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  ---
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  dataset_info:
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  features:
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- - name: image
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- dtype: image
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- - name: label
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- dtype:
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- class_label:
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- names:
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- 0: control
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- 1: sick
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  config_name: SDH_16k
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  splits:
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- - name: test
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- num_bytes: 683067
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- num_examples: 3358
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- - name: train
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- num_bytes: 2466024
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- num_examples: 12085
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- - name: validation
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- num_bytes: 281243
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- num_examples: 1344
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  download_size: 2257836789
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  dataset_size: 3430334
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  annotations_creators:
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- - expert-generated
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  language: []
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  language_creators:
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- - expert-generated
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  license:
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- - agpl-3.0
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  multilinguality: []
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  pretty_name: SDH staining muscle fiber histology images used to train MyoQuant model.
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  size_categories:
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- - 10K<n<100K
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  source_datasets:
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- - original
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  tags:
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- - myology
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- - biology
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- - histology
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- - muscle
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- - cells
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- - fibers
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- - myopathy
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- - SDH
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- - myoquant
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  task_categories:
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- - image-classification
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  ---
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  # Dataset Card for MyoQuant SDH Data
@@ -56,119 +56,107 @@ task_categories:
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  - [Table of Contents](#table-of-contents)
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  - [Dataset Description](#dataset-description)
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  - [Dataset Summary](#dataset-summary)
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- - [Supported Tasks and Leaderboards](#supported-tasks-and-leaderboards)
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- - [Languages](#languages)
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  - [Dataset Structure](#dataset-structure)
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- - [Data Instances](#data-instances)
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- - [Data Fields](#data-fields)
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- - [Data Splits](#data-splits)
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- - [Dataset Creation](#dataset-creation)
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- - [Curation Rationale](#curation-rationale)
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- - [Source Data](#source-data)
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- - [Annotations](#annotations)
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  - [Personal and Sensitive Information](#personal-and-sensitive-information)
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  - [Considerations for Using the Data](#considerations-for-using-the-data)
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  - [Social Impact of Dataset](#social-impact-of-dataset)
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- - [Discussion of Biases](#discussion-of-biases)
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- - [Other Known Limitations](#other-known-limitations)
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  - [Additional Information](#additional-information)
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- - [Dataset Curators](#dataset-curators)
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  - [Licensing Information](#licensing-information)
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  - [Citation Information](#citation-information)
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- - [Contributions](#contributions)
 
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  ## Dataset Description
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- - **Homepage:**
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- - **Repository:**
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- - **Paper:**
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- - **Leaderboard:**
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- - **Point of Contact:**
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  ### Dataset Summary
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- [More Information Needed]
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-
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- ### Supported Tasks and Leaderboards
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-
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- [More Information Needed]
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-
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- ### Languages
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-
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- [More Information Needed]
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  ## Dataset Structure
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- ### Data Instances
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-
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- [More Information Needed]
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-
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- ### Data Fields
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- [More Information Needed]
 
 
 
 
 
 
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- ### Data Splits
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- [More Information Needed]
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- ## Dataset Creation
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- ### Curation Rationale
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- [More Information Needed]
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- ### Source Data
 
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- #### Initial Data Collection and Normalization
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- [More Information Needed]
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- #### Who are the source language producers?
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-
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- [More Information Needed]
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-
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- ### Annotations
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-
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- #### Annotation process
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- [More Information Needed]
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- #### Who are the annotators?
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- [More Information Needed]
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- ### Personal and Sensitive Information
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- [More Information Needed]
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- ## Considerations for Using the Data
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- ### Social Impact of Dataset
 
 
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- [More Information Needed]
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- ### Discussion of Biases
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- [More Information Needed]
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- ### Other Known Limitations
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- [More Information Needed]
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- ## Additional Information
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- ### Dataset Curators
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- [More Information Needed]
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- ### Licensing Information
 
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- [More Information Needed]
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- ### Citation Information
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- [More Information Needed]
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- ### Contributions
 
 
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- Thanks to [@github-username](https://github.com/<github-username>) for adding this dataset.
 
