sentence: To investigate this , we examined the consequences of G9a / GLP-dependent H3K9me2 patterning on chromatin structure in HSPCs using FAIRE-seq ( Formaldehyde Assisted Isolation of Regulatory Elements Sequencing ) [ 13 ] to map accessible chromatin in CD34 HSPCs treated with UNC0638 or dimethyl sulfoxide ( DMSO ) control ( see Methods and Additional file 1 : Table S1 ) .