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  license: apache-2.0
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  license: apache-2.0
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+ Mirror of OpenFold parameters as provided in https://github.com/aqlaboratory/openfold. Stopgap solution as the original download link was down. All rights to the authors.
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+
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+ OpenFold model parameters, v. 06_22.
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+
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+ # Training details:
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+
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+ Trained using OpenFold on 44 A100s using the training schedule from Table 4 in
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+ the AlphaFold supplement. AlphaFold was used as the pre-distillation model.
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+ Training data is hosted publicly in the "OpenFold Training Data" RODA repository.
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+
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+ # Parameter files:
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+
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+ Parameter files fall into the following categories:
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+
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+ initial_training.pt:
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+ OpenFold at the end of the initial training phase.
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+ finetuning_x.pt:
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+ Checkpoints in chronological order corresponding to peaks in the
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+ validation LDDT-Ca during the finetuning phase. Roughly evenly spaced
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+ across the 45 finetuning epochs.
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+ finetuning_ptm_x.pt:
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+ Checkpoints in chronological order corresponding to peaks inthe pTM
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+ training phase, a short additional training phase that takes place
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+ after finetuning. Models in this category include the pTM module and
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+ comprise the most recent of the checkpoints in this directory.
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+
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+ Average validation LDDT-Ca scores for each of the checkpoints are listed below.
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+ The validation set contains approximately 180 chains drawn from CAMEO over a
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+ three-month period at the end of 2021.
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+
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+ initial_training: 0.9088
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+ finetuning_ptm_1: 0.9075
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+ finetuning_ptm_2: 0.9097
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+ finetuning_1: 0.9089
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+ finetuning_2: 0.9061
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+ finetuning_3: 0.9075
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+ finetuning_4: 0.9059
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+ finetuning_5: 0.9054