sentence: Treatment with oltipraz inhibited the microglial activation but did not prevent the upregulation of PI3K or p-Akt in this brain area.Our findings also revealed that sciatic nerve injury decreased the expression of Nrf2 ( F ( 2,9 ) = 6.30 , p < 0.019 , one-way ANOVA vs. the sham-operated mice treated with vehicle ; Figure 7A ) and HO-1 ( F ( 2,9 ) = 10.07 , p < 0.005 , one-way ANOVA vs. the sham-operated mice treated with vehicle ; Figure 7B ) .