sentence: For example , Akt1 is mostly cytoplasmic in ovarian nurse cells , but rather membrane localized in eye imaginal discs.27 ,29 Lipid metabolism in the ovary is regulated by Akt1 under the control of Wdb , involving a direct molecular interaction of the 2 proteins not seen under normal conditions in imaginal tissues.27 ,29 This specific interaction appears to require CycG , since in cycG mutants , Akt1 and Wdb can be co-precipitated from extracts of fly heads .