Kai (b. 2001) is a son with Land's former wife Sharon Leal.

Collection: Wikipedia Outlinks March 2016

Crawl of outlinks from wikipedia.org started March, 2016.

These files are currently not publicly accessible.

It has been several years since the last time we did this.

For this collection, several things were done:

This collection will be complete, as there is a

good chance we will share the data, and sharing data with pointers to random

other collections, is a complex problem.

2. For the first time, did all the different wikis.

This one, the seed list was built from all 865 collections.

The Wayback Machine - https://web.archive.org/web/20160304040906/http://bostonpublic.tktv.net/news.html

8.31.06 - Michael Rapaport will be on Jimmy Kimmel Live the night of Friday, September 1st.

8.31.06 - Michael Rapaport will be on The Late Late Show with Craig Ferguson the night of Tuesday, September 12th.

7.28.06 - Rashida Jones will guest star on The Office next season, and may possibly become a recurring character.

Jeri Ryan is engaged to her business partner and boyfriend, French chef Christopher Eme.

Ryan announced her engagement during the Television Critics Association press tour to promote her new TV series, Shark.

5.5.06 - From TVGuide.com: Loretta Devine will costar in the Lifetime Original movie "Life is Not a Fairy Tale: The Fantasia Barrino Story," as Fantasia's grandmother.

Jeri Ryan will guest-star on the May 16 season finale of ABC's Boston Legal, playing a reality-series host charged with shooting dead a member of the paparazzi.

David E. Kelley has a new project at ABC called Life on Mars, based on the BBC sci-fi drama that launched this past January.

The story is about a detective who lives in the 21st century, tho following a car accident inexplicably finds himself living and working in the 1970's.

Kelley will write and exec produce the pilot, which is targeting a Fall 2007 debut.

Jeri Ryan joins James Woods in the new CBS drama project Shark from Spike Lee.

Chi McBride has been cast in the ABC drama project formerly called Nine Lives about a lengthy hostage crisis from the point of vieew of the hostages.

Loretta Devine recently appeared on ABC's Grey's Anatomy as Adele Webber.

She will also be a recurring guest star on the WB's new show, Supernatural, where she plays a psychic who may be able to shed some light on the mystery of the two boys' mother's death.

Michael Rapaport's new sitcom, The War at Home, has been picked up by FOX for a full season.

Rob Estes has replaced Nicky Katt as a lead in ABC's new series, The Evidence.

9.9.05 - From TV Guide Online: Rapaport Armed for The War at Home

Fox's Simpson, Hill, Griffin and Smith families are getting a funny new neighbor: the Golds of The War at Home (premiering Sunday at 8:30 pm/ET).

Playing pop to a trio of challenging teens (blossoming Hillary, sexually misunderstood Larry and videogamer Mike) is Michael Rapaport (Small Time Crooks, Hitch), whose previous TV run was as a firebrand teacher on Boston Public.

TVGuide.com got a few minutes during the busy actor's lunch break to discuss fatherhood, films and his real-life friend in need.

TVGuide.com: What did your three-season stint as Boston Public's Danny teach you?

Michael Rapaport: It taught me that good work is good work, and having the opportunity to act every day is a really special thing.

Did it give you an appetite for further episodic series such as War at Home?

I liked the consistency of the work and, as I said, I enjoy acting a lot.

So often in this business, you rarely get to act; you spend time trying to get jobs and that kind of thing.

But what's great about doing a TV show, especially one that I like, is that you do get to act every day, as opposed to chasing work, which is a real pain in the ass.

Some liken War at Home to Married... with Children.

Rapaport: I think it's more like a Roseanne or an All in the Family.

Although Married... with Children was an extraordinarily funny show, this show is based in a stronger sense of reality.

TVGuide.com: Are you excited about Sunday's premiere?

I'm so proud of this show and so proud of the cast.

I think once people see it they're going to enjoy it.

How do you like Anita Barone (The Jeff Foxworthy Show) as your TV wife?

Dave and Vicky have a good, healthy, fun and playful relationship — they're friends and still very attracted to and sexually into each other.

TVGuide.com: Where are you coming from to play a father of teens?

A big inspiration for me is always my father, and I also sort of take from [creator/executive producer] Rob Lotterstein's inspiration, which is his father.

But the fact that I am a father of two boys — Julian, who's 5, and Maceo, my 3-year-old — is obviously the best firsthand experience I have.

TVGuide.com: What do you make of the pseudo-"controversy" of a show titled The War at Home's debuting on 9/11?

TVGuide.com: Not that you are averse to controversy, which you experienced much of as a cast member of Bamboozled.

It dealt with a lot of stereotypes in the black community and the way they are exploited by Hollywood — the television industry, more specifically — and it didn't pull any punches.

[Writer/director] Spike [Lee] took incredible risks making it, and because of the controversy and all that, it didn't get a chance.

But it's a very, very important movie that people should be able to enjoy for a long time.

TVGuide.com: Are there any new films coming up that you're particularly proud of?

Rapaport: Special, which is going to premiere at the [January 2006] Sundance Film Festival, I'm really excited about.

It's a little independent movie about a guy who is sort of depressed and sheltered and he winds up taking an antidepressant and starts to [experience] adverse reactions — he starts to think he has supernatural powers because the medication doesn't really work properly.

It has a dark, comedic element to it, but it's really a dramatic portrayal of a guy who is suffering from depression and is desperate to try to fix it.

I'm enormously proud of it, and I'm looking forward to people getting a chance to see it.

Lastly, I'd like to ask if you have heard any updates regarding Natasha Lyonne (American Pie).

[Rapaport's longtime friend/Comic Book Villains cast mate was recently in a New York City hospital ICU with hepatitis C, a collapsed lung and a heart infection.]

I've been thinking about her a lot lately and I care about her....

I saw somewhere that her father was threatening the hospital with a lawsuit for violating confidentiality and letting her admittance be leaked out.

The thing about her father that hasn't been put out there is... she doesn't speak to her father — she has a restraining order against him — so he's just trying to get his face into the papers for some reason.

I don't know why a sixtysomething-year-old man would be so interested in getting in the press when his daughter is so sick.

Natasha knows how I feel about her, aside from all the stuff that we went through [when her unruly behavior forced Rapaport to evict Lyonne from an apartment building he owns].

She's a very, very good person, and I'm hoping that she's able to get better.

6.8.05 - Jessalyn Gilsig is being promoted to cast regular on Nip/Tuck.

3.16.05 - Chi McBride has been cast in the Fox drama pilot Deviant Behavior.

Nicky Katt has been added to the cast of The Evidence, a new show from Warner Bros. TV/John Wells Productions starring Martin Landau and Orlando Jones.

It's a procedural drama about two homicide detective, and is being produced for ABC.

Boston Public repeats will premiere on WE on Monday, September 27th, and will be airing at 7pm and 1am on weekdays.

Women's Entertainment has acquired the off-net cable rights to Boston Public.

Boston Public comes with 81 episodes and is scheduled to begin airing on WE this fall.

Jeri Ryan accused her former husband, Republican Senate candidate Jack Ryan, of trying to coerce her into performing sex acts at various clubs while others watched.

The charges -- first leveled during the couple's bitter child-custody battle back in 2000 -- were made public on Monday.

In the documents the actress also acknowledged infidelity on her part, but only after the marriage was irretrievably broken.

David E. Kelley will develop his own reality show that will include real lawyers.

In creating a real firm, the lawyers/players will handle civil cases with binding arbitration presided over by sitting or former judges (the same type of binding arbitration as used in various syndicated court shows), and at the same time be vying for a partnership position within the lawfirm.

NBC has ordered up 8 episodes which will be produced by Kelley and Renegade 83.

Kristin at E!Online reports that when Chi McBride was asked if there was a chance that Boston Public would ever return, McBride just laughed.

"Boston Public is as dead as fried chicken.

There's about as much hope of it returning as a drumstick attaching all the other pieces together and running in your yard."

5.11.04 - Michael Rapaport and wife Nichole are going their separate ways after four years of marriage.

4.7.04 - Zap2It.com: Gilsig Subs for Ross on 'NYPD Blue' -

Charlotte Ross' departure from "NYPD Blue" has opened the door for former "Boston Public" star Jessalyn Gilsig to join the cast....

3.17.04 - From the March 20th issue of TV Guide: Graduation Day

Fox has yet to officially dismiss Boston Public, but there's every indication that school is out for the gang at Winslow High.

"The cast has been released from their contracts, and the show's sets have been torn down," sniffs a Boston native.

Two unaired episodes won't give fans much closure; creator-producer David E. Kelley was not given enough notice to script an appropriate farewell.

Jeri Ryan is in final talks to star opposite Kim Delaney in the pilot for Sudbury, a CBS drama that revolves around two sisters who also happen to be witches.

3.1.04 - Chi McBride will join the cast of Countdown (Fremantle Media/Vertikal/Touchstone) as the SWAT team leader.

McBride's fellow cast members include Jason O'Mara, Louis Mandylor, Salli Richardson, and Adam Beach.

This show was previous known as 43 Minutes.

1.24.04 - Zap2It.com: School Year Ends Early for 'Boston Public' -

While most shows typically complete 22 episodes per season, FOX has halted production on "Boston Public," which was in the middle of shooting its 15th episode this past week.

David E. Kelley's drama, which centers around the lives of students and faculty at a high school, is currently in its fourth season.

Many suspected it would be the show's last since FOX had originally only ordered 13 episodes before tacking on an additional two....

12.15.03 - Zap2It.com: R.E.M. Unplugs for 'Boston Public' -

So many people are crowded into Doyle's Cafe on the set of FOX's "Boston Public" that, if it were a real pub, the place might be in violation of the fire code.

The occasion is the filming of "Chapter Seventy-Six," the Friday, Dec. 19, episode of the high-school drama, and it's far from business as usual on the soundstages in Manhattan Beach, Calif....

