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800
The biological processes underlying physiological hypofunction of the salivary glands is not yet well understood, although the involvement of ROS is suspected [1-4].
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background
801
nidulans, we made use of a simple but straightforward approach as it had been described recently (Ray et al., 2004).
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method
802
In contrast to our results, one study reported that high AI correlated with poor survival of MPM patients [31], but the overall prognostic significance of apoptosis in cancer remains unclear [33, 34].
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result
803
Moreover, these general network properties were demonstrated to have great impacts on the networkbased problems, such as traffic transport [12, 13, 14, 15, 16], epidemic spreading [17, 18, 19, 20, 21], network attacks [22, 23, 24, 25, 26, 27, 28], synchronization [29, 30] and control [31, 32, 33, 34, 35, 36], link prediction [37, 38, 39], etc.
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background
804
Oxidative damage of telomeres along with a general damage of DNA because of aged and thereby inefficient mitochondria could be an explanation (Chen et al., 1995), although contradictory results have been published on this matter (von Zglinicki et al., 2000; Britt-Compton et al., 2009).
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result
805
The STSS is thought to be mediated by the release of SPEs and other antigens, which function as superantigens (Proft et al., 2003; Marrack and Kappler, 1990; Talkington et al., 1993; Baxter and McChesney, 2000; Eriksson et al., 1999; Darenberg et al., 2004; Norrby-Teglund et al., 2005; Zurawski et al., 1998; Ekelund et al., 2005).
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background
806
The PPR and PRA-based approaches, together with the baseline, have been applied over graphs 1 and 2 (without and with SVO-inferred relationships, respectively).
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method
807
, 2008), high-order partial differential equations (Bai and Feng, 2007; Moraschi et al., 2010), diffusion tensor Enhancing quality in Diffusion Tensor Imaging with anisotropic anomalous diffusion filter
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background
808
Moreover, the key regulator of Fe homeostasis, Fur, is also directly regulated by PerR at the transcriptional level (Fuangthong et al., 2002).
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background
809
We generalize the model of Parke (1999), and it appears that fractional orders of integration at the seasonal frequencies may be caused by aggregation of seasonal duration processes.
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background
810
…cocaine seeking progressively increases over the first months of withdrawal from extended-access cocaine self-administration and remains elevated even 6 months after the last exposure (Neisewander et al., 2000; Grimm et al., 2001; Lu et al., 2004b; c; Sorge and Stewart, 2005; Pickens et al., 2011).
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background
811
The finding that BMI is closely related to TBF and PBF derived from DXA is compatible with several previous investigations in children over a wide age range and in adults (7, 13, 14, 16, 22, 24, 30, 32, 36).
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result
812
The results of the present dead weight noise testing indicate that the ‘CoP path velocity’ noise of the WBB (4.1–5.3 mm s 1) is considerable, which is in accordance with Pagnacco et al. (2011).
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result
813
However, our previous data on healthy paediatric patients (age 3 to 18 years) undergoing catheterisation for atrial septal defect closure resulted in a transfer function with the same peak at the fourth harmonic as demonstrated by Nichols and O’Rourke [8] suggesting the validity of this technique [9].
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method
814
…the growth of not only Bifidobacteria, but also of strains belonging to the Bacteroidetes and Actinobacteria phyla, while inhibiting Firmicutes strains (especially Clostridium) (Martinez et al., 2010), which is consistent with the presented results on the dietary fiber K1 and K2 preparations.
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result
815
(Notice that opponent spatiotemporal energy magnitude will be relatively large in response to a locally coherent motion [34].
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background
816
In addition, we recently demonstrated the important role of another 89-kDa periplasmic protein localized in the invasion tip during bacterial escape from the host digestive vacuole, migration through the host cytoplasm towards the target nucleus, and invasion into the macronucleus (Iwatani et al., 2005).
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background
817
Our results regarding cortisol are in line with several studies showing that sleep deprivation elevates cortisol levels.(34)
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result
818
Prior findings of a strong correlation between exposure to a pathogenic environment and CRP in the CLHNS sample provided impetus to further examine gene-by-pathogen interactions on CRP level [9, 10].
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background
819
Our proposed algorithm seeks to improve upon the performance of several existing algorithms, including ABS [47, 48, 18, 43], local principal component analysis (PCA) [5], local adaptive singular value cancellation (aSVC) [1] and non-local aSVC [1, Section 3.
