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ffpf0222 | 0 | {"lines_data": [{"Word": "From:", "Confidence": 0.997, "X1": 0.11705, "Y1": 0.0702, "X2": 0.17197, "Y2": 0.07, "X3": 0.17052, "Y3": 0.0828, "X4": 0.11705, "Y4": 0.0828, "page": 0}, {"Word": "Lauster, Steffen [LAUSTER_STEFFEN@bah.com]", "Confidence": 0.955, "X1": 0.23988, "Y1": 0.0692, "X2": 0.63728, "Y2": 0.069, "X3": 0.63728, "Y3": 0.0848, "X4": 0.23988, "Y4": 0.0848, "page": 0}, {"Word": "Sent:", "Confidence": 0.995, "X1": 0.1185, "Y1": 0.0892, "X2": 0.16618, "Y2": 0.089, "X3": 0.16618, "Y3": 0.1018, "X4": 0.11705, "Y4": 0.1018, "page": 0}, {"Word": "Wednesday, January 31, 2007 6:43:48 PM", "Confidence": 0.978, "X1": 0.23988, "Y1": 0.0882, "X2": 0.57803, "Y2": 0.088, "X3": 0.57803, "Y3": 0.1038, "X4": 0.23988, "Y4": 0.1038, "page": 0}, {"Word": "To:", "Confidence": 0.958, "X1": 0.11994, "Y1": 0.1082, "X2": 0.15173, "Y2": 0.108, "X3": 0.15173, "Y3": 0.1198, "X4": 0.11994, "Y4": 0.1188, "page": 0}, {"Word": "Delen, Daan", "Confidence": 0.991, "X1": 0.23844, "Y1": 0.1082, "X2": 0.34249, "Y2": 0.108, "X3": 0.34249, "Y3": 0.1208, "X4": 0.23844, "Y4": 0.1218, "page": 0}, {"Word": "Cc:", "Confidence": 0.814, "X1": 0.11705, "Y1": 0.1272, "X2": 0.1474, "Y2": 0.127, "X3": 0.14595, "Y3": 0.1388, "X4": 0.11705, "Y4": 0.1388, "page": 0}, {"Word": "Hicks, Susan R .: Moeller, Leslic: Bahadur, Nikhil", "Confidence": 0.89575, "X1": 0.23988, "Y1": 0.1252, "X2": 0.62283, "Y2": 0.125, "X3": 0.62283, "Y3": 0.1398, "X4": 0.23988, "Y4": 0.1398, "page": 0}, {"Word": "Subject:", "Confidence": 0.994, "X1": 0.11705, "Y1": 0.1452, "X2": 0.19364, "Y2": 0.145, "X3": 0.19364, "Y3": 0.1588, "X4": 0.11705, "Y4": 0.1588, "page": 0}, {"Word": "Portfolio Risk Ranking for Board Discussion next week", "Confidence": 0.99212, "X1": 0.23988, "Y1": 0.1442, "X2": 0.66763, "Y2": 0.144, "X3": 0.66763, "Y3": 0.1598, "X4": 0.23988, "Y4": 0.1598, "page": 0}, {"Word": "Attachments: 07-01-31 Overview Slides for Board Deck Steffen.ppt", "Confidence": 0.988, "X1": 0.11705, "Y1": 0.1632, "X2": 0.65607, "Y2": 0.163, "X3": 0.65607, "Y3": 0.1788, "X4": 0.11705, "Y4": 0.1778, "page": 0}, {"Word": "Dan:", "Confidence": 0.994, "X1": 0.1185, "Y1": 0.1972, "X2": 0.15751, "Y2": 0.197, "X3": 0.15607, "Y3": 0.2088, "X4": 0.1185, "Y4": 0.2088, "page": 0}, {"Word": "Thanks again for your great comments yesterday during the Steering Committee meeting. You", "Confidence": 0.96369, "X1": 0.1185, "Y1": 0.2112, "X2": 0.85838, "Y2": 0.211, "X3": 0.85838, "Y3": 0.2268, "X4": 0.1185, "Y4": 0.2268, "page": 0}, {"Word": "really drove the thinking along. I wanted to get back to you on a number of your suggestions:", "Confidence": 0.99172, "X1": 0.1185, "Y1": 0.2272, "X2": 0.83815, "Y2": 0.227, "X3": 0.83815, "Y3": 0.2418, "X4": 0.1185, "Y4": 0.2418, "page": 0}, {"Word": "1.", "Confidence": 0.998, "X1": 0.11994, "Y1": 0.2562, "X2": 0.13873, "Y2": 0.256, "X3": 0.14017, "Y3": 0.2708, "X4": 0.11994, "Y4": 0.2708, "page": 0}, {"Word": "Portfolio Mapping: We have taken another shot at the portfolio summary pages which", "Confidence": 0.99108, "X1": 0.19798, "Y1": 0.2562, "X2": 0.86561, "Y2": 0.256, "X3": 0.86561, "Y3": 0.2718, "X4": 0.19798, "Y4": 0.2708, "page": 0}, {"Word": "we also plan to use to conclude the discussion with the Board. 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That would be great!", "Confidence": 0.97789, "X1": 0.11561, "Y1": 0.3022, "X2": 0.57659, "Y2": 0.302, "X3": 0.57659, "Y3": 0.3158, "X4": 0.11561, "Y4": 0.3158, "page": 0}, {"Word": "2.", "Confidence": 0.994, "X1": 0.1185, "Y1": 0.3162, "X2": 0.15462, "Y2": 0.316, "X3": 0.15462, "Y3": 0.3328, "X4": 0.1185, "Y4": 0.3308, "page": 0}, {"Word": "You raised some very good points around the development of the super premium", "Confidence": 0.98615, "X1": 0.1922, "Y1": 0.3162, "X2": 0.83237, "Y2": 0.316, "X3": 0.83237, "Y3": 0.3308, "X4": 0.1922, "Y4": 0.3308, "page": 0}, {"Word": "category and what the implications for our strategy could be (e.g. how many brands ?, category", "Confidence": 0.98675, "X1": 0.11705, "Y1": 0.3312, "X2": 0.85694, "Y2": 0.331, "X3": 0.85694, "Y3": 0.3458, "X4": 0.11705, "Y4": 0.3458, "page": 0}, {"Word": "vs. brand focus, organizational implications). We would like to get back to you on this both to", "Confidence": 0.98794, "X1": 0.1185, "Y1": 0.3462, "X2": 0.84104, "Y2": 0.346, "X3": 0.84104, "Y3": 0.3598, "X4": 0.1185, "Y4": 0.3608, "page": 0}, {"Word": "provide you with our perspective and also discuss your concerns/suggestions in more detail. I will", "Confidence": 0.93073, "X1": 0.11705, "Y1": 0.3612, "X2": 0.87861, "Y2": 0.361, "X3": 0.88006, "Y3": 0.3748, "X4": 0.11705, "Y4": 0.3758, "page": 0}, {"Word": "reach out to Susan if we can find some time on your schedule over the next weeks.", "Confidence": 0.98794, "X1": 0.11994, "Y1": 0.3762, "X2": 0.76445, "Y2": 0.376, "X3": 0.76445, "Y3": 0.3908, "X4": 0.11994, "Y4": 0.3908, "page": 0}, {"Word": "3.", "Confidence": 0.997, "X1": 0.11994, "Y1": 0.3912, "X2": 0.13439, "Y2": 0.391, "X3": 0.13439, "Y3": 0.4048, "X4": 0.11994, "Y4": 0.4048, "page": 0}, {"Word": "Intangible strategic benefits: As you correctly stated, we have so far mainly focused on", "Confidence": 0.98364, "X1": 0.1922, "Y1": 0.3912, "X2": 0.87428, "Y2": 0.391, "X3": 0.87428, "Y3": 0.4058, "X4": 0.1922, "Y4": 0.4058, "page": 0}, {"Word": "the more tangible aspects of the individual strategies (Right to Win, Financials) but have not fully", "Confidence": 0.98162, "X1": 0.11705, "Y1": 0.4062, "X2": 0.86994, "Y2": 0.406, "X3": 0.86994, "Y3": 0.4208, "X4": 0.11705, "Y4": 0.4198, "page": 0}, {"Word": "articulated higher level portfolio benefits (e.g. growth aligned with iPrime creating more chances", "Confidence": 0.97677, "X1": 0.11705, "Y1": 0.4212, "X2": 0.86416, "Y2": 0.421, "X3": 0.86416, "Y3": 0.4358, "X4": 0.11705, "Y4": 0.4348, "page": 0}, {"Word": "of societal permission to operate in a less constrained environment, the halo effect of a Super", "Confidence": 0.98831, "X1": 0.1185, "Y1": 0.4362, "X2": 0.84827, "Y2": 0.436, "X3": 0.84827, "Y3": 0.4498, "X4": 0.1185, "Y4": 0.4498, "page": 0}, {"Word": "Premium category, the benefits of more international growth ,.... ). We will work on this over the", "Confidence": 0.92135, "X1": 0.1185, "Y1": 0.4512, "X2": 0.84971, "Y2": 0.451, "X3": 0.84971, "Y3": 0.4648, "X4": 0.11705, "Y4": 0.4648, "page": 0}, {"Word": "next weeks and explicitly discuss this as we make portfolio trade-offs in our next Steering", "Confidence": 0.98733, "X1": 0.11705, "Y1": 0.4662, "X2": 0.81214, "Y2": 0.466, "X3": 0.81214, "Y3": 0.4798, "X4": 0.11705, "Y4": 0.4798, "page": 0}, {"Word": "Committee meeting. I will pass this by you once we have a good working draft.", "Confidence": 0.98793, "X1": 0.1185, "Y1": 0.4802, "X2": 0.72832, "Y2": 0.48, "X3": 0.72832, "Y3": 0.4948, "X4": 0.11705, "Y4": 0.4948, "page": 0}, {"Word": "I will reach out to you tomorrow to see if we can get your feedback on the portfolio pages as we", "Confidence": 0.98029, "X1": 0.1185, "Y1": 0.5102, "X2": 0.86416, "Y2": 0.51, "X3": 0.86416, "Y3": 0.5258, "X4": 0.1185, "Y4": 0.5248, "page": 0}, {"Word": "are finalizing the Board deck.", "Confidence": 0.9954, "X1": 0.11705, "Y1": 0.5252, "X2": 0.34682, "Y2": 0.525, "X3": 0.34682, "Y3": 0.5398, "X4": 0.11705, "Y4": 0.5408, "page": 0}, {"Word": "Best", "Confidence": 0.989, "X1": 0.11705, "Y1": 0.5572, "X2": 0.15607, "Y2": 0.557, "X3": 0.15462, "Y3": 0.5688, "X4": 0.11705, "Y4": 0.5688, "page": 0}, {"Word": "Steffen", "Confidence": 0.997, "X1": 0.1185, "Y1": 0.5702, "X2": 0.17775, "Y2": 0.57, "X3": 0.17775, "Y3": 0.5838, "X4": 0.11705, "Y4": 0.5828, "page": 0}], 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These striking dif.", "Confidence": 0.86617, "X1": 0.50404, "Y1": 0.4782, "X2": 0.92722, "Y2": 0.478, "X3": 0.92857, "Y3": 0.4908, "X4": 0.50404, "Y4": 0.4918, "page": 0}, {"Word": "mg/ml. As pH 8. The concentration of nicotine as free baas", "Confidence": 0.76109, "X1": 0.06334, "Y1": 0.4902, "X2": 0.48922, "Y2": 0.49, "X3": 0.48922, "Y3": 0.5028, "X4": 0.06334, "Y4": 0.5038, "page": 0}, {"Word": "ferenons are consistent with the differences in the pharma-", "Confidence": 0.76967, "X1": 0.5027, "Y1": 0.4912, "X2": 0.92318, "Y2": 0.491, "X3": 0.92318, "Y3": 0.5028, "X4": 0.5027, "Y4": 0.5028, "page": 0}, {"Word": "wad 0-18 mg/ml. at PH 7 and 0-13 mg/ml. st >H 8, showing", "Confidence": 0.72377, "X1": 0.06334, "Y1": 0.5022, "X2": 0.48922, "Y2": 0.502, "X3": 0.48922, "Y3": 0.5148, "X4": 0.06334, "Y4": 0.5158, "page": 0}, {"Word": "cological effects of the relatively large amounts of cigarette", "Confidence": 0.74322, "X1": 0.5, "Y1": 0.5032, "X2": 0.92453, "Y2": 0.503, "X3": 0.92453, "Y3": 0.5158, "X4": 0.5, "Y4": 0.5148, "page": 0}, {"Word": "that the pharmacological response is clearly dependent", "Confidence": 0.72771, "X1": 0.06334, "Y1": 0.5142, "X2": 0.48518, "Y2": 0.514, "X3": 0.48518, "Y3": 0.5278, "X4": 0.06334, "Y4": 0.5278, "page": 0}, {"Word": "wod cigar smoke used in the present experimenta.", "Confidence": 0.489, "X1": 0.50404, "Y1": 0.5152, "X2": 0.86792, "Y2": 0.515, "X3": 0.86792, "Y3": 0.5268, "X4": 0.50404, "Y4": 0.5268, "page": 0}, {"Word": "on the amount of nicotine in the mouth ss free base.", "Confidence": 0.82009, "X1": 0.06739, "Y1": 0.5262, "X2": 0.48518, "Y2": 0.526, "X3": 0.48518, "Y3": 0.5398, "X4": 0.06739, "Y4": 0.5398, "page": 0}, {"Word": "We have recently shown that twenty intravenous injec-", "Confidence": 0.68075, "X1": 0.51617, "Y1": 0.5262, "X2": 0.92453, "Y2": 0.526, "X3": 0.92453, "Y3": 0.5398, "X4": 0.51617, "Y4": 0.5398, "page": 0}, {"Word": "Fig. 2 shows the mean carotid blood levels of nicotine", "Confidence": 0.7258, "X1": 0.07682, "Y1": 0.5382, "X2": 0.48787, "Y2": 0.538, "X3": 0.48787, "Y3": 0.5508, "X4": 0.07682, "Y4": 0.5518, "page": 0}, {"Word": "tions of nicotine (4 g/kg). given rapidly at minute", "Confidence": 0.78367, "X1": 0.50539, "Y1": 0.5382, "X2": 0.92588, "Y2": 0.538, "X3": 0.92588, "Y3": 0.5518, "X4": 0.50539, "Y4": 0.5518, "page": 0}, {"Word": "in ng/ml. after the introduction into the mouth for 10 min", "Confidence": 0.91345, "X1": 0.06604, "Y1": 0.5502, "X2": 0.48652, "Y2": 0.55, "X3": 0.48652, "Y3": 0.5628, "X4": 0.06604, "Y4": 0.5648, "page": 0}, {"Word": "intervals for 20 min. cansod during the first 2-5 min &", "Confidence": 0.72482, "X1": 0.5027, "Y1": 0.5502, "X2": 0.92588, "Y2": 0.55, "X3": 0.92588, "Y3": 0.5628, "X4": 0.5027, "Y4": 0.5638, "page": 0}, {"Word": "of solutions of nipotino at aH 6, 7 and 8 each of which can-", "Confidence": 0.73171, "X1": 0.06334, "Y1": 0.5622, "X2": 0.48518, "Y2": 0.562, "X3": 0.48518, "Y3": 0.5748, "X4": 0.06334, "Y4": 0.5768, "page": 0}, {"Word": "15 ag/ml./min rise in the concentration of nicotine in", "Confidence": 0.77944, "X1": 0.50404, "Y1": 0.5622, "X2": 0.92588, "Y2": 0.562, "X3": 0.92588, "Y3": 0.5758, "X4": 0.50404, "Y4": 0.5768, "page": 0}, {"Word": "tained 0-8 mg/ml. (1.3 pCi/ml.) (2'.\"C).nicotine. Nicotina", "Confidence": 0.67629, "X1": 0.06469, "Y1": 0.5742, "X2": 0.48652, "Y2": 0.574, "X3": 0.48652, "Y3": 0.5868, "X4": 0.06469, "Y4": 0.5888, "page": 0}, {"Word": "carotid blood and a peak concentration of 100 ng/ml. at", "Confidence": 0.9018, "X1": 0.5027, "Y1": 0.5742, "X2": 0.92722, "Y2": 0.574, "X3": 0.92722, "Y3": 0.5868, "X4": 0.5027, "Y4": 0.5888, "page": 0}, {"Word": "concentrations in blood (? mi, sample ) were determined", "Confidence": 0.62689, "X1": 0.06469, "Y1": 0.5872, "X2": 0.48518, "Y2": 0.587, "X3": 0.48518, "Y3": 0.5998, "X4": 0.06469, "Y4": 0.6008, "page": 0}, {"Word": "20 min. This is probably the sort of blood concentration", "Confidence": 0.7865, "X1": 0.5027, "Y1": 0.5872, "X2": 0.92453, "Y2": 0.587, "X3": 0.92453, "Y3": 0.5998, "X4": 0.5027, "Y4": 0.5998, "page": 0}, {"Word": "by the method described by Tumer\". The graphs were", "Confidence": 0.83522, "X1": 0.06334, "Y1": 0.5992, "X2": 0.48518, "Y2": 0.599, "X3": 0.48518, "Y3": 0.6118, "X4": 0.06334, "Y4": 0.6128, "page": 0}, {"Word": "pattern that must be achieved to elicit & stimulant ree-", "Confidence": 0.6506, "X1": 0.5027, "Y1": 0.5992, "X2": 0.92588, "Y2": 0.599, "X3": 0.92588, "Y3": 0.6108, "X4": 0.5027, "Y4": 0.6118, "page": 0}, {"Word": "drawn from data obtained in nins experiments. Whether", "Confidence": 0.69687, "X1": 0.06469, "Y1": 0.6102, "X2": 0.48652, "Y2": 0.61, "X3": 0.48652, "Y3": 0.6228, "X4": 0.06469, "Y4": 0.6248, "page": 0}, {"Word": "ponce. The data illustrated in Fig. 2 show that such", "Confidence": 0.8822, "X1": 0.50135, "Y1": 0.6112, "X2": 0.92318, "Y2": 0.611, "X3": 0.92318, "Y3": 0.6238, "X4": 0.50135, "Y4": 0.6248, "page": 0}, {"Word": "nicotine exerts a pharmacological response depends on", "Confidence": 0.63257, "X1": 0.06199, "Y1": 0.6222, "X2": 0.48518, "Y2": 0.622, "X3": 0.48518, "Y3": 0.6348, "X4": 0.06199, "Y4": 0.6378, "page": 0}, {"Word": "blood levels are achieved ( but only just st pli 6) when", "Confidence": 0.75483, "X1": 0.50539, "Y1": 0.6212, "X2": 0.92722, "Y2": 0.621, "X3": 0.92722, "Y3": 0.6348, "X4": 0.50539, "Y4": 0.6368, "page": 0}, {"Word": "the rate at which it appears in the blood and on the peak", "Confidence": 0.90846, "X1": 0.06065, "Y1": 0.6352, "X2": 0.48922, "Y2": 0.635, "X3": 0.48922, "Y3": 0.6468, "X4": 0.06065, "Y4": 0.6488, "page": 0}, {"Word": "nicotine is present in the mouth ocatinuously for 10 min", "Confidence": 0.8037, "X1": 0.5027, "Y1": 0.6332, "X2": 0.92453, "Y2": 0.633, "X3": 0.92453, "Y3": 0.6468, "X4": 0.5027, "Y4": 0.6488, "page": 0}, {"Word": "concentration attained\". The peak concentration of", "Confidence": 0.61217, "X1": 0.06334, "Y1": 0.6462, "X2": 0.48518, "Y2": 0.646, "X3": 0.48518, "Y3": 0.6588, "X4": 0.06334, "Y4": 0.6608, "page": 0}, {"Word": "At the relatively high concentration of 0-8 mg/ml. During", "Confidence": 0.804, "X1": 0.5027, "Y1": 0.6472, "X2": 0.92722, "Y2": 0.647, "X3": 0.92722, "Y3": 0.6608, "X4": 0.5027, "Y4": 0.6608, "page": 0}, {"Word": "nicotine at plf 8 was approximately 2-5 times that at", "Confidence": 0.6232, "X1": 0.06199, "Y1": 0.6582, "X2": 0.48652, "Y2": 0.658, "X3": 0.48652, "Y3": 0.6708, "X4": 0.06199, "Y4": 0.6728, "page": 0}, {"Word": "the emaking of a cigarette or cigar, however, amoke is", "Confidence": 0.8836, "X1": 0.5027, "Y1": 0.6582, "X2": 0.92588, "Y2": 0.658, "X3": 0.92588, "Y3": 0.6718, "X4": 0.5027, "Y4": 0.6718, "page": 0}, {"Word": "PH 7 and four times that at pH &. The rate at which the", "Confidence": 0.83914, "X1": 0.06199, "Y1": 0.6712, "X2": 0.48787, "Y2": 0.671, "X3": 0.48922, "Y3": 0.6838, "X4": 0.06199, "Y4": 0.6858, "page": 0}, {"Word": "taken into the mouth intermittently and held there for", "Confidence": 0.88944, "X1": 0.50135, "Y1": 0.6702, "X2": 0.92453, "Y2": 0.67, "X3": 0.92453, "Y3": 0.6828, "X4": 0.50135, "Y4": 0.6848, "page": 0}, {"Word": "concentration of nicotine in the blood increased in the", "Confidence": 0.82444, "X1": 0.06199, "Y1": 0.6822, "X2": 0.48922, "Y2": 0.682, "X3": 0.48922, "Y3": 0.6948, "X4": 0.06199, "Y4": 0.6988, "page": 0}, {"Word": "only a few seconds. The concentration of nicotine bathing", "Confidence": 0.60811, "X1": 0.50135, "Y1": 0.6822, "X2": 0.92588, "Y2": 0.682, "X3": 0.92588, "Y3": 0.6948, "X4": 0.50135, "Y4": 0.6968, "page": 0}, {"Word": "first 2.5 min at pH 8 was about 3.5 times the rate at", "Confidence": 0.64054, "X1": 0.06469, "Y1": 0.6952, "X2": 0.48652, "Y2": 0.695, "X3": 0.48787, "Y3": 0.7068, "X4": 0.06469, "Y4": 0.7088, "page": 0}, {"Word": "the mucous membranes of the mouth is not known, but", "Confidence": 0.7834, "X1": 0.50135, "Y1": 0.6942, "X2": 0.92588, "Y2": 0.694, "X3": 0.92588, "Y3": 0.7068, "X4": 0.50135, "Y4": 0.7088, "page": 0}, {"Word": "clearly the conditions are less favourable for absorption", "Confidence": 0.68988, "X1": 0.5027, "Y1": 0.7062, "X2": 0.92453, "Y2": 0.706, "X3": 0.92453, "Y3": 0.7188, "X4": 0.5027, "Y4": 0.7208, "page": 0}, {"Word": "than in the experiments of Fig. 2. The present evidence", "Confidence": 0.8141, "X1": 0.5027, "Y1": 0.7192, "X2": 0.92453, "Y2": 0.719, "X3": 0.92453, "Y3": 0.7318, "X4": 0.5027, "Y4": 0.7328, "page": 0}, {"Word": "indicates that cigarette smokera who do not inhale may", "Confidence": 0.67656, "X1": 0.50404, "Y1": 0.7312, "X2": 0.92453, "Y2": 0.731, "X3": 0.92453, "Y3": 0.7438, "X4": 0.50404, "Y4": 0.7448, "page": 0}, {"Word": "not obtain a \"stimulant\" dose of nicotine from relatively", "Confidence": 0.70011, "X1": 0.5027, "Y1": 0.7432, "X2": 0.92453, "Y2": 0.743, "X3": 0.92453, "Y3": 0.7548, "X4": 0.5027, "Y4": 0.7568, "page": 0}, {"Word": "acidio cigarette smoke. It may, however, bo possible for", "Confidence": 0.68289, "X1": 0.5027, "Y1": 0.7542, "X2": 0.92453, "Y2": 0.754, "X3": 0.92453, "Y3": 0.7678, "X4": 0.5027, "Y4": 0.7688, "page": 0}, {"Word": ".00", "Confidence": 0.495, "X1": 0.07951, "Y1": 0.7682, "X2": 0.10108, "Y2": 0.768, "X3": 0.09838, "Y3": 0.7768, "X4": 0.07817, "Y4": 0.7768, "page": 0}, {"Word": "a cigar smoker to obtain such a doce without inhaling.", "Confidence": 0.9093, "X1": 0.50809, "Y1": 0.7662, "X2": 0.90701, "Y2": 0.766, "X3": 0.90701, "Y3": 0.7788, "X4": 0.50809, "Y4": 0.7808, "page": 0}, {"Word": "We thank Mir C. A. Grant for the nicotine analyses and", "Confidence": 0.83109, "X1": 0.51617, "Y1": 0.7772, "X2": 0.92318, "Y2": 0.777, "X3": 0.92318, "Y3": 0.7928, "X4": 0.51617, "Y4": 0.7918, "page": 0}, {"Word": "PH determinations of cigarette and cigar smoke, Dr H.", "Confidence": 0.85289, "X1": 0.50135, "Y1": 0.7892, "X2": 0.92453, "Y2": 0.789, "X3": 0.92453, "Y3": 0.8028, "X4": 0.50135, "Y4": 0.8048, "page": 0}, {"Word": "Roderick for providing the (-).(2'.\"(C) nicotine hydrogen", "Confidence": 0.64971, "X1": 0.5027, "Y1": 0.8012, "X2": 0.92453, "Y2": 0.801, "X3": 0.92453, "Y3": 0.8148, "X4": 0.5027, "Y4": 0.8158, "page": 0}, {"Word": "200", "Confidence": 0.761, "X1": 0.07817, "Y1": 0.8142, "X2": 0.10108, "Y2": 0.814, "X3": 0.10108, "Y3": 0.8248, "X4": 0.07951, "Y4": 0.8248, "page": 0}, {"Word": "tartrate, Mr C. M. Belleza and Mrs D. Kendall for technien", "Confidence": 0.74664, "X1": 0.5027, "Y1": 0.8122, "X2": 0.92453, "Y2": 0.812, "X3": 0.92453, "Y3": 0.8258, "X4": 0.5027, "Y4": 0.8288, "page": 0}, {"Word": "smistance and Mr B. Emmett for preparing the figures.", "Confidence": 0.75689, "X1": 0.50135, "Y1": 0.8262, "X2": 0.90701, "Y2": 0.826, "X3": 0.90701, "Y3": 0.8398, "X4": 0.50135, "Y4": 0.8398, "page": 0}, {"Word": "Armitage, A. F ., grid. J. Pharmsol .. 36. 515 01645).", "Confidence": 0.31909, "X1": 0.50943, "Y1": 0.8702, "X2": 0.80863, "Y2": 0.87, "X3": 0.80863, "Y3": 0.8808, "X4": 0.50943, "Y4": 0.8808, "page": 0}, {"Word": ". Armltags, A. K ., ENL. O. H ., and Morrison, C. T ., Nature,237, 391 (1965).", "Confidence": 0.49494, "X1": 0.50809, "Y1": 0.8782, "X2": 0.9097, "Y2": 0.878, "X3": 0.9097, "Y3": 0.8898, "X4": 0.50809, "Y4": 0.8908, "page": 0}, {"Word": ". Kenbban. A ., Ballet, S ., Him bayashi, IL. Jeloberg, N. 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I", "Confidence": 0.58989, "X1": 0.53908, "Y1": 0.2312, "X2": 0.93531, "Y2": 0.231, "X3": 0.93531, "Y3": 0.2428, "X4": 0.53908, "Y4": 0.2418, "page": 0}, {"Word": "This article bas boun revised in the light of constructive", "Confidence": 0.6611, "X1": 0.11186, "Y1": 0.2382, "X2": 0.52022, "Y2": 0.238, "X3": 0.52022, "Y3": 0.2508, "X4": 0.11186, "Y4": 0.2498, "page": 0}, {"Word": "this is an error of study design such that the findings cano", "Confidence": 0.79042, "X1": 0.54043, "Y1": 0.2432, "X2": 0.93666, "Y2": 0.243, "X3": 0.93666, "Y3": 0.2548, "X4": 0.54043, "Y4": 0.2518, "page": 0}, {"Word": "criticisms from 4 refocco, but wems not to meet the following", "Confidence": 0.57364, "X1": 0.09704, "Y1": 0.2502, "X2": 0.52022, "Y2": 0.25, "X3": 0.52022, "Y3": 0.2618, "X4": 0.09704, "Y4": 0.2608, "page": 0}, {"Word": "interpreted with reference to long term effects of eigur", "Confidence": 0.66856, "X1": 0.531, "Y1": 0.2542, "X2": 0.93666, "Y2": 0.254, "X3": 0.93531, "Y3": 0.2658, "X4": 0.52965, "Y4": 0.2628, "page": 0}, {"Word": "cogent criticimme: \"From the average age of the subjects in the", "Confidence": 0.63118, "X1": 0.09704, "Y1": 0.2612, "X2": 0.51887, "Y2": 0.261, "X3": 0.51887, "Y3": 0.2728, "X4": 0.09704, "Y4": 0.2718, "page": 0}, {"Word": "smoking.\"-Editor.", "Confidence": 0.452, "X1": 0.53774, "Y1": 0.2612, "X2": 0.67116, "Y2": 0.261, "X3": 0.67116, "Y3": 0.2738, "X4": 0.53639, "Y4": 0.2728, "page": 0}, {"Word": "Absorption of Nicotine in Cigarette and Cigar Smoke", "Confidence": 0.99638, "X1": 0.09569, "Y1": 0.3532, "X2": 0.87062, "Y2": 0.353, "X3": 0.87062, "Y3": 0.3798, "X4": 0.09569, "Y4": 0.3758, "page": 0}, {"Word": "2074173713", "Confidence": 0.993, "X1": 0.97978, "Y1": 0.3892, "X2": 0.97305, "Y2": 0.389, "X3": 0.95148, "Y3": 0.3878, "X4": 0.95822, "Y4": 0.2878, "page": 0}, {"Word": "through the Oral Mucosa", "Confidence": 0.99375, "X1": 0.09569, "Y1": 0.3752, "X2": 0.45822, "Y2": 0.375, "X3": 0.45822, "Y3": 0.3998, "X4": 0.09569, "Y4": 0.3998, "page": 0}, {"Word": "by", "Confidence": 0.997, "X1": 0.09434, "Y1": 0.4152, "X2": 0.1159, "Y2": 0.415, "X3": 0.11456, "Y3": 0.4298, "X4": 0.09299, "Y4": 0.4298, "page": 0}, {"Word": "Nicotine in cigar smoke (pH 8.5) is much more readily absorb", "Confidence": 0.86718, "X1": 0.43531, "Y1": 0.4242, "X2": 0.93935, "Y2": 0.424, "X3": 0.93935, "Y3": 0.4408, "X4": 0.43531, "Y4": 0.4378, "page": 0}, {"Word": "A. K. ARMITAGE", "Confidence": 0.982, "X1": 0.09164, "Y1": 0.4342, "X2": 0.2372, "Y2": 0.434, "X3": 0.2372, "Y3": 0.4498, "X4": 0.09164, "Y4": 0.4508, "page": 0}, {"Word": "through the mucous membranes of the mouth than is nicotine", "Confidence": 0.9455, "X1": 0.43531, "Y1": 0.4402, "X2": 0.93531, "Y2": 0.44, "X3": 0.93531, "Y3": 0.4538, "X4": 0.43531, "Y4": 0.4508, "page": 0}, {"Word": "D. M. TURNER", "Confidence": 0.79167, "X1": 0.0903, "Y1": 0.4492, "X2": 0.21968, "Y2": 0.449, "X3": 0.21833, "Y3": 0.4638, "X4": 0.0903, "Y4": 0.4618, "page": 0}, {"Word": "cigarette smoke (pH 5.3) because there Is a higher concentration", "Confidence": 0.8544, "X1": 0.42992, "Y1": 0.4532, "X2": 0.93801, "Y2": 0.453, "X3": 0.93801, "Y3": 0.4668, "X4": 0.42992, "Y4": 0.4648, "page": 0}, {"Word": "Caparament of Pharmacology.", "Confidence": 0.73733, "X1": 0.09164, "Y1": 0.4692, "X2": 0.29784, "Y2": 0.469, "X3": 0.29784, "Y3": 0.4808, "X4": 0.09164, "Y4": 0.4798, "page": 0}, {"Word": "unionized nicotine in che relatively alkaline cigar smoke.", "Confidence": 0.83588, "X1": 0.43396, "Y1": 0.4662, "X2": 0.87871, "Y2": 0.466, "X3": 0.87871, "Y3": 0.4808, "X4": 0.43396, "Y4": 0.4778, "page": 0}, {"Word": "10 ::= Research Council Laboratories", "Confidence": 0.4392, "X1": 0.09164, "Y1": 0.4782, "X2": 0.35714, "Y2": 0.478, "X3": 0.35714, "Y3": 0.4908, "X4": 0.09164, "Y4": 0.4908, "page": 0}, {"Word": "A CIGARETTE smoker who inhales will obtain a dose of", "Confidence": 0.8448, "X1": 0.0876, "Y1": 0.5142, "X2": 0.51752, "Y2": 0.514, "X3": 0.51617, "Y3": 0.5298, "X4": 0.0876, "Y4": 0.5288, "page": 0}, {"Word": "and the largest 125 mm Hg. Ear twitching occurred", "Confidence": 0.78867, "X1": 0.52426, "Y1": 0.5182, "X2": 0.93666, "Y2": 0.518, "X3": 0.93666, "Y3": 0.5318, "X4": 0.52426, "Y4": 0.5298, "page": 0}, {"Word": "nicotine, during the five or ten minutes ho is smoking his", "Confidence": 0.77509, "X1": 0.0903, "Y1": 0.5272, "X2": 0.51482, "Y2": 0.527, "X3": 0.51482, "Y3": 0.5418, "X4": 0.0903, "Y4": 0.5418, "page": 0}, {"Word": "Sve of the experiments with cigar smoke; it began towar", "Confidence": 0.7451, "X1": 0.52426, "Y1": 0.5302, "X2": 0.9434, "Y2": 0.53, "X3": 0.9434, "Y3": 0.5438, "X4": 0.52426, "Y4": 0.5418, "page": 0}, {"Word": "cigarette, equivalent to a series of intravenous injections", "Confidence": 0.81938, "X1": 0.08895, "Y1": 0.5412, "X2": 0.51348, "Y2": 0.541, "X3": 0.51348, "Y3": 0.5538, "X4": 0.08895, "Y4": 0.5538, "page": 0}, {"Word": "the end of the smoke administration period and persiste", "Confidence": 0.90833, "X1": 0.52561, "Y1": 0.5422, "X2": 0.94474, "Y2": 0.542, "X3": 0.94474, "Y3": 0.5558, "X4": 0.52561, "Y4": 0.5538, "page": 0}, {"Word": "between 1 and 2 ug/kgt. Such a dose of nicotine may", "Confidence": 0.77445, "X1": 0.0876, "Y1": 0.5532, "X2": 0.51617, "Y2": 0.553, "X3": 0.51617, "Y3": 0.5658, "X4": 0.0876, "Y4": 0.5648, "page": 0}, {"Word": "for approximately ten minutes. These obrervations ind", "Confidence": 0.72229, "X1": 0.52561, "Y1": 0.5542, "X2": 0.9434, "Y2": 0.554, "X3": 0.9434, "Y3": 0.5668, "X4": 0.52561, "Y4": 0.5658, "page": 0}, {"Word": "well result in increased alertness\". It is usually believed", "Confidence": 0.80211, "X1": 0.0876, "Y1": 0.5642, "X2": 0.51213, "Y2": 0.564, "X3": 0.51213, "Y3": 0.5768, "X4": 0.0876, "Y4": 0.5768, "page": 0}, {"Word": "caso that there was a gradual socumulation of nicotine :", "Confidence": 0.7104, "X1": 0.52695, "Y1": 0.5652, "X2": 0.94474, "Y2": 0.565, "X3": 0.94474, "Y3": 0.5788, "X4": 0.52695, "Y4": 0.5778, "page": 0}, {"Word": "that the majority of cigarette smokers inhale to varying", "Confidence": 0.84456, "X1": 0.0876, "Y1": 0.5762, "X2": 0.51213, "Y2": 0.576, "X3": 0.51213, "Y3": 0.5888, "X4": 0.0876, "Y4": 0.5888, "page": 0}, {"Word": "the brain followed by gradual decline. Fig. 16 shows 1}", "Confidence": 0.6639, "X1": 0.5283, "Y1": 0.5762, "X2": 0.94474, "Y2": 0.576, "X3": 0.94474, "Y3": 0.5908, "X4": 0.5283, "Y4": 0.5898, "page": 0}, {"Word": "degrees the smoke which they take into their mouths,", "Confidence": 0.90744, "X1": 0.0876, "Y1": 0.5882, "X2": 0.51078, "Y2": 0.588, "X3": 0.51078, "Y3": 0.6008, "X4": 0.0876, "Y4": 0.6008, "page": 0}, {"Word": "slow rise in blood pressure caused by thirty 95 ml. puf", "Confidence": 0.79418, "X1": 0.531, "Y1": 0.5892, "X2": 0.94609, "Y2": 0.589, "X3": 0.94609, "Y3": 0.6028, "X4": 0.531, "Y4": 0.6018, "page": 0}, {"Word": "whereas the majority of cigar smokers do not. The ques-", "Confidence": 0.8192, "X1": 0.08625, "Y1": 0.6012, "X2": 0.51078, "Y2": 0.601, "X3": 0.51078, "Y3": 0.6138, "X4": 0.08625, "Y4": 0.6128, "page": 0}, {"Word": "of cigar smoke introduced into the mouth during 14.5 mis", "Confidence": 0.8453, "X1": 0.5283, "Y1": 0.6012, "X2": 0.94744, "Y2": 0.601, "X3": 0.94744, "Y3": 0.6138, "X4": 0.5283, "Y4": 0.6138, "page": 0}, {"Word": "tion than arises, does a cigar smoker who does not inhale", "Confidence": 0.754, "X1": 0.0876, "Y1": 0.6122, "X2": 0.51482, "Y2": 0.612, "X3": 0.51482, "Y3": 0.6258, "X4": 0.0876, "Y4": 0.6248, "page": 0}, {"Word": "A similar quantity of cigarette smoke, however, had n", "Confidence": 0.67822, "X1": 0.531, "Y1": 0.6132, "X2": 0.94609, "Y2": 0.613, "X3": 0.94609, "Y3": 0.6268, "X4": 0.531, "Y4": 0.6258, "page": 0}, {"Word": "Set a similar dose of nicotice to a cigarette smoker who", "Confidence": 0.59745, "X1": 0.08625, "Y1": 0.6252, "X2": 0.51348, "Y2": 0.625, "X3": 0.51348, "Y3": 0.6378, "X4": 0.08625, "Y4": 0.6378, "page": 0}, {"Word": "effect on blood pressure (Fig. la).", "Confidence": 0.78, "X1": 0.531, "Y1": 0.6262, "X2": 0.77493, "Y2": 0.626, "X3": 0.77493, "Y3": 0.6388, "X4": 0.531, "Y4": 0.6368, "page": 0}, {"Word": "ichales ? Kershbaum et al.' concluded that he does not,", "Confidence": 0.5537, "X1": 0.08625, "Y1": 0.6372, "X2": 0.50943, "Y2": 0.637, "X3": 0.50943, "Y3": 0.6498, "X4": 0.08625, "Y4": 0.6488, "page": 0}, {"Word": "Standard cigarettes manufactured from a flue-cure!", "Confidence": 0.82967, "X1": 0.54582, "Y1": 0.6352, "X2": 0.95013, "Y2": 0.635, "X3": 0.95013, "Y3": 0.6498, "X4": 0.54582, "Y4": 0.6498, "page": 0}, {"Word": "because they found that cigarette smokers excreted more", "Confidence": 0.85362, "X1": 0.0876, "Y1": 0.6482, "X2": 0.51617, "Y2": 0.648, "X3": 0.51617, "Y3": 0.6618, "X4": 0.0876, "Y4": 0.6618, "page": 0}, {"Word": "blend of tobacco (T 29), and standard cigars (C 1), wer", "Confidence": 0.79036, "X1": 0.52965, "Y1": 0.6492, "X2": 0.94744, "Y2": 0.649, "X3": 0.94609, "Y3": 0.6618, "X4": 0.52965, "Y4": 0.6608, "page": 0}, {"Word": "nicotine in the urine during a 4 h period of smoking than", "Confidence": 0.75425, "X1": 0.08491, "Y1": 0.6612, "X2": 0.51078, "Y2": 0.661, "X3": 0.51078, "Y3": 0.6738, "X4": 0.08491, "Y4": 0.6728, "page": 0}, {"Word": "smoked in the simulator at & rate of one puff every 30 !", "Confidence": 0.73569, "X1": 0.52695, "Y1": 0.6612, "X2": 0.95283, "Y2": 0.661, "X3": 0.95283, "Y3": 0.6738, "X4": 0.52695, "Y4": 0.6738, "page": 0}, {"Word": "did cigar mokers. The object of the experimenta de-", "Confidence": 0.891, "X1": 0.08625, "Y1": 0.6732, "X2": 0.51617, "Y2": 0.673, "X3": 0.51617, "Y3": 0.6858, "X4": 0.08625, "Y4": 0.6848, "page": 0}, {"Word": "The whole of each 25 ml. puff was collected on & Carr", "Confidence": 0.74283, "X1": 0.52695, "Y1": 0.6732, "X2": 0.94744, "Y2": 0.673, "X3": 0.94744, "Y3": 0.6858, "X4": 0.52695, "Y4": 0.6848, "page": 0}, {"Word": "seribed hero was to ascertain more directly the degree, and", "Confidence": 0.7884, "X1": 0.08356, "Y1": 0.6852, "X2": 0.51078, "Y2": 0.685, "X3": 0.51078, "Y3": 0.6978, "X4": 0.08356, "Y4": 0.6968, "page": 0}, {"Word": "bridge glow-fibro filter disk and the Siters were analyse", "Confidence": 0.72222, "X1": 0.52695, "Y1": 0.6852, "X2": 0.94744, "Y2": 0.685, "X3": 0.94744, "Y3": 0.6988, "X4": 0.52695, "Y4": 0.6988, "page": 0}, {"Word": "particularly the rate, of absorption of nicotine in cigarette", "Confidence": 0.82144, "X1": 0.08491, "Y1": 0.6972, "X2": 0.50943, "Y2": 0.697, "X3": 0.50943, "Y3": 0.7108, "X4": 0.08491, "Y4": 0.7108, "page": 0}, {"Word": "for nicotine by a method based on that of Willits of al.