H00036.json

{
 "id": "H00036",
 "disease": {
  "id": "H00036",
  "names": [
   "Osteosarcoma",
   "SUPERGRP  Solid tumor [DS:H02421]"
  ],
  "dbLinks": {
   "icd10": [
    "C41"
   ],
   "mesh": [
    "D012516"
   ]
  },
  "category": "Cancer"
 },
 "riskFactors": [
  {
   "text": "genetic syndromes",
   "score": 13.990296363830566,
   "articlesIDs": [
    "19460580"
   ]
  },
  {
   "text": "obesity and lameness",
   "score": 13.977620124816895,
   "articlesIDs": [
    "36733647"
   ]
  },
  {
   "text": "family history of cancer",
   "score": 13.92774486541748,
   "articlesIDs": [
    "19618453"
   ]
  },
  {
   "text": "body condition score (bcs)",
   "score": 13.907001495361328,
   "articlesIDs": [
    "36733647"
   ]
  },
  {
   "text": "prior radiation exposure, and genetic syndromes",
   "score": 13.90496826171875,
   "articlesIDs": [
    "19460580"
   ]
  },
  {
   "text": "gonadectomized dogs, body condition score (bcs)",
   "score": 13.874046325683594,
   "articlesIDs": [
    "36733647"
   ]
  },
  {
   "text": "high birth weight",
   "score": 13.797876358032227,
   "articlesIDs": [
    "17106438",
    "28338660",
    "26371026"
   ]
  },
  {
   "text": "antineoplastic drugs, and ionizing radiation",
   "score": 13.753583908081055,
   "articlesIDs": [
    "16324620"
   ]
  },
  {
   "text": "high fluoride exposure",
   "score": 13.745940208435059,
   "articlesIDs": [
    "19618453"
   ]
  },
  {
   "text": "horticulture and pesticide indicators",
   "score": 13.745834350585938,
   "articlesIDs": [
    "8543394"
   ]
  },
  {
   "text": "fathers in farming",
   "score": 13.70937728881836,
   "articlesIDs": [
    "9839731"
   ]
  },
  {
   "text": "breeds with dolichocephalic skull conformation",
   "score": 13.693964004516602,
   "articlesIDs": [
    "37365662"
   ]
  },
  {
   "text": "hereditary retinoblastoma",
   "score": 13.653057098388672,
   "articlesIDs": [
    "16324620"
   ]
  },
  {
   "text": "gstp1 and gstt1 null genotype",
   "score": 13.646923065185547,
   "articlesIDs": [
    "30909663"
   ]
  },
  {
   "text": "li-fraumeni syndrome, antineoplastic drugs, and ionizing radiation",
   "score": 13.600790977478027,
   "articlesIDs": [
    "16324620"
   ]
  },
  {
   "text": "mothers in managerial and administrative work",
   "score": 13.597893714904785,
   "articlesIDs": [
    "9839731"
   ]
  },
  {
   "text": "hereditary retinoblastoma, li-fraumeni syndrome, antineoplastic drugs",
   "score": 13.582279205322266,
   "articlesIDs": [
    "16324620"
   ]
  },
  {
   "text": "paget's disease, hereditary retinoblastoma",
   "score": 13.563541412353516,
   "articlesIDs": [
    "16324620"
   ]
  },
  {
   "text": "individuals with high birth-weight (≥ 4,046 g)",
   "score": 13.534822463989258,
   "articlesIDs": [
    "21465145"
   ]
  },
  {
   "text": "mothers in teaching",
   "score": 13.534428596496582,
   "articlesIDs": [
    "9839731"
   ]
  },
  {
   "text": "individuals with high birth weight",
   "score": 13.533501625061035,
   "articlesIDs": [
    "26371026"
   ]
  },
  {
   "text": "hypoalbuminemia (albumin \u003c 2.8 g/dl)",
   "score": 13.508732795715332,
   "articlesIDs": [
    "30554419"
   ]
  },
  {
   "text": "patients with osteosarcoma",
   "score": 13.47903823852539,
   "articlesIDs": [
    "12544770",
    "21616236",
    "23701776"
   ]
  },
  {
   "text": "high versus normal salp and weight (kg)",
   "score": 13.460471153259277,
   "articlesIDs": [
    "24054333"
   ]
  },
  {
   "text": "handling of drugs, exposure to anaesthetics and infections during pregnancy",
   "score": 13.428998947143555,
   "articlesIDs": [
    "1832903"
   ]
  },
  {
   "text": "xrcc3 thr241met gene polymorphism",
   "score": 13.421541213989258,
   "articlesIDs": [
    "26617908"
   ]
  },
  {
   "text": "co-infection with human herpes virus 8 (hhv-8)",
   "score": 13.420636177062988,
   "articlesIDs": [
    "19460580"
   ]
  },
  {
   "text": "ctla-4 +49a/g variant",
   "score": 13.394052505493164,
   "articlesIDs": [
    "27644617"
   ]
  },
  {
   "text": "positive lymph nodes and other site-specific metastases (ssm)",
   "score": 13.377312660217285,
   "articlesIDs": [
    "37437020"
   ]
  },
  {
   "text": "parental farming and residence on a farm, younger age at puberty",
   "score": 13.35464096069336,
   "articlesIDs": [
    "19618453"
   ]
  },
  {
   "text": "exposure to epipodophyllotoxins and anthracyclines",
   "score": 13.348213195800781,
   "articlesIDs": [
    "12637473"
   ]
  },
  {
   "text": "patients with osteosarcoma and pet positive disease at original presentation",
   "score": 13.31498908996582,
   "articlesIDs": [
    "23701776"
   ]
  },
  {
   "text": "higher tumor grade, bigger tumor size, positive lymph nodes",
   "score": 13.296942710876465,
   "articlesIDs": [
    "37437020"
   ]
  },
  {
   "text": "longer leg or longer skull length",
   "score": 13.29138469696045,
   "articlesIDs": [
    "37365662"
   ]
  },
  {
   "text": "radiotherapy",
   "score": 13.290900230407715,
   "articlesIDs": [
    "22340225",
    "16152578",
    "34608566"
   ]
  },
  {
   "text": "ctla-4 +49g\u003ea polymorphism",
   "score": 13.263816833496094,
   "articlesIDs": [
    "23900675",
    "27644617"
   ]
  },
  {
   "text": "chondrodystrophic breeds",
   "score": 13.25985336303711,
   "articlesIDs": [
    "37365662"
   ]
  },
  {
   "text": "taller than average (51st - 89th percentile)",
   "score": 13.252481460571289,
   "articlesIDs": [
    "21465145"
   ]
  },
  {
   "text": "individuals carrying null gstm1 and gstt1",
   "score": 13.249475479125977,
   "articlesIDs": [
    "22471480"
   ]
  },
  {
   "text": "aa genotype of -308 g/a locus of tnf-α gene",
   "score": 13.248665809631348,
   "articlesIDs": [
    "26097610"
   ]
  },
  {
   "text": "histology types (osteosarcoma and ewing sarcoma)",
   "score": 13.237191200256348,
   "articlesIDs": [
    "31996232"
   ]
  },
  {
   "text": "alkylating agent score (aas)",
   "score": 13.228202819824219,
   "articlesIDs": [
    "25192682"
   ]
  },
  {
   "text": "tt genotype of vegf +936c/t genetic variants",
   "score": 13.223617553710938,
   "articlesIDs": [
    "26600515"
   ]
  },
  {
   "text": "children of fathers employed in the manufacture of iron and metal structures",
   "score": 13.202409744262695,
   "articlesIDs": [
    "1832903"
   ]
  },
  {
   "text": "history of lameness condition(s) (other than osa)",
   "score": 13.200297355651855,
   "articlesIDs": [
    "36733647"
   ]
  },
  {
   "text": "female sex and a higher rate of administration of doxorubicin",
   "score": 13.191253662109375,
   "articlesIDs": [
    "7760889"
   ]
  },
  {
   "text": "mmp2 rs243865 genotype",
   "score": 13.19077205657959,
   "articlesIDs": [
    "26754027"
   ]
  },
  {
   "text": "human immunodeficiency virus (hiv)",
   "score": 13.186849594116211,
   "articlesIDs": [
    "19460580"
   ]
  },
  {
   "text": "pig farming",
   "score": 13.171476364135742,
   "articlesIDs": [
    "8543394"
   ]
  },
  {
   "text": "machine repair workshops",
   "score": 13.16280746459961,
   "articlesIDs": [
    "1832903"
   ]
  },
  {
   "text": "male and female dogs that underwent gonadectomy before 1 year of age",
   "score": 13.150552749633789,
   "articlesIDs": [
    "12433723"
   ]
  },
  {
   "text": "cyp1a1 and gstm1 polymorphisms",
   "score": 13.129362106323242,
   "articlesIDs": [
    "26681006"
   ]
  },
  {
   "text": "il-6 -174 g/c genotype",
   "score": 13.12657356262207,
   "articlesIDs": [
    "26810186"
   ]
  },
  {
   "text": "high cumulative aas",
   "score": 13.11073112487793,
   "articlesIDs": [
    "25192682"
   ]
  },
  {
   "text": "14q32 mirna cluster",
   "score": 13.101707458496094,
   "articlesIDs": [
    "30337581"
   ]
  },
  {
   "text": "patients with osteosarcoma (or, 10.8), ewing sarcoma",
   "score": 13.087869644165039,
   "articlesIDs": [
    "21616236"
   ]
  },
  {
   "text": "radiotherapy without chemotherapy",
   "score": 13.078657150268555,
   "articlesIDs": [
    "16152578"
   ]
  },
  {
   "text": "serum alkaline phosphatase (salp)",
   "score": 13.012906074523926,
   "articlesIDs": [
    "24054333"
   ]
  },
  {
   "text": "cumulative dose of cisplatin",
   "score": 13.012578964233398,
   "articlesIDs": [
    "15519518"
   ]
  },
  {
   "text": "advanced age",
   "score": 13.005228042602539,
   "articlesIDs": [
    "23824394"
   ]
  },
  {
   "text": "children with fathers in social sciences",
   "score": 12.998735427856445,
   "articlesIDs": [
    "9839731"
   ]
  },
  {
   "text": "children of female nurses",
   "score": 12.987415313720703,
   "articlesIDs": [
    "1832903"
   ]
  },
  {
   "text": "tgfbr1*6a variants",
   "score": 12.979045867919922,
   "articlesIDs": [
    "20429896"
   ]
  },
  {
   "text": "ever users of pesticide",
   "score": 12.974969863891602,
   "articlesIDs": [
    "16108052"
   ]
  },
  {
   "text": "autologous stem cell transplantation (sct)",
   "score": 12.964168548583984,
   "articlesIDs": [
    "30053029"
   ]
  },
  {
   "text": "patients with ewing sarcoma and larger tumors",
   "score": 12.954680442810059,
   "articlesIDs": [
    "31996232"
   ]
  },
  {
   "text": "multiple gestation",
   "score": 12.948923110961914,
   "articlesIDs": [
    "35929579"
   ]
  },
  {
   "text": "dba",
   "score": 12.941722869873047,
   "articlesIDs": [
    "11196268"
   ]
  },
  {
   "text": "survivors of childhood osteosarcoma and ews",
   "score": 12.93303108215332,
   "articlesIDs": [
    "35059962"
   ]
  },
  {
   "text": "human immunodeficiency virus (hiv), prior radiation exposure",
   "score": 12.92782211303711,
   "articlesIDs": [
    "19460580"
   ]
  },
  {
   "text": "machine repair workshops (or = 2.8; n = 6), as machinists",
   "score": 12.927515983581543,
   "articlesIDs": [
    "1832903"
   ]
  },
  {
   "text": "woodworkers",
   "score": 12.92530345916748,
   "articlesIDs": [
    "16108052"
   ]
  },
  {