10.29.03 - R.E.M. will perform an acoustic version of "Losing My

Religion" during Boston Public's Christmas-themed episode Dec. 19.

of the deal, producers agreed to play the group's new single "Bad Day" in

10.10.03 - From TV Guide Online: "Idol Star Goes Gay for Pay" by Michael Ausiello

American Idol lullababe Tamyra Gray is going from thespian to lesbian.

The Boston Public grad will play a sapphic singer who develops a crush on Rachel True's Mona character on the Nov. 3 episode of UPN's Half & Half.

The 24-year-old crooner admits she had some reservations about making her sitcom debut with such a "challenging" role.

"In the beginning [I was a little apprehensive], but mostly because I didn't know the other actress, Rachel, who I was playing side-by-side with," she tells TV Guide Online.

"But it's kind of lighthearted, so it wasn't so bad.

It wasn't bad at all, actually; it was pretty easy."

In the story, Mona tries to sign a hot new singer named Zora (Gray) to Delicious Records, but the hetero-leaning exec quickly realizes that the artist is sporting designs on more than just a lucrative album deal.

"My character on Boston Public was a little shy," Gray says.

"[Zora] is much more outgoing and aggressive."

Um, just how aggressive are we talking here?

"There are no kissing scenes," laughs Gray.

"That probably would have been my [deal]breaker, because I don't know if I'm ready for it just yet."

When Gray is not pursuing girls, er, acting gigs, she's busy putting the finishing touches on her debut album, which is due out in the spring.

"For the most part, I will have written most of my album except for one song," says the Maryland native, who describes the CD as "a blend of old school and new school, with alternative pop and R&B."

And if Gray has it her way, her album's release will coincide with another big career development.

"Hopefully by the time my album is about to drop, then I'll be back on Boston Public," she says with a smile, "because [my character] ended with a record deal.

Sounds like Gray may have a future in marketing, too.

Milo Ventimiglia: Neither Bad Nor a Boy -

"My manager makes fun of me," says Milo Ventimiglia.

"He's like, 'Since you started in the business, you've aged eight years, but on television, you've only aged two or three.'

10.1.03 - NBC is looking at a sitcom with Michael Rapaport, currently titled First Comes Love, which was also written by Rapaport along with Les Firestein, according to the Hollywood Reporter.

9.23.03 - Variety reports that David E. Kelley will be writing a big-screen remake of Agatha Christie's classic mystery "Witness for the Prosecution."

Anxious to maintain its audience after a move to Friday night, David E. Kelley's "Boston Public" is filling up with guest stars like so many over-crowded public school classrooms.

Dennis Miller was already slated to begin a multi-episode arc on Friday, Oct. 24 and he'll be joined by former "Twin Peaks" gal Sherilyn Fenn.

Fenn has signed on to do at least two episodes of the FOX drama, starting with Oct. 24 show....

9.22.03 - Michael Rapaport will be on Last Call with Carson Daly the night of Thursday, September 25th.

Fox has ordered a pilot script for a comedy from David E. Kelley Prods. called Five Finger Discount, according to the Hollywood Reporter.

The script will be penned by Kerry Ehrin, a consulting producer on Boston Public.

Dennis Miller has signed on for a 3-episode arc the will begin Friday, October 24th.

For more information on his role, see the previews page.

8.25.03 - Lyndsy Fonseca (The Young and the Restless) will guest star on three episodes of Boston Public.

8.14.03 - FOX has changed the premiere date of Boston Public from September 26th to Septmeber 19th.

Milo Ventimiglia, who was last seen as Jess on Gilmore Girls will appear in three episodes of Boston Public, Variety reports.

He'll play a bad boy with a hidden agenda.

Kristin at E!Online reports that James Van Der Beek could be headed back to the big screen.

He's in talks to star in "Standing Still," described as a "Big Chill" for Gen Y, which also stars Michael Rapaport and Estella Warren.

'Angel' Brings in Fresh Face, Old Friend -

As the only currently active outpost in the know Buffy-verse, "Angel" is swelling its cast to include even more familiar faces, as well as one or two new characters to replace departed Charisma Carpenter and Vincent Kartheiser.

As has long been rumored, Mercedes McNab will join the show on a recurring basis, revisiting her Harmony character.

This will allow Harmony, a somewhat bumbling vampire whose attempts at self-empowerment rarely end well, to reunite with former flame Spike (James Marsters, who has already been announced as a new series regular).

McNab made appearances as Harmony on both "Buffy the Vampire Slayer" and "Angel."

McNab's other credits include appearances on "Dawson's Creek" and "Boston Public."

The WB has also confirmed that another "Boston Public" alum, Sarah Thompson, will join "Angel" for at least six episodes as Eve, a new assistant to David Boreanaz's Angel at Wolfram & Hart.

Those in the know are coy about Thompson's character, who may or may not provide temptation for the show's undead hero.

Thompson, who played high school seductress Dana Pool in the first season of "Boston Public," appeared on episodes of "The District" and "Touched by an Angel" last season.

She also was in the feature "Malibu's Most Wanted."

7.29.03 - TV Guide Online: Meet Boston Public's "Spicy Latina" -

This fall, Natalia Baron joins the cast of Boston Public as Miss Carmen Torres.

"I'm a spicy Latina student teacher," the newbie tells TV Guide Online.

"She's still in college and she comes in speaking Spanish the whole way, even though she's teaching physics, not Spanish!"

What gives with Carmen livin' la vida loca en Español?

"She believes that all the kids should learn Spanish — as well as all the teachers — because we're fighting in a bilingual job market," Baron smiles.

7.29.03 - FOX has schedule the season premiere of Boston Public for Friday, September 26th.

7.22.03 - From TV Guide Online: Former New Kid Joey McIntyre and That '70s Show's Mila Kunis

are taking the plunge, signing on to star in a big-screen adaptation of the

interactive stage show Tony 'n' Tina's Wedding.

7.17.03 - Boston Public received one Emmy nomination for Outstanding Choreography.

The Emmy Awards will be presented live on Fox from the Los Angeles Shrine Auditorium on Sunday, September 21st.

Tamyra Gray was nominated for a Teen Choice Award as Breakout Female TV Star for her recurring role on Boston Public.

The awards are scheduled to air Wednesday, Aug. 6 on FOX.

Teens can vote on several categories at TeenPeople.com (a subscription is required).

6.3.03 - Couple of program changes coming to Fox's Friday night schedule next month: as of July 11th The Bernie Mac Show will air back to back episodes from 8-9pm and Boston Public moves to 9pm.

As of August 8th, Wanda at Large slides into the 8:30pm time slot, displacing the second Bernie Mac.

5.28.03 - TV Guide gives JEERS to Whitney Houston's unlikely appearance on Fox's Boston Public.

As if it weren't stretching credibility that Houston would play a high school prom, the pop diva further challenged reality by showing up for the gig on time!

5.27.03 - Joey McIntyre, Jon Abrahams, Cara DeLizia and China Jesusita Shavers will not be returning next year.

Bianca Kajlich (Lisa Grier, first season) and Joey Slotnick's new comedy, Rock Me Baby, has been picked up by UPN for the fall season.

Boston Public has been renewed for another season by FOX, but will now be airing on Fridays at 9pm ET.

David E. Kelley's new drama, The Brotherhood of Poland, N.H. (starring, among others, Cleo King, the "smell that shoe" woman), has been picked up by CBS for the fall and will air on Wednesday nights.

5.13.03 - Indigo's (Cheyenne) new cop drama, 10-8, has been picked up for the fall season by ABC, and will air on Sundays at 8pm ET.

5.3.03 - From the May 3rd issue of TV Guide:

It wasn't jealousy over Tamyra Gray's rendition of "I Will Always Love you" that convinced Whitney Houston to play herself in the May 12 season finale of Fox's Boston Public but rather a plea from series creator David E. Kelley.

He phoned Houston and asked if she'd play a student's superstar prom date.

To sweeten the deal, Kelley is letting the diva sing a track from her latest CD.

3.7.03 - Indigo (fka Alyssa Ashley Nichols, who plays Cheyenne) has been signed to play Officer Graves, a trainee at the Sheriff's Dept., in the ABC crime drama 10-8.

Cleo King (the "smell this shoe" woman) has been cast in David E. Kelley's CBS pilot, The Brotherhood of Poland, New Hampshire.

Tamyra Gray Signs for More 'Boston Public' -

Former "American Idol" contestant Tamyra Gray has received an extended hall pass from the producers of "Boston Public."

Gray has signed to appear in three more episodes of the FOX drama, bringing her total to seven.

She made her prime-time acting debut on Monday's (Feb. 24) episode of the series.

"We are extremely excited about the acting debut of Tamyra Gray," executive producer Jason Katims says.

"She has done an amazing job in portraying a sensitive character...."

Tonight's Boston Public revolves around a closeted teen named Devon who comes to terms with his same-sex feelings after witnessing a gay bashing.

There's just one problem – Matt Lutz, the actor playing Devon, is about as pro-gay as Jesse Helmes.

"I think homosexuality is a sin," the conservative Christian tells The Advocate.

"I think that it is a lifestyle that I don't necessarily...

Tamyra Gray Sings Her Heart Out for 'Boston Public' -

Since losing out to Kelly Clarkson in the first season of FOX's "American Idol," 23-year-old Tamyra Gray has gone on to prove that, sometimes, winning isn't about coming first.

A favorite of the show's judges -- in particular the acerbic Simon Cowell -- Gray has now embarked on an acting career, with a four-episode stint (and perhaps more) on FOX's high-school drama "Boston Public...."

Writers Guild To Honor David E. Kelley, John Gay -

The Writers Guild of America, west (WGAw) will honor John Gay and David E. Kelly with awards for excellence.

The awards will be presented at the 55th Annual Writers Guild Award ceremony on March 8, 2003....

10.14.02 - Jeri Ryan was #41 on TV Guide's list of the 50 Sexiest Stars of All Time.

Of all the wonders of the sci-fi universe, few compare to Seven of Nine (1997-2001) in UPN's Star Trek: Voyager.

