Update README.md

README.md

@@ -1,11 +1,14 @@
 # Human variants
-A curated set of variants from three sources: ClinVar, OMIM and gnomAD.
+A curated set of variants from three sources: ClinVar, COSMIC, OMIM and gnomAD.
 
 ## Data sources
 
 **ClinVar**:
 Missense variants considered "Pathogenic" by human labelers.
 
+**COSMIC**:
+Somatic missense variants with a frequency at least 0.1% in cancer samples (whole-genome and whole-exome sequencing only).
+
 **OMIM**:
 Regulatory variants considered "Pathogenic" by human labelers, curated in [this paper](https://doi.org/10.1016/j.ajhg.2016.07.005).
 
@@ -24,6 +27,11 @@ Subset - ClinVar Pathogenic vs. gnomAD common (missense) (can specify `num_proc`
 dataset = dataset.filter(lambda v: v["source"]=="ClinVar" or (v["label"]=="Common" and "missense" in v["consequence"]))
 ```
 
+Subset - COSMIC frequent vs. gnomAD common (missense):
+```python
+dataset = dataset.filter(lambda v: v["source"]=="COSMIC" or (v["label"]=="Common" and "missense" in v["consequence"]))
+```
+
 Subset - OMIM Pathogenic vs. gnomAD common (regulatory):
 ```python
 cs = ["5_prime_UTR", "upstream_gene", "intergenic", "3_prime_UTR", "non_coding_transcript_exon"]