   "text": "construction workers (or = 1.62, 95% ci 0.92-2.87). ever users of pesticide",
   "score": 12.924951553344727,
   "articlesIDs": [
    "16108052"
   ]
  },
  {
   "text": "presence of hernias and ewing sarcoma; high fluoride exposure",
   "score": 12.921661376953125,
   "articlesIDs": [
    "19618453"
   ]
  },
  {
   "text": "art use",
   "score": 12.912382125854492,
   "articlesIDs": [
    "35929579"
   ]
  },
  {
   "text": "patients with esft",
   "score": 12.897407531738281,
   "articlesIDs": [
    "18353632"
   ]
  },
  {
   "text": "mothers in teaching (or = 3.1, 95% ci: 1.1-8.7) or farming",
   "score": 12.893827438354492,
   "articlesIDs": [
    "9839731"
   ]
  },
  {
   "text": "bodyweight and longer leg or longer skull length",
   "score": 12.891408920288086,
   "articlesIDs": [
    "37365662"
   ]
  },
  {
   "text": "igf2r ex16+88g\u003ea (rs998075) and ivs16+15c\u003et (rs998074) snps",
   "score": 12.886655807495117,
   "articlesIDs": [
    "17684144"
   ]
  },
  {
   "text": "younger age at puberty and family history of cancer",
   "score": 12.884915351867676,
   "articlesIDs": [
    "19618453"
   ]
  },
  {
   "text": "fathers in the social sciences",
   "score": 12.877723693847656,
   "articlesIDs": [
    "9839731"
   ]
  },
  {
   "text": "areas of low population density",
   "score": 12.876063346862793,
   "articlesIDs": [
    "22738416"
   ]
  },
  {
   "text": "woodworkers (or = 2.68, 95% ci 1.36-5.29) and construction workers",
   "score": 12.872599601745605,
   "articlesIDs": [
    "16108052"
   ]
  },
  {
   "text": "patients with osteosarcoma and lager tumors or higher tumor grade",
   "score": 12.869668006896973,
   "articlesIDs": [
    "31996232"
   ]
  },
  {
   "text": "certain occupational exposures",
   "score": 12.864771842956543,
   "articlesIDs": [
    "19460580"
   ]
  },
  {
   "text": "greyhounds, rottweilers, and great danes",
   "score": 12.856103897094727,
   "articlesIDs": [
    "17916033"
   ]
  },
  {
   "text": "areas of low population density and where more people owned cars",
   "score": 12.84727954864502,
   "articlesIDs": [
    "22738416"
   ]
  },
  {
   "text": "increasing body weight",
   "score": 12.838375091552734,
   "articlesIDs": [
    "9691849"
   ]
  },
  {
   "text": "gstp1 polymorphism",
   "score": 12.828306198120117,
   "articlesIDs": [
    "30909663"
   ]
  },
  {
   "text": "chicken farming",
   "score": 12.82253360748291,
   "articlesIDs": [
    "8543394"
   ]
  },
  {
   "text": "age at treatment and the cumulative dose of cisplatin",
   "score": 12.820053100585938,
   "articlesIDs": [
    "15519518"
   ]
  },
  {
   "text": "gstt1 polymorphism",
   "score": 12.815502166748047,
   "articlesIDs": [
    "22471480",
    "30909663"
   ]
  },
  {
   "text": "parental breast (sir 1.7) and prostate (sir 1.7) cancers",
   "score": 12.806896209716797,
   "articlesIDs": [
    "11809347"
   ]
  },
  {
   "text": "diamond-blackfan anemia (dba)",
   "score": 12.805795669555664,
   "articlesIDs": [
    "11196268"
   ]
  },
  {
   "text": "patients with age 20-39 years, male, positive lymph nodes, other ssm",
   "score": 12.804645538330078,
   "articlesIDs": [
    "37437020"
   ]
  },
  {
   "text": "tt genotype of xrcc3 thr241met",
   "score": 12.80219841003418,
   "articlesIDs": [
    "26617908"
   ]
  },
  {
   "text": "increasing standard weight and increasing standard height",
   "score": 12.795807838439941,
   "articlesIDs": [
    "9691849"
   ]
  },
  {
   "text": "patients with primary malignant bone tumors",
   "score": 12.770929336547852,
   "articlesIDs": [
    "35116667"
   ]
  },
  {
   "text": "greater area-level population density and higher levels of non-car ownership",
   "score": 12.763189315795898,
   "articlesIDs": [
    "22738416"
   ]
  },
  {
   "text": "size at birth and in early adolescence",
   "score": 12.74915885925293,
   "articlesIDs": [
    "17106438"
   ]
  },
  {
   "text": "patients with hodgkin's disease",
   "score": 12.738449096679688,
   "articlesIDs": [
    "12637473"
   ]
  },
  {
   "text": "bilateral retinoblastoma, ewing's sarcoma and soft tissue sarcoma",
   "score": 12.73702335357666,
   "articlesIDs": [
    "9663598"
   ]
  },
  {
   "text": "survivors of osteosarcoma",
   "score": 12.729639053344727,
   "articlesIDs": [
    "25116228"
   ]
  },
  {
   "text": "patients treated for sarcoma",
   "score": 12.709494590759277,
   "articlesIDs": [
    "29413281"
   ]
  },
  {
   "text": "chemotherapy-induced tumor necrosis",
   "score": 12.692289352416992,
   "articlesIDs": [
    "7989947"
   ]
  },
  {
   "text": "females in areas with lower deprivation levels",
   "score": 12.692185401916504,
   "articlesIDs": [
    "22738416"
   ]
  },
  {
   "text": "chemotherapy without radiotherapy",
   "score": 12.68740463256836,
   "articlesIDs": [
    "16152578"
   ]
  },
  {
   "text": "spayed females",
   "score": 12.68185043334961,
   "articlesIDs": [
    "36733647"
   ]
  },
  {
   "text": "doxorubicin dose per 10-mg/m increase",
   "score": 12.679906845092773,
   "articlesIDs": [
    "36875898"
   ]
  },
  {
   "text": "subjects with cyp1a1 val/val homozygous mutations",
   "score": 12.67137622833252,
   "articlesIDs": [
    "26681006"
   ]
  },
  {
   "text": "both epipodophyllotoxins and anthracyclines",
   "score": 12.666444778442383,
   "articlesIDs": [
    "12637473"
   ]
  },
  {
   "text": "increasing body weight, increasing standard weight",
   "score": 12.647700309753418,
   "articlesIDs": [
    "9691849"
   ]
  },
  {
   "text": "blacksmiths, toolmakers, machine-tool operators",
   "score": 12.620563507080078,
   "articlesIDs": [
    "16108052"
   ]
  },
  {
   "text": "children born to mothers with anemia in pregnancy",
   "score": 12.616863250732422,
   "articlesIDs": [
    "36434977"
   ]
  },
  {
   "text": "increasing age, increasing body weight",
   "score": 12.613714218139648,
   "articlesIDs": [
    "9691849"
   ]
  },
  {
   "text": "haplotype containing the rs1799793t and rs11615-t alleles",
   "score": 12.607937812805176,
   "articlesIDs": [
    "28474168"
   ]
  },
  {
   "text": "breed, bodyweight and longer leg or longer skull length",
   "score": 12.59312629699707,
   "articlesIDs": [
    "37365662"
   ]
  },
  {
   "text": "patients who had received neither radiotherapy nor chemotherapy",
   "score": 12.589258193969727,
   "articlesIDs": [
    "16152578"
   ]
  },
  {
   "text": "residence in a less affluent county",
   "score": 12.582075119018555,
   "articlesIDs": [
    "23824394"
   ]
  },
  {
   "text": "ercc2 rs1799793 polymorphism",
   "score": 12.579203605651855,
   "articlesIDs": [
    "30402838"
   ]
  },
  {
   "text": "higher birthweight",
   "score": 12.574503898620605,
   "articlesIDs": [
    "27860191"
   ]
  },
  {
   "text": "great dane (or 34.24, 95% ci 17.81-65.83) and rottweiler",
   "score": 12.565484046936035,
   "articlesIDs": [
    "37365662"
   ]
  },
  {
   "text": "advanced age, a tumor in the axial skeleton",
   "score": 12.564315795898438,
   "articlesIDs": [
    "23824394"
   ]
  },
  {
   "text": "genetic mutations in the bmp2 gene",
   "score": 12.563800811767578,
   "articlesIDs": [
    "25391427"
   ]
  },
  {
   "text": "ionizing radiation (ir)",
   "score": 12.561336517333984,
   "articlesIDs": [
    "24231354"
   ]
  },
  {
   "text": "advanced age, a tumor in the axial skeleton, a larger tumor size",
   "score": 12.556066513061523,
   "articlesIDs": [
    "23824394"
   ]
  },
  {
   "text": "sex steroid hormones",
   "score": 12.54754638671875,
   "articlesIDs": [
    "35105367"
   ]
  },
  {
   "text": "gstp1 c.313a\u003eg variant",
   "score": 12.542490005493164,
   "articlesIDs": [
    "36397425"
   ]
  },
  {
   "text": "secondary osteosarcomas",
   "score": 12.498617172241211,
   "articlesIDs": [
    "12464443"
   ]
  },
  {
   "text": "maternal migraine",
   "score": 12.497875213623047,
   "articlesIDs": [
    "37101365"
   ]
  },
  {
   "text": "individuals carrying the tt genotype of vegf +936c/t",
   "score": 12.462199211120605,
   "articlesIDs": [
    "26600515"
   ]
  },
  {
   "text": "germline mutations in the retinoblastoma tumor suppressor gene (rb1)",
   "score": 12.449806213378906,
   "articlesIDs": [
    "24231354"
   ]
  },
  {
   "text": "carrier of rs454006*c allele and rs3745406*c",
   "score": 12.447089195251465,
   "articlesIDs": [
    "25663494"
   ]
  },
  {
   "text": "tall stature, high birth weight",
   "score": 12.426177024841309,
   "articlesIDs": [
    "28338660"
   ]
  },
  {
   "text": "increasing age, increasing body weight, increasing standard weight",
   "score": 12.423040390014648,
   "articlesIDs": [
    "9691849"
   ]
  },
  {
   "text": "ercc2-rs1799793 aa+ac \u003e cc",
   "score": 12.421379089355469,
   "articlesIDs": [
    "30402838"
   ]
  },
  {
   "text": "very tall individuals (≥ 90th percentile)",
   "score": 12.419046401977539,
   "articlesIDs": [
    "21465145"
   ]
  },
  {
   "text": "receiving radiation therapy",
   "score": 12.414785385131836,
   "articlesIDs": [
    "36945154"
   ]
  },
  {
   "text": "allele-a and genotype-aa of mdm2 c.346g\u003ea genetic variant",
   "score": 12.405733108520508,
   "articlesIDs": [
    "25551700"
   ]
  },
  {
   "text": "subjects with bpa more than or equal to median value",
   "score": 12.403839111328125,
   "articlesIDs": [
    "23886186"
   ]
  },
  {
   "text": "+49\u003ea polymorphism",
   "score": 12.396810531616211,
   "articlesIDs": [
    "25000484"
   ]
  },
  {
   "text": "participants rs1799793-gt or -tt and rs4150441-ga or -aa genotype",
   "score": 12.392723083496094,
   "articlesIDs": [
    "28474168"
   ]
  },
  {
   "text": "survivors of wilms tumor, leukemia, and bone sarcoma",
   "score": 12.340837478637695,
   "articlesIDs": [
    "36444554"
   ]
  },
  {
   "text": "larger tumor size, and a residence in a less affluent county",
   "score": 12.335624694824219,
