After the NUT period, participants showed a significant reduction in MRS score (18.4±5.4) in comparison to baseline (28.4±5) and the placebo period (28±5.2) (P<0.0001 for both comparisons) (Figure 2).
probiotics plus NUT for 4 weeks, followed by a 4-week treatment with probiotics plus placebo 
probiotics plus placebo over 4 weeks, followed by a 4-week treatment with probiotics plus NUT
high-density lipoprotein cholesterol plasma concentration