Only Jeri Ryan could have made this icy Borg such a voluptuous, red-blooded woman.

In a catsuit so tight it must have made breathing difficult, Ryan could always be counted on to heat up the cold vacuum of outer space.

'Idol' Contestant Gray Enrolls in 'Boston Public' -

"American Idol's" assault on the world of entertainment continues.

The latest salvo comes in the form of Tamyra Gray, "Idol's" fourth-place finisher.

She'll be appearing on several episodes of FOX's "Boston Public" beginning in February.

"We're thrilled to have Tamyra join the cast for four episodes later this season," executive producer Jason Katims says.

"She gave a very impressive audition, and while it's possible her character will sing, we are most interested in helping to launch her as a dramatic actress...."

Fox is confirming that American Idol standout Tamyra Gray will appear in four episodes of Boston Public beginning in February.

American Idol loser Tamyra Gray may prove to be the show's biggest winner after all.

The up-and-comer is in talks to join the cast of Boston Public for a multi-episode arc.

If a deal is finalized, Gray -- who landed a record contract with the producers behind Idol -- could debut by November sweeps.

David E. Kelley is stepping down as executive producer and

head writer of Fox's Boston Public in order to focus his attention on ABC's The

Practice and his new Fox drama, girls club.

will replace him behind-the-scenes -- which may mean that aliens are about to

Boston Public's New Kid on the Block - Fresh from doing tick, tick...

off Broadway, Joey McIntyre has moved to L.A. to join the cast of Boston Public.

It's a culture shock for the New Kids on the Block star to leave his beloved Boston for the Santa Monica beach.

But hey, he still gets to play a Beantown boy on TV....

7.22.02 - Boston Public will have its third season premiere on Monday, October 21st at 8pm ET.

7.17.02 - TV Guide Online: Halloween's New Ghoul Girl - Could Halloween: Resurrection boost unknown Bianca Kajlich to full-fledged starlet status?

So far, she's done perky pom-pom duty as a cheerleader in Bring It On.

Plus, she spent a year on Boston Public as Lisa...

7.10.02 - Jon Abrahams (Scary Movie, Meet the Parents) will be joining the cast as a new faculty member.

6.7.02 - Former New Kids on the Block singer Joey McIntyre will be guest starring next fall.

5.30.02 - David E. Kelley is in the process of casting one or more male teachers for Boston Public.

FOX unveiled their official fall schedule today, and Boston Public will be keeping its 8pm ET Monday time slot, followed by David E. Kelley's new show, Girls Club.

5.6.02 - Chicago Sun-Times: A 'Public' role with principles -

It was two years ago this month, in a Manhattan theater packed with ad execs, that Fox first trotted out "Ally McBeal" and "The Practice" auteur David E. Kelley along with the cast of his new high school drama for the following fall....

4.29.02 - FOX has officially renewed Boston Public for a third season.

4.24.02 - Don't miss Nicky Katt in the new movie, "Insomnia," in theaters everywhere May 24th.

4.1.02 - Girls Club, a new pilot for FOX from David E. Kelley, has cast Giancarlo Esposito as its first cast member.

Esposito will play a senior partner at the law firm headed and owned by three women attorneys.

3.30.02 - TV Guide mentions Michael Rapaport in "Great Performances" on page 10 of the March 30th issue.

As Danny Hanson, the brash and boyish new teacher on Fox's Boston Public, Michael Rapaport earns an A for attitude.

Although Danny is reckless and impishly confrontational–he urged his students to sue a fellow teacher for defamation of character–Rapaport's working-class charm keeps the chracter blissfully free of the mannered quirks that define so much of the faculty.

He was quite moving in a recent episode in which he defied authority and risked his career by analyzing the racially charged N-word during classroom "talk time."

By not being afraid to show that Danny doesn't have all the answers, Rapaport moves to the head of his class.

3.13.02 - Bianca Kajlich (Lisa Grier) has been cast in the WB sitcom In My Opinion, along with Nat Faxon, Richard Trapp, Stacy Francis, and Peter McKenzie.

3.12.02 - Thomas McCarthy (Coach Kevin Riley) can currently be seen in the Broadway production of "Noises Off."

Chi McBride is named one of TV's MVP actors in the March 9th issue of TV Guide.

At 6-foot-5, McBride is an automatic authority figure, whether battling racial unjustice, policing horny faculty members or impersonating Ralph Kramden in a play.

"He brings enormous weight to the series, and I don't mean this as a pun," says Anthony Heald, who plays administrator Scott Guber.

"His character has an enormous heart and a very strong set of priciples.

2.13.02 - Fox has given a 13 episode commitment to a new David E. Kelley drama focusing on three women (guess what? they're lawyers!) who live together in San Francisco.

2.7.02 - Zap2It.com: Advocacy Groups Target 'Boston Public' -

A coalition of 15 family and child advocacy groups have sent the Federal Communications Commission a letter complaining that FOX's "Boston Public's" is too racy for the eight o'clock hour....

12.18.01 - Chi McBride has been nominated for an American Film Institute Award for AFI Male Actor of the Year in a Series.

The awards ceremony will be broadcast on CBS on Saturday, January 5th, at 8pm ET.

Loretta Devine has been nominated for two NAACP Image awards.

One is for her supporting role in the motion picture "Kingdom Come" and the other is for Oustanding Actress in a Drama Series.

Rashida Jones and Vanessa Bell Calloway also received nominations for Outstanding Supporting Actress in a Drama Series.

Boston Public itself received a nomination for Outstanding Drama Series.

The awards will be presented on February 23rd in Los Angeles.

Boston Public gets Jeers in the November 17th issue of TV Guide.

The hiring of actress Jeri Ryan by executive producer David E. Kelley to spice of Fox's Boston Public all but guaranteed an endless supply of tawdry double entendres.

And the only disappointment in Ryan's first episode on October 29 was that the entendres didn't even aspire to the level of double.

Kelley, who seems increasingly incapable of creating female characters who are not miniskirted sexpots, gave Ryan a truly inauspicious welcome.

In one commercial for the series, Ryan, as teacher Ronnie Cooke, was asked by an inquisitive student whether she was a "a real teacher."

Her response–"Yes, are you a real student?"– was only slightly wittier than "I know you are, but what am I?"

But the real indignity came when, in Ryan's first episode, a student asked to see her breasts.

We've seen old Van Halen videos with more class.

David E. Kelley is developing a new series for Fox, but he's not writing it.

The new show is called The Understudy and will be supervised and exec prod by Kelley, produced via David E. Kelley Prods. and 20th.

But he won't be writing the pilot or any of the presumed subsequent episodes.

That task will be left to Ivan Menchell, current writer/producer on Ally McBeal.

Along with Menchell, The Understudy was co-created by Bill D'Elia who is also the showrunner on Ally, and will direct The Understudy.

The show is about a 21 year old in NYC trying to make a career for herself on Broadway.

10.31.01 - TV Guide Online reports that Fox's Monday night dramas returned to mixed results: Boston Public debuted strongly with 13.8 million viewers, but Ally McBeal

averaged a disappointing 10.8 million viewers.

10.30.01 - Don't miss the full-length article in the October 27th issue of TV Guide on new cast member Jeri Ryan.

The November 6th issue of Soap Opera Digest reports that Sharon Leal and fiancé Bev Land welcomed their first child, Kai Miles Land, into the world on September 13th.

9.9.01 - Boston Public won one Creative Arts Emmy for Outstanding Art Direction for a Single-Camera Series ("Chapter One").

8.6.01 - TV Guide Online: Jeri Ryan's New Boss -

When Boston Public begins its sophomore year this September, Winslow High's male pupils won't be the only ones ogling former Star Trek: Voyager bombshell Jeri Ryan - who's enrolling as curvaceous corporate-lawyer-turned-teacher Ronnie Brooks...

7.12.01 - Boston Public received 2 Emmy nominations including Outstanding Art Direction for a Single-Camera Series ("Chapter One") and Outstanding Guest Actress in a Drama Series (Kathy Baker as Mrs. Peters).

The June 19th issue of Soap Opera Digest reports that Sharon Leal is pregnant.

Although in the past, she had been linked with Grayson McCouch (Another World, All Souls), with whom she worked on Legacy, sources indicate that the child is not his.

5.8.01 - TV Guide gives Jeers to spelling trouble.

"We'd like to think the April 16 episode of Fox's Boston Public was making a sly comment about the state of American education, but we suspect plain old carelessness was the culprit.

During a conversation between teachers Harry and Lauren, a chalkboard in the background listed the day's assignment.

Boston Public has received a Prism Commendation for the episode "Chapter Eight."

Prism recognizes work in which members of the entertainment community take an active role in addressing drug abuse in America.

The 5th annual Prism awards, hosted by Jamie Lee Curtis and Richard Lewis, were taped April 4th.

No word yet when or where they will air.

3.8.01 - At the TV Guide Awards, which aired on Fox last night, Peter MacNicol, Chi McBride and Lara Flynn Boyle presented the first annual Brandon Tartikoff Award to David E. Kelley for incredible achievement in television.

3.6.01 - Zap2It.com: Boston Public Hits Close to Home

3.5.01 - TV Guide Online: Boston Public Star Stands Tall - Chi McBride takes great pride in his role as formidable principal Steven Harper...

2.10.01 - Chi McBride was named one of the MVP actors of TV in the February 10th issue of TV Guide.

In addition, David E. Kelley was named one of the MVP writers of TV.

David E. Kelley will take home the newly minted Brandon Tartikoff Award at the third annual TV Guide Awards, which will air on March 7 on Fox.

Named for the legendary network executive, Tartikoff's award honors other creative movers and shakers behind the scenes.

Fox has renewed "Boston Public" for a second year, giving it a full season order.

"Boston Public" has earned to date an average of 12.1 million viewers, a 5.6 among A18-49, and the show's audience has been building.

After the November sweep when repeats became regular fare on the competing networks, the opportunity came to much of the audience to see "Boston Public" for the first time.