   "articlesIDs": [
    "23824394"
   ]
  },
  {
   "text": "bpa exposure",
   "score": 12.304624557495117,
   "articlesIDs": [
    "23886186"
   ]
  },
  {
   "text": "alkylating agent score (aas) [hazard ratio (hr) = 2.459, p = 0.015] and ddp",
   "score": 12.300638198852539,
   "articlesIDs": [
    "25192682"
   ]
  },
  {
   "text": "a-g haplotype",
   "score": 12.293437957763672,
   "articlesIDs": [
    "26097610"
   ]
  },
  {
   "text": "patients with advanced age",
   "score": 12.281370162963867,
   "articlesIDs": [
    "23824394"
   ]
  },
  {
   "text": "aa genotype in -308 g/a locus",
   "score": 12.278331756591797,
   "articlesIDs": [
    "26097610"
   ]
  },
  {
   "text": "rs454006 polymorphism of the prkcg gene",
   "score": 12.259744644165039,
   "articlesIDs": [
    "25252845"
   ]
  },
  {
   "text": "serum alkaline phosphatase (salp) and proximal humerus location",
   "score": 12.253517150878906,
   "articlesIDs": [
    "24054333"
   ]
  },
  {
   "text": "genotypes/alleles of c.75g[c and c.326g[a genetic polymorphisms",
   "score": 12.245959281921387,
   "articlesIDs": [
    "24078408"
   ]
  },
  {
   "text": "receiving radiation therapy, and not undergoing chemotherapy",
   "score": 12.240513801574707,
   "articlesIDs": [
    "36945154"
   ]
  },
  {
   "text": "bisphenol a (bpa)",
   "score": 12.236356735229492,
   "articlesIDs": [
    "23886186"
   ]
  },
  {
   "text": "increased serum levels of ras oncogene-related protein (p21)",
   "score": 12.227584838867188,
   "articlesIDs": [
    "1313398"
   ]
  },
  {
   "text": "cancer type",
   "score": 12.223580360412598,
   "articlesIDs": [
    "16258096"
   ]
  },
  {
   "text": "carriers with the t allele of ercc2-rs1799793",
   "score": 12.218523025512695,
   "articlesIDs": [
    "28474168"
   ]
  },
  {
   "text": "chemotherapy-induced tumor necrosis and surgical margins",
   "score": 12.214427947998047,
   "articlesIDs": [
    "7989947"
   ]
  },
  {
   "text": "rottweiler and great dane",
   "score": 12.204033851623535,
   "articlesIDs": [
    "33750475"
   ]
  },
  {
   "text": "a history of lameness condition(s) (other than osa)",
   "score": 12.202775955200195,
   "articlesIDs": [
    "36733647"
   ]
  },
  {
   "text": "mothers prescribed supplements for b12 and folate deficiency anemia",
   "score": 12.20183277130127,
   "articlesIDs": [
    "36434977"
   ]
  },
  {
   "text": "ewing sarcoma (or, 3.05), or hepatocellular carcinoma",
   "score": 12.196063995361328,
   "articlesIDs": [
    "21616236"
   ]
  },
  {
   "text": "gestational hypertension",
   "score": 12.191665649414062,
   "articlesIDs": [
    "24313390"
   ]
  },
  {
   "text": "hearing impairment",
   "score": 12.183844566345215,
   "articlesIDs": [
    "35059962"
   ]
  },
  {
   "text": "widowhood",
   "score": 12.182753562927246,
   "articlesIDs": [
    "31672959"
   ]
  },
  {
   "text": "product fabricating, assembling, and repairing",
   "score": 12.182075500488281,
   "articlesIDs": [
    "9839731"
   ]
  },
  {
   "text": "albumin less than 2.8 g/dl",
   "score": 12.180163383483887,
   "articlesIDs": [
    "30554419"
   ]
  },
  {
   "text": "proximal humerus and distal femur or proximal tibia location",
   "score": 12.179162979125977,
   "articlesIDs": [
    "24054333"
   ]
  },
  {
   "text": "heterozygous gc genotype",
   "score": 12.177900314331055,
   "articlesIDs": [
    "26810186"
   ]
  },
  {
   "text": "rs11556218 tg/gg genotypes",
   "score": 12.168841361999512,
   "articlesIDs": [
    "27703190"
   ]
  },
  {
   "text": "patients older than 40 years",
   "score": 12.168475151062012,
   "articlesIDs": [
    "31519610"
   ]
  },
  {
   "text": "latino children",
   "score": 12.163179397583008,
   "articlesIDs": [
    "16958083"
   ]
  },
  {
   "text": "-22c allele and 473a allele",
   "score": 12.152684211730957,
   "articlesIDs": [
    "22911823"
   ]
  },
  {
   "text": "patients diagnosed at an older age",
   "score": 12.151390075683594,
   "articlesIDs": [
    "36875898"
   ]
  },
  {
   "text": "low lean mass",
   "score": 12.147724151611328,
   "articlesIDs": [
    "23128330"
   ]
  },
  {
   "text": "gardeners",
   "score": 12.142230033874512,
   "articlesIDs": [
    "23036164"
   ]
  },
  {
   "text": "rottweiler dogs",
   "score": 12.130715370178223,
   "articlesIDs": [
    "28865206"
   ]
  },
  {
   "text": "anthropometric indices",
   "score": 12.12741470336914,
   "articlesIDs": [
    "35105367"
   ]
  },
  {
   "text": "histology type (ewing sarcoma",
   "score": 12.12077808380127,
   "articlesIDs": [
    "31996232"
   ]
  },
  {
   "text": "higher grade (or 1.7, p = 0.007), increasing tumor size",
   "score": 12.112058639526367,
   "articlesIDs": [
    "34018083"
   ]
  },
  {
   "text": "ewing sarcoma histology",
   "score": 12.10406494140625,
   "articlesIDs": [
    "29413281"
   ]
  },
  {
   "text": "sex steroid hormones and risk of breast and endometrial cancer; and lipids",
   "score": 12.103278160095215,
   "articlesIDs": [
    "35105367"
   ]
  },
  {
   "text": "male sex, and low lean mass",
   "score": 12.102426528930664,
   "articlesIDs": [
    "23128330"
   ]
  },
  {
   "text": "carriers of tg and gg genotypes",
   "score": 12.09011459350586,
   "articlesIDs": [
    "22205265"
   ]
  },
  {
   "text": "the presence of hernias and ewing sarcoma; high fluoride exposure",
   "score": 12.0737943649292,
   "articlesIDs": [
    "19618453"
   ]
  },
  {
   "text": "individuals with paget disease of bone, after therapeutic radiation",
   "score": 12.070647239685059,
   "articlesIDs": [
    "21437228"
   ]
  },
  {
   "text": "paternally inherited hypomorphic pathogenic variants",
   "score": 12.067425727844238,
   "articlesIDs": [
    "29662154"
   ]
  },
  {
   "text": "the travel time to the nearest comprehensive center",
   "score": 12.065779685974121,
   "articlesIDs": [
    "31212223"
   ]
  },
  {
   "text": "size between 5 and 10 mm (or, 2.78); location within the right lower lobe",
   "score": 12.051255226135254,
   "articlesIDs": [
    "21616236"
   ]
  },
  {
   "text": "carriers with the a allele of ercc3-rs4150441",
   "score": 12.04769515991211,
   "articlesIDs": [
    "28474168"
   ]
  },
  {
   "text": "circulating telomere length",
   "score": 12.033309936523438,
   "articlesIDs": [
    "35105367"
   ]
  },
  {
   "text": "increasing height",
   "score": 12.026403427124023,
   "articlesIDs": [
    "9691849"
   ]
  },
  {
   "text": "functional mdm2 t309g genetic variant",
   "score": 12.024520874023438,
   "articlesIDs": [
    "22205265"
   ]
  },
  {
   "text": "long-term survivors of chondrosarcoma",
   "score": 12.024486541748047,
   "articlesIDs": [
    "26883654"
   ]
  },
  {
   "text": "young age at diagnosis, male sex, and low lean mass",
   "score": 12.023187637329102,
   "articlesIDs": [
    "23128330"
   ]
  },
  {
   "text": "absence of the gstm1 homozygous genotype",
   "score": 11.994912147521973,
   "articlesIDs": [
    "26681006"
   ]
  },
  {
   "text": "parental breast cancer",
   "score": 11.993408203125,
   "articlesIDs": [
    "11809347"
   ]
  },
  {
   "text": "male patients, primary tumor site, tumor type and size",
   "score": 11.99294662475586,
   "articlesIDs": [
    "33553341"
   ]
  },
  {
   "text": "month of birth (may through july versus other months of birth)",
   "score": 11.987829208374023,
   "articlesIDs": [
    "7618957"
   ]
  },
  {
   "text": "increase of 500 gram of birth weight",
   "score": 11.985162734985352,
   "articlesIDs": [
    "26371026"
   ]
  },
  {
   "text": "race other class, receiving radiation therapy",
   "score": 11.959446907043457,
   "articlesIDs": [
    "36945154"
   ]
  },
  {
   "text": "sex, tumor site, type and size",
   "score": 11.95771598815918,
   "articlesIDs": [
    "33553341"
   ]
  },
  {
   "text": "elevated serum levels of pdgf-related protein",
   "score": 11.938429832458496,
   "articlesIDs": [
    "1313398"
   ]
  },
  {
   "text": "subjects diagnosed before attainment of puberty (male ≤ 16 y, female ≤ 14 y)",
   "score": 11.932186126708984,
   "articlesIDs": [
    "23128330"
   ]
  },
  {
   "text": "older age (years)",
   "score": 11.917956352233887,
   "articlesIDs": [
    "24054333"
   ]
  },
  {
   "text": "ewing sarcoma histology (hr 9.95, p \u003c .0001) and osteosarcoma histology",
   "score": 11.891180038452148,
   "articlesIDs": [
    "29413281"
   ]
  },
  {
   "text": "increasing comorbidity burden",
   "score": 11.888050079345703,
   "articlesIDs": [
    "34018083"
   ]
  },
  {
   "text": "high birth weight and certain inherited cancer predisposition syndromes",
   "score": 11.866521835327148,
   "articlesIDs": [
    "28338660"
   ]
  },
  {
   "text": "associated complications, and cancer type",
   "score": 11.866369247436523,
   "articlesIDs": [
    "16258096"
   ]
  },
  {
   "text": "osteosarcoma amplified 9 (os9)",
   "score": 11.853142738342285,
   "articlesIDs": [
    "22936702"
   ]
  },
  {
   "text": "original pet positive study",
   "score": 11.852982521057129,
   "articlesIDs": [
    "23701776"
   ]
  },
  {
   "text": "original pet positive study (p\u003c0.05) and patients with osteosarcoma",
   "score": 11.847493171691895,
   "articlesIDs": [
    "23701776"
   ]
  },
  {
   "text": "polycystic ovary syndrome (pcos)",
   "score": 11.845787048339844,
   "articlesIDs": [
    "22723319"
   ]
  },
  {
   "text": "patients with advanced age, a tumor in the axial skeleton",
   "score": 11.840457916259766,
   "articlesIDs": [
    "23824394"
   ]
  },
  {
   "text": "variant genotypes of rs4938723 tc/cc",
   "score": 11.834810256958008,
   "articlesIDs": [
    "24063968"
   ]
  },
  {
   "text": "bone tissue exposed to 1-4 gy",
   "score": 11.815285682678223,
   "articlesIDs": [
    "37235821"
   ]
  },
  {
   "text": "rs3178250 tt genotype",
   "score": 11.8130464553833,
   "articlesIDs": [
    "25391427"
   ]
  },
  {