\"", "Confidence": 0.75642, "X1": 0.52561, "Y1": 0.6972, "X2": 0.94609, "Y2": 0.697, "X3": 0.94609, "Y3": 0.7098, "X4": 0.52561, "Y4": 0.7108, "page": 0}, {"Word": "and cigar moks through the on] mucosa.", "Confidence": 0.77529, "X1": 0.08625, "Y1": 0.7092, "X2": 0.40566, "Y2": 0.709, "X3": 0.40566, "Y3": 0.7208, "X4": 0.08625, "Y4": 0.7198, "page": 0}, {"Word": "The average nicotine content of twenty puffs of cigarett", "Confidence": 0.86578, "X1": 0.52695, "Y1": 0.7092, "X2": 0.94609, "Y2": 0.709, "X3": 0.94609, "Y3": 0.7218, "X4": 0.52695, "Y4": 0.7218, "page": 0}, {"Word": "Cata, ansesthetized with chloralose, bad the trachea and", "Confidence": 0.76963, "X1": 0.10108, "Y1": 0.7192, "X2": 0.51078, "Y2": 0.719, "X3": 0.51078, "Y3": 0.7338, "X4": 0.10108, "Y4": 0.7328, "page": 0}, {"Word": "smoke was 3-33 mg, and of thirty puffs i.44 mg, and wa.", "Confidence": 0.68467, "X1": 0.52695, "Y1": 0.7212, "X2": 0.94879, "Y2": 0.721, "X3": 0.94879, "Y3": 0.7348, "X4": 0.52695, "Y4": 0.7338, "page": 0}, {"Word": "oesophagus tied high in the neck. Breathing occurred", "Confidence": 0.83025, "X1": 0.08491, "Y1": 0.7322, "X2": 0.50943, "Y2": 0.732, "X3": 0.50943, "Y3": 0.7448, "X4": 0.08491, "Y4": 0.7448, "page": 0}, {"Word": "in fact greater than that of the same number of puffs o", "Confidence": 0.87067, "X1": 0.5283, "Y1": 0.7322, "X2": 0.94609, "Y2": 0.732, "X3": 0.94609, "Y3": 0.7458, "X4": 0.5283, "Y4": 0.7458, "page": 0}, {"Word": "through a tube inserted in the trachea. 25 ml. of tobacco", "Confidence": 0.86082, "X1": 0.08356, "Y1": 0.7442, "X2": 0.50943, "Y2": 0.744, "X3": 0.50943, "Y3": 0.7558, "X4": 0.08356, "Y4": 0.7558, "page": 0}, {"Word": "cigar amoke (2.32 and <- 00 mg respectively). Yet the", "Confidence": 0.7321, "X1": 0.52695, "Y1": 0.7432, "X2": 0.94879, "Y2": 0.743, "X3": 0.94879, "Y3": 0.7578, "X4": 0.52695, "Y4": 0.7588, "page": 0}, {"Word": "smoke was introduced into the mouth overy 30 a from a", "Confidence": 0.83218, "X1": 0.08356, "Y1": 0.7562, "X2": 0.51078, "Y2": 0.756, "X3": 0.51078, "Y3": 0.7688, "X4": 0.08356, "Y4": 0.7678, "page": 0}, {"Word": "cigar smoke invariably caused a bigger pharmacologics", "Confidence": 0.697, "X1": 0.52561, "Y1": 0.7562, "X2": 0.94879, "Y2": 0.756, "X3": 0.94879, "Y3": 0.7698, "X4": 0.52561, "Y4": 0.7698, "page": 0}, {"Word": "smoking simulator through a thin rubber dam held", "Confidence": 0.76413, "X1": 0.08356, "Y1": 0.7682, "X2": 0.50943, "Y2": 0.768, "X3": 0.50943, "Y3": 0.7798, "X4": 0.08356, "Y4": 0.7798, "page": 0}, {"Word": "response. What is the explanation of this apparent", "Confidence": 0.814, "X1": 0.52426, "Y1": 0.7672, "X2": 0.95013, "Y2": 0.767, "X3": 0.95013, "Y3": 0.7808, "X4": 0.52426, "Y4": 0.7808, "page": 0}, {"Word": "firmly in position over the mouth by artery clips. After", "Confidence": 0.8186, "X1": 0.08086, "Y1": 0.7792, "X2": 0.50943, "Y2": 0.779, "X3": 0.50943, "Y3": 0.7928, "X4": 0.08086, "Y4": 0.7918, "page": 0}, {"Word": "Anomaly T.", "Confidence": 0.568, "X1": 0.52695, "Y1": 0.7822, "X2": 0.62399, "Y2": 0.782, "X3": 0.62264, "Y3": 0.7948, "X4": 0.52561, "Y4": 0.7918, "page": 0}, {"Word": "10 s the moke was blown out. The changes in blood", "Confidence": 0.82982, "X1": 0.08221, "Y1": 0.7912, "X2": 0.51078, "Y2": 0.791, "X3": 0.51078, "Y3": 0.8028, "X4": 0.08221, "Y4": 0.8028, "page": 0}, {"Word": "One of the most striking differences between cigarette", "Confidence": 0.87475, "X1": 0.54313, "Y1": 0.7892, "X2": 0.94879, "Y2": 0.789, "X3": 0.94879, "Y3": 0.8028, "X4": 0.54313, "Y4": 0.8038, "page": 0}, {"Word": "pressure and movements of the cat's ears caused by", "Confidence": 0.794, "X1": 0.08086, "Y1": 0.8022, "X2": 0.50809, "Y2": 0.802, "X3": 0.50809, "Y3": 0.8158, "X4": 0.08086, "Y4": 0.8158, "page": 0}, {"Word": "and cigar smoke is the pH of the amoke. 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The buffer", "Confidence": 0.74092, "X1": 0.52156, "Y1": 0.8252, "X2": 0.95148, "Y2": 0.825, "X3": 0.95148, "Y3": 0.8388, "X4": 0.52156, "Y4": 0.8398, "page": 0}, {"Word": "onrs is an action which is highly specific for nicotine and", "Confidence": 0.84118, "X1": 0.08221, "Y1": 0.8372, "X2": 0.50943, "Y2": 0.837, "X3": 0.50943, "Y3": 0.8488, "X4": 0.08221, "Y4": 0.8498, "page": 0}, {"Word": "capacity of the two smokes was about the same. 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{"Word": "1964-1978", "Confidence": 0.981, "X1": 0.27851, "Y1": 0.3412, "X2": 0.38462, "Y2": 0.341, "X3": 0.38462, "Y3": 0.3548, "X4": 0.27851, "Y4": 0.3548, "page": 0, "Index": 23}, {"Word": "Sales", "Confidence": 0.992, "X1": 0.21883, "Y1": 0.3712, "X2": 0.27586, "Y2": 0.371, "X3": 0.27586, "Y3": 0.3848, "X4": 0.21883, "Y4": 0.3848, "page": 0, "Index": 24}, {"Word": "1981-", "Confidence": 0.993, "X1": 0.27851, "Y1": 0.3992, "X2": 0.33687, "Y2": 0.399, "X3": 0.33687, "Y3": 0.4138, "X4": 0.27851, "Y4": 0.4138, "page": 0, "Index": 25}, {"Word": "1972-1980", "Confidence": 0.992, "X1": 0.27851, "Y1": 0.4282, "X2": 0.38462, "Y2": 0.428, "X3": 0.38462, "Y3": 0.4438, "X4": 0.27851, "Y4": 0.4438, "page": 0, "Index": 26}, {"Word": "1959-1971", "Confidence": 0.981, "X1": 0.27719, "Y1": 0.4572, "X2": 0.38594, "Y2": 0.457, "X3": 0.38462, "Y3": 0.4738, "X4": 0.27719, "Y4": 0.4738, "page": 0, "Index": 27}, {"Word": "Bans", "Confidence": 0.987, "X1": 0.27719, "Y1": 0.4902, "X2": 0.32493, "Y2": 0.49, 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{"Word": "Wharton", "Confidence": 0.995, "X1": 0.27719, "Y1": 0.8142, "X2": 0.36472, "Y2": 0.814, "X3": 0.3634, "Y3": 0.8298, "X4": 0.27586, "Y4": 0.8308, "page": 0, "Index": 56}, {"Word": "Reports", "Confidence": 0.995, "X1": 0.37268, "Y1": 0.8142, "X2": 0.45889, "Y2": 0.814, "X3": 0.45889, "Y3": 0.8308, "X4": 0.37135, "Y4": 0.8308, "page": 0, "Index": 57}, {"Word": "('52/'63)", "Confidence": 0.936, "X1": 0.47082, "Y1": 0.8142, "X2": 0.57692, "Y2": 0.814, "X3": 0.5756, "Y3": 0.8338, "X4": 0.4695, "Y4": 0.8308, "page": 0, "Index": 58}, {"Word": "TI4887048", "Confidence": 0.666, "X1": 0.89788, "Y1": 0.9762, "X2": 0.99735, "Y2": 0.976, "X3": 0.99735, "Y3": 0.9918, "X4": 0.8992, "Y4": 0.9918, "page": 0, "Index": 59}]} | null |
ffnb0048 | 1 | {"lines_data": [{"Word": "Brunnemann, Scott, and Hoffmann", "Confidence": 0.92425, "X1": 0.67712, "Y1": 0.0142, "X2": 0.87974, "Y2": 0.014, "X3": 0.87974, "Y3": 0.0278, "X4": 0.67582, "Y4": 0.0268, "page": 0}, {"Word": "906 J. Agric. Food Chem ., Voll 31, No. 4, 1983", "Confidence": 0.80164, "X1": 0.06405, "Y1": 0.0142, "X2": 0.35556, "Y2": 0.014, "X3": 0.35556, "Y3": 0.0288, "X4": 0.06405, "Y4": 0.0298, "page": 0}, {"Word": "Recently, N-nitrosoproline (NPRO) has become an im-", "Confidence": 0.958, "X1": 0.07843, "Y1": 0.0392, "X2": 0.45229, "Y2": 0.039, "X3": 0.45229, "Y3": 0.0538, "X4": 0.07843, "Y4": 0.0528, "page": 0}, {"Word": "\u00d7 1/4 in. o.d. 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NPRO is formed", "Confidence": 0.98622, "X1": 0.06667, "Y1": 0.0782, "X2": 0.45359, "Y2": 0.078, "X3": 0.45359, "Y3": 0.0918, "X4": 0.06667, "Y4": 0.0928, "page": 0}, {"Word": "For the mass spectral identification of NPRO, 100 g of", "Confidence": 0.9848, "X1": 0.50196, "Y1": 0.0772, "X2": 0.88105, "Y2": 0.077, "X3": 0.88105, "Y3": 0.0918, "X4": 0.50196, "Y4": 0.0928, "page": 0}, {"Word": "in man by endogenous N-nitrosation of proline and is", "Confidence": 0.96178, "X1": 0.06667, "Y1": 0.0912, "X2": 0.45752, "Y2": 0.091, "X3": 0.45752, "Y3": 0.1058, "X4": 0.06667, "Y4": 0.1058, "page": 0}, {"Word": "snuff tobacco was extracted in 2000 mL of water and the", "Confidence": 0.953, "X1": 0.48889, "Y1": 0.0912, "X2": 0.88366, "Y2": 0.091, "X3": 0.88366, "Y3": 0.1048, "X4": 0.48889, "Y4": 0.1058, "page": 0}, {"Word": "extract was worked up as described under Determination", "Confidence": 0.9665, "X1": 0.48627, "Y1": 0.1052, "X2": 0.87974, "Y2": 0.105, "X3": 0.87974, "Y3": 0.1178, "X4": 0.48627, "Y4": 0.1198, "page": 0}, {"Word": "excreted in the urine in unchanged form (Ohshima and", "Confidence": 0.99489, "X1": 0.06536, "Y1": 0.1052, "X2": 0.4549, "Y2": 0.105, "X3": 0.4549, "Y3": 0.1198, "X4": 0.06536, "Y4": 0.1198, "page": 0}, {"Word": "Bartsch, 1981). 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The radioactive fraction was", "Confidence": 0.96333, "X1": 0.48758, "Y1": 0.1442, "X2": 0.87974, "Y2": 0.144, "X3": 0.87974, "Y3": 0.1578, "X4": 0.48758, "Y4": 0.1588, "page": 0}, {"Word": "urine of some cigarette smokers than in urine of non-", "Confidence": 0.9701, "X1": 0.06667, "Y1": 0.1462, "X2": 0.45229, "Y2": 0.146, "X3": 0.45229, "Y3": 0.1588, "X4": 0.06667, "Y4": 0.1588, "page": 0}, {"Word": "smokers (Hoffmann et al, 1983); thus, we questioned", "Confidence": 0.958, "X1": 0.06536, "Y1": 0.1592, "X2": 0.4549, "Y2": 0.159, "X3": 0.45359, "Y3": 0.1728, "X4": 0.06536, "Y4": 0.1718, "page": 0}, {"Word": "purified by preparative TLC. After extraction of the", "Confidence": 0.97375, "X1": 0.48758, "Y1": 0.1572, "X2": 0.87974, "Y2": 0.157, "X3": 0.87974, "Y3": 0.1718, "X4": 0.48758, "Y4": 0.1728, "page": 0}, {"Word": "whether tobacco products contain NPRO. It was the goal", "Confidence": 0.96933, "X1": 0.06797, "Y1": 0.1712, "X2": 0.45752, "Y2": 0.171, "X3": 0.45752, "Y3": 0.1858, "X4": 0.06797, "Y4": 0.1858, "page": 0}, {"Word": "NPRO band, the final fraction was further concentrated", "Confidence": 0.99113, "X1": 0.48758, "Y1": 0.1692, "X2": 0.88105, "Y2": 0.169, "X3": 0.88105, "Y3": 0.1848, "X4": 0.48758, "Y4": 0.1838, "page": 0}, {"Word": "and methylated prior to GC-MS identification. We used", "Confidence": 0.98587, "X1": 0.4902, "Y1": 0.1832, "X2": 0.87712, "Y2": 0.183, "X3": 0.87712, "Y3": 0.1978, "X4": 0.4902, "Y4": 0.1988, "page": 0}, {"Word": "of this study to explore the possible presence of NPRO in", "Confidence": 0.98873, "X1": 0.06536, "Y1": 0.1842, "X2": 0.45621, "Y2": 0.184, "X3": 0.45621, "Y3": 0.1988, "X4": 0.06536, "Y4": 0.1988, "page": 0}, {"Word": "-", "Confidence": 0.99, "X1": 0.89542, "Y1": 0.1932, "X2": 0.91895, "Y2": 0.193, "X3": 0.91765, "Y3": 0.2018, "X4": 0.89542, "Y4": 0.2008, "page": 0}, {"Word": "tobacco and tobacco smoke and to investigate whether this", "Confidence": 0.95589, "X1": 0.06667, "Y1": 0.1982, "X2": 0.4549, "Y2": 0.198, "X3": 0.4549, "Y3": 0.2128, "X4": 0.06667, "Y4": 0.2128, "page": 0}, {"Word": "a 25 m X: 0.24 mm (i.d.) fused silica capillary column", "Confidence": 0.96564, "X1": 0.48627, "Y1": 0.1972, "X2": 0.87712, "Y2": 0.197, "X3": 0.87712, "Y3": 0.2118, "X4": 0.48627, "Y4": 0.2118, "page": 0}, {"Word": "compound could serve as an indicator for the formation", "Confidence": 0.94989, "X1": 0.06667, "Y1": 0.2122, "X2": 0.46013, "Y2": 0.212, "X3": 0.46013, "Y3": 0.2248, "X4": 0.06667, "Y4": 0.2258, "page": 0}, {"Word": "(WCOT) coated with chemically bonded methyl silicone", "Confidence": 0.95443, "X1": 0.48889, "Y1": 0.2102, "X2": 0.88105, "Y2": 0.21, "X3": 0.88105, "Y3": 0.2248, "X4": 0.48889, "Y4": 0.2248, "page": 0}, {"Word": "of TSNA during tobacco processing and smoking. The", "Confidence": 0.947, "X1": 0.06667, "Y1": 0.2242, "X2": 0.45752, "Y2": 0.224, "X3": 0.45752, "Y3": 0.2398, "X4": 0.06667, "Y4": 0.2388, "page": 0}, {"Word": "(film thickness 0.25 um). The GC program was 4 min at", "Confidence": 0.96091, "X1": 0.48627, "Y1": 0.2242, "X2": 0.87974, "Y2": 0.224, "X3": 0.87974, "Y3": 0.2388, "X4": 0.48627, "Y4": 0.2378, "page": 0}, {"Word": "advantage of measuring N-nitrosation potential by de-", "Confidence": 0.99429, "X1": 0.06405, "Y1": 0.2372, "X2": 0.46013, "Y2": 0.237, "X3": 0.46013, "Y3": 0.2518, "X4": 0.06405, "Y4": 0.2528, "page": 0}, {"Word": "50 \u2103 and then 2 \u2103/min to 250 \u2103. Under these con-", "Confidence": 0.917, "X1": 0.48889, "Y1": 0.2382, "X2": 0.87974, "Y2": 0.238, "X3": 0.87974, "Y3": 0.2528, "X4": 0.48889, "Y4": 0.2518, "page": 0}, {"Word": "termining the noncarcinogenic N-nitrosoproline lies in", "Confidence": 0.9785, "X1": 0.06405, "Y1": 0.2502, "X2": 0.4549, "Y2": 0.25, "X3": 0.45621, "Y3": 0.2648, "X4": 0.06405, "Y4": 0.2658, "page": 0}, {"Word": "ditions, the methyl ester of NPRO had a retention time", "Confidence": 0.9936, "X1": 0.48889, "Y1": 0.2512, "X2": 0.87974, "Y2": 0.251, "X3": 0.87974, "Y3": 0.2648, "X4": 0.48889, "Y4": 0.2648, "page": 0}, {"Word": "of 11.3 min.", "Confidence": 0.99033, "X1": 0.48889, "Y1": 0.2642, "X2": 0.57647, "Y2": 0.264, "X3": 0.57647, "Y3": 0.2778, "X4": 0.48889, "Y4": 0.2778, "page": 0}, {"Word": "avoiding the carcinogenic tobacco-specific N-nitrosamines", "Confidence": 0.9004, "X1": 0.06667, "Y1": 0.2652, "X2": 0.45621, "Y2": 0.265, "X3": 0.45621, "Y3": 0.2788, "X4": 0.06667, "Y4": 0.2788, "page": 0}, {"Word": "for which reference compounds are not always readily", "Confidence": 0.99562, "X1": 0.06667, "Y1": 0.2782, "X2": 0.45359, "Y2": 0.278, "X3": 0.45359, "Y3": 0.2918, "X4": 0.06667, "Y4": 0.2918, "page": 0}, {"Word": "Determination of Proline in Tobacco as N-", "Confidence": 0.93671, "X1": 0.50327, "Y1": 0.2762, "X2": 0.87974, "Y2": 0.276, "X3": 0.87974, "Y3": 0.2918, "X4": 0.50327, "Y4": 0.2918, "page": 0}, {"Word": "available.", "Confidence": 0.851, "X1": 0.06405, "Y1": 0.2912, "X2": 0.13333, "Y2": 0.291, "X3": 0.13333, "Y3": 0.3028, "X4": 0.06405, "Y4": 0.3038, "page": 0}, {"Word": "Nitrosoproline (NPRO). One gram of processed tobacco", "Confidence": 0.86871, "X1": 0.4902, "Y1": 0.2902, "X2": 0.87974, "Y2": 0.29, "X3": 0.87974, "Y3": 0.3048, "X4": 0.4902, "Y4": 0.3038, "page": 0}, {"Word": "was stirred for 2 h with 50 ml of water containing 1 g of", "Confidence": 0.98579, "X1": 0.48758, "Y1": 0.3032, "X2": 0.88235, "Y2": 0.303, "X3": 0.88235, "Y3": 0.3178, "X4": 0.48758, "Y4": 0.3168, "page": 0}, {"Word": "EXPERIMENTAL SECTION", "Confidence": 0.9935, "X1": 0.06536, "Y1": 0.3102, "X2": 0.26275, "Y2": 0.31, "X3": 0.26275, "Y3": 0.3248, "X4": 0.06536, "Y4": 0.3248, "page": 0}, {"Word": "NaNO, 2 mL of 1 N acetic acid, and 1 mL of proline-U-MC", "Confidence": 0.93146, "X1": 0.48889, "Y1": 0.3162, "X2": 0.87843, "Y2": 0.316, "X3": 0.87843, "Y3": 0.3298, "X4": 0.48889, "Y4": 0.3298, "page": 0}, {"Word": "Materials. All commercial tobacco products were", "Confidence": 0.96483, "X1": 0.08235, "Y1": 0.3282, "X2": 0.45752, "Y2": 0.328, "X3": 0.45752, "Y3": 0.3438, "X4": 0.08105, "Y4": 0.3428, "page": 0}, {"Word": "(84 000 dpm/19 ng). The determination of proline as", "Confidence": 0.77811, "X1": 0.48627, "Y1": 0.3292, "X2": 0.88105, "Y2": 0.329, "X3": 0.88105, "Y3": 0.3438, "X4": 0.48627, "Y4": 0.3428, "page": 0}, {"Word": "purchased on the open market in Westchester County, NY,", "Confidence": 0.969, "X1": 0.06536, "Y1": 0.3422, "X2": 0.45752, "Y2": 0.342, "X3": 0.45752, "Y3": 0.3568, "X4": 0.06536, "Y4": 0.3578, "page": 0}, {"Word": "NPRO was then carried out with the analytical procedure", "Confidence": 0.98478, "X1": 0.4902, "Y1": 0.3432, "X2": 0.87843, "Y2": 0.343, "X3": 0.87843, "Y3": 0.3568, "X4": 0.4902, "Y4": 0.3558, "page": 0}, {"Word": "during 1982. Green Burley 21 tobacco plants were made", "Confidence": 0.97478, "X1": 0.06797, "Y1": 0.3552, "X2": 0.45621, "Y2": 0.355, "X3": 0.45621, "Y3": 0.3688, "X4": 0.06797, "Y4": 0.3678, "page": 0}, {"Word": "described above. In the case of green tobacco we homo-", "Confidence": 0.9937, "X1": 0.4902, "Y1": 0.3562, "X2": 0.88105, "Y2": 0.356, "X3": 0.88105, "Y3": 0.3698, "X4": 0.4902, "Y4": 0.3698, "page": 0}, {"Word": "available by Dr. T. C. To, U.S. Department of Agriculture,", "Confidence": 0.9633, "X1": 0.06536, "Y1": 0.3682, "X2": 0.4549, "Y2": 0.368, "X3": 0.4549, "Y3": 0.3828, "X4": 0.06536, "Y4": 0.3818, "page": 0}, {"Word": "genized .25 g of leaves, immediately after their removal", "Confidence": 0.93133, "X1": 0.48366, "Y1": 0.3682, "X2": 0.88105, "Y2": 0.368, "X3": 0.88105, "Y3": 0.3828, "X4": 0.48366, "Y4": 0.3838, "page": 0}, {"Word": "Beltsville, MD. The leaves were harvested when the plants", "Confidence": 0.91456, "X1": 0.06667, "Y1": 0.3812, "X2": 0.46144, "Y2": 0.381, "X3": 0.46144, "Y3": 0.3948, "X4": 0.06667, "Y4": 0.3938, "page": 0}, {"Word": "from the stalk, in 150 ml of diluted AS solution (see", "Confidence": 0.97482, "X1": 0.48366, "Y1": 0.3812, "X2": 0.88235, "Y2": 0.381, "X3": 0.88235, "Y3": 0.3948, "X4": 0.48366, "Y4": 0.3958, "page": 0}, {"Word": "had reached maturity.", "Confidence": 0.82067, "X1": 0.06275, "Y1": 0.3952, "X2": 0.22353, "Y2": 0.395, "X3": 0.22353, "Y3": 0.4088, "X4": 0.06275, "Y4": 0.4058, "page": 0}, {"Word": "Determination of NPRO in Tobacco) in a blender. The", "Confidence": 0.99244, "X1": 0.48889, "Y1": 0.3952, "X2": 0.87974, "Y2": 0.395, "X3": 0.87974, "Y3": 0.4088, "X4": 0.48889, "Y4": 0.4088, "page": 0}, {"Word": "Chemicals. NPRO was synthesized from proline ac-", "Confidence": 0.99243, "X1": 0.08366, "Y1": 0.4072, "X2": 0.4549, "Y2": 0.407, "X3": 0.4549, "Y3": 0.4218, "X4": 0.08366, "Y4": 0.4208, "page": 0}, {"Word": "analysis was completed in the same manner as in the case", "Confidence": 0.99027, "X1": 0.48497, "Y1": 0.4082, "X2": 0.88366, "Y2": 0.408, "X3": 0.88366, "Y3": 0.4218, "X4": 0.48497, "Y4": 0.4228, "page": 0}, {"Word": "cording to Lijinsky et al. (1970). Its purity was ascertained", "Confidence": 0.8978, "X1": 0.06928, "Y1": 0.4212, "X2": 0.45621, "Y2": 0.421, "X3": 0.45621, "Y3": 0.4348, "X4": 0.06928, "Y4": 0.4338, "page": 0}, {"Word": "of processed tobacco.", "Confidence": 0.94067, "X1": 0.49281, "Y1": 0.4222, "X2": 0.64052, "Y2": 0.422, "X3": 0.64052, "Y3": 0.4358, "X4": 0.49281, "Y4": 0.4348, "page": 0}, {"Word": "by gas chromatography (GC) and mass spectrometry (MS).", "Confidence": 0.9715, "X1": 0.06275, "Y1": 0.4332, "X2": 0.45752, "Y2": 0.433, "X3": 0.45752, "Y3": 0.4478, "X4": 0.06275, "Y4": 0.4468, "page": 0}, {"Word": "Analysis of NPRO and N-Nitrosopyrrolidine in", "Confidence": 0.96967, "X1": 0.50065, "Y1": 0.4332, "X2": 0.87974, "Y2": 0.433, "X3": 0.87974, "Y3": 0.4478, "X4": 0.50065, "Y4": 0.4488, "page": 0}, {"Word": "The standard mixture of volatile N-nitrosamines was", "Confidence": 0.95743, "X1": 0.06536, "Y1": 0.4472, "X2": 0.45882, "Y2": 0.447, "X3": 0.45882, "Y3": 0.4608, "X4": 0.06536, "Y4": 0.4608, "page": 0}, {"Word": "Tobacco Smoke. For the untreated control, 100 cigarettes", "Confidence": 0.9225, "X1": 0.48889, "Y1": 0.4482, "X2": 0.87843, "Y2": 0.448, "X3": 0.87843, "Y3": 0.4618, "X4": 0.48758, "Y4": 0.4618, "page": 0}, {"Word": "purchased from Thermo Electron Corp ., Waltham, MA;", "Confidence": 0.98438, "X1": 0.06144, "Y1": 0.4592, "X2": 0.45752, "Y2": 0.459, "X3": 0.45752, "Y3": 0.4728, "X4": 0.06144, "Y4": 0.4738, "page": 0}, {"Word": "were smoked with a 20-unit automatic smoker (see Ap-", "Confidence": 0.96122, "X1": 0.4902, "Y1": 0.4602, "X2": 0.88366, "Y2": 0.46, "X3": 0.88366, "Y3": 0.4738, "X4": 0.4902, "Y4": 0.4748, "page": 0}, {"Word": ". the tobacco-specific N-nitrosamines (TSNA) were syn-", "Confidence": 0.80343, "X1": 0.05882, "Y1": 0.4722, "X2": 0.45882, "Y2": 0.472, "X3": 0.45882, "Y3": 0.4868, "X4": 0.05882, "Y4": 0.4868, "page": 0}, {"Word": "paratus) and the mainstream smoke was led through two", "Confidence": 0.98656, "X1": 0.48758, "Y1": 0.4732, "X2": 0.87974, "Y2": 0.473, "X3": 0.87974, "Y3": 0.4868, "X4": 0.48758, "Y4": 0.4878, "page": 0}, {"Word": "thesized according to earlier published methods (Hoffmann", "Confidence": 0.95457, "X1": 0.06667, "Y1": 0.4862, "X2": 0.45621, "Y2": 0.486, "X3": 0.45621, "Y3": 0.4998, "X4": 0.06667, "Y4": 0.4998, "page": 0}, {"Word": "gas wash bottles containing citrate buffer and 20 mM", "Confidence": 0.97456, "X1": 0.48627, "Y1": 0.4852, "X2": 0.88105, "Y2": 0.485, "X3": 0.88105, "Y3": 0.4998, "X4": 0.48627, "Y4": 0.5018, "page": 0}, {"Word": "et al ., 1979). L-Proline-U.14C (sp act. 250 Ci/MM) was", "Confidence": 0.8492, "X1": 0.06928, "Y1": 0.4992, "X2": 0.45882, "Y2": 0.499, "X3": 0.45752, "Y3": 0.5148, "X4": 0.06928, "Y4": 0.5128, "page": 0}, {"Word": "ascorbic acid (Hoffmann et al ., 1979) with NPRO-U-\"C", "Confidence": 0.91967, "X1": 0.48497, "Y1": 0.4972, "X2": 0.87974, "Y2": 0.497, "X3": 0.87974, "Y3": 0.5128, "X4": 0.48497, "Y4": 0.5148, "page": 0}, {"Word": "obtained from ICN, Irvine, CA, and 14% BF, in methanol", "Confidence": 0.9578, "X1": 0.06667, "Y1": 0.5122, "X2": 0.45621, "Y2": 0.512, "X3": 0.45621, "Y3": 0.5268, "X4": 0.06667, "Y4": 0.5258, "page": 0}, {"Word": "serving as the internal standard (96500 dpm/27 ng). After", "Confidence": 0.99056, "X1": 0.48497, "Y1": 0.5122, "X2": 0.88105, "Y2": 0.512, "X3": 0.88105, "Y3": 0.5268, "X4": 0.48497, "Y4": 0.5288, "page": 0}, {"Word": "from Pierce Chemical Co ., Rockford, IL.", "Confidence": 0.94614, "X1": 0.06797, "Y1": 0.5252, "X2": 0.35163, "Y2": 0.525, "X3": 0.35163, "Y3": 0.5388, "X4": 0.06797, "Y4": 0.5388, "page": 0}, {"Word": "addition of 80 g of NaCl, the buffer solution was extracted", "Confidence": 0.97418, "X1": 0.48889, "Y1": 0.5262, "X2": 0.87974, "Y2": 0.526, "X3": 0.87974, "Y3": 0.5398, "X4": 0.48889, "Y4": 0.5408, "page": 0}, {"Word": "Apparatus. A Model 543 thermal energy analyzer", "Confidence": 0.982, "X1": 0.07843, "Y1": 0.5392, "X2": 0.45752, "Y2": 0.539, "X3": 0.45752, "Y3": 0.5538, "X4": 0.07843, "Y4": 0.5528, "page": 0}, {"Word": "with ethyl acetate and the latter was dried (Na SO). After", "Confidence": 0.93355, "X1": 0.48627, "Y1": 0.5382, "X2": 0.87843, "Y2": 0.538, "X3": 0.87843, "Y3": 0.5528, "X4": 0.48627, "Y4": 0.5528, "page": 0}, {"Word": "(TEA) from the Thermo Electron Corp ., Waltham, MA,", "Confidence": 0.90633, "X1": 0.07059, "Y1": 0.5512, "X2": 0.45752, "Y2": 0.551, "X3": 0.45752, "Y3": 0.5648, "X4": 0.07059, "Y4": 0.5648, "page": 0}, {"Word": "concentration to 2 mL, the extract was further enriched", "Confidence": 0.98456, "X1": 0.48889, "Y1": 0.5522, "X2": 0.87843, "Y2": 0.552, "X3": 0.87843, "Y3": 0.5648, "X4": 0.48889, "Y4": 0.5668, "page": 0}, {"Word": "was interfaced directly with a Model 700 gas chromato-", "Confidence": 0.99044, "X1": 0.07059, "Y1": 0.5642, "X2": 0.45621, "Y2": 0.564, "X3": 0.45621, "Y3": 0.5788, "X4": 0.07059, "Y4": 0.5778, "page": 0}, {"Word": "by column chromatography (60 g of silica gel, mesh 40-140,", "Confidence": 0.9798, "X1": 0.4902, "Y1": 0.5652, "X2": 0.87974, "Y2": 0.565, "X3": 0.87974, "Y3": 0.5788, "X4": 0.4902, "Y4": 0.5798, "page": 0}, {"Word": "graph (Hewlett-Packard) by using modifications previously", "Confidence": 0.90783, "X1": 0.06797, "Y1": 0.5772, "X2": 0.4549, "Y2": 0.577, "X3": 0.4549, "Y3": 0.5918, "X4": 0.06797, "Y4": 0.5908, "page": 0}, {"Word": "Baker Chemicals) and then analyzed for NPRO (see De-", "Confidence": 0.98644, "X1": 0.4902, "Y1": 0.5772, "X2": 0.87974, "Y2": 0.577, "X3": 0.87974, "Y3": 0.5918, "X4": 0.4902, "Y4": 0.5918, "page": 0}, {"Word": "described (Brunnemann and Hoffmann, 1981). The mass", "Confidence": 0.935, "X1": 0.06928, "Y1": 0.5902, "X2": 0.45882, "Y2": 0.59, "X3": 0.45882, "Y3": 0.6038, "X4": 0.06928, "Y4": 0.6038, "page": 0}, {"Word": "termination of NPRO in Tobacco) and N-nitroso-", "Confidence": 0.98943, "X1": 0.4902, "Y1": 0.5912, "X2": 0.87974, "Y2": 0.591, "X3": 0.87974, "Y3": 0.6048, "X4": 0.4902, "Y4": 0.6048, "page": 0}, {"Word": "spectral analysis was done with a Hewlett-Packard Model", "Confidence": 0.98187, "X1": 0.06928, "Y1": 0.6022, "X2": 0.45752, "Y2": 0.602, "X3": 0.45882, "Y3": 0.6158, "X4": 0.06928, "Y4": 0.6178, "page": 0}, {"Word": "pyrrolidine (Brunnemann et al ., 1977). Only 10 cigarettes", "Confidence": 0.90489, "X1": 0.4902, "Y1": 0.6042, "X2": 0.87974, "Y2": 0.604, "X3": 0.87974, "Y3": 0.6188, "X4": 0.4902, "Y4": 0.6188, "page": 0}, {"Word": "5982 GC-MS instrument. Cigarettes were smoked with", "Confidence": 0.97714, "X1": 0.07059, "Y1": 0.6152, "X2": 0.45621, "Y2": 0.615, "X3": 0.45621, "Y3": 0.6298, "X4": 0.07059, "Y4": 0.6288, "page": 0}, {"Word": "per analysis were smoked in the case of applications of 5", "Confidence": 0.97273, "X1": 0.4902, "Y1": 0.6172, "X2": 0.87974, "Y2": 0.617, "X3": 0.87974, "Y3": 0.6308, "X4": 0.4902, "Y4": 0.6318, "page": 0}, {"Word": "a 20-port automatic smoker with 'a rotating head (H.", "Confidence": 0.94389, "X1": 0.06928, "Y1": 0.6292, "X2": 0.45621, "Y2": 0.629, "X3": 0.45621, "Y3": 0.6428, "X4": 0.06928, "Y4": 0.6428, "page": 0}, {"Word": "mg of either proline or NPRO in 50 AL of water by the", "Confidence": 0.94415, "X1": 0.4915, "Y1": 0.6292, "X2": 0.88235, "Y2": 0.629, "X3": 0.88235, "Y3": 0.6438, "X4": 0.4915, "Y4": 0.6448, "page": 0}, {"Word": "Borgwaldt, Hamburg, FRG). Every second port of the", "Confidence": 0.95262, "X1": 0.06928, "Y1": 0.6422, "X2": 0.45882, "Y2": 0.642, "X3": 0.45882, "Y3": 0.6558, "X4": 0.06928, "Y4": 0.6558, "page": 0}, {"Word": "microsyringe technique (Hoffmann et al ., 1977).", "Confidence": 0.99257, "X1": 0.4902, "Y1": 0.6422, "X2": 0.82614, "Y2": 0.642, "X3": 0.82614, "Y3": 0.6558, "X4": 0.4902, "Y4": 0.6578, "page": 0}, {"Word": "smoking machine was connected to a nitrogen source which", "Confidence": 0.99422, "X1": 0.06928, "Y1": 0.6552, "X2": 0.45621, "Y2": 0.655, "X3": 0.45621, "Y3": 0.6688, "X4": 0.06928, "Y4": 0.6688, "page": 0}, {"Word": "Other Analytical Methods. For the analysis of VNA", "Confidence": 0.9935, "X1": 0.50065, "Y1": 0.6552, "X2": 0.88366, "Y2": 0.655, "X3": 0.88366, "Y3": 0.6698, "X4": 0.50065, "Y4": 0.6698, "page": 0}, {"Word": "replaced the air with nitrogen in order to prevent the", "Confidence": 0.9832, "X1": 0.06928, "Y1": 0.6682, "X2": 0.45882, "Y2": 0.668, "X3": 0.45882, "Y3": 0.6828, "X4": 0.06928, "Y4": 0.6818, "page": 0}, {"Word": "and TSNA in tobacco we employed earlier published", "Confidence": 0.98725, "X1": 