Now the question is how many are hooked and will stay hooked through the February sweep.

12.29.00 - "Boston Public" has been nominated for two TV Guide Awards: New Series of the Year and Actor of the Year in a New Series (Chi McBride).

11.30.00 - "Boston Public" was nominated for a People's Choice Award as Favorite New Television Dramatic Series.

11.4.00 - Matt Roush in the November 4th issue of TV Guide: "I'm the principal.

I'm entitled to a tone," says the formidable Chi McBride as Steven Harper, the exasperated yet dedicated principal on Fox's high school melodrama Boston Public.

McBride, best known for comedy (including UPN's notorious The Secret Diary of Desmond Pfeiffer), sets the dramatic tone for this often over-the-top series, projecting a powerful aura of quiet, steely authority, even when his fractious faculty and rebellious students wear him down.

Both rational and explosive, McBride's Harper is a stern general who nonetheless inspires loyalty among his troops.

In this role, McBridge shows he's an actor of, yes, principle.

Dania dated "Soul Plane" director Jessy Terrero until 2008. She became engaged in September 2011 to director John Beverly "Bev" Land. The couple married on the beach in Punta Cana, Dominican Republic on February 16, 2013. Land has a son Kai (b. 2001).


(meta data) TITLE: Bullied as a Kid, This Founder Now Runs a $5 Billion Company. Here's What He's Doing to Help Others.

(meta data) PUBLISHER: https://www.facebook.com/EntMagazine

(meta data) COPYRIGHT: Copyright 2019 Entrepreneur Media, Inc. All rights reserved.

(meta data) PUBLISHED DATETIME: 2016-10-20 13:30:00

# Bullied as a Kid, This Founder Now Runs a $5 Billion Company.

Andrew Nikou built his career using innovative thinking to turn around distressed and neglected companies.

Now he turns his attentions toward solving a problem with a global scale: bullying.

Born to Iranian immigrants, Andrew Nikou grew up outside of Los Angeles, where his dad worked in the city's water and power department.

The family didn't have a lot of money, and Nikou was the target of harsh bullying in elementary and middle school.

"I was shorter than most of the guys," Nikou told Entrepreneur, "And that bullying had a traumatic effect on me."

With the guidance of his father, Nikou was able to take control of the situation and ultimately turned that trauma into a great motivator.

"My father let me believe that strength wasn't a physical matter, it was an intellectual matter and that allowed me to pave the way to focus on the competitive side of me," he says.

Related: Use These Green Beret Tactics to Shut Down a Meeting Bully

Once that fuse was lit, Nikou's mind for business took off.

"When I was younger, I started trading baseball and basketball cards and began making a lot of money," he says.

"When people asked what I wanted to be, I said a CEO.

They'd say CEO of what kind of business and I said, 'I don't know, I just want to be a CEO!'"

Nikou was able to rise above his family's tough economic status, went to college, and in 2005, founded OpenGate Capital, a global private equity firm that has amassed $5 billion in total revenues over the firm's 11-year history.

The founder spoke with Entrepreneur about his path to success and the initiative he is leading to help others escape the hopelessness brought about by bullying in school and in the workplace.

Related: Don't Read This! (It's Only the Most Valuable Psychology Hack You Can Learn)

"The problem of bullying is something that is deep in my heart from the experience that I had growing up back in Woodland Hills.

I experienced it mostly on the playground, and it left me feeling defeated.

It was tough and it was embarrassing, to be honest.

So I want to find new innovative ways to confront the bullying challenges we face in classrooms and the workplace, and then, of course, cyberbullying.

"I want to give people the support they need to pivot away from the psychological and physical trauma and build from a positive place of strength."

"This anti-bullying initiative I'm exploring is a collaboration between my charitable organization, The Andrew Nikou Foundation, and XPRIZE, where I am on the Innovation Board.

We have some of the greatest minds in many industries -- Elon Musk and Larry Page, to name a few.

XPRIZE is trying to use crowdsourcing and incentivizing prizes to solve some of the planet's grandest problems in fields like education, health and technology.

"I'm going to be the sponsor of the prize.

We will put this challenge out to teams, and invite them to present their approaches and projects to the board.

The winner of that will receive an incentive prize, which can range in the millions.

Related: 9 Iconic Inventors Who Changed the World

You can imagine that this problem requires something other than a traditional solution.

You're not going to get a bunch of people in a classroom and tell them to read something and say this isn't the right way of behaving.

We need more of a disruptive, a more exponential approach to changing the way people behave.

Some of the concepts would surely include VR, taking kids and adults who are bullying and putting them in VR settings where they can experience what it feels like to be bullied."

"My father's teaching helped me through those tough times when I was a kid.

He taught me to be scrappy and smart, to use my brain rather than my muscles.

He retired early at a very low pay rate so that we could qualify to get grants to go to college.

His income was so low at that point that he had to move back to Iran in order to support himself.

That was another huge motivator for me to overachieve."

Related: 7 Tips For a Thriving, Sustainable Family Business That Lasts

"When we moved to Los Angeles, we became friends with people in the Iranian community and that helped build my confidence and made me stronger.

I never felt short with my friends -- in fact, I often felt like I was the tallest guy in the room.

The loyalty and love I felt from this group, which we called The Persian Pride, rolled into high school and we stayed tight.

They were actually the first people to invest in my first deal a decade later.

A lot of all this is implanted in the culture of my firm.

Loyalty is the number one most important thing for me."

Related: 12 Low-Cost Business Ideas for Introverts

"When I was a teenager, I wanted to go out with a group of my friends to the movies and my father insisted that I stay home and focus on my studies.

We got in the biggest fight that night, but he was insistent.

So I stayed home and later that night, some of my friends were gunned down in a drive-by shooting.

Several were hit, and one of my best friends was killed.

I wouldn't be here now if it wasn't for my father."

"In business, I try to understand where other people are coming from.

I try to understand their position, where they came from, what their history is, who their family is.

Once you get to a humanistic level, you can really start to see what the truth is.

Sure there is a give and take in every negotiation, but I don't believe that there doesn't have to be a 'winner' and a 'loser.'

Related: 25 Inspiring Entrepreneurs Under 40

"All of what we're doing, money is just a byproduct.

It is important to me that we're not just taking, but that we're giving back.

I'm 39, relatively young, so my goal is to look back and not just see that OpenGate was a bunch of financial products, but human products.

I want to be the guy they recognize when they talk about anti-bullying."

New York Times bestselling author Nicole Lapin can help you pitch your brand to press and strengthen your media training.

Entrepreneur Insider is your all-access pass to the skills, experts, and network you need to get your business off the ground—or take it to the next level.

Are you paying too much for business insurance?

Do you have critical gaps in your coverage?

Trust Entrepreneur to help you find out.

### Entrepreneur Voices on Company Culture

### Entrepreneur Voices on Strategic Management

### Entrepreneur Voices on Effective Leadership

Entrepreneur members get access to exclusive offers, events and more.

Yes, I want to receive the Entrepreneur newsletter.

I agree to the Entrepreneur Privacy Policy and Terms of Use.

### How Agile Leaders Help Organizations Thrive

### 3 Things Drew Barrymore Taught Me About Entrepreneurship

### 9 Ways to Handle Job-Related Stress From Dawn to Dusk

### 4 Science-Backed Ways to Prevent Burnout

Nikou was born in 1977 in Vancouver, British Columbia. His parents left their native Tehran before the Iranian Revolution and relocated to Canada, later moving with Nikou to California when he was four years old. His father, who majored in mathematics at a German university, worked at the Los Angeles Department of Water and Power. Nikou grew up with a passion for trading baseball cards and competing in breakdancing competitions.


The reason he was bullied was because he was short.

(meta data) TITLE: Bullied as a Kid, This Founder Now Runs a $5 Billion Company. Here's What He's Doing to Help Others.

(meta data) PUBLISHER: https://www.facebook.com/EntMagazine

(meta data) COPYRIGHT: Copyright 2019 Entrepreneur Media, Inc. All rights reserved.

(meta data) PUBLISHED DATETIME: 2016-10-20 13:30:00

# Bullied as a Kid, This Founder Now Runs a $5 Billion Company.

Andrew Nikou built his career using innovative thinking to turn around distressed and neglected companies.

Now he turns his attentions toward solving a problem with a global scale: bullying.

Born to Iranian immigrants, Andrew Nikou grew up outside of Los Angeles, where his dad worked in the city's water and power department.

The family didn't have a lot of money, and Nikou was the target of harsh bullying in elementary and middle school.

"I was shorter than most of the guys," Nikou told Entrepreneur, "And that bullying had a traumatic effect on me."

With the guidance of his father, Nikou was able to take control of the situation and ultimately turned that trauma into a great motivator.

"My father let me believe that strength wasn't a physical matter, it was an intellectual matter and that allowed me to pave the way to focus on the competitive side of me," he says.

Related: Use These Green Beret Tactics to Shut Down a Meeting Bully

Once that fuse was lit, Nikou's mind for business took off.

"When I was younger, I started trading baseball and basketball cards and began making a lot of money," he says.

"When people asked what I wanted to be, I said a CEO.

They'd say CEO of what kind of business and I said, 'I don't know, I just want to be a CEO!'"

Nikou was able to rise above his family's tough economic status, went to college, and in 2005, founded OpenGate Capital, a global private equity firm that has amassed $5 billion in total revenues over the firm's 11-year history.

The founder spoke with Entrepreneur about his path to success and the initiative he is leading to help others escape the hopelessness brought about by bullying in school and in the workplace.

Related: Don't Read This! (It's Only the Most Valuable Psychology Hack You Can Learn)

"The problem of bullying is something that is deep in my heart from the experience that I had growing up back in Woodland Hills.

I experienced it mostly on the playground, and it left me feeling defeated.

It was tough and it was embarrassing, to be honest.

So I want to find new innovative ways to confront the bullying challenges we face in classrooms and the workplace, and then, of course, cyberbullying.

"I want to give people the support they need to pivot away from the psychological and physical trauma and build from a positive place of strength."