   "text": "receipt of radiation therapy",
   "score": 11.801424026489258,
   "articlesIDs": [
    "29413281"
   ]
  },
  {
   "text": "patients with high-grade osteosarcoma",
   "score": 11.791990280151367,
   "articlesIDs": [
    "26002013"
   ]
  },
  {
   "text": "exposure radiotherapy",
   "score": 11.78952693939209,
   "articlesIDs": [
    "36945154"
   ]
  },
  {
   "text": "combined radiotherapy and chemotherapy",
   "score": 11.755850791931152,
   "articlesIDs": [
    "16152578"
   ]
  },
  {
   "text": "patients who received more than 6 g/m(2) of epipodophyllotoxins",
   "score": 11.753032684326172,
   "articlesIDs": [
    "12637473"
   ]
  },
  {
   "text": "low body mass index",
   "score": 11.749277114868164,
   "articlesIDs": [
    "32764814"
   ]
  },
  {
   "text": "aya patients",
   "score": 11.745296478271484,
   "articlesIDs": [
    "30121085"
   ]
  },
  {
   "text": "t/c variant of rs454006 located in the intron 3 region of prkcg gene",
   "score": 11.742432594299316,
   "articlesIDs": [
    "25663494"
   ]
  },
  {
   "text": "atomic bomb radiation",
   "score": 11.740889549255371,
   "articlesIDs": [
    "8176838"
   ]
  },
  {
   "text": "peripheral location (odds ratio [or], 9.1); size between 5 and 10 mm",
   "score": 11.729328155517578,
   "articlesIDs": [
    "21616236"
   ]
  },
  {
   "text": "genetic propensity for taller adult and childhood height attainments",
   "score": 11.722103118896484,
   "articlesIDs": [
    "30311632"
   ]
  },
  {
   "text": "haplotype containing the rs1799793-t and rs11615-t alleles",
   "score": 11.711877822875977,
   "articlesIDs": [
    "28474168"
   ]
  },
  {
   "text": "childhood cancer survivors",
   "score": 11.703407287597656,
   "articlesIDs": [
    "30216123",
    "34810210",
    "37182536"
   ]
  },
  {
   "text": "age, gender, income, education",
   "score": 11.693643569946289,
   "articlesIDs": [
    "31519610"
   ]
  },
  {
   "text": "insurance status, tumor location and comorbidity burden",
   "score": 11.685075759887695,
   "articlesIDs": [
    "34018083"
   ]
  },
  {
   "text": "residence in a population of less than 9,000",
   "score": 11.681400299072266,
   "articlesIDs": [
    "7618957"
   ]
  },
  {
   "text": "earlier adolescent growth period, and earlier attainment of final height",
   "score": 11.672466278076172,
   "articlesIDs": [
    "17106438"
   ]
  },
  {
   "text": "recurrence (p \u003c 0.0001), lung metastasis time",
   "score": 11.668495178222656,
   "articlesIDs": [
    "30989587"
   ]
  },
  {
   "text": "having a parent with osteosarcoma",
   "score": 11.647441864013672,
   "articlesIDs": [
    "28331626"
   ]
  },
  {
   "text": "patients with g-a and a-a haplotypes",
   "score": 11.644796371459961,
   "articlesIDs": [
    "26097610"
   ]
  },
  {
   "text": "her-2/neu expression",
   "score": 11.619983673095703,
   "articlesIDs": [
    "12544770"
   ]
  },
  {
   "text": "distant disease (hr 2.67, p=.004), male gender",
   "score": 11.612508773803711,
   "articlesIDs": [
    "29413281"
   ]
  },
  {
   "text": "germline p53 mutations",
   "score": 11.582664489746094,
   "articlesIDs": [
    "8308926"
   ]
  },
  {
   "text": "bpa level and the -22 g/c polymorphism",
   "score": 11.577713966369629,
   "articlesIDs": [
    "23886186"
   ]
  },
  {
   "text": "genotypes/alleles of c.44c\u003et and c.1002t\u003ec",
   "score": 11.569820404052734,
   "articlesIDs": [
    "23933591"
   ]
  },
  {
   "text": "higher maternal education",
   "score": 11.558286666870117,
   "articlesIDs": [
    "24313390"
   ]
  },
  {
   "text": "increase in bw of 1 kg",
   "score": 11.55770492553711,
   "articlesIDs": [
    "25732913"
   ]
  },
  {
   "text": "the t allele of ercc2-rs1799793 and the a allele of ercc3-rs4150441",
   "score": 11.546571731567383,
   "articlesIDs": [
    "28474168"
   ]
  },
  {
   "text": "regional node involvement",
   "score": 11.527169227600098,
   "articlesIDs": [
    "23867123"
   ]
  },
  {
   "text": "hiv), prior radiation exposure, and genetic syndromes",
   "score": 11.520567893981934,
   "articlesIDs": [
    "19460580"
   ]
  },
  {
   "text": "-22g/c and 473g/a polymorphisms",
   "score": 11.518775939941406,
   "articlesIDs": [
    "22911823"
   ]
  },
  {
   "text": "rural status",
   "score": 11.510643005371094,
   "articlesIDs": [
    "31212223"
   ]
  },
  {
   "text": "children's diseases in their history, which increased the risk were measles",
   "score": 11.509016990661621,
   "articlesIDs": [
    "15225895"
   ]
  },
  {
   "text": "amputation due to malignant bone tumors",
   "score": 11.499822616577148,
   "articlesIDs": [
    "35116667"
   ]
  },
  {
   "text": "ga and aa genotypes of rs3217992 in cdkn2a",
   "score": 11.487951278686523,
   "articlesIDs": [
    "30774116"
   ]
  },
  {
   "text": "higher grade (or = 5.197, 95% ci 3.328 to 8.117), histology type",
   "score": 11.48573112487793,
   "articlesIDs": [
    "31996232"
   ]
  },
  {
   "text": "height at diagnosis and birth-weight",
   "score": 11.484522819519043,
   "articlesIDs": [
    "21465145"
   ]
  },
  {
   "text": "receipt of radiation therapy (hazard ratio [hr] 1.67, p=.02), distant disease",
   "score": 11.462247848510742,
   "articlesIDs": [
    "29413281"
   ]
  },
  {
   "text": "a genetic propensity for taller adult and childhood height attainments",
   "score": 11.461055755615234,
   "articlesIDs": [
    "30311632"
   ]
  },
  {
   "text": "null gstti",
   "score": 11.44266128540039,
   "articlesIDs": [
    "22471480"
   ]
  },
  {
   "text": "mumps",
   "score": 11.433195114135742,
   "articlesIDs": [
    "15225895"
   ]
  },
  {
   "text": "history of retinoblastoma as the primary cancer",
   "score": 11.428470611572266,
   "articlesIDs": [
    "30053029"
   ]
  },
  {
   "text": "age group",
   "score": 11.395816802978516,
   "articlesIDs": [
    "16258096"
   ]
  },
  {
   "text": "low-dose etoposide",
   "score": 11.394685745239258,
   "articlesIDs": [
    "8202048"
   ]
  },
  {
   "text": "rhodesian ridgeback",
   "score": 11.388130187988281,
   "articlesIDs": [
    "33750475"
   ]
  },
  {
   "text": "mdm2 snp309",
   "score": 11.380578994750977,
   "articlesIDs": [
    "19451596"
   ]
  },
  {
   "text": "high levels of hba1c",
   "score": 11.376758575439453,
   "articlesIDs": [
    "32764814"
   ]
  },
  {
   "text": "older age at diagnosis, race other class, receiving radiation therapy",
   "score": 11.363990783691406,
   "articlesIDs": [
    "36945154"
   ]
  },
  {
   "text": "the -22c allele and 473a allele",
   "score": 11.351122856140137,
   "articlesIDs": [
    "22911823"
   ]
  },
  {
   "text": "functional genetic polymorphisms in cdkn2a/b",
   "score": 11.338846206665039,
   "articlesIDs": [
    "30774116"
   ]
  },
  {
   "text": "secondary osteosarcomas occurring within a field of radiation",
   "score": 11.338706970214844,
   "articlesIDs": [
    "12464443"
   ]
  },
  {
   "text": "increasing comorbidity burden (or 6.6, p = 0.001), higher grade",
   "score": 11.302848815917969,
   "articlesIDs": [
    "34018083"
   ]
  },
  {
   "text": "earlier period of diagnosis",
   "score": 11.296319007873535,
   "articlesIDs": [
    "35116667"
   ]
  },
  {
   "text": "age over 65 years",
   "score": 11.27578067779541,
   "articlesIDs": [
    "36945154"
   ]
  },
  {
   "text": "elevated serum pdgf levels",
   "score": 11.27322006225586,
   "articlesIDs": [
    "1313398"
   ]
  },
  {
   "text": "patients who were diagnosed with bc",
   "score": 11.267402648925781,
   "articlesIDs": [
    "29019328"
   ]
  },
  {
   "text": "accumulation of ≥4 grade 3-4 chronic conditions",
   "score": 11.265981674194336,
   "articlesIDs": [
    "32499311"
   ]
  },
  {
   "text": "heterozygous ct genotype",
   "score": 11.264202117919922,
   "articlesIDs": [
    "26754027"
   ]
  },
  {
   "text": "age group, year of discharge",
   "score": 11.258233070373535,
   "articlesIDs": [
    "16258096"
   ]
  },
  {
   "text": "age group, year of discharge, associated complications, and cancer type",
   "score": 11.249617576599121,
   "articlesIDs": [
    "16258096"
   ]
  },
  {
   "text": "localization in the lower limbs (p = 0.0007), curettage",
   "score": 11.232015609741211,
   "articlesIDs": [
    "30989587"
   ]
  },
  {
   "text": "local irradiation of the primary tumor",
   "score": 11.225911140441895,
   "articlesIDs": [
    "30989587"
   ]
  },
  {
   "text": "toolmakers, machine-tool operators (or = 2.14, 95% ci 1.08-4.26), woodworkers",
   "score": 11.208266258239746,
   "articlesIDs": [
    "16108052"
   ]
  },
  {
   "text": "mdm2 rs2279744 polymorphism",
   "score": 11.207956314086914,
   "articlesIDs": [
    "24122202"
   ]
  },
  {
   "text": "the +49g\u003ea polymorphism",
   "score": 11.200528144836426,
   "articlesIDs": [
    "25000484"
   ]
  },
  {
   "text": "history of radiation",
   "score": 11.193973541259766,
   "articlesIDs": [
    "32990990"
   ]
  },
  {
   "text": "patients living in low socioeconomic counties",
   "score": 11.19382095336914,
   "articlesIDs": [
    "26002013"
   ]
  },
  {
   "text": "distant metastasis",
   "score": 11.189345359802246,
   "articlesIDs": [
    "33553341"
   ]
  },
  {
   "text": "dogs over 40 kg",
   "score": 11.187999725341797,
   "articlesIDs": [
    "33750475"
   ]
  },
  {
   "text": "metastatic disease at presentation (or 8.5, p \u003c 0.001), and amputation",
   "score": 11.162506103515625,
   "articlesIDs": [
    "34018083"
   ]
  },
  {
   "text": "the tt genotype of vegf +936c/t genetic variants",
   "score": 11.154948234558105,
   "articlesIDs": [
    "26600515"
   ]
  },
  {
   "text": "the aa genotype of -308 g/a locus of tnf-α gene",
   "score": 11.13920783996582,
   "articlesIDs": [
    "26097610"
   ]
  },
  {
   "text": "aa, ag, and gg types of gstp1 c.313a\u003eg variant",
   "score": 11.125435829162598,
   "articlesIDs": [
    "36397425"
   ]
  },
  {
   "text": "cancer type, and associated complications",