0.49281, "Y1": 0.6692, "X2": 0.87974, "Y2": 0.669, "X3": 0.87974, "Y3": 0.6828, "X4": 0.49281, "Y4": 0.6828, "page": 0}, {"Word": "possible artifactual formation of nitrosamines in the", "Confidence": 0.95029, "X1": 0.06928, "Y1": 0.6812, "X2": 0.46013, "Y2": 0.681, "X3": 0.46013, "Y3": 0.6968, "X4": 0.06928, "Y4": 0.6958, "page": 0}, {"Word": "methods (Brunnemann et al ., 1977; Hoffmann et al, 1979).", "Confidence": 0.9906, "X1": 0.48889, "Y1": 0.6822, "X2": 0.87974, "Y2": 0.682, "X3": 0.87974, "Y3": 0.6958, "X4": 0.48889, "Y4": 0.6958, "page": 0}, {"Word": "headspace of the device and the trap (Hoffmann et al .,", "Confidence": 0.95664, "X1": 0.06797, "Y1": 0.6932, "X2": 0.45752, "Y2": 0.693, "X3": 0.45752, "Y3": 0.7068, "X4": 0.06797, "Y4": 0.7068, "page": 0}, {"Word": "For the determination of moisture in tobacco, a modified", "Confidence": 0.96722, "X1": 0.49281, "Y1": 0.6942, "X2": 0.88105, "Y2": 0.694, "X3": 0.88105, "Y3": 0.7078, "X4": 0.49281, "Y4": 0.7078, "page": 0}, {"Word": "1976).", "Confidence": 0.961, "X1": 0.06928, "Y1": 0.7062, "X2": 0.11503, "Y2": 0.706, "X3": 0.11373, "Y3": 0.7188, "X4": 0.06928, "Y4": 0.7188, "page": 0}, {"Word": "Dean-Stark procedure was used (von Bethmann et al .,", "Confidence": 0.89911, "X1": 0.4915, "Y1": 0.7062, "X2": 0.87974, "Y2": 0.706, "X3": 0.87974, "Y3": 0.7208, "X4": 0.4915, "Y4": 0.7208, "page": 0}, {"Word": "Determination of NPRO in Tobacco. Five grams of", "Confidence": 0.97137, "X1": 0.08235, "Y1": 0.7182, "X2": 0.45752, "Y2": 0.718, "X3": 0.45752, "Y3": 0.7338, "X4": 0.08235, "Y4": 0.7328, "page": 0}, {"Word": "1961). Nitrate in tobacco was determined by the specific", "Confidence": 0.98422, "X1": 0.4915, "Y1": 0.7202, "X2": 0.88235, "Y2": 0.72, "X3": 0.88235, "Y3": 0.7348, "X4": 0.4915, "Y4": 0.7338, "page": 0}, {"Word": "tobacco was extracted for 2 h withf.00 mL of water con-", "Confidence": 0.94664, "X1": 0.06928, "Y1": 0.7322, "X2": 0.45752, "Y2": 0.732, "X3": 0.45752, "Y3": 0.7468, "X4": 0.06928, "Y4": 0.7458, "page": 0}, {"Word": "ion electrode method (Jacin, 1970).", "Confidence": 0.9784, "X1": 0.49281, "Y1": 0.7332, "X2": 0.73725, "Y2": 0.733, "X3": 0.73725, "Y3": 0.7458, "X4": 0.49281, "Y4": 0.7468, "page": 0}, {"Word": "taining 6 mL of AS solution (20% ammonium sulfamate", "Confidence": 0.94911, "X1": 0.06928, "Y1": 0.7452, "X2": 0.45621, "Y2": 0.745, "X3": 0.45621, "Y3": 0.7578, "X4": 0.06928, "Y4": 0.7578, "page": 0}, {"Word": "Statistical Evaluations. Linear regression models", "Confidence": 0.917, "X1": 0.50458, "Y1": 0.7452, "X2": 0.88105, "Y2": 0.745, "X3": 0.88105, "Y3": 0.7598, "X4": 0.50458, "Y4": 0.7588, "page": 0}, {"Word": "in 3.6 N sulfuric acid) and NPRO-U-\"C (96 500 dpm/27", "Confidence": 0.9561, "X1": 0.06928, "Y1": 0.7572, "X2": 0.45621, "Y2": 0.757, "X3": 0.45621, "Y3": 0.7708, "X4": 0.06928, "Y4": 0.7698, "page": 0}, {"Word": "were calculated on an IBM 4341 Model Il mainframe by", "Confidence": 0.9507, "X1": 0.49412, "Y1": 0.7572, "X2": 0.88235, "Y2": 0.757, "X3": 0.88235, "Y3": 0.7718, "X4": 0.49412, "Y4": 0.7728, "page": 0}, {"Word": "ng) as an internal standard. Subsequently, the mixture", "Confidence": 0.97488, "X1": 0.07059, "Y1": 0.7702, "X2": 0.45752, "Y2": 0.77, "X3": 0.45752, "Y3": 0.7838, "X4": 0.07059, "Y4": 0.7838, "page": 0}, {"Word": "using a statistics analysis system (SAS Institute, Cary, NC).", "Confidence": 0.95289, "X1": 0.49412, "Y1": 0.7692, "X2": 0.88105, "Y2": 0.769, "X3": 0.88105, "Y3": 0.7838, "X4": 0.49412, "Y4": 0.7858, "page": 0}, {"Word": "was filtered through Celite 545. After the addition of 20", "Confidence": 0.9756, "X1": 0.06797, "Y1": 0.7832, "X2": 0.45882, "Y2": 0.783, "X3": 0.45882, "Y3": 0.7968, "X4": 0.06797, "Y4": 0.7968, "page": 0}, {"Word": "RESULTS AND DISCUSSION", "Confidence": 0.996, "X1": 0.49281, "Y1": 0.7902, "X2": 0.69673, "Y2": 0.79, "X3": 0.69673, "Y3": 0.8038, "X4": 0.49281, "Y4": 0.8048, "page": 0}, {"Word": "g of NaCl, the filtrate was partitioned with 4 x 150 mL", "Confidence": 0.93408, "X1": 0.06928, "Y1": 0.7952, "X2": 0.45882, "Y2": 0.795, "X3": 0.45882, "Y3": 0.8098, "X4": 0.06928, "Y4": 0.8098, "page": 0}, {"Word": "of ethyl acetate. The combined organic layers were dried", "Confidence": 0.948, "X1": 0.07059, "Y1": 0.8092, "X2": 0.45882, "Y2": 0.809, "X3": 0.45882, "Y3": 0.8228, "X4": 0.07059, "Y4": 0.8218, "page": 0}, {"Word": "Analysis of Tobacco for NPRO. A schematic repre-", "Confidence": 0.95138, "X1": 0.5085, "Y1": 0.8082, "X2": 0.88235, "Y2": 0.808, "X3": 0.88235, "Y3": 0.8228, "X4": 0.5085, "Y4": 0.8218, "page": 0}, {"Word": "(Na,SO) and reduced to 0.1 mL in a rotary evaporator.", "Confidence": 0.9215, "X1": 0.07059, "Y1": 0.8222, "X2": 0.45621, "Y2": 0.822, "X3": 0.45621, "Y3": 0.8368, "X4": 0.07059, "Y4": 0.8348, "page": 0}, {"Word": "sentation of the NPRO analysis in tobacco is shown in", "Confidence": 0.9951, "X1": 0.49281, "Y1": 0.8212, "X2": 0.88235, "Y2": 0.821, "X3": 0.88235, "Y3": 0.8348, "X4": 0.49281, "Y4": 0.8348, "page": 0}, {"Word": "One milliliter of 14% BF, in MeOH was added to the", "Confidence": 0.93955, "X1": 0.06928, "Y1": 0.8342, "X2": 0.45621, "Y2": 0.834, "X3": 0.45621, "Y3": 0.8478, "X4": 0.06928, "Y4": 0.8468, "page": 0}, {"Word": "Figure 1. It involves extraction, solvent partition, and", "Confidence": 0.99, "X1": 0.49412, "Y1": 0.8332, "X2": 0.88235, "Y2": 0.833, "X3": 0.88235, "Y3": 0.8478, "X4": 0.49412, "Y4": 0.8478, "page": 0}, {"Word": "residue and the mixture was heated att 60 \u2103 for 1 h. After", "Confidence": 0.82331, "X1": 0.06928, "Y1": 0.8482, "X2": 0.45882, "Y2": 0.848, "X3": 0.45882, "Y3": 0.8608, "X4": 0.06928, "Y4": 0.8598, "page": 0}, {"Word": "subsequent methylation as well as GC-TEA analysis.", "Confidence": 0.98757, "X1": 0.49281, "Y1": 0.8472, "X2": 0.88366, "Y2": 0.847, "X3": 0.88366, "Y3": 0.8608, "X4": 0.49281, "Y4": 0.8618, "page": 0}, {"Word": "the mixture was cooled to ambient temperature, 1 mL of", "Confidence": 0.9819, "X1": 0.07059, "Y1": 0.8602, "X2": 0.45752, "Y2": 0.86, "X3": 0.45752, "Y3": 0.8738, "X4": 0.07059, "Y4": 0.8728, "page": 0}, {"Word": "Figure 2 shows the GC-TEA trace of a concentrate from", "Confidence": 0.9945, "X1": 0.4915, "Y1": 0.8592, "X2": 0.88366, "Y2": 0.859, "X3": 0.88366, "Y3": 0.8738, "X4": 0.4915, "Y4": 0.8738, "page": 0}, {"Word": "dichloromethane and 4 mL of water were added. The", "Confidence": 0.98844, "X1": 0.06928, "Y1": 0.8732, "X2": 0.45882, "Y2": 0.873, "X3": 0.45882, "Y3": 0.8868, "X4": 0.06928, "Y4": 0.8858, "page": 0}, {"Word": "a cigarette tobacco extract depicting the methyl ester of", "Confidence": 0.99456, "X1": 0.49281, "Y1": 0.8722, "X2": 0.88105, "Y2": 0.872, "X3": 0.88105, "Y3": 0.8858, "X4": 0.49281, "Y4": 0.8868, "page": 0}, {"Word": "organic phase was removed and placed into a 1-mL serum", "Confidence": 0.9758, "X1": 0.06928, "Y1": 0.8852, "X2": 0.45752, "Y2": 0.885, "X3": 0.45752, "Y3": 0.8998, "X4": 0.06928, "Y4": 0.8998, "page": 0}, {"Word": "NPRO (retention time 5.5 min). In one case NPRO was", "Confidence": 0.981, "X1": 0.4915, "Y1": 0.8842, "X2": 0.88366, "Y2": 0.884, "X3": 0.88366, "Y3": 0.8988, "X4": 0.4915, "Y4": 0.8988, "page": 0}, {"Word": "vial together with 100 mg of Na,SO ,. An aliquot was used", "Confidence": 0.89742, "X1": 0.0719, "Y1": 0.8982, "X2": 0.46013, "Y2": 0.898, "X3": 0.46013, "Y3": 0.9128, "X4": 0.0719, "Y4": 0.9128, "page": 0}, {"Word": "enriched from 100 g of snuff tobacco following the ana-", "Confidence": 0.9791, "X1": 0.4902, "Y1": 0.8982, "X2": 0.88105, "Y2": 0.898, "X3": 0.88105, "Y3": 0.9118, "X4": 0.4902, "Y4": 0.9118, "page": 0}, {"Word": "to determine the recovery rate by scintillation counting.", "Confidence": 0.90275, "X1": 0.06928, "Y1": 0.9122, "X2": 0.45882, "Y2": 0.912, "X3": 0.45882, "Y3": 0.9268, "X4": 0.06928, "Y4": 0.9258, "page": 0}, {"Word": "lytical scheme (Figure 1) with an additional column", "Confidence": 0.97887, "X1": 0.4902, "Y1": 0.9112, "X2": 0.87974, "Y2": 0.911, "X3": 0.87974, "Y3": 0.9258, "X4": 0.4902, "Y4": 0.9268, "page": 0}, {"Word": "and a second aliquot was analyzed by GC-TEA on a 6 ft", "Confidence": 0.97708, "X1": 0.06797, "Y1": 0.9242, "X2": 0.46013, "Y2": 0.924, "X3": 0.46013, "Y3": 0.9388, "X4": 0.06797, "Y4": 0.9398, "page": 0}, {"Word": "chromatographic step and preparative TLC; NPRO was", "Confidence": 0.90929, "X1": 0.49281, "Y1": 0.9242, "X2": 0.88235, "Y2": 0.924, "X3": 0.88235, "Y3": 0.9388, "X4": 0.49412, "Y4": 0.9398, "page": 0}, {"Word": "2021652343", "Confidence": 0.961, "X1": 0.9281, "Y1": 0.9412, "X2": 0.93464, "Y2": 0.941, "X3": 0.90458, "Y3": 0.9418, "X4": 0.89804, "Y4": 0.7948, "page": 0}], "words_data": [{"Word": "Brunnemann,", "Confidence": 0.873, "X1": 0.67843, "Y1": 0.0152, "X2": 0.75294, "Y2": 0.015, "X3": 0.75294, "Y3": 0.0268, "X4": 0.67712, "Y4": 0.0268, "page": 0, "Index": 0}, {"Word": "Scott,", "Confidence": 0.911, "X1": 0.75686, "Y1": 0.0152, "X2": 0.79085, "Y2": 0.015, "X3": 0.79085, "Y3": 0.0268, "X4": 0.75556, "Y4": 0.0268, "page": 0, "Index": 1}, {"Word": "and", "Confidence": 0.998, "X1": 0.79477, "Y1": 0.0152, "X2": 0.81569, "Y2": 0.015, "X3": 0.81438, "Y3": 0.0278, "X4": 0.79346, "Y4": 0.0268, "page": 0, "Index": 2}, {"Word": "Hoffmann", "Confidence": 0.915, "X1": 0.8183, "Y1": 0.0152, "X2": 0.87843, "Y2": 0.015, "X3": 0.87843, "Y3": 0.0278, "X4": 0.8183, "Y4": 0.0278, "page": 0, "Index": 3}, {"Word": "906", "Confidence": 0.747, "X1": 0.06405, "Y1": 0.0152, "X2": 0.0902, "Y2": 0.015, "X3": 0.0902, "Y3": 0.0298, "X4": 0.06405, "Y4": 0.0298, "page": 0, "Index": 4}, {"Word": "J.", "Confidence": 0.703, "X1": 0.09935, "Y1": 0.0152, "X2": 0.11111, "Y2": 0.015, "X3": 0.11111, "Y3": 0.0298, "X4": 0.09935, "Y4": 0.0298, "page": 0, "Index": 5}, {"Word": "Agric.", "Confidence": 0.758, "X1": 0.11503, "Y1": 0.0152, "X2": 0.15033, "Y2": 0.015, "X3": 0.15033, "Y3": 0.0298, "X4": 0.11503, "Y4": 0.0298, "page": 0, "Index": 6}, {"Word": "Food", "Confidence": 0.989, "X1": 0.15425, "Y1": 0.0152, "X2": 0.18301, "Y2": 0.015, "X3": 0.18301, "Y3": 0.0298, "X4": 0.15425, "Y4": 0.0298, "page": 0, "Index": 7}, {"Word": "Chem", "Confidence": 0.929, "X1": 0.18693, "Y1": 0.0152, "X2": 0.21176, "Y2": 0.015, "X3": 0.21176, "Y3": 0.0298, "X4": 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Based on dry tobacco weight. Abbreviations: NNN = N'-nitrosonornicotine; TSNA - tobacco-specific N-nitrosamines;", "Confidence": 0.81707, "X1": 0.07068, "Y1": 0.2942, "X2": 0.86257, "Y2": 0.294, "X3": 0.86257, "Y3": 0.3068, "X4": 0.07068, "Y4": 0.3058, "page": 0}, {"Word": "PRO= proline; NPRO = N-nitrosoproline, \u00b7 Numbers indicate length in millimeters of cigarettes; E'= filter; NF = nonfilter.", "Confidence": 0.80311, "X1": 0.06152, "Y1": 0.3052, "X2": 0.86911, "Y2": 0.305, "X3": 0.86911, "Y3": 0.3178, "X4": 0.06152, "Y4": 0.3168, "page": 0}, {"Word": "Percent N-nitrosation of nicotine to NNN. \u00aa Percent N-nitrosation of PRO to NPRO.", "Confidence": 0.82823, "X1": 0.06283, "Y1": 0.3172, "X2": 0.63613, "Y2": 0.317, "X3": 0.63482, "Y3": 0.3288, "X4": 0.06283, "Y4": 0.3278, "page": 0}, {"Word": "extract 1 hour", "Confidence": 0.25667, "X1": 0.19764, "Y1": 0.3802, "X2": 0.25393, "Y2": 0.38, "X3": 0.25393, "Y3": 0.3878, "X4": 0.19764, "Y4": 0.3888, "page": 0}, {"Word": "TEA \u0130RESPONSE (R - 15)", "Confidence": 0.8036, "X1": 0.60733, "Y1": 0.4002, "X2": 0.60864, "Y2": 0.4, "X3": 0.62827, "Y3": 0.3998, "X4": 0.62435, "Y4": 0.4858, "page": 0}, {"Word": "Acard", "Confidence": 0.172, "X1": 0.12696, "Y1": 0.4462, "X2": 0.15576, "Y2": 0.446, "X3": 0.15707, "Y3": 0.4528, "X4": 0.12696, "Y4": 0.4538, "page": 0}, {"Word": "DOM layer", "Confidence": 0.5925, "X1": 0.19241, "Y1": 0.5082, "X2": 0.23691, "Y2": 0.508, "X3": 0.23691, "Y3": 0.5168, "X4": 0.19241, "Y4": 0.5158, "page": 0}, {"Word": "a layer", "Confidence": 0.3085, "X1": 0.35079, "Y1": 0.5092, "X2": 0.38089, "Y2": 0.509, "X3": 0.3822, "Y3": 0.5178, "X4": 0.3534, "Y4": 0.5178, "page": 0}, {"Word": "--", "Confidence": 0.476, "X1": 0.6911, "Y1": 0.5492, "X2": 0.6911, "Y2": 0.549, "X3": 0.68063, "Y3": 0.5508, "X4": 0.67932, "Y4": 0.5398, "page": 0}, {"Word": "MINUTES", "Confidence": 0.776, "X1": 0.66492, "Y1": 0.5512, "X2": 0.71073, "Y2": 0.551, "X3": 0.71073, "Y3": 0.5608, "X4": 0.66492, "Y4": 0.5618, "page": 0}, {"Word": "Figure 2. GC-TEA trace of cigarette tobacco extract (U.S ., F.", "Confidence": 0.83445, "X1": 0.48298, "Y1": 0.5612, "X2": 0.87435, "Y2": 0.561, "X3": 0.87435, "Y3": 0.5768, "X4": 0.48298, "Y4": 0.5768, "page": 0}, {"Word": "CC . TEA", "Confidence": 0.48833, "X1": 0.19503, "Y1": 0.5722, "X2": 0.2356, "Y2": 0.572, "X3": 0.2356, "Y3": 0.5808, "X4": 0.19503, "Y4": 0.5808, "page": 0}, {"Word": "85 mm, Ultra Light) showing the presence of NPRO.", "Confidence": 0.91033, "X1": 0.48429, "Y1": 0.5742, "X2": 0.81806, "Y2": 0.574, "X3": 0.81806, "Y3": 0.5868, "X4": 0.48429, "Y4": 0.5878, "page": 0}, {"Word": "10% DW - 20 M", "Confidence": 0.4848, "X1": 0.18194, "Y1": 0.5952, "X2": 0.24738, "Y2": 0.595, "X3": 0.24738, "Y3": 0.6018, "X4": 0.18194, "Y4": 0.6018, "page": 0}, {"Word": "Figure 1. Schematic for the analysis of NPRO.", "Confidence": 0.90125, "X1": 0.06545, "Y1": 0.6062, "X2": 0.37173, "Y2": 0.606, "X3": 0.37173, "Y3": 0.6208, "X4": 0.06545, "Y4": 0.6218, "page": 0}, {"Word": "then identified as the methyl ester by capillary GC-MS", "Confidence": 0.99167, "X1": 0.06545, "Y1": 0.6292, "X2": 0.45419, "Y2": 0.629, "X3": 0.45419, "Y3": 0.6458, "X4": 0.06545, "Y4": 0.6458, "page": 0}, {"Word": "RELATIVE ABUNDANCE (W)", "Confidence": 0.66467, "X1": 0.54843, "Y1": 0.6492, "X2": 0.54712, "Y2": 0.649, "X3": 0.56283, "Y3": 0.6488, "X4": 0.56414, "Y4": 0.7508, "page": 0}, {"Word": "(Figure 3).", "Confidence": 0.993, "X1": 0.06675, "Y1": 0.6442, "X2": 0.14529, "Y2": 0.644, "X3": 0.14529, "Y3": 0.6588, "X4": 0.06675, "Y4": 0.6578, "page": 0}, {"Word": "The identity of NPRO isolated from each tobacco sam-", "Confidence": 0.94722, "X1": 0.0733, "Y1": 0.6562, "X2": 0.45026, "Y2": 0.656, "X3": 0.45026, "Y3": 0.6708, "X4": 0.0733, "Y4": 0.6698, "page": 0}, {"Word": "ple was assured by established , confirmatory methods", "Confidence": 0.86238, "X1": 0.06545, "Y1": 0.6702, "X2": 0.45419, "Y2": 0.67, "X3": 0.45419, "Y3": 0.6848, "X4": 0.06545, "Y4": 0.6838, "page": 0}, {"Word": "(Krull et at ., 1979). When both the standard solution of", "Confidence": 0.98036, "X1": 0.06545, "Y1": 0.6832, "X2": 0.45288, "Y2": 0.683, "X3": 0.45288, "Y3": 0.6968, "X4": 0.06545, "Y4": 0.6968, "page": 0}, {"Word": "80 100 120 1491", "Confidence": 0.84325, "X1": 0.67539, "Y1": 0.6822, "X2": 0.79188, "Y2": 0.682, "X3": 0.79188, "Y3": 0.6928, "X4": 0.67539, "Y4": 0.6928, "page": 0}, {"Word": "NPRO and the concentrates from the tobacco extracts", "Confidence": 0.95825, "X1": 0.06545, "Y1": 0.6962, "X2": 0.45157, "Y2": 0.696, "X3": 0.45157, "Y3": 0.7098, "X4": 0.06545, "Y4": 0.7088, "page": 0}, {"Word": "ISOLATED FROM SHUFF TOBACCO", "Confidence": 0.3385, "X1": 0.61387, "Y1": 0.7012, "X2": 0.7644, "Y2": 0.701, "X3": 0.7644, "Y3": 0.7128, "X4": 0.61387, "Y4": 0.7128, "page": 0}, {"Word": "were treated with HBr, the NPRO peak in the GC-TEA", "Confidence": 0.9839, "X1": 0.06283, "Y1": 0.7082, "X2": 0.44895, "Y2": 0.708, "X3": 0.44895, "Y3": 0.7218, "X4": 0.06283, "Y4": 0.7228, "page": 0}, {"Word": "disappeared completely. For a more positive confirmation", "Confidence": 0.98257, "X1": 0.06283, "Y1": 0.7212, "X2": 0.45026, "Y2": 0.721, "X3": 0.45026, "Y3": 0.7368, "X4": 0.06283, "Y4": 0.7358, "page": 0}, {"Word": "we oxidized NPRO to the corresponding nitramine", "Confidence": 0.96357, "X1": 0.06545, "Y1": 0.7352, "X2": 0.44895, "Y2": 0.735, "X3": 0.44895, "Y3": 0.7488, "X4": 0.06545, "Y4": 0.7478, "page": 0}, {"Word": "[C.H,(COOH)N-NO-C,H, (@00H)N-NO_] using the", "Confidence": 0.66475, "X1": 0.06414, "Y1": 0.7472, "X2": 0.45157, "Y2": 0.747, "X3": 0.45157, "Y3": 0.7618, "X4": 0.06414, "Y4": 0.7608, "page": 0}, {"Word": "method of Emmons (1957) modi ed to include acetic an-", "Confidence": 0.953, "X1": 0.06414, "Y1": 0.7612, "X2": 0.45419, "Y2": 0.761, "X3": 0.45419, "Y3": 0.7738, "X4": 0.06414, "Y4": 0.7728, "page": 0}, {"Word": "hydride and 50% hydrogen peroxide in place of tri-", "Confidence": 0.95144, "X1": 0.06675, "Y1": 0.7722, "X2": 0.45026, "Y2": 0.772, "X3": 0.45026, "Y3": 0.7868, "X4": 0.06675, "Y4": 0.7868, "page": 0}, {"Word": "120 1", "Confidence": 0.9885, "X1": 0.72382, "Y1": 0.7702, "X2": 0.76832, "Y2": 0.77, "X3": 0.76832, "Y3": 0.7798, "X4": 0.72382, "Y4": 0.7808, "page": 0}, {"Word": "180", "Confidence": 0.772, "X1": 0.78403, "Y1": 0.7692, "X2": 0.8089, "Y2": 0.769, "X3": 0.8089, "Y3": 0.7798, "X4": 0.78403, "Y4": 0.7788, "page": 0}, {"Word": "fluoroacetic acid anhydride and 90% H,O, (Sen et al .,", "Confidence": 0.829, "X1": 0.06545, "Y1": 0.7862, "X2": 0.45157, "Y2": 0.786, "X3": 0.45157, "Y3": 0.7998, "X4": 0.06545, "Y4": 0.7988, "page": 0}, {"Word": "1982). (This treatment had to precede the methylation", "Confidence": 0.96363, "X1": 0.06414, "Y1": 0.7992, "X2": 0.44895, "Y2": 0.799, "X3": 0.44895, "Y3": 0.8128, "X4": 0.06414, "Y4": 0.8118, "page": 0}, {"Word": "Figure 3. Mam spectra of reference and isolate from snuff tobacco", "Confidence": 0.81018, "X1": 0.4856, "Y1": 0.7992, "X2": 0.87565, "Y2": 0.799, "X3": 0.87565, "Y3": 0.8118, "X4": 0.4856, "Y4": 0.8118, "page": 0}, {"Word": "in order to avoid hydrolysis of the methyl ester of NPRO", "Confidence": 0.96018, "X1": 0.06545, "Y1": 0.8112, "X2": 0.45288, "Y2": 0.811, "X3": 0.45288, "Y3": 0.8248, "X4": 0.06545, "Y4": 0.8258, "page": 0}, {"Word": "showing NPRO as the methyl ester.", "Confidence": 0.86433, "X1": 0.48691, "Y1": 0.8122, "X2": 0.71335, "Y2": 0.812, "X3": 0.71335, "Y3": 0.8238, "X4": 0.48691, "Y4": 0.8248, "page": 0}, {"Word": "prior to GC-TEA analysis.) A NPRO standard solution", "Confidence": 0.96413, "X1": 0.06414, "Y1": 0.8242, "X2": 0.45157, "Y2": 0.824, "X3": 0.45157, "Y3": 0.8378, "X4": 0.06414, "Y4": 0.8378, "page": 0}, {"Word": "treated with BF ,- MeOH showed that approximately half", "Confidence": 0.90189, "X1": 0.06545, "Y1": 0.8372, "X2": 0.45288, "Y2": 0.837, "X3": 0.45157, "Y3": 0.8508, "X4": 0.06545, "Y4": 0.8498, "page": 0}, {"Word": "termined as the methyl ester. When we started with 5 g", "Confidence": 0.98064, "X1": 0.4856, "Y1": 0.8362, "X2": 0.87565, "Y2": 0.836, "X3": 0.87565, "Y3": 0.8498, "X4": 0.4856, "Y4": 0.8508, "page": 0}, {"Word": "of the NPRO was oxidized to the 'corresponding nitramine", "Confidence": 0.95078, "X1": 0.06675, "Y1": 0.8502, "X2": 0.45026, "Y2": 0.85, "X3": 0.45026, "Y3": 0.8638, "X4": 0.06675, "Y4": 0.8628, "page": 0}, {"Word": "of processed tobacco, the detection limit was about 0.2", "Confidence": 0.956, "X1": 0.48822, "Y1": 0.8482, "X2": 0.87565, "Y2": 0.848, "X3": 0.87565, "Y3": 0.8618, "X4": 0.48822, "Y4": 0.8638, "page": 0}, {"Word": "as detected by GC-TEA at a TEA pyrolyzer temperature", "Confidence": 0.91556, "X1": 0.06545, "Y1": 0.8622, "X2": 0.45026, "Y2": 0.862, "X3": 0.45026, "Y3": 0.8758, "X4": 0.06545, "Y4": 0.8748, "page": 0}, {"Word": "ng/g.", "Confidence": 0.614, "X1": 0.48822, "Y1": 0.8642, "X2": 0.52618, "Y2": 0.864, "X3": 0.52618, "Y3": 0.8768, "X4": 0.48822, "Y4": 0.8748, "page": 0}, {"Word": "of 800 \u2103. The retention time of the methylated nitramine", "Confidence": 0.9498, "X1": 0.06675, "Y1": 0.8752, "X2": 0.45288, "Y2": 0.875, "X3": 0.45288, "Y3": 0.8878, "X4": 0.06675, "Y4": 0.8878, "page": 0}, {"Word": "When using 25 g of green leaves (nitrate content 0.2%)", "Confidence": 0.9839, "X1": 0.49607, "Y1": 0.8732, "X2": 0.87565, "Y2": 0.873, "X3": 0.87565, "Y3": 0.8878, "X4": 0.49607, "Y4": 0.8898, "page": 0}, {"Word": "was exactly twice that of the methyl ester of NPRO.", "Confidence": 0.9822, "X1": 0.06675, "Y1": 0.8872, "X2": 0.42801, "Y2": 0.887, "X3": 0.42801, "Y3": 0.9008, "X4": 0.06675, "Y4": 0.9018, "page": 0}, {"Word": "which was analyzed immediately after removal from the", "Confidence": 0.96525, "X1": 0.48691, "Y1": 0.8862, "X2": 0.87565, "Y2": 0.886, "X3": 0.87565, "Y3": 0.9008, "X4": 0.48691, "Y4": 0.9018, "page": 0}, {"Word": "On the basis of five analyses of the Kentucky reference", "Confidence": 0.9755, "X1": 0.07723, "Y1": 0.9012, "X2": 0.45026, "Y2": 0.901, "X3": 0.45026, "Y3": 0.9148, "X4": 0.07723, "Y4": 0.9138, "page": 0}, {"Word": "stalk of a Burley 21 tobacco plant, we were unable to detect", "Confidence": 0.97775, "X1": 0.4856, "Y1": 0.8992, "X2": 0.87565, "Y2": 0.899, "X3": 0.87565, "Y3": 0.9138, "X4": 0.4856, "Y4": 0.9148, "page": 0}, {"Word": "cigarette, the relative standard deviation for NPRO and", "Confidence": 0.983, "X1": 0.06806, "Y1": 0.9142, "X2": 0.45026, "Y2": 0.914, "X3": 0.45026, "Y3": 0.9298, "X4": 0.06806, "Y4": 0.9308, "page": 0}, {"Word": "measurable amounts of NPRO (<5 ppb). This result", "Confidence": 0.94025, "X1": 0.4856, "Y1": 0.9132, "X2": 0.87435, "Y2": 0.913, "X3": 0.87565, "Y3": 0.9288, "X4": 0.4856, "Y4": 0.9298, "page": 0}, {"Word": "PRO was +8%. According to the loss of the \"C-labeled", "Confidence": 0.9326, "X1": 0.06675, "Y1": 0.9272, "X2": 0.45026, "Y2": 0.927, "X3": 0.45026, "Y3": 0.9418, "X4": 0.06675, "Y4": 0.9408, "page": 0}, {"Word": "supports our earlier observation (Hecht et al, 1978; Adams", "Confidence": 0.95022, "X1": 0.4856, "Y1": 0.9272, "X2": 0.87435, "Y2": 0.927, "X3": 0.87435, "Y3": 0.9418, "X4": 0.4856, "Y4": 0.9428, "page": 0}, {"Word": "internal standard, 65-75% of NPRO and proline were", "Confidence": 0.98438, "X1": 0.06545, "Y1": 0.9412, "X2": 0.45157, "Y2": 0.941, "X3": 0.45157, "Y3": 0.9558, "X4": 0.06545, "Y4": 0.9558, "page": 0}, {"Word": "et al ., 1983) that N-nitrosamines are primarily formed", "Confidence": 0.94256, "X1": 0.48691, "Y1": 0.9412, "X2": 0.87304, "Y2": 0.941, "X3": 0.87173, "Y3": 0.9558, "X4": 0.48691, "Y4": 0.9558, "page": 0}, {"Word": "2021652344", "Confidence": 0.995, "X1": 0.90969, "Y1": 0.9532, "X2": 0.91885, "Y2": 0.953, "X3": 0.88743, "Y3": 0.9538, "X4": 0.88089, "Y4": 0.8018, "page": 0}, {"Word": "enriched in the concentrate from which NPRO was de-", "Confidence": 0.99389, "X1": 0.06675, "Y1": 0.9542, "X2": 0.45288, "Y2": 0.954, "X3": 0.45288, "Y3": 0.9678, "X4": 0.06675, "Y4": 0.9688, "page": 0}, {"Word": "during tobacco processing.", "Confidence": 0.982, "X1": 0.4856, "Y1": 0.9562, "X2": 0.67408, "Y2": 0.956, "X3": 0.67408, "Y3": 0.9708, "X4": 0.4856, "Y4": 0.9688, "page": 0}], "words_data": [{"Word": "N-Nitrosoproline", "Confidence": 0.664, "X1": 0.06545, "Y1": 0.0452, "X2": 0.15576, "Y2": 0.045, "X3": 0.15576, "Y3": 0.0578, "X4": 0.06414, "Y4": 0.0578, "page": 0, "Index": 0}, {"Word": "as", "Confidence": 0.997, "X1": 0.15969, "Y1": 0.0452, "X2": 0.17408, "Y2": 0.045, "X3": 0.17277, "Y3": 0.0578, "X4": 0.15838, "Y4": 0.0578, "page": 0, "Index": 1}, {"Word": "an", "Confidence": 0.997, "X1": 0.1767, "Y1": 0.0452, "X2": 0.19241, "Y2": 0.045, "X3": 0.19241, "Y3": 0.0578, "X4": 0.1767, "Y4": 0.0578, "page": 0, "Index": 2}, {"Word": "Indicator", "Confidence": 0.948, "X1": 0.19634, "Y1": 0.0452, "X2": 0.24869, "Y2": 0.045, "X3": 0.24738, "Y3": 0.0578, "X4": 0.19503, "Y4": 0.0578, "page": 0, "Index": 3}, {"Word": "for", "Confidence": 0.955, "X1": 0.25131, "Y1": 0.0452, "X2": 0.26963, "Y2": 0.045, "X3": 0.26832, "Y3": 0.0578, "X4": 0.25131, "Y4": 0.0578, "page": 0, "Index": 4}, {"Word": "Amine", "Confidence": 0.632, "X1": 0.27225, "Y1": 0.0452, "X2": 0.31021, "Y2": 0.045, "X3": 0.3089, "Y3": 0.0578, "X4": 0.27225, "Y4": 0.0578, "page": 0, "Index": 5}, {"Word": "N-Nitrosation", "Confidence": 0.942, "X1": 0.31283, "Y1": 0.0442, "X2": 0.39005, "Y2": 0.044, "X3": 0.39005, "Y3": 0.0578, "X4": 0.31283, "Y4": 0.0578, "page": 0, "Index": 6}, {"Word": "J.", "Confidence": 0.997, "X1": 0.58901, "Y1": 0.0432, "X2": 0.59817, "Y2": 0.043, "X3": 0.59817, "Y3": 0.0578, "X4": 0.5877, "Y4": 0.0578, "page": 0, "Index": 7}, {"Word": "Agric.", "Confidence": 0.662, "X1": 0.60209, "Y1": 0.0442, "X2": 0.63613, "Y2": 0.044, "X3": 0.63482, "Y3": 0.0578, "X4": 0.60079, 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S .; Haley, N. J .; Brunnemann, K. D .;", "Confidence": 0.93053, "X1": 0.49607, "Y1": 0.1672, "X2": 0.88613, "Y2": 0.167, "X3": 0.88482, "Y3": 0.1808, "X4": 0.49476, "Y4": 0.1788, "page": 0}, {"Word": "\u00aa 85-mm nonfilter cigarette; 0.70% NO ,, 990 ppm of", "Confidence": 0.8348, "X1": 0.07984, "Y1": 0.1832, "X2": 0.42801, "Y2": 0.183, "X3": 0.42801, "Y3": 0.1948, "X4": 0.07984, "Y4": 0.1938, "page": 0}, {"Word": "Adams, J. D .; Wynder, E. L. \"Human Carcinogenesis\"; Harris,", "Confidence": 0.8728, "X1": 0.50916, "Y1": 0.1802, "X2": 0.88482, "Y2": 0.18, "X3": 0.88482, "Y3": 0.1928, "X4": 0.50916, "Y4": 0.1908, "page": 0}, {"Word": "PRO, 0.88 ppm of NPRO. \u00ba n.d. = not detected (detec-", "Confidence": 0.88491, "X1": 0.06937, "Y1": 0.1942, "X2": 0.43717, "Y2": 0.194, "X3": 0.43717, "Y3": 0.2068, "X4": 0.06937, "Y4": 0.2048, "page": 0}, {"Word": "C. C .; Autrup, H ., Eds .; Academic Press: New York, 1983; in", "Confidence": 0.877, "X1": 0.51047, "Y1": 0.1912, "X2": 0.8822, "Y2": 0.191, "X3": 0.8822, "Y3": 0.2048, "X4": 0.51047, "Y4": 0.2038, "page": 0}, {"Word": "tion limit 0.5 ng/cigarette). \u20ac Approximately 1 ng/", "Confidence": 0.86037, "X1": 0.07068, "Y1": 0.2072, "X2": 0.40838, "Y2": 0.207, "X3": 0.40838, "Y3": 0.2178, "X4": 0.07068, "Y4": 0.2168, "page": 0}, {"Word": "press.", "Confidence": 0.659, "X1": 0.50785, "Y1": 0.2042, "X2": 0.54974, "Y2": 0.204, "X3": 0.54974, "Y3": 0.2158, "X4": 0.50785, "Y4": 0.2148, "page": 0}, {"Word": "cigarette. @ 0.073% by decarboxylation. \"Abbreviations:", "Confidence": 0.75917, "X1": 0.07068, "Y1": 0.2182, "X2": 0.45419, "Y2": 0.218, "X3": 0.45419, "Y3": 0.2298, "X4": 0.07068, "Y4": 0.2278, "page": 0}, {"Word": "Hoffmann, D .; Hecht, S. S .; Schmeltz, I .; Brunnemann, K. D .;", "Confidence": 0.82779, "X1": 0.49215, "Y1": 0.2162, "X2": 0.88482, "Y2": 0.216, "X3": 0.88482, "Y3": 0.2288, "X4": 0.49215, "Y4": 0.2278, "page": 0}, {"Word": "see footnote a of Tables I and IL", "Confidence": 0.9125, "X1": 0.07068, "Y1": 0.2282, "X2": 0.28534, "Y2": 0.228, "X3": 0.28534, "Y3": 0.2398, "X4": 0.07068, "Y4": 0.2398, "page": 0}, {"Word": "Wynder, E. L. Recent Adu. Tob. Sci. 1976, 1, 97.", "Confidence": 0.904, "X1": 0.50654, "Y1": 0.2272, "X2": 0.81675, "Y2": 0.227, "X3": 0.81675, "Y3": 0.2398, "X4": 0.50654, "Y4": 0.2398, "page": 0}, {"Word": "International Agency for Research on Cancer IARC Monogr. Eual.", "Confidence": 0.88233, "X1": 0.49215, "Y1": 0.2392, "X2": 0.8822, "Y2": 0.239, "X3": 0.8822, "Y3": 0.2528, "X4": 0.49215, "Y4": 0.2518, "page": 0}, {"Word": "one may conclude that if cigarette smoke contains any", "Confidence": 0.98656, "X1": 0.06937, "Y1": 0.2532, "X2": 0.45812, "Y2": 0.253, "X3": 0.45812, "Y3": 0.2678, "X4": 0.06937, "Y4": 0.2658, "page": 0}, {"Word": "Carcinog. Risk Chem. Hum. 1978, 17, 303.", "Confidence": 0.949, "X1": 0.50785, "Y1": 0.2512, "X2": 0.77487, "Y2": 0.251, "X3": 0.77487, "Y3": 0.2638, "X4": 0.50785, "Y4": 0.2628, "page": 0}, {"Word": "Jacin, H. Tobacco Sci. 1970, 14, 28.", "Confidence": 0.96829, "X1": 0.49476, "Y1": 0.2632, "X2": 0.71728, "Y2": 0.263, "X3": 0.71728, "Y3": 0.2748, "X4": 0.49476, "Y4": 0.2748, "page": 0}, {"Word": "NPRO, it is less than 1.0 ng/cigarette.", "Confidence": 0.99, "X1": 0.07199, "Y1": 0.2672, "X2": 0.34162, "Y2": 0.267, "X3": 0.34162, "Y3": 0.2808, "X4": 0.07199, "Y4": 0.2778, "page": 0}, {"Word": "ACKNOWLEDGMENT", "Confidence": 0.992, "X1": 0.07199, "Y1": 0.2832, "X2": 0.22644, "Y2": 0.283, "X3": 0.22644, "Y3": 0.2958, "X4": 0.07199, "Y4": 0.2948, "page": 0}, {"Word": "Krull, I. S .; Goff, E. U .; Hoffman, G. G .; Fine, D. H. Anal. Chem.", "Confidence": 0.92494, "X1": 0.49476, "Y1": 0.2752, "X2": 0.88351, "Y2": 0.275, "X3": 0.88351, "Y3": 0.2888, "X4": 0.49476, "Y4": 0.2868, "page": 0}, {"Word": "1979. 