"This anti-bullying initiative I'm exploring is a collaboration between my charitable organization, The Andrew Nikou Foundation, and XPRIZE, where I am on the Innovation Board.

We have some of the greatest minds in many industries -- Elon Musk and Larry Page, to name a few.

XPRIZE is trying to use crowdsourcing and incentivizing prizes to solve some of the planet's grandest problems in fields like education, health and technology.

"I'm going to be the sponsor of the prize.

We will put this challenge out to teams, and invite them to present their approaches and projects to the board.

The winner of that will receive an incentive prize, which can range in the millions.

Related: 9 Iconic Inventors Who Changed the World

You can imagine that this problem requires something other than a traditional solution.

You're not going to get a bunch of people in a classroom and tell them to read something and say this isn't the right way of behaving.

We need more of a disruptive, a more exponential approach to changing the way people behave.

Some of the concepts would surely include VR, taking kids and adults who are bullying and putting them in VR settings where they can experience what it feels like to be bullied."

"My father's teaching helped me through those tough times when I was a kid.

He taught me to be scrappy and smart, to use my brain rather than my muscles.

He retired early at a very low pay rate so that we could qualify to get grants to go to college.

His income was so low at that point that he had to move back to Iran in order to support himself.

That was another huge motivator for me to overachieve."

Related: 7 Tips For a Thriving, Sustainable Family Business That Lasts

"When we moved to Los Angeles, we became friends with people in the Iranian community and that helped build my confidence and made me stronger.

I never felt short with my friends -- in fact, I often felt like I was the tallest guy in the room.

The loyalty and love I felt from this group, which we called The Persian Pride, rolled into high school and we stayed tight.

They were actually the first people to invest in my first deal a decade later.

A lot of all this is implanted in the culture of my firm.

Loyalty is the number one most important thing for me."

Related: 12 Low-Cost Business Ideas for Introverts

"When I was a teenager, I wanted to go out with a group of my friends to the movies and my father insisted that I stay home and focus on my studies.

We got in the biggest fight that night, but he was insistent.

So I stayed home and later that night, some of my friends were gunned down in a drive-by shooting.

Several were hit, and one of my best friends was killed.

I wouldn't be here now if it wasn't for my father."

"In business, I try to understand where other people are coming from.

I try to understand their position, where they came from, what their history is, who their family is.

Once you get to a humanistic level, you can really start to see what the truth is.

Sure there is a give and take in every negotiation, but I don't believe that there doesn't have to be a 'winner' and a 'loser.'

Related: 25 Inspiring Entrepreneurs Under 40

"All of what we're doing, money is just a byproduct.

It is important to me that we're not just taking, but that we're giving back.

I'm 39, relatively young, so my goal is to look back and not just see that OpenGate was a bunch of financial products, but human products.

I want to be the guy they recognize when they talk about anti-bullying."

New York Times bestselling author Nicole Lapin can help you pitch your brand to press and strengthen your media training.

Entrepreneur Insider is your all-access pass to the skills, experts, and network you need to get your business off the ground—or take it to the next level.

Are you paying too much for business insurance?

Do you have critical gaps in your coverage?

Trust Entrepreneur to help you find out.

### Entrepreneur Voices on Company Culture

### Entrepreneur Voices on Strategic Management

### Entrepreneur Voices on Effective Leadership

Entrepreneur members get access to exclusive offers, events and more.

Yes, I want to receive the Entrepreneur newsletter.

I agree to the Entrepreneur Privacy Policy and Terms of Use.

### How Agile Leaders Help Organizations Thrive

### 3 Things Drew Barrymore Taught Me About Entrepreneurship

### 9 Ways to Handle Job-Related Stress From Dawn to Dusk

### 4 Science-Backed Ways to Prevent Burnout

Nikou was born in 1977 in Vancouver, British Columbia. His parents left their native Tehran before the Iranian Revolution and relocated to Canada, later moving with Nikou to California when he was four years old. His father, who majored in mathematics at a German university, worked at the Los Angeles Department of Water and Power. Nikou grew up with a passion for trading baseball cards and competing in breakdancing competitions. He was bullied in school.


The boys held the first concert of the tour in Seoul.

(meta data) TITLE: SHINee gears up for third world tour

SHINee performs during its "SHINee World III" Seoul concert at the Olympic Park's Gymnastics Stadium on Sunday.

SM EntertainmentNearly two years since the group's previous world tour, the five members of SHINee are in full swing once again and will be taking their music and performances across borders on their new tour, "SHINee World III."

"We are about to embark on our next world tour and we are very excited to be performing outside of Korea once again," said Min-ho during a press conference held in Gymnastics Stadium at the Seoul Olympic Park on Sunday.

"The performanc for this tour is very upbeat and a lot more engaging compared to our previous ones ...

it's been a long time since we performed a solo concert so we prepared a lot for it."

"We have a lot of new songs that we are performing ... you can think of this show as a SHINee upgrade," Taemin added.

The idol stars kicked off this leg of their third world tour with two live concerts in Olympic Gymnastics Stadium over the weekend.

At the concerts, the members performed in front of a combined audience of approximately 20,000 local and international fans.

Tickets to SHINee's Seoul performances went on sale last month and sold out in less than 15 minutes.

"We were very thankful to our fans after hearing that tickets to the shows were sold out," said Jong-hyun.

"Hearing the news of our shows being sold out really affected the atmosphere while we were practicing for the concert," said Min-ho.

"Knowing this just motivated us to work even harder and to put on a great show to thank our fans."

Starting next month SHINee will be venturing across the globe, performing in the Latin American nations of Mexico, Chile and Argentina for the first time.

The members will also be making a number of stops in Asia, from Taiwan and China to a finale concert in Jakarta, Indonesia, on June 22.

"We have chosen the term 'popcorn' to describe our new concert," said Jong-hyun.

"The reason for this is because, just like the movement of popping corn, we will be energetic and jumping around the stage and enjoying the time with our fans."

During the final Seoul show on Sunday the members of SHINee electrified the group's largely teenaged female fans with 29 songs and more than two hours of onstage choreography and playful antics.

The night included throwback performances of hits such as "Juliet" and "Ring Ding Dong," as well as the group's latest singles from its third studio album, the two-disc "The Misconceptions of Us," and its fifth EP, "Everybody," both released late last year.

By Julie Jackson (juliejackson@heraldcorp.com)

Interview: 'Chameleonlike' Jinu of Winner sometimes obsesses over things

Review: Enjoying Monsta X's LA concert at home in Seoul

[Kpop Herald x TwitterBlueroom] Pentagon prepares for world tour by connecting with global fans

Review: BTS' 'Bring The Soul' delves into blood, sweat and tears of stardom

[Photo News] BTS wins big at 2018 MAMA in Hong Kong

[Photo News] BTS walks red carpet at 2018 MAMA in Japan

[Photo News] Rising stars Stray Kids arrive at 2018 MAMA

[Photo News] BTS posts Twitter selfies after Melon Music Awards victory

[V Report] Fans go wild as Monsta X streams LA concert on V Live

'Avengers of K-pop': SHINee, EXO, NCT members team up in new SM supergroup

[V Report] BTS' Jimin ready for serious workout

Kang Daniel, Jihyo of Twice dating, agencies confirm

[V Report] Is BTS' Jimin writing a song?

[V Report] Blackpink celebrates 3rd anniversary

[V Report] Stray Kids sad to wrap up European tour

Big Hit acquires GFriend's agency Source Music

[V Report] BTS enjoys water sports on rainy day

[V Report] NCT Dream shares Renjun's good news

[V Report] Jennie asks fans advice on her dog's health

[V Report] GOT7 shares moments from global tour

[OH MY ROOKIE] A.C.E proves potential for global success with dynamic charms

[V Report] Monsta X's Hyungwon checks in from Atlanta

[V Report] Seventeen counts down for new digital single


(meta data) TITLE: SHINee gears up for third world tour

SHINee performs during its "SHINee World III" Seoul concert at the Olympic Park's Gymnastics Stadium on Sunday.

SM EntertainmentNearly two years since the group's previous world tour, the five members of SHINee are in full swing once again and will be taking their music and performances across borders on their new tour, "SHINee World III."

"We are about to embark on our next world tour and we are very excited to be performing outside of Korea once again," said Min-ho during a press conference held in Gymnastics Stadium at the Seoul Olympic Park on Sunday.

"The performanc for this tour is very upbeat and a lot more engaging compared to our previous ones ...

it's been a long time since we performed a solo concert so we prepared a lot for it."

"We have a lot of new songs that we are performing ... you can think of this show as a SHINee upgrade," Taemin added.

The idol stars kicked off this leg of their third world tour with two live concerts in Olympic Gymnastics Stadium over the weekend.

At the concerts, the members performed in front of a combined audience of approximately 20,000 local and international fans.

Tickets to SHINee's Seoul performances went on sale last month and sold out in less than 15 minutes.

"We were very thankful to our fans after hearing that tickets to the shows were sold out," said Jong-hyun.

"Hearing the news of our shows being sold out really affected the atmosphere while we were practicing for the concert," said Min-ho.

"Knowing this just motivated us to work even harder and to put on a great show to thank our fans."

Starting next month SHINee will be venturing across the globe, performing in the Latin American nations of Mexico, Chile and Argentina for the first time.

The members will also be making a number of stops in Asia, from Taiwan and China to a finale concert in Jakarta, Indonesia, on June 22.

"We have chosen the term 'popcorn' to describe our new concert," said Jong-hyun.

"The reason for this is because, just like the movement of popping corn, we will be energetic and jumping around the stage and enjoying the time with our fans."

During the final Seoul show on Sunday the members of SHINee electrified the group's largely teenaged female fans with 29 songs and more than two hours of onstage choreography and playful antics.

The night included throwback performances of hits such as "Juliet" and "Ring Ding Dong," as well as the group's latest singles from its third studio album, the two-disc "The Misconceptions of Us," and its fifth EP, "Everybody," both released late last year.