   "score": 11.11578369140625,
   "articlesIDs": [
    "16258096"
   ]
  },
  {
   "text": "race, age group, year of discharge",
   "score": 11.115558624267578,
   "articlesIDs": [
    "16258096"
   ]
  },
  {
   "text": "age at diagnosis (hr: 1.23; 95% ci: 1.06-1.43) per 5-year increase",
   "score": 11.114982604980469,
   "articlesIDs": [
    "36875898"
   ]
  },
  {
   "text": "pgp positivity",
   "score": 11.111322402954102,
   "articlesIDs": [
    "12879476"
   ]
  },
  {
   "text": "gstt1 polymorphism among asians",
   "score": 11.110210418701172,
   "articlesIDs": [
    "30909663"
   ]
  },
  {
   "text": "the rottweiler and great dane",
   "score": 11.108942031860352,
   "articlesIDs": [
    "33750475"
   ]
  },
  {
   "text": "metastasis and rural status",
   "score": 11.099661827087402,
   "articlesIDs": [
    "31212223"
   ]
  },
  {
   "text": "haplotype block in igf2r",
   "score": 11.097481727600098,
   "articlesIDs": [
    "17684144"
   ]
  },
  {
   "text": "survivors of heritable retinoblastoma",
   "score": 11.081611633300781,
   "articlesIDs": [
    "19704040"
   ]
  },
  {
   "text": "polymorphisms in pre-mirnas at 14q32 mirna cluster",
   "score": 11.066150665283203,
   "articlesIDs": [
    "30337581"
   ]
  },
  {
   "text": "an increase of 500 gram of birth weight",
   "score": 11.063507080078125,
   "articlesIDs": [
    "26371026"
   ]
  },
  {
   "text": "those with a hispanic origin",
   "score": 11.055968284606934,
   "articlesIDs": [
    "31006987"
   ]
  },
  {
   "text": "difficulties in school, indicative of emotional disturbances",
   "score": 11.03487777709961,
   "articlesIDs": [
    "15225895"
   ]
  },
  {
   "text": "prevalence of the -22c allele and 473a allele",
   "score": 11.017314910888672,
   "articlesIDs": [
    "22911823"
   ]
  },
  {
   "text": "patients with the lowest socioeconomic status",
   "score": 10.989029884338379,
   "articlesIDs": [
    "26002013"
   ]
  },
  {
   "text": "survivors of aya bone and soft tissue sarcoma",
   "score": 10.988458633422852,
   "articlesIDs": [
    "24752471"
   ]
  },
  {
   "text": "poor health status",
   "score": 10.973177909851074,
   "articlesIDs": [
    "25989269"
   ]
  },
  {
   "text": "higher cumulative dose of doxorubicin",
   "score": 10.959700584411621,
   "articlesIDs": [
    "7760889"
   ]
  },
  {
   "text": "breeds iw and lb",
   "score": 10.948686599731445,
   "articlesIDs": [
    "22210997"
   ]
  },
  {
   "text": "each standard deviation increase in the polygenic score for childhood height",
   "score": 10.948592185974121,
   "articlesIDs": [
    "30311632"
   ]
  },
  {
   "text": "in children born to mothers with anemia in pregnancy",
   "score": 10.932331085205078,
   "articlesIDs": [
    "36434977"
   ]
  },
  {
   "text": "female sex and a higher cumulative dose of doxorubicin",
   "score": 10.924321174621582,
   "articlesIDs": [
    "7760889"
   ]
  },
  {
   "text": "osteosarcoma and ewing sarcoma survivors",
   "score": 10.919761657714844,
   "articlesIDs": [
    "32499311"
   ]
  },
  {
   "text": "those treated with teriparatide",
   "score": 10.915179252624512,
   "articlesIDs": [
    "32894794"
   ]
  },
  {
   "text": "increased health-care usage",
   "score": 10.910514831542969,
   "articlesIDs": [
    "25989269"
   ]
  },
  {
   "text": "radiation exposure from radiotherapy",
   "score": 10.903155326843262,
   "articlesIDs": [
    "23036164"
   ]
  },
  {
   "text": "each decade of life older than the first decade",
   "score": 10.896180152893066,
   "articlesIDs": [
    "7989947"
   ]
  },
  {
   "text": "every 1-cm increase in tumor size",
   "score": 10.88852310180664,
   "articlesIDs": [
    "31006987"
   ]
  },
  {
   "text": "those with a black, non-hispanic race",
   "score": 10.876046180725098,
   "articlesIDs": [
    "31006987"
   ]
  },
  {
   "text": "chemotherapy response",
   "score": 10.87418270111084,
   "articlesIDs": [
    "7989947"
   ]
  },
  {
   "text": "survivors of aya sarcoma",
   "score": 10.848737716674805,
   "articlesIDs": [
    "24752471"
   ]
  },
  {
   "text": "rs454006 polymorphisms of the prkcg gene include the cc, ct, and tt genotypes",
   "score": 10.835504531860352,
   "articlesIDs": [
    "25252845"
   ]
  },
  {
   "text": "increasing height than increasing weight",
   "score": 10.823505401611328,
   "articlesIDs": [
    "9691849"
   ]
  },
  {
   "text": "plasma mir-34b",
   "score": 10.821393966674805,
   "articlesIDs": [
    "24063968"
   ]
  },
  {
   "text": "male lb that developed primary bone cancer later in life",
   "score": 10.819156646728516,
   "articlesIDs": [
    "25732913"
   ]
  },
  {
   "text": "history of radiation and 4% for history of paget's disease of bone",
   "score": 10.81893539428711,
   "articlesIDs": [
    "32990990"
   ]
  },
  {
   "text": "an allele of the snp rs3217992",
   "score": 10.817832946777344,
   "articlesIDs": [
    "30774116"
   ]
  },
  {
   "text": "bacterial cystitis",
   "score": 10.816946983337402,
   "articlesIDs": [
    "26595882"
   ]
  },
  {
   "text": "polymorphisms in gstm1 and gstti",
   "score": 10.809410095214844,
   "articlesIDs": [
    "22471480"
   ]
  },
  {
   "text": "the t/c variant of rs454006 located in the intron 3 region of prkcg gene",
   "score": 10.799668312072754,
   "articlesIDs": [
    "25663494"
   ]
  },
  {
   "text": "subjects carrying the tp53 arg72pro polymorphism",
   "score": 10.796612739562988,
   "articlesIDs": [
    "19451596"
   ]
  },
  {
   "text": "comorbid impairment (i.e., ≥ 2 neurocognitive domains)",
   "score": 10.789571762084961,
   "articlesIDs": [
    "35059962"
   ]
  },
  {
   "text": "increased health-care usage and poor health status",
   "score": 10.788373947143555,
   "articlesIDs": [
    "25989269"
   ]
  },
  {
   "text": "family history of cancer among the first or second-degree relatives",
   "score": 10.783326148986816,
   "articlesIDs": [
    "22340225"
   ]
  },
  {
   "text": "bone cancers",
   "score": 10.779884338378906,
   "articlesIDs": [
    "11809347"
   ]
  },
  {
   "text": "patients received chest irradiation at young age",
   "score": 10.777116775512695,
   "articlesIDs": [
    "29019328"
   ]
  },
  {
   "text": "tplo site osa",
   "score": 10.772150039672852,
   "articlesIDs": [
    "25079048"
   ]
  },
  {
   "text": "patients who had progressive pleural disease after thoracotomy",
   "score": 10.770297050476074,
   "articlesIDs": [
    "11267963"
   ]
  },
  {
   "text": "bone development during pubertal growth spurts",
   "score": 10.768407821655273,
   "articlesIDs": [
    "23036164"
   ]
  },
  {
   "text": "tgfbr1*6a, a dominant polymorphism of tgfbr1",
   "score": 10.742941856384277,
   "articlesIDs": [
    "20429896"
   ]
  },
  {
   "text": "marker rflps",
   "score": 10.740133285522461,
   "articlesIDs": [
    "2892131"
   ]
  },
  {
   "text": "neoadjuvant radiotherapy",
   "score": 10.735824584960938,
   "articlesIDs": [
    "30554419"
   ]
  },
  {
   "text": "ionising radiation",
   "score": 10.689962387084961,
   "articlesIDs": [
    "10226399"
   ]
  },
  {
   "text": "mdm2 polymorphism t309g",
   "score": 10.680757522583008,
   "articlesIDs": [
    "19451596"
   ]
  },
  {
   "text": "the presence of metastasis",
   "score": 10.668843269348145,
   "articlesIDs": [
    "31212223"
   ]
  },
  {
   "text": "older patients",
   "score": 10.658544540405273,
   "articlesIDs": [
    "7989947"
   ]
  },
  {
   "text": "the rs3745406 t/c variant",
   "score": 10.647762298583984,
   "articlesIDs": [
    "25663494"
   ]
  },
  {
   "text": "among children with fathers in social sciences",
   "score": 10.637933731079102,
   "articlesIDs": [
    "9839731"
   ]
  },
  {
   "text": "presence of tc and cc genotypes of rs6218",
   "score": 10.637518882751465,
   "articlesIDs": [
    "29232358"
   ]
  },
  {
   "text": "avascular necrosis (avn)",
   "score": 10.636171340942383,
   "articlesIDs": [
    "35954639"
   ]
  },
  {
   "text": "male cases, however, appeared to have an earlier adolescent growth period",
   "score": 10.632920265197754,
   "articlesIDs": [
    "17106438"
   ]
  },
  {
   "text": "lower serum il-27p28 levels",
   "score": 10.631522178649902,
   "articlesIDs": [
    "25170932"
   ]
  },
  {
   "text": "location in the proximal femur, tibia, and humerus",
   "score": 10.624921798706055,
   "articlesIDs": [
    "27145235"
   ]
  },
  {
   "text": "multiple gestation was",
   "score": 10.608976364135742,
   "articlesIDs": [
    "35929579"
   ]
  },
  {
   "text": "homozygosity and heterozygosity of the tgfbr1*6a allele",
   "score": 10.596010208129883,
   "articlesIDs": [
    "20429896"
   ]
  },
  {
   "text": "gstt1 and gstm3 polymorphisms",
   "score": 10.589925765991211,
   "articlesIDs": [
    "24689813"
   ]
  },
  {
   "text": "the alkylating agent score (aas)",
   "score": 10.55610466003418,
   "articlesIDs": [
    "25192682"
   ]
  },
  {
   "text": "children younger than 5 years",
   "score": 10.548828125,
   "articlesIDs": [
    "15519518"
   ]
  },
  {
   "text": "alkylating agent chemotherapy",
   "score": 10.53243637084961,
   "articlesIDs": [
    "1729013"
   ]
  },
  {
   "text": "the gstt1 polymorphism",
   "score": 10.53016471862793,
   "articlesIDs": [
    "22471480"
   ]
  },
  {
   "text": "an increase in bw of 1 kg",
   "score": 10.514172554016113,
   "articlesIDs": [
    "25732913"
   ]
  },
  {
   "text": "older age, black and earlier period of diagnosis",
   "score": 10.508081436157227,
   "articlesIDs": [
    "35116667"
   ]
  },
  {
   "text": "retinoblastoma, bone sarcoma, and soft tissue sarcoma",
   "score": 10.503626823425293,
   "articlesIDs": [
    "28954302"
   ]
  },
  {
   "text": "the +49\u003ea polymorphism",
   "score": 10.498462677001953,
   "articlesIDs": [
    "25000484"
   ]
  },
  {
   "text": "the ercc2 rs1799793 polymorphism",
   "score": 10.497556686401367,