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method
820
, 1998) and human (Straiker et al., 1999; Porcella et al. 2000) ciliary bodies of signi®cantly detectable levels of CB1 transcripts and proteins.
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background
821
These findings are in concordance with previously published studies suggesting a negative impact of Af sensitization in CF.15–17 Af sensitization likely facilitates CF-ABPA and multiple factors, including degree of fungal exposure, mucus viscosity, immune status, atopy and age may also have interdependent roles.12,32,39 Other factors, such as HLA-DR/HLA-DQ subtypes and the presence of single nucleotide polymorphisms 14 in the IL-4 binding site of IL-4 receptor alpha have also been described to associate with development of ABPA.40–42 Longitudinal studies are needed to confirm that Af sensitization routinely precedes ABPA.
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result
822
In this sense, accidentally encountered information is also always algorithmically framed and often personalised by for example previous searches and geographical location (e.g. Abel et al., 2011; Feuz et al., 2011; Hannak et al., 2013).
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method
823
The involvement of the clock in Pai-1 gene regulation has been described (Maemura et al., 2000; Minami et al., 2002; Schoenhard et al., 2003; Oishi et al., 2005a; Chong et al., 2006; Oishi et al., 2007), although the precise molecular mechanism on how the clock regulates the intrinsic daily…
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background
824
In contrast to most plant PPR proteins identified so far, which contain 12 PPR repeats on average (Lurin et al., 2004; Tourasse et al., 2013), PPR7 consists of only four PPR units, followed by a very short, positively charged conserved tail (Supplemental Figure 1).
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background
825
Second, we have previously shown that STAT3 expression was not changed by modulating RKIP expression in 293T cells [60] and third, because 293T cells have a higher transfection efficiency with the plasmids we were using, especially under the serum free conditions used in the experiments described below.
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background
826
Several authors (Anderson et al., 2009; Malmierca et al., 2009; Ulanovsky et al., 2004, 2003) use the normalized frequency difference: f norm, f2 − f1√ f1 f2 (A.1) where f1 and f2 have Hertz units, while others use the octave frequency separation (e.g., Von der Behrens et al., 2009).
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background
827
These polyphenols and other components have been described as having antioxidant (5), pro-oxidant (6), tumor inhibitory (7,8), antiapoptotic (9), antiangiogenesis (10,11), antiestrogenic (12,13), epigenetic (14), and other potentially chemopreventive properties (1,3,4,15,16).
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background
828
The methods of research are described in most detail in [1]; the methods of measurement and analysis of EEG coherence are described in [2]; brief information about their most essential elements is given below.
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method
829
In this study, we restrict perturbations of the kinematic environment to rotations of the visual feedback of the position of the end-effector, since this kind of transformation is well studied in both healthy human subjects and those with neurological disorders (Pine et al. 1996; Contreras-Vidal and Buch 2003).
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method
830
quantification of RAM in the biological fluids including liquid chromatography-tandem mass spectrometry (LC-MS/MS) (Gupta et al., 2011; Pilli et al., 2011; Patel et al., 2014), high performance
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method
831
Moreover, two distinct types of regulated secretion have been distinguished in neuronal and neuroendocrine cells (Kelly, 1993).
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background
832
Despite significant variation in the prevalence of unhealthy weights, results of this study are comparable to previous studies [14,16,49] showing the existence of the double burden of malnutrition in the seven African countries.
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result
833
In addition, more than three quarters of 97% OTUs in these proteobacterial classes contain SSU rRNA genes detected in PCR-based studies and appear in the SILVA database [12].
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background
834
These spatial variations in the sedimentary regime will drive coral species distributions depending on coral tolerances to sediments [16,17].
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background
835
zeamais, which could be an attractive alternative considering the great potential of the oil as insecticide and repellent, particularly because it is rich in monoterpenes [18].
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background
836
Binding of C2 domains (C2A, C2B, and C2AB) of SYT2 to phospholipids was measured according to previous descriptions (Fernandez et al., 2001; Fernandez-Chacon et al., 2002; Shin et al., 2003; Schapire et al., 2008).
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method
837
A discussion of particular channel estimation techniques is beyond the scope of this paper, therefore without loss of generality, we use the least-square (LS) channel estimator [14] in Sections IV and V due its widespread adoption in OFDM systems and low computational complexity.
