الانفلاك مع
+
+151
+00:11:35,030 --> 00:11:39,090
+ازمة صغيرة في الـ aggregate output لذلك في هذه
+
+152
+00:11:39,090 --> 00:11:47,730
+الحالة تقنية الانفلاك ماذا؟ مفيدة أو ليس مفيدة؟
+
+153
+00:11:47,730 --> 00:11:51,250
+لذلك لا سياسة المالية ولا النقدي فعالين في هذه
+
+154
+00:11:51,250 --> 00:11:57,610
+الحالة، مظبوط او لا؟ طيب، ماذا عن المرتبط؟ في هذه
+
+155
+00:11:57,610 --> 00:12:02,190
+الحالةفاكرين الـ Multiplier؟ اللي هو Delta Y
+
+156
+00:12:02,190 --> 00:12:05,870
+Multiplier الـ Government Spending Multiplier
+
+157
+00:12:05,870 --> 00:12:11,390
+Delta Y over Delta G الزيادة اللي صارت في ال
+
+158
+00:12:11,390 --> 00:12:16,830
+Government Spending زادت ال Y بالنسبة بسيطة جدا،
+
+159
+00:12:16,830 --> 00:12:19,750
+صح؟ مظبوط؟ يعني سببز أننا زدنا ال Government
+
+160
+00:12:19,750 --> 00:12:25,700
+Spending ال Y ممكن تزيد بحاجة بسيطة، smallبالنسبة
+
+161
+00:12:25,700 --> 00:12:29,780
+لهذا البرنامج قريب من أزرار أزرار في هذه الحالة
+
+162
+00:12:29,780 --> 00:12:33,120
+إذا كانت رحلة عضوية بالتأكيد البرنامج سيكون
+
+163
+00:12:33,120 --> 00:12:37,880
+أزرارًا أزرارًا صح؟ كله هذا الكلام أنه في مجموعة
+
+164
+00:12:37,880 --> 00:12:43,500
+عضوية الأسعار البرنامج لا يعمل جيدًا والبرنامج
+
+165
+00:12:43,500 --> 00:12:48,450
+قريبة من أزرار أزرارإذا كانت المستوى التجاري تكون
+
+166
+00:12:48,450 --> 00:12:52,850
+خطوة مرتفعة، في هذه الحالة، فإن أزمة الحكومة تتسبب
+
+167
+00:12:52,850 --> 00:12:53,910
+في أزمة التطبيقات التجارية تتسبب في أزمة التطبيقات
+
+168
+00:12:53,910 --> 00:12:55,350
+التجارية تتسبب في أزمة التطبيقات التجارية تتسبب في
+
+169
+00:12:55,350 --> 00:12:58,770
+أزمة التطبيقات التجارية تتسبب في أزمة التطبيقات
+
+170
+00:12:58,770 --> 00:13:01,230
+التجارية تتسبب في أزمة التطبيقات التجارية تتسبب في
+
+171
+00:13:01,230 --> 00:13:01,590
+أزمة التطبيقات التجارية تتسبب في أزمة التطبيقات
+
+172
+00:13:01,590 --> 00:13:02,550
+التجارية تتسبب في أزمة التطبيقات التجارية تتسبب في
+
+173
+00:13:02,550 --> 00:13:09,710
+أزمة التطبيقات التجارية تتسبب في أزمة
+
+174
+00:13:09,710 --> 00:13:15,040
+التطبيقات التجإذا كان الحكومة تستخدم حكومة عملية
+
+175
+00:13:15,040 --> 00:13:21,600
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+176
+00:13:21,600 --> 00:13:22,420
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+177
+00:13:22,420 --> 00:13:23,240
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+178
+00:13:23,240 --> 00:13:23,280
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+179
+00:13:23,280 --> 00:13:23,300
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+180
+00:13:23,300 --> 00:13:27,260
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+181
+00:13:27,260 --> 00:13:28,100
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+182
+00:13:28,100 --> 00:13:31,300
+عملية عملية عملية عملية
+
+183
+00:13:35,500 --> 00:13:41,540
+وهذا يعني أننا لدينا إزالة في الأسعار بدون تغيير
+
+184
+00:13:41,540 --> 00:13:50,400
+في الـ aggregate output لذلك لا يوجد تغيير في الـ
+
+185
+00:13:50,400 --> 00:13:54,960
+aggregate output لذلك يكون الـ Y موجودة في Y1
+
+186
+00:13:58,420 --> 00:14:03,360
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+187
+00:14:03,360 --> 00:14:05,340
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+188
+00:14:05,340 --> 00:14:05,660
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+189
+00:14:05,660 --> 00:14:07,480
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+190
+00:14:07,480 --> 00:14:09,440
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+191
+00:14:09,440 --> 00:14:09,580
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+192
+00:14:09,580 --> 00:14:10,340
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+193
+00:14:10,340 --> 00:14:17,900
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+194
+00:14:17,900 --> 00:14:24,320
+المزيد منصح؟ so in this case we have only
+
+195
+00:14:24,320 --> 00:14:27,940
+exchanges and or increasing the price levels or
+
+196
+00:14:27,940 --> 00:14:32,680
+inflation تمام؟ وهذه المنطقة بيسموها inflationary
+
+197
+00:14:32,680 --> 00:14:40,500
+gap فجوة تدخمية تمام؟ اه هذا جاي نعليها لغاية ان
+
+198
+00:14:40,500 --> 00:14:45,260
+شاء الله so when the economy works
+
+199
+00:14:47,710 --> 00:14:54,210
+أو تدفع في القوة هنا موضوع القوة الـ P' نحن لدينا
+
+200
+00:14:54,210 --> 00:14:59,510
+القوة أو القوة الكامة فإن إزالة أو استخدام اتفاق
+
+201
+00:14:59,510 --> 00:15:04,530
+فاسكال أو اتفاق مواليتور يتسبب في إزالة الأسعار
+
+202
+00:15:04,530 --> 00:15:11,650
+فقط بدون تغيير ولماذا؟ عندما نعمل قريتاthe
+
+203
+00:15:11,650 --> 00:15:14,770
+capacity يعني جريبين من ال capacity in this case
+
+204
+00:15:14,770 --> 00:15:17,570
+the expansion of fiscal policy leads to increasing
+
+205
+00:15:17,570 --> 00:15:21,270
+the prices with a smaller change in Y or a smaller
+
+206
+00:15:21,270 --> 00:15:25,330
+change in the aggregate output مين مش فاهم قايدله
+
+207
+00:15:25,330 --> 00:15:30,170
+في هذا الجزيه؟ واضحة؟ طب أحكي عربة ولا مصر؟ تمام
+
+208
+00:15:30,170 --> 00:15:32,490
+أنا أحكي English أحسن؟ okay
+
+209
+00:15:50,500 --> 00:15:57,000
+طيب so as you see if the aggregate supply curve is
+
+210
+00:15:57,000 --> 00:16:02,620
+a vertical in the long term إذا كان نعمل diagram
+
+211
+00:16:02,620 --> 00:16:07,580
+هيك if
+
+212
+00:16:07,580 --> 00:16:10,860
+the aggregate supply curve is a vertical line in
+
+213
+00:16:10,860 --> 00:16:13,480
+this case neither
+
+214
+00:16:15,000 --> 00:16:18,880
+الخاصية المراقبة أو الخاصية المراقبة لديها أي
+
+215
+00:16:18,880 --> 00:16:23,460
+افتتاح على الاختصار المراقبة مظبوط هاي في الوقت
+
+216
+00:16:23,460 --> 00:16:27,860
+طويل الخاصية
+
+217
+00:16:27,860 --> 00:16:33,600
+المراقبة هي اتجارة رقمية هنا المزيد أو استخدام
+
+218
+00:16:33,600 --> 00:16:37,120
+خاصية المراقبة أو الخاصية المراقبة المراقبة
+
+219
+00:16:37,120 --> 00:16:37,700
+المراقبة المراقبة المراقبة المراقبة المراقبة
+
+220
+00:16:37,700 --> 00:16:38,600
+المراقبة المراقبة المراقبة المراقبة المراقبة
+
+221
+00:16:38,600 --> 00:16:40,280
+المراقبة المراقبة المراقبة المراقبة المراقبة
+
+222
+00:16:40,280 --> 00:16:42,320
+المراقبة
+
+223
+00:16:44,090 --> 00:16:48,210
+وهذا يعني أننا لدينا زيادة في الأسعار بدون تغيير
+
+224
+00:16:48,210 --> 00:16:51,030
+في الواقع ولماذا؟ لذلك، لا يوجد أي تغيير في
+
+225
+00:16:51,030 --> 00:16:56,850
+الاستخدام أو تغيير في الاستخدام أو تغيير في
+
+226
+00:16:56,850 --> 00:16:58,070
+الاستخدام أو تغيير في الاستخدام أو تغير في
+
+227
+00:16:58,070 --> 00:16:59,450
+الاستخدام أو تغير في الاستخدام أو تغير في
+
+228
+00:16:59,450 --> 00:17:00,870
+الاستخدام أو تغير في الاستخدام أو تغير في
+
+229
+00:17:00,870 --> 00:17:02,830
+الاستخدام أو تغير في الاستخدام أو تغير في
+
+230
+00:17:02,830 --> 00:17:03,790
+الاستخدام أو تغير في الاستخدام أو تغير في
+
+231
+00:17:03,790 --> 00:17:11,950
+الاستخدام أو تغير في الاستخدام أو
+
+232
+00:17:11,950 --> 00:17:21,440
+تغيروالـ crowding out أيضًا مظبوط لأن كل زيادات
+
+233
+00:17:21,440 --> 00:17:30,780
+اللي صارت في النتجة هيعمل backward مرة تانية دعونا
+
+234
+00:17:30,780 --> 00:17:37,800
+نذهب إلى هذا البرنامج باعتبار كينسيا البرنامج
+
+235
+00:17:37,800 --> 00:17:41,620
+باعتبار كينسيا البرنامج باعتبار كينسيا البرنامج
+
+236
+00:17:41,620 --> 00:17:45,150
+باعتبار كينسياflat or horizontal line and then
+
+237
+00:17:45,150 --> 00:17:48,950
+vertical line انا بتحكي عن very short run and long
+
+238
+00:17:48,950 --> 00:17:53,690
+run تمام خليني اعمل الرسم هنا وبعدين نعمل ال
+
+239
+00:17:53,690 --> 00:17:57,810
+analysis okay so
+
+240
+00:17:57,810 --> 00:18:02,650
+according to the keynesian view let's analyze the
+
+241
+00:18:02,650 --> 00:18:06,950
+policy effects or the policies effects or the
+
+242
+00:18:06,950 --> 00:18:09,810
+aggregate output according to the keynesian view
+
+243
+00:18:11,390 --> 00:18:19,390
+لدينا اتصالات او اتصالات او اتصالات او
+
+244
+00:18:19,390 --> 00:18:19,510
+اتصالات او اتصالات او اتصالات او اتصالات اتصالات
+
+245
+00:18:19,510 --> 00:18:23,870
+اتصالات اتصالات
+
+246
+00:18:23,870 --> 00:18:25,750
+اتصالات اتصالات اتصالات اتصالات اتصالات اتصالات
+
+247
+00:18:25,750 --> 00:18:26,910
+اتصالات اتصالات اتصالات اتصالات اتصالات اتصالات
+
+248
+00:18:26,910 --> 00:18:26,990
+اتصالات اتصالات اتصالات اتصالات اتصالات اتصالات
+
+249
+00:18:26,990 --> 00:18:28,090
+اتصالات اتصالات اتصالات اتصالات اتصالات اتصالات
+
+250
+00:18:28,090 --> 00:18:31,790
+اتصالات اتصالات اتصالات اتصالات اتصالات اتصالات
+
+251
+00:18:31,790 --> 00:18:36,070
+اتصالات اتصال
+
+252
+00:18:37,070 --> 00:18:46,130
+اعتبار الـ E1 او الـ E هنا سنقوم بالتحليق هذا هو
+
+253
+00:18:46,130 --> 00:18:55,150
+السبب في مجموعة الاسعار 1 C plus I plus G plus X
+
+254
+00:18:55,150 --> 00:19:03,030
+minus M اعتبار هذا الـ E1
+
+255
+00:19:04,380 --> 00:19:12,020
+وهذا هو اتجارة اتجارة Y اتجارة
+
+256
+00:19:12,020 --> 00:19:24,380
+Y اتجارة Y اتجارة Y اتجارة Y اتجارة Y اتجارة Y
+
+257
+00:19:24,380 --> 00:19:33,170
+اتجارة Y اتجارة Yالإيقاليبريام هنا يحدث عندما
+
+258
+00:19:33,170 --> 00:19:36,170
+تتجاوز المصادر المجاورة إلى طلب المجاور المجاور
+
+259
+00:19:36,170 --> 00:19:37,610
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+260
+00:19:37,610 --> 00:19:39,390
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+261
+00:19:39,390 --> 00:19:39,450
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+262
+00:19:39,450 --> 00:19:41,710
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+263
+00:19:41,710 --> 00:19:42,850
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+264
+00:19:42,850 --> 00:19:46,470
+المجاور المجاور
+
+265
+00:19:46,470 --> 00:19:48,370
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+266
+00:19:48,370 --> 00:19:53,250
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+267
+00:19:53,250 --> 00:19:59,370
+المجاور
+
+268
+00:19:59,370 --> 00:20:07,210
+المجاصح؟ So here we have what؟ Upward shifting of
+
+269
+00:20:07,210 --> 00:20:10,390
+the aggregate expenditure function and increasing
+
+270
+00:20:10,390 --> 00:20:12,970
+the aggregate demand. So suppose this is aggregate
+
+271
+00:20:12,970 --> 00:20:17,530
+demand 2. Here we have E2. What do you see? This
+
+272
+00:20:17,530 --> 00:20:25,810
+is P1 and P2 Y1 This
+
+273
+00:20:25,810 --> 00:20:27,730
+is Y1
+
+274
+00:20:29,470 --> 00:20:41,190
+Y2 صح او YF سببز ان YF هى Y Okay Y2 So the using
+
+275
+00:20:41,190 --> 00:20:44,010
+of an expansion fiscal policy leads to increasing
+
+276
+00:20:44,010 --> 00:20:47,290
+aggregate demand from a or a rightward shifting of
+
+277
+00:20:47,290 --> 00:20:49,350
+the aggregate demand from aggregate demand one to
+
+278
+00:20:49,350 --> 00:20:51,330
+aggregate demand two at the same time the
+
+279
+00:20:51,330 --> 00:20:54,510
+aggregate expenditure function increased and shift
+
+280
+00:20:54,510 --> 00:20:57,990
+to the upward there is upward shifting and the
+
+281
+00:20:57,990 --> 00:21:04,530
+aggregateexpenditure 2 this is aggregate
+
+282
+00:21:04,530 --> 00:21:10,930
+expenditure 2 sorry Y شو لسه aggregate expenditure
+
+283
+00:21:10,930 --> 00:21:17,370
+وين راح upward shifting بقى جاي بشكل parallel to
+
+284
+00:21:17,370 --> 00:21:20,250
+the previous case this is aggregate expenditure 2
+
+285
+00:21:20,250 --> 00:21:26,030
+this is E2 right تمام هذا شو يعمل في ال Y this is
+
+286
+00:21:26,030 --> 00:21:27,650
+Y1
+
+287
+00:21:30,900 --> 00:21:38,340
+Y2 مظبوط هنا شو لسه ال prices ماتغيرتش remains
+
+288
+00:21:38,340 --> 00:21:46,240
+constant P1 P2 P1 equals P2 صح طيب now the
+
+289
+00:21:46,240 --> 00:21:52,770
+capacity reached at point E2 here مظبوطهذا ال
+
+290
+00:21:52,770 --> 00:21:56,490
+capacity our full capacity utilization سببه ان ال
+
+291
+00:21:56,490 --> 00:21:59,730
+government راحت شو عامله increasing its spending
+
+292
+00:21:59,730 --> 00:22:03,910
+once again راحوا عاملين زيادة في ال aggregate
+
+293
+00:22:03,910 --> 00:22:10,150
+demand او ال government spending once againleads
+
+294
+00:22:10,150 --> 00:22:12,550
+to increasing aggregate expenditure and increase
+
+295
+00:22:12,550 --> 00:22:16,050
+aggregate demand but what shall .. what do you see
+
+296
+00:22:16,050 --> 00:22:18,590
+for the aggregate output؟ هلأ شو اللي بيصير؟ ال
+
+297
+00:22:18,590 --> 00:22:21,850
+aggregate demand will shift to the right once
+
+298
+00:22:21,850 --> 00:22:30,010
+again A D 3 تمام؟ شو اللي صار؟ this is A3 the
+
+299
+00:22:30,010 --> 00:22:34,310
+price is increased from B2 to B3 without a change
+
+300
+00:22:34,310 --> 00:22:37,790
+in Y in the long term this is Y3 طب نيجي للرسم
+
+301
+00:22:37,790 --> 00:22:41,380
+التاني يشوف شو اللي صار فيها؟الـ Increasing اللي
+
+302
+00:22:41,380 --> 00:22:43,420
+صار في ال aggregate demand او aggregate
+
+303
+00:22:43,420 --> 00:22:46,480
+expenditure هو عمل upward shifting للـ function
+
+304
+00:22:46,480 --> 00:22:56,840
+صح؟ إذا صار في عندى نعمله باللون الأزرق هيك this
+
+305
+00:22:56,840 --> 00:23:01,760
+is aggregate expenditure 3 وين جينا؟ Y increased
+
+306
+00:23:01,760 --> 00:23:13,050
+to Y3 مظبوط؟ صح؟طيب هاد المنطقة this is E3صار في
+
+307
+00:23:13,050 --> 00:23:16,050
+عندى increasing او upward shifting في الـ
+
+308
+00:23:16,050 --> 00:23:18,930
+aggregate expenditure من aggregate expenditure 2 ل
+
+309
+00:23:18,930 --> 00:23:23,770
+aggregate expenditure 3 صح؟ بس قولنا انه في عندى
+
+310
+00:23:23,770 --> 00:23:27,130
+fully crowding out بعد الـ full capacity
+
+311
+00:23:27,130 --> 00:23:31,810
+utilization هذا بعد النقطة هيك بعد a2 صحيح صار في
+
+312
+00:23:31,810 --> 00:23:33,730
+عندى ال increasing اللى صار في aggregate
+
+313
+00:23:33,730 --> 00:23:38,070
+expenditure زود النتج بس النتج هيرجع يرجع ل y2
+
+314
+00:23:38,070 --> 00:23:44,960
+لأنه في عندى fully crowding outمظبوط؟ و هذا اسمه
+
+315
+00:23:44,960 --> 00:23:48,600
+إذا هيرجع مرة تانية ينزل ال aggregate expenditure
+
+316
+00:23:48,600 --> 00:23:51,380
+من aggregate expenditure تلاتة ل aggregate
+
+317
+00:23:51,380 --> 00:23:55,940
+expenditure اتنين due to the crowding out effect
+
+318
+00:23:55,940 --> 00:23:58,900
+اللي هو ال fully crowding out إذا ال fully
+
+319
+00:23:58,900 --> 00:24:02,460
+crowding out وين رجعني؟ رجعني from aggregate
+
+320
+00:24:02,460 --> 00:24:04,940
+expenditure تلاتة ل aggregate expenditure اتنين
+
+321
+00:24:04,940 --> 00:24:10,860
+إذا وين ال potential GDP في هذا الحلم؟Y2 exactly
+
+322
+00:24:10,860 --> 00:24:15,820
+thank you Y2 صحيح أنا رجعت روحت زدت ل Y3 here but
+
+323
+00:24:15,820 --> 00:24:21,880
+the finally I came back to Y2 هذه المنطقة between
+
+324
+00:24:21,880 --> 00:24:29,420
+E2 to E3 هذه بيسموها ال inflationary gap صح هذه
+
+325
+00:24:29,420 --> 00:24:34,280
+المنطقة هيك او من هنا E2 to E3 is the inflationary
+
+326
+00:24:34,280 --> 00:24:39,510
+gap لأن ال prices طلعت without a change in Yمظبوط؟
+
+327
+00:24:39,510 --> 00:24:47,470
+هل عدم زيادة في ال y نتيجتها إيش؟ أو بسبب شو؟ what
+
+328
+00:24:47,470 --> 00:24:56,510
+are the main causes of .. تمام and .. the
+
+329
+00:24:56,510 --> 00:24:59,330
+multiplier is zero exactly and we have a full
+
+330
+00:24:59,330 --> 00:25:04,660
+crowding outمن مش فاهم اعيدله الشباب اذا لو رجعنا
+
+331
+00:25:04,660 --> 00:25:07,740
+if we come back here this is the original
+
+332
+00:25:07,740 --> 00:25:11,320
+equilibrium point aggregate demand one intersects
+
+333
+00:25:11,320 --> 00:25:16,940
+aggregate supply and here we have a one this is a
+
+334
+00:25:16,940 --> 00:25:24,740
+one and the aggregate output is y one تمامتأثير
+
+335
+00:25:24,740 --> 00:25:30,380
+اقتصادي يؤدي إلى زيادة او تحويل مصطلح الواحد إلى
+
+336
+00:25:30,380 --> 00:25:34,060
+مصطلح المصطلح الثاني مصطلح المصطلح الثاني مصطلح
+
+337
+00:25:34,060 --> 00:25:36,800
+الواحد إلى مصطلح المصطلح الثاني مصطلح الواحد إلى
+
+338
+00:25:36,800 --> 00:25:37,480
+مصطلح المصطلح الثاني مصطلح الواحد إلى مصطلح
+
+339
+00:25:37,480 --> 00:25:38,880
+المصطلح الثاني مصطلح الواحد إلى مصطلح المصطلح
+
+340
+00:25:38,880 --> 00:25:40,540
+الثاني مصطلح الواحد إلى مصطلح المصطلح الثاني مصطلح
+
+341
+00:25:40,540 --> 00:25:42,940
+الواحد إلى مصطلح المصطلح الثاني مصطلح الواحد إلى
+
+342
+00:25:42,940 --> 00:25:51,260
+مصطلح المصطلح الثاني مصط
+
+343
+00:25:53,270 --> 00:25:57,330
+أضافة تجارب تجارب تجارب التحقيق أو تجارب التحقيق
+
+344
+00:25:57,330 --> 00:26:03,650
+أو تجارب التحقيق تجارب تجارب
+
+345
+00:26:03,650 --> 00:26:04,730
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+346
+00:26:04,730 --> 00:26:05,310
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+347
+00:26:05,310 --> 00:26:05,850
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+348
+00:26:05,850 --> 00:26:09,470
+تجارب تجارب تجارب تجارب تج
+
+349
+00:26:12,150 --> 00:26:15,910
+ولكن الانتجار الواضح عندما يتحرك المصادر
+
+350
+00:26:15,910 --> 00:26:24,410
+الانتجارية لـ 2 إلى 3 يعني أو يقوم بإزالة أسعار من
+
+351
+00:26:24,410 --> 00:26:25,490
+P1 إلى P3
+
+352
+00:26:28,350 --> 00:26:31,370
+There is a upward shifting or increasing in the
+
+353
+00:26:31,370 --> 00:26:36,890
+prices without changing Y So Y would decline to YF
+
+354
+00:26:36,890 --> 00:26:42,090
+So YF is what؟ The potential GDP in the long term
+
+355
+00:26:42,090 --> 00:26:46,150
+هذا أقصى حد ممكن يوصل إلى النتجة حتى و لو زاد
+
+356
+00:26:46,150 --> 00:26:51,610
+هيرجع مرة تانية تمام؟
+
+357
+00:26:51,610 --> 00:26:56,430
+هذه المنطقة هيك is inflationary gap لأنه في مجرد
+
+358
+00:26:56,430 --> 00:26:57,370
+زيادات في الأسعار
+
+359
+00:27:00,310 --> 00:27:05,470
+إذا تتذكر في الحلقة الأولى، نحن نتكلم عن مصطلح
+
+360
+00:27:05,470 --> 00:27:11,030
+الانفلاش، وهو ماذا؟ إزالة قيمة الأسعار العامة
+
+361
+00:27:11,030 --> 00:27:14,290
+والإنفلاش
+
+362
+00:27:14,290 --> 00:27:18,410
+المستمرة، كما يحدث عندما تزال قيمة الأسعار العامة
+
+363
+00:27:18,410 --> 00:27:27,880
+ترتفع على بعضها في الوقت طويل،لدينا اثنين نوعين من
+
+364
+00:27:27,880 --> 00:27:32,870
+الاستخدامit's called the demand pull inflation
+
+365
+00:27:32,870 --> 00:27:36,470
+التضخم اللي جاء نتيجة الطلب الطلب بزيد وبتالي
+
+366
+00:27:36,470 --> 00:27:42,730
+عمليا ال prices بتطلع صح؟ شباب we have two types
+
+367
+00:27:42,730 --> 00:27:45,970
+of inflation number one it's called demand pull
+
+368
+00:27:45,970 --> 00:27:49,670
+inflation and the second is cost push inflation or
+
+369
+00:27:49,670 --> 00:27:53,210
+supply side inflation ال demand pull inflation
+
+370
+00:27:53,210 --> 00:27:56,670
+means increasing the aggregate demand which leads
+
+371
+00:27:56,670 --> 00:28:00,920
+to increasing the pricesيعني شو اللي خلّى انه ال
+
+372
+00:28:00,920 --> 00:28:03,820
+aggregate demand يزيد او شو اللي خلّى ال prices
+
+373
+00:28:03,820 --> 00:28:06,700
+تزيد ال inflation يزيد ال aggregate demand
+
+374
+00:28:06,700 --> 00:28:10,460
+increase maybe by using as a result or due to the
+
+375
+00:28:10,460 --> 00:28:12,840
+expansion policy or expansion fiscal or
+
+376
+00:28:12,840 --> 00:28:16,600
+expansionary monetary policy right؟ what about the
+
+377
+00:28:16,600 --> 00:28:22,040
+cost push inflation؟ شو سبب انه ال prices طلع؟
+
+378
+00:28:22,040 --> 00:28:26,990
+increasing the cost of productionمصبوط؟ لـ
+
+379
+00:28:26,990 --> 00:28:29,210
+increasing the cost of production like increasing
+
+380
+00:28:29,210 --> 00:28:32,290
+the prices of inputs to increase the wages leads
+
+381
+00:28:32,290 --> 00:28:36,150
+to what? leads to decrease the .. exactly the
+
+382
+00:28:36,150 --> 00:28:39,590
+prices would increase تمام؟ so we have a leftward
+
+383
+00:28:39,590 --> 00:28:42,690
+shifting in the aggregate supply curve which means
+
+384
+00:28:42,690 --> 00:28:46,490
+increasing the prices from .. we have a .. a new
+
+385
+00:28:46,490 --> 00:28:48,990
+equilibrium point from A1 to A2 which means
+
+386
+00:28:48,990 --> 00:28:53,270
+increasing the prices from A note .. P note to P1
+
+387
+00:28:53,520 --> 00:28:55,980
+لذالك لدينا اتفاقين اتفاقين اتفاقين اتفاقين
+
+388
+00:28:55,980 --> 00:29:01,420
+اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين
+
+389
+00:29:01,420 --> 00:29:05,840
+اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين
+
+390
+00:29:05,840 --> 00:29:06,160
+اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين
+
+391
+00:29:06,160 --> 00:29:06,220
+اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين
+
+392
+00:29:06,220 --> 00:29:11,540
+اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين
+
+393
+00:29:11,540 --> 00:29:18,860
+اتفاقين اتفاقين ا
+
+394
+00:29:21,210 --> 00:29:27,230
+بالضبط لدينا إزالة الأسعار أو الإنفلاش وإزالة
+
+395
+00:29:27,230 --> 00:29:36,190
+عمليات العمليات في نفس الوقت كما
+
+396
+00:29:36,190 --> 00:29:40,870
+ذكرنا قبل عندما
+
+397
+00:29:40,870 --> 00:29:44,630
+كان الحكومة
+
+398
+00:29:44,630 --> 00:29:49,530
+تستخدم حكومة عمليات العمليات هذا يدفع إلى إزالة
+
+399
+00:29:49,530 --> 00:29:55,170
+عمليات العملياتلنقوم بعمل تجارب تجارب تجارب تجارب
+
+400
+00:29:55,170 --> 00:30:02,130
+تجارب تجارب
+
+401
+00:30:02,130 --> 00:30:04,870
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+402
+00:30:04,870 --> 00:30:05,130
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+403
+00:30:05,130 --> 00:30:05,210
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+404
+00:30:05,210 --> 00:30:20,510
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب ت
+
+405
+00:30:21,520 --> 00:30:32,360
+aggregate demand one one a one p one y one this is
+
+406
+00:30:32,360 --> 00:30:34,760
+prices y
+
+407
+00:30:36,520 --> 00:30:40,680
+هذه هي الوصولة الآن فاعتبار أن الحكومة استخدمت
+
+408
+00:30:40,680 --> 00:30:45,520
+تنفيذ تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+409
+00:30:45,520 --> 00:30:45,680
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+410
+00:30:45,680 --> 00:30:45,820
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+411
+00:30:45,820 --> 00:30:46,500
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+412
+00:30:46,500 --> 00:30:46,940
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+413
+00:30:46,940 --> 00:30:47,420
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+414
+00:30:47,420 --> 00:30:47,500
+تجارب تجارب
+
+415
+00:31:05,470 --> 00:31:15,770
+هذا هو اي اتو عندما تزال السعر يزال يزال يزال يزال
+
+416
+00:31:15,770 --> 00:31:17,150
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزل
+
+417
+00:31:17,150 --> 00:31:21,490
+يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل
+
+418
+00:31:21,490 --> 00:31:21,890
+يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل
+
+419
+00:31:21,890 --> 00:31:25,370
+يزل يزل يزل يزل يزل يزل يزل يDecrease Aggregate
+
+420
+00:31:25,370 --> 00:31:31,390
+Supply لذلك هناك اتفاق اتفاق اتفاق اتفاق اتفاق
+
+421
+00:31:31,390 --> 00:31:38,690
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+422
+00:31:38,690 --> 00:31:40,530
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+423
+00:31:40,530 --> 00:31:41,450
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+424
+00:31:41,450 --> 00:31:41,530
+اتفاق اتفاق اتفاق اتفاق اتفاق
+
+425
+00:31:55,820 --> 00:31:59,260
+هل ال increasing في ال prices from P1 to P2 to P3
+
+426
+00:31:59,260 --> 00:32:03,940
+شو اسمه هذا؟ Inflation طيب ال decreasing اللي صار
+
+427
+00:32:03,940 --> 00:32:07,940
+في ال aggregate output هذا تخفيض النترية شو معناه؟
+
+428
+00:32:07,940 --> 00:32:13,120
+ان البطالي زادت exactly exactly إذا هذا ال
+
+429
+00:32:13,120 --> 00:32:19,640
+increasing في ال prices from P1 to P3 شو معناه؟
+
+430
+00:32:19,640 --> 00:32:25,040
+Inflation at the same time yes
+
+431
+00:32:27,650 --> 00:32:31,150
+الزيارة طبعا ال Y، بس لما لاحظت ال 3 طب بلجأ ال Y،
+
+432
+00:32:31,150 --> 00:32:34,510
+كيف صارت هذا؟ ال rejoin اللي صار في ال Y هذا، شو
+
+433
+00:32:34,510 --> 00:32:37,890
+معناه from Y2 to Y3؟ إن ال cost of production طلع
+
+434
+00:32:38,750 --> 00:32:42,290
+صار في عندك cost push inflation او supply side
+
+435
+00:32:42,290 --> 00:32:45,790
+inflation شو اللي صار الارتفاع اللي صار في الأسعار
+
+436
+00:32:45,790 --> 00:32:49,830
+شو عمل increased في ال wages مظبوط زيادة في ال
+
+437
+00:32:49,830 --> 00:32:52,230
+wages شو عملت في ال cost of production زودت ال
+
+438
+00:32:52,230 --> 00:32:56,070
+cost of production وبالتالي ال ability تبع ال
+
+439
+00:32:56,070 --> 00:32:59,090
+producers انه ينتجوا more and more would decline
+
+440
+00:32:59,090 --> 00:33:02,210
+وبالتالي aggregate supply would decline so there
+
+441
+00:33:02,210 --> 00:33:05,470
+is a backward shifting او a leftward shifting في
+
+442
+00:33:05,470 --> 00:33:07,210
+ال aggregate supply curve from aggregate supply
+
+443
+00:33:07,210 --> 00:33:12,250
+one to aggregate supply twoطيب شو عمل هذا؟ this is
+
+444
+00:33:12,250 --> 00:33:15,750
+a3 شو اللي عمل؟ عملنا backward shifting في ال
+
+445
+00:33:15,750 --> 00:33:20,630
+aggregate supply، ال prices طلعت و ال Y نزل، هلأ
+
+446
+00:33:20,630 --> 00:33:23,890
+ال increasing في ال prices شو معناه؟ what is the
+
+447
+00:33:23,890 --> 00:33:27,150
+meaning of increasing the prices؟ inflation، plus
+
+448
+00:33:27,150 --> 00:33:31,790
+ال decreasing اللي صار في ال Y from Y2 to Y3
+
+449
+00:33:34,370 --> 00:33:36,630
+النتج لما بنزل، شو بيصير في ال unemployment؟
+
+450
+00:33:36,630 --> 00:33:38,710
+معناه، this means ان ال unemployment rate
+
+451
+00:33:38,710 --> 00:33:42,970
+increased، so this means ان we have increasing in
+
+452
+00:33:42,970 --> 00:33:48,750
+the unemployment rate which is a stagnation،
+
+453
+00:33:48,750 --> 00:33:52,690
+واضحة؟ اذا ال stagnation means increasing in the
+
+454
+00:33:52,690 --> 00:33:55,010
+price .. in the overall price levels and
+
+455
+00:33:55,010 --> 00:34:00,070
+increasing and .. for the unemployment at the same
+
+456
+00:34:00,070 --> 00:34:07,620
+time، تمام؟مين اعيدله مش وانا فاهم اوضحله اشي تمام
+
+457
+00:34:07,620 --> 00:34:17,500
+okay yes yes the potential is no y3 ال potential
+
+458
+00:34:17,500 --> 00:34:22,340
+GDP is y3 هذا potential with inflation potential
+
+459
+00:34:22,340 --> 00:34:28,900
+without inflation y1صح؟ بظبط لأنه الناتج هنا
+
+460
+00:34:28,900 --> 00:34:32,880
+increased and then declined and this is in the
+
+461
+00:34:32,880 --> 00:34:48,800
+long term طيب
+
+462
+00:34:48,800 --> 00:34:52,760
+اوك كده change الله تعالى .. okay
+
+463
+00:35:02,320 --> 00:35:09,480
+Expectation and inflation شو
+
+464
+00:35:09,480 --> 00:35:12,880
+الإلاقة ما بين ال expectation about the future أو
+
+465
+00:35:12,880 --> 00:35:16,600
+expectation about something and inflation ال
+
+466
+00:35:16,600 --> 00:35:21,740
+expectations about the changes and future prices
+
+467
+00:35:21,740 --> 00:35:26,120
+may affect current decisions إذا أنا بتوقع أن
+
+468
+00:35:26,120 --> 00:35:28,620
+الأسعار هترتفع خلال الفترة الجاية شو اللي بيعمل؟
+
+469
+00:35:28,620 --> 00:35:32,860
+شو اللي بيصير عنداه؟الـ firms may raise their
+
+470
+00:35:32,860 --> 00:35:36,320
+prices in expectation of competitors doing and the
+
+471
+00:35:36,320 --> 00:35:39,520
+competitors will do the same، إذا مؤسسة بتتوقع
+
+472
+00:35:39,520 --> 00:35:43,020
+أنها الأسعار بتطلع و حدا راح رفع الأسعار، الكل
+
+473
+00:35:43,020 --> 00:35:45,520
+برفع الأسعار، هذا واحد، مظبوط؟
+
+474
+00:35:53,900 --> 00:36:00,160
+العمال اللي بتوقعه
+
+475
+00:36:00,160 --> 00:36:04,740
+العمال اللي بتوقعه ان ال prices هتطلع يروح يطلبوا
+
+476
+00:36:04,740 --> 00:36:05,620
+أجور أعلى
+
+477
+00:36:15,520 --> 00:36:18,860
+مش هو الـ hyperinflation؟ الـ rapid increase in
+
+478
+00:36:18,860 --> 00:36:22,060
+the overall price levels in the long term، بصبح؟
+
+479
+00:36:22,060 --> 00:36:27,580
+quickly، ال prices بتطلع بسرعة، so here as you see
+
+480
+00:36:27,580 --> 00:36:31,480
+the equilibrium occurs when aggregate demand does
+
+481
+00:36:31,480 --> 00:36:34,880
+not intersect the aggregate supply، سببوز إنه في
+
+482
+00:36:34,880 --> 00:36:40,900
+عندنا expenditure fiscal policy، the increasing in
+
+483
+00:36:40,900 --> 00:36:50,740
+government spendingwith or without a change and
+
+484
+00:36:50,740 --> 00:36:55,760
+monitor policy شوف
+
+485
+00:36:55,760 --> 00:37:00,460
+تعمل increase aggregate demand so there is a right
+
+486
+00:37:00,460 --> 00:37:04,840
+word shifting and aggregate demand curve تمام شوف
+
+487
+00:37:04,840 --> 00:37:07,520
+سيف ال prices would increase اعمل كمان مرة
+
+488
+00:37:07,520 --> 00:37:10,460
+increasing في ال aggregate demand to aggregate
+
+489
+00:37:10,460 --> 00:37:14,460
+demand two increasing aggregate demand three so
+
+490
+00:37:15,890 --> 00:37:21,590
+لدينا إزالة عالية في مقاومة الأسعار العامة بسبب
+
+491
+00:37:21,590 --> 00:37:24,750
+إزالة
+
+492
+00:37:24,750 --> 00:37:27,450
+مقاومة الأسعار العامة بسبب إزالة مقاومة الأسعار
+
+493
+00:37:27,450 --> 00:37:28,370
+العامة بسبب إزالة مقاومة الأسعار العامة بسبب إزالة
+
+494
+00:37:28,370 --> 00:37:32,810
+مقاومة الأسعار العامة بسبب إزالة مقاومة الأسعار
+
+495
+00:37:32,810 --> 00:37:36,230
+العامة بسبب إزالة مقاومة الأسعار العامة بسبب إزالة
+
+496
+00:37:36,230 --> 00:37:38,630
+مقاومة الأسعار العامة بسبب إزالة مقاومة الأسعار
+
+497
+00:37:38,630 --> 00:37:39,370
+العامة بسبب إزالة مقاومة الأسعار العامة بسبب إزالة
+
+498
+00:37:39,370 --> 00:37:44,970
+مقاومة الأسعار العامة بسبب إزالة
+
+499
+00:37:44,970 --> 00:37:47,800
+مقاومالـ Increasing in the governance funding شو
+
+500
+00:37:47,800 --> 00:37:51,640
+عمل؟ Without a change في الـ Monetary Policy شو
+
+501
+00:37:51,640 --> 00:37:53,880
+عمل؟ Increased aggregate demand أو aggregate
+
+502
+00:37:53,880 --> 00:37:57,560
+expenditure مظبوط Which leads to increasing Y
+
+503
+00:37:57,560 --> 00:38:03,000
+Increased money demand Increased
+
+504
+00:38:03,000 --> 00:38:07,500
+R إذن هذا شو عمل؟ Increasing في الـR واللي عمل
+
+505
+00:38:07,500 --> 00:38:10,580
+Decreasing في الـI وهذا اسمه The crowding out So
+
+506
+00:38:10,580 --> 00:38:14,290
+the crowding out would increaseبصبوح هذا ال
+
+507
+00:38:14,290 --> 00:38:25,450
+analysis تبع ال diagram هذا نفس
+
+508
+00:38:25,450 --> 00:38:31,200
+ال the sameوالـ slide بيقول إنه an increase in the
+
+509
+00:38:31,200 --> 00:38:34,600
+government spending with money supply constants
+
+510
+00:38:34,600 --> 00:38:36,920
+will shift the aggregate demand curve from
+
+511
+00:38:36,920 --> 00:38:40,160
+aggregate demand one to aggregate demand two and
+
+512
+00:38:40,160 --> 00:38:44,440
+so on although not shown in the figure this leads
+
+513
+00:38:44,440 --> 00:38:47,300
+to an increase in the interest rate ده اللي حللناه
+
+514
+00:38:47,300 --> 00:38:50,060
+وبالتالي ال crowding out would increase ال
+
+515
+00:38:50,060 --> 00:38:52,140
+crowding out in the planned investment would
+
+516
+00:38:52,140 --> 00:38:57,140
+increaseطب خليني أشوف أنه suppose there is a
+
+517
+00:38:57,140 --> 00:39:00,120
+change in the money supply or the monetary policy
+
+518
+00:39:00,120 --> 00:39:07,740
+what would happen؟
+
+519
+00:39:09,940 --> 00:39:13,940
+هلأ without a change شو عمل؟ عملنا hyperinflation
+
+520
+00:39:13,940 --> 00:39:18,360
+if the money supply remains constant without a
+
+521
+00:39:18,360 --> 00:39:21,420
+change يعني ماغيروش .. يأثروا على سعر الفائدة
+
+522
+00:39:21,420 --> 00:39:24,880
+suppose we use an exponential fiscal policy، تمام،
+
+523
+00:39:24,880 --> 00:39:28,320
+هذا شو عمل؟ رفع ال interest rate، صح؟ وخلق مشكلة
+
+524
+00:39:28,320 --> 00:39:32,400
+crowding out، أظبط ولا لأ؟ هلأ ال prices شو بيصير
+
+525
+00:39:32,400 --> 00:39:36,950
+فيها؟ كل ما بيزيدالـ .. الـ government spending ال
+
+526
+00:39:36,950 --> 00:39:39,830
+aggregate demand would increase which means we
+
+527
+00:39:39,830 --> 00:39:42,970
+have a rapid increasing in the price levels،
+
+528
+00:39:42,970 --> 00:39:46,970
+مظبوط؟ هذا without intervention by the central
+
+529
+00:39:46,970 --> 00:39:49,850
+bank to increase the money supply، اللي بنتش نلغي
+
+530
+00:39:49,850 --> 00:39:55,230
+without اللي هو الغاء .. بدون الغاء أثر ال
+
+531
+00:39:55,230 --> 00:39:58,780
+interest rate على ال investmentطب خلينا نشوف لو
+
+532
+00:39:58,780 --> 00:40:01,940
+راحوا عاملين راحوا ال central bank مزود ال money
+
+533
+00:40:01,940 --> 00:40:05,040
+supply يعني صارت في عنده increasing هنا في ال
+
+534
+00:40:05,040 --> 00:40:08,000
+aggregate demand from aggregate demand no to
+
+535
+00:40:08,000 --> 00:40:11,160
+aggregate demand one to two to three خلينا without
+
+536
+00:40:11,160 --> 00:40:14,320
+it change ال money supply بس خلينا نشوف انهم راحوا
+
+537
+00:40:14,320 --> 00:40:18,240
+بدهم يلغوا تأثير ال Rأحنا مشكلتنا في الـ crowding
+
+538
+00:40:18,240 --> 00:40:22,500
+out وين؟ إنه الـ interest rate طلع وبتتمنى نزل الـ
+
+539
+00:40:22,500 --> 00:40:24,720
+aggregate لـ planned investment وبتنهي نزل ال Y،
+
+540
+00:40:24,720 --> 00:40:29,020
+صح؟ هلقيت؟ خلّيني نشوف إنه عشان يلغوا تأثير الـ R،
+
+541
+00:40:29,020 --> 00:40:33,300
+شغلنا بنعمل في الـ monosupply؟ نحتاج لإزالة الـ
+
+542
+00:40:33,300 --> 00:40:36,380
+monosupply، فلأ إذا بتذكروا، إذا بتذكروا، عشان
+
+543
+00:40:36,380 --> 00:40:40,200
+نلغوا موضوع الـ crowding out، لازم نعمل شو؟ نزود
+
+544
+00:40:40,200 --> 00:40:43,600
+الـ monosupply، لأن الإشكال يوين كانت عندنا، خليني
+
+545
+00:40:43,600 --> 00:40:46,360
+أرجحكم شوية لموضوع الـ monosupply و الـ monodemand
+
+546
+00:40:50,060 --> 00:40:55,280
+this is the money supply one money demand one هذا
+
+547
+00:40:55,280 --> 00:40:58,040
+بدأ أرجعكم شويه عشان قبل ما أفوت على النقطة هاي
+
+548
+00:40:58,040 --> 00:41:07,540
+this is E one R one AQM one تمام هلأ في الحالة هذه
+
+549
+00:41:07,540 --> 00:41:10,160
+increasing the government spending شو عملني؟ عملنا
+
+550
+00:41:10,160 --> 00:41:12,560
+increasing في ال money demand وبالتالي there is a
+
+551
+00:41:12,560 --> 00:41:15,820
+rightward shifting in the money demand curve صح؟
+
+552
+00:41:15,820 --> 00:41:21,280
+شو يعمل فيه؟تقوم ديتو رافع ال interest rate from
+
+553
+00:41:21,280 --> 00:41:26,580
+R1 to R2 صح؟ وهذا اللي عمللي مشكلة crowding out،
+
+554
+00:41:26,580 --> 00:41:29,620
+بصبوط؟ صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح،
+
+555
+00:41:29,620 --> 00:41:29,780
+صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح،
+
+556
+00:41:29,780 --> 00:41:31,300
+صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح،
+
+557
+00:41:31,300 --> 00:41:35,280
+صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح،
+
+558
+00:41:35,280 --> 00:41:37,840
+صح، صح،
+
+559
+00:41:45,660 --> 00:41:49,040
+عشان ألغى التأثير لازم أزود ال money supply فخلينا
+
+560
+00:41:49,040 --> 00:41:53,740
+نشوف if the central bank or the federal reserve
+
+561
+00:41:53,740 --> 00:41:58,240
+system in this case used an expansionary monitor
+
+562
+00:41:58,240 --> 00:42:00,580
+policy by increasing the money supply شو اللي
+
+563
+00:42:00,580 --> 00:42:05,020
+بيصير في ال prices؟
+
+564
+00:42:05,020 --> 00:42:09,540
+خلينا نشوف yes مين عندهم؟ yes محمد you have؟ طيب
+
+565
+00:42:09,540 --> 00:42:16,220
+so let's useأو دعنا نعتمد على أن الشركة الأساسية
+
+566
+00:42:16,220 --> 00:42:24,720
+استعملت قياسية تدخلية تدخل الأموال بإزالة تدخل
+
+567
+00:42:24,720 --> 00:42:28,180
+الأموال لتغيير
+
+568
+00:42:28,180 --> 00:42:36,380
+تأثير تدخل الأموال بإزالة تدخل الأموال بإزالة تدخل
+
+569
+00:42:36,380 --> 00:42:37,900
+الأموال لتغيير تدخل الأموال
+
+570
+00:42:44,480 --> 00:42:48,920
+decrease in the interest rate increase I increase
+
+571
+00:42:48,920 --> 00:42:52,940
+aggregate expenditure or increase aggregate demand
+
+572
+00:42:52,940 --> 00:42:55,700
+so in this case the aggregate demand would
+
+573
+00:42:55,700 --> 00:43:01,080
+increase once again شو اللي حيصير؟ the prices
+
+574
+00:43:01,080 --> 00:43:05,900
+would increase hyperinflation exactly يا بقى
+
+575
+00:43:05,900 --> 00:43:09,940
+hyperinflation اذا بعد ال full capacity هذا هيك
+
+576
+00:43:11,730 --> 00:43:15,870
+بيكون أصلا ال .. ال .. ال .. ال fiscal policy
+
+577
+00:43:15,870 --> 00:43:18,490
+neither the fiscal policy nor the monetary policy
+
+578
+00:43:18,490 --> 00:43:23,410
+is effective صح؟ لأنه خربوا الدنيا هيك، مظبوط ولا
+
+579
+00:43:23,410 --> 00:43:28,230
+لأ؟ لأنه خربت هيك، لأنه زيادات اللي صارت في ال
+
+580
+00:43:28,230 --> 00:43:30,370
+fiscal policy، ال expansion of fiscal policy، شو
+
+581
+00:43:30,370 --> 00:43:32,690
+عملتوا ال prices؟ طلعتوا، وال expansion of
+
+582
+00:43:32,690 --> 00:43:37,770
+monetary policy increased the prices صح؟ واضحة ولا
+
+583
+00:43:37,770 --> 00:43:41,830
+فيها مشاكل؟إيه؟ طب مين حابب يعيدله الجزئية
+
+584
+00:43:41,830 --> 00:43:47,950
+والموضوع هذا؟ إذا if the federal الحل إنه يرجع
+
+585
+00:43:47,950 --> 00:43:53,730
+لوين إنه إذا كنا بعد ال full capacity المفروض إنه
+
+586
+00:43:53,730 --> 00:43:56,230
+ماستخدمش expansion of fiscal ولا expansion of
+
+587
+00:43:56,230 --> 00:44:04,910
+monetary policy شوف
+
+588
+00:44:04,910 --> 00:44:11,390
+no .. no .. no .. no ..يعني the increasing the
+
+589
+00:44:11,390 --> 00:44:14,250
+government spending is ineffective, so they will
+
+590
+00:44:14,250 --> 00:44:20,770
+spend money without effects, without impacts on
+
+591
+00:44:20,770 --> 00:44:21,290
+the economy
+
+592
+00:44:24,260 --> 00:44:30,320
+وهو ممكن يخلق مقاومة في الميزانية ويخلق زيادة في
+
+593
+00:44:30,320 --> 00:44:34,740
+ميزانية الانفلات بدون امبارحات بدون امبارحات
+
+594
+00:44:34,740 --> 00:44:34,760
+امبارحات امبارحات امبارحات امبارحات امبارحات
+
+595
+00:44:34,760 --> 00:44:37,920
+امبارحات امبارحات امبارحات امبارحات
+
+596
+00:44:39,930 --> 00:44:43,650
+The interest rate on a change by increasing the
+
+597
+00:44:43,650 --> 00:44:46,690
+money supply هذا التحليل اللي عملناه الجد انه بدون
+
+598
+00:44:46,690 --> 00:44:49,330
+ميثابته سعر الفائدة by increasing the money supply
+
+599
+00:44:49,330 --> 00:44:53,430
+the aggregate demand curve will shift further and
+
+600
+00:44:53,430 --> 00:44:56,950
+further to the right the result would be a
+
+601
+00:44:56,950 --> 00:45:01,430
+sustained inflation اللي هو sustained inflation or
+
+602
+00:45:01,430 --> 00:45:04,230
+hyperinflation يعطيكم العافية
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/5La1lkc1hBw_raw.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/5La1lkc1hBw_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..09e70373f9bded844fbd72d3334a9e38b149db44
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/5La1lkc1hBw_raw.srt
@@ -0,0 +1,2496 @@
+1
+00:00:20,670 --> 00:00:21,390
+السلام عليكم ورحمة الله ورحمة الله ورحمة الله
+
+2
+00:00:21,390 --> 00:00:23,970
+ورحمة الله ورحمة الله ورحمة الله ورحمة الله ورحمة
+
+3
+00:00:23,970 --> 00:00:24,850
+الله ورحمة الله ورحمة الله ورحمة الله ورحمة الله
+
+4
+00:00:24,850 --> 00:00:27,250
+ورحمة الله ورحمة الله ورحمة الله ورحمة الله ورحمة
+
+5
+00:00:27,250 --> 00:00:30,770
+الله ورحمة الله ورحمة الله ورحمة الله ورحمة الله
+
+6
+00:00:30,770 --> 00:00:42,970
+ورحمة الله ورحمة
+
+7
+00:00:42,970 --> 00:00:46,790
+الله ورحمة
+
+8
+00:00:46,790 --> 00:00:52,970
+اللهوالـ GDP المميز في الوقت طويل وفي الوقت قصير
+
+9
+00:00:52,970 --> 00:00:57,710
+كما تشاهد في هذا البرنامج، لدينا الـ Equilibrium
+
+10
+00:00:57,710 --> 00:01:01,710
+هذا هو المساعدة الأساسية الأساسية الأساسية
+
+11
+00:01:01,710 --> 00:01:04,170
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+12
+00:01:04,170 --> 00:01:05,170
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+13
+00:01:05,170 --> 00:01:05,170
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+14
+00:01:05,170 --> 00:01:06,070
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+15
+00:01:06,070 --> 00:01:12,230
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+16
+00:01:12,230 --> 00:01:17,350
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+17
+00:01:17,350 --> 00:01:17,350
+الأساسية الأساسية الأساسية الأساسية الأساسية
+
+18
+00:01:17,350 --> 00:01:18,180
+الأساسية الأساسية الأساسية الأساسية الأساسيةكما
+
+19
+00:01:18,180 --> 00:01:24,900
+ذكرنا أن إذا كانت الحكومة تستخدم حكومة اتفاقية او
+
+20
+00:01:24,900 --> 00:01:27,800
+حكومة مالية اتفاقية أو مالية اتفاقية أو مالية
+
+21
+00:01:27,800 --> 00:01:27,820
+اتفاقية أو مالية اتفاقية أو مالية اتفاقية أو مالية
+
+22
+00:01:27,820 --> 00:01:27,820
+اتفاقية أو مالية اتفاقية أو مالية اتفاقية أو مالية
+
+23
+00:01:27,820 --> 00:01:29,940
+اتفاقية أو مالية اتفاقية أو مالية اتفاقية او مالية
+
+24
+00:01:29,940 --> 00:01:34,560
+اتفاقية او مالية اتفاقية او مالية اتفاقية او مالية
+
+25
+00:01:34,560 --> 00:01:39,100
+اتفاقية اتفاقية او مالية اتفاقية اتفاقية اتفاقية
+
+26
+00:01:39,100 --> 00:01:42,940
+اتفاقية ات
+
+27
+00:01:44,940 --> 00:01:48,900
+تحول إلى كلمة صحيحة وطرق مطالبة المطالبة من مطالبة
+
+28
+00:01:48,900 --> 00:01:54,200
+المطالبة 1 إلى مطالبة المطالبة 2 وهو يعني أننا
+
+29
+00:01:54,200 --> 00:02:00,560
+لدينا نقطة ايقاليبريان جديدة هنا اي وان اي اتو
+
+30
+00:02:00,560 --> 00:02:07,760
+الأسعار كانت تزيد من نقطة P1 إلى P2 في هذه الحالة
+
+31
+00:02:07,760 --> 00:02:13,180
+يزيد Y من Y1 إلى Y2
+
+32
+00:02:18,120 --> 00:02:23,700
+عندما يزال السعر يزال يزال يزال يزال يزال يزال
+
+33
+00:02:23,700 --> 00:02:28,430
+يزالالتحويل إلى تحويل الحكومة، فهنا نتحدث عن تحويل
+
+34
+00:02:28,430 --> 00:02:33,050
+الحكومة، رغم أنه يكون مالي أو فسكت، فهذا يؤدي إلى
+
+35
+00:02:33,050 --> 00:02:36,570
+تحويل
+
+36
+00:02:36,570 --> 00:02:42,170
+المساعدة المالية، يؤدي إلى تحويل R، تحويل I،
+
+37
+00:02:42,170 --> 00:02:44,530
+تحويل، تحويل المساعدة التجارية أو التحويل التجارية
+
+38
+00:02:46,720 --> 00:02:49,080
+لذلك Y ستزال يزال يزال يزال يزال يزال يزال يزال
+
+39
+00:02:49,080 --> 00:02:53,840
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+40
+00:02:53,840 --> 00:02:56,160
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+41
+00:02:56,160 --> 00:03:01,780
+يزال يزال يزال
+
+42
+00:03:01,780 --> 00:03:01,920
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+43
+00:03:01,920 --> 00:03:02,240
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+44
+00:03:02,240 --> 00:03:02,280
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+45
+00:03:02,280 --> 00:03:03,440
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+46
+00:03:03,440 --> 00:03:05,560
+يزال يزال
+
+47
+00:03:16,340 --> 00:03:23,360
+وهذا يعني اتقال في المصادر المجاورة، فهناك تحويل
+
+48
+00:03:23,360 --> 00:03:27,880
+مجاور للأعلى ومجاورة المصادر المجاورة، فهناك تحويل
+
+49
+00:03:27,880 --> 00:03:33,340
+مجاور للأعلى من المصادر المجاورة 1 إلى المصادر
+
+50
+00:03:33,340 --> 00:03:38,700
+المجاورة 2بالتالي، في هذه الحالة، ستزداد الأسعار
+
+51
+00:03:38,700 --> 00:03:46,300
+من P2 إلى P3، وY ستتخلص من Y2 إلى Y1، وهو الـ GDP
+
+52
+00:03:46,300 --> 00:03:47,360
+الممكنة
+
+53
+00:03:55,190 --> 00:04:00,350
+لذلك كما ترى هناك تغيير للمساعدة التجارية من
+
+54
+00:04:00,350 --> 00:04:04,010
+المساعدة التجارية 1 إلى 2 مما يعني أنه يزيد
+
+55
+00:04:04,010 --> 00:04:10,340
+السعوديين، لكن ماهو أفضل لنا؟ لماذا 1؟without
+
+56
+00:04:10,340 --> 00:04:14,840
+increasing the prices or y1 here is the potential
+
+57
+00:04:14,840 --> 00:04:19,460
+GDP يعني أقصى حاجة ممكن نوصلها هو y1 صحيح أن ال y1
+
+58
+00:04:19,460 --> 00:04:22,400
+increase بعدين then decrease which is better for
+
+59
+00:04:22,400 --> 00:04:28,280
+us for the economy y1 without increasing the
+
+60
+00:04:28,280 --> 00:04:32,800
+prices or without inflation or y1 with inflation
+
+61
+00:04:32,800 --> 00:04:39,200
+without inflation exactlyY1 هنا في الواقع الأول في
+
+62
+00:04:39,200 --> 00:04:47,320
+الـ A1 يسمى الـ GDP الممكنة بدون الإنفلاش Y1 هنا
+
+63
+00:04:47,320 --> 00:04:52,040
+إذا ارتفع التطبيق التجاري و بعد ذلك تتخلص التطبيق
+
+64
+00:04:52,040 --> 00:04:58,360
+التجاري هذا يعني أننا سنصل أو سنعود إلى القدرة أو
+
+65
+00:04:58,360 --> 00:05:02,880
+استخدام القدرة التجارية أو GDP الممكنة ولكن لدينا
+
+66
+00:05:02,880 --> 00:05:08,180
+ارتفاع الأسعاروهذا يعني أننا لدينا GDP ممكنة مع
+
+67
+00:05:08,180 --> 00:05:11,980
+زيادة الأسعار بدون تغيير في الوصول الانتجاري،
+
+68
+00:05:11,980 --> 00:05:18,660
+ويعني GDP ممكنة مع تغيير الانتجار، لذلك نحن سنفضر
+
+69
+00:05:18,660 --> 00:05:28,000
+أن نعمل في Y1 بدون تغيير الانتجار، صح؟و اذا وصلنا
+
+70
+00:05:28,000 --> 00:05:32,860
+احنا اصلا ل A1 هنا خلاص مش لازم ان انا اروح اعمل
+
+71
+00:05:32,860 --> 00:05:36,840
+increasing of money supply او using an
+
+72
+00:05:36,840 --> 00:05:42,380
+expansionary fiscal or monetary policyالتحويل من
+
+73
+00:05:42,380 --> 00:05:49,580
+تحويل الأسعار إلى تحويل الأسعار ثم تحويل الأسعار
+
+74
+00:05:49,580 --> 00:05:51,560
+إلى تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+75
+00:05:51,560 --> 00:05:51,700
+الأسعار ثم تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+76
+00:05:51,700 --> 00:05:51,760
+الأسعار ثم تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+77
+00:05:51,760 --> 00:05:51,940
+الأسعار ثم تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+78
+00:05:51,940 --> 00:05:52,100
+الأسعار ثم تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+79
+00:05:52,100 --> 00:05:56,420
+الأسعار ثم تحويل الأسعار ثم تحويل الأسعار ثم تحويل
+
+80
+00:05:56,420 --> 00:06:06,640
+الأسعار ثم تحويل الأسعار ثم
+
+81
+00:06:06,830 --> 00:06:12,550
+وما هو أفضل بالنسبة لي A1 او A3؟ A1 أفضل من A3 لأن
+
+82
+00:06:12,550 --> 00:06:18,390
+A1 يعني أنني سأصبح في Y1، صحيح؟ الوصول المجلدية
+
+83
+00:06:18,390 --> 00:06:27,810
+سيكون Y1 بقيمة P1 ولكن A3 يعني نفس الوصول المجلدية
+
+84
+00:06:27,810 --> 00:06:35,410
+بقيمة أعلى، مظبوط؟ لنذهب إلى مشكلة أخرى
+
+85
+00:06:49,710 --> 00:06:56,150
+كما ذكرنا سابقًا، نستطيع
+
+86
+00:06:56,150 --> 00:06:57,990
+ان نقوم باستخدام مجموعة تدفع مجموعة تدفع مجموعة
+
+87
+00:06:57,990 --> 00:06:58,830
+تدفع مجموعة تدفع مجموعة تدفع مجموعة تدفع مجموعة
+
+88
+00:06:58,830 --> 00:06:59,230
+تدفع مجموعة تدفع مجموعة تدفع مجموعة تدفع مجموعة
+
+89
+00:06:59,230 --> 00:07:00,190
+تدفع مجموعة تدفع مجموعة تدفع مجموعة تدفع مجموعة
+
+90
+00:07:00,190 --> 00:07:00,830
+تدفع مجموعة تدفع مجموعة تدفع مجموعة تدفع مجموعة
+
+91
+00:07:00,830 --> 00:07:18,470
+تدفع مجموعة تدفع مجموعة تدفع مجموعة تدفع م
+
+92
+00:07:18,580 --> 00:07:22,900
+في الفترة الصغيرة أو الفترة الصغيرة للغاية إذا كنا
+
+93
+00:07:22,900 --> 00:07:27,720
+نستخدم قرار اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+94
+00:07:27,720 --> 00:07:28,520
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+95
+00:07:28,520 --> 00:07:32,440
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+96
+00:07:32,440 --> 00:07:32,500
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+97
+00:07:32,500 --> 00:07:33,000
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+98
+00:07:33,000 --> 00:07:33,000
+اتفاق
+
+99
+00:07:47,740 --> 00:07:52,800
+إذا استخدمنا قياسية اتفاق أو قياسية اتفاق اتفاق
+
+100
+00:07:52,800 --> 00:07:55,620
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+101
+00:07:55,620 --> 00:07:59,460
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+102
+00:07:59,460 --> 00:08:03,640
+اتفاق اتفاق اتفاق اتفاق اتفاق
+
+103
+00:08:03,640 --> 00:08:05,420
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+104
+00:08:05,420 --> 00:08:06,320
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+105
+00:08:06,320 --> 00:08:17,530
+اتفاق اتفاincreasing from Y to Y0 to Y1 مصبوط؟ مين
+
+106
+00:08:17,530 --> 00:08:21,210
+اللي تتغير فيه أعلى؟ الـY أو الـPrices؟ الـY،
+
+107
+00:08:21,210 --> 00:08:23,490
+الـY، الـY، الـY، الـY، الـY، الـY، الـY، الـY،
+
+108
+00:08:23,490 --> 00:08:24,190
+الـY، الـY، الـY، الـY، الـY، الـY، الـY، الـY،
+
+109
+00:08:24,190 --> 00:08:25,550
+الـY، الـY، الـY، الـY، الـY، الـY، الـY، الـY،
+
+110
+00:08:25,550 --> 00:08:25,550
+الـY، الـY، الـY، الـY، الـY، الـY، الـY، الـY،
+
+111
+00:08:25,550 --> 00:08:25,570
+الـY، الـY، الـY، الـY، الـY، الـY، الـY، الـY،
+
+112
+00:08:25,570 --> 00:08:30,750
+الـY، الـY، الـY، الـY، الـY،
+
+113
+00:08:40,590 --> 00:08:46,270
+جليل exactly it's a small بظبط ولا لأ صح لأنه
+
+114
+00:08:46,270 --> 00:08:48,990
+effective وبتقل ال increasing the aggregate output
+
+115
+00:08:48,990 --> 00:08:54,290
+is larger than طب why is the change or does the
+
+116
+00:08:54,290 --> 00:08:57,130
+change in aggregate output is larger than the
+
+117
+00:08:57,130 --> 00:08:59,270
+change in the prices here okay
+
+118
+00:09:14,620 --> 00:09:20,180
+exactly but why my question is why in the short
+
+119
+00:09:20,180 --> 00:09:26,240
+run here why does the change in y is larger than
+
+120
+00:09:26,240 --> 00:09:31,010
+the change in the price levelExactly thank you
+
+121
+00:09:31,010 --> 00:09:35,130
+because the slope of aggregate supply curve in the
+
+122
+00:09:35,130 --> 00:09:39,990
+short run and the very short run is small or it
+
+123
+00:09:39,990 --> 00:09:43,930
+should be more elastic than the long run period or
+
+124
+00:09:43,930 --> 00:09:48,530
+stage صح exactly the elasticity that you have
+
+125
+00:09:48,530 --> 00:09:53,150
+studied in the micro economics تمام طيب let's go
+
+126
+00:09:59,560 --> 00:10:02,460
+على مجموعة الـ Aggregate curve أو مجموعة الـ
+
+127
+00:10:02,460 --> 00:10:09,060
+Aggregate supply curve، لا تعمل بشكل جيد على
+
+128
+00:10:09,060 --> 00:10:13,040
+المجموعة الـ Aggregate supply curve أو
+
+129
+00:10:13,040 --> 00:10:14,100
+مجموعة الـ Aggregate supply curve أو مجموعة الـ
+
+130
+00:10:14,100 --> 00:10:14,180
+Aggregate supply curve أو مجموعة الـ Aggregate
+
+131
+00:10:14,180 --> 00:10:16,200
+supply curve أو مجموعة الـ Aggregate supply curve
+
+132
+00:10:16,200 --> 00:10:17,120
+أو مجموعة الـ Aggregate supply curve أو مجموعة الـ
+
+133
+00:10:17,120 --> 00:10:17,380
+Aggregate supply curve أو مجموعة الـ Aggregate
+
+134
+00:10:17,380 --> 00:10:17,380
+supply curve أو مجموعة الـ Aggregate supply curve
+
+135
+00:10:17,380 --> 00:10:17,460
+أو مجموعة الـ Aggregate supply curve أو مجموعة الـ
+
+136
+00:10:17,460 --> 00:10:18,740
+Aggregate supply curve أو مجموعة الـ Aggregate
+
+137
+00:10:18,740 --> 00:10:21,200
+supply curve أو مجموعة الـ Aggregate supply curve
+
+138
+00:10:21,200 --> 00:10:23,180
+أو مجموعة الـ Aggregate supply curve أو مجموعة
+
+139
+00:10:24,860 --> 00:10:30,560
+مثلًا، إذا كنا نستخدم قيادة إتصالية، فهذا يسبب
+
+140
+00:10:30,560 --> 00:10:36,720
+فيها ارتفاع صغير في الـY وارتفاع كبير في الأسعار
+
+141
+00:10:36,720 --> 00:10:42,040
+لأن مستقبل مجموعة الـSupply Curve قريب من مجموعة
+
+142
+00:10:42,040 --> 00:10:46,840
+اتصالية مرتفعة. لكن في هذه الحالة، ماذا تقول؟ ماذا
+
+143
+00:10:46,840 --> 00:10:52,210
+عن إتصال المجموعة في الـPlanned Investment؟لدينا
+
+144
+00:10:52,210 --> 00:10:57,330
+مجموعات كبيرة أو مجموعات كبيرة في الاستثمار
+
+145
+00:10:57,330 --> 00:11:02,130
+المخطط، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم،
+
+146
+00:11:02,130 --> 00:11:02,250
+نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم،
+
+147
+00:11:02,250 --> 00:11:02,490
+نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم،
+
+148
+00:11:02,490 --> 00:11:02,490
+نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم،
+
+149
+00:11:02,490 --> 00:11:02,490
+نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم،
+
+150
+00:11:02,490 --> 00:11:02,490
+نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم، نعم،
+
+151
+00:11:02,490 --> 00:11:05,530
+نعم، نعم، نعم، نعم، نعم، نعم،
+
+152
+00:11:05,530 --> 00:11:05,650
+ن
+
+153
+00:11:09,110 --> 00:11:12,170
+سيكون حرارة المصادر المجاورة أقل أو أقل ، لذلك في
+
+154
+00:11:12,170 --> 00:11:15,710
+هذه الحالة إذا كنا نستخدم اتصال مصادر المصادر
+
+155
+00:11:15,710 --> 00:11:18,350
+المجاورة ، فهذا يؤدي إلى تحويل مصادر المصادر
+
+156
+00:11:18,350 --> 00:11:19,690
+المجاورة إلى حرارة المصادر المجاورة ، من حرارة
+
+157
+00:11:19,690 --> 00:11:21,510
+المصادر المجاورة لا إلى حرارة المصادر المجاورة إذا
+
+158
+00:11:21,510 --> 00:11:28,050
+كان لدينا نقطة إيقاف جديدة P لا P إلى P ، وهو يعني
+
+159
+00:11:29,390 --> 00:11:35,030
+أو نحن لدينا أكبر أزمة في الأسعار أو الانفلاك مع
+
+160
+00:11:35,030 --> 00:11:39,090
+ازمة صغيرة في الـ aggregate output لذلك في هذه
+
+161
+00:11:39,090 --> 00:11:47,730
+الحالة تقنية الانفلاك ماذا؟ مفيدة أو ليس مفيدة؟
+
+162
+00:11:47,730 --> 00:11:51,250
+لذلك لا سياسة المالية ولا النقدي فعالين في هذه
+
+163
+00:11:51,250 --> 00:11:57,610
+الحالة، مظبوط او لا؟ طيب، ماذا عن المرتبط؟ في هذه
+
+164
+00:11:57,610 --> 00:12:02,190
+الحالةفاكرين الـ Multiplier؟ اللي هو Delta Y
+
+165
+00:12:02,190 --> 00:12:05,870
+Multiplier الـ Government Spending Multiplier
+
+166
+00:12:05,870 --> 00:12:11,390
+Delta Y over Delta G الزيادة اللي صارت في ال
+
+167
+00:12:11,390 --> 00:12:16,830
+Government Spending زادت ال Y بالنسبة بسيطة جدا،
+
+168
+00:12:16,830 --> 00:12:19,750
+صح؟ مظبوط؟ يعني سببز أننا زدنا ال Government
+
+169
+00:12:19,750 --> 00:12:25,700
+Spending ال Y ممكن تزيد بحاجة بسيطة، smallبالنسبة
+
+170
+00:12:25,700 --> 00:12:29,780
+لهذا البرنامج قريب من أزرار أزرار في هذه الحالة
+
+171
+00:12:29,780 --> 00:12:33,120
+إذا كانت رحلة عضوية بالتأكيد البرنامج سيكون
+
+172
+00:12:33,120 --> 00:12:37,880
+أزرارًا أزرارًا صح؟ كله هذا الكلام أنه في مجموعة
+
+173
+00:12:37,880 --> 00:12:43,500
+عضوية الأسعار البرنامج لا يعمل جيدًا والبرنامج
+
+174
+00:12:43,500 --> 00:12:48,450
+قريبة من أزرار أزرارإذا كانت المستوى التجاري تكون
+
+175
+00:12:48,450 --> 00:12:52,850
+خطوة مرتفعة، في هذه الحالة، فإن أزمة الحكومة تتسبب
+
+176
+00:12:52,850 --> 00:12:53,910
+في أزمة التطبيقات التجارية تتسبب في أزمة التطبيقات
+
+177
+00:12:53,910 --> 00:12:55,350
+التجارية تتسبب في أزمة التطبيقات التجارية تتسبب في
+
+178
+00:12:55,350 --> 00:12:58,770
+أزمة التطبيقات التجارية تتسبب في أزمة التطبيقات
+
+179
+00:12:58,770 --> 00:13:01,230
+التجارية تتسبب في أزمة التطبيقات التجارية تتسبب في
+
+180
+00:13:01,230 --> 00:13:01,590
+أزمة التطبيقات التجارية تتسبب في أزمة التطبيقات
+
+181
+00:13:01,590 --> 00:13:02,550
+التجارية تتسبب في أزمة التطبيقات التجارية تتسبب في
+
+182
+00:13:02,550 --> 00:13:09,710
+أزمة التطبيقات التجارية تتسبب في أزمة
+
+183
+00:13:09,710 --> 00:13:15,040
+التطبيقات التجإذا كان الحكومة تستخدم حكومة عملية
+
+184
+00:13:15,040 --> 00:13:21,600
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+185
+00:13:21,600 --> 00:13:22,420
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+186
+00:13:22,420 --> 00:13:23,240
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+187
+00:13:23,240 --> 00:13:23,280
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+188
+00:13:23,280 --> 00:13:23,300
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+189
+00:13:23,300 --> 00:13:27,260
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+190
+00:13:27,260 --> 00:13:28,100
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+191
+00:13:28,100 --> 00:13:28,100
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+192
+00:13:28,100 --> 00:13:31,300
+عملية عملية عملية عملية
+
+193
+00:13:35,500 --> 00:13:41,540
+وهذا يعني أننا لدينا إزالة في الأسعار بدون تغيير
+
+194
+00:13:41,540 --> 00:13:50,400
+في الـ aggregate output لذلك لا يوجد تغيير في الـ
+
+195
+00:13:50,400 --> 00:13:54,960
+aggregate output لذلك يكون الـ Y موجودة في Y1
+
+196
+00:13:58,420 --> 00:14:03,360
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+197
+00:14:03,360 --> 00:14:05,340
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+198
+00:14:05,340 --> 00:14:05,660
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+199
+00:14:05,660 --> 00:14:07,480
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+200
+00:14:07,480 --> 00:14:09,440
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+201
+00:14:09,440 --> 00:14:09,580
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+202
+00:14:09,580 --> 00:14:09,580
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+203
+00:14:09,580 --> 00:14:09,580
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+204
+00:14:09,580 --> 00:14:09,580
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+205
+00:14:09,580 --> 00:14:10,340
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+206
+00:14:10,340 --> 00:14:17,900
+المزيد من المزيد من المزيد من المزيد من المزيد من
+
+207
+00:14:17,900 --> 00:14:24,320
+المزيد منصح؟ so in this case we have only
+
+208
+00:14:24,320 --> 00:14:27,940
+exchanges and or increasing the price levels or
+
+209
+00:14:27,940 --> 00:14:32,680
+inflation تمام؟ وهذه المنطقة بيسموها inflationary
+
+210
+00:14:32,680 --> 00:14:40,500
+gap فجوة تدخمية تمام؟ اه هذا جاي نعليها لغاية ان
+
+211
+00:14:40,500 --> 00:14:45,260
+شاء الله so when the economy works
+
+212
+00:14:47,710 --> 00:14:54,210
+أو تدفع في القوة هنا موضوع القوة الـ P' نحن لدينا
+
+213
+00:14:54,210 --> 00:14:59,510
+القوة أو القوة الكامة فإن إزالة أو استخدام اتفاق
+
+214
+00:14:59,510 --> 00:15:04,530
+فاسكال أو اتفاق مواليتور يتسبب في إزالة الأسعار
+
+215
+00:15:04,530 --> 00:15:11,650
+فقط بدون تغيير ولماذا؟ عندما نعمل قريتاthe
+
+216
+00:15:11,650 --> 00:15:14,770
+capacity يعني جريبين من ال capacity in this case
+
+217
+00:15:14,770 --> 00:15:17,570
+the expansion of fiscal policy leads to increasing
+
+218
+00:15:17,570 --> 00:15:21,270
+the prices with a smaller change in Y or a smaller
+
+219
+00:15:21,270 --> 00:15:25,330
+change in the aggregate output مين مش فاهم قايدله
+
+220
+00:15:25,330 --> 00:15:30,170
+في هذا الجزيه؟ واضحة؟ طب أحكي عربة ولا مصر؟ تمام
+
+221
+00:15:30,170 --> 00:15:32,490
+أنا أحكي English أحسن؟ okay
+
+222
+00:15:50,500 --> 00:15:57,000
+طيب so as you see if the aggregate supply curve is
+
+223
+00:15:57,000 --> 00:16:02,620
+a vertical in the long term إذا كان نعمل diagram
+
+224
+00:16:02,620 --> 00:16:07,580
+هيك if
+
+225
+00:16:07,580 --> 00:16:10,860
+the aggregate supply curve is a vertical line in
+
+226
+00:16:10,860 --> 00:16:13,480
+this case neither
+
+227
+00:16:15,000 --> 00:16:18,880
+الخاصية المراقبة أو الخاصية المراقبة لديها أي
+
+228
+00:16:18,880 --> 00:16:23,460
+افتتاح على الاختصار المراقبة مظبوط هاي في الوقت
+
+229
+00:16:23,460 --> 00:16:27,860
+طويل الخاصية
+
+230
+00:16:27,860 --> 00:16:33,600
+المراقبة هي اتجارة رقمية هنا المزيد أو استخدام
+
+231
+00:16:33,600 --> 00:16:37,120
+خاصية المراقبة أو الخاصية المراقبة المراقبة
+
+232
+00:16:37,120 --> 00:16:37,700
+المراقبة المراقبة المراقبة المراقبة المراقبة
+
+233
+00:16:37,700 --> 00:16:38,600
+المراقبة المراقبة المراقبة المراقبة المراقبة
+
+234
+00:16:38,600 --> 00:16:40,280
+المراقبة المراقبة المراقبة المراقبة المراقبة
+
+235
+00:16:40,280 --> 00:16:42,320
+المراقبة
+
+236
+00:16:44,090 --> 00:16:48,210
+وهذا يعني أننا لدينا زيادة في الأسعار بدون تغيير
+
+237
+00:16:48,210 --> 00:16:51,030
+في الواقع ولماذا؟ لذلك، لا يوجد أي تغيير في
+
+238
+00:16:51,030 --> 00:16:56,850
+الاستخدام أو تغيير في الاستخدام أو تغيير في
+
+239
+00:16:56,850 --> 00:16:58,070
+الاستخدام أو تغيير في الاستخدام أو تغير في
+
+240
+00:16:58,070 --> 00:16:59,450
+الاستخدام أو تغير في الاستخدام أو تغير في
+
+241
+00:16:59,450 --> 00:17:00,870
+الاستخدام أو تغير في الاستخدام أو تغير في
+
+242
+00:17:00,870 --> 00:17:02,830
+الاستخدام أو تغير في الاستخدام أو تغير في
+
+243
+00:17:02,830 --> 00:17:03,790
+الاستخدام أو تغير في الاستخدام أو تغير في
+
+244
+00:17:03,790 --> 00:17:03,790
+الاستخدام أو تغير في الاستخدام أو تغير في
+
+245
+00:17:03,790 --> 00:17:11,950
+الاستخدام أو تغير في الاستخدام أو
+
+246
+00:17:11,950 --> 00:17:21,440
+تغيروالـ crowding out أيضًا مظبوط لأن كل زيادات
+
+247
+00:17:21,440 --> 00:17:30,780
+اللي صارت في النتجة هيعمل backward مرة تانية دعونا
+
+248
+00:17:30,780 --> 00:17:37,800
+نذهب إلى هذا البرنامج باعتبار كينسيا البرنامج
+
+249
+00:17:37,800 --> 00:17:41,620
+باعتبار كينسيا البرنامج باعتبار كينسيا البرنامج
+
+250
+00:17:41,620 --> 00:17:45,150
+باعتبار كينسياflat or horizontal line and then
+
+251
+00:17:45,150 --> 00:17:48,950
+vertical line انا بتحكي عن very short run and long
+
+252
+00:17:48,950 --> 00:17:53,690
+run تمام خليني اعمل الرسم هنا وبعدين نعمل ال
+
+253
+00:17:53,690 --> 00:17:57,810
+analysis okay so
+
+254
+00:17:57,810 --> 00:18:02,650
+according to the keynesian view let's analyze the
+
+255
+00:18:02,650 --> 00:18:06,950
+policy effects or the policies effects or the
+
+256
+00:18:06,950 --> 00:18:09,810
+aggregate output according to the keynesian view
+
+257
+00:18:11,390 --> 00:18:19,390
+لدينا اتصالات او اتصالات او اتصالات او
+
+258
+00:18:19,390 --> 00:18:19,510
+اتصالات او اتصالات او اتصالات او اتصالات اتصالات
+
+259
+00:18:19,510 --> 00:18:23,870
+اتصالات اتصالات
+
+260
+00:18:23,870 --> 00:18:25,750
+اتصالات اتصالات اتصالات اتصالات اتصالات اتصالات
+
+261
+00:18:25,750 --> 00:18:26,910
+اتصالات اتصالات اتصالات اتصالات اتصالات اتصالات
+
+262
+00:18:26,910 --> 00:18:26,990
+اتصالات اتصالات اتصالات اتصالات اتصالات اتصالات
+
+263
+00:18:26,990 --> 00:18:28,090
+اتصالات اتصالات اتصالات اتصالات اتصالات اتصالات
+
+264
+00:18:28,090 --> 00:18:31,790
+اتصالات اتصالات اتصالات اتصالات اتصالات اتصالات
+
+265
+00:18:31,790 --> 00:18:36,070
+اتصالات اتصال
+
+266
+00:18:37,070 --> 00:18:46,130
+اعتبار الـ E1 او الـ E هنا سنقوم بالتحليق هذا هو
+
+267
+00:18:46,130 --> 00:18:55,150
+السبب في مجموعة الاسعار 1 C plus I plus G plus X
+
+268
+00:18:55,150 --> 00:19:03,030
+minus M اعتبار هذا الـ E1
+
+269
+00:19:04,380 --> 00:19:12,020
+وهذا هو اتجارة اتجارة Y اتجارة
+
+270
+00:19:12,020 --> 00:19:24,380
+Y اتجارة Y اتجارة Y اتجارة Y اتجارة Y اتجارة Y
+
+271
+00:19:24,380 --> 00:19:33,170
+اتجارة Y اتجارة Yالإيقاليبريام هنا يحدث عندما
+
+272
+00:19:33,170 --> 00:19:36,170
+تتجاوز المصادر المجاورة إلى طلب المجاور المجاور
+
+273
+00:19:36,170 --> 00:19:37,610
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+274
+00:19:37,610 --> 00:19:39,390
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+275
+00:19:39,390 --> 00:19:39,450
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+276
+00:19:39,450 --> 00:19:41,710
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+277
+00:19:41,710 --> 00:19:42,850
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+278
+00:19:42,850 --> 00:19:46,470
+المجاور المجاور
+
+279
+00:19:46,470 --> 00:19:48,370
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+280
+00:19:48,370 --> 00:19:53,250
+المجاور المجاور المجاور المجاور المجاور المجاور
+
+281
+00:19:53,250 --> 00:19:59,370
+المجاور
+
+282
+00:19:59,370 --> 00:20:07,210
+المجاصح؟ So here we have what؟ Upward shifting of
+
+283
+00:20:07,210 --> 00:20:10,390
+the aggregate expenditure function and increasing
+
+284
+00:20:10,390 --> 00:20:12,970
+the aggregate demand. So suppose this is aggregate
+
+285
+00:20:12,970 --> 00:20:17,530
+demand 2. Here we have E2. What do you see? This
+
+286
+00:20:17,530 --> 00:20:25,810
+is P1 and P2 Y1 This
+
+287
+00:20:25,810 --> 00:20:27,730
+is Y1
+
+288
+00:20:29,470 --> 00:20:41,190
+Y2 صح او YF سببز ان YF هى Y Okay Y2 So the using
+
+289
+00:20:41,190 --> 00:20:44,010
+of an expansion fiscal policy leads to increasing
+
+290
+00:20:44,010 --> 00:20:47,290
+aggregate demand from a or a rightward shifting of
+
+291
+00:20:47,290 --> 00:20:49,350
+the aggregate demand from aggregate demand one to
+
+292
+00:20:49,350 --> 00:20:51,330
+aggregate demand two at the same time the
+
+293
+00:20:51,330 --> 00:20:54,510
+aggregate expenditure function increased and shift
+
+294
+00:20:54,510 --> 00:20:57,990
+to the upward there is upward shifting and the
+
+295
+00:20:57,990 --> 00:21:04,530
+aggregateexpenditure 2 this is aggregate
+
+296
+00:21:04,530 --> 00:21:10,930
+expenditure 2 sorry Y شو لسه aggregate expenditure
+
+297
+00:21:10,930 --> 00:21:17,370
+وين راح upward shifting بقى جاي بشكل parallel to
+
+298
+00:21:17,370 --> 00:21:20,250
+the previous case this is aggregate expenditure 2
+
+299
+00:21:20,250 --> 00:21:26,030
+this is E2 right تمام هذا شو يعمل في ال Y this is
+
+300
+00:21:26,030 --> 00:21:27,650
+Y1
+
+301
+00:21:30,900 --> 00:21:38,340
+Y2 مظبوط هنا شو لسه ال prices ماتغيرتش remains
+
+302
+00:21:38,340 --> 00:21:46,240
+constant P1 P2 P1 equals P2 صح طيب now the
+
+303
+00:21:46,240 --> 00:21:52,770
+capacity reached at point E2 here مظبوطهذا ال
+
+304
+00:21:52,770 --> 00:21:56,490
+capacity our full capacity utilization سببه ان ال
+
+305
+00:21:56,490 --> 00:21:59,730
+government راحت شو عامله increasing its spending
+
+306
+00:21:59,730 --> 00:22:03,910
+once again راحوا عاملين زيادة في ال aggregate
+
+307
+00:22:03,910 --> 00:22:10,150
+demand او ال government spending once againleads
+
+308
+00:22:10,150 --> 00:22:12,550
+to increasing aggregate expenditure and increase
+
+309
+00:22:12,550 --> 00:22:16,050
+aggregate demand but what shall .. what do you see
+
+310
+00:22:16,050 --> 00:22:18,590
+for the aggregate output؟ هلأ شو اللي بيصير؟ ال
+
+311
+00:22:18,590 --> 00:22:21,850
+aggregate demand will shift to the right once
+
+312
+00:22:21,850 --> 00:22:30,010
+again A D 3 تمام؟ شو اللي صار؟ this is A3 the
+
+313
+00:22:30,010 --> 00:22:34,310
+price is increased from B2 to B3 without a change
+
+314
+00:22:34,310 --> 00:22:37,790
+in Y in the long term this is Y3 طب نيجي للرسم
+
+315
+00:22:37,790 --> 00:22:41,380
+التاني يشوف شو اللي صار فيها؟الـ Increasing اللي
+
+316
+00:22:41,380 --> 00:22:43,420
+صار في ال aggregate demand او aggregate
+
+317
+00:22:43,420 --> 00:22:46,480
+expenditure هو عمل upward shifting للـ function
+
+318
+00:22:46,480 --> 00:22:56,840
+صح؟ إذا صار في عندى نعمله باللون الأزرق هيك this
+
+319
+00:22:56,840 --> 00:23:01,760
+is aggregate expenditure 3 وين جينا؟ Y increased
+
+320
+00:23:01,760 --> 00:23:13,050
+to Y3 مظبوط؟ صح؟طيب هاد المنطقة this is E3صار في
+
+321
+00:23:13,050 --> 00:23:16,050
+عندى increasing او upward shifting في الـ
+
+322
+00:23:16,050 --> 00:23:18,930
+aggregate expenditure من aggregate expenditure 2 ل
+
+323
+00:23:18,930 --> 00:23:23,770
+aggregate expenditure 3 صح؟ بس قولنا انه في عندى
+
+324
+00:23:23,770 --> 00:23:27,130
+fully crowding out بعد الـ full capacity
+
+325
+00:23:27,130 --> 00:23:31,810
+utilization هذا بعد النقطة هيك بعد a2 صحيح صار في
+
+326
+00:23:31,810 --> 00:23:33,730
+عندى ال increasing اللى صار في aggregate
+
+327
+00:23:33,730 --> 00:23:38,070
+expenditure زود النتج بس النتج هيرجع يرجع ل y2
+
+328
+00:23:38,070 --> 00:23:44,960
+لأنه في عندى fully crowding outمظبوط؟ و هذا اسمه
+
+329
+00:23:44,960 --> 00:23:48,600
+إذا هيرجع مرة تانية ينزل ال aggregate expenditure
+
+330
+00:23:48,600 --> 00:23:51,380
+من aggregate expenditure تلاتة ل aggregate
+
+331
+00:23:51,380 --> 00:23:55,940
+expenditure اتنين due to the crowding out effect
+
+332
+00:23:55,940 --> 00:23:58,900
+اللي هو ال fully crowding out إذا ال fully
+
+333
+00:23:58,900 --> 00:24:02,460
+crowding out وين رجعني؟ رجعني from aggregate
+
+334
+00:24:02,460 --> 00:24:04,940
+expenditure تلاتة ل aggregate expenditure اتنين
+
+335
+00:24:04,940 --> 00:24:10,860
+إذا وين ال potential GDP في هذا الحلم؟Y2 exactly
+
+336
+00:24:10,860 --> 00:24:15,820
+thank you Y2 صحيح أنا رجعت روحت زدت ل Y3 here but
+
+337
+00:24:15,820 --> 00:24:21,880
+the finally I came back to Y2 هذه المنطقة between
+
+338
+00:24:21,880 --> 00:24:29,420
+E2 to E3 هذه بيسموها ال inflationary gap صح هذه
+
+339
+00:24:29,420 --> 00:24:34,280
+المنطقة هيك او من هنا E2 to E3 is the inflationary
+
+340
+00:24:34,280 --> 00:24:39,510
+gap لأن ال prices طلعت without a change in Yمظبوط؟
+
+341
+00:24:39,510 --> 00:24:47,470
+هل عدم زيادة في ال y نتيجتها إيش؟ أو بسبب شو؟ what
+
+342
+00:24:47,470 --> 00:24:56,510
+are the main causes of .. تمام and .. the
+
+343
+00:24:56,510 --> 00:24:59,330
+multiplier is zero exactly and we have a full
+
+344
+00:24:59,330 --> 00:25:04,660
+crowding outمن مش فاهم اعيدله الشباب اذا لو رجعنا
+
+345
+00:25:04,660 --> 00:25:07,740
+if we come back here this is the original
+
+346
+00:25:07,740 --> 00:25:11,320
+equilibrium point aggregate demand one intersects
+
+347
+00:25:11,320 --> 00:25:16,940
+aggregate supply and here we have a one this is a
+
+348
+00:25:16,940 --> 00:25:24,740
+one and the aggregate output is y one تمامتأثير
+
+349
+00:25:24,740 --> 00:25:30,380
+اقتصادي يؤدي إلى زيادة او تحويل مصطلح الواحد إلى
+
+350
+00:25:30,380 --> 00:25:34,060
+مصطلح المصطلح الثاني مصطلح المصطلح الثاني مصطلح
+
+351
+00:25:34,060 --> 00:25:36,800
+الواحد إلى مصطلح المصطلح الثاني مصطلح الواحد إلى
+
+352
+00:25:36,800 --> 00:25:37,480
+مصطلح المصطلح الثاني مصطلح الواحد إلى مصطلح
+
+353
+00:25:37,480 --> 00:25:38,880
+المصطلح الثاني مصطلح الواحد إلى مصطلح المصطلح
+
+354
+00:25:38,880 --> 00:25:40,540
+الثاني مصطلح الواحد إلى مصطلح المصطلح الثاني مصطلح
+
+355
+00:25:40,540 --> 00:25:42,940
+الواحد إلى مصطلح المصطلح الثاني مصطلح الواحد إلى
+
+356
+00:25:42,940 --> 00:25:51,260
+مصطلح المصطلح الثاني مصط
+
+357
+00:25:53,270 --> 00:25:57,330
+أضافة تجارب تجارب تجارب التحقيق أو تجارب التحقيق
+
+358
+00:25:57,330 --> 00:26:03,650
+أو تجارب التحقيق تجارب تجارب
+
+359
+00:26:03,650 --> 00:26:04,730
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+360
+00:26:04,730 --> 00:26:05,310
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+361
+00:26:05,310 --> 00:26:05,850
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+362
+00:26:05,850 --> 00:26:05,850
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+363
+00:26:05,850 --> 00:26:05,850
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+364
+00:26:05,850 --> 00:26:09,470
+تجارب تجارب تجارب تجارب تج
+
+365
+00:26:12,150 --> 00:26:15,910
+ولكن الانتجار الواضح عندما يتحرك المصادر
+
+366
+00:26:15,910 --> 00:26:24,410
+الانتجارية لـ 2 إلى 3 يعني أو يقوم بإزالة أسعار من
+
+367
+00:26:24,410 --> 00:26:25,490
+P1 إلى P3
+
+368
+00:26:28,350 --> 00:26:31,370
+There is a upward shifting or increasing in the
+
+369
+00:26:31,370 --> 00:26:36,890
+prices without changing Y So Y would decline to YF
+
+370
+00:26:36,890 --> 00:26:42,090
+So YF is what؟ The potential GDP in the long term
+
+371
+00:26:42,090 --> 00:26:46,150
+هذا أقصى حد ممكن يوصل إلى النتجة حتى و لو زاد
+
+372
+00:26:46,150 --> 00:26:51,610
+هيرجع مرة تانية تمام؟
+
+373
+00:26:51,610 --> 00:26:56,430
+هذه المنطقة هيك is inflationary gap لأنه في مجرد
+
+374
+00:26:56,430 --> 00:26:57,370
+زيادات في الأسعار
+
+375
+00:27:00,310 --> 00:27:05,470
+إذا تتذكر في الحلقة الأولى، نحن نتكلم عن مصطلح
+
+376
+00:27:05,470 --> 00:27:11,030
+الانفلاش، وهو ماذا؟ إزالة قيمة الأسعار العامة
+
+377
+00:27:11,030 --> 00:27:14,290
+والإنفلاش
+
+378
+00:27:14,290 --> 00:27:18,410
+المستمرة، كما يحدث عندما تزال قيمة الأسعار العامة
+
+379
+00:27:18,410 --> 00:27:27,880
+ترتفع على بعضها في الوقت طويل،لدينا اثنين نوعين من
+
+380
+00:27:27,880 --> 00:27:32,870
+الاستخدامit's called the demand pull inflation
+
+381
+00:27:32,870 --> 00:27:36,470
+التضخم اللي جاء نتيجة الطلب الطلب بزيد وبتالي
+
+382
+00:27:36,470 --> 00:27:42,730
+عمليا ال prices بتطلع صح؟ شباب we have two types
+
+383
+00:27:42,730 --> 00:27:45,970
+of inflation number one it's called demand pull
+
+384
+00:27:45,970 --> 00:27:49,670
+inflation and the second is cost push inflation or
+
+385
+00:27:49,670 --> 00:27:53,210
+supply side inflation ال demand pull inflation
+
+386
+00:27:53,210 --> 00:27:56,670
+means increasing the aggregate demand which leads
+
+387
+00:27:56,670 --> 00:28:00,920
+to increasing the pricesيعني شو اللي خلّى انه ال
+
+388
+00:28:00,920 --> 00:28:03,820
+aggregate demand يزيد او شو اللي خلّى ال prices
+
+389
+00:28:03,820 --> 00:28:06,700
+تزيد ال inflation يزيد ال aggregate demand
+
+390
+00:28:06,700 --> 00:28:10,460
+increase maybe by using as a result or due to the
+
+391
+00:28:10,460 --> 00:28:12,840
+expansion policy or expansion fiscal or
+
+392
+00:28:12,840 --> 00:28:16,600
+expansionary monetary policy right؟ what about the
+
+393
+00:28:16,600 --> 00:28:22,040
+cost push inflation؟ شو سبب انه ال prices طلع؟
+
+394
+00:28:22,040 --> 00:28:26,990
+increasing the cost of productionمصبوط؟ لـ
+
+395
+00:28:26,990 --> 00:28:29,210
+increasing the cost of production like increasing
+
+396
+00:28:29,210 --> 00:28:32,290
+the prices of inputs to increase the wages leads
+
+397
+00:28:32,290 --> 00:28:36,150
+to what? leads to decrease the .. exactly the
+
+398
+00:28:36,150 --> 00:28:39,590
+prices would increase تمام؟ so we have a leftward
+
+399
+00:28:39,590 --> 00:28:42,690
+shifting in the aggregate supply curve which means
+
+400
+00:28:42,690 --> 00:28:46,490
+increasing the prices from .. we have a .. a new
+
+401
+00:28:46,490 --> 00:28:48,990
+equilibrium point from A1 to A2 which means
+
+402
+00:28:48,990 --> 00:28:53,270
+increasing the prices from A note .. P note to P1
+
+403
+00:28:53,520 --> 00:28:55,980
+لذالك لدينا اتفاقين اتفاقين اتفاقين اتفاقين
+
+404
+00:28:55,980 --> 00:29:01,420
+اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين
+
+405
+00:29:01,420 --> 00:29:05,840
+اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين
+
+406
+00:29:05,840 --> 00:29:06,160
+اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين
+
+407
+00:29:06,160 --> 00:29:06,220
+اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين
+
+408
+00:29:06,220 --> 00:29:11,540
+اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين اتفاقين
+
+409
+00:29:11,540 --> 00:29:18,860
+اتفاقين اتفاقين ا
+
+410
+00:29:21,210 --> 00:29:27,230
+بالضبط لدينا إزالة الأسعار أو الإنفلاش وإزالة
+
+411
+00:29:27,230 --> 00:29:36,190
+عمليات العمليات في نفس الوقت كما
+
+412
+00:29:36,190 --> 00:29:40,870
+ذكرنا قبل عندما
+
+413
+00:29:40,870 --> 00:29:44,630
+كان الحكومة
+
+414
+00:29:44,630 --> 00:29:49,530
+تستخدم حكومة عمليات العمليات هذا يدفع إلى إزالة
+
+415
+00:29:49,530 --> 00:29:55,170
+عمليات العملياتلنقوم بعمل تجارب تجارب تجارب تجارب
+
+416
+00:29:55,170 --> 00:30:02,130
+تجارب تجارب
+
+417
+00:30:02,130 --> 00:30:04,870
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+418
+00:30:04,870 --> 00:30:05,130
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+419
+00:30:05,130 --> 00:30:05,130
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+420
+00:30:05,130 --> 00:30:05,130
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+421
+00:30:05,130 --> 00:30:05,210
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+422
+00:30:05,210 --> 00:30:20,510
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب ت
+
+423
+00:30:21,520 --> 00:30:32,360
+aggregate demand one one a one p one y one this is
+
+424
+00:30:32,360 --> 00:30:34,760
+prices y
+
+425
+00:30:36,520 --> 00:30:40,680
+هذه هي الوصولة الآن فاعتبار أن الحكومة استخدمت
+
+426
+00:30:40,680 --> 00:30:45,520
+تنفيذ تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+427
+00:30:45,520 --> 00:30:45,680
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+428
+00:30:45,680 --> 00:30:45,820
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+429
+00:30:45,820 --> 00:30:46,500
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+430
+00:30:46,500 --> 00:30:46,940
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+431
+00:30:46,940 --> 00:30:47,420
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+432
+00:30:47,420 --> 00:30:47,500
+تجارب تجارب
+
+433
+00:31:05,470 --> 00:31:15,770
+هذا هو اي اتو عندما تزال السعر يزال يزال يزال يزال
+
+434
+00:31:15,770 --> 00:31:17,150
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزل
+
+435
+00:31:17,150 --> 00:31:21,490
+يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل
+
+436
+00:31:21,490 --> 00:31:21,890
+يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل
+
+437
+00:31:21,890 --> 00:31:21,890
+يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل
+
+438
+00:31:21,890 --> 00:31:21,890
+يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل
+
+439
+00:31:21,890 --> 00:31:25,370
+يزل يزل يزل يزل يزل يزل يزل يDecrease Aggregate
+
+440
+00:31:25,370 --> 00:31:31,390
+Supply لذلك هناك اتفاق اتفاق اتفاق اتفاق اتفاق
+
+441
+00:31:31,390 --> 00:31:38,690
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+442
+00:31:38,690 --> 00:31:40,530
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+443
+00:31:40,530 --> 00:31:41,450
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+444
+00:31:41,450 --> 00:31:41,450
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+445
+00:31:41,450 --> 00:31:41,530
+اتفاق اتفاق اتفاق اتفاق اتفاق
+
+446
+00:31:55,820 --> 00:31:59,260
+هل ال increasing في ال prices from P1 to P2 to P3
+
+447
+00:31:59,260 --> 00:32:03,940
+شو اسمه هذا؟ Inflation طيب ال decreasing اللي صار
+
+448
+00:32:03,940 --> 00:32:07,940
+في ال aggregate output هذا تخفيض النترية شو معناه؟
+
+449
+00:32:07,940 --> 00:32:13,120
+ان البطالي زادت exactly exactly إذا هذا ال
+
+450
+00:32:13,120 --> 00:32:19,640
+increasing في ال prices from P1 to P3 شو معناه؟
+
+451
+00:32:19,640 --> 00:32:25,040
+Inflation at the same time yes
+
+452
+00:32:27,650 --> 00:32:31,150
+الزيارة طبعا ال Y، بس لما لاحظت ال 3 طب بلجأ ال Y،
+
+453
+00:32:31,150 --> 00:32:34,510
+كيف صارت هذا؟ ال rejoin اللي صار في ال Y هذا، شو
+
+454
+00:32:34,510 --> 00:32:37,890
+معناه from Y2 to Y3؟ إن ال cost of production طلع
+
+455
+00:32:38,750 --> 00:32:42,290
+صار في عندك cost push inflation او supply side
+
+456
+00:32:42,290 --> 00:32:45,790
+inflation شو اللي صار الارتفاع اللي صار في الأسعار
+
+457
+00:32:45,790 --> 00:32:49,830
+شو عمل increased في ال wages مظبوط زيادة في ال
+
+458
+00:32:49,830 --> 00:32:52,230
+wages شو عملت في ال cost of production زودت ال
+
+459
+00:32:52,230 --> 00:32:56,070
+cost of production وبالتالي ال ability تبع ال
+
+460
+00:32:56,070 --> 00:32:59,090
+producers انه ينتجوا more and more would decline
+
+461
+00:32:59,090 --> 00:33:02,210
+وبالتالي aggregate supply would decline so there
+
+462
+00:33:02,210 --> 00:33:05,470
+is a backward shifting او a leftward shifting في
+
+463
+00:33:05,470 --> 00:33:07,210
+ال aggregate supply curve from aggregate supply
+
+464
+00:33:07,210 --> 00:33:12,250
+one to aggregate supply twoطيب شو عمل هذا؟ this is
+
+465
+00:33:12,250 --> 00:33:15,750
+a3 شو اللي عمل؟ عملنا backward shifting في ال
+
+466
+00:33:15,750 --> 00:33:20,630
+aggregate supply، ال prices طلعت و ال Y نزل، هلأ
+
+467
+00:33:20,630 --> 00:33:23,890
+ال increasing في ال prices شو معناه؟ what is the
+
+468
+00:33:23,890 --> 00:33:27,150
+meaning of increasing the prices؟ inflation، plus
+
+469
+00:33:27,150 --> 00:33:31,790
+ال decreasing اللي صار في ال Y from Y2 to Y3
+
+470
+00:33:34,370 --> 00:33:36,630
+النتج لما بنزل، شو بيصير في ال unemployment؟
+
+471
+00:33:36,630 --> 00:33:38,710
+معناه، this means ان ال unemployment rate
+
+472
+00:33:38,710 --> 00:33:42,970
+increased، so this means ان we have increasing in
+
+473
+00:33:42,970 --> 00:33:48,750
+the unemployment rate which is a stagnation،
+
+474
+00:33:48,750 --> 00:33:52,690
+واضحة؟ اذا ال stagnation means increasing in the
+
+475
+00:33:52,690 --> 00:33:55,010
+price .. in the overall price levels and
+
+476
+00:33:55,010 --> 00:34:00,070
+increasing and .. for the unemployment at the same
+
+477
+00:34:00,070 --> 00:34:07,620
+time، تمام؟مين اعيدله مش وانا فاهم اوضحله اشي تمام
+
+478
+00:34:07,620 --> 00:34:17,500
+okay yes yes the potential is no y3 ال potential
+
+479
+00:34:17,500 --> 00:34:22,340
+GDP is y3 هذا potential with inflation potential
+
+480
+00:34:22,340 --> 00:34:28,900
+without inflation y1صح؟ بظبط لأنه الناتج هنا
+
+481
+00:34:28,900 --> 00:34:32,880
+increased and then declined and this is in the
+
+482
+00:34:32,880 --> 00:34:48,800
+long term طيب
+
+483
+00:34:48,800 --> 00:34:52,760
+اوك كده change الله تعالى .. okay
+
+484
+00:35:02,320 --> 00:35:09,480
+Expectation and inflation شو
+
+485
+00:35:09,480 --> 00:35:12,880
+الإلاقة ما بين ال expectation about the future أو
+
+486
+00:35:12,880 --> 00:35:16,600
+expectation about something and inflation ال
+
+487
+00:35:16,600 --> 00:35:21,740
+expectations about the changes and future prices
+
+488
+00:35:21,740 --> 00:35:26,120
+may affect current decisions إذا أنا بتوقع أن
+
+489
+00:35:26,120 --> 00:35:28,620
+الأسعار هترتفع خلال الفترة الجاية شو اللي بيعمل؟
+
+490
+00:35:28,620 --> 00:35:32,860
+شو اللي بيصير عنداه؟الـ firms may raise their
+
+491
+00:35:32,860 --> 00:35:36,320
+prices in expectation of competitors doing and the
+
+492
+00:35:36,320 --> 00:35:39,520
+competitors will do the same، إذا مؤسسة بتتوقع
+
+493
+00:35:39,520 --> 00:35:43,020
+أنها الأسعار بتطلع و حدا راح رفع الأسعار، الكل
+
+494
+00:35:43,020 --> 00:35:45,520
+برفع الأسعار، هذا واحد، مظبوط؟
+
+495
+00:35:53,900 --> 00:36:00,160
+العمال اللي بتوقعه
+
+496
+00:36:00,160 --> 00:36:04,740
+العمال اللي بتوقعه ان ال prices هتطلع يروح يطلبوا
+
+497
+00:36:04,740 --> 00:36:05,620
+أجور أعلى
+
+498
+00:36:15,520 --> 00:36:18,860
+مش هو الـ hyperinflation؟ الـ rapid increase in
+
+499
+00:36:18,860 --> 00:36:22,060
+the overall price levels in the long term، بصبح؟
+
+500
+00:36:22,060 --> 00:36:27,580
+quickly، ال prices بتطلع بسرعة، so here as you see
+
+501
+00:36:27,580 --> 00:36:31,480
+the equilibrium occurs when aggregate demand does
+
+502
+00:36:31,480 --> 00:36:34,880
+not intersect the aggregate supply، سببوز إنه في
+
+503
+00:36:34,880 --> 00:36:40,900
+عندنا expenditure fiscal policy، the increasing in
+
+504
+00:36:40,900 --> 00:36:50,740
+government spendingwith or without a change and
+
+505
+00:36:50,740 --> 00:36:55,760
+monitor policy شوف
+
+506
+00:36:55,760 --> 00:37:00,460
+تعمل increase aggregate demand so there is a right
+
+507
+00:37:00,460 --> 00:37:04,840
+word shifting and aggregate demand curve تمام شوف
+
+508
+00:37:04,840 --> 00:37:07,520
+سيف ال prices would increase اعمل كمان مرة
+
+509
+00:37:07,520 --> 00:37:10,460
+increasing في ال aggregate demand to aggregate
+
+510
+00:37:10,460 --> 00:37:14,460
+demand two increasing aggregate demand three so
+
+511
+00:37:15,890 --> 00:37:21,590
+لدينا إزالة عالية في مقاومة الأسعار العامة بسبب
+
+512
+00:37:21,590 --> 00:37:24,750
+إزالة
+
+513
+00:37:24,750 --> 00:37:27,450
+مقاومة الأسعار العامة بسبب إزالة مقاومة الأسعار
+
+514
+00:37:27,450 --> 00:37:28,370
+العامة بسبب إزالة مقاومة الأسعار العامة بسبب إزالة
+
+515
+00:37:28,370 --> 00:37:32,810
+مقاومة الأسعار العامة بسبب إزالة مقاومة الأسعار
+
+516
+00:37:32,810 --> 00:37:36,230
+العامة بسبب إزالة مقاومة الأسعار العامة بسبب إزالة
+
+517
+00:37:36,230 --> 00:37:38,630
+مقاومة الأسعار العامة بسبب إزالة مقاومة الأسعار
+
+518
+00:37:38,630 --> 00:37:39,370
+العامة بسبب إزالة مقاومة الأسعار العامة بسبب إزالة
+
+519
+00:37:39,370 --> 00:37:44,970
+مقاومة الأسعار العامة بسبب إزالة
+
+520
+00:37:44,970 --> 00:37:47,800
+مقاومالـ Increasing in the governance funding شو
+
+521
+00:37:47,800 --> 00:37:51,640
+عمل؟ Without a change في الـ Monetary Policy شو
+
+522
+00:37:51,640 --> 00:37:53,880
+عمل؟ Increased aggregate demand أو aggregate
+
+523
+00:37:53,880 --> 00:37:57,560
+expenditure مظبوط Which leads to increasing Y
+
+524
+00:37:57,560 --> 00:38:03,000
+Increased money demand Increased
+
+525
+00:38:03,000 --> 00:38:07,500
+R إذن هذا شو عمل؟ Increasing في الـR واللي عمل
+
+526
+00:38:07,500 --> 00:38:10,580
+Decreasing في الـI وهذا اسمه The crowding out So
+
+527
+00:38:10,580 --> 00:38:14,290
+the crowding out would increaseبصبوح هذا ال
+
+528
+00:38:14,290 --> 00:38:25,450
+analysis تبع ال diagram هذا نفس
+
+529
+00:38:25,450 --> 00:38:31,200
+ال the sameوالـ slide بيقول إنه an increase in the
+
+530
+00:38:31,200 --> 00:38:34,600
+government spending with money supply constants
+
+531
+00:38:34,600 --> 00:38:36,920
+will shift the aggregate demand curve from
+
+532
+00:38:36,920 --> 00:38:40,160
+aggregate demand one to aggregate demand two and
+
+533
+00:38:40,160 --> 00:38:44,440
+so on although not shown in the figure this leads
+
+534
+00:38:44,440 --> 00:38:47,300
+to an increase in the interest rate ده اللي حللناه
+
+535
+00:38:47,300 --> 00:38:50,060
+وبالتالي ال crowding out would increase ال
+
+536
+00:38:50,060 --> 00:38:52,140
+crowding out in the planned investment would
+
+537
+00:38:52,140 --> 00:38:57,140
+increaseطب خليني أشوف أنه suppose there is a
+
+538
+00:38:57,140 --> 00:39:00,120
+change in the money supply or the monetary policy
+
+539
+00:39:00,120 --> 00:39:07,740
+what would happen؟
+
+540
+00:39:09,940 --> 00:39:13,940
+هلأ without a change شو عمل؟ عملنا hyperinflation
+
+541
+00:39:13,940 --> 00:39:18,360
+if the money supply remains constant without a
+
+542
+00:39:18,360 --> 00:39:21,420
+change يعني ماغيروش .. يأثروا على سعر الفائدة
+
+543
+00:39:21,420 --> 00:39:24,880
+suppose we use an exponential fiscal policy، تمام،
+
+544
+00:39:24,880 --> 00:39:28,320
+هذا شو عمل؟ رفع ال interest rate، صح؟ وخلق مشكلة
+
+545
+00:39:28,320 --> 00:39:32,400
+crowding out، أظبط ولا لأ؟ هلأ ال prices شو بيصير
+
+546
+00:39:32,400 --> 00:39:36,950
+فيها؟ كل ما بيزيدالـ .. الـ government spending ال
+
+547
+00:39:36,950 --> 00:39:39,830
+aggregate demand would increase which means we
+
+548
+00:39:39,830 --> 00:39:42,970
+have a rapid increasing in the price levels،
+
+549
+00:39:42,970 --> 00:39:46,970
+مظبوط؟ هذا without intervention by the central
+
+550
+00:39:46,970 --> 00:39:49,850
+bank to increase the money supply، اللي بنتش نلغي
+
+551
+00:39:49,850 --> 00:39:55,230
+without اللي هو الغاء .. بدون الغاء أثر ال
+
+552
+00:39:55,230 --> 00:39:58,780
+interest rate على ال investmentطب خلينا نشوف لو
+
+553
+00:39:58,780 --> 00:40:01,940
+راحوا عاملين راحوا ال central bank مزود ال money
+
+554
+00:40:01,940 --> 00:40:05,040
+supply يعني صارت في عنده increasing هنا في ال
+
+555
+00:40:05,040 --> 00:40:08,000
+aggregate demand from aggregate demand no to
+
+556
+00:40:08,000 --> 00:40:11,160
+aggregate demand one to two to three خلينا without
+
+557
+00:40:11,160 --> 00:40:14,320
+it change ال money supply بس خلينا نشوف انهم راحوا
+
+558
+00:40:14,320 --> 00:40:18,240
+بدهم يلغوا تأثير ال Rأحنا مشكلتنا في الـ crowding
+
+559
+00:40:18,240 --> 00:40:22,500
+out وين؟ إنه الـ interest rate طلع وبتتمنى نزل الـ
+
+560
+00:40:22,500 --> 00:40:24,720
+aggregate لـ planned investment وبتنهي نزل ال Y،
+
+561
+00:40:24,720 --> 00:40:29,020
+صح؟ هلقيت؟ خلّيني نشوف إنه عشان يلغوا تأثير الـ R،
+
+562
+00:40:29,020 --> 00:40:33,300
+شغلنا بنعمل في الـ monosupply؟ نحتاج لإزالة الـ
+
+563
+00:40:33,300 --> 00:40:36,380
+monosupply، فلأ إذا بتذكروا، إذا بتذكروا، عشان
+
+564
+00:40:36,380 --> 00:40:40,200
+نلغوا موضوع الـ crowding out، لازم نعمل شو؟ نزود
+
+565
+00:40:40,200 --> 00:40:43,600
+الـ monosupply، لأن الإشكال يوين كانت عندنا، خليني
+
+566
+00:40:43,600 --> 00:40:46,360
+أرجحكم شوية لموضوع الـ monosupply و الـ monodemand
+
+567
+00:40:50,060 --> 00:40:55,280
+this is the money supply one money demand one هذا
+
+568
+00:40:55,280 --> 00:40:58,040
+بدأ أرجعكم شويه عشان قبل ما أفوت على النقطة هاي
+
+569
+00:40:58,040 --> 00:41:07,540
+this is E one R one AQM one تمام هلأ في الحالة هذه
+
+570
+00:41:07,540 --> 00:41:10,160
+increasing the government spending شو عملني؟ عملنا
+
+571
+00:41:10,160 --> 00:41:12,560
+increasing في ال money demand وبالتالي there is a
+
+572
+00:41:12,560 --> 00:41:15,820
+rightward shifting in the money demand curve صح؟
+
+573
+00:41:15,820 --> 00:41:21,280
+شو يعمل فيه؟تقوم ديتو رافع ال interest rate from
+
+574
+00:41:21,280 --> 00:41:26,580
+R1 to R2 صح؟ وهذا اللي عمللي مشكلة crowding out،
+
+575
+00:41:26,580 --> 00:41:29,620
+بصبوط؟ صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح،
+
+576
+00:41:29,620 --> 00:41:29,620
+صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح،
+
+577
+00:41:29,620 --> 00:41:29,780
+صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح،
+
+578
+00:41:29,780 --> 00:41:31,300
+صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح،
+
+579
+00:41:31,300 --> 00:41:35,280
+صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح، صح،
+
+580
+00:41:35,280 --> 00:41:37,840
+صح، صح،
+
+581
+00:41:45,660 --> 00:41:49,040
+عشان ألغى التأثير لازم أزود ال money supply فخلينا
+
+582
+00:41:49,040 --> 00:41:53,740
+نشوف if the central bank or the federal reserve
+
+583
+00:41:53,740 --> 00:41:58,240
+system in this case used an expansionary monitor
+
+584
+00:41:58,240 --> 00:42:00,580
+policy by increasing the money supply شو اللي
+
+585
+00:42:00,580 --> 00:42:05,020
+بيصير في ال prices؟
+
+586
+00:42:05,020 --> 00:42:09,540
+خلينا نشوف yes مين عندهم؟ yes محمد you have؟ طيب
+
+587
+00:42:09,540 --> 00:42:16,220
+so let's useأو دعنا نعتمد على أن الشركة الأساسية
+
+588
+00:42:16,220 --> 00:42:24,720
+استعملت قياسية تدخلية تدخل الأموال بإزالة تدخل
+
+589
+00:42:24,720 --> 00:42:28,180
+الأموال لتغيير
+
+590
+00:42:28,180 --> 00:42:36,380
+تأثير تدخل الأموال بإزالة تدخل الأموال بإزالة تدخل
+
+591
+00:42:36,380 --> 00:42:37,900
+الأموال لتغيير تدخل الأموال
+
+592
+00:42:44,480 --> 00:42:48,920
+decrease in the interest rate increase I increase
+
+593
+00:42:48,920 --> 00:42:52,940
+aggregate expenditure or increase aggregate demand
+
+594
+00:42:52,940 --> 00:42:55,700
+so in this case the aggregate demand would
+
+595
+00:42:55,700 --> 00:43:01,080
+increase once again شو اللي حيصير؟ the prices
+
+596
+00:43:01,080 --> 00:43:05,900
+would increase hyperinflation exactly يا بقى
+
+597
+00:43:05,900 --> 00:43:09,940
+hyperinflation اذا بعد ال full capacity هذا هيك
+
+598
+00:43:11,730 --> 00:43:15,870
+بيكون أصلا ال .. ال .. ال .. ال fiscal policy
+
+599
+00:43:15,870 --> 00:43:18,490
+neither the fiscal policy nor the monetary policy
+
+600
+00:43:18,490 --> 00:43:23,410
+is effective صح؟ لأنه خربوا الدنيا هيك، مظبوط ولا
+
+601
+00:43:23,410 --> 00:43:28,230
+لأ؟ لأنه خربت هيك، لأنه زيادات اللي صارت في ال
+
+602
+00:43:28,230 --> 00:43:30,370
+fiscal policy، ال expansion of fiscal policy، شو
+
+603
+00:43:30,370 --> 00:43:32,690
+عملتوا ال prices؟ طلعتوا، وال expansion of
+
+604
+00:43:32,690 --> 00:43:37,770
+monetary policy increased the prices صح؟ واضحة ولا
+
+605
+00:43:37,770 --> 00:43:41,830
+فيها مشاكل؟إيه؟ طب مين حابب يعيدله الجزئية
+
+606
+00:43:41,830 --> 00:43:47,950
+والموضوع هذا؟ إذا if the federal الحل إنه يرجع
+
+607
+00:43:47,950 --> 00:43:53,730
+لوين إنه إذا كنا بعد ال full capacity المفروض إنه
+
+608
+00:43:53,730 --> 00:43:56,230
+ماستخدمش expansion of fiscal ولا expansion of
+
+609
+00:43:56,230 --> 00:44:04,910
+monetary policy شوف
+
+610
+00:44:04,910 --> 00:44:11,390
+no .. no .. no .. no ..يعني the increasing the
+
+611
+00:44:11,390 --> 00:44:14,250
+government spending is ineffective, so they will
+
+612
+00:44:14,250 --> 00:44:20,770
+spend money without effects, without impacts on
+
+613
+00:44:20,770 --> 00:44:21,290
+the economy
+
+614
+00:44:24,260 --> 00:44:30,320
+وهو ممكن يخلق مقاومة في الميزانية ويخلق زيادة في
+
+615
+00:44:30,320 --> 00:44:34,740
+ميزانية الانفلات بدون امبارحات بدون امبارحات
+
+616
+00:44:34,740 --> 00:44:34,760
+امبارحات امبارحات امبارحات امبارحات امبارحات
+
+617
+00:44:34,760 --> 00:44:37,920
+امبارحات امبارحات امبارحات امبارحات
+
+618
+00:44:39,930 --> 00:44:43,650
+The interest rate on a change by increasing the
+
+619
+00:44:43,650 --> 00:44:46,690
+money supply هذا التحليل اللي عملناه الجد انه بدون
+
+620
+00:44:46,690 --> 00:44:49,330
+ميثابته سعر الفائدة by increasing the money supply
+
+621
+00:44:49,330 --> 00:44:53,430
+the aggregate demand curve will shift further and
+
+622
+00:44:53,430 --> 00:44:56,950
+further to the right the result would be a
+
+623
+00:44:56,950 --> 00:45:01,430
+sustained inflation اللي هو sustained inflation or
+
+624
+00:45:01,430 --> 00:45:04,230
+hyperinflation يعطيكم العافية
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/5gD1DD1d5g0_postprocess.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/5gD1DD1d5g0_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..403296e88b4f235b6a657daabcbc638c68c9e9d7
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/5gD1DD1d5g0_postprocess.srt
@@ -0,0 +1,2200 @@
+1
+00:00:20,920 --> 00:00:24,300
+Okay بسم الله الرحمن الرحيم اليوم إن شاء الله سوف
+
+2
+00:00:24,300 --> 00:00:32,200
+نكمل الحلقة الثانية و سنبدأ في حلقة الثالثة كما
+
+3
+00:00:32,200 --> 00:00:38,580
+تعلمين في السلسلة الأخيرةقررنا الاختلافات بين GDP
+
+4
+00:00:38,580 --> 00:00:46,380
+نمو و GDP حقيقي و كيفية تخطيط نمو و GDP حقيقي و
+
+5
+00:00:46,380 --> 00:00:52,540
+GDP الانفجار اليوم
+
+6
+00:00:52,540 --> 00:00:58,340
+كما ذكرت أننا سنكمل شيء
+
+7
+00:00:58,340 --> 00:01:06,520
+مرتبط بـ Chapter 2 ثم نبدأ في Chapter 3كما ترى أو
+
+8
+00:01:06,520 --> 00:01:10,320
+كما تعلمين أن الـ GDP الحقيقي يتخيل أو يقوم
+
+9
+00:01:10,320 --> 00:01:13,440
+باستخدام
+
+10
+00:01:13,440 --> 00:01:18,840
+ماذا؟ السعر الحقيقي أو السعر الحقيقي؟ الـ GDP
+
+11
+00:01:18,840 --> 00:01:23,480
+الحقيقي؟ نعم بالضبط، لكن الـ GDP الحقيقي يقوم
+
+12
+00:01:23,480 --> 00:01:27,600
+باستخدام ماذا؟
+
+13
+00:01:27,600 --> 00:01:29,620
+باستخدام السعر الحقيقي،
+
+14
+00:01:33,060 --> 00:01:42,300
+لنذهب الى GDP و الاجتماعي كما تعلمينعندما نتحدث عن
+
+15
+00:01:42,300 --> 00:01:49,080
+GDP نحن نتحدث عن اجرس أو جميع الاختصارات التي
+
+16
+00:01:49,080 --> 00:01:52,180
+تنتجت في وقت مضى وقت مضى وقت مضى وقت مضى وقت مضى
+
+17
+00:01:52,180 --> 00:01:53,800
+وقت مضى وقت مضى وقت مضى وقت مضى وقت مضى وقت مضى
+
+18
+00:01:53,800 --> 00:01:54,860
+وقت مضى وقت مضى وقت مضى وقت مضى وقت مضى وقت مضى
+
+19
+00:01:54,860 --> 00:01:55,220
+وقت مضى وقت مضى وقت مضى وقت مضى وقت مضى وقت مضى
+
+20
+00:01:55,220 --> 00:01:58,680
+وقت مضى وقت مضى وقت مضى وقت مضى وقت مضى وقت مضى
+
+21
+00:01:58,680 --> 00:02:07,040
+وقت مضى وقت مضى وقت
+
+22
+00:02:07,070 --> 00:02:12,530
+إذا تحسن حالة الاقتصاد أو الاجتماع، فهذا سيحسن
+
+23
+00:02:12,530 --> 00:02:17,470
+حالة
+
+24
+00:02:17,470 --> 00:02:26,770
+الاجتماع للناسمثلًا، إذا كانت قيمة الحقوق تتخلص
+
+25
+00:02:26,770 --> 00:02:31,910
+من المجتمع، في هذه الحالة، ماذا سيحدث؟ سيزداد
+
+26
+00:02:31,910 --> 00:02:36,910
+الهجوم الاجتماعي، ولكن GDP لا يتحدث عن اهتمام
+
+27
+00:02:36,910 --> 00:02:43,750
+الهجوم على الاقتصاد، لذلك التخطيط GDP لديه مشاكل
+
+28
+00:02:45,150 --> 00:02:53,650
+وهو يغيّر تأثير الوظيفة الاجتماعية ويغيّر انه
+
+29
+00:02:53,650 --> 00:02:58,670
+يتحدث عن تنمية هذا الوصول في بعض الأحيان كله أو
+
+30
+00:02:58,670 --> 00:03:05,670
+ربما 70% من هذا الوصول سيكون أو سيذهب إلى مجموعة
+
+31
+00:03:05,670 --> 00:03:11,270
+من 10% من المجتمع لذلك لا يتحدث عن تنمية الوظيفة
+
+32
+00:03:11,270 --> 00:03:19,080
+ماذا عنلذلك، كما تشاهدين، الجي دي بي مرتبط
+
+33
+00:03:19,080 --> 00:03:22,120
+بـSocial Welfare Society كمصطلح لتخلص السحب عند
+
+34
+00:03:22,120 --> 00:03:27,520
+تخلص السحب، ولكن تخلص السحب ليس موجودًا في الجي دي
+
+35
+00:03:27,520 --> 00:03:35,360
+بي، فالجي دي بي لا يهتم بسحب السحب في المجتمع، ما
+
+36
+00:03:35,360 --> 00:03:39,350
+هو أخر؟An increase in the leisure, leisure means
+
+37
+00:03:39,350 --> 00:03:43,550
+الراحة أو وقت الفراغ is an increase in social
+
+38
+00:03:43,550 --> 00:03:49,510
+welfare but not counted in GDP So the social
+
+39
+00:03:49,510 --> 00:03:56,930
+welfare is not reflected in the GDP What else؟ The
+
+40
+00:03:56,930 --> 00:03:59,550
+production of your .. or the activities are
+
+41
+00:03:59,550 --> 00:04:04,730
+implemented by your mother at home It's part of
+
+42
+00:04:04,730 --> 00:04:09,340
+the productionولكنها ليست مفهومة في GDP، لذلك في
+
+43
+00:04:09,340 --> 00:04:17,040
+بعض الأحيان أشياء مختلفة ليست مفهومة في GDP، لذلك
+
+44
+00:04:17,040 --> 00:04:23,900
+لديها مشكلة، كما تعلمين إن إذا أمك تقدر تقدر تقدر
+
+45
+00:04:23,900 --> 00:04:24,160
+تقدر تقدر تقدر تقدر تقدر تقدر تقدر تقدر تقدر تقدر
+
+46
+00:04:24,160 --> 00:04:24,300
+تقدر تقدر تقدر تقدر تقدر تقدر تقدر تقدر تقدر تقدر
+
+47
+00:04:24,300 --> 00:04:25,220
+تقدر تقدر تقدر تقدر تقدر تقدر تقدر تقدر تقدر تقدر
+
+48
+00:04:25,220 --> 00:04:30,900
+تقدرفكل هذه المساعدات التي تم إعطائها أمك لأطفالها
+
+49
+00:04:30,900 --> 00:04:37,720
+و لأطفالها ليست مفهومة في GDP فهي
+
+50
+00:04:37,720 --> 00:04:44,420
+يجب أن تكون مفهومة لكي تكون صحيحة كما ترى في
+
+51
+00:04:44,420 --> 00:04:50,430
+النقطة الثالثة فإن مجتمعات ومجتمعاتالأنشطة اللي
+
+52
+00:04:50,430 --> 00:04:53,550
+بتكون بتعملها إما في البيت مابترا حاسبش ضمن ال GDP
+
+53
+00:04:53,550 --> 00:04:57,430
+So activities are not counted in the GDP even
+
+54
+00:04:57,430 --> 00:05:01,330
+though they amount of the real production What
+
+55
+00:05:01,330 --> 00:05:07,290
+else GDP as I mentioned has nothing to say about
+
+56
+00:05:07,290 --> 00:05:12,380
+the distribution of outputSo it doesn't talk about
+
+57
+00:05:12,380 --> 00:05:15,140
+the distribution of income and outputs in the
+
+58
+00:05:15,140 --> 00:05:20,060
+community.So إذا في عندنا مجموعة مشاكل في ال GDP
+
+59
+00:05:20,060 --> 00:05:23,820
+وإن كان هو وضع هو كويس بيعطي مؤشر it's a good
+
+60
+00:05:23,820 --> 00:05:27,300
+indicator for the health of the economy but it has
+
+61
+00:05:27,300 --> 00:05:33,710
+or it ignoresشيء مرتبط بـ Social Welfare ، الخطوات
+
+62
+00:05:33,710 --> 00:05:41,250
+في الاقتصاد والتطبيقات أو التطبيقات في المجتمع ،
+
+63
+00:05:41,250 --> 00:05:44,350
+فهو لا يعتمد على تطبيقات الاتصال والتطبيقات في
+
+64
+00:05:44,350 --> 00:05:52,330
+الاقتصاد، صحيح؟ لذلك، لكي تكون صحيح، يجب أن تعتمد
+
+65
+00:05:52,330 --> 00:05:55,650
+على هذه الأشياء، صحيح؟ عشان هيك في ناس قالوا ان
+
+66
+00:05:55,650 --> 00:06:02,090
+الـ GDP مش مؤشر كويس للاقتصادلأنه أهمل الحاجات هذه
+
+67
+00:06:02,090 --> 00:06:06,050
+أهمل اللي هو التوزيع الداخل أهمل ال .. ال .. the
+
+68
+00:06:06,050 --> 00:06:10,950
+activities implemented by the .. the households or
+
+69
+00:06:10,950 --> 00:06:16,830
+something like this okay let's go to another thing
+
+70
+00:06:16,830 --> 00:06:22,390
+which is the underground economy yes the plaque
+
+71
+00:06:22,390 --> 00:06:28,400
+market باختصار ال underground economyهو الاقتصاد
+
+72
+00:06:28,400 --> 00:06:31,740
+السنوي عمليا الانشطة بتصير وفيه انه real
+
+73
+00:06:31,740 --> 00:06:36,480
+production بس مابتتسجلش في ال GDP and we have an
+
+74
+00:06:36,480 --> 00:06:40,060
+example which is the tax evasion تهرب الضريبي
+
+75
+00:06:40,060 --> 00:06:45,240
+عمليا .. عمليا الانشطة تنفذ اللي هو ال .. و فيه
+
+76
+00:06:45,240 --> 00:06:50,340
+actual production but it is not registered in the
+
+77
+00:06:50,340 --> 00:06:57,910
+GDPالعامة الـ GDP لا تحتوي على كل شيء في الاقتصاد،
+
+78
+00:06:57,910 --> 00:07:02,450
+في بعض الأحيان لدينا بعض الأعمال، بعض الأعمال، بعض
+
+79
+00:07:02,450 --> 00:07:07,390
+المصادرالتي تم تطبيقها بالفعل ولكنها لم تدخل في
+
+80
+00:07:07,390 --> 00:07:12,910
+تخصيص الـ GDP كما تشاهد الـ Tax Evasions فكما
+
+81
+00:07:12,910 --> 00:07:15,390
+تشاهد الـ Underground Economy يعني الاقتصاد السرري
+
+82
+00:07:15,390 --> 00:07:20,530
+هو جزء من اجتماعية في التي تحدث التعاملات
+
+83
+00:07:20,530 --> 00:07:28,030
+المبادلات والمعاملات بتصير حقيقة وفي المجموعات
+
+84
+00:07:28,030 --> 00:07:35,410
+التي تم تجريها بالفعللكن هذا غير مقال و لذلك ليس
+
+85
+00:07:35,410 --> 00:07:42,190
+مقال في الـ GDP، صحيح؟ فعملياً فيه أنشطة بتصير
+
+86
+00:07:42,190 --> 00:07:48,790
+وفيه income generated ولكن .. أو للأسف ليس مقال أو
+
+87
+00:07:48,790 --> 00:07:54,210
+تسجل في الـ GDP لذلك بعض الأعمال الاقتصادية ليست
+
+88
+00:07:54,210 --> 00:07:59,030
+مقالة أو غير مقالة في الاقتصاد أو في الـ GDPعند
+
+89
+00:07:59,030 --> 00:08:05,710
+تخطيطها و لدينا مثلًا وهو تخطيط التجارب التجارب
+
+90
+00:08:05,710 --> 00:08:10,850
+التجارب التجارب التجارب التجارب التجارب التجارب
+
+91
+00:08:10,850 --> 00:08:10,890
+التجارب التجارب التجارب التجارب التجارب التجارب
+
+92
+00:08:10,890 --> 00:08:10,910
+التجارب التجارب التجارب التجارب التجارب التجارب
+
+93
+00:08:10,910 --> 00:08:11,130
+التجارب التجارب التجارب التجارب التجارب التجارب
+
+94
+00:08:11,130 --> 00:08:21,250
+الت
+
+95
+00:08:22,130 --> 00:08:25,970
+Usually thought to be the major incentive for
+
+96
+00:08:25,970 --> 00:08:30,950
+people to practice in the underground economy و ال
+
+97
+00:08:30,950 --> 00:08:35,010
+black market as your classmate explained it, it's
+
+98
+00:08:35,010 --> 00:08:40,670
+one of the examples for the underground economy
+
+99
+00:08:45,640 --> 00:08:51,780
+هنا لدينا كلمة مرتبطة بـ GDP وهو Gross National
+
+100
+00:08:51,780 --> 00:08:59,520
+Income Gross National Income لنقوم بمقارنة بين
+
+101
+00:08:59,520 --> 00:09:07,750
+الوضع الاقتصادي بين البلدان المختلفةمثلا اذا كنت
+
+102
+00:09:07,750 --> 00:09:15,390
+اريد ان اقارن بين الاقتصاد الأمريكي و الاقتصاد
+
+103
+00:09:15,390 --> 00:09:22,050
+الولايات المتحدة، يجب ان استخدم ايقاع مميز لأقارن
+
+104
+00:09:22,880 --> 00:09:31,380
+بشكل عام، يستخدمون الميزة الوطنية كإشارة لتقارير
+
+105
+00:09:31,380 --> 00:09:38,760
+الوضع الاقتصادي في هذه الأمريكا. لذلك، في هذه
+
+106
+00:09:38,760 --> 00:09:42,780
+الحالة، يجب أن نقوم بإتصال، كما ترى، بميزة
+
+107
+00:09:42,780 --> 00:09:43,200
+الولايات المتحدة.
