risks-factors / H00039.json
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risk factors
c8f8834 unverified
{
"id": "H00039",
"disease": {
"id": "H00039",
"names": [
"Basal cell carcinoma"
],
"dbLinks": {
"icd10": [
"C44"
],
"mesh": [
"D002280"
]
},
"category": "Cancer"
},
"riskFactors": [
{
"text": "cumulative use of high-ceiling diuretics",
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{
"text": "patients with a diagnosis of actinic keratosis",
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{
"text": "blond or red hair colors",
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{
"text": "young age at transplantation",
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{
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{
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{
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{
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"text": "skin cancer before transplantation, previous transplantation",
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"text": "mountaineering in childhood",
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"text": "patients on immunosuppressive medication for at least one year",
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"text": "male sex, uv radiation-sensitive phenotypes",
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"text": "number of moles",
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"text": "intakes of total furocoumarins as well as some individual furocoumarins",
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"text": "life-long radiation exposure, male sex, fair skin, history of prior nmsc",
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{
"text": "infiltrating/mixed-infiltrating subtypes",
"score": 11.494707107543945,
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{
"text": "women reporting natural menopause who used mht for 10 or more years",
"score": 11.488555908203125,
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{
"text": "blacks of having sickle cell anemia",
"score": 11.488515853881836,
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{
"text": "patients living in rural counties",
"score": 11.488153457641602,
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{
"text": "increasing number of variant il10 haplotypes",
"score": 11.48298454284668,
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{
"text": "sectors with higher radon levels",
"score": 11.480024337768555,
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{
"text": "male gender, more advanced age at transplantation",
"score": 11.473782539367676,
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{
"text": "polygenic risk scores (prs)",
"score": 11.472095489501953,
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{
"text": "and cutis rhomboidalis nuchae",
"score": 11.468696594238281,
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{
"text": "organ-transplant recipients in the top 20% prs",
"score": 11.463530540466309,
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{
"text": "high photoaging score [≥30], and the presence of actinic keratosis)",
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{
"text": "ra patients and rates of nmsc were higher in patients with psoriasis",
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{
"text": "lung transplant recipients",
"score": 11.457792282104492,
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{
"text": "presence of actinic keratoses (aks)",
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{
"text": "mountainous area of birth, past history of bcc",
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{
"text": "hpv-induced verrucae vulgares",
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{
"text": "initial or frequent tumor location on the trunk or on the upper limbs",
"score": 11.441926956176758,
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{
"text": "chronic lymphocytic leukaemia (cll) and non-melanoma skin cancer (nmsc)",
"score": 11.440811157226562,
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{
"text": "preoperative tumor size and postoperative defect size of ≥3 cm",
"score": 11.439238548278809,
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{
"text": "patients who are relatively young at their first bcc diagnosis",
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{
"text": "exposure to ias through drinking water with concentrations \u003c 100 μg/l",
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{
"text": "red hair (adjusted or, 1.43; 95% ci, 1.05-1.94), high educational level",
"score": 11.434734344482422,
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{
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{
"text": "a high dose of immunosuppression related to a specific type of graft",
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{
"text": "family history of bcc, immune suppression",
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{
"text": "recessive dystrophic epidermolysis bullosa (rdeb)",
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{
"text": "higher nevus prs quartiles",
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{
"text": "excessive sun-exposure during adulthood",
"score": 11.413896560668945,
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{
"text": "chronic venous insufficiency (cvi)",
"score": 11.409322738647461,
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{
"text": "tt genotype in the foki vdr polymorphism",
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{
"text": "diuretic use in overweight and obese participants",
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{
"text": "increase in number of sunburns at any age",
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{
"text": "higher ambient uv exposure in the past 10 years",
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{
"text": "previous history of non-melanoma skin cancer",
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{
"text": "il-2 -330 gg genotype or il-10 -1082 ga",
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{
"text": "those aged 65-79years",
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{
"text": "high counts of actinic keratoses (field cancerisation)",
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{
"text": "immune suppression and fair complexion, especially red hair",
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{
"text": "ct genotype in 677c/t mthfr polymorphism",
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{
"text": "a first post-transplant nmsc",
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{
"text": "hiv(+) subjects",
"score": 11.348150253295898,
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{
"text": "patients with only cscc",
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{
"text": "total fat intake increased in people with a history of skin cancer",
