sentence: As the results were observed in other lasso peptides25 , lariatin B and all the variants also seems to be labile to the hydrolysis by unspecific peptidase in the C-terminal region.The biosynthesis and mutational analysis of lasso peptides such as microcin J25 , capistruin , astexin-1 , caulosegnin I and xanthomonin II ( Fig. S8 ) were extensively studied .