sentence: The importance of the transmembrane protein 106B ( TMEM106B ) gene , identified by the first GWAS on FTD patients ( Van Deerlin et al ., 2010 ) , has been confirmed in different studies ( Busch et al ., 2016 ; Nicholson and Rademakers , 2016 ; Gallagher et al ., 2017 ; Rhinn and Abeliovich , 2017 ) .