text_1: Glucose restriction to 0.05% reduces RLS (replicative life span) by 20-40% in S. cerevisiae.
text_2: This extension was not observed in strains mutant for SIR2 (which encodes the silencing protein Sir2p) or NPT1 (a gene in a pathway in the synthesis of NAD, the oxidized form of nicotinamide adenine dinucleotide).