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{
"text": "progressive accumulation of sun exposure",
"score": 11.34278678894043,
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{
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{
"text": "synchronous basosquamous cell carcinoma",
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{
"text": "for every 10-gram increase in ethanol intake per day",
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{
"text": "patients with nmsc",
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{
"text": "patients with darker skin types",
"score": 11.335926055908203,
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{
"text": "with ever experiencing a sunburn in childhood",
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{
"text": "patients with recessive dystrophic epidermolysis bullosa (rdeb)",
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{
"text": "hpv, including multiple hpv types",
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{
"text": "cutaneous scc occurrence after transplantation",
"score": 11.331867218017578,
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{
"text": "older age, nodular bcc, or face involvement at the first diagnosis",
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{
"text": "long-term cumulative sun exposure assessed by self-reported outdoor work",
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{
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{
"text": "il-10 -1082 aa or ga and il-2 -330 gg genotype",
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{
"text": "heart transplant recipients",
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{
"text": "older age at transplantation and at the first consultation",
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{
"text": "peak daily ias dose rate, cumulative ias dose",
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{
"text": "older age (median 79 versus 62 y, p \u003c 0.001), male sex",
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{
"text": "occupational exposure to ionising radiation from cosmic sources",
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{
"text": "lymphoproliferative disorders (ld)",
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"text": "having a skin cancer before transplantation",
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{
"text": "peripheral leukocytes telomere length (pltl)",
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{
"text": "recipients who started with bcc",
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{
"text": "many (11 or more) forearm naevi compared with no forearm naevi",
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{
"text": "rt patients",
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{
"text": "participants with ≥5 blistering sunburns",
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{
"text": "pregnant women",
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{
"text": "tyr ser192tyr",
"score": 11.240060806274414,
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"text": "participants with hazel/green/medium and blue/light colors",
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{
"text": "hctz compared with acei",
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{
"text": "inorganic arsenic (ias)",
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{
"text": "age (odds ratio [or], 1.05; 95% ci, 1.03-1.07; p \u003c .001), number of sunburns",
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"text": "those treated with the antifungal medication voriconazole",
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"text": "one cup of coffee, 0.92 (95% ci: 0.88-0.97) for one to two cups of coffee",
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{
"text": "6 or more moles on the left arm",
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"text": "those first diagnosed with bcc-only, scc-only or synchronous bcc and scc",
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"text": "participants with the bsmi snp",
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{
"text": "men, those without a regular dermatologist",
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"text": "years using regular indoor tanning devices",
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"text": "prostate, and lung and trachea cancer survivors",
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{
"text": "women with melanoma were more likely to have a family history of melanoma",
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"text": "a personal history of nonmelanoma skin cancer (nmsc)",
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"text": "patients older than 50 years at transplantation",
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"text": "exposure to sunlight, especially uvb spectrum",
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"text": "melanoma survivors",
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"text": "mountaineering increase the risk of bcc. surfing and swimming",
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"text": "pregnant women, people with skin cancer or a history of skin cancer",
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"text": "bazex-dupré-christol syndrome, rombo syndrome, and oley syndrome",
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"text": "radiation therapy, family history of bcc, immune suppression",
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"text": "users of hctz also",
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"text": "human papillomavirus (hpv)",
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"text": "history of radiation exposure",
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"text": "patients who were treated with cyclosporine as immunosuppressant",
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"text": "beta-pv-seropositive otr around the time of transplantation",
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"text": "patients with bcc worked outdoor jobs for longer lengths of time",
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"text": "increased ultraviolet radiation exposure (uvr)",
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"text": "subjects who received 35 gy or more to the skin site vs no radiation therapy",
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"text": "black, blue, and red inks",
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"text": "a first post-transplant nmsc, particularly a scc",
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{
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{
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{
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{
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{
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{
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