sentence: Classification provided by a further phylogenetic analysis were consistent with a role for these genes in detoxification ; the T. notatus GST belongs to the delta class , which is thought to function together with members of the epsilon class in xenobiotic metabolism [ 60 ] , and the four down-regulated T. notatus P450s belong to the CYP3 clan which has been linked to xenobiotic metabolism and insecticide resistance [ 6 ] .