   "articlesIDs": [
    "30402838"
   ]
  },
  {
   "text": "tumor enlargement, inadequate margin, and local recurrence",
   "score": 10.471452713012695,
   "articlesIDs": [
    "22009712"
   ]
  },
  {
   "text": "patients with an income of $38,000-47,999",
   "score": 10.463363647460938,
   "articlesIDs": [
    "31519610"
   ]
  },
  {
   "text": "adriamycin and radiation",
   "score": 10.454283714294434,
   "articlesIDs": [
    "98227"
   ]
  },
  {
   "text": "bone cancer patients",
   "score": 10.449106216430664,
   "articlesIDs": [
    "16788847"
   ]
  },
  {
   "text": "questionnaire",
   "score": 10.448237419128418,
   "articlesIDs": [
    "30689685"
   ]
  },
  {
   "text": "reduced rb1 expression from a common promoter variant",
   "score": 10.445333480834961,
   "articlesIDs": [
    "25092376"
   ]
  },
  {
   "text": "genetic polymorphisms of tcf21",
   "score": 10.440185546875,
   "articlesIDs": [
    "28663539"
   ]
  },
  {
   "text": "measles (rr = 1.56, not significant) and mumps",
   "score": 10.419188499450684,
   "articlesIDs": [
    "15225895"
   ]
  },
  {
   "text": "tgfbr1*6a, a dominant polymorphism of tgfbr1,",
   "score": 10.40816879272461,
   "articlesIDs": [
    "20429896"
   ]
  },
  {
   "text": "survivors of hl",
   "score": 10.384137153625488,
   "articlesIDs": [
    "36444554"
   ]
  },
  {
   "text": "successful treatment of ewing's sarcoma",
   "score": 10.359970092773438,
   "articlesIDs": [
    "1729013"
   ]
  },
  {
   "text": "polymorphisms in gstt1 or gstm3 (aa",
   "score": 10.358674049377441,
   "articlesIDs": [
    "24689813"
   ]
  },
  {
   "text": "breeds selected for long legs/large body mass",
   "score": 10.353719711303711,
   "articlesIDs": [
    "33750475"
   ]
  },
  {
   "text": "exposure of bone tissue to cumulative radiation doses of 1-9 gy",
   "score": 10.345535278320312,
   "articlesIDs": [
    "37235821"
   ]
  },
  {
   "text": "patients treated with teriparatide",
   "score": 10.338624954223633,
   "articlesIDs": [
    "32990990"
   ]
  },
  {
   "text": "the heterozygous ct genotype",
   "score": 10.333711624145508,
   "articlesIDs": [
    "26754027"
   ]
  },
  {
   "text": "radiotherapy in ages below 55",
   "score": 10.332450866699219,
   "articlesIDs": [
    "16152578"
   ]
  },
  {
   "text": "allele-c/genotype-cc of c.75g[c and allele-a/genotype-aa of c.326g[a",
   "score": 10.331542015075684,
   "articlesIDs": [
    "24078408"
   ]
  },
  {
   "text": "survivors of osteosarcoma and ewing sarcoma",
   "score": 10.330936431884766,
   "articlesIDs": [
    "32499311"
   ]
  },
  {
   "text": "a common rb1 allele derived from the balb/chenhg strain",
   "score": 10.317916870117188,
   "articlesIDs": [
    "25092376"
   ]
  },
  {
   "text": "curettage (p = 0.0005), and local irradiation of the primary tumor",
   "score": 10.312692642211914,
   "articlesIDs": [
    "30989587"
   ]
  },
  {
   "text": "adolescent and young adult (aya)",
   "score": 10.306478500366211,
   "articlesIDs": [
    "30121085"
   ]
  },
  {
   "text": "rs6218 tc and cc genotypes",
   "score": 10.305950164794922,
   "articlesIDs": [
    "29232358"
   ]
  },
  {
   "text": "the rs454006 polymorphism of the prkcg gene",
   "score": 10.29472541809082,
   "articlesIDs": [
    "25252845"
   ]
  },
  {
   "text": "procarbazine, ifosfamide, and cyclophosphamide",
   "score": 10.294072151184082,
   "articlesIDs": [
    "37235821"
   ]
  },
  {
   "text": "null gstt1 genotype",
   "score": 10.286371231079102,
   "articlesIDs": [
    "22471480"
   ]
  },
  {
   "text": "marker rflps with the mutation predisposing to retinoblastoma",
   "score": 10.267524719238281,
   "articlesIDs": [
    "2892131"
   ]
  },
  {
   "text": "young age at the time of tha",
   "score": 10.265121459960938,
   "articlesIDs": [
    "10871224"
   ]
  },
  {
   "text": "alkylating agents exceeding 10,000 mg/m",
   "score": 10.244733810424805,
   "articlesIDs": [
    "37235821"
   ]
  },
  {
   "text": "higher bw during the growth period",
   "score": 10.242843627929688,
   "articlesIDs": [
    "25732913"
   ]
  },
  {
   "text": "neurological conditions",
   "score": 10.234806060791016,
   "articlesIDs": [
    "35059962"
   ]
  },
  {
   "text": "age, gender, income, education, stage at diagnosis, radiation therapy",
   "score": 10.222986221313477,
   "articlesIDs": [
    "31519610"
   ]
  },
  {
   "text": "higher cumulative cyclophosphamide dose",
   "score": 10.20277214050293,
   "articlesIDs": [
    "17570705"
   ]
  },
  {
   "text": "parental kidney cancers (sir 6.8). bone cancers",
   "score": 10.188746452331543,
   "articlesIDs": [
    "11809347"
   ]
  },
  {
   "text": "fancc",
   "score": 10.178014755249023,
   "articlesIDs": [
    "35512711"
   ]
  },
  {
   "text": "patients who received radiation therapy",
   "score": 10.175731658935547,
   "articlesIDs": [
    "31519610"
   ]
  },
  {
   "text": "patients with a allele",
   "score": 10.168749809265137,
   "articlesIDs": [
    "26097610"
   ]
  },
  {
   "text": "the il-6 -174 g/c genotype",
   "score": 10.168564796447754,
   "articlesIDs": [
    "26810186"
   ]
  },
  {
   "text": "having bacterial cystitis",
   "score": 10.127565383911133,
   "articlesIDs": [
    "26595882"
   ]
  },
  {
   "text": "the heterozygous gc genotype",
   "score": 10.113415718078613,
   "articlesIDs": [
    "26810186"
   ]
  },
  {
   "text": "syndromic forms of osteosarcoma (os)",
   "score": 10.106513977050781,
   "articlesIDs": [
    "25092376"
   ]
  },
  {
   "text": "kidney dysfunction and high levels of hba1c",
   "score": 10.098930358886719,
   "articlesIDs": [
    "32764814"
   ]
  },
  {
   "text": "carriers of the g-t-t-g and a-t-t-g haplotypes",
   "score": 10.077377319335938,
   "articlesIDs": [
    "25391427"
   ]
  },
  {
   "text": "survivors of hl (sir, 7.1; 95% ci, 5.1-10.0), wilms tumor",
   "score": 10.07537841796875,
   "articlesIDs": [
    "36444554"
   ]
  },
  {
   "text": "the presence of tc and cc genotypes of rs6218",
   "score": 10.072208404541016,
   "articlesIDs": [
    "29232358"
   ]
  },
  {
   "text": "after therapeutic radiation, and in certain cancer predisposition syndromes",
   "score": 10.071826934814453,
   "articlesIDs": [
    "21437228"
   ]
  },
  {
   "text": "fluoride in drinking water",
   "score": 10.068532943725586,
   "articlesIDs": [
    "24425828"
   ]
  },
  {
   "text": "among patients who had received neither radiotherapy nor chemotherapy",
   "score": 10.06241226196289,
   "articlesIDs": [
    "16152578"
   ]
  },
  {
   "text": "5-year increase, doxorubicin dose per 10-mg/m increase",
   "score": 10.044861793518066,
   "articlesIDs": [
    "36875898"
   ]
  },
  {
   "text": "male sex, axial location, and size≥10cm",
   "score": 10.043643951416016,
   "articlesIDs": [
    "26002013"
   ]
  },
  {
   "text": "polymorphisms in gstt1 or gstm3 (aa versus bb)",
   "score": 10.043474197387695,
   "articlesIDs": [
    "24689813"
   ]
  },
  {
   "text": "chemotherapy-sensitive",
   "score": 10.029101371765137,
   "articlesIDs": [
    "24752471"
   ]
  },
  {
   "text": "tumor enlargement after chemotherapy",
   "score": 10.026134490966797,
   "articlesIDs": [
    "22009712"
   ]
  },
  {
   "text": "a history of retinoblastoma as the primary cancer",
   "score": 10.019434928894043,
   "articlesIDs": [
    "30053029"
   ]
  },
  {
   "text": "bacterial cystitis and appearing again in the vmdb with ubtcc",
   "score": 10.002381324768066,
   "articlesIDs": [
    "26595882"
   ]
  },
  {
   "text": "height one year before diagnosis",
   "score": 9.993265151977539,
   "articlesIDs": [
    "9169161"
   ]
  },
  {
   "text": "married, separated/divorced, widowed, and never-married subjects",
   "score": 9.982023239135742,
   "articlesIDs": [
    "31672959"
   ]
  },
  {
   "text": "genotype cc of il-6 -174 g/c",
   "score": 9.963253021240234,
   "articlesIDs": [
    "26810186"
   ]
  },
  {
   "text": "the ercc2-rs1799793 aa+ac \u003e cc",
   "score": 9.961847305297852,
   "articlesIDs": [
    "30402838"
   ]
  },
  {
   "text": "black race",
   "score": 9.957687377929688,
   "articlesIDs": [
    "19224548"
   ]
  },
  {
   "text": "age (p = 0.049) and neoadjuvant radiotherapy",
   "score": 9.951129913330078,
   "articlesIDs": [
    "30554419"
   ]
  },
  {
   "text": "low-dose etoposide in addition to that assumed for cyclophosphamide",
   "score": 9.948062896728516,
   "articlesIDs": [
    "8202048"
   ]
  },
  {
   "text": "black race, older age",
   "score": 9.941499710083008,
   "articlesIDs": [
    "19224548"
   ]
  },
  {
   "text": "pediatric solid tumor",
   "score": 9.939685821533203,
   "articlesIDs": [
    "29869758"
   ]
  },
  {
   "text": ", multiple gestation",
   "score": 9.93081283569336,
   "articlesIDs": [
    "35929579"
   ]
  },
  {
   "text": "with the gstt1 polymorphism",
   "score": 9.928640365600586,
   "articlesIDs": [
    "22471480"
   ]
  },
  {
   "text": "bone sarcoma survivors",
   "score": 9.925253868103027,
   "articlesIDs": [
    "25989269"
   ]
  },
  {
   "text": "rs8103851",
   "score": 9.899774551391602,
   "articlesIDs": [
    "25252845"
   ]
  },
  {
   "text": "vte and mb",
   "score": 9.873472213745117,
   "articlesIDs": [
    "36435048"
   ]
  },
  {
   "text": "proximal tumor location",
   "score": 9.87343978881836,
   "articlesIDs": [
    "27145235"
   ]
  },
  {
   "text": ". taller than average (51st - 89th percentile)",
   "score": 9.871417045593262,
   "articlesIDs": [
    "21465145"
   ]
  },
  {
   "text": "smoking",
   "score": 9.867992401123047,
   "articlesIDs": [
    "27820947",
    "19224548"
   ]
  },
  {
   "text": "aluminium (al)",
   "score": 9.860433578491211,
   "articlesIDs": [
    "18084647"
   ]
  },
  {
   "text": "rapid bone growth during puberty and in utero",
   "score": 9.85684585571289,
   "articlesIDs": [
    "21465145"
   ]
  },
  {
   "text": "individuals with dba",