57, 1706.", "Confidence": 0.73467, "X1": 0.50654, "Y1": 0.2872, "X2": 0.60209, "Y2": 0.287, "X3": 0.60209, "Y3": 0.2988, "X4": 0.50654, "Y4": 0.2978, "page": 0}, {"Word": "We thank Dr. T. C. Tso from the U.S. Department of", "Confidence": 0.97645, "X1": 0.08508, "Y1": 0.3002, "X2": 0.46204, "Y2": 0.3, "X3": 0.46073, "Y3": 0.3138, "X4": 0.08508, "Y4": 0.3118, "page": 0}, {"Word": "Lijinsky, W .; Keefer, L; Lao, J. Tetrahedron Lett. 1970, 26, 5137 .-", "Confidence": 0.76646, "X1": 0.49476, "Y1": 0.2982, "X2": 0.88743, "Y2": 0.298, "X3": 0.88743, "Y3": 0.3118, "X4": 0.49476, "Y4": 0.3108, "page": 0}, {"Word": "Agriculture, Beltsville, MD, for supplying Burley-21 to-", "Confidence": 0.98886, "X1": 0.06937, "Y1": 0.3132, "X2": 0.45681, "Y2": 0.313, "X3": 0.45681, "Y3": 0.3278, "X4": 0.06937, "Y4": 0.3268, "page": 0}, {"Word": "Obshima, H .; Bartach, H. Cancer Res. 1981, 41, 3658.", "Confidence": 0.8551, "X1": 0.49346, "Y1": 0.3112, "X2": 0.82984, "Y2": 0.311, "X3": 0.82984, "Y3": 0.3238, "X4": 0.49346, "Y4": 0.3228, "page": 0}, {"Word": "Sen, N. P .; Seaman, S .; Tessier, L. JARC Sci. Publ. 1982, 41, 185.", "Confidence": 0.85427, "X1": 0.49346, "Y1": 0.3222, "X2": 0.88089, "Y2": 0.322, "X3": 0.88089, "Y3": 0.3358, "X4": 0.49346, "Y4": 0.3348, "page": 0}, {"Word": "bacco planta and S. Adams and J. Hambel for their ex-", "Confidence": 0.94755, "X1": 0.06937, "Y1": 0.3262, "X2": 0.45812, "Y2": 0.326, "X3": 0.45812, "Y3": 0.3398, "X4": 0.06937, "Y4": 0.3388, "page": 0}, {"Word": "U.S. Surgeon General \"The Health Consequences of Smoking", "Confidence": 0.918, "X1": 0.48953, "Y1": 0.3352, "X2": 0.88351, "Y2": 0.335, "X3": 0.8822, "Y3": 0.3478, "X4": 0.48953, "Y4": 0.3458, "page": 0}, {"Word": "cellent technical support.", "Confidence": 0.956, "X1": 0.06937, "Y1": 0.3402, "X2": 0.24738, "Y2": 0.34, "X3": 0.24738, "Y3": 0.3538, "X4": 0.06806, "Y4": 0.3518, "page": 0}, {"Word": "Cancer\", U.S. Surgeon General: Washington, DC, 1982; DHHS", "Confidence": 0.90337, "X1": 0.50262, "Y1": 0.3472, "X2": 0.8822, "Y2": 0.347, "X3": 0.88089, "Y3": 0.3598, "X4": 0.50262, "Y4": 0.3578, "page": 0}, {"Word": "Registry No. NPRO, 7519-36-0; N-nitrosopyrrolidine, 930-", "Confidence": 0.92917, "X1": 0.08246, "Y1": 0.3562, "X2": 0.45681, "Y2": 0.356, "X3": 0.45681, "Y3": 0.3688, "X4": 0.08246, "Y4": 0.3678, "page": 0}, {"Word": "(PHS) 82-50179, pp 181-235.", "Confidence": 0.97175, "X1": 0.50785, "Y1": 0.3582, "X2": 0.69372, "Y2": 0.358, "X3": 0.69372, "Y3": 0.3708, "X4": 0.50785, "Y4": 0.3688, "page": 0}, {"Word": "55-2; N'-nitrosonornicotine, 16543-55-8.", "Confidence": 0.513, "X1": 0.07199, "Y1": 0.3682, "X2": 0.31937, "Y2": 0.368, "X3": 0.31806, "Y3": 0.3808, "X4": 0.07199, "Y4": 0.3788, "page": 0}, {"Word": "von Bethmann, M .; Lipp, G; Van Nooy, H. Beitr. Tabakforsch.", "Confidence": 0.81836, "X1": 0.49346, "Y1": 0.3692, "X2": 0.88351, "Y2": 0.369, "X3": 0.88351, "Y3": 0.3838, "X4": 0.49346, "Y4": 0.3828, "page": 0}, {"Word": "LITERATURE CITED", "Confidence": 0.9945, "X1": 0.07068, "Y1": 0.3832, "X2": 0.22251, "Y2": 0.383, "X3": 0.22251, "Y3": 0.3978, "X4": 0.07068, "Y4": 0.3968, "page": 0}, {"Word": "1961, 2, 19.", "Confidence": 0.94233, "X1": 0.51047, "Y1": 0.3812, "X2": 0.58115, "Y2": 0.381, "X3": 0.58115, "Y3": 0.3938, "X4": 0.51047, "Y4": 0.3948, "page": 0}, {"Word": "Winn, D. M .; Blot, W. J .; Shy, C. M .; Pickle, L. W .; Toledo, M.", "Confidence": 0.89794, "X1": 0.48691, "Y1": 0.3922, "X2": 0.88482, "Y2": 0.392, "X3": 0.88482, "Y3": 0.4058, "X4": 0.48691, "Y4": 0.4058, "page": 0}, {"Word": "Adams, J. D .; Brunnemann, K. D .; Hecht, S. S .; Hoffmann, D.", "Confidence": 0.95736, "X1": 0.06937, "Y1": 0.4002, "X2": 0.45812, "Y2": 0.4, "X3": 0.45812, "Y3": 0.4138, "X4": 0.06937, "Y4": 0.4118, "page": 0}, {"Word": "ACS Symp. Ser. 1983, in press.", "Confidence": 0.93133, "X1": 0.08246, "Y1": 0.4132, "X2": 0.28927, "Y2": 0.413, "X3": 0.28927, "Y3": 0.4248, "X4": 0.08246, "Y4": 0.4238, "page": 0}, {"Word": "A .; Fraumeni, J. F ., Jr. N. Engl. J. Med. 1981, 304, 745.", "Confidence": 0.93836, "X1": 0.50916, "Y1": 0.4052, "X2": 0.86257, "Y2": 0.405, "X3": 0.86257, "Y3": 0.4188, "X4": 0.50916, "Y4": 0.4168, "page": 0}, {"Word": "Brunnemann, K. D .; Hoffmann, D. Carcinogenesis (N.Y.) 1981,", "Confidence": 0.92467, "X1": 0.0733, "Y1": 0.4232, "X2": 0.45681, "Y2": 0.423, "X3": 0.45681, "Y3": 0.4378, "X4": 0.0733, "Y4": 0.4358, "page": 0}, {"Word": "2, 1123.", "Confidence": 0.956, "X1": 0.08508, "Y1": 0.4342, "X2": 0.13874, "Y2": 0.434, "X3": 0.13874, "Y3": 0.4468, "X4": 0.08508, "Y4": 0.4468, "page": 0}, {"Word": "Received for review January 6, 1983. Accepted March 17, 1983.", "Confidence": 0.9224, "X1": 0.49215, "Y1": 0.4372, "X2": 0.8822, "Y2": 0.437, "X3": 0.8822, "Y3": 0.4498, "X4": 0.49215, "Y4": 0.4478, "page": 0}, {"Word": "Brunnemann, K. D .; Scott, J. C .; Hoffmann, D. Carcinogenesis", "Confidence": 0.86409, "X1": 0.0733, "Y1": 0.4472, "X2": 0.45942, "Y2": 0.447, "X3": 0.45942, "Y3": 0.4618, "X4": 0.0733, "Y4": 0.4598, "page": 0}, {"Word": "This study was supported by National Cancer Institute Grant", "Confidence": 0.95456, "X1": 0.49215, "Y1": 0.4492, "X2": 0.88351, "Y2": 0.449, "X3": 0.88351, "Y3": 0.4608, "X4": 0.49215, "Y4": 0.4598, "page": 0}, {"Word": "(N.Y.) 1982, 3, 693.", "Confidence": 0.924, "X1": 0.08377, "Y1": 0.4582, "X2": 0.20942, "Y2": 0.458, "X3": 0.20942, "Y3": 0.4718, "X4": 0.08377, "Y4": 0.4708, "page": 0}, {"Word": "1PO1-CA-29580. This study was presented in part at the 36th", "Confidence": 0.8761, "X1": 0.49346, "Y1": 0.4612, "X2": 0.88743, "Y2": 0.461, "X3": 0.88743, "Y3": 0.4738, "X4": 0.49346, "Y4": 0.4708, "page": 0}, {"Word": "' Brunnemann, K. D .; Yu, L; Hoffmann, D. Cancer Res. 1977, 37,", "Confidence": 0.81662, "X1": 0.06021, "Y1": 0.4702, "X2": 0.45942, "Y2": 0.47, "X3": 0.45812, "Y3": 0.4848, "X4": 0.06021, "Y4": 0.4828, "page": 0}, {"Word": "Tobacco Chemists' Research Conference, Raleigh, NC, Oct 25-27,", "Confidence": 0.91738, "X1": 0.49215, "Y1": 0.4722, "X2": 0.88089, "Y2": 0.472, "X3": 0.88089, "Y3": 0.4838, "X4": 0.49215, "Y4": 0.4838, "page": 0}, {"Word": "3218.", "Confidence": 0.748, "X1": 0.08246, "Y1": 0.4812, "X2": 0.12435, "Y2": 0.481, "X3": 0.12304, "Y3": 0.4938, "X4": 0.08377, "Y4": 0.4938, "page": 0}, {"Word": "1982. This paper is no. LXXIX in the series \"Chemical Studies", "Confidence": 0.91655, "X1": 0.49215, "Y1": 0.4842, "X2": 0.8822, "Y2": 0.484, "X3": 0.8822, "Y3": 0.4968, "X4": 0.49215, "Y4": 0.4958, "page": 0}, {"Word": "Enfmons, W. D. J. Am. Chem. Soc. 1957, 79, 5528.", "Confidence": 0.9431, "X1": 0.07199, "Y1": 0.4942, "X2": 0.38874, "Y2": 0.494, "X3": 0.38874, "Y3": 0.5078, "X4": 0.07199, "Y4": 0.5068, "page": 0}, {"Word": "on Tobacco Smoke\".", "Confidence": 0.903, "X1": 0.49346, "Y1": 0.4952, "X2": 0.62435, "Y2": 0.495, "X3": 0.62435, "Y3": 0.5078, "X4": 0.49346, "Y4": 0.5078, "page": 0}, {"Word": "An Alternate Method for the Analysis of N-Nitrosonornicotine in Tobacco", "Confidence": 0.9919, "X1": 0.06937, "Y1": 0.5622, "X2": 0.7945, "Y2": 0.562, "X3": 0.7945, "Y3": 0.5798, "X4": 0.06937, "Y4": 0.5788, "page": 0}, {"Word": "William J. Chamberlain and Richard F. Arrendale", "Confidence": 0.90757, "X1": 0.2945, "Y1": 0.5942, "X2": 0.66361, "Y2": 0.594, "X3": 0.66361, "Y3": 0.6098, "X4": 0.2945, "Y4": 0.6088, "page": 0}, {"Word": "A method is described for the analysis of N-nitrosonornicotine (NNN) in tobacco. This method has", "Confidence": 0.9898, "X1": 0.12696, "Y1": 0.6402, "X2": 0.8233, "Y2": 0.64, "X3": 0.8233, "Y3": 0.6558, "X4": 0.12696, "Y4": 0.6548, "page": 0}, {"Word": "been applied to a number of flue-cured tobacco samples, differing in nicotine and nornicotine contents,", "Confidence": 0.969, "X1": 0.12696, "Y1": 0.6552, "X2": 0.82199, "Y2": 0.655, "X3": 0.82199, "Y3": 0.6678, "X4": 0.12696, "Y4": 0.6668, "page": 0}, {"Word": "in order to determine whether or not there was a direct correlation between nicotine and nornicotine", "Confidence": 0.99494, "X1": 0.12565, "Y1": 0.6682, "X2": 0.82461, "Y2": 0.668, "X3": 0.8233, "Y3": 0.6808, "X4": 0.12565, "Y4": 0.6788, "page": 0}, {"Word": "levels and NNN level in tobacco leaf. There appears to be no correlation between the alkaloid content", "Confidence": 0.97294, "X1": 0.12565, "Y1": 0.6802, "X2": 0.82592, "Y2": 0.68, "X3": 0.82592, "Y3": 0.6938, "X4": 0.12565, "Y4": 0.6918, "page": 0}, {"Word": "of tobacco leaf and the level of NNN.", "Confidence": 0.98787, "X1": 0.12565, "Y1": 0.6922, "X2": 0.39921, "Y2": 0.692, "X3": 0.39921, "Y3": 0.7068, "X4": 0.12565, "Y4": 0.7058, "page": 0}, {"Word": "The tobacco-specific nitrosamines are the only known", "Confidence": 0.99229, "X1": 0.08246, "Y1": 0.7392, "X2": 0.45681, "Y2": 0.739, "X3": 0.45681, "Y3": 0.7528, "X4": 0.08246, "Y4": 0.7508, "page": 0}, {"Word": "smoke. However, many laboratories, including our own,", "Confidence": 0.96843, "X1": 0.49084, "Y1": 0.7392, "X2": 0.87958, "Y2": 0.739, "X3": 0.87958, "Y3": 0.7528, "X4": 0.49084, "Y4": 0.7518, "page": 0}, {"Word": "cigarette smoke carcinogens that are also found in un-", "Confidence": 0.97889, "X1": 0.06937, "Y1": 0.7522, "X2": 0.45419, "Y2": 0.752, "X3": 0.45419, "Y3": 0.7648, "X4": 0.06937, "Y4": 0.7628, "page": 0}, {"Word": "are not equipped with the expensive TEA. We have,", "Confidence": 0.99022, "X1": 0.49215, "Y1": 0.7522, "X2": 0.87958, "Y2": 0.752, "X3": 0.87958, "Y3": 0.7648, "X4": 0.49215, "Y4": 0.7658, "page": 0}, {"Word": "burned tobacco. Initially, Hoffmann et al. reported the", "Confidence": 0.95775, "X1": 0.06937, "Y1": 0.7642, "X2": 0.45681, "Y2": 0.764, "X3": 0.45681, "Y3": 0.7778, "X4": 0.06937, "Y4": 0.7758, "page": 0}, {"Word": "therefore, developed a method to separate NNN in tobacco", "Confidence": 0.99467, "X1": 0.49084, "Y1": 0.7632, "X2": 0.87827, "Y2": 0.763, "X3": 0.87827, "Y3": 0.7778, "X4": 0.49084, "Y4": 0.7778, "page": 0}, {"Word": "presence of N-nitrosonornicotine (NNN) in tobacco smoke", "Confidence": 0.817, "X1": 0.07068, "Y1": 0.7772, "X2": 0.45812, "Y2": 0.777, "X3": 0.45812, "Y3": 0.7918, "X4": 0.07068, "Y4": 0.7888, "page": 0}, {"Word": "by gas chromatography (GC) on fused silica glass capillary", "Confidence": 0.96044, "X1": 0.49084, "Y1": 0.7772, "X2": 0.87958, "Y2": 0.777, "X3": 0.87958, "Y3": 0.7908, "X4": 0.49084, "Y4": 0.7908, "page": 0}, {"Word": "and outlined a method for analysis, using gas chromatog-", "Confidence": 0.979, "X1": 0.07068, "Y1": 0.7902, "X2": 0.45812, "Y2": 0.79, "X3": 0.45812, "Y3": 0.8038, "X4": 0.07068, "Y4": 0.8018, "page": 0}, {"Word": "Superox-4 columns combined with detection by a nitro-", "Confidence": 0.9415, "X1": 0.49215, "Y1": 0.7912, "X2": 0.87958, "Y2": 0.791, "X3": 0.87958, "Y3": 0.8038, "X4": 0.49215, "Y4": 0.8038, "page": 0}, {"Word": "raphy-mass spectrometry (GC-MS) as the detection sys-", "Confidence": 0.97486, "X1": 0.07068, "Y1": 0.8032, "X2": 0.45681, "Y2": 0.803, "X3": 0.45681, "Y3": 0.8168, "X4": 0.07068, "Y4": 0.8158, "page": 0}, {"Word": "gen-phosphorus (N-P) thermionic detector.", "Confidence": 0.993, "X1": 0.49084, "Y1": 0.8032, "X2": 0.79974, "Y2": 0.803, "X3": 0.79974, "Y3": 0.8158, "X4": 0.49084, "Y4": 0.8168, "page": 0}, {"Word": "tem (Hoffmann et al ., 1973). Subsequently, a method", "Confidence": 0.96578, "X1": 0.06937, "Y1": 0.8162, "X2": 0.45681, "Y2": 0.816, "X3": 0.45681, "Y3": 0.8298, "X4": 0.06937, "Y4": 0.8278, "page": 0}, {"Word": "The major problem in using a N-P detector for NNN", "Confidence": 0.9912, "X1": 0.50131, "Y1": 0.8152, "X2": 0.88089, "Y2": 0.815, "X3": 0.88089, "Y3": 0.8288, "X4": 0.50131, "Y4": 0.8298, "page": 0}, {"Word": "(Hoffmann et al ., 1974; Hecht et al ., 1975) was developed", "Confidence": 0.98067, "X1": 0.07068, "Y1": 0.8292, "X2": 0.45942, "Y2": 0.829, "X3": 0.45812, "Y3": 0.8418, "X4": 0.07068, "Y4": 0.8398, "page": 0}, {"Word": "analysis is the removal of other nitrogen-containing com-", "Confidence": 0.99475, "X1": 0.49346, "Y1": 0.8292, "X2": 0.87827, "Y2": 0.829, "X3": 0.87827, "Y3": 0.8428, "X4": 0.49346, "Y4": 0.8418, "page": 0}, {"Word": "based on high-speed liquid chromatography and a thermal", "Confidence": 0.988, "X1": 0.06937, "Y1": 0.8412, "X2": 0.45812, "Y2": 0.841, "X3": 0.45812, "Y3": 0.8548, "X4": 0.06937, "Y4": 0.8528, "page": 0}, {"Word": "pounds, which could interfere, from the matrix. We have", "Confidence": 0.93944, "X1": 0.49215, "Y1": 0.8422, "X2": 0.88089, "Y2": 0.842, "X3": 0.88089, "Y3": 0.8558, "X4": 0.49215, "Y4": 0.8548, "page": 0}, {"Word": "energy analyzer (TEA) for GC detection and analysis. The", "Confidence": 0.97678, "X1": 0.07068, "Y1": 0.8542, "X2": 0.45812, "Y2": 0.854, "X3": 0.45812, "Y3": 0.8678, "X4": 0.07068, "Y4": 0.8668, "page": 0}, {"Word": "overcome this problem by alumina column chromatogra-", "Confidence": 0.97886, "X1": 0.49215, "Y1": 0.8552, "X2": 0.87958, "Y2": 0.855, "X3": 0.87958, "Y3": 0.8678, "X4": 0.49215, "Y4": 0.8678, "page": 0}, {"Word": "TEA has been shown to be the simplest and best detector", "Confidence": 0.99491, "X1": 0.07068, "Y1": 0.8662, "X2": 0.45812, "Y2": 0.866, "X3": 0.45812, "Y3": 0.8798, "X4": 0.07068, "Y4": 0.8778, "page": 0}, {"Word": "phy of the crude extract to yield a refined NNN fraction,", "Confidence": 0.986, "X1": 0.49084, "Y1": 0.8672, "X2": 0.88089, "Y2": 0.867, "X3": 0.88089, "Y3": 0.8798, "X4": 0.49084, "Y4": 0.8798, "page": 0}, {"Word": "for N-nitrosamines that occur in both tobacco and tobacco", "Confidence": 0.91933, "X1": 0.06937, "Y1": 0.8802, "X2": 0.45812, "Y2": 0.88, "X3": 0.45812, "Y3": 0.8928, "X4": 0.06937, "Y4": 0.8898, "page": 0}, {"Word": "sufficiently pure for GC analysis. Details of the metho-", "Confidence": 0.98022, "X1": 0.48953, "Y1": 0.8792, "X2": 0.87958, "Y2": 0.879, "X3": 0.87958, "Y3": 0.8928, "X4": 0.48953, "Y4": 0.8928, "page": 0}, {"Word": "dology are presented. In addition, the method was applied", "Confidence": 0.98778, "X1": 0.49084, "Y1": 0.8922, "X2": 0.88089, "Y2": 0.892, "X3": 0.88089, "Y3": 0.9058, "X4": 0.49084, "Y4": 0.9068, "page": 0}, {"Word": "in a correlation study between NNN and nicotine-nor-", "Confidence": 0.991, "X1": 0.49084, "Y1": 0.9062, "X2": 0.88089, "Y2": 0.906, "X3": 0.88089, "Y3": 0.9198, "X4": 0.49084, "Y4": 0.9188, "page": 0}, {"Word": "Tobacco Safety Research Unit, Agricultural Research", "Confidence": 0.992, "X1": 0.07984, "Y1": 0.9182, "X2": 0.45681, "Y2": 0.918, "X3": 0.45681, "Y3": 0.9328, "X4": 0.07984, "Y4": 0.9318, "page": 0}, {"Word": "nicotine levels of tobacco leaf.", "Confidence": 0.9892, "X1": 0.49346, "Y1": 0.9192, "X2": 0.70157, "Y2": 0.919, "X3": 0.70157, "Y3": 0.9318, "X4": 0.49346, "Y4": 0.9328, "page": 0}, {"Word": "Service, U.S. Department of Agriculture, Athens, Georgia", "Confidence": 0.99243, "X1": 0.06806, "Y1": 0.9322, "X2": 0.45812, "Y2": 0.932, "X3": 0.45812, "Y3": 0.9478, "X4": 0.06806, "Y4": 0.9458, "page": 0}, {"Word": "It has been shown that NNN in smoke is formed from", "Confidence": 0.91136, "X1": 0.50262, "Y1": 0.9322, "X2": 0.88089, "Y2": 0.932, "X3": 0.88089, "Y3": 0.9478, "X4": 0.50262, "Y4": 0.9468, "page": 0}, {"Word": "30613.", "Confidence": 0.955, "X1": 0.07068, "Y1": 0.9462, "X2": 0.11911, "Y2": 0.946, "X3": 0.1178, "Y3": 0.9578, "X4": 0.07068, "Y4": 0.9568, "page": 0}, {"Word": "both nicotine and nornicotine (Hoffmann et al ., 1977).", "Confidence": 0.98056, "X1": 0.49084, "Y1": 0.9462, "X2": 0.87958, "Y2": 0.946, "X3": 0.87958, "Y3": 0.9598, "X4": 0.49084, "Y4": 0.9588, "page": 0}, {"Word": "2021652346", "Confidence": 0.962, "X1": 0.92408, "Y1": 0.9582, "X2": 0.92539, "Y2": 0.958, "X3": 0.89791, "Y3": 0.9588, "X4": 0.89529, "Y4": 0.8068, "page": 0}, {"Word": "This article not subject to U.S. Copyright. Published 1983 by the American Chemical Society.", "Confidence": 0.80936, "X1": 0.2055, "Y1": 0.9712, "X2": 0.74476, "Y2": 0.971, "X3": 0.74476, "Y3": 0.9848, "X4": 0.2055, "Y4": 0.9858, "page": 0}], "words_data": [{"Word": "909", "Confidence": 0.686, "X1": 0.85864, "Y1": 0.0382, "X2": 0.88089, "Y2": 0.038, "X3": 0.88089, "Y3": 0.0468, "X4": 0.85864, "Y4": 0.0458, "page": 0, "Index": 0}, {"Word": "J.", "Confidence": 0.987, "X1": 0.35602, "Y1": 0.0352, "X2": 0.36911, "Y2": 0.035, "X3": 0.3678, "Y3": 0.0488, "X4": 0.35602, "Y4": 0.0488, "page": 0, "Index": 1}, {"Word": "Agric.", "Confidence": 0.817, "X1": 0.37173, "Y1": 0.0362, "X2": 0.40576, "Y2": 0.036, "X3": 0.40576, "Y3": 0.0488, "X4": 0.37173, "Y4": 0.0488, "page": 0, "Index": 2}, {"Word": "Food", "Confidence": 0.992, "X1": 0.40838, "Y1": 0.0362, "X2": 0.43979, "Y2": 0.036, "X3": 0.43979, "Y3": 0.0488, "X4": 0.40838, "Y4": 0.0488, "page": 0, "Index": 3}, {"Word": "Chem.", "Confidence": 0.685, "X1": 0.44372, "Y1": 0.0362, "X2": 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ffnb0048 | 0 | {"lines_data": [{"Word": "J. Agric. Food Cham. 1983, 31, 905-909", "Confidence": 0.87471, "X1": 0.31021, "Y1": 0.0072, "X2": 0.55497, "Y2": 0.007, "X3": 0.55497, "Y3": 0.0218, "X4": 0.31021, "Y4": 0.0228, "page": 0}, {"Word": "805", "Confidence": 0.611, "X1": 0.81283, "Y1": 0.0072, "X2": 0.84031, "Y2": 0.007, "X3": 0.83901, "Y3": 0.0188, "X4": 0.81283, "Y4": 0.0188, "page": 0}, {"Word": "group was dried for analysis after 2 days of refrigerated", "Confidence": 0.9725, "X1": 0.0301, "Y1": 0.0312, "X2": 0.41754, "Y2": 0.031, "X3": 0.41754, "Y3": 0.0448, "X4": 0.0301, "Y4": 0.0478, "page": 0}, {"Word": "ACKNOWLEDGMENT", "Confidence": 0.991, "X1": 0.45026, "Y1": 0.0302, "X2": 0.60733, "Y2": 0.03, "X3": 0.60733, "Y3": 0.0438, "X4": 0.45026, "Y4": 0.0458, "page": 0}, {"Word": "storage in the green state. 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Sci. 1970, 14, 164-166.", "Confidence": 0.90187, "X1": 0.45026, "Y1": 0.2532, "X2": 0.73953, "Y2": 0.253, "X3": 0.73953, "Y3": 0.2668, "X4": 0.45026, "Y4": 0.2668, "page": 0}, {"Word": "manifestation of the evidence that field-grown plants are", "Confidence": 0.98987, "X1": 0.0288, "Y1": 0.2572, "X2": 0.41623, "Y2": 0.257, "X3": 0.41623, "Y3": 0.2708, "X4": 0.0288, "Y4": 0.2688, "page": 0}, {"Word": "more lush and full bodied than plants grown under the", "Confidence": 0.9522, "X1": 0.0288, "Y1": 0.2702, "X2": 0.41885, "Y2": 0.27, "X3": 0.41885, "Y3": 0.2838, "X4": 0.0288, "Y4": 0.2828, "page": 0}, {"Word": "Gaines, T. Powell; Cutler, Horace G. J. Agric. Food Chem. 1974,", "Confidence": 0.95109, "X1": 0.45026, "Y1": 0.2652, "X2": 0.83901, "Y2": 0.265, "X3": 0.83901, "Y3": 0.2798, "X4": 0.45026, "Y4": 0.2788, "page": 0}, {"Word": "conditions maintained in our greenhouse. The magnitude", "Confidence": 0.98143, "X1": 0.0301, "Y1": 0.2832, "X2": 0.41754, "Y2": 0.283, "X3": 0.41754, "Y3": 0.2968, "X4": 0.0301, "Y4": 0.2958, "page": 0}, {"Word": "22 (4), 706-708.", "Confidence": 0.901, "X1": 0.46597, "Y1": 0.2782, "X2": 0.56806, "Y2": 0.278, "X3": 0.56806, "Y3": 0.2898, "X4": 0.46597, "Y4": 0.2898, "page": 0}, {"Word": "Kakie, T .; Sugizaki, Y. Scil Sci. Plant Nutr. (Tokyo) 1971, 17 (1);", "Confidence": 0.93492, "X1": 0.45288, "Y1": 0.2882, "X2": 0.83901, "Y2": 0.288, "X3": 0.83901, "Y3": 0.3038, "X4": 0.45288, "Y4": 0.3038, "page": 0}, {"Word": "of the difference is such that it cannot be due to varietal", "Confidence": 0.98642, "X1": 0.0288, "Y1": 0.2962, "X2": 0.41754, "Y2": 0.296, "X3": 0.41754, "Y3": 0.3108, "X4": 0.0288, "Y4": 0.3088, "page": 0}, {"Word": "27-36.", "Confidence": 0.955, "X1": 0.45942, "Y1": 0.3022, "X2": 0.51178, "Y2": 0.302, "X3": 0.51178, "Y3": 0.3138, "X4": 0.45942, "Y4": 0.3138, "page": 0}, {"Word": "variation between the two Coker varieties.", "Confidence": 0.96917, "X1": 0.0301, "Y1": 0.3092, "X2": 0.32853, "Y2": 0.309, "X3": 0.32853, "Y3": 0.3228, "X4": 0.0301, "Y4": 0.3218, "page": 0}, {"Word": "Kolthoff, L M .; Sandell, E. B .; Meehan, E. J .; Bruckenstein,", "Confidence": 0.85269, "X1": 0.45288, "Y1": 0.3122, "X2": 0.8377, "Y2": 0.312, "X3": 0.8377, "Y3": 0.3268, "X4": 0.45288, "Y4": 0.3268, "page": 0}, {"Word": "No recovery studies were made of starch added to to-", "Confidence": 0.9891, "X1": 0.03796, "Y1": 0.3212, "X2": 0.41754, "Y2": 0.321, "X3": 0.41754, "Y3": 0.3358, "X4": 0.03796, "Y4": 0.3348, "page": 0}, {"Word": "Stanley \"Quantitative Chemical Analysis\"; Macmillan: London,", "Confidence": 0.76133, "X1": 0.46859, "Y1": 0.3252, "X2": 0.83639, "Y2": 0.325, "X3": 0.83639, "Y3": 0.3388, "X4": 0.46859, "Y4": 0.3378, "page": 0}, {"Word": "bacco because it was felt that topically applied starch", "Confidence": 0.98856, "X1": 0.0288, "Y1": 0.3352, "X2": 0.42277, "Y2": 0.335, "X3": 0.42277, "Y3": 0.3498, "X4": 0.0288, "Y4": 0.3478, "page": 0}, {"Word": "1969; Chapter 44, p 845.", "Confidence": 0.9414, "X1": 0.46597, "Y1": 0.3382, "X2": 0.62435, "Y2": 0.338, "X3": 0.62304, "Y3": 0.3498, "X4": 0.46597, "Y4": 0.3498, "page": 0}, {"Word": "would wash off during the ethanol extraction.", "Confidence": 0.97986, "X1": 0.03141, "Y1": 0.3482, "X2": 0.34817, "Y2": 0.348, "X3": 0.34817, "Y3": 0.3628, "X4": 0.03141, "Y4": 0.3618, "page": 0}, {"Word": "Larsson, K .; Salomonsson, A .- C .; Theander, O .; \u00c5man, P. Potato", "Confidence": 0.87293, "X1": 0.45157, "Y1": 0.3482, "X2": 0.8377, "Y2": 0.348, "X3": 0.8377, "Y3": 0.3628, "X4": 0.45157, "Y4": 0.3618, "page": 0}, {"Word": "Res. 1979, 22 (4), 345-351.", "Confidence": 0.9756, "X1": 0.46335, "Y1": 0.3602, "X2": 0.63743, "Y2": 0.36, "X3": 0.63743, "Y3": 0.3728, "X4": 0.46335, "Y4": 0.3738, "page": 0}, {"Word": "CONCLUSIONS AND RECOMMENDATIONS", "Confidence": 0.99333, "X1": 0.03141, "Y1": 0.3662, "X2": 0.33901, "Y2": 0.366, "X3": 0.33901, "Y3": 0.3808, "X4": 0.03141, "Y4": 0.3808, "page": 0}, {"Word": "Rosa, Nestor Tob. Sci. 1971, 15, 58-61.", "Confidence": 0.92357, "X1": 0.45026, "Y1": 0.3732, "X2": 0.69634, "Y2": 0.373, "X3": 0.69634, "Y3": 0.3848, "X4": 0.45026, "Y4": 0.3848, "page": 0}, {"Word": "Salomonson, A .- C .; Theander, O .; \u00c5man, P. Sived. J. Agric. Res.", "Confidence": 0.84157, "X1": 0.45157, "Y1": 0.3842, "X2": 0.8377, "Y2": 0.384, "X3": 0.8377, "Y3": 0.3978, "X4": 0.45157, "Y4": 0.3978, "page": 0}, {"Word": "An enzymatic method for the determination of starch", "Confidence": 0.98825, "X1": 0.0445, "Y1": 0.3842, "X2": 0.41885, "Y2": 0.384, "X3": 0.41885, "Y3": 0.3988, "X4": 0.0445, "Y4": 0.3978, "page": 0}, {"Word": "1980, 10, 11-16.", "Confidence": 0.88233, "X1": 0.46466, "Y1": 0.3952, "X2": 0.57199, "Y2": 0.395, "X3": 0.57199, "Y3": 0.4078, "X4": 0.46466, "Y4": 0.4088, "page": 0}, {"Word": "in tobacco in various forms has been developed. With", "Confidence": 0.98644, "X1": 0.03141, "Y1": 0.3962, "X2": 0.41885, "Y2": 0.396, "X3": 0.41885, "Y3": 0.4108, "X4": 0.03141, "Y4": 0.4108, "page": 0}, {"Word": "slight modifications it has been applied to other starches.", "Confidence": 0.95033, "X1": 0.03141, "Y1": 0.4102, "X2": 0.41623, "Y2": 0.41, "X3": 0.41623, "Y3": 0.4238, "X4": 0.03141, "Y4": 0.4228, "page": 0}, {"Word": "Sensabaugh, A. J ., Jr .; Rush, Kenneth L. J. Assoc. Off. Anal.", "Confidence": 0.90092, "X1": 0.45026, "Y1": 0.4072, "X2": 0.8377, "Y2": 0.407, "X3": 0.8377, "Y3": 0.4218, "X4": 0.45026, "Y4": 0.4218, "page": 0}, {"Word": "While it is a somewhat laborious method requiring solvent", "Confidence": 0.99078, "X1": 0.03141, "Y1": 0.4242, "X2": 0.41623, "Y2": 0.424, "X3": 0.41623, "Y3": 0.4378, "X4": 0.0301, "Y4": 0.4358, "page": 0}, {"Word": "Chem. 1972, 55 (1), 109-213.", "Confidence": 0.978, "X1": 0.46728, "Y1": 0.4202, "X2": 0.64791, "Y2": 0.42, "X3": 0.64791, "Y3": 0.4328, "X4": 0.46728, "Y4": 0.4328, "page": 0}, {"Word": "\"Sigma Chemical Company Technical Bulletin No. 510\"; Sigma.", "Confidence": 0.804, "X1": 0.45419, "Y1": 0.4312, "X2": 0.84031, "Y2": 0.431, "X3": 0.84031, "Y3": 0.4448, "X4": 0.45419, "Y4": 0.4448, "page": 0}, {"Word": "extraction, starch solubilization, and two enzymatic", "Confidence": 0.99033, "X1": 0.03141, "Y1": 0.4372, "X2": 0.41492, "Y2": 0.437, "X3": 0.41492, "Y3": 0.4508, "X4": 0.03141, "Y4": 0.4488, "page": 0}, {"Word": "Chemical Co: St. Louis, MO, 1979.", "Confidence": 0.92517, "X1": 0.46073, "Y1": 0.4432, "X2": 0.69503, "Y2": 0.443, "X3": 0.69503, "Y3": 0.4558, "X4": 0.46073, "Y4": 0.4558, "page": 0}, {"Word": "treatments before the manual colorimetric readout, it is", "Confidence": 0.97137, "X1": 0.02749, "Y1": 0.4502, "X2": 0.41492, "Y2": 0.45, "X3": 0.41492, "Y3": 0.4638, "X4": 0.02749, "Y4": 0.4628, "page": 0}, {"Word": "Street, Harold V .; Close, John R. Clin. Chim. Acta 1956, 1,", "Confidence": 0.88433, "X1": 0.45157, "Y1": 0.4542, "X2": 0.84031, "Y2": 0.454, "X3": 0.84031, "Y3": 0.4678, "X4": 0.45157, "Y4": 0.4688, "page": 0}, {"Word": "felt to be an absolute representation of the starch content", "Confidence": 0.9296, "X1": 0.03141, "Y1": 0.4632, "X2": 0.41885, "Y2": 0.463, "X3": 0.41885, "Y3": 0.4768, "X4": 0.03141, "Y4": 0.4758, "page": 0}, {"Word": "256-268.", "Confidence": 0.984, "X1": 0.46597, "Y1": 0.4672, "X2": 0.52618, "Y2": 0.467, "X3": 0.52618, "Y3": 0.4778, "X4": 0.46597, "Y4": 0.4788, "page": 0}, {"Word": "\u00b7 of materials rather than a relative value. It has been ap-", "Confidence": 0.90775, "X1": 0.02094, "Y1": 0.4752, "X2": 0.41623, "Y2": 0.475, "X3": 0.41623, "Y3": 0.4898, "X4": 0.02094, "Y4": 0.4888, "page": 0}, {"Word": "Tso, T. C. \"Physiology and Biochemistry of Tobacco Plants\";", "Confidence": 0.87333, "X1": 0.45026, "Y1": 0.4792, "X2": 0.8377, "Y2": 0.479, "X3": 0.8377, "Y3": 0.4928, "X4": 0.45026, "Y4": 0.4918, "page": 0}, {"Word": "plied successfully to samples which could not be analyzed", "Confidence": 0.98178, "X1": 0.0301, "Y1": 0.4892, "X2": 0.41623, "Y2": 0.489, "X3": 0.41623, "Y3": 0.5028, "X4": 0.0301, "Y4": 0.5028, "page": 0}, {"Word": "Dowden, Hutchinson and Ross: Stroudsburg, PA, 1972; .", "Confidence": 0.82062, "X1": 0.46466, "Y1": 0.4912, "X2": 0.84686, "Y2": 0.491, "X3": 0.84686, "Y3": 0.5038, "X4": 0.46466, "Y4": 0.5038, "page": 0}, {"Word": "by an automated starch-iodine method.", "Confidence": 0.9892, "X1": 0.03141, "Y1": 0.5022, "X2": 0.3089, "Y2": 0.502, "X3": 0.3089, "Y3": 0.5148, "X4": 0.03141, "Y4": 0.5148, "page": 0}, {"Word": "Chapter 28, pp 305-306.", "Confidence": 0.971, "X1": 0.46859, "Y1": 0.5032, "X2": 0.62042, "Y2": 0.503, "X3": 0.62042, "Y3": 0.5158, "X4": 0.46859, "Y4": 0.5158, "page": 0}, {"Word": "Future improvements in speed and possibly in precision", "Confidence": 0.94788, "X1": 0.0445, "Y1": 0.5152, "X2": 0.41492, "Y2": 0.515, "X3": 0.41492, "Y3": 0.5298, "X4": 0.0445, "Y4": 0.5288, "page": 0}, {"Word": "can be made by automation of the glucose oxidase readout", "Confidence": 0.9933, "X1": 0.0301, "Y1": 0.5282, "X2": 0.41492, "Y2": 0.528, "X3": 0.41492, "Y3": 0.5418, "X4": 0.0301, "Y4": 0.5418, "page": 0}, {"Word": "Received for review November 5, 1982, Accepted April 1, 1983.", "Confidence": 0.9253, "X1": 0.45026, "Y1": 0.5312, "X2": 0.8377, "Y2": 0.531, "X3": 0.8377, "Y3": 0.5448, "X4": 0.45026, "Y4": 0.5438, "page": 0}, {"Word": "using a Technicon AutoAnalyzer II system or a Yellow", "Confidence": 0.95989, "X1": 0.0301, "Y1": 0.5412, "X2": 0.41623, "Y2": 0.541, "X3": 0.41623, "Y3": 0.5558, "X4": 0.0301, "Y4": 0.5558, "page": 0}, {"Word": "This paper was presented at the Southeastern Regional Meeting", "Confidence": 0.93, "X1": 0.44895, "Y1": 0.5432, "X2": 0.83901, "Y2": 0.543, "X3": 0.83901, "Y3": 0.5558, "X4": 0.44895, "Y4": 0.5558, "page": 0}, {"Word": "of the American Chemical Society, Birmingham, AL, Nov 2, 1982.", "Confidence": 0.9036, "X1": 