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method
838
In addition, according to [6], instead of performing gradient descent based on Wh, we can compute the following formulation as:
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background
839
All katanin derivatives were PCR amplified from the human p60 (McNally and Thomas, 1998) or human p80 (Hartman et al., 1998) cDNAs previously described. p80 derivatives The WD40 domain of p80 (WD) consisted of amino acids 1-304, WDpro consisted of residues 1-484, pro-con80 consisted of residues…
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method
840
The effect of VEGF on glutamatergic transmission is still controversial, with evidence for both inhibition (McCloskey et al., 2005) and enhancement (Kim et al., 2008).
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background
841
Heavy metals contamination of Bohai Bay in the past few years have been investigated (Zhang et al. 2002; Hua et al. 2005; Wang et al. 2005; Wang and Li 2006; Wang and Wang 2007; Liu et al. 2007; Meng et al. 2008), however, no comparison was available to show the spatial and temporal distribution of heavy metals in the bay sediments in an 11-year duration.
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background
842
First, we prove that deciding whether a set of vertices of a graph G is a clique-transversal is Co-NP-Complete, a problem whose complexity is mentioned as open in [11].
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background
843
Evidence in the literature suggests that a non-CB1 receptor exists on excitatory terminals in the hippocampus (Hajos and Freund, 2002; Rouach and Nicoll, 2003), but this remains controversial (Hoffman et al., 2005; Kawamura et al., 2006; Takahashi and Castillo, 2006).
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background
844
This is troubling because hyperinsulinemia, a hallmark of insulin resistance, is considered a likely biological mechanism of increased risk for colon cancer and adenoma [1, 21].
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background
845
These measures provide important, but indirect, data on personal income, and may suffer from the “ecologic fallacy” of misclassifying income level on the basis of geographic economic factors, which can lead to substantial measurement error (22,23).
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background
846
Alternative splicing of exon 10 produces 2 tau protein isoforms, 3R (without exon 10) and 4R (with exon 10), and a healthy brain includes similar levels of 3R and 4R.(6) One study reported that the MAPT gene region that includes the 30-end of exon 10 and 50end of intron 10–11 is self-complementary and forms a hairpin (regulatory hairpin).
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background
847
4 tend to reach a ‘‘plateau’’ and do not converge at the same point, even though no spontaneous reactivation is detected (Estévez and Vilanova 2009).
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background
848
The increased ODC1 expression after fadrozole treatment may indicate an enhancement of the ODC/polyamine system and/or suggests a new pathway for E2 to regulate GABA production in addition to the known effects of E2 on glutamic acid decarboxylase in goldfish (46).
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method
849
Given their relatively low species diversity, biofilms growing within acid mine drainage (AMD) environments are a model system for the study of ecological processes in natural environments using ‘omic’ techniques (Denef et al., 2010a).
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background
850
The fact that others have shown that continued experience or exposure can modify when perceptual narrowing (or perceptual attenuation) occurs (Pascalis et al., 2005; Scott & Monesson, 2009), and the current results that perceptual discrimination is possible after narrowing has occurred, demonstrate…
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background
851
This result might explain why high IFP is associated with poor prognosis in human cancer (4, 21, 22).
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background
852
Climatic data Large scale climatic conditions have been shown to affect avian productivity in general (Nott et al. 2002).
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background
853
…construction site visit, site trainings, computer games and simulations, and problem-based learning, Though roleplaying is not a popular pedagogical approach adopted in construction education, it has major benefits and potentials for improving students‟ learning (Bhattacharjee & Ghosh, 2013).
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background
854
To get a rough approximation of the divergence time for the main phylogroups, we used both the higher and the lower sequence divergence rates proposed by Pinho et al. (2007) for the ND4–tRNALeu mitochondrial fragment (2.78% and 1.74% per million years, respectively).
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method
855
This is in agreement with a previous finding that wt CLN5 is stable in cells [12].
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result
856
Additionally, MeCP2 has been implicated not in inhibition but in the promotion of activity of some genes(Chahrour et al. 2008).
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method
857
Differences between the immune function of males and females have also been reported for birds (Romano et al., 2011), reptiles (Svensson et al., 2009) and fish (Hoeger et al., 2005).
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background
858
There is strong evidence that accumulation of Aβ peptide is responsible for age-related memory decline in these mice [5–7].
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background
859
DCS is preferable to External Storage (ES) at the base station, especially when there are many types of event to detect and report, and not all event types are queried often in a large network [56].
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background
860
6A) do not follow the characteristic dipper function found for superimposed masking (Legge and Foley, 1980; Foley, 1994).