+
+108
+00:09:46,350 --> 00:09:50,350
+to for their transactions بيستخدموا ال pound لجنيه
+
+109
+00:09:50,350 --> 00:09:54,490
+السترليني مظبوط in the US they used the US dollar
+
+110
+00:09:54,490 --> 00:09:58,650
+right or suppose in Israel suppose that we are
+
+111
+00:09:58,650 --> 00:10:01,110
+going to do a comparison between the Israeli
+
+112
+00:10:01,110 --> 00:10:05,430
+economy and the UK economy as you as you know that
+
+113
+00:10:05,430 --> 00:10:09,410
+the in the Israeli economy they use شكل in you
+
+114
+00:10:09,410 --> 00:10:14,300
+Israeli شكلللتعامل مع اجتماعاتهم ومصالحهم ومصالحهم
+
+115
+00:10:14,300 --> 00:10:19,460
+لتعامل مع GDP في الولايات المتحدة يستخدمون كمية
+
+116
+00:10:19,460 --> 00:10:23,460
+لتعامل مع اجتماعاتهم في الولايات المتحدة يستخدمون
+
+117
+00:10:23,460 --> 00:10:23,920
+كمية لتعامل مع اجتماعاتهم في الولايات المتحدة
+
+118
+00:10:23,920 --> 00:10:26,040
+يستخدمون كمية لتعامل مع اجتماعاتهم في الولايات
+
+119
+00:10:26,040 --> 00:10:28,220
+المتحدة يستخدمون كمية لتعامل مع اجتماعاتهم في
+
+120
+00:10:28,220 --> 00:10:28,420
+الولايات المتحدة يستخدمون كمية لتعامل مع
+
+121
+00:10:28,420 --> 00:10:30,960
+لتعامل مع اجتماعاتهم في الولايات المتحدة يستأو
+
+122
+00:10:30,960 --> 00:10:35,440
+مصادر تقارير تسمى جي ن اي مصادر تقارير مصادر
+
+123
+00:10:35,440 --> 00:10:36,140
+تقارير مصادر تقارير مصادر تقارير مصادر تقارير
+
+124
+00:10:36,140 --> 00:10:38,020
+مصادر تقارير مصادر تقارير مصادر تقارير مصادر
+
+125
+00:10:38,020 --> 00:10:39,880
+تقارير مصادر تقارير مصادر تقارير مصادر تقارير
+
+126
+00:10:39,880 --> 00:10:41,000
+مصادر تقارير مصادر تقارير مصادر تقارير مصادر
+
+127
+00:10:41,000 --> 00:10:41,320
+تقارير مصادر تقارير مصادر تقارير مصادر تقارير
+
+128
+00:10:41,320 --> 00:10:43,080
+مصادر تقارير مصادر تقارير مصادر تقارير مصادر
+
+129
+00:10:43,080 --> 00:10:52,400
+تقارير مصادر تقارير مصادر تقارير مصادر
+
+130
+00:10:52,400 --> 00:10:57,870
+تققمنا بإعادة قيمة الـ GDP أو قيمة الوصول إلى
+
+131
+00:10:57,870 --> 00:11:01,270
+دولار الولايات المتحدة من شكل إلى دولار الولايات
+
+132
+00:11:01,270 --> 00:11:08,150
+المتحدة على سبيل المثال شكل إسرائيلي جديد او احد
+
+133
+00:11:08,150 --> 00:11:17,850
+دولار الولايات المتحدة يعني كم دولار؟ 3.7
+
+134
+00:11:17,850 --> 00:11:19,950
+دولار شكل إسرائيلي جديد
+
+135
+00:11:24,260 --> 00:11:29,760
+والنسبة للأموال المجاورة أو المجاورة الأمريكية
+
+136
+00:11:29,760 --> 00:11:31,700
+والمجاورة الأمريكية والمجاورة الأمريكية والمجاورة
+
+137
+00:11:31,700 --> 00:11:33,320
+الأمريكية والمجاورة الأمريكية والمجاورة الأمريكية
+
+138
+00:11:33,320 --> 00:11:35,460
+والمجاورة الأمريكية والمجاورة الأمريكية والمجاورة
+
+139
+00:11:35,460 --> 00:11:35,480
+الأمريكية والمجاورة الأمريكية والمجاورة الأمريكية
+
+140
+00:11:35,480 --> 00:11:41,280
+والمجاورة الأمريكية والمجاورة الأمريكية والمجاورة
+
+141
+00:11:41,280 --> 00:11:42,100
+الأمريكية
+
+142
+00:11:48,770 --> 00:12:00,750
+1 USD ايقاز كم رمز 0.7 سببوز هذا رمز الولايات
+
+143
+00:12:00,750 --> 00:12:04,550
+المتحدة و
+
+144
+00:12:04,550 --> 00:12:14,250
+سببوز ان ال GDP او الاستخدام الوطني في الولايات
+
+145
+00:12:14,250 --> 00:12:18,050
+المتحدة سببوز كان 7
+
+146
+00:12:19,190 --> 00:12:23,990
+مليون تاوزن تاوزن
+
+147
+00:12:23,990 --> 00:12:31,370
+تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن
+
+148
+00:12:31,370 --> 00:12:35,990
+تاوزن
+
+149
+00:12:35,990 --> 00:12:39,430
+تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن
+
+150
+00:12:39,430 --> 00:12:41,090
+تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن
+
+151
+00:12:41,090 --> 00:12:41,210
+تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن
+
+152
+00:12:41,210 --> 00:12:42,970
+تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن تاوزن
+
+153
+00:12:42,970 --> 00:12:48,230
+تاوزن تاوزن ت
+
+154
+00:12:49,990 --> 00:12:55,050
+وهذا في دولار الولايات المتحدة ويجب أن نقرر أيه
+
+155
+00:12:55,050 --> 00:13:01,450
+أفضل، الإسرائيل أو الإيقان الأمريكي. لذلك، دعونا
+
+156
+00:13:01,450 --> 00:13:08,390
+نعود إلى مفهوم الوزراء الوطني. كما ترى، لتقارير
+
+157
+00:13:08,390 --> 00:13:12,690
+الـGDP بين البلدين، يجب أن يكون حجم التغيير
+
+158
+00:13:12,690 --> 00:13:20,000
+الكورانسيكي تعتمد على أسعار الصرف.إنه منحول من شيك
+
+159
+00:13:20,000 --> 00:13:23,840
+لدولار من UK pound لدولار so the gross national
+
+160
+00:13:23,840 --> 00:13:26,840
+income is a measure used to make what
+
+161
+00:13:26,840 --> 00:13:32,880
+international comparisonsoutput GMI is GNP
+
+162
+00:13:32,880 --> 00:13:36,880
+converted into dollar into US dollar using an
+
+163
+00:13:36,880 --> 00:13:39,960
+average of currency exchange rate over several
+
+164
+00:13:39,960 --> 00:13:43,280
+years adjusted for the rate of inflation بحطول
+
+165
+00:13:43,280 --> 00:13:48,860
+بنعمل exchange rate ما بين الشكل للدولار و ال UK
+
+166
+00:13:48,860 --> 00:13:54,640
+pound للدولار و بنشوف which is better right so
+
+167
+00:14:04,440 --> 00:14:09,320
+متوسط نصيب الفرد من إجمالي الدخل القومي عبارة عن
+
+168
+00:14:09,320 --> 00:14:12,580
+ال GMI الـ Gross National Income Over Population
+
+169
+00:14:12,580 --> 00:14:17,440
+يعني اعتبار ان ال G .. ال Gross National Income ال
+
+170
+00:14:17,440 --> 00:14:23,400
+GMI equal one thousand million dollar one thousand
+
+171
+00:14:23,400 --> 00:14:27,230
+dollar او one thousand million dollarوالنسبة
+
+172
+00:14:27,230 --> 00:14:37,550
+للجمهورية هي 2 مليون دولار USD ونسبة
+
+173
+00:14:37,550 --> 00:14:40,050
+للجمهورية هي 2 مليون
+
+174
+00:14:46,640 --> 00:14:54,340
+في هذه الحالة مطاوصة
+
+175
+00:14:54,340 --> 00:14:56,620
+نصيب الفرد من ال GNI مطاوصة نصيب الفرد من ال GNI
+
+176
+00:14:56,620 --> 00:14:58,080
+مطاوصة نصيب الفرد من ال GNI مطاوصة نصيب الفرد من
+
+177
+00:14:58,080 --> 00:14:59,080
+ال GNI مطاوصة نصيب الفرد من ال GNI مطاوصة نصيب
+
+178
+00:14:59,080 --> 00:15:00,640
+الفرد من ال GNI مطاوصة نصيب الفرد من ال GNI مطاوصة
+
+179
+00:15:00,640 --> 00:15:01,760
+نصيب الفرد من ال GNI مطاوصة نصيب الفرد من ال GNI
+
+180
+00:15:01,760 --> 00:15:06,780
+مطاوصة
+
+181
+00:15:06,780 --> 00:15:09,900
+نصيب الفرد من ال GNI مطاوصة نصيب الفرد من ال GNI
+
+182
+00:15:09,900 --> 00:15:14,100
+مطاوصة نصيب الفرد من ال GNI مطاوصة
+
+183
+00:15:14,100 --> 00:15:15,000
+نصيب الفرد من
+
+184
+00:15:18,030 --> 00:15:30,010
+1000 اكتر من 2500 دولار هذا هو المال المشارك للشخص
+
+185
+00:15:30,010 --> 00:15:35,650
+المشارك أو الشخص المشارك في الاقتصاد دعونا نبدأ أو
+
+186
+00:15:35,650 --> 00:15:40,470
+نبدأ بخطة 3 وهي المشاركات المستمرة والمستقبلية
+
+187
+00:15:40,470 --> 00:15:45,790
+المشاركة المشاركة المستمرة والمشاركة المشاركة
+
+188
+00:15:45,790 --> 00:15:46,150
+المشاركة المشاركة المشاركة المشاركة المشاركة
+
+189
+00:15:46,150 --> 00:15:46,190
+المشاركة المشاركة المشاركة المشاركة المشاركة
+
+190
+00:15:46,190 --> 00:15:46,210
+المشاركة المشاركة المشاركة المشاركة المشاركة
+
+191
+00:15:46,210 --> 00:15:46,270
+المشاركة المشاركة المشاركة المشاركة المشاركة الم
+
+192
+00:15:53,770 --> 00:16:00,530
+العامة الإيديالية تحتوى على الـ Pests أو الـ
+
+193
+00:16:00,530 --> 00:16:04,730
+Optimal أو العامة الإيديالية التي تحتوي على نسبة
+
+194
+00:16:04,730 --> 00:16:08,150
+نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة
+
+195
+00:16:08,150 --> 00:16:08,490
+نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة
+
+196
+00:16:08,490 --> 00:16:09,490
+نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة
+
+197
+00:16:09,490 --> 00:16:09,530
+نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة نسبة
+
+198
+00:16:09,530 --> 00:16:14,890
+نسبة نأفضل اقتصاد بدنا ياه low the economy with
+
+199
+00:16:14,890 --> 00:16:20,330
+low inflation rate معدل التدخم متدني low
+
+200
+00:16:20,330 --> 00:16:25,710
+unemployment rate and high growth rate so as you
+
+201
+00:16:25,710 --> 00:16:29,230
+see an ideal economy is one which in which there
+
+202
+00:16:29,230 --> 00:16:32,330
+is rapid growth of output per worker low
+
+203
+00:16:32,330 --> 00:16:35,710
+unemployment and low inflation rate right
+
+204
+00:16:41,990 --> 00:16:49,530
+النظرية النمو خلينا نشوف نظرية
+
+205
+00:16:49,530 --> 00:16:56,470
+النمو نظرية النمو نظرية النمو نظرية النمو نظرية
+
+206
+00:16:56,470 --> 00:16:59,230
+النمو نظرية النمو نظرية النمو نظرية النمو نظرية
+
+207
+00:16:59,230 --> 00:17:00,170
+النمو نظرية النمو نظرية النمو نظرية النمو نظرية
+
+208
+00:17:00,170 --> 00:17:00,310
+النمو نظرية النمو نظرية النمو نظرية النمو نظرية
+
+209
+00:17:00,310 --> 00:17:01,810
+النمو نظرية النمو نظرية النمو نظرية النمو نظرية
+
+210
+00:17:01,810 --> 00:17:08,380
+النمو نظرية النمبدنا نشوف العوامل اللي بتأثر فيه
+
+211
+00:17:08,380 --> 00:17:15,600
+النمو We have many factors affect the growth rate
+
+212
+00:17:15,600 --> 00:17:18,480
+in the economy Number one, the number of workers
+
+213
+00:17:18,480 --> 00:17:22,940
+If the number of workers increased, this leads to
+
+214
+00:17:22,940 --> 00:17:29,460
+increasing outputأو ارتفاع المصادر، هذا هو أول
+
+215
+00:17:29,460 --> 00:17:33,660
+مصادر تأثير ارتفاع المصادر في الاقتصاد أو ارتفاع
+
+216
+00:17:33,660 --> 00:17:39,540
+المصادر، ما هو أخر؟ نستطيع أن نضيف أكتر مصادر،
+
+217
+00:17:39,540 --> 00:17:44,840
+حسنا، لكن هنا عندما نتحدث عن نظر ارتفاع، نتحدث عن
+
+218
+00:17:44,840 --> 00:17:51,530
+المصادر وليس المصادرالسؤال الرئيسي هو كيف يمكننا
+
+219
+00:17:51,530 --> 00:17:54,630
+أن نزعج نتيجة الانتجار؟ نستطيع أن نضيف أكتر
+
+220
+00:17:54,630 --> 00:17:58,250
+عاملين، نستطيع أن نضيف أكتر سيارات، نستطيع أن نحسن
+
+221
+00:17:58,250 --> 00:18:04,130
+قيمة أو إنتجة العاملين وإنتجة السيارات بالتأكيد،
+
+222
+00:18:04,130 --> 00:18:08,250
+لذلك لدينا أربع أشكال أساسية أو خمس أشكال أساسية
+
+223
+00:18:08,250 --> 00:18:10,690
+تأثير الانتجار
+
+224
+00:18:12,730 --> 00:18:17,490
+ممكن نضيف أكتر عمال و نضيف أكتر أجهزة و نضيف أكتر
+
+225
+00:18:17,490 --> 00:18:20,570
+عمال و نضيف أكتر عمال و نضيف أكتر عمال و نضيف أكتر
+
+226
+00:18:20,570 --> 00:18:22,770
+عمال و نضيف أكتر عمال و نضيف أكتر عمال و نضيف أكتر
+
+227
+00:18:22,770 --> 00:18:26,430
+عمال و نضيف أكتر عمال و نضيف أكتر عمال و نضيف أكتر
+
+228
+00:18:26,430 --> 00:18:26,450
+عمال و نضيف أكتر عمال و نضيف أكتر عمال و نضيف أكتر
+
+229
+00:18:26,450 --> 00:18:26,670
+عمال و نضيف أكتر عمال و نضيف أكتر عمال و نضيف أكتر
+
+230
+00:18:26,670 --> 00:18:34,570
+عمال و نضيف أكتر عمال و نضيف أكتر عمال ولكن إذا
+
+231
+00:18:34,570 --> 00:18:38,950
+وصلنا إلى مقاومة كامة أو استخدام مقاومة كام أو
+
+232
+00:18:38,950 --> 00:18:41,090
+استخدام مقاومة كامة أو استخدام مقاومة كامة أو
+
+233
+00:18:41,090 --> 00:18:42,410
+استخدام مقاومة كامة أو استخدام مقاومة كامة أو
+
+234
+00:18:42,410 --> 00:18:43,290
+استخدام مقاومة كامة أو استخدام مقاومة كامة أو
+
+235
+00:18:43,290 --> 00:18:43,590
+استخدام مقاومة كامة أو استخدام مقاومة كامة أو
+
+236
+00:18:43,590 --> 00:18:45,810
+استخدام مقاومة كامة أو استخدام مقاومة كامة أو
+
+237
+00:18:45,810 --> 00:18:46,110
+استخدام مقاومة كامة أو استخدام مقاومة كامة أو
+
+238
+00:18:46,110 --> 00:18:50,590
+استخدام مقاومة كامة أو استخدام مقاومة كامة أو
+
+239
+00:18:50,590 --> 00:18:55,990
+استخدام مقاومة كامة أولكن بعد تمويل الموظفة
+
+240
+00:18:55,990 --> 00:19:01,150
+تمامًا، نعم، وإزالة الوظيفة على العميل يؤدي إلى
+
+241
+00:19:01,150 --> 00:19:05,730
+تقليل، أحيانًا، لتقليل الوظيفة العاملة، لذلك
+
+242
+00:19:05,730 --> 00:19:10,730
+نستطيع إزالة عدد الساعات التي عملها العميل كذلك
+
+243
+00:19:10,730 --> 00:19:15,790
+نستطيع إزالة قيمة أو إنتجة العميل وإنتجة الأجهزة
+
+244
+00:19:15,790 --> 00:19:19,210
+أو التكنولوجيا، نعم
+
+245
+00:19:23,500 --> 00:19:27,240
+نعم حسنا عندما نتكلم عن إزالة الأسلحة بالتأكيد
+
+246
+00:19:27,240 --> 00:19:33,120
+نتكلم عن الأسلحة الإزالة الأسلحة صحيح؟ كاستخدام
+
+247
+00:19:33,120 --> 00:19:38,080
+فكيف
+
+248
+00:19:38,080 --> 00:19:42,360
+يمكننا أن نتكلم عن أسلحة الاستخدام انتجيت العامل
+
+249
+00:19:42,360 --> 00:19:47,710
+شو بتساوي؟ كما ترى في هذه الفورمولةالـ labor
+
+250
+00:19:47,710 --> 00:19:51,290
+productivity إنتاجية العامل equal what؟ الـ total
+
+251
+00:19:51,290 --> 00:19:56,270
+output or the real GDP over the total worker hours
+
+252
+00:19:56,270 --> 00:20:00,330
+على عدد ساعات العامل، كده بننتج على عدد ساعات
+
+253
+00:20:00,330 --> 00:20:02,830
+العامل، this is what the labor productivity,
+
+254
+00:20:03,550 --> 00:20:09,890
+right؟لنعود إلى بعض المصطلحات التي قررناها في
+
+255
+00:20:09,890 --> 00:20:13,590
+الحلقة الأولى عملية السيكل ماهي عملية السيكل؟
+
+256
+00:20:13,590 --> 00:20:17,730
+بالضبط، إنها تقسيم الأعلى والأسفل في المشروع
+
+257
+00:20:17,730 --> 00:20:24,030
+الاقتصادي وعندما نتحدث عن عملية السيكل كما تعلمين،
+
+258
+00:20:24,030 --> 00:20:30,390
+كنا نتحدث عن اتفاق وانتقال أو اتفاق في المشروع
+
+259
+00:20:30,390 --> 00:20:32,910
+الاقتصادي، فقط لأذكرك
+
+260
+00:20:35,470 --> 00:20:54,830
+this is the business cycle right
+
+261
+00:20:54,830 --> 00:21:04,430
+this is the peak peak truth peak
+
+262
+00:21:05,960 --> 00:21:11,160
+from pig to trove we have what؟عادية بالضبط وهي
+
+263
+00:21:11,160 --> 00:21:15,280
+اتجارة في مدينة أو في هذه المدينة من مدينة إلى
+
+264
+00:21:15,280 --> 00:21:20,260
+مدينة الانتجارات ستزال تزال تزال تزال تزال تزال
+
+265
+00:21:20,260 --> 00:21:20,640
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+266
+00:21:20,640 --> 00:21:22,280
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+267
+00:21:22,280 --> 00:21:23,580
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+268
+00:21:23,580 --> 00:21:26,020
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+269
+00:21:26,020 --> 00:21:27,220
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+270
+00:21:27,220 --> 00:21:34,840
+تزال تزال تزال تزال
+
+271
+00:21:34,840 --> 00:21:38,580
+ت
+
+272
+00:21:39,140 --> 00:21:45,020
+لنذهب إلى الـ recession كما تعلم، الـ recession هو
+
+273
+00:21:45,020 --> 00:21:50,540
+مرحلة التي تتخلص الوصول الى الواقع والاستثمار
+
+274
+00:21:50,540 --> 00:21:56,500
+يزيد، يزداد، مظبوطة ولا لأ؟ لذلك، لنذهب إلى الوصول
+
+275
+00:21:56,500 --> 00:21:59,960
+الى الواقع هنا، الـ recession هي تقريبًا مرحلة
+
+276
+00:21:59,960 --> 00:22:03,920
+التي تتخلص حقيقة GDP كما ترى، في مرحلة الـ
+
+277
+00:22:03,920 --> 00:22:07,120
+recession هنا، الوصول
+
+278
+00:22:09,600 --> 00:22:15,780
+decline و ال unemployment increase لذلك في هذه
+
+279
+00:22:15,780 --> 00:22:20,300
+الحالة لدينا اقل او اتقال في الوظيفة المطلوبة في
+
+280
+00:22:20,300 --> 00:22:26,660
+هذه السنة صحيح؟ او في هذه المرحلة تمام؟ شو عندي
+
+281
+00:22:26,660 --> 00:22:33,240
+كمان بس نقطة اخيرة؟ ماذا؟ نقطة اخيرة؟ ماذا؟ ماذا؟
+
+282
+00:22:33,240 --> 00:22:33,440
+ماذا؟ ماذا؟ ماذا؟ ماذا؟ ماذا؟ ماذا؟ ماذا؟ ماذا؟
+
+283
+00:22:33,440 --> 00:22:36,200
+ماذا؟ ماذا؟ ماذا؟ ماذا؟ ماذا؟ ماذا؟ ماذا؟ ماذا؟
+
+284
+00:22:36,200 --> 00:22:42,250
+ماذانحن لدينا ماذا؟ اتفاق في الاقتصاد، نحن لدينا
+
+285
+00:22:42,250 --> 00:22:47,850
+عدد عملي كبير، عدد عملي كبير، عدد عملي كبير، عدد
+
+286
+00:22:47,850 --> 00:22:48,250
+عملي كبير، عدد عملي كبير، عدد عملي كبير، عدد عملي
+
+287
+00:22:48,250 --> 00:22:48,970
+كبير، عدد عملي كبير، عدد عملي كبير، عدد عملي كبير،
+
+288
+00:22:48,970 --> 00:22:49,750
+عدد عملي كبير، عدد عملي كبير، عدد عملي كبير، عدد
+
+289
+00:22:49,750 --> 00:22:50,310
+عملي كبير، عدد عملي كبير، عدد عملي كبير، عدد عملي
+
+290
+00:22:50,310 --> 00:22:54,170
+كبير، عدد عملي كبير، عدد عملي كبير، عدد عملي ك
+
+291
+00:22:57,370 --> 00:23:03,250
+كما تشاهد، القدرة على المستخدمين أو المطالبة
+
+292
+00:23:03,250 --> 00:23:10,920
+قليلة، وفي هذه الحالة، الشركات مضطرة تغلقلذلك، إذا
+
+293
+00:23:10,920 --> 00:23:15,520
+تذكر أن الـKeynesians أو الـMr. Keynes أدبّع
+
+294
+00:23:15,520 --> 00:23:23,060
+الحكومة لإشعال الاقتصاد بماذا؟ بإشعال المطالبة أو
+
+295
+00:23:23,060 --> 00:23:28,800
+بإزالة .. بالضبط يا محمد، بإزالة تكلفتها أو تقليل
+
+296
+00:23:28,800 --> 00:23:35,570
+المجالات لإشعال الاقتصاد أو لإزالة الانتجارهذه هي
+
+297
+00:23:35,570 --> 00:23:40,590
+السلوكية التي تم إعادتها من السيد كينز ما هي
+
+298
+00:23:40,590 --> 00:23:47,270
+الانتقال الانتقال كما ذكرنا اتقالين او اتقالات
+
+299
+00:23:47,270 --> 00:23:52,880
+مستمرينbecomes what؟ a depression بس مرحلتين و
+
+300
+00:23:52,880 --> 00:23:57,220
+تالتين من اللي هو اللي هي بيصير انها depression او
+
+301
+00:23:57,220 --> 00:24:00,800
+a prolonged and deep recession becomes a
+
+302
+00:24:00,800 --> 00:24:04,380
+depression what else؟ the capacity utilization
+
+303
+00:24:04,380 --> 00:24:11,730
+rateبسموه معدل المستخدم من الطاقة suppose that we
+
+304
+00:24:11,730 --> 00:24:15,010
+have in the palestinian economy the capacity
+
+305
+00:24:15,010 --> 00:24:23,150
+utilization is suppose we have a 1000 worker if we
+
+306
+00:24:23,150 --> 00:24:29,230
+used 800 workers in this case we used how much 80
+
+307
+00:24:29,230 --> 00:24:34,990
+percent out of our capacityإذا استخدمنا الألف يكون
+
+308
+00:24:34,990 --> 00:24:39,790
+في وين احنا؟ full capacity utilization suppose انه
+
+309
+00:24:39,790 --> 00:24:43,730
+.. انه in an economy we have one thousand workers
+
+310
+00:24:43,730 --> 00:24:51,410
+and this economy used only seven hundred workers
+
+311
+00:24:54,350 --> 00:24:59,470
+قدش ان ال capacity utilization rate exactly so the
+
+312
+00:24:59,470 --> 00:25:02,850
+capacity utilization rate equals seven hundred
+
+313
+00:25:02,850 --> 00:25:07,310
+over one thousand times one hundred equals seventy
+
+314
+00:25:07,310 --> 00:25:08,570
+percent
+
+315
+00:25:11,800 --> 00:25:16,180
+هذا ايش اسمه ال capacity utilization rate وهو
+
+316
+00:25:16,180 --> 00:25:20,920
+الجزء المستغل من الطاقة تبعتنا if we use more
+
+317
+00:25:20,920 --> 00:25:23,920
+workers in this case the capacity utilization rate
+
+318
+00:25:23,920 --> 00:25:24,940
+would increase
+
+319
+00:25:33,670 --> 00:25:39,730
+إذا كنا نستخدم أكتر عملاء أو أكتر عاملين للصناعة،
+
+320
+00:25:39,730 --> 00:25:42,750
+فإن استخدام عملياتنا ستزال يزال يزال يزال يزال
+
+321
+00:25:42,750 --> 00:25:45,210
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+322
+00:25:45,210 --> 00:25:47,250
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+323
+00:25:47,250 --> 00:25:48,610
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+324
+00:25:48,610 --> 00:26:01,910
+يزال يزال يزال يزال يزال يز
+
+325
+00:26:02,610 --> 00:26:06,470
+right يعني لازم الأصل أن احنا نستخدم طاقة أعلى
+
+326
+00:26:06,470 --> 00:26:07,350
+okay
+
+327
+00:26:13,530 --> 00:26:17,670
+Okay let's go to the definition or the differences
+
+328
+00:26:17,670 --> 00:26:22,790
+between employed people and unemployed people اللي
+
+329
+00:26:22,790 --> 00:26:26,370
+في تعريف للناس اللي بيشتغلوا وفي ناس اللي عطلين عن
+
+330
+00:26:26,370 --> 00:26:30,650
+العمل So let's go to distinguish between the
+
+331
+00:26:30,650 --> 00:26:34,950
+unemployed and employed people ال employed we have
+
+332
+00:26:34,950 --> 00:26:37,590
+three main conditions for the people to be
+
+333
+00:26:37,590 --> 00:26:43,400
+classified as employedفي عندى تلت حاجات تلت شروط
+
+334
+00:26:43,400 --> 00:26:46,880
+عشان يكونوا هدولة مصنفين ضمن ان هم بيشتغلوا number
+
+335
+00:26:46,880 --> 00:26:51,840
+one as you see the people who works for pay اللي
+
+336
+00:26:51,840 --> 00:26:57,960
+بندفعله أجار and either for someone else or in his
+
+337
+00:26:57,960 --> 00:27:01,660
+or her own business for one or more hours per week
+
+338
+00:27:01,660 --> 00:27:06,770
+واحد بندفعله أجار وبيشتغل ساعة أو أكتر في وينhis
+
+339
+00:27:06,770 --> 00:27:12,170
+own business or her own business اللي بيشتغل ساعة
+
+340
+00:27:12,170 --> 00:27:17,030
+او اكتر في شغله في الأسبوع تمام هذا يصنع is
+
+341
+00:27:17,030 --> 00:27:22,750
+classified as employed what else the people who
+
+342
+00:27:22,750 --> 00:27:27,790
+works without payfor fifteen or more hours per
+
+343
+00:27:27,790 --> 00:27:32,290
+week in a family enterprise واحد بندفعلوش أجر بس
+
+344
+00:27:32,290 --> 00:27:35,370
+بيشتغل خمستاشر ساعة أو أكتر في ال .. في ال .. في
+
+345
+00:27:35,370 --> 00:27:39,110
+ال business تبع العيلة هذا بيسموه employed what
+
+346
+00:27:39,110 --> 00:27:43,930
+else؟ the people who has a job but has been
+
+347
+00:27:43,930 --> 00:27:48,270
+temporarily absent with or without pay واحد بيشتغل
+
+348
+00:27:48,270 --> 00:27:53,010
+أصلا بس غايب عن الشغل ناخد إجازة تمام هذا بيسموه
+
+349
+00:27:53,010 --> 00:27:59,630
+employedSo what about the unemployed people or the
+
+350
+00:27:59,630 --> 00:28:06,710
+unemployed persons the unemployed persons is or
+
+351
+00:28:06,710 --> 00:28:11,670
+the unemployed person is a person 16 years old or
+
+352
+00:28:11,670 --> 00:28:16,790
+more who is not working يعني بدنا نصنف اللي هم
+
+353
+00:28:16,790 --> 00:28:20,890
+الناس اللي unemployed يصنفوا أولاشي 15 years old
+
+354
+00:28:20,890 --> 00:28:25,790
+or more and they are not workingis available for
+
+355
+00:28:25,790 --> 00:28:30,470
+work يعني عنده قدرة على العمل and has made
+
+356
+00:28:30,470 --> 00:28:33,970
+specific efforts to find work during the previous
+
+357
+00:28:33,970 --> 00:28:38,550
+four weeks but not found work يعني لازم يكون 16
+
+358
+00:28:38,550 --> 00:28:43,970
+years old or more he has available is available
+
+359
+00:28:43,970 --> 00:28:50,290
+for work he search for job during the last four
+
+360
+00:28:50,290 --> 00:28:52,130
+weeks and he didn't find
+
+361
+00:28:54,900 --> 00:28:57,960
+لأ انتوا بيسموكم discouraged workers جيلة هذا
+
+362
+00:28:57,960 --> 00:29:02,360
+المصطلح او اللي بيطلعوكوا من برا هدوله لأ مش
+
+363
+00:29:02,360 --> 00:29:05,920
+discouraged worker انتوا as a student you are not
+
+364
+00:29:05,920 --> 00:29:10,340
+in the labor force انتوا برا القوة العاملة لأنه
+
+365
+00:29:10,340 --> 00:29:14,120
+مابتبحثوش عن شغل yes not available for work you
+
+366
+00:29:14,120 --> 00:29:18,300
+didn't you don't search for a job so you are not
+
+367
+00:29:18,300 --> 00:29:21,460
+unemployed you are you are not unemployed exactly
+
+368
+00:29:21,460 --> 00:29:22,380
+so
+
+369
+00:29:25,040 --> 00:29:27,540
+أو ما بيشتغلوش بيعدلوا ال student ما خدوا فوق
+
+370
+00:29:27,540 --> 00:29:29,760
+السنتاشر لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ
+
+371
+00:29:29,760 --> 00:29:31,580
+لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ
+
+372
+00:29:31,580 --> 00:29:32,860
+لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ
+
+373
+00:29:32,860 --> 00:29:34,660
+لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ
+
+374
+00:29:34,660 --> 00:29:34,980
+لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ
+
+375
+00:29:34,980 --> 00:29:40,660
+لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ لأ
+
+376
+00:29:40,660 --> 00:29:51,780
+لأ
+
+377
+00:29:52,220 --> 00:29:55,500
+الناس مابيدورش ع الشغل either because he or she
+
+378
+00:29:55,500 --> 00:29:59,820
+does not want a job or has giving up or given up
+
+379
+00:29:59,820 --> 00:30:03,700
+is not in the labor force مزح حالتكوا؟ بيدوروا ع
+
+380
+00:30:03,700 --> 00:30:09,240
+الشغل، مظبوط؟ انتوا 16 years old or more but you
+
+381
+00:30:09,240 --> 00:30:13,240
+don't search or look for a job so you are not in
+
+382
+00:30:13,240 --> 00:30:18,520
+the labor force okay but later on you are ان شاء
+
+383
+00:30:18,520 --> 00:30:21,600
+الله you will be active in the economy
+
+384
+00:30:25,610 --> 00:30:30,910
+لنبدأ بالتخصيص على عمولة العمولة العمولة العمولة
+
+385
+00:30:30,910 --> 00:30:33,910
+العمولة العمولة العمولة العمولة العمولة العمولة
+
+386
+00:30:33,910 --> 00:30:34,850
+العمولة العمولة العمولة العمولة العمولة العمولة
+
+387
+00:30:34,850 --> 00:30:35,770
+العمولة العمولة العمولة العمولة العمولة العمولة
+
+388
+00:30:35,770 --> 00:30:35,850
+العمولة العمولة العمولة العمولة العمولة العمولة
+
+389
+00:30:35,850 --> 00:30:38,230
+العمولة العمولة العمولة العمولة العمولة العمولة
+
+390
+00:30:38,230 --> 00:30:38,290
+العمولة العمولة العمولة العمولة العمولة العمولة
+
+391
+00:30:38,290 --> 00:30:39,670
+العمولة العمولة العمولة العمولة العمولة العمولة
+
+392
+00:30:39,670 --> 00:30:44,430
+العمولة العمولة العمولة العمولة العمولة
+
+393
+00:30:44,430 --> 00:30:53,660
+العمولة العمولة العنعم، المجتمع يكون عمره 16 سنة و
+
+394
+00:30:53,660 --> 00:31:00,260
+يجب أن يبحث عن عمل و .. حسنا؟ لذلك يحتوي .. أو
+
+395
+00:31:00,260 --> 00:31:04,440
+قوات العمل تحتوي على الناس الذين كانوا موظفين و
+
+396
+00:31:04,440 --> 00:31:13,040
+غير موظفين، صحيح؟ لذلك، في المجتمع، يوجد .. الناس
+
+397
+00:31:13,040 --> 00:31:20,600
+الذين كانوا عمرهم 16 سنة و أكتر ..بعضهم 1000 شخص
+
+398
+00:31:20,600 --> 00:31:25,160
+مستعمر
+
+399
+00:31:25,160 --> 00:31:28,860
+و700
+
+400
+00:31:28,860 --> 00:31:38,120
+مستعمر ومستعمر
+
+401
+00:31:38,120 --> 00:31:40,760
+ومستعمر ومستعمر
+
+402
+00:31:45,740 --> 00:31:50,800
+equals one thousand seven hundred employed plus
+
+403
+00:31:50,800 --> 00:31:57,620
+unemployed right what about the population العدد
+
+404
+00:31:57,620 --> 00:32:03,340
+السكان they are two parts labor force and not in
+
+405
+00:32:03,340 --> 00:32:06,100
+the labor force الناس ال population تبعناها ده هو
+
+406
+00:32:06,100 --> 00:32:09,260
+ناس في ال labor force اللي هم ال employed plus
+
+407
+00:32:09,260 --> 00:32:14,480
+unemployed وفي ناس not in the labor force تمام انت
+
+408
+00:32:14,480 --> 00:32:22,870
+و غيركunemployment rate equals what؟ ال unemployed
+
+409
+00:32:22,870 --> 00:32:27,610
+over ال labor force لهم ال employed plus
+
+410
+00:32:27,610 --> 00:32:32,330
+unemployed right طيب labor force participation
+
+411
+00:32:32,330 --> 00:32:35,090
+rate equals the labor force over the population
+
+412
+00:32:35,090 --> 00:32:43,310
+خلينا ناخد exercises على ال formulas هذه تمام؟ yes
+
+413
+00:32:45,330 --> 00:32:51,570
+Labor force is the total
+
+414
+00:32:51,570 --> 00:32:54,750
+number of labor force اللي هم ال unemployed plus
+
+415
+00:32:54,750 --> 00:32:58,570
+employed but the labor force participation rate
+
+416
+00:32:58,570 --> 00:33:03,310
+معدل المشارك في القوى العاملة اللي هم labor force
+
+417
+00:33:03,310 --> 00:33:07,630
+على ال population هم
+
+418
+00:33:07,630 --> 00:33:11,950
+جزء من القوى العاملة اللي مابشتغلوش تمام بس هم جزء
+
+419
+00:33:11,950 --> 00:33:15,440
+it's they are part of the labor forceلأن ال labor
+
+420
+00:33:15,440 --> 00:33:19,480
+force .. okay .. okay .. okay .. but طبعا .. طبعا
+
+421
+00:33:19,480 --> 00:33:21,600
+لأن هو جزء من القوى العاملة اللي دور على شغل و
+
+422
+00:33:21,600 --> 00:33:28,720
+مالاجهاش صح؟ طيب .. so let's go to take practical
+
+423
+00:33:28,720 --> 00:33:31,960
+exercises related to the .. to the calculation of
+
+424
+00:33:31,960 --> 00:33:35,160
+unemployment rate, labor force, labor force
+
+425
+00:33:35,160 --> 00:33:41,680
+participation rate and so onلذلك كما ترى لدينا
+
+426
+00:33:41,680 --> 00:33:47,360
+لبرا فورس موظف موظف ليس موظف المسؤال هو تخطيط رقم
+
+427
+00:33:47,360 --> 00:33:55,640
+الانتجار الانتجار موظف موظف ليس موظف ليس موظف ليس
+
+428
+00:33:55,640 --> 00:33:57,220
+موظف ليس موظف ليس موظف ليس موظف ليس موظف ليس موظف
+
+429
+00:33:57,220 --> 00:33:57,360
+ليس موظف ليس موظف ليس موظف ليس موظف ليس موظف ليس
+
+430
+00:33:57,360 --> 00:33:59,060
+ليس موظف ليس موظف ليس موظف ليس موظف ليس موظف ليس
+
+431
+00:33:59,060 --> 00:34:01,880
+موظف ليس موظف ليس موظف
+
+432
+00:34:04,030 --> 00:34:15,830
+أو 7.92 أو 5.6% سهل أعتقد أنها تغيير مباشرة
+
+433
+00:34:19,860 --> 00:34:25,000
+like unemployed and unemployed over labor force as
+
+434
+00:34:25,000 --> 00:34:28,780
+you like as you like you can write it directly
+
+435
+00:34:28,780 --> 00:34:35,540
+unemployed over the labor force that's it sorry
+
+436
+00:34:35,540 --> 00:34:40,320
+yes it should be given it should be considered yes
+
+437
+00:34:40,320 --> 00:34:44,020
+طيب what about the employment rate
+
+438
+00:34:49,560 --> 00:34:53,180
+ال employed من ال unemployed؟ ال employed على ال
+
+439
+00:34:53,180 --> 00:34:56,200
+labor force؟ exactly exactly employment rate
+
+440
+00:34:56,200 --> 00:34:59,520
+employment
+
+441
+00:34:59,520 --> 00:35:09,160
+rate employed over labor force okay times one
+
+442
+00:35:09,160 --> 00:35:09,420
+hundred
+
+443
+00:35:12,600 --> 00:35:19,400
+تمام it's a person طيب what else طيب as you see in
+
+444
+00:35:19,400 --> 00:35:24,080
+this example or this exercise we have the
+
+445
+00:35:24,080 --> 00:35:28,080
+following information about an economy which
+
+446
+00:35:28,080 --> 00:35:34,940
+includes the employed unemployed not in the labor
+
+447
+00:35:34,940 --> 00:35:39,060
+force the question is we have many questions
+
+448
+00:35:39,060 --> 00:35:50,270
+number oneاستخدام القوة العملية استخدام
+
+449
+00:35:50,270 --> 00:35:55,030
+القوة العملية الاستخدام القوة العملية الاستخدام
+
+450
+00:35:55,030 --> 00:36:00,270
+القوة العملية الاستخدام القوة العملية الاستخدام
+
+451
+00:36:00,270 --> 00:36:01,850
+القوة العملية الاستخدام القوة العملية الاستخدام
+
+452
+00:36:01,850 --> 00:36:03,010
+القوة العملية الاستخدام القوة العملية الاستخدام
+
+453
+00:36:03,010 --> 00:36:03,330
+القوة العملية الاستخدام القوة العملية الاستخدام
+
+454
+00:36:03,330 --> 00:36:05,450
+القوة العملية الاستخدام القوة العملية الاستخدام
+
+455
+00:36:05,450 --> 00:36:11,960
+القوة العملية الاستخدامالسؤال اتصل بالطابق اللي
+
+456
+00:36:11,960 --> 00:36:16,640
+يسمى unemployment rate equals what؟
+
+457
+00:36:16,640 --> 00:36:21,260
+بالضبط، unemployment rate
+
+458
+00:36:21,260 --> 00:36:29,140
+equals unemployed over labor force times one
+
+459
+00:36:29,140 --> 00:36:29,500
+hundred
+
+460
+00:36:34,040 --> 00:36:39,360
+استخدم الاسم الـ labor force participation rate
+
+461
+00:36:39,360 --> 00:36:43,340
+يتعرف على ميزة
+
+462
+00:36:43,340 --> 00:36:58,300
+ميزة ميزة ميزة ميزة ميزة ميزة ميزة ميزة
+
+463
+00:37:00,070 --> 00:37:06,870
+قيم المشاركة هو ماذا؟ قيم المشاركة على المجتمع
+
+464
+00:37:06,870 --> 00:37:10,510
+نحتاج
+
+465
+00:37:10,510 --> 00:37:17,070
+لنقلق المجتمع المجتمع مجتمع
+
+466
+00:37:17,070 --> 00:37:23,650
+مجتمع مجتمع بلس لا في مجتمع المجتمعلذلك في هذه
+
+467
+00:37:23,650 --> 00:37:26,410
+الحالة قيمة النار ليست موجودة في قيمة النار فهي
+
+468
+00:37:26,410 --> 00:37:29,290
+موجودة في قيمة النار فهي موجودة في قيمة النار فهي
+
+469
+00:37:29,290 --> 00:37:32,990
+موجودة في قيمة النار فهي موجودة في قيمة النار فهي
+
+470
+00:37:32,990 --> 00:37:33,930
+موجودة في قيمة النار فهي موجودة في قيمة النار فهي
+
+471
+00:37:33,930 --> 00:37:33,970
+موجودة في قيمة النار فهي موجودة في قيمة النار فهي
+
+472
+00:37:33,970 --> 00:37:35,330
+موجودة في قيمة النار فهي موجودة في قيمة النار فهي
+
+473
+00:37:35,330 --> 00:37:48,230
+موجودة في قيمة النار فهي موجودة في قيمة النار ف
+
+474
+00:37:54,020 --> 00:38:01,620
+القيمة العمليه 17000 دولار و 21000
+
+475
+00:38:01,620 --> 00:38:04,420
+دولار لأعمال العمليه 81000 دولار تقريبا تقريبا
+
+476
+00:38:04,420 --> 00:38:09,320
+تقريبا تقريبا
+
+477
+00:38:09,320 --> 00:38:15,080
+تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا
+
+478
+00:38:15,080 --> 00:38:15,100
+تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا
+
+479
+00:38:15,100 --> 00:38:17,440
+تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا تق
+
+480
+00:38:22,050 --> 00:38:26,590
+تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا
+
+481
+00:38:26,590 --> 00:38:30,610
+تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا
+
+482
+00:38:30,610 --> 00:38:30,650
+تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا
+
+483
+00:38:30,650 --> 00:38:45,490
+تقريبا تقريبا تقريب
+
+484
+00:38:45,640 --> 00:38:53,620
+المجتمع الكام 16 سنة من العمر والعمر والعمر والعمر
+
+485
+00:38:53,620 --> 00:38:55,080
+والعمر والعمر والعمر والعمر والعمر والعمر والعمر
+
+486
+00:38:55,080 --> 00:38:55,120
+والعمر والعمر والعمر والعمر والعمر والعمر والعمر
+
+487
+00:38:55,120 --> 00:38:55,860
+والعمر والعمر والعمر والعمر والعمر والعمر والعمر
+
+488
+00:38:55,860 --> 00:38:55,980
+والعمر والعمر والعمر والعمر والعمر والعمر والعمر
+
+489
+00:38:55,980 --> 00:38:56,220
+والعمر والعمر والعمر والعمر والعمر والعمر والعمر
+
+490
+00:38:56,220 --> 00:38:56,240
+والعمر والعمر والعمر والعمر والعمر والعمر والعمر
+
+491
+00:38:56,240 --> 00:38:57,840
+والعمر والعمر والعمر والعمر والعمر والعمر والعمر
+
+492
+00:38:57,840 --> 00:39:04,540
+والعمر والعمر والعمر والعمر وال
+
+493
+00:39:12,740 --> 00:39:18,440
+استخدموا المعرفة اللي بير فورس يعني ماذا؟ نستخدم
+
+494
+00:39:18,440 --> 00:39:24,600
+اللي بير فورس اللي بير فورس المشاركة اللي بير فورس
+
+495
+00:39:24,600 --> 00:39:27,800
+المشاركة اللي
+
+496
+00:39:27,800 --> 00:39:31,640
+بير فورس المشاركة اللي بير فورس المشاركة اللي بير
+
+497
+00:39:31,640 --> 00:39:33,280
+فورس المشاركة اللي بير فورس المشاركة اللي بير فورس
+
+498
+00:39:33,280 --> 00:39:35,340
+المشاركة اللي بير فورس المشاركة
+
+499
+00:39:38,900 --> 00:39:41,860
+لذلك .. نعم .. لذلك قيمة المشاركة لـ Labour Force
+
+500
+00:39:41,860 --> 00:39:52,620
+هي 0.75 مليون مليون مليون مليون مليون مليون
+
+501
+00:39:52,620 --> 00:39:52,740
+مليون مليون مليون مليون مليون مليون مليون مليون
+
+502
+00:39:52,740 --> 00:39:52,800
+مليون مليون مليون مليون مليون مليون مليون مليون
+
+503
+00:39:52,800 --> 00:39:53,820
+مليون مليون مليون مليون مليون مليون مليون مليون
+
+504
+00:39:53,820 --> 00:39:54,960
+مليون مليون مليون مليون مليون مليون مليون مليون
+
+505
+00:39:54,960 --> 00:39:58,880
+مليون مليون مليون
+
+506
+00:39:58,880 --> 00:40:01,960
+مليون
+
+507
+00:40:01,960 --> 00:40:05,180
+مليون
+
+508
+00:40:05,180 --> 00:40:06,460
+مليون مليون مليون مليون مليون مليون مليون مليون
+
+509
+00:40:06,460 --> 00:40:06,480
+مليون مليون مليون مليون مليون مليون مليون مليون
+
+510
+00:40:06,480 --> 00:40:08,450
+مليون مليون مليون مليون مليون مليون مليونصحيح؟ او
+
+511
+00:40:08,450 --> 00:40:13,270
+العاملين ماذا بعد ذلك؟ عندما نتحدث عن الطابق الوضع
+
+512
+00:40:13,270 --> 00:40:17,490
+الوضع الوضع الوضع
+
+513
+00:40:17,490 --> 00:40:20,610
+الوضع الوضع الوضع الوضع الوضع الوضع الوضع الوضع
+
+514
+00:40:20,610 --> 00:40:22,570
+الوضع الوضع الوضع الوضع الوضع الوضع الوضع الوضع
+
+515
+00:40:22,570 --> 00:40:23,010
+الوضع الوضع الوضع الوضع الوضع الوضع الوضع الوضع
+
+516
+00:40:23,010 --> 00:40:24,230
+الوضع الوضع الوضع الوضع الوضع الوضع الوضع الوضع
+
+517
+00:40:24,230 --> 00:40:24,290
+الوضع الوضع الوضع الوضع الوضع الوضع الوضع الوضع
+
+518
+00:40:24,290 --> 00:40:31,470
+الوضع الوضع الوضع الوضع الوضع
+
+519
+00:40:37,170 --> 00:40:42,430
+مينوس ماذا؟ أين رقم الموظفين هنا؟ هذا ليس
+
+520
+00:40:42,430 --> 00:40:51,670
+مُعروفًا. نستطيع أن نحصل عليه من ماذا؟ من
+
+521
+00:40:51,670 --> 00:40:57,150
+نسبة
+
+522
+00:40:57,150 --> 00:40:57,610
+الاستثمار.
+
+523
+00:41:00,190 --> 00:41:04,510
+من نسبة الاستثمار، كما تعلمين، نسبة الاستثمار
+
+524
+00:41:09,060 --> 00:41:14,040
+Equals what? Unemployed Over the labor force
+
+525
+00:41:14,040 --> 00:41:19,640
+Unemployment rate is given The labor force is
+
+526
+00:41:19,640 --> 00:41:23,320
+already calculated So we can derive the number of
+
+527
+00:41:23,320 --> 00:41:26,860
+unemployed Right? So unemployed The number of
+
+528
+00:41:26,860 --> 00:41:37,300
+unemployed Equals what? Unemployment rate Times
+
+529
+00:41:37,300 --> 00:41:38,280
+the labor force
+
+530
+00:41:43,680 --> 00:41:49,400
+So in this case unemployment equals or unemployed
+
+531
+00:41:49,400 --> 00:41:52,220
+equal the unemployment equals how much
+
+532
+00:41:52,220 --> 00:41:59,120
+unemployment rate 10% times the labor force the
+
+533
+00:41:59,120 --> 00:42:07,660
+labor force in this case equals what 150 15
+
+534
+00:42:07,660 --> 00:42:08,260
+مليون
+
+535
+00:42:10,910 --> 00:42:16,770
+صحيح؟ اذا ماهو ذلك؟ انها عدد المغامرين صحيح؟ ماهو
+
+536
+00:42:16,770 --> 00:42:22,810
+أخر؟ كتبوا عدد العميل، عدد الناس اللي مغامرين،
+
+537
+00:42:22,810 --> 00:42:29,830
+عميل يعني ماذا؟ بالضبط، قوة العميل minus عدد
+
+538
+00:42:29,830 --> 00:42:33,210
+المغامرين، أسف؟
+
+539
+00:42:35,640 --> 00:42:42,460
+نعم نعم لذلك دعونا نحصل على رقم الناس اللي موظف
+
+540
+00:42:42,460 --> 00:42:45,960
+موظف
+
+541
+00:42:45,960 --> 00:42:52,440
+موظف موظف
+
+542
+00:42:52,440 --> 00:42:55,200
+موظف موظف موظف موظف موظف موظف موظف موظف موظف موظف
+
+543
+00:42:55,200 --> 00:42:55,960
+موظف موظف موظف موظف موظف موظف موظف موظف موظف موظف
+
+544
+00:42:55,960 --> 00:42:56,560
+موظف موظف موظف موظف موظف موظف موظف موظف موظف موظف
+
+545
+00:42:56,560 --> 00:42:57,600
+موظف موظف موظف موظف موظف موظف موظف موظف موظف موظف
+
+546
+00:42:57,600 --> 00:43:04,080
+موظف موظف موظف موظف موظف موظف
+
+547
+00:43:04,080 --> 00:43:09,610
+مfifteen yes exactly one
+
+548
+00:43:09,610 --> 00:43:13,010
+hundred and thirty five this is what the number of
+
+549
+00:43:13,010 --> 00:43:19,290
+people who is employed what else yes exactly here
+
+550
+00:43:19,290 --> 00:43:24,070
+the unemployment rate okay
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/751lSdIbYlA.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/751lSdIbYlA.srt
new file mode 100644
index 0000000000000000000000000000000000000000..71e986be882a60beb6f4aed51909a1b5c36b16aa
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/751lSdIbYlA.srt
@@ -0,0 +1,1935 @@
+1
+00:00:21,970 --> 00:00:24,950
+Okay, بسم الله الرحمن الرحيم اليوم إن شاء الله
+
+2
+00:00:24,950 --> 00:00:32,830
+سنكمل الحلقة الثامنة، وسنقوم بالتحليق والتدخل،
+
+3
+00:00:32,830 --> 00:00:34,110
+والتدخل والتدخل والتدخل والتدخل والتدخل والتدخل والتدخل 
+
+4
+00:00:34,110 --> 00:00:38,390
+والتدخل والتدخل والتدخل والتدخل والتدخل والتدخل والتدخل
+
+5
+00:00:38,390 --> 00:00:38,590
+والتدخل والتدخل والتدخل والتدخل والتدخل والتدخل والتدخل
+
+6
+00:00:38,590 --> 00:00:38,610
+والتدخل والتدخل والتدخل والتدخل والتدخل والتدخل والتدخل
+
+7
+00:00:38,610 --> 00:00:42,930
+والتدخل والتدخل والتدخل والتدخل والتدخل والتدخل والتدخل
+
+8
+00:00:42,930 --> 00:00:50,050
+والتدخل، 
+
+9
+00:00:53,990 --> 00:00:56,370
+وهو الاستخدام الاستخدام الاستخدام الاستخدام
+
+10
+00:00:56,370 --> 00:00:57,350
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+11
+00:00:57,350 --> 00:01:00,430
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+12
+00:01:00,430 --> 00:01:04,090
+الاستخدام
+
+13
+00:01:04,090 --> 00:01:07,550
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+14
+00:01:07,550 --> 00:01:07,590
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+15
+00:01:07,590 --> 00:01:13,140
+الاستخدام الاستخدام الاستخدام الاستخدام الالتطور أو
+
+16
+00:01:13,140 --> 00:01:18,620
+تدفع الاقتصاد باستخدام اتفاق الاتفاق هذه الأدوات
+
+17
+00:01:18,620 --> 00:01:26,420
+تزيد عمليات الحكومة أو عمليات الحكومة أو تدفع 
+
+18
+00:01:26,420 --> 00:01:32,760
+السعر، لذلك عندما نتحدث عن اتفاق الاتفاق الاتفاق
+
+19
+00:01:32,760 --> 00:01:37,700
+الاتفاق الاتفاق
+
+20
+00:01:42,010 --> 00:01:49,430
+نحن نتكلم عن أزمة الحكومة أو أو أو أو أو أو أو
+
+21
+00:01:49,430 --> 00:01:50,150
+أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو
+
+22
+00:01:50,150 --> 00:01:50,290
+أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو
+
+23
+00:01:50,290 --> 00:01:53,050
+أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو
+
+24
+00:01:53,050 --> 00:01:53,690
+أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو
+
+25
+00:01:53,690 --> 00:01:54,870
+أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو أو
+
+26
+00:01:54,870 --> 00:01:58,150
+أو 
+
+27
+00:01:58,150 --> 00:02:01,310
+أو أو أو أو أو أو أو أو أو أو أو
+
+28
+00:02:06,240 --> 00:02:10,820
+سنبدأ عملية تحديث هذه السيطرة على السوق الخاص بنا
+
+29
+00:02:10,820 --> 00:02:12,580
+وبعدها السوق الخاص بنا على السوق الخاص بنا على
+
+30
+00:02:12,580 --> 00:02:14,240
+السوق الخاص بنا على السوق الخاص بنا على السوق
+
+31
+00:02:14,240 --> 00:02:16,300
+الخاص بنا على السوق الخاص بنا على السوق الخاص بنا
+
+32
+00:02:16,300 --> 00:02:19,420
+على السوق الخاص بنا على السوق الخاص بنا على السوق
+
+33
+00:02:19,420 --> 00:02:22,080
+الخاص بنا على السوق الخاص بنا على السوق الخاص بنا
+
+34
+00:02:22,080 --> 00:02:22,280
+على السوق الخاص بنا على السوق الخاص بنا على السوق
+
+35
+00:02:22,280 --> 00:02:22,920
+على السوق الخاص بنا على السوق الخاص بنا على السوق
+
+36
+00:02:22,920 --> 00:02:29,340
+الخاص بنا على السوق الخاص بنا على السوق 
+
+37
+00:02:29,340 --> 00:02:35,120
+الخاص بنا على السوق الخاص بنا على السوق الخاص بنا
+
+38
+00:02:35,970 --> 00:02:45,330
+وهنا لدينا الـ aggregate expenditure 1، الـ
+
+39
+00:02:45,330 --> 00:02:49,190
+equilibrium يحدث، أو الـ equilibrium الوحيد يحدث
+
+40
+00:02:49,190 --> 00:02:52,490
+عندما Y يقل aggregate expenditure، ومعرفة أن
+
+41
+00:02:52,490 --> 00:02:59,650
+aggregate expenditure 1 يقل C plus I plus G، صحيح؟
+
+42
+00:02:59,650 --> 00:03:05,570
+تمام؟ وهذا هو مقاومة الـ E1، هذا هو
+
+43
+00:03:12,520 --> 00:03:21,240
+هذا هو نتيجة 
+
+44
+00:03:21,240 --> 00:03:22,640
+التوازن
+
+45
+00:03:34,320 --> 00:03:38,400
+الحكومة تزوّد الناتج عن طريق
+
+46
+00:03:48,300 --> 00:03:51,640
+استخدام سياسة مالية توسعية، By increasing the
+
+47
+00:03:51,640 --> 00:03:55,920
+government spending and/or decreasing the taxes. So
+
+48
+00:03:55,920 --> 00:03:59,160
+what are the main consequences or effects or
+
+49
+00:03:59,160 --> 00:04:03,000
+impacts of this policy on the aggregate
+
+50
+00:04:03,000 --> 00:04:06,840
+expenditure? So increasing the government spending
+
+51
+00:04:06,840 --> 00:04:11,520
+leads to what? Increasing the aggregate
+
+52
+00:04:11,520 --> 00:04:15,680
+expenditure or aggregate demand, which leads to
+
+53
+00:04:15,680 --> 00:04:23,390
+what? ماذا هي التأثير التالف؟ بالضبط، 
+
+54
+00:04:23,390 --> 00:04:25,790
+تغيير الحركة العضلية التجاربية التجاربية التجاربية
+
+55
+00:04:25,790 --> 00:04:28,630
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+56
+00:04:28,630 --> 00:04:31,730
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+57
+00:04:31,730 --> 00:04:34,130
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+58
+00:04:34,130 --> 00:04:36,270
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+59
+00:04:36,270 --> 00:04:36,310
+التجاربية التجاربية التجاربية التجاربية التجاربية
+
+60
+00:04:36,310 --> 00:04:43,150
+التجاربية 
+
+61
+00:04:48,270 --> 00:04:51,210
+upward shifting of the aggregate expenditure، مش هي
+
+62
+00:04:51,210 --> 00:04:53,910
+اللي صار زيادة الإنفاق، زود ال aggregate
+
+63
+00:04:53,910 --> 00:04:57,450
+expenditure، وبتالي there is upward shifting of the
+
+64
+00:04:57,450 --> 00:05:00,610
+aggregate expenditure function، صح؟ صار في عندي هي
+
+65
+00:05:00,610 --> 00:05:03,570
+ال aggregate expenditure function، there is an 
+
+66
+00:05:03,570 --> 00:05:06,490
+upward shifting of the aggregate expenditure to
+
+67
+00:05:06,490 --> 00:05:11,750
+aggregate expenditure 2 equals C plus I plus G2
+
+68
+00:05:11,750 --> 00:05:17,440
+مظبوط؟ right? شو صار في الناتج في ال aggregate
+
+69
+00:05:17,440 --> 00:05:25,600
+output؟ this is E to exactly to Y2 so there is an 
+
+70
+00:05:25,600 --> 00:05:30,140
+increasing in the aggregate output from Y1 to Y2
+
+71
+00:05:30,140 --> 00:05:34,920
+right، صح ولا لأ؟ الزيادة في الناتج leads to
+
+72
+00:05:34,920 --> 00:05:38,580
+increasing to aggregate income، مظبوط؟ so let's
+
+73
+00:05:38,580 --> 00:05:41,840
+follow or complete the analysis here increasing of
+
+74
+00:05:41,840 --> 00:05:44,900
+Y means increasing of aggregate income
+
+75
+00:05:49,360 --> 00:05:53,360
+Increasing in income شو بيعمل في ال money demand؟
+
+76
+00:06:02,020 --> 00:06:06,380
+لذلك نحن لدينا تغيير كلمة صحيح للطريقة التي تتطلب
+
+77
+00:06:06,380 --> 00:06:10,400
+المال، إذا كنا نتكلم عن ماركت المال، فهناك تغيير 
+
+78
+00:06:10,400 --> 00:06:15,460
+كلمة صحيح للطريقة التي تتطلب المال، صح؟ إذا لو 
+
+79
+00:06:15,460 --> 00:06:19,000
+بدأ أجي لـ money demand curve أو ماركت المال،
+
+80
+00:06:19,000 --> 00:06:24,720
+نستطيع أن نرى ما 
+
+81
+00:06:24,720 --> 00:06:30,010
+هو العامة المالية في العامة المالية، لدينا مصادر 
+
+82
+00:06:30,010 --> 00:06:31,670
+المال والمصادر المالية، دماغ دماغ دماغ دماغ دماغ
+
+83
+00:06:31,670 --> 00:06:35,990
+دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ
+
+84
+00:06:35,990 --> 00:06:39,370
+دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ
+
+85
+00:06:39,370 --> 00:06:42,990
+دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ
+
+86
+00:06:42,990 --> 00:06:45,690
+دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ دماغ
+
+87
+00:06:45,690 --> 00:06:52,730
+دماغ دماغ دماغ 
+
+88
+00:06:52,730 --> 00:07:02,370
+DEM1 So this is QM and this is R And this is E1
+
+89
+00:07:02,370 --> 00:07:08,210
+Now the increasing in money demand leads to what? 
+
+90
+00:07:08,610 --> 00:07:11,950
+A rightward shifting exactly in the money demand
+
+91
+00:07:11,950 --> 00:07:14,690
+curve وبالتالي هي في عندي صار في انتقال في ال
+
+92
+00:07:14,690 --> 00:07:18,530
+money demand curve لوين؟ لليمين to money demand 2
+
+93
+00:07:20,870 --> 00:07:26,110
+صح ولا لأ؟ إذا... so we have a new interest rate
+
+94
+00:07:26,110 --> 00:07:34,070
+this is R2 increased مظبوط؟ طيب so the... let's...
+
+95
+00:07:34,070 --> 00:07:39,210
+so this is A2 so let's come back to our analysis
+
+96
+00:07:39,210 --> 00:07:42,250
+here, as you see the increasing in money demand
+
+97
+00:07:42,250 --> 00:07:46,890
+leads to what? Increasing in the interest rate. طب 
+
+98
+00:07:46,890 --> 00:07:49,950
+الزيادة في سعر الفائدة شو بتعمل في ال investment؟
+
+99
+00:07:50,270 --> 00:07:53,850
+بتنزلّوا، there is an inverse relationship بين ال
+
+100
+00:07:53,850 --> 00:07:56,630
+interest rate و ال investment. هيوة لو بده أرجع
+
+101
+00:07:56,630 --> 00:08:00,170
+لرسمها لجهة. So the increasing and the interest
+
+102
+00:08:00,170 --> 00:08:05,850
+rate leads to a decreasing in I or the planned
+
+103
+00:08:05,850 --> 00:08:12,650
+investment، مظبوط ولا لأ؟ لأنه أصلاً خليني أنغطي هذا 
+
+104
+00:08:12,650 --> 00:08:17,090
+هيك بس بيسكت 
+
+105
+00:08:18,600 --> 00:08:24,320
+Okay، رجع لك كمان شوية. Okay، so the increasing in 
+
+106
+00:08:24,320 --> 00:08:27,780
+the interest rate leads to a decreasing in the 
+
+107
+00:08:27,780 --> 00:08:30,280
+planned investment، مظبوط ولا لأ؟ طب ال planned
+
+108
+00:08:30,280 --> 00:08:33,560
+investment is part of aggregate expenditure، صح
+
+109
+00:08:33,560 --> 00:08:38,820
+exactly، so we have a decreasing in aggregate
+
+110
+00:08:38,820 --> 00:08:44,580
+expenditure، مظبوط؟ exactly، yes، with a smaller than 
+
+111
+00:08:44,580 --> 00:08:49,390
+the previous فيز طبعاً هذا ايه اكي صار في and with a 
+
+112
+00:08:49,390 --> 00:08:53,050
+small مصبوح 
+
+113
+00:08:53,050 --> 00:08:58,510
+إذا شو اللي صار؟ هل هيرجع ال aggregate expenditure
+
+114
+00:08:58,510 --> 00:09:05,930
+شو يصير؟ هيرجع ينزل مرة ثانية بس بالنسبة بسيطة. So 
+
+115
+00:09:05,930 --> 00:09:11,190
+here we have a downward shifting in the aggregate
+
+116
+00:09:11,190 --> 00:09:11,990
+expenditure
+
+117
+00:09:14,850 --> 00:09:19,470
+صح، هيو، جينا ليش؟ ل aggregate expenditure three، C 
+
+118
+00:09:19,470 --> 00:09:27,410
+plus I plus G two plus I two اللي نزلّها. So this is
+
+119
+00:09:27,410 --> 00:09:33,730
+I two، sorry، this is I two. So in the first case شو 
+
+120
+00:09:33,730 --> 00:09:39,370
+كان الوضع؟ كان في عندي upward shifting and then we
+
+121
+00:09:39,370 --> 00:09:45,400
+have a downward shifting with a small amount، صح؟ قال 
+
+122
+00:09:45,400 --> 00:09:53,740
+لها، this leads to what، the final، this is A3 شو
+
+123
+00:09:53,740 --> 00:09:58,280
+يعمل في النتيجة؟ exactly، so we have a small 
+
+124
+00:09:58,280 --> 00:10:02,400
+decreasing in the aggregate output. إذا هنا we have
+
+125
+00:10:02,400 --> 00:10:05,300
+a small decreasing in the aggregate expenditure
+
+126
+00:10:05,300 --> 00:10:12,860
+leads to a smaller decreasing in y، صح؟ حيومثبت ولا 
+
+127
+00:10:12,860 --> 00:10:19,800
+لأ؟ صح؟ شوفوا هذا ال small decreasing، إذا كانت 
+
+128
+00:10:19,800 --> 00:10:24,860
+الدولة أو ال government مخطط إنه يزيد الناتج from 
+
+129
+00:10:24,860 --> 00:10:30,700
+Y1 to Y2، يعني سبّز إنه بدي يزيد الناتج من 100
+
+130
+00:10:30,700 --> 00:10:36,460
+مليون لـ 300 مليون، unfortunately as a result of or
+
+131
+00:10:36,460 --> 00:10:42,560
+due to the crowding out، صار في عندي deduction or 
+
+132
+00:10:42,560 --> 00:10:47,740
+decreasing in the planned output، صار قول 280، يعني 
+
+133
+00:10:47,740 --> 00:10:51,960
+هم كانوا مخططين يزودوا الناتج من 100 لـ 300 لكن ما 
+
+134
+00:10:51,960 --> 00:10:57,620
+زادش لـ 300، نزل أو زاد من 100 لـ 280، هذا الفرق ال
+
+135
+00:10:57,620 --> 00:11:01,920
+decreasing بيسمّوه crowding out، crowding out، عارفين 
+
+136
+00:11:01,920 --> 00:11:03,700
+إيش يعني مزحمة؟
+
+137
+00:11:05,480 --> 00:11:09,980
+مزحمة للخلف بالنتج، يعني بمعنى أن النتج صار في عندي 
+
+138
+00:11:09,980 --> 00:11:14,560
+تّزاحمات نتيجة أن ال interest rate طلع أثر على ال
+
+139
+00:11:14,560 --> 00:11:18,680
+investment بالسلب وبالتالي صار في نزول في
+
+140
+00:11:18,680 --> 00:11:22,140
+aggregate output، ومن ثم هذا بيسمّوه crowding out. 
+
+141
+00:11:22,140 --> 00:11:26,820
+effect تمام؟ اه شباب؟ اذا if you would like to 
+
+142
+00:11:26,820 --> 00:11:32,540
+analyze or to analyze yes the effect of
+
+143
+00:11:35,230 --> 00:11:37,850
+interest or the relationship between interest rate
+
+144
+00:11:37,850 --> 00:11:41,430
+and the planned investment خلينا نعمل رسم هيك لل
+
+145
+00:11:41,430 --> 00:11:46,190
+interest rate و ل planned investment This is R I
+
+146
+00:11:46,190 --> 00:11:49,610
+and as you know that the relationship between R
+
+147
+00:11:49,610 --> 00:11:53,110
+and I is what？ Negative صح؟ أيوه
+
+148
+00:11:56,330 --> 00:12:01,030
+هذا I وهذا رقم الاستثمار المخطط مظبوط؟ طيب اين هو
+
+149
+00:12:01,030 --> 00:12:04,110
+الانترست الوحيد؟ وين كان الانترست الوحيد؟ هايه
+
+150
+00:12:04,110 --> 00:12:09,490
+ماشي مع رسمها هيك هاي الانترست الوحيد او الانترست 
+
+151
+00:12:09,490 --> 00:12:14,430
+الوحيد اللي هو ال R1 مظبوط؟ هايها هذا R1 وهذا E1
+
+152
+00:12:14,430 --> 00:12:19,470
+تطابق ما بين هذا وهذا؟ وهذا الانترست المخطط I1
+
+153
+00:12:22,360 --> 00:12:25,560
+when the money demand increased شو اللي صار ال
+
+154
+00:12:25,560 --> 00:12:30,720
+interest rate increased to
+
+155
+00:12:30,720 --> 00:12:38,440
+E2 this is R2 and I has declined to I2 نفس الشغل
+
+156
+00:12:38,440 --> 00:12:42,060
+اللي بنحكي فيه هذا هايو increasing in R leads to a
+
+157
+00:12:42,060 --> 00:12:45,720
+decreasing in I مظبوط then aggregate expenditure
+
+158
+00:12:45,720 --> 00:12:51,010
+declined and then Y declined تمام؟ وهذا الانزول هنا
+
+159
+00:12:51,010 --> 00:12:55,930
+اسمه crowding out تمام؟ مين مش فاهم عيدله؟ لأن
+
+160
+00:12:55,930 --> 00:13:01,950
+المحاضرة هدف الجزء منها في الامتحان انا
+
+161
+00:13:01,950 --> 00:13:06,270
+later on بحكيلك كيف بيجي السؤال بس بدي تفهم the
+
+162
+00:13:06,270 --> 00:13:08,970
+most important issue is to understand what I say
+
+163
+00:13:08,970 --> 00:13:13,330
+اه؟ طيب اذا let us summarize
+
+164
+00:13:27,080 --> 00:13:32,380
+الحكومة تستخدم سياسة مالية توسعية باستخدام استخدام
+
+165
+00:13:32,380 --> 00:13:32,820
+استخدام استخدام استخدام استخدام استخدام استخدام
+
+166
+00:13:32,820 --> 00:13:34,680
+استخدام استخدام استخدام استخدام استخدام استخدام
+
+167
+00:13:34,680 --> 00:13:34,760
+استخدام استخدام استخدام استخدام استخدام استخدام
+
+168
+00:13:34,760 --> 00:13:34,780
+استخدام استخدام استخدام استخدام استخدام استخدام
+
+169
+00:13:34,780 --> 00:13:43,440
+استخدام استخدام استخد
+
+170
+00:13:43,580 --> 00:13:46,280
+which leads to increasing aggregate output and
+
+171
+00:13:46,280 --> 00:13:50,040
+then increasing the aggregate income مظبوط؟ طيب
+
+172
+00:13:50,040 --> 00:13:53,840
+increasing the aggregate income leads to
+
+173
+00:13:53,840 --> 00:13:58,100
+increasing the money demand which leads to a
+
+174
+00:13:58,100 --> 00:14:01,460
+rightward shifting of the money demand curve صح؟
+
+175
+00:14:01,460 --> 00:14:07,770
+هي لأ و بدي أرجع شوية هيك Using an expansion of
+
+176
+00:14:07,770 --> 00:14:09,790
+fiscal policy means increasing the government
+
+177
+00:14:09,790 --> 00:14:12,130
+spending leads to increasing aggregate expenditure
+
+178
+00:14:12,130 --> 00:14:15,550
+from aggregate expenditure of the black line one
+
+179
+00:14:15,550 --> 00:14:19,610
+to the aggregate expenditure two So Y has
+
+180
+00:14:19,610 --> 00:14:23,470
+increased from Y one to Y two بصبو يعني if suppose
+
+181
+00:14:23,470 --> 00:14:29,850
+من مية لتلت مية طب بعد هيك The increasing in money
+
+182
+00:14:29,850 --> 00:14:34,750
+demand leads to increasing the interest rate صح؟ هي
+
+183
+00:14:34,750 --> 00:14:39,550
+ال interest rate طلع من R1 to R2 وهي ينبين عندى
+
+184
+00:14:39,550 --> 00:14:42,850
+هنا بال relationship between R and I او the
+
+185
+00:14:42,850 --> 00:14:46,830
+planned investment curve هي increasing في ال
+
+186
+00:14:46,830 --> 00:14:48,910
+interest rate طب عارفين احنا ال increasing في ال
+
+187
+00:14:48,910 --> 00:14:50,790
+interest rate هو ال cost of borrowing وبالتالي ال
+
+188
+00:14:50,790 --> 00:14:56,310
+investment بده يقل with a small amount اللي أثر
+
+189
+00:14:56,310 --> 00:14:59,830
+تلقائيا على ال aggregate expenditure ومن ثم ال
+
+190
+00:14:59,830 --> 00:15:04,610
+aggregate Y aggregate output or aggregate income
+
+191
+00:15:04,610 --> 00:15:09,250
+واللي رجع الناتج بدل ما كنا مخططين زوده من Y1 ل Y2
+
+192
+00:15:09,250 --> 00:15:16,850
+رح رجع شوية من Y2 ل Y3 هذا اسمه crowding out بس
+
+193
+00:15:16,850 --> 00:15:25,210
+طبعا طيب سؤال امتى بيكونش فيه تأثير لسعر الفائدة 
+
+194
+00:15:25,210 --> 00:15:29,110
+على الاستثمار على ال investment يعني لما بيزيد ال
+
+195
+00:15:29,110 --> 00:15:36,770
+interest rate ال investment مازيدش بيجلش اه
+
+196
+00:15:38,770 --> 00:15:42,610
+السؤال بيقول انه احنا بنقول انه ال crowding out او
+
+197
+00:15:42,610 --> 00:15:46,130
+مشكلة ال crowding out ظهرت وين لما .. لما ارتفع
+
+198
+00:15:46,130 --> 00:15:49,870
+سعر الفائدة نزل استثمار ومن ثم نزل الناتج صح؟ وهذا
+
+199
+00:15:49,870 --> 00:15:53,310
+الإشكالي اللي احنا مخطط ان ازود ال Y ال Inca ال
+
+200
+00:15:53,310 --> 00:15:56,930
+aggregate output من Y1 ل Y2 وبالتالي نتيجة انه
+
+201
+00:15:56,930 --> 00:16:01,790
+حساسية ال sensitivity لل investment لسعر الفائدة
+
+202
+00:16:01,790 --> 00:16:05,620
+هو اللي أثر على ان النتج يرجع لورا، مظبوط؟بس
+
+203
+00:16:05,620 --> 00:16:08,580
+السؤالي أنا خليني أسأل السؤال وبعدين أخد منكم
+
+204
+00:16:08,580 --> 00:16:14,680
+السؤال بيقول امتى جايك محمد هلأ السؤال بيقول انه
+
+205
+00:16:14,680 --> 00:16:18,300
+ممكن نرفع سعر الفائدة بس الاستثمار ماينزلش وقتاش
+
+206
+00:16:18,300 --> 00:16:22,500
+وبالتالي مافيش تأثير على ان ال income ال aggregate
+
+207
+00:16:22,500 --> 00:16:24,680
+expenditure ينزل yes تاني
+
+208
+00:16:30,040 --> 00:16:35,560
+لما يزيد نسبة ال government تمام بمقدار نسبة ال I
+
+209
+00:16:35,560 --> 00:16:40,920
+نزولها؟ لأ السؤال يه انه وقتهش انه ال interest
+
+210
+00:16:40,920 --> 00:16:44,760
+rate لما بيزيد ال investment ما بينزلش يسمحوا ..
+
+211
+00:16:44,760 --> 00:16:50,020
+exactly thank you very much indeed yes yes لما
+
+212
+00:16:50,020 --> 00:16:53,060
+بيكون ملحانة ال investment ال plant investment
+
+213
+00:16:53,060 --> 00:16:56,140
+vertical line ها يو خليه vertical line شو اللي
+
+214
+00:16:56,140 --> 00:17:02,110
+بيصير؟ ارفع ال interest rate ال investment مينزلش
+
+215
+00:17:02,110 --> 00:17:11,530
+خلّي ال investment curve vertical line خلّي عمودي
+
+216
+00:17:11,530 --> 00:17:19,810
+هيك exactly خلّي ال investment هيك vertical line
+
+217
+00:17:19,810 --> 00:17:25,850
+so this is R I وين ال interest rate الرئيسي؟ هيه
+
+218
+00:17:25,850 --> 00:17:31,810
+this is A1 وارتفع .. this is I1 R1 ارفع ال interest
+
+219
+00:17:31,810 --> 00:17:37,070
+rate زود ال interest rate to R2 ال investment I2
+
+220
+00:17:37,070 --> 00:17:43,030
+there is no decreasing in I عشان هيك لأ بتصير
+
+221
+00:17:43,030 --> 00:17:47,310
+بتصير عشان هيك بيكون مافيش crowding out في حالة
+
+222
+00:17:47,310 --> 00:17:53,170
+انه if the investment curve is vertical line معنى
+
+223
+00:17:53,170 --> 00:17:57,610
+الكلام انه الاستثمار مش حساس لسه على الفئدة صح؟
+
+224
+00:17:58,970 --> 00:18:02,670
+مظبوط؟ or the investment is not respond for the
+
+225
+00:18:02,670 --> 00:18:07,910
+interest rate مظبوط؟ مافيش استجابة للارتفاعات في
+
+226
+00:18:07,910 --> 00:18:11,750
+سعر الفدع تأثير على الاستثمار so in this case the
+
+227
+00:18:11,750 --> 00:18:16,270
+crowding out equals what？ zero exactly عشان هيك مش
+
+228
+00:18:16,270 --> 00:18:18,550
+هيرجع تاني ينزل aggregate expenditure
+
+229
+00:18:21,820 --> 00:18:24,420
+مفيش .. على .. it depends you have to analyze you
+
+230
+00:18:24,420 --> 00:18:27,460
+have to collect data او information about the
+
+231
+00:18:27,460 --> 00:18:31,000
+investment and interest rate و تشوف بالاخر احنا
+
+232
+00:18:31,000 --> 00:18:35,800
+بندرس cases على كيف بدي اخليه جايكلك كيف اخليه
+
+233
+00:18:35,800 --> 00:18:40,680
+thank you على سؤالك ازملكم بيسأل سؤال انه كيف بدي
+
+234
+00:18:40,680 --> 00:18:45,380
+اخلي ال investment او اللي هو ال investment مش
+
+235
+00:18:45,380 --> 00:18:50,010
+حساس او بدي ألغي تأثير سعر الفائدة عارفين شو بدي
+
+236
+00:18:50,010 --> 00:18:58,010
+أعمله؟ بدي أرجع بس للرسم هاي و أحل لك المشكلة this
+
+237
+00:18:58,010 --> 00:19:03,610
+is
+
+238
+00:19:03,610 --> 00:19:11,070
+I مظبوط and this is R and I تمام according to our
+
+239
+00:19:11,070 --> 00:19:13,570
+assumption this is E1
+
+240
+00:19:16,760 --> 00:19:27,480
+E2 R1 R2 I1 I2 في عنده increasing في ال R و
+
+241
+00:19:27,480 --> 00:19:35,500
+decreasing في ال I عشان ألغي تأثير to cancel the
+
+242
+00:19:35,500 --> 00:19:38,480
+effects of interest rate على سعر الفائد ده شو بعمل
+
+243
+00:19:38,480 --> 00:19:45,870
+الحل اللي قالك بسيطة الـ money supply كيف
+
+244
+00:19:45,870 --> 00:19:52,230
+تعمل تزوّد ال money supply خلاص اعمل rightward
+
+245
+00:19:52,230 --> 00:19:55,490
+shifting لـ money supply curve هيو جيبه هنا هيك
+
+246
+00:19:55,490 --> 00:19:56,690
+خلصنا ثبت
+
+247
+00:20:02,110 --> 00:20:06,990
+عشان ألغي تأثير ألغي crowding out زود ال money
+
+248
+00:20:06,990 --> 00:20:10,790
+supply شو صار ال interest rate نزل وبالتالي بطل
+
+249
+00:20:10,790 --> 00:20:14,370
+فيه التقى تأثير ال interest rate على ال investment
+
+250
+00:20:14,370 --> 00:20:21,420
+Yes عبدالله بالتأكيد، بالتأكيد، لكي نحل المشكلة من
+
+251
+00:20:21,420 --> 00:20:25,420
+المجتمع، المشكلة من المجتمع، لدينا أو الشركة
+
+252
+00:20:25,420 --> 00:20:32,440
+الأساسية لتحفة المال، أو لإستخدام منظمة تحفيزية،
+
+253
+00:20:32,440 --> 00:20:39,380
+نعم عبدالله Okay ماشي بس أنا the question is how
+
+254
+00:20:39,380 --> 00:20:43,560
+could we solve the crowding out effect يعني كيف
+
+255
+00:20:43,560 --> 00:20:48,700
+بدي ألغى تأثير هذا تأثير الارتفاع في سعر الفائدة؟
+
+256
+00:20:50,220 --> 00:20:56,820
+هذا الرد ع سؤالك وصلة تمام So as we mentioned that
+
+257
+00:20:56,820 --> 00:21:00,320
+using an expansionary fiscal policy as you see
+
+258
+00:21:00,320 --> 00:21:03,720
+leads to increasing aggregate expenditure then
+
+259
+00:21:03,720 --> 00:21:06,660
+aggregate output aggregate income increasing money
+
+260
+00:21:06,660 --> 00:21:09,480
+demand increasing interest rate decreasing I and
+
+261
+00:21:09,480 --> 00:21:13,740
+so on So the crowding out problem or the crowding
+
+262
+00:21:13,740 --> 00:21:19,610
+out ethic has been created when وين تولدت فكرة أو
+
+263
+00:21:19,610 --> 00:21:22,810
+مشكلة لـ crowding out when the government use an
+
+264
+00:21:22,810 --> 00:21:26,610
+expansionary fiscal policy صح؟ طيب، بدأ أروح
+
+265
+00:21:26,610 --> 00:21:32,930
+أستخدم let us use a contractionary fiscal policy
+
+266
+00:21:32,930 --> 00:21:36,750
+يعني أنا بدأ أستخدم إشي معاكس بمعنى إنه أنا بدأ
+
+267
+00:21:36,750 --> 00:21:42,110
+أستخدم contractionary fiscal policy by decreasing
+
+268
+00:21:42,110 --> 00:21:45,170
+the government spending and or increasing the
+
+269
+00:21:45,170 --> 00:21:48,870
+taxes خلينا نشوف وبدأ أشوف التأثير على ال three ..
+
+270
+00:21:48,870 --> 00:21:51,870
+على ال three .. ال analysis على ال three diagrams
+
+271
+00:21:51,870 --> 00:22:08,150
+هدول تمام؟ طيب So
+
+272
+00:22:08,150 --> 00:22:12,390
+let's use a contractionary fiscal policy
+
+273
+00:22:12,390 --> 00:22:16,090
+expansionary
+
+274
+00:22:28,960 --> 00:22:38,820
+سياسة مالية انكماشية by decreasing the government
+
+275
+00:22:38,820 --> 00:22:46,840
+spending or increasing the taxes يا بدنا ننزل انفاق
+
+276
+00:22:48,650 --> 00:22:51,690
+maybe ممكن يكون في علنا inflation عشان هيك
+
+277
+00:22:51,690 --> 00:22:55,010
+استخدموا سياسة مالية انكماشية بدهم يخفضوا ال
+
+278
+00:22:55,010 --> 00:22:59,030
+inflation عشان هيك راحوا يستخدموا سياسة مالية
+
+279
+00:22:59,030 --> 00:23:02,930
+انكماشية تمام؟ يمكن هذا ال reason هذا السبب او
+
+280
+00:23:02,930 --> 00:23:06,230
+اللي يعني اللي اللي خلهم يستخدموا contractionary
+
+281
+00:23:06,230 --> 00:23:09,070
+fiscal policy خلينا نشوف شو ال effects أو ال
+
+282
+00:23:09,070 --> 00:23:12,750
+impact of this policy on the goods market  والmoney 
+
+283
+00:23:12,750 --> 00:23:19,660
+market والاستثمار بشكل عام تمام؟ so as you 
+
+284
+00:23:19,660 --> 00:23:23,600
+we mentioned that the decrease in g leads to a
+
+285
+00:23:23,600 --> 00:23:26,660
+decrease in aggregate expenditure because g is
+
+286
+00:23:26,660 --> 00:23:29,040
+part of aggregate expenditure so a decrease in g
+
+287
+00:23:29,040 --> 00:23:31,620
+leads to a decrease in aggregate expenditure or
+
+288
+00:23:31,620 --> 00:23:37,660
+a decrease in aggregate demand  هديؤدي
+
+289
+00:23:37,660 --> 00:23:43,320
+لـ decrease in y aggregate output or
+
+290
+00:23:43,320 --> 00:23:46,930
+aggregate income مظبوط. الـ decrease في الـ
+
+291
+00:23:46,930 --> 00:23:50,810
+aggregate output أو الـ income شو معناه ده؟ leads
+
+292
+00:23:50,810 --> 00:23:56,450
+to a decrease of money demand صح؟
+
+293
+00:23:56,450 --> 00:23:59,890
+decrease في ال money demand we have a leftward
+
+294
+00:23:59,890 --> 00:24:04,770
+shifting of the money demand curve خليني أشوفها
+
+295
+00:24:04,770 --> 00:24:08,340
+أولا بدي أوضح  هذا طب هتقول بيؤدي إن ال interest
+
+296
+00:24:08,340 --> 00:24:12,500
+rate هينزل صح؟ so the leftward shifting of money
+
+297
+00:24:12,500 --> 00:24:16,820
+demand curve leads to a decrease in R which
+
+298
+00:24:16,820 --> 00:24:22,400
+means increase of I  و
+
+299
+00:24:22,400 --> 00:24:28,200
+اللي بيؤدي ل وين increase of
+
+300
+00:24:28,200 --> 00:24:31,220
+aggregate expenditure with a small amount
+
+301
+00:24:34,010 --> 00:24:41,690
+ومن ثم increase في ال Y with a small  هذا اسمه
+
+302
+00:24:41,690 --> 00:24:46,310
+crowding in شوفت العكس؟ يعني كوننا مخططين ننزل
+
+303
+00:24:46,310 --> 00:24:50,150
+الناتج يعني
+
+304
+00:24:50,150 --> 00:24:54,730
+من رقم لرقم، من 300 لـ 100، لكن نتيجة التزاحمات اللي
+
+305
+00:24:54,730 --> 00:24:59,330
+صارت أو تأثير الإيجابي لسعر الفائدة زود الناتج
+
+306
+00:24:59,330 --> 00:25:07,520
+بمقدار بسيط. لا بيبقى لها مستمرة بس بس you have to
+
+307
+00:25:07,520 --> 00:25:10,920
+understand the analysis يعني هذا اللي بدي إياك تفهمه
+
+308
+00:25:10,920 --> 00:25:15,480
+اللي بدك إذا بتمشي في السلسلة بتروح آه يعني إذا
+
+309
+00:25:15,480 --> 00:25:20,900
+بدي أمشي بالتحليل بروح على سوق ال labor market و
+
+310
+00:25:20,900 --> 00:25:23,600
+بروح على سوق ال bonds و هكذا بس أنا مش رايح
+
+311
+00:25:23,600 --> 00:25:28,810
+باتجاهات هذه يعني للتبسيط هي التحليل التبعي بس
+
+312
+00:25:28,810 --> 00:25:31,250
+تفهموا .. يعني it's far enough for you to
+
+313
+00:25:31,250 --> 00:25:34,570
+understand this يدرس advanced لطلاب التخصص في
+
+314
+00:25:34,570 --> 00:25:39,050
+الاقتصاد حتى يدرس في المصدر كمان مش بس .. let's
+
+315
+00:25:39,050 --> 00:25:42,330
+come back here to analyze the contractual fiscal
+
+316
+00:25:42,330 --> 00:25:48,230
+policy هذا
+
+317
+00:25:48,230 --> 00:25:53,470
+في ال goods market و .. and this is in the money
+
+318
+00:25:53,470 --> 00:26:05,160
+market and this is the investment curve نيجي هان y
+
+319
+00:26:05,160 --> 00:26:12,800
+aggregate expenditure one c
+
+320
+00:26:12,800 --> 00:26:18,600
+plus i plus g نقول one تمام؟ لأن أنا بدي أنزل ال g
+
+321
+00:26:18,600 --> 00:26:31,540
+and this is a one y one تمام؟ طيب الـ decrease في
+
+322
+00:26:31,540 --> 00:26:34,800
+الـ G أمل decrease في ال aggregate expenditure
+
+323
+00:26:34,800 --> 00:26:37,480
+so we have a downward shifting في ال aggregate
+
+324
+00:26:37,480 --> 00:26:41,160
+expenditure function صح؟ في عندي نزول في ال
+
+325
+00:26:41,160 --> 00:26:46,300
+aggregate expenditure function وليه صارت هيك؟ طبعا
+
+326
+00:26:46,300 --> 00:26:51,480
+هذا بيكون Parallel للتاني بشكل موازي So this is
+
+327
+00:26:51,480 --> 00:26:56,040
+aggregate expenditure to C plus I plus G2 اللي هو
+
+328
+00:26:56,040 --> 00:27:01,580
+فيه انخفاض في ال government spending تمام؟ طيب So
+
+329
+00:27:01,580 --> 00:27:06,960
+we have a new equilibrium which point E2 and this
+
+330
+00:27:06,960 --> 00:27:15,770
+is Y2 Suppose أنه كنا بدنا ننزل الناتج من 400 400$
+
+331
+00:27:15,770 --> 00:27:22,410
+ل 150$ هذا هو
+
+332
+00:27:22,410 --> 00:27:26,630
+المخطط التبعي إن أنا بدأت أنزل الناتج من 400$ ل 150$
+
+333
+00:27:26,630 --> 00:27:36,190
+طيب شو بصير لنذهب لـ money market هذا
+
+334
+00:27:36,190 --> 00:27:42,150
+ال money supply one money demand one and this is
+
+335
+00:27:42,150 --> 00:27:50,530
+the QMR أين المناطق المتساوية هنا هذا E1 وهذا R1
+
+336
+00:27:50,530 --> 00:27:54,730
+انتباه طيب ال decrease اللي صار في ال aggregate
+
+337
+00:27:54,730 --> 00:28:00,490
+expenditure شو بيعمل في الناتج نزل from Y1 to Y2 صح
+
+338
+00:28:00,490 --> 00:28:05,050
+ومن ثم ال aggregate income نزل هيّ this is
+
+339
+00:28:05,050 --> 00:28:10,450
+aggregate output or aggregate income ومن ثم ال money
+
+340
+00:28:10,450 --> 00:28:15,610
+demand decline صح؟ so there is a leftward shifting
+
+341
+00:28:15,610 --> 00:28:23,070
+in the money demand curve أيوة مدتو exactly شو صار
+
+342
+00:28:23,070 --> 00:28:28,110
+في ال interest rate نزل exactly so we have this is
+
+343
+00:28:28,110 --> 00:28:33,190
+a2 r2 we have a decrease in the interest rate
+
+344
+00:28:34,310 --> 00:28:45,670
+خلينا نرسم منحنى ال investment this is R I where
+
+345
+00:28:45,670 --> 00:28:53,210
+is the original interest rate هيّ وهيك this is E1
+
+346
+00:28:53,210 --> 00:28:59,330
+R1 we have a decrease in R and this is I1
+
+347
+00:29:02,430 --> 00:29:09,710
+we have a decrease in R to E2 R2 we have a
+
+348
+00:29:09,710 --> 00:29:17,030
+decrease in R and increase in I مظبوط؟
+
+349
+00:29:17,030 --> 00:29:21,570
+صح ولا لأ؟ هذا وين وداني؟ ال increase in I leads
+
+350
+00:29:21,570 --> 00:29:25,830
+to an increase in aggregate expenditure and then
+
+351
+00:29:25,830 --> 00:29:29,470
+Y with a small amount اللي هو ال crowding in إذا
+
+352
+00:29:29,470 --> 00:29:34,520
+خلينا نرسمه بال blue line هيو شفتوا قداش نزل
+
+353
+00:29:34,520 --> 00:29:37,720
+بالأول بدي أرجع أرفعه بحاجة بسيطة اللي هو ال
+
+354
+00:29:37,720 --> 00:29:43,520
+aggregate expenditure هنا هيو
+
+355
+00:29:43,520 --> 00:29:48,980
+there is a new equilibrium point صح هيّ suppose it
+
+356
+00:29:48,980 --> 00:29:58,890
+was E ثلاث this is Y3 شو معناها ده؟ Crowding in
+
+357
+00:29:58,890 --> 00:30:07,850
+exactly كنا مخططين ننزل الناتج من Y1 ل Y2 راح ننزل
+
+358
+00:30:07,850 --> 00:30:11,750
+بس من Y1 ل Y3 اللي هو المسافة هيّ، مظبوط ولا لأ؟
+
+359
+00:30:11,750 --> 00:30:16,150
+يعني لأنه رجع زاد الناتج شوية which called the
+
+360
+00:30:16,150 --> 00:30:22,810
+crowding in تمام؟ مين مش فاهم عيدله؟ صعب الأمور؟
+
+361
+00:30:23,550 --> 00:30:27,490
+يعني لو جيبناكم في الامتحان إنه اعملوا تحليل ال
+
+362
+00:30:27,490 --> 00:30:29,990
+analysis تبع ليه crowding out أو crowding in
+
+363
+00:30:29,990 --> 00:30:32,970
+بتقدروا تعمله by using expansion of fiscal policy
+
+364
+00:30:32,970 --> 00:30:35,090
+أو expansion of monetary policy أو اللي هو هذا
+
+365
+00:30:35,090 --> 00:30:39,650
+بتقدروا تعمله طيب تمام let's go to هل كده خلصنا من
+
+366
+00:30:39,650 --> 00:30:41,570
+تحليل السياسات ال
+
+367
+00:30:46,170 --> 00:30:50,670
+السياسة المالية اللي هي ال expansionary fiscal or
+
+368
+00:30:50,670 --> 00:30:54,510
+contractionary fiscal policy on the goods market
+
+369
+00:30:54,510 --> 00:30:57,510
+and the money market خلينا نروح على ال monetary
+
+370
+00:30:57,510 --> 00:31:01,670
+policy يعني suppose إننا نستخدم expansionary
+
+371
+00:31:01,670 --> 00:31:06,240
+monetary policy maybe by increasing the money
+
+372
+00:31:06,240 --> 00:31:11,060
+supply or something like this طيب إذا مين مش فاهم
+
+373
+00:31:11,060 --> 00:31:14,920
+طب شباب أعيد له جزئية التحليل المالي هذا ما فيش
+
+374
+00:31:14,920 --> 00:31:18,420
+مشكلة طيب إذا هداك أسهل إن شاء الله هيكون خليني
+
+375
+00:31:18,420 --> 00:31:26,100
+أروح ل ال monetary policy امسح امسح شباب okay
+
+376
+00:31:35,750 --> 00:31:38,530
+Expansionary fiscal policy ولا فيه ال contractionary
+
+377
+00:31:38,530 --> 00:31:44,430
+دائما ال expansionary بتولد مشكلة crowding out ال
+
+378
+00:31:44,430 --> 00:31:48,150
+contractionary بتولد أو بتظهر  اللي هو
+
+379
+00:31:48,150 --> 00:31:53,240
+crowding in تمام للفهم هذا لأنه هتظهر عندي كمان
+
+380
+00:31:53,240 --> 00:31:57,120
+شوية في ال expansionary monetary هيظهر فيها
+
+381
+00:31:57,120 --> 00:32:01,100
+crowding out دائما expansionary بظهر معاه crowding
+
+382
+00:32:01,100 --> 00:32:05,460
+out contractionary whether it was monetary أو
+
+383
+00:32:05,460 --> 00:32:10,080
+fiscal بيظهر عندي crowding in تمام خلينا نشوف so
+
+384
+00:32:10,080 --> 00:32:15,120
+let's go to the to use an expansionary monetary
+
+385
+00:32:15,120 --> 00:32:20,240
+policy expansionary رجعنا الصور بس شباب
+
+386
+00:32:29,080 --> 00:32:38,400
+Expansionary Monetary Policy تمام؟
+
+387
+00:32:38,400 --> 00:32:42,480
+طيب شو معنى Expansionary Monetary Policy؟ يعني
+
+388
+00:32:42,480 --> 00:32:45,580
+تزوّد المال الـ supply صح؟ طب كيف تزوّد المال الـ
+
+389
+00:32:45,580 --> 00:32:50,350
+supply؟ يا إما بدي أقلل الـ discount rate أو بدي
+
+390
+00:32:50,350 --> 00:32:54,290
+أقلل required reserve ratio أو شو بدي أعمل؟ بدي
+
+391
+00:32:54,290 --> 00:32:57,590
+أشتري bonds بظبط لأن إذا اشتريت bonds باعتلى الناس
+
+392
+00:32:57,590 --> 00:33:02,810
+فلوس وبتاع ال money supply بده يزيد صح؟ إذا I
+
+393
+00:33:02,810 --> 00:33:06,810
+have to use when I .. when the central bank use an
+
+394
+00:33:06,810 --> 00:33:10,250
+expansionary monetary policy this means increasing
+
+395
+00:33:10,250 --> 00:33:15,670
+the money supply by whether to decrease the 
+
+396
+00:33:15,670 --> 00:33:16,570
+discount rate
+
+397
+00:33:19,620 --> 00:33:23,320
+or decreasing the required reserve ratio or
+
+398
+00:33:23,320 --> 00:33:32,600
+purchasing bonds or buying bonds مظبوط؟
+
+399
+00:33:32,600 --> 00:33:34,720
+مش هي الثلاث أدوات اللي بيستخدمها ال central bank
+
+400
+00:33:34,720 --> 00:33:37,640
+أو ال federal reserve system عشان يزوّد ال money
+
+401
+00:33:37,640 --> 00:33:40,840
+supply طيب زيادة ال money supply بدأنا نبدأ بال
+
+402
+00:33:40,840 --> 00:33:46,100
+money supply هيّ this is the money market تمام؟ و
+
+403
+00:33:46,100 --> 00:33:46,460
+هذا
+
+404
+00:33:51,550 --> 00:33:55,710
+الـ investment line أو curve وهذا ال goods and
+
+405
+00:33:55,710 --> 00:34:00,870
+services market بال
+
+406
+00:34:00,870 --> 00:34:03,350
+money market بدأنا بإيش increase بال money
+
+407
+00:34:03,350 --> 00:34:09,510
+supply هيّ ال money supply vertical line MS1 and
+
+408
+00:34:09,510 --> 00:34:13,430
+this is the money demand curve one suppose إن وإن
+
+409
+00:34:13,430 --> 00:34:21,290
+هيك this is E1 R1 QM1
+
+410
+00:34:23,880 --> 00:34:30,660
+RQM بعدين أنا بشوف هنا وخليّ هذا this is the
+
+411
+00:34:30,660 --> 00:34:37,500
+investment curve ر I هذا
+
+412
+00:34:37,500 --> 00:34:42,580
+money market وهذا ال investment curve وهذا ال
+
+413
+00:34:42,580 --> 00:34:45,280
+goods market خليني أعمل ال original equilibrium
+
+414
+00:34:45,280 --> 00:34:49,680
+point Y
+
+415
+00:34:51,270 --> 00:35:02,030
+aggregate expenditure one c plus i plus g and this
+
+416
+00:35:02,030 --> 00:35:07,950
+is a one y
+
+417
+00:35:07,950 --> 00:35:15,960
+one y aggregate expenditure نيجي للتحليل التبعنا الـ
+
+418
+00:35:15,960 --> 00:35:17,700
+increase في ال money supply شو بيعمل في ال money
+
+419
+00:35:17,700 --> 00:35:21,240
+supply curve؟ exactly في عندنا rightward shifting
+
+420
+00:35:21,240 --> 00:35:24,320
+في مين؟ في ال money supply curve هي انقلو لليمين
+
+421
+00:35:24,320 --> 00:35:28,280
+ل
+
+422
+00:35:28,280 --> 00:35:34,100
+MS2 شو صار في ال interest rate؟ exactly so we have
+
+423
+00:35:34,100 --> 00:35:39,560
+a decreasing في ال interest rate to R2 this is A2
+
+424
+00:35:39,560 --> 00:35:45,240
+مابتقولي ال quantity of money increasedمظبوط؟ إذا
+
+425
+00:35:45,240 --> 00:35:48,020
+ال interest rate وين القديم؟ لو بدي أجي أعمل
+
+426
+00:35:48,020 --> 00:35:54,600
+القديم هيك هذا ال original interest rate صح؟ R1 E1
+
+427
+00:35:54,600 --> 00:36:01,000
+و هذا ال I1 مظبوط؟
+
+428
+00:36:01,000 --> 00:36:05,180
+ولا مش مظبوط؟ طيب ال rightward shifting في ال
+
+429
+00:36:05,180 --> 00:36:08,200
+money supply شو يعمل في ال interest rate؟ نزل ال
+
+430
+00:36:08,200 --> 00:36:11,280
+interest rate وبالتالي في عنده interest rate جديد
+
+431
+00:36:11,280 --> 00:36:12,140
+هنا هيك
+
+432
+00:36:15,070 --> 00:36:21,150
+E2 هيزيد ال investment exactly this is R2 وهذا I2
+
+433
+00:36:21,150 --> 00:36:26,450
+مظبوط؟ صح؟ طيب إذا خلّيني نمشي بالتحليل فوق هكذا
+
+434
+00:36:26,450 --> 00:36:31,910
+MS increased from MS1 to MS2 leads to what
+
+435
+00:36:31,910 --> 00:36:36,950
+increasing او decreasing in the interest rate طب
+
+436
+00:36:36,950 --> 00:36:38,650
+ال decreasing اللي صار في ال interest rate شو
+
+437
+00:36:38,650 --> 00:36:42,510
+بيعمل في ال I؟ بيزود ال I ومن ثم
+
+438
+00:36:45,270 --> 00:36:49,690
+بـ increasing في ال aggregate expenditure صح؟
+
+439
+00:36:49,690 --> 00:36:57,750
+مظبوط؟ هذا وين بوديني؟ increasing in Y صح؟ طيب
+
+440
+00:36:57,750 --> 00:37:04,330
+خليني نعمله هنا في ال goods market decreasing
+
+441
+00:37:04,330 --> 00:37:08,170
+في ال R increasing I increasing aggregate
+
+442
+00:37:08,170 --> 00:37:11,570
+expenditure و من ثم increasing Y so there is an
+
+443
+00:37:11,570 --> 00:37:13,530
+upward shifting في مين؟ في ال aggregate
+
+444
+00:37:13,530 --> 00:37:18,870
+expenditureهي بشكل بنحكي إذا هذا aggregate
+
+445
+00:37:18,870 --> 00:37:27,270
+expenditure to C plus I2 لأن I اللي اتغير plus G
+
+446
+00:37:27,270 --> 00:37:31,050
+صح
+
+447
+00:37:31,050 --> 00:37:33,810
+صح صح صح صح صح صح صح صح صح صح صح صح صح صح صح صح
+
+448
+00:37:33,810 --> 00:37:33,970
+صح صح صح صح صح صح صح صح صح صح صح صح صح صح صح صح
+
+449
+00:37:33,970 --> 00:37:35,890
+صح صح صح صح صح صح صح صح صح صح صح صح صح صح صح صح
+
+450
+00:37:35,890 --> 00:37:35,950
+صح صح صح صح صح صح صح صح صح صح صح صح صح صح صح صح
+
+451
+00:37:35,950 --> 00:37:36,030
+صح صح صح صح صح صح صح صح صح صح
+
+452
+00:37:40,880 --> 00:37:45,580
+مظبوط ولا لأ؟ صار في عندي upward shifting في ال
+
+453
+00:37:45,580 --> 00:37:48,900
+aggregate expenditure function صح؟ شو صار في
+
+454
+00:37:48,900 --> 00:37:54,880
+النتج؟ زياد من Y1 to Y2 طب شو اللي صار لما زياد ال
+
+455
+00:37:54,880 --> 00:38:00,500
+Y؟ أكثر على ال money demand مظبوط؟ زيادة ال Y ال
+
+456
+00:38:00,500 --> 00:38:03,520
+aggregate output او aggregate income بيزود ال
+
+457
+00:38:03,520 --> 00:38:07,980
+money demand طب زيادة ال money demand شو بتعمل في
+
+458
+00:38:07,980 --> 00:38:11,500
+ال interest rate؟بتزيده هى اعمل بصير فيه هنا end
+
+459
+00:38:11,500 --> 00:38:16,060
+ايش rightward shifting ل money demand curve هى اذا
+
+460
+00:38:16,060 --> 00:38:20,260
+فى الفيزي التانى صار فى عنا increasing فى ال money
+
+461
+00:38:20,260 --> 00:38:24,680
+demand هى وان ال money demand هى سببز انه اجى هيك
+
+462
+00:38:24,680 --> 00:38:28,420
+to money demand 2
+
+463
+00:38:34,840 --> 00:38:39,000
+وين الـ Intersection ما بين الـ MS2 و MD2؟ هايو،
+
+464
+00:38:39,000 --> 00:38:42,400
+الأحمر و الأزرق هذا We have a new interest rate
+
+465
+00:38:42,400 --> 00:38:47,780
+وبتلادى نزل سعر الفائدة from .. او sorry طلّع سعر
+
+466
+00:38:47,780 --> 00:38:56,060
+الفائدة from R2 to R3 مظبوط؟ ودّاني على E3 ومن ثم
+
+467
+00:38:56,060 --> 00:39:02,900
+ال interest rate زاد from R2 to R3 و ال investment
+
+468
+00:39:02,900 --> 00:39:11,860
+نزل from I2 to I3 صح؟ اذا هينهان هيك the increasing
+
+469
+00:39:11,860 --> 00:39:14,760
+in money demand increasing في ال money demand شو
+
+470
+00:39:14,760 --> 00:39:20,680
+يعمل increasing في ال R decreasing I decreasing
+
+471
+00:39:20,680 --> 00:39:25,080
+aggregate expenditure decreasing Y وهذا اسمه a
+
+472
+00:39:25,080 --> 00:39:29,700
+crowding ايش out هيو حيرجع شويه هيك
+
+473
+00:39:33,280 --> 00:39:38,060
+هذا الانزول البسيط اسمه crowding out لان انا مخطط
+
+474
+00:39:38,060 --> 00:39:46,180
+ازود الناتج من Y1 ل Y2 لكن حقيقة رجع شويه وصار Y3
+
+475
+00:39:46,180 --> 00:39:51,870
+اذا according to my planمخطط ليه ان ازالة عدد
+
+476
+00:39:51,870 --> 00:40:01,330
+الانترنت من Y1 ل Y2 بسبب ازالة الانترنت من Y1 ل Y2
+
+477
+00:40:01,330 --> 00:40:05,930
+بسبب ازالة انترنت من Y1 ل Y2 بسبب ازالة انترنت من
+
+478
+00:40:05,930 --> 00:40:13,930
+Y1 ل Y2 بسبب ازالة انترنت من Y1 ل Y2اللي بيظل ال
+
+479
+00:40:13,930 --> 00:40:17,270
+case الأخير اللي هو ال contractionary monetary
+
+480
+00:40:17,270 --> 00:40:21,130
+policy الحال المعاكسة بمعنى أنه هاي في عنده
+
+481
+00:40:21,130 --> 00:40:25,810
+contractionary monetary policy ال expansionary
+
+482
+00:40:25,810 --> 00:40:29,210
+monetary policy شوفنا ال crowding out ظهرت بدي
+
+483
+00:40:29,210 --> 00:40:33,310
+أشوف ال contractionary monetary policy بس وضحت
+
+484
+00:40:33,310 --> 00:40:36,150
+الصورة ولا مش مرة جاية بنكمل الجزئية 
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/751lSdIbYlA_raw.json b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/751lSdIbYlA_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..a28677ce1cde6438210da93d27bba6aff3da6038
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/751lSdIbYlA_raw.json
@@ -0,0 +1 @@
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التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية التجاربية الت", "tokens": [2304, 45636, 995, 39896, 16712, 10721, 12984, 13546, 16712, 6027, 5172, 22807, 20666, 11242, 3555, 9566, 12399, 6055, 17082, 1829, 13546, 21542, 31747, 3660, 18863, 11242, 1211, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 16712, 7435, 9640, 3555, 10632, 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"text": "هذا I وهذا رقم الاستثمار المخطط مظبوط؟ طيب اين هو الانترست الوحيد؟ وين كان الانترست الوحيد؟ هايه ماشي مع رسمها هيك هاي الانترست الوحيد او الانترست الوحيد اللي هو ال R1 مظبوط؟ هايها هذا R1 وهذا E1 تطابق ما بين هذا وهذا؟ وهذا الانترست المخطط I1", "tokens": [3224, 15730, 286, 37037, 15730, 12602, 4587, 2304, 42963, 14851, 12984, 2304, 9640, 9673, 9778, 9566, 9566, 3714, 19913, 3555, 2407, 9566, 22807, 23032, 1829, 3555, 1975, 9957, 31439, 2423, 7649, 2655, 2288, 14851, 2423, 2407, 5016, 25708, 22807, 4032, 9957, 25961, 2423, 7649, 2655, 2288, 14851, 2423, 2407, 5016, 25708, 22807, 8032, 47302, 3224, 3714, 33599, 1829, 20449, 12602, 38251, 11296, 39896, 4117, 8032, 47302, 2423, 7649, 2655, 2288, 14851, 2423, 2407, 5016, 25708, 1975, 2407, 2423, 7649, 2655, 2288, 14851, 2423, 2407, 5016, 25708, 13672, 1829, 31439, 2423, 497, 16, 3714, 19913, 3555, 2407, 9566, 22807, 8032, 995, 1829, 11296, 23758, 497, 16, 37037, 15730, 462, 16, 6055, 9566, 16758, 4587, 19446, 49374, 23758, 37037, 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the most important issue is to understand what I say اه؟ طيب اذا let us summarize", "tokens": [39237, 10943, 22807, 37037, 15730, 2423, 7649, 11622, 12610, 34105, 24525, 2304, 3224, 6401, 3584, 484, 46811, 10943, 22807, 3714, 9957, 37893, 6156, 995, 16095, 6225, 25708, 43761, 22807, 5296, 33456, 9673, 5016, 46958, 25720, 8032, 3215, 5172, 25724, 11622, 38207, 9154, 11296, 8978, 2423, 10943, 2655, 5016, 7649, 1975, 8315, 1780, 322, 4724, 5016, 4117, 1829, 23275, 9122, 33911, 4724, 1829, 7435, 1829, 21136, 33604, 6027, 4724, 3794, 4724, 16254, 6055, 5172, 16095, 264, 881, 1021, 2734, 307, 281, 1223, 437, 286, 584, 1975, 3224, 22807, 23032, 1829, 3555, 1975, 15730, 718, 505, 20858], "avg_logprob": -0.16748047278573117, "compression_ratio": 1.4504132231404958, "no_speech_prob": 0.0, "words": [{"start": 768.79, "end": 769.65, "word": "تمام؟", "probability": 0.7301432291666666}, {"start": 769.65, "end": 770.23, "word": " وهذا", "probability": 0.746337890625}, {"start": 770.23, "end": 770.77, 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"temperature": 1.0}, {"id": 77, "seek": 199657, "start": 1966.93, "end": 1996.57, "text": "يا اما بدى اقلل الـ discount rate او بدى اقلل required reserve ratio او شو بدى اعمل؟ بدى اشتري bonds بظبط لان اذا شريت bonds باعتلى الناس فلوس وبتاع ال money supply بده increase صح؟ اذا I have to use when I .. when the central bank use an expenditure monitor policy this means increasing the money supply by whether to decrease the discount rate", "tokens": [25528, 1975, 15042, 47525, 7578, 1975, 4587, 1211, 1211, 2423, 39184, 11635, 3314, 1975, 2407, 47525, 7578, 1975, 4587, 1211, 1211, 4739, 17824, 8509, 1975, 2407, 13412, 2407, 47525, 7578, 1975, 25957, 1211, 22807, 47525, 7578, 1975, 8592, 2655, 16572, 14713, 4724, 19913, 3555, 9566, 5296, 7649, 1975, 15730, 13412, 16572, 2655, 14713, 4724, 995, 34268, 23942, 2423, 8315, 3794, 6156, 1211, 41779, 46599, 2655, 45761, 2423, 1460, 5847, 47525, 3224, 3488, 20328, 5016, 22807, 1975, 15730, 286, 362, 281, 764, 562, 286, 4386, 562, 264, 5777, 3765, 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investment line أو curve وهذا ال goods and services market بال money market بدأنا بإيش increasing بال money supply هاي ال money supply vertical line MS1 and this is the money demand curve one suppose ان وان هيك this is E1 R1 QM1", "tokens": [6027, 39184, 6078, 1622, 34051, 7605, 37037, 15730, 2423, 10179, 293, 3328, 2142, 20666, 1460, 2142, 47525, 10721, 8315, 4724, 28814, 1829, 8592, 5662, 20666, 1460, 5847, 8032, 47302, 2423, 1460, 5847, 9429, 1622, 7395, 16, 293, 341, 307, 264, 1460, 4733, 7605, 472, 7297, 16472, 36764, 1863, 39896, 4117, 341, 307, 462, 16, 497, 16, 1249, 44, 16], "avg_logprob": -0.29583334624767305, "compression_ratio": 1.4728260869565217, "no_speech_prob": 0.0, "words": [{"start": 2031.55, "end": 2031.87, "word": "الـ", "probability": 0.59130859375}, {"start": 2031.87, "end": 2032.27, "word": " investment", "probability": 0.2425537109375}, {"start": 2032.27, "end": 2032.69, "word": " line", "probability": 0.9423828125}, {"start": 2032.69, "end": 2033.93, "word": " 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decreasing I decreasing aggregate expenditure decreasing Y وهذا اسمه a crowding ايش out هيو حيرجع شويه هيك", "tokens": [20579, 286, 17, 281, 286, 18, 20328, 5016, 22807, 1975, 15730, 8032, 9957, 3224, 7649, 39896, 4117, 264, 5662, 294, 1460, 4733, 5662, 8978, 2423, 1460, 4733, 13412, 2407, 7251, 25957, 1211, 5662, 8978, 2423, 497, 23223, 286, 23223, 26118, 40377, 23223, 398, 37037, 15730, 24525, 2304, 3224, 257, 6401, 3584, 1975, 1829, 8592, 484, 39896, 2407, 11331, 13546, 7435, 3615, 13412, 45865, 3224, 39896, 4117], "avg_logprob": -0.27495335287122585, "compression_ratio": 1.558011049723757, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 2344.9, "end": 2345.26, "word": "from", "probability": 0.443359375}, {"start": 2345.26, "end": 2345.8, "word": " I2", "probability": 0.78955078125}, {"start": 2345.8, "end": 2346.0, "word": " to", "probability": 0.90771484375}, {"start": 2346.0, "end": 2346.48, "word": " I3", "probability": 0.99267578125}, {"start": 2346.48, "end": 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2389.53, "end": 2411.57, "text": "مخطط ليه ان ازالة عدد الانترنت من Y1 ل Y2 بسبب ازالة الانترنت من Y1 ل Y2 بسبب ازالة انترنت من Y1 ل Y2 بسبب ازالة انترنت من Y1 ل Y2 بسبب ازالة انترنت من Y1 ل Y2", "tokens": [2304, 9778, 9566, 9566, 32239, 3224, 16472, 1975, 11622, 6027, 3660, 6225, 3215, 3215, 2423, 7649, 2655, 2288, 29399, 9154, 398, 16, 5296, 398, 17, 4724, 35457, 3555, 1975, 11622, 6027, 3660, 2423, 7649, 2655, 2288, 29399, 9154, 398, 16, 5296, 398, 17, 4724, 35457, 3555, 1975, 11622, 6027, 3660, 16472, 2655, 2288, 29399, 9154, 398, 16, 5296, 398, 17, 4724, 35457, 3555, 1975, 11622, 6027, 3660, 16472, 2655, 2288, 29399, 9154, 398, 16, 5296, 398, 17, 4724, 35457, 3555, 1975, 11622, 6027, 3660, 16472, 2655, 2288, 29399, 9154, 398, 16, 5296, 398, 17], "avg_logprob": -0.46480262593219157, "compression_ratio": 3.107142857142857, "no_speech_prob": 0.0, "words": [{"start": 2389.53, "end": 2390.09, "word": "مخطط", "probability": 0.409881591796875}, {"start": 2390.09, "end": 2390.51, "word": 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"end": 2405.93, "word": " ازالة", "probability": 0.9637451171875}, {"start": 2405.93, "end": 2405.93, "word": " انترنت", "probability": 0.9825439453125}, {"start": 2405.93, "end": 2405.93, "word": " من", "probability": 0.97705078125}, {"start": 2405.93, "end": 2405.93, "word": " Y1", "probability": 0.946044921875}, {"start": 2405.93, "end": 2406.23, "word": " ل", "probability": 0.98046875}, {"start": 2406.23, "end": 2408.15, "word": " Y2", "probability": 0.947998046875}, {"start": 2408.15, "end": 2409.25, "word": " بسبب", "probability": 0.7152506510416666}, {"start": 2409.25, "end": 2410.59, "word": " ازالة", "probability": 0.984619140625}, {"start": 2410.59, "end": 2411.01, "word": " انترنت", "probability": 0.9901123046875}, {"start": 2411.01, "end": 2411.03, "word": " من", "probability": 0.9853515625}, {"start": 2411.03, "end": 2411.37, "word": " Y1", "probability": 0.96435546875}, {"start": 2411.37, "end": 2411.37, "word": " ل", "probability": 0.98193359375}, {"start": 2411.37, "end": 2411.57, "word": " Y2", "probability": 0.9697265625}], "temperature": 1.0}, {"id": 93, "seek": 243615, "start": 2413.01, "end": 2436.15, "text": "اللي بيظل ال case الأخير اللي هو ال contractionary monetary policy الحال المعاكسة بمعنى أنه هاي في عنده contractionary monetary policy ال expansionary monetary policy شوفنا ال crowding out ظهرت بدي أشوف ال contractionary monetary policy بس وضحت الصورة ولا مش مرة جاية بنكمل الجزئية", "tokens": [6027, 20292, 4724, 1829, 19913, 1211, 2423, 1389, 16247, 9778, 13546, 13672, 1829, 31439, 2423, 37372, 822, 26388, 3897, 21542, 6027, 9673, 3615, 995, 4117, 3794, 3660, 4724, 2304, 3615, 1863, 7578, 14739, 3224, 8032, 47302, 8978, 43242, 3224, 37372, 822, 26388, 3897, 2423, 11260, 822, 26388, 3897, 13412, 38688, 8315, 2423, 6401, 3584, 484, 1357, 116, 3224, 43500, 4724, 16254, 5551, 8592, 38688, 2423, 37372, 822, 26388, 3897, 4724, 3794, 4032, 11242, 33753, 31767, 13063, 3660, 49429, 37893, 3714, 25720, 10874, 995, 10632, 44945, 24793, 1211, 25724, 11622, 19986, 10632], "avg_logprob": -0.23743206764692845, "compression_ratio": 1.8894230769230769, "no_speech_prob": 0.0, "words": [{"start": 2413.01, "end": 2413.33, "word": "اللي", "probability": 0.733154296875}, {"start": 2413.33, "end": 2413.79, "word": " بيظل", "probability": 0.784912109375}, {"start": 2413.79, "end": 2413.93, "word": " ال", "probability": 0.90966796875}, {"start": 2413.93, "end": 2414.21, "word": " case", "probability": 0.84423828125}, {"start": 2414.21, "end": 2414.69, "word": " الأخير", "probability": 0.8955078125}, {"start": 2414.69, "end": 2414.85, "word": " اللي", "probability": 0.895263671875}, {"start": 2414.85, "end": 2415.19, "word": " هو", "probability": 0.986328125}, {"start": 2415.19, "end": 2415.97, "word": " ال", "probability": 0.68310546875}, {"start": 2415.97, "end": 2416.89, "word": " contractionary", "probability": 0.7255859375}, {"start": 2416.89, "end": 2417.27, "word": " monetary", "probability": 0.892578125}, {"start": 2417.27, "end": 2417.75, "word": " policy", "probability": 0.93701171875}, {"start": 2417.75, "end": 2418.37, "word": " الحال", "probability": 0.847412109375}, {"start": 2418.37, "end": 2419.35, "word": " المعاكسة", "probability": 0.9019368489583334}, {"start": 2419.35, "end": 2419.73, "word": " بمعنى", "probability": 0.94140625}, {"start": 2419.73, "end": 2420.09, "word": " أنه", "probability": 0.620361328125}, {"start": 2420.09, "end": 2420.59, "word": " هاي", "probability": 0.6033935546875}, {"start": 2420.59, "end": 2420.69, "word": " في", "probability": 0.87060546875}, {"start": 2420.69, "end": 2421.13, "word": " عنده", "probability": 0.53314208984375}, {"start": 2421.13, "end": 2423.89, "word": " contractionary", "probability": 0.687744140625}, {"start": 2423.89, "end": 2424.11, "word": " monetary", "probability": 0.9013671875}, {"start": 2424.11, "end": 2424.63, "word": " policy", "probability": 0.9306640625}, {"start": 2424.63, "end": 2425.19, "word": " ال", "probability": 0.4990234375}, {"start": 2425.19, "end": 2425.81, "word": " expansionary", "probability": 0.946044921875}, {"start": 2425.81, "end": 2426.05, "word": " monetary", "probability": 0.94921875}, {"start": 2426.05, "end": 2426.37, "word": " policy", "probability": 0.9306640625}, {"start": 2426.37, "end": 2426.71, "word": " شوفنا", "probability": 0.8108723958333334}, {"start": 2426.71, "end": 2426.83, "word": " ال", "probability": 0.7783203125}, {"start": 2426.83, "end": 2427.35, "word": " crowding", "probability": 0.677490234375}, {"start": 2427.35, "end": 2427.79, "word": " out", "probability": 0.4560546875}, {"start": 2427.79, "end": 2428.71, "word": " ظهرت", "probability": 0.872802734375}, {"start": 2428.71, "end": 2429.21, "word": " بدي", "probability": 0.484375}, {"start": 2429.21, "end": 2429.63, "word": " أشوف", "probability": 0.94873046875}, {"start": 2429.63, "end": 2430.01, "word": " ال", "probability": 0.86376953125}, {"start": 2430.01, "end": 2431.03, "word": " contractionary", "probability": 0.980712890625}, {"start": 2431.03, "end": 2431.77, "word": " monetary", "probability": 0.96533203125}, {"start": 2431.77, "end": 2432.53, "word": " policy", "probability": 0.9189453125}, {"start": 2432.53, "end": 2433.05, "word": " بس", "probability": 0.958251953125}, {"start": 2433.05, "end": 2433.31, "word": " وضحت", "probability": 0.7240397135416666}, {"start": 2433.31, "end": 2433.75, "word": " الصورة", "probability": 0.9803059895833334}, {"start": 2433.75, "end": 2433.87, "word": " ولا", "probability": 0.85205078125}, {"start": 2433.87, "end": 2434.17, "word": " مش", "probability": 0.9072265625}, {"start": 2434.17, "end": 2434.93, "word": " مرة", "probability": 0.6361083984375}, {"start": 2434.93, "end": 2435.11, "word": " جاية", "probability": 0.774658203125}, {"start": 2435.11, "end": 2435.59, "word": " بنكمل", "probability": 0.9479166666666666}, {"start": 2435.59, "end": 2436.15, "word": " الجزئية", "probability": 0.7685546875}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2438.09525, "duration_after_vad": 2285.813124999989}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/8fHEZeTXGyo.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/8fHEZeTXGyo.srt
new file mode 100644
index 0000000000000000000000000000000000000000..61b78b66def370ad8328453ed053501efbeb1a69
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/8fHEZeTXGyo.srt
@@ -0,0 +1,1872 @@
+1
+00:00:20,860 --> 00:00:24,240
+Okay, بسم الله الرحمن الرحيم. Today, إن شاء الله, we
+
+2
+00:00:24,240 --> 00:00:28,560
+are going to complete our talk about the GDP 
+
+3
+00:00:28,560 --> 00:00:34,980
+calculation. كما تعلمين في السلسلة السابقة، اكتشفنا و
+
+4
+00:00:34,980 --> 00:00:41,000
+أشرحنا أننا لدينا إثنين من طرق لتخطيط GDP الوضع 
+
+5
+00:00:41,000 --> 00:00:48,080
+الدولي. هذه الطريقتان هما: الأولى التجارب، والثانية هي التجارب
+
+6
+00:00:48,080 --> 00:00:54,800
+الحيوانية. لذلك، اليوم دعونا نبدأ أو نبدأ بتجارب
+
+7
+00:00:54,800 --> 00:01:04,990
+التجارب لتخطيط GDP، كما ذكرنا عن طريق الاستخدام 
+
+8
+00:01:04,990 --> 00:01:06,450
+الاستخدام 
+
+9
+00:01:06,450 --> 00:01:07,670
+الاستخدام 
+
+10
+00:01:07,670 --> 00:01:09,570
+الاستخدام 
+
+11
+00:01:09,570 --> 00:01:11,410
+الاستخدام 
+
+12
+00:01:11,410 --> 00:01:11,610
+الاستخدام
+
+13
+00:01:11,610 --> 00:01:11,710
+الاستخدام 
+
+14
+00:01:11,710 --> 00:01:13,810
+الاستخدام 
+
+15
+00:01:13,810 --> 00:01:18,550
+الاستخدام 
+
+16
+00:01:18,550 --> 00:01:23,870
+الاستخدام 
+
+17
+00:01:23,870 --> 00:01:29,410
+الاستخدام
+
+18
+00:01:30,680 --> 00:01:36,280
+هو الاستثمار الوطني. 
+
+19
+00:01:36,280 --> 00:01:38,200
+ 
+
+20
+00:01:38,200 --> 00:01:38,680
+ 
+
+21
+00:01:38,680 --> 00:01:39,260
+ 
+
+22
+00:01:39,260 --> 00:01:46,600
+ 
+
+23
+00:01:46,600 --> 00:01:48,660
+ 
+
+24
+00:01:48,660 --> 00:01:59,240
+ 
+
+25
+00:02:01,320 --> 00:02:10,600
+الحكومة تدفع أو تدفع تجارب. 
+
+26
+00:02:10,600 --> 00:02:14,400
+ 
+
+27
+00:02:14,400 --> 00:02:14,440
+ 
+
+28
+00:02:14,440 --> 00:02:14,620
+ 
+
+29
+00:02:14,620 --> 00:02:15,120
+ 
+
+30
+00:02:15,120 --> 00:02:22,560
+ 
+
+31
+00:02:22,590 --> 00:02:30,410
+أخذ مهارة معينة أو مهارة معينة لتحسين GDP باستخدام 
+
+32
+00:02:30,410 --> 00:02:36,690
+تجارب الاستثمار أو استخدام هذه الصيغة، صحيح؟
+
+33
+00:02:36,690 --> 00:02:46,770
+حسنًا، كما ترى، الخصائص الهجومية هي C, I, ثم G و X 
+
+34
+00:02:46,770 --> 00:02:52,350
+مانوس MC. لذلك، دعونا ندفع الـ C أو الهجوم الشخصي
+
+35
+00:02:52,350 --> 00:02:55,570
+الإنفاق 
+
+36
+00:02:55,570 --> 00:03:00,370
+الاستهلاكي الشخصي، الذي هو الهيئة المستقبلية على 
+
+37
+00:03:00,370 --> 00:03:05,350
+المواد المستخدمة، استهلاك العائلة، اللي يحتوي على 
+
+38
+00:03:05,350 --> 00:03:13,260
+ثلاثة أشياء أهم أو ثلاثة أشياء أساسية: السلع المعمرة
+
+39
+00:03:13,260 --> 00:03:21,900
+هي السلع المعمرة التي تستخدمها لشراء أشياء 
+
+40
+00:03:21,900 --> 00:03:24,140
+مستقبلية ومساعدة.
+
+41
+00:03:24,140 --> 00:03:26,520
+ 
+
+42
+00:03:26,520 --> 00:03:29,160
+ 
+
+43
+00:03:29,160 --> 00:03:30,040
+ 
+
+44
+00:03:30,040 --> 00:03:34,880
+ 
+
+45
+00:03:34,880 --> 00:03:39,960
+ 
+
+46
+00:03:40,000 --> 00:03:44,860
+والأشياء المستدامة مثل الطعام والملابس وشيء مثل هذا. 
+
+47
+00:03:44,860 --> 00:03:49,940
+وماذا عن المساعدات؟ المساعدات مثل المدير والعائلة
+
+48
+00:03:49,940 --> 00:03:55,580
+تستخدم مالها أو تشتري مجموعات مختلفة مثل 
+
+49
+00:03:55,580 --> 00:04:00,680
+التليكوميكات والدراسات والصحة وما إلى ذلك، صح؟
+
+50
+00:04:00,680 --> 00:04:06,420
+الطوابق، بالضبط، نعم، لذا دعونا نشرح الـC أو
+
+51
+00:04:06,420 --> 00:04:12,910
+الإنتاج الشخصي. كما ترى، الإنتاج الشخصي يتضمن 
+
+52
+00:04:12,910 --> 00:04:15,790
+أشياء مستقبلية.
+
+53
+00:04:15,790 --> 00:04:17,410
+ 
+
+54
+00:04:17,410 --> 00:04:18,030
+ 
+
+55
+00:04:18,030 --> 00:04:19,790
+ 
+
+56
+00:04:19,790 --> 00:04:23,250
+ 
+
+57
+00:04:23,250 --> 00:04:27,430
+ 
+
+58
+00:04:27,430 --> 00:04:36,560
+أو أشياء مستقبلية such as the household 
+
+59
+00:04:36,560 --> 00:04:42,010
+spending on food and clothing. وماذا عن المساعدة؟
+
+60
+00:04:42,010 --> 00:04:46,650
+كما ترى أن المساعدة هي الأشياء التي لا تتعلق 
+
+61
+00:04:46,650 --> 00:04:54,870
+بالتصنيف أو الأشياء التجارية مثل تقضية المدرسة،
+
+62
+00:04:54,870 --> 00:04:59,710
+تقضية الدراسة، تقضية الكهرباء، تقضية 
+
+63
+00:04:59,710 --> 00:05:03,650
+transportation وما إلى ذلك، صحيح؟ لذلك، هذا هو 
+
+64
+00:05:03,650 --> 00:05:10,340
+المصطلح أو الأشياء الأساسية تقضية المساعدة في الاقتصاد
+
+65
+00:05:10,340 --> 00:05:18,140
+اللي هو جزء من GDP باستخدام تجارب الاستخدام. هل 
+
+66
+00:05:18,140 --> 00:05:23,240
+هناك مشكلة حتى الآن؟ حسنًا، الجزء الثاني من الـ
+
+67
+00:05:23,240 --> 00:05:29,180
+GDP هو الاستثمار العملي. دعنا نعود إلى المفهوم أو
+
+68
+00:05:29,180 --> 00:05:37,750
+مفهوم الاستثمار العملي. كما ترى، I هو الإنتاج 
+
+69
+00:05:37,750 --> 00:05:40,470
+الوطني. 
+
+70
+00:05:40,470 --> 00:05:42,530
+ 
+
+71
+00:05:42,530 --> 00:05:44,610
+ 
+
+72
+00:05:44,610 --> 00:05:45,890
+ 
+
+73
+00:05:45,890 --> 00:05:47,830
+ 
+
+74
+00:05:47,830 --> 00:05:51,450
+ 
+
+75
+00:05:51,450 --> 00:06:01,320
+ 
+لذلك، كما ترى، أنا أو الاستثمار
+
+76
+00:06:01,320 --> 00:06:07,620
+العظيم يتضمن إيه؟ يتضمن شركات وعائلات التي تستخدم 
+
+77
+00:06:07,620 --> 00:06:16,020
+الاستثمار مثل شراء أجهزة جديدة، شراء أجهزة مخصصة 
+
+78
+00:06:16,020 --> 00:06:21,390
+جديدة، inventory, it's called inventory، اللي هو 
+
+79
+00:06:21,390 --> 00:06:26,230
+المخزون تبع الـ .. الـ .. what else? building a new 
+
+80
+00:06:26,230 --> 00:06:32,430
+houses or it's called the .. yes, or buying a new
+
+81
+00:06:32,430 --> 00:06:35,570
+inputs or factors of production or like spare parts 
+
+82
+00:06:35,570 --> 00:06:40,210
+material. All of these things it's part of the
+
+83
+00:06:40,210 --> 00:06:46,870
+gross domestic investment, right? لنذهب إلى التفاصيل
+
+84
+00:06:46,870 --> 00:06:49,150
+المرتبطة بهذا الرمز.
+
+85
+00:06:53,870 --> 00:06:59,350
+لذلك، كما ترى، الإنبعاث يتعلق بشراء مال جديد، 
+
+86
+00:06:59,350 --> 00:07:05,050
+شراء رأس مال جديد، ما يسمى بالإنبعاث. كما ترى، 
+
+87
+00:07:05,050 --> 00:07:10,410
+الـ إنبعاث كامل بشركة خاصة يسمى الإنبعاث خاصة. 
+
+88
+00:07:10,410 --> 00:07:11,690
+ 
+
+89
+00:07:11,690 --> 00:07:12,270
+ 
+
+90
+00:07:12,270 --> 00:07:13,210
+ 
+
+91
+00:07:13,210 --> 00:07:13,970
+ 
+
+92
+00:07:13,970 --> 00:07:17,600
+أو تبني مبنى جديد و 
+
+93
+00:07:17,600 --> 00:07:20,300
+مصادر.
+
+94
+00:07:20,300 --> 00:07:22,340
+ 
+
+95
+00:07:22,340 --> 00:07:29,920
+ 
+
+96
+00:07:29,920 --> 00:07:33,300
+ 
+
+97
+00:07:33,300 --> 00:07:33,680
+ 
+
+98
+00:07:33,680 --> 00:07:41,120
+ 
+
+99
+00:07:41,120 --> 00:07:47,950
+هذا هو الإنتاج الكامل أو الإنتاج الكامل أو 
+
+100
+00:07:47,950 --> 00:07:54,750
+الإنتاج الكبير، وهذه هي المدى التي تم سوءها. لذا
+
+101
+00:07:54,750 --> 00:08:01,910
+لدينا inventory this or the X's اللي هو هذا يعني ال
+
+102
+00:08:01,910 --> 00:08:04,670
+difference between the total production and the
+
+103
+00:08:04,670 --> 00:08:10,270
+amount sold. إيش يسموه هذا ال X's أو خلينا نسميه 
+
+104
+00:08:10,270 --> 00:08:12,990
+هيك. what's the difference between the total 
+
+105
+00:08:12,990 --> 00:08:18,450
+production and sold؟ كده إيش؟ two hundred cars. هذا 
+
+106
+00:08:18,450 --> 00:08:24,720
+وإن بيروح؟ المخزون، inventory. Yes, exactly. على المتين
+
+107
+00:08:24,720 --> 00:08:27,260
+سيارة هدولة two hundred cars بنحطهم في المخزون.
+
+108
+00:08:27,260 --> 00:08:29,940
+وبالتالي صار في عندي a change in business
+
+109
+00:08:29,940 --> 00:08:32,920
+inventory. صار في تغير في المخزون، والتغير صار عندي 
+
+110
+00:08:32,920 --> 00:08:38,420
+شماله positive، صح؟ So, in this case, we have a 
+
+111
+00:08:38,420 --> 00:08:41,400
+positive change in business inventory. So, that
+
+112
+00:08:41,400 --> 00:08:44,840
+change in business inventory is part of the gross
+
+113
+00:08:44,840 --> 00:08:49,080
+domestic product، صح؟ لأن هو أصلاً جزء من الإنتاج 
+
+114
+00:08:50,480 --> 00:08:56,400
+مصبوط ولا لأ؟ sometimes or that's it. يعني، this is
+
+115
+00:08:56,400 --> 00:09:05,720
+the inventory change and business inventory. So, the
+
+116
+00:09:05,720 --> 00:09:12,200
+GDP includes the total production, not the total
+
+117
+00:09:12,200 --> 00:09:16,620
+sold، صح؟ So, the GDP
+
+118
+00:09:19,440 --> 00:09:27,800
+العامة، وليس العامة المجتمعة.
+
+119
+00:09:27,800 --> 00:09:32,000
+ 
+
+120
+00:09:32,000 --> 00:09:35,820
+الأخيرة، وليس العامة العامة المجتمعة.
+
+121
+00:09:35,820 --> 00:09:36,300
+ 
+
+122
+00:09:36,300 --> 00:09:37,560
+ 
+
+123
+00:09:37,560 --> 00:09:40,820
+ 
+
+124
+00:09:40,820 --> 00:09:45,980
+ 
+
+125
+00:09:47,890 --> 00:09:57,170
+Total Final Production Plus
+
+126
+00:09:57,170 --> 00:10:05,890
+GDP 
+
+127
+00:10:05,890 --> 00:10:08,790
+Equals Total Quantity Sold.
+
+128
+00:10:12,990 --> 00:10:14,670
+بالإضافة إلى تغيير المصادر العامة في المصادر.
+
+129
+00:10:14,670 --> 00:10:16,150
+ 
+
+130
+00:10:16,150 --> 00:10:17,010
+ 
+
+131
+00:10:17,010 --> 00:10:25,750
+ 
+
+132
+00:10:25,750 --> 00:10:28,330
+ 
+
+133
+00:10:28,330 --> 00:10:30,270
+ 
+
+134
+00:10:30,270 --> 00:10:31,470
+ 
+
+135
+00:10:31,470 --> 00:10:31,970
+ 
+
+136
+00:10:31,970 --> 00:10:32,030
+ 
+
+137
+00:10:32,030 --> 00:10:34,250
+ 
+
+138
+00:10:34,250 --> 00:10:41,890
+Yes, this is the total 
+
+139
+00:10:41,890 --> 00:10:49,930
+production. Right? So هذا بيشمل الـ final sold .. 
+
+140
+00:10:49,930 --> 00:10:53,170
+produced .. sorry .. the final goods which have 
+
+141
+00:10:53,170 --> 00:10:56,610
+been sold. Right? Plus the change in business 
+
+142
+00:10:56,610 --> 00:11:00,910
+inventory. هي اللي بيعناها زاد الـ change ..
+
+143
+00:11:00,910 --> 00:11:03,350
+التغير اللي صار هذا بيعطينا هو الـ total
+
+144
+00:11:03,350 --> 00:11:06,430
+production which is the gross domestic product or
+
+145
+00:11:06,430 --> 00:11:07,350
+the total production. Yes.
+
+146
+00:11:10,340 --> 00:11:18,740
+yes suppose that in this case we have 700
+
+147
+00:11:18,740 --> 00:11:24,780
+cars suppose
+
+148
+00:11:24,780 --> 00:11:28,420
+this quantity or this amount is the previous
+
+149
+00:11:28,420 --> 00:11:34,480
+inventory right and we produced 1000 cars in this
+
+150
+00:11:34,480 --> 00:11:40,730
+year عندي أنا في المخزون أصلا سبعمية سيارة وراح 
+
+151
+00:11:40,730 --> 00:11:46,750
+ننتج one thousand cars in this year and we
+
+152
+00:11:46,750 --> 00:11:53,970
+found that the demand in this year is one thousand
+
+153
+00:11:53,970 --> 00:11:57,330
+.. this is the demand or they sold .. they
+
+154
+00:11:57,330 --> 00:12:05,400
+quantized sold one thousand four hundred لذلك في
+
+155
+00:12:05,400 --> 00:12:09,000
+هذه الحالة هناك تغيير نقلي في مصادر المصادر كم؟
+
+156
+00:12:09,000 --> 00:12:13,540
+400 لذلك في هذه الحالة لدينا تغيير نقلي في مصادر 
+
+157
+00:12:13,540 --> 00:12:20,420
+المصادر ب 400 لذلك كما ترى أكبر نوع مصادر المصادر
+
+158
+00:12:20,420 --> 00:12:24,060
+في هذه الحالة أو أكثر مصادر مصادر في هذه السنة يقل
+
+159
+00:12:24,060 --> 00:12:30,630
+1400 أكثر مصادر مصادر مصادر مصادر أعطاني إنتاج
+
+160
+00:12:30,630 --> 00:12:35,750
+السنة صح؟ So as you see the GDP or the total
+
+161
+00:12:35,750 --> 00:12:42,200
+production equals the total quantity sold plus the
+
+162
+00:12:42,200 --> 00:12:45,540
+change in business inventory which might be
+
+163
+00:12:45,540 --> 00:12:50,840
+positive or sometimes negative right so yes
+
+164
+00:12:50,840 --> 00:12:55,460
+exactly so in this case sold a quant sold plus the
+
+165
+00:12:55,460 --> 00:12:57,640
+change in business inventory which might be
+
+166
+00:12:57,640 --> 00:13:02,180
+negative and sometimes it would be positive right
+
+167
+00:13:02,180 --> 00:13:06,640
+so let's come back to the definitions and the
+
+168
+00:13:06,640 --> 00:13:14,260
+explanation for the terms okay هو واضح أو أنك تحتاج
+
+169
+00:13:14,260 --> 00:13:26,400
+شيء أكثر؟ كما
+
+170
+00:13:26,400 --> 00:13:31,840
+ذكرنا أن الاستثمار 
+
+171
+00:13:31,840 --> 00:13:36,300
+الكبير يتضمن الاستثمار الكبير يتضمن
+
+172
+00:13:39,920 --> 00:13:44,600
+construction or residential investment, non
+
+173
+00:13:44,600 --> 00:13:48,780
+-residential investment and the change in business
+
+174
+00:13:48,780 --> 00:13:50,080
+inventories
+
+175
+00:14:00,260 --> 00:14:05,400
+الاستثمار عندما نتحدث عن الاستثمار في الـ GDP نحن 
+
+176
+00:14:05,400 --> 00:14:09,280
+نتحدث عن الاستثمار المشروع وليس الاستثمار المجلد 
+
+177
+00:14:09,280 --> 00:14:14,020
+لذلك الاستثمار المشروع الاستثمار
+
+178
+00:14:14,020 --> 00:14:20,460
+اللي هو I يحتوي 
+
+179
+00:14:20,460 --> 00:14:23,900
+على استثمار غير مستقل
+
+180
+00:14:30,600 --> 00:14:35,680
+plus residential investment
+
+181
+00:14:35,680 --> 00:14:45,890
+plus the change in inventory خليني أوضحهم الـ non
+
+182
+00:14:45,890 --> 00:14:50,010
+-residential investment اللي هو الاستثمار في أشياء
+
+183
+00:14:50,010 --> 00:14:54,810
+غير المساكن، غير المباني وهذا related to مين؟ to
+
+184
+00:14:54,810 --> 00:15:00,190
+the firms when they buy equipment, machines and so
+
+185
+00:15:00,190 --> 00:15:04,290
+on القطاع ال .. ال firms هذا بيشتري ال business
+
+186
+00:15:04,290 --> 00:15:07,470
+بيشتري equipment، this is part of investment it's
+
+187
+00:15:07,470 --> 00:15:12,170
+called non-residential investment يسموه قطاع اللي
+
+188
+00:15:12,170 --> 00:15:15,590
+هو الاستثمار في إيش غير المساكن طب في إيش اسمه 
+
+189
+00:15:15,590 --> 00:15:19,070
+residential investment residential investment اللي 
+
+190
+00:15:19,070 --> 00:15:23,350
+هو استثمار the investment of the households and
+
+191
+00:15:23,350 --> 00:15:27,330
+the investment of firms or the business sector in
+
+192
+00:15:27,330 --> 00:15:32,250
+residential or construction so suppose you are as
+
+193
+00:15:32,250 --> 00:15:38,410
+a household sector decided to build a new houses in
+
+194
+00:15:38,410 --> 00:15:41,550
+this case it's part .. it's called the residential
+
+195
+00:15:41,550 --> 00:15:46,770
+investment إذا ال firms .. if the firms produces
+
+196
+00:15:46,770 --> 00:15:50,150
+or build also new houses for investment it's
+
+197
+00:15:50,150 --> 00:15:53,190
+called .. it's part of the residential investment
+
+198
+00:15:53,190 --> 00:15:58,260
+تمام؟ والخير الأخير لـ Gross Investment هو
+
+199
+00:15:58,260 --> 00:16:02,240
+التغيير في الـ Business Inventory اللي تم تفضيله
+
+200
+00:16:02,240 --> 00:16:05,940
+أو تتكلم عنه الآن كما ترى فاهمينه التغيير في
+
+201
+00:16:05,940 --> 00:16:10,000
+Business Inventory؟ هل هو صحيح؟ لذلك دعونا نذهب
+
+202
+00:16:10,000 --> 00:16:13,240
+إلى التفريق بين الـ Residential و الـ Non
+
+203
+00:16:13,240 --> 00:16:17,560
+-residential و التغيير في Business Inventory كما
+
+204
+00:16:17,560 --> 00:16:23,290
+ترى التغيير في الـ Non-residential هو includes
+
+205
+00:16:23,290 --> 00:16:27,550
+expenditures by the firms for machines, tools,
+
+206
+00:16:27,850 --> 00:16:31,950
+plants and so on what about the residential
+
+207
+00:16:31,950 --> 00:16:35,590
+investment residential investment includes
+
+208
+00:16:35,590 --> 00:16:39,930
+expenditures by who's by the households and the
+
+209
+00:16:39,930 --> 00:16:45,790
+firms on a new houses and apartment buildings تمام
+
+210
+00:16:46,610 --> 00:16:50,790
+والخير الأخير هو التغيير في الانفجار الخاص بالعمل
+
+211
+00:16:50,790 --> 00:16:54,630
+أو التغيير في الانفجار كما ذكرنا في المثال السابق
+
+212
+00:16:54,630 --> 00:17:00,350
+والأخير يقوم بتغيير قيمة من أي شركة انفجارها 
+
+213
+00:17:00,350 --> 00:17:05,190
+تغييرها في مرحلة محددة كم تتخيل مخزوننا من مرحلة
+
+214
+00:17:05,190 --> 00:17:12,230
+لمرحلة انتجنا وبيعنا وهكذا فالانفجارات تحتوي على
+
+215
+00:17:12,230 --> 00:17:19,740
+شو الانفجارات تشمل مواد عادية ومواد متوسطة ومواد 
+
+216
+00:17:19,740 --> 00:17:23,850
+مخصصة للمواطنين ومواد عادية ومواد متوسطة اللي
+
+217
+00:17:23,850 --> 00:17:29,830
+suppose انه في firm عنده they imported أو
+
+218
+00:17:29,830 --> 00:17:35,930
+purchased أو imported raw material and spare parts
+
+219
+00:17:35,930 --> 00:17:38,070
+for the machines in order for .. for maintenance
+
+220
+00:17:38,070 --> 00:17:41,290
+purposes it's called .. it's part of the changing
+
+221
+00:17:41,290 --> 00:17:44,610
+business inventory or it's part of .. yes because
+
+222
+00:17:44,610 --> 00:17:48,570
+it will be used it's a .. it has been produced now
+
+223
+00:17:48,570 --> 00:17:54,700
+and it will be used later on صح؟ واحد جايب قطع غيار
+
+224
+00:17:54,700 --> 00:17:58,200
+من برا للماكينة الموجود عنده قاعد بينتج فيها هذا
+
+225
+00:17:58,200 --> 00:18:01,520
+إيش بده يساوي بيحط القطع الغيار عنده في المخزن لما 
+
+226
+00:18:01,520 --> 00:18:05,140
+بنحتاجها للماكينة لصيانة بده يستخدمها وبتالي هذا
+
+227
+00:18:05,140 --> 00:18:09,140
+أصلاً it's part of it's called it's part of the
+
+228
+00:18:09,140 --> 00:18:11,920
+change in business inventory right okay
+
+229
+00:18:15,530 --> 00:18:21,390
+لذلك يجب أن نذكر أن الـ GDP ليس قيمة الأسعار
+
+230
+00:18:21,390 --> 00:18:25,470
+الأكثر من الأسعار أكثر من الأسعار أكثر من
+
+231
+00:18:25,470 --> 00:18:27,470
+الأسعار أكثر من الأسعار أكثر من الأسعار أكثر 
+
+232
+00:18:27,470 --> 00:18:28,830
+من الأسعار أكثر من الأسعار أكثر من الأسعار
+
+233
+00:18:28,830 --> 00:18:28,850
+أكثر من الأسعار أكثر من الأسعار أكثر من 
+
+234
+00:18:28,850 --> 00:18:29,070
+الأسعار أكثر من الأسعار أكثر من الأسعار أكثر
+
+235
+00:18:29,070 --> 00:18:29,770
+من الأسعار أكثر من الأسعار أكثر من الأسعار
+
+236
+00:18:29,770 --> 00:18:30,370
+أكثر من الأسعار أكثر من الأسعار أكثر من 
+
+237
+00:18:30,370 --> 00:18:32,950
+الأسعار أكثر من الأسعار أكثر من الأسعار أكثر 
+
+238
+00:18:32,950 --> 00:18:37,210
+من الأسعار  أكثرالسائق والتغيير في المصادر العامة،
+
+239
+00:18:37,210 --> 00:18:43,510
+صحيح؟ صحيح؟ لذلك عندما نتكلم عن GDP، لسنا نتكلم عن 
+
+240
+00:18:43,510 --> 00:18:48,670
+قيم السوق لسائقنا، لكننا نتكلم عن قيم السوق كمية 
+
+241
+00:18:48,670 --> 00:18:56,150
+المصادر أو الأشياء الأخيرة، صحيح؟ لذلك كما ترى
+
+242
+00:18:58,610 --> 00:19:01,390
+العلاقة بين تجارب المصادر والتجارب المصادرة
+
+243
+00:19:01,390 --> 00:19:01,870
+والتجارب المصادرة والتجارب المصادرة والتجارب
+
+244
+00:19:01,870 --> 00:19:03,830
+المصادرة والتجارب المصادرة والتجارب المصادرة
+
+245
+00:19:03,830 --> 00:19:07,450
+والتجارب المصادرة والتجارب المصادرة والتجارب
+
+246
+00:19:07,450 --> 00:19:11,230
+المصادرة والتجارب المصادرة والتجارب المصادرة
+
+247
+00:19:11,230 --> 00:19:13,650
+والتجارب المصادرة والتجارب المصادرة والتجارب
+
+248
+00:19:13,650 --> 00:19:13,690
+والتجارب المصادرة والتجارب المصادرة والتجارب
+
+249
+00:19:13,690 --> 00:19:15,870
+المصادرة والتجارب المصادرة والتجارب المصادرة
+
+250
+00:19:15,870 --> 00:19:20,850
+والتجارب المصادرة والتجارب المصادرة والتجار
+
+251
+00:19:23,180 --> 00:19:28,880
+Okay so I will talk or discuss everything slowly
+
+252
+00:19:28,880 --> 00:19:37,500
+slowly إن شاء الله don't worry okay okay So
+
+253
+00:19:37,500 --> 00:19:43,060
+let's go to the gross investment a gross
+
+254
+00:19:43,060 --> 00:19:48,330
+investment is the total value of all in newly
+
+255
+00:19:48,330 --> 00:19:52,710
+produced capital goods like plant, equipment,
+
+256
+00:19:52,990 --> 00:19:56,690
+housing and inventory produced in a given period
+
+257
+00:19:56,690 --> 00:20:02,920
+هذا بإيده نفسه الشيء مظبوط ولا لأ؟ طيب، we have
+
+258
+00:20:02,920 --> 00:20:06,780
+another term which it's called depreciation
+
+259
+00:20:06,780 --> 00:20:10,520
+الاهلاك، هلأ أنت شريط مكيني بعد شوية صار فيه له 
+
+260
+00:20:10,520 --> 00:20:14,780
+اهلاك أو suppose that we have a house after a
+
+261
+00:20:14,780 --> 00:20:18,060
+period of time it needs maintenance which go and
+
+262
+00:20:18,060 --> 00:20:21,640
+as a result due to the depreciation of the assets
+
+263
+00:20:21,640 --> 00:20:25,460
+صار فيه عنده اهلاك، هلأ الاهلاك هذه المدفوعات
+
+264
+00:20:25,460 --> 00:20:29,590
+تجزي أصلاً من الـ investment الأساسي مصبوط؟ and we
+
+265
+00:20:29,590 --> 00:20:37,190
+have net investment صافي الاستثمار yes
+
+266
+00:20:37,190 --> 00:20:42,170
+it's part of the gross investment yes because the
+
+267
+00:20:42,170 --> 00:20:47,590
+gross investment شباب gross investment equals the
+
+268
+00:20:47,590 --> 00:20:51,750
+net investment plus the depreciation يعني القانون
+
+269
+00:20:51,750 --> 00:20:53,610
+هذا اللي هو الـ gross investment
+
+270
+00:21:00,920 --> 00:21:06,080
+الـ Gross Investment Investment 
+
+271
+00:21:06,080 --> 00:21:12,300
+اللي هو الـ I أصلاً موجود عندنا بال .. بال .. بال 
+
+272
+00:21:12,300 --> 00:21:21,960
+formula في الـ GDP equals the net investment plus
+
+273
+00:21:21,960 --> 00:21:29,820
+depreciation depreciation 
+
+274
+00:21:29,820 --> 00:21:40,330
+.. okay لذلك إذا كان لدينا معلومات تحتوي
+
+275
+00:21:40,330 --> 00:21:47,470
+على نت انفسمنت ودبريشياشن يجب أن نقوم بالتخطيط من 
+
+276
+00:21:47,470 --> 00:21:51,830
+الـ Gross Investment اللي هو الـ I بقيمة
+
+277
+00:21:53,450 --> 00:21:56,990
+the collection or summation of net investment plus
+
+278
+00:21:56,990 --> 00:22:00,090
+depreciation يعني ممكن يجيك في سؤال يمعطيك اللي هو 
+
+279
+00:22:00,090 --> 00:22:02,730
+الـ net investment و الـ depreciation you have to
+
+280
+00:22:02,730 --> 00:22:05,950
+calculate الـ I by summation of net investment plus 
+
+281
+00:22:05,950 --> 00:22:15,350
+depreciation right تمام، أعتبر أنك لديك معلومات
+
+282
+00:22:15,350 --> 00:22:21,490
+وأنت تحب تخطيط الـ GDP لتخطيط الـ GDP إيه إيه إيه
+
+283
+00:22:21,490 --> 00:22:27,830
+إيه إيه إيه إيه إيه إيه إيه إيه
+
+284
+00:22:35,700 --> 00:22:41,400
+بالنسبة لك في هذه الحالة عليك تخطيط الـ I تخطيط الـ I كما
+
+285
+00:22:41,400 --> 00:22:46,620
+تعلم أنها مستخدمات الأسعار، إذا عندك إذا كنت لديك 
+
+286
+00:22:46,620 --> 00:22:48,420
+مستخدمات ومستخدمات ومستخدمات ومستخدمات ومستخدمات
+
+287
+00:22:48,420 --> 00:22:48,960
+ومستخدمات ومستخدمات ومستخدمات ومستخدمات ومستخدمات
+
+288
+00:22:48,960 --> 00:22:51,700
+ومستخدمات ومستخدمات ومستخدمات ومستخدمات ومستخدمات
+
+289
+00:22:51,700 --> 00:22:52,320
+ومستخدمات ومستخدمات ومستخدمات ومستخدمات ومستخدمات
+
+290
+00:22:52,320 --> 00:22:53,720
+ومستخدمات ومستخدمات ومستخدمات ومستخدمات ومستخدمات
+
+291
+00:22:53,720 --> 00:22:59,500
+ومستخدمات ومستخدمات ومستخدمات ومستخدم
+
+292
+00:22:59,630 --> 00:23:02,990
+C شو بتساوي؟ قولنا. durable goods, non-durable 
+
+293
+00:23:02,990 --> 00:23:05,530
+goods and services. يعني suppose that we have
+
+294
+00:23:05,530 --> 00:23:12,070
+information about the .. as we mentioned durable
+
+295
+00:23:12,070 --> 00:23:17,650
+goods, non-durable goods and services, we have to
+
+296
+00:23:17,650 --> 00:23:20,250
+calculate the summation of durable goods, non
+
+297
+00:23:20,250 --> 00:23:25,130
+-durable goods and services to reach C. صح؟ مظبوط
+
+298
+00:23:25,130 --> 00:23:27,450
+ولا لأ؟ جايين على الـ .. yes
+
+299
+00:23:33,030 --> 00:23:39,410
+لأ، إنها جزء من المبادرة، لأن كما تعلمين عندما ن
+
+300
+00:23:39,410 --> 00:23:46,410
+.. إنها جزء من الأسعار، إنها جزء من الأسعار لأن الـ
+
+301
+00:23:46,410 --> 00:23:49,850
+.. الـ
+
+302
+00:23:49,850 --> 00:23:50,390
+.. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ
+
+303
+00:23:50,390 --> 00:23:50,650
+الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ
+
+304
+00:23:50,650 --> 00:23:51,330
+.. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ ..
+
+305
+00:23:51,330 --> 00:23:52,690
+الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ
+
+306
+00:23:52,690 --> 00:23:52,730
+.. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ ..
+
+307
+00:23:52,730 --> 00:23:52,750
+الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ
+
+308
+00:23:52,750 --> 00:23:53,270
+.. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ ..
