secondary_dose_response_curve_parameters

## Dose-response files:
secondary_dose_response_curve_parameters - Table
Parameters of dose-response curves fit to replicate-level viability data using a four-parameter log-logistic function with the drc R package.
broad_id - ID used to identify drug-batch combinations
name - name of drug

depmap_id - ID to identify a cell line
ccle_name - ID to identify a cell line
screen_id - ID to identify a screen
upper_limit - limit of curve as dose approaches infinite
lower_limit - limit of curve as dose approaches zero
slope -
convergence - indicates if the dose-response curve fitting procedure converged
r2 - goodness of fit measure between dose response curve and replicate viability data
auc - area under the dose response curve
ec50 - dose of inflection point of dose response curve
ic50 - dose that corresponds to a viability of 50 on the dose response curve
moa - Broad Repurposing Hub mechanism of action annotation
target- Broad Repurposing Hub gene target annotation
disease.area - Broad Repurposing Hub disease area annotation
indication - Broad Repurposing Hub indication annotation
smiles - simplified molecular-input line-entry system molecular identifier
phase - Broad Repurposing Hub latest-clinical phase annotation
passed_str_profiling - indicator for problems identified by STR profiling

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