0.45026, "Y1": 0.5542, "X2": 0.83901, "Y2": 0.554, "X3": 0.83901, "Y3": 0.5668, "X4": 0.45026, "Y4": 0.5668, "page": 0}, {"Word": "Springs Instrument Co. Model 27 industrial analyzer.", "Confidence": 0.94657, "X1": 0.0288, "Y1": 0.5532, "X2": 0.40445, "Y2": 0.553, "X3": 0.40445, "Y3": 0.5688, "X4": 0.0288, "Y4": 0.5688, "page": 0}, {"Word": "NO3 in filler not well correlated in th NON, but did the unk Sue Tati", "Confidence": 0.724, "X1": 0.06545, "Y1": 0.5762, "X2": 0.87042, "Y2": 0.576, "X3": 0.87042, "Y3": 0.5998, "X4": 0.06414, "Y4": 0.5988, "page": 0}, {"Word": "Ior blonds not single composent", "Confidence": 0.5228, "X1": 0.56283, "Y1": 0.5932, "X2": 0.85471, "Y2": 0.593, "X3": 0.85471, "Y3": 0.6098, "X4": 0.56283, "Y4": 0.6068, "page": 0}, {"Word": "N-Nitrosoproline, an Indicator for N-Nitrosation of Amines in Processed Tobacco", "Confidence": 0.9878, "X1": 0.0301, "Y1": 0.6052, "X2": 0.81806, "Y2": 0.605, "X3": 0.81806, "Y3": 0.6238, "X4": 0.0301, "Y4": 0.6238, "page": 0}, {"Word": "INA - Killer", "Confidence": 0.55633, "X1": 0.0, "Y1": 0.6252, "X2": 0.12696, "Y2": 0.625, "X3": 0.12827, "Y3": 0.6468, "X4": 0.00131, "Y4": 0.6528, "page": 0}, {"Word": "Klaus D. Brunnemann, John C. Scott, and Dietrich Hoffmann\"", "Confidence": 0.91844, "X1": 0.21204, "Y1": 0.6332, "X2": 0.65445, "Y2": 0.633, "X3": 0.65445, "Y3": 0.6488, "X4": 0.21204, "Y4": 0.6488, "page": 0}, {"Word": "N-Nitrosoproline (NPRO) was isolated from processed tobacco; a method for ite quantitative assessment", "Confidence": 0.88654, "X1": 0.08508, "Y1": 0.6722, "X2": 0.78403, "Y2": 0.672, "X3": 0.78403, "Y3": 0.6868, "X4": 0.08508, "Y4": 0.6868, "page": 0}, {"Word": "was developed, based on the enrichment of NPRO by solvent distributions, derivatization to its methyl", "Confidence": 0.98433, "X1": 0.08639, "Y1": 0.6862, "X2": 0.78141, "Y2": 0.686, "X3": 0.78141, "Y3": 0.6988, "X4": 0.08639, "Y4": 0.6998, "page": 0}, {"Word": "ester, and gas chromatography with a thermal energy analyzer (detection limit 0.5 ng/g of tobacco).", "Confidence": 0.98893, "X1": 0.08639, "Y1": 0.6982, "X2": 0.7801, "Y2": 0.698, "X3": 0.7801, "Y3": 0.7118, "X4": 0.08639, "Y4": 0.7128, "page": 0}, {"Word": "Cigarette and cigar tobaccos contained 0.33-2.3 ppm of NPRO; chewing tobacco and snuff had levels", "Confidence": 0.98433, "X1": 0.08639, "Y1": 0.7112, "X2": 0.78141, "Y2": 0.711, "X3": 0.78141, "Y3": 0.7248, "X4": 0.08639, "Y4": 0.7258, "page": 0}, {"Word": "of 0.45-21.8 ppm. On the basis of the analyses of 14 tobacco products, the formation of the noncar-", "Confidence": 0.96056, "X1": 0.08901, "Y1": 0.7252, "X2": 0.7801, "Y2": 0.725, "X3": 0.7801, "Y3": 0.7388, "X4": 0.08901, "Y4": 0.7378, "page": 0}, {"Word": "cinogenic NPRO is significantly correlated with the formation of N'-nitrosonornicotine and the sum", "Confidence": 0.96769, "X1": 0.0877, "Y1": 0.7372, "X2": 0.7801, "Y2": 0.737, "X3": 0.7801, "Y3": 0.7508, "X4": 0.0877, "Y4": 0.7508, "page": 0}, {"Word": "of the carcinogenic tobacco-specific N-nitrosamines (TSNA). Fine-cut snuff is relatively rich in NPRO", "Confidence": 0.96577, "X1": 0.09031, "Y1": 0.7502, "X2": 0.7801, "Y2": 0.75, "X3": 0.7801, "Y3": 0.7638, "X4": 0.09031, "Y4": 0.7638, "page": 0}, {"Word": "as well as in TSNA. The latter are the only known carcinogens in snuff tobaccos where they occur in", "Confidence": 0.95337, "X1": 0.08901, "Y1": 0.7632, "X2": 0.7801, "Y2": 0.763, "X3": 0.7801, "Y3": 0.7768, "X4": 0.08901, "Y4": 0.7768, "page": 0}, {"Word": "relatively high concentrations. It is suggested that efforts be undertaken to inhibit N-nitrosamine", "Confidence": 0.97462, "X1": 0.08639, "Y1": 0.7762, "X2": 0.78141, "Y2": 0.776, "X3": 0.78141, "Y3": 0.7888, "X4": 0.08639, "Y4": 0.7898, "page": 0}, {"Word": "formation, especially during the preparation of fine-cut snuff. NPRO was not detected in cigarette smoke", "Confidence": 0.97213, "X1": 0.0877, "Y1": 0.7892, "X2": 0.78272, "Y2": 0.789, "X3": 0.78272, "Y3": 0.8028, "X4": 0.0877, "Y4": 0.8038, "page": 0}, {"Word": "(<1 ng/cigarette).", "Confidence": 0.819, "X1": 0.0877, "Y1": 0.8032, "X2": 0.21728, "Y2": 0.803, "X3": 0.21728, "Y3": 0.8178, "X4": 0.0877, "Y4": 0.8168, "page": 0}, {"Word": "Tobacco and tobacco smoke contain three types of", "Confidence": 0.9875, "X1": 0.0445, "Y1": 0.8402, "X2": 0.41885, "Y2": 0.84, "X3": 0.41754, "Y3": 0.8548, "X4": 0.0445, "Y4": 0.8538, "page": 0}, {"Word": "agricultural chemical, and the tobacco-specific N-nitros-", "Confidence": 0.97483, "X1": 0.45026, "Y1": 0.8392, "X2": 0.8377, "Y2": 0.839, "X3": 0.8377, "Y3": 0.8538, "X4": 0.45026, "Y4": 0.8538, "page": 0}, {"Word": "N-nitrosamines, namely, the volatile nitrosamines, N-", "Confidence": 0.95067, "X1": 0.03141, "Y1": 0.8542, "X2": 0.42016, "Y2": 0.854, "X3": 0.42016, "Y3": 0.8668, "X4": 0.03141, "Y4": 0.8658, "page": 0}, {"Word": "amines (Hoffmann et al ., 1981; Brunnemann et al ., 1982).", "Confidence": 0.91264, "X1": 0.45026, "Y1": 0.8522, "X2": 0.8377, "Y2": 0.852, "X3": 0.8377, "Y3": 0.8658, "X4": 0.45026, "Y4": 0.8668, "page": 0}, {"Word": "These agents are not present in freshly cut green leaves", "Confidence": 0.9873, "X1": 0.45157, "Y1": 0.8652, "X2": 0.8377, "Y2": 0.865, "X3": 0.8377, "Y3": 0.8778, "X4": 0.45157, "Y4": 0.8788, "page": 0}, {"Word": "nitrosodiethanolamine, formed from the residue of an", "Confidence": 0.95729, "X1": 0.0301, "Y1": 0.8652, "X2": 0.41885, "Y2": 0.865, "X3": 0.41885, "Y3": 0.8788, "X4": 0.0301, "Y4": 0.8788, "page": 0}, {"Word": "but are formed during tobacco processing (Hecht et al .,", "Confidence": 0.9793, "X1": 0.45026, "Y1": 0.8782, "X2": 0.8377, "Y2": 0.878, "X3": 0.8377, "Y3": 0.8918, "X4": 0.45026, "Y4": 0.8918, "page": 0}, {"Word": "1978; Adams et al ., 1983). All of the N-nitrosamines so", "Confidence": 0.97018, "X1": 0.45026, "Y1": 0.8912, "X2": 0.8377, "Y2": 0.891, "X3": 0.8377, "Y3": 0.9048, "X4": 0.45026, "Y4": 0.9038, "page": 0}, {"Word": "Naylor Dans Institute for Disease Prevention, American", "Confidence": 0.934, "X1": 0.03796, "Y1": 0.9032, "X2": 0.41754, "Y2": 0.903, "X3": 0.41754, "Y3": 0.9188, "X4": 0.03665, "Y4": 0.9168, "page": 0}, {"Word": "far identified in tobacco products are known carcinogens", "Confidence": 0.91987, "X1": 0.45026, "Y1": 0.9052, "X2": 0.83901, "Y2": 0.905, "X3": 0.83901, "Y3": 0.9188, "X4": 0.45026, "Y4": 0.9178, "page": 0}, {"Word": "Health Foundation, Valhalla, New York 10595.", "Confidence": 0.96383, "X1": 0.0301, "Y1": 0.9172, "X2": 0.36257, "Y2": 0.917, "X3": 0.36257, "Y3": 0.9328, "X4": 0.0301, "Y4": 0.9318, "page": 0}, {"Word": "(U.S. Surgeon General, 1982).", "Confidence": 0.98375, "X1": 0.45026, "Y1": 0.9182, "X2": 0.65969, "Y2": 0.918, "X3": 0.65969, "Y3": 0.9318, "X4": 0.45026, "Y4": 0.9328, 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Abbreviations: NDMA = nitrosodimethylamine; NDEA = nitrosodiethylamine; NDPA =", "Confidence": 0.83727, "X1": 0.06675, "Y1": 0.2422, "X2": 0.86257, "Y2": 0.242, "X3": 0.86257, "Y3": 0.2548, "X4": 0.06675, "Y4": 0.2588, "page": 0}, {"Word": "nitrosodipropylamine; NDBA = nitrosodibutylamine; NPIP = nitrosopiperidine; NPYR = nitrosopyrrolidine; NMOR = nitro-", "Confidence": 0.81362, "X1": 0.05497, "Y1": 0.2532, "X2": 0.86387, "Y2": 0.253, "X3": 0.86387, "Y3": 0.2658, "X4": 0.05497, "Y4": 0.2698, "page": 0}, {"Word": "somorpholine; VNA = volatile nitrosamines; n.d. = not detected (<0.5 ppb). . Numbers indicate length in millimeters of", "Confidence": 0.94, "X1": 0.05759, "Y1": 0.2652, "X2": 0.85209, "Y2": 0.265, "X3": 0.85209, "Y3": 0.2778, "X4": 0.05759, "Y4": 0.2818, "page": 0}, {"Word": "cigarettes; P = filter; NF = nonfilter.", "Confidence": 0.77171, "X1": 0.05497, "Y1": 0.2802, "X2": 0.29581, "Y2": 0.28, "X3": 0.29581, "Y3": 0.2928, "X4": 0.05497, "Y4": 0.2928, "page": 0}, {"Word": "nornicotine. As to be expected, the nitrosation of proline", "Confidence": 0.95233, "X1": 0.48298, "Y1": 0.3022, "X2": 0.87304, "Y2": 0.302, "X3": 0.87304, "Y3": 0.3158, "X4": 0.48298, "Y4": 0.3178, "page": 0}, {"Word": "Table III. Statistical Evaluations (Commercial", "Confidence": 0.8548, "X1": 0.05497, "Y1": 0.3052, "X2": 0.3678, "Y2": 0.305, "X3": 0.3678, "Y3": 0.3188, "X4": 0.05497, "Y4": 0.3188, "page": 0}, {"Word": "Tobacco Productsy", "Confidence": 0.6555, "X1": 0.05759, "Y1": 0.3182, "X2": 0.18979, "Y2": 0.318, "X3": 0.18979, "Y3": 0.3288, "X4": 0.05759, "Y4": 0.3298, "page": 0}, {"Word": "to NPRO is also proportionately high (3.7%), demon-", "Confidence": 0.98512, "X1": 0.48298, "Y1": 0.3152, "X2": 0.87173, "Y2": 0.315, "X3": 0.87304, "Y3": 0.3288, "X4": 0.48298, "Y4": 0.3298, "page": 0}, {"Word": "no. in", "Confidence": 0.9485, "X1": 0.07723, "Y1": 0.3362, "X2": 0.1178, "Y2": 0.336, "X3": 0.1178, "Y3": 0.3468, "X4": 0.07723, "Y4": 0.3478, "page": 0}, {"Word": "independent", "Confidence": 0.792, "X1": 0.15576, "Y1": 0.3352, "X2": 0.24215, "Y2": 0.335, "X3": 0.24215, "Y3": 0.3468, "X4": 0.15576, "Y4": 0.3458, "page": 0}, {"Word": "dependent", "Confidence": 0.991, "X1": 0.27618, "Y1": 0.3352, "X2": 0.34817, "Y2": 0.335, "X3": 0.34817, "Y3": 0.3448, "X4": 0.27618, "Y4": 0.3458, "page": 0}, {"Word": "strating further that the processing to fine-cut snuff en-", "Confidence": 0.92456, "X1": 0.48429, "Y1": 0.3292, "X2": 0.87173, "Y2": 0.329, "X3": 0.87304, "Y3": 0.3418, "X4": 0.48429, "Y4": 0.3438, "page": 0}, {"Word": "model", "Confidence": 0.994, "X1": 0.07723, "Y1": 0.3462, "X2": 0.12042, "Y2": 0.346, "X3": 0.12042, "Y3": 0.3578, "X4": 0.07853, "Y4": 0.3588, "page": 0}, {"Word": "variable", "Confidence": 0.942, "X1": 0.16885, "Y1": 0.3472, "X2": 0.22382, "Y2": 0.347, "X3": 0.22382, "Y3": 0.3578, "X4": 0.16885, "Y4": 0.3578, "page": 0}, {"Word": "Variable", "Confidence": 0.659, "X1": 0.28534, "Y1": 0.3472, "X2": 0.33901, "Y2": 0.347, "X3": 0.34031, "Y3": 0.3568, "X4": 0.28534, "Y4": 0.3578, "page": 0}, {"Word": "hances the potential for the formation of N-nitrosamines.", "Confidence": 0.93625, "X1": 0.48298, "Y1": 0.3422, "X2": 0.87435, "Y2": 0.342, "X3": 0.87435, "Y3": 0.3548, "X4": 0.48298, "Y4": 0.3568, "page": 0}, {"Word": "This observation cannot be explained by the relative high", "Confidence": 0.98989, "X1": 0.48298, "Y1": 0.3542, "X2": 0.87435, "Y2": 0.354, "X3": 0.87435, "Y3": 0.3678, "X4": 0.48298, "Y4": 0.3708, "page": 0}, {"Word": "1", "Confidence": 0.994, "X1": 0.09293, "Y1": 0.3652, "X2": 0.10209, "Y2": 0.365, "X3": 0.10209, "Y3": 0.3748, "X4": 0.09424, "Y4": 0.3758, "page": 0}, {"Word": "NO.", "Confidence": 0.672, "X1": 0.13743, "Y1": 0.3632, "X2": 0.16623, "Y2": 0.363, "X3": 0.16492, "Y3": 0.3748, "X4": 0.13613, "Y4": 0.3748, "page": 0}, {"Word": "NNN", "Confidence": 0.081, "X1": 0.29319, "Y1": 0.3642, "X2": 0.32592, "Y2": 0.364, "X3": 0.32592, "Y3": 0.3748, "X4": 0.29319, "Y4": 0.3748, "page": 0}, {"Word": "0.592", "Confidence": 0.995, "X1": 0.36911, "Y1": 0.3632, "X2": 0.40838, "Y2": 0.363, "X3": 0.40707, "Y3": 0.3728, "X4": 0.3678, "Y4": 0.3738, "page": 0}, {"Word": "1", "Confidence": 0.995, "X1": 0.09162, "Y1": 0.3752, "X2": 0.10864, "Y2": 0.375, "X3": 0.10733, "Y3": 0.3858, "X4": 0.09162, "Y4": 0.3858, "page": 0}, {"Word": "nicotine", "Confidence": 0.991, "X1": 0.13743, "Y1": 0.3762, "X2": 0.19503, "Y2": 0.376, "X3": 0.19503, "Y3": 0.3868, "X4": 0.13743, "Y4": 0.3868, "page": 0}, {"Word": "NNN", "Confidence": 0.993, "X1": 0.29058, "Y1": 0.3752, "X2": 0.32984, "Y2": 0.375, "X3": 0.32984, "Y3": 0.3848, "X4": 0.29058, "Y4": 0.3848, "page": 0}, {"Word": "0.238.", "Confidence": 0.662, "X1": 0.36911, "Y1": 0.3742, "X2": 0.4123, "Y2": 0.374, "X3": 0.41099, "Y3": 0.3838, "X4": 0.36911, "Y4": 0.3828, "page": 0}, {"Word": "nitrate content of the snuff tobacco (~3.5%) alone. The", "Confidence": 0.90967, "X1": 0.4856, "Y1": 0.3672, "X2": 0.87565, "Y2": 0.367, "X3": 0.87565, "Y3": 0.3808, "X4": 0.4856, "Y4": 0.3838, "page": 0}, {"Word": "1", "Confidence": 0.991, "X1": 0.09293, "Y1": 0.3872, "X2": 0.1034, "Y2": 0.387, "X3": 0.10471, "Y3": 0.3978, "X4": 0.09424, "Y4": 0.3978, "page": 0}, {"Word": "NO.", "Confidence": 0.785, "X1": 0.13874, "Y1": 0.3872, "X2": 0.16623, "Y2": 0.387, "X3": 0.16623, "Y3": 0.3968, "X4": 0.13874, "Y4": 0.3978, "page": 0}, {"Word": "NPRO", "Confidence": 0.987, "X1": 0.28927, "Y1": 0.3872, "X2": 0.33639, "Y2": 0.387, "X3": 0.33508, "Y3": 0.3978, "X4": 0.28927, "Y4": 0.3968, "page": 0}, {"Word": "0.522", "Confidence": 0.941, "X1": 0.3678, "Y1": 0.3862, "X2": 0.40707, "Y2": 0.386, "X3": 0.40707, "Y3": 0.3958, "X4": 0.3678, "Y4": 0.3958, "page": 0}, {"Word": "values for volatile N-nitrosamines are not especially high,", "Confidence": 0.96788, "X1": 0.48168, "Y1": 0.3812, "X2": 0.87565, "Y2": 0.381, "X3": 0.87565, "Y3": 0.3938, "X4": 0.48168, "Y4": 0.3958, "page": 0}, {"Word": "PRO", "Confidence": 0.674, "X1": 0.13743, "Y1": 0.3962, "X2": 0.17277, "Y2": 0.396, "X3": 0.17277, "Y3": 0.4068, "X4": 0.13743, "Y4": 0.4078, "page": 0}, {"Word": "NPRO", "Confidence": 0.985, "X1": 0.28927, "Y1": 0.3972, "X2": 0.33639, "Y2": 0.397, "X3": 0.33639, "Y3": 0.4078, "X4": 0.28927, "Y4": 0.4078, "page": 0}, {"Word": "0.052", "Confidence": 0.846, "X1": 0.36911, "Y1": 0.3962, "X2": 0.40707, "Y2": 0.396, "X3": 0.40707, "Y3": 0.4068, "X4": 0.37042, "Y4": 0.4068, "page": 0}, {"Word": ".- with the possible exception of N-nitrosopyrrolidine (0.12", "Confidence": 0.85775, "X1": 0.46728, "Y1": 0.3942, "X2": 0.87435, "Y2": 0.394, "X3": 0.87435, "Y3": 0.4078, "X4": 0.46728, "Y4": 0.4098, "page": 0}, {"Word": "1", "Confidence": 0.991, "X1": 0.09031, "Y1": 0.3992, "X2": 0.10602, "Y2": 0.399, "X3": 0.10602, "Y3": 0.4088, "X4": 0.09162, "Y4": 0.4098, "page": 0}, {"Word": "NPRO", "Confidence": 0.988, "X1": 0.13743, "Y1": 0.4092, "X2": 0.18194, "Y2": 0.409, "X3": 0.18194, "Y3": 0.4198, "X4": 0.13743, "Y4": 0.4198, "page": 0}, {"Word": "NNN", "Confidence": 0.998, "X1": 0.28927, "Y1": 0.4092, "X2": 0.32984, "Y2": 0.409, "X3": 0.32984, "Y3": 0.4198, "X4": 0.28927, "Y4": 0.4188, "page": 0}, {"Word": "0.961", "Confidence": 0.941, "X1": 0.37042, "Y1": 0.4082, "X2": 0.40707, "Y2": 0.408, "X3": 0.40707, "Y3": 0.4188, "X4": 0.37173, "Y4": 0.4188, "page": 0}, {"Word": "ppm) and N-nitrosomorpholine (0.04 ppm). These two", "Confidence": 0.97386, "X1": 0.48429, "Y1": 0.4072, "X2": 0.87565, "Y2": 0.407, "X3": 0.87565, "Y3": 0.4208, "X4": 0.48429, "Y4": 0.4238, "page": 0}, {"Word": "1", "Confidence": 0.991, "X1": 0.09293, "Y1": 0.4212, "X2": 0.10471, "Y2": 0.421, "X3": 0.10471, "Y3": 0.4308, "X4": 0.09293, "Y4": 0.4308, "page": 0}, {"Word": "NPRO", "Confidence": 0.654, "X1": 0.14005, "Y1": 0.4202, "X2": 0.17932, "Y2": 0.42, "X3": 0.17801, "Y3": 0.4308, "X4": 0.13874, "Y4": 0.4298, "page": 0}, {"Word": "TSNA", "Confidence": 0.984, "X1": 0.29058, "Y1": 0.4212, "X2": 0.33246, "Y2": 0.421, "X3": 0.33246, "Y3": 0.4308, "X4": 0.29188, "Y4": 0.4308, "page": 0}, {"Word": "0.899", "Confidence": 0.881, "X1": 0.3678, "Y1": 0.4202, "X2": 0.40838, "Y2": 0.42, "X3": 0.40838, "Y3": 0.4298, "X4": 0.36911, "Y4": 0.4298, "page": 0}, {"Word": "compounds are the least volatile ones of the group of", "Confidence": 0.9918, "X1": 0.4856, "Y1": 0.4212, "X2": 0.87565, "Y2": 0.421, "X3": 0.87565, "Y3": 0.4338, "X4": 0.4856, "Y4": 0.4358, "page": 0}, {"Word": "0.966", "Confidence": 0.994, "X1": 0.36649, "Y1": 0.4382, "X2": 0.40707, "Y2": 0.438, "X3": 0.40707, "Y3": 0.4478, "X4": 0.36649, "Y4": 0.4488, "page": 0}, {"Word": "volatile N-nitrosamines. Since the amounts of carcinogenic", "Confidence": 0.89086, "X1": 0.4856, "Y1": 0.4332, "X2": 0.87696, "Y2": 0.433, "X3": 0.87696, "Y3": 0.4468, "X4": 0.4856, "Y4": 0.4488, "page": 0}, {"Word": "NPRO, NO,", "Confidence": 0.9385, "X1": 0.13874, "Y1": 0.4382, "X2": 0.2199, "Y2": 0.438, "X3": 0.2199, "Y3": 0.4498, "X4": 0.13874, "Y4": 0.4498, "page": 0}, {"Word": "NNN", "Confidence": 0.994, "X1": 0.28927, "Y1": 0.4372, "X2": 0.32853, "Y2": 0.437, "X3": 0.32853, "Y3": 0.4488, "X4": 0.28927, "Y4": 0.4498, "page": 0}, {"Word": "NPRO, NO,", "Confidence": 0.9175, "X1": 0.13743, "Y1": 0.4492, "X2": 0.2212, "Y2": 0.449, "X3": 0.2212, "Y3": 0.4608, "X4": 0.13743, "Y4": 0.4608, "page": 0}, {"Word": "TSNA", "Confidence": 0.982, "X1": 0.28927, "Y1": 0.4502, "X2": 0.33246, "Y2": 0.45, "X3": 0.33115, "Y3": 0.4608, "X4": 0.28927, "Y4": 0.4608, "page": 0}, {"Word": "0.918", "Confidence": 0.745, "X1": 0.36649, "Y1": 0.4492, "X2": 0.40838, "Y2": 0.449, "X3": 0.40838, "Y3": 0.4598, "X4": 0.3678, "Y4": 0.4588, "page": 0}, {"Word": "nitrosamines are about 2 orders of magnitude higher in .", "Confidence": 0.9485, "X1": 0.48691, "Y1": 0.4472, "X2": 0.88482, "Y2": 0.447, "X3": 0.88482, "Y3": 0.4598, "X4": 0.48691, "Y4": 0.4618, "page": 0}, {"Word": "2", "Confidence": 0.843, "X1": 0.09031, "Y1": 0.4592, "X2": 0.10864, "Y2": 0.459, "X3": 0.10995, "Y3": 0.4688, "X4": 0.09162, "Y4": 0.4708, "page": 0}, {"Word": "NPRO, PRO", "Confidence": 0.979, "X1": 0.13874, "Y1": 0.4612, "X2": 0.2212, "Y2": 0.461, "X3": 0.2212, "Y3": 0.4718, "X4": 0.13874, "Y4": 0.4718, "page": 0}, {"Word": "NNN", "Confidence": 0.993, "X1": 0.29058, "Y1": 0.4612, "X2": 0.32853, "Y2": 0.461, "X3": 0.32853, "Y3": 0.4708, "X4": 0.29188, "Y4": 0.4718, "page": 0}, {"Word": "0.962", "Confidence": 0.955, "X1": 0.36649, "Y1": 0.4602, "X2": 0.40576, "Y2": 0.46, "X3": 0.40707, "Y3": 0.4708, "X4": 0.3678, "Y4": 0.4698, "page": 0}, {"Word": "fine-cut snuff than in any other nonoccupational materials .", "Confidence": 0.88989, "X1": 0.48298, "Y1": 0.4592, "X2": 0.88351, "Y2": 0.459, "X3": 0.88351, "Y3": 0.4718, "X4": 0.48298, "Y4": 0.4748, "page": 0}, {"Word": "NPRO, PRO", "Confidence": 0.9035, "X1": 0.13874, "Y1": 0.4722, "X2": 0.22382, "Y2": 0.472, "X3": 0.22382, "Y3": 0.4828, "X4": 0.13874, "Y4": 0.4828, "page": 0}, {"Word": "TSNA", "Confidence": 0.985, "X1": 0.28927, "Y1": 0.4722, "X2": 0.33508, "Y2": 0.472, "X3": 0.33508, "Y3": 0.4828, "X4": 0.28927, "Y4": 0.4828, "page": 0}, {"Word": "0.903", "Confidence": 0.992, "X1": 0.36649, "Y1": 0.4712, "X2": 0.40969, "Y2": 0.471, "X3": 0.40969, "Y3": 0.4818, "X4": 0.36649, "Y4": 0.4818, "page": 0}, {"Word": "in man's environment, this observation strengthens our", "Confidence": 0.93871, "X1": 0.4856, "Y1": 0.4732, "X2": 0.87565, "Y2": 0.473, "X3": 0.87565, "Y3": 0.4858, "X4": 0.4856, "Y4": 0.4878, "page": 0}, {"Word": "NPRO, PRO, NO,", "Confidence": 0.89333, "X1": 0.13874, "Y1": 0.4892, "X2": 0.25654, "Y2": 0.489, "X3": 0.25654, "Y3": 0.5008, "X4": 0.13874, "Y4": 0.5008, "page": 0}, {"Word": "NNN", "Confidence": 0.998, "X1": 0.29188, "Y1": 0.4902, "X2": 0.32853, "Y2": 0.49, "X3": 0.32853, "Y3": 0.4998, "X4": 0.29188, "Y4": 0.4998, "page": 0}, {"Word": "0.966", "Confidence": 0.937, "X1": 0.36911, "Y1": 0.4892, "X2": 0.40707, "Y2": 0.489, "X3": 0.40707, "Y3": 0.4998, "X4": 0.37042, "Y4": 0.4998, "page": 0}, {"Word": "working hypothesis that the nitrosamines, especially the", "Confidence": 0.95757, "X1": 0.48691, "Y1": 0.4852, "X2": 0.87435, "Y2": 0.485, "X3": 0.87435, "Y3": 0.4988, "X4": 0.48691, "Y4": 0.5008, "page": 0}, {"Word": "3", "Confidence": 0.885, "X1": 0.09162, "Y1": 0.5022, "X2": 0.10733, "Y2": 0.502, "X3": 0.10733, "Y3": 0.5128, "X4": 0.09162, "Y4": 0.5128, "page": 0}, {"Word": "NPRO, PRO, NO,", "Confidence": 0.95433, "X1": 0.13874, "Y1": 0.5022, "X2": 0.26047, "Y2": 0.502, "X3": 0.26047, "Y3": 0.5138, "X4": 0.13874, "Y4": 0.5128, "page": 0}, {"Word": "TSNA", "Confidence": 0.987, "X1": 0.29188, "Y1": 0.5022, "X2": 0.33508, "Y2": 0.502, "X3": 0.33508, "Y3": 0.5128, "X4": 0.29188, "Y4": 0.5118, "page": 0}, {"Word": "0.918", "Confidence": 0.996, "X1": 0.37042, "Y1": 0.5012, "X2": 0.40838, "Y2": 0.501, "X3": 0.40838, "Y3": 0.5118, "X4": 0.37042, "Y4": 0.5118, "page": 0}, {"Word": "tobacco-specific N-nitrosamines, contribute significantly", "Confidence": 0.8495, "X1": 0.48691, "Y1": 0.4992, "X2": 0.87696, "Y2": 0.499, "X3": 0.87696, "Y3": 0.5118, "X4": 0.48691, "Y4": 0.5138, "page": 0}, {"Word": "to the increased risk of snuff dippers for cancer of the oral", "Confidence": 0.98917, "X1": 0.48691, "Y1": 0.5122, "X2": 0.87565, "Y2": 0.512, "X3": 0.87565, "Y3": 0.5248, "X4": 0.48691, "Y4": 0.5268, "page": 0}, {"Word": "\" Abbreviations: see footnote a of Table L", "Confidence": 0.8135, "X1": 0.07068, "Y1": 0.5182, "X2": 0.35471, "Y2": 0.518, "X3": 0.35471, "Y3": 0.5328, "X4": 0.07068, "Y4": 0.5328, "page": 0}, {"Word": "cavity (Winn et al ., 1981; Hoffmann and Adams, 1981).", "Confidence": 0.9681, "X1": 0.48691, "Y1": 0.5242, "X2": 0.87565, "Y2": 0.524, "X3": 0.87565, "Y3": 0.5368, "X4": 0.48691, "Y4": 0.5398, "page": 0}, {"Word": "Table I lists the analytical data from 13 commercial", "Confidence": 0.95433, "X1": 0.06675, "Y1": 0.5402, "X2": 0.45288, "Y2": 0.54, "X3": 0.45288, "Y3": 0.5538, "X4": 0.06675, "Y4": 0.5548, "page": 0}, {"Word": "While it may be difficult to document the role of TSNA", "Confidence": 0.98827, "X1": 0.48691, "Y1": 0.5372, "X2": 0.87827, "Y2": 0.537, "X3": 0.87827, "Y3": 0.5498, "X4": 0.48691, "Y4": 0.5528, "page": 0}, {"Word": "tobacco products and from the Kentucky reference ciga-", "Confidence": 0.98687, "X1": 0.06021, "Y1": 0.5542, "X2": 0.45288, "Y2": 0.554, "X3": 0.45288, "Y3": 0.5668, "X4": 0.06021, "Y4": 0.5668, "page": 0}, {"Word": "in oral cancer risk of snuff dippers, it is a fact that they", "Confidence": 0.96415, "X1": 0.48691, "Y1": 0.5502, "X2": 0.87958, "Y2": 0.55, "X3": 0.87958, "Y3": 0.5638, "X4": 0.48691, "Y4": 0.5658, "page": 0}, {"Word": "are the only known carcinogens in snuff. Therefore, the", "Confidence": 0.97556, "X1": 0.48691, "Y1": 0.5622, "X2": 0.87565, "Y2": 0.562, "X3": 0.87696, "Y3": 0.5768, "X4": 0.48691, "Y4": 0.5798, "page": 0}, {"Word": "rette 1RI for nitrate, nicotine, and N'-nitrosonornicotine,", "Confidence": 0.91614, "X1": 0.06021, "Y1": 0.5662, "X2": 0.45288, "Y2": 0.566, "X3": 0.45288, "Y3": 0.5798, "X4": 0.06021, "Y4": 0.5808, "page": 0}, {"Word": "the percentage of nicotine which is N-nitrosated to N\u00ba.", "Confidence": 0.88644, "X1": 0.06152, "Y1": 0.5782, "X2": 0.45157, "Y2": 0.578, "X3": 0.45157, "Y3": 0.5908, "X4": 0.06152, "Y4": 0.5938, "page": 0}, {"Word": "reduction of the carinogenic nitrosamines deriving from", "Confidence": 0.97457, "X1": 0.4856, "Y1": 0.5762, "X2": 0.87565, "Y2": 0.576, "X3": 0.87565, "Y3": 0.5898, "X4": 0.4856, "Y4": 0.5918, "page": 0}, {"Word": "nitrosonornicotine, total TSNA [N'-nitrosonornicotine,", "Confidence": 0.93625, "X1": 0.06283, "Y1": 0.5922, "X2": 0.45157, "Y2": 0.592, "X3": 0.45157, "Y3": 0.6048, "X4": 0.06283, "Y4": 0.6058, "page": 0}, {"Word": "the tobacco alkaloids should certainly be an important goal", "Confidence": 0.98289, "X1": 0.4856, "Y1": 0.5902, "X2": 0.87435, "Y2": 0.59, "X3": 0.87435, "Y3": 0.6028, "X4": 0.4856, "Y4": 0.6048, "page": 0}, {"Word": "4-(methylnitrosamino)-1-(3-pyridy!)-1-butanone, N\u00ba-", "Confidence": 0.215, "X1": 0.06021, "Y1": 0.6032, "X2": 0.45419, "Y2": 0.603, "X3": 0.45419, "Y3": 0.6178, "X4": 0.06021, "Y4": 0.6198, "page": 0}, {"Word": "for the modification of snuff products.", "Confidence": 0.95433, "X1": 0.4856, "Y1": 0.6042, "X2": 0.75654, "Y2": 0.604, "X3": 0.75654, "Y3": 0.6168, "X4": 0.4856, "Y4": 0.6168, "page": 0}, {"Word": "nitrosonanatabine, and N'-nitrosoanabasine], proline, and", "Confidence": 0.9296, "X1": 0.06021, "Y1": 0.6182, "X2": 0.45288, "Y2": 0.618, "X3": 0.45288, "Y3": 0.6318, "X4": 0.06021, "Y4": 0.6328, "page": 0}, {"Word": "Cigarette Smoke Analysis. Finally, we explored", "Confidence": 0.97683, "X1": 0.49869, "Y1": 0.6152, "X2": 0.87827, "Y2": 0.615, "X3": 0.87827, "Y3": 0.6288, "X4": 0.49869, "Y4": 0.6308, "page": 0}, {"Word": "NPRO, and the percentage of N-nitrosated proline. The", "Confidence": 0.99462, "X1": 0.06152, "Y1": 0.6302, "X2": 0.45157, "Y2": 0.63, "X3": 0.45157, "Y3": 0.6448, "X4": 0.06152, "Y4": 0.6448, "page": 0}, {"Word": "whether cigarette smoke contains NPRO and whether", "Confidence": 0.97871, "X1": 0.48822, "Y1": 0.6282, "X2": 0.87827, "Y2": 0.628, "X3": 0.87827, "Y3": 0.6418, "X4": 0.48822, "Y4": 0.6438, "page": 0}, {"Word": "results for up to seven volatile N-nitrosamines in the to-", "Confidence": 0.9943, "X1": 0.06152, "Y1": 0.6442, "X2": 0.45157, "Y2": 0.644, "X3": 0.45288, "Y3": 0.6578, "X4": 0.06152, "Y4": 0.6588, "page": 0}, {"Word": "proline or NPRO in tobacco gives rise to NPRO in ciga-", "Confidence": 0.99264, "X1": 0.48822, "Y1": 0.6422, "X2": 0.87565, "Y2": 0.642, "X3": 0.87565, "Y3": 0.6548, "X4": 0.48822, "Y4": 0.6568, "page": 0}, {"Word": "rette smoke. One hundred cigarettes were smoked under", "Confidence": 0.95775, "X1": 0.48691, "Y1": 0.6552, "X2": 0.87827, "Y2": 0.655, "X3": 0.87827, "Y3": 0.6678, "X4": 0.48691, "Y4": 0.6698, "page": 0}, {"Word": "bacco of the same 14 tobacco products are summarized in", "Confidence": 0.9872, "X1": 0.0589, "Y1": 0.6572, "X2": 0.4555, "Y2": 0.657, "X3": 0.4555, "Y3": 0.6708, "X4": 0.0589, "Y4": 0.6708, "page": 0}, {"Word": "Table IL", "Confidence": 0.7995, "X1": 0.06152, "Y1": 0.6692, "X2": 0.12827, "Y2": 0.669, "X3": 0.12827, "Y3": 0.6818, "X4": 0.06152, "Y4": 0.6838, "page": 0}, {"Word": "standard conditions with a 20-port automatic smoker (see", "Confidence": 0.95975, "X1": 0.48691, "Y1": 0.6682, "X2": 0.87827, "Y2": 0.668, "X3": 0.87958, "Y3": 0.6808, "X4": 0.48691, "Y4": 0.6828, "page": 0}, {"Word": "It was the goal of this study to explore whether the", "Confidence": 0.97445, "X1": 0.07461, "Y1": 0.6822, "X2": 0.45288, "Y2": 0.682, "X3": 0.45288, "Y3": 0.6978, "X4": 0.07461, "Y4": 0.6988, "page": 0}, {"Word": "Experimental Section) and the mainstream smoke was", "Confidence": 0.98171, "X1": 0.48691, "Y1": 0.6812, "X2": 0.88089, "Y2": 0.681, "X3": 0.88089, "Y3": 0.6938, "X4": 0.48691, "Y4": 0.6958, "page": 0}, {"Word": "trapped in two gas wash bottles containing a buffer solu-", "Confidence": 0.8802, "X1": 0.48691, "Y1": 0.6942, "X2": 0.87696, "Y2": 0.694, "X3": 0.87696, "Y3": 0.7078, "X4": 0.48691, "Y4": 0.7098, "page": 0}, {"Word": "noncarcinogenic N-nitrosoproline could serve as an indi-", "Confidence": 0.97, "X1": 0.0589, "Y1": 0.6972, "X2": 0.45419, "Y2": 0.697, "X3": 0.45419, "Y3": 0.7098, "X4": 0.0589, "Y4": 0.7108, "page": 0}, {"Word": "cator for the formation of the tobacco-specific N-nitros-", "Confidence": 0.98963, "X1": 0.06152, "Y1": 0.7092, "X2": 0.45419, "Y2": 0.709, "X3": 0.45419, "Y3": 0.7218, "X4": 0.06152, "Y4": 0.7228, "page": 0}, {"Word": "tion with ascorbic acid (pH 4.5; Hoffmann et al ., 1979).", "Confidence": 0.97964, "X1": 0.48691, "Y1": 0.7072, "X2": 0.87565, "Y2": 0.707, "X3": 0.87565, "Y3": 0.7198, "X4": 0.48691, "Y4": 0.7218, "page": 0}, {"Word": "amines of which 4-(methylnitrosamino)-1-(3-pyridy!)