sentence: The meta-analysis was performed for the remaining six miRNA polymorphisms , including miR-146a rs2910164 ( 30 studies , 13,186 cases and 14,497 controls ) , miR-149 rs2292832 ( nine studies , 4116 cases and 3511 controls ) , miR-149 rs71428439 ( three studies , 1556 cases and 1567 controls ) , miR-196a2 rs11614913 ( 20 studies , 10,144 cases and 10,432 controls ) , miR-218 rs11134527 ( three studies , 2322 cases and 2754 controls ) and miR-499 rs3746444 ( 20 studies , 9564 cases and 8876 controls ) .