+
+309
+00:23:53,270 --> 00:23:53,390
+الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ
+
+310
+00:23:53,390 --> 00:23:58,190
+.. الـ لذلك نستخدم الـ Depreciation نستخدمها
+
+311
+00:23:58,190 --> 00:24:04,850
+كمعالجة لسلوك الهواتف والمبنى، فهي جزء من
+
+312
+00:24:04,850 --> 00:24:13,930
+الأسعار، صحيح؟ حسنًا، وماذا عن الـ G؟ الـ G هي
+
+313
+00:24:13,930 --> 00:24:21,690
+الوضع الحكومي التي تحتوي على تفعيل الـ Central 
+
+314
+00:24:21,690 --> 00:24:27,410
+Government وFederal Governments اللي هو الـ Non
+
+315
+00:24:27,410 --> 00:24:30,150
+-Central Governments اللي في الولايات المتحدة اللي
+
+316
+00:24:30,150 --> 00:24:33,070
+احنا عندنا one government وبالتالي تفعيل الـ Total
+
+317
+00:24:33,070 --> 00:24:35,650
+Spending of the Palestinian Government
+
+318
+00:24:40,020 --> 00:24:42,860
+as a G as a government spending اللي في الولايات
+
+319
+00:24:42,860 --> 00:24:46,400
+التانية أو في بعض المناطق التانية فيه ولايات نفقات
+
+320
+00:24:46,400 --> 00:24:49,200
+الحكومة المركزية ونفقات حكومة الولايات كله الـ
+
+321
+00:24:49,200 --> 00:24:51,920
+summation of the government spending or the
+
+322
+00:24:51,920 --> 00:24:54,780
+federal government and the or the central
+
+323
+00:24:54,780 --> 00:24:57,780
+government and non federal governments or the non
+
+324
+00:24:57,780 --> 00:25:01,200
+central governments in this case it's called what
+
+325
+00:25:01,750 --> 00:25:04,610
+or the states governments اللي هو حكومات الولايات
+
+326
+00:25:04,610 --> 00:25:07,790
+the summation of these expenses it's called the
+
+327
+00:25:07,790 --> 00:25:11,730
+government spending, right? so let's go to the
+
+328
+00:25:11,730 --> 00:25:15,390
+government consumption and the gross investment
+
+329
+00:25:15,390 --> 00:25:20,370
+counts the expenditures by federal state and the
+
+330
+00:25:20,370 --> 00:25:25,590
+local governments for final goods and services. كل
+
+331
+00:25:25,590 --> 00:25:29,330
+النفقات الحكومة بتدخل ضمن الـ government spending
+
+332
+00:25:29,330 --> 00:25:34,730
+تمام؟ الـ Consumption والـ Investment الـ Gross
+
+333
+00:25:34,730 --> 00:25:38,110
+Investment تبع مين؟ للحكومة، للـ government. Right?
+
+334
+00:25:39,390 --> 00:25:42,910
+مثل ماذا؟ أعتبر أن الحكومة قررت تبني مبنية جديدة
+
+335
+00:25:42,910 --> 00:25:47,110
+للاستثمارات الأخرى في هذه الحالة .. أو أعتبر أن
+
+336
+00:25:47,110 --> 00:25:51,650
+الحكومة قررت تشتري أسلوب أو تصنع أسلوب .. نعم
+
+337
+00:25:51,650 --> 00:25:54,550
+تشتري .. للاستثمارات الأخرى في هذه الحالة .. إنها جزء
+
+338
+00:25:54,550 --> 00:25:58,470
+من الاستثمار الكبير للحكومة، لكن عندما نتحدث عن
+
+339
+00:25:58,470 --> 00:26:01,510
+استخدام الحكومة أو استخدام الحكومة، في بعض الأحيان
+
+340
+00:26:01,510 --> 00:26:06,850
+يشترون ويصنعون طعام، ملابس، أشياء مستقبلية وشيء
+
+341
+00:26:06,850 --> 00:26:12,890
+مثل هذا، نعم، نعم، إنها جزء من الانتجار. نعم
+
+342
+00:26:12,890 --> 00:26:16,450
+بالضبط،
+
+343
+00:26:16,450 --> 00:26:21,570
+نعم، بالطبع، تمام،
+
+344
+00:26:21,570 --> 00:26:27,430
+نعم، نعم، الشيء الأخير هو الـ net exports اللي هو
+
+345
+00:26:27,430 --> 00:26:35,830
+export minus import. اسمه الـ net exports. دعونا
+
+346
+00:26:35,830 --> 00:26:37,150
+نعود إلى
+
+347
+00:26:41,900 --> 00:26:44,960
+استخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+348
+00:26:44,960 --> 00:26:45,380
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+349
+00:26:45,380 --> 00:26:45,860
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+350
+00:26:45,860 --> 00:26:46,580
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+351
+00:26:46,580 --> 00:26:47,960
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+352
+00:26:47,960 --> 00:26:48,740
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+353
+00:26:48,740 --> 00:26:49,220
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+354
+00:26:49,220 --> 00:26:54,760
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+355
+00:26:54,760 --> 00:27:03,980
+الاستخدام تجار أو استخدام الحيوانات اللي يحتوي على
+
+356
+00:27:03,980 --> 00:27:06,960
+أشخاص مستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+357
+00:27:06,960 --> 00:27:09,100
+ومستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+358
+00:27:09,100 --> 00:27:13,420
+ومستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+359
+00:27:13,420 --> 00:27:13,740
+ومستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+360
+00:27:13,740 --> 00:27:14,140
+ومستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+361
+00:27:14,140 --> 00:27:17,400
+ومستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+362
+00:27:17,400 --> 00:27:26,560
+ومستمر
+
+363
+00:27:27,400 --> 00:27:29,900
+What about the gross private domestic investment
+
+364
+00:27:29,900 --> 00:27:35,000
+I? As we mentioned it includes non-residential,
+
+365
+00:27:35,140 --> 00:27:38,800
+residential and change in business inventory. صح؟
+
+366
+00:27:39,250 --> 00:27:47,930
+مظبوط. طيب the total value is as you see 1543
+
+367
+00:27:47,930 --> 00:27:53,210
+.2 what about the gross or the government spending
+
+368
+00:27:53,210 --> 00:27:55,190
+or the government consumption and the gross
+
+369
+00:27:55,190 --> 00:27:58,830
+investment for the government.  الهجيه includes
+
+370
+00:27:58,830 --> 00:28:05,310
+federal government expenses and plus the state and
+
+371
+00:28:05,310 --> 00:28:09,260
+local governments العامة أو الحكومة التي تستخدمها
+
+372
+00:28:09,260 --> 00:28:13,880
+بالعامة بالعامة بالعامة بالعامة بالعامة بالعامة
+
+373
+00:28:13,880 --> 00:28:18,200
+بالعامة بالعامة بالعامة بالعامة بالعامة بالعامة
+
+374
+00:28:18,200 --> 00:28:18,480
+بالعامة بالعامة بالعامة بالعامة بالعامة بالعامة
+
+375
+00:28:18,480 --> 00:28:22,720
+بالعامة بالعامة بالعامة بالعامة بالعامة بالعامة
+
+376
+00:28:22,720 --> 00:28:22,820
+بالعامة بالعامة بالعامة بالعامة بالعامة بالعامة
+
+377
+00:28:22,820 --> 00:28:29,380
+بالعامة بالعامة بالعامة
+
+378
+00:28:29,380 --> 00:28:36,600
+بالعامة
+
+379
+00:28:38,980 --> 00:28:46,280
+1438.5 X minus M is minus as you see. The total
+
+380
+00:28:46,280 --> 00:28:53,660
+value is minus 4423.6. Which is the net export. So
+
+381
+00:28:53,660 --> 00:28:58,680
+the total Gross Domestic Production GDP equals
+
+382
+00:28:58,680 --> 00:29:05,860
+what? The summation of C plus I plus G plus net
+
+383
+00:29:05,860 --> 00:29:12,670
+export أيوه، هذا plus this plus plus equals the
+
+384
+00:29:12,670 --> 00:29:16,550
+total value as you see equals ten thousand four
+
+385
+00:29:16,550 --> 00:29:21,030
+hundred forty six. this is the total gross or the
+
+386
+00:29:21,030 --> 00:29:24,490
+gross domestic product by using what? the
+
+387
+00:29:24,490 --> 00:29:26,450
+expenditure approach. right
+
+388
+00:29:29,700 --> 00:29:36,340
+نعم، هذا مثال، في 2002، نعم، للولايات المتحدة، هذا
+
+389
+00:29:36,340 --> 00:29:41,800
+مثال، فقط لكي نعرف كيف نستخدم طريقة الاستثمار
+
+390
+00:29:41,800 --> 00:29:48,480
+لتخطيط الـ GDP، صحيح؟ فإذا كنا نستخدم طريقة
+
+391
+00:29:48,480 --> 00:29:52,640
+الاستثمار لتخطيط الـ GDP للفلسطين، يجب أن نتخطيط
+
+392
+00:29:52,640 --> 00:29:57,880
+ما؟ الصميمة لـ Personal Consumption Expenditure أو
+
+393
+00:29:57,880 --> 00:30:02,260
+Consumption من البيئة على الأشياء المستقبلية
+
+394
+00:30:02,260 --> 00:30:06,300
+والمستقبلية والمستقبلية والمستقبلية والمساعدات بلس الانتجار
+
+395
+00:30:06,300 --> 00:30:11,080
+الوطني الوطني بلس الانتجار الوطني الوطني بلس
+
+396
+00:30:11,080 --> 00:30:11,700
+الانتجار الوطني الوطني بلس الانتجار الوطني الوطني
+
+397
+00:30:11,700 --> 00:30:13,240
+بلس الانتجار الوطني الوطني بلس الانتجار الوطني
+
+398
+00:30:13,240 --> 00:30:17,460
+الوطني بلس الانتجار الوطني الوطني الوطني بلس
+
+399
+00:30:17,460 --> 00:30:19,640
+الانتجار الوطني الوطني الوطني الوطني الوطني الوطني
+
+400
+00:30:19,640 --> 00:30:24,820
+الوطني الوطني الوطني الوطني الوطني الوطني الـ Okay
+
+401
+00:30:24,820 --> 00:30:27,840
+نحن .. نحن لسنا نتكلم .. نحن اليوم لسنا .. نحن
+
+402
+00:30:27,840 --> 00:30:33,000
+لسنا نتكلم عن تجارب الدولة ولكن
+
+403
+00:30:33,000 --> 00:30:43,300
+سأخذ مثال آخر، سأعود إلى عملية لأعرف كيف أستخدام أو
+
+404
+00:30:43,300 --> 00:30:50,400
+كيف أتخيل الوضع الدولي باستخدام تجارب التجارب ولكن
+
+405
+00:30:50,400 --> 00:30:59,250
+لديها فكرة جديدة. حسنًا، دعونا نستمر في التكليف عن
+
+406
+00:30:59,250 --> 00:31:03,670
+GDP باستخدام تجارب الاستثمار. تعتبر أننا لدينا
+
+407
+00:31:03,670 --> 00:31:07,710
+المعلومات التالية عن اقتصاد
+
+408
+00:31:10,170 --> 00:31:13,550
+هذه المعلومات هي كما ترى مصادر مستقبلية مستقبلية
+
+409
+00:31:13,550 --> 00:31:18,810
+مستقبلية مستقبلية مستقبلية مستقبلية مستقبلية
+
+410
+00:31:18,810 --> 00:31:19,430
+مستقبلية مستقبلية مستقبلية مستقبلية مستقبلية
+
+411
+00:31:19,430 --> 00:31:23,210
+مستقبلية مستقبلية مستقبلية مستقبلية مستقبلية
+
+412
+00:31:23,210 --> 00:31:24,230
+مستقبلية مستقبلية مستقبلية مستقبلية مستقبلية
+
+413
+00:31:24,230 --> 00:31:36,430
+مستقبلية مستقبلية
+
+414
+00:31:36,610 --> 00:31:41,530
+كما تعلمين أن GDP يقل C إضافة إلى I إضافة إلى G
+
+415
+00:31:41,530 --> 00:31:47,370
+إضافة إلى X إضافة إلى M، لذلك يجب أن نتخيل C ثم I
+
+416
+00:31:47,370 --> 00:31:51,250
+ثم G مستخدم التحكم والخير الأخير هو الشركة
+
+417
+00:31:51,250 --> 00:31:54,010
+التجاربية. صحيح؟ كما ترون
+
+418
+00:31:57,790 --> 00:32:02,350
+equals what? a durable goods plus non durable goods
+
+419
+00:32:02,350 --> 00:32:06,070
+plus services equals one thousand six hundred
+
+420
+00:32:06,070 --> 00:32:11,550
+fifty. so as you see see the consumption equals a
+
+421
+00:32:11,550 --> 00:32:17,510
+durable goods plus non-durable goods, where is it?
+
+422
+00:32:17,510 --> 00:32:25,090
+the last one plus services, services, it's the 
+
+423
+00:32:25,090 --> 00:32:32,380
+consumption, right? و يجب أن نتخلص من I I يعني
+
+424
+00:32:32,380 --> 00:32:36,620
+الاستثمار الاستثمار الاستثمار يعني ماذا؟ كما ترى
+
+425
+00:32:36,620 --> 00:32:44,160
+هو الاستثمار اللي ليس مستقل مستقل
+
+426
+00:32:44,160 --> 00:32:48,720
+مستقل مستقل مستقل مستقل مستقل مستقل مستقل مستقل
+
+427
+00:32:48,720 --> 00:32:56,400
+مستقل مستقل نعم، بالضبط، لذلك مستقل لا يقل 300
+
+428
+00:32:56,400 --> 00:33:03,720
+مستقل لا يقل 50 وتغيير المصادر المشتركة لا يقل من
+
+429
+00:33:03,720 --> 00:33:11,720
+25، لذلك كما ترى I لا يقل 325، صحيح؟ ماذا عن
+
+430
+00:33:11,720 --> 00:33:16,440
+المحافظة الحكومية؟ المحافظة الحكومية يحتوي على
+
+431
+00:33:16,440 --> 00:33:26,570
+محافظة الوطنية شركات وشركات مجتمعية وشركات
+
+432
+00:33:26,570 --> 00:33:40,230
+مجتمعية وشركات مجتمعية وشركات
+
+433
+00:33:40,230 --> 00:33:47,540
+مجتمعية 250 مقارنة 550 مقارنة صحيح؟ لذلك كما ترى،
+
+434
+00:33:47,540 --> 00:33:53,760
+هذا الـ RG وماذا عن الـ Net Export؟ الـ Net Export
+
+435
+00:33:53,760 --> 00:33:56,840
+مقارنة بـ Exports مقارنة بـ Imports مقارنة بـ
+
+436
+00:33:56,840 --> 00:34:01,080
+Imports مقارنة بـ Imports مقارنة بـ Imports مقارنة
+
+437
+00:34:01,080 --> 00:34:08,420
+بـ Imports مقارنة بـ Imports
+
+438
+00:34:08,420 --> 00:34:10,020
+مقارنة بـ Imports مقارنة بـ Imports مقارنة بـ
+
+439
+00:34:10,020 --> 00:34:10,480
+Imports مقارنة بـ Imports مقارنة بـ Imports مقارنة
+
+440
+00:34:10,480 --> 00:34:10,500
+بـ Imports مقارنة بـ Imports مقارنة بـ Imports
+
+441
+00:34:10,500 --> 00:34:10,760
+Imports مقارنة بـ Imports مقارنة بـ Imp
+
+442
+00:34:14,520 --> 00:34:22,200
+500-150 يعني 350، هذا ما يسمى نت اكسبورت
+
+443
+00:34:25,940 --> 00:34:38,500
+الوضع الدولي يسمى C I G X M C GDP يسمى C I G X M
+
+444
+00:34:38,500 --> 00:34:43,600
+يسمى 2875
+
+445
+00:34:43,600 --> 00:34:52,880
+نعم نعم الاسم C I G X M هذا GDP
+
+446
+00:34:59,110 --> 00:35:11,810
+أسف .. أسف .. حسنا .. تعتبر .. تعتبر
+
+447
+00:35:11,810 --> 00:35:13,590
+.. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر ..
+
+448
+00:35:13,590 --> 00:35:13,710
+.. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر ..
+
+449
+00:35:13,710 --> 00:35:13,730
+تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر
+
+450
+00:35:13,730 --> 00:35:13,790
+.. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر ..
+
+451
+00:35:13,790 --> 00:35:13,810
+تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر
+
+452
+00:35:13,810 --> 00:35:14,930
+تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر
+
+453
+00:35:14,930 --> 00:35:16,470
+.. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر ..
+
+454
+00:35:16,470 --> 00:35:23,480
+تعتبر .. تعتبر .. مستخدمات مستخدمات مستخدمات
+
+455
+00:35:23,480 --> 00:35:25,100
+مستخدمات مستخدمات مستخدمات مستخدمات مستخدمات
+
+456
+00:35:25,100 --> 00:35:31,160
+مستخدمات مستخدمات مستخدمات مستخدمات مستخدمات
+
+457
+00:35:31,160 --> 00:35:37,920
+مستخدمات مستخدمات
+
+458
+00:35:37,920 --> 00:35:41,260
+مستخدمات
+
+459
+00:35:41,260 --> 00:35:47,200
+مستخدمات
+
+460
+00:35:49,540 --> 00:35:55,440
+لن يكون لدينا المعلومات عن هذه الثلاث أشياء أو
+
+461
+00:35:55,440 --> 00:36:02,700
+الواردات ولدينا نت انفسمنت وهذا هو نت انفسمنت
+
+462
+00:36:02,700 --> 00:36:06,300
+ولدينا 
+
+463
+00:36:06,300 --> 00:36:13,040
+مفارقة لتخطيط
+
+464
+00:36:13,040 --> 00:36:20,210
+I نت انفسمنت يعني ماذا نت انفسمنت مع مفارقة right?
+
+465
+00:36:20,210 --> 00:36:25,650
+here is the idea لأ
+
+466
+00:36:25,650 --> 00:36:28,830
+okay, in the next class إن شاء الله we are going to
+
+467
+00:36:28,830 --> 00:36:33,210
+talk about the calculations of income approach.
+
+468
+00:36:33,210 --> 00:36:34,390
+يعطيكم العثير 
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/8fHEZeTXGyo_postprocess.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/8fHEZeTXGyo_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..aad75646d06f0763ac524450beb76f6a383d02fb
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/8fHEZeTXGyo_postprocess.srt
@@ -0,0 +1,1872 @@
+1
+00:00:20,860 --> 00:00:24,240
+Okay بسم الله الرحمن الرحيم Today ان شاء الله we
+
+2
+00:00:24,240 --> 00:00:28,560
+are going to complete our talk about the GDP
+
+3
+00:00:28,560 --> 00:00:34,980
+calculationكما تعلمين في السلسلة السابقة تكتشفنا و
+
+4
+00:00:34,980 --> 00:00:41,000
+أشرحنا أننا لدينا إثنين طرح لتخطيط GDP الوضع
+
+5
+00:00:41,000 --> 00:00:48,080
+الدولي هذه الطرحين هي التجارب والثانية هي التجارب
+
+6
+00:00:48,080 --> 00:00:54,800
+الحيوانية لذلك اليوم دعونا نبدأ أو نبدأ بتجارب
+
+7
+00:00:54,800 --> 00:01:04,990
+التجارب لتخطيط GDP كما ذكرناعن طريق الاستخدام
+
+8
+00:01:04,990 --> 00:01:06,450
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+9
+00:01:06,450 --> 00:01:07,670
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+10
+00:01:07,670 --> 00:01:09,570
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+11
+00:01:09,570 --> 00:01:11,410
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+12
+00:01:11,410 --> 00:01:11,610
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+13
+00:01:11,610 --> 00:01:11,710
+الاستخدام الاستخدام الاستخدم الاستخدم الاستخدم
+
+14
+00:01:11,710 --> 00:01:13,810
+الاستخدم الاستخدم الاستخدم الاستخدم الاستخدم
+
+15
+00:01:13,810 --> 00:01:18,550
+الاستخدم
+
+16
+00:01:18,550 --> 00:01:23,870
+الاستخدم
+
+17
+00:01:23,870 --> 00:01:29,410
+الاستخد
+
+18
+00:01:30,680 --> 00:01:36,280
+هو الاستثمار الاستثمار الوطني الوطني الوطني الوطني
+
+19
+00:01:36,280 --> 00:01:38,200
+الوطني الوطني الوطني الوطني الوطني الوطني الوطني
+
+20
+00:01:38,200 --> 00:01:38,680
+الوطني الوطني الوطني الوطني الوطني الوطني الوطني
+
+21
+00:01:38,680 --> 00:01:39,260
+الوطني الوطني الوطني الوطني الوطني الوطني الوطني
+
+22
+00:01:39,260 --> 00:01:46,600
+الوطني الوطني الوطني الوطني
+
+23
+00:01:46,600 --> 00:01:48,660
+الوطني الوطني الوطني الوطني الوطني الوطني الوطني
+
+24
+00:01:48,660 --> 00:01:59,240
+الوطني الوطني الوطني
+
+25
+00:02:01,320 --> 00:02:10,600
+الحكومة تدفع او تدفع تجارب تدفع تجارب تدفع تجارب
+
+26
+00:02:10,600 --> 00:02:14,400
+تدفع تجارب
+
+27
+00:02:14,400 --> 00:02:14,440
+تدفع تجارب تدفع تجارب تدفع تجارب تدفع تجارب تدفع
+
+28
+00:02:14,440 --> 00:02:14,620
+تجارب تدفع تجارب تدفع تجارب تدفع تجارب تدفع تجارب
+
+29
+00:02:14,620 --> 00:02:15,120
+تجارب تدفع تجارب تدفع تجارب تدفع تدفع تجارب تدفع
+
+30
+00:02:15,120 --> 00:02:22,560
+تدفع تدفع تدفع تدفع تدفع تدفع تدفع تدفع تدفع ت
+
+31
+00:02:22,590 --> 00:02:30,410
+أخذ مهارة معينة أو مهارة معينة لتحسين GDP باستخدام
+
+32
+00:02:30,410 --> 00:02:36,690
+تجارب الاستثمار أو استخدام هذه الفرمولة، صحيح؟
+
+33
+00:02:36,690 --> 00:02:46,770
+حسنًا، كما ترىالخصائص الهجومية هي C I ثم G و X
+
+34
+00:02:46,770 --> 00:02:52,350
+مانوس MC لذلك دعونا ندفع الـ C او الهجوم الشخصي
+
+35
+00:02:52,350 --> 00:02:55,570
+الانفاق
+
+36
+00:02:55,570 --> 00:03:00,370
+الاستهلاكي الشخصي الذي هو الهيئة المستقبلية على
+
+37
+00:03:00,370 --> 00:03:05,350
+المواد المستخدمة استهلاك العائلة اللي يحتوي على
+
+38
+00:03:05,350 --> 00:03:13,260
+ثلاثة أشياء أهم أو ثلاثة أشياء أساسيةالسلع المعمرة
+
+39
+00:03:13,260 --> 00:03:21,900
+هي السلع المعمرة التي تستخدمها لشراء أشياء
+
+40
+00:03:21,900 --> 00:03:24,140
+مستقبلية ومساعدة مستقبلية ومساعدة مستقبلية ومساعدة
+
+41
+00:03:24,140 --> 00:03:26,520
+مستقبلية ومساعدة مستقبلية ومساعدة مستقبلية
+
+42
+00:03:26,520 --> 00:03:29,160
+ومستقبلية ومستقبلية ومستقبلية ومستقبلية ومستقبلية
+
+43
+00:03:29,160 --> 00:03:30,040
+ومستقبلية ومستقبلية ومستقبلية ومستقبلية ومستقبلية
+
+44
+00:03:30,040 --> 00:03:34,880
+ومستقبلية ومستقبلية
+
+45
+00:03:34,880 --> 00:03:39,960
+ومستقبل
+
+46
+00:03:40,000 --> 00:03:44,860
+والأشياء المستدامة مثل الطعام وملابس وشيء مثل هذا
+
+47
+00:03:44,860 --> 00:03:49,940
+وماذا عن المساعدات؟ المساعدات مثل المدير والعائلة
+
+48
+00:03:49,940 --> 00:03:55,580
+تستخدم مالها أو تشتري مجموعات مختلفة مثل
+
+49
+00:03:55,580 --> 00:04:00,680
+التليكوميكات والدراسات والصحة وما إلى ذلك، صح؟
+
+50
+00:04:00,680 --> 00:04:06,420
+الطوابق، بالضبط، نعم، لذا دعونا نشرح الـC أو
+
+51
+00:04:06,420 --> 00:04:12,910
+الانتجار الشخصيكما ترى، الانتجار الشخصي يتضمن
+
+52
+00:04:12,910 --> 00:04:15,790
+أشياء مستقبلية أو أشياء مستقبلية أو أشياء مستقبلية
+
+53
+00:04:15,790 --> 00:04:17,410
+أو أشياء مستقبلية أو أشياء مستقبلية أو أشياء
+
+54
+00:04:17,410 --> 00:04:18,030
+أشياء مستقبلية أو أشياء مستقبلية أو أشياء مستقبلية
+
+55
+00:04:18,030 --> 00:04:19,790
+أو أشياء مستقبلية أو أشياء مستقبلية أو أشياء
+
+56
+00:04:19,790 --> 00:04:23,250
+مستقبلية أو أشياء مستقبلية أو أشياء مستقبلية أو
+
+57
+00:04:23,250 --> 00:04:27,430
+أشياء مستقبلية أو أشياء مستقبلية أو أشياء مستقبلية
+
+58
+00:04:27,430 --> 00:04:36,560
+أو أشياء مستقبلية أو أشياء مsuch as the household
+
+59
+00:04:36,560 --> 00:04:42,010
+spending on food and clothingوماذا عن المساعدة؟
+
+60
+00:04:42,010 --> 00:04:46,650
+كما ترى أن المساعدة هي الأشياء التي لا تتعلق
+
+61
+00:04:46,650 --> 00:04:54,870
+بالتصنيف أو الأشياء التجارية مثل تقضية المدرسة،
+
+62
+00:04:54,870 --> 00:04:59,710
+تقضية الدراسة، تقضية الإلكتروسية، تقضية
+
+63
+00:04:59,710 --> 00:05:03,650
+التransportation وما إلى ذلك، صحيح؟ لذلك، هذا هو
+
+64
+00:05:03,650 --> 00:05:10,340
+المصطلح أو أشياء أساسية تقضية المساعدةفي الاقتصاد
+
+65
+00:05:10,340 --> 00:05:18,140
+اللي هو جزء من GDP باستخدام تجارب الاستخدام هل
+
+66
+00:05:18,140 --> 00:05:23,240
+هناك مشكلة حتى الآن؟ حسنًا، الجزء الثاني من الـ
+
+67
+00:05:23,240 --> 00:05:29,180
+GDP هو الاستثمار العملي، دعنا نعود إلى المفهوم أو
+
+68
+00:05:29,180 --> 00:05:37,750
+مفهوم الاستثمار العملي، كما ترىI هو الانتجار
+
+69
+00:05:37,750 --> 00:05:40,470
+الوطني الوطني الوطني الوطني الوطني الوطني الوطني
+
+70
+00:05:40,470 --> 00:05:42,530
+الوطني الوطني الوطني الوطني الوطني الوطني الوطني
+
+71
+00:05:42,530 --> 00:05:44,610
+الوطني الوطني الوطني الوطني الوطني الوطني الوطني
+
+72
+00:05:44,610 --> 00:05:45,890
+الوطني الوطني الوطني الوطني الوطني الوطني الوطني
+
+73
+00:05:45,890 --> 00:05:47,830
+الوطني الوطني الوطني الوطني الوطني الوطني الوطني
+
+74
+00:05:47,830 --> 00:05:51,450
+الوطني الوطني الوطني الوطني الوطني الوطني الوطني
+
+75
+00:05:51,450 --> 00:06:01,320
+الوطني الوطني الوطنيلذلك كما ترى انا او الاستثمار
+
+76
+00:06:01,320 --> 00:06:07,620
+العظيم يتضمن ايه؟ يتضمن شركات وعائلات التي تستخدم
+
+77
+00:06:07,620 --> 00:06:16,020
+الاستثمار مثل شراء اجهزة جديدة، شراء اجهزة مخصصة
+
+78
+00:06:16,020 --> 00:06:21,390
+جديدةinventory it's called inventory اللي هو
+
+79
+00:06:21,390 --> 00:06:26,230
+المخزون تبع ال .. ال .. what else? building a new
+
+80
+00:06:26,230 --> 00:06:32,430
+houses or it's called the .. yes or buying a new
+
+81
+00:06:32,430 --> 00:06:35,570
+inputs or factors production or like spare parts
+
+82
+00:06:35,570 --> 00:06:40,210
+material all of these things it's part of the
+
+83
+00:06:40,210 --> 00:06:46,870
+gross domestic investment right?لنذهب الى التفاصيل
+
+84
+00:06:46,870 --> 00:06:49,150
+المرتبطة بهذا الترمز
+
+85
+00:06:53,870 --> 00:06:59,350
+لذلك، كما ترى، الانبعاث يتعلق بالشراء مال جديد،
+
+86
+00:06:59,350 --> 00:07:05,050
+شراء رأس مال جديد، ما يسمى بالانبعاث كما ترى،
+
+87
+00:07:05,050 --> 00:07:10,410
+الانبعاث كامل بشركة خاصة يسمى الانبعاث خاصة خاصة
+
+88
+00:07:10,410 --> 00:07:11,690
+خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة
+
+89
+00:07:11,690 --> 00:07:12,270
+خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة
+
+90
+00:07:12,270 --> 00:07:13,210
+خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة
+
+91
+00:07:13,210 --> 00:07:13,970
+خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة خاصة
+
+92
+00:07:13,970 --> 00:07:17,600
+خاصة خاصة خاصة خاصة خاصة خأو تبني مبنى جديد و
+
+93
+00:07:17,600 --> 00:07:20,300
+مصادر و مصادر و مصادر و مصادر و مصادر و مصادر و
+
+94
+00:07:20,300 --> 00:07:22,340
+مصادر و مصادر و مصادر و مصادر و مصادر و مصادر و
+
+95
+00:07:22,340 --> 00:07:29,920
+مصادر و مصادر و مصادر و مصادر و مصادر و مصادر و
+
+96
+00:07:29,920 --> 00:07:33,300
+مصادر و مصادر و مصادر و مصادر و مصادر و مصادر و
+
+97
+00:07:33,300 --> 00:07:33,680
+مصادر و مصادر و مصادر و مصادر و مصادر و مصادر و
+
+98
+00:07:33,680 --> 00:07:41,120
+مصادر و مصادر و مصادر و مصادر و مصادر و مصادر و
+
+99
+00:07:41,120 --> 00:07:47,950
+مهذا هو الانتجار الكامل أو الانتجار الكامل أو
+
+100
+00:07:47,950 --> 00:07:54,750
+الانتجار الكبير وهذه هي المدى التي تم سوءها. لذا
+
+101
+00:07:54,750 --> 00:08:01,910
+لديناinventory this or the X's اللي هو هذا يعني ال
+
+102
+00:08:01,910 --> 00:08:04,670
+difference between the total production and the
+
+103
+00:08:04,670 --> 00:08:10,270
+amount sold ايش يسموه هذا ال X's او خلينا نسميه
+
+104
+00:08:10,270 --> 00:08:12,990
+هيك what's the difference between the total
+
+105
+00:08:12,990 --> 00:08:18,450
+production and sold كده ايش؟ two hundred cars هذا
+
+106
+00:08:18,450 --> 00:08:24,720
+وان بيروح؟ المخزونinventory yes exactly على المتين
+
+107
+00:08:24,720 --> 00:08:27,260
+سيارة هدولة two hundred cars بنحطهم في المخزون
+
+108
+00:08:27,260 --> 00:08:29,940
+وبالتالي صار في عندي a change in business
+
+109
+00:08:29,940 --> 00:08:32,920
+inventory صار في تغير في المخزون والتغير صار عندي
+
+110
+00:08:32,920 --> 00:08:38,420
+شماله positive صح؟ so in this case we have a
+
+111
+00:08:38,420 --> 00:08:41,400
+positive change in business inventory so that
+
+112
+00:08:41,400 --> 00:08:44,840
+change in business inventory is part of the gross
+
+113
+00:08:44,840 --> 00:08:49,080
+domestic product صح؟ لأن هو أصلا جزء من الانتاج
+
+114
+00:08:50,480 --> 00:08:56,400
+مصبوط ولا لأ؟ sometimes or that's it يعني this is
+
+115
+00:08:56,400 --> 00:09:05,720
+the inventory change and business inventory so the
+
+116
+00:09:05,720 --> 00:09:12,200
+GDP includes the total production not the total
+
+117
+00:09:12,200 --> 00:09:16,620
+sold صح؟ so the GDP
+
+118
+00:09:19,440 --> 00:09:27,800
+العامة العامة وليس العامة المجتمعة المجتمعة
+
+119
+00:09:27,800 --> 00:09:32,000
+المجتمعة
+
+120
+00:09:32,000 --> 00:09:35,820
+الأخيرة وليس العامة العامة العامة المجتمعة
+
+121
+00:09:35,820 --> 00:09:36,300
+المجتمعة المجتمعة المجتمعة المجتمعة المجتمعة
+
+122
+00:09:36,300 --> 00:09:37,560
+المجتمعة المجتمعة المجتمعة المجتمعة المجتمعة
+
+123
+00:09:37,560 --> 00:09:40,820
+المجتمعة المجتمعة المجتمعة المجتمعة
+
+124
+00:09:40,820 --> 00:09:45,980
+المجتمعة المجتمعة المجتمعة
+
+125
+00:09:47,890 --> 00:09:57,170
+Total Final Production Plus
+
+126
+00:09:57,170 --> 00:10:05,890
+GDP
+
+127
+00:10:05,890 --> 00:10:08,790
+Equals Total Quantity Sold
+
+128
+00:10:12,990 --> 00:10:14,670
+بالإضافة إلى تغيير المصادر العامة في المصادر
+
+129
+00:10:14,670 --> 00:10:16,150
+العامة في المصادر العامة في المصادر العامة في
+
+130
+00:10:16,150 --> 00:10:17,010
+المصادر العامة في المصادر العامة في المصادر العامة
+
+131
+00:10:17,010 --> 00:10:25,750
+في المصادر العامة في المصادر العامة في المصادر
+
+132
+00:10:25,750 --> 00:10:28,330
+العامة في المصادر العامة في المصادر العامة في
+
+133
+00:10:28,330 --> 00:10:30,270
+المصادر العامة في المصادر العامة في المصادر العامة
+
+134
+00:10:30,270 --> 00:10:31,470
+في المصادر العامة في المصادر العامة في المصادر
+
+135
+00:10:31,470 --> 00:10:31,970
+العامة في المصادر العامة في المصادر العامة في
+
+136
+00:10:31,970 --> 00:10:32,030
+المصادر العامة في المصادر العامة في المصادر العامة
+
+137
+00:10:32,030 --> 00:10:34,250
+في المصادر العامة في المصادر العامة في المصادر
+
+138
+00:10:34,250 --> 00:10:41,890
+العامة في المصادر العYes, this is the total
+
+139
+00:10:41,890 --> 00:10:49,930
+production. Right؟ So هذا بيشمل الـ final sold ..
+
+140
+00:10:49,930 --> 00:10:53,170
+produced .. sorry .. the final goods which have
+
+141
+00:10:53,170 --> 00:10:56,610
+been sold. Right؟ Plus the change in business
+
+142
+00:10:56,610 --> 00:11:00,910
+inventory. هي اللي بيعناها زاد الـ change ..
+
+143
+00:11:00,910 --> 00:11:03,350
+التغير اللي صار هذا بيعطينا هو الـ total
+
+144
+00:11:03,350 --> 00:11:06,430
+production which is the gross domestic product or
+
+145
+00:11:06,430 --> 00:11:07,350
+the total production. Yes.
+
+146
+00:11:10,340 --> 00:11:18,740
+yes suppose that in this case we have 700
+
+147
+00:11:18,740 --> 00:11:24,780
+cars suppose
+
+148
+00:11:24,780 --> 00:11:28,420
+this quantity or this amount is the previous
+
+149
+00:11:28,420 --> 00:11:34,480
+inventory right and we produced 1000 cars in this
+
+150
+00:11:34,480 --> 00:11:40,730
+year عندى أنا في المخزون أصلا سبعمية سيارةوراح
+
+151
+00:11:40,730 --> 00:11:46,750
+نامنتجين one thousand cars in this year and we
+
+152
+00:11:46,750 --> 00:11:53,970
+found that the demand in this year is one thousand
+
+153
+00:11:53,970 --> 00:11:57,330
+.. this is the demand or they sold .. they
+
+154
+00:11:57,330 --> 00:12:05,400
+quantized sold one thousand four hundredلذلك في
+
+155
+00:12:05,400 --> 00:12:09,000
+هذه الحالة هناك تغيير نقلي في مصادر المصادر كم؟
+
+156
+00:12:09,000 --> 00:12:13,540
+400 لذلك في هذه الحالة لدينا تغيير نقلي في مصادر
+
+157
+00:12:13,540 --> 00:12:20,420
+المصادر ب 400 لذلك كما ترى أكبر نوع مصادر المصادر
+
+158
+00:12:20,420 --> 00:12:24,060
+في هذه الحالة أو أكتر مصادر مصادر في هذه السنة يقل
+
+159
+00:12:24,060 --> 00:12:30,630
+1400 اكتر مصادر مصادر مصادر مصادرأعطاني إنتاج
+
+160
+00:12:30,630 --> 00:12:35,750
+السنة صح؟ So as you see the GDP or the total
+
+161
+00:12:35,750 --> 00:12:42,200
+production equals the total quantity soldplus the
+
+162
+00:12:42,200 --> 00:12:45,540
+change in business inventory which might be
+
+163
+00:12:45,540 --> 00:12:50,840
+positive or sometimes negative right so yes
+
+164
+00:12:50,840 --> 00:12:55,460
+exactly so in this case sold a quant sold plus the
+
+165
+00:12:55,460 --> 00:12:57,640
+change in business inventory which might be
+
+166
+00:12:57,640 --> 00:13:02,180
+negative and sometimes it would be positive right
+
+167
+00:13:02,180 --> 00:13:06,640
+so let's come back to the definitions and the
+
+168
+00:13:06,640 --> 00:13:14,260
+explanation for the terms okayهو واضح او انك تحتاج
+
+169
+00:13:14,260 --> 00:13:26,400
+شيء اكتر؟ كما
+
+170
+00:13:26,400 --> 00:13:31,840
+ذكرنا ان الاستثمار
+
+171
+00:13:31,840 --> 00:13:36,300
+الكبير يتضمن الاستثمار الكبير يتضمن
+
+172
+00:13:39,920 --> 00:13:44,600
+construction or residential investment, non
+
+173
+00:13:44,600 --> 00:13:48,780
+-residential investment and the change in business
+
+174
+00:13:48,780 --> 00:13:50,080
+inventories
+
+175
+00:14:00,260 --> 00:14:05,400
+الاستثمار عندما نتحدث عن الاستثمار في ال GDP نحن
+
+176
+00:14:05,400 --> 00:14:09,280
+نتحدث عن الاستثمار المشروع وليس الاستثمار المجلد
+
+177
+00:14:09,280 --> 00:14:14,020
+لذلك الاستثمار المشروع الاستثمار
+
+178
+00:14:14,020 --> 00:14:20,460
+اللي هو I يحتوي
+
+179
+00:14:20,460 --> 00:14:23,900
+على استثمار غير مستقل
+
+180
+00:14:30,600 --> 00:14:35,680
+plus residential investment
+
+181
+00:14:35,680 --> 00:14:45,890
+plus the change in inventory خليني أوضحهمالـ non
+
+182
+00:14:45,890 --> 00:14:50,010
+-residential investment اللي هو الاستثمار في أشياء
+
+183
+00:14:50,010 --> 00:14:54,810
+غير المساكن، غير المباني وهذا related to مين؟ to
+
+184
+00:14:54,810 --> 00:15:00,190
+the firms when they buy equipment, machines and so
+
+185
+00:15:00,190 --> 00:15:04,290
+on القطاع ال .. ال firms هذا بيشتري ال business
+
+186
+00:15:04,290 --> 00:15:07,470
+بيشتري equipment، this is part of investment it's
+
+187
+00:15:07,470 --> 00:15:12,170
+called non-residential investmentيسموه قطاع اللي
+
+188
+00:15:12,170 --> 00:15:15,590
+هو الاستثمار في إيش غير المساكن طب في إيش اسمه
+
+189
+00:15:15,590 --> 00:15:19,070
+residential investment residential investment اللي
+
+190
+00:15:19,070 --> 00:15:23,350
+هو استثمار the investment of the households and
+
+191
+00:15:23,350 --> 00:15:27,330
+the investment of firms or the business sector in
+
+192
+00:15:27,330 --> 00:15:32,250
+residential or construction so suppose you are as
+
+193
+00:15:32,250 --> 00:15:38,410
+a household sector decided to build a new housesin
+
+194
+00:15:38,410 --> 00:15:41,550
+this case it's part .. it's called the residential
+
+195
+00:15:41,550 --> 00:15:46,770
+investment إذا ال firms .. if the firms produces
+
+196
+00:15:46,770 --> 00:15:50,150
+or build also new houses for investment it's
+
+197
+00:15:50,150 --> 00:15:53,190
+called .. it's part of the residential investment
+
+198
+00:15:53,190 --> 00:15:58,260
+تمام؟والخير الأخير لـ Aggressive Investment هو
+
+199
+00:15:58,260 --> 00:16:02,240
+التغيير في الـ Business Inventory اللي تم تفضيله
+
+200
+00:16:02,240 --> 00:16:05,940
+أو تتكلم عنه الآن كما ترى فاهمينه التغيير في
+
+201
+00:16:05,940 --> 00:16:10,000
+Business Inventory؟ هل هو صحيح؟ لذلك دعونا نذهب
+
+202
+00:16:10,000 --> 00:16:13,240
+إلى التفريق بين الـ Residential و الـ Non
+
+203
+00:16:13,240 --> 00:16:17,560
+-residential و التغيير في Business Inventory كما
+
+204
+00:16:17,560 --> 00:16:23,290
+ترى التغيير في الـ Non-residential هوincludes
+
+205
+00:16:23,290 --> 00:16:27,550
+expenditures by the firms for machines, tools,
+
+206
+00:16:27,850 --> 00:16:31,950
+plants and so on what about the residential
+
+207
+00:16:31,950 --> 00:16:35,590
+investment residential investment includes
+
+208
+00:16:35,590 --> 00:16:39,930
+expenditures by who's by the households and the
+
+209
+00:16:39,930 --> 00:16:45,790
+firms on a new houses and apartment buildings تمام
+
+210
+00:16:46,610 --> 00:16:50,790
+والخير الأخير هو التغيير في الانفجار الخاص بالعمل
+
+211
+00:16:50,790 --> 00:16:54,630
+أو التغيير في الانفجار كما ذكرنا في المثال السابق
+
+212
+00:16:54,630 --> 00:17:00,350
+والأخير يقوم بتغيير قيمة من اي شركة انفجارها
+
+213
+00:17:00,350 --> 00:17:05,190
+تغييرها في مرحلة محددة كم تتخيل مخزوننا من مرحلة
+
+214
+00:17:05,190 --> 00:17:12,230
+لمرحلة انتجنا وبيعنا وهكذا فالانفجارات تحتوي على
+
+215
+00:17:12,230 --> 00:17:19,740
+شو الانفجارات تشملمواد عادية ومواد متوسطة ومواد
+
+216
+00:17:19,740 --> 00:17:23,850
+مخصصة للمواطنين ومواد عادية ومواد متوسطةاللي
+
+217
+00:17:23,850 --> 00:17:29,830
+suppose انه في firm عنده they imported او
+
+218
+00:17:29,830 --> 00:17:35,930
+purchased او imported raw material and spare parts
+
+219
+00:17:35,930 --> 00:17:38,070
+for the machines in order for .. for maintenance
+
+220
+00:17:38,070 --> 00:17:41,290
+purposes it's called .. it's part of the changing
+
+221
+00:17:41,290 --> 00:17:44,610
+business inventory or it's part of .. yes because
+
+222
+00:17:44,610 --> 00:17:48,570
+it will be used it's a .. it has been produced now
+
+223
+00:17:48,570 --> 00:17:54,700
+and it will be used later on صح؟واحد جايب قطع غيار
+
+224
+00:17:54,700 --> 00:17:58,200
+من برا للماكينة الموجود عنده قاعد بينتج فيها هذا
+
+225
+00:17:58,200 --> 00:18:01,520
+ايش بده يساوي بيحط القطع الغيار عنده في المخزن لما
+
+226
+00:18:01,520 --> 00:18:05,140
+بنحتاجها للماكينة لصيانة بده يستخدمها وبتالي هذا
+
+227
+00:18:05,140 --> 00:18:09,140
+أصلا it's part of it's called it's part of the
+
+228
+00:18:09,140 --> 00:18:11,920
+change in business inventory right okay
+
+229
+00:18:15,530 --> 00:18:21,390
+لذلك يجب أن نذكر أن الـ GDP ليس قيمة الأسعار
+
+230
+00:18:21,390 --> 00:18:25,470
+الأكتر من الأسعار الأكتر من الأسعار الأكتر من
+
+231
+00:18:25,470 --> 00:18:27,470
+الأسعار الأكتر من الأسعار الأكتر من الأسعار الأكتر
+
+232
+00:18:27,470 --> 00:18:28,830
+من الأسعار الأكتر من الأسعار الأكتر من الأسعار
+
+233
+00:18:28,830 --> 00:18:28,850
+الأكتر من الأسعار الأكتر من الأسعار الأكتر من
+
+234
+00:18:28,850 --> 00:18:29,070
+الأسعار الأكتر من الأسعار الأكتر من الأسعار الأكتر
+
+235
+00:18:29,070 --> 00:18:29,770
+من الأسعار الأكتر من الأسعار الأكتر من الأسعار
+
+236
+00:18:29,770 --> 00:18:30,370
+الأكتر من الأسعار الأكتر من الأسعار الأكتر من
+
+237
+00:18:30,370 --> 00:18:32,950
+الأسعار الأكتر من الأسعار الأكتر من الأسعار الأكتر
+
+238
+00:18:32,950 --> 00:18:37,210
+من الأسعار الأكتالسائق والتغيير في المصادر العامة،
+
+239
+00:18:37,210 --> 00:18:43,510
+صحيح؟ صحيح؟ لذلك عندما نتكلم عن GDP، لسنا نتكلم عن
+
+240
+00:18:43,510 --> 00:18:48,670
+قيم السوق لسائقنا، لكننا نتكلم عن قيم السوق كمية
+
+241
+00:18:48,670 --> 00:18:56,150
+المصادر أو الأشياء الأخيرة، صحيح؟ لذلك كما ترى
+
+242
+00:18:58,610 --> 00:19:01,390
+العلاقة بين تجارب المصادر والتجارب المصادرة
+
+243
+00:19:01,390 --> 00:19:01,870
+والتجارب المصادرة والتجارب المصادرة والتجارب
+
+244
+00:19:01,870 --> 00:19:03,830
+المصادرة والتجارب المصادرة والتجارب المصادرة
+
+245
+00:19:03,830 --> 00:19:07,450
+والتجارب المصادرة والتجارب المصادرة والتجارب
+
+246
+00:19:07,450 --> 00:19:11,230
+المصادرة والتجارب المصادرة والتجارب المصادرة
+
+247
+00:19:11,230 --> 00:19:13,650
+والتجارب المصادرة والتجارب المصادرة والتجارب
+
+248
+00:19:13,650 --> 00:19:13,690
+والتجارب المصادرة والتجارب المصادرة والتجارب
+
+249
+00:19:13,690 --> 00:19:15,870
+المصادرة والتجارب المصادرة والتجارب المصادرة
+
+250
+00:19:15,870 --> 00:19:20,850
+والتجارب المصادرة والتجارب المصادرة والتجار
+
+251
+00:19:23,180 --> 00:19:28,880
+Okay so I will talk or discuss everything slowly
+
+252
+00:19:28,880 --> 00:19:37,500
+slowly ان شاء الله don't worry okay okay So
+
+253
+00:19:37,500 --> 00:19:43,060
+let's go to the gross investment a gross
+
+254
+00:19:43,060 --> 00:19:48,330
+investment isthe total value of all in newly
+
+255
+00:19:48,330 --> 00:19:52,710
+produced capital goods like plant, equipment,
+
+256
+00:19:52,990 --> 00:19:56,690
+housing and inventory produced in a given period
+
+257
+00:19:56,690 --> 00:20:02,920
+هذا بإيد نفسه الإشي مظبوط ولا لأ؟طيب، we have
+
+258
+00:20:02,920 --> 00:20:06,780
+another term which it's called depreciation
+
+259
+00:20:06,780 --> 00:20:10,520
+الاهلاك، هلأ أنت شريط مكيني بعد شوية صار فيه له
+
+260
+00:20:10,520 --> 00:20:14,780
+اهلاك أو suppose that we have a house after a
+
+261
+00:20:14,780 --> 00:20:18,060
+period of time it needs maintenance which go and
+
+262
+00:20:18,060 --> 00:20:21,640
+as a result due to the depreciation of the assets
+
+263
+00:20:21,640 --> 00:20:25,460
+صار فيه عنده اهلاك، هلأ الاهلاك هذه المدفوعات
+
+264
+00:20:25,460 --> 00:20:29,590
+يجزوا أصلا من ال investment الأساسيمصبوط؟ and we
+
+265
+00:20:29,590 --> 00:20:37,190
+have net investment صافي الاستثمار yes
+
+266
+00:20:37,190 --> 00:20:42,170
+it's part of the gross investment yes because the
+
+267
+00:20:42,170 --> 00:20:47,590
+gross investment شباب gross investment equals the
+
+268
+00:20:47,590 --> 00:20:51,750
+net investment plus the depreciation يعني القانون
+
+269
+00:20:51,750 --> 00:20:53,610
+هذا اللي هو ال gross investment
+
+270
+00:21:00,920 --> 00:21:06,080
+الـ Gross Investment Investment
+
+271
+00:21:06,080 --> 00:21:12,300
+اللي هو الـ I أصلا موجود عندنا بال .. بال .. بال
+
+272
+00:21:12,300 --> 00:21:21,960
+formula في ال GDP equals the net investment plus
+
+273
+00:21:21,960 --> 00:21:29,820
+depreciation depreciation
+
+274
+00:21:29,820 --> 00:21:40,330
+.. okayلذلك إذا كان لدينا معلومات تحتوي
+
+275
+00:21:40,330 --> 00:21:47,470
+على نت انفسمنت ودبريشياشن يجب أن نقوم بالتخطيط من
+
+276
+00:21:47,470 --> 00:21:51,830
+الـ Gross Investment اللي هو الـ I بقيمة
+
+277
+00:21:53,450 --> 00:21:56,990
+the collection or summation of net investment plus
+
+278
+00:21:56,990 --> 00:22:00,090
+depreciation يعني ممكن يجيك في سؤال يمعطيك اللي هو
+
+279
+00:22:00,090 --> 00:22:02,730
+ال net investment و ال depreciation you have to
+
+280
+00:22:02,730 --> 00:22:05,950
+calculate ال I by summation of net investment plus
+
+281
+00:22:05,950 --> 00:22:15,350
+depreciation right تمام اهاعتبر انك لديك معلومات
+
+282
+00:22:15,350 --> 00:22:21,490
+وانت تحب تخطيط ال GDP لتخطيط ال GDP ايه ايه ايه
+
+283
+00:22:21,490 --> 00:22:27,830
+ايه ايه ايه ايه ايه ايه ايه ايه
+
+284
+00:22:35,700 --> 00:22:41,400
+بالنسبة لك في هذه الحالة عليك تخطيط I تخطيط I كما
+
+285
+00:22:41,400 --> 00:22:46,620
+تعلم أنها مستخدمات الأسعار إذا عندك إذا كنت لديك
+
+286
+00:22:46,620 --> 00:22:48,420
+مستخدمات ومستخدمات ومستخدمات ومستخدمات ومستخدمات
+
+287
+00:22:48,420 --> 00:22:48,960
+ومستخدمات ومستخدمات ومستخدمات ومستخدمات ومستخدمات
+
+288
+00:22:48,960 --> 00:22:51,700
+ومستخدمات ومستخدمات ومستخدمات ومستخدمات ومستخدمات
+
+289
+00:22:51,700 --> 00:22:52,320
+ومستخدمات ومستخدمات ومستخدمات ومستخدمات ومستخدمات
+
+290
+00:22:52,320 --> 00:22:53,720
+ومستخدمات ومستخدمات ومستخدمات ومستخدمات ومستخدمات
+
+291
+00:22:53,720 --> 00:22:59,500
+ومستخدمات ومستخدمات ومستخدمات ومستخدم
+
+292
+00:22:59,630 --> 00:23:02,990
+C شو بتساوي قولنا؟ durable goods, non-durable
+
+293
+00:23:02,990 --> 00:23:05,530
+goods and services يعني suppose that we have
+
+294
+00:23:05,530 --> 00:23:12,070
+information about the .. as we mentioned durable
+
+295
+00:23:12,070 --> 00:23:17,650
+goods, non-durable goods and services we have to
+
+296
+00:23:17,650 --> 00:23:20,250
+calculate the summation of durable goods, non
+
+297
+00:23:20,250 --> 00:23:25,130
+-durable goods and services to reach C صح؟ مظبوط
+
+298
+00:23:25,130 --> 00:23:27,450
+ولا لأ؟ جايين على ال .. yes
+
+299
+00:23:33,030 --> 00:23:39,410
+لأ، إنها جزء من المبادرة، لأن كما تعلمين عندما ن
+
+300
+00:23:39,410 --> 00:23:46,410
+.. إنها جزء من الأسعار، إنها جزء من الأسعار لأن ال
+
+301
+00:23:46,410 --> 00:23:49,850
+.. ال
+
+302
+00:23:49,850 --> 00:23:50,390
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+303
+00:23:50,390 --> 00:23:50,650
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+304
+00:23:50,650 --> 00:23:51,330
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+305
+00:23:51,330 --> 00:23:52,690
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+306
+00:23:52,690 --> 00:23:52,730
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+307
+00:23:52,730 --> 00:23:52,750
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+308
+00:23:52,750 --> 00:23:53,270
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+309
+00:23:53,270 --> 00:23:53,390
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+310
+00:23:53,390 --> 00:23:58,190
+.. ال ..لذلك نستخدم الـ Depreciation نستخدمها
+
+311
+00:23:58,190 --> 00:24:04,850
+كمعالجة لسلوك الهواتف و المبنى، فهي جزء من
+
+312
+00:24:04,850 --> 00:24:13,930
+الأسعار، صحيح؟ حسنًا، وماذا عن الـ G؟ الـ G هي
+
+313
+00:24:13,930 --> 00:24:21,690
+الوضع الحكوميالتي تحتوي على تفعيل الـ Central
+
+314
+00:24:21,690 --> 00:24:27,410
+Government وFederal Governments اللي هو الـ Non
+
+315
+00:24:27,410 --> 00:24:30,150
+-Central Governments اللي في الولايات المتحدة اللي
+
+316
+00:24:30,150 --> 00:24:33,070
+احنا عندنا one government وبالتالي تفعيل الـ Total
+
+317
+00:24:33,070 --> 00:24:35,650
+Spending of the Palestinian Government
+
+318
+00:24:40,020 --> 00:24:42,860
+as a G as a government spending اللي في الولايات
+
+319
+00:24:42,860 --> 00:24:46,400
+التانية أو في بعض المناطق التانية فيه ولايات نفقات
+
+320
+00:24:46,400 --> 00:24:49,200
+الحكومة المركزية ونفقات حكومة الولايات كله ال
+
+321
+00:24:49,200 --> 00:24:51,920
+summation of the government spending or the
+
+322
+00:24:51,920 --> 00:24:54,780
+federal government and the or the central
+
+323
+00:24:54,780 --> 00:24:57,780
+government and non federal governments or the non
+
+324
+00:24:57,780 --> 00:25:01,200
+central governments in this case it's called what
+
+325
+00:25:01,750 --> 00:25:04,610
+or the states governments اللي هو حكومات الولايات
+
+326
+00:25:04,610 --> 00:25:07,790
+the summation of these expenses it's called the
+
+327
+00:25:07,790 --> 00:25:11,730
+government spending right؟ so let's go to the
+
+328
+00:25:11,730 --> 00:25:15,390
+government consumption and the gross investment
+
+329
+00:25:15,390 --> 00:25:20,370
+counts the expenditures by federal state and the
+
+330
+00:25:20,370 --> 00:25:25,590
+local governments for final goods and services كل
+
+331
+00:25:25,590 --> 00:25:29,330
+النفقات الحكومة بتدخل ضمن ال government spending
+
+332
+00:25:29,330 --> 00:25:34,730
+تمام؟الـ Consumption والـ Investment الـ Gross
+
+333
+00:25:34,730 --> 00:25:38,110
+Investment تبع مين؟ للحكومة، لل government Right؟
+
+334
+00:25:39,390 --> 00:25:42,910
+مثل ماذا؟ اعترض ان الحكومة قررت تبني مبنية جديدة
+
+335
+00:25:42,910 --> 00:25:47,110
+لأستثمارات أخرى في هذه الحالة .. او اعترض ان
+
+336
+00:25:47,110 --> 00:25:51,650
+الحكومة قررت تشتري أسلوب أو تصنع أسلوب .. نعم
+
+337
+00:25:51,650 --> 00:25:54,550
+تشتري .. لأستثمارات أخرى في هذه الحالة .. انها جزء
+
+338
+00:25:54,550 --> 00:25:58,470
+من الاستثمار الكبير للحكومة، لكن عندما نتحدث عن
+
+339
+00:25:58,470 --> 00:26:01,510
+استخدام الحكومة أو استخدام الحكومة، في بعض الأحيان
+
+340
+00:26:01,510 --> 00:26:06,850
+يشترون ويصنعون طعام، ملابس، أشياء مستقبلية وشيء
+
+341
+00:26:06,850 --> 00:26:12,890
+مثل هذا،نعم ، نعم ، إنها جزء من الانتجار نعم
+
+342
+00:26:12,890 --> 00:26:16,450
+بالضبط،
+
+343
+00:26:16,450 --> 00:26:21,570
+نعم بالطبع تمام،
+
+344
+00:26:21,570 --> 00:26:27,430
+نعم ، نعم الشيء الأخير هو الـ net exports اللي هو
+
+345
+00:26:27,430 --> 00:26:35,830
+export minus import اسمه الـ net exports دعونا
+
+346
+00:26:35,830 --> 00:26:37,150
+نعود إلى
+
+347
+00:26:41,900 --> 00:26:44,960
+استخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+348
+00:26:44,960 --> 00:26:45,380
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+349
+00:26:45,380 --> 00:26:45,860
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+350
+00:26:45,860 --> 00:26:46,580
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+351
+00:26:46,580 --> 00:26:47,960
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+352
+00:26:47,960 --> 00:26:48,740
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+353
+00:26:48,740 --> 00:26:49,220
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+354
+00:26:49,220 --> 00:26:54,760
+الاستخدام تجارب الاستخدام تجارب الاستخدام تجارب
+
+355
+00:26:54,760 --> 00:27:03,980
+الاستخدام تجارأو استخدام الحيوانات اللي يحتوي على
+
+356
+00:27:03,980 --> 00:27:06,960
+أشخاص مستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+357
+00:27:06,960 --> 00:27:09,100
+ومستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+358
+00:27:09,100 --> 00:27:13,420
+ومستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+359
+00:27:13,420 --> 00:27:13,740
+ومستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+360
+00:27:13,740 --> 00:27:14,140
+ومستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+361
+00:27:14,140 --> 00:27:17,400
+ومستمرين ومستمرين ومستمرين ومستمرين ومستمرين
+
+362
+00:27:17,400 --> 00:27:26,560
+ومستمر
+
+363
+00:27:27,400 --> 00:27:29,900
+What about the gross private domestic investment
+
+364
+00:27:29,900 --> 00:27:35,000
+I? As we mentioned it includes non-residential,
+
+365
+00:27:35,140 --> 00:27:38,800
+residential and change in business inventory صح؟
+
+366
+00:27:39,250 --> 00:27:47,930
+مصبوط طيب the total value is as you see 1543
+
+367
+00:27:47,930 --> 00:27:53,210
+.2 what about the gross or the government spending
+
+368
+00:27:53,210 --> 00:27:55,190
+or the government consumption and the gross
+
+369
+00:27:55,190 --> 00:27:58,830
+investment for the government الهجيه includes
+
+370
+00:27:58,830 --> 00:28:05,310
+federal government expenses and plus the state and
+
+371
+00:28:05,310 --> 00:28:09,260
+local governmentsالعامة او الحكومة التي تستخدمها
+
+372
+00:28:09,260 --> 00:28:13,880
+بالعامة بالعامة بالعامة بالعامة بالعامة بالعامة
+
+373
+00:28:13,880 --> 00:28:18,200
+بالعامة بالعامة بالعامة بالعامة بالعامة بالعامة
+
+374
+00:28:18,200 --> 00:28:18,480
+بالعامة بالعامة بالعامة بالعامة بالعامة بالعامة
+
+375
+00:28:18,480 --> 00:28:22,720
+بالعامة بالعامة بالعامة بالعامة بالعامة بالعامة
+
+376
+00:28:22,720 --> 00:28:22,820
+بالعامة بالعامة بالعامة بالعامة بالعامة بالعامة
+
+377
+00:28:22,820 --> 00:28:29,380
+بالعامة بالعامة بالعامة
+
+378
+00:28:29,380 --> 00:28:36,600
+بالعامة
+
+379
+00:28:38,980 --> 00:28:46,280
+1438.5 X minus M is minus as you see The total
+
+380
+00:28:46,280 --> 00:28:53,660
+value is minus 4423.6 Which is the net export So
+
+381
+00:28:53,660 --> 00:28:58,680
+the total Gross Domestic Production GDP equals
+
+382
+00:28:58,680 --> 00:29:05,860
+what? The summation of C plus I plus G plus net
+
+383
+00:29:05,860 --> 00:29:12,670
+exportايوه هذا plus this plus plus equals the
+
+384
+00:29:12,670 --> 00:29:16,550
+total value as you see equals ten thousand four
+
+385
+00:29:16,550 --> 00:29:21,030
+hundred forty six this is the total gross or the
+
+386
+00:29:21,030 --> 00:29:24,490
+gross domestic product by using what the
+
+387
+00:29:24,490 --> 00:29:26,450
+expenditure approach right
+
+388
+00:29:29,700 --> 00:29:36,340
+نعم، هذا مثال، في 2002، نعم، للولايات المتحدة، هذا
+
+389
+00:29:36,340 --> 00:29:41,800
+مثال، فقط لكي نعرف كيف نستخدم طريقة الاستثمار
+
+390
+00:29:41,800 --> 00:29:48,480
+لتخطيط الـ GDP، صحيح؟ فإذا كنا نستخدم طريقة
+
+391
+00:29:48,480 --> 00:29:52,640
+الاستثمار لتخطيط الـ GDP للفلسطين، يجب أن نتخطيط
+
+392
+00:29:52,640 --> 00:29:57,880
+ما؟الصميمة لـ Personal Consumption Expenditure أو
+
+393
+00:29:57,880 --> 00:30:02,260
+Consumption من البيئة على الأشياء المستقبلية
+
+394
+00:30:02,260 --> 00:30:06,300
+والمستقبلية والمستقبلية والمساعدات بلس الانتجار
+
+395
+00:30:06,300 --> 00:30:11,080
+الوطني الوطني بلس الانتجار الوطني الوطني بلس
+
+396
+00:30:11,080 --> 00:30:11,700
+الانتجار الوطني الوطني بلس الانتجار الوطني الوطني
+
+397
+00:30:11,700 --> 00:30:13,240
+بلس الانتجار الوطني الوطني بلس الانتجار الوطني
+
+398
+00:30:13,240 --> 00:30:17,460
+الوطني بلس الانتجار الوطني الوطني الوطني بلس
+
+399
+00:30:17,460 --> 00:30:19,640
+الانتجار الوطني الوطني الوطني الوطني الوطني الوطني
+
+400
+00:30:19,640 --> 00:30:24,820
+الوطني الوطني الوطني الوطني الوطني الوطني الOkay
+
+401
+00:30:24,820 --> 00:30:27,840
+نحن .. نحن لسنا نتكلم .. نحن اليوم لسنا .. نحن
+
+402
+00:30:27,840 --> 00:30:33,000
+لسنا نتكلم عن تجارب الدولة ولكن
+
+403
+00:30:33,000 --> 00:30:43,300
+سأخذ مثال آخر سأعود إلى عملية لأعرف كيف أستخدام أو
+
+404
+00:30:43,300 --> 00:30:50,400
+كيف أتخيل الوضع الدولي باستخدام تجارب التجارب ولكن
+
+405
+00:30:50,400 --> 00:30:59,250
+لديها فكرة جديدةحسنًا دعونا نستمر في التكليف عن
+
+406
+00:30:59,250 --> 00:31:03,670
+GDP باستخدام تجارب الاستثمار. تعتبر أننا لدينا
+
+407
+00:31:03,670 --> 00:31:07,710
+المعلومات التالية عن اقتصاد
+
+408
+00:31:10,170 --> 00:31:13,550
+هذه المعلومات هي كما ترى مصادر مستقبلية مستقبلية
+
+409
+00:31:13,550 --> 00:31:18,810
+مستقبلية مستقبلية مستقبلية مستقبلية مستقبلية
+
+410
+00:31:18,810 --> 00:31:19,430
+مستقبلية مستقبلية مستقبلية مستقبلية مستقبلية
+
+411
+00:31:19,430 --> 00:31:23,210
+مستقبلية مستقبلية مستقبلية مستقبلية مستقبلية
+
+412
+00:31:23,210 --> 00:31:24,230
+مستقبلية مستقبلية مستقبلية مستقبلية مستقبلية
+
+413
+00:31:24,230 --> 00:31:36,430
+مستقبلية مستقبلية
+
+414
+00:31:36,610 --> 00:31:41,530
+كما تعلمين أن GDP يقل C إضافة إلى I إضافة إلى G
+
+415
+00:31:41,530 --> 00:31:47,370
+إضافة إلى X إضافة إلى M لذلك يجب أن نتخيل C ثم I
+
+416
+00:31:47,370 --> 00:31:51,250
+ثم G مستخدم التحكم والخير الأخير هو الشركة
+
+417
+00:31:51,250 --> 00:31:54,010
+التجاربية صحيح؟ كما ترون
+
+418
+00:31:57,790 --> 00:32:02,350
+equals what a durable goods plus non durable goods
+
+419
+00:32:02,350 --> 00:32:06,070
+plus services equals one thousand six hundred
+
+420
+00:32:06,070 --> 00:32:11,550
+fifty so as you see see the consumption equals a
+
+421
+00:32:11,550 --> 00:32:17,510
+durable goods plus non durable goods where is it
+
+422
+00:32:17,510 --> 00:32:25,090
+the last one plus services services it's the
+
+423
+00:32:25,090 --> 00:32:32,380
+consumption rightو يجب أن نتخلص من I I يعني
+
+424
+00:32:32,380 --> 00:32:36,620
+الاستثمار الاستثمار الاستثمار يعني ماذا؟ كما ترى
+
+425
+00:32:36,620 --> 00:32:44,160
+هو الاستثمار اللي ليس مستقل مستقل
+
+426
+00:32:44,160 --> 00:32:48,720
+مستقل مستقل مستقل مستقل مستقل مستقل مستقل مستقل
+
+427
+00:32:48,720 --> 00:32:56,400
+مستقل مستقلنعم، بالضبط، لذلك مستقل لا يقل 300
+
+428
+00:32:56,400 --> 00:33:03,720
+مستقل لا يقل 50 وتغيير المصادر المشتركة لا يقل من
+
+429
+00:33:03,720 --> 00:33:11,720
+25، لذلك كما ترى I لا يقل 325، صحيح؟ ماذا عن
+
+430
+00:33:11,720 --> 00:33:16,440
+المحافظة الحكومية؟ المحافظة الحكومية يحتوي على
+
+431
+00:33:16,440 --> 00:33:26,570
+محافظة الوطنيةشركات وشركات مجتمعية وشركات
+
+432
+00:33:26,570 --> 00:33:40,230
+مجتمعية وشركات مجتمعية وشركات
+
+433
+00:33:40,230 --> 00:33:47,540
+مجتمعية250 مقارنة 550 مقارنة صحيح؟ لذلك كما ترى،
+
+434
+00:33:47,540 --> 00:33:53,760
+هذا الـ RG وماذا عن الـ Net Export؟ الـ Net Export
+
+435
+00:33:53,760 --> 00:33:56,840
+مقارنة بـ Exports مقارنة بـ Imports مقارنة بـ
+
+436
+00:33:56,840 --> 00:34:01,080
+Imports مقارنة بـ Imports مقارنة بـ Imports مقارنة
+
+437
+00:34:01,080 --> 00:34:08,420
+بـ Imports مقارنة بـ Imports
+
+438
+00:34:08,420 --> 00:34:10,020
+مقارنة بـ Imports مقارنة بـ Imports مقارنة بـ
+
+439
+00:34:10,020 --> 00:34:10,480
+Imports مقارنة بـ Imports مقارنة بـ Imports مقارنة
+
+440
+00:34:10,480 --> 00:34:10,500
+بـ Imports مقارنة بـ Imports مقارنة بـ Imports
+
+441
+00:34:10,500 --> 00:34:10,760
+Imports مقارنة بـ Imports مقارنة بـ Imp
+
+442
+00:34:14,520 --> 00:34:22,200
+500-150 يعني 350، هذا ما يسمى نت اكسبورت
+
+443
+00:34:25,940 --> 00:34:38,500
+الوضع الدولي يسمى C I G X M C GDP يسمى C I G X M
+
+444
+00:34:38,500 --> 00:34:43,600
+يسمى 2875
+
+445
+00:34:43,600 --> 00:34:52,880
+نعم نعم الاسم C I G X M هذا GDP
+
+446
+00:34:59,110 --> 00:35:11,810
+أسف .. أسف .. حسنا .. تعتبر .. تعتبر
+
+447
+00:35:11,810 --> 00:35:13,590
+.. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر ..
+
+448
+00:35:13,590 --> 00:35:13,710
+.. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر ..
+
+449
+00:35:13,710 --> 00:35:13,730
+تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر
+
+450
+00:35:13,730 --> 00:35:13,790
+.. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر ..
+
+451
+00:35:13,790 --> 00:35:13,810
+تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر
+
+452
+00:35:13,810 --> 00:35:14,930
+تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر
+
+453
+00:35:14,930 --> 00:35:16,470
+.. تعتبر .. تعتبر .. تعتبر .. تعتبر .. تعتبر ..
+
+454
+00:35:16,470 --> 00:35:23,480
+تعتبر .. تعتبر ..مستخدمات مستخدمات مستخدمات
+
+455
+00:35:23,480 --> 00:35:25,100
+مستخدمات مستخدمات مستخدمات مستخدمات مستخدمات
+
+456
+00:35:25,100 --> 00:35:31,160
+مستخدمات مستخدمات مستخدمات مستخدمات مستخدمات
+
+457
+00:35:31,160 --> 00:35:37,920
+مستخدمات مستخدمات
+
+458
+00:35:37,920 --> 00:35:41,260
+مستخدمات
+
+459
+00:35:41,260 --> 00:35:47,200
+مستخدمات
+
+460
+00:35:49,540 --> 00:35:55,440
+لن يكون لدينا المعلومات عن هذه الثلاث أشياء أو
+
+461
+00:35:55,440 --> 00:36:02,700
+الواردات ولدينا نت انفسمنت وهذا هو نت انفسمنت
+
+462
+00:36:02,700 --> 00:36:06,300
+ولدينا
+
+463
+00:36:06,300 --> 00:36:13,040
+مفارقة لتخطيط
+
+464
+00:36:13,040 --> 00:36:20,210
+I نت انفسمنت يعني ماذا نت انفسمنت مع مفارقةright؟
+
+465
+00:36:20,210 --> 00:36:25,650
+here is the idea لأ
+
+466
+00:36:25,650 --> 00:36:28,830
+okay in the next class ان شاء الله we are going to
+
+467
+00:36:28,830 --> 00:36:33,210
+talk about the calculations of income approach
+
+468
+00:36:33,210 --> 00:36:34,390
+يعطيكم العثير
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/B1sxcr4enWA.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/B1sxcr4enWA.srt
new file mode 100644
index 0000000000000000000000000000000000000000..5b6c9361d5fdf74ee0cf8cbc628f88db132e9854
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/B1sxcr4enWA.srt
@@ -0,0 +1,1904 @@
+1
+00:00:20,650 --> 00:00:23,990
+بسم الله الرحمن الرحيم اليوم إن شاء الله سنقوم
+
+2
+00:00:23,990 --> 00:00:27,310
+باختيار بعض التدريبات وبعض التدريبات الواقعية
+
+3
+00:00:27,310 --> 00:00:35,870
+مرتبطة بالقصة 4 و5 قبل أن نكمل القصة 5 بشكل صحيح؟
+
+4
+00:00:35,870 --> 00:00:39,810
+لذلك لكي نتأكد أن كل شيء ماضي بشكل صحيح كل شيء
+
+5
+00:00:39,810 --> 00:00:43,190
+ماضي بشكل صحيح لذا دعونا نأخذ التدريبات التالية
+
+6
+00:00:44,070 --> 00:00:49,690
+تجعلها أسهل تفهيم الدراسة كما تشاهد في هذا المثال
+
+7
+00:00:49,690 --> 00:00:55,230
+أو في هذا التعليق إذا كانت عملية استخدام C 100
+
+8
+00:00:55,230 --> 00:01:08,410
+plus 0.8Y و I 50 المسألة هي مستوى الميزانية هو كم؟
+
+9
+00:01:08,410 --> 00:01:14,740
+كما تعلمي إذا لم يكن هناك حكومة، فإن الانتاج يحدث 
+
+10
+00:01:14,740 --> 00:01:20,260
+عندما Y يكوّن أسعار الانتاج، فإن الانتاج يكوّن
+
+11
+00:01:20,260 --> 00:01:24,460
+أسعار الانتاج وإذا لم يكن هناك حكومة، فإن أسعار
+
+12
+00:01:24,460 --> 00:01:30,000
+الانتاج يكوّن كم؟ C plus I، ففي الانتاج Y
+
+13
+00:01:37,140 --> 00:01:38,540
+YYYYYYYYYYYYYYYYYYY
+
+14
+00:01:49,250 --> 00:01:56,230
+-0.8y-0
+
+15
+00:01:56,230 --> 00:02:01,690
+.8y
+
+16
+00:02:01,690 --> 00:02:10,130
+-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y
+
+17
+00:02:10,130 --> 00:02:10,470
+-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y
+
+18
+00:02:10,470 --> 00:02:12,630
+-0.8y-0.8y-0.8
+
+19
+00:02:23,110 --> 00:02:28,550
+ماذا عن المستخدم في هذه الحالة؟ كم هو المستخدم؟
+
+20
+00:02:31,450 --> 00:02:36,850
+exactly yes yes yes aggregate expenditure equals c
+
+21
+00:02:36,850 --> 00:02:41,610
+plus i the aggregate income equals c plus s right
+
+22
+00:02:41,610 --> 00:02:46,430
+so as we mentioned that at equilibrium the
+
+23
+00:02:46,430 --> 00:02:49,390
+aggregate income equals aggregate expenditure
+
+24
+00:02:49,390 --> 00:02:52,550
+right or the aggregate output equals the aggregate
+
+25
+00:02:52,550 --> 00:02:58,470
+expenditure تخيّل قيمة الانتاج أو الانتاج المجموعة
+
+26
+00:02:58,470 --> 00:03:05,070
+في الانتاج الانتاج الانتاج الانتاج الانتاج
+
+27
+00:03:05,070 --> 00:03:09,230
+الانتاج الانتاج الانتاج الانتاج الانتاج
+
+28
+00:03:09,230 --> 00:03:12,150
+الانتاج الانتاج الانتاج الانتاج الانتاج
+
+29
+00:03:12,150 --> 00:03:13,090
+الانتاج الانتاج الانتاج الانتاج الانتاج
+
+30
+00:03:13,090 --> 00:03:21,710
+الانتاج الانتاج الانتاج الانتاج الانتاج ال
+
+31
+00:03:25,220 --> 00:03:28,340
+هذا هو إيكويليبريوم التخزين أو قيمة التخزين في
+
+32
+00:03:28,340 --> 00:03:36,580
+إيكويليبريوم إذا C equal 100 plus 0.8 times 750 كم
+
+33
+00:03:36,580 --> 00:03:45,320
+كده كده كده كده كده كده كده كده كده كده كده كده
+
+34
+00:03:45,320 --> 00:03:45,380
+كده كده كده كده كده كده كده كده كده كده كده كده
+
+35
+00:03:45,380 --> 00:03:46,380
+كده كده كده كده كده كده كده كده كده كده كده كده
+
+36
+00:03:46,380 --> 00:03:50,780
+كده كده
+
+37
+00:03:50,780 --> 00:03:57,130
+كده كده كده كده كده كده كده كده كد Saving equals Y
+
+38
+00:03:57,130 --> 00:04:07,510
+minus C So it should be 700 What about the
+
+39
+00:04:07,510 --> 00:04:12,550
+aggregate saving? Saving equals Y minus C when
+
+40
+00:04:12,550 --> 00:04:17,270
+there is no government So S saving equals Y minus
+
+41
+00:04:17,270 --> 00:04:23,700
+C السعر يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+42
+00:04:23,700 --> 00:04:24,540
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+43
+00:04:24,540 --> 00:04:25,380
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+44
+00:04:25,380 --> 00:04:25,580
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+45
+00:04:25,580 --> 00:04:25,700
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+46
+00:04:25,700 --> 00:04:26,700
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+47
+00:04:26,700 --> 00:04:46,540
+باستخدام Y يقوم باستخدام Y
+
+48
+00:04:51,290 --> 00:05:01,230
+كما تشاهد، فإن عملية التخزين يقل 1500 plus 0.75Y I
+
+49
+00:05:01,230 --> 00:05:07,470
+يقل 500 مليون دولار فالسؤال هو إذا كان عملية
+
+50
+00:05:07,470 --> 00:05:11,190
+التخزين يقل عملية التخزين في مستوى نسخة نسخة نسخة
+
+51
+00:05:11,190 --> 00:05:15,750
+نسخة نسخة
+
+52
+00:05:17,420 --> 00:05:22,700
+السؤال هو إذا 
+
+53
+00:05:22,700 --> 00:05:28,120
+S
+
+54
+00:05:28,120 --> 00:05:34,600
+أقل I، إذا S أقل I، إذا S أقل I، إذا S أقل I، إذا
+
+55
+00:05:34,600 --> 00:05:35,520
+S أقل I، إذا S أقل I، إذا S أقل I، إذا S أقل I،
+
+56
+00:05:35,520 --> 00:05:35,940
+إذا S أقل I، إذا S أقل I، إذا S أقل I، إذا S أقل
+
+57
+00:05:35,940 --> 00:05:36,880
+إذا S أقل I، إذا S أقل I، إذا S أقل I، إذا S أقل
+
+58
+00:05:36,880 --> 00:05:42,510
+I، إذا S when y equals aggregate expenditure C plus
+
+59
+00:05:42,510 --> 00:05:47,170
+S equals C plus I so deduction of C so S equals I
+
+60
+00:05:47,170 --> 00:05:51,270
+at equilibrium so the same we have to do the same
+
+61
+00:05:51,270 --> 00:05:54,790
+to derive the equilibrium aggregate output the
+
+62
+00:05:54,790 --> 00:05:57,950
+equilibrium aggregate output in this case equals C
+
+63
+00:05:57,950 --> 00:06:04,470
+plus I the same so in this case أمسح هذا
+
+64
+00:06:20,450 --> 00:06:25,710
+السؤال هو تخطيط الميزة التجارية أو الميزة
+
+65
+00:06:25,710 --> 00:06:29,670
+التجارية الاجتماعية عندما تخطيط الميزة التجارية 
+
+66
+00:06:29,670 --> 00:06:30,310
+أو الميزة التجارية
+
+67
+00:06:34,070 --> 00:06:42,270
+يكون y يكون c plus i في الانتاج يكون y يكون 1500
+
+68
+00:06:42,270 --> 00:06:48,950
+plus 0.75 y plus 500 مليون دولار في الانتاج يكون
+
+69
+00:06:48,950 --> 00:06:58,670
+y يكون 2000 plus 0.75 y يكون y يكون 2000 plus 0.75
+
+70
+00:06:58,670 --> 00:07:08,100
+y يكون Equals 2000 So Zero Point Yes 25Y Equals
+
+71
+00:07:08,100 --> 00:07:15,660
+2000 So Y Equals 8000 Million Dollars That's It So
+
+72
+00:07:15,660 --> 00:07:21,720
+At Equilibrium The Aggregate Output Equals 8000
+
+73
+00:07:21,720 --> 00:07:24,380
+Million Dollars How Much Is The Consumption In
+
+74
+00:07:24,380 --> 00:07:27,200
+This Case Dark Substitution Of The Consumption
+
+75
+00:07:27,200 --> 00:07:34,550
+Function صَحّلتخطيط أو تخطيط استخدام المجموعة C يقل 
+
+76
+00:07:34,550 --> 00:07:45,050
+كم؟ C يقل 1500 plus 0.75 times Y يقل 8000 مليون
+
+77
+00:07:45,050 --> 00:07:59,310
+دولار C يقل 1500 plus كم؟ هل أنت متأكد؟ 6000 مليون
+
+78
+00:07:59,310 --> 00:08:10,590
+دولار أو 7500 مليون دولار أو
+
+79
+00:08:10,590 --> 00:08:14,710
+7500 مليون دولار
+
+80
+00:08:17,160 --> 00:08:24,500
+-7500-500 يعني أن هذا هو المساعدة الأساسية أو 
+
+81
+00:08:24,500 --> 00:08:25,800
+المساعدة الأساسية
+
+82
+00:08:30,970 --> 00:08:36,210
+نعم، نفس الفكرة، نفس البرنامج. لذلك، دعنا نذهب إلى
+
+83
+00:08:36,210 --> 00:08:40,510
+هذه الفيجورة أو هذا البرنامج. كما ترى، هذا هو
+
+84
+00:08:40,510 --> 00:08:44,570
+عملية المساعدة العضلية. A عملية المساعدة العضلية
+
+85
+00:08:44,570 --> 00:08:52,350
+يعني C plus I وهذا Y. يحدث الانعكاس عندما Y يعني
+
+86
+00:08:52,350 --> 00:08:55,370
+عملية المساعدة العضلية. هذا عملية المساعدة العضلية
+
+87
+00:08:55,370 --> 00:08:56,310
+Y.
+
+88
+00:08:58,410 --> 00:08:59,910
+وهذا Y.
+
+89
+00:09:03,470 --> 00:09:07,550
+الإيكويليبريوم كما ترى يحدث عند Y إيكويليبريوم
+
+90
+00:09:07,550 --> 00:09:13,790
+اتساقط افعالية اجرية ايه؟ اذا كم هو ال .. او كم هو
+
+91
+00:09:13,790 --> 00:09:15,910
+ال .. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه
+
+92
+00:09:15,910 --> 00:09:16,730
+.. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه ..
+
+93
+00:09:16,730 --> 00:09:17,050
+اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه
+
+94
+00:09:17,050 --> 00:09:18,570
+.. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه ..
+
+95
+00:09:18,570 --> 00:09:20,010
+.. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه ..
+
+96
+00:09:20,010 --> 00:09:23,690
+اه .. اه .. اه .. اه .. اه ..
+
+97
+00:09:28,380 --> 00:09:34,820
+derive the aggregate expenditure function
+
+98
+00:09:34,820 --> 00:09:39,700
+as you know that the aggregate expenditure
+
+99
+00:09:39,700 --> 00:09:43,020
+function includes the autonomous aggregate
+
+100
+00:09:43,020 --> 00:09:47,540
+expenditure plus the slope of the function times y
+
+101
+00:09:50,000 --> 00:09:54,140
+او او او او او او او او او او او او او او او او او
+
+102
+00:09:54,140 --> 00:09:55,340
+او او او او او او او او او او او او او او او او او
+
+103
+00:09:55,340 --> 00:10:01,440
+او او او او او او او او او او او او او او او او او
+
+104
+00:10:01,440 --> 00:10:03,480
+او او او او او او او او او او او او او او او او او
+
+105
+00:10:03,480 --> 00:10:08,300
+او او او او او
+
+106
+00:10:11,510 --> 00:10:16,770
+هذه المقارنة على هذه المقارنة لكتابة مقارنة
+
+107
+00:10:16,770 --> 00:10:18,290
+الهزيمة التي تستخدمها
+
+108
+00:10:22,790 --> 00:10:28,070
+-150 over 200 This is the marginal propensity to
+
+109
+00:10:28,070 --> 00:10:32,990
+consume، صح؟ So aggregate expenditure function in
+
+110
+00:10:32,990 --> 00:10:36,430
+this case equals the autonomous aggregate
+
+111
+00:10:36,430 --> 00:10:42,870
+expenditure which equals 150 plus the MPC times Y,
+
+112
+00:10:43,010 --> 00:10:48,090
+صح؟ MPC equals how much? MPC in this case equals
+
+113
+00:10:49,470 --> 00:10:51,670
+السلوب بالضبط سلوب عملية عملية عملية عملية عملية
+
+114
+00:10:51,670 --> 00:10:54,030
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+115
+00:10:54,030 --> 00:10:55,690
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+116
+00:10:55,690 --> 00:10:55,990
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+117
+00:10:55,990 --> 00:10:56,930
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+118
+00:10:56,930 --> 00:10:57,570
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+119
+00:10:57,570 --> 00:10:57,590
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+120
+00:10:57,590 --> 00:10:58,190
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+121
+00:10:58,190 --> 00:11:18,650
+عملية عمل
+
+122
+00:11:19,860 --> 00:11:25,360
+At equilibrium mathematically حسبولنا ال Y وال
+
+123
+00:11:25,360 --> 00:11:25,960
+consumption
+
+124
+00:11:46,720 --> 00:12:00,760
+Y-0.25Y-0.25Y زي 0.75 Y يقل 150، ف Y يقل كم؟ 200،
+
+125
+00:12:00,760 --> 00:12:06,100
+بالضبط، يجب أن يكون 200، لأن الاتصال هو 200، كما
+
+126
+00:12:06,100 --> 00:12:11,580
+ترى، صحيح؟ ماذا 
+
+127
+00:12:11,580 --> 00:12:16,970
+آخر؟ calculate the investment multiplier or the
+
+128
+00:12:16,970 --> 00:12:19,950
+value of investment multiplier the question is
+
+129
+00:12:19,950 --> 00:12:25,390
+calculate the investment multiplier the investment
+
+130
+00:12:25,390 --> 00:12:29,130
+multiplier equals how much or what's what's the
+
+131
+00:12:29,130 --> 00:12:32,950
+formula of the investment multiplier one over
+
+132
+00:12:37,520 --> 00:12:42,320
+السؤال هو تخطيط المزيد من المستخدمين المستخدمين
+
+133
+00:12:42,320 --> 00:12:44,780
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+134
+00:12:44,780 --> 00:12:45,020
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+135
+00:12:45,020 --> 00:12:45,540
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+136
+00:12:45,540 --> 00:12:46,020
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+137
+00:12:46,020 --> 00:12:48,100
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+138
+00:12:48,100 --> 00:12:48,500
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+139
+00:12:48,500 --> 00:12:49,320
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+140
+00:12:49,320 --> 00:12:50,200
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+
+141
+00:12:50,200 --> 00:12:55,460
+المستخدمين المستخدمين المستخدمين
+
+142
+00:12:55,460 --> 00:13:00,330
+المستخدمين مع ذلك، الـ Investment Multiplier يقوم
+
+143
+00:13:00,330 --> 00:13:03,250
+بالتخلص من 1 على 1 مقارنة 1 مقارنة 1 مقارنة 1
+
+144
+00:13:03,250 --> 00:13:06,290
+مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1
+
+145
+00:13:06,290 --> 00:13:09,350
+مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1
+
+146
+00:13:09,350 --> 00:13:15,370
+مقارنة 1 مقارنة 1 مقارنة 1 مقارنة
+
+147
+00:13:20,410 --> 00:13:25,150
+1.33 مليون دولار، هذا يعني أنّه إذا ارتكب
+
+148
+00:13:25,150 --> 00:13:28,910
+الاستثمار أو الاستثمار المخطط ارتكب 1 مليون دولار،
+
+149
+00:13:28,910 --> 00:13:30,550
+فإنّ نسبة الاستثمار المخطط أو الاستثمار المخطط
+
+150
+00:13:30,550 --> 00:13:39,710
+سترتكب 1.33 مليون دولار، صح؟ حسناً؟ طيب، أعتقد أنّ
+
+151
+00:13:39,710 --> 00:13:42,090
+الاستثمار المخطط ارتكب
+
+152
+00:13:46,320 --> 00:13:51,780
+50 مليون دولار المسألة هي .. اعتبار أنّ الاستثمار
+
+153
+00:13:51,780 --> 00:13:58,480
+المخطط يزيد من 50 مليون دولار كم هو قيمة التغيير
+
+154
+00:13:58,480 --> 00:14:01,740
+في الاختصار التجريبي أو الاستثمار التجريبي يعني
+
+155
+00:14:01,740 --> 00:14:07,860
+اعتبار أنّ الاستثمار التجريبي يزيد من 50 مليون
+
+156
+00:14:07,860 --> 00:14:16,930
+دولار هذا دلتا I دلتا I يقل 50 مليون دولار صح؟
+
+157
+00:14:16,930 --> 00:14:22,310
+السؤال هو تخطيط أو نعم تخطيط التغيير في الانتاج
+
+158
+00:14:22,310 --> 00:14:27,910
+التجاري والتحكم في الانتاج التجاري الجديد على
+
+159
+00:14:27,910 --> 00:14:33,770
+الفيرمين أو على الفجر نفس الشيء نعم، لذلك كما
+
+160
+00:14:33,770 --> 00:14:40,730
+تعلمين أنّ دلتا Y عبر دلتا I أكثر من واحد عبر MPS أو
+
+161
+00:14:40,730 --> 00:14:47,390
+واحد مانوس MBC، لذلك دلتا Y مفروض أن دلتا I مفروض
+
+162
+00:14:47,390 --> 00:15:03,970
+أن دلتا
+
+163
+00:15:03,970 --> 00:15:17,820
+I مفروض أن دلتا I مع 0.75 مرة مرة مرة مرة مرة مرة
+
+164
+00:15:17,820 --> 00:15:18,040
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+165
+00:15:18,040 --> 00:15:18,240
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+166
+00:15:18,240 --> 00:15:18,560
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+167
+00:15:18,560 --> 00:15:18,880
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+168
+00:15:18,880 --> 00:15:19,600
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+169
+00:15:19,600 --> 00:15:20,480
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+170
+00:15:20,480 --> 00:15:24,380
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+171
+00:15:24,380 --> 00:15:31,870
+مرة مرة مرة مرة مرة مرة مرة 66.6% هذا ما هو
+
+172
+00:15:31,870 --> 00:15:34,830
+التغيير في الميزة التجارية أو الميزة التجارية
+
+173
+00:15:34,830 --> 00:15:40,310
+الخاصة بكفة ميزة التجارة الخاصة بكفة ميزة التجارة
+
+174
+00:15:40,310 --> 00:15:41,570
+الخاصة بكفة ميزة التجارة الخاصة بكفة ميزة التجارة
+
+175
+00:15:41,570 --> 00:15:47,110
+الخاصة بكفة ميزة التجارة الخاصة بكفة ميزة التجارة
+
+176
+00:15:47,110 --> 00:15:47,190
+الخاصة بكفة M
+
+177
+00:15:58,320 --> 00:16:01,980
+266.6 مليار دولار، وهذا هو الانقلاب الجديد، لذلك
+
+178
+00:16:01,980 --> 00:16:07,180
+نتوقع أن يكون هناك انقلاب جديد في هذه النقطة،
+
+179
+00:16:07,180 --> 00:16:13,960
+لذلك لدينا تغيير كامل أو تغيير أعلى من عملية
+
+180
+00:16:13,960 --> 00:16:18,520
+التجارب التجاربية، لذلك هذا هو تجارب التجارب
+
+181
+00:16:18,520 --> 00:16:21,760
+التجاربية 2 C plus I plus Delta I
+
+182
+00:16:25,870 --> 00:16:31,170
+and this is the new equilibrium output or income
+
+183
+00:16:31,170 --> 00:16:39,310
+yes exactly 66.6 is the increasing of aggregate
+
+184
+00:16:39,310 --> 00:16:41,890
+income or the increasing of aggregate output
+
+185
+00:17:02,420 --> 00:17:12,540
+القيمة المرتبطة بتغيير
+
+186
+00:17:12,540 --> 00:17:23,440
+equilibrium export حسناً
+
+187
+00:17:23,440 --> 00:17:26,800
+دعونا
+
+188
+00:17:26,800 --> 00:17:28,420
+نأخذ التالي
+
+189
+00:17:36,040 --> 00:17:38,960
+كما ترى لدينا المعلومات الثالثة مباشرة مباشرة
+
+190
+00:17:38,960 --> 00:17:44,280
+مباشرة مباشرة مباشرة
+
+191
+00:17:44,280 --> 00:17:47,060
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+192
+00:17:47,060 --> 00:17:48,340
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+193
+00:17:48,340 --> 00:17:48,620
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+194
+00:17:48,620 --> 00:17:48,840
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+195
+00:17:48,840 --> 00:17:50,320
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+196
+00:17:50,320 --> 00:18:00,540
+مباشرة مباشرة مباشرة مباشرة مباشرة
+
+197
+00:18:01,940 --> 00:18:10,300
+مبسطة مبسطة مبسطة مبسطة مبسطة مبسطة
+
+198
+00:18:10,300 --> 00:18:16,300
+مبسطة مبسطة مبسطة مبسطة
+
+199
+00:18:16,300 --> 00:18:23,220
+مبسطة مبسطة مبسطة مبسطة
+
+200
+00:18:23,220 --> 00:18:30,300
+مبسطة مبسطة مبسطة مبسطة مبسطة مبسطة مبسطة مبسطة
+
+201
+00:18:33,100 --> 00:18:36,020
+الانبعاد الوضعي يزيد من نفس المقاومة 50 مليون
+
+202
+00:18:36,020 --> 00:18:40,760
+دولار اتخاذ التغيير في الميزة التجارية نفس الفكرة
+
+203
+00:18:40,760 --> 00:18:47,660
+لذا دلتا Y على دلتا I أكثر من 1 على MPS لذلك دلتا
+
+204
+00:18:47,660 --> 00:18:53,560
+Y على دلتا I 50 أكثر من 1 على 0.70
+
+205
+00:18:55,920 --> 00:19:05,020
+دلتا Y أكثر من 50 أكثر من 0.70 أكثر من 71
+
+206
+00:19:05,020 --> 00:19:09,820
+.4
+
+207
+00:19:15,040 --> 00:19:18,840
+بالتالي، الانقراض كما ترى، الانقراض من قيمة الـ
+
+208
+00:19:18,840 --> 00:19:23,240
+MBC الـ Marginal Propensity Consumed يتسبب في انقراض
+
+209
+00:19:23,240 --> 00:19:27,020
+القيمة أو التغيير في الميزة التجارية أو الميزة
+
+210
+00:19:27,020 --> 00:19:30,940
+التجارية صح؟ في المرة الأولى، الـ MBC في الحالة
+
+211
+00:19:30,940 --> 00:19:35,700
+السابقة، عندما ميزة الـ MBC كانت 0.25 ميزة كم هي
+
+212
+00:19:35,700 --> 00:19:39,540
+انقراض الميزة التجارية؟ 66.6 ميزة تجارية، صح؟ لكنّ
+
+213
+00:19:39,540 --> 00:19:44,080
+الآن، انقراض MBC يتسبب في انقراض الميزة التجارية
+
+214
+00:19:49,000 --> 00:19:55,980
+الشيء نفسه ..الشيء نفسه ..الشيء نفسه
+
+215
+00:19:55,980 --> 00:19:59,620
+..الشيء نفسه
+
+216
+00:19:59,620 --> 00:20:01,840
+..الشيء نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء
+
+217
+00:20:01,840 --> 00:20:03,560
+نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء نفسه
+
+218
+00:20:03,560 --> 00:20:03,900
+..الشيء نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء
+
+219
+00:20:03,900 --> 00:20:04,080
+..الشيء نفسه ..الشيء نفسه ..الشيء نفسه ..
+
+220
+00:20:12,870 --> 00:20:15,990
+في السابق .. نعم .. نعم .. نعم .. نعم .. في السابق
+
+221
+00:20:15,990 --> 00:20:26,230
+عندما MBC كانت 0.25 MPS 0.75 .. الآن عندما MBC أقل
+
+222
+00:20:26,230 --> 00:20:37,950
+0.30 MPS أقل 0.70 .. هذا هو .. حسناً؟ لا .. حسناً ..
+
+223
+00:20:37,950 --> 00:20:41,630
+MBC aggregate equilibrium
+
+224
+00:20:43,690 --> 00:20:49,470
+حسناً دعونا نذهب إلى هذا المثال السؤال
+
+225
+00:20:49,470 --> 00:20:57,110
+هو اعتمد أنّه لا يوجد حكومة أو مجتمع غير مجتمع لذلك
+
+226
+00:20:57,110 --> 00:21:03,530
+لا يوجد حكومة ونعمل تحت اقتصاد مغلق إذا
+
+227
+00:21:03,530 --> 00:21:07,870
+كتابة الـ Multiplier هو أو يقل 10 كتابة الـ
+
+228
+00:21:07,870 --> 00:21:09,610
+Multiplier
+
+229
+00:21:13,220 --> 00:21:18,180
+10 مليون دولار تقريباً 10 مليون دولار تقريباً
+
+230
+00:21:18,180 --> 00:21:18,960
+تقريباً 10 مليون دولار تقريباً 10 مليون دولار
+
+231
+00:21:18,960 --> 00:21:22,120
+تقريباً 10 مليون دولار تقريباً 10 مليون دولار
+
+232
+00:21:22,120 --> 00:21:24,920
+تقريباً 10 مليون دولار تقريباً 10 مليون دولار
+
+233
+00:21:24,920 --> 00:21:28,660
+تقريباً 10 مليون دولار تقريباً 10 مليون دولار
+
+234
+00:21:28,660 --> 00:21:35,440
+تقريباً 10 مليون دولار تقريباً 10
+
+235
+00:21:35,440 --> 00:21:42,020
+مليون دولار تقريباً السؤال هو تخطيط التغيير في الـ
+
+236
+00:21:42,020 --> 00:21:44,060
+aggregate output أو الاتجار التجاري أو الاتجار
+
+237
+00:21:44,060 --> 00:21:45,520
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+238
+00:21:45,520 --> 00:21:48,720
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+239
+00:21:48,720 --> 00:21:50,440
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+240
+00:21:50,440 --> 00:21:53,000
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+241
+00:21:53,000 --> 00:21:54,400
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+242
+00:21:54,400 --> 00:21:55,180
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+243
+00:21:55,180 --> 00:21:55,580
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+244
+00:21:55,580 --> 00:21:58,160
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+245
+00:21:58,160 --> 00:22:04,640
+التجاري أو
+
+246
+00:22:04,640 --> 00:22:11,570
+الاتجار التجاري صح or to ignore this part so
+
+247
+00:22:11,570 --> 00:22:16,710
+multiplier 10 equals delta y over 10 so delta y
+
+248
+00:22:16,710 --> 00:22:20,530
+equals positive this is positive positive one
+
+249
+00:22:20,530 --> 00:22:23,650
+hundred so we expect that the aggregate output
+
+250
+00:22:23,650 --> 00:22:27,610
+would increase by one hundred billion dollars
+
+251
+00:22:27,610 --> 00:22:34,750
+right yes يربعبس الواحد على واحد مانس MBC والله
+
+252
+00:22:34,750 --> 00:22:38,710
+عندي .. ال one .. the multiplier equals one over
+
+253
+00:22:38,710 --> 00:22:43,330
+.. one minus MBC, so one minus MBC is MPS حسب
+
+254
+00:22:43,330 --> 00:22:45,470
+الموضوع .. حسب الموضوع .. yes it depends .. yes
+
+255
+00:22:45,470 --> 00:22:53,110
+exactly طيب and this .. and this exercise what do
+
+256
+00:22:53,110 --> 00:22:59,380
+you see لسنا لدينا حكومة وليس لدينا عالم خارق إذا
+
+257
+00:22:59,380 --> 00:23:05,740
+كان مبيعات الـ MPS 0.2 مبيعات الـ MPS 0.2 مبيعات
+
+258
+00:23:05,740 --> 00:23:08,240
+الـ MPS 0.2 مبيعات الـ MPS 0.2 مبيعات الـ MPS 0.2
+
+259
+00:23:08,240 --> 00:23:08,560
+مبيعات الـ MPS 0.2 مبيعات الـ MPS 0.2 مبيعات الـ
+
+260
+00:23:08,560 --> 00:23:10,320
+MPS 0.2 مبيعات الـ MPS 0.2 مبيعات الـ MPS 0.2
+
+261
+00:23:10,320 --> 00:23:12,440
+مبيعات الـ MPS 0.2 مبيعات الـ MPS 0.2 مبيعات الـ
+
+262
+00:23:12,440 --> 00:23:17,550
+MPS 0.2 لذلك في هذه الحالة بيكسل بيكسل بيكسل
+
+263
+00:23:17,550 --> 00:23:18,150
+بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل
+
+264
+00:23:18,150 --> 00:23:21,670
+بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل
+
+265
+00:23:21,670 --> 00:23:30,750
+بيكسل بيكسل
+
+266
+00:23:31,340 --> 00:23:36,840
+عشان تعرف أن دلتا Y عشان دلتا I اكوال 1 عشان MPS
+
+267
+00:23:36,840 --> 00:23:43,320
+أو 1 مانوس MBC دلتا Y عشان مانوس مانوس مانوس مانوس
+
+268
+00:23:43,320 --> 00:23:45,680
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+269
+00:23:45,680 --> 00:23:47,100
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+270
+00:23:47,100 --> 00:23:48,820
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+271
+00:23:48,820 --> 00:23:48,860
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+272
+00:23:48,860 --> 00:24:00,300
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مان
+
+273
+00:24:02,340 --> 00:24:10,340
+so sorry no to decrease pie yes yes so we expect
+
+274
+00:24:10,340 --> 00:24:14,080
+that we have a decrease in aggregate output by 200
+
+275
+00:24:14,080 --> 00:24:20,400
+million دولار sorry جايين لل government لا لسنا
+
+276
+00:24:20,400 --> 00:24:25,120
+نتكلم عن الحكومة، لسنا لدينا حكومة هنا، حسناً؟
+
+277
+00:24:25,120 --> 00:24:31,500
+حسناً، دعنا نذهب و نأخذ أو نأخذ بعض التعليمات لقصة
+
+278
+00:24:31,500 --> 00:24:37,060
+5 عندما نضيف الحكومة و مستخدم الـ aggregate، حسناً؟
+
+279
+00:24:43,280 --> 00:24:47,700
+كما تشاهد في هذا المثال، عملي الـ Pell هو 1000$
+
+280
+00:24:47,700 --> 00:24:54,080
+وعقله الـ net taxes هي 35350$ وعقله الـ disposable 
+
+281
+00:24:54,080 --> 00:24:59,740
+disposable income هو كم؟ عملي الـ disposable income هو YD يقل
+
+282
+00:24:59,740 --> 00:25:10,440
+Y-T لذلك YD يقل 1000-350 يقل 650
+
+283
+00:25:13,150 --> 00:25:19,170
+right this is the first بلاش ييجي زيّي و دي يجي
+
+284
+00:25:19,170 --> 00:25:29,410
+أصعب علمك الأصعب هنا عشان ما yes exactly طيب
+
+285
+00:25:29,410 --> 00:25:37,040
+in this example in 2007المدينة كامفيل قمت بتجميع
+
+286
+00:25:37,040 --> 00:25:45,600
+500 ألف دولار من التجارب التجارب تي اكواس 500 ألف
+
+287
+00:25:45,600 --> 00:25:47,320
+مليون دولار أو دولار
+
+288
+00:26:03,700 --> 00:26:10,000
+We have a deficit because the taxes gained
+
+289
+00:26:10,000 --> 00:26:13,660
+or received is larger than the government spending
+
+290
+00:26:13,660 --> 00:26:17,880
+So we have a surplus by how much the difference
+
+291
+00:26:17,880 --> 00:26:22,440
+between G and T صح؟ مين أكبر؟ الإنفاق ولا الضريبة
+
+292
+00:26:22,440 --> 00:26:25,800
+اللي جمعناها؟ مجمعين ضريب، لذا we have a surplus
+
+293
+00:26:25,800 --> 00:26:28,820
+by fifty thousand dollars
+
+294
+00:26:34,100 --> 00:26:43,000
+حسنًا دعونا نذهب إلى هذا المثال أو التعليم كما
+
+295
+00:26:43,000 --> 00:26:51,380
+ترى عملية استخدام المجموعة هي C يكوين 100 plus 0
+
+296
+00:26:51,380 --> 00:27:01,320
+.6YD ماذا أخر؟ المال Y يكوين 1000 وY يكوين 1000
+
+297
+00:27:01,320 --> 00:27:13,250
+دولار، والوضع الضريبي هو T يقل 300$ يقل كم؟ YD أو
+
+298
+00:27:13,250 --> 00:27:21,830
+يمكننا استخدام الفورمولا C يقل 100 plus 0.6 YD YD
+
+299
+00:27:21,830 --> 00:27:31,460
+يقل Y minus T تغيير YD يقل Y minus T yes exactly so
+
+300
+00:27:31,460 --> 00:27:35,980
+c equals one hundred plus zero point six times y
+
+301
+00:27:35,980 --> 00:27:42,020
+minus the taxes three hundred right so what
+
+302
+00:27:42,020 --> 00:27:46,400
+do you see so c equals one hundred so y is given
+
+303
+00:27:46,400 --> 00:27:52,240
+exactly sorry yes y is given one thousand dollars
+
+304
+00:27:53,050 --> 00:28:02,270
+So C equals 100 plus 0.6 times 700 So C equals 100
+
+305
+00:28:02,270 --> 00:28:06,310
+plus 420
+
+306
+00:28:06,310 --> 00:28:15,070
+So C equals 520 Right Is
+
+307
+00:28:15,070 --> 00:28:25,270
+it clear طيب How much is the saving بالضبط كما
+
+308
+00:28:25,270 --> 00:28:29,210
+تعلمين إذا كان لدينا حكومة إذا كان هناك حكومة
+
+309
+00:28:29,210 --> 00:28:38,130
+يكوين C بلس S بلس T لأن جزء من حصتك يذهب للعيارات
+
+310
+00:28:38,130 --> 00:28:44,570
+لذلك لكي تتخيل حفظ في هذه الحالة حفظ يكوين Y minus
+
+311
+00:28:44,570 --> 00:28:53,960
+T minus C أو YD minus C So saving equals YD
+
+312
+00:28:53,960 --> 00:29:01,640
+minus C أو Y minus T minus C That's it So
+
+313
+00:29:01,640 --> 00:29:13,040
+S equals Y equals 1000 minus T taxes 300 minus C
+
+314
+00:29:13,040 --> 00:29:15,920
+520 صح
+
+315
+00:29:19,100 --> 00:29:22,380
+520 مقارنة بمقارنة مقارنة مقارنة مقارنة مقارنة
+
+316
+00:29:22,380 --> 00:29:23,780
+مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة
+
+317
+00:29:23,780 --> 00:29:33,800
+مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة
+
+318
+00:29:33,800 --> 00:29:45,160
+مقارنة
+
+319
+00:29:47,010 --> 00:29:51,550
+ولكن هنا يجب أن يكون مرتبط بـ YD بالضبط، لذلك
+
+320
+00:29:51,550 --> 00:29:57,150
+الاختيار في هذه الحالة يقل a plus b times YD وليس
+
+321
+00:29:57,150 --> 00:30:04,960
+Y أو مانوس اي بلس اكي بلس وان مانوس بي مبس مبس مبس
+
+322
+00:30:04,960 --> 00:30:08,660
+مبس وي دي مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+323
+00:30:08,660 --> 00:30:08,680
+مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+324
+00:30:08,680 --> 00:30:09,860
+مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+325
+00:30:09,860 --> 00:30:13,360
+مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+326
+00:30:13,360 --> 00:30:26,840
+مبس مبس مبس مب
+
+327
+00:30:27,070 --> 00:30:36,350
+-100 plus 40YD صح the same so let's go to another
+
+328
+00:30:36,350 --> 00:30:38,590
+exercise or example
+
+329
+00:30:45,650 --> 00:30:50,970
+هنا لدينا عملية استخدام المجتمع C يقل 100 اضافة 0
+
+330
+00:30:50,970 --> 00:30:57,310
+.8 YD وانتجة 600 ولا تكتفية يقل 0 لذا Y يقل نفس
+
+331
+00:30:57,310 --> 00:31:02,710
+المفهوم نفس البرنامج ولكن تكتفية يقل 0 في هذه
+
+332
+00:31:02,710 --> 00:31:07,530
+الحالة لذا يجب أن يكون Y يقل YD صح؟ لذلك دعونا
+
+333
+00:31:07,530 --> 00:31:10,430
+نذهب إلى هذا المثال
+
+334
+00:31:14,320 --> 00:31:17,440
+في هذا المثال، هذا هو السبب لإيقاف الميزة
+
+335
+00:31:17,440 --> 00:31:21,440
+التجارية، هذا هو C ، T تقاليد التجارة التجارية
+
+336
+00:31:21,440 --> 00:31:22,540
+التجارية التجارية التجارية التجارية التجارية
+
+337
+00:31:22,540 --> 00:31:23,580
+التجارية التجارية التجارية التجارية التجارية
+
+338
+00:31:23,580 --> 00:31:23,620
+التجارية التجارية التجارية التجارية التجارية
+
+339
+00:31:23,620 --> 00:31:24,060
+التجارية التجارية التجارية التجارية التجارية
+
+340
+00:31:24,060 --> 00:31:25,900
+التجارية التجارية التجارية التجارية التجارية
+
+341
+00:31:25,900 --> 00:31:26,620
+التجارية التجارية التجارية التجارية التجارية
+
+342
+00:31:26,620 --> 00:31:37,780
+التجارية التجارية التجارية التجارية التجارية
+
+343
+00:31:37,780 --> 00:31:47,260
+التجلذلك في الحالة الأولى C اضافة I اضافة G اضافة
+
+344
+00:31:47,260 --> 00:31:54,580
+اضافة اضافة اقوى C اضافة I اضافة G اضافة اقوى C
+
+345
+00:31:54,580 --> 00:31:57,800
+اضافة I اضافة G اضافة اقوى C اضافة I اضافة G اضافة
+
+346
+00:31:57,800 --> 00:32:02,120
+اقوى C
+
+347
+00:32:02,120 --> 00:32:04,800
+اضافة I اضافة G اضافة اقوى C اضافة I اضافة G اضافة
+
+348
+00:32:04,800 --> 00:32:06,940
+C اضافة I اضافة G اضافة G اضافة C اضافة I اضافة G
+
+349
+00:32:06,940 --> 00:32:07,220
+اضافة G اضافة C اضافة I اضافة G اضافة G اضافة C
+
+350
+00:32:07,220 --> 00:32:08,360
+اضافة G
+
+351
+00:32:11,660 --> 00:32:17,260
+700 اضافة 200 اضافة 100 اضافة 1000 اضافة صحيح؟
+
+352
+00:32:17,260 --> 00:32:22,840
+الثالث حالة 1000
+
+353
+00:32:22,840 --> 00:32:29,500
+اضافة 200 اضافة 1030 اضافة بالضبط 1300 اضافة و
+
+354
+00:32:29,500 --> 00:32:39,240
+بعدها 1600 اضافة لا 600 اضافة 1600 اضافة و الحالة
+
+355
+00:32:39,240 --> 00:32:49,180
+الأخيرة تقريباً 1900 رقم اثنان اثنان اثنان اثنان
+
+356
+00:32:49,180 --> 00:32:49,240
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+357
+00:32:49,240 --> 00:32:57,960
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+358
+00:32:57,960 --> 00:33:02,380
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+359
+00:33:02,380 --> 00:33:02,400
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+360
+00:33:02,400 --> 00:33:06,400
+اثنان
+
+361
+00:33:06,400 --> 00:33:13,280
+اثن ماذا يحدث عندما Y يكوين أسعار مجموعة؟ بالضبط في
+
+362
+00:33:13,280 --> 00:33:20,660
+1600، لذلك الانتاج يحدث عندما يكوين Y يكوين 1600
+
+363
+00:33:20,660 --> 00:33:25,880
+ومجموعة مجموعة يكوين نفس الشيء، لذلك انتاج مجموعة
+
+364
+00:33:25,880 --> 00:33:27,220
+أو أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+365
+00:33:27,220 --> 00:33:27,780
+أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+366
+00:33:27,780 --> 00:33:29,300
+أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+367
+00:33:29,300 --> 00:33:29,920
+أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+368
+00:33:29,920 --> 00:33:33,420
+أسعار مجموعة أو
+
+369
+00:33:33,420 --> 00:33:40,400
+أسعار مجمY إيقاظ 1200 Is there a positive
+
+370
+00:33:40,400 --> 00:33:44,360
+unplanned inventory change or negative؟ By how
+
+371
+00:33:44,360 --> 00:33:48,060
+much؟ So
+
+372
+00:33:48,060 --> 00:33:56,520
+let's write the question So at Y equals 1200 Is
+
+373
+00:33:56,520 --> 00:34:00,900
+there a negative or positive change in business
+
+374
+00:34:00,900 --> 00:34:06,300
+inventory or inventory change? Yes هو قيمة تغيير
+
+375
+00:34:06,300 --> 00:34:10,980
+البرنامج عن طريق تغيير البرنامج يقوم بالتغيير يقوم
+
+376
+00:34:10,980 --> 00:34:12,080
+بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير
+
+377
+00:34:12,080 --> 00:34:12,680
+يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم
+
+378
+00:34:12,680 --> 00:34:13,560
+بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير
+
+379
+00:34:13,560 --> 00:34:14,560
+يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم
+
+380
+00:34:14,560 --> 00:34:15,000
+بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير
+
+381
+00:34:15,000 --> 00:34:16,580
+يقوم بالتغيير يقوم بالتغير يقوم بالتغير يقوم
+
+382
+00:34:16,580 --> 00:34:25,440
+بالتغير يقوم بالتغير يقوم بالت 1300 يعني أقل من 100
+
+383
+00:34:25,440 --> 00:34:31,940
+في هذه الحالة الانفجار المخطط يتخلص أو يتخلص أو
+
+384
+00:34:31,940 --> 00:34:43,660
+يتخلص من 100 على ما يقل 800 هل هناك تندنسية للخروج
+
+385
+00:34:43,660 --> 00:34:54,030
+لتنفع أو لتتخلص؟ من كم؟ exactly by 800 مش not صح so
+
+386
+00:34:54,030 --> 00:35:00,910
+the question is suppose at y equals 400 billion
+
+387
+00:35:00,910 --> 00:35:04,710
+dollars or dollars is there a tendency for y to
+
+388
+00:35:04,710 --> 00:35:07,010
+increase or to decrease to reach the equilibrium
+
+389
+00:35:07,010 --> 00:35:12,730
+عشان نوصل التوازن عند 1600 why would or the
+
+390
+00:35:12,730 --> 00:35:15,370
+aggregate income or aggregate output must increase
+
+391
+00:35:15,370 --> 00:35:16,310
+by how much
+
+392
+00:35:23,160 --> 00:35:31,900
+1600 نقص 400 by 1200 صح طيب at 2000 or when y
+
+393
+00:35:31,900 --> 00:35:37,800
+equals 2000 million dollars exactly the y the
+
+394
+00:35:37,800 --> 00:35:42,140
+aggregate output must decline by 400 to reach the
+
+395
+00:35:42,140 --> 00:35:48,580
+equilibrium صح من الألفين لألف وستماية four hundred
+
+396
+00:35:48,580 --> 00:35:54,320
+to reach the equilibrium صح okay or at the
+
+397
+00:35:54,320 --> 00:35:56,660
+unagreed output level of eight hundred million
+
+398
+00:35:56,660 --> 00:36:00,520
+dollars a billion the disposable income equals
+
+399
+00:36:00,520 --> 00:36:07,680
+what how much Y minus T صح هي at eight hundred قدش
+
+400
+00:36:07,680 --> 00:36:10,800
+ال disposable income اللي هو ال Y دي equals Y
+
+401
+00:36:10,800 --> 00:36:20,970
+minus T so at eight here at 8 y equals 800 how much
+
+402
+00:36:20,970 --> 00:36:25,150
+is the disposable income؟ disposable income is YD
+
+403
+00:36:25,150 --> 00:36:32,670
+equals y minus t 800 minus 100 equals 700 this is
+
+404
+00:36:32,670 --> 00:36:35,630
+the disposable income طب how much is the saving in
+
+405
+00:36:35,630 --> 00:36:47,770
+this case؟ الحفظ يكون Y-C-T فالسؤال هو في Y يقل
+
+406
+00:36:47,770 --> 00:36:53,630
+2000 كم هو الحفظ؟
+
+407
+00:36:58,710 --> 00:37:03,430
+Value in Dollars How much is the saving? Saving
+
+408
+00:37:03,430 --> 00:37:13,510
+equals Y minus C minus T So S equals Y 2000 minus
+
+409
+00:37:13,510 --> 00:37:18,210
+The consumption in this case equals how much? 1600
+
+410
+00:37:18,210 --> 00:37:25,710
+minus T T equals 100 عن طريق الاستخدام يقوم
+
+411
+00:37:25,710 --> 00:37:31,590
+باستخدام الأسعار يقوم باستخدام الأسعار يقوم
+
+412
+00:37:31,590 --> 00:37:33,890
+باستخدام الأسعار يقوم باستخدام الأسعار يقوم
+
+413
+00:37:33,890 --> 00:37:36,610
+باستخدام الأسعار يقوم باستخدام الأسعار يقوم
+
+414
+00:37:36,610 --> 00:37:37,970
+باستخدام الأسعار يقوم باستخدام الأسعار يقوم
+
+415
+00:37:37,970 --> 00:37:39,670
+باستخدام الأسعار يقوم باستخدام الأسعار يقوم
+
+416
+00:37:39,670 --> 00:37:42,130
+باستخدام الأسعار يقوم باستخدام الأسعار يقوم
+
+417
+00:37:42,130 --> 00:37:44,630
+باستخدام الأسعار يقوم باستخدام الأسعار يقوم
+
+418
+00:37:44,630 --> 00:37:51,670
+باستخدام الأسعار يقوم باستخدام الأسعار يقوم باستof
+
+419
+00:37:51,670 --> 00:37:57,290
+income leakages equals how much leakages equals
+
+420
+00:37:57,290 --> 00:38:01,510
+how much عند aggregate income أو عند التوازن 
+
+421
+00:38:01,510 --> 00:38:04,930
+Leakages equals how much? As you know that the
+
+422
+00:38:04,930 --> 00:38:11,670
+Leakages equals S plus T, صح؟ At equilibrium the
+
+423
+00:38:11,670 --> 00:38:16,090
+Leakages leakages
+
+424
+00:38:19,550 --> 00:38:25,030
+اللي هو S plus T صح؟ و ال injections ايش؟ I plus G
+
+425
+00:38:25,030 --> 00:38:29,990
+مصبوح؟ صح؟ So at equilibrium و ال equilibrium عند
+
+426
+00:38:29,990 --> 00:38:36,790
+1600 S plus T equals كدهش؟ Taxes equals 100 صح؟ كدهش
+
+427
+00:38:36,790 --> 00:38:40,390
+ال saving؟ We have to calculate saving, saving at 
+
+428
+00:38:40,390 --> 00:38:40,990
+equilibrium
+
+429
+00:38:43,920 --> 00:38:50,080
+S Equals Y Minus C Minus T صح؟ So Saving Equals Y
+
+430
+00:38:50,080 --> 00:38:57,960
+is 1600 Minus C 1300
+
+431
+00:38:57,960 --> 00:39:07,200
+Minus 100 So The Saving Equals How Much? 200 Right؟
+
+432
+00:39:07,200 --> 00:39:13,990
+This Is The S So The Leakage Is Leakage Is equals S
+
+433
+00:39:13,990 --> 00:39:19,710
+plus T or equals S 200 plus taxes 1
+
+434
+00:39:19,710 --> 00:39:25,150
+hundred so equals three hundred billion dollars صح
+
+435
+00:39:25,150 --> 00:39:31,490
+طب كدهش ال injections I plus G so at equilibrium
+
+436
+00:39:31,490 --> 00:39:35,170
+طبعا at equilibrium leakages must equal injections
+
+437
+00:39:35,170 --> 00:39:42,710
+exactly so I 200 plus G 100 So at equilibrium
+
+438
+00:39:42,710 --> 00:39:48,350
+leakages equals injections صح؟ Injections صح؟ So
+
+439
+00:39:48,350 --> 00:39:54,070
+the injection is I plus G equals 200 plus 100
+
+440
+00:39:54,070 --> 00:40:03,290
+Right؟ Okay Let's go to this exercise
+
+441
+00:40:11,500 --> 00:40:18,320
+كما تشاهدين الـ C يقل .. او الاقتصاد الإيطالي يمكن
+
+442
+00:40:18,320 --> 00:40:25,720
+ان يكون مصمم من المقارنة او المقارنة C يقل 300 C
+
+443
+00:40:25,720 --> 00:40:34,100
+يقل 300 plus 0.8 YD، صحيح؟ ومقارنتة الحكومة يقل G
+
+444
+00:40:34,100 --> 00:40:41,360
+يقل 400 مليون دولار تي تاكسيأو 200 مليون دولار
+
+445
+00:40:41,360 --> 00:40:46,780
+وإستخدام المخطط يكون 200 مليون دولار.السؤال هو
+
+446
+00:40:46,780 --> 00:40:55,570
+أولا، مستوى الإيقال للإيقاع الإيطالي هو كم؟لذلك
+
+447
+00:40:55,570 --> 00:40:59,910
+يجب أن نقوم بالتخطيط للمستوى الإيقاليبيومي لجهة
+
+448
+00:40:59,910 --> 00:41:02,410
+الـ Aggregate Output في المستوى الإيقاليبيويمي كما
+
+449
+00:41:02,410 --> 00:41:05,130
+تعلمين Y يقوم بالتخطيط لجهة الـ Aggregate
+
+450
+00:41:05,130 --> 00:41:09,750
+Expenditure لذلك Y يقوم بالتخطيط لـ C Plus I Plus
+
+451
+00:41:09,750 --> 00:41:19,370
+G لذلك Y يقوم بالتخطيط لـ C 300 Plus 0.8 Y D Plus
+
+452
+00:41:19,370 --> 00:41:33,040
+I 200 plus g 400 right so y equals 300 plus 0.8
+
+453
+00:41:33,040 --> 00:41:41,300
+times yd is y minus t صح so y minus t is given the
+
+454
+00:41:41,300 --> 00:41:47,180
+tax the net tax is given so equals 200 plus 200
+
+455
+00:41:47,180 --> 00:41:57,490
+plus 400 صحSo Y equals 300 plus 200 plus 400
+
+456
+00:41:57,490 --> 00:42:09,930
+equals 900 plus 0.8Y minus 0.8 times 200 equals
+
+457
+00:42:09,930 --> 00:42:10,630
+160
+
+458
+00:42:13,290 --> 00:42:20,730
+مصبوح؟ So اعمل shifting هيك Y minus 0.8Y equals
+
+459
+00:42:20,730 --> 00:42:30,690
+900 minus 160 equals how much? 740 So this is one
+
+460
+00:42:30,690 --> 00:42:41,470
+0.2Y equals 740 So how much is Y? So Y equals
+
+461
+00:42:46,570 --> 00:42:56,350
+740 over 0.2 صح؟ So Y equals how much؟ That's it
+
+462
+00:42:56,350 --> 00:43:01,950
+B, the answer is B Right؟ How much is the
+
+463
+00:43:01,950 --> 00:43:05,230
+consumption in this case؟ Because that's a direct
+
+464
+00:43:05,230 --> 00:43:14,760
+substitution So C Yes أمسح هذا؟Okay, so calculate
+
+465
+00:43:14,760 --> 00:43:17,320
+the consumption, the aggregate consumption in this
+
+466
+00:43:17,320 --> 00:43:25,960
+case C equals 300 plus 0.8 times YD So, C equals
+
+467
+00:43:25,960 --> 00:43:31,660
+300 plus 0.8 times Y at equilibrium equals how
+
+468
+00:43:31,660 --> 00:43:44,270
+much? 3700 minus T, T equals how much? 200 so C
+
+469
+00:43:44,270 --> 00:43:56,150
+equals 300 plus 0.8 times 3700 minus 200 3500
+
+470
+00:43:56,150 --> 00:44:04,530
+so C equals 300 plus how much the 0.8 times اعمله
+
+471
+00:44:04,530 --> 00:44:09,890
+مع الاهلة شوفوا how much
+
+472
+00:44:11,690 --> 00:44:18,970
+Okay two thousand eight hundred so c equals three
+
+473
+00:44:18,970 --> 00:44:23,010
+hundred three thousand one hundred billion dollars
+
+474
+00:44:23,010 --> 00:44:28,790
+so So as you see here the consumption equals how
+
+475
+00:44:28,790 --> 00:44:32,670
+much three thousand one hundred so the answer is a
+
+476
+00:44:32,670 --> 00:44:35,210
+right يعطيكم العشري 
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/B1sxcr4enWA_postprocess.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/B1sxcr4enWA_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..c6e37b17df953aba8b0a291d9c83cd814beb2b9c
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/B1sxcr4enWA_postprocess.srt
@@ -0,0 +1,1904 @@
+1
+00:00:20,650 --> 00:00:23,990
+بسم الله الرحمن الرحيم اليوم ان شاء الله سنقوم
+
+2
+00:00:23,990 --> 00:00:27,310
+باختيار بعض التدريبات و بعض التدريبات الواقعية
+
+3
+00:00:27,310 --> 00:00:35,870
+مرتبطة بالقصة 4 و 5 قبل ان نكمل القصة 5 بشكل صحيح؟
+
+4
+00:00:35,870 --> 00:00:39,810
+لذلك لكي نتأكد أن كل شيء ماضي بشكل صحيح كل شيء
+
+5
+00:00:39,810 --> 00:00:43,190
+ماضي بشكل صحيح لذا دعونا ناخد التدريبات التالية
+
+6
+00:00:44,070 --> 00:00:49,690
+تجعلها أسهل تفهيم الدراسة كما تشاهد في هذا المثال
+
+7
+00:00:49,690 --> 00:00:55,230
+أو في هذا التعليق إذا كانت عملية استخدام C 100
+
+8
+00:00:55,230 --> 00:01:08,410
+plus 0.8Y و I 50 المسألة هي مستوى الميزاني هو كم؟
+
+9
+00:01:08,410 --> 00:01:14,740
+كما تعلمينإذا لم يكن هناك حكومة، فإن الانتجار يحدث
+
+10
+00:01:14,740 --> 00:01:20,260
+عندما Y يكوين أسعار الانتجار، فإن الانتجار يكوين
+
+11
+00:01:20,260 --> 00:01:24,460
+أسعار الانتجار وإذا لم يكن هناك حكومة، فإن أسعار
+
+12
+00:01:24,460 --> 00:01:30,000
+الانتجار يكوين كم؟ C بلس I، ففي الانتجار Y
+
+13
+00:01:37,140 --> 00:01:38,540
+YYYYYYYYYYYYYYYYYYY
+
+14
+00:01:49,250 --> 00:01:56,230
+-0.8y-0
+
+15
+00:01:56,230 --> 00:02:01,690
+.8y
+
+16
+00:02:01,690 --> 00:02:10,130
+-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y
+
+17
+00:02:10,130 --> 00:02:10,470
+-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y
+
+18
+00:02:10,470 --> 00:02:12,630
+-0.8y-0.8y-0.8
+
+19
+00:02:23,110 --> 00:02:28,550
+ماذا عن المستخدم في هذه الحالة؟ كم هو المستخدم؟
+
+20
+00:02:31,450 --> 00:02:36,850
+exactly yes yes yes aggregate expenditure equals c
+
+21
+00:02:36,850 --> 00:02:41,610
+plus i the aggregate income equals c plus s right
+
+22
+00:02:41,610 --> 00:02:46,430
+so as we mentioned that at equilibrium the
+
+23
+00:02:46,430 --> 00:02:49,390
+aggregate income equals aggregate expenditure
+
+24
+00:02:49,390 --> 00:02:52,550
+right or the aggregate output equals the aggregate
+
+25
+00:02:52,550 --> 00:02:58,470
+expenditureتخيل قيمة الانتجار أو الانتجار المجموعة
+
+26
+00:02:58,470 --> 00:03:05,070
+في الانتجار الانتجار الانتجار الانتجار الانتجار
+
+27
+00:03:05,070 --> 00:03:09,230
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+28
+00:03:09,230 --> 00:03:12,150
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+29
+00:03:12,150 --> 00:03:13,090
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+30
+00:03:13,090 --> 00:03:21,710
+الانتجار الانتجار الانتجار الانتجار الانتجار ال
+
+31
+00:03:25,220 --> 00:03:28,340
+هذا هو ايقاليبريم التخزين أو قيمة التخزين في
+
+32
+00:03:28,340 --> 00:03:36,580
+ايقاليبريم اذا C ايقال 100 plus 0.8 times 750 كم
+
+33
+00:03:36,580 --> 00:03:45,320
+كده كده كده كده كده كده كده كده كده كده كده كده
+
+34
+00:03:45,320 --> 00:03:45,380
+كده كده كده كده كده كده كده كده كده كده كده كده
+
+35
+00:03:45,380 --> 00:03:46,380
+كده كده كده كده كده كده كده كده كده كده كده كده
+
+36
+00:03:46,380 --> 00:03:50,780
+كده كده
+
+37
+00:03:50,780 --> 00:03:57,130
+كده كده كده كده كده كده كده كده كدSaving equals Y
+
+38
+00:03:57,130 --> 00:04:07,510
+minus C So it should be 700 What about the
+
+39
+00:04:07,510 --> 00:04:12,550
+aggregate saving? Saving equals Y minus C when
+
+40
+00:04:12,550 --> 00:04:17,270
+there is no government So S saving equals Y minus
+
+41
+00:04:17,270 --> 00:04:23,700
+Cالسعر يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+42
+00:04:23,700 --> 00:04:24,540
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+43
+00:04:24,540 --> 00:04:25,380
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+44
+00:04:25,380 --> 00:04:25,580
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+45
+00:04:25,580 --> 00:04:25,700
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+46
+00:04:25,700 --> 00:04:26,700
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+47
+00:04:26,700 --> 00:04:46,540
+باستخدام Y يقوم باستخدام Y
+
+48
+00:04:51,290 --> 00:05:01,230
+كما تشاهد، فإن عملي التخزين يقل 1500 plus 0.75Y I
+
+49
+00:05:01,230 --> 00:05:07,470
+يقل 500 مليون دولار فالسؤال هو إذا كان عملي
+
+50
+00:05:07,470 --> 00:05:11,190
+التخزين يقل عملي التخزين في مستوى نسخة نسخة نسخة
+
+51
+00:05:11,190 --> 00:05:15,750
+نسخة نسخة
+
+52
+00:05:17,420 --> 00:05:22,700
+السؤال هو إذا
+
+53
+00:05:22,700 --> 00:05:28,120
+S
+
+54
+00:05:28,120 --> 00:05:34,600
+إقل I، إذا S إقل I، إذا S إقل I، إذا S إقل I، إذا
+
+55
+00:05:34,600 --> 00:05:35,520
+S إقل I، إذا S إقل I، إذا S إقل I، إذا S إقل I،
+
+56
+00:05:35,520 --> 00:05:35,940
+إذا S إقل I، إذا S إقل I، إذا S إقل I، إذا S إقل
+
+57
+00:05:35,940 --> 00:05:36,880
+إذا S إقل I، إذا S إقل I، إذا S إقل I، إذا S إقل
+
+58
+00:05:36,880 --> 00:05:42,510
+I، إذا Swhen y equals aggregate expenditure C plus
+
+59
+00:05:42,510 --> 00:05:47,170
+S equals C plus I so deduction of C so S equals I
+
+60
+00:05:47,170 --> 00:05:51,270
+at equilibrium so the same we have to do the same
+
+61
+00:05:51,270 --> 00:05:54,790
+to derive the equilibrium aggregate output the
+
+62
+00:05:54,790 --> 00:05:57,950
+equilibrium aggregate output in this case equals C
+
+63
+00:05:57,950 --> 00:06:04,470
+plus I the same so in this case أمسح هذا
+
+64
+00:06:20,450 --> 00:06:25,710
+السؤال هو تخطيط الميزة التجاربية أو الميزة
+
+65
+00:06:25,710 --> 00:06:29,670
+التجاربية الاجتماعية عندما تخطيط الميزة التجاربية
+
+66
+00:06:29,670 --> 00:06:30,310
+أو الميزة التجاربية
+
+67
+00:06:34,070 --> 00:06:42,270
+يكون y يكون c plus i في الانتجار يكون y يكون 1500
+
+68
+00:06:42,270 --> 00:06:48,950
+plus 0.75 y plus 500 مليون دولار في الانتجار يكون
+
+69
+00:06:48,950 --> 00:06:58,670
+y يكون 2000 plus 0.75 y يكون y يكون 2000 plus 0.75
+
+70
+00:06:58,670 --> 00:07:08,100
+y يكونEquals 2000 So Zero Point Yes 25Y Equals
+
+71
+00:07:08,100 --> 00:07:15,660
+2000 So Y Equals 8000 Million Dollars That's It So
+
+72
+00:07:15,660 --> 00:07:21,720
+At Equilibrium The Aggregate Output Equals 8000
+
+73
+00:07:21,720 --> 00:07:24,380
+Million Dollars How Much Is The Consumption In
+
+74
+00:07:24,380 --> 00:07:27,200
+This Case Dark Substitution Of The Consumption
+
+75
+00:07:27,200 --> 00:07:34,550
+Function صحلتخطيط أو تخطيط استخدام المجموعة C يقل
+
+76
+00:07:34,550 --> 00:07:45,050
+كم؟ C يقل 1500 plus 0.75 times Y يقل 8000 مليون
+
+77
+00:07:45,050 --> 00:07:59,310
+دولار C يقل 1500 plus كم؟ هل أنت متأكد؟6000 مليون
+
+78
+00:07:59,310 --> 00:08:10,590
+دولار او 7500 مليون دولار او
+
+79
+00:08:10,590 --> 00:08:14,710
+7500 مليون دولار
+
+80
+00:08:17,160 --> 00:08:24,500
+-7500-500 يعني أن هذا هو المساعدة الأساسية أو
+
+81
+00:08:24,500 --> 00:08:25,800
+المساعدة الأساسية
+
+82
+00:08:30,970 --> 00:08:36,210
+نعم، نفس الفكرة، نفس البرنامج. لذلك، دعنا نذهب إلى
+
+83
+00:08:36,210 --> 00:08:40,510
+هذه الفيجورة أو هذا البرنامج. كما ترى، هذا هو
+
+84
+00:08:40,510 --> 00:08:44,570
+عملية المساعدة العضلية. A عملية المساعدة العضلية
+
+85
+00:08:44,570 --> 00:08:52,350
+يعني C plus I وهذا Y. يحدث الانعكاس عندما Y يعني
+
+86
+00:08:52,350 --> 00:08:55,370
+عملية المساعدة العضلية. هذا عملية المساعدة العضلية
+
+87
+00:08:55,370 --> 00:08:56,310
+Y.
+
+88
+00:08:58,410 --> 00:08:59,910
+وهذا Y.
+
+89
+00:09:03,470 --> 00:09:07,550
+الإيقاليبريام كما ترى يحدث عند Y إيقاليبريام
+
+90
+00:09:07,550 --> 00:09:13,790
+اتساقط افعالية اجرية ايه؟ اذا كم هو ال .. او كم هو
+
+91
+00:09:13,790 --> 00:09:15,910
+ال .. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه
+
+92
+00:09:15,910 --> 00:09:16,730
+.. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه ..
+
+93
+00:09:16,730 --> 00:09:17,050
+اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه
+
+94
+00:09:17,050 --> 00:09:18,570
+.. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه ..
+
+95
+00:09:18,570 --> 00:09:20,010
+.. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه ..
+
+96
+00:09:20,010 --> 00:09:23,690
+اه .. اه .. اه .. اه .. اه ..
+
+97
+00:09:28,380 --> 00:09:34,820
+derive the aggregate expenditure function
+
+98
+00:09:34,820 --> 00:09:39,700
+as you know that the aggregate expenditure
+
+99
+00:09:39,700 --> 00:09:43,020
+function includes the autonomous aggregate
+
+100
+00:09:43,020 --> 00:09:47,540
+expenditure plus the slope of the function times y
+
+101
+00:09:50,000 --> 00:09:54,140
+او او او او او او او او او او او او او او او او او
+
+102
+00:09:54,140 --> 00:09:55,340
+او او او او او او او او او او او او او او او او او
+
+103
+00:09:55,340 --> 00:10:01,440
+او او او او او او او او او او او او او او او او او
+
+104
+00:10:01,440 --> 00:10:03,480
+او او او او او او او او او او او او او او او او او
+
+105
+00:10:03,480 --> 00:10:08,300
+او او او او او
+
+106
+00:10:11,510 --> 00:10:16,770
+هذه المقارنة على هذه المقارنة لكتابة مقارنة
+
+107
+00:10:16,770 --> 00:10:18,290
+الهزيمة التي تستخدمها
+
+108
+00:10:22,790 --> 00:10:28,070
+-150 over 200 This is the marginal propensity to
+
+109
+00:10:28,070 --> 00:10:32,990
+consume, صح؟ So aggregate expenditure function in
+
+110
+00:10:32,990 --> 00:10:36,430
+this case equals the autonomous aggregate
+
+111
+00:10:36,430 --> 00:10:42,870
+expenditure which equals 150 plus the MBC times Y,
+
+112
+00:10:43,010 --> 00:10:48,090
+صح؟ MBC equals how much? MBC in this case equals
+
+113
+00:10:49,470 --> 00:10:51,670
+السلوب بالضبط سلوب عملية عملية عملية عملية عملية
+
+114
+00:10:51,670 --> 00:10:54,030
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+115
+00:10:54,030 --> 00:10:55,690
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+116
+00:10:55,690 --> 00:10:55,990
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+117
+00:10:55,990 --> 00:10:56,930
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+118
+00:10:56,930 --> 00:10:57,570
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+119
+00:10:57,570 --> 00:10:57,590
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+120
+00:10:57,590 --> 00:10:58,190
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+121
+00:10:58,190 --> 00:11:18,650
+عملية عمل
+
+122
+00:11:19,860 --> 00:11:25,360
+At equilibrium mathematically حسبولنا ال Y و ال
+
+123
+00:11:25,360 --> 00:11:25,960
+consumption
+
+124
+00:11:46,720 --> 00:12:00,760
+Y-0.25Y-0.25Yزي 0.75 Y يقل 150، فY يقل كم؟ 200،
+
+125
+00:12:00,760 --> 00:12:06,100
+بالضبط، يجب أن يكون 200، لأن الاتصال هو 200، كما
+
+126
+00:12:06,100 --> 00:12:11,580
+ترى، صحيح؟ ماذا
+
+127
+00:12:11,580 --> 00:12:16,970
+أخر؟calculate the investment multiplier or the
+
+128
+00:12:16,970 --> 00:12:19,950
+value of investment multiplier the question is
+
+129
+00:12:19,950 --> 00:12:25,390
+calculate the investment multiplier the investment
+
+130
+00:12:25,390 --> 00:12:29,130
+multiplier equals how much or what's what's the
+
+131
+00:12:29,130 --> 00:12:32,950
+formula of the investment multiplier one over
+
+132
+00:12:37,520 --> 00:12:42,320
+السؤال هو تخطيط المزيد من المستخدمين المستخدمين
+
+133
+00:12:42,320 --> 00:12:44,780
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+134
+00:12:44,780 --> 00:12:45,020
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+135
+00:12:45,020 --> 00:12:45,540
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+136
+00:12:45,540 --> 00:12:46,020
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+137
+00:12:46,020 --> 00:12:48,100
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+138
+00:12:48,100 --> 00:12:48,500
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+139
+00:12:48,500 --> 00:12:49,320
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+140
+00:12:49,320 --> 00:12:50,200
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+141
+00:12:50,200 --> 00:12:55,460
+المستخدمين المستخدمين المستخدمين
+
+142
+00:12:55,460 --> 00:13:00,330
+المستخدمينمع ذلك، الـ Investment Multiplier يقوم
+
+143
+00:13:00,330 --> 00:13:03,250
+بالتخلص من 1 على 1 مقارنة 1 مقارنة 1 مقارنة 1
+
+144
+00:13:03,250 --> 00:13:06,290
+مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1
+
+145
+00:13:06,290 --> 00:13:09,350
+مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1
+
+146
+00:13:09,350 --> 00:13:15,370
+مقارنة 1 مقارنة 1 مقارنة 1 مقارنة
+
+147
+00:13:20,410 --> 00:13:25,150
+1.33 مليون دولار، هذا يعني أنه إذا ارتكاب
+
+148
+00:13:25,150 --> 00:13:28,910
+الاستثمار او الاستثمار المخطط ارتكب 1 مليون دولار،
+
+149
+00:13:28,910 --> 00:13:30,550
+فإن نسبة الاستثمار المخطط أو الاستثمار المخطط
+
+150
+00:13:30,550 --> 00:13:39,710
+سترتكب 1.33 مليون دولار، صح؟ حسنا؟ طيب، اعتقد ان
+
+151
+00:13:39,710 --> 00:13:42,090
+الاستثمار المخطط ارتكب
+
+152
+00:13:46,320 --> 00:13:51,780
+50 مليون دولار المسألة هي .. اعتبار ان الاستثمار
+
+153
+00:13:51,780 --> 00:13:58,480
+المخطط يزيد من 50 مليون دولار كم هو قيمة التغيير
+
+154
+00:13:58,480 --> 00:14:01,740
+في الاختصار التجاربية او الاستثمار التجاربي يعني
+
+155
+00:14:01,740 --> 00:14:07,860
+اعتبار ان الاستثمار التجاربي يزيد من 50 مليون
+
+156
+00:14:07,860 --> 00:14:16,930
+دولار هذا دلتا I دلتا I يقل50 مليون دولار صح؟
+
+157
+00:14:16,930 --> 00:14:22,310
+السؤال هو تخطيط او نعم تخطيط التغيير في الانتجار
+
+158
+00:14:22,310 --> 00:14:27,910
+التجاري والتحكم في الانتجار التجاري الجديد على
+
+159
+00:14:27,910 --> 00:14:33,770
+الفيرمين أو على الفجر نفس الشيء نعم، لذلك كما
+
+160
+00:14:33,770 --> 00:14:40,730
+تعلمين أن دلتا Y عبر دلتا I اكتر واحد عبر MBS او
+
+161
+00:14:40,730 --> 00:14:47,390
+واحد مانوس MBC، لذلك دلتا Yمفروض ان دلتا اي مفروض
+
+162
+00:14:47,390 --> 00:15:03,970
+ان دلتا
+
+163
+00:15:03,970 --> 00:15:17,820
+اي مفروض ان دلتا ايمع 0.75 مرة مرة مرة مرة مرة مرة
+
+164
+00:15:17,820 --> 00:15:18,040
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+165
+00:15:18,040 --> 00:15:18,240
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+166
+00:15:18,240 --> 00:15:18,560
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+167
+00:15:18,560 --> 00:15:18,880
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+168
+00:15:18,880 --> 00:15:19,600
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+169
+00:15:19,600 --> 00:15:20,480
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+170
+00:15:20,480 --> 00:15:24,380
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+171
+00:15:24,380 --> 00:15:31,870
+مرة مرة مرة مرة مرة مرة مرة م66.6% هذا ما هو
+
+172
+00:15:31,870 --> 00:15:34,830
+التغيير في الميزة التجارية أو الميزة التجارية
+
+173
+00:15:34,830 --> 00:15:40,310
+الخاصة بكفة ميزة التجارة الخاصة بكفة ميزة التجارة
+
+174
+00:15:40,310 --> 00:15:41,570
+الخاصة بكفة ميزة التجارة الخاصة بكفة ميزة التجارة
+
+175
+00:15:41,570 --> 00:15:47,110
+الخاصة بكفة ميزة التجارة الخاصة بكفة ميزة التجارة
+
+176
+00:15:47,110 --> 00:15:47,190
+الخاصة بكفة M
+
+177
+00:15:58,320 --> 00:16:01,980
+266.6 مليار دولار ، وهذا هو الانقلاب الجديد ، لذلك
+
+178
+00:16:01,980 --> 00:16:07,180
+نتوقع أن يكون هناك انقلاب جديد في هذا النقطة ،
+
+179
+00:16:07,180 --> 00:16:13,960
+لذلك لدينا تغيير كامل أو تغيير أعلى من عملية
+
+180
+00:16:13,960 --> 00:16:18,520
+التجارب التجاربية ، لذلك هذا هو تجارب التجارب
+
+181
+00:16:18,520 --> 00:16:21,760
+التجاربية 2 C plus I plus Delta I
+
+182
+00:16:25,870 --> 00:16:31,170
+and this is the new equilibrium output or income
+
+183
+00:16:31,170 --> 00:16:39,310
+yes exactly 66.6 is the increasing of aggregate
+
+184
+00:16:39,310 --> 00:16:41,890
+income or the increasing of aggregate output
+
+185
+00:17:02,420 --> 00:17:12,540
+القيمة المرتبطة تغيير
+
+186
+00:17:12,540 --> 00:17:23,440
+ايقاليبرام اكسبورت حسنا
+
+187
+00:17:23,440 --> 00:17:26,800
+دعونا
+
+188
+00:17:26,800 --> 00:17:28,420
+نأخذ التالي
+
+189
+00:17:36,040 --> 00:17:38,960
+كما ترى لدينا المعلومات التالتة مباشرة مباشرة
+
+190
+00:17:38,960 --> 00:17:44,280
+مباشرة مباشرة مباشرة
+
+191
+00:17:44,280 --> 00:17:47,060
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+192
+00:17:47,060 --> 00:17:48,340
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+193
+00:17:48,340 --> 00:17:48,620
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+194
+00:17:48,620 --> 00:17:48,840
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+195
+00:17:48,840 --> 00:17:50,320
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+196
+00:17:50,320 --> 00:18:00,540
+مباشرة مباشرة مباشرة مباشرة مباشرة
+
+197
+00:18:01,940 --> 00:18:10,300
+مبسفة مبسفة مبسفة مبسفة مبسفة مبسفة
+
+198
+00:18:10,300 --> 00:18:16,300
+مبسفة مبسفة مبسفة مبسفة
+
+199
+00:18:16,300 --> 00:18:23,220
+مبسفة مبسفة مبسفة مبسفة
+
+200
+00:18:23,220 --> 00:18:30,300
+مبسفة مبسفة مبسفة مبسفة مبسفة مبسفة مبسفة مبسفة
+
+201
+00:18:33,100 --> 00:18:36,020
+الانبعاد الوضعي يزيد من نفس المقاومة 50 مليون
+
+202
+00:18:36,020 --> 00:18:40,760
+دولار اتخاذ التغيير في الميزة التجاربية نفس الفكرة
+
+203
+00:18:40,760 --> 00:18:47,660
+لذا دلتا Y على دلتا I اكتر من 1 على MPS لذلك دلتا
+
+204
+00:18:47,660 --> 00:18:53,560
+Y على دلتا I 50 اكتر من 1 على 0.70
+
+205
+00:18:55,920 --> 00:19:05,020
+دلتا Y اكتر من 50 اكتر من 0.70 اكتر من 71
+
+206
+00:19:05,020 --> 00:19:09,820
+.4
+
+207
+00:19:15,040 --> 00:19:18,840
+بالتالي، الانقراز كما ترى، الانقراز من قيمة الـ
+
+208
+00:19:18,840 --> 00:19:23,240
+MBC الـ Margin Propensity Consumed يتسبب في انقراز
+
+209
+00:19:23,240 --> 00:19:27,020
+القيمة أو التغيير في الميزة التجارية أو الميزة
+
+210
+00:19:27,020 --> 00:19:30,940
+التجارية الصح؟ في المرة الأولى، الـ MBC في الحالة
+
+211
+00:19:30,940 --> 00:19:35,700
+السابقة، عندما ميزة الـ MBC كانت 0.25 ميزة كم هي
+
+212
+00:19:35,700 --> 00:19:39,540
+انقراز الميزة التجارية؟ 66.6 ميزة تجارية، صح؟ لكن
+
+213
+00:19:39,540 --> 00:19:44,080
+الآن، انقراز MBC يتسبب في انقراز الميزة التجارية
+
+214
+00:19:49,000 --> 00:19:55,980
+الشيء نفسه ..الشيء نفسه ..الشيء نفسه
+
+215
+00:19:55,980 --> 00:19:59,620
+..الشيء نفسه
+
+216
+00:19:59,620 --> 00:20:01,840
+..الشيء نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء
+
+217
+00:20:01,840 --> 00:20:03,560
+نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء نفسه
+
+218
+00:20:03,560 --> 00:20:03,900
+..الشيء نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء
+
+219
+00:20:03,900 --> 00:20:04,080
+..الشيء نفسه ..الشيء نفسه ..الشيء نفسه ..
