We also evaluated the changes in inflammatory markers between the two groups. Again, no statistical differences were apparent. Although there were no differences between the two groups, hsCRP, and adiponectin showed more favorable change in the treatment group than in the placebo group. Other inflammatory markers were not shown as expected, but TNF-α was decreased in both groups after intervention (Table 3). 
anti-inflammatory agent (Diacerein treatment group)
placebo
mean changes in body weight, BMI, and waist circumference