-1-", "Confidence": 0.762, "X1": 0.06152, "Y1": 0.7222, "X2": 0.45419, "Y2": 0.722, "X3": 0.45419, "Y3": 0.7358, "X4": 0.06152, "Y4": 0.7368, "page": 0}, {"Word": "The actual analytical procedure beginning with repeated", "Confidence": 0.98771, "X1": 0.48691, "Y1": 0.7202, "X2": 0.87827, "Y2": 0.72, "X3": 0.87827, "Y3": 0.7338, "X4": 0.48691, "Y4": 0.7358, "page": 0}, {"Word": "ethyl acetate extractions was identical with the procedure", "Confidence": 0.96562, "X1": 0.48953, "Y1": 0.7342, "X2": 0.87827, "Y2": 0.734, "X3": 0.87827, "Y3": 0.7468, "X4": 0.48953, "Y4": 0.7488, "page": 0}, {"Word": "butanone is a strong animal carcinogen (U.S. Surgeon\"", "Confidence": 0.95088, "X1": 0.06021, "Y1": 0.7352, "X2": 0.46073, "Y2": 0.735, "X3": 0.46073, "Y3": 0.7488, "X4": 0.06021, "Y4": 0.7508, "page": 0}, {"Word": "General, 1982). As summarized in Table III, the data from", "Confidence": 0.9808, "X1": 0.06283, "Y1": 0.7482, "X2": 0.45288, "Y2": 0.748, "X3": 0.45288, "Y3": 0.7618, "X4": 0.06283, "Y4": 0.7618, "page": 0}, {"Word": "used for the tobacco analysis as outlined in Figure 1.", "Confidence": 0.9823, "X1": 0.48822, "Y1": 0.7452, "X2": 0.87958, "Y2": 0.745, "X3": 0.87958, "Y3": 0.7588, "X4": 0.48822, "Y4": 0.7608, "page": 0}, {"Word": "these 14 tobacco products support the concept that NPRO", "Confidence": 0.94, "X1": 0.06152, "Y1": 0.7612, "X2": 0.45288, "Y2": 0.761, "X3": 0.45288, "Y3": 0.7748, "X4": 0.06152, "Y4": 0.7748, "page": 0}, {"Word": "Despite repeated analyses we were unable to detect NPRO ..", "Confidence": 0.9422, "X1": 0.4856, "Y1": 0.7582, "X2": 0.88482, "Y2": 0.758, "X3": 0.88482, "Y3": 0.7708, "X4": 0.4856, "Y4": 0.7738, "page": 0}, {"Word": "can serve as an indicator for the formation of N'-nitroso-", "Confidence": 0.9723, "X1": 0.06283, "Y1": 0.7742, "X2": 0.45288, "Y2": 0.774, "X3": 0.45288, "Y3": 0.7868, "X4": 0.06283, "Y4": 0.7888, "page": 0}, {"Word": "in tobacco smoke. When 5 mg of proline or 5 mg of NPRO", "Confidence": 0.92231, "X1": 0.48691, "Y1": 0.7702, "X2": 0.87958, "Y2": 0.77, "X3": 0.87958, "Y3": 0.7838, "X4": 0.48691, "Y4": 0.7858, "page": 0}, {"Word": "was added to the 62-mm cigarette column with a micro-", "Confidence": 0.9763, "X1": 0.48691, "Y1": 0.7852, "X2": 0.88482, "Y2": 0.785, "X3": 0.88482, "Y3": 0.7978, "X4": 0.48691, "Y4": 0.7998, "page": 0}, {"Word": "nornicotine (12 = 0.961) and of TSNA (+2 = 0.899). These", "Confidence": 0.82936, "X1": 0.06021, "Y1": 0.7862, "X2": 0.45419, "Y2": 0.786, "X3": 0.45419, "Y3": 0.7998, "X4": 0.06021, "Y4": 0.8008, "page": 0}, {"Word": "statistically significant correlations are not much further", "Confidence": 0.97429, "X1": 0.06152, "Y1": 0.8002, "X2": 0.45288, "Y2": 0.8, "X3": 0.45288, "Y3": 0.8128, "X4": 0.06152, "Y4": 0.8138, "page": 0}, {"Word": "syringe and when the mainstream smoke of 100 cigarettes", "Confidence": 0.99111, "X1": 0.48691, "Y1": 0.7972, "X2": 0.88089, "Y2": 0.797, "X3": 0.88089, "Y3": 0.8108, "X4": 0.48691, "Y4": 0.8128, "page": 0}, {"Word": "enhanced by adding nitrate as a second variable (2 = 0.966", "Confidence": 0.91227, "X1": 0.06283, "Y1": 0.8122, "X2": 0.45288, "Y2": 0.812, "X3": 0.45288, "Y3": 0.8258, "X4": 0.06283, "Y4": 0.8278, "page": 0}, {"Word": "spiked with proline or NPRO was analyzed, we found that", "Confidence": 0.9881, "X1": 0.48822, "Y1": 0.8102, "X2": 0.88089, "Y2": 0.81, "X3": 0.88089, "Y3": 0.8238, "X4": 0.48822, "Y4": 0.8258, "page": 0}, {"Word": "PRO and especially NPRO serve'as precursor for N-", "Confidence": 0.8785, "X1": 0.48691, "Y1": 0.8232, "X2": 0.87958, "Y2": 0.823, "X3": 0.87958, "Y3": 0.8368, "X4": 0.48691, "Y4": 0.8378, "page": 0}, {"Word": "and 0.918) or proline (+2 = 0.962 and 0.903) or both vari-", "Confidence": 0.91058, "X1": 0.06283, "Y1": 0.8252, "X2": 0.45419, "Y2": 0.825, "X3": 0.45419, "Y3": 0.8388, "X4": 0.06283, "Y4": 0.8398, "page": 0}, {"Word": "ables (12 == 0.966 and 0.918).", "Confidence": 0.77533, "X1": 0.06545, "Y1": 0.8382, "X2": 0.26702, "Y2": 0.838, "X3": 0.26702, "Y3": 0.8508, "X4": 0.06545, "Y4": 0.8508, "page": 0}, {"Word": "nitrosopyrrolidine in the smoke (Table IV). \"Upon spiking", "Confidence": 0.924, "X1": 0.48953, "Y1": 0.8362, "X2": 0.8822, "Y2": 0.836, "X3": 0.8822, "Y3": 0.8498, "X4": 0.48953, "Y4": 0.8518, "page": 0}, {"Word": "Fine-Cut Snuff. In agreement with earlier findings", "Confidence": 0.94371, "X1": 0.0733, "Y1": 0.8502, "X2": 0.45812, "Y2": 0.85, "X3": 0.45812, "Y3": 0.8648, "X4": 0.0733, "Y4": 0.8648, "page": 0}, {"Word": "of the cigarettes with 5 mg of NPRO we found 7140 ng of", "Confidence": 0.98985, "X1": 0.48822, "Y1": 0.8492, "X2": 0.87958, "Y2": 0.849, "X3": 0.87958, "Y3": 0.8618, "X4": 0.48822, "Y4": 0.8638, "page": 0}, {"Word": "(U.S. Surgeon General, 1982; Brunnemann et al ., 1982),", "Confidence": 0.97889, "X1": 0.06021, "Y1": 0.8632, "X2": 0.45681, "Y2": 0.863, "X3": 0.45681, "Y3": 0.8778, "X4": 0.06021, "Y4": 0.8778, "page": 0}, {"Word": "NPRO/cigarette in the mainstream smoke corresponding", "Confidence": 0.94383, "X1": 0.48691, "Y1": 0.8622, "X2": 0.87565, "Y2": 0.862, "X3": 0.87565, "Y3": 0.8758, "X4": 0.48691, "Y4": 0.8758, "page": 0}, {"Word": "to a transfer rate of 0.14%. Since this test cigarette con-", "Confidence": 0.98764, "X1": 0.48822, "Y1": 0.8742, "X2": 0.87827, "Y2": 0.874, "X3": 0.87827, "Y3": 0.8868, "X4": 0.48822, "Y4": 0.8888, "page": 0}, {"Word": "the highest amounts of N'-nitrosonornicotine and other", "Confidence": 0.96686, "X1": 0.06545, "Y1": 0.8752, "X2": 0.45812, "Y2": 0.875, "X3": 0.45812, "Y3": 0.8888, "X4": 0.06545, "Y4": 0.8908, "page": 0}, {"Word": "tobacco-specific N-nitrosamines are found in fine-cut snuff", "Confidence": 0.92886, "X1": 0.06152, "Y1": 0.8882, "X2": 0.4555, "Y2": 0.888, "X3": 0.4555, "Y3": 0.9018, "X4": 0.06152, "Y4": 0.9028, "page": 0}, {"Word": "tained 0.88 ppm (680 ng) of NPRO in the 62-mm tobacco", "Confidence": 0.98218, "X1": 0.48953, "Y1": 0.8872, "X2": 0.87827, "Y2": 0.887, "X3": 0.87827, "Y3": 0.8998, "X4": 0.48953, "Y4": 0.9018, "page": 0}, {"Word": "(Table D). During the processing of tobacco to this product,", "Confidence": 0.9372, "X1": 0.06414, "Y1": 0.9022, "X2": 0.4555, "Y2": 0.902, "X3": 0.4555, "Y3": 0.9158, "X4": 0.06414, "Y4": 0.9158, "page": 0}, {"Word": "column smoked, a 0.14% transfer rate would account for", "Confidence": 0.98611, "X1": 0.48822, "Y1": 0.8992, "X2": 0.87827, "Y2": 0.899, "X3": 0.87827, "Y3": 0.9118, "X4": 0.48822, "Y4": 0.9148, "page": 0}, {"Word": "0.9 ng of the nitroso compound in the smoke/cigarette.", "Confidence": 0.98989, "X1": 0.48822, "Y1": 0.9122, "X2": 0.87958, "Y2": 0.912, "X3": 0.87958, "Y3": 0.9258, "X4": 0.48822, "Y4": 0.9288, "page": 0}, {"Word": "including fire curing, in this sample about 0.07% of nico-", "Confidence": 0.9942, "X1": 0.06545, "Y1": 0.9152, "X2": 0.45419, "Y2": 0.915, "X3": 0.45419, "Y3": 0.9288, "X4": 0.06545, "Y4": 0.9298, "page": 0}, {"Word": "tine have been N-nitrosated to carcinogenic N'-nitroso-", "Confidence": 0.97543, "X1": 0.06545, "Y1": 0.9292, "X2": 0.45419, "Y2": 0.929, "X3": 0.45419, "Y3": 0.9428, "X4": 0.06545, "Y4": 0.9428, "page": 0}, {"Word": "Since this calculated amount is close to the detection limit,", "Confidence": 0.94, "X1": 0.48953, "Y1": 0.9262, "X2": 0.87958, "Y2": 0.926, "X3": 0.87958, "Y3": 0.9398, "X4": 0.48953, "Y4": 0.9418, "page": 0}, {"Word": "2021652345", "Confidence": 0.993, "X1": 0.94634, "Y1": 0.9542, "X2": 0.95157, "Y2": 0.954, "X3": 0.92277, "Y3": 0.9538, "X4": 0.91754, "Y4": 0.8068, "page": 0}], "words_data": [{"Word": "808", "Confidence": 0.641, "X1": 0.05497, "Y1": 0.0192, "X2": 0.07853, "Y2": 0.019, "X3": 0.07853, "Y3": 0.0318, "X4": 0.05497, "Y4": 0.0328, "page": 0, "Index": 0}, {"Word": "J.", "Confidence": 0.992, "X1": 0.09293, "Y1": 0.0192, "X2": 0.1034, "Y2": 0.019, "X3": 0.1034, "Y3": 0.0318, "X4": 0.09293, "Y4": 0.0318, "page": 0, "Index": 1}, {"Word": "Agric.", "Confidence": 0.885, "X1": 0.10733, "Y1": 0.0192, "X2": 0.14136, "Y2": 0.019, "X3": 0.14005, "Y3": 0.0318, "X4": 0.10602, "Y4": 0.0318, "page": 0, 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These patients excrete", "Confidence": 0.97514, "X1": 0.28373, "Y1": 0.1322, "X2": 0.6633, "Y2": 0.132, "X3": 0.6633, "Y3": 0.1458, "X4": 0.28373, "Y4": 0.1438, "page": 0}, {"Word": "normal amounts of atiocholanolone,' unlike the", "Confidence": 0.88467, "X1": 0.28373, "Y1": 0.1452, "X2": 0.66456, "Y2": 0.145, "X3": 0.66456, "Y3": 0.1588, "X4": 0.28373, "Y4": 0.1578, "page": 0}, {"Word": "patients with breast cancer who excrete both andro-", "Confidence": 0.98425, "X1": 0.28247, "Y1": 0.1582, "X2": 0.66456, "Y2": 0.158, "X3": 0.66456, "Y3": 0.1728, "X4": 0.28247, "Y4": 0.1708, "page": 0}, {"Word": "sterone and stiocholanolone in subnormal amounts.\".\u00aa", "Confidence": 0.831, "X1": 0.28373, "Y1": 0.1722, "X2": 0.66709, "Y2": 0.172, "X3": 0.66709, "Y3": 0.1858, "X4": 0.28373, "Y4": 0.1828, "page": 0}, {"Word": "The excretion of neither total 17-oxosteroids nor of", "Confidence": 0.99, "X1": 0.28373, "Y1": 0.1852, "X2": 0.66709, "Y2": 0.185, "X3": 0.66583, "Y3": 0.1978, "X4": 0.28373, "Y4": 0.1958, "page": 0}, {"Word": "17-OHc.s. was found to be of any prognostic value.", "Confidence": 0.99178, "X1": 0.28373, "Y1": 0.1992, "X2": 0.66456, "Y2": 0.199, "X3": 0.66456, "Y3": 0.2118, "X4": 0.28373, "Y4": 0.2088, "page": 0}, {"Word": "However, the 17-OHc.s./A ratio showed a higher", "Confidence": 0.95786, "X1": 0.28373, "Y1": 0.2122, "X2": 0.66456, "Y2": 0.212, "X3": 0.6633, "Y3": 0.2258, "X4": 0.28373, "Y4": 0.2218, "page": 0}, {"Word": "degree of correlation with survival than did andro-", "Confidence": 0.994, "X1": 0.28247, "Y1": 0.2252, "X2": 0.66456, "Y2": 0.225, "X3": 0.66456, "Y3": 0.2388, "X4": 0.28247, "Y4": 0.2368, "page": 0}, {"Word": "sterone by itself, and this ratio is as effective as the", "Confidence": 0.98445, "X1": 0.28121, "Y1": 0.2382, "X2": 0.66456, "Y2": 0.238, "X3": 0.66456, "Y3": 0.2518, "X4": 0.28121, "Y4": 0.2498, "page": 0}, {"Word": "discriminant in the prognosis of inoperable cancer.", "Confidence": 0.993, "X1": 0.27869, "Y1": 0.2522, "X2": 0.66583, "Y2": 0.252, "X3": 0.66583, "Y3": 0.2648, "X4": 0.27869, "Y4": 0.2618, "page": 0}, {"Word": "It is interesting that this ratio is equally effective in", "Confidence": 0.9895, "X1": 0.28247, "Y1": 0.2642, "X2": 0.66204, "Y2": 0.264, "X3": 0.66204, "Y3": 0.2788, "X4": 0.28247, "Y4": 0.2758, "page": 0}, {"Word": "discriminating between patients with inoperable", "Confidence": 0.8952, "X1": 0.28247, "Y1": 0.2782, "X2": 0.66204, "Y2": 0.278, "X3": 0.66204, "Y3": 0.2918, "X4": 0.28247, "Y4": 0.2898, "page": 0}, {"Word": "cancer and controls.\"", "Confidence": 0.88467, "X1": 0.27995, "Y1": 0.2892, "X2": 0.43632, "Y2": 0.289, "X3": 0.43632, "Y3": 0.3018, "X4": 0.27995, "Y4": 0.3028, "page": 0}, {"Word": "Previous work from this laboratory has indicated", "Confidence": 0.991, "X1": 0.29508, "Y1": 0.3032, "X2": 0.6633, "Y2": 0.303, "X3": 0.6633, "Y3": 0.3178, "X4": 0.29508, "Y4": 0.3158, "page": 0}, {"Word": "that the abnormalities in steroid excretion in patients", "Confidence": 0.96263, "X1": 0.27491, "Y1": 0.3182, "X2": 0.66456, "Y2": 0.318, "X3": 0.6633, "Y3": 0.3318, "X4": 0.27491, "Y4": 0.3298, "page": 0}, {"Word": "with lung cancer are not likely to be the effect of the", "Confidence": 0.98625, "X1": 0.28121, "Y1": 0.3312, "X2": 0.66078, "Y2": 0.331, "X3": 0.66078, "Y3": 0.3448, "X4": 0.28121, "Y4": 0.3428, "page": 0}, {"Word": "presence of the tumour, because surgical removal of", "Confidence": 0.9655, "X1": 0.27869, "Y1": 0.3442, "X2": 0.6633, "Y2": 0.344, "X3": 0.6633, "Y3": 0.3578, "X4": 0.27869, "Y4": 0.3568, "page": 0}, {"Word": "the tumour does not result in the disappearance", "Confidence": 0.98487, "X1": 0.27869, "Y1": 0.3592, "X2": 0.66204, "Y2": 0.359, "X3": 0.66204, "Y3": 0.3718, "X4": 0.27869, "Y4": 0.3688, "page": 0}, {"Word": "of these abnormalities.1 The physiological basis of", "Confidence": 0.93657, "X1": 0.27995, "Y1": 0.3702, "X2": 0.6633, "Y2": 0.37, "X3": 0.6633, "Y3": 0.3848, "X4": 0.27995, "Y4": 0.3828, "page": 0}, {"Word": "our findings is obscure.", "Confidence": 0.98325, "X1": 0.27995, "Y1": 0.3832, "X2": 0.45145, "Y2": 0.383, "X3": 0.45145, "Y3": 0.3968, "X4": 0.27995, "Y4": 0.3948, "page": 0}, {"Word": "We thank Dr. R. J. C. Cuthbert, Dr. J. Cuthbert, Dr. J. T.", "Confidence": 0.96869, "X1": 0.29508, "Y1": 0.4042, "X2": 0.66204, "Y2": 0.404, "X3": 0.66204, "Y3": 0.4178, "X4": 0.29508, "Y4": 0.4158, "page": 0}, {"Word": "Boyd, Mr. J. Hurcheson, Mr. M. A. Turner, Mr. R. A.", "Confidence": 0.946, "X1": 0.27995, "Y1": 0.4122, "X2": 0.66456, "Y2": 0.412, "X3": 0.66456, "Y3": 0.4258, "X4": 0.27995, "Y4": 0.4258, "page": 0}, {"Word": "McCluskie, and Mr. R. S. Barclay for the facilities to investigate", "Confidence": 0.94482, "X1": 0.27869, "Y1": 0.4272, "X2": 0.66204, "Y2": 0.427, "X3": 0.66204, "Y3": 0.4378, "X4": 0.27869, "Y4": 0.4358, "page": 0}, {"Word": "their patients, and Prof. T. Ferguson Rodger for his interest and", "Confidence": 0.98618, "X1": 0.27869, "Y1": 0.4362, "X2": 0.66204, "Y2": 0.436, "X3": 0.66204, "Y3": 0.4478, "X4": 0.27869, "Y4": 0.4458, "page": 0}, {"Word": "encouragement.", "Confidence": 0.686, "X1": 0.27995, "Y1": 0.4472, "X2": 0.37579, "Y2": 0.447, "X3": 0.37579, "Y3": 0.4568, "X4": 0.27995, "Y4": 0.4558, "page": 0}, {"Word": "The Medical Research Council provided", "Confidence": 0.9562, "X1": 0.37831, "Y1": 0.4472, "X2": 0.66204, "Y2": 0.447, "X3": 0.66078, "Y3": 0.4588, "X4": 0.37831, "Y4": 0.4568, "page": 0}, {"Word": "financial assistance.", "Confidence": 0.867, "X1": 0.28121, "Y1": 0.4572, "X2": 0.40353, "Y2": 0.457, "X3": 0.40353, "Y3": 0.4688, "X4": 0.27995, "Y4": 0.4678, "page": 0}, {"Word": "Requests for reprints should be addressed to L. G. S. R.", "Confidence": 0.94964, "X1": 0.2913, "Y1": 0.4672, "X2": 0.64943, "Y2": 0.467, "X3": 0.64943, "Y3": 0.4798, "X4": 0.2913, "Y4": 0.4788, "page": 0}, {"Word": "REFERENCES", "Confidence": 0.856, "X1": 0.4338, "Y1": 0.4882, "X2": 0.50694, "Y2": 0.488, "X3": 0.50694, "Y3": 0.4968, "X4": 0.4338, "Y4": 0.4968, "page": 0}, {"Word": "1. Rao, L. G. S. Lancer, 1970, il, 441.", "Confidence": 0.90144, "X1": 0.28499, "Y1": 0.5002, "X2": 0.49559, "Y2": 0.5, "X3": 0.49559, "Y3": 0.5118, "X4": 0.28499, "Y4": 0.5118, "page": 0}, {"Word": "2. Bulbrook, R. D ., Hayward, J. L ., Spicer, C. C ., Thomas, B. S.", "Confidence": 0.94144, "X1": 0.28499, "Y1": 0.5112, "X2": 0.65952, "Y2": 0.511, "X3": 0.65952, "Y3": 0.5228, "X4": 0.28499, "Y4": 0.5208, "page": 0}, {"Word": "ibid. 1962, i, 1235.", "Confidence": 0.77225, "X1": 0.30517, "Y1": 0.5192, "X2": 0.4174, "Y2": 0.519, "X3": 0.4174, "Y3": 0.5298, "X4": 0.30517, "Y4": 0.5298, "page": 0}, {"Word": "3. Bulbrook, R. D ., Hayward, J. L ., Spicer, C. C ., Thomas, B. S.", "Confidence": 0.92056, "X1": 0.28499, "Y1": 0.5292, "X2": 0.66204, "Y2": 0.529, "X3": 0.66204, "Y3": 0.5418, "X4": 0.28499, "Y4": 0.5398, "page": 0}, {"Word": "ibid. p. 1238.", "Confidence": 0.75533, "X1": 0.30391, "Y1": 0.5392, "X2": 0.38588, "Y2": 0.539, "X3": 0.38588, "Y3": 0.5498, "X4": 0.30391, "Y4": 0.5488, "page": 0}, {"Word": ". Thetnas, B. S ., Bulbrook, R. D ., Hayward, J. L. Br. med. f. 1967,", "Confidence": 0.85687, "X1": 0.29256, "Y1": 0.5482, "X2": 0.65826, "Y2": 0.548, "X3": 0.65826, "Y3": 0.5608, "X4": 0.29256, "Y4": 0.5588, "page": 0}, {"Word": "HI, 523.", "Confidence": 0.541, "X1": 0.30517, "Y1": 0.5572, "X2": 0.35435, "Y2": 0.557, "X3": 0.35435, "Y3": 0.5678, "X4": 0.30517, "Y4": 0.5678, "page": 0}, {"Word": "5. Siegel, S. in Non-parametric Statistics, p. 202, London, 1956.", "Confidence": 0.818, "X1": 0.28373, "Y1": 0.5672, "X2": 0.63556, "Y2": 0.567, "X3": 0.63556, "Y3": 0.5788, "X4": 0.28373, "Y4": 0.5768, "page": 0}, {"Word": "Addendum", "Confidence": 0.995, "X1": 0.42245, "Y1": 0.5882, "X2": 0.51324, "Y2": 0.588, "X3": 0.51324, "Y3": 0.6008, "X4": 0.42245, "Y4": 0.6008, "page": 0}, {"Word": "In 30 patients with lung tumours which were re-", "Confidence": 0.98656, "X1": 0.29256, "Y1": 0.6062, "X2": 0.65826, "Y2": 0.606, "X3": 0.65826, "Y3": 0.6198, "X4": 0.29256, "Y4": 0.6178, "page": 0}, {"Word": "sected, the mean preoperative 17-OHc.s./A ratio was", "Confidence": 0.95886, "X1": 0.27743, "Y1": 0.6202, "X2": 0.66078, "Y2": 0.62, "X3": 0.66078, "Y3": 0.6328, "X4": 0.27743, "Y4": 0.6318, "page": 0}, {"Word": "8.1 -S.D. 5.3. 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This distribution is highly significant", "Confidence": 0.97213, "X1": 0.27491, "Y1": 0.6862, "X2": 0.65826, "Y2": 0.686, "X3": 0.65826, "Y3": 0.6998, "X4": 0.27491, "Y4": 0.6988, "page": 0}, {"Word": "(x\"=13-5, 1 d.f ., P<0.001). . 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ffpv0217 | 1 | {"lines_data": [{"Word": "2", "Confidence": 0.994, "X1": 0.24, "Y1": 0.06737, "X2": 0.251, "Y2": 0.06717, "X3": 0.25, "Y3": 0.08472, "X4": 0.24, "Y4": 0.08599, "page": 0}, {"Word": "3", "Confidence": 0.988, "X1": 0.765, "Y1": 0.07244, "X2": 0.775, "Y2": 0.07224, "X3": 0.775, "Y3": 0.08599, "X4": 0.765, "Y4": 0.08472, "page": 0}, {"Word": "-10", "Confidence": 0.958, "X1": 0.146, "Y1": 0.10033, "X2": 0.164, "Y2": 0.10013, "X3": 0.164, "Y3": 0.11133, "X4": 0.146, "Y4": 0.11133, "page": 0}, {"Word": "Androsterone, by itself, showed a significant correlation", "Confidence": 0.96057, "X1": 0.627, "Y1": 0.10159, "X2": 0.916, "Y2": 0.10139, "X3": 0.916, "Y3": 0.1164, "X4": 0.627, "Y4": 0.1164, "page": 0}, {"Word": "with survival. The lower the excretion of this steroid,", "Confidence": 0.98778, "X1": 0.627, "Y1": 0.11807, "X2": 0.915, "Y2": 0.11787, "X3": 0.915, "Y3": 0.13415, "X4": 0.627, "Y4": 0.13288, "page": 0}, {"Word": "-8", "Confidence": 0.911, "X1": 0.149, "Y1": 0.14088, "X2": 0.16, "Y2": 0.14068, "X3": 0.159, "Y3": 0.15062, "X4": 0.149, "Y4": 0.15062, "page": 0}, {"Word": "the shorter was the survival-time. Atiocholanolone,", "Confidence": 0.952, "X1": 0.623, "Y1": 0.13455, "X2": 0.916, "Y2": 0.13435, "X3": 0.916, "Y3": 0.15316, "X4": 0.623, "Y4": 0.15189, "page": 0}, {"Word": "DISCRIMINANT SCORES", "Confidence": 0.8445, "X1": 0.132, "Y1": 0.17384, "X2": 0.133, "Y2": 0.17364, "X3": 0.143, "Y3": 0.17344, "X4": 0.142, "Y4": 0.31919, "page": 0}, {"Word": "on the other hand, was of no such prognostic value,", "Confidence": 0.9828, "X1": 0.625, "Y1": 0.15356, "X2": 0.915, "Y2": 0.15336, "X3": 0.915, "Y3": 0.1709, "X4": 0.625, "Y4": 0.16964, "page": 0}, {"Word": "nor was the 17-OHc.s./E ratio. 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Therefore, it seems", "Confidence": 0.98743, "X1": 0.623, "Y1": 0.35001, "X2": 0.915, "Y2": 0.34981, "X3": 0.915, "Y3": 0.36735, "X4": 0.623, "Y4": 0.36609, "page": 0}, {"Word": "that the lesser the degree of abnormality in the excre-", "Confidence": 0.9634, "X1": 0.626, "Y1": 0.36775, "X2": 0.915, "Y2": 0.36755, "X3": 0.915, "Y3": 0.3851, "X4": 0.626, "Y4": 0.38256, "page": 0}, {"Word": "tion of androsterone and other urinary steroids", "Confidence": 0.99471, "X1": 0.625, "Y1": 0.3855, "X2": 0.913, "Y2": 0.3853, "X3": 0.913, "Y3": 0.40284, "X4": 0.625, "Y4": 0.40157, "page": 0}, {"Word": "5", "Confidence": 0.649, "X1": 0.187, "Y1": 0.39564, "X2": 0.198, "Y2": 0.39544, "X3": 0.197, "Y3": 0.40918, "X4": 0.187, "Y4": 0.40791, "page": 0}, {"Word": "10", "Confidence": 0.948, "X1": 0.199, "Y1": 0.3969, "X2": 0.228, "Y2": 0.3967, "X3": 0.228, "Y3": 0.40918, "X4": 0.198, "Y4": 0.41045, "page": 0}, {"Word": "15 20 25 . 30", "Confidence": 0.9192, "X1": 0.229, "Y1": 0.3969, "X2": 0.35, "Y2": 0.3967, "X3": 0.35, "Y3": 0.41045, "X4": 0.229, "Y4": 0.40918, "page": 0}, {"Word": "SURVIVAL (months)", "Confidence": 0.796, "X1": 0.204, "Y1": 0.41085, "X2": 0.303, "Y2": 0.41065, "X3": 0.303, "Y3": 0.42566, "X4": 0.204, "Y4": 0.42439, "page": 0}, {"Word": "compared with controls, the better is the prognosis", "Confidence": 0.99475, "X1": 0.622, "Y1": 0.40197, "X2": 0.915, "Y2": 0.40177, "X3": 0.915, "Y3": 0.42185, "X4": 0.622, "Y4": 0.42059, "page": 0}, {"Word": "in patients with inoperable lung cancer.", "Confidence": 0.9805, "X1": 0.625, "Y1": 0.42099, "X2": 0.836, "Y2": 0.42079, "X3": 0.836, "Y3": 0.43706, "X4": 0.625, "Y4": 0.43706, "page": 0}, {"Word": "Fig. 1-Correlation of survival-time and discriminant function", "Confidence": 0.79429, "X1": 0.097, "Y1": 0.42859, "X2": 0.386, "Y2": 0.42839, "X3": 0.386, "Y3": 0.44213, "X4": 0.097, "Y4": 0.44086, "page": 0}, {"Word": "scores in patients with inoperable lung cancer.", "Confidence": 0.92771, "X1": 0.108, "Y1": 0.44126, "X2": 0.317, "Y2": 0.44106, "X3": 0.317, "Y3": 0.45481, "X4": 0.108, "Y4": 0.45354, "page": 0}, {"Word": "Steroid discriminants have been shown. to be of", "Confidence": 0.96675, "X1": 0.637, "Y1": 0.43746, "X2": 0.916, "Y2": 0.43726, "X3": 0.916, "Y3": 0.45607, "X4": 0.637, "Y4": 0.45481, "page": 0}, {"Word": "prognostic value in patients with breast cancer.\"-", "Confidence": 0.93286, "X1": 0.622, "Y1": 0.45521, "X2": 0.916, "Y2": 0.45501, "X3": 0.916, "Y3": 0.47382, "X4": 0.622, "Y4": 0.47382, "page": 0}, {"Word": "Patients and Methods", "Confidence": 0.99433, "X1": 0.183, "Y1": 0.46661, "X2": 0.308, "Y2": 0.46641, "X3": 0.308, "Y3": 0.48269, "X4": 0.183, "Y4": 0.48269, "page": 0}, {"Word": "These discriminants are based on the excretion of", "Confidence": 0.9955, "X1": 0.623, "Y1": 0.47295, "X2": 0.914, "Y2": 0.47275, "X3": 0.914, "Y3": 0.49156, "X4": 0.623, "Y4": 0.48903, "page": 0}, {"Word": "The inoperable-cancer patients and laboratory methods", "Confidence": 0.97717, "X1": 0.112, "Y1": 0.48816, "X2": 0.39, "Y2": 0.48796, "X3": 0.39, "Y3": 0.50424, "X4": 0.112, "Y4": 0.50424, "page": 0}, {"Word": "17-OHc.s. and \u00e6tiocholanolone, although 17-OHc.s.", "Confidence": 0.8226, "X1": 0.624, "Y1": 0.48943, "X2": 0.913, "Y2": 0.48923, "X3": 0.913, "Y3": 0.50931, "X4": 0.624, "Y4": 0.50804, "page": 0}, {"Word": "were the same as those described earlier.\" The prognosis", "Confidence": 0.92367, "X1": 0.102, "Y1": 0.50337, "X2": 0.39, "Y2": 0.50317, "X3": 0.39, "Y3": 0.51945, "X4": 0.102, "Y4": 0.52071, "page": 0}, {"Word": "and androsterone were shown to be equally effective", "Confidence": 0.97637, "X1": 0.625, "Y1": 0.50844, "X2": 0.913, "Y2": 0.50824, "X3": 0.913, "Y3": 0.52578, "X4": 0.625, "Y4": 0.52578, "page": 0}, {"Word": "has been assessed as the period of survival after the date of", "Confidence": 0.98217, "X1": 0.101, "Y1": 0.51985, "X2": 0.391, "Y2": 0.51965, "X3": 0.391, "Y3": 0.53465, "X4": 0.101, "Y4": 0.53465, "page": 0}, {"Word": "for this purpose.\" In our serics androsterone", "Confidence": 0.87671, "X1": 0.625, "Y1": 0.52618, "X2": 0.914, "Y2": 0.52598, "X3": 0.914, "Y3": 0.54353, "X4": 0.625, "Y4": 0.54226, "page": 0}, {"Word": "first diagnosis. The patients included in this study have", "Confidence": 0.97667, "X1": 0.102, "Y1": 0.53505, "X2": 0.39, "Y2": 0.53485, "X3": 0.39, "Y3": 0.55113, "X4": 0.102, "Y4": 0.55113, "page": 0}, {"Word": "been followed' up for at least 1 year after diagnosis except", "Confidence": 0.94745, "X1": 0.102, "Y1": 0.55153, "X2": 0.39, "Y2": 0.55133, "X3": 0.39, "Y3": 0.56634, "X4": 0.102, "Y4": 0.56634, "page": 0}, {"Word": "excretion, but not atiocholanolone excretion, was", "Confidence": 0.8225, "X1": 0.624, "Y1": 0.54393, "X2": 0.912, "Y2": 0.54373, "X3": 0.912, "Y3": 0.56, "X4": 0.624, "Y4": 0.55874, "page": 0}, {"Word": "those who died within this period. Only six patients are", "Confidence": 0.9813, "X1": 0.102, "Y1": 0.56674, "X2": 0.39, "Y2": 0.56654, "X3": 0.39, "Y3": 0.58155, "X4": 0.102, "Y4": 0.58155, "page": 0}, {"Word": "significantly correlated with survival-time in patients", "Confidence": 0.981, "X1": 0.624, "Y1": 0.5604, "X2": 0.912, "Y2": 0.5602, "X3": 0.912, "Y3": 0.57901, "X4": 0.624, "Y4": 0.57901, "page": 0}, {"Word": "100", "Confidence": 0.665, "X1": 0.673, "Y1": 0.57941, "X2": 0.695, "Y2": 0.57921, "X3": 0.695, "Y3": 0.59422, "X4": 0.673, "Y4": 0.59422, "page": 0}, {"Word": "still alive for whom the diagnosis has been known for over", "Confidence": 0.98627, "X1": 0.102, "Y1": 0.58195, "X2": 0.39, "Y2": 0.58175, "X3": 0.39, "Y3": 0.59803, "X4": 0.102, "Y4": 0.59803, "page": 0}, {"Word": "a year. All these patients received radiotherapy or", "Confidence": 0.84637, "X1": 0.102, "Y1": 0.59843, "X2": 0.39, "Y2": 0.59823, "X3": 0.39, "Y3": 0.61323, "X4": 0.102, "Y4": 0.6145, "page": 0}, {"Word": "80", "Confidence": 0.932, "X1": 0.677, "Y1": 0.59716, "X2": 0.695, "Y2": 0.59696, "X3": 0.695, "Y3": 0.60817, "X4": 0.677, "Y4": 0.60943, "page": 0}, {"Word": "chemotherapy with cyclophosphamide.\"", "Confidence": 0.628, "X1": 0.102, "Y1": 0.61237, "X2": 0.296, "Y2": 0.61217, "X3": 0.296, "Y3": 0.62718, "X4": 0.102, "Y4": 0.63098, "page": 0}, {"Word": "60", "Confidence": 0.983, "X1": 0.677, "Y1": 0.62124, "X2": 0.689, "Y2": 0.62104, "X3": 0.689, "Y3": 0.63225, "X4": 0.676, "Y4": 0.63225, "page": 0}, {"Word": "The period of survival in months has been correlated.", "Confidence": 0.97833, "X1": 0.114, "Y1": 0.62884, "X2": 0.393, "Y2": 0.62864, "X3": 0.393, "Y3": 0.64492, "X4": 0.114, "Y4": 0.64492, "page": 0}, {"Word": "IT-O H GR. IANDROSTERONE RATIO", "Confidence": 0.683, "X1": 0.662, "Y1": 0.65546, "X2": 0.662, "Y2": 0.65526, "X3": 0.672, "Y3": 0.65506, "X4": 0.673, "Y4": 0.85658, "page": 0}, {"Word": "with the steroid-excretion values. 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How would", "Confidence": 0.99436, "X1": 0.112, "Y1": 0.2472, "X2": 0.9344, "Y2": 0.247, "X3": 0.9344, "Y3": 0.2588, "X4": 0.112, "Y4": 0.2608, "page": 0}, {"Word": "you describe it to your friend? (PROBE:) How else would you describe this", "Confidence": 0.99354, "X1": 0.1104, "Y1": 0.2592, "X2": 0.9008, "Y2": 0.259, "X3": 0.9008, "Y3": 0.2728, "X4": 0.1104, "Y4": 0.2728, "page": 0}, {"Word": "cigarette? 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Now I'd like you to think about the taste of Rio. Based on the ad, would", "Confidence": 0.99388, "X1": 0.0448, "Y1": 0.4362, "X2": 0.88, "Y2": 0.436, "X3": 0.88, "Y3": 0.4508, "X4": 0.0448, "Y4": 0.4518, "page": 0}, {"Word": "you say that Rio would be ... 