By Julie Jackson (juliejackson@heraldcorp.com)

Interview: 'Chameleonlike' Jinu of Winner sometimes obsesses over things

Review: Enjoying Monsta X's LA concert at home in Seoul

[Kpop Herald x TwitterBlueroom] Pentagon prepares for world tour by connecting with global fans

Review: BTS' 'Bring The Soul' delves into blood, sweat and tears of stardom

[Photo News] BTS wins big at 2018 MAMA in Hong Kong

[Photo News] BTS walks red carpet at 2018 MAMA in Japan

[Photo News] Rising stars Stray Kids arrive at 2018 MAMA

[Photo News] BTS posts Twitter selfies after Melon Music Awards victory

[V Report] Fans go wild as Monsta X streams LA concert on V Live

'Avengers of K-pop': SHINee, EXO, NCT members team up in new SM supergroup

[V Report] BTS' Jimin ready for serious workout

Kang Daniel, Jihyo of Twice dating, agencies confirm

[V Report] Is BTS' Jimin writing a song?

[V Report] Blackpink celebrates 3rd anniversary

[V Report] Stray Kids sad to wrap up European tour

Big Hit acquires GFriend's agency Source Music

[V Report] BTS enjoys water sports on rainy day

[V Report] NCT Dream shares Renjun's good news

[V Report] Jennie asks fans advice on her dog's health

[V Report] GOT7 shares moments from global tour

[OH MY ROOKIE] A.C.E proves potential for global success with dynamic charms

[V Report] Monsta X's Hyungwon checks in from Atlanta

[V Report] Seventeen counts down for new digital single

The boys held the first concert of the tour in Seoul.


(meta data) TITLE: SHINee gears up for third world tour

SHINee performs during its "SHINee World III" Seoul concert at the Olympic Park's Gymnastics Stadium on Sunday.

SM EntertainmentNearly two years since the group's previous world tour, the five members of SHINee are in full swing once again and will be taking their music and performances across borders on their new tour, "SHINee World III."

"We are about to embark on our next world tour and we are very excited to be performing outside of Korea once again," said Min-ho during a press conference held in Gymnastics Stadium at the Seoul Olympic Park on Sunday.

"The performanc for this tour is very upbeat and a lot more engaging compared to our previous ones ...

it's been a long time since we performed a solo concert so we prepared a lot for it."

"We have a lot of new songs that we are performing ... you can think of this show as a SHINee upgrade," Taemin added.

The idol stars kicked off this leg of their third world tour with two live concerts in Olympic Gymnastics Stadium over the weekend.

At the concerts, the members performed in front of a combined audience of approximately 20,000 local and international fans.

Tickets to SHINee's Seoul performances went on sale last month and sold out in less than 15 minutes.

"We were very thankful to our fans after hearing that tickets to the shows were sold out," said Jong-hyun.

"Hearing the news of our shows being sold out really affected the atmosphere while we were practicing for the concert," said Min-ho.

"Knowing this just motivated us to work even harder and to put on a great show to thank our fans."

Starting next month SHINee will be venturing across the globe, performing in the Latin American nations of Mexico, Chile and Argentina for the first time.

The members will also be making a number of stops in Asia, from Taiwan and China to a finale concert in Jakarta, Indonesia, on June 22.

"We have chosen the term 'popcorn' to describe our new concert," said Jong-hyun.

"The reason for this is because, just like the movement of popping corn, we will be energetic and jumping around the stage and enjoying the time with our fans."

During the final Seoul show on Sunday the members of SHINee electrified the group's largely teenaged female fans with 29 songs and more than two hours of onstage choreography and playful antics.

The night included throwback performances of hits such as "Juliet" and "Ring Ding Dong," as well as the group's latest singles from its third studio album, the two-disc "The Misconceptions of Us," and its fifth EP, "Everybody," both released late last year.

By Julie Jackson (juliejackson@heraldcorp.com)

Interview: 'Chameleonlike' Jinu of Winner sometimes obsesses over things

Review: Enjoying Monsta X's LA concert at home in Seoul

[Kpop Herald x TwitterBlueroom] Pentagon prepares for world tour by connecting with global fans

Review: BTS' 'Bring The Soul' delves into blood, sweat and tears of stardom

[Photo News] BTS wins big at 2018 MAMA in Hong Kong

[Photo News] BTS walks red carpet at 2018 MAMA in Japan

[Photo News] Rising stars Stray Kids arrive at 2018 MAMA

[Photo News] BTS posts Twitter selfies after Melon Music Awards victory

[V Report] Fans go wild as Monsta X streams LA concert on V Live

'Avengers of K-pop': SHINee, EXO, NCT members team up in new SM supergroup

[V Report] BTS' Jimin ready for serious workout

Kang Daniel, Jihyo of Twice dating, agencies confirm

[V Report] Is BTS' Jimin writing a song?

[V Report] Blackpink celebrates 3rd anniversary

[V Report] Stray Kids sad to wrap up European tour

Big Hit acquires GFriend's agency Source Music

[V Report] BTS enjoys water sports on rainy day

[V Report] NCT Dream shares Renjun's good news

[V Report] Jennie asks fans advice on her dog's health

[V Report] GOT7 shares moments from global tour

[OH MY ROOKIE] A.C.E proves potential for global success with dynamic charms

[V Report] Monsta X's Hyungwon checks in from Atlanta

[V Report] Seventeen counts down for new digital single

The boys held the first concert of the tour in Seoul. The concert was on the 8th and 9th.


He was wounded in the face by rifle fire.

(meta data) TITLE: Philippe Lançon, PLAS Visting Fellow for AY15, Injured in the Paris Terrorist Attack | Program in Latin American Studies (PLAS)

# Program in Latin American Studies (PLAS)

## A blog about our intellectual and cultural programs, students, and faculty.

# Philippe Lançon, PLAS Visting Fellow for AY15, Injured in the Paris Terrorist Attack

Posted on January 8, 2015 by Eneida Toner

Philippe Lançon, a journalist specializing in Cuba and Latin America who is on staff at Libération, was gravely injured yesterday during the terrorist attack at Charlie Hebdo in Paris.

Philippe was attending an editorial team meeting when the two gunmen broke into the room and opened fire.

He is now in intensive care at a Paris hospital, where he is listed in critical but stable condition.

Philippe has been involved with PLAS since 2012.

He has been a guest speaker at some of our courses, attended our events, and he was recently selected as a visiting fellow for next year.

His plan was to spend the fall semester in Princeton, teaching a course on "Writers and Dictators in Latin America" and researching a new book on Cuba.

Philippe has reported extensively on Latin American culture and literature.

He is one of the most serious critics of Latin American literature in Paris and he has published extensive interviews with many writers, including Jorge Edwards and Mario Vargas Llosa.

Recently, Philippe had been covering the developments in Cuba.

His last published article is an interview with visual artist Tania Bruguera after she was detained in Havana.

As members of the Princeton community we should do everything we can to show our support for Philippe during these difficult moments.

If you want to write him a note, a postcard, or a letter, please drop it off at the PLAS office and we will send it to him by express mail.

If you prefer to use e-mail, you can address it to plas@princeton.edu; we will print it out and include it in the package.

I will post more news as soon as I can speak to Philippe, after he leaves the intensive care unit.

## 1 thought on "Philippe Lançon, PLAS Visting Fellow for AY15, Injured in the Paris Terrorist Attack"

Your email address will not be published.

'Forbearance as Redistribution': Holland explores legality and politics in Latin America

Rock stars: Exploring the ruins and royalty of ancient Maya courts

Lançon was attending a weekly meeting of "Charlie Hebdo" at the time of the attack on 7 January 2015.


(meta data) TITLE: Philippe Lançon, PLAS Visting Fellow for AY15, Injured in the Paris Terrorist Attack | Program in Latin American Studies (PLAS)

# Program in Latin American Studies (PLAS)

## A blog about our intellectual and cultural programs, students, and faculty.

# Philippe Lançon, PLAS Visting Fellow for AY15, Injured in the Paris Terrorist Attack

Posted on January 8, 2015 by Eneida Toner

Philippe Lançon, a journalist specializing in Cuba and Latin America who is on staff at Libération, was gravely injured yesterday during the terrorist attack at Charlie Hebdo in Paris.

Philippe was attending an editorial team meeting when the two gunmen broke into the room and opened fire.

He is now in intensive care at a Paris hospital, where he is listed in critical but stable condition.

Philippe has been involved with PLAS since 2012.

He has been a guest speaker at some of our courses, attended our events, and he was recently selected as a visiting fellow for next year.

His plan was to spend the fall semester in Princeton, teaching a course on "Writers and Dictators in Latin America" and researching a new book on Cuba.

Philippe has reported extensively on Latin American culture and literature.

He is one of the most serious critics of Latin American literature in Paris and he has published extensive interviews with many writers, including Jorge Edwards and Mario Vargas Llosa.

Recently, Philippe had been covering the developments in Cuba.

His last published article is an interview with visual artist Tania Bruguera after she was detained in Havana.

As members of the Princeton community we should do everything we can to show our support for Philippe during these difficult moments.

If you want to write him a note, a postcard, or a letter, please drop it off at the PLAS office and we will send it to him by express mail.

If you prefer to use e-mail, you can address it to plas@princeton.edu; we will print it out and include it in the package.

I will post more news as soon as I can speak to Philippe, after he leaves the intensive care unit.

## 1 thought on "Philippe Lançon, PLAS Visting Fellow for AY15, Injured in the Paris Terrorist Attack"

Your email address will not be published.

'Forbearance as Redistribution': Holland explores legality and politics in Latin America

Rock stars: Exploring the ruins and royalty of ancient Maya courts

Lançon was attending a weekly meeting of "Charlie Hebdo" at the time of the attack on 7 January 2015. He was wounded in the face by rifle fire.


