-ValueSIB
 Memantine ER
332
76.8 ± 17.5
2.7 ± 11.2
2.6 [1.0, 4.2]
0.001
 Placebo
327
75.2 ± 19.3
0.3 ± 11.5
CIBIC
extended-release memantine
placebo
ADCS–ADL 19 19-item Alzheimer’s Disease Cooperative Study–Activities of Daily Living