text_1: Female carriers of the Apolipoprotein E4 (APOE4) allele have increased risk for Alzheimer's disease.
text_2: However, after adjusting for multiple covariates, women with natural menopause and more reproductive years had an increased risk of dementia (adjusted rate ratio [RR] for women with >39 reproductive years [highest quartile] compared with <34 reproductive years [lowest quartile], 1.78; 95% confidence interval [CI], 1.12-2.84).