sentence: We then found that , 4-methyl-4 ' - [ 3,5 - bis ( trifluoromethyl ) -1 H-pyrazol-1-yl ] -1,2,3 - thiadi azole-5-carboxanilide ( YM58483 ) , which is known as an antagonist for Ca - activated Ca channels ( CRAC ) [ 27 ] or canonical transient receptor potential ( TRP ) channels [ 28 ] , inhibited mSIRK-induced Ca signal ( Figure 4b ) .