   "score": 9.854774475097656,
   "articlesIDs": [
    "11196268"
   ]
  },
  {
   "text": "g-t-t-g and a-t-t-g haplotypes (rs235764-rs3178250-rs235768-rs1005464)",
   "score": 9.85224723815918,
   "articlesIDs": [
    "25391427"
   ]
  },
  {
   "text": "dba. a young age at presentation",
   "score": 9.847152709960938,
   "articlesIDs": [
    "11196268"
   ]
  },
  {
   "text": "simian virus (sv)40",
   "score": 9.845935821533203,
   "articlesIDs": [
    "15889993"
   ]
  },
  {
   "text": "rs11866002 in cnot1",
   "score": 9.838759422302246,
   "articlesIDs": [
    "25663449"
   ]
  },
  {
   "text": "early-onset (\u003c 25 years) osteosarcoma in offspring",
   "score": 9.827472686767578,
   "articlesIDs": [
    "16859907"
   ]
  },
  {
   "text": "igf-1 polymorphisms",
   "score": 9.82168960571289,
   "articlesIDs": [
    "29232358"
   ]
  },
  {
   "text": "patients aged 65-74 years who had comorbidities such as kidney dysfunction",
   "score": 9.81971549987793,
   "articlesIDs": [
    "32764814"
   ]
  },
  {
   "text": "early-onset chondrosarcoma by parental kidney cancers (sir 6.8). bone cancers",
   "score": 9.789215087890625,
   "articlesIDs": [
    "11809347"
   ]
  },
  {
   "text": "truncating c-terminal variant (c.2663+2t\u003ec)",
   "score": 9.788506507873535,
   "articlesIDs": [
    "29662154"
   ]
  },
  {
   "text": "patients with chemotherapy-sensitive",
   "score": 9.778579711914062,
   "articlesIDs": [
    "24752471"
   ]
  },
  {
   "text": "hematological malignancy, 3.1% (95% ci 2.2-4.3); retinoblastoma",
   "score": 9.751754760742188,
   "articlesIDs": [
    "29869758"
   ]
  },
  {
   "text": "gestational hypertension and reduced risk associated with cesarean section",
   "score": 9.751653671264648,
   "articlesIDs": [
    "24313390"
   ]
  },
  {
   "text": "with bone tissue exposed to 1-4 gy",
   "score": 9.7432279586792,
   "articlesIDs": [
    "37235821"
   ]
  },
  {
   "text": "breast cancer (bc)",
   "score": 9.728386878967285,
   "articlesIDs": [
    "29019328"
   ]
  },
  {
   "text": "bpa exposure interacts with the -22 g/c",
   "score": 9.718873977661133,
   "articlesIDs": [
    "23886186"
   ]
  },
  {
   "text": "art use was highest among children with osteosarcoma",
   "score": 9.715563774108887,
   "articlesIDs": [
    "35929579"
   ]
  },
  {
   "text": "lytic tumors",
   "score": 9.708083152770996,
   "articlesIDs": [
    "26421404"
   ]
  },
  {
   "text": "questionnaire (or = 3.19, 95% ci: 1.54, 6.59), postage stamps",
   "score": 9.692519187927246,
   "articlesIDs": [
    "30689685"
   ]
  },
  {
   "text": "the prevalence of the -22c allele and 473a allele",
   "score": 9.677406311035156,
   "articlesIDs": [
    "22911823"
   ]
  },
  {
   "text": "pediatric solid tumor, 2.5% (95% ci 1.3-4.2); brain tumors",
   "score": 9.66253662109375,
   "articlesIDs": [
    "29869758"
   ]
  },
  {
   "text": "male lb. male lb that developed primary bone cancer later in life",
   "score": 9.657270431518555,
   "articlesIDs": [
    "25732913"
   ]
  },
  {
   "text": "radiation therapy and type of surgery",
   "score": 9.656375885009766,
   "articlesIDs": [
    "31519610"
   ]
  },
  {
   "text": ", individuals with high birth-weight (≥ 4,046 g)",
   "score": 9.62625789642334,
   "articlesIDs": [
    "21465145"
   ]
  },
  {
   "text": "older age, lower educational attainment, underweight or obese status, smoking",
   "score": 9.617337226867676,
   "articlesIDs": [
    "19224548"
   ]
  },
  {
   "text": "birthweight, a known hepatoblastoma risk factor. art use",
   "score": 9.607402801513672,
   "articlesIDs": [
    "35929579"
   ]
  },
  {
   "text": "t allele and tt genotype of c.44c\u003et and c allele and cc genotype of c.1002t\u003ec",
   "score": 9.604728698730469,
   "articlesIDs": [
    "23933591"
   ]
  },
  {
   "text": "age≥60 years, male sex",
   "score": 9.585165023803711,
   "articlesIDs": [
    "26002013"
   ]
  },
  {
   "text": "younger age at diagnosis",
   "score": 9.57313346862793,
   "articlesIDs": [
    "17570705"
   ]
  },
  {
   "text": "south asian ethnic origin",
   "score": 9.55960464477539,
   "articlesIDs": [
    "10755411"
   ]
  },
  {
   "text": "including a questionnaire",
   "score": 9.532842636108398,
   "articlesIDs": [
    "30689685"
   ]
  },
  {
   "text": "1 cm larger cdru",
   "score": 9.515658378601074,
   "articlesIDs": [
    "25732913"
   ]
  },
  {
   "text": "hiv-positive individuals",
   "score": 9.511314392089844,
   "articlesIDs": [
    "23036164"
   ]
  },
  {
   "text": "regions of reduced heterozygosity",
   "score": 9.51111888885498,
   "articlesIDs": [
    "24330828"
   ]
  },
  {
   "text": "per 5-year increase, doxorubicin dose per 10-mg/m increase",
   "score": 9.506117820739746,
   "articlesIDs": [
    "36875898"
   ]
  },
  {
   "text": "long-term exposure to high gh and igf-i",
   "score": 9.498758316040039,
   "articlesIDs": [
    "17259799"
   ]
  },
  {
   "text": "snp rs1050045",
   "score": 9.476896286010742,
   "articlesIDs": [
    "22936702"
   ]
  },
  {
   "text": "those with trunk tumors",
   "score": 9.459501266479492,
   "articlesIDs": [
    "31006987"
   ]
  },
  {
   "text": "snps in risc complex genes",
   "score": 9.44866943359375,
   "articlesIDs": [
    "25663449"
   ]
  },
  {
   "text": "individuals who were less than 25 y of age",
   "score": 9.444441795349121,
   "articlesIDs": [
    "7618957"
   ]
  },
  {
   "text": "the functional mdm2 t309g genetic variant",
   "score": 9.440053939819336,
   "articlesIDs": [
    "22205265"
   ]
  },
  {
   "text": "restriction-fragment-length polymorphisms (rflps)",
   "score": 9.434707641601562,
   "articlesIDs": [
    "2892131"
   ]
  },
  {
   "text": ", 14q32 mirna cluster",
   "score": 9.432649612426758,
   "articlesIDs": [
    "30337581"
   ]
  },
  {
   "text": "mutant genotype of gstp1 rs1695",
   "score": 9.431909561157227,
   "articlesIDs": [
    "36397425"
   ]
  },
  {
   "text": "the mdm2 c.346g\u003ea genetic variant",
   "score": 9.428826332092285,
   "articlesIDs": [
    "25551700"
   ]
  },
  {
   "text": "height and body size",
   "score": 9.428520202636719,
   "articlesIDs": [
    "31130627"
   ]
  },
  {
   "text": ", radiotherapy without chemotherapy",
   "score": 9.42618179321289,
   "articlesIDs": [
    "16152578"
   ]
  },
  {
   "text": "the variant genotypes of rs4938723 tc/cc",
   "score": 9.42563247680664,
   "articlesIDs": [
    "24063968"
   ]
  },
  {
   "text": "metastatic disease at presentation, age≥60 years, male sex",
   "score": 9.416525840759277,
   "articlesIDs": [
    "26002013"
   ]
  },
  {
   "text": "children with a history of hernias",
   "score": 9.404451370239258,
   "articlesIDs": [
    "23036164"
   ]
  },
  {
   "text": "teriparatide use",
   "score": 9.391393661499023,
   "articlesIDs": [
    "32990990"
   ]
  },
  {
   "text": "the ga and aa genotypes of rs3217992 in cdkn2a",
   "score": 9.389754295349121,
   "articlesIDs": [
    "30774116"
   ]
  },
  {
   "text": "age≥60 years, male sex, axial location, and size≥10cm",
   "score": 9.38279914855957,
   "articlesIDs": [
    "26002013"
   ]
  },
  {
   "text": "the g-t-t-g and a-t-t-g haplotypes (rs235764-rs3178250-rs235768-rs1005464)",
   "score": 9.377008438110352,
   "articlesIDs": [
    "25391427"
   ]
  },
  {
   "text": "rottweilers and great danes",
   "score": 9.374191284179688,
   "articlesIDs": [
    "17916033"
   ]
  },
  {
   "text": "grade iii (p = 0.006), localization in the lower limbs",
   "score": 9.373148918151855,
   "articlesIDs": [
    "30989587"
   ]
  },
  {
   "text": "those with osteosarcoma",
   "score": 9.371084213256836,
   "articlesIDs": [
    "29869758"
   ]
  },
  {
   "text": "g allele",
   "score": 9.331157684326172,
   "articlesIDs": [
    "25252845"
   ]
  },
  {
   "text": "cg and gg genotypes of rs12190287",
   "score": 9.329732894897461,
   "articlesIDs": [
    "28663539"
   ]
  },
  {
   "text": "single nucleotide polymorphism (snp) of hsa-mir-124a",
   "score": 9.324772834777832,
   "articlesIDs": [
    "27540978"
   ]
  },
  {
   "text": "bpa exposure interacts with the -22 g/c polymorphism of the lox gene",
   "score": 9.321468353271484,
   "articlesIDs": [
    "23886186"
   ]
  },
  {
   "text": "having bacterial cystitis and appearing again in the vmdb with ubtcc",
   "score": 9.312999725341797,
   "articlesIDs": [
    "26595882"
   ]
  },
  {
   "text": "being a woman",
   "score": 9.307347297668457,
   "articlesIDs": [
    "19224548"
   ]
  },
  {
   "text": "older age (≥65 years)",
   "score": 9.29873275756836,
   "articlesIDs": [
    "30121085"
   ]
  },
  {
   "text": "smoking, and depression",
   "score": 9.29786205291748,
   "articlesIDs": [
    "19224548"
   ]
  },
  {
   "text": "greater distance between the greater trochanter and the nutrient foramen",
   "score": 9.269414901733398,
   "articlesIDs": [
    "10871224"
   ]
  },
  {
   "text": "long-term survivors of childhood and adolescent cancer",
   "score": 9.257299423217773,
   "articlesIDs": [
    "28954302"
   ]
  },
  {
   "text": "cg and gg genotypes as well as the g allele",
   "score": 9.245074272155762,
   "articlesIDs": [
    "25252845"
   ]
  },
  {
   "text": "breed period prevalence of osa was highest for greyhounds",
   "score": 9.236555099487305,
   "articlesIDs": [
    "17916033"
   ]
  },
  {
   "text": "among gardeners",
   "score": 9.23559856414795,
   "articlesIDs": [
    "23036164"
   ]
  },
  {
   "text": "fos dysfunction",
   "score": 9.222282409667969,
   "articlesIDs": [
    "22723319"
   ]
  },
  {
   "text": "with paternally inherited hypomorphic pathogenic variants",
   "score": 9.220536231994629,
   "articlesIDs": [
    "29662154"
   ]
  },
  {
   "text": "osteosarcoma, chondrosarcoma",
   "score": 9.201932907104492,
   "articlesIDs": [
    "3480957"
   ]
  },
  {
   "text": "possess aa genotype of -308 g/a locus",
   "score": 9.181715965270996,
   "articlesIDs": [