+
+220
+00:20:12,870 --> 00:20:15,990
+في السابق .. نعم .. نعم .. نعم .. نعم .. في السابق
+
+221
+00:20:15,990 --> 00:20:26,230
+عندما MBC كانت 0.25 MBS 0.75 .. الأن عندما MBC أقل
+
+222
+00:20:26,230 --> 00:20:37,950
+0.30 MBS أقل 0.70 .. هذا هو .. حسنا؟ لا .. حسنا ..
+
+223
+00:20:37,950 --> 00:20:41,630
+MBC aggregate equilibrium
+
+224
+00:20:43,690 --> 00:20:49,470
+حسنًا دعونا نذهب إلى هذا المثال السؤال
+
+225
+00:20:49,470 --> 00:20:57,110
+هو اعتمد أنه لا يوجد حكومة أو مجتمع غير مجتمع لذلك
+
+226
+00:20:57,110 --> 00:21:03,530
+لا يوجد حكومة ونعمل تحت اقتصاد قريب إذا
+
+227
+00:21:03,530 --> 00:21:07,870
+كتابة الـ Multiplier هو او يقل 10 كتابة ال
+
+228
+00:21:07,870 --> 00:21:09,610
+Multiplier
+
+229
+00:21:13,220 --> 00:21:18,180
+10 مليون دولار تقريبًا 10 مليون دولار تقريبًا
+
+230
+00:21:18,180 --> 00:21:18,960
+تقريبًا 10 مليون دولار تقريبًا 10 مليون دولار
+
+231
+00:21:18,960 --> 00:21:22,120
+تقريبًا 10 مليون دولار تقريبًا 10 مليون دولار
+
+232
+00:21:22,120 --> 00:21:24,920
+تقريبًا 10 مليون دولار تقريبًا 10 مليون دولار
+
+233
+00:21:24,920 --> 00:21:28,660
+تقريبًا 10 مليون دولار تقريبًا 10 مليون دولار
+
+234
+00:21:28,660 --> 00:21:35,440
+تقريبًا 10 مليون دولار تقريبًا 10
+
+235
+00:21:35,440 --> 00:21:42,020
+مليون دولار تقريبًاالسؤال هو تخطيط التغيير في الـ
+
+236
+00:21:42,020 --> 00:21:44,060
+aggregate output أو الاتجار التجاري أو الاتجار
+
+237
+00:21:44,060 --> 00:21:45,520
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+238
+00:21:45,520 --> 00:21:48,720
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+239
+00:21:48,720 --> 00:21:50,440
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+240
+00:21:50,440 --> 00:21:53,000
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+241
+00:21:53,000 --> 00:21:54,400
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+242
+00:21:54,400 --> 00:21:55,180
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+243
+00:21:55,180 --> 00:21:55,580
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+244
+00:21:55,580 --> 00:21:58,160
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+245
+00:21:58,160 --> 00:22:04,640
+التجاري أو
+
+246
+00:22:04,640 --> 00:22:11,570
+الاتجار التجصح or to ignore this part so
+
+247
+00:22:11,570 --> 00:22:16,710
+multiplier 10 equals delta y over 10 so delta y
+
+248
+00:22:16,710 --> 00:22:20,530
+equals positive this is positive positive one
+
+249
+00:22:20,530 --> 00:22:23,650
+hundred so we expect that the aggregate output
+
+250
+00:22:23,650 --> 00:22:27,610
+would increase by one hundred billion dollars
+
+251
+00:22:27,610 --> 00:22:34,750
+right yes ربيعبس الواحد على واحد مانس MBC والله
+
+252
+00:22:34,750 --> 00:22:38,710
+عندي .. ال one .. the multiplier equals one over
+
+253
+00:22:38,710 --> 00:22:43,330
+.. one minus MBC, so one minus MBC is MPS حسب
+
+254
+00:22:43,330 --> 00:22:45,470
+الموضوع .. حسب الموضوع .. yes it depends .. yes
+
+255
+00:22:45,470 --> 00:22:53,110
+exactly طيب and this .. and this exercise what do
+
+256
+00:22:53,110 --> 00:22:59,380
+you seeلسنا لدينا حكومة وليس لدينا عالم خارق إذا
+
+257
+00:22:59,380 --> 00:23:05,740
+كان مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2 مبيعات
+
+258
+00:23:05,740 --> 00:23:08,240
+الـ MBS 0.2 مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2
+
+259
+00:23:08,240 --> 00:23:08,560
+مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2 مبيعات الـ
+
+260
+00:23:08,560 --> 00:23:10,320
+MBS 0.2 مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2
+
+261
+00:23:10,320 --> 00:23:12,440
+مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2 مبيعات الـ
+
+262
+00:23:12,440 --> 00:23:17,550
+MBS 0.2 مبيلذلك في هذه الحالة بيكسل بيكسل بيكسل
+
+263
+00:23:17,550 --> 00:23:18,150
+بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل
+
+264
+00:23:18,150 --> 00:23:21,670
+بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل
+
+265
+00:23:21,670 --> 00:23:30,750
+بيكسل بيكسل
+
+266
+00:23:31,340 --> 00:23:36,840
+عشان تعرف ان دلتا Y عشان دلتا I اكوال 1 عشان MBS
+
+267
+00:23:36,840 --> 00:23:43,320
+او 1 مانوس MBC دلتا Y عشان مانوس مانوس مانوس مانوس
+
+268
+00:23:43,320 --> 00:23:45,680
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+269
+00:23:45,680 --> 00:23:47,100
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+270
+00:23:47,100 --> 00:23:48,820
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+271
+00:23:48,820 --> 00:23:48,860
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+272
+00:23:48,860 --> 00:24:00,300
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مان
+
+273
+00:24:02,340 --> 00:24:10,340
+so sorry no to decrease pie yes yes so we expect
+
+274
+00:24:10,340 --> 00:24:14,080
+that we have a decrease in aggregate output by 200
+
+275
+00:24:14,080 --> 00:24:20,400
+million درهز sorry جايين لل governmentلا لسنا
+
+276
+00:24:20,400 --> 00:24:25,120
+نتكلم عن الحكومة، لسنا لدينا حكومة هنا، حسنا؟
+
+277
+00:24:25,120 --> 00:24:31,500
+حسنا، دعنا نذهب و نأخذ أو نأخذ بعض التعليمات لقصة
+
+278
+00:24:31,500 --> 00:24:37,060
+5 عندما نضيف الحكومة و مستخدم الـ aggregate، حسنا؟
+
+279
+00:24:43,280 --> 00:24:47,700
+كما تشاهد في هذا المثال، عملي الـ Pell هو 1000$
+
+280
+00:24:47,700 --> 00:24:54,080
+وعقله الـ net taxes هي 35350$ وعقله الـ disposable
+
+281
+00:24:54,080 --> 00:24:59,740
+income هو كم؟ عملي الـ disposable income هو YD يقل
+
+282
+00:24:59,740 --> 00:25:10,440
+Y-T لذلك YD يقل Y1000-350 يقل 650
+
+283
+00:25:13,150 --> 00:25:19,170
+right this is the first بلاش ييجي زيي و دي يجي
+
+284
+00:25:19,170 --> 00:25:29,410
+أصعب علمك الأصعب هنا عشان ما yes exactly طيب
+
+285
+00:25:29,410 --> 00:25:37,040
+in this example in 2007المدينة كامفيل قمت بتجميع
+
+286
+00:25:37,040 --> 00:25:45,600
+500 ألف دولار من التجارب التجارب تي اكواس 500 ألف
+
+287
+00:25:45,600 --> 00:25:47,320
+مليون دولار او دولار
+
+288
+00:26:03,700 --> 00:26:10,000
+We have a deficit because the taxes gained
+
+289
+00:26:10,000 --> 00:26:13,660
+or received is larger than the government spending
+
+290
+00:26:13,660 --> 00:26:17,880
+So we have a surplus by how much the difference
+
+291
+00:26:17,880 --> 00:26:22,440
+between G and T صح؟ مين أكبر؟ الإنفاق ولا الضريب
+
+292
+00:26:22,440 --> 00:26:25,800
+اللي جمعناها؟ مجمعين ضريب، لذا we have a surplus
+
+293
+00:26:25,800 --> 00:26:28,820
+by fifty thousand dollars
+
+294
+00:26:34,100 --> 00:26:43,000
+حسنًا دعونا نذهب إلى هذا المثال أو التعليم كما
+
+295
+00:26:43,000 --> 00:26:51,380
+ترى عملية استخدام المجموعة هي C يكوين 100 plus 0
+
+296
+00:26:51,380 --> 00:27:01,320
+.6YD ماذا أخر؟ المال Y يكوين 1000 وY يكوين 1000
+
+297
+00:27:01,320 --> 00:27:13,250
+دولاروالدفع الوضعي هو T يقل 300$ تقل كم؟ YD او
+
+298
+00:27:13,250 --> 00:27:21,830
+يمكننا استخدام الفرمولة C يقل 100 plus 0.6 YD YD
+
+299
+00:27:21,830 --> 00:27:31,460
+يقل Y minus T تغيير YD يقل Y minus Tyes exactly so
+
+300
+00:27:31,460 --> 00:27:35,980
+c equals one hundred plus zero point six times y
+
+301
+00:27:35,980 --> 00:27:42,020
+minus the taxes three three hundred right so what
+
+302
+00:27:42,020 --> 00:27:46,400
+do you see so c equals one hundred so y is given
+
+303
+00:27:46,400 --> 00:27:52,240
+exactly sorry yes y is given one thousand dollars
+
+304
+00:27:53,050 --> 00:28:02,270
+So C equals 100 plus 0.6 times 700 So C equals 100
+
+305
+00:28:02,270 --> 00:28:06,310
+plus 420
+
+306
+00:28:06,310 --> 00:28:15,070
+So C equals 520 Right Is
+
+307
+00:28:15,070 --> 00:28:25,270
+it clear طيب How much is the savingبالضبط كما
+
+308
+00:28:25,270 --> 00:28:29,210
+تعلمين إذا كان لدينا حكومة إذا كان هناك حكومة
+
+309
+00:28:29,210 --> 00:28:38,130
+يكوين C بلس S بلس T لأن جزء من حصتك يذهب للعيارات
+
+310
+00:28:38,130 --> 00:28:44,570
+لذلك لكي تتخيل حفظ في هذه الحالة حفظ يكوين Y minus
+
+311
+00:28:44,570 --> 00:28:53,960
+T minus C أو YD minus CSo CS saving equals YD
+
+312
+00:28:53,960 --> 00:29:01,640
+minus T minus C Or Y minus T minus C That's it So
+
+313
+00:29:01,640 --> 00:29:13,040
+S equals Y equals 1000 minus T taxes 300 minus C
+
+314
+00:29:13,040 --> 00:29:15,920
+520 صح
+
+315
+00:29:19,100 --> 00:29:22,380
+520 مقارنة بمقارنة مقارنة مقارنة مقارنة مقارنة
+
+316
+00:29:22,380 --> 00:29:23,780
+مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة
+
+317
+00:29:23,780 --> 00:29:33,800
+مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة
+
+318
+00:29:33,800 --> 00:29:45,160
+مقارنة
+
+319
+00:29:47,010 --> 00:29:51,550
+ولكن هنا يجب أن يكون مرتبط بـ yd بالضبط، لذلك
+
+320
+00:29:51,550 --> 00:29:57,150
+الاختيار في هذه الحالة يقل a plus b times yd وليس
+
+321
+00:29:57,150 --> 00:30:04,960
+yأو مانوس اي بلس اكي بلس وان مانوس بي مبس مبس مبس
+
+322
+00:30:04,960 --> 00:30:08,660
+مبس وي دي مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+323
+00:30:08,660 --> 00:30:08,680
+مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+324
+00:30:08,680 --> 00:30:09,860
+مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+325
+00:30:09,860 --> 00:30:13,360
+مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+326
+00:30:13,360 --> 00:30:26,840
+مبس مبس مبس مب
+
+327
+00:30:27,070 --> 00:30:36,350
+-100 plus 40yd صح the same so let's go to another
+
+328
+00:30:36,350 --> 00:30:38,590
+exercise or example
+
+329
+00:30:45,650 --> 00:30:50,970
+هنا لدينا عملية استخدام المجتمع C يقل 100 اضافة 0
+
+330
+00:30:50,970 --> 00:30:57,310
+.8 YD وانتجة 600 ولا تكتفية يقل 0 لذا Y يقل نفس
+
+331
+00:30:57,310 --> 00:31:02,710
+المفهوم نفس البرنامج ولكن تكتفية يقل 0 في هذه
+
+332
+00:31:02,710 --> 00:31:07,530
+الحالة لذا يجب أن يكون Y يقل YD صح؟ لذلك دعونا
+
+333
+00:31:07,530 --> 00:31:10,430
+نذهب إلى هذا المثال
+
+334
+00:31:14,320 --> 00:31:17,440
+في هذا المثال، هذا هو السبب لإيقاف الميزة
+
+335
+00:31:17,440 --> 00:31:21,440
+التجارية، هذا هو C ، T تقاليد التجارة التجارية
+
+336
+00:31:21,440 --> 00:31:22,540
+التجارية التجارية التجارية التجارية التجارية
+
+337
+00:31:22,540 --> 00:31:23,580
+التجارية التجارية التجارية التجارية التجارية
+
+338
+00:31:23,580 --> 00:31:23,620
+التجارية التجارية التجارية التجارية التجارية
+
+339
+00:31:23,620 --> 00:31:24,060
+التجارية التجارية التجارية التجارية التجارية
+
+340
+00:31:24,060 --> 00:31:25,900
+التجارية التجارية التجارية التجارية التجارية
+
+341
+00:31:25,900 --> 00:31:26,620
+التجارية التجارية التجارية التجارية التجارية
+
+342
+00:31:26,620 --> 00:31:37,780
+التجارية التجارية التجارية التجارية التجارية
+
+343
+00:31:37,780 --> 00:31:47,260
+التجلذلك في الحالة الأولى C اضافة I اضافة G اضافة
+
+344
+00:31:47,260 --> 00:31:54,580
+اضافة اضافة اقوى C اضافة I اضافة G اضافة اقوى C
+
+345
+00:31:54,580 --> 00:31:57,800
+اضافة I اضافة G اضافة اقوى C اضافة I اضافة G اضافة
+
+346
+00:31:57,800 --> 00:32:02,120
+اقوى C
+
+347
+00:32:02,120 --> 00:32:04,800
+اضافة I اضافة G اضافة اقوى C اضافة I اضافة G اضافة
+
+348
+00:32:04,800 --> 00:32:06,940
+C اضافة I اضافة G اضافة G اضافة C اضافة I اضافة G
+
+349
+00:32:06,940 --> 00:32:07,220
+اضافة G اضافة C اضافة I اضافة G اضافة G اضافة C
+
+350
+00:32:07,220 --> 00:32:08,360
+اضافة G
+
+351
+00:32:11,660 --> 00:32:17,260
+700 اضافة 200 اضافة 100 اضافة 1000 اضافة صحيح؟
+
+352
+00:32:17,260 --> 00:32:22,840
+الثالث حالة 1000
+
+353
+00:32:22,840 --> 00:32:29,500
+اضافة 200 اضافة 1030 اضافة بالضبط 1300 اضافة و
+
+354
+00:32:29,500 --> 00:32:39,240
+بعدها 1600 اضافة لا 600 اضافة 1600 اضافة و الحالة
+
+355
+00:32:39,240 --> 00:32:49,180
+الأخيرةتقريبا 1900 رقم اثنان اثنان اثنان اثنان
+
+356
+00:32:49,180 --> 00:32:49,240
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+357
+00:32:49,240 --> 00:32:57,960
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+358
+00:32:57,960 --> 00:33:02,380
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+359
+00:33:02,380 --> 00:33:02,400
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+360
+00:33:02,400 --> 00:33:06,400
+اثنان
+
+361
+00:33:06,400 --> 00:33:13,280
+اثنماذا يحدث عندما Y يكوين أسعار مجموعة؟ بالضبط في
+
+362
+00:33:13,280 --> 00:33:20,660
+1600 ، لذلك الانتجار يحدث عندما يكوين Y يكوين 1600
+
+363
+00:33:20,660 --> 00:33:25,880
+ومجموعة مجموعة يكوين نفس الشيء، لذلك انتجار مجموعة
+
+364
+00:33:25,880 --> 00:33:27,220
+أو أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+365
+00:33:27,220 --> 00:33:27,780
+أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+366
+00:33:27,780 --> 00:33:29,300
+أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+367
+00:33:29,300 --> 00:33:29,920
+أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+368
+00:33:29,920 --> 00:33:33,420
+أسعار مجموعة أو
+
+369
+00:33:33,420 --> 00:33:40,400
+أسعار مجمY إيقاظ 1200 Is there a positive
+
+370
+00:33:40,400 --> 00:33:44,360
+unplanned inventory change or negative؟ By how
+
+371
+00:33:44,360 --> 00:33:48,060
+much؟ So
+
+372
+00:33:48,060 --> 00:33:56,520
+let's write the question So at Y equals 1200 Is
+
+373
+00:33:56,520 --> 00:34:00,900
+there a negative or positive change in business
+
+374
+00:34:00,900 --> 00:34:06,300
+inventory or inventory change? Yesهو قيمة تغيير
+
+375
+00:34:06,300 --> 00:34:10,980
+البرنامج عن طريق تغيير البرنامج يقوم بالتغيير يقوم
+
+376
+00:34:10,980 --> 00:34:12,080
+بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير
+
+377
+00:34:12,080 --> 00:34:12,680
+يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم
+
+378
+00:34:12,680 --> 00:34:13,560
+بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير
+
+379
+00:34:13,560 --> 00:34:14,560
+يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم
+
+380
+00:34:14,560 --> 00:34:15,000
+بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير
+
+381
+00:34:15,000 --> 00:34:16,580
+يقوم بالتغيير يقوم بالتغير يقوم بالتغير يقوم
+
+382
+00:34:16,580 --> 00:34:25,440
+بالتغير يقوم بالتغير يقوم بالت1300 يعني أقل من 100
+
+383
+00:34:25,440 --> 00:34:31,940
+في هذه الحالة الانفجار المخطط يتخلص أو يتخلص أو
+
+384
+00:34:31,940 --> 00:34:43,660
+يتخلص من 100 على ما يقل 800 هل هناك تندنسية للخروج
+
+385
+00:34:43,660 --> 00:34:54,030
+لتنفع أو لتتخلص؟ من كم؟exactly by 800 مش not صح so
+
+386
+00:34:54,030 --> 00:35:00,910
+the question is suppose at y equals 400 billion
+
+387
+00:35:00,910 --> 00:35:04,710
+dollars or dollars is there a tendency for y to
+
+388
+00:35:04,710 --> 00:35:07,010
+increase or to decrease to reach the equilibrium
+
+389
+00:35:07,010 --> 00:35:12,730
+عشان نوصل التوازن عند 1600 why would or the
+
+390
+00:35:12,730 --> 00:35:15,370
+aggregate income or aggregate output must increase
+
+391
+00:35:15,370 --> 00:35:16,310
+by how much
+
+392
+00:35:23,160 --> 00:35:31,900
+1600 نقص 400 by 1200 صح طيب at 2000 or when y
+
+393
+00:35:31,900 --> 00:35:37,800
+equals 2000 million dollars exactly the y the
+
+394
+00:35:37,800 --> 00:35:42,140
+aggregate output must decline by 400 to reach the
+
+395
+00:35:42,140 --> 00:35:48,580
+equilibrium صحلا من الفين لألف ستمية four hundred
+
+396
+00:35:48,580 --> 00:35:54,320
+to reach the equilibrium صح okay or at the
+
+397
+00:35:54,320 --> 00:35:56,660
+unagreed output level of eight hundred million
+
+398
+00:35:56,660 --> 00:36:00,520
+dollars a billion the disposable income equals
+
+399
+00:36:00,520 --> 00:36:07,680
+what how much Y minus T صح هي at eight hundred قدش
+
+400
+00:36:07,680 --> 00:36:10,800
+ال disposable income اللي هو ال Y دي equals Y
+
+401
+00:36:10,800 --> 00:36:20,970
+minus T so at eight hereAt 8 y equals 800 how much
+
+402
+00:36:20,970 --> 00:36:25,150
+is the disposable income؟ disposable income is yd
+
+403
+00:36:25,150 --> 00:36:32,670
+equals y minus t 800 minus 100 equals 700 this is
+
+404
+00:36:32,670 --> 00:36:35,630
+the disposable income طب how much is the saving in
+
+405
+00:36:35,630 --> 00:36:47,770
+this case؟الحفظ يكون y-c-t فالسؤال هو في y يقل
+
+406
+00:36:47,770 --> 00:36:53,630
+2000 كم هو الحفظ؟
+
+407
+00:36:58,710 --> 00:37:03,430
+Value in Dollars How much is the saving? Saving
+
+408
+00:37:03,430 --> 00:37:13,510
+equals Y minus C minus T So S equals Y 2000 minus
+
+409
+00:37:13,510 --> 00:37:18,210
+The consumption in this case equals how much? 1600
+
+410
+00:37:18,210 --> 00:37:25,710
+minus T T equals 100عن طريق الاستخدام يقوم
+
+411
+00:37:25,710 --> 00:37:31,590
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+412
+00:37:31,590 --> 00:37:33,890
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+413
+00:37:33,890 --> 00:37:36,610
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+414
+00:37:36,610 --> 00:37:37,970
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+415
+00:37:37,970 --> 00:37:39,670
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+416
+00:37:39,670 --> 00:37:42,130
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+417
+00:37:42,130 --> 00:37:44,630
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+418
+00:37:44,630 --> 00:37:51,670
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم باستof
+
+419
+00:37:51,670 --> 00:37:57,290
+income leakages equals how much leakages equals
+
+420
+00:37:57,290 --> 00:38:01,510
+how much عند aggregate income او عند التوازن
+
+421
+00:38:01,510 --> 00:38:04,930
+leakages equals how much as you know that the
+
+422
+00:38:04,930 --> 00:38:11,670
+leakages equals s plus t صح at equilibrium the
+
+423
+00:38:11,670 --> 00:38:16,090
+leakages leakages
+
+424
+00:38:19,550 --> 00:38:25,030
+اللي هو S plus T صح؟ و ال injections ايش؟ I plus G
+
+425
+00:38:25,030 --> 00:38:29,990
+مصبوح؟ صح؟ So at equilibrium و ال equilibrium عند
+
+426
+00:38:29,990 --> 00:38:36,790
+1600 S plus T equals كدهش؟ Tax equals 100 صح؟ كدهش
+
+427
+00:38:36,790 --> 00:38:40,390
+ال saving؟ We have to calculate saving، saving at
+
+428
+00:38:40,390 --> 00:38:40,990
+equilibrium
+
+429
+00:38:43,920 --> 00:38:50,080
+S Equals Y Minus C Minus T صح؟ So Saving Equals Y
+
+430
+00:38:50,080 --> 00:38:57,960
+Is 1600 Minus C 1300
+
+431
+00:38:57,960 --> 00:39:07,200
+Minus 100 So The Saving Equals How Much 200 Right؟
+
+432
+00:39:07,200 --> 00:39:13,990
+This Is The S So The Leakage Is Leakage Isequals S
+
+433
+00:39:13,990 --> 00:39:19,710
+plus T or equals S two hundred plus taxes one
+
+434
+00:39:19,710 --> 00:39:25,150
+hundred so equals three hundred billion dollars صح
+
+435
+00:39:25,150 --> 00:39:31,490
+طب كدهش ال injections I plus G so at equilibrium
+
+436
+00:39:31,490 --> 00:39:35,170
+طبعا at equilibrium leakages must equal injections
+
+437
+00:39:35,170 --> 00:39:42,710
+exactly so I200 plus G 100 So at equilibrium
+
+438
+00:39:42,710 --> 00:39:48,350
+leakages equals injections صح؟ Injections صح؟ So
+
+439
+00:39:48,350 --> 00:39:54,070
+the injection is I plus G equals 200 plus 100
+
+440
+00:39:54,070 --> 00:40:03,290
+Right؟ Okay Let's go to this exercise
+
+441
+00:40:11,500 --> 00:40:18,320
+كما تشاهدين الـ C يقل .. او الاقتصاد الإيطالي يمكن
+
+442
+00:40:18,320 --> 00:40:25,720
+ان يكون مصمم من المقارنة او المقارنة C يقل 300 C
+
+443
+00:40:25,720 --> 00:40:34,100
+يقل 300 plus 0.8 YD، صحيح؟ ومقارنتة الحكومة يقل G
+
+444
+00:40:34,100 --> 00:40:41,360
+يقل 400 مليون دولار تي تاكسيأو 200 مليون دولار
+
+445
+00:40:41,360 --> 00:40:46,780
+وإستخدام المخطط يكون 200 مليون دولار.السؤال هو
+
+446
+00:40:46,780 --> 00:40:55,570
+أولا، مستوى الإيقال للإيقاع الإيطالي هو كم؟لذلك
+
+447
+00:40:55,570 --> 00:40:59,910
+يجب أن نقوم بالتخطيط للمستوى الإيقاليبيومي لجهة
+
+448
+00:40:59,910 --> 00:41:02,410
+الـ Aggregate Output في المستوى الإيقاليبيويمي كما
+
+449
+00:41:02,410 --> 00:41:05,130
+تعلمين Y يقوم بالتخطيط لجهة الـ Aggregate
+
+450
+00:41:05,130 --> 00:41:09,750
+Expenditure لذلك Y يقوم بالتخطيط لـ C Plus I Plus
+
+451
+00:41:09,750 --> 00:41:19,370
+G لذلك Y يقوم بالتخطيط لـ C 300 Plus 0.8 Y D Plus
+
+452
+00:41:19,370 --> 00:41:33,040
+I200 plus g 400 right so y equals 300 plus 0.8
+
+453
+00:41:33,040 --> 00:41:41,300
+times yd is y minus t صح so y minus t is given the
+
+454
+00:41:41,300 --> 00:41:47,180
+tax the net tax is given so equals 200 plus 200
+
+455
+00:41:47,180 --> 00:41:57,490
+plus 400 صحSo Y equals 300 plus 200 plus 400
+
+456
+00:41:57,490 --> 00:42:09,930
+equals 900 plus 0.8Y minus 0.8 times 200 equals
+
+457
+00:42:09,930 --> 00:42:10,630
+160
+
+458
+00:42:13,290 --> 00:42:20,730
+مصبوح؟ So اعمل shifting هيك Y minus 0.8Y equals
+
+459
+00:42:20,730 --> 00:42:30,690
+900 minus 160 equals how much? 740 So this is one
+
+460
+00:42:30,690 --> 00:42:41,470
+0.2Y equals 740 So how much is Y? So Y equals
+
+461
+00:42:46,570 --> 00:42:56,350
+740 over 0.2 صح؟ So Y equals how much؟ That's it
+
+462
+00:42:56,350 --> 00:43:01,950
+B, the answer is B Right؟ How much is the
+
+463
+00:43:01,950 --> 00:43:05,230
+consumption in this case؟ Because that's a direct
+
+464
+00:43:05,230 --> 00:43:14,760
+substitution So C Yes أمسح هذا؟Okay, so calculate
+
+465
+00:43:14,760 --> 00:43:17,320
+the consumption, the aggregate consumption in this
+
+466
+00:43:17,320 --> 00:43:25,960
+case C equals 300 plus 0.8 times YD So, C equals
+
+467
+00:43:25,960 --> 00:43:31,660
+300 plus 0.8 times Y at equilibrium equals how
+
+468
+00:43:31,660 --> 00:43:44,270
+much? 3700 minus T, T equals how much?200 so C
+
+469
+00:43:44,270 --> 00:43:56,150
+equals 300 plus 0.8 times 3000 700 minus 200 3500
+
+470
+00:43:56,150 --> 00:44:04,530
+so C equals 300 plus how much the 0.8 times اعمله
+
+471
+00:44:04,530 --> 00:44:09,890
+مع الاهلة شوفوا how much
+
+472
+00:44:11,690 --> 00:44:18,970
+Okay two thousand eight hundred so c equals three
+
+473
+00:44:18,970 --> 00:44:23,010
+hundred three thousand one hundred billion dollars
+
+474
+00:44:23,010 --> 00:44:28,790
+so So as you see here the consumption equals how
+
+475
+00:44:28,790 --> 00:44:32,670
+much three thousand one hundred so the answer is a
+
+476
+00:44:32,670 --> 00:44:35,210
+right يعطيكم العشري
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/B1sxcr4enWA_raw.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/B1sxcr4enWA_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..303ff355e303f4b26bd239192a6673b4338495be
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/B1sxcr4enWA_raw.srt
@@ -0,0 +1,2020 @@
+1
+00:00:20,650 --> 00:00:23,990
+بسم الله الرحمن الرحيم اليوم ان شاء الله سنقوم
+
+2
+00:00:23,990 --> 00:00:27,310
+باختيار بعض التدريبات و بعض التدريبات الواقعية
+
+3
+00:00:27,310 --> 00:00:35,870
+مرتبطة بالقصة 4 و 5 قبل ان نكمل القصة 5 بشكل صحيح؟
+
+4
+00:00:35,870 --> 00:00:39,810
+لذلك لكي نتأكد أن كل شيء ماضي بشكل صحيح كل شيء
+
+5
+00:00:39,810 --> 00:00:43,190
+ماضي بشكل صحيح لذا دعونا ناخد التدريبات التالية
+
+6
+00:00:44,070 --> 00:00:49,690
+تجعلها أسهل تفهيم الدراسة كما تشاهد في هذا المثال
+
+7
+00:00:49,690 --> 00:00:55,230
+أو في هذا التعليق إذا كانت عملية استخدام C 100
+
+8
+00:00:55,230 --> 00:01:08,410
+plus 0.8Y و I 50 المسألة هي مستوى الميزاني هو كم؟
+
+9
+00:01:08,410 --> 00:01:14,740
+كما تعلمينإذا لم يكن هناك حكومة، فإن الانتجار يحدث
+
+10
+00:01:14,740 --> 00:01:20,260
+عندما Y يكوين أسعار الانتجار، فإن الانتجار يكوين
+
+11
+00:01:20,260 --> 00:01:24,460
+أسعار الانتجار وإذا لم يكن هناك حكومة، فإن أسعار
+
+12
+00:01:24,460 --> 00:01:30,000
+الانتجار يكوين كم؟ C بلس I، ففي الانتجار Y
+
+13
+00:01:37,140 --> 00:01:38,540
+YYYYYYYYYYYYYYYYYYY
+
+14
+00:01:49,250 --> 00:01:56,230
+-0.8y-0
+
+15
+00:01:56,230 --> 00:02:01,690
+.8y
+
+16
+00:02:01,690 --> 00:02:10,130
+-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y
+
+17
+00:02:10,130 --> 00:02:10,130
+-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y
+
+18
+00:02:10,130 --> 00:02:10,470
+-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y
+
+19
+00:02:10,470 --> 00:02:10,470
+-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y-0.8y
+
+20
+00:02:10,470 --> 00:02:12,630
+-0.8y-0.8y-0.8
+
+21
+00:02:23,110 --> 00:02:28,550
+ماذا عن المستخدم في هذه الحالة؟ كم هو المستخدم؟
+
+22
+00:02:31,450 --> 00:02:36,850
+exactly yes yes yes aggregate expenditure equals c
+
+23
+00:02:36,850 --> 00:02:41,610
+plus i the aggregate income equals c plus s right
+
+24
+00:02:41,610 --> 00:02:46,430
+so as we mentioned that at equilibrium the
+
+25
+00:02:46,430 --> 00:02:49,390
+aggregate income equals aggregate expenditure
+
+26
+00:02:49,390 --> 00:02:52,550
+right or the aggregate output equals the aggregate
+
+27
+00:02:52,550 --> 00:02:58,470
+expenditureتخيل قيمة الانتجار أو الانتجار المجموعة
+
+28
+00:02:58,470 --> 00:03:05,070
+في الانتجار الانتجار الانتجار الانتجار الانتجار
+
+29
+00:03:05,070 --> 00:03:09,230
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+30
+00:03:09,230 --> 00:03:12,150
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+31
+00:03:12,150 --> 00:03:13,090
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+32
+00:03:13,090 --> 00:03:13,090
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+33
+00:03:13,090 --> 00:03:13,090
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+34
+00:03:13,090 --> 00:03:13,090
+الانتجار الانتجار الانتجار الانتجار الانتجار
+
+35
+00:03:13,090 --> 00:03:21,710
+الانتجار الانتجار الانتجار الانتجار الانتجار ال
+
+36
+00:03:25,220 --> 00:03:28,340
+هذا هو ايقاليبريم التخزين أو قيمة التخزين في
+
+37
+00:03:28,340 --> 00:03:36,580
+ايقاليبريم اذا C ايقال 100 plus 0.8 times 750 كم
+
+38
+00:03:36,580 --> 00:03:45,320
+كده كده كده كده كده كده كده كده كده كده كده كده
+
+39
+00:03:45,320 --> 00:03:45,320
+كده كده كده كده كده كده كده كده كده كده كده كده
+
+40
+00:03:45,320 --> 00:03:45,380
+كده كده كده كده كده كده كده كده كده كده كده كده
+
+41
+00:03:45,380 --> 00:03:46,380
+كده كده كده كده كده كده كده كده كده كده كده كده
+
+42
+00:03:46,380 --> 00:03:50,780
+كده كده
+
+43
+00:03:50,780 --> 00:03:57,130
+كده كده كده كده كده كده كده كده كدSaving equals Y
+
+44
+00:03:57,130 --> 00:04:07,510
+minus C So it should be 700 What about the
+
+45
+00:04:07,510 --> 00:04:12,550
+aggregate saving? Saving equals Y minus C when
+
+46
+00:04:12,550 --> 00:04:17,270
+there is no government So S saving equals Y minus
+
+47
+00:04:17,270 --> 00:04:23,700
+Cالسعر يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+48
+00:04:23,700 --> 00:04:24,540
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+49
+00:04:24,540 --> 00:04:25,380
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+50
+00:04:25,380 --> 00:04:25,580
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+51
+00:04:25,580 --> 00:04:25,700
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+52
+00:04:25,700 --> 00:04:25,700
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+53
+00:04:25,700 --> 00:04:26,700
+باستخدام Y يقوم باستخدام Y يقوم باستخدام Y يقوم
+
+54
+00:04:26,700 --> 00:04:46,540
+باستخدام Y يقوم باستخدام Y
+
+55
+00:04:51,290 --> 00:05:01,230
+كما تشاهد، فإن عملي التخزين يقل 1500 plus 0.75Y I
+
+56
+00:05:01,230 --> 00:05:07,470
+يقل 500 مليون دولار فالسؤال هو إذا كان عملي
+
+57
+00:05:07,470 --> 00:05:11,190
+التخزين يقل عملي التخزين في مستوى نسخة نسخة نسخة
+
+58
+00:05:11,190 --> 00:05:15,750
+نسخة نسخة
+
+59
+00:05:17,420 --> 00:05:22,700
+السؤال هو إذا
+
+60
+00:05:22,700 --> 00:05:28,120
+S
+
+61
+00:05:28,120 --> 00:05:34,600
+إقل I، إذا S إقل I، إذا S إقل I، إذا S إقل I، إذا
+
+62
+00:05:34,600 --> 00:05:35,520
+S إقل I، إذا S إقل I، إذا S إقل I، إذا S إقل I،
+
+63
+00:05:35,520 --> 00:05:35,940
+إذا S إقل I، إذا S إقل I، إذا S إقل I، إذا S إقل
+
+64
+00:05:35,940 --> 00:05:35,940
+I، إذا S إقل I، إذا S إقل I، إذا S إقل I، إذا S
+
+65
+00:05:35,940 --> 00:05:35,940
+إقل I، إذا S إقل I، إذا S إقل I، إذا S إقل I، إذا
+
+66
+00:05:35,940 --> 00:05:35,940
+S إقل I، إذا S إقل I، إذا S إقل I، إذا S إقل I،
+
+67
+00:05:35,940 --> 00:05:36,880
+إذا S إقل I، إذا S إقل I، إذا S إقل I، إذا S إقل
+
+68
+00:05:36,880 --> 00:05:42,510
+I، إذا Swhen y equals aggregate expenditure C plus
+
+69
+00:05:42,510 --> 00:05:47,170
+S equals C plus I so deduction of C so S equals I
+
+70
+00:05:47,170 --> 00:05:51,270
+at equilibrium so the same we have to do the same
+
+71
+00:05:51,270 --> 00:05:54,790
+to derive the equilibrium aggregate output the
+
+72
+00:05:54,790 --> 00:05:57,950
+equilibrium aggregate output in this case equals C
+
+73
+00:05:57,950 --> 00:06:04,470
+plus I the same so in this case أمسح هذا
+
+74
+00:06:20,450 --> 00:06:25,710
+السؤال هو تخطيط الميزة التجاربية أو الميزة
+
+75
+00:06:25,710 --> 00:06:29,670
+التجاربية الاجتماعية عندما تخطيط الميزة التجاربية
+
+76
+00:06:29,670 --> 00:06:30,310
+أو الميزة التجاربية
+
+77
+00:06:34,070 --> 00:06:42,270
+يكون y يكون c plus i في الانتجار يكون y يكون 1500
+
+78
+00:06:42,270 --> 00:06:48,950
+plus 0.75 y plus 500 مليون دولار في الانتجار يكون
+
+79
+00:06:48,950 --> 00:06:58,670
+y يكون 2000 plus 0.75 y يكون y يكون 2000 plus 0.75
+
+80
+00:06:58,670 --> 00:07:08,100
+y يكونEquals 2000 So Zero Point Yes 25Y Equals
+
+81
+00:07:08,100 --> 00:07:15,660
+2000 So Y Equals 8000 Million Dollars That's It So
+
+82
+00:07:15,660 --> 00:07:21,720
+At Equilibrium The Aggregate Output Equals 8000
+
+83
+00:07:21,720 --> 00:07:24,380
+Million Dollars How Much Is The Consumption In
+
+84
+00:07:24,380 --> 00:07:27,200
+This Case Dark Substitution Of The Consumption
+
+85
+00:07:27,200 --> 00:07:34,550
+Function صحلتخطيط أو تخطيط استخدام المجموعة C يقل
+
+86
+00:07:34,550 --> 00:07:45,050
+كم؟ C يقل 1500 plus 0.75 times Y يقل 8000 مليون
+
+87
+00:07:45,050 --> 00:07:59,310
+دولار C يقل 1500 plus كم؟ هل أنت متأكد؟6000 مليون
+
+88
+00:07:59,310 --> 00:08:10,590
+دولار او 7500 مليون دولار او
+
+89
+00:08:10,590 --> 00:08:14,710
+7500 مليون دولار
+
+90
+00:08:17,160 --> 00:08:24,500
+-7500-500 يعني أن هذا هو المساعدة الأساسية أو
+
+91
+00:08:24,500 --> 00:08:25,800
+المساعدة الأساسية
+
+92
+00:08:30,970 --> 00:08:36,210
+نعم، نفس الفكرة، نفس البرنامج. لذلك، دعنا نذهب إلى
+
+93
+00:08:36,210 --> 00:08:40,510
+هذه الفيجورة أو هذا البرنامج. كما ترى، هذا هو
+
+94
+00:08:40,510 --> 00:08:44,570
+عملية المساعدة العضلية. A عملية المساعدة العضلية
+
+95
+00:08:44,570 --> 00:08:52,350
+يعني C plus I وهذا Y. يحدث الانعكاس عندما Y يعني
+
+96
+00:08:52,350 --> 00:08:55,370
+عملية المساعدة العضلية. هذا عملية المساعدة العضلية
+
+97
+00:08:55,370 --> 00:08:56,310
+Y.
+
+98
+00:08:58,410 --> 00:08:59,910
+وهذا Y.
+
+99
+00:09:03,470 --> 00:09:07,550
+الإيقاليبريام كما ترى يحدث عند Y إيقاليبريام
+
+100
+00:09:07,550 --> 00:09:13,790
+اتساقط افعالية اجرية ايه؟ اذا كم هو ال .. او كم هو
+
+101
+00:09:13,790 --> 00:09:15,910
+ال .. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه
+
+102
+00:09:15,910 --> 00:09:16,730
+.. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه ..
+
+103
+00:09:16,730 --> 00:09:17,050
+اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه
+
+104
+00:09:17,050 --> 00:09:18,570
+.. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه ..
+
+105
+00:09:18,570 --> 00:09:18,570
+اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه
+
+106
+00:09:18,570 --> 00:09:20,010
+.. اه .. اه .. اه .. اه .. اه .. اه .. اه .. اه ..
+
+107
+00:09:20,010 --> 00:09:23,690
+اه .. اه .. اه .. اه .. اه ..
+
+108
+00:09:28,380 --> 00:09:34,820
+derive the aggregate expenditure function
+
+109
+00:09:34,820 --> 00:09:39,700
+as you know that the aggregate expenditure
+
+110
+00:09:39,700 --> 00:09:43,020
+function includes the autonomous aggregate
+
+111
+00:09:43,020 --> 00:09:47,540
+expenditure plus the slope of the function times y
+
+112
+00:09:50,000 --> 00:09:54,140
+او او او او او او او او او او او او او او او او او
+
+113
+00:09:54,140 --> 00:09:55,340
+او او او او او او او او او او او او او او او او او
+
+114
+00:09:55,340 --> 00:10:01,440
+او او او او او او او او او او او او او او او او او
+
+115
+00:10:01,440 --> 00:10:03,480
+او او او او او او او او او او او او او او او او او
+
+116
+00:10:03,480 --> 00:10:08,300
+او او او او او
+
+117
+00:10:11,510 --> 00:10:16,770
+هذه المقارنة على هذه المقارنة لكتابة مقارنة
+
+118
+00:10:16,770 --> 00:10:18,290
+الهزيمة التي تستخدمها
+
+119
+00:10:22,790 --> 00:10:28,070
+-150 over 200 This is the marginal propensity to
+
+120
+00:10:28,070 --> 00:10:32,990
+consume, صح؟ So aggregate expenditure function in
+
+121
+00:10:32,990 --> 00:10:36,430
+this case equals the autonomous aggregate
+
+122
+00:10:36,430 --> 00:10:42,870
+expenditure which equals 150 plus the MBC times Y,
+
+123
+00:10:43,010 --> 00:10:48,090
+صح؟ MBC equals how much? MBC in this case equals
+
+124
+00:10:49,470 --> 00:10:51,670
+السلوب بالضبط سلوب عملية عملية عملية عملية عملية
+
+125
+00:10:51,670 --> 00:10:54,030
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+126
+00:10:54,030 --> 00:10:55,690
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+127
+00:10:55,690 --> 00:10:55,990
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+128
+00:10:55,990 --> 00:10:56,930
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+129
+00:10:56,930 --> 00:10:57,570
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+130
+00:10:57,570 --> 00:10:57,590
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+131
+00:10:57,590 --> 00:10:58,190
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+132
+00:10:58,190 --> 00:10:58,190
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+133
+00:10:58,190 --> 00:11:18,650
+عملية عمل
+
+134
+00:11:19,860 --> 00:11:25,360
+At equilibrium mathematically حسبولنا ال Y و ال
+
+135
+00:11:25,360 --> 00:11:25,960
+consumption
+
+136
+00:11:46,720 --> 00:12:00,760
+Y-0.25Y-0.25Yزي 0.75 Y يقل 150، فY يقل كم؟ 200،
+
+137
+00:12:00,760 --> 00:12:06,100
+بالضبط، يجب أن يكون 200، لأن الاتصال هو 200، كما
+
+138
+00:12:06,100 --> 00:12:11,580
+ترى، صحيح؟ ماذا
+
+139
+00:12:11,580 --> 00:12:16,970
+أخر؟calculate the investment multiplier or the
+
+140
+00:12:16,970 --> 00:12:19,950
+value of investment multiplier the question is
+
+141
+00:12:19,950 --> 00:12:25,390
+calculate the investment multiplier the investment
+
+142
+00:12:25,390 --> 00:12:29,130
+multiplier equals how much or what's what's the
+
+143
+00:12:29,130 --> 00:12:32,950
+formula of the investment multiplier one over
+
+144
+00:12:37,520 --> 00:12:42,320
+السؤال هو تخطيط المزيد من المستخدمين المستخدمين
+
+145
+00:12:42,320 --> 00:12:44,780
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+146
+00:12:44,780 --> 00:12:45,020
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+147
+00:12:45,020 --> 00:12:45,540
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+148
+00:12:45,540 --> 00:12:46,020
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+149
+00:12:46,020 --> 00:12:48,100
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+150
+00:12:48,100 --> 00:12:48,500
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+151
+00:12:48,500 --> 00:12:48,500
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+152
+00:12:48,500 --> 00:12:49,320
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+153
+00:12:49,320 --> 00:12:50,200
+المستخدمين المستخدمين المستخدمين المستخدمين
+
+154
+00:12:50,200 --> 00:12:55,460
+المستخدمين المستخدمين المستخدمين
+
+155
+00:12:55,460 --> 00:13:00,330
+المستخدمينمع ذلك، الـ Investment Multiplier يقوم
+
+156
+00:13:00,330 --> 00:13:03,250
+بالتخلص من 1 على 1 مقارنة 1 مقارنة 1 مقارنة 1
+
+157
+00:13:03,250 --> 00:13:06,290
+مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1
+
+158
+00:13:06,290 --> 00:13:09,350
+مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1 مقارنة 1
+
+159
+00:13:09,350 --> 00:13:15,370
+مقارنة 1 مقارنة 1 مقارنة 1 مقارنة
+
+160
+00:13:20,410 --> 00:13:25,150
+1.33 مليون دولار، هذا يعني أنه إذا ارتكاب
+
+161
+00:13:25,150 --> 00:13:28,910
+الاستثمار او الاستثمار المخطط ارتكب 1 مليون دولار،
+
+162
+00:13:28,910 --> 00:13:30,550
+فإن نسبة الاستثمار المخطط أو الاستثمار المخطط
+
+163
+00:13:30,550 --> 00:13:39,710
+سترتكب 1.33 مليون دولار، صح؟ حسنا؟ طيب، اعتقد ان
+
+164
+00:13:39,710 --> 00:13:42,090
+الاستثمار المخطط ارتكب
+
+165
+00:13:46,320 --> 00:13:51,780
+50 مليون دولار المسألة هي .. اعتبار ان الاستثمار
+
+166
+00:13:51,780 --> 00:13:58,480
+المخطط يزيد من 50 مليون دولار كم هو قيمة التغيير
+
+167
+00:13:58,480 --> 00:14:01,740
+في الاختصار التجاربية او الاستثمار التجاربي يعني
+
+168
+00:14:01,740 --> 00:14:07,860
+اعتبار ان الاستثمار التجاربي يزيد من 50 مليون
+
+169
+00:14:07,860 --> 00:14:16,930
+دولار هذا دلتا I دلتا I يقل50 مليون دولار صح؟
+
+170
+00:14:16,930 --> 00:14:22,310
+السؤال هو تخطيط او نعم تخطيط التغيير في الانتجار
+
+171
+00:14:22,310 --> 00:14:27,910
+التجاري والتحكم في الانتجار التجاري الجديد على
+
+172
+00:14:27,910 --> 00:14:33,770
+الفيرمين أو على الفجر نفس الشيء نعم، لذلك كما
+
+173
+00:14:33,770 --> 00:14:40,730
+تعلمين أن دلتا Y عبر دلتا I اكتر واحد عبر MBS او
+
+174
+00:14:40,730 --> 00:14:47,390
+واحد مانوس MBC، لذلك دلتا Yمفروض ان دلتا اي مفروض
+
+175
+00:14:47,390 --> 00:15:03,970
+ان دلتا
+
+176
+00:15:03,970 --> 00:15:17,820
+اي مفروض ان دلتا ايمع 0.75 مرة مرة مرة مرة مرة مرة
+
+177
+00:15:17,820 --> 00:15:18,040
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+178
+00:15:18,040 --> 00:15:18,240
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+179
+00:15:18,240 --> 00:15:18,560
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+180
+00:15:18,560 --> 00:15:18,560
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+181
+00:15:18,560 --> 00:15:18,880
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+182
+00:15:18,880 --> 00:15:19,600
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+183
+00:15:19,600 --> 00:15:20,480
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+184
+00:15:20,480 --> 00:15:24,380
+مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة مرة
+
+185
+00:15:24,380 --> 00:15:31,870
+مرة مرة مرة مرة مرة مرة مرة م66.6% هذا ما هو
+
+186
+00:15:31,870 --> 00:15:34,830
+التغيير في الميزة التجارية أو الميزة التجارية
+
+187
+00:15:34,830 --> 00:15:40,310
+الخاصة بكفة ميزة التجارة الخاصة بكفة ميزة التجارة
+
+188
+00:15:40,310 --> 00:15:41,570
+الخاصة بكفة ميزة التجارة الخاصة بكفة ميزة التجارة
+
+189
+00:15:41,570 --> 00:15:47,110
+الخاصة بكفة ميزة التجارة الخاصة بكفة ميزة التجارة
+
+190
+00:15:47,110 --> 00:15:47,190
+الخاصة بكفة M
+
+191
+00:15:58,320 --> 00:16:01,980
+266.6 مليار دولار ، وهذا هو الانقلاب الجديد ، لذلك
+
+192
+00:16:01,980 --> 00:16:07,180
+نتوقع أن يكون هناك انقلاب جديد في هذا النقطة ،
+
+193
+00:16:07,180 --> 00:16:13,960
+لذلك لدينا تغيير كامل أو تغيير أعلى من عملية
+
+194
+00:16:13,960 --> 00:16:18,520
+التجارب التجاربية ، لذلك هذا هو تجارب التجارب
+
+195
+00:16:18,520 --> 00:16:21,760
+التجاربية 2 C plus I plus Delta I
+
+196
+00:16:25,870 --> 00:16:31,170
+and this is the new equilibrium output or income
+
+197
+00:16:31,170 --> 00:16:39,310
+yes exactly 66.6 is the increasing of aggregate
+
+198
+00:16:39,310 --> 00:16:41,890
+income or the increasing of aggregate output
+
+199
+00:17:02,420 --> 00:17:12,540
+القيمة المرتبطة تغيير
+
+200
+00:17:12,540 --> 00:17:23,440
+ايقاليبرام اكسبورت حسنا
+
+201
+00:17:23,440 --> 00:17:26,800
+دعونا
+
+202
+00:17:26,800 --> 00:17:28,420
+نأخذ التالي
+
+203
+00:17:36,040 --> 00:17:38,960
+كما ترى لدينا المعلومات التالتة مباشرة مباشرة
+
+204
+00:17:38,960 --> 00:17:44,280
+مباشرة مباشرة مباشرة
+
+205
+00:17:44,280 --> 00:17:47,060
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+206
+00:17:47,060 --> 00:17:48,340
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+207
+00:17:48,340 --> 00:17:48,620
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+208
+00:17:48,620 --> 00:17:48,840
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+209
+00:17:48,840 --> 00:17:48,840
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+210
+00:17:48,840 --> 00:17:50,320
+مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة مباشرة
+
+211
+00:17:50,320 --> 00:18:00,540
+مباشرة مباشرة مباشرة مباشرة مباشرة
+
+212
+00:18:01,940 --> 00:18:10,300
+مبسفة مبسفة مبسفة مبسفة مبسفة مبسفة
+
+213
+00:18:10,300 --> 00:18:16,300
+مبسفة مبسفة مبسفة مبسفة
+
+214
+00:18:16,300 --> 00:18:23,220
+مبسفة مبسفة مبسفة مبسفة
+
+215
+00:18:23,220 --> 00:18:30,300
+مبسفة مبسفة مبسفة مبسفة مبسفة مبسفة مبسفة مبسفة
+
+216
+00:18:33,100 --> 00:18:36,020
+الانبعاد الوضعي يزيد من نفس المقاومة 50 مليون
+
+217
+00:18:36,020 --> 00:18:40,760
+دولار اتخاذ التغيير في الميزة التجاربية نفس الفكرة
+
+218
+00:18:40,760 --> 00:18:47,660
+لذا دلتا Y على دلتا I اكتر من 1 على MPS لذلك دلتا
+
+219
+00:18:47,660 --> 00:18:53,560
+Y على دلتا I 50 اكتر من 1 على 0.70
+
+220
+00:18:55,920 --> 00:19:05,020
+دلتا Y اكتر من 50 اكتر من 0.70 اكتر من 71
+
+221
+00:19:05,020 --> 00:19:09,820
+.4
+
+222
+00:19:15,040 --> 00:19:18,840
+بالتالي، الانقراز كما ترى، الانقراز من قيمة الـ
+
+223
+00:19:18,840 --> 00:19:23,240
+MBC الـ Margin Propensity Consumed يتسبب في انقراز
+
+224
+00:19:23,240 --> 00:19:27,020
+القيمة أو التغيير في الميزة التجارية أو الميزة
+
+225
+00:19:27,020 --> 00:19:30,940
+التجارية الصح؟ في المرة الأولى، الـ MBC في الحالة
+
+226
+00:19:30,940 --> 00:19:35,700
+السابقة، عندما ميزة الـ MBC كانت 0.25 ميزة كم هي
+
+227
+00:19:35,700 --> 00:19:39,540
+انقراز الميزة التجارية؟ 66.6 ميزة تجارية، صح؟ لكن
+
+228
+00:19:39,540 --> 00:19:44,080
+الآن، انقراز MBC يتسبب في انقراز الميزة التجارية
+
+229
+00:19:49,000 --> 00:19:55,980
+الشيء نفسه ..الشيء نفسه ..الشيء نفسه
+
+230
+00:19:55,980 --> 00:19:59,620
+..الشيء نفسه
+
+231
+00:19:59,620 --> 00:20:01,840
+..الشيء نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء
+
+232
+00:20:01,840 --> 00:20:03,560
+نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء نفسه
+
+233
+00:20:03,560 --> 00:20:03,900
+..الشيء نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء
+
+234
+00:20:03,900 --> 00:20:03,900
+نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء نفسه
+
+235
+00:20:03,900 --> 00:20:03,900
+..الشيء نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء
+
+236
+00:20:03,900 --> 00:20:03,900
+نفسه ..الشيء نفسه ..الشيء نفسه ..الشيء نفسه
+
+237
+00:20:03,900 --> 00:20:04,080
+..الشيء نفسه ..الشيء نفسه ..الشيء نفسه ..
+
+238
+00:20:12,870 --> 00:20:15,990
+في السابق .. نعم .. نعم .. نعم .. نعم .. في السابق
+
+239
+00:20:15,990 --> 00:20:26,230
+عندما MBC كانت 0.25 MBS 0.75 .. الأن عندما MBC أقل
+
+240
+00:20:26,230 --> 00:20:37,950
+0.30 MBS أقل 0.70 .. هذا هو .. حسنا؟ لا .. حسنا ..
+
+241
+00:20:37,950 --> 00:20:41,630
+MBC aggregate equilibrium
+
+242
+00:20:43,690 --> 00:20:49,470
+حسنًا دعونا نذهب إلى هذا المثال السؤال
+
+243
+00:20:49,470 --> 00:20:57,110
+هو اعتمد أنه لا يوجد حكومة أو مجتمع غير مجتمع لذلك
+
+244
+00:20:57,110 --> 00:21:03,530
+لا يوجد حكومة ونعمل تحت اقتصاد قريب إذا
+
+245
+00:21:03,530 --> 00:21:07,870
+كتابة الـ Multiplier هو او يقل 10 كتابة ال
+
+246
+00:21:07,870 --> 00:21:09,610
+Multiplier
+
+247
+00:21:13,220 --> 00:21:18,180
+10 مليون دولار تقريبًا 10 مليون دولار تقريبًا
+
+248
+00:21:18,180 --> 00:21:18,960
+تقريبًا 10 مليون دولار تقريبًا 10 مليون دولار
+
+249
+00:21:18,960 --> 00:21:18,960
+تقريبًا 10 مليون دولار تقريبًا 10 مليون دولار
+
+250
+00:21:18,960 --> 00:21:22,120
+تقريبًا 10 مليون دولار تقريبًا 10 مليون دولار
+
+251
+00:21:22,120 --> 00:21:24,920
+تقريبًا 10 مليون دولار تقريبًا 10 مليون دولار
+
+252
+00:21:24,920 --> 00:21:28,660
+تقريبًا 10 مليون دولار تقريبًا 10 مليون دولار
+
+253
+00:21:28,660 --> 00:21:35,440
+تقريبًا 10 مليون دولار تقريبًا 10
+
+254
+00:21:35,440 --> 00:21:42,020
+مليون دولار تقريبًاالسؤال هو تخطيط التغيير في الـ
+
+255
+00:21:42,020 --> 00:21:44,060
+aggregate output أو الاتجار التجاري أو الاتجار
+
+256
+00:21:44,060 --> 00:21:45,520
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+257
+00:21:45,520 --> 00:21:48,720
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+258
+00:21:48,720 --> 00:21:50,440
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+259
+00:21:50,440 --> 00:21:53,000
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+260
+00:21:53,000 --> 00:21:54,400
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+261
+00:21:54,400 --> 00:21:55,180
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+262
+00:21:55,180 --> 00:21:55,580
+التجاري أو الاتجار التجاري أو الاتجار التجاري أو
+
+263
+00:21:55,580 --> 00:21:58,160
+الاتجار التجاري أو الاتجار التجاري أو الاتجار
+
+264
+00:21:58,160 --> 00:22:04,640
+التجاري أو
+
+265
+00:22:04,640 --> 00:22:11,570
+الاتجار التجصح or to ignore this part so
+
+266
+00:22:11,570 --> 00:22:16,710
+multiplier 10 equals delta y over 10 so delta y
+
+267
+00:22:16,710 --> 00:22:20,530
+equals positive this is positive positive one
+
+268
+00:22:20,530 --> 00:22:23,650
+hundred so we expect that the aggregate output
+
+269
+00:22:23,650 --> 00:22:27,610
+would increase by one hundred billion dollars
+
+270
+00:22:27,610 --> 00:22:34,750
+right yes ربيعبس الواحد على واحد مانس MBC والله
+
+271
+00:22:34,750 --> 00:22:38,710
+عندي .. ال one .. the multiplier equals one over
+
+272
+00:22:38,710 --> 00:22:43,330
+.. one minus MBC, so one minus MBC is MPS حسب
+
+273
+00:22:43,330 --> 00:22:45,470
+الموضوع .. حسب الموضوع .. yes it depends .. yes
+
+274
+00:22:45,470 --> 00:22:53,110
+exactly طيب and this .. and this exercise what do
+
+275
+00:22:53,110 --> 00:22:59,380
+you seeلسنا لدينا حكومة وليس لدينا عالم خارق إذا
+
+276
+00:22:59,380 --> 00:23:05,740
+كان مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2 مبيعات
+
+277
+00:23:05,740 --> 00:23:08,240
+الـ MBS 0.2 مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2
+
+278
+00:23:08,240 --> 00:23:08,560
+مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2 مبيعات الـ
+
+279
+00:23:08,560 --> 00:23:10,320
+MBS 0.2 مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2
+
+280
+00:23:10,320 --> 00:23:10,320
+مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2 مبيعات الـ
+
+281
+00:23:10,320 --> 00:23:10,320
+MBS 0.2 مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2
+
+282
+00:23:10,320 --> 00:23:12,440
+مبيعات الـ MBS 0.2 مبيعات الـ MBS 0.2 مبيعات الـ
+
+283
+00:23:12,440 --> 00:23:17,550
+MBS 0.2 مبيلذلك في هذه الحالة بيكسل بيكسل بيكسل
+
+284
+00:23:17,550 --> 00:23:18,150
+بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل
+
+285
+00:23:18,150 --> 00:23:21,670
+بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل بيكسل
+
+286
+00:23:21,670 --> 00:23:30,750
+بيكسل بيكسل
+
+287
+00:23:31,340 --> 00:23:36,840
+عشان تعرف ان دلتا Y عشان دلتا I اكوال 1 عشان MBS
+
+288
+00:23:36,840 --> 00:23:43,320
+او 1 مانوس MBC دلتا Y عشان مانوس مانوس مانوس مانوس
+
+289
+00:23:43,320 --> 00:23:45,680
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+290
+00:23:45,680 --> 00:23:45,680
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+291
+00:23:45,680 --> 00:23:47,100
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+292
+00:23:47,100 --> 00:23:48,820
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+293
+00:23:48,820 --> 00:23:48,820
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+294
+00:23:48,820 --> 00:23:48,860
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مانوس
+
+295
+00:23:48,860 --> 00:24:00,300
+مانوس مانوس مانوس مانوس مانوس مانوس مانوس مان
+
+296
+00:24:02,340 --> 00:24:10,340
+so sorry no to decrease pie yes yes so we expect
+
+297
+00:24:10,340 --> 00:24:14,080
+that we have a decrease in aggregate output by 200
+
+298
+00:24:14,080 --> 00:24:20,400
+million درهز sorry جايين لل governmentلا لسنا
+
+299
+00:24:20,400 --> 00:24:25,120
+نتكلم عن الحكومة، لسنا لدينا حكومة هنا، حسنا؟
+
+300
+00:24:25,120 --> 00:24:31,500
+حسنا، دعنا نذهب و نأخذ أو نأخذ بعض التعليمات لقصة
+
+301
+00:24:31,500 --> 00:24:37,060
+5 عندما نضيف الحكومة و مستخدم الـ aggregate، حسنا؟
+
+302
+00:24:43,280 --> 00:24:47,700
+كما تشاهد في هذا المثال، عملي الـ Pell هو 1000$
+
+303
+00:24:47,700 --> 00:24:54,080
+وعقله الـ net taxes هي 35350$ وعقله الـ disposable
+
+304
+00:24:54,080 --> 00:24:59,740
+income هو كم؟ عملي الـ disposable income هو YD يقل
+
+305
+00:24:59,740 --> 00:25:10,440
+Y-T لذلك YD يقل Y1000-350 يقل 650
+
+306
+00:25:13,150 --> 00:25:19,170
+right this is the first بلاش ييجي زيي و دي يجي
+
+307
+00:25:19,170 --> 00:25:29,410
+أصعب علمك الأصعب هنا عشان ما yes exactly طيب
+
+308
+00:25:29,410 --> 00:25:37,040
+in this example in 2007المدينة كامفيل قمت بتجميع
+
+309
+00:25:37,040 --> 00:25:45,600
+500 ألف دولار من التجارب التجارب تي اكواس 500 ألف
+
+310
+00:25:45,600 --> 00:25:47,320
+مليون دولار او دولار
+
+311
+00:26:03,700 --> 00:26:10,000
+We have a deficit because the taxes gained
+
+312
+00:26:10,000 --> 00:26:13,660
+or received is larger than the government spending
+
+313
+00:26:13,660 --> 00:26:17,880
+So we have a surplus by how much the difference
+
+314
+00:26:17,880 --> 00:26:22,440
+between G and T صح؟ مين أكبر؟ الإنفاق ولا الضريب
+
+315
+00:26:22,440 --> 00:26:25,800
+اللي جمعناها؟ مجمعين ضريب، لذا we have a surplus
+
+316
+00:26:25,800 --> 00:26:28,820
+by fifty thousand dollars
+
+317
+00:26:34,100 --> 00:26:43,000
+حسنًا دعونا نذهب إلى هذا المثال أو التعليم كما
+
+318
+00:26:43,000 --> 00:26:51,380
+ترى عملية استخدام المجموعة هي C يكوين 100 plus 0
+
+319
+00:26:51,380 --> 00:27:01,320
+.6YD ماذا أخر؟ المال Y يكوين 1000 وY يكوين 1000
+
+320
+00:27:01,320 --> 00:27:13,250
+دولاروالدفع الوضعي هو T يقل 300$ تقل كم؟ YD او
+
+321
+00:27:13,250 --> 00:27:21,830
+يمكننا استخدام الفرمولة C يقل 100 plus 0.6 YD YD
+
+322
+00:27:21,830 --> 00:27:31,460
+يقل Y minus T تغيير YD يقل Y minus Tyes exactly so
+
+323
+00:27:31,460 --> 00:27:35,980
+c equals one hundred plus zero point six times y
+
+324
+00:27:35,980 --> 00:27:42,020
+minus the taxes three three hundred right so what
+
+325
+00:27:42,020 --> 00:27:46,400
+do you see so c equals one hundred so y is given
+
+326
+00:27:46,400 --> 00:27:52,240
+exactly sorry yes y is given one thousand dollars
+
+327
+00:27:53,050 --> 00:28:02,270
+So C equals 100 plus 0.6 times 700 So C equals 100
+
+328
+00:28:02,270 --> 00:28:06,310
+plus 420
+
+329
+00:28:06,310 --> 00:28:15,070
+So C equals 520 Right Is
+
+330
+00:28:15,070 --> 00:28:25,270
+it clear طيب How much is the savingبالضبط كما
+
+331
+00:28:25,270 --> 00:28:29,210
+تعلمين إذا كان لدينا حكومة إذا كان هناك حكومة
+
+332
+00:28:29,210 --> 00:28:38,130
+يكوين C بلس S بلس T لأن جزء من حصتك يذهب للعيارات
+
+333
+00:28:38,130 --> 00:28:44,570
+لذلك لكي تتخيل حفظ في هذه الحالة حفظ يكوين Y minus
+
+334
+00:28:44,570 --> 00:28:53,960
+T minus C أو YD minus CSo CS saving equals YD
+
+335
+00:28:53,960 --> 00:29:01,640
+minus T minus C Or Y minus T minus C That's it So
+
+336
+00:29:01,640 --> 00:29:13,040
+S equals Y equals 1000 minus T taxes 300 minus C
+
+337
+00:29:13,040 --> 00:29:15,920
+520 صح
+
+338
+00:29:19,100 --> 00:29:22,380
+520 مقارنة بمقارنة مقارنة مقارنة مقارنة مقارنة
+
+339
+00:29:22,380 --> 00:29:23,780
+مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة
+
+340
+00:29:23,780 --> 00:29:33,800
+مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة مقارنة
+
+341
+00:29:33,800 --> 00:29:45,160
+مقارنة
+
+342
+00:29:47,010 --> 00:29:51,550
+ولكن هنا يجب أن يكون مرتبط بـ yd بالضبط، لذلك
+
+343
+00:29:51,550 --> 00:29:57,150
+الاختيار في هذه الحالة يقل a plus b times yd وليس
+
+344
+00:29:57,150 --> 00:30:04,960
+yأو مانوس اي بلس اكي بلس وان مانوس بي مبس مبس مبس
+
+345
+00:30:04,960 --> 00:30:08,660
+مبس وي دي مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+346
+00:30:08,660 --> 00:30:08,660
+مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+347
+00:30:08,660 --> 00:30:08,680
+مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+348
+00:30:08,680 --> 00:30:09,860
+مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+349
+00:30:09,860 --> 00:30:13,360
+مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس مبس
+
+350
+00:30:13,360 --> 00:30:26,840
+مبس مبس مبس مب
+
+351
+00:30:27,070 --> 00:30:36,350
+-100 plus 40yd صح the same so let's go to another
+
+352
+00:30:36,350 --> 00:30:38,590
+exercise or example
+
+353
+00:30:45,650 --> 00:30:50,970
+هنا لدينا عملية استخدام المجتمع C يقل 100 اضافة 0
+
+354
+00:30:50,970 --> 00:30:57,310
+.8 YD وانتجة 600 ولا تكتفية يقل 0 لذا Y يقل نفس
+
+355
+00:30:57,310 --> 00:31:02,710
+المفهوم نفس البرنامج ولكن تكتفية يقل 0 في هذه
+
+356
+00:31:02,710 --> 00:31:07,530
+الحالة لذا يجب أن يكون Y يقل YD صح؟ لذلك دعونا
+
+357
+00:31:07,530 --> 00:31:10,430
+نذهب إلى هذا المثال
+
+358
+00:31:14,320 --> 00:31:17,440
+في هذا المثال، هذا هو السبب لإيقاف الميزة
+
+359
+00:31:17,440 --> 00:31:21,440
+التجارية، هذا هو C ، T تقاليد التجارة التجارية
+
+360
+00:31:21,440 --> 00:31:22,540
+التجارية التجارية التجارية التجارية التجارية
+
+361
+00:31:22,540 --> 00:31:23,580
+التجارية التجارية التجارية التجارية التجارية
+
+362
+00:31:23,580 --> 00:31:23,620
+التجارية التجارية التجارية التجارية التجارية
+
+363
+00:31:23,620 --> 00:31:24,060
+التجارية التجارية التجارية التجارية التجارية
+
+364
+00:31:24,060 --> 00:31:25,900
+التجارية التجارية التجارية التجارية التجارية
+
+365
+00:31:25,900 --> 00:31:25,900
+التجارية التجارية التجارية التجارية التجارية
+
+366
+00:31:25,900 --> 00:31:26,620
+التجارية التجارية التجارية التجارية التجارية
+
+367
+00:31:26,620 --> 00:31:26,620
+التجارية التجارية التجارية التجارية التجارية
+
+368
+00:31:26,620 --> 00:31:37,780
+التجارية التجارية التجارية التجارية التجارية
+
+369
+00:31:37,780 --> 00:31:47,260
+التجلذلك في الحالة الأولى C اضافة I اضافة G اضافة
+
+370
+00:31:47,260 --> 00:31:54,580
+اضافة اضافة اقوى C اضافة I اضافة G اضافة اقوى C
+
+371
+00:31:54,580 --> 00:31:57,800
+اضافة I اضافة G اضافة اقوى C اضافة I اضافة G اضافة
+
+372
+00:31:57,800 --> 00:32:02,120
+اقوى C
+
+373
+00:32:02,120 --> 00:32:04,800
+اضافة I اضافة G اضافة اقوى C اضافة I اضافة G اضافة
+
+374
+00:32:04,800 --> 00:32:06,940
+C اضافة I اضافة G اضافة G اضافة C اضافة I اضافة G
+
+375
+00:32:06,940 --> 00:32:07,220
+اضافة G اضافة C اضافة I اضافة G اضافة G اضافة C
+
+376
+00:32:07,220 --> 00:32:07,220
+اضافة I اضافة G اضافة G اضافة C اضافة I اضافة G
+
+377
+00:32:07,220 --> 00:32:08,360
+اضافة G
+
+378
+00:32:11,660 --> 00:32:17,260
+700 اضافة 200 اضافة 100 اضافة 1000 اضافة صحيح؟
+
+379
+00:32:17,260 --> 00:32:22,840
+الثالث حالة 1000
+
+380
+00:32:22,840 --> 00:32:29,500
+اضافة 200 اضافة 1030 اضافة بالضبط 1300 اضافة و
+
+381
+00:32:29,500 --> 00:32:39,240
+بعدها 1600 اضافة لا 600 اضافة 1600 اضافة و الحالة
+
+382
+00:32:39,240 --> 00:32:49,180
+الأخيرةتقريبا 1900 رقم اثنان اثنان اثنان اثنان
+
+383
+00:32:49,180 --> 00:32:49,240
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+384
+00:32:49,240 --> 00:32:57,960
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+385
+00:32:57,960 --> 00:33:02,380
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+386
+00:33:02,380 --> 00:33:02,380
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+387
+00:33:02,380 --> 00:33:02,400
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+388
+00:33:02,400 --> 00:33:02,400
+اثنان اثنان اثنان اثنان اثنان اثنان اثنان اثنان
+
+389
+00:33:02,400 --> 00:33:06,400
+اثنان
+
+390
+00:33:06,400 --> 00:33:13,280
+اثنماذا يحدث عندما Y يكوين أسعار مجموعة؟ بالضبط في
+
+391
+00:33:13,280 --> 00:33:20,660
+1600 ، لذلك الانتجار يحدث عندما يكوين Y يكوين 1600
+
+392
+00:33:20,660 --> 00:33:25,880
+ومجموعة مجموعة يكوين نفس الشيء، لذلك انتجار مجموعة
+
+393
+00:33:25,880 --> 00:33:27,220
+أو أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+394
+00:33:27,220 --> 00:33:27,780
+أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+395
+00:33:27,780 --> 00:33:29,300
+أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+396
+00:33:29,300 --> 00:33:29,920
+أسعار مجموعة أو أسعار مجموعة أو أسعار مجموعة أو
+
+397
+00:33:29,920 --> 00:33:33,420
+أسعار مجموعة أو
+
+398
+00:33:33,420 --> 00:33:40,400
+أسعار مجمY إيقاظ 1200 Is there a positive
+
+399
+00:33:40,400 --> 00:33:44,360
+unplanned inventory change or negative؟ By how
+
+400
+00:33:44,360 --> 00:33:48,060
+much؟ So
+
+401
+00:33:48,060 --> 00:33:56,520
+let's write the question So at Y equals 1200 Is
+
+402
+00:33:56,520 --> 00:34:00,900
+there a negative or positive change in business
+
+403
+00:34:00,900 --> 00:34:06,300
+inventory or inventory change? Yesهو قيمة تغيير
+
+404
+00:34:06,300 --> 00:34:10,980
+البرنامج عن طريق تغيير البرنامج يقوم بالتغيير يقوم
+
+405
+00:34:10,980 --> 00:34:12,080
+بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير
+
+406
+00:34:12,080 --> 00:34:12,680
+يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم
+
+407
+00:34:12,680 --> 00:34:13,560
+بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير
+
+408
+00:34:13,560 --> 00:34:14,560
+يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم
+
+409
+00:34:14,560 --> 00:34:15,000
+بالتغيير يقوم بالتغيير يقوم بالتغيير يقوم بالتغيير
+
+410
+00:34:15,000 --> 00:34:16,580
+يقوم بالتغيير يقوم بالتغير يقوم بالتغير يقوم
+
+411
+00:34:16,580 --> 00:34:25,440
+بالتغير يقوم بالتغير يقوم بالت1300 يعني أقل من 100
+
+412
+00:34:25,440 --> 00:34:31,940
+في هذه الحالة الانفجار المخطط يتخلص أو يتخلص أو
+
+413
+00:34:31,940 --> 00:34:43,660
+يتخلص من 100 على ما يقل 800 هل هناك تندنسية للخروج
+
+414
+00:34:43,660 --> 00:34:54,030
+لتنفع أو لتتخلص؟ من كم؟exactly by 800 مش not صح so
+
+415
+00:34:54,030 --> 00:35:00,910
+the question is suppose at y equals 400 billion
+
+416
+00:35:00,910 --> 00:35:04,710
+dollars or dollars is there a tendency for y to
+
+417
+00:35:04,710 --> 00:35:07,010
+increase or to decrease to reach the equilibrium
+
+418
+00:35:07,010 --> 00:35:12,730
+عشان نوصل التوازن عند 1600 why would or the
+
+419
+00:35:12,730 --> 00:35:15,370
+aggregate income or aggregate output must increase
+
+420
+00:35:15,370 --> 00:35:16,310
+by how much
+
+421
+00:35:23,160 --> 00:35:31,900
+1600 نقص 400 by 1200 صح طيب at 2000 or when y
+
+422
+00:35:31,900 --> 00:35:37,800
+equals 2000 million dollars exactly the y the
+
+423
+00:35:37,800 --> 00:35:42,140
+aggregate output must decline by 400 to reach the
+
+424
+00:35:42,140 --> 00:35:48,580
+equilibrium صحلا من الفين لألف ستمية four hundred
+
+425
+00:35:48,580 --> 00:35:54,320
+to reach the equilibrium صح okay or at the
+
+426
+00:35:54,320 --> 00:35:56,660
+unagreed output level of eight hundred million
+
+427
+00:35:56,660 --> 00:36:00,520
+dollars a billion the disposable income equals
+
+428
+00:36:00,520 --> 00:36:07,680
+what how much Y minus T صح هي at eight hundred قدش
+
+429
+00:36:07,680 --> 00:36:10,800
+ال disposable income اللي هو ال Y دي equals Y
+
+430
+00:36:10,800 --> 00:36:20,970
+minus T so at eight hereAt 8 y equals 800 how much
+
+431
+00:36:20,970 --> 00:36:25,150
+is the disposable income؟ disposable income is yd
+
+432
+00:36:25,150 --> 00:36:32,670
+equals y minus t 800 minus 100 equals 700 this is
+
+433
+00:36:32,670 --> 00:36:35,630
+the disposable income طب how much is the saving in
+
+434
+00:36:35,630 --> 00:36:47,770
+this case؟الحفظ يكون y-c-t فالسؤال هو في y يقل
+
+435
+00:36:47,770 --> 00:36:53,630
+2000 كم هو الحفظ؟
+
+436
+00:36:58,710 --> 00:37:03,430
+Value in Dollars How much is the saving? Saving
+
+437
+00:37:03,430 --> 00:37:13,510
+equals Y minus C minus T So S equals Y 2000 minus
+
+438
+00:37:13,510 --> 00:37:18,210
+The consumption in this case equals how much? 1600
+
+439
+00:37:18,210 --> 00:37:25,710
+minus T T equals 100عن طريق الاستخدام يقوم
+
+440
+00:37:25,710 --> 00:37:31,590
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+441
+00:37:31,590 --> 00:37:33,890
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+442
+00:37:33,890 --> 00:37:36,610
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+443
+00:37:36,610 --> 00:37:37,970
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+444
+00:37:37,970 --> 00:37:39,670
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+445
+00:37:39,670 --> 00:37:42,130
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+446
+00:37:42,130 --> 00:37:44,630
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم
+
+447
+00:37:44,630 --> 00:37:51,670
+باستخدام الاسعار يقوم باستخدام الاسعار يقوم باستof
+
+448
+00:37:51,670 --> 00:37:57,290
+income leakages equals how much leakages equals
+
+449
+00:37:57,290 --> 00:38:01,510
+how much عند aggregate income او عند التوازن
+
+450
+00:38:01,510 --> 00:38:04,930
+leakages equals how much as you know that the
+
+451
+00:38:04,930 --> 00:38:11,670
+leakages equals s plus t صح at equilibrium the
+
+452
+00:38:11,670 --> 00:38:16,090
+leakages leakages
+
+453
+00:38:19,550 --> 00:38:25,030
+اللي هو S plus T صح؟ و ال injections ايش؟ I plus G
+
+454
+00:38:25,030 --> 00:38:29,990
+مصبوح؟ صح؟ So at equilibrium و ال equilibrium عند
+
+455
+00:38:29,990 --> 00:38:36,790
+1600 S plus T equals كدهش؟ Tax equals 100 صح؟ كدهش
+
+456
+00:38:36,790 --> 00:38:40,390
+ال saving؟ We have to calculate saving، saving at
+
+457
+00:38:40,390 --> 00:38:40,990
+equilibrium
+
+458
+00:38:43,920 --> 00:38:50,080
+S Equals Y Minus C Minus T صح؟ So Saving Equals Y
+
+459
+00:38:50,080 --> 00:38:57,960
+Is 1600 Minus C 1300
+
+460
+00:38:57,960 --> 00:39:07,200
+Minus 100 So The Saving Equals How Much 200 Right؟
+
+461
+00:39:07,200 --> 00:39:13,990
+This Is The S So The Leakage Is Leakage Isequals S
+
+462
+00:39:13,990 --> 00:39:19,710
+plus T or equals S two hundred plus taxes one
+
+463
+00:39:19,710 --> 00:39:25,150
+hundred so equals three hundred billion dollars صح
+
+464
+00:39:25,150 --> 00:39:31,490
+طب كدهش ال injections I plus G so at equilibrium
+
+465
+00:39:31,490 --> 00:39:35,170
+طبعا at equilibrium leakages must equal injections
+
+466
+00:39:35,170 --> 00:39:42,710
+exactly so I200 plus G 100 So at equilibrium
+
+467
+00:39:42,710 --> 00:39:48,350
+leakages equals injections صح؟ Injections صح؟ So
+
+468
+00:39:48,350 --> 00:39:54,070
+the injection is I plus G equals 200 plus 100
+
+469
+00:39:54,070 --> 00:40:03,290
+Right؟ Okay Let's go to this exercise
+
+470
+00:40:11,500 --> 00:40:18,320
+كما تشاهدين الـ C يقل .. او الاقتصاد الإيطالي يمكن
+
+471
+00:40:18,320 --> 00:40:25,720
+ان يكون مصمم من المقارنة او المقارنة C يقل 300 C
+
+472
+00:40:25,720 --> 00:40:34,100
+يقل 300 plus 0.8 YD، صحيح؟ ومقارنتة الحكومة يقل G
+
+473
+00:40:34,100 --> 00:40:41,360
+يقل 400 مليون دولار تي تاكسيأو 200 مليون دولار
+
+474
+00:40:41,360 --> 00:40:46,780
+وإستخدام المخطط يكون 200 مليون دولار.السؤال هو
+
+475
+00:40:46,780 --> 00:40:55,570
+أولا، مستوى الإيقال للإيقاع الإيطالي هو كم؟لذلك
+
+476
+00:40:55,570 --> 00:40:59,910
+يجب أن نقوم بالتخطيط للمستوى الإيقاليبيومي لجهة
+
+477
+00:40:59,910 --> 00:41:02,410
+الـ Aggregate Output في المستوى الإيقاليبيويمي كما
+
+478
+00:41:02,410 --> 00:41:05,130
+تعلمين Y يقوم بالتخطيط لجهة الـ Aggregate
+
+479
+00:41:05,130 --> 00:41:09,750
+Expenditure لذلك Y يقوم بالتخطيط لـ C Plus I Plus
+
+480
+00:41:09,750 --> 00:41:19,370
+G لذلك Y يقوم بالتخطيط لـ C 300 Plus 0.8 Y D Plus
+
+481
+00:41:19,370 --> 00:41:33,040
+I200 plus g 400 right so y equals 300 plus 0.8
+
+482
+00:41:33,040 --> 00:41:41,300
+times yd is y minus t صح so y minus t is given the
+
+483
+00:41:41,300 --> 00:41:47,180
+tax the net tax is given so equals 200 plus 200
+
+484
+00:41:47,180 --> 00:41:57,490
+plus 400 صحSo Y equals 300 plus 200 plus 400
+
+485
+00:41:57,490 --> 00:42:09,930
+equals 900 plus 0.8Y minus 0.8 times 200 equals
+
+486
+00:42:09,930 --> 00:42:10,630
+160
+
+487
+00:42:13,290 --> 00:42:20,730
+مصبوح؟ So اعمل shifting هيك Y minus 0.8Y equals
+
+488
+00:42:20,730 --> 00:42:30,690
+900 minus 160 equals how much? 740 So this is one
+
+489
+00:42:30,690 --> 00:42:41,470
+0.2Y equals 740 So how much is Y? So Y equals
+
+490
+00:42:46,570 --> 00:42:56,350
+740 over 0.2 صح؟ So Y equals how much؟ That's it
+
+491
+00:42:56,350 --> 00:43:01,950
+B, the answer is B Right؟ How much is the
+
+492
+00:43:01,950 --> 00:43:05,230
+consumption in this case؟ Because that's a direct
+
+493
+00:43:05,230 --> 00:43:14,760
+substitution So C Yes أمسح هذا؟Okay, so calculate
+
+494
+00:43:14,760 --> 00:43:17,320
+the consumption, the aggregate consumption in this
+
+495
+00:43:17,320 --> 00:43:25,960
+case C equals 300 plus 0.8 times YD So, C equals
+
+496
+00:43:25,960 --> 00:43:31,660
+300 plus 0.8 times Y at equilibrium equals how
+
+497
+00:43:31,660 --> 00:43:44,270
+much? 3700 minus T, T equals how much?200 so C
+
+498
+00:43:44,270 --> 00:43:56,150
+equals 300 plus 0.8 times 3000 700 minus 200 3500
+
+499
+00:43:56,150 --> 00:44:04,530
+so C equals 300 plus how much the 0.8 times اعمله
+
+500
+00:44:04,530 --> 00:44:09,890
+مع الاهلة شوفوا how much
+
+501
+00:44:11,690 --> 00:44:18,970
+Okay two thousand eight hundred so c equals three
+
+502
+00:44:18,970 --> 00:44:23,010
+hundred three thousand one hundred billion dollars
+
+503
+00:44:23,010 --> 00:44:28,790
+so So as you see here the consumption equals how
+
+504
+00:44:28,790 --> 00:44:32,670
+much three thousand one hundred so the answer is a
+
+505
+00:44:32,670 --> 00:44:35,210
+right يعطيكم العشري
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/GgNFKCYu3tE.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/GgNFKCYu3tE.srt
new file mode 100644
index 0000000000000000000000000000000000000000..05d120ac9885a4761c2ca0f96c9190dba7978982
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/GgNFKCYu3tE.srt
@@ -0,0 +1,1968 @@
+1
+00:00:21,020 --> 00:00:24,340
+Okay, بسم الله الرحمن الرحيم اليوم إن شاء الله
+
+2
+00:00:24,340 --> 00:00:29,100
+سنبدأ بمعرفة الـ macro economics كما ذكرنا عندما 
+
+3
+00:00:29,100 --> 00:00:32,900
+نقدر 
+
+4
+00:00:32,900 --> 00:00:33,760
+ 
+5
+00:00:33,760 --> 00:00:34,240
+ 
+6
+00:00:34,240 --> 00:00:37,040
+ 
+7
+00:00:37,040 --> 00:00:38,900
+ 
+8
+00:00:38,900 --> 00:00:42,720
+ 
+9
+00:00:43,380 --> 00:00:50,580
+مثل مصطلحات الإنتاج والإنتاج والإنتاج والإنتاج
+
+10
+00:00:50,580 --> 00:00:54,760
+الإنتاج والإنتاج والإنتاج والإنتاج والإنتاج والإنتاج
+
+11
+00:00:54,760 --> 00:00:56,120
+الإنتاج والإنتاج والإنتاج والإنتاج والإنتاج والإنتاج
+
+12
+00:00:56,120 --> 00:00:56,580
+الإنتاج والإنتاج والإنتاج والإنتاج والإنتاج والإنتاج
+
+13
+00:00:56,580 --> 00:00:56,880
+الإنتاج والإنتاج والإنتاج والإنتاج والإنتاج والإنتاج
+
+14
+00:00:56,880 --> 00:00:56,920
+الإنتاج والإنتاج والإنتاج والإنتاج والإنتاج والإنتاج
+
+15
+00:00:56,920 --> 00:01:04,580
+الإنتاج والإنتاج والإنتاج والإنتاج والإنتاج والإنتاج
+
+16
+00:01:04,580 --> 00:01:07,580
+الإنتاج والإنتاج والإنتاج
+
+17
+00:01:10,990 --> 00:01:17,650
+وهذه الحلقة تتكلم عن بعض التصريحات وبعض المصادر
+
+18
+00:01:17,650 --> 00:01:20,830
+المرتبطة بالـ microeconomics وهو تقريبا 
+
+19
+00:01:20,830 --> 00:01:22,910
+ 
+
+20
+00:01:22,910 --> 00:01:25,510
+ 
+
+21
+00:01:25,510 --> 00:01:25,950
+ 
+
+22
+00:01:25,950 --> 00:01:25,970
+ 
+
+23
+00:01:25,970 --> 00:01:29,530
+ 
+
+24
+00:01:29,530 --> 00:01:37,070
+تقريباً
+
+25
+00:01:38,900 --> 00:01:45,560
+أو تدرس الفرق بين الاقتصاد الكلي الذي يركز على
+
+26
+00:01:45,560 --> 00:01:56,260
+حركة الإنسان والعمل والعائلات والاقتصاد الكلي
+
+27
+00:01:56,260 --> 00:02:00,800
+الذي يركز على حركة الإنسان والعائلات والاقتصاد 
+
+28
+00:02:00,800 --> 00:02:06,620
+الكلي، لذلك دعونا نبدأ بالفرق بين الـ micro و
+
+29
+00:02:06,620 --> 00:02:11,060
+macro economics كما ترى الـ micro economics تجارب
+
+30
+00:02:11,060 --> 00:02:14,660
+عوامل الاختصارات الاقتصادية
+
+31
+00:02:18,980 --> 00:02:22,620
+الشركات والعائلات لذلك في الـ microeconomics كما 
+
+32
+00:02:22,620 --> 00:02:27,100
+تعلمين أننا قد ذكرنا أننا قد دراسة  الجزء من
+
+33
+00:02:27,100 --> 00:02:32,340
+المجالات الانفصالية في الاقتصاد، لكن في 
+
+34
+00:02:32,340 --> 00:02:37,080
+الـ microeconomics، الـ microeconomics تجارب الجزء 
+
+35
+00:02:37,080 --> 00:02:41,530
+التجريبي من أو تتعامل مع الاقتصاد بالنسبة للجمهور
+
+36
+00:02:41,530 --> 00:02:44,290
+بشكل كامل، فهو يتعامل مع الإنتاج الإنتاجي
+
+37
+00:02:44,290 --> 00:02:47,690
+الإنتاجي الإنتاجي الإنتاجي الإنتاجي الإنتاجي
+
+38
+00:02:47,690 --> 00:02:50,530
+الإنتاجي الإنتاجي الإنتاجي الإنتاجي الإنتاجي
+
+39
+00:02:50,530 --> 00:02:51,250
+الإنتاجي الإنتاجي الإنتاجي الإنتاجي الإنتاجي
+
+40
+00:02:51,250 --> 00:02:55,990
+الإنتاجي الإنتاجي الإنتاجي الإنتاجي الإنتاجي
+
+41
+00:02:55,990 --> 00:02:58,730
+الإنتاجي الإنتاجي الإنتاجي الإنتاجي ال
+
+42
+00:02:59,580 --> 00:03:03,660
+الحياة في الاقتصاد، صحيح؟ لذلك الـ Aggregate
+
+43
+00:03:03,660 --> 00:03:07,520
+Behavior ماذا؟ يتفضل إلى الحياة لجميع الكائنات
+
+44
+00:03:07,520 --> 00:03:14,440
+ومؤسسات مع بعض، صحيح؟ لذلك، لسنا نتكلم عن الشخص،
+
+45
+00:03:14,440 --> 00:03:20,920
+لكننا نتكلم عن هذه المجالات كمجموعة، الكائنات،
+
+46
+00:03:20,920 --> 00:03:27,040
+الحياة لجميع الكائنات، الحياة لجميع الأشخاص، صحيح؟
+
+47
+00:03:27,040 --> 00:03:29,220
+كمجموعة، لذلك
+
+48
+00:03:31,950 --> 00:03:40,070
+لنذهب إلى أسلوب المدارس المدارس المدارس يعني
+
+49
+00:03:40,070 --> 00:03:46,850
+جذور المدارس المدارس في هذه الحالة سندرس 
+
+50
+00:03:46,850 --> 00:03:54,260
+اتجاهين في الاقتصاد، الأول هو النظر الكلاسيكي أو
+
+51
+00:03:54,260 --> 00:03:58,880
+المدارس الكلاسيكية للاقتصاد الاقتصادي ونظر الكينزية
+
+52
+00:03:58,880 --> 00:04:04,300
+كيف عاملوا التعامل مع الاقتصاد الاقتصادي أو 
+
+53
+00:04:04,300 --> 00:04:06,320
+الاقتصاد الكلي أو الاقتصاد الكلي أو 
+
+54
+00:04:06,320 --> 00:04:07,840
+الاقتصاد الكلي أو الاقتصاد الكلي أو 
+
+55
+00:04:07,840 --> 00:04:09,280
+الاقتصاد الكلي أو الاقتصاد الكلي أو
+
+56
+00:04:09,280 --> 00:04:11,020
+الاقتصاد الكلي أو الاقتصاد الكلي أو
+
+57
+00:04:11,020 --> 00:04:11,600
+الاقتصاد الكلي أو الاقتصاد الكلي أو
+
+58
+00:04:11,600 --> 00:04:12,280
+الاقتصاد الكلي أو الاقتصاد الكلي أو
+
+59
+00:04:12,280 --> 00:04:13,500
+الاقتصاد الكلي أو الاقتص
+
+60
+00:04:33,920 --> 00:04:38,720
+النظرية الجزئية على القضايا الاقتصادية الكلية
+
+61
+00:04:42,160 --> 00:04:45,880
+وقالوا إن التجارة تتجرى تتجرى تتجرى تتجرى 
+
+62
+00:04:45,880 --> 00:04:50,080
+تتجرى تتجرى تتجرى تتجرى تتجرى تتجرى تتجرى
+
+63
+00:04:50,080 --> 00:04:50,120
+تتجرى تتجرى تتجرى تتجرى تتجرى تتجرى تتجرى
+
+64
+00:04:50,120 --> 00:04:50,200
+تتجرى تتجرى تتجرى تتجرى تتجرى تتجرى تتجرى
+
+65
+00:04:50,200 --> 00:04:51,020
+تتجرى تتجرى تتجرى تتجرى تتجرى تتجرى تتجرى
+
+66
+00:04:51,020 --> 00:04:53,000
+تتجرى تتجرى تتجرى تتجرى تتجرى تتجرى تتجرى
+
+67
+00:04:53,000 --> 00:05:10,360
+تتجرى تتجرى تتجرى تتجار
+
+68
+00:05:11,970 --> 00:05:19,510
+هذا يعني إذا كانت الشركة أو الشركات أو الشركات 
+
+69
+00:05:19,510 --> 00:05:26,350
+تصنع أو تصنع بضائع وخدمات كل هذه البضائع ستكون
+
+70
+00:05:26,350 --> 00:05:32,090
+مُباعة، صح؟ لذلك إذا كانت الشركات تصنع 
+
+71
+00:05:38,930 --> 00:05:47,530
+كل الإنتاج تباع تنبع كل الإنتاج تباع
+
+72
+00:05:47,530 --> 00:05:56,710
+تنبع كل الإنتاج تنبع كل الإنتاج تنبع كل الإنتاج
+
+73
+00:05:56,710 --> 00:05:58,110
+تنبع كل الإنتاج تنبع كل الإنتاج تنبع كل الإنتاج
+
+74
+00:05:58,110 --> 00:05:58,150
+تنبع كل الإنتاج تنبع كل الإنتاج تنبع كل الإنتاج
+
+75
+00:05:58,150 --> 00:05:58,210
+تنبع كل الإنتاج تنبع كل الإنتاج تنبع كل الإنتاج
+
+76
+00:05:58,210 --> 00:05:59,810
+تنبع كل الإنتاج تنبع كل الإنتاج تنبع كل الإنتاج
+
+77
+00:05:59,810 --> 00:06:05,170
+تنبع كل 
+
+78
+00:06:05,170 --> 00:06:07,830
+الإنتاج تنبع كل ال
+
+79
+00:06:12,240 --> 00:06:17,220
+حسنًا، للأسف، خلال
+
+80
+00:06:17,220 --> 00:06:23,940
+مرحلة الكساد العظيم، مرحلة الكساد العظيم مصطلحات
+
+81
+00:06:23,940 --> 00:06:28,560
+كثيرة تُصنع مصطلحات كثيرة تُصنع مصطلحات كثيرة تُصنع
+
+82
+00:06:28,560 --> 00:06:30,300
+مصطلحات كثيرة تُصنع مصطلحات كثيرة تُصنع مصطلحات
+
+83
+00:06:30,300 --> 00:06:33,740
+كثيرة تُصنع مصطلحات كثيرة تُصنع مصطلحات كثيرة تُصنع
+
+84
+00:06:33,740 --> 00:06:34,680
+مصطلحات كثيرة تُصنع مصطلحات كثيرة تُصنع مصطلحات
+
+85
+00:06:34,680 --> 00:06:36,120
+كثيرة تُصنع مصطلحات كثيرة تُصنع مصطلحات كثيرة تُصنع
+
+86
+00:06:36,120 --> 00:06:42,000
+مصطلحات كثيرة تُصنع مصطلحات وكل الإنتاج اللي ..
+
+87
+00:06:42,000 --> 00:06:47,580
+اللي .. اللي أنتجوها لم تُباع So, in this case, the
+
+88
+00:06:47,580 --> 00:06:54,780
+classical economist failed to explain the reasons
+
+89
+00:06:54,780 --> 00:07:02,440
+for this .. their theory Yes Yes, we are coming to
+
+90
+00:07:02,440 --> 00:07:10,670
+this point Yes، لذلك، دعنا نذهب أولًا إلى فكرة أو
+
+91
+00:07:10,670 --> 00:07:17,090
+نظرية الاقتصادي الكلاسيكي عن سوق العمل دعنا نذهب 
+
+92
+00:07:17,090 --> 00:07:22,730
+إلى تحقيق سوق العمل بحسب النظرية الكلاسيكية ومن ثم 
+
+93
+00:07:22,730 --> 00:07:27,810
+النظرية الكينزية، صحيح؟ لذلك، دعنا نذهب إلى نظرية
+
+94
+00:07:27,810 --> 00:07:33,970
+كلاسيكية عن سوق العمل كما ذكرنا في الاقتصادي 
+
+95
+00:07:33,970 --> 00:07:41,590
+الكلاسيكي، الإتزان في السوق يحدث عندما يتعادل
+
+96
+00:07:41,590 --> 00:07:48,890
+العرض أو يتجاوز مستوى العرض أو 
+
+97
+00:07:48,890 --> 00:07:53,070
+يتجاوز مستوى العرض أو يتجاوز مستوى العرض أو يتجاوز
+
+98
+00:07:53,070 --> 00:07:58,930
+مستوى العرض العرض العرض العرض العرض العرض العرض
+
+99
+00:07:58,930 --> 00:07:59,070
+العرض العرض العرض العرض العرض العرض العرض العرض
+
+100
+00:07:59,070 --> 00:07:59,150
+العرض العرض العرض العرض العرض العرض العرض العرض
+
+101
+00:07:59,150 --> 00:08:04,150
+العرض العرض العرض الع
+
+102
+00:08:04,870 --> 00:08:10,220
+الفكرة في سوق العمل هي نفسها، هي تشبه كثيرًا 
+
+103
+00:08:10,220 --> 00:08:15,420
+فكرة الإتزان في سوق العمل هي تشبه كثيرًا 
+
+104
+00:08:15,420 --> 00:08:16,860
+فكرة الإتزان في سوق العمل في سوق العمل 
+
+105
+00:08:16,860 --> 00:08:17,480
+في سوق العمل في سوق العمل في سوق العمل في
+
+106
+00:08:17,480 --> 00:08:24,720
+سوق العمل في سوق العمل في سوق العمل في 
+
+107
+00:08:24,720 --> 00:08:25,200
+سوق العمل في سوق العمل في سوق العمل في السوق
+
+108
+00:08:25,200 --> 00:08:28,140
+العمل في سوق العمل في سوق العمل في سوق العمل في
+
+109
+00:08:28,140 --> 00:08:28,640
+سوق العمل في سوق العمل في سوق العمل في سوق
+
+110
+00:08:28,640 --> 00:08:28,880
+العمل في سوق العمل في سوق العمل في سوق
+
+111
+00:08:28,880 --> 00:08:29,800
+العمل في سوق العمل في سوق العمل في سوق
+
+112
+00:08:29,800 --> 00:08:34,400
+العمل في سوق العمل في سوق العمل في سوق
+
+113
+00:08:34,400 --> 00:08:36,940
+العمل
+
+114
+00:08:38,530 --> 00:08:48,270
+وهذا هو عرض العمل عرض العمل وعرض العمل عرض
+
+115
+00:08:48,270 --> 00:08:52,030
+العمل
+
+116
+00:08:52,030 --> 00:08:55,930
+عرض العمل عرض العمل عرض العمل عرض العمل
+
+117
+00:08:55,930 --> 00:09:00,480
+عرض العمل عرض العمل، والطلب على العمل لديه نقاط
+
+118
+00:09:00,480 --> 00:09:02,380
+نقاط 
+
+119
+00:09:02,380 --> 00:09:05,360
+ 
+
+120
+00:09:05,360 --> 00:09:06,000
+ 
+
+121
+00:09:06,000 --> 00:09:08,500
+ 
+
+122
+00:09:08,500 --> 00:09:10,920
+ 
+
+123
+00:09:10,920 --> 00:09:17,580
+ 
+
+124
+00:09:17,580 --> 00:09:22,960
+ 
+
+125
+00:09:22,960 --> 00:09:30,880
+عندما تتعادل عرض العمل، تكون هناك إتزان 
+
+126
+00:09:30,880 --> 00:09:36,140
+في سوق العمل، فهنا لدينا إتزان في سوق
+
+127
+00:09:36,140 --> 00:09:43,860
+العمل، فهذا هو سعر العمل، PL أو السعر، أسعار
+
+128
+00:09:43,860 --> 00:09:52,300
+العمل هو السعر للعمالة، فهذا هو السعر، وهي كمية
+
+129
+00:09:52,300 --> 00:09:57,600
+العمل أو عدد العمال، صحيح؟ حسنًا، بالنسبة للنظر
+
+130
+00:09:57,600 --> 00:10:00,660
+الكلاسيكي، 
+
+131
+00:10:00,660 --> 00:10:06,700
+قالوا إن سوق العمل دائمًا واضح، هذا يعني أن
+
+132
+00:10:06,700 --> 00:10:11,900
+سوق العمل في إتزان، دائمًا سوق العمل في
+
+133
+00:10:11,900 --> 00:10:17,980
+حالة توظيف كامل وحالة توازن، صحيح؟ لذلك، اعتبروا 
+
+134
+00:10:17,980 --> 00:10:18,560
+نظر الكلاسيكي
+
+135
+00:10:23,390 --> 00:10:28,630
+assume that the labor market is always clear clear
+
+136
+00:10:28,630 --> 00:10:32,890
+means it's in equilibrium دائماً في حالة توازن and
+
+137
+00:10:32,890 --> 00:10:37,370
+we have a full employment there is no unemployment
+
+138
+00:10:37,370 --> 00:10:42,610
+in the labor market and they assume that suppose
+
+139
+00:10:42,610 --> 00:10:48,530
+that the labor demand declined إذا افترضوا أن
+
+140
+00:10:48,530 --> 00:10:54,120
+there is a decline in the labor demand، لذلك يوجد تحويل 
+
+141
+00:10:54,120 --> 00:10:59,180
+تجارب مجموعات العمل تحويل
+
+142
+00:10:59,180 --> 00:11:04,640
+تجارب
+
+143
+00:11:04,640 --> 00:11:06,200
+مجموعات العمل تحويل تجارب مجموعة العمل تحويل تجارب
+
+144
+00:11:06,200 --> 00:11:06,400
+مجموعة العمل تحويل تجارب مجموعة العمل تحويل تجارب
+
+145
+00:11:06,400 --> 00:11:06,800
+مجموعة العمل تحويل تجارب مجموعة العمل تحويل تجارب
+
+146
+00:11:06,800 --> 00:11:07,420
+مجموعة العمل تحويل تجارب مجموعة العمل تحويل تجارب
+
+147
+00:11:07,420 --> 00:11:10,240
+مجموعة العمل تحويل تجارب مجموعة العمل تحويل تجارب
+
+148
+00:11:10,240 --> 00:11:17,120
+مجموعة العمل تحويل تحويل تجارب
+
+149
+00:11:17,120 --> 00:11:22,850
+مجموعة العمل تحويل لدينا مقاومة جديدة من الـ A1
+
+150
+00:11:22,850 --> 00:11:30,670
+إلى الـ A2 هذا يعود إلى تقليل العمل من L0 إلى L1
+
+151
+00:11:30,670 --> 00:11:40,690
+كما ترى والعيارات ستتخلص ويعتمدون
+
+152
+00:11:40,690 --> 00:11:49,200
+إذا كانت العيارة مستمرة في W0 قال لك إذا الأجور
+
+153
+00:11:49,200 --> 00:11:57,000
+ضالتها ثابتة و W لا في هذه الحالة ماذا سيحدث؟ في
+
+154
+00:11:57,000 --> 00:12:03,740
+هذه الحالة، هذا هو الـ Quant of Labor Demand صح؟ و
+
+155
+00:12:03,740 --> 00:12:07,160
+هذا هو Quant of Labor Supply فQuant of Labor
+
+156
+00:12:07,160 --> 00:12:11,920
+Supply أكبر من Quant of Labor Demand Quant of
+
+157
+00:12:11,920 --> 00:12:15,200
+Labor Supply بأن عرض عمال أكبر من الطلب على 
+
+158
+00:12:15,200 --> 00:12:19,240
+العمال، فهناك ماذا؟ unemployment عندنا حالة 
+
+159
+00:12:19,240 --> 00:12:27,800
+بطالة So they assume that if the wages are or
+
+160
+00:12:27,800 --> 00:12:35,300
+remain constant at w not in this case the quantity
+
+161
+00:12:35,300 --> 00:12:39,740
+of labor demanded as a point on the labor demand
+
+162
+00:12:39,740 --> 00:12:43,900
+curve is larger than the quantity supplied of
+
+163
+00:12:43,900 --> 00:12:49,480
+labor or quantity of labor supplied هي أكثر من قيمة
+
+164
+00:12:49,480 --> 00:12:54,840
+العمل المطلوبة لذلك نحن لدينا ماذا؟ نحن لدينا عملية
+
+165
+00:12:54,840 --> 00:13:02,880
+غير مجتمعة تلصق هنا هذا الترانجل تلصق عمر العملية 
+
+166
+00:13:02,880 --> 00:13:08,080
+غير مجتمعة أو قيمة العملية غير مجتمعة لذلك إذا كان
+
+167
+00:13:08,080 --> 00:13:10,840
+عملية العملية غير مجتمعة أو قيمة العملية غير مجتمعة
+
+168
+00:13:10,840 --> 00:13:14,080
+تلصق عملية غير مجتمعة تلصق عملية غير مجتمعة تلصق
+
+169
+00:13:14,080 --> 00:13:17,060
+عملية غير مجتمعة تلصق عملية غير مجتمعة تلصق عملية
+
+170
+00:13:17,060 --> 00:13:21,040
+غير مجتمعة تلصق عملية غير مجتمعة تلصق شخص من العاملين
+
+171
+00:13:21,040 --> 00:13:26,360
+الذي لم يعمل سيقبل أن يعمل مع عيارات أقل كما ترى
+
+172
+00:13:26,360 --> 00:13:32,460
+إذا كان هناك عدد عمل عالي فشخص من العاملين الذي لم
+
+173
+00:13:32,460 --> 00:13:38,400
+يعمل سيقبل أن يعمل مع عيارات أقل سيقبلون أنه إذا
+
+174
+00:13:38,400 --> 00:13:41,740
+في عنا بطالة سيقبلون أننا نشتغل بأجور أقل،
+
+175
+00:13:41,740 --> 00:13:47,100
+مظلوم ولا لأ؟ لذلك، هذا يدفع إلى تقليل العيارات
+
+176
+00:13:51,770 --> 00:13:59,090
+في هذه الحالة، ستتخلص السعر لتصل إلى W1 من W0 إلى
+
+177
+00:13:59,090 --> 00:14:07,630
+W1. لذلك، يعتمدون على أن السعر أو السعر مرتبط أو
+
+178
+00:14:07,630 --> 00:14:14,350
+مرتبط. و .. نعم .. لماذا؟
+
+179
+00:14:16,100 --> 00:14:20,800
+حسنًا حسنًا ولكن اعتبارنا أو اعتبارهم هو أننا 
+
+180
+00:14:20,800 --> 00:14:25,300
+لدينا عدد عملي كبير صحيح؟ هذا عدد عملي كبير صحيح
+
+181
+00:14:25,300 --> 00:14:30,020
+يدفع إلى ماذا؟ يدفع إلى تقليل العمليات لأن جزء
+
+182
+00:14:30,020 --> 00:14:34,220
+منهم أو جزء من هذه العملية سيقبل العمل مع عمليات
+
+183
+00:14:34,220 --> 00:14:39,880
+أقل حسنًا لكن .. و بعد ذلك هذا يدفع إلى ماذا؟ إلى
+
+184
+00:14:39,880 --> 00:14:43,440
+تقليل العمليات صحيح؟
+
+185
+00:14:47,690 --> 00:14:53,550
+وهذا هو الفرق الانتاج يتم حلله لذلك لتخلص من
+
+186
+00:14:53,550 --> 00:15:02,150
+الانتاج الواجهات تتخلص بدون أي تدخل من الحكومة
+
+187
+00:15:02,150 --> 00:15:07,550
+لذلك يعتمدون على أنه لا يوجد بحاجة لتدخل الحكومة
+
+188
+00:15:07,550 --> 00:15:10,950
+لأنه
+
+189
+00:15:10,950 --> 00:15:19,470
+تلقائيًا الواجهات تتخلص بالعكس بالتأكيد هم يعتمدون
+
+190
+00:15:19,470 --> 00:15:26,270
+أنه إذا كان هناك 
+
+191
+00:15:26,270 --> 00:15:33,270
+زيادة في مطالبة العمل هذا هو مصادر العمل 1 مطالبة
+
+192
+00:15:33,270 --> 00:15:42,150
+العمل 1 وهذا E1 مطالبة العمل 1 QLD1
+
+193
+00:15:44,290 --> 00:15:48,770
+طبعا هنا as you see the value of unemployment is
+
+194
+00:15:48,770 --> 00:15:59,190
+QLS minus QLD sorry yes الذي هو L0 minus L1 this
+
+195
+00:15:59,190 --> 00:16:03,310
+is the value or the gap between or the difference
+
+196
+00:16:03,310 --> 00:16:05,350
+between quantitative labor supply and quantitative
+
+197
+00:16:05,350 --> 00:16:08,250
+labor demand this is the value of unemployment
+
+198
+00:16:08,250 --> 00:16:14,820
+right والآن اعترض أن العمل المطلوب ارتكب ارتكاب
+
+199
+00:16:14,820 --> 00:16:18,740
+ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب
+
+200
+00:16:18,740 --> 00:16:18,920
+ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب
+
+201
+00:16:18,920 --> 00:16:19,060
+ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب
+
+202
+00:16:19,060 --> 00:16:20,300
+ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب
+
+203
+00:16:20,300 --> 00:16:23,940
+ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب
+
+204
+00:16:23,940 --> 00:16:24,400
+ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب ارتكاب
+
+205
+00:16:24,400 --> 00:16:40,560
+ارتكاب ارتك
+
+206
+00:16:41,210 --> 00:16:45,930
+هناك تغيير كلمة صحيح للطاقة العملية المطلوبة هذا
+
+207
+00:16:45,930 --> 00:16:51,410
+يؤدي إلى نقطة اتزان جديدة من A1 إلى A2 التي
+
+208
+00:16:51,410 --> 00:16:58,990
+يؤدي إلى زيادة العمليات من W1 إلى W2، صحيح؟ لذلك،
+
+209
+00:16:58,990 --> 00:17:07,360
+يعتمدون على أن العمليات مطلوبة، و لدينا market
+
+210
+00:17:07,360 --> 00:17:14,140
+clearing market clearing يعني أن الmarket دائما في
+
+211
+00:17:14,140 --> 00:17:17,620
+حالة
+
+212
+00:17:17,620 --> 00:17:23,760
+توظيف كامل وحالة توازن full employment إذا كانت
+
+213
+00:17:23,760 --> 00:17:30,240
+الأجور مستمرة في W1 ماذا يحدث؟ يعني لو بدأنا نفترض
+
+214
+00:17:30,240 --> 00:17:34,640
+أن الأجور ظلت جامدة وفق لنظرية الذي هم ال classic
+
+215
+00:17:35,500 --> 00:17:41,460
+Suppose أن الأجور لم تزدد would not increase
+
+216
+00:17:41,460 --> 00:17:49,340
+to W2 Suppose that the wages remain constant at W1
+
+217
+00:17:49,340 --> 00:17:52,780
+What would happen؟ In this case, the quant of
+
+218
+00:17:52,780 --> 00:17:55,800
+labor demanded as you see which is a point along
+
+219
+00:17:55,800 --> 00:17:59,900
+the labor demand curve 2 is larger than the quant
+
+220
+00:17:59,900 --> 00:18:04,180
+of labor supplied This is a QLD وهذا .. this is a
+
+221
+00:18:04,180 --> 00:18:09,620
+QLS صح؟ So in this case, the quota of labor
+
+222
+00:18:09,620 --> 00:18:17,740
+demanded QLD is larger than QLS The number of or
+
+223
+00:18:17,740 --> 00:18:20,340
+the quota of labor demanded الكمية المطلوبة من
+
+224
+00:18:20,340 --> 00:18:22,620
+العمال أو العدد المطلوب من العمال أكبر من العدد
+
+225
+00:18:22,620 --> 00:18:26,720
+المعروض من العمال So this leads to what? Directly,
+
+226
+00:18:26,940 --> 00:18:30,380
+this leads to increasing the wages لأن في عنده طلب
+
+227
+00:18:30,380 --> 00:18:33,340
+كثير على العمال، مظبوط؟ According to their
+
+228
+00:18:33,340 --> 00:18:39,790
+assumption إذا كان العدد المطلوب من العمال أكبر من
+
+229
+00:18:39,790 --> 00:18:40,650
+عدد العمال المطلوب من العمال المطلوب من العمال
+
+230
+00:18:40,650 --> 00:18:41,350
+المطلوب من العمال المطلوب من العمال المطلوب من
+
+231
+00:18:41,350 --> 00:18:43,590
+العمال المطلوب من العمال المطلوب من العمال المطلوب
+
+232
+00:18:43,590 --> 00:18:44,250
+من العمال
+
+233
+00:18:48,240 --> 00:18:56,760
+عندما نزل العمليات و نزل العمليات من W1 إلى W2 ، فسنصل
+
+234
+00:18:56,760 --> 00:19:04,160
+إلى نقطة new equilibrium E2 لكي نخلق فرق ما بين
+
+235
+00:19:04,160 --> 00:19:06,920
+المساعدة الكوانتوم والمساعدة الكوانتوم
+
+236
+00:19:10,520 --> 00:19:17,120
+أو اتجارات العمل أو اتجارات العمل أو اتجارات العمل
+
+237
+00:19:17,120 --> 00:19:20,560
+أو اتجارات العمل أو اتجارات العمل اتجارة العمل
+
+238
+00:19:20,560 --> 00:19:20,620
+العمل اتجارة العمل اتجارة العمل اتجارة العمل
+
+239
+00:19:20,620 --> 00:19:20,680
+اتجارة العمل اتجارة العمل اتجارة العمل اتجارة
+
+240
+00:19:20,680 --> 00:19:22,480
+العمل اتجارة العمل اتجارة العمل اتجارة العمل
+
+241
+00:19:22,480 --> 00:19:25,940
+اتجارة العمل اتجارة العمل اتجارة العمل اتجارة
+
+242
+00:19:25,940 --> 00:19:28,840
+العمل اتجارة العمل اتجارة العمل اتجارة العمل
+
+243
+00:19:28,840 --> 00:19:30,960
+اتجارة العمل اتجارة العمل اتجارة العمل اتجارة
+
+244
+00:19:32,300 --> 00:19:35,460
+According to the classical view summary طبعًا أن
+
+245
+00:19:35,460 --> 00:19:38,400
+according to the classical view they assume that
+
+246
+00:19:38,400 --> 00:19:45,900
+the wages are elastic right it's not sticky ال
+
+247
+00:19:45,900 --> 00:19:51,400
+wage غير sticky غير جامد right if the labor demand
+
+248
+00:19:51,400 --> 00:19:57,310
+increased لدينا نقطة اتزان جديدة و لدينا عيارات
+
+249
+00:19:57,310 --> 00:20:01,870
+جديدة و كمية العمل المطلوبة ستزال تزل تزل تزل
+
+250
+00:20:01,870 --> 00:20:04,630
+تزل تزل تزل
+
+251
+00:20:08,870 --> 00:20:12,630
+وهو يقوم بتحفيز مستوى مدى الناس؟ نعم بالنسبة للنظر
+
+252
+00:20:12,630 --> 00:20:17,390
+العلمي نعم ولكننا سنرى بالنسبة للوقت الكهرباء
+
+253
+00:20:17,390 --> 00:20:19,710
+الكهرباء الكهرباء الكهرباء الكهرباء الكهرباء الكهرباء
+
+254
+00:20:19,710 --> 00:20:20,370
+الكهرباء الكهرباء الكهرباء الكهرباء الكهرباء الكهرباء
+
+255
+00:20:20,370 --> 00:20:23,310
+الكهرباء الكهرباء الكهرباء الكهرباء الكهرباء كهرباء
+
+256
+00:20:23,310 --> 00:20:25,790
+كهرباء كهرباء كهرباء كهرباء كهرباء كهرباء كهرباء كهرباء
+
+257
+00:20:25,790 --> 00:20:26,630
+كهرباء كهرباء كهرباء كهرباء كهرباء كهرباء كهرباء كهرباء
+
+258
+00:20:26,630 --> 00:20:35,350
+كهرباء كهرباء كهرباء كهرباء كهرباء كهرباء كهرباء كهرباء
+
+259
+00:20:35,350 --> 00:20:44,660
+كنعم ولكنني سأشرح شيء مرتبط بالتحرير
+
+260
+00:20:44,660 --> 00:20:51,340
+الكبير لكي أشرح الفكرة كمجموعة في التفاصيل أنا
+
+261
+00:20:51,340 --> 00:20:56,980
+قادم إلى هذا الموضوع يا عمجل هل من الواضح؟ فهم
+
+262
+00:20:56,980 --> 00:21:02,810
+يتكلمون عن العمول اللا مرنة العيارات لا تبقى موجودة
+
+263
+00:21:02,810 --> 00:21:08,830
+وليس هناك حاجة لإدارة الحكومة لإعادة إعادة إعادة
+
+264
+00:21:08,830 --> 00:21:09,690
+إعادة إعادة إعادة إعادة إعادة إعادة إعادة إعادة
+
+265
+00:21:09,690 --> 00:21:13,810
+إعادة إعادة إعادة إعادة إعادة إعادة
+
+266
+00:21:13,810 --> 00:21:14,410
+إعادة إعادة إعادة إعادة إعادة إعادة إعادة إعادة
+
+267
+00:21:14,410 --> 00:21:14,450
+إعادة إعادة إعادة إعادة إعادة إعادة إعادة إعادة
+
+268
+00:21:14,450 --> 00:21:14,970
+إعادة إعادة إعادة إعادة إعادة إعادة إعادة إعادة
+
+269
+00:21:14,970 --> 00:21:24,650
+إعادة إعادة إعادة إعادة إعادة إعادة
+
+270
+00:21:24,650 --> 00:21:28,050
+إعادة
+
+271
+00:21:28,080 --> 00:21:34,780
+سيكون المشكلة ملحوظة بشكل مباشر بدون تقديم، بمعنى
+
+272
+00:21:34,780 --> 00:21:39,000
+العمالة إذا كانت العمالة أو عمليات المطالبة
+
+273
+00:21:39,000 --> 00:21:45,300
+تتخلص العمالة ستتخلص أيضًا، صحيح؟ لذلك لدينا ..
+
+274
+00:21:45,300 --> 00:21:49,000
+وهم يعتمدون على أن السوق دائمًا واضح أو أن السوق
+
+275
+00:21:49,000 --> 00:21:55,880
+دائمًا في أو في اتزان، صحيح؟ حسنًا ، لذلك
+
+276
+00:21:55,880 --> 00:21:57,360
+كما ترى في هذه التعليقات
+
+277
+00:22:00,920 --> 00:22:05,360
+الإزالة من قيمة الإنتاج كما ترى في هذه التحليل
+
+278
+00:22:05,360 --> 00:22:12,720
+إزالة قيمة الإنتاج يؤدي إلى تقليل السلوك الذي
+
+279
+00:22:12,720 --> 00:22:17,700
+يؤدي إلى إزالة عملية الإنتاج بطريقة مباشرة ومن ثم
+
+280
+00:22:17,700 --> 00:22:23,200
+قيمة الإنتاج ستتخلص، أليس كذلك؟ وفي مدينة العظيمة 
+
+281
+00:22:23,200 --> 00:22:30,860
+كما ترى هذه النظرية اتخذت لتشرح هذه الحالة التي 
+
+282
+00:22:30,860 --> 00:22:37,900
+تجعلها نظرية الاقتصاد الكلاسيكي، لذلك حتى عام عام
+
+283
+00:22:37,900 --> 00:22:43,640
+1929، استخدم الاقتصاد الكلاسيكي نظريات الاقتصاد 
+
+284
+00:22:43,640 --> 00:22:49,260
+الكلاسيكي على نظرية الاقتصاد الكلاسيكي أو نظرية
+
+285
+00:22:49,260 --> 00:22:50,620
+الاقتصاد الكلاسيكي
+
+286
+00:22:55,700 --> 00:23:09,020
+اللي هنشوف شو اللي صار بعد هيك according 
+287
+00:23:09,020 --> 00:23:12,840
+to the classical view as you see here we're
+288
+00:23:12,840 --> 00:23:17,520
+talking about the goods and services market they
+289
+00:23:17,520 --> 00:23:21,120
+assume that this is the aggregate supply and the
+290
+00:23:21,120 --> 00:23:27,090
+aggregate supply هي خط عرض الكلي وهذا هو الإنتاج
+291
+00:23:27,090 --> 00:23:34,390
+الإنتاج للأسعار وهذا هو مستوى الأسعار المتسوى 
+292
+00:23:34,390 --> 00:23:38,170
+أو المتسوى للأسعار والتوازن في السوق
+293
+00:23:38,170 --> 00:23:43,650
+الأسعار والمتسوى يحدث عندما يكون هناك إنتاج بين
+294
+00:23:43,650 --> 00:23:46,250
+إنتاج التّجارة والإنتاج المتسوى للأسعار إنتاج
+295
+00:23:46,250 --> 00:23:51,150
+التّجارة والإنتاج المتسوى للأسعار والإنتاج
+296
+00:23:51,150 --> 00:23:54,370
+المتسوى للأسعار والإنتاج المتسوى للأسعار إذا كان
+297
+00:23:54,370 --> 00:23:58,630
+هناك كمية عرض تتغير أو تزيد في الموارد، هذا يعيد
+298
+00:23:58,630 --> 00:24:08,050
+إلى ماذا؟ تقليل الأسعار، هم يعتقدون أن أي زيادة في
+299
+00:24:08,050 --> 00:24:15,500
+الموارد أو المصادر هناك تغيير كلمة صحيحة لتغيير
+300
+00:24:15,500 --> 00:24:18,680
+مجموعات الموارد من مجموعات الموارد 1 إلى مجموعات
+301
+00:24:18,680 --> 00:24:23,460
+الموارد 2 هذا يؤدي إلى نقطة توازن جديدة من
+302
+00:24:23,460 --> 00:24:26,740
+أولى أولى أولى أولى أولى أولى أولى أولى أولى أولى 
+303
+00:24:26,740 --> 00:24:29,440
+أولى أولى أولى أولى أولى أولى أولى أولى أولى أولى
+304
+00:24:30,960 --> 00:24:36,380
+لذلك في هذه الحالة لدينا أقل في الأسعار من P1 إلى
+305
+00:24:36,380 --> 00:24:41,260
+P2 كما ترى في الـ New  نحن لدينا نقطة توازن جديدة
+306
+00:24:41,260 --> 00:24:47,420
+من A1 إلى A2 بسبب زيادة المجموعات في المجموعات
+307
+00:24:47,420 --> 00:24:55,200
+الصحيح؟ نعم، نعم، نعم، بالضبط، ولكن في هذه الحالة،
+308
+00:24:55,200 --> 00:24:59,540
+الآن أعتقد أن الأسعار 
+309
+00:24:59,540 --> 00:25:04,510
+مرتبطة الأسعار جامدة و ظلت الأسعار جامدة in this
+310
+00:25:04,510 --> 00:25:11,130
+case the aggregate supply is larger than the
+311
+00:25:11,130 --> 00:25:16,530
+aggregate demand right according to the classical
+312
+00:25:16,530 --> 00:25:19,090
+view assumption or the classical economist
+313
+00:25:19,090 --> 00:25:25,770
+assumption إذا كان السعر مستمر في P1 في مجتمع
+314
+00:25:25,770 --> 00:25:29,790
+الأسعار في هذه الحالة ، هذا كميات من عرض الكلي
+315
+00:25:29,790 --> 00:25:35,330
+، لذلك يظهر كميات من عرض الكلي وهذا كميات من
+316
+00:25:35,330 --> 00:25:38,310
+عرض الكلي ، لذلك هذا كميات من عرض الكلي ،
+317
+00:25:38,310 --> 00:25:42,230
+لذلك في هذه الحالة كميات العرض المكتوبة أكثر من
+318
+00:25:42,230 --> 00:25:43,690
+الكمية المطلوبة ، نعم
+319
+00:25:50,940 --> 00:26:00,440
+الاستيك يعني مرتبط ليس مرتبط، نعم لأ ما قلتش ما
+320
+00:26:00,440 --> 00:26:05,480
+يحتاج ..
+321
+00:26:05,480 --> 00:26:12,520
+لأ لأ I said that suppose that the price is sticky
+322
+00:26:15,010 --> 00:26:18,690
+حسنًا، حسنًا، كانوا يعتمدوا إذا كان السعر مستمر أو
+323
+00:26:18,690 --> 00:26:23,170
+مستمر مستمر، ماذا سيحدث؟ سعر العرض هو أكثر من
+324
+00:26:23,170 --> 00:26:27,850
+السعر المطلوب، صحيح؟ هذا يعني ماذا؟ أقل السعر
+325
+00:26:27,850 --> 00:26:31,550
+لدينا نقطة توازن جديدة، لذلك هم ما افترضوا أن 
+326
+00:26:31,550 --> 00:26:35,210
+السعر مستقل، هم قالوا لك لو أنه أجي حد ناقشنا وقالك
+327
+00:26:35,210 --> 00:26:39,170
+أنه خلي الأسعار، الأسعار بتظل جامدة، بقولك هم، هم
+328
+00:26:39,170 --> 00:26:42,550
+قالوا أن الأسعار ما بتكونش جامدة، the same idea
+329
+00:26:42,550 --> 00:26:50,580
+for the wages الأجور مرتبطة أو مرتبطة صحيح؟ حسنا،
+330
+00:26:50,580 --> 00:26:56,740
+هل هذا صحيح؟ لأ لأ لأ لأ هي الوضع هيك أنه لو أحد 
+331
+00:26:56,740 --> 00:27:00,340
+ناقشهم بيقولوا أن لو أحد ناقشنا وقالك أن الأجور
+332
+00:27:00,340 --> 00:27:05,080
+بتبقى ثابتة لأ طبعًا بيقولوا أنها مرتبطة مرتبطة
+333
+00:27:05,080 --> 00:27:08,900
+صحيح؟ لذلك في هذه الحالة الأجور المطلوبة هي أكثر 
+334
+00:27:08,900 --> 00:27:12,180
+من الأجور المطلوبة كما ترى عندما يكون الأجور 
+335
+00:27:12,180 --> 00:27:17,820
+المطلوبة هي أكثر من ما تتطلبه الكمية هناك موارد
+336
+00:27:17,820 --> 00:27:21,740
+تسلسلية من الأسعار تسلسلية إلى ماذا؟ تسلسلية إلى 
+337
+00:27:21,740 --> 00:27:27,920
+تقليل الأسعار فإن تقليل الأسعار هو تقليل الأسعار
+338
+00:27:27,920 --> 00:27:35,580
+بشكل مباشر بدون تقليل من أي حكومة أو أي شركة أخرى،
+339
+00:27:35,580 --> 00:27:41,860
+صحيح؟ لذلك، باعتبار تقليل الأسعار ليس مرتبطًا
+340
+00:27:48,770 --> 00:27:55,830
+نعم ، نعم ، لذلك هذا يؤدي إلى تقسيم الأسعار أشياء
+341
+00:27:55,830 --> 00:28:00,930
+أخرى مرتبطة بالتحقيق الكلاسيكي إنهم يعتمدوا على أن
+342
+00:28:00,930 --> 00:28:09,250
+إذا أسعارها تتخلص ، فسيتخلص السلوك وإذا أسعارها
+343
+00:28:09,250 --> 00:28:15,670
+أكثر ، فسيكتر السلوك لأن إذا أسعارها أكثر
+344
+00:28:21,390 --> 00:28:31,190
+العملاء سيطلبوا لعملائهم أن يقدموا لهم عمليات
+345
+00:28:31,190 --> 00:28:32,470
+إضافية إضافية إضافية إضافية إضافية إضافية إضافية
+346
+00:28:32,470 --> 00:28:36,570
+إضافية إضافية إضافية إضافية إضافية إضافية إضافية
+347
+00:28:36,570 --> 00:28:40,030
+إضافية إضافية إضافية إضافية إضافية إضافية إضافية
+348
+00:28:40,030 --> 00:28:41,070
+إضافية إضافية إضافية إضافية إضافية إضافية إضافية
+349
+00:28:41,070 --> 00:28:41,090
+إضافية إضافية إضافية إضافية إضافية إضافية إضافية
+350
+00:28:41,090 --> 00:28:44,590
+إضافية إضافية إضافية إضافية إضافية إضافية إضافية
+351
+00:28:44,590 --> 00:28:46,650
+إضاف
+352
+00:28:49,080 --> 00:28:56,060
+لنذهب إلى مشكلة أخرى، كما ذكرت أن النظر الكلاسيكي
+353
+00:28:56,060 --> 00:29:03,040
+يعتمد أن الموارد تخلق طلب، تخلق طلب، هذا يعني أن
+354
+00:29:03,040 --> 00:29:04,380
+إذا كانت الموارد تخلق
+355
+00:29:07,540 --> 00:29:14,720
+كل هذه الأشياء ستتسلل وهذا يسبب في إصلاح الحصول
+356
+00:29:14,720 --> 00:29:22,920
+على موارد مستخدمين يستطيعون شراء مجموعات مختلفة أو
+357
+00:29:22,920 --> 00:29:27,380
+شراء مجموعات مختلفة من الأشياء والخدمات فإنهم 
+358
+00:29:27,380 --> 00:29:34,700
+يعتمدوا إذا 
+359
+00:29:34,700 --> 00:29:35,820
+كان لدينا إخراجات
+360
+00:29:38,810 --> 00:29:43,110
+استخدام الاستخدام الاستخدام يعني استخدام الاستخدام
+361
+00:29:43,110 --> 00:29:46,150
+استخدام استخدام استخدام استخدام استخدام استخدام
+362
+00:29:46,150 --> 00:29:48,370
+استخدام استخدام استخدام استخدام استخدام استخدام
+363
+00:29:48,370 --> 00:29:48,790
+استخدام استخدام استخدام استخدام استخدام استخدام
+364
+00:29:48,790 --> 00:29:49,870
+استخدام استخدام استخدام استخدام استخدام استخدام
+365
+00:29:49,870 --> 00:29:49,930
+استخدام استخدام استخدام استخدام استخدام استخدام
+366
+00:29:49,930 --> 00:29:49,990
+استخدام استخدام استخدام استخدام استخدام استخدام
+367
+00:29:49,990 --> 00:29:56,790
+استخدام استخدام استخدام استخدام استخدام استخدام
+368
+00:29:56,790 --> 00:30:01,790
+استخدام
+369
+00:30:07,250 --> 00:30:08,610
+للعاملين العاملين العاملين العاملين العاملين
+370
+00:30:08,610 --> 00:30:10,150
+العاملين العاملين العاملين العاملين العاملين
+371
+00:30:10,150 --> 00:30:11,490
+العاملين العاملين العاملين العاملين العاملين
+372
+00:30:11,490 --> 00:30:12,790
+العاملين العاملين العاملين العاملين العاملين
+373
+00:30:12,790 --> 00:30:14,210
+العاملين العاملين العاملين العاملين العاملين
+374
+00:30:14,210 --> 00:30:15,470
+العاملين العاملين العاملين العاملين العاملين
+375
+00:30:15,470 --> 00:30:17,750
+العاملين العاملين العاملين العاملين العاملين
+376
+00:30:17,750 --> 00:30:18,130
+العاملين العاملين العاملين العاملين العاملين
+377
+00:30:18,130 --> 00:30:18,170
+العاملين العاملين العاملين العاملين العاملين
+378
+00:30:18,170 --> 00:30:20,530
+العاملين العاملين العاملين العاملين العاملين
+379
+00:30:20,530 --> 00:30:32,670
+العاملين العاملين العاملين العاملين العاملين العام
+380
+00:30:39,980 --> 00:30:45,140
+Okay during the great depression unfortunately
+381
+00:30:45,140 --> 00:30:53,180
+there was large quantities of outputs and no one
+382
+00:30:53,180 --> 00:30:59,880
+bought it which called recession or deep recession
+383
+00:30:59,880 --> 00:31:06,260
+اللي هو depression في بضاعة كثير وماحدش راضي ..
+384
+00:31:06,260 --> 00:31:10,790
+ماحدش قادر يشتريهم according to the classical view
+385
+00:31:10,790 --> 00:31:17,530
+they assume that if we have large outputs all of
+386
+00:31:17,530 --> 00:31:21,130
+these outputs would be purchased because
+387
+00:31:21,130 --> 00:31:24,810
+increasing the outputs leads to a reduction in the
+388
+00:31:24,810 --> 00:31:29,270
+prices هم إيش قالوا؟ إنه increasing the outputs
+389
+00:31:29,270 --> 00:31:37,630
+leads to a reduction in the prices تقليل السعر يؤدي
+390
+00:31:37,630 --> 00:31:44,870
+إلى زيادة القوة الشرائية للمستخدمين تقليل القهوة
+391
+00:31:44,870 --> 00:31:50,370
+الشرائية للمستخدمين تقليل القوة الشرائية
+392
+00:31:50,370 --> 00:31:53,910
+القوة الشرائية للمستخدمين تقليل
+393
+00:31:53,910 --> 00:31:56,370
+القوة الشرائية للمستخدمين تقليل القوة الشرائية
+394
+00:31:56,370 --> 00:31:57,070
+للمستخدمين تقليل القوة الشرائية للمستخدمين تقليل
+395
+00:31:57,070 --> 00:31:57,150
+القوة الشرائية للمستخدمين تقليل القوة الشرائية
+396
+00:31:57,150 --> 00:32:02,390
+للمستخدمين تقليل القوة الشرائية للمستخدمين تقليل
+397
+00:32:02,390 --> 00:32:08,540
+القوة الشرائية للمستخدمين إخراجات أو إخراجات كبيرة و
+398
+00:32:08,540 --> 00:32:17,460
+هذه الإخراجات لم تتسوق
+399
+00:32:17,460 --> 00:32:22,820
+أو تسوق لأن
+400
+00:32:22,820 --> 00:32:29,560
+المستخدمين لم يكن لديهم القدرة أو القدرة أن يشتري
+401
+00:32:29,560 --> 00:32:37,420
+هذه الأجهزة لماذا نصل لهذه النقطة؟ لأ .. لأ .. لأ
+402
+00:32:37,420 --> 00:32:41,980
+.. في ذلك الوقت .. في تلك التحركات .. السعر يتخلص 
+403
+00:32:41,980 --> 00:32:47,900
+.. لدينا عدد عمليات عالي .. لدينا إخراجات عالية ..
+404
+00:32:47,900 --> 00:32:55,880
+و جميع هذه الإخراجات تم تخزينها .. تمام؟ فخلينا
+405
+00:32:55,880 --> 00:33:01,140
+نشوف ما هي الأسباب الرئيسية للتحريك الكبير .. و
+406
+00:33:01,140 --> 00:33:04,480
+الـ prolonged أو الـ deep recession
+407
+00:33:06,710 --> 00:33:11,150
+الثلاثينات العظيمة الثلاثينات العظيمة هي أو كانت
+408
+00:33:11,150 --> 00:33:18,210
+مرحلة من اتفاق اقتصاد عالي وإنتاج عالي اللي بدأت
+409
+00:33:18,210 --> 00:33:26,910
+في عام 1929 وكمان في عام 33 عام استمرت لفترة
+410
+00:33:26,910 --> 00:33:33,870
+الثلاثينات كمان التحديات الكبيرة بدأت بانهيار بورصة
+411
+00:33:33,870 --> 00:33:40,390
+السوق بسبب
+412
+00:33:40,390 --> 00:33:47,150
+انهيار بورصة السوق بسبب انهيار بورصة السوق بسبب
+413
+00:33:47,150 --> 00:33:49,470
+انهيار بورصة السوق بسبب انهيار بورصة السوق بسبب
+414
+00:33:49,470 --> 00:33:55,750
+انهيار بورصة السوق بسبب انهيار كان هناك تقليل أو
+415
+00:33:55,750 --> 00:33:59,150
+تقليل الوصول الحقيقي لأننا لدينا تقليل تقليل
+416
+00:33:59,150 --> 00:34:06,050
+الاستثمارات، صحيح؟ لذلك، تقليل الشركات أو تقليل تقليل
+417
+00:34:06,050 --> 00:34:06,830
+تقليل تقليل تقليل تقليل تقليل تقليل تقليل تقليل
+418
+00:34:06,830 --> 00:34:11,810
+تقليل تقليل تقليل تقليل تقليل تقليل تقليل تقليل
+419
+00:34:11,810 --> 00:34:11,950
+تقليل تقليل تقليل تقليل تقليل تقليل تقليل تقليل
+420
+00:34:11,950 --> 00:34:21,790
+تقليل تقليل تقليل تقليل تقليل تقليل تقليل تقليل 
+
+421
+00:34:23,590 --> 00:34:32,210
+و كما ترى هنا نحن لدينا قيمة غير مجتمعة عالية هذا
+
+422
+00:34:32,210 --> 00:34:39,250
+صورة مرتبطة بمحطة السوق نعم
+
+423
+00:34:39,250 --> 00:34:49,850
+لذلك في عام 1929 كثير من الأمريكيين كانوا مستثمرين
+
+424
+00:34:49,850 --> 00:34:54,490
+في محطة السوق في الـ .. في الـ 1929 كل الناس صارت
+
+425
+00:34:54,490 --> 00:35:00,970
+تشتري stocks of bonds أسهم و سندات and they
+
+426
+00:35:00,970 --> 00:35:05,970
+invested heavily in the stock market طيب the banks
+
+427
+00:35:05,970 --> 00:35:10,010
+or the stock market had become the most visible
+
+428
+00:35:10,010 --> 00:35:13,850
+sector for investment so all the Americans
+
+429
+00:35:13,850 --> 00:35:17,150
+invested heavily in the stock market هذا في الـ 1929
+
+430
+00:35:17,150 --> 00:35:25,680
+then لذلك كما ترى جميعهم ذهبوا لـ Stock Market
+
+431
+00:35:25,680 --> 00:35:29,820
+لتشرح شركاتهم لتشرح شركاتهم لتشرح شركاتهم لتشرح 
+
+432
+00:35:29,820 --> 00:35:33,000
+شركاتهم لتشرح شركاتهم لتشرح شركاتهم لتشرح شركاتهم
+
+433
+00:35:33,000 --> 00:35:33,700
+لتشرح شركاتهم لتشرح شركاتهم لتشرح شركاتهم لتشرح 
+
+434
+00:35:33,700 --> 00:35:33,960
+لتشرح شركاتهم لتشرح شركاتهم لتشرح شركاتهم لتشرح 
+
+435
+00:35:33,960 --> 00:35:35,340
+شركاتهم لتشرح شركاتهم لتشرح شركاتهم لتشرح شركاتهم
+
+436
+00:35:35,340 --> 00:35:40,660
+لتشرح شركاتهم لتشرح شركاتهم
+
+437
+00:35:40,660 --> 00:35:45,220
+لتشرح شركاتهم لتشرح شركاتهم لتشرح 
+
+438
+00:35:56,130 --> 00:35:59,190
+والسعر المضارب يزال يزال يزال يزال يزال يزال يزال
+
+439
+00:35:59,190 --> 00:35:59,390
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+440
+00:35:59,390 --> 00:35:59,730
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+441
+00:35:59,730 --> 00:36:03,110
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+442
+00:36:03,110 --> 00:36:04,150
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+443
+00:36:04,150 --> 00:36:14,490
+يزال يزال يزال يزال يز
+
+444
+00:36:15,730 --> 00:36:19,290
+حاولت أن تحصل على أرباح كبيرة لذلك استثموا
+
+445
+00:36:19,290 --> 00:36:23,210
+كثيرًا في السوق اتفاقات كبيرة على السوق والجسيم
+
+446
+00:36:23,210 --> 00:36:29,030
+قبل 1929 قبل الفترة هذه كل كان بيشتري جسيم و
+
+447
+00:36:29,030 --> 00:36:35,250
+بيشتري السوق لذلك كما ترى هذا البرنامج أو هذه
+
+448
+00:36:35,250 --> 00:36:40,410
+الصورة تظهر اتفاقات 
+
+449
+00:36:40,410 --> 00:36:40,990
+السوق
+
+450
+00:36:43,530 --> 00:36:54,370
+الذي يظهر زي ذلك أن زي دي دي دي دي دي دي دي دي دي
+
+451
+00:36:54,370 --> 00:36:54,430
+دي دي دي دي دي دي دي دي دي دي دي دي دي دي دي دي
+
+452
+00:36:54,430 --> 00:36:54,490
+دي دي دي دي دي دي دي دي دي دي دي دي دي دي دي دي
+
+453
+00:36:54,490 --> 00:36:54,510
+دي دي دي دي دي دي دي دي دي دي دي دي دي دي دي دي
+
+454
+00:37:13,520 --> 00:37:17,700
+صار في انخفاض في أسعار الـ stocks بدأ اللي اللي
+
+455
+00:37:17,700 --> 00:37:22,550
+اللي اللي اللي المستثمر أصلا في الـ stocks بدأ يواجه
+
+456
+00:37:22,550 --> 00:37:26,050
+مشاكل في طالما أنه فيه reduction في الـ prices of
+
+457
+00:37:26,050 --> 00:37:31,690
+stocks صرف دول مية كمان الـ banks .. banks invested
+
+458
+00:37:31,690 --> 00:37:34,510
+heavily in the stocks in that period so they try
+
+459
+00:37:34,510 --> 00:37:38,670
+.. so as you see high percentage of Americans sold
+
+460
+00:37:38,670 --> 00:37:42,650
+their bonds and stocks كله صار بيها، so supply for
+
+461
+00:37:42,650 --> 00:37:48,300
+stocks و decline أو أسف إضافة .. إضافة .. إضافة في
+
+462
+00:37:48,300 --> 00:37:50,740
+هذا الوقت لأسعار الأسعار .. إضافة في هذا الوقت
+
+463
+00:37:50,740 --> 00:37:51,960
+لأسعار الأسعار .. إضافة في هذا الوقت لأسعار
+
+464
+00:37:51,960 --> 00:37:52,000
+الأسعار .. إضافة في هذا الوقت لأسعار الأسعار ..
+
+465
+00:37:52,000 --> 00:37:53,300
+إضافة في هذا الوقت لأسعار الأسعار .. إضافة في هذا
+
+466
+00:37:53,300 --> 00:37:53,480
+الوقت لأسعار الأسعار .. إضافة في هذا الوقت لأسعار
+
+467
+00:37:53,480 --> 00:37:53,920
+الأسعار .. إضافة في هذا الوقت لأسعار الأسعار ..
+
+468
+00:37:53,920 --> 00:38:02,420
+إضافة في هذا الوقت لأسعار الأسعار .. إضافة
+
+469
+00:38:02,420 --> 00:38:06,440
+في هذا الوقت لأسعار الأسعار .. إضافة في هذا الوقت
+
+470
+00:38:06,440 --> 00:38:12,020
+لأسعار
+
+471
+00:38:12,020 --> 00:38:19,300
+الأسعار ..نعم، كما ترى هذا البرنامج يظهر زيادة
+
+472
+00:38:19,300 --> 00:38:23,240
+في أسعار
+
+473
+00:38:23,240 --> 00:38:28,620
+الأسعار من S1 إلى S2، فهذا يؤدي إلى تقليل أسعار
+
+474
+00:38:28,620 --> 00:38:38,340
+الأسعار في ذلك الوقت في عام 1929 أكثر 
+
+475
+00:38:38,340 --> 00:38:41,560
+الناس لم يكن لديها مال لشراء
+
+476
+00:38:46,900 --> 00:38:51,040
+والوحد كان قادر يشتري لبضائع اللي بتنتجها المصانع
+
+477
+00:38:51,040 --> 00:38:55,620
+لأنه خلصنا So the factories and business collapsed
+
+478
+00:38:55,620 --> 00:38:59,720
+and closed طيب
+
+479
+00:38:59,720 --> 00:39:05,700
+unemployment rate increased for sure and according
+
+480
+00:39:05,700 --> 00:39:09,900
+to the classical view they assume that if we have
+
+481
+00:39:11,850 --> 00:39:14,490
+على إزالة الإنترنت المجاورة ستزال التطبيق التجاري
+
+482
+00:39:14,490 --> 00:39:17,170
+يتزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+483
+00:39:17,170 --> 00:39:17,770
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+484
+00:39:17,770 --> 00:39:24,630
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+485
+00:39:24,630 --> 00:39:25,190
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+486
+00:39:25,190 --> 00:39:25,550
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+487
+00:39:25,550 --> 00:39:25,570
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+488
+00:39:25,570 --> 00:39:38,070
+تزال تزال تزال تزال تزال 
+
+489
+00:39:38,070 --> 00:39:41,650
+ت
+
+490
+00:39:42,140 --> 00:39:46,680
+مش بس الناس اللي استثمروا في الـ stocks في الفترة
+
+491
+00:39:46,680 --> 00:39:52,740
+دي الـ banks كمان مش بس الناس اللي استثمروا في الـ
+
+492
+00:39:52,740 --> 00:39:54,860
+stocks في الفترة دي الـ banks كمان مش بس الناس
+
+493
+00:39:54,860 --> 00:39:58,200
+اللي استثمروا في الـ stocks في الفترة دي الـ banks
+
+494
+00:39:58,200 --> 00:40:01,880
+كمان مش بس الناس اللي استثمروا في الـ stocks في
+
+495
+00:40:01,880 --> 00:40:04,360
+الفترة دي الـ banks كمان مش بس الناس اللي استثمروا
+
+496
+00:40:04,360 --> 00:40:07,220
+في الـ stocks في الفترة دي الـ banks لذلك كانت
+
+497
+00:40:07,220 --> 00:40:11,740
+الشركات كانت تستثمر كثيرًا في السوق وفقدت المال،
+
+498
+00:40:11,740 --> 00:40:16,160
+وكانت الشركات تسقط أيضًا أو تسقط أيضًا أيضًا.
