sentence: Therefore , various putative targets for miR-223-3p that are down-regulated in inflamed small-IECs likely participate in either antagonizing ( DUOXA2 or HSP90B1 ) or accelerating ( ACE2 ) inflammatory responses.Inflamed large-IECs contained 9 putative target genes for miR-223-3p whose expression was decreased in the same cells ( Fig. 3 ) : GOLGB1 , TMIGD1 , CHMP4C , SLC4A4 , MLL3 , TMEM140 , ARFRP1 , and TNNI1 .