1
  ---
2
  dataset_info:
3
  features:
4
+ - name: image
5
+ dtype: image
6
+ - name: label
7
+ dtype:
8
+ class_label:
9
+ names:
10
+ 0: control
11
+ 1: sick
12
  config_name: SDH_16k
13
  splits:
14
+ - name: test
15
+ num_bytes: 683067
16
+ num_examples: 3358
17
+ - name: train
18
+ num_bytes: 2466024
19
+ num_examples: 12085
20
+ - name: validation
21
+ num_bytes: 281243
22
+ num_examples: 1344
23
  download_size: 2257836789
24
  dataset_size: 3430334
25
  annotations_creators:
26
+ - expert-generated
27
  language: []
28
  language_creators:
29
+ - expert-generated
30
  license:
31
+ - agpl-3.0
32
  multilinguality: []
33
  pretty_name: SDH staining muscle fiber histology images used to train MyoQuant model.
34
  size_categories:
35
+ - 10K<n<100K
36
  source_datasets:
37
+ - original
38
  tags:
39
+ - myology
40
+ - biology
41
+ - histology
42
+ - muscle
43
+ - cells
44
+ - fibers
45
+ - myopathy
46
+ - SDH
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+ - myoquant
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  task_categories:
49
+ - image-classification
50
  ---
51
 
52
  # Dataset Card for MyoQuant SDH Data
 
56
  - [Table of Contents](#table-of-contents)
57
  - [Dataset Description](#dataset-description)
58
  - [Dataset Summary](#dataset-summary)
 
 
59
  - [Dataset Structure](#dataset-structure)
60
+ - [Data Instances and Splits](#data-instances-and-splits)
61
+ - [Dataset Creation and Annotations](#dataset-creation-and-annotations)
62
+ - [Source Data and annotation process](#source-data-and-annotation-process)
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+ - [Who are the annotators ?](#who-are-the-annotators)
 
 
 
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  - [Personal and Sensitive Information](#personal-and-sensitive-information)
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  - [Considerations for Using the Data](#considerations-for-using-the-data)
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  - [Social Impact of Dataset](#social-impact-of-dataset)
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+ - [Discussion of Biases and Limitations](#discussion-of-biases-and-limitations)
 
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  - [Additional Information](#additional-information)
 
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  - [Licensing Information](#licensing-information)
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  - [Citation Information](#citation-information)
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+ - [The Team Behind this Dataset](#the-team-behind-this-dataset)
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+ - [Partners](#partners)
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  ## Dataset Description
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+ - **Homepage:** https://github.com/lambda-science/MyoQuant
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+ - **Repository:** https://huggingface.co/corentinm7/MyoQuant-SDH-Model
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+ - **Paper:** Yet To Come
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+ - **Leaderboard:** N/A
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+ - **Point of Contact:** [**Corentin Meyer**, 3rd year PhD Student in the CSTB Team, ICube — CNRS — Unistra](https://cmeyer.fr) email: <corentin.meyer@etu.unistra.fr>
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  ### Dataset Summary
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+ This dataset contains images of individual muscle fiber used to train [MyoQuant](https://github.com/lambda-science/MyoQuant) SDH Model. The goal of these data is to train a tool to classify SDH stained muscle fibers depending on the presence of mitochondria repartition anomalies. A pathological feature useful for diagnosis and classification in patient with congenital myopathies.
 
 
 
 
 
 
 
 
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  ## Dataset Structure
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+ ### Data Instances and Splits
 
 
 
 
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+ A total of 16 787 single muscle fiber images are in the dataset, split in three sets: train, validation and test set.
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+ See the table for the exact count of images in each category:
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+ | | Train (72%) | Validation (8%) | Test (20%) | TOTAL |
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+ |---------|-------------|-----------------|------------|-------------|
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+ | control | 9165 | 1019 | 2546 | 12730 (76%) |
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+ | sick | 2920 | 325 | 812 | 4057 (24%) |
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+ | TOTAL | 12085 | 1344 | 3358 | 16787 |
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+ ## Dataset Creation and Annotations
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+ ### Source Data and annotation process
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+ To create this dataset of single muscle images, whole slide image of mice muscle fiber with SDH staining were taken from WT mice (1), BIN1 KO mice (10) and mutated DNM mice (7). Cells contained within these slides manually counted, labeled and classified in two categories: control (no anomaly) or sick (mitochondria anomaly) by two experts/annotators. Then all single muscle images were extracted from the image using CellPose to detect each individual cell’s boundaries. Resulting in 16787 images from 18 whole image slides.
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+ ### Who are the annotators?
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+ All data in this dataset were generated and manually annotated by two experts:
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+ - [**Quentin GIRAUD, PhD Student**](https://twitter.com/GiraudGiraud20) @ [Department Translational Medicine, IGBMC, CNRS UMR 7104](https://www.igbmc.fr/en/recherche/teams/pathophysiology-of-neuromuscular-diseases), 1 rue Laurent Fries, 67404 Illkirch, France <quentin.giraud@igbmc.fr>
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+ - **Charlotte GINESTE, Post-Doc** @ [Department Translational Medicine, IGBMC, CNRS UMR 7104](https://www.igbmc.fr/en/recherche/teams/pathophysiology-of-neuromuscular-diseases), 1 rue Laurent Fries, 67404 Illkirch, France <charlotte.gineste@igbmc.fr>
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+ A second pass of verification was done by:
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+ - **Bertrand VERNAY, Platform Leader** @ [Light Microscopy Facility, IGBMC, CNRS UMR 7104](https://www.igbmc.fr/en/plateformes-technologiques/photonic-microscopy), 1 rue Laurent Fries, 67404 Illkirch, France <bertrand.vernay@igbmc.fr>
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+ ### Personal and Sensitive Information
 