+
+499
+00:40:17,900 --> 00:40:25,670
+الآن، باعتبار النظر الكلاسيكي أو النظر الكينيزي لدينا
+
+500
+00:40:25,670 --> 00:40:29,330
+نتيجة عالية أو نتيجة أكثر من نتيجة أكثر من نتيجة
+
+501
+00:40:29,330 --> 00:40:30,650
+أكثر من نتيجة أكثر من نتيجة أكثر من نتيجة أكثر من 
+
+502
+00:40:30,650 --> 00:40:34,830
+نتيجة أكثر من نتيجة أكثر من نتيجة أكثر من نتيجة
+
+503
+00:40:34,830 --> 00:40:36,830
+أكثر من نتيجة أكثر من نتيجة أكثر من نتيجة أكثر من 
+
+504
+00:40:36,830 --> 00:40:36,870
+نتيجة أكثر من نتيجة أكثر من نتيجة أكثر من نتيجة
+
+505
+00:40:36,870 --> 00:40:37,910
+أكثر من نتيجة أكثر من نتيجة أكثر من نتيجة أكثر من 
+
+506
+00:40:37,910 --> 00:40:52,030
+نتيجة أكثر من نتيجة أكثر من نتيجة أكثر من نتيجة
+
+507
+00:40:52,030 --> 00:40:58,890
+أنه الحكومة يجب أن تقوم بإعادة لتحل المشكلة، لدينا
+
+508
+00:40:58,890 --> 00:41:02,010
+عدد عاطلين كبير، لدينا عدد عاطلين كبير، لدينا عدد عاطلين
+
+509
+00:41:02,010 --> 00:41:03,070
+كبير، لدينا عدد عاطلين كبير، لدينا عدد عاطلين كبير،
+
+510
+00:41:03,070 --> 00:41:04,170
+لدينا عدد عاطلين كبير، لدينا عدد عاطلين كبير، لدينا
+
+511
+00:41:04,170 --> 00:41:05,670
+كبير، لدينا عدد عاطلين كبير، لدينا عدد عاطلين كبير،
+
+512
+00:41:05,670 --> 00:41:10,010
+لدينا عدد عاطلين كبير، لدينا عدد عاطلين كبير، لدينا
+
+513
+00:41:10,010 --> 00:41:20,440
+عدد عاطلين كبير، لدينا قام باقتصاد أن الحكومة يجب أن
+
+514
+00:41:20,440 --> 00:41:24,600
+تشجع الطلب 
+
+515
+00:41:24,600 --> 00:41:31,740
+المجتمع لذلك
+
+516
+00:41:31,740 --> 00:41:34,240
+يجب أن تستخدم الحكومة استخدام استخدام استخدام 
+
+517
+00:41:34,240 --> 00:41:38,710
+استخدام استخدام استخدام سياسة مالية توسعية by
+
+518
+00:41:38,710 --> 00:41:43,210
+increasing expenditure on to buy different
+
+519
+00:41:43,210 --> 00:41:46,810
+products and goods and services. So according to
+
+520
+00:41:46,810 --> 00:41:49,730
+the Keynesian theory, the level of employment is
+
+521
+00:41:49,730 --> 00:41:52,150
+not determined by the wages and prices, but
+
+522
+00:41:52,150 --> 00:41:55,670
+determined by the aggregate demand for goods and
+
+523
+00:41:55,670 --> 00:41:59,030
+services. بالـ classical شو قالوا؟ قالوا أن الـ wages
+
+524
+00:41:59,030 --> 00:42:05,730
+and the prices هو ليس صحيح أو ليس صحيح، فهو مستقل 
+
+525
+00:42:05,730 --> 00:42:10,670
+لتحل الانتاج، ولكن باعتبار الـ Keynesian view،
+
+526
+00:42:10,670 --> 00:42:17,110
+ليس كذلك، لذلك يجب أن تعمل الحكومة تسجيل أموال
+
+527
+00:42:17,110 --> 00:42:21,670
+المجتمع باستخدام نظام اتفاق اتفاق، يعطيكم العافية
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/HM3y5vmjj20_raw.json b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/HM3y5vmjj20_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..7e2815b11eb53cc0dc619f66fc938433d3a64428
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/HM3y5vmjj20_raw.json
@@ -0,0 +1 @@
+{"segments": [{"id": 1, "seek": 4733, "start": 20.65, "end": 47.33, "text": "بسم الله الرحمن الرحيم اليوم إن شاء الله سنكمل الحلقة الرابعة ونبدأ في الحلقة الخامسة الأخيرة في الحلقة الرابعة وهي المضاعف المضاعف يعني المضاعف لتفهم فكرة المضاعف دعونا نأخذ مثلًا مثلًا لتفهم مصطلح المضاعف صح؟", "tokens": [3555, 38251, 21984, 34892, 5016, 27842, 34892, 5016, 32640, 45595, 20498, 36145, 13412, 16606, 21984, 8608, 1863, 24793, 1211, 21542, 1211, 28671, 34892, 16758, 27884, 4032, 1863, 44510, 10721, 8978, 21542, 1211, 28671, 33962, 10943, 3794, 3660, 16247, 9778, 48923, 8978, 21542, 1211, 28671, 34892, 16758, 27884, 37037, 1829, 9673, 11242, 45761, 5172, 9673, 11242, 45761, 5172, 37495, 22653, 9673, 11242, 45761, 5172, 5296, 2655, 5172, 16095, 6156, 4117, 25720, 9673, 11242, 45761, 5172, 11778, 3615, 2407, 8315, 8717, 10721, 9778, 8848, 50113, 1211, 14111, 995, 50113, 1211, 14111, 995, 5296, 2655, 5172, 16095, 3714, 9381, 9566, 1211, 5016, 9673, 11242, 45761, 5172, 20328, 5016, 22807], 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"temperature": 1.0}, {"id": 22, "seek": 62245, "start": 594.67, "end": 622.45, "text": "هذا يعني تغيير البرمجة في الـ Y بسبب تغيير الانتجار المخطط في هذه الحالة تمام؟ يعني سببز أن الانتجار أزداد من 100 مليون دولار كم هو التغيير في الوصول الانتجاري؟ هذا هو المصطلح من مستخدم الانتجار المختلف، صحيح؟ وهو يقل 1 على 1 مانوس MBC", "tokens": [3224, 15730, 37495, 22653, 6055, 17082, 1829, 13546, 2423, 26890, 2304, 7435, 3660, 8978, 2423, 39184, 398, 4724, 35457, 3555, 6055, 17082, 1829, 13546, 2423, 7649, 2655, 7435, 9640, 9673, 9778, 9566, 9566, 8978, 29538, 21542, 6027, 3660, 6055, 15042, 2304, 22807, 37495, 22653, 8608, 3555, 3555, 11622, 14739, 2423, 7649, 2655, 7435, 9640, 5551, 11622, 3215, 18513, 9154, 2319, 3714, 20292, 11536, 11778, 12610, 9640, 9122, 2304, 31439, 16712, 17082, 1829, 13546, 8978, 2423, 2407, 9381, 12610, 2423, 7649, 2655, 7435, 9640, 1829, 22807, 23758, 31439, 9673, 9381, 9566, 1211, 5016, 9154, 3714, 14851, 9778, 40448, 2423, 7649, 2655, 7435, 9640, 9673, 46456, 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"temperature": 1.0}, {"id": 24, "seek": 67732, "start": 651.86, "end": 677.32, "text": "فاعتبار أن الحكومة أو المجتمع قرر ان يستخدم أو يزيد مستخدمها من 100 مليون دولار فاعتبار I من 100 مليون دولار يقل لـ Delta I يقل لـ 100 مليون دولار فاعتبار MBC", "tokens": [5172, 995, 34268, 3555, 9640, 14739, 21542, 4117, 20498, 3660, 34051, 9673, 7435, 39237, 3615, 12174, 2288, 2288, 16472, 7251, 14851, 9778, 40448, 34051, 7251, 11622, 25708, 3714, 14851, 9778, 40448, 11296, 9154, 2319, 3714, 20292, 11536, 11778, 12610, 9640, 6156, 995, 34268, 3555, 9640, 286, 9154, 2319, 3714, 20292, 11536, 11778, 12610, 9640, 7251, 4587, 1211, 5296, 39184, 18183, 286, 7251, 4587, 1211, 5296, 39184, 2319, 3714, 20292, 11536, 11778, 12610, 9640, 6156, 995, 34268, 3555, 9640, 376, 7869], "avg_logprob": -0.5972222339959792, "compression_ratio": 1.8472222222222223, "no_speech_prob": 0.0, "words": [{"start": 651.86, "end": 653.16, "word": "فاعتبار", "probability": 0.4080078125}, {"start": 653.16, "end": 654.44, "word": 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"probability": 0.9270833333333334}, {"start": 661.72, "end": 662.16, "word": " دولار", "probability": 0.9296875}, {"start": 662.16, "end": 663.42, "word": " فاعتبار", "probability": 0.66357421875}, {"start": 663.42, "end": 665.3, "word": " I", "probability": 0.62548828125}, {"start": 665.3, "end": 665.9, "word": " من", "probability": 0.787109375}, {"start": 665.9, "end": 667.18, "word": " 100", "probability": 0.87353515625}, {"start": 667.18, "end": 667.86, "word": " مليون", "probability": 0.9833984375}, {"start": 667.86, "end": 668.3, "word": " دولار", "probability": 0.9734700520833334}, {"start": 668.3, "end": 669.94, "word": " يقل", "probability": 0.23836263020833334}, {"start": 669.94, "end": 670.66, "word": " لـ", "probability": 0.3646240234375}, {"start": 670.66, "end": 671.04, "word": " Delta", "probability": 0.19580078125}, {"start": 671.04, "end": 671.46, "word": " I", "probability": 0.8955078125}, {"start": 671.46, "end": 672.1, "word": " يقل", "probability": 0.72607421875}, 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"end": 1226.43, "text": "هلأ دخلنا الزيادات هذي صارت نتيجة إيش؟ إنه فيه changes في ال MBC أو sorry it depends on the marginal propensity consumed We have the formula which is delta Y over delta I equals one over one minus MBC It's a formula So in this case calculate the change of Y", "tokens": [3224, 1211, 10721, 11778, 9778, 1211, 8315, 6024, 110, 1829, 18513, 9307, 8032, 8848, 1829, 20328, 9640, 2655, 8717, 31371, 7435, 3660, 11933, 1829, 8592, 22807, 36145, 3224, 8978, 3224, 2962, 8978, 2423, 376, 7869, 34051, 2597, 309, 5946, 322, 264, 16885, 2365, 6859, 21226, 492, 362, 264, 8513, 597, 307, 8289, 398, 670, 8289, 286, 6915, 472, 670, 472, 3175, 376, 7869, 467, 311, 257, 8513, 407, 294, 341, 1389, 8873, 264, 1319, 295, 398], "avg_logprob": -0.3068181880108722, "compression_ratio": 1.331858407079646, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 1203.29, "end": 1203.65, "word": "هلأ", "probability": 0.2974039713541667}, {"start": 1203.65, "end": 1204.19, "word": " 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{"start": 1253.16, "end": 1253.98, "word": " دولار", "probability": 0.8878580729166666}, {"start": 1253.98, "end": 1254.68, "word": " أو", "probability": 0.70947265625}, {"start": 1254.68, "end": 1255.24, "word": " تزيد", "probability": 0.3546549479166667}, {"start": 1255.24, "end": 1255.56, "word": " في", "probability": 0.70849609375}, {"start": 1255.56, "end": 1255.8, "word": " المستخدم", "probability": 0.53521728515625}, {"start": 1255.8, "end": 1255.94, "word": " المخطط", "probability": 0.515899658203125}, {"start": 1255.94, "end": 1256.94, "word": " لـ100", "probability": 0.3668009440104167}, {"start": 1256.94, "end": 1257.42, "word": " مليون", "probability": 0.9894205729166666}, {"start": 1257.42, "end": 1257.88, "word": " دولار،", "probability": 0.838623046875}, {"start": 1257.88, "end": 1258.9, "word": " فالنتيجة", "probability": 0.6575520833333334}, {"start": 1258.9, "end": 1259.26, "word": " الأخيرة", "probability": 0.8289388020833334}, {"start": 1259.26, "end": 1260.12, "word": " كانت", "probability": 0.633056640625}, {"start": 1260.12, "end": 1260.96, "word": " تزيد", "probability": 0.8445638020833334}, {"start": 1260.96, "end": 1261.3, "word": " في", "probability": 0.89013671875}, {"start": 1261.3, "end": 1261.68, "word": " الوصول", "probability": 0.44842529296875}, {"start": 1261.68, "end": 1262.34, "word": " المجتمعي", "probability": 0.460693359375}, {"start": 1262.34, "end": 1264.74, "word": " بـ333", "probability": 0.72119140625}, {"start": 1264.74, "end": 1264.86, "word": " مليون", "probability": 0.742431640625}, {"start": 1264.86, "end": 1265.38, "word": " دولار،", "probability": 0.885498046875}, {"start": 1265.38, "end": 1266.38, "word": " صحيح؟", "probability": 0.8376953125}, {"start": 1266.38, "end": 1266.86, "word": " نفس", "probability": 0.737548828125}, {"start": 1266.86, "end": 1267.28, "word": " الفكرة", "probability": 0.7469075520833334}, {"start": 1267.28, "end": 1269.54, "word": " لـGovernment", "probability": 0.541259765625}, {"start": 1269.54, "end": 1270.18, "word": " Spending", "probability": 0.880126953125}, {"start": 1270.18, "end": 1270.98, "word": " Multiplier", "probability": 0.88037109375}], "temperature": 1.0}, {"id": 48, "seek": 128070, "start": 1272.76, "end": 1280.7, "text": "هو يحتوي على نفس المصطلح ونفس المفهوم فاعتبار أن الحكومة قررت ان تزيد عقدتها", "tokens": [3224, 2407, 7251, 33753, 45865, 15844, 8717, 36178, 9673, 9381, 9566, 1211, 5016, 4032, 1863, 36178, 9673, 5172, 3224, 20498, 6156, 995, 34268, 3555, 9640, 14739, 21542, 4117, 20498, 3660, 12174, 2288, 2288, 2655, 16472, 6055, 11622, 25708, 6225, 28543, 2655, 11296], "avg_logprob": -0.6780523006306138, "compression_ratio": 1.3365384615384615, "no_speech_prob": 0.0, "words": [{"start": 1272.76, "end": 1273.06, "word": "هو", "probability": 0.41387939453125}, {"start": 1273.06, "end": 1273.28, "word": " يحتوي", "probability": 0.3368326822916667}, {"start": 1273.28, "end": 1273.5, "word": " على", "probability": 0.86572265625}, {"start": 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"text": "ليس المجتمع العملي، ولكن الحكومة قررت إزالة تدفعها. كما تعلمين، تدفع الحكومة أو إزالة تدفع الحكومة يؤدي إلى إزالة الـ aggregate output، صحيح؟ لذلك، لديها نفس الأفعال. سواء كان الحكومة قررت إزالة تدفعها أو إزالة تدفع الحكومة G بـ 100 مليون دولار.", "tokens": [20292, 3794, 9673, 7435, 39237, 3615, 18863, 42213, 1829, 12399, 35525, 19452, 21542, 4117, 20498, 3660, 12174, 2288, 2288, 2655, 11933, 11622, 6027, 3660, 6055, 3215, 5172, 3615, 11296, 13, 9122, 15042, 37279, 19528, 9957, 12399, 6055, 3215, 5172, 3615, 21542, 4117, 20498, 3660, 34051, 11933, 11622, 6027, 3660, 6055, 3215, 5172, 3615, 21542, 4117, 20498, 3660, 7251, 33604, 16254, 30731, 11933, 11622, 6027, 3660, 2423, 39184, 26118, 5598, 12399, 20328, 5016, 1829, 5016, 22807, 5296, 8848, 23275, 12399, 5296, 16254, 11296, 8717, 36178, 2423, 10721, 5172, 3615, 6027, 13, 8608, 2407, 16606, 25961, 21542, 4117, 20498, 3660, 12174, 2288, 2288, 2655, 11933, 11622, 6027, 3660, 6055, 3215, 5172, 3615, 11296, 34051, 11933, 11622, 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زيادة مطاولة الأسعار للأسعار والتي يعني زيادة مطاولة الأسعار ومن ثم أخرج المطاولة الأسعار ستزايد نفس الوظيفة زي زي زي زي زي زي زي", "tokens": [3224, 15730, 7251, 35457, 3555, 8978, 30767, 1829, 18513, 3660, 8978, 3714, 45636, 995, 22807, 30767, 1829, 18513, 3660, 3714, 9566, 995, 12610, 3660, 16247, 3794, 3615, 9640, 24976, 10721, 3794, 3615, 9640, 20328, 5016, 22807, 3714, 19913, 3555, 2407, 9566, 22807, 23758, 7251, 35457, 3555, 8978, 30767, 1829, 18513, 3660, 3714, 9566, 995, 12610, 3660, 16247, 3794, 3615, 9640, 24976, 10721, 3794, 3615, 9640, 16070, 31371, 37495, 22653, 30767, 1829, 18513, 3660, 3714, 9566, 995, 12610, 3660, 16247, 3794, 3615, 9640, 4032, 27842, 38637, 2304, 5551, 34740, 7435, 9673, 9566, 995, 12610, 3660, 16247, 3794, 3615, 9640, 8608, 2655, 11622, 995, 25708, 8717, 36178, 2423, 2407, 19913, 33911, 3660, 30767, 1829, 30767, 1829, 30767, 1829, 30767, 1829, 30767, 1829, 30767, 1829, 30767, 1829], "avg_logprob": -0.4799999856948853, "compression_ratio": 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زي", "probability": 0.6761474609375}, {"start": 1333.33, "end": 1333.33, "word": " زي", "probability": 0.6771240234375}, {"start": 1333.33, "end": 1333.61, "word": " زي", "probability": 0.81640625}, {"start": 1333.61, "end": 1333.63, "word": " زي", "probability": 0.893798828125}, {"start": 1333.63, "end": 1333.95, "word": " زي", "probability": 0.931884765625}], "temperature": 1.0}, {"id": 51, "seek": 136338, "start": 1334.76, "end": 1363.38, "text": "وهكذا ازالة المستخدم بقيمة MBC نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس الوضع نفس", "tokens": [2407, 3224, 4117, 15730, 1975, 11622, 6027, 3660, 9673, 14851, 9778, 40448, 4724, 4587, 32640, 3660, 376, 7869, 8717, 36178, 2423, 2407, 11242, 3615, 8717, 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Delta Y over Delta G instead of I equals one over one minus MBC that's it", "tokens": [36, 22345, 281, 437, 30, 18183, 398, 670, 18183, 460, 2602, 295, 286, 6915, 472, 670, 472, 3175, 376, 7869, 300, 311, 309], "avg_logprob": -0.5250650842984518, "compression_ratio": 1.0864197530864197, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 1363.97, "end": 1364.45, "word": "Equal", "probability": 0.236663818359375}, {"start": 1364.45, "end": 1364.61, "word": " to", "probability": 0.296142578125}, {"start": 1364.61, "end": 1364.77, "word": " what?", "probability": 0.4541015625}, {"start": 1365.51, "end": 1366.13, "word": " Delta", "probability": 0.75537109375}, {"start": 1366.13, "end": 1366.53, "word": " Y", "probability": 0.7841796875}, {"start": 1366.53, "end": 1366.83, "word": " over", "probability": 0.7900390625}, {"start": 1366.83, "end": 1367.21, "word": " Delta", "probability": 0.66015625}, {"start": 1367.21, "end": 1367.55, "word": " G", "probability": 0.94140625}, 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"text": "لذلك إذا قرر الحكومة تزيد خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها من خروجها", "tokens": [1211, 8848, 23275, 11933, 15730, 12174, 2288, 2288, 21542, 4117, 20498, 3660, 6055, 11622, 25708, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 2288, 29245, 11296, 9154, 16490, 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0.77850341796875}, {"start": 2508.23, "end": 2509.83, "word": " بالمعاملة", "probability": 0.42607421875}, {"start": 2509.83, "end": 2510.85, "word": " التجاربية", "probability": 0.5499755859375}, {"start": 2510.85, "end": 2511.81, "word": " في", "probability": 0.1900634765625}, {"start": 2511.81, "end": 2512.45, "word": " القصة", "probability": 0.683349609375}, {"start": 2512.45, "end": 2513.91, "word": " السابقة،", "probability": 0.781494140625}, {"start": 2513.91, "end": 2514.69, "word": " قلنا", "probability": 0.6868489583333334}, {"start": 2514.69, "end": 2515.07, "word": " أن", "probability": 0.3359375}, {"start": 2515.07, "end": 2515.59, "word": " المعاملة", "probability": 0.78485107421875}, {"start": 2515.59, "end": 2516.39, "word": " التجاربية", "probability": 0.950390625}, {"start": 2516.39, "end": 2516.77, "word": " يقوم", "probability": 0.16438802083333334}, {"start": 2516.77, "end": 2516.79, "word": " بإضافة", "probability": 0.5952392578125}, {"start": 2516.79, "end": 2517.39, "word": " C", "probability": 0.4873046875}, {"start": 2517.39, "end": 2517.75, "word": " إضافة", "probability": 0.7301025390625}, {"start": 2517.75, "end": 2518.73, "word": " I،", "probability": 0.6756591796875}, {"start": 2518.73, "end": 2519.97, "word": " ويحدث", "probability": 0.52264404296875}, {"start": 2519.97, "end": 2520.37, "word": " المعاملة", "probability": 0.5822296142578125}, {"start": 2520.37, "end": 2521.01, "word": " التجاربية", "probability": 0.94443359375}, {"start": 2521.01, "end": 2522.03, "word": " عندما", "probability": 0.82470703125}, {"start": 2522.03, "end": 2522.67, "word": " Y", "probability": 0.59619140625}, {"start": 2522.67, "end": 2523.65, "word": " يقوم", "probability": 0.3997395833333333}, {"start": 2523.65, "end": 2524.29, "word": " بالمعاملة", "probability": 0.733935546875}, {"start": 2524.29, "end": 2525.15, "word": " التجاربية", "probability": 0.980859375}], "temperature": 1.0}, {"id": 99, "seek": 254977, "start": 2526.05, "end": 2549.77, "text": "في هذه القصة سنعتقد أننا سنضع الحكومة كجزء من المبادرة، لذلك يجب أن يكون او المساعدة التجارية ستكون C plus I plus G، صحيح؟ لذلك في هذه الحالة، Y يجب أن يكون C plus I plus G، هذا هو الجزء الأول، صحيح؟", "tokens": [41185, 29538, 25062, 9381, 3660, 8608, 1863, 34268, 28543, 14739, 8315, 8608, 1863, 11242, 3615, 21542, 4117, 20498, 3660, 9122, 7435, 11622, 38207, 9154, 9673, 3555, 18513, 25720, 12399, 5296, 8848, 23275, 7251, 7435, 3555, 14739, 7251, 30544, 1975, 2407, 9673, 3794, 995, 22488, 3660, 16712, 7435, 9640, 10632, 8608, 2655, 30544, 383, 1804, 286, 1804, 460, 12399, 20328, 5016, 1829, 5016, 22807, 5296, 8848, 23275, 8978, 29538, 21542, 6027, 3660, 12399, 398, 7251, 7435, 3555, 14739, 7251, 30544, 383, 1804, 286, 1804, 460, 12399, 23758, 31439, 25724, 11622, 38207, 16247, 12610, 12399, 20328, 5016, 1829, 5016, 22807], "avg_logprob": -0.5287247534954187, "compression_ratio": 1.825136612021858, "no_speech_prob": 5.960464477539062e-07, "words": [{"start": 2526.05, "end": 2526.33, "word": "في", "probability": 0.291748046875}, {"start": 2526.33, "end": 2526.63, "word": " هذه", "probability": 0.39794921875}, {"start": 2526.63, "end": 2527.01, "word": " القصة", "probability": 0.5843912760416666}, {"start": 2527.01, "end": 2528.53, "word": " سنعتقد", "probability": 0.408416748046875}, {"start": 2528.53, "end": 2528.89, "word": " أننا", "probability": 0.65771484375}, {"start": 2528.89, "end": 2529.67, "word": " سنضع", "probability": 0.728271484375}, {"start": 2529.67, "end": 2530.51, "word": " الحكومة", "probability": 0.891357421875}, {"start": 2530.51, "end": 2531.37, "word": " كجزء", "probability": 0.7281494140625}, {"start": 2531.37, "end": 2531.59, "word": " من", "probability": 0.9853515625}, {"start": 2531.59, "end": 2532.59, "word": " المبادرة،", "probability": 0.34896240234375}, {"start": 2532.59, "end": 2533.33, "word": " لذلك", "probability": 0.6736653645833334}, {"start": 2533.33, "end": 2533.67, "word": " يجب", "probability": 0.7275390625}, {"start": 2533.67, "end": 2533.75, "word": " أن", "probability": 0.9033203125}, {"start": 2533.75, "end": 2533.97, "word": " يكون", "probability": 0.856201171875}, {"start": 2533.97, "end": 2534.19, "word": " او", "probability": 0.49188232421875}, {"start": 2534.19, "end": 2534.85, "word": " المساعدة", "probability": 0.5041259765625}, {"start": 2534.85, "end": 2535.05, "word": " التجارية", "probability": 0.5342254638671875}, {"start": 2535.05, "end": 2535.75, "word": " ستكون", "probability": 0.6434733072916666}, {"start": 2535.75, "end": 2536.45, "word": " C", "probability": 0.466552734375}, {"start": 2536.45, "end": 2536.89, "word": " plus", "probability": 0.0203704833984375}, {"start": 2536.89, "end": 2537.25, "word": " I", "probability": 0.9638671875}, {"start": 2537.25, "end": 2537.57, "word": " plus", "probability": 0.9296875}, {"start": 2537.57, "end": 2538.97, "word": " G،", "probability": 0.676513671875}, {"start": 2538.97, "end": 2539.35, "word": " صحيح؟", "probability": 0.7484130859375}, {"start": 2539.35, "end": 2540.03, "word": " لذلك", "probability": 0.6841634114583334}, {"start": 2540.03, "end": 2540.99, "word": " في", "probability": 0.82275390625}, {"start": 2540.99, "end": 2541.27, "word": " هذه", "probability": 0.619140625}, {"start": 2541.27, "end": 2541.87, "word": " الحالة،", "probability": 0.7296142578125}, {"start": 2541.87, "end": 2542.23, "word": " Y", "probability": 0.5791015625}, {"start": 2542.23, "end": 2542.67, "word": " يجب", "probability": 0.7888997395833334}, {"start": 2542.67, "end": 2542.69, "word": " أن", "probability": 0.880859375}, {"start": 2542.69, "end": 2543.05, "word": " يكون", "probability": 0.505615234375}, {"start": 2543.05, "end": 2543.43, "word": " C", "probability": 0.333984375}, {"start": 2543.43, "end": 2543.99, "word": " plus", "probability": 0.84375}, {"start": 2543.99, "end": 2544.51, "word": " I", "probability": 0.9921875}, {"start": 2544.51, "end": 2544.93, "word": " plus", "probability": 0.9599609375}, {"start": 2544.93, "end": 2545.73, "word": " G،", "probability": 0.7919921875}, {"start": 2545.73, "end": 2546.09, "word": " هذا", "probability": 0.392578125}, {"start": 2546.09, "end": 2546.49, "word": " هو", "probability": 0.73876953125}, {"start": 2546.49, "end": 2546.63, "word": " الجزء", "probability": 0.7349039713541666}, {"start": 2546.63, "end": 2548.11, "word": " الأول،", "probability": 0.90771484375}, {"start": 2548.11, "end": 2549.77, "word": " صحيح؟", "probability": 0.971875}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2550.7585, "duration_after_vad": 2422.378749999995}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/MuAhD8X0yHg.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/MuAhD8X0yHg.srt
new file mode 100644
index 0000000000000000000000000000000000000000..c461d7a4493297777c6cdfd5d6bf0f70fab6c555
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/MuAhD8X0yHg.srt
@@ -0,0 +1,2125 @@
+1
+00:00:20,990 --> 00:00:25,250
+بسم الله الرحمن الرحيم اليوم بإذن الله سنكمل
+
+2
+00:00:25,250 --> 00:00:29,490
+التعليمات الواقعية في القصة السادسة وربما إذا 
+
+3
+00:00:29,490 --> 00:00:34,010
+انتهينا سنذهب إلى التطبيقات أو التعليمات في القصة
+
+4
+00:00:34,010 --> 00:00:39,790
+السادسة، أليس كذلك؟ لذلك دعونا نكمل التعليمات كما
+
+5
+00:00:39,790 --> 00:00:45,740
+ترى في هذا الفيجور، أين الـ Equilibrium؟ في قيمة 5%
+
+6
+00:00:45,740 --> 00:00:51,480
+في هذه الحالة لا يوجد مقاومة ولا مصدر أو  Access من
+
+7
+00:00:51,480 --> 00:01:02,100
+المال في قيمة 3% هنا هنا
+
+8
+00:01:03,280 --> 00:01:10,260
+أو قيمة المال من قيمة المال من قيمة المال من قيمة
+
+9
+00:01:10,260 --> 00:01:17,260
+المال من قيمة المال من قيمة المال من قيمة المال من
+
+10
+00:01:17,260 --> 00:01:26,390
+قيمة المال 1200-800 طيب so at three here at the
+
+11
+00:01:26,390 --> 00:01:29,930
+interest rate of three percent there is a tendency
+
+12
+00:01:29,930 --> 00:01:32,130
+for interest rate to what? to increase or to
+
+13
+00:01:32,130 --> 00:01:34,810
+decrease? to increase to reach the equilibrium
+
+14
+00:01:34,810 --> 00:01:41,710
+right? but what about at the interest rate of eight?
+
+15
+00:01:41,710 --> 00:01:46,590
+there is what exactly? there is a surplus on money
+
+16
+00:01:46,590 --> 00:01:52,710
+supply by how much? 800 مليون - 400 مليون = 400 مليون 
+
+17
+00:01:52,710 --> 00:01:54,570
+400 مليون 400 مليون 400 مليون 400 مليون 400 مليون 400
+
+18
+00:01:54,570 --> 00:01:55,910
+مليون 400 مليون 400 مليون 400 مليون 400 مليون 400 مليون
+
+19
+00:01:55,910 --> 00:01:58,850
+400 مليون 400 مليون 400 مليون 400 مليون 400 مليون 400
+
+20
+00:01:58,850 --> 00:01:58,870
+مليون 400 مليون 400 مليون 400 مليون 400 مليون 400 مليون
+
+21
+00:01:58,870 --> 00:01:58,890
+400 مليون 400 مليون 400 مليون 400 مليون 400 مليون 400
+
+22
+00:01:58,890 --> 00:02:02,710
+مليون 400 مليون 400 مليون 400 مليون 400 مليون 400 مليون
+
+23
+00:02:02,710 --> 00:02:03,770
+400 مليون 400 مليون 400 مليون
+
+24
+00:02:07,930 --> 00:02:12,570
+العائلات والمؤسسات تفضل إلى ماذا؟ أو تفضل إلى ماذا؟
+
+25
+00:02:12,570 --> 00:02:19,190
+لتحمل أو لتشتري Bonds لأن عملياتهم عالية، صح؟ وهم
+
+26
+00:02:19,190 --> 00:02:26,690
+يحملون أقل المال، صح؟ لنذهب إلى التعامل كما ترى،
+
+27
+00:02:26,690 --> 00:02:32,900
+في عمليات 8%، هناك ماذا؟ دعونا نذهب إلى الإجابة،
+
+28
+00:02:32,900 --> 00:02:39,120
+الإجابة هي C  يميلون إلى 400 مليون دولار  يميلون إلى 400 مليون
+
+29
+00:02:39,120 --> 00:02:39,560
+دولار  يميلون إلى 400 مليون دولار  يميلون إلى 400 مليون دولار
+
+30
+00:02:39,560 --> 00:02:42,160
+يميلون إلى 400 مليون دولار يميلون إلى 400 مليون دولار يميلون إلى 400
+
+31
+00:02:42,160 --> 00:02:44,420
+مليون دولار يميلون إلى 400 مليون دولار يميلون إلى 400 مليون
+
+32
+00:02:44,420 --> 00:02:48,160
+دولار  يميلون إلى 400 مليون دولار يميلون إلى 400 مليون دولار
+
+33
+00:02:48,160 --> 00:02:50,480
+يميلون إلى 400 مليون دولار يميلون إلى 400 مليون دولار يميلون إلى 400
+
+34
+00:02:50,480 --> 00:02:51,020
+مليون دولار  يميلون إلى 400 مليون دولار يميلون إلى 400 مليون
+
+35
+00:02:51,020 --> 00:02:51,420
+دولار يميلون إلى 400 مليون دولار يميلون إلى 400 مليون دولار
+
+36
+00:02:51,420 --> 00:03:00,200
+يميلون إلى 400 مليون دولار يميلون إلى 400 مليون دولار يميلون إلى 400
+
+37
+00:03:00,200 --> 00:03:04,300
+مto what? الإجابة دي will attempt to reduce their
+
+38
+00:03:04,300 --> 00:03:07,660
+holding of money by إيش؟ buying bonds because the
+
+39
+00:03:07,660 --> 00:03:13,080
+interest rate is high صح؟ طيب at the interest rate
+
+40
+00:03:13,080 --> 00:03:16,260
+of three percent the firms and households tends to
+
+41
+00:03:16,260 --> 00:03:21,000
+what? to sell the bonds because the interest rate
+
+42
+00:03:21,000 --> 00:03:27,860
+is low صح؟ and they hold more cash أظبط ولا لأ؟
+
+43
+00:03:27,860 --> 00:03:33,050
+طيب at the interest rate of five الشركات والعائلات
+
+44
+00:03:33,050 --> 00:03:37,810
+مستمرة بذلك لأنه يوجد Equilibrium داخل الشركة داخل
+
+45
+00:03:37,810 --> 00:03:38,910
+الشركة داخل الشركة داخل الشركة داخل الشركة داخل
+
+46
+00:03:38,910 --> 00:03:42,150
+الشركة داخل
+
+47
+00:03:42,150 --> 00:03:42,810
+الشركة داخل الشركة داخل الشركة داخل الشركة داخل
+
+48
+00:03:42,810 --> 00:03:42,830
+الشركة داخل الشركة داخل الشركة داخل الشركة داخل
+
+49
+00:03:42,830 --> 00:03:43,050
+الشركة داخل الشركة داخل الشركة داخل الشركة داخل
+
+50
+00:03:43,050 --> 00:03:48,210
+الشركة داخل الشركة داخل الشركة داخل الشركة داخل
+
+51
+00:03:48,210 --> 00:03:50,290
+الشركة داخل الشركة داخل الشركة داخل الشركة داخل
+
+52
+00:03:50,290 --> 00:03:55,520
+الشركة داخل الشركة داخل ذلك السؤال هو إذا كان هناك
+
+53
+00:03:55,520 --> 00:04:01,460
+تقليل في مصادر المال و تقليل في GDP، ماذا سيحدث لـ
+
+54
+00:04:01,460 --> 00:04:05,060
+Equilibrium Interest Rate؟ هذا هو السؤال، التقليل
+
+55
+00:04:05,060 --> 00:04:10,200
+في مصادر المال يتسبب في زيادة R لأن هناك تغيير في
+
+56
+00:04:10,200 --> 00:04:16,030
+مصادر المال، مظبوط؟ ماذا بالنسبة لـ GDP؟ التخلص من
+
+57
+00:04:16,030 --> 00:04:19,990
+GDP يعني تخلص من الـ Y، تخلص من المال من المطالب،
+
+58
+00:04:19,990 --> 00:04:28,570
+تخلص من الـ R، فماذا ترى؟ مخلص أو غير متأكد؟ تخلص،
+
+59
+00:04:28,570 --> 00:04:34,970
+تخلص، فال .. كما ترى، إجابة الـ D هي إدارة على
+
+60
+00:04:34,970 --> 00:04:41,100
+مستوى الدولة الإيقليبية مخلص، صحيح؟ إذا قيمة المال
+
+61
+00:04:41,100 --> 00:04:45,160
+المطلوبة أكثر من قيمة المال المدفوعة، فرق الهدف
+
+62
+00:04:45,160 --> 00:04:54,940
+ماذا؟ دعنا نرسم و نقوم بالتحديث، هذا هو مدفوع
+
+63
+00:04:54,940 --> 00:05:00,320
+المال المطلوب، المسؤال هو إذا قيمة المال المطلوبة
+
+64
+00:05:00,320 --> 00:05:06,130
+أكثر أو أكثر من قيمة المال المدفوعة المال المطالب
+
+65
+00:05:06,130 --> 00:05:08,070
+هو أكثر من المال المصادر من المال المصادر من المال
+
+66
+00:05:08,070 --> 00:05:08,410
+المصادر من المال المصادر من المال المصادر من المال
+
+67
+00:05:08,410 --> 00:05:10,030
+المصادر من المال المصادر من المال المصادر من المال
+
+68
+00:05:10,030 --> 00:05:10,790
+المصادر من المال المصادر من المال المصادر من المال
+
+69
+00:05:10,790 --> 00:05:12,450
+المصادر من المال المصادر من المال المصادر من المال
+
+70
+00:05:12,450 --> 00:05:14,050
+المصادر من المال المصادر من المال المصادر من المال
+
+71
+00:05:14,050 --> 00:05:14,790
+المصادر من المال المصادر من المال المصادر من المال
+
+72
+00:05:14,790 --> 00:05:19,530
+المصادر من المال المصادر من المال المصادر من المال
+
+73
+00:05:19,530 --> 00:05:25,470
+المصادر من المال المصادر من المال المصادر من المال
+
+74
+00:05:25,470 --> 00:05:31,450
+المصادر من
+
+75
+00:05:31,450 --> 00:05:34,940
+المال the shortage هيك كمية  و money supply
+
+76
+00:05:34,940 --> 00:05:37,320
+demanded is greater than the quantity of money
+
+77
+00:05:37,320 --> 00:05:41,800
+supplied، شو بيعمل هذا؟ بيعمل increasing لل
+
+78
+00:05:41,800 --> 00:05:43,680
+equilibrium interest rate، هي زي ما أنتم شايفين
+
+79
+00:05:43,680 --> 00:05:48,440
+هيك، but what about the excess supply of money؟ لو
+
+80
+00:05:48,440 --> 00:05:51,060
+فيه أن ال .. يعني فيه أن ال excess supply of money
+
+81
+00:05:51,060 --> 00:05:54,100
+leads to a decreasing of the interest rate، أظبط
+
+82
+00:05:54,100 --> 00:06:00,470
+ولا لأ؟ السرفلاس في السوق يسبب فيه تقليل في قيمة
+
+83
+00:06:00,470 --> 00:06:07,210
+الدفع، أليس كذلك؟ دعنا نذهب إلى هذه ال figure إذا
+
+84
+00:06:07,210 --> 00:06:13,110
+كان هناك تغيير مصطلحي في قيمة الدفع، فهذا يعيد إلى
+
+85
+00:06:13,110 --> 00:06:21,780
+ماذا؟ تقليل قيمة الدفع والعكس من ذلك إذا كان هناك
+
+86
+00:06:21,780 --> 00:06:26,980
+تغيير في أحد المصادر من MS1 إلى MS2 ، فهذا يسبب في
+
+87
+00:06:26,980 --> 00:06:39,420
+زيادة في المستقبل ، فإذا كان هناك تدخل
+
+88
+00:06:40,830 --> 00:06:46,950
+أو خلّيني أروح للأسئلة Assume the interest rate
+
+89
+00:06:46,950 --> 00:06:50,710
+equals four يعني كان عندنا interest rate equals
+
+90
+00:06:50,710 --> 00:06:54,470
+four here تمام
+
+91
+00:06:54,470 --> 00:07:03,150
+and the money supply decreases from MS1 ل MS0 يعني
+
+92
+00:07:03,150 --> 00:07:07,130
+خلّيني أقول كنا هيك هذا ال equilibrium this is E1
+
+93
+00:07:07,130 --> 00:07:11,760
+وأجى أنه لقينا يعني صار في عندي leftward shifting
+
+94
+00:07:11,760 --> 00:07:16,860
+في ال money supply from MS1 ل MS0 أو Zero هذا شو
+
+95
+00:07:16,860 --> 00:07:19,440
+بيعمل في ال interest rate؟ would increase مظبوط
+
+96
+00:07:19,440 --> 00:07:25,740
+from 4 ل 6 but suppose .. السؤال بيقولنا suppose أن
+
+97
+00:07:25,740 --> 00:07:30,280
+ماصارش في عندي نقطة توازن جديدة و ال interest rate
+
+98
+00:07:30,280 --> 00:07:34,280
+remains constant عند 4 بمعنى أن صار في صحيح
+
+99
+00:07:34,280 --> 00:07:37,160
+shifting leftward shifting في ال money supply
+
+100
+00:07:37,160 --> 00:07:41,720
+curve تمام بس ال interest rate remains constant في
+
+101
+00:07:41,720 --> 00:07:44,720
+هذه الحالة في عندي excess supply ولا shortage
+
+102
+00:07:44,720 --> 00:07:48,180
+supply of money؟ shortage supply لأن هذا quantity
+
+103
+00:07:48,180 --> 00:07:50,380
+of money demanded وهذا quantity of money supplied
+
+104
+00:07:50,380 --> 00:07:53,880
+لأن money supply الجديد مظبوط؟ so there is what؟
+
+105
+00:07:53,880 --> 00:08:04,440
+a shortage مظبوط ولا لأ؟ طيب what else? yes أن
+
+106
+00:08:04,440 --> 00:08:09,220
+there is excess demand for money بالقيمة قديش؟ to
+
+107
+00:08:09,220 --> 00:08:14,240
+هو excess demand means shortage supply صح؟ of
+
+108
+00:08:14,240 --> 00:08:21,560
+قديش؟ 300 - 100 طيب لهذا
+
+109
+00:08:24,480 --> 00:08:40,060
+إذا تتقل من MS1 ل MS2، فإن
+
+110
+00:08:40,060 --> 00:08:42,820
+ال interest rate تتقل من 4 إلى 6
+
+111
+00:08:49,570 --> 00:08:53,910
+طيب الـ money supply curve تتغير من .. أو F ال
+
+112
+00:08:53,910 --> 00:08:59,750
+money supply curve تتغير من MS note ل MS one أو F
+
+113
+00:08:59,750 --> 00:09:05,630
+اكتشف ينطق الملحنة ال money supply curve من MS
+
+114
+00:09:05,630 --> 00:09:12,030
+note ل MS one خلينا نرجع لل diagram و نشوف من MS
+
+115
+00:09:12,030 --> 00:09:19,280
+note ل MS1 بمعنى increasing في ال money supply شو
+
+116
+00:09:19,280 --> 00:09:21,640
+ال .. شو ال determinants of the money supply
+
+117
+00:09:21,640 --> 00:09:26,940
+exactly? yes this is number one إذا decreasing the
+
+118
+00:09:26,940 --> 00:09:31,040
+required reserve ratio decreasing and the end ..
+
+119
+00:09:31,040 --> 00:09:34,440
+sorry the .. the discount rate and the last .. no
+
+120
+00:09:34,440 --> 00:09:38,320
+purchasing bonds buying bonds .. buying bonds
+
+121
+00:09:38,320 --> 00:09:41,940
+مظبوط؟ طيب نشوف ال .. ال answers
+
+122
+00:09:44,780 --> 00:09:49,380
+هيو .. إذا which one .. D is the .. the .. the
+
+123
+00:09:49,380 --> 00:09:52,120
+answer .. the .. the correct answer أن ال federal
+
+124
+00:09:52,120 --> 00:09:57,000
+بيعمل buying لل bonds، مظبوط؟ اللي اجرب C .. the
+
+125
+00:09:57,000 --> 00:09:59,360
+equilibrium level .. وين؟ .. the equilibrium level
+
+126
+00:09:59,360 --> 00:10:02,300
+of output increased اللي هو زيادة ال Y، شو بتعمل
+
+127
+00:10:02,300 --> 00:10:05,780
+increasing في ال Y؟ بتزود المانا ال demand و بتزود
+
+128
+00:10:05,780 --> 00:10:09,920
+ال R، مظبوط ولا لأ؟ صح؟ ما له علاقة من هناك، طيب
+
+129
+00:10:09,920 --> 00:10:16,880
+هذا حليناه ولا ما .. Okay على الـ shifting from MS1
+
+130
+00:10:16,880 --> 00:10:20,340
+to MS0F على الـ answer بإيه؟ اللي هو if the
+
+131
+00:10:20,340 --> 00:10:23,940
+federal increase the reserve requirement اللي هو
+
+132
+00:10:23,940 --> 00:10:27,540
+ال RRR required reserve ratio لو عملنا increasing
+
+133
+00:10:27,540 --> 00:10:32,100
+في required reserve ratio بيعمل decreasing في ال
+
+134
+00:10:32,100 --> 00:10:37,580
+money supply صح؟ تمام طيب ال money supply
+
+135
+00:10:37,580 --> 00:10:44,960
+increased من MS1 note to MS1 هذا أماله طبعا نعطينا
+
+136
+00:10:44,960 --> 00:10:50,160
+مجموعة إجابات نشوف ال answer بيه where the
+
+137
+00:10:50,160 --> 00:10:55,020
+interest rate will decrease to 4% نشوف عندنا
+
+138
+00:10:55,020 --> 00:11:01,960
+increasing from our supply من أيش لحظة من zero ل
+
+139
+00:11:01,960 --> 00:11:10,920
+MS1 من zero هيك هيعمل شو؟ هيعمل decreasing
+
+140
+00:11:12,960 --> 00:11:21,800
+decreasing من 6 لأربعة that's it صح؟ إذا
+
+
+
+141
+00:11:21,800 --> 00:11:24,720
+في عندنا surplus في الـ money supply شو بيبدأوا
+
+142
+00:11:24,720 --> 00:11:28,000
+بيعملوا؟ decrease the money supply لأنه أصلا في 
+
+143
+00:11:28,000 --> 00:11:31,520
+surplus في الـ money supply، مصبوح؟ that's it طيب
+
+144
+00:11:31,520 --> 00:11:34,660
+هذا حلناه اشتغلنا عليه اللي هو shortage في الـ
+
+145
+00:11:34,660 --> 00:11:37,640
+money supply أو في الـ money market شو بيعملوا فيه؟
+
+146
+00:11:37,640 --> 00:11:42,360
+increase the money supply that's it طيب و when the
+
+147
+00:11:42,360 --> 00:11:47,720
+federal sells government securities etc ..
+
+148
+00:11:47,720 --> 00:11:54,720
+peripers the money supply shifts to what؟ هلأ
+
+149
+00:11:54,720 --> 00:11:58,620
+بيعمل selling للـ bonds شو بيعمل selling للـ bonds؟
+
+150
+00:11:58,620 --> 00:12:01,320
+بينزل الـ money supply بيعمل leftward shifting في
+
+151
+00:12:01,320 --> 00:12:04,760
+الـ money supply، مظبوط؟ اذا .. and the interest
+
+152
+00:12:04,760 --> 00:12:06,840
+rate .. اذا خلينا نعمل selling للـ bonds
+
+153
+00:12:09,930 --> 00:12:12,810
+هذا بيعمل leftward shifting في الـ money supply
+
+154
+00:12:12,810 --> 00:12:16,990
+سهول interest rate would increase، that's it،
+
+155
+00:12:16,990 --> 00:12:22,110
+بسموه؟ طيب، decreasing the required reserve ratio،
+
+156
+00:12:22,110 --> 00:12:25,230
+هذا أخدناه كله، موضوع الـ required reserve ratio و
+
+157
+00:12:25,230 --> 00:12:28,310
+its impacts on the money supply، خلينا بس عشان
+
+158
+00:12:28,310 --> 00:12:32,930
+نمشي في الأسئلة، نحط القاعدة تبعتي، نشتغل عليها،
+
+159
+00:12:32,930 --> 00:12:35,290
+أنه ال increasing the required reserve ratio
+
+160
+00:12:36,250 --> 00:12:38,730
+decreasing the money supply and then the interest
+
+161
+00:12:38,730 --> 00:12:43,030
+rate would increase صح؟ طيب ال increasing في الـ
+
+162
+00:12:43,030 --> 00:12:45,830
+discount rate leads to decreasing the same
+
+163
+00:12:45,830 --> 00:12:50,450
+direction increasing R و ال selling bonds اللي هو 
+
+164
+00:12:50,450 --> 00:12:54,970
+الحالة الـ opposite case، مظبوط؟ عشان نمشي بالأسئلة
+
+165
+00:12:58,970 --> 00:13:02,350
+الإزالة في مستوى الإجارات المجاورة والشرطة التي 
+
+166
+00:13:02,350 --> 00:13:07,650
+تشترها من خلال الشركات المجاورة ستتأثر على إدارة
+
+167
+00:13:07,650 --> 00:13:13,130
+الإيقاليبرام لأن الشرطة التي تشتر في مستوى
+
+168
+00:13:13,130 --> 00:13:15,070
+الإجارات المجاورة يعني الشركة التي تشتر في الـY
+
+169
+00:13:15,070 --> 00:13:18,530
+مستوى
+
+170
+00:13:18,530 --> 00:13:23,010
+الإجارات المجاورة ستتأثر على مستوى الـR
+
+171
+00:13:24,770 --> 00:13:27,430
+طيب في نفس الوقت في اندي purchasing of the 
+
+172
+00:13:27,430 --> 00:13:30,230
+government securities purchasing bonds شو بتعمل في 
+
+173
+00:13:30,230 --> 00:13:39,130
+الـ money supply انا purchasing buying bonds or
+
+174
+00:13:39,130 --> 00:13:41,450
+the government securities leads to increasing
+
+175
+00:13:41,450 --> 00:13:44,490
+money supply leads to a decreasing in R so
+
+176
+00:13:44,490 --> 00:13:49,850
+indeterminate effect on the interest rate يعني غير
+
+177
+00:13:49,850 --> 00:13:55,890
+محدد صح الـ R غير محدد لأنه انا increasing اللي هو
+
+178
+00:13:55,890 --> 00:14:01,190
+ambiguous yes and determinate means ambiguous طيب
+
+179
+00:14:01,190 --> 00:14:05,710
+which of the following pairs of events will
+
+180
+00:14:05,710 --> 00:14:08,230
+definitely lead to increasing the equilibrium
+
+181
+00:14:08,230 --> 00:14:11,090
+interest rate؟ شو اللي بيعمل مؤكد أنه يزيد الـ
+
+182
+00:14:11,090 --> 00:14:15,330
+interest rate؟ هم يعطييني مجموعة alternatives تمام
+
+183
+00:14:15,330 --> 00:14:18,890
+خلينا ناخد ايه نجرب بعدين ما زبطش بيروح الـ BISC
+
+184
+00:14:18,890 --> 00:14:22,890
+and so on جرب الأول the sale of the government
+
+185
+00:14:22,890 --> 00:14:28,180
+securities by the federal اللي هو
+
+186
+00:14:28,180 --> 00:14:32,780
+selling bonds بيعمل
+
+187
+00:14:32,780 --> 00:14:36,140
+decreasing للـ money supply and increasing R this is
+
+188
+00:14:36,140 --> 00:14:40,740
+the first one طيب هلأ في الجوان نفسه شو بيعطيني؟
+
+189
+00:14:40,740 --> 00:14:44,400
+buy further resources and increase in the price
+
+190
+00:14:44,400 --> 00:14:49,610
+level الـ increasing in the price level Exactly,
+
+191
+00:14:49,790 --> 00:14:54,930
+increase the money demand, increase R For sure, R
+
+192
+00:14:54,930 --> 00:14:59,430
+would increase طب جرب بي مش هتظبط لأنها بي
+
+193
+00:14:59,430 --> 00:15:03,830
+decrease في ايش؟ discount rate دي this is answer A
+
+194
+00:15:03,830 --> 00:15:08,430
+let's go to answer B decrease in the discount rate
+
+195
+00:15:08,430 --> 00:15:13,470
+شو بيعمل؟ بيعمل increasing money supply increasing
+
+196
+00:15:13,470 --> 00:15:19,070
+sorry decreasing R اذا هذا مش ظابط بس جرب كمان and
+
+197
+00:15:19,070 --> 00:15:23,290
+and increase in aggregate output أعمل increasing
+
+198
+00:15:23,290 --> 00:15:29,410
+في الـ Y increase money demand increase R هنا هيكون
+
+199
+00:15:29,410 --> 00:15:34,210
+ambiguous جرب في كل الـ cases مش هيظبط إلا إيه صح؟
+
+200
+00:15:36,990 --> 00:15:42,270
+I know فيهم definitely مؤكدا leads or to decrease
+
+201
+00:15:42,270 --> 00:15:44,870
+in the equilibrium interest rate بداك تجرب كل الـ
+
+202
+00:15:44,870 --> 00:15:48,730
+cases بس هو ميعطينا الـ answer C ان هو اللي هي نجرب
+
+203
+00:15:48,730 --> 00:15:54,010
+الـ C و نشوف شوله ده او جرب A و بعدين نجرب C جرب A
+
+204
+00:15:54,010 --> 00:16:03,110
+نعم جرب C جرب C okay C
+
+205
+00:16:03,110 --> 00:16:07,720
+decreasing in the required reserve ratio increasing
+
+206
+00:16:07,720 --> 00:16:13,520
+money supply decreasing R بعدين في نفس الـ answer
+
+207
+00:16:13,520 --> 00:16:18,200
+and decreasing the aggregate output decreasing Y
+
+208
+00:16:18,200 --> 00:16:24,120
+decrease money demand decreasing R so definitely R
+
+209
+00:16:24,120 --> 00:16:28,800
+would decline جرب في الـ other cases مش هيظبط
+
+210
+00:16:35,570 --> 00:16:40,840
+هذا أخدنا زيه the same بتعرفوا إزاي تتطبقوا على هذا
+
+211
+00:16:40,840 --> 00:16:43,600
+الأمور ولا لأ؟ ولا لسه فيه حاجة لـ exercises
+
+212
+00:16:43,600 --> 00:16:47,540
+بالموضوع هذا؟ خليني أستكمل طيب عندي decreasing and
+
+213
+00:16:47,540 --> 00:16:52,500
+the aggregate output decreasing aggregate output a
+
+214
+00:16:52,500 --> 00:16:54,860
+citrus purpose مع بقاء العوامل الأخرى على حالها
+
+215
+00:16:54,860 --> 00:16:58,500
+will cause the demand for money to work and the
+
+216
+00:16:58,500 --> 00:17:02,630
+interest rate to work خلينا نشوف Decreasing in Y
+
+217
+00:17:02,630 --> 00:17:06,150
+Leads to Decreasing in Money Demand Decreasing in
+
+218
+00:17:06,150 --> 00:17:13,270
+R فهنا Decreasing and Decreasing An
+
+219
+00:17:13,270 --> 00:17:16,950
+increase in the price level etc purpose will cause
+
+220
+00:17:16,950 --> 00:17:19,210
+the demand for money to what and the interest rate
+
+221
+00:17:19,210 --> 00:17:24,250
+to what? Increase in the prices P leads to
+
+222
+00:17:24,250 --> 00:17:27,770
+increasing money demand increasing R that's it so
+
+223
+00:17:27,770 --> 00:17:28,430
+increase increase
+
+224
+00:17:31,780 --> 00:17:34,520
+as the number of transactions in the economy
+
+225
+00:17:34,520 --> 00:17:37,940
+decreased the number of transactions decreased
+
+226
+00:17:37,940 --> 00:17:42,480
+number of transactions decreased هذا شو بيعمل
+
+227
+00:17:42,480 --> 00:17:46,240
+بيعمل decreasing في الـ money demand مظبوط ولا لأ
+
+228
+00:17:46,240 --> 00:17:49,640
+decreasing
+
+229
+00:17:49,640 --> 00:17:54,500
+are في النجابات هي decrease في الـ money demand
+
+230
+00:17:57,680 --> 00:18:00,920
+Which of the following event will lead to a
+
+231
+00:18:00,920 --> 00:18:03,260
+decrease in the equilibrium interest rate؟ بتاكي
+
+232
+00:18:03,260 --> 00:18:07,680
+تجرب في هدولة و تشوف لما يعطينا answer B، جرب فيه،
+
+233
+00:18:07,680 --> 00:18:11,420
+decreasing in required reserve ratio، but that's
+
+234
+00:18:11,420 --> 00:18:14,820
+it يعني عندنا decreasing في required reserve
+
+235
+00:18:14,820 --> 00:18:18,860
+ratio، شو بيعمل؟ increasing في الـ money supply،
+
+236
+00:18:18,860 --> 00:18:23,240
+decreasing R هذا answer فهو ايش اللي هيبقى فينا
+
+237
+00:18:23,240 --> 00:18:25,620
+decreasing في الـ equilibrium interest rate جرب في
+
+238
+00:18:25,620 --> 00:18:29,320
+بيه في ايه increase في الـ aggregate output الـ Y
+
+239
+00:18:29,320 --> 00:18:31,820
+increasing Y بيعمل شو increasing money demand
+
+240
+00:18:31,820 --> 00:18:37,820
+increasing R فهو مش هيظبط okay
+
+241
+00:18:37,820 --> 00:18:42,120
+the same okay and the period of high inflation
+
+242
+00:18:42,120 --> 00:18:46,420
+rate اذا في انا high inflation rate يعني مع الكلام
+
+243
+00:18:46,420 --> 00:18:50,020
+الـ money supply كتير مظبوط؟ هلأ شو لازم تعمل الـ
+
+244
+00:18:50,020 --> 00:18:54,860
+federal؟ ميعطيني أكتر من answer لازم نزل الـ money
+
+245
+00:18:54,860 --> 00:18:59,800
+supply الـ federal has to decrease the money supply
+
+246
+00:18:59,800 --> 00:19:02,160
+to solve the high unemployment rate او to decrease
+
+247
+00:19:02,160 --> 00:19:04,560
+the high unemployment rate اي sorry the inflation
+
+248
+00:19:04,560 --> 00:19:07,460
+rate اذا الـ inflation rate معناه انه في money
+
+249
+00:19:07,460 --> 00:19:10,850
+supply كتير كيبنا نحله و بدنا ننزله طب شو الـ tools
+
+250
+00:19:10,850 --> 00:19:13,710
+اللي ممكن استخدمها عشان ينزل الـ money supply؟ يا
+
+251
+00:19:13,710 --> 00:19:16,230
+بدنا نرفع نزيد increasing the required reserve
+
+252
+00:19:16,230 --> 00:19:20,330
+ratio increasing the discount rate or selling
+
+253
+00:19:20,330 --> 00:19:25,990
+bonds which one؟ الـ P اللي هو الـ tight monetary
+
+254
+00:19:25,990 --> 00:19:29,330
+policy tight monetary policy معناه سياسة نقدية
+
+255
+00:19:29,330 --> 00:19:33,270
+انكماشية يعني بدأ أقلل الـ money supply هذا اللي هو
+
+256
+00:19:33,270 --> 00:19:36,190
+by increasing the required reserve ratio discount
+
+257
+00:19:36,190 --> 00:19:40,140
+rate طيب في حالات الـ high unemployment rate شو
+
+258
+00:19:40,140 --> 00:19:47,020
+بيعملوا؟ بيعملوا ease monetary policy سياسة نقدية
+
+259
+00:19:47,020 --> 00:19:49,660
+توسعية بيزودوا .. they .. they have to increase
+
+260
+00:19:49,660 --> 00:19:55,220
+the money supply تمام طبعا
+
+261
+00:19:55,220 --> 00:20:01,700
+ease or when the economists refer to ease ease
+
+262
+00:20:01,700 --> 00:20:03,760
+means توسعي
+
+263
+00:20:08,150 --> 00:20:16,110
+AC Monetary Policy يعني أن الوزيرات تأخذ حركة تحفظ 
+
+264
+00:20:16,110 --> 00:20:23,610
+الموارد التي تحفظ الموارد التي تحفظ الموارد التي 
+
+265
+00:20:23,610 --> 00:20:27,090
+تحفظ الموارد التي تحفظ الموارد التي تحفظ
+
+266
+00:20:27,090 --> 00:20:27,350
+التي تحفظ الموارد التي تحفظ الموارد التي تحفظ
+
+267
+00:20:27,350 --> 00:20:30,790
+التي تحفظ الموارد
+
+268
+00:20:33,600 --> 00:20:37,040
+Contractionary monetary policy means withdrawing
+
+269
+00:20:37,040 --> 00:20:39,660
+the money supply or decreasing the money supply
+
+270
+00:20:39,660 --> 00:20:45,220
+بصح؟ By selling bonds, by decreasing .. sorry
+
+271
+00:20:45,220 --> 00:20:47,740
+increasing the required reserve ratio, increasing
+
+272
+00:20:47,740 --> 00:20:54,070
+the discount rate بصح؟ طيب، which is an example of
+
+273
+00:20:54,070 --> 00:20:58,070
+the tight monetary policy؟ أنه من هدول هو مثال على
+
+274
+00:20:58,070 --> 00:21:02,790
+tight or contractionary monetary policy بيقود لتقليل،
+
+275
+00:21:02,790 --> 00:21:07,630
+decreasing في الـ money supply جرب أي واحد number
+
+276
+00:21:07,630 --> 00:21:10,270
+one decrease the required reserve ratio لو عملنا
+
+277
+00:21:10,270 --> 00:21:13,310
+decreasing the required reserve ratio decreasing
+
+278
+00:21:13,310 --> 00:21:16,110
+required reserve ratio بيعمل increasing في الـ
+
+279
+00:21:16,110 --> 00:21:19,270
+money supply وبتالي هذا ايش ماله expansionary او
+
+280
+00:21:19,270 --> 00:21:23,630
+easy monetary policy وبتالي مش هيظبط جرب بي selling 
+
+281
+00:21:23,630 --> 00:21:28,750
+government securities هذا مظبوط طيب أنوا فيهم an
+
+282
+00:21:28,750 --> 00:21:32,450
+example of tight monetary policy tight means
+
+283
+00:21:32,450 --> 00:21:37,030
+contraction وبالتالي شو اللي بيعمل decreasing لل
+
+284
+00:21:37,030 --> 00:21:41,330
+money supply اللي
+
+285
+00:21:41,330 --> 00:21:44,530
+هو increase في required reserve ratio بيعمل 
+
+286
+00:21:44,530 --> 00:21:49,730
+decreasing في ال money supply طيب let's go to a
+
+287
+00:21:49,730 --> 00:21:52,950
+chapter or to the applications on chapter 8
+
+288
+00:21:56,720 --> 00:22:04,660
+لنذهب إلى التعليقات أو التعليقات في القسم 8 رقم
+
+289
+00:22:04,660 --> 00:22:09,190
+1The market in which the equilibrium level of
+
+290
+00:22:09,190 --> 00:22:12,490
+aggregate output is determined is what؟ هذا ال
+
+291
+00:22:12,490 --> 00:22:16,510
+goods and services market ولا ال money market؟ أيه
+
+292
+00:22:16,510 --> 00:22:18,830
+اللي بتحدد فيه ال equilibrium level of aggregate
+
+293
+00:22:18,830 --> 00:22:22,270
+output؟ ال goods market طب أيه اللي بتحدد فيه ال
+
+294
+00:22:22,270 --> 00:22:26,010
+interest rate؟ ال money market money demand money
+
+295
+00:22:26,010 --> 00:22:26,830
+supply؟
+
+296
+00:22:31,300 --> 00:22:37,780
+إذا كانت الاستثمار المخطط لتغيير
+
+297
+00:22:37,780 --> 00:22:41,520
+الاستثمار في الاستثمار الواقعي أنا أرجعكم شوية على
+
+298
+00:22:41,520 --> 00:22:48,700
+ال crowding out عشان نقدر نمشي ال crowding out إذا
+
+299
+00:22:48,700 --> 00:22:55,440
+كنتم تذكرون هو
+
+300
+00:22:55,440 --> 00:23:00,010
+خلق due to what؟ to the expansion of fiscal policy
+
+301
+00:23:00,010 --> 00:23:04,070
+or expansion of monetary policy مظبوط؟ صح؟ طيب ال
+
+302
+00:23:04,070 --> 00:23:06,850
+expansion of fiscal policy means increasing the
+
+303
+00:23:06,850 --> 00:23:09,330
+government spending which leads or decreasing the
+
+304
+00:23:09,330 --> 00:23:13,090
+taxes leads to increasing aggregate expenditure
+
+305
+00:23:13,090 --> 00:23:19,590
+increasing Y increasing money demand increasing R
+
+306
+00:23:19,590 --> 00:23:26,270
+decreasing I decreasing aggregate expenditure with
+
+307
+00:23:26,270 --> 00:23:32,610
+the small decreasing y with the small هلأ قولنا
+
+308
+00:23:32,610 --> 00:23:38,930
+إيش؟ أنه ال crowding out وين ظهر؟ ظهر نتيجة أن ال
+
+309
+00:23:38,930 --> 00:23:43,570
+interest rate increased و أثر على ال investment
+
+310
+00:23:43,570 --> 00:23:47,670
+نزله شوية، مظبوط؟ مش هذه مشكلة crowding out
+
+311
+00:23:47,670 --> 00:23:54,110
+فاكرينها؟ طيب، هلأ إذا كان الـ investment is not
+
+312
+00:23:54,110 --> 00:23:58,950
+responsive for the interest rate يعني ما فيش علاقة
+
+313
+00:23:58,950 --> 00:24:01,790
+ما بين ال investment و ال interest rate يعني لو
+
+314
+00:24:01,790 --> 00:24:06,630
+رفعنا ال interest rate ب 10% هي increasing by 10%
+
+315
+00:24:06,630 --> 00:24:11,470
+و هذا decreased by 0 ما فيش علاقة بين التانية بيكون
+
+316
+00:24:11,470 --> 00:24:13,990
+ال investment .. the planned investment curve is
+
+317
+00:24:13,990 --> 00:24:17,750
+vertical line so there is unresponsive for the
+
+318
+00:24:17,750 --> 00:24:21,530
+planned investment to the interest rate ما فيش رد ..
+
+319
+00:24:21,530 --> 00:24:25,410
+ما فيش reaction .. ما فيش رد التفعل أو .. اللي هو رد
+
+320
+00:24:25,410 --> 00:24:28,390
+.. أو يعني خلّيني أقول رد من ال investment لل
+
+321
+00:24:28,390 --> 00:24:31,570
+interest rate وبتالي crowding out شو بيصير فيه؟
+
+322
+00:24:31,570 --> 00:24:35,150
+Zero .. مظبوط؟ ما فيش عنده مشكلة crowding out لأن
+
+323
+00:24:35,150 --> 00:24:40,460
+ال Y ما نزلش هنا إذا كان الوضع هيك بيكون الـ Planned
+
+324
+00:24:40,460 --> 00:24:43,980
+Investment للانزول فيه يساوي Zero and Zero in Y
+
+325
+00:24:43,980 --> 00:24:48,380
+وبالتالي بيظلني على نفس ال increasing الأساسي صح؟
+
+326
+00:24:48,380 --> 00:24:51,040
+أنه زي ما أنا مخطط إذا أنا بدأ أزيد الناتج ب 200
+
+327
+00:24:51,040 --> 00:24:56,960
+هيزيد ب 200 مش هيرجع ينزل بشوية مش هيك الوضع؟ صح؟
+
+328
+00:24:56,960 --> 00:25:01,280
+طب في هذه الحالة in this case يعني suppose إنه إذا
+
+329
+00:25:01,280 --> 00:25:03,980
+كان الـ Planned Investment curve جاي هيك
+
+330
+00:25:07,140 --> 00:25:13,840
+هذا في مرحلة استثمارات مختلفة وإزالة في R لن تتغير
+
+331
+00:25:13,840 --> 00:25:23,840
+I المجتمع يخرج ماذا؟ نصف وهناك غير مجتمع لأستثمار
+
+332
+00:25:23,840 --> 00:25:31,160
+أو لأستثمار أو لتغيير الاستثمار، أصبح؟ طيب، سؤالي
+
+333
+00:25:31,160 --> 00:25:35,100
+هو R I
+
+334
+00:25:37,900 --> 00:25:42,900
+الـ monetary policy is it effective or ineffective؟
+
+335
+00:25:42,900 --> 00:25:48,300
+ineffective exactly صح؟ لأن هذا ال interest ليه
+
+336
+00:25:48,300 --> 00:25:51,140
+تقلي علاقة بالإيش؟ بال monetary policy وبالتالي ما
+
+337
+00:25:51,140 --> 00:25:54,320
+أثرش إذا هو .. إذا ال monetary policy مالها is
+
+338
+00:25:54,320 --> 00:26:01,340
+ineffective مش فعال صح؟ إذا مين الفعال عندي؟ ال
+
+339
+00:26:01,340 --> 00:26:04,880
+fiscal policy لأنه أنا مخطط أزود الناتج سب وزنه ب
+
+340
+00:26:04,880 --> 00:26:10,380
+200وزاد الناتج بالـ 200 مليون ما نزلش، إذا الـ
+
+341
+00:26:10,380 --> 00:26:15,100
+fiscal policy is effective، if the planned
+
+342
+00:26:15,100 --> 00:26:18,200
+investment curve is a vertical line، the crowding
+
+343
+00:26:18,200 --> 00:26:21,720
+out is zero، there is unresponsiveness for the
+
+344
+00:26:21,720 --> 00:26:24,640
+change or the perfectly unresponsiveness to that
+
+345
+00:26:24,640 --> 00:26:28,000
+change، changes in the interest rate اللي هو ال
+
+346
+00:26:28,000 --> 00:26:31,780
+planned investment مش يعني ما فيش ال responsiveness لل
+
+347
+00:26:31,780 --> 00:26:35,020
+interest rate، مظبوط؟ ال change in interest rate
+
+348
+00:26:35,020 --> 00:26:39,180
+وكمان the fiscal policy is effective and the
+
+349
+00:26:39,180 --> 00:26:43,540
+monetary policy is ineffective، مظبوط؟ طيب خلينا
+
+350
+00:26:43,540 --> 00:26:48,800
+نروح لل exercisesاللأ if the planned investment is
+
+351
+00:26:48,800 --> 00:26:52,660
+perfectly unresponsive to that change in the
+
+352
+00:26:52,660 --> 00:26:55,360
+interest rate، the planned investment curve أشماله
+
+353
+00:26:55,360 --> 00:26:59,120
+is a vertical line، بصبوح؟ طيب إذا كان الوضع هيك
+
+354
+00:26:59,120 --> 00:27:03,220
+perfectly responsive to that change in the
+
+355
+00:27:03,220 --> 00:27:05,980
+interest rate، بيكون أشماله horizontal line،
+
+356
+00:27:05,980 --> 00:27:13,730
+that's it، بصبوح؟إذا كانت الاستثمارات مناسبة
+
+357
+00:27:13,730 --> 00:27:18,430
+للتغيير في قيمة الانترنت، فإن قطرة الاستثمارات هي
+
+358
+00:27:18,430 --> 00:27:23,570
+حالة عيونية، وهي هذا السؤال. ماذا إذا كانت
+
+359
+00:27:23,570 --> 00:27:29,490
+المقالات التالية تمثل ايقاليبرام في عمليات السوق؟
+
+360
+00:27:29,490 --> 00:27:38,410
+Y إيقال C بلس I بلس G، هذا هو، مظبوط؟ طب هذا له
+
+361
+00:27:38,410 --> 00:27:45,030
+لقب مين؟money market بصبوط طيب let's go to this
+
+362
+00:27:45,030 --> 00:27:51,710
+example هذا
+
+363
+00:27:51,710 --> 00:27:54,010
+السؤال مهم و شوية و بدنا نركز فيه
+
+364
+00:27:57,070 --> 00:28:03,390
+لدينا قيمة مختلفة للقيمة والاستثمارات عندما تقوم
+
+365
+00:28:03,390 --> 00:28:08,430
+الاستثمارات بقيمة ثلاثة فالاستثمارات 400 هذا يغير
+
+366
+00:28:08,430 --> 00:28:14,330
+الاستثمارات ويعني اتقال في الاستثمارات مظموم؟ هل
+
+367
+00:28:14,330 --> 00:28:17,850
+يشايفون أن هناك علاقة عكسية أو علاقة ناجحة بين
+
+368
+00:28:17,850 --> 00:28:21,950
+قيمة الاستثمارات والاستثمارات مظموم؟ حسنا دعونا
+
+369
+00:28:21,950 --> 00:28:23,210
+نشوف التعليقات
+
+370
+00:28:25,400 --> 00:28:28,260
+refer to the table if the interest rate dropped
+
+371
+00:28:28,260 --> 00:28:34,640
+from 15% to 6% the planned investment would it
+
+372
+00:28:34,640 --> 00:28:37,740
+change by how much? decrease ولا increase by how
+
+373
+00:28:37,740 --> 00:28:41,280
+much؟ هلأ أن ال decreasing في ال interest rate من
+
+374
+00:28:41,280 --> 00:28:46,100
+15% ل 6% إذا أكيد هيزيد ال investment، مظبوط؟ so
+
+375
+00:28:46,100 --> 00:28:48,600
+it should increase by how much؟ خليني نرجع لل
+
+376
+00:28:48,600 --> 00:28:55,890
+table هذا من 15% ل 6%؟ قد ايش اندي لـ Planned
+
+377
+00:28:55,890 --> 00:29:01,230
+Investment هيتغير من 240 لـ 360 سوف ياندي
+
+378
+00:29:01,230 --> 00:29:10,850
+increasing by 120 صح بما يقابلها طيب let's go to
+
+379
+00:29:10,850 --> 00:29:15,710
+this question suppose
+
+380
+00:29:15,710 --> 00:29:22,550
+that expenditure multiplier is 3 An increase in the
+
+381
+00:29:22,550 --> 00:29:29,590
+interest rate from 6% to 9% etc.'s purpose would
+
+382
+00:29:29,590 --> 00:29:33,710
+what؟ إيش بيعملها؟ هلأ خليني أرجع لل formula تبعت
+
+383
+00:29:33,710 --> 00:29:37,010
+ال multiplier فاكرين ال multiplier؟ multiplier
+
+384
+00:29:37,010 --> 00:29:41,550
+Delta
+
+385
+00:29:41,550 --> 00:29:49,910
+Y over Delta I صح؟ اللي هو multiplier it's given
+
+386
+00:29:49,910 --> 00:29:55,410
+here كده إيش؟ three equals
+
+387
+00:29:55,410 --> 00:30:06,190
+delta y unknown over إنا إيش صار؟ في إنا increase
+
+388
+00:30:06,190 --> 00:30:09,910
+من .. في ال interest rate من ستة لتسعة إذاً كده
+
+389
+00:30:09,910 --> 00:30:14,010
+إيش صار؟ في عندي تغير في ال investment هينزل من
+
+390
+00:30:14,010 --> 00:30:18,870
+تسعة لستة لحظة من تسعة لستة من تسعة لستة من تسعة
+
+391
+00:30:18,870 --> 00:30:21,310
+لستة من تسعة لستة من تسعة لستة من تسعة
+
+392
+00:30:21,310 --> 00:30:26,790
+لستة من تسعة لستة من تسعة لستة من تسعة لستة
+
+393
+00:30:26,790 --> 00:30:26,930
+من تسعة لستة من تسعة لستة من تسعة لستة من تسعة
+
+394
+00:30:26,930 --> 00:30:27,450
+لستة من تسعة لستة من تسعة لستة من تسعة لستة من
+
+395
+00:30:27,450 --> 00:30:30,910
+تسعة لستة من تسعة لستة من تسعة لستة من تسعة لستة
+
+396
+00:30:30,910 --> 00:30:31,550
+من تسعة لستة من تسعة لستة من تسعة لستة من تسعة
+
+397
+00:30:31,550 --> 00:30:31,670
+لستة من تسعة لستة من تسعة لستة من تسعة لستة من
+
+398
+00:30:31,670 --> 00:30:38,050
+تسعة لستة من تسعة
+
+399
+00:30:38,050 --> 00:30:44,170
+لستبصبوح صح ما بتبدأش تستخدم ال formula هيك three هذا
+
+400
+00:30:44,170 --> 00:30:47,870
+على I I two minus I one هيك القانون I one I two
+
+401
+00:30:47,870 --> 00:30:52,150
+minus I one صح مش delta I equals اللي هي I two
+
+402
+00:30:52,150 --> 00:30:56,890
+minus I one طبّق على القانون هذا three equals delta
+
+403
+00:30:56,890 --> 00:31:05,950
+Y over I two قداش 320 minus 360
+
+404
+00:31:08,820 --> 00:31:17,180
+بعد ذلك 3 أقل لديلتا Y أقل من 40 لديلتا Y أقل من
+
+405
+00:31:17,180 --> 00:31:21,500
+120 لدينا أقل من 120 لدينا أقل من 120 لدينا
+
+406
+00:31:30,830 --> 00:31:35,230
+الجواب هو C ، وهناك أقل في ميزة الاستخدام بميزة
+
+407
+00:31:35,230 --> 00:31:44,710
+120 مليون دولار ، دعنا نذهب إلى هذه السؤال ، فإذا
+
+408
+00:31:44,710 --> 00:31:51,310
+كانت الميزة مرتبطة 4 مرتبطة
+
+409
+00:31:51,310 --> 00:31:54,630
+مرتبطة 4 مرتبطة مرتبطة مرتبطة مرتبطة مرتبطة مرتبطة
+
+410
+00:31:54,630 --> 00:31:56,070
+مرتبطة مرتبطة مرتبطة مرتبطة مرتبطة مرتبطة مرتبطة
+
+411
+00:32:05,840 --> 00:32:19,560
+نفس السؤال نفس السؤال نفس
+
+412
+00:32:19,560 --> 00:32:19,640
+السؤال نفس السؤال نفس السؤال نفس السؤال نفس السؤال
+
+413
+00:32:19,640 --> 00:32:24,110
+نفس السؤال 12 يعني خلّيني نشوف ال information لو ده
+
+414
+00:32:24,110 --> 00:32:30,110
+أطبّق هذا هيك Y2-Y1 over I2-I1 هذا ال formula اللي
+
+415
+00:32:30,110 --> 00:32:36,890
+هو ال multiplier equals Y2-Y1 over I2-I1 خلّيني
+
+416
+00:32:36,890 --> 00:32:38,950
+نطبّق و نشوف شو ال information اللي معطلينيها
+
+417
+00:32:38,950 --> 00:32:43,750
+بقولنا ال multiplier equals 5 تمام هده بنسميها هيك
+
+418
+00:32:43,750 --> 00:32:47,890
+multiplier multiplier
+
+419
+00:32:49,380 --> 00:32:53,560
+Equals 5 شو مقبلي كمان The initial interest rate
+
+420
+00:32:53,560 --> 00:33:05,240
+is 12 يعني R1 Equals 12 مظبوط؟ طيب A move to what
+
+421
+00:33:05,240 --> 00:33:08,280
+interest rate will increase the equilibrium output
+
+422
+00:33:08,280 --> 00:33:17,160
+by 400 يعني Delta Y Equals 400 Delta Y Equals 400
+
+423
+00:33:18,710 --> 00:33:24,550
+خلينا نشتغل multiplier لو 5 equals delta y
+
+424
+00:33:24,550 --> 00:33:34,290
+positive 400 over I2 minus I1  والـ R1 equals 12%
+
+425
+00:33:34,290 --> 00:33:37,150
+جدّيش الـ I1 بدي أرجع للـ table هيك
+
+426
+00:33:40,290 --> 00:33:47,830
+and r equals twelve قداش الـ investment 280 so
+
+427
+00:33:47,830 --> 00:33:59,390
+خلينا نعمل تعويض 280 اشتغل هيك five times five
+
+428
+00:33:59,390 --> 00:34:05,550
+times I two minus 280 equals 400
+
+429
+00:34:22,240 --> 00:34:29,160
+5I2-5I2-5I2
+
+430
+00:34:29,160 --> 00:34:35,320
+-5I2
+
+431
+00:34:37,120 --> 00:34:50,420
+I2 أكثر من 280 أكثر من 280 أكثر من 360 أكثر
+
+432
+00:34:50,420 --> 00:34:56,760
+من 360 أكثر من 360 أكثر من 360 أكثر من 360 أكثر من
+
+433
+00:34:56,760 --> 00:34:57,420
+360 أكثر من 360 أكثر من 360 أكثر من 360 أكثر من
+
+434
+00:34:57,420 --> 00:35:04,520
+360 أكثر من 360
+
+435
+00:35:06,640 --> 00:35:09,900
+النسبة للمعرفة الموجودة في المعرفة الموجودة في
+
+436
+00:35:09,900 --> 00:35:12,620
+الموجودة في المعرفة الموجودة في المعرفة الموجودة
+
+437
+00:35:12,620 --> 00:35:17,960
+في المعرفة الموجودة في المعرفة الموجودة في المعرفة
+
+438
+00:35:17,960 --> 00:35:18,760
+الموجودة في المعرفة الموجودة في المعرفة الموجودة
+
+439
+00:35:18,760 --> 00:35:19,400
+الموجودة في المعرفة الموجودة في المعرفة الموجودة
+
+440
+00:35:19,400 --> 00:35:21,720
+في المعرفة الموجودة في المعرفة الموجودة في المعرفة
+
+441
+00:35:21,720 --> 00:35:27,940
+الموجودة في المعرفة الموجودة في المعرفة
+
+442
+00:35:27,940 --> 00:35:31,100
+الموجودة في المعرفة الموجودة في المعرفة الموجودة
+
+443
+00:35:31,100 --> 00:35:35,760
+في المعرف
+
+444
+00:35:36,150 --> 00:35:40,530
+طيب what is the interest rate that increase the
+
+445
+00:35:40,530 --> 00:35:45,270
+equilibrium output to what؟ 800 يعني اللي هو الـ Y2
+
+446
+00:35:45,270 --> 00:35:52,330
+exactly Y2 equals 800 هلا بدي أطلع قيمة الـ R1 عشان
+
+447
+00:35:52,330 --> 00:35:58,430
+أشتغل على الـ I1 مظبوط so قديش الـ I1 نرجع للـ table
+
+448
+00:35:58,430 --> 00:36:02,930
+هان عشان تسعة احنا قاعدين في جوالات
+
+449
+00:36:18,900 --> 00:36:31,570
+Y2-Y1-Y2-Y2-Y2-Y2-Y2-Y2-Y2-320 اعمل تعويض بيصير ان
+
+450
+00:36:31,570 --> 00:36:37,430
+الـ I2 equals قداش مش عارف قداش الـ answer قداش الـ
+
+451
+00:36:37,430 --> 00:36:43,490
+I2 نفس الطريقة يعني هذا 200 على شغل رياضيات بنجيب
+
+452
+00:36:43,490 --> 00:36:47,090
+الـ I2 بتطلع عليها رقم و بنشوف الـ R اللي تقابلها
+
+453
+00:36:51,110 --> 00:36:55,130
+اللي هو الإجابة ميعطينيها هيك answer is C بيكون ست
+
+454
+00:36:55,130 --> 00:36:59,070
+.. six hundred six percent قداش بيكون الـ .. الـ ..
+
+455
+00:36:59,070 --> 00:37:03,550
+الـ planned investment لو بنجي نعمله حسبة بيكون
+
+456
+00:37:03,550 --> 00:37:06,410
+three hundred and sixty هذا الـ planned investment
+
+457
+00:37:06,410 --> 00:37:14,630
+number two تمام؟ طيب let's go to this exam or
+
+458
+00:37:14,630 --> 00:37:18,510
+exercise I don't know we have to analyze
+
+459
+00:37:23,230 --> 00:37:27,610
+multiplier equals 10 the initial interest rate is
+
+460
+00:37:27,610 --> 00:37:35,550
+15 R1 equals 15% وبالتالي قداش الـ I1 بنشوف فهي قداش
+
+461
+00:37:35,550 --> 00:37:39,250
+رقمها طيب what would be the impact on the
+
+462
+00:37:39,250 --> 00:37:44,570
+equilibrium output if the interest rate fell to 6%
+
+463
+00:37:44,570 --> 00:37:53,670
+الـ R2 6%قداش بده الـ change في الـ aggregate output
+
+464
+00:37:53,670 --> 00:38:02,190
+خلينا نرجع للـ table هان R2 R1 عند 15 قداش الـ .. الـ
+
+465
+00:38:02,190 --> 00:38:09,530
+.. الـ .. الـ planned investment 240 و I2 مقابل الـ 6
+
+466
+00:38:09,530 --> 00:38:19,150
+360 شلون ده؟عقله صحيح ten equals delta y over i
+
+467
+00:38:19,150 --> 00:38:22,450
+two minus i one three hundred sixty minus four
+
+468
+00:38:22,450 --> 00:38:31,290
+hundred two hundred forty ten هي ten مش five ten
+
+469
+00:38:31,290 --> 00:38:38,170
+times قداش الفرق ما بينه one hundred twenty equals
+
+470
+00:38:38,170 --> 00:38:43,450
+delta y so delta y equals one thousand two hundred
+
+471
+00:38:43,450 --> 00:38:44,170
+that's it
+
+472
+00:38:52,410 --> 00:38:57,670
+هيو it would increase by one thousand two hundred
+
+473
+00:38:57,670 --> 00:39:04,990
+billion طيب when the income increases the money
+
+474
+00:39:04,990 --> 00:39:10,850
+demand curve shifts to لوين؟ right exactly which
+
+475
+00:39:10,850 --> 00:39:16,050
+space the intersect with a fixed money supply
+
+476
+00:39:16,050 --> 00:39:19,050
+خليني نعمل رسمة نشوف شو الوضع أو التحليل
+
+477
+00:39:29,300 --> 00:39:32,520
+السؤال بيقول when the income increased خليني أعمل
+
+478
+00:39:32,520 --> 00:39:35,840
+increasing في الـ income شو بيعمل increasing ل
+
+479
+00:39:35,840 --> 00:39:42,380
+money demand increasing R which increase the
+
+480
+00:39:42,380 --> 00:39:45,540
+interest rate of the fixed money supply إذن هذا
+
+481
+00:39:45,540 --> 00:39:49,940
+هيروح على وين الـ right money demand curve هيروح لل
+
+482
+00:39:49,940 --> 00:39:56,130
+right و الـ interest rate would increase صح؟ طيب
+
+483
+00:39:56,130 --> 00:40:00,650
+fiscal policy affects the goods marketed through
+
+484
+00:40:00,650 --> 00:40:04,650
+what؟ الـ fiscal policy بيأثر في الـ goods market في
+
+485
+00:40:04,650 --> 00:40:06,490
+إيش؟ ضرائب، ضرائب، ضرائب، ضرائب، ضرائب، ضرائب،
+
+486
+00:40:06,490 --> 00:40:07,570
+ضرائب، ضرائب، ضرائب، ضرائب، ضرائب، ضرائب، ضرائب،
+
+487
+00:40:07,570 --> 00:40:09,490
+ضرائب، ضرائب، ضرائب، ضرائب، ضرائب، ضرائب، ضرائب،
+
+488
+00:40:09,490 --> 00:40:15,530
+ضرائب، ضرائب، ضرائب،
+
+489
+00:40:15,530 --> 00:40:16,970
+ضرا
+
+490
+00:40:20,140 --> 00:40:24,400
+الـ income و الـ money demand، بصبوح؟ هذا الـ fiscal
+
+491
+00:40:24,400 --> 00:40:27,780
+policy بيأثر على الـ income و بعدين على الـ money
+
+492
+00:40:27,780 --> 00:40:33,060
+demand، مش هي تأثيره على الـ money market، صح؟ طيب
+
+493
+00:40:33,060 --> 00:40:38,380
+الـ monetary policy affects the goods market Through
+
+494
+00:40:38,380 --> 00:40:41,840
+its effects on what؟ تأثيره على الـ interest rate
+
+495
+00:40:41,840 --> 00:40:44,220
+وعلى الـ planned investment بصبوح؟ مش هي الـ
+
+496
+00:40:44,220 --> 00:40:46,620
+monetary policy تأثيره على الـ interest rate و
+
+497
+00:40:46,620 --> 00:40:48,700
+بعدين على الـ planned investment ومتأثر على الـ
+
+498
+00:40:48,700 --> 00:40:52,100
+aggregate expenditure صح؟ يعني لو بدنا نشتغل هيك
+
+499
+00:40:52,100 --> 00:40:55,160
+تأثير الـ monetary policy increasing في الـ R leads
+
+500
+00:40:55,160 --> 00:40:57,880
+to a decreasing in I decreasing aggregate
+
+501
+00:40:57,880 --> 00:41:01,600
+expenditure و بعدها decreasing Y فالتأثير الـ
+
+502
+00:41:01,600 --> 00:41:05,440
+monetary policy على الـ goods market من خلال الـ
+
+503
+00:41:05,440 --> 00:41:09,440
+interest rate و الـ planned investment طيب خليني
+
+504
+00:41:09,440 --> 00:41:15,540
+أشوف هذا هم
+
+505
+00:41:15,540 --> 00:41:19,180
+يعطيني relationship between the interest rate و الـ
+
+506
+00:41:19,180 --> 00:41:20,940
+planned investment و هذا الـ planned investment
+
+507
+00:41:20,940 --> 00:41:24,700
+curve refer to the figure the planned investment
+
+508
+00:41:24,700 --> 00:41:29,660
+could decrease from 12 million to 8 million يعني
+
+509
+00:41:29,660 --> 00:41:34,460
+شو اللي بيخلي الـ planned investment ينزل من 12 ل 8
+
+510
+00:41:36,620 --> 00:41:42,200
+من 12 ل 8 decreasing في الـ investment شو معناها ده
+
+511
+00:41:42,200 --> 00:41:46,160
+أنه في عندي increasing في الـ interest rate from 6
+
+512
+00:41:46,160 --> 00:41:51,520
+to 10 تمام بس بدي أرجع للسؤال شوف شو رضيع بيعطينا
+
+513
+00:41:51,520 --> 00:41:54,740
+الإجابات if the government increase the government
+
+514
+00:41:54,740 --> 00:42:00,740
+purchases لو زودنا هذا التحليل مختلف لو زودنا الـ
+
+515
+00:42:00,740 --> 00:42:06,080
+government purchases يعني اللي هو increasing G ماذا
+
+516
+00:42:06,080 --> 00:42:08,600
+بتعمل؟ increasing aggregate expenditure,
+
+517
+00:42:08,920 --> 00:42:13,760
+increasing Y, increasing money demand, increasing
+
+518
+00:42:13,760 --> 00:42:18,460
+R, decreasing I اذا شو اللي خلّى في عندي
+
+519
+00:42:18,460 --> 00:42:21,660
+decreasing في الـ I هو اللي increasing في الـ R أو
+
+520
+00:42:21,660 --> 00:42:28,660
+اللي هو زيادة الـ government purchases مظبوط؟ احنا
+
+521
+00:42:28,660 --> 00:42:33,160
+بنصل للـ R بستمام اه هو السؤال انه ليش صار في عنده
+
+522
+00:42:33,160 --> 00:42:36,200
+decreasing في الـ planned investment لأنه الـ
+
+523
+00:42:36,200 --> 00:42:40,640
+government purchases increased لو جربنا التاني انه
+
+524
+00:42:40,640 --> 00:42:45,230
+الـ federal increased money supply يعني لجرب الـ P
+
+525
+00:42:45,230 --> 00:42:48,430
+نشوف شو الوضع صح ولا غلط if the federal increase
+
+526
+00:42:48,430 --> 00:42:51,310
+the money supply نشوف الوضع صح ولا غلط increasing
+
+527
+00:42:51,310 --> 00:42:55,290
+في الـ money supply شو بيعمل decrease R increase I
+
+528
+00:42:55,290 --> 00:42:57,990
+هو السؤال بيقولك بيقول cash increase في الـ I بيديه
+
+529
+00:42:57,990 --> 00:43:02,290
+decreasing في الـ I شو السبب؟ اذا الإجابة wrong،
+
+530
+00:43:02,290 --> 00:43:06,430
+صحيح؟ طيب المرة اللي جاي ان شاء الله بنكمل يعطيكم
+
+531
+00:43:06,430 --> 00:43:06,790
+العافية
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/PziFuZwogc8.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/PziFuZwogc8.srt
new file mode 100644
index 0000000000000000000000000000000000000000..313305725afdf2460f1dbcff4cc9c7f37dc73593
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/PziFuZwogc8.srt
@@ -0,0 +1,2320 @@
+1
+00:00:20,990 --> 00:00:24,430
+Okay, بسم الله الرحمن الرحيم، اليوم إن شاء الله سوف 
+
+2
+00:00:24,430 --> 00:00:30,130
+نكمل التدريبات الواقعية على الفصل 8، أعتقد أن في 
+
+3
+00:00:30,130 --> 00:00:33,150
+السلسلة الأخيرة التي وصلنا إلى هذه النقطة، كما ترى
+
+4
+00:00:33,150 --> 00:00:37,110
+هذا هو مقارنة الاستثمار أو مقارنة الاستثمار المخطط 
+
+5
+00:00:37,110 --> 00:00:43,210
+الذي يظهر علاقة خاطئة بين قيمة الدفع والاستثمار 
+
+6
+00:00:43,210 --> 00:00:49,720
+المخطط. دعونا نذهب إلى التدريبات، بالنسبة للنسبة 12.4
+
+7
+00:00:49,720 --> 00:00:55,280
+مليون دولار، يمكن أن تتقلص من 12 مليون دولار إلى 8
+
+8
+00:00:55,280 --> 00:01:00,420
+مليون دولار إذا كان هناك انخفاض من 12 مليون دولار إلى
+
+9
+00:01:00,420 --> 00:01:01,920
+8 مليون دولار، إذا كان هناك انخفاض من 12 مليون دولار
+
+10
+00:01:01,920 --> 00:01:03,360
+إذا كان هناك انخفاض من 12 مليون دولار، إذا كان هناك
+
+11
+00:01:03,360 --> 00:01:04,540
+انخفاض من 12 مليون دولار، إذا كان هناك انخفاض من 12 مليون
+
+12
+00:01:04,540 --> 00:01:04,700
+دولار، إذا كان هناك انخفاض من 12 مليون دولار، إذا كان
+
+13
+00:01:04,700 --> 00:01:04,980
+مليون دولار، إذا كان هناك انخفاض من 12 مليون دولار، إذا
+
+14
+00:01:04,980 --> 00:01:06,620
+كان هناك انخفاض من 12 مليون دولار، إذا كان هناك انخفاض من
+
+15
+00:01:06,620 --> 00:01:10,820
+12 مليون دولار. هنا لدينا إجابة نتعامل معها، لذا دعونا 
+
+16
+00:01:10,820 --> 00:01:16,420
+نجرب ونرى أيه هي الإجابة المناسبة، رقم واحد، أو أيه 
+
+17
+00:01:16,420 --> 00:01:20,740
+إذا كان الحكومة تزيد إنفاق الحكومة، لذا دعونا 
+
+18
+00:01:20,740 --> 00:01:23,580
+نعتمد على أن الحكومة تزيد إنفاقها أو إنفاق
+
+19
+00:01:23,580 --> 00:01:29,120
+الحكومة، هذا يعني ماذا؟ تزيد الإنفاق العام، الإنفاق 
+
+20
+00:01:29,120 --> 00:01:31,280
+العام، الإنفاق العام، الإنفاق العام
+
+21
+00:01:36,070 --> 00:01:42,210
+Increasing Y, Money Demand, Increasing R, Decreasing
+
+22
+00:01:42,210 --> 00:01:48,070
+I. This is the correct answer. حلّيناها ده، حلّيناها ده
+
+23
+00:01:48,070 --> 00:01:51,430
+حلّيناها ده، حلّيناها ده، حلّيناها ده، حلّيناها ده، حلّيناها ده
+
+24
+00:01:51,430 --> 00:01:51,510
+حلّيناها ده، حلّيناها ده، حلّيناها ده، حلّيناها ده، حلّيناها ده
+
+25
+00:01:51,510 --> 00:01:55,530
+حلّيناها ده، حلّيناها ده، حلّيناها ده، حلّيناها ده، حلّيناها ده
+
+26
+00:01:55,530 --> 00:02:02,150
+حلّيناها ده، حلّيناها ده، ح
+
+27
+00:02:03,710 --> 00:02:06,910
+الجمهور يجب أن يجرب ماذا؟ يجب أن يجرب C
+
+28
+00:02:16,790 --> 00:02:21,930
+وهو نفس الأفعال لإزالة إنفاق الحكومة، وهذا يؤدي إلى
+
+29
+00:02:21,930 --> 00:02:27,330
+إزالة إنفاق المجموعات، إزالة Y، إزالة أسعار المال، 
+
+30
+00:02:27,330 --> 00:02:33,630
+إزالة R، إزالة I، لذلك يمكن أن تدخل أو تتخلص 
+
+31
+00:02:33,630 --> 00:02:38,580
+الاستثمار المشروع، إذا كان الحكومة تنقل أو تقوم
+
+32
+00:02:38,580 --> 00:02:42,000
+بتقليص حجم المال من التداول؟ دعونا نعتمد على حالة
+
+33
+00:02:42,000 --> 00:02:49,220
+عكسية، إذا كانت المعدلات التخزينية تنقل من 12%
+
+34
+00:02:49,220 --> 00:02:56,100
+إلى 16%؟ تنقل، تنقل، تنقل
+
+35
+00:03:26,480 --> 00:03:31,300
+ماذا هو الإجابة الأفضل هنا؟ Bones in the open
+
+36
+00:03:31,300 --> 00:03:35,160
+market. فلنجرب أن نرى Buying Bones, Buying Bones
+
+37
+00:03:35,160 --> 00:03:39,460
+ماذا يفعل في الـ money supply exactly, so the second
+
+38
+00:03:39,460 --> 00:03:46,960
+اللي هو الـ B، Buying Bones، increasing
+
+39
+00:03:46,960 --> 00:03:53,170
+money supply, decreasing R, increasing I، كمان هذه it 
+
+40
+00:03:53,170 --> 00:03:56,970
+should be correct. لو بدي أفترض أنه في عندي
+
+41
+00:03:56,970 --> 00:04:00,890
+analysis معين، مظبوط ولا لأ؟ طيب، let's say another
+
+42
+00:04:00,890 --> 00:04:07,730
+the planned investment decreased or could decrease
+
+43
+00:04:07,730 --> 00:04:12,130
+from 12 to 8 million dollars if، طبعا أن الـ answer
+
+44
+00:04:12,130 --> 00:04:14,750
+B، خلينا نجرب أنه increase in government purchases 
+
+45
+00:04:14,750 --> 00:04:20,710
+شفنا the same, yes. طيب عندنا decreasing في الـ plan
+
+46
+00:04:20,710 --> 00:04:25,130
+investment from 16 million to 12 million، F، the
+
+47
+00:04:25,130 --> 00:04:28,130
+federal sell bonds. خليني أشوف لو نعمل selling the
+
+48
+00:04:28,130 --> 00:04:35,790
+bonds، selling bonds، bonds، decreasing the money 
+
+49
+00:04:35,790 --> 00:04:40,890
+supply، increase R، decrease I، so it should be the
+
+50
+00:04:40,890 --> 00:04:41,630
+correct answer.
+
+51
+00:04:44,870 --> 00:04:48,050
+هلا في عندي increasing بيه الـ planned investment 
+
+52
+00:04:48,050 --> 00:04:53,930
+from eight to twelve million dollars if. جربونا و
+
+53
+00:04:53,930 --> 00:04:58,450
+اعطينا الـ answers  دين، نشوف مظبوط ولا مش مظبوط the
+
+54
+00:04:58,450 --> 00:05:01,530
+federal lowers the discount rate. So, suppose there
+
+55
+00:05:01,530 --> 00:05:06,430
+is a decreasing in the discount rate. This leads to 
+
+56
+00:05:06,430 --> 00:05:10,750
+increase in money supply, decrease R, increase I.
+
+57
+00:05:10,750 --> 00:05:15,590
+So, it should be correct. طب لو جربنا شيء ثاني for
+
+58
+00:05:15,590 --> 00:05:21,210
+the first case or the second case شيء جديد، ده
+
+59
+00:05:21,210 --> 00:05:26,980
+بيخد أي case بيلاقي مش مطابق، لا ينطبق. طيب، which
+
+60
+00:05:26,980 --> 00:05:30,940
+of the following sequence of events follows an 
+
+61
+00:05:30,940 --> 00:05:33,480
+expansionary monetary policy؟ هذا السؤال جاء في 
+
+62
+00:05:33,480 --> 00:05:37,960
+الامتحان بالـ multiple choice العام الماضي زي هيك و
+
+63
+00:05:37,960 --> 00:05:41,880
+خلّيني أخد different cases عليه. السؤال إيش بيقول؟ 
+
+64
+00:05:41,880 --> 00:05:47,940
+أنّ expansionary monetary policy، أنّه فيهم يتبع لـ 
+
+65
+00:05:47,940 --> 00:05:50,920
+expansionary monetary policy. Expansionary monetary 
+
+66
+00:05:50,920 --> 00:05:56,580
+policy means the increasing money supply. Decrease
+
+67
+00:05:56,580 --> 00:06:02,120
+R, Increase I, Increase Aggregate Expenditure,
+
+68
+00:06:02,580 --> 00:06:07,420
+Increase Y. So which is the correct answer? C,
+
+69
+00:06:08,080 --> 00:06:12,900
+Decrease R, Increase I, Increase Aggregate 
+
+70
+00:06:12,900 --> 00:06:18,440
+Expenditure, Increase Y. طب جرب A, A, Increase R 
+
+71
+00:06:18,440 --> 00:06:23,240
+وابتدالي هذا مش مظبوط. الـ contraction. طب جرب دي، دي
+
+72
+00:06:23,240 --> 00:06:26,860
+is a contraction. But let us follow the procedures 
+
+73
+00:06:26,860 --> 00:06:32,300
+decreasing R, decreasing I. So, it's not correct، لأنّه 
+
+74
+00:06:32,300 --> 00:06:35,640
+decreasing in R leads to increasing in I, right?
+
+75
+00:06:35,640 --> 00:06:40,340
+Okay, what 
+
+76
+00:06:40,340 --> 00:06:41,540
+else? Yes.
+
+77
+00:06:51,110 --> 00:06:55,350
+هذا لـ crowding out، if you remember. هذا في المرحلة
+
+78
+00:06:55,350 --> 00:06:57,870
+الثانية، تمام. هيو.
+
+79
+00:07:04,880 --> 00:07:09,660
+بصراحة بس you have to follow the process، بتأكّد تتبع
+
+80
+00:07:09,660 --> 00:07:13,720
+العملية كلّها من البداية. الـ expansion of monetary 
+
+81
+00:07:13,720 --> 00:07:16,340
+policy means أنّه increase in the supply، وبالتالي
+
+82
+00:07:16,340 --> 00:07:18,920
+ماذا الـ effects على الـ interest rate و الـ planned
+
+83
+00:07:18,920 --> 00:07:21,620
+investment، the aggregate expenditure and so on,
+
+84
+00:07:21,620 --> 00:07:25,900
+right? Which
+
+85
+00:07:25,900 --> 00:07:29,500
+is، which of the following sequence of events
+
+86
+00:07:29,500 --> 00:07:35,950
+follows a rise in the discount rate، rise الـ discount 
+
+87
+00:07:35,950 --> 00:07:44,390
+rate. Decrease الوضع المالي، Decrease R، Decrease I، Decrease
+
+88
+00:07:44,390 --> 00:07:49,510
+aggregate expenditure، Decrease Y. إذا أين هي السلسلة 
+
+89
+00:07:49,510 --> 00:07:54,430
+الصحيحة؟ السلسلة الصحيحة بيه، لأنّ هناك زيادة في R، 
+
+90
+00:07:54,430 --> 00:08:00,290
+Decrease I، Decrease aggregate expenditure، Decrease Y. صعب
+
+91
+00:08:00,290 --> 00:08:02,130
+لو في شيء زي هيك في الامتحان؟
+
+92
+00:08:05,640 --> 00:08:08,660
+طيب، which of the following sequence of events
+
+93
+00:08:08,660 --> 00:08:11,500
+follows an expansion fiscal policy؟ Expansion 
+
+94
+00:08:11,500 --> 00:08:14,020
+fiscal policy means increasing the government
+
+95
+00:08:14,020 --> 00:08:17,360
+spending or decreasing the taxes، صح؟ So,
+
+96
+00:08:17,880 --> 00:08:20,700
+increasing the government spending or decreasing 
+
+97
+00:08:20,700 --> 00:08:24,060
+taxes، this leads to increasing aggregate
+
+98
+00:08:24,060 --> 00:08:27,920
+expenditure، increase Y، increase money demand،
+
+99
+00:08:28,980 --> 00:08:31,480
+increase R، decrease I. 
+
+100
+00:08:34,550 --> 00:08:38,470
+كمان أنّه decrease في الـ aggregate expenditure، هذا 
+
+101
+00:08:38,470 --> 00:08:42,670
+اللي هو الموضوع الـ crowding out، صح؟ طيب، إذا which is
+
+102
+00:08:42,670 --> 00:08:46,490
+the best answer؟ B، because increasing aggregate
+
+103
+00:08:46,490 --> 00:08:51,430
+expenditure هي increase Y، increase money demand، R
+
+104
+00:08:51,430 --> 00:08:57,030
+decrease، and so on. صعبين؟ طيب، which of the 
+
+105
+00:08:57,030 --> 00:09:01,390
+following sequence of events follows an increase
+
+106
+00:09:01,390 --> 00:09:02,730
+in the net taxes؟ 
+
+107
+00:09:04,960 --> 00:09:09,100
+التعافي المالي يعني أنّه في نفس الاتجاه، في نفس
+
+108
+00:09:09,100 --> 00:09:13,100
+الاحتياطات التي تتخلص من الإنفاق الحكومي، فهذا
+
+109
+00:09:13,100 --> 00:09:14,700
+يعني تخلص من الإنفاق الحكومي، التي تتخلص من
+
+110
+00:09:14,700 --> 00:09:18,920
+الإنفاق الحكومي، التي تتخلص من الإنفاق
+
+111
+00:09:18,920 --> 00:09:24,170
+الحكومي. Decrease R, Increase I, Increase Aggregate
+
+112
+00:09:24,170 --> 00:09:28,570
+Expenditure. So, which is the correct answer? D. 
+
+113
+00:09:29,530 --> 00:09:32,450
+Decreasing aggregate expenditure, decrease Y,
+
+114
+00:09:32,590 --> 00:09:38,950
+decrease money demand and so on، صح؟ If the planned
+
+115
+00:09:38,950 --> 00:09:43,850
+investment does not fall when the interest rate 
+
+116
+00:09:43,850 --> 00:09:44,490
+rises, 
+
+117
+00:09:47,600 --> 00:09:52,680
+this means أنّه ما فيش sensitive أو الـ investment is
+
+118
+00:09:52,680 --> 00:09:58,320
+ما له مش حساس لسعر الفائدة، the interest rate، مظبوط؟ 
+
+119
+00:09:58,320 --> 00:10:00,420
+هلا، السؤال بيقول أنّه if the planned investment
+
+120
+00:10:00,420 --> 00:10:04,820
+does not fall when the interest rate rises، يعني مع
+
+121
+00:10:04,820 --> 00:10:09,420
+الكلام أنّه هيكون vertical line exactly، so this is 
+
+122
+00:10:09,420 --> 00:10:14,790
+the planned investment curve. R، I. السؤال بيقول أنّه 
+
+123
+00:10:14,790 --> 00:10:18,290
+لما الـ interest rate ارتفع، ما ينزلش الـ interest ..
+
+124
+00:10:18,290 --> 00:10:20,690
+الـ .. الـ planned investment أو الـ investment. So، 
+
+125
+00:10:20,690 --> 00:10:25,730
+suppose this is a, b, and increasing in the .. the
+
+126
+00:10:25,730 --> 00:10:30,770
+interest rate would not change or has no effect on
+
+127
+00:10:30,770 --> 00:10:33,470
+the planned investment. So, in this case the planned
+
+128
+00:10:33,470 --> 00:10:36,390
+investment curve is what؟ Is a vertical line؟ The 
+
+129
+00:10:36,390 --> 00:10:40,210
+crowding out is what؟ Zero equals zero، مظبوط؟ The 
+
+130
+00:10:40,210 --> 00:10:45,830
+crowding out effect is zero. طب لو أنا مخطط أنّه ازود
+
+131
+00:10:45,830 --> 00:10:49,690
+الناتج بـ 200 أو بـ 400، بزيد بنفس النتيجة بنفس الـ .. 
+
+132
+00:10:49,690 --> 00:10:55,390
+the same plan، مظبوط أو لا؟ طيب، so in this case no
+
+133
+00:10:55,390 --> 00:10:59,590
+crowding out effect، مش هيرجع الناتج يرجع .. ينزل 
+
+134
+00:10:59,590 --> 00:11:04,910
+مرة ثانية. طيب، the steeper the planned investment 
+
+135
+00:11:04,910 --> 00:11:09,150
+schedule curve، إيش ما له هذا؟ Steeper means يعني الـ
+
+136
+00:11:09,150 --> 00:11:13,180
+.. الـ .. رايح باتجاه العمودي، الأكثر عموديا .. 
+
+137
+00:11:13,180 --> 00:11:19,740
+الميل، الأكثر ميلًا، الميل قريب العمودي، هذا إيش 
+
+138
+00:11:19,740 --> 00:11:22,880
+ميله؟ اللي هو الـ answer would be the smaller is
+
+139
+00:11:22,880 --> 00:11:26,080
+the crowding out effect. The stable means أنّه يعني
+
+140
+00:11:26,080 --> 00:11:31,080
+كلّ ما كان قريب من العمودي زي هيك أو قريب من هيك 
+
+141
+00:11:31,080 --> 00:11:36,920
+يعني يكون في عنده the smaller crowding out effect طب لو
+
+142
+00:11:36,920 --> 00:11:40,040
+كان flatter .. flatter means قريب من ال .. ال
+
+143
+00:11:40,040 --> 00:11:43,900
+horizontal lineبيكون في عندي high sensitivity
+
+144
+00:11:43,900 --> 00:11:48,900
+between the investment and the interest rate هايو
+
+145
+00:11:48,900 --> 00:11:52,940
+the flatter the planned investment curve اللي هو
+
+146
+00:11:52,940 --> 00:11:56,400
+هيكون ايش ماله؟ the larger crowding out effect
+
+147
+00:11:56,400 --> 00:11:59,620
+بظبط؟ or the greater crowding out effect؟ مين مش
+
+148
+00:11:59,620 --> 00:12:02,840
+رايه بالنقطة هاي؟ نفس التحلي اللي بنشتغل عليها ال
+
+149
+00:12:02,840 --> 00:12:09,860
+gate هذا طيبThere will be no crowding out effect when
+
+150
+00:12:09,860 --> 00:12:12,480
+the government increases spending and the planned
+
+151
+00:12:12,480 --> 00:12:16,820
+investment and the planned investment curve is
+
+152
+00:12:16,820 --> 00:12:22,280
+a vertical line. Yes. Assume
+
+153
+00:12:22,280 --> 00:12:25,980
+that the investment spending depends on the
+
+154
+00:12:25,980 --> 00:12:28,520
+interest rate. يعني there is a relationship between
+
+155
+00:12:28,520 --> 00:12:30,940
+the interest rate and the investment. يعني جاي عادي هيك
+
+156
+00:12:30,940 --> 00:12:33,420
+the curve جاي هيك
+
+157
+00:12:39,850 --> 00:12:43,990
+assume that the investment spending depends on the
+
+158
+00:12:43,990 --> 00:12:47,470
+interest rate as the supply of money is increased.
+
+159
+00:12:53,090 --> 00:12:58,310
+هذا يعني أنه يتخلص من R يتخلص من I تمام، شوف شو
+
+160
+00:12:58,310 --> 00:13:03,610
+الوضع الـ interest rate طبعا ماله تتخلص و ال
+
+161
+00:13:03,610 --> 00:13:10,690
+investment plan يتخلص طيب، إذا كتابة الinvestment
+
+162
+00:13:10,690 --> 00:13:13,130
+demand كتابة كتابة كتابة كتابة كتابة كتابة كتابة
+
+163
+00:13:13,130 --> 00:13:20,550
+كتابة كتابة كتابة كتابة كتابة كتابة كتابة كتابة
+
+164
+00:13:20,550 --> 00:13:20,710
+كتابة كتابة كتابة كتابة كتابة كتابة كتابة كتابة
+
+165
+00:13:20,710 --> 00:13:23,890
+كتابة كتابة كتابة كتابة كتابة كتابة كتابة كتلا مش
+
+166
+00:13:23,890 --> 00:13:29,390
+صح in this case the efficient crowding out effect
+
+167
+00:13:29,390 --> 00:13:32,110
+مظبوط؟ مش هيرجع النتج يعني لو سببز انه انا عملت
+
+168
+00:13:32,110 --> 00:13:36,070
+increasing في ال government spending هيزيد النتج
+
+169
+00:13:36,070 --> 00:13:40,430
+بنفس المعنى المخطط مش هيرجع النتج ينزل وبالتالي in
+
+170
+00:13:40,430 --> 00:13:43,850
+this case the fiscal policy would be effective بس
+
+171
+00:13:43,850 --> 00:13:47,390
+ال .. ال .. ال .. ال monetary policy is ineffective بالمرة
+
+172
+00:13:47,390 --> 00:13:50,570
+مظبوط؟ تفكرين و هذا شرحناه المرة اللي فاتت و احنا
+
+173
+00:13:50,570 --> 00:13:55,920
+بنرجع نعمل review على ال ..شباب إذا كان if the
+
+174
+00:13:55,920 --> 00:13:59,680
+planned investment is a vertical line تمام مافيش
+
+175
+00:13:59,680 --> 00:14:02,500
+crowding out يعني مش هيرجع النتيجة في مرحلة تانية
+
+176
+00:14:02,500 --> 00:14:07,040
+ينزل وبالتالي إذا أنا مخطط أن أزيد النتيجة بكذا
+
+177
+00:14:07,040 --> 00:14:12,400
+هيزيد بنفس المقدار اللي أنا مخطط فيه وبالتالي ال
+
+178
+00:14:12,400 --> 00:14:15,680
+fiscal policy is effective و ال monetary
+
+179
+00:14:15,680 --> 00:14:18,380
+policy is ineffective بدا أرجع للنقطة هاي عشان و كأنهش أحس
+
+180
+00:14:18,380 --> 00:14:18,980
+في إيش ambiguous
+
+181
+00:14:24,170 --> 00:14:28,710
+Suppose we use an expansionary fiscal policy استخدمنا
+
+182
+00:14:28,710 --> 00:14:34,450
+سياسة مالية توسعية Increasing G leads to what?
+
+183
+00:14:34,510 --> 00:14:37,610
+Increasing aggregate expenditure. Increase Y.
+
+184
+00:14:37,610 --> 00:14:45,250
+Increase money demand. Increase R. Decrease I. مش هيك
+
+185
+00:14:45,250 --> 00:14:51,770
+الوضع؟aggregate expenditure increases. Y with a
+
+186
+00:14:51,770 --> 00:14:59,790
+small increase. Small small small if the investment
+
+187
+00:14:59,790 --> 00:15:03,550
+curve is a vertical line was a vertical line معناه
+
+188
+00:15:03,550 --> 00:15:06,930
+الكلمة انه اي زيادة في ال interest rate مش هيأثر
+
+189
+00:15:06,930 --> 00:15:10,250
+على ال investment وابتدا مش هينزل اذا ال monetary
+
+190
+00:15:10,250 --> 00:15:14,170
+policy ما لها it's not effective or ineffective بس
+
+191
+00:15:14,170 --> 00:15:16,950
+من اللي صار effective الفيسكال policy لأنه انا
+
+192
+00:15:16,950 --> 00:15:19,550
+زودت ال government spending زاد الناتج زي ما بدي
+
+193
+00:15:19,550 --> 00:15:28,730
+that's it صح؟ طيب let's go to this figure as you
+
+194
+00:15:28,730 --> 00:15:34,170
+see we have aggregate expenditure 0 1 2
+
+195
+00:15:34,170 --> 00:15:38,730
+كدهش
+
+196
+00:15:38,730 --> 00:15:42,150
+ال slope تبع ال function هذا او ال marginal
+
+197
+00:15:42,150 --> 00:15:49,670
+propensity to consume MPC فاكرين كيف نعمل ال MPC تمام
+
+198
+00:15:49,670 --> 00:15:54,590
+خد triangle هيك و اعمل احسب لل marginal
+
+199
+00:15:54,590 --> 00:15:57,670
+propensity to consume اللي هو هذا المسافة على هجم
+
+200
+00:15:57,670 --> 00:16:03,530
+200 minus 100 exactly تمام ال MPC marginal
+
+201
+00:16:03,530 --> 00:16:10,070
+propensity to consume equals 200 minus 100 over 200
+
+202
+00:16:10,070 --> 00:16:20,830
+minus 100 over 200 equals 0.5 that's it how much
+
+203
+00:16:20,830 --> 00:16:24,190
+is the multiplier the government spending
+
+204
+00:16:24,190 --> 00:16:29,550
+multiplier الgovernment spending multiplier 1
+
+205
+00:16:29,550 --> 00:16:36,670
+over MPS equals 1 over 1 minus MPC 0.5 equals
+
+206
+00:16:36,670 --> 00:16:41,960
+2. قال له هذا السؤال هيك what is the multiplier in
+
+207
+00:16:41,960 --> 00:16:48,900
+this economy تمام خلاص تو yes طيب how much is the
+
+208
+00:16:48,900 --> 00:16:58,220
+tax multiplier خليني أحكي في tax multiplier minus
+
+209
+00:16:58,220 --> 00:17:06,480
+MPC over MPS minus 0.5 over 1 minus 0.5 sorry over
+
+210
+00:17:06,480 --> 00:17:14,130
+positive 0.5 minus 1 صح؟ مظبوط؟ طيب جديش ال balance
+
+211
+00:17:14,130 --> 00:17:20,390
+budget multiplier؟ 1 yes لأنه ال government
+
+212
+00:17:20,390 --> 00:17:23,890
+spending multiplier plus the tax multiplier 2
+
+213
+00:17:23,890 --> 00:17:32,270
+minus 1 equals 1 صح؟ مظبوط؟ طيب let's
+
+214
+00:17:32,270 --> 00:17:37,870
+go طيب refer to the figure 12.7
+
+215
+00:17:39,720 --> 00:17:51,340
+الأساسي الأساسي هي الأول
+
+216
+00:17:51,340 --> 00:17:54,380
+أساسي
+
+217
+00:17:54,380 --> 00:17:57,800
+أساسي أساسي الأساسي هي الأساسي الأساسي هي الأساسي
+
+218
+00:17:57,800 --> 00:17:58,420
+الأساسي هي الأساسي الأساسي هي الأساسي الأساسي هي
+
+219
+00:17:58,420 --> 00:17:58,500
+الأساسي الأساسي هي الأساسي الأساسي هي الأساسي
+
+220
+00:17:58,500 --> 00:17:58,720
+الأساسي هي الأساسي الأساسي هي الأساسي الأساسي هي
+
+221
+00:17:58,720 --> 00:17:58,760
+الأساسي الأساسي هي الأساسي الأساسي هي الأساسي
+
+222
+00:17:58,760 --> 00:18:02,820
+الأساسي هي الأساسي الأساسي هي الأساسي الأساسي هي
+
+223
+00:18:02,820 --> 00:18:05,160
+الأساس
+
+224
+00:18:06,070 --> 00:18:10,870
+على زيادة جي هذا بيقولنا انه سفينا increasing in G
+
+225
+00:18:10,870 --> 00:18:14,870
+by
+
+226
+00:18:14,870 --> 00:18:21,570
+one hundred million dollars قوله Delta G Delta G
+
+227
+00:18:21,570 --> 00:18:26,790
+okay. Delta G equals positive one hundred million
+
+228
+00:18:26,790 --> 00:18:30,630
+dollars or value and the aggregate expenditure
+
+229
+00:18:30,630 --> 00:18:34,090
+curve shifts to AE2 aggregate expenditure 2
+
+230
+00:18:34,090 --> 00:18:39,810
+AE2. We know for sure that
+
+231
+00:18:39,810 --> 00:18:43,410
+يعني احنا روحنا من وين من function اللي هو the
+
+232
+00:18:43,410 --> 00:18:46,690
+aggregate expenditure curve to AE2.
+
+233
+00:18:46,690 --> 00:18:55,610
+AE2. قدش كان ال Y 200 و ل new Y 400 هلا في هاي
+
+234
+00:18:55,610 --> 00:19:01,230
+الحالةفي عندى crowding out إذا بدى أعرف إنه كان في
+
+235
+00:19:01,230 --> 00:19:06,190
+عندى crowding out ولا لأ شباب بدى أجيب بدى أستخدم
+
+236
+00:19:06,190 --> 00:19:08,630
+قانون ال multiplier ال government spending
+
+237
+00:19:08,630 --> 00:19:13,010
+multiplier Delta
+
+238
+00:19:13,010 --> 00:19:17,790
+Y over Delta G تمام؟ طيب هل ال government spending
+
+239
+00:19:17,790 --> 00:19:21,410
+multiplier قد يش عنده 2 equals Delta Y over
+
+240
+00:19:21,410 --> 00:19:25,670
+Delta G 100 positive اذا Delta Y equals
+
+241
+00:19:25,670 --> 00:19:29,430
+200 يعني صار في عنده زيادة بمقدار قد يش
+
+242
+00:19:29,430 --> 00:19:35,250
+متين تمام؟ طب اه ارجع للشكل بس اذا زاد بمقدار 100
+
+243
+00:19:35,250 --> 00:19:39,830
+و تمانين فالكلام في crowding out صح؟ هلأ اما هذا
+
+244
+00:19:39,830 --> 00:19:47,860
+معناه طلع نفس الرقم شبابشايفين شو الوضع ال initial
+
+245
+00:19:47,860 --> 00:19:55,280
+Y قداش كانت 200 ال Delta Y زادت ل 400 اذا الفرق
+
+246
+00:19:55,280 --> 00:20:01,040
+قداش 200 هذا اذا انا مخطط ازود الناتج من 200 ل 400
+
+247
+00:20:01,040 --> 00:20:05,240
+و اعمليا زاد من 200 زاد بمقدار 200 اذا الكلام اذا
+
+248
+00:20:05,240 --> 00:20:09,520
+there is no crowding out effect بس لو راح زاد هيك
+
+249
+00:20:09,520 --> 00:20:16,730
+بعدين نرجع شويةوصار عندي ال Y هيك 180 بيكون في
+
+250
+00:20:16,730 --> 00:20:25,030
+عندي crowding out طبعا؟ طيب yes بيكون مش مخطط لأ
+
+251
+00:20:25,030 --> 00:20:29,410
+بيكون أنا مخطط أزوده هنا باللأ ل 400 بس ما زادش ال
+
+252
+00:20:29,410 --> 00:20:38,570
+400 زاد ل 380 صح؟ يعني سببز أن هذا هيك 380؟ طيب طب
+
+253
+00:20:38,570 --> 00:20:40,490
+سببز أن الوضع ماكانش هيك
+
+254
+00:20:50,370 --> 00:20:54,790
+مظبوط صحيح هي الصح اه هو هي in this case there is
+
+255
+00:20:54,790 --> 00:21:01,270
+no crowding out effect طيب suppose the initial يعني
+
+256
+00:21:01,270 --> 00:21:04,530
+الوضع كان مختلف the initial or the original point
+
+257
+00:21:04,530 --> 00:21:10,630
+was at E1 here وهذا ال aggregate expenditure curve
+
+258
+00:21:10,630 --> 00:21:16,340
+هي ال initial تمام؟وزدنا ال government spending
+
+259
+00:21:16,340 --> 00:21:23,780
+بمقدار 100 واللي صار انه بعد الزيادة هذه صارت ال
+
+260
+00:21:23,780 --> 00:21:26,600
+aggregate expenditure هي نفس aggregate expenditure
+
+261
+00:21:26,600 --> 00:21:34,840
+curve. شوله ده؟ مش مثل بالمرة عارف ايه شو معناه هذا؟
+
+262
+00:21:34,840 --> 00:21:38,580
+هذا this means انه راح النتج ارتفع ل aggregate
+
+263
+00:21:38,580 --> 00:21:42,000
+expenditure 1 or 2 و بعدين نزل مرة تانية لنفس
+
+264
+00:21:42,000 --> 00:21:48,240
+النقطة. So there is a full crowding out. صح؟ يعني في
+
+265
+00:21:48,240 --> 00:21:55,300
+عندي crowding out كامل. مظبوط
+
+266
+00:21:55,300 --> 00:21:58,720
+كلامك صحيح. The planned investment curve is a
+
+267
+00:21:58,720 --> 00:22:04,880
+horizontal line. Thank you. افهمته؟ So اذا هنا هذا
+
+268
+00:22:04,880 --> 00:22:08,720
+ال multiplier هذا اللي هو راح من aggregate
+
+269
+00:22:08,720 --> 00:22:12,640
+expenditure 0 ل 2 شو اللي إجا ال answer بيه اللي
+
+270
+00:22:12,640 --> 00:22:16,060
+هو the planned investment is perfectly insensitive
+
+271
+00:22:16,060 --> 00:22:19,880
+to that change in the interest rate. vertical line.
+
+272
+00:22:19,880 --> 00:22:24,220
+و أجا كلامك في السؤال اللي بعده انه شو قالوا ال
+
+273
+00:22:24,220 --> 00:22:27,700
+planned investment is perfectly sensitive to that
+
+274
+00:22:27,700 --> 00:22:32,990
+change. وبالتالي it should be a horizontal line. هدا وين؟ لما
+
+275
+00:22:32,990 --> 00:22:36,450
+روحنا من aggregate expenditure curve ل aggregate
+
+276
+00:22:36,450 --> 00:22:38,990
+expenditure 2 لأنه ال government عامله
+
+277
+00:22:38,990 --> 00:22:46,030
+increasing بمقدار مية full crowding out. مظبوط طيب
+
+278
+00:22:46,030 --> 00:22:56,230
+let's go to this diagram. this figure. Suppose
+
+279
+00:22:56,230 --> 00:23:00,670
+this is the original. هدا why هيك؟
+
+280
+00:23:03,980 --> 00:23:07,620
+and this is the AE1 aggregate expenditure 1. هذا اللي 
+
+281
+00:23:07,620 --> 00:23:11,820
+هو aggregate expenditure one aggregate expenditure
+
+282
+00:23:11,820 --> 00:23:18,220
+one E1 صافيًا دي decreasing في ال planned
+
+283
+00:23:18,220 --> 00:23:20,100
+investment هاي زي ما أنتم شايفين من التغير اللي
+
+284
+00:23:20,100 --> 00:23:23,760
+صار فيه في ال in the planned investment نزل مش هي
+
+285
+00:23:23,760 --> 00:23:28,220
+اللي شايفين و هيك صار طيب شو اللي خلى ال planned
+
+286
+00:23:28,220 --> 00:23:34,780
+investment ينزل هذا السؤال، ال interest rate أكيد
+
+287
+00:23:34,780 --> 00:23:38,940
+طلع، بس نتيجة إيش؟ ممكن ال money supply نزل،
+
+288
+00:23:38,940 --> 00:23:41,500
+بصبوط؟ وبالتالي قد يكون فيه مستخدمين 
+
+289
+00:23:41,500 --> 00:23:46,000
+contractionary monetary policy، بصبوط؟ هاي السؤال،
+
+290
+00:23:46,000 --> 00:23:52,020
+خدنا نروح للسؤال، السؤال بيقول إن ال interest rate
+
+291
+00:23:52,020 --> 00:23:55,000
+R1 is greater than interest rate R0
+
+292
+00:23:57,910 --> 00:24:03,310
+هيو هذا معناه أن الانتقال تبعنا C زاد plus I plus
+
+293
+00:24:03,310 --> 00:24:11,190
+G to C plus I' plus G هذا كان سببه إيش؟ A a
+
+294
+00:24:11,190 --> 00:24:13,730
+contraction of monetary policy اللي هو decreasing
+
+295
+00:24:13,730 --> 00:24:19,810
+في ال money supply وداني
+
+296
+00:24:19,810 --> 00:24:24,280
+أوين هذا؟ عملت increasing في الـR و decreasing في
+
+297
+00:24:24,280 --> 00:24:27,360
+الـI وهذا اللي أنا أصلاً بدور عليه لأنه صار فيه
+
+298
+00:24:27,360 --> 00:24:29,500
+أصلاً ال decreasing اللي صار في aggregate
+
+299
+00:24:29,500 --> 00:24:32,120
+expenditure function نتيجة أن ال planned investment
+
+300
+00:24:32,120 --> 00:24:35,980
+نزل طب لو شوف ال answer B ال contraction of fiscal
+
+301
+00:24:35,980 --> 00:24:39,960
+policy هل contraction of fiscal policy مالهاش
+
+302
+00:24:39,960 --> 00:24:46,240
+علاقة اللي هي decreasing g مثلاً leads to
+
+303
+00:24:46,240 --> 00:24:49,580
+decreasing aggregate expenditure decrease y
+
+304
+00:24:49,580 --> 00:24:55,840
+decrease money demand decrease r increase i so
+
+305
+00:24:55,840 --> 00:25:05,220
+it's not correct جرب البجي مش هتظبط تمام let's
+
+306
+00:25:05,220 --> 00:25:09,340
+go to this example
+
+307
+00:25:10,870 --> 00:25:17,330
+إذا كنت مهتمًا بأن دولة الانفلاش مرتفعة كثيرًا،
+
+308
+00:25:17,330 --> 00:25:22,710
+أي نوع من القرارات التالية يتم اقتراحها؟
+
+309
+00:25:26,730 --> 00:25:30,310
+النظام الوطني يجب أن يتخلص من المال المستعمل لأن
+
+310
+00:25:30,310 --> 00:25:35,710
+المال ليس لديه قيمة في الحالة هذه، صح؟ لذلك، نقترح
+
+311
+00:25:35,710 --> 00:25:39,030
+للنظام الوطني أن يستخدم قياس ومراعاة قياس ومراعاة
+
+312
+00:25:39,030 --> 00:25:39,110
+قياس ومراعاة قياس ومراعاة قياس ومراعاة قياس
+
+313
+00:25:39,110 --> 00:25:41,510
+ومراعاة قياس ومراعاة قياس ومراعاة قياس ومراعاة
+
+314
+00:25:41,510 --> 00:25:44,510
+قياس ومراعاة قياس ومراعاة قياس ومراعاة قياس
+
+315
+00:25:44,510 --> 00:25:49,750
+ومراعاة قياس ومراعاة قياس ومراعاة قياس ومراعاة
+
+316
+00:25:49,750 --> 00:25:54,070
+قياس ومراعاة قياس ومExpansion fiscal with
+
+317
+00:25:54,070 --> 00:25:58,050
+contractionary monetary Expansion fiscal يعني إزالة
+
+318
+00:25:58,050 --> 00:26:01,910
+تحويل الحكومة لإزالة تحويل المساعدة العامة إزالة Y
+
+319
+00:26:01,910 --> 00:26:07,930
+إزالة دعم مالية إزالة R وفي نفس الوقت
+
+320
+00:26:07,930 --> 00:26:13,330
+Contractionary monetary had expansionary fiscal
+
+321
+00:26:13,330 --> 00:26:19,990
+Contractionary monetary
+
+322
+00:26:22,420 --> 00:26:26,540
+ماذا نفعل؟ نعمل Decreasing لـ Money Supply نعمل
+
+323
+00:26:26,540 --> 00:26:30,380
+Decreasing لـ Money Supply نعمل Decreasing لـ
+
+324
+00:26:30,380 --> 00:26:38,760
+Money Supply نعمل Decreasing لـ Money Supply نعمل
+
+325
+00:26:38,760 --> 00:26:39,700
+Decreasing لـ Money Supply نعمل Decreasing لـ
+
+326
+00:26:39,700 --> 00:26:40,160
+Money Supply نعمل Decreasing لـ Money Supply نعمل
+
+327
+00:26:40,160 --> 00:26:40,640
+Decreasing لـ Money Supply نعمل Decreasing لـ
+
+328
+00:26:40,640 --> 00:26:40,700
+Money Supply نعمل Decreasing لـ Money Supply نعمل
+
+329
+00:26:40,700 --> 00:26:40,720
+Decreasing لـ Money Supply نعمل Decreasing لـ
+
+330
+00:26:40,720 --> 00:26:42,140
+Money Supply نعمل Decreasing لـ Money Supply نعمل
+
+331
+00:26:42,140 --> 00:26:47,140
+Decreasing لـ شو وضع ال why؟ شو وضع ال interest
+
+332
+00:26:47,140 --> 00:26:53,280
+rate؟ دي answer دي the output to either increase
+
+333
+00:26:53,280 --> 00:26:57,240
+or decrease or remain unchanged and the interest
+
+334
+00:26:57,240 --> 00:27:00,700
+rate is to increase ال interest rate أنت شوف شو
+
+335
+00:27:00,700 --> 00:27:04,140
+وضعه ال interest rate أنه increase هان increased
+
+336
+00:27:04,140 --> 00:27:07,660
+so the interest rate should increase but what
+
+337
+00:27:07,660 --> 00:27:13,760
+about why؟ why here increased؟ بالتالي، قد تتحرر أو
+
+338
+00:27:13,760 --> 00:27:20,440
+تتحرر أو تتغير أو يجب أن يكون عميق، أليس كذلك؟
+
+339
+00:27:20,440 --> 00:27:23,640
+قرار
+
+340
+00:27:23,640 --> 00:27:31,220
+مزعج من تجارب تجارب ومحافظة تجارب تجارب تجارب مع
+
+341
+00:27:31,220 --> 00:27:37,920
+محافظة تجارب هنا لدينا تجارب تجارب تجارب ومحافظة
+
+342
+00:27:37,920 --> 00:27:38,600
+تجارب
+
+343
+00:27:41,000 --> 00:27:43,800
+Expansion Monetary Expansion Monetary يعني إزالة
+
+344
+00:27:43,800 --> 00:27:50,980
+المصادر المالية تنقل R تنقل I تنقل تجارة الـ
+
+345
+00:27:50,980 --> 00:27:57,960
+Aggregate تنقل Y لذا ماذا عن Y وR؟ Y تنقل هنا
+
+346
+00:27:57,960 --> 00:28:01,680
+وتنقل هنا لذا بالتأكيد Y تنقل تجارة الـ Aggregate
+
+347
+00:28:01,680 --> 00:28:08,740
+لكن ماذا عن R؟ R يجب أن يكون مضمونًا لأن هنا تنقل
+
+348
+00:28:08,740 --> 00:28:16,030
+وتنقل لذلك ر قد تنقل وقد تنقل أو يبقى عادل صح؟ صح
+
+349
+00:28:16,030 --> 00:28:21,250
+شباب ولا في مشكلة؟ طيب a policy makes of a
+
+350
+00:28:21,250 --> 00:28:23,910
+contractionary fiscal and contractionary monetary
+
+351
+00:28:23,910 --> 00:28:29,270
+so we have contractionary fiscal with
+
+352
+00:28:29,270 --> 00:28:36,050
+contractionary monetary contractionary
+
+353
+00:28:36,050 --> 00:28:36,370
+fiscal
+
+354
+00:28:39,540 --> 00:28:43,380
+Decreasing G Decrease Aggregate Expenditure
+
+355
+00:28:43,380 --> 00:28:48,140
+Decrease Y Decrease Money Demand Decrease R
+
+356
+00:28:48,140 --> 00:28:53,660
+Increase I Contraction
+
+357
+00:28:53,660 --> 00:29:00,560
+of Monetary Decrease
+
+358
+00:29:00,560 --> 00:29:06,340
+Money Supply Increase R Decrease I Decrease
+
+359
+00:29:06,340 --> 00:29:13,570
+Aggregate Expenditure Decrease Y ماذا عن Y؟ تتخلص،
+
+360
+00:29:13,570 --> 00:29:21,610
+لذلك Y بالتأكيد ستتخلص، ولكن ماذا عن R؟ هنا تتخلص،
+
+361
+00:29:21,610 --> 00:29:31,390
+تزداد، لذلك يجب أن يكون مضمونًا، صحيح؟ دعنا
+
+362
+00:29:31,390 --> 00:29:31,710
+نقول
+
+363
+00:29:36,680 --> 00:29:39,360
+the policy mix that would cause the interest rate
+
+364
+00:29:39,360 --> 00:29:44,940
+to decrease؟ طب أنه فيهم هدولها ال policy mix that
+
+365
+00:29:44,940 --> 00:29:47,260
+would cause the interest rate to decrease and
+
+366
+00:29:47,260 --> 00:29:51,540
+investment to increase؟ بدك وقت بس احنا ماخدين هنا
+
+367
+00:29:51,540 --> 00:29:56,020
+إجابة، أنجرب contractual and fiscal، شو بدي أفعل؟
+
+368
+00:29:56,020 --> 00:30:00,680
+إيه؟ محلول فوق، تمام تمام هو المحلول هاجرب اللي هو
+
+369
+00:30:00,680 --> 00:30:04,660
+ال contractual fiscal policy contractual fiscal
+
+370
+00:30:04,660 --> 00:30:07,480
+policy means decreasing في ال government spending
+
+371
+00:30:07,480 --> 00:30:10,900
+هاي يوم هذا هو السؤال بيقول would cause the
+
+372
+00:30:10,900 --> 00:30:16,040
+interest rate to decrease هذا نزل ال interest rate
+
+373
+00:30:16,040 --> 00:30:20,400
+and the planned investment to increase But have
+
+374
+00:30:20,400 --> 00:30:26,220
+indeterminate effect on the aggregate output But
+
+375
+00:30:26,220 --> 00:30:30,480
+have
+
+376
+00:30:30,480 --> 00:30:33,480
+indeterminate effect on the aggregate output
+
+377
+00:30:43,320 --> 00:30:45,980
+ما هي الإجابة المطلوبة؟ مع expression and monetary
+
+378
+00:30:45,980 --> 00:30:47,880
+خلّينا نجرب expression and monetary ونشوف شو
+
+379
+00:30:47,880 --> 00:30:57,760
+الإجابة expressionary monetary increase
+
+380
+00:30:57,760 --> 00:31:02,780
+money supply increasing money supply decreased R
+
+381
+00:31:02,780 --> 00:31:06,480
+increased I increased aggregate expenditure
+
+382
+00:31:06,480 --> 00:31:11,080
+increased Y هلأ هو السؤال بيقول أنه وين ال policy
+
+383
+00:31:11,080 --> 00:31:13,260
+اللي بيكون فيه يعني ال interest rate decreased هلأ
+
+384
+00:31:13,260 --> 00:31:17,680
+شوف ال interest rate شو وضعه decreased ال planned
+
+385
+00:31:17,680 --> 00:31:25,720
+investment to increase هنا R مع R decreased I
+
+386
+00:31:25,720 --> 00:31:30,700
+increased و ال Y ambiguous increased and decreased
+
+387
+00:31:30,700 --> 00:31:37,260
+تمام؟ إيه هي هاي؟ هلأ ممكن أنا أستخدم شباب ال ISLM
+
+388
+00:31:39,110 --> 00:31:42,350
+أنه أعمل expansion fiscal مع contraction monetary
+
+389
+00:31:42,350 --> 00:31:49,050
+هذا هنشوفه كمان شوية نوصل الأفكار لنفس النتيجة طيب
+
+390
+00:31:49,050 --> 00:31:56,110
+let's go to this figure or diagram in
+
+391
+00:31:56,110 --> 00:31:58,990
+this diagram as you see there is an equilibrium in
+
+392
+00:31:58,990 --> 00:32:04,090
+the money market money demand note intersects
+
+393
+00:32:04,090 --> 00:32:06,590
+money supply suppose that the money demand
+
+394
+00:32:06,590 --> 00:32:11,070
+declined from MD0 to MD1 لأن أنت interested شو
+
+395
+00:32:11,070 --> 00:32:13,650
+بيصير فيه الـ decline دوة بتاعي الأهل الـ planned
+
+396
+00:32:13,650 --> 00:32:16,330
+investment بده increase طب شو اللي خلى ال money
+
+397
+00:32:16,330 --> 00:32:19,670
+demand ينزل خليني أشوف شو الأسئلة اللي موجودة
+
+398
+00:32:19,670 --> 00:32:23,770
+عندنا ال money demand curve will shift from MD0 to
+
+399
+00:32:23,770 --> 00:32:30,010
+MD1 إذا ما أعطينا مجموعة answers بتقولنا شو ال
+
+400
+00:32:30,010 --> 00:32:32,970
+reasons or causes بتخلي ال money demand أنه ينزل
+
+401
+00:32:36,310 --> 00:32:38,870
+Exactly، مظبوط، يعني اللي بيخلي ال money demand
+
+402
+00:32:38,870 --> 00:32:42,390
+ينزل، maybe ال income decreased، ال prices
+
+403
+00:32:42,390 --> 00:32:46,070
+decreased و ال number of transactions decreased أو
+
+404
+00:32:46,070 --> 00:32:48,710
+declined، مظبوط ولا لأ؟ And vice versa، لو بدي
+
+405
+00:32:48,710 --> 00:32:51,690
+أعمل ال increase في ال money demand، أو خلانا
+
+406
+00:32:51,690 --> 00:32:57,050
+نعملنا shifting من MD1 to MD0، شو له ده؟ Increase
+
+407
+00:32:57,050 --> 00:33:03,750
+the price exactly exactly so هذا ال answer is a
+
+408
+00:33:03,750 --> 00:33:07,390
+refer to the figure if the money demand curve
+
+409
+00:33:07,390 --> 00:33:11,330
+shifts from md0 to md1 شو اللي بيصير فيه ال planned
+
+410
+00:33:11,330 --> 00:33:15,850
+investment و ال aggregate output شوف شو له ده هذا
+
+411
+00:33:15,850 --> 00:33:18,330
+ال answer دي أنه ال planned investment will
+
+412
+00:33:18,330 --> 00:33:21,790
+increase and aggregate output will increase السؤال
+
+413
+00:33:21,790 --> 00:33:27,620
+أنه فينا shifting من md0 ل md1 ده ارجع لرسمه هيك من
+
+414
+00:33:27,620 --> 00:33:33,460
+MD note ل MD one شو ال FX on ال aggregate output
+
+415
+00:33:33,460 --> 00:33:39,940
+هو بده ال FX ولا بده ال reasons؟ اه شو بده يصير في
+
+416
+00:33:39,940 --> 00:33:42,360
+ال planned investment ال decreasing اللي صار في ال
+
+417
+00:33:42,360 --> 00:33:46,690
+money demand شو بيعمل في ال interest rate؟ R
+
+418
+00:33:46,690 --> 00:33:51,710
+decline increased I increased aggregate
+
+419
+00:33:51,710 --> 00:33:56,150
+expenditure increased Y. So Y would increase, the
+
+420
+00:33:56,150 --> 00:33:57,490
+interest rate would decline, the planned
+
+
+421
+00:33:57,490 --> 00:34:00,610
+investment would increase. الإجابات دي أن ال
+
+422
+00:34:00,610 --> 00:34:04,090
+planned investment will increase and Y would
+
+423
+00:34:04,090 --> 00:34:06,230
+increase صح؟
+
+424
+00:34:10,600 --> 00:34:13,400
+Okay هذا السؤال كمان أَجَاءَ بالـ .. بالـ exam المرة
+
+425
+00:34:13,400 --> 00:34:16,360
+الماضية من ضمن الأشياء اللي .. اللي أَجَاءَت بالـ
+
+426
+00:34:16,360 --> 00:34:19,120
+multiple choice which of the following sequence of
+
+427
+00:34:19,120 --> 00:34:22,460
+any events is it true? increasing P leads to
+
+428
+00:34:22,460 --> 00:34:24,520
+increasing money demand, decrease money demand,
+
+429
+00:34:24,620 --> 00:34:27,060
+decrease R and so on فالـ .. الـ .. الـ correct
+
+430
+00:34:27,060 --> 00:34:29,580
+answer اللي هو increasing Y leads to increasing
+
+431
+00:34:29,580 --> 00:34:33,050
+money demand to increasing R، مظبوط؟ هي لأنه زيادة
+
+432
+00:34:33,050 --> 00:34:36,070
+في الـ Y بيزود الـ money demand increase R طب لو
+
+433
+00:34:36,070 --> 00:34:39,830
+أَجَرّب أي نقطة أي أشياء ثانية for the first case A
+
+434
+00:34:39,830 --> 00:34:43,370
+increasing P شو بتعمل في الـ money demand increased
+
+435
+00:34:43,370 --> 00:34:50,150
+لإن هذا غلط لإن الـ increasing في الـ price increase
+
+436
+00:34:50,150 --> 00:34:54,010
+money demand increase R لإن هتلاقوا فيه جزئية لـ
+
+437
+00:34:54,010 --> 00:35:00,820
+يُمكن فيها خطأ صح؟ فكونوا حذرين في الأسئلة هذه طيب
+
+438
+00:35:00,820 --> 00:35:04,360
+the price or at the price level of the economy
+
+439
+00:35:04,360 --> 00:35:10,960
+increased or as .. as the price level of the
+
+440
+00:35:10,960 --> 00:35:13,120
+economy increased which of the following sequence
+
+441
+00:35:13,120 --> 00:35:20,060
+of events occurs؟ زيادة الـ price شو بتعمل؟ استخدام
+
+442
+00:35:20,060 --> 00:35:25,660
+البرنامج لإزالة الأسعار باستخدام البرنامج لإزالة 
+
+443
+00:35:25,660 --> 00:35:32,420
+الأسعار
+
+444
+00:35:32,660 --> 00:35:36,620
+شو الـ answer C اللي هو هي increased money demand
+
+445
+00:35:36,620 --> 00:35:39,080
+increased R decreased I decreased aggregate
+
+446
+00:35:39,080 --> 00:35:42,380
+expenditure if you would like to complete decrease
+
+447
+00:35:42,380 --> 00:35:46,000
+Y طيب as the price level of the economy decreases
+
+448
+00:35:46,000 --> 00:35:49,800
+which is of the following sequence of events
+
+449
+00:35:49,800 --> 00:35:53,280
+occurs اللي هو دي إنه decreasing في الـ prices شو
+
+450
+00:35:53,280 --> 00:35:59,650
+بتعمل؟ Decreased Money Demand Decreased R Increased
+
+451
+00:35:59,650 --> 00:36:05,250
+I Increased Aggregate Expenditure أو Aggregate
+
+452
+00:36:05,250 --> 00:36:11,470
+Demand إذا فالجواب الأصح هو D Aggregate
+
+453
+00:36:11,470 --> 00:36:16,070
+Demand يرتفع عندما ترتفع قيمة اللغة لأن قيمة اللغة آسفة
+
+454
+00:36:16,070 --> 00:36:25,290
+تقل قيمة اللغة آسفة تقل قيمة اللغة
+
+455
+00:36:25,290 --> 00:36:28,320
+آسفة خليني أحل الـ decreasing في الـ prices، بقول الـ
+
+456
+00:36:28,320 --> 00:36:33,860
+aggregate demand هذا زاد نتيجة أن الـ price نزل،
+
+457
+00:36:33,860 --> 00:36:38,620
+هذا وين؟ أثر على مين؟ طبعًا هذا because the lower
+
+458
+00:36:38,620 --> 00:36:42,460
+price level causes what؟ causes money demand to
+
+459
+00:36:42,460 --> 00:36:49,050
+decrease أو to decrease investment to increase هي
+
+460
+00:36:49,050 --> 00:36:53,850
+الإجابة، مظبوط؟ إذا which one دي؟ إنه الانزول في
+
+461
+00:36:53,850 --> 00:36:55,790
+الـ prices هذا، الـ decreasing في الـ prices، شو
+
+462
+00:36:55,790 --> 00:37:00,590
+يعمل؟ Causes the demand for money to fall, causing
+
+463
+00:37:00,590 --> 00:37:02,110
+the interest rate to fall
+
+464
+00:37:07,620 --> 00:37:10,780
+طيب الـ aggregate demand decreased when the price
+
+465
+00:37:10,780 --> 00:37:13,660
+level rises لحالة المعاكسة because إنه الـ money
+
+466
+00:37:13,660 --> 00:37:18,400
+demand إنه اللي طُلوع في الـ prices شو أثر زاد الـ
+
+467
+00:37:18,400 --> 00:37:21,240
+money demand و زاد الـ interest rate عشان هيك الـ
+
+468
+00:37:21,240 --> 00:37:26,920
+aggregate demand نزل صعب
+
+469
+00:37:26,920 --> 00:37:32,360
+الأمور طيب سألك كويس طيب an increase in the money
+
+470
+00:37:32,360 --> 00:37:35,220
+supply will cause the planned investment to what؟
+
+471
+00:37:36,420 --> 00:37:39,920
+to increase أكيد لإنه هاي الـ increasing في المال
+
+472
+00:37:39,920 --> 00:37:45,270
+الـ supply Decrease are increase in planned
+
+473
+00:37:45,270 --> 00:37:48,330
+investment, increased aggregate expenditure or
+
+474
+00:37:48,330 --> 00:37:52,290
+aggregate demand, and increasing Y طب الـ
+
+475
+00:37:52,290 --> 00:37:56,030
+consumption add consumption to what؟ to increase
+
+476
+00:37:56,030 --> 00:38:00,050
+exactly لأن الـ Y increased أو هو نفس الـ aggregate
+
+477
+00:38:00,050 --> 00:38:02,950
+demand أو it's part of the aggregate demand so it
+
+478
+00:38:02,950 --> 00:38:06,390
+should increase طيب the level of aggregate output
+
+479
+00:38:06,390 --> 00:38:11,780
+demanded falls when the price level rises because
+
+480
+00:38:11,780 --> 00:38:15,620
+the resulting increased interest rate will lead to
+
+481
+00:38:15,620 --> 00:38:19,840
+what؟ شفتوا التحليل هذا؟ إنه بيقولنا لو الـ
+
+482
+00:38:19,840 --> 00:38:22,980
+aggregate output demanded falls اللي الـ Y نزلت
+
+483
+00:38:22,980 --> 00:38:30,200
+نتيجة إنه الـ prices rises لأنه الارتفاع اللي صار في
+
+484
+00:38:30,200 --> 00:38:33,180
+الـ interest rate عمل شو؟ عمل decreasing في الـ
+
+485
+00:38:33,180 --> 00:38:36,140
+planned investment صح؟ ومن ثم decreasing في الـ
+
+486
+00:38:36,140 --> 00:38:41,980
+aggregate expenditure أو الـ consumption طيب each
+
+487
+00:38:41,980 --> 00:38:46,800
+point on LM curve represent the equilibrium in the
+
+488
+00:38:46,800 --> 00:38:50,460
+أنه ماركت؟ الـ LM العلاقة بمين؟ بالـ money market
+
+489
+00:38:50,460 --> 00:38:53,300
+بالـ money market صحيح طيب الـ IS أو خلينا نروح للـ
+
+490
+00:38:53,300 --> 00:38:59,760
+diagram هذا in
+
+491
+00:38:59,760 --> 00:39:10,100
+this figure we have IS LM curves and there is We
+
+492
+00:39:10,100 --> 00:39:13,620
+have an equilibrium interest rate and equilibrium
+
+493
+00:39:13,620 --> 00:39:20,280
+على الـ IS وين بتعملوا lift؟ shift أو shifting أو
+
+494
+00:39:20,280 --> 00:39:23,520
+أين؟ rightward if we use an expansion fiscal
+
+495
+00:39:23,520 --> 00:39:29,340
+policy IS will shift to the right to IS too قبل
+
+496
+00:39:29,340 --> 00:39:35,900
+expansionary monetary بأثر على مين؟ rightward
+
+497
+00:39:35,900 --> 00:39:40,570
+shifting للـ LM ممكن يكونوا جد بعض ممكن يكونوا أقل
+
+498
+00:39:40,570 --> 00:39:47,390
+من بعض أو أكثر صح؟ صح يعني طب في هاي الحالة شو
+
+499
+00:39:47,390 --> 00:39:52,690
+اللي شايفينه أنتم؟ يعني لو كانت أنا هيك أو هي
+
+500
+00:39:52,690 --> 00:39:56,510
+أو هي
+
+501
+00:39:56,510 --> 00:40:00,050
+why in all cases would increase؟ لأن وإحنا
+
+502
+00:40:00,050 --> 00:40:02,770
+مستخدمين expansion .. expansion fiscal مع
+
+503
+00:40:02,770 --> 00:40:05,450
+expansion monetary بس الـ interest rate is
+
+504
+00:40:05,450 --> 00:40:10,160
+ambiguous مظبوط؟ صح طيب لو كان عندي الوضع هيك إن
+
+505
+00:40:10,160 --> 00:40:15,160
+إحنا مستخدمين expansion fiscal with contractionary
+
+506
+00:40:15,160 --> 00:40:20,420
+monetary يعني suppose الوضع هيك we use an
+
+507
+00:40:20,420 --> 00:40:23,540
+expansion fiscal بأثر على مين الـ expansion fiscal
+
+508
+00:40:23,540 --> 00:40:29,660
+where exactly
+
+509
+00:40:29,660 --> 00:40:35,600
+إذا وين هنروح rightward shifting لمين للـ IS هذا
+
+510
+00:40:35,600 --> 00:40:40,390
+expansion fiscal to IS2 هذا expansion of the fascia
+
+511
+00:40:40,390 --> 00:40:44,710
+طيب contractionary monetary و بدي أعمل three cases
+
+512
+00:40:44,710 --> 00:40:48,290
+جد بعض أكبر من بعض أقل من بعض exactly leftward
+
+513
+00:40:48,290 --> 00:40:52,130
+shifting to the LM curve يعني خلينا نجيب و هيك مرة
+
+514
+00:40:52,130 --> 00:41:05,710
+smaller جد بعض أكبر الـ M3 الـ M2 الـ M3 الـ M4 خذ الـ
+
+515
+00:41:05,710 --> 00:41:06,310
+first case
+
+516
+00:41:10,280 --> 00:41:13,560
+هنا R زي زي زي زي زي زي زي زي زي زي زي زي زي زي
+
+517
+00:41:13,560 --> 00:41:16,760
+زي زي زي زي
+
+518
+00:41:23,850 --> 00:41:28,690
+هن why decreased and why increased in all cases if
+
+519
+00:41:28,690 --> 00:41:32,030
+we use an expansion fiscal policy with contraction
+
+520
+00:41:32,030 --> 00:41:36,210
+and monetary policy in this case our would increase
+
+521
+00:41:36,210 --> 00:41:40,830
+and why ambiguous exactly طب لو استخدمنا
+
+522
+00:41:40,830 --> 00:41:45,650
+contraction مع contraction why would decline و لا
+
+523
+00:41:45,650 --> 00:41:52,150
+R و should ambiguous طيب let's go to the exercises
+
+524
+00:42:02,140 --> 00:42:05,380
+طيب refer to the figure an expansion fiscal policy
+
+525
+00:42:05,380 --> 00:42:10,240
+shifts فراغ space curve to the what؟ الـ expansion
+
+526
+00:42:10,240 --> 00:42:16,280
+fiscal شو بتعمل؟ IS to the right that's it طيب الـ
+
+527
+00:42:16,280 --> 00:42:24,440
+contractionary monetary الـ LM to left exactly as a
+
+528
+00:42:24,440 --> 00:42:28,180
+result of space the equilibrium interest rate
+
+529
+00:42:28,180 --> 00:42:31,340
+increased and the equilibrium output level
+
+530
+00:42:31,340 --> 00:42:33,620
+increased يعني شو الحالة اللي بيصير في عندنا
+
+531
+00:42:33,620 --> 00:42:37,040
+increasing بالـ interest rate و increasing في الـ
+
+532
+00:42:37,040 --> 00:42:43,580
+aggregate output سياسة توسعية في إيش expenditure
+
+533
+00:42:43,580 --> 00:42:48,840
+fiscal جرب الـ expenditure fiscal هاي الـ ISLM this
+
+534
+00:42:48,840 --> 00:43:01,270
+is IS one LM one E1 R1 Y1 جرب كل الـ policies مش الـ
+
+535
+00:43:01,270 --> 00:43:04,170
+mixed العادية maybe expansionary contractionary
+
+536
+00:43:04,170 --> 00:43:10,810
+and so on لو جربنا expansion fiscal rightward
+
+537
+00:43:10,810 --> 00:43:20,110
+shifting لمين للـ IS to IS2 here E2 R2 Y2 so وين الـ
+
+538
+00:43:20,110 --> 00:43:22,390
+R increase و الـ Y increase في الـ expansion fiscal
+
+539
+00:43:23,320 --> 00:43:30,080
+طب لو استخدمنا contractionary fiscal R يتقلص و Y
+
+540
+00:43:30,080 --> 00:43:37,740
+يتقلص طيب تمام هي كده واضحة الأمور؟ طيب هذا نفس
+
+541
+00:43:37,740 --> 00:43:41,740
+السؤال which of the policy mixed؟ طيب هدف الـ
+
+542
+00:43:41,740 --> 00:43:45,340
+policy mixed و بنستخدمه على الـ IS و LM على الـ
+
+543
+00:43:45,340 --> 00:43:51,270
+policy mixed Which policy mixed would definitely
+
+544
+00:43:51,270 --> 00:43:55,930
+increase the equilibrium interest rate؟ هنقول
+
+545
+00:43:55,930 --> 00:43:59,450
+المؤكد هيزود الـ interest rate طبقناها قبل شوية في
+
+546
+00:43:59,450 --> 00:44:03,110
+الـ policy mixed اللي هو خليني آخذ الإجابة و نرجع
+
+547
+00:44:03,110 --> 00:44:06,350
+الفاعل و نتأكد منها مظبوط ولا لأ الـ expansion of
+
+548
+00:44:06,350 --> 00:44:08,590
+fiscal and contraction of monetary اللي طبقناها
+
+549
+00:44:08,590 --> 00:44:13,290
+قبل شوية expansion of fiscal مع
+
+550
+00:44:13,290 --> 00:44:16,430
+contractionary monetary نجربها على الرسم نشوف شو
+
+551
+00:44:16,430 --> 00:44:20,970
+الوضع هل فعلاً بتزيد الـ interest rate definitely؟
+
+552
+00:44:20,970 --> 00:44:25,530
+expansion fiscal شو بتعمل؟ rightward shifting لـ الـ
+
+553
+00:44:25,530 --> 00:44:32,570
+IS to IS2 طب contractionary monetary ممكن يكون هيك
+
+554
+00:44:32,570 --> 00:44:42,850
+maybe هيك for the first case R increased طب لو
+
+555
+00:44:42,850 --> 00:44:43,550
+جربنا هنا
+
+556
+00:44:47,300 --> 00:44:52,100
+الثالثة حالة برضه اكتشفنا صح؟ بس الـ why is ambiguous
+
+557
+00:44:52,100 --> 00:44:57,040
+صح؟ طيب الـ curve that illustrates the positive
+
+558
+00:44:57,040 --> 00:45:00,760
+relationship between the equilibrium values of
+
+559
+00:45:00,760 --> 00:45:03,120
+aggregate output and the interest rate أنا اللي
+
+560
+00:45:03,120 --> 00:45:05,060
+بأعمله؟ الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. الـ .. 