    "26097610"
   ]
  },
  {
   "text": "children with osteosarcoma and chondrosarcoma",
   "score": 9.17599868774414,
   "articlesIDs": [
    "3480957"
   ]
  },
  {
   "text": "exonic substitution with a \"leaky\" splicing effect (c.1331a\u003eg)",
   "score": 9.157527923583984,
   "articlesIDs": [
    "29662154"
   ]
  },
  {
   "text": "offspring of hypertensive mothers",
   "score": 9.15005874633789,
   "articlesIDs": [
    "24313390"
   ]
  },
  {
   "text": "intramedullary infarction occurs after canine tha",
   "score": 9.135849952697754,
   "articlesIDs": [
    "10871224"
   ]
  },
  {
   "text": "her-2/neu gene amplification",
   "score": 9.129877090454102,
   "articlesIDs": [
    "12544770"
   ]
  },
  {
   "text": "loss of the rb-1 suppressor gene on chromosome 13q",
   "score": 9.119397163391113,
   "articlesIDs": [
    "2488230"
   ]
  },
  {
   "text": "mothers presented with breast cancer",
   "score": 9.113168716430664,
   "articlesIDs": [
    "16859907"
   ]
  },
  {
   "text": "osteosarcoma, and chondrosarcoma",
   "score": 9.11171817779541,
   "articlesIDs": [
    "3352541"
   ]
  },
  {
   "text": "retinoblastoma, 6.6% (95% ci 1.5-16.8); pediatric solid tumor",
   "score": 9.099634170532227,
   "articlesIDs": [
    "29869758"
   ]
  },
  {
   "text": "ewing sarcoma family of tumours (esft)",
   "score": 9.098307609558105,
   "articlesIDs": [
    "18353632"
   ]
  },
  {
   "text": "treatments with cranial radiation or amputation",
   "score": 9.095149993896484,
   "articlesIDs": [
    "19224548"
   ]
  },
  {
   "text": "the allele-a and genotype-aa of mdm2 c.346g\u003ea genetic variant",
   "score": 9.083144187927246,
   "articlesIDs": [
    "25551700"
   ]
  },
  {
   "text": "type of the first tumor",
   "score": 9.066259384155273,
   "articlesIDs": [
    "12637473"
   ]
  },
  {
   "text": "being a woman, black race",
   "score": 9.043663024902344,
   "articlesIDs": [
    "19224548"
   ]
  },
  {
   "text": "being a woman, black race, older age",
   "score": 9.027475357055664,
   "articlesIDs": [
    "19224548"
   ]
  },
  {
   "text": "to 5-9 gy",
   "score": 9.014135360717773,
   "articlesIDs": [
    "37235821"
   ]
  },
  {
   "text": "the type of the first tumor",
   "score": 9.000792503356934,
   "articlesIDs": [
    "12637473"
   ]
  },
  {
   "text": "wilms tumor (sir, 3.1; 95% ci, 1.7-5.7), leukemia",
   "score": 8.975653648376465,
   "articlesIDs": [
    "36444554"
   ]
  },
  {
   "text": "female osteosarcoma",
   "score": 8.946996688842773,
   "articlesIDs": [
    "9762947"
   ]
  },
  {
   "text": "chondrosarcoma, retinoblastoma",
   "score": 8.934657096862793,
   "articlesIDs": [
    "3480957"
   ]
  },
  {
   "text": "tibial plateau levelling osteotomy (tplo)",
   "score": 8.932393074035645,
   "articlesIDs": [
    "25079048"
   ]
  },
  {
   "text": "gstp1 polymorphism (b",
   "score": 8.931077003479004,
   "articlesIDs": [
    "30909663"
   ]
  },
  {
   "text": "adrenal cortical carcinoma",
   "score": 8.923444747924805,
   "articlesIDs": [
    "3480957"
   ]
  },
  {
   "text": "survivors of hodgkin lymphoma (hl)",
   "score": 8.918410301208496,
   "articlesIDs": [
    "36444554"
   ]
  },
  {
   "text": "contamination of poliovirus vaccines with sv40",
   "score": 8.905540466308594,
   "articlesIDs": [
    "15889993"
   ]
  },
  {
   "text": "cytotoxic t-lymphocyte antigen-4 gene (ctla-4)",
   "score": 8.900670051574707,
   "articlesIDs": [
    "24078408"
   ]
  },
  {
   "text": "il-1b gene polymorphisms",
   "score": 8.897722244262695,
   "articlesIDs": [
    "24878968"
   ]
  },
  {
   "text": "in individuals with paget disease of bone, after therapeutic radiation",
   "score": 8.884867668151855,
   "articlesIDs": [
    "21437228"
   ]
  },
  {
   "text": "the aa, ag, and gg types of gstp1 c.313a\u003eg variant",
   "score": 8.875030517578125,
   "articlesIDs": [
    "36397425"
   ]
  },
  {
   "text": "initial tumor volume, tumor enlargement",
   "score": 8.864262580871582,
   "articlesIDs": [
    "22009712"
   ]
  },
  {
   "text": "-31 c allele",
   "score": 8.859624862670898,
   "articlesIDs": [
    "24878968"
   ]
  },
  {
   "text": "loh18cr)",
   "score": 8.857061386108398,
   "articlesIDs": [
    "12673693"
   ]
  },
  {
   "text": "family history and young age of onset",
   "score": 8.853507995605469,
   "articlesIDs": [
    "29019328"
   ]
  },
  {
   "text": "the mdm2 polymorphism t309g",
   "score": 8.849543571472168,
   "articlesIDs": [
    "19451596"
   ]
  },
  {
   "text": "four polymorphisms in pre-mirnas at 14q32 mirna cluster",
   "score": 8.831377029418945,
   "articlesIDs": [
    "30337581"
   ]
  },
  {
   "text": "the genotypes/alleles of c.75g[c and c.326g[a genetic polymorphisms",
   "score": 8.813623428344727,
   "articlesIDs": [
    "24078408"
   ]
  },
  {
   "text": "comorbidities such as kidney dysfunction and high levels of hba1c",
   "score": 8.79954719543457,
   "articlesIDs": [
    "32764814"
   ]
  },
  {
   "text": "brain tumors, 5.2% (95% ci 1.7-11.8) bone/soft tissue sarcoma",
   "score": 8.79660415649414,
   "articlesIDs": [
    "29869758"
   ]
  },
  {
   "text": "loss of function of both copies of a tumor suppressor gene (rb1)",
   "score": 8.789243698120117,
   "articlesIDs": [
    "8391274"
   ]
  },
  {
   "text": "including a questionnaire (or = 3.19, 95% ci: 1.54, 6.59), postage stamps",
   "score": 8.777124404907227,
   "articlesIDs": [
    "30689685"
   ]
  },
  {
   "text": "osteosarcoma-associated loci and regions of reduced heterozygosity",
   "score": 8.75799560546875,
   "articlesIDs": [
    "24330828"
   ]
  },
  {
   "text": "patients in the osteosarcopenia group",
   "score": 8.747767448425293,
   "articlesIDs": [
    "32764814"
   ]
  },
  {
   "text": "osteosarcoma, chondrosarcoma, retinoblastoma",
   "score": 8.74325942993164,
   "articlesIDs": [
    "3480957"
   ]
  },
  {
   "text": "patients with regional node involvement",
   "score": 8.733992576599121,
   "articlesIDs": [
    "23867123"
   ]
  },
  {
   "text": "pgp positivity, as determined by immunohistochemistry",
   "score": 8.713598251342773,
   "articlesIDs": [
    "12879476"
   ]
  },
  {
   "text": "her-2/neu expression in patients with osteosarcoma",
   "score": 8.691848754882812,
   "articlesIDs": [
    "12544770"
   ]
  },
  {
   "text": "patients receiving neither cyclophosphamide nor etoposide",
   "score": 8.69064712524414,
   "articlesIDs": [
    "8202048"
   ]
  },
  {
   "text": "bone:stem ratio",
   "score": 8.679828643798828,
   "articlesIDs": [
    "21968899"
   ]
  },
  {
   "text": "being either underweight or obese",
   "score": 8.679518699645996,
   "articlesIDs": [
    "27820947"
   ]
  },
  {
   "text": "patients who were treated for os",
   "score": 8.679422378540039,
   "articlesIDs": [
    "18823030"
   ]
  },
  {
   "text": "postage stamps (or = 1.60, 95% ci: 1.21, 2.12), and incentives",
   "score": 8.661004066467285,
   "articlesIDs": [
    "30689685"
   ]
  },
  {
   "text": "those receiving cyclophosphamide but no etoposide",
   "score": 8.651594161987305,
   "articlesIDs": [
    "8202048"
   ]
  },
  {
   "text": "adrenal cortical carcinoma, osteosarcoma, chondrosarcoma",
   "score": 8.633522987365723,
   "articlesIDs": [
    "3480957"
   ]
  },
  {
   "text": "cs (vs. ps + ns)",
   "score": 8.631547927856445,
   "articlesIDs": [
    "21978922"
   ]
  },
  {
   "text": "and residence in a population of less than 9,000",
   "score": 8.623634338378906,
   "articlesIDs": [
    "7618957"
   ]
  },
  {
   "text": "chondrosarcoma, retinoblastoma)",
   "score": 8.597299575805664,
   "articlesIDs": [
    "3480957"
   ]
  },
  {
   "text": "an earlier adolescent growth period, and earlier attainment of final height",
   "score": 8.573487281799316,
   "articlesIDs": [
    "17106438"
   ]
  },
  {
   "text": "the older age, black and earlier period of diagnosis",
   "score": 8.568205833435059,
   "articlesIDs": [
    "35116667"
   ]
  },
  {
   "text": "those of south asian ethnic origin",
   "score": 8.566287994384766,
   "articlesIDs": [
    "10755411"
   ]
  },
  {
   "text": "and fluoride in drinking water",
   "score": 8.540328979492188,
   "articlesIDs": [
    "24425828"
   ]
  },
  {
   "text": "radiotherapy cancer treatment",
   "score": 8.530319213867188,
   "articlesIDs": [
    "37182536"
   ]
  },
  {
   "text": "treatment for malignant bone tumors",
   "score": 8.53009033203125,
   "articlesIDs": [
    "18823030"
   ]
  },
  {
   "text": "the genotype cc of il-6 -174 g/c",
   "score": 8.482418060302734,
   "articlesIDs": [
    "26810186"
   ]
  },
  {
   "text": "children with soft tissue sarcoma, osteosarcoma, and chondrosarcoma",
   "score": 8.452841758728027,
   "articlesIDs": [
    "3352541"
   ]
  },
  {
   "text": "locoregional surgery or radiotherapy cancer treatment",
   "score": 8.443472862243652,
   "articlesIDs": [
    "37182536"
   ]
  },
  {
   "text": "survivors of ewing's sarcoma",
   "score": 8.440587997436523,
   "articlesIDs": [
    "1729013"
   ]
  },
  {
   "text": "individuals aged 15 years or less",
   "score": 8.436225891113281,
   "articlesIDs": [
    "22471480"
   ]
  },
  {
   "text": "-31 cc genotype",
   "score": 8.432419776916504,
   "articlesIDs": [
    "24878968"
   ]
  },
  {
   "text": "childhood cancer survivors (ccss)",
   "score": 8.4290771484375,
   "articlesIDs": [
    "30053029"
   ]
  },
  {
   "text": "the tgfbr1*6a variants",
   "score": 8.415563583374023,
   "articlesIDs": [
    "20429896"
   ]
  },
  {
   "text": "heterozygotic and homozygotic tgfbr1*6a variants",
   "score": 8.41346549987793,
   "articlesIDs": [
    "20429896"
   ]
  },
  {
   "text": "the genotypes/alleles of c.44c\u003et and c.1002t\u003ec",
   "score": 8.401535034179688,
   "articlesIDs": [
    "23933591"
   ]
  },
  {
   "text": "pubertal spurt",
   "score": 8.398802757263184,
   "articlesIDs": [
    "15956884"
   ]
  }
 ]
}