(meta data) TITLE: Philippe Lançon, PLAS Visting Fellow for AY15, Injured in the Paris Terrorist Attack | Program in Latin American Studies (PLAS)

# Program in Latin American Studies (PLAS)

## A blog about our intellectual and cultural programs, students, and faculty.

# Philippe Lançon, PLAS Visting Fellow for AY15, Injured in the Paris Terrorist Attack

Posted on January 8, 2015 by Eneida Toner

Philippe Lançon, a journalist specializing in Cuba and Latin America who is on staff at Libération, was gravely injured yesterday during the terrorist attack at Charlie Hebdo in Paris.

Philippe was attending an editorial team meeting when the two gunmen broke into the room and opened fire.

He is now in intensive care at a Paris hospital, where he is listed in critical but stable condition.

Philippe has been involved with PLAS since 2012.

He has been a guest speaker at some of our courses, attended our events, and he was recently selected as a visiting fellow for next year.

His plan was to spend the fall semester in Princeton, teaching a course on "Writers and Dictators in Latin America" and researching a new book on Cuba.

Philippe has reported extensively on Latin American culture and literature.

He is one of the most serious critics of Latin American literature in Paris and he has published extensive interviews with many writers, including Jorge Edwards and Mario Vargas Llosa.

Recently, Philippe had been covering the developments in Cuba.

His last published article is an interview with visual artist Tania Bruguera after she was detained in Havana.

As members of the Princeton community we should do everything we can to show our support for Philippe during these difficult moments.

If you want to write him a note, a postcard, or a letter, please drop it off at the PLAS office and we will send it to him by express mail.

If you prefer to use e-mail, you can address it to plas@princeton.edu; we will print it out and include it in the package.

I will post more news as soon as I can speak to Philippe, after he leaves the intensive care unit.

## 1 thought on "Philippe Lançon, PLAS Visting Fellow for AY15, Injured in the Paris Terrorist Attack"

Your email address will not be published.

'Forbearance as Redistribution': Holland explores legality and politics in Latin America

Rock stars: Exploring the ruins and royalty of ancient Maya courts

Lançon was attending a weekly meeting of "Charlie Hebdo" at the time of the attack on 7 January 2015. He was wounded in the face by rifle fire. He was left in critical condition.


In 1971, it was transferred to the Smithsonian Institution.

(meta data) TITLE: Apollo 11 Command Module Columbia

A photograph taken inside the Apollo 11 Command Module Columbia shows a map of stowage locations.

#### Michael Collins' Inscription inside Apollo 11 Command Module "Columbia"

Following splashdown,while en route to Hawaii on the USS Hornet, Michael Collins crawled back into the command module (it was connected to the mobile quarantine facility by an air-tight tunnel) and wrote this short note on one of the equipment bay panels.

Spacecraft 107, alias Apollo 11, alias "Columbia.

Excerpt from After Sputnik: 50 Years of the Space Age

The Apollo 11 Command Module Columbia on display at the National Air and Space Museum in Washington, DC.

The Apollo 11 Command Module Columbia on display in the Boeing Milestones of Flight Hall at the National Air and Space Museum in Washington, DC.

On 16 July 1969, American astronauts Neil Armstrong, Edwin "Buzz" Aldrin, and Michael Collins lifted off from Cape Canaveral, Fla., in the mammoth-sized Saturn V rocket on their way to the moon during the Apollo 11 mission.

Cmdr. Armstrong and pilot Aldrin landed the spacecraft, Eagle, on the moon's Sea of Tranquillity.

Apollo 11 booster stages were tested at Stennis Space Center.

The Apollo 11 command module Columbia is displayed at the National Air and Space Museum in Washington, DC.

At 9:32 a.m. EDT, the swing arms move away and a plume of flame signals the liftoff of the Apollo 11 Saturn V space vehicle and astronauts Neil A. Armstrong, Michael Collins and Edwin E. Aldrin, Jr. from Kennedy Space Center Launch Complex 39A.

Apollo 11 Command Module Columbia on temporary cradle.

This object is not on display at the National Air and Space Museum.

The Apollo 11 Command Module, "Columbia," was the living quarters for the three-person crew during most of the first manned lunar landing mission in July 1969.

On July 16, 1969, Neil Armstrong, Edwin "Buzz" Aldrin and Michael Collins were launched from Cape Kennedy atop a Saturn V rocket.

This Command Module, no. 107, manufactured by North American Rockwell, was one of three parts of the complete Apollo spacecraft.

The other two parts were the Service Module and the Lunar Module, nicknamed "Eagle."

The Service Module contained the main spacecraft propulsion system and consumables while the Lunar Module was the two-person craft used by Armstrong and Aldrin to descend to the Moon's surface on July 20.

The Command Module is the only portion of the spacecraft to return to Earth.

It was physically transferred to the Smithsonian in 1971 following a NASA-sponsored tour of American cities.

The Apollo CM Columbia has been designated a "Milestone of Flight" by the Museum.

Do not reproduce without permission from the Smithsonian Institution, National Air and Space Museum

Buzz AldrinMichael CollinsNeil A. Armstrong, 1930 - 2012

Transferred from the National Aeronautics and Space Administration

Primary Materials: Aluminum alloy, Stainless steel, Titanium

National Air and Space Museum Collection

The final leg of the Moon rock's journey to Earth was aboard the command module America, similar to the Apollo 11 command module, Columbia.

On each Apollo mission that landed humans on the Moon (11, 12, 14, 15, and 17), the Lunar module rendezvoused with a command module in lunar orbit.

Neil Armstrong, the first human to walk on the Moon, flew in Columbia as Commander of Apollo 11 and piloted the Museum's X-15.

### Model, Space Shuttle, North American Rockwell Final...

### Rocket Engine, Liquid Fuel, Apollo Lunar Module Descent...

### Space Shuttle Radar Topography Mission Canister, Antenna

### Satellite, Communications, Sirius FM-4

### Gemini Paraglider Research Vehicle 1-A with Wing

The Command Module "Columbia" went on a tour of the United States, visiting 49 state capitals, the District of Columbia, and Anchorage, Alaska.


It was displayed at the National Air and Space Museum (NASM) in Washington, DC.

(meta data) TITLE: Apollo 11 Command Module Columbia

A photograph taken inside the Apollo 11 Command Module Columbia shows a map of stowage locations.

#### Michael Collins' Inscription inside Apollo 11 Command Module "Columbia"

Following splashdown,while en route to Hawaii on the USS Hornet, Michael Collins crawled back into the command module (it was connected to the mobile quarantine facility by an air-tight tunnel) and wrote this short note on one of the equipment bay panels.

Spacecraft 107, alias Apollo 11, alias "Columbia.

Excerpt from After Sputnik: 50 Years of the Space Age

The Apollo 11 Command Module Columbia on display at the National Air and Space Museum in Washington, DC.

The Apollo 11 Command Module Columbia on display in the Boeing Milestones of Flight Hall at the National Air and Space Museum in Washington, DC.

On 16 July 1969, American astronauts Neil Armstrong, Edwin "Buzz" Aldrin, and Michael Collins lifted off from Cape Canaveral, Fla., in the mammoth-sized Saturn V rocket on their way to the moon during the Apollo 11 mission.

Cmdr. Armstrong and pilot Aldrin landed the spacecraft, Eagle, on the moon's Sea of Tranquillity.

Apollo 11 booster stages were tested at Stennis Space Center.

The Apollo 11 command module Columbia is displayed at the National Air and Space Museum in Washington, DC.

At 9:32 a.m. EDT, the swing arms move away and a plume of flame signals the liftoff of the Apollo 11 Saturn V space vehicle and astronauts Neil A. Armstrong, Michael Collins and Edwin E. Aldrin, Jr. from Kennedy Space Center Launch Complex 39A.

Apollo 11 Command Module Columbia on temporary cradle.

This object is not on display at the National Air and Space Museum.

The Apollo 11 Command Module, "Columbia," was the living quarters for the three-person crew during most of the first manned lunar landing mission in July 1969.

On July 16, 1969, Neil Armstrong, Edwin "Buzz" Aldrin and Michael Collins were launched from Cape Kennedy atop a Saturn V rocket.

This Command Module, no. 107, manufactured by North American Rockwell, was one of three parts of the complete Apollo spacecraft.

The other two parts were the Service Module and the Lunar Module, nicknamed "Eagle."

The Service Module contained the main spacecraft propulsion system and consumables while the Lunar Module was the two-person craft used by Armstrong and Aldrin to descend to the Moon's surface on July 20.

The Command Module is the only portion of the spacecraft to return to Earth.

It was physically transferred to the Smithsonian in 1971 following a NASA-sponsored tour of American cities.

The Apollo CM Columbia has been designated a "Milestone of Flight" by the Museum.

Do not reproduce without permission from the Smithsonian Institution, National Air and Space Museum

Buzz AldrinMichael CollinsNeil A. Armstrong, 1930 - 2012

Transferred from the National Aeronautics and Space Administration

Primary Materials: Aluminum alloy, Stainless steel, Titanium

National Air and Space Museum Collection

The final leg of the Moon rock's journey to Earth was aboard the command module America, similar to the Apollo 11 command module, Columbia.

On each Apollo mission that landed humans on the Moon (11, 12, 14, 15, and 17), the Lunar module rendezvoused with a command module in lunar orbit.

Neil Armstrong, the first human to walk on the Moon, flew in Columbia as Commander of Apollo 11 and piloted the Museum's X-15.

### Model, Space Shuttle, North American Rockwell Final...

### Rocket Engine, Liquid Fuel, Apollo Lunar Module Descent...

### Space Shuttle Radar Topography Mission Canister, Antenna

### Satellite, Communications, Sirius FM-4

### Gemini Paraglider Research Vehicle 1-A with Wing

The Command Module "Columbia" went on a tour of the United States, visiting 49 state capitals, the District of Columbia, and Anchorage, Alaska. In 1971, it was transferred to the Smithsonian Institution.


Lower activity of CYP1A2 in South Asians appears to be due to cooking these vegetables in curries.

