sentence: This class of secretory cargoes such as Acb1 , superoxide dismutase-1 ( SOD1 ) , interleukin-1 β ( IL-1 β ) , and insulin-degrading enzymes is mostly released in a cell type – dependent manner in association with specific environmental conditions and cellular stress ( Kinseth et al ., 2007 ; Nickel and Rabouille , 2009 ; Nickel , 2010 ; Rabouille et al ., 2012 ; Malhotra , 2013 ; Zhang and Schekman , 2013 ) .