sentence: The initial association is a lipid-sensitive binding to the membrane , followed by voltage-dependent blockage of the VDAC pore , where the disordered acidic C-terminal peptide of either α - syn or tubulin is required for VDAC blockage ( Rostovtseva et al ., 2008 , 2017 ; Gurnev et al ., 2011 ; Noskov et al ., 2016 ) .