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And what about the tar level? Would you say that Rio would be ...", "Confidence": 0.95393, "X1": 0.0432, "Y1": 0.5732, "X2": 0.7968, "Y2": 0.573, "X3": 0.7968, "Y3": 0.5868, "X4": 0.0432, "Y4": 0.5878, "page": 0}, {"Word": "(READ LIST)?", "Confidence": 0.974, "X1": 0.8048, "Y1": 0.5712, "X2": 0.9392, "Y2": 0.571, "X3": 0.9392, "Y3": 0.5878, "X4": 0.8048, "Y4": 0.5878, "page": 0}, {"Word": "Very low in tar", "Confidence": 0.96575, "X1": 0.3056, "Y1": 0.5982, "X2": 0.4672, "Y2": 0.598, "X3": 0.4672, "Y3": 0.6108, "X4": 0.3056, "Y4": 0.6108, "page": 0}, {"Word": "40( )-1", "Confidence": 0.996, "X1": 0.6256, "Y1": 0.5972, "X2": 0.7312, "Y2": 0.597, "X3": 0.7312, "Y3": 0.6118, "X4": 0.6256, "Y4": 0.6118, "page": 0}, {"Word": "Low in tar.", "Confidence": 0.98333, "X1": 0.3056, "Y1": 0.6162, "X2": 0.4256, "Y2": 0.616, "X3": 0.4256, "Y3": 0.6288, "X4": 0.3056, "Y4": 0.6288, "page": 0}, {"Word": "( )-2", "Confidence": 0.9785, "X1": 0.6512, "Y1": 0.6152, "X2": 0.7248, "Y2": 0.615, "X3": 0.7248, "Y3": 0.6298, "X4": 0.6512, "Y4": 0.6298, "page": 0}, {"Word": "About average.", "Confidence": 0.9935, "X1": 0.3056, "Y1": 0.6362, "X2": 0.4496, "Y2": 0.636, "X3": 0.4496, "Y3": 0.6488, "X4": 0.3056, "Y4": 0.6468, "page": 0}, {"Word": "( )-3", "Confidence": 0.987, "X1": 0.6496, "Y1": 0.6332, "X2": 0.728, "Y2": 0.633, "X3": 0.7296, "Y3": 0.6488, "X4": 0.6496, "Y4": 0.6498, "page": 0}, {"Word": "Slightly above average, or.", "Confidence": 0.97225, "X1": 0.3056, "Y1": 0.6532, "X2": 0.5888, "Y2": 0.653, "X3": 0.5888, "Y3": 0.6678, "X4": 0.3056, "Y4": 0.6668, "page": 0}, {"Word": "( )-4", "Confidence": 0.9915, "X1": 0.6496, "Y1": 0.6522, "X2": 0.7296, "Y2": 0.652, "X3": 0.7296, "Y3": 0.6678, "X4": 0.6496, "Y4": 0.6668, "page": 0}, {"Word": "High in tar.", "Confidence": 0.991, "X1": 0.3056, "Y1": 0.6702, "X2": 0.4336, "Y2": 0.67, "X3": 0.4336, "Y3": 0.6838, "X4": 0.3056, "Y4": 0.6838, "page": 0}, {"Word": "( )-5", "Confidence": 0.9855, "X1": 0.6512, "Y1": 0.6692, "X2": 0.7312, "Y2": 0.669, "X3": 0.7312, "Y3": 0.6838, "X4": 0.6512, "Y4": 0.6858, "page": 0}, {"Word": "24. I would like to give you a pack of Rio cigarettes for free -- for you to try", "Confidence": 0.98337, "X1": 0.0432, "Y1": 0.6962, "X2": 0.9088, "Y2": 0.696, "X3": 0.9088, "Y3": 0.7108, "X4": 0.0432, "Y4": 0.7108, "page": 0}, {"Word": "at your convenience. Then after you've tried them, I would like to call you on", "Confidence": 0.98967, "X1": 0.1056, "Y1": 0.7082, "X2": 0.936, "Y2": 0.708, "X3": 0.936, "Y3": 0.7218, "X4": 0.1056, "Y4": 0.7228, "page": 0}, {"Word": "the telephone to see what you think of them. Would you be willing to do this?", "Confidence": 0.99569, "X1": 0.1056, "Y1": 0.7212, "X2": 0.9312, "Y2": 0.721, "X3": 0.9312, "Y3": 0.7338, "X4": 0.1056, "Y4": 0.7338, "page": 0}, {"Word": "Yes ...", "Confidence": 0.985, "X1": 0.2528, "Y1": 0.7452, "X2": 0.336, "Y2": 0.745, "X3": 0.336, "Y3": 0.7598, "X4": 0.2528, "Y4": 0.7598, "page": 0}, {"Word": "(.)", "Confidence": 0.727, "X1": 0.3456, "Y1": 0.7452, "X2": 0.4016, "Y2": 0.745, "X3": 0.4016, "Y3": 0.7608, "X4": 0.3456, "Y4": 0.7598, "page": 0}, {"Word": "No. ..", "Confidence": 0.8, "X1": 0.6176, "Y1": 0.7482, "X2": 0.6896, "Y2": 0.748, "X3": 0.688, "Y3": 0.7608, "X4": 0.6176, "Y4": 0.7578, "page": 0}, {"Word": "()", "Confidence": 0.724, "X1": 0.6992, "Y1": 0.7452, "X2": 0.7584, "Y2": 0.745, "X3": 0.7584, "Y3": 0.7588, "X4": 0.6976, "Y4": 0.7578, "page": 0}, {"Word": "(THANK AND TERMINATE)", "Confidence": 0.98133, "X1": 0.64, "Y1": 0.7572, "X2": 0.8624, "Y2": 0.757, "X3": 0.8624, "Y3": 0.7718, "X4": 0.64, "Y4": 0.7718, "page": 0}, 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Int J", "Confidence": 0.4101, "X1": 0.52042, "Y1": 0.2982, "X2": 0.83926, "Y2": 0.298, "X3": 0.83926, "Y3": 0.3108, "X4": 0.52042, "Y4": 0.3118, "page": 0}, {"Word": "We thank Dr RF Heller, assistant director HDPP. for", "Confidence": 0.85367, "X1": 0.14493, "Y1": 0.3122, "X2": 0.48353, "Y2": 0.312, "X3": 0.48353, "Y3": 0.3268, "X4": 0.14493, "Y4": 0.3268, "page": 0}, {"Word": "Cancer 1984:33:569-74.", "Confidence": 0.2515, "X1": 0.51779, "Y1": 0.3102, "X2": 0.66535, "Y2": 0.31, "X3": 0.66535, "Y3": 0.3208, "X4": 0.51779, "Y4": 0.3208, "page": 0}, {"Word": "allowing us to resurvey meu in that study, Professor", "Confidence": 0.69833, "X1": 0.14229, "Y1": 0.3252, "X2": 0.48353, "Y2": 0.325, "X3": 0.48353, "Y3": 0.3378, "X4": 0.14229, "Y4": 0.3388, "page": 0}, {"Word": "17 Holaville GW. Biggs HW. Establishing smoking habits", "Confidence": 0.61525, "X1": 0.49934, "Y1": 0.3212, "X2": 0.84321, "Y2": 0.321, "X3": 0.84321, "Y3": 0.3348, "X4": 0.49934, "Y4": 0.3328, "page": 0}, {"Word": "in retrospect. Statirrician 1967:14:23-4].", "Confidence": 0.60075, "X1": 0.51647, "Y1": 0.3322, "X2": 0.75231, "Y2": 0.332, "X3": 0.75231, "Y3": 0.3428, "X4": 0.51647, "Y4": 0.3438, "page": 0}, {"Word": "Holland and Mr Peter Les for their advice and crit-", "Confidence": 0.7785, "X1": 0.14493, "Y1": 0.3382, "X2": 0.48485, "Y2": 0.338, "X3": 0.48485, "Y3": 0.3508, "X4": 0.14493, "Y4": 0.3508, "page": 0}, {"Word": "18 Fletcher C. Peto R. Ticker C. Spelzer FE. The aanval", "Confidence": 0.59218, "X1": 0.49802, "Y1": 0.3432, "X2": 0.84058, "Y2": 0.343, "X3": 0.84058, "Y3": 0.3548, "X4": 0.49802, "Y4": 0.3548, "page": 0}, {"Word": "icism and Mrs L Clarke for word processing the", "Confidence": 0.81733, "X1": 0.14361, "Y1": 0.3512, "X2": 0.48485, "Y2": 0.351, "X3": 0.48485, "Y3": 0.3638, "X4": 0.14361, "Y4": 0.3638, "page": 0}, {"Word": "history of chronic bronchitis avil emphysema. Oxford:", "Confidence": 0.45629, "X1": 0.52042, "Y1": 0.3552, "X2": 0.83926, "Y2": 0.355, "X3": 0.83926, "Y3": 0.3658, "X4": 0.52042, "Y4": 0.3668, "page": 0}, {"Word": "manuscript. The study was funded by the Tobacco", "Confidence": 0.789, "X1": 0.14229, "Y1": 0.3632, "X2": 0.48353, "Y2": 0.363, "X3": 0.48353, "Y3": 0.3758, "X4": 0.14229, "Y4": 0.3758, "page": 0}, {"Word": "Oxford University Press, 1976.", "Confidence": 0.5755, "X1": 0.51647, "Y1": 0.3642, "X2": 0.70619, "Y2": 0.364, "X3": 0.70619, "Y3": 0.3768, "X4": 0.51647, "Y4": 0.3748, "page": 0}, {"Word": "Products Research Trust.", "Confidence": 0.794, "X1": 0.14493, "Y1": 0.3752, "X2": 0.31621, "Y2": 0.375, "X3": 0.31621, "Y3": 0.3878, "X4": 0.14493, "Y4": 0.3878, "page": 0}, {"Word": "19 Rose G. Heller RF. Tunstall Pados H. Christie O. Heart", "Confidence": 0.58664, "X1": 0.50066, "Y1": 0.3752, "X2": 0.84058, "Y2": 0.375, "X3": 0.84058, "Y3": 0.3878, "X4": 0.50066, "Y4": 0.3868, "page": 0}, {"Word": "disease prevention project a modomaised controlled trial", "Confidence": 0.533, "X1": 0.52042, "Y1": 0.3872, "X2": 0.84058, "Y2": 0.387, "X3": 0.84058, "Y3": 0.3968, "X4": 0.52042, "Y4": 0.3968, "page": 0}, {"Word": "20 Peach H, Ellard GA. Hayward D. Morria RW, Shah D.", "Confidence": 0.77173, "X1": 0.49934, "Y1": 0.4062, "X2": 0.84058, "Y2": 0.406, "X3": 0.84058, "Y3": 0.4178, "X4": 0.49934, "Y4": 0.4178, "page": 0}, {"Word": "in industry. Br Med J 1980-1:747-51.", "Confidence": 0.53667, "X1": 0.51779, "Y1": 0.3952, "X2": 0.73518, "Y2": 0.395, "X3": 0.73518, "Y3": 0.4088, "X4": 0.51779, "Y4": 0.4088, "page": 0}, {"Word": "Referencia", "Confidence": 0.606, "X1": 0.14361, "Y1": 0.4072, "X2": 0.21607, "Y2": 0.407, "X3": 0.21607, "Y3": 0.4218, "X4": 0.14361, "Y4": 0.4208, "page": 0}, {"Word": "A madochised controlled trial of low versus middle uur", "Confidence": 0.70533, "X1": 0.5191, "Y1": 0.4182, "X2": 0.8419, "Y2": 0.418, "X3": 0.8419, "Y3": 0.4308, "X4": 0.51779, "Y4": 0.4288, "page": 0}, {"Word": "\"I Wyoder EL, Mabuchi K, Beartin ILJ. The epidemiology", "Confidence": 0.46711, "X1": 0.14625, "Y1": 0.4302, "X2": 0.48617, "Y2": 0.43, "X3": 0.48617, "Y3": 0.4448, "X4": 0.14625, "Y4": 0.4448, "page": 0}, {"Word": "apimite en respiratory symptoms-4 feasibility rudy.", "Confidence": 0.32717, "X1": 0.52042, "Y1": 0.4282, "X2": 0.84321, "Y2": 0.428, "X3": 0.84321, "Y3": 0.4398, "X4": 0.52042, "Y4": 0.4398, "page": 0}, {"Word": "of lung cancer, mocat trends. JAMA 1970:213-2251-4.", "Confidence": 0.37657, "X1": 0.15415, "Y1": 0.4402, "X2": 0.47826, "Y2": 0.44, "X3": 0.47826, "Y3": 0.4528, "X4": 0.15415, "Y4": 0.4548, "page": 0}, {"Word": "In: Tobacco: a major issue. (Proceedings of International", "Confidence": 0.4885, "X1": 0.51647, "Y1": 0.4382, "X2": 0.8419, "Y2": 0.438, "X3": 0.8419, "Y3": 0.4488, "X4": 0.51647, "Y4": 0.4488, "page": 0}, {"Word": "2 Rimington J. Phlegm and Allers, Ar Med / 1972:5-162-4.", "Confidence": 0.499, "X1": 0.1502, "Y1": 0.4512, "X2": 0.48221, "Y2": 0.451, "X3": 0.48221, "Y3": 0.4638, "X4": 0.1502, "Y4": 0.4638, "page": 0}, {"Word": "Meeting on Cancer Control and Prevention, Moscow,", "Confidence": 0.72529, "X1": 0.5191, "Y1": 0.4502, "X2": 0.8419, "Y2": 0.45, "X3": 0.8419, "Y3": 0.4608, "X4": 0.5191, "Y4": 0.4588, "page": 0}, {"Word": "1 Higcabouse T, Clark TIH. Shipley MJ. Rose G. Lang", "Confidence": 0.5515, "X1": 0.15283, "Y1": 0.4642, "X2": 0.48221, "Y2": 0.464, "X3": 0.48221, "Y3": 0.4758, "X4": 0.15283, "Y4": 0.4758, "page": 0}, {"Word": "1983) Lyon: LARC Scientide Publications (in press).", "Confidence": 0.51614, "X1": 0.52174, "Y1": 0.4592, "X2": 0.82609, "Y2": 0.459, "X3": 0.82609, "Y3": 0.4738, "X4": 0.52174, "Y4": 0.4708, "page": 0}, {"Word": "function and symptoms of cigarette smokers related to", "Confidence": 0.957, "X1": 0.16337, "Y1": 0.4742, "X2": 0.48221, "Y2": 0.474, "X3": 0.48221, "Y3": 0.4868, "X4": 0.16337, "Y4": 0.4868, "page": 0}, {"Word": "tar yield tad number of dearetes smoked. Lancet", "Confidence": 0.479, "X1": 0.16337, "Y1": 0.4852, "X2": 0.48353, "Y2": 0.485, "X3": 0.48353, "Y3": 0.4988, "X4": 0.16337, "Y4": 0.4978, "page": 0}, {"Word": "1980-1:409-12", "Confidence": 0.393, "X1": 0.16469, "Y1": 0.4962, "X2": 0.25428, "Y2": 0.496, "X3": 0.25428, "Y3": 0.5078, "X4": 0.16469, "Y4": 0.5078, "page": 0}, {"Word": "Appendix", "Confidence": 0.605, "X1": 0.50329, "Y1": 0.5002, "X2": 0.56126, "Y2": 0.5, "X3": 0.56126, "Y3": 0.5128, "X4": 0.50329, "Y4": 0.5128, "page": 0}, {"Word": "Beck CI, Doyle CA, Schachter EN, Smoking zad lung", "Confidence": 0.58178, "X1": 0.16206, "Y1": 0.5072, "X2": 0.48617, "Y2": 0.507, "X3": 0.48617, "Y3": 0.5198, "X4": 0.16206, "Y4": 0.5198, "page": 0}, {"Word": "function. Am Rey Respir Di 1981:123:149-35.", "Confidence": 0.37067, "X1": 0.16469, "Y1": 0.5182, "X2": 0.43083, "Y2": 0.518, "X3": 0.43215, "Y3": 0.5308, "X4": 0.16469, "Y4": 0.5308, "page": 0}, {"Word": "Cigarette pos speciled", "Confidence": 0.26567, "X1": 0.50329, "Y1": 0.5222, "X2": 0.62451, "Y2": 0.522, "X3": 0.62451, "Y3": 0.5328, "X4": 0.50329, "Y4": 0.5318, "page": 0}, {"Word": "Starsof", "Confidence": 0.568, "X1": 0.67984, "Y1": 0.5232, "X2": 0.72464, "Y2": 0.523, "X3": 0.72464, "Y3": 0.5328, "X4": 0.67984, "Y4": 0.5318, "page": 0}, {"Word": "! Hi\u00e7enbocum T. Shipley MJ. Rose G. Cigarettes, lung", "Confidence": 0.51367, "X1": 0.15415, "Y1": 0.5292, "X2": 0.48485, "Y2": 0.529, "X3": 0.48485, "Y3": 0.5418, "X4": 0.15415, "Y4": 0.5408, "page": 0}, {"Word": "Ci\u00f3n dipped", "Confidence": 0.0765, "X1": 0.50329, "Y1": 0.5322, "X2": 0.57576, "Y2": 0.532, "X3": 0.57576, "Y3": 0.5428, "X4": 0.50329, "Y4": 0.5418, "page": 0}, {"Word": "Woodbine", "Confidence": 0.61, "X1": 0.68379, "Y1": 0.5342, "X2": 0.74704, "Y2": 0.534, "X3": 0.74572, "Y3": 0.5428, "X4": 0.68379, "Y4": 0.5408, "page": 0}, {"Word": "accer. sad coronary heart disease the effects of", "Confidence": 0.47687, "X1": 0.16337, "Y1": 0.5392, "X2": 0.48353, "Y2": 0.539, "X3": 0.48353, "Y3": 0.5508, "X4": 0.16337, "Y4": 0.5528, "page": 0}, {"Word": "Capstan", "Confidence": 0.332, "X1": 0.50593, "Y1": 0.5422, "X2": 0.54809, "Y2": 0.542, "X3": 0.54809, "Y3": 0.5528, "X4": 0.50593, "Y4": 0.5528, "page": 0}, {"Word": "Souon and Hedresd", "Confidence": 0.31033, "X1": 0.68116, "Y1": 0.5442, "X2": 0.7892, "Y2": 0.544, "X3": 0.7892, "Y3": 0.5528, "X4": 0.68116, "Y4": 0.5528, "page": 0}, {"Word": "inhalation and tar yield. J Epidemiol Commun Health", "Confidence": 0.53925, "X1": 0.16337, "Y1": 0.5502, "X2": 0.48485, "Y2": 0.55, "X3": 0.48485, "Y3": 0.5628, "X4": 0.16337, "Y4": 0.5638, "page": 0}, {"Word": "Conquiste", "Confidence": 0.053, "X1": 0.50593, "Y1": 0.5542, "X2": 0.55995, "Y2": 0.554, "X3": 0.55863, "Y3": 0.5638, "X4": 0.50593, "Y4": 0.5628, "page": 0}, {"Word": "1982-34113-1.", "Confidence": 0.545, "X1": 0.16996, "Y1": 0.5622, "X2": 0.25955, "Y2": 0.562, "X3": 0.25955, "Y3": 0.5718, "X4": 0.16996, "Y4": 0.5738, "page": 0}, {"Word": "Embassy", "Confidence": 0.162, "X1": 0.50461, "Y1": 0.5632, "X2": 0.55072, "Y2": 0.563, "X3": 0.55072, "Y3": 0.5728, "X4": 0.50461, "Y4": 0.5718, "page": 0}, {"Word": "Other King Summ", "Confidence": 0.546, "X1": 0.68248, "Y1": 0.5642, "X2": 0.76416, "Y2": 0.564, "X3": 0.76416, "Y3": 0.5728, "X4": 0.68248, "Y4": 0.5728, "page": 0}, {"Word": "6 Schenker MB. Samet JM. Sprimer FE. Effect of cigarette", "Confidence": 0.6462, "X1": 0.15283, "Y1": 0.5722, "X2": 0.48748, "Y2": 0.572, "X3": 0.48748, "Y3": 0.5838, "X4": 0.15283, "Y4": 0.5848, "page": 0}, {"Word": "Gold Leaf", "Confidence": 0.4455, "X1": 0.50593, "Y1": 0.5722, "X2": 0.55863, "Y2": 0.572, "X3": 0.55863, "Y3": 0.5838, "X4": 0.50593, "Y4": 0.5838, "page": 0}, {"Word": "tar content and smoking habits on mapiratory symptoms", "Confidence": 0.526, "X1": 0.16733, "Y1": 0.5832, "X2": 0.4888, "Y2": 0.583, "X3": 0.4888, "Y3": 0.5958, "X4": 0.16733, "Y4": 0.5948, "page": 0}, {"Word": "Guarda", "Confidence": 0.612, "X1": 0.50461, "Y1": 0.5842, "X2": 0.54414, "Y2": 0.584, "X3": 0.54414, "Y3": 0.5928, "X4": 0.50461, "Y4": 0.5928, "page": 0}, {"Word": "in women. Am Rev Respir Die 1982:125:684-90.", "Confidence": 0.48886, "X1": 0.16601, "Y1": 0.5932, "X2": 0.44664, "Y2": 0.593, "X3": 0.44664, "Y3": 0.6048, "X4": 0.16601, "Y4": 0.6058, "page": 0}, {"Word": "Que ordinary", "Confidence": 0.127, "X1": 0.68248, "Y1": 0.5952, "X2": 0.75626, "Y2": 0.595, "X3": 0.75626, "Y3": 0.6028, "X4": 0.68248, "Y4": 0.6028, "page": 0}, {"Word": "Comstock GW, Brownlow WI. Stane RW. Surtved PE.", "Confidence": 0.48463, "X1": 0.16469, "Y1": 0.6042, "X2": 0.48485, "Y2": 0.604, "X3": 0.48485, "Y3": 0.6158, "X4": 0.16469, "Y4": 0.6168, "page": 0}, {"Word": "Mayfair", "Confidence": 0.641, "X1": 0.50066, "Y1": 0.6042, "X2": 0.55072, "Y2": 0.604, "X3": 0.54941, "Y3": 0.6138, "X4": 0.50066, "Y4": 0.6118, "page": 0}, {"Word": "Tabacre (not specified!)", "Confidence": 0.30433, "X1": 0.68379, "Y1": 0.6042, "X2": 0.79974, "Y2": 0.604, "X3": 0.79974, "Y3": 0.6138, "X4": 0.68379, "Y4": 0.6128, "page": 0}, {"Word": "Oprette smoking sed changes in respiratory Andingt.", "Confidence": 0.425, "X1": 0.1726, "Y1": 0.6162, "X2": 0.48617, "Y2": 0.616, "X3": 0.48617, "Y3": 0.6278, "X4": 0.1726, "Y4": 0.6268, "page": 0}, {"Word": "Beers Head", "Confidence": 0.6065, "X1": 0.67984, "Y1": 0.6142, "X2": 0.7444, "Y2": 0.614, "X3": 0.7444, "Y3": 0.6218, "X4": 0.67984, "Y4": 0.6218, "page": 0}, {"Word": "Arch Environ Health 1970-21:50-1.", "Confidence": 0.63025, "X1": 0.16996, "Y1": 0.6252, "X2": 0.36891, "Y2": 0.625, "X3": 0.36891, "Y3": 0.6368, "X4": 0.16996, "Y4": 0.6378, "page": 0}, {"Word": "Golden Virginia", "Confidence": 0.2055, "X1": 0.67984, "Y1": 0.6242, "X2": 0.76285, "Y2": 0.624, "X3": 0.76285, "Y3": 0.6338, "X4": 0.67984, "Y4": 0.6338, "page": 0}, {"Word": "Hammond EC, Garfinkel L. 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Smokers who returned a packet", "Confidence": 0.783, "X1": 0.52833, "Y1": 0.2812, "X2": 0.87484, "Y2": 0.281, "X3": 0.87352, "Y3": 0.2938, "X4": 0.52833, "Y4": 0.2928, "page": 0}, {"Word": "of 1204, stratified according to whether they were", "Confidence": 0.72888, "X1": 0.17391, "Y1": 0.2922, "X2": 0.51383, "Y2": 0.292, "X3": 0.51383, "Y3": 0.3058, "X4": 0.17391, "Y4": 0.3048, "page": 0}, {"Word": "carrying a brand name or tar group that did not agree", "Confidence": 0.74609, "X1": 0.52964, "Y1": 0.2942, "X2": 0.87352, "Y2": 0.294, "X3": 0.87352, "Y3": 0.3078, "X4": 0.52964, "Y4": 0.3068, "page": 0}, {"Word": "retired, were sent a self administered questionnaire in", "Confidence": 0.68425, "X1": 0.1726, "Y1": 0.3052, "X2": 0.51647, "Y2": 0.305, "X3": 0.51647, "Y3": 0.3178, "X4": 0.1726, "Y4": 0.3178, "page": 0}, {"Word": "with those given on the questionnaire were asked by", "Confidence": 0.90167, "X1": 0.52964, "Y1": 0.3062, "X2": 0.8722, "Y2": 0.306, "X3": 0.8722, "Y3": 0.3198, "X4": 0.52964, "Y4": 0.3198, "page": 0}, {"Word": ".1984. This inquired about the type (plain, Alter, or", "Confidence": 0.65422, "X1": 0.1726, "Y1": 0.3182, "X2": 0.51779, "Y2": 0.318, "X3": 0.51647, "Y3": 0.3318, "X4": 0.1726, "Y4": 0.3298, "page": 0}, {"Word": "letter or telephone whether they had changed brands", "Confidence": 0.82525, "X1": 0.52964, "Y1": 0.3192, "X2": 0.8722, "Y2": 0.319, "X3": 0.8722, "Y3": 0.3318, "X4": 0.52964, "Y4": 0.3328, "page": 0}, {"Word": "buind rolled), tar group (\"bigh.\" \"middle high.\"", "Confidence": 0.532, "X1": 0.17523, "Y1": 0.3272, "X2": 0.51647, "Y2": 0.327, "X3": 0.51647, "Y3": 0.3438, "X4": 0.17655, "Y4": 0.3448, "page": 0}, {"Word": "tinos completing the questionnaire. The question-", "Confidence": 0.85483, "X1": 0.52964, "Y1": 0.3312, "X2": 0.87088, "Y2": 0.331, "X3": 0.8722, "Y3": 0.3448, "X4": 0.52964, "Y4": 0.3448, "page": 0}, {"Word": "\"middle,\" \"low middle,\" \"low.\" \"not known\"],", "Confidence": 0.86633, "X1": 0.1726, "Y1": 0.3422, "X2": 0.5191, "Y2": 0.342, "X3": 0.51779, "Y3": 0.3568, "X4": 0.1726, "Y4": 0.3548, "page": 0}, {"Word": "aaire inquired about the length of time that the men", "Confidence": 0.7742, "X1": 0.52701, "Y1": 0.3442, "X2": 0.87088, "Y2": 0.344, "X3": 0.87088, "Y3": 0.3578, "X4": 0.52701, "Y4": 0.3568, "page": 0}, {"Word": "brand name, and the number of years they had", "Confidence": 0.881, "X1": 0.17523, "Y1": 0.3552, "X2": 0.5191, "Y2": 0.355, "X3": 0.5191, "Y3": 0.3688, "X4": 0.17523, "Y4": 0.3688, "page": 0}, {"Word": "had been smoking their cigarette brands and we could", "Confidence": 0.85144, "X1": 0.52833, "Y1": 0.3562, "X2": 0.87352, "Y2": 0.356, "X3": 0.8722, "Y3": 0.3708, "X4": 0.52833, "Y4": 0.3698, "page": 0}, {"Word": "smoked their usual present cigarettes and the brand", "Confidence": 0.71275, "X1": 0.1726, "Y1": 0.3672, "X2": 0.51647, "Y2": 0.367, "X3": 0.51647, "Y3": 0.3808, "X4": 0.1726, "Y4": 0.3808, "page": 0}, {"Word": "therefore check whether the brands cited were likely", "Confidence": 0.84175, "X1": 0.52306, "Y1": 0.3692, "X2": 0.8722, "Y2": 0.369, "X3": 0.8722, "Y3": 0.3828, "X4": 0.52306, "Y4": 0.3818, "page": 0}, {"Word": "of cigarettes they thought they had been smoking at", "Confidence": 0.84856, "X1": 0.17391, "Y1": 0.3792, "X2": 0.51515, "Y2": 0.379, "X3": 0.51515, "Y3": 0.3938, "X4": 0.17391, "Y4": 0.3938, "page": 0}, {"Word": "to be the smoker's usual brands. The brand alleged to", "Confidence": 0.8662, "X1": 0.52437, "Y1": 0.3822, "X2": 0.8722, "Y2": 0.382, "X3": 0.8722, "Y3": 0.3958, "X4": 0.52437, "Y4": 0.3948, "page": 0}, {"Word": "the start of the project.", "Confidence": 0.8676, "X1": 0.17655, "Y1": 0.3942, "X2": 0.32806, "Y2": 0.394, "X3": 0.32806, "Y3": 0.4068, "X4": 0.17655, "Y4": 0.4058, "page": 0}, {"Word": "have been smoked 12 years ago was also compared", "Confidence": 0.80533, "X1": 0.52964, "Y1": 0.3952, "X2": 0.8722, "Y2": 0.395, "X3": 0.8722, "Y3": 0.4088, "X4": 0.52964, "Y4": 0.4078, "page": 0}, {"Word": "The respondents were asked to give the brand", "Confidence": 0.88775, "X1": 0.19499, "Y1": 0.4042, "X2": 0.51252, "Y2": 0.404, "X3": 0.51252, "Y3": 0.4198, "X4": 0.19499, "Y4": 0.4198, "page": 0}, {"Word": "with that actually recorded at the start of the project.", "Confidence": 0.9153, "X1": 0.53096, "Y1": 0.4082, "X2": 0.87352, "Y2": 0.408, "X3": 0.87352, "Y3": 0.4218, "X4": 0.53096, "Y4": 0.4208, "page": 0}, {"Word": "names as fully as possible and to include any words", "Confidence": 0.8571, "X1": 0.17787, "Y1": 0.4182, "X2": 0.51252, "Y2": 0.418, "X3": 0.51252, "Y3": 0.4318, "X4": 0.17787, "Y4": 0.4328, "page": 0}, {"Word": "such as \"King Size,\" letters as in \"Craven A.\" or", "Confidence": 0.8912, "X1": 0.17655, "Y1": 0.4312, "X2": 0.51515, "Y2": 0.431, "X3": 0.51515, "Y3": 0.4438, "X4": 0.17655, "Y4": 0.4448, "page": 0}, {"Word": "numbers as in \"State Express $55\" written on the", "Confidence": 0.59856, "X1": 0.17787, "Y1": 0.4432, "X2": 0.51515, "Y2": 0.443, "X3": 0.51515, "Y3": 0.4568, "X4": 0.17787, "Y4": 0.4568, "page": 0}, {"Word": "Resaits", "Confidence": 0.703, "X1": 0.52964, "Y1": 0.4382, "X2": 0.58235, "Y2": 0.438, "X3": 0.58235, "Y3": 0.4508, "X4": 0.52833, "Y4": 0.4488, "page": 0}, {"Word": "front, beck, or sides of the cigarette packet. The", "Confidence": 0.84756, "X1": 0.17523, "Y1": 0.4562, "X2": 0.51779, "Y2": 0.456, "X3": 0.51779, "Y3": 0.4698, "X4": 0.17523, "Y4": 0.4698, "page": 0}, {"Word": "The response rate to the questionnaire after three", "Confidence": 0.7715, "X1": 0.5336, "Y1": 0.4612, "X2": 0.87747, "Y2": 0.461, "X3": 0.87747, "Y3": 0.4758, "X4": 0.5336, "Y4": 0.4758, "page": 0}, {"Word": "present cigarette brands were coded by one observer", "Confidence": 0.79587, "X1": 0.1726, "Y1": 0.4692, "X2": 0.51647, "Y2": 0.469, "X3": 0.51647, "Y3": 0.4818, "X4": 0.1726, "Y4": 0.4828, "page": 0}, {"Word": "using a dictionary of brands on the market since 1978", "Confidence": 0.8167, "X1": 0.17391, "Y1": 0.4822, "X2": 0.51383, "Y2": 0.482, "X3": 0.51383, "Y3": 0.4948, "X4": 0.17391, "Y4": 0.4948, "page": 0}, {"Word": "mailing was 83%. Intervention and control factory", "Confidence": 0.77114, "X1": 0.52701, "Y1": 0.4752, "X2": 0.87615, "Y2": 0.475, "X3": 0.87484, "Y3": 0.4888, "X4": 0.52701, "Y4": 0.4888, "page": 0}, {"Word": "(PN Les, personal communication), to which hand", "Confidence": 0.80043, "X1": 0.17391, "Y1": 0.4942, "X2": 0.51515, "Y2": 0.494, "X3": 0.51515, "Y3": 0.5078, "X4": 0.17391, "Y4": 0.5078, "page": 0}, {"Word": "workers were similar with respect to response, social", "Confidence": 0.86575, "X1": 0.53096, "Y1": 0.4882, "X2": 0.87615, "Y2": 0.488, "X3": 0.87615, "Y3": 0.5008, "X4": 0.53096, "Y4": 0.5008, "page": 0}, {"Word": "class, and smoking habits 12 years previously. The", "Confidence": 0.82025, "X1": 0.53491, "Y1": 0.5002, "X2": 0.87747, "Y2": 0.5, "X3": 0.87747, "Y3": 0.5138, "X4": 0.5336, "Y4": 0.5128, "page": 0}, {"Word": "rolled tobaccos were added. If the brand information", "Confidence": 0.77713, "X1": 0.17655, "Y1": 0.5082, "X2": 0.51252, "Y2": 0.508, "X3": 0.51252, "Y3": 0.5198, "X4": 0.17655, "Y4": 0.5188, "page": 0}, {"Word": "respondents from the five intervention factories, how-", "Confidence": 0.74871, "X1": 0.5336, "Y1": 0.5122, "X2": 0.87615, "Y2": 0.512, "X3": 0.87615, "Y3": 0.5258, "X4": 0.5336, "Y4": 0.5248, "page": 0}, {"Word": "in the questionnaire could not be matched with only", "Confidence": 0.86667, "X1": 0.17787, "Y1": 0.5202, "X2": 0.51383, "Y2": 0.52, "X3": 0.51383, "Y3": 0.5328, "X4": 0.17787, "Y4": 0.5328, "page": 0}, {"Word": "ever, were slightly older (60.7 compared with 59.7", "Confidence": 0.712, "X1": 0.5336, "Y1": 0.5242, "X2": 0.87747, "Y2": 0.524, "X3": 0.87747, "Y3": 0.5368, "X4": 0.5336, "Y4": 0.5388, "page": 0}, {"Word": "one dgarette described in the dictionary then the", "Confidence": 0.829, "X1": 0.17523, "Y1": 0.5322, "X2": 0.51515, "Y2": 0.532, "X3": 0.51515, "Y3": 0.5448, "X4": 0.17523, "Y4": 0.5448, "page": 0}, {"Word": "questionnaire data were recorded as uncodable. For", "Confidence": 0.88186, "X1": 0.17787, "Y1": 0.5452, "X2": 0.51647, "Y2": 0.545, "X3": 0.51647, "Y3": 0.5578, "X4": 0.17787, "Y4": 0.5588, "page": 0}, {"Word": "years: p < 0.05). Non-respondents were similar to", "Confidence": 0.73375, "X1": 0.5336, "Y1": 0.5372, "X2": 0.87615, "Y2": 0.537, "X3": 0.87615, "Y3": 0.5508, "X4": 0.5336, "Y4": 0.5518, "page": 0}, {"Word": "respondents in age, social class, and smoking habits", "Confidence": 0.87788, "X1": 0.53096, "Y1": 0.5502, "X2": 0.87484, "Y2": 0.55, "X3": 0.87484, "Y3": 0.5638, "X4": 0.53096, "Y4": 0.5638, "page": 0}, {"Word": "example,", "Confidence": 0.66, "X1": 0.17787, "Y1": 0.5592, "X2": 0.23979, "Y2": 0.559, "X3": 0.23979, "Y3": 0.5698, "X4": 0.17787, "Y4": 0.5688, "page": 0}, {"Word": "12 years before. Workers from the 10 factories", "Confidence": 0.8455, "X1": 0.53623, "Y1": 0.5622, "X2": 0.87615, "Y2": 0.562, "X3": 0.87615, "Y3": 0.5758, "X4": 0.53623, "Y4": 0.5758, "page": 0}, {"Word": "Questionnaire brand:", "Confidence": 0.7535, "X1": 0.19499, "Y1": 0.5692, "X2": 0.32806, "Y2": 0.569, "X3": 0.32806, "Y3": 0.5838, "X4": 0.19499, "Y4": 0.5838, "page": 0}, {"Word": "surveyed in this study were also compared with the", "Confidence": 0.89722, "X1": 0.53491, "Y1": 0.5742, "X2": 0.87879, "Y2": 0.574, "X3": 0.87879, "Y3": 0.5878, "X4": 0.53491, "Y4": 0.5888, "page": 0}, {"Word": "Player's No 6", "Confidence": 0.888, "X1": 0.2108, "Y1": 0.5822, "X2": 0.3004, "Y2": 0.582, "X3": 0.3004, "Y3": 0.5938, "X4": 0.2108, "Y4": 0.5938, "page": 0}, {"Word": "Dictionary brands:", "Confidence": 0.694, "X1": 0.19895, "Y1": 0.5962, "X2": 0.31357, "Y2": 0.596, "X3": 0.31357, "Y3": 0.6078, "X4": 0.19763, "Y4": 0.6068, "page": 0}, {"Word": "original 24 factory populations with respect to their", "Confidence": 0.89862, "X1": 0.5336, "Y1": 0.5872, "X2": 0.88011, "Y2": 0.587, "X3": 0.88011, "Y3": 0.6008, "X4": 0.5336, "Y4": 0.6008, "page": 0}, {"Word": "characteristics on entry. Smoking was slightly less", "Confidence": 0.76343, "X1": 0.53491, "Y1": 0.6002, "X2": 0.88011, "Y2": 0.6, "X3": 0.88011, "Y3": 0.6148, "X4": 0.53491, "Y4": 0.6148, "page": 0}, {"Word": "309 Player's No 6 Filter", "Confidence": 0.9792, "X1": 0.20685, "Y1": 0.6082, "X2": 0.36495, "Y2": 0.608, "X3": 0.36495, "Y3": 0.6208, "X4": 0.20553, "Y4": 0.6188, "page": 0}, {"Word": "SF 1965-", "Confidence": 0.8165, "X1": 0.45059, "Y1": 0.6052, "X2": 0.5191, "Y2": 0.605, "X3": 0.5191, "Y3": 0.6188, "X4": 0.45059, "Y4": 0.6198, "page": 0}, {"Word": "common in the 10 chosea factories than in the", "Confidence": 0.84567, "X1": 0.53491, "Y1": 0.6112, "X2": 0.87879, "Y2": 0.611, "X3": 0.87879, "Y3": 0.6258, "X4": 0.53491, "Y4": 0.6268, "page": 0}, {"Word": "101 Player's No 6 Plain", "Confidence": 0.8558, "X1": 0.2108, "Y1": 0.6212, "X2": 0.36627, "Y2": 0.621, "X3": 0.36627, "Y3": 0.6328, "X4": 0.2108, "Y4": 0.6328, "page": 0}, {"Word": "SP 1965-", "Confidence": 0.8865, "X1": 0.45059, "Y1": 0.6202, "X2": 0.52042, "Y2": 0.62, "X3": 0.52042, "Y3": 0.6318, "X4": 0.45059, "Y4": 0.6328, "page": 0}, {"Word": "310 Player's No 6 Extra Mild Filter SF 1972-", "Confidence": 0.86889, "X1": 0.21212, "Y1": 0.6332, "X2": 0.52174, "Y2": 0.633, "X3": 0.52174, "Y3": 0.6458, "X4": 0.21212, "Y4": 0.6458, "page": 0}, {"Word": "remaining 14. The ages of the two populations were", "Confidence": 0.92422, "X1": 0.53491, "Y1": 0.6252, "X2": 0.87879, "Y2": 0.625, "X3": 0.87879, "Y3": 0.6388, "X4": 0.53491, "Y4": 0.6388, "page": 0}, {"Word": "similar.", "Confidence": 0.635, "X1": 0.53623, "Y1": 0.6392, "X2": 0.5863, "Y2": 0.639, "X3": 0.58498, "Y3": 0.6508, "X4": 0.53623, "Y4": 0.6498, "page": 0}, {"Word": "618 Player's No 6 King Size Filter KS F 1971-", "Confidence": 0.907, "X1": 0.2108, "Y1": 0.6462, "X2": 0.52042, "Y2": 0.646, "X3": 0.52042, "Y3": 0.6588, "X4": 0.2108, "Y4": 0.6588, "page": 0}, {"Word": "Four hundred and twenty nine men who returned &", "Confidence": 0.85589, "X1": 0.54282, "Y1": 0.6512, "X2": 0.87747, "Y2": 0.651, "X3": 0.87747, "Y3": 0.6648, "X4": 0.54282, "Y4": 0.6638, "page": 0}, {"Word": "(Ssmall; KS-King Size; F-alter; P-plain)", "Confidence": 0.691, "X1": 0.19368, "Y1": 0.6592, "X2": 0.50066, "Y2": 0.659, "X3": 0.50066, "Y3": 0.6738, "X4": 0.19368, "Y4": 0.6738, "page": 0}, {"Word": "questionnaire 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It is concluded that current smokers should be asked to return an", "Confidence": 0.87161, "X1": 0.14493, "Y1": 0.4662, "X2": 0.83531, "Y2": 0.466, "X3": 0.83531, "Y3": 0.4808, "X4": 0.14493, "Y4": 0.4798, "page": 0}, {"Word": "empty packet or packets of the cigarette brand of brands usually smoked with a self administered", "Confidence": 0.91594, "X1": 0.14361, "Y1": 0.4802, "X2": 0.83399, "Y2": 0.48, "X3": 0.83399, "Y3": 0.4938, "X4": 0.14361, "Y4": 0.4948, "page": 0}, {"Word": "questionnaire and that follow up studies of populations for which brands of cigarette smoked were", "Confidence": 0.95053, "X1": 0.14361, "Y1": 0.4932, "X2": 0.83663, "Y2": 0.493, "X3": 0.83663, "Y3": 0.5078, "X4": 0.14361, "Y4": 0.5078, "page": 0}, {"Word": "previously recorded might be more valid.than studies relying on recall.", "Confidence": 0.9353, "X1": 0.14361, "Y1": 0.5072, "X2": 0.6469, "Y2": 0.507, "X3": 0.6469, "Y3": 0.5218, "X4": 0.14361, "Y4": 0.5218, "page": 0}, {"Word": "Several studies have attempted to establish whether", "Confidence": 0.76086, "X1": 0.14493, "Y1": 0.5382, "X2": 0.4888, "Y2": 0.538, "X3": 0.48748, "Y3": 0.5528, "X4": 0.14493, "Y4": 0.5518, "page": 0}, {"Word": "ing brands on bealth may have to collect information", "Confidence": 0.88344, "X1": 0.49407, "Y1": 0.5382, "X2": 0.83926, "Y2": 0.538, "X3": 0.83794, "Y3": 0.5528, "X4": 0.49407, "Y4": 0.5518, "page": 0}, {"Word": "there is any benefit to cigarette smokers in changing", "Confidence": 0.89867, "X1": 0.14493, "Y1": 0.5512, "X2": 0.48221, "Y2": 0.551, "X3": 0.48221, "Y3": 0.5638, "X4": 0.14493, "Y4": 0.5638, "page": 0}, {"Word": "on brands on the basis of recall over & long period", "Confidence": 0.73945, "X1": 0.49802, "Y1": 0.5512, "X2": 0.83794, "Y2": 0.551, "X3": 0.83794, "Y3": 0.5648, "X4": 0.49802, "Y4": 0.5638, "page": 0}, {"Word": "from a higher to a lower ur brand. Most of these are", "Confidence": 0.76267, "X1": 0.14625, "Y1": 0.5632, "X2": 0.48353, "Y2": 0.563, "X3": 0.48353, "Y3": 0.5768, "X4": 0.14625, "Y4": 0.5768, "page": 0}, {"Word": "because of the time taken for some effects to become", "Confidence": 0.8064, "X1": 0.49275, "Y1": 0.5642, "X2": 0.83663, "Y2": 0.564, "X3": 0.83663, "Y3": 0.5778, "X4": 0.49275, "Y4": 0.5758, "page": 