sentence: In C57BL / 6J mice with neuropathic pain induced by chronic constriction of the sciatic nerve ( CCI ) , we evaluated the effects of oltipraz , an antioxidant and anticancer compound , on ( 1 ) allodynia and hyperalgesia , ( 2 ) microglial activation and pain signaling pathways , ( 3 ) oxidative stress , and ( 4 ) depressive-like behaviors .