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background
861
Given that normal hippocampal functioning is essential for both episodic AM and everyday memory (Vargha-Khadem et al., 1997; Isaacs et al., 2000), we also examined the effects of age and sex on everyday memory in order to determine whether the results would be similar to those observed in episodic…
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result
862
These results are aligned with the claims made by authors such as Kampenes et al. (2009), Jackson (2002), GroÃànniger et al. (2007), Petre (1995), as it was discussed in Sect.
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result
863
…as: P xið Þ ¼ e aþ Pn j¼1 bjxij 1þ e aþ Pn j¼1 bjxij : ð1Þ Here P(xi) is the probability of detection (0–1) of MODIS pixel i based on the linear combination of ASTER fire pixel summary statistics ( j=1,n), and α and βj are parameters derived from the data (Agresti, 1990; Morisette et al., 2005b).
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method
864
Nitrogen levels in the medium also influence the transcription of the ech42 endochitinase gene (Donzelli and Harman 2001).
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background
865
The electrode locations, acquired with a post-implantation CT were projected on the T1weighted individual anatomy scan (Hermes et al. 2010).
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method
866
3 To this end, the proposed method is compared with several recommendation methods including User-based CF (UCF), Item-based CF (ICF) [51], SlopeOne [52], SVD++ [53], TARS [12], SoRec [31], SoReg [54], TrustMF [22], SocialMF [28], TrustSVD [25], IPG [26], CETrust [21], and 2DGC [55].
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method
867
Protocol The study protocol followed the recommendations of the PRISMA statement and Cochrane Collaboration for systematic reviews and meta-analysis [12,13].
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method
868
Harpins are found to mediate HRbased PCD and produce elevated defense responses in plants (Lee et al. 2001a; Dong et al. 1999).
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background
869
The sequence of intermediates in the hR photocycle and their interconversions have been the subject of numerous studies (Va´ró et al., 1995a, b; Hazemoto et al., 1984; Zimányi and Lanyi, 1989a, b; Zima´nyi et al., 1989; Spencer and Dewey, 1990; Ames et al., 1992; Dioumaev and Braiman, 1997a).
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background
870
…and high levels of defecation are interpreted as indicators of high levels of emotionality (DeFries, Wilson, & McClearn, 1970; Flint et al., 1995; Gervais, 1976), although the validity of ambulation and defecation as indexes of emotionality has been questioned (Lister, 1990; Ramos & Mormède, 1998).
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background
871
Following prior work (Haghighi et al., 2008; Prochasson and Fung, 2011; Vulić and Moens, 2013b), we retain only nouns that occur at least 5 times in the corpus.
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method
872
5 nM and individuals need to ingest at least 25–50 μg of vitamin D per day to sustain a blood level of > 75 nM 25(OH) vitamin D [22, 23].
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background
873
The Caribbean sample includes sequences from Panama that were previously obtained by McCartney and Lessios (2004), with GenBank accession numbers AY451242–AY451275.
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background
874
The LAA orifice area was then calculated by using the equation [19]: LAA orifice area = π x (Dmax/2) x (Dmin/2).
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method
875
Discussion In the past five years, several studies have aimed to evaluate the impact of PTGS2 SNPs on the risk of developing different types of cancer [10,15,16,21-46].
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background
876
Fluoroscopy-guided anterior scalene (ASM) or pectoalis minor (PM) muscle blocks, or both, with local aneshetic were frequently used to help reinforce the clinical iagnosis of NTOS and to provide additional insight into he likely responsiveness to treatment.(7,11) All patients not reviously treated for NTOS and those for whom previous hysical therapy did not appear to have been suitably tareted toward NTOS, underwent a 4- to 6-week course of TOS-specific physical therapy overseen by a therapist ith experience and expertise in the management of TOS.
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method
877
It is estimated that the abuse and misuse of prescription opioids are responsible for somewhere between $53 to $72 billion in cumulative costs annually.(33,34) These fig-
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background
878
that can destroy tumor cells but are instead induced to suppress anti-tumor immune responses by releasing elevated levels of the immune suppressive products, nitric oxide, IL10 and TGF- , and down-regulating levels of the immune stimulatory product IL-12 [10, 17, 14, 20].
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background
879
…either undergoing pain or suffering emotionally, localized a core network including anterior insula (AI), inferior frontal gyrus (IFG), and anterior midcingulate cortex (aMCC) (Singer et al. 2004; Jackson et al. 2006; Singer 2006; Decety and Moriguchi 2007; Fan et al. 2011; Lamm et al. 2011).