(meta data) TITLE: News | The University of Sydney

# The University of Sydney - The University of Sydney School of Pharmacy

You are here: University of Sydney / Sydney Pharmacy School / News & Events

## South Asians and Europeans react differently to common drugs

17 October 2011 Vidja Perera, NSW winner of the AusBiotech/GlaxoSmithKline Student Excellence Awards

Vidya Perera, a final year PhD student in theFaculty of Pharmacy, has found that people from South Asia could need lower doses of these medicines because they are likely to have lower levels of CYP1A2, an enzyme that metabolises drugs.

"Vegetables such as cabbages, cauliflower and broccoli are known to increase levels of CYP1A2, as was demonstrated in this study and previous studies in people of European background.

The lower levels of CYP1A2 in South Asians, however, appears to be due to the common practice of cooking these vegetables in curries using ingredients such as cumin and tumeric, ingredients known to inhibit the enzyme, overriding the effect of the vegetables," Mr Perera explained.

Mr Perera has just been declared the NSW winner of the AusBiotech/GlaxoSmithKline Student Excellence Awards as a result of his research.

"I started out looking for genetic differences between the two groups to account for the differences in CYP1A2 activity.

What was fascinating to discover is that genetic differences only accounted for 3 per cent of variability in CYP1A2 activity, while environment and lifestyle factors accounted for 35 percent of the differences," Mr Perera said.

A total of 332 people took part in the study - 166 South Asians and 166 Europeans.

CYP1A2 levels were measured by giving participants a caffeine tablet, and analysing CYP1A2 enzyme activity in saliva samples four hours later.

Demographic, dietary and lifestyle information was obtained using a questionnaire.

"Most drugs are approved in clinical trials conducted in Europe and North America using healthy, middle-aged European men," Mr Perera explained.

"This is the first study to look at CYP1A2 activity in South Asians.

Understanding the correct dose of a medicine is crucial to achieving beneficial results and avoiding adverse drug reactions."

Professor Andrew McLachlan, Associate Dean (Research) in the Faculty of Pharmacy and Mr Perera's PhD supervisor, commented on the significance of this research.

"The development and testing of medicines is a global enterprise.

The highest population growth is occurring in South Asia, yet we know relatively little about how to translate research findings between different populations of people."

"This research, for the first time, unpacks the complex interplay of factors that can affect how people breakdown and eliminate medicines from their body."

"Past research has attributed differences between people from different geographical regions to result from genetic differences.

This important research highlights how dietary and cultural factors can impact on pharmacological response."

AusBiotech 2011 is the annual conference of AusBiotech and the premier biotechnology and life sciences conference for Australia and the Asia-Pacific, attracting over 1400 delegates from across the world each year.

GlaxoSmithKline (GSK) is a global research-based pharmaceutical and healthcare company.

It collaborates with local researchers and doctors to discover new ways of treating and preventing disease.

Mr Perera is the recipient of the Peter Coates Postgraduate Scholarship in Ethnopharmacology, supported by GSK.

Authorised by: Dean, Faculty of Pharmacy.

Contacts | Sitemap | Jobs | Library | Disclaimer | Privacy Statement

Expression of CYP1A2 appears to be induced by various dietary constituents. Vegetables such as cabbages, cauliflower and broccoli are known to increase levels of CYP1A2.


The curries use ingredients such as cumin and turmeric.

(meta data) TITLE: News | The University of Sydney

# The University of Sydney - The University of Sydney School of Pharmacy

You are here: University of Sydney / Sydney Pharmacy School / News & Events

## South Asians and Europeans react differently to common drugs

17 October 2011 Vidja Perera, NSW winner of the AusBiotech/GlaxoSmithKline Student Excellence Awards

Vidya Perera, a final year PhD student in theFaculty of Pharmacy, has found that people from South Asia could need lower doses of these medicines because they are likely to have lower levels of CYP1A2, an enzyme that metabolises drugs.

"Vegetables such as cabbages, cauliflower and broccoli are known to increase levels of CYP1A2, as was demonstrated in this study and previous studies in people of European background.

The lower levels of CYP1A2 in South Asians, however, appears to be due to the common practice of cooking these vegetables in curries using ingredients such as cumin and tumeric, ingredients known to inhibit the enzyme, overriding the effect of the vegetables," Mr Perera explained.

Mr Perera has just been declared the NSW winner of the AusBiotech/GlaxoSmithKline Student Excellence Awards as a result of his research.

"I started out looking for genetic differences between the two groups to account for the differences in CYP1A2 activity.

What was fascinating to discover is that genetic differences only accounted for 3 per cent of variability in CYP1A2 activity, while environment and lifestyle factors accounted for 35 percent of the differences," Mr Perera said.

A total of 332 people took part in the study - 166 South Asians and 166 Europeans.

CYP1A2 levels were measured by giving participants a caffeine tablet, and analysing CYP1A2 enzyme activity in saliva samples four hours later.

Demographic, dietary and lifestyle information was obtained using a questionnaire.

"Most drugs are approved in clinical trials conducted in Europe and North America using healthy, middle-aged European men," Mr Perera explained.

"This is the first study to look at CYP1A2 activity in South Asians.

Understanding the correct dose of a medicine is crucial to achieving beneficial results and avoiding adverse drug reactions."

Professor Andrew McLachlan, Associate Dean (Research) in the Faculty of Pharmacy and Mr Perera's PhD supervisor, commented on the significance of this research.

"The development and testing of medicines is a global enterprise.

The highest population growth is occurring in South Asia, yet we know relatively little about how to translate research findings between different populations of people."

"This research, for the first time, unpacks the complex interplay of factors that can affect how people breakdown and eliminate medicines from their body."

"Past research has attributed differences between people from different geographical regions to result from genetic differences.

This important research highlights how dietary and cultural factors can impact on pharmacological response."

AusBiotech 2011 is the annual conference of AusBiotech and the premier biotechnology and life sciences conference for Australia and the Asia-Pacific, attracting over 1400 delegates from across the world each year.

GlaxoSmithKline (GSK) is a global research-based pharmaceutical and healthcare company.

It collaborates with local researchers and doctors to discover new ways of treating and preventing disease.

Mr Perera is the recipient of the Peter Coates Postgraduate Scholarship in Ethnopharmacology, supported by GSK.

Authorised by: Dean, Faculty of Pharmacy.

Contacts | Sitemap | Jobs | Library | Disclaimer | Privacy Statement

Expression of CYP1A2 appears to be induced by various dietary constituents. Vegetables such as cabbages, cauliflower and broccoli are known to increase levels of CYP1A2. Lower activity of CYP1A2 in South Asians appears to be due to cooking these vegetables in curries.


These ingredients are known to inhibit the enzyme.

(meta data) TITLE: News | The University of Sydney

# The University of Sydney - The University of Sydney School of Pharmacy

You are here: University of Sydney / Sydney Pharmacy School / News & Events

## South Asians and Europeans react differently to common drugs

17 October 2011 Vidja Perera, NSW winner of the AusBiotech/GlaxoSmithKline Student Excellence Awards

Vidya Perera, a final year PhD student in theFaculty of Pharmacy, has found that people from South Asia could need lower doses of these medicines because they are likely to have lower levels of CYP1A2, an enzyme that metabolises drugs.

"Vegetables such as cabbages, cauliflower and broccoli are known to increase levels of CYP1A2, as was demonstrated in this study and previous studies in people of European background.

The lower levels of CYP1A2 in South Asians, however, appears to be due to the common practice of cooking these vegetables in curries using ingredients such as cumin and tumeric, ingredients known to inhibit the enzyme, overriding the effect of the vegetables," Mr Perera explained.

Mr Perera has just been declared the NSW winner of the AusBiotech/GlaxoSmithKline Student Excellence Awards as a result of his research.

"I started out looking for genetic differences between the two groups to account for the differences in CYP1A2 activity.

What was fascinating to discover is that genetic differences only accounted for 3 per cent of variability in CYP1A2 activity, while environment and lifestyle factors accounted for 35 percent of the differences," Mr Perera said.

A total of 332 people took part in the study - 166 South Asians and 166 Europeans.

CYP1A2 levels were measured by giving participants a caffeine tablet, and analysing CYP1A2 enzyme activity in saliva samples four hours later.

Demographic, dietary and lifestyle information was obtained using a questionnaire.

"Most drugs are approved in clinical trials conducted in Europe and North America using healthy, middle-aged European men," Mr Perera explained.

"This is the first study to look at CYP1A2 activity in South Asians.

Understanding the correct dose of a medicine is crucial to achieving beneficial results and avoiding adverse drug reactions."

Professor Andrew McLachlan, Associate Dean (Research) in the Faculty of Pharmacy and Mr Perera's PhD supervisor, commented on the significance of this research.

"The development and testing of medicines is a global enterprise.

The highest population growth is occurring in South Asia, yet we know relatively little about how to translate research findings between different populations of people."

"This research, for the first time, unpacks the complex interplay of factors that can affect how people breakdown and eliminate medicines from their body."

"Past research has attributed differences between people from different geographical regions to result from genetic differences.

This important research highlights how dietary and cultural factors can impact on pharmacological response."

AusBiotech 2011 is the annual conference of AusBiotech and the premier biotechnology and life sciences conference for Australia and the Asia-Pacific, attracting over 1400 delegates from across the world each year.

GlaxoSmithKline (GSK) is a global research-based pharmaceutical and healthcare company.

It collaborates with local researchers and doctors to discover new ways of treating and preventing disease.

Mr Perera is the recipient of the Peter Coates Postgraduate Scholarship in Ethnopharmacology, supported by GSK.

Authorised by: Dean, Faculty of Pharmacy.

Contacts | Sitemap | Jobs | Library | Disclaimer | Privacy Statement

Expression of CYP1A2 appears to be induced by various dietary constituents. Vegetables such as cabbages, cauliflower and broccoli are known to increase levels of CYP1A2. Lower activity of CYP1A2 in South Asians appears to be due to cooking these vegetables in curries. The curries use ingredients such as cumin and turmeric.