risks-factors / H00026.json
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risk factors
c8f8834 unverified
{
"id": "H00026",
"disease": {
"id": "H00026",
"names": [
"Endometrial cancer"
],
"dbLinks": {
"icd10": [
"C54"
],
"mesh": [
"D016889"
]
},
"category": "Cancer"
},
"riskFactors": [
{
"text": "dyslipidemia",
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{
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{
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{
"text": "decreased serum adiponectin or increased visfatin levels",
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{
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{
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{
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{
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{
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{
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{
"text": "delivery of a large-for-gestational-age infant, and preeclampsia",
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"text": "hyperlipidemia, thyroid cancer and liver cancer",
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{
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"text": "higher levels of cancer antigen 125 (ca 125)",
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"text": "current use of estrogen-only and estrogen plus progestin fmh",
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"text": "uterine fibroids, higher body mass index",
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"text": "deep myometrial invasion, positive peritoneal cytology, and lvsi",
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"text": "spec patients having greater than a 10-year interval from prior malignancy",
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"text": "myometrial invasion of 50% or greater and lvsi",
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"text": "obesity, and polycystic ovary syndrome (pcos)",
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"text": "insulin levels",
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"text": "blood cadmium concentration above the median",
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"text": "codon 389 polymorphism of pict-1",
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"text": "uterine volume and weight \u003e 75th percentile and chemotherapy",
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"text": "visceral adiposity tissue",
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"text": "women with a family history of bc",
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
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{
"text": "\u003e 50% myometrial invasion, undifferentiated nonendometrioid tumors",
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{
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{
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{
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{
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{
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{
"text": "insulin resistance, and genetic risk",
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{
"text": "diabetics",
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{
"text": "the tamoxifen use group",
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{
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{
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{
"text": "in women with than without endometriosis",
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{
"text": "preoperative ah patients",
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{
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{
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{
"text": "aub_group and et_group",
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{
"text": "for women whose menopausal age over 46.5 years old",
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{
"text": "the mpo polymorphism",
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{
"text": "high dietary gi/gl with increased risk of some cancers. high dietary gi",
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{
"text": "women previously treated with tamoxifen",
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{
"text": "women with pcos at reproductive age",
"score": 9.515401840209961,
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{
"text": "among women with ovarian endometriosis",
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{
"text": "the highest versus the lowest age at menopause",
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{
"text": "women with ec aged ≥65 years",
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{
"text": "among obese patients, those with class i obesity (bmi 30 to 34.9 kg/m)",
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{
"text": "women in the third tertile",
"score": 9.482192039489746,
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{
"text": "first full-term pregnancy",
"score": 9.477840423583984,
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{
"text": "women with endometrial cancer (ec)",
"score": 9.4771089553833,
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{
"text": "human epididymis secretory protein e4 (he4)",
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{
"text": "pcos cohort",
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{
"text": "size of sln metastasis",
"score": 9.460137367248535,
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{
"text": "age, bmi, and radiation exposure",
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{
"text": "mean body mass index (bmi) of ≥30",
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{
"text": "first 6 months after cholecystectomy",
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{
"text": "the highest dose-responses per 50 g increases in processed meat intake",
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{
"text": "subfertility",
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{
"text": "women with a menstrual cycle length of 28-30 days",
"score": 9.42530632019043,
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},
{
"text": "cancer antigen 125 (ca125)",
"score": 9.423328399658203,
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{
"text": "bmi ≥40kg/m",
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{
"text": "subtotal hysterectomy (sh) for postmenopausal women scheduled for sc for pop",
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{
"text": "intentional weight loss in postmenopausal women",
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{
"text": "laparoscopically confirmed endometriosis",
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{
"text": "early coitarche (30, 60%), or having an abortion",
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{
"text": "patients with lynch syndrome",
"score": 9.383005142211914,
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{
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{
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{
"text": "pelvic floor repair (pfr) for pelvic organ prolapse (pop)",
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{
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{
"text": ", obesity (bmi ≥ 27)",
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{
"text": "high-risk uterine factors",
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{
"text": "history of fractures, especially of the hip",
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{
"text": "polycystic ovary syndrome, type 2 diabetes mellitus",
"score": 9.328758239746094,
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{
"text": "each 5 μg/ml increase in adiponectin",
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},
{
"text": "high body mass index, or comorbidities",
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{
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{
"text": "raised blood pressure, and hyperglycemia",
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{
"text": "higher intake of total flavonoids",
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"text": "butter intake",