+
+561
+00:45:05,060 --> 00:45:06,100
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+562
+00:45:06,100 --> 00:45:07,020
+.. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال ..
+
+563
+00:45:07,020 --> 00:45:07,620
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+564
+00:45:07,620 --> 00:45:08,020
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال .. ال
+
+565
+00:45:08,020 --> 00:45:09,750
+ال .. ال .. ال .. ال .. ال .. ال .. ال .. الـ IS
+
+566
+00:45:09,750 --> 00:45:14,210
+curve تظهر مجموعة من الإنترنت ومجموعة من الإنترنت 
+
+567
+00:45:14,210 --> 00:45:21,010
+مرتبطة بالإيقاليبيوم في مجموعة المال، فالس هذا مش
+
+568
+00:45:21,010 --> 00:45:24,650
+الـ IS طيب إذا تتقل المعقدة المالية فالـ curve
+
+569
+00:45:24,650 --> 00:45:31,230
+للمالية تتقل يعني تتقل في المعقدة المالية بيعمل 
+
+570
+00:45:31,230 --> 00:45:35,430
+decreasing في الـ LM مظبوط طيب إذا تتقل المعقدة
+
+571
+00:45:35,430 --> 00:45:36,010
+المالية تتقل 
+
+572
+00:45:38,560 --> 00:45:41,080
+حقًا لأنها تجارب تجارب تجارب تجارب تجارب تجارب
+
+573
+00:45:41,080 --> 00:45:46,820
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+574
+00:45:46,820 --> 00:45:49,260
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+575
+00:45:49,260 --> 00:45:51,980
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+576
+00:45:51,980 --> 00:45:52,000
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+577
+00:45:52,000 --> 00:46:01,960
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+578
+00:46:01,960 --> 00:46:05,220
+ت
+
+579
+00:46:06,740 --> 00:46:11,880
+إذا تزوية الحكومة تزوى، فالـ IS curve تزوى صحيح
+
+580
+00:46:11,880 --> 00:46:13,060
+يعطيكم العجز 
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/PziFuZwogc8_raw.json b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/PziFuZwogc8_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..1f04580553aeb2439b96b93f60c61eae1c647035
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/PziFuZwogc8_raw.json
@@ -0,0 +1 @@
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"text": "This leads to increase in money supply, decrease R, increase I So it should be correct طب لو جربنا اشي تاني for the first case او the second case اشي جديد، ده بيخد اي case بيلاقي مش مطابق، لا ينطبق", "tokens": [51, 18300, 6689, 281, 3488, 294, 1460, 5847, 11, 11514, 497, 11, 3488, 286, 407, 309, 820, 312, 3006, 23032, 3555, 45164, 10874, 25513, 8315, 1975, 8592, 1829, 6055, 7649, 1829, 337, 264, 700, 1389, 1975, 2407, 264, 1150, 1389, 1975, 8592, 1829, 10874, 16254, 3215, 12399, 11778, 3224, 4724, 1829, 9778, 3215, 1975, 1829, 1389, 4724, 1829, 15040, 38436, 37893, 3714, 9566, 16758, 4587, 12399, 20193, 7251, 1863, 9566, 3555, 4587], "avg_logprob": -0.37628423677731865, "compression_ratio": 1.3621621621621622, "no_speech_prob": 0.0, "words": [{"start": 305.23, "end": 306.07, "word": "This", "probability": 0.47320556640625}, {"start": 306.07, "end": 306.29, "word": " leads", "probability": 0.401611328125}, {"start": 306.29, "end": 306.43, "word": " to", "probability": 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"temperature": 1.0}, {"id": 14, "seek": 35488, "start": 325.92, "end": 354.88, "text": "طيب، which of the following sequence of events follows an expansionary monitor policy؟ هذا السؤال جاء في الامتحان بال multiple choice العام الماضي زي هيك و خلّيني أخد different cases عليه السؤال إيش بيقول؟ انه expansionary monitor policy أنه فيهم يتبع ل expansionary monitor policy expansionary monitor policy means the increasing money supply", "tokens": [9566, 1829, 3555, 12399, 597, 295, 264, 3480, 8310, 295, 3931, 10002, 364, 11260, 822, 6002, 3897, 22807, 23758, 21136, 33604, 6027, 10874, 16606, 8978, 2423, 10943, 2655, 5016, 7649, 20666, 3866, 3922, 18863, 10943, 9673, 46958, 1829, 30767, 1829, 39896, 4117, 4032, 16490, 1211, 11703, 9957, 1829, 5551, 9778, 3215, 819, 3331, 47356, 2423, 3794, 33604, 6027, 11933, 1829, 8592, 4724, 1829, 39648, 22807, 16472, 3224, 11260, 822, 6002, 3897, 14739, 3224, 8978, 16095, 7251, 2655, 3555, 3615, 5296, 11260, 822, 6002, 3897, 11260, 822, 6002, 3897, 1355, 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D. 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1126.13, "word": " aggregate", "probability": 0.89404296875}, {"start": 1126.13, "end": 1126.69, "word": " expenditure", "probability": 0.98388671875}, {"start": 1126.69, "end": 1127.13, "word": " two", "probability": 0.861328125}, {"start": 1127.13, "end": 1128.27, "word": " قدش", "probability": 0.7176106770833334}, {"start": 1128.27, "end": 1128.49, "word": " كان", "probability": 0.99658203125}, {"start": 1128.49, "end": 1128.61, "word": " ال", "probability": 0.94873046875}, {"start": 1128.61, "end": 1128.85, "word": " y", "probability": 0.41259765625}, {"start": 1128.85, "end": 1130.35, "word": " 200", "probability": 0.33935546875}, {"start": 1130.35, "end": 1131.31, "word": " و", "probability": 0.705078125}, {"start": 1131.31, "end": 1131.41, "word": " ل", "probability": 0.47314453125}, {"start": 1131.41, "end": 1131.63, "word": " new", "probability": 0.76220703125}, {"start": 1131.63, "end": 1132.03, "word": " y", "probability": 0.92236328125}, {"start": 1132.03, "end": 1132.97, "word": " 400", "probability": 0.95556640625}, {"start": 1132.97, "end": 1135.29, "word": " هلا", "probability": 0.573974609375}, {"start": 1135.29, "end": 1135.43, "word": " في", "probability": 0.86181640625}, {"start": 1135.43, "end": 1135.61, "word": " هاي", "probability": 0.569091796875}, {"start": 1135.61, "end": 1136.11, "word": " الحالة", "probability": 0.9934895833333334}], "temperature": 1.0}, {"id": 44, "seek": 115465, "start": 1137.31, "end": 1154.65, "text": "في عندى crowding out إذا بدى أعرف إنه كان في عندى crowding out ولا لأ شباب بدى أجيب بدى أستخدم قانون ال multiplier ال governance funding multiplier delta y over delta g", "tokens": [41185, 43242, 7578, 6401, 3584, 484, 11933, 15730, 47525, 7578, 5551, 3615, 28480, 36145, 3224, 25961, 8978, 43242, 7578, 6401, 3584, 484, 49429, 5296, 10721, 13412, 3555, 16758, 47525, 7578, 5551, 7435, 1829, 3555, 47525, 7578, 5551, 14851, 9778, 40448, 12174, 7649, 11536, 2423, 44106, 2423, 17449, 6137, 44106, 8289, 288, 670, 8289, 290], 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"probability": 0.87060546875}, {"start": 1207.36, "end": 1208.22, "word": " بس", "probability": 0.95556640625}, {"start": 1208.22, "end": 1208.4, "word": " لو", "probability": 0.986328125}, {"start": 1208.4, "end": 1208.62, "word": " راح", "probability": 0.91552734375}, {"start": 1208.62, "end": 1209.04, "word": " زاد", "probability": 0.991455078125}, {"start": 1209.04, "end": 1209.52, "word": " هيك", "probability": 0.947021484375}, {"start": 1209.52, "end": 1210.04, "word": " بعدين", "probability": 0.785888671875}, {"start": 1210.04, "end": 1210.5, "word": " نرجع", "probability": 0.8507486979166666}, {"start": 1210.5, "end": 1210.98, "word": " شوية", "probability": 0.8260091145833334}], "temperature": 1.0}, {"id": 47, "seek": 124049, "start": 1212.91, "end": 1240.49, "text": "وصار عندي ال y هيك 180 بيكون في عندي crowding out طبعا؟ طيب yes بيكون مش مخطط لأ بيكون أنا مخطط أزوده هنا باللأ ل 400 بس ما زادش ال 400 زاد ل 380 صح؟ يعني سببز أن هذا هيك 380؟ طيب طب سببز أن الوضع ماكانش هيك", 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original point was at E1 here وهذا ال aggregate expenditure note هي ال initial تمام؟", "tokens": [2304, 19913, 3555, 2407, 9566, 20328, 5016, 1829, 5016, 39896, 31767, 5016, 1975, 3224, 31439, 39896, 294, 341, 1389, 456, 307, 572, 6401, 3584, 1802, 23032, 1829, 3555, 7297, 264, 5883, 37495, 22653, 2423, 2407, 11242, 3615, 25961, 3714, 46456, 46538, 264, 5883, 420, 264, 3380, 935, 390, 412, 462, 16, 510, 37037, 15730, 2423, 26118, 40377, 3637, 39896, 2423, 5883, 46811, 10943, 22807], "avg_logprob": -0.23966346153846155, "compression_ratio": 1.4293193717277486, "no_speech_prob": 0.0, "words": [{"start": 1250.3700000000001, "end": 1251.21, "word": "مظبوط", "probability": 0.6629638671875}, {"start": 1251.21, "end": 1252.05, "word": " صحيح", "probability": 0.827392578125}, {"start": 1252.05, "end": 1252.21, "word": " هي", "probability": 0.459228515625}, {"start": 1252.21, "end": 1252.53, "word": " الصح", "probability": 0.896484375}, {"start": 1252.53, "end": 1253.21, "word": " اه", 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0.80029296875}, {"start": 1259.75, "end": 1260.27, "word": " the", "probability": 0.42626953125}, {"start": 1260.27, "end": 1260.85, "word": " initial", "probability": 0.90673828125}, {"start": 1260.85, "end": 1261.27, "word": " يعني", "probability": 0.9453125}, {"start": 1261.27, "end": 1261.55, "word": " الوضع", "probability": 0.98486328125}, {"start": 1261.55, "end": 1261.79, "word": " كان", "probability": 0.990234375}, {"start": 1261.79, "end": 1262.37, "word": " مختلف", "probability": 0.9939778645833334}, {"start": 1262.37, "end": 1262.81, "word": " the", "probability": 0.265625}, {"start": 1262.81, "end": 1263.33, "word": " initial", "probability": 0.859375}, {"start": 1263.33, "end": 1263.55, "word": " or", "probability": 0.8427734375}, {"start": 1263.55, "end": 1263.67, "word": " the", "probability": 0.85595703125}, {"start": 1263.67, "end": 1264.03, "word": " original", "probability": 0.92724609375}, {"start": 1264.03, "end": 1264.53, "word": " point", "probability": 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fiscal policy مالهاش علاقة", "tokens": [25957, 1211, 2655, 5662, 8978, 2423, 39184, 49, 4032, 23223, 8978, 2423, 39184, 40, 37037, 15730, 13672, 1829, 41850, 5551, 9381, 15040, 47525, 13063, 47356, 5296, 33456, 3224, 20328, 9640, 8978, 3224, 5551, 9381, 15040, 2423, 23223, 13672, 1829, 20328, 9640, 8978, 26118, 40377, 2445, 8717, 31371, 7435, 3660, 14739, 3224, 2423, 1393, 6078, 8717, 11622, 1211, 23032, 3555, 45164, 13412, 38688, 2423, 1867, 363, 2423, 37372, 295, 15897, 3897, 8032, 1211, 37372, 295, 15897, 3897, 19446, 1211, 3224, 33599, 11203, 995, 28671], "avg_logprob": -0.30580355865614756, "compression_ratio": 1.6593886462882097, "no_speech_prob": 1.1920928955078125e-07, "words": [{"start": 1461.44, "end": 1461.94, "word": "عملت", "probability": 0.55224609375}, {"start": 1461.94, "end": 1462.48, "word": " increasing", "probability": 0.6591796875}, {"start": 1462.48, "end": 1462.72, "word": " في", "probability": 0.849609375}, {"start": 1462.72, "end": 1463.0, "word": " الـR", 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decreasing g مثلا leads to decreasing aggregate expenditure decrease y decrease money demand decrease r increase i so it's not correct جرب البجي مش هتظبط تمام let's go to this example", "tokens": [6027, 20292, 39896, 3224, 23223, 290, 50113, 15040, 6689, 281, 23223, 26118, 40377, 11514, 288, 11514, 1460, 4733, 11514, 367, 3488, 741, 370, 309, 311, 406, 3006, 10874, 25513, 29739, 7435, 1829, 37893, 8032, 2655, 19913, 3555, 9566, 46811, 10943, 718, 311, 352, 281, 341, 1365], "avg_logprob": -0.3819813702968841, "compression_ratio": 1.4050632911392404, "no_speech_prob": 0.0, "words": [{"start": 1481.18, "end": 1481.44, "word": "اللي", "probability": 0.325927734375}, {"start": 1481.44, "end": 1481.82, "word": " هيه", "probability": 0.60302734375}, {"start": 1481.82, "end": 1483.02, "word": " decreasing", "probability": 0.3994140625}, {"start": 1483.02, "end": 1484.0, "word": " g", "probability": 0.2432861328125}, {"start": 1484.0, "end": 1485.14, "word": " مثلا", "probability": 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investment to increase", "tokens": [9778, 1211, 11703, 9957, 1829, 5551, 5016, 1211, 2423, 23223, 8978, 2423, 7901, 12399, 4724, 39648, 2423, 26118, 4733, 23758, 30767, 18513, 8717, 31371, 7435, 3660, 14739, 2423, 3218, 8717, 11622, 1211, 12399, 23758, 4032, 9957, 22807, 5551, 49115, 15844, 3714, 9957, 22807, 23032, 3555, 3615, 995, 23758, 570, 264, 3126, 3218, 1496, 7700, 437, 22807, 7700, 1460, 4733, 281, 11514, 420, 281, 11514, 6078, 281, 3488], "avg_logprob": -0.2275965018745731, "compression_ratio": 1.5353535353535352, "no_speech_prob": 0.0, "words": [{"start": 2185.6, "end": 2185.96, "word": "خلّيني", "probability": 0.88330078125}, {"start": 2185.96, "end": 2186.22, "word": " أحل", "probability": 0.8307291666666666}, {"start": 2186.22, "end": 2186.38, "word": " ال", "probability": 0.51806640625}, {"start": 2186.38, "end": 2186.98, "word": " decreasing", "probability": 0.26904296875}, {"start": 2186.98, "end": 2187.14, "word": " في", "probability": 0.828125}, {"start": 2187.14, 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2724.65, "word": " curve", "probability": 0.62353515625}, {"start": 2724.65, "end": 2725.15, "word": " للمالية", "probability": 0.403167724609375}, {"start": 2725.15, "end": 2725.99, "word": " تتقل", "probability": 0.8482666015625}, {"start": 2725.99, "end": 2727.97, "word": " يعني", "probability": 0.590087890625}, {"start": 2727.97, "end": 2728.35, "word": " تتقل", "probability": 0.70489501953125}, {"start": 2728.35, "end": 2728.55, "word": " في", "probability": 0.75390625}, {"start": 2728.55, "end": 2729.19, "word": " المعقدة", "probability": 0.93505859375}, {"start": 2729.19, "end": 2729.19, "word": " المالية", "probability": 0.9562174479166666}, {"start": 2729.19, "end": 2731.23, "word": " بيعمل", "probability": 0.921630859375}, {"start": 2731.23, "end": 2731.75, "word": " decreasing", "probability": 0.650390625}, {"start": 2731.75, "end": 2731.95, "word": " في", "probability": 0.8544921875}, {"start": 2731.95, "end": 2732.03, "word": " ال", "probability": 0.5078125}, {"start": 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2767.2, "word": " تزوية", "probability": 0.2413787841796875}, {"start": 2767.2, "end": 2767.7, "word": " الحكومة", "probability": 0.7562255859375}, {"start": 2767.7, "end": 2769.88, "word": " تزوى،", "probability": 0.4703125}, {"start": 2769.88, "end": 2770.18, "word": " فالـ", "probability": 0.3778483072916667}, {"start": 2770.18, "end": 2770.54, "word": " IS", "probability": 0.6044921875}, {"start": 2770.54, "end": 2770.84, "word": " curve", "probability": 0.8525390625}, {"start": 2770.84, "end": 2771.22, "word": " تزوى", "probability": 0.76361083984375}, {"start": 2771.22, "end": 2771.88, "word": " صحيح", "probability": 0.7884521484375}, {"start": 2771.88, "end": 2772.68, "word": " يعطيكم", "probability": 0.7372233072916666}, {"start": 2772.68, "end": 2773.06, "word": " العجز", "probability": 0.3765055338541667}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2774.8775, "duration_after_vad": 2610.5218749999917}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/SRYAT9ODXjs_postprocess.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/SRYAT9ODXjs_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..d9a4952dc0f280346f9379e7331d4c22d1e8b6cb
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/SRYAT9ODXjs_postprocess.srt
@@ -0,0 +1,1880 @@
+1
+00:00:20,700 --> 00:00:24,500
+اليوم ان شاء الله سنكمل الحلقة السادسة، Money
+
+2
+00:00:24,500 --> 00:00:30,380
+Supply و Federal Reserve System في هذه الدراسة،
+
+3
+00:00:30,380 --> 00:00:34,620
+سنركز على الـ Money Multiplier و الأدوات المختلفة
+
+4
+00:00:34,620 --> 00:00:36,860
+التي يستخدمها الشركة الرئيسية أو Federal Reserve
+
+5
+00:00:36,860 --> 00:00:44,180
+System لتحكم مصادر الماللتفهم المصطلح المالي مالتي
+
+6
+00:00:44,180 --> 00:00:49,000
+بلاير دعنا نأخذ المثال التالف لكي نفهم المصطلح
+
+7
+00:00:49,000 --> 00:00:57,480
+والفكرة، فاعترض ان بعض منكم لديه 100 ألف دولار
+
+8
+00:00:57,480 --> 00:01:07,090
+فاعترض ان محمد لديه 100 ألف دولاروهي تدفع هذه
+
+9
+00:01:07,090 --> 00:01:13,830
+المقاومة لبنك فلسطين بنك واحد بنك رقم واحد كدفعة
+
+10
+00:01:13,830 --> 00:01:20,270
+جديدة في هذه الحالة البنك الرئيسي أو بنك واحد بنك
+
+11
+00:01:20,270 --> 00:01:27,590
+رقم واحد يجب أن يدفع المقاومة المطلوبة ويدفعها
+
+12
+00:01:27,590 --> 00:01:35,160
+كمقاومة في بنك الرئيسي صح؟بالنسبة لـ 5000$ ففي هذه
+
+13
+00:01:35,160 --> 00:01:39,580
+الحالة مقارنة الـ required reserve ريشيو 5% لأن
+
+14
+00:01:39,580 --> 00:01:41,960
+مقارنة الـ required reserve ريشيو 500% مقارنة الـ
+
+15
+00:01:41,960 --> 00:01:43,760
+required reserve ريشيو 500% مقارنة الـ required
+
+16
+00:01:43,760 --> 00:01:45,280
+reserve ريشيو 500% مقارنة الـ required reserve
+
+17
+00:01:45,280 --> 00:01:45,960
+ريشيو 500% مقارنة الـ required reserve ريشيو 500%
+
+18
+00:01:45,960 --> 00:01:50,800
+مقارنة الـ required reserve ريشيو 500% مقارنة الـ
+
+19
+00:01:50,800 --> 00:01:53,560
+required reserve ريشيو 500% مقارنة الـ required
+
+20
+00:01:53,560 --> 00:01:54,300
+reserve ريشيو 500% مقارنة الـ required reserve
+
+21
+00:01:54,300 --> 00:01:58,400
+ريشيو 500% مقارنة الـ required reserve ريشيو 500%
+
+22
+00:01:58,400 --> 00:02:00,140
+مقارنة الـ required reserve ريشيو 500% مقارنة الـ
+
+23
+00:02:00,140 --> 00:02:05,350
+required reserve ريشيو 500لذلك في هذه الحالة،
+
+24
+00:02:05,350 --> 00:02:14,610
+البنك الرئيسي يمكن أن يدفع 95 ألف دولار، وهو
+
+25
+00:02:14,610 --> 00:02:25,690
+المساعدات، فإن البنك الرئيسي يدفع هذه المساعدة إلى
+
+26
+00:02:27,670 --> 00:02:31,810
+علي to someone else suppose his name is علي right
+
+27
+00:02:31,810 --> 00:02:36,670
+علي receive this amount which is ninety five
+
+28
+00:02:36,670 --> 00:02:42,490
+thousand dollars and deposit it at the bank number
+
+29
+00:02:42,490 --> 00:02:47,150
+two suppose this is the bank of palestine this is
+
+30
+00:02:47,150 --> 00:02:51,890
+the arab bank so
+
+31
+00:02:51,890 --> 00:02:59,450
+عليأخذ المال من 95 ألف شخص لألف دولار و انتقل عليه
+
+32
+00:02:59,450 --> 00:03:04,080
+و بعدها تدفع هذا المال إلى عرب بنك العربلذلك نحن
+
+33
+00:03:04,080 --> 00:03:09,860
+لدينا مقاومة أو مقاومة جديدة في البنك العربي بقيمة
+
+34
+00:03:09,860 --> 00:03:16,280
+95 ألف دولار، صحيح؟ البنك العربي في هذه الحالة يجب
+
+35
+00:03:16,280 --> 00:03:21,580
+أن يقوم باستخدام 5% كمقاومة مطلوبة ويقوم بمقاومته
+
+36
+00:03:21,580 --> 00:03:24,780
+في الشركة الأساسية أو الحكومة المالية الفلسطينية
+
+37
+00:03:35,790 --> 00:03:44,630
+العربية يمكنها أن تدفع 90250$ كدفع لشركة عربية اذا
+
+38
+00:03:44,630 --> 00:03:54,340
+كان شخص اخر مثلا السيد أحمدboast this money or
+
+39
+00:03:54,340 --> 00:03:58,620
+both this money تمام this amount and deposit it in
+
+40
+00:03:58,620 --> 00:04:01,120
+the bank number three suppose it was the
+
+41
+00:04:01,120 --> 00:04:02,140
+agriculture bank
+
+42
+00:04:06,860 --> 00:04:11,440
+لذلك نحن لدينا مصادر جديدة في البنك التجاري يجب أن
+
+43
+00:04:11,440 --> 00:04:17,880
+يقطع 5% من هذا المقال كمية محتاجة للبنك التجاري و
+
+44
+00:04:17,880 --> 00:04:21,500
+بعدها يمكنه أن يدفع هذا المقال إلى هذا المقال
+
+45
+00:04:21,500 --> 00:04:28,360
+وكذلك لذلك لدينا أيضًا مرتبط أو تفتح في مصادر
+
+46
+00:04:28,360 --> 00:04:31,400
+المال ، لذلك مصادر المال في هذه الحالة
+
+47
+00:04:36,710 --> 00:04:44,850
+أو 100 ألف فقط لازم تزيد من 100 ألف أكتر من 100
+
+48
+00:04:44,850 --> 00:04:44,910
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+49
+00:04:44,910 --> 00:04:49,450
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+50
+00:04:49,450 --> 00:04:50,830
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+51
+00:04:50,830 --> 00:04:50,850
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+52
+00:04:50,850 --> 00:04:53,290
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+53
+00:04:53,290 --> 00:04:59,780
+أكتر من 100 أكتمثلًا، في هذه الحالة، يتم تخلص
+
+54
+00:04:59,780 --> 00:05:03,980
+المال أو يتم تخلص المال أو يتم تخلص المال أو يتم
+
+55
+00:05:03,980 --> 00:05:07,280
+تخلص المال أو يتم تخلص المال أو يتم تخلص المال أو
+
+56
+00:05:07,280 --> 00:05:07,360
+يتم تخلص المال أو يتم تخلص المال أو يتم تخلص المال
+
+57
+00:05:07,360 --> 00:05:07,660
+أو يتم تخلص المال أو يتم تخلص المال أو يتم تخلص
+
+58
+00:05:07,660 --> 00:05:08,920
+المال أو يتم تخلص المال أو يتم تخلص المال أو يتم
+
+59
+00:05:08,920 --> 00:05:10,240
+تخلص المال أو يتم تخلص المال أو يتم تخلص المال أو
+
+60
+00:05:10,240 --> 00:05:12,780
+يتم تخلص المال أو يتم تخلص المال أو يتم تخلص المال
+
+61
+00:05:12,780 --> 00:05:15,540
+أو يتم تخلص المال أو يتم تخلص المال أو يتم تخلص
+
+62
+00:05:15,540 --> 00:05:21,370
+المال أو يتم تخلربما يكون مشابه لـ Investment
+
+63
+00:05:21,370 --> 00:05:23,770
+Multiplier وGovernment Spending Multiplier إذا
+
+64
+00:05:23,770 --> 00:05:26,650
+تذكر أن الـ Government Spending Multiplier إذا
+
+65
+00:05:26,650 --> 00:05:31,610
+أزداد الحكومة بقيمة 100 ألف دولار، فإن نتيجة
+
+66
+00:05:31,610 --> 00:05:33,830
+النتيجة الأخيرة أو الأزداد الأخيرة في الـ
+
+67
+00:05:33,830 --> 00:05:36,750
+Aggregate Output أو الـ Aggregate Income ستزداد
+
+68
+00:05:36,750 --> 00:05:41,470
+بقيمة أكتر من 100 ألف دولار، فهو يعتمد على قيمة
+
+69
+00:05:41,470 --> 00:05:44,550
+الـ Margin of Propensity لتخزينها أو لإنقاذها، صح؟
+
+70
+00:05:45,630 --> 00:05:53,250
+مع نفس الفكرة هنا في هذه الحالة لدينا شيء
+
+71
+00:05:53,250 --> 00:06:00,730
+يسمى المال مرتبط مال مرتبط
+
+72
+00:06:00,730 --> 00:06:04,710
+مال مرتبط مال مرتبط مال مرتبط مال مرتبط مال مرتبط
+
+73
+00:06:04,710 --> 00:06:08,190
+مال مرتبط مال مرتبط مال مرتبط مال مرتبط مال مرتبط
+
+74
+00:06:14,610 --> 00:06:22,790
+مع المستحيل المستحيل المستحيل المستحيل
+
+75
+00:06:22,790 --> 00:06:27,130
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+76
+00:06:27,130 --> 00:06:27,310
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+77
+00:06:27,310 --> 00:06:27,330
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+78
+00:06:27,330 --> 00:06:27,430
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+79
+00:06:27,430 --> 00:06:28,710
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+80
+00:06:28,710 --> 00:06:30,930
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+81
+00:06:30,930 --> 00:06:31,810
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+82
+00:06:31,810 --> 00:06:32,050
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+83
+00:06:32,050 --> 00:06:33,510
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+84
+00:06:33,510 --> 00:06:41,910
+المستحيل المست
+
+85
+00:06:43,410 --> 00:06:50,850
+إذا كانت المصادر الأولى أو المصادر الأولى أو
+
+86
+00:06:50,850 --> 00:06:57,290
+المصادر الأولى كانت أو كانت أكتر من 100 ألف دولار،
+
+87
+00:06:57,290 --> 00:07:03,550
+فإن مصادر المال كانت تتطور إلى 20 مرة من هذا
+
+88
+00:07:03,550 --> 00:07:07,670
+المقاليعني لو واحد حط ميت ألف دولار ك initial
+
+89
+00:07:07,670 --> 00:07:11,570
+deposit كوديعة أصلية ال money supply would expand
+
+90
+00:07:11,570 --> 00:07:16,910
+هيتوسع ال money supply بعشرين ضعف المبلغ هذا so
+
+91
+00:07:16,910 --> 00:07:27,650
+the money supply money supply would increase would
+
+92
+00:07:27,650 --> 00:07:37,820
+expand to how muchالوديعة الأصلية مرة المالي
+
+93
+00:07:37,820 --> 00:07:49,440
+ملتبلير الوديعة
+
+94
+00:07:49,440 --> 00:07:59,040
+الأصلية مرة المالي ملتبلير الوديعة
+
+95
+00:07:59,040 --> 00:08:03,360
+الأصلية مرة المالي ملتبلير في هذه الحالةالدفع
+
+96
+00:08:03,360 --> 00:08:09,920
+المالي ستتطلع إلى كم؟ الدفع الأول هو 100 ألف
+
+97
+00:08:09,920 --> 00:08:13,780
+دولار، صحيح؟
+
+98
+00:08:13,780 --> 00:08:23,220
+المرة المالية المتعددة، وهو 20 مليون دولار فالدفع
+
+99
+00:08:23,220 --> 00:08:27,000
+المالي ستتطلع إلى 2 مليون دولار
+
+100
+00:08:34,370 --> 00:08:42,470
+USD واضحة ولا مش واضحة مين قايده طيب شباب اه okay
+
+101
+00:08:42,470 --> 00:08:47,870
+as we mentioned that if someone deposit one
+
+102
+00:08:47,870 --> 00:08:50,910
+hundred thousand dollar the value of money supply
+
+103
+00:08:50,910 --> 00:08:53,930
+would expand to not only by one hundred thousand
+
+104
+00:08:53,930 --> 00:08:58,490
+dollar it would expand by more than amount by the
+
+105
+00:08:58,490 --> 00:09:01,370
+value of multiplier right the money multiplier
+
+106
+00:09:01,990 --> 00:09:07,250
+الفرمولة التي تستخدمها لتخطيط اتفاق المال هو
+
+107
+00:09:07,250 --> 00:09:12,210
+الوديعة
+
+108
+00:09:12,210 --> 00:09:16,450
+الأصلية الوديعة الأصلية هي 100000 درهم مرتبط المال
+
+109
+00:09:18,190 --> 00:09:21,330
+مضروبة في قيمة المضاعف المضاعف النقود which equals
+
+110
+00:09:21,330 --> 00:09:24,370
+how much is the initial deposit one hundred
+
+111
+00:09:24,370 --> 00:09:27,970
+thousand dollar and the money multiplier as you
+
+112
+00:09:27,970 --> 00:09:31,770
+see equals twenty so one hundred thousand times
+
+113
+00:09:31,770 --> 00:09:36,690
+twenty equals two million حصل
+
+114
+00:09:36,690 --> 00:09:44,330
+ضرب عادي تمام okay so let's go to the exercise and
+
+115
+00:09:44,330 --> 00:09:44,850
+complete
+
+116
+00:09:48,230 --> 00:09:54,370
+الفكرة لذلك دعونا
+
+117
+00:09:54,370 --> 00:10:04,070
+نعود او حسنا تكمل المسألة كما ترى لدينا المعلومات
+
+118
+00:10:04,070 --> 00:10:10,170
+التالية عن الاقتصاد والأسئلة هي ما هو مقاومة
+
+119
+00:10:10,170 --> 00:10:13,630
+المساعدة بالضبط مقاومة المساعدة
+
+120
+00:10:16,680 --> 00:10:19,360
+مقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+121
+00:10:19,360 --> 00:10:21,120
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+122
+00:10:21,120 --> 00:10:26,520
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+123
+00:10:26,520 --> 00:10:34,640
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+124
+00:10:34,640 --> 00:10:38,780
+بالمقارنة
+
+125
+00:10:38,780 --> 00:10:45,680
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+126
+00:10:46,310 --> 00:10:55,350
+ماذا بعد ذلك؟ لذلك يقل إلى 5% تفرح للسيناريو ماذا
+
+127
+00:10:55,350 --> 00:11:00,190
+هو المعدل المالي في هذه الاقتصاد؟ المعدل المالي
+
+128
+00:11:00,190 --> 00:11:05,010
+يقل 1 عشان مقارنة المعدل المالي والذي يقل 20
+
+129
+00:11:05,010 --> 00:11:09,650
+مقارنة، صحيح؟ ماذا بعد ذلك؟ تفرح للسيناريو تبقى
+
+130
+00:11:09,650 --> 00:11:17,830
+على الأولى 100 ألف دولار كدفعالدولة المالية ستتطور
+
+131
+00:11:17,830 --> 00:11:22,790
+إلى كم؟ هذا هو السؤال، لذلك لدينا تطور في الدولة
+
+132
+00:11:22,790 --> 00:11:28,590
+المالية باستخدام الانتجارات الأولى المالية المزيد
+
+133
+00:11:28,590 --> 00:11:29,570
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+134
+00:11:29,570 --> 00:11:30,270
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+135
+00:11:30,270 --> 00:11:30,790
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+136
+00:11:30,790 --> 00:11:30,990
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+137
+00:11:30,990 --> 00:11:31,810
+من المزيد من
+
+138
+00:11:39,270 --> 00:11:42,750
+السيناريو إذا تغيّر مقاومة الحصول على مقاومة
+
+139
+00:11:42,750 --> 00:11:43,550
+الحصول على مقاومة الحصول على مقاومة الحصول على
+
+140
+00:11:43,550 --> 00:11:46,510
+مقاومة الحصول على مقاومة الحصول على مقاومة الحصول
+
+141
+00:11:46,510 --> 00:11:50,230
+على مقاومة الحصول على مقاومة الحصول على مقاومة
+
+142
+00:11:50,230 --> 00:11:50,250
+الحصول على مقاومة الحصول على مقاومة الحصول على
+
+143
+00:11:50,250 --> 00:11:53,970
+مقاومة الحصول على مقاومة الحصول على مقاومة الحصول
+
+144
+00:11:53,970 --> 00:11:56,390
+على مقاومة الحصول على مقاومة الحصول على مقاومة
+
+145
+00:11:56,390 --> 00:11:57,650
+الحصول على مقاومة الحصول على مقاومة الحصول على
+
+146
+00:11:57,650 --> 00:12:05,230
+مقاومة الحصول على مقاومة الحصول على مقاومة الحصول
+
+147
+00:12:05,230 --> 00:12:11,220
+على مقاومالرقم المطلوب يتغير من كم إلى 10% إذا
+
+148
+00:12:11,220 --> 00:12:16,360
+كداش في عندي أنا رقم المطلوب 10% يجب أن يتم تطبيقه
+
+149
+00:12:16,360 --> 00:12:20,360
+في كل البنوك، صح؟ هذا بتطبق على كل بنوك، ففي
+
+150
+00:12:20,360 --> 00:12:25,720
+الحالة الأولى، يجب أن يكون 10 ألف دولار في البنك
+
+151
+00:12:25,720 --> 00:12:30,180
+الأولى، صح؟ ففي هذه الحالة، يجب أن يكون العمول 90
+
+152
+00:12:30,180 --> 00:12:35,290
+ألف دولارلأ because the initial deposit كده؟ one
+
+153
+00:12:35,290 --> 00:12:38,970
+hundred thousand dollar أخدنا عشرة في المية as
+
+154
+00:12:38,970 --> 00:12:42,970
+required reserve عشرة تلاف كده؟ بيبقى تسعين ألف
+
+155
+00:12:42,970 --> 00:12:46,910
+تمام؟ تسعين ألف أجوا على البنك التاني so here we
+
+156
+00:12:46,910 --> 00:12:51,050
+have ninety thousand dollar right؟ كدهش منهم
+
+157
+00:12:51,050 --> 00:12:54,730
+required؟ عشرة في المية كدهش عشرة؟ تسعة تلاف
+
+158
+00:12:54,730 --> 00:12:58,210
+exactly nine thousand وبالتالي بيبقى عند ال loans
+
+159
+00:12:58,210 --> 00:13:03,890
+كده؟ واحد تمانين الف81000 درهم هذا اللي بيقدر
+
+160
+00:13:03,890 --> 00:13:08,750
+يعملهم lending البنك التاني صح حاضر شوف السؤال ايش
+
+161
+00:13:08,750 --> 00:13:12,390
+بيقول انه suppose ان ال required reserve ratio has
+
+162
+00:13:12,390 --> 00:13:16,470
+changed to 10% يعني بطل 5% ال required reserve
+
+163
+00:13:16,470 --> 00:13:21,910
+ratio تمام how much is the loan of the bank number
+
+164
+00:13:21,910 --> 00:13:26,970
+two اللي بيقدر يعملهم lendingوكما تعلمين، مقاومة
+
+165
+00:13:26,970 --> 00:13:30,210
+الـ required reserve ratio هي مقاومة على جميع
+
+166
+00:13:30,210 --> 00:13:35,930
+البنكين لأنها مقاومة على جميع البنكين لأنها مقاومة
+
+167
+00:13:35,930 --> 00:13:36,610
+لأنها مقاومة على جميع البنكين لأنها مقاومة على
+
+168
+00:13:36,610 --> 00:13:37,750
+جميع البنكين لأنها مقاومة على جميع البنكين لأنها
+
+169
+00:13:37,750 --> 00:13:40,010
+مقاومة على جميع البنكين لأنها مقاومة على جميع
+
+170
+00:13:40,010 --> 00:13:41,730
+البنكين لأنها مقاومة على جميع البنكين لأنها مقاومة
+
+171
+00:13:41,730 --> 00:13:43,110
+على جميع البنكين لأنها مقاومة على جميع البنكين
+
+172
+00:13:43,110 --> 00:13:45,890
+لأنها مقاومة على جميع البنكين ل
+
+173
+00:13:54,990 --> 00:13:57,330
+عشرة في المية عليهم break wild reserve كده، يش
+
+174
+00:13:57,330 --> 00:13:59,750
+بيصيروا عشر تلاف، وابتالي البنك الأول، the first
+
+175
+00:13:59,750 --> 00:14:02,650
+bank يداش بيعمل ال loans، تسعين ألف، تسعين ألف
+
+176
+00:14:02,650 --> 00:14:07,580
+أجوا as a deposit في البنك التانيعليهم 10% تسعة
+
+177
+00:14:07,580 --> 00:14:11,920
+تلاف تسعة تلاف كدهش تسعين ألف نقص تسعة تلاف واحد
+
+178
+00:14:11,920 --> 00:14:17,200
+تمانين ألف so we have loans by ninety thousand
+
+179
+00:14:17,200 --> 00:14:22,980
+dollars sorry eighty one thousand dollar right
+
+180
+00:14:22,980 --> 00:14:27,440
+واضحة الأمور ولا مش واضحة طيب so let's come back
+
+181
+00:14:27,440 --> 00:14:34,420
+to the idea and complete the exercises
+
+182
+00:14:47,150 --> 00:14:52,970
+بالتالي، كما ترى هنا في الوصفة، المرتبط المالي هو
+
+183
+00:14:52,970 --> 00:14:56,830
+المرتبط بمجموعة يمكن أن تزداد في كل دولار تزداد في
+
+184
+00:14:56,830 --> 00:14:57,530
+المحافظة
+
+185
+00:15:17,960 --> 00:15:22,320
+معظم المالي مالي مالي مالي مالي مالي مالي مالي
+
+186
+00:15:22,320 --> 00:15:23,120
+مالي مالي مالي مالي مالي مالي مالي مالي مالي مالي
+
+187
+00:15:23,120 --> 00:15:23,680
+مالي مالي مالي مالي مالي مالي مالي مالي مالي مالي
+
+188
+00:15:23,680 --> 00:15:24,360
+مالي مالي مالي مالي مالي مالي مالي مالي مالي مالي
+
+189
+00:15:24,360 --> 00:15:26,270
+مالي مالي مالي مالي مالي مإنه الـ money supply
+
+190
+00:15:26,270 --> 00:15:30,390
+would expand .. it would expand by five times of
+
+191
+00:15:30,390 --> 00:15:35,150
+the initial deposits، صح؟ هيضعف خمس مرات بمقدار
+
+192
+00:15:35,150 --> 00:15:38,790
+الوديعة الأصلية، مظبوط ولا لأ؟ صح؟ هذا ال idea
+
+193
+00:15:38,790 --> 00:15:43,090
+طبعاً، so let's go to this example as you see or
+
+194
+00:15:43,090 --> 00:15:46,330
+an exercise the required reserve ratio is suppose
+
+195
+00:15:46,330 --> 00:15:48,690
+that the required reserve ratio equals five
+
+196
+00:15:48,690 --> 00:15:53,210
+percent the money multiplier is how much؟ money
+
+197
+00:15:53,210 --> 00:15:58,110
+multiplierequals one over five percent equals
+
+198
+00:15:58,110 --> 00:16:03,230
+twenty صح طب لو ميعطيني ال money multiplier قدش ال
+
+199
+00:16:03,230 --> 00:16:06,910
+required reserve ratio يعني هذا السؤال in this
+
+200
+00:16:06,910 --> 00:16:11,090
+case the money multiplier is eight or equals eight
+
+201
+00:16:11,090 --> 00:16:15,470
+how much is the required reserve ratio ارفي
+
+202
+00:16:15,470 --> 00:16:18,670
+القانون اللي هو money multiplier equals one over
+
+203
+00:16:18,670 --> 00:16:26,510
+RRRمعنى الـ Multiplier يعني 8 اكتر اكتر 8 اكتر 8
+
+204
+00:16:26,510 --> 00:16:42,030
+اكتر 8 اكتر 8 اكتر 8 اكتر
+
+205
+00:16:44,750 --> 00:16:51,110
+0.8 تمانية في المية خلاص that's it الإجابة eighty
+
+206
+00:16:51,110 --> 00:16:59,550
+percent تمام طيب ليش حسابات واحد تقسيم تمانية قداش
+
+207
+00:16:59,550 --> 00:17:03,770
+على القالع على طول بيطلع بجزء اتناش و نص يمكن في
+
+208
+00:17:03,770 --> 00:17:09,750
+المية twelve point five صح طيب
+
+209
+00:17:14,320 --> 00:17:22,080
+الان دعونا نتكلم عن المشروعات ومشروع مركزي البنك
+
+210
+00:17:22,080 --> 00:17:22,860
+او مجلس المحافظة الوطنية
+
+211
+00:17:29,640 --> 00:17:35,400
+الشركة الرئيسية تلقى رولة مهمة في الاقتصاد ونحن
+
+212
+00:17:35,400 --> 00:17:42,340
+لدينا الاختصارات التالية لهذه الانستجرامة رقم واحد
+
+213
+00:17:42,340 --> 00:17:47,160
+اختيار ادخل مقاسات البنك موضوع المقاصة التعالج من
+
+214
+00:17:47,160 --> 00:17:50,760
+وين؟ في الشركة الرئيسية ماذا اخر؟ تحكم نظام البنك
+
+215
+00:17:50,760 --> 00:17:57,090
+من ينظم نظام البنك؟ الشركة الرئيسيةمساعدة الشركات
+
+216
+00:17:57,090 --> 00:18:02,330
+في موقعات مالية صعبة، على سبيل المثال، إحدى
+
+217
+00:18:02,330 --> 00:18:05,510
+الشركات تتعامل مع مشكلة، تتعامل مع مقاومة، في هذه
+
+218
+00:18:05,510 --> 00:18:08,210
+الحالة، يمكن الشركة الأساسية أن تدفع هذه الشركة
+
+219
+00:18:08,210 --> 00:18:15,240
+لتحل المصادرة المالية أو لتخلص من المقاومةwhat
+
+220
+00:18:15,240 --> 00:18:19,720
+else managing exchange rates طبعا من اللي بتحكي
+
+221
+00:18:19,720 --> 00:18:22,760
+بال exchange rate أسعار الصرف العملات وليه ال
+
+222
+00:18:22,760 --> 00:18:26,160
+central bank what is control the merges between
+
+223
+00:18:26,160 --> 00:18:29,660
+banks بنك بدي اندمج مع بنك تاني مين اللي بيعمل ال
+
+224
+00:18:29,660 --> 00:18:33,420
+organization لل organizing للعملية ال central bank
+
+225
+00:18:33,420 --> 00:18:39,380
+what else examination of the banks to ensure that
+
+226
+00:18:39,380 --> 00:18:43,840
+they are financially sound مش هيك على بنوك من شغله
+
+227
+00:18:43,840 --> 00:18:47,940
+صحأموره المالية سليمة عشان موضوع ال corruption و
+
+228
+00:18:47,940 --> 00:18:52,500
+اللي هي setting of reserves requirements for all
+
+229
+00:18:52,500 --> 00:18:54,540
+financial institutions الموضوع اللي required
+
+230
+00:18:54,540 --> 00:18:59,140
+reserve ratio اللي حكينا فيه مظبوط و the last
+
+231
+00:18:59,140 --> 00:19:03,400
+thing is lender of the last resort أخر ملاذ للبنو
+
+232
+00:19:03,400 --> 00:19:06,680
+كانت تقترض أو تحل مشاكلها المالية هو ال central
+
+233
+00:19:06,680 --> 00:19:08,580
+bank yes طبعا و ال money supply yes
+
+234
+00:19:12,180 --> 00:19:18,640
+هنا كما تشاهد انه يتكلم عن افعالية مقاومة المال
+
+235
+00:19:18,640 --> 00:19:26,160
+على مقاومة المال كمان كمان كمان كمان كمان كمان
+
+236
+00:19:26,160 --> 00:19:29,740
+كمان
+
+237
+00:19:29,740 --> 00:19:34,580
+كمان كمان كمان كمان كمان كمان كمان كمان كمان كمان
+
+238
+00:19:34,580 --> 00:19:34,800
+كمان كمان كمان كمان كمان كمان كمان كمان كمان كمان
+
+239
+00:19:34,800 --> 00:19:40,620
+كمان كمان كمان كمان كمان كمان كمان كمان كمانهناك
+
+240
+00:19:40,620 --> 00:19:42,900
+علاقة عكسية بين مقاومة المال والمقاومة المفترضة
+
+241
+00:19:42,900 --> 00:19:46,500
+والمقاومة
+
+242
+00:19:46,500 --> 00:19:48,160
+المفترضة والمقاومة المفترضة والمقاومة المفترضة
+
+243
+00:19:48,160 --> 00:19:52,600
+والمقاومة المفترضة والمقاومة المفترضة والمقاومة
+
+244
+00:19:52,600 --> 00:19:55,280
+المفترضة والمقاومة المفترضة والمقاومة المفترضة
+
+245
+00:19:55,280 --> 00:19:56,940
+والمقاومة المفترضة والمقاومة المفترضة والمقاومة
+
+246
+00:19:56,940 --> 00:19:56,960
+المفترضة والمقاومة المفترضة والمقاومة المفترضة
+
+247
+00:19:56,960 --> 00:19:59,280
+والمقاومة المفترضة والمقاومة المفترضة والمقاومة
+
+248
+00:19:59,280 --> 00:20:04,460
+المفترضة والمقاومة المفترضة والمقاومة
+
+249
+00:20:04,460 --> 00:20:04,580
+المف
+
+250
+00:20:10,560 --> 00:20:14,300
+وبالتالي ال capacity for the commercial banks to
+
+251
+00:20:14,300 --> 00:20:17,500
+lend أيش بتصير؟ تنزل يعني سببز أنه ال bank كان
+
+252
+00:20:17,500 --> 00:20:23,040
+بيطلب 20% على كل ودي ابتجيب صار يطلب 30% عامليا ال
+
+253
+00:20:23,040 --> 00:20:25,380
+money supply شو بيقل؟ ال reserves الاحتياط اللي
+
+254
+00:20:25,380 --> 00:20:28,840
+موجود عند البنوكة أيش بتصير فيها؟ بيقل وبالتالي ال
+
+255
+00:20:28,840 --> 00:20:34,780
+money supply would what؟ decline here
+
+256
+00:20:34,780 --> 00:20:39,740
+is the idea كل هذاexactly كل احتياط بيصير required
+
+257
+00:20:39,740 --> 00:20:42,600
+أو ال required reserve اللي بيروح على ال central
+
+258
+00:20:42,600 --> 00:20:46,060
+bank بده يزيد وبتالي ال excess excess reserves
+
+259
+00:20:46,060 --> 00:20:49,200
+اللي موجودة عند البنوك اشمالها بدها تقل وبتالي
+
+260
+00:20:49,200 --> 00:20:52,760
+their capacity to lend would decline and then the
+
+261
+00:20:52,760 --> 00:20:56,940
+money supply would decline as well صح؟ اظبط ولا
+
+262
+00:20:56,940 --> 00:21:03,820
+لأ؟ طيب هذه ال idea تبعت ال page هذا كلهالقيم
+
+263
+00:21:03,820 --> 00:21:08,560
+التجارية كما ذكرت قبل أن القيم التجارية هي القيم
+
+264
+00:21:08,560 --> 00:21:15,600
+الدفع اللي يدفعه البنك للمجلد عندما يدفعه منها لما
+
+265
+00:21:15,600 --> 00:21:17,880
+بيجي البنك التجارة بديه يقترض من البنك المركزي
+
+266
+00:21:17,880 --> 00:21:21,120
+لازم يدفع دفع دفع هو ده القيم التجارية اللي أخدنا
+
+267
+00:21:21,120 --> 00:21:27,200
+المرة الماضية وهناك علاقة عكسية أيضا بين القيم
+
+268
+00:21:27,200 --> 00:21:31,340
+التجارية ومال المدفع تزيد القيم التجارية
+
+269
+00:21:35,530 --> 00:21:43,650
+leads to increasing of the cost of borrowing of
+
+270
+00:21:43,650 --> 00:21:51,650
+the commercial banks from the central bank صح
+
+271
+00:21:51,650 --> 00:21:56,090
+القدرة تبعت عمليا ال cost of borrowing بيزيد
+
+272
+00:21:56,090 --> 00:22:04,990
+فبالتالي the capacity or the value or amount of
+
+273
+00:22:07,070 --> 00:22:11,670
+Borrowing شو بيصير فيها ده؟ و decline exactly؟
+
+274
+00:22:11,670 --> 00:22:16,410
+بتبطل ابنه بتقترض من البنك المركزي؟ this leads to
+
+275
+00:22:16,410 --> 00:22:22,850
+what؟ انه ال money supply و ال decline كمان ال
+
+276
+00:22:22,850 --> 00:22:28,270
+reserves عندهم أشمالها بتقل صح؟ مظبوط ولا لأ؟ so
+
+277
+00:22:28,270 --> 00:22:31,430
+in general there is an inverse relationship
+
+278
+00:22:31,430 --> 00:22:33,730
+between the required reserve ratio and money
+
+279
+00:22:33,730 --> 00:22:38,730
+supplyAlso inverse relationship between the
+
+280
+00:22:38,730 --> 00:22:40,730
+discount rate and money supply
+
+281
+00:23:16,510 --> 00:23:18,990
+لنذهب الى عملية عملية عملية عملية عملية عملية
+
+282
+00:23:18,990 --> 00:23:22,170
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+283
+00:23:22,170 --> 00:23:22,210
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+284
+00:23:22,210 --> 00:23:24,090
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+285
+00:23:24,090 --> 00:23:24,170
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+286
+00:23:24,170 --> 00:23:26,610
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+287
+00:23:26,610 --> 00:23:29,450
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+288
+00:23:29,450 --> 00:23:34,810
+عملية عملية عملوالحماية الحكومية بشتري أو ببيع
+
+289
+00:23:34,810 --> 00:23:39,570
+حملة حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+290
+00:23:39,570 --> 00:23:43,090
+حملة حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+291
+00:23:43,090 --> 00:23:44,850
+حملة حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+292
+00:23:44,850 --> 00:23:45,270
+حملة حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+293
+00:23:45,270 --> 00:23:45,310
+حملة حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+294
+00:23:59,660 --> 00:24:11,340
+إذا كنت أرغب في إضافة المال إذا كنت
+
+295
+00:24:11,340 --> 00:24:13,840
+أرغب في إضافة المال إذا كنت أرغب في إضافة المال
+
+296
+00:24:13,840 --> 00:24:20,000
+إذا كنت أرغب في إضافة المال إذا كنت أرغب في إضافة
+
+297
+00:24:20,000 --> 00:24:20,620
+المال إذا كنت أرغب في إضافة المال إذا كنت أرغب في
+
+298
+00:24:20,620 --> 00:24:25,200
+إضافة المال إذا كنت أرغب في إضافة المال إذا كنت
+
+299
+00:24:25,200 --> 00:24:26,260
+أرغب في إضافة المال
+
+300
+00:24:28,580 --> 00:24:31,360
+هذه هي .. في هذه الحالة، ستزال تزال تزال تزال تزال
+
+301
+00:24:31,360 --> 00:24:31,820
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+302
+00:24:31,820 --> 00:24:39,100
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+303
+00:24:39,100 --> 00:24:39,740
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+304
+00:24:39,740 --> 00:24:39,780
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+305
+00:24:39,780 --> 00:24:40,660
+تزال تزال تزال تزال تزال تزال
+
+306
+00:24:47,780 --> 00:24:50,560
+صح؟ So in this case what would happen؟ The money
+
+307
+00:24:50,560 --> 00:24:54,260
+supply would increase and vice versa for sure when
+
+308
+00:24:54,260 --> 00:24:58,280
+the government or the central bank wants to
+
+309
+00:24:58,280 --> 00:25:02,140
+decrease the money supply If the government or the
+
+310
+00:25:02,140 --> 00:25:05,920
+central bank wants to decrease the money supply it
+
+311
+00:25:05,920 --> 00:25:11,360
+can what? borrow money or take money and give the
+
+312
+00:25:11,360 --> 00:25:17,310
+people government securities صح؟بس هي الفكرة صعبة؟
+
+313
+00:25:17,310 --> 00:25:20,530
+طبعا هذه أكتر الأدوات بيستخدمها ال central bank
+
+314
+00:25:20,530 --> 00:25:26,310
+لأنه مالهاش side effects لأن ال discount rate has
+
+315
+00:25:26,310 --> 00:25:30,630
+negative effects or has some effects on the
+
+316
+00:25:30,630 --> 00:25:32,990
+investment and on the interest rate and then
+
+317
+00:25:32,990 --> 00:25:38,210
+investmentبس ال purchasing and selling of the
+
+318
+00:25:38,210 --> 00:25:41,970
+government securities has less effects on the
+
+319
+00:25:41,970 --> 00:25:44,950
+economy or less negative effects on the economy
+
+320
+00:25:44,950 --> 00:25:50,290
+وبالتالي أكتر أداء بيستخدمها ال central bank تمام؟
+
+321
+00:25:50,290 --> 00:25:56,970
+طيب So
+
+322
+00:25:56,970 --> 00:26:02,120
+as you see in this statementan open market
+
+323
+00:26:02,120 --> 00:26:05,260
+purchases of securities by the federal results in
+
+324
+00:26:05,260 --> 00:26:10,540
+an increase in reserves شو اللي بيصير؟ لما بيشتروا
+
+325
+00:26:10,540 --> 00:26:13,780
+government securities و بيعطوا الناس مصارى، شو
+
+326
+00:26:13,780 --> 00:26:16,680
+اللي بيصير في ال reserves؟ أو بيعطيه للبنوك، شو
+
+327
+00:26:16,680 --> 00:26:20,520
+اللي بيصير في ال reserves؟ with increase، هايو ال
+
+328
+00:26:20,520 --> 00:26:23,160
+pricing، نحلله هيك
+
+329
+00:26:30,690 --> 00:26:37,810
+the purchasing of of
+
+330
+00:26:37,810 --> 00:26:43,050
+government securities اشترينا من الناس ورق شو
+
+331
+00:26:43,050 --> 00:26:47,210
+اعطيناهم money money this leads to شو بيعمل في ال
+
+332
+00:26:47,210 --> 00:26:49,290
+reserves الاحتياط اللي موجود عند الناس و ليه عند
+
+333
+00:26:49,290 --> 00:26:52,810
+البنوك exactly so this leads to increasing the
+
+334
+00:26:52,810 --> 00:26:58,670
+reserves and then ال money supply would increase
+
+335
+00:27:00,500 --> 00:27:07,140
+صح؟ طب يزيد بقداش؟ بقيمة ال money multiplier صح؟
+
+336
+00:27:07,140 --> 00:27:14,900
+مظبوط ولا لا؟ وهي الجملة هيك تمام؟ and vice versa
+
+337
+00:27:14,900 --> 00:27:20,320
+if the bank or the central bank sell or selling
+
+338
+00:27:20,320 --> 00:27:25,560
+the government of government securities leads to a
+
+339
+00:27:25,560 --> 00:27:32,840
+decreasing in reservesعلى البنك والعاملين وهو ما
+
+340
+00:27:32,840 --> 00:27:41,280
+يسبب في اتقال في مصادر المال بقنا
+
+341
+00:27:41,280 --> 00:27:45,200
+ورق للناس وخدنا منهم الفلوس شو صار فى مصادر المال
+
+342
+00:27:45,200 --> 00:27:52,360
+نزلت وبتالي المصادر المال نزلت اتقال صح؟ طبعا
+
+343
+00:27:52,360 --> 00:27:55,060
+بقيمة اللى هو ال money multiplier
+
+344
+00:27:59,750 --> 00:28:05,610
+بالتالي كما تشاهد، هذه هي الفائعات،
+
+345
+00:28:05,610 --> 00:28:13,890
+كما تشاهد، شركة اوبين ماركتoperations are the
+
+346
+00:28:13,890 --> 00:28:16,590
+federal preferred means of controlling the money
+
+347
+00:28:16,590 --> 00:28:20,330
+supply because طبعا البنك المركزي بيفضل أنه يستخدم
+
+348
+00:28:20,330 --> 00:28:23,930
+.. يستخدم ال open market operations يعني أكتر من
+
+349
+00:28:23,930 --> 00:28:27,070
+ال discount rate و ال required reserve ratio ليش؟
+
+350
+00:28:27,070 --> 00:28:30,590
+لأنه they can .. they can be used with some
+
+351
+00:28:30,590 --> 00:28:36,330
+precisions طبعا بدقة أكتر و فيه flexibility أنه
+
+352
+00:28:36,330 --> 00:28:42,340
+بيع و اشتري و هيك and fairly predictableطبعا موضوع
+
+353
+00:28:42,340 --> 00:28:48,580
+التنبؤ و ال .. let's go to the money supply and
+
+354
+00:28:48,580 --> 00:28:52,700
+money demand before going to this diagram or
+
+355
+00:28:52,700 --> 00:28:56,180
+figure let's analyze the relationship between the
+
+356
+00:28:56,180 --> 00:28:59,480
+money demand and money supply sorry and interest
+
+357
+00:28:59,480 --> 00:28:59,780
+rate
+
+358
+00:29:18,950 --> 00:29:23,970
+قيمة الدفع والمال
+
+359
+00:29:23,970 --> 00:29:28,770
+بشكل
+
+360
+00:29:28,770 --> 00:29:28,850
+عام
+
+361
+00:29:33,000 --> 00:29:37,620
+العرض النقد او المال المستخدم يتحرر او يقوم بتحريك
+
+362
+00:29:37,620 --> 00:29:40,740
+المال من مجلس البنك الرئيسي يعني بيجي البنك ويقولك
+
+363
+00:29:40,740 --> 00:29:44,160
+انا بدي العرض النقد بدنا نخليه 200 ألف دولار 200
+
+364
+00:29:44,160 --> 00:29:48,160
+مليون دولار مثلا تمام وبالتالي there is no
+
+365
+00:29:48,160 --> 00:29:51,300
+relationship between ال interest rate و ال money
+
+366
+00:29:51,300 --> 00:29:54,360
+supply انه زاد ال interest rate مابأثرش على ال
+
+367
+00:29:54,360 --> 00:29:57,320
+money supply because انه ال bank ال central bank
+
+368
+00:29:57,320 --> 00:30:00,200
+هو بيحدد انه عرض النقد بيكون عندنا 200 مليون وخلاص
+
+369
+00:30:00,200 --> 00:30:05,100
+مالوش دعوةإنه the interest rate has no effects on
+
+370
+00:30:05,100 --> 00:30:08,340
+the money supply لأنه البنك هو اللي بيحدد it so we
+
+371
+00:30:08,340 --> 00:30:14,200
+will see that the money supply is a vertical line
+
+372
+00:30:14,200 --> 00:30:19,400
+هذا we are talking about the money market هدف ال
+
+373
+00:30:19,400 --> 00:30:23,010
+money marketفي عندى طلب على النقود money demand
+
+374
+00:30:23,010 --> 00:30:26,570
+وفي money supply زى ال goods and services market
+
+375
+00:30:26,570 --> 00:30:30,530
+في عندى طلب على السلع وفي عرض للسلع فى ال labor
+
+376
+00:30:30,530 --> 00:30:34,110
+market فى عندى labor demand و labor supply فى ال
+
+377
+00:30:34,110 --> 00:30:39,450
+money market عندى money demand و money supply طبعا
+
+378
+00:30:39,450 --> 00:30:44,340
+ال money supply in general is a vertical lineهي
+
+379
+00:30:44,340 --> 00:30:49,620
+تقرية تعني أنه لا يوجد علاقة ما بين قيمة الدولة
+
+380
+00:30:49,620 --> 00:30:55,540
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+381
+00:30:55,540 --> 00:30:55,620
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+382
+00:30:55,620 --> 00:30:58,380
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+383
+00:30:58,380 --> 00:31:00,640
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+384
+00:31:00,640 --> 00:31:05,640
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+385
+00:31:05,640 --> 00:31:09,660
+والدولة
+
+386
+00:31:09,660 --> 00:31:18,230
+والدوصار 6% بماني سابلاي او a بي ال quant of money
+
+387
+00:31:18,230 --> 00:31:24,030
+supplied would not change كونستان طب شو هو ال
+
+388
+00:31:24,030 --> 00:31:29,650
+interest rate بالمناسبة يعني تكلفة الاقتراض لأنه
+
+389
+00:31:29,650 --> 00:31:32,810
+suppose الفاعدة suppose that I would like to
+
+390
+00:31:32,810 --> 00:31:37,360
+withdraw a loan from the bankبيقول في عليك
+
+391
+00:31:37,360 --> 00:31:41,300
+interest خمسة في المية، عبارة عن إيش هاي؟ cost of
+
+392
+00:31:41,300 --> 00:31:49,820
+borrowing، مظبوط؟ هي تكلفة اقتراض، تمام؟ طيب لأ،
+
+393
+00:31:49,820 --> 00:31:55,400
+in general كله، in general يعني نظره من الوراق
+
+394
+00:31:55,400 --> 00:32:00,940
+حالة ما هو عبارة عن تكلفة اقتراض بروالأ لأ لأ
+
+395
+00:32:00,940 --> 00:32:03,640
+النظام الإسلامي بيبقى مشترق I was working as a
+
+396
+00:32:03,640 --> 00:32:08,380
+manager of the مرابحة system of the Islamic relief
+
+397
+00:32:08,380 --> 00:32:14,360
+six years ago the مرابحة system is completely
+
+398
+00:32:14,360 --> 00:32:21,000
+different from the commercial banks under the
+
+399
+00:32:21,000 --> 00:32:21,800
+مرابحة system
+
+400
+00:32:25,010 --> 00:32:33,650
+أو الناس اللي يريدون الهجوم يقوم بشراء سيارة و
+
+401
+00:32:33,650 --> 00:32:41,490
+يقوم بزيارة المجتمع اللي اعطاه المرابحة
+
+402
+00:32:53,720 --> 00:32:58,600
+في هذه الحالة، يمكن الاسلاميين أن يشتري السيارة
+
+403
+00:32:58,600 --> 00:33:07,580
+ويشتريها ومن ثم يقومون بتسليعها للشركة أو الشخص
+
+404
+00:33:07,580 --> 00:33:18,070
+الذي يريد التسليع بمعنى 5600$نعم، لتدفع المال
+
+405
+00:33:18,070 --> 00:33:23,410
+كإدارة حسنا، كما ترى، لذلك كما ذكرنا أن الدولة هي
+
+406
+00:33:23,410 --> 00:33:28,010
+محطة التدفع، صحيح؟ ومعظم المال، المعظم المعظم
+
+407
+00:33:28,010 --> 00:33:28,510
+المعظم المعظم المعظم المعظم المعظم المعظم المعظم
+
+408
+00:33:28,510 --> 00:33:29,570
+المعظم المعظم المعظم المعظم المعظم المعظم المعظم
+
+409
+00:33:29,570 --> 00:33:31,910
+المعظم المعظم المعظم المعظم المعظم المعظم المعظم
+
+410
+00:33:31,910 --> 00:33:34,870
+المعظم المعظم المعظم المعظم المعظم المعظم المعظم
+
+411
+00:33:34,870 --> 00:33:36,170
+المعظم المعظم المعظم المعظم المعظم المعظم المعظم
+
+412
+00:33:36,170 --> 00:33:40,790
+المعظم المعظم
+
+413
+00:33:40,790 --> 00:33:46,390
+المعظم المعظم
+
+414
+00:33:46,410 --> 00:33:50,870
+in the economy خلاص هي هيك so there is no
+
+415
+00:33:50,870 --> 00:33:55,610
+relationship between the interest rate on or there
+
+416
+00:33:55,610 --> 00:34:00,110
+is no effect of the interest rate on the quantity
+
+417
+00:34:00,110 --> 00:34:05,270
+of money supplied تمام؟ طيب what about the
+
+418
+00:34:05,270 --> 00:34:08,430
+relationship between the interest rate and money
+
+419
+00:34:08,430 --> 00:34:16,960
+demand suppose thatالقيمة أزالت، هذا يعني أن قيمة
+
+420
+00:34:16,960 --> 00:34:21,420
+التخزين أزالت، صح؟ شو بيصير في ال quantum money
+
+421
+00:34:21,420 --> 00:34:26,160
+demand؟ بده ينزل، صح؟ بالضبط، لأن قيمة التخزين
+
+422
+00:34:26,160 --> 00:34:32,920
+ستزال، صح ولا لأ؟ لذا دعونا نشرح العلاقة بين ال
+
+423
+00:34:32,920 --> 00:34:36,520
+money demand أو ال quantum money demanded وقيمة
+
+424
+00:34:42,910 --> 00:34:49,370
+I means interest rate or R sometimes R interest
+
+425
+00:34:49,370 --> 00:34:52,010
+rate and this is the quantity of money demand
+
+426
+00:34:52,010 --> 00:34:56,990
+there
+
+427
+00:34:56,990 --> 00:35:00,190
+is an inverse relationship between the interest
+
+428
+00:35:00,190 --> 00:35:03,030
+rate and the quantity of money demand this is the
+
+429
+00:35:03,030 --> 00:35:08,770
+money demand curve الناس
+
+430
+00:35:08,770 --> 00:35:09,990
+ليش بتطلب المساري؟
+
+431
+00:35:13,680 --> 00:35:18,400
+عشان يشتري او يعمل speculation مضاربة
+
+432
+00:35:26,570 --> 00:35:29,850
+شو بتساوي في الـ quantity demanded for money for
+
+433
+00:35:29,850 --> 00:35:34,250
+speculation or for transaction؟ و ال decline صح
+
+434
+00:35:34,250 --> 00:35:37,130
+لأن ال cost of borrowing بزيد so the increasing of
+
+435
+00:35:37,130 --> 00:35:40,930
+interest rate leads to increasing the cost of
+
+436
+00:35:40,930 --> 00:35:45,850
+borrowing then
+
+437
+00:35:45,850 --> 00:35:51,050
+the amount or the quantity demanded for money
+
+438
+00:35:54,660 --> 00:35:58,880
+تتخلص من السبب في التحديات والتعامل بالتعامل
+
+439
+00:35:58,880 --> 00:36:00,260
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+440
+00:36:00,260 --> 00:36:02,480
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+441
+00:36:02,480 --> 00:36:04,000
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+442
+00:36:04,000 --> 00:36:05,240
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+443
+00:36:05,240 --> 00:36:05,980
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+444
+00:36:05,980 --> 00:36:06,220
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+445
+00:36:06,220 --> 00:36:06,560
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+446
+00:36:06,560 --> 00:36:16,100
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+447
+00:36:20,600 --> 00:36:28,660
+و Q Money Demand 1 وهذا هو نقطة A انزعاج انترنت من
+
+448
+00:36:28,660 --> 00:36:38,180
+R1 إلى R2 من 5% إلى 10% أو 7% هذا يعيد إلى اقل من
+
+449
+00:36:38,180 --> 00:36:39,340
+المال المطالب
+
+450
+00:36:43,150 --> 00:36:48,990
+هذا هو النقطة B لذلك حركة الأموال والدماء هي تنقل
+
+451
+00:36:48,990 --> 00:36:56,010
+من اليسار إلى اليسار بالنسبة للعاملين كما تعلمون
+
+452
+00:36:56,010 --> 00:37:03,630
+أن في كل السوق يوجد ايقاليبريام في السوق الخاص
+
+453
+00:37:03,630 --> 00:37:11,070
+بالأموال والدماء ايقاليبريام
+
+454
+00:37:11,070 --> 00:37:15,380
+يحدثبالضبط، كمية المال المطلوبة من الأشياء
+
+455
+00:37:15,380 --> 00:37:16,760
+المطلوبة من الأشياء المطلوبة من الأشياء المطلوبة
+
+456
+00:37:16,760 --> 00:37:18,000
+من الأشياء المطلوبة من الأشياء المطلوبة من الأشياء
+
+457
+00:37:18,000 --> 00:37:19,240
+المطلوبة من الأشياء المطلوبة من الأشياء المطلوبة
+
+458
+00:37:19,240 --> 00:37:20,200
+من الأشياء المطلوبة من الأشياء المطلوبة من الأشياء
+
+459
+00:37:20,200 --> 00:37:20,840
+المطلوبة من الأشياء المطلوبة من الأشياء المطلوبة
+
+460
+00:37:20,840 --> 00:37:23,020
+من الأشياء المطلوبة من الأشياء المطلوبة من الأشياء
+
+461
+00:37:23,020 --> 00:37:23,360
+المطلوبة من الأشياء المطلوبة من الأشياء المطلوبة
+
+462
+00:37:23,360 --> 00:37:27,920
+من الأشياء المطلوبة من الأشياء المطلوبة من الأشياء
+
+463
+00:37:27,920 --> 00:37:31,530
+المطلفي كل السوق في السوق الخدمات والسوق العملي
+
+464
+00:37:31,530 --> 00:37:36,910
+وفي السوق المالي ، لذلك الانتقال في السوق المالي
+
+465
+00:37:36,910 --> 00:37:42,130
+يحدث عندما التطبيق المالي يتجاوز مع المصادر
+
+466
+00:37:42,130 --> 00:37:44,570
+المالية ، لذلك اعتمدي أن هذا هو المصادر المالية ،
+
+467
+00:37:44,570 --> 00:37:50,560
+أين هو الانتقال في نقطة A؟The money demand
+
+468
+00:37:50,560 --> 00:37:55,380
+intersects the money supply، this is our .. here
+
+469
+00:37:55,380 --> 00:38:00,200
+we have an equilibrium in the money market تمام؟
+
+470
+00:38:00,200 --> 00:38:02,500
+لسه المرة اللي جايب نكمل يعطيكم الأعافية شوية
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/SRYAT9ODXjs_raw.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/SRYAT9ODXjs_raw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..44d461770d80e4022317749da157c5a44c83e172
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/SRYAT9ODXjs_raw.srt
@@ -0,0 +1,1968 @@
+1
+00:00:20,700 --> 00:00:24,500
+اليوم ان شاء الله سنكمل الحلقة السادسة، Money
+
+2
+00:00:24,500 --> 00:00:30,380
+Supply و Federal Reserve System في هذه الدراسة،
+
+3
+00:00:30,380 --> 00:00:34,620
+سنركز على الـ Money Multiplier و الأدوات المختلفة
+
+4
+00:00:34,620 --> 00:00:36,860
+التي يستخدمها الشركة الرئيسية أو Federal Reserve
+
+5
+00:00:36,860 --> 00:00:44,180
+System لتحكم مصادر الماللتفهم المصطلح المالي مالتي
+
+6
+00:00:44,180 --> 00:00:49,000
+بلاير دعنا نأخذ المثال التالف لكي نفهم المصطلح
+
+7
+00:00:49,000 --> 00:00:57,480
+والفكرة، فاعترض ان بعض منكم لديه 100 ألف دولار
+
+8
+00:00:57,480 --> 00:01:07,090
+فاعترض ان محمد لديه 100 ألف دولاروهي تدفع هذه
+
+9
+00:01:07,090 --> 00:01:13,830
+المقاومة لبنك فلسطين بنك واحد بنك رقم واحد كدفعة
+
+10
+00:01:13,830 --> 00:01:20,270
+جديدة في هذه الحالة البنك الرئيسي أو بنك واحد بنك
+
+11
+00:01:20,270 --> 00:01:27,590
+رقم واحد يجب أن يدفع المقاومة المطلوبة ويدفعها
+
+12
+00:01:27,590 --> 00:01:35,160
+كمقاومة في بنك الرئيسي صح؟بالنسبة لـ 5000$ ففي هذه
+
+13
+00:01:35,160 --> 00:01:39,580
+الحالة مقارنة الـ required reserve ريشيو 5% لأن
+
+14
+00:01:39,580 --> 00:01:41,960
+مقارنة الـ required reserve ريشيو 500% مقارنة الـ
+
+15
+00:01:41,960 --> 00:01:43,760
+required reserve ريشيو 500% مقارنة الـ required
+
+16
+00:01:43,760 --> 00:01:45,280
+reserve ريشيو 500% مقارنة الـ required reserve
+
+17
+00:01:45,280 --> 00:01:45,960
+ريشيو 500% مقارنة الـ required reserve ريشيو 500%
+
+18
+00:01:45,960 --> 00:01:50,800
+مقارنة الـ required reserve ريشيو 500% مقارنة الـ
+
+19
+00:01:50,800 --> 00:01:53,560
+required reserve ريشيو 500% مقارنة الـ required
+
+20
+00:01:53,560 --> 00:01:54,300
+reserve ريشيو 500% مقارنة الـ required reserve
+
+21
+00:01:54,300 --> 00:01:58,400
+ريشيو 500% مقارنة الـ required reserve ريشيو 500%
+
+22
+00:01:58,400 --> 00:02:00,140
+مقارنة الـ required reserve ريشيو 500% مقارنة الـ
+
+23
+00:02:00,140 --> 00:02:05,350
+required reserve ريشيو 500لذلك في هذه الحالة،
+
+24
+00:02:05,350 --> 00:02:14,610
+البنك الرئيسي يمكن أن يدفع 95 ألف دولار، وهو
+
+25
+00:02:14,610 --> 00:02:25,690
+المساعدات، فإن البنك الرئيسي يدفع هذه المساعدة إلى
+
+26
+00:02:27,670 --> 00:02:31,810
+علي to someone else suppose his name is علي right
+
+27
+00:02:31,810 --> 00:02:36,670
+علي receive this amount which is ninety five
+
+28
+00:02:36,670 --> 00:02:42,490
+thousand dollars and deposit it at the bank number
+
+29
+00:02:42,490 --> 00:02:47,150
+two suppose this is the bank of palestine this is
+
+30
+00:02:47,150 --> 00:02:51,890
+the arab bank so
+
+31
+00:02:51,890 --> 00:02:59,450
+عليأخذ المال من 95 ألف شخص لألف دولار و انتقل عليه
+
+32
+00:02:59,450 --> 00:03:04,080
+و بعدها تدفع هذا المال إلى عرب بنك العربلذلك نحن
+
+33
+00:03:04,080 --> 00:03:09,860
+لدينا مقاومة أو مقاومة جديدة في البنك العربي بقيمة
+
+34
+00:03:09,860 --> 00:03:16,280
+95 ألف دولار، صحيح؟ البنك العربي في هذه الحالة يجب
+
+35
+00:03:16,280 --> 00:03:21,580
+أن يقوم باستخدام 5% كمقاومة مطلوبة ويقوم بمقاومته
+
+36
+00:03:21,580 --> 00:03:24,780
+في الشركة الأساسية أو الحكومة المالية الفلسطينية
+
+37
+00:03:35,790 --> 00:03:44,630
+العربية يمكنها أن تدفع 90250$ كدفع لشركة عربية اذا
+
+38
+00:03:44,630 --> 00:03:54,340
+كان شخص اخر مثلا السيد أحمدboast this money or
+
+39
+00:03:54,340 --> 00:03:58,620
+both this money تمام this amount and deposit it in
+
+40
+00:03:58,620 --> 00:04:01,120
+the bank number three suppose it was the
+
+41
+00:04:01,120 --> 00:04:02,140
+agriculture bank
+
+42
+00:04:06,860 --> 00:04:11,440
+لذلك نحن لدينا مصادر جديدة في البنك التجاري يجب أن
+
+43
+00:04:11,440 --> 00:04:17,880
+يقطع 5% من هذا المقال كمية محتاجة للبنك التجاري و
+
+44
+00:04:17,880 --> 00:04:21,500
+بعدها يمكنه أن يدفع هذا المقال إلى هذا المقال
+
+45
+00:04:21,500 --> 00:04:28,360
+وكذلك لذلك لدينا أيضًا مرتبط أو تفتح في مصادر
+
+46
+00:04:28,360 --> 00:04:31,400
+المال ، لذلك مصادر المال في هذه الحالة
+
+47
+00:04:36,710 --> 00:04:44,850
+أو 100 ألف فقط لازم تزيد من 100 ألف أكتر من 100
+
+48
+00:04:44,850 --> 00:04:44,910
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+49
+00:04:44,910 --> 00:04:49,450
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+50
+00:04:49,450 --> 00:04:50,830
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+51
+00:04:50,830 --> 00:04:50,850
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+52
+00:04:50,850 --> 00:04:50,850
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+53
+00:04:50,850 --> 00:04:50,850
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+54
+00:04:50,850 --> 00:04:50,850
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+55
+00:04:50,850 --> 00:04:53,290
+أكتر من 100 أكتر من 100 أكتر من 100 أكتر من 100
+
+56
+00:04:53,290 --> 00:04:59,780
+أكتر من 100 أكتمثلًا، في هذه الحالة، يتم تخلص
+
+57
+00:04:59,780 --> 00:05:03,980
+المال أو يتم تخلص المال أو يتم تخلص المال أو يتم
+
+58
+00:05:03,980 --> 00:05:07,280
+تخلص المال أو يتم تخلص المال أو يتم تخلص المال أو
+
+59
+00:05:07,280 --> 00:05:07,360
+يتم تخلص المال أو يتم تخلص المال أو يتم تخلص المال
+
+60
+00:05:07,360 --> 00:05:07,660
+أو يتم تخلص المال أو يتم تخلص المال أو يتم تخلص
+
+61
+00:05:07,660 --> 00:05:08,920
+المال أو يتم تخلص المال أو يتم تخلص المال أو يتم
+
+62
+00:05:08,920 --> 00:05:10,240
+تخلص المال أو يتم تخلص المال أو يتم تخلص المال أو
+
+63
+00:05:10,240 --> 00:05:12,780
+يتم تخلص المال أو يتم تخلص المال أو يتم تخلص المال
+
+64
+00:05:12,780 --> 00:05:15,540
+أو يتم تخلص المال أو يتم تخلص المال أو يتم تخلص
+
+65
+00:05:15,540 --> 00:05:21,370
+المال أو يتم تخلربما يكون مشابه لـ Investment
+
+66
+00:05:21,370 --> 00:05:23,770
+Multiplier وGovernment Spending Multiplier إذا
+
+67
+00:05:23,770 --> 00:05:26,650
+تذكر أن الـ Government Spending Multiplier إذا
+
+68
+00:05:26,650 --> 00:05:31,610
+أزداد الحكومة بقيمة 100 ألف دولار، فإن نتيجة
+
+69
+00:05:31,610 --> 00:05:33,830
+النتيجة الأخيرة أو الأزداد الأخيرة في الـ
+
+70
+00:05:33,830 --> 00:05:36,750
+Aggregate Output أو الـ Aggregate Income ستزداد
+
+71
+00:05:36,750 --> 00:05:41,470
+بقيمة أكتر من 100 ألف دولار، فهو يعتمد على قيمة
+
+72
+00:05:41,470 --> 00:05:44,550
+الـ Margin of Propensity لتخزينها أو لإنقاذها، صح؟
+
+73
+00:05:45,630 --> 00:05:53,250
+مع نفس الفكرة هنا في هذه الحالة لدينا شيء
+
+74
+00:05:53,250 --> 00:06:00,730
+يسمى المال مرتبط مال مرتبط
+
+75
+00:06:00,730 --> 00:06:04,710
+مال مرتبط مال مرتبط مال مرتبط مال مرتبط مال مرتبط
+
+76
+00:06:04,710 --> 00:06:08,190
+مال مرتبط مال مرتبط مال مرتبط مال مرتبط مال مرتبط
+
+77
+00:06:14,610 --> 00:06:22,790
+مع المستحيل المستحيل المستحيل المستحيل
+
+78
+00:06:22,790 --> 00:06:27,130
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+79
+00:06:27,130 --> 00:06:27,310
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+80
+00:06:27,310 --> 00:06:27,310
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+81
+00:06:27,310 --> 00:06:27,330
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+82
+00:06:27,330 --> 00:06:27,430
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+83
+00:06:27,430 --> 00:06:28,710
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+84
+00:06:28,710 --> 00:06:30,930
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+85
+00:06:30,930 --> 00:06:31,810
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+86
+00:06:31,810 --> 00:06:32,050
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+87
+00:06:32,050 --> 00:06:33,510
+المستحيل المستحيل المستحيل المستحيل المستحيل
+
+88
+00:06:33,510 --> 00:06:41,910
+المستحيل المست
+
+89
+00:06:43,410 --> 00:06:50,850
+إذا كانت المصادر الأولى أو المصادر الأولى أو
+
+90
+00:06:50,850 --> 00:06:57,290
+المصادر الأولى كانت أو كانت أكتر من 100 ألف دولار،
+
+91
+00:06:57,290 --> 00:07:03,550
+فإن مصادر المال كانت تتطور إلى 20 مرة من هذا
+
+92
+00:07:03,550 --> 00:07:07,670
+المقاليعني لو واحد حط ميت ألف دولار ك initial
+
+93
+00:07:07,670 --> 00:07:11,570
+deposit كوديعة أصلية ال money supply would expand
+
+94
+00:07:11,570 --> 00:07:16,910
+هيتوسع ال money supply بعشرين ضعف المبلغ هذا so
+
+95
+00:07:16,910 --> 00:07:27,650
+the money supply money supply would increase would
+
+96
+00:07:27,650 --> 00:07:37,820
+expand to how muchالوديعة الأصلية مرة المالي
+
+97
+00:07:37,820 --> 00:07:49,440
+ملتبلير الوديعة
+
+98
+00:07:49,440 --> 00:07:59,040
+الأصلية مرة المالي ملتبلير الوديعة
+
+99
+00:07:59,040 --> 00:08:03,360
+الأصلية مرة المالي ملتبلير في هذه الحالةالدفع
+
+100
+00:08:03,360 --> 00:08:09,920
+المالي ستتطلع إلى كم؟ الدفع الأول هو 100 ألف
+
+101
+00:08:09,920 --> 00:08:13,780
+دولار، صحيح؟
+
+102
+00:08:13,780 --> 00:08:23,220
+المرة المالية المتعددة، وهو 20 مليون دولار فالدفع
+
+103
+00:08:23,220 --> 00:08:27,000
+المالي ستتطلع إلى 2 مليون دولار
+
+104
+00:08:34,370 --> 00:08:42,470
+USD واضحة ولا مش واضحة مين قايده طيب شباب اه okay
+
+105
+00:08:42,470 --> 00:08:47,870
+as we mentioned that if someone deposit one
+
+106
+00:08:47,870 --> 00:08:50,910
+hundred thousand dollar the value of money supply
+
+107
+00:08:50,910 --> 00:08:53,930
+would expand to not only by one hundred thousand
+
+108
+00:08:53,930 --> 00:08:58,490
+dollar it would expand by more than amount by the
+
+109
+00:08:58,490 --> 00:09:01,370
+value of multiplier right the money multiplier
+
+110
+00:09:01,990 --> 00:09:07,250
+الفرمولة التي تستخدمها لتخطيط اتفاق المال هو
+
+111
+00:09:07,250 --> 00:09:12,210
+الوديعة
+
+112
+00:09:12,210 --> 00:09:16,450
+الأصلية الوديعة الأصلية هي 100000 درهم مرتبط المال
+
+113
+00:09:18,190 --> 00:09:21,330
+مضروبة في قيمة المضاعف المضاعف النقود which equals
+
+114
+00:09:21,330 --> 00:09:24,370
+how much is the initial deposit one hundred
+
+115
+00:09:24,370 --> 00:09:27,970
+thousand dollar and the money multiplier as you
+
+116
+00:09:27,970 --> 00:09:31,770
+see equals twenty so one hundred thousand times
+
+117
+00:09:31,770 --> 00:09:36,690
+twenty equals two million حصل
+
+118
+00:09:36,690 --> 00:09:44,330
+ضرب عادي تمام okay so let's go to the exercise and
+
+119
+00:09:44,330 --> 00:09:44,850
+complete
+
+120
+00:09:48,230 --> 00:09:54,370
+الفكرة لذلك دعونا
+
+121
+00:09:54,370 --> 00:10:04,070
+نعود او حسنا تكمل المسألة كما ترى لدينا المعلومات
+
+122
+00:10:04,070 --> 00:10:10,170
+التالية عن الاقتصاد والأسئلة هي ما هو مقاومة
+
+123
+00:10:10,170 --> 00:10:13,630
+المساعدة بالضبط مقاومة المساعدة
+
+124
+00:10:16,680 --> 00:10:19,360
+مقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+125
+00:10:19,360 --> 00:10:21,120
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+126
+00:10:21,120 --> 00:10:26,520
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+127
+00:10:26,520 --> 00:10:34,640
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+128
+00:10:34,640 --> 00:10:38,780
+بالمقارنة
+
+129
+00:10:38,780 --> 00:10:45,680
+بالمقارنة بالمقارنة بالمقارنة بالمقارنة
+
+130
+00:10:46,310 --> 00:10:55,350
+ماذا بعد ذلك؟ لذلك يقل إلى 5% تفرح للسيناريو ماذا
+
+131
+00:10:55,350 --> 00:11:00,190
+هو المعدل المالي في هذه الاقتصاد؟ المعدل المالي
+
+132
+00:11:00,190 --> 00:11:05,010
+يقل 1 عشان مقارنة المعدل المالي والذي يقل 20
+
+133
+00:11:05,010 --> 00:11:09,650
+مقارنة، صحيح؟ ماذا بعد ذلك؟ تفرح للسيناريو تبقى
+
+134
+00:11:09,650 --> 00:11:17,830
+على الأولى 100 ألف دولار كدفعالدولة المالية ستتطور
+
+135
+00:11:17,830 --> 00:11:22,790
+إلى كم؟ هذا هو السؤال، لذلك لدينا تطور في الدولة
+
+136
+00:11:22,790 --> 00:11:28,590
+المالية باستخدام الانتجارات الأولى المالية المزيد
+
+137
+00:11:28,590 --> 00:11:29,570
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+138
+00:11:29,570 --> 00:11:30,270
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+139
+00:11:30,270 --> 00:11:30,270
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+140
+00:11:30,270 --> 00:11:30,790
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+141
+00:11:30,790 --> 00:11:30,990
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+142
+00:11:30,990 --> 00:11:30,990
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+143
+00:11:30,990 --> 00:11:30,990
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+144
+00:11:30,990 --> 00:11:30,990
+من المزيد من المزيد من المزيد من المزيد من المزيد
+
+145
+00:11:30,990 --> 00:11:31,810
+من المزيد من
+
+146
+00:11:39,270 --> 00:11:42,750
+السيناريو إذا تغيّر مقاومة الحصول على مقاومة
+
+147
+00:11:42,750 --> 00:11:43,550
+الحصول على مقاومة الحصول على مقاومة الحصول على
+
+148
+00:11:43,550 --> 00:11:46,510
+مقاومة الحصول على مقاومة الحصول على مقاومة الحصول
+
+149
+00:11:46,510 --> 00:11:50,230
+على مقاومة الحصول على مقاومة الحصول على مقاومة
+
+150
+00:11:50,230 --> 00:11:50,250
+الحصول على مقاومة الحصول على مقاومة الحصول على
+
+151
+00:11:50,250 --> 00:11:53,970
+مقاومة الحصول على مقاومة الحصول على مقاومة الحصول
+
+152
+00:11:53,970 --> 00:11:56,390
+على مقاومة الحصول على مقاومة الحصول على مقاومة
+
+153
+00:11:56,390 --> 00:11:57,650
+الحصول على مقاومة الحصول على مقاومة الحصول على
+
+154
+00:11:57,650 --> 00:12:05,230
+مقاومة الحصول على مقاومة الحصول على مقاومة الحصول
+
+155
+00:12:05,230 --> 00:12:11,220
+على مقاومالرقم المطلوب يتغير من كم إلى 10% إذا
+
+156
+00:12:11,220 --> 00:12:16,360
+كداش في عندي أنا رقم المطلوب 10% يجب أن يتم تطبيقه
+
+157
+00:12:16,360 --> 00:12:20,360
+في كل البنوك، صح؟ هذا بتطبق على كل بنوك، ففي
+
+158
+00:12:20,360 --> 00:12:25,720
+الحالة الأولى، يجب أن يكون 10 ألف دولار في البنك
+
+159
+00:12:25,720 --> 00:12:30,180
+الأولى، صح؟ ففي هذه الحالة، يجب أن يكون العمول 90
+
+160
+00:12:30,180 --> 00:12:35,290
+ألف دولارلأ because the initial deposit كده؟ one
+
+161
+00:12:35,290 --> 00:12:38,970
+hundred thousand dollar أخدنا عشرة في المية as
+
+162
+00:12:38,970 --> 00:12:42,970
+required reserve عشرة تلاف كده؟ بيبقى تسعين ألف
+
+163
+00:12:42,970 --> 00:12:46,910
+تمام؟ تسعين ألف أجوا على البنك التاني so here we
+
+164
+00:12:46,910 --> 00:12:51,050
+have ninety thousand dollar right؟ كدهش منهم
+
+165
+00:12:51,050 --> 00:12:54,730
+required؟ عشرة في المية كدهش عشرة؟ تسعة تلاف
+
+166
+00:12:54,730 --> 00:12:58,210
+exactly nine thousand وبالتالي بيبقى عند ال loans
+
+167
+00:12:58,210 --> 00:13:03,890
+كده؟ واحد تمانين الف81000 درهم هذا اللي بيقدر
+
+168
+00:13:03,890 --> 00:13:08,750
+يعملهم lending البنك التاني صح حاضر شوف السؤال ايش
+
+169
+00:13:08,750 --> 00:13:12,390
+بيقول انه suppose ان ال required reserve ratio has
+
+170
+00:13:12,390 --> 00:13:16,470
+changed to 10% يعني بطل 5% ال required reserve
+
+171
+00:13:16,470 --> 00:13:21,910
+ratio تمام how much is the loan of the bank number
+
+172
+00:13:21,910 --> 00:13:26,970
+two اللي بيقدر يعملهم lendingوكما تعلمين، مقاومة
+
+173
+00:13:26,970 --> 00:13:30,210
+الـ required reserve ratio هي مقاومة على جميع
+
+174
+00:13:30,210 --> 00:13:35,930
+البنكين لأنها مقاومة على جميع البنكين لأنها مقاومة
+
+175
+00:13:35,930 --> 00:13:35,930
+على جميع البنكين لأنها مقاومة على جميع البنكين
+
+176
+00:13:35,930 --> 00:13:36,610
+لأنها مقاومة على جميع البنكين لأنها مقاومة على
+
+177
+00:13:36,610 --> 00:13:37,750
+جميع البنكين لأنها مقاومة على جميع البنكين لأنها
+
+178
+00:13:37,750 --> 00:13:40,010
+مقاومة على جميع البنكين لأنها مقاومة على جميع
+
+179
+00:13:40,010 --> 00:13:41,730
+البنكين لأنها مقاومة على جميع البنكين لأنها مقاومة
+
+180
+00:13:41,730 --> 00:13:43,110
+على جميع البنكين لأنها مقاومة على جميع البنكين
+
+181
+00:13:43,110 --> 00:13:45,890
+لأنها مقاومة على جميع البنكين ل
+
+182
+00:13:54,990 --> 00:13:57,330
+عشرة في المية عليهم break wild reserve كده، يش
+
+183
+00:13:57,330 --> 00:13:59,750
+بيصيروا عشر تلاف، وابتالي البنك الأول، the first
+
+184
+00:13:59,750 --> 00:14:02,650
+bank يداش بيعمل ال loans، تسعين ألف، تسعين ألف
+
+185
+00:14:02,650 --> 00:14:07,580
+أجوا as a deposit في البنك التانيعليهم 10% تسعة
+
+186
+00:14:07,580 --> 00:14:11,920
+تلاف تسعة تلاف كدهش تسعين ألف نقص تسعة تلاف واحد
+
+187
+00:14:11,920 --> 00:14:17,200
+تمانين ألف so we have loans by ninety thousand
+
+188
+00:14:17,200 --> 00:14:22,980
+dollars sorry eighty one thousand dollar right
+
+189
+00:14:22,980 --> 00:14:27,440
+واضحة الأمور ولا مش واضحة طيب so let's come back
+
+190
+00:14:27,440 --> 00:14:34,420
+to the idea and complete the exercises
+
+191
+00:14:47,150 --> 00:14:52,970
+بالتالي، كما ترى هنا في الوصفة، المرتبط المالي هو
+
+192
+00:14:52,970 --> 00:14:56,830
+المرتبط بمجموعة يمكن أن تزداد في كل دولار تزداد في
+
+193
+00:14:56,830 --> 00:14:57,530
+المحافظة
+
+194
+00:15:17,960 --> 00:15:22,320
+معظم المالي مالي مالي مالي مالي مالي مالي مالي
+
+195
+00:15:22,320 --> 00:15:23,120
+مالي مالي مالي مالي مالي مالي مالي مالي مالي مالي
+
+196
+00:15:23,120 --> 00:15:23,680
+مالي مالي مالي مالي مالي مالي مالي مالي مالي مالي
+
+197
+00:15:23,680 --> 00:15:24,360
+مالي مالي مالي مالي مالي مالي مالي مالي مالي مالي
+
+198
+00:15:24,360 --> 00:15:24,360
+مالي مالي مالي مالي مالي مالي مالي مالي مالي مالي
+
+199
+00:15:24,360 --> 00:15:24,360
+مالي مالي مالي مالي مالي مالي مالي مالي مالي مالي
+
+200
+00:15:24,360 --> 00:15:24,360
+مالي مالي مالي مالي مالي مالي مالي مالي مالي مالي
+
+201
+00:15:24,360 --> 00:15:26,270
+مالي مالي مالي مالي مالي مإنه الـ money supply
+
+202
+00:15:26,270 --> 00:15:30,390
+would expand .. it would expand by five times of
+
+203
+00:15:30,390 --> 00:15:35,150
+the initial deposits، صح؟ هيضعف خمس مرات بمقدار
+
+204
+00:15:35,150 --> 00:15:38,790
+الوديعة الأصلية، مظبوط ولا لأ؟ صح؟ هذا ال idea
+
+205
+00:15:38,790 --> 00:15:43,090
+طبعاً، so let's go to this example as you see or
+
+206
+00:15:43,090 --> 00:15:46,330
+an exercise the required reserve ratio is suppose
+
+207
+00:15:46,330 --> 00:15:48,690
+that the required reserve ratio equals five
+
+208
+00:15:48,690 --> 00:15:53,210
+percent the money multiplier is how much؟ money
+
+209
+00:15:53,210 --> 00:15:58,110
+multiplierequals one over five percent equals
+
+210
+00:15:58,110 --> 00:16:03,230
+twenty صح طب لو ميعطيني ال money multiplier قدش ال
+
+211
+00:16:03,230 --> 00:16:06,910
+required reserve ratio يعني هذا السؤال in this
+
+212
+00:16:06,910 --> 00:16:11,090
+case the money multiplier is eight or equals eight
+
+213
+00:16:11,090 --> 00:16:15,470
+how much is the required reserve ratio ارفي
+
+214
+00:16:15,470 --> 00:16:18,670
+القانون اللي هو money multiplier equals one over
+
+215
+00:16:18,670 --> 00:16:26,510
+RRRمعنى الـ Multiplier يعني 8 اكتر اكتر 8 اكتر 8
+
+216
+00:16:26,510 --> 00:16:42,030
+اكتر 8 اكتر 8 اكتر 8 اكتر
+
+217
+00:16:44,750 --> 00:16:51,110
+0.8 تمانية في المية خلاص that's it الإجابة eighty
+
+218
+00:16:51,110 --> 00:16:59,550
+percent تمام طيب ليش حسابات واحد تقسيم تمانية قداش
+
+219
+00:16:59,550 --> 00:17:03,770
+على القالع على طول بيطلع بجزء اتناش و نص يمكن في
+
+220
+00:17:03,770 --> 00:17:09,750
+المية twelve point five صح طيب
+
+221
+00:17:14,320 --> 00:17:22,080
+الان دعونا نتكلم عن المشروعات ومشروع مركزي البنك
+
+222
+00:17:22,080 --> 00:17:22,860
+او مجلس المحافظة الوطنية
+
+223
+00:17:29,640 --> 00:17:35,400
+الشركة الرئيسية تلقى رولة مهمة في الاقتصاد ونحن
+
+224
+00:17:35,400 --> 00:17:42,340
+لدينا الاختصارات التالية لهذه الانستجرامة رقم واحد
+
+225
+00:17:42,340 --> 00:17:47,160
+اختيار ادخل مقاسات البنك موضوع المقاصة التعالج من
+
+226
+00:17:47,160 --> 00:17:50,760
+وين؟ في الشركة الرئيسية ماذا اخر؟ تحكم نظام البنك
+
+227
+00:17:50,760 --> 00:17:57,090
+من ينظم نظام البنك؟ الشركة الرئيسيةمساعدة الشركات
+
+228
+00:17:57,090 --> 00:18:02,330
+في موقعات مالية صعبة، على سبيل المثال، إحدى
+
+229
+00:18:02,330 --> 00:18:05,510
+الشركات تتعامل مع مشكلة، تتعامل مع مقاومة، في هذه
+
+230
+00:18:05,510 --> 00:18:08,210
+الحالة، يمكن الشركة الأساسية أن تدفع هذه الشركة
+
+231
+00:18:08,210 --> 00:18:15,240
+لتحل المصادرة المالية أو لتخلص من المقاومةwhat
+
+232
+00:18:15,240 --> 00:18:19,720
+else managing exchange rates طبعا من اللي بتحكي
+
+233
+00:18:19,720 --> 00:18:22,760
+بال exchange rate أسعار الصرف العملات وليه ال
+
+234
+00:18:22,760 --> 00:18:26,160
+central bank what is control the merges between
+
+235
+00:18:26,160 --> 00:18:29,660
+banks بنك بدي اندمج مع بنك تاني مين اللي بيعمل ال
+
+236
+00:18:29,660 --> 00:18:33,420
+organization لل organizing للعملية ال central bank
+
+237
+00:18:33,420 --> 00:18:39,380
+what else examination of the banks to ensure that
+
+238
+00:18:39,380 --> 00:18:43,840
+they are financially sound مش هيك على بنوك من شغله
+
+239
+00:18:43,840 --> 00:18:47,940
+صحأموره المالية سليمة عشان موضوع ال corruption و
+
+240
+00:18:47,940 --> 00:18:52,500
+اللي هي setting of reserves requirements for all
+
+241
+00:18:52,500 --> 00:18:54,540
+financial institutions الموضوع اللي required
+
+242
+00:18:54,540 --> 00:18:59,140
+reserve ratio اللي حكينا فيه مظبوط و the last
+
+243
+00:18:59,140 --> 00:19:03,400
+thing is lender of the last resort أخر ملاذ للبنو
+
+244
+00:19:03,400 --> 00:19:06,680
+كانت تقترض أو تحل مشاكلها المالية هو ال central
+
+245
+00:19:06,680 --> 00:19:08,580
+bank yes طبعا و ال money supply yes
+
+246
+00:19:12,180 --> 00:19:18,640
+هنا كما تشاهد انه يتكلم عن افعالية مقاومة المال
+
+247
+00:19:18,640 --> 00:19:26,160
+على مقاومة المال كمان كمان كمان كمان كمان كمان
+
+248
+00:19:26,160 --> 00:19:29,740
+كمان
+
+249
+00:19:29,740 --> 00:19:34,580
+كمان كمان كمان كمان كمان كمان كمان كمان كمان كمان
+
+250
+00:19:34,580 --> 00:19:34,800
+كمان كمان كمان كمان كمان كمان كمان كمان كمان كمان
+
+251
+00:19:34,800 --> 00:19:40,620
+كمان كمان كمان كمان كمان كمان كمان كمان كمانهناك
+
+252
+00:19:40,620 --> 00:19:42,900
+علاقة عكسية بين مقاومة المال والمقاومة المفترضة
+
+253
+00:19:42,900 --> 00:19:46,500
+والمقاومة
+
+254
+00:19:46,500 --> 00:19:48,160
+المفترضة والمقاومة المفترضة والمقاومة المفترضة
+
+255
+00:19:48,160 --> 00:19:52,600
+والمقاومة المفترضة والمقاومة المفترضة والمقاومة
+
+256
+00:19:52,600 --> 00:19:55,280
+المفترضة والمقاومة المفترضة والمقاومة المفترضة
+
+257
+00:19:55,280 --> 00:19:56,940
+والمقاومة المفترضة والمقاومة المفترضة والمقاومة
+
+258
+00:19:56,940 --> 00:19:56,960
+المفترضة والمقاومة المفترضة والمقاومة المفترضة
+
+259
+00:19:56,960 --> 00:19:59,280
+والمقاومة المفترضة والمقاومة المفترضة والمقاومة
+
+260
+00:19:59,280 --> 00:20:04,460
+المفترضة والمقاومة المفترضة والمقاومة
+
+261
+00:20:04,460 --> 00:20:04,580
+المف
+
+262
+00:20:10,560 --> 00:20:14,300
+وبالتالي ال capacity for the commercial banks to
+
+263
+00:20:14,300 --> 00:20:17,500
+lend أيش بتصير؟ تنزل يعني سببز أنه ال bank كان
+
+264
+00:20:17,500 --> 00:20:23,040
+بيطلب 20% على كل ودي ابتجيب صار يطلب 30% عامليا ال
+
+265
+00:20:23,040 --> 00:20:25,380
+money supply شو بيقل؟ ال reserves الاحتياط اللي
+
+266
+00:20:25,380 --> 00:20:28,840
+موجود عند البنوكة أيش بتصير فيها؟ بيقل وبالتالي ال
+
+267
+00:20:28,840 --> 00:20:34,780
+money supply would what؟ decline here
+
+268
+00:20:34,780 --> 00:20:39,740
+is the idea كل هذاexactly كل احتياط بيصير required
+
+269
+00:20:39,740 --> 00:20:42,600
+أو ال required reserve اللي بيروح على ال central
+
+270
+00:20:42,600 --> 00:20:46,060
+bank بده يزيد وبتالي ال excess excess reserves
+
+271
+00:20:46,060 --> 00:20:49,200
+اللي موجودة عند البنوك اشمالها بدها تقل وبتالي
+
+272
+00:20:49,200 --> 00:20:52,760
+their capacity to lend would decline and then the
+
+273
+00:20:52,760 --> 00:20:56,940
+money supply would decline as well صح؟ اظبط ولا
+
+274
+00:20:56,940 --> 00:21:03,820
+لأ؟ طيب هذه ال idea تبعت ال page هذا كلهالقيم
+
+275
+00:21:03,820 --> 00:21:08,560
+التجارية كما ذكرت قبل أن القيم التجارية هي القيم
+
+276
+00:21:08,560 --> 00:21:15,600
+الدفع اللي يدفعه البنك للمجلد عندما يدفعه منها لما
+
+277
+00:21:15,600 --> 00:21:17,880
+بيجي البنك التجارة بديه يقترض من البنك المركزي
+
+278
+00:21:17,880 --> 00:21:21,120
+لازم يدفع دفع دفع هو ده القيم التجارية اللي أخدنا
+
+279
+00:21:21,120 --> 00:21:27,200
+المرة الماضية وهناك علاقة عكسية أيضا بين القيم
+
+280
+00:21:27,200 --> 00:21:31,340
+التجارية ومال المدفع تزيد القيم التجارية
+
+281
+00:21:35,530 --> 00:21:43,650
+leads to increasing of the cost of borrowing of
+
+282
+00:21:43,650 --> 00:21:51,650
+the commercial banks from the central bank صح
+
+283
+00:21:51,650 --> 00:21:56,090
+القدرة تبعت عمليا ال cost of borrowing بيزيد
+
+284
+00:21:56,090 --> 00:22:04,990
+فبالتالي the capacity or the value or amount of
+
+285
+00:22:07,070 --> 00:22:11,670
+Borrowing شو بيصير فيها ده؟ و decline exactly؟
+
+286
+00:22:11,670 --> 00:22:16,410
+بتبطل ابنه بتقترض من البنك المركزي؟ this leads to
+
+287
+00:22:16,410 --> 00:22:22,850
+what؟ انه ال money supply و ال decline كمان ال
+
+288
+00:22:22,850 --> 00:22:28,270
+reserves عندهم أشمالها بتقل صح؟ مظبوط ولا لأ؟ so
+
+289
+00:22:28,270 --> 00:22:31,430
+in general there is an inverse relationship
+
+290
+00:22:31,430 --> 00:22:33,730
+between the required reserve ratio and money
+
+291
+00:22:33,730 --> 00:22:38,730
+supplyAlso inverse relationship between the
+
+292
+00:22:38,730 --> 00:22:40,730
+discount rate and money supply
+
+293
+00:23:16,510 --> 00:23:18,990
+لنذهب الى عملية عملية عملية عملية عملية عملية
+
+294
+00:23:18,990 --> 00:23:18,990
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+295
+00:23:18,990 --> 00:23:22,170
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+296
+00:23:22,170 --> 00:23:22,210
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+297
+00:23:22,210 --> 00:23:24,090
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+298
+00:23:24,090 --> 00:23:24,090
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+299
+00:23:24,090 --> 00:23:24,170
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+300
+00:23:24,170 --> 00:23:26,610
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+301
+00:23:26,610 --> 00:23:29,450
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+302
+00:23:29,450 --> 00:23:34,810
+عملية عملية عملوالحماية الحكومية بشتري أو ببيع
+
+303
+00:23:34,810 --> 00:23:39,570
+حملة حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+304
+00:23:39,570 --> 00:23:43,090
+حملة حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+305
+00:23:43,090 --> 00:23:44,850
+حملة حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+306
+00:23:44,850 --> 00:23:45,270
+حملة حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+307
+00:23:45,270 --> 00:23:45,310
+حملة حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+308
+00:23:45,310 --> 00:23:45,310
+حملة حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+309
+00:23:45,310 --> 00:23:45,310
+حملة حملة حملة حملة حملة حملة حملة حملة حملة
+
+310
+00:23:59,660 --> 00:24:11,340
+إذا كنت أرغب في إضافة المال إذا كنت
+
+311
+00:24:11,340 --> 00:24:13,840
+أرغب في إضافة المال إذا كنت أرغب في إضافة المال
+
+312
+00:24:13,840 --> 00:24:20,000
+إذا كنت أرغب في إضافة المال إذا كنت أرغب في إضافة
+
+313
+00:24:20,000 --> 00:24:20,620
+المال إذا كنت أرغب في إضافة المال إذا كنت أرغب في
+
+314
+00:24:20,620 --> 00:24:25,200
+إضافة المال إذا كنت أرغب في إضافة المال إذا كنت
+
+315
+00:24:25,200 --> 00:24:26,260
+أرغب في إضافة المال
+
+316
+00:24:28,580 --> 00:24:31,360
+هذه هي .. في هذه الحالة، ستزال تزال تزال تزال تزال
+
+317
+00:24:31,360 --> 00:24:31,820
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+318
+00:24:31,820 --> 00:24:39,100
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+319
+00:24:39,100 --> 00:24:39,740
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+320
+00:24:39,740 --> 00:24:39,740
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+321
+00:24:39,740 --> 00:24:39,780
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+322
+00:24:39,780 --> 00:24:39,780
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+323
+00:24:39,780 --> 00:24:40,660
+تزال تزال تزال تزال تزال تزال
+
+324
+00:24:47,780 --> 00:24:50,560
+صح؟ So in this case what would happen؟ The money
+
+325
+00:24:50,560 --> 00:24:54,260
+supply would increase and vice versa for sure when
+
+326
+00:24:54,260 --> 00:24:58,280
+the government or the central bank wants to
+
+327
+00:24:58,280 --> 00:25:02,140
+decrease the money supply If the government or the
+
+328
+00:25:02,140 --> 00:25:05,920
+central bank wants to decrease the money supply it
+
+329
+00:25:05,920 --> 00:25:11,360
+can what? borrow money or take money and give the
+
+330
+00:25:11,360 --> 00:25:17,310
+people government securities صح؟بس هي الفكرة صعبة؟
+
+331
+00:25:17,310 --> 00:25:20,530
+طبعا هذه أكتر الأدوات بيستخدمها ال central bank
+
+332
+00:25:20,530 --> 00:25:26,310
+لأنه مالهاش side effects لأن ال discount rate has
+
+333
+00:25:26,310 --> 00:25:30,630
+negative effects or has some effects on the
+
+334
+00:25:30,630 --> 00:25:32,990
+investment and on the interest rate and then
+
+335
+00:25:32,990 --> 00:25:38,210
+investmentبس ال purchasing and selling of the
+
+336
+00:25:38,210 --> 00:25:41,970
+government securities has less effects on the
+
+337
+00:25:41,970 --> 00:25:44,950
+economy or less negative effects on the economy
+
+338
+00:25:44,950 --> 00:25:50,290
+وبالتالي أكتر أداء بيستخدمها ال central bank تمام؟
+
+339
+00:25:50,290 --> 00:25:56,970
+طيب So
+
+340
+00:25:56,970 --> 00:26:02,120
+as you see in this statementan open market
+
+341
+00:26:02,120 --> 00:26:05,260
+purchases of securities by the federal results in
+
+342
+00:26:05,260 --> 00:26:10,540
+an increase in reserves شو اللي بيصير؟ لما بيشتروا
+
+343
+00:26:10,540 --> 00:26:13,780
+government securities و بيعطوا الناس مصارى، شو
+
+344
+00:26:13,780 --> 00:26:16,680
+اللي بيصير في ال reserves؟ أو بيعطيه للبنوك، شو
+
+345
+00:26:16,680 --> 00:26:20,520
+اللي بيصير في ال reserves؟ with increase، هايو ال
+
+346
+00:26:20,520 --> 00:26:23,160
+pricing، نحلله هيك
+
+347
+00:26:30,690 --> 00:26:37,810
+the purchasing of of
+
+348
+00:26:37,810 --> 00:26:43,050
+government securities اشترينا من الناس ورق شو
+
+349
+00:26:43,050 --> 00:26:47,210
+اعطيناهم money money this leads to شو بيعمل في ال
+
+350
+00:26:47,210 --> 00:26:49,290
+reserves الاحتياط اللي موجود عند الناس و ليه عند
+
+351
+00:26:49,290 --> 00:26:52,810
+البنوك exactly so this leads to increasing the
+
+352
+00:26:52,810 --> 00:26:58,670
+reserves and then ال money supply would increase
+
+353
+00:27:00,500 --> 00:27:07,140
+صح؟ طب يزيد بقداش؟ بقيمة ال money multiplier صح؟
+
+354
+00:27:07,140 --> 00:27:14,900
+مظبوط ولا لا؟ وهي الجملة هيك تمام؟ and vice versa
+
+355
+00:27:14,900 --> 00:27:20,320
+if the bank or the central bank sell or selling
+
+356
+00:27:20,320 --> 00:27:25,560
+the government of government securities leads to a
+
+357
+00:27:25,560 --> 00:27:32,840
+decreasing in reservesعلى البنك والعاملين وهو ما
+
+358
+00:27:32,840 --> 00:27:41,280
+يسبب في اتقال في مصادر المال بقنا
+
+359
+00:27:41,280 --> 00:27:45,200
+ورق للناس وخدنا منهم الفلوس شو صار فى مصادر المال
+
+360
+00:27:45,200 --> 00:27:52,360
+نزلت وبتالي المصادر المال نزلت اتقال صح؟ طبعا
+
+361
+00:27:52,360 --> 00:27:55,060
+بقيمة اللى هو ال money multiplier
+
+362
+00:27:59,750 --> 00:28:05,610
+بالتالي كما تشاهد، هذه هي الفائعات،
+
+363
+00:28:05,610 --> 00:28:13,890
+كما تشاهد، شركة اوبين ماركتoperations are the
+
+364
+00:28:13,890 --> 00:28:16,590
+federal preferred means of controlling the money
+
+365
+00:28:16,590 --> 00:28:20,330
+supply because طبعا البنك المركزي بيفضل أنه يستخدم
+
+366
+00:28:20,330 --> 00:28:23,930
+.. يستخدم ال open market operations يعني أكتر من
+
+367
+00:28:23,930 --> 00:28:27,070
+ال discount rate و ال required reserve ratio ليش؟
+
+368
+00:28:27,070 --> 00:28:30,590
+لأنه they can .. they can be used with some
+
+369
+00:28:30,590 --> 00:28:36,330
+precisions طبعا بدقة أكتر و فيه flexibility أنه
+
+370
+00:28:36,330 --> 00:28:42,340
+بيع و اشتري و هيك and fairly predictableطبعا موضوع
+
+371
+00:28:42,340 --> 00:28:48,580
+التنبؤ و ال .. let's go to the money supply and
+
+372
+00:28:48,580 --> 00:28:52,700
+money demand before going to this diagram or
+
+373
+00:28:52,700 --> 00:28:56,180
+figure let's analyze the relationship between the
+
+374
+00:28:56,180 --> 00:28:59,480
+money demand and money supply sorry and interest
+
+375
+00:28:59,480 --> 00:28:59,780
+rate
+
+376
+00:29:18,950 --> 00:29:23,970
+قيمة الدفع والمال
+
+377
+00:29:23,970 --> 00:29:28,770
+بشكل
+
+378
+00:29:28,770 --> 00:29:28,850
+عام
+
+379
+00:29:33,000 --> 00:29:37,620
+العرض النقد او المال المستخدم يتحرر او يقوم بتحريك
+
+380
+00:29:37,620 --> 00:29:40,740
+المال من مجلس البنك الرئيسي يعني بيجي البنك ويقولك
+
+381
+00:29:40,740 --> 00:29:44,160
+انا بدي العرض النقد بدنا نخليه 200 ألف دولار 200
+
+382
+00:29:44,160 --> 00:29:48,160
+مليون دولار مثلا تمام وبالتالي there is no
+
+383
+00:29:48,160 --> 00:29:51,300
+relationship between ال interest rate و ال money
+
+384
+00:29:51,300 --> 00:29:54,360
+supply انه زاد ال interest rate مابأثرش على ال
+
+385
+00:29:54,360 --> 00:29:57,320
+money supply because انه ال bank ال central bank
+
+386
+00:29:57,320 --> 00:30:00,200
+هو بيحدد انه عرض النقد بيكون عندنا 200 مليون وخلاص
+
+387
+00:30:00,200 --> 00:30:05,100
+مالوش دعوةإنه the interest rate has no effects on
+
+388
+00:30:05,100 --> 00:30:08,340
+the money supply لأنه البنك هو اللي بيحدد it so we
+
+389
+00:30:08,340 --> 00:30:14,200
+will see that the money supply is a vertical line
+
+390
+00:30:14,200 --> 00:30:19,400
+هذا we are talking about the money market هدف ال
+
+391
+00:30:19,400 --> 00:30:23,010
+money marketفي عندى طلب على النقود money demand
+
+392
+00:30:23,010 --> 00:30:26,570
+وفي money supply زى ال goods and services market
+
+393
+00:30:26,570 --> 00:30:30,530
+في عندى طلب على السلع وفي عرض للسلع فى ال labor
+
+394
+00:30:30,530 --> 00:30:34,110
+market فى عندى labor demand و labor supply فى ال
+
+395
+00:30:34,110 --> 00:30:39,450
+money market عندى money demand و money supply طبعا
+
+396
+00:30:39,450 --> 00:30:44,340
+ال money supply in general is a vertical lineهي
+
+397
+00:30:44,340 --> 00:30:49,620
+تقرية تعني أنه لا يوجد علاقة ما بين قيمة الدولة
+
+398
+00:30:49,620 --> 00:30:55,540
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+399
+00:30:55,540 --> 00:30:55,620
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+400
+00:30:55,620 --> 00:30:58,380
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+401
+00:30:58,380 --> 00:31:00,640
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+402
+00:31:00,640 --> 00:31:00,640
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+403
+00:31:00,640 --> 00:31:00,640
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+404
+00:31:00,640 --> 00:31:00,640
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+405
+00:31:00,640 --> 00:31:05,640
+والدولة والدولة والدولة والدولة والدولة والدولة
+
+406
+00:31:05,640 --> 00:31:09,660
+والدولة
+
+407
+00:31:09,660 --> 00:31:18,230
+والدوصار 6% بماني سابلاي او a بي ال quant of money
+
+408
+00:31:18,230 --> 00:31:24,030
+supplied would not change كونستان طب شو هو ال
+
+409
+00:31:24,030 --> 00:31:29,650
+interest rate بالمناسبة يعني تكلفة الاقتراض لأنه
+
+410
+00:31:29,650 --> 00:31:32,810
+suppose الفاعدة suppose that I would like to
+
+411
+00:31:32,810 --> 00:31:37,360
+withdraw a loan from the bankبيقول في عليك
+
+412
+00:31:37,360 --> 00:31:41,300
+interest خمسة في المية، عبارة عن إيش هاي؟ cost of
+
+413
+00:31:41,300 --> 00:31:49,820
+borrowing، مظبوط؟ هي تكلفة اقتراض، تمام؟ طيب لأ،
+
+414
+00:31:49,820 --> 00:31:55,400
+in general كله، in general يعني نظره من الوراق
+
+415
+00:31:55,400 --> 00:32:00,940
+حالة ما هو عبارة عن تكلفة اقتراض بروالأ لأ لأ
+
+416
+00:32:00,940 --> 00:32:03,640
+النظام الإسلامي بيبقى مشترق I was working as a
+
+417
+00:32:03,640 --> 00:32:08,380
+manager of the مرابحة system of the Islamic relief
+
+418
+00:32:08,380 --> 00:32:14,360
+six years ago the مرابحة system is completely
+
+419
+00:32:14,360 --> 00:32:21,000
+different from the commercial banks under the
+
+420
+00:32:21,000 --> 00:32:21,800
+مرابحة system
+
+421
+00:32:25,010 --> 00:32:33,650
+أو الناس اللي يريدون الهجوم يقوم بشراء سيارة و
+
+422
+00:32:33,650 --> 00:32:41,490
+يقوم بزيارة المجتمع اللي اعطاه المرابحة
+
+423
+00:32:53,720 --> 00:32:58,600
+في هذه الحالة، يمكن الاسلاميين أن يشتري السيارة
+
+424
+00:32:58,600 --> 00:33:07,580
+ويشتريها ومن ثم يقومون بتسليعها للشركة أو الشخص
+
+425
+00:33:07,580 --> 00:33:18,070
+الذي يريد التسليع بمعنى 5600$نعم، لتدفع المال
+
+426
+00:33:18,070 --> 00:33:23,410
+كإدارة حسنا، كما ترى، لذلك كما ذكرنا أن الدولة هي
+
+427
+00:33:23,410 --> 00:33:28,010
+محطة التدفع، صحيح؟ ومعظم المال، المعظم المعظم
+
+428
+00:33:28,010 --> 00:33:28,510
+المعظم المعظم المعظم المعظم المعظم المعظم المعظم
+
+429
+00:33:28,510 --> 00:33:29,570
+المعظم المعظم المعظم المعظم المعظم المعظم المعظم
+
+430
+00:33:29,570 --> 00:33:31,910
+المعظم المعظم المعظم المعظم المعظم المعظم المعظم
+
+431
+00:33:31,910 --> 00:33:34,870
+المعظم المعظم المعظم المعظم المعظم المعظم المعظم
+
+432
+00:33:34,870 --> 00:33:36,170
+المعظم المعظم المعظم المعظم المعظم المعظم المعظم
+
+433
+00:33:36,170 --> 00:33:40,790
+المعظم المعظم
+
+434
+00:33:40,790 --> 00:33:46,390
+المعظم المعظم
+
+435
+00:33:46,410 --> 00:33:50,870
+in the economy خلاص هي هيك so there is no
+
+436
+00:33:50,870 --> 00:33:55,610
+relationship between the interest rate on or there
+
+437
+00:33:55,610 --> 00:34:00,110
+is no effect of the interest rate on the quantity
+
+438
+00:34:00,110 --> 00:34:05,270
+of money supplied تمام؟ طيب what about the
+
+439
+00:34:05,270 --> 00:34:08,430
+relationship between the interest rate and money
+
+440
+00:34:08,430 --> 00:34:16,960
+demand suppose thatالقيمة أزالت، هذا يعني أن قيمة
+
+441
+00:34:16,960 --> 00:34:21,420
+التخزين أزالت، صح؟ شو بيصير في ال quantum money
+
+442
+00:34:21,420 --> 00:34:26,160
+demand؟ بده ينزل، صح؟ بالضبط، لأن قيمة التخزين
+
+443
+00:34:26,160 --> 00:34:32,920
+ستزال، صح ولا لأ؟ لذا دعونا نشرح العلاقة بين ال
+
+444
+00:34:32,920 --> 00:34:36,520
+money demand أو ال quantum money demanded وقيمة
+
+445
+00:34:36,520 --> 00:34:36,520
+التخزين
+
+446
+00:34:42,910 --> 00:34:49,370
+I means interest rate or R sometimes R interest
+
+447
+00:34:49,370 --> 00:34:52,010
+rate and this is the quantity of money demand
+
+448
+00:34:52,010 --> 00:34:56,990
+there
+
+449
+00:34:56,990 --> 00:35:00,190
+is an inverse relationship between the interest
+
+450
+00:35:00,190 --> 00:35:03,030
+rate and the quantity of money demand this is the
+
+451
+00:35:03,030 --> 00:35:08,770
+money demand curve الناس
+
+452
+00:35:08,770 --> 00:35:09,990
+ليش بتطلب المساري؟
+
+453
+00:35:13,680 --> 00:35:18,400
+عشان يشتري او يعمل speculation مضاربة
+
+454
+00:35:26,570 --> 00:35:29,850
+شو بتساوي في الـ quantity demanded for money for
+
+455
+00:35:29,850 --> 00:35:34,250
+speculation or for transaction؟ و ال decline صح
+
+456
+00:35:34,250 --> 00:35:37,130
+لأن ال cost of borrowing بزيد so the increasing of
+
+457
+00:35:37,130 --> 00:35:40,930
+interest rate leads to increasing the cost of
+
+458
+00:35:40,930 --> 00:35:45,850
+borrowing then
+
+459
+00:35:45,850 --> 00:35:51,050
+the amount or the quantity demanded for money
+
+460
+00:35:54,660 --> 00:35:58,880
+تتخلص من السبب في التحديات والتعامل بالتعامل
+
+461
+00:35:58,880 --> 00:36:00,260
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+462
+00:36:00,260 --> 00:36:02,480
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+463
+00:36:02,480 --> 00:36:04,000
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+464
+00:36:04,000 --> 00:36:05,240
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+465
+00:36:05,240 --> 00:36:05,980
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+466
+00:36:05,980 --> 00:36:06,220
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+467
+00:36:06,220 --> 00:36:06,560
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+468
+00:36:06,560 --> 00:36:16,100
+بالتعامل بالتعامل بالتعامل بالتعامل بالتعامل
+
+469
+00:36:20,600 --> 00:36:28,660
+و Q Money Demand 1 وهذا هو نقطة A انزعاج انترنت من
+
+470
+00:36:28,660 --> 00:36:38,180
+R1 إلى R2 من 5% إلى 10% أو 7% هذا يعيد إلى اقل من
+
+471
+00:36:38,180 --> 00:36:39,340
+المال المطالب
+
+472
+00:36:43,150 --> 00:36:48,990
+هذا هو النقطة B لذلك حركة الأموال والدماء هي تنقل
+
+473
+00:36:48,990 --> 00:36:56,010
+من اليسار إلى اليسار بالنسبة للعاملين كما تعلمون
+
+474
+00:36:56,010 --> 00:37:03,630
+أن في كل السوق يوجد ايقاليبريام في السوق الخاص
+
+475
+00:37:03,630 --> 00:37:11,070
+بالأموال والدماء ايقاليبريام
+
+476
+00:37:11,070 --> 00:37:15,380
+يحدثبالضبط، كمية المال المطلوبة من الأشياء
+
+477
+00:37:15,380 --> 00:37:16,760
+المطلوبة من الأشياء المطلوبة من الأشياء المطلوبة
+
+478
+00:37:16,760 --> 00:37:18,000
+من الأشياء المطلوبة من الأشياء المطلوبة من الأشياء
+
+479
+00:37:18,000 --> 00:37:19,240
+المطلوبة من الأشياء المطلوبة من الأشياء المطلوبة
+
+480
+00:37:19,240 --> 00:37:20,200
+من الأشياء المطلوبة من الأشياء المطلوبة من الأشياء
+
+481
+00:37:20,200 --> 00:37:20,840
+المطلوبة من الأشياء المطلوبة من الأشياء المطلوبة
+
+482
+00:37:20,840 --> 00:37:23,020
+من الأشياء المطلوبة من الأشياء المطلوبة من الأشياء
+
+483
+00:37:23,020 --> 00:37:23,360
+المطلوبة من الأشياء المطلوبة من الأشياء المطلوبة
+
+484
+00:37:23,360 --> 00:37:27,920
+من الأشياء المطلوبة من الأشياء المطلوبة من الأشياء
+
+485
+00:37:27,920 --> 00:37:31,530
+المطلفي كل السوق في السوق الخدمات والسوق العملي
+
+486
+00:37:31,530 --> 00:37:36,910
+وفي السوق المالي ، لذلك الانتقال في السوق المالي
+
+487
+00:37:36,910 --> 00:37:42,130
+يحدث عندما التطبيق المالي يتجاوز مع المصادر
+
+488
+00:37:42,130 --> 00:37:44,570
+المالية ، لذلك اعتمدي أن هذا هو المصادر المالية ،
+
+489
+00:37:44,570 --> 00:37:50,560
+أين هو الانتقال في نقطة A؟The money demand
+
+490
+00:37:50,560 --> 00:37:55,380
+intersects the money supply، this is our .. here
+
+491
+00:37:55,380 --> 00:38:00,200
+we have an equilibrium in the money market تمام؟
+
+492
+00:38:00,200 --> 00:38:02,500
+لسه المرة اللي جايب نكمل يعطيكم الأعافية شوية
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/SXMaL2Op6N4_postprocess.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/SXMaL2Op6N4_postprocess.srt
new file mode 100644
index 0000000000000000000000000000000000000000..ddb95193ee5da427eb4d5b41d7bf1fee2f8c8b57
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/SXMaL2Op6N4_postprocess.srt
@@ -0,0 +1,2052 @@
+1
+00:00:20,810 --> 00:00:25,370
+بسم الله الرحمن الرحيم اليوم إن شاء الله سنكمل
+
+2
+00:00:25,370 --> 00:00:32,250
+حديثنا عن المصطلحات المرتبطة بالميكروفانية كما
+
+3
+00:00:32,250 --> 00:00:37,430
+تعلمين في السلاسة الأخيرة نحكي عن بعض المصطلحات
+
+4
+00:00:37,430 --> 00:00:47,190
+المرتبطة بالميكروفانية ونحكي عنكيزيان تهوير وقصة
+
+5
+00:00:47,190 --> 00:00:51,210
+الانتجار عن الانتجار وكيف يمكن ان تتخلص قيمة
+
+6
+00:00:51,210 --> 00:00:57,010
+الانتجار بدون أي انتجار من الحكومة باعتبار قصة
+
+7
+00:00:57,010 --> 00:01:03,710
+الانتجار اليوم نحن ونقدم معلومات تاريخية عن فترة
+
+8
+00:01:03,710 --> 00:01:04,770
+الانتجار الكبير
+
+9
+00:01:08,760 --> 00:01:14,100
+اليوم سنكمل حديثنا عن نظرية كينزيا أو نظرية
+
+10
+00:01:14,100 --> 00:01:20,680
+الانفجار الكينزيا بعد تحويل كورونا العظيم كما
+
+11
+00:01:20,680 --> 00:01:26,160
+ذكرنا أنه في تحويل كورونا العظيم كان هناك عدد عمل
+
+12
+00:01:26,160 --> 00:01:28,820
+غير مستعمر عالي عدد المواطنين العزيزي للمواطنين
+
+13
+00:01:28,820 --> 00:01:32,120
+العزيزي للمواطنين العزيزي للمواطنين العزيزي
+
+14
+00:01:32,120 --> 00:01:32,460
+للمواطنين العزيزي للمواطنين العزيزي للمواطنين
+
+15
+00:01:32,460 --> 00:01:33,420
+العزيزي للمواطنين العزيزي للمواطنين العزيزي
+
+16
+00:01:33,420 --> 00:01:36,960
+للمواطنين العزيزي للمواطنين العزيزي للمواطنين
+
+17
+00:01:36,960 --> 00:01:37,980
+العزيزي للمواطنين العز
+
+18
+00:01:41,580 --> 00:01:47,700
+والتقليل من السعر والعاملات لم يقلل عدد عملية
+
+19
+00:01:47,700 --> 00:01:49,460
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+20
+00:01:49,460 --> 00:01:50,440
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+21
+00:01:50,440 --> 00:01:55,660
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+22
+00:01:55,660 --> 00:01:55,880
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+23
+00:01:55,880 --> 00:01:56,520
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+24
+00:01:56,520 --> 00:01:57,160
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+25
+00:01:57,160 --> 00:01:57,180
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+26
+00:01:57,180 --> 00:01:57,700
+عملية عملية
+
+27
+00:02:09,470 --> 00:02:16,410
+وكانت تستمر لمدة أكتر من 6 عاماً فرق العمليات
+
+28
+00:02:16,410 --> 00:02:23,870
+استمرت في التزامن وعقلاتها تتخلصت ولكن مشكلة
+
+29
+00:02:23,870 --> 00:02:35,210
+العمليات لم تتحلط لذلك في هذا الوقت السيد
+
+30
+00:02:35,210 --> 00:02:41,710
+كينز سيد جون مينيرد كينزوحاول ان يجد حل للمشكلة
+
+31
+00:02:41,710 --> 00:02:47,630
+وقال ان لكي تحل او تخلص الاستعمار او لكي تحل
+
+32
+00:02:47,630 --> 00:02:52,070
+الاستعمار او لكي تخلص عدد استعمار الاستعمار، يجب
+
+33
+00:02:52,070 --> 00:02:57,170
+أن يتعامل الحكومة في الاقتصاد باستخدام حكومة
+
+34
+00:02:57,170 --> 00:03:03,210
+اتفاقية او حكومة اتفاقية اتفاقية باستخدام اتفاقية
+
+35
+00:03:03,210 --> 00:03:05,070
+اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية
+
+36
+00:03:05,070 --> 00:03:05,490
+اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية
+
+37
+00:03:05,490 --> 00:03:09,500
+اتفاقية اتفاقية اتفاقية اتفوهو يعتبر أن الحكومة
+
+38
+00:03:09,500 --> 00:03:16,380
+يجب أن تدفع الانتجار بدلا من الانتجار، أو الانتجار
+
+39
+00:03:16,380 --> 00:03:23,940
+الانتجار. فهو يعتبر أن إذا أزداد الحكومة مستقبلته،
+
+40
+00:03:23,940 --> 00:03:32,340
+ازداد مستقبل الحكومة أو
+
+41
+00:03:32,340 --> 00:03:39,640
+مستقبلهذا يعني ماذا؟ هذا سيجعل المستخدمين
+
+42
+00:03:39,640 --> 00:03:42,900
+يشتغلوا على البيع أو يجعل المستخدمين يشتغلوا على
+
+43
+00:03:42,900 --> 00:03:48,040
+اتفاق الأسعار لأجهزتهم ومساعدتهم فهذا يجعل اتفاق
+
+44
+00:03:48,040 --> 00:03:50,200
+الأسعار يزال يزال يزال يزال يزال يزال يزال يزال
+
+45
+00:03:50,200 --> 00:03:56,620
+يزال يزال يزال يزال يزل يزل
+
+46
+00:03:56,620 --> 00:04:01,120
+يزل يزل يزل
+
+47
+00:04:01,120 --> 00:04:02,360
+يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل
+
+48
+00:04:02,360 --> 00:04:02,520
+يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل يزل
+
+49
+00:04:02,520 --> 00:04:09,780
+يزل يزل يزل يزل يزل يزل يهذا يعيد إلى ماذا؟ إزالة
+
+50
+00:04:09,780 --> 00:04:15,160
+الاختصارات أو الاختصارات المجموعة لأنه إذا كان
+
+51
+00:04:15,160 --> 00:04:22,120
+لدينا طلب عالي للأشياءهذا سيجعل المصادر أو المصادر
+
+52
+00:04:22,120 --> 00:04:27,420
+أو الشركة تنتج أكتر و أكتر، صحيح؟ لذا فإن زيادة
+
+53
+00:04:27,420 --> 00:04:31,900
+مطالبة المطالبة يؤدي إلى ماذا؟ يؤدي إلى أنها لديها
+
+54
+00:04:31,900 --> 00:04:38,460
+اتفاقين أكتر او اتفاقين أكتر. الأول هو زيادة في
+
+55
+00:04:38,460 --> 00:04:43,960
+المصادر. في نفس الوقت، إذا زادت مطالبة المطالبة،
+
+56
+00:04:43,960 --> 00:04:47,520
+هذا يؤدي إلى زيادة السعر أو مستوى السعر العام.
