sentence: Adenoviridae and Poxviridae contain human pathogens , but d0-d5 virtigs were similar to proteins of animal pathogens in these groups.Virtigs were similar to “ giruses ” , that is , viruses with very large genomes ( > 0.5Mb ) , including Acanthamoeba polyphaga mimivirus ( 1.18Mb ) , Acanthamoeba polyphaga moumouvirus ( 1.02 Mb ) , Cafeteria roenbergensis virus BV-PV1 ( 0.62 Mb ) , Megavirus chiliensis ( 1.26Mb ) , Megavirus lba ( 1.23Mb ) , Pandoravirus dulcis ( 1.92 Mb ) , Pandoravirus salinus ( 2.4 Mb ) and Pithovirus sibericum ( 0.61 Mb ) .