0}, {"Word": "cross sectional,' \"* prospective,'\"13 of retro-", "Confidence": 0.634, "X1": 0.14625, "Y1": 0.5752, "X2": 0.48748, "Y2": 0.575, "X3": 0.48748, "Y3": 0.5908, "X4": 0.14625, "Y4": 0.5908, "page": 0}, {"Word": "apparent. For example, Fletcher et af' showed that", "Confidence": 0.64412, "X1": 0.49802, "Y1": 0.5762, "X2": 0.83794, "Y2": 0.576, "X3": 0.83794, "Y3": 0.5898, "X4": 0.49802, "Y4": 0.5908, "page": 0}, {"Word": "spective'-16 studies in which information about", "Confidence": 0.8415, "X1": 0.14493, "Y1": 0.5892, "X2": 0.48353, "Y2": 0.589, "X3": 0.48353, "Y3": 0.6038, "X4": 0.14493, "Y4": 0.6008, "page": 0}, {"Word": "at least eight years of follow up is anoded to dis-", "Confidence": 0.83427, "X1": 0.49802, "Y1": 0.5892, "X2": 0.83794, "Y2": 0.589, "X3": 0.83794, "Y3": 0.6028, "X4": 0.49802, "Y4": 0.6028, "page": 0}, {"Word": "cigarette type and brand, present or past or both, had", "Confidence": 0.8301, "X1": 0.14625, "Y1": 0.6012, "X2": 0.48353, "Y2": 0.601, "X3": 0.48353, "Y3": 0.6148, "X4": 0.14625, "Y4": 0.6148, "page": 0}, {"Word": "tinguish even between smokers and ex-smokers on the", "Confidence": 0.70663, "X1": 0.49934, "Y1": 0.6022, "X2": 0.83794, "Y2": 0.602, "X3": 0.83794, "Y3": 0.6148, "X4": 0.49934, "Y4": 0.6148, "page": 0}, {"Word": "to be obtained from smokers themselves. None of", "Confidence": 0.88175, "X1": 0.14888, "Y1": 0.6142, "X2": 0.48485, "Y2": 0.614, "X3": 0.48485, "Y3": 0.6278, "X4": 0.14888, "Y4": 0.6268, "page": 0}, {"Word": "basis of lung function tests. Moreover, the validity of", "Confidence": 0.79511, "X1": 0.49934, "Y1": 0.6142, "X2": 0.83926, "Y2": 0.614, "X3": 0.83926, "Y3": 0.6278, "X4": 0.49934, "Y4": 0.6268, "page": 0}, {"Word": "these studies tested the validity of smokers' taswers", "Confidence": 0.843, "X1": 0.14756, "Y1": 0.6272, "X2": 0.48617, "Y2": 0.627, "X3": 0.48617, "Y3": 0.6408, "X4": 0.14756, "Y4": 0.6398, "page": 0}, {"Word": "information about current cigarettes smoked (type.", "Confidence": 0.61417, "X1": 0.49802, "Y1": 0.6272, "X2": 0.83926, "Y2": 0.627, "X3": 0.83926, "Y3": 0.6418, "X4": 0.49802, "Y4": 0.6408, "page": 0}, {"Word": "about past and present cigarette type and brand. This", "Confidence": 0.84533, "X1": 0.14625, "Y1": 0.6392, "X2": 0.48617, "Y2": 0.639, "X3": 0.48617, "Y3": 0.6528, "X4": 0.14625, "Y4": 0.6528, "page": 0}, {"Word": "tar group, or brand name) has never been established.", "Confidence": 0.85233, "X1": 0.49407, "Y1": 0.6392, "X2": 0.83794, "Y2": 0.639, "X3": 0.83794, "Y3": 0.6528, "X4": 0.49407, "Y4": 0.6528, "page": 0}, {"Word": "is surprising, not only because of the fundamental", "Confidence": 0.89925, "X1": 0.14493, "Y1": 0.6522, "X2": 0.48353, "Y2": 0.652, "X3": 0.48353, "Y3": 0.6658, "X4": 0.14493, "Y4": 0.6648, "page": 0}, {"Word": "for example, against the details on the packet,", "Confidence": 0.834, "X1": 0.50066, "Y1": 0.6522, "X2": 0.79974, "Y2": 0.652, "X3": 0.79974, "Y3": 0.6648, "X4": 0.50066, "Y4": 0.6638, "page": 0}, {"Word": "nature of the information but also because the", "Confidence": 0.85263, "X1": 0.14888, "Y1": 0.6642, "X2": 0.48353, "Y2": 0.664, "X3": 0.48353, "Y3": 0.6778, "X4": 0.14888, "Y4": 0.6768, "page": 0}, {"Word": "In this paper we assess the validity of smokers'", "Confidence": 0.932, "X1": 0.5112, "Y1": 0.6642, "X2": 0.83926, "Y2": 0.664, "X3": 0.83926, "Y3": 0.6778, "X4": 0.5112, "Y4": 0.6768, "page": 0}, {"Word": "Tobacco Research Council showed 20 years ago that", "Confidence": 0.6945, "X1": 0.14493, "Y1": 0.6782, "X2": 0.48617, "Y2": 0.678, "X3": 0.48617, "Y3": 0.6908, "X4": 0.14493, "Y4": 0.6888, "page": 0}, {"Word": "information about present and past cigarette brands", "Confidence": 0.87186, "X1": 0.49539, "Y1": 0.6772, "X2": 0.83926, "Y2": 0.677, "X3": 0.83926, "Y3": 0.6898, "X4": 0.49539, "Y4": 0.6888, "page": 0}, {"Word": "the proportion of smokers of manufactured and hand", "Confidence": 0.867, "X1": 0.14888, "Y1": 0.6902, "X2": 0.48485, "Y2": 0.69, "X3": 0.48485, "Y3": 0.7038, "X4": 0.14888, "Y4": 0.7018, "page": 0}, {"Word": "and discuss the implications of the results for past and", "Confidence": 0.8349, "X1": 0.49539, "Y1": 0.6902, "X2": 0.83926, "Y2": 0.69, "X3": 0.83794, "Y3": 0.7038, "X4": 0.49407, "Y4": 0.7008, "page": 0}, {"Word": "rolled cigarettes incorrectly recalling even the type of", "Confidence": 0.739, "X1": 0.14888, "Y1": 0.7022, "X2": 0.48617, "Y2": 0.702, "X3": 0.48617, "Y3": 0.7168, "X4": 0.14888, "Y4": 0.7148, "page": 0}, {"Word": "future studies of the effects of the falling tar yields of", "Confidence": 0.91655, "X1": 0.49539, "Y1": 0.7022, "X2": 0.8419, "Y2": 0.702, "X3": 0.8419, "Y3": 0.7158, "X4": 0.49539, "Y4": 0.7138, "page": 0}, {"Word": "cigarettes on health.", "Confidence": 0.72633, "X1": 0.49671, "Y1": 0.7142, "X2": 0.63109, "Y2": 0.714, "X3": 0.63109, "Y3": 0.7268, "X4": 0.49671, "Y4": 0.7278, "page": 0}, {"Word": "cigarette (manufactured or hand rolled) they had", "Confidence": 0.728, "X1": 0.1502, "Y1": 0.7152, "X2": 0.49275, "Y2": 0.715, "X3": 0.49275, "Y3": 0.7288, "X4": 0.1502, "Y4": 0.7278, "page": 0}, {"Word": "smoked increased from an average of 8% one and &", "Confidence": 0.6521, "X1": 0.14756, "Y1": 0.7272, "X2": 0.48353, "Y2": 0.727, "X3": 0.48353, "Y3": 0.7408, "X4": 0.14756, "Y4": 0.7398, "page": 0}, {"Word": "half years after the initial interview to 35% at 15", "Confidence": 0.7677, "X1": 0.14888, "Y1": 0.7372, "X2": 0.49275, "Y2": 0.737, "X3": 0.49275, "Y3": 0.7518, "X4": 0.14888, "Y4": 0.7528, "page": 0}, {"Word": "Method", "Confidence": 0.325, "X1": 0.49539, "Y1": 0.7382, "X2": 0.55468, "Y2": 0.738, "X3": 0.55468, "Y3": 0.7518, "X4": 0.49539, "Y4": 0.7508, "page": 0}, {"Word": "years \"\" Recall of the actual brand name of cigarettes", "Confidence": 0.6665, "X1": 0.14756, "Y1": 0.7532, "X2": 0.48485, "Y2": 0.753, "X3": 0.48485, "Y3": 0.7658, "X4": 0.14756, "Y4": 0.7638, "page": 0}, {"Word": "smoked in the past is likely to be even poorer. Retro-", "Confidence": 0.87155, "X1": 0.14625, "Y1": 0.7652, "X2": 0.48485, "Y2": 0.765, "X3": 0.48485, "Y3": 0.7768, "X4": 0.14625, "Y4": 0.7768, "page": 0}, {"Word": "The Heart Disease Prevention Project was & random-", "Confidence": 0.65163, "X1": 0.49934, "Y1": 0.7642, "X2": 0.8419, "Y2": 0.764, "X3": 0.8419, "Y3": 0.7788, "X4": 0.49934, "Y4": 0.7758, "page": 0}, {"Word": "spective studies trying to assess the effects of switch-", "Confidence": 0.76678, "X1": 0.14888, "Y1": 0.7772, "X2": 0.48485, "Y2": 0.777, "X3": 0.48485, "Y3": 0.7898, "X4": 0.14888, "Y4": 0.7898, "page": 0}, {"Word": "ised controlled trial of the benefits to middle aged", "Confidence": 0.87944, "X1": 0.49539, "Y1": 0.7762, "X2": 0.8419, "Y2": 0.776, "X3": 0.8419, "Y3": 0.7898, "X4": 0.49539, "Y4": 0.7888, "page": 0}, {"Word": "men of mounting a preventive campaign in indus-", "Confidence": 0.88762, "X1": 0.50066, "Y1": 0.7892, "X2": 0.83926, "Y2": 0.789, "X3": 0.83926, "Y3": 0.8018, "X4": 0.50066, "Y4": 0.8028, "page": 0}, {"Word": "try.\" At the start of the study in 1971-3 a self admin- .", "Confidence": 0.84515, "X1": 0.50198, "Y1": 0.8012, "X2": 0.84585, "Y2": 0.801, "X3": 0.84585, "Y3": 0.8148, "X4": 0.50198, "Y4": 0.8148, "page": 0}, {"Word": "Addres Cor onargendeno: Mr RW Morris. Drperonnn of Con-", "Confidence": 0.49778, "X1": 0.14888, "Y1": 0.8132, "X2": 0.48485, "Y2": 0.813, "X3": 0.48485, "Y3": 0.8258, "X4": 0.14888, "Y4": 0.8258, "page": 0}, {"Word": "istered questionnaire was used to obtain data on the", "Confidence": 0.90178, "X1": 0.50066, "Y1": 0.8152, "X2": 0.83926, "Y2": 0.815, "X3": 0.83926, "Y3": 0.8278, "X4": 0.50066, "Y4": 0.8268, "page": 0}, {"Word": "Dominy Medona, St Thomas's Hospital Medical School, Lasdos", "Confidence": 0.35825, "X1": 0.14756, "Y1": 0.8232, "X2": 0.48617, "Y2": 0.823, "X3": 0.48617, "Y3": 0.8368, "X4": 0.14756, "Y4": 0.8358, "page": 0}, {"Word": "321 TEM.", "Confidence": 0.277, "X1": 0.1502, "Y1": 0.8322, "X2": 0.20553, "Y2": 0.832, "X3": 0.20422, "Y3": 0.8448, "X4": 0.14888, "Y4": 0.8438, "page": 0}, {"Word": "type and brand of cigarette smoked from all men", "Confidence": 0.79067, "X1": 0.50066, "Y1": 0.8272, "X2": 0.83926, "Y2": 0.827, "X3": 0.83926, "Y3": 0.8408, "X4": 0.50066, "Y4": 0.8398, "page": 0}, {"Word": "employed in the 12 intervention factories and 10% of", "Confidence": 0.88922, "X1": 0.50198, "Y1": 0.8402, "X2": 0.83794, "Y2": 0.84, "X3": 0.83794, "Y3": 0.8528, "X4": 0.50198, "Y4": 0.8528, "page": 0}, {"Word": "those in the 12 control factories. The men were asked", "Confidence": 0.8408, "X1": 0.50329, "Y1": 0.8522, "X2": 0.83926, "Y2": 0.852, "X3": 0.83926, "Y3": 0.8658, "X4": 0.50329, "Y4": 0.8658, "page": 0}, {"Word": "201", "Confidence": 0.781, "X1": 0.48748, "Y1": 0.8712, "X2": 0.50988, "Y2": 0.871, "X3": 0.50856, "Y3": 0.8808, "X4": 0.48617, "Y4": 0.8808, "page": 0}, {"Word": ".-.....", "Confidence": 0.326, "X1": 0.42292, "Y1": 0.9592, "X2": 0.4809, "Y2": 0.959, "X3": 0.4809, "Y3": 0.9658, "X4": 0.42292, "Y4": 0.9658, "page": 0}, {"Word": "104758935", "Confidence": 0.991, "X1": 0.89987, "Y1": 0.9902, "X2": 0.90909, "Y2": 0.99, "X3": 0.87352, "Y3": 0.9908, "X4": 0.86693, "Y4": 0.8728, "page": 0}], "words_data": [{"Word": "6", "Confidence": 0.068, "X1": 0.70751, "Y1": 0.0322, "X2": 0.72991, "Y2": 0.032, "X3": 0.72991, "Y3": 0.0558, "X4": 0.70883, "Y4": 0.0568, "page": 0, "Index": 0}, {"Word": ".", "Confidence": 0.498, "X1": 0.74704, "Y1": 0.0322, "X2": 0.76416, "Y2": 0.032, "X3": 0.76548, "Y3": 0.0558, "X4": 0.74835, "Y4": 0.0558, "page": 0, "Index": 1}, {"Word": "Ta", "Confidence": 0.492, "X1": 0.64163, "Y1": 0.1172, "X2": 0.66271, "Y2": 0.117, "X3": 0.66271, "Y3": 0.1328, "X4": 0.64295, "Y4": 0.1328, "page": 0, "Index": 2}, {"Word": "701", "Confidence": 0.998, "X1": 0.67062, "Y1": 0.1162, "X2": 0.70356, "Y2": 0.116, "X3": 0.70356, "Y3": 0.1318, "X4": 0.67194, "Y4": 0.1328, "page": 0, "Index": 3}, {"Word": "Thorax", "Confidence": 0.485, "X1": 0.67194, "Y1": 0.1412, "X2": 0.71673, "Y2": 0.141, "X3": 0.71542, "Y3": 0.1558, "X4": 0.67194, "Y4": 0.1568, "page": 0, "Index": 4}, {"Word": "1986:41:203-207", "Confidence": 0.63, "X1": 0.72069, "Y1": 0.1402, "X2": 0.82872, "Y2": 0.14, "X3": 0.82872, "Y3": 0.1558, "X4": 0.71937, "Y4": 0.1558, "page": 0, "Index": 5}, {"Word": "and", "Confidence": 0.998, "X1": 0.7365, "Y1": 0.1962, "X2": 0.78524, "Y2": 0.196, "X3": 0.78524, "Y3": 0.2178, "X4": 0.7365, "Y4": 0.2188, "page": 0, "Index": 6}, {"Word": "Validity", "Confidence": 0.995, "X1": 0.14229, "Y1": 0.1952, "X2": 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The exact tar yields", "Confidence": 0.6835, "X1": 0.50461, "Y1": 0.3082, "X2": 0.85639, "Y2": 0.308, "X3": 0.85639, "Y3": 0.3208, "X4": 0.50461, "Y4": 0.3208, "page": 0}, {"Word": "smoker of plain manufactured cigarette smokers", "Confidence": 0.69333, "X1": 0.15415, "Y1": 0.3212, "X2": 0.49407, "Y2": 0.321, "X3": 0.49407, "Y3": 0.3338, "X4": 0.15415, "Y4": 0.3328, "page": 0}, {"Word": "have usually been deduced from the brand name of", "Confidence": 0.85622, "X1": 0.50725, "Y1": 0.3202, "X2": 0.85507, "Y2": 0.32, "X3": 0.85507, "Y3": 0.3338, "X4": 0.50725, "Y4": 0.3338, "page": 0}, {"Word": "formed a substantial proportion of all male smokers", "Confidence": 0.86188, "X1": 0.15283, "Y1": 0.3332, "X2": 0.49275, "Y2": 0.333, "X3": 0.49275, "Y3": 0.3458, "X4": 0.15283, "Y4": 0.3458, "page": 0}, {"Word": "the cigarette currently smoked as given on a self", "Confidence": 0.71222, "X1": 0.50461, "Y1": 0.3322, "X2": 0.85903, "Y2": 0.332, "X3": 0.85903, "Y3": 0.3468, "X4": 0.50461, "Y4": 0.3458, "page": 0}, {"Word": "of manufactured cigarettes, and our Andings cannot", "Confidence": 0.80514, "X1": 0.15547, "Y1": 0.3462, "X2": 0.49407, "Y2": 0.346, "X3": 0.49407, "Y3": 0.3598, "X4": 0.15547, "Y4": 0.3588, "page": 0}, {"Word": "administered or interviewer administered question.", "Confidence": 0.8052, "X1": 0.50988, "Y1": 0.3452, "X2": 0.85507, "Y2": 0.345, "X3": 0.85507, "Y3": 0.3588, "X4": 0.50988, "Y4": 0.3588, "page": 0}, {"Word": "confirm the accuracy of studies that collected infor-", "Confidence": 0.88513, "X1": 0.15415, "Y1": 0.3582, "X2": 0.49144, "Y2": 0.358, "X3": 0.49144, "Y3": 0.3718, "X4": 0.15415, "Y4": 0.3718, "page": 0}, {"Word": "asire.3 19 13 1\u00aa Very few of the studies make any refer.", "Confidence": 0.705, "X1": 0.50593, "Y1": 0.3592, "X2": 0.85375, "Y2": 0.359, "X3": 0.85375, "Y3": 0.3728, "X4": 0.50593, "Y4": 0.3698, "page": 0}, {"Word": "madon about type of cigarette smoked at that time by", "Confidence": 0.8469, "X1": 0.15547, "Y1": 0.3712, "X2": 0.49539, "Y2": 0.371, "X3": 0.49539, "Y3": 0.3838, "X4": 0.15547, "Y4": 0.3838, "page": 0}, {"Word": "enos to the amount of information that needs to be", "Confidence": 0.6541, "X1": 0.50988, "Y1": 0.3712, "X2": 0.85507, "Y2": 0.371, "X3": 0.85507, "Y3": 0.3838, "X4": 0.50988, "Y4": 0.3828, "page": 0}, {"Word": "means of self or interviewer administered question-", "Confidence": 0.87971, "X1": 0.15415, "Y1": 0.3832, "X2": 0.49539, "Y2": 0.383, "X3": 0.49539, "Y3": 0.3958, "X4": 0.15415, "Y4": 0.3958, "page": 0}, {"Word": "collected to identify the precise brand of cigarette", "Confidence": 0.82888, "X1": 0.51383, "Y1": 0.3832, "X2": 0.85639, "Y2": 0.383, "X3": 0.85639, "Y3": 0.3958, "X4": 0.51383, "Y4": 0.3948, "page": 0}, {"Word": "smoked out of all those on the market. Schenker er af\"", "Confidence": 0.75255, "X1": 0.51383, "Y1": 0.3952, "X2": 0.85375, "Y2": 0.395, "X3": 0.85375, "Y3": 0.4078, "X4": 0.51383, "Y4": 0.4078, "page": 0}, {"Word": "paires, rather than from the cigarette packet itself.", "Confidence": 0.78625, "X1": 0.15415, "Y1": 0.3962, "X2": 0.47826, "Y2": 0.396, "X3": 0.47826, "Y3": 0.4088, "X4": 0.15415, "Y4": 0.4088, "page": 0}, {"Word": "Nous of the prospective, cross sectional, or case-", "Confidence": 0.74938, "X1": 0.16996, "Y1": 0.4082, "X2": 0.49802, "Y2": 0.408, "X3": 0.49802, "Y3": 0.4228, "X4": 0.16996, "Y4": 0.4218, "page": 0}, {"Word": "included specifications of lengths, Alter, packet type", "Confidence": 0.588, "X1": 0.51383, "Y1": 0.4082, "X2": 0.85244, "Y2": 0.408, "X3": 0.85244, "Y3": 0.4218, "X4": 0.51383, "Y4": 0.4208, "page": 0}, {"Word": "control studies that have compared the morbidity and", "Confidence": 0.75075, "X1": 0.15415, "Y1": 0.4212, "X2": 0.49407, "Y2": 0.421, "X3": 0.49407, "Y3": 0.4348, "X4": 0.15415, "Y4": 0.4338, "page": 0}, {"Word": "(soft packet or box), and favour (regular or menthol)", "Confidence": 0.72556, "X1": 0.5112, "Y1": 0.4202, "X2": 0.85639, "Y2": 0.42, "X3": 0.85639, "Y3": 0.4338, "X4": 0.5112, "Y4": 0.4328, "page": 0}, {"Word": "mortality of smokers of cigarettes of different tar", "Confidence": 0.79512, "X1": 0.15283, "Y1": 0.4332, "X2": 0.49671, "Y2": 0.433, "X3": 0.49671, "Y3": 0.4468, "X4": 0.15283, "Y4": 0.4468, "page": 0}, {"Word": "under cigarette brand, and our results confirm that", "Confidence": 0.78012, "X1": 0.5112, "Y1": 0.4332, "X2": 0.85507, "Y2": 0.433, "X3": 0.85507, "Y3": 0.4458, "X4": 0.5112, "Y4": 0.4458, "page": 0}, {"Word": "this sort of detall is necessary. We recommend, how.", "Confidence": 0.80189, "X1": 0.51383, "Y1": 0.4452, "X2": 0.85507, "Y2": 0.445, "X3": 0.85507, "Y3": 0.4578, "X4": 0.51383, "Y4": 0.4578, "page": 0}, {"Word": "yields have so far used the tar group, indicated on the", "Confidence": 0.805, "X1": 0.15547, "Y1": 0.4452, "X2": 0.49407, "Y2": 0.445, "X3": 0.49407, "Y3": 0.4588, "X4": 0.15547, "Y4": 0.4588, "page": 0}, {"Word": "cigarette packet, as a basis on which to allocate", "Confidence": 0.76844, "X1": 0.15679, "Y1": 0.4582, "X2": 0.49407, "Y2": 0.458, "X3": 0.49407, "Y3": 0.4718, "X4": 0.15679, "Y4": 0.4718, "page": 0}, {"Word": "ever, that smokers should be asked to return an empty", "Confidence": 0.8134, "X1": 0.51515, "Y1": 0.4582, "X2": 0.85507, "Y2": 0.458, "X3": 0.85507, "Y3": 0.4708, "X4": 0.51515, "Y4": 0.4708, "page": 0}, {"Word": "smokers to higher or lower tar smoking groups for", "Confidence": 0.78622, "X1": 0.15547, "Y1": 0.4712, "X2": 0.49275, "Y2": 0.471, "X3": 0.49275, "Y3": 0.4858, "X4": 0.15547, "Y4": 0.4848, "page": 0}, {"Word": "packet of the cigarette usually smoked with a self", "Confidence": 0.88967, "X1": 0.50988, "Y1": 0.4702, "X2": 0.85903, "Y2": 0.47, "X3": 0.85903, "Y3": 0.4838, "X4": 0.50988, "Y4": 0.4848, "page": 0}, {"Word": "administered questionnaire, and we found from &", "Confidence": 0.74286, "X1": 0.5112, "Y1": 0.4842, "X2": 0.85771, "Y2": 0.484, "X3": 0.85771, "Y3": 0.4978, "X4": 0.5112, "Y4": 0.4968, "page": 0}, {"Word": "analysis. If this were the case and such information", "Confidence": 0.659, "X1": 0.15283, "Y1": 0.4842, "X2": 0.49275, "Y2": 0.484, "X3": 0.49275, "Y3": 0.4988, "X4": 0.15283, "Y4": 0.4968, "page": 0}, {"Word": "were collected by self administered questionnaire,", "Confidence": 0.82033, "X1": 0.15547, "Y1": 0.4972, "X2": 0.49275, "Y2": 0.497, "X3": 0.49275, "Y3": 0.5108, "X4": 0.15547, "Y4": 0.5098, "page": 0}, {"Word": "postal survey of 20 000 households that 90% of", "Confidence": 0.89111, "X1": 0.50988, "Y1": 0.4952, "X2": 0.85639, "Y2": 0.495, "X3": 0.85639, "Y3": 0.5098, "X4": 0.50988, "Y4": 0.5108, "page": 0}, {"Word": "this study suggests that, whereas nearly all of the", "Confidence": 0.67456, "X1": 0.15283, "Y1": 0.5082, "X2": 0.49275, "Y2": 0.508, "X3": 0.49275, "Y3": 0.5228, "X4": 0.15283, "Y4": 0.5218, "page": 0}, {"Word": "mokers were willing to do this, 1\u00aa", "Confidence": 0.63614, "X1": 0.51515, "Y1": 0.5072, "X2": 0.73386, "Y2": 0.507, "X3": 0.73386, "Y3": 0.5198, "X4": 0.51515, "Y4": 0.5218, "page": 0}, {"Word": "smokers allocated to a \"low\" tar group would", "Confidence": 0.761, "X1": 0.15679, "Y1": 0.5222, "X2": 0.49671, "Y2": 0.522, "X3": 0.49671, "Y3": 0.5348, "X4": 0.15679, "Y4": 0.5348, "page": 0}, {"Word": "Most cross sectional and some case-control studies", "Confidence": 0.77086, "X1": 0.52701, "Y1": 0.5212, "X2": 0.85771, "Y2": 0.521, "X3": 0.85771, "Y3": 0.5348, "X4": 0.52701, "Y4": 0.5338, "page": 0}, {"Word": "actually smoke \"tow\" tar cigarettes, as many as 15", "Confidence": 0.78822, "X1": 0.1581, "Y1": 0.5342, "X2": 0.49407, "Y2": 0.534, "X3": 0.49407, "Y3": 0.5478, "X4": 0.1581, "Y4": 0.5478, "page": 0}, {"Word": "have compared smokers of cigarettes of different tas", "Confidence": 0.78375, "X1": 0.51252, "Y1": 0.5342, "X2": 0.85771, "Y2": 0.534, "X3": 0.85771, "Y3": 0.5478, "X4": 0.51252, "Y4": 0.5478, "page": 0}, {"Word": "out of the 75 (20%) smokers allocated to the", "Confidence": 0.858, "X1": 0.15679, "Y1": 0.5462, "X2": 0.49407, "Y2": 0.546, "X3": 0.49407, "Y3": 0.5598, "X4": 0.15679, "Y4": 0.5598, "page": 0}, {"Word": "yields according to their current smoking habits only.", "Confidence": 0.83575, "X1": 0.51515, "Y1": 0.5482, "X2": 0.85903, "Y2": 0.548, "X3": 0.85903, "Y3": 0.5608, "X4": 0.51515, "Y4": 0.5598, "page": 0}, {"Word": "\"middle\" tar cigarette group would have bem more", "Confidence": 0.74913, "X1": 0.15679, "Y1": 0.5592, "X2": 0.49671, "Y2": 0.559, "X3": 0.49671, "Y3": 0.5718, "X4": 0.15679, "Y4": 0.5718, "page": 0}, {"Word": "A recrut trend is for studies to inquire about past as", "Confidence": 0.80118, "X1": 0.51515, "Y1": 0.5592, "X2": 0.85771, "Y2": 0.559, "X3": 0.85771, "Y3": 0.5718, "X4": 0.51515, "Y4": 0.5718, "page": 0}, {"Word": "correctly assigned to the \"low\" or \"low middle\" tar", "Confidence": 0.81333, "X1": 0.15679, "Y1": 0.5712, "X2": 0.49539, "Y2": 0.571, "X3": 0.49539, "Y3": 0.5838, "X4": 0.15679, "Y4": 0.5848, "page": 0}, {"Word": "well as present cigarette brands smoked. In the", "Confidence": 0.71025, "X1": 0.51647, "Y1": 0.5712, "X2": 0.85903, "Y2": 0.571, "X3": 0.85903, "Y3": 0.5848, "X4": 0.51647, "Y4": 0.5848, "page": 0}, {"Word": "group (table 2). This erroneous allocation of \"low\"", "Confidence": 0.77487, "X1": 0.15679, "Y1": 0.5842, "X2": 0.49539, "Y2": 0.584, "X3": 0.49539, "Y3": 0.5978, "X4": 0.15679, "Y4": 0.5988, "page": 0}, {"Word": "case-control study carried out by Lubin et af\"\"", "Confidence": 0.59775, "X1": 0.5112, "Y1": 0.5822, "X2": 0.86034, "Y2": 0.582, "X3": 0.86034, "Y3": 0.5958, "X4": 0.5112, "Y4": 0.5978, "page": 0}, {"Word": "tar mokers to a higher group would be expected", "Confidence": 0.78267, "X1": 0.1581, "Y1": 0.5972, "X2": 0.49671, "Y2": 0.597, "X3": 0.49671, "Y3": 0.6108, "X4": 0.1581, "Y4": 0.6108, "page": 0}, {"Word": "respondents were expected to recall up to the last four", "Confidence": 0.928, "X1": 0.5191, "Y1": 0.5972, "X2": 0.85903, "Y2": 0.597, "X3": 0.85903, "Y3": 0.6098, "X4": 0.5191, "Y4": 0.6098, "page": 0}, {"Word": "to increase the chances of missing & significant", "Confidence": 0.63625, "X1": 0.16074, "Y1": 0.6092, "X2": 0.49671, "Y2": 0.609, "X3": 0.49671, "Y3": 0.6238, "X4": 0.16074, "Y4": 0.6228, "page": 0}, {"Word": "cigarette brands smoked but the authors were not", "Confidence": 0.74862, "X1": 0.52042, "Y1": 0.6102, "X2": 0.85903, "Y2": 0.61, "X3": 0.85903, "Y3": 0.6228, "X4": 0.52042, "Y4": 0.6228, "page": 0}, {"Word": "difference in morbidity or mortality between the", "Confidence": 0.83, "X1": 0.1581, "Y1": 0.6232, "X2": 0.49671, "Y2": 0.623, "X3": 0.49671, "Y3": 0.6358, "X4": 0.1581, "Y4": 0.6358, "page": 0}, {"Word": "able to test the validity of the recall. In our study only", "Confidence": 0.86342, "X1": 0.51647, "Y1": 0.6222, "X2": 0.86166, "Y2": 0.622, "X3": 0.86166, "Y3": 0.6368, "X4": 0.51647, "Y4": 0.6358, "page": 0}, {"Word": "groups.", "Confidence": 0.495, "X1": 0.15679, "Y1": 0.6362, "X2": 0.21344, "Y2": 0.636, "X3": 0.21344, "Y3": 0.6488, "X4": 0.15679, "Y4": 0.6488, "page": 0}, {"Word": "about 49% of the brands that smokers claimed they", "Confidence": 0.96267, "X1": 0.51252, "Y1": 0.6362, "X2": 0.85903, "Y2": 0.636, "X3": 0.85903, "Y3": 0.6498, "X4": 0.51252, "Y4": 0.6478, "page": 0}, {"Word": "Nevertheless the size of the quantitative error indi-", "Confidence": 0.7805, "X1": 0.15942, "Y1": 0.6472, "X2": 0.50066, "Y2": 0.647, "X3": 0.50066, "Y3": 0.6628, "X4": 0.15942, "Y4": 0.6618, "page": 0}, {"Word": "smoked 12 years ago were confirmed by records made", "Confidence": 0.88322, "X1": 0.5112, "Y1": 0.6492, "X2": 0.86034, "Y2": 0.649, "X3": 0.86034, "Y3": 0.6618, "X4": 0.5112, "Y4": 0.6618, "page": 0}, {"Word": "cated by table 2 might still allow a comparison", "Confidence": 0.80444, "X1": 0.1581, "Y1": 0.6612, "X2": 0.49934, "Y2": 0.661, "X3": 0.49934, "Y3": 0.6758, "X4": 0.1581, "Y4": 0.6768, "page": 0}, {"Word": "at that time. The Heart Disease Prevention Project's", "Confidence": 0.84275, "X1": 0.51647, "Y1": 0.6612, "X2": 0.86034, "Y2": 0.661, "X3": 0.86034, "Y3": 0.6748, "X4": 0.51647, "Y4": 0.6748, "page": 0}, {"Word": "between people who report smoking different brands", "Confidence": 0.91457, "X1": 0.1581, "Y1": 0.6752, "X2": 0.49802, "Y2": 0.675, "X3": 0.49802, "Y3": 0.6888, "X4": 0.1581, "Y4": 0.6888, "page": 0}, {"Word": "questionnaire used to obtain data on the brand of", "Confidence": 0.873, "X1": 0.5191, "Y1": 0.6742, "X2": 0.86166, "Y2": 0.674, "X3": 0.86166, "Y3": 0.6888, "X4": 0.5191, "Y4": 0.6878, "page": 0}, {"Word": "to be useful. Given that 19, 13. and 8 mg are the Ever-", "Confidence": 0.77592, "X1": 0.15679, "Y1": 0.6872, "X2": 0.50066, "Y2": 0.687, "X3": 0.50066, "Y3": 0.7018, "X4": 0.15679, "Y4": 0.7008, "page": 0}, {"Word": "cigarette smoked in 1971-J asked about the brand of", "Confidence": 0.87322, "X1": 0.5191, "Y1": 0.6872, "X2": 0.86166, "Y2": 0.687, "X3": 0.86166, "Y3": 0.7008, "X4": 0.5191, "Y4": 0.6998, "page": 0}, {"Word": "age tar levels of the three tar groups \"middle.\" \"law", "Confidence": 0.8327, "X1": 0.16074, "Y1": 0.7002, "X2": 0.49802, "Y2": 0.7, "X3": 0.49802, "Y3": 0.7138, "X4": 0.16074, "Y4": 0.7138, "page": 0}, {"Word": "cigarette or hand rolling tobacco usually smoked.", "Confidence": 0.797, "X1": 0.51779, "Y1": 0.6992, "X2": 0.85903, "Y2": 0.699, "X3": 0.85903, "Y3": 0.7128, "X4": 0.51779, "Y4": 0.7128, "page": 0}, {"Word": "middle,\" \"low\" on the cigarette packet, then for the", "Confidence": 0.85211, "X1": 0.16206, "Y1": 0.7132, "X2": 0.49934, "Y2": 0.713, "X3": 0.49934, "Y3": 0.7268, "X4": 0.16206, "Y4": 0.7258, "page": 0}, {"Word": "Thus subjects were allowed to give only one answer", "Confidence": 0.83044, "X1": 0.5191, "Y1": 0.7122, "X2": 0.86298, "Y2": 0.712, "X3": 0.86298, "Y3": 0.7258, "X4": 0.5191, "Y4": 0.7258, "page": 0}, {"Word": "150 people who supplied valid data on the smoking of", "Confidence": 0.8772, "X1": 0.16337, "Y1": 0.7262, "X2": 0.49934, "Y2": 0.726, "X3": 0.49934, "Y3": 0.7388, "X4": 0.16337, "Y4": 0.7378, "page": 0}, {"Word": "regarding the brand smoked. An appreciable propor-", "Confidence": 0.80886, "X1": 0.52042, "Y1": 0.7262, "X2": 0.86034, "Y2": 0.726, "X3": 0.86034, "Y3": 0.7388, "X4": 0.52042, "Y4": 0.7388, "page": 0}, {"Word": "manufactured cigarettes on both, the means for the", "Confidence": 0.81288, "X1": 0.16206, "Y1": 0.7382, "X2": 0.50329, "Y2": 0.738, "X3": 0.50329, "Y3": 0.7518, "X4": 0.16206, "Y4": 0.7518, "page": 0}, {"Word": "tion of male cigarette smokers used boch manu-", "Confidence": 0.69112, "X1": 0.51779, "Y1": 0.7372, "X2": 0.86693, "Y2": 0.737, "X3": 0.86693, "Y3": 0.7528, "X4": 0.51779, "Y4": 0.7518, "page": 0}, {"Word": "questionnaire groups would be: middle high -", "Confidence": 0.68957, "X1": 0.16337, "Y1": 0.7502, "X2": 0.49934, "Y2": 0.75, "X3": 0.49934, "Y3": 0.7628, "X4": 0.16337, "Y4": 0.7638, "page": 0}, {"Word": "factured and band rolled cigarettes. Possibly part of", "Confidence": 0.75362, "X1": 0.5191, "Y1": 0.7492, "X2": 0.86166, "Y2": 0.749, "X3": 0.86166, "Y3": 0.7638, "X4": 0.5191, "Y4": 0.7638, "page": 0}, {"Word": "17.2mg ((7 x 19 + 3 = 13)/10); middle - 17.4 mg.", "Confidence": 0.67758, "X1": 0.16337, "Y1": 0.7622, "X2": 0.49934, "Y2": 0.762, "X3": 0.49934, "Y3": 0.7758, "X4": 0.16337, "Y4": 0.7758, "page": 0}, {"Word": "the 51% discrepancy found between the brand", "Confidence": 0.81014, "X1": 0.52042, "Y1": 0.7622, "X2": 0.85903, "Y2": 0.762, "X3": 0.85903, "Y3": 0.7758, "X4": 0.52042, "Y4": 0.7748, "page": 0}, {"Word": "low middle = 13.7mg; low - 8.5mg. Thus, apart", "Confidence": 0.52044, "X1": 0.15942, "Y1": 0.7752, "X2": 0.50198, "Y2": 0.775, "X3": 0.50198, "Y3": 0.7878, "X4": 0.1581, "Y4": 0.7868, "page": 0}, {"Word": "thought to be smoked at the start of the project and", "Confidence": 0.90136, "X1": 0.5191, "Y1": 0.7752, "X2": 0.85903, "Y2": 0.775, "X3": 0.85903, "Y3": 0.7868, "X4": 0.5191, "Y4": 0.7868, "page": 0}, {"Word": "from the middle bish group, there still seems to be a", "Confidence": 0.84645, "X1": 0.16206, "Y1": 0.7872, "X2": 0.49934, "Y2": 0.787, "X3": 0.49934, "Y3": 0.7998, "X4": 0.16206, "Y4": 0.7998, "page": 0}, {"Word": "the brand recorded at the time arose because the men", "Confidence": 0.8787, "X1": 0.52042, "Y1": 0.7872, "X2": 0.85903, "Y2": 0.787, "X3": 0.85903, "Y3": 0.7998, "X4": 0.52042, "Y4": 0.7998, "page": 0}, {"Word": "substantial difference in tar yields between people", "Confidence": 0.71814, "X1": 0.1581, "Y1": 0.7992, "X2": 0.49934, "Y2": 0.799, "X3": 0.49934, "Y3": 0.8148, "X4": 0.1581, "Y4": 0.8138, "page": 0}, {"Word": "were allowed to give only one answer on the HDPP", "Confidence": 0.916, "X1": 0.5191, "Y1": 0.7992, "X2": 0.86034, "Y2": 0.799, "X3": 0.86034, "Y3": 0.8118, "X4": 0.5191, "Y4": 0.8128, "page": 0}, {"Word": "who report smoking different brands.", "Confidence": 0.8434, "X1": 0.16206, "Y1": 0.8112, "X2": 0.40711, "Y2": 0.811, "X3": 0.40711, "Y3": 0.8238, "X4": 0.16206, "Y4": 0.8248, "page": 0}, {"Word": "questionnaire. 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