+
+57
+00:04:50,720 --> 00:04:56,120
+بالتالي إذا في هذا البرنامج أو هذا الفيجور كما ترى
+
+58
+00:04:56,120 --> 00:05:00,360
+هذه هي المطاولة المجاورة وهذه هي المطاولة المجاورة
+
+59
+00:05:00,360 --> 00:05:05,420
+يحدث ايقاليبريام عندما يكون هناك مقاومة بين
+
+60
+00:05:05,420 --> 00:05:09,260
+المطاولة المجاورة والمطاولة المجاورة هذا هو نقطة
+
+61
+00:05:09,260 --> 00:05:15,600
+الوصولة E1في هذه اللحظة فإن أجهزتنا أو أجهزتنا
+
+62
+00:05:15,600 --> 00:05:21,620
+المجاورة هي Y1 ومقارنة الأسعار هي P1
+
+63
+00:05:24,610 --> 00:05:29,730
+إذا كانت الحكومة تستخدم تغيير مصطلح التحقيق، فهذا
+
+64
+00:05:29,730 --> 00:05:34,850
+يعني أنها أزالت تتوقف، وهذا يؤدي إلى أزالة مطالبة
+
+65
+00:05:34,850 --> 00:05:38,050
+المطالبة، فهناك تغيير مصطلح التحقيق من مطالبة
+
+66
+00:05:38,050 --> 00:05:43,030
+المطالبة، لذلك لدينا نقطة ايقاليبية جديدة، وهي A2،
+
+67
+00:05:43,030 --> 00:05:49,900
+وهذا يؤدي إلى ماذا؟ كما ترى، هناك أزالة في YY يعني
+
+68
+00:05:49,900 --> 00:05:56,120
+نتيجة الميزانية من Y1 إلى Y2 وفي نفس الوقت، ستزال
+
+69
+00:05:56,120 --> 00:05:58,360
+السعر يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+70
+00:05:58,360 --> 00:06:04,060
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+71
+00:06:04,060 --> 00:06:04,340
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+72
+00:06:04,340 --> 00:06:06,820
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+73
+00:06:06,820 --> 00:06:06,840
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+74
+00:06:06,840 --> 00:06:07,740
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+75
+00:06:07,740 --> 00:06:12,860
+يزال يزال يزال
+
+76
+00:06:12,860 --> 00:06:15,960
+يزال
+
+77
+00:06:15,960 --> 00:06:18,040
+يز
+
+78
+00:06:20,320 --> 00:06:26,880
+الشركات تحتاج المزيد من العميل لتصنيف أو لتقديم
+
+79
+00:06:26,880 --> 00:06:33,820
+الانتجار للأشياء، صحيح؟ ففي هذه الحالة، الشركات
+
+80
+00:06:33,820 --> 00:06:39,140
+تحتاج المزيد من العميل أو العميل لتصنيف الانتجار.
+
+81
+00:06:39,660 --> 00:06:43,780
+لذلك، نحتاج المزيد من العميل، لذلك إتجار المزيد من
+
+82
+00:06:43,780 --> 00:06:47,820
+العميل أو العميل بميزة كم؟ بمزيد.
+
+83
+00:06:51,840 --> 00:07:03,040
+وهذا يؤدي إلى تقليل الانتجار، وبالتالي،
+
+84
+00:07:03,040 --> 00:07:10,900
+باعتبار الكنزيون، الحكومة بحاجة لحل تقليل انتجار
+
+85
+00:07:10,900 --> 00:07:17,740
+عالي أو تقليل انتجارالحكومة يجب أن تدفع اتفاق
+
+86
+00:07:17,740 --> 00:07:21,700
+المجموعات لأن اتفاق المجموعات اتفاق المجموعات
+
+87
+00:07:21,700 --> 00:07:24,240
+اتفاق المجموعات اتفاق المجموعات اتفاق المجموعات
+
+88
+00:07:24,240 --> 00:07:26,100
+اتفاق المجموعات اتفاق المجموعات اتفاق المجموعات
+
+89
+00:07:26,100 --> 00:07:28,080
+اتفاق المجموعات اتفاق المجموعات اتفاق المجموعات
+
+90
+00:07:28,080 --> 00:07:31,220
+اتفاق المجموعات اتفاق المجموعات اتفاق المجموعات
+
+91
+00:07:31,220 --> 00:07:38,980
+اتفاق المجموعات اتفاق المجموعات
+
+92
+00:07:38,980 --> 00:07:44,370
+اتفاق المجموعماذا؟ المزيد من العمل يجب أن يتم
+
+93
+00:07:44,370 --> 00:07:48,610
+إنتاجه، لذلك سيزداد طلب العمل، ثم ستتخلص عدد
+
+94
+00:07:48,610 --> 00:07:56,790
+العمليات، صحيح؟ هل هذا صحيح؟ صحيح، حسنًا، باعتبار
+
+95
+00:07:56,790 --> 00:08:01,670
+كينسيكي، كما
+
+96
+00:08:01,670 --> 00:08:07,950
+ترى، عندما ندفع طلب العمليات، ستتخلص عدد العمليات
+
+97
+00:08:10,250 --> 00:08:19,010
+للأسف، سعرها أكتر، لذلك تقليل العملية باستخدام
+
+98
+00:08:19,010 --> 00:08:23,610
+اتفاق الأسعار يؤدي إلى ماذا؟ يؤكد عملية الانفلاك،
+
+99
+00:08:23,610 --> 00:08:30,870
+لذلك، لتحل عملية عملية العملية العالية، في نفس
+
+100
+00:08:30,870 --> 00:08:38,940
+الوقت، سعرها أكتر، وكان يعتمد على ذلكالحكومة لا
+
+101
+00:08:38,940 --> 00:08:43,400
+تستطيع ان تزال تزال تزال تزال تزال تزال تزال تزال
+
+102
+00:08:43,400 --> 00:08:43,880
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+103
+00:08:43,880 --> 00:08:45,620
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+104
+00:08:45,620 --> 00:08:46,780
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+105
+00:08:46,780 --> 00:08:47,480
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+106
+00:08:47,480 --> 00:08:47,500
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+107
+00:08:47,500 --> 00:08:48,840
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+108
+00:08:48,840 --> 00:08:54,300
+تزال تزال تزال
+
+109
+00:08:55,880 --> 00:09:01,420
+على مصادر ومصادر واستثناء أو شيء مثل هذا هذا يسبب
+
+110
+00:09:01,420 --> 00:09:06,200
+في زيادة استخدامها والتي يسبب في تغيير كلمة صحيحة
+
+111
+00:09:06,200 --> 00:09:08,920
+من اتجار المطالبة من اتجار المطالبة 1 إلى اتجار
+
+112
+00:09:08,920 --> 00:09:14,540
+المطالبة 2 هذا يسبب في زيادة اتجار المطالبة من Y1
+
+113
+00:09:14,540 --> 00:09:22,480
+إلى Y2 دعونا نعتقد أن الحكومة استخدمت اتجارات
+
+114
+00:09:22,480 --> 00:09:29,630
+اضافية فيزيائيةأو استمتعت أكتر و أكتر هذا يؤدي إلى
+
+115
+00:09:29,630 --> 00:09:35,870
+إدعاء أو إضافة إضافة أكتر في الانتجار التطبيقية من
+
+116
+00:09:35,870 --> 00:09:38,930
+نقطة التطبيق التطبيقية 1 إلى نقطة التطبيق
+
+117
+00:09:38,930 --> 00:09:46,510
+التطبيقية 2 لدينا نقطة ايقاليبرين جديدة E3 صحيح؟
+
+118
+00:09:46,510 --> 00:09:47,630
+نعم
+
+119
+00:09:53,610 --> 00:09:58,110
+الخطوة التجارية والتجارة التجارية يعني أن الحكومة
+
+120
+00:09:58,110 --> 00:10:03,050
+تستطيع شراء .. لا لا لا الوضع المالي هو مرتبط
+
+121
+00:10:03,050 --> 00:10:07,820
+بالنظام الخزاني أو الشركة الأساسيةولكن في هذه
+
+122
+00:10:07,820 --> 00:10:12,580
+الحالة، يمكن أن تعمل أكتر عملاء، يمكن أن تشتري
+
+123
+00:10:12,580 --> 00:10:19,640
+أكتر أسلوب ومساعدة، يمكن أن تبني مبنية جديدة أو
+
+124
+00:10:19,640 --> 00:10:26,080
+تستخدم مبنية جديدة أو تقوم بتقسيم المجالات أو تقوم
+
+125
+00:10:26,080 --> 00:10:31,300
+بتقسيم المجالات، أليس
+
+126
+00:10:31,300 --> 00:10:36,750
+كذلك؟وأنا أرى في المجتمع الواضح أنهم يستخدموا
+
+127
+00:10:36,750 --> 00:10:41,770
+الوظيفة للتخلص من العمليات لتقليل حاجة العمليات،
+
+128
+00:10:41,770 --> 00:10:47,050
+هل هذه حلوة أو مشكلة؟ نعم، نعم، إنها حلوة، لأنه
+
+129
+00:10:47,050 --> 00:10:52,330
+لكي تحل أو تخلص من العمليات، يجب أن يستخدم الحكومة
+
+130
+00:10:52,330 --> 00:10:57,880
+تخلص من العمليات او تخلص من الحكومةلذلك، إنها
+
+131
+00:10:57,880 --> 00:11:02,520
+أفضل، إنها أفضل قرارية، ولكنها لديها إفاق نقلي أو
+
+132
+00:11:02,520 --> 00:11:06,740
+إفاق خاطئ لأن كما ترى، عندما قمنا بتحلل عدسة
+
+133
+00:11:06,740 --> 00:11:13,720
+العمليات العالية، عدسة الانفلاك أزداد وإذا
+
+134
+00:11:13,720 --> 00:11:20,950
+قررنا أن نخلص عدسة الانفلاك بإخلاص مصادر المالنحن
+
+135
+00:11:20,950 --> 00:11:25,010
+نصل إلى هذه القصص في القصص القادمة إن شاء الله،
+
+136
+00:11:25,010 --> 00:11:31,690
+وهذا يعيد إلى زيادة الانتجار، فما هي الحلول؟
+
+137
+00:11:31,690 --> 00:11:39,930
+الحلول هي أننا ندرس الحكومة لتحرير أهمية المجتمع
+
+138
+00:11:41,710 --> 00:11:44,270
+هل يمكننا أن نقبل قيمة عملية عملية عملية عملية
+
+139
+00:11:44,270 --> 00:11:45,210
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+140
+00:11:45,210 --> 00:11:49,010
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+141
+00:11:49,010 --> 00:11:51,750
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+142
+00:11:51,750 --> 00:11:52,470
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+143
+00:11:52,470 --> 00:11:53,430
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+144
+00:11:53,430 --> 00:11:54,810
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+145
+00:11:54,810 --> 00:11:58,030
+عملية عملية عملية عملية عملية
+
+146
+00:11:58,030 --> 00:11:59,250
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+147
+00:11:59,250 --> 00:12:09,330
+عملية عملية عملية عملية عملية عمل
+
+148
+00:12:09,840 --> 00:12:13,340
+في المستقبل الطويل، باعتبار النظر الكينيسياني أو
+
+149
+00:12:13,340 --> 00:12:17,400
+المدرسة الكينيسية ، فإن زيادة مستقبل الحكومة يؤدي
+
+150
+00:12:17,400 --> 00:12:20,720
+إلى زيادة المطالب المتعامل مع بعضهم البعض لكي
+
+151
+00:12:20,720 --> 00:12:26,640
+يصلوا إلى موظفة كامة هنا، وهذا يؤدي إلى زيادة Y من
+
+152
+00:12:26,640 --> 00:12:31,640
+Y1 إلى Y2 إلى Y3 ومعالجة
+
+153
+00:12:32,930 --> 00:12:40,970
+سيذهب الى P3 بعد هذا النقطة هذا النقطة يسمى توظيف
+
+154
+00:12:40,970 --> 00:12:46,770
+كامل يعني توظيف كامل بعد هذا النقطة إذا كان جميع
+
+155
+00:12:46,770 --> 00:12:54,310
+مصادر المجتمع في توظيف كامل إذا كان الحكومة بعد
+
+156
+00:12:54,310 --> 00:12:59,840
+هذا النقطةأي زيادة في مستقبل الحكومة تؤدي إلى
+
+157
+00:12:59,840 --> 00:13:05,580
+ماذا؟ تؤدي إلى زيادة دماغ المجتمع بدون زيادة في
+
+158
+00:13:05,580 --> 00:13:11,640
+الـY لذا لدينا ماذا؟ بعد الانتجار الواقعي فهناك
+
+159
+00:13:11,640 --> 00:13:17,080
+زيادة فقط في مستوى السعر العام أو انفلاش فقط لدينا
+
+160
+00:13:17,080 --> 00:13:20,660
+وليس هناك زيادة بعد هذا النقطة
+
+161
+00:13:23,450 --> 00:13:29,510
+لأن مطارد المساعدة العامة ستكون خطوة رقمية لذلك
+
+162
+00:13:29,510 --> 00:13:33,290
+باعتبار كنزين في المستقبل في المستقبل أو بعد
+
+163
+00:13:33,290 --> 00:13:36,030
+مجموعة التطبيقات العامة مطارد المساعدة العامة
+
+164
+00:13:36,030 --> 00:13:41,150
+ستكون خطوة رقمية لذا فإن أزمة الحكومة تدفع إلى
+
+165
+00:13:41,150 --> 00:13:45,690
+ماذا؟ إلى أزمة المطاردات العامة وإزامة الأسعار
+
+166
+00:13:45,690 --> 00:13:52,230
+بدون أزمة المطاردات العامة فهو مشكلة كبيرةالنتيجة
+
+167
+00:13:52,230 --> 00:13:58,450
+ستكون أننا لسنا .. أو لدينا موظفة مليئة ونسبة
+
+168
+00:13:58,450 --> 00:14:04,690
+عالية للإنفلاش ففي هذه الحالة اقترح للحكومة ان
+
+169
+00:14:04,690 --> 00:14:10,790
+تنفذ مالها او ان تستخدم قياسة
+
+170
+00:14:10,790 --> 00:14:13,950
+مالية
+
+171
+00:14:13,950 --> 00:14:24,290
+انكماشية لتنفذ أموال المجتمعلأن في هذه الحالة،
+
+172
+00:14:24,290 --> 00:14:31,130
+الحكومة ليست مفيدة أو غير مفيدة، صحيح؟ عندما تكون
+
+173
+00:14:31,130 --> 00:14:35,310
+المصادر عبارة عن رحلة عضوية، فحكومة الحكومة غير
+
+174
+00:14:35,310 --> 00:14:41,190
+مفيدة، صحيح؟ هل هذا صحيح؟ حسنًا، دعنا نذهب إلى شيء
+
+175
+00:14:41,190 --> 00:14:47,810
+آخر أو إلى أشياء أخرى أو أشياء مرتبطة بالمعروف
+
+176
+00:15:02,660 --> 00:15:09,240
+So as you see in 1936 the John Maynard Keynes
+
+177
+00:15:09,240 --> 00:15:12,940
+published the general theory of employment,
+
+178
+00:15:13,380 --> 00:15:18,000
+interest and moneyOkay
+
+179
+00:15:18,000 --> 00:15:23,100
+let's go to the fine tuning .. fine tuning
+
+180
+00:15:23,100 --> 00:15:30,890
+termFine tuning term .. term means اللي هو الدبطده
+
+181
+00:15:30,890 --> 00:15:35,250
+نعمل ضبط between the unemployment and inflation so
+
+182
+00:15:35,250 --> 00:15:41,330
+the fine tuning term is a phrase or in 1960 was a
+
+183
+00:15:41,330 --> 00:15:44,370
+phrase used by Walter Heller to refer to the
+
+184
+00:15:44,370 --> 00:15:49,970
+government roles in regulating inflation and
+
+185
+00:15:49,970 --> 00:15:54,050
+unemployment ننوعي
+
+186
+00:15:54,050 --> 00:15:58,190
+ما بين الinflation و ال unemployment yes
+
+187
+00:16:00,290 --> 00:16:08,910
+لنذهب إلى مصطلح آخر وهو Stag Inflation Stag
+
+188
+00:16:08,910 --> 00:16:14,090
+Inflation في العربية يعني الركود التضخمي Stag
+
+189
+00:16:14,090 --> 00:16:18,630
+Inflation .. في مدينة ال Stag Inflation لدينا عدد
+
+190
+00:16:18,630 --> 00:16:29,820
+عمليات عالي و عدد عمليات عالي باعتبار الكنزيينإذا
+
+191
+00:16:29,820 --> 00:16:32,960
+كان الحكومة ترغب في تقلي الانتجار، فالانتجار
+
+192
+00:16:32,960 --> 00:16:39,260
+سيزداد، صح؟ أو إذا كان الحكومة ترغب في تقلي
+
+193
+00:16:39,260 --> 00:16:47,480
+الانتجار، فالانتجار سيزداد، وفي السنة السادسة، في
+
+194
+00:16:47,480 --> 00:16:52,640
+السنة السادسة، الانتجار
+
+195
+00:16:52,640 --> 00:17:03,510
+يحدث أو يحدث، وفي هذه السنة، لديناوالسعر يزال يزال
+
+196
+00:17:03,510 --> 00:17:05,710
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+197
+00:17:05,710 --> 00:17:07,150
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+198
+00:17:07,150 --> 00:17:08,770
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+199
+00:17:08,770 --> 00:17:10,410
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+200
+00:17:10,410 --> 00:17:11,330
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+201
+00:17:11,330 --> 00:17:17,250
+يزال
+
+202
+00:17:21,490 --> 00:17:26,210
+هو أنه يتفاق مع نظرة كينسيا لأنه باعتبار نظرة
+
+203
+00:17:26,210 --> 00:17:29,990
+كينسيا إذا كان لدينا عدد عملاق عالي فلدينا عدد
+
+204
+00:17:29,990 --> 00:17:39,510
+عملاق عالي وكذلك وكذلك وكذلك وكذلك
+
+205
+00:17:39,510 --> 00:17:43,450
+وكذا
+
+206
+00:17:43,450 --> 00:17:44,290
+وكذا وكذا وكذا وكذا وكذا وكذا وكذا وكذا وكذا وكذا
+
+207
+00:17:44,290 --> 00:17:44,370
+وكذا وكذا وكذا وكذا وكذا وكذا وكذا وكذا وكذا وكذا
+
+208
+00:17:44,370 --> 00:17:51,030
+وكذا وكذا وكذا وكذا وكذا وكذا
+
+209
+00:17:51,030 --> 00:17:57,580
+وكذاstagnation has two parts or a word consists of
+
+210
+00:17:57,580 --> 00:18:08,120
+two parts stagnation and inflation stagnation it's
+
+211
+00:18:08,120 --> 00:18:15,800
+a word with two parts stagnation means
+
+212
+00:18:15,800 --> 00:18:20,080
+recession ركود
+
+213
+00:18:23,130 --> 00:18:31,350
+الثانية جزء منها هي الانفلاش ، لذلك انفلاش وانفلاش
+
+214
+00:18:31,350 --> 00:18:37,270
+وانفلاش وانفلاش ، لذلك انفلاش وانفلاش هو عندما
+
+215
+00:18:37,270 --> 00:18:42,590
+يرتفع سعر الأسعار بسرعة كما ترى انفلاش في مراتين
+
+216
+00:18:42,590 --> 00:18:50,510
+انفلاش أو مراتين عمليات عالية ، حسنًا ، لنذهب إلى
+
+217
+00:18:50,510 --> 00:19:01,190
+نفس المصطلحعن الاقتصاد الميكرويكوناميكي وهو اعتقد
+
+218
+00:19:01,190 --> 00:19:08,450
+انه انفلاش حسنًا، ثلاثة أشكال أو اعتبار من
+
+219
+00:19:08,450 --> 00:19:15,310
+الاقتصاد الميكرويكوناميكي ما الذي سنركز عليه عندما
+
+220
+00:19:15,310 --> 00:19:18,550
+ندرس الاقتصاد الميكرويكوناميكي، سنركز عليه
+
+221
+00:19:19,430 --> 00:19:25,170
+Inflation, Output Growth and Unemployment هؤلاء هم
+
+222
+00:19:25,170 --> 00:19:28,850
+المهمات المهمة لـ Macroeconomics شو الأشياء اللي
+
+223
+00:19:28,850 --> 00:19:33,090
+بركز عليها الـ Macroeconomics؟
+
+224
+00:19:33,090 --> 00:19:36,190
+لنعود إلى الاختصارات المرتبطة بالـ Macroeconomics
+
+225
+00:19:36,190 --> 00:19:42,410
+الأولة كما ترى هي Inflation Inflation هو ماذا؟ هو
+
+226
+00:19:42,410 --> 00:19:48,740
+مرتبط السعر العامأو زي زي زي زي زي زي زي زي زي زي
+
+227
+00:19:48,740 --> 00:19:49,860
+زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي
+
+228
+00:19:49,860 --> 00:19:52,720
+زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي
+
+229
+00:19:52,720 --> 00:19:53,060
+زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي
+
+230
+00:19:53,060 --> 00:19:56,600
+زي زي زي زي زي زي زي زي زي زي زي
+
+231
+00:19:56,600 --> 00:19:56,720
+زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي
+
+232
+00:19:56,720 --> 00:20:13,740
+زي زي زي زي
+
+233
+00:20:13,740 --> 00:20:23,500
+زيالعامة العامة اليوم هي عامة
+
+234
+00:20:23,500 --> 00:20:23,580
+عامة عامة عامة عامة عامة عامة عامة عامة عامة عامة
+
+235
+00:20:23,580 --> 00:20:26,940
+عامة عامة عامة عامة عامة عامة عامة عامة عامة عامة
+
+236
+00:20:26,940 --> 00:20:30,540
+عامة عامة عامة عامة عامة عامة عامة عامة عامة عامة
+
+237
+00:20:30,540 --> 00:20:31,300
+عامة عامة عامة عامة عامة عامة عامة عامة عامة عامة
+
+238
+00:20:31,300 --> 00:20:40,800
+عامة عامة عامة عامة عامة عامة عامة عامة عامة عامة
+
+239
+00:20:40,800 --> 00:20:46,750
+عهنا لدينا كلمة أخرى وهي Deflation Deflation هو
+
+240
+00:20:46,750 --> 00:20:58,270
+عكس انفلات انفلات انفلات انفلات انفلات انفلات
+
+241
+00:20:58,270 --> 00:21:01,930
+انفلات انفلات انفلات انفلات انفلات انفلات انفلات
+
+242
+00:21:01,930 --> 00:21:05,330
+انفلات
+
+243
+00:21:05,330 --> 00:21:05,870
+انفلات انفلات انفلات انفلات انفلات انفلات انفلات
+
+244
+00:21:05,870 --> 00:21:08,150
+انفلات انفلات انفلات انفلات انفلات انفلات انفلات
+
+245
+00:21:08,150 --> 00:21:08,170
+انفلات انفلات انفلات انفلات انفلات انفلات انفلات
+
+246
+00:21:08,170 --> 00:21:11,770
+انفلات ان
+
+247
+00:21:11,830 --> 00:21:16,490
+مثلًا، ما هي السبب الرئيسي للانفلاش؟ ما هي
+
+248
+00:21:16,490 --> 00:21:20,390
+الانتجارات الرئيسية للانفلاش؟ ما هي التأثيرات
+
+249
+00:21:20,390 --> 00:21:27,350
+للانفلاش؟ ومن يفيد من الانفلاش؟ومن الذين يحصلوا
+
+250
+00:21:27,350 --> 00:21:32,750
+ومن الذين يخسروا من الانفلاش هذه هي الأسئلة المهمة
+
+251
+00:21:32,750 --> 00:21:38,090
+وكيف يمكن الحكومة أن تتعامل مع الانفلاش لتنفعه؟ أو
+
+252
+00:21:38,090 --> 00:21:41,870
+كيف يمكن الحكومة أن تحل هذا المشكلة؟ هذه هي
+
+253
+00:21:41,870 --> 00:21:46,330
+الأسئلة المهمة التي يجب أن نسألها عندما ندرس
+
+254
+00:21:46,330 --> 00:21:53,110
+الانفلاش فنوما، صحيح؟ حسنا، دعنا نذهب إلى مجموعة
+
+255
+00:21:53,110 --> 00:21:58,670
+أخرىrelated to the macro economics which is the
+
+256
+00:21:58,670 --> 00:22:06,550
+business cycle دورة ال business the business cycle
+
+257
+00:22:06,550 --> 00:22:11,390
+is the cycle of short term ups and downs in the
+
+258
+00:22:11,390 --> 00:22:18,930
+economy it's the cycle of short ups and downs in
+
+259
+00:22:18,930 --> 00:22:24,670
+the economy so let's draw or i will go to the
+
+260
+00:22:25,900 --> 00:22:36,360
+الصورة ترسم فكرة عملية العمل كما ترى في هذه الصورة
+
+261
+00:22:36,360 --> 00:22:47,540
+هذه هي عملية العمل نحن لدينا خطوط عامة أو خطوط
+
+262
+00:22:47,540 --> 00:22:54,240
+الخروج الخروج وهذا
+
+263
+00:22:54,240 --> 00:22:54,740
+هو الوقت
+
+264
+00:22:58,080 --> 00:23:03,740
+السلسل العملية هي عملية عملية عملية عملية عملية
+
+265
+00:23:03,740 --> 00:23:04,620
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+266
+00:23:04,620 --> 00:23:04,680
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+267
+00:23:04,680 --> 00:23:09,820
+عملية عملية عملية عملية
+
+268
+00:23:09,820 --> 00:23:14,260
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+269
+00:23:14,260 --> 00:23:14,280
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+270
+00:23:14,280 --> 00:23:25,140
+عملية عملية عملية عملية عملية عملية عمل
+
+271
+00:23:25,330 --> 00:23:32,230
+أو توسيع في الاقتصاد من الـ Growth إلى الـ Peak
+
+272
+00:23:32,230 --> 00:23:40,430
+هناك توسيع في الاقتصاد وتوسع في الاقتصاد وهذه
+
+273
+00:23:40,430 --> 00:23:44,890
+الفترة مرتبطة
+
+274
+00:23:44,890 --> 00:23:49,930
+بـ Low Unemployment وإزالة الأسعار العامة
+
+275
+00:23:53,210 --> 00:24:00,890
+الوقت التنفيذي يعني أن هناك طلب عال للأشياء و
+
+276
+00:24:00,890 --> 00:24:07,810
+لدينا طلب عال للعملاء فالوظيفة
+
+277
+00:24:07,810 --> 00:24:15,090
+ستزاد و لا وظيفة ستتخلص، صحيح؟ من النقطة الى الـ
+
+278
+00:24:15,090 --> 00:24:23,330
+Troth ماذا ترى؟ إنها حالة عكسيةAt recession or
+
+279
+00:24:23,330 --> 00:24:27,790
+contraction, the same meaning contraction or
+
+280
+00:24:27,790 --> 00:24:32,550
+recession حالة ركود, in this during this period we
+
+281
+00:24:32,550 --> 00:24:40,040
+have high unemployment rateالسعر مبالغ ، نعم السعر
+
+282
+00:24:40,040 --> 00:24:44,120
+مبالغ خلال هذا الوقت ، لذلك ، و لذلك كما ترى ،
+
+283
+00:24:44,120 --> 00:24:49,800
+دعنا نعود إلى المفهوم أو الاسم من عملية العمل ،
+
+284
+00:24:49,800 --> 00:24:57,980
+والذي هو أقصر من هذا الوقت إلى وقت قصير أو وقت
+
+285
+00:24:57,980 --> 00:25:01,620
+قصير من هذا الوقت إلى وقت قصير ، هؤلاء هم أعوام
+
+286
+00:25:01,620 --> 00:25:02,200
+قصيرة
+
+287
+00:25:04,810 --> 00:25:11,410
+في الاقتصاد، صحيح؟ هل هذا صحيح؟ حسنًا، دعنا نعود
+
+288
+00:25:11,410 --> 00:25:24,350
+إلى المصطلح المصطلح
+
+289
+00:25:24,350 --> 00:25:29,030
+المصطلح المصطلح المصطلح يعني المصطلح المتوسط
+
+290
+00:25:29,030 --> 00:25:32,590
+المصطلح المصطلح المصطلح المصطلح المصطلح المصطلح
+
+291
+00:25:32,590 --> 00:25:32,750
+المصطلح المصطلح المصطلح المصطلح المصطلح المصطلح
+
+292
+00:25:32,750 --> 00:25:33,770
+المصطلح المصطلح المصطلح المصطلح المصطلح المصطلح
+
+293
+00:25:33,770 --> 00:25:33,790
+المصطلح المصطلح المصطلح المصطلح المصطلح المصطلح
+
+294
+00:25:33,790 --> 00:25:37,500
+المصطلح المa great output مجموعة كلية للإنتاج
+
+295
+00:25:37,500 --> 00:25:43,060
+تبعنا during a period of time recession
+
+296
+00:25:48,360 --> 00:25:52,880
+أعتقد أنك لديك فكرة عن الانتقال، لذلك دعنا نذهب
+
+297
+00:25:52,880 --> 00:25:57,860
+إلى مفهوم الانتقال كما ترى، الانتقال هو الوقت في
+
+298
+00:25:57,860 --> 00:25:59,560
+الوقت في الوقت في الوقت في الوقت في الوقت في الوقت
+
+299
+00:25:59,560 --> 00:26:01,640
+في الوقت في الوقت في الوقت في الوقت في الوقت في
+
+300
+00:26:01,640 --> 00:26:07,900
+الوقت في الوقت في الوقت
+
+301
+00:26:07,900 --> 00:26:12,260
+في الوقت
+
+302
+00:26:13,360 --> 00:26:18,000
+إذا الإنتاج تبعنا نزل في فصليين متتاليين أو في
+
+303
+00:26:18,000 --> 00:26:21,360
+ربعين متتاليين in this case it would become what?
+
+304
+00:26:21,540 --> 00:26:27,720
+a recession the deep recession would become what?
+
+305
+00:26:27,940 --> 00:26:32,600
+a depression so if the recession period sustained
+
+306
+00:26:32,600 --> 00:26:36,300
+for a long time it would become a depression
+
+307
+00:26:36,300 --> 00:26:42,400
+right? so deep recession would become a depression
+
+308
+00:26:44,350 --> 00:26:50,090
+حسنًا ، نعم ، لذلك الانتقال و الانتقال أساسي يصبح
+
+309
+00:26:50,090 --> 00:26:57,230
+انتقال ، حسنًا ، نعم ، تستمر أو تستمر لوقت طويل ،
+
+310
+00:26:57,230 --> 00:27:02,630
+حسنًا ، دعنا نذهب إلى رقم الانتقال ، أعتقد أن كل
+
+311
+00:27:02,630 --> 00:27:07,010
+واحد منكم لديه فكرة عن مصطلح رقم الانتقال ، رقم
+
+312
+00:27:07,010 --> 00:27:12,530
+الانتقال هو او يساوي رقم الانتقال
+
+313
+00:27:17,310 --> 00:27:24,970
+equals the number of unemployed over of
+
+314
+00:27:24,970 --> 00:27:35,710
+unemployed over the labor force the labor force
+
+315
+00:27:35,710 --> 00:27:41,330
+the labor force includes the people who are
+
+316
+00:27:41,330 --> 00:27:47,870
+unemployed plus employedمثلًا في هذه الحالة مرة
+
+317
+00:27:47,870 --> 00:27:50,610
+مائية مرة مائية مائية مائية مائية مائية مائية
+
+318
+00:27:50,610 --> 00:27:50,930
+مائية مائية مائية مائية مائية مائية مائية مائية
+
+319
+00:27:50,930 --> 00:27:54,330
+مائية مائية مائية مائية مائية مائية مائية مائية
+
+320
+00:27:54,330 --> 00:27:54,450
+مائية مائية مائية مائية مائية مائية مائية مائية
+
+321
+00:27:54,450 --> 00:27:58,570
+مائية مائية
+
+322
+00:27:58,570 --> 00:28:02,330
+مائية
+
+323
+00:28:07,650 --> 00:28:11,730
+القيمة الانتجارية تقريبا تقريبا تقريبا تقريبا
+
+324
+00:28:11,730 --> 00:28:15,710
+تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا
+
+325
+00:28:15,710 --> 00:28:18,170
+تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا
+
+326
+00:28:18,170 --> 00:28:18,890
+تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا
+
+327
+00:28:18,890 --> 00:28:19,070
+تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا تقريبا
+
+328
+00:28:19,070 --> 00:28:35,150
+تقريبا تقريبا تقريبا تقريب
+
+329
+00:28:38,620 --> 00:28:43,420
+لنذهب إلى القرارات الحكومية التي يستخدمها الحكومة
+
+330
+00:28:43,420 --> 00:28:49,420
+أو القرارات التي يستخدمها الحكومة لتشغيل الاقتصاد
+
+331
+00:28:49,420 --> 00:29:00,940
+لتحل المشاكل المختلفة والاقتصاد كما ذكرت ربما20
+
+332
+00:29:00,940 --> 00:29:08,080
+دقائق قبل ان يستخدم الحكومة اتفاقية اتفاقية
+
+333
+00:29:08,080 --> 00:29:11,280
+اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية
+
+334
+00:29:11,280 --> 00:29:11,620
+اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية
+
+335
+00:29:11,620 --> 00:29:13,400
+اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية
+
+336
+00:29:13,400 --> 00:29:14,160
+اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية
+
+337
+00:29:14,160 --> 00:29:16,340
+اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية اتفاقية
+
+338
+00:29:16,340 --> 00:29:22,920
+اتفاقية اتفاقية
+
+339
+00:29:22,920 --> 00:29:26,340
+اتفا
+
+340
+00:29:28,380 --> 00:29:33,200
+الحكومة تستطيع استخدام ثلاثة أسلحة أو أسلحة أساسية
+
+341
+00:29:33,200 --> 00:29:34,560
+أو أسلحة أساسية أو أسلحة أساسية أو أسلحة أساسية أو
+
+342
+00:29:34,560 --> 00:29:37,160
+أسلحة أساسية أو أسلحة أساسية أو أسلحة أساسية أو
+
+343
+00:29:37,160 --> 00:29:38,000
+أسلحة أساسية أو أسلحة أسلحة أساسية أو أسلحة أسلحة
+
+344
+00:29:38,000 --> 00:29:39,940
+أسلحة أسلحة أسلحة أسلحة أسلحة أسلحة أسلحة أسلحة
+
+345
+00:29:39,940 --> 00:29:46,020
+أسلحة أسلحة أسلحة أسلحة أسلحة أسلحة أسلحة أسلحة
+
+346
+00:29:46,020 --> 00:29:52,340
+أسلحة أسلحة أسلحة
+
+347
+00:29:57,020 --> 00:30:04,680
+نحن نتكلم عن اتصالين الرئيسية الواتس او
+
+348
+00:30:04,680 --> 00:30:10,680
+الانفاق
+
+349
+00:30:10,680 --> 00:30:16,300
+الحكومي الانفاق الحكومي او او او او او او او او او
+
+350
+00:30:16,300 --> 00:30:17,660
+او او او او او او او او او او او او او او او او او
+
+351
+00:30:17,660 --> 00:30:17,720
+او او او او او او او او او او او او او او او او او
+
+352
+00:30:17,720 --> 00:30:21,340
+او او او او او او او او او او او او او
+
+353
+00:30:21,340 --> 00:30:27,210
+اوصحيح؟ لذلك عندما نتكلم عن القيادة الفiscal نحن
+
+354
+00:30:27,210 --> 00:30:32,410
+نتكلم عن اتنين مواصفات الرئيسية الهجوم أو الهجوم
+
+355
+00:30:32,410 --> 00:30:35,650
+أو .. و .. و .. و .. و .. و .. و .. و .. و .. و ..
+
+356
+00:30:35,650 --> 00:30:36,150
+و .. و .. و .. و .. و .. و .. و .. و .. و .. و ..
+
+357
+00:30:36,150 --> 00:30:37,850
+و .. و .. و .. و .. و .. و .. و .. و .. و .. و ..
+
+358
+00:30:37,850 --> 00:30:38,110
+و .. و .. و .. و .. و .. و .. و .. و .. و .. و ..
+
+359
+00:30:38,110 --> 00:30:38,510
+و .. و .. و .. و .. و .. و .. و .. و .. و .. و ..
+
+360
+00:30:38,510 --> 00:30:38,570
+و .. و .. و .. و .. و .. و .. و .. و .. و .. و ..
+
+361
+00:30:38,570 --> 00:30:42,650
+و .. و .. و .. و .. و .. و ..
+
+362
+00:30:55,370 --> 00:30:58,830
+Expansion of fiscal policy يعني سياسة مالية توسعية
+
+363
+00:30:58,830 --> 00:31:07,730
+In this case, the government can use increase its
+
+364
+00:31:07,730 --> 00:31:12,330
+spending or
+
+365
+00:31:12,330 --> 00:31:18,070
+and decreasing
+
+366
+00:31:18,070 --> 00:31:19,090
+the taxes
+
+367
+00:31:29,690 --> 00:31:33,150
+إذا الحكومة زودت الانفاق للناس ماعناه الكلام
+
+368
+00:31:33,150 --> 00:31:41,790
+انتوسع او اذا اتفق او اتفق تجارب الناس بطل انه
+
+369
+00:31:41,790 --> 00:31:45,230
+ياخد تجارب من الناس انها جزء من تجارب التجارب
+
+370
+00:31:45,230 --> 00:31:55,720
+التجاربية نحن لدينا شيء آخر وهوهي تسمى كتركتشنية
+
+371
+00:31:55,720 --> 00:32:02,780
+فسيكال بلسية كتركشنية
+
+372
+00:32:02,780 --> 00:32:08,000
+فسيكال بلسية كتركشنية
+
+373
+00:32:08,000 --> 00:32:10,940
+فسيكال بلسية كتركشنية فسيكال بلسية كتركشنية فسيكال
+
+374
+00:32:10,940 --> 00:32:17,820
+بلسية كتركشنية فسيكال بلسية كتركشنية فسيكال بلسية
+
+375
+00:32:17,820 --> 00:32:18,120
+كتركشنية فسيكال بلسية كتركشنية فسيكال بلسية
+
+376
+00:32:18,120 --> 00:32:18,260
+كتركشنية فسيكال بلسية كتركشنية فسيكال بلسية
+
+377
+00:32:18,260 --> 00:32:18,300
+كتركشنية فسيكال بلسية كتركشنية فسيكال بلسية
+
+378
+00:32:18,300 --> 00:32:18,320
+كتركشنية فسي
+
+379
+00:32:21,450 --> 00:32:27,590
+أو إزالة المجالات إذا
+
+380
+00:32:27,590 --> 00:32:33,070
+قامت الحكومة بتخلص أو تخلص من المجالات فهي تخلص من
+
+381
+00:32:33,070 --> 00:32:36,730
+المجالات على المساعدة وعلى العمل وعلى ما يسمى
+
+382
+00:32:39,780 --> 00:32:46,980
+الخطوة التجارية التجارية إذا انتجت تجارة تجارة
+
+383
+00:32:46,980 --> 00:32:49,140
+تجارة تجارة تجارة تجارة تجارة تجارة تجارة تجارة
+
+384
+00:32:49,140 --> 00:32:52,440
+تجارة تجارة
+
+385
+00:32:52,440 --> 00:32:53,260
+تجارة تجارة تجارة تجارة تجارة تجارة تجارة تجارة
+
+386
+00:32:53,260 --> 00:32:53,300
+تجارة تجارة تجارة تجارة تجارة تجارة تجارة تجارة
+
+387
+00:32:53,300 --> 00:32:54,120
+تجارة تجارة تجارة تجارة تجارة تجارة تجارة تجارة
+
+388
+00:32:54,120 --> 00:32:54,740
+تجارة تجارة تجارة تجارة تجارة تجارة تجارة تجارة
+
+389
+00:32:54,740 --> 00:33:03,400
+تجارة تجارة تجارة تجارة تجارة تجارة
+
+390
+00:33:03,400 --> 00:33:07,460
+تجارة
+
+391
+00:33:07,460 --> 00:33:31,020
+تالحكومة تستخدم استخدام تجاربها
+
+392
+00:33:31,020 --> 00:33:39,670
+أو تجارب التجاربتقسيم المال او مجموعة المال يسمى
+
+393
+00:33:39,670 --> 00:33:42,170
+تقسيم المال او مجموعة المال تسمى تقسيم المال تسمى
+
+394
+00:33:42,170 --> 00:33:43,910
+تقسيم المال تسمى تقسيم المال تسمى تقسيم المال تسمى
+
+395
+00:33:43,910 --> 00:33:45,910
+تقسيم المال تسمى تقسيم المال تسمى تقسيم المال تسمى
+
+396
+00:33:45,910 --> 00:33:48,370
+تقسيم المال تسمى تقسيم المال تسمى تقسيم المال تسمى
+
+397
+00:33:48,370 --> 00:33:50,990
+تقسيم المال تسمى تقسيم المال تسمى تقسيم المال تسمى
+
+398
+00:33:50,990 --> 00:33:54,690
+تقسيم المال تسمى تقسيم المال تسمى تقسيم المال تسمى
+
+399
+00:33:54,690 --> 00:33:58,790
+تقسيم المال تسمى تقسيم المال تسمى تقسيم المال تسمى
+
+400
+00:33:58,790 --> 00:34:07,740
+تقسيم المال تسمى تقسيم المال تسمهنا نحن نتحدث عن
+
+401
+00:34:07,740 --> 00:34:11,060
+المصادر المالية، عندما نتحدث عن المصادر المالية،
+
+402
+00:34:11,060 --> 00:34:15,760
+كما ترى، السلسلة المالية أو السلسلة المالية هي
+
+403
+00:34:15,760 --> 00:34:20,040
+مصادر استخدام مصادر المصادر المالية، مصادر مصادر
+
+404
+00:34:20,040 --> 00:34:21,180
+مصادر مصادر مصادر مصادر مصادر مصادر مصادر مصادر
+
+405
+00:34:21,180 --> 00:34:21,500
+مصادر مصادر مصادر مصادر مصادر مصادر مصادر مصادر
+
+406
+00:34:21,500 --> 00:34:22,440
+مصادر مصادر مصادر مصادر مصادر مصادر مصادر مصادر
+
+407
+00:34:22,440 --> 00:34:22,460
+مصادر مصادر مصادر مصادر مصادر مصادر مصادر مصادر
+
+408
+00:34:22,460 --> 00:34:30,480
+مصادر مصادر مصادر ملذلك، من يتحكم بالمال في
+
+409
+00:34:30,480 --> 00:34:34,540
+الاقتصاد؟ الشركة الأساسية أو المحافظة الأمريكية؟
+
+410
+00:34:34,540 --> 00:34:40,960
+لذلك، عندما تحكم المحافظة الأمريكية المال في
+
+411
+00:34:40,960 --> 00:34:48,540
+الاقتصاد، إذا أزداد المحافظة الأمريكية المال، يسمى
+
+412
+00:34:48,540 --> 00:34:52,780
+ذلك تحقيق تحكم المال في الاقتصاد. لذلك، هنا نتحدث
+
+413
+00:34:52,780 --> 00:34:58,660
+عن المحافظة الماليةأو مصطلح المحافظة الأمريكية
+
+414
+00:34:58,660 --> 00:35:01,800
+للمال
+
+415
+00:35:01,800 --> 00:35:07,760
+أو المصادر المالية للمصادر
+
+416
+00:35:07,760 --> 00:35:17,580
+المالية للمصادر المالية للمصادر المالية للمصادر
+
+417
+00:35:17,580 --> 00:35:20,000
+المالية للمصادر المالية للمصادر المالية للمصادر
+
+418
+00:35:20,000 --> 00:35:20,900
+المالية للمصادر المالية للمصادر المالية للمصادر
+
+419
+00:35:20,900 --> 00:35:21,000
+المالية للمصادر المالية للمصادر المالية للمصادر
+
+420
+00:35:21,000 --> 00:35:22,280
+المالية للمصادر المالية للمصادر المالية للمصادوهي
+
+421
+00:35:22,280 --> 00:35:28,280
+مرتبطة بالأسلحة التي تستخدمها الشركة الأمريكية أو
+
+422
+00:35:28,280 --> 00:35:32,020
+الشركة الأساسية التي تستخدمها الشركة الأمريكية أو
+
+423
+00:35:32,020 --> 00:35:32,680
+الشركة الأساسية التي تستخدمها الشركة الأمريكية أو
+
+424
+00:35:32,680 --> 00:35:33,620
+الشركة الأساسية التي تستخدمها الشركة الأمريكية أو
+
+425
+00:35:33,620 --> 00:35:34,720
+الشركة الأساسية التي تستخدمها الشركة الأمريكية أو
+
+426
+00:35:34,720 --> 00:35:36,640
+الشركة الأساسية التي تستخدمها الشركة الأمريكية أو
+
+427
+00:35:36,640 --> 00:35:37,840
+الشركة الأساسية التي تستخدمها الشركة الأمريكية أو
+
+428
+00:35:37,840 --> 00:35:41,480
+الشركة الأمريكية أو الشركة الأمريكية أو الشركة
+
+429
+00:35:41,480 --> 00:35:42,380
+الأمريكية
+
+430
+00:35:47,160 --> 00:35:51,700
+باستخدام أسلحة مختلفة مثل الـ Discount Rate
+
+431
+00:35:51,700 --> 00:35:56,400
+وRequired Reserve Ratio و Open Market Operations
+
+432
+00:35:56,400 --> 00:36:00,060
+نحن سنكتشف كل هذه الأسلحة بشكل مستمر إن شاء الله
+
+433
+00:36:00,060 --> 00:36:05,780
+ولكن إذا كانت الحكومة أو الوظيفة الوطنية أزداد
+
+434
+00:36:05,780 --> 00:36:10,080
+مستخدماتها أو مستخدام المال يسمى بـ Expansion
+
+435
+00:36:10,080 --> 00:36:16,860
+Monetary Policy فإن أزداد مستخدم المال يعنيمقالة
+
+436
+00:36:16,860 --> 00:36:26,640
+تدفع المال تدفع المال تدفع المال تدفع المال تدفع
+
+437
+00:36:26,640 --> 00:36:31,640
+المال تدفع المال تدفع المال تدفع المال تدفع المال
+
+438
+00:36:31,640 --> 00:36:32,420
+تدفع المال تدفع المال تدفع المال تدفع المال تدفع
+
+439
+00:36:32,420 --> 00:36:32,460
+المال تدفع المال تدفع المال تدفع المال تدفع المال
+
+440
+00:36:32,460 --> 00:36:42,040
+تدفع المال تدفع المال تدفع المال تدفع
+
+441
+00:36:42,040 --> 00:36:44,220
+المال
+
+442
+00:36:46,250 --> 00:36:53,470
+هل لديك علاقات مع الـ Yes, yes, yes, بالتأكيد. إذا
+
+443
+00:36:53,470 --> 00:36:57,290
+كانت الحكومة .. إذا زمان المال أكتر في البلد، هذا
+
+444
+00:36:57,290 --> 00:37:04,150
+يؤدي إلى تقليل قوة الحصول على المال، صحيح؟ ولكنه
+
+445
+00:37:04,150 --> 00:37:10,970
+يمكن أن يدفع الاقتصادي بإقلاء عدد العمليات بإزالة
+
+446
+00:37:10,970 --> 00:37:16,070
+العمليات كما ترى، ولكنه يؤدي ..لإزالة عملية تغيير
+
+447
+00:37:16,070 --> 00:37:22,030
+عملية تغيير العمليات عندما
+
+448
+00:37:22,030 --> 00:37:29,350
+نتكلم عن مصادر المال أو مصادر المال المزيد كما
+
+449
+00:37:29,350 --> 00:37:36,310
+ذكرت يؤدي إلى ماذا؟ يؤدي إلى تغيير عمليات التغيير
+
+450
+00:37:39,120 --> 00:37:43,680
+و أقل قوة الحصول على المال ولكننا نصل إلى هذه
+
+451
+00:37:43,680 --> 00:37:51,390
+النقطة في تصريحة ان شاء الله في شهر 6just to
+
+452
+00:37:51,390 --> 00:37:53,970
+explain the relationship between spending and tax
+
+453
+00:37:53,970 --> 00:37:57,030
+yes you said that the government in expanding
+
+454
+00:37:57,030 --> 00:37:59,770
+physical policy increasing spending and decreasing
+
+455
+00:37:59,770 --> 00:38:03,530
+tax yes how the government can finance its
+
+456
+00:38:03,530 --> 00:38:07,810
+spending by decreasing the tax when spending the
+
+457
+00:38:07,810 --> 00:38:10,150
+relationship between spending and tax is positive
+
+458
+00:38:10,150 --> 00:38:12,530
+relationship and that's mean when they increase
+
+459
+00:38:12,530 --> 00:38:15,530
+spending they need to finance this spending by
+
+460
+00:38:15,530 --> 00:38:21,400
+increasing taxOkay بس يعني when we come back to
+
+461
+00:38:21,400 --> 00:38:25,080
+your point or your question you are talking about
+
+462
+00:38:25,080 --> 00:38:29,940
+or you're asking about two two main points the
+
+463
+00:38:29,940 --> 00:38:32,800
+government spending and the government taxes or
+
+464
+00:38:32,800 --> 00:38:38,600
+the tax collection right the problem is or the
+
+465
+00:38:38,600 --> 00:38:42,080
+government decision depends on what the economic
+
+466
+00:38:42,080 --> 00:38:46,920
+situation if we have high unemployment rateماذا
+
+467
+00:38:46,920 --> 00:38:51,720
+يجب أن يفعل الحكومة لإيقاف هذا المشكلة؟ يجب أن
+
+468
+00:38:51,720 --> 00:39:00,530
+تزيد مستقبلهاعلى مصادر مختلفة بشرح مصادر مختلفة
+
+469
+00:39:00,530 --> 00:39:02,030
+بشرح مصادر مختلفة بشرح مصادر مختلفة بشرح مصادر
+
+470
+00:39:02,030 --> 00:39:05,090
+مختلفة بشرح مصادر مختلفة بشرح مصادر مختلفة بشرح
+
+471
+00:39:05,090 --> 00:39:05,850
+مصادر مختلفة بشرح مصادر مختلفة بشرح مصادر مختلفة
+
+472
+00:39:05,850 --> 00:39:12,530
+بشرح مصادر مختلفة بشرح مصادر مختلفة بشرح مختلفة
+
+473
+00:39:12,530 --> 00:39:13,670
+بشرح مصادر مختلفة بشرح مختلفة بشرح مختلفة بشرح
+
+474
+00:39:13,670 --> 00:39:14,750
+مختلفة بشرح مختلفة بشرح مختلفة بشرح مختلفة بشرح
+
+475
+00:39:14,750 --> 00:39:14,810
+مختلفة بشرح مختلفة بشرح مختلفة بشرح مختلفة بشرح
+
+476
+00:39:14,810 --> 00:39:23,510
+مخت
+
+477
+00:39:23,540 --> 00:39:27,400
+كما ذكرنا أننا نتحدث عن أن لدينا عدد عمليات عالية
+
+478
+00:39:27,400 --> 00:39:32,200
+في نفس الوقت عندما يستخدم الحكومة او يزيد عمليات
+
+479
+00:39:32,200 --> 00:39:33,460
+عمليات عمليات عمليات عمليات عمليات عمليات عمليات
+
+480
+00:39:33,460 --> 00:39:33,520
+عمليات عمليات عمليات عمليات عمليات عمليات عمليات
+
+481
+00:39:33,520 --> 00:39:38,460
+عمليات عمليات عمليات عمليات عمليات عمليات عمليات
+
+482
+00:39:38,460 --> 00:39:38,960
+عمليات عمليات عمليات عمليات عمليات عمليات عمليات
+
+483
+00:39:38,960 --> 00:39:41,200
+عمليات عمليات عمليات عمليات عمليات عمليات عمليات
+
+484
+00:39:41,200 --> 00:39:46,200
+عمليات ع
+
+485
+00:39:48,250 --> 00:39:55,650
+هذا يعني أن الحكومة لديها مصادر مالية من المال
+
+486
+00:39:55,650 --> 00:40:02,110
+لديها مصادر
+
+487
+00:40:02,110 --> 00:40:04,570
+مالية من المال لديها مصادر مالية من المال لديها
+
+488
+00:40:04,570 --> 00:40:09,210
+مصادر مالية من المال لديها مصادر مالية من المال
+
+489
+00:40:09,210 --> 00:40:10,910
+لديها مصادر مالية من المال لديها مصادر مالية من
+
+490
+00:40:10,910 --> 00:40:11,050
+المال لديها مصادر مالية من المال لديها مصادر مالية
+
+491
+00:40:11,050 --> 00:40:11,250
+من المال لديها مصادر مالية من المال لديها مصادر
+
+492
+00:40:11,250 --> 00:40:11,710
+لديها مصادر مالية من المال لديها مصادر مالية من
+
+493
+00:40:11,710 --> 00:40:14,130
+المال لديها مصادر
+
+494
+00:40:20,960 --> 00:40:26,860
+أو تجارب تجارب تجارب تجارب
+
+495
+00:40:26,860 --> 00:40:27,580
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+496
+00:40:27,580 --> 00:40:28,720
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+497
+00:40:28,720 --> 00:40:31,800
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+498
+00:40:31,800 --> 00:40:32,220
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+499
+00:40:32,220 --> 00:40:32,260
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+500
+00:40:32,260 --> 00:40:33,820
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+501
+00:40:33,820 --> 00:40:45,540
+تجارب تجارب تجارب تج
+
+502
+00:40:48,730 --> 00:40:55,150
+لذلك هم مقارنة إزالة الإستخدام وإزالة التجارة من
+
+503
+00:40:55,150 --> 00:41:01,790
+المجالات إزالة الإستخدام وإزالة المجالات، صح؟ لذا
+
+504
+00:41:01,790 --> 00:41:10,250
+هناك علاقة خاطئة، صح؟ هل هذا واضح أو لا؟ حسنًا،
+
+505
+00:41:10,250 --> 00:41:19,770
+لذلك، وخطوة الأخيرة هي حركة الثقافةفي هذه الحالة،
+
+506
+00:41:19,770 --> 00:41:26,690
+يركز الحكومة على تشغيل المصادر المجاورة لطلب
+
+507
+00:41:26,690 --> 00:41:35,610
+المجاورة المجاورةالأسلحة هي الأسلحة التي تركز على
+
+508
+00:41:35,610 --> 00:41:39,550
+تشغيل المصادر المجاورة للطلب المجاور للطلب المجاور
+
+509
+00:41:39,550 --> 00:41:45,710
+للطلب المجاور للطلب المجاور للطلب المجاور للطلب
+
+510
+00:41:45,710 --> 00:41:56,270
+المجاور للطلب
+
+511
+00:41:56,450 --> 00:42:00,290
+بدلاً من يعني بدل ما تركز they focus on what
+
+512
+00:42:00,290 --> 00:42:05,910
+increasing supply or aggregate output instead of
+
+513
+00:42:05,910 --> 00:42:07,850
+the aggregate demand
+
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/TcVw3nzuTfg_raw.json b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/TcVw3nzuTfg_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..230f7b15436ab03faf84b47c129dd1dd7b0b3971
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/TcVw3nzuTfg_raw.json
@@ -0,0 +1 @@
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"text": "We have a term which is leakages out and injection Injection and leakages out Injection and leakages out", "tokens": [4360, 362, 257, 1433, 597, 307, 17143, 1660, 484, 293, 22873, 682, 1020, 313, 293, 17143, 1660, 484, 682, 1020, 313, 293, 17143, 1660, 484], "avg_logprob": -0.21980168441167244, "compression_ratio": 1.5294117647058822, "no_speech_prob": 0.0, "words": [{"start": 2149.05, "end": 2149.31, "word": "We", "probability": 0.11212158203125}, {"start": 2149.31, "end": 2149.75, "word": " have", "probability": 0.9677734375}, {"start": 2149.75, "end": 2150.39, "word": " a", "probability": 0.97314453125}, {"start": 2150.39, "end": 2150.65, "word": " term", "probability": 0.943359375}, {"start": 2150.65, "end": 2150.87, "word": " which", "probability": 0.9560546875}, {"start": 2150.87, "end": 2151.87, "word": " is", "probability": 0.97607421875}, {"start": 2151.87, "end": 2153.35, "word": " leakages", "probability": 0.800048828125}, {"start": 2153.35, "end": 2153.87, "word": 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leakages out means تسرب اه suppose that we work under the open economy and we have a government we have a government and we work under the open economy", "tokens": [259, 1020, 313, 1355, 11331, 4587, 1863, 17143, 1660, 484, 1355, 6055, 3794, 25513, 1975, 3224, 7297, 300, 321, 589, 833, 264, 1269, 5010, 293, 321, 362, 257, 2463, 321, 362, 257, 2463, 293, 321, 589, 833, 264, 1269, 5010], "avg_logprob": -0.15758383564832734, "compression_ratio": 1.5254237288135593, "no_speech_prob": 0.0, "words": [{"start": 2178.86, "end": 2179.48, "word": "injection", "probability": 0.8509114583333334}, {"start": 2179.48, "end": 2179.88, "word": " means", "probability": 0.84912109375}, {"start": 2179.88, "end": 2180.98, "word": " حقن", "probability": 0.9485677083333334}, {"start": 2180.98, "end": 2183.12, "word": " leakages", "probability": 0.650390625}, {"start": 2183.12, "end": 2183.54, "word": " out", "probability": 0.8701171875}, {"start": 2183.54, "end": 2184.0, "word": " means", "probability": 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you see this is a needle right and suppose that we would like to do an injection for the economy and I'm the government if I inject", "tokens": [6027, 39184, 2463, 6434, 13672, 1829, 31439, 2423, 39184, 460, 307, 20627, 382, 22873, 44945, 5016, 4587, 1863, 8978, 42963, 38149, 9381, 18513, 445, 257, 1623, 286, 576, 1565, 746, 382, 291, 536, 341, 307, 257, 11037, 558, 293, 7297, 300, 321, 576, 411, 281, 360, 364, 22873, 337, 264, 5010, 293, 286, 478, 264, 2463, 498, 286, 10711], "avg_logprob": -0.23151041815678278, "compression_ratio": 1.41, "no_speech_prob": 0.0, "words": [{"start": 2232.88, "end": 2233.6, "word": "الـ", "probability": 0.54205322265625}, {"start": 2233.6, "end": 2233.88, "word": " government", "probability": 0.271240234375}, {"start": 2233.88, "end": 2234.44, "word": " spending", "probability": 0.8623046875}, {"start": 2234.44, "end": 2234.64, "word": " اللي", "probability": 0.9404296875}, {"start": 2234.64, "end": 2234.74, "word": " هو", "probability": 0.97265625}, 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So it's called injection, injection in the economy, right? So as you see, the G is the government spending has a positive relationship with the aggregate output, right?", "tokens": [4575, 1020, 1355, 3496, 420, 3496, 1460, 294, 264, 5010, 11, 264, 26118, 5598, 576, 3488, 11, 558, 30, 407, 309, 311, 1219, 22873, 11, 22873, 294, 264, 5010, 11, 558, 30, 407, 382, 291, 536, 11, 264, 460, 307, 264, 2463, 6434, 575, 257, 3353, 2480, 365, 264, 26118, 5598, 11, 558, 30], "avg_logprob": -0.2407670487057079, "compression_ratio": 1.7124183006535947, "no_speech_prob": 4.172325134277344e-07, "words": [{"start": 2263.1, "end": 2263.76, "word": "Inject", "probability": 0.738037109375}, {"start": 2263.76, "end": 2264.2, "word": " means", "probability": 0.2071533203125}, {"start": 2264.2, "end": 2265.18, "word": " spend", "probability": 0.740234375}, {"start": 2265.18, "end": 2265.84, "word": " or", "probability": 0.62060546875}, {"start": 2265.84, "end": 2266.22, "word": " spend", "probability": 0.85546875}, {"start": 2266.22, "end": 2266.92, "word": " 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So in this case, the aggregate output would decline. So there is a negative relationship بين مين ومين بين ال taxes and the government output or the sorry the aggregate output وبالتالي it's classified as what? Leakage is out تمام طيب what about investment", "tokens": [3522, 311, 257, 47799, 307, 484, 570, 321, 15631, 420, 321, 1723, 10041, 11, 558, 30, 407, 294, 341, 1389, 11, 264, 26118, 5598, 576, 15635, 13, 407, 456, 307, 257, 3671, 2480, 49374, 3714, 9957, 4032, 2304, 9957, 49374, 2423, 10041, 293, 264, 2463, 5598, 420, 264, 2597, 264, 26118, 5598, 46599, 6027, 2655, 6027, 1829, 309, 311, 20627, 382, 437, 30, 1456, 514, 609, 307, 484, 46811, 10943, 23032, 1829, 3555, 437, 466, 6078], "avg_logprob": -0.34172076993174366, "compression_ratio": 1.5263157894736843, "no_speech_prob": 2.384185791015625e-07, "words": [{"start": 2299.71, "end": 2300.01, "word": "It's", "probability": 0.4466705322265625}, {"start": 2300.01, "end": 2300.11, "word": " a", "probability": 0.88916015625}, {"start": 2300.11, "end": 2300.31, "word": " leakage", "probability": 0.55078125}, {"start": 2300.31, "end": 2300.55, "word": " is", "probability": 0.33154296875}, {"start": 2300.55, "end": 2300.85, "word": " out", 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"end": 2374.61, "text": "export and import export and import export injection and imports is classified as leakages out", "tokens": [3121, 2707, 293, 974, 10725, 293, 974, 10725, 22873, 293, 41596, 307, 20627, 382, 17143, 1660, 484], "avg_logprob": -0.4548611227009032, "compression_ratio": 1.4242424242424243, "no_speech_prob": 0.0, "words": [{"start": 2359.11, "end": 2359.87, "word": "export", "probability": 0.55572509765625}, {"start": 2359.87, "end": 2360.09, "word": " and", "probability": 0.828125}, {"start": 2360.09, "end": 2360.49, "word": " import", "probability": 0.89697265625}, {"start": 2360.49, "end": 2361.09, "word": " export", "probability": 0.46337890625}, {"start": 2361.09, "end": 2361.63, "word": " and", "probability": 0.50830078125}, {"start": 2361.63, "end": 2362.13, "word": " import", "probability": 0.8369140625}, {"start": 2362.13, "end": 2364.15, "word": " export", "probability": 0.6953125}, {"start": 2364.15, "end": 2368.39, "word": " injection", "probability": 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ضمن", "probability": 0.968017578125}, {"start": 2388.51, "end": 2388.71, "word": " is", "probability": 0.1981201171875}, {"start": 2388.71, "end": 2389.31, "word": " classified", "probability": 0.75048828125}, {"start": 2389.31, "end": 2389.89, "word": " as", "probability": 0.9794921875}, {"start": 2389.89, "end": 2390.03, "word": " a", "probability": 0.916015625}, {"start": 2390.03, "end": 2390.29, "word": " leakage", "probability": 0.451171875}, {"start": 2390.29, "end": 2390.77, "word": " out", "probability": 0.5849609375}, {"start": 2390.77, "end": 2394.51, "word": " اه", "probability": 0.593505859375}, {"start": 2394.51, "end": 2395.47, "word": " yes", "probability": 0.900390625}, {"start": 2395.47, "end": 2396.21, "word": " yes", "probability": 0.8427734375}, {"start": 2396.21, "end": 2397.31, "word": " right", "probability": 0.908203125}, {"start": 2397.31, "end": 2397.99, "word": " طيب", "probability": 0.9638671875}, {"start": 2397.99, "end": 2398.57, "word": " so", 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C plus I When Y is larger than the aggregate expenditure, what do you see? C plus S is larger than C plus I Or S larger than I", "tokens": [3555, 6027, 39184, 26118, 40377, 6915, 437, 30, 383, 1804, 286, 1133, 398, 307, 4833, 813, 264, 26118, 40377, 11, 437, 360, 291, 536, 30, 383, 1804, 318, 307, 4833, 813, 383, 1804, 286, 1610, 318, 4833, 813, 286], "avg_logprob": -0.30839843228459357, "compression_ratio": 1.4782608695652173, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 2640.8599999999997, "end": 2641.66, "word": "بالـ", "probability": 0.4722391764322917}, {"start": 2641.66, "end": 2641.96, "word": " aggregate", "probability": 0.783203125}, {"start": 2641.96, "end": 2642.58, "word": " expenditure", "probability": 0.947265625}, {"start": 2642.58, "end": 2643.22, "word": " equals", "probability": 0.5478515625}, {"start": 2643.22, "end": 2643.54, "word": " what?", "probability": 0.7880859375}, {"start": 2643.76, "end": 2644.14, "word": " C", "probability": 0.5703125}, {"start": 2644.14, "end": 2644.76, "word": " plus", "probability": 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0.9908447265625}, {"start": 2670.66, "end": 2671.04, "word": " من", "probability": 0.98876953125}, {"start": 2671.04, "end": 2671.36, "word": " المستخدمات", "probability": 0.42589111328125}, {"start": 2671.36, "end": 2672.36, "word": " المخططة،", "probability": 0.5104573567708334}, {"start": 2672.36, "end": 2673.22, "word": " صحيح؟", "probability": 0.80537109375}, {"start": 2673.22, "end": 2673.7, "word": " وفي", "probability": 0.888916015625}, {"start": 2673.7, "end": 2673.98, "word": " هذه", "probability": 0.6357421875}, {"start": 2673.98, "end": 2675.28, "word": " الحالة،", "probability": 0.81298828125}, {"start": 2675.28, "end": 2675.7, "word": " أكتر", "probability": 0.4752349853515625}, {"start": 2675.7, "end": 2675.96, "word": " من", "probability": 0.94970703125}, {"start": 2675.96, "end": 2676.08, "word": " المستخدمات", "probability": 0.71572265625}, {"start": 2676.08, "end": 2676.08, "word": " المخططة", "probability": 0.847705078125}, {"start": 2676.08, "end": 2676.5, "word": " ترتفع", "probability": 0.53759765625}, {"start": 2676.5, "end": 2676.68, "word": " في", "probability": 0.8994140625}, {"start": 2676.68, "end": 2677.7, "word": " الانفجار،", "probability": 0.4480997721354167}, {"start": 2677.7, "end": 2678.1, "word": " ولماذا", "probability": 0.76483154296875}, {"start": 2678.1, "end": 2678.4, "word": " يجب", "probability": 0.8839518229166666}, {"start": 2678.4, "end": 2678.42, "word": " أن", "probability": 0.7451171875}, {"start": 2678.42, "end": 2679.28, "word": " يتخلص؟", "probability": 0.6208089192708334}, {"start": 2679.28, "end": 2679.94, "word": " من", "probability": 0.9521484375}, {"start": 2679.94, "end": 2680.6, "word": " 800", "probability": 0.4853515625}, {"start": 2680.6, "end": 2681.18, "word": " مليون", "probability": 0.80859375}, {"start": 2681.18, "end": 2681.52, "word": " دولار", "probability": 0.9261067708333334}, {"start": 2681.52, "end": 2681.76, "word": " إلى", "probability": 0.68896484375}, {"start": 2681.76, "end": 2682.38, "word": " 500", "probability": 0.9541015625}, {"start": 2682.38, "end": 2682.84, "word": " مليون", "probability": 0.9930013020833334}, {"start": 2682.84, "end": 2683.68, "word": " دولار،", "probability": 0.9637451171875}, {"start": 2683.68, "end": 2684.28, "word": " صحيح؟", "probability": 0.98759765625}, {"start": 2684.28, "end": 2684.9, "word": " ومع", "probability": 0.4967447916666667}, {"start": 2684.9, "end": 2684.9, "word": " ذلك", "probability": 0.6260986328125}, {"start": 2684.9, "end": 2685.82, "word": " بالتأكيد،", "probability": 0.7749430338541666}, {"start": 2685.82, "end": 2686.3, "word": " إذا", "probability": 0.7344970703125}, {"start": 2686.3, "end": 2687.86, "word": " كانت", "probability": 0.84619140625}, {"start": 2687.86, "end": 2688.48, "word": " أكتر،", "probability": 0.75283203125}], "temperature": 1.0}, {"id": 105, "seek": 270376, "start": 2693.08, "end": 2703.76, "text": "تمام؟ and why would increase in this case؟ تمام؟ صعب الأمور ولا ..؟ في شامبيجويس؟", "tokens": [39237, 10943, 22807, 293, 983, 576, 3488, 294, 341, 1389, 22807, 46811, 10943, 22807, 20328, 3615, 3555, 16247, 2304, 13063, 49429, 4386, 22807, 8978, 13412, 10943, 3555, 1829, 7435, 45865, 3794, 22807], "avg_logprob": -0.3468276515151515, "compression_ratio": 1.0934579439252337, "no_speech_prob": 1.7881393432617188e-07, "words": [{"start": 2693.08, "end": 2694.24, "word": "تمام؟", "probability": 0.6326497395833334}, {"start": 2694.24, "end": 2694.5, "word": " and", "probability": 0.5947265625}, {"start": 2694.5, "end": 2695.0, "word": " why", "probability": 0.64013671875}, {"start": 2695.0, "end": 2695.58, "word": " would", "probability": 0.912109375}, {"start": 2695.58, "end": 2696.22, "word": " increase", "probability": 0.91162109375}, {"start": 2696.22, "end": 2696.36, "word": " in", "probability": 0.8505859375}, {"start": 2696.36, "end": 2696.56, "word": " this", "probability": 0.96337890625}, {"start": 2696.56, "end": 2698.2, "word": " case؟", "probability": 0.769287109375}, {"start": 2698.2, "end": 2699.6, "word": " تمام؟", "probability": 0.6787109375}, {"start": 2699.6, "end": 2699.9, "word": " صعب", "probability": 0.9890950520833334}, {"start": 2699.9, "end": 2700.22, "word": " الأمور", "probability": 0.9814453125}, {"start": 2700.22, "end": 2700.38, "word": " ولا", "probability": 0.8212890625}, {"start": 2700.38, "end": 2701.66, "word": " ..؟", "probability": 0.610107421875}, {"start": 2701.66, "end": 2702.92, "word": " في", "probability": 0.47412109375}, {"start": 2702.92, "end": 2703.76, "word": " شامبيجويس؟", "probability": 0.66973876953125}], "temperature": 1.0}], "language": "ar", "language_probability": 1.0, "duration": 2705.96075, "duration_after_vad": 2526.8793749999863}
\ No newline at end of file
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/WzKjKjJst_k.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/WzKjKjJst_k.srt
new file mode 100644
index 0000000000000000000000000000000000000000..452c334fc8abf4c81724ba4ef41dfd849d674ebe
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/WzKjKjJst_k.srt
@@ -0,0 +1,1564 @@
+
+1
+00:00:20,990 --> 00:00:24,110
+بسم الله الرحمن الرحيم اليوم إن شاء الله سنكمل
+
+2
+00:00:24,110 --> 00:00:28,790
+القصة السادسة أو النقطة الأخيرة في القصة السادسة
+
+3
+00:00:28,790 --> 00:00:33,750
+ثم سنكمل القصة أو نبدأ في القصة الثامنة، صحيح؟
+
+4
+00:00:33,750 --> 00:00:36,630
+النقطة الأخيرة في القصة السادسة أو القصة السادسة
+
+5
+00:00:36,630 --> 00:00:43,950
+هي مواقع مالية مختلفة، كما تعلمون أن الشركة
+
+6
+00:00:43,950 --> 00:00:48,450
+المركزية ممكن تدفع أو تستخدم اقتصادات مختلفة لتدفع
+
+7
+00:00:48,450 --> 00:00:53,270
+أو تتعامل مع هذه الاقتصادات .. لدينا
+
+8
+00:00:53,270 --> 00:00:57,030
+اتصالات مالية من اتصالات الماليين أو اتصالات
+
+9
+00:00:57,030 --> 00:00:57,470
+الماليين أو اتصالات الماليين أو اتصالات الماليين
+
+10
+00:00:57,470 --> 00:00:57,950
+أو اتصالات الماليين أو اتصالات الماليين اتصالات
+
+11
+00:00:57,950 --> 00:01:01,370
+الماليين اتصالات الماليين اتصالات الماليين اتصالات
+
+12
+00:01:01,370 --> 00:01:05,350
+الماليين اتصالات الماليين اتصالات الماليين اتصالات
+
+13
+00:01:05,350 --> 00:01:09,670
+الماليين اتصالات الماليين اتصالات الماليين اتصالات
+
+14
+00:01:09,670 --> 00:01:14,440
+الماليين. في هذه الحالة، يمكن الشركة الأساسية أو
+
+15
+00:01:14,440 --> 00:01:19,180
+الوظيفة الأمريكية تقليل
+
+16
+00:01:19,180 --> 00:01:25,440
+مصادر المال أو تقليل مصادر المال أو تقليل
+
+17
+00:01:25,440 --> 00:01:26,300
+مصادر المال.
+
+18
+00:01:30,920 --> 00:01:33,900
+ماذا عن الطريقة الثانية للأسلحة؟ يسمى هذه الطريقة
+
+19
+00:01:33,900 --> 00:01:38,280
+الـ Easy Monetary Policy. ثم سنقوم بتحقيق أو تحقيق
+
+20
+00:01:38,280 --> 00:01:44,240
+تأثير الـ Tight و Easy Monetary Policy. الطريقة
+
+21
+00:01:44,240 --> 00:01:49,340
+الثانية للأسلحة هي Easy Monetary Policy أو
+
+22
+00:01:49,340 --> 00:01:54,160
+Expansionary، في هذه الحالة تسمى Contractionary.
+
+23
+00:01:57,140 --> 00:02:02,980
+مقالات المالية. هنا نحن نتكلم عن مقالات المالية
+
+24
+00:02:02,980 --> 00:02:12,280
+بسهولة. مقالات المالية أو اسمها مقالات 
+
+25
+00:02:12,280 --> 00:02:17,580
+المالية تتطور. في هذه الحالة الشركة الأساسية تتطور
+
+26
+00:02:17,580 --> 00:02:21,020
+مصادر المال أو تزيد مصادر المال.
+
+27
+00:02:23,860 --> 00:02:30,860
+دعونا نعود إلى دياغرام أو صورة تظهر تأثير مصادر
+
+28
+00:02:30,860 --> 00:02:36,580
+المال أو أسهل وأسهل منظمة المحافظة على الاقتصاد
+
+29
+00:02:36,580 --> 00:02:39,780
+كمجتمع كمجتمع كمجتمع كمجتمع كمجتمع كمجتمع كمجتمع
+
+30
+00:02:39,780 --> 00:02:40,020
+كمجتمع كمجتمع كمجتمع كمجتمع كمجتمع كمجتمع كمجتمع
+
+31
+00:02:40,020 --> 00:02:40,040
+كمجتمع كمجتمع كمجتمع كمجتمع كمجتمع كمجتمع كمجتمع
+
+32
+00:02:40,040 --> 00:02:47,120
+كمجتمع كمجتمع كمجتمع كمجتمع كمجتمع كمجتم
+
+33
+00:02:48,570 --> 00:02:56,210
+MD1. وهذا ما يسمى كتابة الإنترنت الإيكاليبية R1 QM1
+
+34
+00:02:56,210 --> 00:03:00,970
+كما ذكرنا قبل انتقال الاستخدام المحكمة المحكمة
+
+35
+00:03:00,970 --> 00:03:01,670
+المحكمة المحكمة المحكمة المحكمة المحكمة المحكمة
+
+36
+00:03:01,670 --> 00:03:03,650
+المحكمة المحكمة المحكمة المحكمة المحكمة المحكمة
+
+37
+00:03:03,650 --> 00:03:04,430
+المحكمة المحكمة المحكمة المحكمة المحكمة المحكمة
+
+38
+00:03:04,430 --> 00:03:04,950
+المحكمة المحكمة المحكمة المحكمة المحكمة المحكمة
+
+39
+00:03:04,950 --> 00:03:14,570
+المحكمة المحكمة المحكمة المحكمة المحكمة المحكمة
+
+40
+00:03:14,570 --> 00:03:18,520
+المهي التلات حاجات اللي ممكن أنها تعمل decreasing
+
+41
+00:03:18,520 --> 00:03:21,540
+لل money supply، صح؟ now suppose that the central
+
+42
+00:03:21,540 --> 00:03:24,300
+bank decided to decrease the money supply. شو اللي
+
+43
+00:03:24,300 --> 00:03:27,820
+بيصير؟ there is a leftward shifting في ال money
+
+44
+00:03:27,820 --> 00:03:35,180
+supply curve، صح؟ which leads to what؟ exactly so
+
+45
+00:03:35,180 --> 00:03:38,000
+we have an increasing in the interest rate and
+
+46
+00:03:38,000 --> 00:03:43,100
+decreasing the quantity of money في السوق المالي،
+
+47
+00:03:43,100 --> 00:03:48,300
+صح؟ إنه يسمى كما يسمى التعب أو التدخل من القيادة
+
+48
+00:03:48,300 --> 00:03:50,640
+المالية. التعب أو التدخل من القيادة المالية. التعب
+
+49
+00:03:50,640 --> 00:03:53,740
+أو التدخل من القيادة المالية. التعب أو التدخل من
+
+50
+00:03:53,740 --> 00:03:54,440
+القيادة المالية. التعب أو التدخل من القيادة المالية
+
+51
+00:03:54,440 --> 00:03:55,380
+التعب أو التدخل من القيادة المالية. التعب أو التدخل
+
+52
+00:03:55,380 --> 00:03:55,840
+من القيادة المالية. التعب أو التدخل من القيادة
+
+53
+00:03:55,840 --> 00:03:58,100
+المالية. التعب أو التدخل من القيادة المالية. التعب
+
+54
+00:03:58,100 --> 00:03:59,760
+أو التدخل من القيادة المالية. التعب أو التدخل من
+
+55
+00:03:59,760 --> 00:04:00,560
+القيادة المالية. التعب أو التدخل من القيادة المالية
+
+56
+00:04:00,560 --> 00:04:10,240
+التعب أو
+
+57
+00:04:10,240 --> 00:04:14,300
+التدخل من القيادة. في مشكلة؟ طيب إذا ال increasing في
+
+58
+00:04:14,300 --> 00:04:17,540
+ال money supply curve شو بيعمل؟ will decrease the
+
+59
+00:04:17,540 --> 00:04:25,280
+interest rate to R3. in
+
+60
+00:04:25,280 --> 00:04:29,320
+the next chapter we will analyze the effects of
+
+61
+00:04:30,200 --> 00:04:34,440
+أسهل وبسهولة تحقيق حكومة المال على السوق الخاص
+
+62
+00:04:34,440 --> 00:04:39,300
+بناءً على
+
+63
+00:04:39,300 --> 00:04:39,480
+الخاص. بناءً على السوق الخاص. بناءً على السوق الخاص. بنا
+
+64
+00:04:39,480 --> 00:04:40,180
+على السوق الخاص. بناءً على السوق الخاص. بناءً على السوق
+
+65
+00:04:40,180 --> 00:04:40,640
+الخاص. بناءً على السوق الخاص. بناءً على السوق الخاص. بنا
+
+66
+00:04:40,640 --> 00:04:41,540
+على السوق الخاص. بناءً على السوق الخاص. بناءً على السوق
+
+67
+00:04:41,540 --> 00:04:47,460
+الخاص. بناءً على السوق الخاص. بناءً على السوق الخاص. بنا
+
+68
+00:04:47,460 --> 00:04:52,720
+على السوق الخاص. بناءً على السوق الخاص. بناءً على السوق
+
+69
+00:04:52,720 --> 00:04:56,120
+الخاص. بناءً على
+
+70
+00:04:56,510 --> 00:05:00,730
+The interaction between the goods and services
+
+71
+00:05:00,730 --> 00:05:05,850
+market and the money market. In general, any
+
+72
+00:05:05,850 --> 00:05:09,630
+decision taken in the monetary market on the money
+
+73
+00:05:09,630 --> 00:05:13,270
+market has effects on the goods and services
+
+74
+00:05:13,270 --> 00:05:17,610
+market. أي قرار نأخذه في سوق النقد له تأثير على
+
+75
+00:05:17,610 --> 00:05:20,410
+indirect effects on the goods and services and
+
+76
+00:05:20,410 --> 00:05:26,010
+vice versa. نأخذ قرار في عالم الأسعار والمساعدات
+
+77
+00:05:26,010 --> 00:05:31,750
+بالتأكيد لديه تأثير أو تأثير على عالم المال لأن
+
+78
+00:05:31,750 --> 00:05:38,210
+هناك اتفاق بين هذين العالمين. في هذه القصة كما
+
+79
+00:05:38,210 --> 00:05:42,130
+ذكرنا، كل تركيزنا سيكون على هذه الجزئيات العلاقات
+
+80
+00:05:42,130 --> 00:05:49,870
+ما بين سوق النقد وسوق البضاعة والسلع والخدمات. طيب،
+
+81
+00:05:49,870 --> 00:05:54,810
+لنعود قريبًا إلى الاسم أو الفكرة أو الوضع أو الوضع
+
+82
+00:05:54,810 --> 00:05:55,570
+أو الوضع أو الوضع أو الوضع أو الوضع أو الوضع أو
+
+83
+00:05:55,570 --> 00:05:55,990
+الوضع أو الوضع أو الوضع أو الوضع أو الوضع أو الوضع
+
+84
+00:05:55,990 --> 00:05:56,550
+أو الوضع أو الوضع أو الوضع أو الوضع أو الوضع أو
+
+85
+00:05:56,550 --> 00:05:59,690
+الوضع أو الوضع أو الوضع أو الوضع أو الوضع أو الوضع
+
+86
+00:05:59,690 --> 00:05:59,830
+أو الوضع أو الوضع أو الوضع أو الوضع أو الوضع أو
+
+87
+00:05:59,830 --> 00:06:01,450
+الوضع أو الوضع أو الوضع أو الوضع أو الوضع أو الوضع
+
+88
+00:06:01,450 --> 00:06:07,610
+أو الوضع أو الوضع أو الوضع أو الوضع أو الوضع أو
+
+89
+00:06:07,610 --> 00:06:09,920
+الـ و وين بيصير فيه تبادل ما بين ال goods and
+
+90
+00:06:09,920 --> 00:06:13,820
+services. في هذا بيكون في end السوق وين بيكون ال
+
+91
+00:06:13,820 --> 00:06:17,080
+prices and aggregate output level. أشمله is
+
+92
+00:06:17,080 --> 00:06:21,720
+determined. يعني أين يتحدد أو يحد يتم تحديد ال
+
+93
+00:06:21,720 --> 00:06:25,880
+aggregate output التوازني في سوق البضاعة. طب in the
+
+94
+00:06:25,880 --> 00:06:30,380
+money market is or the money market is the market
+
+95
+00:06:30,380 --> 00:06:33,900
+in which the financial instruments are exchanged
+
+96
+00:06:33,900 --> 00:06:36,520
+مثلًا في الـ .. في الـ money التبادل ما بين الـ .. في
+
+97
+00:06:36,520 --> 00:06:39,820
+الأدوات المالية ما بين اللي هو الـ money demand و
+
+98
+00:06:39,820 --> 00:06:43,400
+الـ money supply، وإيه اللي بتحدد فيه؟ الـ Interest
+
+99
+00:06:43,400 --> 00:06:45,220
+Rate. الـ Interest Rate. الـ Equilibrium الـ
+
+100
+00:06:45,220 --> 00:06:53,700
+Interest Rate. الـ Interest
+
+101
+00:06:53,700 --> 00:06:57,500
+Rate. الـ Interest Rate. الـ Interest Rate. الـ
+
+102
+00:06:57,500 --> 00:06:57,800
+Interest Rate. الـ Interest Rate. الـ Interest Rate
+
+103
+00:06:57,800 --> 00:06:58,080
+الـ Interest Rate. الـ Interest Rate. الـ Interest
+
+104
+00:06:58,080 --> 00:06:58,200
+Rate. الـ Interest Rate. الـ Interest Rate. الـ
+
+105
+00:06:58,200 --> 00:06:59,860
+الـ Interest Rate. الـ Interest Rate. الـ Interest
+
+106
+00:06:59,860 --> 00:06:59,880
+Rate. الـ Interest Rate. الـ Interest Rate. الـ
+
+107
+00:06:59,880 --> 00:07:03,320
+الـ Interest Rate. الـ Interest
+
+108
+00:07:03,320 --> 00:07:07,400
+Rate. الـ
+
+109
+00:07:07,400 --> 00:07:19,080
+Interest هو الإيكاليبريام
+
+110
+00:07:19,080 --> 00:07:22,980
+دولة دولة دولة دولة دولة دولة دولة دولة دولة دولة
+
+111
+00:07:22,980 --> 00:07:25,700
+دولة دولة دولة دولة دولة دولة دولة دولة دولة دولة
+
+112
+00:07:25,700 --> 00:07:26,560
+دولة دولة دولة دولة دولة دولة دولة دولة دولة دولة
+
+113
+00:07:26,560 --> 00:07:37,520
+دولة دولة دولة دولة دولة دولة دولة
+
+114
+00:07:37,520 --> 00:07:37,960
+دولة دولة دولة دولة دولة دولة دولة دولة دولة دولة
+
+115
+00:07:37,960 --> 00:07:40,910
+دولة دولة دولة دولة declined as you know that
+
+116
+00:07:40,910 --> 00:07:44,190
+income is related to what to which to the goods
+
+117
+00:07:44,190 --> 00:07:53,770
+and services market، صح؟ يعني suppose exactly
+
+118
+00:07:55,370 --> 00:07:58,830
+يعني بدأ أبدأ أنا بلاش أبدأ في التحليل من عند ال
+
+119
+00:07:58,830 --> 00:08:03,010
+decreasing في ال income بس بدأ أشوف إنه suppose أن
+
+120
+00:08:03,010 --> 00:08:07,530
+ال government declined أو decided to decrease its
+
+121
+00:08:07,530 --> 00:08:10,070
+spending. يعني بدأ أبدأ من التحليل من السياسة
+
+122
+00:08:10,070 --> 00:08:13,110
+النقدية المالية وبعدين أو sorry من ال goods
+
+123
+00:08:13,110 --> 00:08:15,650
+السياسة the policy that related to the goods and
+
+124
+00:08:15,650 --> 00:08:18,490
+services market ونشوف ال effect تبعها على ال money
+
+125
+00:08:18,490 --> 00:08:24,980
+market. so suppose that الحكومة قررت تقليل تقليلاتها
+
+126
+00:08:24,980 --> 00:08:30,540
+أو تقليل تقليلات الحكومة. تقليلات الحكومة. تقليلات
+
+127
+00:08:30,540 --> 00:08:33,040
+الحكومة. تقليلات الحكومة. تقليلات الحكومة. تقليلات
+
+128
+00:08:33,040 --> 00:08:37,220
+الحكومة. تقليلات الحكومة. تقليلات الحكومة. تقليلات
+
+129
+00:08:37,220 --> 00:08:39,140
+الحكومة. تقليلات الحكومة. تقليلات الحكومة. تقليلات
+
+130
+00:08:39,140 --> 00:08:42,200
+الحكومة. تقليلات الحكومة. تقليلات الحكومة. تقليلات
+
+131
+00:08:42,200 --> 00:08:47,820
+الحكومة
+
+132
+00:08:47,820 --> 00:08:53,950
+تقليلات الحكومة. C plus I plus G plus X minus M
+
+133
+00:08:53,950 --> 00:08:58,750
+وبالتالي أي انخفاض في الـ C ولا في الـ I ولا في الـ
+
+134
+00:08:58,750 --> 00:09:02,410
+G ولا في الـ X or increasing في الـ M شو بيعمل؟
+
+135
+00:09:02,410 --> 00:09:05,710
+بيعمل decreasing لل aggregate expenditure، صح؟
+
+136
+00:09:05,710 --> 00:09:11,260
+مظبوط؟ إذا suppose إنه في عنده decreasing في ال
+
+137
+00:09:11,260 --> 00:09:13,000
+government spending، شو بيعمل في ال aggregate
+
+138
+00:09:13,000 --> 00:09:17,180
+expenditure؟ بينزلوا. طب this leads to increasing
+
+139
+00:09:17,180 --> 00:09:19,080
+aggregate demand، decreasing في ال aggregate
+
+140
+00:09:19,080 --> 00:09:22,140
+demand، شو بيعمل في ال aggregate output؟ ما فيش طلب
+
+141
+00:09:22,140 --> 00:09:25,320
+على البضاعة وبتاع الناس بتاعة تنزل النتج، صح؟
+
+142
+00:09:25,320 --> 00:09:28,440
+which leads to a decrease in the aggregate
+
+143
+00:09:28,440 --> 00:09:33,370
+output طب فش إنتاج معناه كلمة من ال income
+
+144
+00:09:33,370 --> 00:09:37,190
+aggregate income would decline صح؟ فش إنتاج فش حد
+
+145
+00:09:37,190 --> 00:09:40,310
+يبيعه بتالي the income the aggregate income would
+
+146
+00:09:40,310 --> 00:09:44,010
+decline so the decrease in aggregate output
+
+147
+00:09:44,010 --> 00:09:51,690
+leads to a decrease in aggregate income طيب ال
+
+148
+00:09:51,690 --> 00:09:53,590
+decrease في ال income شو بيعمل في ال money
+
+149
+00:09:53,590 --> 00:09:57,990
+demand exactly the decrease in income leads to a
+
+150
+00:09:57,990 --> 00:09:59,550
+decrease in money demand
+
+151
+00:10:04,570 --> 00:10:08,530
+So this leads to a right .. a leftward shift of
+
+152
+00:10:08,530 --> 00:10:11,170
+the money demand curve صح؟ يعني قبل ال interest rate
+
+153
+00:10:11,170 --> 00:10:15,470
+ماينزل there we have what؟ a leftward shift ..
+
+154
+00:10:15,470 --> 00:10:23,210
+leftward shift on the money demand curve طب
+
+155
+00:10:23,210 --> 00:10:26,830
+تعالوا على الرسم هنا ال leftward shift في ال
+
+156
+00:10:26,830 --> 00:10:30,310
+money demand curve شو بيعمل؟ بينزل ال interest
+
+157
+00:10:30,310 --> 00:10:34,630
+rate exactly لذلك نحن نحصل على موقع إيكويلبريوم جديد
+
+158
+00:10:34,630 --> 00:10:42,530
+حيث أن موقع إيكويلبريوم رقم رقم رقم رقم رقم رقم رقم
+
+159
+00:10:42,530 --> 00:10:47,830
+رقم رقم رقم رقم رقم رقم رقم رقم
+
+160
+00:10:47,830 --> 00:10:50,170
+رقم رقم رقم رقم رقم رقم رقم رقم رقم رقم رقم
+
+161
+00:10:50,170 --> 00:10:50,270
+رقم رقم رقم رقم رقم رقم رقم رقم رقم رقم رقم
+
+162
+00:10:50,270 --> 00:10:57,850
+رقم رقم رقم رقم رقم رقم رقم رقم رقم رق
+
+163
+00:11:02,490 --> 00:11:09,870
+exactly so this leads to a decrease and cost of
+
+164
+00:11:09,870 --> 00:11:18,350
+borrowing الاقتراض
+
+165
+00:11:18,350 --> 00:11:21,710
+لأغراض الاستثمار شو بيصير فيها يعني واحد تكلفة
+
+166
+00:11:21,710 --> 00:11:25,740
+الاقتراض نزلت عمليًا هيصيروا ناس يقبلوا القروض
+
+167
+00:11:25,740 --> 00:11:30,560
+وبالتالي حجم الاستثمارات هتزيد صح؟ So this leads
+
+168
+00:11:30,560 --> 00:11:40,560
+to increasing the size of borrowing إذا
+
+169
+00:11:40,560 --> 00:11:45,360
+شو اللي سيه؟ ال investment هيزيد صح؟ So this leads
+
+170
+00:11:45,360 --> 00:11:47,520
+to an increase of the aggregate investment
+
+171
+00:11:50,350 --> 00:11:53,930
+اللي هو ايش I شوفته ال formula تبعت ال aggregate
+
+172
+00:11:53,930 --> 00:12:01,270
+expenditure C plus I plus G plus X minus M رجعت ال
+
+173
+00:12:01,270 --> 00:12:07,170
+I زادت صح وبالتالي ال aggregate expenditure هيقعد
+
+174
+00:12:07,170 --> 00:12:13,070
+يزيد صح هي cycle هيك اذا هنا هذا هيزود ال
+
+175
+00:12:13,070 --> 00:12:18,550
+aggregate expenditure once again أو هنا في ال case
+
+176
+00:12:18,550 --> 00:12:20,930
+الأول في عندى decreasing كان في aggregate
+
+177
+00:12:20,930 --> 00:12:26,070
+expenditure اه هى decreasing في ال ..شوفوا دايما
+
+178
+00:12:26,070 --> 00:12:30,510
+في ال phase الأول في ال stage الأول الانخفاض هنا
+
+179
+00:12:30,510 --> 00:12:35,390
+أكبر من الارتفاع هنا ولو كان في عندى ارتفاع هنا
+
+180
+00:12:35,390 --> 00:12:40,810
+بيكون أكبر من الخفاض في المرحلة التانية مش واضحة
+
+181
+00:12:40,810 --> 00:12:44,550
+صح؟ يعني suppose التأثير في المرحلة الأولى اللى
+
+182
+00:12:44,550 --> 00:12:45,810
+علاقة بموضوع ال multiplier
+
+183
+00:12:49,360 --> 00:12:53,300
+دايمًا التأثير في المرحلة الأولى الانخفاض هنا صار
+
+184
+00:12:53,300 --> 00:12:56,320
+في المرحلة الأولى in the first stage في عندي 
+
+185
+00:12:56,320 --> 00:12:59,520
+decrease في ال aggregate اسم الدشار صح؟ لو روحنا
+
+186
+00:12:59,520 --> 00:13:02,600
+على التأثير بعد هيك على ال money market هنرجع لل
+
+187
+00:13:02,600 --> 00:13:05,640
+goods and services مرة تانية هيكون بالعكس هذا
+
+188
+00:13:05,640 --> 00:13:09,360
+هنجيره كمان شوية اسمه crowding out crowding in
+
+189
+00:13:09,360 --> 00:13:14,960
+crowding out crowding in لسه يعني هتعملنا ندخل على
+
+190
+00:13:14,960 --> 00:13:21,750
+الموضوع هذا ماشي؟ so as you see the income which is
+
+191
+00:13:21,750 --> 00:13:24,430
+determined in the goods and services market ايش
+
+192
+00:13:24,430 --> 00:13:30,890
+ماله؟ زا أو نقص؟ شو سؤالي؟ نقص ال money demand
+
+193
+00:13:30,890 --> 00:13:33,390
+decreased وبتاع ال interest rate decreased ال
+
+194
+00:13:33,390 --> 00:13:37,390
+investment رجع طلع مرة تانية أو increased ومن ثم
+
+195
+00:13:37,390 --> 00:13:41,390
+ال aggregate expenditure increased صح؟ طيب لو بدي
+
+196
+00:13:41,390 --> 00:13:46,530
+اروح على ايش تاني هنا هيك شو شكل العلاقة ما بين ال
+
+197
+00:13:46,530 --> 00:13:50,750
+interest rate و ال investment؟ Exactly negative So
+
+198
+00:13:50,750 --> 00:13:54,070
+we have a negative relationship بين مين ومين؟ بين
+
+199
+00:13:54,070 --> 00:13:57,330
+ال interest rate و ال investment When the interest rate
+
+200
+00:13:57,330 --> 00:14:02,210
+declined شو صار في ال investment؟ Increased نتيجة
+
+201
+00:14:02,210 --> 00:14:04,770
+من موضوع ال cost of borrowing اللي حكينا فيه تمام؟
+
+202
+00:14:04,770 --> 00:14:09,570
+So as you see in this curve This curve illustrates
+
+203
+00:14:09,570 --> 00:14:12,810
+the relationship between the interest rate و This
+
+204
+00:14:12,810 --> 00:14:20,480
+is R and the investment I هناك علاقة خاطئة بين قيمة
+
+205
+00:14:20,480 --> 00:14:24,740
+الدولة والاستثمار. إذا كانت قيمة الدولة .. على
+
+206
+00:14:24,740 --> 00:14:28,300
+سبيل المثال، هذا هو الوضع point A وB، فإن زيادة
+
+207
+00:14:28,300 --> 00:14:34,120
+قيمة الدولة من 6% إلى 9% يتسبب في تقليل الدولة
+
+208
+00:14:34,120 --> 00:14:41,320
+الدولية من I1 إلى I2. تمام؟ ومع ذلك، تقليل N أو R
+
+209
+00:14:41,320 --> 00:14:47,660
+يتسبب في زيادة الدولة الدولية. صعب الأمور؟ إيه؟ تمام
+
+210
+00:14:47,660 --> 00:14:50,900
+طيب
+
+211
+00:14:50,900 --> 00:14:57,840
+suppose that we started from the decrease or
+
+212
+00:14:57,840 --> 00:15:04,340
+increase in R as you see this diagram هذا الشكل
+
+213
+00:15:04,340 --> 00:15:06,500
+العلاقة بال goods and services market ولا في ال
+
+214
+00:15:06,500 --> 00:15:10,170
+money market طول ما بنحكي في .. exactly طول ما
+
+215
+00:15:10,170 --> 00:15:12,710
+بنحكي في government spending و aggregate
+
+216
+00:15:12,710 --> 00:15:15,330
+expenditure و هذا كله بنحكي في ايش؟ في ال goods
+
+217
+00:15:15,330 --> 00:15:18,850
+market، تمام؟ إذا أنا أرسم هاي إيه علاقة بال goods
+
+218
+00:15:18,850 --> 00:15:24,840
+market، تمام؟ طيب بدأ أشوف أنا إذا صار في عندي قرار
+
+219
+00:15:24,840 --> 00:15:28,140
+قد تُخذ في الـ money market يعني سببز إن إحنا
+
+220
+00:15:28,140 --> 00:15:30,720
+بدأنا في عندي increase في ال interest rate شو
+
+221
+00:15:30,720 --> 00:15:34,920
+تأثيره على ال goods market؟ هذا السؤال، إذا بدنا
+
+222
+00:15:34,920 --> 00:15:38,560
+نبدأ في إيش؟ في تحليل تأثير سياسة نقدية على سوق
+
+223
+00:15:38,560 --> 00:15:42,760
+البضاعة، هذا ما بدنا نفعل، so as you see suppose
+
+224
+00:15:42,760 --> 00:15:47,360
+that in the goods and services market
+
+225
+00:15:51,040 --> 00:15:56,500
+الأول أو الاتصال الاصطناعي كان في نقطة E1 هنا
+
+226
+00:16:00,420 --> 00:16:05,260
+هذا ايش؟ this is Y فاكرينوا هذا وهذا this is the
+
+227
+00:16:05,260 --> 00:16:08,380
+aggregate expenditure بتسمي aggregate expenditure
+
+228
+00:16:08,380 --> 00:16:13,080
+one يعني aggregate expenditure one اللي هو C plus
+
+229
+00:16:13,080 --> 00:16:18,180
+I plus G plus X minus M بلاش نتعامل معاهم هلقيت
+
+230
+00:16:18,180 --> 00:16:22,720
+مبدئيًا we are talking about C I G و I بتفترضها I
+
+231
+00:16:22,720 --> 00:16:27,420
+not تمام؟ so we have Y
+
+232
+00:16:31,490 --> 00:16:39,350
+و aggregate expenditure one تمام؟ where is the
+
+233
+00:16:39,350 --> 00:16:42,390
+equilibrium؟ ال equilibrium قلنا يحدث لما يكون فيه
+
+234
+00:16:42,390 --> 00:16:44,130
+intersection ما بين ال Y و ال aggregate
+
+235
+00:16:44,130 --> 00:16:46,990
+expenditure صح؟ مش هتاخدناه في ال chapter اللي
+
+236
+00:16:46,990 --> 00:16:51,670
+قبله؟ تمام now suppose أن the central bank
+
+237
+00:16:51,670 --> 00:16:56,010
+decided to increase the interest rate suppose أن
+
+238
+00:16:56,010 --> 00:16:59,090
+the central bank decided to increase the interest
+
+239
+00:16:59,090 --> 00:17:03,530
+rate شو بيسوي .. شو بيصير في ال investment؟ هيقل ..
+
+240
+00:17:03,530 --> 00:17:06,630
+هيقل because we have an inverse relationship
+
+241
+00:17:06,630 --> 00:17:13,430
+between R and I so I would decline طب شو بيصير في
+
+242
+00:17:13,430 --> 00:17:17,770
+ال aggregate expenditure؟ بسبب أن I هو المستخدم
+
+243
+00:17:17,770 --> 00:17:22,130
+المستخدم المستخدم المستخدم المستخدم المستخدم
+
+244
+00:17:22,130 --> 00:17:25,190
+المستخدم المستخدم المستخدم المستخدم المستخدم
+
+245
+00:17:25,190 --> 00:17:28,590
+المستخدم المستخدم المستخدم المستخدم المستخدم
+
+246
+00:17:28,590 --> 00:17:29,390
+المستخدم المستخدم المستخدم المستخدم المستخدم
+
+247
+00:17:29,390 --> 00:17:31,730
+المستخدم المستخدم المستخدم المستخدم المستخدم
+
+248
+00:17:31,730 --> 00:17:34,830
+المستخدم المستخدم المستخدم المستخدم المستخدم
+
+249
+00:17:34,830 --> 00:17:39,190
+المستخدم المستخدم المستخدم المستخدم المستخدم
+
+250
+00:17:39,190 --> 00:17:39,350
+المستخدم المستخدم المستخدم المستخدم المستخدم
+
+251
+00:17:39,350 --> 00:17:42,750
+المستخدم المستخدم المستخدم المست
+
+252
+00:17:46,180 --> 00:17:51,560
+the aggregate expenditure function نزلت بمقدار ايش؟
+
+253
+00:17:51,560 --> 00:17:57,800
+بمقدار النزول في الـ I صح؟ القيمة اللي نزلت في ال
+
+254
+00:17:57,800 --> 00:18:00,000
+aggregate expenditure هذا من aggregate expenditure
+
+255
+00:18:00,000 --> 00:18:07,200
+1 ل aggregate expenditure 2 equals C plus I1 plus
+
+256
+00:18:07,200 --> 00:18:13,890
+G نزلت الـ aggregate expenditure في الـ I نزلت الـ
+
+257
+00:18:13,890 --> 00:18:19,430
+A2 نزلت
+
+258
+00:18:19,430 --> 00:18:26,550
+الـ A2
+
+259
+00:18:26,550 --> 00:18:29,890
+نزلت
+
+260
+00:18:29,890 --> 00:18:36,530
+الـ A2 نزلت الـ A2 نزلت الـ A2 نزلت الـ A2 نزلت
+
+261
+00:18:36,530 --> 00:18:37,230
+الـ A2 نزلت الـ A2 نزلت الـ A2 نزلت الـ A2 نزلت
+
+262
+00:18:37,230 --> 00:18:37,910
+الـ A2 نزلت الـ A2 نزلت الـ A2 نزلت الـ A2 نزلت
+
+263
+00:18:38,290 --> 00:18:47,570
+صارت عند وين؟ Y1 from Y0 to Y1 so the decrease
+
+264
+00:18:47,570 --> 00:18:51,170
+in aggregate expenditure leads to what؟ a
+
+265
+00:18:51,170 --> 00:19:00,730
+decrease in Y from Y0 to Y1 that's it شفتوا؟ صعب
+
+266
+00:19:00,730 --> 00:19:05,190
+الأمور؟ كمان شوية هنروح منها على وين نرجع برجوع على
+
+267
+00:19:05,190 --> 00:19:08,970
+ال money market يعني لو بدأ أستكمل السلسلة هيك the
+
+268
+00:19:08,970 --> 00:19:11,250
+decrease في ال aggregate output شو بيسوي في ال
+
+269
+00:19:11,250 --> 00:19:14,310
+income؟ بنزل وبتاع ال money demand would decline
+
+270
+00:19:14,310 --> 00:19:20,560
+and so on it's a cycle تمام؟ yes اه constant
+
+271
+00:19:20,560 --> 00:19:24,520
+exactly يعني احنا بنفترض أن في عندي decrease في
+
+272
+00:19:24,520 --> 00:19:27,060
+ال I أو ال R أثر على ال I ما تأثرش على ال C
+
+273
+00:19:27,060 --> 00:19:30,780
+وما تأثرش على ال G وبالتالي ال C and G remain
+
+274
+00:19:30,780 --> 00:19:37,080
+constant تمام طيب and vice versa suppose أن this
+
+275
+00:19:37,080 --> 00:19:41,560
+is aggregate expenditure one وصار في عندنا
+
+276
+00:19:43,060 --> 00:19:45,860
+decrease في ال interest rate يعني suppose أن
+
+277
+00:19:45,860 --> 00:19:48,620
+العملية معاكسة لما في عندك decrease في ال R شو
+
+278
+00:19:48,620 --> 00:19:52,600
+بتعمل في ال investment؟ increase I وبالتالي
+
+279
+00:19:52,600 --> 00:19:55,380
+increasing the aggregate expenditure ومن ثم ال
+
+280
+00:19:55,380 --> 00:19:59,100
+aggregate demand this leads to increasing Y from Y
+
+281
+00:19:59,100 --> 00:20:03,100
+naught to Y one يعني لو بدأ افترض أن في تغيير هيك
+
+282
+00:20:03,100 --> 00:20:06,960
+هذا Y naught Y one aggregate expenditure one to
+
+283
+00:20:06,960 --> 00:20:12,460
+aggregate expenditure two صعبة الأمور؟ مين عنده طب
+
+284
+00:20:12,460 --> 00:20:21,200
+مشكلة؟ مين أعيد له طيب؟ تفضل تمام في ال case الأول؟
+
+285
+00:20:21,200 --> 00:20:24,840
+ماله؟ نزلت طب آه نزلت okay وبالتالي في عنده
+
+286
+00:20:24,840 --> 00:20:30,040
+decreasing لأ decreasing هي لأن this is هي ال
+
+287
+00:20:30,040 --> 00:20:32,840
+aggregate .. وين ال autonomous ال autonomous
+
+288
+00:20:32,840 --> 00:20:35,900
+aggregate expenditure وين بيكون في البداية اللي
+
+289
+00:20:35,900 --> 00:20:38,360
+بتفترض هذا 150 يعني suppose أن ال aggregate
+
+290
+00:20:38,360 --> 00:20:40,860
+expenditure function aggregate expenditure
+
+291
+00:20:40,860 --> 00:20:47,120
+function الأولى كانت 150 plus 7 من 10 Y مش هي ال
+
+292
+00:20:47,120 --> 00:20:50,620
+.. ال .. ال function هاي لنزول في ال aggregate
+
+293
+00:20:50,620 --> 00:20:53,900
+expenditure أو في ال I شو .. خليها 100 هذا صراحة
+
+294
+00:20:59,330 --> 00:21:03,990
+صح؟ وين ال autonomous يعني سبق أن هذا كان 150 ال
+
+295
+00:21:03,990 --> 00:21:07,390
+autonomous aggregate expenditure الانزول في ال
+
+296
+00:21:07,390 --> 00:21:10,610
+planned investment يعني لو ال plan I نزلت يعني
+
+297
+00:21:10,610 --> 00:21:13,250
+اللي هي I ال aggregate expenditure عبارة عن إيش C
+
+298
+00:21:13,250 --> 00:21:19,230
+plus I مصبوط plus G الانزول في قيمة ال autonomous
+
+299
+00:21:19,230 --> 00:21:22,130
+I هذا بنزل هذا من 150 ل 100 مثلا
+
+300
+00:21:25,520 --> 00:21:31,840
+which one لازم لازم يتحرك لأنه لحظة لحظة لحظة لحظة
+
+301
+00:21:31,840 --> 00:21:34,480
+هلأ ال aggregate expenditure function mainly ايش
+
+302
+00:21:34,480 --> 00:21:39,420
+بتساوي ال C plus I plus G تمام؟ بدي أرجع لك ل
+
+303
+00:21:39,420 --> 00:21:45,420
+chapter 4 أظن أن أو 4 أو 5 suppose كانت أن ال
+
+304
+00:21:45,420 --> 00:21:49,340
+aggregate أو ال consumption function equals 100
+
+305
+00:21:49,340 --> 00:22:03,390
+plus 0.7Y صح؟ وقال لك أن الـ I equals 20 أو 50 how
+
+306
+00:22:03,390 --> 00:22:06,070
+much is the aggregate expenditure function when
+
+307
+00:22:06,070 --> 00:22:09,650
+there is no government افرض فيش government قديش ال
+
+308
+00:22:09,650 --> 00:22:11,970
+aggregate expenditure function aggregate
+
+309
+00:22:11,970 --> 00:22:16,310
+expenditure function اللي هي C plus I right مظبوط
+
+310
+00:22:16,310 --> 00:22:21,230
+طيب إذا ال aggregate expenditure equals C 100 plus
+
+311
+00:22:21,230 --> 00:22:27,250
+0.7Y plus I 50 so aggregate expenditure شو بتساوي
+
+312
+00:22:27,250 --> 00:22:34,300
+150 plus 0.7Y صح؟ لو قال لك أن suppose أن ال
+
+313
+00:22:34,300 --> 00:22:37,880
+investment ل planned investment نزل لأن نتيجة أن
+
+314
+00:22:37,880 --> 00:22:41,940
+ال interest راح يطلع تمام
+
+315
+00:22:41,940 --> 00:22:48,080
+مثلا يعني suppose أن ال I declined
+
+316
+00:22:48,080 --> 00:22:54,580
+to 20 بدل ما هو 50 صار عشرين تمام أنا لو ده نيجي
+
+317
+00:22:54,580 --> 00:22:59,470
+نعمل deriving لل function هذه أو نرسمها هيكون هذا
+
+318
+00:22:59,470 --> 00:23:04,010
+هيك وهذا 150 وهذا سيكون في ميلته 7 من 10 مظبوط؟
+
+319
+00:23:04,010 --> 00:23:07,150
+طيب لو أنا أجيب و أعمل deriving لل aggregate
+
+320
+00:23:07,150 --> 00:23:11,110
+expenditure function الجديد لل new بيصير عندي ايش؟
+
+321
+00:23:11,110 --> 00:23:14,630
+ال aggregate expenditure الجديد الثاني شو بتساوي؟
+
+322
+00:23:14,630 --> 00:23:19,310
+the same هذا بس ناقص ال I أو اللي هو المقدار اللي
+
+323
+00:23:19,310 --> 00:23:24,330
+نزل بال I مظبوط؟ صح؟ شو بيصير عندي؟ أو C plus I
+
+324
+00:23:24,330 --> 00:23:29,870
+يعني ايه المعادلة؟ C plus I Equals aggregate
+
+325
+00:23:29,870 --> 00:23:37,030
+expenditure 2 بيساوي الـ C عند قداش هي 100 زائد 7
+
+326
+00:23:37,030 --> 00:23:45,090
+من 10 Y زائد ال I نزلت لقداش ل 20 So aggregate
+
+327
+00:23:45,090 --> 00:23:51,170
+expenditure 2 يساوي 120 plus 7 من 10 Y إذا هدا عند
+
+328
+00:23:51,170 --> 00:24:00,100
+150 وهدا هتكون عند 120 وضحت ولا ما وضحتش آه يعني
+
+329
+00:24:00,100 --> 00:24:02,720
+الجد هتلاقي و كل ال chapters مربوطة ببعضها مربوطة
+
+330
+00:24:02,720 --> 00:24:07,140
+بهذا و ال chapter هذا مربوط في اللي بعده ماشي طيب
+
+331
+00:24:07,140 --> 00:24:12,160
+إذا vice versa أن إذا كان في عندي decreasing في
+
+332
+00:24:12,160 --> 00:24:15,660
+ال R بيزود ال investment و من ثم ال aggregate
+
+333
+00:24:15,660 --> 00:24:18,920
+expenditure would increase و I would increase and
+
+334
+00:24:18,920 --> 00:24:19,240
+so on
+
+335
+00:24:23,640 --> 00:24:27,900
+تمام بس when we analyze the economics theory the
+
+336
+00:24:27,900 --> 00:24:32,180
+economics phenomena we assume that all of other
+
+337
+00:24:32,180 --> 00:24:35,800
+factors remain constant يعني بنفترض .. بصير يعني
+
+338
+00:24:35,800 --> 00:24:38,940
+أن عندك .. يكون في عندك تغيير في أكثر من تمام
+
+339
+00:24:38,940 --> 00:24:42,940
+تمام بس لما بحلل أنا بفترض أن بدرس علاقة بين two
+
+340
+00:24:42,940 --> 00:24:45,900
+variables و بفترض بجهة المتغيرات ثابتة وإن كان مش
+
+341
+00:24:45,900 --> 00:24:48,800
+منطقي لكن هي التحليل هيك to .. to .. to control
+
+342
+00:24:48,800 --> 00:24:49,780
+the analysis
+
+343
+00:24:52,360 --> 00:24:55,800
+تبدأ تحلل تأثيرات كلهم لو كان كل .. يعني صار في
+
+344
+00:24:55,800 --> 00:24:59,500
+عندي أن هذا ال investment زاد نزل ب 10% و ال
+
+345
+00:24:59,500 --> 00:25:03,620
+consumption increased ب 20% و هذا زاد ب 30% so you
+
+346
+00:25:03,620 --> 00:25:07,840
+have to analyze the final result on the aggregate
+
+347
+00:25:07,840 --> 00:25:11,560
+expenditure exactly يعني هذا .. بس التحليل البسيط
+
+348
+00:25:11,560 --> 00:25:19,100
+بدي أخد كل واحد لحاله تمام؟ طيب so let's go
+
+349
+00:25:27,560 --> 00:25:32,400
+إذن عشان أدرس تأثير القرار اللي تُخذ the effect of
+
+350
+00:25:32,400 --> 00:25:35,240
+the decision that has been taken in the money
+
+351
+00:25:35,240 --> 00:25:37,900
+market بتشوف تأثيره على ال goods and services
+
+352
+00:25:37,900 --> 00:25:43,400
+market as you see the
+
+353
+00:25:43,400 --> 00:25:46,840
+increasing in interest rate leads to a decreasing
+
+354
+00:25:46,840 --> 00:25:50,920
+in I decreasing in aggregate expenditure and then
+
+355
+00:25:52,620 --> 00:25:56,740
+decreasing in Y, Y is the aggregate output, تمام؟
+
+356
+00:25:56,740 --> 00:25:59,280
+هذا شو تأثيره على ال .. ال .. ال income, the
+
+357
+00:25:59,280 --> 00:26:05,020
+aggregate income؟ the decreasing in Y leads to a
+
+358
+00:26:05,020 --> 00:26:10,300
+decreasing in aggregate income طب شو بسبب ال money
+
+359
+00:26:10,300 --> 00:26:14,240
+demand هذا؟ exactly, so this leads to a decreasing
+
+360
+00:26:14,240 --> 00:26:19,240
+in money demand So we have a leftward shifting in
+
+361
+00:26:19,240 --> 00:26:22,080
+money demand curve يعني لو بدي أعمل رسمة هيك هذه
+
+362
+00:26:22,080 --> 00:26:28,660
+الرسمة ما بتعكس الشغل تبعنا this
+
+363
+00:26:28,660 --> 00:26:34,340
+is RQM ما بتحكي في الرسمة هذه نركزوا في الرسمة
+
+364
+00:26:34,340 --> 00:26:38,780
+هذه money
+
+365
+00:26:38,780 --> 00:26:47,730
+demand one money supply one E one R1 تمام and this
+
+366
+00:26:47,730 --> 00:26:52,530
+is QM1 as you see the decreasing in income the
+
+367
+00:26:52,530 --> 00:26:54,770
+aggregate income leads to a decreasing in money
+
+368
+00:26:54,770 --> 00:26:58,810
+demand وبتالي there is what a leftward shifting في
+
+369
+00:26:58,810 --> 00:27:02,030
+ال money demand curve صح إذا هنيجي من في ال money
+
+370
+00:27:02,030 --> 00:27:05,270
+demand curve هنعمل leftward shifting في ال money
+
+371
+00:27:05,270 --> 00:27:11,370
+demand curve to MD2 شو بعمل في ال interest rate
+
+372
+00:27:15,270 --> 00:27:22,130
+صح؟ this is E2 ومن ثم شو بيحصل في ال investment؟
+
+373
+00:27:22,130 --> 00:27:27,950
+so this leads to decreasing interest rate and
+
+374
+00:27:27,950 --> 00:27:34,210
+increasing which leads to increasing in I بس هذا
+
+375
+00:27:34,210 --> 00:27:38,370
+وين؟ بيكون smaller than the previous case or the
+
+376
+00:27:38,370 --> 00:27:41,850
+previous stage يعني لو زاد هنا ال investment ب 20%
+
+377
+00:27:43,080 --> 00:27:45,980
+هنا النزول في ال investment ممكن يكون خمسة في
+
+378
+00:27:45,980 --> 00:27:51,120
+المية سبعة في المية أن ده second stage صح؟ طب هذا
+
+379
+00:27:51,120 --> 00:27:56,780
+وين بوديني؟ أو increasing في ال I شو بيعمل؟ بيعمل
+
+380
+00:27:56,780 --> 00:28:01,460
+increasing في ال aggregate expenditure صح؟ بس برضه
+
+381
+00:28:01,460 --> 00:28:07,870
+small لأنه نسبة التأثير هنا أقل صح يعني هنا صار في
+
+382
+00:28:07,870 --> 00:28:10,830
+عنده ايش decreasing في ال aggregate expenditure
+
+383
+00:28:10,830 --> 00:28:15,630
+سببوز أن زاد أو decrease ب 20% هذا في مرحلة
+
+384
+00:28:15,630 --> 00:28:24,210
+second stage هينزل أو هيزيد بمثلا 5% تمام إذا أنا
+
+385
+00:28:24,210 --> 00:28:27,810
+بدي أرجع كمان مرة once again على ال goods market
+
+386
+00:28:27,810 --> 00:28:29,250
+هلاقي شو اللي صار عندي
+
+387
+00:28:33,370 --> 00:28:36,690
+شايفين شو اللي صار؟ يعني suppose أن من البداية
+
+388
+00:28:36,690 --> 00:28:38,790
+صار في عنده increasing في ال aggregate expenditure
+
+389
+00:28:38,790 --> 00:28:43,050
+بيزود ال aggregate aggregate income أو aggregate
+
+390
+00:28:43,050 --> 00:28:46,330
+output بعدين بعود بنزل مرة ثانية بحاجة بسيطة هذا
+
+391
+00:28:46,330 --> 00:28:50,230
+هنأخذه إن شاء الله in this class يعطيكم العافية
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/XN3gl_NJdMw.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/XN3gl_NJdMw.srt
new file mode 100644
index 0000000000000000000000000000000000000000..822621872be4fe58102d89bcccfc4bdf590b0e55
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/XN3gl_NJdMw.srt
@@ -0,0 +1,1515 @@
+1
+00:00:20,750 --> 00:00:24,710
+بسم الله الرحمن الرحيم اليوم إن شاء الله سنكمل
+
+2
+00:00:24,710 --> 00:00:32,990
+حديثنا عن الانتاج والانتاج وانفلات وانتاج
+
+3
+00:00:32,990 --> 00:00:33,230
+وانتاج وانتاج وانتاج وانتاج وانتاج وانتاج
+
+4
+00:00:33,230 --> 00:00:33,330
+وانتاج وانتاج وانتاج وانتاج وانتاج وانتاج
+
+5
+00:00:33,330 --> 00:00:33,730
+وانتاج وانتاج وانتاج وانتاج وانتاج وانتاج
+
+6
+00:00:33,730 --> 00:00:33,750
+وانتاج وانتاج وانتاج وانتاج وانتاج وانتاج
+
+7
+00:00:33,750 --> 00:00:34,030
+وانتاج وانتاج وانتاج وانتاج وانتاج وانتاج
+
+8
+00:00:34,030 --> 00:00:43,410
+وانتاج وانتاج وانتاج وانتاج وانتاج وانتاج
+
+9
+00:00:52,190 --> 00:00:56,970
+كما ذكرت أننا سنركز على ثلاثة أنواع من الانتاج
+
+10
+00:00:56,970 --> 00:01:02,950
+الأول هو الانتاج الفرخي الأول هو الانتاج الفرخي
+
+11
+00:01:02,950 --> 00:01:09,850
+الأول هو الانتاج الفرخي الانتاج الفرخي الانتاج 
+
+12
+00:01:09,850 --> 00:01:10,930
+الفرخي
+
+13
+00:01:13,020 --> 00:01:18,560
+means or occurs when the worker wants to leave his
+
+14
+00:01:18,560 --> 00:01:23,930
+work and to get another job or a better job لذلك
+
+15
+00:01:23,930 --> 00:01:31,170
+إذا ترك العامل عمله، فسينتظر عدة أسابيع ليجد عمل
+
+16
+00:01:31,170 --> 00:01:37,890
+آخر أو عمل أفضل، صح؟ لذلك في هذا الوقت أو في هذه
+
+17
+00:01:37,890 --> 00:01:43,330
+الأسابيع أو في هذه الأسابيع، يجب أن يتحسن مهارته 
+
+18
+00:01:43,330 --> 00:01:50,120
+لتناسب أو لتناسب المطالبات للعمل الجديد هذا الوقت
+
+19
+00:01:50,120 --> 00:01:53,100
+يسمى كتابة الانتاج الصحيح، لذلك الانتاج الصحيح
+
+20
+00:01:53,100 --> 00:01:57,440
+ليس سيئًا لعالم الاقتصاد لأنه عندما يرغب في تغيير
+
+21
+00:01:57,440 --> 00:02:02,260
+أو تغيير عمله من عمل لعمل آخر يجب أن يتحسن، يريد
+
+22
+00:02:02,260 --> 00:02:11,380
+أن يتحسن أو الانتاج سيزداد وهو كما ذكرت يريد
+
+23
+00:02:11,380 --> 00:02:15,720
+الحصول على عمل أفضل، لذلك والوقت يجب أن يكون
+
+24
+00:02:15,720 --> 00:02:16,840
+قصيرًا 
+
+25
+00:02:22,420 --> 00:02:32,260
+البطالة الهيكلية هي أكثر
+
+26
+00:02:32,260 --> 00:02:37,440
+مشكلة في الاقتصاد التي تحدث عندما .. أو كما ترى في
+
+27
+00:02:37,440 --> 00:02:42,060
+التصميم، الانتاج الأساسي هو جزء من الانتاج الذي
+
+28
+00:02:42,060 --> 00:02:47,760
+يسبب تغيير في أسلوب الاقتصاد الذي يسبب في فقدرة 
+
+29
+00:02:47,760 --> 00:02:50,900
+عمليات مهمة في بعض الانتاجات.
+
+30
+00:02:52,840 --> 00:02:59,160
+انتاج يرغب في تغيير أو .. انتاج يتغير في 
+
+31
+00:02:59,160 --> 00:03:03,950
+الانتاج، من الزراعية إلى الانتاج.القطاع عندنا
+
+32
+00:03:03,950 --> 00:03:07,650
+الدولة و البلد بدأت تتغير بتتحول من القطاع من
+
+33
+00:03:07,650 --> 00:03:12,070
+التركيز على القطاع الزراعي لقطاع صناعي So in this
+
+34
+00:03:12,070 --> 00:03:15,810
+case we have a structural change in the economy So
+
+35
+00:03:15,810 --> 00:03:19,750
+all the farmers or the people who works or work
+
+36
+00:03:19,750 --> 00:03:24,410
+in the agricultural sector will lose their jobs
+
+37
+00:03:24,410 --> 00:03:30,590
+right هذا هو الفكرة وبتالي هي مشكلة كبيرة أنه إذا
+
+38
+00:03:30,590 --> 00:03:34,050
+الـstructure تبع الـ economy it has been changed in
+
+39
+00:03:34,050 --> 00:03:36,950
+this case all the people who works in this sector
+
+40
+00:03:36,950 --> 00:03:42,270
+will lose their job and it will prolong for a deep
+
+41
+00:03:42,270 --> 00:03:47,070
+or for a long term or yes for a long period right
+
+42
+00:03:47,070 --> 00:03:55,190
+تمام؟ because it needs أعوامًا لتناسب مطالبات جديدة
+
+43
+00:03:55,190 --> 00:04:03,210
+لتغيير الاقتصاد المشروع في الاقتصاد المشروع في
+
+44
+00:04:03,210 --> 00:04:04,010
+الاقتصاد المشروع في الاقتصاد المشروع في الاقتصاد
+
+45
+00:04:04,010 --> 00:04:04,350
+المشروع في الاقتصاد المشروع في الاقتصاد المشروع
+
+46
+00:04:04,350 --> 00:04:05,230
+في الاقتصاد المشروع في الاقتصاد المشروع في
+
+47
+00:04:05,230 --> 00:04:05,710
+الاقتصاد المشروع في الاقتصاد المشروع في الاقتصاد
+
+48
+00:04:05,710 --> 00:04:06,510
+في الاقتصاد المشروع في الاقتصاد المشروع في
+
+49
+00:04:06,510 --> 00:04:10,670
+الاقتصاد المشروع في الاقتصاد المشروع في الاقتصاد
+
+50
+00:04:10,670 --> 00:04:19,110
+المشروع في الاقتصاد المشروع في الاقتص
+
+51
+00:04:25,320 --> 00:04:30,380
+كما تعلمين ما كان هذا؟ هذا هو
+
+52
+00:04:30,380 --> 00:04:36,480
+عملية العمل نعم و في عملية العمل نحن لدينا تغيير
+
+53
+00:04:36,480 --> 00:04:46,920
+من أعلى إلى أسفل نحن لدينا ماذا؟ اتخاذ في المصادر
+
+54
+00:04:48,110 --> 00:04:49,990
+أو عادة أو عادة أو عادة أو عادة أو عادة أو عادة أو
+
+55
+00:04:49,990 --> 00:04:54,810
+عادة أو عادة أو عادة أو عادة أو عادة أو عادة أو
+
+56
+00:04:54,810 --> 00:05:01,810
+عادة أو عادة أو عادة أو عادة أو عادة أو عادة أو
+
+57
+00:05:01,810 --> 00:05:02,430
+عادة أو عادة أو عادة أو عادة أو عادة أو عادة أو
+
+58
+00:05:02,430 --> 00:05:02,850
+عادة أو عادة أو عادة أو عادة أو عادة أو عادة أو
+
+59
+00:05:02,850 --> 00:05:03,790
+عادة أو عادة أو عادة أو عادة أو عادة أو عادة أو
+
+60
+00:05:03,790 --> 00:05:03,970
+عادة أو عادة أو عادة أو عادة أو عادة أو عادة أو
+
+61
+00:05:03,970 --> 00:05:05,810
+عادة أو عادة أو عادة أو عادة أو عادة أو عادة أو
+
+62
+00:05:05,810 --> 00:05:06,630
+عادة أو عادة أو عادة أو عادة أو عادة أو عادة أو
+
+63
+00:05:06,630 --> 00:05:11,350
+عادة أو 
+
+64
+00:05:11,350 --> 00:05:11,370
+عاد
+
+65
+00:05:14,390 --> 00:05:17,410
+وهو ما يسمى كاملًا كاملًا كاملًا كاملًا كاملًا
+
+66
+00:05:17,410 --> 00:05:39,810
+كاملًا كاملًا كاملًا كاملًا كاملًا
+
+67
+00:05:40,250 --> 00:05:43,090
+و في هذا الوقت، ستتخلص من نسبة الـ GDP أو نسبة الـ
+
+68
+00:05:43,090 --> 00:05:53,470
+Gross Output نسبة
+
+69
+00:05:53,470 --> 00:05:56,850
+الـ GDP أو نسبة الـ Gross Output نسبة الـ GDP أو
+
+70
+00:05:56,850 --> 00:05:57,550
+نسبة الـ Gross Output نسبة الـ GDP أو نسبة الـ
+
+71
+00:05:57,550 --> 00:05:57,650
+أو نسبة الـ Grass Output نسبة الـ Grass Output
+
+72
+00:05:57,650 --> 00:06:03,930
+نسبة الـ Grass Output نسبة الـ Grass Output نسبة
+
+73
+00:06:03,930 --> 00:06:13,200
+الـ Grass Output في كل دولة في العالم لتجد أن 
+
+74
+00:06:13,200 --> 00:06:26,880
+قيمة الانتاج صحيحة صحيحة صحيحة
+
+75
+00:06:26,880 --> 00:06:32,740
+صحيحة صحيحة
+
+76
+00:06:32,740 --> 00:06:35,740
+صحيحة
+
+77
+00:06:40,640 --> 00:06:42,840
+والاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+78
+00:06:42,840 --> 00:06:46,880
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+79
+00:06:46,880 --> 00:06:50,920
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+80
+00:06:50,920 --> 00:06:55,020
+الاستخدام الاستخدام
+
+81
+00:06:55,020 --> 00:06:58,440
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+82
+00:06:58,440 --> 00:06:58,520
+الاستخدام الاستخدام الاستخدام الاستخدام الاستخدام
+
+83
+00:06:58,520 --> 00:07:00,620
+الاستخدم الاستخدم الاستخدم الاستخدام الاستخدام
+
+84
+00:07:00,620 --> 00:07:05,760
+الاستخدم
+
+85
+00:07:05,760 --> 00:07:14,980
+الاستخدام الاستEquals 4% Calculate the natural rate
+
+86
+00:07:14,980 --> 00:07:17,740
+of unemployment الوضع المعدل الطبيعي للبطالة في
+
+87
+00:07:17,740 --> 00:07:23,820
+الحياة Equals the summation 2% plus 4% equals 6%
+
+88
+00:07:23,820 --> 00:07:27,620
+This is the natural rate of unemployment So let's
+
+89
+00:07:27,620 --> 00:07:31,500
+come back to the definition as you see The natural
+
+90
+00:07:31,500 --> 00:07:33,860
+rate of unemployment is the unemployment that
+
+91
+00:07:33,860 --> 00:07:37,140
+occurs as a normal part of the functioning of the
+
+92
+00:07:37,140 --> 00:07:41,980
+economy و في بعض الأحيان تم اختيارها كصميمة من
+
+93
+00:07:41,980 --> 00:07:46,740
+الانتاج الانتاجي كمجموعة بطالة احتكاكية زي
+
+94
+00:07:46,740 --> 00:07:51,060
+البطالة الهيكلية بيعطينا شو؟ بطالة انتاج
+
+95
+00:07:51,060 --> 00:07:58,240
+الانتاج الانتاجي و كما ترى أنها بين 4 و 6 أشخاص،
+
+96
+00:07:58,240 --> 00:08:07,690
+صحيح؟ حسنا المفاتيح من الانتاج كما تعلمين، في وقت
+
+97
+00:08:07,690 --> 00:08:14,090
+الانتقال، لدينا عدد عملية عملية عملية عملية عملية
+
+98
+00:08:14,090 --> 00:08:15,310
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+99
+00:08:15,310 --> 00:08:19,950
+عملية عملية
+
+100
+00:08:19,950 --> 00:08:24,470
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+101
+00:08:24,470 --> 00:08:24,770
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+102
+00:08:24,770 --> 00:08:25,130
+عملية عملية عملية عملية عملية عملية عملية عملية
+
+103
+00:08:25,130 --> 00:08:31,510
+عملية عملية عملية عملية عمل
+
+104
+00:08:31,750 --> 00:08:35,110
+لذلك إذا كان لدينا اتفاق قليل أو اتفاق كبير
+
+105
+00:08:35,110 --> 00:08:39,550
+للأشياء، فالسعر سيكون كم؟ ستتخلص، لذلك في تجارب
+
+106
+00:08:39,550 --> 00:08:45,670
+التجارب، لذلك تجارب التجارب ليست دائمًا سيئة لأن
+
+107
+00:08:45,670 --> 00:08:49,290
+في بعض الأحيان في تجارب التجارب، السعر ستتخلص،
+
+108
+00:08:49,290 --> 00:08:53,250
+لذلك إنه بسهولة للشركة المشتركة أنها ستزال تزال
+
+109
+00:08:53,250 --> 00:08:55,950
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+110
+00:08:55,950 --> 00:08:58,150
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+111
+00:08:58,150 --> 00:08:59,370
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+112
+00:08:59,370 --> 00:08:59,870
+تزال تزال تزال تزال تزال تزال تزال تزال تزال تزال
+
+113
+00:08:59,870 --> 00:09:02,230
+تزال تزال
+
+114
+00:09:04,660 --> 00:09:09,540
+نعم، نحن نتفاق بأننا في تجارب التجارب، نحن نحصل
+
+115
+00:09:09,540 --> 00:09:13,940
+على عدد عملي عالي، نحن نحصل على تجارب التجارب التي
+
+116
+00:09:13,940 --> 00:09:19,660
+تتخلص منها، وهناك مطالبة صغيرة أو ضعيفة للعمل،
+
+117
+00:09:19,660 --> 00:09:25,280
+ولكن نحن نحصل على بعض المفاتيح من تجارب التجارب،
+
+118
+00:09:25,280 --> 00:09:30,160
+وهي أن السعر في تجارب التجارب، السعر للمواد
+
+119
+00:09:30,160 --> 00:09:38,890
+المختلفة تتخلص منها، ماذا آخر؟ الشركات ستتنقل لأننا 
+
+120
+00:09:38,890 --> 00:09:42,530
+لدينا بالفعل تتعامل بشركات تتعامل بتعامل بتعامل
+
+121
+00:09:42,530 --> 00:09:44,270
+بتعامل بتعامل بتعامل بتعامل بتعامل بتعامل بتعامل
+
+122
+00:09:44,270 --> 00:09:48,290
+بتعامل بتعامل بتعامل
+
+123
+00:09:48,290 --> 00:09:55,470
+بتعامل بتعامل بتعامل بتعامل بتعامل بتعامل بتعامل
+
+124
+00:09:55,470 --> 00:09:56,130
+بتعامل بتعامل بتعامل بتعامل بتعامل بتعامل بتعامل
+
+125
+00:09:56,130 --> 00:09:59,030
+بتعامل بتعامل بتعامل بتعامل بتعامل بتعامل بتعامل
+
+126
+00:09:59,030 --> 00:10:01,630
+بتعام
+
+127
+00:10:12,410 --> 00:10:23,070
+السعر يزال يزال يزال يزال يزال يزال
+
+128
+00:10:23,070 --> 00:10:25,330
+يزال
+
+129
+00:10:26,830 --> 00:10:30,410
+Okay it's .. it's .. it's .. it's logical because
+
+130
+00:10:30,410 --> 00:10:33,450
+increasing the prices for sure the demand for the
+
+131
+00:10:33,450 --> 00:10:36,810
+products is .. will be low Okay
+
+132
+00:10:42,610 --> 00:10:46,170
+Okay here we are talking about the different types
+
+133
+00:10:46,170 --> 00:10:50,490
+of inflation As
+
+134
+00:10:50,490 --> 00:10:54,490
+you know most of the products enter the Gaza Strip
+
+135
+00:10:54,490 --> 00:10:59,250
+are imported through the tunnels through across
+
+136
+00:10:59,250 --> 00:11:04,170
+checkpoints or across right? So it's called
+
+137
+00:11:04,170 --> 00:11:11,200
+importing inflation أو تضخم مستورد اصلا تضخم مستورد
+
+138
+00:11:11,200 --> 00:11:17,360
+لذلك عندما نتحدث عن .. أو الانتاجات تظهر أن أكثر
+
+139
+00:11:17,360 --> 00:11:25,100
+من 97 من خارج .. أو خارج خياراتنا .. 90 .. أكثر من
+
+140
+00:11:25,100 --> 00:11:31,420
+97 من خارج خياراتنا with Israel so if we imported
+
+141
+00:11:31,420 --> 00:11:34,680
+goods
+
+142
+00:11:34,680 --> 00:11:37,380
+and services from Israel for sure if the prices in
+
+143
+00:11:37,380 --> 00:11:41,140
+Israel increase, in this case we will or the
+
+144
+00:11:41,140 --> 00:11:44,440
+inflation will be transferred to Gaza for sure
+
+145
+00:11:44,440 --> 00:11:48,780
+direct, so it's called imported inflation أداة ضخمة
+
+146
+00:11:48,780 --> 00:11:51,600
+مستورد جايبينه معانا من برا yes
+
+147
+00:11:55,110 --> 00:11:58,650
+بالضبط، تقريرات أخرى أو تقرير آخر في الاقتصاد
+
+148
+00:11:58,650 --> 00:12:03,210
+أعتقد أن جزءًا من هذه التقريرات تم التحدث عنها في
+
+149
+00:12:03,210 --> 00:12:07,970
+الحلقة الأولى، الانفلاش، كما تعلمين أن الانفلاش هو
+
+150
+00:12:07,970 --> 00:12:09,750
+زيادة يزال يزال يزال يزال يزال يزال يزال يزال 
+
+151
+00:12:09,750 --> 00:12:10,170
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+152
+00:12:10,170 --> 00:12:11,150
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+153
+00:12:11,150 --> 00:12:11,810
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+154
+00:12:11,810 --> 00:12:12,190
+يزال يزال يزال يزال يزال يزال يزال يزال يزال يزال
+
+155
+00:12:12,190 --> 00:12:13,170
+يزال
+
+156
+00:12:23,940 --> 00:12:28,460
+لكن الانفلاتية هي زيادة في أعلى مستوى السعر 
+
+157
+00:12:28,460 --> 00:12:32,640
+لكل السلع والخدمات في الاقتصاد، في هذه الحالة
+
+158
+00:12:32,640 --> 00:12:39,280
+نستطيع أن نقول أننا لدينا ظاهرة انفلاتية، صح؟
+
+159
+00:12:39,280 --> 00:12:44,240
+ماذا عن الانفلات؟ الانفلاتية هي زيادة في
+
+160
+00:12:44,240 --> 00:12:49,920
+أعلى مستوى السعر في الاقتصاد، واختصارًا هي انفلاتية
+
+161
+00:12:49,920 --> 00:12:50,460
+مستمرة
+
+162
+00:12:53,280 --> 00:12:59,920
+التي هي الانفلاش الذي يستمر خلال فترة معينة، صح؟
+
+163
+00:12:59,920 --> 00:13:10,000
+أعتقد أنها ليست شيئًا جديدًا، لنذهب إلى أحد الموضوعات
+
+164
+00:13:10,000 --> 00:13:17,300
+المهمة في الاقتصاد، وهو قيمة المؤشرات، القيمة
+
+165
+00:13:17,300 --> 00:13:24,510
+المؤشرات هي أو تستخدم لتقيم مستويات القيمة من سنة
+
+166
+00:13:24,510 --> 00:13:28,550
+إلى سنة، أو عدد الاستخدام من سنة إلى سنة، لدينا 
+
+167
+00:13:28,550 --> 00:13:35,370
+ثلاثة مؤشرات أساسية، أسعار الأسعار الأولى هي GDP
+
+168
+00:13:35,370 --> 00:13:40,750
+Price Index أو GDP Deflator، والثاني هو Consumer
+
+169
+00:13:40,750 --> 00:13:46,430
+Price Index، والأخير هو Producer Price Index.
+
+170
+00:13:46,430 --> 00:13:52,230
+يعني الرقم القياسي للأسعار، كما تعلمين في
+
+171
+00:13:52,230 --> 00:13:55,970
+السلسلة الأخيرة، تحدثنا عن الـ GDP Deflator وكيف
+
+172
+00:13:55,970 --> 00:14:00,910
+يمكننا قياسها، أو كيف يمكننا قياس الـ GDP
+
+173
+00:14:00,910 --> 00:14:05,650
+Deflator، الـ GDP Deflator يقوم بقياس التغيير في
+
+174
+00:14:05,650 --> 00:14:09,990
+الأسعار، وعلى مستوى الأسعار من عام لعام باستخدام ما
+
+175
+00:14:09,990 --> 00:14:18,830
+يسمى سلة الأسعار، وهو يعتبر كل الأسعار في الاقتصاد
+
+176
+00:14:18,830 --> 00:14:26,510
+في الاقتصاد، ويعتبر كل الأسعار في الاقتصاد
+
+177
+00:14:26,510 --> 00:14:28,670
+ويعتبر كل الأسعار في الاقتصاد ويعتبر كل
+
+178
+00:14:28,670 --> 00:14:29,030
+الأسعار في الاقتصاد ويعتبر كل الأسعار
+
+179
+00:14:29,030 --> 00:14:33,990
+في الاقتصاد ويعتبر كل الأسعار في الاقتصاد
+
+180
+00:14:33,990 --> 00:14:35,470
+في الاقتصاد ويعتبر كل الأسعار في الاقتصاد
+
+181
+00:14:35,470 --> 00:14:35,750
+ويعتبر كل الأسعار في الاقتصاد ويعتبر كل
+
+182
+00:14:35,750 --> 00:14:35,830
+الاقتصاد ويعتبر كل الأسعار في الاقتصاد
+
+183
+00:14:35,830 --> 00:14:40,810
+ويعتبر كل ماذا؟ لأجهزة مجتمعية، ولكن ماذا
+
+184
+00:14:40,810 --> 00:14:44,130
+بالنسبة لـ Consumer Price Index؟ الـ Consumer 
+
+185
+00:14:44,130 --> 00:14:49,710
+Price Index مرتبط بالأجهزة التي يمتلكها المجتمع
+
+186
+00:14:49,710 --> 00:14:56,510
+فهي تقوم بقياس أسعار أو التغيير في مستوى السعر
+
+187
+00:14:56,510 --> 00:15:00,690
+العام للأجهزة التي يمتلكها أو الأجهزة التي يمتلكها
+
+188
+00:15:02,880 --> 00:15:07,020
+وهي تأخذ الكثير من المجموعات أو المجموعات المختلفة
+
+189
+00:15:07,020 --> 00:15:09,700
+من الأسعار والسلع، ويقوم بمقارنة أسعارها، لذا
+
+190
+00:15:09,700 --> 00:15:15,560
+فإن ... لكي
+
+191
+00:15:15,560 --> 00:15:17,380
+تفهم مصطلح أسعار الأسعار
+
+192
+00:15:20,990 --> 00:15:26,530
+مثلًا، أو الاقتصاديون كما ذكرت، الاقتصاديون استخدموا
+
+193
+00:15:26,530 --> 00:15:31,790
+قيم الأشياء التي اشتريتها أو الأشياء والسلوكيات
+
+194
+00:15:31,790 --> 00:15:35,990
+مهما كانت، مصدرها في المنطقة أو اشتريتها من خارج
+
+195
+00:15:35,990 --> 00:15:42,330
+البلد، صح؟ وهم يأخذون مجموعات مختلفة من الأشياء،
+
+196
+00:15:42,330 --> 00:15:45,670
+فمثلًا يأخذون الطعام،
+
+197
+00:15:50,820 --> 00:15:53,060
+التواصل التواصل التواصل التواصل التواصل التواصل
+
+198
+00:15:53,060 --> 00:15:56,340
+التواصل التواصل التواصل التواصل التواصل التواصل
+
+199
+00:15:56,340 --> 00:15:57,800
+التواصل التواصل التواصل التواصل التواصل التواصل
+
+200
+00:15:57,800 --> 00:16:03,620
+التواصل التواصل التواصل
+
+201
+00:16:03,620 --> 00:16:08,240
+التواصل التواصل التواصل التواصل التواصل التواصل
+
+202
+00:16:08,240 --> 00:16:09,960
+التواصل التواصل التواصل التواصل التواصل التواصل
+
+203
+00:16:09,960 --> 00:16:13,030
+التواصل التواصل التواصل التواصل التواصل، وذلك يقومون
+
+204
+00:16:13,030 --> 00:16:16,590
+بمعاملة أسعار أو يقومون بمعاملة أسعار من هذه
+
+205
+00:16:16,590 --> 00:16:21,590
+المجموعات من الأسعار خلال السنوات، ولكنها لديها
+
+206
+00:16:21,590 --> 00:16:31,610
+مشكلتين، وهذه المشكلتين هما أنها لا تعتبر 
+
+207
+00:16:31,610 --> 00:16:37,840
+كل الأسعار والخدمات في الاقتصاد، they focus on what?
+
+208
+00:16:38,360 --> 00:16:44,140
+only yes exactly a bundle of goods and they focus
+
+209
+00:16:44,140 --> 00:16:51,430
+on only the purchased products أو ... نعم، هم
+
+210
+00:16:51,430 --> 00:16:55,550
+يشتغلون على المواصفات، لذا فإنهم غيروا المواصفات
+
+211
+00:16:55,550 --> 00:17:02,030
+أو المواصفات أو قيم الأجهزة أو القيم ... لذا فإنهم 
+
+212
+00:17:02,030 --> 00:17:06,510
+يركزون على المواصفات والمواصفات والمواصفات
+
+213
+00:17:06,510 --> 00:17:07,410
+والمواصفات والمواصفات والمواصفات والمواصفات
+
+214
+00:17:07,410 --> 00:17:07,610
+والمواصفات والمواصفات والمواصفات والمواصفات
+
+215
+00:17:07,610 --> 00:17:07,650
+والمواصفات والمواصفات والمواصفات والمواصفات
+
+216
+00:17:07,650 --> 00:17:16,950
+والمواصفات والمواصفات والمواصفات والمواصف
+
+217
+00:17:17,560 --> 00:17:22,980
+في بعض الأحيان، إذا أخذوا خمس مرات من الملابس
+
+218
+00:17:22,980 --> 00:17:28,060
+وقاموا بقياس الأسعار أو التغيير في الأسعار خلال
+
+219
+00:17:28,060 --> 00:17:35,440
+السنوات، فإن جزءًا من هذه المرات من الملابس قد يكون
+
+220
+00:17:35,440 --> 00:17:43,960
+خارجيًا، أو فإننا نتحدث عن التلفاز، نعم، أنت تعرف
+
+221
+00:17:45,870 --> 00:17:50,730
+وTVs بلد بلد بلد بلد
+
+222
+00:17:50,730 --> 00:17:51,590
+بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد
+
+223
+00:17:51,590 --> 00:17:53,550
+بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد
+
+224
+00:17:53,550 --> 00:17:53,570
+بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد
+
+225
+00:17:53,570 --> 00:17:53,610
+بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد بلد
+
+226
+00:17:53,610 --> 00:17:56,310
+بلد بلد بلد بلد بلد بلد بلد بلد بلد
+
+227
+00:18:05,940 --> 00:18:11,400
+ولكن الآن لديها تغيير، لا أحد يستخدم تلفزيون أسود
+
+228
+00:18:11,400 --> 00:18:20,240
+وأسود، ولكن باعتبار قيمة المستخدم، ستكون متوفرة
+
+229
+00:18:20,240 --> 00:18:28,490
+لتقيم قيمة مجموعات مختلفة من الخيارات، عمليًا الأسعار
+
+230
+00:18:28,490 --> 00:18:32,130
+بيخلوها، يعني هي سلع قديمة تستخدم لكن بتضلها في
+
+231
+00:18:32,130 --> 00:18:34,970
+القياسات عندهم في قياسات ال consumer price index
+
+232
+00:18:38,120 --> 00:18:45,940
+لنذهب إلى المصطلحات والمعلومات عن قيمة المخزن كما
+
+233
+00:18:45,940 --> 00:18:51,960
+ترى، أو قيمة المخزن هم استخدامها لتقوم بمعاملة قيمة
+
+234
+00:18:51,960 --> 00:18:56,580
+المخزن بشكل عام، قيمة المخزن التي تتعلق بكل الأسواق
+
+235
+00:18:56,580 --> 00:19:03,770
+والخدمات في الاقتصاد هي قيمة GDP، قيمة القيمة GDP
+
+236
+00:19:03,770 --> 00:19:11,030
+تقيم قيمة جميع الأجهزة التي تنتجها في الاقتصاد
+
+237
+00:19:11,030 --> 00:19:16,290
+دعونا نذهب إلى قيمة الشركات، كما ترى CPI هي قيمة
+
+238
+00:19:16,290 --> 00:19:24,150
+الشركات، هي قيمة تقيمتها كل أسبوع بمجموعة
+
+239
+00:19:24,150 --> 00:19:32,510
+مجتمع مجتمع مجتمع مجتمع مجتمع مجتمع مجتمع سلة ...
