sentence: mSIRK-induced Ca elevation similarly observed in various melanoma cells including WM1552C , a regional growth pattern primary melanoma cell line ( RGP ) , WM115 , WM1361A , WM3284 , vertical growth pattern primary melanoma cells ( VGP ) , and SK-Mel-24 , SK-Mel-187 and C8161 , metastatic melanoma cell lines ( MM ) ( data not shown ) , suggesting mSIRK 's effect on Ca is universal in different types of melanoma .