sentence: Other significantly down-regulated genes in the DFI < 100 cohort were : alcohol dehydrogenase , iron containing 1 ( ADHFE1 , fold change = 3.56 , p = 0.001 , Figure 2B ) , coiled-coil domain containing 3 ( CCDC3 , fold change = 7.30 , p < 0.001 , Figure 2C ) , sodium channel , voltage-gated , type I , beta ( SCN1B , fold change = 3.72 , p = 0.002 , Figure 2D ) , angiotensin II receptor , type 1 ( AGTR1 , fold change = 7.14 , p = 0.003 , Figure 2E ) , and n-myc downstream-regulated gene family member 2 ( NDRG2 , fold change = 4.29 , p = 0.005 , Figure 2F ) .