+
+240
+00:19:32,510 --> 00:19:35,990
+سلة المستهلك أو سلة اللي هي ال different bundles
+
+241
+00:19:35,990 --> 00:19:41,880
+تمام؟ وقت ياس purchased monthly, so here we're
+
+242
+00:19:41,880 --> 00:19:45,760
+talking about the purchased products, whether it
+
+243
+00:19:45,760 --> 00:19:50,980
+was either it was purchased from inside or outside
+
+244
+00:19:50,980 --> 00:19:55,620
+the country, حزم ثابت و بطبقها على لسنين كلها، there
+
+245
+00:19:55,620 --> 00:19:59,260
+is no change in the different types، يمكن بعد after
+
+246
+00:19:59,260 --> 00:20:03,440
+10 years, after 20 years، بيغيروا اللي هو ال ... ال
+
+247
+00:20:03,440 --> 00:20:03,820
+... ال ... ال ... ال ... ال ... ال ... ال ... ال ... ال ...
+
+248
+00:20:03,820 --> 00:20:04,060
+ال ... ال ... ال ... ال ... ال ... ال ... ال ... ال ... ال
+
+249
+00:20:04,060 --> 00:20:04,500
+... ال ... ال ... ال ... ال ... ال ... ال ... ال ... ال ...
+
+250
+00:20:04,500 --> 00:20:04,700
+ال ... ال ... ال ... ال ... ال ... ال ... ال ... ال ... ال
+
+251
+00:20:04,700 --> 00:20:05,060
+... ال ... ال ... ال ... ال ... ال ... ال ... ال ... ال ...
+
+252
+00:20:05,060 --> 00:20:06,000
+ال ... ال ... ال ... ال ... ال ... ال ... ال ... ال ... ال
+
+253
+00:20:06,000 --> 00:20:08,720
+... ال ... ال ... ال ... ال ... ال ... ال ... ال ... لذلك،
+
+254
+00:20:08,720 --> 00:20:14,280
+كما تشاهد، قيمة المستخدم، Index، Market Basket،
+
+255
+00:20:14,280 --> 00:20:17,940
+تظهر كيف يقوم مستخدم طبيعي بشراء دولته أو دولته
+
+256
+00:20:17,940 --> 00:20:22,900
+من بين العديد من السلع والخدمات. كما تشاهد، هذا
+
+257
+00:20:22,900 --> 00:20:28,540
+الـ دياغرام يظهر شراء
+
+258
+00:20:28,540 --> 00:20:38,750
+من مستخدم طبيعي، كما تشاهد، يقضي 4.3 على 5.8 على
+
+259
+00:20:38,750 --> 00:20:42,190
+التعليم والتواصل، كما تشاهد، التجارة، التعليم
+
+260
+00:20:42,190 --> 00:20:43,070
+والتعليم والتعليم والتعليم والتعليم والتعليم
+
+261
+00:20:43,070 --> 00:20:43,110
+والتعليم والتعليم والتعليم والتعليم والتعليم
+
+262
+00:20:43,110 --> 00:20:44,470
+والتعليم والتعليم والتعليم والتعليم والتعليم
+
+263
+00:20:44,470 --> 00:20:45,330
+والتعليم والتعليم والتعليم والتعليم والتعليم
+
+264
+00:20:45,330 --> 00:20:45,470
+والتعليم والتعليم والتعليم والتعليم والتعليم
+
+265
+00:20:45,470 --> 00:20:55,650
+والتعليم والتعليم والتعليم والتعليم والتعليم
+
+266
+00:20:55,650 --> 00:20:58,070
+والتعلي
+
+267
+00:20:59,060 --> 00:21:02,720
+measures the price change for the products at all
+
+268
+00:21:02,720 --> 00:21:06,560
+stages، اللي هم إيش؟ and the production prices، the
+
+269
+00:21:06,560 --> 00:21:09,780
+three main categories are the finished goods,
+
+270
+00:21:10,540 --> 00:21:15,420
+intermediate material and crude material، مواد
+
+271
+00:21:15,420 --> 00:21:21,160
+الخام، بيجي بيعمل تسعيرة لأسعار ال finished goods
+
+272
+00:21:21,620 --> 00:21:25,840
+الـ intermediate material and the crude material
+
+273
+00:21:25,840 --> 00:21:29,040
+in each year and do a comparison, and then they can
+
+274
+00:21:29,040 --> 00:21:32,220
+do a comparison between the prices that changes in
+
+275
+00:21:32,220 --> 00:21:35,680
+the overall price levels for or at each stage
+
+276
+00:21:35,680 --> 00:21:42,800
+right, okay, what about the costs of inflation or
+
+277
+00:21:42,800 --> 00:21:46,360
+the consequences, the bad consequences or the
+
+278
+00:21:46,360 --> 00:21:51,180
+negative consequences of inflation، مفهوم أن تفهم
+
+279
+00:21:51,180 --> 00:21:57,680
+تأثيرات مفاوضة و افعاليات الانفلاش، مفهوم أنك تحصل
+
+280
+00:21:57,680 --> 00:22:01,620
+على مبلغ 
+
+281
+00:22:01,620 --> 00:22:08,440
+أساسي من ألف دولار أساسي من ألف دولار أساسي من ألف
+
+282
+00:22:08,440 --> 00:22:10,400
+دولار أساسي من ألف دولار أساسي من ألف دولار أساسي
+
+283
+00:22:10,400 --> 00:22:13,280
+من ألف دولار أساسي من ألف دولار أساسي من ألف دولار
+
+284
+00:22:13,280 --> 00:22:17,540
+أساسي من ألف دولار أساسي من ألف دولار أساسي من ألف
+
+285
+00:22:17,540 --> 00:22:17,560
+من ألف دولار أساسي من ألف دولار أساسي من ألف دولار
+
+286
+00:22:17,560 --> 00:22:21,570
+أساسي من ألف دولار أساسي من ألف دولار إذا حصلت على
+
+287
+00:22:21,570 --> 00:22:26,530
+نفس الأموال أو أموال المحفظة في هذه الحالة فإن قوة
+
+288
+00:22:26,530 --> 00:22:30,910
+الحصول أو قوة حصولك ستتخلص تمامًا، ستتخلص
+
+289
+00:22:30,910 --> 00:22:37,830
+تمامًا، لذلك ستتآكل، صح؟ حتى تتآكل، إذا من يتآكل
+
+290
+00:22:37,830 --> 00:22:43,430
+من التضخم؟ اللي .. نعم، المعمل اللي يحصل ..
+
+291
+00:22:43,430 --> 00:22:49,800
+ماذا؟ أموال المحفظة تمام؟ واحد بياخد دخل ثابت يبقى
+
+292
+00:22:49,800 --> 00:22:52,980
+معنى أن الـ .. الـ .. الـ .. الرواتب تبعه مش مربوط 
+
+293
+00:22:52,980 --> 00:22:57,680
+بجدول غلاء المعيشة فهذا بيتضرر، so in this case
+
+294
+00:22:57,680 --> 00:23:00,460
+the nominal .. if the nominal income هذا ال
+
+295
+00:23:00,460 --> 00:23:02,820
+nominal .. this is the nominal income الدخل اللي
+
+296
+00:23:02,820 --> 00:23:07,180
+اسمه، but if the price is increased the real income
+
+297
+00:23:07,180 --> 00:23:11,260
+would what؟ would decline, right؟ so if he received
+
+298
+00:23:11,260 --> 00:23:13,620
+a one thousand .. receives a one thousand dollar
+
+299
+00:23:13,620 --> 00:23:14,780
+as a nominal income
+
+300
+00:23:19,340 --> 00:23:24,320
+إذا ارتفاع الأسعار أو ارتفاع الأسعار يتسبب في
+
+301
+00:23:24,320 --> 00:23:31,840
+ماذا؟ في تنقل قوة الحصول على هذا الموظف والأسعار
+
+302
+00:23:31,840 --> 00:23:38,740
+الحقيقية مع ما يتسبب في تنقل الأسعار الحقيقية ماذا
+
+303
+00:23:38,740 --> 00:23:45,920
+آخر؟ من سيحرر من الـ .. ومن سيستفيد من التضخم؟
+
+304
+00:23:48,970 --> 00:23:55,550
+المصادر .. حسنًا سوف نتكلم عن هذا الموضوع ولكن أود
+
+305
+00:23:55,550 --> 00:24:02,310
+أن أتحدث عن المستخدمين والمستخدمين إذا اليوم أعطي
+
+306
+00:24:02,310 --> 00:24:10,530
+أو أعطي أو أعطي إذا 
+
+307
+00:24:10,530 --> 00:24:24,760
+اليوم أعطي أناس 1000 شيكل اليوم أعطيت أناس 1000 شيكل
+
+308
+00:24:24,760 --> 00:24:32,020
+اليوم اليوم أنا
+
+309
+00:24:32,020 --> 00:24:36,780
+المستخدم اليوم 
+
+310
+00:24:36,780 --> 00:24:44,140
+1000 دولار أو 1000 شيكل يستطيع أن يشتري 
+
+311
+00:24:48,470 --> 00:24:53,750
+الكيس الطحين كده حجوها؟ okay one hundred شيكل okay
+
+312
+00:24:53,750 --> 00:24:58,370
+so in this case I can buy suppose that the price
+
+313
+00:24:58,370 --> 00:25:06,410
+per sack of flour the price per sack of a 
+
+314
+00:25:06,410 --> 00:25:17,510
+flour is one hundred شيكل in this case أنا أستطيع
+
+315
+00:25:17,510 --> 00:25:21,670
+أن أشتري 10 سـ
+
+316
+00:25:21,670 --> 00:25:33,090
+ساكات من الطحين بعد التضخم، إذا أعطيته لمدة 2
+
+317
+00:25:33,090 --> 00:25:37,950
+عامين للمقابل 2 عامين كما تعلمين بشكل عام السعر
+
+318
+00:25:37,950 --> 00:25:47,710
+أكثر بشكل عام السعر أكثر بشكل عام بعد عامين أو
+
+319
+00:25:47,710 --> 00:25:49,090
+عامين أو عامين أو عامين أو عامين أو عامين أو عامين
+
+320
+00:25:49,090 --> 00:25:52,610
+أو عامين أو عامين أو عامين أو عامين أو
+
+321
+00:25:52,610 --> 00:25:53,690
+عامين أو عامين أو عامين أو عامين أو عامين أو عامين
+
+322
+00:25:53,690 --> 00:25:55,090
+أو عامين أو عامين أو عامين أو عامين أو عامين أو
+
+323
+00:25:55,090 --> 00:25:55,630
+عامين أو عامين أو عامين أو عامين أو عامين أو عامين
+
+324
+00:25:55,630 --> 00:26:00,150
+أو عامين أو عامين أو عامين أو عامين أو عامين أو
+
+325
+00:26:00,150 --> 00:26:04,050
+أو عامين أو عامين
+
+326
+00:26:04,050 --> 00:26:08,590
+أو عامين أو عامين أو عامين أو عام
+
+327
+00:26:12,330 --> 00:26:18,530
+ولكن السعر هو 150
+
+328
+00:26:18,530 --> 00:26:24,570
+شيكل إذا
+
+329
+00:26:24,570 --> 00:26:33,750
+كنت ترى السعر ازداد ازداد ازداد ازداد ازداد
+
+330
+00:26:33,750 --> 00:26:38,570
+ازداد ازداد ازداد ازداد ازداد ازداد ازداد ازداد ازداد ازداد
+
+331
+00:26:38,570 --> 00:26:39,170
+ازداد
+
+332
+00:26:41,890 --> 00:26:47,110
+هذا يسبب في أقل قوة الحصول على المال في هذه الحالة
+
+333
+00:26:47,110 --> 00:26:58,430
+أستطيع أن أحصل على كم؟ 1000 شيكل على 150 يعني كم؟ 6
+
+334
+00:26:58,430 --> 00:27:07,410
+.6 5.2 في هذه الحالة الشخص الذي يحصل على المال أو
+
+335
+00:27:07,410 --> 00:27:07,870
+المستخدم
+
+336
+00:27:10,970 --> 00:27:17,990
+ماله؟ خسر، صح؟ بس مين المستفيد؟ who benefits؟ the
+
+337
+00:27:17,990 --> 00:27:19,070
+borrower
+
+338
+00:27:27,740 --> 00:27:53,240
+تمام تمام تمام
+
+339
+00:27:53,240 --> 00:27:57,400
+تمام تمام تمام تمام
+
+340
+00:27:57,400 --> 00:27:57,420
+تمام تمام تمام تمام تمام تمام تمام تمام تمام تمام
+
+341
+00:27:57,420 --> 00:28:12,240
+تمام تمام تمام تمام القيمة الحقيقية أعتقد
+
+342
+00:28:12,240 --> 00:28:24,360
+أنك لديك 1000$ 1000$ وأنت
+
+343
+00:28:25,450 --> 00:28:29,310
+deposit or decided to put it in the bank to
+
+344
+00:28:29,310 --> 00:28:41,110
+deposit it in the bank with 
+
+345
+00:28:41,110 --> 00:28:46,730
+an interest rate of seven seven percent البنك جالك بده
+
+346
+00:28:46,730 --> 00:28:52,470
+يعطيك فائدة قد إيش seven seven percent as interest
+
+347
+00:28:52,470 --> 00:29:07,660
+rate for a one year في عام واحد في عام واحد
+
+348
+00:29:07,660 --> 00:29:17,000
+في عام واحد في عام واحد في عام واحد في عام واحد في
+
+349
+00:29:17,000 --> 00:29:20,780
+عام
+
+350
+00:29:20,780 --> 00:29:27,460
+واحد Okay one thousand مظبوط مظبوط right this is
+
+351
+00:29:27,460 --> 00:29:35,060
+what this is the nominal interest rate, right
+
+352
+00:29:35,060 --> 00:29:39,660
+suppose during this year the inflation or the
+
+353
+00:29:39,660 --> 00:29:47,120
+price is increased by the same by the same
+
+354
+00:29:47,120 --> 00:29:48,200
+percentage
+
+355
+00:29:55,640 --> 00:30:01,660
+ماذا استفدنا؟ لا شيء، صح؟ لأن الفرق بين ..
+
+356
+00:30:01,660 --> 00:30:07,080
+الواقعي .. الواقعي الفائدة الفائدة الفائدة
+
+357
+00:30:07,080 --> 00:30:09,120
+الفائدة الفائدة
+
+358
+00:30:11,730 --> 00:30:15,330
+القيمة الفعلية هي القيمة الفعلية الفعلية الفعلية
+
+359
+00:30:15,330 --> 00:30:16,230
+الفعليّة الفعليّة الفعليّة الفعليّة الفعليّة
+
+360
+00:30:16,230 --> 00:30:18,790
+الفعليّة الفعليّة الفعليّة الفعليّة الفعليّة
+
+361
+00:30:18,790 --> 00:30:20,610
+الفعليّة الفعليّة الفعليّة الفعليّة الفعليّة
+
+362
+00:30:20,610 --> 00:30:21,590
+الفعليّة الفعليّة الفعليّة الفعليّة الفعليّة
+
+363
+00:30:21,590 --> 00:30:26,990
+الفعليّة الفعليّة الفعليّة الفعليّة الفعليّة
+
+364
+00:30:26,990 --> 00:30:27,450
+الفعليّة الفعليّة الفعليّة الفعليّة الفعليّة
+
+365
+00:30:27,450 --> 00:30:27,470
+الفعليّة الفعليّة الفعليّة الفعليّة الفعليّة
+
+366
+00:30:27,470 --> 00:30:36,830
+الفعليّة الفعليّة الفعليّة الفعليّة الفع
+
+367
+00:30:37,580 --> 00:30:42,280
+جميع الافتراضات الأخرى مرتبطة أو مهتمة Ceteris paribus نحن
+
+368
+00:30:42,280 --> 00:30:46,900
+الآن نتكلم عن معدل الاستثمار أو السعر المزيد من 7%
+
+369
+00:30:46,900 --> 00:30:53,100
+معدل الاستثمار المعين هو 7% لذلك مع اهتمامك أو معدل
+
+370
+00:30:53,100 --> 00:30:56,780
+الاستثمار الحقيقي سيكون 0، لكن إذا معدل الاستثمار أو
+
+371
+00:30:56,780 --> 00:31:01,780
+الاستثمار ازداد 5% كم هو معدل الاستثمار الحقيقي
+
+372
+00:31:01,780 --> 00:31:13,890
+الذي تحصل عليه من البنك 7%-5% ينخفض لـ 2% صح؟
+
+373
+00:31:13,890 --> 00:31:19,990
+طيب Suppose the bank decided to give you 7% and the
+
+374
+00:31:19,990 --> 00:31:24,090
+inflation rate is 10% during this year there is a
+
+375
+00:31:24,090 --> 00:31:28,770
+loss by three percent صح احنا بنحكي we are talking
+
+376
+00:31:28,770 --> 00:31:31,830
+about Ceteris paribus purpose means أن كل العوامل الأخرى
+
+377
+00:31:31,830 --> 00:31:35,270
+ثابتة على حالها we are talking about the value of
+
+378
+00:31:35,270 --> 00:31:38,730
+currencies is constant and we have an interest rate
+
+379
+00:31:38,730 --> 00:31:41,110
+by seven percent
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/YZ7hqRoNrAE_raw.json b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/YZ7hqRoNrAE_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..3b2829c574cff5a086433c1775cf0164b9243544
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/YZ7hqRoNrAE_raw.json
@@ -0,0 +1 @@
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{"start": 368.43, "end": 369.17, "word": " قررت", "probability": 0.76483154296875}, {"start": 369.17, "end": 369.91, "word": " تقليل", "probability": 0.53497314453125}, {"start": 369.91, "end": 370.55, "word": " المجالات", "probability": 0.452423095703125}, {"start": 370.55, "end": 371.43, "word": " او", "probability": 0.6734619140625}, {"start": 371.43, "end": 371.69, "word": " المجالات", "probability": 0.84014892578125}, {"start": 371.69, "end": 372.27, "word": " الاجتماعية", "probability": 0.7065633138020834}, {"start": 372.27, "end": 373.33, "word": " على", "probability": 0.27783203125}, {"start": 373.33, "end": 374.85, "word": " 100", "probability": 0.66015625}, {"start": 374.85, "end": 375.83, "word": " مليون", "probability": 0.986328125}, {"start": 375.83, "end": 376.19, "word": " دولار", "probability": 0.9905598958333334}, {"start": 376.19, "end": 376.43, "word": " لذا", "probability": 0.4522705078125}, {"start": 376.43, "end": 376.81, "word": " لدينا", "probability": 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"word": " النسبة", "probability": 0.7488606770833334}, {"start": 401.96, "end": 402.46, "word": " العامة", "probability": 0.9876302083333334}, {"start": 402.46, "end": 403.36, "word": " لأن", "probability": 0.830078125}, {"start": 403.36, "end": 404.42, "word": " تقليل", "probability": 0.7156982421875}, {"start": 404.42, "end": 404.78, "word": " الوضع", "probability": 0.47943115234375}, {"start": 404.78, "end": 406.1, "word": " يؤدي", "probability": 0.6731770833333334}, {"start": 406.1, "end": 406.34, "word": " إلى", "probability": 0.7900390625}, {"start": 406.34, "end": 407.16, "word": " تصميم", "probability": 0.5518341064453125}, {"start": 407.16, "end": 407.38, "word": " النسبة", "probability": 0.6740315755208334}, {"start": 407.38, "end": 407.92, "word": " العامة", "probability": 0.9928385416666666}], "temperature": 1.0}, {"id": 18, "seek": 42057, "start": 409.35, "end": 420.57, "text": "أو تحرير الانتجار بإزالة نتيجة الانتجار، لذلك كما ترى Delta Y أو Delta T اقل من MBC", "tokens": 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"text": "طيب what about the effect of taxes on aggregate output؟ this is the question", "tokens": [9566, 1829, 3555, 437, 466, 264, 1802, 295, 10041, 322, 26118, 5598, 22807, 341, 307, 264, 1168], "avg_logprob": -0.5399305356873406, "compression_ratio": 1.0, "no_speech_prob": 9.5367431640625e-07, "words": [{"start": 1409.69, "end": 1410.03, "word": "طيب", "probability": 0.6700032552083334}, {"start": 1410.03, "end": 1410.47, "word": " what", "probability": 0.1649169921875}, {"start": 1410.47, "end": 1410.79, "word": " about", "probability": 0.93994140625}, {"start": 1410.79, "end": 1410.99, "word": " the", "probability": 0.76953125}, {"start": 1410.99, "end": 1411.29, "word": " effect", "probability": 0.74853515625}, {"start": 1411.29, "end": 1411.47, "word": " of", "probability": 0.958984375}, {"start": 1411.47, "end": 1411.89, "word": " taxes", "probability": 0.9287109375}, {"start": 1411.89, "end": 1412.19, "word": " on", "probability": 0.92919921875}, {"start": 1412.19, "end": 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This means what? 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"probability": 0.83056640625}, {"start": 2547.09, "end": 2547.43, "word": " بسبب", "probability": 0.84130859375}, {"start": 2547.43, "end": 2547.95, "word": " التغيير", "probability": 0.83526611328125}, {"start": 2547.95, "end": 2548.11, "word": " في", "probability": 0.93505859375}, {"start": 2548.11, "end": 2548.13, "word": " الـ", "probability": 0.173248291015625}, {"start": 2548.13, "end": 2548.35, "word": " Government", "probability": 0.417724609375}, {"start": 2548.35, "end": 2548.83, "word": " Spending", "probability": 0.86083984375}, {"start": 2548.83, "end": 2549.55, "word": " ومن", "probability": 0.4261474609375}, {"start": 2549.55, "end": 2549.55, "word": " ثم", "probability": 0.929443359375}, {"start": 2549.55, "end": 2549.89, "word": " في", "probability": 0.109619140625}, {"start": 2549.89, "end": 2550.25, "word": " المجالات", "probability": 0.491729736328125}, {"start": 2550.25, "end": 2551.73, "word": " ومن", "probability": 0.533935546875}, {"start": 2551.73, "end": 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"probability": 0.94189453125}], "temperature": 1.0}, {"id": 106, "seek": 259023, "start": 2588.68, "end": 2590.24, "text": "عالقالة سريعة عن هيك شباب", "tokens": [3615, 6027, 4587, 6027, 3660, 8608, 16572, 27884, 18871, 39896, 4117, 13412, 3555, 16758], "avg_logprob": -0.5317708492279053, "compression_ratio": 0.8846153846153846, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 2588.6800000000003, "end": 2589.28, "word": "عالقالة", "probability": 0.493798828125}, {"start": 2589.28, "end": 2589.58, "word": " سريعة", "probability": 0.8312174479166666}, {"start": 2589.58, "end": 2589.72, "word": " عن", "probability": 0.6162109375}, {"start": 2589.72, "end": 2589.9, "word": " هيك", "probability": 0.801513671875}, {"start": 2589.9, "end": 2590.24, "word": " شباب", "probability": 0.8430989583333334}], "temperature": 1.0}, {"id": 107, "seek": 262804, "start": 2598.8, "end": 2628.04, "text": "هذا هو ماذا؟ التغيير في الوصول المجتمعي بسبب التغيير في المجتمع المجتمعي بسبب التغيير في 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"end": 2678.27, "word": " او", "probability": 0.95556640625}, {"start": 2678.27, "end": 2678.61, "word": " 200", "probability": 0.92724609375}, {"start": 2678.61, "end": 2678.61, "word": " مليون", "probability": 0.99169921875}, {"start": 2678.61, "end": 2678.61, "word": " دولار", "probability": 0.9964192708333334}, {"start": 2678.61, "end": 2679.07, "word": " او", "probability": 0.954345703125}, {"start": 2679.07, "end": 2679.17, "word": " 200", "probability": 0.92724609375}, {"start": 2679.17, "end": 2679.25, "word": " مليون", "probability": 0.9915364583333334}, {"start": 2679.25, "end": 2679.29, "word": " دولار", "probability": 0.99658203125}, {"start": 2679.29, "end": 2679.37, "word": " او", "probability": 0.952392578125}, {"start": 2679.37, "end": 2679.37, "word": " 200", "probability": 0.92529296875}, {"start": 2679.37, "end": 2679.37, "word": " مليون", "probability": 0.9913736979166666}, {"start": 2679.37, "end": 2679.37, "word": " دولار", "probability": 0.9967447916666666}, {"start": 2679.37, "end": 2680.77, "word": " او", "probability": 0.95166015625}, {"start": 2680.77, "end": 2681.45, "word": " 200", "probability": 0.9248046875}, {"start": 2681.45, "end": 2681.45, "word": " مليون", "probability": 0.9912109375}, {"start": 2681.45, "end": 2681.97, "word": " دولار", "probability": 0.9969075520833334}, {"start": 2681.97, "end": 2682.11, "word": " او", "probability": 0.955322265625}, {"start": 2682.11, "end": 2682.31, "word": " 200", "probability": 0.9228515625}, {"start": 2682.31, "end": 2682.31, "word": " م", "probability": 0.9814453125}], "temperature": 1.0}, {"id": 110, "seek": 270823, "start": 2706.83, "end": 2708.23, "text": "YGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYT", "tokens": [56, 38, 56, 51, 56, 38, 56, 51, 56, 38, 56, 51, 56, 38, 56, 51, 56, 38, 56, 51, 56, 38, 56, 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"YGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYTYGYT", "probability": 0.9581068583897182}], "temperature": 1.0}, {"id": 111, "seek": 273141, "start": 2708.67, "end": 2731.41, "text": "كما ذكرنا، الانقلاب الجديد هنا أو الانقلاب القديم كان في 500، بالضبط، الآن يجب أن نضيف 533، لذلك يجب أن يكون هنا 1033، هذا هو الانقلاب الجديد", "tokens": [4117, 15042, 29910, 37983, 8315, 12399, 2423, 7649, 4587, 15040, 3555, 25724, 16254, 3215, 34105, 34051, 2423, 7649, 4587, 15040, 3555, 25062, 16254, 2304, 25961, 8978, 5923, 12399, 20666, 11242, 3555, 9566, 12399, 6024, 48506, 7251, 7435, 3555, 14739, 8717, 11242, 33911, 1025, 10191, 12399, 5296, 8848, 23275, 7251, 7435, 3555, 14739, 7251, 30544, 34105, 1266, 10191, 12399, 23758, 31439, 2423, 7649, 4587, 15040, 3555, 25724, 16254, 3215], "avg_logprob": -0.39447463940883026, 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"probability": 0.37359619140625}, {"start": 2716.51, "end": 2717.59, "word": " بالضبط،", "probability": 0.7638671875}, {"start": 2717.59, "end": 2717.99, "word": " الآن", "probability": 0.57421875}, {"start": 2717.99, "end": 2718.47, "word": " يجب", "probability": 0.8229166666666666}, {"start": 2718.47, "end": 2718.61, "word": " أن", "probability": 0.73095703125}, {"start": 2718.61, "end": 2719.01, "word": " نضيف", "probability": 0.9197591145833334}, {"start": 2719.01, "end": 2722.09, "word": " 533،", "probability": 0.8019205729166666}, {"start": 2722.09, "end": 2722.93, "word": " لذلك", "probability": 0.6133626302083334}, {"start": 2722.93, "end": 2724.17, "word": " يجب", "probability": 0.9098307291666666}, {"start": 2724.17, "end": 2724.25, "word": " أن", "probability": 0.91552734375}, {"start": 2724.25, "end": 2724.33, "word": " يكون", "probability": 0.952392578125}, {"start": 2724.33, "end": 2724.67, "word": " هنا", "probability": 0.91796875}, {"start": 2724.67, "end": 2729.09, "word": " 1033،", "probability": 0.705810546875}, {"start": 2729.09, "end": 2730.55, "word": " هذا", "probability": 0.6591796875}, {"start": 2730.55, "end": 2730.71, "word": " هو", "probability": 0.53173828125}, {"start": 2730.71, "end": 2731.41, "word": " الانقلاب", "probability": 0.882470703125}, {"start": 2731.41, "end": 2731.41, "word": " الجديد", "probability": 0.9900716145833334}], "temperature": 1.0}, {"id": 112, "seek": 274783, "start": 2736.75, "end": 2747.83, "text": "this is the aggregate expenditure ده new equilibrium point صح؟ مصبوط؟ صعب الأمور ولا .. يعطيكم العافية", "tokens": [11176, 307, 264, 26118, 40377, 11778, 3224, 777, 15625, 935, 20328, 5016, 22807, 3714, 9381, 3555, 2407, 9566, 22807, 20328, 3615, 3555, 16247, 2304, 13063, 49429, 4386, 37495, 9566, 1829, 24793, 18863, 31845, 10632], "avg_logprob": -0.33214285543986727, "compression_ratio": 1.078125, "no_speech_prob": 0.0, "words": [{"start": 2736.75, "end": 2737.01, "word": "this", "probability": 0.28759765625}, {"start": 2737.01, "end": 2737.19, "word": " is", "probability": 0.96337890625}, {"start": 2737.19, "end": 2737.35, "word": " the", "probability": 0.38134765625}, {"start": 2737.35, "end": 2737.75, "word": " aggregate", "probability": 0.9208984375}, {"start": 2737.75, "end": 2738.59, "word": " expenditure", "probability": 0.96142578125}, {"start": 2738.59, "end": 2739.17, "word": " ده", "probability": 0.5889892578125}, {"start": 2739.17, "end": 2739.35, "word": " new", "probability": 0.365234375}, {"start": 2739.35, "end": 2739.81, "word": " equilibrium", "probability": 0.94287109375}, {"start": 2739.81, "end": 2740.39, "word": " point", "probability": 0.990234375}, {"start": 2740.39, "end": 2742.15, "word": " صح؟", "probability": 0.7626139322916666}, {"start": 2742.15, "end": 2744.79, "word": " مصبوط؟", "probability": 0.6632486979166666}, {"start": 2744.79, "end": 2745.05, "word": " صعب", "probability": 0.9847005208333334}, {"start": 2745.05, "end": 2745.35, "word": " الأمور", 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\ No newline at end of file
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/vO90yhNTu5s.srt b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/vO90yhNTu5s.srt
new file mode 100644
index 0000000000000000000000000000000000000000..449210329bc86dbda20a84db2b5a1802d11416ff
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/vO90yhNTu5s.srt
@@ -0,0 +1,2227 @@
+1
+00:00:21,210 --> 00:00:27,430
+بسم الله الرحمن الرحيم اليوم بإذن الله سنتحدث
+
+2
+00:00:27,430 --> 00:00:31,970
+عن قسم 9 سنقوم بعمل بعض التدريبات على هذا القسم
+
+3
+00:00:31,970 --> 00:00:38,970
+لذلك دعونا نبدأ مع هذه التدريبات أو الأسئلة كما 
+
+4
+00:00:38,970 --> 00:00:44,090
+ترى السؤال الأول هو في كل موقع من خلال خطوط
+
+5
+00:00:44,090 --> 00:00:47,760
+التطبيق التجاري يعتمد على مجتمع غير أسلوب ماذا هو
+
+6
+00:00:47,760 --> 00:00:52,120
+الإجابة الصحيحة؟ الإجابة الصحيحة هي Y يقل C plus I
+
+7
+00:00:52,120 --> 00:00:58,720
+plus G في المعادلة، صحيح؟ تقريبًا في المال أو 
+
+8
+00:00:58,720 --> 00:01:03,520
+المال المطلوب، تقريبًا في المال المطلوب، آسف،
+
+9
+00:01:03,520 --> 00:01:06,820
+مصادر المال، يؤدي إلى ماذا؟ تقريبًا مصادر المال 
+
+10
+00:01:08,270 --> 00:01:14,770
+استخدام R يقل I ويقل الأسعار المجاورة ويقل 
+
+11
+00:01:14,770 --> 00:01:17,710
+المطالبة المجاورة للمطالبة المجاورة للمطالبة 
+
+12
+00:01:17,710 --> 00:01:20,290
+المجاورة المجاورة المجاورة المجاورة المجاورة 
+
+13
+00:01:20,290 --> 00:01:25,790
+المجاورة المجاورة المجاورة المجاورة المجاورة
+
+14
+00:01:25,790 --> 00:01:25,850
+المجاورة المجاورة المجاورة المجاورة المجاورة
+
+15
+00:01:25,850 --> 00:01:25,930
+المجاورة المجاورة المجاورة المجاورة المجاورة
+
+16
+00:01:25,930 --> 00:01:29,570
+المجاورة المجاورة المجاورة
+
+17
+00:01:29,570 --> 00:01:32,970
+المجاورة
+
+18
+00:01:32,970 --> 00:01:37,800
+المجاورة بالضبط، فإن زي زي زي زي زي زي زي زي زي زي زي
+
+19
+00:01:37,800 --> 00:01:39,980
+زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي
+
+20
+00:01:39,980 --> 00:01:41,740
+زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي
+
+21
+00:01:41,740 --> 00:01:46,240
+زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي زي
+
+22
+00:01:46,240 --> 00:01:51,960
+زي زي زي زي زي زي زي زي زي زي
+
+23
+00:01:51,960 --> 00:02:03,600
+زي
+
+24
+00:02:12,560 --> 00:02:19,440
+أولًا، إذا أزمة الحكومة أزمة الحكومة إضافية، ستتغير
+
+25
+00:02:19,440 --> 00:02:22,900
+أسعار التطبيق المجاور للحكومة المجاور للحكومة
+
+26
+00:02:22,900 --> 00:02:26,160
+المجاور للحكومة المجاور للحكومة المجاور للحكومة
+
+27
+00:02:26,160 --> 00:02:29,710
+المجاور للحكومة المجاور ماذا بالنسبالي لـ Expansion
+
+28
+00:02:29,710 --> 00:02:34,610
+Policy؟ تقسيم أسعار الأموال تقسيم أسعار الأموال
+
+29
+00:02:34,610 --> 00:02:36,990
+تقسيم أسعار الأموال تقسيم أسعار الأموال تقسيم
+
+30
+00:02:36,990 --> 00:02:41,430
+أسعار الأموال تقسيم أسعار الأموال تقسيم أسعار
+
+31
+00:02:41,430 --> 00:02:41,870
+الأموال تقسيم أسعار الأموال تقسيم أسعار الأموال
+
+32
+00:02:41,870 --> 00:02:42,910
+تقسيم أسعار الأموال تقسيم أسعار الأموال تقسيم
+
+33
+00:02:42,910 --> 00:02:46,510
+أسعار الأموال تقسيم أسعار الأموال تقسيم أسعار
+
+34
+00:02:46,510 --> 00:02:51,230
+الأموال تقسيم أسعار الأموال تقسيم أسعار الأموال
+
+35
+00:02:51,230 --> 00:02:53,450
+تقسيم أسعار الأموال تقسيم
+
+36
+00:02:56,020 --> 00:03:05,660
+مثلًا إذا قررت الشركة تقوم بإزالة تجارب الدفع، هذا
+
+37
+00:03:05,660 --> 00:03:12,520
+يجعلها تقوم بإزالة تجارب الدفع، هذا يجعلها تقوم
+
+38
+00:03:12,520 --> 00:03:16,420
+بإزالة تجارب الدفع، هذا يجعلها تقوم بإزالة تجارب
+
+39
+00:03:16,420 --> 00:03:22,580
+الدفع، لذلك، هناك علاقة عكسية بين قيمة التخزين
+
+40
+00:03:22,580 --> 00:03:27,500
+والتطبيق التجاري والتطبيق
+
+41
+00:03:27,500 --> 00:03:28,420
+التجاري والتطبيق التجاري والتطبيق التجاري والتطبيق
+
+42
+00:03:28,420 --> 00:03:29,840
+التجاري والتطبيق التجاري والتطبيق التجاري والتطبيق
+
+43
+00:03:29,840 --> 00:03:30,360
+التجاري والتطبيق التجاري والتطبيق التجاري والتطبيق
+
+44
+00:03:30,360 --> 00:03:30,800
+التجاري والتطبيق التجاري والتطبيق التجاري والتطبيق
+
+45
+00:03:30,800 --> 00:03:31,320
+التجاري والتطبيق التجاري والتطبيق التجاري والتطبيق
+
+46
+00:03:31,320 --> 00:03:36,780
+التجاري والتطبيق التجاري والتطبيق التجاري والتطبيق
+
+47
+00:03:37,080 --> 00:03:40,680
+وهو يؤدي إلى تقسيم المعادلة لأن هناك علاقة عكسية
+
+48
+00:03:40,680 --> 00:03:45,040
+بين المعادلة ومقارنة الاحتياطات التي يؤدي إلى نفس
+
+49
+00:03:45,040 --> 00:03:51,360
+الاتجاه الاتجاه المزيد من R تقسيم I وأخيرًا تقسيم
+
+50
+00:03:51,360 --> 00:03:56,360
+المطالب المجتمعي لذا هناك علاقة عكسية بين مقارنة
+
+51
+00:03:56,360 --> 00:04:00,100
+الاحتياطات والمطالب المجتمعي ماذا عن شرائح الشرائح
+
+52
+00:04:00,100 --> 00:04:06,090
+أو شرائح الشرائح أو حكومات الحكومة بالتالي، الـ
+
+53
+00:04:06,090 --> 00:04:11,170
+Buying Bonds يقوم
+
+54
+00:04:11,170 --> 00:04:17,730
+بإزالة المساعدة المالية وإزالة الـ R وإزالة I
+
+55
+00:04:17,730 --> 00:04:21,610
+وإزالة المطالب المجاور للمطالب المجاور للمطالب
+
+56
+00:04:21,610 --> 00:04:25,530
+المجاور للمطالب المجاور للمطالب المجاور للمطالب
+
+57
+00:04:25,530 --> 00:04:29,530
+المجاور للمطالب المجاور للمطالب المجاور للمطالب
+
+58
+00:04:29,530 --> 00:04:31,910
+المجاور للمطالب المجاور للمطالب المجاور للمطالب
+
+59
+00:04:31,910 --> 00:04:33,270
+المجاور للمطالب المجاور للمطالب المجاور للمطالب
+
+60
+00:04:33,270 --> 00:04:36,300
+المجاور للمطالب المجاور للمطالب المجـ  الأسلحة تتسبب
+
+61
+00:04:36,300 --> 00:04:40,120
+في انتقال ومطالبة المجتمع، فكل الأسئلة التالية
+
+62
+00:04:40,120 --> 00:04:49,480
+ستتحدث عن هذه الأشياء وتحليلها، صحيح؟ ماذا عن 
+
+63
+00:04:49,480 --> 00:04:56,940
+الأسعار ومقاومة المجتمع المطالب؟ تزيد الأسعار وهذا
+
+64
+00:04:56,940 --> 00:05:02,160
+يؤدي إلى تقليل في مجموعات الانتجار المطلوبة لكي
+
+65
+00:05:02,160 --> 00:05:09,530
+نعمل على نفس المطالبة المطلوبة يعني الزيادة في
+
+66
+00:05:09,530 --> 00:05:14,190
+الأسعار تؤدي إلى انخفاض في الكمية المطلوبة الكلية So
+
+67
+00:05:14,190 --> 00:05:18,190
+we will still work along the same demand curve
+
+68
+00:05:18,190 --> 00:05:22,710
+Yes, the same But these changes in the required
+
+69
+00:05:22,710 --> 00:05:25,190
+reserve ratio, the discount rate, the government
+
+70
+00:05:25,190 --> 00:05:28,090
+spending, the net taxes What about the net taxes?
+
+71
+00:05:28,850 --> 00:05:32,390
+Net taxes, increasing the net taxes
+
+72
+00:05:35,140 --> 00:05:40,080
+هو يتسبب في نفس التأثير على تقليل المستوى الذي
+
+73
+00:05:40,080 --> 00:05:45,470
+يتسبب في تقليل المستوى المجتمعي for sure إن زيادة
+
+74
+00:05:45,470 --> 00:05:49,150
+الضرائب حد قلق الطلب بالكلية صح؟ and vice versa
+
+75
+00:05:49,150 --> 00:05:51,990
+for sure so this question is the aggregate demand
+
+76
+00:05:51,990 --> 00:05:55,110
+curve would shift to the left if what? if the net
+
+77
+00:05:55,110 --> 00:06:00,670
+taxes were increased and in this exercise or this
+
+78
+00:06:00,670 --> 00:06:03,890
+example a decrease in the net taxes leads to what?
+
+79
+00:06:03,930 --> 00:06:07,930
+increasing aggregate demand صح؟ طيب a rightward
+
+80
+00:06:07,930 --> 00:06:10,250
+shifting in the aggregate demand curve could be
+
+81
+00:06:10,250 --> 00:06:13,590
+caused by what? by the federal buying bonds
+
+82
+00:06:17,490 --> 00:06:20,930
+لنذهب إلى هذا البرنامج البرنامج البرنامج البرنامج
+
+83
+00:06:20,930 --> 00:06:21,650
+البرنامج البرنامج البرنامج البرنامج البرنامج
+
+84
+00:06:21,650 --> 00:06:27,610
+البرنامج البرنامج البرنامج البرنامج البرنامج
+
+85
+00:06:27,610 --> 00:06:28,450
+البرنامج البرنامج البرنامج البرنامج البرنامج
+
+86
+00:06:28,450 --> 00:06:32,050
+البرنامج البرنامج البرنامج البرنامج البرنامج
+
+87
+00:06:32,050 --> 00:06:32,390
+البرنامج البرنامج البرنامج البرنامج البرنامج
+
+88
+00:06:32,390 --> 00:06:43,750
+البرنامج البرنامج البرنامج البرنامج البرنا
+
+89
+00:06:44,660 --> 00:06:50,220
+لا، السعر يتأثر أو يتغير من A إلى E أو A إلى D
+
+90
+00:06:50,220 --> 00:06:56,820
+ولكن التغيير من A إلى B يمكن أن يكون مسبقًا من
+
+91
+00:06:56,820 --> 00:07:03,140
+ماذا محمد؟ بالضبط،  إزعاج الحكومة، إزعاج مصادر
+
+92
+00:07:03,140 --> 00:07:06,420
+الدولة، إزعاج عمليات الدولة، إزعاج عمليات الدولة
+
+93
+00:07:08,530 --> 00:07:13,090
+بالضبط، فهذه هي السبب الرئيسية لتغيير كلمة صحيحة
+
+94
+00:07:13,090 --> 00:07:17,830
+في المجتمع التجاري أو من A إلى B ومن هناك من B 
+
+95
+00:07:17,830 --> 00:07:23,850
+إلى A ولكن ماذا عن التغيير أو التدخل من A إلى E؟
+
+96
+00:07:23,850 --> 00:07:31,790
+ربما يسبب فيه زيادة في مستوى السعر لا، المال يؤثر
+
+97
+00:07:31,790 --> 00:07:35,750
+على طلب المال ثم حركة الهدف، لذلك نحن لدينا تغيير 
+
+98
+00:07:35,750 --> 00:07:41,050
+اليسار أو تغيير اليسار أو تغيير المال، لذلك دعونا
+
+99
+00:07:41,050 --> 00:07:45,950
+نذهب إلى التعليمات ونتحدث
+
+100
+00:07:45,950 --> 00:07:50,860
+عن الفيجور، مطالبة طلب Shifts or shift from
+
+101
+00:07:50,860 --> 00:07:53,920
+aggregate demand 2 to aggregate demand 0 can be
+
+102
+00:07:53,920 --> 00:07:57,060
+caused by what؟ هذا اللي ناقشناه اللي جيت أنه بدأ
+
+103
+00:07:57,060 --> 00:08:01,360
+انتقل من هنا لهنا maybe by what أو from aggregate
+
+104
+00:08:01,360 --> 00:08:06,180
+demand 1 to 0 by what؟ okay so we have the
+
+105
+00:08:06,180 --> 00:08:10,260
+shifting from aggregate demand 1 to 0 may be
+
+106
+00:08:10,260 --> 00:08:12,640
+caused by decrease in the government spending اللي
+
+107
+00:08:12,640 --> 00:08:19,690
+هو leftward shifting العامة في نقطة A. العامة في
+
+108
+00:08:19,690 --> 00:08:33,950
+نقطة A. العامة في نقطة A. العامة
+
+109
+00:08:33,950 --> 00:08:44,520
+في نقطة A. العامة في نقطة A. العامة في نقطة التقرير
+
+110
+00:08:44,520 --> 00:08:50,120
+في مقالات الأسعار ربما يتسبب في تحويل إلى نقطة D
+
+111
+00:08:50,120 --> 00:08:57,880
+إذا كانت
+
+112
+00:08:57,880 --> 00:09:02,600
+الاقتصاد في نقطة A فإن زيادة المال يمكن أن يسبب
+
+113
+00:09:02,600 --> 00:09:06,940
+فيه حركة تحويل إلى نقطة ماذا؟ فالتحويل في المال
+
+114
+00:09:06,940 --> 00:09:08,100
+يتسبب في تحويل المال
+
+115
+00:09:13,230 --> 00:09:18,550
+أنا لا أعرف، يجب أن نتعامل مع ذلك، فإننا نكون في
+
+116
+00:09:18,550 --> 00:09:27,330
+نقطة A، فالمزيد في مالي ديمان يدفع إلى ما يدفع في
+
+117
+00:09:27,330 --> 00:09:30,990
+R يدفع
+
+118
+00:09:30,990 --> 00:09:36,970
+إلى المزيد R Decrease I Decrease Aggregate
+
+119
+00:09:36,970 --> 00:09:39,390
+Exponential and Aggregate Demand So there is a
+
+120
+00:09:39,390 --> 00:09:41,730
+leftward shifting in the aggregate demand curve So
+
+121
+00:09:41,730 --> 00:09:48,090
+we will shift to point C Let's come back هذا يعني
+
+122
+00:09:48,090 --> 00:09:50,730
+ليش؟ Leftward shifting Suppose that we are at
+
+123
+00:09:50,730 --> 00:09:54,710
+point A There is a leftward shifting to point C
+
+124
+00:09:54,710 --> 00:09:56,110
+صح؟
+
+125
+00:10:02,490 --> 00:10:07,730
+اعتبار نحن في نقطة A فإن اتخاذ الحكومة يتخذ على
+
+126
+00:10:07,730 --> 00:10:19,550
+منحنى ثاني على الـ C صح؟ صح أو خاطئ؟ اتخاذ اتخاذ
+
+127
+00:10:19,550 --> 00:10:22,470
+اتخاذ اتخاذ اتخاذ اتخاذ اتخذ اتخذ اتخذ اتخذ اتخذ
+
+128
+00:10:22,470 --> 00:10:23,530
+اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ
+
+129
+00:10:23,530 --> 00:10:24,570
+اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ
+
+130
+00:10:24,570 --> 00:10:28,330
+اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ اتخذ
+
+131
+00:10:28,330 --> 00:10:38,760
+اتخذ اتخذ اتـ صح؟ okay exactly number two a decrease
+
+132
+00:10:38,760 --> 00:10:41,960
+in the net taxes or taxation increases the
+
+133
+00:10:41,960 --> 00:10:46,940
+aggregate demand صح ولا غلط صح true a decrease in
+
+134
+00:10:46,940 --> 00:10:51,340
+the price level raises the real value of wealth الـ
+
+135
+00:10:51,340 --> 00:10:55,420
+prices لما بتنزل real wealth ثروتك الحقيقي بتزيد
+
+136
+00:10:55,420 --> 00:11:02,410
+it's true المزيد من المال يتحول إلى ما يحتاجه
+
+137
+00:11:02,410 --> 00:11:07,030
+الشركة للحصول على المساعدة، لأن المزيد من المال
+
+138
+00:11:07,030 --> 00:11:08,550
+يتحول إلى ما يحتاجه الشركة للحصول على المساعدة،
+
+139
+00:11:08,550 --> 00:11:09,550
+لأن المزيد من المال يتحول إلى ما يحتاجه الشركة
+
+140
+00:11:09,550 --> 00:11:13,130
+للحصول على المساعدة، لأن المزيد من المال يتحول إلى 
+
+141
+00:11:13,130 --> 00:11:14,210
+ما يحتاجه الشركة للحصول على المساعدة، لأن المزيد
+
+142
+00:11:14,210 --> 00:11:15,590
+من المال يتحول إلى ما يحتاجه الشركة للحصول على 
+
+143
+00:11:15,590 --> 00:11:19,850
+المساعدة، Okay, true, the aggregate demand curve
+
+144
+00:11:19,850 --> 00:11:23,610
+shows that at higher price levels, اللي ما بتكون 
+
+145
+00:11:23,610 --> 00:11:26,810
+الأسعار عالية، the total quantity of output 
+
+146
+00:11:26,810 --> 00:11:32,410
+demanded is greater، بتزيد، غلط، okay. If the
+
+147
+00:11:32,410 --> 00:11:35,910
+federal government buys securities، إذا رايحين
+
+148
+00:11:35,910 --> 00:11:39,270
+مشتريين bonds، the money supply بيزيد، وبالتالي،
+
+149
+00:11:39,270 --> 00:11:42,110
+أنا اللي بقوله أنه decrease في the money supply،
+
+150
+00:11:42,110 --> 00:11:46,620
+غلط. هذا يؤدي إلى زيادة في المساعدة والتطبيق التجاري
+
+151
+00:11:46,620 --> 00:11:52,220
+والتطبيق 
+
+152
+00:11:52,220 --> 00:11:56,760
+التجاري يتسبب في زيادة في الأسعار بالزيادة في
+
+153
+00:11:56,760 --> 00:12:03,700
+التطبيق التجاري لإزالة تطبيق التجاري لإزالة تطبيق 
+
+154
+00:12:03,700 --> 00:12:05,600
+التجاري لإزالة تطبيق التجاري لإزالة تطبيق التجاري
+
+155
+00:12:05,600 --> 00:12:07,200
+لإزالة تطبيق التجاري لإزالة تطبيق التجاري لإزالة
+
+156
+00:12:07,200 --> 00:12:07,240
+تطبيق التجاري لإزالة تطبيق التجاري لإزالة تطبيق
+
+157
+00:12:07,240 --> 00:12:08,360
+التجاري لإزالة تطبيق التجاري لإزالة تطبيق التجاري
+
+158
+00:12:08,360 --> 00:12:12,600
+لإزالة تطبيق التجاري لإزالة تعلى نقطة أو في تنمية
+
+159
+00:12:12,600 --> 00:12:22,660
+1500 دولار إذا كنا
+
+160
+00:12:22,660 --> 00:12:31,880
+نعمل على نقطة 500 أو Y 500 أنها كما تعلم أنها تحت 
+
+161
+00:12:31,880 --> 00:12:36,940
+المقاومة تحت مقاومة الانفجار إذا ارتفع المساعدة 
+
+162
+00:12:36,940 --> 00:12:37,300
+العامة
+
+163
+00:12:40,200 --> 00:12:42,680
+عن طريق aggregate demand 1 إلى aggregate demand 2
+
+164
+00:12:42,680 --> 00:12:48,360
+هذا يؤدي إلى إيش؟ هذا يؤدي إلى زيادة ميزة
+
+165
+00:12:48,360 --> 00:12:54,140
+aggregate output وميزة aggregate output، صح؟
+
+166
+00:12:54,140 --> 00:13:07,000
+مظبوط؟ طيب، فإننا نعمل في مقفل أو قريب من القدرة أو 
+
+167
+00:13:07,000 --> 00:13:11,340
+القدرة الكاملة نحن قريب من القدرة الكاملة يعني اعتبر
+
+168
+00:13:11,340 --> 00:13:17,320
+أننا نشتغل هنا at one thousand two hundred، صح؟
+
+169
+00:13:17,320 --> 00:13:20,320
+الانزعاج من الأسعار الأسعار الأسعار الثلاثة إلى 
+
+170
+00:13:20,320 --> 00:13:26,220
+الأسعار الأسعار الأربعة يؤدي إلى ماذا؟ انزعاج أعلى
+
+171
+00:13:26,220 --> 00:13:32,870
+في الأسعار مع انزعاج صغير في الواحد right. طب وين
+
+172
+00:13:32,870 --> 00:13:40,370
+بتكون the fiscal policy is more effective هان
+
+173
+00:13:40,370 --> 00:13:47,070
+ولا هان in the first exactly when the aggregate
+
+174
+00:13:47,070 --> 00:13:53,010
+supply is close to a horizontal line لما بيكون قريب
+
+175
+00:13:53,010 --> 00:13:57,090
+من the horizontal line in this case الخصائص التجارية
+
+176
+00:13:57,090 --> 00:14:02,770
+والتجارب التجارية ستكون أكثر مفيدة، لكن هنا يجب أن
+
+177
+00:14:02,770 --> 00:14:05,970
+تكون أقل مفيدة في الوضع
+
+178
+00:14:11,290 --> 00:14:15,390
+والحكومة قررت أن تزيد مستقبلها أو تستخدم اتفاق
+
+179
+00:14:15,390 --> 00:14:17,110
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+180
+00:14:17,110 --> 00:14:17,570
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+181
+00:14:17,570 --> 00:14:25,730
+اتفاق اتفاق اتفاق اتفاق
+
+182
+00:14:25,730 --> 00:14:27,650
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+183
+00:14:27,650 --> 00:14:27,750
+اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق اتفاق
+
+184
+00:14:27,750 --> 00:14:30,530
+اتفاق اتفاق اتفاق
+
+185
+00:14:40,780 --> 00:14:45,000
+انفلايشناري gap صح؟ because we have only
+
+186
+00:14:45,000 --> 00:14:49,920
+increasing the price level، that's it، مظبوط؟ اللي
+
+187
+00:14:49,920 --> 00:14:52,120
+بعد عند النقطة the full capacity هنا، عند النقطة
+
+188
+00:14:52,120 --> 00:14:54,920
+أمن، شو الزيادة اللي في the aggregate demand عملات؟
+
+189
+00:14:54,920 --> 00:14:59,220
+ولا حاجة، increasing the prices، بس، صح؟ but with
+
+190
+00:14:59,220 --> 00:15:05,660
+no change in Y، so is or does the fiscal policy 
+
+191
+00:15:05,660 --> 00:15:10,700
+effective or not؟ إنها ليست مفيدة بالضبط ماذا 
+
+192
+00:15:10,700 --> 00:15:12,300
+بالنسبة لي لقوة the Monetary policy في هذه الحالة؟
+
+193
+00:15:12,300 --> 00:15:15,580
+أعتقد أن هذه الشركة تزيد مصادر المال، ستزيد مصادر
+
+194
+00:15:15,580 --> 00:15:18,920
+المال الاقتصادي، ولكن ليس هناك تغيير في الواقع.
+
+195
+00:15:19,260 --> 00:15:22,880
+لذا، هل هي قوة the Monetary policy مفيدة أو لا؟
+
+196
+00:15:22,880 --> 00:15:28,680
+ليست مفيدة. تمام؟ تمام، طيب، لدي سؤال آخر، أعتقد
+
+197
+00:15:28,680 --> 00:15:32,120
+أننا في موقع K هنا، 
+
+198
+00:15:36,410 --> 00:15:45,930
+الحكومة قررت تقليل عملياتها هل 
+
+199
+00:15:45,930 --> 00:15:54,540
+لدينا محادثة؟ لا لأن لماذا يبقى مستمر؟ طب what
+
+200
+00:15:54,540 --> 00:15:57,260
+would happen to the unemployment if the government
+
+201
+00:15:57,260 --> 00:15:59,940
+decided to decrease its spending؟ يعني إذا كنا عند
+
+202
+00:15:59,940 --> 00:16:03,840
+الجهة ورحنا مزودين، this is aggregate demand four
+
+203
+00:16:03,840 --> 00:16:08,240
+and the government five and the government decided
+
+204
+00:16:08,240 --> 00:16:11,140
+to use a contractionary fiscal policy by 
+
+205
+00:16:11,140 --> 00:16:13,840
+decreasing the government spending or increasing
+
+206
+00:16:13,840 --> 00:16:18,740
+ديال التاكسز، راحوا مجللين الإنفاق تبعهم what
+
+207
+00:16:18,740 --> 00:16:21,220
+would happen to the unemployment rate؟
+
+208
+00:16:28,560 --> 00:16:33,720
+Exactly because at this point point k here if we
+
+209
+00:16:33,720 --> 00:16:37,540
+are we work we are we are working over the full
+
+210
+00:16:37,540 --> 00:16:42,160
+capacity or above the full capacity so in this
+
+211
+00:16:42,160 --> 00:16:45,700
+case if the government used a contraction of
+
+212
+00:16:45,700 --> 00:16:47,580
+fiscal policy by decreasing the government
+
+213
+00:16:47,580 --> 00:16:52,500
+spending or increase the taxes or the net taxes
+
+214
+00:16:52,500 --> 00:16:55,080
+should be seen the aggregate demand would decline
+
+215
+00:17:10,530 --> 00:17:22,490
+بس هان suppose we work at point F in 
+
+216
+00:17:22,490 --> 00:17:26,690
+this case إذا كانت الحكومة تستخدم قياسية تخزينية
+
+217
+00:17:26,690 --> 00:17:29,190
+تخزينية تخزينية تخزينية تخزينية تخزينية تخزينية
+
+218
+00:17:29,190 --> 00:17:30,210
+تخزينية تخزينية تخزينية تخزينية تخزينية تخزينية
+
+219
+00:17:30,210 --> 00:17:33,870
+تخزينية تخزينية تخزينية تخزينية تخزينية تخزينية
+
+220
+00:17:33,870 --> 00:17:38,090
+تخزينية
+
+221
+00:17:38,090 --> 00:17:40,910
+تخزينية تخزينية تخزينية تخزينية تخزينية تخزينية
+
+222
+00:17:40,910 --> 00:17:41,450
+تخزينية تخزينية تخزينية تخزينية تخزينية تخزينية
+
+223
+00:17:41,450 --> 00:17:41,730
+تخزينية تخزينية تخزينية تخزينية تخزينية تخزينية
+
+224
+00:17:41,730 --> 00:17:52,230
+تخزينية تخزينية تخزينية تخز
+
+225
+00:17:53,570 --> 00:17:56,690
+Why would decline and unemployment rate would
+
+226
+00:17:56,690 --> 00:18:00,690
+increase? Because we worked below the full capacity.
+
+227
+00:18:00,690 --> 00:18:07,250
+Okay, but after the full capacity, any
+
+228
+00:18:07,250 --> 00:18:09,950
+increasing or decreasing the government spending
+
+229
+00:18:09,950 --> 00:18:12,670
+would not change. Why? So it would not change the
+
+230
+00:18:12,670 --> 00:18:16,690
+recession, would not change the unemployment. صح؟
+
+231
+00:18:16,690 --> 00:18:19,970
+طب شو the relationship ما بين the unemployment و ال
+
+232
+00:18:19,970 --> 00:18:26,800
+output, aggregate output؟ انفرس بالضبط، صحيح؟ طيب،
+
+233
+00:18:26,800 --> 00:18:29,460
+لنذهب إلى الأسئلة أو الأمور
+
+234
+00:18:38,240 --> 00:18:42,360
+بالعكس، ماهي العلاقة ما بين the 500 باليون والـ1000
+
+235
+00:18:42,360 --> 00:18:49,200
+باليون والعلاقة ما بين قيمة the 500 والـ1000
+
+236
+00:18:49,200 --> 00:18:51,600
+والعلاقة ما بين قيمة the 500 والـ1000 والعلاقة ما
+
+237
+00:18:51,600 --> 00:18:51,660
+بين قيمة the 500 والـ1000 والعلاقة ما بين قيمة
+
+238
+00:18:51,660 --> 00:18:51,700
+the 500 والـ1000 والعلاقة ما بين قيمة the 500
+
+239
+00:18:51,700 --> 00:18:51,740
+والـ1000 والعلاقة ما بين قيمة the 500 والـ1000
+
+240
+00:18:51,740 --> 00:18:52,960
+والعلاقة ما بين قيمة the 500 والـ1000 والعلاقة ما
+
+241
+00:18:52,960 --> 00:18:53,580
+بين قيمة the 500 والعلاقة ما بين قيمة the 500
+
+242
+00:18:53,580 --> 00:18:56,580
+the 500 والعلاقة ما بين قيمة the 500 والعلاقة ما بين
+
+243
+00:18:56,580 --> 00:18:59,880
+قيمة the 500 والعلاقة ما بين قيمة the 500 والعلاقة
+
+244
+00:18:59,880 --> 00:19:04,230
+ما بين قيمة تمام؟ So the relationship between the 
+
+245
+00:19:04,230 --> 00:19:09,230
+aggregate output and the price level is positive
+
+246
+00:19:09,230 --> 00:19:15,910
+طيب، what else؟ This economy reaches full capacity at
+
+247
+00:19:15,910 --> 00:19:22,270
+قداش؟ 1500، صحيح؟
+
+248
+00:19:22,270 --> 00:19:24,550
+Okay, when the aggregate supply curve is a
+
+249
+00:19:24,550 --> 00:19:30,600
+vertical which of the following is not true؟ إذا 
+
+250
+00:19:30,600 --> 00:19:34,780
+كان منحنى the aggregate supply عمودي، vertical، 
+
+251
+00:19:34,780 --> 00:19:39,440
+الألومن هدولة مش صحيحة. دي اللي the economy is
+
+252
+00:19:39,440 --> 00:19:43,220
+expanding quickly.  the there is no change in the
+
+253
+00:19:43,220 --> 00:19:45,300
+economy in this case. صحى اللي it should be
+
+254
+00:19:45,300 --> 00:19:49,920
+constant. طيب if the economy is operating on the
+
+255
+00:19:49,920 --> 00:19:53,360
+relatively vertical segment يعني الاقتصاد شغال 
+
+256
+00:19:53,360 --> 00:19:56,260
+قريب من the full capacity يعني مش واصل لسه the full
+
+257
+00:19:56,260 --> 00:20:00,270
+capacity بس قريب منه of the aggregate supply curve 
+
+258
+00:20:00,270 --> 00:20:03,670
+and an increase in the aggregate demand curve الزيادة
+
+259
+00:20:03,670 --> 00:20:05,930
+cause what؟ يعني الزيادة اللي بتصير في aggregate
+
+260
+00:20:05,930 --> 00:20:09,810
+demand شو بتعمل؟ فراغة change in the price level
+
+261
+00:20:09,810 --> 00:20:12,930
+and فراغة change in output يعني سببز إذا ارجع شوي
+
+262
+00:20:12,930 --> 00:20:17,590
+هيك احنا قريبين من the full capacity يعني نشتغل هنا 
+
+263
+00:20:17,590 --> 00:20:21,310
+هيك بيقولنا ان the increase في aggregate demand
+
+264
+00:20:24,060 --> 00:20:29,080
+ماذا تفعل؟ تقوم
+
+265
+00:20:29,080 --> 00:20:33,880
+بتغيير كبير في السعر لتغيير أصغر في الوعي
+
+266
+00:20:37,170 --> 00:20:41,610
+Okay, if the economy is operating way below 
+
+267
+00:20:41,610 --> 00:20:45,270
+capacity, below capacity means هنا بيقصد أنه في 
+
+268
+00:20:45,270 --> 00:20:47,790
+منطقة اللي هي قريب بيكون horizontal line the 
+
+269
+00:20:47,790 --> 00:20:50,970
+aggregate اي expenditure بيكون قريب من الأفق يعني،
+
+270
+00:20:50,970 --> 00:20:53,590
+على مين بيكون فيه زيادة؟ وعنا the aggregate demand 
+
+271
+00:20:53,590 --> 00:20:59,160
+زاد شو بيعمل؟ exactly في هنا small increase في the
+
+272
+00:20:59,160 --> 00:21:03,020
+prices and large increase في the aggregate output
+
+273
+00:21:03,020 --> 00:21:06,880
+يعني هدف وين؟ exactly بتكون the expansion fiscal
+
+274
+00:21:06,880 --> 00:21:09,580
+policy and monetary policy is effective هذا لما
+
+275
+00:21:09,580 --> 00:21:12,340
+بيكون وين؟ لما يكون the aggregate supply جاي
+
+276
+00:21:12,340 --> 00:21:15,560
+horizontal line أو قريب من the horizontal يعني أو
+
+277
+00:21:15,560 --> 00:21:18,440
+مش واصل the .. the .. the capacity يعني في المرحلة the 
+
+278
+00:21:18,440 --> 00:21:24,030
+.. the .. القريب يعني طيب the increase an increase in
+
+279
+00:21:24,030 --> 00:21:26,550
+the aggregate demand when the economy is operating
+
+280
+00:21:26,550 --> 00:21:33,730
+at a high level of output is likely to result in هلأ لما 
+
+281
+00:21:33,730 --> 00:21:38,490
+بيكون إحنا الـ aggregate output عالي كتير شو اللي
+
+282
+00:21:38,490 --> 00:21:42,430
+بيصير؟ بيه بس بيه شو هي؟ An increase in the
+
+283
+00:21:42,430 --> 00:21:45,090
+overall price level but little or no increase in
+
+284
+00:21:45,090 --> 00:21:50,490
+output خلينا نرجع لها نرجع لها؟ هيولأ هو بيقولنا 
+
+285
+00:21:50,490 --> 00:21:55,110
+إنه إحنا إذا كان الـ economy بيشتغل near the
+
+286
+00:21:55,110 --> 00:21:59,010
+capacity يعني قريب من الـ capacity يعني يا إما مهان
+
+287
+00:21:59,010 --> 00:22:03,910
+هيك أو مهان في المناطق هذه شو الوضع؟ الـ increasing
+
+288
+00:22:03,910 --> 00:22:10,250
+في الـ aggregate demand بيزيد الـ prices with a
+
+289
+00:22:10,250 --> 00:22:15,370
+small why يا إما بيكون في عنده small change أو لما
+
+290
+00:22:15,370 --> 00:22:18,090
+بيكون واصل هنا في المنطقة الـ full capacity no
+
+291
+00:22:18,090 --> 00:22:18,470
+change
+
+292
+00:22:21,750 --> 00:22:26,850
+Okay when the economy is operating at full
+
+293
+00:22:26,850 --> 00:22:31,750
+capacity is likely result to what؟ طبعا هيكون in
+
+294
+00:22:31,750 --> 00:22:35,370
+the increasing flip prices with no change in why؟
+
+295
+00:22:35,370 --> 00:22:38,450
+هذا وين؟ at full capacity يعني نقطة الـ full
+
+296
+00:22:38,450 --> 00:22:44,320
+capacity exactly اللي بتعمل .. it would create the
+
+297
+00:22:44,320 --> 00:22:48,200
+inflationary gap problem طيب when the economy is
+
+298
+00:22:48,200 --> 00:22:50,600
+producing at full capacity the aggregate supply
+
+299
+00:22:50,600 --> 00:22:55,860
+curve becomes what؟ vertical yes طيب let's go ..
+
+300
+00:22:55,860 --> 00:22:56,080
+yes
+
+301
+00:23:16,790 --> 00:23:26,430
+Sustained Inflation بيعمل
+
+302
+00:23:26,430 --> 00:23:26,570
+بيعمل بيعمل بيعمل بيعمل بيعمل بيعمل بيعمل بيعمل
+
+303
+00:23:26,570 --> 00:23:27,330
+بيعمل بيعمل بيعمل بيعمل بيعمل بيعمل بيعمل بيعمل
+
+304
+00:23:27,330 --> 00:23:30,780
+بيعمل بيعمل بيعمل بيعمل بيعمل بيلنذهب الى
+
+305
+00:23:30,780 --> 00:23:40,780
+التعليمات أو زيادة في الـ aggregate supply تمثل
+
+306
+00:23:40,780 --> 00:23:43,900
+بانتقال من أين لأين من aggregate supply one to
+
+307
+00:23:43,900 --> 00:23:47,060
+aggregate supply zero أو من aggregate supply two
+
+308
+00:23:47,060 --> 00:23:49,720
+to aggregate supply one أو من aggregate supply two
+
+309
+00:23:49,720 --> 00:23:53,720
+to zero أو من aggregate supply one to aggregate
+
+310
+00:23:53,720 --> 00:23:55,180
+supply zero أو من aggregate supply two to
+
+311
+00:23:55,180 --> 00:23:55,700
+one to aggregate supply zero أو من aggregate
+
+312
+00:23:55,700 --> 00:23:58,200
+supply one to aggregate supply zero 
+
+313
+00:24:02,810 --> 00:24:06,590
+التحديد في المصادر التجارية موضوع الـ backward
+
+314
+00:24:06,590 --> 00:24:09,290
+-shifting أو الـ leftward-shifting في المصادر
+
+315
+00:24:20,180 --> 00:24:23,000
+let's go to this .. or to the exercise .. suppose
+
+316
+00:24:23,000 --> 00:24:26,980
+the economy is at point A .. suppose إن إحنا وين؟
+
+317
+00:24:26,980 --> 00:24:31,140
+عند point A .. تمام؟ إشوط فيه .. and the increase
+
+318
+00:24:31,140 --> 00:24:35,560
+or .. the increase in the price level .. الزيادة
+
+319
+00:24:35,560 --> 00:24:41,040
+في الأسعار بوديني أين؟ from A to B here .. along
+
+320
+00:24:41,040 --> 00:24:43,580
+the same aggregate supply curve طب الـ decreasing
+
+321
+00:24:43,580 --> 00:24:48,520
+في الـ prices وين بوديني؟ على C exactly صحيح صحيح؟
+
+322
+00:24:48,520 --> 00:24:53,900
+طيب طيب الـ .. the shifting from A to E decrease ..
+
+323
+00:24:53,900 --> 00:24:57,820
+decrease in diagonal supply أكيد but what are the
+
+324
+00:24:57,820 --> 00:25:03,720
+main reasons or causes for this? maybe the wages
+
+325
+00:25:03,720 --> 00:25:09,080
+increase .. the wages exactly maybe the cost of
+
+326
+00:25:09,080 --> 00:25:12,180
+production increase when the cost of production
+
+327
+00:25:12,180 --> 00:25:12,880
+increase
+
+328
+00:25:15,270 --> 00:25:19,110
+القادة لصنع أكثر و أكثر ستتخلص، لذلك ستتغير
+
+329
+00:25:19,110 --> 00:25:25,710
+المصادر العامة، تتحرك، نعم، حسنا، السؤال لي هو،
+
+330
+00:25:25,710 --> 00:25:29,530
+تعتمد على أن الاقتصاد يعمل في نقطة A، صحيح؟
+
+331
+00:25:29,530 --> 00:25:33,350
+التغيير إلى نقطة E قد يتسبب في ماذا؟
+
+332
+00:25:35,880 --> 00:25:39,460
+ممكن إنه زاد أو انتقلنا من aggregate supply 0 لـ
+
+333
+00:25:39,460 --> 00:25:41,900
+aggregate supply 2 لأن الـ cost production
+
+334
+00:25:41,900 --> 00:25:47,360
+increased أو الـ wages زادت maybe and vice versa
+
+335
+00:25:47,360 --> 00:25:53,920
+for sure طيب let's go to this diagram as you see
+
+336
+00:25:53,920 --> 00:25:57,740
+where is the equilibrium point؟
+
+337
+00:25:59,270 --> 00:26:05,250
+والدولار التجريبي هو 600 مليون دولار أو مليون
+
+338
+00:26:05,250 --> 00:26:06,350
+دولار أو مليون دولار أو مليون دولار أو مليون دولار
+
+339
+00:26:06,350 --> 00:26:13,550
+أو مليون دولار أو
+
+340
+00:26:13,550 --> 00:26:15,630
+مليون دولار
+
+341
+00:26:18,870 --> 00:26:22,530
+فراغ equilibrium output and for other prices اللي
+
+342
+00:26:22,530 --> 00:26:26,130
+لو استخدمنا expansionary monetary policy or maybe
+
+343
+00:26:26,130 --> 00:26:28,870
+increasing the money supply اللي لو روحنا مزودين
+
+344
+00:26:28,870 --> 00:26:33,600
+الـ money supply طبعا هذا بيعمل لو إن هو بيأثر على
+
+345
+00:26:33,600 --> 00:26:35,820
+الـ aggregate demand هذا this leads to increasing
+
+346
+00:26:35,820 --> 00:26:39,160
+the aggregate demand صح مش الـ increase في المناصب
+
+347
+00:26:39,160 --> 00:26:41,400
+طبعا شو بيعمل في aggregate demand بيساعده لأنه
+
+348
+00:26:41,400 --> 00:26:44,920
+should decrease R increase I increase aggregate
+
+349
+00:26:44,920 --> 00:26:48,480
+demand صح؟ so there is a rightward shifting in the
+
+350
+00:26:48,480 --> 00:26:50,820
+aggregate demand curve from aggregate demand one
+
+351
+00:26:50,820 --> 00:26:53,500
+to aggregate demand two which leads to increasing
+
+352
+00:26:53,500 --> 00:27:05,230
+prices increased in Y صح؟ هذا السؤال، so suppose
+
+353
+00:27:05,230 --> 00:27:09,370
+or they refer to the figure suppose the economy or
+
+354
+00:27:09,370 --> 00:27:12,590
+the equilibrium output is initially 600 billion, a
+
+355
+00:27:12,590 --> 00:27:16,090
+decrease in wages and increase in the government
+
+356
+00:27:16,090 --> 00:27:20,990
+spending، شو بيعمل؟ في الـ aggregate أقل هلا كنا عند
+
+357
+00:27:20,990 --> 00:27:23,870
+الـ initial عند الـ equilibrium تمام و الـ assumption
+
+358
+00:27:23,870 --> 00:27:27,430
+is إنه صار في عندي decrease في الـ wage أو في الـ
+
+359
+00:27:27,430 --> 00:27:31,090
+wages و increase في الـ government spending هذا شو
+
+360
+00:27:31,090 --> 00:27:35,810
+بيعمل let's do the analysis هلا السؤال إنه في عنده
+
+361
+00:27:35,810 --> 00:27:38,390
+two cases الأول إنه صار في عندي decreasing في الـ
+
+362
+00:27:38,390 --> 00:27:41,290
+wages و increasing في الـ government spending هلا
+
+363
+00:27:41,290 --> 00:27:42,250
+decreasing في الـ wages
+
+364
+00:27:46,700 --> 00:27:50,920
+increase or decrease the cost of production؟
+
+365
+00:27:50,920 --> 00:27:53,960
+increase aggregate supply increase aggregate
+
+366
+00:27:53,960 --> 00:27:56,620
+supply so there is a rightward shifting of the
+
+367
+00:27:56,620 --> 00:28:00,000
+aggregate supply curve صح؟ طيب الـ increasing اللي
+
+368
+00:28:00,000 --> 00:28:04,800
+صار في الـ governance funding شو قمت؟ increasing في
+
+369
+00:28:04,800 --> 00:28:09,460
+الـ governance funding increase aggregate demand طب
+
+370
+00:28:09,460 --> 00:28:11,380
+إذا صار في عندي increasing في الـ aggregate demand
+
+371
+00:28:11,380 --> 00:28:15,060
+و increasing في الـ aggregate supply طب شو اللي
+
+372
+00:28:15,060 --> 00:28:20,610
+صار؟ الآن اعتبر أن هناك ازالة في الـ aggregate
+
+373
+00:28:20,610 --> 00:28:24,750
+demand في هذه المسافة أكثر أكثر أكثر أكثر أكثر
+
+374
+00:28:24,750 --> 00:28:25,310
+أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر
+
+375
+00:28:25,310 --> 00:28:26,670
+أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر
+
+376
+00:28:26,670 --> 00:28:30,050
+أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر
+
+377
+00:28:30,050 --> 00:28:33,630
+أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر أكثر
+
+378
+00:28:33,630 --> 00:28:45,070
+أكثر أكثر أكثر أكثر أكثر 
+
+379
+00:28:46,410 --> 00:28:54,290
+الـ price increased هنا و الـ y increased طبعا طيب
+
+380
+00:28:54,290 --> 00:28:57,270
+لو فرضنا أن الزيادة اللي صارت في الـ aggregate
+
+381
+00:28:57,270 --> 00:29:01,030
+demand بتساوي الـ aggregate supply شو اللي صار الـ
+
+382
+00:29:01,030 --> 00:29:06,900
+price constant و الـ y increased صح؟ طيب لو كان الـ
+
+383
+00:29:06,900 --> 00:29:10,380
+aggregate supply الزيادة في aggregate supply أكبر
+
+384
+00:29:10,380 --> 00:29:13,120
+من الزيادة في aggregate demand الـ price would
+
+385
+00:29:13,120 --> 00:29:16,600
+decline و Y would increase so in all cases for
+
+386
+00:29:16,600 --> 00:29:22,900
+sure Y would increase صح؟ الـ price is ambiguous
+
+387
+00:29:22,900 --> 00:29:28,520
+exactly صحيح؟ طيب إذا إن هذا for sure إيش هيعمل؟
+
+388
+00:29:28,520 --> 00:29:32,980
+هيعمل لـ increasing the equilibrium output صح؟
+
+389
+00:29:34,350 --> 00:29:41,630
+من مش فاهم هاي النقطة؟ answer C صحيح اللي هو بيعمل
+
+390
+00:29:41,630 --> 00:29:45,510
+increasing في الـ equilibrium output طيب to
+
+391
+00:29:45,510 --> 00:29:49,030
+increase the price level عشان إن إحنا نزود الـ
+
+392
+00:29:49,030 --> 00:29:52,270
+price level the government could adapt policies
+
+393
+00:29:52,270 --> 00:29:57,630
+that what؟ عشان الـ government بدأ ترفع الـ prices
+
+394
+00:29:57,630 --> 00:30:05,330
+شو لازم تعمل؟ لازم إنهم يعملوا .. yes decreasing
+
+395
+00:30:05,330 --> 00:30:09,410
+agri supply or increase the agri demand صح ولا لأ؟
+
+396
+00:30:09,410 --> 00:30:12,290
+إذا يعملوا decreasing للـ agri supply and increase
+
+397
+00:30:12,290 --> 00:30:20,510
+agri demand تمام طب سؤال الـ .. suppose إن إحنا كنا
+
+398
+00:30:20,510 --> 00:30:25,710
+هان هيك، هاي درجة عليها لو بدنا نرفع الـ prices،
+
+399
+00:30:25,710 --> 00:30:28,830
+بدنا نزود الـ prices من 1000 لـ 1100، كيف ممكن نعمل؟
+
+400
+00:30:29,860 --> 00:30:32,860
+ممكن نزود الـ aggregate demand من aggregate demand
+
+401
+00:30:32,860 --> 00:30:35,820
+1 لـ aggregate demand 2 وبالتالي الـ process بتطلع،
+
+402
+00:30:35,820 --> 00:30:39,900
+صح؟ إذا in this case لازم الـ .. الـ .. الـ government
+
+403
+00:30:39,900 --> 00:30:44,020
+شو تعمل؟ تعمل adapt policies إنها تزود الـ
+
+404
+00:30:44,020 --> 00:30:46,100
+aggregate demand by maybe increasing the
+
+405
+00:30:46,100 --> 00:30:49,300
+government spending صح؟ أو يزودوا الـ money supply
+
+406
+00:30:49,300 --> 00:30:53,740
+صح؟ طيب أو اللي هم إيجوا يعملوا decreasing للـ
+
+407
+00:30:53,740 --> 00:30:57,920
+aggregate supply وبالتالي وين بنروح؟ بنجهان أو
+
+408
+00:30:57,920 --> 00:31:04,320
+بنجهان الـ price بتطلع صح؟ عشان يصير يسار يزيد الـ
+
+409
+00:31:04,320 --> 00:31:08,960
+wages يزيد التكليف الإنتاج؟ أه ممكن طيب، I have
+
+410
+00:31:08,960 --> 00:31:13,140
+another question هلأ الـ increasing في أو الـ
+
+411
+00:31:13,140 --> 00:31:21,740
+decreasing في الـ aggregate supply هذا شو اسمه؟
+
+412
+00:31:21,740 --> 00:31:24,360
+الـ leftward shifting اللي صار في الـ aggregate
+
+413
+00:31:24,360 --> 00:31:30,380
+exactly it's called the cost push inflation صح؟
+
+414
+00:31:30,380 --> 00:31:35,700
+تطخم اللي جاي نتيجة زيادة التكليف طب هذا الـ cost
+
+415
+00:31:35,700 --> 00:31:42,660
+push inflation شو عمل في الـ economy؟ اه يا ياسر؟
+
+416
+00:31:42,660 --> 00:31:46,580
+شو عمل بالـ economy هذا؟ الـ cost push inflation شو
+
+417
+00:31:46,580 --> 00:31:52,920
+عمل؟ inflation صحيح وشو عمل في الـ why؟ decrease في
+
+418
+00:31:52,920 --> 00:31:59,200
+الـ why إذا شو عمل؟ عمل inflation with employment
+
+419
+00:31:59,200 --> 00:32:01,560
+اللي هو الـ recession أو استهاجة الـ inflation
+
+420
+00:32:03,500 --> 00:32:06,400
+Stagflation لأن شو عندي هنا recession with
+
+421
+00:32:06,400 --> 00:32:10,540
+inflation مرجاتي
+
+422
+00:32:10,540 --> 00:32:18,300
+جهاز تمام طيب طب إذا هذا الـ course push inflation
+
+423
+00:32:18,300 --> 00:32:24,160
+شو عمل؟ عمل Stagflation صح؟ طيب demand pull
+
+424
+00:32:24,160 --> 00:32:28,220
+inflation شو بيعمل؟ demand pull inflation
+
+425
+00:32:31,290 --> 00:32:35,630
+لحظة لحظة لحظة let's do an analysis الـ demand pull
+
+426
+00:32:35,630 --> 00:32:38,530
+inflation شو عمل؟ يعني عملنا زيادة في الـ aggregate
+
+427
+00:32:38,530 --> 00:32:43,330
+demand؟ واش
+
+428
+00:32:43,330 --> 00:32:47,390
+بيعمل في الـ unemployment؟ بيزود النتج وبالتالي
+
+429
+00:32:47,390 --> 00:32:53,200
+بيقلل الـ unemployment، صح؟ إذا مين أثره أفضل أو
+
+430
+00:32:53,200 --> 00:32:57,260
+قليلا أقل ضرر عليه كلمة الـ demand pull لأنه demand
+
+431
+00:32:57,260 --> 00:33:03,140
+pull inflation شو عمل؟ عمل inflation وحل مشكلة الـ
+
+432
+00:33:03,140 --> 00:33:06,640
+unemployment صح؟ اللي الـ cost push inflation
+
+433
+00:33:06,640 --> 00:33:13,040
+creates two problems inflation and recession which
+
+434
+00:33:13,040 --> 00:33:19,480
+is this stagflation صح؟ لها يكون شاطرين بتحليله
+
+435
+00:33:19,480 --> 00:33:23,650
+ما شاء الله طيب، لنذهب إلى هذا البرنامج، البرنامج
+
+436
+00:33:23,650 --> 00:33:31,470
+طيب، كما ترى، في هذا البرنامج، نحن لدينا الـ Short 
+
+437
+00:33:31,470 --> 00:33:34,390
+-Run Aggregate Supply Curve والـ Long-Run
+
+438
+00:33:34,390 --> 00:33:38,230
+Aggregate Supply Curve، مظبوط؟ أين هو الـ GDP
+
+439
+00:33:38,230 --> 00:33:45,650
+المقدس بدون الإنفلاش؟ الـ GDP المقدس هو وين تقاطع
+
+440
+00:33:45,650 --> 00:33:48,970
+الـ Long-Run Aggregate Supply، إذا وين بيكون؟ 700
+
+441
+00:33:50,880 --> 00:33:57,440
+صح؟ مظبوط ولا لأ؟ طيب لو فرضنا أنه suppose ان الـ
+
+442
+00:33:57,440 --> 00:34:01,040
+government use an expansion fiscal policy by
+
+443
+00:34:01,040 --> 00:34:03,480
+increasing the government spending راح مزودين الـ
+
+444
+00:34:03,480 --> 00:34:06,960
+government spending هلا suppose this is the
+
+445
+00:34:06,960 --> 00:34:10,640
+initial aggregate demand curve this is the
+
+446
+00:34:10,640 --> 00:34:15,500
+aggregate demand one شو اللي بصير في الـ aggregate
+
+447
+00:34:15,500 --> 00:34:17,700
+demand يعني لو روحنا عاملين expansion fiscal
+
+448
+00:34:17,700 --> 00:34:20,720
+policy increasing the government spending شو بيعمل
+
+449
+00:34:20,720 --> 00:34:37,780
+increasing من الـ aggregate demand شو
+
+450
+00:34:37,780 --> 00:34:37,880
+بيعمل increasing من الـ aggregate demand شو بيعمل
+
+451
+00:34:37,880 --> 00:34:37,920
+increasing من الـ aggregate demand شو بيعمل
+
+452
+00:34:37,920 --> 00:34:37,960
+increasing من الـ aggregate demand شو بيعمل
+
+453
+00:34:37,960 --> 00:34:38,300
+increasing من الـ aggregate demand شو بيعمل
+
+454
+00:34:38,300 --> 00:34:41,800
+increasing من الـ aggregate demand aggregate output
+
+455
+00:34:41,800 --> 00:34:46,000
+in the short run and the long run هلا شو اللي صار
+
+456
+00:34:46,000 --> 00:34:47,840
+الـ aggregate output في الأجل القصير وفي الأجل
+
+457
+00:34:47,840 --> 00:34:52,440
+الطويل هلا في الأجل القصير وين أجينا زادت y
+
+458
+00:34:52,440 --> 00:34:57,580
+increase from 700 ل 800 صح؟ إذا أجينا لوين؟ للنقطة
+
+459
+00:34:57,580 --> 00:35:03,080
+هاي بس في الأجل الطويل شو الوضع؟ ليش؟
+
+460
+00:35:11,860 --> 00:35:15,700
+أوكي لكن .. لكن ما هي الأسباب الرئيسية لإخراجها في
+
+461
+00:35:15,700 --> 00:35:20,720
+هذه الحالة؟ حسنا
+
+462
+00:35:20,720 --> 00:35:26,280
+دعونا نعود للتعليقات كما ترون هذا هو مستوى الأسعار
+
+463
+00:35:26,280 --> 00:35:31,980
+الأصلي P1 تمام؟ تغيير كلمة صحيح في مطاولة التطبيق
+
+464
+00:35:31,980 --> 00:35:36,800
+المجتمعي في مجلة قصيرة شو عمل؟ أعزز أسعار .. هذا هو
+
+465
+00:35:36,800 --> 00:35:46,210
+E1 إلى E2 السعر ارتفع من P1 إلى P2، صح؟ الارتفاع في
+
+466
+00:35:46,210 --> 00:35:52,030
+مستوى السعر يسبب في ماذا؟ الارتفاع، لذا دعونا
+
+467
+00:35:52,030 --> 00:35:57,370
+نتابع الاناليز هنا، وفي الحالة الأولى، عندما يرتفع
+
+468
+00:35:57,370 --> 00:36:01,030
+السعر الحكومي، هذا يسبب في ارتفاع المطالبة، وهو ما
+
+469
+00:36:01,030 --> 00:36:09,240
+يسبب في ارتفاع السعر، صح؟ إذا أزداد السعر، ستزاد
+
+470
+00:36:09,240 --> 00:36:12,960
+السعر، صح؟ اللي هي cost of production. So this
+
+471
+00:36:12,960 --> 00:36:17,220
+leads to increasing the wages. و ليش الـ wages زادت؟
+
+472
+00:36:17,220 --> 00:36:20,520
+لأنه لما الـ prices طلعت، صاروا العمال بيطالبوا
+
+473
+00:36:20,520 --> 00:36:25,060
+بدون أجور أعلى، غلاء المعيشة. So this leads to
+
+474
+00:36:25,060 --> 00:36:29,700
+increasing the cost of production, which leads to
+
+475
+00:36:29,700 --> 00:36:34,690
+a decreasing aggregate supply curve. أو تغيير
+
+476
+00:36:34,690 --> 00:36:35,910
+المساعدة المساعدة المساعدة المساعدة المساعدة
+
+477
+00:36:35,910 --> 00:36:40,350
+المساعدة المساعدة المساعدة المساعدة
+
+478
+00:36:40,350 --> 00:36:43,310
+المساعدة المساعدة المساعدة المساعدة المساعدة
+
+479
+00:36:43,310 --> 00:36:45,630
+المساعدة المساعدة المساعدة المساعدة المساعدة
+
+480
+00:36:45,630 --> 00:36:46,430
+المساعدة المساعدة المساعدة المساعدة المساعدة
+
+481
+00:36:46,430 --> 00:36:47,610
+المساعدة المساعدة المساعدة المساعدة المساعدة
+
+482
+00:36:47,610 --> 00:36:47,990
+المساعدة المساعدة المساعدة المساعدة المساعدة
+
+483
+00:36:47,990 --> 00:36:54,060
+المساعدة المساعدة المساعدة المساعدة المساهذه
+
+484
+00:36:54,060 --> 00:37:02,740
+النقطة E1 E2 E3 الـ E1 هي الـ GDP الممتلكة بدون
+
+485
+00:37:02,740 --> 00:37:12,420
+انفلاش E3 هي الـ GDP الممتلكة بدون انفلاش E2
+
+486
+00:37:12,420 --> 00:37:17,780
+هي الوصول المجلد أو الوصول الحقيقي في الـ short
+
+487
+00:37:17,780 --> 00:37:18,140
+run
+
+488
+00:37:22,200 --> 00:37:26,800
+أه الناتج الحقيقي في الأجل القصير هيه 800 هذا الـ
+
+489
+00:37:26,800 --> 00:37:33,640
+potential output is 700 billion dollars in the
+
+490
+00:37:33,640 --> 00:37:37,000
+long term إذا الـ potential GDP or potential
+
+491
+00:37:37,000 --> 00:37:40,860
+equilibrium output أنه هذا إيش هو الـ potential
+
+492
+00:37:40,860 --> 00:37:46,700
+GDP؟ هو الـ long run aggregate supply صح؟
+
+493
+00:37:48,130 --> 00:37:51,890
+هلا شباب شباب الـ potential GDP or potential Y
+
+494
+00:37:51,890 --> 00:37:56,530
+potential aggregate output شو هو؟ سواء with ..
+
+495
+00:37:56,530 --> 00:37:58,810
+without inflation or with inflation هو شو؟ عبارة
+
+496
+00:37:58,810 --> 00:38:03,010
+عن إيش؟ الـ long run aggregate supply curve مصبوط؟
+
+497
+00:38:03,010 --> 00:38:06,510
+هو الـ long run aggregate supply طيب how could we
+
+498
+00:38:06,510 --> 00:38:10,810
+increase the potential GDP؟
+
+499
+00:38:14,190 --> 00:38:20,130
+كيف يمكننا ان نزعج GDP المحتوى من 700 إلى 800؟
+
+500
+00:38:20,130 --> 00:38:26,290
+انزعج مصادر المال؟ انزعاج مصادر المال يدفع إلى
+
+501
+00:38:26,290 --> 00:38:29,890
+انزعاج مطالب المال. لذلك لدينا تدفع مستمر، ليس
+
+502
+00:38:29,890 --> 00:38:30,850
+كذلك.
+
+503
+00:38:33,850 --> 00:38:41,990
+مالو؟ اي مصادر المال؟الـ aggregate supply بالضبط،
+
+504
+00:38:41,990 --> 00:38:48,770
+لذلك لإزالة الـ GDP الممكن من 700 إلى 800 يجب أن
+
+505
+00:38:48,770 --> 00:38:54,070
+نزالة الـ aggregate supply الممكن من 700 إلى 800،
+
+506
+00:38:54,070 --> 00:38:59,610
+صح؟ مظبوط؟ طيب، دعنا نذهب إلى التدريسات، الـ
+
+507
+00:38:59,610 --> 00:39:03,310
+output الممكن أو الـ GDP الممكن في هذه الحالة،
+
+508
+00:39:03,310 --> 00:39:06,190
+طبعا انا اقنع الفيجور أن الـ GDP الممكن أو الـ
+
+509
+00:39:06,190 --> 00:39:09,970
+output الممكن هو 700 refer to the figure the level
+
+510
+00:39:09,970 --> 00:39:13,850
+of aggregate output that can be sustained in the
+
+511
+00:39:13,850 --> 00:39:17,590
+long run without inflation اناول potential output
+
+512
+00:39:17,590 --> 00:39:23,170
+اللي بتضالها في الـ long run ايه 700 تمام the level
+
+513
+00:39:23,170 --> 00:39:26,230
+of aggregate output can be sustained in the long
+
+514
+00:39:26,230 --> 00:39:32,370
+run without inflation is known is known as what الـ
+
+515
+00:39:32,370 --> 00:39:39,350
+ايه الـ potential output طيب when the space فراغ
+
+516
+00:39:39,350 --> 00:39:43,910
+increased then the potential GDP increased اللي هو
+
+517
+00:39:43,910 --> 00:39:46,870
+long run aggregate supply لما الـ long run
+
+518
+00:39:46,870 --> 00:39:50,150
+aggregate supply بزيد شو اللي بصيد؟ بنروح على
+
+519
+00:39:50,150 --> 00:39:54,810
+potential GDP جديد طيب الـ potential output is
+
+520
+00:39:54,810 --> 00:39:59,930
+equal to what؟ the long run aggregate supply from
+
+521
+00:39:59,930 --> 00:40:08,180
+A to M الـ leftward shifting of aggregate supply
+
+522
+00:40:08,180 --> 00:40:11,480
+curve عبارة عن إيش هذا؟ هذا الـ cost push inflation
+
+523
+00:40:11,480 --> 00:40:16,600
+cost push inflation occurs إذا إيش إنه aggregate
+
+524
+00:40:16,600 --> 00:40:25,980
+supply shift to the left طيب
+
+525
+00:40:25,980 --> 00:40:30,600
+for an economy to experience both recession and
+
+526
+00:40:30,600 --> 00:40:34,640
+inflation at the same time لما بيكون فينا inflation
+
+527
+00:40:34,640 --> 00:40:37,900
+مع recession في نفس الوجه تاني اللي هو الاستاج
+
+528
+00:40:37,900 --> 00:40:42,780
+افلاشن وبيجي نتيجة ايهش انه the leftward shifting
+
+529
+00:40:42,780 --> 00:40:51,380
+of the aggregate supply curve صحيح تمام طيب what
+
+530
+00:40:51,380 --> 00:40:54,780
+about
+
+531
+00:40:54,780 --> 00:41:00,140
+this figure this is the aggregate demand aggregate
+
+532
+00:41:00,140 --> 00:41:00,780
+supply
+
+533
+00:41:04,470 --> 00:41:08,910
+الانتساكتشن بين الانتساكتشن و الانتساكتشن هنا إذا
+
+534
+00:41:08,910 --> 00:41:11,350
+كانت الحكومة .. أو خلّيني أشوف شوية .. إذا كانت
+
+535
+00:41:11,350 --> 00:41:14,830
+الانتساكتشن في الانتساكتشن بين الانتساكتشن و
+
+536
+00:41:14,830 --> 00:41:15,970
+الانتساكتشن و الانتساكتشن في الانتساكتشن و
+
+537
+00:41:15,970 --> 00:41:16,650
+الانتساكتشن و الانتساكتشن في الانتساكتشن و
+
+538
+00:41:16,650 --> 00:41:20,230
+الانتساكتشن في الانتساكتشن و الانتساكتشن في
+
+539
+00:41:20,230 --> 00:41:25,120
+الانتساكتشن و الانتساكتشبدنا نزود الـ money supply
+
+540
+00:41:25,120 --> 00:41:27,780
+لأن زيادة الـ money supply شو بتعمل؟ بتعمل a
+
+541
+00:41:27,780 --> 00:41:29,720
+rightward shifting في الـ aggregate demand curve
+
+542
+00:41:29,720 --> 00:41:31,660
+from aggregate demand one to aggregate demand two
+
+543
+00:41:31,660 --> 00:41:34,160
+then why would increase and unemployment would
+
+544
+00:41:34,160 --> 00:41:37,440
+decline؟ أو it can increase the government
+
+545
+00:41:37,440 --> 00:41:42,300
+spending أو decrease the taxes because here the
+
+546
+00:41:42,300 --> 00:41:45,680
+fiscal policy and the monetary policy are
+
+547
+00:41:45,680 --> 00:41:47,760
+effective طب هنا
+
+548
+00:41:53,950 --> 00:41:59,850
+في هذه الحالة هنا
+
+549
+00:41:59,850 --> 00:42:08,410
+الـ GDP الممكن يكون ماذا؟ Y0 مظبوط؟ طيب إذا كانت
+
+550
+00:42:08,410 --> 00:42:13,070
+الحكومة استخدمت قياسية تجارب تجارب تجارب تجارب
+
+551
+00:42:13,070 --> 00:42:14,830
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+552
+00:42:14,830 --> 00:42:14,890
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+553
+00:42:14,890 --> 00:42:15,290
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+554
+00:42:15,290 --> 00:42:15,990
+تجارب تجارب تجارب تجارب تجارب تجارب تجارب تجارب
+
+555
+00:42:15,990 --> 00:42:16,630
+تجارب
+
+556
+00:42:24,930 --> 00:42:28,850
+The fun is on this case and the crazy .. خلاص
+
+557
+00:42:28,850 --> 00:42:29,670
+أعطيكم العافية 
diff --git a/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/x0Av-Gurjik_raw.json b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/x0Av-Gurjik_raw.json
new file mode 100644
index 0000000000000000000000000000000000000000..386ccbb3e1901b6d1adcd366a1c6b6b7d508c056
--- /dev/null
+++ b/PL9fwy3NUQKwa0xJxXjRDvrdD8YNk4mTNg/x0Av-Gurjik_raw.json
@@ -0,0 +1 @@
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الفائدة", "probability": 0.9638671875}, {"start": 156.17, "end": 156.35, "word": " من", "probability": 0.9775390625}, {"start": 156.35, "end": 156.75, "word": " R1", "probability": 0.97216796875}, {"start": 156.75, "end": 157.47, "word": " لR2", "probability": 0.8494466145833334}, {"start": 157.47, "end": 160.45, "word": " بيجلل", "probability": 0.86025390625}, {"start": 160.45, "end": 161.21, "word": " ال", "probability": 0.8583984375}, {"start": 161.21, "end": 161.69, "word": " quantity", "probability": 0.9677734375}, {"start": 161.69, "end": 162.01, "word": " of", "probability": 0.94287109375}, {"start": 162.01, "end": 162.23, "word": " money", "probability": 0.9609375}, {"start": 162.23, "end": 162.83, "word": " demanded", "probability": 0.9462890625}, {"start": 162.83, "end": 163.05, "word": " ما", "probability": 0.7314453125}, {"start": 163.05, "end": 163.49, "word": " بنحكيش", "probability": 0.91328125}, {"start": 163.49, "end": 163.57, "word": " في", "probability": 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"word": " بين", "probability": 0.85400390625}, {"start": 171.69, "end": 171.79, "word": " ال", "probability": 0.76318359375}, {"start": 171.79, "end": 172.03, "word": " quantity", "probability": 0.350830078125}, {"start": 172.03, "end": 172.19, "word": " of", "probability": 0.78515625}, {"start": 172.19, "end": 172.31, "word": " money", "probability": 0.97265625}, {"start": 172.31, "end": 172.73, "word": " demanded", "probability": 0.95849609375}, {"start": 172.73, "end": 173.17, "word": " هاي", "probability": 0.54150390625}, {"start": 173.17, "end": 173.49, "word": " أول", "probability": 0.88232421875}, {"start": 173.49, "end": 174.01, "word": " determinant", "probability": 0.875}, {"start": 174.01, "end": 174.93, "word": " لمين؟", "probability": 0.78076171875}, {"start": 174.93, "end": 175.09, "word": " ل", "probability": 0.9189453125}, {"start": 175.09, "end": 175.65, "word": " ال", "probability": 0.10406494140625}, {"start": 175.65, "end": 175.83, "word": " money", "probability": 0.9794921875}, {"start": 175.83, "end": 176.29, "word": " demand", "probability": 0.73828125}, {"start": 176.29, "end": 177.91, "word": " في", "probability": 0.61083984375}, {"start": 177.91, "end": 178.25, "word": " عنا", "probability": 0.53619384765625}, {"start": 178.25, "end": 179.37, "word": " قولنا", "probability": 0.6998697916666666}, {"start": 179.37, "end": 179.49, "word": " في", "probability": 0.8916015625}, {"start": 179.49, "end": 179.81, "word": " جزء", "probability": 0.7960611979166666}, {"start": 179.81, "end": 180.29, "word": " اتين", "probability": 0.7648111979166666}], "temperature": 1.0}, {"id": 8, "seek": 20777, "start": 181.13, "end": 207.77, "text": "بيأثروا او two variables بيأثروا على ال money demand اول شي اللي هو the volume of transactions قيمة المبادلات وزي ما حكينا انه قيمة the volume of transactions يعني سببه ان احنا بدنا نشتري tomatoes and the beer box of tomato the price beer box of tomato", "tokens": [3555, 1829, 10721, 49115, 14407, 1975, 2407, 732, 9102, 4724, 1829, 10721, 49115, 14407, 15844, 2423, 1460, 4733, 1975, 12610, 44049, 13672, 1829, 31439, 264, 5523, 295, 16856, 12174, 32640, 3660, 9673, 3555, 18513, 1211, 9307, 4032, 11622, 1829, 19446, 11331, 4117, 1829, 8315, 16472, 3224, 12174, 32640, 3660, 264, 5523, 295, 16856, 37495, 22653, 8608, 3555, 3555, 3224, 16472, 1975, 5016, 8315, 47525, 8315, 8717, 8592, 2655, 16572, 15135, 293, 264, 8795, 2424, 295, 9288, 264, 3218, 8795, 2424, 295, 9288], "avg_logprob": -0.2210090314767447, "compression_ratio": 1.6600985221674878, "no_speech_prob": 0.0, "words": [{"start": 181.13, "end": 181.79, "word": "بيأثروا", "probability": 0.7156982421875}, {"start": 181.79, "end": 181.99, "word": " او", "probability": 0.753662109375}, {"start": 181.99, "end": 182.43, "word": " two", "probability": 0.53955078125}, {"start": 182.43, "end": 182.99, "word": " variables", "probability": 0.92724609375}, {"start": 182.99, "end": 183.65, "word": " بيأثروا", "probability": 0.96904296875}, {"start": 183.65, "end": 183.97, "word": " على", "probability": 0.81982421875}, {"start": 183.97, "end": 184.71, "word": " ال", "probability": 0.87109375}, {"start": 184.71, "end": 184.87, "word": " money", "probability": 0.92431640625}, {"start": 184.87, "end": 185.33, "word": " demand", "probability": 0.94970703125}, {"start": 185.33, "end": 186.07, "word": " اول", "probability": 0.796875}, {"start": 186.07, "end": 186.29, "word": " شي", "probability": 0.52490234375}, {"start": 186.29, "end": 186.77, "word": " اللي", "probability": 0.839111328125}, {"start": 186.77, "end": 187.01, "word": " هو", "probability": 0.98779296875}, {"start": 187.01, "end": 187.29, "word": " the", "probability": 0.65283203125}, {"start": 187.29, "end": 187.79, "word": " volume", "probability": 0.9462890625}, {"start": 187.79, "end": 188.03, "word": " of", "probability": 0.98046875}, {"start": 188.03, "end": 188.81, "word": " transactions", "probability": 0.9208984375}, {"start": 188.81, "end": 189.87, "word": " قيمة", "probability": 0.9611002604166666}, {"start": 189.87, "end": 190.67, "word": " المبادلات", "probability": 0.99287109375}, {"start": 190.67, "end": 191.47, "word": " وزي", "probability": 0.8453776041666666}, {"start": 191.47, "end": 191.53, "word": " ما", "probability": 0.9775390625}, {"start": 191.53, "end": 191.97, "word": " حكينا", "probability": 0.9840087890625}, {"start": 191.97, "end": 192.69, "word": " انه", "probability": 0.6826171875}, {"start": 192.69, "end": 192.99, "word": " قيمة", "probability": 0.9482421875}, {"start": 192.99, "end": 193.35, "word": " the", "probability": 0.314697265625}, {"start": 193.35, "end": 193.67, "word": " volume", "probability": 0.89306640625}, {"start": 193.67, "end": 194.09, "word": " of", "probability": 0.96826171875}, {"start": 194.09, "end": 195.09, "word": " transactions", "probability": 0.87109375}, {"start": 195.09, "end": 196.19, "word": " يعني", "probability": 0.943359375}, {"start": 196.19, "end": 196.55, "word": " سببه", "probability": 0.7679443359375}, {"start": 196.55, "end": 196.67, "word": " ان", "probability": 0.82373046875}, {"start": 196.67, "end": 196.81, "word": " احنا", "probability": 0.9163411458333334}, {"start": 196.81, "end": 197.07, "word": " بدنا", "probability": 0.656982421875}, {"start": 197.07, "end": 197.47, "word": " نشتري", "probability": 0.9884033203125}, {"start": 197.47, "end": 198.69, "word": " tomatoes", "probability": 0.68310546875}, {"start": 198.69, "end": 200.09, "word": " and", "probability": 0.8369140625}, {"start": 200.09, "end": 200.75, "word": " the", "probability": 0.371826171875}, {"start": 200.75, "end": 201.41, "word": " beer", "probability": 0.21630859375}, {"start": 201.41, "end": 201.63, "word": " box", "probability": 0.67138671875}, {"start": 201.63, "end": 201.81, "word": " of", "probability": 0.9541015625}, {"start": 201.81, "end": 202.25, "word": " tomato", "probability": 0.638671875}, {"start": 202.25, "end": 202.79, "word": " the", "probability": 0.5732421875}, {"start": 202.79, "end": 203.23, "word": " price", "probability": 0.93115234375}, {"start": 203.23, "end": 204.73, "word": " beer", "probability": 0.4130859375}, {"start": 204.73, "end": 205.49, "word": " box", "probability": 0.880859375}, {"start": 205.49, "end": 207.19, "word": " of", "probability": 0.97119140625}, {"start": 207.19, "end": 207.77, "word": " tomato", "probability": 0.96435546875}], "temperature": 1.0}, {"id": 9, "seek": 23759, "start": 212.13, "end": 237.59, "text": "equals 15 shekels سعر البكسيه تبعت البندوره 15 shekels and you would like to buy two boxes so the quantity demanded to equals two boxes قداش قيمة المبادلة كلها قيمة المعاملة اللي بدك تشتريها 30 shekels because so the volume", "tokens": [12816, 1124, 2119, 750, 7124, 82, 8608, 3615, 2288, 29739, 4117, 3794, 1829, 3224, 6055, 3555, 34268, 29739, 41260, 13063, 3224, 2119, 750, 7124, 82, 293, 291, 576, 411, 281, 2256, 732, 9002, 370, 264, 11275, 28276, 281, 6915, 732, 9002, 12174, 3215, 33599, 12174, 32640, 3660, 9673, 3555, 18513, 37977, 28242, 11296, 12174, 32640, 3660, 9673, 3615, 10943, 37977, 13672, 1829, 47525, 4117, 6055, 8592, 2655, 16572, 11296, 2217, 750, 7124, 82, 570, 370, 264, 5523], "avg_logprob": -0.2598157116235831, "compression_ratio": 1.5077720207253886, "no_speech_prob": 0.0, "words": [{"start": 212.12999999999997, "end": 213.14999999999998, "word": "equals", "probability": 0.51202392578125}, {"start": 213.14999999999998, "end": 214.17, "word": " 15", "probability": 0.6533203125}, {"start": 214.17, "end": 216.61, "word": " shekels", "probability": 0.6118977864583334}, {"start": 216.61, "end": 217.75, "word": " سعر", "probability": 0.9308268229166666}, {"start": 217.75, "end": 218.37, "word": " البكسيه", "probability": 0.6145751953125}, {"start": 218.37, "end": 218.81, "word": " تبعت", "probability": 0.6722005208333334}, {"start": 218.81, "end": 219.39, "word": " البندوره", "probability": 0.8311767578125}, {"start": 219.39, "end": 219.95, "word": " 15", "probability": 0.76806640625}, {"start": 219.95, "end": 221.07, "word": " shekels", "probability": 0.584228515625}, {"start": 221.07, "end": 221.29, "word": " and", "probability": 0.4345703125}, {"start": 221.29, "end": 221.47, "word": " you", "probability": 0.92724609375}, {"start": 221.47, "end": 221.67, "word": " would", "probability": 0.6318359375}, {"start": 221.67, "end": 221.89, "word": " like", "probability": 0.90283203125}, {"start": 221.89, "end": 222.07, "word": " to", "probability": 0.962890625}, {"start": 222.07, "end": 222.39, "word": " buy", "probability": 0.91943359375}, {"start": 222.39, "end": 223.55, "word": " two", "probability": 0.67724609375}, {"start": 223.55, "end": 224.27, "word": " boxes", "probability": 0.93017578125}, {"start": 224.27, "end": 224.93, "word": " so", "probability": 0.60986328125}, {"start": 224.93, "end": 225.13, "word": " the", "probability": 0.87158203125}, {"start": 225.13, "end": 225.65, "word": " quantity", "probability": 0.97412109375}, {"start": 225.65, "end": 226.73, "word": " demanded", "probability": 0.955078125}, {"start": 226.73, "end": 227.63, "word": " to", "probability": 0.62255859375}, {"start": 227.63, "end": 228.09, "word": " equals", "probability": 0.796875}, {"start": 228.09, "end": 228.37, "word": " two", "probability": 0.775390625}, {"start": 228.37, "end": 228.87, "word": " boxes", "probability": 0.9208984375}, {"start": 228.87, "end": 231.25, "word": " قداش", "probability": 0.6107584635416666}, {"start": 231.25, "end": 231.63, "word": " قيمة", "probability": 0.97998046875}, {"start": 231.63, "end": 232.15, "word": " المبادلة", "probability": 0.8902587890625}, {"start": 232.15, "end": 232.55, "word": " كلها", "probability": 0.98828125}, {"start": 232.55, "end": 233.05, "word": " قيمة", "probability": 0.9490559895833334}, {"start": 233.05, "end": 233.51, "word": " المعاملة", "probability": 0.96240234375}, {"start": 233.51, "end": 233.61, "word": " اللي", "probability": 0.753173828125}, {"start": 233.61, "end": 233.77, "word": " بدك", "probability": 0.931396484375}, {"start": 233.77, "end": 234.29, "word": " تشتريها", "probability": 0.98876953125}, {"start": 234.29, "end": 235.63, "word": " 30", "probability": 0.61328125}, {"start": 235.63, "end": 236.19, "word": " shekels", "probability": 0.9075520833333334}, {"start": 236.19, "end": 236.41, "word": " because", "probability": 0.86279296875}, {"start": 236.41, "end": 236.95, "word": " so", "probability": 0.6103515625}, {"start": 236.95, "end": 237.13, "word": " the", "probability": 0.916015625}, {"start": 237.13, "end": 237.59, "word": " volume", "probability": 0.94677734375}], "temperature": 1.0}, {"id": 10, "seek": 25927, "start": 240.55, "end": 259.27, "text": "of transaction equals to price times quantity مايساوي كدهش عند ال price خمس عشر شكل times ال quantity demanded اتنين equals thirty shekels", "tokens": [2670, 14425, 6915, 281, 3218, 1413, 11275, 19446, 1829, 3794, 995, 45865, 9122, 3215, 3224, 8592, 43242, 2423, 3218, 16490, 2304, 3794, 6225, 46309, 13412, 28820, 1413, 2423, 11275, 28276, 1975, 2655, 1863, 9957, 6915, 11790, 750, 7124, 82], "avg_logprob": -0.48320312798023224, "compression_ratio": 1.2592592592592593, "no_speech_prob": 0.0, "words": [{"start": 240.55, "end": 240.83, "word": "of", "probability": 0.1778564453125}, {"start": 240.83, "end": 241.67, "word": " transaction", "probability": 0.673828125}, {"start": 241.67, "end": 245.49, "word": " equals", "probability": 0.5283203125}, {"start": 245.49, "end": 245.73, "word": " to", "probability": 0.276611328125}, {"start": 245.73, "end": 246.27, "word": " price", "probability": 0.71728515625}, {"start": 246.27, "end": 246.87, "word": " times", "probability": 0.5302734375}, {"start": 246.87, "end": 247.55, "word": " quantity", "probability": 0.91552734375}, {"start": 247.55, "end": 249.11, "word": " مايساوي", "probability": 0.66876220703125}, {"start": 249.11, "end": 250.17, "word": " كدهش", "probability": 0.540771484375}, {"start": 250.17, "end": 250.29, "word": " عند", "probability": 0.9306640625}, {"start": 250.29, "end": 250.43, "word": " ال", "probability": 0.88623046875}, {"start": 250.43, "end": 250.79, "word": " price", "probability": 0.91552734375}, {"start": 250.79, "end": 251.49, "word": " خمس", "probability": 0.777587890625}, {"start": 251.49, "end": 251.81, "word": " عشر", "probability": 0.5745849609375}, {"start": 251.81, "end": 252.17, "word": " شكل", "probability": 0.748046875}, {"start": 252.17, "end": 253.83, "word": " times", "probability": 0.62451171875}, {"start": 253.83, "end": 254.31, "word": " ال", "probability": 0.2279052734375}, {"start": 254.31, "end": 254.75, "word": " quantity", "probability": 0.9248046875}, {"start": 254.75, "end": 255.39, "word": " demanded", "probability": 0.966796875}, {"start": 255.39, "end": 256.41, "word": " اتنين", "probability": 0.9378662109375}, {"start": 256.41, "end": 257.83, "word": " equals", "probability": 0.77490234375}, {"start": 257.83, "end": 258.51, "word": " thirty", "probability": 0.5546875}, {"start": 258.51, "end": 259.27, "word": " shekels", "probability": 0.763671875}], "temperature": 1.0}, {"id": 11, "seek": 28732, "start": 260.4, "end": 287.32, "text": "طيب هذا ايش ال volume of transaction suppose ان ال price طلعت يعني صرت انت ال pair price of tomato بدل ما هو 15 حق ال books صار 20 شكل this means ان انت محتاج more money to buy the same quantity صح؟ عشان تشتري نفس الكميات محتاج more money صح؟ so suppose", "tokens": [9566, 1829, 3555, 23758, 1975, 1829, 8592, 2423, 5523, 295, 14425, 7297, 16472, 2423, 3218, 23032, 1211, 34268, 37495, 22653, 20328, 43500, 16472, 2655, 2423, 6119, 3218, 295, 9288, 47525, 1211, 19446, 31439, 2119, 11331, 4587, 2423, 3642, 20328, 9640, 945, 13412, 28820, 341, 1355, 16472, 16472, 2655, 3714, 33753, 26108, 544, 1460, 281, 2256, 264, 912, 11275, 20328, 5016, 22807, 6225, 8592, 7649, 6055, 8592, 2655, 16572, 8717, 36178, 33251, 2304, 1829, 9307, 3714, 33753, 26108, 544, 1460, 20328, 5016, 22807, 370, 7297], "avg_logprob": -0.23860294398139506, "compression_ratio": 1.502202643171806, "no_speech_prob": 0.0, "words": [{"start": 260.4, "end": 261.2, "word": "طيب", "probability": 0.9314778645833334}, {"start": 261.2, "end": 261.7, "word": " هذا", "probability": 0.499267578125}, {"start": 261.7, "end": 262.0, "word": " ايش", "probability": 0.6263020833333334}, {"start": 262.0, "end": 262.16, "word": " ال", "probability": 0.560546875}, {"start": 262.16, "end": 262.52, "word": " volume", "probability": 0.9375}, {"start": 262.52, "end": 262.7, "word": " of", "probability": 0.9599609375}, {"start": 262.7, "end": 263.3, "word": " transaction", "probability": 0.461181640625}, {"start": 263.3, "end": 263.86, "word": " suppose", "probability": 0.29443359375}, {"start": 263.86, "end": 264.1, "word": " ان", "probability": 0.8076171875}, {"start": 264.1, "end": 264.22, "word": " ال", "probability": 0.560546875}, {"start": 264.22, "end": 264.64, "word": " price", "probability": 0.953125}, {"start": 264.64, 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"probability": 0.91845703125}, {"start": 638.67, "end": 638.93, "word": " money", "probability": 0.9619140625}, {"start": 638.93, "end": 639.45, "word": " demand", "probability": 0.94189453125}, {"start": 639.45, "end": 639.63, "word": " would", "probability": 0.8515625}, {"start": 639.63, "end": 640.07, "word": " increase", "probability": 0.90380859375}], "temperature": 1.0}, {"id": 26, "seek": 65396, "start": 640.74, "end": 653.96, "text": "الزيادة في ال money demand هو اللي بتودي اللي بتعملي rightward shifting في ال money demand curve سببوز إنه هي ال equilibrium هي ال money demand 1 و هي ال money supply و الملتقين عند A1 هذا في عند ال equilibrium interest rate صح؟", "tokens": [6027, 11622, 1829, 18513, 3660, 8978, 2423, 1460, 4733, 31439, 13672, 1829, 39894, 2407, 16254, 13672, 1829, 39894, 25957, 20292, 558, 1007, 17573, 8978, 2423, 1460, 4733, 7605, 8608, 3555, 3555, 2407, 11622, 36145, 3224, 39896, 2423, 15625, 39896, 2423, 1460, 4733, 502, 4032, 39896, 2423, 1460, 5847, 4032, 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في أسعار الفائضة increasing في ال interest rate ناخد تأثير لـ quantity يعني suppose انه in this example the price for a box of tomato is 15 shekels", "tokens": [6027, 9640, 2655, 5172, 45761, 6024, 110, 1829, 18513, 3660, 8978, 2423, 39184, 1460, 4733, 6225, 42213, 558, 1007, 17573, 24976, 39184, 1460, 4733, 7605, 46599, 6027, 2655, 6027, 1829, 8978, 3224, 294, 264, 777, 15625, 935, 4032, 3215, 2655, 8717, 45367, 2407, 9957, 1975, 43500, 5172, 45761, 8978, 5551, 3794, 3615, 9640, 27188, 16373, 11242, 3660, 5662, 8978, 2423, 1179, 3314, 8717, 47283, 3215, 6055, 10721, 12984, 13546, 5296, 39184, 11275, 37495, 22653, 7297, 16472, 3224, 294, 341, 1365, 264, 3218, 337, 257, 2424, 295, 9288, 307, 2119, 750, 7124, 82], "avg_logprob": -0.25537635690422467, "compression_ratio": 1.4708171206225682, "no_speech_prob": 0.0, "words": [{"start": 654.8, "end": 655.54, "word": "الارتفاع", "probability": 0.9453125}, {"start": 655.54, "end": 655.92, "word": " الزيادة", "probability": 0.89697265625}, 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"start": 681.14, "end": 704.32, "text": "و الكميات كنا بنشتريها two boxes هلقيت بده افترض انه انا I want more او I want to increase the quant of purchase of tomato يعني انا بده اشتري كميات اكبر من ال tomato and the prices remain constant يعني انا الأسعار ثابتة تباعت ليه و there is no change in the prices of tomato و بده اشتري كميات اكبر يعني suppose انه ال price هيك", "tokens": [2407, 33251, 2304, 1829, 9307, 9122, 8315, 44945, 8592, 2655, 16572, 11296, 732, 9002, 8032, 1211, 4587, 36081, 47525, 3224, 1975, 5172, 2655, 43042, 16472, 3224, 1975, 8315, 286, 528, 544, 1975, 2407, 286, 528, 281, 3488, 264, 4426, 295, 8110, 295, 9288, 37495, 22653, 1975, 8315, 47525, 3224, 1975, 8592, 2655, 16572, 9122, 2304, 1829, 9307, 1975, 4117, 26890, 9154, 2423, 9288, 293, 264, 7901, 6222, 5754, 37495, 22653, 1975, 8315, 16247, 3794, 3615, 9640, 38637, 16758, 2655, 3660, 6055, 3555, 995, 34268, 32239, 3224, 4032, 456, 307, 572, 1319, 294, 264, 7901, 295, 9288, 4032, 47525, 3224, 1975, 8592, 2655, 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"probability": 0.90966796875}, {"start": 766.59, "end": 767.05, "word": " او", "probability": 0.87646484375}, {"start": 767.05, "end": 767.15, "word": " في", "probability": 0.9560546875}, {"start": 767.15, "end": 767.83, "word": " الكميات", "probability": 0.9073486328125}, {"start": 767.83, "end": 768.07, "word": " or", "probability": 0.87353515625}, {"start": 768.07, "end": 768.57, "word": " both", "probability": 0.9208984375}, {"start": 768.57, "end": 769.43, "word": " means", "probability": 0.873046875}, {"start": 769.43, "end": 769.57, "word": " ان", "probability": 0.90869140625}, {"start": 769.57, "end": 769.69, "word": " ال", "probability": 0.79833984375}, {"start": 769.69, "end": 770.01, "word": " volume", "probability": 0.986328125}, {"start": 770.01, "end": 770.75, "word": " transaction", "probability": 0.8857421875}, {"start": 770.75, "end": 771.35, "word": " زاد", "probability": 0.966796875}], "temperature": 1.0}, {"id": 32, "seek": 80119, "start": 771.89, "end": 801.19, "text": "وبالتالي I need more money to buy the .. او to meet the new volume of a transaction صح؟ إذا زيادت الكميات اللي بدنا نشتريها ودتنا علوين إنه ال volume of transaction زاد صح؟ وبالتالي I need more money to buy وبالتالي ال money demand شو بيصير فيه؟", "tokens": [37746, 6027, 2655, 6027, 1829, 286, 643, 544, 1460, 281, 2256, 264, 4386, 1975, 2407, 281, 1677, 264, 777, 5523, 295, 257, 14425, 20328, 5016, 22807, 11933, 15730, 30767, 1829, 18513, 2655, 33251, 2304, 1829, 9307, 13672, 1829, 47525, 8315, 8717, 8592, 2655, 16572, 11296, 4032, 3215, 2655, 8315, 11203, 2407, 9957, 36145, 3224, 2423, 5523, 295, 14425, 30767, 18513, 20328, 5016, 22807, 46599, 6027, 2655, 6027, 1829, 286, 643, 544, 1460, 281, 2256, 46599, 6027, 2655, 6027, 1829, 2423, 1460, 4733, 13412, 2407, 4724, 1829, 9381, 13546, 8978, 3224, 22807], "avg_logprob": -0.20431385480839273, "compression_ratio": 1.715736040609137, "no_speech_prob": 0.0, "words": [{"start": 771.89, "end": 772.41, "word": "وبالتالي", 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"word": " ودتنا", "probability": 0.898681640625}, {"start": 784.33, "end": 784.77, "word": " علوين", "probability": 0.642333984375}, {"start": 784.77, "end": 785.53, "word": " إنه", "probability": 0.5745849609375}, {"start": 785.53, "end": 785.73, "word": " ال", "probability": 0.8935546875}, {"start": 785.73, "end": 786.09, "word": " volume", "probability": 0.93994140625}, {"start": 786.09, "end": 786.25, "word": " of", "probability": 0.97607421875}, {"start": 786.25, "end": 786.95, "word": " transaction", "probability": 0.419921875}, {"start": 786.95, "end": 787.39, "word": " زاد", "probability": 0.8291015625}, {"start": 787.39, "end": 789.55, "word": " صح؟", "probability": 0.8486328125}, {"start": 789.55, "end": 790.21, "word": " وبالتالي", "probability": 0.91142578125}, {"start": 790.21, "end": 790.73, "word": " I", "probability": 0.9296875}, {"start": 790.73, "end": 791.17, "word": " need", "probability": 0.95556640625}, {"start": 791.17, "end": 792.99, "word": " more", "probability": 0.9541015625}, {"start": 792.99, "end": 793.41, "word": " money", "probability": 0.9521484375}, {"start": 793.41, "end": 798.21, "word": " to", "probability": 0.921875}, {"start": 798.21, "end": 798.49, "word": " buy", "probability": 0.92724609375}, {"start": 798.49, "end": 799.29, "word": " وبالتالي", "probability": 0.93984375}, {"start": 799.29, "end": 799.43, "word": " ال", "probability": 0.78662109375}, {"start": 799.43, "end": 799.57, "word": " money", "probability": 0.9619140625}, {"start": 799.57, "end": 800.07, "word": " demand", "probability": 0.9736328125}, {"start": 800.07, "end": 800.45, "word": " شو", "probability": 0.89697265625}, {"start": 800.45, "end": 800.75, "word": " بيصير", "probability": 0.9583740234375}, {"start": 800.75, "end": 801.19, "word": " فيه؟", "probability": 0.9786783854166666}], "temperature": 1.0}, {"id": 33, "seek": 82742, "start": 802.22, "end": 827.42, "text": "with increase اذا في عندي rightward shifting of the money demand curve صح؟ اذا هذا بوديني على وين؟ rightward shifting of the money demand curve طب لما ينتقل ال money demand curve لليمين معنى الكلام انه ال interest rate هيزيد صح؟ صعب؟ طيب", "tokens": [11820, 3488, 1975, 15730, 8978, 18871, 16254, 558, 1007, 17573, 295, 264, 1460, 4733, 7605, 20328, 5016, 22807, 1975, 15730, 23758, 4724, 23328, 9957, 1829, 15844, 4032, 9957, 22807, 558, 1007, 17573, 295, 264, 1460, 4733, 7605, 23032, 3555, 5296, 15042, 7251, 29399, 4587, 1211, 2423, 1460, 4733, 7605, 5296, 20292, 2304, 9957, 20449, 1863, 7578, 2423, 28820, 10943, 16472, 3224, 2423, 1179, 3314, 39896, 11622, 25708, 20328, 5016, 22807, 20328, 3615, 3555, 22807, 23032, 1829, 3555], "avg_logprob": -0.2301682724784582, "compression_ratio": 1.6719576719576719, "no_speech_prob": 5.960464477539063e-08, "words": [{"start": 802.22, "end": 802.44, "word": "with", "probability": 0.2159423828125}, {"start": 802.44, "end": 802.96, "word": " increase", "probability": 0.86376953125}, {"start": 802.96, "end": 804.3, "word": " اذا", "probability": 0.56707763671875}, {"start": 804.3, "end": 804.48, "word": " في", "probability": 0.8037109375}, {"start": 804.48, "end": 804.88, "word": " عندي", "probability": 0.6966552734375}, {"start": 804.88, "end": 805.86, "word": " rightward", "probability": 0.763671875}, {"start": 805.86, "end": 806.3, "word": " shifting", "probability": 0.86865234375}, {"start": 806.3, "end": 806.76, "word": " of", "probability": 0.93701171875}, {"start": 806.76, "end": 806.88, "word": " the", "probability": 0.490478515625}, {"start": 806.88, "end": 807.04, "word": " money", "probability": 0.95751953125}, {"start": 807.04, "end": 807.46, "word": " demand", "probability": 0.9443359375}, {"start": 807.46, "end": 807.8, "word": " curve", "probability": 0.9716796875}, {"start": 807.8, "end": 808.58, "word": " صح؟", "probability": 0.721923828125}, {"start": 808.58, "end": 808.86, "word": " اذا", "probability": 0.889892578125}, {"start": 808.86, "end": 809.08, "word": " هذا", "probability": 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816.7, "end": 817.1, "word": " ينتقل", "probability": 0.8541259765625}, {"start": 817.1, "end": 817.18, "word": " ال", "probability": 0.48779296875}, {"start": 817.18, "end": 817.3, "word": " money", "probability": 0.958984375}, {"start": 817.3, "end": 817.64, "word": " demand", "probability": 0.95263671875}, {"start": 817.64, "end": 818.04, "word": " curve", "probability": 0.98095703125}, {"start": 818.04, "end": 819.24, "word": " لليمين", "probability": 0.8489990234375}, {"start": 819.24, "end": 820.1, "word": " معنى", "probability": 0.94775390625}, {"start": 820.1, "end": 820.46, "word": " الكلام", "probability": 0.9622395833333334}, {"start": 820.46, "end": 821.0, "word": " انه", "probability": 0.708251953125}, {"start": 821.0, "end": 821.26, "word": " ال", "probability": 0.9677734375}, {"start": 821.26, "end": 821.6, "word": " interest", "probability": 0.916015625}, {"start": 821.6, "end": 821.98, "word": " rate", "probability": 0.97607421875}, {"start": 821.98, "end": 822.56, "word": " هيزيد", "probability": 0.8522135416666666}, {"start": 822.56, "end": 825.84, "word": " صح؟", "probability": 0.89892578125}, {"start": 825.84, "end": 826.78, "word": " صعب؟", "probability": 0.8955078125}, {"start": 826.78, "end": 827.42, "word": " طيب", "probability": 0.9532877604166666}], "temperature": 1.0}, {"id": 34, "seek": 85629, "start": 828.95, "end": 856.29, "text": "I have a question مين بيطلب مصاري اكتر؟ الغني ولا الفقير؟ الغني الغني، اذا زيادة ال income بتزود ال money demand لأنه الغني بدي اشتري كميات اكبر يعني الفقير بيقولك ماشي احنا جاية بوكسة منذورة، ماشي الحال بنتسلق حالنا طول الشهرين مثلا او الشهر او الكذا لكن الغني بيجيب كميات أطل اكتر وبالتالي هذا بيودنا على وين؟ انه ال income لما بيزيد or when income increased زيادة ال income", "tokens": [40, 362, 257, 1168, 3714, 9957, 4724, 1829, 9566, 46152, 3714, 9381, 9640, 1829, 1975, 4117, 2655, 2288, 22807, 6024, 118, 22653, 49429, 27188, 4587, 13546, 22807, 6024, 118, 22653, 2423, 17082, 22653, 12399, 1975, 15730, 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quant of money التوازني هان تمام؟ suppose انه اجى ال central bank و قالك انا بدي ازود عرض النقد to increase ال money supply اي زيادة في العرض النقد بتعمل ال money supply curve لليمين shift to the right وبالتالي هنيجي وين؟ هان هيك", "tokens": [2407, 9957, 16712, 2407, 31377, 1863, 16247, 3794, 32277, 1829, 22807, 8032, 1829, 2407, 412, 462, 16, 43242, 2423, 1179, 3314, 307, 497, 16, 4032, 2423, 4426, 295, 1460, 16712, 2407, 31377, 22653, 8032, 7649, 6055, 15042, 2304, 22807, 7297, 16472, 3224, 1975, 7435, 7578, 2423, 5777, 3765, 4032, 50239, 4117, 1975, 8315, 4724, 16254, 1975, 11622, 23328, 6225, 43042, 28239, 28543, 281, 3488, 2423, 1460, 5847, 1975, 1829, 30767, 1829, 18513, 3660, 8978, 18863, 43042, 28239, 28543, 39894, 25957, 1211, 2423, 1460, 5847, 7605, 5296, 20292, 2304, 9957, 5513, 281, 264, 558, 46599, 6027, 2655, 6027, 1829, 8032, 22653, 7435, 1829, 4032, 9957, 22807, 8032, 7649, 39896, 4117], "avg_logprob": -0.2609374913302335, "compression_ratio": 1.6159695817490494, 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"probability": 0.78369140625}, {"start": 1260.12, "end": 1260.28, "word": " money", "probability": 0.96923828125}, {"start": 1260.28, "end": 1260.72, "word": " supply", "probability": 0.982421875}, {"start": 1260.72, "end": 1261.62, "word": " اي", "probability": 0.82666015625}, {"start": 1261.62, "end": 1262.14, "word": " زيادة", "probability": 0.9842529296875}, {"start": 1262.14, "end": 1262.4, "word": " في", "probability": 0.87548828125}, {"start": 1262.4, "end": 1263.2, "word": " العرض", "probability": 0.7420654296875}, {"start": 1263.2, "end": 1263.54, "word": " النقد", "probability": 0.969970703125}, {"start": 1263.54, "end": 1264.04, "word": " بتعمل", "probability": 0.9708658854166666}, {"start": 1264.04, "end": 1264.66, "word": " ال", "probability": 0.94189453125}, {"start": 1264.66, "end": 1264.86, "word": " money", "probability": 0.9677734375}, {"start": 1264.86, "end": 1265.2, "word": " supply", "probability": 0.97412109375}, {"start": 1265.2, "end": 1265.52, "word": " curve", "probability": 0.96728515625}, {"start": 1265.52, "end": 1266.02, "word": " لليمين", "probability": 0.8475341796875}, {"start": 1266.02, "end": 1267.02, "word": " shift", "probability": 0.77197265625}, {"start": 1267.02, "end": 1267.5, "word": " to", "probability": 0.97900390625}, {"start": 1267.5, "end": 1267.64, "word": " the", "probability": 0.93701171875}, {"start": 1267.64, "end": 1267.92, "word": " right", "probability": 0.9326171875}, {"start": 1267.92, "end": 1268.58, "word": " وبالتالي", "probability": 0.88037109375}, {"start": 1268.58, "end": 1269.02, "word": " هنيجي", "probability": 0.861083984375}, {"start": 1269.02, "end": 1269.72, "word": " وين؟", "probability": 0.8416341145833334}, {"start": 1269.72, "end": 1269.98, "word": " هان", "probability": 0.962890625}, {"start": 1269.98, "end": 1270.3, "word": " هيك", "probability": 0.808349609375}], "temperature": 1.0}, {"id": 52, "seek": 129618, "start": 1272.76, "end": 1296.18, "text": "طبعا و ال amount of demand suppose انه constant اجينا لوين ل money supply 2 و اين ال equilibrium صار قال اذا اجينا على A2 و هنا كان في عندي انزول في ال interest rate ل R2 و ال quant of money راحت زادت اذا الزيادة في ال money supply شو عملت؟", "tokens": [9566, 3555, 3615, 995, 4032, 2423, 2372, 295, 4733, 7297, 16472, 3224, 5754, 1975, 7435, 1829, 8315, 45164, 9957, 5296, 1460, 5847, 568, 4032, 1975, 9957, 2423, 15625, 20328, 9640, 50239, 1975, 15730, 1975, 7435, 1829, 8315, 15844, 316, 17, 4032, 34105, 25961, 8978, 18871, 16254, 16472, 11622, 12610, 8978, 2423, 1179, 3314, 5296, 497, 17, 4032, 2423, 4426, 295, 1460, 12602, 39319, 2655, 30767, 18513, 2655, 1975, 15730, 6024, 110, 1829, 18513, 3660, 8978, 2423, 1460, 5847, 13412, 2407, 6225, 42213, 2655, 22807], "avg_logprob": -0.2715073627584121, "compression_ratio": 1.572093023255814, "no_speech_prob": 0.0, "words": [{"start": 1272.76, "end": 1273.18, "word": "طبعا", "probability": 0.849853515625}, {"start": 1273.18, "end": 1273.3, "word": " و", "probability": 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اعمل declining لل required reserve ratio نسبة الاحتياطات قالوني جالك بدل ما بدي عشرين في المية تعطوني كبنوك خليه لعشرة في المية و بعدين خلوا معاكم مصاري صح؟ اذا هذا وين مداني؟ على انه increasing في ال money supply و بعدين ال money supply curve وين راح؟ ده right", "tokens": [11149, 4357, 278, 264, 4739, 17824, 8509, 1975, 15730, 13412, 2407, 16247, 3215, 2407, 9307, 13672, 1829, 44713, 9778, 40448, 2655, 11296, 1975, 2407, 44713, 9778, 40448, 11296, 2423, 5777, 3765, 6225, 8592, 7649, 7251, 11622, 23328, 2423, 1460, 5847, 1975, 15042, 16472, 3224, 1975, 25957, 1211, 34298, 24976, 4739, 17824, 8509, 8717, 35457, 3660, 2423, 39319, 31371, 41193, 9307, 12174, 6027, 11536, 1829, 10874, 6027, 4117, 47525, 1211, 19446, 4724, 16254, 6225, 46309, 9957, 8978, 9673, 10632, 37279, 9566, 11536, 1829, 9122, 3555, 1863, 2407, 4117, 16490, 20292, 3224, 5296, 3615, 8592, 25720, 8978, 9673, 10632, 4032, 39182, 9957, 16490, 1211, 14407, 20449, 995, 24793, 3714, 9381, 9640, 1829, 20328, 5016, 22807, 1975, 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"probability": 0.93994140625}, {"start": 1457.69, "end": 1458.17, "word": " او", "probability": 0.914794921875}, {"start": 1458.17, "end": 1459.33, "word": " يزود", "probability": 0.9754231770833334}, {"start": 1459.33, "end": 1459.47, "word": " ال", "probability": 0.89453125}, {"start": 1459.47, "end": 1459.73, "word": " discount", "probability": 0.970703125}, {"start": 1459.73, "end": 1460.27, "word": " rate", "probability": 0.9697265625}, {"start": 1460.27, "end": 1460.65, "word": " او", "probability": 0.959228515625}, {"start": 1460.65, "end": 1461.23, "word": " يعمل", "probability": 0.9812825520833334}, {"start": 1461.23, "end": 1461.71, "word": " selling", "probability": 0.78466796875}, {"start": 1461.71, "end": 1462.01, "word": " لل", "probability": 0.5888671875}, {"start": 1462.01, "end": 1462.35, "word": " bonds", "probability": 0.55029296875}], "temperature": 1.0}, {"id": 59, "seek": 148913, "start": 1467.17, "end": 1489.13, "text": "صعب؟ طيب suppose انه ال income declined خلينا ناخد التأثير على ال money demand يعني احنا قولنا فيه ال prices بتأثر على ال money demand curve و ال quantity purchased اللي هو اللي له علاقة بال volume transaction", "tokens": [9381, 3615, 3555, 22807, 23032, 1829, 3555, 7297, 16472, 3224, 2423, 5742, 29213, 16490, 20292, 8315, 8717, 47283, 3215, 16712, 10721, 12984, 13546, 15844, 2423, 1460, 4733, 37495, 22653, 1975, 5016, 8315, 12174, 12610, 8315, 8978, 3224, 2423, 7901, 39894, 10721, 49115, 15844, 2423, 1460, 4733, 7605, 4032, 2423, 11275, 14734, 13672, 1829, 31439, 13672, 1829, 46740, 11203, 995, 28671, 20666, 5523, 14425], "avg_logprob": -0.20458984072320163, "compression_ratio": 1.5103092783505154, "no_speech_prob": 0.0, "words": [{"start": 1467.17, "end": 1468.01, "word": "صعب؟", "probability": 0.7109375}, {"start": 1468.01, "end": 1468.85, "word": " طيب", "probability": 0.7470703125}, {"start": 1468.85, "end": 1470.33, "word": " suppose", "probability": 0.3095703125}, {"start": 1470.33, "end": 1472.05, "word": " انه", 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احنا", "probability": 0.9210611979166666}, {"start": 1481.23, "end": 1481.47, "word": " قولنا", "probability": 0.8806966145833334}, {"start": 1481.47, "end": 1481.67, "word": " فيه", "probability": 0.87548828125}, {"start": 1481.67, "end": 1481.77, "word": " ال", "probability": 0.92333984375}, {"start": 1481.77, "end": 1482.13, "word": " prices", "probability": 0.7900390625}, {"start": 1482.13, "end": 1482.65, "word": " بتأثر", "probability": 0.86181640625}, {"start": 1482.65, "end": 1482.77, "word": " على", "probability": 0.8876953125}, {"start": 1482.77, "end": 1482.85, "word": " ال", "probability": 0.7705078125}, {"start": 1482.85, "end": 1482.97, "word": " money", "probability": 0.97265625}, {"start": 1482.97, "end": 1483.29, "word": " demand", "probability": 0.9521484375}, {"start": 1483.29, "end": 1483.59, "word": " curve", "probability": 0.96240234375}, {"start": 1483.59, "end": 1484.49, "word": " و", "probability": 0.7412109375}, {"start": 1484.49, "end": 1485.37, "word": " 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وفي نفس الوقت صار فيه اندزياد في ال money supply بدا نشوف where is the new interest rate تمام خلنا ناخد الجزء هذا اللي هو متعلق بال money demand اه بدا نعمل تغييرات في .. نروح على ال money demand وبعدين نعمل تغيير في ال both في التنين يعني suppose انه the original equilibrium interest rate كان هنا", "tokens": [11622, 18513, 4724, 28259, 8717, 8592, 38688, 6055, 10721, 12984, 13546, 3224, 15844, 2423, 1460, 4733, 4032, 41185, 8717, 36178, 2423, 30543, 2655, 20328, 9640, 8978, 3224, 16472, 3215, 11622, 1829, 18513, 8978, 2423, 1460, 5847, 4724, 28259, 8717, 8592, 38688, 689, 307, 264, 777, 1179, 3314, 46811, 10943, 16490, 1211, 8315, 8717, 47283, 3215, 25724, 11622, 38207, 23758, 13672, 1829, 31439, 44650, 30241, 4587, 20666, 1460, 4733, 1975, 3224, 4724, 28259, 8717, 25957, 1211, 6055, 17082, 1829, 13546, 9307, 8978, 4386, 8717, 32887, 5016, 15844, 2423, 1460, 4733, 46599, 22488, 9957, 8717, 25957, 1211, 6055, 17082, 1829, 13546, 8978, 2423, 1293, 8978, 16712, 1863, 9957, 37495, 22653, 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"probability": 0.86376953125}, {"start": 1514.19, "end": 1514.63, "word": " انه", "probability": 0.780517578125}, {"start": 1514.63, "end": 1515.01, "word": " the", "probability": 0.5908203125}, {"start": 1515.01, "end": 1515.67, "word": " original", "probability": 0.95263671875}, {"start": 1515.67, "end": 1518.23, "word": " equilibrium", "probability": 0.9794921875}, {"start": 1518.23, "end": 1519.01, "word": " interest", "probability": 0.9345703125}, {"start": 1519.01, "end": 1519.39, "word": " rate", "probability": 0.97802734375}, {"start": 1519.39, "end": 1519.69, "word": " كان", "probability": 0.99072265625}, {"start": 1519.69, "end": 1519.93, "word": " هنا", "probability": 0.58056640625}], "temperature": 1.0}, {"id": 61, "seek": 155218, "start": 1524.42, "end": 1552.18, "text": "هي ال money supply وهي ال money demand MD1E1R1QM1 تمام؟ بدي أفترض أنا التغيير اللي جيت بدي يدخل ع مين؟ ع ال money demand مش ال money supply يعني suppose أنه ال income زاد increasing في ال income وين بيوديني؟", "tokens": [3224, 1829, 2423, 1460, 5847, 37037, 1829, 2423, 1460, 4733, 22521, 16, 36, 16, 49, 16, 48, 44, 16, 46811, 10943, 22807, 4724, 16254, 5551, 5172, 2655, 43042, 41850, 16712, 17082, 1829, 13546, 13672, 1829, 10874, 36081, 4724, 16254, 7251, 3215, 9778, 1211, 6225, 3714, 9957, 22807, 6225, 2423, 1460, 4733, 37893, 2423, 1460, 5847, 37495, 22653, 7297, 14739, 3224, 2423, 5742, 30767, 18513, 5662, 8978, 2423, 5742, 4032, 9957, 4724, 1829, 23328, 9957, 1829, 22807], "avg_logprob": -0.26197238866384925, "compression_ratio": 1.5368421052631578, "no_speech_prob": 0.0, "words": [{"start": 1524.42, "end": 1524.68, "word": "هي", "probability": 0.784912109375}, {"start": 1524.68, "end": 1524.82, "word": " ال", "probability": 0.72314453125}, {"start": 1524.82, "end": 1524.94, "word": " money", "probability": 0.439208984375}, {"start": 1524.94, "end": 1525.44, "word": " supply", "probability": 0.966796875}, {"start": 1525.44, "end": 1528.12, "word": " وهي", "probability": 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1556.09, "end": 1572.73, "text": "لإيش؟ لأ بيزود ال money demand احنا قولنا مين طلبه اكتر على النقود؟ الغني بطلب مصاري اكتر طب استنى شوية بلاش ال income عشان ما تعملناكش قصة ال prices ده اللي محطه في ال bank", "tokens": [1211, 28814, 1829, 8592, 22807, 5296, 10721, 4724, 1829, 11622, 23328, 2423, 1460, 4733, 1975, 5016, 8315, 12174, 12610, 8315, 3714, 9957, 23032, 46152, 3224, 1975, 4117, 2655, 2288, 15844, 28239, 4587, 23328, 22807, 6024, 118, 22653, 4724, 9566, 46152, 3714, 9381, 9640, 1829, 1975, 4117, 2655, 2288, 23032, 3555, 44713, 1863, 7578, 13412, 2407, 10632, 4724, 15040, 8592, 2423, 5742, 6225, 8592, 7649, 19446, 6055, 25957, 1211, 8315, 4117, 8592, 12174, 9381, 3660, 2423, 7901, 11778, 3224, 13672, 1829, 3714, 5016, 9566, 3224, 8978, 2423, 3765], "avg_logprob": -0.2365056797862053, "compression_ratio": 1.4766839378238341, "no_speech_prob": 1.1920928955078125e-07, "words": [{"start": 1556.09, "end": 1556.77, "word": "لإيش؟", "probability": 0.70556640625}, {"start": 1556.77, 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{"start": 1562.77, "end": 1564.21, "word": " الغني", "probability": 0.9090169270833334}, {"start": 1564.21, "end": 1565.51, "word": " بطلب", "probability": 0.8623046875}, {"start": 1565.51, "end": 1565.87, "word": " مصاري", "probability": 0.815185546875}, {"start": 1565.87, "end": 1566.27, "word": " اكتر", "probability": 0.9541015625}, {"start": 1566.27, "end": 1567.05, "word": " طب", "probability": 0.7113037109375}, {"start": 1567.05, "end": 1567.43, "word": " استنى", "probability": 0.8068033854166666}, {"start": 1567.43, "end": 1567.63, "word": " شوية", "probability": 0.91943359375}, {"start": 1567.63, "end": 1567.95, "word": " بلاش", "probability": 0.77392578125}, {"start": 1567.95, "end": 1568.05, "word": " ال", "probability": 0.990234375}, {"start": 1568.05, "end": 1568.29, "word": " income", "probability": 0.9677734375}, {"start": 1568.29, "end": 1568.49, "word": " عشان", "probability": 0.98193359375}, {"start": 1568.49, "end": 1568.59, "word": " ما", "probability": 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يعني .. يعني اذا الفقير بيشتري الكمية واحدة واحدة هو بيشتري سبع كميات .. سبع واحدات مصبوط وبتالي he needs more money to buy things صح؟ وبتالي ال money demand هيزيد تمام؟ اللي خلينا نشتغل على ال prices زيادة ال prices شو بتعمل؟", "tokens": [3555, 8592, 2655, 2288, 5551, 4117, 2655, 2288, 2423, 1230, 295, 16856, 8608, 3555, 34268, 3224, 5551, 4117, 2655, 2288, 9154, 27188, 4587, 13546, 20328, 5016, 22807, 37495, 22653, 4386, 37495, 22653, 1975, 15730, 27188, 4587, 13546, 4724, 1829, 8592, 2655, 16572, 2423, 24793, 10632, 36764, 24401, 3660, 36764, 24401, 3660, 31439, 4724, 1829, 8592, 2655, 16572, 8608, 3555, 3615, 9122, 2304, 1829, 9307, 4386, 8608, 3555, 3615, 36764, 24401, 9307, 3714, 9381, 3555, 2407, 9566, 46599, 2655, 6027, 1829, 415, 2203, 544, 1460, 281, 2256, 721, 20328, 5016, 22807, 46599, 2655, 6027, 1829, 2423, 1460, 4733, 8032, 1829, 11622, 25708, 46811, 10943, 22807, 13672, 1829, 16490, 20292, 8315, 8717, 8592, 2655, 17082, 1211, 15844, 2423, 7901, 30767, 1829, 18513, 3660, 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