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"text": "metabolic signature of bmi (or 1.50, 95% ci 1.30-1.74), wc",
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{
"text": "a mean number of lymph nodes dissected of \u003c21",
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{
"text": "hiv",
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{
"text": "and later age at first birth (≥30 vs. \u003c20 years",
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{
"text": "patients' menopausal status",
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{
"text": "synthetic estrogens and progestins",
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{
"text": "presence of gc at the preoperative cervical smear",
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{
"text": "insulin/igf axis",
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{
"text": "obesity and insulin resistance in women with benign endometrium",
"score": 9.240066528320312,
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},
{
"text": "unrecognized and inadequately treated cardiovascular risk factors",
"score": 9.237394332885742,
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{
"text": "anti-mullerian hormone (amh)",
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{
"text": "obese women with cancer",
"score": 9.231912612915039,
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},
{
"text": "women with a brca pathogenic variant",
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},
{
"text": "frail patients",
"score": 9.217018127441406,
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{
"text": "patients with abnormal pap smears",
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{
"text": "estrogen signaling",
"score": 9.216060638427734,
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{
"text": "neutrophil to lymphocyte ratio",
"score": 9.208439826965332,
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},
{
"text": "ageing women with pcos",
"score": 9.198779106140137,
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},
{
"text": "the polycystic ovary syndrome (pcos)",
"score": 9.194862365722656,
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},
{
"text": "sleep disturbances",
"score": 9.192562103271484,
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{
"text": "greater inflammatory potential",
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{
"text": "brain-tissue bmi",
"score": 9.160123825073242,
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{
"text": "radiation therapy (hr: 1.73, 95% ci: 1.29, 2.31), and chemotherapy",
"score": 9.156654357910156,
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},
{
"text": "high kaposi-sarcoma-associated-herpesvirus titres",
"score": 9.154918670654297,
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{
"text": "chronologic age",
"score": 9.151895523071289,
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{
"text": "genetic risk of lynch syndrome",
"score": 9.144543647766113,
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{
"text": "high doses or many cycles of clomiphene citrate",
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{
"text": "glandular cells (gc)",
"score": 9.140026092529297,
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},
{
"text": "advanced stage and high-risk histology",
"score": 9.138528823852539,
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},
{
"text": "bmi is associated to figo stage and endometrial sampling (es)",
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},
{
"text": "older age, advanced stage and high-risk histology",
"score": 9.125609397888184,
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},
{
"text": "bilateral oophorectomy vs no oophorectomy",
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},
{
"text": "higher-risk groups",
"score": 9.099695205688477,
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},
{
"text": "lvsi-positive tumors and negative lymph nodes",
"score": 9.0936918258667,
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]
},
{
"text": "glomerular filtration rate (gfr)",
"score": 9.091771125793457,
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]
},
{
"text": "advanced stage and high-risk histology-",
"score": 9.068955421447754,
"articlesIDs": [
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]
},
{
"text": "vh for pop",
"score": 9.067338943481445,
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]
},
{
"text": "women who first reported infertility earlier in life (≤25 years",
"score": 9.06612777709961,
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]
},
{
"text": "having a higher body mass index (bmi) at baseline or age 21 years was",
"score": 9.057575225830078,
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]
},
{
"text": "obesity (bmi≥30",
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]
},
{
"text": "older age, advanced stage and high-risk histology-",
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]
},
{
"text": "postmenopausal women with asymptomatic endometrial thickening",
"score": 9.051166534423828,
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]
},
{
"text": "smokers (aor= 0.53 95% ci: 0.43 - 0.65; value: \u003c.001), and divorced women",
"score": 9.045469284057617,
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},
{
"text": "women with pcos are metabolically obese. pcos",
"score": 9.043606758117676,
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]
},
{
"text": "arg399gln and arg194trp variants",
"score": 9.038500785827637,
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},
{
"text": "il.\n\nconclusion:\nwe concluded a weak association between dietary gi/gl",
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]
},
{
"text": "uterine risk factors (low-, intermediate-, and high-)",
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{
"text": "oral contraceptives (oc) (potentially modifiable)",
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{
"text": "flavones",
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{
"text": "age (or 1.14, 95% ci 1.1-1.2) and bmi",
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{
"text": "concentration of cd",
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{
"text": "nonendometrioid grade 1 or 2, lymphovascular invasion, and volume index ≥36",
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{
"text": "the first 6 months after cholecystectomy",
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},
{
"text": "serum levels of he4 and ca125",
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{
"text": "metabolic aberrations",
"score": 8.975089073181152,
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{
"text": "rs11649743 g (or = 1.138, p = 1.08 × 10), rs3760511 c",
"score": 8.97431755065918,
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]
},
{
"text": "women with endometrial cancer had higher proportions of obesity (bmi≥30",
"score": 8.968660354614258,
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{
"text": "hypertriglyceridemia",
"score": 8.968440055847168,
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{
"text": "ca125 in involvement of the ovaries",
"score": 8.961048126220703,
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]
},
{
"text": "in women with obesity (body mass index (bmi) \u003e 25)",
"score": 8.931541442871094,
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]
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{
"text": "in patients with diffuse lvsi",
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{
"text": "reproduction, insulin resistance",
"score": 8.906413078308105,
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{
"text": "asian bmi standard for obesity at 25 kg/m2",
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{
"text": "hei-2005 and ahei-2010 indices",
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{
"text": "abnormal cervical cytology",
"score": 8.890970230102539,
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{
"text": "age-associated scnas and mutations",
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{
"text": "one session of mvpa 5 years pre-interview",
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{
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