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background
880
The differential magnitude of effect in large versus small studies (Ioannidis et al. 2003; Zintzaras et al. 2005) for the allele contrast was tested using the Egger regression test for funnel plot asymmetry (Egger et al. 1997) and the Begg-Mazumdar test, which is based on Kendall’s tau (Begg and…
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method
881
Even, the GU toxicity in our study are high, the observed rate averaged those described in former reports [1,4,5,7,10,11,25].
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result
882
…of these findings, the difference in thigmotaxis between the selectively bred HOFT and LOFT mice seemed to be a stable and robust feature of these animals, suggesting that the two lines differed with regard to trait anxiety rather than to state anxiety (see Belzung & Griebel, 2001; Lister, 1990).
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background
883
Division of Arabidopsis thaliana Proteins into Families using PFAM Each probeset in the Affymetrix ATH1 microarray platform was mapped using BLAST (Altschul et al., 1990) to the Table 3.
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method
884
The computational system arising from the ad-hoc computation network point of view has been modeled by combining the notion of distributed data streams [5] with classic distributed approaches to solve problems on particular topologies [6] as the SSSF model [2].
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method
885
Matthews et al. (2002) concluded that 3–4 days monitoring were required to correctly measure moderate-to-vigorous physical activity (MVPA), and that 7 days were needed to reliably estimate physical inactivity [5].
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background
886
Force feedback (FFB) has been shown to increase the usability and to decrease the cognitive workload during the surgery, as reflected in faster learning curves (Narazaki et al. 2006; Okamura 2009).
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background
887
Trait data collection We used 10 plant functional traits related to growth, survival, and the response to environmental change (Pérez-Harguindeguy et al. 2013), including leaf area (LA; mm2), specific leaf area (SLA; mm2 g 1), chlorophyll content (measured by the SPAD device unit [see below]),…
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method
888
Infection Control Measures/Investigation of Implicated Re-useable Medical Device: After the first site visit on May 31, 2006, ACDC issued interim recommendations including adding antibiotic coverage from gram-negative organisms for cardiac surgery patients, collecting surveillance cultures (sputum) on all intubated CVICU patients, collecting environmental cultures, and culturing the TEE equipment and removing it from use.
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method
889
Bifidobacteria is the third most common genus in the human intestine, constituting about 3% of the adult fecal flora and more than 75% of the infant fecal flora (Langendijk et al., 1995; Franks et al., 1998; Harmsen et al., 2000).
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background
890
Exercise has an important role not only in promoting general health but also in the prevention and treatment of various kinds of ailments, such as mood disorders (Agras, 1995) and constitutional hypotension (Duschek and Schandry, 2007).
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background
891
Note that Drieghe et al. (2008) have proposed that parafoveal-on-foveal effects (i.e., an effect of the word to the right of fixation that appears in the eye movement record before the eyes have actually left the fixated word) may be likely to arise in cases in which the saccadic targeting system…
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background
892
Starting from the reference C-based implementation provided in the CORTEXSUITE, a recently-released suite of benchmarks designed to challenge current hardware systems [26], we completed a design specification in synthesizable SystemC that is parametric with respect to the PLM size.
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method
893
The level of expression of amyloid- protein precursor investigated gene did not coincide with the earlier data concerning staining of different parts of amyloidprotein precursor in the rat cortex [17, 21].
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result
894
This transition was introduced first by Prince and Elder (2007) and it simplifies formulas for parameter update on Mstep of EM algorithm.
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method
895
Experimental evidence and clinical observations support the concept that these molecules participate in the pathogenesis of organ injury and that their blood levels correlate with severity of illness and outcome (5, 6).
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background
896
The frame rate was set between 60 and 90 frames per second.(7) Echocardiograms were digitally stored and later analysed off-line using acoustic-tracking software (Echo-Pac version 7.
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method
897
…side-effects are found with currently available hypnotics, it will be of interest to determine whether newer genetic methods for enhancing sleep in rodents can reverse/attenuate or slow-down Alzheimer's pathology in rodent models (Jego et al., 2013; Konadhode et al., 2013; Anaclet et al., 2014).
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background
898
Indeed, strong correlations between inhibitions at different ISIs have been reported previously (Roshan et al. 2003) which would be consistent with this idea.
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background
899
Although previous reports suggest that ISC differentiation is compromised by constant signals through CD40 (41, 42), in this study we demonstrate that activation through CD40 alone drives B cell differentiation, evidenced by moderate levels of Ig secretion.
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result