sentence: We performed the multiple sequence alignment of M. tuberculosis BioA with its homologs from the other organisms such as Saccharomyces cerevisiae , Haemophilus influenzae , Serratia marcescens , Escherichia coli , Erwinia herbicola , Brevibacterium flavum , Mycobacterium leprae , Bacillus subtilis , Methanococcus jannaschii , Bacillus sphaericus and Helicobacter pylori ( Figure S6 ) .38 It was found that residues Trp65 , Tyr157 , Lys283 and Arg400 were conserved in all species and the residues Tyr25 , Trp64 and Phe402 were found to be present in most of the species .