sentence: Recent comparative genome analysis of different E. cloacae strains showed that E. cloacae ATCC 13047 possesses two different T6SS-like clusters ( Liu et al ., 2013 ) that we named T6SS-1 and T6SS-2 ( Figure 1 ) , suggesting that the presence of two T6SS could provide adaptive advantages for E. cloacae in bacterial competition and virulence , as it has been reported for other bacteria that possess two or more T6SS clusters ( Journet and Cascales , 2016 ; Chen et al ., 2019 ) .