---
license: cc-by-4.0
---

# Dataset Card for UniProt Gene Lookup

## Dataset Details

### Dataset Description

This dataset is a lookup table of gene information curated from the reviewed entries of UniProtKB/Swiss-Prot. The dataset contains the protein-coding gene data, curated by expert biocurators to ensure high-quality and experimentally validated information. It is designed to assist researchers in mapping genes to corresponding protein sequences, functional annotations, and associated metadata.

- **Curated by:** The UniProt Consortium (European Bioinformatics Institute (EBI), Georgetown University, University of Delaware, Swiss Institute of Bioinformatics (SIB)).
- **Language(s) (NLP):** Not applicable (This dataset focuses on biological data).
- **License:** Creative Commons Attribution 4.0 International (CC BY 4.0)【7†source】.

### Dataset Sources

- **Repository:** [UniProtKB](https://www.uniprot.org/uniprotkb?query=reviewed:true) (Query: reviewed:true).
- **Paper:** "UniProt: the Universal Protein Knowledgebase in 2023," Nucleic Acids Research, Vol. 51, D523–D531【7†source】.
- **Demo:** Not available.

## Uses

### Direct Use

This dataset is suitable for biological research, particularly in bioinformatics, genomics, and proteomics. It can be used for gene annotation, protein function prediction, and understanding gene-protein relationships.

### Out-of-Scope Use

This dataset may not be suitable for natural language processing tasks or non-biological fields. Misuse could include applications that do not consider the scientific validity or limitations of the curated gene annotations.

## Dataset Structure

The dataset is structured as a tab-separated values (TSV) file containing gene identifiers, protein sequences, functional annotations, and associated metadata.

## Dataset Creation

### Curation Rationale

This dataset was created to provide researchers with a high-quality resource for gene-to-protein mapping, emphasizing experimentally verified annotations. It helps streamline bioinformatics workflows by providing reliable data that reduces the need for extensive literature searches.

### Source Data

#### Data Collection and Processing

The data was collected from UniProtKB/Swiss-Prot, the reviewed section of UniProt. The dataset is curated by expert biocurators who continuously update it based on new scientific literature and computational predictions.

#### Who are the source data producers?

The source data producers include the UniProt Consortium, which integrates biological knowledge from multiple external resources and community contributions.

## Bias, Risks, and Limitations

This dataset may have limitations in terms of coverage for less-studied organisms or gene variants that have not been experimentally validated. Researchers should consider potential biases in gene annotations, especially for organisms with fewer studies.

### Recommendations

Researchers are advised to cross-check the dataset with the latest scientific literature and use it as a supplementary tool rather than a definitive source for gene annotations.

## Citation

Please cite the dataset using the following BibTeX:

```bibtex
@article{UniProt2023,
  author = {The UniProt Consortium},
  title = {UniProt: the Universal Protein Knowledgebase in 2023},
  journal = {Nucleic Acids Research},
  year = {2023},
  volume = {51},
  number = {D1},
  pages = {D523--D531},
  doi = {10.1093/nar/gkac1052},
  url = {https://www.uniprot.org/uniprotkb?query=reviewed:true}
}
```

## Dataset Card Authors

- Don Branson

## Dataset Card Contact

- [dwb2023](https://huggingface.co/dwb2023)