text_1: Knockout proximal tubule-specific deletion of the BMP receptor Alk3 causes epithelial damage.
text_2: A structure-function analysis of the BMP-Alk3-BMP receptor, type 2 (BMPR2) ligand-receptor complex, along with synthetic organic chemistry, led us to construct a library of small peptide agonists of BMP signaling that function through the Alk3 receptor.