 
 
 
 
 
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+ All image data comes from mice, there is no personal nor sensitive information in this dataset.
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+ ## Considerations for Using the Data
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+ ### Social Impact of Dataset
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+ The aim of this dataset is to improve congenital myopathies diagnosis by providing tools to automatically quantify specific pathogenic features in muscle fiber histology images.
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+ ### Discussion of Biases and Limitations
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+ This dataset has several limitations (non-exhaustive list):
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+ - The images are from mice and thus might not be ideal to represent actual mechanism in human muscle
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+ - The image comes only from two mice models with mutations in two genes (BIN1, DNM) while congenital myopathies can be caused by a mutation in more than 35+ genes.
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+ - Only mitochondria anomaly was considered to classify cells as "sick", other anomalies were not considered, thus control cells might present other anomalies (such as what is called "cores" in congenital myopathies for examples)
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+ ## Additional Information
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+ ### Licensing Information
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+ This dataset is under the GNU AFFERO GENERAL PUBLIC LICENSE Version 3, to ensure that what's open-source, stays open-source and available to the community.
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+ ### Citation Information
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+ MyoQuant publication with model and data is yet to come.
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+ ## The Team Behind this Dataset
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+ **The creator, uploader and main maintainer of this dataset, associated model and MyoQuant is: [Corentin Meyer, 3rd year PhD Student in the CSTB Team, ICube — CNRS — Unistra](https://cmeyer.fr) Email: <corentin.meyer@etu.unistra.fr> Github: [@lambda-science](https://github.com/lambda-science)**
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+ Special thanks to the experts that created the data for this dataset and all the time they spend counting cells :
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+ - **Quentin GIRAUD, PhD Student** @ [Department Translational Medicine, IGBMC, CNRS UMR 7104](https://www.igbmc.fr/en/recherche/teams/pathophysiology-of-neuromuscular-diseases), 1 rue Laurent Fries, 67404 Illkirch, France <quentin.giraud@igbmc.fr>
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+ - **Charlotte GINESTE, Post-Doc** @ [Department Translational Medicine, IGBMC, CNRS UMR 7104](https://www.igbmc.fr/en/recherche/teams/pathophysiology-of-neuromuscular-diseases), 1 rue Laurent Fries, 67404 Illkirch, France <charlotte.gineste@igbmc.fr>
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+ Last but not least thanks to Bertrand Vernay being at the origin of this project:
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+ - **Bertrand VERNAY, Platform Leader** @ [Light Microscopy Facility, IGBMC, CNRS UMR 7104](https://www.igbmc.fr/en/plateformes-technologiques/photonic-microscopy), 1 rue Laurent Fries, 67404 Illkirch, France <bertrand.vernay@igbmc.fr>
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+ ## Partners
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+ <p align="center">
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+ <img src="https://i.imgur.com/m5OGthE.png" alt="Partner Banner" style="border-radius: 25px;" />
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+ </p>
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+ MyoQuant-SDH-Data is born within the collaboration between the [CSTB Team @ ICube](https://cstb.icube.unistra.fr/en/index.php/Home) led by Julie D. Thompson, the [Morphological Unit of the Institute of Myology of Paris](https://www.institut-myologie.org/en/recherche-2/neuromuscular-investigation-center/morphological-unit/) led by Teresinha Evangelista, the [imagery platform MyoImage of Center of Research in Myology](https://recherche-myologie.fr/technologies/myoimage/) led by Bruno Cadot, [the photonic microscopy platform of the IGMBC](https://www.igbmc.fr/en/plateformes-technologiques/photonic-microscopy) led by Bertrand Vernay and the [Pathophysiology of neuromuscular diseases team @ IGBMC](https://www.igbmc.fr/en/igbmc/a-propos-de-ligbmc/directory/jocelyn-laporte) led by Jocelyn Laporte